LOCUS       DAMJVG010000001       137625 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.001, whole genome shotgun sequence.
ACCESSION   DAMJVG010000001 DAMJVG010000000
VERSION     DAMJVG010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 137625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 137625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..137625
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.001"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            109..300
                     /locus_tag="PC512_000001"
     CDS             109..300
                     /locus_tag="PC512_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HDF2439781.1"
                     /translation="MKKVALILAIIGALNWGAIGILGTDLIGSIFGGTYEMVSRIIYF
                     IVGLAGLYLIPSLMSDDRE"
     gene            455..1864
                     /locus_tag="PC512_000002"
     CDS             455..1864
                     /locus_tag="PC512_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDF2439782.1"
                     /translation="MFIINELNKIVNEEVISFHMPGHKKGQVYKKLGYKDILKNLYKM
                     DTTEILGTDNLHFPEGIIKNSQKKASRVFKSDYTCYLVNGSSCGIQSAIMSVCSPKSK
                     IITNRDCHQSVINGCILGDIDIEYVPCEISEETNILKGISISNVIDIIDKNLDAKAVL
                     LTYPTYYGMTYDLEYICNYAHSKKMVVIVDEAHGAHLGLSERLPKTALEQGADIVVQS
                     THKTLPAFTQSSMIHIQGDRVDIDKILNMLRITESSSPSYLLLSSLELAVDIYENKGK
                     ELMEELLNNIITFKNKVDSNINIYDTNDKTKIFISSKNMGLTGYELENILRNKYNIQV
                     ELSNYYGVLLICTIGNTAEDFSSLETALNNVVKEDFKFEKLENKKYPVVIPKKILTPR
                     EAFYKTKKSVKIYDSIGKVCGECIVPYPPGISVISPGEVISKEIIDYLMFCHSKGMIV
                     SGLKDVDLNFIQVIDLEDI"
     gene            1995..2684
                     /locus_tag="PC512_000003"
     CDS             1995..2684
                     /locus_tag="PC512_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate kinase"
                     /protein_id="HDF2439783.1"
                     /translation="MKGKLIIIESGSDASGKATQTEILYERLKKEGYMIKKVEYPNYE
                     SPSSALVKMYLKGDFGKNASDVDPYIASTFFTADRYASFKTDWEEFYNEGGIIIADRY
                     TTSNMVHQASKMDICDREEYLNWLADYEFNLFKIPQPDCVIFLDVPIEFSKKLMENRK
                     NKITGEEKKDIHESDIEYLEKSYNNALYIADKYDWKKINCVLDNKLRSIESIHNEIYK
                     IVLDSIKPMER"
     gene            2687..3622
                     /locus_tag="PC512_000004"
     CDS             2687..3622
                     /locus_tag="PC512_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HDF2439784.1"
                     /translation="MYFENIIGQDFAKKYLTNSIKKNKLNNAYMFEGMDGIGKKKFAD
                     ELSKLLLDYENLENSPDYVLIKPDGNSIKIAQIRNLQSDIVIRPHKDYKIYIINNAEK
                     MTVEAQNALLKTLEEPPNYAIIILVTNNKESLLETIKSRCDIIKFSPIPIEDLKRYLI
                     NTGIEEERAQLLAIFSRGSIENALNLSQSSEFSMMREDIQQYIQIMLDKNIVEILNIP
                     NNMEKYRGKIIALLDMMINYFRDIILLKENVNKNMLINVDKLVFIQNMNGKISYSQLS
                     KIIDIIEDAKSKIKSNCNFNISIQVMSLNIYEVIK"
     gene            3619..4512
                     /locus_tag="PC512_000005"
     CDS             3619..4512
                     /locus_tag="PC512_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HDF2439785.1"
                     /translation="MIKIVGIRFKSAGKIYYFDPVDFNIEQDMDVVVETARGLEYGKV
                     VVGPKDMDESELVSPLKPIIRIATEEDKKVYLENKEKAKETFELCQQKIKEHELTMFL
                     IDCEYTFDRNKLIFYFTAEGRIDFRELVKDLAAIFKTRIELRQIGVRDEAKSIGGLGP
                     CGRKLCCSSWLGDFQPVSIKMAKDQSLSLNPTKISGICGRLFCCLKYEHDVYSEAIEK
                     MPVVGALVQSDDGKGKVVEVNPLLEQIKVEFQDKTVKIYTREDIKILREPKKCDGCGG
                     KCKDNDGLDEATLRELKKLED"
     gene            4590..5336
                     /locus_tag="PC512_000006"
     CDS             4590..5336
                     /locus_tag="PC512_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HDF2439786.1"
                     /translation="MQLKDSERIDDLQLKGLKIIQDTNGFCFGIDAVLLANFTKIKKD
                     AKVVDLGTGTGIIPILIAGKSEAKKIIGVEIQEDVYEMATRSIKLNGLEERVEIINED
                     IKYIDKVLDINGYHVVTSNPPYMHIDGIKNPNDKKAISRHEVRCNLEDVIRAASRLVM
                     PRGKFFMIHRPTRLVDIITLGRKYKLEPKVIQFVHPRPQKAPNLVLVQFVKDGRPELK
                     ILDPLYVYGEDGNYTKELKAIYNNKDIGEL"
     gene            5337..6170
                     /gene="rsmI"
                     /locus_tag="PC512_000007"
     CDS             5337..6170
                     /gene="rsmI"
                     /locus_tag="PC512_000007"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HDF2439787.1"
                     /translation="MSGKLYICPTPIGNLEDITYRTLRILKEVDLIAAEDTRHSIKLL
                     NHFEISKPLTSYHEHNKDSKGDYLINKLIDGENIALISDAGMPGISDPGEEIIKQAIQ
                     NNIEIEVLPGATAFVTALVGSGMDTHRFIFEGFLDRDKKVRKAQLEELKEESRTIIFY
                     ESPHRLKDTLKDMLKILGNRNISINRELTKKYQEIIRENIETTIKIFEEKEVRGEFVL
                     IVEGFHGEKSKKENYDGLTDREYVLKLIESGMNKKDAIKIVCKDRKLKKDVVYKQVLD
                     L"
     gene            6193..6897
                     /locus_tag="PC512_000008"
     CDS             6193..6897
                     /locus_tag="PC512_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HDF2439788.1"
                     /translation="MEIGKIIIESLKREDTHKIFIELDNKHELEKIIPKISCMKSVGE
                     CKYHVVNCFEHSINALKELEIVLNDKDFFPIHLRKHVSNYLKTYIEEGINKLHVLKLG
                     TFLHDIGKPDSMTLDETGRVHFTNHEKIGAQIIDNMGIKLELSTETYRLISKYVRYHM
                     ILLSLYKKNDLSRKELINVFNLVDEDTIGVIMLGYADIVSTVKLLGKSGEVSVLKTYM
                     EYILTNYLYKSNYTHV"
     gene            complement(7085..7513)
                     /locus_tag="PC512_000009"
     CDS             complement(7085..7513)
                     /locus_tag="PC512_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007287587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HDF2439789.1"
                     /translation="MDVTDYRIIEILQDDGRISMKDLGKIVGLTSPAVSERVKRLEES
                     GVIEGYKAIVNPDSLGRVIKAFIHISLPSNGYTEFIESAAKDPRIVECHHITGDDCLL
                     LKVIVKDMYELENVIDTIKKIGSTKTSVILSTPIQAKSIL"
     gene            complement(7550..8980)
                     /locus_tag="PC512_000010"
     CDS             complement(7550..8980)
                     /locus_tag="PC512_000010"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HDF2439790.1"
                     /translation="MRNLTLLTDLYQLTMLNGYFEKNIHEDIVVFDMFFRKNACDGGY
                     TIVCGIDQVVEYIDNLHFSDEDLEYLKNLNLFSDKFLKFLKEFKFTGDIYAVEEGTIM
                     FPNEPLITVKAPLYQAQLIETALLTIVNFQSLIATKASRVCFAAQGDPVFEFGLRRAQ
                     GPDAGIYGARAAVVGGCAGTANVLAGKMFDIPIIGTQAHSWVQKFDNELEAFQAYADV
                     YPDKCLLLVDTYDVLNSGVPNAIKVFKNISEKGYKPMGIRLDSGDLAYLSKEAKKQLD
                     NAGFSDISITASNDLDEYTITSLKAEGATINSWGVGTKLITSFDSPSLGGVYKLAASC
                     EKGVLEPKIKISENPEKINNPGYKKVIRIYNEDNKAEADLIMLHDEVIDESKPLEIFH
                     PTYTWKTKVFTNYKVKELLKPLYIKGRCKYNKKAVLEIKNHVQYELSTIWEQYKRLSK
                     PHIYKVDLSRNLWYLKTQMIDSKKVL"
     gene            9112..9696
                     /locus_tag="PC512_000011"
     CDS             9112..9696
                     /locus_tag="PC512_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore maturation protein A"
                     /protein_id="HDF2439791.1"
                     /translation="MIIIGKIWFYMVSIGIIGSLISKNMGELNKVILSETSKGIEFAI
                     SLAGIMALWMGIMNIAKESGLIEKIGQKLNPIMRRLFPSIPKGHKAMSYIVMNIALNM
                     LGAGNGATAFGLKAMSELQTLNNKKDTATNDMIMFMVINISSIQIIPFTIIKLRMDMG
                     AQNPSEIIFTTLFATIISTAVAIITCKFFQRRYR"
     gene            9712..10233
                     /locus_tag="PC512_000012"
     CDS             9712..10233
                     /locus_tag="PC512_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore maturation protein"
                     /protein_id="HDF2439792.1"
                     /translation="MEIFSNLLIPIIILYIVVYGKYKKIDVYDSFVKGAIDGLKAAWD
                     ILPYIIGIFLAIGIFKTGKGLDMLEWLFTPIANMMSIPKELIGLISVKPLSGSGALGM
                     YSELANRVGIGSLVEKMGATIVGSSETIFYTMAIYYGSLKIKNTRHTLSCAMISHVAG
                     VIAAVFICYVIFV"
     misc_binding    10299..10545
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            10629..12566
                     /gene="metG"
                     /locus_tag="PC512_000013"
     CDS             10629..12566
                     /gene="metG"
                     /locus_tag="PC512_000013"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HDF2439793.1"
                     /translation="MSKPSFYVTTPIYYPSGGLHIGHTYSTVAADTIARFKRFCGYDV
                     KFLTGTDEHGEKIQKKAIEQGMSEIEYLDGMIKDIKALWNTMDISYDDFIRTTEKRHT
                     DIIQKIFTKLYEQGDIYKGEYEGRYCTPCESFWTESQLLEGNKCPDCGRETYLVKEES
                     YFFRLSKYEDRLKELFKDDSFCFPAARKNEMVANFLDKGLEDLSVTRTTFDWGIKVPF
                     DEKHVIYVWVDALCNYITALGYMTDNDEEFKKYWPANVQIVGKEIVRFHTIIWPALLM
                     ALGLEVPKQVFGHGWILFADDKMSKSKGNVVYPEPIIERYGIDTLKYFLLREFAFGQD
                     GSYTHRNFVTRINYDLANDLGNLISRTVAMVEKYNNGIIPTAKVSTNFDADLKEQAVS
                     TRENFEAEMDKMQFHEALESVWKLVRRTNKYIDETMPWALAKDETKKDELDTVLYNLC
                     ESIRIIATLINPIMNETANKIYEHIGIKGQDDITTWESTKTFGLIGENVKVFKGEPLF
                     PRLDVEKEIEELTKMFSGKPPVEEKPLEHKEEITIDDLDKIELRVGKIISCEKHPKAN
                     KLLVSQVKIGPETRQIVSGIAEYYKPEDLVGKEVTVVCNLKPVKLRGVESQGMILAAG
                     DDGDPYVLPFTQGAKDGCEVR"
     gene            12596..13366
                     /locus_tag="PC512_000014"
     CDS             12596..13366
                     /locus_tag="PC512_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HDF2439794.1"
                     /translation="MLFDSHAHLNDESFDEDRDELIGSLKDKGVDLVVNPGADIETSI
                     TAIELAKKYDFIYSAVGVHPHDVSKLDDTAIETLRKLATENEKVVAIGEIGLDYYYDY
                     SPREEQKEWFKKQIELANELKLPIIIHDRDAHGDTFEIIKNTKNPEIGCVLHCYSGNV
                     ELAREYVKMGCYISIPGTVTFKNNKKTREVVREIPLERLFIETDSPYMSPEPHRGKRN
                     NPSQVSFVADKIAQEKGISYEEVCRVTKENAKKFFNIK"
     gene            13703..14134
                     /gene="phnG"
                     /locus_tag="PC512_000015"
     CDS             13703..14134
                     /gene="phnG"
                     /locus_tag="PC512_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnG"
                     /protein_id="HDF2439795.1"
                     /translation="MYTVDSTKILINMNLEKLEKIYSMIKDTSSISIIKEPNLATVMV
                     RANESVKNTTFNLGEILVTECSVKVDESLGYGIVSENNNKKAIYLAVIDAVLHSNNSK
                     FDELKNYINKSVYEENLRYEQEIIDEFSLINKTKVQFNAMD"
     gene            14149..14724
                     /gene="phnH"
                     /locus_tag="PC512_000016"
     CDS             14149..14724
                     /gene="phnH"
                     /locus_tag="PC512_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnH"
                     /protein_id="HDF2439796.1"
                     /translation="MVNYTQEIYRKMLDSASFPGKLNNIDNINIENNTKLLNGAIGIA
                     ITLLDQEVTFYIENYTQKDIKNIRALTMSNQIDYRKSDYIFLDINSEVDILQIKIGSF
                     EYPDESATIVHQVNDLSTYSQTKYIKLDLSGPGIKSKNSIYINGIREEFIERLSSINK
                     DYPIGIDLILVDKKGEIAFIPRSSKLSWEVL"
     gene            14727..15812
                     /locus_tag="PC512_000017"
     CDS             14727..15812
                     /locus_tag="PC512_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-phosphorus lyase complex subunit PhnI"
                     /protein_id="HDF2439797.1"
                     /translation="MAYVAVKGGEEAILQAKNILEFYRVKGDSLPIDVKQIEEQMSYA
                     VDKVMSEGSLYNKELSALAIKQAQGDILEASFYVRALRSTMPRITYSEPINTEEMRIK
                     RRISATFKDIPGGQYLGATRDYENRILNVELLEEDEKKNRHFRDSFINELETVDEIPE
                     FTKISNIFRKENLLQEEVCENKLEEVIDDITRNSLRFPVSRSAKLQALTRGESGVVSG
                     FAYAIVRGFGDEHPYISELRTGNVFIKVKHPIYEDEEIIIGDMLVTECEIVSKASQNK
                     TENSKTNSEDKNKMSLGYGLCMGNNENKAISMAILDKSLEPNSEKLAQDEEFVLLHID
                     GIDSLGFISHFKLPHYVDFKADVERIK"
     gene            15832..16701
                     /locus_tag="PC512_000018"
     CDS             15832..16701
                     /locus_tag="PC512_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate 5-phosphate
                     C-P-lyase PhnJ"
                     /protein_id="HDF2439798.1"
                     /translation="MIYNYGFLDENTKKEIRRKILKAISIPGYQVPFGSRELPIAKGW
                     GTGGLQLTLSLIGKNDVVKVIDQGSDDSTNACNIRSFIASVSNVETTKDTLEATLIQT
                     RHRIPEEKLKSNQILIFQVPIPETLRIVEPSEVETRRMHSEEDYSRMWVYLYEDIVRF
                     NDISIAVEYPCKVNDRYLMNPSPIPRFDIKKLNMSDNLFLFGAGREKRIYAIPPYTKV
                     EPLEFEDYKFEEEKFEGKYCSLCNSTNTFLDEVYDSDTNEKYYSCSDTSYCEKVRLKN
                     NSIDVTIGGTWNE"
     gene            16694..17560
                     /locus_tag="PC512_000019"
     CDS             16694..17560
                     /locus_tag="PC512_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2439799.1"
                     /translation="MSKINDSKRLENIDKQVLIGRNINLIYGDGCEKCFESTGYESNN
                     ICKYCGSIVACNNVNLELYEGEVLGIVGESGSGKSTLLKILFFQEHANSGEVYISHYN
                     KDTNILELSDQKKRYIKNHFMGIVYQNPHLGLNLDFSSGGNIAEKLLMANLYNVEKIR
                     DRGKELLIKTNIPVERIDHKPKYFSGGMQQRVQIAKALSNNPPILLLDEVTTGLDVSV
                     QAEVLDLIREIQRELKISMIVVSHDFDVIKMLADRTIVMKNGSVIESGLTDQIMEDPQ
                     HPYTQQLINSLL"
     gene            17601..18314
                     /locus_tag="PC512_000020"
     CDS             17601..18314
                     /locus_tag="PC512_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2439800.1"
                     /translation="MKETILEVNNFSKDFELHALNKTITACSNISFEVSKGEFLGIIG
                     KSGAGKSTILKSIYKTYIPTTGEIIFNSEIYGNVDLAKIGDREMINLRKKEIGYVSQF
                     LKTLPRITAIELVVHSLIESGFEKDCSYDMAKDILNQFEIKENLWDAYPNNFSGGEKL
                     RLNLAQAMVKKPRLLLLDEPTASLDNQSKIYVKEKMLELKSQGTTMIGIFHDIEFMET
                     VIDKTFTMTKGTISESGVA"
     gene            18315..19484
                     /locus_tag="PC512_000021"
     CDS             18315..19484
                     /locus_tag="PC512_000021"
                     /EC_number="3.6.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate
                     5-triphosphate diphosphatase"
                     /protein_id="HDF2439801.1"
                     /translation="MIKLIHNANIVLEDMILENGHLIIEGDTIKKVSNDKIDYAFDFN
                     EIDEIIDAKNLYVIPGIIDIHSDAIEKEIEPRPSTLLPFNMAFYELDKKLPANGITTV
                     YHSISLGDGVGVRSIDNSLKMIKNIDSYKNIDSKSINHKVHLRYEVLYYEGLEKVLEL
                     LDENKIDYLSIMDHSPGQGQYTNPTFYKEYATKVWGVTENYVDTWLDDLVNLHDNLDW
                     NKIANIIGIAKTKNINVASHDDDTLEKMDFIKNIGINVSEFPITLEVAKHSKKLGVLT
                     CLGAPNIVRGKSHNNNLKAMDAILEDCCDIVCSDYLPSAMIKSMCIVAERINNLNKAV
                     SLFTSNPAKAVGIYDERGSIKENKKADLVLVDIDSEYPKVVNTIVNGKTVYKREV"
     gene            19488..20324
                     /locus_tag="PC512_000022"
     CDS             19488..20324
                     /locus_tag="PC512_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HDF2439802.1"
                     /translation="MLTELHCHTSISDNNFTTEEIIKKAAEKNINILAITNHDTLSGL
                     DEALVLGEHYGITIIPGIEISAYDYKNRKRVHILGYNIDLNSQEIKNLCNPMVCDRHK
                     ASVKMVNKIIDLGYKISLEDVKKYSSKTGIFKQHIMKALIDKGYTDNIYSNLYKELFH
                     RGNGKVYVSLKYVDYRDAIKAIKNSGGICVLAHPGQMDNFSAIEEMVKVGLDGIEVYH
                     PSHNKELEKESLSYAKKYNLVVTGGSDYHGFYSQHNYELGSKSLNKEDLFKFRLALGG
                     VL"
     gene            20325..21320
                     /locus_tag="PC512_000023"
     CDS             20325..21320
                     /locus_tag="PC512_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2439803.1"
                     /translation="MSFLQVKNVGKSYGQVKVLKDISIDIEKGEFICLLGPSGCGKST
                     LLRIIAGLEDKHGGKIIINDKDMTNSPPESRNFGIVFQSYALFPNMNVYKNIAFGLEN
                     KNISKSNIDKKVKEVLEVVELSGYEKKYPSQLSGGQQQRVALARAIALEPDFLLLDEP
                     LSALDAKVRLKLREQIRSLHRKLGITTIMVTHDQEEALCLADKMVVMNRGEIIQVGTP
                     KEVYKNPETPFVADFIGTINFIDDGINKIAIRPEDIKVESNRDSKDKDIKVGEILDIE
                     FRGFNYRITVEYRSKQMKLDVVSKVAEQMKLCIGSKINFKIPKEGIVQYKSEGCA"
     gene            21338..23026
                     /locus_tag="PC512_000024"
     CDS             21338..23026
                     /locus_tag="PC512_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     permease subunit"
                     /protein_id="HDF2439804.1"
                     /translation="MITSKNKRRISDSTIQKYFLIFSVIVLIVFILFPLVSLLKNAFM
                     DTSGNFIGISNFSKYVENPSLIASFKNSIFVSTVSSLISLCLAFIYSYAITRTNIKFK
                     DFFKTMGMFPLFAPTMLYGISLIYLFGNKGIFTTMGLEVPLYGPLGIIISQILFTFPQ
                     AFLILSVALSMADYRLYEAADSLGASEFKKFCKITIPGIKYSLLSSFFVSFILAFTDF
                     GAAKVVGGNYNVLATDIYKQVVGQFNIPMGATVSMVMLIPVLIAFTLDKMASKKQGMT
                     ITAKSMPYKIKENKFRDRVFLIVCSFITLLIFILIFVSVIGSVIKLWPYNLSFTMEHY
                     TFKGILGSGIKTYLSSLKISTLTAIFGTIFVFFSAYMIEKVDKFPKLRQTAYLLSMIP
                     MALPGLVLGISYITFFNSASNPLNFLYGSTAILVIVNVVHFYSVCFITSNSSLKMLDK
                     EYELVAKSINIPFYKVFFNITVPMSITSILEIVVYYFVNSMVTVSALIFLYTPQTQTA
                     SISILKLDEIGYIGTSAAMAVLVLLTNIIVRLLYEFVTKKLKNNTQKWQQKDVA"
     gene            23038..24105
                     /locus_tag="PC512_000025"
     CDS             23038..24105
                     /locus_tag="PC512_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF2439805.1"
                     /translation="MKFKKLVSLGVLSTLLLSVITGCSTDSSGSDSKSDSKTKGDLTV
                     YTAIEEDSIEPYLATFKEKYPDIKLNIVRASTGDITARLLAEKDNPQADVVWGVAATS
                     LLVADDQGMLEPYAPKGSEEIESAFKDDKEVPSWVGIDAWMTGITVNTKELSDKNIPV
                     PSSYEDLIKPEYKGLISMPNPSSSGTGYLTVSALIQIMGEEKAWQYMDKLHENIGVYT
                     QSGSAPATSAASGEYPIGISFGYRGIKLKEEGYPVEVVFPKEGSGWDIEANALVKKDN
                     IKEASKVFLDWAISKDVMNEYSKNYAVTTISTGNPIPEGFPKKPLEQMIDNDLKSAAK
                     NREDILNKWISKYDGKTEKES"
     gene            24542..25537
                     /locus_tag="PC512_000026"
     CDS             24542..25537
                     /locus_tag="PC512_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2439806.1"
                     /translation="MSFLQVKNVGKSYGQVKVLKDISIDIEKGEFICLLGPSGCGKST
                     LLRIIAGLEDKHDGKIIINDKDMTNSPPESRNFGIVFQSYALFPNMNVYKNIAFGLEN
                     KNISKSDIDKKVRDILEVVELSGYDKKYPSQLSGGQQQRVALARAIALEPDFLLLDEP
                     LSALDAKVRLKLREQIKSLHRKLGITTIMVTHDQEEALCLADKMVVMNNGEVIQIGTP
                     KEVYKSPKTPFVADFIGTINFIDDDVNMIAIRPEDIKVEFNRDFKEIDVKVGEILDIE
                     FRGFNYRITVEYCSKQIKLDVVSKVVEQMKLCVGSKINFKIPKERTIQYKSEGCA"
     gene            25555..27243
                     /locus_tag="PC512_000027"
     CDS             25555..27243
                     /locus_tag="PC512_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     permease subunit"
                     /protein_id="HDF2439807.1"
                     /translation="MITIKNKRRISDSKIQKCFLVFLVIALVVFILFPLISLLKNAFM
                     DTSGSFVGISNFSKYIENPTLIASFKNSIFVSTISSLISLCLAFIYSYAITRTNIRFK
                     NFFKTMGIFPLFAPAMLYGISLIYLFGNKGIFTIIGIEVPLYGPLGIIICQILFTFPQ
                     AFLILSVALSMADYRLYEAADSLGASEFKKFFKITIPGIKYSLVSSFFVSFILAFTDF
                     GAAKIVGGNYNVLATDIYKQVVGQFNIPMGATVSMVMLIPVLIAFTVDKIASKKQGMT
                     ITAKSMPYKIKENKFRDRVFLIACSFITLLIFILIFVSVIGSVIKLWPYDLSFTMEHY
                     TFKGISGNGIKTYLSSLKISILTAIFGTIFVFFSAYMIEKVDKFPRLRQISYFLSMIP
                     MALPGLALGISYITFFNSASNPLNFLYGSTTIMVIANIVHFYSVCFITSNSSLKMLDR
                     EYELVAKSINIPFYKVFFYVTLPMSITSILEVAVYYFVNSMVTVSALIFLYIPQTQTA
                     SISILKLEEIGYIGPSAAMAVLVFLTNIIVKLLYELTTKKLKTKTQKWQQKEVA"
     gene            27255..28322
                     /locus_tag="PC512_000028"
     CDS             27255..28322
                     /locus_tag="PC512_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF2439808.1"
                     /translation="MKFRKLVSLGILSTLLLSVITGCNNASSGSNLKSNNKIKGELTV
                     YTAIEEDSIDTYLTTFKEKYPDIKLNVLRLSVGDITARLLAEKDNPKADVLWGVAATS
                     LIILDDKEMLEPYAPKGFDKVNPVFKDDKKVPSWVGIDAWMTGITVNTKELSDKNIPV
                     PSSYEDLIKPEYKGLISMPNPASSGTGYLTVSELIQIMGEEKAWQYMDKLHKNIGVYT
                     QSGSAPAILAASGEYPIGISFGNRGIKLKGEGYPVEVVFPKEGSGWEIESNALVKKDN
                     IKEASKVFLDWAISKDAMNEYSKNFAVTTIDTGNPVPEGFPKNPLEQMIDNDLKSAAR
                     NREAILNKWIEKYDGKTEKES"
     gene            28514..29044
                     /gene="rnmV"
                     /locus_tag="PC512_000029"
     CDS             28514..29044
                     /gene="rnmV"
                     /locus_tag="PC512_000029"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HDF2439809.1"
                     /translation="MIKEIIVVEGRDDVTAVKRAIDAELITTGGFGFPKGVMERIKAA
                     NERRGVIIFTDPDFAGEKIRKKIASEVPGCKHAFLPREEAKKDGDIGIENATPQSIIA
                     ALNKVRTENTEKRDEFKQVDLIRNGLIGNEEASLRRDALGKILGIGYGNAKQFLNRLN
                     NYGVEREEFIDALKQI"
     gene            29215..30084
                     /gene="rsmA"
                     /locus_tag="PC512_000030"
     CDS             29215..30084
                     /gene="rsmA"
                     /locus_tag="PC512_000030"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HDF2439810.1"
                     /translation="MDRLSSHNATKEVVQKYNFKFSKSLGQNFLIDSNIIDKILSGAR
                     ITRGDNIIEVGPGIGTLTREMGKIAEKVVAIEIDRNLIPILKDTLSDLDNTEVVNQDI
                     LKVDIQELVKDKLNGGPVKLVANLPYYITTPIVMKFLEEDIPVTDIVVMVQKEVADRM
                     NAIPGTKDYGALSIAVQYYCDTEIVAKAPRHMFIPQPNVDSTVIGLHVRDKRKYDVHN
                     EDIFFKTVKASFGQRRKTLLNSLGGLGFLNKDEIREVLKEANIDEKRRGETLSIEEFS
                     VLSNIINTKVSSK"
     gene            30150..31415
                     /locus_tag="PC512_000031"
     CDS             30150..31415
                     /locus_tag="PC512_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2439811.1"
                     /translation="MGSKRKFKRDYIILEAKDINFRYKERVLPKAFAKVEVNDEKAII
                     ALYVENLKYVKDGYKAVAIKDDHGLIDLGNIILNEQGRGEFVLDLEDYDDEIKGIALL
                     YERNIPLIGFKGNKLENYEDILFQEVEEEEYEEYEELEEEDEEIEDNEESDRDEGSEE
                     EYIIEEYDEDEYEDYWEDDEDIDEGELKARTEVEDSGDEEIEEFNNYKEIENYNRVKV
                     QEEYIDIEYDEEEEEEEEVFEVNREEDRFVSSKPTKSKKVQKDQNNIEKIKRANGVSQ
                     GESGNKQTSTLLMPRQIKKGLKLFKEVKPFVTDYIDKTRWWKIEINPTTLCGYTMPYL
                     GYLNVLNYTMYSDAVLHSYKYRHYLFGVQYDEYNKRKHYIYAIPGNRNEQPDNGSTGF
                     LRYQACDNRTNSLGYWLCFIDSRQRNIVR"
     gene            31566..32681
                     /locus_tag="PC512_000032"
     CDS             31566..32681
                     /locus_tag="PC512_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HDF2439812.1"
                     /translation="MINEQRILNEFLELVQIDSLSLKEGNVAKVLVKKLEEIGCSVVI
                     DNAGEKANGETGNIIATLKGNKEGKKILFSSHMDTVTPGIGVKPIVDEANGIIKSDGT
                     TILGSDDKAGIAAILEGLRYINENNIEHTDIQVVFSICEECGLVGAKNLDYGKIDSEY
                     AFILDSGGSPGEIIVKAPAQDVINVKILGKTAHAGLEPEAGISAIMVAARAIENMNLL
                     RIDEETTANIGIINGGTATNIVTGEVNIIAEARSLKENKLDVQTKHMVETFEKAAKDF
                     GAQIEIDVNRAYTPIDVSEDSEIIKLAKKAFSNLGIEGHTESTGGGSDTNILSKNGIE
                     AITLGIGMKNAHTLSEHIAIKDLYDSAKMVVEIIKEA"
     gene            32867..33763
                     /locus_tag="PC512_000033"
     CDS             32867..33763
                     /locus_tag="PC512_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HDF2439813.1"
                     /translation="METRYEEANKITIQSILWNVVLTIIKVIAGVIGNSSAMIADGLH
                     SASDIISSIGVLIGNYVSSRPGDREHNYGHEKAETLVSFVLSILLIFVSITIGIEAIK
                     SLFNLDALSVPSILPLVVSVISILIKEYQYRITIKVAKKINSPALKADAWHHRSDALS
                     SVAAFIGIGGSILGFKPLDPIASVVVAIFVAKVGISILISSVNELMDVSVDEEEIKEL
                     KFIVADTEGVKNLGDIKTRKHGAMAYVDLTICVDENLTVKQGHDIATKLEKHIIKHME
                     FVKGITVHVEPCTNCQGNKCNN"
     gene            33833..34630
                     /locus_tag="PC512_000034"
     CDS             33833..34630
                     /locus_tag="PC512_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2439814.1"
                     /translation="MSKKRKLKKKAAILIGVVVFFIIYFISFRIGINMEKDKSEVPKK
                     VEKEEEDNRSLRTQIKEKKKVYISDKNIENIKIEEDMWDEIKLFFSDFKKVRNTTSSY
                     EAVYEGYSDDGVKFSTDLNFFRVYTVNKEEYYKVPVSSKDAFKKLLDESIYTSFDLLS
                     HYKDWKEVTITHGKEIKKVHRWKFDDLAHKMISKRVVGKVQPEKSKERSDYNFTINIK
                     GDNFDVKVDTMGKDYVKVTSKKNVSYYEVHTSLFDYLKNEIFEIGKK"
     gene            complement(34685..36037)
                     /locus_tag="PC512_000035"
     CDS             complement(34685..36037)
                     /locus_tag="PC512_000035"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HDF2439815.1"
                     /translation="MNIHFIGIGGISMSALAEICINKGYQVSGSDSNESYLLDKLRDQ
                     GATIYIGQKKDNISDDVNMVVYTAAVHPDNEELVAAKEKNKLVMNRATFLGQIMREYK
                     NSIAVSGTHGKTSTTSMLSTIFEYADLDPTILVGGNLSMIGGNVKIGNSNHFITEACE
                     YVDSFLNFNPKISIVLNVEEDHLDYFSGIDEIKASFNKFGKLLPPEGYFIINGDDENI
                     DDILYDVKATIIKYGRDSDNDAVIKDIHFDNSGHGIFRIEYEGRDLGEFELSVYGLHN
                     IYNASSAIMAALVSGIDLETIRKNIKIYKGVGRRFETKGYYKNALVVDDYAHHPTELK
                     ATLAAAKKLKKSTLWCIFQPHTYTRTKSLLGEFSEAFYAADKVIITDIYAAREKDPGD
                     IHSKDLVEKLYQNNVDAIYIKEFEDIVKYLRENVKDNDLVITAGAGPIYKVADLLVEK
                     "
     gene            36256..37134
                     /gene="purR"
                     /locus_tag="PC512_000036"
     CDS             36256..37134
                     /gene="purR"
                     /locus_tag="PC512_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HDF2439816.1"
                     /translation="MKFKRTERIGAIVKILSDNPNKIYTLSYFTNQFNAAKSTISEDL
                     LVVKNVFEKLHLGKVITISGAAGGVKYIPKTSIAENAEFLMELCERICDKSRILSGGF
                     LYLIDLIYDPTIAAKIGKIFASNIEYVDADYVVTMETKGIPMALMTAKAMNLPLVIIR
                     KDIKVSEGPTLSMTYVSGNSSKVESMSLPRKALKPDSKVIIIDDFMRGGGTIKGMVDL
                     MNEFGAEVIGTGVFISTTNPSEKMVKDYISLIQLDVNGDKIVVEPNLKTFKDEYRNED
                     LDEEEDSEFEFEIDED"
     gene            37290..37568
                     /gene="spoVG"
                     /locus_tag="PC512_000037"
     CDS             37290..37568
                     /gene="spoVG"
                     /locus_tag="PC512_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation regulator SpoVG"
                     /protein_id="HDF2439817.1"
                     /translation="MKITDVRVRKLTEEGKMKCIVSITFDNLFVVHDIKVIEGHNGLF
                     IAMPSRKVGEGNFRDIAHPINAEMRQVLEDAVLQAYHEALVQWEVAAE"
     gene            37781..39160
                     /gene="glmU"
                     /locus_tag="PC512_000038"
     CDS             37781..39160
                     /gene="glmU"
                     /locus_tag="PC512_000038"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HDF2439818.1"
                     /translation="MNFKAIILAAGKGTRMKSKYPKVIHKVCGKEMVNHIIDVSKKSG
                     VKDTVVILGHEADVVKEKLAEEIIIAMQTEQLGTGHAVKMAKEYINDEDTIVVLCGDT
                     PLIKEETLKRLFEYHIENKYHATVLTTRVGNPTGYGRIIRDKKGDLLKIVEQKDANSE
                     EKMISEINSGIYCFNGKSLREALDLLNNNNSQGEYYLTDTAKIMRDKGLKVGAFAGST
                     IEELMGVNSRVELSKAEEIMRRRINESHMVNGVTIIDTNSTYIESDVMIGNDTIIYPG
                     VMLQGKTRIGSDCIIGMNSSITNSEIGDGTEIKNSTIIDSKVGENSTVGPYAYLRPKS
                     DLGNNVKIGDFVEVKNAIIEDGSKASHLSYIGDAHVGKNVNIGCGVVFVNYDGKNKFK
                     SIVKDNAFIGSNSNLVAPVVVEEKGYIATGSTITHDVPDGALAIARERQVIKEGWVEK
                     KNQKDDQSK"
     gene            39255..40205
                     /locus_tag="PC512_000039"
     CDS             39255..40205
                     /locus_tag="PC512_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003361732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate pyrophosphokinase"
                     /protein_id="HDF2439819.1"
                     /translation="MNTSGSEIKIIAGNSSKELAQKIADYIGVSVLDCEVGTFSDGEI
                     CVNMNETVRGCDVFVVQSTNSPVNDNLMELLILIDALKRASAGRITAVIPYYGYARQD
                     RKAKARDPITAKLVANLITAAGADRVLTMDLHAAQIQGYFDIPLDHLLGGTILANYFN
                     EKKIEDLVVVSPDLGSVTRSRKFANTLNGEVPIAIIDKRRPKANVCEVMNLIGDVKGK
                     NVILLDDMIDTAGTIVNAANALKEFGAKDVYACCTHGVLSGPAIERIANSEISELIVL
                     DTIQLPEEKRIDKIKIKTVAPLFGDAIRMIFSNESVSKLF"
     regulatory      41049..41134
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            41296..41817
                     /locus_tag="PC512_000040"
     CDS             41296..41817
                     /locus_tag="PC512_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HDF2439820.1"
                     /translation="MKLKKNKKGFTLVELLVVIAIIGILAVVAVPALFSNINKAKVAS
                     VESDYSSVKSAALSYYSDTNKIPVTTTDKAGLTILETYMESLPDKADIGGKYKLIKVG
                     NKLVLQIGTDTEGVTLTEAQSAKLLSDIGKDKIYTGVTGDNFGDELTDTTKIDNKALY
                     IVLIDNTVMDSTK"
     gene            41969..43645
                     /locus_tag="PC512_000041"
     CDS             41969..43645
                     /locus_tag="PC512_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HDF2439821.1"
                     /translation="MAKKVRIGDKLVEKGYITEEQLKWALSEQKNSGKRLGEFLVQEG
                     LIDSNLLISVLKELLDIESIFLEGTEIDTLATKMVPENICKRYTVFPFKIDGNKICLA
                     MSDPQDREAVQDVRRMSGKDVEIFISSTEDINKAIGHAYAHSEINKAMTEYNKNRTGG
                     VRETVILEEDVNAAPIVRLVNNILENAVRMEASDIHIEQSENYMRVRFRIDGMLREYM
                     RMNSAPYKAVISRIKIMSDINISEKRIPQDGRIYLKVDNKPIDFRVSTMPTNRDEKIA
                     MRVLDKSNFMVSKEVLGIDEHGSKIYDELINTPYGLILVVGPTGSGKTTTLYSMLNQL
                     NTENRNLLTIEDPIEYELPGVNQSQINEKAGLTFASGLRAFMRQDPDIIMVGEIRDTE
                     TAEIAIRASLTGHLVLSTLHANTAVGAISRLLDMDVESFLITSSVLGVISQRLTRKIC
                     EHCKVSYEADIGEKKALGIDVNESVTIYRGKGCERCNNTGYKGRLGIFEMLEITPEIK
                     ELIDSSANQREILKMARKQGMVSLKEDIVKKVLNGKTTVEEMIRIILMTD"
     gene            43657..44865
                     /locus_tag="PC512_000042"
     CDS             43657..44865
                     /locus_tag="PC512_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HDF2439822.1"
                     /translation="MKSFKYTVIKEDGKKQTDVIEANDFNEARNLLRKRNLRVIEIKE
                     SKNKNIRLSSRKRKKDLGADQISHFCRQFAIIVSSGINSISGLETLARRSTNITLREE
                     INRIVAEIKVGSTIADSMLSSKSKFPKLLGAMVATGEATGKLDEVLKSMASFYASEHR
                     VKQKLRNAATYPLIVLISSFIMIFIFTTFMVPKMINSITTVGATLPLITRIVMGFGMF
                     MKKFWIIVLLVIILFIYQFKKYLKTSVGRAHKDRVINKIPVLGKGINCMVATRFSRAL
                     YLFVSTGYPLVQGLDYIIDSVNNTMAEKILASAKDGITRGEGLAENLERYTYFDSVLV
                     QMIAIGEQTGELENISRQMAEFYEYESEIYLNRMASMIEPVLIIAVGIIVAILVVSIF
                     MPMLSIYDAM"
     gene            44880..46592
                     /locus_tag="PC512_000043"
     CDS             44880..46592
                     /locus_tag="PC512_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilN domain-containing protein"
                     /protein_id="HDF2439823.1"
                     /translation="MNKVYVSYYGDSISIVEGRYKHDKDKFYVKNFNVFSIEDIAQDF
                     SKEKYALLRYALENVKLKSRHVVFCLNTRDVILKPQKLPNMDKKDLDGFMKLEMDEMM
                     ALESDEYVFSYEVSSETPDNSDGDESSLNLIIGAIQKEEVNAIVEIMHEFDLVLDRID
                     TLSTAYLRMLKNLDYNDIMVTNISDNSTIINIYKKDTLFISDNIPIKITAKDMDMQLL
                     NVVEESKGLMNYYSSRNFGKVTDTILILGKRYSNKLIYETFSSAFSSYVSQGLTEIMD
                     ISDMITGDIDEDDINSIVELLGSMIEPKGKRDFENINFLPMDILRKQIKAKQMKNILK
                     IAPIVILILAIPYLCLIFSNNLANKELENVNGEIRNIESAYYQIGNIEKMIQSKSEEI
                     KVYDMLIGKKVKWENLLDDIDKNTPSKVELTSLSTTYQNLGTNNKADNSKSNKTTTDK
                     SSNNETKSSTKSDSNGDKTDNDLNEDKTTNVSEALTGNSETNSNNTDKDDKTPLYDKI
                     PNVINIEGNAKDSSYVGQFLYKLKGLYYFKDVKLHSIKSNAEDSNYTFSMTLYLKEGV
                     LTNE"
     gene            46585..47493
                     /gene="pilO"
                     /locus_tag="PC512_000044"
     CDS             46585..47493
                     /gene="pilO"
                     /locus_tag="PC512_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 4a pilus biogenesis protein PilO"
                     /protein_id="HDF2439824.1"
                     /translation="MNKDIFKKDIKDIFKMEVSLKGILIKVIILLAILSYGYFGLYPQ
                     YQKYIATKNSVKQATEKLNIYKEKTALMPKYEKQLEEVESELKEKSKNLLYDMQDGLF
                     LIGLDKKMKAYNIDLTSYDVGNVKEYEHFYGISTTISVRGDYRNVKKLMAYLEEQKNV
                     TQILDYTMTSYIEPEKEEEETTNNKDLIKNVNINKDTKIYWVEGENKWHLYKDCPLIK
                     EGEIIKNDKLLDRSTNYLCNTCVLRAATEKEAKKEVVAPKAEGVVDATFKFIMYTKEN
                     TTMILDTDNPSSWRPGKYNPFKSSAK"
     gene            47520..48086
                     /locus_tag="PC512_000045"
     CDS             47520..48086
                     /locus_tag="PC512_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HDF2439825.1"
                     /translation="MSLYKNNEKGLTLLEVIIAVFILTIVLSISYKVFNGITSAVKKQ
                     QIITDAQVNINLINKYLNRDLENCKELTKTGSGNNYEYNIEMPDNVVKYEVSIETKKN
                     TEVYSVTRIQNNTIDTENEVREEIIYNQPLVQNNKEMKETPFKIEKQTGKSIYTVSIY
                     YNESVQESHKNSNLNNKTYTFDVMSRIG"
     gene            48123..48650
                     /locus_tag="PC512_000046"
     CDS             48123..48650
                     /locus_tag="PC512_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HDF2439826.1"
                     /translation="MSKKNSERGFSLIEVLVAMAIMGIVLFAFFNIINTNNKANTKND
                     TDITSLNYVQSEIENLREKIKSGEFDFDSLDKLEDGTVVYEKLIDKSKKVVYDKVLSE
                     GDVSLYDTPYEKITTIKDEDGNLIDKGNITNKIKTIVEDKSGQIYKIAVTGKSMNDYS
                     SKKEVKIVTEIFKDK"
     gene            48671..50209
                     /locus_tag="PC512_000047"
     CDS             48671..50209
                     /locus_tag="PC512_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2439827.1"
                     /translation="MRKWNKFKSERGAALVLVLVVVALLSIVGLIFSNQIANRIKSTK
                     TTNEGIQAKYLAETCVENSIDKAYEKLYDELEKMDNEFKSENQEKSISRSKLRNISDE
                     DFNNQDEENIEAERLGYMNNINFYLNKASSDLEKASMELKKLYDLDMLDYRDIEYVDA
                     NIISHRNSILEICKNYTSGDISKINEYILKEDIDSTTLIEAKLVNNDILLKKFLEENK
                     IENEHLNSAFSHTYKALDNISLAMQNMIEYRHTFHIDEPKVEVSNGIPDSQQYYELIQ
                     NPIINSMEYSWNSKWDTLENLLEILPNQTQGFNSLRVHLRNNVRKFEKLSDNISSGKK
                     NTAKNFLKYKELLYEISDQCNQLKSMSYEKIPVKYDNMALITTFDYIQNELLAEIKCR
                     LKELKPQEIDKTEGITIKIPFYKADYDMTKEGWPKLKENGSGAELSLMVTGDKNGIKE
                     VEVTDGKKNIIGLGVEENSNSKYKVDAIVNFNLNIDTNVVGNYDIKDKILINHDISSY
                     KKVN"
     gene            50309..51391
                     /locus_tag="PC512_000048"
     CDS             50309..51391
                     /locus_tag="PC512_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus twitching motility protein PilT"
                     /protein_id="HDF2439828.1"
                     /translation="MYIYDLLEQGIRLNASDIHITVGTNPVARVKGGFVKLSEQILTS
                     EVTMQMAKDIAGESMFKVIEEHGEADFSASLKTGERFRVNAYRQKGNYAIAIRTITAE
                     IPTFEKLGLPESIKSFTEKHKGLVLVTGPTGSGKSTTLASMINIINEKQQKHIITLED
                     PIEYVHHHKQSLVNQREVGTDTESFHSALRAILRQDPDVILIGEMRDPETVSIALTAA
                     ETGHLVFSTLHTVGAAKTIDRIVDMFQPSQQQQIKTQLSTVCEGVVSQQLLPTADGKG
                     RIAAIELMFATPAIKNLIREGKTYQIPNMIQTGVKVGMKTMDQDLMELYKNGKITKDM
                     ALSRCTDQEFMTRMIGGVNYNGYYNR"
     gene            51372..52154
                     /locus_tag="PC512_000049"
     CDS             51372..52154
                     /locus_tag="PC512_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HDF2439829.1"
                     /translation="MDIIIVNLYVFIVGIVFGSFFNVCIFRIPEGISISRPPSHCMSC
                     NTRLKPIDLIPVLSYLMSGRKCRYCYEKISSRYAIVELITGLLFLTVFMLYGISTSTI
                     YYLVLVSLLIIITFIDIDHFIIPDKILVFGAIFSMIFNLLFKEIPVKDSILGVFICGG
                     SVWIIVLLIEFVIKKECMGGGDIKLFAMLGFYMGVKNGLLTALLSVYVGAVYGICVII
                     ISRIKGKEYNSVIPYGPFISIGALITILSGKQLLELYFSMVI"
     gene            52256..52906
                     /locus_tag="PC512_000050"
     CDS             52256..52906
                     /locus_tag="PC512_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HDF2439830.1"
                     /translation="MEYIIIISLFFAHLINKSLCVFCDREKKNLYNTFFIYIITVVLS
                     VLIYLKFGISVECVQYMVLIPFLIIISIVDYYTIYVYDITIVSGIIVQGIIFLAFFNI
                     VQFDYINHIFGLLIGFIIPYIIAKLTKGLGYGDVGLYSLCCFALGNNYGFYVIVLSFI
                     LAFLFFIILYITKIFKDVDIRKQIPFTPFISLSTILIIFTEYNIFNFYYNLLYKFI"
     gene            52920..53480
                     /locus_tag="PC512_000051"
     CDS             52920..53480
                     /locus_tag="PC512_000051"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HDF2439831.1"
                     /translation="MYVVVGLGNPGKKYEKTRHNVGFDVIDILAKEYNISVTKIKHKA
                     LIGEGRVGTEKVLLVKPQTYMNLSGETLIDIYKYYKVDLSNIVVVYDDIDLEVGKIRI
                     RKKGSGGTHNGMKSITKCLGSNDFPRVRVGVSKPEAGQDLADFVLSRFRKEESDNINE
                     ALEKAADAIDSIIRENIDMSMNKYNG"
     gene            53497..56883
                     /gene="mfd"
                     /locus_tag="PC512_000052"
     CDS             53497..56883
                     /gene="mfd"
                     /locus_tag="PC512_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HDF2439832.1"
                     /translation="MNDVFLYPLQNSKEYKDIINCIKNTKGSLLVNGLLPVQKPHISY
                     SIFNDLSRQMIFITSSDLEAKKVYEDLSFYMEDKVEYLGFQDIYFYHLDAKDRNEEAK
                     KLKVLLKLANKEKIILVTSIEAVLRKYIPKQVLLDSVSHYKVGDSLDLEKLTEKLVSL
                     GYERVSKIEGFGQFSIRGGIIDVFSLEYTNPIRMELFDDEIDSIRTFDVYSQKSIDKL
                     QQFSITPSREFIYPEKTTDALVKLKKETTKNTDEGTFQNIDYISSKTYFEGVENYIDY
                     IYPEENKSIFTYLADDAIVFINDITRLKERCENYINEFRENYKLNLERGLAIKNQGKL
                     LYHYTDLEYLVKDKSVVLNSLLPKSINNFSIKSIINFESREVPTFNGKVDLLVEELNR
                     LKYNGYKIILATNTLERANKLGKDLLDKGLETTISKDRDIEIKSSQVIIVPAHINSGF
                     QYKSIKFVVITDNEMIGVYKRASKTSNKKVKKGKKIESFLDLSVGDYVVHENSGVGRY
                     TGIEQITVNAIKKDYMKIVYQGGDNLYVPIDQMDKVQKYIGAEVEKVKLNKLGTNEWT
                     KAKAKVKKEIEDMTKDLIELYAKREKIQGYKFSKDTPWQAEFESLFPYQETEDQLKAI
                     EETKKDMESSKVMDRLVCGDVGYGKTEVAIRSIFKACMDQKQVAVLVPTTILAQQHYN
                     TFKERFENYPLRVEVLSRFKTPKQQKQIIEDAKKGLVDILIGTHRIISKDINLPNLGL
                     VVIDEEQRFGVKHKEALKKIKSTVDVLTLSATPIPRTLHMSLSGIRDMSVIEEPPQER
                     HPVITYVTESKESVIQDEIERELSRGGQVFFVYNRVEHIEEMASMIQKLVPDARVAVA
                     HGRMTSKSLENIILGFLNKDYDVLVCTTIIETGMDISNANTMIIYDADKMGLAQLYQL
                     RGRVGRSSRQGYAYLLYEKDKTLSEIAEKRLKAIREFTEFGSGFKIAMRDLEIRGAGN
                     ILGSQQHGHMAVIGYDLYVKMLNDAIKKVKGEPIVEEIDVEIDLSVNAYIPDNYIKDE
                     LIKIEMYKKIASIENKEDMLDIQEELEDRFSDIPKPVQTLLTIAYIKSLCKILKIEKI
                     RQLKDEILLVPITKYRTKQKIGYNIVTELEELLEKMCKVK"
     gene            56914..57909
                     /locus_tag="PC512_000053"
     CDS             56914..57909
                     /locus_tag="PC512_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDF2439833.1"
                     /translation="MKKVITLVIAMILVVSVTACSSSKGETVATVEGTKISSDEFKKT
                     IALYKDSMEQTYGKDIWDKEVEKGVKYKDKFKDLILDQLITTEVIYSQAKKDNLLPKK
                     EDVEKSFKELKDAMGKDEKYKEQLKKLGIDDEFLRDQQEKDLAMQNYQSNFAKKTKIS
                     DEEMKKYYDTHKDEFKKDEVEASHILLKTVDDNNKPLSDKEKAEAKKKAEEALKEVKS
                     GEDFAKVAKKYSQDTSASDGGKLGFFSRGQMVAEFEDAAFSMKKGEVSDLVETQYGYH
                     IIKVTDRINEQTSFEDAKETIKDQLLKNKYQEQIEKLTKEAKVEKDEKVINKITI"
     gene            58033..58572
                     /gene="spoVT"
                     /locus_tag="PC512_000054"
     CDS             58033..58572
                     /gene="spoVT"
                     /locus_tag="PC512_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein T"
                     /protein_id="HDF2439834.1"
                     /translation="MKATGIVRRIDDLGRVVIPKEIRKTLRIREGDPLEIFTAKDGEV
                     ILKKYSPIGELNEFSQEYAETLAEVLGYGVLITDLDSIIAVSKLPKKDYKEKSISDEL
                     EAIISERTVKYSKDKNILPLFKEDQKEYTSQVIMPIISASGDCIGSIVVVSKDKDTIA
                     ESEEKSLKIAANFLGKQVQ"
     gene            58692..60305
                     /locus_tag="PC512_000055"
     CDS             58692..60305
                     /locus_tag="PC512_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HDF2439835.1"
                     /translation="MNNNKNKDSFLKGALILGLAGVIVKIMGGFFRIPLGNMIGSEGM
                     GYYQAAYPVYTLFLTLATAGFPTAVAKLVSEKVAIGNFKGANKIFKVSHTVLFITGII
                     SFCILFFGADYIVTNVMKNPGALYSMKAIAPALLFVPAMSAYRGYFQGRQDMTKIAVS
                     QVAEQFFRVVLGLTLAYLLMKSLGQTFGAAGAISGATIGSIASMLYLVFAYMLGRKER
                     RAEIDASQRFKDERVSYIFKKLLTVAIPITIGASVMPLVNMIDNVIVIRRLMEAGFTY
                     KVANSMFGQLTGMAMATINLPAVITTAMSMSLVPAISKAYALGNKSKARKDTKSAVKV
                     TLLIVLPCAFGMASLAIPIMGLLFPHEPSSVGTILFTLTPCVLFLGLIQTLTGIIQGM
                     GKPIVPVIALCVGMLCKIVISYTLTGIPDINVLGSAFGTVTAYFVAAMINLLYVKKHM
                     NVNFSKKEFIIKPFITVMTMFIMVKLSYGALVGFLGNSISTIIAICVGGIVYVVVILG
                     IGGIKKEEILTMPKGDKLYKLLKKVKLIR"
     gene            60412..61860
                     /gene="mazG"
                     /locus_tag="PC512_000056"
     CDS             60412..61860
                     /gene="mazG"
                     /locus_tag="PC512_000056"
                     /EC_number="3.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphohydrolase"
                     /protein_id="HDF2439836.1"
                     /translation="MGKISIVGLGPGDYSLISQGVLESLINSPKVFFRTEKHPIIDKL
                     KETIQYTSLDYFYEKEENFDNVYLKISEFIIEESAKGDLVYAVPGHPRVAEKTVSIIE
                     RLANEKHIAVEILPSMSFVDAMFNYLAIDPSEGFKLVDAFEIENSYIDLDTSMIITQV
                     YDKFIASNVKLKLMEHYDYNQEVCIVNGAGVKDLESKKFIKLCELDRNENFFDYLTSL
                     YIPKSSKKMYNTVHDLEIIVNTLRSPSGCEWDKKQTHQSLKNSVIEEAYELCNAIDNN
                     DIDEMVEELGDVLLQVIFHCQIGNEEGYFDLKEVVNGICKKLIHRHPHIFSGAKLDMS
                     KFEKTWEELKKEEKGESTITDGLRRIPKHLPALMKASKVQHKAALVGFDWDNVEDVFK
                     KIEEEYQELLDEHRVGNIKYIKEELGDLLFSIVNLARFLDIDSGEALNCTTEKFINRF
                     DFIEKSAMNLNKKLEDMTLEEMDEFWNQAKKQ"
     gene            61949..62227
                     /locus_tag="PC512_000057"
     CDS             61949..62227
                     /locus_tag="PC512_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003153447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HDF2439837.1"
                     /translation="MNKAELVSKMAEKSGLTKKEAEAALNAFMSSVQDALVNNEKVQL
                     VGFGTFETRERAARQGRNPRDPEQVIDIPASKAPVFKAGKGLKDIING"
     gene            62299..62541
                     /locus_tag="PC512_000058"
     CDS             62299..62541
                     /locus_tag="PC512_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HDF2439838.1"
                     /translation="MRLDKFLKVSRIIKRRTVAKDACDKGIVTINGKVAKSSSEVNIG
                     DTLEIQFGEKKMKFKINEVKEHVLKNDAKEMYKILE"
     gene            62603..62857
                     /locus_tag="PC512_000059"
     CDS             62603..62857
                     /locus_tag="PC512_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YabP"
                     /protein_id="HDF2439839.1"
                     /translation="MEQNITLKDRSKLVISGVEHIYSFNDKRVELKTSVGEMVIEGEN
                     LDMSKLSIDENIISIDGTINSMVYAKPKKPQESFLKKVFR"
     gene            62858..63391
                     /locus_tag="PC512_000060"
     CDS             62858..63391
                     /locus_tag="PC512_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2439840.1"
                     /translation="MIPFTQDVSIFYATIYGGILIGVLFDFYRGLRGNFKFINYFAII
                     FDVLFWFLATVIIFVTINLTEFFDLRYYHFVALFIGFILYYNTISKIVLSIINKIIRF
                     VRNSFKKVTHYIVSFLNNLYYVIIYSLHLLFDIIFYIPNIFIATRKSIKRKSNKKLKN
                     KKKSKPKKKKNKTKKRV"
     gene            63397..63681
                     /locus_tag="PC512_000061"
     CDS             63397..63681
                     /locus_tag="PC512_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HDF2439841.1"
                     /translation="MNLRKKFSGQIIVISLFLGISIFSMMTGFVFEYTKAKEYKKEIA
                     SLNKQLKKTEIQINSLKKDEKSYEGDLEDIARKRLNMVKPNETVYVDINR"
     gene            63794..64714
                     /locus_tag="PC512_000062"
     CDS             63794..64714
                     /locus_tag="PC512_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ppx/GppA family phosphatase"
                     /protein_id="HDF2439842.1"
                     /translation="MKVGAIDIGTNSMRLLIADYRDGNFINRKKFVNTTRIGYGVDSK
                     GYIKEDAIKRNIKALKEFSDKCNDEKCEKIYCMGTSALRDSKNGDYFVKLAKEETGID
                     VDIVTGIEESNLGFKGVLEGIQGDDTIIVIDIGGGSTEFIVGDSEGIKFNKSENVGAL
                     RMTERFLKHDIIEDEEFEAMSSFIYDEIDKTLNHIKDRGLKTLIGIGGTITSLSAMNQ
                     ELEIYSMEKIHNSKIHKKEIEEILQKLIKMTLSDKKNLKGLQEKRADIITAGVKILNI
                     IMEKLEIEEITVSEYDNLEGLICQKSKKMY"
     gene            64804..67176
                     /gene="spoIIE"
                     /locus_tag="PC512_000063"
     CDS             64804..67176
                     /gene="spoIIE"
                     /locus_tag="PC512_000063"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein E"
                     /protein_id="HDF2439843.1"
                     /translation="MQRSVAVVKNKTVKPNVIKLISGYIDFTTAAFAVMGFLLSRSII
                     VDSVAPLGIAFFICASKIDKYKIPVFISTLLGILLSSNDFGNVAKYAVCLTIFMAMNK
                     KLKLSDSIAKVAFIGAIILLPISMGQAFFSNRYVYGLLIAGVEAIIMFISIYVFSYGI
                     GLMANVNNRMSVRTEEAISISLLLTFSIMGIGDISLFGISIRTILSTVLILLTSIVGG
                     ATMGASSGVIIGVASILNNMTSAVYMGIYSFSGLISGAFNKINKYFCILGYILSWTII
                     YLYTSGITSNMMQLRDILLGCLIVLVLPERLFNKIEKLIKSNVASNEIVYDYIMRSKN
                     LTNSRLNSIYKTYDDLADTFDKIREKDKVLDQRDIANVIDMIHNDECKSCSMRRMCWE
                     SRFNHTYTMIYNILEKIEEKGELSLNDIPKNFRKECMKPESIVKISNHYYKMFVLDYD
                     WSVKFSESRKLIANQIRSISKSIKSLSQDLEGDIMLDIEKEKNIYEQLERYDITVDKV
                     SYLTKSNSEFEISIEKKTCHDGCMCEDKIVNIISDLVGENMSVRKIGCHCLGGKCKAT
                     FVKSQKYKAVTEVSAMSRDGHILCGDNYTYMEINDGKYMMAISDGMGKGKKAYEESSA
                     TIDILEKMIDAKIKDEIVIDTINNMLLLKSSEEMFSTLDLGILDLKRGCLETIKMGAC
                     STYIKREDGEVDLISSSSLPVGILSDVKIDRKNVKVKEGDYVIMVSDGIVDAGRNNNL
                     GDNWLIYFLKNIETTNPKEISNLILDRALELQALQIEDDMTVLVTKICTK"
     gene            67527..69419
                     /gene="pepF"
                     /locus_tag="PC512_000064"
     CDS             67527..69419
                     /gene="pepF"
                     /locus_tag="PC512_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HDF2439844.1"
                     /translation="MNRKLCKAIIPLFISIFCMLIISIKADQGYQKNNDRAITVMNNN
                     DTEDDAEKKQEIDYEKTCWNLQSLFKSDDQWKKELKSFDKDTKELKNYIGKVTKSPTH
                     LSFALNIKEKLDIRLNKLSAYVKLKQDTNKNSYKYLDMNDSMSKSYGNYMGICSDLEL
                     EILKLSNKDYKKIISNKNINRKYGAYLRDIRRNKVHYLDDKSEDILSKVSSISSLPSQ
                     VYELFRNMDRKTNLTPAQYASELESSDRENRKKAYQDELITYNDNINTIAGLITGQVK
                     KNIFYSQERGYESSLEMYLEADNVDEKVYNNLIRTVNSNMDSLHKYIDLRKKVLKLDK
                     VHSYDMFVPMVKAVDNNINYEKAQSIVYSALSPLGKEYNDVVYKAFNEKWIDVYSHEN
                     KVSGGYCLSVYENHPYILLNYNNSLGSVSTLSHELGHAVYEYLSSKNQNYFNSNPSIF
                     THEVASTTNEALLYEMLIKEAKGNDEKAYYITQYLDLIKDTLYTQTMYAEFEKTIHEL
                     VEKGKSVNALVLNDVWGQLLKKYYGQSYELDQLSKVGWARIPHFYNSFYVYKYATGCS
                     AGVSFAQDILKNGSDNYMSFLKKGSSDYPINLLKSSGINLTNTKPIENTIKKFDSLVA
                     ELEKLL"
     gene            69533..70498
                     /gene="galU"
                     /locus_tag="PC512_000065"
     CDS             69533..70498
                     /gene="galU"
                     /locus_tag="PC512_000065"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HDF2439845.1"
                     /translation="MQVKVKKAVIPAAGLGTRFLPATKAQPKEMLPIVDKPTLQYIIE
                     EAVASGIEEILIITGRNKKSIEDHFDKSVELELDLEKKGKKELLEVVQNISNMINIHY
                     IRQKEPKGLGDAIYCARHFIGDEPFAVMLGDDIVDNDVPCLKQLTDAYEEYRTTILGV
                     QKVNQEDTNKYGIIEAKNIEGRVYKVKDMVEKPESGKAPSNIAILGRYIITPEIFDIL
                     KDLPPGKGGEVQLTDALKILSKKEAMYAYNFEGKRYDVGDKLGFLEATVDFALKKEDL
                     KEDFIKYLKHVCSEFDKNNNVLYNNTDEKIDLIEVNEARELEIQK"
     gene            70998..72602
                     /gene="rho"
                     /locus_tag="PC512_000066"
     CDS             70998..72602
                     /gene="rho"
                     /locus_tag="PC512_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HDF2439846.1"
                     /translation="MRRIFLILDDKVLEGLGSKTLVELREIAKELKIKSITTYKKNEL
                     IEIINSKSKNEEKVNEETKEKNEDIKEDIKNRKENIERESIEKEVEYKSPTKSYNKKE
                     IDTQNISQNQEHRNQRNDYNKTTSVNDSNKSSNISNRMVRNNNKNYYMPKQVDESKIV
                     DEFNTSKEDEVVGVLEILPDGFGFLRGSNYLSTEGDVYVSPSQIRRFNMKTGDKIKGI
                     TRHPKSGEKFRALLYVQKINDENPDTAIQRNAFETLTPIFPEERLTLETNRNEIATRI
                     IDLISPIGKGQRGLIVAPPKAGKTVLLKSVANSIAKNHPNVELIVLLIDERPEEVTDM
                     KESIEGDVIYSTFDQVSSHHVKVAEMVLNRAQRLVEHGKDVVILLDSITRLARAYNLT
                     ISPTGRTLSGGIDPGALHGPKKFFGAARNIRQGGSLTILGTALVETGSRMDDVIFEEF
                     KGTGNMELHLDRKLAEKRIFPAIDIYKSGTRRDDLLLDDEEKTALWRLRREMSNNSVM
                     EITDKVIELIKRTKDNKEFVKSIKNL"
     gene            72755..72955
                     /gene="rpmE"
                     /locus_tag="PC512_000067"
     CDS             72755..72955
                     /gene="rpmE"
                     /locus_tag="PC512_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018591942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L31"
                     /protein_id="HDF2439847.1"
                     /translation="MQKEIQPKYNPVEVRCACGNTFVAGSTKDEIKVEICSECHPFYT
                     GKQKNIEKGGRIDKFKKRFKMD"
     gene            73100..73993
                     /locus_tag="PC512_000068"
     CDS             73100..73993
                     /locus_tag="PC512_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1385 domain-containing protein"
                     /protein_id="HDF2439848.1"
                     /translation="MAKQAVGGQAVIEGVMMQSKDKRAVAVRKSDGEIALKEDRIKSW
                     VRDKNIDKIPFVRGSFVMIDTMIQGIKSLNFSSEFFMEEAEEDKFDLFIKKIFKDKAN
                     DIIIIFSLVIAMLLSAGLFIFIPTLVGGAFSKVMPNDFMLNLIEGIIRIAILFAYIVL
                     ISRSKDIERVFQYHGAEHKSIYCYENDLELTVENARKFKRLHPRCGTNFLFIVMAVSI
                     ILFAFFGWPNPILRIFMRIICVPIVAGLSYEVIRVLGKYDNGFTKIIAYPGMMLQYFT
                     TKEPDDEQLEVALEALKAVVD"
     gene            74011..74859
                     /gene="prmC"
                     /locus_tag="PC512_000069"
     CDS             74011..74859
                     /gene="prmC"
                     /locus_tag="PC512_000069"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HDF2439849.1"
                     /translation="MTIKDIIIKYSDKLKDISDTPRLDTELLLQKTLGVDRLYIHLNL
                     NKELTEEQKTKFMGFAEERLNGRPIAYIVENREFMGLDFFVKEGVLIPRPDTETLVEE
                     IIEICREKKDVSILDIGTGSGAITISLAKYIENSKIMSFDISETALEIAKKNAIINEV
                     GEKIKYINSDLFTAISDSNIKFDIIVSNPPYIKKQDIETLHKQVKDYEPYNALEGGED
                     GLDFYRRITEQGKKYLNKCGILAYEVGHNQAEDVINIMKSNGYKKIYTKKDIQGIDRV
                     VIGYNI"
     gene            74903..75967
                     /gene="prfA"
                     /locus_tag="PC512_000070"
     CDS             74903..75967
                     /gene="prfA"
                     /locus_tag="PC512_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HDF2439850.1"
                     /translation="MLKKLEVLEDTYKDLSEKIGDPDVINDQKVWQKYIKEHADLEPI
                     VMKYREYKSVLDSIKESKEILQEESDEELRELAKMELAEMEEKVAPLEEEIKILLLPK
                     DPNDDKNVIVEIRGGAGGDEAALFAGDLFRMYSRYAERRRWKIELLSASDTGVGGYKE
                     VSFMIKGKGAYSRLKYESGVHRVQRIPSTESGGRIHTSTSTVAVLPEVEDVEVEINPN
                     DLRIDVFRSSGNGGQSVNTTDSAVRVTHIPTGEVVSCQDGKSQLKNKEQALKILKARL
                     YDKALAEQHKDIAAERKSQVGTGDRSERIRTYNFPQGRISDHRINLTLYKLDAFLDGD
                     IDEMIDALITVDQTEKMTAI"
     gene            76096..76776
                     /locus_tag="PC512_000071"
     CDS             76096..76776
                     /locus_tag="PC512_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HDF2439851.1"
                     /translation="MILKVTIIGLLAGVIGTGLGGVISAIFKREVDKYLSFFMGLSGG
                     IMLAVVVFDLMKESMDKMGIINTVIFTFVGALITMYIKTKLDVSGNMASGYLIFISIL
                     LHNLPEGLAIGSSFMSTESLGITLAIVIGLHNIPEGLAMALGLVCNKMKLSKVILFTV
                     IAGLPMGLGSFLGVYFGGVFTSLIGVFLATAGGTMMYVVLEEIFPHSKSVYCIIGFLL
                     GTMIVNYI"
     gene            76805..77845
                     /locus_tag="PC512_000072"
     CDS             76805..77845
                     /locus_tag="PC512_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HDF2439852.1"
                     /translation="MKTIISNIDINNIDYEEIKIQAKLLREGKTVIFPTETVYGLGAN
                     ALDENAVKKIYEAKGRPSDNPLIVHIYEKEEVYDLAKDISDKAKLVIEKLWPGPITII
                     LNKKDIIPYKTSGGLDTVAIRMPSNVIARAIIKEAGIPIAAPSANISGRPSPTKAKHV
                     YEEMNGRVDGIVLGGDSNFGLESTVLDLTEETPMILRPGSITKEVLEELLGEVKLDPS
                     LSKKEDNQKAKAPGMKYKHYSPNADVYIISGKRENVATKINDMIKSNRDKGLKTGVMC
                     ISRNREFYDGEVIDLGNSLEEVASNLFDALIEMDKKGVDVIYSEEFPKTGVGQAIMNR
                     LLKSAGYKVIKA"
     gene            77862..78311
                     /locus_tag="PC512_000073"
     CDS             77862..78311
                     /locus_tag="PC512_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight protein arginine
                     phosphatase"
                     /protein_id="HDF2439853.1"
                     /translation="MNILIVCTGNTCRSPMAEAILRKAIKESGRSIEEYSISSAGIST
                     ANGMGASENSIEVLKEIGIDLSNHRSKVITKKLIDESDIILTMTKSHKEILVQAVPKC
                     KEKVYTFKGFANKNEEDISDPFGGNLDIYRSTMREIMYSVNEIVKKI"
     gene            78328..78780
                     /gene="rpiB"
                     /locus_tag="PC512_000074"
     CDS             78328..78780
                     /gene="rpiB"
                     /locus_tag="PC512_000074"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 5-phosphate isomerase B"
                     /protein_id="HDF2439854.1"
                     /translation="MKIGLGCDHGGYNLKKEIISYLESKGIECVDYGTNNATDSVDYP
                     VYGEIVANSVINKEVDYGILCCGTGIGISLAANKVPGIRCAVVSDVFSAKMSKAHNDA
                     NMLSLGERVLGKGLALEIVEAWINTDFEGDRHARRVNMIKSIEEKHNK"
     gene            78816..79445
                     /gene="upp"
                     /locus_tag="PC512_000075"
     CDS             78816..79445
                     /gene="upp"
                     /locus_tag="PC512_000075"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HDF2439855.1"
                     /translation="MSKVVETNHPLIQHKLTLMRDKNTGSKDFRELLTEIAMLMGYEI
                     TKDIPLKDVEIETPIQKTSSKVVAGKKLAIIPILRAGLGMVDGLVSLMPAAKVGHVGL
                     YRDPETLKPVEYYCKLPQDIGERDIIVVDPMLATGGSAVAAIDLLKSKGAKSIKLANL
                     VAAPEGIAEVQKYHDDVDIYVASVDERLNEHGYIIPGLGDAGDRLFGTK"
     gene            79746..80561
                     /locus_tag="PC512_000076"
     CDS             79746..80561
                     /locus_tag="PC512_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF2563 family selenium-dependent molybdenum
                     hydroxylase system protein"
                     /protein_id="HDF2439856.1"
                     /translation="MKNCIVVRGAGDLATAVIHKLHNSGFKVVALEIEEPLAIRRQIS
                     FCEAVYEKKVTVEGVECIFCNTEKEIEEVLSQHKVALIIDPKGEKLSKLNPIVLVDGI
                     LAKKNLGTTKDMAPLTIALGPGFCAGEDVDVVIETMRGHNLGRIITNGRAEKNTGVPG
                     AIKGFSKERVMHSQYDGIMENVCKIGDIVEKGDLLCYINNYEKKHEVRATISGVLRGL
                     LKDGAKVNKNLKILDIDPRKEEVKNAFTISDKARCIAGGVLEAILNNGIYPQN"
     gene            80787..81224
                     /locus_tag="PC512_000077"
     CDS             80787..81224
                     /locus_tag="PC512_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dCMP deaminase"
                     /protein_id="HDF2439857.1"
                     /translation="MRPSWDEYFMEIAEVVKKRSTCIRRQVGAVIVRDKQILTTGYNG
                     SPRNLEHCENIGCKRQELNIPSGERHELCRALHAEQNAIIQAAHNGISVDGATLYVTT
                     RPCVLCAKMCINAGILKIVYEGDYPDDMSTELLKEAGIELIKF"
     gene            81409..81636
                     /locus_tag="PC512_000078"
     CDS             81409..81636
                     /locus_tag="PC512_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AtpZ/AtpI family protein"
                     /protein_id="HDF2439858.1"
                     /translation="MSKRNTHTEIAKLFSLISQIGLMIVISILGCTFLGKFLDSKLNT
                     TPVLTIIFLLLGVGGAFSGVYKTLIVYTRRK"
     gene            81641..82027
                     /locus_tag="PC512_000079"
     CDS             81641..82027
                     /locus_tag="PC512_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase subunit I"
                     /protein_id="HDF2439859.1"
                     /translation="MDIKLLNQVRSVTKGIVIFDVVLIVLMLITSTLSKPVLLGLIFG
                     SIIAMLNFRLLAISLEKSVTFPAGKAQAYASAQYAVRLFIMAVVLIASATVPHLNIIG
                     TALGLLSTKFVILSKNFINKLKRKEA"
     gene            82030..82734
                     /gene="atpB"
                     /locus_tag="PC512_000080"
     CDS             82030..82734
                     /gene="atpB"
                     /locus_tag="PC512_000080"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HDF2439860.1"
                     /translation="MNQAHYYLIGNFKISETILVSWGIMAFLAIASYFLTRNLKKVPT
                     SKVQIFLEFAVGGLAKMVTDVMGKNTVKRMPYMIPYIGSLFLFFACSNLSPLLGLRSP
                     TTDLDTTAAWAMITFFMIYFAGVKFKGLSYFKELAQPLAIMLPINIIGELARPISLSF
                     RPFGNILGGTIIMGLFYQLLGFISSLIPGLSIPIGEILIPVPLHLYFDLFAGLLQAYI
                     FIMLTMVFISSAGELD"
     gene            82803..83063
                     /gene="atpE"
                     /locus_tag="PC512_000081"
     CDS             82803..83063
                     /gene="atpE"
                     /locus_tag="PC512_000081"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HDF2439861.1"
                     /translation="METAIVAAASAIGAGIAVATGIGAGIGQGIAAAKAAEAVGNQPE
                     AKGDITSTLLLGVAIAESSAIYGLVISIILLFVNPFFKYLGM"
     gene            83186..83683
                     /gene="atpF"
                     /locus_tag="PC512_000082"
     CDS             83186..83683
                     /gene="atpF"
                     /locus_tag="PC512_000082"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HDF2439862.1"
                     /translation="MEKALVGITWEFVFQIVNTFIIFLLLRKLLFKPVLNIIESREND
                     IKSDLVEGEKAKNEGLALKKEYESKINFAKDEGQEIIKQATIRAEQKSDDIVNTAKKD
                     ALDIKEKANKDIEQERQKVINEIKNDISNIALLAASKVIEKDLDKSKHEELIENFIKE
                     VGEAK"
     gene            83680..84225
                     /locus_tag="PC512_000083"
     CDS             83680..84225
                     /locus_tag="PC512_000083"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HDF2439863.1"
                     /translation="MINVIANRYAEALFQLGEEENSTDVLFKELEKVVDMMTKVSKDF
                     YKVLKSPLVSKSEKKNLVEIIFSKEVSSNIKNFLKVLVDKDRISYLEDIELAYKELLN
                     KKNNVIDGVAISAIPMSETDIKELEVKLSNKYNKNVTIENVVDKTILGGVLVRIGNEQ
                     IDGTVKTRLDKMKEKLSEVIS"
     gene            84242..85744
                     /locus_tag="PC512_000084"
     CDS             84242..85744
                     /locus_tag="PC512_000084"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003405060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HDF2439864.1"
                     /translation="MNLKPEEISSIIKQQIKNYENKVELTDTGSVLTVGDGIASVYGL
                     EKAMSGELLEFPGEIYGMALNLEEEVVGAVILGDDSEIKEGDIVKRTGRIVEVPVGEA
                     LIGRVVNSLGQPIDGKGPIAYTKTRPVESEAPGIIDRRSVYEPLQTGIKSIDSMIPIG
                     RGQRELIIGDRQTGKTSIVIDTILNQKGKDVICIYVAIGQKRSTIAQLVSSLEKGGAL
                     DYTIVVSATASESAPLQYIAPYAGAAMGEEFMYNGKHVLIVYDDLSKQAVAYREMSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDELGGGSMTALPIIETQAGDVSAYIPTNV
                     ISITDGQIYLQPELFYSGVRPAVDPGISVSRVGGSAQIKAMKKVAGTLKLAYSQYREL
                     AAFSQFGSDLDEDTKKRLAQGERIVEILKQGEHQPIKVENQVMIIYAVINNHLEDIPI
                     DNIARFESELYAFVDNNYPEISRKILGGEDFTHDLTDAINEFKEKFVVEV"
     gene            85772..86650
                     /gene="atpG"
                     /locus_tag="PC512_000085"
     CDS             85772..86650
                     /gene="atpG"
                     /locus_tag="PC512_000085"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F1 subunit gamma"
                     /protein_id="HDF2439865.1"
                     /translation="MAGAGIKAIKTRMGTVESTKQITKAMELVASSKLRKAKEKAEDS
                     REYFNTLYNTVKDIAQTTRGIRNEFLKEREVKNKCYVVVAGDRGLAGGYNSNVLKESV
                     SHMKGKKETVITVGKKAHEFFSKRNYNIAKDINSVEACGYEDATEISQTIIDLYKKGE
                     VDEVYIAYTKFKSALSQEVEILKLLPLVFEKDTDEQGMAVKEEKQNRSKVQYIPSAEA
                     VLSYIVPQFISGTVYGGILESFASEQGARRTAMESATDNANEMLSNLELSYNRARQSA
                     VTQEITEIVGGVEALK"
     gene            86663..88057
                     /gene="atpD"
                     /locus_tag="PC512_000086"
     CDS             86663..88057
                     /gene="atpD"
                     /locus_tag="PC512_000086"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HDF2439866.1"
                     /translation="MANVGKVVQIVGAVLDVKFDSEQSLPNLLNALVIKLGDKEIVAE
                     VAQHIGDDTVRCIAMSATDGLVRGMEVVDTGGPISVPVGDETLGRIFNVLGKPVDGKP
                     APKSAPKLPIHRPAPAYDELETTAEILETGIKVVDLLAPYLKGGKIGLFGGAGVGKTV
                     LIQELINNIAKQHGGISVFSGVGERTREGNDLYGEMSESGVINKTALVFGQMNEPPGA
                     RMRVALTGLTMAEHFRDEQGQDVLLFVDNIFRFTQAGSEVSALLGRMPSAVGYQPTLA
                     TEMGALQERITSTKKGSITSVQAVYVPADDLTDPAPATTFSHLDAKTVLSRQISSLGI
                     YPAVDPLESTSRILDPSIVGKEHYEVARGVQSILQRYKELQDIIAILGMDELSDEDKL
                     IVARARKIQRFLSQSFTVAEQFTGNPGQYVPVKETVRGFKEILEGKHDDLPESAFLFV
                     GTIEDAVRKAKGSM"
     gene            88060..88320
                     /gene="atpC"
                     /locus_tag="PC512_000087"
     CDS             88060..88320
                     /gene="atpC"
                     /locus_tag="PC512_000087"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F1 subunit epsilon"
                     /protein_id="HDF2439867.1"
                     /translation="MASEFSLKVVTPSNTFYDGDVEMIVVRTTKGDKGVLKGHIPFVS
                     GIPVGTLKIKKEGSFKEAKIAEGFINVTQDKTVILTESAEWI"
     gene            88782..89162
                     /locus_tag="PC512_000088"
     CDS             88782..89162
                     /locus_tag="PC512_000088"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HDF2439868.1"
                     /translation="MNIFDIGVDIIEIDRIRKAVDKNNRFLEKIFTDREIEYFNSKNF
                     KAESIAGNFAAKEAISKSIGTGIRVFNFKDIEVLRDEMGKPIVKTYNNLAKMCIDYNV
                     LEIKVSISHSKDYAIANAITIIKD"
     gene            89177..89638
                     /locus_tag="PC512_000089"
     CDS             89177..89638
                     /locus_tag="PC512_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HDF2439869.1"
                     /translation="MMDKTAKEIMTTDVIVAKQDDSIADVANMLIAEKIGGLPVVDSE
                     NRVVGIISETDILKKEKYIEAPLYINLLQGLIFLDDLKKVEKDIKQVAAYKVGELMSK
                     DIIKVHEDDKFDDVANVMIKKSINRVPVVDDDNKLKGIICRYDIIKALYNE"
     gene            89659..90249
                     /locus_tag="PC512_000090"
     CDS             89659..90249
                     /locus_tag="PC512_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2439870.1"
                     /translation="MRKKWTIVCIMFLALVIIVIGCQKRQSTKEEVYKDFQKQISDMN
                     YYSCKAEVEVVGNKSPHNYVLIHTYKKTDNYKLEVISPKHLKGKSIEYQGDKILVKNP
                     KISDVVELPNTGKNNQYLFVGDFIKNYLQNEEMKVKLSKGHLVLETFIPGDNKYFNKQ
                     VLYVNADTKNPEKMEVLDKEGVPRFTVKYKDFEYRN"
     gene            90264..91421
                     /gene="alr"
                     /locus_tag="PC512_000091"
     CDS             90264..91421
                     /gene="alr"
                     /locus_tag="PC512_000091"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HDF2439871.1"
                     /translation="MQKITVPTWAEINLDNLRFNLNNIKNLLEEDIKICGVIKADAYG
                     HGAVEVAKLLEKEKVDYLAVARTAEGIELRQNGITLPILNLGYTPDEAFEDSIKNKIT
                     MTVYSLETAQKINEIAKSLGEKACVHVKIDSGMTRIGFQPNEESVQEIIELNKLEYID
                     LEGMFTHFATADEVSKEYTYKQANNYKFMSDKLDEAGVKIAIKHVSNSAAIMDCPDLR
                     LNMVRAGIILYGHYPSDDVFKDRLELRPAMKLKSKIGHIKQVEPGVGISYGLKYTTTG
                     KETIATVPIGYADGFTRIQKNPKVLIKGEVFDVVGRICMDQIMVRIDKDIDIKVGDEV
                     ILFGEGEVTAERIAKDLGTINYEVLCMISRRVDRVYMENNELVQINSYLLK"
     gene            91454..91741
                     /locus_tag="PC512_000092"
     CDS             91454..91741
                     /locus_tag="PC512_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix protein, CopG family"
                     /protein_id="HDF2439872.1"
                     /translation="MYDKSKEKIEVTLPDSLISEVDSIVQMENSNREDFAKAAFQFYI
                     TQKKKIHIKESMKTGYREMGQINLSLAELGMTVEEVSSDDKNEGKIAQGEY"
     gene            91710..92093
                     /locus_tag="PC512_000093"
     CDS             91710..92093
                     /locus_tag="PC512_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HDF2439873.1"
                     /translation="MKGRLPKVSTNCEIKRGDLYYADLSPVVGSEQGGVRPVLIIQND
                     VGNKYSPTVIVSAITSQINKAKLPTHVEISSNEYGLNKDSVILLEQIRTIDKKRLREK
                     IGCLDENMMIKVDDGLQISLGLFTF"
     gene            92264..93091
                     /locus_tag="PC512_000094"
     CDS             92264..93091
                     /locus_tag="PC512_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HDF2439874.1"
                     /translation="MRDHKGLNEIARIIRRDIVSMIHRAKSGHPGGSLSVVEILTALY
                     FDEMNVDSSNPKMEDRDRFVLSKGHAAPALYATLAEKGYFDKEELNGLRKIGRMLQGH
                     PDMKGTPGVEISTGSLGQGFSVACGMAMASKLDNAPWNVYTLLGDGEVQEGIVWEAAM
                     SAAHYKLDNLIAFLDNNGLQIDGDIESVMSLGSIVDKFKAFGWNVIEIDGHDFDQIFA
                     ALDIAKSTVKKPTMIVAKTIKGKGISFMENQAGWHGTAPSDEELEKALLELGGADNE"
     gene            93084..94025
                     /locus_tag="PC512_000095"
     CDS             93084..94025
                     /locus_tag="PC512_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HDF2439875.1"
                     /translation="MSKMATREAYGKALVKLGQINDNVVVLDADLSKSTKTHDFYKSF
                     PDRFFNMGIAEQNLIGAACGLSTAGKIPFASTFAMFATGRAFEIIRNSVCYPKLNVKI
                     CATHAGLTVGEDGASHESVEDIAIMRAIPNMTVLVPADGVETEKIIFEIAKYNGPVYV
                     RLGRSSVPVLFDEDYKFEIGKGTVLREGKDVSIIACGIMVNEALLAQEKLQEEGISAR
                     VINMSSIKPIDKDLILESAKETNAIVTVEEHSIIGGLGSAVSEVVGESCPTIVKKVGI
                     KDTFGESGTPNELLKKYELTCDDIIKTVKEAIIAKRM"
     gene            94448..95542
                     /locus_tag="PC512_000096"
     CDS             94448..95542
                     /locus_tag="PC512_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2439876.1"
                     /translation="MSEKVNVKTVISFAGAYVATVIGSGFATGQEIMQFFSFYGFAGI
                     IGGIISMVLFSWMGASVMSKGKELQLKEPIKIYRVYCGKYLGIFFEWFGPLFLFGVFV
                     VMISGAGATLTEYYGLNPFVGRVGMAVVALLTVSLGLDKLSKILGGIGPIIIIFTLLV
                     GGISLAKNIGNIGEAAQVLSTVKIAKPVPNAYLSGVIYTTYNTIVVMAFLTGLGASAA
                     NKKEAICGGILGGVALMAAAIMMHLAILSDIGNLYSKAIPSLFLADKISPVIGVLFSI
                     ILILGIYTTAVPLLWSVTNRFVDDKHPKFKLITLIAAILGLIGGFLPFDKLVGILYPY
                     TGYMGVIILVCVLYRQITKTSGYQEGISDK"
     gene            95768..96184
                     /locus_tag="PC512_000097"
     CDS             95768..96184
                     /locus_tag="PC512_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2439877.1"
                     /translation="MNVKFNIKGIIYGVIALVFVIGGFIFIPSMFVEKSKPIDYTVLQ
                     RNSIPEKILDVMDKYTNEERALAAKIDNKIYIIVTRGNNKYGIEMDKIESVVEEGKDV
                     LRVKIKYKDKEDSFPYIVVETNMSELPDRIELNATK"
     gene            complement(96366..96935)
                     /locus_tag="PC512_000098"
     CDS             complement(96366..96935)
                     /locus_tag="PC512_000098"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HDF2439878.1"
                     /translation="MKKEFRKKVIESRKNKNANFVLSNSNLITEKLLQMEDIRNATNI
                     MLYLNFNNEVQTDNLIKKLLSLKKIVSSPITIKENHTLIPTQITDLKEGLRIGAYGIR
                     EPNEKSPTIDIKALDVVIVPAVAYDIHCYRLGYGGGFYDRFLENLRKDAITIGIAFDF
                     QIFDSIPKETHDAQLDYIVTETRIITPNS"
     gene            97089..98246
                     /locus_tag="PC512_000099"
     CDS             97089..98246
                     /locus_tag="PC512_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S41 family peptidase"
                     /protein_id="HDF2439879.1"
                     /translation="MYLVISKKKAIFLGVILVIITAMVTSAFQLTLGNKVVISKELYE
                     DYKKYDKLLGLESIIKQDFYKKVSDTDLVNGAAKGLFLGTNDKYSGYYTKDEMENLIN
                     DSEGSYVGVGMYIGASKDGGLVVVPMKDSPAEKAGVKSGDKLVKVNGKSVSYKNSDEA
                     VRMMKGKKGKTVELTILREDKQLNFKVKTDQIIEKSIESKVIDNDLGYIEITQFISST
                     YTDFDKALKELKAKNIKGLVIDLRNNPGGMLDICKEVADELIGEGTIVYTKDNKGNTE
                     YLKSDKEKLGLPIVVLTNGESASAAEILTAAIVDNKEGISVGTTTFGKGLVQSVVRLK
                     DGTGYKLTTAQYFTPNGDYINEKGIKPTIEEKDENKQLDVATKWLREQIDK"
     gene            98850..99332
                     /locus_tag="PC512_000100"
     CDS             98850..99332
                     /locus_tag="PC512_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDF2439880.1"
                     /translation="MYNNIKNILKENHITFEEYDHEPILSFEKAKEIREKLQYTGVES
                     KSLFIKDRSGNYYIFVTTEGKKLDPKTIKNVLGGKVSICSKEELTQKTQCLPGCVSPF
                     GYEKNISLVIDQDIFNHDKIIFSPGIPEKTFIITASGFKKVINNINNTTYKYIYINEF
                     "
     gene            complement(100031..101185)
                     /gene="nagA"
                     /locus_tag="PC512_000101"
     CDS             complement(100031..101185)
                     /gene="nagA"
                     /locus_tag="PC512_000101"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HDF2439881.1"
                     /translation="MKSFIYADKFFMKHGIKEKGYLSIINGKFGEFQQERPNVTDNVI
                     DFSGKYIAPGLVDTHIHGLLGADVMDNTFEAINTISKGLLKYGVTSFLPTTLTDSVDT
                     LSDSVENISNSFNRVEGAKIQGIYLEGPFFTEKYKGAQNEKYFKDPDINILKLWQKKS
                     KNLIRKIAIAPERKGSIELTRYATKNNISVSLGHSSATFEQVKQVVNSGAKVFVHTYN
                     GMSPLNHREPGMVGAAMVLKDTYAELICDGHHVSPIAVKIMMDAKSSNNIALITDCMR
                     AGAMEDGKYTLGKFNVNVKNSVARLNSGSLAGSVLTMDKAVRNIVDWNIATLEDAIKM
                     ATYIPALSCNIDNVCGSIHQGMEADFIVTDKDFNIYETYISGICKYKVNK"
     gene            complement(101268..101993)
                     /locus_tag="PC512_000102"
     CDS             complement(101268..101993)
                     /locus_tag="PC512_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2439882.1"
                     /translation="MIKRNDKRPIYDQLVEILRTKIENEMEPNDRMLSERKICDEYGV
                     SRTTVRLAMAELEHMGYIYKRHGKGTFVAALSQNSQNLMESYSFTDYMRTQGKKPGTK
                     VLSFEVVESTKYFSEKLGITPGEKMIKIMRLRLADDLPMMLERTYLPMKEFIGLTKEK
                     IEQKPLYEIFREDYGEIIKVADEEFSAGIISDKEAKLLEVPGDSPCLKLLRTTYNDDN
                     IVIEFTLSVARSDKFVYRVRHVR"
     gene            102260..103189
                     /gene="pfkB"
                     /locus_tag="PC512_000103"
     CDS             102260..103189
                     /gene="pfkB"
                     /locus_tag="PC512_000103"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HDF2439883.1"
                     /translation="MITVITFNPSIDRMYRVNNINIGEVQRVVSKNATAGGKGLNVSK
                     VCKILKENPLAMGFLGGFNGEFIKNELRKLDIQNKFTKIEQETRNCLNIIEDNKVSTE
                     FLEKGPIVEKSDLERFENDIEEVLKNTKILVASGSYCENMPIDYYEKIGNICRANNIK
                     FILDTSGEALKIALKSKPYLIKPNIDEIRHLLGINIESREEIILSGKKLIEMGAENVC
                     ISLGKDGMVYLNEDNVYYVKVPVVKCINTVGSGDSTVAGFSVGILRGYKIENLLKFAN
                     ACGISNALNMETGFVDLGEIDKYQDLVEVKKLS"
     gene            complement(103318..104235)
                     /locus_tag="PC512_000104"
     CDS             complement(103318..104235)
                     /locus_tag="PC512_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDF2439884.1"
                     /translation="MKNIKMGMIGLGSIAQKAYLPILTKSERFEFVGAFTPNKVKREK
                     VCSDYRIMQFDSIESLAKKCDCIFLHSSTETHYEIIKILLNLGVHVYVDKPLASTVSQ
                     GEELIELSTKKNLNLMVGFNRRFCPMYKEIKNNATEIVSINICKHGLNSLRNVKFDST
                     LIDDYIHVIDTALWLANEDVEISGEDLFLTDNKNLIFVSHKLKGKNFSINTSMHRDSG
                     TKLEQVEILSKGKIQRVKNLNVLEIEEGGNLTLKQSGAWVNILKQKGFEDISNHFIDC
                     IENNIKPAISGEECIKAQRLLEKIINSVK"
     gene            104705..105874
                     /locus_tag="PC512_000105"
     CDS             104705..105874
                     /locus_tag="PC512_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDF2439885.1"
                     /translation="MKMFKLEEQKLKDLGAIITTNEIKQQPELWLETYEIYKSNKEKL
                     SRFIDTISNNHGQFRVIFTGAGTSAYIGNSILPYLKNKNDIRKYIFEAIPTTDIVSNP
                     YDYLKKDIPTLLISFARSGNSPESLAALNLGNKIVDNFYHLAITCNPEGELAKMTKND
                     ENNYLLLMPSKSNDEGFAMTGSFSCMMLSAMLIFDSLEDDVEKSYINAIVEMGRNVID
                     RKDEIHELINKDFDRVVYLGSGGLGGLTQEAQLKLLELTAGKISTVYDSPMGFRHGPK
                     SFIDENTLVFEFVSNCLYTRKYDLDVLEEIKRDKIAKFTCAVSVENENNFSGTKFEFK
                     EKYNKLPDVYLAMPYILFAQTIALFVSVKVGNKPDTPSATGTVNRVVKGVTIYEY"
     gene            105923..106774
                     /gene="gatY"
                     /locus_tag="PC512_000106"
     CDS             105923..106774
                     /gene="gatY"
                     /locus_tag="PC512_000106"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatY"
                     /protein_id="HDF2439886.1"
                     /translation="MALVTTTSMLKKAQDEGYAVGAFNVENMEMVIAVIEAAEELNSP
                     VILQTTPSTVKYAGLDYYLANAKVAAERVKIPVAMHLDHGSSFDLAMKALRSGYTSIM
                     IDGSHESFENNISISKSVVKACSPSLIPVEAELGKVGGKEDDLDGGNSNDYTNPKEAK
                     EFVDRTGISSLAIAIGTAHGLYKGEPKIDLDRLSEIKNVVSIPLVLHGGSGIHDDIIK
                     EAIKRGIAKVNYATELRIAYSKGVKKVLDEDSEVIDPKKYGLAGLQSVKDFVKEKIKV
                     CGSVNRV"
     gene            107100..109001
                     /locus_tag="PC512_000107"
     CDS             107100..109001
                     /locus_tag="PC512_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF2439887.1"
                     /translation="MRERIILETLKNSSGYLNIDYFADKLGVSTRTIRNEIKKIETIK
                     ECNGFKLEYKSKLGYILNIKDQDKFEHYLRNLPSDLVENPEQRLESIIVELLVNEGYK
                     TIEQLSKKFLVSSSQIKNDLKKIDEKIKDTELKLERKAHYGIKIEGSIKEIQSILVDS
                     YFRGNRNITEYRNKFIDNLKLANIRSTIKNVLNEHDLEANLTELEEILAQIIILYIRV
                     SMRVAGNASDLKLYTEDLIIDKLLDKIFRDKKYNLNYDEKYYLKELIKLKTKDKKATI
                     KNIDKNKLQDIMFEFFREIDKKYNSNFLEDKEFFNLFYLHIACLIERIKKNHKIINPF
                     SVKISQQYPTVFNLSIQFSKIIENEYHIKISQDEIGFIATHIAVPFEKREEANFNKKY
                     KIAIICSSGGGSAFLINLRLKEIFPNAEIRNFSLLEEKAVIEFAPDLIFSITNLLFEI
                     NAPVILINEILDELDYLDIKESVRFADHIGNISSPKQYILGLFDKNHFRCIKDKAKYK
                     DILDSMSKCIVDEGACSPTYPKDVWERESYLSTIYTNGVAIPHPIEMTGNKNIISVAL
                     IQTDIIYENRVPKIIFMISLIKGNLELHKQISKYLSKIMANKDMVDMLNKSQSYEEFM
                     YKLKIYLGG"
     gene            109004..110047
                     /gene="ypdE"
                     /locus_tag="PC512_000108"
     CDS             109004..110047
                     /gene="ypdE"
                     /locus_tag="PC512_000108"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HDF2439888.1"
                     /translation="MNIEFFKRLSEADGIASNEEEVRHVLLEELKAYSDKIICDGLGS
                     IIFSKIKDESAPNVMICAHMDEVGFMVRSIDKLGMIHLITIGGVKPLAQFVQKVRITT
                     KEGKKIPAVINATYNNGKAENIYADIGAYTEEDVYNLGINVGDMVTYTTSFEEFTLPD
                     RLVGKAFDDRIGCFVMGEVLKELRKENLNCNIHFAATSSEEVGIRGAKTSTQLINPDI
                     VFVIDVACAKNEFVRDYTNQKQIDKGVMLMHRDRTLVPSRKMIDYVMEIADKNNIPLQ
                     HDMFESGGTDGGEAHLVNEGKPCVVTCVPVRYGHCAFSIVSNKDLENIIRLYTQLILN
                     FDEEQYKHIRNFI"
     gene            110062..110367
                     /locus_tag="PC512_000109"
     CDS             110062..110367
                     /locus_tag="PC512_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDF2439889.1"
                     /translation="MSTEVQIMELISTAGESKSKAFEALKKVKSKDFKGAKLLIEEAR
                     KIDIEAHRIQTELITQDLNEDVESPAMSLLMVHAQDHYMTSQLAKDLIEALIYCLDK"
     gene            110464..110799
                     /locus_tag="PC512_000110"
     CDS             110464..110799
                     /locus_tag="PC512_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2439890.1"
                     /translation="MKILLCCAGGFSTNMLMQNMKKVVKESAKLNEKDFEFTAIPADS
                     IESEVDDWDIVLIGPQIAHKIDFLKGILEPKNKPFAVIDKDVYGKMDGATVMKLALIT
                     YKKHQLAQG"
     gene            110831..112153
                     /locus_tag="PC512_000111"
     CDS             110831..112153
                     /locus_tag="PC512_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2439891.1"
                     /translation="MFSKFEAFMNRVFMPLAHKVDNQRHLGSIKAGMVAMTPFTILGS
                     IFAILPALPNMLGENNPISKFILNNSAILDLPVSLSIGLIGLYACMCIAFNLGNYYKL
                     YIPGCVALSTFSFLFLVASFTPDGALEIGNLGAKGLFTGMIAGLGSVELYNFCNKKNI
                     TIKMPENVPDFVSRSFELIPTTIIVCGTFIVARFISLKVFGELPPQILTQFLSPLVGS
                     MDNPWSVLALNFAICTIFFFGIHSSVFSPITRPIMITFIAENIAAMQAGETIPHFFTA
                     GASSAFFGFTGCGISIGCVIACMLSKNASYKKIGRVSLFPALFGINEPILFGAPIILN
                     PIMFIPHVFGGAIIGTLPMFFMHWGWLAKPVFDPPYVGVFLEGFLTNGDWHSILANAL
                     QLVLAVLLYWPFFKIMERQQNNKKQKEETKNIFSKEEEDLLDDLGLDF"
     gene            112163..113233
                     /locus_tag="PC512_000112"
     CDS             112163..113233
                     /locus_tag="PC512_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDF2439892.1"
                     /translation="MNNTMERLVSLIYKRGVDALLIKAKNTKRYIGALSGSGVYVLVT
                     KDKNYQILDGRYIDEADKKTTGFIKRIVSQGSYIPTIIELLKELNIKKLAIENQAMSI
                     QEYLSLKNEGFEINLITNELWKLRAIKSKEEIELIKKACEITDEVFDEVISEIKKDMT
                     ELEVSALIQYHALKKGASGMSFETIVVSGERGAMPHGRPTNKKLKVNEAITIDFGVVY
                     QGYQSDMTRTISIGKPPKIIKEIYDVVLEAQLSAIESIKEGTRASDVDKVARKIIDKH
                     GFGEYFNHGLGHGIGLGDGEVPTLNPNSEDILVEGMVMSCEPGIYIPNVGGVRIEDDI
                     VIIDGKGVPLNKTSKEFIILGE"
     gene            113238..114425
                     /locus_tag="PC512_000113"
     CDS             113238..114425
                     /locus_tag="PC512_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDF2439893.1"
                     /translation="MKYNFNKVLNRKEGNCRKWSNHVIKEKFGLNEDAIPMDLADIDF
                     ECAPAIKESILKRASVGDYSYTFIGDDFYDAIINWNKRRFDVYIEKDWIKLTFGTVST
                     LHYIVQAYTKEGEGVLINTPAYDPFAEAVVNNNRKLCCSSLKLDNNRYYLDLEDMENQ
                     MKYENIRLLIFCSPQNPSGRIWTKEELYQVSELCLKYNVILVSDEIHRDIIFKDYRFV
                     SLWNAHPEIYKNSIICVSPNKGFNLGGLKTSYVLIRDVKIRETLLERLKSNSITSPNV
                     FAIPAIVAAYNESEEWLDAMTSYVEENFEIVYDFFETNIPKAKVMKSDSSFLAWIDVR
                     EVFRNEEESKEFFRHANLTMVVGSYFVKDGDGFIRINVGCPRETLNEALNRIKKTYIS
                     MYC"
     gene            complement(114622..115494)
                     /locus_tag="PC512_000114"
     CDS             complement(114622..115494)
                     /locus_tag="PC512_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HDF2439894.1"
                     /translation="MNILQNENLIIESSSFGAELTKIFSKKYDKNILWDGNKKYWGRQ
                     SPILFPIVGKLFDNETIIEENLYSMTQHGFARDMDFEIVDKGDTFVTYKLTDNESTLK
                     KYPYSFELIINYTLNDNSIEVEWIVKNTDSKDIFFSIGGHPAFNLPFYEQNDFSKHYL
                     EFKSKNDVEKINLNGSFTDDIIPIGKLKNLQLNPEVFKNDALIYTNIDEVSICNNDGS
                     KYVTISMEDFPLVGIWTPYYSETNSTAPFLCIEPWYGLADSINSNKIYKDKKFINKLS
                     KGKVFTASYNINIH"
     gene            complement(115888..116079)
                     /locus_tag="PC512_000115"
     CDS             complement(115888..116079)
                     /locus_tag="PC512_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2439895.1"
                     /translation="MDDFSKLKSLYEDGYRCIYHDCVDNNYTIYLKNFYTEGSETIEL
                     SSESDFSQFKDYIDGLRMS"
     gene            116299..117345
                     /gene="cobT"
                     /locus_tag="PC512_000116"
     CDS             116299..117345
                     /gene="cobT"
                     /locus_tag="PC512_000116"
                     /EC_number="2.4.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide--dimethylbenzimidazole
                     phosphoribosyltransferase"
                     /protein_id="HDF2439896.1"
                     /translation="MSLLESISKNIYSLDNSSIEKTKQRLDRLIHPTGSLGKIEDICM
                     QLAGIFGNENFDTSKKVIIAFAGDHGVYEEGVAPDPQNITKLQFPNFSKGLCGVGVIS
                     KFVGADVVAVDVGINCDEKLDGVLDYKIRKGTSNMAKGPAMSKQEAIRCLEIGIEIAE
                     QCIEKDYKVIGIGEMGIANTTPSTAIISVISGCDPLEVTGIGAGLKKERLKHKAEVIR
                     KAIEINNPNPTDGVDILSKVGGFEIGSMAGVILGCSANRIPVVIDGFISYAAALIAYK
                     INPKTREYMIASHLSAESGTKRALDILKLDPLLNMDMRLGEGSGAALAFDIIEASNYT
                     YKNMATFDEIDMGR"
     gene            117377..117937
                     /gene="cobU"
                     /locus_tag="PC512_000117"
     CDS             117377..117937
                     /gene="cobU"
                     /locus_tag="PC512_000117"
                     /EC_number="2.7.1.156"
                     /EC_number="2.7.7.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional adenosylcobinamide
                     kinase/adenosylcobinamide-phosphate guanylyltransferase"
                     /protein_id="HDF2439897.1"
                     /translation="MSKIILVTGGARSGKSNFAEKLCFDRNNNTAYIATSIPFDDEMK
                     DRVKKHQENRPRNWNTYEIYEDIYSIIKEIYKEHETVILDCVTLLVNNLMFEHNLNIE
                     ESSQEEINKLEQYIKEQVVKLIEEIEKTNLYFVFVTNELGMGIVPGNKLSRIYADIVG
                     RINQYIASKSNEVYFVVSGIAMKIKE"
     gene            117947..118720
                     /gene="cobS"
                     /locus_tag="PC512_000118"
     CDS             117947..118720
                     /gene="cobS"
                     /locus_tag="PC512_000118"
                     /EC_number="2.7.8.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobinamide-GDP ribazoletransferase"
                     /protein_id="HDF2439898.1"
                     /translation="MKRFILILQFLTRIPIKLNVGFDDEFYKSIVYFPLVGFVIGILS
                     YLIGWISMLLFEPFIASIIITLAGVLITGGLHIDGLGDTFDAIYSYRDKEKMLEIMKD
                     SRLGTNSLLAIMFVLLLKVGFVYDIISNNSLWVIIFMPMIARLGVMLLTYKTVTPREK
                     GMGNLFIGKLTTSMLITAIIYTLLIVALITKFIFLLPNIVLIKVLGSIIVVFVFIILF
                     KKHIYKKIDGVTGDILGCGIELSELVYLIYIYLLIFMFF"
     gene            118740..119354
                     /locus_tag="PC512_000119"
     CDS             118740..119354
                     /locus_tag="PC512_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HDF2439899.1"
                     /translation="MIRLILIRHALTNDNKKGRLSGHINSCISEEGKLQINKITRYLS
                     NENIDKVYTTPSTRTKDTVEKISKLKLLEIEEKEALREISFGDFEGRTFEEIKIKYPN
                     EFEKMIKEGNNYRYPNGESLIDSYKRVAKEIDNIILENDSNLDTKTILICSHAGTIRN
                     IITHLISGSYKYHWNFKIDNASITVLEIDGGFAVIDKMNFTDFI"
     regulatory      119421..119600
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            119730..121229
                     /locus_tag="PC512_000120"
     CDS             119730..121229
                     /locus_tag="PC512_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobyric acid synthase"
                     /protein_id="HDF2439900.1"
                     /translation="MLQGTASNVGKSVLVAGLCRIFKQDGYTVAPFKSQNMALNSFIT
                     KEGLEMGRAQVFQAEAAKIEPIADMNPVLLKPSGNNKSQVIVRGKVVGEMPSSKYHDY
                     KLELVDVLKETFNSLNSRYDIVVMEGAGSNAEINLKDRDISNMGMAEIADAPVIIVGD
                     IDRGGVFASLAGTMLLLNEDEKRRVKGVIINKFRGKKELLQDGVKMLEDIIKVPVIGV
                     VPYTDIKIEDEDSVTTRFKKKMNKSDIHIEIIRTPHMSNFTDFNIFETQEDVSIRYVD
                     YGESLGNPDILIIPGTKSTIDDLTYIRKSGLESQIKNLHSQGKLIFGICGGYQMLGKK
                     LKDPYHVESEIEEVDGIGLLDTETTFEKEKTTTQVEATIVECISEYMNNLKGKKVKGY
                     EIHMGITKRGNDVRSLDLITKKLDKEVNYTEGSVNKEGNVIGTYLHGIFDEISFTRAI
                     LNNIRKKKGLGELESKVNSFNEFKDKEYDKLADFLREHLDIEKIYEIMK"
     gene            121268..122644
                     /locus_tag="PC512_000121"
     CDS             121268..122644
                     /locus_tag="PC512_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobyrinate a,c-diamide synthase"
                     /protein_id="HDF2439901.1"
                     /translation="MKKILIAGTNSGVGKTTISLGIMQALVKRNMKVQPYKVGPDYID
                     PSYHTFITGRHSRNLDSYMLDDEKIKYIVNKSSKDADISVIEGVMGLYDGFGIDLDNC
                     TSSHTSKVLKSPVILVINGKSMAASSAAMVLGYKELDKDVNIKGVIVNNVKTNSHYQI
                     IKSSIEKYCNVEVLGYFPPNNKFSLESRHLGLVPSVEMKSLREKFYTLADEIEHYIDI
                     DRIIEISESDEFESDFDFQTLIENNKIKEHVNNKSIAIAYDKAFNFYYRENIELLEEL
                     GLEINYFSPLEDVSVPNADYIYIGGGFPEIFGKELEANESMRTSILEAHNNNIPIYAE
                     CGGLMYLGEKLLNQEEQEFNMVGIFSGISKMTSSLKRFGYCIGVAKENTLLSKKGESI
                     KGHEFHHSIFESDEKCVYSMRKERDGNIVEEWDGGYSKGNTLATYLHTHFYNNLNCIE
                     NFLKKGNE"
     gene            122645..123616
                     /locus_tag="PC512_000122"
     CDS             122645..123616
                     /locus_tag="PC512_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein"
                     /protein_id="HDF2439902.1"
                     /translation="MSILSIYIGYVTDLIVGDPYSFPHPVRFIGKLINFTQGIIRKVS
                     KNDRQLKLGGFILWFITVGITYLTTYAIVKLFSFNILLSIVVNSFIIYTTLATKCLKD
                     EALKIYNVLKTEDIEKSRIQLSYIVGRDTTNLSEPEIIRATVETVAENTVDGIIAPMF
                     YAFIGGAPLAMAYKAINTLDSTVGYKNKKYKDIGFASAKIDDIANYIPARISVILMTI
                     GSFFLNYNYRNCFKISIRDRKNHKSPNCAFSEGAVSGALGIQLGGTNVYFGEKVYKPT
                     IGDKLREIDKEDIIKTNKIMYASSFVSMLVFTLIYVLCRMILINLII"
     gene            123648..124718
                     /locus_tag="PC512_000123"
     CDS             123648..124718
                     /locus_tag="PC512_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDF2439903.1"
                     /translation="MKDLGHGANVDEMARLYGKNPKEIIDFSSNINPNVLPNLERYIL
                     KGLEECRNYPDINYTNLRENISKYIDINPDFIIPGNGATEVIYLLMKSIKKKLAIINP
                     TFSEYRRSAELNNLDIIDLELDLENNFKLNIDIIKENIKRFDSLFICNPNNPSGNVQD
                     LKELVHLLDKHNKVLIIDETFMEFVEDESKYSLVKYIESNKNIFIIKAVTKFFGMPGL
                     RLGYGLTSNTEIMNKIYEHKEPWTINSFADILSNFIFEDKEYIKNSKEYYIEEREYML
                     QELRNIRNIKVYDTDANFILIKIYKKTTKELKKDLFKQGNILVRDASNFIGLDDSFIR
                     VAIKSHEDNKILIENMKNLLGD"
     gene            124720..125607
                     /locus_tag="PC512_000124"
     CDS             124720..125607
                     /locus_tag="PC512_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein"
                     /protein_id="HDF2439904.1"
                     /translation="MKSYGICPASCGEFVQGIIDDEEYLCSYAIDMYSKVYIEEKLVD
                     INLGRYKSRLAIEKVFEKFNLPKKYTKNISLNINSKIPVGKGMASSTADIGATIKATL
                     SLIDKDLSSEEISKLAAEIEPTDSIFIDKNSIFNPLNGTVIKYLGNLTNAKVVILEPN
                     KVLDTMKIRLRQDYNKLKVENKEVIKKSFALLEEGLKKNNLSLVGEACTLSSLANENI
                     EKKEYLNEIIKISKKYGAYGVNIAHSGTVVGILIDKFMNDKKMIDALCESNINSVYNK
                     IYTQNIINGGIKGEIEWNT"
     gene            125595..126227
                     /locus_tag="PC512_000125"
     CDS             125595..126227
                     /locus_tag="PC512_000125"
                     /EC_number="5.4.99.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003724727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-8 methylmutase"
                     /protein_id="HDF2439905.1"
                     /translation="MEYIKNPMKIEEKSFELIQEIIDEIRPDYKFKNNIEEKIIKRAI
                     HTTADFDYLDILKISEEAVDSIIDALKNNASIYTDTNMALSGINKRKLESLGCKYKCL
                     VADDETVKLAKEKGITRSMAAVEIAAKEEGRKIFVLGNAPTALYKVMEMKSEGRLDLD
                     AVIGVPVGFVGAQESKDEVEKTDIPYIISKGRKGGSNLAAAIVNAILYTM"
     gene            126236..127462
                     /locus_tag="PC512_000126"
     CDS             126236..127462
                     /locus_tag="PC512_000126"
                     /EC_number="2.1.1.195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-5B (C(1))-methyltransferase"
                     /protein_id="HDF2439906.1"
                     /translation="MEEYVYIDGKKYRRGYTTGSCATGASKAAVYMLITKNRINTINI
                     DTPKGIPLLLKVDNINISDTFVECSIKKDGGDDIDATHTMDIYARAEIVAKNDKNKGY
                     LTLKDIDSLSTNSECKSELYKFIRVYGGTGIGVVTKKGLSVDVGKPAINPTPLKMINH
                     EIRKLIGDNFESILGNDKVLKITIFAPQGETVAKKTFNPRLGIVGGISIIGTTGIVEP
                     MSDDGWKKSLSIELQMKKEQGLDKIILVPGNHGEQFIREKLNLDIKYVVRVSNFIGYM
                     IKEAQRIGYKKILMAGHIGKFIKVSAGIFNTHSKVADARSEILVANLALMGARYEFLN
                     KINQCVTTEEAVELINNSEYREVYNILSNKCRERVKQYLNEDSDDIDVEVIIFSMDKS
                     LLGKSDNTDDLVEVFI"
     gene            127459..128067
                     /locus_tag="PC512_000127"
     CDS             127459..128067
                     /locus_tag="PC512_000127"
                     /EC_number="2.1.1.289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-7 (C(5))-methyltransferase"
                     /protein_id="HDF2439907.1"
                     /translation="MINIIGLGPGNLDYITKKGENLISTSDVLIGGKRNLESIKNFEG
                     EKIVLDSNLREIIEYINNNKEKQISIIASGDPLIYGIGRYLSKNIDNKMLNMVSGISS
                     LQYIFSKIYVDMNDVYITSSHGKVPDFDYILSHKKVCMVTDSKIGPKQISREIIDRNL
                     NKIIVVGENLSYDNEKITIAKPEEIIRMDNFDMNVVVILDEE"
     gene            128057..128632
                     /locus_tag="PC512_000128"
     CDS             128057..128632
                     /locus_tag="PC512_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating cobalt-precorrin-6B
                     (C(15))-methyltransferase"
                     /protein_id="HDF2439908.1"
                     /translation="MRNSEFITGKVPITKEEVRAISISKLNLVNAKNLIDIGAGTGSV
                     SVEAAYNYPNLKVISIEKNDDAIELIEKNKKKFNLKNIEVIKGYAPINLGLNVKVESI
                     FLGGTGNNLEEIIEWSKKNLVTGGRLVANFIIIDTFNQTLKLLKKHGFKEIDVCVLNV
                     SKLEKLGKGEYFKPLNPIYIISCEKGENDDE"
     gene            128625..129377
                     /locus_tag="PC512_000129"
     CDS             128625..129377
                     /locus_tag="PC512_000129"
                     /EC_number="2.1.1.271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-4 methyltransferase"
                     /protein_id="HDF2439909.1"
                     /translation="MNKVHFVGAGPGDKELITLKGYKLLSNADVVIYAGSLVNPELLE
                     YCKEDCQIHNSAHMDLQEIIDVMREGIENNKSVVRLQTGDFSIYGSIREQVEDLNKLN
                     IDYDCTPGVSSFLGAASSLGVEYTVPEISQSVIITRMEGRTPVPEKESIQSYAKHQTS
                     MVIFLSVQEIEKVVSKLLEGGYPKDTPIAVIYKATWADEKIVKGTLSDIAVKVKENNI
                     NKTALIMVGRFLGEEYNNSKLYDKDFKHEYRG"
     gene            129361..130482
                     /gene="cbiG"
                     /locus_tag="PC512_000130"
     CDS             129361..130482
                     /gene="cbiG"
                     /locus_tag="PC512_000130"
                     /EC_number="3.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin 5A hydrolase"
                     /protein_id="HDF2439910.1"
                     /translation="MNIEGNIAIICITENGKKLALKINSLVNNCVIYHVKNKKSNLVV
                     EETCVHTVQKKLSDFVGEIFSKFDYIVFIMATGIVVRSIAPYIISKFSDPAILVMDEK
                     GKNVISLLSGHIGGANSLTQYISSLIDANPVITTATDINQKASLDMIAKKLNAHIDNF
                     RESVKEVNSMLVNNKCVGLYIDEGYQVDTRGFKLIESKDELRDSFSNTYIEKLVVVSN
                     KINCIEDIENLNLDNKFEHCYSTKKIIKVIPRDIVIGIGCRRNTDSELMYNSLEEFLN
                     KQNIDIRAINTVGSIELKKDEKAIIELSKILKVPFKTFSVDEISKVDNLFDKSDFVKK
                     NVGVYSVAEPVAYLLSKGNLLVEKHKYKGITFSVGRIKI"
     gene            130479..131204
                     /gene="cobJ"
                     /locus_tag="PC512_000131"
     CDS             130479..131204
                     /gene="cobJ"
                     /locus_tag="PC512_000131"
                     /EC_number="2.1.1.131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011701973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-3B C(17)-methyltransferase"
                     /protein_id="HDF2439911.1"
                     /translation="MIYVVGIGPGSKDTMTLEAIKAIEDSEAIVGYKTYIKLIEEFIQ
                     DKEIIQNGMRQEVDRCKQAVEEAKKGKKVAVVSSGDAGIYGMAGLILELISKEDEDIK
                     VKVIPGVTASIGAAAILGAPIMHDFCHISLSDLMTPWEVIEKRLRLAAEADFVICLYN
                     PRSKGRSEHLSKAFKIMGEFKGGDTPVGVVKDVGREKEEKFVCTFENMDFEKVDMTTM
                     VIIGNKSTYINGELMITPRGYTV"
     gene            131201..131953
                     /gene="cobK"
                     /locus_tag="PC512_000132"
     CDS             131201..131953
                     /gene="cobK"
                     /locus_tag="PC512_000132"
                     /EC_number="1.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-6A reductase"
                     /protein_id="HDF2439912.1"
                     /translation="MILILGGTSDSLSICDKINELKNQPYILSVTTDYGRELAQQHAE
                     NVILGKLGKEDMLKFIKDNNIVKIIDATHPYAVEVSKTAITCAKLLNIDYIRFERKSL
                     IEEIDYDNKFIVDTIEEACEIANKIGTNIFIGTGSKNLNRFIEEISDKNLVVRVLPTS
                     EVILSCEKLGLSADNIVAMKGPFSQYINEETYKHYNIDLVITKESGIAGGFLEKVNAC
                     KTFNIPVIIIKRESINYENVFNDINKIKDILV"
     gene            131972..133450
                     /locus_tag="PC512_000133"
     CDS             131972..133450
                     /locus_tag="PC512_000133"
                     /EC_number="2.1.1.151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-factor II C(20)-methyltransferase"
                     /protein_id="HDF2439913.1"
                     /translation="MKKALLVVSFGTSYHETREKTIDICEDKIKNSLKSHDFFRAYTS
                     NMIINKIKKRDGIEIDNPIQALDKIYEQGYDEVIIQTLHIICGEEFNKLKEQVDGYSS
                     KFKKIVLGRPLLTHIEDYQEAVEAIKHQIPHMESNEAVVFMGHGTLHESHSAYPALEY
                     MLRDNGINAYVGTVEGYPEIEHVIRRLKEGNIKTVNLMPFMLVAGDHAINDMAGDEED
                     SWKTILEENGFNVRVHLKGLGENSYIQDKFVRHAVKCAENAKFYGIGAGPGDGSLLTI
                     KAVNTLKKLDILYTPESKKGGDSLALSIVSEYLPESVEIKSRHFPMSFDGNEKSLAWD
                     NVAQEIISDVNDGKNVGFVTLGDPMIYSTYVYIMKRILGEVEVETIPGISSFSNIASN
                     QNFPLVMDKEALVVIPCTMEDDKIEYALQNYNSIVLMKVYKNFKEIIKKLEKYDLIEH
                     AILVSNSSQESENVFTDLKEAHLEDKISYFSTILVNKDNKIK"
     gene            133480..134385
                     /gene="hemC"
                     /locus_tag="PC512_000134"
     CDS             133480..134385
                     /gene="hemC"
                     /locus_tag="PC512_000134"
                     /EC_number="2.5.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylbilane synthase"
                     /protein_id="HDF2439914.1"
                     /translation="MNIVVGTRGSNLALIQTEWVINELKKKYPEISFEIKIIKTKGDL
                     IQNVSLDKIGDKGLFVKEIEQQLLDGKIDIAVHSMKDMPSYLADGLKFAHTPKREDPR
                     DVLILREGYKNLDDLPHGAVIGTGSKRRKFQLLKQRPDLNIVQVRGNVETRIRKIKDE
                     NMHGIVLAASGIIRANLQDKISSYLPVDVVIPAPAQGALAIEIRSNDSAIEGIVNSLK
                     DENTEIQILAERGFLDGVNGSCHIPMAAYCEIIQDKIHLTGLYGDSEGKKVVIKSIDG
                     DISSPRELGLKLAKLVLKEYENYEG"
     gene            134375..135874
                     /gene="cobA"
                     /locus_tag="PC512_000135"
     CDS             134375..135874
                     /gene="cobA"
                     /locus_tag="PC512_000135"
                     /EC_number="2.1.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="HDF2439915.1"
                     /translation="MKGKVYLVGAGPGDYKLMTLKGLECIRKSDVIVYDRLANSSYLR
                     EAKPDCELIYVGKASSNHILPQEDINRIIAEKAKEGKIVTRLKGGDPYVFGRGGEEAE
                     TLVDEGIEFEVVPGITSAIGGLCYAGIPITHRDHASSFHVITGHLKGDDSGELNWNAL
                     ANNKGTLVFLMGISNLEKISENLMKEGKDKDTPVALISWATRYNQRVVTSTLENVYET
                     AIKEEVKPPTLIVVGSVVGLREKLNFFESKPLFGKSIAVTRSRNQNSVLVEKIMDLGG
                     NPIEIPTIKVEKIQNNINLENEIKNINKYNYLILTSKNAVEIFFEKIYEMNFDLRILS
                     NLKVCAIGSATSNELKKRGIIADIVPKKFVAESLYEELAPILNDDDNILIPRAENARD
                     YLVDKLKAICEVTEVHIYRTVIDEEKKGEILDILNSNDIDYITFTSSSTVNNLVEIIG
                     KENIKILEKIKTLSIGPITTETINSLGIKLYKESATSTIDSLVDLIIKN"
     gene            135891..136856
                     /gene="hemB"
                     /locus_tag="PC512_000136"
     CDS             135891..136856
                     /gene="hemB"
                     /locus_tag="PC512_000136"
                     /EC_number="4.2.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porphobilinogen synthase"
                     /protein_id="HDF2439916.1"
                     /translation="MLRRPRRLRASKAIRNLVRETKVNVEDLIYPLFVVEGENIKEEI
                     KSLPDVYHLSIDMLEDEIKEISELGIEHIMLFGVPDEKDECASQAFNDNGIVQKAIRK
                     VKEINSDINVITDVCMCQYTSHGHCGILTDTGYVDNDKSLEYLAKISVSHAKAGADMV
                     APSDMMDGRIQAIREALDENGLENVGIMAYSVKYASNYYGPFREAAHSAPSFGDRKTY
                     QMDPANSNEAIIETELDILEGADILMVKPALSYLDIIRRVKDNFDLPLAAYNVSGEYS
                     MLKFAVKEGLLNEDVILESITSIKRAGADIIITYFAKDIAKLLKK"
     gene            137009..137587
                     /locus_tag="PC512_000137"
     CDS             137009..137587
                     /locus_tag="PC512_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional precorrin-2
                     dehydrogenase/sirohydrochlorin ferrochelatase"
                     /protein_id="HDF2439917.1"
                     /translation="MLYPINLKLDELDVVIIGGGEVAYRKCKNFLEFNKNVTIVSKQI
                     LNKFYDLKGNIKIIKDDYKEIYIKDASVIIAATNNRELNMEIGLYCKAKNKLVNVVDN
                     IEISNFTVPSYIKRGDLLISVSTGGKSPSLSSKIKKEIEERYTEDYEEYLNVLGDIRK
                     KVIKKYEDKSKRKDVLNMLVTLDLEELKKFDI"
BASE COUNT        55079 a        14738 c        24950 g        42858 t
ORIGIN      
        1 ttttttgtca aaaaaaacaa aaaatacgta tttctttttt catttcggga aaactaaaca
       61 caggaattat ggactttata aaaatttaat tcttgaggag tgatataagt gaaaaaagtt
      121 gctttaattt tagctataat aggtgcgctt aactggggtg caattggtat tctaggtaca
      181 gacttaatag gtagtatctt tggtggaaca tatgaaatgg taagtagaat aatatacttc
      241 attgtaggtt tagctggatt atacttaata ccaagtttaa tgtctgatga tagagaataa
      301 tttatgcttt tatgttaaat acctcattct aaatgtttag aatgaggtat ttaattttat
      361 aaaaatatta atttgtttct tttttaatgg taaaatagat aagaattgaa gttttaaaaa
      421 gaagtattat gtaaaaaagg agtactatta atatatgttt attattaatg aattaaataa
      481 gattgtaaat gaagaagtaa tatcttttca tatgcctggt cataaaaagg gacaggttta
      541 taaaaagtta ggatataaag atatactaaa aaatttgtat aaaatggata caactgagat
      601 attaggaaca gataatttac actttccgga aggaattata aaaaattcac aaaaaaaagc
      661 atcaagagta tttaaaagtg attatacttg ctatttagta aatggtagta gctgtggaat
      721 acaatctgca ataatgtcag tatgtagtcc taaaagtaaa ataataacaa atagagactg
      781 tcatcagtct gttataaatg gatgtatttt aggagatata gatatagagt atgtgccttg
      841 tgagataagt gaagagacaa atatcttaaa agggatatct ataagtaatg tgattgatat
      901 aatagataaa aacttggatg caaaagcagt actgcttact tatcctacat attatggaat
      961 gacatatgat ttagaataca tatgtaatta tgcacatagc aaaaagatgg tagtgatagt
     1021 agatgaagca catggtgcgc atttagggct tagtgagagg cttcctaaaa cagctcttga
     1081 gcaaggtgca gatatagttg tacagagtac acataaaact cttccagcat ttacacaatc
     1141 gtcaatgata catatacagg gagaccgagt tgatatagat aaaatattga acatgttaag
     1201 aattacagaa tcttcaagcc cttcatattt attattatct tctctggaat tagcagtaga
     1261 tatatatgaa aataaaggaa aagaattaat ggaagagctt ttaaataata ttataacttt
     1321 caaaaataaa gttgattcaa atattaatat atacgacaca aatgataaaa caaaaatatt
     1381 tatatcatct aaaaacatgg gtttaacagg ttatgaacta gaaaatattt tgagaaataa
     1441 atataacata caagtggagt tatctaatta ttatggagtt cttttaatat gtacaatagg
     1501 aaatactgct gaggatttct ctagtttaga aacagcatta aacaatgttg taaaggaaga
     1561 ctttaaattt gaaaagttag aaaataaaaa ataccctgtt gttattccaa agaaaatatt
     1621 aacacctaga gaagcatttt ataaaactaa aaaaagtgtt aaaatatatg acagtatagg
     1681 taaagtttgt ggtgaatgta tagttccata cccacctgga ataagtgtaa tatctcctgg
     1741 tgaagtaata agtaaagaaa taatagacta tctaatgttt tgtcattcta aaggcatgat
     1801 tgtgagtgga ttgaaagatg tagatttaaa ttttatacaa gtaatagatt tagaagacat
     1861 ttaaaaatta tgatataaaa gtagatagaa gtagatagtt taaaattgtg aagagaaata
     1921 aatagactgc ttatatagag atatctaata aaagtactaa aaaagtaaaa agtgtttgta
     1981 tggaggatat gaaaatgaaa ggtaagttaa taattataga gagtggttca gatgcaagtg
     2041 gaaaggctac tcagacagaa atattatatg aaagattaaa aaaagaaggc tatatgatta
     2101 aaaaggtaga atatccaaat tatgaatctc catcatctgc cttggtgaaa atgtacctaa
     2161 aaggagactt tggtaaaaat gcatcagatg tagacccata tatagcatca acttttttta
     2221 cagctgatag gtatgcatca tttaaaaccg attgggagga gttttacaat gaaggtggaa
     2281 taattatcgc agatagatat acaacctcta atatggtaca tcaggcctct aaaatggata
     2341 tttgtgatag agaagagtat ttaaattggt tagctgatta tgaatttaat ttatttaaga
     2401 taccacaacc tgattgtgtt atatttttag atgtgcctat tgaatttagt aaaaagctta
     2461 tggagaatag aaaaaataaa attacagggg aagaaaaaaa ggatattcat gaaagtgaca
     2521 tagagtattt agagaaatct tacaacaatg ctttatatat agcagataaa tatgattgga
     2581 aaaaaataaa ttgtgtttta gataacaaat taagaagtat tgaaagtata cataatgaaa
     2641 tttataaaat agttcttgat tcaataaaac ctatggagag ataaatatgt attttgaaaa
     2701 tattataggg caagattttg caaagaaata tttaacaaat tctataaaga aaaataaact
     2761 taataatgcg tatatgtttg aaggaatgga tggaatagga aaaaagaaat ttgcagatga
     2821 attatcaaaa ctattacttg attatgaaaa tctcgaaaat agtccagact atgtactcat
     2881 aaaaccagat ggaaatagta taaaaatagc tcaaatcaga aatttacaat cagatatagt
     2941 aataagacct cataaagact ataaaatata tataatcaat aatgctgaaa aaatgactgt
     3001 ggaagctcaa aatgcacttt taaagacgct agaggaacct ccaaactatg ctataataat
     3061 cttagttaca aacaacaagg aatctttatt agaaactata aaatctagat gtgatataat
     3121 aaagttctca cctataccaa ttgaagactt aaaacgttat ttgataaata caggtataga
     3181 agaagaaaga gctcaattat tggctatttt ttcgagagga agtattgaga atgctctaaa
     3241 tctatctcag tcttctgagt tttcaatgat gagagaagat atacaacagt atattcagat
     3301 aatgttagat aaaaacatag tggagatttt aaatatacca aataatatgg aaaaatatag
     3361 aggtaagatt atagctttat tagatatgat gataaactat tttcgagata tcatcctatt
     3421 aaaagaaaat gtaaacaaga acatgttaat aaatgtagat aagctagttt tcattcaaaa
     3481 tatgaatgga aaaattagtt attctcaatt gtccaagatt attgatataa tagaagatgc
     3541 aaagagtaaa ataaaaagca attgcaattt caatataagc atacaagtta tgtctttaaa
     3601 tatatacgag gtgattaaat gataaagata gtaggtataa ggtttaaaag tgctgggaaa
     3661 atatattatt ttgaccctgt tgattttaat atagagcaag atatggatgt agttgtagaa
     3721 actgcaagag gcttggagta tgggaaagta gtcgttggtc caaaagatat ggatgaaagc
     3781 gaattagttt ctcctttgaa gccaattata agaatagcta cagaagaaga taaaaaagta
     3841 tatctagaaa ataaggaaaa ggcaaaagaa acttttgagt tgtgccaaca aaaaataaaa
     3901 gaacatgagt taacaatgtt tttaatagat tgtgagtata catttgatag gaataagttg
     3961 attttttact ttacagcaga aggaagaata gattttagag aattggtaaa agacttagct
     4021 gctatattta aaactagaat agaacttaga caaataggtg tcagagatga agctaaatct
     4081 ataggaggtc tagggccttg tggtagaaaa ctttgttgtt catcttggtt aggtgatttt
     4141 caaccagttt caataaaaat ggcaaaagac caaagtctat ctctaaatcc aacaaaaata
     4201 tctggaatat gtgggagatt attctgttgc ttaaaatatg agcatgatgt atatagtgaa
     4261 gcaatagaaa aaatgcctgt tgtaggtgca ttggtgcaat cagatgatgg aaaaggaaaa
     4321 gttgtagaag tgaatccttt attagaacaa attaaagtgg aatttcaaga caagacagta
     4381 aagatataca caagagaaga tataaaaata cttagagagc ctaaaaaatg tgatggctgt
     4441 ggtggtaaat gtaaggataa tgatggatta gatgaagcca cactaagaga gctaaagaaa
     4501 ttagaagatt aaatttaagg tagggctttt cctacctttt ttaaagcaat taatgcttaa
     4561 agttattaat atttgaggag aatttatata tgcaattaaa agattcagaa agaatagatg
     4621 atttacaatt aaaaggcctt aaaattatac aagatactaa tggtttttgt tttggtatag
     4681 atgcagtttt attagccaat tttactaaaa taaaaaaaga tgccaaagta gtagatttgg
     4741 gtactggaac tggcattata cctattttga tagctggaaa aagtgaagct aaaaaaatta
     4801 ttggcgtgga aatacaagaa gatgtatatg aaatggcaac tcgttctata aaattaaatg
     4861 gattagaaga aagagttgag attataaatg aagatataaa atacatagac aaagtcttag
     4921 acataaatgg ttaccatgta gtcacatcaa atcctccata tatgcatatt gatggaataa
     4981 aaaatccaaa tgataaaaaa gcaatatcaa gacatgaagt aaggtgcaat ttggaagatg
     5041 taattagagc tgcatccaga ttggttatgc ctagaggaaa attcttcatg atacatagac
     5101 caacaagatt ggttgatata ataactttag ggagaaaata taaattagaa ccaaaggtta
     5161 ttcaatttgt gcatccaaga cctcaaaaag caccgaactt agttttggtt caatttgtaa
     5221 aagatggaag gccagagctt aaaatattgg acccattgta tgtttatgga gaagatggga
     5281 attatacaaa agaattaaaa gcaatatata ataataaaga tataggagag ttgtaaatga
     5341 gcgggaaatt gtacatatgt ccaacaccaa taggaaacct agaagatata acatatagaa
     5401 ctttaagaat attaaaagaa gtagacttga ttgcagcaga agatacaaga catagtataa
     5461 aacttttaaa tcattttgaa atctcaaaac cactaactag ttatcatgaa cataataagg
     5521 attcaaaggg agattatttg ataaataaac taattgatgg tgaaaatata gctctgataa
     5581 gtgatgcagg tatgcctggt atatctgacc caggagaaga gataataaaa caagctatac
     5641 aaaataacat agagatagaa gtattgccag gtgcaacagc ctttgtaacg gctttagttg
     5701 gctctggtat ggacacacat agatttattt ttgagggctt tttagataga gataaaaaag
     5761 ttaggaaagc acaattggaa gaattaaagg aagaaagtag aactataatt ttctatgaat
     5821 caccacatag attgaaggat acactaaaag atatgcttaa aattcttggt aataggaata
     5881 tttctataaa tagagaactt acaaaaaaat atcaagaaat aataagagaa aatatagaaa
     5941 ctaccataaa aatatttgag gaaaaagaag taagaggaga gtttgtatta atagtagagg
     6001 gttttcatgg tgagaagtca aagaaagaaa attatgatgg gcttacagat agggaatatg
     6061 ttttaaaact aattgaaagt ggtatgaaca aaaaagatgc aataaaaata gtttgtaaag
     6121 atagaaagtt aaagaaagat gtggtttata aacaagtttt agatttataa aacctgaatc
     6181 tgaggtgatt ttatggaaat agggaaaatt ataatagaga gtttaaagag ggaagataca
     6241 cataaaatat ttatagaatt agataataag catgaattag aaaaaataat tcctaaaata
     6301 agctgtatga agtctgtagg tgaatgtaaa tatcatgtag taaattgttt tgaacattct
     6361 ataaatgcat taaaagaatt agaaatagta ttaaatgata aggatttttt tccaatacat
     6421 ctaagaaaac atgtgtcaaa ctatttaaaa acatatattg aagaaggaat aaataagtta
     6481 catgtattaa agctgggaac atttttacat gatataggta agcctgacag tatgacctta
     6541 gatgaaaccg gaagagttca tttcacaaat catgaaaaaa taggtgctca aataattgac
     6601 aatatgggaa taaagttaga gttatcaaca gagacatata gacttataag taaatatgta
     6661 agatatcata tgatactttt gtctctatat aagaaaaatg atttgagtag gaaagaatta
     6721 attaatgtat ttaacttagt agatgaggac actataggtg taataatgct tgggtatgca
     6781 gatatagtgt ctacagtaaa attattgggc aagagtggag aagtcagtgt gttaaagaca
     6841 tatatggaat atattttaac aaattacttg tataagagta attatacaca tgtataaatt
     6901 tagttaatat aattgagttt tagatgatta attgaagttt gaaatatacg gatttcaaaa
     6961 acataaaaga agttgtcttt gttgtaaaat tatgaaagac aacttttttt atatcaaaaa
     7021 ttgaaatttt attaaggata cttaatggtc tattaattaa taaaccatta gtatttaatt
     7081 tatattacaa tattgatttt gcttgtattg gcgttgatag tataacagag gtcttagtag
     7141 aaccaatttt ctttatagta tcaatcacat tttctagctc gtacatatct tttacaatta
     7201 cttttaaaag taagcaatca tcacctgtta tatggtgaca ttctacaatc ctagggtcct
     7261 ttgcagctga ctcaataaat tctgtatatc cattgcttgg aagagaaata tgaataaatg
     7321 cctttataac tctgcctaat gaatctgggt tgacaatagc tttatatcct tctataacac
     7381 cagactcttc taatcttttg actctttctg aaactgcagg agaagttaaa ccaactattt
     7441 ttcctaagtc cttcatagaa attctcccat catcctgtaa aatttctatg attctgtaat
     7501 ctgtaacatc cataaataaa cagtccccct taaataaaaa taattaatgc tataaaactt
     7561 ttttagaatc tatcatttgt gtttttaaat accaaagatt tctagataaa tcaaccttat
     7621 aaatgtgtgg ttttgaaagt cttttgtatt gttcccagat agtacttaat tcatattgta
     7681 catgattttt tatttcaaga acagcttttt tattatattt gcatctgcct tttatataca
     7741 atggtttaag aagctcttta actttgtaat ttgtaaatac cttcgttttc catgtataag
     7801 taggatggaa gatttctaaa ggtttagact catctataac ttcatcatgt aacataatca
     7861 aatctgcctc tgccttattg tcttcgttat atattcttat aactttcttg taaccaggat
     7921 tatttatttt ttctggattc tcagaaatct ttatcttagg ttcaagaact cctttttcac
     7981 aagatgcagc taatttataa actcctccaa gagaaggtga atcgaaagat gtaatgagct
     8041 ttgtacctac tccccatgaa tttatagtag ctccttctgc tttaagtgat gttatggtat
     8101 attcgtctag gtcattagat gcagttatgc tgatatctga aaagccagca ttatctaatt
     8161 gttttttagc ttctttagat aaataagcta aatctccaga gtcaagtctt atacccatag
     8221 gtttgtatcc tttttcagaa atatttttga atacttttat tgcattagga actccactgt
     8281 ttaatacatc ataagtatct acaagtagta ggcatttatc tggataaaca tcagcatatg
     8341 cttggaatgc ttcaagttca ttatcaaatt tttgtaccca actgtgagct tgtgtaccaa
     8401 ttataggtat atcaaacatt ttccctgcta gtacgtttgc agttccagca caaccaccaa
     8461 ctacggcagc cctagcccca tatatccctg catctggacc ttgtgcacga cgtaatccaa
     8521 attcaaatac agggtctcct tgagctgcaa agcaaactct agatgcttta gtagcaataa
     8581 gagactgaaa attaactatt gttaacaatg ctgtttcaat aagttgagct tgatataaag
     8641 gtgccttaac agtaattaat ggctcattag ggaacatgat agttccttcc tcaacagcat
     8701 atatatctcc tgtgaattta aattctttta aaaattttaa gaacttgtca gaaaataaat
     8761 ttaagttttt taagtactct aaatcttcat ctgaaaaatg aagattatct atgtattcaa
     8821 caacctgatc aataccacaa actatagtat accctccatc acaagcgttt tttctaaaaa
     8881 acatatcaaa tacaacaatg tcttcatgaa tattcttttc aaaatagcca tttaacatag
     8941 taagctgata taaatcagta agaagtgtta gatttctcat tatttctctc cttaattatt
     9001 attaaatatt aaaaattgta aaaactccca cacttatact aaaacataat atagtacaac
     9061 tttcaagtat aaagtattac ctaactatca taaaattatt taaagaggag gatgattata
     9121 ataggaaaaa tatggtttta tatggtatcg ataggaataa taggaagctt gatttctaaa
     9181 aatatgggtg aattaaataa agttatatta agtgaaacat caaaaggtat agagtttgca
     9241 ataagtctag ctggtatcat ggcactctgg atggggataa tgaatatcgc aaaagaatca
     9301 ggtttaattg aaaagatagg tcaaaaacta aatcctataa tgagaagatt atttccttct
     9361 attccaaaag gtcataaagc aatgtcttat atagttatga atattgcttt aaatatgttg
     9421 ggtgctggaa atggtgcaac agcatttggt ttaaaagcaa tgagtgagct tcaaactttg
     9481 aataacaaga aagatacagc cactaatgat atgattatgt ttatggtaat caatatatca
     9541 tctatacaaa taattccatt tactataatc aaactaagga tggatatggg ggctcaaaat
     9601 ccaagtgaaa taatttttac gactttattt gcaaccataa tatctacagc agtagcaata
     9661 ataacatgta aattttttca aagaagatat agataaaggg gatgtagata catggagata
     9721 ttttcaaact tacttatacc aataataatt ctgtacatag tagtttatgg taaatataaa
     9781 aaaatagatg tgtatgatag ttttgtaaaa ggagcaattg atgggttaaa agcagcatgg
     9841 gatatcctac catatataat aggtatattt ttggcaatag gaatattcaa aactggtaaa
     9901 ggtcttgata tgttagaatg gctatttaca ccaatagcaa atatgatgag tataccaaaa
     9961 gaattaatag gtctaataag tgtaaaacct ttatctggaa gtggtgcttt agggatgtac
    10021 agtgaacttg caaatagagt tggaatagga agtttagtag aaaaaatggg tgctacgatt
    10081 gtaggttctt ctgagactat tttttacaca atggcaatat actatggaag tctgaagata
    10141 aaaaatacta gacatacatt atcatgtgct atgattagcc atgttgcagg tgtcatagca
    10201 gctgttttta tttgctatgt aatatttgta taatttgttg acaatatggg aaaaatttta
    10261 taatatagtg attatataga aacaaatagt aatacaaatt acaagctatg aaaagaagag
    10321 taaataaagg ttttttctat cagagagcta ggttaggtga aagctagtgt caaaagcttt
    10381 attgaagatg gtcttggagc tttttatctg agcaagtgtg ctagggtaaa acggttggac
    10441 acgttatagt ctactaaggt atctataaaa tgtttctaca tttcatgtga aacataacta
    10501 ttatagatga attagggtgg taccgtgaat aatctcgccc ctatgttaac tcataggagg
    10561 cgatttttta ttatttaaat gaaagaatca tatgattacg aacgataaaa aattaggagg
    10621 taaataacat gagcaaaccg agtttttatg taacaacacc aatatactat ccaagtggag
    10681 gattacacat aggacatact tattcaacag tagctgcaga tacaatagct agattcaagc
    10741 gtttctgtgg atatgatgta aagttcttaa caggaacaga tgagcatggt gaaaaaattc
    10801 aaaagaaagc catagaacaa ggaatgtcag agatagagta tcttgatgga atgataaaag
    10861 atataaaggc cttatggaat actatggata tatcttatga tgattttata agaactacag
    10921 aaaaaagaca tacagacata atacaaaaga tatttactaa actatatgag caaggtgata
    10981 tatataaagg tgaatatgaa ggtagatact gtactccttg tgagagtttc tggacagaat
    11041 ctcaattact agaaggaaat aaatgccctg actgtggaag agaaacatat ttagtaaaag
    11101 aagaatctta tttctttaga ttatctaaat atgaagacag attaaaagag ttatttaaag
    11161 atgatagttt ctgttttcct gctgctagaa aaaatgaaat ggtggcaaac tttttagaca
    11221 aaggattaga agatttaagc gtaactagaa cgacttttga ctggggtata aaagttcctt
    11281 ttgatgaaaa acatgtaatt tatgtgtggg tagatgcttt atgtaactat ataacagcat
    11341 taggttatat gactgataat gatgaagaat ttaaaaaata ttggcctgcc aatgttcaaa
    11401 tagtaggtaa agaaatagtg agattccata caataatatg gccagcgctt ttaatggctt
    11461 taggtctaga agttccaaaa caagtatttg gacatggatg gatactattt gctgatgata
    11521 aaatgagtaa atcaaaaggt aatgtggttt atccagaacc tataatagaa agatatggaa
    11581 tagacacact taagtacttc ttattaagag agtttgcatt tgggcaagat ggaagttata
    11641 ctcatagaaa ttttgtaacg agaataaatt atgatttagc aaatgattta ggaaacttaa
    11701 taagtagaac tgtagctatg gttgaaaaat acaataatgg tataatacca acagcaaaag
    11761 tttcaactaa ttttgatgct gacttaaaag aacaagctgt ttcaactaga gaaaactttg
    11821 aagctgaaat ggataaaatg caattccatg aagcattaga gagtgtatgg aaattagtta
    11881 gaagaactaa caaatatata gatgaaacta tgccttgggc actagctaaa gatgaaacta
    11941 agaaagatga attagacaca gttttatata atttatgtga atctataaga ataatcgcaa
    12001 cactaataaa tcctataatg aatgagactg ctaataaaat atatgaacat ataggaataa
    12061 aaggtcaaga tgatataact acatgggaaa gtacaaaaac atttggtctt attggagaaa
    12121 atgtaaaagt atttaaaggt gaacctttat tcccaagatt agatgtagaa aaagagatag
    12181 aagaattaac taaaatgttc tctgggaaac ctccagtaga agaaaaacct ttagagcata
    12241 aagaagaaat tactattgat gatttagaca aaatagagct tagagtaggg aaaataataa
    12301 gctgtgaaaa acatccaaaa gcgaataaat tattagtatc acaagttaag attggaccag
    12361 aaacaagaca aatagtatca ggaatagctg aatactataa gccagaggat ttagtaggaa
    12421 aagaggttac agtggtatgt aacttaaaac cagttaaatt aagaggtgta gaatctcaag
    12481 gtatgatatt agcagcaggt gatgatggag acccatatgt tttaccattt acacaagggg
    12541 ctaaagatgg atgtgaggtt cgttagtagg taattaaata gtaaggagat taaagatgtt
    12601 atttgactca catgcacatt taaatgatga aagttttgat gaagatagag atgaacttat
    12661 tggttcatta aaagataaag gtgtagattt ggttgtaaat ccaggagcag atatagagac
    12721 gtcgataaca gcaattgaac ttgcgaaaaa atacgacttt atatattcag cagttggggt
    12781 acatccacat gatgtatcaa aactagatga tacagcaata gaaactctaa gaaaacttgc
    12841 aactgagaat gaaaaagttg tagctattgg agagattgga ttagattatt attatgatta
    12901 ttctccaaga gaagaacaaa aagagtggtt taagaagcaa attgaattag ctaatgagct
    12961 aaaacttcca ataataatac atgatagaga tgcacatgga gatacttttg agataataaa
    13021 gaatactaaa aatcctgaaa taggatgtgt acttcattgt tatagtggga atgtagagtt
    13081 agctagagaa tatgttaaga tgggttgtta tatatcaatt ccaggtacgg ttacttttaa
    13141 gaataataaa aaaactagag aagtagtaag agaaatacct ctagaaagat tattcataga
    13201 gactgattca ccatatatgt caccagagcc acatagagga aagagaaaca atccttctca
    13261 agtatctttt gttgctgata agatagccca ggaaaaaggg atatcttatg aagaagtatg
    13321 tagagttaca aaagaaaatg caaagaaatt ttttaatata aaatagacaa attaaatctt
    13381 ataatgatat atataataag tcattataag tataggatga gagtgcctca aaatgagttt
    13441 tttagtttat gaggcactct ttttgtatga aatcaaatat attttcatca tttcaacaat
    13501 gaaaaagaag tttatcatat tttgagatag tttgttttta tttatttaat tcatatttta
    13561 aaatatattt tcttaacatt gttaaaaaag aatttacaag atattcatta gaattaactc
    13621 aactctaata ttcacttaac ttaagttgtt tattatatta ttaaagagaa gtaaacgaaa
    13681 agtagattaa ggaggttgaa ttttgtatac agttgatagt actaagatat tgataaatat
    13741 gaacttagag aaactagaaa agatatactc aatgataaaa gatacatcaa gtatttctat
    13801 aattaaagaa cctaacttgg ctacagtaat ggtaagagct aatgaaagtg taaaaaacac
    13861 aacatttaat ttaggagaga tattagttac tgaatgtagt gtaaaggtag atgaaagctt
    13921 gggttacgga atagtttcag aaaacaataa taagaaagcc atttatttag cagttataga
    13981 tgcagtttta catagcaata acagtaaatt tgatgagtta aagaattaca taaataaaag
    14041 tgtatatgaa gagaacttaa ggtatgaaca agagattatt gatgaattta gcttgattaa
    14101 taaaacgaaa gttcaattca atgctatgga ttaaatagga ggagaatcat ggtaaattat
    14161 acacaagaaa tatatagaaa gatgctagat agtgcttcat ttcctgggaa attaaataat
    14221 atagataata taaatataga aaataataca aaactattga atggagcaat tggtatagca
    14281 atcactttat tagaccaaga agttaccttc tatatagaaa attatactca aaaagatata
    14341 aaaaatataa gagcacttac aatgtcaaat caaatagatt atagaaaatc agattatata
    14401 tttttagata ttaattcaga agtggatata ttacagatta aaataggttc ttttgaatat
    14461 cctgatgaaa gtgcaactat agtacatcaa gtaaatgatt tatcaacgta ctctcaaact
    14521 aagtatataa agcttgattt gagtggtcct ggtataaaat ctaaaaatag tatatatata
    14581 aatggaatta gagaagaatt tatagaaaga ttatctagca taaataaaga ttatccaata
    14641 ggaatagatt tgattttagt agataaaaaa ggagaaattg catttatacc aaggtcatca
    14701 aaattaagtt gggaggtatt atagaaatgg cttatgtagc agttaaaggt ggagaagaag
    14761 ccatattaca ggctaaaaat atacttgagt tttatagggt aaaaggagat agcttgccta
    14821 tagatgtaaa gcagattgag gaacaaatgt cttatgctgt agacaaagta atgtctgaag
    14881 gaagtttata caacaaggaa ctatcagcat tggctataaa acaagctcaa ggtgatatat
    14941 tagaagcctc tttctatgta agagctttaa ggtcaacaat gcctagaatt acatattcag
    15001 aacccataaa tacagaagaa atgagaataa aaagaagaat atcagctact tttaaagata
    15061 taccaggagg tcagtatctt ggggcaacta gagactatga aaatagaata ttgaatgtag
    15121 aattattaga agaagatgaa aaaaagaata gacattttag agatagtttt ataaatgaat
    15181 tagaaacagt agatgaaatc cctgaattta caaaaatatc taatatattt agaaaagaaa
    15241 atttattaca agaagaagtt tgtgaaaaca aattggaaga agttattgat gatattacaa
    15301 gaaatagttt aagatttcca gtttctaggt cagcaaagtt acaggcatta actagaggtg
    15361 aaagtggagt agtgtcaggt tttgcttatg ctattgtaag aggttttggt gatgaacatc
    15421 catatataag tgaacttaga actggtaatg tatttataaa agtaaaacat cccatctatg
    15481 aagatgaaga aataataata ggggatatgc tggttactga atgtgaaata gtttcaaaag
    15541 catcacaaaa taagactgaa aattctaaaa ctaattcgga agataaaaat aagatgtctt
    15601 taggatatgg tctttgtatg gggaataatg agaataaggc tatatctatg gccatactag
    15661 acaaatcttt ggagccaaat agtgaaaaac tagcacaaga tgaagaattt gtattgcttc
    15721 atatagatgg aatagattca ttaggattta tatctcactt taagcttcct cactatgtag
    15781 attttaaagc ggatgtagaa agaataaaat agtttgagga ggtaagttta ggtgatatat
    15841 aactatggtt ttttagacga aaacacaaaa aaagaaataa gaagaaagat attaaaagca
    15901 atatcaatac ctggttatca agttcccttt ggttcaagag agttgcctat agctaaggga
    15961 tggggtactg gaggtttaca attaacacta tcattaattg gtaaaaatga tgtagtaaaa
    16021 gtaattgacc aaggaagtga tgattctaca aatgcttgta atataaggag ctttattgca
    16081 agtgtaagta atgtagaaac cacaaaagat acattagaag ctacattgat tcaaacgaga
    16141 catagaatac cagaagaaaa acttaaatct aatcaaatac taatatttca agtaccaata
    16201 ccagaaaccc ttagaatagt agaacctagt gaagtagaaa caagaagaat gcattcagaa
    16261 gaagattata gtaggatgtg ggtatatctt tatgaagata tagttagatt taatgatata
    16321 tctatagcag ttgaatatcc atgtaaagta aatgatagat atttaatgaa tccatcacct
    16381 atacctagat ttgatataaa aaaattaaat atgtcagaca atttattctt gtttggtgca
    16441 ggtagagaaa aaagaattta tgctattcct ccatatacaa aggtagaacc tttagagttt
    16501 gaggattata agtttgaaga ggaaaagttt gaaggaaaat actgtagttt atgtaacagt
    16561 acaaatacat ttttagatga agtatatgac agtgacacta atgaaaagta ctatagttgc
    16621 tcagatacaa gttattgtga aaaagttaga ttaaaaaata acagtataga tgtgacaata
    16681 ggaggtactt ggaatgagta aaataaatga ctctaaaaga ttagaaaata tagacaagca
    16741 agtattaata ggaagaaata tcaatcttat ttatggagat gggtgtgaaa agtgttttga
    16801 aagcacagga tatgaaagca ataatatatg taagtattgt ggttctatag ttgcatgtaa
    16861 taatgtaaat ttagaacttt atgaaggaga agtccttgga attgtaggtg aatctggttc
    16921 aggaaaaagc actttattaa aaatactgtt tttccaagaa catgcaaata gtggagaagt
    16981 atatatatcc cattacaata aagacacaaa tatactagag ctttcagacc aaaaaaagag
    17041 atacataaag aatcatttta tgggtattgt gtatcaaaat ccccaccttg gtttaaattt
    17101 agactttagt agtggtggta atatagcaga aaaattattg atggcaaatt tatataatgt
    17161 tgaaaaaata agagatagag gcaaagaact tttaataaaa actaatatac ctgtagaaag
    17221 aatagaccat aaaccaaaat actttagtgg gggaatgcaa caacgagttc aaatagcaaa
    17281 agctctttca aataaccctc caatattgct attagatgag gttacaacag gtttagatgt
    17341 ttctgtgcaa gcggaagtat tggatttaat aagagaaatc caaagagaac ttaagatttc
    17401 tatgatagtt gtatcccatg actttgatgt tataaagatg cttgctgata ggacaattgt
    17461 aatgaaaaat ggaagtgtaa ttgagtctgg tcttacagac caaataatgg aggacccaca
    17521 acacccatat actcagcaac ttataaattc attgctataa atatcgtttg taaataagca
    17581 aaatgggggt ttttaataaa atgaaagaaa ctatacttga agtaaataat tttagtaaag
    17641 actttgagtt acatgcattg aacaagacta taacggcatg tagtaatata agttttgaag
    17701 tttcaaaagg tgagttttta ggaataatag gtaaatctgg agcaggtaag tctaccatat
    17761 taaaaagtat ctataaaaca tatataccaa caactggaga aataattttt aattcagaaa
    17821 tatatggtaa tgtagacctg gctaaaattg gagaccgaga aatgataaat cttagaaaga
    17881 aagaaatagg atatgtatca cagtttttaa agacacttcc acgaataact gcaattgaac
    17941 tggtagtaca ttctttaatt gagagtgggt ttgaaaaaga ttgttcgtat gatatggcaa
    18001 aagatatact taaccaattt gaaataaagg aaaatttatg ggatgcgtat ccaaataatt
    18061 tttctggtgg agaaaaatta agattaaatt tagctcaagc tatggttaaa aagcctagac
    18121 ttttgttact tgatgaacca actgcatcac ttgataatca atctaaaata tatgtaaaag
    18181 aaaaaatgtt ggagcttaaa agtcaaggaa ctacaatgat aggaattttt catgatatag
    18241 agtttatgga aactgttata gataagacct ttactatgac aaaagggact ataagtgaaa
    18301 gtggggtagc ctagatgata aaactaattc ataatgcaaa tattgtatta gaagatatga
    18361 ttttagaaaa tggtcattta atcatagagg gagatacaat aaaaaaagta tcaaatgata
    18421 agattgatta cgcatttgac tttaatgaga tagatgaaat aatagatgca aaaaacttat
    18481 atgtaatacc tggtattata gatattcaca gtgatgccat tgaaaaggaa atagagccga
    18541 gaccaagtac attattacca tttaatatgg cattttatga actagataaa aaactacctg
    18601 caaatggaat aactacagtt tatcattcta tatctttagg ggatggagta ggagttagaa
    18661 gtattgataa ctctttaaag atgattaaaa atattgattc atataaaaat atagatagta
    18721 agagcataaa tcataaagtt catttaagat atgaagtgtt gtattatgaa ggtttagaaa
    18781 aggttttaga actattagat gaaaataaaa tagactactt atcaataatg gaccattctc
    18841 caggacaagg tcagtataca aatccaacat tttataaaga gtatgctact aaagtgtggg
    18901 gagttacaga aaattatgta gatacatggt tagatgattt agtaaatctg catgataatt
    18961 tagattggaa taaaatagct aatattatag gtatagccaa aactaaaaat ataaatgttg
    19021 catcacatga tgatgataca ttagaaaaaa tggatttcat aaaaaatata ggcataaatg
    19081 tatctgaatt tcctataact cttgaagttg caaaacattc aaagaaattg ggtgttctaa
    19141 cttgtttagg tgcaccgaat attgtaagag gtaaatctca taataacaat ttaaaagcaa
    19201 tggatgctat attggaagat tgttgtgaca ttgtgtgttc ggattatctt ccatcagcta
    19261 tgataaagtc tatgtgtata gttgcagaaa gaataaataa tttaaataaa gcagtcagtt
    19321 tatttacctc aaatcctgct aaagcagttg gtatatatga tgaaagaggt agtataaaag
    19381 aaaataaaaa agcagattta gttttagtag atattgatag tgaatatcca aaggttgtaa
    19441 atactattgt aaatggaaaa acagtttata aaagggaggt ataaagattg ctaacagagt
    19501 tacattgtca tacaagtata tcagataata attttactac tgaagaaata ataaaaaaag
    19561 cagcagaaaa gaatataaat atcttagcaa taacaaatca tgacacatta tctggattgg
    19621 atgaagctct tgtgcttgga gagcattatg gaataacaat aataccaggt atagaaattt
    19681 cagcctatga ttataaaaat agaaaaagag ttcatattct tggatataac atagatttaa
    19741 acagtcaaga aataaaaaat ttgtgcaatc caatggtatg tgacagacat aaagcatctg
    19801 ttaagatggt aaataaaatt atagatttag gatacaaaat atctctggaa gatgtaaaga
    19861 aatattcatc aaagactgga atatttaaac aacatataat gaaagctctt atagataaag
    19921 gatatacaga taatatatat tcaaatctat ataaagaatt gtttcataga ggaaacggca
    19981 aggtatatgt atctttaaaa tatgtggatt acagagatgc aataaaagct ataaaaaatt
    20041 ctggtggaat ttgtgtgtta gctcacccgg gtcaaatgga taattttagc gctattgaag
    20101 agatggtaaa agtaggatta gatggaatag aagtatatca tccatctcac aacaaagaac
    20161 tagaaaaaga gtcgctttct tatgctaaga agtataatct agtggtcaca ggaggttcag
    20221 attaccacgg attttattct caacataatt atgaacttgg aagcaagagc ttaaataaag
    20281 aagatttatt taagtttagg ttagctttag gaggggtatt ataaatgtct tttttacaag
    20341 taaaaaatgt aggtaaaagt tatggacaag ttaaggtgtt aaaagacata tctattgata
    20401 ttgaaaaagg agagtttatt tgtttactag gtccaagtgg ttgtggaaag agtacactac
    20461 ttagaataat tgcagggctt gaggataaac atggtggaaa aataataata aatgataagg
    20521 atatgactaa ttcaccacct gaaagtagaa attttggtat agtttttcaa tcatatgcat
    20581 tatttccaaa tatgaatgtt tacaaaaaca tagcctttgg actagaaaat aaaaacataa
    20641 gtaaatctaa tattgataaa aaagttaaag aagttctaga agttgtagaa ttaagtggat
    20701 atgagaaaaa atatccatca caattatcag gtggacaaca acaaagggtt gcattagctc
    20761 gtgcgattgc tttagagcca gactttttac ttcttgatga acctttatct gcattagatg
    20821 caaaagtaag acttaaactt agggagcaga ttagaagttt acatagaaaa ctaggcatta
    20881 caactataat ggtaacgcat gaccaagaag aagctctttg tttagctgat aagatggttg
    20941 ttatgaatag aggagaaata atacaagttg gaacgccaaa ggaggtatat aaaaatccag
    21001 aaacaccttt tgtagctgat tttataggaa caataaattt tatagatgat ggtattaata
    21061 agatagctat tagaccagaa gatataaaag tagagtctaa tagagattct aaagataagg
    21121 atataaaagt gggagaaatt ttagatatcg aatttagagg atttaactat agaattacag
    21181 ttgagtatcg ttctaagcaa atgaaattag atgtagtttc caaagttgca gaacaaatga
    21241 aactgtgcat aggttctaaa ataaacttta agatacctaa agaaggaatt gtacaatata
    21301 aatcagaggg atgtgcttaa tagctagggg tgaataaatg ataacatcaa aaaataaaag
    21361 aagaataagt gatagcacaa tacaaaaata tttcttgatt ttttcggtaa ttgtactaat
    21421 agtatttata ttatttccat tagtatcatt attaaaaaat gcatttatgg atacaagtgg
    21481 aaattttata ggaatttcaa actttagtaa atatgttgaa aatccaagtc ttatagcatc
    21541 atttaaaaat tcaatttttg tatctacagt ctcatcttta atatcactat gtttagcatt
    21601 tatatattca tacgcaataa caagaacaaa cataaagttt aaagattttt ttaaaactat
    21661 gggaatgttt ccactttttg caccaactat gttatatggt atttcactta tatacctttt
    21721 tggaaataag ggaatcttta caaccatggg tctggaagta ccactatatg gtccattagg
    21781 aataattatt tctcagattc tatttacatt tccacaagct tttttaatat tatctgtagc
    21841 actttcgatg gctgattata gactttatga agcagcagat agcttgggtg ctagtgaatt
    21901 taagaaattt tgcaaaataa caattcctgg tataaagtac tcattactta gttcattctt
    21961 tgtatccttt atacttgcat ttacagattt tggagcagct aaggtagtcg gaggaaacta
    22021 caatgtactg gctactgaca tatataaaca agtagttgga caatttaaca taccaatggg
    22081 agctactgtt tctatggtaa tgttaattcc tgtactaata gcatttacat tagataagat
    22141 ggcaagtaag aaacaaggta tgaccataac tgcaaagtct atgccatata agattaagga
    22201 aaataagttt agagatagag tatttttaat agtatgtagt tttataacat tgctaatttt
    22261 tattttaata ttcgtttcag ttataggttc agttataaag ttatggccat ataatttaag
    22321 ctttacaatg gaacactata catttaaagg tattttggga agtggaataa aaacatactt
    22381 aagcagtttg aaaatatcaa ctttaacagc aatatttgga actatatttg tattttttag
    22441 tgcttatatg atagaaaagg tggataagtt tcctaaatta agacaaacag cttacctttt
    22501 atcaatgata ccaatggcct tacctggctt agttttaggt atatcatata taactttttt
    22561 taactcagca agtaatccat taaatttttt atatggaagt acagcaatat tagttatagt
    22621 aaatgtagtt catttttatt cagtttgttt tataacctca aattcatctt taaaaatgtt
    22681 ggataaagag tatgaattag ttgcaaaatc cataaatatt ccattctata aagtattttt
    22741 taatataaca gttccaatgt ctataacatc aatacttgaa atagtagtat attattttgt
    22801 aaattcaatg gttactgttt cagcattaat atttttatat acacctcaaa ctcagactgc
    22861 atcaatatca atactaaagt tagatgagat aggatatata ggaacatcag ctgctatggc
    22921 agtattagtg cttttaacaa atataatagt aagacttttg tacgaatttg taacaaagaa
    22981 attaaaaaat aacacacaaa aatggcagca aaaagatgtt gcatagggga ggtaaaaatg
    23041 aaatttaaga agctagtttc tttaggagta ttatcaacac ttttattaag tgtaataaca
    23101 ggatgtagta ctgattcatc aggttcagat tcaaagtctg atagtaagac aaaaggggat
    23161 ttaacagttt acacagcaat tgaagaagat agtatagagc catatttagc tacatttaaa
    23221 gagaaatatc cagatattaa attaaatatt gttagggcat caacaggaga tataacagca
    23281 agattattag cagaaaagga taatcctcaa gcagatgttg tatggggagt tgcagccaca
    23341 agcttattgg ttgcagatga ccaggggatg ttagaaccat atgctccaaa aggttctgaa
    23401 gaaatagagt ctgcatttaa agatgataaa gaagttcctt cttgggttgg gatagatgct
    23461 tggatgacag gtataacagt aaacactaaa gaattaagtg ataagaacat cccagttcct
    23521 agttcttacg aagatttaat aaagccagaa tataaaggtc ttatatctat gcctaatcca
    23581 tcttcttctg gtacagggta cttaacagta tcagccctta tacaaattat gggtgaagaa
    23641 aaagcatggc agtatatgga taaattgcat gagaatattg gtgtatacac tcaatctggt
    23701 tcagctccag ctacatcagc agcttcagga gaatatccta ttggtatatc ttttggatat
    23761 agaggtataa agttaaaaga ggaaggctat ccagtagaag tagtatttcc aaaagaaggt
    23821 tctggatggg atatagaagc aaatgctctt gtgaaaaaag ataatataaa agaagcatca
    23881 aaagtatttt tagattgggc tataagtaaa gatgtaatga acgaatactc taagaactat
    23941 gcagttacta ctatttctac aggaaatcca ataccagaag gattccctaa aaagccatta
    24001 gagcaaatga tagataatga tttaaaatca gcagcaaaaa atagagaaga tatactaaat
    24061 aaatggatat caaaatatga tggtaagaca gaaaaagaga gttaagtaaa actatacaaa
    24121 tggagtaaaa agaaagaatt tttttaagta gattttatta taataatata agttgagaat
    24181 aatataggtc aagaaaagtg aatattctat aaaaatgtat agagtaagta taccattcag
    24241 tttgaatggt atatttttta tttttagaga ttaatttaga aatagatata ctacagttta
    24301 aaatagtata ttttaatttc attattaaag tatagatatt atatataaag taaataaatt
    24361 attgagcgat tattaataag atatgtataa attttaattt gggaacttgt gttatatatc
    24421 atgaaaaaag agaaaaaata aaaggtaaat tgtttcttga taacttgaaa ttggaagtga
    24481 gaatatttaa ctagagaaga attatttaag tttaagtcag ctttaggagg aggaattata
    24541 aatgtctttt ttacaagtaa aaaatgtagg taaaagttat ggacaagtta aggtgctaaa
    24601 agacatatct attgatattg aaaaagggga gtttatttgc ttattaggtc caagtggttg
    24661 tggtaaaagt acattgctta gaataattgc aggacttgag gataaacatg atggaaaaat
    24721 aataataaat gataaggata tgactaactc accacctgaa agtagaaact ttggtattgt
    24781 tttccaatca tatgcactat ttccaaatat gaatgtatat aaaaatatag cctttggatt
    24841 agaaaataaa aatataagta aatctgatat agataagaag gttagagata ttttagaagt
    24901 tgtagaatta agtggatatg ataaaaaata tccatcacaa ttatcaggtg gacaacaaca
    24961 aagggttgca ctagctcgtg cgattgcttt agagccagac tttttgcttc ttgatgaacc
    25021 tttatctgca ttagatgcaa aagtaagact taaacttagg gaacagatta aaagtttaca
    25081 tagaaaacta ggcatcacaa ctataatggt aacacatgac caagaggaag ctctttgttt
    25141 agctgataaa atggttgtta tgaataatgg agaggtaata cagattggaa ctcctaaaga
    25201 agtctataaa agtccaaaaa caccttttgt agctgatttt ataggaacaa taaattttat
    25261 agatgatgat gtgaatatga tagcaattag accagaagat ataaaggtag aatttaatag
    25321 agactttaaa gaaattgatg taaaagtagg agagattttg gatatagaat ttagaggatt
    25381 caactataga attacagttg aatattgttc taagcaaata aagttggacg tagtttcaaa
    25441 ggtagtggaa caaatgaaac tatgtgtagg ttctaaaata aacttcaaga tacctaaaga
    25501 aagaaccata caatataaat cagagggatg tgcttaatag ctagaggtgg ataaatgata
    25561 acaataaaaa ataaaagaag aataagtgat agtaagatac aaaaatgttt tttagttttt
    25621 ttagtgattg cattagtagt atttatatta tttccattaa tatcactatt aaaaaatgca
    25681 tttatggata caagtggaag ttttgtagga atttcaaact ttagtaaata tattgaaaat
    25741 cccactctta tagcatcatt taaaaactca atttttgtat ctacaatttc atccttaata
    25801 tcattatgtt tagcgtttat atattcatat gcaataacaa gaacgaatat aaggtttaaa
    25861 aactttttta aaactatggg catatttccg cttttcgcac cagctatgct atatggtatt
    25921 tcacttatat acctttttgg aaacaaggga atctttacaa ttataggcat agaagtacca
    25981 ctatatggtc cattaggaat aattatttgt caaatactgt ttacatttcc acaggccttt
    26041 ttaatattat ctgtagcact ttcgatggct gattatagac tttatgaagc agcagatagc
    26101 ttaggggcta gtgaatttaa gaagttcttc aaaataacaa ttcctggtat aaagtattca
    26161 ttagttagtt cgttctttgt atcttttata cttgcattta cagattttgg agcagcaaag
    26221 atagttggag gaaactacaa tgtattggct actgacatat ataaacaagt ggtaggtcaa
    26281 tttaacatac caatgggagc tactgtctct atggtaatgt taattcctgt actaatagca
    26341 tttacagtag ataagatagc aagtaaaaag caagggatga ctataactgc aaagtctatg
    26401 ccatataaga ttaaggaaaa taagtttaga gatagagtat ttttaatagc atgtagtttt
    26461 ataactttat taatctttat tttgatattt gtttcagtta taggctcagt tataaaatta
    26521 tggccatatg atttaagctt tacaatggaa cactatacgt ttaaaggtat atcaggaaat
    26581 ggaatcaaaa catatttaag cagtttaaaa atatcaattt taacagcaat atttggaact
    26641 atatttgtat tttttagtgc ttatatgata gaaaaagtgg ataagtttcc tagactgaga
    26701 caaatatctt attttttatc aatgatacca atggcattac ctggtttggc tttaggtata
    26761 tcgtatataa cttttttcaa ttcagcaagt aatccattaa attttttata tggaagtaca
    26821 acaataatgg ttatagccaa tatagttcat ttttattcag tttgctttat aacttcaaat
    26881 tcatctttaa aaatgttgga tagagagtat gaattagttg caaaatctat aaatattcca
    26941 ttttataagg tgttttttta tgtaacactt ccaatgtcca taacatcaat acttgaagtg
    27001 gctgtatatt acttcgtaaa ttcaatggtt actgtttcag cattaatatt tttatatata
    27061 cctcaaactc aaactgcatc aatatcgata ctaaagttag aagagatagg gtatataggg
    27121 ccatcagctg ctatggcagt attagtgttt ttaacaaata taatagtaaa acttttgtat
    27181 gaattgacaa caaagaaatt aaaaactaag acacaaaaat ggcaacaaaa agaagttgca
    27241 tagaggaggt aaaaatgaaa tttaggaaat tagtctcttt aggaatatta tcaacacttt
    27301 tattgagtgt aataactgga tgtaataatg cttcatcagg ttcaaattta aagtctaata
    27361 ataagataaa aggagagtta acagtttata cagcaattga agaagatagt atagatacat
    27421 atttaactac atttaaagag aaatatccag atattaaatt gaatgtactt agattatcag
    27481 taggagatat aacagcaaga ttattagcag aaaaagataa tcctaaagca gatgtgttat
    27541 ggggggttgc agctacaagt ttgataattt tagatgacaa agaaatgcta gagccatacg
    27601 ctccgaaagg ctttgataag gtaaatcctg tatttaaaga tgataagaaa gttccttctt
    27661 gggttggaat agatgcttgg atgactggta taacagtaaa tactaaagaa ttaagtgata
    27721 agaacatacc agttcctagt tcttatgaag atttaataaa gccagaatat aaaggtctta
    27781 tatctatgcc taatccagct tcttctggaa caggatattt aacagtatca gaacttatac
    27841 aaattatggg tgaagaaaaa gcatggcagt atatggataa attgcataaa aatattggtg
    27901 tatacactca gtctggttca gcgccagcta tattagcagc ttcaggagaa tatcccattg
    27961 gtatatcttt tggaaataga ggtataaagt taaaaggtga aggttatcca gtagaagtag
    28021 tatttccaaa agaaggttct ggatgggaga tagaatcaaa tgcacttgtg aaaaaagata
    28081 atataaaaga agcatcaaaa gtatttttag attgggctat aagtaaagat gcaatgaatg
    28141 agtattctaa gaattttgca gttactacaa ttgacacggg aaatccggtg ccagaaggat
    28201 ttccaaagaa tccattagaa cagatgatag ataatgattt aaaatcagca gcaagaaata
    28261 gagaggctat actaaataaa tggatagaaa aatatgatgg aaagacagaa aaagagagct
    28321 aagccttgca ataaaattta gtacaaaaag cgcctagaat ataagtttta tatctaggct
    28381 cttttgatat atttatttaa aatgcatatt tctatataaa aataaatagt ttagtacctt
    28441 gattaaatta aataaaaacc ttaaaataaa gagatgtaaa gaaaaactaa aaacgaataa
    28501 aaggtgaatt tatatgataa aagaaataat agtagtagag ggtagagatg acgttacagc
    28561 agttaagaga gcaatagatg cagaacttat aactacaggt ggatttggat ttccaaaagg
    28621 tgtaatggag cgtataaaag ctgctaatga aagacgtggt gttataatat ttacagaccc
    28681 agattttgca ggtgaaaaaa taagaaaaaa aatagcatca gaagttccag gatgtaaaca
    28741 tgcatttcta ccgagagagg aagctaaaaa ggatggagat ataggtattg agaatgctac
    28801 tcctcaaagt ataatagcag ctctgaataa agttagaact gaaaatacag aaaaaagaga
    28861 tgaatttaag caagttgact taattagaaa tggtcttata ggtaatgaag aagcatcact
    28921 tagaagagat gcacttggaa aaatacttgg aattggatat ggaaatgcaa aacaattttt
    28981 aaatagattg aataattatg gagttgaaag agaagaattt atagatgcat taaaacaaat
    29041 ctaaacgtaa tgtttaatgt atgaaaaata tgtatataaa ataaattgtg gaattacggt
    29101 taatttaaga tgaattattt ataatataca ccttatttta aatcaatgta aatacatata
    29161 aataagtata attaataaaa ttaaatatca aaataagtta aaaaggagta aataatggat
    29221 agactatctt cacataatgc aacaaaggaa gtagtacaaa aatataattt taaattttca
    29281 aagtctttag gtcaaaattt cttgatagat agtaatataa ttgataaaat cttatctgga
    29341 gctagaatca caagaggaga taatatcata gaagtaggac ctggtatagg aactcttact
    29401 cgtgagatgg gtaaaatagc agaaaaagta gtggctatag aaatcgatag aaatttaatt
    29461 cctatattga aagatacctt gtcagattta gataatacag aggttgtaaa tcaagatata
    29521 ctaaaagtag acatacagga attagtaaaa gataaattaa atggtgggcc agttaagctt
    29581 gtagcaaatc ttccatatta tataactact ccaatagtta tgaaattttt agaggaagac
    29641 atacctgtaa cagacatagt agtcatggtt caaaaagaag ttgcagatag aatgaatgct
    29701 attccgggta ctaaagatta tggggcatta tctatagctg ttcaatacta ttgtgataca
    29761 gagattgtgg caaaagctcc aagacatatg tttataccac aaccaaatgt agattccaca
    29821 gttataggtc tacatgtaag agataaaaga aaatatgatg ttcataatga agacatattt
    29881 tttaaaacag taaaagcatc ctttggacaa agaagaaaaa ctcttcttaa ttcgttggga
    29941 ggtcttggtt ttcttaataa agatgaaata agagaagtat taaaagaagc taatatagac
    30001 gaaaaaagaa ggggtgaaac tcttagtata gaagagtttt cagttctttc aaatataata
    30061 aatacaaaag tatcttctaa atagaaggta ctttttttaa ttttgttaac atatattgtt
    30121 tagagaaact gtgttaaggg gggattgcag tgggttctaa aagaaagttt aaaagagact
    30181 atataatact agaagctaaa gacataaact ttagatacaa agaacgagta ctgccaaaag
    30241 cttttgcaaa agttgaagta aatgatgaaa aagcaattat tgcattatat gtagaaaatc
    30301 taaaatatgt taaagatggg tataaagcag tagcaataaa agatgaccat ggattaatag
    30361 acttaggaaa tataatttta aatgaacaag gaagaggtga atttgtttta gatttagaag
    30421 attatgatga tgagataaaa ggtattgcat tattgtatga aagaaatata cctttaattg
    30481 gatttaaagg aaataagctt gaaaattatg aggacatatt atttcaagag gtagaggaag
    30541 aagaatatga agaatatgaa gagttggaag aagaagacga agagatagag gataatgagg
    30601 aaagtgatag agacgaaggt agtgaagaag aatatattat agaagaatat gatgaagatg
    30661 agtatgaaga ctattgggaa gatgatgaag atattgacga aggagagtta aaagcaagaa
    30721 cggaagtaga agattctggt gatgaggaaa tagaagagtt caataattat aaggaaatag
    30781 aaaattataa tagggttaaa gtacaggaag aatatataga catagaatat gatgaggaag
    30841 aagaggaaga agaagaagtt tttgaagtaa atagagaaga agataggttt gtttcctcaa
    30901 aacctactaa atcaaagaaa gttcaaaaag atcagaataa tattgaaaaa ataaaaagag
    30961 ctaatggagt aagtcaagga gagagtggaa ataaacaaac cagtacatta cttatgccaa
    31021 gacaaataaa aaaaggtttg aaattattta aagaagtaaa accttttgta acagattata
    31081 tagataagac aagatggtgg aaaatagaga taaatcctac aacattgtgt ggatatacaa
    31141 tgccttattt aggatattta aacgtgttga attacaccat gtatagtgat gcagttttac
    31201 attcatataa atacagacac tatttatttg gagtccagta tgatgaatat aataagagaa
    31261 aacattatat ttatgctatc ccaggaaata gaaatgaaca gccagacaat ggaagcacag
    31321 gatttttaag atatcaagct tgtgataata gaacaaatag tttaggatat tggctatgtt
    31381 ttatagattc tagacaaaga aatatagtta ggtaaaaata ataaaaatga aaaaatttag
    31441 actcaattct tattttactg aaaaaattaa tgaaatgtag tacaaaactt taaaaactat
    31501 tgataatatt taaatattac actacaatat atcttgaaat acctattata ttatggagga
    31561 aaattatgat aaacgagcaa agaattttaa atgagtttct tgaattagta cagatagata
    31621 gtttatcttt aaaagagggg aatgttgcta aagtattagt taaaaaatta gaagaaatag
    31681 gttgttcagt agtaatagac aatgctggtg aaaaagcaaa tggagaaact ggtaatataa
    31741 tagctacatt aaaaggaaat aaagaaggaa agaaaatatt atttagttca catatggata
    31801 cagtaactcc aggtataggg gtaaaaccta tagtggatga agcaaatgga ataataaaaa
    31861 gtgatggtac tacaatatta ggttctgatg ataaagcagg tatagcagct atattagaag
    31921 gcttaagata tataaatgaa aataatatag aacatactga tatacaagtt gtattctcta
    31981 tatgtgagga atgtggatta gttggagcta aaaatttaga ctatggaaaa atagattctg
    32041 aatatgcatt tatattagat agtggtggtt ctccaggtga aataatagta aaagctcctg
    32101 cacaagatgt aataaatgtt aagatattag gaaagactgc tcatgcaggt cttgaacctg
    32161 aagctggaat aagtgctata atggtagctg ccagagcaat agaaaatatg aatttactta
    32221 gaatagacga agaaacaact gctaacatag gaattataaa cggtggaaca gctacaaata
    32281 tagtaacagg agaagttaat ataattgcag aagccagaag tctaaaagaa aataaattag
    32341 atgttcaaac taaacacatg gtagagactt ttgaaaaagc tgcaaaagat tttggagctc
    32401 aaattgagat agatgtcaat agagcatata caccaataga tgttagtgag gattctgaaa
    32461 taataaaact tgcaaagaag gctttttcaa acttaggtat agaaggtcat actgaatcta
    32521 caggaggagg tagtgataca aatatattaa gtaagaatgg tattgaagct ataactttag
    32581 gaattggtat gaaaaatgct catacactaa gtgaacatat agctataaaa gacttatatg
    32641 attctgctaa aatggtagtg gagataataa aggaagcata aatttaaata atagtgtata
    32701 atatatatat cgcctagctt aagctaggtg atttttcatt ttatagaaga ttgataatct
    32761 ctattgaaag taaagagtat acatttgcat ataagagagt gtttaattta tgttcaaatg
    32821 taggttctta ataatattta gattgtttca taagggagga ataaatatgg aaacaaggta
    32881 tgaagaagca aataaaataa caatacaatc aatactttgg aatgtagtat taacaataat
    32941 taaggttata gctggtgtta ttggtaattc tagcgctatg attgcggatg gattacattc
    33001 agcatcagat attataagtt ctataggagt actaataggc aattatgtat cttctagacc
    33061 tggagataga gagcataatt atggtcatga gaaagcagag acattagtat catttgtgtt
    33121 atcaatattg cttattttcg tttctataac aataggtata gaggcaatta aatctttatt
    33181 taacttagat gcattaagtg ttccatcaat attaccatta gtagtatcag ttatttcaat
    33241 cctgataaaa gagtatcaat atagaataac aataaaagtt gctaaaaaga taaattcacc
    33301 agccctaaaa gctgatgctt ggcatcatag gtcagatgct ttatcttcag tagctgcttt
    33361 tataggtata ggtggttcta ttttagggtt taaaccatta gacccaattg cgtcagttgt
    33421 agtggctata tttgtagcta aagtaggaat tagtatactt ataagttctg ttaatgaatt
    33481 gatggatgtt tcagttgatg aagaagagat aaaagaatta aaatttattg tagcagatac
    33541 agaaggtgtt aaaaatcttg gtgatataaa gactagaaaa catggagcta tggcatatgt
    33601 agatttgact atatgtgtgg atgaaaattt gacagttaag caaggtcatg atattgctac
    33661 caagcttgaa aaacatataa taaaacatat ggaatttgta aaaggcataa cagttcacgt
    33721 tgaaccatgt actaattgcc aaggaaataa gtgtaataat taattaaaac ttaaaaaaaa
    33781 gtgtaaaaag ttatataatt gttttatgat tataaactct aggggtggtt aaatgagcaa
    33841 gaaaagaaaa ctaaagaaaa aagctgcaat attaatagga gtagttgttt tctttataat
    33901 atactttata tcctttagaa taggaataaa tatggaaaag gataaaagtg aagtgccaaa
    33961 gaaggtagaa aaagaagaag aagataatag gtctttaagg actcaaataa aagagaagaa
    34021 gaaggtttat atatcagata aaaatataga aaacataaaa attgaagaag atatgtggga
    34081 tgaaataaag ttatttttct cagattttaa gaaagtaaga aatactactt cttcttacga
    34141 agcagtttat gaaggttatt ctgatgatgg agttaaattt tctactgacc ttaacttttt
    34201 tagagtatat actgtaaata aagaagaata ttataaagta ccagttagtt ctaaggatgc
    34261 ttttaagaaa cttttagatg agagcatata tacttcgttt gaccttttaa gtcattataa
    34321 agattggaaa gaggttacta taactcatgg aaaagaaatt aaaaaagttc atagatggaa
    34381 atttgatgat ttagcacata agatgatttc aaagagggtt gtaggaaaag ttcaacctga
    34441 gaaaagtaag gaaagaagtg actataattt tactataaat ataaaaggtg ataattttga
    34501 tgtaaaagtt gatacaatgg gaaaagatta tgtaaaagtt acttctaaga aaaatgtatc
    34561 ttactatgag gttcatacaa gtttatttga ttaccttaaa aatgagatat ttgaaattgg
    34621 aaagaaataa gactttaaga aggctatcaa attagatatt tgatagccta aattatttta
    34681 tatattattt ttcaaccaac aagtctgcaa ccttataaat tggaccagca ccagcagtta
    34741 ttactaaatc attatcctta acattttcac gtaagtattt tactatatct tcaaattctt
    34801 ttatatagat ggcatctaca ttgttttgat ataatttctc aaccaagtcc ttagaatgta
    34861 tatctcctgg gtctttttcc ctagcagcat atatatctgt tatgataact ttatcagcag
    34921 catagaatgc ctctgaaaat tcacctaaaa gagattttgt tctagtataa gtatgtggct
    34981 ggaagataca ccataaagtt gattttttta attttttggc agcagctaaa gttgctttta
    35041 actcagttgg atgatgtgca taatcatcta ctactaaagc attcttataa taccctttag
    35101 tttcaaatct tcttccgaca cctttataaa tttttatatt ttttcttata gtctctaagt
    35161 caataccaga aacaagagct gccattatgg cagaagaagc attgtatatg ttatgaagac
    35221 catatacaga aagttcaaat tctcctaaat ctcttccttc atattctatt ctaaatattc
    35281 catgaccact attgtcaaag tgaatatctt ttattacagc atcattgtca gaatctctgc
    35341 cgtattttat aatagtagct ttaacatcat acaatatgtc atcaatattt tcatcatcgc
    35401 catttattat gaaatagcct tctgggggta ataattttcc aaatttgtta aaagaagctt
    35461 tgatttcatc tattccagag aaataatcaa gatggtcttc ttcaacattt aaaactatag
    35521 atatctttgg gttaaaatta aggaaactat ctacatattc acatgcttca gttataaagt
    35581 ggttggaatt acctatctta acattaccac ctatcatact taagttacca ccaactagta
    35641 tagttgggtc taagtctgca tattcaaaga ttgtagataa catagatgtt gtagaagttt
    35701 ttccatgtgt tccagaaact gctatagaat ttttatattc cctcatgatt tggcctaaaa
    35761 aagtcgctct gttcattacc aatttatttt tttctttagc agccacaagt tcttcattgt
    35821 ctggatgaac tgctgctgta taaacaacca tatttacatc atctgatata ttatcttttt
    35881 tctgaccaat ataaatagtt gccccttggt ccctaagttt gtctaatagg tatgattcgt
    35941 ttgaatccga acctgaaact tgataacctt tattgataca tatttcagct aatgcactca
    36001 tgctgatacc gccaattcct ataaagtgta tattcataat aaaaccacct ttctttttaa
    36061 ttaagtccta caatatgaac tatttctgtg gtataataat ataatgttca atattttata
    36121 attaatatgc atataatatt atatgtattt tatttttgaa tataataaaa cataagtaat
    36181 attataccac aataagaatt gttatgcatt agttagttta acgttatata aaggtacttg
    36241 taggaggaaa taataatgaa atttaaaaga acagagagaa ttggagcaat agttaaaata
    36301 ctgtctgata atccaaataa aatatatact ttaagttatt ttacaaatca atttaatgca
    36361 gcaaaatcaa caataagtga agatttatta gttgtaaaaa atgtatttga gaagctacat
    36421 ttaggtaaag ttataactat ttcaggagca gcaggaggag taaaatatat acctaaaact
    36481 tctatagcag aaaatgcaga gttcttaatg gaattatgcg agagaatatg tgacaagtct
    36541 agaatactat ctggtggttt tttatacttg attgacctaa tttacgaccc tacaatagct
    36601 gctaagatag gaaagatatt cgcatcaaat attgagtatg tagatgcaga ttatgttgtg
    36661 acaatggaaa caaaaggtat acctatggca cttatgactg caaaagctat gaatttacct
    36721 ctagttataa taagaaaaga tataaaggta tcagaaggtc ctacacttag catgacatat
    36781 gtgagtggaa acagttctaa agttgaaagt atgagtttgc caagaaaagc tcttaaacca
    36841 gatagtaaag ttataattat agatgatttc atgaggggtg gaggtactat aaaaggaatg
    36901 gtagacctta tgaatgaatt tggtgcagag gttataggta ctggagtatt catatctaca
    36961 acgaatcctt cagaaaaaat ggtaaaagat tatatttcgt tgattcaatt ggatgttaat
    37021 ggagataaaa tagtagtaga accaaactta aagactttta aagatgaata tagaaatgaa
    37081 gatttagacg aagaagaaga ttcagaattt gaatttgaga tagatgaaga ttaataaaaa
    37141 aaatatttag aaaaatatgt aaaaataaaa agaggatatc cctagttgtt catagaatta
    37201 tttaaaaaac agtttatatt aatttattcc agcgataata attttaatat aaattaattt
    37261 ctgtcaaaat caaaggggga tattttggta tgaagataac tgacgtaaga gtaagaaaat
    37321 taacagaaga aggtaagatg aaatgtatag tttcaataac tttcgataat ttgtttgtag
    37381 tgcatgatat aaaagttata gaaggccata atgggctatt tatagcaatg cctagcagaa
    37441 aagtaggcga aggaaatttc agagatatag ctcatccaat aaatgcagaa atgagacaag
    37501 ttttagaaga tgcagtttta caagcgtatc atgaagcatt agttcaatgg gaagtagctg
    37561 ctgaataata ataaatatat aaaatggaga gagcccgaac atttaggctc tttttaaatg
    37621 tagaatttct attaaaatat gtacttttta gtaaaaaagt gctatattat tagtgataat
    37681 gtatatgttg tatacaaatt gttagataaa tgtattataa tgtatattga ttaagagaat
    37741 aatacgaata aaattaaatt agattgaatg gagtgtatca atgaacttta aagctataat
    37801 ccttgctgct ggcaaaggaa caagaatgaa gtctaaatac ccaaaagtta tacataaagt
    37861 atgtggaaaa gaaatggtta accatattat agatgtttca aaaaaatcag gggtaaaaga
    37921 tactgtcgtg attttaggac atgaagctga tgtagttaaa gaaaagcttg cagaagaaat
    37981 tataatagcc atgcaaacag aacaacttgg gacaggacat gctgtaaaga tggctaaaga
    38041 atatattaat gatgaagata caatagttgt actttgtgga gatactccac ttataaaaga
    38101 agagacacta aagagactat ttgaatatca tatagaaaat aaatatcatg ctacagttct
    38161 tacaacaaga gttggaaatc caacaggtta tggtagaata ataagagata agaagggtga
    38221 ccttcttaaa atagtggaac aaaaagatgc aaattcagaa gaaaagatga taagtgagat
    38281 aaactctgga atttattgtt ttaatggaaa gagtcttaga gaagcactag atttgctaaa
    38341 taataacaat tcacaaggtg aatattattt aactgatact gctaaaataa tgagagataa
    38401 aggattaaaa gttggtgcat ttgcaggttc aactattgaa gaacttatgg gcgttaactc
    38461 aagagtagaa ttatcaaagg cagaagaaat tatgagacga agaataaatg aatctcatat
    38521 ggtaaatgga gtaactataa tagacactaa ctctacctat atagaatctg atgttatgat
    38581 aggcaatgat actataatat atccaggtgt tatgttacaa ggaaaaacaa ggataggttc
    38641 agattgtata attggaatga attcatctat aacaaattca gaaataggtg atggtacaga
    38701 aataaaaaat tcaactataa ttgatagtaa ggttggagaa aattctactg ttgggccata
    38761 tgcatactta agaccaaaga gtgacttagg aaataatgta aaaataggcg attttgtaga
    38821 agtaaaaaat gctattatag aagatggctc aaaagcatct cacctttctt atataggaga
    38881 tgcacatgtc ggtaaaaatg taaatattgg atgtggagta gtatttgtaa actatgatgg
    38941 taaaaataaa tttaaatcaa tagtaaaaga caatgcgttt ataggttcaa attctaattt
    39001 agttgcacca gtagttgtag aagaaaaagg atatatagca acaggttcaa caataacaca
    39061 tgatgtccca gatggtgctt tggcaatagc aagagaaaga caagttatca aagaaggatg
    39121 ggtagaaaaa aagaatcaaa aagacgacca aagtaagtaa ttatgtagtt tattattttg
    39181 gctaaaaaat ttagctcgaa attattataa attatattca ttagtatttt aaaattttca
    39241 ggagggttac ataaatgaat actagcggaa gcgagattaa aattattgca ggtaattcat
    39301 cgaaagagtt agcacaaaaa atagctgact atataggtgt atcagtacta gattgtgaag
    39361 taggtacatt tagtgatggt gaaatatgtg taaacatgaa tgagacagta agaggttgtg
    39421 atgtgtttgt agtgcaatct actaacagcc cagtaaatga taacttaatg gagttattaa
    39481 tcttaattga tgcgttaaag agagcatcag caggtagaat aacagcagtt attccttact
    39541 atggatatgc aagacaagac agaaaggcta aggcaagaga tccaatcact gctaaattag
    39601 ttgcaaattt aataactgct gctggagcag atagagtatt aacaatggat ttacatgcag
    39661 ctcaaataca aggatatttt gatataccat tagaccactt actaggtgga acaatattag
    39721 caaattattt taatgaaaag aaaatagaag atttagtagt agtatctcct gacttaggaa
    39781 gtgttactag atcaagaaaa tttgctaata ctttaaatgg agaagttcca atagctataa
    39841 tagataaaag aagaccgaaa gctaatgtat gcgaagttat gaacttaata ggtgatgtta
    39901 aaggtaaaaa tgttatacta ttagacgata tgatagatac agcaggaaca atagttaatg
    39961 ctgcaaatgc acttaaagag tttggagcaa aagatgttta tgcttgttgt actcatggtg
    40021 tgttatcagg tccagctatt gaaagaattg ctaattcaga aataagtgag ttaatagttc
    40081 ttgatactat acaacttcct gaagagaaaa gaatagataa gataaagata aaaacagtag
    40141 ctcctttatt tggagatgct ataagaatga tattctctaa tgaatcagta agtaaattat
    40201 tctaatttat tgtatttatg agagttgttt aaaaggatat aaaccttttg agcaactctt
    40261 ttttgatttt ataattatgg aatgttattt ttttcttgtt agaaaggtat atattattgt
    40321 aaaaagagat tatagtttaa aattatgtat atttaagtaa aataaactta ataaagggca
    40381 tattattcaa aatattatga atataaaaaa tattacaaaa aagtattgaa aaaattcaga
    40441 ttatgtagta ttatgtaaat ataaataaag aaagaaagag gtgtttccaa tgggaaggtt
    40501 agaagatgaa cccctaataa ttaaatgatt cagtcacaat ctaaagtgaa tataaaaatc
    40561 tattgaaagt ttatttataa gaattgaaaa tagtatctat tctatcttta gtgtttgtga
    40621 gagggttctg gattatataa gattactgta aagaagtaat tttgcacaat aagcatatct
    40681 gtaaatgaag agtttcgttt atataatgat tgtggctgaa tcataactat aatagataga
    40741 atgtttataa tagatgattt tataaaatac tatattgtaa tagcttttag ctttcaaata
    40801 aatattagca aaggatggaa atgacaatga taaaactaaa tgataattta taaatatctc
    40861 cttacgatat ataataattg tagggagatg tttctttttt ttgtagagta taatttttct
    40921 agaaattctg tttcaatatg taaaaagttg gtatatataa atagtataaa cagtgttgct
    40981 aaaatatggt agatattata taatataaat ggatatgtat atacattatg agttatataa
    41041 tttgaattta ataaaataga aacgttgatt tatgttctgt aatgtgggca ccttggagca
    41101 tattgagtta gtggtgcaac cggctatgaa attgtattta tttataaata ctattatttt
    41161 catagctttt tttatttaaa aaatggttat atgttagaaa taaatttggt tagtacgttt
    41221 aaataatttt acttagattt ttaaccagat atattataag taagtattaa ttaaaaaatt
    41281 taagggggaa taaaaatgaa gttaaaaaag aataaaaaag gtttcacttt agtggaatta
    41341 ttggtagtaa ttgcaattat aggtatatta gcagtagtgg cagttccagc tttatttagt
    41401 aatataaaca aggctaaggt agcaagtgtt gagtctgatt atagctcagt taagagtgca
    41461 gcattatctt attattcaga tactaataag ataccagtta caacaactga taaagctggt
    41521 ttaactattt tagagactta tatggagtct ttgcctgata aagctgatat aggtggaaaa
    41581 tataaattga ttaaagttgg taataaattg gtattacaga taggtacaga tactgaagga
    41641 gttacattaa cagaagcaca atcagcaaaa ttattgagtg atataggtaa agataaaata
    41701 tatacaggtg ttacaggaga taattttgga gacgaattaa cagatactac aaaaatagat
    41761 aataaagctc tatatatagt acttatagat aatactgtga tggactcaac aaaataatta
    41821 aaactatatt tttataaaga atattgtaaa tttaatgaaa aatataatat aaaagacagg
    41881 aagaaaatct tcctgttttt ttatactatt ttctttaatg ttcaattatg aatgatgata
    41941 taattgagat agtaaaggag tgaaacctgt ggctaaaaaa gttagaatag gagacaaact
    42001 ggtcgaaaaa ggatatataa cagaagaaca gcttaaatgg gcactatcag aacaaaaaaa
    42061 cagtggaaaa agactaggag aatttctagt acaagaaggg cttatagata gtaacttact
    42121 aataagtgta ttaaaagaac tcttggatat agaaagtata tttttagaag ggacagaaat
    42181 agacacttta gctacaaaaa tggttccaga aaatatatgc aaaagatata ctgtatttcc
    42241 atttaaaatt gatggaaata aaatatgtct agccatgtca gacccacaag atagagaagc
    42301 agttcaagat gtaaggcgta tgtctggtaa agacgtagag atatttatat caagtacaga
    42361 agatataaac aaagcaatag gtcatgctta tgcacattca gaaataaata aggcaatgac
    42421 tgagtacaac aaaaatagaa ctggtggagt aagagaaaca gtaatacttg aagaagatgt
    42481 aaatgctgct ccaatagtac gattagtaaa taacatacta gaaaatgctg ttagaatgga
    42541 agcaagtgat atacatatag aacaaagtga aaattacatg cgtgttaggt ttaggataga
    42601 tggaatgtta agagaatata tgaggatgaa ctcagcacca tataaggcag taatcagccg
    42661 tatcaagata atgtcagata taaatatatc tgaaaagaga ataccacagg atggtagaat
    42721 ctatttaaaa gtggataata aacccataga ttttagggtt tctacaatgc caactaacag
    42781 ggatgaaaag atagctatga gggttcttga taagagtaat tttatggtta gtaaagaagt
    42841 actaggaata gacgaacatg gctctaagat atatgatgaa ttgataaaca ctccttatgg
    42901 tcttatattg gttgttggcc ctactggaag tgggaaaacc actacattgt attcaatgtt
    42961 aaatcaacta aatacagaaa atagaaatct attaacaata gaagacccta tagagtatga
    43021 attacctggt gtaaatcaat ctcaaataaa tgaaaaggca gggcttactt tcgccagcgg
    43081 acttagagct tttatgcgtc aagacccaga tataataatg gttggagaga taagagatac
    43141 tgagacagca gaaatagcaa ttagagcttc tcttacagga catttagttt taagtacatt
    43201 acatgcaaat acagcagttg gagcaatttc acgtctttta gatatggatg tggaaagttt
    43261 tttaataact tcatctgttt taggtgtaat atctcaaaga cttacacgaa aaatatgtga
    43321 gcattgtaag gtttcatatg aagcagatat tggagaaaaa aaggctcttg gtattgatgt
    43381 aaatgaatca gtaactattt atagaggaaa aggttgtgaa aggtgtaata atactggata
    43441 taaaggacgt ctaggtatat ttgaaatgct tgaaattact ccagaaataa aagagttaat
    43501 agattcatct gcaaatcaaa gagaaatttt aaagatggct agaaaacaag gtatggttag
    43561 cttaaaagag gatatagtta aaaaagtttt aaatggaaag acaacagtag aagaaatgat
    43621 tagaataatt ttgatgactg attaaaggat gatattatga aaagttttaa atacacagta
    43681 ataaaagagg acggaaaaaa gcaaactgat gtgattgaag ccaacgattt taatgaagct
    43741 agaaatcttc ttagaaagag aaatcttaga gttattgaaa tcaaagaaag caaaaataaa
    43801 aatataagat tatctagtag aaagagaaaa aaagacttag gagctgacca gataagccac
    43861 ttttgtagac aatttgctat tatagtatct tctggtataa atagtatttc tggattagaa
    43921 acattagcta gaaggtcaac taacattaca ttaagagaag aaattaatcg tatagtagca
    43981 gaaataaaag taggttctac tattgcagat tcaatgcttt catcaaaatc aaagtttcca
    44041 aagttacttg gtgctatggt agctacaggt gaagctacag gtaaattaga tgaagtatta
    44101 aaaagtatgg cttcatttta tgcaagtgaa cacagggtta aacaaaagct tagaaatgct
    44161 gcaacatatc cattaatagt tttgatttct tcatttataa tgatttttat atttacaaca
    44221 tttatggtgc ctaagatgat taattcaatt acaacagtag gagcaactct tccacttata
    44281 acaagaattg ttatggggtt tggtatgttt atgaagaagt tttggataat agtactttta
    44341 gttattatat tatttatcta tcagtttaaa aaatatctaa aaacgtcagt tggaagggct
    44401 cataaagata gagttataaa taagatacct gttttaggaa aaggaataaa ttgtatggta
    44461 gctacacgat tttcaagagc attgtatcta tttgtatcaa caggataccc attagttcaa
    44521 gggcttgatt atattataga tagtgtaaat aacactatgg cagagaagat tttagcatca
    44581 gctaaagatg gaataacaag aggagaaggc ttagcagaaa atttagagag atatacgtat
    44641 tttgactctg tgttggtaca gatgatagct ataggggagc agacagggga attagagaat
    44701 ataagtagac agatggcaga attttatgag tatgaatccg agatttattt aaataggatg
    44761 gcctcaatga tagagcctgt tttaataatt gcagttggta ttatagttgc gatactggtt
    44821 gtatcaatat tcatgccaat gcttagtata tatgatgcca tgtaggaggg aaaggacaaa
    44881 tgaacaaggt ttatgtatca tattatggcg attctatttc catagttgag ggcagatata
    44941 aacacgataa ggataagttt tatgtaaaaa attttaatgt gttttcaata gaggatattg
    45001 cacaagattt ttctaaggaa aagtatgctc tattgagata cgcattagaa aatgttaagt
    45061 taaaatcaag acatgtagtt ttttgtttaa atacaagaga tgtaatttta aaaccccaaa
    45121 aacttcctaa tatggacaaa aaggatttag acggatttat gaagctagag atggacgaaa
    45181 tgatggcttt ggagtcagat gaatatgtat tttcgtatga agtatctagt gaaacacctg
    45241 ataattcaga tggcgatgaa tcaagcttaa atcttattat tggagctata caaaaggaag
    45301 aggtaaatgc aattgtagag ataatgcatg aatttgattt agtattagat agaatagata
    45361 cattatcaac agcttactta agaatgctta aaaatttaga ctacaatgat ataatggtaa
    45421 ccaatataag tgacaatagc acaattataa atatatataa gaaagatact ttatttatta
    45481 gtgataatat acctataaag ataactgcta aagatatgga catgcaatta ttaaatgtag
    45541 tagaagaatc aaaaggtctt atgaattact attcgtcaag aaactttggt aaggttacgg
    45601 atactatatt aatattagga aaaagatatt ccaataaatt aatttatgaa acttttagct
    45661 ctgcattttc aagctatgtt tctcaaggcc ttactgagat aatggatata tctgatatga
    45721 taactggaga tatagatgaa gatgatataa attcaattgt agagctttta ggaagtatga
    45781 tagaacctaa agggaaaaga gattttgaaa atataaactt tttaccaatg gatatactta
    45841 gaaaacagat aaaagctaaa caaatgaaaa acatactgaa aattgctcca atagttattt
    45901 tgattcttgc tataccttat ttatgtttaa ttttttcaaa taatttagca aataaggaac
    45961 ttgaaaatgt taatggtgaa ataagaaata ttgaatctgc atattatcag attggaaata
    46021 tagaaaaaat gatacagagt aaaagcgaag aaataaaggt atatgatatg ttaattggga
    46081 aaaaggtaaa gtgggaaaat ttattggatg atatagataa aaatactcca agtaaagttg
    46141 aactaacaag tttatcaaca acttatcaaa atcttggaac taataataaa gctgataatt
    46201 caaaaagtaa taagactaca acagataaat caagtaacaa tgaaacaaaa tcaagtacga
    46261 aaagtgatag taatggagat aaaacagata atgatttaaa tgaagataag actacaaatg
    46321 tgtcagaagc attaactgga aatagtgaga ctaatagtaa taacacggat aaagatgata
    46381 aaactccatt gtatgataag ataccaaatg ttataaatat agaaggaaat gctaaagatt
    46441 cctcttatgt aggtcaattt ttatataaat taaagggatt atactatttc aaggatgtta
    46501 aattacatag cataaaaagt aatgcagaag attctaacta tacatttagt atgacattat
    46561 acctgaaaga aggtgtatta actaatgaat aaagatatat ttaaaaaaga tataaaagat
    46621 atatttaaaa tggaagttag tctaaaaggg attcttataa aggttataat tttattagct
    46681 attttatcat atggttattt tggactttac cctcaatatc agaaatatat tgctacaaaa
    46741 aattctgtaa aacaggctac tgaaaaatta aatatatata aagagaaaac tgcacttatg
    46801 ccaaaatatg aaaaacaact tgaggaagtt gaaagtgaat taaaagaaaa aagcaaaaat
    46861 cttttatatg atatgcaaga tggtcttttt ttaataggtt tagataaaaa aatgaaggct
    46921 tataatattg acttaaccag ttatgacgtt ggaaatgtta aagaatacga acatttttat
    46981 ggtatatcaa caacaataag tgttagaggt gattatagaa atgtcaaaaa attaatggct
    47041 tatttagaag aacaaaaaaa tgttactcaa atactagatt atacaatgac ttcatatata
    47101 gaaccagaaa aagaagagga agaaacaaca aacaataagg atttaattaa aaatgtgaac
    47161 ataaataaag atacaaaaat atactgggtg gaaggcgaaa ataagtggca tttatataag
    47221 gattgtccat tgataaaaga gggagagatt ataaaaaatg acaaactttt agataggtct
    47281 actaattatc tatgtaatac ttgtgtactt agagctgcaa cagaaaaaga agcaaaaaaa
    47341 gaagtcgtag ctccaaaggc agaaggtgta gtagatgcta catttaaatt tataatgtac
    47401 actaaagaga atactacaat gatacttgat acagataatc catcttcatg gagaccagga
    47461 aaatataatc catttaagtc tagtgcgaaa taaagctaag taagctttaa agataggtga
    47521 tgagtttgta caaaaataat gaaaaaggtc ttactttatt agaagtaata atagctgttt
    47581 ttatactgac aatagtttta agtatttctt ataaagtgtt caatggtata acatcagcag
    47641 taaaaaagca acagattatt acagatgctc aagtaaatat taatctaatt aataagtatc
    47701 taaatagaga tttggaaaac tgtaaagagc taactaaaac tggttcaggt aataattatg
    47761 aatacaatat agagatgcca gataatgttg taaaatatga agtttctata gaaactaaaa
    47821 aaaatacaga ggtatattct gtaacgagaa tccaaaacaa tacaattgat acagaaaatg
    47881 aagttagaga agagataatc tataatcaac cactagttca aaataataaa gaaatgaagg
    47941 aaacaccatt taaaatagaa aagcaaactg gtaaatctat ttatactgta agtatatact
    48001 ataatgaatc ggtgcaagaa agtcataaaa atagcaattt aaataacaaa acttatacat
    48061 ttgatgttat gtcaagaata gggtaataag aatttattaa aaaataagta ggttgataaa
    48121 atatgagtaa aaagaatagt gaaagaggat tttccttaat tgaagtgtta gtagctatgg
    48181 ctattatggg aattgtacta tttgcatttt ttaatattat caatactaat aacaaagcaa
    48241 acactaaaaa tgacacagat ataacttcct taaactatgt ccaaagtgaa atagaaaatc
    48301 taagagaaaa gataaaaagt ggagaatttg attttgatag tttagataaa ctagaagatg
    48361 gaactgtcgt atatgaaaaa ttaatagata aatcaaaaaa agttgtatat gataaagttc
    48421 ttagtgaagg tgatgtgagc ttatatgata ctccatatga aaagattaca acaataaaag
    48481 atgaagatgg taatttaatc gacaaaggaa atattacaaa taagataaag actattgtag
    48541 aagataaaag tggtcagata tataaaatag ctgtaactgg gaaaagcatg aatgactatt
    48601 caagtaaaaa agaggttaaa attgtaactg aaatatttaa agataaataa ttttacttgg
    48661 gggtgagatt ttgaggaagt ggaataaatt taaaagtgaa agaggggcag ctttagtttt
    48721 agttttggtt gtagtagcat tgctttctat tgttggattg atattttcaa atcagatagc
    48781 taatagaata aaatctacaa agactactaa tgaaggtata caagcaaagt atttagcaga
    48841 gacatgtgtg gaaaatagta ttgataaagc atatgaaaaa ttgtatgatg agcttgagaa
    48901 aatggataat gagtttaaaa gtgaaaatca agaaaaatcc atatctaggt caaaattaag
    48961 aaatatatca gatgaagatt ttaataatca agatgaggaa aatattgaag cagaaagact
    49021 tggatatatg aataatataa atttctattt aaataaagct tcttcagact tggaaaaagc
    49081 tagtatggaa ttgaaaaagc tatatgattt agatatgttg gactatagag acattgaata
    49141 tgtagatgca aatattattt cacatagaaa ttctatctta gaaatttgca agaattatac
    49201 ttctggagat attagtaaaa taaatgaata tattctgaaa gaagatatag actcaactac
    49261 attgattgag gcaaagttag tgaataatga tattctttta aaaaagtttt tagaagaaaa
    49321 taaaattgaa aatgaacatt taaattcagc cttttcacat acttataagg cattagataa
    49381 catttctttg gcgatgcaaa atatgattga gtatagacat acgtttcata tagatgagcc
    49441 aaaagtagaa gtatctaatg ggattccaga ctctcaacaa tattatgaac taatacaaaa
    49501 tcctataata aatagtatgg agtatagctg gaatagtaaa tgggatacat tagaaaacct
    49561 attggaaatt ttaccaaatc aaactcaagg atttaattct ttaagagttc atttgagaaa
    49621 taatgtaaga aaatttgaga agttaagcga taatatatct agtggtaaaa aaaatacagc
    49681 aaaaaatttc ttaaagtata aagagttatt gtatgaaata tcagaccaat gtaatcaact
    49741 aaaaagtatg tcttatgaga aaatacctgt taaatatgat aacatggctt tgataacaac
    49801 ttttgactat atacaaaatg agcttttagc agagataaaa tgcagattaa aagaattaaa
    49861 accacaagaa attgataaaa cagaaggtat tactataaaa ataccttttt ataaggctga
    49921 ctacgacatg acaaaagaag gatggcctaa attaaaagaa aatggttcag gggcggagtt
    49981 aagcttaatg gtaactggtg ataaaaatgg aataaaagaa gtagaagtta cagatggtaa
    50041 aaaaaatatt attggtttag gtgttgaaga aaattcaaat tcaaagtata aggttgacgc
    50101 cattgtaaac tttaatctaa atatagatac aaatgtagtt ggaaattatg atataaaaga
    50161 taaaattttg attaatcatg atataagttc atacaaaaaa gtaaactaaa tataagaagc
    50221 aacttagtat aaataaataa taaaataatt ttattattta ctactaaaaa aataagtaaa
    50281 ctaatagaag atatggagag taaatattat gtatatttat gatttattag agcaaggtat
    50341 aagactaaac gcatcagata tacacataac agttggaaca aatcctgtag ctagagtaaa
    50401 aggtggattt gtaaaactaa gtgaacaaat attgacatca gaagtaacaa tgcaaatggc
    50461 aaaagacata gcaggggaat ctatgtttaa agtaatagaa gaacatggag aagctgattt
    50521 ttcagcttct ctaaaaacag gagaaagatt tagggtaaat gcatataggc aaaaaggaaa
    50581 ttacgcaata gcaataagga ctataacagc agaaattcca acatttgaaa aattaggcct
    50641 tccagagagt ataaaatctt ttactgaaaa gcataaagga ttagttttag ttacaggtcc
    50701 aacaggaagt ggtaaaagta caacacttgc aagtatgata aatataataa atgaaaaaca
    50761 acaaaaacat ataattacac ttgaagaccc gatagaatat gtacatcatc ataaacaaag
    50821 tttagtaaat caaagagaag taggaactga tacagaaagt tttcattcag cccttagagc
    50881 tattttgcgt caggacccag atgtaatact aataggagag atgagagacc ctgaaactgt
    50941 ttcaatagca ttaacagcag cagaaacagg tcatttagta ttttcaacac tacatacagt
    51001 aggggcagct aagacaattg atagaatagt agacatgttt caaccatccc aacagcaaca
    51061 aataaaaaca cagttatcta cagtttgtga aggtgtggta tcacagcagt tacttcctac
    51121 agcagatggg aaaggcagaa tagcagcaat tgaattgatg tttgctactc cagcaataaa
    51181 aaacctgata agagaaggca aaacatatca aattccaaac atgatacaaa ctggagttaa
    51241 agtaggtatg aaaactatgg accaagattt aatggaactt tataaaaatg gaaagattac
    51301 aaaagatatg gcacttagta ggtgtactga ccaagagttt atgacaagaa tgataggtgg
    51361 agtaaactac aatggatatt ataatcgtta atctatatgt atttatagtg ggtatagtgt
    51421 ttggaagttt ctttaacgtc tgtattttta ggattccaga aggtatatct atttctagac
    51481 caccttctca ttgtatgagt tgtaatacta gactaaagcc aatagactta ataccagtgc
    51541 taagctattt aatgagtggc agaaagtgta gatattgtta tgagaaaatt tctagtagat
    51601 atgctatagt ggaattaatt acaggacttt tatttttaac agtatttatg ttatatggaa
    51661 tatctacatc aactatttat tatttggttc ttgtgtcttt actgattata attacattta
    51721 tagatattga ccactttata ataccagata aaatattggt ttttggagct atattttcta
    51781 tgatttttaa ccttttattt aaagaaattc cagttaagga ttcaattcta ggtgttttta
    51841 tttgtggagg aagtgtctgg attatagttc ttttgattga atttgtaata aaaaaagagt
    51901 gtatgggtgg aggagatatc aaactatttg caatgctagg tttttacatg ggtgttaaaa
    51961 atggtctttt gacagcctta ctaagcgttt atgtgggagc agtctatgga atctgtgtaa
    52021 taattataag tagaataaaa ggaaaggaat ataattctgt tataccatat ggacctttta
    52081 tatctattgg agcattaata acaatcttat ctggaaagca attacttgaa ctttattttt
    52141 ctatggttat atagatgata gtcaagttaa ataaagtttt aatttaaaaa aatgaattaa
    52201 agtatttaat aaggacaata ttattattaa ccctattact aaagtgctac aaactatgga
    52261 gtatataata ataatttcct tattttttgc acatttgata aataaatctc tatgtgtttt
    52321 ttgtgataga gaaaagaaaa atttatataa tacgtttttt atttacataa taactgtagt
    52381 tttatctgta ttaatatatc taaaatttgg gattagtgta gaatgtgtac aatatatggt
    52441 tttaattcca tttttaataa ttatatccat tgtagattac tacacaatat atgtatatga
    52501 tataacaata gttagtggta taatagttca aggtataatt tttttggcct ttttcaatat
    52561 agttcaattt gattatataa atcatatatt tggactattg ataggcttta ttatacctta
    52621 tattattgct aaactaacaa aaggattagg ctatggagat gtaggtctct atagcttatg
    52681 ttgctttgca ttgggaaata attatgggtt ttatgtgata gttttatcat ttattttagc
    52741 gtttttgttt tttattattt tatacataac taaaatattt aaagatgtag atataagaaa
    52801 gcaaattcct tttacacctt ttatttcctt gtcaacaatt ttaataatat ttacagagta
    52861 taatatattt aatttttatt ataatttgtt atacaaattt atataacagg aggtaagaaa
    52921 tgtacgtagt agtagggtta ggtaatccag gaaagaagta tgagaagact agacataacg
    52981 ttggatttga tgttatagat attcttgcta aagaatacaa tattagtgtt actaaaataa
    53041 agcataaagc tttgattggt gaagggagag taggtactga aaaagtatta ttagttaaac
    53101 cacaaactta tatgaattta agtggagaaa cattaataga tatatataaa tattataagg
    53161 ttgatttaag taatatagta gtagtatatg atgatataga tttagaagtt ggaaagatac
    53221 gtataagaaa aaaaggaagt ggaggaactc ataatggcat gaaatctata actaagtgcc
    53281 taggttcaaa tgactttcca agagtgagag taggtgtatc taaaccagaa gctggtcaag
    53341 acttagcaga ctttgtactt tctagattta gaaaagaaga atctgataac ataaatgaag
    53401 cattagaaaa agcggcagat gctattgact caataataag agaaaatata gatatgtcta
    53461 tgaacaaata taatggatag tgagagggag atttaaatga atgatgtttt tttatatcct
    53521 ttgcaaaatt caaaagagta taaagatata ataaactgta taaaaaatac aaaaggctca
    53581 ttattggtta atggactttt accagtacaa aaacctcata tatcgtattc tatatttaat
    53641 gatttatcac gacaaatgat ttttataacg agtagtgatt tagaagcaaa gaaagtatac
    53701 gaagatttaa gtttttatat ggaagataaa gttgaatatt taggttttca agatatttat
    53761 ttttatcact tggatgcaaa ggacagaaac gaagaagcga agaaattaaa agtattgtta
    53821 aaactagcaa ataaagaaaa aatcatttta gtaacttcta ttgaggcagt tttaagaaaa
    53881 tacataccaa aacaagtttt gctcgatagt gtatctcatt ataaggtggg agatagctta
    53941 gacttagaaa agttaactga gaaattagtt tcattgggat atgaaagagt ttcaaaaata
    54001 gaggggtttg gtcaatttag tataagaggt ggaattattg atgtattttc acttgaatat
    54061 acaaatccaa ttcgtatgga attatttgat gatgagatag attccatacg aacttttgac
    54121 gtatattcac aaaaatcaat tgataaattg caacaattct ctataactcc atctagggaa
    54181 tttatttatc ccgaaaaaac tacagatgca ttagttaaat taaaaaaaga aacaactaaa
    54241 aatactgatg aaggtacatt tcaaaatata gattatatat caagtaagac ttattttgaa
    54301 ggtgtagaga actatataga ttatatttat ccagaagaaa acaaaagtat atttacttat
    54361 ttagcagatg atgcaatagt atttattaat gatataacga gacttaaaga aagatgcgaa
    54421 aattatataa atgagtttag agaaaattat aaattaaatc ttgaaagagg tctggctatt
    54481 aaaaaccaag gtaaattgtt atatcactat acagatttag agtacttagt aaaagacaag
    54541 tctgtggtat taaactcgct attgccaaag tctataaata acttttctat aaaatctata
    54601 ataaattttg aaagtagaga agttcctaca tttaatggaa aggtagattt gcttgtagaa
    54661 gaattaaatc ggctgaaata taatggatac aaaataattt tagcaacaaa taccttagaa
    54721 agagcaaata aattaggaaa agatttattg gacaaaggct tagaaacgac catttctaaa
    54781 gatagagata ttgaaattaa atcttcacaa gttataattg tacctgcaca cataaacagt
    54841 ggttttcagt ataaatctat aaagtttgtt gttataacag ataacgaaat gataggtgtt
    54901 tataaaagag cgtctaagac tagcaataaa aaagttaaaa agggaaagaa aatagaatcc
    54961 tttttagatt taagtgttgg agactatgta gtccatgaaa atagtggtgt aggtagatac
    55021 acaggaattg aacaaattac agtcaatgct attaaaaaag attatatgaa aatagtatat
    55081 caaggtggag ataatctata tgtgccaata gaccagatgg acaaagtaca aaaatatatt
    55141 ggtgcagaag tagaaaaagt taagttaaat aagcttggaa caaatgagtg gacgaaagca
    55201 aaagcaaaag ttaaaaaaga aattgaagat atgacaaaag acttgattga gctttatgca
    55261 aaacgtgaaa aaatacaagg gtataagttt tcaaaagata caccttggca ggcagagttt
    55321 gaatcgttgt ttccatatca agaaacagaa gaccaattaa aggctataga agaaactaaa
    55381 aaagatatgg aatcaagtaa ggtaatggat aggctagtat gtggagatgt tggttatgga
    55441 aaaacagagg tagctattag aagtattttt aaagcttgta tggaccaaaa acaagttgct
    55501 gtattggttc caacaacaat attggcccaa caacattata atacattcaa agagaggttt
    55561 gaaaattatc ctttgagagt agaagtttta agtaggttta aaacaccaaa acaacaaaaa
    55621 cagattattg aagatgctaa aaaaggatta gtagatattt taattggaac acatagaata
    55681 atatccaaag atataaattt accaaactta ggtcttgtag tcattgatga agaacaaaga
    55741 tttggagtaa aacataaaga agctttaaag aaaattaaat ctacagtaga tgtacttaca
    55801 ctttcagcaa ctcctatacc aagaacatta catatgtctt taagtggaat aagagacatg
    55861 agtgttatag aggaacctcc acaagaaaga catcctgtaa taacatatgt tacagagagt
    55921 aaggaaagcg taattcaaga tgagatagag agagaattaa gtagaggtgg acaggtattt
    55981 tttgtataca atagagttga acacattgaa gaaatggcaa gtatgattca aaaactcgta
    56041 ccagatgcta gagtggctgt tgcacatgga agaatgactt ctaaatcatt agaaaatata
    56101 atcctaggat ttttaaataa agattatgat gtactagtct gtactacaat aattgaaact
    56161 ggtatggaca tatcaaatgc aaatacaatg attatatatg atgcagataa aatgggattg
    56221 gctcaacttt accaattgag aggtagggtt ggaagaagtt caagacaagg atatgcatat
    56281 cttttgtatg aaaaagataa aactttaagt gagatagcgg agaagagatt aaaagctatc
    56341 agagaattta cagagtttgg ttctggtttt aaaatagcaa tgagagacct tgaaataaga
    56401 ggagcaggaa atattttagg ttctcaacaa catggtcata tggcagttat aggttatgat
    56461 ttgtacgtta aaatgcttaa tgatgcaatt aaaaaagtca aaggtgaacc tattgtggag
    56521 gaaattgatg ttgaaataga tttaagtgta aatgcataca ttccagataa ttatatcaaa
    56581 gatgagttga ttaaaattga aatgtataag aaaatagctt ctattgaaaa caaagaagac
    56641 atgttggata tacaagaaga acttgaggat agattctctg atatacctaa accagtccag
    56701 acacttctta caatagctta tataaaatcg ttatgtaaga tattaaaaat agaaaagata
    56761 agacaattaa aagatgaaat attattagtt ccaataacaa agtatagaac taaacagaaa
    56821 ataggttata atatagttac agaattagaa gaattattag aaaagatgtg caaggtaaaa
    56881 taacttgtaa atttaagaag ggatgtttta aatttgaaaa aggtaataac attggtaata
    56941 gctatgattt tggtagtatc tgtgactgct tgcagttcta gtaaaggaga aactgtggca
    57001 acagttgaag gtacaaagat atcatcagat gaatttaaaa aaactatagc tctttataaa
    57061 gattctatgg aacaaactta tggaaaagat atatgggata aggaagttga aaagggtgta
    57121 aaatacaagg acaagtttaa agatttaatt cttgaccaac ttataactac agaagtaata
    57181 tattctcaag ctaaaaaaga taacttactt cctaaaaaag aggatgttga aaaaagcttt
    57241 aaagaattaa aagacgctat gggtaaagat gaaaaatata aagaacaact taagaaatta
    57301 ggtatagatg atgagttttt aagagaccaa caagagaaag atttagcaat gcaaaactat
    57361 caaagtaact ttgctaaaaa gactaaaata tcagatgaag aaatgaaaaa atactatgat
    57421 acacataaag atgaatttaa aaaagatgag gtagaagctt ctcatatttt attgaaaaca
    57481 gtagatgata ataacaagcc actttcagat aaggaaaaag ctgaagctaa gaaaaaggct
    57541 gaagaggctc ttaaagaagt taaatcaggt gaggattttg caaaagtagc aaaaaaatat
    57601 tcacaagata cttcagcaag tgatggtggt aaattaggat tcttttcaag gggtcaaatg
    57661 gttgctgaat ttgaagatgc tgctttttct atgaaaaagg gtgaagtatc tgatttagtt
    57721 gaaactcaat atggatacca cataattaaa gtgacagaca gaataaatga gcaaacatca
    57781 tttgaagatg ctaaagaaac tataaaagac caactgttga aaaataaata tcaagaacaa
    57841 atagaaaaat taactaaaga agctaaggta gaaaaagatg aaaaagtaat aaataaaatc
    57901 acaatctaag acttaaaaaa agagtaatat gcttaaaaaa gctatatctg gataagatat
    57961 agcttttttt gtatattttt cttaacaatg gtaaaaataa acttaaagta atttatggag
    58021 ggattaaaaa atatgaaagc aacaggtata gttagaagaa tagatgatct tggaagggta
    58081 gttatcccaa aagagataag aaagacatta agaattagag aaggagaccc tttagagata
    58141 ttcacagcaa aagatggaga agtcatactt aaaaaatact ctccaatagg tgaattaaat
    58201 gaattttcgc aagaatatgc tgaaacatta gctgaagtac taggatatgg agtgttgata
    58261 acagacttag attctataat agctgtgtct aagcttccta aaaaagatta taaagaaaaa
    58321 agtataagtg atgagttaga agcaataata agtgaaagaa cagtaaaata ttcaaaagat
    58381 aaaaacattt taccattatt caaggaagac caaaaagaat atactagtca agttatcatg
    58441 cctataatta gtgcatctgg tgactgtata ggttcaattg tagttgtttc aaaggataaa
    58501 gatacaattg cagaaagtga agaaaaatct ttaaaaattg ctgctaactt tttaggaaaa
    58561 caagttcaat aattttatca taaagacctt ttacatgaag gtcttttgaa gtttttgtgt
    58621 aaaatattga atatagcatt aaaaatatgg tatattaaag tttgttatat aaacagtatg
    58681 gaggttatgt tatgaacaat aacaaaaata aagactcctt tctaaaagga gcccttatac
    58741 ttgggctagc aggtgtaatc gtaaaaataa tgggtggatt ttttaggatt ccccttggaa
    58801 acatgattgg ttcagaagga atgggatact atcaggctgc ttatcctgtg tatactctat
    58861 ttttaacatt agctactgct ggatttccaa cagctgtggc aaaattggtt tcggaaaaag
    58921 ttgcaattgg aaattttaaa ggtgcaaata agatatttaa ggtatcacat acagttttat
    58981 tcattaccgg tataatatca ttttgtatat tattttttgg agccgactac atagtaacaa
    59041 acgtaatgaa aaatccaggt gcgttatact ctatgaaagc cattgctcca gcattactat
    59101 ttgttcctgc aatgtctgca tatagaggat attttcaagg gagacaagat atgactaaga
    59161 ttgctgtgtc tcaagttgca gagcaatttt ttagagttgt attaggtctt actttggctt
    59221 acttgcttat gaagagtcta ggtcagactt ttggtgcagc aggtgctata tcaggggcta
    59281 caataggttc aatagcatct atgctttatt tggtgtttgc ttatatgcta gggagaaaag
    59341 agcgtagagc agagatagat gcaagccaaa gatttaaaga tgaaagagtg tcttatattt
    59401 ttaaaaagct tttaactgtt gccattccta taacaatagg agcatcagta atgccacttg
    59461 taaatatgat agataatgtt attgtaataa gaagacttat ggaagcaggc tttacataca
    59521 aagtggcaaa ttccatgttt ggtcaattaa caggtatggc aatggccaca ataaatttac
    59581 cagcagtcat aacaactgca atgagtatga gcttagttcc agcaatttct aaagcatatg
    59641 cattaggaaa taagtcaaaa gctagaaaag atactaagag tgcagttaag gtaactttac
    59701 ttatagtatt gccttgtgcg tttggtatgg cttctttagc aataccaata atgggtcttt
    59761 tatttccaca tgaaccatct tctgtaggaa ctattttgtt tactcttact ccatgtgtat
    59821 tatttttagg attaatacag acattgactg gtataattca gggaatggga aaaccaatag
    59881 tacctgtaat tgctttatgt gttggtatgc tatgtaaaat tgtaataagt tatactttaa
    59941 caggtatacc agatattaat gtactgggtt cagcatttgg tacagttaca gcatactttg
    60001 tggcagccat gattaactta ctatatgtta aaaaacacat gaatgtaaac ttttctaaaa
    60061 aagaatttat aataaagcca tttataacag ttatgacaat gtttataatg gttaagttga
    60121 gttatggtgc tttagttgga ttcttaggaa acagcatatc tacaataatt gcaatatgtg
    60181 ttggtggaat tgtatatgta gtagtaatac ttggaatagg tggaattaaa aaagaagaga
    60241 ttctaactat gccaaaaggt gataaattat ataaattgtt aaaaaaagtt aaacttataa
    60301 gataatatag gaatatatat gcaaataaag gaaatactat acaaatagta aatctcctta
    60361 tttgtataat aatataaaaa taaagtgaaa tttgctaata ggagtgatgt tatgggtaag
    60421 ataagtattg taggtcttgg accaggagac tattctctta taagccaagg tgtgttagaa
    60481 tctttaataa atagccctaa agtttttttt agaacagaga aacatccaat aattgataaa
    60541 cttaaagaaa ctatacaata cacttcttta gactactttt atgaaaaaga ggaaaatttt
    60601 gataatgttt atttgaaaat atctgaattt atcatagaag aatcagcaaa gggtgaccta
    60661 gtgtatgctg ttcctggtca tccaagagtt gcagagaaga ctgtaagtat aatagagaga
    60721 ttagccaatg aaaagcacat agcagtagaa atattgcctt ctatgagctt tgtagacgct
    60781 atgtttaact atttggctat agacccatct gagggattta aactggtaga tgcttttgaa
    60841 atagaaaatt catatataga cttggataca agtatgataa taactcaggt atatgataaa
    60901 tttatagcat ctaatgtaaa gttaaaactt atggaacatt atgactataa tcaagaagta
    60961 tgtatagtaa atggagctgg tgtcaaagat ttagaaagta aaaagtttat aaagctttgt
    61021 gaattagaca gaaatgaaaa cttttttgac tatttaacta gcttatatat acccaaaagt
    61081 tctaaaaaga tgtataatac agtacatgac ttagaaataa tagttaatac acttagaagt
    61141 ccatctggat gtgaatggga taaaaaacaa acacatcaat cattaaaaaa ttctgttata
    61201 gaggaagcat atgaactttg taatgcaatt gataataatg atatagatga aatggtagaa
    61261 gagttaggtg atgttctttt acaggttata ttccattgtc agataggaaa tgaggagggc
    61321 tactttgatt taaaagaagt agtaaatggc atatgtaaaa aattaattca tagacatcct
    61381 catatattta gtggtgcaaa attagatatg tctaagtttg agaaaacttg ggaagaatta
    61441 aagaaagaag agaaaggcga aagtactata acagatggcc ttagaaggat accaaaacat
    61501 ttaccagctc ttatgaaggc tagtaaagtt caacataaag cagcacttgt cggctttgat
    61561 tgggacaatg tagaagatgt atttaaaaaa attgaagaag aatatcagga attacttgac
    61621 gaacacaggg tcgggaatat aaaatacata aaggaagagc taggcgattt attattttcg
    61681 atagtaaatc tagctagatt tttagacata gactcaggag aagccttgaa ctgtactaca
    61741 gaaaaattca taaatagatt tgactttata gaaaaaagtg caatgaactt gaataaaaaa
    61801 ttagaagaca tgacacttga agagatggat gagttttgga atcaggctaa aaaacaataa
    61861 aattgtggaa ggaaatttgt caaaaatcta gaacttttat cacaaagata gaagtctata
    61921 ttataaacat ttttaggagg taaatatcgt gaataaagct gaattagtat caaagatggc
    61981 agaaaaaagt ggattaacaa agaaggaagc agaagctgcg ttaaacgcat ttatgagttc
    62041 tgttcaagat gcactagtaa ataatgaaaa agttcaatta gttggatttg gaacatttga
    62101 gacaagagaa agagctgcta gacaaggaag aaatccaaga gatccagagc aagttataga
    62161 tataccagct tctaaagcac cagttttcaa agctggaaaa ggattaaagg atataataaa
    62221 tggataatta gaaatcttgt gaaaaagtgt ggataaattt gccacacttt ttctatagaa
    62281 ccaaggaagg tgataattat gagattagat aaatttttaa aagtatctag gattataaaa
    62341 agaagaactg ttgctaaaga tgcatgtgat aaagggattg tcactataaa tggaaaagtt
    62401 gctaaatctt cttcagaggt gaatattgga gatacattag aaatacaatt tggagagaag
    62461 aagatgaagt ttaagataaa tgaagtaaaa gagcatgtat taaaaaatga tgcaaaagaa
    62521 atgtacaaaa ttttagaata aaattaatag tcctctagta tattaatagt agtattattg
    62581 aaatatttac tggggggata ttatggaaca gaacataact ttgaaagata gatcaaagct
    62641 ggttatttcg ggagtcgagc acatatactc ttttaatgac aaaagagtag agctcaaaac
    62701 ttctgtaggc gagatggtaa ttgaaggcga aaacctagat atgagcaagc taagtataga
    62761 cgaaaatata attagcatag atggaactat aaattctatg gtatatgcaa agcctaaaaa
    62821 gccacaagag agtttcttga aaaaggtatt tagatagatg atacctttta ctcaagatgt
    62881 aagcattttt tatgctacta tttatggtgg aatactcata ggggtgttgt ttgattttta
    62941 tagagggcta agagggaatt ttaaattcat caattatttt gctataatct ttgatgtatt
    63001 gttttggttt ctagctacgg ttataatatt cgtaacaata aaccttacag aattttttga
    63061 tttaagatat tatcattttg tggctttgtt tattggtttt attttatact ataacaccat
    63121 aagtaaaatt gttttatcaa ttatcaataa aataattcgt tttgtgagaa attcttttaa
    63181 aaaagttaca cattacatag tcagtttttt aaataatttg tattacgtta taatctattc
    63241 actacaccta ctatttgata ttatatttta tataccaaac atatttatag caacaagaaa
    63301 aagtataaaa agaaaatcaa ataaaaaatt aaagaacaag aaaaaatcaa aacctaagaa
    63361 gaaaaaaaat aaaactaaaa aaagggtgta ggaaaaatga acttaagaaa aaaattttca
    63421 ggacagatta ttgttatcag tttattttta ggaatatcaa tttttagtat gatgacagga
    63481 tttgtatttg agtatacaaa agctaaggaa tataaaaaag aaatagcaag tctaaataaa
    63541 caattaaaaa agactgaaat acaaataaac agcttaaaga aagatgaaaa atcatatgaa
    63601 ggagacttag aggatatagc aagaaaaaga ttgaatatgg taaaaccaaa tgaaacagtt
    63661 tatgtagaca taaatcgttg attaaaactt gctaataagt ttacagatgt attgatttta
    63721 aaatttaaga tttaataaaa aagtcattca gttaaggatg gctttttgtt tttattgagg
    63781 agggaatttc ataatgaaag taggagctat agatattggg acaaactcaa tgagattatt
    63841 gatagcagat tatagagatg ggaattttat aaacagaaaa aaatttgtta atacaactag
    63901 aattggttat ggtgtggata gtaaaggata tataaaagaa gatgctatca aaagaaatat
    63961 aaaagcatta aaagaatttt ctgataagtg taatgatgaa aagtgtgaaa aaatttattg
    64021 tatggggaca tctgctctta gagacagtaa aaatggagat tactttgtta aattagctaa
    64081 agaagaaact ggaatagatg ttgatatagt tacgggaata gaagaatcaa atttgggctt
    64141 taagggtgtt ttagaaggaa tacaaggtga tgatactatt attgttatag atattggagg
    64201 aggttcaaca gaatttattg taggtgattc agaaggaatt aaatttaata aaagtgagaa
    64261 tgtaggtgct cttaggatga cagagaggtt tttgaagcac gatattattg aagatgaaga
    64321 gtttgaagct atgagttcat ttatatatga tgagattgac aaaacgttaa atcatataaa
    64381 agacagagga ttaaaaactc ttataggtat aggaggtacg attacatcat tatcagcaat
    64441 gaatcaagaa ttagagattt actctatgga aaaaatacat aatagtaaaa tacacaaaaa
    64501 agaaatagaa gaaattctac aaaaattaat aaagatgaca ttaagtgata aaaagaactt
    64561 aaaagggcta caagaaaaac gtgcggatat tataactgct ggtgtaaaaa tattgaatat
    64621 aataatggaa aaattagaaa tagaagaaat aaccgtaagt gaatacgata atttggaagg
    64681 cttaatatgt caaaagtcaa aaaaaatgta ttaatatttt ttgattttta aaaccgatta
    64741 tgacaaaaaa aattactcct ctttgttaca attcttaata taaacaaaag aggaggtttt
    64801 tttatgcaaa gaagtgtagc agttgtgaag aataagactg taaaaccaaa tgtcataaaa
    64861 ttaataagcg gatatattga ttttactacg gcggcattcg ctgtgatggg atttttactt
    64921 agtaggtcta ttatagtaga ctctgtagct cctttaggaa ttgccttttt tatatgtgca
    64981 tcaaagattg ataagtacaa gatacctgta ttcatatcaa cattattagg aatattgtta
    65041 tcatctaatg attttggaaa tgtagcaaaa tatgctgtgt gccttacaat atttatggct
    65101 atgaataaaa aattaaaatt atcagattca attgctaagg ttgcatttat aggtgcaata
    65161 atactacttc caatctccat gggacaagct ttcttttcaa ataggtatgt atatggtctt
    65221 cttatagcag gagtagaagc aataataatg tttatatcta tatatgtgtt ttcttatggg
    65281 ataggtttaa tggccaatgt caacaatagg atgtctgtac ggacagaaga agccatatca
    65341 ataagtttac tgctaacctt tagcataatg ggaataggag atatatctct gtttggaata
    65401 tcaataagga ccattttatc gaccgtattg atattgctga cctcaatagt aggtggagct
    65461 accatgggag catctagtgg tgtaattatt ggtgtagcat ccattttaaa taatatgaca
    65521 tcagctgttt atatggggat atattctttt tcaggattaa taagtggagc atttaataaa
    65581 ataaataaat atttctgtat actaggatat attctaagtt ggacaataat atacctatat
    65641 acttctggta ttacttctaa tatgatgcaa ttaagagata tactattagg ttgtttgata
    65701 gtactagtat tgccagagag attatttaat aagattgaaa aattaataaa aagtaatgtg
    65761 gcttcaaatg aaatcgtata cgattatatt atgagaagca aaaacctaac taatagcaga
    65821 ttgaacagta tttataaaac ttatgatgac cttgcagata catttgataa gataagagaa
    65881 aaagacaaag tgctagacca aagagacata gctaatgtaa tagatatgat tcataatgat
    65941 gaatgtaaaa gttgtagtat gagaagaatg tgctgggagt caagatttaa tcatacatac
    66001 actatgatat ataacattct tgaaaaaatt gaggagaaag gggagttaag tctaaacgat
    66061 atacctaaaa attttagaaa ggaatgtatg aaaccagagt caatagtgaa aatatcaaat
    66121 cactattaca aaatgtttgt attagattat gattggagtg tgaagttttc agaaagtaga
    66181 aagttaatag caaatcagat aagaagtatt tcaaaatcca ttaaatcctt atctcaagat
    66241 ttagaaggcg acataatgct agatatagaa aaggaaaaaa atatatatga acagttagaa
    66301 agatatgata taacagttga taaagtaagt tacttaacaa aaagtaacag tgagtttgaa
    66361 atatcaatag aaaagaaaac ttgccatgat ggatgtatgt gtgaagataa aattgtaaat
    66421 ataatttcag acctagtagg ggaaaatatg tctgttagaa aaataggatg tcactgttta
    66481 ggaggtaaat gcaaggcaac attcgttaaa tctcaaaaat ataaggctgt tacagaagtt
    66541 tcagcaatgt caagggatgg gcatatcctt tgtggagaca attacacata catggagata
    66601 aatgatggta aatacatgat ggctataagt gatggtatgg gaaagggtaa aaaagcatat
    66661 gaagaatctt ctgccactat tgatatactg gaaaaaatga tagatgcaaa aattaaagat
    66721 gagatagtca ttgatactat aaacaatatg ttgttgttaa aatcttcaga agagatgttt
    66781 tcaactctgg atttgggaat tttagattta aaacgaggtt gtttagaaac tataaagatg
    66841 ggagcgtgtt ctacttatat aaaaagagag gatggagaag ttgacttaat atcatcatca
    66901 tcattacctg tgggtatatt atcagatgta aaaattgata gaaaaaatgt aaaagttaag
    66961 gaaggagact atgttataat ggtttctgat ggaattgtag atgcaggaag aaataacaat
    67021 ttaggagaca attggttaat atacttctta aagaatatag agactacaaa tccaaaggaa
    67081 atttcaaatt taatattgga tagagcatta gagttacaag cgttacaaat cgaagatgac
    67141 atgactgttt tagttacgaa aatatgtaca aaataaggtt tacaagatta tgtgtataag
    67201 atgtggataa cttgtgtata atatgttaat agacttttga aaaaagtata gttattaaca
    67261 aaaataacat ataaatcaac aaaatttgtt gataagtatg gcagaaatgt taataaaatg
    67321 taaaaaaaga aaaaacaaaa gctattatca aaagagattc atgttgaaat aactaaattt
    67381 ctaagtaaag aaaacctgtg aatatgttga ttattatgtg gataactatt aattcgatat
    67441 ttatttatat agtatgaata attgaataat atatctaaaa aaagccatcc tattattaag
    67501 taaacttatt gaaaggatgg ctttttatga atagaaaatt gtgcaaagca ataatacctt
    67561 tatttatttc tattttttgc atgttaataa taagtataaa agctgaccaa ggatatcaaa
    67621 agaataatga cagagcaatt actgtcatga ataataatga tactgaagat gatgctgaaa
    67681 aaaaacaaga aatagactat gaaaaaacat gttggaattt gcaatctttg tttaaaagtg
    67741 atgaccaatg gaaaaaagaa cttaagagtt ttgataaaga tactaaagag ttgaaaaatt
    67801 acataggtaa agtaacaaaa tcgccaacac atttgtcttt tgccttgaac attaaagaaa
    67861 aacttgatat aagactaaat aaactttctg cctatgtaaa attaaaacaa gatactaata
    67921 aaaattcgta taagtactta gatatgaatg atagtatgag taaatcctat gggaattata
    67981 tggggatttg ttcagattta gagttagaaa tactaaaatt atcaaacaaa gattacaaga
    68041 aaattatttc aaataaaaat ataaatagga aatatggtgc atatttaaga gatataagaa
    68101 ggaataaagt acattatttg gatgataaat cagaagatat tctaagcaaa gtatcttcaa
    68161 taagtagtct tccaagtcaa gtgtatgaat tatttagaaa tatggataga aaaactaatt
    68221 taacaccagc tcaatatgcg agtgaattag agtcatcaga tagagaaaat agaaaaaaag
    68281 cttatcaaga tgaacttata acttacaatg ataatataaa tacaattgca ggtttaatta
    68341 ctggtcaagt taaaaagaat attttttatt ctcaggaaag aggttatgag tcttctttag
    68401 aaatgtacct ggaagctgat aatgtagatg aaaaagtata caataatttg ataaggactg
    68461 taaatagtaa tatggacagt ctacacaaat atatagattt aagaaaaaaa gtattaaaat
    68521 tagataaggt tcattcatat gatatgtttg tgcctatggt taaggctgtt gataataata
    68581 ttaattatga aaaggcacaa agtatagtat attcagcgtt gtcaccttta ggaaaagaat
    68641 acaatgatgt agtatataaa gctttcaatg aaaaatggat agatgtttat tcacatgaaa
    68701 ataaagtaag tggtggatac tgcttatctg tttatgaaaa tcatccatat atacttttaa
    68761 attataataa ttcattaggt tcagtttcga ctttatcaca tgagcttgga catgctgtat
    68821 atgaatactt aagttctaag aatcagaatt attttaattc aaatccgtct atatttactc
    68881 acgaagttgc atctacaacg aatgaagcat tactttacga gatgcttata aaagaagcta
    68941 aaggcaatga tgaaaaagct tattatataa cacagtattt agacttgata aaagatactc
    69001 tttatacaca aactatgtat gctgaatttg aaaaaactat acacgagtta gtagaaaaag
    69061 gaaaaagtgt aaacgcatta gtattaaatg atgtttgggg acaacttctt aaaaaatatt
    69121 atggacaaag ctatgaatta gaccaattat ctaaggtcgg atgggctaga atcccacatt
    69181 tttataatag tttctatgtc tataaatatg ctacaggttg tagtgcagga gtaagttttg
    69241 cccaagacat cctaaagaat ggttcagata actatatgag ctttcttaaa aagggaagtt
    69301 cagattatcc aataaacttg ttaaaatcaa gtggcataaa tttaactaat acaaaaccca
    69361 tagaaaatac aatcaaaaaa tttgatagtt tagtagcaga acttgaaaag ctattataaa
    69421 cattattgta atccacatgg taaatatatc gaattaatga taaaatatac taaaagttta
    69481 aagtcctatc aagataggac tttttattta ttaattagtg ggagatgatt ctatgcaagt
    69541 taaagttaaa aaggctgtaa taccagcagc aggtttagga actagatttt tgccagctac
    69601 aaaggcacaa ccaaaagaga tgttaccaat agttgataag ccaactctac aatacataat
    69661 agaagaagct gtggcctcag gaatagagga aatactaata ataacaggta gaaataaaaa
    69721 atctattgag gaccactttg ataaatctgt agaattggaa cttgatttag agaaaaaagg
    69781 taagaaagaa ttgttggagg tagtacaaaa catatctaac atgattaaca tacattatat
    69841 aagacaaaaa gagccaaaag ggttgggaga tgcaatttat tgtgcgaggc attttatagg
    69901 tgatgagccg tttgcagtaa tgttagggga tgatattgta gataatgatg taccttgtct
    69961 aaaacaacta acagatgcat atgaggaata tagaactaca atattgggtg ttcaaaaggt
    70021 aaatcaagaa gatactaata aatatgggat aatagaagca aaaaatatag aaggtagagt
    70081 ttacaaggta aaagacatgg tagaaaagcc agagtcagga aaagctcctt caaatattgc
    70141 tattttaggt agatatataa taactcctga aatctttgat attcttaagg atttaccacc
    70201 aggtaaaggt ggagaggtac aacttacaga tgctttaaaa atattatcta agaaagaagc
    70261 tatgtatgca tacaattttg aaggcaagag atatgatgtt ggggacaagc taggattttt
    70321 agaagctact gttgactttg ctctaaagaa agaagacctt aaggaagatt ttataaaata
    70381 tttgaaacat gtatgtagtg aatttgataa aaataacaat gtgttataca ataatacaga
    70441 tgaaaaaata gatttaattg aagtcaatga agctagagaa cttgaaattc aaaaataatt
    70501 aatgaaaggt gatgtatggt ggcaaaatca agtcagaaaa gaattaatag aataatagct
    70561 gttgggattg tgggaatcct cgtaataacg agtataacag ctgttttgag tatgattgca
    70621 actatgtaat aagataaatg acagcagttg atatacataa atataaaaac catatataac
    70681 ttgatgtagt caaaaactta caatatttta gttatatatg gtttttagaa tttataaatg
    70741 taaaaaaaaa tttttataat agttgcatat tttaaaggaa aatattatta taagatataa
    70801 atatagtgat aaatttataa aaacgtgcta agattggact tgaaatacag taatatagta
    70861 ggtaataatg ttttaaattt tatttattga ccataatata taaataatga tattattaga
    70921 cttaactgtt taaataaaac ttttcttttt catgccttca atttccaaaa taagtatgta
    70981 tataaatgaa tatatagatg aggaggattt ttttgatttt agatgataaa gtattagaag
    71041 gattaggtag taagacctta gttgagctac gagagatagc taaagaatta aaaataaaat
    71101 caattactac atataagaaa aatgagttaa ttgagattat aaattccaaa agtaaaaatg
    71161 aggaaaaagt aaacgaagag actaaagaaa aaaatgaaga tattaaagaa gacataaaga
    71221 atagaaaaga aaatatagag cgtgaaagta tagaaaaaga agttgaatat aagagcccta
    71281 ccaaatcata caacaagaaa gaaatagata cccaaaatat ttcccaaaac caagaacata
    71341 gaaatcaaag aaatgactat aataagacaa cgagtgtaaa tgatagtaat aagtcatcaa
    71401 atatatctaa tagaatggtc agaaataata ataaaaacta ttatatgcct aaacaagttg
    71461 atgaatctaa gatagtagat gaatttaaca catcaaaaga ggatgaagta gtaggtgtac
    71521 ttgaaattct gccagatgga tttggttttt taagaggttc aaattatttg tctactgaag
    71581 gagatgttta cgtttcacca tctcaaataa gaagatttaa tatgaaaaca ggagacaaga
    71641 ttaagggaat aactagacat ccaaaaagtg gagagaaatt tagagcactt ttatatgttc
    71701 aaaaaataaa tgatgaaaac cctgacacag ctatacaaag aaatgcgttt gagacattaa
    71761 caccaatatt tccagaagaa cgacttacac tggaaactaa tagaaatgaa atagctacaa
    71821 gaattataga tttaatttca cctataggaa aaggacaaag aggattgata gtagcacctc
    71881 caaaagctgg gaaaacagtt cttttaaaaa gcgttgcaaa tagcatagct aaaaatcatc
    71941 caaatgttga acttatagta ctccttatag atgaaagacc agaggaagtt actgatatga
    72001 aagaatctat tgaaggagac gttatatatt ctacttttga ccaagtatca agtcatcatg
    72061 tcaaggttgc agagatggtg ttaaatagag ctcaaagatt agttgaacat ggtaaagatg
    72121 tagtaatttt actagatagt ataactagat tggcaagggc atataatctt acaatatctc
    72181 ctacaggtag aactttatct ggaggtattg accctggtgc acttcatgga cctaaaaagt
    72241 tctttggtgc agcaaggaat attagacagg gtggttcttt gacaatatta ggaacagcat
    72301 tggttgaaac tggttctagg atggatgatg taatatttga ggaatttaaa ggtacaggaa
    72361 atatggagct acatttagat agaaaattag cagaaaaaag aatattccct gcaatagata
    72421 tttacaagtc tggtacaaga agagatgatt tattgcttga tgatgaagaa aagactgctc
    72481 tttggagatt aagaagagaa atgagtaata attcagtaat ggaaattaca gataaagtca
    72541 ttgaacttat aaagagaact aaggacaata aagagtttgt aaaatcaata aagaatttgt
    72601 aaaatcaata atacaaatgc aaatatggat tatataaact aatagaaaaa tcacttgaat
    72661 ggcataataa gttgtgctat aataatgtag ttgataatgt aaaaagaaag ttaatataat
    72721 taattttttt aaataaagag aagaggtgac tataatgcaa aaggaaatac aaccaaaata
    72781 caatccagtt gaagtgcgtt gtgcttgtgg gaacacattt gttgctggtt caactaagga
    72841 cgaaataaaa gttgaaatat gttcagagtg ccatccattc tatacaggaa aacaaaagaa
    72901 catagaaaaa ggtggaagaa tcgacaaatt caagaaaaga ttcaaaatgg actaattttt
    72961 ataaaagtgg agttggagga agccaactcc tattttatta caaaaaaaca ttcatattct
    73021 actttaaatt gtctttttgt attataataa taaatatgta aaattgagta ttctaaatac
    73081 aataaaatga ggtgagtgga tggcaaaaca agctgtaggt gggcaagctg ttattgaagg
    73141 tgtaatgatg cagtcaaaag acaaaagagc ggtagctgtt agaaaaagtg acggagaaat
    73201 agcactaaaa gaagatagaa taaaaagttg ggtaagagat aagaatatag ataagatacc
    73261 ttttgttaga ggttcttttg ttatgataga tacaatgatt caaggcataa aaagcttaaa
    73321 cttttcttca gagtttttta tggaagaagc tgaagaggat aaatttgatt tatttataaa
    73381 gaaaattttt aaagataagg caaatgatat aattataata ttttcattgg tcatagcaat
    73441 gttactttct gctggattat tcatttttat acctacattg gtaggaggag ctttttctaa
    73501 agtaatgcct aatgatttta tgcttaattt aatagaagga atcataagga tagctatatt
    73561 atttgcatat atagtattga tttcacgaag taaggatata gaaagagtct ttcaatatca
    73621 tggagcagaa cataaatcta tatattgcta tgaaaatgat ttagaactta cagtagagaa
    73681 tgctagaaaa tttaaaagat tacatcctag atgtggtaca aatttcctat ttatagttat
    73741 ggctgtatca ataatattgt ttgcattttt tggttggcca aatccaattc ttagaatatt
    73801 tatgagaatt atatgtgtgc ctatagtagc aggtttatct tatgaggtaa ttagagttct
    73861 tgggaaatat gataatggat ttactaaaat tattgcatat ccaggaatga tgttgcaata
    73921 ttttacaaca aaagagcctg atgatgagca attagaagtt gctttggaag cattgaaagc
    73981 agtagtagat tagagaaaag gatatttgtt atgacgataa aagatataat tattaaatat
    74041 tcagataaac taaaagatat aagtgatact ccaagattag atacagagtt attgttacaa
    74101 aaaacattgg gtgttgatag attatatatt cacttaaatc tgaataaaga gctaactgaa
    74161 gaacaaaaaa caaaatttat gggttttgca gaagaaagat taaatggaag accaatagca
    74221 tatatagttg aaaataggga gtttatggga ttagattttt ttgttaagga aggcgtattg
    74281 attccaagac cagatacaga aactttagta gaagaaataa ttgaaatatg tagagaaaaa
    74341 aaagatgtaa gtatattaga tataggaact ggttctggag ctattacaat aagtttagca
    74401 aagtacattg aaaattctaa aatcatgtct tttgatatat cagagacagc attagaaata
    74461 gctaaaaaaa atgctattat aaatgaagtt ggtgaaaaaa taaagtatat taattctgat
    74521 ttatttacag caataagtga tagtaacata aaattcgata tcatagtttc aaatccacca
    74581 tatattaaaa aacaagatat agaaactctg cacaaacaag ttaaagatta tgaaccatat
    74641 aatgctcttg aaggtggaga agatggatta gacttttata gaagaataac agaacaaggt
    74701 aagaaatatt taaataagtg tggaatatta gcatatgaag ttggtcataa tcaagctgaa
    74761 gatgtaataa atattatgaa aagtaatgga tataaaaaaa tatacacaaa gaaggatatt
    74821 caaggcattg atagagttgt tataggttac aatatatgat ataatcaaca attgatatgt
    74881 tacatttaat cgaggtgaaa gtatgttaaa aaaattagag gtattggaag atacatataa
    74941 agacttaagt gaaaaaatag gtgatccgga tgtaataaat gatcaaaaag tttggcagaa
    75001 atatataaaa gaacatgctg acttggaacc tattgttatg aaatacagag agtataaaag
    75061 cgttttagat agtataaaag aatcaaaaga aattttacaa gaagagtcag atgaagaatt
    75121 aagagaatta gctaaaatgg agttagctga gatggaagaa aaagtagcac ctctggagga
    75181 agaaataaaa atactattat tgcctaaaga ccctaatgat gataagaacg ttatagttga
    75241 aattagaggt ggagctggag gagatgaagc agctctattt gctggtgatt tatttagaat
    75301 gtactcaagg tatgctgaaa gaagaagatg gaaaatagaa ttattgagtg caagtgatac
    75361 tggagttggt ggatataaag aagtatcttt tatgataaaa ggtaaaggtg cttattcaag
    75421 attaaagtat gaatctggag ttcatagagt tcaaagaata ccatcaactg aatctggtgg
    75481 aagaatacac acatcaactt ctactgttgc agtattacca gaagttgaag atgtagaggt
    75541 tgaaataaat ccaaatgatt taagaataga tgttttccgt tcttcaggta atggaggaca
    75601 aagtgtcaat actactgact ctgctgttag ggtaacacat atacctacag gtgaagtagt
    75661 atcttgtcaa gatggaaaat cacaattaaa aaataaagag caagctttaa aaatattaaa
    75721 agctagactt tacgataaag cattggcaga acaacacaaa gatatagcag cagaaagaaa
    75781 aagccaagtc ggaacaggag acaggtcaga aagaataaga acatataatt tccctcaagg
    75841 tagaataagt gaccatagaa taaatttaac tttatataag ttagatgcat tcttagatgg
    75901 agatatagat gaaatgatag atgctttaat tactgttgac caaacagaaa aaatgactgc
    75961 aatataagta atgttttaaa gaagctgttt cttcctagaa attattttct attttgaaac
    76021 agctattttg cattttaggt catgttatca tattctattg tatataattg ttatatacaa
    76081 gtataggagg gttatatgat actaaaagta acaataattg ggcttttggc aggtgttata
    76141 gggacaggat taggaggagt aatatcagcc atttttaaaa gagaggtcga taaatatcta
    76201 agttttttta tgggattatc tggtggaata atgttggctg tagtggtgtt tgatttaatg
    76261 aaagaatcca tggacaaaat ggggataatc aatacagtta tatttacgtt tgttggagct
    76321 ctcataacta tgtacataaa aacaaaatta gatgtgtctg gaaatatggc atctggatat
    76381 cttatattca taagtatatt actacataat ttaccagaag gactagccat tggttcttct
    76441 tttatgtcaa ctgaaagttt aggtattaca cttgctatag ttataggtct acataatata
    76501 ccagaagggt tagctatggc attaggctta gtttgcaata aaatgaaact aagtaaagtt
    76561 attttgttta ctgtaatagc tggattacct atgggtctag gaagtttttt aggtgtttat
    76621 tttggaggag tatttacttc tcttatagga gtatttcttg ctacagcagg aggtactatg
    76681 atgtatgttg tattggaaga aatttttcca cattcaaaaa gtgtgtattg tataattggt
    76741 ttcttgttag gtacaatgat tgtaaattat atataaaatt aaaatgaaag caggcataca
    76801 aaagatgaaa actattataa gtaatattga tataaataat attgattatg aggaaataaa
    76861 aatacaagca aaacttctta gagaaggtaa aacagttatt tttccaactg agacagtata
    76921 tgggttgggt gcaaatgcat tagatgaaaa tgcagtaaag aagatttatg aagctaaagg
    76981 aagacctagt gacaatccat tgatagtcca tatatatgaa aaagaagaag tatatgactt
    77041 agccaaagat ataagtgata aagctaaact tgttatagaa aagctttggc caggacctat
    77101 aacaattata ttaaataaaa aagatataat tccatacaaa actagtggag ggcttgatac
    77161 agttgcaata aggatgcctt ctaatgttat tgccagggca ataataaaag aagctggtat
    77221 acctattgca gctccttctg caaatatctc aggtcgccca tctccaacaa aagcaaaaca
    77281 tgtatatgaa gagatgaatg gaagagtgga tggaatagtt ttaggaggag acagtaattt
    77341 tggattggag tcaactgtat tggatttaac agaagagact cctatgatac tgagaccagg
    77401 aagtataact aaagaagttt tagaggaact tcttggagaa gtaaagcttg acccatcatt
    77461 aagtaaaaaa gaagataatc aaaaagctaa agctcctgga atgaaatata aacattattc
    77521 tccaaatgca gatgtatata taatatctgg aaaaagagaa aatgtagcaa caaagattaa
    77581 tgatatgata aaatctaata gagacaaagg tctaaagaca ggtgtaatgt gtattagtag
    77641 aaaccgagag ttttatgatg gagaagtaat cgatttagga aactctcttg aagaagttgc
    77701 aagtaatctg tttgatgctc ttatagaaat ggacaaaaag ggtgttgatg tcatatattc
    77761 agaagagttc cctaagactg gagttggaca agcaattatg aatagactac tgaagtcagc
    77821 aggatacaaa gtgataaagg cttaagaggg agttgtaaaa tatgaatata cttattgtgt
    77881 gtacaggtaa tacttgtaga agtcctatgg ctgaggctat actaaggaaa gcaattaaag
    77941 aatctggaag aagtattgaa gaatattcta tatcatcagc aggtatatct acagcaaatg
    78001 gaatgggtgc ttctgaaaat tctatagaag tactaaaaga aatcggtata gacttatcaa
    78061 atcatagaag taaagtaatt actaaaaaat taattgatga atcagatata atactaacaa
    78121 tgactaaatc tcataaagaa attttagtac aagcagttcc aaaatgcaaa gaaaaagtgt
    78181 atacttttaa agggtttgca aataaaaatg aggaagatat atctgaccca tttggtggaa
    78241 atttggatat ttatagaagc actatgagag aaataatgta ttctgtcaac gaaatagtaa
    78301 aaaaaatatg aaacggagga taaacaaatg aagataggat taggctgtga ccatggagga
    78361 tataatttaa aaaaagaaat aataagctat ttagaaagta aaggcataga atgtgtagat
    78421 tatggaacta ataatgctac agattctgtt gattatcctg tttatggaga aatagttgca
    78481 aattcagtta taaataaaga agtagattat ggaatattat gttgtggtac agggatagga
    78541 atatctttag ctgctaataa ggttcctggg ataagatgtg cagttgtatc agatgtattt
    78601 tctgcaaaaa tgtcaaaagc acataatgat gcaaatatgt tatcattagg cgaaagagtt
    78661 ttaggaaaag gtctagcact tgagatagtt gaagcatgga ttaatacgga ttttgaaggt
    78721 gatagacatg ctagaagagt aaacatgatt aaatcaatag aagaaaaaca taataaataa
    78781 taaaaattac agttttatca ggaggaatta tcaaaatgag caaagtggta gagacaaacc
    78841 atccattaat acaacataaa ttaactttaa tgagagataa aaatactggt tctaaagact
    78901 ttagagagct tttaactgaa attgcaatgt taatggggta tgaaataaca aaagatatac
    78961 cattaaaaga tgtagaaata gaaactccta ttcaaaaaac atcatctaaa gtagttgcag
    79021 gtaaaaaatt agcaataatt ccaattttaa gagcaggtct tggaatggta gatggattag
    79081 tgagcttaat gccagcagca aaagttggac atgtaggact atatagagac ccagaaacat
    79141 taaaaccagt tgaatattat tgtaagcttc ctcaagacat aggagaaaga gatataatag
    79201 tagttgaccc tatgcttgca acagggggtt ctgctgtagc agctatagat ttacttaagt
    79261 ctaaaggagc taaaagtata aaattagcta atttagtagc tgcaccagaa ggtatagcag
    79321 aagtgcaaaa atatcatgat gatgttgata tatatgttgc atcagttgac gaaagattaa
    79381 atgaacatgg atatataatt cctggtcttg gtgatgctgg agatagattg tttggaacta
    79441 aataaaaata aataactata aatatttatt agggactttc ttatatagtg tatataattt
    79501 tatgtaagaa ggttcttttt tatatatttt ttctcaaaat aggaattatt gaattgataa
    79561 atttctcgaa ttgagaataa aaagttttta ccaattaaaa aagattgctt attttacaag
    79621 gttttataga atagtagtct attttaatgt ggcatgttag ttgcttacga ttaagattat
    79681 aggtattaag tgtattagtt aaattgagaa ttgaatatta ataatattat tgggagtggt
    79741 aatacatgaa gaattgtata gtagtaagag gggctggaga tttagcaaca gcagttattc
    79801 ataaattaca caacagtggt tttaaagtag ttgcgttaga aatagaagag ccattagcta
    79861 taagaaggca aatttctttt tgtgaggctg tttatgaaaa aaaagtaact gttgaaggtg
    79921 tagaatgtat attttgcaat actgaaaaag aaatagaaga agttttatct caacataaag
    79981 tagccttgat tatagaccca aaaggagaaa aattatctaa attaaatcca atcgttttgg
    80041 ttgatggaat actcgctaag aaaaacttag gtacaactaa agatatggca ccacttacaa
    80101 tagctttagg tcctggattt tgtgcaggag aagatgtaga tgttgttata gagacaatga
    80161 gaggtcataa tctaggaaga ataataacta atggtagagc agaaaaaaat acaggagtac
    80221 caggagcaat aaaaggtttt tctaaagaga gagttatgca ttcacagtat gatggcataa
    80281 tggaaaatgt atgtaagata ggtgatatag ttgaaaaggg agacctactt tgctatatta
    80341 ataattatga aaaaaaacat gaagttagag caacaatatc tggagtcctt agaggtttat
    80401 taaaggatgg agcaaaggta aacaaaaatt taaaaatact agacatagac cctagaaaag
    80461 aagaagttaa gaatgctttt acaatatcag ataaagctag atgtatagct ggaggggttt
    80521 tagaagccat actaaacaat gggatttatc cccaaaatta atttatatta gataaagcta
    80581 ttaatatttt attaagatga tataataaat ttaatagatt aaagagagca tatgacgggt
    80641 atttaaaatt taaatggtaa aaatgctctt tttttattgg acattcaatt aacatgtgta
    80701 tataatataa aaataagtat ttatttaggt tgaaatctaa taaatatata ataccagtac
    80761 ataagcaaag aggagaaaag taaattatga gaccatcatg ggatgaatac ttcatggaaa
    80821 ttgcagaagt agtgaaaaag cgttcaactt gtattagaag acaagtagga gctgtaattg
    80881 taagagacaa acaaatatta acaactggat ataatggttc tccgagaaat cttgaacact
    80941 gtgaaaatat tggatgtaag aggcaggaat taaatattcc ctcaggagaa aggcatgaat
    81001 tatgcagagc attacatgct gaacaaaatg cgataataca agctgctcat aatggtatta
    81061 gtgtagatgg ggcaactttg tatgttacta caagaccttg tgttttgtgt gcaaaaatgt
    81121 gcataaatgc aggtatattg aaaattgttt atgaaggtga ttatccagat gatatgtcta
    81181 cagaattatt aaaagaagca ggaatagaac tcataaaatt ttagtggata aaatttatat
    81241 gacaataaat gtcaaattat gacactgaaa tacaatggta tcaaatgatt aaaagaaagt
    81301 atttgaaaaa tcatcagatt agtagtaaga tatattttat aattaaataa atttatgaga
    81361 tagattaatt acatgttatt tattttataa taatgaggga tactatttat gagtaaaaga
    81421 aatacacata cagaaattgc aaagttgttt agtttaataa gccaaatagg attgatgatt
    81481 gtaatatcaa tattaggatg tactttctta ggaaaatttt tagatagtaa attgaatact
    81541 actccagttc tgacaataat atttttattg ttgggtgttg gaggtgcttt tagtggtgtt
    81601 tataaaactc taatagtata tacacgaagg aagtgatata ttggatataa aattacttaa
    81661 ccaggtaagg tcagtaacaa aaggtatagt aatatttgat gtagttttaa ttgtgctaat
    81721 gttgataaca tcaacattaa gtaaaccagt attattagga cttatatttg gctctataat
    81781 agctatgtta aattttagat tattggcgat atcactggaa aaatcagtga catttcctgc
    81841 tgggaaggca caagcttatg catcagcaca atatgctgtt agattattta taatggcagt
    81901 tgttctaatt gcatcagcta cagtaccaca tttaaatata atcggaacag cattgggatt
    81961 attgagcaca aagtttgtca tattatcaaa aaactttata aataaattaa agaggaagga
    82021 ggcataagta tgaatcaagc gcattattat ctcataggaa actttaagat tagtgaaaca
    82081 atactagtaa gttggggaat aatggccttt ttagcgatag catcttattt tttgactaga
    82141 aacttaaaaa aagttccaac tagtaaagtt caaatattct tagaatttgc agtaggtggt
    82201 cttgctaaaa tggttacaga tgttatgggt aaaaatacag taaaaagaat gccatatatg
    82261 ataccataca taggaagctt gtttttattt ttcgcatgtt caaatttaag cccattactt
    82321 ggattaaggt caccaacaac cgacttagat acaactgctg catgggcaat gattacattt
    82381 tttatgattt attttgcagg agttaaattt aaggggttat catactttaa agaattggct
    82441 caaccacttg ccataatgtt accaatcaat attataggtg agttagctag accaatatca
    82501 ttaagtttcc gtccatttgg gaatatttta ggtggaacaa taataatggg tctgttttat
    82561 caacttttag gttttatttc tagtttaata ccaggattat caataccaat tggagaaata
    82621 ttaataccag tcccattaca cttgtacttt gacttatttg caggattgtt acaagcatat
    82681 atatttataa tgttaacaat ggtatttata tcaagtgcag gagagttaga ttaagaaatc
    82741 aacttatatt aagataaaaa taaaataatt taaaaaatta aagttttaag gaggaaataa
    82801 ttatggaaac agcaatagta gcggcagcat cagcaatagg agcagggata gcagttgcaa
    82861 caggtatagg tgcaggtata ggtcaaggta tagcagcagc taaagctgca gaagcagtag
    82921 gaaaccagcc agaagctaaa ggtgatataa catcaacttt attactagga gttgctatag
    82981 cagagtcttc agcaatatat ggtttggtta tatcaataat acttctattc gtaaatccat
    83041 tctttaaata cttaggaatg tagatttagt ccttaaatat tttgagatag gtttataggt
    83101 aaatcatctc aaacttataa tcatgagatg aactttatca tctcgtgatt ataagtagtt
    83161 atgatttatg gaaaggagga taattatgga aaaagcacta gtaggtataa cgtgggaatt
    83221 tgtgttccaa attgttaata cttttataat atttttactt ctgagaaagc ttttattcaa
    83281 gccagtatta aatataattg aatcaagaga aaatgatatt aaaagtgatt tggtagaagg
    83341 cgaaaaagca aaaaatgaag gtttagctct gaaaaaagaa tatgagtcaa aaatcaattt
    83401 tgccaaagat gaaggtcaag aaatcataaa acaagcaact ataagagcag agcagaaatc
    83461 agatgatata gtaaatactg caaagaaaga tgctcttgat ataaaagaaa aagcaaacaa
    83521 agatatagaa caagaaagac aaaaggttat aaatgaaatc aaaaatgata tatctaacat
    83581 agcactactt gcagcatcta aagttattga aaaagattta gataaatcta aacatgaaga
    83641 attgatagaa aactttataa aagaggtagg ggaagctaaa tgataaatgt aatagcaaat
    83701 agatatgccg aagccctatt tcaattagga gaagaagaaa attcaactga tgtcttattc
    83761 aaagaactag aaaaagtagt agatatgatg actaaagtta gtaaagattt ctacaaagtt
    83821 ttaaaatcac cattagtttc aaaatcagaa aagaaaaact tggtagaaat tatttttagt
    83881 aaagaagtaa gttctaacat aaaaaacttt ttaaaagttt tagtagataa agatagaata
    83941 tcatatttag aagatatcga attagcttat aaagaattat taaataagaa aaacaatgta
    84001 attgatggag tagcaataag tgctattcca atgagtgaaa cagatattaa agaacttgaa
    84061 gtcaaacttt caaataaata caacaaaaat gttactatag aaaatgttgt tgacaagact
    84121 atactagggg gagttctagt tagaattgga aatgaacaaa tagatggcac tgtgaaaact
    84181 cgtcttgata agatgaaaga aaagctatct gaagtaatat cttaagaatg gcggtgaacc
    84241 catgaactta aaacctgaag aaataagttc tataattaaa cagcaaataa aaaattatga
    84301 gaataaagtt gagttgacag atacaggtag tgttttaaca gttggggatg gtatagcgag
    84361 tgtatatgga ttagaaaaag ctatgtctgg tgagttgcta gagttcccag gtgaaatata
    84421 tggtatggca cttaacttgg aagaagaagt agttggagct gttatccttg gagatgacag
    84481 tgaaataaaa gaaggcgata tagttaagag aactggaaga atagttgaag ttccagttgg
    84541 agaagcttta ataggtagag ttgtaaactc actaggtcag ccaatagatg gaaaaggacc
    84601 tatagcgtac acaaaaacta gaccagttga atctgaggca cctggtataa tagatagaag
    84661 gtctgtttat gaaccattac aaacaggaat caaatcaata gattcaatga taccaattgg
    84721 tagaggtcaa agagagttaa taataggtga cagacaaact ggtaaaacat ctatagttat
    84781 tgacactata ctaaatcaaa aaggaaaaga tgttatctgt atatatgtag caattggaca
    84841 aaaacgttct actatagctc aattagttag ctctttagaa aaaggtggag ctttggatta
    84901 tacaatagta gtttcagcaa cagcatctga atcagcacca cttcaatata tagcaccata
    84961 tgctggagca gctatgggtg aagaatttat gtacaatggg aaacatgtac ttatagtgta
    85021 tgatgattta agtaaacaag ctgttgcata tagagaaatg tcattgttac ttagaagacc
    85081 accaggacgt gaggcatatc ctggagatgt attctattta cattcaagat tacttgaaag
    85141 agcagctaag ttatctgatg aattgggtgg aggttcaatg actgccttgc ctataataga
    85201 aactcaagct ggtgacgttt ctgcatatat accaacaaat gttatatcta taacagatgg
    85261 tcaaatatac ttacaaccag agttattcta ttcaggtgta agaccagcag ttgaccctgg
    85321 tatatcagta tcaagggttg gtggttctgc gcaaattaaa gcaatgaaaa aagttgcagg
    85381 aacattaaaa cttgcatatt cacaatatag agaacttgca gcattctcac agtttggttc
    85441 tgacttagat gaagatacta aaaagagact tgctcaaggt gaaagaatcg ttgagatatt
    85501 aaaacaaggt gagcatcaac caataaaagt tgaaaatcaa gttatgataa tatatgctgt
    85561 tataaataat catttagagg atattccgat agataatata gctagatttg aatcagaatt
    85621 gtatgcattt gtagataata attatccgga aatatcaaga aaaatattag gtggagaaga
    85681 cttcactcat gatttaacag atgcaataaa tgaatttaaa gaaaagtttg ttgttgaagt
    85741 ataatccttt ttaaaaaagg aggtaaatta attggcagga gctggaatca aagcaatcaa
    85801 aacacgtatg ggaactgttg aaagtacaaa gcaaataact aaagcaatgg aattagttgc
    85861 atcttctaag cttagaaaag caaaagaaaa ggctgaagat tcaagagaat attttaatac
    85921 tttatacaat acagtaaaag atattgccca aacaacacgt ggaattagaa atgaattttt
    85981 aaaagaaaga gaagtaaaaa ataaatgcta tgtagtagta gctggagaca gaggacttgc
    86041 aggtggatac aattctaatg tattaaagga atctgtctct catatgaaag gtaaaaagga
    86101 aacagtgatt actgttggaa agaaagcaca tgaatttttt tctaaaagaa actacaatat
    86161 agcaaaagat ataaatagtg ttgaagcttg tggatatgaa gatgcgacag aaatttcaca
    86221 aactattatt gacctgtata aaaaaggtga agtagatgaa gtttatattg cttatacaaa
    86281 atttaaatct gctttatcac aagaagttga aattttgaaa ttgcttccat tagtctttga
    86341 aaaagataca gacgaacaag gaatggcagt aaaagaagaa aaacaaaata gatcaaaagt
    86401 acaatatata ccatcagcag aagcagtttt aagttatatt gtacctcagt ttatatcagg
    86461 tacagtatat ggtggaattt tggaatcttt tgcatcagag caaggtgcta gaagaactgc
    86521 aatggaatca gccacagaca atgcgaatga aatgctatct aatttagagt taagttataa
    86581 cagagcaaga cagtcagctg taactcaaga aataacagag atagttggtg gagttgaagc
    86641 tctaaaatag ggaggttagg aaatggcaaa tgtaggtaaa gtagtacaga ttgtaggagc
    86701 tgtactagat gttaagtttg atagtgaaca aagcctacct aacttattaa atgcgttagt
    86761 aataaagtta ggagataaag aaatagttgc agaagttgct caacatatag gtgatgatac
    86821 tgtaagatgt atagctatga gtgcaacaga cggacttgta agaggtatgg aagttgtaga
    86881 tacaggaggg ccaataagtg ttcctgttgg agatgaaact ttaggtagaa tattcaatgt
    86941 tcttggaaaa ccagttgatg ggaaaccagc tccaaaatct gcacctaaat tacctataca
    87001 tagaccagca ccggcgtatg atgaactaga aactacagca gagatactag aaactggtat
    87061 taaggtagtt gacttactag ctccatatct aaaaggtgga aaaataggtc tatttggagg
    87121 agcaggagta ggaaagacag ttctaataca agagcttata aacaatattg ctaagcaaca
    87181 tggtggtatt tctgtatttt caggagtagg agaaagaaca agagaaggta acgaccttta
    87241 tggcgaaatg agtgagtctg gagttataaa taaaacagct ctagtatttg gtcaaatgaa
    87301 tgaaccacct ggagcgagaa tgagagttgc tttaactgga cttacaatgg cagaacattt
    87361 tagagatgag caaggacaag acgttttact tttcgttgat aatatattcc gtttcacaca
    87421 agctggttca gaagtttcag cacttctagg acgtatgcca tcagctgttg gttatcagcc
    87481 aacattagct actgaaatgg gtgcacttca agagagaata acatcaacta agaaaggttc
    87541 aataacatct gttcaagcag tatatgtacc agcagatgac ttaactgacc cagcaccagc
    87601 tacaacattc tctcacttag atgcaaaaac agttttatca agacaaatat catcactggg
    87661 tatatatcca gcagttgacc ctcttgaatc tacatcaagg attcttgacc ctagtatagt
    87721 aggaaaagaa cattatgaag tagctagagg tgtacaatca atacttcaaa gatataaaga
    87781 acttcaagat ataattgcta tacttggtat ggatgaatta tctgatgaag ataagttaat
    87841 agttgcacgt gctagaaaga tacaaagatt cttatctcaa tcattcacag ttgctgagca
    87901 atttacagga aatccaggtc aatatgttcc tgttaaagag actgtaagag gatttaaaga
    87961 aattcttgaa gggaaacatg atgacttacc agagtcagca ttcttatttg taggaacaat
    88021 agaagacgct gttagaaaag cgaagggaag tatgtagtca tggccagtga attttcattg
    88081 aaagttgtaa ctccaagtaa tactttttat gatggagatg ttgaaatgat agtagttaga
    88141 actacaaaag gagacaaagg ggtgttgaaa ggtcatatac catttgtttc aggtatacct
    88201 gtaggaactt taaagataaa aaaagaggga agttttaaag aggcgaaaat agcagaagga
    88261 ttcattaatg taactcaaga taaaactgtc atattgacag aatctgctga gtggatttaa
    88321 taaattaatt tagagtataa aaagtcattt tgaccaaaaa aacttttggg taaaatggct
    88381 tttttgtgtt ttggtgttaa taaaataacg ataaaattgt aagtttttag tgataataaa
    88441 ttcacaaaat gtttaaattt actgccaaat tatgttgtaa ttaataagat aaagaagatt
    88501 tagatagctt ttatgtaagt gaaaaagtct tcatataaga aatacatata aaatttttat
    88561 aaaatttaaa aaatttgctt agttgtgtag tataataaat aatataatag atttgtatat
    88621 aatattcatt acaaataatt ttaaaagtta cagttttatt ataatgatta ttaaattaag
    88681 ataagtaaca taaactaaat aataatgtgt attatcgata gtaaatttat aaattcatta
    88741 ttaattattg aaagaagtat tataaatttt ctggaggaac aatgaatata tttgatattg
    88801 gcgtagatat aattgaaatt gatagaataa gaaaggctgt agacaaaaat aataggtttt
    88861 tggagaagat atttacagat agagaaatag agtattttaa ttctaagaat tttaaagcag
    88921 aaagtatagc aggtaatttc gcagccaagg aagctataag taaatctata ggtacaggaa
    88981 ttagagtgtt taattttaaa gatatagaag ttctcagaga tgaaatggga aaaccaatag
    89041 taaaaactta taataatcta gcaaaaatgt gcatagatta taatgtttta gaaataaaag
    89101 tttcaatatc acattcaaaa gattatgcta tagcaaatgc gataaccata attaaggact
    89161 aaggagtgat tacattatga tggataaaac agcaaaagaa ataatgacaa cagatgtaat
    89221 agtagcaaaa caagatgata gtatagcaga tgtagctaat atgctaattg cagaaaaaat
    89281 aggaggtctg ccagttgtag attcagagaa tagagttgtt ggaataattt ctgaaacaga
    89341 tattcttaaa aaagaaaaat atatagaagc acctctctat ataaatctat tacaaggatt
    89401 gattttctta gatgacttaa aaaaagttga aaaagatata aaacaagtag ctgcttataa
    89461 ggttggagaa cttatgtcta aagatataat aaaggttcat gaagatgata agtttgatga
    89521 tgtagctaat gtaatgatta aaaaatcaat aaacagagtt cctgtagtag atgatgacaa
    89581 caaacttaaa ggtataattt gtagatatga tataataaaa gctttataca atgaataaac
    89641 tgaagtagga ggtgtgatgt gagaaaaaag tggaccatag tatgtattat gttcttggca
    89701 ctggttataa ttgtaatagg atgccaaaaa cgacagtcca caaaagaaga agtatacaaa
    89761 gattttcaaa agcagatttc tgatatgaat tattacagtt gtaaagctga agtagaagta
    89821 gttggaaata aaagtccaca caattatgtt ttaattcata cttataaaaa aaccgataac
    89881 tataaattag aagtaatttc cccaaaacat ttaaaaggga aaagtataga atatcaaggt
    89941 gataaaatat tagttaaaaa tccaaagatt agtgatgtag tggagttacc taatacagga
    90001 aaaaataatc aatatctttt tgtaggagac tttataaaaa actatcttca aaatgaggag
    90061 atgaaagtaa agttatccaa aggacatttg gttttagaga cttttattcc tggggataat
    90121 aaatatttta acaagcaagt attatatgta aatgctgaca caaaaaatcc tgaaaaaatg
    90181 gaagtgttag ataaagaggg agtgccaaga tttacagtaa aatacaaaga ttttgaatac
    90241 agaaactaag ggggactaaa gacatgcaaa aaataacagt gcctacatgg gcagagataa
    90301 atctagataa cttaagattt aacttaaata atattaaaaa tttattagaa gaagatatta
    90361 agatttgtgg agtaataaaa gctgatgcat atggacatgg tgcagtagaa gttgcaaaat
    90421 tgctagaaaa agaaaaagta gattacttag cagtagcaag aactgctgaa ggaattgaac
    90481 ttagacaaaa tggcataaca cttcctattt tgaacttggg atatactcca gacgaagctt
    90541 ttgaagattc tataaaaaat aaaataacta tgacagttta ttctttagaa acagcacaaa
    90601 agataaatga aattgcaaaa tctttaggag aaaaagcctg tgttcatgtt aaaatagact
    90661 cagggatgac tagaataggt ttccaaccta atgaggagtc agtacaggaa ataatagaat
    90721 taaataaatt agaatatata gatttagaag gtatgtttac tcattttgct acagctgatg
    90781 aagtaagtaa agagtacact tataaacaag ctaataatta taaatttatg tctgataaat
    90841 tagatgaggc tggtgtaaaa atagctataa aacatgtatc aaacagtgca gctattatgg
    90901 attgccctga tttaagatta aatatggtaa gagcaggaat aatattatat ggtcattatc
    90961 catctgatga tgtatttaaa gatagattag aattaagacc agccatgaaa ttaaaatcaa
    91021 aaatcggaca tataaaacaa gttgaaccag gtgtaggaat aagttatgga ctaaaataca
    91081 caactacagg taaagaaaca atagctacag ttccaatagg atacgcagat ggatttacta
    91141 gaatccaaaa aaatccaaag gttcttatta agggagaagt gtttgatgta gttggtagaa
    91201 tatgtatgga tcaaataatg gttagaattg acaaagatat agacataaaa gttggagatg
    91261 aggttatact atttggagaa ggcgaagtta cagctgagcg tatagctaaa gacttaggaa
    91321 ctataaacta tgaagtgtta tgtatgatat caagaagagt tgaccgtgtt tatatggaaa
    91381 ataatgagct tgtacaaata aacagttatt tgctaaaata aaaccatgat attataatct
    91441 gggaggcgat tttgtgtacg ataagagtaa agaaaaaata gaagttactt tacctgactc
    91501 tctgatttct gaagttgata gtatagttca gatggagaac agtaacagag aagattttgc
    91561 aaaagctgct tttcagttct atataactca gaaaaagaaa attcatatta aagaatctat
    91621 gaaaacgggt tatagagaaa tgggtcaaat taatctgtca ctagctgaat taggtatgac
    91681 agttgaagaa gtatcttctg atgataaaaa tgaagggaag attgcccaag gtgagtacta
    91741 attgtgaaat aaagcgtggt gatttatatt acgctgattt aagtccagtt gttggttcag
    91801 agcagggagg cgttagacct gttctgataa tacaaaatga tgtaggtaat aaatatagtc
    91861 ctacagttat agtatcagct ataacatctc agattaataa agccaagtta cctactcatg
    91921 tagagataag ttccaatgaa tatgggctta ataaagactc agtaattctt ttagagcaaa
    91981 ttagaactat cgataaaaag agactgaggg aaaaaattgg ttgtctagat gaaaatatga
    92041 tgataaaagt agatgatgga cttcaaataa gtttaggatt gtttactttt taaagaggga
    92101 tttgtctttt attagacaat cccttttttc ttttaaatat ctcttaaggt ttaattttaa
    92161 tgtactatgt taataaaatt aaaaataacg caaaaaaata gcataaaagt gatataataa
    92221 tatggaattg atataaaatt acgaactcaa gggaggtaat tgcatgagag accataaagg
    92281 attaaatgag attgcgcgta tcataagaag agatatagtt tcaatgatac atagagccaa
    92341 atctggacat ccaggagggt cattatcagt agttgaaata cttactgcgt tatactttga
    92401 tgaaatgaat gtggattctt caaatcctaa aatggaggat agagatagat ttgtattatc
    92461 aaaaggacat gctgcaccag cattatatgc tacattggct gaaaaaggtt attttgataa
    92521 ggaagaactg aatggattaa ggaagatagg aaggatgtta caaggtcatc cagacatgaa
    92581 aggcacgcca ggtgtggaaa tatctactgg ttctttaggt caaggttttt cagttgcatg
    92641 tggtatggct atggcatcaa agttggataa tgctccgtgg aatgtgtata ctttgcttgg
    92701 tgatggtgag gttcaagaag gaattgtttg ggaagctgct atgagtgctg cacattataa
    92761 acttgataat ttaattgctt ttttagataa taatggactt caaatagatg gagatataga
    92821 aagcgtaatg agtttaggtt caatagttga taaatttaaa gcttttggtt ggaatgtaat
    92881 tgagatagat ggacatgatt ttgaccaaat atttgcggct cttgatatag ctaaatcaac
    92941 agttaaaaaa cctacaatga tagttgcaaa aactataaaa ggcaaaggaa tatcttttat
    93001 ggaaaatcaa gcaggatggc atgggacagc tccaagtgat gaggagctag aaaaagcctt
    93061 gcttgaatta ggaggtgctg acaatgagta aaatggcgac gagagaagca tatggtaaag
    93121 cattagtaaa attgggtcaa ataaatgaca atgttgtagt attagatgca gatttatcaa
    93181 agtctacaaa aacacatgat ttttacaagt catttccaga tagatttttt aatatgggta
    93241 tagctgaaca aaatttaata ggcgctgctt gtggattatc aactgctggt aaaatacctt
    93301 ttgcaagcac ttttgctatg tttgctacgg gaagggcttt tgagattata agaaattcag
    93361 tttgttatcc aaagctaaat gtaaaaatat gtgctactca tgcaggtctt actgttggag
    93421 aggatggagc atctcatgaa agtgtggaag atattgctat aatgagagct ataccaaata
    93481 tgacagttct tgttccagct gatggagttg aaacagaaaa aattattttt gaaatagcta
    93541 agtataatgg acctgtttat gttagattag ggagaagttc agtaccagtt ttatttgatg
    93601 aagattataa atttgaaata ggaaaaggta cagtcttaag agaaggaaag gatgtatcaa
    93661 ttatagcttg tggaattatg gtaaatgaag ctctattagc acaagaaaag ttgcaagaag
    93721 aaggtataag tgctagagtt ataaacatgt cctcgataaa acctatagac aaagatttaa
    93781 tattagaatc agcaaaagaa acgaatgcta ttgtaactgt agaagaacat agcataattg
    93841 ggggattagg ttctgctgta agtgaggtag taggagagtc ttgtccaacc attgtaaaga
    93901 aagttggaat taaagataca tttggagaat ctggtactcc aaatgaattg ttaaaaaaat
    93961 atgaattaac ttgtgatgac ataataaaga ctgttaaaga agctattatt gcaaaaagaa
    94021 tgtaagagat ataaattatt catgtttgtt aataatataa tatatttaaa agagaggtat
    94081 aaagtgttat attaatttat atctctcttt tttttatatg atatcaatat atcaaaaatg
    94141 taataaaata ttcaaatttt tacaaaaata gagaaaatat tcaaatatat attgactatt
    94201 cagaaaaata tgactaatat ataatttata gagaaactaa ttttatatat aatgactact
    94261 tagataaaag aatctaaaaa aattatgaga ggaggagtag ggtataaaat cagattataa
    94321 gttttaagtt attatactaa aaagctataa aacagttatc atgtatttta tgttaaagga
    94381 aattgtaggt agtttatcga attgtttaat cagaagaaaa aatttcacat ggggaggtaa
    94441 ctgagatatg tcagaaaaag taaatgttaa aacagtcatc agtttcgcag gtgcgtatgt
    94501 agcaacagta atcggttctg gatttgcaac aggacaggaa ataatgcaat tcttctcttt
    94561 ttatggtttt gcaggtatta ttggtgggat aatttcaatg gtattattct catggatggg
    94621 tgcttcagtt atgtcaaaag gtaaagagct tcaacttaaa gaacctatca aaatttatcg
    94681 tgtttattgt ggtaagtatt taggaatatt ctttgaatgg tttggacctt tattcttatt
    94741 tggtgttttc gtagtaatga tttcaggagc aggagcaact ttaactgaat actatggatt
    94801 aaatccattt gtaggtagag taggtatggc agtagtagca ttattaactg tttcactagg
    94861 tcttgataaa ttatcaaaga tactaggtgg aatagggcct ataataataa tctttacact
    94921 tttagttggt ggtataagtt tagctaaaaa cataggtaat ataggagaag ctgcacaagt
    94981 tcttagcact gtaaagatag ctaaaccagt tccaaatgcc tatctatctg gtgtaatata
    95041 tactacttat aacacaattg ttgttatggc attcttaact ggattaggag caagtgctgc
    95101 taacaaaaaa gaagctattt gtggtggtat attaggtgga gtagcactta tggctgcagc
    95161 tataatgatg cacttagcta ttctttctga tataggaaac ttatattcaa aagcaatacc
    95221 atcattattc ttagcagata agatttcacc agtaattgga gttttattct caataattct
    95281 tatattaggt atatatacaa cagctgtacc tttattatgg tcagtaacta atagatttgt
    95341 agatgacaaa catcctaagt ttaaattaat aactttaata gcagctatat taggtcttat
    95401 aggtggcttc ctaccatttg ataagctggt tggtatttta tatccatata ctggatatat
    95461 gggcgtcata atactggttt gtgttcttta tagacagatt acaaaaacat ctggatatca
    95521 agaaggaatc agtgacaaat aagtattttt taatattgta aactcaagag ctatatgaaa
    95581 acaatgaaaa tgttttcata tagctctttt tattttttag ctcgtttatt atgaaataga
    95641 aaaaacatgt tttttagtta cattacatat atttataatt atgtataaat atatactaat
    95701 caataattta gagtctaaga taagtttata aatcatatat ttagaatata tgggaggagt
    95761 gataagattg aatgtaaagt ttaatattaa aggtataatt tatggagtta tagctcttgt
    95821 attcgttata gggggattta tattcatacc aagtatgttt gtagagaaat ctaaacccat
    95881 agattataca gtattacaaa gaaattcaat accagaaaag atattagatg tgatggataa
    95941 gtatacaaat gaagaaagag cattagcggc taaaatcgat aacaaaatat acattatagt
    96001 gactagagga aataataaat atggtataga aatggacaaa atagaaagtg tggttgagga
    96061 aggaaaggat gttttgagag tcaagataaa gtataaagat aaggaagatt cttttccata
    96121 catagttgtt gaaacaaata tgagtgaact tccagataga atagaattaa atgcgacgaa
    96181 ataagaaggt attttataat taaataactg catattgtac aataaagtca tggtttttat
    96241 taatgtaagt aaattgtgta tggttcttat tgttgtaaaa gccatgactt aaaatgctta
    96301 taaagtaaga tattaacagt agtatttatt actacattaa atggggtctg gaaatactta
    96361 atattctaac tatttggagt gataattcta gtttcagtaa ctatgtagtc taattgtgca
    96421 tcatgagttt cttttggaat agaatcgaat atctggaagt caaatgctat gccgatagtt
    96481 atagcatctt ttcttaagtt ttctaaaaat ctatcataaa atcctccacc atatcctaat
    96541 ctatagcaat gtatatcata tgctacagct ggtacaatta caacatctaa ggccttaata
    96601 tcaattgtag gtgatttttc gttaggttct cttattccat atgctccaat tctcaatccc
    96661 tcttttaaat ctgttatttg agtagggatt aatgtatgat tttcttttat tgtgatggga
    96721 cttgatacta ttttctttag agacaaaagt tttttgatta aattatctgt ttgaacttca
    96781 ttgttaaaat ttagataaag cattatatta gttgcatttc ttatatcttc catttgaagt
    96841 aatttttcag ttattaaatt tgaattacta agtacaaagt ttgcattctt attttttctt
    96901 gattcaataa ctttttttct aaattctttt ttcataaaat aattcctccc ttaatatgtt
    96961 ataatgtgta cagcaattgt atttaatata aattttagta taatttattg taataaagca
    97021 atatatttgg gtaaatgtaa taaaaataac agctagtcat ataataataa tagtttatgt
    97081 aaaaggagat gtatcttgtg atttcaaaga agaaagctat ttttttaggg gtgattttag
    97141 taattataac agctatggtt acatcagcat ttcagttgac attggggaat aaagttgtaa
    97201 tatcgaaaga actctatgaa gactataaaa aatatgataa gttgttagga ctagaatcta
    97261 ttataaaaca agatttttat aaaaaagtat cagatactga tttggtaaat ggagcagcaa
    97321 aaggtctatt tctaggaaca aatgataagt attctggtta ttatactaaa gatgaaatgg
    97381 agaatctaat taatgatagt gaaggttctt atgttggtgt aggtatgtat ataggggcat
    97441 caaaagatgg tggcttagta gtagttccca tgaaagattc tccagcagag aaagccggtg
    97501 taaaatcagg ggataaatta gtaaaagtca atggaaaatc tgtctcatat aaaaattcag
    97561 atgaagctgt tcgtatgatg aagggtaaaa aaggtaaaac agttgaactg actatattaa
    97621 gagaagataa acaattgaac tttaaagtaa aaacagacca gataattgag aagagtatag
    97681 aaagtaaagt aattgataat gatttaggat atatagaaat tacccaattt atatcaagta
    97741 catatactga ctttgataaa gctttaaaag aattaaaagc aaaaaatatc aagggattag
    97801 taatagacct tagaaataat cctggtggaa tgctagatat atgtaaagaa gttgctgatg
    97861 agttaattgg tgaaggaact atagtatata caaaagataa taagggaaat actgagtact
    97921 tgaaatctga taaagaaaaa ttgggacttc caatagtagt gttaactaat ggagaaagtg
    97981 cttctgctgc tgaaatatta acagctgcaa tcgttgataa taaagaaggt atttctgtag
    98041 ggactacaac ttttggtaaa gggttggtac aatcagttgt aagattgaag gatggaacag
    98101 gatacaagct aactactgct caatatttta cacctaatgg ggattatatc aatgaaaaag
    98161 gtataaagcc tactattgaa gagaaagatg aaaataaaca gttagatgta gcaactaagt
    98221 ggcttagaga acagattgat aaataggatt taatttttat aaacttatac tataaaataa
    98281 agaacattat aaaagagatg tctcaaaatg aactttttag ttcatgaggg agtctggaaa
    98341 tatttatgtg tattctttaa ataaaaattt attttttaag tgataattaa atttttacag
    98401 acagggctat ggttttaaaa atcatagcct tattttgata ttttttaaaa acatattgca
    98461 acccagttgt tccaaatatt atatcattta cttttaaaat atcgcaaact gcatattata
    98521 tattcattat aatataattt atctaactag aacctcagtt tactaattaa attagatgca
    98581 tagaataact tttttaaaca ttgaaaataa attaaactct aaacacattt aaatataaat
    98641 ttatatatca ttttgacttg gttaaacaat ttcatactta tcgatataaa aataggttat
    98701 aatataaatg ttcattatct tataacctat tttatataat ttattcctaa aacatgtgaa
    98761 tgttttttat gatagtttga agaaattata aaatcacttt ataattgaat attatatata
    98821 aattaattta aatatagaaa ggaaaatata tgtacaacaa tatcaaaaat attttaaaag
    98881 aaaatcatat aacgtttgaa gaatatgacc atgaacctat tttatcattt gaaaaagcta
    98941 aagaaataag agaaaaatta caatatactg gagtagaaag taaaagttta tttataaaag
    99001 ataggtctgg aaattactat atatttgtaa ccacagaagg aaaaaaatta gatccaaaaa
    99061 ctataaaaaa tgttttaggt ggaaaagtat ctatatgttc aaaagaagaa ttaacacaaa
    99121 aaacacaatg tttgcctgga tgtgtatctc cttttggata tgagaaaaat atctctcttg
    99181 taatagatca agatatattt aaccatgata aaataatctt ttcaccaggg ataccagaaa
    99241 agacatttat tattacagct agtggattta aaaaagtaat aaataatata aacaatacaa
    99301 cttataaata tatatatatt aatgaatttt aatcataatt gtaaattaga gaaaataaca
    99361 ttagaaatca tgcttaacta tagtgtaaat aaattatatt caacacaaaa gattgatact
    99421 attattacaa tagttactgt taagctcaaa ttcaatgtat tatgagttat tatttttaaa
    99481 ttttaattac aaaagcaggg tagttttaac tactctgctt tatatttaac ataaaatata
    99541 taaaatcaac aaaatgattt tagtctatct attagatatt cttcgctctc aatgcttaga
    99601 acttttagat atatacaata agtgctttca tttgtaaaaa tttctatagt attatcttgt
    99661 ttatttacac ctacaatatc tttaaaattg atatgatttt tagtattttt acatttgaaa
    99721 atatatctgt tatcaattaa aatctcatca ttagtaattg aaatataggg tttatctcat
    99781 gctttattaa aaatttatat gtttgttcaa gataaaaact tacaaataat aatagaaaag
    99841 ttactttaaa tgtacatatt atcgaaaata ttatcacaaa aatacttata atatatattt
    99901 gtttaaaata acctctatcg caatagttta ttaacgatat ggaaataaaa gtgttaaatc
    99961 agattttgga gaaataactt taaatatttc cagactcttt ttagacagcc tccataacct
   100021 tatattgaac ctatttatta actttgtact tacatatacc acttatataa gtttcgtata
   100081 tattaaagtc cttatctgtt actataaaat ctgcctccat accttgatgt atggagccac
   100141 aaacattatc aatattacaa cttaaagcag ggatatatgt agccattttt attgcatctt
   100201 ctaaagtggc tatgttccaa tcaactatat ttctcacagc cttgtccata gttaatacac
   100261 ttccagctaa actcccacta tttaatcttg caacactatt ttttacattt acattaaact
   100321 taccaagagt atattttcca tcctccatag caccagctct catacaatct gtaattaaag
   100381 ctatgttatt actagactta gcatccatca ttattttaac agctattggg cttacatgat
   100441 gaccatcaca aattaattca gcataagtat cttttagtac catagcagcc ccaaccattc
   100501 caggttctct atgatttaaa ggactcatcc cattatatgt atgtacaaac actttagcac
   100561 ctgaattaac gacttgttta acttgctcaa atgtagctga actatgacca agagaaactg
   100621 atatattatt tttagttgca tatcttgtta attctattga acctttacgt tctggagcaa
   100681 ttgctatttt tcttattaaa tttttcgatt ttttttgcca taattttaat atattgatgt
   100741 cagggtcttt aaaatatttt tcattttgag cgcccttata tttttctgta aaaaatggac
   100801 cttctaaata aatcccttgt atttttgcac cctcaactcg attgaagcta ttgcttatat
   100861 tttctacaga atcacttagt gtatctacag aatcagttaa agttgtaggt aggaaagatg
   100921 ttactccata ttttaataag ccttttgaaa ttgtgtttat tgcttcaaat gtattgtcca
   100981 tgacatctgc acctaaaaga ccgtgaatgt gagtatcaac taagccagga gcaatatatt
   101041 tacctgaaaa atctataaca ttatcagtaa cattaggtct ttcttgttga aattcaccga
   101101 atttgccatt aattatacta aggtaacctt tttctttgat tccatgtttc ataaaaaatt
   101161 tatctgcata aataaaactt ttcaaaataa cctccttata attatattat cattgtggca
   101221 ttgacgctta taatatcatt ctgttttctt gaaagttatt taacttacta tcttacatgt
   101281 cttactctat atacaaattt atcacttcta gcgacactca aagtaaattc aataactata
   101341 ttgtcatcat tatatgtggt acgaagtaat ttcagacaag gtgaatctcc tggtacttcc
   101401 aataacttag cttccttatc cgagattatt ccagctgaaa attcttcatc agcaacttta
   101461 ataatctcgc cataatcttc tctaaatatt tcatataaag gtttttgttc gattttttct
   101521 tttgtcaatc ctataaattc tttcatagga agatatgttc tttcaagcat cataggaagg
   101581 tcatcagcaa gtcttaaacg cattattttt atcatttttt caccaggagt tatacctaat
   101641 ttttcagaga aatactttgt actttctact acctcaaatg ataatacctt tgtacctggc
   101701 ttttttcctt gtgttctcat ataatctgta aaactataac tttccattaa gttttgagaa
   101761 ttttgactta gtgcagcaac aaaagttcct tttccatgtc ttttgtatat atatcccata
   101821 tgctctaact cagccatagc tagtctaact gtggttctac ttactccata ttcatcacaa
   101881 atttttcttt cggaaagcat tctatcgttt ggttccatct cattttcaat cttagttctt
   101941 aatatctcaa caagctggtc atatattggt cttttatcat ttctttttat cataaaaata
   102001 tagtcctttc taagtggtta ttaccacaat ttgattatag aatatagaat tatttatgtc
   102061 aatgaataaa gtttaatcaa aattcaataa gtaaggctat taatttatta taaaattatg
   102121 gtacattgac aaaacaagta aaataattta tattcaaatt ggtaataacc actttggata
   102181 tattatatga ggtatttttt attttacaga ttaatttatt gtttagaaaa gtaaaaatta
   102241 ataatgagga gaatctagta tgattacagt aataacattc aacccatcta tagatagaat
   102301 gtatagagtg aataatataa acataggtga ggtgcaaagg gtagtaagta agaatgcaac
   102361 tgctggaggt aaaggattaa acgtatctaa ggtatgtaaa attttaaaag aaaatccttt
   102421 agctatggga tttctaggcg gatttaatgg agaatttata aaaaatgaac ttagaaaact
   102481 agatatacaa aataaattta caaaaataga gcaggaaact agaaattgct taaacataat
   102541 tgaggacaat aaagttagta cagaattttt agaaaaagga ccaatagtag aaaaaagcga
   102601 tttagagaga tttgaaaatg atatagagga agtactaaaa aatactaaaa tactggtagc
   102661 ttctggtagt tattgtgaga atatgccgat agactattat gaaaagatag gaaatatatg
   102721 tagagcaaat aatataaagt ttatattaga tacatcagga gaagcattaa aaatagcttt
   102781 aaaatcaaaa ccatatttaa taaagccaaa tatagatgaa ataagacatt tattaggaat
   102841 aaatatagaa tcaagagagg aaattatctt gtcaggaaaa aaacttattg aaatgggtgc
   102901 agagaatgta tgtatatctt taggaaaaga tggtatggtg tatttaaacg aagataacgt
   102961 atattatgta aaagtaccag ttgtaaagtg tataaatact gtaggtagtg gagatagcac
   103021 agtggctgga tttagtgtag gtattttaag gggttataaa atagaaaatt tacttaaatt
   103081 tgcaaatgct tgtggtataa gtaatgcttt aaatatggaa actggatttg tagatttggg
   103141 agaaattgat aaatatcaag atttagttga agtaaaaaag ttaagttaaa tacatttaat
   103201 gggaatataa taaatttaat gttgttgtaa tagattttaa ttttaatata aaagatatag
   103261 tcttatataa aaataggtta gaaaaattca tttttaacct atttttataa taaatatcta
   103321 ttttactgaa tttataattt tctctagtaa tctttgagcc ttgatacact cttctccact
   103381 gatagctggt tttatattat tttctataca atcaataaaa tgatttgata tatcctcaaa
   103441 acccttttgt tttaatatat ttacccatgc accactttgc tttaaagtta ggtttccacc
   103501 ttcttctatt tccagtacat taagattctt aactctttga atcttaccct ttgaaagaat
   103561 ttcaacttgt tctaactttg ttccagaatc tctatgcata gaggtgttta tagagaaatt
   103621 tttaccttta agtttatgac ttacaaatat aagattctta ttgtctgtta aaaataaatc
   103681 ctctccacta atttcaacat cttcatttgc taaccataaa gcagtgtcaa taacatgtat
   103741 atagtcatct ataagagtac tgtcgaattt aacatttctt aaggaattta atccatgttt
   103801 acatatattg atagatacaa tttctgtagc attattttta atttctttgt acataggaca
   103861 gaatctacgg ttgaatccaa ccattaaatt taagtttttt ttcgtactta attcgataag
   103921 ttcttctcct tgacttactg ttgaagcaag aggtttgtct acatatacat gaacacctaa
   103981 atttaataat atttttataa tttcgtagtg tgtttctgta gagctatgta gaaaaataca
   104041 atcacatttt ttagctaggg attcaataga atcgaattgc atgattctat aatcactaca
   104101 gactttttcc cttttaactt tatttggagt aaaagctcct acaaactcaa atctctcaga
   104161 cttagttaat ataggtaaat atgccttttg agctatggag ccaagaccta tcattcccat
   104221 ttttatattt ttcataatac tttctcctaa ggtttttata tttacagaat tgattataat
   104281 tcagacacat aaatttgtaa actttgtatc aaaaaataaa tttaaagctt atataagtaa
   104341 attagcgaaa taagaaatat tgataaagta attttgtagg atatctataa aattgattga
   104401 tataaatatt ttatgtattg acaaaaaatt caaattaatt tatatttgga ttagtggtaa
   104461 ttaccacttt ggtctgaaca agtttttatc gtaaaataaa aatactaaag tatatagagt
   104521 atgattttat taaattttta aagataaact ataaaattaa ttaaaatcta tagtgtatat
   104581 tttatagtga gtttaagtag tactaaaaat ctaagcaaaa aattataaaa gagtatattt
   104641 ttttatagtt taaagtggtt ataacctcat taccaaatgt aaacgttaca agtatgaaag
   104701 gagaatgaaa atgtttaaat tagaagaaca aaaactaaaa gatttaggtg caataataac
   104761 aactaatgaa ataaaacaac agcctgaatt atggttagag acttatgaaa tatataaatc
   104821 taacaaagaa aaattaagta gattcataga tacaataagt aataatcatg ggcagtttag
   104881 agttatattt acaggtgctg gaacttcagc ttacatagga aattcaatac ttccttacct
   104941 taaaaataaa aatgacataa gaaaatacat atttgaagca atacctacta cggatatagt
   105001 ttcaaaccca tatgattact taaaaaaaga tataccaaca ttattaattt catttgcaag
   105061 aagtggaaat agtcctgaaa gtttggctgc tttaaattta gggaataaga ttgtagataa
   105121 tttttatcat ttagctataa cttgtaatcc agaaggagaa ctagctaaga tgactaaaaa
   105181 cgacgaaaat aattacttgt tattaatgcc atcaaaatca aatgatgaag gctttgccat
   105241 gacaggaagt ttttcgtgta tgatgttatc tgctatgtta atattcgata gtttagaaga
   105301 tgatgtagaa aagtcatata taaatgcaat agttgaaatg ggaagaaatg ttatagatag
   105361 aaaagatgaa atacatgagt taataaataa agattttgat agagttgtat atttaggttc
   105421 aggaggatta ggtggtttga cacaagaagc acaactaaaa cttttagaac ttacagcagg
   105481 aaaaatatct acagtgtatg attctcctat ggggtttaga cacggaccaa aatcatttat
   105541 tgatgaaaat acacttgtat ttgaatttgt atctaactgt ttatatacaa gaaaatatga
   105601 tttagatgtt ttagaggaga taaaaaggga taaaattgct aaattcactt gtgcagtgtc
   105661 agtagaaaat gaaaataact tctcaggaac aaagtttgag tttaaagaaa agtataataa
   105721 attaccagat gtgtatcttg caatgccata catattgttt gcacaaacta tagcattgtt
   105781 tgtatcggta aaggttggaa ataagccaga tacgccatca gctacaggaa cagtaaatcg
   105841 agtagtaaaa ggtgtaacaa tatatgaata ttaaaagata agattaaaat attataacta
   105901 aataatttgg gagggtatca atgtggcatt agtaacaaca acatcaatgc ttaaaaaggc
   105961 acaagatgaa gggtatgcag taggagcatt taatgtagaa aatatggaaa tggtaattgc
   106021 tgttatagaa gctgctgagg agttaaattc tccagtaata ttacaaacta ctccatctac
   106081 tgtaaaatat gcaggtcttg attattatct agcaaatgca aaggttgctg cagaaagagt
   106141 aaagatacct gtagcaatgc atctggacca tggttcaagt tttgaccttg caatgaaagc
   106201 tttaagaagt ggatatacat caataatgat agatggttct catgaaagct ttgaaaataa
   106261 tatatctata tctaaatcag tagtaaaagc atgtagtcct tctcttatac cagtggaagc
   106321 agaacttggg aaagttggtg gaaaagaaga tgatttagat ggcgggaata gtaatgatta
   106381 tacaaatcca aaagaggcaa aagagtttgt cgatagaaca ggaatatctt cattggctat
   106441 tgctataggt actgcacatg gattgtataa gggtgaacct aaaatagatt tagataggtt
   106501 atcagaaatt aaaaatgtag tttcaatacc tttagtattg catggaggtt caggaataca
   106561 tgatgatatt ataaaagaag ctataaaaag aggtattgca aaagttaact atgcaactga
   106621 attaagaatt gcatatagta aaggggttaa aaaagtttta gatgaagatt ctgaggttat
   106681 agaccctaaa aagtatggat tagcagggct tcaatcagta aaggattttg tgaaagaaaa
   106741 gattaaagtg tgtgggtctg taaatagagt ataaaaataa aatatcctaa atttatttta
   106801 gataagttta ggatatttgt tatatgaaaa atttatatta attatatgta aatggtgtat
   106861 ttttttcatt taattgatga aaaatatcag cttttattgg taaagtatta catatataat
   106921 taaaatatac taaaaattga actatatatt ttattattat aaaatattta tattaaattg
   106981 tggaattaaa atatactagg atataaaatt cttaaataaa aagaaaagat tgtttttata
   107041 aaaaatattt tttataccac ttaaaaaaac acaataataa cactgaggga ggtggggata
   107101 tgagagaacg cattattctt gaaacattaa aaaatagtag tggttatcta aacatagatt
   107161 attttgcaga taagttgggg gtatctactc gaactatcag aaatgaaata aaaaagatag
   107221 aaactataaa agaatgtaat ggttttaaat tagaatataa gtctaaatta ggatatattc
   107281 taaatattaa agaccaagat aaattcgagc attatctaag aaacttaccc tcagatttag
   107341 ttgaaaatcc agaacaacgg ttagagtcta taatagtaga acttttagta aatgaaggtt
   107401 ataaaactat agaacagtta agtaaaaaat ttctagtaag ttcatcccaa ataaaaaatg
   107461 atttaaaaaa gatagatgaa aagataaagg atacagaatt aaaactagag cgaaaggctc
   107521 attatggaat taaaatagaa ggttctataa aagaaattca aagtatattg gtggatagtt
   107581 attttagagg gaatagaaat ataacagagt acaggaataa gtttatagat aatttaaaat
   107641 tagctaatat tagaagtaca ataaaaaatg tacttaatga acatgattta gaagcaaatt
   107701 taacagaact tgaggaaata ttagcacaaa ttattatatt gtatataaga gttagtatga
   107761 gagtagcggg aaatgctagc gatttaaaat tatatacaga agatttaatt atagataaat
   107821 tattagataa aatttttaga gataaaaaat ataaccttaa ttatgatgaa aagtattatt
   107881 taaaggagct tataaaacta aagactaaag ataagaaagc cactataaag aatattgata
   107941 agaataaact tcaagatatt atgttcgaat tttttagaga gatagataaa aaatataact
   108001 ctaatttttt agaagataaa gagttcttta acttatttta cttacatatt gcatgtttaa
   108061 tagaacgtat aaagaagaac cacaagataa taaatccttt ttcagttaaa ataagtcaac
   108121 agtatccaac tgtttttaat ttatctattc aattttcaaa aatcatagaa aatgagtatc
   108181 atataaaaat aagtcaagat gaaatagggt ttatagctac tcacattgct gttccttttg
   108241 aaaagagaga agaagctaat tttaataaaa aatataaaat agcaataata tgctcttctg
   108301 gtggaggtag tgcatttttg ataaatttaa gacttaaaga aatttttcca aatgctgaga
   108361 taagaaattt ttcattacta gaagaaaaag ctgtaataga atttgcacca gatttgattt
   108421 tttcaataac aaatctttta tttgaaataa atgctccagt tatacttata aatgaaattt
   108481 tagacgaatt ggattattta gatattaaag aaagtgttag atttgcagac catataggaa
   108541 atatatcaag cccaaaacaa tatatattag gtctatttga taagaatcac tttaggtgta
   108601 taaaagataa agctaagtat aaggatatcc ttgatagtat gtcaaaatgt atagttgacg
   108661 agggcgcttg ttctccaacc tatcccaaag atgtatggga aagagaaagc tatttgagta
   108721 ctatttatac aaatggggtg gctatacctc atccaatcga gatgacagga aacaaaaata
   108781 taatatcagt agctttgata caaactgata ttatttatga aaatagggtg cctaaaatta
   108841 ttttcatgat ttcattaata aagggaaatt tagaacttca taagcaaata tctaaatatt
   108901 taagtaagat tatggcaaat aaggatatgg tagacatgct aaataagtca caatcttatg
   108961 aagagtttat gtataagtta aaaatctatc tgggaggtta gacatgaata tagagttttt
   109021 taagaggttg tcagaagcag atggtatagc atctaatgaa gaagaggtta gacatgtttt
   109081 attggaagaa ctaaaagctt atagtgataa aattatctgt gatgggctag ggagtatcat
   109141 cttttctaaa ataaaagatg agagtgcacc aaacgtaatg atttgtgctc atatggatga
   109201 agttggattt atggtgagaa gtatagacaa acttggtatg attcacttaa taacaatagg
   109261 aggagtaaaa cctcttgcac agtttgtaca aaaagttaga attacaacaa aagaagggaa
   109321 gaaaatccct gctgtcataa atgctacata taataatggt aaggctgaaa atatatatgc
   109381 agatattgga gcatatacag aagaagatgt atataaccta gggattaatg ttggggatat
   109441 ggtaacatat acaacaagct ttgaggaatt tactttacca gaccgattag tgggaaaggc
   109501 ttttgatgat aggataggat gttttgtgat gggagaagtt ttaaaagaac ttaggaaaga
   109561 aaatctaaat tgtaatattc actttgcggc tacaagtagt gaagaggttg gaataagggg
   109621 agcaaagaca tcaacacagt taataaatcc agatatagta tttgtaatag atgtagcatg
   109681 tgctaaaaat gagtttgtga gagactatac aaatcagaaa caaattgata aaggtgtaat
   109741 gctaatgcat agagatagga ctctagtccc tagtagaaaa atgatagatt atgtaatgga
   109801 aattgctgat aaaaataata taccacttca acatgatatg tttgaatcag gtgggactga
   109861 tggaggagaa gcacatctcg taaatgaagg gaaaccttgt gtagtaactt gtgtaccagt
   109921 tagatatggt cattgtgcat tttcaatagt aagtaataaa gatttagaga acattataag
   109981 attgtataca cagttaattt taaattttga tgaagaacaa tataaacata taagaaattt
   110041 tatctaaagg agaataagaa aatgtcaaca gaagtacaaa taatggaact tatatcaact
   110101 gcaggagaga gtaaatcgaa agcttttgag gctttaaaaa aagtgaagtc aaaagatttt
   110161 aaaggagcaa aattgttaat agaggaggct cgtaaaatag atattgaagc tcacaggata
   110221 caaacagaat taataactca agatttaaat gaagatgttg aaagtccagc aatgagtctt
   110281 ttaatggtac atgctcaaga ccactatatg acttctcagc tagcaaaaga cttgatagag
   110341 gctttgatat attgtcttga taagtaattg taatatagaa atagattatt tatgtaaaaa
   110401 ttcttttaaa agtttagatg cttttaagag ataataaaaa tacaaacttt aggaggaatt
   110461 attatgaaaa tattattatg ttgtgcaggt ggattttcta ctaatatgtt aatgcaaaat
   110521 atgaaaaagg tggtaaaaga gagtgctaaa ctcaatgaaa aagattttga gtttacagct
   110581 ataccagcag attcaataga aagtgaagtt gatgattggg atatagtact tataggtcct
   110641 caaatagctc acaaaataga cttcttaaaa ggaatattag agccaaaaaa taagcctttt
   110701 gcagtaatag ataaagatgt atatggaaaa atggatggag ctacagttat gaagttggca
   110761 ttaataactt ataagaaaca tcaattagct caaggataat aaaaataatg agggaaaagg
   110821 gagattagat atgttttcaa aatttgaagc atttatgaat agagtattta tgcctttagc
   110881 tcataaggtt gacaatcaac gtcaccttgg ttctataaag gctggtatgg ttgctatgac
   110941 accattcaca atattaggaa gtatatttgc aatacttcca gcacttccaa atatgcttgg
   111001 agaaaataat ccaataagca aattcatact taacaattca gcaatattgg atttaccagt
   111061 aagtctttcc ataggtttaa taggattata tgcttgtatg tgtattgctt ttaatctggg
   111121 gaactactat aaattatata taccaggttg tgttgcacta tcaacttttt cttttttatt
   111181 cctagtagca tcatttacac cagatggagc tttagaaata ggaaatttag gagctaaagg
   111241 gctatttaca ggtatgatag cagggcttgg ttctgtggag ttatataatt tttgtaataa
   111301 gaagaatatc acaataaaaa tgccagaaaa tgtacctgat tttgtatcta ggtcttttga
   111361 attaatacct actactataa tagtttgtgg aacttttata gttgctcgtt ttatttcatt
   111421 aaaagtattt ggagaattac ctccacagat acttactcaa tttttatctc cattagtagg
   111481 aagtatggat aacccatggt cagttcttgc acttaacttt gctatatgta ctatattctt
   111541 ttttggaata cattcatcag tatttagtcc tataactaga cctataatga ttacatttat
   111601 agctgaaaac atagcagcta tgcaagctgg agaaacaata cctcatttct ttacagcagg
   111661 agcttcaagt gcattctttg gatttacagg atgtggaatt agtataggtt gtgtaattgc
   111721 atgtatgtta tcaaaaaatg cttcctataa gaagattgga cgtgtatcat tattccctgc
   111781 attatttggg ataaatgaac caatattatt tggagcaccg ataatattaa atccaataat
   111841 gtttatacca catgtatttg gtggagctat aataggtaca ctaccaatgt tttttatgca
   111901 ctggggatgg ttagcaaagc cagtatttga ccctccatat gtaggggtat tcttagaagg
   111961 atttttaact aatggagatt ggcattctat attagcaaat gcattgcaat tagtattagc
   112021 agttttatta tattggccat tctttaaaat aatggaacgt caacaaaata ataaaaaaca
   112081 aaaagaagaa actaagaata tattctctaa agaagaagaa gacttattgg atgatttagg
   112141 attggatttc taatattttg ttatgaataa tacaatggag agattagtat ccttaatcta
   112201 taaaagaggt gttgacgctc ttttgattaa agcaaaaaat actaaaagat atataggagc
   112261 tttatcaggt agtggtgtat atgtgcttgt tactaaggat aaaaattatc aaattctaga
   112321 tggcagatat attgatgaag cagataaaaa aacgactggt ttcataaaaa ggattgtatc
   112381 tcaaggttct tatataccaa ctataattga gttattaaaa gaattaaata taaaaaagtt
   112441 agcaatagaa aaccaagcta tgagtataca agagtatctt tcactaaaaa atgaaggttt
   112501 tgaaatcaat ttaataacaa atgaattatg gaagctaagg gctataaaat ctaaagaaga
   112561 aattgaactt attaaaaagg cttgtgaaat tacagatgaa gtatttgatg aggttatttc
   112621 tgaaattaaa aaagatatga ctgagctaga agtatcagct ctaattcagt atcatgcatt
   112681 aaaaaaaggt gcaagtggaa tgtcttttga aacaatagtg gtatcaggag aaagaggtgc
   112741 aatgccacat ggaagaccta caaacaaaaa attgaaagtg aatgaagcta taacaataga
   112801 ttttggtgtt gtttatcaag ggtatcaatc agacatgact cgtacaatat ctataggtaa
   112861 acctcctaaa attattaaag agatatatga tgtagtattg gaagcacaat tatctgcaat
   112921 agagtcaata aaggaaggaa ctagggcaag tgatgttgac aaagtggcta gaaaaattat
   112981 agataaacat ggatttggcg aatattttaa tcatggactg ggtcatggta taggtcttgg
   113041 agatggtgaa gtccccactt taaatccaaa tagtgaagat atattagtgg aaggaatggt
   113101 aatgtcttgt gagccaggta tttatattcc aaatgtaggg ggagttagaa tagaagatga
   113161 cattgttata atagatggaa aaggtgttcc actcaataag acatccaaag agtttataat
   113221 attaggagag taaaattatg aaatataatt ttaataaagt attaaatcgt aaagaaggaa
   113281 attgtagaaa atggagcaac catgtgatta aagaaaaatt cggcttaaat gaagatgcaa
   113341 ttcctatgga tttagctgat atcgattttg agtgtgctcc tgctataaaa gaatctatct
   113401 taaaaagagc atcagtagga gattatagtt atacttttat aggagatgac ttctatgatg
   113461 cgattataaa ttggaataaa agaagatttg atgtatatat agaaaaggat tggataaaat
   113521 taacttttgg tactgtttca acccttcatt atatagtcca agcatatact aaagaaggag
   113581 agggtgtatt gataaataca cctgcttatg acccttttgc agaggctgta gtaaataata
   113641 atagaaagtt gtgttgtagc tcattaaaat tagataacaa tagatattat ttagatttag
   113701 aggatatgga aaatcaaatg aaatacgaga atataagatt gcttatattc tgtagtccac
   113761 aaaatccatc aggtcgtata tggacaaaag aagaactata tcaagtgtca gagttatgtt
   113821 taaagtataa tgtaattttg gtaagtgatg aaattcatag agatataata tttaaagatt
   113881 atagatttgt atctttatgg aatgctcatc cagaaattta taaaaatagt ataatctgtg
   113941 tatctcctaa taaaggcttc aacttaggtg gattaaaaac atcatatgta ttaataagag
   114001 atgtaaaaat tagggagact ttattagaaa gactaaaaag taattcaata acttctccaa
   114061 atgtatttgc aataccagca atagttgcag catataatga aagcgaagaa tggctagatg
   114121 ctatgactag ttatgtagag gagaattttg aaatagttta tgatttcttt gaaactaata
   114181 taccaaaagc taaagtgatg aagtcagact cttctttttt agcctggata gatgtaagag
   114241 aagtatttag aaatgaagaa gaatctaaag aattttttag acatgcaaac ttaactatgg
   114301 tagttggaag ttattttgtg aaagatggag atggatttat tcgtattaat gtggggtgtc
   114361 ctagagaaac attaaatgag gctctaaata gaatcaaaaa aacgtatata agtatgtatt
   114421 gttaaatcat aaaaaaagta tctatggttt atataaaaac acattattta gttatcaaat
   114481 attactggaa ttttgtattc cagtaatatt ttttgattaa ggaatattat tgaggaatat
   114541 taaataatat tatttcatac ccttatatta acttatataa aaatatttta ttattttggg
   114601 aacgggttag ctaaccttta tctagtgtat atttatattg taagaagcag taaaaacttt
   114661 tcctttacta agtttattaa taaacttctt atctttataa attttgttag aatttatact
   114721 atcagcaaga ccataccaag gttctataca taaaaaagga gcagtagaat tagtttcact
   114781 ataataagga gtccaaatac caactagagg gaaatcttcc atagatatag ttacatattt
   114841 actaccatca ttattacata tagatacttc atctatgttg gtgtatatca aagcatcatt
   114901 cttgaatact tctggattta actgtaagtt ttttaatttt ccaataggta ttatatcatc
   114961 tgtaaaagaa ccatttaaat tgattttttc tacatcattt ttacttttaa actcaaggta
   115021 gtgtttagaa aaatcatttt gttcgtaaaa aggaaggttg aatgcaggat gtccacctat
   115081 agaaaagaat atatctttag aatcagtatt ttttacaatc cattctacct caatactatt
   115141 atcatttaat gtatagttta tgattagctc aaaagaatat ggatacttct ttaaagtaga
   115201 ttcattatct gttaatttat aagttacaaa tgtatctcct ttatctacaa tctcaaagtc
   115261 catatctcta gcaaacccat gttgagtcat gctatataaa ttttcttcta ttattgtttc
   115321 attatcaaaa agtttaccta ctatagggaa caatataggt gattgtctac cccaatattt
   115381 tttattacca tcccaaagaa tgtttttgtc gtatttttta gaaaatattt tagttagttc
   115441 agcaccaaaa ctgcttgatt cgataattaa attttcattt tgtaatatat tcatttaaaa
   115501 tctcctttat tatattttat gagtatatta tactataaag tataaagatt attaaatttt
   115561 atttgatatt atatttgaaa ggtagatttt agtatatttt gaaaattttg ttttgaaaat
   115621 ttgggattat ttaagaaatt ttgtattata aatagaagga aatagataaa ttgtatagaa
   115681 taaaatatat taagataagt taataatgtt aaatgggaag tgagtttatg gaaaaaccaa
   115741 atacaaaagt tgttaacttt caagagtata aagacagaaa aaaccaaaga gaagtaaata
   115801 gagacgaact tttaaagctt ataaaaaaaa ttgtgacttc aaaataggga gttgttaaac
   115861 tccctatttt aatgggtttc ataataatta agacattctg agtccatcta tataatcttt
   115921 gaattgtgag aaatctgatt cactacttaa ttctatggtt tctgaacctt ccgtataaaa
   115981 attcttaaga tagatagtat aattattatc aacacaatca tgataaatac atctatatcc
   116041 atcttcatac aaacttttta acttagaaaa atcatccaca atatcatctc cttaaagttc
   116101 ttttaaatat atttttacaa aaagcatcta attgtatgca aattgacaat gtaaaataaa
   116161 ggaaatgaac ataaaatgta gaataatttt tatatgtatg taaaaataaa aagaaaaagt
   116221 tgaaattttt agaaaataag agtatttttt atctaaaaag agagtttaaa aaataaaaaa
   116281 atgttgggag gataaaaaat gagtttatta gaaagtatat caaaaaacat atattcccta
   116341 gataactctt ctattgaaaa aacaaagcag agattggata ggcttataca tccaactgga
   116401 agcttaggaa agatagaaga tatttgcatg caattagcag gaatatttgg caatgaaaat
   116461 tttgacacaa gtaaaaaggt tataattgct tttgcgggag accatggtgt atatgaagaa
   116521 ggcgtagcac ctgaccctca aaatataaca aaattacagt ttccaaattt ttcgaaaggt
   116581 ctatgtggag ttggagtaat aagtaaattt gtaggggcag atgttgtagc tgtagatgta
   116641 ggaataaact gtgatgaaaa actggatggg gtattagact acaagataag aaaagggaca
   116701 tcaaatatgg caaaaggtcc agctatgagt aaacaagaag caattagatg tttagagata
   116761 ggtattgaaa tagcagagca gtgtatagaa aaagattata aggttattgg tattggggag
   116821 atgggtatag caaatactac tccaagtaca gcaataatat ctgtaatttc agggtgtgac
   116881 ccgttagaag ttactggtat aggtgcaggt cttaagaaag aaagactaaa gcataaggct
   116941 gaagtaatta gaaaggctat tgaaattaat aatccaaatc caactgatgg agtagatatt
   117001 ttatctaaag taggagggtt tgaaataggc tcaatggcag gtgttatatt aggttgtagt
   117061 gctaatagga ttccagtagt aattgatggg tttatttctt atgcagcagc attaattgca
   117121 tataagataa atccaaaaac tagagaatat atgatagcat ctcatttatc agcagaatca
   117181 ggaactaaaa gagcattaga catattaaaa ttagaccctc tattaaatat ggatatgaga
   117241 ttaggtgagg gaagtggagc tgctttagca tttgatataa tagaagcttc aaactatact
   117301 tataaaaata tggcaacttt tgatgaaatt gacatgggaa gataaatata aaaatttaat
   117361 atgtaggagt gttttgatga gtaaaattat tctagtaaca ggaggagcta ggtcagggaa
   117421 gagtaacttt gcagaaaaac tatgttttga cagaaataat aatacagctt atatagcaac
   117481 ctctattcca tttgatgatg aaatgaaaga tagagtaaaa aaacatcaag agaatagacc
   117541 tagaaactgg aatacttatg aaatatatga agatatatat tccataatta aggagatata
   117601 taaagaacat gaaactgtta tactagattg tgtaacatta ttagtaaata atctaatgtt
   117661 tgaacacaat ctaaatatag aagaatctag tcaagaagaa ataaacaaat tagaacaata
   117721 cataaaagaa caagttgtca aacttattga agaaatagaa aaaacaaatc tatactttgt
   117781 atttgtaacg aatgagttag gtatgggaat tgttcctggg aataaactta gtagaattta
   117841 tgctgatatt gtaggtcgta taaatcaata tatagcttcg aaaagtaatg aagtttattt
   117901 tgtagttagt ggcatagcta tgaagataaa ggagtagtat gcaattatga aaagatttat
   117961 tttaatacta cagtttttga caaggatacc tataaaatta aatgtaggat ttgatgatga
   118021 attttataag tcaatagtat attttccact tgtaggtttt gtcataggta tattatccta
   118081 tttaatagga tggatttcta tgcttttatt tgaaccattt atagcttcta taataataac
   118141 tctagctggt gtcttaatta ctggaggact tcatatagat ggattaggag atacatttga
   118201 tgcaatatat agttataggg ataaagaaaa gatgcttgaa ataatgaaag attcaagatt
   118261 aggtacaaat tcacttctag caattatgtt tgtactttta ttaaaggttg gattcgttta
   118321 cgatataata agtaataatt cattgtgggt tataattttt atgccaatga ttgcaaggtt
   118381 aggagtaatg ttattgacat ataaaactgt gacaccaaga gaaaaaggaa tgggaaattt
   118441 atttatagga aaattaacta caagtatgtt aataactgct ataatataca cattattgat
   118501 agttgctctt attactaaat ttatattttt attacctaat atagtgttga ttaaagtatt
   118561 aggttcgatt atagtggttt ttgtatttat aatattattc aaaaaacata tttataaaaa
   118621 aattgacgga gtaacaggag atatattagg ctgtggaata gaactttcag agcttgtata
   118681 tttaatttac atatatttgt taatttttat gtttttttaa agtaaaaagt ggtgataata
   118741 tgataagatt aatattaata agacatgcac tgacaaatga taataaaaaa ggaagattat
   118801 caggccatat aaatagttgt attagtgaag agggcaaact acaaataaat aaaattacca
   118861 gatatctgag taatgaaaac atagataagg tttatacaac accatctaca cgtactaaag
   118921 atacagtaga aaaaatatca aaattgaaat tattagaaat agaagaaaaa gaagctttaa
   118981 gagaaattag ttttggagac tttgaaggaa gaacttttga agaaattaaa atcaaatatc
   119041 caaatgagtt tgaaaaaatg ataaaagaag gtaacaacta tagatatcca aatggagaaa
   119101 gtttgataga ctcttataaa agagtggcaa aagaaattga taatataatt ttagaaaatg
   119161 atagtaattt agatacaaag acaatactta tatgttctca tgcaggaaca ataagaaata
   119221 taataacaca tttgatttct ggtagttata agtatcactg gaactttaaa attgataatg
   119281 catctattac agttttagaa attgatggtg gatttgctgt aatagataaa atgaatttta
   119341 cagacttcat ataatttaat caaaaccaaa cattacaatc tgtgtttgta atatatctgt
   119401 aaaattagca atgaaaatag aatattagat taaaattagg ttcttaatta gatgttaaaa
   119461 gggaaaaagg ttagatgcct ttgcagcccc cgctactgtg aaaccaacga aactataaat
   119521 accactgtca gtttgatggg aaggttatag aagtaggatg aagttaagcc aggatacctg
   119581 cctaatttaa tttaaaacaa gaggtcttcg gggtgaaaga tttttaatta atatatataa
   119641 aagtcctatc tttagaagta ttaggacttt ttttaatttg ttttttagta aattttaaca
   119701 aggagggatg gaaagtgggg aaaaaaataa tgctacaagg aacagcttca aatgtaggta
   119761 aaagtgtctt agtagcaggt ttgtgtagaa tatttaagca agatggttat actgttgctc
   119821 cttttaagtc acaaaatatg gctttaaatt cttttataac taaagaagga ttagaaatgg
   119881 gaagagcaca agtatttcaa gcagaggctg cgaaaataga gccaatagct gatatgaatc
   119941 cagttttatt aaaaccttct ggaaataata aaagtcaagt tattgtaaga ggtaaagttg
   120001 taggagaaat gccttcttct aagtatcatg attataaatt ggagttagta gatgtgttga
   120061 aggaaacatt taatagctta aattcaaggt atgatattgt agttatggaa ggggcaggaa
   120121 gtaatgcaga gataaactta aaagatagag atatctctaa tatgggtatg gcagaaatag
   120181 ctgatgcacc tgtaataata gtcggagata ttgatagagg aggcgtattt gcctcattag
   120241 caggaacaat gcttttatta aatgaagatg agaaaagaag agtaaaaggt gtaataatca
   120301 ataaattcag aggaaaaaaa gagcttttac aagatggtgt aaagatgcta gaagacatca
   120361 taaaagtacc tgttatagga gtagtacctt atacagatat aaagatagaa gatgaagaca
   120421 gtgtaactac gagatttaag aaaaaaatga ataaaagtga tatacacata gaaataatta
   120481 gaactccaca tatgtcaaat tttacagatt ttaatatatt tgagacacaa gaagatgtaa
   120541 gtattagata tgtagactat ggagaatctt taggaaatcc agatatatta ataatacctg
   120601 gaactaaaag tactatagac gatttaacat atataagaaa aagtggtctt gaatcgcaaa
   120661 tcaaaaattt acatagtcaa ggtaaattga tatttgggat atgtggtgga taccaaatgt
   120721 taggtaaaaa attaaaagac ccttatcatg ttgaaagtga aattgaagaa gttgatggaa
   120781 taggtctttt agatacagaa acaacgtttg agaaagaaaa gactacaaca caagtagaag
   120841 ctactattgt tgaatgtatt agtgaataca tgaataacct taagggaaaa aaagtaaaag
   120901 gttatgaaat tcatatggga attacaaagc gaggtaatga tgtaagaagt ttagatttaa
   120961 taactaaaaa acttgataaa gaagtgaatt atactgaggg aagtgtaaat aaagagggga
   121021 atgtaattgg gacttatctt catggaatat ttgatgaaat aagctttaca agagcaattt
   121081 taaacaatat aagaaagaaa aaaggtttag gagaattaga aagcaaagta aactctttta
   121141 atgaatttaa ggataaagag tatgataagt tggctgattt tttaagagaa catttagata
   121201 tagagaaaat atatgagatt atgaaataat gatgaccttt atttataatt taggtaggag
   121261 gtgtattatg aaaaaaattt taattgcggg tactaatagt ggagtaggta aaacaacaat
   121321 atcattagga ataatgcaag ctttggttaa gagaaatatg aaagtacagc catataaagt
   121381 agggccagac tatatagacc cttcatatca cacttttata actggaagac attctagaaa
   121441 tttagattct tatatgttag atgatgaaaa aataaagtat atagtaaata agtcctcaaa
   121501 agatgcagat atttcagtaa tagaaggtgt tatgggctta tatgatggct ttggaataga
   121561 tttagataat tgtacaagtt cacatacttc aaaggtatta aagtcacctg ttatattagt
   121621 tataaatggt aaatctatgg cagcatctag tgctgctatg gtacttggat ataaggaact
   121681 agataaagat gtaaatataa agggtgttat agtaaataat gtaaagacta atagccatta
   121741 tcaaataatt aagagttcta tagaaaaata ttgtaatgtt gaagtattgg ggtattttcc
   121801 tccaaataac aaattctctt tggaatctcg acatctagga ttagttccta gtgtagaaat
   121861 gaaatcacta agggaaaaat tttatacctt agcagatgaa attgaacact atatagatat
   121921 tgacagaata attgaaatat cagaaagcga tgaatttgag agtgattttg attttcaaac
   121981 tttaatagaa aataataaaa taaaagaaca tgttaataat aaatcaatag ctatagcata
   122041 tgataaagca ttcaattttt attatagaga aaatatagag cttttagagg aacttggttt
   122101 agaaataaac tattttagcc ctcttgaaga tgtatcagtg ccaaatgcag attatattta
   122161 tattggagga ggttttccag aaatatttgg aaaagaatta gaagcaaatg agtcaatgag
   122221 aacttccata ttagaagcac ataacaataa tatacctatt tatgcagaat gtggaggact
   122281 gatgtaccta ggtgagaaac tattgaatca agaagaacaa gaatttaata tggttggaat
   122341 atttagtgga attagtaaga tgacatcttc tttaaaaaga tttgggtact gtattggtgt
   122401 agccaaggaa aatactcttt tatctaaaaa aggggaatct attaaagggc atgagtttca
   122461 tcattcaata tttgaaagtg atgaaaaatg tgtatattca atgagaaaag aaagagatgg
   122521 aaatatagta gaagagtggg atggtggtta tagtaaagga aacactttgg ctacatatct
   122581 tcatactcat ttttataata acttaaattg tatagaaaat tttttgaaaa aaggaaatga
   122641 ataaatgagt attttatcta tttatatagg atatgtgaca gacttaattg taggagaccc
   122701 atattctttt cctcatccag tgagatttat tggtaaactt ataaatttta ctcaaggtat
   122761 aataagaaag gtctctaaaa atgataggca gttaaaattg gggggattta tattatggtt
   122821 tataaccgtt ggaataacat atttaacaac ttatgctata gtgaagttat ttagttttaa
   122881 tatattattg agtattgtag tgaatagttt tataatttat acaacactag ccacaaaatg
   122941 tttaaaagac gaagcattaa aaatttataa tgtattaaaa actgaagata tagaaaaatc
   123001 taggattcag ctatcttata tagtaggtag ggatactact aatttaagtg aacctgaaat
   123061 aataagagca actgtagaaa ctgttgcaga aaatactgta gatggtataa ttgcgcctat
   123121 gttttatgca tttattggag gagcaccact tgctatggcc tataaagcta tcaatacatt
   123181 ggactcaaca gttggatata aaaataaaaa gtataaagat attggttttg catctgctaa
   123241 gattgatgat atagccaatt atataccagc tagaatatct gtcattctta tgacaattgg
   123301 aagtttcttt ttaaattata actataggaa ctgttttaaa atctctatta gagatagaaa
   123361 gaatcataaa agtccaaatt gtgctttttc agaaggtgca gtatctggtg ctctaggaat
   123421 acaactagga ggtaccaacg tttattttgg ggaaaaagta tataagccaa caatagggga
   123481 taagcttagg gagatagata aagaagatat aattaaaact aataaaatta tgtatgcatc
   123541 ttcatttgta tctatgttgg tatttacact aatatatgtg ttatgtagga tgattttaat
   123601 taacttaatt atataaatta ttgtttgtta acttaagggg gacatagatg aaggatttag
   123661 ggcatggtgc caatgtagat gaaatggcaa gattatatgg gaaaaaccca aaagaaataa
   123721 ttgattttag ttcaaacata aatccaaatg tattaccaaa tttagagaga tacattttaa
   123781 aaggattaga agagtgtagg aattatccag atataaatta tacaaacttg agagaaaata
   123841 tatcaaaata tatagatata aatccagact ttataatacc tggcaatggt gcaacagaag
   123901 tgatttattt gcttatgaag agtattaaaa aaaaattggc tataataaat ccgacttttt
   123961 cagagtatag aagaagtgct gagttaaata atttagatat tatagattta gagttagatt
   124021 tagaaaataa ctttaaactt aatatagata taataaaaga aaatataaaa agatttgata
   124081 gtttatttat atgtaatcct aataatccga gtggtaatgt ccaagattta aaggaacttg
   124141 ttcatttact agataaacat aataaggtat taataattga tgaaactttc atggaatttg
   124201 ttgaagatga aagtaaatat agtttggtta aatatataga atcaaataaa aatatattta
   124261 taattaaagc tgtgactaag ttttttggta tgcctggttt aaggctagga tatggtctta
   124321 caagcaacac tgaaattatg aacaaaattt atgaacacaa agagccatgg actatcaatt
   124381 cttttgcaga tatactatcc aattttattt ttgaagataa agagtatatt aaaaatagta
   124441 aagaatatta catagaagaa agagaatata tgttacaaga gttgagaaac ataagaaata
   124501 taaaggtcta tgatacagat gctaatttta tcttgataaa aatatataaa aaaacaacta
   124561 aagaattgaa aaaagatttg tttaagcaag gaaacatatt agttagagat gcgtctaatt
   124621 ttataggatt agatgatagt tttataagag tggctataaa atctcatgaa gataacaaaa
   124681 ttcttataga aaatatgaaa aatttattgg gtgattaaaa tgaaatctta tggaatatgc
   124741 ccagcatctt gtggagaatt tgtacaaggt ataattgatg atgaagaata tttatgttca
   124801 tatgcaatag atatgtattc taaagtgtat attgaagaaa aattagtaga tataaattta
   124861 gggagatata agtcaaggtt agcaattgaa aaggtatttg aaaaatttaa tttacctaaa
   124921 aaatatacta aaaatatttc tttaaatata aatagtaaaa tacctgttgg aaaaggaatg
   124981 gcaagttcaa ctgctgatat aggagctact ataaaggcaa cattatcatt gatagataaa
   125041 gatttaagta gcgaggagat ttctaaatta gcagcagaaa tagaaccaac agattctata
   125101 tttatagata aaaatagtat atttaatcct ctaaatggaa ctgttataaa atacctagga
   125161 aatctgacca atgcgaaagt tgtaatactt gaaccaaaca aagtactaga tactatgaaa
   125221 attagattga ggcaagatta taataaatta aaagtagaga ataaagaagt aataaaaaaa
   125281 tcatttgctc ttttagaaga aggattgaaa aaaaataatt tatctctagt tggagaggct
   125341 tgtactttga gtagcttagc aaatgagaat atagaaaaaa aagagtattt aaatgaaata
   125401 ataaaaatat caaaaaaata tggagcatat ggagtaaata ttgctcacag tggaactgta
   125461 gtaggtattt taattgataa gtttatgaat gataaaaaga tgatagatgc cttatgtgaa
   125521 tctaacataa attctgtcta taataaaatt tatacacaaa acataattaa tggaggaatt
   125581 aagggggaaa tagaatggaa tacataaaga atcctatgaa aatagaagaa aaaagttttg
   125641 aattgataca agaaataata gacgaaatta gaccagatta taaatttaag aataatatcg
   125701 aagaaaaaat aataaaaaga gctatacata ctactgctga ttttgattac ttagatatat
   125761 taaaaatatc agaagaagca gttgatagta taatagatgc attaaaaaat aatgcaagta
   125821 tttatactga tacaaatatg gctcttagtg gtataaataa aagaaagtta gaatcattag
   125881 gatgtaagta taaatgttta gtggcagatg atgaaactgt aaaattagct aaagaaaaag
   125941 gaattactcg ttctatggca gcagtagaaa ttgcagctaa agaagaagga agaaaaatat
   126001 tcgttttagg taatgctcca acagctttat ataaagttat ggagatgaaa tcagaaggta
   126061 gattagattt agatgcagtt ataggagttc ctgtaggttt tgtaggagca caagaatcaa
   126121 aagatgaagt tgaaaaaaca gatataccat atataatttc taaaggtaga aaaggtggca
   126181 gtaatttagc agcagcaata gtaaatgcta tattatatac tatgtaggta cctatatgga
   126241 agaatatgta tatatagatg gaaaaaaata tagaagagga tatactacag gttcatgtgc
   126301 aacaggtgca tctaaggctg ctgtatatat gttgattaca aaaaatagaa ttaatactat
   126361 aaatatagat actcctaagg ggataccatt actactaaaa gttgataata taaatatttc
   126421 tgatacattt gtggaatgtt ccataaaaaa agatggtgga gatgatatag atgcaactca
   126481 taccatggat atttatgcaa gagctgaaat tgtagctaaa aatgataaga acaaagggta
   126541 tcttactcta aaggatatag atagtttaag caccaatagt gagtgtaaaa gtgagctcta
   126601 taagtttatt agggtttatg gcggaactgg tattggtgtg gttacgaaaa aagggcttag
   126661 tgtggatgtt ggtaagcctg ctataaatcc gactccactt aaaatgataa atcatgaaat
   126721 aagaaagctt ataggagata attttgaatc tatacttgga aatgataaag ttttaaaaat
   126781 aacaatcttt gctccacaag gagaaactgt agcaaaaaaa acatttaatc caagattagg
   126841 tatagttgga ggaatatcta taataggtac aactgggatt gttgaaccca tgagtgatga
   126901 tggttggaag aagtctctat ctatagaact tcagatgaaa aaagaacaag gcttagataa
   126961 aataatattg gttccaggaa atcatggaga acagtttata agagaaaaat taaacttaga
   127021 tattaagtat gtagttaggg taagtaattt tataggctat atgattaaag aagctcaaag
   127081 aataggatat aaaaaaatct taatggcagg ccatataggt aaatttataa aagtatctgc
   127141 tggtattttt aatactcata gtaaggtagc agatgctaga agtgagatat tagtggcaaa
   127201 cttagcttta atgggagcta gatacgaatt tttaaataaa ataaatcaat gcgtaactac
   127261 tgaagaagct gtagagctaa taaataatag tgaatataga gaagtatata atatattaag
   127321 taataaatgt agggagagag taaagcaata cttgaatgaa gattcagatg atattgatgt
   127381 ggaagtaatc atattttcaa tggataagtc tttattaggt aaatcggata atacagatga
   127441 tttagtggag gtctttatat gataaacata ataggtctag gacctggtaa cttagactat
   127501 ataacaaaaa aaggtgaaaa tttaatttcc acttctgatg tattaattgg tggtaaaaga
   127561 aatttagagt ctataaaaaa ttttgaagga gaaaaaatag ttctggattc taatttaaga
   127621 gaaattatag agtacataaa taacaataaa gaaaagcaaa tatcaataat agcatctggg
   127681 gacccattaa tatatgggat aggtagatat ctatctaaaa atattgataa taagatgtta
   127741 aacatggttt ctgggattag ttcattacag tacatatttt caaaaatata tgtagatatg
   127801 aatgatgtat atattacaag tagtcatggc aaagtaccag attttgatta catattatca
   127861 cataaaaaag tatgtatggt tacagattca aagataggac caaaacaaat aagtagagaa
   127921 ataatagata gaaatctaaa taaaattatt gttgtaggag aaaatctgtc atatgacaat
   127981 gaaaaaataa caatagcaaa accagaagag ataataagaa tggacaattt tgatatgaat
   128041 gttgtggtga ttttagatga ggaatagtga atttataaca ggtaaagttc caattactaa
   128101 ggaagaggtt agagcaatat caataagtaa gttaaattta gtaaatgcta aaaacctcat
   128161 agacataggg gctggtacag gaagtgtaag tgttgaagct gcatataatt atcctaattt
   128221 aaaggttata tctatagaga aaaatgatga tgctatagag cttatagaga aaaataaaaa
   128281 aaaattcaac ttaaaaaata tagaagtgat aaaaggatat gctccaatta atctagggtt
   128341 aaatgttaaa gttgagtcta tttttcttgg gggaacagga aataatctgg aagaaataat
   128401 agaatggtct aaaaaaaatc tcgttacagg aggaagactt gtagctaatt ttataataat
   128461 agatacattt aatcaaactt taaaactgct taaaaagcat ggatttaaag aaatagatgt
   128521 atgtgttttg aatgtttcta aactagagaa actaggaaaa ggtgaatatt ttaaaccact
   128581 aaatcctata tatataatat cttgtgaaaa aggggaaaat gatgatgaat aaagtacatt
   128641 ttgtaggagc aggacctgga gataaagagc tgataacatt aaaaggatac aaattattaa
   128701 gtaatgcaga tgtagtgata tatgcaggtt cacttgttaa tcctgaactt ttggaatact
   128761 gtaaagaaga ttgccaaata cataatagtg cacatatgga tttacaagag ataatagatg
   128821 ttatgagaga aggtatagaa aataataaat ctgttgtaag actgcaaaca ggtgattttt
   128881 ctatatatgg ttcaattaga gaacaagtgg aagatttaaa taaattgaat atagattatg
   128941 actgtactcc aggagtaagt tcttttttag gggcagcatc atctttaggg gttgaatata
   129001 cagttccaga aatttctcaa agtgtaatta taacaagaat ggaaggcaga actccggttc
   129061 cagagaaaga atcaatacaa tcatatgcta agcatcagac atctatggta atatttttat
   129121 ctgttcaaga aattgagaaa gttgtgtcta aattactgga aggtggatat ccaaaagata
   129181 ctcctatagc agttatatac aaagcaactt gggcagatga aaaaatagtt aaaggaactt
   129241 taagtgatat agctgtaaaa gttaaagaaa acaacataaa taagactgct ttaataatgg
   129301 ttgggagatt tttaggagaa gagtataata attcaaagtt atatgataag gatttcaaac
   129361 atgaatatag agggtaatat tgctataatc tgtattacag aaaatggaaa aaaattagct
   129421 ctaaagataa attctctagt aaataactgt gttatatatc atgtaaaaaa taaaaaaagt
   129481 aatttagttg ttgaagaaac atgtgtgcat acagttcaaa agaagttaag tgattttgta
   129541 ggagaaatat ttagcaaatt tgattacata gtatttataa tggctacagg tatagttgta
   129601 cgaagtatag caccatacat aataagtaag tttagtgacc ctgcaatttt ggtaatggat
   129661 gaaaaaggca aaaacgtaat aagtttattg agtggtcata ttggaggggc aaacagcttg
   129721 acacagtaca taagtagtct tattgatgct aatccagtaa taacaacagc tactgatata
   129781 aatcaaaaag cttccttaga tatgatagca aaaaaactaa atgcacatat tgataatttt
   129841 agagaaagtg taaaagaagt aaattctatg ctagtgaata ataaatgtgt tggattatat
   129901 attgatgaag gatatcaagt tgatactagg ggatttaaac ttatagaaag taaggatgag
   129961 ttaagagata gtttttcaaa cacatatata gaaaaattag ttgtagtaag caataaaata
   130021 aattgtattg aagatattga gaatttaaac ctagataata aatttgaaca ttgctatagt
   130081 accaaaaaaa taataaaggt aattccaaga gatatagtga taggaattgg ttgtagaaga
   130141 aacacagata gtgaactgat gtataattca cttgaagagt ttcttaataa acaaaatata
   130201 gatattagag caataaacac agttggaagt atagaactga aaaaagacga aaaagcaata
   130261 attgaattat caaaaatatt gaaggtgcca tttaaaacat tttcagtaga tgaaatatct
   130321 aaggttgata atctttttga taaatctgat tttgttaaaa aaaatgtggg cgtgtattca
   130381 gtagcagaac ctgtagcata tcttttgagc aaaggtaatt tgttagttga aaaacataaa
   130441 tataaaggaa taactttttc agtggggaga ataaaaatat gatatacgtt gtaggaattg
   130501 gaccaggaag taaagataca atgactttag aagcaataaa agcaatagaa gattctgagg
   130561 ctattgttgg atataagact tatataaaac taatagaaga atttatacaa gataaagaaa
   130621 taatccaaaa tggtatgagg caagaagttg atagatgtaa acaagcagta gaggaagcaa
   130681 aaaaaggaaa aaaagtagca gttgtaagca gtggtgatgc tggaatatat gggatggcag
   130741 gtcttatttt agaattaata tctaaagaag atgaagatat aaaagtaaag gtaattccag
   130801 gtgttactgc aagtattggt gcagcagcta tacttggagc tcctattatg catgatttct
   130861 gtcatataag tttgagtgat ttaatgactc cgtgggaagt aattgaaaaa agattgagat
   130921 tggccgctga agccgatttt gtaatttgtt tgtataatcc aagaagtaag ggaagaagtg
   130981 aacatctaag caaagcattt aaaataatgg gtgagtttaa aggtggagat acacctgttg
   131041 gagtggtaaa agatgtaggt agagaaaaag aagaaaagtt tgtatgtact tttgaaaata
   131101 tggactttga aaaagtcgat atgactacaa tggttataat aggaaataag tctacctata
   131161 ttaatggtga attgatgata actccaagag gttatacagt atgattttaa ttttaggagg
   131221 aacttcagat agtttatcta tatgtgataa gataaatgaa ctgaaaaatc aaccatatat
   131281 cctttcagtt actacagatt atggaaggga acttgcacaa caacatgcag agaatgtaat
   131341 tttaggtaag cttggaaaag aagatatgct aaaatttata aaagataata atatagtaaa
   131401 aataatagat gccactcatc cttatgcagt tgaagtatcc aaaactgcta ttacttgtgc
   131461 aaaactattg aatatagatt atataaggtt tgagagaaaa tctttaattg aagaaataga
   131521 ttatgataat aaatttatag tagatacaat tgaagaagcc tgtgaaatag caaataaaat
   131581 agggacaaat atattcatag gaacaggaag taaaaatttg aacagattta tagaggaaat
   131641 aagtgataaa aatttagttg ttagagttct tccaacgagt gaagtcatat taagttgtga
   131701 aaaattaggt ttaagtgcag ataatatagt agctatgaaa ggtccattta gccagtatat
   131761 aaatgaagaa acatataaac attacaatat agatttagtc ataacaaaag aaagtggaat
   131821 agctggtggg ttcttagaga aggtaaatgc atgtaaaact ttcaatatac cagtaataat
   131881 tataaaaaga gaatcgatta actacgaaaa tgtatttaat gacataaata aaattaaaga
   131941 catacttgtg taatttttag gaggagaata tatgaagaaa gccttattag tagtgagttt
   132001 tggtacaagc tatcatgaaa cgagagaaaa gacaatagat atatgtgaag ataaaataaa
   132061 aaattcgtta aaaagccatg atttttttag agcttataca tcaaatatga taataaataa
   132121 aataaaaaaa agggatggaa tagaaataga taatccaata caggctttag ataaaatata
   132181 tgaacaagga tatgatgaag taataatcca aacacttcat attatatgtg gcgaagaatt
   132241 taacaaatta aaagaacaag tagatggata ttcttctaaa ttcaaaaaga ttgtattagg
   132301 aagacctttg cttacacata ttgaagatta tcaggaagct gtagaggcaa ttaagcatca
   132361 aattcctcat atggaaagta atgaagcagt agtatttatg ggacatggaa cacttcatga
   132421 atcacattca gcgtatccag cattggaata catgcttagg gataatggaa taaatgctta
   132481 tgttggtaca gttgaagggt atccagaaat agaacatgta ataagaagat taaaagaagg
   132541 aaatataaaa actgtaaatt tgatgccatt tatgttagtt gcaggagacc atgctataaa
   132601 tgatatggca ggagatgaag aagattcttg gaaaacaata ttagaagaaa atggatttaa
   132661 cgtaagagtt catttaaaag gactaggaga aaattcttat atacaagata aatttgttcg
   132721 tcatgctgta aaatgtgcag agaatgcgaa gttctatggt ataggagcag ggccaggaga
   132781 tggttcttta cttacgataa aagcggttaa tactttaaag aaactggata ttctatacac
   132841 tccagaatca aaaaagggtg gagatagtct agctttatca atagttagtg aatatttacc
   132901 tgaatcagtg gaaataaagt ctaggcattt cccaatgagt tttgatggga atgaaaaaag
   132961 tttagcttgg gacaatgtgg cacaagaaat tatatcagat gttaatgatg gtaaaaatgt
   133021 aggatttgtt acattaggag accctatgat ttatagtaca tatgtatata taatgaaaag
   133081 aatattagga gaggtagaag tcgaaactat accaggaatt tcatcatttt ccaatatagc
   133141 atctaatcag aattttccat tagtcatgga taaagaagct ttagtggtaa ttccttgtac
   133201 tatggaagat gataagatag agtatgcttt gcaaaattat aattcaatag tattgatgaa
   133261 agtatataaa aattttaaag aaataataaa aaaattagaa aagtatgatt taatagaaca
   133321 tgctatttta gtaagtaatt cttcccaaga aagcgaaaat gtgtttacag atttaaaaga
   133381 agcgcacctt gaagataaga tatcttattt ttctactata ctagtaaata aagataataa
   133441 aataaaatag gtgaaagcaa tatttaaagg agacttaata tgaatatagt ggttggaact
   133501 aggggtagta atctagcgct tatacaaaca gaatgggtaa taaatgaatt aaaaaagaag
   133561 tatccagaaa ttagttttga gattaaaatc ataaagacaa aaggagattt aattcaaaat
   133621 gtttcactgg ataaaatagg tgataaagga ttgtttgtca aagaaataga gcaacaatta
   133681 ttagatggaa aaatagacat agcagtacat agtatgaaag atatgccttc ttatttagca
   133741 gatggactaa aatttgctca tacgcctaag agagaagacc caagagatgt tctaatactt
   133801 agagaaggat ataaaaattt agatgattta cctcatggag cagtaatagg aacaggaagt
   133861 aaaagaagga agtttcaatt attgaaacaa agacctgatt taaatatagt acaagttaga
   133921 ggtaatgtgg aaactaggat acgaaaaata aaagatgaaa acatgcatgg tattgtgttg
   133981 gcagcatcag gaataattag agctaatttg caagataaaa taagttctta tttacctgtt
   134041 gatgttgtta ttccagcacc tgcccaagga gctttagcta tagaaattag aagcaatgat
   134101 agtgcgatag agggaatagt aaattcactg aaggatgaga atacagaaat ccaaatattg
   134161 gctgaaagag gttttttaga tggtgtaaat ggaagttgtc atattccaat ggcagcttat
   134221 tgtgaaataa tccaagataa aatacatctt actggcttat atggagattc agaaggaaaa
   134281 aaagtagtaa tcaagtctat agatggagat atttcttctc ctagagagtt aggtttaaag
   134341 ttagctaaac ttgtattgaa ggagtatgag aattatgaag ggtaaggttt acttagtagg
   134401 ggcaggacca ggtgattata aactcatgac tttaaaaggt ttagagtgta taagaaaatc
   134461 ggatgtaata gtatatgata gattagcaaa tagtagttat ttaagagaag ctaagcctga
   134521 ttgtgaactt atatatgtag gcaaggcatc aagtaatcat attttgccac aagaagatat
   134581 aaatagaatt atagcagaaa aagctaaaga aggaaaaatt gtaactcgtc ttaaaggagg
   134641 agacccttat gtatttggca gagggggaga agaagcagag actttagtag atgaaggtat
   134701 agaatttgaa gtagttccag gtataacttc tgctatagga ggtttatgtt atgcgggtat
   134761 tcctataaca catagagacc atgcttcgtc atttcatgta ataacaggtc atttgaaggg
   134821 tgatgatagt ggagaactaa actggaatgc tcttgcaaat aacaaaggta ctcttgtgtt
   134881 tttgatggga atttcaaacc tagagaaaat aagtgaaaac ttaatgaaag aaggaaaaga
   134941 taaggataca cctgttgctc ttataagttg ggcaactaga tataatcaaa gagttgttac
   135001 atctacactt gaaaatgttt atgaaactgc tattaaagaa gaagtaaaac cgccaactct
   135061 tatagtagtt gggagtgttg taggacttag agaaaagttg aacttctttg aaagtaagcc
   135121 tttatttgga aaaagtattg ctgtaactag gtctagaaat caaaatagtg tattggtaga
   135181 aaaaataatg gatttaggtg gaaatcctat agaaatacct actattaagg tagaaaaaat
   135241 acaaaataat attaacttag aaaatgaaat aaaaaatata aataagtata attatctaat
   135301 actaactagt aaaaatgccg tagaaatctt ctttgaaaag atatatgaaa tgaattttga
   135361 tttaaggata ttatctaatt taaaggtatg tgctataggt tctgctacat caaatgagtt
   135421 gaaaaaaaga ggaattatag cggatatagt accaaaaaaa tttgtagcag agtcactgta
   135481 tgaagagtta gcgcctattt taaatgatga cgataatata cttataccta gagcagaaaa
   135541 tgctagagat tatctggttg acaaacttaa ggctatttgt gaagtaacag aagtacatat
   135601 atatagaaca gtaatagatg aggagaaaaa aggtgagata ttagatattt taaattctaa
   135661 tgacatagat tatataacat ttactagttc ctcaacagta aataatcttg ttgaaattat
   135721 aggaaaagaa aatattaaaa tattagaaaa aataaaaaca ctatctatag gtcctataac
   135781 tacagagaca ataaatagtt tgggaataaa attgtacaaa gaatctgcta catctactat
   135841 agattcgtta gtagatttaa ttataaaaaa ttaattttgg aggcttgaat atgttaagaa
   135901 gaccaagaag actaagagca agtaaagcaa tcagaaattt ggtaagagaa actaaggtga
   135961 atgtagaaga cttaatatat ccactgtttg tagtagaggg ggaaaatata aaagaagaaa
   136021 ttaaatcttt accagatgtc tatcatttat caatagatat gctagaagac gaaataaaag
   136081 aaataagtga gttgggaatt gaacatataa tgttatttgg tgttccagat gaaaaagatg
   136141 agtgtgcttc acaagctttt aatgataatg gaatagttca aaaggcaatt agaaaggtaa
   136201 aagaaataaa ttcagatata aatgtaataa cagatgtctg tatgtgccaa tatacaagtc
   136261 atggacattg tgggatttta actgatactg gttatgttga taatgataaa tcattggagt
   136321 atttggctaa aatatctgta agccatgcta aagcaggagc tgatatggtt gctccatctg
   136381 atatgatgga tggaagaata caagcaataa gagaagcttt agatgaaaat ggattagaaa
   136441 atgttggaat catggcttat agtgttaagt atgcttcaaa ttattatgga ccttttagag
   136501 aggcagctca ttcagcacca tcttttggag atagaaaaac atatcaaatg gacccagcaa
   136561 atagcaatga agctataata gagactgaac ttgatatatt ggaaggtgca gatatactta
   136621 tggttaaacc tgcattatca tatttagata ttataagaag agttaaagat aattttgact
   136681 tacctctagc agcttataat gtaagtggag aatactctat gcttaagttt gctgtgaagg
   136741 aaggtttatt aaatgaagat gtaattcttg aatcaattac atctataaaa agagcaggag
   136801 cagatataat aataacttat tttgctaaag acattgctaa actgttgaaa aaataaattc
   136861 tagcagtata aagaatatca aaaagtatag gaattgtaat taactattat acagtagttt
   136921 tgtttagaca tttattgaag aataatagaa actaatttgc aatttctata ctttatttat
   136981 gtaactaaat aaaatttgga ggtagaagat gctatatcct attaatttaa aattagatga
   137041 gttagatgta gttataattg gtggtggaga agttgcatat aggaaatgta aaaatttttt
   137101 agagtttaac aaaaatgtta ctatagtttc taaacaaatt ttaaataaat tttatgattt
   137161 aaaaggaaat ataaaaataa taaaagatga ttataaagaa atatatataa aagatgcttc
   137221 tgtaataatt gctgccacaa ataatagaga gttaaatatg gaaataggat tatattgtaa
   137281 agcaaaaaat aagctagtga atgtagttga taatatagaa atatcgaact ttactgttcc
   137341 atcatatata aaaagaggag atttacttat aagtgtgtct actgggggca agagtccttc
   137401 attatcatca aagataaaaa aagaaattga agagagatat actgaagatt atgaggagta
   137461 tttaaatgta ttaggagata taagaaaaaa ggttataaaa aaatacgaag ataaaagtaa
   137521 aagaaaagat gtgcttaata tgttggtaac acttgaccta gaagaactta agaagtttga
   137581 tatataaaaa ataaaataaa aaatgttaaa aaggtgttga cggat
//
LOCUS       DAMJVG010000002       107073 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.002, whole genome shotgun sequence.
ACCESSION   DAMJVG010000002 DAMJVG010000000
VERSION     DAMJVG010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 107073)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 107073)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..107073
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.002"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(56..1327)
                     /gene="serS"
                     /locus_tag="PC512_000138"
     CDS             complement(56..1327)
                     /gene="serS"
                     /locus_tag="PC512_000138"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HDF2439918.1"
                     /translation="MLDIKRIRENLDCIKKAMERRGEKNFNLDEVVKLDDERRKTLQE
                     VEVMKNELNTASKNIPNLIKEGKDVENEKIKLKELSDKIKVIDQNLKEVEDKMEYLLM
                     RIPNVPHPEVPQGETDEDNVEVRTWGKTTTFDFESKAHWEIGTELGILDFETASKITG
                     SRFTLYKGLGARLERALLNFYLDTNTKVNGYTEVIPPFMANRNSFLGTGQLPKFEEDM
                     FKIEGMDYFMIPTSEVPLTNIHANEILKFEQLPINYTAYTPCFRSEAGSAGRDTRGLV
                     RQHQFNKVEMVKIVAPEESYNELEKLTNNAETMLQLLNLPYRVVKICTGDLGFTASFK
                     YDVEVWMPSYNRYVEISSCSNCEDFQARRAGIRFKRDKDSKAEYVHTLNGSGLAIGRS
                     VAAILENYQQEDGSVVVPEVLRPYMGVSVIK"
     gene            complement(2143..3747)
                     /locus_tag="PC512_000139"
     CDS             complement(2143..3747)
                     /locus_tag="PC512_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2439919.1"
                     /translation="MKAKIYYNGNIITMEDSICGDAILIKDKIIKKIGTKEEVFALKN
                     KDTEIIDLQGKTLMPSFIDSHSHLIAFATTLKLVPLEDATSFKDIVKKIQDFKESNNI
                     KKGDWIIGFSYDNNFLEENKHPDKSVLDSASSENPILISHASGHMGVANTLGLKQLGV
                     TNETRDPEGGHIGRVEGSEEPNGYLEENAFFNVASKIKQPSSNEIFNSIEKAQNIYLS
                     YGITTAQEGLMEENQFNILKAMANQNKLKMDVVGYVNLKKSKSVADNNREFIKKYINR
                     FKIGGYKIFLDGSPQGKTAWLSRPYENSDDGYCGYPIYKDEEVEKFIDISLKEKMQLL
                     THCNGDAAADQLIDAFEKVLNLKEQSSENNIRPVMIHAQTVRADQIDDMKVINMIPSY
                     FVAHTYYWGDIHIKNLGEDRAFKISPLKTTIEKGLIYTLHQDTPVIAPNMLETVWCAV
                     NRITKKGIQIGENEKISPLDALKGVTINAAYQYFEEDKKGSIKEGKLANLIILDENPL
                     TIDPMKIKDIKVLQTIREGEVLYSLK"
     gene            4133..5059
                     /locus_tag="PC512_000140"
     CDS             4133..5059
                     /locus_tag="PC512_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HDF2439920.1"
                     /translation="MSKENKNVRIAVVQASPVIMDLEKTVEKALGLIKEAGRKGANIV
                     VFPEAFIPAYPRGLSFGFVVGSRTMEGREDWKRYYDNSVPVPSATTDLLGKAAQEAGV
                     YLSMGITERDGNDINCTLYCTNLFFSPEGKLIGKHRKLKPTGTERCIWGEGDGSTLTV
                     VDTPYGKMGSLICWENYMPLARTALYAKGVKLYIAPTADSREEWQATMKHIALEGRCF
                     VIGCNQYVEKNTYPTDLNYYKELDAEPEIMCPGGSCIVDPFGKYVAGPIFNKEEMLIA
                     DLDLEKIVLSRLDFDSEGHYSRPDVFELIVHE"
     gene            complement(5179..6177)
                     /locus_tag="PC512_000141"
     CDS             complement(5179..6177)
                     /locus_tag="PC512_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhdH/YhfP family quinone oxidoreductase"
                     /protein_id="HDF2439921.1"
                     /translation="MNKKFKSLYITEEEGNFRRNIVEREVDTLPEGEVLIKVKYSSLN
                     YKDALSANGNKGVTRKYPHTPGIDASGIVESSSCDDFKIGEEVLVTGYDLGMNTSGGF
                     SEYIRVPSSWVVKLPKNLSLKEAMDYGTAGFTAALSVYKFIDSVDKNMGDVLVTGGTG
                     GVAVIATKILIKLGYSVVVSTGKLEEQKEVLLNLGVKDVIHRSEVDDNSGRPLLRPRW
                     AGVIDTVGGNTLATAIKTTNYCGAVTTCGNAGGVDFTSSVYPFILKGITLYGIDSVDC
                     PMNLRLKIWDLLSNEWKLDDLDDMVNVVSLEELNDSIDSIMAGKHVGRTVVDLEKI"
     gene            6281..6718
                     /locus_tag="PC512_000142"
     CDS             6281..6718
                     /locus_tag="PC512_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2439922.1"
                     /translation="MEDKYIVHFISKTKASMIKFIENKLSKNGLGELIPTHGNILTAL
                     YENNGILTMKEIAAKIGKDKSTVTVLVNKLINLGYLERQKCTNDKRITYIKLTKKALL
                     IEDTFNSISTQVKETAYHNITENEKQEFLRILKKINDNFKNAD"
     gene            6804..7391
                     /locus_tag="PC512_000143"
     CDS             6804..7391
                     /locus_tag="PC512_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin family protein"
                     /protein_id="HDF2439923.1"
                     /translation="MNLKDSKTKENLLRAFAGESQARNRYNISASVAKKEGLYIIESL
                     FNYTADQEKSHAKQFFSKLKEFAGENISISGAYPVDLYDKTAQHLKAAQHNELQEWDD
                     VYKNFGKTAREEGFESIAKLFENIAEIEKVHGDRFGRYATDLEEGTLFRRNEDIQWIC
                     THCGHIHIGKEAPKACPVCLHPQGYFLDFKNSLFE"
     gene            complement(7691..8311)
                     /locus_tag="PC512_000144"
     CDS             complement(7691..8311)
                     /locus_tag="PC512_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhbD family protein"
                     /protein_id="HDF2439924.1"
                     /translation="MEELISKKDLLSKTNISYGQLYRWKRKNIIPEEWFIKKSAFTGQ
                     ETFFPRDKILERIELILSMKEETSLDDIANMFMKKDINKEFDIDFILSKEVICNYTKE
                     IFQNLYKKEQSIGKKELLILSIIEKFLVKSIITFEELKLIVNIIEENFTSIYNESGKI
                     YLFRKFGVPFVVGCLDYKKVKFEKDVVKIIEIDLTKEINDISIKLS"
     gene            complement(8319..9086)
                     /locus_tag="PC512_000145"
     CDS             complement(8319..9086)
                     /locus_tag="PC512_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polymer-forming cytoskeletal protein"
                     /protein_id="HDF2439925.1"
                     /translation="MEKGSIKILGEGFISSGEYENIKIVGSSKSKGNVKSNEVKVLGD
                     AKFEGDINIKNFVVNGKTIIRGNLKAERVRVNGQLNIEGDAEIDDLVITAQQKVDGKL
                     KCNNVTIRGQLSVNENMYAQDIKIYGEMRNKSNIECEDIKVYGAIKCDGLLNGENIYV
                     YSGGGSYCKEIGATNIKIGRSKDAFSLIKIINIFSGKFKCNLIEGDTIELEDASIKDI
                     RGKSISLVDNCDVGNIEYSDNLSVSDNSTVKNSIKVG"
     gene            complement(9127..9948)
                     /locus_tag="PC512_000146"
     CDS             complement(9127..9948)
                     /locus_tag="PC512_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2439926.1"
                     /translation="MNEELSSLRFDGVGKCKGGIFDNVNISGTGKIEGSVKCSKFDSS
                     GSAKVFGTTECNEFFTSGLSKVEGNILASKVEISGLLRCTGNINSVEIDTSGIINVEG
                     SIKSDIIHGEGYLKANENIDCENINLSGILECNGFLNCEEVNISLNGTSNFNEVGASS
                     INIKKGHGDYCKKFRMLEKKHINFEKVSSNLISLGLLSIRKYTESKLFANIIEADEIS
                     LENSEVKVVRGKNIKIGKGCYVESLEYSESIEIDEDSIVGEIKNISEKIKLKKDK"
     gene            complement(10307..12217)
                     /gene="phnW"
                     /locus_tag="PC512_000147"
     CDS             complement(10307..12217)
                     /gene="phnW"
                     /locus_tag="PC512_000147"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HDF2439927.1"
                     /translation="MKKIYGEKIKAVVFDWAGTTVDYGCFAPLNVFIEIFKRRGIDVT
                     MEEARKPMGKLKIDHIREMCEMDRIKNIWSDKFGKVPTEDDVNELYAEFEPMLFETLE
                     EYTTPIPHVVETIEKLRKNGLKIGSTTGYTREMMNIVEPNAAKKGYSPDFLVTPSEVS
                     QGRPYPWMCYKNAEALGVSPMSSMVKVGDTISDVKEGVNAGMWSVAVIKGSSELGLTQ
                     EEVENMDKEELKAKMSIVSKKFKEAGAHFVIETMAELEDILIKIENETIKSDFVPEND
                     YILLTPGPLSTTKSVRASMLKDWCTWDVEYNNLVQDVRRRLVSLATQNTDKYTSVLMQ
                     GSGTFSVEAIIGSTISKDGKLLVIANGAYGKRMKDICNYLNIQFVDCTFKDIEAVDLN
                     VVENLLKENKDITHISMVHCETTTGRLNPIQEVGKLAKEYNKIYIVDAMSSFGGIEID
                     VEDFNIDFLVSSSNKCIQGVPGFGFIIANKEKLSKCKGIAKSLSLDVYAQWETMEKNN
                     GKWRFTSPTHVVRAFYQALLELEEEGSVEKRYARYKENQFTIASRLKSLGFDTLVNDN
                     AQSPVITTFLYPKNAKFEFMEFYTYLKDNGFVIYPGKLTDIDTFRIGSIGEVYPTDME
                     RLADVIEKFINR"
     gene            complement(12496..13281)
                     /locus_tag="PC512_000148"
     CDS             complement(12496..13281)
                     /locus_tag="PC512_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDF2439928.1"
                     /translation="MSLNSIDRKKEILKLLDSKGKVNTKELVKRLEVSSETIRRYLEE
                     LENENKLKKVYGGAIKINYGVIEPEHIKRNNTNLDKKQSIAKYAAKFVNDNESIIIDE
                     GTTNLQIVDYIISVNNLKIITNSYPVLSKLISYENQGLFDGEVIFIGGKVNLKHQRTA
                     CPISIDAMKNLYVDKAFISSEGILDSFGISSIDQNKALLSKAYIKNSKESFVLCDSSK
                     IGIASMYKIADLEELDFVICDVEPPNEWKDKLNEINITWIEAK"
     gene            complement(13498..13728)
                     /gene="dltC"
                     /locus_tag="PC512_000149"
     CDS             complement(13498..13728)
                     /gene="dltC"
                     /locus_tag="PC512_000149"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HDF2439929.1"
                     /translation="MQETVIEIFEDVLGTDEIREDLDLNLFETELLDSLAIIEVLLEI
                     ENRLGIELQPTDLERKDMSTVNNLVKFLETRK"
     gene            complement(13747..14895)
                     /gene="dltB"
                     /locus_tag="PC512_000150"
     CDS             complement(13747..14895)
                     /gene="dltB"
                     /locus_tag="PC512_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HDF2439930.1"
                     /translation="MIFSQYGDYFYLYILLLTSIPAVILGLMGKNIKYYGMLASLFMI
                     FLIVGIDVQLKYLVIFIILEVIIVKGYEYVRRKTKNKYIYWGFLFASMLPIIINKISP
                     VTSFGIIGFIGISYLNFRTIQMVIEIYDGAIKEVKISKMLYFMLFFPTLSSGPIDRSR
                     RFEQDLEKQISRKEYIEEYLLPGIKNIVMGVGYKFVIAFLINTYWVSRIPKDMSFINI
                     LSYMYAYSLYLFFDFAGYSLFAIGTGYIFGIQVPINFDKPFISKDMKEFWTRWHISLS
                     RWFGDYIFSRFVMSSMRKKRFKKRTTAAHVAQMITMITMGFWHGLTWYYVAYGVYQGL
                     ALVLTDIYQRKSKFYKKHKKDKWFERVQIFITFHIVCFGLLIFSGYLA"
     gene            complement(14895..16409)
                     /locus_tag="PC512_000151"
     CDS             complement(14895..16409)
                     /locus_tag="PC512_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase"
                     /protein_id="HDF2439931.1"
                     /translation="MKIIEGIKKYSNTDRTALMCNGDKLSYKDLNEYSDAISVFLKDV
                     YKEEDTPIVIYGNKENMIMACMIGALKSGRAYVPLDISFPIDRVFEVTKEIKPKVLFN
                     FSDERNFGDINVIDMDKLNYIINEYQGKSLDKENWVKDDENAYILFTSGSTGKPKGVQ
                     ISSNNLDSFSDWISPYLNIDGSEKVIMNQPAYSFDLSVTTIYPGLIHGATLFSISKDV
                     LADYKELFRQFSISDIAVWVSTPSFAGVCITEKEFNSKMLPNLESMIFIGEALSKNLT
                     KELMSRFPNTRIINGYGPTEATVGVSVNDMTQKAIDDEKSLPVGYPMSNCKIKILDED
                     GNELKENEKGEIIIIGPSVSKGYFNNKEKTDEVFFYDEIDGVKWRAYKTGDMGYLLDG
                     NIYYCGRKDFQIKLNGFRIEIEDIENNLRKVHNVKNAVVLPVYKDEKIAYLKGIVELN
                     EKNDLSNIKNGMIIKKELGKYIPSYMIPRNISIISEFPTNINGKIDRKKLMEEI"
     gene            complement(16530..17720)
                     /gene="dltD"
                     /locus_tag="PC512_000152"
     CDS             complement(16530..17720)
                     /gene="dltD"
                     /locus_tag="PC512_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HDF2439932.1"
                     /translation="MRKLIYFITPFIIGVVFLFGLDKFLDSKTDELLREKNLLPIMDD
                     TLSDIKDKGVTANNHFLREKDIMILGSSELSNSTKQHPKYYFNTNRSKNKVFAIGRAY
                     TQTLQDAAILGSMNPNIDNKKVVLLISMQWFMEKDGVTSHHYQSRFSPIQFYRFLDNP
                     KISKQNKIEYAKKSSKLLWGSDEYKAEALYAKLYEPKTFPEKAEKVLLEPYFQGRKYC
                     IALKEKGILYKRLIKLDKKRATKRKRPINWSYERKKAIEDAKKRVGKNPLNIDKYYYK
                     EHFKDGIEQYKGRDKDVNLLTSKEFENYKLMLNVCTDLGIKPVVVLIPSMDKFYNLTG
                     ISEKERNQYYDKAQKIAESKGFEVLNLKDKGSDKYYLRDVMHLGTKGWVDVCERLFKI
                     FKEQ"
     gene            complement(18008..19027)
                     /locus_tag="PC512_000153"
     CDS             complement(18008..19027)
                     /locus_tag="PC512_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDF2439933.1"
                     /translation="MMGKIRFGIVGTSNIANIFLRAASRVKDFELVAVYSRNLEKARE
                     FGTLYGASIFFDDLEQMAKSKDIDAVYIASPNALHSKQTITCLKHKKHVLCEKSLASN
                     LKEVKSMIKTAKDNNVLLMEAMRITCVPNFKAVKENLYKIGKIRRFFGSYCQYSSRYD
                     KYKNGIIENAFKKELSNGALMDIGVYCIHPMVNLFGAPKTVKAVSHILQTGVDGEGSA
                     VFQYDDMDAIIQYSKVADSYIPSEIQGEEGSIIIEKLNLFEKAIIKYRDGREEDISIP
                     KEKAEEKPREIEGMYYELVEFISLINNNKIESNINSHENSIIVMEIMDEIRRQSSIVY
                     PADSI"
     gene            complement(19203..19742)
                     /locus_tag="PC512_000154"
     CDS             complement(19203..19742)
                     /locus_tag="PC512_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative ABC transporter permease"
                     /protein_id="HDF2439934.1"
                     /translation="MDNVGSLLYFLFNFFLYGFIGWIIENLYSYYKQGHFQEDGFLNG
                     PFKPMYAIAMSIIIEVSRFIDPNNIFALLLLCLVVPTVVEYITGILMKVYFNKVYWDY
                     SDYKYNSRGIVCLKFSVYWTILTFIGVRYFQVYIVDSLYSLIIPYWPIVVTILLVTLF
                     VDEILTIKFLRGNKDIVER"
     gene            complement(19843..20523)
                     /locus_tag="PC512_000155"
     CDS             complement(19843..20523)
                     /locus_tag="PC512_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HDF2439935.1"
                     /translation="MQKVEGIIFDMDGVLFDSERISLEFWMETFEKYGYTMTKEIYTS
                     VMGRNRKGIIEGLTDIYDSSVPIIDLYDEKTKNMIEFMERKGAPIKLGVNELISFLKE
                     NGYKMAVATSTKRERAVKRLAKANLKDYFDAIVCGDDVVNSKPNPEIFLKAAKKINVN
                     PKNCIVIEDSPMGVEAAYNGGIRCINVPDLKEPDEQIKSQSHKILENLLEVREYLKSL
                     NSKECHNL"
     gene            complement(20552..21841)
                     /locus_tag="PC512_000156"
     CDS             complement(20552..21841)
                     /locus_tag="PC512_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HDF2439936.1"
                     /translation="MRELLKVTLIVMLVLINAFFVACEFAMVKLRSSRIDTMITEGNN
                     NAKRCKIIKDNLNSYLSACQLGITLCSLALGWMGESTVKELILPIVSVFNLSESIIYT
                     ISISISFLIITMMEVVIGELVPKALALYNTEKIMLSTSFLLVGFYKLTYPIIYFFNLS
                     TDLFLKPFGYSQADEVDEPHTGDEIRLLVEESYKSGLIDESEQRLVDNIFEFEEKKIR
                     EIMVPRTDMVCIYESDSEEKILAILKEEGVTRYPVCRKNKDDILGFVHIRDLYNQKIN
                     ENKIELEEILRDIIYISENLTIDKALERIRKEKLQLAIVVDEYGGTSGVVTIEDILEE
                     IVGEIQDEFDKEETHIKKIGAGSYLVDGTESINYINKYFGLDIEHDGFDSIGGWISYM
                     LGSNIKVNQSVTFENYNFTILELDKLRVVKLIIKSVI"
     gene            complement(22290..23891)
                     /locus_tag="PC512_000157"
     CDS             complement(22290..23891)
                     /locus_tag="PC512_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HDF2439937.1"
                     /translation="MIYDLILKNGFIIGGTGNPGFYGDIAIKDNLIAKIDSKINSNTN
                     KEIDCCGKVITPGFIDPHVHEEIVAILDGKFEKFLKQGVTTTINGNCGHSITPYSSEN
                     VYEYMYKNGLLLEEEKKYLIDKNKCWNNFTEYCDLISKSGISVNMGFLLGHGTIRWSV
                     MGGSKDRPPTEKEKNEITDIINDGMKSGAFGISTGLAYIPSKYADIDELVDIAKQIKE
                     HDGIYTSHIRDYIGRYNAVKEAIEVGQKSGARVQVSHLSPVEIEAFDEILKARYNGVE
                     IMVDTVPRSSGHCMKKKRVIQFIMAISSSLFELGINGVMDALRNEEGRTLILKEAFIL
                     GDRGSIILLNTKDINMEKKSIREIATQKGIDEDKLLLDLLLDGDEELIFCLGGMYRAD
                     FPDKLHDDKIIDNPFVMVGSDCLFSVGGDMSWFELQRRGAFPIFFNMYRKSGVRLEEI
                     VRRVTSLPARQFKIKNRGILKEGLIADIAVIDMDNYSYSRSEDIDFSKPQLLANGVEY
                     VIVNGKIALENGEITENKCGEVLKR"
     gene            complement(24002..24679)
                     /locus_tag="PC512_000158"
     CDS             complement(24002..24679)
                     /locus_tag="PC512_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2439938.1"
                     /translation="MSKVKSIYNEEYLPFKIRYGRLTLSLGIIAALVPGIILSFGFGI
                     MPPISALLASTMAIVSMSAPNYIIEPVSYSPILGIPGTYMSFLSGNISNMRLPCSIAA
                     QKAAEVESGTEEGSIISTIGIAVSILVNISILTIGVILGGSVLSKIPAEVVEKLNLIL
                     PALFGSVFGQVFLQDKKLGLVAIVISVLTIILSKQGIIPQSLVVLICVFGTMLIARAM
                     YKDKLSD"
     gene            complement(24692..25387)
                     /locus_tag="PC512_000159"
     CDS             complement(24692..25387)
                     /locus_tag="PC512_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5058 family protein"
                     /protein_id="HDF2439939.1"
                     /translation="MDYLKLANHPLLWIASTVAVSIVVVQSLIFAIKSCKVGKTMGIT
                     DKQIKSAVKSSAISAIGPSMTIFAGMVSLIVTMGGPIAWMRLSFIGSVIFESMSAGFG
                     TDALGITLGSPEMTKLAFTNAVWTMILGSLGWIIFTLLFGHKLDKITNVISSGKKSFI
                     PIISLGAMLGSFAYLNADRVLRFDNGTIACISGMAIMVILCMLEKKKNIKWLREWGLT
                     ISMFSGMIIASVI"
     gene            complement(25439..26638)
                     /locus_tag="PC512_000160"
     CDS             complement(25439..26638)
                     /locus_tag="PC512_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HDF2439940.1"
                     /translation="MKSAYKGYEAYSYLEKGKDISSIEMCKGDKRVKEYLIELDDIQE
                     AKVKSIVDEKIFISLHEHPVLFPEHLERDIFEYNREGKQRCAYEALSRGYYDAIFDNL
                     MDGVCTITSNSGWKWDDILIDLGMRLCDLAHQDFVIKCEKVEDIYRAKSEGKVALIPT
                     LEGAAPIENELDRIDILYGFGIRLMGITYSESNALGSGLKEEKDGGLTNFGKKAVERM
                     NKIGMAIDCSHVGVQTTLDVIEYSKDPIILSHVGARSLWNTKRLTPDEVLIACAKKGG
                     VIGVEAAPHTTITEKNKEHSIESFMEHFEYIKNLVGIDHVAFGPDTVYGDHVKLHSVL
                     AAKFDIKKITGTKEHPKVEYVKGLENPTETSKNIVRYLVKHGYSDEEIEKVLGGNILR
                     VLKQVWK"
     gene            complement(26899..28944)
                     /locus_tag="PC512_000161"
     CDS             complement(26899..28944)
                     /locus_tag="PC512_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2439941.1"
                     /translation="MKKHNILFVSTDDKINIDISKQLENIFGEFCNIDNLVYVNRINI
                     ELSSYELVVCSDNDIKEYIHNNIDKNIPIVIVHRTINIENINQIISIENDSDVMVIDA
                     YKESADETAKIIRKLGLIHINLIPYYPGCDKSKCEIGIITGSRNSIPQNIKQIIDIGD
                     KVIDINTVIEIFTKLNISIDKLHIIKEKYNEDTVSGYRYYTTMNKTMKSFLEIIDEGI
                     ASVDKLGKFIYCNKVFSNLVGIDQNEIISNNFMDLFSDKVVKKIFFQEDEVNDEVVNL
                     NNKKLIINKVNVYENNERIKSIISIKNISAIQVLEDKIQNKLQSKGFVSKYTFESVVG
                     ESKIIKEKINIARKIATTDFSVLILGENGTGKEIFAQAIHNESLRKNKPFVAVNLSSL
                     SDTLIESELFGYDEGSFTGAIKGGKMGIFERAHTGTIFLDEIGDISLDVQQRLLRVLQ
                     EKEVMRMGGSKIIPIDVRIIAATNKDLKKKIKEGSFREDLYYRINVLHIEIPRLRERK
                     EDIPLISKYFLDEINSNKCFTEESMQALTLYEWPGNVRELKNLIYYIDTIVEEDRVDY
                     EHLPEQFRFEKNNTLVNENFDSIILDFKQSNFFEESICILTSIETWNNKNILLGRNKL
                     QEILKEKDIVLSVDQIRKRIDKLKSHGLLLSGVKKQGSFITDEGKNFISYVKIKGVI"
     gene            complement(29355..30164)
                     /locus_tag="PC512_000162"
     CDS             complement(29355..30164)
                     /locus_tag="PC512_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2439942.1"
                     /translation="MYYVYVNDINIAVYDLNPSAKKTVLFIHGWPLGHKIFEYQTNIL
                     PKLGYRTVSIDLRGFGKSDATSGGYTYSQLADDIYKVVHAIGLKDFTLVGFSMGGAIV
                     LRYMSLFNGYGVSKLVLAAAAAPSFVQRPPEFPYGMTREDVNKLIAQACTDRPEMVTD
                     FGEKVFASNPPESFRRWFNDIGFSASGIGTIGTAVSLRDEELFNDLKCVRVPTGIFHG
                     KLDEICPYEFAVFMNEKIEDSILYTFEYSGHAIFYDELKLFNQKFLQFLEE"
     gene            complement(30248..30781)
                     /locus_tag="PC512_000163"
     CDS             complement(30248..30781)
                     /locus_tag="PC512_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HDF2439943.1"
                     /translation="MSDAHYDMHKRNGYSSDEPYPEIKVLGPNKYYAELLMDDYAGVS
                     SEFTSVNQYLYHNFDLDETHRELSEMWINISITEMLHMEILAKTIRLLGGNPVYRGST
                     SSCGAYWNGGFVCYGNSICNRLKLDLHLEHVAINNYYKDISLIEDPYIKAILNRIILD
                     EKLHVSLFEKAIEKYCK"
     gene            complement(30931..32280)
                     /locus_tag="PC512_000164"
     CDS             complement(30931..32280)
                     /locus_tag="PC512_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TldD/PmbA family protein"
                     /protein_id="HDF2439944.1"
                     /translation="MELKNFKDILFKKALSEGFEEYEIYYYTGENLSINIYEGEVEKY
                     NLDKSFGLSFRGKVNGKIGYSYTEILDDKAVDMLIKNVKDGVNTIENEDVQFIYEGDK
                     HYNDVKTYSKELENLEADKLIDLALEMERETKAYSDKVVNLSKCTISYSVSSNGISNT
                     KGLNLSNKTNMLIGFVVPIIEDNGQKYDGIGYNIANSIEEIKPCEIAKLGVDNALSKV
                     GGKSIPSGKYKTILLNEAMVSLLSTFSGIFNADSAQKGLSLLKNREGDMIASPIVTIV
                     DDPLLENGMASTPFDDEGVATFKKEVVLNGKLITLLHNLKTANKAGVKTTGNGIKSSY
                     SSPISIYPTNFYIEKGDKSLDEIIKDIDEGLMVTSFAGLHSGANSVTGDFSLAAKGFY
                     IKEGKKVFPVEQITVAGNYFDLLKDIEAIGEDLEFPMSSIGSPSVVIKELSVAGKDE"
     gene            complement(32292..33674)
                     /locus_tag="PC512_000165"
     CDS             complement(32292..33674)
                     /locus_tag="PC512_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TldD/PmbA family protein"
                     /protein_id="HDF2439945.1"
                     /translation="MLSKNIASKVLEKCLITGGDFAEIFEEDTINNSISLIDNKVENA
                     IGGRNYGIGIRIFKGLKSIYAYTSDNSLNSLLDVAYKAAVALGKLEDGKSVILNDSIK
                     INNIHNIKIYPNSIGNKDKVSVMKVAYKSAKEFSNDISQVSVSYLDKDQKILIANTEG
                     IYVEDRRIRTRLGISSIASKGNENQTGFEGPGGCKGFEIFEEIDPEYYAKESARVAHT
                     MLHAKNCPAGNMMVAIDNGFGGVIFHEACGHSLEATSVAKGNSVFADKLGQQIASTKI
                     TAIDDGTIPNYWGSMNIDDEGNPTQKNILIENGILKSYMIDKLNGRRMGMNPTGSSRR
                     QNYKFAPTSRMTNTYIAAGEDRPEDIIKSIPDGLYAKKMGGGSVNPVTGEFNFAVSEG
                     YLIKNGEIQEPVRGASLIGKGSDILMNIDMVGNNVKQAQGMCGSSSGSIPTNVGQPMI
                     RVKEITVGGR"
     gene            33918..35132
                     /locus_tag="PC512_000166"
     CDS             33918..35132
                     /locus_tag="PC512_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HDF2439946.1"
                     /translation="MNQEYVKGNPIFTNINKVPRQFPYLTDDIDTDVIIVGGGVTGCI
                     CAYYLAKNNIKSVILEKGRIAHGSTSVTTSLLQYELDDNLIDLTEVMTLKDALKAYNL
                     CTSALEELDTFIELYGNKCDYAKRDTLLYTANKLEVKAIKEEYNLRKENGFDVEYIDE
                     STNPFNFDLKSGLIAKNGGRELDPYKYSHHLIDVSLKNGLQVYENTEVKKVDLSNDKV
                     TAEVSYGYKVHGKKLIVATGYNTSLFTKRNFATKSNTFNIATKPLKNIASWKNNILIR
                     DNCDPYNYLRTTKDNRLIIGGEDVSFDDIENETLANEKYDILEQRLKSMFKDIKDIEV
                     EYKYCGCFASTLDNLGFIGPDNKNNNLWYCLGYGANGILFAILGGIMLSELYLGKQNK
                     NMKLFKVDRFDK"
     gene            35309..37222
                     /locus_tag="PC512_000167"
     CDS             35309..37222
                     /locus_tag="PC512_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2439947.1"
                     /translation="MKYGGIIMKEILVIAPTKGTYEKSIHIVKKNKYTNIDVVFGNLK
                     EGIPLAEKSINHGTRIIISRGGTYNMLKATYNIPIVEIKVDAYDIIKSYKEVKNSNEP
                     FGIIGFNNVIYGFDIIEEILNKKITMIEIEKEEEIYDAIEKYRKKGINTYIGDTTVAH
                     IVKRLNCKGILIESREENILRAIQQAEQILEATKDEQKRRLQIEAMTDFVHDGIITVD
                     KNFKITLFNKSAEKIFGIKKENALYHNVVDVIPNTVLPQVVETMEPQIGEIQNIGSTK
                     IITNRVPIIVDGQIQGAVSTFQDSKEISSFEHTIRRSLLSKGLSAKYTFDDIIHASEK
                     TKDCIELAKKYACYDTPMIITGESGVGKELFCQSIHNYSKRKNAPFVAVNCAAIPPSL
                     IESEFFGYEEGSFTGARKKGKAGVFELAHEGTIFLDEISEIPLELQGRLLRVLQEKQV
                     MRIGGDKVIPIDVKIICASNKDLKNMMRNGLFRQDLYFRINILTLYLPSLKERKEDII
                     KLSEFFIHKYSSKYNKTPLIITPNIKKALLEREYEGNIRELEGMMERAVIVESFDSIL
                     LEKVSNEYTNNIVDKDNSDFECSNLDLKTLEKKYIYKIYNENNRNTTKTCEILKITRS
                     TLWRKLKEIEDDV"
     gene            37493..38467
                     /locus_tag="PC512_000168"
     CDS             37493..38467
                     /locus_tag="PC512_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate permease"
                     /protein_id="HDF2439948.1"
                     /translation="MHILKSVKKIPGGLMVCPLLLGALFNTVCPQALEIGGFTTSLFK
                     TGAMSILALFCLCNGAQINIRQAGKPLTKGIVLTATKFIIGAVLGIIVSKFIGPKGII
                     GITPLAIVATMTNSNGGLFAALAGEYGDSTDVGAISILSLNDGPFFTMLAFGVTGLAN
                     VPIIALFAALIPILLGFILGNLDEDIREFLAPGTTLLIPFFAFPLGAALNFNQIITAG
                     LPGVVLGLGVTIITGMGGYFVMKLIRAEHPAVGAATGTTAGNAAGTPEALAAIDPTLA
                     TIAAVSTVQVAAAIIVTAICCPMLVSYLDKREKKKKSIFKTNKNIEVN"
     gene            38488..38763
                     /locus_tag="PC512_000169"
     CDS             38488..38763
                     /locus_tag="PC512_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HDF2439949.1"
                     /translation="MNAIIHANEKDNLVTCVRPLVKGEKVSIDGKSYIVNDNIPVFHK
                     MATEDVKKGDVVYKYGEIIGIATVDIKTGDYVHVHNIESTRGRGDKK"
     gene            38776..39939
                     /locus_tag="PC512_000170"
     CDS             38776..39939
                     /locus_tag="PC512_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HDF2439950.1"
                     /translation="MKLMGYLRENGQFGIRNHVLIIPTSVCSSETATRIASLVPGAIA
                     IPHQHGCCQIGSDIELTAKTLIGFGKNPNVAAVLVVGLGCDGIQAKELASEIATTGKK
                     VDYVVIQECGGTLKTVSKGAEIVSKMAREVSKEVRVEFGMSEITLALECGGSDPTSGI
                     ASNPSIGVASNLLVDEGGSSILSETTEVIGAEHLLATRFEDEEMKDKFLKFVSDVEKR
                     AIAMGEDLRSGQPTPGNKTGGLSTIEEKSLGCMYKAGNKPFKGALEYADIVPPDKKGL
                     YFMDTPGQDIDSITGMVAGGAQIVIFSTGRGTPTGSPISPVIKITGNSDTYNKMPDNI
                     DINAGRIITDGAKIADIGQEIFNEIIEVCNGKHTKAESLGHREFGIYRISSTF"
     gene            40276..42555
                     /locus_tag="PC512_000171"
     CDS             40276..42555
                     /locus_tag="PC512_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF2439951.1"
                     /translation="MNFENTKNKKIIATLLLTLLLIVSLTCVTFIMNLNKVTHNETER
                     YLVEVSQGISTTINVKCKSIFRTLYSMGDTYFEINDSEKEVNRYLSKKLKLFEFDWLG
                     IIDSNGNFVSALKDTGNVKGQDFYRKALQGKETITPVKSQSGTYGILYSVPLYNGDKI
                     VGAVAAWNTIDTMRNLLSVESFHGEGFSQIIDQDGNFIVSSANKNAPKNVVNFFDMIK
                     HQGKQVDKNKLEEMKINLKKNKTGSMYYTLNDGISKAMHYLPLQEENLYLLSIVPTKT
                     ASAQFDLLLKKAIFINILIVILFLLLIILIMFINQKNRAQLIKIAYVDSVTKGYSKAR
                     FDIEAKKIIQSSSSESYSLVSINIQKFKLINDSFGSEAGDKTLKYIHDVISNYLEPGE
                     LLCRVSNDQFNVLIKTIPQKEILKYIENITNDINSFNKNEECKYFIALSIGVYKIDDP
                     NLPLVSIQDRANVARKNNKGNIGNHPLYTCVFYSDLERLKMIKEKEMENRMEEALNNN
                     EFIVYLQPKISLKDNTIVGAEALVRWQDPNKGLIPPDEFIPFFEKNGFITKLDHYVFE
                     KVCSMIRKWIDNGETPIPVSVNFSRANLNNIDFLEKYRMLRNKYNIPAKLLEIELTET
                     LVFENLQKLINIIDQIHEEGFQCSLDDFGSGYSSLNMLKEIKVDTLKLDRAFFSSPNA
                     DNIAENHVIESIVNLAKKLNMNSISEGVETILQMDYLKKINCDMIQGYVFSKPLPQEI
                     FEKMTFGKKLEETSMDSSV"
     gene            complement(42650..43990)
                     /locus_tag="PC512_000172"
     CDS             complement(42650..43990)
                     /locus_tag="PC512_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2439952.1"
                     /translation="MENQEALRHEKIWILLFRYSIPAIIAMMVTSLYNVVDRAFIGSM
                     EGIGSIAIAGLGVTMPVFTLIIAFGMLVSVGASTRLSIKLGERNREEAEKILGNALTL
                     SIIISLIITILGLVFLEEILFILGASKDSIFYAKDYMSVILVGSIFNLVAFSLNNAIR
                     AEGNPKLAARTMIVGCVLNLILDPIFIFVFNLGIKGAAIATVLCQIVVFFWVIHYFIR
                     GKSNLKLKKCNLKLNKDIVKKVFAIGMTPFAMEVAISITHMFTNNSLKVYGGDLAIGA
                     MTALTSILLMFMMPVFGLNQGMQTIISYNYGAKQYERAKKTLILSIIVSVVILSFGFL
                     VVQVFPEVFVGIFNKDSDLMDIAVRGISLNLITLPIMGISIVGPVYFQCISKVKHSMF
                     LTLLRQFILFIPLIIVLPIQFNLDGVWLAQPVADFIAMIIVLLFLKREFKTSRV"
     gene            complement(44002..44784)
                     /locus_tag="PC512_000173"
     CDS             complement(44002..44784)
                     /locus_tag="PC512_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004460318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2439953.1"
                     /translation="MNCINTKNLNVSYGNTDIIKNLNLNIPKGKITTIIGANGCGKST
                     ILKTIGRIISPNSGKIYINGEDIYKKKSKEIAKDMAVLPQSPQAPSGLTVSELISYGR
                     FPHKSGFGNSSKEDREIVNWSLEVTGIAEFKDRNMEDLSGGQRQRAWIAMALAQETDI
                     LLLDEPTTYLDLAHQLEILKLLDELNKKQGRTIVMVIHELNNAARFADHMIGIKKGKI
                     VCEGDAYDVMTKDNLKELFNIDAEIATDPRTNKPICITYDMV"
     gene            complement(44799..45821)
                     /locus_tag="PC512_000174"
     CDS             complement(44799..45821)
                     /locus_tag="PC512_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HDF2439954.1"
                     /translation="MKNIIKINSKTLLVISILMVLIFITFLLSLNMGSFSIEPMDVIK
                     TFLGQGQRNHEIAIFKLRLPRIVIALLVGSALSTAGVILQGVTKNDLADSGILGINSG
                     AALFVVVYIYLMNGNVYEGMSNLTVFTMPIVALIGALFGAFLIYSLAWKGGINSSRLL
                     LIGIGVNIAFTSILTIFQLKFTTQEFNRVMAWTSGSIWGTSWKYVIAVLPFIVIFMGI
                     TIYKSKYIDVLNLGDEVSISLGVDVEKQRRRLIIYAVILSGVSTAVAGSISFLGLIAP
                     HIGRKIIGPKHKRLIPVSALIGTLLLLIADTISRNLLAPIEIPVGIVVSIIGVPYFIY
                     LMLVND"
     gene            complement(45827..46840)
                     /locus_tag="PC512_000175"
     CDS             complement(45827..46840)
                     /locus_tag="PC512_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HDF2439955.1"
                     /translation="MTKLSKKNITYLLILVSIVVLVFGIVLSITIGAKDMNLSTVIDS
                     LIKMEDGINMRIVKDVRLPRAIAAALVGGFLAVSGAIMQGITRNPIAEPSVIGITQGA
                     TFAISISLVLQKKLPQLIHGSFSVMMFAFIGASISGLFIYFISSKSRGRVNNVKLALA
                     GVALGTLLISLASAISMYFNLSQQLSFWISGGLVGVKWEGIKLLFVAGGIGFILAIIM
                     APRITILSLGEEVAIGLGQKTKFVRFICIVLVILMTGASVSVSGNIIFIGLIVPQIAK
                     GIVGSDYKYIIPSSLVLGAVLLVYTDILSRMINPPYETPVGSITALIGVPIFIYLVRK
                     GEK"
     gene            complement(46968..47906)
                     /locus_tag="PC512_000176"
     CDS             complement(46968..47906)
                     /locus_tag="PC512_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2439956.1"
                     /translation="MKKIKSLAIFISIITTLVLVTACSDKNTEDKDKSETRVVQSVKG
                     EVKIPSNPKKIVDISGSSEELLLAGYKPVATANVDSYETDKLPSYIREELKGVKIVGH
                     SMMDTMDMEAILEVNPDLIIMSQRQEKIYDQLKEIAPVVMMKDYANDWRSKLTDVSKL
                     FDKEEEDKSWLQKYDEKATKLGKEVIEKNGEKTYLPVLASSGQFMVFSDGGIGTLIND
                     DMKLARPKNMPKQDGITLPMVSMEGLTDIDADHIVVIATEADKKDLENSAIWAQIRAV
                     KDGNVTILDAAPFFSQSYNPIGKELLLESVKNELTK"
     gene            48176..48640
                     /locus_tag="PC512_000177"
     CDS             48176..48640
                     /locus_tag="PC512_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016208838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2439957.1"
                     /translation="MVHLVYCDNAGKKGEKVLDKILDGTKTMVIRGAAGRKIPHSRVF
                     EDELLYFMEKGTAKISAKATVKKVENYVKLTEDEISKILNENQPKLNLSEKQKVRWHK
                     KCLCLVEFENVEEITPLDFDHQGNMDDWLIVEKIEDVVVGTSIPYNYEKSKF"
     gene            complement(48752..49069)
                     /locus_tag="PC512_000178"
     CDS             complement(48752..49069)
                     /locus_tag="PC512_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDF2439958.1"
                     /translation="MDEKMIEISFGIIGFAGDAKGLAFEAIKEAKSGNIDKARECIEK
                     SKESIHKAHKFQTELIQNEANGNKTEISVILIHAQDHLMTAMNFQQLAEEFIDVYERL
                     ESK"
     gene            complement(49082..49813)
                     /gene="chbG"
                     /locus_tag="PC512_000179"
     CDS             complement(49082..49813)
                     /gene="chbG"
                     /locus_tag="PC512_000179"
                     /EC_number="3.5.1.105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitin disaccharide deacetylase"
                     /protein_id="HDF2439959.1"
                     /translation="MTKIIINADDFGYCEAVNYGIISAHNNGIVRSTSMMANMPGVEH
                     GVGLLKENKTLNCGVHMTLSCGRPLLSNLKTIVDKDGFFIRRITDEIIEKMDCDEIYR
                     ELCAQIDRVKGLGIDISHLDSHHHIHTLVSLKPVIEKIVTKYNLPIRGGFEYNLEYSK
                     VVPLIDSFYKENVSEEYFIKNIDEIMKYDVVDIMSHPAFLDDYILNSTSYAIDRTKEH
                     KILTSKKVKEFLEKNGLVISSYRDI"
     gene            complement(49839..51149)
                     /locus_tag="PC512_000180"
     CDS             complement(49839..51149)
                     /locus_tag="PC512_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HDF2439960.1"
                     /translation="MKKGLKIVTIGGGSSYTPELVEGFINRYEELPVKELWLVDIEAG
                     KEKLEIVGNLAKRMVKKAGVDMKINLTLDRREALRDADFVTTQLRVGLLDARIKDETI
                     PLSHGVMGQETNGAGGLFKALRTIPVIFDIIKDVEELCPNAWMVNFTNPTGIITEAVF
                     KYTNFRRYIGLCNVPIHLKNDVAKLFNVESDRISMDFAGLNHMVYGLNVSLDGEDVTK
                     EAIDKFVKADISMQNIKAIDFNAEFVKSLGAIPCPYHRYYYKTKEMLEDELREFKEGK
                     ARGQVVKELEEQLFELYKDEKLDVKPPQLEKRGGAYYSDAACNLISSIYNDKKDIQVV
                     NTLNKGSIRDFKDEQAVEVSSVITKNGPKPISIGYLPDSVHGLVSQIKSFEVLAAKAA
                     VYGDYESALLALCINPLIPSDDLAKTILDEMLEAHKDYLPRFNR"
     gene            complement(51246..52559)
                     /locus_tag="PC512_000181"
     CDS             complement(51246..52559)
                     /locus_tag="PC512_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2439961.1"
                     /translation="MEKFMSFMDKYIVPVAAKIGAQRHLVAVRDAFIVMIPITMVGAL
                     GTLINNLPLEAYKNLMASIFGENWTTFGGDLWWGAIGTMAVFLVIGVAYFLAKSYESD
                     GLQSGLIALSIFFIMAPQIGKIVPEGGTTVVEGWGMIQQTYLGTAALFSSILIGLLST
                     EIFVRLSKVKKLTIKMPDGVPPAVSRSFAKLIPGMLTIMIFTVIGIFIKMLSNGSFLT
                     DILNTYLGAPLSNVADSLGSTMLIAFIIHILWTVGLHGANIALPFTETILMKLGGENA
                     ALAQAGATEGYHVLAGAFFDAFVYLGGSGMVLGLIVALLIAGRRRKEMIVLGGPPAIF
                     NIGEPLIFGLPIVLNPIFMIPFVLAPVICSAVSYLAIDFGLVAPVILPKIPWVTPPIL
                     GGAMATGDWTGGALALFNLILSILIYIPFVIASEKMEANKLKINN"
     gene            complement(52581..52892)
                     /locus_tag="PC512_000182"
     CDS             complement(52581..52892)
                     /locus_tag="PC512_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2439962.1"
                     /translation="MIKIMLACSAGMSTSLLVTKMEDAAKENGIEAKIWAISEVNLKN
                     EIENCDVLLLGPQVRYVLGKATEMAKPYNIPVEVINMMDYGRCNGKAVLDRAVELNSS
                     K"
     gene            complement(53092..53796)
                     /locus_tag="PC512_000183"
     CDS             complement(53092..53796)
                     /locus_tag="PC512_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2439963.1"
                     /translation="MKEPIYKVIENHVRELINSDSLKEGDLIPSEKQLSEEFNVTRMT
                     VRSALNNLVKEGYITRQRGVGSIVIANNIYDNISSVSGFTKEMESKGYKVSNILVSLE
                     IVQADENLSSKLNISLEENVWEIKRVRLANDARVSYMITYMPVKLFPNLNKTHCENSL
                     YNFVEEVCEYKIAMSEREVQAVISNEECMDNLKLEEPEPLLYISQICKLQNSEIFEYS
                     HTYHYGYTLTLNAVVE"
     gene            complement(53887..55248)
                     /locus_tag="PC512_000184"
     CDS             complement(53887..55248)
                     /locus_tag="PC512_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2439964.1"
                     /translation="MKDRLNLTEGRITEKLLKLSLPIMGTSFIQMGYNMIDMIWVGKA
                     GSKAVAAVGTAGFFPWLAMAFIMISKVGGEIKVAQSIGANNISTTKSYMKSAIEINII
                     LAIIYTISLIVLNKQLIGFFRLGDLEVITMSRQYLIIVALGMVFYFINPVFTAIFNGL
                     GNSKTPFRINTVGLITNIILDPILIFGWGFAPKLGVAGAAIATVFAQIVVTTCFIYII
                     VKSKEEYFKLRLFKEIETKYYKVLYKLGLPIAIQSGMFTVFSMLLGVIVASWGPVAVA
                     VQKVGSQIEAISWMTAEGLSVALGSFVGQNYGAKKYSRINKGCKIAITVSSVLGIITT
                     LVLVFAGESIFSIFIDESEAIEKGAVYLKILGYSQFFMCLEIITTGAFKGLGRTYIPS
                     IIITILTGARVPLAYFISRPEMLGLNGVWWSITLSSILKGILMISLFISLLKLGKLYK
                     ISE"
     gene            55747..56901
                     /locus_tag="PC512_000185"
     CDS             55747..56901
                     /locus_tag="PC512_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF2439965.1"
                     /translation="MKINKKFNRVDMQVSILTAIIVIISSSCVYFFNYTLTYKSMIYS
                     LSERSKHIYEYVERNIDKNTFTEINSKEDQSKKSYKSSKILLESVKNTTGVMYLYTAK
                     KTKDGSLVYVVDGLNSSRSDFRNAGDLIEKEIWGDLNKALDNHILLPKKIKSTSWGYI
                     FISYFPIHNDVGKVVGVIGIEFEAKHQYNTFKFISIVTPIIALLTCLISALIAVILFK
                     RISNPTYTDFANTDYLTGLKNRNAFEIDMNNLNNSNLKNLISIISIDLDGLKKINDKF
                     GHQTGDLYIKQASKIIQYVINKKYIVYRIGGDEYIIILKNLSHKEINNIINNINLKIV
                     EENSTNELKLSMSIGYAIFDEKVDVSLFDTYRRADSQMYDNKRKINKQYQ"
     gene            complement(56983..58701)
                     /locus_tag="PC512_000186"
     CDS             complement(56983..58701)
                     /locus_tag="PC512_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     permease subunit"
                     /protein_id="HDF2439966.1"
                     /translation="MNNNAISSKSISLKSKMNLDIKKCMLTVLVMSLVIFLLAPIIYL
                     FVQAFLDKDGVFVGLQNFQEYLASESLLNSLKNTVFVSVISTVISLTLALVYAYALTR
                     TKIKFKGFFKSLAMFPMFAPTMMHAIGLVYLFGNQGLVTNLLGVHVPIYGAVGIILAQ
                     IIYVFPQSFQILYISLSSTDYRLYEASNTMGISKIREFISITIPSIKYSLISSAFVSF
                     TLCFTDFGAPKVIGGEFNVLSIDVYKQIIGQQNMPMGATVSILLLIPAIISFIVTKKI
                     EKNQNSYITSKSIPYKVKTNKLRDSILGGVVGIIAFGIIAVMLTVILSSLISVWPYDL
                     RLTLEHFSMKNSIDGIKPFINSIKMSLFTAILGTSFVFLFAYLNEKTEKAPYLKSFGY
                     FLSTLPMALPGLVLGIAYVLFFNKLEFNFMDTIYIKNLFNGLYGTLLIMVICNIVHFF
                     SVAFITATTAIKKVDKELDMVAKSMGINSASILKNVTIPLCLPAVLENFMYFFLNSMV
                     TISALVFIYTASSKVAAISIVQLDDKGSTAQAAALAVLILVTNILVKVIYEFIKNRLE
                     KRTNFN"
     gene            complement(58706..59695)
                     /locus_tag="PC512_000187"
     CDS             complement(58706..59695)
                     /locus_tag="PC512_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2439967.1"
                     /translation="MSYLKINNVFKSYDQKKVLNNISLDIEEGEFLCLLGPSGCGKTT
                     LLRIIAGLEDVNSGTIILQDKDITNLEPSKRGFGIVFQSYALFPNMTAYNNIAFPLKE
                     RKVSKEKIDNKVKEVLETVGLTNEAHKYPKALSGGQQQRIAIARALALEPKFLLLDEP
                     MSALDAKVRHKLRMDIKRLQKELNITTIMVTHDQEEAITMADKIAILNGGDIMQIGTP
                     EEIYQNPQNLFTAQFIGDTNCFDNGDSILTVRPEYVQIEKSTKENYQGIISNIEFRGN
                     LLRVEIKDKLNENFIISDVSIKEWVNLNLVEGDLVKISIDEKYYLKYPKVKGA"
     gene            complement(59791..60840)
                     /locus_tag="PC512_000188"
     CDS             complement(59791..60840)
                     /locus_tag="PC512_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF2439968.1"
                     /translation="MKEFIFTCLCIVVITFMTSCISTTPQTTQGKGNNKLTIYAALEE
                     EQIAYYMEGFREEYPNIDVEIVMDSHGVIASKLLAEKDNPQADIIWGLSAMNMIELKK
                     DGALEAYKPKNYDKVDKKFKDTEDDVSWVGMSVPETAIVVNYKELKKLGIDIPKSYED
                     LIKPEYKGLITMPNPASSGTGYLTVSGLIQMMGEKDAYNYMDKLHKNIATYTHSGSKP
                     AKLAGSGEYPIGITLGYRATQQLSSGEPIEVVFPKEGSGWDLEANALVKKDNIKKEAK
                     LFLDWAISDSAMDRYAHEVAVTSIKTDNPVPKGYSKQPFEQLIKEVDLNSAAKNRSTV
                     LKTWESKYGSKSESK"
     gene            complement(61117..61785)
                     /locus_tag="PC512_000189"
     CDS             complement(61117..61785)
                     /locus_tag="PC512_000189"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HDF2439969.1"
                     /translation="MARLNINPTRMEMTRLKKLLKTATRGHKLLKDKLDELMKQFLEI
                     VRENKRLREEAENALDTAYKNFIIARAVMSQEYLGSALMMPKQSVSVDVSTRNIMSVD
                     VPVFDFKTENNQSDIYPYGLAFTSGELDSAMEAFSDAMQPLLRLAESEKSAQLLAQEI
                     EKTRRRVNALENVMIPNYIETIKYIAMKLEENERASTTRLMKVKDMVLKKALEEKKKN
                     DLVV"
     gene            complement(61791..63164)
                     /locus_tag="PC512_000190"
     CDS             complement(61791..63164)
                     /locus_tag="PC512_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HDF2439970.1"
                     /translation="MIKEYKSIQEVAGPLMLINGVEGVKFDELGEIELSNGEIRRCKV
                     LEVNGDTALVQLFESSTGINLAESKVRFLGKSLDFGVSPDILGRVFSGMGRPIDGGPE
                     IIPDKRLDINGAPINPAARDYPAEFIQTGVSAIDGLNTLVRGQKLPIFSGSGLPHANL
                     AVQIARQAKVRGTDSKFAVVFAAVGITFEDAEFFISDFKATGAIDRSVVFVNLANDPA
                     VERVSTPRMALTAAEYLAFEQDMHVLVIITDITNYAEALREVSAAKKEVPGRRGYPGY
                     LYTDLATMYERAGKMKGHEGSITMIPILTMPEDDKTHPIPDLTGYITEGQIILSRELY
                     KKDIQPPIDVLPSLSRLKDKGIGKGKTREDHADTMNQLFAAYSRGKDAKELMAILGES
                     ALSEIDLMYAKFADEFEKEYVSQGFRTDRTIEQTLEIGWKLLSMLPKSELKRIRDEYF
                     EKYMPKE"
     gene            complement(63161..64939)
                     /locus_tag="PC512_000191"
     CDS             complement(63161..64939)
                     /locus_tag="PC512_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HDF2439971.1"
                     /translation="MKTGTIVKVSGPLVVAEGMRDANMFDVVRVSDKHLIGEIIEMHG
                     DKASIQVYEETSGLGPGEEVVSLGMPMSVELGPGLISTIYDGIQRPLEKMYDISGTNI
                     TKGVEVSSLDRTTKWEFKPKKSVGDKVVAGDIIGGVQETAVVECKIMVPYGVKGTIKE
                     IYSGEFTVEDTVCVITDEKGNDIPVTMMQKWPVRKERPYREKKTPDSLLVTGQRVIDT
                     FFPITKGGVAAIPGPFGSGKTVTQHQLAKWADADIVVYIGCGERGNEMTDVLLEFPEL
                     KDPRTGESLMQRTVLIANTSDMPVAAREASIYTGITIAEYFRDMGYSVALMADSTSRW
                     AEALREMSGRLEEMPGEEGYPAYLGSRLAQFYERAGKVNCLGMDEREGTLTAIGAVSP
                     PGGDTSEPVSQATLRIVKVFWGLDASLAYKRHFPAINWLTSYSLYQEKVDVWADKNVN
                     DNFSAQRAQAMKLLQVESELQEIVQLVGVDSLSDGDRLILEVTRSIREDFLHQNSFHE
                     VDTYTSLHKQYRMMGLILKFYKSAQDAIKQNVTINDIIKLSVLEKIGRAKYVEEGDID
                     AAYDSIEDEIDNELADLIKKRGAEEL"
     gene            complement(65056..65379)
                     /locus_tag="PC512_000192"
     CDS             complement(65056..65379)
                     /locus_tag="PC512_000192"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HDF2439972.1"
                     /translation="MLMYKVGVVGDKDSIMGFLALGIDIFPAYDSDEIKKSIHKLVED
                     EYAIIYITEQASLLAKESIAKYKDYQLPAIIVIPGIGGSMGLGMNEVRESSKRAIGAD
                     ILFKE"
     gene            complement(65366..66343)
                     /locus_tag="PC512_000193"
     CDS             complement(65366..66343)
                     /locus_tag="PC512_000193"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit C"
                     /protein_id="HDF2439973.1"
                     /translation="MAEEKTYPYAVARIRVLEKQLLNRQMFIQMAEAKSPEDSLRIIA
                     EAGYADTSNNNIHNFENILTQELSKTYEILKSLAPEEKFVDVFLYKNDYHNLKVLIKE
                     EISGVDGEKYLIDGGTIPLIKLRESLANRSFSDLPKIMSSAILEAFDVYNKTQNGQMV
                     DIVLDKATFTSMKETAKESQNKFVIDYVMKVCDLTNLKSFIRVKNMKKDFDMFMNVFV
                     SGGSLDKEKFLEAFSSDTPASCFKSTSYSDVCKNGMDSGFTVFEKLCDDYLMEYVRGA
                     KFKPLTLEPLIAYLYAKESEIKTIRIILTSKLNNIDADTIKERLRDAYV"
     gene            complement(66358..66921)
                     /locus_tag="PC512_000194"
     CDS             complement(66358..66921)
                     /locus_tag="PC512_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit E"
                     /protein_id="HDF2439974.1"
                     /translation="MGNEQKMIDRIIADAKQEAQEILDKAKSEADLKVNSANEKAEKE
                     MASYTKLAEAEAEKAASKEISGAYMEAKKQILSKKQEILEEVILEAKNKLLNLKDNEY
                     EEIILNMIEKSNCTDDSEIVLSKKDKKTLKDVLSKKGIKVSDETRDITGGFIVKKGDI
                     EYNYSFEAIIAVEHEYIEQIAAEILFN"
     gene            complement(66973..67464)
                     /locus_tag="PC512_000195"
     CDS             complement(66973..67464)
                     /locus_tag="PC512_000195"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HDF2439975.1"
                     /translation="MEFLNALGNGQFLAISGAAIAALFAGMGSAKGTSIAGQAAAGVV
                     TEDPSKFGQLLVLQLLPGTQGLYGFIIAFLILSKAGIIGGDAIPTSAQGLQLLMAGLP
                     IGLVGLVSGIAQGKAAAAGVGIVAKRPEELGKAITFAAIVETYALLGLLVSFLAYNGI
                     AIG"
     gene            complement(67467..69392)
                     /locus_tag="PC512_000196"
     CDS             complement(67467..69392)
                     /locus_tag="PC512_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HDF2439976.1"
                     /translation="MAIVNMNKISIVGLEAQKSQILKLLMNRGFVQIDDSAFLTEEEE
                     LKNYLVKDSEESEVIMLEQKMSHVNQAINIVSSLVKQKKSLLAPKREFNKIDSEKEGQ
                     VYAEALELNNLHKEIGTIRSNINLLNNNKSMLEPWVNFDIPIENMETKYTKTILGTVP
                     ISANIDALRVKLEDEIPESVIGIVNSDKLMNYVYLITLKETFDDVLEVLKEFNFSVVS
                     LPNEEGTPLQAIKKYNEMIIRQENVSKDKTEEIKRHADSIHMLENLYDFYTIERDQKK
                     IIERLVKTKTTFCLNGWLPSKRADELIKEITEKFDCCVQTEEGSKEEGFPILLENNKL
                     VTPFESVTNMYSYPSTKDIDPNTILTFFFVIFFGMMLSDAAYGLIIAVVCGFVVYKLK
                     IQKGEGNLIKLIGICGVSTTVWGLIFGGILGDLIPIKALINPLEDVMTLMGMSLLFGI
                     IHIYVGLGIKAYTLIRSGKVIDAIFDIGFWYLCITGVCLLIIPFVAGDIGVFSEVGKY
                     LAIIGAIGLVLTQGRSFKGIPVKLFKGFSSLYGITSYFADILSYTRIMALCLTTGVIA
                     QVINLLGAIAGPILAVVIGVVGHTINLLINALGAYVHTSRLQYVEFFNKFYEGGGVPF
                     VPFKYKTKYTSINKKEM"
     gene            complement(69394..69705)
                     /locus_tag="PC512_000197"
     CDS             complement(69394..69705)
                     /locus_tag="PC512_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2439977.1"
                     /translation="MAFEIIKSIVEAEQTADSIKVKAVTDAESIRADAVNKCESIFAD
                     VKKQAKLMEETLIEKAVTDSRAEVDKILANAKSECLKIEKTAEERKSKAIEAVIGKVV
                     R"
     gene            complement(70335..70610)
                     /locus_tag="PC512_000198"
     CDS             complement(70335..70610)
                     /locus_tag="PC512_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif11-like leader peptide family natural product
                     precursor"
                     /protein_id="HDF2439978.1"
                     /translation="MNEKLTKILEEAKNDDEFRKELIKTREQRDVMDSFCKVVTSRGY
                     DMTVGELFSMGEEYTSNLLKSVNGGAAYPIEDWSDWYEDFFIMLSNI"
     gene            complement(70725..72134)
                     /locus_tag="PC512_000199"
     CDS             complement(70725..72134)
                     /locus_tag="PC512_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase/peptidoglycan binding
                     protein"
                     /protein_id="HDF2439979.1"
                     /translation="MIDGKEVKQESGQKNLKFKIAIVVGVLFVAYIGMAIFFRNHFYF
                     GTTINGVKASGKTVEQVNDLLASSTNSYTLNLEERNNKKEQIKAKDIDLKFTPDDKVQ
                     KIKDSQSAIGWIGGIFKSKEYNNMITLSYNKDLLEKRFNALSCFDSKNVVEPKSAYPK
                     YDSTKNAYVIVPEVLGNKVKKDDFYKLVQNSINSGNTSISLDESKVYEAPNNTKDSEK
                     LKQAIKTLDKYVGVVVTYDFSDRKETLDGSEINKWLKVDSEKNYDITFDNDAMVEYTR
                     GLSKKYSTFGDSRPFKTATGKDITISGGIYGWLIDKKKEAEALVDVVKAGKNVTREPI
                     YIQKAVSRNKDDIGNTYVEISLSGQHMWFFKNGEMLVSTDVVTGDLARGFATPSGIYP
                     LNYKARNVSLTGQGYSSPVSYWLPFNGNIGIHDATWRNSFGGSIYKSSGSHGCVNTPF
                     SKAKKIYENIEPGTPIILY"
     gene            complement(72505..73167)
                     /locus_tag="PC512_000200"
     CDS             complement(72505..73167)
                     /locus_tag="PC512_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-binding protein"
                     /protein_id="HDF2439980.1"
                     /translation="MIDISIDDKLKERWPNAKLGCIQAKVAVNKSSEKLINEINEFCD
                     TINQSLKVEDITKLDKIKDARNAYKELGKNPSRYRTSSEALVRRIIQGKGLYTINNIV
                     EINNLISIKSLYPVGTYNVSKLHSPVCFTVGDEGEQYKGIGKELINIENLPILSDSVG
                     KFGSPTSDSERAMITEDANEILICIFSFSQESDIEEYFGYAKELLKEYADGKDIETKI
                     IK"
     gene            complement(73421..75640)
                     /locus_tag="PC512_000201"
     CDS             complement(73421..75640)
                     /locus_tag="PC512_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF2439981.1"
                     /translation="MTGRNKSFTLITILFLTSLFLTMGYIYIEDTKHLLMSEAKIHIK
                     EVAVQGSQLAQRQIEKDLDVLNIFSNYYASNPDIPNEEKMKNLLDEMENQKFYTMAIV
                     DINGNAENTKGDKFSVKDREFFKNSIKGKKYVSSPYVDEVNKSIKKIAISVPLLNNDK
                     VVGVLYCTYNINTLMKLINISFYENNSISYVVKNDGTIILHPQGDSLSKNIYKLLEQD
                     NDIQEVNRLKKELQENKTGATVLNMLEERRYLGYATMDNGNSENNYIKDWNLIFSIPE
                     TVVFSNSKQIINRAVYAVLSIVLIFVAIIFYIIYIKKSNEKEILSLAYEDKVTYIGNQ
                     NKFYRECSKYLLDKPSLNYIIVYFDINNFKMINDTFGYEFGDNLLITIAKALKEELTE
                     GEVYARLSSDYFAIFCDYKNGRNKIIRKLDNIRSNIESNLSIVFEISLCVGIYFVEEG
                     EVDIQKAVNKANMARSVAKGKNINYAIYNEDVRNKLSEESMILDDIKIALVKNQFEVY
                     YQPKFSLVTGEMIGSEALIRWNHPEHGFISPAVFIPIAEKSKLILKIGRFVFERVCND
                     LYEWKKQGKKIVPVSVNLSRVELYQPDIVKFINKTIKMYNLSSDFIEIEITETVAINE
                     LNILKNVLNELRTYGFSISMDDFGTGYSSISCLRDMPIDILKLDKSFLGGIEHDERSR
                     NIAKSIVSLAKSLDLVVIIEGVESKEQAELMKQFGCDLVQGFYFARPMPAKNFLDLL"
     gene            complement(75916..78570)
                     /gene="adhE"
                     /locus_tag="PC512_000202"
                     /gene_synonym="adhC"
     CDS             complement(75916..78570)
                     /gene="adhE"
                     /locus_tag="PC512_000202"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HDF2439982.1"
                     /translation="MAHKEQVIIENKKENEVMSVGLDTVNNVESLVKKLAKIREAQKI
                     FATYSQEQVDKIFLAASLAANKQRVPLAIMAQKETGMGIAEDKVIKNHYASEYIYNAY
                     KETKTCGVIEKDEAFGMTKIAEPIGVIAAVVPTTNPTSTAIFKALLALKTRNGIIFSP
                     HPRAKNSTIEAAKVVLEAAVLAGAPEGIIGWIDEPSLELTTTVMKEVDLTLATGGPGM
                     VKSAYSSGKPAIGVGAGNTPAIIDDSADIKTAVNSILVSKTFDNGMICASEQSVIVLE
                     NIYNEVKKEFKERGAYLLDKDETEKIRNIILVNGGLNSKIVGQTACTIAKLAGFEVPV
                     DTKVLIGEVESVEIEEAFAHEKLSPVLAMYKASDFDDAVRKAEKLVEDGGFGHTSSLY
                     IDDVNQREKLDKFTSAMKTCRILINTPSSQGGIGDLYNFKLAPSLTLGCGSWGGNSVS
                     ENVGVKHLLNIKTVAERRENMLWFRAPEKVYFKKGCLGVALKELKDVMNKKRAFIVTD
                     TFLYNNGYTKAVTDLLDEMNIKYTTFFEVEPDPTLECAKIGAKAMREFNPDVIISIGG
                     GSAMDAGKIMWTLYEHPDVDFQDLAMRFMDIRKRVYTFPKMGEKANFVAIPTSAGTGS
                     EVTPFAVITDQDTGVKYPLADYELMPNMAIVDSDMMMNMPKSLTSASGIDALTHALEA
                     YVSMLATDYTNGLALQAIKSIFEYLPRAYDNGAKDPEAREKMANASTMAGMAFANAFL
                     GVCHSMAHKLGAFHHVPHGVANALLITEVMKFNSSDAPKKMGAFSQYKYPEALKRYAE
                     IASFLGLKGNSDEEKFQSLLVAIEDLKLKVGIPKSIKEFGVEESKFMDSIDEMVIQAF
                     DDQCTGANPRYPLMNEIKDMYLNSYYGR"
     gene            79074..79274
                     /locus_tag="PC512_000203"
     CDS             79074..79274
                     /locus_tag="PC512_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2439983.1"
                     /translation="MEKLKTISVFSLIISVILTIGGIGIVTYYVDNLFIRGLSVFVLI
                     MSSSFVSTTVRLIFEESKRYKF"
     gene            complement(79481..80071)
                     /locus_tag="PC512_000204"
     CDS             complement(79481..80071)
                     /locus_tag="PC512_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipicolinate synthase subunit B"
                     /protein_id="HDF2439984.1"
                     /translation="MRLEGLTIGVGFTGSFCTYDKIFIELENLVKEGANVHTIFSDVS
                     QNIDCRFGNSEEFMKKAYELTGNKPIVTIEEAEPFGPKGIADIIIIAPCTGNTAAKLA
                     NGITDSPVLMAAKGHLRNDKPLVISISTNDALSFNFKNIGILLNSKNIYFVPFGQDNC
                     KAKPNSMIAHTELIIPTIELALENKQLQPVIKSPHQ"
     gene            complement(80074..80949)
                     /gene="dpsA"
                     /locus_tag="PC512_000205"
     CDS             complement(80074..80949)
                     /gene="dpsA"
                     /locus_tag="PC512_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipicolinate synthase subunit DpsA"
                     /protein_id="HDF2439985.1"
                     /translation="MSNQYDITVIGGDLRQVYMVKKLINKGYSVVTYGISNEIINGIV
                     GKSTSLAEALSKSSIILCPIPFTKNQVNIENTDDCLDATIDNLLINLSPNQILFGGNI
                     PTKVCKFCEQHSIQIYDFMKMNDVAILNAVATAEGAIAEAIKRSIINIHQSNCLVLGY
                     GRCAQILAKKLYALDANVCVGARNNDARSTANAFGYSSISLSQLDEKLLQFDYIFNTI
                     PECILTKERLEKVSQEVTIIDIASSPGGVDYSVVKEAGINATLCLGLPGKYSPKTSGE
                     ILVNAIENIINERRD"
     gene            complement(81025..82416)
                     /locus_tag="PC512_000206"
     CDS             complement(81025..82416)
                     /locus_tag="PC512_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HDF2439986.1"
                     /translation="MNYYELLRIKKERHKNKNFLIIDGEKYTYENILSYSEELGKQIS
                     LGENIPILIYSKNIMFQLISFFAINYSKNIPIICHYNLSKKVLDDILLKNNISIIISD
                     ESMDVIDLYDDNNNEVAKKVNFSIFNPKFNIYMYQYKNLINYLDKSICMGALSSGSTS
                     VPKVLYRTYESWAGFFPIQNGIFNISGESILFVNGTLSFTGNLNSIMSVLYEGGSIVI
                     SSGLNCKSWIRIIKQYNVTNIYLIPTKLQLLVKHLKEPVLKVVSIFTGSQLLFEDTAR
                     NLKKYMPKSEIILYYGASELNYITYLCYDELIEKPLSVGRPFPGIDIYIREGKIFVNT
                     EYAVYNATKPYSVNDIGYYDNDGYLIFEGRSDDILNIGGFKVSSTKIENEVKKIPQIE
                     DAIVLPYSDTIRGNQIVLFVITIDKITKKDLLIKMKDNLMKNEIPKKIIFLNSFPYTS
                     SEKIDRLALLKML"
     gene            complement(82420..83556)
                     /locus_tag="PC512_000207"
     CDS             complement(82420..83556)
                     /locus_tag="PC512_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiolase family protein"
                     /protein_id="HDF2439987.1"
                     /translation="MKEVFILGGLRSHIGLKNGIFQFVQPELLGASVLKDLIKKYEID
                     KIDEIICGNAVGTGGNIARLMTLTAGVSNEVPAFTVDMQCASAMMSIDIAFSKVKSGQ
                     CDLIIAGGFESSSLQPMRTYHKNDKRYNTNNPNYTVAQFSPDDNSQNSMLEGAERVAE
                     LYQIEKADLDFWVKESHKRAKEAREEKILEDIISPINNSTYDEGIRDKMSQRLLDRMP
                     SILGKETITNAANSCLINDGASFIIICSKKYLEHVKKKPKAKIINTCTIGTDATLSPT
                     SAIQAMDKLLEIESLNYLDVSAVEFNEAFAVIDVLFQRKYPELIDRYNIFGGALAYGH
                     PYGASGAIIALHLLKALEKTKGRYGICSIAAAGGLGSALLLERV"
     gene            complement(83588..84133)
                     /locus_tag="PC512_000208"
     CDS             complement(83588..84133)
                     /locus_tag="PC512_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HDF2439988.1"
                     /translation="MKNTKVNIQDLTKMSICVALLCISSYIYIPLPFTPAGVTAQTIM
                     INLIALILTPRQAFSTVGVYIMIGLIGIPVFGGGTSGIGKLLSPTGGFYFGFLFAALI
                     ISLLKGRNNDIKRYILITIFVGMPIIYFMGTVFMCYFNQMTVEAALFAAVVPFLIGDT
                     IKSVIASFLGTKLNNVLRRNL"
     gene            84457..85236
                     /locus_tag="PC512_000209"
     CDS             84457..85236
                     /locus_tag="PC512_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2439989.1"
                     /translation="MKVNENNINNIDEELDELSRKVYLESPDFWISISDKIIDKVFDE
                     MLLFFAVKYNYFNIVCFAIENNYLDLNMPSKNKKYTNIMEHLLDTSKQNEDKKIYNYL
                     LSLNKGNNLDERPILDELNCNISSDTFEKKDIYLPKYLCPSCNSNIFDTGYKVSNDIT
                     YKFSSKEAEPIEMCSEVSSIRCCNCDELLEDITLDKLYNLCKIQNCNNCGSNLTKVGI
                     IAKKKMNFDENTEKFKDVSTSYCCGNCDSEINLSQREHFKI"
     gene            complement(85691..86119)
                     /locus_tag="PC512_000210"
     CDS             complement(85691..86119)
                     /locus_tag="PC512_000210"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HDF2439990.1"
                     /translation="MIKKLNNKDINKIMEIWEKSTIKAHDFISKEYWQNNYNTVKNEY
                     IPISDTFVYDDGDEIKGFISIIDKSFIGALFIKPKYQNLGIGGKLLDYATKKYKSLSL
                     AVYKDNKKAVVFYNKKGFNIVKEQVNEDSGFKEYIMEYSK"
     repeat_region   86180..87908
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=86375..86403
                     /rpt_unit_seq="atttacataccacttagttaatataaaac"
     gene            complement(88092..88358)
                     /gene="cas2"
                     /locus_tag="PC512_000211"
     CDS             complement(88092..88358)
                     /gene="cas2"
                     /locus_tag="PC512_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endonuclease Cas2"
                     /protein_id="HDF2439991.1"
                     /translation="MFVIVTYDIVEARSLNRIRRILRKYLTWTQNSVFEGNITEGKLH
                     KCISEIENIIDNSEDSIYVYEIKNPNSIKKKCYGIDKYSDEMFI"
     gene            complement(88361..89341)
                     /gene="cas1b"
                     /locus_tag="PC512_000212"
     CDS             complement(88361..89341)
                     /gene="cas1b"
                     /locus_tag="PC512_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated endonuclease Cas1"
                     /protein_id="HDF2439992.1"
                     /translation="MYKDYYIISNGDIKRKENTIYYYNLEGEKKILPVEQVDDIHIYG
                     EVDLNTKLINYISKYGVMLHFYNYYGYYSGTYYPRKKNVSGFSLVCQSACYLDKNERL
                     YLAKSFVESASYHILRNMRYYKVDESLIDTIKDELNDLNDVKEISELMGKEGRIRKTY
                     YKSFNQILKDDFEFYKREKRPPKDPVNALMSFGNSIMYTNVLSEIYKTQLDPTISFLH
                     EPSTKRFSLSLDIAEIFKPIIIDTIIFSLINNKRINKNDFEYQDKICYLSEKGKKKFL
                     QEFENKMQTTIKHRNLNRKVSYRMFIRLECYKLIKHFINDERYKVLKVWW"
     gene            complement(89344..89895)
                     /gene="cas4"
                     /locus_tag="PC512_000213"
     CDS             complement(89344..89895)
                     /gene="cas4"
                     /locus_tag="PC512_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas4"
                     /protein_id="HDF2439993.1"
                     /translation="MWLKFTKEGDFVPIDLEVLKVQGVKINYYYVCKRKLWLFSKGIT
                     MEQNSSRVLSGKIVHEDSYKRMKNKEILIDDILKLDIIKDEYVKEVKISSKMKEADEM
                     QLYYYLYYLKNSMGIEKKGTINYVKEKKQEELILTEEKERIIENTLININEINMQLSP
                     PKIEKKHYCTKCAYYEFCFVKEE"
     gene            complement(89910..92231)
                     /locus_tag="PC512_000214"
     CDS             complement(89910..92231)
                     /locus_tag="PC512_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HDF2439994.1"
                     /translation="MLYAKSNPVETLREHTDELLKQMNVLRESYGKNINSLDFLEEEI
                     FWQLLDFVIEFHDIGKAFSPFQELIKSRMDTKINEPKIVTYLENNVGHNYLSPAFIDY
                     SYIDRKKNKELRAVLNQVIVYHHERDIFIDKDFKNLIQKILDEDLINKVYELQHEFKV
                     RYPIKTEKLSKVYLQSVEKRIDKNHKYYNLYIMLKGILHRLDHSASAHEVVECNNVIN
                     IGEQTENYLMKEFGSLREAQSFAKSNRNKNIILIASTGMGKTETALIWIDKDKAFFTL
                     PLRVSINALFDRAKNIVGVGESNDTFLGLLHSTAIDYLEESNQENSSEIVDLAKLLSC
                     KLTFSTIDQIFKFPFLYRGYEKVYSTLAYSKVVIDEIQAYSPEIAAVLVKGIEMIHKI
                     GGRFMIMTATMPTIYIDELKKRGVMNSNLAELTCNTEKIRHCVSIVENSIDENLGKII
                     QSGMNKKVLVIVNTVKSAVEKYELIEEIVKPKGIDVNLNLLHSMYIQEDRAKLEKYIK
                     EFANSDRNGIWITTQLVEASLDIDFDELHTENSTLDSLFQRFGRCYRSREYEENSPNI
                     FIYTEKATGIGSIYDKDIVEKGLELLKTFINGKECVKMKEKYKVEMVKILYSKESLEG
                     TAFEKRFTSALNILDTITPYSLGSKDAQNILRNIEGYTVIPEDIYNKIEETLIKDYEE
                     LGQELINAYSNDDRQLINKIKSKRKKARREIIKKTVNLPIYKAKQNVIDIQVKGLEDL
                     KILLYKYDIYENKHTKQIFGKGVLISNEIDQFI"
     gene            complement(92242..92943)
                     /gene="cas5b"
                     /locus_tag="PC512_000215"
     CDS             complement(92242..92943)
                     /gene="cas5b"
                     /locus_tag="PC512_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein Cas5"
                     /protein_id="HDF2439995.1"
                     /translation="MKVLKLDLFQETACYKKPFAMKITETYPLPPYSTINGLIHKILN
                     ATEYIPFNISVQGTYESIFNNYQTTYFYKKDSITSMPMNSHMLLNVNLIIHIGGDFDL
                     LEEIYDSLLNYDEHLSLGRKEDLVRINDIRFVEVNKFEVDEDIQLDDYENYKLSECNI
                     RMPIYIPKTSLQDTDIDGISYRLNNYYDNNAVEDKKRVWNKVDSYYVEDGNTISIGDI
                     LLDNEGDLLYFNNIN"
     gene            complement(92945..93859)
                     /gene="cas7i"
                     /locus_tag="PC512_000216"
     CDS             complement(92945..93859)
                     /gene="cas7i"
                     /locus_tag="PC512_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein
                     Cas7/Cst2/DevR"
                     /protein_id="HDF2439996.1"
                     /translation="MKRGLTFTVIAQAQSLNYGEGIGNISELKKLSRDDGNIYTFASR
                     QCLRYDIVRLAAELFNWNLQVVDKEKGTIQFKDNISIRESEEMDLFGYMKTNKKDEKD
                     KKGGSLTREATVRLSNAISLEPYRSDMDFLNNKGLADRIGEHPNLANIEQHLSYYTYT
                     VTIDLSKIGKDGDIELDNKEKCRRVVEFLEIIKVLNRNIRGRQENLSPLFVVGGVYEI
                     ANPFFLGRIKLKGDKNGFKINKQAIEEVIQGTFLGKDLKEFTYVGMVDGVFINKEEFK
                     GLFEDNFLSVDKFFGQLVKEVKEYYGVN"
     gene            complement(93861..95711)
                     /gene="cas8a1"
                     /locus_tag="PC512_000217"
     CDS             complement(93861..95711)
                     /gene="cas8a1"
                     /locus_tag="PC512_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein Cas8b1/Cst1"
                     /protein_id="HDF2439997.1"
                     /translation="MKLRVYRGDWFFNMGIVGFLNIIKKADKQAEIFIMEDYIEFDSL
                     FLENFHEYYFNYFMDEYDVSKRIKKNIDYSINFIKSKPDRIKDGIKKIKDSVKQQNDK
                     IKKFDEEKFNMIKEKLDSMSKIKSYDEFDSLEALVDETIDIFKIKSINDRLTANLYKY
                     VVQDNYFGQVSFFNVAKAKLDLDGLKQVMFNDYLRQIIYFGELEDLLEENDYDKLKNY
                     LNDRLNSIAKDINEKKVSKSSINTIEKIMKEINKNFIKKNKSIEDIKKYMDSLEVCEM
                     CGLYKGILDEYSESNFAPLGVSTNNARNMFWNQAYVPSICDICKLILFCTPAGATYTR
                     KNYLINEENEFYLFVNMDTCINELFERNNSLKAQKSEYSDSKDENPFNQLIKSIVEEN
                     TLKSEWQLRNILFVEFKASIDSKKCKINYFNIPTYLAKFFVKENKKIQSIYDYKLKSN
                     VLDLILKSKDLKHLINNTLRNIVKSNLESNNKSNISGLSCFNVVQLRTILNNYKRGVY
                     KMDYKKLRKIYESGCEIHDYYIDKNAKNKIEGITYKILNLIKVGNKNDFMQTILRIFS
                     PSEKTPPEEILQIFVEEDLDFESVGYAFVTGLISGKYEGKDKLPNEKEEK"
     gene            complement(95717..96454)
                     /gene="cas6"
                     /locus_tag="PC512_000218"
     CDS             complement(95717..96454)
                     /gene="cas6"
                     /locus_tag="PC512_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endoribonuclease Cas6"
                     /protein_id="HDF2439998.1"
                     /translation="MKMKIEFSTGCIPISYNSLFMSIIKEAIRKSNEDYYKNMYYYKE
                     KNNKKTKNFTFSVYIKKYSIEGDNFIIEDKVILNISTPDLELGFHIYNGLMTSKKCLY
                     KDYELTRIRIDLSREKKVTEERVLFNALSPICVKSKEGKFLEITDDRYIEELNYITNE
                     VVKNYRGNGLKRKLEFENIGLKKVVVKESLREFKKITGKEYQYINGYKGKFILKGDID
                     DLNLIYNLGIGFRRAQGFGDVDILEWR"
     gene            complement(96532..97449)
                     /locus_tag="PC512_000219"
     CDS             complement(96532..97449)
                     /locus_tag="PC512_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HDF2439999.1"
                     /translation="MMILIQSRGKMKCKELSEELEVSERQIKSYKMYLEQAGIFINST
                     PGIYGGYEIDKCNSISLIKLLDSEVSILDMINSQLEYNNDIYKNEFNNIVEKIKAVLN
                     TGEKSDTYMDYFTVQAQRNCDYESEKNKCNEIIRAYTTKHKFWIEYYSLNSGNSERIV
                     HPYGLFNYKSDTYMVAFCEKRFKFIDFKLCRIKDYKVLEEKYNVDKSFSWDEYSKNSI
                     GIYKGEEINVVIKISHPFSTIIKEKVWVNNQQIIEYDDKSIMFKAKMRGYEEIKSWIL
                     SMGAYVEVVEPDRLRNDILLEIEKMKKIY"
     gene            complement(97728..99644)
                     /locus_tag="PC512_000220"
     CDS             complement(97728..99644)
                     /locus_tag="PC512_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2440000.1"
                     /translation="MNIKQFAINNISRNIKAYLGYLASIVISSSLLFSFIMFTSHPDL
                     DVSQFPDYLKEGLKMSKIIAYLFLFFFVFYSVSVFLKSRYKEFGILYITGISKRQVMK
                     LIFIENMIINIVSSVIGIIIGLIFAKIFLVVMSTFLELSPLKFYIPFNAILSTLIYFM
                     ILAVLTSIFTSFIVKENQVLKLLKGTKTPKPEPKTSLMLAILSICLFIIAYYNAITST
                     DQYTTYLRLVPVTSLTIVATYLFFSQFSVFFMKKLKLNKRFYRKNTNMLWISNLIYKV
                     KDNARIFFLITITSAVAFTAIGTVYSFWKDVERQINLIYPNTIYYSTMTLHNDPKKPD
                     SKEKDKERMMFIENNLKKENVDYTRINGEFKTVFPKKSDFNVRIMKESKYLEITETIG
                     VKPISFEDNECISLLSSSLPGNKNVKENIIVGNRGLKVAKQVEECVMPAYYKNMYVVK
                     DNFYDSIESKFIVDRFTAFEVEDSSKTIEICREFENKFNNESGMQPYLFFSKELMIGT
                     GKLMYSTFIFLAIFIGLIFFVTTSSFLYNKFYMDCQVDKKKYEQLNKLGMTYNEIKKA
                     STIEIGIVFLFPYVVAVIHSIFALTALKNSFDIEVASSAVLVMGSLFLVQIVYFLIVR
                     NNYLKEIRLNLVNF"
     gene            complement(99644..100390)
                     /locus_tag="PC512_000221"
     CDS             complement(99644..100390)
                     /locus_tag="PC512_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001637630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2440001.1"
                     /translation="MKILTVNNLSKVYGKKIIFNALNDINFSIEDGEFVGIMGPSGSG
                     KTTLLNMISTIDKPTTGTMELKGKNPLLLRGEELALFRRRELGFVFQDFNLLDTLTIG
                     ENIVLPLTLDKVSVKEQDERLNEVSTILGIKDLLGKRTFEVSGGQAQRTAIARALINN
                     PSILLADEPTGNLDSKSSKVVMELFQKINKENKVTTMMVTHDPLAASYCSRILFIKDG
                     SIYNEIYKGSSREQFYQEIMDVLTLLGGDN"
     gene            complement(100494..101345)
                     /locus_tag="PC512_000222"
     CDS             complement(100494..101345)
                     /locus_tag="PC512_000222"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HDF2440002.1"
                     /translation="MSLDVIFILKSVIIAIVEGLTEFIPVSSTGHMILVGNLIDFKGQ
                     FAEMFEVVIQLGAILAVVVLYWKKIKDSVIEFFKFIFTGGKEGKIGFRFGMNVIIGCI
                     PFAIIGVLFYDNIKSLFNLQSVIIGFIVGGILLLVVETLFRKKNHSTDNIDKITPIQA
                     LKVGTLQVLSAWPGMSRSASTIMGGWIAGLNSPTAAEFSFFLAVPAMVASSGKDLFEF
                     DYSIMTPTLWIALVVGFIVAFIVSIIVMEKFVNFLKKKPMRVFAVYRIIMGVVLAVLA
                     FTNIISV"
     gene            complement(101593..102597)
                     /locus_tag="PC512_000223"
     CDS             complement(101593..102597)
                     /locus_tag="PC512_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2440003.1"
                     /translation="MKLFLKDYKGYIFIYYIGIVMTIIYCNLMKFISFGESLYILLFS
                     SFILLCFLIYKYYKNREVYNLFEKGVHSLEESFLYLGSSFLGRNISVILKQQHKLYQS
                     MIQEHKKIHSEHLTFINQWIHQMKTPISVISLQLQDYEGEEVTENIRKEIDRLNKGLD
                     MAMHFARADNFQKDFIVEKAKLNEIVSSIVNEEKRLFIKSGMIPKIQVDKFTYVYTDV
                     KWMKFIIGQLITNGVKYSKDYSNYLTIKSEENNKYVILSIIDEGIGIVSKDLKRVFAP
                     FFTGENGRKFGESTGMGLYLVKKVCDDLGHKVSIKSEVGKGTEVSIYFNKGVNSLIKM
                     "
     gene            complement(102607..103299)
                     /locus_tag="PC512_000224"
     CDS             complement(102607..103299)
                     /locus_tag="PC512_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011987369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2440004.1"
                     /translation="MSYKVYIVEDDISISTLLKDYIEKYGFEVIVEENFDDIMITFES
                     FKPHLVLLDVNLPKFDGFYWCRCIRQQSNLPIIFISARDGNVDQIRALESGADDYITK
                     PFYYDVVMAKIKSHIRRVYGEYSPKIDERIVELDGLKFYPERLELELNGENLIITKKE
                     GILIECLIKRYPKVVSRDYLLEKIWDDIEFVEENTLNVNVSRIRKRFEELGIDNAVQT
                     VRGLGYKLNKNW"
     gene            complement(103613..104572)
                     /locus_tag="PC512_000225"
     CDS             complement(103613..104572)
                     /locus_tag="PC512_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NrtA/SsuA/CpmA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF2440005.1"
                     /translation="MKLKKLLIGITILTLATASLAGCAKKNNGEKLSEINLTYVKSPL
                     NVPSIIQKQDDLFGKEFKKDNIKVNFHEITTGPEQTQALAAGEIDFLHALGGTSALIA
                     ASNGVELKILNTYSRSPKGFMILTNNNSIKSAADLVGKKVAGPKGTILHQVLISALDK
                     EGLSMDDVEFVNMGIPEASAALSDGSVDAALIAGPAALKAMKSGSKLVANGEGLVDGI
                     IVTAVSTDFAEKHPEIVERFMKVEKETLEYVNNNFDEAMEKVAKEVDLSLEETKELYA
                     WYDFSLDITDKDISSLEDTQDFLIKNKLQEKKVNIKELIYNAK"
     gene            complement(104605..105483)
                     /locus_tag="PC512_000226"
     CDS             complement(104605..105483)
                     /locus_tag="PC512_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2440006.1"
                     /translation="MNNLVCDSGYIIRNLYKSYKVDNKEHVVLSDISLNIDRNHITVI
                     LGESGCGKTTLLRAIASLEGINSGEIRFINDNKEYRPNVGFVFQESRLMPWLNVSENI
                     AFHNQRKNTILNKVLRKFKHNKRIRSKIINDNFRSLETNDNLNKSNKYNRKSNIDVEK
                     YLKMMNLQKFKNSYPNELSGGMAQRVSIARALSFNPDMLLMDEPFSALDYFTRIDMQN
                     EVIRIHKSTNKGVIFVTHDIDEALKIGKKIVVFTDERKVKEFNIEDGYNRDLTSDYYI
                     KLKKDILMTMKSNKGI"
     gene            complement(105476..106258)
                     /locus_tag="PC512_000227"
     CDS             complement(105476..106258)
                     /locus_tag="PC512_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2440007.1"
                     /translation="MVNKFNNKFLRLVKSVLIFFIILLLWKITNYLGIWSDYILPSPE
                     KVYSTFLNMISDGSIFINVYASMKRVLIGFAISTAIGVPLGIFFGIYSGVYEYFKSLI
                     NFLRNTPPLALIPMLILWFGIGEESKIIIIVLASFFPIFTSTLKGIKNCDSKLIEVGR
                     VFEFSKLQIIFKIIIPNAILDIAVGLKLALGYSFRAIIGAELVAASSGLGYLISDGKE
                     MSRTDVVIVGIIVIGLLGIITDYIFSIIVKKVSKGKMVEAYE"
     gene            complement(106259..106888)
                     /locus_tag="PC512_000228"
     CDS             complement(106259..106888)
                     /locus_tag="PC512_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440008.1"
                     /translation="MNKYLLINPVAERMYGEKFHLIKANLIKKGYIITECEPQLEYVK
                     KQYKEYTKKTENTMLDCRCPESISLLKRNNLINNFEVPMIEPILVRTCRVLYDKYIKS
                     KDDMLVVTCPCTQLRDFASEKFKDKGNAMFYTWKEFAEQEGVKSLGKIDESPIPLGYF
                     KDTFEKVLEVSSEDEILSEIQKIRNGFEDKYDIVEMFYCKDGCNNGDGL"
BASE COUNT        35653 a        18413 c        11744 g        41263 t
ORIGIN      
        1 ttatttttta ttacctctat attattgtat tacttaaaaa tacataattt aactcttatt
       61 taataacaga aactcccata tatggtctta aaacttcagg aacaaccaca gaaccatctt
      121 cttgttgata attttctaat atagctgcaa cacttcttcc aatagctaac ccagagccat
      181 ttaatgtgtg tacatattca gctttagaat ctttatctct tttaaatctt attcctgctc
      241 ttctagcttg gaaatcttcg cagtttgaac aagatgaaat ctcaacatac ctattgtaac
      301 ttggcatcca aacttctaca tcatatttaa aagaagccgt aaatcctaaa tcacctgtac
      361 atatctttac tactctataa ggcagattca ataattgtag catagtttcc gcattgttag
      421 taagcttttc taactcattg taagattctt ctggtgcaac tattttaacc atttctactt
      481 tgttaaactg atgctgtctt actaaacctc ttgtatctct tccagcagaa ccagcttctg
      541 acctaaaaca tggagtataa gctgtataat ttatcggtaa ttgttcaaat ttaagtattt
      601 cattagcatg tatattagtt aaaggaactt ctgatgttgg aatcataaaa tagtccatac
      661 cttctatttt aaacatatct tcttcaaact taggtaactg tcctgtacct aaaaaactat
      721 ttctatttgc cataaatggt ggaataactt ctgtatatcc atttactttt gtattcgtgt
      781 ctaagtaaaa atttaataat gctctctcta atctagcacc taatcctttg taaagagtaa
      841 atcttgaacc agttatttta ctagctgttt caaaatcaag tatacctaat tctgttccaa
      901 tttcccaatg agccttagat tcaaaatcaa aggtagtagt ctttccccaa gttcttactt
      961 caacattatc ttcatcagtt tcaccttgtg gtacttctgg atgtggtaca tttggtattc
     1021 tcattaatag gtattccatc ttatcttcta cttctttaag attttggtct attaccttaa
     1081 ttttatcaga taactctttt aatttaatct tttcattttc tacatcttta ccttctttta
     1141 taagatttgg tatattttta gatgctgtat ttaattcatt tttcataact tcaacttctt
     1201 gaagagtctt tcttctttca tcatctaact taactacttc atcaaggtta aagttttttt
     1261 cgccccttct ttccattgct ttttttatac aatctaaatt ttctcttatt ctttttatat
     1321 caagcatttt ttcctcctca gtacctaaga ttggatttat ctcttaatct caaataactt
     1381 agataatata ctttatgctt gaggttaaga aacctttttc tttatccgaa cctgttattt
     1441 ttattttatt tatattttac tcactttttt gcccattgtc aaattatatt taattaaata
     1501 aatgaaattt aattttagga gaatattgct agatttaact tcattataat tatatctatt
     1561 ttgctaatca attatctatt ttgacttttt ctttatcaat cttgtatagt tattaacttt
     1621 tatataaatt tttttatatt ataacatagt cctatatatc tattatttgg atagaattat
     1681 tttttaaatt agaattattt tgatgaatga ttcaagtaat aggtatgaaa ttgaatcttt
     1741 tagaactgct tacaaaaaat actcaaagaa aaatagtaat tttctcagat tcacaatata
     1801 ttttatatga aatgttataa gttaatctat ttaataaatt taaatttgct attatagatt
     1861 tagttccaaa gtcttactgc aaagtaatat acatagtttt ttaataaact aataagtgca
     1921 attaataact acttaattgt ttaatatagt acatagataa ctttaataaa tctacagtta
     1981 tttaaaaagg tagaatcaat aaaattatac ttataaatct tcaatacaat aattaaaatt
     2041 taataaaaat ataattgttg atttaactgt aatcttattt aattctacct aacttattat
     2101 ataaaactat tttttataga ttataaaata tctaactttc atctacttca aagaatacaa
     2161 tacttctcct tctcttatag tctgcaatac tttaatatct tttattttca tagggtcgat
     2221 tgtaagtggg ttttcatcta atattatcaa attagctaat ttcccttctt taattgaacc
     2281 ttttttatct tcttcaaaat attgatatgc tgcatttata gtaacaccct ttaaagcatc
     2341 taatgggctt atcttttcat tttctcctat ttgtatacct ttttttgtaa ttctattgac
     2401 agcacaccat actgtttcca gcatattagg tgctattact ggtgtatcct gatgaagagt
     2461 gtaaattaat cccttttcta tagttgtttt aagtgggcta atcttaaacg ctctatcttc
     2521 tccaaggttt ttgatatgaa tatcacccca ataatatgtg tgagctacaa aatatgaagg
     2581 tatcatattt attactttca tatcatcaat ctggtctgct cttactgttt gagcatgtat
     2641 cataactggt cttatattat tttcactact ttgctctttt aagtttaaaa ctttctcaaa
     2701 cgcatctatc aactggtctg ctgctgcatc tccattacaa tgagttaaga gttgcatctt
     2761 ttcttttagt gaaatatcta taaacttttc tacttcttca tctttgtata taggatatcc
     2821 acaataacca tcatctgaat tttcatatgg tctactcaac catgctgtct taccttgtgg
     2881 agaaccatct aagaaaatct tataacctcc tattttaaat ctatttatat atttttttat
     2941 aaactcccta ttattatctg ctacagactt actttttttc aaatttacat atcctacaac
     3001 atccattttt aatttatttt gatttgccat tgcttttaaa atgttaaatt gattttcttc
     3061 cattaaacct tcttgagctg ttgtaatacc atagcttaga tatatgttct gtgctttttc
     3121 aattgaatta aaaatctcat ttgatgatgg ttgttttatt ttagatgcta cattaaaaaa
     3181 tgcattttct tctaaatatc catttggttc ttcactgcct tctactctac ctatatgtcc
     3241 accttctggg tcacgtgttt cattggtaac accaagctgt tttaacccca atgtatttgc
     3301 aactcccata tgaccagaag catgtgaaat tagtattgga ttttctgaag atgcactatc
     3361 gagtacactc ttatctggat gcttattttc ttctaaaaaa ttattatcat atgaaaatcc
     3421 aattatccag tctccttttt ttatattatt cgactctttg aaatcctgta ttttttttac
     3481 tatgtcttta aaactggttg catcttctaa aggaactagc tttagagtag tagcaaaagc
     3541 tatcaagtga ctatgtgaat ctataaaaga tggcatcaat gtcttacctt gtaaatctat
     3601 aatttctgta tctttatttt tcaaagcaaa tacttcttct tttgttccta tcttttttat
     3661 tattttgtct tttataagaa tagcatctcc acatattgaa tcttccattg tgatgatatt
     3721 tccattgtaa taaatttttg ctttcataaa attctcctta cgttgtctac tttaataaat
     3781 ttttttcatt attttctgct taattatatt atcttcttta taaacttttt ctttagagtt
     3841 taatcatata aaagttttat ttttaattat tgtttgccaa gaagtaaata ctattcattg
     3901 taaataagac aaattaatag gctttatact aattgaaaaa atattataag ttgttaaatt
     3961 taaatatcta aactcaatta tatctgtaca attgtaattt tttaaatcat gatgtattat
     4021 tttaaatata cagttacatt attattcaca atataagtat cttagttctc aaataacatc
     4081 tcatgtaatc tattcaatgc aaaaaattta aatatttttt aggaggtttt ttatgagcaa
     4141 ggaaaataaa aatgtaagaa ttgctgttgt ccaggcgtca ccagtcataa tggatttaga
     4201 aaaaactgtt gaaaaagcat taggattaat taaagaagct ggtagaaaag gggcaaatat
     4261 cgtagttttc cctgaagcat tcatacctgc atatccaaga ggtctttcat ttggatttgt
     4321 tgttggaagt agaacaatgg aaggtagaga agattggaaa agatactatg ataattctgt
     4381 accagttcct agtgctacaa cagatttatt aggaaaagca gcacaagaag caggagtata
     4441 tctatcaatg ggtataacag aaagagatgg taatgatata aattgtaccc tttattgcac
     4501 aaacttattt ttctctccag aaggtaagct aattggtaaa cacagaaaac ttaaacctac
     4561 aggaacagaa agatgtattt ggggagaagg agatggaagt actcttacag tagttgatac
     4621 tccatatgga aaaatgggtt cgttgatttg ttgggaaaat tatatgccat tagctagaac
     4681 agctctttat gctaagggtg taaaacttta catagcccct actgcagatt caagagaaga
     4741 gtggcaagca actatgaaac atattgcttt agaaggaaga tgttttgtaa ttggatgcaa
     4801 tcaatatgtt gaaaaaaata cgtacccaac tgaccttaac tactataagg agctagatgc
     4861 agaaccagaa attatgtgtc caggaggaag ttgtatagtt gacccttttg gaaaatatgt
     4921 agcaggtcct attttcaata aagaagaaat gctaatagct gatttagacc tagaaaaaat
     4981 agtacttagt agactagatt ttgattcaga aggtcactat tcaagaccag atgtatttga
     5041 attaattgtt catgaataat ctttttacac aaacatctac ataaatcttt ttacataaaa
     5101 aaatgagata ctcataagta aatttcaagt atctcatttt tgcttaaaac ctataatcct
     5161 aattataaat ttattcacct atattttttc taaatcaact actgttcttc caacatgttt
     5221 tcctgccatt attgaatcta tactatcatt taactcttcc aatgatacta catttaccat
     5281 atcatctaaa tcatctaatt tccattcatt tgataataaa tcccatattt ttaatcttaa
     5341 gttcattggg caatccacag aatctatacc atataaagta attcccttta agataaatgg
     5401 atatactgaa cttgtaaaat caactcctcc tgcattacca caagttgtta ctgctccaca
     5461 ataattagtt gtctttattg ctgttgctag agtatttcct cctactgtat ctattactcc
     5521 agcccatctt ggtctaagca gaggtcttcc tgagttatca tccacttctg acctatgtat
     5581 aacatcttta acacctaagt ttagtaatac ttctttttgt tcttctaatt ttcctgttga
     5641 aactacaact gaataaccta atttaatcaa tattttagtt gcaattacag caactcctcc
     5701 agtaccacca gtgactaata catctcccat attcttgtct acagaatcta taaatttata
     5761 cacagataaa gctgctgtaa accctgctgt accataatcc attgcttctt ttagtgaaag
     5821 atttttagga agtttaacta cccaactaga aggaactctt atgtattctg aaaaaccacc
     5881 agaagtattc attcccaagt cataacctgt tactaaaact tcttctccaa ttttaaaatc
     5941 atcacaacta ctagattcta ctataccaga tgcatcaatt cctggtgtat gaggatactt
     6001 tctcgtaaca cccttattac catttgcaga aagtgcatcc ttgtaattta aagaagaata
     6061 ttttactttt attaaaactt cgccttctgg caatgtatcc acttctcttt caactatatt
     6121 tcttctaaaa tttccttctt cttctgtaat atatagtgat ttaaattttt tattcataaa
     6181 tttcctccca atacatttag ttttatgtta aactaattat agtttataaa tagttttatg
     6241 tcaaactaat ttaaatagat taaagattgg agaataattt atggaagata aatatattgt
     6301 acatttcata agtaaaacaa aggctagtat gattaaattc attgaaaata aactcagtaa
     6361 aaatggttta ggtgagttaa tacctactca tggaaatatt ttaactgcac tttatgaaaa
     6421 taatggaata cttacaatga aagaaattgc agctaaaata ggaaaagata aatccactgt
     6481 tacagtgttg gttaataaac ttataaacct aggatattta gaaagacaaa aatgtacaaa
     6541 tgacaaacgt atcacgtata taaagcttac aaaaaaggca ctgcttatag aagatacttt
     6601 taatagcatc tcaacacaag ttaaagagac ggcatatcat aatattacag aaaatgagaa
     6661 acaagaattt cttagaattt taaaaaaaat taatgataat tttaaaaatg ctgactaaat
     6721 tgagcataat tatatctcct attggaataa taaataaaaa gaatcaaata ttgtaaaaat
     6781 ttattgtgat agagaggtag aatatgaatt taaaagatag taaaactaaa gaaaatttat
     6841 taagagcttt tgcaggtgag agtcaagcta gaaatagata caatatttct gcatctgtag
     6901 caaaaaaaga aggattatat ataatagagt ctttatttaa ttacactgct gaccaagaaa
     6961 aatcacatgc aaaacaattc ttttctaaat taaaagaatt tgctggtgaa aatataagta
     7021 tatcaggagc ataccctgta gatttatatg acaagacagc acaacacctt aaagctgcac
     7081 aacataatga gcttcaagag tgggatgatg tatataaaaa ctttggaaaa acagcacgtg
     7141 aagaaggatt tgaatctata gctaagttat ttgaaaatat agctgaaata gaaaaagttc
     7201 atggtgatag atttggtaga tatgctactg atttagaaga aggtacttta ttcagaagaa
     7261 atgaagatat acaatggata tgtacacatt gtggccatat acatataggt aaagaagctc
     7321 caaaagcttg tcctgtatgt cttcatccac aaggatattt cttagatttt aaaaactcat
     7381 tatttgaata aattaaggca ataattctat ttaaacaatt tactatattt atatcaagta
     7441 tttttataaa tactgtatta tcttaataac aataaaatga accattgata ttactataag
     7501 tagaaaatgt agtttaaata caatttatag taattcatca tggttcattt tattgtttac
     7561 taatccctat aacctactta aatctatctt taacttttac atactcacat aaaatcttat
     7621 ctttaaacta aatatttaaa taaagtgtat tttaagtata ttattataat acattatata
     7681 agataataca ctatgataac tttatactta tatcatttat ttcttttgtc aagtcaatct
     7741 caataatctt aactacatct ttttcaaact ttactttttt ataatccaga catcctacta
     7801 cgaatggaac tccaaacttt ctaaacaaat aaatctttcc actttcattg tatattgatg
     7861 taaaattttc ttctattata ttcactatca attttaactc ttcaaaagtt attatagatt
     7921 taactaaaaa cttctctatt atgctcaata taagcagttc ttttttacct atgctttgct
     7981 cttttttata taaattttga aatatttctt tggtataatt acatataact tctttactga
     8041 gaataaaatc aatgtcaaat tctttattaa tatccttttt cataaacata tttgcaatat
     8101 catcaagaga agtctcttct ttcatagaca atattaactc tattctttct agtattttat
     8161 ctcttggaaa gaaagtctct tgacctgtaa aagctgattt ttttataaac cattcctctg
     8221 gtattatgtt ttttcttttc catctatata attgaccata agatatatta gttttgctca
     8281 ataaatcttt cttagatatt aattcttcca taacttttct agcccacctt tatactgttt
     8341 tttacagtag aattatctga aactgataaa ttatcactgt attcaatatt tccaacatca
     8401 caattatcta ctagagatat gcttttacct cgtatatctt ttattgatgc atcttctaat
     8461 tcaatagtat ctccctctat caaattacat ttaaactttc ctgaaaaaat attaatgatt
     8521 ttaattaatg aaaaagcatc tttgcttctt cctattttta tattagttgc ccctatctct
     8581 ttacaataag aacctcctcc tgaataaaca tatatatttt ctccatttaa aagaccatca
     8641 cattttattg ctccatatac ctttatatct tcacattcta tatttgattt atttctcatt
     8701 tcgccataga tttttatatc ttgtgcatac atattttcat ttacacttaa ttgtcctctt
     8761 attgtaacat tattacattt aagtttgcca tccactttct gttgagcagt tataactaag
     8821 tcatctattt ctgcatctcc ctctatatta agttgaccat tcactcttac acgctctgct
     8881 ttaagattgc ctcttataat agtttttccg ttaacaacaa aattttttat attgatgtca
     8941 ccttcaaatt ttgcatctcc aagaactttt acttcgttac ttttaacatt tccttttgat
     9001 ttagagcttc ccacgatttt tatattttca tactcaccac tacttataaa gccttctcca
     9061 agtattttta tagacccttt ttccatatta ttacctcatt ttaaatttta tttttaaacc
     9121 tacttattac ttatccttct ttaattttat tttttcactt atattcttta tttcaccaac
     9181 tattgaatct tcatcaatct ctatactttc actgtactcc aaactttcta cataacatcc
     9241 cttgcctatt ttaatatttt ttcctcttac aactttgact tcactatttt ctaagcttat
     9301 ttcatctgct tctataatat ttgcaaacaa tttactttct gtatactttc taattgataa
     9361 tagacctaaa cttatcaaat ttgaagacac tttttcaaag ttgatatgct ttttttctag
     9421 catacgaaat tttttgcaat aatctccatg cccctttttt atatttatac tacttgctcc
     9481 aacttcatta aaattagaag ttccatttaa actaatatta acttcttcac aattcaaaaa
     9541 tccattacac tccaagattc cacttaaatt gatattttca caatctatat tctcatttgc
     9601 ttttaaatat ccttctccat gaataatatc agattttata cttccttcta cattaataat
     9661 tccactagta tcaatttcaa cagaattaat atttcctgta catctaagaa gtcccgatat
     9721 ctcaactttt gatgccagta tgtttccttc tactttactt aaaccagatg taaaaaattc
     9781 attacattct gttgtcccaa aaacttttgc tgaaccagaa gaatcaaatt tactacattt
     9841 tacacttcct tctattttgc ctgttcctga tatattaaca ttatcaaaaa ttccaccttt
     9901 acattttcca acaccatcaa atcttagtga acttaattct tcattcataa tgatatcctt
     9961 tctttaccgt attttatctt taaacctaat ataacaaaac attgttacgt tgtcaagtat
    10021 gataataata cttaataaag caactatcat ttattttcta taaataggca taaaaataat
    10081 agggaaatgc tttatttaaa ctataaatct aatttcttag attgtggttt aaataaaata
    10141 tatccctatt actcaatctt tatatattca ttgtataaac ttctaaaata taagtcttta
    10201 aattctactg tcaatacttt ttatacactg tttgtgctat catctcacac acctaaagga
    10261 gtgggctttc cacactattc tgtaacctac aagacactat cttcttctat ctattgataa
    10321 atttttctat tacatcagct agtctctcca tatcagttgg ataaacttca cctatgctac
    10381 ctattctaaa tgtatctata tcagtcaatt tacctggata gataacaaat ccattatctt
    10441 ttaaataagt ataaaattcc ataaattcaa actttgcatt tttaggatat aagaaagttg
    10501 ttattacagg tgattgagca ttatcattca ccaaagtatc aaatcctaaa gattttaatc
    10561 ttgaagctat tgtaaactga ttttctttat atctagcata tcttttttca acagaacctt
    10621 cttcttccaa ttctaataaa gcttgataaa aagctcttac aacatgtgta ggtgaggtaa
    10681 atctccattt accattattt ttctccatag tctcccattg cgcatacaca tcaagagata
    10741 atgatttagc tataccttta catttagata atttctcttt attagctatt ataaaaccaa
    10801 atccaggtac tccttgtata catttgttag aactactaac taaaaaatct atattaaaat
    10861 cttcaacatc aatctcaatt cccccaaaac tactcatagc atcaactata taaattttgt
    10921 tatattcttt tgcaagtttc cctacctctt gtataggatt taatctacct gtagtagttt
    10981 cacagtgaac cattgatata tgtgttatat ccttgttttc ttttaataaa ttttctacta
    11041 catttaaatc cactgcttct atatctttaa aagtgcagtc aacaaattgt atgttaagat
    11101 aattacatat atctttcatt ctctttccgt atgctccatt tgcaattaca agaagtttac
    11161 catcttttga aatagtactt cctattatag cttctactga aaaagtccca cttccttgca
    11221 ttaatacact tgtgtattta tctgtatttt gggttgctag agatactaat cttcttctaa
    11281 catcttgtac taggttatta tattcaacat cccaagtaca ccaatctttt aacatagatg
    11341 ctcttactga tttagtagta gatagtggtc ctggtgtaag taatatgtaa tcattttctg
    11401 gtacaaaatc tgatttaata gtttcattct ctatttttat tagtatatct tctaactcag
    11461 ccatagtttc tattacaaaa tgtgctcctg cctctttaaa tttctttgaa actatactca
    11521 tcttagcttt taattcttcc ttatccatgt tctctacttc ttcttgtgta agccctaact
    11581 cacttgaacc ttttattaca gcaacactcc acattcctgc atttacgcct tcttttacat
    11641 cacttattgt atctcctact tttaccatag aactcatagg agacacccct aaagcttcag
    11701 catttttata gcacatccaa ggatatggtc ttccttgaga tacttctgat ggtgttacaa
    11761 gaaaatcggg tgagtatcct ttctttgctg catttggttc aactatgttc atcatctctc
    11821 ttgtataacc cgttgtagaa cctattttta atccattttt tctcaacttt tcaatagttt
    11881 caacaacatg aggaattgga gtcgtatact cttctaatgt ctcaaataac attggctcaa
    11941 attcagcata aagttcattt acatcatctt cagttggcac tttaccaaac ttatctgacc
    12001 aaatattctt tattctatcc atttcacaca tttctcttat atggtctatt tttaattttc
    12061 ccataggttt tcttgcttct tccattgtta catctatacc tcttctttta aatatctcta
    12121 taaatacatt aagaggtgca aaacatccat aatctactgt tgttccagcc caatcgaata
    12181 ctactgcttt tattttttct ccatatatct ttttcatatt tatagcctcc atagattctt
    12241 tttagaattt ttgtgttttt aattgttttt acttttaaag tataactttc atatgttaat
    12301 tatacatcat atttaggtta aatatatatt aaatttctgt ttttagttgt atttagttgt
    12361 ttttattttg tatcatattc ccataaaatc ctaagttaca atctaaaatt tactttctaa
    12421 tcttaatcta tgaactgact atattttatg aatttagttg tattgagcat agttgtatta
    12481 tataaaacta agggtttatt ttgcttctat ccatgttata tttatctcat ttaacttatc
    12541 cttccattca ttcggaggtt ctacatcaca aataacaaaa tctaattcct ctaaatctgc
    12601 tatcttatac atactagcaa ttcctatttt agaactatca cataatacaa aactttcctt
    12661 tgaatttttt atatatgctt ttgacaacaa tgccttattt tggtctatac tactaattcc
    12721 aaaactatca agtatacctt cactagatat aaaagcttta tctacgtata agtttttcat
    12781 agcatctatt gatattggac atgctgtcct ttggtgtttt aaatttactt ttccaccaat
    12841 aaatataact tctccatcaa acaaaccttg attctcgtaa gaaatcaatt ttgacagaac
    12901 tggataagag tttgtaataa tttttaaatt gtttacagat attatataat ctacaatctg
    12961 caaattggta gtaccttcat ctatgataat tgactcattg tcatttacaa acttagctgc
    13021 atatttagca atactttgct ttttatctag gttagtattg tttctcttta tatgttctgg
    13081 ttcaatcact ccataattta tttttatagc accaccatat acctttttta atttattttc
    13141 attttctaat tcttccaaat atcttcttat tgtttctgat gatacttcta atctttttac
    13201 taattcttta gtgtttacct tcccttttga atctagtaat ttaagtattt ctttttttct
    13261 atctatcgaa tttaaagaca ttcattttcc tcctaaatat aatatatttt tctcctataa
    13321 tattacaatg atacctaaga tttatgaaat catatttatg tattaaattt tttacttaat
    13381 taaagttatt ttcaaaagac tttgtattat cattaaaaaa gtccatcaaa tattagtatc
    13441 agatggactt tgtaaaattt tattttataa attaatattt aaagtctaac tactaattta
    13501 ttttcttgtc tccaagaatt ttactaaatt atttacagta gacatatctt ttctctctaa
    13561 atcagttggt tgaagctcta tccctaatct attttcaatt tcaagtaaaa cttcaattat
    13621 agctaatgag tctaaaagtt ccgtctcaaa taaattaagg tctaaatctt ctcttatctc
    13681 atcagtccct aatacatctt caaatatttc tataactgtt tcttgcataa attttcctcc
    13741 ttaaaattaa gctaaataac ctgagaatat cagcaatcca aaacacacaa tatggaatgt
    13801 aatgaaaatc tgcactctct cgaaccattt atctttttta tgttttttat aaaatttaga
    13861 ttttcgctga tatatatcag ttaacacaag tgccaatcct tggtatacac cataagcaac
    13921 ataataccaa gttagaccat gccaaaatcc cattgttatc atggttatca tctgagccac
    13981 atgagcagca gtagtccttt tcttaaatct tttctttctc attgatgaca taacaaatct
    14041 agaaaaaata taatctccaa accatcttga aagacttata tgccatcttg tccagaactc
    14101 tttcatatct ttgctgataa atggcttgtc aaagtttata ggtacttgta ttccaaatat
    14161 gtaccctgta cctatagcaa ataaactata tcctgcaaaa tcaaagaaca ggtataaact
    14221 atatgcgtac atataactta aaatatttat aaaactcata tctttaggta ttcttgatac
    14281 ccaatatgta tttatcaaaa atgctataac aaacttataa cctactccca tgacaatatt
    14341 ttttattcct ggcagtaagt attcttctat atactctttt ctagagattt gtttttccaa
    14401 gtcctgttca aatcttcttg acctatcaat aggtccagaa cttaaagttg gaaaaaataa
    14461 cataaaataa agcatctttg aaattttaac ttcttttata gctccatcat aaatttcaat
    14521 aaccatttgt atagttctga aatttaagta tgatattcca ataaatccaa ttattccaaa
    14581 agaagtaact ggagatattt tatttattat tattgggagc attgatgcaa acaagaatcc
    14641 ccaatatatg tatttatttt tagtttttct tcttacatat tcatatcctt taactattat
    14701 tacttcaaga ataataaata ttaccaagta ctttagttgg acatcaattc ctactattaa
    14761 gaatatcata aacaaacttg ccaacatacc ataatacttt atattcttgc ccattagacc
    14821 taaaattact gctggtattg atgttaataa taatatataa agataaaaat aatctccata
    14881 ttgtgaaaaa atcattaaat ttcctccata agtttctttc tgtctatttt accattgata
    14941 tttgttggaa actcagagat tattgaaata tttcttggaa tcatatatga aggtatatac
    15001 tttccaagtt ccttttttat tatcatccca tttttaatat tacttaaatc attcttttca
    15061 tttaactcaa caataccttt taagtaagca attttttcgt ccttatatac tggtaaaact
    15121 actgcatttt ttacattatg tacttttctc aaattatttt ctatatcttc tatttcaatt
    15181 ctaaatccat ttaatttaat ctgaaaatct tttcttccac aataatatat atttccatct
    15241 aaaagatatc ccatatctcc agttttataa gctctccact ttacaccatc tatttcatca
    15301 tagaaaaata cttcatcagt cttttcttta ttattgaagt aacctttaga aactgatggt
    15361 ccaattatta taatttcacc cttttcattt tctttaagct catttccatc ttcatcaagt
    15421 atttttattt tacaatttga catagggtat ccaactggaa gacttttttc atcatctata
    15481 gccttttgag tcatatcatt tacacttaca ccaacagtag cctcggttgg tccatatcca
    15541 ttgataattc ttgtgtttgg aaatctactc ataagttctt tagtaagatt ttttgaaagt
    15601 gcttctccta tgaatatcat tgactcaagg ttaggaagca ttttactatt aaactctttt
    15661 tcagttatac atactcctgc aaaagaagga gttgacaccc atacagctat atctgagata
    15721 ctaaattgtc taaatagttc tttatagtct gctaatacat cttttgatat tgaaaataat
    15781 gtagctccat ggataagacc agggtatatt gttgtaactg aaaggtcaaa agaatatgct
    15841 ggttggttca ttattacttt ttcacttcca tctatgttta gatatgggct tatccaatct
    15901 gaaaagctat ctaaattgtt tgaacttatt tgaacccctt ttggctttcc tgtacttcct
    15961 gaagtaaata gtatatatgc attttcatca tcttttaccc agttttcttt atctaatgat
    16021 tttccctgat attcatttat tatataattt aatttatcca tatcaattac attgatatct
    16081 ccaaaatttc tttcatcact aaagttaaat aatacctttg gttttatctc tttagtgact
    16141 tcaaaaactc tatcaattgg aaaactaata tcaagaggca catacgctct acctgatttt
    16201 aaagctccta tcatacatgc cattatcatg ttttctttat ttccataaat tactatagga
    16261 gtatcttctt ctttgtatac atcctttaga aatactgata tagcatctga atattcattt
    16321 aaatctttat aagaaagttt atctccatta cacattagtg ctgttctatc tgtatttgaa
    16381 tattttttta ttccttcaat aattttcata taagaatgct cctttaaaat ccgttataaa
    16441 taaatggcaa ttctttaaat ggagtaaatg ttagaactcc tatcgccaat attataacca
    16501 tagttaaaca aatactagtt aacaaatctt tattgttctt taaatatttt aaataatctc
    16561 tcacagacat ctacccatcc tttcgtacca agatgcatta catcccttaa ataatactta
    16621 tctgaccctt tatctttaag gtttagaact tcaaagcctt tgctttctgc tattttttgt
    16681 gctttatcgt agtactgatt tctttctttt tcagaaatac cagtcaaatt atagaattta
    16741 tccatacttg ggattaatac aacaactggc ttaataccta agtcagtaca tacatttagc
    16801 atcagtttat aattttcaaa ctccttagat gttaataaat ttacatcttt gtctcttcct
    16861 ttgtattgct ctataccatc tttaaaatgc tctttataat agtacttatc aatatttagt
    16921 ggatttttac caactctttt tttagcatct tcaatggctt tctttctctc atatgaccaa
    16981 tttattggtc tttttctttt tgttgctctc tttttatcta gcttaattaa tcgtttataa
    17041 agaataccct tttctttaag agctatacaa tactttcttc cttgaaaata aggctctaaa
    17101 agcacctttt cagctttttc aggaaatgtc ttaggctcat atagcttagc atataatgct
    17161 tctgctttat actcgtcact tccccataat aacttacttg atttttttgc atattcaatc
    17221 ttattttgtt tagatatttt tggattatct aaaaatcgat aaaattgtat tggtgaaaat
    17281 ctagactgat aatggtgact tgtgactccg tctttttcca taaaccattg catagaaatt
    17341 aacaagacaa ctttcttatt atcaatatta ggattcatac ttcctaatat tgcagcatct
    17401 tgtaatgtct gagtataggc tctcccaatt gcaaacacct tatttttact cctatttgta
    17461 ttaaaatagt actttggatg ttgttttgtt gaattactaa gttctgatga ccccaaaatc
    17521 ataatatcct tttctcttaa aaaatgatta tttgctgtaa cccctttatc ttttatatca
    17581 cttaaagtat catccataat tggaagtaga tttttctccc tcaaaagttc atcagtttta
    17641 gaatcaagaa atttgtctaa cccaaataaa aatactacgc ctattataaa aggtgtaata
    17701 aagtatatca attttctcat attttctctc ctctaaaaat attcaaattt atgttattat
    17761 taatcatatt agttttgata tgtatattca actacaaaat tgtaataaaa tcgtcaaaac
    17821 tttttttgat actgttacaa aattgtaaaa aaaaagaaaa aaacgccaaa aataaatttc
    17881 tttttagcac tttttcatac ttataatttg acattttaac acttggttaa gtatacacct
    17941 taccttaact taaaattaaa tttatttaag aatatatatt ataaattctt atattttcta
    18001 atataaacta tatactatca gctggataaa caatactact ttgtcttctt atctcatcca
    18061 taatttccat tactattatt gaattttcat gagaatttat atttgattct attttattgt
    18121 tatttataag acttataaac tctacaagtt cataatacat tccttctatt tctctaggct
    18181 tttcctctgc tttttctttt ggaatagata tatcttcttc tcttccatct ctgtatttaa
    18241 taatagcttt ttcaaataga ttaagctttt caattattat acttccctct tctccctgta
    18301 tttcagatgg tatataagaa tcagctactt tagaatactg aattatcgca tccatatcat
    18361 catattgaaa tacagctgaa ccttctccat ccactccagt ttgaagtata tgagaaactg
    18421 cctttacagt ttttggagca ccaaataaat tcaccatagg atgtatacaa tacactccta
    18481 tatccattaa agctccattt gacaactctt ttttaaaggc attttctata attccatttt
    18541 tatatttatc atatcttgaa gaatactgac aatagcttcc aaaaaatctt cttattttcc
    18601 ctattttata caagttttct ttaactgctt taaagtttgg aacacatgta attctcatag
    18661 cttccataag caatacatta ttatctttgg ctgtttttat cattgatttg acttctttta
    18721 aattagatgc taacgacttt tcacaaagca catgtttttt gtgttttaaa caagtaatgg
    18781 tttgctttga atgtaatgca tttggagaag ctatgtatac agcatctata tccttcgatt
    18841 tagccatttg ttctaaatca tcaaaaaaaa tacttgctcc atatagagtt ccaaattctc
    18901 tagctttttc taaatttcta gaatatacag caaccaattc aaagtcttta accctagatg
    18961 cagctcttag aaatatattt gctatattgc ttgtcccaac aataccaaat cttattttac
    19021 ccatcataaa tcactcccca ttttctacac tttattttaa ttttaataaa aaactttaca
    19081 acttatagat atattataaa ataattttat caaataaaaa agaaagctaa ttttaaatga
    19141 tttcaccatt ttaacatagc tttcttttaa ctacaatcta aattcaactt atatttttaa
    19201 agttatcttt ctactatatc tttatttccc ctcaaaaatt ttatagtaag aatttcatcc
    19261 acaaacaatg ttactaaaag tatagttaca acaattggcc aataaggtat tataagacta
    19321 tataaactat caactatata cacttgaaaa tatctaactc caataaatgt caatatagtc
    19381 caatatacag aaaactttag acatactatt cctctactat tgtacttata atctgaataa
    19441 tcccaataga ccttattaaa atatactttc ataagtattc ctgtaatata ttctactact
    19501 gtcggcacta ctagacataa taaaagcaat gcaaatatat tattggggtc aataaatctt
    19561 gagacctcta ttataatcga cattgcaatt gcatacattg gtttaaatgg accatttaaa
    19621 aatccatctt cttgaaaatg cccttgttta taataactat ataagttttc aattatccaa
    19681 cctataaaac catacaagaa aaaattaaat aaaaaatata atagagaacc tacattatcc
    19741 atgaatattc ctcctagctg tttatactta ttttttctca tattcatgga tttattctaa
    19801 atcaaagaaa ttatatttaa tttatttaat taatacttta tattatagat tgtgacattc
    19861 tttagagttc aaacttttta ggtattctct aacttccagt aaattttcaa gtatcttatg
    19921 tgattgtgat ttaatttgct catctggctc ttttaaatct ggtacattta tacatcttat
    19981 accaccattg tatgcagctt caactcccat aggcgaatcc tctatgacaa tacaattttt
    20041 gggattaaca tttatctttt tagctgcttt taggaatatc tcagggtttg gtttcgagtt
    20101 tacaacatca tctccacaaa ctatagcatc aaagtaatct tttaaatttg ccttagctaa
    20161 tctctttact gctctttctc tctttgttga tgttgcaaca gccattttgt atccattttc
    20221 ctttaaaaaa gagattagtt cattgactcc taatttgata ggagctccct tcctctccat
    20281 aaattcaatc atatttttag ttttttcgtc atataaatct attattggta cagaactatc
    20341 gtatatatct gtaagacctt ctattattcc tttacgattt cttcccataa ctgatgtata
    20401 aatttcctta gtcatagtat atccatactt ttcaaacgtc tccatccaaa attcaagaga
    20461 aattctctct gagtcaaaca aaactccatc catgtcaaaa ataattcctt ctactttttg
    20521 catacaattc ctccaatatt ttttgatata attatattac actttttatg attaatttta
    20581 caaccctcaa tttatccaat tctaatattg taaaattgta attttcaaaa gttacacttt
    20641 ggtttacttt aatatttgaa ccaagcatat aggatatcca tccacctata ctgtcaaatc
    20701 catcatgctc tatatcaagt ccaaaatact tattaatata gttgatagat tcagttccat
    20761 caactaagta agaacctgct cctattttct taatatgagt ctcttcttta tcaaattcat
    20821 cttgaatttc tccaactatc tcttctagta tatcttctat tgttaccaca ccagatgtac
    20881 caccatattc atccacaact atagcaagtt gaagtttttc ctttcttatt ctctcaagag
    20941 ctttatctat agttaaattt tcagatatat atataatatc tctcaatatt tcttctagtt
    21001 caattttatt ttcatttatc ttttgattgt ataaatctct tatatgtaca aaacctaata
    21061 tatcatcttt attttttctg catactggat atcttgtaac accttcctct tttaaaatag
    21121 ctaatatctt ttcttcagaa tcactttcat atatacatac catatcagtt ctaggaacca
    21181 ttatctctct aattttcttt tcttcaaatt caaaaatatt atcaactaat ctttgctctg
    21241 attcatctat aagtccactt ttataacttt cttctactaa tagtcttatt tcgtcacctg
    21301 tatggggttc atcaacctca tcagcttgtg aatatccaaa tggtttaaga aataaatcag
    21361 tacttaagtt gaaaaaatat attattggat atgttaactt ataaaatcct actaataaaa
    21421 aagatgtact caacattatt ttttctgtat tataaagtgc taaagcttta ggaaccaact
    21481 ctcctattac aacctccatc attgttataa ttaaaaaaga aatggaaatt gatatagtat
    21541 atataatact ttcactaaga ttaaatacac ttactattgg taaaattaac tctttaactg
    21601 tagattctcc catccaacct aatgcaagtg aacaaagtgt tataccaagt tgacatgcag
    21661 aaagatagga atttaagttg tcttttatta ttttacatct ttttgcatta ttattacctt
    21721 cagttatcat ggtatcaatc ctagaactac gaagttttac catagcaaat tcacaagcta
    21781 caaaaaaagc atttatcaaa acaagcatta ctataagtgt tacttttaat aactcccgca
    21841 taaagtatag gttcttataa tgtaagaaat ctataagaac tcaaagttcc ccccttatat
    21901 taataaattt aatttataat atatattcta tcatatttat taatatatcc tactttatta
    21961 caaataattt ttataaacta aataacccct tttaatattt atgactggct atttgataaa
    22021 tattaaaggg gttatttagt tatcattttt tatttctaaa aatcttttct caaatgattt
    22081 agttatctat ttatccaatt ctttacataa tttaatgatt aaaaatatta attttttcac
    22141 tataaagtat aaatattatc tgattattaa aataaatatt aatactataa ataaaaacga
    22201 agcatgattt ttatttaaat aaatctcaaa cttcgtcttt acttacttag atatttattt
    22261 actttctaaa tcctattatt tttaaaacct tatcttttta atacttcacc acatttattc
    22321 tcagtaatct ctccattttc caacgcaatt tttccattta caattacata ttcaacacca
    22381 ttggctagta attgtggctt tgaaaaatca atatcttctg acctagaata actatagtta
    22441 tccatgtcaa taactgctat atcagctatc aacccttctt taagaatacc tctatttttt
    22501 attttaaatt gcctagctgg taatgaagta actcttctta caatctcttc caatctaaca
    22561 ccagactttc tgtacatatt gaagaaaatt ggaaaagctc ctcttctttg tagttcaaac
    22621 catgacatat ccccacccac actaaacaaa caatctgaac caaccataac aaatggatta
    22681 tcaattattt tatcatcatg tagtttatct gggaaatcag ctctatacat tcctcctaaa
    22741 caaaagataa gttcttcgtc tccatctaaa agtaaatcga gtaataactt gtcttcatct
    22801 attccttttt gtgtagctat ttcacgtatt gatttctttt ccatattaat atctttagtg
    22861 tttagaagta ttatactccc cctatctcca agtataaatg cttcttttaa tataagtgtt
    22921 cttccctctt catttctaag agcatccatt accccattta tacctaattc aaatagacta
    22981 gatgatattg ccataataaa ttgaattact ctttttttct tcatacaatg cccagaactt
    23041 cttggtactg tgtcaaccat tatttcaaca ccattatacc tagcctttaa tatctcatca
    23101 aatgcttcta tttcaactgg acttaagtga gatacttgaa ccctagcacc acttttttgc
    23161 ccaacctcta tggcttcttt tactgcatta tatcttccta tgtaatctct aatatgagat
    23221 gtatatatac catcatgctc tttaatctgc tttgcaatat caacaagttc atcaatatca
    23281 gcatacttac ttggtatata tgccaatcca gtagatattc caaaagcacc acttttcatt
    23341 ccatcattta ttatatctgt aatttcattt ttttcctttt ctgtaggagg tctatcctta
    23401 gaacctccca taacactcca tcttatagtc ccatgcccca acaagaatcc catattgaca
    23461 gaaataccac ttttagatat aaggtcacaa tattctgtaa aattattcca acatttattt
    23521 ttatctataa gatacttttt ttcttcttca agtaatagac catttttata catatattca
    23581 tatacatttt cagaagaata tggtgttata gaatgtccac aattaccatt tatagttgtt
    23641 gtaactcctt gttttagaaa cttttcaaat ttaccatcta gtattgctac tatttcttca
    23701 tgaacatgag ggtcaataaa tccaggtgtt ataacttttc cacaacaatc aatctcttta
    23761 tttgtattgc tatttatctt agaatctatt tttgctatta agttgtcttt aattgctata
    23821 tctccataaa aaccaggatt acctgtacca cctattataa atccattttt taagattaaa
    23881 tcatatatca aaatattccc tccttaaaaa ccaattttta aataatctta atgtaatttt
    23941 tatatttgaa aatcaaatta ttatatttca tatttgaaaa ttcactatta tttcattgta
    24001 attagtcact aagcttatct ttatacatag ctcttgcaat taacatagta ccaaatacac
    24061 atataagaac tactagagac tgtggtatta taccttgctt tgataatata atagtcaata
    24121 cagatattac aattgctact aggcctaatt ttttatcttg taaaaatact tgtccaaaaa
    24181 ctgacccaaa tagagctggt aaaattaagt ttaatttttc tactacttca gctggaattt
    24241 tagatagtac gcttcctcct aaaattaccc ctatagttag tatacttata ttcactaaaa
    24301 tagatacagc tattcctatt gtagatatta tcgagccttc ttctgtacct gattcaactt
    24361 ctgctgcctt ttgagctgct attgaacatg gtagcctcat attagatata ttaccagaaa
    24421 gaaaactcat ataagttcct gggataccta agattggtga ataagaaact ggttctatta
    24481 tgtaatttgg agcactcata ctgacaattg ccattgtact tgctaataat gctgatattg
    24541 gaggcataat accaaatcca aagctcaaaa ttattccagg aactaatgct gctataatcc
    24601 ccaaagatag tgttagtctt ccatacctta tcttaaaagg taaatattct tcattgtata
    24661 tagattttac tttactcata aaactccccc cttatattac tgaagctatt atcattccgc
    24721 taaacattga tattgtaagc ccccactctc ttaaccattt tatatttttc ttcttttcaa
    24781 gcatacacaa tattaccatt atagccattc cacttataca tgcaattgtt ccattatcaa
    24841 aacgcaacac cctatcagca tttagatatg caaatgaacc caacattgct cctagagata
    24901 ttattggtat aaatgatttc ttgccactag atataacatt ggttatctta tctagtttat
    24961 gtccaaatag taatgtgaat attatccatc ctaaagaacc taatatcata gtccaaactg
    25021 catttgtaaa tgcaagtttt gtcatttcag gagaacctaa agttatacct aatgcatctg
    25081 ttccaaatcc ggctgacatt gattcaaaaa ttacagaacc tataaatgat aatctcatcc
    25141 atgctatagg cccacccata gttactataa gcgataccat tccagcaaat atagtcattg
    25201 aaggcccaat agctgaaata gcactactct taacagctga ctttatttgt ttatctgtta
    25261 ttcccattgt tttaccaact ttgcaagatt ttatagcaaa tataagggat tgtaccacta
    25321 ctattgatac tgctactgta ctcgctatcc acaaaagtgg atgattagct aattttaaat
    25381 aatccattta taaaacctcc ctataaatcc tcaaatttta ttaatatttc taatatatct
    25441 atttccaaac ctgttttagt actctaagta tatttccacc tagtaccttc tctatttcct
    25501 catcactata tccatgcttt actaaatatc taacaatgtt ttttgaagtt tctgttgggt
    25561 tctcaagacc ttttacatat tctactttgg gatgttcttt tgttcctgtt atttttttta
    25621 tatcaaattt agcagctagt actgagtgta attttacatg gtcgccatat actgtatctg
    25681 gtccaaaagc tacatggtct attcctacta aatttttaat atactcaaaa tgttccataa
    25741 atgactctat tgaatgttct ttattcttct ctgttattgt agtatgaggt gctgcttcta
    25801 cacctataac ccctcctttt ttagcacatg ctattaatac ttcatctgga gttagtctct
    25861 ttgtgttcca taaacttctt gccccaacat ggcttaatat tattgggtcc ttgctatatt
    25921 ctattacatc aagtgtagtt tgaactccaa cgtgagagca atctattgcc attccaattt
    25981 tattcattct ttcaacagct ttttttccga aatttgtaag acctccatct ttctcttctt
    26041 ttagtcctga acctaatgca ttggattcgc tatatgttat acccattaac cttataccaa
    26101 atccatacag tatatctatt ctatcaagtt cattttctat tggtgctgca ccttctaatg
    26161 ttggtatcaa tgctacttta ccttcacttt tagctctgta tatatcttct actttttcgc
    26221 actttataac aaaatcttga tgagctaaat cacatagtct catgcctaaa tctattaata
    26281 tatcatccca tttccaccct gaatttgatg ttatcgtaca tacaccatcc attaaattat
    26341 caaatatagc atcataatat cctcttgata atgcttcata agcacatctt tgtttacctt
    26401 ccctattata ttcaaatata tctctttcta ggtgttctgg aaataatact ggatgttcat
    26461 gtaatgatat aaatattttt tcatccacta tacttttaac cttagcttct tgaatatcat
    26521 ctaattcaat aaggtattct ttaactcttt tatctccttt acacatctca atagatgaaa
    26581 tatcttttcc tttttctaaa taactatagg cttcatatcc tttgtaagct gacttcataa
    26641 caacatcctc caagttctac aattttttat atttttccta tgtagcaatt gatgtgccaa
    26701 aatataaatt ttaattgtat aataaatctt gcaaaaaata aaaacagtag taaggttgat
    26761 atttactact gttttattaa aaataatctt cttagattat ttattcaata tttttgaatt
    26821 atcttaatct taaagataat tttatttatt tctatccatt atagggattt ttttagggtg
    26881 ttttgccttt ttagtcccct atatcactcc cttaattttt acatatgata taaagttctt
    26941 tccttcatca gttataaaac taccttgttt ttttactcca gataaaagta aaccatggct
    27001 ctttaactta tctattcttt ttctaatttg gtctacactt aaaactatat ctttttcttt
    27061 taaaatctct tgcagtttat ttcttcctaa taatatattt ttattattcc aagtttctat
    27121 actggtcaat atacatatac tttcctcaaa gaaattagat tgtttgaaat ctaagataat
    27181 tgaatcgaaa ttttcattaa ctaaagtatt gtttttttca aatctaaatt gttctggcaa
    27241 atgctcgtaa tctactctat cttcctcaac tatagtatca atataataaa ttaaattttt
    27301 aagctctctt acatttcctg gccattcata caatgttaaa gcttgcattg attcctctgt
    27361 aaaacatttg ttgctattta tttcatctaa aaaatactta cttataagag gtatatcttc
    27421 cttacgttct ctaagtctag gtatctctat atgtaataca ttaatcctat aatacaaatc
    27481 ttctctaaaa gaaccttctt taattttttt ctttaaatct ttatttgttg cagctataat
    27541 tctaacatct attggtataa ttttacttcc gcccattctc ataacttctt tttcctgtaa
    27601 tactcttagc aatctctgct gtacatctaa agatatatca cctatctcat ctaaaaaaat
    27661 tgttcctgta tgtgctcttt caaatatacc catttttcca ccttttattg ctcctgtaaa
    27721 acttccttca tcatagccaa aaagttcact ttcaataagt gtatctgaca aagaagatag
    27781 attaactgca acaaatggct tgttttttct tagagattca ttatgtattg cctgggcaaa
    27841 tatttctttt cctgttccat tttctccaag tatcaacaca gaaaagtctg tagttgctat
    27901 ttttcttgca atattaattt tttcttttat tattttactc tcacctacaa cactctcaaa
    27961 tgtatacttt gatacaaaac cttttgactg aagtttattt tgaatcttgt cctcaagcac
    28021 ttgaattgca cttatatttt taatgcttat aatactcttt attcgttcat tattttcata
    28081 aacatttact ttattaatta tcagtttttt gttatttaaa tttactactt catcattaac
    28141 ttcatcttct tgaaaaaata tttttttgac aaccttatca ctaaataagt ccataaagtt
    28201 attagatata atttcatttt ggtctattcc aactagatta gaaaatactt tgttgcaata
    28261 tataaatttt cctaatttat caacagaagc aataccttca tctataatct ccaaaaaact
    28321 cttcatggtt ttattcatag ttgtataata cctatatcca cttactgtat cttcattgta
    28381 tttttcctta ataatatgta gtttatctat agatatattt agttttgtaa agatttctat
    28441 aactgtattt atatcaatta ccttatcacc tatgtcaatt atttgcttta tgttttgtgg
    28501 tatgctgttt ctgcttcccg taataattcc aatctcacat ttagatttat cacaacctgg
    28561 ataatatggt attagattaa tatgaattaa tcctagtttt ctaattatct tggcagtttc
    28621 atctgctgat tctttataag catctataac cataacatca gaatcatttt ctatacttat
    28681 tatctgattt atattttcaa tatttatagt acgatgtact attacaatag gtatattttt
    28741 atcaatatta ttatgtatat attcctttat atcattgtct gaacatacta caagctcata
    28801 gcttgacagt tcaatattta tcctatttac atataccaag ttatctatat tacaaaattc
    28861 tccaaatata ttttccaatt gttttgatat atctatattt attttgtcat cagttgatac
    28921 aaataaaata ttatgttttt tcatagtccc acctcctgtt taacgagtat agaaagtaat
    28981 aatttggtct attgtagcac tttttaaaaa agttttaaat cttaaaaatc aaattttgta
    29041 ccatttacta ttattttcca taataaaata atgtaagcta tcttttttca catataattt
    29101 aatttctaaa acggttagtt tgacattatt ggaatataaa caaaaattta atataaattc
    29161 gttaatatat taatacattt ttaagaatga caaggaataa attataacaa attttaggaa
    29221 tatataataa tagggtctca gaacttagtt acaagttcta aaaccctatt tgtttagtgt
    29281 aaaaaacatc ataaaattta gcttaaatct tttcacataa tattactctt tttctaagtg
    29341 ataataaaat ttatctattc ctctaaaaac tgtaaaaatt tctgattaaa tagtttaagc
    29401 tcatcataga atatagcatg accactatac tcaaaagtat ataaaattga atcttctatt
    29461 ttttcattca taaaaactgc aaattcatac ggacatattt catctaattt cccatgaaat
    29521 ataccagtag gcactcttac acattttaaa tcattaaata attcttcatc tcttaaagat
    29581 acagcagttc caatagtgcc aatacctgat gcactaaaac caatatcatt aaaccatctt
    29641 ctaaagcttt ctggtggatt tgatgcaaat actttttcgc caaaatcggt taccatttct
    29701 ggtctatcag tacatgcttg tgctatcaat ttatttacat cttcacgtgt cataccatat
    29761 ggaaattctg gaggtctttg tacaaatgat ggtgcagcag ctgcagctaa taccaatttt
    29821 gacactccat atccattaaa taaactcata tacctaagta cgattgctcc tcccattgaa
    29881 aaaccaacaa gggtaaagtc ttttaatcca atagcatgta ccaccttata aatatcgtct
    29941 gctaattggc tataagtata tcctcctgat gttgcatcag atttaccaaa acctcttaaa
    30001 tcaattgaaa ctgttctata tccgagtttt ggcaatatat ttgtttgata ttcaaatatc
    30061 ttatgtccta agggccaacc atgtataaaa agtacagttt ttttagcact cggattcaaa
    30121 tcatatactg ctatgtttat atcattcaca tatacataat acatatcaac agcaactccc
    30181 ttcaagaaaa tgtatgatgg ttattttata tatatgaata aaatgatgaa taactaaatt
    30241 ttcaaattta tttacaatac ttctctattg ccttttcaaa taaacttaca tgaagttttt
    30301 catctaggat tattctattt aatatagctt ttatataagg gtcttcaata agacttatat
    30361 ctttataata attattaata gccacatgct ccaaatgcaa atctagtttt aatctgttac
    30421 aaatagaatt tccataacat acaaaaccac cattccaata tgcaccacaa gaacttgtag
    30481 aacctctata tacaggattt ccacccaata atcttatagt ctttgctaat atctccatat
    30541 gtaacatttc tgttatagat atatttatcc acatttcact taactctcta tgcgtttcat
    30601 ctaaatcaaa attatggtat agatattgat ttacactcgt aaattcactt gatactccgg
    30661 catagtcatc catcaataat tctgcataat acttatttgg acctaaaact tttatctctg
    30721 gatatggctc atcacttgaa tatccatttc gcttgtgcat gtcataatgt gcatcactca
    30781 taatatctcc tcctttaaat ttaatacatg atattaattg tatgcatcac gactttttca
    30841 tataacttag ataataaaat ctacttaaat aataaaaagc catattaatt aaaattaaca
    30901 tgacctttta tccacaaaat tactttttaa ttattcatct tttccagcta ctgatagctc
    30961 tttaataaca actgaaggtg aacctatact actcattgga aattctaaat cttcccctat
    31021 agcttcaata tctttcaaca ggtcaaaata gtttcctgct actgtaattt gctctactgg
    31081 aaatactttt tttccttctt tgatataaaa gcctttggca gctaaagaaa agtctcctgt
    31141 tactgaattt gcacctgaat gaagtcctgc aaagctagta accatcaatc cttcatctat
    31201 atcctttata atttcatcta aagatttatc tcctttctct atataaaaat tagttggata
    31261 tatgcttata ggtgatgaat atgaagattt tattccattt cctgtagtct ttacacctgc
    31321 cttattagcc gtttttaagt tatgaagtaa agttataagc tttccattta aaacaacttc
    31381 ttttttaaat gtagctactc cttcatcatc aaaaggagta gatgccatac cattttctaa
    31441 aagtgggtca tcaactattg taactatagg agatgctatc atgtctcctt ctctattttt
    31501 caataaagat aatccttttt gagctgaatc tgcattaaat atcccagaaa atgtgctaag
    31561 caaagatacc atagcttcat taagcaatat agttttatat ttacctgatg gaatactctt
    31621 accacctact ttagataaag cattatcaac accaagtttt gctatctcac aaggttttat
    31681 ttcttcaata gaatttgcta tattatatcc tattccatca tatttttgtc cattgtcttc
    31741 tatgatagga actacaaacc ctataagcat attagtttta ttgcttaaat taagaccttt
    31801 agtattagat ataccattac ttgatacaga ataagatata gtacatttag ataaatttac
    31861 caccttatct gaataagctt tagtctctct ttccatttct aaagctaaat caatcaactt
    31921 atctgcctct aaattttcta gctctttaga ataagtcttt acatcattat agtgcttatc
    31981 tccttcatat ataaattgta catcttcatt ttcaatagtg tttactccat cttttacatt
    32041 ttttatcaac atatcaacag ctttatcatc taaaatttct gtataagaat aacctatctt
    32101 tccatttacc ttacctctaa aagataaacc aaaagattta tcaagattgt atttctcaac
    32161 ttctccttca tatatattta tacttaaatt ttctcctgta taataatata tttcatactc
    32221 ttcaaaacct tcacttagag cctttttaaa taatatatct ttaaaatttt taagttccac
    32281 aattatccct cctatcttcc acctacagta atttctttta cccttatcat aggttggcct
    32341 acattagttg gtatacttcc tgatgatgag ccacacatcc cctgagcttg ttttacgtta
    32401 ttcccaacca tatctatatt cataagtata tcgctacctt ttccaattaa actagcacct
    32461 ctaactggct cttgtatttc tccatttttt attaagtaac cttctgaaac tgcaaaatta
    32521 aactctcctg ttacaggatt tacagaacca ccacccattt ttttagcata aagtccatct
    32581 ggtattgact ttataatatc ttctggtcta tcttctccag cagcaatata agtgttagtc
    32641 atccttgaag ttggtgcaaa tttgtagttc tgtctacgag aacttcctgt aggattcatt
    32701 cccattcgtc taccattaag tttatctatc atataagact tcaaaattcc attttcaatc
    32761 agtatattct tttgagttgg atttccttca tcatctatat tcatagaacc ccagtagttt
    32821 ggtattgtac catcatctat agctgtaatc tttgtggaag caatctgttg acctaattta
    32881 tctgcaaata cagagttccc ctttgcaact gatgtagctt ccaaagaatg tccacaagct
    32941 tcatgaaata ttactccacc aaatccatta tctattgcta ccatcatatt acctgcagga
    33001 caatttttag catgcaacat agtatgcgct actctagctg attcttttgc ataatattct
    33061 gggtctattt cttcaaatat ttcaaaccct ttacaacccc caggaccttc aaatccagtt
    33121 tgattttcat tacccttaga tgcaattgaa cttatcccta gtctggttct tattcttcta
    33181 tcctcaacat atataccttc agtgtttgca attaatattt tttggtcttt atccaaatag
    33241 ctaacactta cttgagatat atcattacta aattcttttg cactcttata tgcaaccttc
    33301 ataacactta ctttatcttt atttcctatt gaatttggat aaatttttat attatgtatg
    33361 ttatttattt taatactgtc atttaatatt acactttttc catcttccaa tttacctaaa
    33421 gcaacagcag ctttgtatgc tacatccaac agactattta atgaattgtc acttgtataa
    33481 gcatatatac ttttcaatcc tttaaatatt cttattccta taccataatt tcttccacct
    33541 attgcatttt ctactttatt atctattaaa ctaatagaat tatttatagt gtcttcttca
    33601 aaaatctcag caaaatctcc tccagtaatt agacattttt ctaatacctt agaagctata
    33661 ttttttgaaa gcataaattt acctcctact ttaaattttt aattaacttt tattcaatct
    33721 ttttacttgt taacaaacat tatatactat attacttaaa ataaggtaat tatgaatata
    33781 ttatacatat gttttatact aaaatgttat cacattttat ctatacatac ccatataact
    33841 agataattaa aatgtataat attatttgct atagaaaata atacactcat acataataaa
    33901 ttttaggagt gaagtatatg aatcaagaat atgtaaaagg aaatcctatt tttaccaata
    33961 ttaataaagt tccaagacaa tttccatacc ttactgatga tattgatact gatgttataa
    34021 ttgttggtgg tggcgtaact ggatgtattt gtgcctacta tctagctaaa aacaatataa
    34081 agtctgtcat tcttgaaaaa ggaaggattg cacatggaag cactagcgtg acaacttctc
    34141 tattacagta tgaattagat gacaatttga tagatttaac agaggttatg actctaaaag
    34201 atgctctaaa agcatataac ctttgtactt cagcacttga agaattagat acatttatag
    34261 agctatatgg aaataagtgt gattatgcca aaagagatac tctactttat actgccaaca
    34321 aacttgaagt taaggctatc aaagaagaat ataacttaag aaaagaaaat ggatttgatg
    34381 ttgaatatat tgatgaatcc acaaaccctt ttaactttga tttaaaatca ggattgatag
    34441 caaagaatgg aggacgagaa ttagacccat ataaatatag tcaccatttg attgatgtaa
    34501 gtttaaaaaa tggtcttcaa gtatatgaaa atacagaagt aaaaaaagta gatttatcaa
    34561 atgataaggt tactgctgaa gtatcgtatg gatacaaagt tcatggtaaa aaattaattg
    34621 tagctacagg gtacaataca agtttattta caaaaagaaa ttttgcaact aagtcaaata
    34681 cttttaatat agcaacgaaa ccacttaaaa acatagcttc ttggaaaaac aacattttaa
    34741 ttagagataa ctgtgaccca tataattatc taagaactac taaagacaat cgattaatta
    34801 taggtggtga agatgtaagt tttgatgata tagaaaatga aactttagcc aatgaaaagt
    34861 atgatatttt agaacaaaga ttgaaaagta tgtttaagga tataaaagac attgaagttg
    34921 aatataaata ttgtggttgt tttgcttcaa ctttagataa tttaggtttt attggtccag
    34981 ataataaaaa taacaatcta tggtattgct taggttatgg agcaaatggt atactctttg
    35041 caatattagg aggtataatg ttaagtgaat tatatcttgg caaacaaaat aaaaatatga
    35101 aattatttaa agtagataga tttgataaat agatattata tattaaaaga ctgtaaaaag
    35161 atgaaacttt ataattctaa aagttaactt tgatacagtc ttttataatg ttccttttaa
    35221 aaatacttta tttataatta aatataaagt aaaatgttaa aatataactg ataaaattta
    35281 gtcataagat aatatttaag tttatttgat gaaatatgga ggaattatta tgaaggaaat
    35341 actcgttatt gctcccacta aaggaaccta tgaaaaatca attcacatag ttaaaaaaaa
    35401 caaatataca aatattgatg ttgtatttgg caatctaaaa gaaggtatac ctcttgctga
    35461 aaaaagtatt aatcatggta ctagaattat cataagccga ggtggaactt acaatatgtt
    35521 aaaagctact tacaatatac ctatagttga aattaaggta gatgcttatg atattataaa
    35581 aagttacaaa gaggtaaaaa attccaacga accatttgga ataattggat ttaataatgt
    35641 catctacggt ttcgatatta tagaagaaat attgaataag aaaataacta tgattgaaat
    35701 tgaaaaagaa gaagaaattt atgatgctat agaaaagtac agaaagaaag gtataaacac
    35761 atatatagga gataccactg ttgcacatat tgttaagaga cttaattgta agggaatatt
    35821 aatcgaatct agagaagaaa acatacttag agccattcaa caagcagaac aaatactcga
    35881 agcaaccaag gatgaacaaa aaagaagatt acagatagaa gctatgacag attttgtaca
    35941 tgatggaata ataacagttg ataaaaattt taaaataaca ttatttaata agagtgctga
    36001 aaaaatattt ggtataaaaa aagaaaatgc actttatcat aatgttgtag atgttatccc
    36061 aaacacagtt cttccacaag tagttgagac tatggaacct caaattggtg aaatacaaaa
    36121 tatagggagt acaaaaatta ttacaaatag agttccaatc attgttgatg gtcagattca
    36181 aggggctgtt tcaacatttc aagatagcaa ggagataagt tcttttgaac atacaataag
    36241 aaggagctta ttaagcaaag gtctatctgc taaatacact tttgatgata taattcatgc
    36301 tagtgaaaag acaaaagatt gtatagaact tgcaaaaaaa tatgcttgtt atgatactcc
    36361 tatgattatt actggagaat ctggagttgg taaagaacta ttttgtcaaa gtatacataa
    36421 ctatagtaag cgtaaaaatg caccttttgt tgctgtaaat tgtgctgcca tacctccatc
    36481 tctaatagag agtgagtttt ttggttatga ggaaggttca tttacaggtg ctagaaaaaa
    36541 aggtaaagca ggtgtattcg aactagcaca tgaaggtaca atcttcctag atgaaataag
    36601 tgaaatccct cttgaacttc aaggtcgatt attgagggta ttgcaggaaa aacaagttat
    36661 gagaattggt ggtgataaag ttattcctat agatgtaaaa attatctgtg cttcaaataa
    36721 agacttaaaa aatatgatgc gcaatggttt atttagacaa gacctttatt ttagaataaa
    36781 tatactaaca ttatatcttc cttcattaaa agaaagaaaa gaagatatta taaaattatc
    36841 agaatttttt atacataaat attcaagcaa atacaataaa acgcctttaa ttatcactcc
    36901 aaatattaaa aaggcacttc ttgaacgaga atatgaaggt aatataaggg aattggaagg
    36961 tatgatggaa agggctgtta ttgtggaatc atttgactcg attttattag aaaaggttag
    37021 caatgaatat acaaataata tagttgataa agataatagt gattttgaat gcagtaattt
    37081 agatttaaaa actttagaaa aaaaatatat ctataaaatt tataacgaaa ataatagaaa
    37141 tactacaaaa acctgtgaaa ttctaaagat aactcgctcc actctatggc gtaagttaaa
    37201 agaaatagaa gatgatgttt aaaaataata catacctata tatatcaaaa cgttttatgt
    37261 ttaattttaa tacataagac gtttatttgt tttcaataaa aaatacaatt atatgataaa
    37321 aagaatcttt gtaagtgaaa ttctcgtcaa tcgtactttt aattataagt aatctacagc
    37381 atttcaatcg attattaaaa ataatcatga taactaaaga tacaaactct atatattggc
    37441 atattaattg cttttataat acctatataa aaatgaaagg gagtgatact agatgcacat
    37501 cttaaaatca gtgaaaaaga taccaggagg acttatggtc tgtcccttgt tattgggagc
    37561 actatttaat acagtatgtc cacaagctct tgaaattgga ggattcacaa catccttatt
    37621 taaaactggt gcaatgagta tacttgctct attttgtcta tgcaatggag ctcaaatcaa
    37681 tatcagacaa gctggtaaac cattgactaa aggtatagta cttacagcaa caaaatttat
    37741 aattggtgca gtattaggta ttattgttag taaatttatt ggacctaaag gtataattgg
    37801 tattacacct cttgccatag ttgctaccat gactaattca aatggaggtc tatttgctgc
    37861 tcttgcaggt gaatatggag actccacaga tgttggagca atatctatct tatctctaaa
    37921 tgatggtcct ttttttacaa tgcttgcttt tggagtaact ggacttgcaa atgtacctat
    37981 aatagcacta tttgcagcac ttataccaat actacttgga tttatacttg gtaaccttga
    38041 tgaagatata cgagaatttc ttgcacctgg tacaacatta ttaattcctt tcttcgcttt
    38101 tcctttagga gcagcattaa actttaatca aattataact gctggactac ctggagttgt
    38161 acttggttta ggagttacta taataacagg tatgggtggg tactttgtaa tgaaacttat
    38221 acgtgcagaa catccagcag taggtgcagc tacaggtaca acagccggaa atgcagctgg
    38281 tactcctgaa gctttagcag ctatagaccc tactctagct acaatagcag ctgtttcaac
    38341 agtacaggtt gctgctgcta ttattgttac agcaatatgt tgtccaatgt tagtttccta
    38401 tctagataaa agagaaaaaa agaaaaaatc tatttttaaa acaaataaaa atattgaagt
    38461 aaattaatac ttaaggaggt aaaattaatg aatgcaatta ttcatgcaaa tgaaaaagat
    38521 aatctagtta catgtgtcag acctttagtt aaaggtgaaa aagtttcaat tgatggaaaa
    38581 tcttacatag taaatgataa tataccagtc tttcataaga tggctacaga agatgtaaaa
    38641 aaaggtgatg ttgtatacaa atacggtgaa attataggaa ttgcaacagt tgacataaaa
    38701 actggtgact atgttcatgt acataacatt gaaagtacac gtggtcgtgg agataaaaaa
    38761 taggaggaag ttaaaatgaa attaatgggt tatttaagag aaaatggtca gtttggtatt
    38821 cgtaatcatg ttttaattat tccaacatct gtatgttcaa gtgagacagc tacaagaata
    38881 gcatcacttg tgcctggagc aatagcaatc cctcatcaac atggatgttg tcaaattggt
    38941 tctgatatag agcttacagc aaagacatta ataggatttg gaaaaaatcc taatgttgcc
    39001 gcagttttag tagttggtct tggatgtgat ggtattcaag caaaagaatt agcatctgaa
    39061 atagctacaa caggaaaaaa ggtagattac gttgttatac aggaatgtgg cggaacatta
    39121 aaaacagttt ctaagggagc tgaaatagta agtaaaatgg ctcgtgaagt atcaaaagaa
    39181 gtaagagttg aatttggtat gagtgaaatt acattagcac ttgaatgtgg tggttctgac
    39241 ccaacaagtg gaatagcttc aaacccttca ataggcgttg catcaaacct tcttgtagat
    39301 gaaggtggaa gtagcatact aagtgaaact acagaagtaa ttggtgcaga acatttgttg
    39361 gctacccgtt ttgaagatga agaaatgaaa gataagtttc ttaaatttgt aagtgatgta
    39421 gaaaaaagag caattgctat gggagaagat ttacgtagtg gtcaacctac tccaggcaat
    39481 aaaactggtg gactttcaac aattgaagaa aagtcacttg ggtgtatgta taaggcaggc
    39541 aataagccat tcaaaggtgc tcttgaatat gctgatattg tacctcctga taaaaaagga
    39601 ttatatttta tggatactcc aggtcaagat atagattcta tcactggtat ggtagcaggt
    39661 ggtgcacaaa ttgtaatctt ttcaactggt agaggtactc caacaggaag ccctatttca
    39721 ccagttatta aaatcactgg gaatagtgat acatacaaca aaatgccaga caatatcgat
    39781 ataaatgcag gtagaattat aacagatggt gctaaaatag cagatatagg tcaagaaata
    39841 tttaatgaaa taatagaagt ctgtaatggt aaacatacca aagctgaaag tcttggtcat
    39901 agagaatttg gcatttacag aatttcatct acattttaga ttgtaacaaa atatctttta
    39961 taaatataat acttatgtag atacataagc taaaagttct ttctaatact ataaaaattt
    40021 tctatactga aaaggaactg tatcaaaatt attttgaaaa cagttctttt tttaacctct
    40081 tttactcaaa atattataaa ataagattta aacaataaac gtatcttgat taatctctaa
    40141 gaagacataa ataaagctaa atgtaaagtg ggataaataa aatttaatat ctttgtatga
    40201 aaagatattt ggtataatat gtctgagaga attcttattt gtaaacaaat aaaggatgga
    40261 ggatgaaaca aaagaatgaa ctttgaaaac acaaaaaata aaaaaataat agctacttta
    40321 ctattgacac ttcttttaat cgtgtcatta acatgtgtca cttttattat gaatctaaat
    40381 aaagtaacac ataatgaaac agaacgatat cttgtagaag tttcacaagg tatttccact
    40441 acaattaatg tgaaatgtaa aagtatattt aggacactat attctatggg agatacttat
    40501 tttgagatta atgatagtga aaaagaagtc aatagatact tatcaaaaaa attaaaatta
    40561 tttgaatttg attggttagg tattatagat tctaatggaa attttgtaag tgcccttaaa
    40621 gatacaggta atgttaaagg acaagacttt tatagaaaag cccttcaagg caaagaaaca
    40681 attactcctg ttaaatcaca atctggtaca tatggaattt tatattctgt accactatac
    40741 aatggcgata aaattgttgg agctgttgct gcttggaata ctattgatac tatgagaaat
    40801 ttattaagtg tagaaagctt tcatggtgaa ggattttccc aaattatcga ccaagatgga
    40861 aattttattg taagttcagc aaacaaaaat gctccaaaaa atgtggtaaa tttttttgac
    40921 atgattaaac accaaggaaa acaggttgat aaaaataaac ttgaagaaat gaaaataaac
    40981 ttaaaaaaga acaaaactgg ttctatgtat tatacattaa atgatggtat ttctaaggca
    41041 atgcactatc ttccattaca agaagaaaac ttatacctcc tttcaattgt tccaacaaaa
    41101 acagcaagtg cacagtttga tttacttcta aaaaaagcaa tcttcatcaa tattttaatt
    41161 gttatactat ttttattgct tattatattg attatgttta taaatcaaaa aaacagggca
    41221 caacttataa aaatcgccta tgtagactct gtaactaaag gttacagtaa agcacgtttt
    41281 gatattgaag ctaaaaaaat tatacagtca tcttcatcag aaagctattc attggtatct
    41341 ataaatattc agaaattcaa acttattaat gattcttttg gtagtgaagc aggagataaa
    41401 acattaaagt acatacatga tgtcattagt aattatctag aaccaggaga attgctttgt
    41461 cgagtttcta atgaccagtt taatgtactt attaaaacta ttcctcaaaa agaaattctt
    41521 aagtacatag aaaatatcac caatgatatt aatagtttca ataaaaatga agaatgtaaa
    41581 tattttatag ctctatctat aggtgtatat aaaattgatg acccaaatct acctttagtt
    41641 tcaattcaag accgtgcaaa tgttgcacga aaaaataata aaggaaacat tggaaatcat
    41701 ccactttata catgtgtttt ttatagtgat ttagagcgtt taaaaatgat taaagaaaaa
    41761 gaaatggaaa atagaatgga ggaagcatta aataataacg aatttatagt atatcttcag
    41821 cctaaaataa gcctcaaaga taatactatt gtaggtgcag aagcattagt aagatggcaa
    41881 gacccaaata aaggccttat accaccagac gagtttattc ctttctttga aaaaaatggt
    41941 tttattacaa aactcgacca ctatgttttt gaaaaagtat gtagtatgat aagaaaatgg
    42001 atagataatg gagaaactcc aatacctgtt tcagttaatt tttcacgtgc taatttaaat
    42061 aatatagatt ttttagaaaa atacagaatg cttcgtaata aatacaacat tcctgctaag
    42121 ctcttagaaa ttgaattaac tgaaacactt gtatttgaaa atctccaaaa attaattaat
    42181 ataatagacc aaatccatga agaaggtttt caatgttcac tagatgactt tggaagtgga
    42241 tactcttcac tcaatatgtt aaaagaaata aaagttgaca cattaaaact tgaccgtgct
    42301 ttttttagct cacctaatgc agataatatt gctgaaaatc atgtaataga atctatagtt
    42361 aatttggcaa aaaaattaaa tatgaatagt atatcagaag gtgttgaaac aatcttgcaa
    42421 atggattatc ttaaaaaaat taattgtgat atgatacaag gatatgtttt ttcaaaacct
    42481 ctacctcaag aaatatttga gaaaatgact tttggaaaaa aactagaaga aaccagtatg
    42541 gatagttccg tttaaataaa ataaaaaact tgtctctata aaataatttt aatcatttta
    42601 taaagacaag tctttttatt ttccaattta attttatttt ctaaatttct tacactcggc
    42661 ttgttttaaa ttcccttttt aagaataata atacgattat catagcaata aaatctgcaa
    42721 ctggctgtgc caaccaaaca ccatctaaat taaattgaat tggaagtaca atgattaatg
    42781 gtataaataa aataaattgt cttaaaagag ttaaaaacat tgaatgttta actttactta
    42841 tacactgaaa atacacaggt cctacaatag aaatccccat tataggcaat gtaattagat
    42901 ttaggcttat acctcttact gctatatcca tcaaatctga atctttatta aatataccta
    42961 caaatacttc tgggaaaact tgtactacta aaaatccaaa tgacaatatg acaactgaca
    43021 ctatgataga taatattaaa gttttctttg cacgctcata ttgttttgca ccataattgt
    43081 atgatattat agtttgcata ccttgattca atccaaacac aggcatcata aacatcaata
    43141 aaatagatgt aagtgctgtc atagctccaa tagctaaatc tccaccataa acctttagag
    43201 aattatttgt aaacatgtga gttatactta tagctacttc catagcaaaa ggtgtcattc
    43261 ctattgcaaa taccttcttt actatatctt tattcaattt taagttacat ttttttagtt
    43321 ttaaattgga cttccctctt ataaaataat gtattaccca aaaaaatact actatttgac
    43381 agagtactgt tgctatagct gctcctttta tacctaaatt aaatacaaat ataaatatag
    43441 ggtccaatat caggtttaat acacatccta caatcattgt ccttgctgct aattttggat
    43501 taccttctgc cctaattgca ttattaagag aaaatgcaac taaattaaat atacttccaa
    43561 ccaatatgac actcatatag tcttttgcat aaaatattga atctttactt gcacccaaaa
    43621 taaaaagtat ctcttctaag aaaactaatc ctaatatagt tataattaaa gagataatta
    43681 tagataatgt caaagcatta cctaatatct tctctgcttc ttctctattt ctttccccta
    43741 actttataga caatcttgtg ctagcaccta ctgataccaa cattccaaaa gctattatta
    43801 gagtaaatac tggcatagtt acaccaagac ctgcaatagc tatagagcca ataccttcca
    43861 tagaaccaat aaaagctcta tctactacat tataaagtga agttaccatc attgctatta
    43921 ttgcaggtat cgaataccta aataataaaa tccatatttt ttcatgtctt aatgcttctt
    43981 gattctccat gttgtcacca tttacaccat gtcataagtt atacaaattg gtttatttgt
    44041 tcttgggtct gttgctattt ctgcatcaat attaaataat tcttttagat tatccttcgt
    44101 cataacatca tatgcatcac cttcacaaac tattttacct ttcttaatac ctatcatgtg
    44161 gtcagcaaat cttgctgcat tattaagttc atgtattacc atgacaatag ttcttccttg
    44221 ttttttattt agttcatcta ataattttag tatctccaat tgatgtgcca aatctaaata
    44281 tgttgtaggt tcatccagta ataatatatc agtttcttgt gccaaagcca tagctatcca
    44341 tgccctttgt ctttgtcctc ctgataaatc ttccatattt ctatccttaa attctgcaat
    44401 tccagtaact tctaaactcc aatttacaat ctctctgtct tctttactag aattaccaaa
    44461 tccactttta tgaggaaatc ttccataaga aattaattct gaaacggtaa gaccactagg
    44521 agcttgaggg ctttgtggaa gtacagccat atcttttgct atttctttag acttcttttt
    44581 gtagatgtcc tctccattta tatatatttt cccactatta gggctaataa ttctacctat
    44641 agttttaagt attgtcgatt ttccacaacc attagcccct atgatggtag ttatttttcc
    44701 ttttggtata tttaaattta aattttttat aatatctgtg tttccatatg atacatttag
    44761 attcttagta tttatacagt tcataacaac accctttcct aatcatttac caacattaaa
    44821 taaataaagt acggcactcc tattatagaa actactatac ctactggtat ttctataggt
    44881 gctagaagat ttcttgatat agtatctgct attaaaagta ataatgttcc tatcaatgct
    44941 gatactggta ttaatctttt atgctttggt cctattattt ttctacctat atgtggagct
    45001 attaaaccta aaaatgaaat actacctgct actgctgtcg atacaccaga taaaattact
    45061 gcatatatta taagtcttct tctttgtttt tctacatcta caccaagact tatagatact
    45121 tcatcaccca aatttaaaac atctatatat ttagatttat aaatagttat acccataaaa
    45181 atcactataa atggaagcac agctattaca tatttccaac ttgttcccca aatgcttcct
    45241 gatgtccatg ccataaccct attaaattct tgtgttgtaa atttcaattg gaatatcgtc
    45301 aaaattgaag taaaagctat gtttacacct ataccaataa gtagtaatct tgacgaattt
    45361 ataccacctt tccatgcaag agaatatata agaaatgctc caaataaagc tcctataagt
    45421 gcaacaatag gcattgtaaa tacagtcaag ttactcatac cttcatatac attaccattc
    45481 ataaggtata tataaactac tacaaacaat gcagcacctg aatttattcc caaaattcca
    45541 gaatcagcta aatcattctt tgtaactcct tgaagtatta cacctgctgt tgataatgca
    45601 gaaccaacca aaagtgctat tactattctt ggtaatctta atttaaatat tgcaatttca
    45661 tgattacgct gaccctgccc taaaaaagtc tttataacat ccattggttc tatagaaaat
    45721 gagcccatat ttaaactcaa taaaaaagtg ataaaaataa gcaccattaa aattgatata
    45781 acaagtaatg ttttagaatt tatttttata atatttttca tagtacctat ttctccccct
    45841 ttctaacaag gtatataaat attggcactc ctataagtgc tgttatagaa cctactggtg
    45901 tctcatatgg aggatttatc atcctactta atatatctgt atatacaagc aatacagctc
    45961 ctaatactaa agagctcggt attatatact tataatctga acctactatt cctttagcta
    46021 tttgaggaac tataagacct ataaaaataa tattaccaga cactgacaca gatgctccag
    46081 tcattaatat tacaagtact atacatataa atctaacaaa cttagttttt tgtcctaatc
    46141 ctattgccac ttcttctcca agacttaata tagttattct tggagccata ataatagcta
    46201 aaataaatcc aataccacca gctacaaata gcaattttat accttcccac ttcactccta
    46261 caagccctcc tgatatccag aaacttaatt gttgagatag gttaaaatac atagatattg
    46321 ctgatgccaa agaaattagc aatgtaccaa gagcgactcc tgcaagagct aattttacat
    46381 tattaactct tcctcttgat ttagaactta taaaatatat aaataatcca cttatacttg
    46441 ctccaataaa tgcaaacatc attacactaa aacttccatg tataagttga ggaagttttt
    46501 tttgaagtac cagtgatatc gaaattgcga atgtagctcc ttgtgtaatt cctataacag
    46561 atggttcagc tataggattt ctcgttattc cttgcattat tgccccagaa actgctaaaa
    46621 accctccaac aagtgcagct gctattgccc ttggaagtct aacatccttt actattctca
    46681 tatttattcc atcttccatt tttatcaaac tatctataac agttgataga ttcatatctt
    46741 ttgccccaat agttatggat aatacaattc caaatacaag tacaactata cttactaata
    46801 tcaacaaata agttatattt tttttactca gcttagtcaa ttatcctacc tccttttccc
    46861 ttttaatcgt cagtataata tcatctatta agtattttaa ttttaagatt tattaaaaat
    46921 aggtgtgaaa aatgaatatc attatctcac acctactaag ttaagaatta ctttgttaat
    46981 tcatttttaa ctgattctaa taataactct tttccaattg gattgtatga ttgactgaaa
    47041 aatggagcag catcaagtat tgttacatta ccatctttta ctgctcttat ttgagcccag
    47101 atagcactat tttctaaatc ttttttatct gcttctgtag caattacaac tatatggtct
    47161 gcatctatat ctgttaaacc ttccatactt accattggta gtgttattcc atcctgtttt
    47221 ggcatattct taggtctagc taatttcata tcatcattga ttagagtacc tattccacca
    47281 tcactaaata ccataaattg acctgaactt gccaacactg gtaaataagt tttttctcca
    47341 ttcttttcta taacttcctt acctaacttt gtagcttttt catcatactt ctgtagccaa
    47401 cttttatctt cttcttcttt gtcaaataac tttgaaacat cagttaactt gcttctccag
    47461 tcatttgcat aatctttcat cataactaca ggagctattt cttttaattg gtcatatatt
    47521 ttttcttgtc tttgactcat tattattaaa tcaggattta cttctaatat agcttccata
    47581 tccatagtat ccatcattga gtgcccaact atctttacac ctttaagctc ttctcttatg
    47641 taacttggta atttatcagt ttcatatgag tctacatttg ctgttgcaac aggcttataa
    47701 cctgctaata atagttcttc actacttcct gatatatcaa ctattttttt aggatttgat
    47761 ggtatcttaa cctctccttt aacagattgt acaactcttg tctctgattt atctttatcc
    47821 tctgtattct tatctgaaca tgctgtaaca agtactaacg tagttataat agatataaat
    47881 attgcaagtg attttatttt tttcatgatt acttctccta cttgtttatt atacttacat
    47941 gatattgatt atcataagca catatttatt atagcatttt tctattttta gtcaatatta
    48001 ttttgtaaaa ggataaaaat tcctaattaa tcttaattat atatagctta gataaggttt
    48061 tcttatatta aacagtattt tttttaagaa ttggacacaa atacaatgac ttttcagtta
    48121 aacaatgata aaatgcaatt tatagataag gaatttagta gggaggattc aaaacatggt
    48181 acatttagta tattgtgata atgcaggaaa aaaaggagaa aaggtcttag ataaaatctt
    48241 ggatggaaca aaaacaatgg ttattagagg tgctgctggt agaaaaatac cacatagtag
    48301 agtatttgaa gatgagttac tttattttat ggaaaaagga actgcaaaaa tatctgcaaa
    48361 agccactgtt aaaaaggtag aaaactatgt taaattaaca gaagatgaaa tttctaaaat
    48421 tttaaatgaa aatcaaccaa aattaaattt atctgaaaag caaaaagttc gttggcataa
    48481 aaaatgttta tgcttagttg aatttgaaaa tgttgaagaa ataacacctc ttgattttga
    48541 ccatcaagga aatatggatg attggcttat tgttgaaaaa attgaagatg tagttgttgg
    48601 tactagtata ccttacaatt atgagaagtc taaattctaa agtatcaata acataatact
    48661 atattgctaa actctactta aataaaaaaa gagtgcattt aataattata aaaattattt
    48721 ttatacactc ttttttaata ataattttaa attacttact ttctaatctt tcatatacat
    48781 ctataaattc ttctgctaat tgttgaaaat tcatagctgt cattaaatgg tcttgtgcat
    48841 gaataagtat aacacttatt tcagttttat taccattagc ttcattttgt atcaattctg
    48901 tttggaattt atgagcttta tgaattgatt ctttcgactt ttcaatacat tctctagctt
    48961 tatctatatt cccgctcttt gcttctttta ttgcttcaaa tgctagccct ttcgcatcac
    49021 ctgcaaatcc aattattcca aaagatatct ctatcatctt ctcatccatt tattcgacct
    49081 cctaaatatc tctatagctt gatatgacta atccattctt ttctaaaaat tctttgactt
    49141 ttttagatgt aagtatcttg tgctctttcg ttctatcaat agcataagat gtagaattta
    49201 aaatataatc atctaaaaaa gctgggtgag acataatatc cactacatca tacttcatta
    49261 tttcgtctat attttttata aaatattctt cacttacatt ttccttataa aaactatcta
    49321 ttaaaggaac tactttagaa tactctaaat tatattcaaa tccacctctt attggaagat
    49381 tatacttggt tacaatcttc tctattactg gctttaaact tactaaagta tggatatgat
    49441 ggtgactatc taaatgagat atatctattc caagcccttt taccctatct atttgagcac
    49501 aaagttctct ataaatctca tcacaatcca ttttttcaat aatttcgtct gtaatcctcc
    49561 taataaaaaa accgtcttta tcaacaatag tttttaagtt agataataat ggtctaccac
    49621 aacttaaagt catatgaact ccacaattta aagttttatt ttctttaagt aagcctactc
    49681 catgttctac cccaggcata tttgccatca tagaagtaga cctaactata ccattattat
    49741 gagctgaaat tattccatag ttcacagctt cacaatatcc aaaatcatct gcatttatta
    49801 taattttagt cataccataa cctactttct atagacaact atctattaaa tctaggaaga
    49861 taatctttat gagcttccaa catttcgtct aatatagttt ttgctaagtc atcagatgga
    49921 atcaatgggt ttatacaaag tgccaaaaga gcagattcat aatcgccata tacagctgct
    49981 ttagctgcca atacttcaaa tgatttgatt tgacttacta atccatgcac agaatctggt
    50041 aaatatccta tacttattgg ttttggacca ttttttgtta ttacactact tacttctact
    50101 gcttgttcat ctttaaaatc tcttatagaa cccttattta atgtattaac tacttggata
    50161 tcttttttgt cattgtatat agaacttatt aaattacaag cagcatcact atagtaagcc
    50221 cctcctcttt tttcaagttg aggtggtttt acatctaatt tttcatcctt atataattca
    50281 aataattgtt cttccaattc tttaactact tgacctctag cttttccctc tttaaactct
    50341 ctcaactcat cctcaagcat ttctttagtt ttatagtagt atctatggta tggacaaggt
    50401 attgcaccca aagattttac aaattcagca ttaaaatcaa ttgcctttat attttgcata
    50461 cttatatctg ctttgacaaa tttatcaatt gcttcttttg taacatcttc tccatctaaa
    50521 gatacattta gaccataaac catatgatta agacctgcaa aatccatact tattctgtca
    50581 ctttctacat taaatagttt ggcaacatca ttttttaaat gaattggcac gttgcataga
    50641 cctatatatc ttctaaaatt agtatatttg aatacagcct ctgttattat tcctgttgga
    50701 tttgtaaaat tcaccatcca tgcatttgga cataattctt ccacatcttt tattatatca
    50761 aatataactg gtattgtgcg aagggcttta aataaacctc cagcaccatt agtttcctgc
    50821 cccataactc catgagataa aggaatagtt tcatctttta ttctcgcatc taaaagacct
    50881 actctaagtt gtgttgtcac aaagtctgca tctcttagag cttctcttct atctaaagta
    50941 agatttattt tcatatctac tccagctttt tttaccatcc tcttagctag atttccaact
    51001 atctctaatt tttcttttcc agcttctata tctacaagcc ataattcctt tacaggtaac
    51061 tcttcatatc tatttataaa accctctaca agctcaggag tataacttga acctcctcca
    51121 attgtaacta tttttagtcc ctttttcatc tcattatacc atccttacct ataatttaat
    51181 atactctaca aaaccccata catttattta aaactctata catttattta ccgaaataaa
    51241 actacctagt tgttaatttt caatttatta gcttccattt tttcagacgc tatgacaaat
    51301 ggaatatata ttaatattga taatattaaa ttaaatagtg ctaaagctcc gccagtccag
    51361 tcacctgtag ccattgctcc acctaatata ggaggtgtta cccaaggtat tttaggtaaa
    51421 attactggtg ctactaatcc aaaatctatt gctaagtatg atacagcact acatattact
    51481 ggtgcaagta caaatggaat cataaatata ggatttaaaa ctattggaag tccaaatatc
    51541 aatggttctc ctatgttaaa tattgcaggt ggaccaccta atactatcat ctctttacgt
    51601 cttcttccag ctattaataa agctactatt aatcccaata ccattccaga accacctaaa
    51661 tatacaaatg catcaaagaa tgcacctgca agtacatggt atccttccgt tgctcctgct
    51721 tgagccaagg cagcattttc tccacctaat ttcataagta tagtttctgt aaaaggaagt
    51781 gctatatttg caccatgaag tccaacagtc caaagtatat gaattataaa tgcaataagc
    51841 attgtagaac ctagactatc agctacattt gatagtggtg ctcctaaata agtatttaaa
    51901 atatctgtta agaaacttcc attagaaagc atttttataa atattcctat tacagtaaat
    51961 atcattatag ttaacattcc tggtattaac tttgcaaatg atcttgaaac tgctggtgga
    52021 actccatctg gcatttttat agttaatttc tttaccttag ataatcttac aaatatctca
    52081 gttgataata atcctattaa tatagaagag aataaagctg ctgtacctaa gtaggtttgt
    52141 tgtatcattc cccatccttc aactactgta gttcctccct caggaactat tttaccaatt
    52201 tgtggagcca ttataaaaaa gatagataaa gctataagcc cagattgtaa cccatcactc
    52261 tcataagatt ttgctagaaa ataagcaaca cctattacta agaatactgc cattgtacct
    52321 attgctcccc accaaaggtc gcctccaaat gtggtccagt tttctccaaa tatacttgcc
    52381 atcaaatttt tgtatgcttc caatggtaag ttatttatca atgttcccaa tgcacctacc
    52441 atagttatag gtatcattac tataaatgca tctcttactg ctactaagtg cctttgagct
    52501 cctattttag cagctacagg cactatatat ttatccataa atgacatgaa tttttccatt
    52561 ttacatcctc cagtacaact ttattttgaa ctatttaact ctacagctct atctaacaca
    52621 gcttttccat tacatcttcc ataatccatc atatttataa cttctactgg aatattatat
    52681 ggttttgcca tttcagttgc ttttcctaat acatatctaa cttgaggccc taaaagtaag
    52741 acatcacaat tttctatttc attttttaag ttcacttctg atatagccca tatttttgct
    52801 tctataccgt tttcctttgc tgcatcctcc atttttgtaa ctaataaact agttgacatt
    52861 cctgctgaac aagctaacat tatttttatc attttttccc ctccaaatta gattcattaa
    52921 atatttttta agtcataagt tttttaaact atacatttaa aatatgtttt tctattaatt
    52981 ttttcttaat gtatatatct tatttttaaa tgtatataca tttaattctt gatattatta
    53041 tataccaaat gtatatacat ttcaagaaaa ctttttcatt ttatttaaat tttattcgac
    53101 aacagcattc aaagttaatg tatatccata gtgatatgtg tgtgagtact caaaaatctc
    53161 actattttgt aacttacaaa tttggcttat atataaaagt ggctctggtt cttctaattt
    53221 tagattatcc atacactctt cattcgatat tacagcttgt acttctctct ctgacatggc
    53281 tatcttgtat tcacacactt cttcaacaaa attataaaga gaattttcac aatgagtctt
    53341 atttaaattt ggaaataact taactggcat ataagtaatc atatatgaaa ctcttgcatc
    53401 attggctaat cttactcttt ttatttccca aacattttct tctaaactta tattcaactt
    53461 acttgataaa ttttcatctg cctgaactat ttcaagagat accaatatat tagatacttt
    53521 atagccttta ctttccatct ctttagtaaa tccacttaca gacgatatat tatcatatat
    53581 attatttgca ataactatac tacctacacc tctttgtcta gttatatagc cttctttaac
    53641 tagattatta agtgcagacc ttacagtcat tctagttaca ttaaattctt cactcagctg
    53701 tttttcagaa gggattaaat ccccttcttt caaactgtct gaatttatta actctctaac
    53761 atgattttct ataactttat aaattggctc tttcatttaa ttcactcctt attaaatctt
    53821 ttatataata agataatttt atatacaaac aaagaaaatg tctatacatt taagataatt
    53881 taaattttat tcagaaatct tgtacaactt tccgagtttt aataaagata taaatagact
    53941 tatcattaat atacctttta atatacttga taaggttata ctccaccata caccatttag
    54001 acccaacatt tctggtctag atataaagta agccaatggt actcttgcac cagtcagtat
    54061 agtaattata atagaaggta tataggttct ccctaatcct ttgaaagctc ctgttgttat
    54121 tatttctaaa cacataaaaa attgagaata gcctaatatt ttaagataaa ctgctccttt
    54181 ttctattgcc tcactttcat ctataaaaat agaaaatata ctctctcctg caaacactaa
    54241 tactaaagta gttattatac caagtacaga agatacagtt atagctattt tgcaaccttt
    54301 atttattcta gaatacttct tggcaccata attttgtcca acaaaactgc ctaatgcaac
    54361 tgatagccct tcagccgtca tccaggaaat tgcttctatt tgtgagccta ctttttgtac
    54421 tgcaacagcc acaggccccc atgatgctac tattactcct aatagcattg agaatactgt
    54481 aaacatacca ctttgtattg ctataggtaa tcccaattta tacagaactt tataatattt
    54541 agtctctatt tctttaaata gtcttaattt aaaatattct tctttacttt taactattat
    54601 atatataaaa catgtagtaa ctactatctg agcaaataca gttgcaatag cagctcctgc
    54661 aacaccaagt tttggagcaa atccccatcc aaaaattaat atagggtcaa gtataatatt
    54721 agttattaat cctactgtat taatacgaaa aggagtttta ctatttccaa gaccattgaa
    54781 aattgcagta aatactggat taataaaata aaataccata cctagagcta ctattatcaa
    54841 atactgtcta gacatggtta taacttctaa gtctcctaat ctaaaaaaac ctatcaattg
    54901 tttattaagt actattaaag aaattgtata tattattgct agtataatat ttatttctat
    54961 tgctgacttc atatatgatt tagtagtgct tatattattt gcaccaatac tttgtgctac
    55021 ttttatctct ccacctactt ttgaaatcat aataaatgcc attgcaagcc atggaaaaaa
    55081 accagctgtt ccaactgcag ctactgcttt acttccggct ttaccaaccc atatcatatc
    55141 tatcatgtta taccccatct gtataaatga agtccccatt attggaagtg atagcttaag
    55201 taatttttct gtaattcttc cttctgttaa attaagtctg tctttcattt tccacctctt
    55261 ttatattaaa tttatttgct tatatagcta gattaatcat tttatttgat tgagttcact
    55321 atccttcaat ttatattatc atatctcagg attgcatctc aatcatactt atgtttaaga
    55381 tacagtattt tacctatcta tgataaaatt aatacttatg aatataaatc tagccatttc
    55441 atcaatacat attctaaccc ttaacttaac ttcaattaag tatacatatc gtaaccaatt
    55501 agaatatttt atacggtatc ttccattaat aaacaaccaa tatcaatgat ttatatataa
    55561 ttttatttat acataaaata gtatactata ataataaaaa aactatattt gaatgcttta
    55621 agcatgttta ctaattgtaa tttccacaca aatttgataa tatatgaata tattatggtg
    55681 aaatttatag atatatatta attatgggga gattgtggga ggttcttttc acaagacatt
    55741 taagctatga aaataaataa aaaattcaat agagttgata tgcaggtttc aatacttact
    55801 gcaattattg taataatatc ttcctcatgt gtatattttt ttaattatac actaacttat
    55861 aagagcatga tatactcttt aagtgagagg tcaaaacata tctatgaata tgtagaaaga
    55921 aatattgata aaaatacctt tactgaaatt aattctaaag aagaccaatc aaaaaagtct
    55981 tataaaagtt ctaaaatcct tttagaatct gtaaaaaata ctactggagt catgtatcta
    56041 tatactgcta aaaaaacaaa agatggatca ctagtatatg ttgttgatgg tttaaattca
    56101 tctaggagtg attttagaaa tgctggtgat ttgatagaaa aagagatttg gggagacctt
    56161 aacaaagcat tagataatca tatattgtta cctaaaaaga ttaaatcaac atcttgggga
    56221 tacatattta tatcgtattt tcctattcac aatgatgttg gtaaggttgt tggagtaata
    56281 ggaattgaat ttgaagcaaa acatcaatac aatacattta aatttataag tatagttaca
    56341 ccaataatag cattattaac ttgtctaata tcagcattga ttgcagtgat tctatttaaa
    56401 agaatatcta atcctacata tactgatttt gctaatacag attatttaac aggcctaaaa
    56461 aatagaaatg cttttgaaat agatatgaat aacttaaaca attcaaatct aaagaatcta
    56521 atatctatca tatcaataga tttagacggt ttaaaaaaga ttaatgataa atttggccat
    56581 cagacaggag acttatatat taagcaagca agtaaaatta tacaatatgt aataaataaa
    56641 aaatatatag tttatcgtat tggaggtgat gaatacataa ttattctaaa aaatttatct
    56701 cacaaagaaa taaataatat tataaataat attaatttaa aaatagttga agaaaactca
    56761 actaatgaat taaaattatc aatgtctatt ggatatgcta tttttgatga aaaagtagat
    56821 gtttctttat ttgatacata tcgtcgtgca gattctcaaa tgtatgataa caaaaggaaa
    56881 attaataaac aatatcaata ataaatttaa aaagtctatt ctttaaataa taaatcacaa
    56941 gaatagactt ttttaaattt gtgtttttat aagataaatt atttaattaa agtttgttct
    57001 tttttctaaa cgattcttta taaattcata tattactttc actaatatat ttgtgactaa
    57061 tattaacaca gctagtgctg ctgcctgtgc agtactcccc ttatcatcta gttgtacaat
    57121 tgatattgca gctacttttg aacttgcagt atatataaaa actaatgctg atattgtcac
    57181 catggagttt aggaaaaagt acataaagtt ctctaaaact gctggcaaac aaagtggtat
    57241 agttacgttc ttaagaattg atgcgctgtt tattcccatt gatttagcta ccatatctaa
    57301 ttctttatct actttcttaa tagcagtagt agctgttata aatgctactg aaaagaaatg
    57361 aactatatta catataacca ttataagtaa tgttccatat aatccattaa acaaattctt
    57421 aatgtatatt gtatccataa aattaaactc taatttatta aaaaataata cataagctat
    57481 acctaaaact aatcctggca atgccatagg caatgtactt aaaaaatacc caaatgattt
    57541 taaatatgga gctttttctg ttttttcatt caaatatgca aataagaaaa caaagctcgt
    57601 ccctagaata gctgtaaata gtgacatttt tattgaattt ataaatggtt taatcccatc
    57661 aatactgttt ttcatagaaa aatgttccag tgtcagtctt aaatcatatg gccaaactga
    57721 tattaatgaa gataagatta cagttaacat tacagctatt ataccaaatg caataattcc
    57781 tacaacccct cctaaaatac tatctcttaa cttattagtt ttaaccttat atggaattga
    57841 ctttgaagtt atatatgaat tttgattttt ttcaattttt ttagttacta taaacgatat
    57901 tattgcaggt attaaaagta atattgatac agttgctccc attggcatat tctgttgccc
    57961 tataatttgc ttatatacat ctattgataa tacattaaac tctcctccta tcacctttgg
    58021 agctccaaaa tctgtaaaac ataatgtaaa cgatacgaat gcagaactta ttaaagagta
    58081 ttttatactt gggattgtta tgcttataaa ttctcttatc ttgcttatcc ccatagtatt
    58141 actagcttca tatagtctat aatcggttga acttagagat atataaagta tttgaaatga
    58201 ttgaggaaat acatatataa tttgtgccaa tattattccc actgctccat atattggaac
    58261 atgcactcca agtaaattag ttaccaaacc ttgatttcca aataaatata ctagacctat
    58321 tgcatgcatc attgttggag caaacatagg aaacatagct aatgatttaa aaaaaccttt
    58381 aaatttaatc tttgttctag ttaatgcata tgcatatact aatgcaagtg ttagtgatat
    58441 tacagttgat ataactgata caaatactgt attttttaga gaatttaata gagattcaga
    58501 agccaagtat tcttgaaagt tttgtaatcc tacaaagact ccatctttat ctaaaaaagc
    58561 ctgtacaaat agatatatta taggtgctaa taaaaatatt actaaagaca taactaatac
    58621 tgtaagcata cattttttta tatctaaatt catttttgat ttaagactta tacttttaga
    58681 acttatagca ttattattca tacacttatg ctcctttaac ttttggatac tttaaatagt
    58741 atttttcgtc tatacttatt tttacaaggt caccttctac taaatttaaa ttaacccact
    58801 cttttataga aacatcactt attatgaaat tttcatttaa tttatctttt atttcaactc
    58861 tcaataaatt ccctctaaac tctatatttg atattatccc ttggtagttt tcttttgtcg
    58921 atttctctat ttgaacatat tctggtctta cagttaatat agaatctcca ttatcaaaac
    58981 agtttgtatc tcctataaat tgagctgtaa ataggttttg aggattttgg tatatttctt
    59041 ctggagtccc tatttgcatt atatctcctc catttagaat agctatttta tctgccatag
    59101 ttatagcttc ttcttggtca tgtgttacca ttattgtcgt tatattaagt tctttttgta
    59161 atcttttaat gtccattcta agcttgtgtc taacctttgc atctaatgca gacattggtt
    59221 catctaaaag taaaaacttt ggttcaagag ctaatgctct tgctattgca atcctctgtt
    59281 gttgtccacc tgataatgct ttagggtatt tatgagcttc attagtcaat ccaactgttt
    59341 caagtacttc cttaacttta ttatctattt tttcttttga aacttttctc tcttttagtg
    59401 gaaaagctat attgttataa gcagtcatat tcggaaataa tgcatatgat tgaaatacta
    59461 taccaaaacc tctctttgat ggctctaaat ttgtaatatc tttatcctgg agaattatag
    59521 ttccactatt tacatcttca agacctgcta ttattctaag taatgtagtt ttaccacatc
    59581 cactaggtcc gagtaaacat agaaattccc cttcttcaat atccaaacta atattattta
    59641 aaaccttttt ttggtcataa cttttaaaca cattatttat ttttaagtaa ctcatatctt
    59701 atctctcctt atatagttat ttttttattt taaattttat atcctacttt ttcttctaaa
    59761 attctttcat ctaaattatt aatttaaact ttacttactt tcagattttg aaccgtattt
    59821 tgattcccaa gttttaagta ctgtacttct gtttttggca gcagagttta aatcaacttc
    59881 ttttataagc tgttcaaatg gttgtttaga ataacctttt ggaactggat tatctgtctt
    59941 tatggaagta actgctactt catgtgcata tctatccata gctgaatcac ttattgccca
    60001 atctaaaaat agctttgctt ctttttttat attatctttt ttaactaagg catttgcttc
    60061 taagtcccaa cctgaacctt cctttggaaa tacaacctct ataggttctc cactagataa
    60121 ttgttgtgta gctctatatc caagtgtaat acctattgga tactctccag agccagctaa
    60181 cttcgcaggt tttgaacccg agtgtgtata tgtggctata tttttatgta atttatccat
    60241 gtaattgtaa gcatcttttt cacccatcat ttgaataagc cctgatactg taagataccc
    60301 cgttccagat gatgctggat ttggcattgt tataagtcct ttatattctg gttttattaa
    60361 atcttcataa ctttttggaa tatctatacc tagtttctta agttccttat aattaactac
    60421 tattgctgtc tctgggacac tcattcctac ccaagataca tcatcttcag tatctttaaa
    60481 ttttttatca actttatcat aatttttagg cttatatgct tcaagtgcac catctttttt
    60541 tagctctatc atgttcattg ctgataatcc ccatataata tctgcttgtg gattatcttt
    60601 ttctgctaat agttttgaag ctattacacc atgagaatcc ataactatct ctacatctat
    60661 attgggatac tcttctctaa aaccttccat ataataagct atctgctctt cctctagtgc
    60721 tgcatatatt gtaagtttat tatttccttt tccttgagta gtttgtggtg ttgttgatat
    60781 gcaacttgtc ataaatgtaa tcactacaat gcacagacaa gtaaatataa attctttcat
    60841 atcttccccc tttgtgtttt ttcctttttt tatttgtttt ttattgtttt tgcttatgtt
    60901 tatataatac acctaatttg ttaatataaa gttaagtgta aattaacagt tcgttaattt
    60961 ttagaaattt ttgttaaata tattattttt agttaaatac agtctgtttt taaacaatat
    61021 attaattttt atagtatcta cattttaatt taaacataaa aaataagtct aacctctata
    61081 aagtagaatg ttagacttat ttttataagt atttaattat acaaccaaat catttttttt
    61141 cttttcttca agtgcttttt taagcaccat atccttaacc ttcataagtc tagtagtact
    61201 tgctctctca ttttcttcaa gcttcatagc tatatactta atagtctcaa tgtaatttgg
    61261 tatcattaca ttttcaagag cattaacacg tctacgtgtc ttttctatct cttgtgcaag
    61321 aagctgtgca cttttttcac tttctgcaag tcttaaaagt ggttgcatag catctgagaa
    61381 agcttccata gcagaatcta attcacctga tgtaaaagca agaccataag gataaatatc
    61441 actttgattg ttttcagttt taaagtcaaa cacaggaaca tcaacactca ttatatttct
    61501 cgtagaaaca tctactgaaa ctgattgctt tggcatcata agtgctgaac ccagatactc
    61561 ctgactcata actgctcttg cgattataaa gtttttataa gcagtatcaa gagcattttc
    61621 tgcttcttca cgcaatcgct tattttctct tacaatctca agaaattgtt tcataagttc
    61681 atcaagttta tctttaagaa gcttatgacc tcttgtagca gttttaagga gtttcttaag
    61741 tctagtcatt tccatacgtg ttggatttat atttaatcta gccacagata tcactcctta
    61801 ggcatatatt tttcaaaata ttcatcacgg atacgtttaa gttcactttt tggtaacata
    61861 ctaagaagct tccatccgat ttctaatgtc tgctcaatag ttctatcagt tctaaatcct
    61921 tgtgaaacat attctttctc aaattcatct gcaaacttag catacattaa atcaatctca
    61981 gaaagtgcag attcaccaag tatagccata agttcttttg catccttacc tcttgaataa
    62041 gctgcaaaaa gctggttcat tgtatctgca tggtcttcac gagtcttacc tttaccaata
    62101 cctttatctt ttagacgaga aagtgatggt aaaacatcta taggaggctg tatatctttt
    62161 ttataaagtt cacggctaag tataatttgc ccttctgtaa tgtatcctgt aaggtcagga
    62221 attggatgtg tcttatcatc ctcaggcatt gtaagtattg gaatcatagt tatagaccct
    62281 tcatgccctt tcatttttcc tgctctttca tacatagtag caaggtcagt ataaagatat
    62341 cctggatatc cacgacgtcc tggaacttct tttttagctg ctgaaacttc acgcaatgcc
    62401 tctgcatagt ttgtaatatc cgttattata acaagtacat gcatatcttg ctcgaaagca
    62461 aggtattctg ctgctgtaag tgccattcta ggtgtagata cacgctctac agctgggtca
    62521 tttgcaaggt ttacaaacac tacagaacgg tcgattgcac cagttgcttt aaaatcgctt
    62581 ataaaaaatt cagcatcttc aaaagttata ccaactgcag caaatacaac ggcgaactta
    62641 gaatcagttc cacgtacttt tgcctgtctt gcaatctgaa ctgcaagatt ggcatgtggc
    62701 aaaccagacc ctgagaatat aggaagtttt tgccctctaa ccaatgtatt aagtccatct
    62761 atagcagaga ctccagtttg tataaactcg gccggataat cacgtgctgc tggatttatt
    62821 ggagctccat ttatatcaag tcttttatct ggtataattt ctggacctcc atcaataggt
    62881 ctacccattc cactaaaaac acgacctaat atatctggtg aaactccaaa gtcaagactc
    62941 tttcctaaaa aacgaacttt actttcagca aggtttatac ctgttgagct ttcgaaaagc
    63001 tgaacaagtg cagtatctcc atttacctct agaactttgc aacgacgaat ttctccattt
    63061 gaaagttcaa tttctccaag ttcatcaaat tttacacctt ctacgccgtt tattaacata
    63121 agaggaccgg ctacctcttg tattgactta tattccttta tcatagttct tcagcccccc
    63181 tctttttaat aaggtctgca agctcgttgt ctatttcatc ttcaattgaa tcgtaagctg
    63241 catctatatc gccttcttct acatacttag cacgaccaat cttttcaaga actgaaagct
    63301 tgataatatc gtttatagta acattttgct tgatagcatc ttgtgctgac ttatagaatt
    63361 ttaatataag tcccatcatt ctatattgtt tatgaagtga tgtataagta tcaacttcat
    63421 ggaaagagtt ttgatgaagg aagtcttctc ttatagaacg agtaacctct agtatcaatc
    63481 tatctccatc tgaaagtgaa tcaaccccaa ccaattgaac tatttcttga agttcagatt
    63541 caacttgtaa aagtttcata gcttgagctc tttgagctga gaaattatca tttacatttt
    63601 tatctgccca tacatcaact ttttcctgat agagtgaata actagtcaac cagttaattg
    63661 ctgggaaatg acgtttatat gctaaagatg catcaagacc ccagaatact tttactatac
    63721 gaagcgttgc ttggctgaca ggttctgatg tatcaccacc aggaggagaa actgcaccaa
    63781 ttgctgtaag tgttccttct ctttcatcca tacctagaca atttaccttt cctgctctct
    63841 catagaattg agcaagacgt gaacctaagt atgcaggata accttcttca ccaggcatct
    63901 cctctaaacg accactcatc tctctaagag cctcagccca tcttgatgta gagtctgcca
    63961 taagtgcaac actatatccc atatctctaa aatattcagc tattgtaata ccagtgtata
    64021 tagaagcttc acgtgcagca accggcatat ctgatgtgtt tgctataagc acagttcttt
    64081 gcataagtga ctcgcctgtt cttgggtctt ttaattcagg aaattcaaga agaacatctg
    64141 tcatttcatt tccacgctcg ccacagccta tatatacaac tatatctgca tctgcccatt
    64201 tagcaagctg atgctgtgta acagtttttc cacttccaaa aggtcccggt atagctgcta
    64261 ccccaccttt tgtgattggg aaaaatgtat ctataactct ttgacctgta acaagaagtg
    64321 aatctggtgt tttcttttct ctatatggtc tttcttttct aactggccat ttttgcatca
    64381 tagttacagg tatatcatta cctttttcat ctgtaataac acaaactgta tcttcaacag
    64441 taaattcacc agaatatatt tcttttatag tacccttaac tccataagga accataattt
    64501 tacattctac tactgctgtt tcttgaacgc caccaattat atctcctgct acaaccttat
    64561 caccaacaga ttttttaggt ttaaattccc acttagttgt tctatcaagt gaagatactt
    64621 caacaccttt agttatatta gtacctgaaa tatcatacat tttttcaagt ggacgttgaa
    64681 taccatcata aatagttgaa ataagacctg gtccaagttc aacactcata ggcattccaa
    64741 gagaaactac ttcttcccct ggtcctagac cggaagtttc ctcataaacc tgtatagaag
    64801 ctttatctcc atgcatttct ataatctcgc ctataagatg tttatctgaa actcttacga
    64861 cgtcaaacat attcgcatct ctcatgccct ccgctacaac aagcggtcct gacaccttta
    64921 caattgtgcc tgttttcata ttctctcacc tgcaatcata tactttatca aaatttaaat
    64981 attccctcct atattttatt agcacatata tttagcacca ataaaatttg agattgtctt
    65041 ttattcaact ttcatctatt ctttaaataa tatatctgca cctatagcac gtttactaga
    65101 ttctcttact tcattcatac ctaatcccat acttcctcca atacctggaa taactataat
    65161 ggcaggaagt tggtaatctt tgtattttgc tattgattct tttgcaagca atgatgcctg
    65221 ttctgtaata taaattatcg catattcatc ttcaaccaac ttatgtatac tttttttaat
    65281 ttcgtcacta tcataggctg ggaagatatc tattccaaga gctaaaaatc ccatgatgct
    65341 atctttatct ccaactactc ctaccttata cataagcatc ccttagcctt tcttttatag
    65401 tatctgcgtc tatattatta agcttactag tcaaaataat tctaattgtt tttatctctg
    65461 attctttagc atataaatat gcaattagtg gttctaatgt aagaggctta aattttgctc
    65521 ctctaacata ttccataaga tagtcatcac aaagtttttc aaagacagta aaaccactat
    65581 ccatgccatt tttacagaca tcagagtaag aagtagattt aaaacatgat gctggagtat
    65641 ctgaggaaaa agcttctaag aatttttcct tatcaagtga gccacctgaa acaaacacat
    65701 tcataaacat atcaaaatct ttcttcatat ttttgactct tataaaactc tttagatttg
    65761 ttaaatcaca aactttcata acataatcta ttacaaattt gttttggctt tctttagcag
    65821 tttctttcat actggtaaag gttgctttat ctagaacaat atcaaccatc tggccatttt
    65881 gtgtcttatt ataaacatca aatgcctcta atatagctga tgacattatc ttaggtaaat
    65941 cactaaaact acgatttgct aaagattctc taagcttaat aagaggaatt gtacctccat
    66001 caattaaata tttctcacca tctacaccag aaatttcttc tttaatcagc acttttaaat
    66061 tgtgatagtc atttttataa agaaatacat caacaaattt ttcttcagga gctagacttt
    66121 taagaatttc atatgtcttt gataattctt gagtcaaaat attctcaaaa ttatgtatat
    66181 tattatttga tgtatcagca taacctgcct cagctataat tcttaaagag tcttcagggc
    66241 ttttggcttc tgccatttga ataaacattt gtctgttaag aagctgtttt tcaagcactc
    66301 ttattcgtgc aacggcatag ggataagttt tttcttctgc cattttttaa cccctcctta
    66361 attaaacaaa atttctgctg caatttgttc aatatattca tgctctactg caattatggc
    66421 ttcaaatgaa taattgtact caatgtcacc ttttttaact atgaaacctc cagtaatatc
    66481 tctagtttca tcagacactt taatgccttt ttttgatagc acatctttta atgttttttt
    66541 atctttttta gataatacta tctctgaatc atctgtacaa tttgattttt caatcatgtt
    66601 tagtataatc tcttcatatt cattatcttt aagatttaaa agtttgtttt tagcttctaa
    66661 aattacctct tctaaaatct cttgtttttt tgataatatt tgctttttag cctccatata
    66721 agctcctgat atttccttag aagccgcttt ttctgcttct gcctctgcaa gctttgtata
    66781 ggaagccatt tccttttcag ctttttcatt agctgaattt acttttaaat ctgcttcact
    66841 tttagcttta tccaatattt cttgtgcttc ttgtttggca tcagctataa ttctgtcaat
    66901 cattttttgt tcattaccca taggagtgct tcctcctttt catttttttt acttatgaat
    66961 tataatttat aattaaccaa ttgcaattcc attgtaagct aagaaagaaa caagtagtcc
    67021 taaaagagca tatgtttcaa ctattgctgc aaatgttata gctttaccaa gttcttcagg
    67081 tctttttgca actattccaa ctcctgctgc tgctgcttta ccttgtgcta tacctgatac
    67141 taaaccaact aaaccaattg gaagtcctgc cataagaagt tgtaaacctt gagctgatgt
    67201 tggtattgca tctccaccaa taatccctgc ttttgataaa ataaggaaag ctatgataaa
    67261 tccatacaga ccttgtgtac caggaagaag ttgtaaaact agaagttgac cgaatttact
    67321 agggtcttct gttacaacac ctgctgcggc ttgacctgct attgaagtac ctttagcaga
    67381 acccatacct gcaaataatg ctgctatagc agctcctgat attgccaaaa attgaccatt
    67441 tcctaacgcg tttaaaaatt ccatatttac atctcctttt tattaatgct tgtatatttt
    67501 gttttatact taaacggaac aaaaggaact cctccgcctt cataaaactt attgaaaaat
    67561 tctacatact gtaacctact tgtatgaaca tatgcaccta gtgcatttat aagaaggttt
    67621 attgtgtgtc ctacaacacc aattacaact gcaagtatcg gaccagctat agcccctaaa
    67681 aggttgataa cttgtgctat aactcctgtt gttaaacaaa gcgccataat tcttgtataa
    67741 gataatatat cagcaaaata acttgttata ccatagagac ttgaaaatcc tttaaaaagc
    67801 ttaacaggaa tacctttaaa gcttcttcct tgagtaagta caagacctat agcacctata
    67861 attgctaaat attttcctac ttctgaaaat acacctatgt cccctgcaac aaaaggtatt
    67921 ataagtagac atacacctgt tatacacaaa taccaaaaac ctatgtcaaa gattgcatct
    67981 attacctttc cacttcttat taatgtatat gcttttattc ccaaacctac atatatatgg
    68041 ataataccga acagtaacga cattcccata agtgtcataa catcctctaa aggattaatt
    68101 aatgctttta taggaattaa atcccccaaa atacccccga atataagacc ccatacagta
    68161 gttgaaactc cacagatacc aataagttta attaaatttc cttcaccttt ttgtatcttt
    68221 aatttatata caacaaatcc acaaactact gcaattatta acccatatgc ggcgtcactt
    68281 agcatcattc caaagaatat aacaaagaag aaagttaaaa ttgtatttgg gtcaatatct
    68341 tttgtacttg gatagctgta catgttagtt acactttcaa aaggtgttac taatttattg
    68401 ttttcaagca gaattgggaa gccttcttct ttacttcctt cttcagtctg aacacaacaa
    68461 tcaaactttt ctgtaatttc tttaattaat tcatctgccc ttttgcttgg taaccaacca
    68521 ttaagacaga atgttgtttt tgttttgaca agtctctcta taatcttttt ttggtctctt
    68581 tctatagtgt aaaaatcata taggttttca agcatgtgta tactatctgc atgtctttta
    68641 atttcctctg ttttgtcctt agaaacgttt tcctgtctaa ttatcatttc attgtatttc
    68701 ttgatagctt gtaacggtgt accttcttca tttggtaatg aaaccactga aaaattaaat
    68761 tcttttaaaa cttctaaaac atcatcaaaa gtttctttta aagtaattaa ataaacatag
    68821 ttcattaact tgtcagaatt gacaatccca ataacacttt ctggtatttc atcttctaat
    68881 tttactctta aagcatcaat gtttgcgctt atgggcacag ttccaagtat agtttttgta
    68941 tacttagttt ccatattttc aataggaata tcaaagttca cccatggttc taacatactt
    69001 ttattgttgt taagtaagtt tatgttagac cttattgtac ctatctcctt gtgcaaattg
    69061 tttaactcca gagcttcagc ataaacttgc ccttcttttt cactatcaat tttgttaaac
    69121 tctctttttg gtgcaagtag ggattttttt tgtttcacta gtgaagaaac aatattaatt
    69181 gcttggttta catgagacat tttctgctct agcattataa cttcagattc ttcactatct
    69241 tttacaagat aattttttaa ttcctcctcc tcagtaagaa aggcactatc atcaatctga
    69301 acaaacccac ggttcataag tagctttaaa atctggcttt tttgagcttc taagccaaca
    69361 atagatattt tgttcatatt aactattgcc atattatctc actacctttc caataaccgc
    69421 ttcaatagcc ttactttttc tttcttcagc agttttttca attttcagac attcactttt
    69481 agcattagct aagattttat caacctctgc tctactgtcg gtgactgcct tctcaataag
    69541 agtttcttcc ataagctttg cttgtttttt tacatcagca aatatgcttt cacatttgtt
    69601 tacagcatca gctctgatag actctgcatc agtaacagct tttactttga tactgtctgc
    69661 tgtctgctct gcctcaacaa tgctttttat tatttcaaaa gccatccaaa tcacctctct
    69721 taccttttta ctatgtatat aaccaattag atttttttat tctaattaga ttactacctc
    69781 attgttaaag tataaacagc atttttatat aataattaat atttttcaac gtttatttct
    69841 taataaaaca tattttagaa tagtacttgc ctagatttac atcctttttt gacttacttt
    69901 tagactatga catgagtatg gtttttaaat accattattt tcaataatta taatttaaag
    69961 cgatatagtt tgtcaatagc gttattttgt tttaaaatta acgttatgtc gacattttaa
    70021 atttttattt tatttttttt ataattttaa tttaatttat tacatataaa agttttttat
    70081 attctttttc aacctctaac cattgaagtt tattgttttt tttgaatttt tagaaatatc
    70141 tcgcactatt ttatctaact tttataaatc atcaagctat atcgattttt gtcaccttat
    70201 ttttaatcta atttttttat atctagttag aaataaatca atatttttaa agattgataa
    70261 aacttacacc tagttctaat agttttattt taaggcaatg tattaatctt aagtagataa
    70321 tatcattagt tactctatat attcgacaac attataaaaa aatcctcgta ccaatcactc
    70381 caatcttcaa taggatatgc tgctcctcca tttacacttt tcagtagatt ggatgtatat
    70441 tcttctccca tagaaaaaag ttcccctact gtcatatcat aacctctaga tgtaacaacc
    70501 ttacaaaatg aatccataac atcacgttgt tctcttgttt ttataagttc ctttctaaat
    70561 tcatcatcat tcttagcttc ttctaaaatt ttagttaatt tttcattcat tatgtatttc
    70621 tccttttaag tagtctttct gtaaacttca ataagcttta tataaaaagg aagccatcct
    70681 aaataaacta ggatgacttc gcttaactgt tagcaacaca tttactagta taaaataatt
    70741 ggtgtacctg gttctatatt ttcatatatt ttctttgcct tagaaaaagg tgtatttaca
    70801 catccatgtg aacctgaaga cttatatata cttccaccaa aagaatttct ccaagtagca
    70861 tcatgaatgc ctatgttccc attaaatgga agccaataac ttacaggtga actgtaacct
    70921 tgaccagtta atgaaacatt tctagcctta taattaagag gatatatacc tgatggtgta
    70981 gcaaatcctc tagctaaatc acctgttaca acgtctgttg atacaagcat ttctccattt
    71041 ttaaagaacc acatatgttg gccagaaaga ctaatctcta catatgtatt tccaatatca
    71101 tctttattac gagatacagc tttttgtatg taaataggtt ctcttgtaac atttttacca
    71161 gcttttacaa catcaactaa tgcttcagct tctttctttt tatctatcaa ccaaccataa
    71221 attccacctg aaattgtaat atctttacct gtggcagttt taaatggtct tgagtcacca
    71281 aaagtactgt attttttact taaacctctt gtatattcta ccatagcatc attatcaaaa
    71341 gttatgtcat aattcttttc tgagtctact tttaaccatt tattaatttc agaaccatct
    71401 aaagtttcct tacggtcact aaaatcatat gtaacgacta caccaacata cttatctaat
    71461 gtcttaatag cttgtttcaa cttttctgaa tcctttgtgt tgtttggtgc ttcataaact
    71521 ttactttcat ccagagaaat agaagtattc ccagaattaa ttgagttttg tactaactta
    71581 taaaaatcat cttttttcac tttgtttcca agtacctctg gtactataac ataagcgttt
    71641 ttagtgctat catacttagg ataagcactc ttaggttcta caacattttt actatcaaaa
    71701 caagataaag cattaaacct tttttctagt aaatctttat tatatgaaag agttatcata
    71761 ttattatact ctttagattt aaatattcca ccaatccatc caatagcgct ctgactatct
    71821 tttatctttt gaactttatc atctggtgta aattttaaat caatatcttt tgcttttatt
    71881 tgttctttct tattgtttct ttcctctaag tttaaagtat aggaattagt actagatgct
    71941 aacaaatcat ttacttgctc aactgttttt cctgaagcct ttacgccatt aatagtcgtt
    72001 ccaaagtaaa aatgatttct aaaaaagatt gccattccta tataagctac aaacaaaaca
    72061 cctactacta tagctatctt aaattttaga tttttttgtc cactttcttg ttttacctct
    72121 tttccatcaa tcataattaa atccttcctt acattgtaat tacctatgta ccttattggt
    72181 ttttaaacaa aaccatgtat gccttatttt atatacccaa attactgtat cattatttat
    72241 atttttaaat atatagttat ttctataaaa ccattttatc ttttagataa aatgattatt
    72301 ataaatcccc cctttcaaaa tcccttaaac acaatctctg ctatattaat atattaccat
    72361 acttttaata atcgtgggac tatctatcta tttttgtaac actaaactac tattttaaaa
    72421 aagaaactaa ttttgtgtta gtttctttat cttaacttat ttttatattg aattttagct
    72481 taacataacg ttgttatata gattctattt aattatttta gtttctatat cttttccatc
    72541 tgcatattct ttaagtaatt ccttagcata tccaaaatat tcttcaatat cagattcttg
    72601 actaaaagaa aatatacaaa ttaatatttc atttgcatct tctgttatca ttgctctttc
    72661 agaatcacta gttggactcc caaatttacc cactgaatca gacaatatag gaagattttc
    72721 tatatttatt aattctttcc caataccctt atactgttct ccttcatctc ctacagtaaa
    72781 acatactggt gaatgtaatt tgcttacatt atatgtacct actggatata atgattttat
    72841 tgatattaaa ttgtttattt ctactatatt atttattgta taaagaccct tcccttgaat
    72901 aattcttcta accaatgctt ctgaagatgt tctatatcta cttggatttt ttccaagctc
    72961 tttataagca tttcttgcat ctttaatttt atctagtttc gtaatgtctt caacttttag
    73021 actttgattt atagtatcac aaaactcatt tatttcatta attaattttt ctgagctttt
    73081 atttactgct acttttgctt gaatgcaacc cagcttagca ttaggccatc tttccttaag
    73141 tttgtcatca atacttatat ctatcatact taaacaactc ctatacacta aatttttatt
    73201 aaagttttta tcatctatac attatagtac tattcttttg ttaataacat gtttattagc
    73261 aaaataaatt tatttttaat ataattttta taaaatacaa ttattttttg ctttatatta
    73321 gacaatacat tgataaaata aaaaaacact aattatttag caatgattta ttaaaatcaa
    73381 gcattcataa tagtgcttta tataaaaatc aaattttgtt ttaaagtaaa tctaaaaaat
    73441 tcttagctgg cattggtcgt gcaaaataaa atccttgaac taaatcacat ccaaattgtt
    73501 tcattaactc agcttgttct ttactctcaa caccttctat aattacaact aaatctagtg
    73561 attttgctag agacactatt gattttgcta tattgcgact tctctcatca tgttcaatgc
    73621 caccaagaaa agacttatct agcttcaata tatcaattgg catatctctt aaacaactaa
    73681 tagaagaata tcctgtacca aagtcatcca tagaaataga aaatccatac gtcctcaact
    73741 catttaaaac attctttaaa atatttaact cattaatagc cacagtttct gttatctcta
    73801 tttcaatgaa atctgaactt aaattataca tttttattgt tttattgata aattttacaa
    73861 tatctggttg atacaactcg accctagata aatttactga aactggaact atctttttac
    73921 cttgcttttt ccattcatat aaatcattgc aaaccctttc aaatacaaat ctcccaattt
    73981 ttaaaatcaa cttacttttc tctgctattg gaataaatac tgcgggactt ataaaaccat
    74041 gttctggatg attccatctt attagtgctt cactccctat catttctcca gttacaagtg
    74101 aaaacttagg ttgataatac acttcaaatt gattttttac caatgctatt tttatatcgt
    74161 ctaaaatcat tgattcctca ctaagcttat tcctaacatc ttcattataa atagcataat
    74221 ttatattttt acctttagca acagacctag ccatatttgc tttatttaca gccttttgaa
    74281 tatctacttc accttcttca acaaaataaa tacccacaca cagagaaatt tcaaagacta
    74341 tactcaaatt actttcaata ttacttcgta tattatcaag ttttcttata attttatttc
    74401 ttccattttt ataatcacag aaaattgcaa aataatcact tgaaagtcgt gcatatacct
    74461 caccttctgt taattcttct tttaaagctt ttgctattgt aattaataaa ttgtcaccaa
    74521 attcatatcc aaaagtatca ttaatcatct taaagttatt aatatcaaaa tatactataa
    74581 tataatttaa agatggttta tctaaaagat acttactaca ttctctataa aatttatttt
    74641 gatttcctat atatgtaact ttatcttcat aagccaaact taatatttct ttttcattag
    74701 atttttttat ataaattata taaaaaataa ttgcaacaaa tattaataca atagataaca
    74761 ctgcatatac agctctgttg attatttgtt ttgaattact aaatacaaca gtttctggaa
    74821 ttgaaaaaat taaattccag tcttttatat aattattttc actattccca ttatccatag
    74881 tggcataccc taaatatctt ctttcttcca acatatttaa tacagttgca cctgttttat
    74941 tttcttgcaa ttcttttttt aatctattta cttcttgaat atcattatcc tgttctaaca
    75001 atttataaat attttttgat aggctatccc cttgtggatg aaggataatt gtaccatcat
    75061 tttttacaac ataagatata ctattatttt cataaaaaga tatattaata agtttcatca
    75121 gagtattgat attgtaagta caatataaaa ctccaactac tttatcatta tttaataatg
    75181 gtactgaaat agcaatcttc tttatagact tatttacttc atcaacatat ggacttgaaa
    75241 catacttctt acctttaatt gagtttttga aaaattctct atctttcact gaaaacttat
    75301 cacctttggt attttcagca ttaccattta tatcaactat tgccatagtg taaaattttt
    75361 gattttccat ttcatctaaa agatttttca ttttttcctc attaggtata tctggatttg
    75421 aagcataata gttagaaaaa atatttaaaa catctaaatc tttttcaatt tgtctttgtg
    75481 ctagttgaga gccttgtact gcaacttctt ttatatgtat ttttgcctct gacataagaa
    75541 gatgttttgt atcttctata tagatatacc ccattgtcaa aaataatgat gttaaaaaaa
    75601 gaattgtaat taatgtaaaa cttttatttc tccctgtcat tcgactcctc ccctaattag
    75661 tcaatacttc atatagataa tatatccttt ttataccaat tcatcattta tattgtatat
    75721 aactattctt aaatgttaca cataaaatca acataataac cataaaaaca ttcttttatt
    75781 attataataa cactatttaa ttgaatttta aattaaagaa taaaaactat ccattttctc
    75841 aaacaaaaaa actcttatac aataaaactt tgttttatgt ataagagttt ttattttatc
    75901 tattttatag caaacttatc ttccataata tgaatttaaa tacatatctt ttatttcatt
    75961 cataagtgga tatcttggat ttgctcctgt acattggtca tcaaatgctt gaattaccat
    76021 ttcatctatt gaatccataa acttagattc ttcaacgcca aactctttta tagatttagg
    76081 aataccaact ttaagtttta aatcttcaat agctaccaat aaactttgga atttctcttc
    76141 atcagaattt ccttttaatc ctaaaaatga agctatttca gcatatctct ttaatgcttc
    76201 tggatattta tattgagaga atgctcccat tttctttggt gcatctgaag aattaaattt
    76261 cataacttct gttatcaaaa gagcatttgc aacaccatgt ggtacatggt ggaaagcacc
    76321 taatttatga gccatagagt gacaaacacc caaaaatgca tttgcaaaag ccatacctgc
    76381 cattgtagaa gcatttgcca ttttttctct agcttctggg tcttttgcac cattatcata
    76441 tgcacgtgga agatattcaa atatactctt aatagcttgt aaagctaatc catttgtata
    76501 atcggttgca agcatagata catatgcttc taatgcatga gttaaagcat ctataccaga
    76561 agcagatgtt aagctttttg gcatattcat catcatatca gaatcaacta tagccatatt
    76621 tggcatcagt tcataatctg ctaatggata ttttactcct gtatcttggt cagttataac
    76681 agcaaatggt gttacttctg aaccagtacc tgctgatgtt ggtatagcta caaaattagc
    76741 tttttcaccc attttaggga atgtatatac cctttttctt atatccataa atctcatagc
    76801 taggtcttgg aaatctacat ctggatgctc atacaatgtc cacattatct ttcctgcatc
    76861 cattgcactt cctccaccta tagatattat tacatctgga ttaaattctc tcatagcttt
    76921 agcgcctatc ttagcacatt ccaaagttgg gtctggttct acttcaaaga atgtagtgta
    76981 cttaatattc atttcatcta ataaatcagt aactgcttta gtatatccat tattgtaaag
    77041 gaatgtatct gttacaataa aagctctctt cttattcatt acatctttaa gttcttttaa
    77101 tgctactcct aaacaacctt ttttgaaata aactttttct ggtgctctaa accaaagcat
    77161 attttctctc ctctcagcta ctgttttaat attaagtaaa tgcttaactc ctacattttc
    77221 agatactgaa tttccacccc aagacccaca tcctaaagta agagaaggag ctagtttaaa
    77281 attatataag tcccctatac caccttgaga agaaggagta ttaattaaaa ttctacaagt
    77341 tttcatggct gaagtaaact tatcaagttt ttctctttga tttacatcat caatatataa
    77401 tgaagatgta tgcccaaatc caccatcttc tactaatttt tctgcttttc taactgcatc
    77461 atcaaaatca cttgccttgt acattgcaag tactggtgaa agtttctcat gagcaaaagc
    77521 ttcttctatt tcaactgatt ctacttcacc tattaaaacc ttagtatcta ctgggacttc
    77581 aaagcctgca agttttgcta tagtacaagc tgtttgccca actattttag aatttaatcc
    77641 tccatttact aaaattatat ttcttatttt ttctgtttca tctttatcta ataaataagc
    77701 accacgctct ttaaattctt ttttgacttc attgtatata ttttctaata ctataaccga
    77761 ttgttcagaa gcacatatca taccattgtc aaaagtctta gatacaagaa ttgagtttac
    77821 agcagttttt atatctgcac tatcatcaat tattgctgga gtattacctg caccaactcc
    77881 aatagctggt tttccagatg aatatgctga tttaaccatt ccaggacctc ctgtagcaag
    77941 ggtcaaatcc acttctttca taacagttgt agttaattct aaagatggct catctatcca
    78001 tcctattata ccttcaggag ctccagctaa aacagcagcc tcaagaacaa cttttgcagc
    78061 ctctatagta gaattttttg ctcttggatg tggagagaaa attattccat ttctagtttt
    78121 taaagctaaa agtgctttaa agatagcagt agaagttgga ttagttgtag gtacaactgc
    78181 tgcaataaca cctattggtt cagcaatttt agtcatacca aatgcttcgt ctttctctat
    78241 aacaccacaa gttttagttt ctttatatgc attatatata tactctgagg cataatgatt
    78301 ctttataacc ttatcttcag caattcccat accagtttct ttttgtgcca ttatagctag
    78361 aggaactctt tgcttattag ctgccaaaga tgctgctaaa aaaattttat ctacctgctc
    78421 ttgactatat gtagcaaata ttttttgagc ttctctgatt tttgctagtt ttttaactaa
    78481 gctttcaacg ttatttacag tatctaaacc aactgacata acttcatttt cttttttatt
    78541 ttctattatt acttgttctt tatgagccat tttaacaacc tcctgagata gttttttatt
    78601 tattatgtta atttattaac attatagcat ttacttttcc tattttcaag ttattttttt
    78661 aacattttat tttttatcta atataacatc atttctacta ataatatcta gctttacaaa
    78721 tacttaattt aactagatat cactttattt tttacgcaaa tcactaatga aatcatctaa
    78781 aaacttaagg ataacgttat ttttttaacg tttatatttt tgtatttttt gcaaataaaa
    78841 ctttataaaa agaattttta atatgatact ctatcaagtt taaaaataaa aatccttgaa
    78901 aatgaaaatt aaaacttaat taacaagtta aagtaaatat agttaaatgt acaaacattt
    78961 acaacatata gtataattaa aaaaatatat attcatgatt tttatataat atgaaataaa
    79021 atatatttaa tattatatag ataaatttga agtttataag aaggaggata agcatggaaa
    79081 aattaaaaac aattagcgtt ttttctttga ttataagtgt aattttaacg attggaggta
    79141 ttggaatagt aacttattat gtagataatt tgtttattag aggactatca gtatttgttt
    79201 taattatgtc ctcttctttt gtatcaacaa cagttagatt gatatttgaa gagtcaaaac
    79261 gatataaatt ctaatttaaa aattggatta agtaaataat tttaatatag caaaaattac
    79321 ggagattagc tcaaaataga ctttttagtc catgaggcat ttttttgtat gaaattaaat
    79381 atattttcat catttcaaca agaaaaagag gcttctctct attttgagac agcctctttg
    79441 ctagtattgt atctaataca taatattata agaaccaatt ctattgatgt ggacttttta
    79501 taacaggctg tagctgtttg ttctctagag caagttctat agttggaatt attagctcag
    79561 tatgtgcaat catagaatta ggctttgctt tgcaattatc ttgaccaaaa ggtacaaaat
    79621 atatattttt agaattaagg agaatgccaa tatttttgaa attaaagctt agagcatcat
    79681 tcgttgatat tgatattact agtggtttat cattacgaag atgacctttt gctgccatta
    79741 atactggtga atctgtaata ccatttgcta attttgcagc agtatttcca gtacaaggag
    79801 ctattattat aatatcagca attcctttag gtccaaatgg ctctgcctct tcaatcgtaa
    79861 ctataggttt atttcctgta agttcatatg cttttttcat aaactcttca gaatttccaa
    79921 atctacaatc gatattttgt gatacatctg aaaatatagt gtgtacatta gctccttctt
    79981 taaccaaatt ctctaactct ataaatattt tatcataagt acaaaacgaa ccagtaaatc
    80041 ctactccaat tgtaagtcct tcaagtctca tttctaatcc cttctttcat ttataatatt
    80101 ttctatagcg ttaacaagaa tttcaccaga tgtctttggt gaatatttac caggaagccc
    80161 aaggcaaaga gtcgcattaa tccctgcttc tttaacaaca gaataatcta ctcctccagg
    80221 agaagaagct atatctataa tagttacttc ttgtgatact ttttctaacc tttctttcgt
    80281 taaaatacac tctggtatgg tgttaaaaat ataatcaaat tgtaaaagtt tttcatcaag
    80341 ttgacttaaa gaaatactgg aatatccaaa tgcattagcc gtacttcttg catcattatt
    80401 tcttgcgcca acacatacat ttgcatccaa agcgtataat ttttttgcaa gtatttgtgc
    80461 acatcttcca taacctaata ctaaacagtt actttgatgt atattgatta tacttctttt
    80521 aatagcttct gctatagccc cttcagctgt agcaactgca tttaaaatag caacatcatt
    80581 cattttcata aaatcataaa tctgaataga gtgttgctcg caaaatttac aaactttagt
    80641 tggtatgtta cctccaaata atatttgatt aggagataaa ttaattagca agttatcaat
    80701 agtagcatca agacaatcat ccgtattttc aatattaact tgattctttg taaatggaat
    80761 tggacataaa ataatggaac ttttggatag tgcttcagct agtgaagttg attttccaac
    80821 gattccattt ataatttcat ttgatatccc ataagtgact acagaatacc ctttattaat
    80881 tagttttttt accatgtaca cttgtcgcag gtctccccca ataacagtta tatcgtattg
    80941 atttgacata ttgtaagcct cctttactat atacaatatg tttttatcaa tacattggtt
    81001 cactaaaatt actaaatatt atacttataa catttttaat aatgctaatc tatctatctt
    81061 ttcagaagag gtatatggaa atgaatttaa aaagataatt ttctttggga tttcattttt
    81121 cattagatta tctttcattt taatcaacaa atctttcttc gtaattttgt ctatagttat
    81181 tacaaataat acaatttgat ttcctcttat agtgtctgag tacggcaata caattgcatc
    81241 ttcaatttga ggaatttttt taacttcatt ttcaatctta gtagaactaa ctttaaatcc
    81301 tccaatattt aaaatgtcat cacttcttcc ttcaaatatt aagtatccat cattatcata
    81361 atatccaata tcattgacag aataaggttt ggttgcatta tatactgcat attctgtatt
    81421 cacaaaaatt tttccttctc taatatatat atctattcct ggaaatggtc tgcctacact
    81481 tagaggtttt tcaattagtt catcatagca taaatatgta atataattta attcacttgc
    81541 cccatagtat aaaataattt cagactttgg catatatttt tttagatttc ttgcagtatc
    81601 ttcaaataat aattgagacc ctgtaaaaat acttacaact ttgagtactg gttcttttaa
    81661 gtgtttaacc aaaagttgaa gttttgtagg tataaggtat atgttagtta cattatattg
    81721 ttttattatc cttatccatg atttacaatt aagacctgaa cttattacaa tactacctcc
    81781 ttcatataat actgacatta tagaatttag attccctgta aaactaagtg ttccattaac
    81841 aaacaagatt gattccccag agatattaaa aataccattt tgtataggaa aaaatccagc
    81901 ccaactctca tatgttctat ataatacctt tggaacactt gtagaacctg aagataaagc
    81961 tcccatacaa atacttttat ctaaataatt tataaggttc ttatattgat acatatatat
    82021 attaaattta ggattaaaaa tagaaaaatt aacttttttt gctacttcat tattgttatc
    82081 atcatataaa tcaataacgt ccatagattc atcagatata atgattgaaa tattattttt
    82141 taataaaata tcatctaata cttttttaga aagattataa tgacaaataa taggaatatt
    82201 ttttgaataa ttaatagcaa aaaaactaat caactgaaac attatatttt tagaatatat
    82261 taaaattggg atattttcac ctaaagaaat ttgttttcct agttcctcac tataactcaa
    82321 tatattttca taagtatatt tttctccatc tataattaaa aaatttttat ttttatgcct
    82381 ctcttttttt attcttaaaa gttcataata gttcataatc tacacccttt caagcagtaa
    82441 agctgaacct agaccaccag ctgcagctat agagcaaatt ccatatctac ccttagtctt
    82501 ttctaatgct tttaaaagat gtaatgcaat aattgcacct gaagcaccat atggatgtcc
    82561 atacgctaaa gctccaccaa atatattata tctatctatt aactctggat attttctttg
    82621 aaacaacaca tctataactg caaatgcttc attaaattca acagcagata catctaaata
    82681 attaagactt tctatctcta aaagtttatc cattgcttgt atcgctgatg ttggacttaa
    82741 ggttgcatct gttcctattg tgcatgtatt aataattttt gctttaggct tcttttttac
    82801 atgttctaaa tacttcttag aacatattat aataaatgaa gctccatcat taataagaca
    82861 tgaatttgct gcatttgtaa tagtttcttt tcctaaaatt gatggcatcc tatctaataa
    82921 cctttgactc atcttatcac gtataccttc atcataggta ctattattta taggagatat
    82981 aatatcttca agtatttttt cctctcttgc ttcttttgct cttttatgac tttcctttac
    83041 ccaaaaatcc aagtctgctt tctcaatttg atataactct gctactcttt ccgcaccttc
    83101 gagcatacta ttttggctat tatcatcagg agaaaattga gcaactgtat aatttggatt
    83161 atttgtatta tatcgcttat cattcttatg atatgtgcgc attggttgta gagaactact
    83221 ttcaaaacca cctgcaataa ttaaatcaca ctgaccagat ttaacctttg aaaaagctat
    83281 gtctatactc atcatagcag aagcacactg catatccaca gtaaaagcag gtacttcatt
    83341 tgacactcct gctgttaaag tcattaatct agctatattc cctcctgtcc caactgcatt
    83401 tccacatata atctcatcaa ttttatcaat ttcatacttt ttaattaaat cttttaaaac
    83461 acttgctcct agtaattcag gttgaacaaa ttgaaaaatt ccatttttta gacctatatg
    83521 acttctcaat cctcctaata taaaaacttc cttcatacat tacacccttc cttatattat
    83581 agatttatca tagatttctt ctgagtacat tgttcagttt agtgcctaaa aaagatgcaa
    83641 taactgactt tattgtatct ccaattaaaa atggtactac tgctgcaaaa agtgctgctt
    83701 ctactgtcat ttgattaaaa tagcacataa atactgttcc cataaaatat ataataggca
    83761 ttccaacaaa aattgttatt agtatatatc tcttaatatc attatttcgt ccttttaata
    83821 aactaataat tagtgctgca aacaaaaacc caaaataaaa accacctgtt gggcttaata
    83881 actttccaat accagatgta cctccaccaa atactggaat cccaattaaa cctatcatta
    83941 tatatacacc aactgtacta aatgcttgtc ttggtgttaa aatcaaagct attaaattta
    84001 tcattattgt ttgtgctgtt actcctgctg gagtaaatgg caatggtata tatatgtaag
    84061 atgatataca caataatgct acacatattg acattttagt taaatcttga atatttactt
    84121 tagtattttt catttttata attcccttca tatgtcttat ttcatttagt ttatatgtac
    84181 atatacaaag cttctattaa agctttgttt tagtataaaa taaagacgtt tttttgtcaa
    84241 ctattataag catttaggtt tacatttaat ttataagtaa actttatact gttactttat
    84301 attttaatag tcatttataa aactttgctt aaaaacagct ctatttagac tatacttgta
    84361 aattataata tgatatattt ttatataaga ttttatttta tataaaaaat agtaacaaat
    84421 agtttataca caagatattt aaaaggaagt gatgatatga aagttaatga aaataatata
    84481 aataatatag atgaagagtt agatgaactt agtaggaaag tttacttaga gtcaccagat
    84541 ttttggataa gtatttctga caaaataata gataaagtat ttgatgaaat gttattattt
    84601 tttgcagtta aatataacta tttcaatata gtatgctttg ctattgaaaa caattatctg
    84661 gatttaaaca tgccttcaaa aaacaaaaaa tacactaata taatggagca tttgttagat
    84721 acatcaaaac agaatgaaga taaaaaaatt tataattatc ttctaagctt aaataaaggt
    84781 aataacctag atgaaagacc aattttagat gaattaaact gtaatattag tagtgatact
    84841 tttgaaaaaa aagatatata tcttccaaag tacttatgtc caagttgtaa ttctaatata
    84901 tttgatacag gttataaagt atcaaatgac ataacatata aattttcttc taaagaagct
    84961 gaacctattg aaatgtgtag tgaagtttct tctatcagat gttgtaattg tgatgaatta
    85021 ttagaagata ttacacttga taaactatat aacctatgca aaattcaaaa ctgtaataat
    85081 tgtggttcta atttaactaa ggtaggaatt attgcaaaga aaaaaatgaa ctttgatgag
    85141 aatactgaaa aatttaaaga tgtctcaaca tcttactgtt gtggaaattg tgactctgaa
    85201 ataaacttat ctcaaagaga acattttaag atttaaatat ttataggcta aagtaataag
    85261 attacattat tagatactgt ataagttttt taaatctgta aaaataaata cacttataag
    85321 aattaaaatt gctatgaaac tagttcttga tgaactaatt tcatggcaat tttctataat
    85381 ctaataatta ttaaatttta acaaaccttt attagcattc cataattatt taaaattctt
    85441 tcaaataccc tatagtttat aggtgaaagt atctttaata ttatatcaaa cttattatct
    85501 ttaaatagta aatttgttaa atctgaaata caccatacaa ttttattttc ctcttttgta
    85561 gctatatcaa ttctgattaa cttacatcta taataaatat ctttatcttc atatagtcta
    85621 ttttaaaaat tactcttaaa aaatcaaatg gcaaataaat taattatcct tttaatagaa
    85681 tgtaatcata ttatttacta tattccatta tgtactcttt aaatcctgaa tcttcattta
    85741 cttgttcttt tactatatta aaaccttttt tattataaaa cacaactgct tttttattat
    85801 ctttatatac tgctaagctt agacttttat attttttagt tgcataatct aaaagtttac
    85861 ctccgatacc tagattttgg tatttgggct ttataaataa agctcctata aagcttttat
    85921 ctattatgct tataaatcct tttatttcat ctccatcatc atatacaaat gtatctgata
    85981 taggtatata ttcgttttta acagtattat agttattttg ccagtattct ttacttataa
    86041 agtcatgtgc tttgattgta cttttttccc atatttccat gattttattt atatctttat
    86101 tgtttaattt ctttatcata aattttattt cacctcattt ttgtattgat tttataatgt
    86161 ttataggtaa gtttatttta tttagatatg atttagttaa tataaggtgg atgttttagt
    86221 atatgctatt gttgattcta caattttata tactgcttta ttaatataaa ataagtttct
    86281 aaatactcgt tgatattgct aatattctac ttatctacca cttagttaat ataaaacaat
    86341 gatactgtaa tatctaaaga tgttacattg gcaaatttac ataccactta gttaatataa
    86401 aaccatcttc agtatcatat gctgaaatat tatcaagatt tacataccac ttagttaata
    86461 taaaacggca atcatgtcaa gtacttctaa tataaaaaag ttctatttac ataccactta
    86521 gttaatataa aaccttacat ggaaaacgaa acatatttaa tttgttctga atttacatac
    86581 cacttagtta atataaaaca aatgaagcat tgagtttaaa tagcgatatt agaaaattta
    86641 cataccactt agttaatata aaacttcaat gaactagggt ttaaaataca ttctagcccg
    86701 aatttacata ccacttagtt aatataaaac tttaaaattc cggacaaaca acgctaaatc
    86761 aaaagaattt acataccact tagttaatat aaaactaata gaattatagc atcaactaat
    86821 cgtaaaatat ttatttacat accacttagt taatataaaa cttgcggtaa gactgtttgt
    86881 tacagggatg gcagagtcat ttacatacca cttagttaat ataaaactca actctccttg
    86941 atagatttag cctatcttgc gatatttaca taccacttag ttaatataaa acgaacaaat
    87001 ttaatggaag caataaaaag taatgacgat ttacatacca cttagttaat ataaaacgga
    87061 ggaactaaat ttagcttact ttgataaaga aagatttaca taccacttag ttaatataaa
    87121 actcaatatc ttttcttatt agtttcgcaa attcttcata tttacatacc acttagttaa
    87181 tataaaacga aggcaaaaac taatgactaa taaagagaaa ataaaattta cataccactt
    87241 agttaatata aaacatattt aaagcaagta cttttttaag aaaacttaat ttacatacca
    87301 cttagttaat ataaaacatg gctaagagat acagataaaa atataaatga atggtattta
    87361 cataccactt agttaatata aaactattac gagaaaaatt taaaaacgac taaaatccat
    87421 atttacatac cacttagtta atataaaact ccatttattt tatatattaa aattatagca
    87481 ttcgaattta cataccactt agttaatata aaaccttttg ttttaggatg attatataat
    87541 attacaaatt tatttacata ccacttagtt aatataaaac ttggacttat tttattgact
    87601 tataaattat ctaatttatt tacataccac ttagttaata taaaacaagc agaaataata
    87661 ggactaatat ctatatcaac caaatttaca taccacttag ttaatataaa acgatagaag
    87721 aaaataatat aaaagttacc ctaaattaat ttacatacca cttagttaat ataaaactta
    87781 gaagatatag aagttcttgt agatactgtt gagatttaca taccacttag ttaatataaa
    87841 actaaattta aaataaatta ttaaatatcc gaaaaaatta tttacatacc acttagttaa
    87901 tataaaaccc caaaataggt atatttgaat acattgaaaa cacttcaatc aagcaattat
    87961 aattcaataa aaacatcaaa atttgcagtg agcgagcagt agtgcaattg ataacaatta
    88021 tcatacacct tcaatccctt atattccaac tgttaacacc tattttagca taaatatcgc
    88081 tcactgcaaa cctatataaa catttcatca gaatacttat caatcccata acatttcttt
    88141 ttaattgaat taggattttt tatctcataa acatagattg aatcctcgct attatcaata
    88201 atattttcta tttcagaaat acatttatgt aactttcctt cagtaatatt gccttcaaaa
    88261 acagaatttt gcgtccaagt caaatatttt ctaagtatcc ttctaattct atttaacgac
    88321 cttgcttcaa caatatcata agtaacaata acaaacatac ttaccaccac acctttaaaa
    88381 ctttgtacct ttcatcattt ataaaatgtt taattaattt ataacactct aaccttataa
    88441 acattctata tgaaactttt ctatttagat ttctatgttt tatagttgtc tgcatcttat
    88501 tttcaaattc ttgcaaaaat ttcttctttc ctttttcact taaataacaa attttgtctt
    88561 gatattcaaa atcattctta ttaattcttt tattattaat caggctaaaa attattgtgt
    88621 caattataat tggcttaaaa atttctgcaa tatctaaact taaagaaaat ctctttgttg
    88681 atggttcatg taaaaagctt attgtagggt caagttgtgt cttatatatc tcacttaaaa
    88741 cattcgtata cattatgcta tttccaaaag acataagagc atttactggg tctttgggag
    88801 gtcttttttc tcttttataa aattcaaaat catcttttaa tatttgatta aatgatttat
    88861 agtatgtttt tcttattctg ccttctttac ccataagttc tgatatttct ttgacatcat
    88921 tcaaatcatt tagttcatcc tttatagtat caattaaact ttcatcaact ttgtaatatc
    88981 tcatatttct taaaatatgg tatgatgcac tttccacaaa ggattttgct aagtataatc
    89041 tttcattttt atctaaatag caggctgatt gacatactaa actgaatcct gatacatttt
    89101 tcttccttgg ataatatgta cctgaataat atccatagta attgtagaaa tgaagcatca
    89161 ccccatattt gcttatgtaa tttataagtt ttgtatttaa atctacttct ccatatatat
    89221 gaatatcatc aacttgttct actggtaata tttttttctc accttctaaa ttgtaatagt
    89281 aaatcgtatt ttctttcctt tttatatccc cattacttat aatataatag tctttataca
    89341 ttgttactcc tccttcacaa aacaaaattc ataataagca cattttgtac aataatgttt
    89401 tttctcaatt ttgggaggag ataactgcat atttatttca tttatattta taagtgtgtt
    89461 ttcaataatt ctttcttttt cttctgtcaa tatcaattct tcttgtttct tttccttaac
    89521 ataatttata gtaccttttt tctctatacc catactattc tttaaatagt ataagtaata
    89581 gtataactgc atttcatctg cttctttcat ctttgaactt atttttactt cttttacata
    89641 ctcatccttt attatatcta gcttcaagat atcatcaatc aatatttctt tatttttcat
    89701 tcttttatat gaatcttcat gtactatctt cccagacaat actctactac tattttgttc
    89761 catggttatt cctttagaaa atagccatag ttttctttta catacataat aataatttat
    89821 ttttacacct tgaactttta atacttctaa atctattggc acaaaatcac cttctttagt
    89881 aaattttagc cacattgtta atataaaaat caaataaatt ggtctatttc attacttata
    89941 agcacacctt taccaaatat ctgttttgta tgcttatttt cgtatatatc atatttatat
    90001 aaaagtattt ttaaatcttc aagacctttc acctgtatgt caattacatt ttgtttagct
    90061 ttatatattg gtaaatttac agttttttta attatctctc ttcttgcttt ttttctctta
    90121 gactttattt tatttatcaa ttgtctatca tcattactat atgcatttat aagctcttgt
    90181 cccaactctt cataatcttt gattaaagtt tcttcaattt tattatatat atcctctgga
    90241 attactgtat atccttcaat atttctaagt atattttgtg catctttaga acctaaacta
    90301 tatggcgtta tagtatctaa aatatttaaa gcactggtaa atctcttttc aaaagctgta
    90361 ccttctagac tttctttaga gtatagtatc ttaaccattt ctaccttata tttttctttc
    90421 atcttcacac attcttttcc atttataaaa gttttcagta gctcaagtcc tttttctaca
    90481 atatccttat cataaatact acctattcct gtagcttttt ctgtatatat aaatatattt
    90541 gggctatttt cttcatactc acgacttcta taacatctac caaatcgttg aaatagactg
    90601 tcaagtgttg aattttctgt atgaagctca tcaaaatcaa tatcaagaga tgcctctact
    90661 aattgtgttg taatccaaat tccatttcta tcactattgg caaattcttt tatatatttt
    90721 tctaattttg ctctatcttc ttgtatatac atagaatgta aaagatttaa gttgacatct
    90781 attccttttg gtttaactat ttcttctatt aactcatatt tttctacagc acttttaact
    90841 gtatttacta ttacaagaac ttttttattc attccacttt gtattatttt acctaagttt
    90901 tcatctattg aattttctac aatagaaaca caatgtctta ttttttctgt attacatgtc
    90961 aattcagcta agttactatt cattacacct ctttttttta attcatctat atatatggtt
    91021 ggcatagtag ctgtcattat cataaatctg ccacctatct tatgtatcat ttctatacct
    91081 tttaccaata cagctgctat ttctggtgaa tatgcttgta tctcatctat tactactttt
    91141 gaatatgcta atgttgagta cactttttca taccctctat acaaaaaagg aaatttaaat
    91201 atttggtcta ttgtagaaaa tgtcagtttg caagataata actttgctaa atctacaatc
    91261 tcacttgaat tttcttgatt actttcttct agataatcta ttgctgttga atgtaacaaa
    91321 cctaagaatg tatcatttga ttctccaaca ccaactatat tttttgctct atcaaataat
    91381 gcatttatac ttactcttaa tggaagtgta aaaaatgcct tgtctttatc tatccaaatt
    91441 aaggcagttt ctgtttttcc cattcctgta gatgcaatca gtattatatt cttatttcta
    91501 ttagatttag caaatgattg agcctctctc aaactaccaa actctttcat taaataattt
    91561 tctgtctgtt ctcctatatt tataacatta ttgcattcca caacttcatg agcagaagca
    91621 ctatggtcta gtctatgtag tattcctttt aacataatat ataaattata gtacttgtga
    91681 tttttatcta ttcttttttc tacactttgt agatatactt tactcaattt ttctgttttt
    91741 attggatatc taactttaaa ttcatgctgt agttcataaa ctttatttat taaatcttca
    91801 tctaatattt tttgtattaa atttttaaaa tctttatcta taaagatatc tctttcatga
    91861 tgatatacaa taacttgatt taatactgct ctaagttctt tatttttttt cctgtctata
    91921 taactataat caataaatgc aggagaaaga taattatggc ctacattatt ttctaaataa
    91981 gttactattt taggttcatt tattttagta tccattctgc tttttattaa ctcttgaaac
    92041 ggtgaaaatg cttttccaat atcatgaaat tctataacaa agtcaagtaa ttgccaaaat
    92101 atctcctctt ctagaaaatc taagctattt atattttttc cataactttc tcttaataca
    92161 ttcatttgtt ttaaaagttc atcagtatgt tctctaagtg tttccactgg attagattta
    92221 gcatataaca taatctccct cctaatttat attattaaaa tataataaat ctccttcatt
    92281 atctaataat atatctccaa ttgatatagt atttccatcc tcaacataat aactatctac
    92341 cttattccaa accctttttt tatcttccac agcattatta tcatagtaat tattgagtct
    92401 gtaacttata ccatctatat ctgtatcttg taaacttgtt tttggtatat atataggcat
    92461 tcttatatta cattctgata acttataatt ttcataatca tctaattgta tatcctcatc
    92521 tacttcaaat ttattgactt ctacaaatct aatatcatta attcttacta aatcttcttt
    92581 tctacctaat gataagtgct cgtcataatt taataaacta tcatatattt cttccaataa
    92641 atcaaaatcc ccacctatat gaattatcaa atttacattc aatagcatat gactattcat
    92701 tggcatagat gtaatactat cttttttata aaaatatgtt gtctggtaat tattaaatat
    92761 actttcatat gttccctgta cacttatatt aaatggtata tattctgtag catttaatat
    92821 tttgtgaatt aatccattta ttgtagaata tggaggcagt ggatatgtct ctgtaatctt
    92881 catagcaaat ggttttttgt agcatgcagt ttcttgaaat aaatctaatt tcaaaacctt
    92941 catattaatt caccccataa tattccttta cttctttaac tagttgtcca aaaaatttat
    93001 ctacacttaa aaaattatct tcaaacaatc ccttaaattc ttctttattt ataaataccc
    93061 catctaccat tccaacatag gtaaattctt ttaaatcttt tcctaaaaaa gtaccttgaa
    93121 ttacttcttc tatagcttgc ttatttattt taaatccatt tttatctcct tttaatttaa
    93181 ttctacccaa gaaaaatgga tttgctattt catatactcc tcctactaca aatagaggag
    93241 ataaattttc ttgtctacct ctaatatttc tattcaatac ttttattatt tctaaaaatt
    93301 ctactactct tctacatttc tctttattat caagttctat atctccatcc ttacctattt
    93361 tagataaatc tatagtcact gtatatgtat aataacttaa atgttgctct atgttagcaa
    93421 gattaggatg ttctcctatt ctatctgcta atcctttatt atttaaaaag tccatgtcac
    93481 ttctatatgg ctcaagggaa attgcattac ttaatcttac agtagcttct ctagtcaaag
    93541 aacctccttt tttatctttc tcatcttttt tatttgtttt catatatcca aataaatcca
    93601 tttcttctga ttctcttata cttatattgt ctttaaattg aatagtgcct ttttctttat
    93661 cgacaacctg taaattccaa ttaaacaatt ctgctgctaa tcgtactatg tcatatctta
    93721 aacactggcg agatgcaaat gtatatatat ttccatcatc tctacttaat ttttttaatt
    93781 ctgatatatt acctatccct tccccatagt ttaaactttg agcctgtgct attactgtaa
    93841 atgttaaccc tcttttcatc ttatttttcc tccttttcgt ttggtagttt atcttttcct
    93901 tcatattttc cagaaattaa tcctgttaca aatgcatacc ctacagattc aaaatctaaa
    93961 tcttcttcaa caaatatctg taaaatttct tctggtggtg ttttttcact tggtgaaaaa
    94021 attcttaaaa ttgtttgcat aaaatcattt ttattaccaa ccttaattaa atttaaaatt
    94081 ttatatgtta ttccttctat tttattttta gcattcttat caatataata atcatgtatt
    94141 tcacaacctg actcataaat ctttctcaac tttttatagt ccattttata cactcctctc
    94201 ttatagttat ttaatattgt tcttaattga acaacattga aacaagataa ccctgatatg
    94261 tttgatttat tattgctttc taaattactc ttaactatat tccttaaagt gttattaatt
    94321 aaatgtttta agtctttact ttttaaaatt aaatctaaca catttgattt aagtttataa
    94381 tcatatatac tttgtatttt tttattttct tttacaaaaa actttgctaa ataagttgga
    94441 atattaaaat aatttatttt acatttttta gaatctatac ttgctttaaa ttccacaaaa
    94501 agtatattac gaagttgcca ttcacttttt aatgtatttt cttctactat actttttata
    94561 agctgattaa aaggattttc atctttggaa tctgaatact cacttttttg agcttttaaa
    94621 ctattatttc tttcaaaaag ctcatttata caagtatcca tgttaacaaa taaataaaac
    94681 tcattttctt cattaattaa ataattcttt cttgtataag tagcccctgc tggagtacag
    94741 aacaatatta gcttacaaat atcacatatt gatggtacat acgcctgatt ccaaaacata
    94801 ttcctagcat tattggtgct tactccaagt ggagcaaaat tactttctga gtattcatct
    94861 aatattccct tatataaacc acacatttca catacttcta aactatccat atactttttt
    94921 atatcttcta tgcttttatt tttctttata aagtttttat ttatttcctt cataattttt
    94981 tctatagtat ttatactaga cttactaact tttttttcat ttatatcctt agctatacta
    95041 tttaatctat catttaaata gtttttcaac ttgtcatagt cattctcttc taataaatct
    95101 tctaactctc caaaatatat aatttgtctt aaataatcat taaacattac ctgttttaat
    95161 ccatctaaat ctaatttcgc cttagcaaca ttaaaaaaac taacttgtcc aaaataatta
    95221 tcttgaacta catatttata aagatttgct gtaagcctgt catttattga ttttatttta
    95281 aatatatcta tagtctcatc tactaaagct tctaaactat caaattcatc ataacttttt
    95341 atcttagaca tactatctag cttctctttt atcatgttaa atttttcttc atcaaatttt
    95401 ttaatcttat cattttgttg tttcacacta tctttaattt tcttaattcc atctttgatt
    95461 ctatcaggct tagatttaat aaaatttata ctgtaatcaa tatttttttt aattcttttt
    95521 gatacatcat attcatccat aaagtaatta aaataatact catgaaagtt ttcaagaaat
    95581 aagctatcaa attcgatata atcttccata ataaatattt cagcttgttt atctgctttc
    95641 tttattatat ttaaaaatcc aactataccc atattaaaaa accaatctcc tctataaact
    95701 cttaacttca tttatctcac ctccattcta aaatatctac atctccaaat ccctgagcac
    95761 gtctaaaacc aattcctaga ttgtagataa gatttaaatc atcaatatca cctttcaata
    95821 taaatttacc tttgtaacca ttaatatatt gatactcttt acctgttatt tttttaaatt
    95881 ctcttaaact ctctttaact actacctttt tgagacctat attttcaaat tctaactttc
    95941 tttttaatcc attcccccta taatttttaa ccacttcatt agttatatag tttagttctt
    96001 ctatgtatct atcatcagtt atctccaaga attttccttc tttagacttt acacagattg
    96061 gagacaatgc attaaatagt accctttctt ctgttacctt cttttctctt gataaatcga
    96121 ttctaattct tgtaagttcg tagtctttat ataaacattt tttagaagtc attaacccat
    96181 tgtatatatg aaaacccaat tctaaatctg gagtacttat atttaatatt actttatctt
    96241 ctataataaa attgtcacct tcaatactat acttttttat ataaaccgaa aatgtaaaat
    96301 ttttagtttt tttattattc ttttctttat aatagtacat gtttttatag taatcttcat
    96361 tagattttct tattgcttct tttataatac tcataaagag cgaattataa gatattggta
    96421 tacaacctgt actaaattca attttcattt tcataatatc acctctctca attaatatat
    96481 taacactaga ccgtgaagta tattggtcca agtataaatt atttgaaaaa atcagtaaat
    96541 ttttttcatt ttttcaatct ctaacaatat atcatttcta agtctatctg gttctacaac
    96601 ctcaacataa gctcccatac ttaaaatcca actttttatc tcctcataac ctctcatttt
    96661 agctttaaac attatagatt tatcatcata ttctatgatt tgttgattat taacccaaac
    96721 tttctccttt ataattgttg aaaatggatg actaattttt ataacaacat taatttcttc
    96781 tcccttataa attcctatac tatttttact atattcatcc caactaaaac ttttatctac
    96841 attatatttt tcttctaaaa ccttataatc tttaatccta cataatttaa agtctataaa
    96901 cttaaatctt ttttcacaaa aagctaccat ataagtatct gatttataat taaataaacc
    96961 atatggatga acaattcttt cactatttcc tgaatttaat gaataatatt ctatccaaaa
    97021 tttgtgtttt gtggtatatg ctctaattat ttcattacac ttattttttt cagactcata
    97081 atcacaatta cgttgtgctt gaactgtaaa ataatccata tatgtatcgc ttttttctcc
    97141 tgtatttaat actgctttta ttttttctac aatattatta aattcatttt tgtaaatatc
    97201 attattatac tctaactgtg aatttatcat atctagaatt gaaacttcac tatctaataa
    97261 tttaattaat gagatgctat tacatttatc tatttcataa ccaccataaa tcccaggtgt
    97321 tgaatttata aatataccag cttgctctaa atacatcttg taacttttta tttgcctttc
    97381 acttacttcc aactcttctg ataattcttt gcatttcatt ttgcctctgc tttgaattaa
    97441 tatcatcatt ctaagtgtat tagctaattt actaatgagt aaccccccct aataacatta
    97501 attgatattt ttattattta tttctacaca tatgtacata taacctcttt atattttata
    97561 taagtagaat ttttttataa ttttgacatt taccatatta tattttatat ttgtacaaaa
    97621 ttttaatagt taatacaata aaaaatatta ctgaaaaaat aaacatctat aattccagta
    97681 atattaatta attctaaacc ctttttatta tcatttaata atagtaacta aaaattgact
    97741 aaatttaacc ttatctcttt taaataatta tttcttacaa ttaaaaaata aactatttga
    97801 accaagaaca agcttcccat taccaaaaca gctgatgatg ctacttctat atcaaaagaa
    97861 tttttcagtg cagtaagtgc aaatattgaa tgtataacag ccactacata aggaaacaaa
    97921 aatactattc caatctcaat tgttgaagct tttttaatct cattatatgt catacccaat
    97981 ttatttaact gttcatactt tttcttatca acttggcaat ccatataaaa tttattatat
    98041 aaaaaactac ttgtagtaac aaagaaaatt aaacctataa atattgctaa aaatataaat
    98101 gtagaataca ttaatttccc agttcctatc attaattctt tagagaaaaa caaatatggt
    98161 tgcatccctg actcattatt aaatttattt tcaaattctc tgcatatctc tatagtttta
    98221 cttgaatcct ctacttcaaa tgcagtaaat ctatccacta taaattttga ttctatacta
    98281 tcataaaaat tatcctttac cacatacata tttttgtaat acgctggcat aacacattct
    98341 tccacttgtt ttgccacctt taaacctcta ttccctacaa taatattttc tttgacgttc
    98401 ttatttcctg gtaaacttga tgataataat gatatacatt cattatcttc aaaacttata
    98461 ggcttaaccc ctatagtttc tgtaatttct aagtacttag attctttcat aattctgaca
    98521 ttaaaatcac ttttcttggg aaatacagtt ttaaattcac cattaatcct tgtatagtct
    98581 acattctctt tttttagatt attttctata aacatcattc tttccttgtc tttttctttg
    98641 ctatcaggct ttttagggtc attatgcaat gtcattgttg aataatatat tgtgttagga
    98701 tatattaaat taatttgacg ctctacatct ttccaaaagg aataaactgt acctatagca
    98761 gtaaatgcca ctgcagaagt tatagttatc aagaaaaata ttctagcatt atcctttacc
    98821 ttataaatca agttcgaaat ccaaagcata tttgtatttt ttctataaaa tctcttgttt
    98881 aattttagct tcttcataaa aaatacacta aattgagaaa agaacaagta agttgctact
    98941 atagtaaggg atgtaactgg aactaagcgc agatatgttg tatattggtc ggttgaggta
    99001 atagcattat aatacgctat tataaacaaa caaatactta atatagcaag cattagtgat
    99061 gttttaggct ctggttttgg agtttttgta cctttaagta acttcaacac ctgattttct
    99121 ttaactataa aagaagtaaa tattgatgtt aatacagcta aaatcataaa atagattaaa
    99181 gtagacaata tcgcattaaa tggtatatag aattttaatg gtgataattc taaaaaagta
    99241 gacataacca ctaaaaatat ctttgcaaag attaagccta ttattattcc aattacagaa
    99301 gatactatat ttattatcat attttctata aagattaatt tcattacttg gcgctttgat
    99361 atacctgtaa tataaagtat tccaaattct ttatatctac ttttaagaaa cacactaact
    99421 gaataaaaca caaagaagaa taagaataga tatgcaatta tcttactcat cttgagacct
    99481 tcttttaaat aatcaggaaa ttgagataca tctaaatctg gatgacttgt aaacataata
    99541 aaagaaaata gcagtgaaga tgatataaca atacttgcta agtatcctaa atacgcttta
    99601 atatttcttg aaatattgtt aatagcaaac tgttttatat tcattagtta tcgcctccca
    99661 ataatgtaag tacatccatt atctcttgat aaaactgctc tctactacta cccttatata
    99721 tttcattata tatagaccca tcttttatga ataagattct actacagtag ctcgctgcta
    99781 atgggtcatg agttaccatc atagtagtaa ctttattttc tttatttatc ttttgaaata
    99841 gctccattac aacctttgat gactttgaat ctaaattacc tgttggttca tctgctaaaa
    99901 gtattgatgg attgttaatc aatgctctag caatagcagt cctctgagct tgaccacctg
    99961 atacttcaaa agttcttttt cctaataaat cttttatacc taatattgta gatacttcat
   100021 tcaatctctc atcttgctct tttacactga ccttatctaa tgtcaatggc aatactatat
   100081 tttctcctat agttaatgta tccaataaat taaaatcctg aaatacaaaa cctaactctc
   100141 ttcttctaaa taatgcaagt tcctcacctc ttaacaataa aggattcttg ccctttaatt
   100201 ccatagttcc tgtagttggc ttgtcaatag tagaaatcat atttaaaaga gtagtttttc
   100261 cactaccaga tggacccata attcctacaa attctccatc ttctatacta aaatttatgt
   100321 catttaatgc gttgaaaatt atttttttac catatacttt acttaaatta tttacagtta
   100381 aaattttcat tatttaacta tccttcctaa tttaattttt gaaataacat atatataatt
   100441 gttaattata atttatctta gtttaatttt tatagataat aaatctattt tttctataca
   100501 ctaattatgt tagtaaaagc taatactgca agtactacac ccatgattat tctgtataca
   100561 gcaaacactc tcattggttt tttctttaaa aaattcacga atttttccat aactattatt
   100621 gatacaataa aagctactat aaacccaact accaaagcaa tccacaatgt tggtgtcatt
   100681 attgaataat caaattcaaa taaatctttt cctgaagaag ccaccatagc tggtactgct
   100741 aaaaagaaag aaaactcagc tgctgtagga gaattaagtc ctgctatcca tccacccata
   100801 atagtagatg cactccttga catacctggc catgcagaca aaacttgtaa tgtcccaacc
   100861 tttaaagctt gtattggagt aattttatct atattatctg tggaatgatt cttttttcta
   100921 aacaaagttt ctactactaa taataaaatc ccacccacta taaatcctat aattacagat
   100981 tgtaaattaa acaatgattt tatattatcg taaaatagaa ctcctataat cgcaaatggt
   101041 atacaaccta taattacatt cattccaaat ctaaaaccaa tctttccttc ttttccacca
   101101 gtaaatataa atttaaaaaa ttctataacg ctatctttta tctttttcca ataaagtact
   101161 actactgcta atatagcccc aagttgtatt acaacctcaa acatttcagc aaattgcccc
   101221 ttaaaatcta ttaaattacc aaccaaaatc atatgacctg tagatgaaac tggaataaat
   101281 tctgtaagcc cctctactat agctattatg actgatttca atataaaaat aacatctaaa
   101341 ctcatcaata aacatccttc cttttttaca aaatttcttt ttttatgtta tttctcttat
   101401 gttatttctt atattaattg taatttagat tagaaaattt aactatctgc aaacattaca
   101461 caaaccttac atctatgtaa ggtttgcaaa taaactctct taaattttga ttatttaact
   101521 atgaatattt catttaataa attgtataat aaaaaagtac aattaactaa aaaccctatt
   101581 gtaacagata atttacatct ttatcaaact atttacacct ttattaaagt agattgaaac
   101641 ttctgtacct tttcctactt ctgattttat acttacttta tgacctaaat catcacatac
   101701 cttttttact agataaagac ccatacctgt agattctcca aacttacgac cattttctcc
   101761 tgtaaaaaat ggggcaaata ccctttttaa atctttagaa acaattccaa ttccttcatc
   101821 tattatactt aaaattacat atttattatt ttcttcagat tttatagtta ggtagttact
   101881 ataatcttta gaatatttca ctccatttgt aattaattga cctattataa atttcatcca
   101941 ttttacatct gtataaacat aagtaaactt gtctacttga atcttaggaa tcattccact
   102001 ttttataaat aacctttttt cttcatttac aatactagat acaatttcat ttaatttggc
   102061 tttttcaact ataaagtctt tctgaaaatt atctgccctt gcaaaatgca tagccatatc
   102121 taacccttta ttcaatctat ctatttcttt tcttatattt tcagttactt cttctccctc
   102181 ataatcttgg agctgaaggc ttataactga tattggtgtt ttcatctgat gaatccattg
   102241 gttgatgaaa gttaaatgtt cactatgtat ctttttatgc tcttgtatca ttgattgata
   102301 caatttatgt tgttgtttta aaataactga tatatttctc cccaagaatg agcttcctaa
   102361 atacaaaaat gactcctcca aagaatgtac tcctttttca aacagattat atacttctct
   102421 atttttataa tacttatata ttaaaaaaca taacaatata aaagaactaa ataaaagaat
   102481 atataaactc tctccaaaac taataaactt cataagatta cagtaaataa ttgtcataac
   102541 tatgcctata taatatataa aaatataacc tttataatct tttaaaaata acttcatact
   102601 ttctccttac caattcttat ttaatttata tcctaaccct cggacagtct gaacagcatt
   102661 atctatacct aattcctcaa atcttttcct tatcctgcta acatttacat ttaaagtatt
   102721 ttcctctaca aactcaatat catcccatat cttttctaaa agataatctc tacttactac
   102781 ttttgggtat ctcttgataa gacattcaat cagtatacct tcttttttag ttataattag
   102841 attctcacca tttaattcta gttctaacct ttctggataa aattttaatc catctagctc
   102901 cactattctt tcgtctattt taggtgaata ttcaccatat acccttctta tatgactctt
   102961 tatttttgcc attactacat catagtaaaa aggttttgtt atataatcat ctgctccact
   103021 ttctaaagct ctaatttggt ctacattacc atctctagct gatataaaaa ttataggtaa
   103081 attcgactgt tgcctaatac atctacacca gtagaaacca tcaaatttag gtaaatttac
   103141 atctaataga actaagtgtg gcttaaaact ttcaaatgta atcattatat catcaaagtt
   103201 ctcttcaaca atcacttcaa atccatattt ctcaatataa tctttaagta atgtacttat
   103261 tgatatgtca tcttccacaa tatatacttt ataactcata taattcctcc taatatacct
   103321 atttactcat catataacag tccaatttta atatattata atctttttac aatatataaa
   103381 tttaatcata ttactaactt cacaattact gacttcataa gtataaccat attattagac
   103441 atcttaataa aactctataa aaaagtatct ttttatgatt aattaatcat tattatcaac
   103501 taatcattct aaaataaatt gaaattacta attcaaaata gaaaaagtta ccttaataag
   103561 gtaacttaaa cttttattat atttcttact tagtattatt ttatcatagt ttctacttag
   103621 cattatagat taattctttt atgttcactt ttttctcttg taacttattt tttattaaga
   103681 agtcttgtgt atcttcaagc gaagatatgt ctttatctgt tatatctaaa ctaaaatcat
   103741 accaagcata taattcttta gtttcttcaa gacttaaatc aacttcttta gctacttttt
   103801 ccatagcttc atcaaaatta ttatttacat attctaaagt ttccttttca accttcataa
   103861 atctttcaac tatttctgga tgtttctctg caaagtctgt gctaacagca gttactatta
   103921 taccatctac taaaccttca ccatttgcta caagtttact acctgacttc atagctttaa
   103981 gagctgctgg cccagcaatc aatgcagcat ctacgctgcc atcagaaaga gctgctgatg
   104041 cctctggaat acccatatta acaaattcca catcatccat acttaatcct tctttatcaa
   104101 gtgctgaaat caatacctga tgtaatatag tcccttttgg gcctgccacc ttcttaccta
   104161 ctaaatctgc tgctgatttt attgaattat tattagtcaa aatcataaat ccttttggtg
   104221 acctgctata agtgtttaat atctttaact ctactccatt agatgcagct attaaagctg
   104281 atgtaccacc tagtgcatgt aagaagtcta tttctccagc agctaaagct tgtgtttgct
   104341 ctggacctgt agtaatttcg tggaagttaa cttttatatt atccttttta aattcctttc
   104401 caaataaatc atcctgtttc tgaattatag aaggaacatt taatggtgat tttacataag
   104461 ttaaatttat ttctgaaagt ttttctccat tatttttttt agcacatcca gctaaagatg
   104521 ctgttgcaag tgttaatatc gttataccta tcaatagctt ttttaatttc atttacttta
   104581 ctccttaaaa tattattaat ttctttaaat gcctttattt gacttcattg tcattaaaat
   104641 atcttttttt aatttaatat agtaatctga agttaaatct ctattataac catcttctat
   104701 attaaattct tttacttttc tttcgtctgt gaaaacaact attttcttgc ctatctttaa
   104761 cgcttcatca atatcatgag ttacaaatat cacgccttta ttagttgact tatgtattct
   104821 tataacttca ttttgcatat caatccttgt aaaataatct aatgccgaaa aaggctcgtc
   104881 cataagcaac atatctggat tgaaagaaag agctctagct atgcttactc tctgcgccat
   104941 acctcctgac aattcatttg gataagagtt tttaaatttc tgcaagttca tcatcttaag
   105001 atatttttct acatcaatat tacttttcct attatattta tttgatttgt tcaaattatc
   105061 atttgtttct aagcttctaa aattatcatt tataatttta ctcctaattc ttttattgtg
   105121 tttaaatttt ctaagcacct tgtttaaaat agtatttttt ctttgattat gaaaagctat
   105181 attttcactt acgtttaacc aaggcattaa tctactctcc tgaaaaacaa aaccaacatt
   105241 aggtctatac tctttattat cattaataaa cctaatttca ccactattta taccttcaag
   105301 tgatgcaatt gctctaagca aggtagtctt tccacaacca ctttcaccta aaattactgt
   105361 tatatggttt ctatctatgt ttaaagagat atcactaaga actacatgtt ctttattgtc
   105421 aactttataa cttttatata aatttctaat tatatatcca gagtcacata ctaaattatt
   105481 catatgcttc caccatcttt cccttactta ccttcttcac aataatcgaa aatatgtaat
   105541 ctgtaattat tcctaaaagt ccaattacga ttatccctac aataacaaca tctgttctag
   105601 acatttcttt tccatcagat atcaagtatc caagaccaga tgaagctgct acaagttctg
   105661 ccccaataat tgctctaaag ctatatccaa gagctaactt taacccaaca gcaatatcaa
   105721 gaatggcatt tggtattatt attttaaata ttatctgaag ctttgaaaac tcaaatactc
   105781 tacccacttc aatcagtttt gagtcacaat ttttaatccc tttcaatgtg cttgtaaaga
   105841 ttgggaaaaa agatgctaaa actataatta taatttttga ttcctctcct ataccaaacc
   105901 ataatataag cattggtatt aaagcaaggg gaggtgtatt ccttaaaaaa tttattagag
   105961 atttaaagta ttcgtatact ccactataaa ttccaaagaa tatccctaaa ggcacaccta
   106021 tagcagtact tattgcaaaa cctatcaaaa ctcttttcat acttgcatat acattaataa
   106081 atattgaacc atcacttatc atatttaaaa atgtactata taccttttca ggtgatggta
   106141 atatataatc actccaaata ccaagataat ttgtaatttt ccataataaa agaattataa
   106201 aaaatatcag aacactcttt actagcctta aaaacttatt attaaattta ttgaccattt
   106261 acaaaccatc tccattatta caaccatctt tacaataaaa catttctact atgtcatact
   106321 tatcttcaaa accatttctt attttttgta tttcacttaa tatttcgtct tcacttgata
   106381 cttcaagaac tttttcaaaa gtatctttga aatatcctaa tggaattggt gattcatcta
   106441 tttttccaag tgattttaca ccttcttgtt cagcaaactc tttccatgta taaaacatag
   106501 cattaccctt atccttaaac ttttcacttg caaagtctct taattgtgta catggacagg
   106561 ttactaccaa catatcatct ttacttttta tatatttatc gtataaaacc ctacaagtcc
   106621 ttactaatat tggttctatc ataggtactt caaaattatt tatcaaatta tttcttttta
   106681 aaagacttat actttctgga catctacaat ccaacattgt attttcagtc ttttttgtat
   106741 actctttgta ctgctttttt acatattcta actgtggttc acattctgtt attatgtacc
   106801 ccttttttat caaatttgct ttaataaggt gaaacttttc tccatacatt ctttctgcca
   106861 ctggatttat tagaagatat ttattcataa cgcctcctat tatttaatat tgaatattat
   106921 tatcaattaa tagtttaaat gagcacttaa attttgtcaa tatattaatt ttttcttaat
   106981 aaaacaattt ttatctacat tttttaatat tttaaatgaa atattaaata gtatatgtaa
   107041 tttattttaa ttaataatgc atacatctta cta
//
LOCUS       DAMJVG010000003       105976 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.003, whole genome shotgun sequence.
ACCESSION   DAMJVG010000003 DAMJVG010000000
VERSION     DAMJVG010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 105976)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 105976)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..105976
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.003"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(265..1146)
                     /locus_tag="PC512_000229"
     CDS             complement(265..1146)
                     /locus_tag="PC512_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline iminopeptidase-family hydrolase"
                     /protein_id="HDF2440009.1"
                     /translation="MKITEGYMPFKGFKTYYRIVGENTEGKKPLVLLHGGPGSTHNYF
                     EVLDKIAESGRQVIMYDQIGCGNSFVEGHPELFNADTWIEELIELRKHLGLDEIHLLG
                     QSWGGMQAIWYAIEYKPKGIKSYILSSTLSSAKLWEKEQKRRISYMSEVDQKALLDAV
                     NTGDYSSKEYNDALERFMEMYCAGEVTEDSPECLRRPKKSGSEAYIVGWGQNEFSPTG
                     TLSGYEFTDRLHEIKEPCLVTSGAIDLCSPYIAKTMYDRIPNSKWELFEYSRHMPFVE
                     ENEKYIKVLTEWLNAND"
     gene            1602..2576
                     /locus_tag="PC512_000230"
     CDS             1602..2576
                     /locus_tag="PC512_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440010.1"
                     /translation="MNNINSLKVIKLSLGCSLAIFIAWLLKLEYSMVAGVIVLLTVKD
                     TKRETLKGSIGKIYGFLLCTIFSYLCFNILGYNLTSFSIFIFIIIPLCFLLNIQDVIA
                     MCVVIASHYYLQGETSIKWILNEAGIFAVGTGIGVLINMYIPTNIHKIHEVQKKLQEE
                     VSIVLIDIADIIVNPKKENGYSRDLYTLNSLIDSSISETYDNINNTLLSDTRFFLEHM
                     DIIKSQRDILENLYSYVSQLNSTPPQAHILSAFIHKIGYTEFEAETGNLLLEELKRLM
                     LSMKNQPLPVDRTEFENRAILFLCLTELKQFLVNRKHAQILRDNNFYK"
     gene            complement(2692..3753)
                     /locus_tag="PC512_000231"
     CDS             complement(2692..3753)
                     /locus_tag="PC512_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HDF2440011.1"
                     /translation="MKKIRKLTTKLLITTIVLISGMSMTVYGMTAKEVTAKTPKSYVT
                     GTNSVYGPKLSQAQLNSVAQATADFMNKKITKNMTTDAKILVAYNHIKNNTTYVDWNA
                     VEGANTAYTLVTKKGACSGMARSMKALCDAMGIESYYVHSTSNDHQWNLIRFGDGRLY
                     HVDIDANKSAGKDIIYKSLSHPLPFDKTAYPKVGAIVQTVKPEQTQKPAPPGKHTMLP
                     HQEGAKAVGNFGKKGEDINEKHVMYEGVRCSVVNSSVNTITFTGSESNLDPSNLTIAV
                     IGFMNTPYGMFALAPEGKPVEYPFKYDKPFSLDFSGKNRSGAELAKYCKKNDVTIKIE
                     ITDEKANIGLGQIMYVRYE"
     gene            complement(4365..5216)
                     /locus_tag="PC512_000232"
     CDS             complement(4365..5216)
                     /locus_tag="PC512_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF2440012.1"
                     /translation="MSCILKLKQIYEDLTEVDKKIADYILNNTEAISKLSVSELASNS
                     KTSTASIVRFSRKMGYSGFGDLKIEIAKDLMGKENEYTYVDENYDCNIDSVINKITNK
                     NIETINQTRLLNEKDIIKEAVEQIIKAKNVYIFGVGGSALVALDLQMKLLRINKQAFT
                     SLDSHTQLMVSSNVDKEDIAIAISYSGESKEVIKSIENAKLKGCKVICITKYSDNHLS
                     KISDLKLVVPNIEKRLREGAISSRIAMLTLIDIIYISIIQENLNEAEQKLQETKRILD
                     YLNINNA"
     gene            complement(5233..6153)
                     /locus_tag="PC512_000233"
     CDS             complement(5233..6153)
                     /locus_tag="PC512_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA reductase"
                     /protein_id="HDF2440013.1"
                     /translation="MYFLGVDGGGTKTTFTLVDEELNIVGTITKGTCHYNQIGFDNLT
                     KLLITGLEEVCKDAKINVEEITYAFVGLAGYGKIKEVLYALEVATKNAYSHINYTLGN
                     DVEIALAGSLNGEKGINIIAGTGSIAQALDKDGNLHRCGGWGYVLGDEGSAYYIGMAT
                     LKMFTMQSDGRCSKTKLYDLIKRHLNIENDYDIIKYVNDEIQGDRIEIAKFATICLKA
                     VIEGDNTASKIFDDAAYELSRLIIGLEHHFEQGTKIKVSYSGGVFKSGDLILEPLKKY
                     LNKTRFGIVRPVLTPDLGACLLAKKKYYSK"
     gene            complement(6263..7177)
                     /gene="murQ"
                     /locus_tag="PC512_000234"
     CDS             complement(6263..7177)
                     /gene="murQ"
                     /locus_tag="PC512_000234"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HDF2440014.1"
                     /translation="MLIKTLENLVTEGRNKNTLQIDKEDTLGIIELINNEDKTVAYAV
                     EEQKESIAKAVNIIVDRMKQGGRLFYIGAGTSGRIGILDATECPPTYGVDFELVQAII
                     AGGNQAIFKAIEGAEDDKELGKQDIIDRGVTSKDVICGIAASGRTPYVIGAMEYAKEL
                     GCAVLSITMNPNSEMSKKADLPINIIVGAEVIMGSTRMKSGTAQKMVCNMLTTASMVK
                     MGKVYSNLMVDVKTSNEKLVERAKRIIMIATNVKYDVAEKFLEEADNSVKLAIFMIKS
                     GLDKDSAKSILDRQEGYISEALKSIEKL"
     gene            complement(7276..8373)
                     /locus_tag="PC512_000235"
     CDS             complement(7276..8373)
                     /locus_tag="PC512_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HDF2440015.1"
                     /translation="MGRLGISIYPEKTTSKEIYDYIDKAAENGFTRIFSCLLSVKDTK
                     ENIIKKFKRINEYAKFKGFEVILDVNPRVFGELEISYKDLTFFKKTKADGIRLDIGFT
                     GSEEALMTFNPQNLKIEINMSNNTNYIDTIMDYQPNKENLTGCHNFYPHRYSGLNLEH
                     FIKCTERFNKYGLRTAVFVTSQNETTFGPWPVTDGLPTIEMHRNLPIDIQVKHIIAMN
                     NINDIIISNCYPTYEELKVLGSMRKDMVTFDVAIEENIREVEKKILFEEIHFNRGDIS
                     DSLIRSTQSRVKYKGYKFELFNTPKIIKRGDIVIESSEYGHYAGELQIALTDMKNSGK
                     SNVVGYIRKEELFILDYIKPWQKFNFKPSTK"
     gene            complement(8606..9952)
                     /locus_tag="PC512_000236"
     CDS             complement(8606..9952)
                     /locus_tag="PC512_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2440016.1"
                     /translation="MLDKFTEFLDTKLSTSMARLAEQRHLRAVRDGIVASLPLIIVGS
                     FFLILAFPPLPDSWGVTQYLKENAVTILLPYRMTFFIISVYSTFGIGYSLAKSYKLDG
                     LTGGLLATATFLLTIVPTAIEGLTPELLKIVEKSPELLAWYNSIPQGWQMPMANLGGG
                     SMFVAIVTSIIGVEIYRFTDKSKFKITMPEAVPASVTRSFEALTPAALIIILMAIVTY
                     FLGFDWHGFIAKLVTPLVSATDTLPSVIILIFLITFFWSFGIHGVSIIGSLARPLWIQ
                     LLDANTASYAAGQAVPGIAAEPFFQWFIWIGGSGATIGLALLLAFRAKSAYGKSLGKA
                     TVIPAIFNINEPIIFGAPIVLNPILIIPFVVAPIVMATVSWFAMSANLVSRVVVTAPW
                     TLPGPVGAYLATGGDWRASVLNLLCIAISIIIYYPFVKMYDKRLLHEEKVEEQEAY"
     gene            complement(10041..10349)
                     /locus_tag="PC512_000237"
     CDS             complement(10041..10349)
                     /locus_tag="PC512_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2440017.1"
                     /translation="MRVLFVCSSGMSSAIAVNALQKEGAKNGIDIDVLAVGTQEFENE
                     VKNGWDIAMVAPQVRHRFDYLKAFADEVSVPCALIQAQAYSPLGGPKLLKQVQELLSK
                     "
     gene            complement(10611..11009)
                     /locus_tag="PC512_000238"
     CDS             complement(10611..11009)
                     /locus_tag="PC512_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440018.1"
                     /translation="MSNNKKKKRKKNNNYKNAKSTKSNKNTKKQMEKNQRTDYNIPTI
                     SFKSGLILIVSSLVSTVVFPLLLSIFGIDNRFGVVIGNSLITSFAVAYTRYFVETKRG
                     FSLGFFRLYILFALSFAIIGYFWIYKGIHI"
     gene            complement(11011..12171)
                     /locus_tag="PC512_000239"
     CDS             complement(11011..12171)
                     /locus_tag="PC512_000239"
                     /EC_number="2.7.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anhydro-N-acetylmuramic acid kinase"
                     /protein_id="HDF2440019.1"
                     /translation="MITMYSVGLMSGTSLDGVDAVLAEISGNGRNTKVKQIEFITLEI
                     PKDIKDEIRKCCIEEESSVDLICSLNFKLGYLFSKAVKSVCHKANFHIANLDFIASHG
                     QTIFHIPRSYNNFVSSTLQIGEPAVIAYETNTKVISNFRVMDIAAGGEGAPLVPYSEF
                     LLYSDNNKNLALQNIGGIGNITIIPKSCNIDDVFAFDTGPGNMIIDGVCQRLFNRKYD
                     KNGYFASKGKINEEMLKDLMSHKYLSQAPPKSTGREVFGQVYLDNMLNKYKHVDKYDL
                     IATVTMFTAKAIYYNYKNFILPKVNVDTLLIGGGGAHNLTLIGYIKELLLEVEVLTQD
                     EYGYSSDAKEALAFVILGNETLNNSFSNVISATGAKNKVILGNITPKPFGGK"
     gene            complement(12602..13621)
                     /locus_tag="PC512_000240"
     CDS             complement(12602..13621)
                     /locus_tag="PC512_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2440020.1"
                     /translation="MLVKYLKGRSKYIALPLVVVSIINIYLFAIDIFKNKYSELIYLD
                     FLVLFIIMVFFVIDYINFRNSYTNLYNCIENSGEIDSYLVDGQSFEENLIKDIIENLK
                     IKNNSDIETYKQSLKELDEYIAKWVHEIKIPISSLSIITDRLSSIEDSLDIKNQVAKI
                     NFLVNSILYSSRSNTMFEDVFINKFNLEKLVKMSIKNNSFLLIKNNVEVSLNELENDV
                     YTDSKCMSYVLDQIINNAIKYSKEVGKIEFNSKKLENGVVLSIKDFGIGINEEDISRV
                     FDKGFTGKNGRNQLYKSTGMGMYFVKKMIDSLGHEIEVCSKIGSYTIFNIYFYDISDY
                     LSIDS"
     gene            complement(13615..14295)
                     /locus_tag="PC512_000241"
     CDS             complement(13615..14295)
                     /locus_tag="PC512_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2440021.1"
                     /translation="MYRILLVEDDIDLSKEIALALEKWGFKVELIDDFEVVLDEFIDK
                     KPDVVLLDVNLPLYNGFYWCEKIRAISNVPLIFLSSRDSDMDLIMGINNGADDYITKP
                     FSIEILVTKINGIIRRVYNYSDSNSILYCEDLMFDVGKGIIKHKYKDKSIELTKNEIK
                     ILTLLLKNKNRVVSRESLMMTLWDNDEFVTDNALTVNMNRLRSKVKELGFDDFIKTKK
                     GIGYIIQC"
     gene            complement(14447..16354)
                     /locus_tag="PC512_000242"
     CDS             complement(14447..16354)
                     /locus_tag="PC512_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDF2440022.1"
                     /translation="MSILGIAYNNFKSNIRTYLAFFISMVFSVVVLTNFELLRYGDAI
                     NVLQEENKKFTLSVLVAVIMILSVFLFFFIWYATNIFFKNRSKEIGILSFMGLDLYTI
                     GKIYFVENMLIGISSCITGIIIGIITSRFFQVVIIKLSGFNIKVSNGLSIEAILYATL
                     IFISIFIIMAVKGFITICRSSVINLINISKKQEKIPKVGIGIYILAIVSIIVIGYGYY
                     LSTNIRTGDITSVLPVIGIIIVGTYGLFKSVMPVIFDIIIKNKKILFNGNNIIAINNI
                     NYRLNKNYKTYAIIAIIITTTISTLGASVAMKHIHKNAQEQRNVYTISIVSMDKDEVN
                     KKQIENIIKDTNKIKYSVNPELTILKKTDIKEAYDTTDTIMKYSDFCNTLKVNGNDKE
                     LKEYGERLVSGNNVIELKSPQTIASIATKEAKIKLDGQLYNISRGEVKVPVLGTGLNQ
                     SIIVVNDDTYFKLRDKGQQVYFYGAKVFQEENSQVMFNNIEKNLSLKNGYIQNGYKAQ
                     GESQWMKFAYVVLVFLFLVFAIVAGSIIYMKIYSDAYEDKEKYKILLKIGTTEKDINR
                     AILKEVAIFYTLPMLSATISSYFALRLAGDLLMTDLFGIYILSLVICLIIFIIYGAVS
                     VNKFKSVVYKN"
     gene            complement(16355..17107)
                     /locus_tag="PC512_000243"
     CDS             complement(16355..17107)
                     /locus_tag="PC512_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2440023.1"
                     /translation="MKEILKIKNISKDYGIKGFKTNVLKNISLTVNEGDFISIMGPSG
                     AGKTTLLNLMSTLDKQTSGEIILDGINISKVKNNELSKLRREKIGFIFQDYNLLDNMK
                     LMDNIALPLALGKKKSKEIEAKVFSIAKKFGLENHLDKYPYQLSGGQKQRGAAARSLI
                     TNPTVIFADEPTGALDSKSAYELLESLEKINRENNATIIMITHDPLTASYSNEVYMIN
                     DGNIKCKLNKGNSRKEFYGKIMDMLASMGGEM"
     gene            complement(17423..18577)
                     /locus_tag="PC512_000244"
     CDS             complement(17423..18577)
                     /locus_tag="PC512_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2440024.1"
                     /translation="MINKAIKFKFIIFYFFSYIIFAFASTKFTPFLSKLGYSAFERGI
                     ILSSYAITNILFQLLFGVLADKYQTMKKIVLISLSVYGIASVIMFSTESATFIIYLLL
                     VALSGGLLNTCCSLYDTWIIGCGDNINNYLSFIKTFGSIGWAIGSMVASYLILRFSYF
                     GLSVAIGLIVVLLIINILLLPDIEKINKKINVTNKDIIELLKDKKYILLVCILFLLYS
                     MVVANNCTVIDKMIALNATNSQISLKWSLQSLLEIPTYLAGSYLLKKYSSLNLLKLSA
                     IMITVQFLLFALTNDSNIIIILCVFQVFSTPLILITSKRLIFEVSPKKLRSSSQLIAL
                     SIFMGGSSLIIPTVAGFLSINIGYNYTLMVLSLFGCLAYCLIVLLNYLQE"
     gene            complement(18580..19047)
                     /locus_tag="PC512_000245"
     CDS             complement(18580..19047)
                     /locus_tag="PC512_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2440025.1"
                     /translation="MFFKRKKEAITINSYIDGKIINLGEIPDKVFSTKVMGDGFAMIA
                     KDNILKSPTKGVISFIAQTNHAIGIKLQNDVQILIHIGLDSATTKKENFKLEVKQGQE
                     VNMGEKLVEIDNKLLENTLYIPLVIVENPNTVKYHLSNLNQEGNSGIKVINFD"
     gene            complement(19061..19549)
                     /locus_tag="PC512_000246"
     CDS             complement(19061..19549)
                     /locus_tag="PC512_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440026.1"
                     /translation="MITNKIKNITAVLKDENIFLSVVMVCFLILPVLYIVYLELTSLF
                     TNISFSQLLNNDVNASLNLISNFSAVYSAYVIYNIKKNKEIKENMIAFYLVLLGQIFQ
                     IYTITIVIMFTYIYKFVGIKQIISSIKELQWGKSYKALFSSIAVCLISLFVMIIRIKL
                     IM"
     gene            complement(19563..20894)
                     /locus_tag="PC512_000247"
     CDS             complement(19563..20894)
                     /locus_tag="PC512_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HDF2440027.1"
                     /translation="MERKRQRILIAGGGSTYTAGIVTMLIESVAKFPIESIKLYDNND
                     ERQRKVAEACAIIVREKNPEIKFSYTTNPEEAFTDIDFVMAQIRVGLYALREQDEKIP
                     LKYGVVGQETCGAGGIAYGLRTIGPIIEMIDYMEKYSPNAWMLNYSNPAAIVAEACRV
                     LRPNSRIINICDMPVCLEEIFARVLGLNSRKDFDVRYYGLNHFGWWTSIKDKEGNDLM
                     PKLQEYCAKKGYEEFTPQGQHKESSWLETMRAAKDLLEIEPTTLPNTYLKYYLMADET
                     VEHANPNYTRANEIMDRREKDTFEECERIIKNGTARDTWFDASEHSQFIVELACALAF
                     NTQERFLLIVPNNGAIENFADDAMVEIPCLVGKDMVEPMSIGKIPTFQKGLMEQQVAS
                     EKLAVEAWIEKSYQKLWQSFTMSKTVPSAKVAKEILDEMIVANKDFWPTFK"
     gene            complement(20908..22473)
                     /locus_tag="PC512_000248"
     CDS             complement(20908..22473)
                     /locus_tag="PC512_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003233606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDF2440028.1"
                     /translation="MMKKIQRFGGAMFTPTLLFAFAGIMVGFSIVFQNQSIMGSLATP
                     ENIWYQFWGVISSGAWMVFNQLPLLFAISLPIALAKKQQARACMEALATYLTFNYFVG
                     SMLSFWGKSFGVDFAAEISAGSGLVSIAGIKTLDTGMVGALLISGIVIYIHNRFYDKE
                     LPDFIGLFRGSSLVVAICFFVMIPVALLTCFIWPHIQNVIRHLQTFFINSGNIGVWCY
                     AFLQKILIPTGLHHFVYAPICYDSVVVPGGTSVYWATHIQDFQTSAKTLKEMYPIGFS
                     LSGLSKVFGSLGVFGAFYVTAKPEKKKKVLGLMIPATLTAVLTGITEPLEFTFLFVAP
                     LLFLVHAFLDACLQTISFALGVVGDFGGGIINWVVLNWLPLGMYHWKVYVVQVVVGII
                     FSFIWFFVFTFLIKKFDMKTPGREEDSEETKLYTKNEYLETKDEKGNKLSKASQQASE
                     YIKLVGGAENVVDVTNCATRLRLTLKDDSIISKEEDFKAVGAHGLVHNGKAIQIIIGL
                     SVPSVREEFENLL"
     gene            complement(22643..23428)
                     /locus_tag="PC512_000249"
     CDS             complement(22643..23428)
                     /locus_tag="PC512_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF2440029.1"
                     /translation="MRLEEMIFLNYNKLNDTDLLIWKYITANKKHCSKMSINELAMKC
                     NVSRATITRFVKKLDLKGFSEFKVLLSWESEKVHVIENQSFDIACNSIIKYVEDQKNK
                     DYDALCKLLYESRTIYAYGSGDIQNVVAKQIKRMFLSCQEIIYDFEGRTFDDSFYNIV
                     SKNDVMIIISLSGENENTLNIARRLKLIGTKIISITEFKNNTLTDLSDESIYISATNI
                     SFLQMHPSYKLTMLYFILIELLFIKYSIYKRHRMITEGIDCKL"
     gene            complement(23595..24794)
                     /locus_tag="PC512_000250"
     CDS             complement(23595..24794)
                     /locus_tag="PC512_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S41"
                     /protein_id="HDF2440030.1"
                     /translation="MKKKVLFLVIILAFIILLGNSTYSQKNQLSEEEKVDDFNYVYNV
                     VKTGYPYLGVNKRLNNIDWLANKDEYTKRIKNTENDEEFIEEMSSILSDLNNKHTEVI
                     DNKKRYELFKKSYSNNDWYDFLNDKKVVDRYDSMNLKIKMPDDIFVKKELILKDVIKG
                     QIGYMYLPSMSSKNGSINNDLKIIGDYIDTLEKHKALIIDIRGNLGGSDSYWQGIVSK
                     LIKNDVKINGYRIYRNNNEIVKQYTNARNIKLNPVENLPTSVKENAPKEIIKDFNDFE
                     DTSYTIKSTDDSKFKGNIYLLVDRKIYSSSESFAMFCKETKFATLVGETTGGDGGCID
                     PVLFNLKNSGLIVRMASCMYLNKNGICDEEFKTIPEFKVKDCKRTADFKDDNCIRKAL
                     ELENINY"
     gene            complement(25316..26653)
                     /gene="xylA"
                     /locus_tag="PC512_000251"
     CDS             complement(25316..26653)
                     /gene="xylA"
                     /locus_tag="PC512_000251"
                     /EC_number="5.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylose isomerase"
                     /protein_id="HDF2440031.1"
                     /translation="MSEIFKGIGQIKFEGVKSDNELAFRYYNPEQVVGNKTMKEHLRF
                     AMSYWHTLCGEGNDPFGVGTVERPWNNITDPIEIAKIKVDAGFEFMSKMGIEYFCFHD
                     RDIAPEGRDLEETNKILDEIVEYIKVNMEKTGIKLLWGTANMFGNPRFVHGASTTCNA
                     DVYAYAAAQVKKAMEITKYLGGENFVFWGGREGYETLLNTNTELEMDNFARFLQMAVD
                     YAKEIGFTGQFLIEPKPKEPTKHQYDFDTATVLGFLRKYNLDKYFKMNIEANHATLAG
                     HTFQHELNIARINNVLGSIDANQGDLLLGWDTDQFPTNIYDATLAMYEVLKQGGIAPG
                     GFNFDSKVRRASFEVEDLFLAYIAGMDTFAKGLLIAHKLLEDEVFENFTKERYASFSE
                     GIGKDIVEGKVGFKELESYALQMPVIKNKSGRQEMLEAILNRYIYEVDTISNK"
     gene            complement(26749..28299)
                     /gene="xylB"
                     /locus_tag="PC512_000252"
     CDS             complement(26749..28299)
                     /gene="xylB"
                     /locus_tag="PC512_000252"
                     /EC_number="2.7.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulokinase"
                     /protein_id="HDF2440032.1"
                     /translation="MKLEYVLGVDIGTSGTKTVLFDKLGNTIKSCTYEYPLIQEKSGW
                     AEQDANDWWKAVVESIREVVQSSNISSECIKGIGLSGQMHGLVMLDNEGKTLRNSIIW
                     CDQRTVKECEEITDLVGEERLIEITANPALTGFTASKILWVRNNEPDIYKNTNKILLP
                     KDYIRYKLTGEYATEVSDASGMQLLDIRKRDWSDEVLEKLNIDKNLLGKVYESQEITG
                     YVTRDVASLTGLKEGTIVVGGAGDQAAGAIGNGIVKDGVVSSTIGTSGVVFAYTKEPK
                     IDKEGRVHTFCHAIPNTWHVMGVTQGAGLSLKWFKDNFCQSEVEVSNSLGEDVYEIIN
                     NQVSQVPTGCNGLLYLPYMMGERTPHLDPYARGVFFGLSPIHSKKEIARSIMEGVSYS
                     LKDCMDIIENLNIDVNEVRASGGGGKSKVWRQMQADMFNQDVYTINSSEGPALGVAIL
                     ALVGAGIYENIQKACDAIIKTSTKLEPISENVDTYNIYHRLYKRIYKSLKDDFKLLDE
                     VVNAKINN"
     gene            28507..29667
                     /locus_tag="PC512_000253"
     CDS             28507..29667
                     /locus_tag="PC512_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HDF2440033.1"
                     /translation="MVTDKYTIREMNERLVLEQIIKNGPISRASIASTIGLNKATISA
                     ITKKLIDESLVHEIGIGNSTHSGGRKPILLVFNKCAGISLSMDIGYDYIFSSLSYLDG
                     TIINSKKLTDIQVSKDNVIQLIDEIINSYNISKIDTPYKVIGLTLAIHGITCENKVLF
                     TPYYNLNEIDLYSILSKKYDFPIHIENEANLTALAENTFSTVHNSLLSLSIHSGFGSG
                     IIINNKLYSGRNGMSGEIGHTIIMPNGKLCPCGNRGCLEQYCSEKKVFEQLSSLENIP
                     KIDSDIVKQLYYEDNHNAKKVIHEFCSYLTIAINNAITTYAPEIIYLNSQIISDIPEI
                     LQITKDMLVSSFNKGINIEISSLGSEASLYGGSAVNIKSFLNIQNLTLINEI"
     gene            complement(29823..30227)
                     /locus_tag="PC512_000254"
     CDS             complement(29823..30227)
                     /locus_tag="PC512_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2440034.1"
                     /translation="MNSIILMSHGNMAEEVLNSAKMIIGDSIDYPTVNMKQDDGIEGT
                     IEKLKKALEVYKESSEIIIMADLLGGTPCNAALLVANNDSRIKIISGLNLGMVIESAF
                     LDTKELAAKLEKIGKDNISMVEQNASLLSDDE"
     gene            complement(30248..30730)
                     /locus_tag="PC512_000255"
     CDS             complement(30248..30730)
                     /locus_tag="PC512_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2440035.1"
                     /translation="MEMKGIKNIRIDDRLIHGQVATMWSNKLGVTRLMVVNDAVANNS
                     VQKQVLRMATPAGIASSIITEETAIKNITAGKYEGQNVLLIVKSPVDLIPFVEAGFKI
                     HNINVGNMSSRKDTTVLRPNISVTEEEKEAFKRLLDEGIEITTIMTPDDKKTYLVDIL
                     "
     gene            complement(30750..31559)
                     /locus_tag="PC512_000256"
     CDS             complement(30750..31559)
                     /locus_tag="PC512_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDF2440036.1"
                     /translation="MSDKVSLNKSNEKVKKSVLWRWFFTSSVSSNYEKMQALAYCYAV
                     LPFLKVVYKDNPEKLQSAVLNHLQFFNTNPWVAPYILGINVAMEELSSEETEEAVASI
                     KTGLMGPVAGLGDSLFVVIPWTIFGAIAANMAIDGSPFGILLWIVVSVALKLLSIPLF
                     NAGYTSGTKLISSIEKSLKILTESTSILGLMVVGALIPSVVKANVALNFQQGDFTMKG
                     QEILDQIMPGLVPAILVVIVYWALKKNIKPIYLILGVMVVSIILYALGILK"
     gene            complement(31552..32331)
                     /locus_tag="PC512_000257"
     CDS             complement(31552..32331)
                     /locus_tag="PC512_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2440037.1"
                     /translation="MEPQLWQLLLIVLYGFFINYEKNSTMFGTYQPVTAGFITGLILG
                     DINTGLYIGGTLQLLSLGISNFGGASIPDYQTASIVATFITITTKQEASVGISIGIPV
                     ALLMVQLDVLRNTIGIWLVHKAEDGAKKGNYKNITYMQMLGVLLTAATTGIPVALSVI
                     FGPSLINTILKYTPEWLTGGLTVAGGLLPAVGIGLLLRYLPAKEYFSYLVIGFVLAVY
                     MKVPLLGVALIGGAIALIIYKKNLENQEQQYTVVGGMDEDE"
     gene            complement(32331..34409)
                     /locus_tag="PC512_000258"
     CDS             complement(32331..34409)
                     /locus_tag="PC512_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HDF2440038.1"
                     /translation="MIKISEDYIEKRFDNELLRIEAWGKNSLRIRSFVDQNFVDENYA
                     LNEKPKLNKDDITINKNEDGSAIIKNGKIKAVLDHRDRITFYNDKNEILLKEYIRLRA
                     VKHDDGGEDVGTIEITKDFNSTLKLKSREYRPSYSGEFEVTTRFESEPSEKIFGMGQY
                     QHKFLDLKNTVLELAQRNSQISVPFYISSLGYGLLWNNPGIGKVSFAKNMTEWKMFST
                     NFIDYWITCGESPKELNKNYSQVTGTVPMMPENLLGLWQSKLRYRTSEEVLDVVKEYS
                     KRGIKLSSIAIDYFHWPKQGEYKFDLDYWKNPKELVKKLKEEYSVEPIVSVWPTVQSD
                     AENYNDYLENGYLVNVNRGVRMTMQIQGNTVFVDMTNENAREYVWDRIDKNYKQLGID
                     YYWLDVAEPGYSVYDFDNYRYKKGNVLSCGNIYPIDYLKMIYDGLHNDIESVVTLVRG
                     AWAGAQKYGALVWSGDIDSSFEAFNNQVNTGLNMGLAGIPWWTTDIGGFHGGNPKDPE
                     FRELMVRWFQYATFSPILRMHGDRLPHSKPLSNKGGGSMVTGAPNEIWSYGEEVEVIL
                     TKFIKIRESLKTYLKKLMKEAHEDGTPVMRTLFYEFPEDDKTWEVDNTYMLGDEILVA
                     PIMNYKDRSRKVYLPKGHTWENIFSGVSYEGGKTYEVECPLEEIPIFLKQDSSYNFKE
                     LKNILGEVKS"
     gene            complement(35208..35729)
                     /locus_tag="PC512_000259"
     CDS             complement(35208..35729)
                     /locus_tag="PC512_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HDF2440039.1"
                     /translation="MKRNREIVVVCHCILNCNSKVEGLSEFKGAQNIAIDLINKGYGI
                     IQLPCPEMIMYGINRWGHVKEQFDNLFFREQCRQMLIPHVRQFDEYLKNDYDIKSIIA
                     IDGSPSCGYNKTCSSKRWFGELSGCNELMDKINDIQMVDGKGIFIEELEKLLKEYNLN
                     IPIVGFDELREDK"
     gene            35895..36461
                     /locus_tag="PC512_000260"
     CDS             35895..36461
                     /locus_tag="PC512_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDF2440040.1"
                     /translation="MDTKKVTFSSMCIVINIVLGMVISMINIPLLFLDTIGTVLGAVV
                     LGPFWSALIGGCTNLVLGVISGPTNIPFALVNIVLGLIVGYISKKKGFGYKEAIITGV
                     ILSIVCPLIGTPISVLLFGGLSGSGADLLVGFLVQSGQKIFTAAFFPRILSNIVDKPL
                     SCIMVVYFISKMPKGFIKQYSKNTSSSY"
     gene            complement(36678..38741)
                     /locus_tag="PC512_000261"
     CDS             complement(36678..38741)
                     /locus_tag="PC512_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF262 domain-containing protein"
                     /protein_id="HDF2440041.1"
                     /translation="MKAGEIEFLSYLEGSNKSFVVPVYQRNYNWKKEQCKRLFDDLED
                     IIDSGFRTHFLGSVVSIYSMGKEYLIIDGQQRVTTVSILLIAMCQIIKEFGESKGIIT
                     TEEQIKECYLINKHSRDKDGKIKLKPIAEDRKAYYELFEEEMNTDRNSNIVSNYLYFY
                     NRIKEDNISIDDLFDAIQKLTIVEIELKNGEDDPQLIFESLNSTGLDLSEADRVRNFV
                     LMGRSSKLQEEFYNNYWYKIEKNTSSNVSSFIRDYLTIKERSIPNKNKVYFSFKRYVS
                     DNGIDIEILLKDLLKFSNYYREISYSCTDDNDVNKVLKRINKLEIFVSYPFILELFDD
                     YNEGIINKKVLVESLNLVECFILRRIVCDVPPNALNKVFMNLGREIKKFSDYKENYSN
                     ILRYIFINKKSSQRFPTDSEFSNAFETKDIYNTKSKNKLYILERLENYNNKEIVDLEN
                     LINNNMLNIEHIMPQTLTNKWKESLGDNYKEIHDKYLHTIGNLTLTGYNSKLSNKTFE
                     EKKEMEDGFKDSRLYLNKYISSIDKWNEEEIKNRTKILLDRAVEIWKYPSVTYEPPSN
                     SENIFTLEDDDVNFTNESIVSFSILGESYKAKNWTEFYEQVALTLYDLDSVRFNSIVD
                     KTYKRDFIDNIKSRDAYKLRKGIKISENIYLETNLNTEAKLNIIRFLLNEFDIELNEV
                     IFSIK"
     gene            complement(39122..42457)
                     /locus_tag="PC512_000262"
     CDS             complement(39122..42457)
                     /locus_tag="PC512_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HDF2440042.1"
                     /translation="MGNFDFLQKKKNFNSFNTACLEAEKSILVSPSTCATITRRALEL
                     AVKWLYANDSDLVLPYQDNLSTLIHNNSFIELIDYDMLPLLKYIVKLGNLSVHTSANI
                     ERGEAILSLNNLHQFVSWIDYCYSDEYTAEDFNEDLLLHGEEKRTRPDELKNLYERLS
                     SKDKKLEEVIKENEELRKSLTEKRKVNTVNYDFKIDEVSEFETRKRYINIELKLAGWE
                     FGKDIWEEIEVQGMPNESGVGYVDYVLYGENGKPLAVVEAKRTSKDPKIGQQQAKLYA
                     DCLEKRYSQRPVIFLTNGFDMYIWDDYSDRKVYGFYKKSELQLMIDRRKSKKSLSSVT
                     INDEISNRYYQKEAIRAVCEALENKQRKTLLVCATGTGKTRIAISIVDVLSRHNWIKN
                     ILFLADRKALVKQAKKSFTKLLPNLALCNLLDSKDSPEDARMIFSTYPTMMNAIDDTK
                     SKDGKRLFTPGHFDLIIIDESHRSIYKKYKSIFDYFDSYLMGLTATPKDEIDKNTYSV
                     FDMENGVPTYAYEYNKAVEDGYLVDYTSIEFKTKIMEDGIKYDELSDEEKEEYENTFN
                     DDESIGDEIGNNAVNEWLFNSDTIDLVLNKLMTEGLKIEGEEKIGKTIIFAKNTKHAR
                     AIVERFNKLYPKYGGNFVKAVDYSINYVDSIIDDFSDKNKLPQIAVSVDMLDTGIDIP
                     EILNLVFFKKVRSKTKFWQMIGRGTRLCPDLLGVDMDKERFLIFDFCNNFEFFKFNPK
                     GFEGNKTETLTEKLFNIKVSMVKELQDIKYIEGEYAELRKELLEELITSVKALNEDSY
                     IVRMNLSYVHKYKNENVWSNIGAVAQNEIREYISPLITSYSDDELAKRFDVVMYNIQL
                     AYLQNNNASKGIRHVMATAEKLSKLGTIPQIQQQKYTIEKAMTEDFWEDSDIFEVEEV
                     RISLRELIKYLEKSSQKIYYTSFEDMIVAEDRNDSVYNANNLKNYKKKVEYYLNSHKD
                     ELAIFKLRNNKKITKQDVETLEEILLKQLGNCDDYKKEFGDTPVSQLVRRLVGLDREA
                     ANEAFSEFLNNKSFNTKQIHFVKLIVDYVVKNGFIEDNKVLMEDPFRTVGSIIDLFEN
                     HIEERNKLIKTINKIKENASEIG"
     gene            complement(42507..42935)
                     /locus_tag="PC512_000263"
     CDS             complement(42507..42935)
                     /locus_tag="PC512_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440043.1"
                     /translation="MVIRNKLSWNSIEEVNRDFGSCLYDLQNFKILYDKEEMPELWAR
                     YIKEGFKSYMVSFLELTKAMLYYKSIDLNIKSKNFYDYLLACEYHNLLPKNSSIVIET
                     LRKLRNDDSHGYDIPQFEDMYELFTENEEVFVSIRNSCKK"
     gene            complement(42925..43305)
                     /locus_tag="PC512_000264"
     CDS             complement(42925..43305)
                     /locus_tag="PC512_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HDF2440044.1"
                     /translation="MRNIPNEIKNSIINVFPKENTLAIIIFGSYGTDKHTSESDIDIA
                     WIPIKKVPITELATKTEALRNILDIDVDLKIVTDNYTIALKKAILEGEVIYKSKDFKD
                     YINKFYFENSDVIDILDWRDMYGN"
     gene            complement(43338..43646)
                     /locus_tag="PC512_000265"
     CDS             complement(43338..43646)
                     /locus_tag="PC512_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440045.1"
                     /translation="MNQIELDLYHNMVNIYKEADLQCNYKPTRFLQLINNKGALLAAK
                     ELINKEGATEGFTRLWECKRLDLSLEVLVLKEKYKELFTDEEREICINRLKDYGYKFN
                     "
     gene            complement(43691..44851)
                     /locus_tag="PC512_000266"
     CDS             complement(43691..44851)
                     /locus_tag="PC512_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HDF2440046.1"
                     /translation="MEYRLNEVFEFIRNGASIKQFDTKFGYPITRIETIANSYIDTNK
                     MGYADIKELGKLEDYLLKNGDILMSHINSEKHLGKSAIYEDINKKIIHGMNLLCLRPD
                     KEVCYPKYLNYFFNSNEFRRQLPRIIKKSVNQASFSVNDLKNLKVDLPEMEAQKDISK
                     VLDKAQELIDKRKEQIEALDELVKSRFIEMFGNFKEQKFVLLKDCTNFIDYRGKTPIL
                     SENGIRIINAKSVGNGVFKYINEYISENTYNSWMKRGFPVAGDVLFVTEGHTFGNVCR
                     IPKDLKKFAMGQRIITIQGDKKILNNAFLAQYMQTKAFRVEIDKYKTGSSAQGIRSKE
                     LQKILIPVPSIELQNKFEEFVNQVDKLKVGIKTSLKELEDNFNSLMQKAFKG"
     gene            complement(44855..46318)
                     /locus_tag="PC512_000267"
     CDS             complement(44855..46318)
                     /locus_tag="PC512_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HDF2440047.1"
                     /translation="MITGELRSKVDKIWETFWTGGLTNPLEVIEQFTYLLFIKGLDEV
                     ETKNEAEATLLGVSFEKIFDDEHQHLRWSKFSNEGNSEKMYEIVQNEVFPFIKKLHGN
                     KESAYAKYMGDAIFKIPTPLMLSKIVDGISNLELSKDRDTKGDLYEYLLSKVATAGTN
                     GQFRTPRHIIDMIVRLIKPTPEDIIVDPAAGSAGFLVSSQQYLRDNHSSLFLVQGLKE
                     HFNNGMFYGFDMDRTMLRIGAMNMMLHGVDNPNIEYKDSLSEVNTDKDKFTLVLANPP
                     FKGSLDYEAVSADLLKVTKTKKTELLFLALFLRVLKIGGRCACIVPDGVLFGSTGGHK
                     SIRKEIVDNHKLEAIISMPSGVFKPYAGVSTAIMIFTKTGTGGTDKVWFYDMKADGYS
                     LDDKRNEIKDSDIEDIIKRFDNLDGEVDRKRTEQSFFVDVEEIRENGYDLSINKYKEV
                     VYEEVVYDAPSVIIGRVRELEKEIVDGLEELERMLEV"
     gene            complement(46827..47696)
                     /gene="gatY"
                     /locus_tag="PC512_000268"
     CDS             complement(46827..47696)
                     /gene="gatY"
                     /locus_tag="PC512_000268"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatY"
                     /protein_id="HDF2440048.1"
                     /translation="MALVTTKQILLDAQEGHYAVGAFNVENMEMVMAVIEAAEELKSP
                     VILQTTPSTIKYAGLDYYLANVKVASEKASVPVAMHLDHGSSFGLAMQALRVGYTSIM
                     IDGSHESYEDNISISKSVVDACMPSDIPVEAELGKVGGKEDDLDGGDGGAYTDPLEAK
                     EFVERTGVSSLAVAIGTAHGLYKGEPKLDLDRLSEIREVVSVPLVLHGGSGIPDEVIK
                     ESIKRGICKVNYATELRIAYSNGVKDVLNSDPEVIDPKKYGKKGLESVKDFVKSRMEV
                     CGCVGKAIEIVKC"
     gene            complement(47716..49632)
                     /locus_tag="PC512_000269"
     CDS             complement(47716..49632)
                     /locus_tag="PC512_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIABC"
                     /protein_id="HDF2440049.1"
                     /translation="MGKKMILGVTGCPTGIAHTFMAEEALKNSARELGCDIKVETNGA
                     IGVENKLTAKDIEMADAIIVACDKNVDMDRFNGKPVIEVPVKEGIHKANELIQRCIDG
                     KVAIRKGNLSSSKIAEEGNLSFGQKLYKDLMNGVSHMLPLVVAGGVLTAISFLWGIYS
                     FDPNSEQYNQIAATLKSVGGYSMNLMVPVLAAFIAQSISGRAGMLAGLVGGMISFDTG
                     SGFLGGIISGFLAGYLVKLFVHLLRKLPRQLEGLKSIFIIPIVSVGLVGVAMLLLGGP
                     CSALNNAMMNFLSGLQNSSPIILGIVIGCMSAFDMGGPVNKAAYVTGTMLLGQGNYLF
                     MAGVSAACITPPLVIAIASTLFKNRFTEEDRAAGLINYILGSTHITEGAIPFAAKNPL
                     KVLPVLMIASSISSILTYIMKIEVPAPHGGFLVLGLVNKPLLWVGCIFVGSLVGAVLY
                     MMVTPKVVNEKNTIENTNVTKDEHKNESAESENVSNNISLYSEETVILDVKGKNKTDV
                     IDEMIGILDKSSVLLDKKKFKEEILKREEISSTGFGMGIAIPHAKTDAVKVPRVAVGL
                     SKEGFDFESEDGSLAHIIFMIAATDNGDNLHLKTLSQLSSKLMNEEFLNELLNSKTSR
                     EIVSKLNNEEIKSV"
     gene            complement(49635..50555)
                     /locus_tag="PC512_000270"
     CDS             complement(49635..50555)
                     /locus_tag="PC512_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase family hexose kinase"
                     /protein_id="HDF2440050.1"
                     /translation="MIYTLTTNPAIDMNISTNGIKRKLVNRTSNAVYSPNGKGLNVTF
                     VLGHYGIESKILGFFGGFSGKYIVEESEKRGFDVLPTWVEDTTRINIFLNDGSDEFKF
                     VNSGSYVNEKQKLDMLDKIQSLEDISYLSISGSLPPGIDDNYYEDIFKICENKSIKTI
                     LDISSPKLKELLQYNPYLIKPNDEEIKDIFGIIVRDEEDIKDVLKLLHLKGAQNILLT
                     LGEKGSYFYNGKSIYYASAQPVTVVSSACAGDSALAAFLSIWLENPEHIEEALKRSAA
                     TGASVAESNGIGNLENVEDYIKNIRVRKVV"
     gene            complement(50657..51409)
                     /locus_tag="PC512_000271"
     CDS             complement(50657..51409)
                     /locus_tag="PC512_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF2440051.1"
                     /translation="MIIELNKSNSENLTKTELEIIKFINENESILPELSIVEIAHETY
                     SSPATVSRAIRKCGLNGFNELRYRLTVKDENDDIQNMGDIINKSFIEAQRVIEQISLT
                     TLINIIKTVNKSSKIYILARGLTEYVAKEFSLKLQLLDFNVVFINDPNIMKIKSKSIK
                     KDELIIIFSLNGNTIELVESAQNANLVGAKVITCCCSESAKLIKYSDLYIVGYKHEHI
                     SISEYEVSSRLPLYIISRIIIDYMVRYNNSEN"
     gene            complement(51801..53246)
                     /locus_tag="PC512_000272"
     CDS             complement(51801..53246)
                     /locus_tag="PC512_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDF2440052.1"
                     /translation="MIKLGKFPKGFLWGGAVAANQLEGAWNEGGKGWCLADVHMYDKD
                     RDISKPYESDMTIERIKFAMKDNNGYYPKRSGIDFYHTYKEDLKLLKELGLKCFRFSI
                     NWARIFPNGDDLEPNEEGLKFYDNLINEVIDNGMEPIVTLLHYETPLNLVLKYKGWSN
                     RKVVDFFVRYAELILNRYKNKVKYWIVINQINLIHYESFNSVAFCVDQVDNVEETRYQ
                     AIHHQFIATALTKKLGKEINSDMMIGMMMADCTSYPEDCDPENVVFALKRNRLQYFFT
                     DVSFRGEYPVYIKRFFKENNINIVMEEGDDKILKENTMDFLALSYYYSTTVSASKNTM
                     NPTDNIKNPYLKANPWGWAIDPKGLYNTLSQYYDRYQKPIMIAENGFGMHDKFEDGKV
                     HDSYRIDYLGKHIEQIGEAIADGTEILAYCMWSPIDIVSCSSQEMEKRYGFIYVDIDN
                     NGNGSKKRYKKDSFYWYQNVIRTNGEELKEK"
     gene            complement(53268..53621)
                     /locus_tag="PC512_000273"
     CDS             complement(53268..53621)
                     /locus_tag="PC512_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDF2440053.1"
                     /translation="MTIEEHIIDEELVEVAMQIILRAGEARTEIKHALNDLEKFDYRN
                     ADLKLAKAKGFMTEAHRAQTKIIQGEAGGEKRAHSLLFAHAQDTLMTIFSELNITMSL
                     VGIVKSIEYKVNNSK"
     gene            complement(53650..54897)
                     /locus_tag="PC512_000274"
     CDS             complement(53650..54897)
                     /locus_tag="PC512_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2440054.1"
                     /translation="MGRVFMNKFIDFLSEKFTPVVNNMTKNIWVQSVQSTIMKVLPMV
                     FVGSLVTIVSVLKNYISFLPDLSPINQYTFGLLGLFIAFLLPMEIMKNKKFESMSVVA
                     GLAGAGLMLMMIRPEITNEGAIFNFNRFGGEGMLVSLVAGLFSGLIMSLFGSFSFFGE
                     DSALPDFVSKWFDNMLPITVIMFVGWGLIYGLNFDMFEIIVRVFKPVSDIAQTLPGFV
                     LLNFLVVFIYSLGISGWVLSPITYSIQLGAIAANAAAVASGGVATNIYVYEVIQTGWI
                     TLGGLGATLPLVIMMCLSRVGRIKAIGRACIVPSIMNINEPVIFGAPVAWNPFLMLPM
                     WIGTVVISITTYLSMSMGFVTIPSKVFNLWYVPFGISTFTVNQDVRGLIVLAINIVLL
                     FMIWYPFFKAYEKEEIKLESQEV"
     gene            complement(54905..55222)
                     /locus_tag="PC512_000275"
     CDS             complement(54905..55222)
                     /locus_tag="PC512_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2440055.1"
                     /translation="MKNIRVLLACGSGASTGFMATSMRKSAKKKGIEADIKARSESEI
                     DKYLSEIDCLLLGPHLDYMKEEIQQKANEYNVPVACISKTAYGRLDGAKALEEALELI
                     SNK"
     gene            55464..57377
                     /locus_tag="PC512_000276"
     CDS             55464..57377
                     /locus_tag="PC512_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2440056.1"
                     /translation="MKTSKKELFLNFIKTQHDWIDSSTLANYLNVSTRSIRKYVNEIN
                     SNGEFILSSKKGYKVNLNNNCQTKVDSSENISPDNRLNLILKELIVNSNGINIFDLSE
                     DLFVSPATIEGDIVKANKFIGSYNLKIKQSKFLLKLIGNESAKRKLMSSIIFKETGSD
                     FLSLFDVQKIYQEYNLTKLKENIIYILKKYNLFINEYAINNILLHLMITIDRIKKNNY
                     IESVEVVNYIDNNNDISISRDISNFLESEYNITLTSAELYYLVFQLTNKTTVLNYHEM
                     DTKSLPNYIDEHFVKLTKKIIKNVYDLYFIDLSDDEFVVKFTLHVKNLISRAKNNQVL
                     RNQIPQKLKDSYPLIYDISVYICNQIQILENIEIDEDEISYISLHVGSFFDRQKLLED
                     KILCALITPNYYDLQFKIVRDLEKRFNESIEIIQIFSDTHNLDFDNKVDMVITTLPIS
                     DRCPIPFVYVNPYLNRKDYDNIQSKFIQIKDRKNILTVQNHLEMYFSESLFMKNIYLD
                     SAKDYIRFMGNILYENKYVKPNYIDDVLIREKMSSTAFNNNVAIPHSMKMDALKTGVC
                     LIVNDKPVKWGEEKVQIIAMIPINEKEKEKFNYIFESFIEILSEWNNVKELTKADNYS
                     SFMNRIAYLIQNI"
     gene            complement(57500..58654)
                     /locus_tag="PC512_000277"
     CDS             complement(57500..58654)
                     /locus_tag="PC512_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HDF2440057.1"
                     /translation="MKILISIDSLKGSLSSIEAGNAIKKGILKVKEDAQVKILPLADG
                     GEGTVDALVQGMNGKKDTIEVTGPIAKKVDATYGLLKNTSTAIIEIAQASGLTLVPTE
                     LRNPLYTTTYGVGEIIKEAINKGYRNFIVGIGGSATNDAGIGMLQALGFEFYDENNKL
                     VGLGGKVLNEIRHIKIENRLKELDECKFKIACDVNNPLFGKNGAAYIYGSQKGATSEI
                     IEELDNGLRNFSKVVKNYLSKDVANVEGAGAAGGLGFAFLAFLNSKLESGIKIILEEI
                     KLEEELKDADFVITGEGRLDNQTAMGKAPIGVAKLAKKYGVKVIGLAGATTEDAVKCN
                     EEGIDAYFSIVNRAMTIEEAMDKATASENMTATTTQIFNLITSIQQSKNM"
     gene            complement(58914..61529)
                     /gene="mngB"
                     /locus_tag="PC512_000278"
     CDS             complement(58914..61529)
                     /gene="mngB"
                     /locus_tag="PC512_000278"
                     /EC_number="3.2.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosylglycerate hydrolase"
                     /protein_id="HDF2440058.1"
                     /translation="MKKNVHIVPHMHWDREWYFSTEESRILLVNNMEEIMDMLENNHN
                     YPYYVMDGQTAILEDYLAVKPECKERIKKLVQEGRLIIGPWYTQTDEMVVGGESILRN
                     LLYGIKDCDEFGEYMKIGYLPDSFGQSAQMPQILNGFDIKYSMFWRGCSERKGTNKTE
                     FNWKSDDGSSVLVQILPLGYAIGKYLPMNEDELRTRMDKYLPVLDKGATTDHIILPNG
                     HDQMPIQKNIFEVIYKLKECYPERKFFLSRYENIFKELEKNEDIDTIKGEFLDGKYMR
                     VHRSIFSTRMDIKSANARIESKITNILEPLASIAYSLGFEYHHGLIELIWKEIMKNHA
                     HDSIGCCCSDKVHHEIMNRFFLAEEKVDQLITFYKRRIVDAMSCEMALDKLVAFNLMP
                     YDRNEIVSAQVITKMKAFEIFDKDNNKLDFEVVHKEVIDAGLIDRQIVHYGNYDSFMV
                     YTINFKDKIPAMGYKAYMIKEVEHMLEKAYEVCDMVDNDFYTIQVNENGTLKIFDKKL
                     NKTFENVLLMENGGDEGDEYDFSPLPNEKLIFNDNIVANSTIKKNRFNNEIKINYRLK
                     VPKDIQARKNNRADSFIDFDIVINVPNDKAIIDVVFNINNQARDCRVRTYIPTNIASK
                     FSVSDNQFGHIKRSVYDDAMEVWQQEEWSERPDSIYPMLTFVGLSDKEHGVAVLTNST
                     REFEIVGEKFDTIAITLFRSVGFLGKEEMARRPGRPSGIKLPTPDSQMIGDIKIDLAI
                     VTHEKSTLEANVANMAKEYLTKIQTYNKMPYNAMKLNQSEIEVDYSYSLLKETNKDLV
                     LSVVKKAEKQEALVVRFYNSKEETKSANIVFNKNIKTAKWINLNEKELESISIDNNSV
                     NVECLMNQVKTILVK"
     gene            complement(61673..63598)
                     /gene="mngA"
                     /locus_tag="PC512_000279"
     CDS             complement(61673..63598)
                     /gene="mngA"
                     /locus_tag="PC512_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS 2-O-a-mannosyl-D-glycerate transporter
                     subunit IIABC"
                     /protein_id="HDF2440059.1"
                     /translation="MEFKKITNENLVFLKQKIKTKKDAIKFLARKLYDEGKLTSYEEY
                     LEAVMYRETLSPTGFERGLAIPHGKSKSVKEAAFAAMTLETPIENWESVDPNNKVEII
                     FLIAVPENEGGNTHIQILSELVTRLSNEDYMNMLLNSKTKKELFNNLDIKEKKEQIKE
                     EIRIQNESKKIILAITACPAGIAHTYMSAEALIKAGKEIGVDVYVEKQGANGMVDPHT
                     PDIIKRADAIIYATDVAPKNTERFEHLPNIKTSVAAPLKRAKEIIYEALEVAQKQGKG
                     DYIEKSSDISYCEKSSWKKDVKSAILTGVSHIIPLIVAGGMILAFAVLASQAFGLQEL
                     YNQEGSWLWQLRKLSGGMLGTLMVPVLSAYMSYSLAEKPGLGPGFAAGLAADLIGSGF
                     LGGMLGGLLAGYIVKFLKKNIPAKGTLAGFVSFWVYPVVGSLVVGLLMLFVVGKPVAA
                     LNNGLINWLNGMTGVNAILLGAIIGAMVSFDLGGPINKAAYTFAIGAIASGNFIPYAI
                     FASVKMVSAFGVTIATVLGRDLFSESEKEIGKQTWILGLAGITEGAIPFMIEDPIRVI
                     PSLVAGSAITGSIVAFFNIGLQVPGAGIFSLALLEGSMSGFIIASIWFFAAVLGAIIS
                     AVLLIITRKQKNQRKIH"
     gene            complement(63728..64453)
                     /locus_tag="PC512_000280"
     CDS             complement(63728..64453)
                     /locus_tag="PC512_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF2440060.1"
                     /translation="MEFYERAKKYEYKFTDTEDMIIEYMRKNKEEIVKLSIQSLADKF
                     FTVPNTIVRLCKKMEYDGFSQLKNNLKEELKNEDKEPKNGFESDIKKTLELIDYEKIN
                     KVADIIQKSRSIIVYGIGQNIPLCEILVKEIRGGHDNITYYSQRHEVLHDIGKLGEQD
                     MFFALSLSGETKEVIEVAKTAVNKGCKVVALTHICENQLQQIADISLYCYSTIKQVNG
                     YNISDKVPIMMIMRAIIEQYWLR"
     gene            complement(64716..65486)
                     /locus_tag="PC512_000281"
     CDS             complement(64716..65486)
                     /locus_tag="PC512_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ChbG/HpnK family deacetylase"
                     /protein_id="HDF2440061.1"
                     /translation="MKKLVVRADDIGYSEGVTLGIISSYKNGIVTSAGIMVNMPFSRQ
                     AIEMVKNDDVCFGLHVNLVIGEPCCKEHIKIKNLLDEGGKFVSSKIRRTQLLTGKEVF
                     NYEEVYEEVCAQIETYKLYMSKLPEYIDIHGIEEDVSISAMCDAAKEYGIPSCPYYLD
                     SCISMPSKYPQNDFYKLNKSFVKLFEEKYINLDKDITLMVTHPGFIDYSLIKSSSLIQ
                     ERVYEHAMLCDKEVKMWLKRNNIELVDFKDIFKSNNYI"
     gene            complement(65488..66915)
                     /locus_tag="PC512_000282"
     CDS             complement(65488..66915)
                     /locus_tag="PC512_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDF2440062.1"
                     /translation="MMQQLSLLGKTMLVPIAVMPAAGILGLLFGPNMLNVPAISNISN
                     IVFSNVDYLFLLGAASAYSKSKDKTSVMVAAVVAYMIFKSNLELLNDTLNAGVFGGII
                     VGACIAWTYNKTYKVKVPAFLSFFAGEKCVITLSPVVALILSYIFSLLWIYPQAAMNQ
                     FGFWLGGAGAIGIFLFLFCNRALIPTGLHQVLNAYILFEMGEYTTSTGEVIRGEIPRF
                     MAGDPNAGFFWTGFYIIMMFSIPAISYAIYKTAQDKKKQEVKGAMTAGALTSFMATVT
                     EPIEFSFLFASPKLYIIHSFYSGLGGVVLYLLGVRLGSFNGASIIDYVLSFSYGDKAW
                     LVIPVGVVFFVLYYVTFKYIIIKDNVQTPGREVEIEIGDKVSEKEKNLKLSHGNFSYM
                     AKQIIKNCGGYENIVTLNNCMTRLRLEVKDATILNDDNIKKTGAKGVIKLSNTSVQII
                     IGTDVVKVKDEMEMQLDELRKQADA"
     gene            67306..68028
                     /locus_tag="PC512_000283"
     CDS             67306..68028
                     /locus_tag="PC512_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2440063.1"
                     /translation="MAKNKFSEIYEVLKEEILDGKYTSNMMLPTELQLIERFSCSRNT
                     VRRAISQLNTEGYVQSIKGKGVVVLENSCSNDFFLNMHNFKGVESIVEDKKVNTATSV
                     LHFSKILIDNKLSKKTGFKVGSEVYYLHRLRYIDNIPKILDINYFLCSIVKDLDVSIA
                     QGSIYKYIEECLGTKIVSSRKIFKIEKATELELKTLPLNDYNCVGVIKNSVYTDDGKL
                     FEYTESKHTPETFVFMDVTQRY"
     gene            68225..69892
                     /locus_tag="PC512_000284"
     CDS             68225..69892
                     /locus_tag="PC512_000284"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HDF2440064.1"
                     /translation="MKNWWKKATVYQIYPKSFKDSNNDGIGDINGIIEKLDYLYYLGV
                     DLLWLTPMYVSPQRDNGYDIEDYYNIDPKYGTMSDFEKLLKEAHKRDIKIMMDMVLNH
                     TSTEHKWFKESKKSKDNPYRDYYFWKDAKPDGSVPNNWISRFSGTAWKYDETTNQYYL
                     HLFEETQADLNWENEKVREECYKILEFWADKGIDGFRLDVVNLLSKTPGLPDDPITGP
                     KGDGRTHYADGPRIHEYLHNMNQKVFKPKNIVTVGEMSSTTPEECINYTRENREELSM
                     VFSFHHMKTDYKGGAKWTNEMFSLDKLKKAQSDFQYKMYEGKGWNALFYSNHDQPRAL
                     SRFGDDRFFRQESAKMLAITLFGLQGTTYIYQGEEIGMTNAYFTKIDEYDDAESKNAY
                     YHMIKSGIDEKEALLILQQKSRDNARTPMQWDNTIYKGFSNHKPWLKVNNDNISVENE
                     LNDSRSVFYTYQRLIKYRKQYDIFTEGTYRLLDENHKNLFVYEREYKNQNLLVISNFT
                     HDNVVYKLPETYLNKLNYTILETNYTRDIIENKMEIKPYESIMIYYK"
     gene            complement(69988..71307)
                     /locus_tag="PC512_000285"
     CDS             complement(69988..71307)
                     /locus_tag="PC512_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDF2440065.1"
                     /translation="MEKGIKLGFWSIVLLGINAIIGSGIFGLPGDAYTDIGPASILVL
                     VFCMLLAVSIALCFAEAGSWFDTDGGPYLYAKEAFGDFVGFEVGFMKWIVSMIAWATM
                     ANFFAVTLSSVWPQAAEPLIKNIIIGILVVGLGIINFMGMKQSKHLNNIMTIGKLLPI
                     VLFIAVGLFFIKGSNFTPFVIIQKGQSASSAFVAVSITLFYAFTGFESLAVAAKDMEN
                     PKKNVPKALVMVMFVVSVIYMLILGISIGVLGNGLAGSATPVADAAIKMLGPIGGYII
                     TIGTIVSVGGINIASSIFTPRSAAALVEQGLMPKSIRQTNKNGAPYIAIIVSVIGTLL
                     IAWSGSFTTLSQISVVSRFIQYIPTCLAVLILRKKYAGKDVNFRIPGGAIIPIFAVII
                     SILLLIKAGIDEPMKIVWGLGGMIIVVPIYFYMTKVYSKKYNDVEVK"
     gene            complement(71348..72094)
                     /locus_tag="PC512_000286"
     CDS             complement(71348..72094)
                     /locus_tag="PC512_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HDF2440066.1"
                     /translation="MKKLAKKKYPIIGISGNLLIDEGGMFPGYERAYVNNDYIQSVVM
                     CKAIPYIVPIVYDDEIIKEQVSNIDALILSGGQDVNPLIWKEEPHNKLGAISPKRDSF
                     DMKLLKHALDMKKPVLGICRGEQIINVTEGGSLYQDLSLIEGAYIKHNQQHLSNVPTH
                     TVQIKEGTKLYEILGEKEVLVNSFHHLVVNKVAPGYIVSATSKDGLIEAIEKEGSEFV
                     IGIQWHPEMMTRDYDNMKKIFMAIVKEASK"
     gene            complement(72338..74347)
                     /locus_tag="PC512_000287"
     CDS             complement(72338..74347)
                     /locus_tag="PC512_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2440067.1"
                     /translation="MKTIAVVTDGLSKLECFLNKNLEMIFKDKVMIKNYYLNKITEKE
                     LIKDDIILVMIDDRVLKIKKYVEDVSKIITINRSIKQKDIYKLFSLPEGIDVLVVNDN
                     KHTVLETISNLYNIGINHLNFIPYNPNEEYRNIKIAITPGESSLVPKYIEEVIDLGHR
                     YIDSSTFIQIIAKLKLDDKEITERLIKYTDEIISLYSGINTKYKELTIKADELNSIIN
                     LSNLGMAMVSDKGNIIICNNSLRDILDIQSNIIGKNIDELENENIKKIFSLSKAHDEV
                     IKFNNKYLNVNKYNIESFGRVTGYYFCIQEITYIRKLEQNLSKKLREKGQVARYTFDD
                     IKTVSTKMERTKKLGMKIAESDYTILITGESGTGKELMAQSIHNASPRHSQPFIAINC
                     AAMPENLLESELFGYEEGAFTGALKGGKKGLFEQANNGTIFLDEIGDMPIYLQSKLLR
                     VLQENQVMRVGGENVIDIDVRVIAATNKNLLEMIKGDRFRADLYYRINVLPINIPPLR
                     ERKEDIEVMLKHFMKRKRAISQDVQDIINAYEWPGNIRELKNTAMYINIMSSEDVILI
                     NDLPHNLLNITEDFSKEISILKDRTSIEKVKLVMECLKNANNLNKNIGRNGIVNSINE
                     LGYNITEGEVRGILNMLKELDLIICESGRKGSELNRRGKNILNSI"
     gene            complement(74741..76174)
                     /locus_tag="PC512_000288"
     CDS             complement(74741..76174)
                     /locus_tag="PC512_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDF2440068.1"
                     /translation="MALRKDFLWGGATAANQCEGAWNLDGKGPSCSDMCTGGSQKVSK
                     RITRVIEKGTFYPSHEAIDFYHRYKEDIALFAEMGFKVFRFSIAWTRIFPTGMEKEPN
                     EAGLKFYENVIDECLKYNIEPLITISHYEIPFAITEKYNGWVSRDVIDLYMNYCETIF
                     KRYKGKVKYWLTFNEINSATMPMGGYLSQGILNEGTTDFINQVDIPQLRFQGLHHQFV
                     ASAKAVKLAHEIDSNYQVGCMQIFATMYPYTCNPDDAVKTQRDSRVMNYFCGDVQVRG
                     EYPTYMNRYFGENNIEIKMEKGDLEILKEGCVDFYTFSYYMSTCVSSDSKEDNTSGNI
                     LGGVKNPYLKSSEWGWQIDPEGLRYALNEIYDRYRIPMMVVENGLGAYDKKESNGVIN
                     DDYRIEYLKAHIEQMKEAVEDGVDLFGYTPWGCIDLVSASTGEMAKRYGFIYVDKYDD
                     GSGDLSRIKKKSFDWYKQVIESNGERL"
     gene            complement(76261..78177)
                     /locus_tag="PC512_000289"
     CDS             complement(76261..78177)
                     /locus_tag="PC512_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2440069.1"
                     /translation="MRKYEQLSKEIIANVGGKDNISSLSHCITRLRFKLKDESIANDD
                     VLKKMDGIVTVMKSAGQYQVVIGNHVPDVYEVVCDLAGLGGDTIDNSDSDAPKGLLNK
                     FIDIISGVFQPILGVLCAAGMIKGFNAVFTALGLYGETDGAYIMLNAIGDAMFQYMPI
                     ILGYTAAKKFKLKPFIGMLIGAVLCYSGIQLDTLASTGQPLYNLFTGTIFESPVYITF
                     LGLPVIAMNYTSTVVPVILIVLLAAKLEKVFAKIIPDVVKNFFVPMAVLLVSLPLGFM
                     VIGPIATYASNIVGNGFLALFNFSPILCGALTGLLWQVLVIFGLHWGLVPIAMSNLMT
                     MGFDTILVGVFVPSFAQTAVVAAMYFKLKDKKIKELCIPAVISGICGVTEPAIYGITL
                     PRKTPFIYSCVGGAVAGAVMGIMNVKSYVMGGLGIFGIPNYINPTTGDMKGVYATIIA
                     IIVAIVVGFVLTLFFWKDDAIVEISKDDNGQGVIEKNKREVVYSPIKGEVKALEQIQD
                     AAFSTGILGKGVAITPKEGKVVAPFDGTVMTLFPTKHAIGIISDNGCELLIHIGLNTI
                     QLEGKYFKSFVNQGDKIKKGQTLITFDIESISKEGYCLETPVVVTNYSDYVDIVENTQ
                     KHVNNSQKLITVLA"
     gene            complement(78251..79111)
                     /locus_tag="PC512_000290"
     CDS             complement(78251..79111)
                     /locus_tag="PC512_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF2440070.1"
                     /translation="MIIEKILNNNVIITTDENHKEIVVMGRGLAYKKRTGEHISKDKI
                     DKIFKLSDPNISDKFKELIADIPIRYMELSDEIILYAKEKLGKRLNDSIYISLTDHMY
                     TAIERAREGVSVKNVLLWDIKRFYKSEFKIGLEALDYIEKKFEIRLSEDEAGFIALHI
                     VNAQMDQSIKTIYEITQIIQEISNMVKYHYRIVFDEDSVYYHRFITHLKYFAERIVSN
                     NLHENNEDDLLNVIKVKYKNAYKFIEKLDEFIHKKYNYDLTDEEKLYLTIHVERVVSK
                     SIKSDINPNN"
     gene            complement(79462..80649)
                     /locus_tag="PC512_000291"
     CDS             complement(79462..80649)
                     /locus_tag="PC512_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDF2440071.1"
                     /translation="MIESIKKRAYEIENELGKEIEEVCNFIFNNPELGEEEYISSKYL
                     VEKMKEYGFDTVYPYCNMETAFRAELGDNDGPTIAFLAEYDALPGYGENKEPAHACGH
                     NWIAASTLGACIVLSKLKENFKGKIVLIGTPAEETTGGKCDLVKAGAFDDVDVSYQMH
                     IEAFNNINCKALAIDSLEFSFEGVSAHAASHPHMGVNALDAVQLTFAGINALRQHVKS
                     DVRIHGIVSNGGEAPNIVPEKAACKFFVRAAERSYLDEVTKKVINCAKGAELMTGAKL
                     SYRYFENSFDNIINNKVLQKITKNNLIEAGITDILEGKDGPVGSTDIGNVSQVCPTMY
                     TEIALDISPMVYVHEKEFLNYANSEEAYDKLHKAVKAMVGCALEIYLEDGLLDEIKKN
                     HLN"
     gene            complement(80663..82054)
                     /locus_tag="PC512_000292"
     CDS             complement(80663..82054)
                     /locus_tag="PC512_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HDF2440072.1"
                     /translation="MSSLKKKKFTMPQTLTIIFLLIVLMAILTWIVPSGNFERVDIDG
                     RSVVVAGTYEKAPSNPQGITDVFTAPINGFIDAAEVVGFVLIVGGAFGIVNKTGAIEA
                     VIAHTVNKMKKFQFLIIPISMILFGLGGTTFGMSEETLPFYMIFIPLMTSMGYDSLTA
                     VATVFIGATAGFGAATTNPFSVGIAQALSQIAPGSGIEFRVVMFIIYMAISIGFVMMY
                     ANKVKKDPKKSLVHDISLNQESMVNSDTNIKEFTKREAMVIAIFTIGMAIMIYGVLKL
                     GWYITEIAMIFTAIGIISGIASGLKQDDIVNSFISGAGDLMTAGLCIAFARGIVIIAE
                     NGFIIDTILNSAANLLNGLPKTIFINLTFLIEGLIAFLIPSASGLASLTIPVLAPLGD
                     LVDVSRQMIVTAYQFGIGVTNLITPTSGVLMGALAVANIPWSKWVRFVIPLMVVLTIL
                     VMAFLTIGLYLGF"
     gene            complement(82649..84349)
                     /locus_tag="PC512_000293"
     CDS             complement(82649..84349)
                     /locus_tag="PC512_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDF2440073.1"
                     /translation="MHYIAWHFNKNGGNNTMKDKLQVLSGAMMIPVILLVVAGVFIGL
                     GSAFANMENVSALGLSGLIKEGSFINVFFKVINDLGFMVMRYLPIFFVTGIAFGLSKK
                     EKGWGALGGIVLFIGMHTVISTLLAANGINSDTVTAEAFMASGLGEAEAYSRSSLYGS
                     FLGIFSYDCSIFGAIIAGFVASAVHNKFVDIELPSALSFFSGPRFSMIMMFIASIVLG
                     TAMYFIWPPVGLALSKLGNWIGSSGLLGTFTFGAMDKALLPFGIHHLIAFPIEYTRVG
                     GTMEVGGAIYEGVNNIRLAQMGDPDTLSYITRNFTTGRLLIHFAILPAAALAMYKLAD
                     NANKKKAISILIPAIVTAMLVGVTEPIEYTFLFVAPLLYFVAYVPLAGLTYVFTEMFN
                     VSIMGESFRNMFPNLLQPQKVDALPLLFLIPIFFIVTYIIFTWAIKKFDIKTPGRSSE
                     EVKLYSKKEYRERQSVDAGKTAYNNAVEEEVDDKDTKLVHSIIEGLGGSNNIKNVTNC
                     ATRLRVELNSIDGFYEDGFWVNELGASGVVKKKNSVQVIFGPRVITIASKLKAVLGVD
                     "
     gene            complement(84321..85724)
                     /locus_tag="PC512_000294"
     CDS             complement(84321..85724)
                     /locus_tag="PC512_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDF2440074.1"
                     /translation="MIVNKELIIDYLKSNQENIINDIRSLVEIPSIRDESTTDINQPF
                     GIEIRNAFDKLIQIAKDKDFVVKDFDGYAIHIEYGEGEEVVGVLNHIDVVPIYNKELW
                     KSKPFKVCQKDNYLYGRGVNDNKGPLIGILYALLFLRELNEKPKRKIRLIVGGAEETT
                     WECMEHYFSVNEQPKFAFSPDGNFPIVNGEKGILYFNLRKKIDKDKFRNHNLVDIKSN
                     KEDGFVCDKIEAVFKTNDKKDLVESLAYYTEIEELEEGKVLVRYTGERALSRNPHRSY
                     NCAFSLAKDLEKIKKLNDKGVIIRDILNSYFTDDNHGKKLGIYKEDVDMGVSTICIMS
                     IFLEKNELNMKIDFRYPKGISWEFITNRINEIGKKENLIVDIYKDLKLLYVKPDSELI
                     NKLSNAYKQGFGKEAELFTKGAASYARVLKNGVAFGPTIEGDNPNSHQANENISIDTL
                     YKAIEVYIYALYSLAFQ"
     gene            complement(85988..86479)
                     /locus_tag="PC512_000295"
     CDS             complement(85988..86479)
                     /locus_tag="PC512_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2440075.1"
                     /translation="MFNIFKKKENKIEKIYSPFKGNLVNLEDVPDAVFAQKMMGDGVA
                     IIPSEGKLYSPVDGEIVNVFDTKHAIMIKSNDNTNILIHVGLETMSLEGKPFDVKVKA
                     GDKVKAKDLIMEVDLDFITSNDLNIITPVVIMDDADSVKRTVKDRIEPGNVDINSIIM
                     EVE"
     gene            complement(86505..87317)
                     /locus_tag="PC512_000296"
     CDS             complement(86505..87317)
                     /locus_tag="PC512_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDF2440076.1"
                     /translation="MRYKLICTDMDGTLMGKGFEVSEENIKALKEVMEKGIKVALVTG
                     RPYNAMKYFTSVLGDDIYIISTNGTYFKLLGYEYKKVLSKEALKKIYTIGEKYNLSKH
                     FKGCKIVISNNEIGEEHPYRLINSKNKEEDRIEIIENASCETLLEKADNEILKCILFS
                     ENVDSLREAKEEFKKQEDLEVVSSGKINFEVMSKGTSKGIAVKKFCDILGIDSKEVIC
                     IGDNENDISMIKFAGLGIAMGNATDEVKSMADFVTDTNVNDGVAKALRKILS"
     gene            complement(87330..88481)
                     /locus_tag="PC512_000297"
     CDS             complement(87330..88481)
                     /locus_tag="PC512_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HDF2440077.1"
                     /translation="MINFYQPSRINFGQGTLSELPRIIGKYGKKCLLVTTPNVEPLDK
                     LYKRVTLNLIEKGIEVVHFDRVEPNPTVELINEGFELAKKESVDVVLAVGGGSSIDTA
                     KVLALTFGLEKIDWDYMFSTYTNPFKIYDKVSEKELPLIAVSTTSGTGSQVTQAAVIS
                     RGSEKNTIFHQNCFSKECIVDPELMLTLPERITASTAFDAFTHAFESYINPNANDFTE
                     IMSEKSMELVINYLPKVMEDKNNIEYRTKLAVADTLGGSSLANAGAAAPHPLSEIIGG
                     VTHIPHGEALAIVFPKFAEKFYKDNIEKFAKVARMLNQELEKVEDDEAAKTLGNEIES
                     FLKRVGLKTKMSEFNVTKEQLEQITSCPVLGFLPFGKKEDLVEILEKSY"
     gene            88751..89392
                     /locus_tag="PC512_000298"
     CDS             88751..89392
                     /locus_tag="PC512_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase"
                     /protein_id="HDF2440078.1"
                     /translation="MKYLIDSANLDEIQKCLKYGFKGITANPSMYLKEKVNFHEFIET
                     CANLNPEILTAEVIGNNLYELINSCDKILNINKNTIIKINFSEVGLELINILNSKGVK
                     TACTLIFNVNQASLAINAGADYLFPFIGRNDENGNDGIKNLTEICNLISINGYNTKVV
                     AASIKNVFHLTQASLCGCDYAAVTYDLFKKASFNQLTIDGANTFERDWSKVNK"
     gene            89418..90962
                     /locus_tag="PC512_000299"
     CDS             89418..90962
                     /locus_tag="PC512_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF2440079.1"
                     /translation="MNKRLLDIAELLLNSSDYITVDTIAEELKVSNKTIRNDLVILDE
                     WLLEFNLSLDKKTGSGVIILGNEDIKLKVIRDINDKSNCIYAYSPEDRKRYILSKLFI
                     KNSKFRIRDICNELHVSRATVHKDLVVIQNFLQNFKVTLVRKTNNGVYLEGKEKDIRK
                     AIFELATVNKSYTELKEILFSKSNECKDTPSTKIFKELFNYDFEKLSQITLHTLQVEK
                     SNLSDEYYINFLIHIAICIKRISIKRYINLSEGFFRELLEHEYFEKSKILCANLSEAF
                     DVEFIDEEVCYILLHIEGLLKSIKKTTTLEPLKNEEITEYNLSEAIAVHWGSILNLNL
                     KDDLILIKSLANHLKSVLHRINYGFTITNPILNDIKRTFPYTYKAAKESNTVIKQLMN
                     YEVNDDEIGYLALYLISAIDRSKSPLNTILICHCSDGVSNLLVQKLSFEFNQINIVKS
                     IPLSSISFTNFDDVDLILTTAPVDFEHNAELININALLSKNDISRLSTIIKKLYSEKN
                     KILSYK"
     gene            complement(91162..91788)
                     /locus_tag="PC512_000300"
     CDS             complement(91162..91788)
                     /locus_tag="PC512_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDF2440080.1"
                     /translation="MKKEMIKDYLLITISAFLMALAVNFFFAEHTLAPGGITGLSVVL
                     STFLSMPVENISLGISMPLLVMGLLFLGKGFGIKTLYITLMGPLFLKVIPQTHITDNL
                     LVAGVIGGLLVGTAIGIAIIRGCSTGGTDLVAMLINKVIKFLKLPVILFMLDGFIIVA
                     SGIISKNFMISIYSLISLLLIIKTIGFVTTKFGKNTEEINNINNACAQ"
     gene            complement(91923..92639)
                     /locus_tag="PC512_000301"
     CDS             complement(91923..92639)
                     /locus_tag="PC512_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentose-5-phosphate 3-epimerase"
                     /protein_id="HDF2440081.1"
                     /translation="MKHIKIAAGLAHVNYGHISAVVKEAMDAGVDYVHSDAADMHDLK
                     NMQLMGGHQIIEAIRPVTDKPIECHIYTRDCDRLFIEKIAAAGCNLLIIPAEHFLGAP
                     LAYIINYCREFGMKVGLTIGCYTPLCFVDEAIYDIDRLQIVVHGVDETDGKDNWGWRK
                     SAVDLVKRARKMIDEKNPKCELAIDGGLRADNMEPLIECNPDVVILSSAIFKDKDGIT
                     AGVKNCRKAIDKAATKFGLE"
     gene            93065..94279
                     /locus_tag="PC512_000302"
     CDS             93065..94279
                     /locus_tag="PC512_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HDF2440082.1"
                     /translation="MRNCIIAQSGGPTAVINASAVGIYEKNLETKYFDKVYFGINGIE
                     GILNKNIIDSDSLNKDNVLNLKQTPSSGLGSCRYKLADYKINSYDYDRVINILDEYEI
                     DTLFYIGGNDSMDTVMKFSQYCKNTTCKIKFIGIPKTIDNDLLGTDNCPGFGSAAKLI
                     STLIMETYLDFSIYKNNGIFIVETMGRDTGWLAASSSLARLNDTPLVDLIYLPEIDFY
                     EDKFIEDVRKIFKEKNKAYIVASEGIRDKYGNFICEQKTSAHDKFGHSQLGGVSNYLK
                     NLIVSSSITTRVKTLELGVIQRCAMHLASDTDLKQAAEVGAYGIELSKKGYTGVMAII
                     NRTCNNPYKYEVSHTDISKIANKTKYFPKEWINEECNYITDEALNYLYPLIQGKPDIK
                     YKNGLPYFSIIY"
     gene            94899..96227
                     /locus_tag="PC512_000303"
     CDS             94899..96227
                     /locus_tag="PC512_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440083.1"
                     /translation="MMKIAVITTEFLKEFVDNSIKKLNINAEIEIYIYRDFSHVGDLY
                     LEIEDRFDGFAVSGPIPKKAITKKAGTIKKPLVDFGTDLQSYYDMFLKLIFKYNTLDF
                     SRAYFDLTDWADNPKDISYYLSNGTFGDLMDSIDENASKMSLSDIAKLEKKIAKKHIN
                     LWNEGKIDFSTTRFSSIVPMLQNAGVNFHFIYPDIDLLKNTFNNLIKDIHLHRMKGNQ
                     PSVIYITVKDTNYDDSTLDQVYKILNSIKKDKLTDFIIEKNSNSFKIFTKCETIKSLT
                     KNFTACYIKESIENSTNIKVCVGYGIGNDIKQAMSSAISANKESKINHLNYSFLVNEN
                     YETIGPLLCDKLLTVSNKVTPHINTIAKSSKLSTLTIQKIISVTEILQRDEVTPKELS
                     SCLNVTVRTANRFLSSLLKSGNATILYEKQNSTKGRPERVYKLFISENKY"
     gene            complement(96355..97545)
                     /locus_tag="PC512_000304"
     CDS             complement(96355..97545)
                     /locus_tag="PC512_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2440084.1"
                     /translation="MKNFFKEAQSIEGEIIRWRRYLHENPEIGCNLPKTVTFVTSTLE
                     KMGYSPKLTSNNGIVAVLDSKNGGKTLLLRADMDALPIMEETDLPFKSKNKDASHSCG
                     HDNHTAMLLGAAKILMDNKHLLKGRVKFVFEPDEETTRGAKSMIDDGILENPQVDAAM
                     AFHSMVGKFLNTGQVAYSRGPAMASADIFEITVEGKATHGASPEFGVDPINIMSHIQI
                     ALNTILSREKPQKEPVVLTIGMFNAGSVPNAIPNKASMSGTLRTFDQSVREKLKNRII
                     EISTGIAKSFGGNAKVEFKMGTPAVINDLDVGDEIVSYVKEVIGNENVIDFPSAMGSE
                     DFSEILLRVPGVFLWIGMGSISQGYNFGMHNPKAIFNEEGLVYGSALFAHCAVKWLEN
                     NFSR"
     gene            complement(97651..99030)
                     /locus_tag="PC512_000305"
     CDS             complement(97651..99030)
                     /locus_tag="PC512_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2440085.1"
                     /translation="MIGSISINEIDKKRFKLDDLSKKIWENPEKAFKEFKACENTANF
                     LRSEGFDVEVGVGGLATAIRASFGSGKPVIGFMGEFDALPGLNQKVSTKQEAFELGAY
                     GHGCGHNLLCTAHVGAVVGLKREMIENNLSGTIVFYACPGEEQLTGKGFMARGGAFEG
                     LDLAINFHPNKISEATIGTSTAVNSVKFHFKGKTAHAGSDPQNGRSALDAVELTNVGA
                     NYLREHVTSDVRIHYTITDGGVAPNIVPDKASVWYYTRALSREAVESTYERLVKVAKG
                     AAMMTETEVEVEFLGGCYNTLNNHVLANLVSECMNEIKQEPWTREELDFAAELDRQSP
                     QQYKAMISKYNLPEGTHLYYGGGNVTNFNSYGSTDIGDVMHIVPTAYFFTGCTNLGAP
                     GHSWQFTSCAGSSIGEKGMIYASKIMAMFGAKILNNPEIAKKAKEEFDKSMNGKTYKC
                     PIPDDIPTP"
     gene            complement(99061..100269)
                     /locus_tag="PC512_000306"
     CDS             complement(99061..100269)
                     /locus_tag="PC512_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440086.1"
                     /translation="MENFWNPLTCFTVCVMIYAFSEFLSKKTKGAISTLLFVCIIFLL
                     GFWTNILPKDITGASGILAAMSNFGIALLITNLGTLINLEDLCHEWKTVVIALVGIVG
                     IGVGCLTVGSMLFGREYALIAAPPIAGSTVAGIIVTTVAEAANRPELAAFVILVLSFQ
                     KFFGIPITTYCINKELKFKRDNGDFLKDESKSNFKLPSMRIFKEDLGKKSSTLVYLAK
                     LSFVAMIGNFVGLATLIPGFTPANYYLNPNIACLLVGLIFTRIGFLEKGILDKSQSNG
                     IIMFGCMLMLPGGLAKVTPTALFGMIIPTIGILVVGSVFIILFTAIVGKLLGYSPRMS
                     AAIGVTCMLAYPATQIISNEGIDAMEGTEEEKQRATDYLLPKMIIGGFVTVTIASVAF
                     ASIIGPIIFG"
     gene            complement(101294..102748)
                     /locus_tag="PC512_000307"
     CDS             complement(101294..102748)
                     /locus_tag="PC512_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HDF2440087.1"
                     /translation="MNIKDTFFWGGSIAAHQCEGSWDSDNKGPAIMDFVTKGSYETPR
                     VITDKIEEKLDYPSHNGIDFYNRYKEDIALFKEMGFSALRISIDWSRIFPNGDDENPN
                     ELGIKYYEGLIDTLIENNIEPIVTLYHFELPMNLVHKYGSWNNRKLIDLYLKYSETVI
                     RRFDDKVKYWVTFNEMNHIDPQTEHSDIFTYMIAGIKYSEIENKVQTLANVGYNMTLA
                     GVKVAKLAREINPNNKIGCVFGLNPIYPYNCNPSNVLNAFLDNDRDYYQIDAMCNGKF
                     PQYKLKEYEKNNITIEVTDEDKKAFKEGKLDFIGLNYYFSSVSTPKENLSGDKSLFGG
                     IQNPYLEQSKWGWAIDPIGLRFTLNYIYRKYQLPILITENGLGAYDKIEEDGTINDDY
                     RIEYLSKHLSQMKSAIEEDNVECFGYLMWGPIDLVSATTGQMSKRYGFIYVDLDDEGK
                     GSFKRYKKKSFDWYKEVIKSNGEVLDFSTDIVVG"
     gene            complement(102768..104639)
                     /locus_tag="PC512_000308"
     CDS             complement(102768..104639)
                     /locus_tag="PC512_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2440088.1"
                     /translation="MKYKDLNENIIKLIGGKENIKSVAHCVTRLRFTLNDRSIAQTEE
                     IKKLKGVIDVVSNDVAYQIIIGTHVVDVYNEFMSMIGLSSSESSIKSERKKGIRGIKG
                     IFNSIFVVVSETMTSVIEVLLAAGILASILALLNMSGILQSDSPTYQILDTLRSATFH
                     FLPVLIAIASAKRLNVNPYIAVVLAVTLLSSSIDGVEGLSLFGINLQATTYANSFIPI
                     LLGVWAMGIIIEGLKKILPKALHYFLVPVLSLIITLSVTLTVFGPIGMWIGDGLNYAC
                     MFLIDTLGNWSVVALYAALQPLLIVFGAANFTMPISLNSVTTLGYDPIFMGAATISDI
                     AVCGAMFGYFLKTRNKEQKQLFGTVSFSALMGVTEPSVFGVFMKYRRPFVAVMIGGGI
                     GGLIAGLAQVKTYGMVWGLAALPTYLVGGEVSNFTFMIISVVVSFVAATAASYLLGIP
                     SDEKEEVKGDNEKELELIINENNSRTISIGNVAKGQVIALGEVNDKAFSSGALGKGVG
                     VIPSESKSTVISPVDGTITIVFPTKHAYGIVTDEGLEILIHIGIDTVNLDGKFFESLV
                     TQNQRVKKGDALAVFESDKIIEEGFDSTIITVVTNTSDYLDVISSNDESEELLTVIV"
     gene            complement(104629..105489)
                     /locus_tag="PC512_000309"
     CDS             complement(104629..105489)
                     /locus_tag="PC512_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF2440089.1"
                     /translation="MKIIQILNNNVALVKRGKNEIIVFVKGIGFKKRVGQVINENEIE
                     RTYILDSYDMLEHFSYLLQNSDSNNIVLINEIIEYGEKALNIKASDYLSLTLLDHLEF
                     LLKRCEKNQFIKSPLVWNVKRFYPKHFEIGMHALKLIGDSKGINLPDDEAVSIALHFV
                     NMEVNKESHDSTIVELRTLADIVSIIKYHFNVELDETSTNYMRFTTHLQYFIQRIMSD
                     EASIDEDNSIDLYKQVSQLYPKSFGSVQKIRKYIKSQFNVDISISEETYLMLHINRVT
                     QRLEAKSDEI"
BASE COUNT        34716 a        18761 c        11482 g        41017 t
ORIGIN      
        1 ataattatac caatatataa aaaaatttct aaaaaacaat aaaattaagt tataaacacc
       61 aatatatttc tattatttca atacgtatac aattagatta gaatctaacg ctagtaataa
      121 aaaattactt tcccaaagta gatataagcc tcattttatc gttcaaataa tgaaaatata
      181 tttgatttca tgcaaaaaga gtgcctaatg aactaaaaag ttcattttga gacactcatt
      241 tttttatata agtttatata gtttttaatc gttcgcattc aaccactcag ttaagacttt
      301 tatatatttc tcattttctt caacgaatgg catatgtctt gaatactcaa ataattccca
      361 cttactatta ggtattctat catacatagt ctttgcaata tatggtgaac ataaatctat
      421 tgctccacta gttactagac aaggctcttt tatttcatgt aatctatctg taaattcata
      481 tccagaaaga gttcctgtag gagaaaattc attttgtccc catcctacaa tatatgcttc
      541 agaacctgat tttttaggtc ttctcaggca ctctggagaa tcttctgtca cttcacctgc
      601 acaatacatt tccataaatc tttctaatgc atcattatat tctttgctag agtaatctcc
      661 agtatttact gcatcaagta atgctttttg gtcaacctca ctcatatatg atattcttct
      721 tttttgttct ttctcccaaa gttttgcaga agaaagagta gatgaaagga tgtaagactt
      781 aatacctttt ggtttatatt caatagcata ccaaatagcc tgcatacctc cccaagattg
      841 acctaacaga tgaatttcat caagtcctag atgttttctt agttcaataa gctcctctat
      901 ccaagtatct gcattaaata gctcaggatg cccttctaca aatgaatttc cacaaccaat
      961 ttggtcatac attattactt gtctaccact ttcagctatc ttatccaata cctcaaaata
     1021 gttgtgtgta gaacctggac ctccatgaag taatactaat ggcttcttcc cttccgtatt
     1081 ttctcctact atacggtaat acgttttaaa acctttaaaa ggcatatatc cttcagtaat
     1141 tttcatgttt atctcctcca atttgtaatt ataaacaata atcaagttca ttaacaatac
     1201 tatttaaaac ctcttataca tatttgatta tgtattttaa tctttatacc tacttttata
     1261 aatagtataa cataaaagtt aaaaatctct atactaaacc aattataaaa ttatattaac
     1321 tatataattt tattttttaa taatagtata tacatatttg attattttca tttgctattt
     1381 aaaatcaatt ttaagttttc ttcttataat aaacttcctc tttgtggtct catgttagtc
     1441 tctaaattta aaattttaca aaaaattttc ataaaataaa attatattga ttgtatctaa
     1501 acaaataggg caataaaata attaagtata gttacttacc tttcaagcaa tattagtttt
     1561 atgttagaat tttattatat tgatttacag gaggtttgca tttgaataat attaattcac
     1621 ttaaagtaat aaaattatct cttggatgtt ctcttgctat atttattgct tggctattaa
     1681 aattagaata ttcaatggtt gctggagtta tagtactact tacagtaaag gacactaaaa
     1741 gagaaactct taaaggctcc attggaaaga tttatggttt tcttttatgt actatttttt
     1801 catatttatg ttttaatatt ttaggatata atttgacttc attttcaata tttatattta
     1861 taattatacc actttgtttt ttgttaaata ttcaagatgt tattgctatg tgtgtagtca
     1921 tagcatccca ttactacctt caaggagaaa cttctatcaa atggatttta aatgaagctg
     1981 gaatatttgc agtaggaact ggaataggtg tcttaataaa tatgtatatt ccaacaaata
     2041 tacataaaat ccatgaagtt caaaaaaagt tacaggaaga agtgagtatt gtacttatag
     2101 acattgcaga tattattgta aatcctaaaa aagaaaatgg atatagtaga gatttatata
     2161 cattaaattc acttattgac agcagtattt ctgaaactta cgataatatt aataatactt
     2221 tattaagtga tactagattc ttcttagaac atatggatat tataaaaagc caacgggata
     2281 tcttagaaaa tttgtatagt tatgtatctc aactaaattc tacaccacca caagctcata
     2341 ttctatctgc ttttatacat aagataggtt atactgaatt tgaagctgaa acaggcaatc
     2401 ttcttcttga agaattaaag agactaatgc ttagtatgaa aaaccagcct ctgcctgttg
     2461 acagaacaga gtttgaaaat agagctattt tattcctatg cttgactgag ttaaaacagt
     2521 ttttagttaa tcgtaaacat gctcagatac ttagagataa taatttttat aaataaaaag
     2581 gggagaaatc tagcagttga cctgactaca aaatatcaga tataatatta aatgcgcccc
     2641 tagtaagagg gcgcaatgtt tataacttat tctactgtca tgattaaatc attattcata
     2701 tcgaacatac attatttgac caagtccaat attagctttt tcatcagtga tttctatttt
     2761 aatagtcaca tcattttttt tacagtactt cgctaattct gcaccagaac gatttttacc
     2821 actaaaatct aaagaaaatg gcttatcata tttaaaagga tattcaacag gtttaccctc
     2881 tggtgctaat gcaaacatcc catatggtgt gttcataaat cctattacag caatcgtaag
     2941 atttgatggg tctaaatttg attcactacc tgtaaatgta attgtattta ctgatgaatt
     3001 aactacacta catctaacac cttcatacat tacatgtttt tcatttatat cttctccttt
     3061 ttttccaaaa tttccaacag cctttgcccc ttcttgatgt ggtaacatag tgtgctttcc
     3121 aggtggtgct ggtttctgtg tctgttctgg ttttaccgtc tgtactattg caccaacttt
     3181 tggatatgct gtcttatcaa atggtaatgg gtggctaaga ctcttgtata tgatatcctt
     3241 tcctgctgat ttattagcat caatatctac atgatacaaa cgcccatcac caaaacggat
     3301 aagattccac tggtggtcat ttgatgtgct gtgtacataa taagattcaa ttcccatagc
     3361 atcacacaaa gctttcatgc tcctagccat tcctgagcat gcaccttttt tagtaaccaa
     3421 tgtataggca gtatttgctc cctctactgc attccagtca acatatgttg tgttattttt
     3481 aatgtgattg taggcaacta aaatcttagc atctgtggtc atattctttg tgattttctt
     3541 gttcataaaa tctgctgttg cttgtgctac tgagtttagt tgggcttgtg acagctttgg
     3601 accatatacg ctattggttc cagtgacata gctttttggt gtttttgctg ttacctcttt
     3661 ggctgtcata ccataaactg tcatactcat acctgagatt aaaactattg ttgtaatcaa
     3721 taacttggta gttaacttcc taattttctt catacttaat attctccttt ataaaacatt
     3781 gttacttcct attctctacc attaataaaa ttaatttagt atttaaaaag gtggattgtc
     3841 aacatgtata tttctccatt catacattcg tgaaatattt aaattttatg gaaaatctaa
     3901 tagatatttt ctagataatt tgtatacaat acaactcgca aatcagggta tttgctgtta
     3961 gtttgagaaa atgatgatga ttaatacatt cggaatcttt gacctataat aaataccatt
     4021 gtcttcaatc attaataatg gtaagagtaa agagaattat caataataca gttaaaatca
     4081 actttgtata catttcatac attctctccc aacaacatta tacttcttat aatttgtata
     4141 ttcaatacgt tttctgggaa aatataggat atatctataa aaatataaaa aaggagttga
     4201 acttaaaatt tgattaaaaa aaatcaattt taagacaact catttgtatt ataaaaatgc
     4261 tatatattat tattaagtaa gtcaatattt tagatattta tctatttctt attgacttac
     4321 gcttatagcc taacttattt gtttagttga tatataacct agttttaagc attattaata
     4381 tttaaataat caagtatcct ttttgtttct tgtagtttct gttctgcctc atttaagttt
     4441 tcttgaatta tagaaatata tattatatct atcaacgtaa gcattgctat tcttgaagaa
     4501 atagctcctt ctctaagtct tttttctata tttggtacta ctagctttaa atcactaatc
     4561 ttactaagat gattgtcact atatttagtt atacaaatga ccttacatcc ttttaatttt
     4621 gcattttcta tagactttat tacttctttt gattctccag agtaagatat tgctatagct
     4681 atatcttctt tatctacatt tgaagatacc ataagttgtg tatgactatc taaagaggta
     4741 aatgcctgtt tatttatcct taaaagtttc atctgtaaat ctagtgcaac taaagccgaa
     4801 ccacctactc caaatatata tacattttta gcctttatta tctgttcaac tgcttctttt
     4861 attatatctt tttcattcaa caaccttgtt tggttgatag tctctatgtt tttgtttgta
     4921 attttgttta taacactatc tatattacaa tcatagtttt catctacata tgtgtattca
     4981 ttttctttgc ccatcaaatc tttagctatc tcaattttta aatccccaaa acccgaatat
     5041 cccatttttc tagaaaacct aactatactt gctgtacttg tttttgagtt tgacgccaat
     5101 tctgatacag aaagcttact tatagcctct gtattattaa gtatgtaatc agctattttt
     5161 ttatctactt ccgttaaatc ttcatatatc tgttttaatt ttaaaatgca actcatactc
     5221 tatcacctct acctatttac tataatattt cttcttagca agtaaacatg ctcctaaatc
     5281 tggagtcaac actggtctca ctataccaaa tctcgtttta ttcaaatatt ttttaagtgg
     5341 ctctaatatt aaatctcctg acttaaacac tccacctgaa taagatacct ttatctttgt
     5401 accttgttca aaatgatgct ctaatcctat tataagccta cttaattcat aagctgcatc
     5461 atcaaatatt ttactagcag tattatcacc ttcaataact gcttttaaac atatcgtagc
     5521 aaactttgct atttctattc tatctccttg tatttcatca tttacatatt ttattatgtc
     5581 ataatcattc tctatattaa gatgtctttt tattaaatca tataattttg tttttgaaca
     5641 ccttccatca gactgcattg tgaacatttt taaggtagcc attcctatat aatacgctga
     5701 accttcatct cctaatacat agccccatcc tccacatctg tgaagattcc catctttatc
     5761 taaagcctgt gctattgaac cagtacctgc aattatattt ataccttttt ccccatttaa
     5821 agaacctgct aatgctattt ctacatcatt acctagagta taatttatat gactatatgc
     5881 attttttgtt gctacttcta atgcatacaa tacttctttt atttttccat atccagcaag
     5941 tccaacaaat gcatacgtta tttcttctac atttatctta gcatctttac aaacttcttc
     6001 caacccagtt attaataatt tcgttagatt atcaaatcct atttgattat aatgacaagt
     6061 tcctttggtt atggttccta ctatatttaa ttcttcatct actaatgtaa atgttgtttt
     6121 cgttcctcca ccatctacac ctaaaaaata catactatcc tcctacaata tctttaataa
     6181 ttctttcaat acttaatatc taaaaataac cttccaatgc tgttttttta atattgaaag
     6241 gttatcagta ctattattta ttttacaatt tttctattga ttttaaagct tcacttatat
     6301 aaccttcttg tctatctagg atactctttg cactatcctt atctaaacca ctttttatca
     6361 taaatatagc caatttaacg ctattatctg cttcttctaa gaatttttct gcaacatcat
     6421 attttacatt tgtagctatc attattattc tttttgctct ttcaaccaac ttttcatttg
     6481 atgtcttaac atctaccatc aagtttgagt atacttttcc catcttaacc atagaagctg
     6541 ttgttaacat attacatacc attttttgag ctgtaccact tttcattcta gttgaaccca
     6601 ttattacttc tgcccctact ataatgttta ttggtaaatc cgctttttta ctcatttcac
     6661 tattcggatt catagttatt gatagtactg cacaccccaa ttccttagca tactccattg
     6721 cacctataac ataaggagtc cttcctgatg cagctatacc acatataaca tccttagatg
     6781 taactcctct atctattata tcttgctttc caagttcttt atcatcttca gcaccttcta
     6841 ttgctttaaa tattgcttga tttccaccag ctattatagc ttgaacaagc tcaaaatcca
     6901 ctccgtaagt tggaggacat tctgtggcat ctagtattcc tatcctacca ctggtgcctg
     6961 ctcctatata gaataatcta cctccctgct tcattctatc tactattata ttaacagctt
     7021 ttgctatact ctccttttgt tcttcaacag cataggctac agttttatct tcgttattta
     7081 ttaattctat tatgcctaat gtatcttctt tatctatttg caatgtattc ttatttctac
     7141 cttctgtaac taaattttct aaagttttta ttaacatatc atttcctcat tttcttaata
     7201 ttaaattttt aaacacattt taattccaac tttcataatt atatttttat aataaattaa
     7261 tattttcata ataaattatt ttgttgaggg tttaaaatta aacttttgcc atggtttaat
     7321 ataatctaat ataaataatt cttcttttct tatatatcct actacattcg atttaccact
     7381 gtttttcata tcagtcaagg ctatttgtaa ctcccctgca taatgaccat attcactact
     7441 ttcaattact atatctcctc tttttattat tttaggagta ttaaatagtt caaatttgta
     7501 tcctttatat ttaacacgag attgagtaga ccttatcaga ctgtcagata tgtcccctct
     7561 attaaaatgt atttcttcaa agagtatctt cttctcaact tctcgtatat tttcctctat
     7621 tgctacatca aatgtaacca tatcttttct catagaacct aataccttta gctcctcata
     7681 tgttggataa caatttgata ttattatatc atttatatta ttcatagcta ttatatgctt
     7741 tacttgaata tctataggta gatttctgtg catctcaatt gttggaagcc catcagttac
     7801 aggccatggt ccaaatgtag tttcattttg acttgttaca aaaactgctg ttcttaatcc
     7861 atacttatta aatctttctg tacattttat aaagtgttct aaatttaatc cactatatct
     7921 atgtggataa aagttatgac atcctgtcaa gttttcttta tttggttggt agtccattat
     7981 tgtatctata taattagtat tattactcat attgatttct attttaagat tttgaggatt
     8041 aaaagtcatt aatgcctctt cagaacctgt aaatcctata tcaagcctta ttccgtctgc
     8101 cttcgtcttt ttaaaaaaag tcaaatcttt gtagcttatt tctaattcac caaatactct
     8161 gggatttaca tcaagtatta cctcaaaacc tttaaactta gcgtattcat ttatacgttt
     8221 aaatttttta attatatttt ctttagtatc tttaactgat aataaacatg aaaatatacg
     8281 tgtaaatcca ttttcagcag ctttatctat ataatcatat atttccttag atgttgtttt
     8341 ttctggataa attgatattc ctaatcttcc catctgtgtc atctccttat atcctatatg
     8401 tgtttaaatt tatttcgaat tacacgaaac ttttttaaaa atttggtgaa aaaaagtttc
     8461 atatatattt ataaaaaaag aaaagtttac cttttctttt tttataaaca atcaacaaaa
     8521 tatcttcgtt acttatttca taactgttat actttgaaat ttatactaat ctaatatagt
     8581 ttttaatttc caatatagtt tctaattaat aagcttcttg ctcttcaact ttttcttcat
     8641 gaagcaatct cttatcgtac atcttgacaa atggatagta aattattatt gatatagcta
     8701 tacataataa gttaagaact gaagctctcc aatctccacc agtggctaaa tatgccccta
     8761 ctggtcctgg taatgtccaa ggagcagtaa ctactactct ggatactaaa ttagcactca
     8821 tagcaaacca tgaaactgtt gccattacta ttggtgctac aacaaatggt attattaata
     8881 ttgggtttaa tactattggt gctccaaata ttattggttc atttatattg aatattgctg
     8941 gtattacagt tgcttttcct aaagactttc cataagctga ttttgctcta aatgcaagaa
     9001 gtaaagctaa gcctattgta gctccagaac ctccaatcca tataaaccat tgaaaaaagg
     9061 gttcagcagc aatacctgga actgcttgac ccgcagcata tgaagctgta ttagcatcta
     9121 ataattgtat ccataaaggt cttgccaatg aacctattat tgatacacca tgtattccaa
     9181 atgaccaaaa aaacgttatt aaaaatatta gtataattac tgatggtaat gtgtcagtgg
     9241 ctgaaactaa tggagttact aatttagcta tgaagccatg ccaatcaaac cctaggaaat
     9301 aagtaacaat agccattaaa attattatta atgcggctgg tgtcagagct tcaaaagacc
     9361 ttgtgactga tgctggaact gcttctggca tggttatctt gaatttagat ttgtcagtaa
     9421 atctataaat ctcaacacct attatagatg ttacaatagc aacaaacatt gaacctccac
     9481 caagattagc cattggcatt tgccatcctt gaggaattga attataccaa gctaaaagtt
     9541 ctggactctt ttcaactatc tttaataact caggggtaag accctctatt gcagtaggaa
     9601 ctattgtcaa aaggaatgta gctgtagcta ataaacctcc tgtcaatcca tctaacttat
     9661 atgactttgc caaactataa cctatgccaa atgtagaata tactgatata ataaaaaatg
     9721 tcattctata tggtagtaat attgtaactg cattttcctt tagatactga gttacccccc
     9781 atgaatctgg taatggagga aatgctaata tcaagaaaaa tgacccaact attataagtg
     9841 gtaatgaagc tacgattcca tctcttacag ctcttaagtg acgttgttct gccaatctgg
     9901 ccatagaagt tgataattta gtgtctaaaa attctgtaaa tttatctagc atcttttctc
     9961 tccttaatta atatttattt ttattatcat taaaattttt ataaaatcaa ctttcttcta
    10021 atctaacaac actgcaacta ctatttactc aacagttctt gaacttgttt taataacttt
    10081 ggtcctccta atggactata agcttgtgct tgtattaatg cacatggtac actaacctca
    10141 tcagcaaaag cttttaaata gtcaaatcta tgtctgactt gtggagctac catagcaata
    10201 tcccatccat ttttaacttc attctcaaac tcttgagtac caacagccaa aacatctata
    10261 tctattccat tttttgctcc ttctttttgt aatgcattaa ctgctatagc acttgacatc
    10321 cctgatgaac aaacaaataa tactctcata ttgattcccc ctgttttttt atttcttttc
    10381 aatcattata gcatgtattt ttgattacag gaatacgttt gtatatattt tttcatattt
    10441 tacattttaa attgtaattt tatttcatgc atttatatct tgctttaatt gctttattta
    10501 tctaatcatt cttttgtcta aaattacaca ctacttaaaa tactcatatc ttttcttaaa
    10561 aaagaaaaaa gactatctta ttattaacat aaaatagtct caatactttt ttaaatatgt
    10621 attcctttat atatccagaa gtaacctatt attgcaaatg ataaagcaaa taaaatatac
    10681 agtctaaaaa atcccaaaga aaaacctctc ttagtttcaa caaagtatct tgtatatgca
    10741 actgcaaaag atgtaattaa tgaatttcct ataacaactc caaatctatt atctattcca
    10801 aatatagata ataacaaagg aaaaactaca gtacttacaa gagatgaaac tattagtatt
    10861 aatccacttt taaaacttat agttggaata ttataatctg ttctttgatt tttctccatt
    10921 tgtttcttag tatttttatt actttttgta ctttttgcat ttttataatt attatttttc
    10981 tttcttttct tttttttatt attagacatg tcatttacct ccaaaaggtt taggtgttat
    11041 attccctaaa ataactttat ttttagcccc tgttgcagat attacattag aaaaagaatt
    11101 atttaatgtt tcattgccca agattacaaa tgccaaagcc tcctttgcat cagaagaata
    11161 cccatattca tcttgagtta atacttcaac ctctaataat aactctttta tatatcctat
    11221 taaagttaga ttatgagctc ctccacctcc aattaataaa gtatctacat taacctttgg
    11281 aagtatgaag tttttataat tataatatat agcttttgcc gtaaacatag ttactgttgc
    11341 tatcaaatca tatttatcta catgtttata tttgttaagc atgttatcca aataaacttg
    11401 tccaaatacc tctcttccag tgcttttagg tggcgcttga ctaagatact tatgactcat
    11461 caaatctttt aacatttctt cattaatttt accttttgat gcaaagtatc catttttatc
    11521 atactttcta ttaaataatc tttgacatac tccatctatt atcatatttc ctggtcctgt
    11581 atcaaatgca aatacatcat ctatgttaca tgatttaggt attatagtaa tatttcctat
    11641 tccaccaata ttttgaagtg ctaaattttt attgttatca ctatataata aaaattcact
    11701 atatggtact aatggagcac cttctccacc tgctgctata tccattactc taaaattaga
    11761 tattaccttt gtatttgttt catatgctat aactgctggt tcacctattt gaagcgttga
    11821 agatacaaaa ttattataac ttcttggtat atgaaagatt gtttgaccat gagatgcgat
    11881 aaaatccaaa tttgctatat gaaagtttgc tttatgacac actgatttta cagctttact
    11941 aaataaatat ccaagcttaa aatttaagct acagattaaa tcaacactcg attcctcttc
    12001 tatacagcac tttcttattt cgtcttttat atctttagga atttctagag ttataaattc
    12061 tatttgctta actttagtat ttctaccatt cccactaatt tcagctagta ctgcatcaac
    12121 tccatctaag gaagttcctg acattaaacc tacactatac atagttatca tccttttaag
    12181 tttatagtta ttcctcccca aatcaaggta ttaagtttaa taattttaga attaatctta
    12241 tttcatcttt aattacgata atttactctt acgaaattaa tcgagttaat cttatacacg
    12301 ttttttacct tagctaaatc ttacattaat ttattttcag tgtcaatgta ataccatgta
    12361 attttttttc acaaacaaaa catattctct ctccaaaaac catattaaaa tagttactac
    12421 aaataaaaaa cataccaggt acctatctga tatgtttttc atatataata attattattt
    12481 tataatatag atggagcatc atttaaggca ctaattaaat cttcactatt ttcaagaact
    12541 aaatttattc ttattgtata tgtcgatttg tatatgatga tagattttat agtctaataa
    12601 cctaactatc tatgcttaaa taatccgata tatcataaaa gtagatatta aaaattgtat
    12661 atgaaccaat tttcgaacat acctcaatct catgccctaa actatctatc attttcttta
    12721 caaaatacat ccccattcca gtagacttat acaattgatt tcttccattt ttccccgtaa
    12781 atcccttgtc aaaaacccta gatatatctt cctcatttat acctatacca aaatctttta
    12841 tagataatac cactccattt tctaactttt ttgaattaaa ttcaatctta ccaacttcct
    12901 ttgaatactt tatagcatta ttaataattt ggtctaaaac atatgacatg catttagaat
    12961 ctgtgtaaac atcattttct aattcattca aactaacttc tacattattt tttataagca
    13021 aaaatgaatt attttttata gacattttta ccaatttttc taaattaaat ttatttataa
    13081 atacatcttc aaacatagtg ttgcttctac tactatacaa aatagagttt actaaaaaat
    13141 ttatctttgc aacctgattc ttaatatcca aactatcttc tatgctactt aacctatctg
    13201 taattatact taaagaagat attggaattt ttatttcatg aacccattta gctatgtact
    13261 catccaattc ttttaatgat tgtttataag tctctatgtc actattattt tttattttta
    13321 agttttctat aatatctttt attagatttt cttcaaaaga ttgtccatca actaaataac
    13381 tatctatttc accactattt tctatacaat tatataaatt tgtgtaacta tttctaaaat
    13441 ttatataatc tataacaaaa aataccatta ttataaacag cactaaaaaa tctaaatata
    13501 ttaactctga atatttattt ttaaaaatat ctatagcaaa taagtagata tttattatac
    13561 taactacaac taaaggtaga gcaatatact tagacctacc tttcaaatat tttactagca
    13621 ttgtattata tatcctatcc ccttcttagt ttttataaaa tcatcaaaac ccagttcttt
    13681 aactttactt ctcaatctat tcatatttac agtaagtgca ttgtctgtca caaactcgtc
    13741 attatcccat agagtcatca taagactttc ccttgataca accctattct tattttttaa
    13801 taataatgtt aaaattttta tttcgttttt agtcaactct atacttttat ccttatactt
    13861 atgttttata atccctttcc ccacatcaaa catcaaatct tcacaataca aaatactatt
    13921 agaatcacta taattataga ctcttcttat tataccattt attttggtaa ccaatatttc
    13981 tatagaaaat ggtttggtaa tgtaatcatc tgctccatta tttatgccca ttattaaatc
    14041 catatcagaa tctcttgatg ataaaaatat taatggtaca tttgaaatag ctcttatttt
    14101 ttcgcaccag taaaatccat tatataatgg taaatttaca tctaaaagta ctacatctgg
    14161 ttttttatct ataaattcat ctaatactac ctcaaaatca tcaattaatt ctactttaaa
    14221 tccccatttt tcaagtgcta acgcaatctc ttttgataaa tcaatatcgt cctctactaa
    14281 taaaattcta tacatttgta tattctccat tatcctaata tttcactatg ctatgaatta
    14341 ttaatatcat aacatatttt atatgaattt attacccaaa ttatttagtt aatcaacaag
    14401 gagactctta ttacaagaat ctcctttctc tttattaata tatcaactaa tttttataca
    14461 ctacactctt aaacttatta acagatactg ctccatatat tatgaatatt atcaaacata
    14521 tcactaaact tagtatatat ataccaaata aatcggtcat caataaatct cctgctaatc
    14581 tcaatgcaaa ataactagat atagttgcac ttaacattgg caaagtataa aaaatagcta
    14641 cttctttaag tatagctcta tttatatctt tttctgtagt acctattttt aacaaaatct
    14701 tatatttctc tttatcttca tatgcatcac tatatatttt catatatatt atacttccag
    14761 ctacaattgc aaagactaag aataaaaaca caagcactac atatgcaaac ttcatccatt
    14821 gactctcacc ttgagcttta tatccatttt gaatataccc attttttaaa cttaaattct
    14881 tttcaatatt gttgaacatt acttgactat tttcttcttg aaataccttt gcaccataaa
    14941 aatacacttg ttgaccctta tctcttagtt taaaatatgt atcatcattt accactataa
    15001 tactttgatt aagtcctgtc cctagtactg gaacttttac ttctcccctt gaaatattat
    15061 ataactgacc atcaagtttt atcttggctt cttttgtagc tattgatgct atcgtttgag
    15121 ggctttttaa ctctattaca ttatttccac taactaatct ttcaccatac tcttttaatt
    15181 ctttatcatt accattcact ttaagagtat tacaaaaatc actatatttc attatagtat
    15241 ctgttgtatc ataagcttct tttatatctg ttttctttaa aattgttagt tctggattta
    15301 ctgagtactt tatcttatta gtatctttta ttatattctc tatttgtttt ttattcactt
    15361 catctttatc cattgaaact atgctaatag tgtacacatt tctttgttct tgggcattct
    15421 tatgtatatg cttcatagca actgaagcac caagagttga tattgttgta gttataatta
    15481 tagctattat agcataagtt ttatagtttt tatttaatcg gtagtttata ttgtttattg
    15541 caattatatt atttccatta aataatattt ttttattttt gattataata tcaaatataa
    15601 caggcataac tgatttgaat aatccataag tacctactat tattatacct ataacaggta
    15661 gtacactagt tatatctcca gttcttatat tggtagaaag atagtagcca tatcctatta
    15721 ctataattga tactatagct aatatatata tacctattcc tacctttggt attttttctt
    15781 gttttttaga tatattgatt agatttatta cactacttct acatattgtt ataaaacctt
    15841 ttacagccat tattataaat atagaaataa agattaaagt agcatatagt atagcttcta
    15901 tactaagtcc attagatacc tttatattaa atccagataa ctttattatc actacttgaa
    15961 aaaatctaga tgttattatc cctataatta ttcctgttat acaagaactt attcctataa
    16021 gcatattttc tacaaaatat atttttccta tagtatataa atctaatccc ataaaagaca
    16081 atattccaat ttctttagac ctattcttaa aaaatatatt tgttgcatac catataaaga
    16141 aaaataaaaa tactgatagt atcattatta cagctactaa cactgatagt gtaaattttt
    16201 tattttcctc ttgtaacaca tttatagcat caccatatct taataattca aaattagtta
    16261 gcacaactac tgaaaaaacc atagatataa aaaatgctag ataagttctt atgttactct
    16321 taaaattatt ataagcaatt ccaagtatac tcacttacat ctcacctccc atagaggcta
    16381 gcatatccat aatttttcca taaaattctt ttctactatt tcctttgttt aatttacact
    16441 ttatatttcc atcatttatc atatatactt catttgaata acttgctgtt agagggtcat
    16501 gtgtaatcat tataatagta gcgttatttt ctctgtttat tttttctaat gattctaaaa
    16561 gttcatatgc tgatttagag tctaaagcac cagttggctc atcagcaaat atgactgttg
    16621 gatttgtaat taatgaccta gctgctgcgc ctctttgttt ttgtcctcct gataactgat
    16681 atggatattt atctaaatga ttttctaatc caaatttttt agctatagaa aataccttag
    16741 cttctatctc cttacttttc ttttttccta atgctagagg aagtgctata ttgtccatta
    16801 gtttcatatt gtctaataga ttatagtctt gaaatataaa ccctattttt tctcttctta
    16861 attttgatag ttcattattt tttacttttg atatattaat tccatctagt attatttctc
    16921 ctgaagtttg tttgtcaagt gtagacatta aatttagcaa tgttgtcttt cctgcaccag
    16981 atggacccat tattgatata aaatcacctt cattgactgt aagagatata ttttttaata
    17041 catttgtttt aaatcctttt attccataat cttttgatat attttttatt tttaatattt
    17101 ctttcataac aatagcctcc agttgctaat tttttaatat atatttattt taaaggtttt
    17161 atataaataa atccttaagt aaatattaca ttttaactgt tagcattaca cttttgtaac
    17221 atatggaaga ctattataat tatagtagaa atatcttaaa ataaaagcat gatttacttc
    17281 tttgtataaa caaagaaaag aagctcctaa gaagcctcta atctatacaa ttattcttct
    17341 ctataaaaaa ccaaaataca cattgattgt ggcaaataca gatactataa acaagtgata
    17401 ttactactat atattaaaac aattattcct gaagataatt caataagact atcaagcaat
    17461 aagctaagca tccaaaaaga cttaatacca ttaatgtata attataccca atattaatgc
    17521 ttaaaaaacc agcaacagtt ggaataatca gagatgaacc tcccataaat atacttaaag
    17581 ctattaattg gctactactt ctaagttttt taggagaaac ttcaaatatt aatctttttg
    17641 aagtaattaa aattaaagga gtagaaaaca cttgaaaaac acacagtata ataatgatat
    17701 ttgaatcatt tgttaaagca aataatagaa actgaactgt tatcataata gcacttaatt
    17761 ttaataagtt taaactgcta tattttttta ataaataaga accagccaga tatgttggta
    17821 tctctaacaa tgactgtaaa gaccacttta aagatatctg agaatttgta gcatttaaag
    17881 ctatcatttt atctattaca gtacagttat ttgctaccac cattgagtat aataagaata
    17941 aaatacatac tagtaagata tattttttat cttttaataa ttcaataata tctttattag
    18001 ttacatttat tttcttatta atcttttcaa tatcaggtaa taatagtata tttataataa
    18061 gtaatactac aattaaacca atcgctacag ataatccaaa atatgagaat ctaagaatca
    18121 agtaagatgc taccatactt ccaatagccc atccaatcga cccaaaagtc ttaataaatg
    18181 acaaataatt attaatatta tctccacaac ctattatcca tgtatcatat aaactacagc
    18241 aagtatttaa taatcctcct gataaagcaa caagtaataa gtatattata aaagttgcag
    18301 attcagtaga aaacataata actgatgcaa ttccataaac tgataaacta attaaaacaa
    18361 tttttttcat tgtttgatac ttatcagcta atactccaaa taataattga aataatatat
    18421 tggttattgc ataactcgat aatataattc ctctttcaaa cgctgagtaa cctaattttg
    18481 ataagaaagg tgtgaatttt gttgaagcaa aggcaaaaat aatatatgag aaaaaataga
    18541 atatgataaa tttaaattta atcgctttat taatcataat caatcaaaat tgataacttt
    18601 aataccacta tttccttcct gatttaagtt tgaaagatga tattttaccg tattaggatt
    18661 ctctacaata actaaaggaa tatataaagt attttcaagt aacttattat caatttctac
    18721 taacttttcc cccatattaa cttcttgacc ttgtttaact tctaatttaa agttttcttt
    18781 ttttgttgtt gcactgtcca atccaatatg aataagaatt tgaacatcat tttgcaattt
    18841 aattcctata gcatggttag tttgagcaat aaaacttatt actcctttag tcggtgattt
    18901 aagaatattg tcctttgcta tcatagcaaa tccatctccc attaccttag ttgaaaatac
    18961 tttatcagga atttctccaa gattaattat ttttccatca atgtatgaat taattgtaat
    19021 tgcttctttt tttcttttaa agaacattat agacactcct ctacataatt aactttattc
    19081 taattatcat tacaaataac gatattaagc atactgcaat tgaggaaaaa agagccttat
    19141 agctctttcc ccattgtagt tctttaatac tgcttatgat ttgtttaatt ccaacaaatt
    19201 tataaatata ggtaaacatg ataacaatag ttattgtgta aatttggaat atctgcccta
    19261 ataagactaa atagaaagca atcatgtttt cttttatctc tttattcttt tttatattgt
    19321 aaataacata tgcactgtat actgcactaa agttagagat taaatttaaa cttgcattaa
    19381 catcattgtt taaaagttgt gaaaatgaaa tatttgtaaa taatgatgtc aattctaaat
    19441 acactatata taaaacaggt aatattagaa aacaaaccat aaccactgaa agaaatatat
    19501 tttcatcttt taatactgct gtgatatttt ttattttatt tgttatcatg tttttgttct
    19561 ccttatttaa aagttggcca gaaatcctta ttagccacaa tcatttcatc taagatttct
    19621 tttgctactt ttgcacttgg aacagtttta ctcatagtaa acgactgcca taatttttga
    19681 taactttttt ctatccatgc ttctacagct aatttttcag aagcaacttg ttgttccatt
    19741 aaaccttttt ggaaagttgg aattttacct atagacatag gttcaaccat atcttttcca
    19801 acaaggcaag gaatttcaac cattgcatca tctgcaaaat tttcaatagc tccattatta
    19861 ggaacaatca gtaaaaatct ttcctgagta ttaaatgcta atgcacaagc taattcaaca
    19921 ataaattgag aatgctcact tgcatcaaac catgtatccc ttgctgtgcc attttttata
    19981 attctttcac attcttcgaa tgtatccttt tctcttctat ccataatttc atttgctctt
    20041 gtataatttg gattagcatg ttcaacagtt tcatcagcca ttaaataata ttttaaataa
    20101 gtattaggta atgtagttgg ttctatttct aataagtcct ttgctgctct catagtttct
    20161 aaccaactag attctttgtg ttgaccttga ggtgtaaatt cctcatatcc ttttttagca
    20221 caatattctt gtaatttagg cattaaatca tttccttctt tgtccttaat acttgtccac
    20281 cacccgaaat gattcaatcc ataatatcta acatcaaagt ctttacgaga atttaaacct
    20341 aaaactctag caaatatttc ctctaaacat actggcatat cacaaatatt aataattctt
    20401 gaatttggtc ttaatacacg acatgcttct gcaactatag ctgctggatt tgaataatta
    20461 agcatccaag catttggaga atatttttcc atataatcaa tcatttcgat tattggacct
    20521 attgttctta atccataggc aattccacct gccccacaag tttcttgacc aacaacccca
    20581 tattttagtg gaattttttc atcttgttca cgtaaagcat ataaaccaac acgaatttgt
    20641 gccattacaa aatcaatatc agtaaatgct tcttctggat ttgttgtata actaaattta
    20701 atttctggat ttttctctct aacaattatt gcacatgctt cagcaacttt tctttgtctc
    20761 tcatcattat tatcatataa tttaattgat tcaataggaa atttagcaac actttcaatt
    20821 aacattgtta caattccagc agtataagta ctacccccac cagcaattag tatcctctgt
    20881 ctttttcttt ccatctttcc ttctccttta taataaattt tcaaattctt ctcttacact
    20941 tggtactgaa agcccaataa taatctgaat agcttttcca ttatgcacta aaccatgtgc
    21001 acctactgcc ttaaaatctt cttctttaga aataattgag tcatctttca aggttaatct
    21061 caacctcgta gcacagtttg taacatctac aacattttct gctccaccaa ctaattttat
    21121 gtattcagat gcttgttgag aggctttact caatttattt cctttttcat ctttagtttc
    21181 taagtattca tttttagtat atagttttgt ttcttcacta tcttcttctc taccaggagt
    21241 tttcatatca aacttcttaa ttaagaaagt aaatacaaag aaccagataa atgaaaatat
    21301 aatccctaca acaacttgaa caacatatac cttccagtga tacattccaa gaggaagcca
    21361 atttaataca acccagttaa taattcctcc accaaaatca ccaacaactc ctaaggcaaa
    21421 cgaaatcgtt tgcaagcacg catctaaaaa tgcatgtact aggaataaaa gtggtgctac
    21481 aaataaaaat gtaaattcta acggctcagt aattccagtt aatactgcag taagagtagc
    21541 aggaatcatt aaacctaata cttttttctt tttttctggc tttgcagtta catagaaagc
    21601 accaaataca cctaatgaac caaacacctt cgataatccg gataatgaaa atccgattgg
    21661 atacatttcc tttagagtct tagctgaagt ttgaaaatcc tgaatatgag tagcccaata
    21721 tactgatgta ccacctggaa caacaacact atcataacaa attggtgcat atacaaaatg
    21781 atgtaatcca gttggtatta aaatcttttg taagaatgca taacaccaaa ctcctatatt
    21841 tccactattt ataaaaaacg tttgcaaatg tctaataaca ttttgaatat gaggccaaat
    21901 aaaacaagtt aataatgcaa ctggtatcat aacaaagaaa caaattgcaa ctacaagtga
    21961 tgagcctcta aataatccaa taaaatctgg tagttcttta tcataaaatc tattatgaat
    22021 ataaatgaca atacctgata ttaacaaagc accaaccata ccagtatcta atgttttaat
    22081 accagcaatg cttacaagtc cacttccagc acttatttca gctgcgaaat caactccaaa
    22141 gctttttccc caaaaactta acatagaacc tacaaaataa ttaaaagtca aatacgttgc
    22201 taaagcctcc atacaagctc ttgcttgttg cttttttgca agtgctattg gtaaagaaat
    22261 agcaaataat aatggtaatt gattaaatac catccaagct ccactagata ttacacccca
    22321 aaattggtac caaatatttt ctggtgtagc aagtgaaccc ataattgact gattttgaaa
    22381 tacaattgag aatccaacca ttatcccagc aaaagcaaat aatagtgttg gtgtaaacat
    22441 tgcccctcca aaacgctgta ttttcttcat catataaatt actcccctcc tcatattttt
    22501 agtttatctt tggccttaga tatctattat tttaacaggt taataaatat atacaatctt
    22561 tagggtacat ttggagctta ttcacagtca aataagtttt tgcacatttt tatgttcaaa
    22621 ttctcataaa aaaaaagaat gactacaatt tgcaatcaat cccttctgta atcattctat
    22681 gccttttata aatactatat ttaataaata ataactcaat caatataaaa tataacattg
    22741 tcaatttata actagggtgc atttgtaaaa atgagatatt agtcgctgaa atataaattg
    22801 attcatcact taaatcagtc aatgtattat ttttaaactc tgtaattgaa attattttag
    22861 ttcctattaa ttttaatctt ctagcaatat taagtgtatt ctcattctca ccacttaggg
    22921 atataataat cataacatca tttttactga caatattgta aaaagaatca tcaaatgttc
    22981 ttccctcaaa atcatatatt atttcttgac atgataagaa cattctcttt atctgttttg
    23041 caactacatt ttgaatatca cctgaaccat aagcgtatat tgttcttgat tcataaagaa
    23101 gtttacacaa tgcatcataa tctttatttt tttgatcttc aacatactta attattgaat
    23161 tacatgcaat atcaaatgac tgattttcta tgacatgaac cttttctgat tcccagctta
    23221 ataatacttt aaactcactg aaacctttta aatctaattt tttaacaaat cttgtaatag
    23281 ttgcacgaga cacattacat ttcatagcaa gttcatttat tgacatctta ctacaatgtt
    23341 ttttatttgc agttatatat ttccatatta ataaatctgt atcattcaat ttattataat
    23401 ttaaaaaaat catttcttct aatctcataa actattaccc cctttaatta aaaatcgtca
    23461 taaatattat accaatattc aacattaaat tacagcgtat tcttatattt actatttagc
    23521 ccataaaatt gactataaaa aatactgcta taattgatgt ttaaaaaaat gtagttttaa
    23581 ttttattctt ttatctaata attaatattt tcaagttcta gtgcttttct tatacaatta
    23641 tcatctttaa aatcagcagt ccttttacaa tcttttactt taaattctgg aatagtttta
    23701 aattcctcat cacatattcc attcttattt aaatacatac aacttgccat tctaactatt
    23761 agaccactat tttttaaatt aaacaataca gggtctatac accctccatc tccgccagta
    23821 gtttcaccaa ctaaagtcgc aaatttagtt tctttacaaa acattgcaaa tgactctgat
    23881 gatgaatata tttttctatc aacaagtaag tatatattac ccttaaattt tgaatcatct
    23941 gtagatttta tagtatagga agtatcttca aaatcattaa aatcttttat aatttcttta
    24001 ggtgcatttt cctttacact tgttggtaaa ttttctacag gatttaattt tatatttctt
    24061 gcatttgtat attgttttac tatttcatta ttatttctat aaattctata accatttatt
    24121 ttgacatcat tttttatgag tttagatacg attccctgcc aataactatc acttccacct
    24181 aaattacctc ttatatcaat aattaaagct ttatgttttt ctaaagtgtc aatataatct
    24241 ccaattattt ttaaatcatt atttatagag ccattctttg atgacattga tggtaaatac
    24301 atatatccaa tctgaccctt aataacatcc tttaaaatta attctttttt tacaaaaata
    24361 tcatctggca tttttatttt aagattcata gagtcatatc tatctacaac ttttttatca
    24421 ttaagaaaat cataccaatc attattagag tatgatttct taaaaagttc atatcttttc
    24481 ttattatcta ttacttctgt gtgtttatta tttaaatcag ataatataga tgacatttct
    24541 tctataaatt cttcatcatt ttcagtgttt tttattcgtt ttgtatattc atccttattt
    24601 gctaaccaat caatattatt aagcctctta tttacaccta gatatggata tcctgtcttt
    24661 acaacattat acacataatt aaagtcatcc accttttcct cttcagacaa ctgattcttt
    24721 tgagaataag tagaattacc taataagatt ataaatgcta aaataattac taaaaataat
    24781 actttctttt tcatgtaatt ctcatccact ttcagatttt atattttaat acattgtatc
    24841 attattttat tatcacctaa acagttaaaa gaaattcttg aagatatatt ccactattat
    24901 tctctttaaa aatttttatt tgtattttca aaattatttc atgaaagtta taaaataaca
    24961 attatattca aatatctatt ttactgctat atcctgaagg taaattctta tcagtgatat
    25021 actaaaaaag atatgctaaa aaatttatcc attataatga cttaaattta gatactttac
    25081 tgatttttat ttattagttg agaaagatat tgataattaa aaatattgat aactatagaa
    25141 atgattattt tttatagaaa ttttaaggat ataaactaat tatacttaag tctatatcct
    25201 taatttatca tgattatgag aatttttaca aatacttatc tttgtccgtt ttagaataaa
    25261 aacaagaaca tatcctgtta ttttattcaa acatccaaat ttaattacta cacaattact
    25321 tattagaaat tgtatctact tcatatatat atctgttaag tatagcttct agcatttctt
    25381 gtcttccaga cttattcttt ataactggca tttgcagtgc ataagattct aactctttaa
    25441 atccaacctt accttctact atatccttac ctataccttc actaaaactt gcatatcttt
    25501 ctttagtaaa gttttcaaat acctcatctt ctaataattt atgagctatt aataatccct
    25561 ttgcaaatgt atccattcct gcaatataag ctaggaataa gtcttctacc tcaaaagatg
    25621 ctcttcttac tttagagtca aagttaaatc ctcctggtgc tattccacct tgctttaaca
    25681 cttcatacat agcaagtgtt gcatcatata tatttgttgg aaattggtct gtatcccaac
    25741 ctaataatag gtctccttga tttgcatcta tactacctaa aacattgttt attcttgcta
    25801 tatttaattc atgttggaaa gtatgtcctg caagtgttgc atggtttgct tctatattca
    25861 ttttgaagta tttatccaga ttatactttc ttaaaaatcc taaaacagta gcagtatcaa
    25921 aatcgtattg atgtttagta ggctcttttg gcttaggctc tattaagaat tggccagtga
    25981 atcctatttc cttagcataa tctacagcca tttgtaagaa tcttgcaaag ttatccattt
    26041 caagttctgt attagtgtta agtaaagttt cataaccttc tcttccaccc cagaatacaa
    26101 aattttctcc tcctaagtac ttagttattt ccatagcttt tttaacctga gctgctgcat
    26161 atgcatatac atctgcatta catgttgtag atgcaccatg aacaaatctt ggatttccaa
    26221 acatattggc agttccccat aataacttta tacctgtctt ttccatatta acttttatat
    26281 actcaactat ttcatctaat atcttatttg tctcttctaa atctcttcct tctggtgcta
    26341 tatctctgtc atgaaaacag aaatactcaa ttcccatctt agacataaat tcaaatcctg
    26401 catcaacttt aatctttgct atctcaattg ggtctgttat attattccaa ggtctctcta
    26461 ctgtgcctac tccaaatggg tcattaccct ctccacataa agtatgccaa tagctcattg
    26521 caaatcttaa gtgttctttc atagtcttat tacctaccac ttgttcagga ttgtagtatc
    26581 taaatgctaa ttcattgtca gattttactc cttcaaattt tatctgtcct attcctttaa
    26641 atatttcact catttcatgt cctcctaata ttttacacat ataatatatg tagtatgttt
    26701 tcttaattta aaactatttt ctatctttat ttttcttttt aagctaattt aattatttat
    26761 ttttgcatta actacttcat ctaataactt aaagtcatct ttcaaagatt tgtatattct
    26821 tttatacaat ctatgatata tattgtatgt atctacattt tcacttattg gttctaattt
    26881 agttgaagtt tttattatag catcacatgc tttttgtata ttttcatata ttccagctcc
    26941 tactaatgca agaattgcaa ctccaagtgc tggtccttca cttgaattta tagtatatac
    27001 atcttgatta aacatatctg cttgcatctg tctccatact ttactttttc cacctccacc
    27061 tgaggctctt acttcattaa cgtctatatt aagattctct attatatcca tacagtcttt
    27121 aagactatat gaaacacctt ccattattga ccttgcaatt tcttttttag aatggattgg
    27181 agataatcca aagaacacac ctcttgcata agggtcaaga tgaggagttc tttctcccat
    27241 catatatggt aagtaaagca atccattaca tcctgttggt acttgactta cttgattatt
    27301 tataatctca tatacatctt cacctaaaga atttgaaact tccacttcac tttgacagaa
    27361 attatcttta aaccatttta atgacaagcc agctccttga gtaactccca taacatgcca
    27421 tgtatttggt attgcatgac agaaagtatg aactctacct tctttatcaa tttttggctc
    27481 ttttgtataa gcaaatacta cacctgatgt acctatagta gatgaaacta ctccatcttt
    27541 aactattcca tttcctatag ctcctgctgc ttggtctcca gctcctccta ccactattgt
    27601 tccttcttta agccctgtca aacttgctac atctctagtc acataacctg taatctcttg
    27661 tgattcataa actttaccta aaagattttt atctatattt aacttttcta gtacttcatc
    27721 gctccaatct ctttttctta tatcgagcaa ctgcatacca cttgcatctg atacctctgt
    27781 agcatattca cctgtcaatt tgtatcttat ataatctttt ggaagaagta ttttattagt
    27841 atttttatat atatctggtt cattgtttct aacccataat atctttgatg ctgtaaatcc
    27901 tgtaagtgct ggattagcag ttatttcaat cagtctttct tcacctacta aatcagttat
    27961 ctcctcacac tcttttactg ttcgttggtc acaccatatt atagagtttc tcaatgtttt
    28021 accttcattg tccagcataa ctagaccatg catctgtcct gataatccaa ttccttttat
    28081 acattcactg cttatatttg aactttgaac tacttctctt atagattcga ctacagcttt
    28141 ccaccaatca tttgcatcct gctctgccca acctgatttc tcttgtataa gaggatattc
    28201 atatgtacaa ctttttatag tatttcctag tttatcaaat aaaactgttt tagtacctga
    28261 tgtaccaata tccacaccta atacatactc caacttcatc cctccttgaa tgccacttca
    28321 taactatcgt tttcctatcc taattttttt atattttagg tatattttac ttgctttatt
    28381 tttgttagta tattaaacta acttatgaac taataataaa atatttaatt atctttgtca
    28441 atgcaaaata accttttatt tttgtgtaaa aagtattaca atattatttt aaggaggaat
    28501 atcaaattgg ttactgataa atacactatt cgagaaatga atgaaagatt ggtacttgaa
    28561 caaattataa aaaatggtcc tatttctagg gcaagtatag cttctactat aggattgaat
    28621 aaagcaacta tatccgctat taccaaaaaa cttattgatg aatctctagt tcatgaaatc
    28681 ggaattggaa atagtactca tagtggcgga agaaaaccca tattattagt atttaataaa
    28741 tgtgcaggga tttctttaag tatggacatt ggatacgact atatattttc ttctctatct
    28801 tacttagatg gaactattat aaattctaag aaattaacag atatacaagt aagtaaagac
    28861 aatgttatac aattgataga tgaaattata aatagttata acatatccaa aatagacact
    28921 ccttataagg taattggtct tactttggct atacatggga ttacttgtga aaataaagta
    28981 ttgtttactc catattacaa tcttaatgag attgacttat atagcatcct tagcaaaaag
    29041 tatgactttc ctattcatat agaaaatgaa gcaaacttaa cagctttagc tgagaatact
    29101 ttttcaactg tacataactc actacttagt ctcagtattc acagtggatt tggttcaggc
    29161 attataataa ataataaatt atatagtggc agaaatggta tgagtggaga aattggtcac
    29221 actatcatca tgcctaacgg taaactatgt ccttgtggaa atcgtggctg tttagaacag
    29281 tattgttcag aaaaaaaggt atttgaacag ctttcttctt tagaaaatat tcctaaaata
    29341 gattctgata tagtaaagca actatattat gaagataacc ataatgccaa aaaagttatt
    29401 catgagtttt gtagttactt aacaatagct ataaataatg ctattacaac ttatgctcct
    29461 gaaataatat atttaaatag ccaaataatt agtgatatac ctgagatatt acagattaca
    29521 aaagatatgt tagttagctc ttttaacaaa ggaataaata tagaaatttc atcattaggg
    29581 tctgaggcat ctctatatgg tggctctgct gtaaatatca agagcttttt gaatatacaa
    29641 aatttaactt taattaatga aatataaggg ttatgactat atacagccat aaccctttaa
    29701 attatacatt ctaaaattag atttattata tagtttatgc aagattagct atatttttta
    29761 aaaattgtat atcaattaag tattaacata agtacttcgt tttaaatatt aatataatct
    29821 tcctactcat catcagataa taaacttgca ttttgttcaa ccatagaaat attatcttta
    29881 cctattttct ctaattttgc tgccaattcc tttgtatcta aaaaagctga ttcaataacc
    29941 atacctaaat ttagccctga aataatttta attcgactgt cattattggc tactaataaa
    30001 gcagcattgc atggagttcc acctagtaaa tctgccatta taattatttc tgaactttcc
    30061 ttgtacactt ctaaagcttt ttttaatttt tctattgttc cttctattcc atcatcttgt
    30121 ttcatattta cagtaggata atctatagaa tcccctatta tcatttttgc agaatttaag
    30181 acttcttcag ccatattgcc atgactcatc aaaataatac tattcaattt aatacacctc
    30241 tttaaatcta taagatgtct acaagataag ttttcttatc atcaggcgtc attatagttg
    30301 taatttcaat tccttcatct aaaagtcttt taaatgcttc tttctcttct tcagtaacac
    30361 tgatattagg tcttagaact gttgtatctt ttctacttga catatttcct acatttatat
    30421 tatgtatttt aaatcctgcc tctacaaatg gaataaggtc cacaggagac ttaacaatta
    30481 ataatacatt ttgtccttca tactttcctg cagtaatatt ttttatagca gtctcttctg
    30541 taattataga tgacgctata cctgcaggtg tagccattct taaaacttgt ttttgaacag
    30601 aattgttagc tactgcatca tttactacca ttaatcttgt aacacccaat ttattactcc
    30661 acatagttgc aacttgacca tggattaaac ggtcatctat acgaatattt ttaatacctt
    30721 tcatttccat atctaatatc atcctttcct tattttaaaa tacctaatgc atataaaatt
    30781 attgaaacaa ccattactcc taaaattaag tatataggtt ttatattctt tttaagagcc
    30841 caataaacaa tcacaactag aattgcagga actaacccag gcataatttg gtctaatatt
    30901 tcttgacctt tcattgtaaa atcaccttgt tgaaagttca aagcaacatt agcttttaca
    30961 actgaaggta ttaatgcacc tacaaccatt aaacctaaaa tagatgtact ctcagttaaa
    31021 atctttaaac ttttttcaat tgaagatatt agcttagtac ctgatgtata accagcatta
    31081 aatagtggta tacttaataa tttcaatgct acactcacta caatccacag taagattcca
    31141 aatggacttc catctatcgc catattagct gctatagctc caaaaattgt ccacggaata
    31201 acgacaaata aactatctcc taaacctgct actggtccca tcaagcctgt tttaattgaa
    31261 gcaacagcct cttcagtctc ttcacttgat aactcctcca ttgctacatt aatacccaaa
    31321 atataagggg caacccaagg attagtgtta aaaaattgta aatgatttaa tacagcactt
    31381 tgtaactttt ctggattatc tttgtatact acttttaaaa aaggtagtac tgcataacag
    31441 tatgccaagg cctgcatctt ctcataattt gaagaaacag aactagtaaa aaaccagcgc
    31501 cataagacac tttttttcac cttttcattt gatttattta atgatacctt atcactcatc
    31561 ttcgtccata cctcctacta cagtatattg ttgttcttga ttttccaaat tctttttgta
    31621 aattataagt gcaattgctc caccaattaa agctacacct aataatggta ctttcatata
    31681 tactgctaaa acaaaaccaa ttactaagta actaaaatac tccttagcag gaagatatct
    31741 aagtaataat cctatcccta ctgctggaag tagtcctcca gctactgtta aaccacctgt
    31801 taaccattca ggtgtatatt tcaaaatggt attaattaaa gaaggtccaa atattacaga
    31861 tagagcaact ggaatacctg ttgtagctgc tgttaatagt actcctaaca tttgcatata
    31921 ggttatattt ttataatttc cttttttagc tccatcttct gctttatgaa ctagccatat
    31981 accaatagta tttctaagaa catctaattg taccatcaat aaagcaactg gaatacctat
    32041 agagattcct acagatgctt cttgcttagt cgtaatagtt ataaatgtgg ctactatact
    32101 tgctgtttga taatcaggta ttgatgctcc accaaagtta ctaataccta atgataatag
    32161 ctgtaatgta cctccaatat ataaccctgt atttatatct cctaagataa gaccagtaat
    32221 aaaacctgct gttactggtt gatatgttcc aaacattgtt gaattttttt catagtttat
    32281 aaaaaatcca tatagtacga ttaataataa ttgccataat tgtggctcca ttatgatttc
    32341 acctctccca aaatattttt tagttcttta aaattataac tggaatcttg ctttaggaaa
    32401 ataggaattt cttccagtgg gcattcaact tcataagttt tcccaccttc ataactaact
    32461 ccactaaata tattttccca tgtatgtcct tttggtaaat atacttttct acttctatct
    32521 ttataattca ttattggagc taccaaaatt tcatctccaa gcatatatgt attatccacc
    32581 tcccaagttt tatcatcttc aggaaattca taaaataaag ttctcataac tggtgttcca
    32641 tcttcatgcg cttctttcat cagttttttt aaataagttt ttaagctctc tctaattttt
    32701 atgaattttg taagaattac ttcaacttct tcaccataag accatatttc attaggagct
    32761 ccagttacca ttgagcctcc acctttattt gataatggtt tactatgagg caatctatct
    32821 ccatgcattc tcaaaattgg tgaaaaagta gcatattgga accatcttac cataagttct
    32881 ctaaattctg ggtctttagg atttcctcca tggaaacctc caatatcagt agtccaccat
    32941 ggtatacctg ccagtcccat atttaaccct gtatttactt gattattaaa agcttcaaaa
    33001 ctagaatcaa tgtcaccaga ccatactaaa gctccatact tttgagctcc tgcccaagct
    33061 cctcttacaa gagttacaac agactctatg tcattatgta aaccatcata aatcattttt
    33121 aaataatcaa taggataaat attaccacaa cttaaaacat ttcctttttt atatctatag
    33181 ttatcaaaat catacacaga atagccaggt tcagctacat ctaaccaata atagtcaatc
    33241 ccaagttgtt tataattttt atctattcta tcccaaacat attctcttgc attttcattt
    33301 gtcatatcta caaagactgt atttccttga atttgcattg tcattctaac accacgatta
    33361 acattgacta aatagccatt ttctaaataa tcattgtagt tttctgcatc actttgaact
    33421 gtaggccata cagatactat tggttctact gaatactctt ctttcaattt tttaactaat
    33481 tctttaggat ttttccaata atctaagtca aatttatatt caccttgctt aggccaatga
    33541 aaatagtcaa ttgcaattga tgaaagctta attcctcttt tagaatattc cttcacaaca
    33601 tctaaaactt cttctgaagt tctatatctt agtttacttt gccatagtcc taaaaggttt
    33661 tcaggcatca taggaacagt tccagtaact tgagaataat ttttatttaa ctcttttggg
    33721 ctttctccac aagtaatcca ataatctata aaatttgtag aaaacatctt ccattctgtc
    33781 atatttttag caaaagatac ttttccaatt cccggattat tccataaaag tccataacct
    33841 agactagaaa tataaaaagg aactgatatt tgagaatttc tttgggctaa ctccaaaaca
    33901 gtattcttta aatctaaaaa tttatgttga tattgtccca ttccaaaaat cttttcagaa
    33961 ggctcagatt caaatctagt agttacttca aattctccac tatagcttgg tcgatattct
    34021 cttgatttta actttagagt agagttaaag tctttggtaa tctcaattgt ccctacatct
    34081 tctccaccat catcatgttt tacagctctt aatcgaatat attctttcaa taatatttca
    34141 tttttatcat tataaaaagt aattctatct ctatggtcta agacagcttt tatctttcca
    34201 tttttaatga ttgcacttcc atcttcattt ttattaattg taatatcatc tttatttaac
    34261 ttaggttttt cgttaagagc atagttttca tcaacaaaat tttggtctac aaacgaccta
    34321 atacgtaaag agttttttcc ccatgcttct attcgcaata gttcattgtc aaatcttttt
    34381 tcaatatagt cttcagatat ttttatcacg gctacctcct aaatcaatgg tataatattc
    34441 tatctttgtg tagcttaagt taaataatgt cgtttagtat cgttatttat aaattaggtt
    34501 ttatatataa ttcatttgta cattaaacta acttaccaat aatatacttt atttgacttt
    34561 gtttgtcaat cgctttccgg attttagtaa aattttctaa tatattgctg gaaagtcgtt
    34621 cttaatatct tttatttata cttttaatat ctgtgatgat acctatatac atctagtttt
    34681 tttaaaacac atacaggaat aacatttgcc tattatgtag ataatatcgg acttgaaaat
    34741 atgtatagtg accttataaa tacagataat aatatattag atattgttca aaacaatgga
    34801 ttttataatt ataaataatt tattaaatta tttaagaaaa tatacaattg tataccaagt
    34861 caaaaacgac aacaaataaa taaaactaaa aaagatgttg tctcaaaata tagataaatt
    34921 tatttttcat tgctaaaatg attaaaatat atttgattta atatacttga tttaatataa
    34981 aaaaagagtg tctcataaac taaaaagttc acttttagac actcctttat atatattatc
    35041 tacttcttaa ttcatttatt acctctctac attttctttc aactagtgga tacatcttta
    35101 taagtactaa ttactccact taaaaatgat tcaggtactg tccatcagtc atatttttct
    35161 gccaaatata atggtgtttc ataatgagac aataaatatt tatatctcta cttatcttct
    35221 ctaagctcgt caaatccaac tataggtata tttaaattat attctttaag tagcttttct
    35281 agctcttcta taaaaatacc tttcccatcc accatttgta tatcatttat tttatccatc
    35341 aattcattgc aaccacttaa ctcaccaaac caacgtttag aactacatgt cttattataa
    35401 ccacaacttg gactgccatc tattgcaatg atacttttta tatcataatc attttttaaa
    35461 tattcatcaa actgccttac atgaggtatt aacatttgcc tacattgttc tctaaaaaac
    35521 aaattgtcaa actgttcttt tacatgtccc cacctattta ttccatacat aatcatttct
    35581 gggcatggta gttgaattat tccataccct ttatttatta aatctatcgc tatattttgt
    35641 gctcccttaa attctgacaa tccctctact ttagaattac aatttaatat acaatgacat
    35701 actactacaa tctctctatt tctcttcata ataatctcct tagttattct taattttaat
    35761 gatactacat attttgataa ttatattatt tatttgttct atatttccaa tattctatat
    35821 agaaatatac aattagtaat cttttataat ctatactatg ataaatgtat atattttttt
    35881 aggaggtatt ataattggat actaaaaaag tcacattttc ttcaatgtgc atagttatta
    35941 atattgtctt aggtatggtt atatctatga taaatatacc attattattt ttagatacaa
    36001 ttggtactgt acttggggct gtcgtattag gtcctttttg gagtgctctt attggtgggt
    36061 gtacaaactt agttttaggt gttatatcag gtcctacaaa tatacctttt gcccttgtaa
    36121 atattgttct tggtcttatt gttggatata tttctaagaa aaaaggtttt ggttataaag
    36181 aagctattat tacaggagta attttatcta ttgtttgtcc tttaattggt actcctattt
    36241 cagttttatt gtttggtggt ttaagtggaa gtggtgctga tttattggtt ggttttttag
    36301 ttcagtctgg tcagaagata tttactgctg cgttctttcc aaggattctt agtaatatag
    36361 tagacaaacc tttgtcttgt attatggtgg tatattttat aagtaaaatg cctaaaggtt
    36421 ttataaaaca atatagtaaa aatacttcta gttcatatta ataaatcatt tattatgtaa
    36481 gatttattac tctttaaaat gctatatact catttttata taacattttt attaataatt
    36541 taattagata gtatttgtat tattttaatt aaacgtaacc tcttgatata aatttgagct
    36601 ataaatctat atcaagaggt gctattttat ttttaatata attaatattc tattacgcaa
    36661 aaaatacata tatttcatta ttttatggaa aatattactt catttaactc tatatcaaac
    36721 tcattaagta aaaatctaat tatatttaat ttagcctctg tatttaaatt tgtttctaaa
    36781 tatatatttt ctgatatttt aatacctttt cttaatttat atgcatctct agacttaata
    36841 ttatctataa aatctctttt ataagtcttg tctacaatac tgttaaacct tacagaatcc
    36901 aaatcatata aagtaagagc aacttgttca taaaattctg tccaattttt agccttatat
    36961 gactctccta atatactaaa tgatactata ctttcatttg taaaattaac atcatcatcc
    37021 tctaacgtaa atatattttc actgttactt ggaggttcat atgtaacact tggatatttc
    37081 caaatttcta cagctctatc tagtaatatc ttagttctat tttttatttc ttcttcattc
    37141 catttatcta tagatgaaat atatttattt agataaagcc tactatcttt aaatccatct
    37201 tccatttctt tcttttcttc aaatgtttta ttacttagtt ttgaattata tcctgtcaaa
    37261 gttaaatttc caattgtatg taaatattta tcatgtatct ccttatagtt atctcctagt
    37321 gattccttcc atttatttgt taatgtctgt ggcattatat gctctatatt tagcatatta
    37381 ttattgatta aattttctaa atcaacaatt tctttattat tataattctc taacctctca
    37441 agtatatata acttattctt tgacttagta ttatatatat ctttagtttc aaaagcattt
    37501 gaaaattcac tgtcagtagg aaatctttga gatgatttct tatttataaa aatatatctt
    37561 aatatattag aatagttttc tttataatca ctaaattttt taatttccct tcctaagttc
    37621 ataaatactt tattcagtgc attaggaggt acatcacata ctattcttct taatataaaa
    37681 cattctacta aattaaggga ttctacaagt acttttttat ttattatacc ttcattataa
    37741 tcatcaaata attctaatat aaacggatat gatacaaata tttcaagttt gtttatcctt
    37801 ttcaaaactt tgtttacatc attatcatca gtacatgaat aagatatctc tctataatag
    37861 ttagaaaatt taagtaaatc ttttaataaa atttctatat ctataccatt atctgataca
    37921 taccttttaa aactaaaata tactttattt ttattcggta tacttctctc ctttatagtc
    37981 aaatagtctc ttataaaact acttacgttg ctacttgtat ttttttcaat tttataccaa
    38041 taattattat aaaattcctc ttgtaactta gagcttctac ccattaacac aaagtttctt
    38101 actctatcag cttcacttaa atctaagcca gttgaattta gactttcaaa gattaattga
    38161 gggtcatctt caccattttt taactctatt tctactatag ttaatttctg tatagcatca
    38221 aacaaatcat ctattgatat attatcttct tttattctat tataaaaata taaataattt
    38281 gaaactatat tagaatttct atctgtattc atttcttctt caaatagttc atagtacgct
    38341 tttctatctt ctgctattgg ttttaacttt atttttccat ctttatctct tgagtgcttg
    38401 tttataagat aacactcctt aatctgttct tctgttgtaa taattccttt tgattcccca
    38461 aactctttta ttatttgaca catggcaatc aataatattg acacagtagt cactctttgt
    38521 tgtccatcta ttattaaata ttcttttccc atactatata tagatacaac tgaccctaag
    38581 aaatgagttc taaatccaga atctattata tcctctaaat catcaaacaa tcttttacat
    38641 tgttctttct tccagttata atttctttga tatacaggta ctacaaaact tttgtttgac
    38701 ccctctaaat aactaagaaa ttcaatttct cctgctttca tattaactcc ccctataagt
    38761 taaataaatt ccattcataa ctccatgtat ctatatatta tatcaaaatt ttgactcata
    38821 aatgtatatg aaagccttat tatatacctt tttatacctg tttttatttt attaaagtaa
    38881 atacatgatt attctataaa atatacaaat acttaatttt aaaaattatt atttaatctt
    38941 cttcatgagt aattcatagt tatttatcaa ttaaaaagag atattgcata attattcaat
    39001 acctctcttt gtatatttac attatccata tctagttatc tatttcaacc caatattaga
    39061 ctacctacta ataaatttat tctctacatc attaacaata attttgcact aaataacatc
    39121 attagcctat ctctgatgca ttttctttaa ttttatttat agttttaatc aatttatttc
    39181 tctcttcaat atgattttca aataaatcaa ttatacttcc aacagttcta aatgggtctt
    39241 ccatcaacac tttgttatcc tctataaatc cattcttgac tacataatcg actataagtt
    39301 taacaaaatg tatttgctta gtattaaagc tcttattatt taaaaactct gaaaaagctt
    39361 catttgcagc ttctctatcc aatcccacta gtcttctcac taattggctt actggagtat
    39421 ctccaaactc cttcttataa tcatcacaat tacctaactg ttttaagagt atttcctcca
    39481 acgtttcaac atcttgcttt gttatctttt tattatttct taatttaaat attgctaatt
    39541 catctttatg gctatttaaa taatactcta ccttcttttt ataattctta agattgtttg
    39601 cattatatac agaatcattt ctatcttctg ctacaatcat atcttcaaaa cttgtataat
    39661 atatcttttg actagacttt tcaagatact taataagctc tcttaatgat atacgtactt
    39721 cttctacctc aaatatatct gaatcttccc aaaaatcctc tgtcattgct ttttcaatag
    39781 tatatttttg ttgctgaatc tgtggtatag tcccaagttt tgaaagtttt tctgctgtag
    39841 ccattacatg ccttatacct ttacttgcat tattattttg taagtatgca agttgtatat
    39901 tatacataac tacatcaaat cttttagcca attcatcatc actatatgaa gttatgagtg
    39961 gtgatatata ttctcttatc tcattttgtg ctactgctcc aatattgctc caaacatttt
    40021 catttttata cttatgtaca taacttaaat tcatcctaac tatataacta tcctcattta
    40081 aagcttttac agaagttata agttcttcta acaattcttt tctaagttct gcatactcac
    40141 cttctatata tttaatatct tgaagttctt taaccatact tacctttata ttaaataatt
    40201 tttcagtaag tgtttctgtt ttatttccct caaatccttt aggattaaat ttaaaaaatt
    40261 caaaattatt acaaaaatca aatattaaga atctttcctt atccatatca acacctaata
    40321 aatctggaca taatctagtt cctctaccta tcatttgcca aaacttagtc ttacttctca
    40381 ctttcttgaa aaaaacaaga tttagtattt caggtatgtc aattcctgta tcaagcatat
    40441 ctactgaaac tgctatttga ggtaatttat tcttatcaga aaaatcatct attatagaat
    40501 ctacataatt tatactatag tcaactgctt ttacaaagtt cccaccatac tttggataca
    40561 gtttattaaa tctttcaact attgccctag catgctttgt attctttgca aaaattatag
    40621 tcttaccaat cttttcttct ccttctattt tcaacccctc tgtcattagc ttatttaaaa
    40681 ctaaatctat tgtgtcagaa ttaaatagcc actcatttac tgcattattc cctatttcgt
    40741 ctccaatact ctcatcatca ttaaatgtat tttcatattc ttccttctct tcatcagaaa
    40801 gctcatcata cttaattcca tcttccataa tcttagtctt aaactcaata ctagtataat
    40861 ctactaaata tccatcctcg actgccttat tatactcata agcatatgta ggtactccat
    40921 tttccatgtc aaaaactgaa taagtatttt tatctatctc atcctttggt gtagcagtaa
    40981 gacccattaa gtaagaatca aaataatcaa agattgactt atacttttta taaatacttc
    41041 tatgcgattc atctattata attaaatcaa aatgaccagg tgtaaacaat ctctttccat
    41101 ccttagactt cgtatcatca attgcattca tcattgttgg atatgtagaa aatatcatcc
    41161 tagcatcttc tgggctgtct ttgctatcca ataaattaca taacgccaag ttaggtaata
    41221 gcttagtaaa acttttttta gcttgcttta ccaatgcttt tctatctgct agaaataata
    41281 tatttttaat ccaattatgt cttgaaagta catcaactat agatatagca attcttgttt
    41341 ttcctgtacc agtagcacat accaaaagag ttttgcgttg cttattttca agagcctcac
    41401 atacagccct aatagcttct ttttgataat atctattgga tatttcatca tttattgtta
    41461 cagaacttaa agacttctta ctctttcttc tatctatcat aagttgtaat tctgattttt
    41521 tataaaatcc ataaactttc ctatctgaat agtcatccca aatatacata tcaaaaccat
    41581 tagtcaaaaa tattaccggt ctttgactat atctcttttc caaacaatct gcatataatt
    41641 tagcttgttg ttgaccaatt ttcgggtctt tactcgttct tttcgcctca actactgcta
    41701 atggcttacc attttcacca taaagaacat aatctacata tcccacacca ctttcattag
    41761 gcataccttg tacttctatt tcttcccata tatcttttcc aaattcccaa cctgcaagct
    41821 ttaattctat atttatatat ctttttcttg tctcaaattc gcttacttcg tctatcttga
    41881 aatcatagtt tacagtatta acttttctct tttcagttag tgactttctt aattcctcat
    41941 tttcttttat tacttcttca agctttttat cttttgaact taatctctca taaagatttt
    42001 taagttcgtc tggtctcgtc cttttctctt ccccatgaag taataaatct tcattaaagt
    42061 cttctgctgt atattcatct gaataacaat agtctatcca actaacaaat tgatgcaaat
    42121 tgttaagtga aagtattgct tctcctctct ctatgttcgc actagtatgt acagataaat
    42181 tacctaattt aactatatat tttaataaag gtaacatatc atagtctata agttctataa
    42241 aactattatt atgaatcaac gtactaagat tatcttgata aggcaatact aaatcactat
    42301 cattagcata tagccatttt actgcaagct ctaaagctct tcttgttata gttgcacaag
    42361 tagatgggct aactagtata cttttttctg cttctaagca agcagtatta aaactattga
    42421 aatttttctt cttttgtaaa aaatcaaaat tacccaaggc ttttatcccc cttttgtccc
    42481 ttagttaaaa taaatctctc taaaaactat ttcttacagc tgtttcttat actaacaaat
    42541 acttcttcat tttctgtaaa caattcgtac atatcttcaa actgtggtat atcatatcca
    42601 tgagaatcat catttctcaa ttttctaagt gtttctataa ctatagaaga atttttaggt
    42661 aataaattgt gatactcaca agctaaaagg tagtcataaa agtttttaga ttttatgttt
    42721 aaatcaattg atttataata caacattgct tttgttaatt ctagaaatga taccatatag
    42781 cttttaaagc cttcttttat gtatctagcc cataactcag gcatttcttc cttatcatat
    42841 aagattttga agttttgcag gtcatacaag caagaaccaa aatccctatt tacttcttct
    42901 attgagttcc aagataattt gtttctaatt accatacatg tccctccaat ctaagatatc
    42961 tattacatca ctgttttcaa aatagaattt atttatataa tccttaaaat ctttagattt
    43021 ataaataact tcaccttcta aaatagcttt tttaagtgct attgtataat tatctgtaac
    43081 aatttttagg tctacatcaa tgtctaatat atttcttaga gcttctgtct tagttgcaag
    43141 ttctgtaatt ggtacttttt tgatgggaat ccaagctatg tctatatcac tttctgatgt
    43201 atgtttatct gttccataac taccaaatat tatgattgct agagtatttt cttttggaaa
    43261 tacatttatt attgagtttt taatctcatt tggtatattt ctcatttaat cacctcttgt
    43321 ttattaggta atattgctta attgaattta tatccataat cttttaatct atttatacat
    43381 atttctcttt cttcatcagt aaacaactct ttatactttt cttttaatac taatacttct
    43441 aatgataaat ctaatctctt acactcccat agccttgtaa atccttcagt agctccttct
    43501 ttattgatta attctttagc agctaataag gctcctttgt tatttatcag ttgtaaaaat
    43561 cttgttggct tatagttaca ttgtaaatca gcttctttat agatatttac catgttatgg
    43621 tataaatcta gctctatttg attcatagat tttattcccc cattttaata attgtatttt
    43681 agttgaataa ctatccttta aaagcttttt gcattaatga gttaaagttg tcttctagtt
    43741 cttttagact tgtttttatt cctactttca atttgtctac ttgattaaca aactcttcaa
    43801 acttattttg aagttctatt gatggtactg gtattaatat tttttgaagt tctttgcttc
    43861 taattccttg tgcagagcta ccagttttat atttatctat ttctacccta aaagcttttg
    43921 tttgcatata ttgtgctaaa aaagcattat ttaaaatttt tttatctccc tgaattgtta
    43981 taatcctttg acccatagca aactttttta aatcctttgg tatcctacat acatttccaa
    44041 atgtatgacc ttctgtaaca aaaagtacat ctccagctac tggaaaacct cttttcatcc
    44101 aagaattata ggtgttttca gatatatatt cattaatata tttaaataca ccattcccta
    44161 cagattttgc atttattatt ctaattccat tctctgaaag aattggagtt ttaccacgat
    44221 aatcaataaa atttgtacaa tctttcaata atacaaactt ttgttcctta aaatttccaa
    44281 acatttcaat aaatcttgat ttaactaatt catccaatgc ttctatttgc tcttttcttt
    44341 tatctattaa ctcttgagct ttatctaaaa cttttgatat atctttttga gcttccattt
    44401 caggtaaatc tacttttaaa ttttttaaat cattaactga aaaacttgct tgattaactg
    44461 atttttttat tatccttggt aactgtcttc taaattcatt actattaaaa aaataattta
    44521 aatactttgg ataacaaact tctttatctg gtcgtaaaca taaaagattc attccatgta
    44581 taattttttt atttatatct tcatatattg cacttttccc taaatgtttt tcactattaa
    44641 tatgtgacat tagtatatct ccatttttca ataaatagtc ttctaatttt cctaactctt
    44701 ttatgtcagc atatcccatt ttattagtat caatataaga gtttgctata gtttctattc
    44761 ttgtaattgg atatccaaat tttgtatcaa attgtttaat actagcccca tttctaataa
    44821 attcaaaaac ttcattcaat ctatattcca tactctacac ctcaagcatt ctttctaatt
    44881 cctctaatcc atctacgatt tccttctcta actccctaac tctacctata ataacactag
    44941 gagcatcata aactacttcc tcatacacta cctctttata cttattaata gataaatcat
    45001 acccattctc tcttatctct tccacatcaa caaaaaagct ttgctctgtt ctttttctat
    45061 ctacttcacc atcaagatta tcaaatctct taataatatc ctctatatca ctatccttta
    45121 tctcatttct cttatcatcc aaagaataac catcagcttt catatcatag aaccatacct
    45181 tatcagttcc acctgttcct gttttagtaa atatcattat agctgtagat actcctgcat
    45241 aaggcttaaa cactccactt ggcattgata ttatagcttc caatttatga ttatcaacta
    45301 tttcttttct tatcgattta tgtccacctg ttgaaccaaa caatactcca tctggcacta
    45361 tacatgcgca tcttccacca atttttaaaa ctcttaaaaa aagtgccaag aataataact
    45421 ctgttttctt tgtcttagtc acttttaata aatctgctga cactgcttca taatctaaac
    45481 ttcccttaaa aggaggattt gctaacacca atgtaaactt atctttatct gtattaacct
    45541 ccgataaaga atccttatac tctatattag gattgtcaac gccatgcaac atcatattca
    45601 tagcacctat tctaagcata gttctatcca tatcaaatcc atagaacata ccattattaa
    45661 aatgctcctt cagcccttgc actaagaaaa gacttgaatg attatccctt aagtattgtt
    45721 gtgatgatac taaaaaacct gccgaacctg ctgccgggtc tactataata tcttctggtg
    45781 ttggtttaat aagtcttact atcatatcta ttatgtgtct tggagtccta aattgaccat
    45841 tagtacctgc tgtagccact ttggataata aatactcata caaatctccc tttgtatctc
    45901 tatccttact taattctaaa ttactaatac catcaactat tttagataac ataagaggcg
    45961 taggaatttt aaatattgca tctcccatgt actttgcata agctgattct ttatttccat
    46021 gtaatttttt tatgaaaggg aacacttcat tttgtactat ttcatacatt ttttctgaat
    46081 ttccttcatt agaaaactta ctccacctta aatgttgatg ttcatcatca aatatctttt
    46141 caaaagaaac acccaaaaga gttgcttctg cttcattttt tgtttctact tcatccaatc
    46201 ctttaataaa taaaagatat gtaaattgtt ctataacttc taatggatta gttaatccac
    46261 cagtccaaaa agtctcccaa atcttgtcca ctttactcct taattctcct gtaatcatat
    46321 atgactttcc ctccagtgtt cataaaataa tttaaatata tattttagtc gtacgcctta
    46381 atagttagtg tcttatgtta aatccaagtt tttactacac aattattaaa ttatttttcc
    46441 tatttacata ttttagctaa aaaactaatg caatactctt attttatgat tattatatat
    46501 accatacaaa attattttat catatatcca tcatagaagt catctacctg gataactctt
    46561 accatattat aactttttaa tattaattta aacttagaaa gaaatttttt atttaattat
    46621 atcatcttcc ttatttcaaa tttctcaatt acaatcttaa tcaaaaaata aaataagatg
    46681 ctgtctcaaa atagatataa tcttcttttt tattgtcgga atgatgaaaa tatatttaat
    46741 ttcatacaaa aaagagtgcc tcatgaacta aaagttcatt ttgagacacc ccttaattta
    46801 atcttactta ttctttccct ttattattaa cacttcacta tctctattgc ttttcctaca
    46861 catccacaaa cttccatcct actcttaaca aaatctttaa ctgactctaa acctttttta
    46921 ccatattttt tagggtcaat tacctctggg tcagaattaa gcacatcctt aaccccattg
    46981 ctataagcaa tccttaattc agttgcataa ttaaccttgc aaatccctct ttttatagac
    47041 tccttaataa cctcatctgg tattccagac ccaccatgta atactaatgg aactgataca
    47101 acctctctaa tttcagataa tctatctaaa tcaagttttg gctctccctt atatagccca
    47161 tgtgccgtac ctattgctac tgctaaagat gatacccctg ttctctctac aaactctttt
    47221 gcttctaatg ggtctgtata tgctccacca tcaccaccat ctaaatcgtc ttccttacct
    47281 ccaactttac ctaattcagc ttcaacaggt atatctgaag gcatacatgc atctacaaca
    47341 gatttagata ttgaaatatt atcttcataa ctttcatgag aaccatcaat cataatagaa
    47401 gtatatccaa ctctaagtgc ctgcatagct agtccaaagc ttgaaccatg gtctaagtgc
    47461 attgctactg gaacacttgc cttctctgat gctaccttta cattcgctaa ataataatct
    47521 agtcctgcat actttattgt tgaaggtgtt gtttgcaata ttactggtga tttaagttct
    47581 tcagcagcct ctattactgc cataaccatc tccatatttt caacattaaa tgcacctact
    47641 gcataatgcc cttcttgtgc atctaataat atttgtttag ttgtcactaa tgccataatt
    47701 tctcctccta tatgtttata ctgatttaat ttcttcgtta tttaattttg atactatttc
    47761 tctacttgtt ttgctattta ataactcatt taaaaattct tcattcatta attttgaaga
    47821 tagttgagat aatgttttta agtgtaaatt atcaccatta tctgtagctg ctatcataaa
    47881 tataatatgt gccaagcttc catcttctga ttcaaagtca aacccttctt ttgatagacc
    47941 tactgctaca cgtggtacct ttactgcatc tgtttttgca tgtggtatcg ctatccccat
    48001 accaaaacct gtagatgata tttcttctct tttaaggatt tcttctttaa acttcttttt
    48061 atctaaaaga acactagatt tatcaagtat tccaatcatt tcatcaatta catctgtttt
    48121 attttttccc ttaacatcta aaattactgt ttcttcgcta tataaagaga tattattaga
    48181 tacgttttcc gattctgcac tttcattttt atgttcatct tttgttacat ttgtattttc
    48241 tatagtattt ttctcattta ctactttagg tgtaaccatc atataaagta cagcacctac
    48301 taatgaacct acaaatatac accctaccca taaaagtggc ttattgacta atcctagaac
    48361 caaaaaccct ccatgtggag ctggtacttc tattttcatt atataagtta aaattgatga
    48421 tattgatgat gcaatcataa gtactggcaa cacttttaat ggattttttg ctgcaaaagg
    48481 tattgccccc tctgttatat gagtactacc tagtatataa ttgattaatc ctgctgctct
    48541 atcttcttct gtaaatctat ttttaaataa agtagatgct attgctatta ccaatggtgg
    48601 tgttatacaa gctgcagata cacctgccat aaataaataa tttccctgtc ctagaagcat
    48661 agttccagtt acatatgctg ctttatttac tggacctccc atatcaaatg ctgacataca
    48721 tcctattact attcccaaaa ttatagggct tgaattttgt aaccccgata gaaagttcat
    48781 catagcattg ttaagtgctg aacatggccc accaagtaac aacattgcta cacccacaag
    48841 acctacgctg acaataggaa ttataaaaat cgatttaaga ccttctaatt gtcgtggtaa
    48901 ttttcttaac aaatgtacaa atagtttaac taagtaacct gctaaaaatc ctgatatgat
    48961 tccacctaaa aaccccgaac ctgtatcaaa tgatatcatt cctccaacaa gtcctgccaa
    49021 cataccagct cttcccgata tagattgagc tataaatgct gccaatacag gaaccatcaa
    49081 gttcatagaa tatccaccaa cagattttaa tgtagctgct atttgattat attgttctga
    49141 atttgggtca aatgaataaa tcccccataa aaatgatata gcagtaagta ctccacctgc
    49201 tactactaaa ggtaacatgt gagatacacc attcattaag tctttataca acttttgacc
    49261 aaacgataaa tttccttctt ctgcaatttt actgcttgat aagtttcctt ttctaatagc
    49321 tacttttcca tcaatacatc tttgtataag ttcattagct ttatgtatac cttctttgac
    49381 aggtacttct attactggct ttccattgaa tctgtccata tcaacatttt tatcacaagc
    49441 aactattatt gcatctgcca tttcgatatc ttttgctgtt aacttatttt ctacacctat
    49501 agctccattc gtttcaactt ttatgtcaca ccctaattcc ctggctgaat tttttaatgc
    49561 ttcttctgcc ataaaagtat gagctattcc agttggacaa cctgttaccc ctagaatcat
    49621 tttctttccc atttttatac cacctttctg actcttatat tttttatata atcttccaca
    49681 ttctccaaat tacctatacc attactttca gccacacttg ctcctgttgc tgctgacctt
    49741 tttaatgctt cttcaatatg ttctggattt tccaaccata tacttaaaaa agcagctaat
    49801 gcagaatcac cagcacatgc agagctgact actgtaactg gttgagcact agcataataa
    49861 attgattttc cattataaaa ataagaacct ttttctccta aagttagcaa tatattttga
    49921 gcacctttta aatgtagtaa tttaagtaca tccttaatat cttcttcatc tcttacaata
    49981 attccaaata tatctttgat ttcttcatca tttggtttta tcaaatatgg attatactgt
    50041 agtaactcct ttaattttgg tgaacttata tcgagtattg tctttatact tttattttca
    50101 caaattttaa atatatcctc atagtaatta tcatcaatac caggaggtag acttccactt
    50161 attgataagt aacttatatc ttctaatgac tgtatcttat ctagcatatc tagtttttgt
    50221 ttttcgttta catatgaccc agagtttaca aatttaaatt catcacttcc atcatttaaa
    50281 aatatattta tacgagttgt atcttctacc caagtaggca atacgtcaaa tcctctcttt
    50341 tcgctttctt caactatata ttttcctgaa aatcctccaa aaaatcctaa tatcttagat
    50401 tctataccat aatgacctag tacaaaagtt acatttaatc cctttccatt aggagaatat
    50461 acagcatttg atgtacgatt tactaatttt ctctttatcc cattagtaga tatattcata
    50521 tctattgcag gatttgtagt taatgtatat atcattgtct tcccccttgc ttgtgctgtg
    50581 tatgttttca ttataataaa aaagtctatg aaaatctttt cacaaataga aaatcgattt
    50641 tcatagactt ttcaatttaa ttttcagaat tattatatct gaccatataa tctataatta
    50701 tcctagatat aatatacaag ggcaatctgg aagatacttc atattcagaa attgatatat
    50761 gttcatgttt gtatcctaca atatataaat ccgaatactt tataagtttt gcactttcac
    50821 tacaacagca agttataacc ttagctccaa ctaaattggc attctgtgct gattctacaa
    50881 gctctattgt atttccattc aatgaaaata taattataag ttcgtctttt tttattgatt
    50941 tagattttat tttcattatg ttggggtcat ttataaaaac aacattaaaa tcaagtaatt
    51001 gcaatttaag actaaactct tttgctacat attcagtaag ccctcttgct aaaatatata
    51061 tcttactaga tttatttaca gtttttatta tattgattag tgtagttaaa gatatttgtt
    51121 ctataactct ctgtgcttct ataaaggatt tatttattat atcccccata ttttgtatat
    51181 catcattttc atcttttact gttaatctat acctaagttc attgaatcca tttaaaccac
    51241 attttctaat tgctcttgaa acggttgctg gagatgaata tgtttcatga gcaatctcta
    51301 ctatagataa ttctggtaat attgattcat tttcatttat aaatttaatt atttcaagtt
    51361 ccgtcttggt tagattttca gaattacttt tgtttagctc aattatcata tgttatctcc
    51421 ccttatataa gttttatttg tctaaattta tcgagtaata taatatatta cctcttaact
    51481 acttattttt atatacaatt aagatttagt caatgtctat atatgtaaat ttataatata
    51541 ataatttttt gcttaaagtt tattatgtta tcttatagca ttttaaaata aaaaagaatt
    51601 gtacctctac caaaatttgg atgaagtgca atagatattc cttatactga tatgtttatg
    51661 attaaaagta taaatataaa tttcgctatg aatcatataa ttaataaatc attttattta
    51721 caattataac cccccttata aaactatatt aataatatat acagtattta taaggggggt
    51781 tgtttatatt taaaaactat ttacttttct tttaattctt ctccattagt tcttattaca
    51841 ttttgatacc aataaaaact atctttttta taacgttttt tacttccatt tccattgtta
    51901 tctatatcta catatataaa tccatatctt ttttccattt cttgagatga acaacttact
    51961 atatctattg gtgaccacat acaataagct aatatttcgg ttccatcagc tatagcttca
    52021 cctatttgtt ctatatgttt tcctaaataa tctattctgt aactatcatg aacttttcca
    52081 tcttcaaatt tatcatgcat tccaaatcca ttttcagcta tcattattgg cttttggtat
    52141 ctatcataat attgagataa agtattgtat aatccttttg ggtcaattgc ccacccccaa
    52201 ggatttgctt ttaaatatgg attctttata ttgtcagttg gattcatggt gtttttactt
    52261 gctgatactg ttgtagaata atagtatgat aaagctagaa aatccatagt attttctttt
    52321 aagattttat catcaccttc ctccataact atatttatgt tattttcttt gaaaaatctc
    52381 ttaatataga ctggatactc tcccctaaaa cttacatcag tgaaaaaata ttgtagccta
    52441 tttcttttta aagcaaatac tacattttca gggtcacaat cttctggata agatgtacaa
    52501 tctgccatca tcatacctat catcatatct gaatttattt cttttccaag cttcttagtc
    52561 aaagctgtag ctatgaattg atgatgaata gcttgatatc tagtctcttc tacattatct
    52621 acttggtcta cacaaaatgc aactgaatta aatgattcat aatgtattaa atttatttga
    52681 tttataacta tccaatattt aactttattt ttatatctat ttagtattaa ttctgcatat
    52741 ctaacaaaga aatctaccac ttttctatta gaccatcctt tatattttaa tactaaattc
    52801 aaaggagtct catagtgaag tagtgttaca ataggttcca taccattatc tattacttca
    52861 tttataagat tatcataaaa ctttaatccc tcttcattag gctctaaatc atctccattt
    52921 ggaaatattc tagcccaatt tattgaaaat ctaaaacact ttaaccctag ctctttcaaa
    52981 agctttaaat cttctttgta tgtatgataa aagtctattc cactacgctt aggataatat
    53041 ccattattat ctttcatagc aaactttatt ctttctatag tcatatcaga ctcataaggt
    53101 ttagatatat ctctatcttt atcatacata tgtacatcag ctaaacacca acctttgcca
    53161 ccttcattcc atgcaccttc taattgatta gctgctacag ctcctcccca taaaaaacct
    53221 ttaggaaact tacccaattt aatcactcct tattttattt atttaaatca tttactatta
    53281 tttaccttat attctataga ctttactatt cctactaaag acatagttat atttaactcg
    53341 ctgaatatgg tcataagagt atcttgagca tgtgcaaata acagcgaatg tgctcttttc
    53401 tctccaccag cttccccttg tataatcttg gtttgagctc tatgtgcttc tgtcataaac
    53461 ccttttgctt tagctagttt taaatcagca tttctataat caaacttttc caaatcatta
    53521 agagcatgtt taatttctgt tctagcctca cctgcacgaa gtattatttg cattgccacc
    53581 tctactaatt cttcatctat tatatgttct tcaattgtca tatttataat ttcctttcaa
    53641 tttctaaatt taaacctctt ggctctctaa ttttatctct tctttctcat aagctttaaa
    53701 aaatggatac catatcataa atagcaatac tatatttatt gctaaaacaa taagacctct
    53761 aacatcttga tttaccgtaa aagtagatat accaaaagga acataccata aattaaacac
    53821 cttacttgga attgtcacaa atcccatact cattgataag taagtagtta ttgatattac
    53881 tactgttcct atccacatag gtaacattaa aaatgggttc catgccactg gagctccaaa
    53941 tattactggt tcatttatat tcattataga agggacaata catgctcttc ctattgcttt
    54001 tattcttcca actctggata aacacatcat tataactaat ggtaatgtag cacccaaccc
    54061 tcctaaagtt atccaacctg tttgaataac ttcgtaaaca tatatattag ttgctactcc
    54121 tcctgatgct actgctgctg cattagctgc aattgcacca agttgaattg aataagttat
    54181 aggagatagt acccacccac ttattcctaa agaatatata aatactacta aaaagtttaa
    54241 gagtacaaat ccaggtaatg tctgtgctat atctgatact ggtttaaata ctctaactat
    54301 tatttcaaac atgtcaaagt tgagtccata aattaatccc cagcctacaa acattatcac
    54361 tgttataggt aacatattat caaaccactt gcttacaaaa tccggaagtg ctgaatcttc
    54421 tccgaaaaat gaaaaagaac caaataagga cattattaat ccagagaata atcctgcaac
    54481 tagcgataca agcattcctt ctcctccaaa cctgttgaag ttaaatatag ctccttcatt
    54541 cgtaatctct ggacgaatca tcattaacat taatccagca cctgcaagac cagcgactac
    54601 actcatactt tcaaatttct tattcttcat tatttccata ggcaataaaa atgctataaa
    54661 taatcctaaa agtccaaatg tatattgatt tattggactt aaatcaggta aaaagcttat
    54721 gtaattcttc aagacagaaa ctatagttac taatgagcct acaaatacca ttggcaaaac
    54781 tttcattata gttgattgaa ctgattgtac ccatatattc ttagtcatat tatttacaac
    54841 aggagtaaat ttttcactta aaaaatctat aaatttattc ataaacactc tccccataaa
    54901 tattttattt gtttgatatt agttctagtg cttcttccaa agcctttgcc ccatctagtc
    54961 ttccatatgc agttttagat atacatgcta ctggaacgtt atattcatta gccttttgtt
    55021 gaatttcttc cttcatataa tctaaatgtg gtcctagtaa taaacaatct atttctgata
    55081 aatacttatc tatctctgac tcacttctcg cttttatatc tgcttctata ccttttttct
    55141 ttgcactctt tctcatacta gttgccataa aacctgtact tgctcctgaa ccacacgcca
    55201 aaagcactct tatatttttc ataatgatac ctccaatatt tttatccatc aatttatttc
    55261 ttaatgaact ttttatttta ttatgtttat attgtactta ccaaataagt tcatttcaca
    55321 taaatatatt tcctaataat aggaaatcag ttactcttaa ttaaacatat taatatagta
    55381 taatgtatct tataatacgt acattcaatt atataattat catatcatcc agattttatt
    55441 ttaaaactat gcgagggaat ctaatgaaaa catctaaaaa agaactattt ttaaatttca
    55501 taaaaacaca acatgattgg atagattcat ctacattggc taattatctt aatgtctcaa
    55561 cgcgttcaat tagaaaatat gtaaacgaaa ttaattccaa tggtgaattt atattatcct
    55621 ctaaaaaagg atataaagta aatctcaata ataattgtca aaccaaggtt gatagttcag
    55681 aaaatatatc acctgataac aggttaaatt taattttaaa agaacttata gttaatagta
    55741 atggaattaa tatatttgat ttaagtgaag acttgtttgt tagtccagct actattgaag
    55801 gagatatagt caaagctaat aaatttatag gaagttataa tttaaagata aagcaatcga
    55861 aatttttatt gaaactaatt ggaaatgagt ctgcaaagcg caaattaatg agctctataa
    55921 tatttaaaga aacgggaagt gattttttaa gcttatttga tgtacaaaaa atatatcaag
    55981 agtataattt gaccaaactg aaagaaaata taatatatat attaaaaaaa tacaatttgt
    56041 ttataaatga gtatgctata aataacatac ttcttcattt aatgataact atagacagaa
    56101 taaaaaagaa taactacata gaatctgtcg aagtagtaaa ctacatagat aataataatg
    56161 atataagcat ttcaagagat atatcaaatt ttttagagtc tgaatacaat ataactttaa
    56221 ctagtgcaga attatactac ttagtatttc agttaacaaa caaaaccaca gtcttaaatt
    56281 atcatgaaat ggatactaag tcattgccaa attatataga tgaacatttt gttaaattaa
    56341 ctaaaaaaat aattaaaaat gtatatgact tatactttat agatttatct gatgatgaat
    56401 ttgttgtaaa atttactctt catgtaaaaa atttaatcag tagggctaaa aataatcaag
    56461 ttttgagaaa tcaaatacct cagaagttaa aagattccta ccctctgata tatgatatat
    56521 ctgtttatat ttgtaatcag attcaaattt tagaaaacat agaaatagat gaagatgaaa
    56581 tatcgtatat atctcttcat gtaggttcat tttttgatag acaaaaatta ctagaagata
    56641 aaattctctg tgcattaatt actccaaatt actatgattt acaattcaaa atagtaagag
    56701 accttgagaa gagatttaat gaatccatag aaattattca gattttttca gatactcata
    56761 atcttgattt tgacaataag gtagacatgg ttattactac tttaccaatt agcgatagat
    56821 gccctatacc ttttgtttat gtaaatcctt acctaaatag aaaggattat gataatattc
    56881 aaagtaaatt tattcagatt aaagatagaa aaaatatact tactgtacaa aatcatttag
    56941 aaatgtactt tagtgaatct ttgtttatga aaaatatata tttagatagt gctaaagatt
    57001 atataagatt tatgggaaat attctgtacg aaaataaata tgtcaaaccc aattatatag
    57061 atgatgttct tataagagaa aaaatgtctt caactgcatt taataacaat gtagcaattc
    57121 ctcatagcat gaaaatggat gctttaaaaa ccggagtatg tttaattgtt aacgataaac
    57181 cagttaaatg gggtgaggaa aaagttcaaa ttatagctat gatacctata aatgaaaaag
    57241 aaaaagaaaa gttcaattac atatttgaaa gctttattga aatattatct gagtggaata
    57301 atgttaaaga acttactaag gcagataact atagtagttt tatgaataga atagcttatc
    57361 ttattcaaaa tatctaaatc aattaattta tttccaatat atgtttctta agttattaac
    57421 ataaaataga taagctgtca cactaaaaag tctaaattaa tatgtgacag ctttttacct
    57481 aatatacctt gttttaatac tacatatttt ttgactgttg tatactagtt ataagattga
    57541 atatttgtgt tgttgtagct gtcatattct cactagcagt tgctttatcc attgcttctt
    57601 ctattgtcat agctctattt actatagaaa aataagcatc tataccctct tcattacatt
    57661 taactgcatc ttctgttgtg gctccagcca aacctattac ttttacccca tatttttttg
    57721 ccagttttgc aactcctatt ggagccttgc ccatagcagt ttgattgtcc aatctacctt
    57781 caccagttat gacaaaatct gcatctttta actcttcctc taatttaatt tcttctaata
    57841 ttatttttat tccagattct aattttgaat ttaaaaatgc taaaaaagca aaacctaatc
    57901 ctcctgctgc tcctgctcct tctacattag ctacatcttt acttaagtaa tttttaacta
    57961 ctttggaaaa atttctaagc ccattatcta actcctcaat tatttctgat gttgcacctt
    58021 tttgagaccc gtatatgtat gcagctccat ttttcccaaa cagcggatta tttacatcac
    58081 aggctatttt aaacttacat tcatctaatt cctttaatct attttctatt tttatatgtc
    58141 ttatttcatt taaaactttt ccacctaatc ctactaactt gttattttca tcataaaact
    58201 caaaccctaa ggcttgaagc atacctatcc cagcatcatt agtagcactt ccacctatcc
    58261 caactataaa atttctatag cctttattta ttgcttcttt tattatttcc ccaacaccat
    58321 aagttgtagt gtataaagga tttctaagtt cagtcggaac caatgttagt cctgatgctt
    58381 gagctatttc tattattgct gtacttgtat tttttaataa tccatatgtt gcatccactt
    58441 ttttagctat tggtccagta acttctatag tatctttttt accattcatc ccttgaacta
    58501 aggcatctac tgtcccttca ccaccatcag caagtggcaa tatctttact tgcgcatctt
    58561 ctttaacctt caatatcccc ttttttattg catttcctgc ctctattgaa gataagcttc
    58621 ctttcaaaga atctatagaa attaatattt tcatatttat ctactccttt ttattactcc
    58681 ttattttaaa catataattt tataagctta atttatcttt tattttatac tctacatctc
    58741 tctttgtata caacttatac cattaatatt cttttatctt ataaaaaggg agtgtctcaa
    58801 aataaatttc ttagttcatg agacactctt tttgtataaa atcaaatata tgtttattat
    58861 ttcaacaatg ataaggagga ttatctctat tttaagataa ttccttttta gcactattta
    58921 accagtatag ttttaacttg gttcattaag cactctacat ttacagagtt attatctatt
    58981 gatatagatt ctaattcttt ttcatttagg ttaatccatt tagctgtttt aatatttttg
    59041 ttaaatacta tgttagctga ttttgtttct tctttagaat tgtaaaatct aactactaat
    59101 gcctcttgtt tttcagcctt ttttacaaca cttaacacaa ggtccttatt agtttcctta
    59161 agtaaactat atgaataatc tacttctatt tctgattgat tcaatttcat agcattatat
    59221 ggcattttat tataagtttg tatttttgtt aaatactctt tagccatatt tgcaacattt
    59281 gcttctagtg tagatttttc atgagtaact attgctaagt ctatttttat atctcctatc
    59341 atttgagaat ctggagtagg caactttatt cctgatggac gacctgggcg tcttgccatt
    59401 tcttctttac ctaggaatcc tacacttcta aataatgtta tagctattgt gtcaaatttt
    59461 tcccctacta tttcaaactc tcttgtactg tttgtaagaa cagctactcc atgctctttg
    59521 tcagacaatc caacgaatgt tagcattgga tatatagaat ctggtctttc actccattct
    59581 tcctgttgcc aaacttccat agcatcatca tacacacttc tctttatatg tccaaactga
    59641 ttatcagaca cagaaaactt tgaagctata tttgttggta tataagttct aaccctacaa
    59701 tctcttgctt ggttatttat gttgaatact acatctatta tagctttatc atttggaaca
    59761 tttataacta tatcaaagtc aataaatgaa tctgctctat tattttttct agcttgtata
    59821 tcttttggta cttttaatct ataatttatc tttatctcat tattaaatct atttttcttt
    59881 atagtggaat ttgctactat attatcgtta aatattaatt tctcatttgg aagtggtgaa
    59941 aaatcatact catctccttc atctcctcca ttttccatca ataatacatt ttcaaaagtt
    60001 ttatttaatt ttttatcaaa tatctttaat gtcccgtttt cattaacttg aatagtataa
    60061 aagtcattat ctaccatgtc acatacttca taagcttttt ctaacatatg ttcaacttct
    60121 tttatcatat acgccttata ccccattgca ggtattttat ctttaaagtt tattgtatat
    60181 accataaatg aatcatagtt tccataatga acaatttgac ggtctattaa tcctgcatct
    60241 attacttctt tatgtaccac ttcaaaatcc aacttattat tatctttatc aaatatttca
    60301 aatgctttca ttttagttat aacttgagcg cttactattt cattcctatc gtaaggcatt
    60361 aagttaaatg ctactaactt atctaaagcc atttcacaac tcattgcatc aactattctt
    60421 cttttgtaaa atgttattaa ttggtctact ttttcctcag ctaagaaaaa tctattcatt
    60481 atttcatggt gaactttatc tgaacaacaa catccaatgc tgtcatgagc atgatttttc
    60541 attatttctt tccaaattaa ctctattaat ccatgatgat attcaaatcc tagagaatat
    60601 gcaatagaag ctagtggctc caatatgttg gttatctttg attctattct agcatttgct
    60661 gattttatat ccattcttgt tgagaatata cttctatgaa ccctcatata tttcccatct
    60721 aaaaattccc cttttattgt atctatatcc tcattttttt ctagctcttt aaatatgttt
    60781 tcatatctac ttaagaaaaa ttttctctct ggataacatt cttttaattt atatataact
    60841 tcaaatatat tcttttgaat tggcatttgg tcatgtccat ttggaagtat tatatggtca
    60901 gtagttgcac ccttatcaag aaccggtaaa tatttatcca ttcttgttct tagctcatct
    60961 tcattcattg gtagatattt tcctattgca taacctaatg gaagtatttg aaccaaaaca
    61021 gaagacccat catcactctt ccaattaaac tctgttttat tagttccttt tctttcagaa
    61081 catcctctcc aaaacattga gtattttata tcaaacccat ttagtatttg tggcatttga
    61141 gcactttgac caaatgaatc tggtaaatat cctattttca tatattctcc aaattcatca
    61201 caatctttta ttccatatag taaatttcta agtatggatt ctccaccaac taccatttca
    61261 tcagtttgag tataccaagg acctattatt agccttcctt cttgaactaa tttttttatt
    61321 ctctccttac attcaggctt aactgctaaa taatcttcta atatagcagt ttgaccatcc
    61381 atcacataat atggatagtt atgattattt tctaacatat ccattatttc ttccatatta
    61441 tttacaagta atattctaga ttcctcagtt gagaagtacc attctctatc ccaatgcata
    61501 tgaggaacta tgtgtacatt ttttttcatt gcttatcctc caaaacttat ctgataatat
    61561 tttctgtcta attaaaaatc caataaaaat actactgagt ttacaaaatt ttttaatatt
    61621 tattttatca ctataattaa acctttgatt taaatatcta ataacgtatc ttttaatgta
    61681 tctttctttg atttttttgt ttcctagtta ttattaataa tactgctgat attatagctc
    61741 caagtactgc cgcaaagaac catattgatg ctataataaa tcctgacata cttccctcta
    61801 aaagcgccaa tgagaatatc cccgctccag gcacttgaag acctatattg aagaatgcta
    61861 ctatagaccc agttatggct gaaccagcta ccaatgatgg tataacacgg attgggtcct
    61921 ctatcataaa tggtattgca ccttcagtta ttccagccaa tcctaatatc caagtttgct
    61981 ttcctatttc cttttctgat tctgaaaata aatctctgcc taaaacagta gctattgtaa
    62041 ctccaaaagc tgaaaccatc ttaactgatg caaatattgc ataaggtata aaatttccac
    62101 ttgctattgc tcctattgca aatgtatagg ctgctttatt tattggtcca cctaagtcaa
    62161 atgaaaccat agctcctatt attgcaccta gtagtattgc atttactcca gtcatcccat
    62221 ttaaccaatt tataagacca ttgttaagtg ctgctacagg ctttcctact acaaataaca
    62281 tcaataaacc tactaccaaa gaaccaacta ctggatatac ccaaaaactt acgaatccag
    62341 ctaatgtgcc tttggctggt atattcttct ttaaaaattt tactatataa ccagcaagta
    62401 aacctcctaa catacctcca agaaatccac tacctattaa atcagctgct agacctgctg
    62461 caaatcctgg tccaagacct ggtttttcag ctagtgagta agacatatat gctgataata
    62521 ctggaaccat caatgtacct aacatacctc cagaaagctt tcttaattgc cataaccaag
    62581 aaccttcttg attgtatagt tcttgtagac caaatgcttg agatgctaat actgcaaatg
    62641 caagtatcat acctcctgcc acaataagtg gtattatatg agatactcct gtaagtattg
    62701 ctgattttac atcttttttc catgatgatt tttcacaata tgatatatca gatgattttt
    62761 ctatataatc acctttacct tgtttttgtg ctacttctaa agcttcgtat attatttctt
    62821 ttgctctttt tagtggagct gctactgacg tttttatgtt tggcaaatgt tcaaatcttt
    62881 ctgtattttt aggtgctaca tctgttgcat atattattgc atctgccctt tttattatat
    62941 ctggtgtatg agggtccacc ataccattag ctccttgctt ttctacatac acatccacac
    63001 cgatttcttt accagcttta attaatgctt ctgctgacat atatgtatgt gctatacctg
    63061 cagggcatgc tgttattgct aatataattt tttttgattc attttgaatc ctaatctctt
    63121 cttttatttg ttctttcttt tcttttatat ctaagttatt aaataactct ttcttagttt
    63181 ttgaatttaa caacatattc atataatctt catttgacag tctagtaact aactcagaaa
    63241 gtatttgtat gtgtgtattt ccaccttcat tttctggtac tgctattaaa aatattatct
    63301 ctactttatt atttgggtct acgctttccc aattttctat tggtgtctct aaggtcatag
    63361 ctgcaaatgc agcttcttta actgacttag attttccatg aggaattgca agccctcttt
    63421 caaaacctgt tggagataaa gtttctctgt acattacagc ttctaaatat tcctcataag
    63481 atgttaactt gccttcatca tatagctttc ttgctaagaa ctttattgcg tctttctttg
    63541 tttttatttt ttgttttaaa aaaacaaggt tttcatttgt gattttctta aattccaaaa
    63601 ttacgccctc cttaaatcat ttaatgctat gaatatagca taaaataaat tatgaaaatg
    63661 tttttttgaa attatacaca caatttcttc ttaaaaaata aagatttgtg tatttataca
    63721 caaatctcta tcttaaccag tattgctcta ttattgctct cataatcatc ataattggaa
    63781 ccttatctga tatattgtac ccatttactt gtttaattgt tgaatagcaa tataaactta
    63841 tatctgcaat ttgttgcaat tgattttcac atatatgtgt tagagctact accttacaac
    63901 ccttattaac tgctgtcttt gctacttcta taacttcttt cgtttctcca cttaaactaa
    63961 gtgcaaaaaa catatcttgt tcacctaatt ttcctatatc atgaagtact tcatgtcttt
    64021 gactatagta agttatatta tcatgcccac ctctaatttc ttttactaat atctcacata
    64081 aaggaatgtt ttgacctatt ccataaacta taatactcct agatttttga attatatctg
    64141 ctactttatt tattttttca taatctatta gctctaatgt cttttttata tctgattcaa
    64201 aaccattttt tggctcttta tcctcatttt ttaactcttc ttttaaatta ttttttagtt
    64261 gagagaaacc atcatactcc atttttttac atagcctaac tatggtattt gggacagtaa
    64321 aaaatttatc tgctaaagat tgtattgata attttactat ttcttctttg ttttttctca
    64381 tatattcaat tatcatgtct tctgtatctg taaatttata ctcatatttt tttgctcttt
    64441 cataaaattc catagtttct cctccatcta ttttattatt cataagtaaa attcaaaaat
    64501 attagctaaa attttcgtta atataattat aatttaatat ttttaattta ttaatgcata
    64561 ctactctttt tattatacat aaaaaatgtg tacttcctat attgatagag atgattcaag
    64621 tttttatttt gatacatctc tatcaatatt tttttagaaa atacacattt ttttcaaata
    64681 cttattttta attaaaactt taggtaatct attctttata tataattatt agacttgaaa
    64741 atatctttaa aatcaaccaa ttcaatatta tttcttttta accacatttt aacttcctta
    64801 tcacatagca ttgcatgttc atatactctc tcttgaataa gagaagatga ttttataaga
    64861 ctataatcta taaatcctgg atgagtaacc atcaatgtta tatctttatc taaatttata
    64921 tatttttctt caaataattt aacaaaagat ttatttaact tgtaaaaatc attctgagga
    64981 tatttacttg gcatgctaat acatgaatcc aaataatagg gacaacttgg tataccgtat
    65041 tcttttgcag catcacacat tgctgatatt gatacatctt cttctatacc atgtatatca
    65101 atatactcag gcaatttact catatacaac ttgtaagttt caatttgagc acaaacttct
    65161 tcatatactt cttcataatt aaaaacctct ttacctgtca gtagttgcgt tcttcttatt
    65221 ttgctagaaa caaattttcc accttcatct aacaaattct ttatcttaat atgttctttg
    65281 caacaaggtt ctcctattac taaattaaca tgtaaaccaa aacatacatc atcatttttt
    65341 accatttcta tagcttgtct tgaaaaaggc atattcacca tgattccagc acttgtaaca
    65401 ataccgttct tataagaaga tattatccct agtgtaacac cttctgaata tcctatatca
    65461 tctgccctaa ctactagttt cttcatttta tgcgtctgcc tgctttctca actcatcaag
    65521 ttgcatttcc atctcatcct ttactttaac aacatccgtt cctatgatga tttgaactga
    65581 tgtattactc aatttaatta cccctttggc tcctgttttt ttaatattat catcattcaa
    65641 aatagtagca tccttcactt ctaaacgtaa tctcgtcata caattattaa gagtcactat
    65701 attttcataa ccaccacaat ttttaattat ctgtttagcc atatatgaaa aattaccatg
    65761 agaaagtttt aaattctttt ctttttcact aactttatca cctatctcta tctcaacttc
    65821 acgtcctggt gtttgcacat tatcttttat tattatatat ttaaatgtta cataatataa
    65881 tacaaagaat acaactccta caggtataac taaccacgct ttatctccat aactaaaact
    65941 taagacatag tcaattatac ttgctccatt aaatgaaccc aagcgaacac ccagtaaata
    66001 tagtacaact ccacctagac cagaataaaa agaatgaatt atatataact ttggagatgc
    66061 aaataaaaac gaaaattcta ttggttcagt tactgttgcc ataaaagaag tcaatgctcc
    66121 agcggtcatt gcacctttta cttcttgctt ctttttatct tgtgctgttt tatatatagc
    66181 ataagaaata gcaggtattg aaaacatcat aattatgtaa aatcctgtcc agaagaatcc
    66241 tgcatttggg tctcctgcca taaatctagg aatttctcct cttataactt ctcctgttga
    66301 tgttgtatat tcacccattt caaataatat gtaagcattt aaaacttgat gtaacccagt
    66361 tggtattagt gcacggttac agaataaaaa caagaatatt cctattgcac cagctcctcc
    66421 caaccaaaaa ccaaattgat tcattgcagc ttgtggatat atccataata aactaaatat
    66481 atatgataaa attaaagcaa ccactggtga tagtgtaatt acacattttt ctcctgcaaa
    66541 gaagcttaaa aatgctggaa ctttaacttt atatgtttta ttgtaagtcc atgctataca
    66601 agctccaaca attatcccac caaatacacc tgcatttaat gtatcattca ataactctaa
    66661 atttgactta aatatcatat atgcaactac ggctgcaacc attacacttg tcttgtcttt
    66721 agactttgag taggcactag ctgctcctaa taaaaataag tagtccacat ttgaaaatac
    66781 tatattagat atattagata tagctggcac attgagcata tttggaccaa ataataatcc
    66841 taatatacct gctgctggca ttacagctat tggcactagc atagtctttc ctaaaagtga
    66901 cagttgttgc atcattttgt ttaagaacct cttcatatcc aatccccttt ctatttcggt
    66961 ttaatttttt gtgaaaacga tttattcaca ttttatattt taaatattat atttgtttaa
    67021 acaaattgtc aatatttttt attcatttta tttttatcat ttagtttaac atataaatcc
    67081 ttttaagtgt attgctatat ctagtctatt tttttaattc atttttttta ttttaaaaat
    67141 atgtttaacc atgtatttga aacaacccac aaaataattc tattttgtcc tttttatggt
    67201 tgatatgatt ctattttcac tatacatgtc taaacacatt tgatataatt tgttcatatc
    67261 agttcaataa tattactaaa gacctttaag gagggatagg ggtatatggc taaaaataaa
    67321 ttttcagaga tatatgaagt attgaaagag gaaatacttg atggtaaata tacaagtaat
    67381 atgatgctgc ctactgaact tcaacttatt gaaaggtttt catgtagcag aaacactgta
    67441 cgtagagcaa tttctcaatt aaacacagaa ggatatgttc aaagtataaa aggcaagggt
    67501 gttgtagtgt tagaaaatag ttgttctaat gatttttttc taaatatgca caatttcaaa
    67561 ggtgtagaat cgattgtaga agataaaaag gttaatactg ctactagtgt tctccacttc
    67621 agcaaaatct taattgataa taagttatct aaaaagacag gttttaaagt tggtagtgaa
    67681 gtatattacc ttcacagact aagatatatt gataacatac ctaaaattct cgacattaac
    67741 tattttctat gtagtatagt taaagacctt gatgtttcta tagcacaagg ctctatttat
    67801 aaatatatag aagagtgtct aggtacaaaa attgtttcat ccagaaagat atttaaaatt
    67861 gaaaaagcta cagagcttga gttaaaaacg ctacctctaa atgattataa ttgtgttggt
    67921 gttattaaaa atagtgtata tactgatgat ggaaagcttt ttgaatatac tgaatcaaag
    67981 catacacctg aaacatttgt attcatggat gttactcaaa gatattaaaa aaattatgtt
    68041 taattaaaca taattttttt acgtttagac actttatccc atactaacct cactattcta
    68101 tatacaatta tgtgtttata caaataatta tttattgtat attttagctt taatattagt
    68161 ttaatgcttg acaatttgtt taaacatatt ataattaact tataaattac aggaggtatc
    68221 aattatgaaa aattggtgga aaaaagcaac tgtctatcaa atatatccaa aaagtttcaa
    68281 agatagcaac aatgatggta taggtgatat aaatggtatt atagaaaaat tagattatct
    68341 gtattattta ggtgttgatt tattatggtt gactcctatg tacgtttctc ctcaaagaga
    68401 taatggatat gatatagaag attattataa tatagaccca aaatatggga caatgagtga
    68461 ctttgaaaaa ctcttaaaag aagctcataa aagagacata aaaataatga tggatatggt
    68521 cctaaaccat acatctactg aacataaatg gtttaaagaa tctaaaaaaa gcaaagacaa
    68581 tccatatcgt gattattatt tctggaaaga tgctaaacct gatggttctg ttcctaataa
    68641 ctggatatcc agatttagtg gaactgcttg gaaatatgat gaaaccacta accaatatta
    68701 tttacattta tttgaagaaa ctcaagctga tttaaattgg gaaaatgaaa aggttcgtga
    68761 agaatgttac aaaatactag aattttgggc tgataaaggt attgatggtt ttcgtttaga
    68821 tgtagtcaac ctactctcca aaacacctgg attacctgat gaccctataa caggaccaaa
    68881 aggagatgga agaactcact acgctgatgg tcctcgtata cacgaatatt tacataatat
    68941 gaatcaaaaa gttttcaaac ctaaaaatat agttactgta ggtgaaatgt catctactac
    69001 acctgaagag tgtatcaact atactagaga aaatcgagaa gaactatcta tggtttttag
    69061 cttccatcat atgaaaacag attataaagg aggcgcaaaa tggactaatg aaatgttctc
    69121 tctggataaa ttaaaaaaag cacaatctga ctttcaatat aaaatgtatg aaggaaaagg
    69181 atggaatgct ctattttact ctaatcacga ccaacctaga gctttatcta gatttggaga
    69241 tgatagattt tttcgtcaag aaagtgctaa gatgttagcc ataacactat ttggtctaca
    69301 aggtactaca tacatatatc aaggtgaaga aataggtatg acaaatgcct actttactaa
    69361 aatagatgaa tatgatgatg ctgaaagtaa gaatgcatac tatcatatga ttaaatctgg
    69421 tattgatgaa aaggaggcat tgcttatact tcaacaaaaa tccagagata atgcccgtac
    69481 tcctatgcaa tgggataata ctatttataa ggggttttct aatcataaac cgtggttaaa
    69541 agttaataat gacaatatta gtgtagaaaa tgagcttaat gattctcgtt cagtatttta
    69601 tacttatcaa agattaatca aatatcgtaa acaatatgat atttttacag aaggtactta
    69661 tagattgtta gatgaaaatc ataaaaatct atttgtttat gaaagagagt ataaaaacca
    69721 aaatcttctt gttataagta atttcactca tgataatgta gtatataaat tacctgaaac
    69781 ttatttgaat aaattaaact acacaatact tgaaaccaat tacactagag atataattga
    69841 aaataaaatg gaaataaaac cttacgaaag tataatgata tattataaat aaagttattt
    69901 atgtaaaaat aggtataaca ccctggtgtt ataccaattt tactaaattc aaagtaatgt
    69961 ttatagaata tctatagatt acaataatta tttgacttct acatcattat atttctttga
    70021 atatacttta gtcatataga aatatatagg aactacaatt atcatcccac ctaatcccca
    70081 aactatcttc ataggttcat caatacctgc ttttatcagt aataatatac ttataataac
    70141 tgcaaatatt ggtataattg ctcctccagg tattctaaaa tttacatctt taccagcata
    70201 cttctttctc aatattagta cagctaaaca tgtaggaata tattgaataa atctagatac
    70261 aacacttatt tgagataatg ttgtgaatga acccgaccat gctattagta aagttcctat
    70321 gacagatact ataattgcta tataaggagc tccattttta ttagtttgtc ttatagactt
    70381 aggcattaat ccttgttcaa ccaaagcagc agcagacctt ggtgtaaata tggatgatgc
    70441 aatatttata cctccaacag atactatagt tcctattgta attatatacc cacctatagg
    70501 acctaacatc ttaatggcag catctgcaac aggagtagct gaccctgcta agccattacc
    70561 caacacccct atacttattc ccagtataag catatatatt actgatacta caaacattac
    70621 cattaccaat gctttaggta catttttctt agggttctcc atatcttttg ctgcaacagc
    70681 taaagattca aatcctgtaa aagcataaaa taaagttata gatactgcta caaaagctga
    70741 tgacgcactt tgaccttttt gtattattac aaatggggta aaattagaac cctttataaa
    70801 gaataatcct acagctataa ataaaactat tggtaataat tttcctatag tcatgatatt
    70861 atttaagtgc ttagattgtt tcattcccat aaaatttata atcccaagcc ctacaactaa
    70921 tataccaatt attatatttt taataagtgg ttctgctgct tgtggccata cagatgatag
    70981 tgttacagca aagaaatttg ccatagtagc ccaagcaatc atactaacta tccacttcat
    71041 aaatccaact tcaaatccaa caaaatctcc aaatgcctct tttgcataaa gatagggccc
    71101 tccatcagta tcaaaccaac tacctgcttc agcaaaacat aaagcaatag aaacagctaa
    71161 aagcatacaa aaaactaata ctaatatact tgctggacct atatctgtat aagcatcacc
    71221 aggtaacccg aatatacctg accctattat tgcattgatt cctaatagta caatactcca
    71281 aaaacctaac ttaatgcctt tttccattgt tattcccccc aaagccaact taatatattt
    71341 gtatttttta tttagatgct tctttaacta ttgccataaa tatttttttc atattatcat
    71401 aatctctagt catcatttct ggatgccatt gtatccctat tacaaactca cttccttcct
    71461 tttctatagc ttcaattaaa ccgtctttag atgtagctga aacaatatat cccggtgcta
    71521 ctttgttgac aactaagtga tgaaaactat taactaaaac ttctttttct cctagtattt
    71581 catataattt tgtcccctcc tttatctgta ctgtatgtgt aggtacatta gatagatgtt
    71641 gctgattgtg tttaatataa gcaccttcaa ttaaagataa atcttgatac aaactacctc
    71701 cttcagttac atttataatt tgttctcctc tacatatacc taaaactggt tttttcatat
    71761 ctaaagcatg ttttaataat ttcatatcaa aactatctct ctttggtgat attgccccca
    71821 acttattatg aggttcttct ttccatatga gtggatttac atcttgtccc ccagatagta
    71881 taagcgcatc tatattagat acctgctcct ttataatctc atcatcatat acaatcggta
    71941 caatatatgg tatagcttta cacataacta ctgattgtat ataatcatta tttacataag
    72001 ccctttcata gccaggaaac attcctcctt catcaattag taaattacct gatattccta
    72061 ttattggata tttcttttta gccaatttct tcacccctta acttatttgt gaacaataaa
    72121 aaatgctact tctcttaaag agcaagtagc ataccaagat tttatttatt tgaacattat
    72181 aatttatttt agaaatactt tttttgaata cgagtaatat aaataacttt atttacttat
    72241 attttatttt aatcctgttt agtttgactt ttttaaattg ttttaagtac aactaatagg
    72301 taaaataggc atttagattt tcctttttat caacctatta aatactgttt aatatatttt
    72361 ttccccttct atttaattca cttccctttc taccagattc acatattatc aaatccagct
    72421 cttttaacat attaagtatt cctcttacct caccttctgt tatattgtag cctaattcat
    72481 ttattgaatt aacaatacca tttctaccta tatttttatt aagattattg gcatttttta
    72541 aacactccat tactaacttt actttctcta tagatgttct atcctttaat atgcttattt
    72601 ctttactaaa atcttcagtt atatttaata agttatgagg taaatcattt attaaaataa
    72661 catcctcaga actcataatg ttaatataca tagcagtatt ttttaattct cttatattac
    72721 ctggccattc atatgcatta ataatgtctt gaacatcttg actaattgct ctcttccttt
    72781 tcataaaatg ctttaacata acttctatat cttcttttcg ctctcttaaa ggtggtatat
    72841 ttatgggcaa tacatttatc ctatagtata aatctgctct aaatctatct ccttttatca
    72901 tttctaataa atttttattt gtagccgcaa ttactctaac atctatatct attacatttt
    72961 ctcctccaac cctcattact tgattctctt gtaatactct aagtaatttg ctttgtaagt
    73021 atataggcat gtctcctatt tcatccaaaa atatagttcc attgttagcc tgttcaaata
    73081 atcctttttt acctcctttt aaagctcctg taaaagcacc ttcttcatat ccaaaaagtt
    73141 cactttcaag taaattttct ggcatagctg cacagtttat tgctataaat ggctgactat
    73201 gtcttggtga tgcattatga atagactgag ccatgagttc ttttcctgtt ccactttctc
    73261 ccgttataag aattgtataa tcagattcag ctattttcat acctaatttc ttagttcttt
    73321 ccatcttcgt tgaaactgtt tttatatcat caaaagtata tctagcaact tgtccctttt
    73381 ctctaagctt ctttgatagg ttttgctcca attttcttat gtaagttatt tcttgaatac
    73441 aaaaataata tccagtaacc cttccaaaac tctctatatt atacttattt acgtttaagt
    73501 acttattatt aaattttata acttcatcat gtgccttact caaactaaaa atctttttaa
    73561 tattctcatt ctctaattca tctatatttt tccctataat attactttga atatctagta
    73621 tatcccttaa actattatta caaataatta tgtttccctt atctgatacc attgccatac
    73681 ctaagtttga taaatttatt atggaattta gttcatctgc ttttatagta agttctttgt
    73741 atttagtatt tattcctgaa tataaactaa ttatttcatc tgtatactta attagcctct
    73801 cagtaatttc tttatcatcc agtttgagtt ttgctattat ttgaataaac gttgaactat
    73861 caatatacct atggcctaaa tcaataactt cttctatata ttttggaact aaacttgact
    73921 ctcctggcgt tatagctatc ttaatatttc tatattcttc attgggattg tatggtataa
    73981 aattcaaatg atttattcct atattgtata aattagatat tgtttccaat acagtatgct
    74041 tattatcgtt tactactaat acatctattc cttctggcaa tgaaaataac ttatatatat
    74101 ccttttgctt tatgctccta tttatagtta ttatctttga gacatcttcc acatattttt
    74161 ttatttttaa tactctatca tctatcatta ccaatattat gtcatctttt attaattcct
    74221 tctctgttat tttatttaaa taataatttt ttatcattac tttatcttta aagatcattt
    74281 ctagattttt atttaagaaa cattctaatt tagacaaccc atcagttact actgctattg
    74341 ttttcatttg attactcctt ttaaaatata ctctactctt ttataatata catttgattt
    74401 tcactttaat aacacaaaaa attgtacatt tagtatacta acatattcct ttattagttt
    74461 tatgtccata aatatcatag ttgcaatatc tatcatattt cttaaacttc tataaagcaa
    74521 aaattgtgcc aaattaataa ttttcttaat tttattctaa agttcctcaa tagtatttac
    74581 agacttagca cttatagctt ataagtcttt atattattaa tctattttta taggttaatt
    74641 gtacaaatca tatatcactt ttacctatta aatgcattat aaaaaattgt atttataaac
    74701 actatttact actcttctaa gtacaaacag tatctacata ctataacctt tcaccattag
    74761 attctattac ttgtttatac cagtcaaaac tctttttctt aatcctagac aagtctccac
    74821 ttccatcatc atacttatcc acgtatataa acccatatct cttggccatc tcaccagtag
    74881 atgcacttac taaatctata catccccatg gagtatatcc aaataaatca acgccatctt
    74941 ctacagcttc cttcatttgc tctatatgtg cttttaaata ctctatacga tagtcatcat
    75001 ttatcactcc attagattct tttttatcat aagctcctaa accattttca actaccatca
    75061 taggtattct atatctatca taaatttcat ttagtgcata tctaagccct tcagggtcta
    75121 tttgccatcc ccattcacta gacttaagat atggattttt cactccacct aatatgttgc
    75181 cacttgtatt atcttcttta gaatcactac ttacacatgt agacatataa taactaaatg
    75241 tataaaaatc tacacaacct tcttttaaaa tttctaaatc tcctttttcc atttttattt
    75301 caatattatt ttctccaaaa tatctattca tataagttgg atattcgcca cgcacttgta
    75361 catctccaca gaaataattc attactctac tatctctttg agttttaact gcatcatctg
    75421 gattacaagt ataaggatac attgttgcaa atatttgcat acatccaact tgataatttg
    75481 aatctatttc atgagctaac ttaacagcct tagcacttgc tacaaattga tgatgtaacc
    75541 cttgaaaacg aagttgaggt atatctactt ggtttataaa atctgtagtc ccttcattta
    75601 atattccttg tgataagtag cctcccatag gcattgtagc tgaatttatt tcattaaatg
    75661 tcagccaata ttttactttt cctttatatc ttttaaatat tgtttcacag taattcatat
    75721 acaagtctat tacatctctt gaaacccatc cattgtattt ctctgttatt gcaaatggta
    75781 tttcatagtg agatattgtt attaatggtt ctatattata ttttaaacat tcatctatca
    75841 cattttcata aaatttaagt cctgcttcat ttggttcttt ctccattcca gttggaaata
    75901 ttctagtcca tgctattgaa aatctaaata ccttaaatcc catttctgca aataaagcta
    75961 tatcttcttt gtatctgtga taaaaatcta ttgcttcatg acttggataa aatgttcctt
    76021 tttctataac tctcgttatt cttttactta ctttttgaga acctccagta cacatatctg
    76081 aacaagaagg acctttccca tctaaattcc atgctccttc acattgattt gctgctgttg
    76141 ctccacccca taaaaaatct tttctaagtg ccataattct acctccaata atttatttat
    76201 agtaacttta ttttaaaata aaaatacata tatataattc ttaattaata gaactctctt
    76261 ttacgctaaa acagttatca atttctgact attatttaca tgcttttgtg tattttctac
    76321 aatatccaca taatcagaat aattagtaac aactactggt gtttctaagc aatatccttc
    76381 ttttgaaata ctttctatgt caaaagttat taatgtctga ccttttttaa tcttatcccc
    76441 ttgattaaca aaagatttga aatatttacc ttccaactga atagtattta accctatatg
    76501 tatcaatagt tcacaaccat tatcagatat aattcctatt gcatgttttg ttggaaataa
    76561 agtcattaca gtcccatcaa atggtgccac tacttttcct tctttaggtg ttattgctac
    76621 accttttccc aatatacctg ttgaaaacgc tgcatcttgt atctgctcca aagcctttac
    76681 ttcacctttt attgggctat atactacttc tcttttgttt ttttctataa cgccttgccc
    76741 attatcatct ttagaaattt ctactatagc atcatctttc caaaaaaata atgttaaaac
    76801 aaatcctact acaatagcta ctattattgc tattatagtt gcataaacac ctttcatatc
    76861 tccagttgtt ggatttatat aattaggtat accaaatatt ccaagtccac ccattacata
    76921 actttttaca ttcattatcc ccattacagc tcctgccaca gcaccaccta cacaactata
    76981 tatgaatggt gtttttcttg gtaaagttat tccatatatt gcaggctctg ttacaccaca
    77041 tatccctgaa ataactgcag gtatacacag ctcttttatc ttcttatctt ttaatttaaa
    77101 gtacattgct gctactactg ctgtttgtgc aaaagatggt acaaatactc ccactaatat
    77161 tgtgtcaaac cccatagtca taaggtttga catagctatt ggtactaatc cccaatgtag
    77221 accaaatatt acaagcactt gccacaataa accagttaat gcaccacata aaattggtga
    77281 aaagttaaat aaagctaaaa atccatttcc aactatatta gaagcatagg tagctatagg
    77341 ccctataacc ataaatccca atggtaaaga aactaataaa actgccattg gtacaaagaa
    77401 attctttact acatctggta ttattttagc aaacactttc tccaacttag ctgctaataa
    77461 tactattaaa attactggta ctactgttga agtgtagttc attgctatta ctggtaatcc
    77521 taagaaagtt atatatactg gtgattcaaa tattgttcca gtaaatagat tgtataaagg
    77581 ttgacctgta gatgctagag tatctaattg aatacctgaa tagcataaaa ctgcacctat
    77641 aagcattcca ataaatggtt ttaatttgaa tttcttagca gctgtatatc caagaattat
    77701 tggcatatac tggaacattg catctccaat tgcatttaac ataatatatg caccatcagt
    77761 ttctccatac aaacccaatg ctgtaaatac tgcattaaat ccttttatca taccagcagc
    77821 acacagaact cctaatattg gttgaaaaac tcctgatatt atgtctataa acttattaag
    77881 taatcctttt ggcgcatctg agtctgaatt atctattgta tctcctccta atccagccaa
    77941 atcgcacaca acttcataaa catctggaac atgattacca ataactactt ggtattgacc
    78001 tgcacttttc attacagtaa ctataccatc catttttttt agcacatcat catttgctat
    78061 tgactcatct tttaatttaa aacgtagcct cgttatacag tgagataaac tgctaatatt
    78121 atcctttcct cctacattcg caatgatttc ttttgatagt tgttcatact ttctcatttt
    78181 ttctcctcca ttttcttttt gaaatatgaa ggtttggcca acttaatgtc accacccaat
    78241 atatataaac ctaattatta ggatttatat ccgacttaat acttttactt accactcttt
    78301 caacgtgaat agttaagtat aatttttcct catctgttaa atcgtagttg tattttttat
    78361 gtataaattc atccaacttt tctatgaatt tataagcatt tttatattta acttttatta
    78421 catttaataa atcatcttca ttattttcat gtaaattatt actaacaatt cgttctgcaa
    78481 aatactttaa gtgagtaata aatctatgat aataaactga atcttcatca aatactattc
    78541 tgtaatggta tttaaccata tttgaaattt cttgtattat ttgtgtaatc tcatatatag
    78601 tttttatact ttgatccatt tgtgcattaa ctatatgcag tgctataaat ccagcttcat
    78661 cttctgatag tctaatttca aatttttttt ctatataatc caatgcctct aaccctattt
    78721 taaattcact cttataaaat ctttttatat cccaaagtaa tacatttttt acacttactc
    78781 cttcacgagc tctttctatt gcagtataca tatggtctgt taaagaaata taaatactat
    78841 catttaatct tttccctagt ttttctttag catataaaat tatttcatct gataattcca
    78901 tatatcttat aggaatatct gctattagtt ctttaaattt atcagatata tttgggtctg
    78961 aaagtttgaa tatcttatca attttatcct ttgatatatg ctctcctgta cgttttttat
    79021 aagctaaacc tctccccata actactattt ccttatgatt ttcatcagtt gtaataatta
    79081 cattattatt gagtattttt tcaataatca ttgtgatgcc ccctttatta gcattaagtt
    79141 aaaataaatc ttttttaatt atttagaata tttaaaatgt aatttattac ataaaaaaaa
    79201 acctatttat tacacattaa atagactccc atgagtcctg agtaataaat aggtttagct
    79261 tgtatttaaa caatcactat ccgtttgtat tttattttaa ttattattta ttatatgtta
    79321 gcaaatttat tttttagtgt caactttttc tcaatatttt aattttaaat aaattatata
    79381 aattgaatct tcaaagtact atttttatca ataaacaaaa taaaaaaggt attactttct
    79441 ttaagtaata cccatttatt tctaatttaa gtggtttttc ttaatctcat caagtagtcc
    79501 atcttctaaa taaatttcta atgcacatcc taccattgcc tttactgctt tgtgaagttt
    79561 atcataagct tcctcagaat ttgcataatt tagaaattct ttttcatgaa catataccat
    79621 tggacttata tctaaggcta tttctgtata catagtaggg caaacttgac ttacattacc
    79681 tatatctgta gaacctactg gaccatcttt accttctaat atatctgtta tacctgcctc
    79741 aatcaaatta ttctttgtta tcttttgaag tactttgtta tttattatgt tgtcaaaaga
    79801 attttcaaag tatctataag aaagcttagc tcctgtcatt aactctgcac cttttgcaca
    79861 gtttataact tttttagtta cttcatctaa ataacttctt tcagcagctc ttacgaaaaa
    79921 cttacaagct gctttttctg gaactatatt tggagcctct cctccatttg aaactatacc
    79981 atgtattcta acatctgatt ttacatgttg tcttagtgca tttatcccag caaaagtaag
    80041 ttgtactgca tctagtgcat tgactcccat atgagggtga ctagctgcat gtgctgatac
    80101 cccttcaaaa ctaaactcta atgaatctat cgccaaagcc ttacagttta tattattaaa
    80161 agcttctata tgcatttgat aacttacatc aacatcatca aaagctcctg ccttaactaa
    80221 atcacatttt cctcctgttg tttcttcagc tggtgttcct attagtacaa tttttccttt
    80281 aaaattttct tttaacttac ttaatactat acaagctcct agtgtagatg ctgcaatcca
    80341 gttatgtcca caagcatgag ctggttcttt attttctcca tatccaggaa gtgcatcata
    80401 ctcagctaaa aatgctatgg taggtccatc attatctcct aattcagctc taaaagcagt
    80461 ctccatatta caatatggat aaactgtatc aaatccatat tccttcattt tttctactaa
    80521 gtattttgat gatatgtatt cttcttcccc taattcagga ttgttaaata taaaattaca
    80581 aacttcttca atttcttttc caagttcatt ctctatctca taagctctct tctttatact
    80641 ctctatcata atttacctcc tactagaatc ctagatataa tcctattgtc aaaaatgcca
    80701 ttacaagaat tgttaatact accattaaag gaattacgaa tctaacccac tttgaccaag
    80761 gaatattggc tactgctagt gctcccatta aaacacctga tgtaggtgtt atcaagttag
    80821 ttacacctat accaaattga taagctgtaa ctatcatttg tcttgataca tctactaagt
    80881 cgccaagtgg tgcaagtaca ggtattgtaa gtgatgcaag ccctgatgct gatggtatta
    80941 aaaatgctat taatccttct attaagaaag ttaaatttat aaatatagtt tttggtaatc
    81001 catttaataa atttgctgca gaatttaaaa ttgtatctat tataaatcca ttttctgcta
    81061 ttattacaat tccacgtgca aatgctatac acaatcctgc tgtcattaaa tctcctgctc
    81121 cacttataaa tgaattaact atatcatctt gtttaagacc tgatgctata cctgatatta
    81181 tacctatagc tgtaaatatc attgcaattt cagttatata ccatcccaac tttaaaactc
    81241 catatatcat aatcgccata cctattgtga aaattgctat taccatggct tctctttttg
    81301 taaattcctt tatatttgta tcactattaa ccattgattc ttgatttagt gatatatcgt
    81361 gtactaaaga ttttttaggg tcttttttaa ctttattggc atacatcata acaaatccta
    81421 tagatatagc catatatatt ataaacataa caactctaaa ctctattcca gaacctggtg
    81481 ctatttgtga taatgcttgt gctattccta cagagaaagg attcgtagta gctgctccaa
    81541 atccagctgt tgctcctata aatactgtgg ccactgctgt caatgaatca tatcccatac
    81601 tggtcataag tggaataaat atcatataaa aaggtagtgt ctcttcactc attccaaacg
    81661 tcgtcccacc tagtccaaat agaatcattg aaatcggtat tattaaaaat tgaaacttct
    81721 tcattttatt tacagtatga gctataacag cttctatagc tcctgtttta ttaactatcc
    81781 caaaagctcc tccaactatt aaaacaaatc caactacttc agcagcatct ataaacccgt
    81841 ttataggtgc tgtaaataca tcagtaattc cttgtggatt tgatggtgct ttttcataag
    81901 ttccagctac aacaactgac cttccgtcta tatctactct ttcaaaattt ccacttggca
    81961 ctatccaagt aagaattgcc attaacacta ttagcaaaaa tattattgta agtgtctgtg
    82021 gcatagtaaa ctttttcttt tttaaactgc tcatttttaa tctccccact ttttaaatta
    82081 aatattttat tattgcatcc ctttatccta ttttgtatag atgtaaaaaa gctcaacatg
    82141 gatacatgtt gagctaaatg tgctaaatac aacatacctg catcttccct ttatcttgtt
    82201 taagatagct ctccatcaaa attcgggata attttgatga cagtactgta cctattaaat
    82261 acagtcccag cactagcttc ggacactagc acttcggcac ttactccttt tatattgcct
    82321 cattggtttc caacctcttc aatattaatc ttagtaaatg caacctctac ctcaatctgt
    82381 ttgttagatg aggtaattct tattaatttt tattaattca aagtaattgt agcataatat
    82441 gtcgagattg taaatatttt cagtataata attcttactt tatgatttca ttccattttt
    82501 cacaaataat tttttctcca tataatttaa atactgtagt atattttaaa tacacacaaa
    82561 ctttccacaa attttaaatt attataatac ctttataata aaaaataaaa gctatgtaaa
    82621 cttatcaatt tacacagctt tatatacatt aatctactcc aagtacagct ttaagctttg
    82681 atgctattgt aataactcgt ggaccaaata taacttgaac tgagtttttc tttttaacaa
    82741 ctccacttgc acccaattca tttacccaga agccatcttc atagaatcca tcaattgaat
    82801 ttagctctac cctaagtcta gttgcacagt ttgtaacatt ttttatatta ttacttcctc
    82861 ctaaaccttc tattatagaa tgtacaagct ttgtatcttt atcatctact tcctcttcta
    82921 ctgcattgtt gtatgctgtt ttaccagcat ctacagattg tctttctcta tattctttct
    82981 tactataaag cttaacttct tctgaacttc ttcctggtgt ttttatatca aacttcttga
    83041 ttgcccatgt aaatattata taagtaacta taaaaaatat tggtatcaaa aataataatg
    83101 gtaacgcatc cactttttgt ggttgtaata aattaggaaa catatttcta aatgattctc
    83161 ccattataga aacattaaac atttctgtaa atacatacgt caatcctgcc agtggtacat
    83221 atgctacaaa atacaataat ggtgcaacaa ataggaatgt atactctatt ggttccgtta
    83281 cccctaccaa catggctgtt actattgctg gtatcaatat acttattgct tttttcttat
    83341 tagcattatc agccaactta tacatagcta aagctgctgc tggtaatatt gcaaaatgta
    83401 ttaataaacg acctgttgtg aagttacgag ttatataaga tagtgtatct gggtctccca
    83461 tttgagctaa tcttatatta ttaacaccct cgtaaattgc tccacctact tccattgttc
    83521 cacctactct tgtatattct atagggaatg caattaagtg atgtatacca aatggtaata
    83581 atgctttatc cattgctcca aaagtaaatg ttcctaataa tccactagaa cctatccaat
    83641 taccaagttt agataatgcc aaccctactg gtggccatat aaagtacatt gctgtaccca
    83701 atactattga tgctataaac atcataatca ttgaaaatct tggacctgag aaaaaagata
    83761 atgcactagg aagttctatg tcaacaaatt tgttatgtac tgcactagct acaaatccag
    83821 ctattatagc tccaaatata ctacaatcat atgaaaagat tcctaagaaa gaaccatata
    83881 aagaacttcg actatatgct tctgcctctc ctaatccaga tgccataaac gcttctgctg
    83941 taactgtatc tgaatttata ccatttgctg ctaacaatgt acttataact gtgtgcattc
    84001 ctataaataa aacaattcct cctaatgcac cccatccttt ttccttttta gataatccaa
    84061 aggctatacc tgtaacaaag aatattggta agtatctcat taccataaat cctaaatcgt
    84121 ttattacttt aaagaataca tttataaatg acccttcttt tattagtccg ctaagcccta
    84181 atgcagaaac gttttccata tttgcaaaag ctgaccctag tcctataaat actcctgcta
    84241 caacaagtaa tataacaggt atcatcattg ctccagaaag tacttgtaat ttatccttca
    84301 tagtattatt tcctccattt ttattgaaat gccaggctat ataatgcata tatatatact
    84361 tctattgctt tgtataatgt atctatactt atattttcat ttgcctgatg tgaatttgga
    84421 ttatccccct ctattgtggg tccaaatgca actccatttt ttaacactct tgcataagat
    84481 gcagctcctt ttgtaaaaag ttcggcttct tttccaaaac cttgtttata tgcatttgat
    84541 aatttattta ttaattcact atctggtttt acatacagta attttaaatc cttatatata
    84601 tcaactatta aattttcttt ttttccaatt tcattaattc tattagttat aaactcccaa
    84661 cttataccct taggatatct aaagtctatt ttcatattca attcattttt ctctaagaag
    84721 atactcatta tacatattgt agaaactccc atatctacat cttctttata tatccctaat
    84781 ttttttccat gattatcatc tgtaaagtat gaatttaaaa tatcccttat tataacgcct
    84841 ttatcattta gttttttaat tttctctaaa tcttttgcta aactaaatgc acagttatat
    84901 gacctgtgtg gatttctcga taaagccctt tctcctgtat atcttactaa tactttacct
    84961 tcttctagtt cttctatctc tgtataataa gctaatgatt ctactaaatc tttcttatca
    85021 ttagttttaa aaacagcctc aattttgtca catacaaatc catcttcttt gtttgacttt
    85081 atatcaacta aattgtgatt tctaaattta tctttatcta ttttctttct tagattgaag
    85141 tataaaatac ctttttctcc atttactatt gggaagtttc catctggaga aaatgcaaat
    85201 tttggctgtt cattgacact aaagtaatgc tccatacatt cccaagtcgt ctcttcagct
    85261 ccacccacta tcaatctaat ctttctcttc ggcttttcat taagttctct taagaaaagt
    85321 aatgcatata aaatccctat caaaggtcct ttgttgtcat taactcctct accataaaga
    85381 tagttatctt tttgacatac tttaaaaggt ttactcttcc aaagttcttt attatatatt
    85441 ggcaccacat ctatatgatt aagcacccct actacttctt ctccttctcc atattctata
    85501 tgaattgcat atccatcaaa gtcttttaca acaaaatctt tgtcttttgc tatttgaata
    85561 agcttatcga aggcatttct tatttctatc ccaaatggtt gatttatatc tgttgtactt
    85621 tcatctctaa ttgaaggtat ttcaactaaa cttctaatat catttatgat attttcttga
    85681 ttggatttta aataatcaat aattagttct ttgtttacta tcatcttaat tatttatcac
    85741 ccctttatat taattttaca aagcatttca gttcatatct acattataaa ttttgaatat
    85801 tattttttca atatttcaaa tacttctcta agttaccata atgatacggt aaacaatcaa
    85861 cagattatga caaaatcata ctatacctat tactaatatt ttaacttatc tattacgtct
    85921 tttttaatgt aagtttattc caaaaataca taaaaaaaga tgtagcctta gctacacctt
    85981 cttatatcta ttcaacttcc attattatgc tattaatatc tacatttcca ggttctatcc
    86041 tatcttttac tgttctctta acagaatcag catcatccat tataactaca ggagttatta
    86101 tatttaaatc atttgacgtt ataaaatcta aatctacttc cattattaaa tctttagctt
    86161 ttaccttatc tcctgccttt accttaacat caaacggctt tccttctagt gacattgtct
    86221 ctaaacctac atgtattaat atatttgtat tatcattact cttaatcatt attgcatgct
    86281 ttgtatcaaa tacattgact atttcaccat caacaggaga atataactta ccttcacttg
    86341 gtattattgc tactccatct cccatcatct tttgggcaaa aactgcatct ggaacatctt
    86401 ctaagttcac taaatttccc ttaaaagggc tatatatttt ctcaatctta ttttcttttt
    86461 tcttaaatat attaaacata acacactctc cacattataa aattttatga taatattttt
    86521 cttaaagctt ttgctacacc atcatttaca ttagtatcag ttacaaaatc tgccatagat
    86581 tttacttcat ctgtagcatt tcccatagca ataccaagac ctgcaaattt aatcatggat
    86641 atatcatttt cattatcacc tatacaaata acttctttgc tatctatacc taatatatca
    86701 caaaattttt taactgcaat accttttgaa gtacctttac tcataacttc aaagtttatc
    86761 tttccagaac ttactacttc taaatcttct tgttttttaa attcttcctt tgcttctctc
    86821 aaagaatcta cgttttctga gaaaagtata cattttaaaa tttcattatc agctttttct
    86881 aataaagttt cacaacttgc attttctatt atttcaattc tgtcttcttc tttattttta
    86941 ctatttatta atctatatgg atgttcttca cctatttcat tgttggatat aactatttta
    87001 cagcctttaa aatgtttgct taaattatac ttttcaccta ttgtatagat tttctttaga
    87061 gcttctttgc tcaaaacctt cttatactca tatcccagta atttaaaata tgtcccatta
    87121 gttgatataa tatatatatc atcccctaaa acacttgtaa aatatttcat agcattataa
    87181 ggtcttcccg taactaaggc taccttgata cccttttcca tgacttcttt tagtgcttta
    87241 atattttctt ctgatacttc aaatccttta cccatcaaag taccatccat atcagtacaa
    87301 attaatttat atcgcatttg tatcacatcc tagtaagatt tttctaatat ttcaacaagg
    87361 tcttctttct ttccaaaagg taaaaatcct aaaactggac agcttgttat ttgttctaat
    87421 tgttcctttg ttacattaaa ctcagacatt tttgtcttaa gtcccactct ctttaaaaaa
    87481 ctttctattt catttcctaa agttttagct gcttcatcat cttccacttt ttctaattct
    87541 tggtttagca ttctcgctac tttggcaaat ttctctatat tatccttata gaacttttct
    87601 gcaaattttg ggaacactat agccaaagcc tcaccatgag gaatatgtgt aactcctcct
    87661 attatttcac ttagtggatg tggtgctgct gctccagcat ttgccagtga acttcctcct
    87721 aatgtatctg ctactgctaa ctttgttctg tattctatat tatttttatc ttccattact
    87781 ttaggtagat agttaatgac taattccata gatttttcag acattatctc tgtaaaatca
    87841 ttagcatttg gatttatata actttcaaat gcatgagtaa aagcatcaaa tgctgttgat
    87901 gcagtaattc tctctggcag agttaacata agctctgggt caactataca ttcttttgag
    87961 aaacaatttt gatgaaatat tgtatttttc tcgcttcctc tcgatattac tgctgcttgt
    88021 gtaacttggc ttcctgttcc agaagtagtt gatacagcta ttaatggtaa ttctttttca
    88081 cttaccttat cgtatatttt aaatggattt gtatatgtac taaacatata atcccaatct
    88141 atcttttcta aaccaaaagt caatgctaat acttttgcag tatctatact tgaacctcct
    88201 ccaacagcta aaacaacatc tacagattct tttttagcta attcaaaccc ttcatttatt
    88261 aattctacag ttgggtttgg ctctactcta tcaaagtgta caacttctat acctttttct
    88321 attaaattca atgtaactct tttatataac ttgtctaatg gctctacatt tggagtagta
    88381 actaacaaac atttctttcc atattttcct attattctag gtaattcact taaagttcct
    88441 tgtccaaaat ttattcttga tggttgataa aagttaatca tatttttcct cccttaaatt
    88501 attgccttca tattcaaatt atacatatca taggattttt aaggcaatac cttcactgtt
    88561 aactcttatt tactaaagct tatggcaatt attagacaat caatgtttta ttattaccat
    88621 atcattatgt aaattttatt aagtacccat gttataattt tataatcaat cttattgtat
    88681 aattgactta ataataaaaa tagagtatat acactttttt atgacaaata gcttaaagga
    88741 gaattaaatt atgaaatatt tgatagacag tgctaatctt gatgaaattc aaaagtgttt
    88801 aaagtatgga tttaagggaa taacagctaa tccatctatg tatcttaaag agaaagtaaa
    88861 cttccatgaa tttattgaga catgtgctaa tttaaatcca gaaatattaa ctgctgaagt
    88921 cattggaaat aatttatacg aattaattaa ttcatgtgat aagatattaa atataaataa
    88981 aaacactata ataaaaataa atttctctga agttggctta gaacttataa acatattaaa
    89041 tagtaaaggt gtaaaaactg catgtacctt gattttcaat gtaaatcaag catcattagc
    89101 tataaatgca ggtgctgatt acctattccc ttttataggt agaaatgatg aaaatgggaa
    89161 tgatggtata aaaaacctta cagaaatatg taaccttata tcaataaatg gatataatac
    89221 taaagttgtt gcagcttcta ttaaaaatgt attccactta actcaagcat ctctttgtgg
    89281 atgtgattat gcagctgtaa catatgattt atttaaaaaa gcttctttta accagcttac
    89341 aatagatggt gccaatactt ttgaaagaga ttggtccaag gttaataaat agtaactaag
    89401 atttaggagg gtttgcattg aacaaaagat tattagatat tgctgaatta ttactcaaca
    89461 gctcagacta tattactgta gatactattg ccgaagaatt aaaagttagt aataaaacta
    89521 ttcgtaatga ccttgttatt ttagatgaat ggcttttaga gtttaattta tccctagata
    89581 aaaaaactgg ttcaggggtt attattctag gtaatgaaga tataaaactt aaagttatta
    89641 gagatatcaa tgataaatca aattgtatat atgcatactc tcctgaagat agaaaaaggt
    89701 atattctaag taaattattt attaaaaatt ctaagtttag gattcgtgat atttgcaatg
    89761 aactacatgt tagtagagct actgtgcata aagacttggt agttattcaa aattttttgc
    89821 aaaactttaa agtgactcta gttagaaaaa ccaataatgg agtatattta gagggaaaag
    89881 agaaagatat tcgaaaagca atttttgaac ttgctacggt taataaaagt tatactgaac
    89941 ttaaagaaat attattctcg aaatctaatg aatgcaaaga taccccttca acaaaaatat
    90001 ttaaggagct atttaactat gattttgaga aattatctca aatcactcta cacaccttac
    90061 aagtagaaaa aagtaacctt agtgatgagt attatataaa cttcttaata catatagcta
    90121 tatgtattaa aagaatttca attaaaagat atattaactt atctgaaggt ttttttagag
    90181 aattattaga acatgaatac tttgaaaaat caaaaatttt atgtgctaac ctaagtgaag
    90241 cttttgacgt agaatttatt gatgaagagg tctgttatat ccttcttcat atagaaggat
    90301 tacttaaatc aataaagaaa actactactc ttgaacctct taaaaatgaa gaaattacag
    90361 agtataatct atctgaagca atagctgttc attggggaag tatactaaat ttaaacttaa
    90421 aggatgattt aatattaata aagtctcttg ctaatcacct taaatcagtt ctacacagaa
    90481 taaactatgg gtttactatt acaaatccca tattaaatga tataaagaga acatttcctt
    90541 atacttataa ggctgctaaa gagtctaata ctgttatcaa acagttgatg aattatgaag
    90601 tcaatgatga cgaaatagga tatcttgctt tatatttaat atcagcaata gatagaagca
    90661 aatctcccct taatactatt ttaatatgtc actgtagtga tggtgtatct aatttattag
    90721 tccaaaagtt aagttttgaa tttaatcaga ttaatatagt taaatctata cctctatctt
    90781 ctatttcatt tacgaacttt gatgatgtgg acttaatact aaccactgct cctgtagact
    90841 ttgaacataa tgctgaactg ataaatataa atgctctttt aagtaagaat gatatttcta
    90901 gacttagtac aattataaaa aaactatatt ctgaaaaaaa taaaatatta tcttataaat
    90961 aaacaaaaat aggcttgtct caacatagag ataaacctat ttttcattgt ctaaatgata
    91021 aaaatatatt tgatttcata gaaaaagtgc ctcatgaact aaaaaattca ttttgagaca
    91081 cctccatttt ttatatttaa gctttttatt taagctttta tattttttaa acttttatat
    91141 ttaaagtaaa ttttattatt tttattgagc acaagcatta tttatattat taatttcttc
    91201 agtattctta ccaaactttg tagttacaaa tcctattgtt tttattatga gtaataaaga
    91261 tatcaatgaa tatatagata tcataaaatt cttacttatt attccagacg ctactattat
    91321 aaatccatct agcataaata atataactgg caacttcaga aacttaatta ccttattaat
    91381 aagcattgca actaaatcag ttccaccagt actacagccc cttattattg ctatccctat
    91441 agcagttcct accaataacc cacctatcac tcctgctact aatagattgt cagttatgtg
    91501 agtttgtggt attactttta agaataatgg gcccataaga gttatatata atgtttttat
    91561 tccaaaacct ttccctaaaa ataataatcc cattactaaa agtggcatag atattcctaa
    91621 tgatatattc tcaacaggca ttgataagaa tgtgctaagt acgactgata atcctgttat
    91681 ccctcctgga gctaatgtat gttctgcaaa gaaaaaatta actgctaatg ccattaaaaa
    91741 tgctgatatt gttatcagta aataatcttt tatcatttct tttttcattt aataacctcc
    91801 tatgattata ttatttcagt ataaaaaatc aattaaatta gtctagcttc ctgtagtttt
    91861 tcataaaatt aatgcttcct taaaacatta agaaagcatc tcttttatca tagtttatta
    91921 tcttattcta aaccaaactt tgtagctgct ttatctatag cttttctaca attcttaaca
    91981 cctgctgtta taccatcttt atccttgaat attgctgaag ataatattac aacgtctgga
    92041 ttacattcta ttaatggctc catattgtct gctcttagtc caccatctat tgctaattca
    92101 cacttaggat tcttttcgtc tatcattttt ctagctcttt ttactaaatc aacagcactc
    92161 tttctccatc cccagttatc ttttccatca gtttcatcaa caccatgaac gactatttgc
    92221 aatctatcta tatcatatat agcttcatca acaaaacata atggtgtgta acatccaatt
    92281 gttaatccta ctttcatacc aaattctcta cagtaattta ttatgtatgc aagaggagca
    92341 cctaaaaaat gttctgctgg tattatcaac aagttacatc ctgctgctgc tattttttct
    92401 ataaataatc tatcacaatc tcttgtgtat atatggcatt ctattggttt atctgtcact
    92461 ggtcttattg cttctattat ttgatgacca cccataagtt gcatattttt taagtcatgc
    92521 atatctgctg catctgaatg cacgtagtct acacctgcat ccattgcttc tttaactacg
    92581 gctgatatat gaccgtaatt tacatgtgct aatcctgctg ctatttttat gtgtttcata
    92641 tttgtatacc tccatatttt actttaatta gtattaaata ttagtttttg atattttttt
    92701 aatatttttt aatccagtat tacttttatt tagcattact tttattgctg tatatatttc
    92761 ttttatgaac ttattctgct tttgttaact gtgaacttat tttgctttgt aaattaatat
    92821 tacactgata tatttttttt cacaacactt tgactactcc ttaaaagtac ctttatattg
    92881 tggtaaatta tagacattaa ttgtatataa aaagttagtt ttttaccaca ttcttatggc
    92941 atttattgtc tatactaact caattgatat agctagttca tttaatatat aatcagacta
    93001 taaatataaa tttactcgat aaaaagtacc attcataaca atattaatga aagggagatg
    93061 taaaatgaga aactgtatta ttgcccaatc tggaggccct acagctgtta tcaatgcttc
    93121 tgcagttggt atttatgaaa aaaatttaga aactaaatac tttgataaag tatattttgg
    93181 tatcaatggg attgaaggta tattaaacaa aaatataata gattcagact ccttaaacaa
    93241 agataatgta ttaaatttaa agcaaacacc ttcgtctggt cttggttctt gtagatacaa
    93301 actggctgat tataaaataa attcttatga ttatgataga gttataaata tactagatga
    93361 atatgaaata gatacattat tttatatagg cggaaatgat tctatggaca cagtgatgaa
    93421 attttctcaa tactgcaaaa acactacttg taaaataaaa tttataggta ttcctaaaac
    93481 aatagataat gatttattag gaactgacaa ctgtcctgga tttggttctg ctgcaaagct
    93541 tatttctaca ctaataatgg aaacatactt agatttttct atatacaaaa ataatggtat
    93601 atttatagta gaaactatgg gtagagatac tggatggtta gcagcttctt cttcactagc
    93661 tagacttaat gatactccac ttgttgattt aatatacctt ccagaaattg atttctatga
    93721 agataagttt atagaagatg ttagaaaaat atttaaagaa aaaaataagg cttatatagt
    93781 tgcgtcagaa ggtataaggg ataaatacgg caactttata tgcgaacaaa aaacttctgc
    93841 tcatgataaa tttggtcatt cccaattagg tggagtaagc aactatctaa agaatcttat
    93901 agtatcatca tcaattacaa caagagtaaa aaccttagaa cttggtgtaa tacaaagatg
    93961 tgctatgcat ttagcttcag atactgattt aaaacaagca gctgaagttg gtgcatatgg
    94021 gatagaacta tctaaaaaag gatatacagg agttatggct atcattaata gaacatgcaa
    94081 taatccttat aagtatgaag ttagtcatac tgatatttct aaaatagcta acaagacaaa
    94141 atattttcct aaagagtgga taaatgaaga atgtaattat ataactgatg aagccctaaa
    94201 ttatctatat ccacttattc aaggtaaacc agatatcaaa tataaaaatg gactacctta
    94261 tttttcaatt atttactagg aaattattat aatttgatat acactcaatt ctatcgctct
    94321 taaataccta agtggctgtt aaataaaatt ataaattgtt atatgacagt cacttaatcg
    94381 tttaattatt taactgttta gttttttaat tttttaatct tttttaatac taatacgatt
    94441 tgttgtaata atatctcaca cccattttca ttttggatag attataatta gttagacaat
    94501 aaatattttg tcatgatatt attatatata gtgatacaaa tagaaatact tttatcatgg
    94561 ctagaaaaac aaagattaca caaaggattt aaaaatcaaa caacttcaat taaaataaat
    94621 ggttaaaata acttctaaat caactactat aaacaataaa agaacataaa gtagttaagt
    94681 ctacaattat aaaattagta agactataat aacttaaata aaattaaagt taacaaagac
    94741 tattaaagtt agcaaatatt cctctaccta aataattgct ttttataaag agttatttat
    94801 tttaattgaa tttaattgaa atacgatttt aactagaaca atagattaat gtaatattta
    94861 atataaaata attataataa ttgaaaagga agtaatctat gatgaaaata gcagtcataa
    94921 caaccgaatt tttaaaagag tttgtagata attctataaa aaagttaaat attaatgcag
    94981 aaattgaaat atatatctat agagattttt ctcatgttgg agatttatat ttagaaatag
    95041 aagataggtt tgatggattt gcagttagtg gccccatccc caaaaaagct attacaaaaa
    95101 aggctggaac tattaaaaaa cctctagttg attttggtac tgacttacaa agttactatg
    95161 atatgtttct aaagcttatc tttaaatata atacattaga tttttctaga gcgtactttg
    95221 acttaacaga ctgggcagat aatccaaaag atatatcata ttatttatca aatggcacat
    95281 ttggagactt aatggatagt attgatgaaa atgcatctaa aatgagttta tctgacatag
    95341 caaaacttga aaaaaagatt gcaaaaaaac atattaatct atggaatgaa gggaaaatcg
    95401 atttttctac tactcgtttt agtagtattg ttcctatgtt acaaaatgca ggagtaaact
    95461 ttcatttcat ataccctgat atagatttat taaaaaatac ttttaataac ttaataaaag
    95521 atattcattt acatagaatg aagggaaatc aaccaagtgt aatatatata acagttaaag
    95581 atacaaatta tgatgactct actctagacc aagtttataa aatattaaat agtattaaaa
    95641 aagataaatt aaccgatttt ataattgaaa aaaatagtaa ttcttttaaa attttcacta
    95701 aatgtgaaac gattaaatca ttaactaaaa attttactgc atgttatata aaagaatcta
    95761 ttgaaaatag tacaaatatt aaagtatgtg ttggatatgg aattggtaat gatataaagc
    95821 aagctatgtc tagtgccata agtgctaata aggaatctaa aataaatcat ttaaattaca
    95881 gtttcttagt caacgaaaat tatgagacaa taggaccttt actgtgtgat aagttactta
    95941 ctgtttcaaa taaagtaact ccacatataa atacaattgc caaaagttct aaattgtcta
    96001 ctcttactat tcaaaagatt atatctgtta ctgaaattct acaaagagat gaagttactc
    96061 ctaaggaatt atcttcatgt ttaaatgtaa cagttagaac tgctaataga tttctaagta
    96121 gtctcttaaa gtctggaaac gctactatat tatatgaaaa acaaaactca acaaaaggta
    96181 gacctgaaag agtatacaaa ttatttatat cagaaaataa atattaaaat ccaaaatgca
    96241 taaaaatatt ttatcatcta atattaagta aaattatata tgactttcta aaaggtatat
    96301 ctttgcatct ttttaagata taccttttat aatatttaat aatattttat gttattatct
    96361 actaaaatta ttttctaacc attttactgc acaatgagca aataaagctg aaccataaac
    96421 taatccctct tcattaaaaa ttgctttagg attatgcata ccaaaattat atccctgact
    96481 aatacttccc attccaatcc ataaaaatac tcctggaacc cttagtaaaa tctctgaaaa
    96541 atcttctgaa cccattgcag atggaaagtc tattacattt tcatttccta taacttcttt
    96601 aacataagat acaatctcat ctcctacatc caaatcattt ataactgcag gagtccccat
    96661 tttaaattcc actttagcat ttcctccaaa tgatttagct attcctgtag atatttcaat
    96721 aattctattt tttaattttt ctctaacaga ttggtcaaat gttcttaaag tacctgacat
    96781 agatgcttta tttggtatag catttggtac gcttcctgca ttaaacatac caatagttaa
    96841 aactacaggc tctttctgag gtttttctct tgaaagtata gtgtttaatg ctatttgtat
    96901 atgtgacatt atgtttattg ggtccactcc aaattcaggg cttgctccat gagttgcttt
    96961 tccttctact gttatttcaa atatatctgc agatgccata gctggaccac gtgaataagc
    97021 tacttgacct gtgttaagaa atttacccac catactgtga aatgccatag ctgcatcgac
    97081 ctgaggattt tctaatatac catcatcaat cattgatttt gcacctctgg tagtctcttc
    97141 atctggttca aatacaaact ttactctacc tttaagtaag tgcttattat ccataagtat
    97201 tttagctgct cctaagagca ttgctgtgtg attatcgtgt ccacaactat gagatgcatc
    97261 tttattctta cttttaaaag gtaaatccgt ctcctccata ataggaagtg catccatatc
    97321 tgcccttaat aataaggtct ttccaccatt tttactgtct aaaacagcta ctattccatt
    97381 attagacgtc aatttcggag aatatcccat tttttctaaa gtactggtaa caaaggttac
    97441 tgttttcggt agattgcaac caatttcggg attttcatgt aaatatcttc tccatctaat
    97501 aatttcccct tctattgact gcgcttcttt aaaaaaattt ttcatattcc ttcctcctaa
    97561 tcagatagtc agcaaaatct cactttcttt tagtaatgaa atgatgctga tataaaaatt
    97621 ataattttat atattaaatt tcatgtcttt ttaaggagtt ggaatatcat ctggaatagg
    97681 acatttatat gttttaccat tcatagattt atcaaattct tcttttgcct ttttagctat
    97741 ctctggatta tttaatattt tagctccaaa catagccata atctttgatg catatatcat
    97801 acctttttct cctatagaac ttcctgcaca agatgtaaac tgccagctat gacctggtgc
    97861 tcctagattc gtacaccctg taaaaaagta tgctgtcgga actatatgca ttacatctcc
    97921 aatatcagta gagccataac tattaaagtt tgtaacattt cctccaccat aatatagatg
    97981 agttccttct ggcaaattat atttacttat catagcctta tattgttgtg ggctttgtct
    98041 atctaattca gctgcaaaat ccaattcctc tcgagtccaa ggctcttgtt taatctcatt
    98101 catacattct gatacaagat ttgctaaaac atgattgttt aaagtattat aacaccctcc
    98161 taaaaactct acttcaactt cagtttcagt catcattgca gctccttttg ctacctttac
    98221 aagtctttca tatgtacttt ctacagcttc tctacttaaa gctcttgtat aataccatac
    98281 tgatgcttta tcaggaacta tgttgggtgc tactcctcca tctgtaattg tataatgaat
    98341 ccttacatca gaagtaacat gttctctcaa ataattagct cccacattag taagttccac
    98401 agcatctagt gcacttcttc cattttgagg gtctgagcct gcatgtgcag tctttccctt
    98461 aaagtgaaac tttacagagt taacagctgt tgaagtacca attgtagctt cactaatttt
    98521 atttggatga aaatttatag ctaagtctaa cccttcaaac gctccacctc tagccataaa
    98581 tcctttacct gttaattgtt cttctcctgg acatgcataa aatactatag tcccacttaa
    98641 gttattttct atcatctctc ttttaagccc tactactgcc cctacatgtg ctgtacataa
    98701 taaattatgc ccacatccat gaccatatgc acccaattca aatgcttctt gttttgttga
    98761 aactttttga tttaaaccag gtaatgcatc aaattctccc ataaaaccta taactggttt
    98821 acctgaacca aaactagctc taatagccgt ggctaaacct cctacaccta cttccacatc
    98881 aaatccttca cttcttagaa agtttgctgt attttcacat gctttaaatt ctttaaatgc
    98941 tttttctgga ttttcccata ttttcttact taaatcatca agtttgaatc tttttttatc
    99001 tatctcattt atagatatac ttcctatcat tttctattcc tcctataaat ctatttacta
    99061 tcaaccaaat ataattggac ctattatact agcaaatgcc actgatgcaa tggttacagt
    99121 aacaaatcct cctataatca tctttggtaa taaataatct gttgcccttt gtttttcttc
    99181 ttcagttcct tccatagcat caataccttc attggaaatt atctgtgttg caggataagc
    99241 tagcatacaa gttacaccaa ttgcagctga cattcttgga gaatatccca atagttttcc
    99301 tacaattgca gtaaatagta ttataaatac agagcctaca acaagtattc ctatagttgg
    99361 aataatcatc ccaaacaatg ctgttggagt taccttagca agtcctccag gtaacatcaa
    99421 catacaacca aacattataa ttccattaga ttgagattta tctaaaattc ctttttctaa
    99481 aaaacctatt cgtgtaaaaa tcaaccctac taacaaacat gctatgttgg gatttaaata
    99541 atagtttgca ggggtaaatc ctggtattaa agtagccaat cctacaaaat taccaatcat
    99601 agcaacaaat gaaagctttg caagatatac taaagtagat gattttttac ctaaatcttc
    99661 tttaaaaatt ctcatacttg gaagtttaaa attacttttt gactcatctt tcaaaaaatc
    99721 cccgttatct cttttaaatt ttaattcttt atttatacaa tatgtagtta tcggaatgcc
    99781 aaagaacttt tgaaatgata atactagaat tacaaatgca gcaagttcag gtctatttgc
    99841 agcttctgca acagttgtta cgataatacc agcaacagta gaacccgcta ttggaggtgc
    99901 tgctattaaa gcatactctc taccaaataa catactaccc actgttaaac agccaacccc
    99961 tattcctaca atacctacta atgcaattac aaccgttttc cattcatgac ataagtcttc
   100021 aagatttata agtgttccta agttagttat taataaagct ataccaaagt tgctcattgc
   100081 agctaatatc cctgatgctc ctgtaatgtc ttttggtaaa atatttgtcc aaaatcctag
   100141 taaaaatata atacatacaa ataacaatgt tgaaattgca ccttttgttt tcttagataa
   100201 aaactcacta aaagcataaa tcattacaca tacagtaaag caagtaagtg gattccaaaa
   100261 attttccatt gttgtttcct cctaaatata ataatttttt atcaataaaa caataattat
   100321 aaaatgtata ttatgcagtt attcttaact acatatggta tagcttgata ttttttgatg
   100381 atattatata cgtcctaaat tattcctaaa atatctaaat aaatataact agagttaact
   100441 ctctaaatat taactatagt tatcaactta ctagatttct ttttgatttt tactttctac
   100501 ataattttac gagttagaat tgtacttcaa ctattctcta tattagtata catgttggaa
   100561 gacttatatt tatttaaata ttagatatag aatatatttt tataaacgtc ttaaattatt
   100621 cttaaaatat ctaaaacgaa ataataatat acccattaaa ccaatattat cagaatatac
   100681 ttcactttaa gtcttcttta tatagaaatt ttatctatta gtgcatcccc tcccttgtaa
   100741 attagactat ttctaagcga atttagatat cttattccta gagactatta ctaaaaacaa
   100801 aaattattta ttatattaaa tcaatgataa gccatacttt aaaattcttt ctatacaagt
   100861 ataatttatc atataatgac atctatacct ttatctttat agtagtccta aattattctt
   100921 aaattgacaa taaaaataat ttcactattt ataaaaatac ttgtttttat attgtcaaac
   100981 tattcttaat atagattata attttaaatc ttttctttgt caatatattc tgacattttt
   101041 ccagaaaatt tataaagtta tatagtgagt aaatcatact atttttatat aatgagtaaa
   101101 ttatactatg aatatgtcta aatatttact taagtataaa aataaaaaat gtgtattctc
   101161 ctttttatag taattttaat tgccattatt tttaagaaga atacacactt tactttaaag
   101221 accctatact ctattttaaa tgctttacta gacactaatt aacattagtt cctaacttct
   101281 atttatctta ttcctaccct actactatat ccgtagaaaa atctaaaact tctccattag
   101341 attttattac ttctttgtac caatcaaatg attttttctt atatctctta aaacttcctt
   101401 tgccttcatc atctaagtca acatagataa atccatatct cttactcatc tgacctgtag
   101461 ttgcactgac taaatcaatt ggtccccaca tcaaatatcc aaaacattca acattatctt
   101521 cttcaattgc agacttcatt tgagatagat gcttacttaa atattcaatt ctataatcat
   101581 catttatagt tccatcttct tcgattttat catatgcccc taaaccattt tctgtaatta
   101641 agataggtaa ttgatacttt ctgtaaatat agttcaaggt aaatcttaaa cctatagggt
   101701 ctattgccca cccccactta ctttgttcca aatatggatt ttgaatccca ccaaataaag
   101761 atttatcacc tgataaattt tcttttggag tagatacact tgaaaaataa taattaagtc
   101821 ctataaaatc taacttacct tctttaaatg cttttttgtc ttcatcagtc acttcaatag
   101881 ttatattatt tttttcatat tcttttaatt tatattgtgg aaacttccca ttgcacattg
   101941 catcaatttg ataataatca cggtcattat ctaaaaatgc atttaacaca ttactaggat
   102001 tacaattgta tggataaatt ggatttagtc caaatacaca tccaatttta ttgttgggat
   102061 tgatttctct agccaacttt gcaaccttta cacccgccaa agtcatatta taccctacat
   102121 ttgccaatgt ttgaacctta ttttctattt cactatactt aatacctgct atcatataag
   102181 taaaaatatc cgagtgctct gtttgagggt caatatggtt catctcatta aatgtaaccc
   102241 agtactttac cttatcatca aatcttctta ttacagtctc actgtacttt aaatacaaat
   102301 ctataagttt tctgttattc catgaaccat atttatgtac taaattcata ggtaattcaa
   102361 aatgatatag tgttacaata ggttctatat tattttctat taatgtatct atcagacctt
   102421 catagtattt aatccctaat tcattaggat tttcatcatc tccatttgga aaaattcttg
   102481 accaatctat agatattctt aatgcactaa atcccatttc tttaaataaa gctatatctt
   102541 ctttatatct attataaaaa tctattccat tatgagatgg ataatctaat ttttcttcta
   102601 ttttatcagt aattactctt ggcgtttcat aagagccctt agttacaaag tccataattg
   102661 caggtccttt gttatcacta tcccatgaac cttcacattg atgggctgca atacttcctc
   102721 cccagaaaaa tgtatcttta atattcatga attttccctc ctaaaattta tactattaca
   102781 gttaataatt cttctgattc atcatttgat gagattacat ctaaataatc gctagtattt
   102841 gtaactacag ttattatagt agaatcaaag ccttcctcta taattttatc agattcaaat
   102901 actgctaaag catctccttt tttaaccctt tgattttgtg ttacaagact ttcaaagaat
   102961 tttccatcta agtttacagt atctatccca atatgaatta atatttctaa tccttcatca
   103021 gtcactatac catatgcatg tttagttgga aatactatag ttatagttcc atctacagga
   103081 gatataacag ttgattttga ttcactaggt ataactccaa cccctttacc taatgctcca
   103141 gaggaaaatg ctttgtcatt aacttcccca agtgcaatta cctgaccttt tgcaacattt
   103201 ccaatactaa tagttcttga attgttctcg ttgattatta gttctaattc tttttcatta
   103261 tcacccttaa cttcttcttt ttcatctgaa ggtattccta gtaaatagga agctgctgtt
   103321 gctgctacaa atgatactac tacacttatt atcataaatg taaagttaga tacctctcct
   103381 ccaacaagat acgttggtaa tgcagctaat ccccaaacca ttccatatgt tttaacttga
   103441 gctaaacctg ctattaaacc acctatacct ccacctatca ttactgctac aaatggtctt
   103501 ctatatttca taaacacacc aaacactgaa ggttctgtaa ctcccataag tgcactaaaa
   103561 cttactgtac caaatagttg tttttgttct ttattcctag tttttaagaa atatccaaac
   103621 attgcaccac aaactgcaat atcagatatt gttgcagcgc ccataaaaat tgggtcatac
   103681 cccaatgttg tcacagaatt taaagatata ggcatagtaa agtttgctgc accaaaaact
   103741 attaagagtg gttgtaaagc tgcatacagt gcaacaacac tccaattacc caatgtatca
   103801 attaaaaaca tacatgcata gtttaatcca tcaccaatcc acataccaat aggtccaaat
   103861 acagttaatg taactgatag agttattatt aaagataaca ctggaactaa aaaatagtgt
   103921 aatgctttag gtaatatttt tttcaaacct tcaattataa ttcccattgc ccatactcct
   103981 aaaagtattg gaataaaact gtttgcataa gttgtagcct gtaaatttat accaaataaa
   104041 cttaatcctt ctacaccatc tattgatgaa gataataacg taactgctaa cactactgct
   104101 atatagggat ttacattaag tctttttgct gatgctattg caattaatac tggtaagaag
   104161 tgaaatgtag cacttcttaa tgtatctaat atttgatatg taggactgtc actctgaagt
   104221 atgccagaca tatttaaaag tgctaatata cttgcaagta taccagctgc aagtagtact
   104281 tcaattactg aagtcatagt ctctgagact accacaaaga tggaattaaa tatacctttg
   104341 atacctctaa ttcccttttt tctttcactt tttatacttg attcacttga acttaaacct
   104401 atcatagaca taaactcgtt atatacatct acaacatgag tacctattat aatttgataa
   104461 gcaacatcat tagaaactac atcaattact ccttttaatt ttttaatttc ttctgtttga
   104521 gcgatactcc tatcatttaa agtaaatctt aaacgagtaa cacaatgcgc taccgacttt
   104581 atattttctt ttccccctat aagttttatt atattttcat ttaaatcttt atatttcatc
   104641 tgattttgcc tccagtcttt gagtcaccct atttatatgc aacattaaat aagtttcttc
   104701 acttatagat atatcgacat taaattgtga ttttatatat tttcttatct tttgaacact
   104761 tccaaatgac tttggataaa gttgacttac ttgtttatat aaatctatag aattatcttc
   104821 atctattgaa gcttcatccg acataattct ttggataaag tactgtagat gagtagtaaa
   104881 tctcatataa tttgttgaag tttcatctag ctctacatta aaatgatatt ttattataga
   104941 aactatatct gctaaagttc tcaactctac aattgtacta tcatgagact ctttatttac
   105001 ctccatattt acaaaatgaa gtgctattga tactgcctca tcatcaggaa gattaattcc
   105061 cttactatca ccaattaatt ttagtgcatg cattccaatt tcaaaatgct ttggataaaa
   105121 tcttttaaca ttccatacca aaggactttt tataaattga ttcttttcac atcttttaag
   105181 taaaaactct aaatggtcta gtaaggttaa gcttagataa tcacttgcct ttatatttaa
   105241 agctttctca ccatattcaa ttatttcatt aataagaact atattattgg agtctgagtt
   105301 ttgtagtaga taactaaagt gttctagcat atcgtatgaa tctagtatat atgttctctc
   105361 tatttcattt tcatttatta cttgtcccac tcttttttta aagccaattc ctttaacaaa
   105421 tacaataatt tcatttttac ctctttttac taaggctaca ttattattta aaatctgaat
   105481 tattttcata tattcctcct ttcaataaaa agaactcaag catatatgta tagagtatcc
   105541 ctctattttt cacatatata cttgagttct gcctgctaat cagtaacata ctcaaaatta
   105601 tgactacgtc gccataatta aaattctttt ttgtttaatt tcatattcta tatgttatac
   105661 tatccatata aatctgtcaa cggtttccta gatatttttt tattctataa ctacaagctc
   105721 tgttatgcga ttatctgaca aggtttatat actaaattga tactatttta ccgtcactaa
   105781 tatttataat attgtctgaa ccattatcta ttttactatt atgaattatc atagtaatgc
   105841 ttttaaatat aatgaactgt atgttaacaa ataaattctt aagatatatt aacatataaa
   105901 gtcttaagtt tagttttatt taatcactat taagatatat taataggtaa agcttcaaat
   105961 ttagtttcat ttaaat
//
LOCUS       DAMJVG010000004        88577 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.004, whole genome shotgun sequence.
ACCESSION   DAMJVG010000004 DAMJVG010000000
VERSION     DAMJVG010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 88577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 88577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..88577
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.004"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            132..521
                     /locus_tag="PC512_000310"
     CDS             132..521
                     /locus_tag="PC512_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2440090.1"
                     /translation="MEQQDVIDKLRRGELMLMEYLWNKKSILSKKEIIEAMKKRYKWR
                     KSTTEILLKRLVKMKTLKKKRIGFQFSYEVLVTKKEYLNARKEERDISKYDNFFARIF
                     TTIHKRDKMTEEQLKAFIKNMEKIGKI"
     gene            614..994
                     /locus_tag="PC512_000311"
     CDS             614..994
                     /locus_tag="PC512_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2440091.1"
                     /translation="MGFKKLPDSELKVMKFIWGLEKKVASGEVVEAMKQTYGWNKNTT
                     LTILSKLAKKNYLYSQKTSKCTYYTIAVREKDYLKVETKKFFSFFHNNSLKSFFTALN
                     DEENLSDDKLDMLEEWVKNWEEDE"
     gene            1673..3103
                     /locus_tag="PC512_000312"
     CDS             1673..3103
                     /locus_tag="PC512_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDF2440092.1"
                     /translation="MILNQIFIEAGGIMRNKIIIGITFSLVLLMSGCASKQTAEINVL
                     ATTDLHGVIPYELTSYVKEERKKDKNLTLVDAGDFFDSGEVFGSSMDSYFSARYKDGD
                     NNTESYIETPISKDMKEVGYDVAVLGNHEFISNNKFYLDNMISDFEKQKINILSANTY
                     KKNGDSYTKPYIIKNINTPEGNVKLGILGLTIKEVGERKQWKDGKLVDSKSLELKDQE
                     GYNGELYMNDLVEDAKKWVGIMEKEKPDIIVAVAHTGEKPKKPKNPGNRIQDLAQQVD
                     GIDAIVAGHNHVQIEQHDYKNKSGENVIVTEPGKHGECISKINFKLEKNNDKWNIVDK
                     SSKLIKFEKNQESDKFGEFISSINKVSKDKKEIRLSEVKTPEWDKIYVFKSGTSADDI
                     YKTIGYKWRNISSPKGDDMVQIVVMNNNKPVSYVYGEAEVMPINIKCDESEYKDNVVT
                     IYPNKNDKFKIEKGKQEYSINLKHIQ"
     gene            complement(3251..3601)
                     /locus_tag="PC512_000313"
                     /pseudo
     CDS             complement(3251..3601)
                     /locus_tag="PC512_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904812.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
     gene            3596..4117
                     /locus_tag="PC512_000314"
     CDS             3596..4117
                     /locus_tag="PC512_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HDF2440093.1"
                     /translation="MFSIGGGYAIILLIQEKVVNQTGWISEKMFTDIITISQMTPGPL
                     AVNTSTFVGLQIGGFWGAVAATLGCVLCGVVISLFLYNFFQKHQNSTYIFEILNGLKS
                     ASLGLIISAAATIIILALFGTNKVYFNSIFEMLNWTALIIFFVTLLIVRKWKINPIVI
                     IIISGILGIFFYL"
     gene            complement(4246..5040)
                     /locus_tag="PC512_000315"
     CDS             complement(4246..5040)
                     /locus_tag="PC512_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2440094.1"
                     /translation="MIFCNSFITRKSSMNIVVTHTPIVTTLEMQKAYEPLAKHNVNIF
                     AFDFSGTGKSDGYEKDFSRNSIVKDLDSVITYIEKNYSSNIHLYGNTGIGGMFAQYYA
                     CSDNKLKSFAQFACVDYKNTTGVGYTYLTVKLLNFFFKFLPNFHITVKPPKYKGYNEV
                     YDNEFYKIFEKKNPHIWKNSTKIINTMLECFIAKDSKIKDGVNIPTLVFKTLHDRYFK
                     TQYFDSYYNSLKCKKKLVEINNVHNSYYIDSEKFCQEAYDWFVENQ"
     gene            complement(5264..8692)
                     /gene="uvrA"
                     /locus_tag="PC512_000316"
     CDS             complement(5264..8692)
                     /gene="uvrA"
                     /locus_tag="PC512_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HDF2440095.1"
                     /translation="MKINNYKNQSIITNPKKFENKYQDLPKTPIELLKVVQSLVIHGD
                     QGKLYGISFNKQQSDEELLRTIPQMLKRIFEINSNPLTIPRNPKQRLVGMCRDYSLLL
                     VSLLRYRGFEARMRAGFANYFESELTYEDHWLVEYYDTLTKRWIRIDAQIDDIQKNYF
                     QINFDTHDVGKTDGFLTGSEAWIRCRQGHAHQDDFGYNKNWKGWHSVKGNLLHDFNNM
                     IGLELLPWDLWTELSSKKYNQLTRAEKNLLDEMAEILSSGNIKIEDLNLLIEKLPEDY
                     LKSIFSQLKILGISEIKELGNPLELEKKFKFTKSINKSIKNSLCHNKSSIYLKGGRQN
                     NLKDVEVTIPKNQITVITGVSGSGKSSLAFDTIYEEGKRRYFENLSNGAKLSEQLQKP
                     EFDLLQGLTPTIAIEQKKGSQNPRSTVGTLTSIWDYLRMLFVSIGKSYCPYCKIPLEK
                     KNNTKNYCPHCQTIFSKINTSTFNANSHTGACHDCNGLGFTYQVNPQLIVKDPTISIL
                     DGATYYFGKLKGKKPNGNWMVGELYAIAKDKNIDLDIPWNELPRDFIDAILYGTDDKI
                     YEFSFESKGRESKIRRPASGAINHIQRLFRESSSENNTLHQYMNKIPCNTCGGELLCI
                     EARFTTIKGYRFPELTKMTIEQLWNWLCELPNQLQKNELSLVNDILTELKIRVSYLLK
                     VGLSYISTDRTAPTLSGGELQRVRLSSQLGSELVGLTYILDEPSIGLHPRDHNLIIKM
                     IEELRDKGNTVIVVEHDKDTILSADYIIDVGPSAGTKGGFIIAEGTTQEIIKNPNSIT
                     GKYLSTYNKISSQNKIIPSKWLSLKGCHANNLKNIDVEIPLNCMCSITGVSGSGKSSL
                     VFHSLLPALEEKLKQKSIPDKNYTEFTGFDAIDDFILMDQTPIGKSSRSTPATYINIF
                     DEIRSLFAETPQAKQKLLDESYFSFNSKKGQCPNCQGLGKTKIILQYMADQWVTCSEC
                     QGKRYQKEILSIQYKGKTIADILDMEVAEAKTFFSDCSDIYRKLSLLDEVGLGYLKLG
                     QNTLGLSGGESQRIKLAKELGTKTKKRMLYILDEPTTGLHFKDIENLLITFRKLVNEQ
                     HSLLIIEHNTEVIRASDWIIDIGPDSGINGGEIVASGTPDEIKINPNSITGHFI"
     gene            9011..11245
                     /locus_tag="PC512_000317"
     CDS             9011..11245
                     /locus_tag="PC512_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF2440096.1"
                     /translation="MKLSRYKKNSLVLSIILCSLIISILVITVFNTVKLHNISNKQSK
                     NYLNDVSTQIVMNVDSKIKFILSDLRIMADFIKQYEGDSRYEYLSKRKTSYKYYDVGI
                     IDLEGKAEFLSGKKFDLKNTVSYKKGIEGKEYSEVIESMGFVLYSVPIFNDNHEVSSI
                     LIGVSNKESMNEILNIDNFNGKGTIEIINSKGKPLFIGKNTELIKDLSHKYKSSGDEP
                     WAQKMLEDFKNDKSGNITITSSKGVQCLLTYHPITRGLNDWHFLLIVPEDAVLGELNK
                     LNSFTITMTFIITCIIGIITLILYIIRRKYVNQIENIAYLDSITNGINSTKFSMLVKP
                     LISESPDSTYMMIAMNIKDFKLINDCFGSEKGNMTLKHLYNILYKNIDENEEFVCRHD
                     ADLFYLLIKNRPVLEALELLYKIEADTNYFNKNRENPYFLRLSVGIYTIENHNEDLIT
                     IQDHANTARKSFNKTHQSDFSFYSDIERKRLISEKEISNLMEKALENKEFFMCLQPKI
                     DIKSGKISGAESLVRWKNSEKGIIYPSDFIPLFEKSGFICKLDLYILEETCKLISKWI
                     KEGKEVLRISVNVSRQHLNDKLFLEKYKHICNKYNVPTCLIDLELTESIFLENPEAID
                     IIEDIHSNGFKCSIDDFGFGYSSLGILKDFKVDIIKLDRSFFVSKNNIDRGKVVIKSI
                     IELSKRLGMKVTAEGIEELEQVEFLKNVGCDYIQGYVFSKPLLISDFENFAYENNKIK
                     NIHY"
     gene            11501..13531
                     /locus_tag="PC512_000318"
     CDS             11501..13531
                     /locus_tag="PC512_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2440097.1"
                     /translation="MISGRMLLIMNFLKGKNKTSYKDISKQLSIEERKVRYDINNLNI
                     VLRSLNKSVIQKMNKGVLIIPDDFQVVCINNNEYVFSLTERVSIMKIISMFKIDNLNL
                     EKLSKEFQVSRSSIKNDLNVLSSELERNQITITYDKSFKISGEEDIIYKQRLNILKSY
                     SYLFGKEKSDLSVFEKYLVNVIEKIFKGIYLIDIYNWSMNLLLQMGWTLNDESFTWYV
                     SNIFLFTWYIHSDEKHPLESASLSEPCFENKFDQEFETIIQKKLTKEQIFLLKSFVFF
                     TNKYASLNEDMDLISTEIIVQDLIYNMSEILEISFKEDMILYKGLLNHIAPLIERIKQ
                     NIQIYEELLHVIPDKYQYVLEATKVSIQKNRVLSQIKNENETILLAIHFLGSIHRNER
                     NNYKNILLVCGFGYGVIAMLKDSLVNDYQINIVESIPSYKLQDYKDWESIDFIITTSK
                     IVIDLPKTIIEINPFLQEEDYLKFEEKGIKRKNVLTNYMSIKKRLDFLEEDAQKRVLS
                     IICQELGYSDERILFRQLNLSDLIGIDTIRIIDGDMKWEDAVKFSSNILANCDFVSAQ
                     YAENIIDILKNVGFYAVKDNEFALLHGNDSSLVKVSSISLLICKEAVSFGDKKVKIIF
                     CLASRDKKEQIPAIINLTKMVYKTNFIAMLESAKTKEEAEVLIHKYEKEVTV"
     gene            13528..13980
                     /locus_tag="PC512_000319"
     CDS             13528..13980
                     /locus_tag="PC512_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2440098.1"
                     /translation="MNKLVNVKCSFKIHVNSKEEAIISLVDVVSKEGYLIDKNQFLKD
                     VLKREETLSTYIGHGIGLPHSQSVGVKNSCITIGKLDTPIEWTEEGEKVDLIFLISVT
                     KDNENNLHLKILSKLARLLMHESFRNQIRCSDEQTVYNLIKEKIEEED"
     gene            13982..15037
                     /locus_tag="PC512_000320"
     CDS             13982..15037
                     /locus_tag="PC512_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit EIIC"
                     /protein_id="HDF2440099.1"
                     /translation="MRILKFLQKHLMTATSYMIPFVVAGGILFALSVTLSGQAAVPET
                     GWLAKLNQIGAAGLALFIPILGGYIAFSMADKPGLAPGMIGAYLAKEVNAGFIGGIIA
                     GFIAGFVVLQLKKIKLAPTMRTLGSIFIYPLVGTLITGGIIVFLIGEPIASFMTWMTN
                     WLNGMSGVSKIPLGGILGGMIASDMGGPINKVAATFAQTQVDTLPYLMGGVGVAICIP
                     PIGLGLATLLFPKKFSKEERDSGKASLLMGCVGITEGAIPFATSDPVRVIPCIMAGSI
                     VGNIMAFLLGCLNHAPWGGLIVLPVVDNRLGYIASVLTGAVVVAVLMKLVKKDVKEDE
                     EIEEDLDESIELIFEEL"
     gene            15104..15412
                     /locus_tag="PC512_000321"
     CDS             15104..15412
                     /locus_tag="PC512_000321"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose-like transporter subunit IIB"
                     /protein_id="HDF2440100.1"
                     /translation="MKIVAVTSCPSGVAHTYMSAESLELSAKKFGIEIKVETQGSSGI
                     DNELSLKDIDEATCVILTNDVEIRNMERFKGKKVVRMSVSEIIKKSDALIKKIKDTFQ
                     "
     gene            15516..16781
                     /locus_tag="PC512_000322"
     CDS             15516..16781
                     /locus_tag="PC512_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II D-tagatose-bisphosphate aldolase,
                     non-catalytic subunit"
                     /protein_id="HDF2440101.1"
                     /translation="MKKLPIKTVVQRLLNLQEEGKSATLLGIGPMSPNLLQASFELAK
                     DDDFPLMFIASRNQVDADELGGGYVNGWNQETFTKDIKKVADKVGFDGLYYLCRDHGG
                     PWQRDKERNDHLPVDEAMELGKKSYLADIEAGFDLLMIDPTKDPFEIGKVIPLDVVLE
                     RTVELIEYCENERKRLNLPDIGYEVGTEETNGGLTSTETYETFITRLKVELDNRGLPM
                     PTFIVGQTGTLTRKTEQVGTFNFRNAYDLAQMAKKYGVGLKEHNGDYLDDVTLLEHIP
                     SQIIATNVAPQYGTEETRAYLKLAEVECKLEKEGLVEKTSNIRHVLLVNAIECGRWRK
                     WVVGEQKNLTTEEIFKDEVLSNEILDIAGHYTFNNDDVKKEIEVLYDNLSKNNIDGQR
                     FVVDHIKRPLRDYAECYNLKGVTTRILNK"
     gene            16869..17585
                     /locus_tag="PC512_000323"
     CDS             16869..17585
                     /locus_tag="PC512_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HDF2440102.1"
                     /translation="MINLIFDVDDTLYNQLTPFYTAYNKVFSSIKDISIEDLYMSSRK
                     YSDEVFHMTENGEMPIKEMHIYRIMKAFEELGNSITEKDAQSFQDEYIYQQSQITLIP
                     EVERILNFSKERNINLGIITNGPSNHQRMKLKQLNIENWVDKSNIFISSEVGFSKPDT
                     NIFRVAENVMNLDRENTYYVGDSYRNDVLGAKKAGWKSIWLNHRGHEVEELFYKPDFV
                     ILEHKDLISLFIKICSYKNM"
     gene            complement(17780..18073)
                     /locus_tag="PC512_000324"
     CDS             complement(17780..18073)
                     /locus_tag="PC512_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein"
                     /protein_id="HDF2440103.1"
                     /translation="MRNMIENLIKNNTYIDDKVIMLSMLSSAKASANMYLNSALTSST
                     PELRAIYSASLTQMVEGHTALTELSINKGWVKPYDKPIQQLTCSYKESQNVID"
     gene            complement(18079..18294)
                     /locus_tag="PC512_000325"
     CDS             complement(18079..18294)
                     /locus_tag="PC512_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440104.1"
                     /translation="MRILSETEKISLAAVIKMESDGLLMQRAINMLISDEDLKRQSES
                     SILATEGRIKAMQQFIVENEILISEEV"
     gene            18743..19141
                     /gene="tnpA"
                     /locus_tag="PC512_000326"
     CDS             18743..19141
                     /gene="tnpA"
                     /locus_tag="PC512_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011291581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HDF2440105.1"
                     /translation="MYKSNKNIVYDCKYHIVFCPKYRKPVLVGEVEKMLKEILPYKAD
                     ELGAEIIEMETDKEHVHLLISCDPQYGIHKVVKGLKGFSSRVLRENFPHLKSSMPSMW
                     TNSYFVGTVGSVSLEVVKQYIENQQVRTKK"
     gene            19138..20301
                     /locus_tag="PC512_000327"
     CDS             19138..20301
                     /locus_tag="PC512_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF2440106.1"
                     /translation="MIKTHRVKLNLTRTQFELVREKQMESANCWNYIVNLSKEYYFEH
                     KQWIKKNDIQKLIKGKYNLHSQTIQAISDKFDANRKTISELRKKGNTKAKYPYKTKKF
                     YIIPFKASAINRNAKGNLKLSMSKGRYLELDFNVENIKTAEIVWRNGYYLYYTFDNEL
                     NGVVAKGTNTVGVDLGEIHSIASVTNEGVGLILSNREGRSIKQFRNKMYAYISKRLSK
                     CKKGSRQSKKLWRLKNKIRSKTDNQLMNLYHQTTRKFIDFCVEQKVCEIVLGDIKGVE
                     KDTKKKKRLNRVNRQKISQMEYGRIKDYIKYKAKEQGIEVKLVKENYTSQTCPKCSKK
                     HKPTGRTYSCTCGYETHRDIVGAWNILNKKHKYGLVDFRINHKQPINLKVSTV"
     gene            complement(20685..21197)
                     /locus_tag="PC512_000328"
     CDS             complement(20685..21197)
                     /locus_tag="PC512_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF2440107.1"
                     /translation="MLEVIKNRRSIRTYIDKNIEEDKITEILKSAMQAPSSKNAQPWE
                     FIIVDDKELLKQLSKSQHRAKHIEFAPLCIVVLGNRDKFLKPGKWIQDLGACTQNLLL
                     EVTNQGLAACWAGVFPKNKVVNKVRQTLDLPLKLVPYALISIGYSEEKNEFIDRFDEN
                     KIHRNVYKNR"
     gene            21647..22123
                     /gene="purE"
                     /locus_tag="PC512_000329"
     CDS             21647..22123
                     /gene="purE"
                     /locus_tag="PC512_000329"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HDF2440108.1"
                     /translation="MKVAVVMGSKSDYPKLEEGIKLLEKYGIEVVARALSAHRTPEQL
                     SIFLKEIEDDTDVIIAAAGKAAHLPGVIASQTLIPVIGLPIKSSTMDGLDSLLSIVQM
                     PKGIPVATVTIDLGLNAALLALQIMTLKYPKLKEDLKSYREEMAQKVLEDDKNLRG"
     gene            22129..22827
                     /locus_tag="PC512_000330"
     CDS             22129..22827
                     /locus_tag="PC512_000330"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HDF2440109.1"
                     /translation="MLLYEGKAKQVYSTDNENEYVVYYKDDATAFNGEKKAEISSKGI
                     LNNKISTIIFEMLKENNINTHFIKSLSDREMLVKKVEILPLEVIVRNIAAGSICKRVG
                     LEEGVVFDEPIFEISYKNDAYGDPMLNDDYAVAMKLATREELKFLREETLKINELLKA
                     FFLKLNLKLVDFKIEFGKDSEGNIILADEVSPDTCRLWDVNTNEKLDKDRFRKDLGDL
                     VEGYTEVLSRMNNK"
     gene            22839..24206
                     /gene="purF"
                     /locus_tag="PC512_000331"
     CDS             22839..24206
                     /gene="purF"
                     /locus_tag="PC512_000331"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HDF2440110.1"
                     /translation="MCGVLGIYSNKDVTKELYYSLYSMQHRGQESCGLALLDDGEIKY
                     KKDMGLVGDVFKENELSKLKGNIGIGHVRYSTAGGSHVSNCQPLVGSCRKRQLAIAHN
                     GNLVNANYLKDMLEEDGYMFQTNSDTEVILYILARYYKGDIVESLKVTMDYIKGAYAL
                     VIMSQEELVAVRDPHGFRPLVLGKKGDEYIFASENCAIDILGGEVIRDVEPGEIIVVK
                     DGELKSYFYSENYKPVKKSCIFEHIYFARNDATIDNVNAYEFRIKCGERLAQNETVKA
                     DMVVPVPDSGWPGAIGYANASGLKISEGLVKNRYVGRTFIKPTQEEREIAVKIKLNPL
                     STIIKGKSIILVDDSIVRGTTSKQLVKSLREAGAKEIHLRITSPPVAYSCYYGIDTPN
                     RSKLIASSNNVEEMREYIGCDSLKFLDIEGMLDATEHKSTFCKACFDGEYPVKKIDKE
                     ELLSC"
     gene            24200..25276
                     /locus_tag="PC512_000332"
     CDS             24200..25276
                     /locus_tag="PC512_000332"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HDF2440111.1"
                     /translation="MLTYKESGVDIDEGNRAVDLIKGKIKGTYDGNVVGDLGNFSGLY
                     SLKDFVGMKEPVLLASTDGVGTKLKIAQMMDKHDTVGIDLVAMCVNDLICQGAKPLFF
                     LDYIALGKLVPEHIEKIVGGIADGCKMSGCALIGGETAEMPGMYGEDDYDLAGFSVGI
                     ADKEKIVSGNNVKSGDVLVGISSSGVHSNGFSFIRKIFLETYNYKMEQYVEELGMTVG
                     EALLTPTKIYVKLALDVLAKHDIKAIAHITGGGLIENITRVIPKGLGLDINKKSWEKP
                     PIFKMIEGFNAVDERELHKSFNMGIGLVLIVDKENADDVVNFINNRENDNAAYVDKKY
                     SELLEDKAYIIGEVVDSHEGVELC"
     gene            25270..25863
                     /locus_tag="PC512_000333"
     CDS             25270..25863
                     /locus_tag="PC512_000333"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HDF2440112.1"
                     /translation="MLNIGVLISGGGTNLQAVIDGTESGEIKGQVKVVISSKQGAYGL
                     ERAKNHNIKAICETDEDKIIEILKENKIDLVVLAGYLKIISPKLVNEFRNKMINIHPS
                     LIPSFCGAGFYGEKVHQGVIDYGAKVTGATVHFVDEGADTGPIIMQDVVKVNQDDDAK
                     TLAKRVLEVEHRILKESISLFCENKLKLQGRRVFINE"
     gene            25856..27388
                     /gene="purH"
                     /locus_tag="PC512_000334"
     CDS             25856..27388
                     /gene="purH"
                     /locus_tag="PC512_000334"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HDF2440113.1"
                     /translation="MSKRALISVTDKTGVVEFAKELNKLDYEIISTGNTFKTLKENGV
                     NVMQVEDVTNFPEILDGRVKTLNPYIHGGILYKRDKESHVETVNEHKIHSIDLVAVNL
                     YDFEGTLKAGKSHDEIIENIDIGGPSMIRSAAKNYKDVIVVVDIKDYDSIIEKLKTDT
                     MTLEDRKKLSYKAFSTTGRYDALISSYFAGEVGDTYPDILNLTFQKEQTLRYGENPHQ
                     NGFLYSQSNAKNPILNYEQLGGKELSFNNLNDLHGCLEVMREFKDSEEVVSVAIKHAN
                     SCGVGLGKDAFEAYTKCYEADKVSIFGGIVGITSTIDKATAEKLNEIFLEIVVAYDFE
                     PEALEILKQKKNLRILKLAKIENSLQPYEMKYLDGKLLIQDRNNILAEKSENVTKEKP
                     TDAQLKDMEFGMRVVKNMKSNAIAVVKNGQTLALGCGQTSRIWALKNALENNKDKDFT
                     GAVLASDAFFPFDDCVTLAHEYGISAVVQPGGSIKDKDSIEACDKYDMVMVFTGIRHF
                     KH"
     gene            27399..28649
                     /gene="purD"
                     /locus_tag="PC512_000335"
     CDS             27399..28649
                     /gene="purD"
                     /locus_tag="PC512_000335"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HDF2440114.1"
                     /translation="MKILVVGGGGREHAICWKLSKEKNVEKIYCAPGNAGIANVAECV
                     NIGDTNIEELLKFAKENEIGLTIVGPEVPLVMGIVDEFEKEGLRVFGPNKKCAQLEGS
                     KAFSKEFMIKHNIPTAKYKEYTNLEEAISEIDSFGYPVVIKADGLAAGKGVVIPENRE
                     DAIATLKEMMSDKKFGAAGDKIVIEEFLKGIETSILAFVDNDTIVPMASAKDHKKVNN
                     YEQGPNTGGMGTFSPSEIYTEELANKVKETVLEKTLEGFKKDGLNFKGILFVGLMITE
                     DGEKVLEYNVRFGDPETQSVLFRLETDLHEIMEAILDNKLKDIEINYSDDEAVCVMLT
                     SGGYPDSYEKGKIITGLENLDDDIVVFHSGTKMFDGNLVTNGGRVIGITAKSTRVKDA
                     AEKVYENIKKINFEGMHYRTDIGR"
     gene            28674..32480
                     /locus_tag="PC512_000336"
     CDS             28674..32480
                     /locus_tag="PC512_000336"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HDF2440115.1"
                     /translation="MLNTENKDSMVRRVLVEKREGFDLEAKALKKDLVESLHIDNIEN
                     LRILNRYDVEGISEEVYENAAKTIFSEPNLDVVYYEEIPKLNDERVFAIEFLPGQYDQ
                     RGDWAAQCVQIVNQGIRPAINTAKVYILSGKITDEEFSKIKDYCINPVDSREASLEKP
                     ETLKMETEIPTTVEVLDGFIDLDENGLRTFVSEKGLAMTLGDLQHVQKYFKDTEKRNP
                     TITEIKVLDTYWSDHCRHTTFMTEIENVKIEDGKFNDIVKEAYQMYLNSRDNVYVNRH
                     KDICLMDIATVAVKELKKNGKLNDLDESEEINACSINVDVEVDGKMEKYLVMFKNETH
                     NHPTEIEPFGGAATCLGGAIRDPLSGRSYVYQAMRVTGSADPRTTLEDTLPGKLMQRK
                     ITTEAAHGYSSYGNQIGLTTGQVAEVYDENFVAKRMEIGAVIAAAPKENVVRERPEAG
                     DVIVLLGGKTGRDGCGGATGSSKEHSEESILTCSAEVQKGDAPNERKIQRFFRNKEVA
                     QMIKRCNDFGAGGVCVAIGEIADSLDINLDLVPKKYDGLDGTELAISESQERMAVAIK
                     KENKDKFIQLAVEENLEATHVATVTDTGYLRMFWNGKAIVDINREFLDTNGVKQTTDV
                     HVTKVDEENTFFSSNEIVKDVKCASMKDKFTKVLSDLNVCSQKGLVEMFDNTIGGNTV
                     LMPFGGKYQATPTQGMVAKIPVLGGETNTSTIMTYGYNPKVGKWSPFHGALYAVVESV
                     CKLVAIGGNYSTTRLTFQEYFEKLGNNPEKWGKPFSALLGAFYAQSKFEIPAIGGKDS
                     MSGTFKDIEVPPTLVSFAVDTVDAKKVVSPEFKKADSKVVMLCVNKAENDVVDFEELK
                     RNLDKVRELIHGNKVLSTYALGFAGVGEAISKMAFGNKIGFKFSEEAEKAFTDNKLFE
                     ASYGNIVLELANDDLSMLEGYNYVVIGSTVKEASIFIKGEELALDELYKAHCSTLEPI
                     FPTKTEEVKSKIETISYISQGEAKKSSLSIATPRVFIPAFPGTNCEYDSARAFERAGA
                     NASIRVFKNLTYKDIEDSIDTIVNEIKSSQIIMLPGGFSAGDEPDGSGKFIATVFRNP
                     RVQEAINEFLTQKDGLMLGICNGFQVLIKLGLVPYGEIRVPSESAPTLTYNNIGRHQA
                     KIARTRISSNKSPWLAQTNVGDIHNIAISHGEGKFVASEDVMRELIANGQVATQYVDF
                     NNEATYDIEFNPNGSFYAVEGITSADGRVFGKMGHSERIGEEVYKNIIGEKDQKIFES
                     GVKYFR"
     gene            32686..33558
                     /gene="rfbD"
                     /locus_tag="PC512_000337"
     CDS             32686..33558
                     /gene="rfbD"
                     /locus_tag="PC512_000337"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HDF2440116.1"
                     /translation="MKILITGSNGQLGKELVNQLEAINQSINQPKYVILATTRSDLDI
                     SNQTNVDNFILHNKPDVVVNCAAYTKVDACEDNIEIAYKINALGVRNLAIASEKVNAK
                     LIHISTDYVFNGFSKYPYREDNKTEPNSVYGKSKLMGEKFVEQFSHKYFILRTAWLYG
                     NGNNFVKTMIKLSLENKEVNVVNDQFGTPTSTVDLAKIIIRIMETEHYGVYHATCEGE
                     CSWYDFAKKIFKLKNIDIKVNPIKSNEFKCKAPRPLYSVLDNFMLKLIGLNSFRKWEE
                     SIEEYLERYDINEK"
     gene            33667..34536
                     /gene="rfbA"
                     /locus_tag="PC512_000338"
     CDS             33667..34536
                     /gene="rfbA"
                     /locus_tag="PC512_000338"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HDF2440117.1"
                     /translation="MKGIILAGGSGTRLYPITKCISKQTLPIYDKPMIYYPMSVLMLA
                     GIQDILIISTPRDIKAFEELFGDGSSLGLNITYAIQEKANGIAEAFIIGEEFIGNDRV
                     SLVLGDNIFYGYGFSERLENAVKRKGATIFGYHVSNPNSFGVVEFDKDFNVLSIEEKP
                     TVPKSNYAIPGLYFYDNDVVEIAKLVEPSDRGELEITSINSEYLKRGKLKVELLGRGM
                     AWLDTGTHKGLLDASNYVEVVQTRQGLYIACLEEIAYTKGYISREQLMKLAKPLIKTE
                     YGQYLLKLASEDM"
     gene            34585..35142
                     /gene="rfbC"
                     /locus_tag="PC512_000339"
     CDS             34585..35142
                     /gene="rfbC"
                     /locus_tag="PC512_000339"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HDF2440118.1"
                     /translation="MGKINVIKTKIEGLYIVEPNVFYDERGYFMESYNKKDFIEQGLD
                     MCFIQDNESSSRKGVLRGMHFQVKYPQGKLVRVTEGEVFDVAVDLRKDSQTFGKWEGV
                     ILSDKNKKQFYIPEGFAHGFLVLSEKAVFSYKCTNYYYPEFENGFIWNDKQISIEWPL
                     KGIEEIFLSEKDKKQKSFKDICTRR"
     gene            35180..36163
                     /gene="rfbB"
                     /locus_tag="PC512_000340"
     CDS             35180..36163
                     /gene="rfbB"
                     /locus_tag="PC512_000340"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HDF2440119.1"
                     /translation="MKKILITGGAGFIGSNFIHYMLNKYVDYFIVNLDLLTYAGNLET
                     LIEIQDNSNYKFVKGDISNREQVYKLFEEERFDIVVNFAAESHVDRSVENPDLFIKTN
                     IIGTQVLLDASIKYGVKRYHQISTDEVYGDLPIDRKDLFFTEQSSINPSSPYSASKAS
                     ADLLVSSYYRTYGLLTTISRCSNNYGPYHFPEKLIPLMILNALENKQLPVYGNGENVR
                     DWLHVYDHCTAIDLIIHKGNIGEIYNIGGHNERSNLEVVKMILNLLGKSEELISYVND
                     RPGHDLRYAIDATKIENELGWKAKYDFDLGIKETVKWYIENESWWKAVLSV"
     gene            36193..36861
                     /locus_tag="PC512_000341"
     CDS             36193..36861
                     /locus_tag="PC512_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HDF2440120.1"
                     /translation="MNEISSLINILALTQLSGSNTTNQCNCTYNNSSGFDMIMMTLLK
                     ALSQNNQHTSNSYNLLSNSENLFNELDNVVNNTTSRFIDVDTKDKNVKLRIENAVDQA
                     SKKYNVDSNLIKAIIKVESDFNPNTVSSAGAKGLMQLMPENCRDLGVTDPFNIEQNID
                     AGTRHIKEYIDMFGGSIEMGLMAYNGGPGRMKSRGVESISDLYKMPKETQNYIPKVMK
                     YYRG"
     gene            36870..37298
                     /locus_tag="PC512_000342"
     CDS             36870..37298
                     /locus_tag="PC512_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaaR family protein"
                     /protein_id="HDF2440121.1"
                     /translation="MGINIDKLNISPSINMEVKKLKESNKFSDKLNSLKQSSSLEDIK
                     RNLESVKKAGERLVLTQNYGDISIYKNAVKEYLKSVVDNMYSLDKNSSFWEHQYYKNV
                     KIVDSKLEDMTSKLISEEKENIDIVSTVDMIQGLLIDMYR"
     gene            37322..37636
                     /locus_tag="PC512_000343"
     CDS             37322..37636
                     /locus_tag="PC512_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HDF2440122.1"
                     /translation="MNSKKEDIYELNFGQLIEEKSGVIEENQNVFNAKVNVAVSIGNT
                     TETIKNILDLKEGSIIKLSKNVDEKLDIYANDRLFAYGESIITNERLSVRLSKIEDPD
                     VN"
     gene            37788..38063
                     /gene="flgM"
                     /locus_tag="PC512_000344"
     CDS             37788..38063
                     /gene="flgM"
                     /locus_tag="PC512_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis anti-sigma factor FlgM"
                     /protein_id="HDF2440123.1"
                     /translation="MDIKNVSSNIVVNNYLKNTSGIKKVEEVKKINKTDKIELSKFAK
                     EMASVSNMSDENIRNKKVDEIKNALENGTYKIKPKEIAKKMIEDMRG"
     gene            38068..38484
                     /locus_tag="PC512_000345"
     CDS             38068..38484
                     /locus_tag="PC512_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FlgN"
                     /protein_id="HDF2440124.1"
                     /translation="MITDLKVIIYEEKNIISKMMELLKEQFDYIVEKDLENLNMLNPK
                     LEDISRELASIEIKRRQLFGDDISMSEVVENSNDGYLKEIYTDLKHILALAKNQQESN
                     DSLIKKELIFTKKMINFIKPADKQTTTYNSYGNIRK"
     gene            38502..39812
                     /gene="flgK"
                     /locus_tag="PC512_000346"
     CDS             38502..39812
                     /gene="flgK"
                     /locus_tag="PC512_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgK"
                     /protein_id="HDF2440125.1"
                     /translation="MAGLFSILNTANSGMNAHQKAIQTISHNISNLDTDGYSRQRTEF
                     ATNSPMYMPSLSNSIARGQLGTGVHVTDVTRARNSFYDYQFRAEAHKYGKTVSKYDYY
                     NTIETILNEPSDYGISAGIDDFFKGWESLSKDINSDSKKSLVVENASNLATLISESYK
                     KLDKLKEDIDSNIDTEIKQINDMLKSLEDLNKSIDIISGSGSTPNDLLDERDRILDNL
                     SFKLDFENSDVKNMLADGKLELNELKNPDGTWKTGISGTLQGLFEMHGKIDTYKSDLK
                     DVSDGLAKQINDVYNTSAGITVTDFFITSNVDGEDIIKINPAIKSNPNELKLTADEAS
                     KIAKLKDEKIDIGVAGGKVSTISDHYKAFAESIGLDSQKVNQDEANQRKIINNIDNSR
                     MSVSGVSLDEEMTELIKIQRSYQASAKVMSTAVQLLDVVINGII"
     gene            39831..40763
                     /gene="flgL"
                     /locus_tag="PC512_000347"
     CDS             39831..40763
                     /gene="flgL"
                     /locus_tag="PC512_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgL"
                     /protein_id="HDF2440126.1"
                     /translation="MRVSTGMMSSSYLNSLQDNLQRLDKVNRQVNTTKEINKLSDNPY
                     KAIKILNSKSEIKTMETYVENCKDTGNWLETTDTALDQLGKLLSDIKKTLVASGDGAY
                     SDDELKTLSNETNEKMKEIANALNATHEGKYIFSGSNTGVPPVECIDNADGSVSLKFN
                     SSLNLNKLNDSLSMDIAQGISVDYNVKLSSLGFDPTKTDPFEELNNISKKLANPDADA
                     IKELTTTCLGDMEQLIENTVNVRSIYGTKANTVEAMKEKNDDSLIQLKDILSQNEEID
                     YGEKLVQLKAAELTYQASLQTGGKLFNVSILDYI"
     gene            40779..41171
                     /locus_tag="PC512_000348"
     CDS             40779..41171
                     /locus_tag="PC512_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein FliW"
                     /protein_id="HDF2440127.1"
                     /translation="MMKVTLKKGILGFENLKEYELLDIEDNDYLKEFNSTEEEGIGFV
                     VVSPFEIINEYEIVLNQETIEKLEVKSPKDVVLFNIITLGQTFEESTVNMKAPIVINI
                     KTNFGMQIILQDDKYSIRHPLLRGDSGC"
     gene            41165..41377
                     /gene="csrA"
                     /locus_tag="PC512_000349"
     CDS             41165..41377
                     /gene="csrA"
                     /locus_tag="PC512_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011987028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon storage regulator CsrA"
                     /protein_id="HDF2440128.1"
                     /translation="MLVISRKKDEAVLIGESIEVKIVGVDGNNVKLAISAPNNISILR
                     KEIYEKVKSENIKATNKNIKILKSLK"
     gene            41399..41794
                     /gene="fliS"
                     /locus_tag="PC512_000350"
     CDS             41399..41794
                     /gene="fliS"
                     /locus_tag="PC512_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HDF2440129.1"
                     /translation="MYGENPYNSYKQNAVFMASKEQLLLMLVDGAVKYTKIAKTAILD
                     KNTQKAHRELIRVQDIFTELMVTLDQNAGQWAKDMYRVYDFVRYELSRANIRKDIQII
                     DNVLPVIEQIKDTWHEADKKSKEERSRYK"
     gene            41794..42150
                     /gene="fliS"
                     /locus_tag="PC512_000351"
     CDS             41794..42150
                     /gene="fliS"
                     /locus_tag="PC512_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HDF2440130.1"
                     /translation="MELNLAELDKLSKEELLLMLVDGTVKYTNISKEALLNNDYLKAH
                     NELVRVQNIFTELMTTLDQDAGQWAKDMYKVYEFIKSELAIADENKDIKIIDDILPIV
                     KQIRDTWHEVYNQLKI"
     gene            42171..43694
                     /gene="fliD"
                     /locus_tag="PC512_000352"
     CDS             42171..43694
                     /gene="fliD"
                     /locus_tag="PC512_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar filament capping protein FliD"
                     /protein_id="HDF2440131.1"
                     /translation="MSSISPIRVTGLSGNFDMEGIIEASMIRDKEKVDKAKQEQQIVK
                     WKQEIYRNVIQESKDLYDKYLSVNSPNSIVSEKAYSSTRITSSDESIIVAKGSAGAEK
                     INYQFAVSQMAEPAKFTIKLNSSEPIVQQFPPNASGASSLTIGDVNIPISEQDTTSTI
                     VSKINSLCADNDIKASYSEMTGELIISRKQTGSSSDINLRVIGNDNLAQQIANDNGIT
                     FINDAGGNKVANVYGKNLEADVTDEHGRVTHISKEQNSFNIDNIDYNVNSKGTAKLTS
                     VTDTEEAVKNMQAFVDDYNKLMDKVYGLVTTKKPKDYPPLTDAQKEDMTTEEIEKWEK
                     KAKEGILRNDDELRGFVEDIQSAFFGDGKNIIALRKLGINESENYNKKGQISFNADTF
                     SKALIDDSDKVYKTLAGYSSNYDDKGMFEKLKDIVYEYSGSSTSKLPKKAGIEKTASA
                     SENVYSKQIAEQERNISRLVEKMNDKEKRLYAKYSALESLLNQYSSQMNYFSQAQGN"
     gene            43697..44032
                     /gene="fliT"
                     /locus_tag="PC512_000353"
     CDS             43697..44032
                     /gene="fliT"
                     /locus_tag="PC512_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FliT"
                     /protein_id="HDF2440132.1"
                     /translation="MDKLKEKLNLYKDISLQIINLIEKEEYIKISIKLGERQEIINSV
                     SEIDRNDFIQLYNRMELIEIDSRIRDILQGQLLEVKKELHEYKLTKQVNTMYYNLNRE
                     KVNIFNKKV"
     gene            44134..45006
                     /locus_tag="PC512_000354"
     CDS             44134..45006
                     /locus_tag="PC512_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellin"
                     /protein_id="HDF2440133.1"
                     /translation="MRVNTNVSALIANNQMGRNVNAQSKSMEKLSSGVRIKRAADDAA
                     GLAISEKMRAQIKGLDQAGRNVQDGISVVQTAEGALEETGNILQRMRTLSVQSSNETN
                     TAEERQKIADELLQLKDEVERISSSIEFNGKKLLDGSSTEIRLQVGANFGTNVAGTSN
                     NNNEIKVALVNTSSIMSKAGITSSTIASLNADGTSGTNAAKQMVSSLDVALKELNTSR
                     AKLGAQQNRLESTQNNLNNTIENVTAAESRIRDTDVASEMVNLSKMNILVQASQSMLA
                     QANQQPQGVLQLLG"
     gene            45099..47240
                     /locus_tag="PC512_000355"
     CDS             45099..47240
                     /locus_tag="PC512_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDF2440134.1"
                     /translation="MLLSIVMIVKNEEKILEKTLKSLTTLRNSIESELIIVDTGSTDD
                     TIKISKKYTEKVYFHNWNNDFSSMRNISISYAKGEWLLILDADEILIDSSTIVKFFKD
                     GLDKKFNSASIQLKNLYSYDKKLYGYCSVLRLFKNVDFRYHGKVHEQPIYKNPIFNNV
                     ADFEHYGYLFEDEEIRLNKVKRNEKLLFQELKENDNSPYTNYQLGKNFIILGKYQEAL
                     YYLEKSYELYSKLELAPGYLITSLVKTYLYLGKHKKCERLCLKYIKKDMNNIDIYYYI
                     AQAQVDLGKYENSIDSYKRYIYLLDNYEISTQANSLFSDTDTVGLRDEAIITLIKIYY
                     KLEKYEFVISEYNNIEDVEKKKNVYFSLFMSLYKLNRFEDIKNYYKEVSNSKIEKNSF
                     YRNIEEVINNIKEDEKEYVYKILCDIEGNYGILNQIRINKCVSIDKCKEILNEEKEII
                     YAYIIKIAFEEKIDLLDIFYEMEYVWIEKYLKYLLALERSFNLVLYKYIISRPNTSDM
                     EKIRVYKAISKVVLESISLSDEKYKEIFYLYIMYSYKYIRYIYSNLSDFELIKFVCND
                     LDKFTIEFKHLLDIKNKVNNANEKLEYIHSMRKLLNEYPFYNKIIKILIGELEENIKE
                     SEEFKDLKDSFIISIENMIETGKINDAKLLVDDYSKTFVDDIKILNIKGILYMFENKL
                     DKADFMLKKALSLDVENEDTIYNIEYLKSLR"
     gene            47264..49141
                     /locus_tag="PC512_000356"
     CDS             47264..49141
                     /locus_tag="PC512_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDF2440135.1"
                     /translation="MNIPIVVNEKSKDIIKDWQYTCTNEDIKFTSIIILTYNQIEYTK
                     LCIESIRKFTPKNKYEIIIIDNNSSDGTVEWLKGQSDIKSVYNNKNLGFPKGCNQGIE
                     LATGENILLLNNDVIVTPNWLYNLNKALWSQDNIGAVGPITNACSYYQQIDVDYKSIE
                     DMFIFAHKINKSNINLWKYRLKLVGFCMLIKKTVLDNVGVLDELFTPGNFEDDDLSFR
                     MIESGYKLLLCQDTFIHHFGSVSFKENRNKYTDIMYINRRKFETKWGFNPEYSGMIRT
                     DLISKIDDSLEANINVLEIGCGIGATLLEIKNIYKNASIYGIEISESAGKLAKYSADV
                     LIANIEKVKLDYKKDFFDYIILGDVLEHLIDPWKIVNELKQYLKKDGYLVSSIPNIMH
                     VSVLRNLVLGNFTYEDSGILDKTHLRFFTLNEITKMFNDSNYIINSITATSMPLSEID
                     NSFIDTICKESCKEMRQQYESYQYIVKASKILDTKRYSSISMINLKYALMRIDNELDV
                     DSNLSYIFDNYNITEPCFVDDIEYLIDTFVINKATLLNRLGVEAFNRGLGDFSINMFM
                     TVLEMDRDDIDSIYNITSVLCELEEFDTAYNLIKNSSEKVQSESDIQEILCFIEGKKY
                     E"
     gene            49134..51248
                     /locus_tag="PC512_000357"
     CDS             49134..51248
                     /locus_tag="PC512_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HDF2440136.1"
                     /translation="MNNDKICFITCVNDERLYEECLVYINSLDIPKNFSIETVALRGA
                     DSIASAYNKAMRETDSKYKVYLHQDTFIINKNFIHDILEIFKKNTDVGMIGVAGVKDM
                     PVNGIWWDSDKKAGKVYDSHTGKMDIYEFSNFEECFNEVMAIDGLIMITQYDVFWRED
                     KFDGWHFYDLSQSMEFRQNKYKVIVPKQNKPWCMHDSGVVNINNGYDEYRIKFVKEYI
                     NLDLYRENFYEFDKKKASTILKSNKHVMDCMKEELTEQLRLKNYKDVLGIVSKIAHFS
                     VFNHTGLYSCEECERALLECANNLPEIENTKLFTKKDLKRRKVLHVLSEGYSTGGHTR
                     LVKNWIEIDKDSVHSVVTTWQSDTLPDWLLKAINDSGGEVISLDLISDDYLKRAVALR
                     KIAYDWADIVILYVHMWDTIPVVAFGVDGKIPILHVNHYDSTFWLGTSIADIVIDFSE
                     TSQLITLDKRGIDKSEILPMPLKEKEVFSKSEVRKRYNLEDDVTIILTIASERKYNSV
                     NDINYFKIAKTLIENTDNTIIIVVGVDTENLYWKTLSNVTDNRVICFGTTANIDDFYK
                     ISDIYLESFMVGSHTSKLDAILYDLIPVKFKNEVSPIFTNMWNFIDKFDYKNIKEVID
                     MIRRYNTSEFDRDKIKAKQSEIKHFVIDKHCIEIKNYIDKIYNEVNHHKVKYDLYKND
                     EIEDYQLFVALYGYMVKNKNMS"
     gene            51257..52252
                     /locus_tag="PC512_000358"
     CDS             51257..52252
                     /locus_tag="PC512_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation glycyltransferase
                     FemA/FemB family protein"
                     /protein_id="HDF2440137.1"
                     /translation="MNNIHINKFEKSCEKNWDYFVENKSINGTFLQTRNFLNYHEEGK
                     FTDHSLIICKGEEILAVVPACETYEDGERIFFSHLGSTFGGIIIRSGFNDIRHVNAIT
                     NKLEIYLQEQNFDKVYLKNTSRIFCKEDTSLLEYFLFKNNYMFYDELSMFLELSKYKE
                     DILANFKYSKRRDFKYSLKNNLTFKRLYSDEDIVCFFNLLSNCLDSKGAKVIHSVEEL
                     LEFKNNRLKDIVEFYAVYIDDIMICGSMVFNFQERVYHTQYLASNSTYNKYYPMIFLY
                     YNLIKDALERNFKYLSFGISTLNRGKYLDEGLATFKEGFGSSAICNRTYYKNINK"
     gene            52344..53576
                     /locus_tag="PC512_000359"
     CDS             52344..53576
                     /locus_tag="PC512_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HDF2440138.1"
                     /translation="MKRLMILGSIKYFENIVMSAKREGIYTIVCDNRIDTPAKKICDE
                     AIDVDVFDFDKIKNIAIDKKIDGILTGFTDSLMKPYVYIANELNLPCVISCNQLESVT
                     NKAVMKNYFKNNGIPTTDYCIIESLKDLEKIQGLNFPLVIKPVDGYGSRGVYFVSNIE
                     ELIEKFEYSKEASQDGQVIIEEFYESEEIQGLAWVHNGESHVFYIGDRELVNIHTGRA
                     GKPDRLIYPSKYCFQYEEEIKSIYQNITQAFGIKNGPLYVQMLVGAYGIKVSEVMPRL
                     PGGCDYMAISQITDLDIGSLFANFSVNNEVNFDEIKKYNMHLSKCVYALPIYIRPGTI
                     KKINNIDKIENLDYVTQFLLLVKEGDTIGLYEDERQDCGRVYGVANNVFDANIKKKCI
                     HEMIEILDENNENMIENF"
     gene            53596..54540
                     /locus_tag="PC512_000360"
     CDS             53596..54540
                     /locus_tag="PC512_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase"
                     /protein_id="HDF2440139.1"
                     /translation="MKLITHEQIMSLNISQKQGYEWIKESFLTKKDCQLPPKISMVEE
                     GHVFYNVMPSLNHNHKIGGIKMVTRLPGRNPSLNSEIFLYNMEDAKLKAILDGNYITA
                     FRTAAVAALAIDTFAKKDFNTIAIMGLGVTASAIMNMLSYTLKDKNINIKLLKYKDQA
                     ESFVKKYEKNEQFSFEICDTHEELIVDSDVVISTVTYTDEYLSEFKWFKKGALLLPVH
                     VMGFGNVDYLFDKVYLDDYNHLKHLENIDRYKYSCEFYDVLSKQAKGRENDDERIISY
                     NIGLSIHDILFANKIYELCETLSCEEIELKEPKEKYWI"
     gene            54634..55041
                     /locus_tag="PC512_000361"
     CDS             54634..55041
                     /locus_tag="PC512_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxcM-like domain-containing protein"
                     /protein_id="HDF2440140.1"
                     /translation="MDKYNLIRFVSIGNEYIGNLVALESNKAIPFDIKRVYYIYDVPN
                     NVKRGFHAHKNLEQVLVCLNGSVKIKCYDGVKETIFNLHKNDVGLYIGTGVWHEMFDF
                     DEKTVLISIASEHYNEEDYIRDYKEFLKYLNNV"
     gene            55128..56219
                     /locus_tag="PC512_000362"
     CDS             55128..56219
                     /locus_tag="PC512_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HDF2440141.1"
                     /translation="MLVKFNNLLKQFQTHKEEYEQKIKDVMESGYYILGNEVKHFEEE
                     FANYVGSKYCVGLASGLDALIIAFRALGISKGDEVIVQSNTYIASVMGISINGATPVF
                     VEPNEYYNIDSSKIEEKINSKTKAILVVHLYGQASNMKDIQELCDKYNLYLIEDCAQS
                     HGAKYDGKMTGTFGDIGCFSFYPSKNLGAFGDAGAIVTSNEEIADKVKILRNYGSEKR
                     YYNKFVGYNSRLDEIQAGLLRVKLKYLNEIEIEKSKIVDRYLNEINNPKVILPKIENN
                     CTHVWHLFVLQVEKRDTFMEYLKKSGIESIIHYPIPPHLSEAYAYLGYKKGSFNIAEN
                     YSDKVVSIPLFIGMEDEEVSYIIKIINEY"
     regulatory      56528..56618
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            57027..57344
                     /gene="flgB"
                     /locus_tag="PC512_000363"
     CDS             57027..57344
                     /gene="flgB"
                     /locus_tag="PC512_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgB"
                     /protein_id="HDF2440142.1"
                     /translation="MNTYDIIKMGLDATNLRSQTIANNIANINTEGYKRHYITFEETL
                     NDAMPKIEEKTDNSKGLRVDGNNVDIEEEKVNQAMATLQYNALISFANGKIAMTKSII
                     SGR"
     gene            57352..57756
                     /gene="flgC"
                     /locus_tag="PC512_000364"
     CDS             57352..57756
                     /gene="flgC"
                     /locus_tag="PC512_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgC"
                     /protein_id="HDF2440143.1"
                     /translation="MSVFSGMRISASGLTAESLKMDIISSNVANINATRGPNGEAYRR
                     KVVSFEENYDNKLGMLGVKVTSVEDDKSPLKEVYDPSHPDAKPNGYVEYPNVNILVEM
                     TDLITASRAYDSNVDTLNAQKSMISKALEIGK"
     gene            57766..58083
                     /gene="fliE"
                     /locus_tag="PC512_000365"
     CDS             57766..58083
                     /gene="fliE"
                     /locus_tag="PC512_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein FliE"
                     /protein_id="HDF2440144.1"
                     /translation="MPITQINNLMQGAKLDNLIGEAKPLTLNNKEEKKNFEDVIIDTI
                     DKVNFQQVTADDMKEKFIKGEDVSMHEVMLIGQEAQLSMQYLIEVRNKIHDAYQEMNK
                     VQI"
     gene            58108..59658
                     /gene="fliF"
                     /locus_tag="PC512_000366"
     CDS             58108..59658
                     /gene="fliF"
                     /locus_tag="PC512_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar M-ring protein FliF"
                     /protein_id="HDF2440145.1"
                     /translation="MITSFKNKIKEQVAKSRTKISSLKKGTKIALGIGVIAICLALVF
                     TAISASKNKYAVLFSELDAQDAADISAELESKKIDTKVKGSTIYVPRTEVDKLRLELA
                     PSLTGGSKGFALMDDSSSIGLTDEEFQIKKQRMIQGEIEKTIKSFPQVEDTRVHITFG
                     ESSVFEKEAVPGSAAVYLMLKPGTTLEKNQIKSVMALISGSVTNIPEKNVQVIDNKMN
                     LLSEGILEDENVDENNQPINSGISVDKNKASEQALNKQLEKSILEMLEPIFGKGKVKA
                     TVNADLSFDTAEKTEIKIDPDKVAIKETRSKNSSKSAANNVQGVDANMNNQGNNNGTN
                     TEDSLDESFEYETGKIETHTIVAPGELNRLTASVAIDGKIAKGVQADVEDIVNNAIGM
                     DGARGDTLSVVSMVFDPEGKKEAKQELEEIKKEGFKKNIIKAVIGVVAVIAVGAIGYL
                     IYKKRSEREDMDYEDEDYISKSDSVDRKDNPLLGDDPELTLEEAVKMYAEEKPDQVTE
                     IIKTWLNE"
     gene            59671..60741
                     /gene="fliG"
                     /locus_tag="PC512_000367"
     CDS             59671..60741
                     /gene="fliG"
                     /locus_tag="PC512_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliG"
                     /protein_id="HDF2440146.1"
                     /translation="MSTEITNVNAFDLSDINESDKNEKVEGEGLKKAAVLLMTLGPNV
                     SSDIIKSLPDKQVQKIGLEIANISSIASKERREILKEFVEINRAKDYVIEGGLEYARE
                     LLSNALGNVKANKLLEGISINTSTKPFKHIIKLDVKKILEILRNESAQTIAVLLAHME
                     PENGAEVLSYLDFDLQNEVAMRISSMGSISPEVIKVIESSLEDKLHSISGDDFNDYGG
                     VSTLVQILINSDRKTEKNILGTIEEQNPDLAAQIKSHIFVFEDIVKLDDISIQKVLKE
                     VTMKDLVYALKGVDDEISDAIYRNQSSRAADALKEEMEMVGVIKVTQVEASQQKIANI
                     VRKLEREGAITIVRNFGGDFVE"
     gene            60734..61465
                     /locus_tag="PC512_000368"
     CDS             60734..61465
                     /locus_tag="PC512_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein FliH"
                     /protein_id="HDF2440147.1"
                     /translation="MNNKIIKSKKALYKGVLDLTIIDKVRVGESNVNKENDCRFRDEV
                     IKEAIESAEIKKNEILEEAKINAQNIEKQAYEKGYSQGQKNGYEDGYKESYDEYTQKA
                     KDEADFIKNQANLILLQANEKMTEYIKEKNKEIVRLAINMASSVLKKHFEDEESMSDL
                     LKQIIQDYEGSSSFIVRCNSFYKDNIEKEFELFKEETSLKSSVFVIADDSIDKGNAII
                     QKENGRIIVGIDCAMEKLKEELLGE"
     gene            61469..62788
                     /gene="fliI"
                     /locus_tag="PC512_000369"
     CDS             61469..62788
                     /gene="fliI"
                     /locus_tag="PC512_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein export ATPase FliI"
                     /protein_id="HDF2440148.1"
                     /translation="MYKTDISIDFDKINKKIENLELTISEGRVKKIIGLTVEVEGIKA
                     FVGELCVIYNQVNKPVNCEVVGFKDKEVILMALGELTLIAPGCKVISKGIPLSVMCSD
                     NLLGKVLDGLGNPIDNSDAVLGDRYNLNNEPPDPMKRKKIRNIMETGVRAIDAFTTCG
                     EGQRIGIFAGSGVGKSTTLGMIARNAKADVNVIALIGERGREVLDFIDKDLGEEGMKK
                     SVVVCATSDKAPLVRLKGALTATAIAEYFRDQGKKVILMMDSVTRFAMAQREVGVAIG
                     EPPAQKGYTPSVFAMLPKLMERTGTSDKGSITAFYTVLVDGDDFNEPIADTTRGILDG
                     HIVLSRDLANKNHYPSIDVLNSLSRLMNEIASKEDIKIASFARDMLAEYREAEDLINI
                     GAYASGTNKKIDEAIYYHEHIINFLKQGINEKSSFNETISSLRRVFE"
     gene            62819..63265
                     /gene="fliJ"
                     /locus_tag="PC512_000370"
     CDS             62819..63265
                     /gene="fliJ"
                     /locus_tag="PC512_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012815984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export protein FliJ"
                     /protein_id="HDF2440149.1"
                     /translation="MELDKNFKFRLQKVLDLKVKDEEEIKMEFAKIQQKKIDIETNLE
                     NLESNYSKYSISKNNDSIQNQKITINYLLALNNSIMDLSEELDKSTNELEKARKQLIS
                     KQIERKSLEKLKEKKYGQYYKEENLKEQNTNDEFASMSYLRNRQVL"
     gene            63294..64499
                     /locus_tag="PC512_000371"
     CDS             63294..64499
                     /locus_tag="PC512_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-length control protein FliK"
                     /protein_id="HDF2440150.1"
                     /translation="MKIQADSYNIIKDIGDRKSSSKNKNIKNNKFEDNLYKATDHKKV
                     KDRREVSKQNISSDKPENSDNECHLDEDKSNHLEDENTYEKDCSKNNEALQQLLNLLK
                     DNYKKDKDINTILNNIEKLSISDELKQELKLNKNILNKIANQNSELNKANINNSNDIE
                     NLDIVKLRELLEDNANKDIEVITKTTENDTKNIDLYSFDSNRMDNLNSNKQKDDSSDI
                     LEKLAGVNGNKSGNFGQVINKNVDMNKIKNDNVNLKQIESNVMDDSIKAIKHMKTNDI
                     QELTIKLRPKELGDMNIQLLKDGESMRAVVTVFNKDVFDSINKNIADLKQHLELTNVN
                     IKDVSVQMHSDNTNTSDTFDKAFEQQNRQNNQENMSKKNTNDKHNNVVIEDDIKENTI
                     DDDRVDLLA"
     gene            64517..65125
                     /locus_tag="PC512_000372"
     CDS             64517..65125
                     /locus_tag="PC512_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlgD"
                     /protein_id="HDF2440151.1"
                     /translation="MYGIATALAGTQGNYRSNNLSQLERNINDIANKQVRSKGNQTVT
                     DNGTPIIGQGDDADKDLFMKILVAQMGNQDPMNPQDPTEYVSQLAQFATLEKMSAMNE
                     KLDVLLALSNSTLINSALSMATSLIGKEVEVSGEEKEDENIVGVVKSTYIKDGEVHLE
                     LEVDGSDKTVGVKYEKLLKIGEVDENSGEENDSSEHESPEEA"
     gene            65152..66135
                     /locus_tag="PC512_000373"
     CDS             65152..66135
                     /locus_tag="PC512_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein"
                     /protein_id="HDF2440152.1"
                     /translation="MIKAMYSGVSGMKANQTKLDVIGNNVANAGTTSFKKSSARITDS
                     FYQTVLYASAPTAALGGTNLGQVGVGSKISSINKDMVQGNVQPTNRPSDLMIDGDGYL
                     PVVRQGTVMYTRDGSFNLDTGFKAADGALKNIKGGRLVNGDGYMLQGMIYDGEYKADT
                     GEFVKKGDAKGKEPIVIPLQSISPKDGTVQNVLEYNISKDGTVEFLLSDGQRTQFVYD
                     IPDGAKVGDTPAGIDKLKGTIQKVQTYAFQNPAGLDAEGGNLFKPSANSGDPQIAGAT
                     GTIIQGAIEASNVDIAEEFTEMIIASRSFQANSKIISTSDEILQEIINLKR"
     gene            66148..66351
                     /locus_tag="PC512_000374"
     CDS             66148..66351
                     /locus_tag="PC512_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar FlbD family protein"
                     /protein_id="HDF2440153.1"
                     /translation="MIRVTDLNGRKYILNSDLIVRIDSVPESRILLTTGEKNLVKESV
                     DEIVDKVIKYKRKINVGYIRSEK"
     gene            66351..67169
                     /locus_tag="PC512_000375"
     CDS             66351..67169
                     /locus_tag="PC512_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MotA/TolQ/ExbB proton channel family protein"
                     /protein_id="HDF2440154.1"
                     /translation="MKKTDSLTFIGLIVSTVLVLVGAAKGSSSGLKNFFDVSSILITV
                     LGSFGALMITFTIDDIKLIKNALQYSFKTMSVSKLDLLEQFKTLSKKARKEGLLSIES
                     DVMGIEDPFMKKGLELCIDGLEINEIRSILELEIDSVEDTNNRYSKLFKTWGTFAPAF
                     GMLGTLIGLIQMLADLTSPDLIASGMGKALITTFYGSLLANIALNPIAYNIDEKTEKE
                     IYVKEMMLEGIISIQSGESSIVVEERLATYLSNNEKLEIMKSNKNTERAMSNGA"
     gene            67159..67854
                     /locus_tag="PC512_000376"
     CDS             67159..67854
                     /locus_tag="PC512_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HDF2440155.1"
                     /translation="MARKKNKKKDEINPDAWLATYADTITLILTFFVLLYATSVVDME
                     KFKNIADALKGQFSGTSIFSTGSSTSEKSPIDSVLVDKNDKSNLEQDLKDKVNNSNLQ
                     NSVTVKDDSRGILLELDDSILFDSGISELKVDSKATLNKVYDMIKMMKNKIVIEGHTD
                     NVPVKSSTHESNWDLSSSRAVSVVRYFVEEKGMDPRLFSATGCGEYQPLVSNETAKGR
                     AENRRVNILITID"
     gene            67866..68309
                     /locus_tag="PC512_000377"
     CDS             67866..68309
                     /locus_tag="PC512_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body-associated FliL family
                     protein"
                     /protein_id="HDF2440156.1"
                     /translation="MFKNKKIIIIILILIIFSAGAGFFILGEGGNKQVDKIADLFIPT
                     GKGKDEVKTENLDLEEMVLKLADEGVRYLKVSITVSYDSSYKDIEKNTPLIRDNIINC
                     FMAKRADDFTADNLKNIKEEIKNTLNIQLGENVIQNIYFTNIVVQ"
     gene            68324..68698
                     /locus_tag="PC512_000378"
     CDS             68324..68698
                     /locus_tag="PC512_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliZ"
                     /protein_id="HDF2440157.1"
                     /translation="MILYLLKILICIPIILILIVLSLKISQGTLLKKYNDKYVKILDI
                     VNISKNNSIIILKIGEEGCIMASSSSSMSKIKDLTKEEILKIENDIKERNFKIQDFKM
                     ERIKKKYDFSRYIGKFTKKEDK"
     gene            68699..69364
                     /gene="fliP"
                     /locus_tag="PC512_000379"
     CDS             68699..69364
                     /gene="fliP"
                     /locus_tag="PC512_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425215.1"
                     /note="The bacterial flagellar biogenesis protein FliP
                     forms a type III secretion system (T3SS)-type pore
                     required for flagellar assembly; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system pore protein
                     FliP"
                     /protein_id="HDF2440158.1"
                     /translation="MELLSKLPLADVPYTSSMQLFLFLTALMFLPFVMFMMTSFVRIV
                     ISLSFLKSALGAQQAIPSQILVGLAIVLTIFIMRPVLNEINEKALQPYMKEEVTMEEA
                     MKEAEGPIKEFLLTQTRQTDLDLFVEQAGLKEKKLTRENIPLSVVVPAFAISELKTAF
                     QIGFLIYIPFLIIDLVVASVLMSMGMFMLPPVMISLPFKLLLFVMVDGWNLIVKTLIL
                     GFG"
     gene            69377..69646
                     /gene="fliQ"
                     /locus_tag="PC512_000380"
     CDS             69377..69646
                     /gene="fliQ"
                     /locus_tag="PC512_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliQ"
                     /protein_id="HDF2440159.1"
                     /translation="MSEFMIMSVLKNGMFTGAMIAAPVLIVSLVVGLLISVFQATTQI
                     QEQTLTFVPKLIAILLVVAIGGSWMLHTLISFTSEIFNMISLITK"
     gene            69658..71472
                     /locus_tag="PC512_000381"
     CDS             69658..71472
                     /locus_tag="PC512_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fused FliR family export protein/FlhB family
                     type III secretion system protein"
                     /protein_id="HDF2440160.1"
                     /translation="MIFVFIRIVAFFGTLRILFPAGTPALFKSLFAIIISILISSTMQ
                     IEYATNIDNIVLFTLYGVNETITGIMLGYITNLCFYSIRMAGSMMDQQMGLSMINMFD
                     PNSMTQTTLIDNLMNWTALMIFFSMDGHHVLIRGIRYSFELIPIGKPFVDNNIDYIIN
                     IFVQCFLTGFKIAIPIVLCLLMADFILGLISRSVPQLNVMIVGMPLKILVGIALFIIS
                     IPLIVNQISHLLSQIPKMYEGTFALAPMFFMGSADKTEEATPKKKGEQRKKGNIAKSR
                     ELPVAMTLLAFTLLVPTLFSYVVDTLKSSLNYFLSLDFYMNINYSNLEKLVIAGLMDF
                     FKIFLPIAIPFLVLGIIANLFQVGILFTGETLKPNLSKLNPISGFKNMFSMRSLSTLI
                     KDTAIISILAYIGYTFFQDNYLDILKLGNIYLPTLMYTVKDLVYSILSKICVAMIAIA
                     VADYVYQRYSHKKQLRMTKQEVKDEYKNSEGDPEVKAKIKQKQRQISSQRTMQAVPSA
                     TVIVTNPTHLSIAVRYEKGKDQAPVVVAKGADYLAFKIREIAKGNNIPIIENKPIARL
                     LYKQVEIDQEIPEDMYQAFAEILVAVYKIKNRYKVPKR"
     gene            71481..73556
                     /gene="flhA"
                     /locus_tag="PC512_000382"
     CDS             71481..73556
                     /gene="flhA"
                     /locus_tag="PC512_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhA"
                     /protein_id="HDF2440161.1"
                     /translation="MNKFNLKENMDVIVAFGVVGIVLMMIVPLPTFILDILLAINISL
                     SVLILLMTLFTTNVLDLSIFPTVLLVTTLFRLGLNLSSTRLILTQGYAGEVIEAFGSF
                     VVGGNYVVGIIIFLIILIVQFVVITNGSGRVSEVTARFTLDAMPGKQMSIDADLNAGV
                     IDDKTARKRRKELQQEADFYGSMDGANKFVKGDAIAGLIVTAINIIGGIVIGAVMLNM
                     TLMGAAQTYVRLTIGDGLVSQIPALLISTSAGIIVTRASTDENFGDLVGKQLTAIPKA
                     VMMTGCVLIVLGMMPGLPKPAFFSLGIGAIAAGYFLGREKKDTLEDLEFEKPDMVNPD
                     KNEVEDVTNLINVESIEVEIGYGLISLADESAGGDLLQRIASIRRQCAIDMGIVVQPI
                     RIRDNLQLNPNQYNIKIKGNVVGGYEIMPNMVLCMDPMNQGFSIFGIKTIEPTFGIEA
                     LWIESDKVEDAELKGYTVVDSSTILITHLLDIIKSNAHELLGRQEVKTIIDAARENYS
                     AVVDELIPDLMTLGEIQKVLKNLLREKVNIKDRVTILETLADQSRNTKDIELLTEYVR
                     IALARSICNNLVDDDKTIVVATLSPETEELVSNNLQRSVNGTYPAVDPENTNKIFESI
                     QEVMSNVYFNHNIPVIVVSPKIRAPFRKLVEIVYPNLTVLSLNEIPNDIKIKAEGVVS
                     IYDDEKVYS"
     gene            73531..74547
                     /gene="flhF"
                     /locus_tag="PC512_000383"
     CDS             73531..74547
                     /gene="flhF"
                     /locus_tag="PC512_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhF"
                     /protein_id="HDF2440162.1"
                     /translation="MMTKKYTANTIQDAMNLAKMELGDNITLIDKKEVRKSGIQGIFS
                     KKDIELTIGWEKRENVEQKDLKREIEQLKSIINNMGFDNKNDNDIDKICKNLLSLELN
                     EEIVESIRIDLQEMKFNGIDTSKNLVEILKKKIKIENQVINGKIALVGPPGVGKTTTI
                     AKLAAKLVFEENKKVGVITIDTYRIGAVEQLKIYTDIMNIPFKGVISPDEMELALDEM
                     KDCDVVLIDTTGRGYKNSMQILEIKNLIDKAETDNIHLVLNCTTRESDTKAIIDSYRN
                     VNFKSLIITKLDETITYGSIFNIMNYAQKPISYITTGQNVPDDIIKPNEDKIIRLLLG
                     VESI"
     gene            74544..75422
                     /locus_tag="PC512_000384"
     CDS             74544..75422
                     /locus_tag="PC512_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MinD/ParA family protein"
                     /protein_id="HDF2440163.1"
                     /translation="MIDQAQILRKIAMEKRGLDEFIVENENVPKIITIASGKGGVGKS
                     NLATNLSICLTKLNKKVLILDADIGMSNIDIIMGVNVKGTIIDVINGEKNIEDIISQT
                     KYGVNIISGGSALNHIEDFTEAQRNKFIHSIEQIHDVDFIIIDTGAGMSKSLLSFIYC
                     STEFFLITTPEPTSLTDAYSLLKAISNFGIKRSANIIINRVIDLEEAKSTYKRIKMVV
                     DKFLNLNLELYGYIIDDKKVSLCVKKQIPFILEYPTSIASKCIIAIAKRMVSQSREDI
                     VDNKSFLRKMFSIFKS"
     gene            75436..76137
                     /locus_tag="PC512_000385"
     CDS             75436..76137
                     /locus_tag="PC512_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliA/WhiG family RNA polymerase sigma factor"
                     /protein_id="HDF2440164.1"
                     /translation="MNREELIKENMPLVKSIARKFFIPGKGFEYQDLVNSGVIGLIDA
                     INKFDAEKGAKFSSYSYIKIKSAILDEIRNQSPISKHNLTKVNKYNRVVEKLQSKLLR
                     EPTSYEIAKELKVSEKELHDIESNIDMLNIVSLNYVIFEDTNETVQDVISDREEEAPE
                     NIIEEEEKLEILSKAISNLNEREKLILSLYYYEDLNLKEIGKVLGVSESRVSQLHRKS
                     IRNLRNKIKELKYSI"
     gene            76153..76575
                     /locus_tag="PC512_000386"
     CDS             76153..76575
                     /locus_tag="PC512_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein"
                     /protein_id="HDF2440165.1"
                     /translation="MIQIILIVVSILIIVTIVINLHKESKNKDNRYFDKIFEQEYEAN
                     DRLIIAEKRRFFLDKVLAEKRINSHIKVYENYNLIKANEERKENIFIESKKEVRQENE
                     LSLKVKHLISSGYDDVEICKMLDIGKGELLLIRSCYKI"
     gene            76560..76745
                     /locus_tag="PC512_000387"
     CDS             76560..76745
                     /locus_tag="PC512_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein"
                     /protein_id="HDF2440166.1"
                     /translation="MLQNIRILLCDKKVFLGIGIGILISTLCIMLFSNNDMSKAEIEK
                     KARALGMKYTSEMKVLE"
     gene            76786..77559
                     /gene="flgG"
                     /locus_tag="PC512_000388"
     CDS             76786..77559
                     /gene="flgG"
                     /locus_tag="PC512_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgG"
                     /protein_id="HDF2440167.1"
                     /translation="MIRGLYTAVSAMITNQQKQNVVVNNLANMDTNGYKSKQLLTKSF
                     DELKLEGYNNYANGTKQKQIIGDISPGISMDETITNFNQGPIKTTDNKMDVAIQGKGF
                     FLVSDAAGNQFYTRNGNFRTDNQGDLITSEGYYVLGTNTATGAVGHINVGNQKFEVAK
                     DNTISLDGNAMYKFNIVDFNNYNNLKKEGDNLYSGGGAMKVNNALTIQSAIESSNVDM
                     VSEINNMMTISREYEANQKIIQAMDSKLAKIASEIGSVR"
     gene            77580..78341
                     /gene="flgG"
                     /locus_tag="PC512_000389"
     CDS             77580..78341
                     /gene="flgG"
                     /locus_tag="PC512_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgG"
                     /protein_id="HDF2440168.1"
                     /translation="MYTMFYTSKTALSANQSKLDIISNNIANSDSTGYKKINMEYSDL
                     VDEVLNRPSYPTNGNDISTGTGAKATAPMRNYEQGALAPTDSKSNLAIDGEGFFRVIR
                     KDGTYAYTRNGGFNVDALGKIVDDNGNILDVQFDAGYNYNNTNIDSTNLTVSRNGELF
                     VDNKKIGKINLYQPIGTQNFISEGDSLFVATDAAQIKQVEKVDIVQGYRERSNVSLQE
                     EFVDLIATQRAFQMNSKGIKTADEMWQIANNLRAK"
     gene            78364..79245
                     /locus_tag="PC512_000390"
     CDS             78364..79245
                     /locus_tag="PC512_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HDF2440169.1"
                     /translation="MNDMKEYDFGKPQSYSRENLTCLNFLLAEFCKKYKNYIIYELKC
                     NSSMVVDSIDQVNYQTFLDRVTSSCVVVQNAMEPVMKNFSFRIDRSVADMWIDITSGG
                     TGVVKDNDRELTELDKKVLLHLMDDLVRNMHLFEGFENIQVLDTHTHINLPQLCSPTA
                     PVCVVDLKVLNDNEYIGSVSLCFPYNGLEALLESISVIEFFDNDVGDDSEEFTQKIYN
                     SVSNIELSVIAEIGKVSINVEDLLKLEVGDVIVTNKKINDYIDIFVENSKSYTATPGF
                     ISSKKGVKINDAVGKEV"
     gene            79248..79622
                     /locus_tag="PC512_000391"
     CDS             79248..79622
                     /locus_tag="PC512_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HDF2440170.1"
                     /translation="MDNSNLISDEEAKMLLNDKVESEVDGDDELALDVSEVNRNNIQR
                     ILDLKLELSVVIGRTKMTLRDILNLHKGSLIELDTLADQDVEILIDNKVLAYGKVVVV
                     DLNFGVKITSIVSEEDMVKSLV"
     gene            79654..81057
                     /locus_tag="PC512_000392"
     CDS             79654..81057
                     /locus_tag="PC512_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HDF2440171.1"
                     /translation="MVLILNLNDIKKDILKLNKKDSCSLYNESINNINNNCISTGLKF
                     LKQARDLNPDDVDILNLTGLVNLLKCNFDDAVESFYKSSLCEKTALCEKYINMLTSEE
                     FLIFFEKYNQLIRLINKGMYKEAIQGFKLITDQYCDLIEPYELLALLYDKEEEYIKFD
                     ECLEVLKIIDKENYLLNQENNTLYMYNSANIQTKSNIKVDDYKNEFLHKSSSNHKIND
                     YNDVTKEKSSSKNQKSSDSNKKKSIKKNKYLYIAIILGILLVGQSIYSSYKMNNLTDK
                     ISKNNETKNEESIDSNLTKKENNIEENEDMSKASNINKSNKNINKEDDVKSKKNTVEN
                     EDDKDSDLFTEDELMSKANTLKSEKKTKSSIQLYKKVADIGENKGNTSEATYQVAILS
                     EKLKDYKTAEEYYKMYVENYSEKDAYFDESYYNLGMMYYNNGDLKNSKLTLKKLVNKV
                     PNSMYNNSKVKEILKEE"
     gene            81173..83110
                     /gene="htpG"
                     /locus_tag="PC512_000393"
     CDS             81173..83110
                     /gene="htpG"
                     /locus_tag="PC512_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone HtpG"
                     /protein_id="HDF2440172.1"
                     /translation="MEFEKGSISIHTENIFPIIKKWLYSDKDIFIRELISNGCDAVSK
                     HKRLVSLGEISENKSSDYKITVSVNKGEGTLKFIDNGIGMTEEEIKKYINQVAFSGAE
                     DFFNKYKDKMEESNDIIGHFGLGFYSAFMVSKKVQIDTLSYTEGATPVRWISEGGTEY
                     EISESDARNDRGTTITLFIDDDSKEFLDEFTVRGIINKYCSFLPVEIYLEDVERLERE
                     AKEAEEKAKKQKEDGKEEIVDAKVIEPLNDTNPLWLKSPKDCTDEEYKEFYRKVFNVF
                     DEPLFWIHLNVDYPFNLKGILYFPKLKNEFELTEGKVKLYNNQVFVADNIKEVIPEFL
                     LLLKGVIDCPDLPLNVSRSFLQNDRDVSKISKHIIKKVADKLKSLCKNEREEYNKFWD
                     DIQIFIKYGCLKDESFYEKVKECILFKTIDDEYITLQDYLEKCKDKHENKVFYVSDKE
                     QQSQYIKLFKEYDLSAVVLNSSIDTHFISFMEYKENGVKFNRIDADLSDVLKDKNENK
                     DSEENKEEIAKIEGLFKEAVGERVKNYSVEGLKNEDTPAMVLVSEQSIRMAEMQSRFA
                     GMDLGMNFEEEKTLVINENSPIIKKLVSLKDDEEKKDKITLICNQIADLALLSNKELK
                     PDELDSFVQRSNKLMSLLIEL"
     gene            83497..84627
                     /locus_tag="PC512_000394"
     CDS             83497..84627
                     /locus_tag="PC512_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HDF2440173.1"
                     /translation="MNFNYNLPVNILFGRGRINDVGKEVSKYGKKVLIVTGKNSTKKT
                     GLLDKTIDLLKDSKIEYEVFDRVEQNPLITTIYSGVEIIKSTGCDCVLGLGGGSIMDA
                     AKSIAFSYKNPGDLNDYIFGIRQGEEALPIILVPTTSGTGSEGNCFAVLTNSETKDKK
                     SIKKNSMYAKASIIDPELMVTMPKHIIASVGFDALAHNMEAYLSNGRNPLADVQAIYG
                     IELISENLIKVYNDVNDLEAWEKITLASTIGGMTIGTAGTALPHGMEHPVSGLRDVMH
                     GKGLAALTPTIIESSWDSDIERFGNISKVLGGTCAEDCSDAIRNFLKKIDLDIKLSDL
                     GIEKSDIDWLTDNCMKISVANIKRHPKYFNKEQIKEMYHKSL"
     gene            84854..85876
                     /gene="splB"
                     /locus_tag="PC512_000395"
     CDS             84854..85876
                     /gene="splB"
                     /locus_tag="PC512_000395"
                     /EC_number="4.1.99.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore photoproduct lyase"
                     /protein_id="HDF2440174.1"
                     /translation="MFNPKRIIFEKGTLDTDVGKKIYNKFRDNKDVEIINISSNRIKE
                     HIPGENLYEQYRSGKQTMVVGIRKSLKFQTCKPSANYQLPLVSGCMGRCEYCYLNTQL
                     GDKPFIRVFVNVDEILEQTKKYIEDRKPQVTIFEGAATSDPVPVEPYTNSLKKTIEFF
                     GREEKGRFRFVTKYSDVDSLLDAEHNNHTEIRFSINTPRIINEHEHYTASANKRIESA
                     VKLARAGYQIGFIIAPVFLYEGWKEEYKNLIISIKEALPKDFDKKIIFEVISHRYTTK
                     AKNRILEIYPDTLLPMENEDRKFKYGQFGYGKYVYDKEQLDDMKEFFLKEINGVFKNS
                     LIKYII"
     gene            86058..86969
                     /locus_tag="PC512_000396"
     CDS             86058..86969
                     /locus_tag="PC512_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF2440175.1"
                     /translation="MHAWESIQITLDLIEANLSEEISINELANKANLSPFYYQRLFKR
                     LVNKTVMEYIKLRRLARASEYLAEHKNRILDVALNFGFASHETFTRSFKKAYGLTPEK
                     YRANPVKLNHFIKPELILNYAMVDEGVPLIADDIVIEVNRKTLSNPRTFVGIEIEVPI
                     CQLVGGETTGIAIVEELWMKLGSQRHNIPNQIPGGNEFAALYMGNAKEGNCMYMAGVE
                     VESGTSVEGYSTFELPAKEYLVCGFEAENFNELVNSAVFKADKFMERWMKKHNLTTTD
                     FAIEMYYPTTPEAAYLEHWIVPVPIEQ"
     gene            86984..87400
                     /locus_tag="PC512_000397"
     CDS             86984..87400
                     /locus_tag="PC512_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HDF2440176.1"
                     /translation="MNWQDAFFQDTKPTFEQINEFINNPLWDKLNKTLVSTYNVEPKL
                     EYSKCSMQRGWNVKYKKRGKSLCTLYPQEGYFKALVIVSESNRVEVDLFINTCCDYIK
                     KIYNEVNFFNGSKWLMIQVDSLLVLNDMLELIKFRA"
     gene            complement(87500..87892)
                     /locus_tag="PC512_000398"
     CDS             complement(87500..87892)
                     /locus_tag="PC512_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2440177.1"
                     /translation="MSINTEKNITKNVEELTCPIRYALDIVGGKWKLPIICMLAVENP
                     IRYSSIKRKLDGITNTMLAQSLKDLESTGIVHRKQYNEIPPKVEYTLTSKGKSIVPIL
                     QQFANWGATNMQEKNTCGLSCKECRKIK"
     gene            88033..88428
                     /locus_tag="PC512_000399"
     CDS             88033..88428
                     /locus_tag="PC512_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HDF2440178.1"
                     /translation="MKALEFLNKARVYYLATVDENNQAHVRPLGFVMEYNGKLTFCTS
                     NQKDMFKQLIFNPKVELCCIDQNLNTLRILGEAVFVTSKETQAKALEIMPSLGQMYSV
                     GDGKFEIFSIDKAKVSCCSMSGKKIDVEL"
BASE COUNT        35590 a         9379 c        15805 g        27803 t
ORIGIN      
        1 atgaataata ttttacgctt gaaaaaacag actaaatacg tagaatattt ggtaaaactt
       61 acctgtatta attgcaatta gaaggttcta ttattaattt aaattaaaat taattcaagg
      121 aagtgacata aatggaacaa caagatgtaa tagacaaact acgtaggggc gaattaatgc
      181 taatggagta tttgtggaat aaaaagtcta ttttatcaaa aaaagaaata atagaagcaa
      241 tgaaaaagag atataagtgg aggaaaagta ctacagaaat tcttttaaaa agattggtaa
      301 agatgaaaac attaaaaaag aagaggatag gttttcagtt tagctatgaa gtattagtaa
      361 ctaaaaaaga atatttaaat gctagaaaag aagaaagaga tataagtaaa tatgataatt
      421 tttttgcacg aatattcaca actatacata aaagagataa gatgacagaa gaacaactaa
      481 aggcatttat aaaaaatatg gaaaaaattg gaaaaatata atttatatat atcaattaat
      541 tttaaattaa atttgttata atatttatat atattttaat atgcagaaat ttacaaaaaa
      601 gggggtgcat attatgggat ttaaaaaatt acctgattca gaattaaaag taatgaagtt
      661 tatctgggga ttagaaaaaa aagtagcttc aggagaagtt gtagaagcta tgaaacaaac
      721 ttatggttgg aataaaaata caacactaac aatattgtct aagcttgcaa agaaaaacta
      781 tttgtattct caaaaaacaa gcaagtgtac atattatact atcgctgtaa gagaaaaaga
      841 ttatttaaaa gttgaaacaa aaaaattctt tagttttttt cataataatt ctttaaaaag
      901 ttttttcact gctttaaatg atgaagaaaa tttaagtgat gataaattag atatgttaga
      961 ggaatgggtg aaaaattggg aagaagatga ataaaatgaa tgtgatacta aaatgatact
     1021 aatatgtttt atagcgtgtt aaaaaatata gaaaatatag aaataataga agaaaattaa
     1081 tgtaatagat aaggttttat cagattaaaa agaaaatcaa tagaatggga ataaaatata
     1141 gaatgccaaa aatccacata aatacaggat ttgaggtctc tcttacttct atgttatact
     1201 ggtttgatac tatcaatatt tgccagtatc ttatggatta ataagcaaaa aacatcctgc
     1261 tgaatgataa attcagcggg gtgtttttat tttgttttag aactcctttg ctctgaaact
     1321 cgaagtattt aacactgatg attttgttat cttttagttc cttttgtgtc atgctctgaa
     1381 agacaaattg atacaataaa aaagtaattt cttaatcatt gatggagata tgtgtttatg
     1441 ttactcttga tggtaatttg agtaatattg ttcatagctt tttatattca cttaattaga
     1501 aaaccatttg gtataatcat aaataaactt gatgatataa tagaaaagat ttataattat
     1561 tagaagtata taaaagtatt ttatgtctat gaaatgtatg tctataaaac atatagatga
     1621 cttttgtata ttaatgtatg aatattgata ttatagaaga attgagttgt caatgatact
     1681 aaatcaaata tttatagaag ctggagggat tatgagaaat aaaataatta taggaattac
     1741 tttttcactt gtattactaa tgtctggatg tgcttcaaaa caaaccgcag aaataaacgt
     1801 attagcaact actgatttac atggagttat accttatgag ttaacttctt atgtaaaaga
     1861 agaaagaaaa aaagataaaa atctaacttt agtagatgca ggagattttt ttgatagtgg
     1921 agaagtgttt ggttctagca tggatagtta ttttagtgct agatataaag atggtgataa
     1981 taacactgaa agttatattg agacgcctat ttcaaaagat atgaaagagg taggttatga
     2041 tgttgcagtt cttgggaatc atgaatttat atccaacaat aaattttatc tagataatat
     2101 gatatctgat tttgagaagc aaaaaataaa tattttatcg gcaaatacgt ataaaaaaaa
     2161 tggagatagt tatacaaaac catacataat aaaaaatatt aatacacctg aaggaaacgt
     2221 aaaactagga attttagggc ttactataaa agaagttggt gagaggaaac agtggaaaga
     2281 tggaaaactt gttgactcta agtctttaga actaaaagac caagagggtt acaatggtga
     2341 attgtatatg aatgatttag tagaagatgc taaaaagtgg gttggtataa tggaaaaaga
     2401 gaagcctgac attatagttg ctgtggcaca tacaggtgag aaacctaaga aacctaaaaa
     2461 cccaggaaat agaatacaag acttagctca acaagttgat ggaattgatg ctatagttgc
     2521 aggtcataat catgttcaaa ttgagcaaca tgattataaa aataaatcag gagaaaatgt
     2581 tatagttact gagccaggaa agcatgggga atgtatttct aagattaatt ttaaattaga
     2641 aaaaaacaat gataaatgga atatagttga caaatctagt aaattaatta aatttgaaaa
     2701 aaatcaagaa agtgataaat ttggagaatt tatttcttca attaataaag taagtaaaga
     2761 taagaaagaa ataagattat cagaagtaaa gactcctgaa tgggataaaa tatatgtttt
     2821 taaatctgga acatctgcag atgatatata taaaacaata ggatataaat ggagaaatat
     2881 atcatctcca aagggtgatg acatggtgca gattgttgta atgaataata ataagcctgt
     2941 tagctatgta tatggtgaag ctgaagttat gccaattaat ataaaatgtg atgaatcaga
     3001 gtataaagat aatgttgtaa ctatttatcc taataaaaat gataaattta aaattgaaaa
     3061 aggtaaacaa gaatatagta ttaatttaaa acatatacaa tagaaacttt tatcttattt
     3121 aagtttagat tgtacttaaa ataaagtgtg tattatttta aaaattgatg ataattaaaa
     3181 tcacaacatt aaagaatagt acacactttt tatgctaaaa aatagaatgt taaaaaatta
     3241 aacctttaaa ttaaagtaca ttgcttatat tatccaatat tattttcaaa ggttgtgtaa
     3301 tatttttatc cttatgtaat attgctaaca ttttattttc catatctatc ccatctaatt
     3361 caatcaatcg caatttttta tgtaagagtg aatctaataa taaattttct ggcaaaatgg
     3421 ttatacctaa ccctgcttgt gcagctttaa taagtgcaaa agaattaaca ctttcccaaa
     3481 caggataagc tttttggttt gaaagagata atacactgtc caaagtattg cgaatggcac
     3541 ttccttgctc acgtaacaat aacggaaacg tgcataactg tcgtagagat aaggcttgtt
     3601 tagtattggt ggtggttatg caatcatact tttaatccaa gagaaagtag taaatcaaac
     3661 tggatggata agtgagaaaa tgtttacaga tattataact atttcacaaa tgacaccagg
     3721 gccactggct gttaatactt ctacttttgt tggacttcaa attggagggt tttggggagc
     3781 agttgcagcc actttaggtt gtgtattatg tggtgtagta atatctctat ttttatataa
     3841 tttttttcaa aagcatcaga actctactta tatatttgaa atattaaatg gtctaaaatc
     3901 agcttcatta ggtttaatta tctcagctgc ggctacaatt ataatccttg cattatttgg
     3961 gacgaataaa gtgtacttca attctatatt tgagatgcta aactggactg cactaataat
     4021 cttttttgtt acactactga tagtacgtaa gtggaaaatt aatcctattg tgattataat
     4081 aataagtggt atactgggaa tattttttta tttataagtt tttggtaagt agaggatatc
     4141 tattttttta tatcttaaat ccaaatagcc aataaagtaa ggccatttgg atttttaata
     4201 aattctgaaa agataatcag aaacccatat aacatttaaa ttatatcact ggttttctac
     4261 aaaccaatca taagcttctt ggcaaaattt ctcactatct atatagtaac tattatgaac
     4321 attattaatt tcaacaagtt tctttttaca ttttagtgaa ttataatagc tatcaaaata
     4381 ttgggtttta aaatatctat catgaagtgt tttaaagaca agagtaggta tgttgactcc
     4441 atcttttatc ttactatctt ttgcaataaa gcattctaac attgtattaa ttatctttgt
     4501 actatttttc caaatatgag gatttttctt ttcaaatatt ttataaaatt cattatcata
     4561 gacttcatta taacctttat atttaggtgg ttttactgtt atgtgaaaat taggaagaaa
     4621 cttaaagaaa aagtttaata atttaacagt gagataggta tagcctactc ctgttgtgtt
     4681 tttataatca acacaagcaa actgagcaaa actttttaac ttattgtctg aacatgcata
     4741 atattgtgca aacataccac caattcccgt attcccatat agatgtatgt tggaagaata
     4801 atttttttct atgtatgtaa tgacagaatc taagtctttt acaattgaat tgcgagaaaa
     4861 atctttttca tatccatcac ttttccctgt tcctgaaaaa tcaaaagcaa atatatttac
     4921 attatgtttg gcaagtggtt catatgcttt ttgcatctca agcgtagtga caataggagt
     4981 atgtgtaaca acaatattca tggatgattt tctggtaata aatgagttac aaaaaatcat
     5041 tgtatctcca tttggtattt ttatatgttt ccaactcatt tgattttcct ttctctatta
     5101 taaaatataa taatttttat gttctgtttt atatattatt catattttat cacagataat
     5161 atactaaagt taattttttt attgtacacc tattataata attcttctat aatataagac
     5221 attctataat tttatattta agttcatgtg tatttaattg tttttatata aaatgtccag
     5281 taatactatt tggatttatt tttatttcat caggagttcc agaagcaaca atttcccctc
     5341 catttattcc actgtctgga cctatatcga taatccaatc agaagcacgt ataacctctg
     5401 tattgtgttc aataattaaa agtgaatgct gttcatttac aagttttcta aaagtaatta
     5461 acaaattttc tatatcttta aaatgaagtc cagtagtagg ctcatccaat atgtacagca
     5521 ttcgtttttt agtttttgtc cctaattctt ttgctaattt tatcctttga gattctcctc
     5581 cacttaatcc taatgtattt tgtccaagct ttagatatcc aagtcccact tcatctaata
     5641 aggagagttt tctatatata tcagagcaat cgctaaaaaa tgtttttgct tctgctactt
     5701 ccatgtcaag tatatctgca attgtctttc ccttgtattg tatagacagt atttcttttt
     5761 gatatctctt accttgacat tcactacaag ttacccattg gtctgccata tattgcagaa
     5821 taatttttgt tttacctaat ccttgacagt ttgggcattg cccctttttg ctattaaagc
     5881 taaaatagct ttcatccaat aatttttgtt ttgcttgtgg agtttcagca aatagagaac
     5941 gaatttcatc aaaaatattg atatatgtag caggtgtaga acggctagat tttccaatag
     6001 gtgtttggtc cattaagata aaatcatcaa tagcatcaaa tccagtaaat tcagtataat
     6061 ttttatctgg gatagatttt tgtttcaatt tttcttctag agcaggaagt aaactgtgaa
     6121 atacaagaga gctcttacca gaaccactaa cacctgtaat agagcacata cagtttaagg
     6181 gaatttctac atcaatattt tttaagttat ttgcatggca tccttttaag cttaaccatt
     6241 tacttggtat aattttattt tgtgaactta ttttattgta tgtgcttaaa tatttacctg
     6301 ttatagagtt tggatttttt ataatttctt gggttgtacc ttctgcaata atgaaccccc
     6361 cttttgtacc agcacttggg cctacatcaa taatataatc agcagacagt attgtatctt
     6421 tatcgtgttc cacaactata acagtattac ccttatctct tagctcttct atcattttga
     6481 tgattaaatt atggtctctt gggtgtaaac caatagatgg ttcatctaaa atgtaggtta
     6541 agcctactaa ttcacttcct agctgacttg ataatcgtac tctctgcagt tctcctccag
     6601 ataaagttgg agctgttcta tctgttgata tatagctaag acctaccttt aatagataac
     6661 taactcgaat ttttaattct gttaagatat catttaccaa agagagctca tttttttgaa
     6721 gttgatttgg taattcacac aaccaattcc ataactgttc tatcgtcatt tttgttagtt
     6781 cagggaagcg ataacctttg attgtagtga atctagcctc aatgcacagc aattcgccac
     6841 cacatgtatt gcaaggaatt ttgttcatat attgatgcaa ggtattattt tcagaactag
     6901 attctctaaa aagtctttga atgtggttga ttgctcctga agcaggtctt ctaatctttg
     6961 attctcgtcc ctttgattca aagctaaatt catatatctt atcgtctgta ccatataaga
     7021 ttgcatctat aaaatctctt ggtaattcat tccaaggtat atctaggtct atatttttat
     7081 cttttgctat tgcatataat tcacctacca tccaattacc atttggcttt ttccccttca
     7141 attttccaaa atagtaagta gctccatcta atattgaaat agttgggtct tttacaatca
     7201 attgaggatt aacttgatag gtaaaaccta atccattaca atcgtgacaa gctccagtat
     7261 gggagttagc attgaaggtt gaagtattta tcttagaaaa aatagtttga caatgtggac
     7321 aataattttt tgtattattc tttttttcta atggaatttt acaatatgga cagtaacttt
     7381 ttccgattga tacaaataac attcttaaat aatcccaaat gcttgtaaga gtaccaacag
     7441 tagagcgagg attttggctt ccttttttct gttcgatagc tatagtaggg gttaatccct
     7501 gaagtaaatc aaattccggt ttttgaagct gttctgaaag ttttgctcca ttacttagat
     7561 tttcaaaata acgtcttttt ccttcttcat aaatcgtatc gaaagctaaa gaagattttc
     7621 cactaccact tacacctgta ataacagtta tttgattttt tggaattgta acctcaacat
     7681 cctttaaatt gttttgcctt cctcctttta aatagataga gcttttatta tgacaaagtg
     7741 aatttttaat tgatttattt attgattttg taaatttgaa tttcttttcg agttcaagag
     7801 gattgcctaa ttcttttatt tccgaaatgc ctaatatttt taactgagaa aagattgatt
     7861 tcaaataatc ttcaggcaat ttttctatta acaaattaag gtcttctatt tttatatttc
     7921 cgcttgataa tatttctgcc atttcatcta ataaattttt ttctgctctt gttaattgat
     7981 tgtatttttt ggaacttaat tctgtccata aatcccatgg aagcaattct aaaccaatca
     8041 tattattaaa gtcatgtaga agattaccct ttacagaatg ccaacctttc caatttttat
     8101 tatatccaaa gtcatcttga tgagcatgtc cttgccgaca tcttatccag gcttctgaac
     8161 cagttaaaaa accatctgtt tttccgacat catgagtgtc aaaattaatt tgaaaataat
     8221 ttttttgtat gtcatctatt tgtgcatcta ttcttatcca tctctttgtt agagtatcat
     8281 agtattctac aagccagtgg tcttcataag taagctcact ttcaaaataa ttagcaaaac
     8341 ctgctctcat tctagcctca aaacctcgat atcttaggag cgatacaaga agtaaagaat
     8401 aatctctgca cattccaaca agcctttgtt ttgggtttct tggaatagtt agtgggttag
     8461 aatttatttc aaatattctt tttaacattt gaggaattgt acgaagcaat tcctcatcag
     8521 attgttgttt attaaaggat ataccatata attttccttg gtctccatga attactaggc
     8581 tttgaaccac ttttaataac tcaattggag tctttggtaa atcttgatat ttattttcaa
     8641 attttttagg atttgtgatg atgctttgat ttttatagtt atttattttc atttatattt
     8701 cacctctcta aatggatgat ataccctgac atggtgtcat atgcaagggc aatttaaatt
     8761 ttttggccaa aatttaaaaa taaataaaaa atgatacagt gataaattgt aatacaaata
     8821 tagtttcaaa ttgcatataa tataattatt taataaaacc attatctatg gaatgttaat
     8881 gaaatgttaa gatggcattc ttgaatatta agaaatagaa tactataata tagtgtgaag
     8941 gatttttagt aaaaaaattt gtaagtgtta atatacatta aaaaatagat ttataatttg
     9001 gaggaaaaaa atgaaattat caaggtataa gaaaaatagt ttagttctgt ctataatttt
     9061 atgttcactt attatttcaa tccttgtaat tactgttttt aataccgtaa aactacacaa
     9121 tatatctaat aaacaatcta aaaactattt aaatgatgta tctacacaga ttgtaatgaa
     9181 tgttgattct aaaatcaaat ttattttatc cgacttaaga ataatggcag attttattaa
     9241 gcaatatgaa ggtgatagtc gatatgagta tttatctaaa agaaagacta gttataagta
     9301 ttatgatgtt ggaataatag atttagaagg taaagctgag tttttaagtg gaaaaaagtt
     9361 tgacttaaag aatactgttt cctataaaaa aggaattgaa ggtaaagaat actcagaagt
     9421 aatagagtca atgggttttg ttctttatag tgtacctata tttaatgata atcatgaagt
     9481 atctagtatt ttaataggtg tatccaataa agaaagtatg aatgagattc ttaatataga
     9541 taactttaat ggaaaaggaa ctattgaaat tattaatagt aagggaaaac ctcttttcat
     9601 aggaaaaaat actgaattaa taaaggacct tagccataaa tataagagtt ctggagatga
     9661 accttgggca caaaagatgc ttgaggattt taaaaatgat aaatcaggga atattacaat
     9721 aacctcatca aaaggtgtac aatgcttatt aacttatcat ccaattacaa gaggtttaaa
     9781 tgattggcat tttcttctca tagtacctga agatgctgta cttggtgaac ttaataaatt
     9841 aaactctttt acaataacaa tgacatttat aattacatgt attattggaa ttataacatt
     9901 aattttatat attataagaa gaaaatatgt aaatcaaata gaaaatattg catatttaga
     9961 tagtataaca aatggtataa attcaactaa gtttagtatg ctagtcaaac ctttaatttc
    10021 agaatcacct gatagtactt atatgatgat agcaatgaat ataaaagatt ttaagctaat
    10081 aaatgattgt ttcggtagtg aaaagggaaa tatgacacta aaacatcttt acaatatttt
    10141 gtataaaaac attgatgaaa atgaagagtt tgtgtgccgt catgatgcag accttttcta
    10201 tttgcttatt aagaatagac cagtgttaga agccctggag ttattatata aaatagaagc
    10261 tgacacaaat tattttaata aaaataggga aaatccatac tttttaagac tatcagtagg
    10321 tatttacaca attgaaaatc ataatgaaga tttaattaca atacaagacc atgcaaatac
    10381 agcaagaaaa agctttaata aaactcatca aagtgatttt tctttttata gtgatataga
    10441 aagaaaacga ttaatatctg aaaaggaaat ttcaaattta atggaaaaag cccttgaaaa
    10501 taaagaattt tttatgtgct tacaacctaa aattgatata aaaagtggaa aaattagtgg
    10561 agcagagtct cttgtgcgtt ggaaaaattc agaaaagggc ataatttatc caagtgattt
    10621 tattcctctt ttcgaaaaaa gtggatttat atgtaagtta gatttatata tactagaaga
    10681 aacatgcaaa ttgatttcta agtggataaa agaaggtaaa gaagtgttga gaatttctgt
    10741 taatgtatca cgtcaacatc tgaatgataa attgttttta gaaaaatata agcatatatg
    10801 caataaatac aatgtaccaa catgtctgat agatttagaa cttactgaat ctattttctt
    10861 agaaaatcca gaagctatag atataataga ggatattcat tctaatggat ttaaatgttc
    10921 tatagacgat tttggatttg ggtactcatc attagggata ttaaaggatt ttaaagttga
    10981 tataattaag ttagaccgtt cattctttgt tagcaaaaat aatatagacc gtggtaaggt
    11041 agttattaag tctattattg aacttagcaa aaggctaggt atgaaagtaa ctgctgaagg
    11101 aattgaagaa ttagaacaag ttgagttcct aaaaaatgtg ggatgtgatt atattcaagg
    11161 ttatgttttt tcaaaaccat tattaatttc tgactttgaa aattttgcat atgaaaataa
    11221 taaaattaaa aatatccatt attaaatgta caagataaaa aatttaggca agttatataa
    11281 ttaaaaatat aacttgcctt ttttatttat atatttaata aaaatatatt tgcagatttt
    11341 gtaaaaataa ttttcaaatg ttgtaagttg tggctaaagc tttattgtat tattctgaat
    11401 atagaaagat agttactgtc ttagataaaa actgaaacat acataataat ataaaatttg
    11461 ctatattaat aactctaatt attttggaag gagggaaaat atgataagtg ggagaatgtt
    11521 actcatcatg aattttctaa aaggaaaaaa taagacaagt tacaaggata ttagcaaaca
    11581 acttagtata gaagaaagaa aagttagata tgatataaat aatttaaata ttgttttgcg
    11641 ttcattaaac aagtcagtaa tacaaaagat gaacaaaggt gtgttaatta ttcctgatga
    11701 cttccaagta gtatgtataa ataataacga atatgtattt tccttaactg agcgagtatc
    11761 tattatgaaa attatatcaa tgtttaaaat agataatcta aacttagaaa aattaagtaa
    11821 agaatttcag gtttctagaa gttcaattaa aaatgacctt aatgttttgt caagtgaatt
    11881 agaaagaaac caaataacta ttacttatga taaatctttt aaaataagtg gagaagaaga
    11941 cattatatat aagcaaagat tgaacatatt aaaatcgtat tcttatcttt ttggtaagga
    12001 aaaatctgat ttaagtgtat ttgagaagta tttagtgaat gtaattgaaa aaatattcaa
    12061 agggatttat ttgattgata tatataattg gtctatgaat ttattattgc aaatgggatg
    12121 gactttaaat gatgaatctt ttacatggta tgtgtcaaac attttccttt ttacatggta
    12181 tatacattca gatgaaaaac atcctttaga atctgcttca ttaagtgagc cgtgttttga
    12241 aaataagttt gaccaagaat ttgaaacaat tattcaaaaa aagttgacta aggaacaaat
    12301 ttttctgtta aagagttttg tattttttac aaataaatat gcaagtttaa acgaggatat
    12361 ggatttgatt agtacagaaa ttatagttca agacctaatt tacaatatgt cagaaatatt
    12421 agagattagc tttaaagaag atatgattct ttataaagga ttactcaatc atattgcccc
    12481 attgatagag agaatcaagc agaatataca gatttatgag gaattacttc atgtaatacc
    12541 agataaatat caatatgtac ttgaagctac taaggtttct attcaaaaaa acagagtttt
    12601 aagtcaaata aagaatgaaa atgaaacaat acttttggca atacatttct taggaagtat
    12661 acatagaaat gagaggaata actacaaaaa tatattgtta gtttgtggat ttggatatgg
    12721 tgtaattgct atgttaaagg atagtttagt aaatgattac cagataaata tagtagagag
    12781 tattccatca tataagttac aagattataa agactgggaa agtattgact tcattataac
    12841 aacatcaaag atagtaatag acttgcctaa aacaattatt gagataaatc catttttaca
    12901 agaagaggat tatttgaagt ttgaagaaaa agggataaaa agaaagaatg tcttaactaa
    12961 ttatatgtca ataaaaaaaa ggttggactt tttagaagaa gatgcccaaa aaagagtatt
    13021 aagtattata tgtcaagaac ttggatacag tgatgagaga atattattta gacaacttaa
    13081 tttaagtgat ttaataggga ttgataccat aaggataatt gatggagata tgaaatggga
    13141 agatgctgta aaatttagtt caaacatact tgctaattgt gattttgtat cagcacaata
    13201 tgctgagaat attatagata ttttaaaaaa tgtgggtttt tatgctgtaa aagataacga
    13261 atttgcttta ctacatggca atgatagttc attagtcaaa gtaagttcga taagtttatt
    13321 aatatgtaaa gaagcagtta gttttggaga taaaaaggtt aaaatcatat tttgcctagc
    13381 aagcagagat aaaaaagagc aaattcctgc aataattaat ctaactaaaa tggtttataa
    13441 gactaatttt attgctatgt tagaaagtgc aaagacaaaa gaagaagcag aagttttaat
    13501 tcataaatat gagaaggagg tcactgtatg aataaattag ttaatgtaaa atgttcattt
    13561 aaaatacatg ttaattcaaa agaagaagcc attatatcgt tagttgatgt agtgtcaaaa
    13621 gaaggatatt taatagataa aaatcaattt ttaaaagatg ttttaaagag agaagaaaca
    13681 ttgtcgactt atattggaca tggtataggt cttcctcata gtcaaagtgt aggtgttaaa
    13741 aactcttgta ttacaatagg aaagcttgat actcctattg aatggacaga agaaggagaa
    13801 aaagtggatt taatattttt gatatcagta acaaaagaca atgaaaataa tcttcattta
    13861 aagattttat caaaattagc acgtttattg atgcatgaaa gttttagaaa tcaaattaga
    13921 tgttcagatg aacaaactgt ttataatctt ataaaagaaa aaatagagga ggaagattaa
    13981 aatgagaatt ttaaagtttt tgcaaaaaca tcttatgaca gcaacatctt atatgattcc
    14041 atttgtggtt gcaggaggaa tattatttgc tttatcagta actttaagtg gacaagctgc
    14101 tgttcctgaa acaggctggt tggctaaact gaatcaaatt ggagctgctg gcttggcttt
    14161 attcattcct atattaggtg gatatatagc atttagtatg gcagataaac caggattagc
    14221 tccaggtatg ataggtgcat atttagcaaa agaagtaaat gcaggtttta taggtggtat
    14281 catagcagga tttatagcag gatttgttgt tttacaatta aagaaaatta aattagctcc
    14341 tacaatgaga actttaggtt ctatatttat ttatccttta gttggtacat tgattacagg
    14401 tggtataatt gtatttttaa ttggagaacc tatagcttct tttatgacat ggatgacaaa
    14461 ctggttaaat ggaatgtctg gtgtttctaa aattccttta ggtggaatct taggaggaat
    14521 gatagcctca gatatgggtg gccctataaa taaggttgct gctacttttg cccaaactca
    14581 agttgacaca cttccatatt taatgggtgg agttggcgtt gcaatttgta tacctccaat
    14641 tggtttagga ttagctacat tattgtttcc aaaaaaattt agcaaggaag aaagagattc
    14701 aggtaaagct tcactattaa tgggatgtgt tggaattaca gaaggagcta ttccatttgc
    14761 aacatcagat ccagttagag taataccttg tattatggct gggtcgattg taggaaatat
    14821 tatggctttt ttattaggat gtttaaatca tgcaccctgg ggaggtctga tagtgttacc
    14881 tgtagttgac aataggttgg ggtatattgc atcagtatta actggagcag tagttgttgc
    14941 ggtattaatg aaattagtaa aaaaagacgt gaaagaagat gaagaaattg aagaagattt
    15001 agatgaatca attgaattaa tatttgaaga attataaata taaatggaag gaatttgtat
    15061 aaaaaagtaa atataaaact ataaatttaa aggagataag aatatgaaaa ttgtagcagt
    15121 aacatcttgt cctagtggag tagcacatac ttacatgtcg gctgaatcac ttgaattatc
    15181 agccaaaaaa tttggtatag aaataaaggt tgagactcaa ggaagctctg gaatagataa
    15241 tgaattgtca cttaaagata ttgatgaagc aacttgtgta atattgacta atgatgttga
    15301 gattagaaat atggaacgtt ttaaaggaaa gaaggtagta agaatgagtg tatctgagat
    15361 aattaagaaa tctgatgcat taattaagaa aataaaagat acttttcaat aaaaattgat
    15421 ttattttaca tataactcaa agatgttttt aaagaaattt ttattaaaag catctttgaa
    15481 aatatcttaa aaatagaata aaaggagata tagtcatgaa aaagttacca ataaagactg
    15541 tcgtgcaaag attactaaac ttacaagaag aggggaaaag tgcaactctt ttaggaattg
    15601 gtcctatgtc accaaacttg ttacaagcaa gttttgaact agcaaaagat gatgattttc
    15661 ctttaatgtt tatcgcaagt agaaatcaag tagatgcaga tgaactaggt ggcggttatg
    15721 taaatggttg gaatcaggaa acttttacaa aagatattaa gaaggttgcc gacaaagttg
    15781 gatttgatgg tttatattat ttatgtagag accatggtgg gccatggcaa agagataaag
    15841 agagaaatga ccatttgcct gttgatgaag caatggagtt aggaaaaaaa tcttatttag
    15901 cggacattga agcaggtttt gacctattga tgattgaccc tacaaaagac ccatttgaaa
    15961 ttggaaaagt aattccacta gatgtagtac tagaaagaac tgtagaatta attgagtatt
    16021 gtgaaaacga gagaaaaaga cttaatctac cagacatagg ttatgaggtt ggtacagagg
    16081 aaaccaatgg aggtctgact tcaactgaga cgtatgaaac atttataact agactaaagg
    16141 ttgaactcga taatagaggt ttgccaatgc caacatttat agttggtcaa actggtactt
    16201 taactagaaa gacagaacaa gtaggaactt ttaattttag aaatgcttat gatttagctc
    16261 aaatggctaa gaaatatgga gttggtttaa aagagcataa tggcgattac ttagatgatg
    16321 taactttatt agaacatata ccatctcaaa ttattgctac aaatgtagct cctcaatatg
    16381 gtactgaaga aactagggca tatttaaaat tagcagaagt tgagtgtaaa ttagaaaaag
    16441 agggcttagt tgagaaaact tctaatatca gacatgttct tcttgttaat gcaattgaat
    16501 gtggacgttg gagaaaatgg gtagtaggag aacaaaaaaa tctaactact gaagagatat
    16561 ttaaggatga agttttatct aatgaaatac tagatattgc aggacattat acatttaata
    16621 atgatgatgt taaaaaagaa atagaagtgc tttatgataa tttaagtaag aataatattg
    16681 atggtcaaag atttgttgta gaccatatta aacgtccttt gcgtgattat gcagaatgct
    16741 ataacttaaa aggtgttact acgaggattt taaataaata ataggactta tagtggtgag
    16801 tattgttata ctaggtattt atagttataa ttatacttac cactattaaa tttaggagga
    16861 ctaatatttt gattaattta atttttgatg tagatgatac tttatataat caattaacgc
    16921 ctttttacac tgcatataat aaagtgtttt cttcaataaa ggatatttct attgaagatt
    16981 tatatatgag tagtagaaag tatagtgatg aggtatttca tatgactgaa aatggagaaa
    17041 tgccaatcaa agaaatgcat atttatagga taatgaaagc ttttgaggag ttgggaaatt
    17101 ctattacaga aaaagatgca caaagttttc aagatgagta tatatatcaa caatcacaaa
    17161 ttacactaat accagaagtt gagaggattt taaatttttc taaagaaaga aatattaatc
    17221 taggaattat aactaatggc ccatcaaacc atcaaagaat gaagttaaag cagttaaata
    17281 ttgaaaactg ggttgataaa agtaatattt ttatttctag tgaggttgga ttttctaagc
    17341 cagatactaa tatttttaga gtagctgaga atgttatgaa tttagataga gaaaatacat
    17401 attatgtggg tgattcttat agaaatgatg tattaggtgc taaaaaagct ggttggaaga
    17461 gtatatggtt gaaccataga ggacatgagg tagaagagtt gttttacaaa cctgattttg
    17521 taattttgga acataaggat ttgatatctt tatttataaa aatatgtagt tataaaaata
    17581 tgtagtaaaa aaatgttaat aatagaattg tataaaataa ttaataataa ctatataaaa
    17641 ttatatgttt agattgtgag caatctattt tatgttaaaa atagattatt tagaagaagg
    17701 ggaaatctta aaaaaatttg aatatcccct ttttattatt taattaaaat gaaatagtta
    17761 gaaatatatt ttatttagtt tagtcaataa cattttggga ttctttataa ctacatgtta
    17821 actgttgaat aggtttatca tatggtttaa cccatccttt attaatactt aattctgtaa
    17881 gtgctgtgtg accttctacc atttgagtta atgaagctga atatatagct cttaattcag
    17941 gtgtactact tgtcaatgca gaattaagat acatattggc agatgcttta gcagatgaaa
    18001 gcatacttaa cattattact ttatcgtcta tataagtatt gttcttaatt agattttcta
    18061 tcatatttct catgttatct atacctcctc agaaattagt atttcatttt caactataaa
    18121 ttgttgcata gctttaattc ttccttctgt tgctaatata ctagattctg attgtctttt
    18181 taggtcttca tctgatatta acatatttat tgctctttgc ataagtaatc cgtcagactc
    18241 catttttata actgctgcta aagatatttt ttcagtttct gaaagtattc tcatttaatc
    18301 atctcctata ttgtaattta tgctttaata gtatgtcttt cttttcaagg aaataaccat
    18361 tacacttttt tacagtattt tatattctct ttatatcaaa atttagtcga cctaatatat
    18421 taataataat tttgtaggat atttatcatt aaatatctat aaaataaatt atttgaatat
    18481 tcataaagca aaatttattt gtatgtactt cttcaagagt caatatgagt tttttcaaaa
    18541 aattaatttt tatgataatc attaagggct atatttttct taaagttgtg attatcatta
    18601 ttaatttaca ataaaattgc cgaaaagccc tctcctttag gtgtagggat gaaaggtaag
    18661 gtcttaatat aaaaaaagtt agaataatgc ttgtaatcta ataccgctac tgatacccta
    18721 tatttaggag gtgttagttt ttatgtataa atctaacaaa aatatagttt atgattgcaa
    18781 atatcatatt gtattttgcc ctaagtatcg taaacctgtt ttagttggcg aagttgaaaa
    18841 gatgttaaaa gaaatactac catataaagc agatgaactt ggagcagaaa taatagaaat
    18901 ggaaactgat aaagaacatg tgcacttatt aatatcttgt gaccctcaat atggaattca
    18961 taaagtagta aaaggtttaa aaggctttag ttcgagagta ttaagagaga actttccaca
    19021 tttaaagtct agtatgccta gcatgtggac taatagctat tttgtaggta ctgttggttc
    19081 tgtgagttta gaagtagtta aacaatatat agaaaatcaa caagttagga caaagaaatg
    19141 ataaaaactc atagagtgaa attaaaccta actagaacac aatttgaatt agtaagggaa
    19201 aagcaaatgg aaagtgctaa ctgttggaac tacatagtta acttatctaa agaatactat
    19261 tttgaacata aacaatggat taaaaagaat gatatacaaa agttaatcaa aggtaagtac
    19321 aatcttcata gtcaaactat tcaagctata tcagataaat ttgatgcaaa tagaaagact
    19381 atatcagaat taagaaaaaa aggtaatact aaagcaaaat atccatacaa gactaagaaa
    19441 ttttatataa taccttttaa agctagtgct attaatagaa atgctaaagg caacttaaaa
    19501 ttatcaatgt caaaaggcag gtatttagaa ttagatttta atgttgagaa tataaaaact
    19561 gctgaaatag tatggcgaaa tggatattat ttatactaca cttttgacaa tgaattaaat
    19621 ggagttgtag ccaaaggcac taataccgta ggtgtagact taggggaaat acattcgata
    19681 gctagtgtaa caaatgaagg tgtagggctt attctatcta atagagaagg cagaagtatt
    19741 aaacaattta gaaataagat gtatgcttat atatctaaaa gattaagtaa atgtaaaaaa
    19801 ggtagtagac aatcaaagaa gttatggaga ttaaaaaata agataagaag taaaacagat
    19861 aatcagttaa tgaatttata tcatcaaaca actagaaagt ttatagactt ttgtgtagag
    19921 cagaaggtat gtgaaatagt tcttggggat ataaaagggg ttgaaaaaga tactaagaaa
    19981 aagaaaagat taaacagagt taatagacag aaaatatctc aaatggagta tggtcgaata
    20041 aaggactata taaaatataa agcaaaagag caaggtattg aagttaagtt agttaaagaa
    20101 aactacactt ctcaaacttg cccaaagtgt tctaaaaaac acaaaccaac tggtagaact
    20161 tatagttgta cttgtggtta tgaaactcat agagatatag ttggtgcttg gaatatttta
    20221 aataaaaagc ataaatatgg tttagtagat tttagaataa atcataagca accaataaat
    20281 ttaaaagtat ctaccgtttg agccatgtgt gggcgaataa ctttaaggta gtagtggcga
    20341 agacaccgtc cgaagtagct tggctttgta accacctctg ttgtactgtt taagtataaa
    20401 taagtgtgtt agccaccaag aatccccttg ctttagctat ggggagtgtg tcaataaaat
    20461 actttaatga aaaatagcta actttaattg taggatattc ttaatatatt tgaaataaat
    20521 aaaaatattg aaggatataa tattcaattg gtatataaat aataaatgat agttaaattt
    20581 taccttagag gctaattagg tgtttagtca aagctaatgc ctttagaata caaatgtatt
    20641 ctaaaggcat ttttactatg tattttcatt tatattacta aacattatct atttttatat
    20701 acatttctat gtattttatt ttcatcaaat cggtctataa actcattttt ttcttcacta
    20761 tatccaatag atataagtgc ataaggaact aattttaatg gtaagtctaa agtttgtcta
    20821 actttattta ccactttatt tttaggaaat actcctgccc aacaagcagc tagaccttga
    20881 ttagtaactt ctaataataa attttgtgtg caagcaccta aatcttgtat ccatttacca
    20941 ggttttaaga atttatctct atttccaagc actactatac ataatggtgc aaattctata
    21001 tgctttgctc tatgctgtga ctttgagagc tgtttcagca gttccttatc atctactata
    21061 ataaattccc aaggttgagc attttttgat gaaggtgctt gcatagctga ttttagtatt
    21121 tcagttattt tatcttcttc tatattttta tctatatatg ttcttattga acgtctattt
    21181 tttataactt ctaacataca gattctcctt taaataaaat tatttctatt tatataatat
    21241 cattacttta aattttagct attacttata taaagaataa actttgtgtt ggttttatct
    21301 aagtaaaagt aacattcaga actaaaaaac aagactataa atccaaagta ttaattaaaa
    21361 aagaagtaat aaaaaataat atacaagatt taaaaaagag tattgggctt aaaatttaat
    21421 tagaaaacca attttgagat aatctgtttt ttattttaac aaaaaaacac aaataaagtt
    21481 cgatacgtag cgaatgaaaa aattacaaga aatatttttt ttaaaaaatt tcaaaaaaga
    21541 gttgataata tatgtatatt aatataaaat ttaaggtgta taattcgtat aataatacga
    21601 atgatttgta gtgtaaaata acttataaac ggagagggga agtctaatga aagtagcagt
    21661 agttatgggt tcaaaatcag attatccaaa attagaagaa gggataaaac tgcttgaaaa
    21721 atatggaata gaagttgtag caagagcatt atcagctcat agaacaccag aacaactttc
    21781 aatattccta aaagaaatag aagatgatac tgatgtaata atagcagcag caggaaaagc
    21841 agcacactta ccaggtgtaa tagcttcaca aacattaatt cctgtaatag gattacctat
    21901 taaatcatca actatggatg gactagactc acttttatca atagttcaaa tgccaaaagg
    21961 aatcccagtt gcaacagtta caatagactt aggtttaaac gcagctttat tggcattaca
    22021 aataatgact ttaaaatacc caaaattaaa agaggatttg aaatcatata gagaagagat
    22081 ggcacaaaag gtgttagaag acgacaagaa tttaaggggg tagcagaaat gttattatat
    22141 gaaggaaaag caaaacaagt atattctaca gataatgaaa atgaatatgt tgtttattat
    22201 aaagatgatg caacagcatt taatggagaa aaaaaagcag aaatatcttc aaaaggtata
    22261 ctaaataata agatatcaac aataatcttt gaaatgttaa aagaaaataa tataaatact
    22321 cactttataa aaagtttatc agatagagaa atgttagtta aaaaagtaga gattttacca
    22381 ttagaagtaa tagtaagaaa tattgctgct ggttctatct gtaaaagagt tggtcttgaa
    22441 gaaggtgtag ttttcgatga gccaattttt gaaataagct acaaaaatga tgcttatggt
    22501 gacccaatgc taaatgatga ttatgcagtg gcaatgaagt tagcaactag agaagagtta
    22561 aaattcttaa gagaagaaac tttaaaaata aatgagttac taaaagcatt tttcttaaaa
    22621 ttaaacctaa agttagttga ctttaaaata gaatttggta aggattctga aggaaatata
    22681 atattggcag atgaagtatc accagacact tgtagacttt gggatgtaaa tacaaatgaa
    22741 aagttagata aggacagatt tagaaaagac cttggagacc ttgtagaagg ttatacggaa
    22801 gtactttcaa gaatgaataa taaataggag gcaaatgtat gtgtggagtt ttagggattt
    22861 actctaataa agatgtaact aaagaactat attattcttt atattctatg caacacaggg
    22921 ggcaagaaag ctgtggttta gctcttttag atgatggaga aattaagtac aaaaaagata
    22981 tgggattagt tggagatgtt tttaaggaaa atgaattatc taagttaaaa ggaaatatag
    23041 ggattggaca tgttagatat tcaacagctg gaggaagtca tgtttctaac tgtcaacctt
    23101 tagttggaag ttgtagaaaa agacaattag ccatagctca taatggaaat ctagttaatg
    23161 caaattattt aaaagatatg ctagaagaag atggatatat gttccaaact aattcagata
    23221 cagaagtgat tttatatata cttgctagat attacaaagg ggatatagta gaaagtttaa
    23281 aagtgacaat ggattatata aaaggtgcat atgctcttgt aataatgagt caagaagaat
    23341 tggttgcagt tagagaccca catggattca gacctcttgt acttggtaaa aagggtgatg
    23401 aatatatatt tgcatcagaa aattgtgcaa tagatatact tggcggagaa gttataagag
    23461 atgtagagcc aggagagata atagtagtca aagatggaga actaaaatca tatttttatt
    23521 cagaaaatta taaaccagtt aagaaaagtt gtatatttga acacatatac tttgcaagaa
    23581 atgatgcaac tatagacaat gtaaatgcat atgaatttag aattaaatgt ggtgagagat
    23641 tagctcagaa tgaaactgta aaggcagata tggtagttcc agttccagat tcaggttggc
    23701 caggagctat tggttatgca aatgctagtg gattaaaaat aagtgaaggc ttagttaaaa
    23761 atagatatgt aggaagaaca tttataaaac ctacacaaga agaaagagaa atagcagtaa
    23821 aaataaaatt aaatcctctt tcaacaataa taaaaggaaa atctataatt ttagtagacg
    23881 actcaattgt aagaggaact acatctaaac aattagtaaa atctttaaga gaagcaggag
    23941 caaaagaaat tcatcttaga ataacttctc ctccagtagc ttactcttgt tactatggaa
    24001 tagatactcc aaatcgctct aaattaattg catcaagtaa caacgtagaa gaaatgagag
    24061 aatatattgg atgtgatagt ttaaaattcc tagatataga aggaatgtta gatgcaacag
    24121 aacataagtc tactttctgt aaagcttgtt ttgatggaga atacccagtt aagaaaattg
    24181 ataaggagga actactttca tgttaacata taaagaatca ggtgtagata tagatgaagg
    24241 aaatagagca gtagacctta taaaaggtaa aataaaagga acttatgatg gaaatgtagt
    24301 tggagattta ggtaacttca gtggattata cagtttaaaa gattttgtag gtatgaaaga
    24361 accagttttg cttgcatcta cagatggtgt tgggactaag ttaaaaatag ctcagatgat
    24421 ggacaagcat gatactgttg gaatagattt agttgcaatg tgcgtgaatg atttaatttg
    24481 tcaaggagca aaaccattat tcttccttga ctatatagct cttgggaaat tagtgcctga
    24541 gcatatcgaa aaaatagttg gtggaattgc agatggttgt aaaatgtctg gttgtgcact
    24601 aattggtgga gaaactgctg aaatgcctgg aatgtatgga gaagatgact atgatttagc
    24661 aggattttct gtaggaatag cagacaaaga aaagattgtt tctggaaaca atgttaaatc
    24721 aggagatgta ttggttggta tatcttcaag tggagtacac agcaatggat tttcttttat
    24781 aagaaagata tttttagaaa cttacaatta taaaatggaa caatatgttg aagaactagg
    24841 aatgacagtt ggagaagcac ttttaacacc aactaaaata tatgttaaat tagctttaga
    24901 tgtattagct aaacatgaca taaaagctat agctcacata actggtggag ggcttataga
    24961 aaatataaca agagttatac ctaaagggtt aggactagat atcaataaaa aatcttggga
    25021 gaagcctcct atatttaaaa tgatagaagg ttttaatgct gttgatgaga gagaacttca
    25081 taagagtttt aacatgggta ttgggctagt tttaatagta gataaagaaa atgctgatga
    25141 tgttgtaaac tttataaata atagagaaaa tgacaatgct gcttatgtag ataaaaaata
    25201 tagtgaatta ttagaagata aagcttatat aattggtgaa gtagtagata gtcatgaagg
    25261 tgtagaatta tgctaaatat aggagtttta atatctggtg gaggaacaaa tttacaagca
    25321 gttatagatg gtactgagtc tggagaaata aaaggtcagg ttaaagtagt tatctcaagt
    25381 aagcaaggtg cttatgggct agagagagct aaaaatcata acataaaagc aatttgtgaa
    25441 actgatgaag acaagataat agaaattctt aaggaaaata aaatagattt agtagttttg
    25501 gctggttatt taaaaataat cagcccaaag ctggttaacg agtttagaaa caaaatgata
    25561 aacatacatc catcattaat tccttcattt tgtggagctg gattctatgg agaaaaagtt
    25621 catcaaggtg ttatagatta tggagctaaa gtaactggtg ctacagttca ttttgtagat
    25681 gaaggtgctg atactggacc aatcataatg caagatgtag ttaaggtaaa tcaagatgat
    25741 gatgcaaaga cacttgcaaa aagagtgtta gaagttgaac ataggatttt aaaagaaagt
    25801 ataagtcttt tttgtgaaaa taaattaaaa cttcaaggta ggagagtgtt tataaatgag
    25861 taagagagct ttaataagtg taactgacaa gactggtgta gtggaatttg ctaaagagtt
    25921 aaataaatta gattatgaaa ttatatctac aggaaataca tttaaaacat taaaagaaaa
    25981 tggtgttaat gtaatgcaag ttgaagatgt tacaaatttt ccagaaatat tagatggaag
    26041 agtaaaaaca ttaaatccat atatacatgg tggtatactt tataaaagag ataaagaatc
    26101 tcatgtagaa actgtaaatg aacacaaaat acattcaata gatttagtag ctgtaaatct
    26161 atatgatttt gaaggaactt taaaagctgg aaaaagtcat gatgaaataa ttgaaaatat
    26221 agatattggt ggaccatcta tgatacgttc tgctgccaaa aactataagg atgtaatagt
    26281 agtagtagat ataaaagatt atgattctat aatagaaaaa ttaaaaacag atacaatgac
    26341 attagaagac agaaaaaaat tatcatataa agctttctca actacaggaa gatatgatgc
    26401 gttaatatct agttattttg ctggagaagt tggagatacg tatcctgaca tattaaattt
    26461 aactttccaa aaagaacaaa ctttaagata tggagaaaat ccacatcaaa atggtttctt
    26521 atattcacag tcaaatgcaa aaaatccaat cttaaattat gagcaattag gcggtaaaga
    26581 actttctttt aacaacttaa atgatttaca tggatgttta gaagtaatga gagaatttaa
    26641 agatagtgaa gaagtagttt cagtagctat aaaacatgct aattcatgtg gggtaggttt
    26701 aggaaaagat gcttttgaag catatacaaa atgttatgaa gcggataagg tttcaatatt
    26761 tggaggaata gtaggaataa cttctactat agataaagct acagcagaga aattaaatga
    26821 aatattctta gaaatagtag tagcatatga ttttgaacca gaagctttag agatacttaa
    26881 acaaaagaaa aatctaagaa tattaaaatt agctaaaata gaaaatagtt tacaaccata
    26941 tgaaatgaaa tatttagatg gaaaattatt gatacaagat agaaacaata tattagcaga
    27001 aaaaagtgaa aatgtaacaa aggaaaaacc aacagatgca caacttaagg acatggaatt
    27061 tggtatgaga gtagtaaaaa atatgaaatc aaatgcaatt gcagtagtaa aaaatggaca
    27121 aactctagct ttaggttgtg gacaaacatc aagaatttgg gcattaaaaa atgctcttga
    27181 aaataacaaa gataaagatt ttacaggagc tgttttggcg tcagacgcat ttttcccatt
    27241 tgatgattgt gtaacattag ctcatgaata tggaatatca gcagtagttc aaccaggtgg
    27301 ctctataaaa gataaagatt caatagaagc ttgtgacaag tatgatatgg ttatggtatt
    27361 tacaggaata agacacttca aacactaagg aggatattat gaagatattg gttgtaggcg
    27421 gtggcggaag agagcatgct atatgctgga aactaagcaa agaaaaaaat gtagaaaaaa
    27481 tttattgtgc accaggtaat gcaggaattg caaacgtagc agaatgtgta aatataggtg
    27541 atactaatat agaagaactt ttaaaatttg ccaaagaaaa tgaaataggt ctgacaatag
    27601 taggaccaga agtaccacta gttatgggaa tagtagatga gtttgaaaaa gaaggattaa
    27661 gagtatttgg acctaataaa aaatgtgctc aacttgaagg aagtaaagct ttttcaaaag
    27721 aatttatgat aaaacataac atacctactg caaaatataa agaatataca aacttagaag
    27781 aagctatatc agaaatagat agttttggat atccagtagt aataaaagcg gacggattag
    27841 ctgctggaaa aggtgttgta atacctgaaa atagagaaga tgctatagca actttaaaag
    27901 aaatgatgtc agataagaag tttggagctg ctggagataa aatagtaatt gaagagtttt
    27961 taaaaggaat agaaacttca attctagcat ttgtagacaa tgatacaata gttcctatgg
    28021 caagtgcaaa agaccataaa aaagtaaaca actatgagca aggtccaaac actggaggaa
    28081 tgggaacttt ttcacctagt gaaatatata cagaagaatt agcaaataaa gtaaaagaga
    28141 cagtattaga aaaaacttta gaaggtttca aaaaagatgg acttaatttt aaaggtattt
    28201 tatttgttgg tcttatgata actgaagatg gagaaaaagt acttgaatat aatgtaagat
    28261 ttggagaccc tgagacacaa tctgttttat ttagattaga aacagattta catgagataa
    28321 tggaagctat actagataat aagttaaaag atatagaaat aaactatagt gatgatgaag
    28381 ctgtatgtgt tatgcttaca tcaggagggt atccagacag ttatgaaaaa gggaaaatta
    28441 taactggtct tgaaaacttg gatgatgata tagtagtatt ccatagtggc actaagatgt
    28501 ttgatggtaa tttggttacc aatggaggaa gagtaattgg tataactgca aagtcaacta
    28561 gagttaagga tgcagcagaa aaagtttatg aaaacataaa gaagataaac tttgaaggaa
    28621 tgcactatag aacagacata ggaagataat ttttctaaaa tggaggataa ggtatgttga
    28681 atactgaaaa taaagactca atggttagaa gagtattggt tgaaaaaaga gaaggttttg
    28741 accttgaggc taaagcttta aaaaaagact tagtagaaag tttacacata gataatatag
    28801 aaaatttaag aatattaaat agatatgatg tagaaggaat atcagaagaa gtttatgaaa
    28861 atgcagcaaa gacaatattc tctgaaccaa atttagatgt agtatattat gaagaaatac
    28921 caaaattaaa tgatgaaaga gtatttgcaa tagaatttct tcctggtcaa tacgaccaaa
    28981 gaggtgattg ggcagctcaa tgtgtacaaa ttgtaaatca agggataaga cctgctatta
    29041 atacagcaaa agtttatata ttatcaggca aaataactga tgaagagttt tctaaaataa
    29101 aagattactg tataaatcca gtagatagta gagaagcatc tttagagaaa ccagaaacgt
    29161 taaaaatgga aactgaaata ccaacaacag ttgaagtatt agatggattt atagatttag
    29221 atgaaaatgg attaagaaca tttgtaagtg aaaaaggatt agcaatgact ttaggagact
    29281 tacaacacgt tcaaaaatac tttaaagata cagaaaagag aaatccaact ataacagaaa
    29341 taaaagtatt agatacttat tggtctgatc attgtagaca tactactttt atgactgaaa
    29401 tagaaaatgt aaagatagaa gatggtaagt ttaatgatat agtaaaagaa gcgtatcaaa
    29461 tgtatcttaa ctcaagagac aatgtatatg tgaacagaca taaagatata tgtttaatgg
    29521 atatagccac tgttgcagta aaagaattaa agaaaaatgg gaaattaaat gacctagatg
    29581 aaagtgaaga aataaatgca tgtagtataa acgtagatgt tgaagttgat ggtaagatgg
    29641 aaaaatatct agtaatgttt aaaaatgaaa ctcacaacca tccaactgaa atagaaccat
    29701 ttggtggagc agctacttgt ttaggaggag ctataagaga cccattatca ggaagaagtt
    29761 atgtttatca agcaatgcgt gttacaggaa gtgctgaccc aagaacgact ttagaagata
    29821 ctttacctgg aaaacttatg caaagaaaaa taactacaga agctgctcat ggatatagtt
    29881 catatggtaa ccaaataggt cttacaactg gacaagttgc agaagtatat gatgaaaact
    29941 ttgttgcaaa gagaatggaa ataggtgcag ttatagcagc agcaccaaaa gagaatgtag
    30001 taagagaaag acctgaagca ggagatgtaa tcgttcttct tggaggaaaa acaggaagag
    30061 atggctgtgg aggagcaact ggttcatcta aagaacatag tgaagagtca atcttaactt
    30121 gtagtgcaga agttcaaaaa ggagatgctc ctaacgaaag aaaaatacaa agattcttta
    30181 gaaataaaga agttgctcaa atgataaaaa gatgtaatga ttttggagca ggtggagttt
    30241 gtgttgctat aggagagatt gctgatagct tagatataaa cttagactta gttcctaaaa
    30301 aatatgatgg acttgatgga actgagcttg caatttcaga gtcacaagag cgtatggcag
    30361 tagccataaa aaaagaaaat aaagataaat ttatacaatt agcagtagaa gaaaacttag
    30421 aagctacgca tgtagctaca gtaacagata caggatattt aagaatgttc tggaatggaa
    30481 aagcaattgt agatataaat agagagtttt tagatacaaa cggagtaaaa caaactactg
    30541 atgttcatgt tactaaagta gatgaagaaa atacattctt tagctctaat gaaatagtaa
    30601 aagatgttaa gtgtgcaagt atgaaagaca agtttacaaa agtactatct gaccttaatg
    30661 tttgttctca aaaaggatta gtagagatgt ttgataatac aattggtggt aatacagtac
    30721 ttatgccatt tggaggaaag tatcaagcga ctccaacaca aggtatggtt gctaagatac
    30781 cagtacttgg aggagaaact aatacttcta caataatgac ttatggatac aatccaaagg
    30841 taggaaaatg gagcccattc catggtgcct tgtatgcagt agtagaatct gtgtgtaaat
    30901 tggttgctat tggaggaaat tatagtacaa caagacttac attccaagag tattttgaaa
    30961 aacttggtaa caatccagaa aaatggggta aaccattctc agcactttta ggagcgtttt
    31021 atgcacaaag taaatttgag atacctgcta taggtggaaa agacagtatg tctggtacat
    31081 ttaaagatat tgaagttcca ccaacattag tttcatttgc tgttgacaca gtagatgcga
    31141 agaaagtagt atctccagaa tttaaaaaag cagactcaaa agtagtaatg ttatgtgtaa
    31201 acaaggcaga aaatgatgtt gtagattttg aggaattaaa gagaaactta gataaagtaa
    31261 gagaacttat acatggaaat aaagttttat caacatatgc attaggattt gcaggtgtag
    31321 gtgaagcaat aagtaaaatg gcttttggta ataaaatagg atttaagttt agtgaagaag
    31381 ctgaaaaagc atttacagat aataaattat ttgaggctag ttatggaaat atagtacttg
    31441 aattagcaaa tgatgattta agtatgttag aaggatacaa ttatgttgtg attggaagta
    31501 cagttaaaga agctagtata tttatcaaag gtgaagaact tgcattagat gaattatata
    31561 aagcacattg tagtacttta gagcctatat tcccaactaa aacagaagaa gtaaaatcaa
    31621 agatagaaac tataagttat atatcacaag gagaagctaa aaaatcatca ttaagtatag
    31681 ctactccaag agtatttata ccagcattcc ctggaacaaa ctgtgaatat gactctgcaa
    31741 gagcatttga aagagcagga gctaatgcaa gtataagagt atttaagaat ttaacttata
    31801 aagacataga agattctata gatacaatag taaacgaaat aaaatcttct caaataataa
    31861 tgttaccagg tggatttagt gctggtgatg agccagatgg ttctggtaaa tttatagcta
    31921 ctgtatttag aaatcctaga gtgcaagaag ctataaatga atttttaact caaaaagatg
    31981 gactaatgtt aggtatctgt aatggattcc aagtattaat taaattaggg ttagttccat
    32041 atggagaaat aagagttcca agtgaaagtg ctccaacact tacttacaat aatattggtc
    32101 gccatcaagc taagattgct agaactagaa tttcatctaa taaatctcct tggttagctc
    32161 aaactaatgt tggagatatt cataatatag caatttctca tggagaaggt aagtttgttg
    32221 ccagtgaaga tgttatgaga gaattaattg ctaatggaca agtagcaact caatatgttg
    32281 actttaataa tgaagctact tatgatattg agtttaatcc aaatggttca ttctatgctg
    32341 ttgaaggtat aactagtgct gatggtagag tgtttggtaa aatgggacat tctgaaagaa
    32401 ttggtgagga agtatataag aatattatag gtgaaaaaga ccaaaagata tttgaatctg
    32461 gagttaaata ttttagataa agctttgatg tttaattgat agctagaata tataatttag
    32521 atatttagat ttaaagagat gtaataatat gatgataatc atttaatatt acatctcttt
    32581 tttatttatc taagaaataa taagttcaac ctaagttaaa atacaagctg tgttataatt
    32641 aattattaag taaaattgaa tatttattgg agggcaacat aattaatgaa aatattaata
    32701 acagggtcta atggtcaatt aggaaaagaa ttggttaacc aattagaagc aatcaatcaa
    32761 agtataaacc aaccaaaata tgttatatta gctacaacaa gaagtgattt ggacatatcc
    32821 aatcagacta atgtagataa ttttattttg cataataaac ctgatgtagt tgtaaactgt
    32881 gcagcatata caaaggttga tgcatgtgaa gataatatcg aaattgcata caaaataaat
    32941 gctttaggag tgagaaatct agcaatagca tcagaaaaag ttaatgctaa gcttattcac
    33001 atatcaactg actatgtatt caatggtttt tctaaatatc catataggga agacaataaa
    33061 actgaaccca attctgtata tggaaaaagt aaacttatgg gagaaaaatt tgttgaacaa
    33121 ttctcacata agtactttat attgagaaca gcatggttat atggtaatgg gaataatttt
    33181 gtaaagacca tgataaaact ttctttagaa aataaagagg ttaatgtggt taatgaccag
    33241 tttggaactc caacaagtac agtagactta gcaaaaatta taataagaat catggaaaca
    33301 gaacattatg gagtttatca tgctacatgt gaaggtgagt gtagttggta tgattttgcc
    33361 aaaaagatat ttaaactaaa aaatatagat ataaaagtaa atccaattaa gagtaacgaa
    33421 tttaaatgta aggctccaag accactatat tctgtattgg ataattttat gttgaagtta
    33481 attggtttaa attcttttag aaagtgggaa gaatccattg aagaatattt agaaagatat
    33541 gatataaatg aaaagtaaat gtattatttt gagaaaagaa aataagatat tataaaaaat
    33601 ataaatattt cttttattta tccgataatc ataatatgac aaaaacaaat ttaaggatgg
    33661 aaaaagatga aaggaattat tttagcagga gggtctggta caagactata tcctataaca
    33721 aaatgtatat caaaacaaac acttccaata tacgataaac caatgatata ttaccctatg
    33781 tcggttctta tgttggcagg gatacaagat atattaataa tatctacacc aagagatata
    33841 aaagcatttg aagaattatt tggagatgga agttcactag ggcttaacat aacatatgca
    33901 attcaggaga aagcaaatgg aattgcagaa gcgtttataa taggagaaga atttatagga
    33961 aatgacagag tgtctcttgt attaggggat aatatatttt atggatatgg atttagtgaa
    34021 aggttggaga atgcagttaa aagaaaagga gcaactatat ttgggtatca tgtaagtaat
    34081 ccaaattcgt ttggagttgt agaatttgat aaggatttta atgtattgtc aatagaagaa
    34141 aaacctacag ttcctaaatc taattatgct ataccaggat tatattttta tgataatgat
    34201 gttgtagaga tagcaaagct agttgaaccg tcagatagag gtgaattaga aataacctct
    34261 ataaacagtg aatatctaaa acgaggaaaa ctaaaagtgg aacttctagg aagaggtatg
    34321 gcttggcttg atactggtac acataaaggt ctattggatg cttctaatta tgttgaagtg
    34381 gttcaaacaa gacagggact gtatatagca tgtttagaag agattgcata tacaaaagga
    34441 tatataagta gagaacaatt aatgaaacta gccaagccac tgataaaaac tgaatatggt
    34501 caatatctat taaaattggc tagtgaagat atgtaatatg gtagataaaa tttattataa
    34561 attttattaa gggagtttat tataatggga aaaatcaatg ttataaagac taaaatagaa
    34621 ggattatata tagtcgaacc aaatgtattt tatgatgaaa gaggatattt tatggaaagc
    34681 tataataaaa aggattttat agagcagggt cttgatatgt gttttattca agataatgag
    34741 tctagctcaa gaaaaggcgt tttaagagga atgcattttc aggttaaata tcctcaagga
    34801 aaattagtca gagttacaga gggagaagtt ttcgatgttg cagttgattt aaggaaagat
    34861 tcacaaacat ttgggaaatg ggaaggtgta atattgtctg ataagaataa aaaacaattt
    34921 tatattccag aagggtttgc acatggattt ttagttttat cagaaaaagc agtatttagt
    34981 tacaaatgta caaattatta ttacccagaa tttgagaatg gctttatatg gaatgacaag
    35041 caaatatcta ttgagtggcc tttaaaagga attgaagaaa tatttttatc agaaaaggac
    35101 aaaaaacaaa aaagttttaa agatatttgt acaagacgtt aataaaaatt tattagaatt
    35161 aacatttagg agaaaaaata tgaaaaaaat actgataact ggaggagcag gatttattgg
    35221 gagtaatttt atacattata tgcttaacaa gtatgtagat tattttattg ttaacctaga
    35281 cttgttgact tatgctggta atttagagac attaatagaa atacaagaca attccaatta
    35341 taaatttgtt aaaggagata tttcaaatag ggagcaggtg tataagctat ttgaagaaga
    35401 aaggtttgat atagttgtta actttgccgc tgaatctcat gtagataggt cagttgagaa
    35461 tcctgattta tttattaaaa caaacattat aggaacacaa gtacttttag atgcatctat
    35521 aaaatatgga gttaaaaggt atcatcaaat atctacagac gaagtgtatg gtgatttacc
    35581 aattgataga aaggatttat tctttacaga acaatcttct atcaatccaa gttctccata
    35641 ttcagcttct aaagcatcag cagatttatt ggtaagttct tattatagaa catatggatt
    35701 gttaacaact atatctaggt gttccaacaa ttatgggcca tatcattttc ctgaaaaatt
    35761 gattcctctt atgattttaa atgctttgga aaacaaacaa ttgccagtat atgggaatgg
    35821 ggaaaatgta agagattggt tacatgtata tgaccattgt actgctatag acttaataat
    35881 acataaagga aatatagggg agatttacaa tataggaggt cataatgaaa gaagtaatct
    35941 agaagtagta aaaatgatat taaatctttt aggtaaatct gaagagttaa tatcctatgt
    36001 aaatgataga cctggtcatg atttaagata tgctattgat gcaactaaaa tagagaatga
    36061 gttaggttgg aaggcaaaat atgactttga tttgggtata aaagaaactg ttaagtggta
    36121 tatagaaaat gaatcttggt ggaaagctgt tttatcagta taactttaaa atttagaaag
    36181 gggcgtttta tattgaatga gataagttca ctaattaata tattagcatt gactcaatta
    36241 tctggtagta atactacaaa tcaatgtaat tgtacatata ataattcatc tggatttgat
    36301 atgattatga tgaccttgtt aaaagcatta tcacaaaata atcaacatac ttctaatagc
    36361 tacaatttat tgtctaattc tgagaattta tttaatgaac ttgataatgt agtaaataat
    36421 accactagta gatttataga tgttgataca aaagataaaa atgtaaagtt gagaattgaa
    36481 aatgctgtag atcaagcatc aaaaaaatat aacgtagatt caaatcttat aaaagcaata
    36541 attaaagttg aatcagattt taatccaaat accgtttctt ctgctggtgc taagggtctt
    36601 atgcaactta tgccagaaaa ctgcagagac ttaggagtta cagacccttt taatatagaa
    36661 cagaatatag atgctggaac tagacatatt aaggaataca ttgatatgtt tggagggagc
    36721 atagaaatgg gattgatggc atataatggt ggtcctggaa gaatgaaaag tagaggagta
    36781 gaatcaatct ctgacctgta taaaatgcca aaagaaacac aaaattatat tcctaaggtt
    36841 atgaaatatt atagagggta ggctttatta tgggaataaa tatagataag ctaaacataa
    36901 gtccaagtat aaatatggag gttaaaaaac taaaagagag taataaattt tctgacaaat
    36961 taaactcttt aaaacaatct tcttcattgg aagatataaa acgaaatttg gaaagtgtaa
    37021 aaaaggcagg agaaaggctt gtacttactc aaaactatgg cgatattagt atatataaaa
    37081 atgcagtaaa agaataccta aaatctgttg tagataatat gtattcactt gataaaaata
    37141 gtagcttttg ggagcatcag tattataaga atgtaaagat tgttgatagt aaacttgagg
    37201 atatgactag taagttaatt agtgaagaaa aagaaaacat agatattgtt tctactgttg
    37261 acatgataca aggcttattg atagatatgt atagataagg ttatacaagg agaaaaattt
    37321 tatgaatagc aaaaaagagg atatatatga attgaatttt gggcaattaa tagaagaaaa
    37381 atctggtgtt atagaagaaa atcaaaatgt ttttaatgca aaagtaaatg tagctgtttc
    37441 tataggaaat acaacagaaa caataaaaaa tatattagat ttaaaagaag gctctataat
    37501 aaaattaagt aagaatgtgg atgaaaaatt agatatatat gcaaacgata gattgtttgc
    37561 ttatggagaa agcattatta caaatgagag gttatctgta agattatcta aaatagaaga
    37621 tccagatgta aattagcatt ttaaatagta tccctttagg ctattctgta tgagtttagc
    37681 taaggggata tttttataaa aaatttaaaa tatgtgtgaa ttatataaat atttttattt
    37741 tatgagcgat aactaaatta taagtatgta attttggagg tgaaactatg gatattaaaa
    37801 atgtaagttc aaatattgta gtgaataatt atttaaagaa tacatctggt ataaaaaaag
    37861 tggaagaggt taaaaaaatt aataaaacag ataagataga gttatctaaa tttgcaaagg
    37921 aaatggcaag tgtgtcaaat atgagtgatg agaatattag aaataaaaaa gtcgatgaaa
    37981 taaaaaatgc attagaaaat ggaacttaca aaataaaacc aaaagaaatt gcgaaaaaaa
    38041 tgatagagga tatgcgagga taaagtcatg attacagact taaaagttat aatatatgaa
    38101 gaaaaaaata taattagtaa gatgatggaa ttattaaaag aacaatttga ttatatagtt
    38161 gaaaaagact tagaaaattt aaatatgtta aatcctaaac tagaagatat tagcagggag
    38221 cttgcatcca tagaaataaa gagaagacaa ctttttggtg atgatatttc aatgagtgaa
    38281 gttgttgaaa atagtaatga tggatactta aaagaaatat atacagactt gaaacacatt
    38341 cttgctttag ctaaaaatca acaagaatca aatgattctc taataaagaa agaacttatt
    38401 tttacgaaaa aaatgattaa tttcataaaa ccagctgata agcaaactac aacttataat
    38461 tcttatggaa atattagaaa ataaatatta ggaggagaaa tatggcagga ttattttcca
    38521 ttttaaatac agctaattca ggaatgaatg cgcaccaaaa agcaatacag acaatttctc
    38581 ataatataag taatctagat acagacggtt attctaggca aaggaccgag tttgccacaa
    38641 atagtccaat gtatatgcct agtttgagta attcaattgc aagaggacaa ttagggactg
    38701 gagtacatgt aacggatgta acaagagcta gaaatagttt ttatgattac caatttaggg
    38761 cagaagctca taagtatggt aagacagttt caaaatatga ttattacaat actatagaaa
    38821 ctatactaaa tgaaccatca gactatggaa tatctgcagg tatagatgat ttttttaaag
    38881 gatgggagtc attatcaaag gatataaata gtgacagtaa aaaaagtcta gtggtagaaa
    38941 acgcatctaa tttagcaact ttaataagtg aaagttataa gaagcttgat aagttaaaag
    39001 aagatataga ttctaatata gacactgaga taaaacaaat aaatgacatg ttaaaaagtc
    39061 ttgaagattt aaataaatct attgatatta tatctggttc tggctctaca ccaaatgatt
    39121 tacttgatga aagagataga attttagata acttgagttt taaactagac tttgaaaata
    39181 gtgatgttaa aaatatgctt gcagatggta aattagaact taatgaatta aaaaatccag
    39241 atggaacttg gaaaacaggt atatcaggga ccttacaagg cttgtttgaa atgcatggta
    39301 agattgatac atataaaagc gatttaaaag atgtatctga tggattagct aaacagataa
    39361 atgatgttta taatacgtct gcaggaataa cagtaacaga tttttttata acttcaaatg
    39421 tagatggtga agatattata aagataaatc cagctataaa gagtaaccca aatgaattaa
    39481 agcttactgc tgatgaagct tcaaaaattg ctaagttaaa ggatgaaaaa atagatattg
    39541 gggtggctgg tggaaaagta agtacaataa gtgaccacta taaagccttt gcagaatcaa
    39601 tcggtttaga ttctcaaaaa gtaaatcaag atgaagcaaa tcaacgtaaa attataaata
    39661 atattgataa ctcaagaatg agtgtttcag gtgtatcttt ggatgaagaa atgacagagc
    39721 ttataaaaat acaacgttca tatcaagcta gtgcaaaagt tatgtcaaca gctgtgcaac
    39781 tactggatgt tgtaataaat ggaataattt aatagaaggg ggaatttata atgagagtca
    39841 gtacaggtat gatgtctagc agctatctaa actcactaca agataatcta caaagattgg
    39901 ataaggttaa tagacaagtt aatacaacaa aagaaataaa caagctatca gataatccat
    39961 ataaagcaat aaagatatta aactcaaaaa gtgaaataaa gactatggag acttatgttg
    40021 agaattgtaa agatacaggg aattggttag aaactactga tactgcatta gatcagcttg
    40081 gaaaattatt atcagacata aagaaaactt tggtggcaag tggtgatggt gcatactcag
    40141 atgatgaatt aaagactctt agtaatgaaa ctaatgaaaa aatgaaagaa attgcaaatg
    40201 ctttaaatgc aacacatgaa gggaagtaca tattttcagg ttcaaatacg ggggtaccac
    40261 ctgttgaatg tatagataat gctgatggtt cagtgagttt aaagtttaat tctagtctaa
    40321 atcttaataa attaaatgac tctttgagta tggatatagc tcaaggaata agtgtagatt
    40381 ataacgttaa attgagtagc cttggatttg acccaacaaa aactgaccca tttgaagagt
    40441 taaataacat atcaaaaaaa ttagcaaatc cagatgctga tgctataaaa gagcttacaa
    40501 caacttgttt gggcgatatg gaacaactaa tagaaaatac agtaaatgtt aggtctatat
    40561 atgggacaaa agcaaataca gtagaggcta tgaaggaaaa aaacgatgat agtttgatac
    40621 agttaaagga tattttgtca caaaatgaag aaatagatta tggtgaaaaa cttgttcaat
    40681 taaaggcagc agagttaact tatcaagctt cactacaaac aggaggaaag ttatttaatg
    40741 tatctatatt agattacata taataaaata acgcagatat gatgaaggtt acattaaaaa
    40801 aaggtatatt aggttttgaa aatttaaaag aatatgagct tttagatata gaagataatg
    40861 attatttaaa agaatttaat tctactgaag aagaaggtat aggatttgtt gttgtatctc
    40921 catttgagat tatcaatgaa tatgaaatag ttttaaatca ggaaacaata gaaaaactag
    40981 aagtgaaatc tccaaaggat gttgtattat ttaatataat tactcttggt cagacatttg
    41041 aagaatcaac tgtgaacatg aaagctccta tagtgataaa tataaaaact aattttggaa
    41101 tgcaaataat tttacaggat gataaatatt caataaggca tccattattg agaggtgata
    41161 gtggatgcta gtaatttcaa gaaaaaaaga tgaagcagta cttataggag aaagcataga
    41221 agtaaaaatt gtaggggtag atggaaacaa tgtgaaacta gctatatcag cgcctaacaa
    41281 tataagtata ttaagaaaag aaatatacga aaaagtaaag agtgagaata taaaagctac
    41341 aaataaaaat ataaaaattt taaagtcatt aaaataataa gcttggagga agtaatatat
    41401 gtatggagaa aatccttata attcttataa acaaaatgct gtttttatgg catcaaagga
    41461 acaattgtta cttatgcttg ttgatggagc agtaaaatat accaaaatag ccaaaacagc
    41521 tatcttagat aaaaatacac aaaaagcgca tagagagctt ataagagttc aggatatatt
    41581 tacagaacta atggttacat tagaccaaaa tgcaggtcaa tgggcaaagg atatgtacag
    41641 agtttatgat tttgtaagat atgaactttc aagagctaat attagaaaag acattcaaat
    41701 aatagataat gtgttgcctg taatagaaca aattaaagat acttggcatg aagctgataa
    41761 aaaaagtaaa gaagaaagaa gtaggtacaa ataatggaat taaatttagc tgaattagat
    41821 aagttatcaa aagaggaatt actattgatg cttgtagatg gaacagtaaa atataccaat
    41881 atatccaaag aagctctttt aaataacgac tatttgaaag cacataatga acttgtaaga
    41941 gttcaaaata tatttacaga actaatgact acattagacc aagatgcagg tcaatgggca
    42001 aaggatatgt ataaagttta tgaatttata aaatctgaat tagcaatagc tgatgaaaat
    42061 aaagatatta aaataattga tgatatattg ccaatagtaa aacaaattag agatacatgg
    42121 catgaagttt acaatcaact aaaaatataa ttggatggag ggataaaggt atgtcaagta
    42181 taagtcctat aagagttaca ggtctttcag gaaattttga tatggaaggc ataatcgaag
    42241 ctagtatgat tagagacaag gaaaaagttg ataaagcaaa acaagaacaa caaatcgtta
    42301 aatggaagca agaaatatat agaaatgtta tacaagaatc aaaagatctt tatgataaat
    42361 atctaagcgt aaattctcct aatagtatag taagtgaaaa agcatactct tctacaagaa
    42421 taaccagttc tgatgaaagt attatagtag caaaaggctc agctggtgca gaaaaaataa
    42481 attatcaatt tgcagtttct caaatggctg aaccagcaaa atttactatt aaattaaatt
    42541 caagtgaacc tattgttcaa cagtttcctc caaatgctag tggagcgagt tctttaacta
    42601 taggagatgt aaatatacca atatctgaac aagatactac aagtactatt gtaagtaaga
    42661 taaactccct ttgcgcagat aatgatataa aggcttctta tagtgagatg acaggtgaat
    42721 tgattatttc aagaaaacag actggttcgt catcagacat taatttaaga gtaattggaa
    42781 atgacaattt agctcagcaa attgctaatg ataatggtat cacatttata aatgatgctg
    42841 gtggaaacaa agtggcaaat gtatatggaa agaatctaga agctgatgta actgatgaac
    42901 atggaagagt aactcatata agtaaagaac aaaattcatt taatatagat aatattgact
    42961 ataatgtaaa ttcaaaagga actgcaaagt tgacttctgt cactgatact gaagaagctg
    43021 ttaaaaatat gcaagcattt gtggatgatt ataataaact gatggacaag gtctatggtt
    43081 tagttactac taaaaaacca aaagattatc cgcctcttac agatgcccaa aaagaagata
    43141 tgacaactga agaaatagaa aaatgggaaa agaaagctaa agaaggtata cttagaaatg
    43201 atgatgagtt aagaggtttt gttgaagata ttcaatctgc attttttgga gatggaaaaa
    43261 atattattgc attaagaaaa ctaggtatca atgaaagtga aaattacaat aaaaaaggtc
    43321 aaatatcatt taatgcagat actttttcaa aggctcttat agatgatagt gataaggtat
    43381 acaaaacact agcaggttat tcttcgaatt atgatgataa gggaatgttt gaaaagctaa
    43441 aagatattgt atatgaatat tctggaagtt caacttctaa acttcctaaa aaagcaggta
    43501 tagaaaaaac tgcttctgct agtgaaaatg tatattcaaa acaaattgca gagcaagaaa
    43561 gaaatataag caggttagtt gaaaaaatga atgataaaga gaaaagactt tatgctaaat
    43621 attcagcctt agaatctttg ttgaatcagt attcttccca aatgaattat ttctcacaag
    43681 cacagggtaa ttaattatgg ataaattaaa agaaaaatta aatttatata aagatatatc
    43741 tttacaaatt ataaatttga ttgaaaagga agaatatata aagataagta ttaagttagg
    43801 tgaaagacaa gagattataa atagtgtaag tgaaattgat agaaatgatt ttatacagct
    43861 ttataataga atggaattaa ttgaaattga tagcaggata agagatattt tacaaggaca
    43921 attattagaa gtaaaaaaag aattacatga gtataagctt actaaacaag tgaacacaat
    43981 gtattataac ttaaatagag aaaaagtaaa tatttttaat aaaaaagtat aaagttatgt
    44041 accatcttgt ccgattatat aaatgaagaa ttaataaaaa agattaaaag tagaaatgac
    44101 aaggatgtca actatactaa ggagggtaaa ataatgagag ttaatacaaa tgtaagtgct
    44161 ttgatagcaa ataaccaaat gggaagaaac gtaaatgcac aaagtaagtc tatggagaag
    44221 ctatcttctg gtgttagaat taagagagct gctgacgatg ctgctgggct tgctatatct
    44281 gagaaaatga gagctcaaat aaaaggttta gaccaagcag gaagaaacgt tcaagatggt
    44341 atatctgttg tacaaacagc agaaggtgca ttagaagaaa ctggtaacat actacaaaga
    44401 atgagaactt tatcagtaca atcttcaaat gaaactaata ctgctgaaga aagacaaaag
    44461 atagctgatg agttactaca attaaaagat gaagttgaaa gaatatcaag ctcaattgag
    44521 tttaatggta agaaattact tgatggaagt tctacagaaa taagattaca agttggagca
    44581 aactttggaa caaatgttgc aggaacatct aacaacaaca atgaaataaa agttgctcta
    44641 gtaaatactt caagtataat gagtaaagca ggtataacaa gttctacaat agcaagctta
    44701 aatgcagatg gaacttctgg aacaaatgca gctaaacaaa tggtatctag cttagatgta
    44761 gctcttaaag aattaaatac atcaagagca aaattagggg cacaacaaaa tagactagaa
    44821 tcaactcaaa acaacttaaa taatactata gaaaatgtta cagcagctga atcaagaata
    44881 agagatacag atgttgcttc agaaatggtt aacttatcta aaatgaatat attagttcaa
    44941 gcatcacagt caatgcttgc tcaagctaat caacaaccac aaggagtttt acaattatta
    45001 ggataaaata attttgtata ttggatatag aagaaagggt aaggctttgc tttactcctt
    45061 tcttttttta caaatatact tttgaaagga aaatttatat gttacttagt atagttatga
    45121 ttgttaaaaa tgaagaaaaa atacttgaaa aaactttaaa atcattaacc acattaagaa
    45181 attctataga aagtgaactt ataatagtcg atacaggttc tacagatgat actataaaaa
    45241 tatctaagaa gtacacggaa aaagtgtatt ttcataattg gaataatgat ttttctagta
    45301 tgagaaatat atcaatatcc tatgctaaag gtgaatggtt acttatatta gatgcagatg
    45361 aaatactaat tgattcttca actattgtaa aattttttaa agatggtctt gataaaaaat
    45421 ttaattctgc ttcaatacaa ttaaaaaatc tttactcata tgataaaaaa ttatatggat
    45481 attgttcagt gcttagactt tttaaaaacg ttgattttag ataccatggt aaagtacatg
    45541 aacaaccaat atacaaaaac cctatattta ataatgttgc tgattttgaa cattatggat
    45601 atttgtttga agatgaagaa ataagattaa ataaggtgaa aagaaatgaa aaactattat
    45661 ttcaagagtt aaaagagaat gataattctc catatacaaa ctatcaatta gggaaaaatt
    45721 ttattatatt aggaaaatat caggaggctt tatactatct tgagaaatct tatgaattat
    45781 attctaaact agaattggca cctggttact tgataacaag ccttgtaaaa acatatttat
    45841 atttaggaaa acataagaag tgtgaaagat tgtgcttaaa gtatattaag aaagacatga
    45901 ataatattga tatatattat tatattgcac aagcacaagt agatttagga aagtatgaaa
    45961 atagtataga ttcgtataag agatatattt acttgttaga taattatgaa ataagtacac
    46021 aagcaaatag tttattttca gacactgata ctgtagggct tagagatgag gctattatta
    46081 cactgataaa gatttattat aagcttgaaa aatatgagtt tgtaatttca gagtataata
    46141 acattgaaga tgtggaaaag aaaaagaatg tgtactttag cttatttatg tcactatata
    46201 aattgaatag atttgaagat ataaaaaatt attataaaga agtttcaaat tctaaaattg
    46261 aaaaaaatag tttttataga aatatagaag aagttataaa taatattaaa gaggatgaaa
    46321 aagagtatgt atataaaatc ctttgtgaca ttgaaggtaa ttatggcatt ttaaatcaaa
    46381 taaggataaa taaatgtgta tctatagata aatgtaaaga aatactcaat gaagaaaagg
    46441 aaataattta tgcatatatt ataaaaatag cttttgaaga gaagattgat ttactagata
    46501 ttttttatga aatggaatat gtatggatag agaaatatct aaaatatctt ttagcattag
    46561 aaagaagttt taatttagta ctatataagt acataattag tcgtccaaat acatcagata
    46621 tggaaaagat aagagtatat aaagctatat ctaaagtagt tttagaaagt ataagcttaa
    46681 gtgatgaaaa atataaggag attttttatc tttatataat gtattcttat aagtacataa
    46741 gatacatata tagcaattta agtgattttg aattaataaa atttgtttgt aatgatttag
    46801 ataagttcac tatagaattt aagcatctac ttgatattaa aaataaagta aataatgcta
    46861 atgaaaaatt agagtatata catagtatga ggaaattact aaatgagtat cctttttata
    46921 ataaaataat aaaaatactt ataggtgaat tagaagaaaa tataaaagaa agtgaagaat
    46981 ttaaggattt aaaagatagt tttattatta gtatagaaaa tatgattgaa actggcaaaa
    47041 taaatgatgc gaaattattg gtagatgact attcaaaaac atttgtggat gatataaaga
    47101 ttttaaatat aaagggaatt ttatacatgt ttgaaaataa gcttgataaa gctgatttta
    47161 tgttaaaaaa ggcattatca ttagatgtag aaaatgaaga tactatatat aatatagaat
    47221 acttaaaaag tttaagataa gtcaaaaata ggagaattga agaatgaata taccaatagt
    47281 ggttaatgaa aaatctaaag acataataaa agattggcaa tatacatgta caaatgaaga
    47341 tataaaattt acaagcataa taatattgac atataatcaa atagaatata ctaaattatg
    47401 tattgaaagt attaggaaat ttaccccaaa gaataaatat gaaataataa taattgataa
    47461 taactcttct gatggaacag ttgagtggtt aaagggacaa tctgatataa aatctgtgta
    47521 taataacaaa aacttaggat ttccaaaagg atgcaatcaa ggtattgagt tagctactgg
    47581 tgaaaacata ttgttgttaa ataatgatgt aatagttact ccaaattggc tctataattt
    47641 gaataaagct ttatggtctc aagataatat aggtgctgta ggacctatta cgaatgcatg
    47701 ttcatattat cagcaaattg atgttgatta taagtcaatt gaggacatgt ttatatttgc
    47761 acacaaaata aataaatcta atattaacct atggaaatat agattgaagt tagttggatt
    47821 ttgcatgtta ataaaaaaaa ctgttctgga taatgtaggg gttttagatg aattattcac
    47881 acctggaaat tttgaagatg atgatttatc ttttaggatg atagagtcag gatataagtt
    47941 attattatgc caggatactt ttatacacca ttttggaagt gtgtctttta aagaaaatcg
    48001 taataaatat acagatataa tgtatattaa tagaagaaaa tttgaaacta agtggggatt
    48061 taatccagaa tatagtggaa tgataagaac agatttgatt tctaaaatag atgatagttt
    48121 ggaggcaaat attaatgttt tagaaatagg atgcggtata ggggctactc ttttagaaat
    48181 aaaaaatata tataaaaatg catcaatata tggaatagaa attagtgagt cagcaggtaa
    48241 acttgcaaag tatagtgcag atgtacttat agcaaatata gaaaaagtaa aattggatta
    48301 taaaaaagat ttttttgatt atataatatt gggagatgta cttgaacatt tgattgaccc
    48361 atggaagata gtcaatgaat tgaaacaata tctaaagaag gatggttatc tggtatctag
    48421 tataccaaat attatgcatg tttctgtttt aagaaatctt gtgttaggta attttacata
    48481 tgaagattca ggaattttgg acaagactca tttaaggttt tttacattaa atgagataac
    48541 aaaaatgttt aatgatagta attacataat taatagtatt acagctacta gtatgccact
    48601 ttcggaaatt gataatagct tcattgatac aatatgtaag gaaagctgta aagaaatgag
    48661 acaacagtac gaatcttatc aatatatagt aaaagcctct aaaatcctag atactaaaag
    48721 atattctagt attagtatga ttaatttaaa atacgcttta atgagaattg ataatgaatt
    48781 agatgtagat agtaatttaa gttatatatt tgataattat aatataactg aaccatgttt
    48841 tgttgatgat attgaatatc taattgatac atttgtgata aataaagcaa ctctattaaa
    48901 tagattagga gttgaggcat ttaacagagg tctaggagat tttagtataa acatgtttat
    48961 gacagtatta gagatggata gagatgatat tgactcaata tataatataa caagtgtatt
    49021 atgtgaatta gaagaatttg atactgctta taatttaatt aaaaatagta gcgaaaaagt
    49081 acagagtgaa agtgatatac aagagatact ttgttttatt gaggggaaga aatatgaata
    49141 atgataagat atgttttata acctgtgtaa atgatgaaag gctttatgaa gaatgtcttg
    49201 tatatataaa tagcctagac attcctaaaa actttagtat agaaacagta gctttaagag
    49261 gagccgattc tattgcctct gcttataata aagctatgag agaaacagat tctaagtata
    49321 aggtatactt acatcaagat acttttataa ttaataaaaa tttcatacat gatattttag
    49381 agatatttaa aaaaaataca gatgtcggaa tgattggtgt agctggagta aaagatatgc
    49441 ctgtgaatgg aatttggtgg gattctgata aaaaagcagg gaaagtatat gatagtcata
    49501 caggtaaaat ggatatttat gaatttagta actttgaaga atgttttaat gaagttatgg
    49561 ctatagatgg attaattatg attactcaat atgatgtatt ttggagagag gataagtttg
    49621 atgggtggca tttttatgat ttgtcacaga gtatggagtt tagacaaaat aaatacaaag
    49681 ttattgtacc aaaacaaaat aagccttggt gtatgcatga ttctggagta gtaaatataa
    49741 ataatggata tgatgaatat aggataaaat ttgtaaaaga gtacataaat cttgatttat
    49801 atagagaaaa tttttatgaa tttgataaga agaaagcaag taccatactt aagagtaata
    49861 agcatgtaat ggattgtatg aaagaggagc ttacagaaca attaagatta aagaattaca
    49921 aggatgtttt aggtattgtt tctaaaattg ctcatttttc tgtttttaat catactggtt
    49981 tgtattcttg tgaagaatgt gagagagcat tgctagaatg tgcaaataat ttaccagaaa
    50041 tagaaaatac gaaattattt acaaaaaaag atttaaaaag aagaaaagta ttacatgttt
    50101 taagtgaagg atattcaaca ggaggtcata caagactagt taaaaattgg attgaaattg
    50161 acaaagactc tgttcattca gttgtaacta catggcaatc agatacactg ccagactggt
    50221 tattaaaagc aataaatgat agtggtggcg aagttatatc tttggattta atttcagatg
    50281 attatttaaa aagagctgta gctttgagga aaatagctta tgactgggct gatatagtta
    50341 ttttatatgt tcatatgtgg gatacaatac ctgttgttgc ttttggagtt gatgggaaaa
    50401 tacctatttt acatgttaat cactatgata gtactttttg gttagggaca agtattgcag
    50461 atattgtcat tgattttagc gaaactagtc aattaattac attagataaa agaggcatag
    50521 ataaatctga aatattacca atgccattaa aagaaaaaga agtattttca aaatctgaag
    50581 ttagaaaacg atataattta gaggatgatg tgacaataat attgactatt gctagtgaaa
    50641 gaaaatacaa tagtgtaaat gatattaatt actttaaaat tgctaaaaca ttgattgaaa
    50701 atacagataa tacaattatt attgttgtag gagttgatac agagaatctc tattggaaaa
    50761 ctttaagtaa tgttacagat aatagagtta tatgttttgg aacaacagca aatatagatg
    50821 atttttataa gatttcggat atatacctag agtctttcat ggtaggaagt catacttcaa
    50881 aattagatgc aattttatat gatttaattc ctgttaagtt taaaaatgaa gtttcaccaa
    50941 tttttacaaa tatgtggaat tttatagata agtttgatta taagaatata aaagaggtta
    51001 tagacatgat aagaaggtac aatactagtg aatttgacag ggataagata aaagcaaaac
    51061 aatcggaaat aaaacatttt gttatagata aacattgtat tgaaataaaa aactatatag
    51121 acaaaatata taatgaagtt aatcatcata aagttaagta tgatttatat aaaaatgatg
    51181 aaatcgagga ctatcagctt tttgtagcat tatatggcta tatggtaaaa aataaaaaca
    51241 tgtcataggt ggtaaaatga acaatattca tatcaataaa tttgaaaaaa gctgtgaaaa
    51301 aaactgggat tattttgtag aaaataaatc tataaatggt acatttctgc aaactagaaa
    51361 tttccttaat tatcatgagg agggaaaatt cactgaccac tcattaataa tatgtaaagg
    51421 tgaagaaata ctagcagtcg tacctgcatg tgaaacttat gaagatggtg aaagaatatt
    51481 tttttctcat ttagggagta cttttggtgg cattataata agaagtggtt ttaatgatat
    51541 taggcatgta aatgccatta caaataagtt agaaatatat ttacaggaac aaaatttcga
    51601 taaagtatat ttaaaaaata catcaagaat attttgtaaa gaggatactt cattactaga
    51661 atatttttta tttaagaata attacatgtt ttatgatgaa ttaagtatgt ttttagaatt
    51721 aagtaagtat aaagaagata tattagccaa ttttaaatac agtaaaagaa gagattttaa
    51781 atattctttg aagaataatc ttacctttaa aagactgtat agtgatgaag atatagtttg
    51841 tttttttaat ttactttcta attgtttaga tagtaaagga gctaaagtaa tacattcagt
    51901 agaagaactt ttggagttta aaaataatag attaaaagat attgtagaat tttatgcagt
    51961 atatattgat gacattatga tttgtgggag catggtattt aactttcaag aaagagttta
    52021 tcatactcaa tatctagcat caaattcgac atataataaa tattatccaa tgatattttt
    52081 atactataat ctaataaaag atgctttaga gagaaatttt aagtatcttt cttttggaat
    52141 tagcactcta aatagaggca aatacttaga tgagggttta gctacattta aagaaggttt
    52201 tggttcaagt gcaatttgta acagaacata ctataaaaat ataaataagt gagaatcatg
    52261 ttttatagag tttttagagt atagtaaata tctagtacta taatattaca taaaaataat
    52321 tagtttataa agaaggtttg tatatgaaaa gattaatgat tttaggctca attaagtatt
    52381 ttgagaatat tgttatgtca gctaaaagag agggaatata cacaattgtt tgtgataata
    52441 gaattgatac tcctgcgaaa aagatttgtg atgaagcaat agatgttgat gtatttgatt
    52501 ttgataaaat aaagaatata gctatagata aaaagataga tggaatttta actggattta
    52561 cagattcttt aatgaagcca tatgtttata ttgcaaatga actaaatttg ccatgtgtga
    52621 tttcttgcaa tcaacttgaa tctgtaacta ataaggctgt tatgaaaaat tattttaaaa
    52681 ataatggaat acctacaact gattattgta ttattgaaag tttgaaagat ttagaaaaaa
    52741 tacaaggatt aaattttcca cttgtaataa aacctgttga tggttatggt tcaagaggtg
    52801 tatattttgt atcaaacata gaagaattaa tagaaaaatt tgaatattct aaggaagcct
    52861 cgcaagatgg acaagtaata attgaggaat tttatgaaag tgaggaaata caaggactag
    52921 cttgggttca taatggagag tcacatgtat tttatattgg agatagagag cttgtaaata
    52981 tacatacagg aagagctgga aaaccagata gattaattta tccatcaaag tattgttttc
    53041 aatatgaaga agaaataaaa tccatatatc aaaatataac gcaggctttt ggcataaaaa
    53101 atggacctct ttatgtacaa atgttagtgg gagcatatgg aataaaggta tctgaagtaa
    53161 tgccaagatt acctggaggt tgtgactata tggctatttc tcaaataaca gatttagaca
    53221 taggaagttt atttgcaaac tttagtgtga ataatgaagt aaattttgat gaaataaaga
    53281 aatataatat gcatctatca aaatgtgtat atgcattacc aatatacata agacctggca
    53341 caataaaaaa gataaataat atagataaaa tagaaaactt agattatgtc actcaatttc
    53401 tattactagt aaaagaagga gatacaatag gattatatga agatgagaga caggattgtg
    53461 gaagagttta tggagtagca aataatgtat ttgatgcaaa tataaagaag aaatgtattc
    53521 atgaaatgat agaaatactt gatgaaaata atgaaaatat gatagaaaat ttttaaataa
    53581 gggagtatga tagatatgaa gctaataact catgaacaaa ttatgtcatt aaacatttct
    53641 cagaaacaag gatacgagtg gataaaagaa tcctttttaa caaaaaaaga ttgtcaatta
    53701 ccaccaaaaa taagcatggt agaagaaggg catgtatttt acaatgtaat gccgtcccta
    53761 aatcataatc ataagattgg tggaataaaa atggttacaa gattgccagg gagaaatcca
    53821 agtttaaatt cagagatatt tctatataat atggaagatg ctaaattaaa ggctatttta
    53881 gatggcaatt atattacagc ttttaggact gctgctgttg ctgccttggc tatcgataca
    53941 tttgctaaaa aagattttaa tactattgct attatgggtt taggtgtaac tgcttctgct
    54001 ataatgaata tgctttcata tactcttaaa gataaaaata taaatataaa gttacttaaa
    54061 tataaagacc aagcagagtc gtttgtaaaa aagtatgaaa aaaatgaaca atttagtttt
    54121 gaaatatgtg acacacatga agaacttatt gtagattcag atgtagttat ttctactgtg
    54181 acatatacag atgaatattt atcagaattt aaatggttta aaaaaggtgc tttattatta
    54241 cctgtacatg ttatgggatt tggaaatgtt gattatctat ttgataaagt atatttggat
    54301 gattataatc atttgaaaca tctagaaaat atagatagat ataaatattc ttgtgaattt
    54361 tatgatgttt taagtaaaca agctaaagga agagaaaatg atgatgagag aataatatct
    54421 tacaatatag gtttgtcaat acatgatata ttatttgcaa ataaaattta cgaattgtgt
    54481 gaaacactaa gctgtgaaga aatagaatta aaagaaccaa aagaaaaata ttggatatag
    54541 tttatttcat tcatatttac aatagtttat tgtaaatatg aatatgaagt aatatattgt
    54601 tagaaaatta gcatgaatag gatagataaa tttatggata aatataattt aattaggttc
    54661 gtatctattg gaaacgaata tataggaaat ttagttgcat tagaatcaaa taaagcaata
    54721 ccttttgata taaagagagt ttattacata tatgatgtac caaacaatgt aaagagagga
    54781 tttcatgcac acaaaaactt ggaacaagta ctagtttgcc taaatggaag tgtgaagata
    54841 aaatgttatg atggtgtaaa agagactata tttaatttac ataaaaatga tgttggatta
    54901 tatataggaa cgggagtgtg gcatgagatg tttgattttg atgaaaaaac tgttttaatt
    54961 tctatagcat ctgaacatta taatgaagaa gattatatta gagactataa agaattttta
    55021 aagtatttaa ataatgtgta gttattatac aattagtgat gtattttctt aattaaataa
    55081 atttaagata gccacataga gaatagatag attaggatgt gaatttattg ttggttaaat
    55141 ttaataattt attaaaacag ttccaaactc ataaagaaga atatgaacag aagattaagg
    55201 atgtaatgga aagtggatat tatatccttg gaaatgaagt aaagcatttt gaagaagaat
    55261 ttgctaacta tgtaggtagc aaatattgtg ttggtttagc cagtggttta gatgcactga
    55321 taattgcttt tagagcatta ggaataagca aaggtgatga agtaatcgtg caatcaaata
    55381 catatattgc tagtgttatg ggaatcagta taaatggagc aacaccagta tttgtagaac
    55441 caaatgaata ttataatata gattcatcta agatagaaga aaagataaat agcaaaacaa
    55501 aagctatatt agtagtgcat ttatatggtc aagcaagtaa tatgaaagat atacaagaat
    55561 tatgtgataa gtataacttg tatttaattg aagattgtgc tcaatctcat ggagctaaat
    55621 atgatggaaa aatgacagga acatttggtg atataggttg ttttagtttt tatccaagta
    55681 aaaatttggg tgcatttgga gatgcaggag ctatagtaac tagtaatgag gaaatagctg
    55741 ataaagtgaa aattcttaga aactatggct cagaaaagcg atattataat aaatttgtcg
    55801 gatataattc aagattggac gaaattcagg caggtttatt aagagtaaaa cttaaatatc
    55861 taaatgaaat tgaaattgaa aaatcaaaaa tcgtagatag atatcttaat gaaattaata
    55921 atcccaaagt catacttcca aagatagaaa ataattgtac tcatgtatgg catttatttg
    55981 ttttacaagt tgaaaaacga gatacattta tggaatactt aaagaaaagt ggtatagagt
    56041 ctataataca ttatccgata ccaccacatc tatctgaagc atatgcttat ttgggatata
    56101 aaaaggggag ttttaatata gctgagaact attcagataa agttgttagt atacctttat
    56161 ttattggtat ggaagatgaa gaagttagtt atataattaa aattataaat gaatattaaa
    56221 ctactcataa taatatcaaa aataaatttt ttatatatca tttatttaaa tttcgttaat
    56281 tgacattttt aaatattgat atattgtaca aataaaattg aaatatatgg aaaaatatag
    56341 aattaagatg agatttgtct tatattttta taaattaaaa atattttcaa agagtttatt
    56401 ataaaattgt aaactatagt gtttataatc tttgtaatta ttggtaatta aatttaaaaa
    56461 ataaaatatt taattataca caaaaaagat atttaaaaaa tttgttattt attgtatact
    56521 taagttaaaa ctaaataggc aaatctagag aaatctagtg acgcaaagct atagggacta
    56581 aggtttatat acataaacta tgtcagccag ttgccaaaaa gagtcctagg tgtattgtat
    56641 acctaagaaa agtctataat gactgccttt ttggcagtca ttttgttatg gaaaaatcac
    56701 tttatttcag tagaaaatac acataataac atattttacc aattataaca taaaataaag
    56761 aaaaattatc tcaaaaagtt actattttac aaaaaagagc aacttttcga agaaatattt
    56821 aaatacatat taaaattttt ttatattttc atgggacttc attaaaaaaa tattagtttt
    56881 cttactaaat tgatacatta ttgtattaat gtaatggaaa tgcgattaat ttaaataaat
    56941 aaagaagtca ttttttgtaa tatagcaact tcattttttt tattaataaa caaaatagat
    57001 aaaatatatt ttgaggaggg gtgagtgtga atacatatga cattataaaa atgggattag
    57061 atgcaactaa tctaagaagt cagacaatag caaataatat agcaaatata aatactgaag
    57121 gatataaaag acattatata acttttgaag aaacactaaa tgatgctatg cctaaaatag
    57181 aagaaaaaac agacaattct aaaggtttaa gagtagatgg taataatgta gacatagaag
    57241 aagaaaaagt aaatcaagca atggcaacat tacaatataa tgctttgata agttttgcaa
    57301 atggaaaaat agcaatgacc aaatcaataa taagtgggag gtaattagaa gatgagtgtg
    57361 ttcagtggaa tgagaatatc tgctagtgga ttaacagcag aaagtttgaa aatggatatc
    57421 atatcatcca atgtagctaa tataaatgct acaagaggtc caaatggaga agcatatagg
    57481 agaaaagttg tttcatttga agaaaactat gataataaat taggtatgct aggagtaaaa
    57541 gttacatctg ttgaagatga taaatcacct cttaaagaag tatatgaccc atctcatcca
    57601 gatgcaaagc caaatggata tgtagaatat ccaaatgtaa atatattggt agaaatgaca
    57661 gatttaataa cagcttcacg agcatatgat tctaacgtag atacattgaa tgctcagaag
    57721 tctatgatat caaaagcttt ggaaatagga aagtagggat aaattatgcc aattacacaa
    57781 attaacaatt taatgcaagg tgcaaagtta gataatttga ttggagaagc aaagccatta
    57841 actcttaata ataaagaaga aaaaaagaat tttgaagatg taataataga tactatagat
    57901 aaagttaatt ttcaacaagt aacagcagat gatatgaaag aaaaatttat aaaaggcgaa
    57961 gatgtttcta tgcatgaagt tatgttaata ggtcaagaag cacaactatc tatgcaatat
    58021 ttaatagaag ttagaaataa gattcatgat gcatatcaag aaatgaataa ggtgcaaatt
    58081 tagccttttg aacaggagta ataatcaatg ataaccagtt ttaaaaataa gattaaggag
    58141 caagttgcta aatctaggac aaagataagt tctttaaaaa agggaactaa aatagcatta
    58201 ggtatagggg ttattgctat atgtttagcg ctagtattta cagcaatatc tgcgagcaaa
    58261 aataagtatg cagtcttatt ttcagaacta gatgctcaag atgctgcaga tatatcagca
    58321 gagctagagt ctaaaaagat agatactaag gtaaaaggaa gtacgattta tgtacctaga
    58381 acagaagttg ataagttaag gctggagtta gcgccaagtc ttacaggtgg ttctaaagga
    58441 tttgcactaa tggatgatag ttcatcaata gggcttactg atgaagaatt tcagattaag
    58501 aaacaaagaa tgatacaagg tgaaatagaa aaaacaataa agagttttcc acaagtggaa
    58561 gacactagag tacatataac atttggagag tcatcagtat ttgagaagga ggctgttcca
    58621 gggagtgcag cagtttattt gatgctaaaa ccagggacga ctttagaaaa aaaccaaata
    58681 aagtctgtta tggcacttat atcaggaagc gttacaaata taccagagaa aaatgttcag
    58741 gttattgata acaaaatgaa tttattatct gaaggtattt tggaggatga aaatgttgat
    58801 gaaaataatc aaccaataaa tagtggcatt agtgttgata aaaataaggc atctgaacaa
    58861 gcattgaata aacaactaga aaagtctatt ttagaaatgc tagaaccgat atttggtaag
    58921 ggaaaggtga aagctacagt aaatgctgat ttaagttttg atacagctga aaaaactgag
    58981 ataaaaattg accctgataa agttgcaata aaggagacaa ggtcgaaaaa ttcatctaaa
    59041 tctgctgcaa ataatgttca aggtgtagat gctaacatga ataaccaagg aaataacaat
    59101 ggtactaata cagaagatag tttagatgag agttttgagt atgaaacagg taagattgaa
    59161 actcacacta tagttgcgcc tggagaactt aatagattga cagcttctgt tgcaatagat
    59221 ggaaaaatag ctaaaggtgt tcaagctgat gtagaggata ttgttaataa tgctataggt
    59281 atggatggag cgaggggaga tactcttagc gttgtttcaa tggtatttga cccagaaggt
    59341 aagaaagagg ctaaacaaga gctggaagag attaaaaaag aaggatttaa aaagaacata
    59401 ataaaagcag ttattggagt agtagcagta atagcagttg gagctattgg atacttaata
    59461 tataagaaaa gaagtgaacg agaagatatg gattatgaag atgaagatta tatttctaaa
    59521 tctgattctg ttgataggaa ggataatcct ctattaggag atgatccaga actgacatta
    59581 gaggaagctg ttaaaatgta tgcagaagaa aagccagacc aagtaacaga gataataaag
    59641 acttggttaa atgagtaagg gggatagaaa gtgtccacgg aaattacaaa tgttaatgcg
    59701 tttgacttaa gtgatataaa tgaaagtgat aagaatgaga aggtagaagg tgagggttta
    59761 aaaaaagctg ctgtattatt aatgacatta ggcccaaatg tgtctagtga tataataaaa
    59821 agcttgcctg ataaacaagt tcaaaaaata ggtttggaaa ttgcaaatat ttcttcaata
    59881 gcttcaaaag aaagaagaga aatcttaaaa gagtttgtag aaataaatag ggcaaaagat
    59941 tatgttatag aaggtgggct tgaatatgca agagagttat taagtaatgc tttaggaaat
    60001 gttaaagcaa acaaattact tgaaggtata tcaataaata caagtacaaa gccttttaaa
    60061 catattataa aactagatgt aaagaagata ttagaaatac ttaggaatga aagtgcacaa
    60121 actatagccg ttttacttgc acatatggaa ccagaaaatg gagcagaagt tttatcatac
    60181 ttagattttg atttacaaaa tgaagtagct atgagaataa gctcaatggg ttcaatatct
    60241 ccagaagtaa taaaggtaat tgaaagttca ttagaagata aattacattc aataagtggt
    60301 gatgatttta atgattatgg aggggtgtct accttagttc aaatattgat taattctgat
    60361 agaaaaacag aaaagaatat tttgggaact attgaagaac aaaacccgga tttagcagct
    60421 caaattaaat ctcatatatt tgtctttgaa gatattgtca agttagatga tataagcata
    60481 caaaaagtgt taaaagaagt gactatgaaa gatttagtat atgccttaaa aggtgtagat
    60541 gatgagattt cagatgctat atatagaaat caatcttcta gagcagcaga tgcacttaaa
    60601 gaagaaatgg aaatggttgg tgttataaag gttacacaag ttgaggcttc tcaacaaaag
    60661 atagctaata tcgtaagaaa acttgaaaga gaaggtgcca taactattgt aaggaatttt
    60721 ggtggtgact ttgttgaata ataagattat taaaagtaaa aaagcattat ataaaggagt
    60781 gctagattta accataatag ataaagttag agtgggagaa tcaaatgtaa ataaagaaaa
    60841 tgattgtaga tttagggatg aggtaataaa agaagctata gaatctgctg agataaaaaa
    60901 gaatgagata ttagaagaag caaaaataaa tgcacaaaat atagaaaagc aagcatatga
    60961 aaaagggtat agtcaaggtc aaaaaaatgg atatgaggat ggatataaag agtcatatga
    61021 tgaatatacc caaaaagcta aagatgaagc agattttata aaaaatcagg caaatttaat
    61081 cttattacaa gctaatgaga agatgactga gtacataaaa gaaaaaaata aagagattgt
    61141 aagacttgct attaatatgg ccagttctgt tttaaaaaag catttcgaag atgaagaatc
    61201 tatgagtgat ctgttaaagc aaattattca agattatgaa ggaagtagtt catttatagt
    61261 aagatgtaat tctttctata aagataatat agagaaagag tttgaattat tcaaagagga
    61321 aacatcacta aaatcaagtg tatttgttat tgcagatgat agtatagata aaggcaatgc
    61381 tattatccaa aaggaaaatg gaagaataat agttggtatt gattgtgcta tggaaaaact
    61441 aaaagaagaa ttgcttggtg aataaagtat gtataaaact gatatatcta tagattttga
    61501 caaaataaat aagaaaatag aaaatttaga actcactata tcagaaggta gagtaaagaa
    61561 gataatagga cttactgtag aagttgaagg aataaaagct tttgttgggg agttatgcgt
    61621 tatatacaac caagttaata aaccagtgaa ttgtgaagta gtaggtttta aagataaaga
    61681 agtcatatta atggcgttgg gagaattaac attgatagca cctggttgta aagttatttc
    61741 taaggggata cctttaagtg ttatgtgtag tgataattta ctaggtaaag tacttgatgg
    61801 tcttggaaat cctatagaca actcagatgc tgttttagga gatagataca acctgaacaa
    61861 tgaacctcct gatccaatga agagaaaaaa gatacgaaat ataatggaaa caggtgtaag
    61921 agcaatagat gcatttacta cttgtggtga aggacagaga atcggcatat ttgcaggaag
    61981 tggagtaggt aagagtacga ctctaggtat gattgctagg aatgcaaaag cagatgtaaa
    62041 tgtaattgct cttattggag aaagaggaag agaagtacta gattttattg ataaagattt
    62101 aggtgaagag ggaatgaaaa aatctgttgt tgtgtgtgca acatcagata aagcccctct
    62161 agttaggtta aaaggtgctc ttactgctac tgcaatagca gaatatttta gagaccaagg
    62221 caaaaaagta atacttatga tggattcagt aactagattt gctatggcac aaagagaagt
    62281 tggtgtagca ataggagagc caccagctca aaaaggatat acaccatctg tatttgcaat
    62341 gttgccaaaa cttatggaga gaacagggac atcagataaa ggttctataa ctgcatttta
    62401 tacagtatta gttgatggag atgactttaa tgagccaata gcagatacaa caagagggat
    62461 acttgatggt catatagttt tatctagaga cttggcaaat aagaatcact atccttctat
    62521 agatgtatta aacagtttaa gtaggcttat gaatgaaatt gcttcaaaag aagacataaa
    62581 aatagcgtct tttgcaagag acatgcttgc tgagtataga gaagcagaag atttgataaa
    62641 tataggtgca tatgcttcag gtacaaataa aaaaatagat gaagcaatct attatcatga
    62701 gcatattatt aattttttaa aacaagggat aaatgaaaag agttctttta atgaaactat
    62761 aagtagtttg agaagagttt ttgaataaac aattaaaaaa atatttgaat aggttgtgat
    62821 ggaattggat aaaaacttta agtttagatt acagaaagtt ttagacttaa aagtgaaaga
    62881 tgaagaagag ataaaaatgg aatttgctaa gattcaacaa aaaaaaatag atatagagac
    62941 taatttagaa aacttagaaa gtaattatag caaatattct ataagtaaaa ataacgatag
    63001 tattcaaaat caaaaaataa ctattaacta tttactagct ttaaacaatt ctataatgga
    63061 tttatcagaa gagttggata agtcaacaaa tgaacttgaa aaagctagaa agcagcttat
    63121 aagcaaacag atagagagaa aatcattaga aaaattaaaa gaaaaaaagt atggacagta
    63181 ttataaagaa gaaaatttaa aagaacaaaa cactaatgat gagtttgcaa gtatgagtta
    63241 tttaaggaat agacaagttc tataagaata gtaggaagtg aggatattat tgtatgaaga
    63301 tacaagcaga ttcttataat attattaaag atattgggga tagaaaaagt tcatctaaga
    63361 acaaaaatat aaaaaataat aaatttgaag ataatctata taaggcaaca gaccataaaa
    63421 aagttaaaga tagaagggaa gtaagtaagc aaaatattag ctcagataaa ccggaaaata
    63481 gtgataatga gtgtcattta gatgaagata aaagtaatca cttagaagat gaaaatacat
    63541 atgaaaaaga ttgtagtaag aataatgaag ctttgcagca attactgaat cttttaaagg
    63601 ataattataa aaaagataaa gatataaaca ctatattgaa taatatagaa aaactaagta
    63661 tatcagatga attaaaacaa gaacttaagc ttaataaaaa tatattaaat aagattgcaa
    63721 atcaaaattc agagctaaat aaagctaata taaataactc taatgatata gaaaatttag
    63781 acatagttaa attaagagaa cttttggaag ataatgctaa taaagatatt gaagtaatta
    63841 ctaaaactac agaaaatgat accaaaaata tagatttgta tagttttgat agcaatagaa
    63901 tggataatct taactcaaat aaacagaaag atgatagctc tgatattttg gaaaaactag
    63961 caggggtaaa tggaaataag agtgggaatt ttggacaagt aataaataaa aatgttgata
    64021 tgaataaaat taaaaatgat aatgtcaatt taaaacagat agaatcaaat gtaatggatg
    64081 actctataaa agctattaag catatgaaaa caaatgatat acaagaattg acaattaaat
    64141 taagaccaaa agaattagga gatatgaata tacaattgtt aaaagatggt gaaagtatga
    64201 gagctgttgt gactgttttc aataaagatg tctttgactc tataaataaa aacatagcag
    64261 atttaaagca acatcttgaa cttactaatg taaatataaa agatgtatca gtgcaaatgc
    64321 acagcgataa tacaaataca tctgatacct ttgataaagc atttgaacaa cagaatagac
    64381 aaaataacca agaaaacatg agtaagaaga atacaaatga taagcataat aatgtagtca
    64441 tagaagatga cattaaagaa aatactattg atgatgatag agtagattta ctagcttagt
    64501 aagggggaag tattgcatgt acggaatagc aacggctttg gcaggaactc agggaaacta
    64561 taggtcaaat aacttaagcc aacttgaaag aaatattaat gatattgcca ataaacaagt
    64621 tagaagcaaa ggaaatcaga cagtaacaga caatgggact ccaattatag gacaaggtga
    64681 tgatgctgat aaagacttgt ttatgaagat acttgtggca cagatgggta atcaagaccc
    64741 aatgaatccg caagacccaa cagaatatgt gtcacaatta gcacagtttg caactttaga
    64801 aaagatgtca gctatgaatg agaagctaga tgtactttta gccttaagta attccactct
    64861 aataaactct gctttaagta tggcaacatc attaattggt aaagaagtag aagtatctgg
    64921 ggaagagaaa gaagatgaaa acattgtagg agtagtaaag tccacatata taaaagatgg
    64981 ggaagtacac ttagaattag aagtagatgg aagtgacaaa actgtaggtg ttaaatatga
    65041 aaaattactt aaaataggag aggtagatga aaattcagga gaagaaaatg attcttcaga
    65101 acacgaatct ccagaagaag cataatatta aatgagaaaa gaggtaaatt catgataaaa
    65161 gcaatgtatt caggtgtaag tggaatgaaa gcaaatcaaa caaaattaga tgtaataggt
    65221 aacaatgtag ccaacgctgg aactacttct tttaagaaaa gttcagctag aataacagat
    65281 tcattttatc aaactgtact atatgcaagt gctccaacag ctgcattagg aggaacaaac
    65341 ttaggacaag taggtgtagg tagtaagata tcaagtataa ataaagatat ggtacaagga
    65401 aatgtacaac caactaatag accatctgat ttaatgatag atggagatgg atatcttcca
    65461 gtagtaagac aaggaacagt tatgtatacg agagatggtt cttttaattt agatacagga
    65521 tttaaagcag ctgatggtgc tttgaagaat attaaaggtg gaagacttgt aaatggtgat
    65581 ggatatatgt tacaaggtat gatttatgat ggggaatata aagctgatac tggagaattt
    65641 gttaaaaagg gtgatgctaa aggaaaagag cctattgtaa taccacttca aagtataagt
    65701 cctaaggatg gaacagttca aaatgtacta gagtataata tatcaaagga tggaacagta
    65761 gaatttttat tgagtgatgg tcaaagaact caatttgtct atgatatacc tgatggtgct
    65821 aaggtaggag atacacctgc tggaatagat aaattaaaag gtacaataca aaaagtgcaa
    65881 acatatgcat tccaaaatcc agcaggacta gatgcagaag gaggaaactt gtttaaacca
    65941 tcagcaaact caggagaccc acaaatagca ggagctacag gcacaataat acaaggggca
    66001 atagaagctt ccaatgtaga tatagcagaa gaatttacag aaatgataat agcaagtagg
    66061 tctttccaag caaacagtaa aataatatcg acatcagacg agatacttca agaaataata
    66121 aatcttaaga gatagtaggt acatattatg ataagagtaa cggatttaaa cggaagaaaa
    66181 tacatattaa attcagacct tatagtgagg attgattctg taccagaaag taggattctc
    66241 cttacaacag gagaaaaaaa ccttgtaaaa gagtcggtag atgagatagt agataaagta
    66301 ataaagtata aaagaaaaat aaatgtaggt tatattagga gcgaaaaata atgaaaaaaa
    66361 cagattcact gacatttatt ggactaatag tatctacagt attagtttta gttggtgccg
    66421 caaaaggaag tagttcaggg ttaaagaatt tttttgatgt ttcatcaata ttaatcacag
    66481 tgcttggttc atttggagct ctaatgatta catttactat agatgatata aaacttataa
    66541 aaaatgcatt acaatactca tttaagacaa tgagtgtatc aaagttagat ttactagaac
    66601 aatttaaaac actttctaaa aaagctagaa aagaaggtct tttatcaata gagagtgatg
    66661 taatgggaat agaagatcca tttatgaaga aagggttaga gctgtgtatt gatggattgg
    66721 aaatcaatga gataaggtcc atcttagaac tagagataga ttctgttgaa gatacaaata
    66781 acagatactc taaactattt aaaacttggg gaacctttgc acctgctttt gggatgttgg
    66841 gaacactaat aggtttaata caaatgttag ctgaccttac atctccagat ttaatagcat
    66901 ctggcatggg aaaggcatta attacaacgt tttatggttc tttacttgcc aatatcgctt
    66961 tgaacccaat tgcatataat atagatgaga agactgaaaa agaaatttat gtaaaggaaa
    67021 tgatgttgga aggtataata agcatacaat ctggggagag cagtatagta gttgaggaac
    67081 gtttagccac atacctttca aacaatgaga agttagaaat tatgaaatcc aataaaaata
    67141 cagaaagagc aatgagcaat ggcgcgtaaa aaaaataaga aaaaggatga gataaatcca
    67201 gatgcatggc tggctactta tgcagatact ataacactga ttcttacatt tttcgtatta
    67261 ttgtatgcaa catcagttgt agatatggaa aaatttaaaa acatagcaga tgcgttaaaa
    67321 ggtcagtttt ctgggacaag tatatttagt acgggttcaa gtacaagtga gaaatctcca
    67381 atagacagtg ttttagtgga taaaaatgat aaatcaaatt tagaacagga tttaaaagat
    67441 aaagttaata attctaactt acaaaatagt gtaacagtca aagatgatag tagagggatt
    67501 ttactagagt tagatgattc aattttattt gactctggga tttctgagtt aaaagtagat
    67561 agtaaagcta ctcttaataa agtatatgac atgataaaga tgatgaaaaa taagatagtt
    67621 atagaaggcc atactgataa tgtacctgta aaatcaagta cacatgaatc caattgggat
    67681 ttatcttcta gtagagcagt aagtgttgta agatactttg tagaagaaaa gggcatggac
    67741 cctagactat tttcggcaac aggatgtgga gagtatcaac ctttggtttc aaatgaaaca
    67801 gcaaagggaa gggctgagaa tagaagagtt aatatactta taactattga ctaggaggaa
    67861 gaggtttgtt caaaaataaa aaaattatta taattatttt gatactgatt attttctcag
    67921 cgggagcagg tttttttata ttaggagaag gtggaaataa acaagttgac aagattgcag
    67981 atttgtttat tccaacagga aaaggtaaag atgaagtaaa gaccgaaaat cttgacttag
    68041 aagagatggt attaaagcta gctgatgaag gtgtaagata tttaaaagta tcaataactg
    68101 tatcttatga ttcttcatat aaagatatag aaaaaaatac gcctttaatt agggataata
    68161 ttataaattg ttttatggca aaaagggcag atgattttac tgctgataat ttaaagaaca
    68221 taaaagaaga aataaaaaat acattaaata tacaactagg tgaaaatgta attcaaaata
    68281 tatatttcac aaatatagta gtgcaataaa aggatggtaa gacatgatac tttatttact
    68341 aaaaatatta atatgtatcc caataatttt aatattgata gtcttatctt taaaaattag
    68401 ccaaggaact ttattaaaaa aatataatga taaatatgta aaaatactag atattgtaaa
    68461 tataagtaaa aacaatagca taataatttt aaaaataggt gaagaaggat gcattatggc
    68521 atcttcttct tctagcatga gtaaaataaa agatttgacc aaagaagaaa tattaaaaat
    68581 agaaaacgac attaaagaaa gaaattttaa aattcaagat tttaaaatgg aaagaattaa
    68641 aaagaaatat gatttcagta gatatattgg aaaatttaca aaaaaggaag ataagtaaat
    68701 ggaactatta tcaaaattac ctttggctga tgtaccatat acaagttcaa tgcaattgtt
    68761 tttatttcta actgcattaa tgtttttacc atttgtaatg ttcatgatga caagctttgt
    68821 cagaatagtt ataagtttat catttttgaa atcagcatta ggagcacagc aagcaattcc
    68881 aagtcaaatt ttggtaggac ttgcaatagt attgacaata tttataatga gaccagtatt
    68941 aaatgagata aacgaaaagg cattacaacc atatatgaaa gaagaagtta ctatggaaga
    69001 agctatgaag gaagcagaag gacctattaa agagttttta ttaacacaaa ccagacagac
    69061 agatttagat ttatttgtag aacaggctgg tttaaaagaa aagaaattaa ctcgtgaaaa
    69121 tataccacta tctgttgtag ttccagcatt tgctataagc gaactaaaaa ctgcttttca
    69181 aataggtttt ttaatatata taccattttt gataatagac cttgttgtgg caagtgtttt
    69241 gatgtctatg ggtatgttta tgttgcctcc agtcatgata tcattaccat ttaagttatt
    69301 attatttgta atggtggatg gatggaactt gatagtaaaa acattgatat tgggatttgg
    69361 ataggagaaa aatagtatga gtgaatttat gataatgagt gttcttaaaa atggcatgtt
    69421 tacaggagct atgattgcag ctccagtact cattgtttct cttgtagttg ggcttttaat
    69481 aagtgtgttt caagctacaa ctcaaatcca ggagcaaact ttgacttttg taccaaaact
    69541 aatagctatt cttttagtag tagctattgg tggaagctgg atgttacata ctcttattag
    69601 ttttacttct gagatattca atatgatatc tcttataact aaataagtag gatacatatg
    69661 atttttgtat ttattagaat agtagcattc tttggaacac taagaatact atttccagct
    69721 ggtacacctg ctttatttaa gtcactcttt gcaatcatta tatcaatatt gatttcaagt
    69781 actatgcaaa ttgaatatgc aacaaatata gacaacattg tattgtttac cttatatggt
    69841 gtaaatgaga ccataactgg gattatgctt ggatatataa ccaacctatg tttttatagt
    69901 atcagaatgg cgggttctat gatggaccaa cagatgggat tatcaatgat taatatgttt
    69961 gacccaaatt caatgactca gacaacttta attgataatc ttatgaactg gacagcactt
    70021 atgatatttt ttagcatgga tggtcatcat gttttaatta gaggtataag gtatagtttt
    70081 gagttaattc caataggaaa accatttgta gataataaca tagattatat aataaacata
    70141 tttgtgcagt gctttttaac tggattcaaa atagcaatac ctattgtact ttgtctgctt
    70201 atggcagatt ttattttagg gcttatatca agaagtgtac ctcaattaaa tgtaatgata
    70261 gttggtatgc cattaaaaat attggttggt attgcattat ttatcatatc aataccttta
    70321 attgtcaatc aaataagtca tttattaagt caaataccaa agatgtatga gggaactttt
    70381 gcactagctc ctatgttttt tatgggttca gcagataaaa cagaagaagc tactccaaag
    70441 aaaaagggag aacaaagaaa gaaaggtaat atagcaaaga gtagagaatt acccgttgca
    70501 atgactctac ttgcattcac cttattagta cctacattat tttcatatgt agtagataca
    70561 cttaaatctt cgcttaatta ttttttgagt ctagattttt atatgaacat aaattattca
    70621 aacctagaga aattagttat agcaggatta atggattttt ttaagatatt tttaccaata
    70681 gctattccct ttttagtttt aggcataata gcaaacctat ttcaggtggg aatactgttt
    70741 actggtgaaa ctttaaaacc aaatttatca aaattaaatc caattagtgg attcaaaaac
    70801 atgttttcta tgagaagttt gtcaacctta ataaaggata cagcgattat atctattttg
    70861 gcttacatag gatatacatt cttccaagat aattatttag atatattaaa gctaggtaac
    70921 atatacctac caactttaat gtacacagtt aaagacttag tatattcaat attgagtaag
    70981 atttgtgtag ctatgatagc tatagcagtt gcagattatg tttatcaaag atacagtcat
    71041 aaaaagcaac tgagaatgac aaaacaagaa gttaaagatg aatataaaaa ctcagaagga
    71101 gacccagaag taaaagctaa gataaaacaa aaacaaagac aaatttcgtc tcaaaggaca
    71161 atgcaagcag taccaagtgc tactgtaata gtaaccaatc caacccactt atctatagca
    71221 gtgagatatg aaaaagggaa agaccaagct ccagtagtgg tggcaaaagg tgcagattat
    71281 ctagctttta aaataaggga aattgcaaag ggaaataaca tccctataat agaaaacaaa
    71341 cctattgcta ggttgttata taagcaagta gaaatagacc aagaaattcc agaggacatg
    71401 tatcaagctt ttgcagagat attagtggca gtatataaaa tcaaaaatag atacaaagtc
    71461 cccaaaaggt aggataagta atgaataagt ttaatttaaa ggaaaatatg gatgtaatag
    71521 tggcatttgg tgttgtaggg attgttctta tgatgatagt gccattacct acatttatat
    71581 tagatatttt actggcaatt aacataagtt tatctgtgct aattttacta atgacattat
    71641 ttacaacaaa tgtacttgat ttatctatat ttccaacagt gttacttgtg acaacactat
    71701 ttagattggg attaaatctt tcatcaacta gattgatttt aacacaggga tatgcaggtg
    71761 aagttataga ggcatttgga agttttgttg taggtggaaa ttacgtagta ggaataatta
    71821 tattcttaat tatattaatt gttcaatttg ttgttataac caatggttct ggaagagtat
    71881 ctgaagtaac agctagattt acgttagatg ccatgccagg taagcagatg agtatagatg
    71941 cagatttaaa tgcaggagtt atagatgaca aaactgctag aaaaagaaga aaagagcttc
    72001 aacaagaagc agatttttat ggttctatgg atggagcaaa taagtttgta aagggagatg
    72061 ccatagcagg tcttatagta acagcaataa acataatagg tggaattgta ataggagctg
    72121 taatgctgaa tatgactctt atgggtgcag cacagacata tgtaagactt actatagggg
    72181 atggtcttgt aagtcagata cctgctctat taatatctac atcagcaggt ataatcgtaa
    72241 caagagcttc tactgatgaa aactttggtg acttagtagg taaacagtta acggcaatac
    72301 caaaagcagt aatgatgact ggttgtgttc taatcgtact tggtatgatg cctggattac
    72361 ctaaaccagc atttttttca ctaggtatag gagctatagc agcaggttac tttttaggaa
    72421 gagaaaagaa agatacttta gaagacttgg agtttgaaaa acctgatatg gtaaacccag
    72481 ataaaaatga agtagaagat gtaacaaatt taataaatgt agaatcaata gaagtagaaa
    72541 ttggatatgg tttaatatcc ttagctgatg aatcagcagg aggagattta cttcagagaa
    72601 tagcatcaat aagaagacaa tgtgcaatag atatgggtat agtcgtacaa cccataagaa
    72661 taagagataa cttacagtta aatccaaacc aatacaatat aaaaataaaa ggaaatgtag
    72721 ttggtgggta tgagataatg cctaatatgg ttttatgtat ggaccctatg aatcaaggat
    72781 ttagtatatt tggaataaag acaattgaac ctacttttgg aatagaggca ctttggatag
    72841 aaagtgacaa ggtagaagat gcagagttaa agggttatac agttgtagat tcatccacaa
    72901 tacttataac tcacttacta gatataataa aatcaaatgc acacgaatta ctgggaagac
    72961 aagaagttaa gactattata gatgcagcaa gagaaaatta tagtgctgta gtagatgaat
    73021 tgataccaga tttgatgaca cttggtgaaa ttcaaaaagt acttaaaaat ctgttaagag
    73081 aaaaagtaaa tataaaggat agagttacaa tacttgaaac gcttgcagac cagtctagaa
    73141 atacaaaaga tatagagctt cttactgaat atgtaagaat agccttggct agaagtattt
    73201 gtaataattt agttgatgat gataagacaa ttgtagtggc tacattgtct ccagaaactg
    73261 aagagttggt atctaataat ttacagaggt ctgtaaatgg aacttatcca gcagttgacc
    73321 cagaaaatac aaataaaata tttgaaagta tacaagaagt aatgagcaat gtatatttca
    73381 atcataatat accagtaata gtagtatcac caaagataag agctccattt agaaaattag
    73441 ttgaaattgt atatcctaat ttgactgtat tatcattaaa tgaaatacct aacgatatta
    73501 aaatcaaagc agaaggtgtg gtgagcatat atgatgacga aaaagtatac agctaacaca
    73561 attcaggatg ctatgaatct agccaaaatg gaattgggtg acaatattac attaatagat
    73621 aaaaaagagg taagaaagtc tggaatacaa ggtatctttt caaaaaaaga tattgaacta
    73681 actattggat gggaaaagag agaaaatgta gaacaaaaag atttaaaacg agagatagaa
    73741 caattaaagt caattattaa caatatgggg tttgataata agaatgataa tgatatagat
    73801 aaaatatgta aaaatctact aagtttagaa ttgaatgaag aaattgtaga atctataaga
    73861 attgatttgc aagaaatgaa gttcaatgga atcgatacaa gtaaaaattt agtagaaatt
    73921 ttaaagaaaa agattaaaat agaaaatcaa gtaataaatg gtaaaattgc tctagtcgga
    73981 ccaccaggag taggtaaaac gactacaata gcaaagttag ccgcaaaatt agtttttgaa
    74041 gaaaataaaa aagtaggagt aataactata gatacataca ggattggtgc tgtagaacag
    74101 ttgaagatat atactgatat aatgaatatt ccctttaaag gggtaataag tcctgatgaa
    74161 atggaattgg cacttgacga gatgaaagat tgtgatgttg tattaataga tacaacaggt
    74221 agaggctaca aaaactctat gcaaatacta gaaatcaaaa atcttataga taaagctgaa
    74281 actgataata tacatttagt tttgaattgt acaacaagag aaagtgatac aaaagcaatt
    74341 atagattcat atagaaatgt gaattttaaa agcttaataa ttacaaagct agatgaaaca
    74401 ataacatatg gctcaatatt taacataatg aattatgcgc aaaaaccaat atcatatatt
    74461 acaacaggac aaaatgttcc tgatgatatt ataaaaccta atgaagataa gattataagg
    74521 ttactattag gagttgaaag tatatgatag accaagctca aattttgaga aaaatagcaa
    74581 tggaaaaaag aggacttgat gagtttatag tagagaatga gaatgtacct aagataatta
    74641 caatagcttc tggtaaaggc ggtgttggaa agagcaatct cgctacaaat ttgtctatat
    74701 gcttgaccaa acttaataaa aaagttctta tattagatgc agacatagga atgtctaata
    74761 tagatataat aatgggggta aatgtaaaag ggactataat tgatgtaatt aatggcgaaa
    74821 aaaatataga agatataatt tcacagacta agtatggtgt aaatataata tctggaggtt
    74881 ctgcccttaa tcatatagaa gactttacag aagctcaaag aaataagttt atacatagca
    74941 tagaacaaat tcacgatgtg gattttataa taattgatac aggagctggt atgagcaaaa
    75001 gcctattgtc atttatatac tgtagtactg aatttttctt aataacaact ccagaaccga
    75061 catcattgac tgacgcatat agtttattaa aagctataag taattttggc ataaagagaa
    75121 gtgcaaatat aataatcaat agggtaattg atttagaaga agcaaaatct acatacaaaa
    75181 gaataaaaat ggttgtggac aaatttctaa accttaatct agaattgtat ggatatataa
    75241 tagatgacaa aaaagtaagt ttatgtgtaa aaaaacagat accattcatt ttagaatatc
    75301 ctacaagtat tgcatcaaaa tgtattatag ccatagcaaa gagaatggta agtcagtcaa
    75361 gagaagatat tgttgataat aaaagttttc taagaaagat gtttagtata tttaaaagct
    75421 aaggaggcgt agttaatgaa tagagaagaa ttaataaaag agaatatgcc tcttgtaaag
    75481 agtatagcaa gaaaattttt tataccaggg aaaggttttg aatatcaaga cttagtaaat
    75541 agtggagtca ttggattgat tgatgcaata aataaatttg atgctgaaaa aggggcaaag
    75601 ttttctagtt actcttatat aaaaataaaa tctgctatat tagatgaaat tagaaatcaa
    75661 agtccaattt ctaaacataa tctaactaaa gtaaataagt ataatagagt ggtagaaaag
    75721 ttgcaatcta aattattaag agagccaact tcatatgaaa ttgcaaaaga attaaaggtt
    75781 tcagaaaaag aacttcatga tatcgaaagt aatatagata tgttaaatat tgtatcatta
    75841 aactatgtaa tctttgaaga tacaaatgaa actgtacaag atgtaataag tgatagagaa
    75901 gaggaagctc cagaaaatat aatagaagaa gaagaaaagt tagagattct atccaaagca
    75961 attagtaatt taaatgaaag agaaaaatta atactttcac tgtactatta tgaagattta
    76021 aatctaaagg agatagggaa agtgctaggt gtttcagaat caagagtttc acaactccac
    76081 agaaaatcaa taagaaactt aagaaacaag ataaaagaac ttaaatattc tatatagatg
    76141 gtgattgata agatgataca aattatatta atagtagtgt ctattttaat aatagtaact
    76201 atagttataa atttacataa ggaatcaaaa aataaagata acagatactt tgataaaata
    76261 tttgagcaag aatatgaagc aaatgataga ttaataattg cagaaaaaag aagattcttt
    76321 ttagacaaag tacttgcaga aaaaagaatt aatagtcata taaaagttta tgaaaattat
    76381 aacctaataa aggctaatga agaaagaaag gaaaacatat ttatagaatc aaaaaaggaa
    76441 gtaagacaag aaaatgagtt atctcttaaa gtgaaacatc ttataagttc aggttatgat
    76501 gatgtggaaa tatgtaagat gctagatatt ggaaaggggg aactgttatt aataaggagt
    76561 tgttacaaaa tataaggata ttattatgtg ataaaaaagt attcttagga ataggtattg
    76621 gtatattaat atcaacttta tgtataatgc tttttagtaa taatgatatg agtaaggcag
    76681 agatagaaaa aaaggccaga gcgttaggca tgaaatatac aagtgagatg aaagttttag
    76741 aatagatgat attgtttaga catttacaaa aaaggaggtc ataatgtgat aagaggatta
    76801 tatacagcag tttctgctat gataactaat caacaaaagc aaaatgttgt tgtcaataac
    76861 ctagctaata tggatacaaa tggatataaa agtaaacaac ttttgactaa aagttttgat
    76921 gaattaaagt tggagggtta caataactac gcaaatggaa ctaaacaaaa gcagattata
    76981 ggcgatataa gtccaggtat ttctatggat gaaactatca caaattttaa tcaaggacct
    77041 ataaaaacta ctgataataa aatggatgta gctattcaag gtaagggatt ttttctagtt
    77101 agtgatgcag ctggaaatca attttacact agaaatggga acttcagaac agacaatcaa
    77161 ggtgacctta taacaagtga agggtattat gtacttggga cgaatactgc tactggtgct
    77221 gtaggtcata taaatgtagg aaatcaaaaa tttgaagtgg caaaagataa tacaatatca
    77281 ctagacggaa atgctatgta taaatttaat attgtagatt ttaataacta caataactta
    77341 aaaaaagaag gagataactt atattctgga ggaggagcta tgaaagtaaa taatgcactt
    77401 acaatacaaa gtgcgataga gtcctctaat gtagatatgg tatctgaaat taataatatg
    77461 atgacaatat caagagaata tgaggcaaat caaaagataa ttcaggctat ggattctaaa
    77521 ttagcaaaaa tagcaagtga gattggttca gtaagatagg taataggagg tgaattttta
    77581 tgtacacaat gttttatact agtaaaacag ctttatcagc aaatcaaagt aaactagata
    77641 taatatctaa caatatagca aattctgatt caacaggata taaaaaaata aatatggaat
    77701 attctgattt agtggatgaa gtactaaata gaccatcata tcctacaaat ggcaatgata
    77761 tatcgactgg aacaggagct aaggcaacag ctcccatgag aaattatgaa caaggtgcat
    77821 tggctcctac agatagtaag agtaatttgg caatagatgg agaaggattc tttagagtga
    77881 taagaaaaga tggtacatat gcatatacaa gaaatggtgg atttaatgta gatgctttag
    77941 gtaagattgt agatgataat ggaaatatat tagatgtcca atttgatgca ggatataact
    78001 ataataatac aaatatagat agtacaaacc tgacagtttc aagaaatgga gagctattcg
    78061 tagataataa aaaaatagga aaaatcaact tatatcaacc tataggaact caaaatttta
    78121 tatctgaagg agatagttta ttcgtcgcaa ctgatgcagc acagattaaa caagttgaga
    78181 aagtcgatat agttcaaggc tatagagaga ggtcaaatgt ttctttacaa gaagaatttg
    78241 ttgacttaat agccactcaa agagcatttc aaatgaactc aaagggaata aagacagcag
    78301 atgaaatgtg gcaaatagcg aataatttaa gagctaaata attatgtaag gtgaggaata
    78361 ttcatgaatg atatgaaaga gtacgatttt ggcaaacctc agagttattc aagagaaaat
    78421 ttaacttgtt taaatttttt attagctgaa ttttgtaaaa aatataaaaa ctatataatt
    78481 tatgaactta agtgtaattc tagtatggtt gttgatagta tagaccaagt aaattatcag
    78541 acttttttag atagagtaac ttcttcatgc gtagtagtac aaaatgcaat ggaacctgtt
    78601 atgaaaaact tttcttttag aatagataga agtgtagctg atatgtggat tgatataact
    78661 tctggaggaa ctggagttgt aaaggataat gatagagaac ttacagaact tgataaaaaa
    78721 gtgcttttac accttatgga tgatttagta agaaatatgc acttatttga gggttttgaa
    78781 aatatacaag tattggatac acatacacat attaatttgc cacaattatg ttctccaact
    78841 gcaccagtat gcgttgtaga tttaaaagtg ctaaatgata atgagtatat tggaagtgtt
    78901 tctctttgct ttccatacaa tggtttagag gctctgttag aaagtatatc tgttatagaa
    78961 ttttttgata atgatgtagg agatgattca gaggaattta cccaaaaaat ctataatagt
    79021 gtatctaata tagaattatc agttattgca gagataggaa aagtatcaat taatgttgag
    79081 gatttactca aactagaagt tggagatgta atagtaacaa ataaaaaaat aaatgattat
    79141 atagatatat ttgtagaaaa ttcaaaatca tacacagcaa caccaggatt tatatcaagt
    79201 aaaaaaggtg taaaaataaa tgatgctgtt ggaaaagagg tgtagttatg gacaatagta
    79261 atcttatttc agatgaagaa gcaaagatgt tattaaatga taaagttgaa agtgaagttg
    79321 atggagatga tgagttagcc ttagatgtct ctgaagttaa tcgaaataat atacaaagga
    79381 tacttgacct taagttagaa ttatctgtag ttataggaag aactaagatg actctaagag
    79441 atattttaaa tttacataaa ggttctctta ttgaactgga tactttggca gaccaagatg
    79501 tggaaatact aatagataat aaggttttgg cttatggaaa agtagtggtg gtagatttaa
    79561 attttggtgt aaagataaca agtatagtaa gtgaagaaga catggtaaaa tctcttgttt
    79621 agagataaca tcaattaata cttaaggcat gaggtggtac ttattttaaa cttaaatgat
    79681 ataaaaaaag atatactaaa actcaataaa aaagactcat gttctctata taatgaatct
    79741 attaataata taaataataa ttgtatatca actggattaa aatttttaaa acaagcaaga
    79801 gatttaaacc cagatgatgt tgatatatta aatctcacag gtcttgtaaa cttactaaaa
    79861 tgtaattttg atgatgctgt agaaagtttc tataagagtt cactttgtga aaaaactgct
    79921 ctgtgtgaaa agtatataaa catgcttaca tctgaggagt ttttaatttt ctttgaaaag
    79981 tacaatcaac ttataaggtt aataaataaa ggaatgtata aagaagctat acaagggttt
    80041 aaacttataa ctgaccaata ctgtgattta atagaacctt atgagttgct tgccttactg
    80101 tatgacaagg aagaagaata tataaaattt gatgaatgtt tagaagtatt gaagattatt
    80161 gataaggaaa attatttatt aaatcaagaa aataacacat tatatatgta taatagtgct
    80221 aatatacaaa ctaaaagtaa tataaaagta gatgattata agaatgagtt cttacataaa
    80281 agtagtagta accataaaat taatgattat aatgatgtaa ctaaagaaaa gagttcaagc
    80341 aaaaaccaga aaagttcaga ttctaataag aaaaaaagta ttaaaaaaaa taagtaccta
    80401 tatatagcca taatattagg aatattatta gtaggacaaa gtatatatag ttcttataag
    80461 atgaataatt taactgataa aatatctaaa aataatgaaa ctaaaaatga agagtcaata
    80521 gattctaact tgactaagaa agaaaataat atagaagaaa atgaagatat gagtaaggct
    80581 tctaatataa ataagagtaa taaaaacatt aataaagagg atgatgtaaa atctaaaaaa
    80641 aatactgtag aaaatgaaga tgataaagat tctgacttat ttacagagga tgaattgatg
    80701 tctaaggcga atactttaaa atcagaaaag aaaactaaat cttctataca actatataag
    80761 aaagttgcag atataggtga aaataaaggg aatacatctg aagcaactta tcaagttgct
    80821 attctcagtg aaaagttaaa agactataaa actgctgaag aatattataa aatgtatgta
    80881 gaaaattact cagaaaaaga tgcttatttt gatgaatctt attataattt aggtatgatg
    80941 tactataaca atggtgattt aaaaaattct aaattgacat taaagaagtt ggttaataag
    81001 gtaccaaata gtatgtataa taattcaaaa gtaaaagaaa ttttaaaaga agaatagtta
    81061 aattagataa gaaaaataaa ttattttatt ttaaaataat atgattataa tatattgaca
    81121 taccatttta aaaaatttaa aatattaatt ataaaatgag gagggataaa aaatggaatt
    81181 tgaaaaaggg agtatttcaa ttcatacaga aaatattttt cctataatta aaaaatggtt
    81241 atactctgat aaagacatat ttataagaga gcttataagt aatggatgtg atgcagtaag
    81301 taaacataaa agacttgtat cactaggaga aatatcagaa aataagtcat cagattataa
    81361 aattacagta tctgtaaata aaggagaagg tacacttaaa tttattgaca atggaattgg
    81421 tatgactgaa gaagagataa aaaaatacat aaatcaagtt gctttttcag gtgctgaaga
    81481 tttctttaat aaatataagg ataaaatgga agagtcaaat gatataatag gtcattttgg
    81541 attaggattt tattctgcat ttatggtgtc taaaaaggta caaatagata cactttcata
    81601 tacagaagga gcgactcctg taagatggat atctgaaggt ggtacagaat acgaaatatc
    81661 tgaatcagat gctagaaatg atagaggaac tactataaca ctatttattg atgatgatag
    81721 taaagaattt ttagatgaat ttactgtaag aggaataata aataaatact gttctttctt
    81781 accagtagaa atatatttag aagatgttga aagattagaa agagaagcta aagaagcaga
    81841 agaaaaagct aaaaaacaaa aggaagatgg aaaagaagag attgtagatg caaaagtaat
    81901 tgagccttta aacgacacta atcctctatg gttaaaatct ccaaaagact gtactgatga
    81961 ggagtataaa gagttttata gaaaggtatt caatgtattt gatgaacctt tattttggat
    82021 acatttaaat gtagattatc ctttcaattt aaagggtata ctttacttcc ctaaattaaa
    82081 aaatgagttt gaactgactg aaggaaaagt aaaattatac aacaatcaag tgtttgtggc
    82141 tgacaatata aaagaagtta taccagaatt tttactttta ttaaaaggag ttatagactg
    82201 cccagactta ccattaaatg tatcaagaag tttcttacaa aatgacaggg atgtaagcaa
    82261 aatttctaaa catataatta aaaaagtagc tgataagttg aaatctcttt gtaaaaatga
    82321 aagagaagaa tacaataagt tttgggatga tatacaaata tttattaaat atggttgctt
    82381 aaaagatgaa agtttctatg agaaggtaaa agaatgtata ttattcaaaa ctattgatga
    82441 tgagtatata acattacaag attatttaga aaaatgtaag gacaaacatg aaaataaggt
    82501 attttatgta agtgataagg aacagcaatc tcaatacatt aaactattta aagaatacga
    82561 cttaagtgct gttgttttaa actcatcaat agatactcat tttatttcat ttatggaata
    82621 taaagagaat ggagttaagt ttaatagaat agatgcagac ctttctgatg tattaaaaga
    82681 taaaaatgaa aataaagata gtgaagaaaa caaagaagag atagctaaga tagaaggtct
    82741 gtttaaagaa gctgtcggag aaagagtgaa gaattattct gtagaaggat tgaaaaatga
    82801 agacactcca gctatggtat tagtatcaga acaatctatt agaatggcag aaatgcagtc
    82861 aagatttgct ggaatggatt taggaatgaa ttttgaggaa gaaaaaactc ttgtaataaa
    82921 tgagaacagt ccaataatca aaaaattggt ttctcttaaa gatgatgagg aaaagaaaga
    82981 taagattacg cttatttgta accagatagc agatttagct ttactttcta ataaagaatt
    83041 aaagccagat gagttagatt catttgtaca aagaagtaat aagcttatga gtcttttgat
    83101 agaattataa gattgaattt gaatacattg aagcaaattt ataaaaagta ttcaatatca
    83161 gtgataagaa agaagtgtct caaaatgaac ttttcagttc atgaggcgct ttttttatgt
    83221 gaaattaaat ttattttaat catttcaaca atgaaaaata tatttatctc tattttgaga
    83281 cagaccattc tttatttttt tatctttggt taattttaaa tatttaagta ggttctaata
    83341 aaaaactcta tttagttaaa tatagttaac ttgatatata ataagataat acatataatt
    83401 aagtaaaaga ttgtttttta gtttatgttt aaatacataa ttacactttg ttaaaaacat
    83461 aaaattatta ctaaagtaga aataggaggt tttagaatga attttaatta taatttgcca
    83521 gtaaatatct tatttgggag aggcagaatt aatgatgtgg gaaaagaagt atctaaatat
    83581 ggcaaaaaag tattgatagt aacaggtaaa aatagtacaa agaaaactgg attacttgat
    83641 aaaacaatag atttactaaa agactctaaa atagaatatg aagtttttga tagagtagaa
    83701 caaaatcctc ttataactac tatatattca ggagtagaaa ttataaaatc aactggatgt
    83761 gattgtgttt taggtcttgg tggtggaagc attatggatg ctgccaagag tatagctttt
    83821 tcttataaaa acccaggaga tttaaatgat tatatatttg gaattagaca aggtgaagaa
    83881 gctttaccta taatcttagt tccaacaaca tcaggtacag gtagtgaagg aaattgtttt
    83941 gcagtactta caaattcaga aactaaagat aaaaaatcta taaagaagaa tagtatgtat
    84001 gcaaaagcat caataattga cccagaactt atggttacaa tgccaaaaca tataattgca
    84061 tcagttggat ttgatgcact tgcccataat atggaagcat atctttctaa tggaagaaac
    84121 cctcttgcag atgtacaagc tatttatggg attgaactta tatcagaaaa cctaataaag
    84181 gtatataatg atgttaatga tttagaagca tgggaaaaaa taacacttgc aagtactatt
    84241 ggaggaatga cgattggtac agcgggtaca gccttgccac atggaatgga gcatcctgta
    84301 agtggtctta gagatgtaat gcatggaaaa ggacttgcag ctttgactcc tactattata
    84361 gaaagttcat gggatagtga tattgaaaga tttggtaata tttcaaaggt attaggagga
    84421 acttgtgcag aagattgttc agatgcaatt agaaatttcc ttaaaaaaat agatttagat
    84481 ataaaactaa gtgatttagg tattgaaaaa tcagatatag attggttaac tgataattgt
    84541 atgaaaatat cagttgcaaa tattaagaga catccaaagt attttaataa ggaacaaata
    84601 aaggaaatgt accataagtc tttataattt gactttacat atttagtttt atataaaaat
    84661 tataaattaa taataaaaaa ttataagtaa ttaatagtaa aaaaattgtg tatagaagtt
    84721 atatatataa taaatttgtc ttaagctttt attttacttt ctaataaata aaggagttta
    84781 aaaaagggaa gattaattaa gtaatatttt ataaaattct tcgatttaaa aactttaagt
    84841 agaggtgaaa taaatgttta atcccaaaag aataatattc gaaaaaggaa ctttagacac
    84901 tgatgtgggt aaaaaaatat acaataaatt tagagataat aaagatgtag agataattaa
    84961 tatatcatca aataggatta aagaacatat tccaggtgaa aatctatatg aacaatatag
    85021 aagtgggaag cagactatgg tagttgggat tagaaaaagt ctgaagtttc aaacatgtaa
    85081 accttctgct aattatcaac taccacttgt cagtggatgt atgggaagat gtgagtattg
    85141 ttatttgaac acacaattag gtgataaacc atttataagg gtgtttgtaa atgtagatga
    85201 aatacttgaa cagacaaaaa aatatattga agatagaaag ccacaggtaa ccatatttga
    85261 aggggcagct acatcagacc cagttccagt agagccatat actaattctt taaagaaaac
    85321 aatagagttt tttggaagag aggaaaaagg aagatttaga tttgttacta aatacagtga
    85381 tgtggatagc ttattggatg ctgaacataa taatcataca gaaatacgat ttagtatcaa
    85441 tactcctaga attataaatg aacatgagca ttatacagcc tctgcaaata aaagaataga
    85501 gtcagctgta aaacttgcta gggctggtta tcagattggt ttcataatag cacctgtgtt
    85561 tttatatgaa ggttggaaag aagagtataa aaatctgatt ataagtataa aagaagcttt
    85621 accaaaggat tttgataaaa aaattatatt tgaagttata tctcatagat atacaactaa
    85681 agcaaaaaat agaatactag agatttatcc agatacacta ttgccaatgg aaaatgagga
    85741 tagaaagttt aaatacggtc aatttggata tggtaagtac gtgtatgata aagaacaatt
    85801 agatgatatg aaagagttct ttcttaagga aataaatgga gtatttaaaa atagtttaat
    85861 aaaatatata atatagcaaa tcttacctaa agatttgcta tattttattt ttatacattt
    85921 tatgtttata ataaagcaat gagatttagc actatcatat aagaaaatta aaaagggcac
    85981 tatctatcaa gaacattttt tctagttttg atactataaa ggataagagt aacaaaaata
    86041 tcaggaggag ttatagtatg catgcatggg agtctattca aattacattg gatttaatag
    86101 aagcaaattt atcagaagaa atatcaatta atgaattagc aaataaagca aatttatcac
    86161 cattttacta tcaaagacta tttaaaagat tggtaaataa gactgtaatg gagtatataa
    86221 agcttcgtcg tcttgcaaga gcttctgaat acttagcaga acataagaat cgtatacttg
    86281 atgtagcttt aaattttgga tttgctagtc atgagacatt tacacgttcc tttaaaaaag
    86341 catatggatt aactccagaa aaatatagag caaatccagt aaaactcaat cactttatta
    86401 agccagaatt aattttaaat tatgctatgg ttgatgaagg tgttccactg attgcagatg
    86461 atatagtgat tgaagtcaat cgtaagacat tgagtaatcc aaggacattt gttggaatag
    86521 aaatagaagt acctatttgc cagttggtgg gcggtgaaac aactggaatt gcaatagtag
    86581 aggaattatg gatgaaactt ggaagtcaaa gacataatat accaaatcaa attccaggtg
    86641 gaaatgaatt tgctgctctt tatatgggaa atgcaaaaga aggaaattgt atgtatatgg
    86701 caggtgtaga ggtagagtca ggtacatcag tagaaggata tagtactttt gagttgccag
    86761 ctaaagaata tttagtatgt ggatttgagg cagaaaactt taatgagtta gttaattcag
    86821 ctgtttttaa agcagataaa tttatggaaa gatggatgaa gaaacataat ttaacaacta
    86881 ctgattttgc aattgagatg tattacccca ctacacctga agcagcatat ctggaacatt
    86941 ggattgttcc ggttcctatt gaacaataga aaggatgatg aatatgaatt ggcaagatgc
    87001 gttttttcaa gatactaaac ctacatttga gcaaattaat gaatttatta ataatccatt
    87061 atgggacaag ttaaataaaa ctttggtttc tacttataat gtagaaccta agcttgaata
    87121 cagtaaatgt tcaatgcaaa gaggttggaa tgtaaaatat aaaaaaagag gtaaatcact
    87181 atgtacttta tatccacaag aaggttattt taaagctttg gttattgtaa gtgaaagcaa
    87241 tagagtagag gttgatttat ttattaatac ttgttgtgat tatatcaaaa aaatatataa
    87301 tgaggtaaac ttttttaatg gaagtaaatg gctaatgatt caagtagata gtttattggt
    87361 attaaacgat atgcttgaac taattaaatt tagagcttaa catatagaac aggatgaata
    87421 tataagtcat cctgttttta tattcaatca gataaattaa tatatagtct ataatatgaa
    87481 taatttagta aatttaaatt tactttatct ttctacattc tttgcaacta agtccacatg
    87541 tgtttttttc ttgcatatta gtagcacccc aattagcaaa ttgttgtaaa ataggcacaa
    87601 tacttttacc tttacttgtt aatgtatatt caacttttgg aggaatttca ttatattgtt
    87661 tacgatgaac aataccagta gactctaaat cttttaatga ttgagctagc atagtatttg
    87721 taatgccatc caattttctt tttatgctac tatatctaat tggattttca actgctaaca
    87781 tacatataat aggtaatttc cacttaccac cgacaatgtc taatgcataa cggattggac
    87841 aggttaattc ttcaacgttt ttagttatat ttttttcagt atttatactc attttaatta
    87901 ctccttagtt atagtagtat cttttttata ctttatcaga aaaaactgca tacttgtttt
    87961 ttctgtattt tatattaaaa ttatatcaaa ggataatcct taatacaagt atttaaaagg
    88021 ggtgtaagaa ttatgaaagc attagaattt ttgaacaagg cacgagttta ttatttagca
    88081 acagttgatg agaacaatca agcacatgtg cgtcctttag gatttgttat ggaatacaat
    88141 ggtaaactta cattttgcac atctaatcaa aaggatatgt ttaagcaact tatttttaat
    88201 ccaaaggttg aactttgttg tatagaccaa aaccttaata ctctacgtat tttaggtgaa
    88261 gcagtatttg ttacatcaaa agaaacacaa gctaaggcac ttgaaataat gccaagttta
    88321 ggtcagatgt actctgtagg agatggtaag tttgaaatat tctctattga taaggcaaaa
    88381 gttagttgtt gttcaatgag tggtaaaaag attgatgtag agctttaatt ataattgaat
    88441 cgacatccat agtgaaaatt aagaaaacgt tattactgaa atgttgatag atttaattta
    88501 aatgcaataa aaagattttt aaataatgaa tatgtaaaaa tttttagtta ttagatgtgt
    88561 atttcaataa tgatata
//
LOCUS       DAMJVG010000005        78303 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.005, whole genome shotgun sequence.
ACCESSION   DAMJVG010000005 DAMJVG010000000
VERSION     DAMJVG010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 78303)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 78303)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..78303
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.005"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            32..1312
                     /locus_tag="PC512_000400"
     CDS             32..1312
                     /locus_tag="PC512_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HDF2440179.1"
                     /translation="MNILGLIVEYNPFHNGHIYHLSKSIEKTNATHTVAIMSGNFLQR
                     GEPALFDKYTRAKIAVENGVDLVIELPTLFACQSAEIFSHGAITILNSLNCINSICFG
                     SEEGNTEILYNIAEILANEPNEFKLLLKKYLDDGLLFPTARANALFDYIHQDKKNNFI
                     QNYSKEQLSKTLNSSNNILGIEYIKNLIHLNSSIKPFTISRVQSEYNSEEIESDICSA
                     TAIRTSLKENTDLFHLKNVIPEKTYNILNEKIDNGFLPMFDDFFFDILKTIILRDMDT
                     LKEYFEVNEGIENRIYKDIFTSEFLHELQLAIKSKRYTLTKIKRTLNNILLGIKKSDM
                     QLIKNIDTIPYIRILAFNDKGREILKEIKNKSEIKIINKFSNISFSLDDTIFKTLISY
                     DIKATNIYNSIYYKNNKDLVKGPMDFYTHPIYVK"
     gene            complement(1575..2966)
                     /locus_tag="PC512_000401"
     CDS             complement(1575..2966)
                     /locus_tag="PC512_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HDF2440180.1"
                     /translation="MYKLIDKKDIDFLIDTCGEENVLVGSDINEDFSHDELGGIEKYP
                     EVLVNVLETEQVSKIMKYAYKNNIPVTPRGQGTGLVGAAVAINGGIMINLCKMNKILE
                     VDYENLTLTVEPGVLLMTIGQYVQDRDLFYPPDPGEKSATIAGNINTNAGGMRAVKYG
                     VTRDYVRGLEVVLPNGEIINVGGKVVKNSSGYSIKDLLVGSEGTLGIVTKAILKLLPL
                     PKKSISLLIPFPDLSMAIETVPKIIKSKSIPTAIEFMERDVILAAEEFLGKKFPDNTS
                     DAYLLLTFDGNSTEDIEKEYEKVANLCLENGALDVFISDTQERNDSIWSARGAFLEAI
                     KASTTQMDECDVVVPRDKIAEFIRYTHELQDKLKIRIKSFGHAGDGNLHIYILKDGMD
                     DNTWKIRLKETFDYMYKKSRELSGQVSGEHGIGYAKKEYLHESNSDAYMMLIKNIKLA
                     FDPKNILNPGKIY"
     gene            complement(2977..4197)
                     /locus_tag="PC512_000402"
     CDS             complement(2977..4197)
                     /locus_tag="PC512_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding protein"
                     /protein_id="HDF2440181.1"
                     /translation="MSKIVVNQDKITDLKRILEICPFGAIEEKSGIVEISAGCKMCKL
                     CVKSGPKGAFEFIESSKVQINKDEWRGIAVYVEHHNGNIHPVTYELIGKAREMASKIK
                     QPVYCVFVGKDIKDKCSNLISYGVDEVFVYDEDEFKDFRIEPYSKAIENFIDKIKPTI
                     VLVGGTTLGRSLAPRLAARFRTGLTADCTILDIQSNTDLDQIRPAFGGNIMAHINTPN
                     NRPQFATVRYKIFSAPEKIENTTGKITLCKVEKKELKSKIKVLSVKEKNKEVGLEEAE
                     VIVVASRAIKKQEDMEMIYKLADKLNAQVAGTRPVIEAGWIDAKKQIGLSGRTVKPKL
                     IITCGVSGAVQFVAGMQGADYIVAINKDDKAPILDVAHLALIGDIYDIIPKLIEKIEN
                     NKDNNQKYMASAAK"
     gene            complement(4211..4999)
                     /locus_tag="PC512_000403"
     CDS             complement(4211..4999)
                     /locus_tag="PC512_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003402402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HDF2440182.1"
                     /translation="MEILTCIKQVPGTTSVEVDETTGVLKRDGVDSKMNPYDLYALET
                     ALRIKEDKKANLKVLSMGPPQAKKVIEESFMMGADEGALISDRRFGGADVLATSYTIS
                     QGIKKMGKVDLIICGKQTTDGDTAQVGPEVAEFLDIPHVTNVTKLIEVKDESIVVEID
                     MPNDLQVCEIEYPCLITVEKDIFQPRLPSFKLKLNTKDREIPVYSLDDFEDKNENNYG
                     LNGSPTQVVRIFPPKPNTDKNIVRENADELSFALVNKLEELKLV"
     gene            complement(5016..6290)
                     /gene="larA"
                     /locus_tag="PC512_000404"
     CDS             complement(5016..6290)
                     /gene="larA"
                     /locus_tag="PC512_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel-dependent lactate racemase"
                     /protein_id="HDF2440183.1"
                     /translation="MVKLKVPYSKQGMILEIPDERFLGVLESKSDNYIEHKTQEEIVE
                     ESMNNPIGSNSLEELVKGKKNVVIITSDHTRPVPSRITMPIILRRIRNVNPEIDVKII
                     VATGFHRPSTREELIYKMGEEIVDNEDIVMHISTDDKSMCKVGILPSGGDLYINKLAY
                     EAELLIAEGFIEPHFFAGFSGGRKSVLPGIASAKTIMYNHCSDFIDSDNSRTGKLNNN
                     PIHEDMVYAAKVAKLAFILNVVIDKDKKIIASFAGDVEKAHTKGCRFVTELSKVNSIK
                     SDIVVTTNGGYPLDQNIYQSVKGMTAAEATCKDGGVIIMISACNDGHGGQSFYENVAN
                     ADSPKQLLDKIRSVDRVDTIPDQWEFQILARILSKYTVIMVTDKCNPEMIKKMHMKHA
                     FNFKEALEMANSIVGKESKVVVIPDGVSVIVK"
     gene            complement(6408..7121)
                     /locus_tag="PC512_000405"
     CDS             complement(6408..7121)
                     /locus_tag="PC512_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HDF2440184.1"
                     /translation="MFNSIASKKVYEQVIEQIQYKILNGELKKGDKLLSERELSEQMN
                     VSRTSIREAIRVLETMGVIESRQGEGNFICTNIEKTLIEPLSMIFKLNNGTLEDILEL
                     RIILEIEIAKLASKRITSSEVIELKHIIDEMRVETNKKDNNRVLVLLDQKFHSKLATL
                     SKNYLIQSLFMTASKLFDGFIEDAREKIIAEPFNENILLKQHEAIYNAVVENDVELAC
                     EKAKEHMDFISKNYRKNEN"
     gene            7246..8505
                     /locus_tag="PC512_000406"
     CDS             7246..8505
                     /locus_tag="PC512_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YlbJ"
                     /protein_id="HDF2440185.1"
                     /translation="MKKNKIIAFFAPSIIVGVLVLGIILYPNEAIKSAREGFSIWSNV
                     LVPSLLPFIIGANLIVDLKIVDIIGFIINPITRFVFNVSGKSALAFAISTVSGYPVGV
                     SLASEFRSNGQISKYEAQRLVSFCSTSGPLFIIGSVGTGMFQNSNLGYLMILCHYLGT
                     ILVGLFFRNYGNENLPKTKLDLKTNIKNVINIRNSSGNGFFVLFGNAVFNGVNTLLTV
                     GGFVIVFSVVFKILSLFNVISLIASVIYLPLSFLGVSKELCQAFVSGLFEITIGCNKV
                     SSITSSPEILRASLASFLIGFSGLSILAQCCTFLSKTDIDLKLYILSKFAHGVLAAIF
                     IFILYPIANSAVLVSSFADTYNVIYNNLIWFYYLSYYDTILQIVVIIYLISAVFIAKK
                     HMKTLSTNGKLMRYKNTFFTKKFSRKK"
     gene            8785..9351
                     /locus_tag="PC512_000407"
     CDS             8785..9351
                     /locus_tag="PC512_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDF2440186.1"
                     /translation="MATRPIEIDEYKKIMELLHTGFTYSENGVEKRFRKNPKVALALM
                     LEANLGLRISDILRLKIGNFKGNMLEINEKKTGKLQYRPVNKNIIESINEHARKYNLK
                     SNDYLVNIKTKAIQKQLRIICKHLNLYNISTHSFRKLYATTQFEKSNNNLELVKELLN
                     HSSVATTQRYIRVTQQAINEASENFFIG"
     gene            complement(9552..10757)
                     /locus_tag="PC512_000408"
     CDS             complement(9552..10757)
                     /locus_tag="PC512_000408"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HDF2440187.1"
                     /translation="MKIAILGYGTVGSGLIDLIENNTSKRDIEVVGILVKNKEKHKYK
                     KYFDKITTDIEDIFDKDIDILVEVIGGLNPAFDYVTRALNKKIHVVTANKDLLAEKGS
                     DLIELANLNNVSIKFEASVAGGIPVLKPLIESLEGNNIKSINAILNGTCNFILSKMYD
                     ENLPYDVALKQAQELGFAEVNPDADVLGYDSARKLSILSTLSYGKIVYWKDLLLEGIT
                     SIDEKDIEYAKKLNCKIKLVARSKYESGEVSGFVRPALVDNNNMLSKIDNEFNVVILV
                     GDSVGELSFVGKGAGRGATGSAVYADIIDIIDNRSSNIKSFSKGKLDLSGLIEDECSA
                     VVRFGGYNNKDGILECLDKYVDSYDIIDDEELAIFVSAKSEHEIDRVLEIVKRNNYSE
                     SAKKLLKID"
     regulatory      complement(10860..10966)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(11058..11426)
                     /locus_tag="PC512_000409"
     CDS             complement(11058..11426)
                     /locus_tag="PC512_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhbY family RNA-binding protein"
                     /protein_id="HDF2440188.1"
                     /translation="MLKGKQRAYLRSLANTLKPTTQIGKEGVTESFLEQLDGMLRTRE
                     LVKVTILENAGLDTKETANAVCEALRAEFVQAIGFKFTIYKRNIEEPKILFPGHEQAK
                     AKTKNNNVTKKGKPTKRAVR"
     gene            complement(11478..12755)
                     /gene="obgE"
                     /locus_tag="PC512_000410"
     CDS             complement(11478..12755)
                     /gene="obgE"
                     /locus_tag="PC512_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000469293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HDF2440189.1"
                     /translation="MFIDKARIFVKAGNGGNGSVAFRREKYVPAGGPDGGDGGRGASI
                     IFEVDLGLRTLMDFKYQKKYQAQNGGDGSKGKRAGKNGENLVLKVPAGTVIRDEATGL
                     VLADLKKEGDTAIVAKGGIGGKGNQHFANAVRQAPAFAKSGTDGEERWITLELKMIAD
                     VGLLGFPNVGKSTFLSVVTKAKPKIANYHFTTLTPNLGVVQTKFGDSFVLADIPGIIE
                     GASEGIGLGHEFLRHVERTKVLIHIVDISGLEGRDPIEDFDKINDELKLYNEKLSKRP
                     QVVVANKFDILEDESKFEKFKSELEGRGYTVFKMSAATRQGIDEVIAYVSKMLKEVED
                     VELVSEEEMYRPELDIGTEEELSIDIEDGVYVVTGKALRRIMYSVNFDDMESLQYFQK
                     AMESQGVFDRLREMGIEDGDVVKIYELEFEFYN"
     gene            complement(12866..13156)
                     /gene="rpmA"
                     /locus_tag="PC512_000411"
     CDS             complement(12866..13156)
                     /gene="rpmA"
                     /locus_tag="PC512_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HDF2440190.1"
                     /translation="MLNMNLQLLASKKGVGSSKNGRDSISKRLGVKRFDGQLVTAGSI
                     IVRQRGTKIHPGTNVGKGSDDTLFALVDGTVKFERKDKKRKKVSIYPVAIAE"
     gene            complement(13170..13487)
                     /locus_tag="PC512_000412"
     CDS             complement(13170..13487)
                     /locus_tag="PC512_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HDF2440191.1"
                     /translation="MIKVKYYYNDDFLLQGFCLKGHADFAEIGYDIVCAAVTSNAIAV
                     INSLDKLQKIEFEKVVGEEGHIECIVKDTHVKDAQLLLNHFQLAVKEIKREYPKNIKI
                     LKK"
     gene            complement(13502..13813)
                     /gene="rplU"
                     /locus_tag="PC512_000413"
     CDS             complement(13502..13813)
                     /gene="rplU"
                     /locus_tag="PC512_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012063435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HDF2440192.1"
                     /translation="MYAIVKTGGKQYKVSEGDVLFVEKLEANAGDVVTLNEVLACSKD
                     GELKLGSPVVEGASVQAKVVEQGKAKKVIVFKYKAKKDYRRKQGHRQSYTKIVVEKIN
                     A"
     gene            complement(13914..15335)
                     /locus_tag="PC512_000414"
     CDS             complement(13914..15335)
                     /locus_tag="PC512_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rne/Rng family ribonuclease"
                     /protein_id="HDF2440193.1"
                     /translation="MKKIVIESLIGSQKTAVLEDERLTELFVEDNLNKKTVSNIYRGI
                     VKKVIPGIEACFVDIGFKKLAYLQLKKGSTIKSGQDILVQINKEEIGTKGAKLNTEIS
                     ISGRYIVYIPSNDRTTISNKITDEKERFRLKKITKAVNKENLGLIIRTEAQGCTHDEI
                     KKDIEELKLKYENILKEYKLGIGPKLLYKSLDFATKYVKDNVNDDIESIITNSYDKYS
                     ELKSILRGIDKTYVDKLCLEENRDVFDLYRIESKIEKLLNKKVWLKSGGYLIIEKTEA
                     LTVIDVNTGKFIGTGKLDETVYKTNLEAAKEIVRQLRIRDIAGIIIIDFIDMHKKKHQ
                     KEILHILEEEFNKDKRKAEVLGMTKLGLVEVARRREKESIDKYYLMSCPCCDGEQTIK
                     SVHYILDSIEKEIMRISEHTVYKNIMVEFNDFIFEQIKEYYMDIIDKIGEKYNIKISL
                     NANSTLKHNKTNVIFDKIVDNKM"
     gene            complement(15353..16054)
                     /locus_tag="PC512_000415"
     CDS             complement(15353..16054)
                     /locus_tag="PC512_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2344 domain-containing protein"
                     /protein_id="HDF2440194.1"
                     /translation="MSKIIRVKFKKEGDMIYISHLDLQRLLQRAFRRAEINLSHSQGF
                     NPHPKMSYGNALALGTESQGEYVDIEIEEDDLSVEEFLNKVSIQLPDGIDFIKAKEID
                     RQTPSLSSVIDYGEYLFNIDLKRPMTKEFVKRKVIDFMNNKEIIITKKNKKGKMVEVD
                     IRPMIRTFDVLNLEDEHITLTATIATGSKTNLNTNILIPKILEMFELDIDPLDVDILR
                     RDLYVLEDGELVTPM"
     gene            complement(16056..17900)
                     /locus_tag="PC512_000416"
     CDS             complement(16056..17900)
                     /locus_tag="PC512_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03960 family B12-binding radical SAM
                     protein"
                     /protein_id="HDF2440195.1"
                     /translation="MNKVDLKKILKKVEKPARYLGNEINSIHKDTSNSELIRYAHCFP
                     DLYEVGMSHLGSHILYDVINKDEDVFCERVYSPAVDMENIMREKSIPLFALESREPIT
                     NFDFVTFTLQYELSYTNILNILDLANIPILKEERTLEDPFIMVGGPCAYNSEPLADFV
                     DVVILGEGEEVNLEVVNEYKEWKKNKTTREDFLYKISSIEGVYIPSFYDVKYNEDGTV
                     QSVTPNREGITKNPTKRIIKDVETVDYPEKLIVPYIDTVHDRIVLELFRGCTRGCRFC
                     QAGMIYRPIREKSVKRLKEILDKLVKNTGYDEISLSSLSTSDYSKLSELTDYLVDEYA
                     SNNIGISLPSLRLDNFSMEIADKIQQVRKSGLTFAPEAGTQRLRDVINKGVTEEDLEN
                     ATERAFEMGWNSVKLYFMIGLPTETYEDLDGIAKLAYKVIDIYRKVNGGKLKRSFSVT
                     VSTSTFVPKPFTPFQWHGQDTTEEVINKQRHLVNKLRNNNIKYNYHDSKTSLMEAVVA
                     RGDRRIGKVIYDAFRLGAKFDGWAEHFNLDIWKEAMEKNNLSIDFYAHRNRNYEEVFP
                     WDHIDVGISKKFLIREDENAKKEKITSDCRHNCNGCGINIHDIGRGLC"
     gene            18219..19412
                     /locus_tag="PC512_000417"
     CDS             18219..19412
                     /locus_tag="PC512_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FprA family A-type flavoprotein"
                     /protein_id="HDF2440196.1"
                     /translation="MSKVFEVKKDIYFTGVVDEGLKVFDIIMETEFGTTYNSYLIKDE
                     KTVLFDTVKANFKDEFLSNLSEVTDIAKIDYVVIHHTEPDHAGSLKYLLDINPNIEVY
                     CTKAAKLYLDGQINRPFNCHVIKDGEILNIGKRNLRFITAPFLHWVDTMFTYIEEDKT
                     LLTCDAFGCHFASVDAEVVNSEDYLKSAKHYYDCIVKPFAKHVLSAVDKVVGLNIEFD
                     TILTSHGPMLTKDPMAAVKRYVEWSTEAVNTTNQNQVSIFYLSAYSNTLEMAKKIKEG
                     LDKEGAKAELYDLEDMTLTEMHDTLVVSKVILLGSPTINKTMVKPMWDLFSVIDPMAN
                     QGKIAGVFGSFGWSGEGITMAETLLKSMSFKMPVESLKKKFFPSEETLKECMAFGAEF
                     AKLVK"
     gene            complement(19624..20706)
                     /locus_tag="PC512_000418"
     CDS             complement(19624..20706)
                     /locus_tag="PC512_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HDF2440197.1"
                     /translation="MKKIRKLATKLLIAMMVLTSCMSVTVYGMTAKDVTAKTPKSYVA
                     GTNSIYGPKLSQAQLNSVAQATADFMNKKITKNMTTDAKIRVAYNHIKNNTTYVNWNA
                     AEGANTAYTLVTKKGACSGMCRSLKALCDAMGIECYYVHSTTNDHQWNLIRFEDGRLY
                     HVDIDANKSAGADIIYKSLTHPLPFDKKAYPAVGEVVKTQNPTPTVKKPTPAKPSAPV
                     GPGNHTMIADQQGAILDEVYGNNLRPKIEMYEGVPCSLINSSINTIKFTSKNSNLDPS
                     KHTVTVIGFMNTPYGMVALAPDGVPDEYPFEYDKPFSLDFTGKNLSAAELSKKCKENN
                     VIIKVEIGETASNSGRGMVAYARYVN"
     gene            complement(21270..22061)
                     /locus_tag="PC512_000419"
     CDS             complement(21270..22061)
                     /locus_tag="PC512_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440198.1"
                     /translation="MKLIDEYLDKLYKKCDNKSTIELKQEMRCHLIESANEFKLEGLD
                     EEEACKKAIERFDDGDEMQYELCNIIKELSLSLDRHKSIVMGFKKVLGYISIIAFLIS
                     GFMWYYNNSLQHNMYNLGKELDGEIKQLAERHDMTKIGEYKLELEKILDKDKYSKVKA
                     LRLYVIDMKDGNTNLSSSGLNANMVYEREADYNNISNFIQHLGYNGKDFLDKNGNIVN
                     PDIFLEYFFYFESEMLIPVAFAFGLLCIIAYFILRFKISLIKNNN"
     gene            complement(22065..22394)
                     /locus_tag="PC512_000420"
     CDS             complement(22065..22394)
                     /locus_tag="PC512_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2440199.1"
                     /translation="MQLNKEVLKGYIDILIVSILEKKDCYGYEIAKQVRERSEFELKE
                     GTMYLALKRMESKNLIKSYYSNEQSSGGRRKYYNLTNEGKDFLEIKKQEWRFIKKVMN
                     QFLGEVD"
     gene            complement(22879..23292)
                     /locus_tag="PC512_000421"
     CDS             complement(22879..23292)
                     /locus_tag="PC512_000421"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HDF2440200.1"
                     /translation="MNIALVAHDQMKNTMVGFCIGYESILKKYGLYATGTTGKRIMDE
                     TELNINRLASGPLGGDQQIGSLIVTQEIDLVIFLRDPLTSQAHETDIQALIRLCDVYH
                     VPIATNLASAEIFIKALDRGELSWREVRKSKSQRI"
     gene            complement(23333..24463)
                     /gene="rodA"
                     /locus_tag="PC512_000422"
     CDS             complement(23333..24463)
                     /gene="rodA"
                     /locus_tag="PC512_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein RodA"
                     /protein_id="HDF2440201.1"
                     /translation="MKKININYKSTIKLIKQLDWKLIVTVLAIFIFGLVILSSATHAN
                     STGSYNQLIKQGLAFVLGIGMIIVILFFDYNLLGRYYKALYIISLILLAIVLLPGIGT
                     VKGGARSWINLGPLDLQTSEIVKLTFVLSYAKILESKKDKLNTLKEVMPVVVYSLPFI
                     GLLIAQPDLGTGIVFCCMIFAMLFTAGLSSKLIKRGIIILLVSMPLMYLMMADHQKVR
                     IEAFLNPEDVTLKGNYQVMQSLIAIGSGGVTGKGLYNGSQNQEDFLPVQDSDFIFAVV
                     GEELGVIGMAVLIILFMIFLLRLLAIARDAKDFYGTLIVVGVMGMFGYQIIQNIGMTV
                     ALIPVTGVTLPFVSYGGSSLLTSLANLGLVLNVCMRRKKINF"
     gene            complement(24548..24832)
                     /gene="minE"
                     /locus_tag="PC512_000423"
     CDS             complement(24548..24832)
                     /gene="minE"
                     /locus_tag="PC512_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division topological specificity factor
                     MinE"
                     /protein_id="HDF2440202.1"
                     /translation="MLDLFRVFSNEAKTSKSVAKERLKLVLVHDRVDCSPQLLEMIKT
                     DILKVIANYAEIEDDGLEIKMSKCRGEHDDKPVSALVANIPLKNIKDRCM"
     gene            complement(24850..25647)
                     /gene="minD"
                     /locus_tag="PC512_000424"
     CDS             complement(24850..25647)
                     /gene="minD"
                     /locus_tag="PC512_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinD"
                     /protein_id="HDF2440203.1"
                     /translation="MSEVIVITSGKGGVGKTTTAANLGTALSLENKKTVVVDADIGLR
                     NLDVVMGLENRIVYDIVDVVEGTCRLKQALIKDKRFDNLYLLPAAQTRDKNAVSVEQM
                     IDLCEKLKESFEYIIIDCPAGIEQGFKNAVAGADRAIVVTNPEISAVRDADRIIGLLE
                     ANEIKEIRLVINRIRNDMVKRGDMMDKQDIIEILAIDLLGLVPDDESIIISTNKGEPA
                     ILDSKSLAGQAYKNIAKRILNEEVPLLDLEVEDGFFGRLKKMFSMAK"
     gene            complement(25671..26354)
                     /locus_tag="PC512_000425"
     CDS             complement(25671..26354)
                     /locus_tag="PC512_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinC"
                     /protein_id="HDF2440204.1"
                     /translation="MSLREICSQELVEFKGNKRGIIVNIKREAPFEEIQEKIINKLEA
                     YVGFFNGAKISKINSDCLTDMEILELKEGITSRFDVEFVEDQKIEENSNFPTKYVNTL
                     RSGENIEFEGDVVILNDMKPGSKVLSKSNTVVMGDINAGAKVVAGGNVFVMGKIEGFV
                     HAGAEGNEFAYVVAGNLNPKILQIADNIAEAPDDEENYESESEISPEIAFVSNGRIVI
                     ESYLSKLDK"
     gene            complement(26452..29430)
                     /locus_tag="PC512_000426"
     CDS             complement(26452..29430)
                     /locus_tag="PC512_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HDF2440205.1"
                     /translation="MEENKQVDRLKIIKIVMGVIFLAILVKIIYMTTFKYEYYNELAE
                     NKTYKKLAIEAPRGEIKDRYGRLLAGNKNLFTVQVSGNDINKKDANKHSRANEISLKL
                     INLLERNGEEYVDEFPIYVENGKYYYTYDRDIREYKSENGIPNDYNAKESFYYLVDKL
                     ISAGILSQEDKRLDATRLQAKLNENGYYPPILVSKWMFTAERDKRDWLASYKIKETKL
                     SAKEAFEKVRNSDALEIDKSLSDEDARKIMVVRDLIKSKGYSQYNPVTIAKDVGETTI
                     AQIEESAMDLVGVSIAVEPVRYYPNGSLASHMLGYVGKMPSTQIESYLQKGYETGDMV
                     GLAGVEKSNESRLRGTDGYKMVKVDALGRISKEIESKKPKSGDTVYLTLDKDLQEVSD
                     NALKQIIEVASKGGTFKSKFGDKPISAYAGKAQSAALIAIDVKNGEVLASSSYPNYDP
                     NKFAKGISTEDYKALQPKNPNDLLAGSPLLNLVTQGEFQPGSSFKMVTSMAALENGLD
                     PNFTINDPGVIMLGKKSFGDYVWNHGRGNHGMTNLYKAIQESCNIYMATIGTGKTWPD
                     GKSIGIDMNANKILEYAKLFGLDQNTGLQDEVEERAGKVPSTEDKLKSTQALLKSNLE
                     REMANDFVDITREKNPKEYEKRINEIVSWAAEKKTPGRVETMNRLKKLDVKEDRIEEV
                     ADLAVFSYFNFAKWSTADTFNLAIGQGENAYTPAQISRYVAAIANGGNLVELSVVDRA
                     VSSDYSSVKINDQKKVEKIPFKNPDNLKELTKGMKLVARQGTAKSAFADFPIDVAAKT
                     GTAEKSGKIPTDNEYEYLKSHMSSYNVNLNDAIKLADKMKAEKEKELSLAKEKEIKKK
                     LENKDLKDEERKKLEEELEDGVKVRLEDTDKVNSSYLRKAIKELNPKITDDQIDRFKQ
                     DYGSFTWTVAFAPADDPEIAVVCVIPQGDSSVFSLLPTREVIGTYMGLEPTNSKNDNK
                     TNDVNNSSDENINFESQINR"
     gene            complement(29442..29930)
                     /gene="mreD"
                     /locus_tag="PC512_000427"
     CDS             complement(29442..29930)
                     /gene="mreD"
                     /locus_tag="PC512_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HDF2440206.1"
                     /translation="MKKVLLCLLGIVLMTIENSITNYIDIFGISFNLVLIYVTIISLY
                     LDELEGGIIAAIIGLIKDITVGGIFGVNALILFIIAYAIGYMRDQLYKGSYIITFVLI
                     FIGSLIDSIVNIGTSSIIYQSYNISTLFVKGLLVAPIVNSLIGLVIYRLSKRAVLKLK
                     ED"
     gene            complement(29945..30838)
                     /gene="mreC"
                     /locus_tag="PC512_000428"
     CDS             complement(29945..30838)
                     /gene="mreC"
                     /locus_tag="PC512_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HDF2440207.1"
                     /translation="MALRFDKNKNEKKRINVKVIATGVVAITLIGIVGISIGKFSSGS
                     PVNLGVASDAITSVGKGINDGFSFIKNGFKDVANFKDNSKKVKKLEEENEKLKKNMIA
                     LNAKLDKTESLEELKKTLNFVQEEYKATSISASVVGKNDGNWYESFVIGAGKNSGVKK
                     ESIVMNGSGLVGIVYEVSNNYSKAISLLDSKASVSFKLAKDANAKGTITQNTTLDNKD
                     SYNSKGYLQGYMFDSSYNVIQGDIITTSGLGFFPDGIPIGEVEKVVDDKDKSLKYVVV
                     KPYVDFKNINDVVVIEPRNIG"
     gene            complement(30848..31858)
                     /locus_tag="PC512_000429"
     CDS             complement(30848..31858)
                     /locus_tag="PC512_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein"
                     /protein_id="HDF2440208.1"
                     /translation="MTKDMGIDLGTANTLVYIKGQGIVVREPSVVAIRDDSKEVLAVG
                     EEAKKMIGRTPGNIVAIRPMKDGVIADFDITQSMISYFIQKAADKKGVVSPRIAICVP
                     FGVTEVEKRAIEEAARQAGAKDAFLIEEPMAAAIGAGLKVEEPEGNMVVDIGGGTSEI
                     AVISLGGIVTAKSIRIGGDEFDESIVAYVKKEYNLMIGERTAENVKINIGSTFKDDEE
                     INMQIRGRDLISGLPKTIEICSTEVREALKEPVSSIVDAIKSTLERTPPELASDIMEN
                     GIMLTGGGALLRGLDKLITQETGMSVQIAETPLDCVALGTGKSVEDQEIFEKVLMMNT
                     KN"
     gene            complement(31979..32638)
                     /gene="radC"
                     /locus_tag="PC512_000430"
     CDS             complement(31979..32638)
                     /gene="radC"
                     /locus_tag="PC512_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HDF2440209.1"
                     /translation="MAPEERPREKMLAKGVKSLSNAELLAILLRTGNKNKNAIELANY
                     IINRDIQGIRHLEDMTIEELCNIDGIGLSKSTQIKAALELGSRVASFKPIKYKIRNPW
                     DIQRYYMDSLRYLKKEVFKAVLLNTKNEIISDVDVSIGTLSSSLVHPREVFKEAIRRS
                     ASKIIVMHNHPSGSVEPSREDKNITSRLIKCGEIIGIEIIDHIIIGDGLYFSFKENMI
                     I"
     gene            complement(32683..33267)
                     /gene="maf"
                     /locus_tag="PC512_000431"
     CDS             complement(32683..33267)
                     /gene="maf"
                     /locus_tag="PC512_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HDF2440210.1"
                     /translation="MNIILASASPRRKEILENTNVRFDIIKNEIDEIILEGETPKHLV
                     MRLAFEKSMSVASEHNEDVVIGADTVVVLDNAILGKPKDESCARDMLKRLSGREHQVI
                     TGISLINLCEDKKVIDYVISNVKFKTLSEQDIEDYLKTNESFDKAGAYGIQGYGALLV
                     EEIRGDYFNIVGLPISRLGDLLKKYFSINLFYGV"
     gene            complement(33487..34458)
                     /locus_tag="PC512_000432"
     CDS             complement(33487..34458)
                     /locus_tag="PC512_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit B"
                     /protein_id="HDF2440211.1"
                     /translation="MVILTAVLVLGIMGLIFGIVLDFASKKFAVEVDERVEAILGVLP
                     GANCGGCGFPGCGGLANAIVEGNAPVNGCPVGGADVGAKVGEIMGISAEAGEKQVAKV
                     ICKGTCSSAKDKYEYEGISDCRAANVLNSGAKMCKFGCLGLGTCKDACKFDAISIVDG
                     IAVIDEEKCVNCGKCKEVCPKGIIITKPESQEVVVECNSKEFGKAVKEKCTAGCIGCG
                     MCVKACKFDAIIFEDKIAKIDPNKCVGCMQCVAKCPTKVISGDITKKKKVTIDQELCV
                     GCTVCKKQCKFDAIEGELKEKHKVDADKCVGCHLCMEKCPKKAIKIL"
     gene            complement(34474..35049)
                     /gene="rsxA"
                     /locus_tag="PC512_000433"
     CDS             complement(34474..35049)
                     /gene="rsxA"
                     /locus_tag="PC512_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxA"
                     /protein_id="HDF2440212.1"
                     /translation="MNLILLFLSIVLVNNVITSQFLGICPFLGVSKKVDTAVGMGVAV
                     TFVLTLASIITYFIQILLVKTGTGFLQTIAFILVIASIVQFVEMVIQKMSPSLYQALG
                     VYLPLITTNCAVLGIALVNVQKSYNLVETIINGFGAGAGFTLAIVIFAGIRERLELAD
                     IPEAFKGFPITLISAGLMSIAFLGFTGLIKL"
     gene            complement(35064..35657)
                     /locus_tag="PC512_000434"
     CDS             complement(35064..35657)
                     /locus_tag="PC512_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit E"
                     /protein_id="HDF2440213.1"
                     /translation="MNLAKVFKNGLIDENPTFVQVIGMCPTLAVTTSAINGIGMGLST
                     AAVLICANLVISLIRKITPDKIRIPIFIVVIATFVTIVGMLLKAYVPALDKALGIYIP
                     LIVVNCLILARAESFAFKTGAMPSIVDGVGQGLGFTVALTIIGAVRELLGNGSLFGMT
                     LFGASFQPVLIFILPPGAFLTLGFLFAGFNKLRSKKA"
     gene            complement(35670..36239)
                     /locus_tag="PC512_000435"
     CDS             complement(35670..36239)
                     /locus_tag="PC512_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit G"
                     /protein_id="HDF2440214.1"
                     /translation="MNSMVRLGGTLLAISAIAALALGATNQVTAPVIEQRNIQANNEL
                     RKAVLPEAKEFKEMKEDTYKGLGDGLIAEVYEGLDGSEVVGYTLKAKPSGYGGEIEVM
                     VGISSEGQVTGVDIGNMSETAGLGAKAKDDAFKGQYKGKTAEPLEVAKGSTTADNQIL
                     AISGATITSTAVTTGVNAAIDVFNSALNK"
     gene            complement(36239..37216)
                     /locus_tag="PC512_000436"
     CDS             complement(36239..37216)
                     /locus_tag="PC512_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit D"
                     /protein_id="HDF2440215.1"
                     /translation="MENKLIVSSSPHVRSNEDTSYIMKQVIIALLPAAVAGVYFFRLN
                     ALSAMFFCILGTVGTEFLYQKFTKQKSTIGDFSAVVTGLLLAFNVPASLPWWMCLVGG
                     IFAILVVKMVFGGIGCNFVNPALAARAFLLASFPVAMTAWTQPGVNWIGKNLDAVTTA
                     TPLSFLKNGAAGLADISSNGISLADMMIGNIGGCIGETSAILLLLGGVYLMYKGIINY
                     VIPVFYIATVFILTFLLGGFNITFAIYQLFAGGLMLGGFFMLTDYTTSPMTKKGQIIY
                     AVLAGLITTVIRMYGGYPEGVSYSILLVNCLAPLIDKFVRNRVFGEVAK"
     gene            complement(37239..38576)
                     /gene="rsxC"
                     /locus_tag="PC512_000437"
     CDS             complement(37239..38576)
                     /gene="rsxC"
                     /locus_tag="PC512_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxC"
                     /protein_id="HDF2440216.1"
                     /translation="MKLLTFKGGIHPPYRKEYSNTKALEKAQAPKIVYIPLQQHIGAP
                     AKPIVEVGDEVKFGQKIGEQQGFVSCNVHSSVSGKVIAIEQHEVPGGSAQCVVIENDF
                     KEELHESVQPKGQLEDLSKEDIVGIIKEAGIVGMGGATFPNHVKVSPPPDSKAEVVIL
                     NGAECEPYLTADHRLMVENPEDVVFGLRALMKVLDVKKGFIGIETNKPDAIEAIQNVA
                     KDYSEIEVVGLQVKYPQGAEKQLIYACTGKEVPSGGLPIAAGAVVDNVATAAQIAKSI
                     KTGMPLVERITTITGSCIKEPKNLITKVGTLVSEIIEQCGGFKEDKKIGKVIMGGPMM
                     GIAQYTTEIATNKGSSGILCLDEEESRTPDIQNCLRCGRCTDVCPSFLQPLFISAYSL
                     KDDYDTAEYHRAMDCIECGSCSFICPARRPLLQSIRSAKREIGAKRRKQAAQK"
     gene            complement(38792..39736)
                     /locus_tag="PC512_000438"
     CDS             complement(38792..39736)
                     /locus_tag="PC512_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440217.1"
                     /translation="MNRRKTIYRGFNNNRHKIDLRKYVITIACLCLIGYYSYTKIKDS
                     KILEYVSAKIPFLNNSSDITYKDISDELNSIKKGKKSKSQTNSDDKQETNPEKAVNNT
                     KEPEEVKLATIEGWDMYTIQVAAIDNNDDLKKIQTSLVNNDIPFSVMEKDGVKKIQTY
                     SSFDENDVRKQISSVRKVFPDAFLSHLDAPMLSLEYTSNYAYIESISKELNKLITNFK
                     EESSFWSNAENNVDMEKYNTILTNRKAISQNISKEAEKIDYSEMRLFKDNLIEYVKNV
                     NEKIDTASKAANEEKYSVSKSLLLSSMQEYSMFINSIK"
     gene            complement(39847..41121)
                     /locus_tag="PC512_000439"
     CDS             complement(39847..41121)
                     /locus_tag="PC512_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HDF2440218.1"
                     /translation="MKKAIAALGIGAVAVSVSSINASALEKGTVTASALNIRSGPSSD
                     CDKVAKLYKGKTVEILEKSNGWYKVRVSSSVVGWGSAKYISTSGSSEGTSSQNNPTSS
                     GTTISGNGKVNVSSRLNVRSGAGTNYSLVGKANNGDVVKLLEQSNGWYKIKLSNGVTG
                     WASSQYISKTSEDVGTNNSSNSNSTNNSDKKPSSEESIEGKNGKVTSAVSLNVRSGPG
                     TSYSIIGKLNGGDVVELKAKSNGWYKVKLSSGTIGWVSASYISETNEDTKEKPNSSSN
                     QNSQSNSNSKPSFTGNSDKSTAKGSTIVDFAYTLIGIPYQWGASGPDKFDCSGFTQYV
                     FKHSVGVSIPRVSREQANFGSAISMGNYAPGDLVYFDTDGDGTTNHVGIYVGNSKFIH
                     CSGTQTNPNKVKVDNLTSSYWSKVLLGARRFV"
     gene            complement(41253..41624)
                     /locus_tag="PC512_000440"
     CDS             complement(41253..41624)
                     /locus_tag="PC512_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDF2440219.1"
                     /translation="MKFNFCHNNFNVTNLEKSLDFYKKALGLKEVKRKEAEDGSFILV
                     YLGDGITSHTLELTWLRDWDRPYNLGDNEFHLALEVEEFDEAKKLHKDLDCICFENES
                     MGIYFIADPDNYWIEILPKNH"
     gene            complement(41852..42451)
                     /locus_tag="PC512_000441"
     CDS             complement(41852..42451)
                     /locus_tag="PC512_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440220.1"
                     /translation="MESRGYKEDLKKMILDMAHKELESYVSQKGAKKYFEGNLDKIIN
                     NNIKKFNQSIGLNRVYLKMLKKCAYQESVTSISRTIKKEALFKSKKELFAFSEYLKLD
                     INKRLSYNQILRKISRYIYYNRSSYAQKYVVFKRGDEEYLLEPEKIKDELISSYRSKT
                     REDMRSIAKLLDIEVEDDYNAEDIRKKVINYIIKEKLKS"
     gene            complement(42652..42864)
                     /locus_tag="PC512_000442"
     CDS             complement(42652..42864)
                     /locus_tag="PC512_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HDF2440221.1"
                     /translation="MKKKLLVEGMSCGHCVNHLKTALTEDIDGIEVLDVDLENKCASV
                     DMKDDVSIEKLKEVIAELGFELKGIE"
     gene            complement(42937..44652)
                     /locus_tag="PC512_000443"
     CDS             complement(42937..44652)
                     /locus_tag="PC512_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2440222.1"
                     /translation="MKRIKVLTVVLAITLMVAGCSNTKTKQSSSDSSLQSQSSIDAKY
                     INLTMVTPKTINPITNTDKSVGYIMNLVYDSLFTIDENYNVIPQLVKEYNIAQDGMSI
                     DIKLKDAKWHDGKNITSNDVNYTIGLIQKSADSPYNEFTKNIASVNIKSDKDFTIKFK
                     ARYAFSIDSLIFPIVSQNHLDSKDVNDKNNNMIGNGKYKIESYTEREGMVLSVNKDYY
                     EEVPKTMKNIKVGMVPNEDARTSMVMALDSDITNVTLNDLSKFQEKEFNITKYQGRDY
                     ECVLFNYNNPFFKDVNFRKAIAHSIDKDRIISEGYMDDATPVNFPLNSKSKYYNSEMK
                     DLEFNKDKAIECLAKVEYANVNSVNQNDNKVKNQKKSAKKNSKKLTPEEEAKAKKAEE
                     DRIKKEAEEKKNREKEEVKKSLSEMNLKIIVNRDNSERIKTANIINENLKAIGINSTV
                     NQLSDKDMENALNSKNYDLALVGWKLSIIPDASSIIASSGYTDDKLNGYMSALTSSTS
                     EIETKKAYKDVQTYIKDNATFISLAVRNNYIVSNSRLKGKITPNDFDVYEGISNLDIK
                     SNESN"
     gene            complement(44652..45206)
                     /locus_tag="PC512_000444"
     CDS             complement(44652..45206)
                     /locus_tag="PC512_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HDF2440223.1"
                     /translation="MNSKKVLILSIFIILFGALLMESKVIHKFLYPKKYSEYVEKYSK
                     EFNLDENIVYSVIKAESKFNSSAVSKKEAKGLMQILDITRDWGAEELNLKNVDIFDPE
                     TNIRLGCWYLSKLYKEFGKLDLVIAAYNGGSGNVKKWLENNEYSKDGENLHDIPFKQT
                     SKYVEKVKNNYEHYNKIYGKKGKN"
     gene            complement(45199..45801)
                     /locus_tag="PC512_000445"
     CDS             complement(45199..45801)
                     /locus_tag="PC512_000445"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HDF2440224.1"
                     /translation="MLILGLTGGIGCGKSSLSNIFRNLNIPIVDADIISRKIFEDKLL
                     LEKVFVHFGQSIKNDDGTLNRKALGKIVFSDEEKLKELNNLTHPRIREKIISEIEKLR
                     KKGENIVVLDAAILVESGFLDMVDKLLVVTCKQEVQISRIQKRDNCSEQEALSRINSQ
                     MSQEEKSKYGDYIIDNSGTITELESKAHKFIEYMKENWRE"
     gene            complement(45810..48458)
                     /gene="polA"
                     /locus_tag="PC512_000446"
     CDS             complement(45810..48458)
                     /gene="polA"
                     /locus_tag="PC512_000446"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HDF2440225.1"
                     /translation="MEKKLIIIDGNSIINRAFYALPEMNNKEGLKTNAIYGFTTMLFK
                     MIDIYKPTHISVAFDRKAPTFRHLEYKDYKAGRKGMPDELAEQLQPLKDLLDKFRINR
                     LEIDGYEADDIIGTVSKKAEENGYKVYIVTGDKDAIQLASDNTTTLITKKGVGEVEEY
                     NFNSVIEKYEMTPTQFIDLKGLMGDKSDNIPGVPGIGEKTGIKLIKEFSSIENLIENT
                     DKLKGSVKKKIEENKEIAIQSKRLATIIRDVPIEVDLDSMIFGDYDKDELLDKFRYFG
                     FTSLLSRLVDLVDSDDTEHVEEKIEILKLKDIEKFIDEVNKKGQVILKTVRGQGNILE
                     KNIIYIFISVDGEKIYYVDSNEVSKLDSIFSNNEIKKYGYNLKDDYISLKPYNINLEN
                     MYFDITIAEYLIDSTSSTSYDCSAIAMKYLSKKVKSKEELLGKGVKSKNYEDLEFEDL
                     AEYMGQIICTVKETVPMMERSLMDMSMDGLFYHVEMPLVEVLGHMEYEGIKVDKSILD
                     ELSVEFKEIIATLEKEIYELSGEPFNINSPKQLGVILFEKLELPIIKKTKTGYSTNAD
                     VLEKLRDKHPIIDKITEYRQIVKLNSTYVEGLLNIINPESNRIHSSFNQTITTTGRIS
                     STEPNLQNIPIKMEMGRKIRKVFIADDNCKLVDADYSQVELRVLAHMSQDENMIEAFK
                     HHEDIHTKTASQVFNVPMEDVTSELRGAAKAVNFGIIYGKSDFGLADDLNIPVPKAKE
                     YIESYFAKYHKIKEFMDTTVEKASEDGYAVTILNRRRYIPEIKSSNFMERNRGKRFAM
                     NAPIQGSAADIIKIAMINVHKKLEENNLKSKLILQVHDELIVEAIDDEIDIVKKIVKE
                     EMENAVNMDVHLDVDLNVGSSWYETK"
     gene            48610..48697
                     /locus_tag="PC512_000447"
     tRNA            48610..48697
                     /locus_tag="PC512_000447"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:48644..48646,aa:Leu,seq:caa)
     gene            complement(48884..49327)
                     /locus_tag="PC512_000448"
     CDS             complement(48884..49327)
                     /locus_tag="PC512_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440226.1"
                     /translation="MKKNMLYVGIIYFICGILLVLLATFTEFSFEAFIWGLSGAALGP
                     GVCMILQYMYWSKPERAVDYEEKIKNQRIEMNDERRIMLRDKAGRITNQIMCYVLVIL
                     IFIVSILSVFSVMVISKWVLVVLGLLILFQFICSVVVYNKLDKRL"
     gene            complement(49330..49527)
                     /locus_tag="PC512_000449"
     CDS             complement(49330..49527)
                     /locus_tag="PC512_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004631111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2440227.1"
                     /translation="MKNRLEEIRKERGIKQEELASILQVSRQTIGSLENGRYNPSIIL
                     AFKIARYFDMSIEEIFIYEEE"
     gene            complement(49719..50585)
                     /locus_tag="PC512_000450"
     CDS             complement(49719..50585)
                     /locus_tag="PC512_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF2440228.1"
                     /translation="MEWINKLNQAITYIEENLESGVDYAEAAKIACCSTFHFQRMFSY
                     IAEVPLSEYIRRRRMTKAAFELQNSNIKILELSEKYGYDSPTSFNRAFQNIHNISPSA
                     ARAKGVVLKAYPKMTLSIYVKGNIEMQYRIVEKKGFRIVGIKESMNMIVEECFEKVPK
                     LWAKCIKNGTIDKLSELINNEPCGLLGVSVCTNSKGLDYYIAAPTDKPVLEDTHEYLI
                     PSGTWAVFECVSPMPNALAIQELQKRIITEWLPSSGYVYANLPDIELYPNGDINAPDY
                     TTEVWIPIQKPS"
     gene            complement(50811..51680)
                     /locus_tag="PC512_000451"
     CDS             complement(50811..51680)
                     /locus_tag="PC512_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF2440229.1"
                     /translation="MDYKTIILNRKSVREYKNTDIKEEYLSEIKKYSESCKKLVPEID
                     VDVRIMNRSEVFNNLDKVAGYKGNMIDSPSYIIILSDIKDNYIENSGYIGESIIFKVT
                     ELGIGSCWVTFEDGKKVKEKLGINSDKEVTGIIAIGYGENVSNAKVLNATKTGQNYSK
                     SDMQVVTDKGSTRLGVEDVVYMNEWGNVASIEILEERALLDAFHYARLAPSTLNRQPW
                     RFIVDGGTVVLAVRKDGHTNLYEEKIDIGIVMLYFATIISATMFDLKWNLGTPDKDYK
                     VPEDYKIVGYCNI"
     gene            complement(52186..52407)
                     /locus_tag="PC512_000452"
     CDS             complement(52186..52407)
                     /locus_tag="PC512_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440230.1"
                     /translation="MNVNNHKCPECGEHSKKFEIVEENEDCVIFECYTCGTISILKYC
                     ENCKEFVFVNIPNNVETYEYCCGKCNNKI"
     gene            complement(52909..53889)
                     /locus_tag="PC512_000453"
     CDS             complement(52909..53889)
                     /locus_tag="PC512_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440231.1"
                     /translation="MGDTSRFYESVKNKYPKLKDGTRVHLWPKENIIIGPIYDEEDGY
                     KKSIGNVDSLSWKQIVILAECDGKNTTDDIINILSNRYRNIHNMKEKVMEFFMFYENV
                     YLTFEDDIQTLSSVFEITGNKSYITPLYFTIEIDGDNNTNDYFSEITSLLNCMYEKGC
                     RFIEVIGEDILKNKSMREIFQYMLDHFDLIVVTKDSFTIDRSLIKELDNYRHKVIWKV
                     YSKNDDTRIKLKEDIKITSLIKRGHTVVRGDREKAIKIEDMRFKDTKERFSKYGAEWS
                     HLYISSDGSVKSYSFQKDKRIYLGNIFNNSVEEIFLEMQNKIDKLEIVYQ"
     gene            complement(54053..54925)
                     /locus_tag="PC512_000454"
     CDS             complement(54053..54925)
                     /locus_tag="PC512_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDF2440232.1"
                     /translation="MIIKVSMTVLVLILLYILYKYETQHIETTEYTIFNKKIPKEFDN
                     FKIVQVSDLHNKVFDKNNKVLIDKIESLNPDVIFITGDLVDGENKNFQVALDLIDNLV
                     EKYEVYHIIGNHEQKSLIKKYKHLYKDYFKELYSKKIINMENESVRIYRGNSHLNLYG
                     LIIPLECYPYLFANNKKLELSDNFVEDNLGKVNENEYNILLAHTPFFFEKYAKWGADL
                     VLAGHVHGGIIRIPFVGGVLSPNREFFPKYDWGKYEKDNSTMILNKGLGGSKVLIRLN
                     CKPEIVKITFKYEK"
     gene            complement(55089..55640)
                     /locus_tag="PC512_000455"
     CDS             complement(55089..55640)
                     /locus_tag="PC512_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2440233.1"
                     /translation="MDNKFPNVGENLRLLRQEMGISLDKASKMTGVSKAMLGQIERGE
                     SSPTVSTLWKISSGFKINFTTLLNENTNTYEVIKKEEVEPIVEQKGNMKLYPIYPFSP
                     QRRFELFIIELEENCTHVSSTHSHVLEEYVLVIEGKLDLNVDGKTYILESGHSIRFDG
                     TLEHIYKNLNKGKTIFHNIEVYR"
     gene            complement(55660..56562)
                     /locus_tag="PC512_000456"
     CDS             complement(55660..56562)
                     /locus_tag="PC512_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HDF2440234.1"
                     /translation="MSKKGRVVKVQHFSVNDGDGIRTTIFLEGCKLKCKWCSNPDSWS
                     NIVKLGVMKDKCVSCNRCIDVCPQNISSLFDRAQINNKCDLCGECIKVCLKDAICIMT
                     EEMSVEEIVEEVEKDFIFFFESNGGITFSGGEPTLQIDFLRELVDIFYDKGINIAIET
                     CGYFDWNKVNDVFEKIDHIFVDIKSMDDNIHKEYTGVSNKIILDNICRLSKLNKSMVI
                     RVPIIYGVNDSEENIRNTALFVKQNVPGGKMELLPYHKFGIDKYKALGLEDYIYEFDD
                     ICNNHMLKLKEIVELTGVKIIEYK"
     gene            complement(56577..58949)
                     /locus_tag="PC512_000457"
     CDS             complement(56577..58949)
                     /locus_tag="PC512_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase/glycerol dehydratase
                     family glycyl radical enzyme"
                     /protein_id="HDF2440235.1"
                     /translation="MSQTNRIEAFRQEYINSKPMICCERARIFTESHKKTEGEAICIR
                     RAKAFLETCKELPIKIFENELIVGTAGKFRRTGILTPEFSWQWVDKEMDTFDKRTQDP
                     YVISKEQIEFIRKEIFPYWKGKSLEEVFLARIPEDTAKILVDTGIIDNDSKWRQAVGE
                     VTPDYQDILFVKGYKGIKEDADKKIKELDISVSENIEKIDFYKSVSIVAQGIMTLAQR
                     YSNLAKEMSKQETDEKRKLELIKISEICMNVPANPPTNFYEAIQFVWFVQLGGILSEN
                     PLALNLGRFDQYMYPYYENDAREGKITESEAQELIEALWIKLSEWVWTISANTANYFA
                     GYNQFQNLTVGGKKRNGTDGTNDISYMCLKATESVKTHQPGLSVRVSQGAPDNFVMAV
                     AKLVKQGTGFPAIHSDSAGAQMLLQDGYDAEDARDWSNCGCVVPHFRKTGQWTSAVNI
                     NFAAALEYAMNEGKSRLTGEKMGLDTKNITEFTSFEELKDEFLKQLAYLVKSSVIGTT
                     VAQQIHKEMVPRPFLSTCVDGCLDKGVDLSKGGAKYNIGPVLTGIGLGVVSNSLAAIK
                     KLVFEDKVTTLEELTKALNNDWEGYEELRKLALDVPKYGNDNDYVDSLAIEVSDFYYT
                     ETRKYKDIFGSKFNSAFMGISNYVPTGKIVGATPCGRKATKPLTEGVSPFVGTDTTSP
                     LAAMKSASKINHDVHTGGTLLNLRLNQDLVETERGLRNLTSMIKSYFALGGFHVQFNT
                     ISNDTLLKAQENPEEYKDLLVRVAGYSTQFVNLSREMQDAIIARNSHSNF"
     gene            complement(59170..59859)
                     /locus_tag="PC512_000458"
     CDS             complement(59170..59859)
                     /locus_tag="PC512_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440236.1"
                     /translation="MKVKRNINRVAIIVALNLSLALMVGCMSPVYDKNLSSSEQISKD
                     SLKEQVEDKKDESIELFNNYSQKINDAKGREEVKKDLSQRFSKAIIDSGYSITDSKSD
                     GSFVVSINGAEKPPEKNIRSLFYSMSEDDKEGKVTIDILCAKEYPEDDKLSESDKYIK
                     FIYNLFKSLTNTNLTEKEIFSMVEEDFNKGVGVVELPYMKDIHVEVNKVKQSTKVLKL
                     SLVYKFDISNH"
     gene            complement(60100..61479)
                     /locus_tag="PC512_000459"
     CDS             complement(60100..61479)
                     /locus_tag="PC512_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF2440237.1"
                     /translation="MLNFMTELLVVLSIFIQFSIMNGILIYKKDSKKNEKIVFYIVLF
                     LIYIIIQISRLFNGGNYFSNINYLFYILAFIAWGGYYNYFYKMGYIKYSIFFYLFSVY
                     YKCLDAVIYRILFFAITGNVISSKESLLVPHLESIKIQIYSNLIIILIYLIFSFFRKS
                     IKLISQDKRNYVYLLFALLVNTMNMLVNYVLKKLERFGSLHSEGYYFDNFVNPKLVGA
                     SSIFLILLFKEIIKENRLKSQAELIKNKLDMQYAHYLSIQESHMRVKKLYHDINNHIY
                     CIDNLRNNSKEINEYVNNLKDEIKTFKYIYNTGNMILDIIINEKSEICLKKGIKFTCS
                     INFSKVNFVKPIDVSSIFSNILDNAIEACDKIVDENVNKYIRIKGTMTRSFFVLKCEN
                     SKLNQLTFNKNILLTNKMDKFVHGIGIQSIKSSLQKYNGELLFENSIDKFILNIYIPL
                     DQDTDSWGD"
     gene            complement(61473..62186)
                     /gene="rgbR"
                     /locus_tag="PC512_000460"
     CDS             complement(61473..62186)
                     /gene="rgbR"
                     /locus_tag="PC512_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RgbR"
                     /protein_id="HDF2440238.1"
                     /translation="MIKIAVCEDEKETQLLIEDYLENILKDISIEYEIQKYISGEELL
                     ESNLKDIDILLLDIKMEKLNGMDTARKIREVDNEMEIIFVTSLIDYVQEGYEVRAYRY
                     LLKPIELEELKKHVLTCIKDIEINKESHITIKNKSNTYKIYLNEIKYIEVQKKDMLIH
                     TINKNFDIKYSLGKIEKELNPYKFIRCHKSFIVNLRYVENIKPNTAILESGEEVPISR
                     YRYKEVKEKFLKFLGDTIC"
     gene            complement(62436..62996)
                     /locus_tag="PC512_000461"
     CDS             complement(62436..62996)
                     /locus_tag="PC512_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HDF2440239.1"
                     /translation="MSAMEKKIKFKFDWYSSPDKIEKWLEDIEAKGYNLYKINKFGGI
                     FYFHKGSPRKIKYTVDYYYDVENNYFDEHKSNGWNLVFRSIGSFMGTSAWYIWSKEYK
                     DIPPKLYSDSDKKNKVKSILFMNMFIFFMLVVIFIYLLNIEIRNLYSGYGASVTAIVL
                     QIILLILYAVQLYRRLMYYLRLKKFK"
     gene            complement(63092..63895)
                     /gene="zupT"
                     /locus_tag="PC512_000462"
     CDS             complement(63092..63895)
                     /gene="zupT"
                     /locus_tag="PC512_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter ZupT"
                     /protein_id="HDF2440240.1"
                     /translation="MNNVIFAFLITLLAGLSTGIGSCIAFFAKKTNTKFLSISLGFSA
                     GVMIYVSMIEIFPKAQDALTKSMGEKLGSWSTVIAFFIGMAIIAVIDKLIPQEENPHE
                     IKKMENIEEKNIKKNKSLLRTGIFTAMAIAIHNFPEGLATFISALDDVTIAIPIAIAI
                     AIHNIPEGISVSVPVYYATGDKKKAFYYSFLSGMSEPLGAIIGYVLLRNFLNDITLGI
                     VFAIVGGIMVFISLDELLPSAREYGEHHLSIYGLIAGMGVMAISLLLFK"
     gene            complement(64046..65209)
                     /locus_tag="PC512_000463"
     CDS             complement(64046..65209)
                     /locus_tag="PC512_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2440241.1"
                     /translation="MDIKEITKSYKDYVIKLRREFHENPEKSMEEVRTSKRVKEELDK
                     IGIPYVSAGGTGVIATIKGANPGKTVALRGDMDALQVVECTDVEYKSKNEGLMHACGH
                     DGHTSMLLGAAKVLNDIKDSINGTVKLFFQPGEEVGKGARAMIQDGAMEGVDSVFGIH
                     LWTDVESGTISVEEGPRMASADFFKITVKGRGGHGSLPHQGVDAVLASSAIVMNLQSM
                     VSREVSPLEPLVVSVGVLNSGTRFNVIASEAVLEGTIRLFNPELRKQIPGILERIAKS
                     TAEAYRADAELEYGYLTPAVINDKECSKIATDAAIKLFGEDCITLFEKVTGAEDLAEF
                     MNIAPGALAFVGARNESKGACYPHHHGCFNIDEDALEIGTALYVQYAVDFLNK"
     gene            complement(65269..66456)
                     /locus_tag="PC512_000464"
     CDS             complement(65269..66456)
                     /locus_tag="PC512_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440242.1"
                     /translation="MEAITAFCLVLVSLTIGDIVSAKTKAFVPSVFVSAIIFIVGFWT
                     FFPENIVDLAALGTPLAQLGMLLLITHMGTMMSIKELAGQWKTIVIALAGIVGICVGA
                     LALGTVVFGWDTAVIATPPLTGGLVASIMMADAATAKGLASLSVLAILMYVAQGFAGY
                     PITALMLKKEGKRLLSDFRSGKVTVNTDEEKVKDLPEQKSRFKIIPDLPEKYDTTYMI
                     ILRLGFVAWLAVQFTNLTNEVVSRYVICLIFGVIASELGIVDRKPLNKSGSFGWLMTS
                     LMAFIFAGLAKATPAMLVEMAVPLVGIIIFGVIGMGIFSIIVGKLLGESKEMAFSVSL
                     TSLYGFPPNYILTEEAVKALAETPEEKEFLMDKMLPKMLVGGFTTVTIASVVIAGIFV
                     NLI"
     gene            complement(66819..68519)
                     /locus_tag="PC512_000465"
     CDS             complement(66819..68519)
                     /locus_tag="PC512_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2440243.1"
                     /translation="MIKQFVKYYKPYKKIFTLDLIAAFLFSLCDLVYPMITRNIMDDV
                     VPNKNLRMLVVFAVALILIFIAKAGLNYFMQYWGHVIGVDMQADMRNEVFTHLQRLPN
                     TYFDNNKSGVTMSRIVNDLMDITELAHHGPEDLFISIVMLVGSFFILIDINIPLTLII
                     FAILPFIIWFAIAKKDKMNIAFMKSRVTIGDVNATLENSIAGMKVTKSFCTEKEELNK
                     FVRSNKLFRRARQDSYKVMAEYYSGMNLYMDILEWVVVIAGGYFTYIGKITLGDFAAY
                     ILYVKMFIQPMKKLINFTEQYQNGMTGFKRFIEIMEQDHQKEAKNPIELENVKGDIEI
                     ENISFTYEDKTQVLDNLSLSIKAGKTIALVGPSGGGKTTLCNLLPRFYEFDKGDIKID
                     GKSIKDVSLKSLRKNIGIVQQDVFLFTGTIRDNILCGNPNATDEEMIAAAKKARIHDF
                     VETLPDGYDTYIGERGVKLSGGQKQRISISRIFLKNPPIIILDEATSALDNVTEREIQ
                     ESLEELSKDRTNLVVAHRLTTIKNADEIIVLTDKGIEERGTHEELVNKNGVYSRLHNN
                     "
     gene            complement(68774..69049)
                     /locus_tag="PC512_000466"
     CDS             complement(68774..69049)
                     /locus_tag="PC512_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2440244.1"
                     /translation="MKKILVACGAGIATSTIVCDRVERLVKENNIQAEVEQCKIAECS
                     TKQEGADLIVSTTILPTTYDIPTIKATGYITGINTTALDKKILNALK"
     gene            complement(69168..69740)
                     /gene="mobB"
                     /locus_tag="PC512_000467"
     CDS             complement(69168..69740)
                     /gene="mobB"
                     /locus_tag="PC512_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-guanine dinucleotide biosynthesis
                     protein B"
                     /protein_id="HDF2440245.1"
                     /translation="MLLLDSFMKGHNFMYNILSVVSYSGVGKTTLIEGIIKELNKKGY
                     RVGVIKHTCHDFDMDEEGKDTYKHRKSGARKVCIISDKRVAYIEELKEKNPLYKMIQL
                     YEDMDLIIIEGYKNYRFKRLEVTRKGKYEDILSNKSDLIGIVSDIEYKLNIEQFNLND
                     YKNISKYIESCIKNEILSISNVEIKNILKE"
     gene            complement(69724..70905)
                     /locus_tag="PC512_000468"
     CDS             complement(69724..70905)
                     /locus_tag="PC512_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin molybdotransferase MoeA"
                     /protein_id="HDF2440246.1"
                     /translation="MIELEDAIKIIEKNVLPINRVKIVNLIDAVNKVVAEDIYSTIDS
                     PPFDRSPYDGYAYNANSENRNLKVIGTLYAGDVFNRVLNKNEAVKIMTGGKIPQGANC
                     VIKKEDVTVIGDMITLNIKLKEYDNYIFKGEDIKKGQLIINKNQNIGYDGIGVLASLG
                     ISKVTVYDDLKVGILNTGTELQDINETLENGKIYDSNRYTLYSRLLKLGIQADTICNC
                     SDDILELEKKVKNMLQSVDFLITTGGVSVGDKDLIPDVFKKIGATELFWKINIKPGGA
                     CYVGTLGEKLLFGLSGNPHAAIVVFDNVIVPVIEYLTYKKGTHHIKAIFKGEFNKFSN
                     KDRFVSGKLYTSEGKLYVELNDKKDAKARLSATLRSNCMIKIKKNETIKENQLVDVVI
                     R"
     gene            complement(71116..71850)
                     /locus_tag="PC512_000469"
     CDS             complement(71116..71850)
                     /locus_tag="PC512_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440247.1"
                     /translation="MKLKRSLVCVTILGIILVGCHKENTKEKNQVASKATQQKTMTKV
                     QNDVNEIMNKDYKYIIKNMGIPYNTFYYIKPKVLKESNTMQDINTSSYMTLVYPKYTG
                     NDELDGSALYVDINENKVVNVETNSFSSQGISVIDAESSIVIEKSDHEKSAVSLENFR
                     HIDLGEYVGVEDSRINEIVGDANYDLTAYNHEGSKVVKSYRLKEDNKILKKEVLTISI
                     VDNKIKSIKTIESDKIVKIIKGTLLE"
     gene            72212..73117
                     /locus_tag="PC512_000470"
     CDS             72212..73117
                     /locus_tag="PC512_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF2440248.1"
                     /translation="MDFKQLEVFVAVAKHQSFSKAARELFLTQPTVSAHIQNLERELE
                     TVLINRSNKVITLTKSGEILYEHAIYILNNCKRAIYDIKEYSGKIEGIIDIACSSIPE
                     TYILPDFMKSFSMSYPDVKFSISHYDSQYAISEILNERISFGLVGSKINNPQIEYLDL
                     LDDELVLITPSDFKIDNKNNCIDIGELAYLNFIMRKEGSGTRNLILNTLSKNNFPVSK
                     LNVIAHVESNEAIKEMVRLGLGVSFISYISAIDYLNAGKIKCYKIKDVDFTRKFFFIY
                     SKKKTFSPLEDKFLNRLCEYFEIII"
     gene            complement(73277..74119)
                     /locus_tag="PC512_000471"
     CDS             complement(73277..74119)
                     /locus_tag="PC512_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDF2440249.1"
                     /translation="MTTSSKKLETISPDSKITRKDFWKCFRRSLTLDSSWNYERMQNI
                     AYAYMMAPIIRRLYKDDKEKKSKALKRHLEFMSVTPHISTLLVGISGAMEEENAKNKE
                     FDANSINAVKSSLMGPVSGIGDSFFWGTLKLIAAGVGIALASQGNIMGPILFLLIINV
                     PHFIIRYICLDKGFKYGTQFFKDVSGSSIVSKVMEAASMLGLMVIGGMTASNVMLKLS
                     VNVGSGEWAEPIQTYLDQIMPCMLPAMIFGIMYWLLGKKVKTTTILISVMIICIVLAA
                     IGVV"
     gene            complement(74103..74861)
                     /locus_tag="PC512_000472"
     CDS             complement(74103..74861)
                     /locus_tag="PC512_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2440250.1"
                     /translation="MEFTQVILITLIAFFAYMHSFVGSTMHNRPIVVAPLVGLALGNL
                     HTGIVIGSTLELVFMGAFPVGASNPPDFVSGSIIATAFVILTGQDVSAAVVLAVPIAT
                     LVLLIDNFLMTVVLTWGAHIADRYAEEGNIEGVERVQLLFGIGNKLILAIIVGIGFSL
                     GVPVIEKILSFIPSYVTHGMDVAAGVIPAIGFAMLARMMLNKKTVAFLLLGFILVAYL
                     NITVTGVALFGLAIALIYVNFVGEKEVIVDDNEF"
     gene            complement(74878..75348)
                     /locus_tag="PC512_000473"
     CDS             complement(74878..75348)
                     /locus_tag="PC512_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2440251.1"
                     /translation="MIKLVRVDHRLIHGQVAFTWTKFLSTDCILIASDDLLKDELRMA
                     GLKMAKPSNVKLVMKSIADSIKALNSGVTDKYNLLILCESVEDVYRLAKEVKAIKSIN
                     LGGTKSDDNRENISKAVHVSKDDIKMIKELDSEGVNVFVQLVPDDDATNVMKLI"
     gene            complement(75348..76091)
                     /locus_tag="PC512_000474"
     CDS             complement(75348..76091)
                     /locus_tag="PC512_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane biogenesis protein"
                     /protein_id="HDF2440252.1"
                     /translation="MKKKGILSVFKSKKPIIAMIHLKGDTPEDIFERAKKEITIFEEN
                     GVDGIMLENYYGNYYDLERILEYVSKANLSIPYGVNCLNVDTMGFELATKYNASYIQV
                     DSVVGHVKPRDEATLEEFFKLQRSKCPAYLIGGVRFKYQPVLSENDVEEDLKIGMTRC
                     DAIAVTENATGQETSMEKIELFRKNLGDFPLVIAAGVTLENAKKQLKLGDMAIIGSYF
                     KDNYKDFGDVSVEHVKTFMDEIKKIREEL"
     gene            complement(76095..76508)
                     /locus_tag="PC512_000475"
     CDS             complement(76095..76508)
                     /locus_tag="PC512_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2440253.1"
                     /translation="MKKIILASHGDFSKGLLNAVKMIVGDLADCVSSYGLYPGQSASD
                     FALELEKTISEDKECEYIILSDLYGASVCTAMLRLTNLHNVRLFSGMNLNMVLELLTR
                     FSDELTVEDIDQLVEESRRGIQSVTLQIKEEEEVF"
     gene            complement(76534..77118)
                     /locus_tag="PC512_000476"
                     /pseudo
     CDS             complement(76534..77118)
                     /locus_tag="PC512_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896033.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
     gene            complement(77303..77686)
                     /locus_tag="PC512_000477"
     CDS             complement(77303..77686)
                     /locus_tag="PC512_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2440254.1"
                     /translation="MKISKLPEAELKVMRYIWEANDVLTSKELVAAMEEKYEWNESTT
                     FTVLKRLERREFLSTEKIGKLTHYNAMVKEKKYLRFETKEFLKNIHKNSISSLISALH
                     SKDDEVDEDKLIELEEHFKNLKEKE"
     gene            complement(77796..78173)
                     /locus_tag="PC512_000478"
     CDS             complement(77796..78173)
                     /locus_tag="PC512_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2440255.1"
                     /translation="MKEEILVEKLLRAELIVMEYLWKKDSLVTKKEIVKEMRQVYGWH
                     KSTIKILLKRLVDKGYLARDIIKFQSHYKIIIDNKEYYAFKKKVLKSSKSRKIMRSLT
                     TTHKSISKEKLDALEEYYRNLEE"
BASE COUNT        24844 a        14318 c         8295 g        30846 t
ORIGIN      
        1 ataaaataat taaagataaa aggagtattt tatgaacata cttggattaa tagttgaata
       61 taacccattt cataatggac acatatatca tttatctaaa tctatagaaa aaacaaatgc
      121 aacacatact gtagcaataa tgagtggaaa ttttctacaa agaggcgaac cagctttatt
      181 tgataaatac actagagcaa aaattgctgt cgaaaatggt gtagacttag ttatagaatt
      241 accaacttta tttgcttgtc aaagtgctga aattttttct catggtgcta taacaatttt
      301 aaattcacta aactgcataa attctatatg ttttggtagt gaagaaggaa atacagaaat
      361 tctttataat atagctgaaa ttttagcaaa tgaaccaaat gaatttaagt tacttttaaa
      421 aaaatattta gatgatggtc tgttatttcc aacagctaga gctaatgcac tttttgatta
      481 tatacatcaa gacaaaaaaa ataattttat acaaaattat tcaaaggaac aattatcaaa
      541 aacattaaat tcatcaaaca acatactggg tatagaatac ataaaaaacc tcatccattt
      601 aaacagtagt ataaaaccat ttactatctc cagggtccaa tcagagtata attccgaaga
      661 aattgagagt gatatttgtt ctgctactgc tataagaact tcacttaaag aaaatacaga
      721 cctttttcat ttaaaaaatg ttattccaga aaaaacttat aacatcctaa atgaaaaaat
      781 agataatggt tttttaccta tgtttgatga cttcttcttt gatattttaa aaacaattat
      841 acttagagat atggacactt taaaagagta ttttgaagta aatgaaggca tagaaaacag
      901 aatctataaa gatatcttta catctgaatt tctacatgaa ctacaattag caattaaatc
      961 caagcgatac actttaacca aaatcaaacg aactctaaac aatatattgt taggtattaa
     1021 aaaaagcgac atgcaactta taaaaaacat agatactata ccttatataa gaatacttgc
     1081 ttttaatgat aaaggtagag aaattctaaa agagataaaa aataaatctg aaataaaaat
     1141 aataaacaag ttttcaaata tatcattttc attagatgat acgattttta aaacactcat
     1201 aagttatgat ataaaagcta caaatatata taattcaata tattataaaa acaataaaga
     1261 tttagtaaaa ggccctatgg atttttatac tcatccaata tatgtaaagt agttttttaa
     1321 aataactata tttataaaaa tcattttatt aactctttat tatataagat acaatagtct
     1381 tactttattt atgtacacat gcttttagga tgacaacatc aacttaaata ttatgttact
     1441 ttctaaattt aagtaaatat tgccatccta aaaattttac aatttagctt cagatttaaa
     1501 agtaaagttt aaaatattat atttaaatct aatttaatat tttttgtttt gtaaatatta
     1561 ttaaattaat atttctaata tattttccct ggatttaaaa tatttttagg gtcaaaagct
     1621 aactttatat ttttaattaa catcatataa gcatctgaat ttgattcatg taagtactct
     1681 tttttagcat atcctatgcc atgttcacca gaaacttgac cactaagttc tctagatttt
     1741 ttatacatat agtcaaaagt ttcttttaat cttattttcc atgtattatc atccatacca
     1801 tcttttaaaa tatatatgtg tagatttcca tctcctgcat gaccaaaact ttttattctt
     1861 atttttaatt tgtcttgaag ctcgtgagtg tatcttataa actctgctat cttatctctt
     1921 ggaacaacga catcacattc atccatttgt gtcgtagatg cctttatagc ttctaaaaat
     1981 gcacctctgg ctgaccatat agaatcgttt ctttcttgtg tatctgatat aaatacatct
     2041 aatgcaccat tttctaaaca taaattagct actttttcat attctttttc tatatcttca
     2101 gtgctatttc catcaaatgt aagcaaaaga taagcatctg atgtattatc tggaaacttt
     2161 ttacctaaaa attcttctgc tgccaatatc acatctcttt ccataaattc tatagccgtt
     2221 ggtattgatt ttgattttat tattttagga acagtttcta ttgccattga taaatctgga
     2281 aatggtataa gcaaacttat acttttcttt ggtaaaggaa gcaattttaa tatagcttta
     2341 gtaactattc ctaaagtacc ttctgagccc actaataaat cctttatact atatccagaa
     2401 ctatttttaa ccacctttcc acctacattt ataatttctc catttggtag tacaacttca
     2461 agacctctta cataatccct tgtaacgcca tattttactg ctctcatacc acctgcatta
     2521 gtgtttatat tacctgcaat tgtagcactt ttttcacctg ggtcaggtgg gtaaaataaa
     2581 tctctatctt gaacatattg acctattgtc atcaataaaa cacctggttc tactgtcaat
     2641 gttaaatttt cataatcaac ttcaagtatt ttattcattt tacatagatt aatcattatt
     2701 ccaccattta tggcaacagc agcacctaca agaccagtac cttgacctct tggtgtgact
     2761 ggtatattat ttttatatgc gtatttcatt attttagata cttgttcagt ttcaagtaca
     2821 tttactaaaa cttcagggta cttctcaatc cctccaagtt catcatgtga aaaatcttca
     2881 tttatatcac ttccaactaa tacattttct tctccacaag tatctattaa aaaatctata
     2941 tcttttttat cgattaattt atacatttct atccccctat ttagctgctg atgccatata
     3001 tttttgatta ttatctttgt tattttctat tttttcaatc aatttaggaa taatatcata
     3061 aatatcacct attaaagcta aatgtgctac atcaagtata ggcgctttat catctttatt
     3121 tattgctact atatagtcag caccctgcat ccctgcaaca aattgaacag ctccagatac
     3181 accacaagtt attatcaatt taggttttac agttctacca ctaagaccta tttgtttttt
     3241 agcatctatc caacctgctt ctattacagg tcttgttcct gccacttgag cgtttaactt
     3301 atcagctaat ttatatatca tctccatatc ttcttgtttt tttattgctc tacttgccac
     3361 aactatcact tcagcttctt ccagaccaac ttctttattt ttttctttta cactcagtac
     3421 cttaatttta gattttagtt cttttttttc tactttacat aaagttatct ttcctgtagt
     3481 attctctatt ttttctggtg ctgaaaatat tttatatctt acagtggcaa attgtggtct
     3541 attattaggt gtgtttatat gagccattat atttccacca aatgctggtc ttatttggtc
     3601 taaatcagta tttgattgaa tatcaagtat tgtacaatct gctgtaagac ctgttctaaa
     3661 tctagcggca agtcttggag ctaatgacct acctaatgta gttccaccaa ctaatactat
     3721 cgttggtttt attttatcta taaagttttc tattgctttt gaatatggtt ctatcctaaa
     3781 atctttaaat tcatcttcat catatacaaa tacttcatcc accccataag aaatcaaatt
     3841 actgcactta tcttttatgt cttttcctac aaatacacaa tacacaggtt gttttatttt
     3901 tgatgccatc tcacgagctt tacctataag ctcgtacgtt acaggatgta tatttccatt
     3961 atgatgttca acatatactg caattcccct ccattcatct ttattaattt gtactttact
     4021 actctctata aattcaaatg cgccttttgg tccacttttg acacacaact tgcacatctt
     4081 acagccagca cttatttcta ctatacctga cttttcttct atagccccaa aaggacatat
     4141 ttctaaaatt ctctttaagt cagttatttt atcttgattt acaactatct ttgacattta
     4201 ttactccccc ttacaccaac tttaattcct ctaatttatt tacaagtgca aaacttagtt
     4261 catctgcatt ttctcttaca atatttttat ctgtatttgg ctttggagga aatattctta
     4321 caacttgagt aggagaacca ttaagtccat agttattttc atttttatct tcaaagtcat
     4381 ctaagctata tacaggtatt tctctatctt tagtattaag ttttaattta aatgaaggta
     4441 gtcttggttg aaaaatgtct ttttctacag ttattaaaca tggatattca atctcacata
     4501 cttgtaaatc atttggcata tctatttcaa caactatact ttcatcttta acttcaatta
     4561 attttgtaac gttagtaaca tgaggtatat ctaaaaattc agctacttca ggtcccacct
     4621 gtgctgtatc accatcagta gtttgttttc cacaaattat taggtctacc tttcccatct
     4681 tcttaatacc ttgtgatatg gtataggaag tagccaatac atctgctcct ccaaatctcc
     4741 tatcacttat taatgctcct tcatcagctc ccatcataaa actttcttca attaccttct
     4801 ttgcctgagg aggacccatg ctaagtactt ttagattcgc tttcttatct tcctttattc
     4861 taagagctgt ttctaaagca tataggtcat agggattcat ttttgaatct actccatctc
     4921 tttttagtac tcctgtagtt tcatcaactt ctactgaagt cgttccagga acttgtttaa
     4981 tacatgtcaa aatttccata aagtacactc cttttttatt taactataac tgatactcca
     5041 tcaggtataa ctactacttt gctctcctta ccaactatac tattcgccat ttctaaagct
     5101 tctttaaagt taaatgcatg tttcatatgc atttttttta tcatttcagg attacactta
     5161 tctgttacca ttatcacagt atatttagat aatattctcg ctagtatctg aaattcccat
     5221 tggtctggaa tcgtatctac tctatcgaca cttctaattt tatctaaaag ttgttttgga
     5281 gaatctgcat ttgctacatt ttcataaaaa gattgacctc catgaccatc attacatgct
     5341 gaaatcatta ttattactcc accgtcttta caagtagctt cagctgctgt cattccttta
     5401 acagattgat aaatattttg gtctagtgga tatccaccat ttgtagttac aacaatatca
     5461 gattttatag aatttacttt tgataactct gttacaaatc tacatccttt agtatgtgct
     5521 ttttcgacat caccagcaaa ggaagcaatt atttttttat ctttatctat tacaacattc
     5581 aatatgaatg ctaattttgc aactttagct gcatatacca tatcctcatg aataggatta
     5641 ttattcaatt ttccagttct tgaattatca ctatctataa agtcactaca gtgattgtac
     5701 attatagtct ttgcagatgc gattcctgga agtacgcttt ttctgccacc tgaaaaacct
     5761 gcaaagaaat gaggttctat aaaaccttct gctatcaaaa gttctgcctc atatgctagt
     5821 ttgtttatat ataaatctcc acctgaaggc aatatcccta ctttacacat agatttatca
     5881 tcagtagata tatgcataac tatatcttca ttatctacta tttcttctcc cattttataa
     5941 attagctctt cccttgtact tggcctatga aatccagttg ccactataat cttcacatca
     6001 atttctggat taacattcct aatccttctt aatataattg gcatagttat tctacttggt
     6061 acaggtcttg tatggtcact tgtaattatg actacattct ttttcccctt aaccagttct
     6121 tccagagaat tagagcctat aggattattc atagattctt caactatctc ttcttgagtc
     6181 ttatgttcta tataattatc cgattttgac tccaaaacac cgagaaaacg ttcatcaggt
     6241 atttctaaaa tcattccttg ttttgaatac ggtactttta actttaccat ttttaatctc
     6301 ccattataat aaactataaa attggtatgt ggtcatacca gttttacatt tatataatag
     6361 taccattatc taccatttgc aagaataatt tattttataa caaactttta attttcattt
     6421 tttctataat ttttacttat aaaatccata tgttcctttg ctttctcaca tgcaagttct
     6481 acatcatttt ctacaactgc attgtatata gcttcatgct gtttaagcaa tatattttca
     6541 ttaaaaggtt ctgcgattat tttttctctt gcatcttcta taaatccatc aaataatttt
     6601 gatgctgtca taaaaagact ttgaattaaa taatttttac ttaatgttgc tagtttactg
     6661 tgaaattttt ggtctaataa taccagtact cgattattat cttttttatt agtttctacc
     6721 ctcatttcat ctattatatg tttcaattct ataacttcag aagaagttat tctctttgaa
     6781 gcaagttttg caatctcaat ttctaggatt attctaagct ctaatatatc ttcaagtgta
     6841 ccattattaa gtttaaaaat catagataaa ggttctatta aagttttttc tatatttgta
     6901 catataaaat ttccttcacc ctgtctgctt tctatcactc ccatagtctc taatacccta
     6961 atagcttccc ttatggaagt tctactcaca ttcatttgtt cagacagttc tctttctgat
     7021 agtaatttat cccccttttt taactctcca tttagtattt tatattgtat ttgctcaatt
     7081 acttgttcat aaactttttt actagctata ctattaaaca ttttttcctc caatatgata
     7141 atcgttgttg taatatatat ctattatata tcttaagcca ttacattcat atatttttat
     7201 tacttttaat ataatatctt ataactcaaa tttacaggtg atattatgaa aaaaaataaa
     7261 attattgctt tttttgctcc atctatcata gttggagttc tagttttagg gattatccta
     7321 tacccaaatg aagctataaa atctgcaaga gaaggctttt ctatatggtc taatgtttta
     7381 gttccatcac tactaccatt tataattgga gcaaacttaa ttgttgattt aaaaatagtg
     7441 gatattatag ggtttatcat caatcccata actagatttg tatttaatgt ttcaggaaag
     7501 agcgctttag cttttgctat atctacagta tctggttatc cagtaggagt aagtttagct
     7561 tctgaattta ggagtaatgg acaaatttct aagtatgaag cacaaagact tgtgtctttt
     7621 tgttctacat caggaccttt attcataata ggttcggttg gtacaggtat gttccaaaat
     7681 tcaaacttag gttatttaat gattctctgc cattatctag gaactatatt ggttggtctt
     7741 ttctttagaa attatggtaa tgaaaacctt ccaaagacaa aattggattt aaaaacaaat
     7801 ataaaaaatg taatcaacat tagaaattca agtgggaatg gtttttttgt tttatttgga
     7861 aatgctgtat ttaatggagt aaacacatta cttacagttg gtggatttgt aattgttttt
     7921 tcagtagtat ttaaaatact atctcttttt aatgtaatct cattaatagc atcagttata
     7981 tatttgcctc tttcattttt aggtgttagt aaagaactct gtcaagcatt tgtaagtggt
     8041 ctatttgaaa ttactatagg atgcaataaa gtatctagta taacaagttc tccagaaatt
     8101 ttaagagcat ctttagctag ttttttgata ggatttagtg gattatccat cctagctcaa
     8161 tgttgtacat ttctatcaaa aacggacata gatttaaaat tatacatact aagtaaattt
     8221 gcgcatggag ttttagctgc tatctttata tttatacttt atccaattgc aaactctgct
     8281 gtgttggttt ctagctttgc tgatacatac aacgttatat ataataattt aatctggttt
     8341 tattacctta gctattatga tacaattctt caaattgtag taataattta tctaatctca
     8401 gccgtattta ttgcaaaaaa acatatgaaa actttatcta caaatgggaa actaatgcga
     8461 tataaaaata cttttttcac taagaaattt tcacgaaaaa aataaaacta aaaataaaac
     8521 taataaaact taactaaata cttccatttt tttattatat ttgtcataat tttaataacc
     8581 tttttaatta gtttaacagc atagttattt catcacaatt taataatttt attagaaata
     8641 tttttcaaaa aattctcctt aatcacatat atcacacttg tataagttta ctgggaaatt
     8701 tttccattat ataatatttc atttatatta tataataaat accgacctaa acttaccaaa
     8761 tcaaactaag aggagtggtt gaaaatggca acaagaccta tagaaataga cgaatataaa
     8821 aagataatgg aactattaca tactggcttt acttatagtg aaaatggcgt tgaaaaaaga
     8881 tttagaaaaa atcctaaagt tgcattggca ctaatgttag aagctaattt aggtctaaga
     8941 atatcagata ttttaagatt aaagataggt aattttaaag gtaatatgtt ggaaataaat
     9001 gaaaaaaaga cgggcaaatt acagtataga ccagttaata aaaatataat tgagtccata
     9061 aatgaacatg caagaaagta taatcttaaa tcaaatgact acttagtaaa tataaagaca
     9121 aaggctattc aaaaacagtt gaggataatt tgtaaacact taaatctgta taatataagt
     9181 acacatagct ttagaaagct ctatgctact actcaatttg aaaagagtaa caataattta
     9241 gagttggtta aagaactttt aaatcacagc tctgtagcca ctacacagcg atatataagg
     9301 gtaactcagc aagctattaa tgaagctagt gaaaatttct ttattggtta attataacgt
     9361 atacattttt ctattatctt attaattcac cagatattaa aaaagagtgt ctcaaaatga
     9421 actttttagt tcataagaca ctcttttttt ataaaatcaa atatattttt attatttcaa
     9481 cactggaaaa aaggcttatc tctctatttt gagacaccct attaaatttt cataattctt
     9541 gcataaacat attaatctat cttcaataat tttttagctg attcactgta attatttctt
     9601 tttacaattt ccaaaactct atcaatctca tgttctgact ttgcacttac aaaaatcgcc
     9661 aattcttcat catctataat atcataacta tctacatatt tatctaaaca ttctaaaatt
     9721 ccatctttat tattataccc accaaatcta actactgcac tacactcatc ttctataagt
     9781 ccacttaaat ccaatttccc ttttgaaaaa gactttatat ttgaacttct attatctatt
     9841 atatctataa tatctgcata aacagcactt cctgttgcac ctcttccagc tcccttacct
     9901 acaaaagaaa gttcacctac tgaatcacct actaaaataa ctacgttgaa ctcattatct
     9961 atctttgaaa gcatattatt attgtccact aatgctggtc taacaaatcc acttacttct
    10021 cctgattcat acttacttct agcaaccaat tttatcttac aatttaattt ttttgcatat
    10081 tctatatctt tttcatctat tgaagttatt ccttctaata ataaatcttt ccaatatact
    10141 atttttccat aagataaagt agacaatata gataactttc tagcactatc atatcctaaa
    10201 acatctgcat ctggattaac ttctgcaaat cccaactctt gtgcctgttt taaagcgaca
    10261 tcatacggta aattttcatc atacatcttt gataatataa aattacaagt cccatttaaa
    10321 atagcgttta tgctctttat attgttgcct tccagtgatt ctatcaatgg ttttaaaact
    10381 ggaataccac ctgccacaga tgcttcaaac ttgatgctaa cattatttaa gttagctaat
    10441 tctataaggt cactaccttt ttcagccagt aaatctttat tagctgtcac tacatgtatt
    10501 tttttattta acgctcttgt tacataatca aaagctggat ttaatcctcc aattacttca
    10561 actagtatat caatatcctt gtcaaatata tcttctatat cagtagttat cttatcaaag
    10621 tacttcttat acttgtgttt ttctttattt ttaactaaaa ttccaacaac ttctatatct
    10681 ctttttgaag tattattttc tattaaatca attaatccac ttcctactgt tccataccct
    10741 aatattgcta tcttcactgt aacatacccc catcattttg attatattaa attatttata
    10801 tatataaata taccaataaa aaaagcttga gtataaactc aagccatatg acgggtttat
    10861 actcatcttt cagcataaat gctgcaggat ttagcaccaa tgtataatta aatatactgg
    10921 ttgccgggct tcacagggcc agtccctctg ccactcttga taagattgct aatttaaatt
    10981 tatgtttaat agtataatac aatttcttcc aattgtcact atttttttaa cttatttccc
    11041 taaaaggata taaactatta tctaacagct cttttagttg gtttaccctt ttttgtaaca
    11101 ttattatttt tagtctttgc tttcgcctgt tcatgtcctg gaaaaagtat tttaggctct
    11161 tcaatattcc tcttgtaaat agtaaattta aaaccaatag cctgcacaaa ttcagctctt
    11221 aaagcttcac atactgcatt agcagtttct ttagtatcaa gacctgcatt ttctaatata
    11281 gtaactttta ctaattctct agttcttaac ataccatcta attgctctaa gaaactctct
    11341 gtaacacctt ctttaccaat ttgtgtagta ggctttaaag tatttgccaa agatcttaaa
    11401 tacgcccttt gttttccttt taacatattc tcacctctat aattctatac ttaaattatc
    11461 tataatctat atttaaatta attgtaaaac tcaaattcta attcataaat tttaaccaca
    11521 tctccatctt ctattcccat ttctctaagc ctatcaaaaa caccttgact ctccatagct
    11581 ttttggaaat attgaaggga ttccatatca tcaaaattta cagaatacat tattcttcta
    11641 agtgctttac ctgtaactac atacacacca tcttcaatat ctatacttaa ctcttcttca
    11701 gtaccaatat caagttctgg tctatacatt tcttcttctg aaactagctc cacatcttct
    11761 acttctttta gcattttaga aacataggct attacttcat ctatgccttg acgagttgct
    11821 gctgacattt taaatactgt atatcctctg ccttctaatt cactcttaaa cttctcaaac
    11881 ttactctcat cttctaatat atcaaattta tttgcaacta caacttgtgg tctctttgaa
    11941 agcttttcat tgtacaattt aagctcatca tttatcttgt caaaatcttc aatagggtct
    12001 cttccctcta atccagatat atctacaata tgtatcaata cctttgttct ctcaacatgt
    12061 cttaagaact catgacctaa tcctatgcct tcagaagcac cctctataat tccaggtata
    12121 tctgcaagta caaaactatc tccaaactta gtttgaacaa cacctagatt tggtgtaagt
    12181 gttgtaaaat gatagtttgc aattttgggt ttagctttag ttacaactga tagaaatgtt
    12241 gatttaccta catttggaaa tcctaaaaga ccaacatctg ctatcatttt aagttcaaga
    12301 gttatccatc tttcttctcc atctgtacca gattttgcaa aagctggagc ttgtcttact
    12361 gcatttgcaa agtgttggtt acctttacca cctataccac cttttgcaac tatagctgta
    12421 tctccttctt tttttaaatc tgctaataca agacctgtag cctcatctct tattactgta
    12481 cctgctggta cttttaatac taaattttct ccatttttac cagctctttt tcctttgctt
    12541 ccgtcgccac cattttgagc ttgatatttt ttctggtact taaagtccat tagagttcta
    12601 agccccaaat caacttcaaa tatgatgctt gctccacgac caccatctcc accgtctgga
    12661 ccaccagctg gaacgtattt ttctcttcta aatgctaccg aaccatttcc accatttcca
    12721 gccttaacaa atattcttgc cttatctata aacaaattct tcacctactt aattaaaaac
    12781 ttttaattag cattaccaaa aataccatta taaattcatc agtattataa gaaaaaggag
    12841 tgcctcaaca ctccttttat gtatattact cagctatagc tactggatat atactaactt
    12901 tttttctctt cttgtctttt ctttcgaatt taacagtacc atcaactaat gcaaataaag
    12961 tatcatcact accttttcca acattagttc ctggatgtat tttagttcct ctttgtctaa
    13021 ctattatact tccagcagtt actaattgac catcgaatct cttaacacct aatcttttag
    13081 atatagaatc tctaccattt ttagaagaac ctaccccttt tttagatgct aataattgta
    13141 aattcatgtt taacatatgg agtcaccccc tactttttta aaatttttat attttttggg
    13201 tattcccgtt taatttcttt aaccgctaat tgaaagtgat ttagtaataa ttgtgcgtct
    13261 tttacatgtg tatctttgac tatacactct atatgacctt cttctcctac tactttttca
    13321 aattcaatct tttgtaattt gtctaaagaa tttataactg caatagcatt agatgtaact
    13381 gcagcacata ctatatcata gcctatttca gcaaaatcag catgtccctt taaacaaaaa
    13441 ccttgcaaca agaaatcatc attataataa tatttaactt ttatcataac ttaaccaata
    13501 actaagcgtt tattttttct acaactatct tagtgtatga ttgacgatgt ccttgttttc
    13561 ttctgtaatc tttttttgct ttatacttga aaactataac tttcttagct ttaccttgtt
    13621 caacaacttt agcttgaaca gatgctcctt ctactactgg agaacctaat tttaattctc
    13681 catctttaga gcaagctaat acttcgttta aagtaacaac atcacctgcg ttagcttcta
    13741 atttttcaac gaataataca tcaccttcag aaactttata ttgctttcca ccagtcttta
    13801 ctatagcgta cattaaatac acctcctcgg cctcaaactc gccagtacaa ggtacttcat
    13861 ttgaagattt aaacctttac tgtgcggcat tacaattatt aattataaaa tatttacatt
    13921 ttattgtcaa ctattttatc gaaaataaca ttggttttat tgtgctttaa tgtactattt
    13981 gcgtttaaag aaatctttat attatatttt tcaccaattt tatcaattat atccatataa
    14041 tattctttta tttgttcaaa aataaaatca ttaaattcta ccattatgtt tttgtaaaca
    14101 gtatgttcac ttattctcat aatttctttt tcaatactat ctagtatata atgtacagat
    14161 tttattgttt gttcaccatc acaacatgga caagacatta aataatactt atcaatggat
    14221 tctttttctc tacgcctagc aacttctact aaaccaagtt ttgtcatacc taatacttca
    14281 gcttttcttt tatctttatt aaattcttct tctaggatgt gtaaaatctc cttttgatgc
    14341 ttctttttat gcatatcaat aaaatcgatt attattatcc cagctatgtc tctaattcta
    14401 agctgtctta caatttcttt tgcagcttca agattagttt tataaacggt ttcatcaagt
    14461 ttaccagttc caataaactt acccgtattt acatctataa ccgtaagagc ttctgttttt
    14521 tcaattatta aataacctcc actctttaac catacttttt tatttaataa tttttctatt
    14581 ttagattcta ttctgtataa atcaaataca tctctatttt cctcaagaca cagtttatca
    14641 acataagtct tatctatacc tcttaaaata gacttaagtt cagagtactt atcataacta
    14701 ttggtaatta tagattcaat atcatcattc acattatctt ttacatattt agttgcaaaa
    14761 tctaaagact tatataataa tttcggacct ataccaagtt tatattcttt taaaatgttt
    14821 tcatacttta atttcaactc ttctatatct ttctttattt catcatgagt gcaaccttga
    14881 gcctcagtcc ttattattaa tcctagattt tccttattta ctgccttagt aatttttttt
    14941 aatctaaatc gttctttttc atcagtaatt ttatttgata ttgtagttct atcattggaa
    15001 ggtatataga caatatacct tccagaaata ctaatctcag tgtttaattt tgcgccttta
    15061 gttcctattt cttctttatt tatctgaacc aaaatatcct gaccagattt tatagtactt
    15121 ccctttttta attgtaaata agcaagtttc ttaaatccaa tatctacaaa acaagcttct
    15181 attcctggta taactttttt tacgattcca cgatatatat tggatacagt cttcttattt
    15241 aaattgtctt caacaaaaag ttctgttaat ctttcatctt caagtactgc tgttttctgg
    15301 gaccctatta gggactcaat aactatcttt ttcacaactt cacctctcga gcttacatag
    15361 gagtcactaa ttccccatct tctaatacat ataaatctct tctcaatata tcaacatcta
    15421 atgggtcaat atcaagttca aacatctcta atatctttgg tataagtata ttagtattta
    15481 aattagtttt tgagcctgta gctatagtag cagtaagagt aatatgttca tcttctaaat
    15541 ttaaaacatc aaaggttctt atcataggtc ttatatctac ttcaaccatc ttaccttttt
    15601 tattcttttt tgttatgatt atttctttat tattcataaa gtcaattact tttcttttta
    15661 caaactcttt cgtcataggt cttttcaaat ctatattaaa caaatattct ccatagtcta
    15721 tcacagaaga aagagaaggt gtttgtctat caatttcttt tgctttgata aaatctatcc
    15781 catctggaag ttgaattgat actttattta aaaattcctc tactgataaa tcatcttctt
    15841 ctatttcaat atctacatac tcaccttgac tttctgtccc taaagccaaa gcattgccat
    15901 aactcatttt agggtgagga ttaaatcctt gagaatgtga taagtttatt tcagctcttc
    15961 taaacgctct ttgtaacaat ctctgaaggt caagatgtga tatatatatc atgtcgcctt
    16021 cctttttaaa ttttactctt attatcttac tcatattagc aaagccccct tcctatatca
    16081 tgtatattta ttccacaacc attgcagtta tgtctacaat cagaagtgat tttttctttt
    16141 ttagcatttt cgtcttctct aattaagaat tttttactaa tacctacatc tatatggtcc
    16201 caaggaaata cctcttcata gtttctattt ctatgtgcat aaaaatctat agaaagatta
    16261 ttcttttcca tagcttcttt ccatatatct aaattaaaat gttctgccca tccatcaaat
    16321 ttagcaccta gtctaaatgc atcatatata acttttccta ttcttctatc gcctctagct
    16381 actactgctt ccatcaaact agtctttgaa tcatgataat tgtattttat attgttattt
    16441 cttaatttat ttactaaatg tctctgctta ttaataactt cttctgtagt atcttgacca
    16501 tgccattgga aaggtgtaaa tggctttggt acaaatgtag aagtactcac tgtaacacta
    16561 aaacttctct ttagctttcc tccatttact tttctataaa tatcaataac tttataagct
    16621 aatttagcta taccatctaa atcttcataa gtctcagttg gtaaaccaat cataaaatac
    16681 aacttaacac tattccaccc catctcaaaa gctctttctg ttgcattttc caaatcttct
    16741 tctgtaacac ctttatttat aacatctcta agtctttgag ttcctgcttc tggagcaaaa
    16801 gtaagtccag attttcttac ttgttgtatt ttatcagcaa tttccattga aaaattatct
    16861 aatctaaggg atggaagcga aatcccaata ttattagatg catattcatc taccaaataa
    16921 tcagtcaact ctgataactt actataatca ctcgtactaa gtgatgataa tgatatttca
    16981 tcatatccag tattcttaac taatttatct aatatttctt taagtctttt aacactcttt
    17041 tctcttattg gtctgtatat catacctgct tgacagaatc tacatcctct agtacatcct
    17101 ctaaataatt ctagtactat tctatcatga acagtatcta tataaggtac tattagtttt
    17161 tctggataat ctacagtctc aacatctttt attatccttt tagtaggatt tttagtaatc
    17221 ccttctctat taggagttac actttgaact gtaccatctt cattgtactt gacatcataa
    17281 aaacttggta tgtatactcc ttctatgcta gatattttat ataaaaaatc ttctctagtc
    17341 gttttatttt tcttccattc tttatactca tttactactt ctaaattaac ctcttcacct
    17401 tcacctaata ttactacatc tacaaaatct gctaatggtt cggaattata agcacaagga
    17461 ccaccaacca ttataaatgg gtcttccaaa gttctttctt cttttaatat tggtatattg
    17521 gctaaatcta atatatttaa gatattagtg tatgaaagtt catattgaag tgtaaaagtg
    17581 acaaaatcaa agtttgttat aggctctctt gactctaatg caaataatgg tatacttttt
    17641 tctctcatta tattttccat atcaactgca ggagaataca ctctctcaca aaatacatct
    17701 tcatccttat ttattacatc atataatata tgactcccta agtgactcat accaacttca
    17761 tataaatctg gaaagcaatg tgcatatctt atcaattcac tattactagt atctttatga
    17821 attgaattta tttcatttcc aagatatcta gcaggctttt ctactttttt taagattttt
    17881 ttcaagtcta ctttattcat ttattaaaat tcctccaaac aagctcttta tttttattct
    17941 tatttataag taatattata cacgataaaa tattttctat caaaaatata actaaaatat
    18001 tgaatttaaa atacatatta ttcacaaaat agaatagcta aaaatattta agaatatttt
    18061 ctattaaatt tttattgaaa tacaattttt ttacaaagta tgatatatta taaacataaa
    18121 actattgttt tacatgactt atcatgacat cttttgtttc attcacctca aaatggggta
    18181 tgttacttat ataatgataa attttaggag ggttaaaaat gagtaaagtt tttgaagtaa
    18241 aaaaagatat ctactttact ggagtagtag atgaaggttt aaaagtattc gacataataa
    18301 tggaaactga gtttgggaca acttacaact cttatttaat caaggacgaa aaaacggttt
    18361 tatttgacac tgtaaaggca aattttaaag atgagttttt aagtaattta tcagaggtta
    18421 ctgatatagc taaaattgac tatgttgtaa ttcatcacac agaaccagac catgcaggta
    18481 gtttaaaata cttattagat ataaatccta atatagaagt ttattgtact aaagctgcta
    18541 aactatactt agatggtcaa ataaatagac cttttaactg tcatgtaata aaagatggtg
    18601 aaattttaaa tatcggtaaa agaaatctta gatttataac tgctccattc ttacattggg
    18661 ttgatacaat gtttacttac attgaggagg acaagactct tttaacttgt gatgcatttg
    18721 gttgtcactt tgcaagtgtt gatgcagagg tagtgaatag tgaagattat ctaaaatcag
    18781 ctaaacacta ctatgattgt atagttaagc catttgctaa acatgtttta agtgctgtag
    18841 ataaggtggt aggactaaac atagaatttg atactatatt gacttctcat ggtccaatgc
    18901 ttactaaaga cccaatggct gctgttaaaa gatatgttga gtggtctaca gaagctgtta
    18961 atacaactaa tcaaaatcaa gtttctatat tctacttatc agcttatagt aatactttag
    19021 agatggctaa aaagataaaa gaaggacttg ataaagaagg tgcaaaggct gaattatatg
    19081 atttagaaga tatgacatta acagaaatgc acgatacatt agtagtgtca aaagtaatat
    19141 tactaggttc tccaactata aacaaaacta tggttaaacc tatgtgggat ttattctctg
    19201 ttatagaccc aatggctaac caaggcaaga tagcaggagt atttggttca tttggttgga
    19261 gtggtgaagg tataactatg gctgagactt tacttaaatc tatgtcattc aaaatgcctg
    19321 tagaatctct taagaaaaaa ttcttcccta gtgaagagac attaaaagag tgtatggcat
    19381 ttggtgcaga atttgcaaaa ttagttaaat agccattaat caaacataat attatttaaa
    19441 ataaatgatt ttatatttaa aaataaatta aaatggagtt gtctcaaaat taatttttct
    19501 aatctaattt taagttcaac tcctttttta ttttctaaaa tgactgatat aatgataaat
    19561 gcaccctttg tgcgagggtg cattatttat aatatgttct atttgtacac tagtatattt
    19621 gtattaattc acatatctag cgtatgctac catccctctt ccagaattag atgccgtttc
    19681 accaatttcc actttaataa ttacattatt ttctttacac ttttttgata attctgctgc
    19741 agaaaggttc ttaccagtaa aatctaaaga aaatggctta tcatattcaa aaggatactc
    19801 atcaggtaca ccatctggag ctaatgcaac cataccatat ggtgtattca taaaccctat
    19861 tacagtaact gtatgctttg atgggtctaa atttgaattt ttgcttgtaa acttaattgt
    19921 atttattgat gagttgatta aactacacgg aactccctca tacatttcaa tttttggacg
    19981 tagattattt ccataaactt catcaagtat tgccccttgt tgatctgcta tcatagtgtg
    20041 attcccaggt ccaactggcg cagaaggctt agctggcgta ggtttcttaa cagttggcgt
    20101 tggattctgt gtctttacta cttcgccaac agctggatat gctttcttgt caaatggtaa
    20161 tgggtgagta agactcttgt atatgatgtc tgctcctgct gatttgttgg catcaatatc
    20221 tacatgatac aaacgtccat cctcaaaacg aataagattc cactgatggt catttgttgt
    20281 actatgtaca taataacatt caattcccat agcatcacat aaagctttca agctcctaca
    20341 cattccagaa caagcacctt ttttagtaac caatgtataa gcagtattgg ctccctctgc
    20401 tgcgttccag ttaacatatg ttgtgttgtt tttaatgtga ttataagcaa ccctaatctt
    20461 agcatctgtg gtcatgttct ttgtaatttt cttgttcata aagtctgctg ttgcttgtgc
    20521 taccgaatta agttgagctt gtgataactt tggaccatat atactgttgg ttccagctac
    20581 ataacttttc ggtgtctttg cagtaacatc tttagctgtc ataccataaa ctgttacact
    20641 catacatgag gttaaaacca tcattgcaat caatagttta gtagctaatt tcctgatttt
    20701 tttcatatta gcattctcct ttataatata ttttactttc aattccctac cattaattaa
    20761 gttcatttta gatttaaaat atggattatc aacatgtatg catagcaatt cacgtggtca
    20821 tagaatattt agatttcttg gaaaatctgt tctatatttc ctatatagtt cgtatacaat
    20881 ccaactcaca aacctgcatt tttgatatca tcacaataaa atgataataa ttaatatatt
    20941 caaaaatgtt ggtctgtaac aggtatgtca attttccaat tattggtaat ggcgagagtg
    21001 aggagaattg tcaataatac atttaaaatt aaaattgtat acacttcata cattctcccc
    21061 taacaacatt atacagatta taatttgtat attcaataca ttttttggaa agtataatta
    21121 tatcaaaata tgtgattatg tatagataca atccactatg gagaaatata aaagaaaaga
    21181 gtataacaaa caataaaaaa taagatgatt caaattttat tttgaaacat cttatttact
    21241 ctacaaatta agattatttg gtgaattatt taattattat tttttattaa agaaatttta
    21301 aatcttaata taaaatacgc tattatacat aataatccaa atgcaaatgc tactggaatt
    21361 aacatctccg attcaaaata aaagaaatat tctaagaaaa tatctggatt tactatattc
    21421 ccattcttgt ctaaaaaatc ttttccatta tatcctaaat gctgtataaa attacttatg
    21481 ttattataat ctgcttccct ctcatatacc atattagcat tcaatccaga agaacttaaa
    21541 ttagtgtttc catctttcat atctattaca tatagtctaa gagctttgac tttactatac
    21601 ttatctttat caagtatttt ttcaagttct aacttatatt caccaatctt tgtcatatca
    21661 tgtctttctg ccaattgctt tatttctcca tcaagttctt ttcctaaatt atacatatta
    21721 tgttgtaaac tattattgta ataccacata aatccagaaa ttaaaaatgc aattatactt
    21781 atgtaaccta atactttttt aaaccccatt acaattgatt tatgcctatc caatgataaa
    21841 gatagttctt ttattatatt acataattca tactgcattt catcaccatc atcaaatctt
    21901 tcaattgctt ttttacatgc ttcttcttca tctaatcctt ctaatttaaa ttcatttgca
    21961 gattctataa gatggcatct catttcctgt tttaattcta tagtactttt attgtcacat
    22021 tttttatata gtttatctaa atattcatct attagtttca taaattaatc cacctctccc
    22081 aaaaattgat tcataacctt tttaataaat ctccattctt gtttctttat ttctaaaaaa
    22141 tctttacctt cattagttaa attataatat tttcttcttc cacctgaact ttgttcattg
    22201 ctataataag atttaattaa atttttagat tccattcttt taagtgcaag atacattgtt
    22261 ccttctttta attcaaactc acttctttct cttacttgct ttgcaatttc atatccataa
    22321 caatctttct tttctaatat agaaacaatt aatatatcga tataaccttt taacacttct
    22381 ttatttaact gcattatgta ccaccgcctt ttcacctact actctataat gtatagtact
    22441 tatatttact ataatattac atagtactct atattgcaag gtttatattc tacaatagac
    22501 ttaaaaataa taaatagctg tatattaata tttaatctat aaatactaat atacagctat
    22561 ttatcaaatt ttaaaaataa atttttgttt tattaatgtt gtcataacaa catttacttg
    22621 gttgaaatag tattacctat aagtttaaat atatataata atagacttga ttctatttca
    22681 tattattaaa atagagtaat agtttaaatt ctactactct atctataatc tatttcctaa
    22741 ttatttaatc tcaaatttag ctcttcatca tttaaatctt tcataagatt tctacaggta
    22801 ctagatttat tccaacagaa agactagggc attaaacact tatatatctg tttctttaga
    22861 ctgtaatatt aatatttttt aaatacgttg acttttgctt tttctaactt ctctccatga
    22921 tagttctcct ctatcaagag cttttataaa tatttctgct gaagctagat ttgtagctat
    22981 tggaacatga taaacatcac aaagtcttat taacgcttgt atatctgttt catgagcctg
    23041 agatgtcaat gggtctctta aaaaaataac taaatctatt tcttgtgtta ctattaaaga
    23101 acctatttgt tggtctccac ctaaaggacc agatgctaat ctatttatat ttaattcagt
    23161 ttcatccatt attctttttc ctgtagttcc agttgcatat agtccatact tttttaaaat
    23221 tgattcataa cctatacaaa atccgaccat agtgtttttc atttggtcat gtgctactaa
    23281 tgctatattc atatatctaa tctcctcaat ttatgtttag atgtatttaa atttagaaat
    23341 ttattttctt tcttctcata cacacattta gtactaatcc taagtttgct aaagatgtca
    23401 ataacgaact tcctccataa cttacaaaag gtaatgttac tccagttact ggtattaacg
    23461 caaccgtcat acctatattt tggattatct ggtaaccaaa cattcccata acaccaacca
    23521 ctatgagggt tccataaaaa tcttttgcat ctcttgcaat tgctaaaagc cttaatagga
    23581 atatcataaa taagattatc aacactgcca ttcctattac accaagttct tcacctacaa
    23641 cagcaaatat aaaatcacta tcttgtacag gtaaaaaatc ttcttgattt tgacttccat
    23701 tgtaaagtcc tttaccagtt acgcctccag aaccaattgc aatcagagat tgcataactt
    23761 gatagtttcc ttttagagtt acatcttctg gatttagaaa agcttctatt cttacctttt
    23821 gatggtctgc catcattaaa tacatcagtg gcattgacac taatagtatg attattcctc
    23881 tttttatcaa ctttgagcta agacctgctg tgaacagcat tgcaaatatc atacaacaaa
    23941 atacaattcc tgttcccaag tctggttgtg caatcaataa tccgataaat ggaagagaat
    24001 aaactacaac aggcataact tcctttaacg tatttaattt atcctttttg gattcaagta
    24061 tctttgcata acttagtaca aatgttaatt tgactatttc agatgtctgc aagtcaagtg
    24121 gtcctaagtt aatccacgac ctagctccac cttttactgt cccaattcca ggtaataaaa
    24181 ctatggctaa caaaataaga cttattatat aaagcgcttt ataatacctg cctagaaggt
    24241 tatagtcaaa aaataatatg actataatca ttcctatccc aagtacaaaa gctaatcctt
    24301 gtttaatcaa ttgattatat gaacctgttg aattagcatg tgttgcacta ctaagtataa
    24361 caagcccaaa aataaagata gctaatactg taactataag tttccagtct aactgtttta
    24421 tcaacttaat tgtcgactta taattaatat tgattttttt caaagaatca ccgtctttct
    24481 atctttaaac atataattaa ataaaagggg catataccaa taaggatatc ccccttttaa
    24541 gcactaatta catacatcta tcttttatat tctttagtgg tatattagca actaatgcag
    24601 atacaggttt gtcatcatgc tcacctctgc atttagacat ttttatttca agaccatcat
    24661 cttctatttc tgcataatta gctattactt ttaaaatgtc tgtttttatc atctctaaaa
    24721 gttgtggtga acaatctact ctatcatgaa ctaaaactag ctttaacctc tctttagcaa
    24781 cagatttact agttttagcc tcgttagaaa aaactctaaa taaatctaac acagatgtat
    24841 cctcctttgc tacttagcca tgctaaacat ttttttaagt ctaccaaaga atccatcttc
    24901 aacttcaaga tcaagtagag gaacttcttc atttagtatc ctttttgcga tatttttgta
    24961 tgcttgacca gcaagtgact tagaatcaag tatagctggc tctcctttat ttgttgatat
    25021 aattatgctt tcatcatcag gaacaagacc taacaaatct attgctaata tttctattat
    25081 atcttgttta tccatcatgt ctccacgctt aaccatatca tttctaattc tatttataac
    25141 taatcttatc tcttttattt catttgcttc taatagacct attattctat cagcatctct
    25201 tactgctgat atttctggat tagtaactac aatagctcta tctgccccag ctactgcatt
    25261 tttaaagcct tgctcaatac ctgctggaca atctattatt atatactcga aagattcttt
    25321 tagtttctca cacaggtcaa tcatctgctc aactgagaca gcatttttat ctctagtttg
    25381 tgctgctggt aataaatata gattatcaaa tcttttgtct tttattagag cttgcttaag
    25441 cctacaagtt ccttcaacta catctactat gtcataaact attcgatttt caagacccat
    25501 tactacatct aagtttctaa gtccaatatc tgcatccaca actactgttt ttttattttc
    25561 taggcttagc gcagttccta agtttgctgc ggtagtagtt tttccaaccc cacctttacc
    25621 agatgttata actataactt cgctcataat actaccccct atttttcttt ctatttgtct
    25681 aactttgaca aatagctttc gattacaatt cttccattac ttacaaaggc tatttctggg
    25741 ctaatttctg attcactttc ataattttct tcatcatctg gagcttctgc aatattatct
    25801 gctatttgta atattttagg attaagattt ccagcaacaa catatgcaaa ttcattgcct
    25861 tctgcacctg catgtacaaa accttctatt ttacccatta caaaaacatt acctcctgct
    25921 acaaccttag caccagcatt tatatctccc ataacaactg tatttgattt tgaaaggact
    25981 tttgaaccag gtttcatatc attcaatata actacatcac cttcaaattc aatattttca
    26041 ccagatctta gggtattgac atattttgtt ggaaaattac tattttcttc aattttttga
    26101 tcttcaacaa attccacatc aaatctagaa gtaattcctt ctttaagttc tagaatctcc
    26161 atgtcagtta aacaatcact attaatttta ctaattttag ccccattaaa aaagccaaca
    26221 tatgcttcca atttgtttat tattttttcc tgtatttcct caaatggagc ttctcttttt
    26281 atatttacta ttatccctct tttattaccc ttgaactcta ctagttcttg actacaaatt
    26341 tctcttaaag acataacaac ctccagagtg atatatcatt tatattcttc aaatacgctt
    26401 taaacccttt tattttttct atataaagct aaagtttata catagattga gctatctatt
    26461 aatttgtgac tcgaaattta tattttcgtc agaagaattg ttaacatcat tcgtcttgtt
    26521 gtcattttta ctattagttg gctctaatcc catataagtt ccaataactt ctctagttgg
    26581 taaaagtgag aatacacttg aatcaccttg aggaattaca catacaacag ctatttctgg
    26641 gtcatctgct ggagcaaaag caacagtcca cgtaaaagaa ccataatctt gtttaaatct
    26701 atctatttgg tcatctgtta tttttggatt taattctttt atagcttttc ttagatatga
    26761 agaattcacc ttatcagtgt cctctaatct aacttttact ccatcttcta attcttcctc
    26821 taatttcttt ctttcttcgt ctttcaaatc tttattttct aatttctttt ttatttcctt
    26881 ttccttagct aatgaaagct ctttttcttt ttctgctttc atcttatcag ctagtttaat
    26941 cgcatcattt aggttgacat tataagatga catatgactt tttaaatatt catactcgtt
    27001 atctgtaggt attttcccac ttttctcagc tgtaccagtt tttgctgcta catctattgg
    27061 aaaatcagca aaagcactct tcgctgtacc ttgtcttgca accaatttca taccttttgt
    27121 taattctttt aagttatctg gatttttaaa aggtattttt tcgactttct tctggtcatt
    27181 aattttaact gatgaataat cacttgaaac agctctatca actacagata attctactaa
    27241 attacctcca tttgctatag cagctacata tcttgatatt tgagctggtg tataagcatt
    27301 ttcaccttgt cctatagcta agttgaatgt atctgcagta ctccattttg caaaattaaa
    27361 ataactaaat actgctaaat ctgctacttc ttcaattcta tcttctttaa catccaattt
    27421 ttttagccta ttcattgttt caactctacc aggagttttc ttttctgctg cccagcttac
    27481 aatctcattg attcttttct catattcttt aggatttttt tctctagtta tatcaacaaa
    27541 atcatttgcc atttctcttt ctaaatttga ctttagaaga gcttgtgttg atttcaattt
    27601 atcttctgtg ctaggaactt tacctgctct ttcttctact tcatcttgaa gccctgtatt
    27661 ttggtcaagc ccaaataatt ttgcatactc aagtatttta tttgcattca tatctatacc
    27721 aatgcttttt ccatctggcc atgttttacc tgtaccaatt gttgccatat atatattaca
    27781 agactcttgt attgctttat ataagtttgt cataccatgg tttcctctac catggttcca
    27841 tacatagtca ccaaaagatt ttttacctaa cattataacc ccagggtcat ttatagtaaa
    27901 gtttggatcc agaccatttt ctaacgctgc cattgaagtt accatcttaa atgaagaacc
    27961 tggctgaaat tccccttgtg taaccaagtt taaaagtgga cttcctgcta gtaagtcatt
    28021 tggatttttt ggttgaagtg ctttataatc ctctgtagaa ataccttttg caaatttatt
    28081 tgggtcataa ttaggataac ttgatgaagc taatacttct ccatttttaa catcaatagc
    28141 tataagagct gctgactgtg cttttcctgc atatgcacta attggtttgt ccccaaattt
    28201 acttttaaaa gtacctcctt tagaagcaac ttcgattatc tgttttaatg cattatctga
    28261 aacttcttgt aaatctttat ctagtgtaag atacacagta tctcctgatt taggtttttt
    28321 agattcaatt tctttactga ttctacccaa tgcatcaact ttaaccattt tataaccatc
    28381 agttcctctt aatctacttt cattactctt ttctactcct gcaagaccta ccatatctcc
    28441 agtttcataa cctttttgaa ggtatgattc tatttgagtg gatggcattt ttcctacata
    28501 tcctaacata tgagaagcta atgacccatt aggataatat cttactggtt ctactgctat
    28561 tgaaacacca acaaggtcca tagcactttc ttcaatttga gcaatcgtag tttctcccac
    28621 atccttagca atagttactg gattatattg agaatatcct tttgatttta tcaaatccct
    28681 tacgaccatt atttttcttg catcttcatc actcaaactt ttatcaattt ctaatgcatc
    28741 actatttctt actttttcaa acgcttcttt ggcactcagt ttagtttctt ttatcttata
    28801 actagccaac caatctctct tatctctttc tgctgtgaac atccatttac taactaaaat
    28861 aggtggataa tatccatttt catttagttt tgcctgtaat cttgtcgcat ccaatctttt
    28921 atcttcttga gataatattc cagctgatat aagtttgtcc accaagtaat aaaaactttc
    28981 cttagcatta taatcatttg gaataccatt ttctgattta tattccctaa tatctctgtc
    29041 atatgtataa tagtactttc cattttctac atatatagga aactcatcta catattcttc
    29101 accatttctc tccagcaaat ttataagttt taatgatatt tcatttgctc ttgaatgctt
    29161 atttgcatct ttcttattaa tatcgttacc tgaaacttga acagtaaata agtttttatt
    29221 tcctgccaac agtcttccat atctatcttt tatttctcct cttggagctt ctattgccaa
    29281 ctttttatat gttttattct cagctaactc attgtaatat tcatatttaa atgtagtcat
    29341 atagattatt tttactaaaa tagctaaaaa tatcacgccc atgactatct taattatttt
    29401 tagtctatca acttgtttat tttcttccat gaaatcacca actaatcttc tttaagtttt
    29461 aaaactgctc ttttagataa gcgatatatt actaaaccaa ttaaactatt cactattggt
    29521 gctactagta gaccttttac aaaaagtgtt gatatgttgt agctttgata aattatacta
    29581 gatgtaccta tattgacaat tgaatcaatt aaactgccta taaaaattaa aacgaaagta
    29641 ataatataac tacctttata tagctgatct ctcatgtatc caattgcata tgcaataata
    29701 aacaaaatta atgcatttac accaaaaatt ccaccaacgg ttatgtcttt aataagccct
    29761 attattgctg ctataatccc accttctaat tcatctaaat aaagagagat tatggttaca
    29821 tatataagaa ctaaattaaa gcttatgcca aaaatatcta tataatttgt tatactattt
    29881 tctatagtca taagcacaat ccccaacaga caaagtaaaa cttttttcat tgtttttatc
    29941 ccctttatcc tatatttctt ggttctatga ctacaacgtc atttatattc ttaaaatcaa
    30001 cataaggttt tacaactaca tattttaatg acttatcttt atcatcaacc actttttcaa
    30061 cttcgccaat tggtatacca tctgggaaga atccaagacc tgatgttgtt attatatctc
    30121 cttgaattac attatatgat gagtcaaaca tatatccttg caaatatcct ttactattat
    30181 aactatcttt attatctaaa gtagtatttt gagtaattgt acctttagca ttggcatcct
    30241 ttgctagttt aaagcttaca gatgccttag aatccaatag tgaaattgcc ttactataat
    30301 tgttggaaac ctcataaact atgccaacta atccactacc attcataact atactttctt
    30361 tttttacacc tgaatttttt cctgcaccta tgacaaaact ctcataccag tttccatcat
    30421 ttttaccaac aacacttgct gaaatacttg tcgccttata ctcttcttgt acaaagttca
    30481 gtgtcttttt taactcttct agcgattctg ttttatctag tttggcattt aaagctatca
    30541 tatttttttt aagtttttca ttttcttctt ctaatttttt taccttttta gaattatctt
    30601 taaaatttgc tacatcttta aaaccatttt tgataaaaga aaatccatca tttattccct
    30661 tacctacact tgtaatagca tctgaagcta ctcctaaatt tactggacta ccactagaaa
    30721 atttaccaat tgatataccc acaattccaa ttaaagtgat agcaactacg cccgttgcta
    30781 tcactttaac attaatcctt tttttctcat ttttgttctt gtcaaatctc aaggccatca
    30841 ccaacttcta attcttagta ttcatcatta atactttttc aaagatttct tggtcttcaa
    30901 cagatttacc tgttccaagt gcaacacaat caagaggtgt ttctgctatt tgtacagaca
    30961 taccagtttc ctgtgtaata agcttatcaa gacctctaag caaagcgcct cctcctgtta
    31021 gcattattcc gttttccatt atatctgagg ctaattctgg tggagttctt tctagtgtag
    31081 attttattgc atctactatt gaacttacag gttcttttaa tgcttctcta acttctgtag
    31141 agcatatttc tattgtttta ggtaatcctg agattaaatc tctacctctt atttgcatat
    31201 ttatttcttc atcatcttta aatgtagaac ctatgttaat ttttacattt tcagcagttc
    31261 tttcacctat cataagatta tattcttttt ttacataagc cactatagac tcgtcaaatt
    31321 cgtctccacc tattcttata gatttagcag taacgattcc tcctaaagat attacagcta
    31381 tttctgaagt acctccacca atatcaacta ccatattacc ttctggttct tcaactttta
    31441 atccagcccc tatagccgct gccattggct cttctataag gaatgcatct ttagctcctg
    31501 cttgtcttgc agcctcttct atagctctct tttctacttc tgtaactcca aaaggaacac
    31561 atatagctat tcttggactt acaacacctt ttttatcagc cgctttttgt ataaaatagc
    31621 taatcattga ttgagttatg tcaaaatcag ctattactcc atctttcata ggtcttatag
    31681 ctactatatt tcctggtgtt ctccctatca tttttttggc ttcttcacct actgctaata
    31741 cctctttact atcatctctt attgcgacaa ctgatggttc tctaacaaca ataccttgtc
    31801 cttttatgta aactaatgta tttgcagtcc ctaaatctat tcccatatcc tttgtcatct
    31861 tattaaaact aaaaaaacct tttttttctt tctttttttc cttagccatg attttactcc
    31921 ttcctactat taagaatcat gtttaaaaca ttctcctatt attttatcac atataaagtc
    31981 aaattatcat attttcttta aagctaaagt ataatccatc tccaataatt atatggtcta
    32041 ttatttctat tccaattatt tctccacatt taataagtct tgatgtgata tttttatctt
    32101 ctcttgatgg ttctacactt cctgaagggt gattatgcat cactattatc ttacttgcac
    32161 ttcttcttat agcttcttta aaaacctctc ttggatggac taatgacgag cttaaagtcc
    32221 ctatagatac atctacatca gatattatct cattttttgt gtttaaaaga accgctttaa
    32281 aaacctcttt ttttaaatac cttaggctat ccatataata cctctgtata tcccaaggat
    32341 tccttatttt atactttata ggtttaaaac tagctactct agagcctagt tctaaagctg
    32401 ctttaatttg ggttgatttt gataacccaa ttccatctat attacacagc tcctctattg
    32461 tcatatcttc taaatgtcta ataccctgaa tatctctatt tattatatag ttggctaatt
    32521 caatagcatt tttattcttg ttgccagttc ttaaaagtat agccaacaac tcagcatttg
    32581 ataagctttt tacgcctttg gcaagcatct tttctctggg tctttcctct ggtgccattt
    32641 cttttacctt aatggttgaa ttaaatgact ttttcagata aatcacactc cataaaaaag
    32701 atttatacta aaatattttt ttaataggtc gcctaacctt gaaattggaa gaccaactat
    32761 attaaaataa tctcctctaa tttcttcaac taacaaagct ccataaccct gtataccata
    32821 ggctcctgct ttgtcaaatg actcattagt tttcagataa tcctcaatat cctgctctga
    32881 taacgtttta aatttcacat tgctgattac atagtcaatt acctttttat cttcgcacaa
    32941 gtttattaag ctaatacctg ttatgacttg atgctctctt ccagatagtc tttttaacat
    33001 atctcttgca caagactcat cttttggttt tcctaaaata gcattgtcta aaacaacaac
    33061 tgtatcagct ccaataacaa catcttcatt atgttcagat gctacagaca tacttttttc
    33121 aaaagctaat ctcataacta aatgttttgg tgtttcacct tccaatataa tctcatcaat
    33181 ttcattttta attatatcaa atcttacatt cgtattctct agaatttctt tccttcttgg
    33241 agaggctgat gccaagatta tattcattta ttcacctcat ttgtacgtaa tttgtaccta
    33301 tttagtctat cactatattg taaaaaattc aacagaaatg tcgaaccttt tttgttacac
    33361 tattgttata tttattacca ttagaataaa tatacataaa atagaggtat ggaaattatt
    33421 ccatacctct gttttatgta ctcattagag atatggaaat tattccatat ccttattttg
    33481 tccatattac aaaattttaa tagctttctt tggacatttt tccatacata aatggcatcc
    33541 tacacattta tctgcatcta ccttatgttt ttcttttaat tctccctcta ttgcatcaaa
    33601 cttacattgt tttttgcaca ctgtacatcc aacacaaagt tcttggtcaa tagtaacttt
    33661 ctttttctta gttatgtcac ctgatattac ttttgtaggg cattttgcta cacattgcat
    33721 acaacctaca cacttattag ggtctatctt agctattttg tcttcaaata ttattgcatc
    33781 aaatttacaa gcttttacac acattccaca gccaatacat ccagcagtac atttttcttt
    33841 aacagcttta ccaaactctt tgctattaca ctctacaact acttcttgac tttctggttt
    33901 tgtgattatt atacccttag gacaaacttc tttacatttt ccacaattta cacacttttc
    33961 ttcatctatt actgctattc catcaactat agaaatagca tcaaatttac aagcatcttt
    34021 acatgttcca agacctaaac atccaaattt acacatctta gcacctgagt ttaaaacatt
    34081 tgctgctcta caatctgata ttccttcata ctcatattta tcttttgcac ttgaacaagt
    34141 tcctttacaa ataacttttg ctacttgttt ctcacctgct tcagcactta ttcccattat
    34201 ttctccaact tttgcaccaa catctgctcc acctacaggg caaccattaa ctggtgcatt
    34261 gccttcaact atcgcatttg caagacctcc acaacctgga aatccacaac ctccacagtt
    34321 ggctcctgga agtactccta gtatagcttc cactctctcg tctacttcta cagcaaactt
    34381 tttagatgca aaatctagta ctatcccgaa gattaagccc ataattccta aaactaatac
    34441 agctgtaagt atcaccattt tcacccctct tttttatagc tttataagtc ctgtaaatcc
    34501 taagaaagct attgacatta aacctgctga tataagcgtt atagggaaac ctttaaatgc
    34561 ttctggtata tcagctaatt ctagtctttc tcttatacct gcgaatatta ctattgctaa
    34621 agtaaatcca gctccggctc caaatccgtt tattattgtt tctactaaat tataactttt
    34681 ttgaacatta actagagcta taccaagaac tgcacagttt gtagttataa gaggtaaata
    34741 aactcctaat gcttgatata aagatggact catcttttga attaccattt caacgaactg
    34801 aactatagaa gctataacca atataaaagc tattgtttgt aagaatccag ttccagtttt
    34861 tactaataaa atctgtataa aataagttat aattgaagct agagttaaaa cgaacgtaac
    34921 tgcaactccc atccctactg ctgtatcaac cttcttagaa actcccaaga aaggacatat
    34981 acccaagaat tgagatgtta taacgttatt aacaagaacg atacttaaaa ataaaagtat
    35041 taaattcatt tattacacct ccactatgct tttttacttc ttaatttatt aaatcctgca
    35101 aataagaatc ctaatgttaa gaatgcacct ggtggtaata taaatattaa tactggttgg
    35161 aaagatgctc caaataatgt cattccaaat aaactaccat ttccaagtaa ttctcttact
    35221 gcacctatta ttgtaagtgc aacagtaaat ccaagacctt gacctacacc atcaactatt
    35281 gaaggcatag ctcctgtttt gaaagcaaaa ctttctgcac gagctaatat taaacagtta
    35341 acaactatta atggtatata tataccaaga gccttatcaa gagcaggaac atatgctttt
    35401 aaaagcatac ctactattgt aacaaatgta gctataacta ctataaatat aggtattctt
    35461 atcttatctg gtgtaatttt tcttattaaa gatataacta aatttgcaca tattaaaact
    35521 gctgctgttg aaagacccat accaattcca tttattgctg aagttgtaac ggctagtgtt
    35581 ggacacatac ctataacttg aacaaatgtt gggttctcat ctattagccc atttttaaat
    35641 actttagcta aattcataat taaccctcct tatttattaa gagcactatt gaaaacatct
    35701 atagcagcat ttactcctgt agtaactgct gtagatgtaa tagttgcacc tgatattgct
    35761 aatatttgat tatctgctgt tgtacttcct tttgctactt caagaggctc agcagttttt
    35821 cctttgtatt gacccttaaa tgcatcatcc ttagcttttg ctccaagacc tgctgtttct
    35881 gacatattac caatgtcaac acctgtaact tgaccttcag atgatatacc taccataact
    35941 tcaatttctc caccatatcc acttggttta gcttttaaag tatatccaac cacttcagaa
    36001 ccatctaaac cttcatacac ttcagctata agaccatctc caaggccttt gtaagtatct
    36061 tccttcattt ctttaaattc ttttgcttct ggaaggactg cttttctaag ttcattattt
    36121 gcttgtatat ttctttgttc tattactgga gctgtaacct gattagtagc tccaagagct
    36181 aatgcagcta ttgcacttat agcaagtaaa gtaccaccta atctcaccat actgttcatt
    36241 atttagccac ctccccaaat actctatttc taacaaactt atctataagt ggagcaagac
    36301 agttcactaa tagtattgag taagatacac cttctggata tccaccatac attcttataa
    36361 cagttgttat aagaccagct aatacagcgt atattatttg acctttttta gtcataggcg
    36421 aagttgtata atccgtaagc atgaagaatc cacctaacat aagtcctcca gcaaacagtt
    36481 gatatattgc gaaagttata ttaaatccac ctaaaaggaa tgttaatata aatacagttg
    36541 ctatgtaaaa tactggtata acataattta ttatgccttt atacattagg tatactccac
    36601 ctaataataa taatattgct gatgtctcac ctatacatcc accaatattc cctatcatca
    36661 tgtcagcaag actaattcca ttgctagaaa tatctgccag tcctgctgct ccatttttca
    36721 aaaagcttaa tggagttgct gtagtaactg catctaaatt tttacctatc cagttaacac
    36781 ctggttgagt ccaagcagtc attgctactg ggaatgatgc taataaaaat gctcttgcag
    36841 caagtgctgg attgacaaag ttacatccaa ttccaccaaa taccatttta actactaata
    36901 ttgcaaatat tcctcctact agacacatcc accaaggaag tgatgctggt acgttaaatg
    36961 ctaataataa tcctgttaca acagctgaaa aatctcctat agtacttttt tgcttcgtaa
    37021 atttttgata taaaaattca gtacctactg taccaagtat acaaaaaaac atagcactca
    37081 aagcattaag tctaaagaag tatactcctg ctactgctgc tggaaggagt gctataataa
    37141 cttgtttcat tatatatgaa gtatcttcat tacttctcac atgaggagaa gatgatacta
    37201 tcaacttatt ttccatcgtt tttccccctt aactttcttt atttctgagc agcttgcttt
    37261 cttctctttg ctcctatttc tctctttgct gatcttatag attgaagtaa tggtcttctt
    37321 gctggacaaa taaatgagca agacccacat tctatacaat ccattgctct atgatattca
    37381 gctgtgtcat agtcatcttt taaagaatat gcacttatga aaagtggttg taagaatgat
    37441 ggacatacat ctgtacatct tccacatctt aaacagtttt gaatatctgg agtacgtgat
    37501 tcttcctcat ccaaacataa aattcctgaa gaacctttgt tagtcgctat ttcagtagta
    37561 tattgagcta ttcccatcat aggtccaccc attataacct taccaatctt cttatcttct
    37621 ttaaatccac cacattgttc tattatttct gaaactaatg ttccaacttt tgttattagg
    37681 ttctttggct ctttgatgca actacctgtt attgtagtga ttctttcaac caaaggcata
    37741 cctgttttaa tagacttagc tatctgtgct gctgtggcaa cgttgtcaac aactgcacct
    37801 gctgctattg gtaatccacc agatggaact tctttgcctg tacacgcata aataagttgt
    37861 ttctctgctc cttgtggata tttcacttga aggccaacaa cttcgatttc gctatagtct
    37921 ttagctacat tttgaattgc ttctatagca tctggtttat tcgtttcaat tcctataaat
    37981 ccttttttga catctaatac cttcattaat gctcttaaac caaacacaac atcttctgga
    38041 ttttcaacca ttaatctgtg gtctgcagtt aagtatggtt cacattctgc accatttaat
    38101 ataactactt ctgccttgct atctggtgga ggagatactt ttacatggtt agggaatgta
    38161 gctccaccca tacctactat tcctgcctct tttatgatac ctactatatc ttctttgctc
    38221 aaatcctcta actgaccttt tggttgaaca ctctcatgta attcttcctt aaagtcattt
    38281 tcgataacta cacattgagc tgaacctcct ggtacttcat gttgttcaat agcaataact
    38341 ttacctgata ctgaagaatg aacgttacat gaaacaaaac cttgttgttc acctattttt
    38401 tgcccaaact ttacttcatc accaacttca acaataggtt tagctggtgc ccctatatgt
    38461 tgctgaagag gaatgtaaac tatctttgga gcttgagctt tttcaagtgc ctttgtgtta
    38521 gagtactctt ttctatatgg aggatgtatc cctcccttaa aagttaagag tttcattgtt
    38581 ttaccccctt atctataaaa aaacattttt tctgccttct ataagtatac tatatatatt
    38641 aaaaaatctt aacaattgtt aaaaaaatat ccgtattttt ataatttatt ttataaatca
    38701 acacctctat attaagtcaa attgaggaaa aggattgctt aattaaacaa tccttttcat
    38761 atagctttct aaagtccaaa ttttctgtat tttattttat agaatttata aacatagagt
    38821 actcctgcat ggatgataaa agcagacttt tacttacact atatttttct tcatttgctg
    38881 cttttgaagc tgtatcaatt ttttcattca cattctttac atactctatt aaattatctt
    38941 taaataaacg catttcagaa taatcaatct tttcagcttc ttttgatata ttttgtgata
    39001 ttgcctttct atttgtcaaa atagtattat atttttccat atctacatta ttttcagcat
    39061 tcgaccaaaa acttgattct tctttaaagt ttgttattaa tttatttaat tctttagata
    39121 tactctctat ataagcgtag ttacttgtat actctaaaga caacataggt gcatctaagt
    39181 gtgataaaaa tgcatctgga aacacctttc ttacactgct tatctgcttt ctaacatcat
    39241 tttcatcaaa agaggaatag gtctgtattt tttttactcc atccttctcc ataactgaaa
    39301 aaggtatgtc attattaact aatgatgtct gtattttttt caaatcatca ttattatcta
    39361 ttgcagcaac ttgaatagta tacatatccc agccttctat agtagctaat ttgacttctt
    39421 ctggctcttt agtgttattt accgcttttt ctggattagt ttcttgttta tcatctgaat
    39481 tggtttgtga tttagatttt ttcccttttt ttattgaatt taattcatca gatatatctt
    39541 tataagttat atctgatgaa ttatttagaa atggtatttt agccgataca tactccaata
    39601 tcttgctatc ttttattttt gtataagaat aatagccaat tagacacaag caagcaatcg
    39661 ttataacata tttacgtaaa tcaatcttat gtctattatt attaaatcct ctgtatatcg
    39721 tttttcttct attcattagt ttgtccctcc caaaattata ttattaataa agtatatttt
    39781 taagagtcac aatttatgaa tataaataat tatttcttct aattttttaa taagaaattg
    39841 tacttactaa acaaatcttc ttgcaccaag taatacttta gaccaatatg aactagttaa
    39901 attatccact ttaaccttat taggattagt ctgagtacca ctacaatgga taaatttact
    39961 atttcctacg tatataccta catgattagt tgttccatca ccatcagtgt caaaataaac
    40021 taaatctcct ggtgcataat ttcccataga aattgcactt ccaaaattag cctgttctct
    40081 agaaactcta ggaatagaaa cgcctacaga atgtttaaaa acatactgtg taaatccaga
    40141 acagtcaaat ttatcaggtc ctgaagctcc ccattgatat ggtattccaa taagagtata
    40201 tgcaaaatct acgattgttg aaccttttgc tgtagattta tctgaatttc cagtaaatga
    40261 tggctttgag ttactattag attgagaatt ttggttagat gatgaatttg gtttttcttt
    40321 tgtatcctca ttagtctcag aaatataact ggcactcacc catccaattg ttccactcga
    40381 taactttacc ttataccaac cattactttt agcttttaat tcaacaacat ctccaccatt
    40441 taattttcct attatagaat agcttgtccc aggaccactt cttacattta aactcacagc
    40501 agatgttacc ttaccattct tgccttcaat tgattcttcg ctagatggtt ttttatcaga
    40561 attattagta ctatttgaat tactagaatt gttcgttcca acatcttctg atgttttaga
    40621 aatatattgg ctactagccc atccagtaac tccatttgat agttttattt tataccatcc
    40681 attgctttgt tctagtaact ttactacatc tccattattt gctttaccaa ctaatgaata
    40741 gttagtacct gcaccacttc ttacattcag tctagaactc acatttactt taccatttcc
    40801 actaatagtt gtcccacttg aagttggatt attttgactt gatgtacctt cagacgaacc
    40861 acttgttgat atgtattttg cacttcccca tccaacaaca gaactcgata cccttacttt
    40921 ataccatcca ttagactttt ctaaaatctc tacagttttt cccttgtata attttgctac
    40981 cttatcgcaa tcagaacttg gtccacttct tatattcaag gcacttgctg ttactgttcc
    41041 cttttcaaga gcacttgcat ttatggagct aacagatact gctactgccc caattcctaa
    41101 agctgctata gcttttttca ctactatcac tccccccaac aaatttttat agtcataaat
    41161 tcataacatt attatccatt tttagtccct acaatttaat gataacttat tttcttatta
    41221 attgtaaaga aattataaac atatccttaa aattagtgat ttttaggaag tatttcaatc
    41281 caataattat ctgggtccgc tataaaataa attcccatac tttcattttc aaaacatatg
    41341 caatctaaat ctttatgaag tttttttgcc tcatcaaact cctcaacttc taaagccaga
    41401 tgaaattcat tgtctcctaa attatatggt ctatcccaat ctctaagcca agttaattct
    41461 aatgtatgac tagtaatgcc atctcctaaa taaactaata taaaacttcc atcttctgct
    41521 tccttgcgct ttacctcttt aagccctaaa gcttttttat aaaaatctaa acttttttct
    41581 aaattagtaa cattgaaatt gttatgacaa aaattaaact tcattttgaa atcactctcc
    41641 aatttttatt ttttttatat tatatcatta ttataaattt atttaaatca tattaagtta
    41701 aaaatttgaa tgatgatgac caattaccaa atcatggtaa attatttaaa agaatatgtc
    41761 aaaaaaagaa taagctcttt caaatgcata aaaaatttat acccaagtta tacttaatca
    41821 tgcaaattgg cagaacttat tctttaaaac tctaactttt aagtttttct ttaataatat
    41881 aatttattac tttttttcta atatcttcag cattataatc atcttctact tctatatcca
    41941 aaagttttgc tattgacctc atatcttctc tagtctttga cctatagctt gatattaatt
    42001 catcttttat tttctctggt tctaaaagat attcttcatc tcctcttttg aaaacaacgt
    42061 atttttgagc atatgaactt ctattgtagt atatatatct tgatattttt cttaaaattt
    42121 gattatatga aagtcgcttg ttaatatcaa gttttaagta ctctgaaaaa gcaaatagct
    42181 ctttttttga tttaaataat gcttctttct ttatagttct tgatattgaa gttacacttt
    42241 cttgatatgc acactttttt aacattttta aatatactct attaagacca atactttgat
    42301 tgaatttttt tatattatta ttaataatct tatccaagtt accttcaaag tatttttttg
    42361 ctcctttttg tgatacataa ctctcaagtt ctttgtgggc catatcaagt atcatttttt
    42421 ttaaatcctc tttatatccc ctagattcca tgatactccc tcccttagct atttatagta
    42481 tattcaaaaa gctcaagaaa tgtgagtcat tacaaaattt ttttactttt tatgtatata
    42541 ttaatttaaa aggggagata atagtaatgt aaaatcaaac atactcaatc tcccccattt
    42601 ttagacctct attactcccc caatagaggt ctttttttag tttatcaatt tctattcaat
    42661 tccctttagt tcaaatccta attctgctat cacttctttt aatttttcaa tagatacatc
    42721 atctttcata tctacagatg cacacttatt ttctaaatct acatctaaaa cttcaatacc
    42781 atctatatct tctgttaatg cagttttaag atggtttaca caatgaccac aactcatacc
    42841 ttctactaat agtttcttct tcatttaatt acctccttat accctataag ggtattctat
    42901 catatagttt atacttttta aatagaaatt aatcatttaa tttgattcat tcgattttat
    42961 atctaaatta gatattccct catatacatc aaaatcattt ggagtaattt taccttttaa
    43021 tctactatta cttacaatat agttgtttct cacagctaaa cttataaatg ttgcattatc
    43081 ttttatatat gtctgtacat ctttgtatgc tttttttgtt tcaatttcag acgtagaact
    43141 tgtaagtgca gacatatatc catttaactt atcatcagta tatccactac tcgctataat
    43201 actacttgca tctggtataa ttgatagttt ccatccaact aatgctaaat cataattttt
    43261 agaattaaga gcattttcca tatccttatc tgacagctga tttactgtac tatttattcc
    43321 tatagctttt aagttttcat ttattatgtt tgcagttttt attctctcac tattatctct
    43381 gtttactatt atctttaagt tcatttcaga aagacttttc tttacttcct ctttttctct
    43441 attttttttc tcttcagctt cttttttgat tctatcttct tctgcttttt tagcttttgc
    43501 ttcttcttct ggcgtaagct tctttgagtt ctttttagct gattttttct gattttttac
    43561 tttattgtca ttttgattta ctgagtttac atttgcatat tctaccttag caagacactc
    43621 tatcgcctta tctttattaa actctaaatc cttcatttca ctattatagt attttgattt
    43681 tgaattaagt ggaaaattaa ctggagtagc atcatccata taaccttcac taataattct
    43741 atctttatct atagagtgtg caattgcttt tctaaaatta acatctttga aaaaaggatt
    43801 attataatta aataatacac actcataatc tcttccttga tattttgtta tattaaactc
    43861 tttttcttga aacttactta aatcatttaa tgtaacattg gttatatcac tatcaagagc
    43921 cataaccata gatgtccttg catcttcatt aggcaccata cctactttta tgttcttcat
    43981 ggtttttgga acttcttcat agtaatcttt gtttacagat aaaaccattc cttctctttc
    44041 tgtatatgat tctattttat atttcccatt tcctatcata ttattattct tgtcatttac
    44101 atcttttgaa tctaaatgat tttgagatac aattggaaaa attaaactat caattgaaaa
    44161 agcatatcta gctttaaatt ttattgtaaa atctttatct gatttaatat tcacagaagc
    44221 tatattttta gtaaattcat tatatggact atctgcactt ttttgaatta aaccaatagt
    44281 atagtttaca tcatttgaag taatattttt tccatcatgc cactttgcat cttttagctt
    44341 tatatctata ctcattccat cctgagctat attatactcc ttaactaatt gaggaattac
    44401 attgtagttc tcatctatag taaataaact atcataaact aaattcatta tataaccaac
    44461 agacttatca gtattagtta taggatttat agtttttgga gttaccattg ttaagtttat
    44521 atacttagca tctatagaac tttgactttg taaacttgaa tcactactac tttgttttgt
    44581 tttagtatta ctacaaccag ctaccataag agttatagct aaaacgactg ttaagacttt
    44641 tattctcttc attagttttt tcctttcttg ccatatatct tattataatg ttcgtaatta
    44701 ttttttactt tttctacata ttttgaagtt tgcttaaaag gtatatcatg tagattttcg
    44761 ccatctttac tatattcatt attttctaac cattttttca cattacctga accaccatta
    44821 tatgcagcta tcactaaatc taatttacca aattctttgt ataacttact taaataccaa
    44881 cagccaagtc ttatattagt ctctgggtcg aaaatatcca cattttttaa atttagttcc
    44941 tctgctcccc aatctctagt tatgtctaat atttgcatta atccttttgc ttcctttttt
    45001 gaaacagcag aactattaaa cttactttcg gctttaataa cactgtaaac tatattttca
    45061 tctaaattaa attctttcga atacttttct acatactctg aatatttttt aggatataaa
    45121 aatttatgta ttactttgct ttccattaat agtgccccaa ataagattat aaaaatagat
    45181 agaatcaata ctttcttact attcacgcca attctccttc atgtactcaa taaatttatg
    45241 tgctttactt tctaattcag ttattgttcc cgaattatct attatataat caccatattt
    45301 ggatttttct tcctgactca tctgtgaatt tatcctacta agtgcttcct gctcactgca
    45361 attatctctc ttttgtattc tactaatttg tacttcttgt ttacaagtaa ctactaatag
    45421 cttgtcaacc atatctaaaa aaccactttc taccaatatt gccgcatcta acactactat
    45481 attttcgcct ttttttctca atttttctat ttcacttatt attttttctc ttattcgtgg
    45541 atgagtcaag ttatttaatt ccttaagttt ttcttcatca ctaaaaacta ttttcccaag
    45601 agcttttcta tttagagttc catcatcatt ttttatactt tgcccaaaat ggacaaatac
    45661 tttttccaat aacaacttat cctcaaatat cttcctggat ataatatcag catccactat
    45721 aggaatgtta agatttctaa atatatttga taggctgctt tttccacagc ctattcctcc
    45781 tgtaagtcct aatatcaaca taaaatcacc tactttgtct cataccaaga actacctaca
    45841 tttaaatcta catctaagtg aacatccata tttacagcat tttccatttc ttcttttact
    45901 attttcttaa ctatatctat ttcatcatca attgcttcaa ctatcaactc gtcgtgaact
    45961 tgtagtataa gttttgattt caaattgttc tcttccaatt ttttatgaac atttatcata
    46021 gcaattttta ttatatctgc tgcacttcct tgtattggtg cattcattgc aaatctcttt
    46081 cctctatttc tttccataaa attgcttgac tttatttctg gtatatatct tcttctgttt
    46141 aaaattgtta cagcatatcc atcctcacta gccttttcta ctgttgtgtc cataaactct
    46201 tttattttat ggtatttagc aaaataactt tcgatatatt ctttcgcctt tggaacaggt
    46261 atatttaaat catcagctag accaaagtca cttttaccat atataatacc aaagtttaca
    46321 gctttagctg cacctctcaa ttcactagta acatcttcca taggaacatt aaaaacttgt
    46381 gaagctgttt tggtatgaat atcttcatga tgtttaaatg cttctatcat attttcatcc
    46441 tgactcatat gtgcaagaac tcttagctct acttgtgagt aatcggcatc aaccaactta
    46501 cagttatcat ctgcaataaa cacttttctt atttttctac ccatttccat ttttataggt
    46561 atattttgaa gatttggttc tgtagatgaa attcttcctg tagtcgttat agtttgatta
    46621 aatgatgaat gtattctatt actttctgga tttattatat ttaaaagtcc ttcaacgtaa
    46681 gtagaattta actttactat ttgtctatac tcagttatct tatctattat tggatgctta
    46741 tctcttaatt tttctaaaac atctgcatta gttgaatatc cagttttagt ttttttaatt
    46801 attggaagct ctaatttttc aaataatata acacccaatt gttttggtga atttatattg
    46861 aatggctctc ctgataattc ataaatttcc ttttctaatg tagctattat ttctttaaat
    46921 tcaacactca attcatccaa tatacttttg tctactttta taccttcata ctccatatga
    46981 cctaagactt ctactaaagg catctctaca tgataaaaaa gaccatccat actcatatcc
    47041 attagacttc tttccatcat aggaactgtt tctttaactg tgcatattat ttgacccata
    47101 tactctgcta aatcctcaaa ttctaaatcc tcatagtttt tagatttaac accctttcct
    47161 aataattctt cttttgattt aacctttttt gataaatact tcatagctat tgcactacaa
    47221 tcatatgagg tagatgaagt tgaatctatt aagtactcag ctattgttat atcaaaatac
    47281 atattttcta agtttatatt atatggtttt aaagatatat aatcatcttt taaattatat
    47341 ccatactttt taatttcatt atttgaaaat atactatcta actttgacac ttcatttgaa
    47401 tctacataat atattttttc tccatctaca cttataaaaa tatatattat atttttttca
    47461 agtatattac cttgtcctct aacagttttt aaaataactt gtcctttttt gtttacttca
    47521 tctataaatt tttctatatc ttttaatttt aatatttcta ttttttcttc tacgtgttct
    47581 gtgtcatctg aatcgaccaa atcaactaat cttgataaga gacttgtaaa tccaaagtat
    47641 ctaaatttat ctaaaagttc atctttatca taatcgccaa aaatcatact atctaaatcc
    47701 acttctattg gcacatctct tataattgtt gcaagtcttt tactttgaat agctatttct
    47761 ttgttttcct ctattttctt ttttacacta cctttaagct tatctgtatt ctctattaga
    47821 ttctctatac tagaaaactc ttttataagc tttatacctg ttttttcacc tattccaggt
    47881 actccaggta tattatcaga cttgtctccc ataagaccct ttaaatcgat aaattgtgtt
    47941 ggagtcatct catatttttc aattacagaa ttaaagttgt attcttctac ttctccaacc
    48001 ccttttttcg ttataagggt agttgtatta tctgaagcaa gttgaatagc atctttatct
    48061 ccagttacta tgtatacctt atatccattt tcttctgctt ttttagaaac agtacctata
    48121 atatcatctg cctcataacc atctatttct agtctattta ttctaaattt atctaaaagg
    48181 tcttttaatg gctgtaattg ttctgccaat tcatctggca taccctttct tccagcctta
    48241 taatctttat attctaaatg cctaaatgta ggtgcttttc tgtcaaaagc tacacttata
    48301 tgtgttggtt tatatatatc tatcatttta aatagcattg tagtaaaccc atatatagca
    48361 ttggtcttta acccttcttt attattcatt tctggaagag cataaaaagc tctatttatt
    48421 attgaatttc catctattat aattaatttt ttttccaaat tatatcactc ctaaaaatta
    48481 tctatttttg taacatatat attatatacc aatatagtgt tatttaatat tcccataata
    48541 ataatagtat attaaaatta aatatgttgc aaacaatata tttttttgct ataataatat
    48601 acatgacatg cccgagtggt ggaattggta gacgcagtgg actcaaaatc caccggacta
    48661 atactccgtg ccggttcgag tccggcctcg ggcaccatta aaaactccta aagctattta
    48721 ttcaatagat taggagtttt tttatttttg atttaaattt taagttattt tttgaaatta
    48781 ctgtgtcttt ttaaaattta tataattata taaatttatc ttctagcatt aatttaaaaa
    48841 ctaatttact tttatataat tttctatttt atatcataac ttattacaac cttttatcta
    48901 atttattgta tacaacaaca ctacaaataa attgaaataa aataagcaat ccaagaacaa
    48961 ctaaaaccca cttgcttatt accattacag aaaatacact caatatagaa acaataaata
    49021 taagaattac aagaacatag cacatgattt gattagtaat acgtccagct ttatcacgta
    49081 acataattct tctttcatca ttcatctcta tcctttgatt ttttatcttt tcttcataat
    49141 ctactgctct ttcaggttta ctccaataca tatattgaag aatcatacat acacctggac
    49201 ctaaagcagc tccagataat ccccaaataa aagcctcaaa tgaaaactca gtaaatgtag
    49261 ccaataaaac aagtaaaatt ccacaaataa aatatataat tccaacatat aacatattct
    49321 ttttcatttt tactcctcct cataaataaa tatttcttca atactcatat caaagtatct
    49381 agctatctta aaggctaaga tgatagaagg attataccta ccattttcta atgaacctat
    49441 agtttgtctt gatacttgca aaatagaagc aagttcttct tgttttatgc ctctttcttt
    49501 tcttatttct tctaatctat ttttcacatc tatccccctt taatatctca actacggaaa
    49561 gtctactttc cataattata caactatatt ccatttatgt aaagcttact ttccatattt
    49621 acaaaaaaat aacagactat tttcagcctg taattttaga atttcatgtt gtttattaat
    49681 tttaatgtta tttattaatt ccatattatt tattaatttt aacttggttt ctgaattgga
    49741 atccaaactt ctgtagtata atcaggagca ttgatatcgc cattgggata aagttcaata
    49801 tctggtaaat tagcatacac atacccagaa cttggtaacc actcagtaat aattcttttt
    49861 tgcaattcct gtattgccag agcatttggc attggagaaa cacattcaaa tactgcccat
    49921 gtgcctgatg gtattaagta ttcatgagta tcttctaata caggcttatc tgttggagca
    49981 gcaatataat aatctaaacc cttactattt gtacacacac taactccaag caatccacaa
    50041 ggttcattat ttattaactc tgaaagttta tcaattgttc cattttttat gcatttagcc
    50101 cacaacttag gaactttctc aaagcactct tctacaatca tgttcatact ttcttttata
    50161 ccaacaatac gaaacccttt cttttctaca atacgatatt gcatttctat atttcctttt
    50221 acataaatgc ttaatgtcat cttaggatat gcttttaaaa caacaccctt tgctctagct
    50281 gcagatggag aaatgttatg tatattttga aaagctctat taaaagatgt tggtgaatcg
    50341 taaccatact tctcagatag ttctaaaatt ttgatgttac tgttctgaag ttcaaatgca
    50401 gccttagtca tacgtcttcg tctaatatat tcagataatg gtacttctgc aatatatgaa
    50461 aacattcttt gaaaatgaaa ggttgaacaa catgcaattt ttgctgcttc tgcataatcc
    50521 actccacttt cgagattttc ttcaatataa gtaatagctt gatttaattt atttatccat
    50581 tccatttgat attacctcca agcaaattat acagtttaat aaaataatat acctctctat
    50641 tcatgcacaa aattgtaagc atttaaattt ataagcattt ttcaatcaat acaataaata
    50701 taaaaattgt attatacaat aaaaaagttc aataacatta tattgtaaaa tgttattgaa
    50761 ctttttataa aaattaattt aagtgtagtt aaattaagta ttacactatc ttatatatta
    50821 caatatccta ctatcttata gtcttctggc actttataat ctttgtctgg agtacctaaa
    50881 ttccatttta aatcaaacat agttgcactt attattgttg caaaataaag cataactata
    50941 ccaatgtcta ttttttcttc atataaatta gtatgaccat cttttctaac agctaaaact
    51001 acagtgcctc catcaactat aaatctccat ggttgtctat ttaatgtaga tggagctaat
    51061 cttgcatagt gaaatgcatc aagaagtgct ctttcttcta agatttctat acttgcaaca
    51121 tttccccatt cgttcatata aacaacatct tctacaccta gtctagtaga ccccttatct
    51181 gttacaactt gcatatcaga ttttgaataa ttttgcccag tttttgtagc atttaatact
    51241 ttagcattac ttacattttc tccatatcca atagctataa ttcctgttac ctctttatct
    51301 gaattaattc caagtttttc ttttaccttt tttccatctt caaaagtaac ccaacaagaa
    51361 ccaattccaa gttctgttac tttaaagatt atactttctc ctatgtaccc tgaattttca
    51421 atgtaattat cttttatgtc agataatatt ataatataac ttggagaatc tatcatattt
    51481 cctttgtacc ctgctacttt atctaaatta ttaaaaactt cacttctatt cataattctt
    51541 acatcaacat ctatttctgg aactagtttc ttacaagatt ctgagtattt cttaatttca
    51601 ctaagatatt cttctttaat atctgtgttc ttatattctc taacagactt tctatttaat
    51661 atgattgttt tataatccat aattttatcc tccccaaact agtattgtct taattatata
    51721 cccattaata tattatttta ctcatttatt taataaataa agattacaat tttgtaatta
    51781 ttatttatta ataatattcc acttttacat taataatgac cagttgtgca aaatccattg
    51841 ccaaccacca aataaaaaca tattataaag gtaatataaa ataacaaaca aatcttaaca
    51901 aaaaattaaa ctttttttac acgaaagaag gcttcccgtt gccttcttta tttttataaa
    51961 aaaataagct gtttctaaaa tgatttcaca tttttgaaac agccaagtta ttctataatg
    52021 acaactataa tttgaggatg tgagggagag ttgtcattat aaatttaggg taattatatt
    52081 atgttttaag ctagttcttt ctatatttat ataatacatt ttatatatga attttatatg
    52141 agattggtat aaatgatata tgaaattaca tatgtttata ttatattaaa ttttattatt
    52201 acattttcca caacaatact catatgtctc cacattattt ggaatattta caaatacaaa
    52261 ttctttacag ttctcacaat actttaatat agatatagtt ccacaagtgt aacattcaaa
    52321 tattacacaa tcctcatttt cctctactat ttcaaacttt ttactatgtt caccacactc
    52381 tgggcacttg tgattattta cattcataaa tactcctcct tattagtata gttacatgtc
    52441 aaaaacttaa ttaatgtatt ctatattact tattatatat tctataataa atcatattct
    52501 aatataataa aacaaattaa ataaaaaaaa aaccataaat tttaaattta tggattaatt
    52561 cttgtaatga taactctatt tgaggatgtg agggagggtt atcattacaa tagggtatta
    52621 tattatggtt tttaagctag tctttctaca cctcatatga tacatatgct atatgaattt
    52681 tatatgattt ttacataaat attttatgaa atttaaattt tttagtcatt ttgaaatttg
    52741 taaaaagttc tctaaaaatc cacagcatca taaacagcca aaatttaagt aaaacatcat
    52801 aaaaaaattt gtccaataat tttaacaagt aatctcacct cattataatt attgacacaa
    52861 acttaaataa acaatctata aatcttctat aaatcttaaa ctttccccct attgatacac
    52921 aatttctagt ttgtcaattt tattttgcat ttctaagaaa atttcttcaa cagaattgtt
    52981 aaatatattg cctaaataga ttcttttatc tttttgaaat gaataagatt ttacactacc
    53041 atcagaagaa atatataaat gactccactc tgctccatat tttgaaaacc tctcctttgt
    53101 atctttaaac ctcatatctt ctatttttat tgctttttct ctgtctcctc ttactacagt
    53161 gtgacccctt tttattaaac tggttatttt tatatcttct tttaatttaa tacgtgtatc
    53221 atcatttttt gaatatactt tccatatcac tttatgacga taattatcta attcctttat
    53281 taagcttcta tcaatagtaa aactatcttt agttaccaca attaaatcaa aatggtctaa
    53341 catatattga aatatttctc tcatactttt attttttaaa atatcctcac caataacctc
    53401 tataaatcta cagcctttct catacatgca gttcaataaa cttgtgattt cagaaaaata
    53461 atcatttgta ttattatctc catctatttc tatagtaaag tacaaaggag taatgtatga
    53521 tttatttcct gttatctcaa atacacttga tagtgtctgt atatcatctt caaacgttaa
    53581 gtacacattc tcataaaaca taaaaaattc cataactttt tctttcatat tatggatatt
    53641 tctatatcta ttggataata tatttattat atcgtcagta gtatttttcc catcacattc
    53701 agccagtata acaatttgct tccaacttaa gctatccaca tttccgatac tttttttata
    53761 tccatcttct tcgtcataaa taggaccaat tataatgttt tcttttggcc acagatgaac
    53821 cctagttcca tcttttaatt tcggatattt attttttaca gactcataaa atctacttgt
    53881 atcacccatg attctttact accccccata gtttaaatat tctatgctaa aaatagcact
    53941 ttatttttat taattcaaca attattcaaa attggtcatt atatatgttt aaatggattt
    54001 aacatcaacc ttatttatat gttattgatg tttatatatg ttatataaaa tcttatttct
    54061 catacttaaa tgtaatctta actatctctg gtttacaatt aagcctaatt aaaacttttg
    54121 agcctcctaa gcctttattt aaaatcatag tgctattatc tttttcatat tttccccagt
    54181 catacttagg aaagaactct ctatttggag ataatacacc tccaacaaaa ggtattctta
    54241 ttatacctcc atgaacatgt cctgctaaaa ccaaatctgc tccccatttt gcatattttt
    54301 caaagaaaaa tggtgtatgt gctaaaagaa tgttatattc attttcatta actttaccta
    54361 gattgtcttc tacaaaattg tcacttagtt ctaatttttt gttattagca aataaatatg
    54421 gatagcattc caatggtata attaaaccat ataaattaag atggctatta cctctatata
    54481 ttcttacaga ttcattttcc atatttatta ttttctttga atatagttcc ttaaaataat
    54541 ccttatatag atgtttatac ttttttatta aagatttttg ttcatgattt ccaattatat
    54601 gatatacttc atatttttca accaaattat ctattaaatc taatgcaact tgaaaatttt
    54661 tattttctcc atctactaaa tctcctgtta taaatataac atctgggttt aatgattcaa
    54721 ttttatctat caatacctta ttatttttat caaacacctt attatgtaaa tcactcactt
    54781 gaactatttt aaagttatca aattcctttg gaattttttt gttgaaaata gtatattctg
    54841 tcgtttctat atgctgagtt tcatacttat acagaatata caataatatt aatactaata
    54901 ctgtcattga aacctttata atcatattct cttcctcttt attctatttt gttaatatta
    54961 ttataatgct tttatgtttt ttttaaaaca ataacatcat cacatacata taaatctttt
    55021 cgacattata aaaataagtt atccttttct aaaattttca tttattttag aaaaggataa
    55081 ctataaaatt atctataaac ctctatattg tgaaatatag tttttccttt atttaaattt
    55141 ttatatatat gctctaaagt tccatcaaac ctaatagaat gtccagactc taaaatataa
    55201 gttttcccat ccacattaag gtcaagttta ccttctatta cgagcacata ttcttctaaa
    55261 acatgactat gtgtagatga aacatgagta cagttttcct caagctcaat tataaaaagt
    55321 tcaaaccttc tttgagggct aaaagggtat attggatata acttcatgtt ccctttttgc
    55381 tcaacaatag gctctacttc ttctttcttt ataacctcat aggtatttgt attttcattt
    55441 aatagtgtag taaaatttat tttaaatcca gatgaaattt tccataaagt agatactgtc
    55501 ggacttgatt cacctctctc aatctgtcca agcattgctt tactgacacc tgtcatcttt
    55561 gaagctttgt ctaaacttat gcccatttct tgtctcaata accttaaatt ttctcccaca
    55621 ttaggaaatt tattatccat gttaaaatcc tcctgatagc tatttgtatt ctatgatttt
    55681 tactcctgta agttctacta tctcttttaa ttttaacata tgattgttac aaatatcatc
    55741 aaattcatat atataatctt caagccctaa tgccttatat ttatcgattc caaatttatg
    55801 atatggaagt aactccatct tgcctcctgg aacattttgt ttgacaaata atgcagtatt
    55861 tcttatattt tcttcactat catttactcc ataaataatt ggcactctta taaccataga
    55921 tttattcaac tttgaaagcc tacatatatt atctaatata attttattac ttactcctgt
    55981 atattcttta tgaatattat catccataga ttttatatct acaaatatgt ggtctatttt
    56041 ctcaaataca tcatttacct tattccaatc aaaatatcca caagtttcaa ttgcaatatt
    56101 tatgccttta tcataaaaaa tatcaactaa ttctcttaaa aaatcaatct gaagtgtagg
    56161 ttcacctcca gaaaaagtta tccctccatt agattcaaag aaaaatataa aatctttttc
    56221 aacttcctct actatttctt caacactcat ttcttcggtc attatacaaa tggcatcttt
    56281 aagacatacc ttgatacact ctccacataa atcacattta ttatttattt gcgctctatc
    56341 aaatagtgaa cttatatttt gaggacaaac atctatacat ctattacagg atacacattt
    56401 atctttcata acacctaatt ttactatgtt actccaggaa tctggattag aacaccactt
    56461 acattttaat ttacatcctt ctaaaaatat agtagtcctt attccatctc catcatttac
    56521 tgaaaaatgt tgtactttta caactctacc ttttttactc ataatctacc tcataattaa
    56581 aaattgctat gtgaatttct agctattata gcatcttgca tttctcttga taaattaaca
    56641 aattgagtac tatatccagc aaccctcact aataaatctt tatattcttc tggattttct
    56701 tgagctttta atagagtatc atttgatatc gtattaaatt gtacatggaa tcctcctaaa
    56761 gcaaaatatg atttaatcat agatgttaga tttctaagtc ctctttcagt ttccaccaaa
    56821 tcttgattca gtcttaaatt tagaagtgtt ccaccagtat gaacatcatg atttattttt
    56881 gatgcagatt tcattgctgc tagtggactt gttgtatcag taccaacaaa tggagaaact
    56941 ccctctgtca aaggttttgt cgcttttctt ccacaaggag ttgcacctac tatttttcca
    57001 gttggtacat agtttgatat acccataaat gcactattaa atttagagcc aaaaatatcc
    57061 ttgtattttc tagtttcagt ataataaaaa tcagaaactt caattgctaa tgaatctaca
    57121 taatcattat catttccata cttaggaaca tccaacgcaa gttttcttaa ttcttcataa
    57181 ccttcccaat cattatttag tgcttttgtt aattcttcta acgtagtcac cttatcctca
    57241 aatactaatt tttttatagc tgccaatgaa tttgaaacta cacctaaccc tataccagtt
    57301 aatacaggac ctatattata ttttgctcct cctttactta aatcaactcc cttatccaaa
    57361 catccatcta cacaagtaga taaaaatggt cttggtacca tttctttatg aatttgttga
    57421 gcaacagtag ttcctataac agaacttttt acaagatatg ctaattgctt taaaaactca
    57481 tccttaagtt cttcaaaaga agtaaattct gtgatatttt ttgtatctaa ccccattttt
    57541 tctccagtta atctactctt accttcattc atagcatatt ctaaagctgc tgcaaaattg
    57601 atatttacgg ctgaagtcca ctgtcctgtt tttctaaaat gaggaactac acaaccacag
    57661 ttactccaat ctctagcatc ttctgcatca tatccatctt gtaataacat ttgtgcccct
    57721 gcactatcgc tgtgtatagc agggaaacca gttccttgtt ttaccaattt agcaactgcc
    57781 attacgaaat tatctggtgc tccttgactc actctaacac ttaatcctgg ttggtgagtt
    57841 tttacacttt ctgtagcctt taaacacata tatgagatat cattcgttcc atcagtacca
    57901 tttctctttt taccaccaac agtaagattt tggaattgat tatatcctgc aaagtaattt
    57961 gctgtatttg ctgatatagt ccatacccat tctgataact taatccaaag tgcttctatc
    58021 aattcttgag cttctgattc agttatttta ccttctctag catcattttc ataatatgga
    58081 tacatatatt ggtcaaatct acctaaattt aatgccaatg gattttctga tagaatacca
    58141 cctaattgaa caaaccatac aaattgtatt gcttcataaa aattagttgg agggtttgct
    58201 ggtacattca tacatatctc tgaaattttt ataagttcta actttctctt ttcatctgtt
    58261 tcttgcttac tcatctcttt tgcaagattt gaatatcttt gtgccaatgt cataataccc
    58321 tgtgcaacta tagaaacaga tttgtaaaaa tctatctttt caatattttc tgaaactgat
    58381 atatctaatt ctttaatttt tttatctgca tcttccttaa tccctttata tccttttaca
    58441 aacaatatat cttgataatc tggtgttact tcaccaactg cctgtctcca cttagaatca
    58501 ttatctatta ttcctgtatc tactaatatc ttagctgtat cttctgggat tcttgctaag
    58561 aaaacttctt ccaaagattt tcccttccaa tatggaaata tttcttttct tataaattct
    58621 atttgttctt ttgatattac atatgggtct tgagttcttt tatcaaaagt atccatttct
    58681 ttgtctaccc attgccaaga aaactctggt gtcaatatcc ctgttcttct aaattttcct
    58741 gctgtaccta ctattaattc attttcaaag atttttatag gaagttcttt acatgtctcc
    58801 aaaaaagctt tagctcttct tatacagata gcttctccct cagttttttt atgtgattct
    58861 gtaaaaattc tagccctttc acaacatatc ataggtttag aattaatata ttcttgtcta
    58921 aatgcttcta ttctattagt ttgactcatt taaaatcccc ctttggataa tatatactac
    58981 atttttgtat gttataacat actttaatta tattatactg tcctttagca taaaatggaa
    59041 gcaaaataac ttattttttt tcatctacct tgaacaccta tatattaata ctttttttgt
    59101 taaatttata aactctaaaa aaattttcta tgatatattt tctatattgt tatagttatt
    59161 tctaatatac taatgatttg aaatatcaaa tttgtatact agacttagtt ttaaaacctt
    59221 agttgattgt ttaactttgt taacttcaac atgtatatcc ttcatataag gaagctctac
    59281 aacacctact cccttattaa agtcttcttc aaccatagaa aaaatttctt tctcagttaa
    59341 gttcgtatta gtcaatgact taaataaatt gtatataaat ttaatatatt tatcactctc
    59401 agataactta tcatcttctg gatactcttt agcacagaga atatctattg ttacttttcc
    59461 ttctttatcg tcttcagaca tagaatagaa taaacttcga atattttttt caggtggttt
    59521 ttcagcacca tttatagata ctacaaagct accatctgat tttgagtcag taatactata
    59581 accactgtct attatagctt tcgaaaatct ttgagataaa tcttttttta cttcttctct
    59641 acctttcgca tcattaatct tttgtgagta attattaaaa agctcgatag attcatcttt
    59701 tttatcttca acttgttctt tcaacgaatc tttactaatt tgttctgagc tacttaagtt
    59761 cttatcatat acaggagaca tacaccctac catcaatgct aagctaagat ttaaagccac
    59821 aatgattgcc actctattta tattcctttt tactttcata cacaatcctc ccatcacact
    59881 aaccgctcta aagtattact tattgcacta gaatatgttt atattttctt tatattaaag
    59941 atttattatt caatacatat caccttccta tccaattctt ataacttact attagtaaaa
    60001 ttataagctc cttaatacag aaataaggat gttatctttt gttattaaaa gataacatcc
    60061 ttattttttt gtatcaatac atatgtccca actggtaact taatcgcccc aactgtcagt
    60121 atcttggtcc aatggtatat atatatttag tataaattta tcgatactat tttcaaataa
    60181 taattctcca ttatattttt gtaaagaaga tttaatactc tgaataccta ttccatgtac
    60241 aaacttatcc attttgtttg ttaacaatat atttttatta aaagtaagct gatttagttt
    60301 actattttca catttaagta caaaaaatga ccttgtcata gttcctttaa ttctaatata
    60361 tttattaaca ttttcatcca ctattttatc acatgcttct attgcattat ccaaaatatt
    60421 agaaaatatg cttgacacat ctataggttt tacaaaattt acttttgaaa aatttataga
    60481 gcaagtaaat ttaattcctt tttttaaaca tatttcactc ttttcgttga ttataatgtc
    60541 taatatcata tttcctgtat tatagatata tttaaatgtt tttatttcat cttttaaatt
    60601 gttaacatat tcattaattt ctttgctatt gtttctaagg ttgtctatac aataaatgtg
    60661 attatttata tcgtgatata gtttcttaac tcgcatatga gattcttgaa tacttaaata
    60721 atgcgcatat tgcatatcta acttattttt tattaattca gcttgagatt ttaatctatt
    60781 ctcttttatt atttctttaa acaatagtat aagaaatata ctactagctc ctaccaattt
    60841 tggattaaca aaattatcaa aatagtatcc ttctgaatgt aatgacccaa accgttctaa
    60901 tttttttaat acataattta caagcatatt cattgtatta actaataagg caaataataa
    60961 atatacataa tttctcttat cttggctaat taattttata gacttcctaa aaaagctaaa
    61021 tataagatat ataagaataa ttattaaatt actatatatc tgaattttta tagattctaa
    61081 gtgaggtact aataaggatt ctttagatga aataacatta cctgtaattg caaaaaatag
    61141 tattctatat ataacagcat ccaaacattt ataatataca ctaaatagat aaaagaaaat
    61201 ggaatactta atataaccca tcttataaaa ataattatag tatcctcccc aagcaataaa
    61261 tgctaatata taaaataaat agtttatatt actaaagtaa tttcctccat taaataatct
    61321 acttatctga attataatat aaataagaaa caagacaata tagaatacta ttttttcatt
    61381 ttttttacta tcctttttat aaattaaaat tccgttcatt atagaaaact gtataaatat
    61441 agataaaact actaatagct cagtcataaa gtttagcata ttgtatcacc aagaaatttt
    61501 aagaatttct ccttaacttc tttatatcta tatctactaa taggtacctc ttctccactt
    61561 tccagtattg cagtattagg ctttatattt tcaacatatc ttaaatttac tataaaactt
    61621 ttatggcatc ttataaattt atatggattt aattcttttt ctattttgcc taaactatat
    61681 tttatatcaa aattcttgtt tattgtgtgt attagcatat cttttttttg aacttctata
    61741 tattttattt catttaaata aatcttatat gtattagact tattttttat tgtaatatga
    61801 ctttccttat ttatttcaat atctttgata caagttagca catgtttttt tagttcttcc
    61861 aactctattg gctttagtaa atacctataa gctcttacct cataaccttc ttgcacataa
    61921 tctattaatg aagttacaaa tattatttcc atttcattgt ctacttctct aatctttctt
    61981 gcagtatcca ttccatttaa tttttccatt tttatatcaa gaagtaatat atctatatct
    62041 tttaaattac tttccagtaa ctcttctcca gatatatact tttgtatctc atattctata
    62101 cttatatctt ttaatatatt ctcaaggtaa tcttctatta aaagttgtgt ttctttttca
    62161 tcttcacaaa ctgctatctt aatcataaaa tgcctcctta cataatttct agttaataca
    62221 attaaaatat ttataatata tttaaagata attttgtata tctgatactt taggataaca
    62281 ttttcaaatt atttttatca atactcaatc ccatataact attatttgat atttcaattt
    62341 aaagacagaa attactataa ttaaaaacag tacttactga taaaagaaga tgtcttaaac
    62401 tattaaaaaa ataattttag gacaccttct tttatttatt taaacttttt aagccttaaa
    62461 taatacatta atctcctata taattgtact gcatataaaa tcaacaatat aatctgtagt
    62521 acaatagcag ttacagatgc tccataacca ctatataaat ttcttatttc aatattcaat
    62581 aaatatataa atattactac taacataaag aatataaaca tattcataaa taaaattgac
    62641 tttactttgt tttttttatc agaatcacta tataatttag gaggtatgtc tttgtattct
    62701 ttcgaccata tataccatgc agatgtaccc ataaaactac caatactcct aaatacaaga
    62761 ttccagccat ttgatttatg ttcatcaaaa taattattct ctacatcata gtagtaatca
    62821 acagtgtatt ttatttttct tggacttccc ttatgaaaat aaaatattcc tccaaattta
    62881 tttatcttat ataaattata tcctttagct tcaatatctt ctaaccattt ctctatctta
    62941 tcaggtgaac tataccagtc aaatttgaat tttattttct tttccatagc actcattctc
    63001 caaaatgata tttttaaata gcttaaaaat ctatttaaat aattatatca ttttgatact
    63061 aattttaggt tacaatcata tatttaaaaa gctatttaaa tagtaataaa ctaatagcca
    63121 taacacccat tcctgcaatc aatccataaa tagataaatg atgttccccg tactctctag
    63181 ctgatggcaa taattcatct agtgatatga ataccataat tcctcctaca attgcaaata
    63241 caattccaag agttatatca tttaaaaaat ttctaagaag tacatatcca ataatcgctc
    63301 ctaaaggctc agacatacca gataaaaagg aataataaaa agctttcttt ttatctcctg
    63361 tggcataata aactggtaca gatacagata taccttctgg tatattgtgt attgcaattg
    63421 caattgctat cggaatagct attgtaacat catcaagagc tgatataaat gtagctaatc
    63481 cttcaggaaa attgtgaatt gctatagcca ttgctgtaaa tatacctgtt ctcaaaagag
    63541 acttattttt tttgatattc ttttcttcta tattctccat tttctttatt tcatgtggat
    63601 tttcttcttg tggaattagc ttatcaataa cagcaatgat agccatacct ataaaaaaag
    63661 ctattacagt tgaccaactt cctaatttct ctcccataga ttttgtcaaa gcatcttgtg
    63721 ctttaggaaa aatttctatc atagaaacat aaatcataac accagcagaa aatcctaagc
    63781 ttatagaaag aaacttagta tttgtttttt tagcaaaaaa tgctatacaa cttcctatac
    63841 cagtagataa accagccaat aatgttatca aaaatgcaaa tattacatta ttcaaataaa
    63901 tcaccttctt tttaattgat attgattatc attttcttta tgctatcata tatattttat
    63961 atagtcaata tttataaaaa atatacacaa taaaaaagca gagatataaa cttagtctct
    64021 gctttttctt tatagtatat taaaattatt tatttaagaa atccactgca tattgcacat
    64081 ataaagcagt tccaatttct agagcatctt catctatatt aaagcatcca tgatgatgag
    64141 gataacaagc accttttgac tcatttctag ctcctacaaa tgctagtgca ccaggtgcta
    64201 tattcataaa ctcagctaaa tcttctgctc ctgttacttt ttcaaatagt gttatacagt
    64261 cttctccaaa tagcttaatt gctgcatctg tagctatctt tgaacattct ttgtcattta
    64321 taactgctgg tgttaagtac ccatactcta attcagcatc tgctctatat gcttctgctg
    64381 tagattttgc tatacgttct aaaattccag gaatttgctt tctaagctct ggattaaata
    64441 gccttattgt accttctaag acagcttcac tcgcaattac gttaaatcta gttccagaat
    64501 ttaaaactcc aacactcaca actaatggtt ccagaggact tacttctcta ctaaccatag
    64561 attgtagatt cataactatt gctgaacttg caagcactgc atcaacacct tgatgaggaa
    64621 gtgaaccatg accacctcta ccttttacag taattttaaa gaaatcagca gaagccattc
    64681 ttggtccttc ttctaccgat atggtcccag attctacatc agtccaaaga tgtattccaa
    64741 acacactatc tacaccttcc atagcaccat cttgaatcat agctcttgca cctttaccaa
    64801 cttcttctcc tggctgaaaa aataatttta cagttccatt gatactatcc ttaatatcat
    64861 ttaacacttt tgctgcccct agaagcattg atgtgtgacc atcatgacca caagcatgca
    64921 taagtccttc atttttagat ttgtattcta catcagtgca ttcaacaact tgtagagcat
    64981 ccatatcacc cctaagtgct acagtctttc ctggattagc tccttttata gttgcaatta
    65041 cacctgtacc tccagctgat acatatggta tccctatttt atcaagttct tctttaactc
    65101 tctttgatgt tctcacttct tccatacttt tctcaggatt ttcatgaaat tcccttctaa
    65161 gcttaattac atagtcttta taactctttg ttatttcttt aatatccatt ccatacctcc
    65221 aagtagtaca cattcttctt atttaaaata ctttttatca cttaaatact atattagatt
    65281 tacaaagata cctgctatta ctacagaagc tattgtaact gtagtaaatc ctccaacaag
    65341 catctttgga agcatcttat ccattaaaaa ttctttttct tctggtgttt cagccaaagc
    65401 ctttactgcc tcttcagtta atatatagtt tggtggaaaa ccataaagtg atgtaagcga
    65461 aactgaaaaa gccatttctt tactttcacc taaaagctta cctactataa tagagaatat
    65521 tcccatacct attacaccaa atattatgat tcctacaaga ggaactgcca tttcaacaag
    65581 cattgctggt gtagcttttg ctaaccctgc aaatataaaa gccatcaatg atgtcattaa
    65641 ccatccaaat gaaccagatt tattaagtgg ttttctatca actattccaa gttctgatgc
    65701 tattacacca aatattaaac atataacata tcttgataca acttcatttg taagatttgt
    65761 aaattgtact gctaaccatg ctacaaatcc taatctaagt attatcatat atgtcgtatc
    65821 atatttttct ggtaagtctg gtattatctt aaatctgctt ttttgttcag gtaaatcctt
    65881 aactttttct tcatctgtat ttacagttac ttttccactt ctaaagtctg ataaaagtct
    65941 ttttccttct tttttaagca ttaatgctgt aataggataa cccgcaaatc cttgtgcaac
    66001 atacatcaaa attgcaagta ctgataaact tgcaagacct tttgctgtag cagcatctgc
    66061 catcattata gatgcaacta gccctccagt aagaggaggt gtagctatta ctgctgtatc
    66121 ccatccaaat actactgtcc ctaatgccaa agcacctaca catattccta ctattcctgc
    66181 caaggctatt actattgttt tccattgacc tgctaattcc ttaatactca tcatagttcc
    66241 catatgagtt attaacaaaa gcatacctaa ttgagctaat ggtgttccta aagcggctaa
    66301 gtccacaata ttttctggga aaaaagtcca aaatcctact ataaatataa ttgctgatac
    66361 aaaaaccgac ggaacaaaag ctttagtttt tgctgaaact atatctccta tcgtcagtga
    66421 tactaaaact agacaaaaag ctgttattgc ctccatacaa aatcccccct cataataaat
    66481 atatttttat aaaatgtatg tatagttatc cattatttta ctacttttga aaaacatttc
    66541 aagtcaaaat tcgatttttt tcataaaatt cgataaattc cataaattaa agttagtttt
    66601 ctaaattatt ctttttgtaa aaacgttatc ccgaccattg gctatttaac tctattctta
    66661 caaagagaat taaatgtaat ttgcaaaaaa taaaacatag gatacatttt attcataaaa
    66721 catcttataa atataaaatg aattgtcttt atgaatctta atatatccta tgtttgtaag
    66781 tttaatgtgt atgttagcta tggtgtaaaa tttgtatact agttattgtg taacctacta
    66841 tatactccat ttttgtttac tagctcttca tgagtacctc tttcttcaat tcctttatcc
    66901 gtcaatacta tgatttcatc agcatttttt atagtagtca atctatgtgc aacaactaaa
    66961 tttgttctat ctttacttaa ttcctctaaa gactcttgaa tttctctttc tgttacattg
    67021 tctaaagcag atgtagcctc atccaatatt attattggag gattctttaa aaagattctt
    67081 gaaattgaaa ttctttgttt ttgcccacct gataatttta cgcctctttc tcctatataa
    67141 gtatcatatc catctggcaa agtctctaca aagtcatgta ttctagcttt tttagcagca
    67201 gctatcattt cttcatctgt ggcattaggg ttcccacaaa gaatattatc tcttatagtt
    67261 cctgtaaata aaaatacatc ttgttgaact atacctatat tttttctcaa tgattttaaa
    67321 ctaacatctt ttatactctt tccatcaatt tttatatcac ccttatcaaa ttcataaaat
    67381 cttggcaata aattacataa tgtagtcttt cctcctccag aaggtccaac taatgctata
    67441 gtcttaccag cttttataga taaacttaaa ttatccaaaa cttgagtctt atcttcatat
    67501 gtgaaagata tattttctat ctcaatgtca ccttttacat tttcaagttc aataggattt
    67561 ttagcttctt tttgatggtc ttgttccatt atctctatga atcttttaaa acctgtcata
    67621 ccattttgat attgctctgt aaagtttatt aattttttca taggttgtat aaacattttt
    67681 acatatagta tataagcagc aaaatcaccc aaagtaatct ttcctatata agtaaaataa
    67741 ccaccagcta ttacaactac ccactctaag atatccatgt ataaattcat accagagtaa
    67801 tattctgcca ttaccttata agaatcttgt cttgctcttc taaataattt attgcttctt
    67861 acaaacttat ttaactcttc tttctcagta caaaaagact tagttacctt catacctgct
    67921 atactatttt ctaaagtagc atttacatca cctatagtaa ctctactctt cataaaagca
    67981 atattcatct tatctttttt agctattgca aaccaaatta taaacggtaa tatagcaaat
    68041 attataagcg taagaggaat atttatatct ataagtataa agaatgaacc aaccaacatt
    68101 actatagaaa tgaataaatc ttcaggccca tgatgtgcaa gttctgttat atccattaaa
    68161 tcatttacta ttctagacat agttactcca gatttgttat tatcaaaata cgtatttgga
    68221 agtctttgta agtgtgtaaa tacctcattt ctcatatcag cttgcatatc tacaccaata
    68281 acatgtcccc aatactgcat aaaatagtta agccctgctt ttgctataaa tataagtata
    68341 agtgctactg caaaaactac taacattctt aagtttttat ttggaacaac gtcatccatt
    68401 atatttctag ttatcatagg ataaactaaa tcacataagg aaaatagaaa agctgctata
    68461 aggtctagtg taaaaatttt cttatatggc ttataatatt tgacaaattg ttttatcata
    68521 agtattaaat ccctccttta ttagtacttc tattagtact tctaaaaaat acccataaat
    68581 tagtataaca taacaataac tttaaatctt ttataaactt acaaagtaat aacaatcttt
    68641 ttcataaaat tgaagattta tatcatatag ttgtatactt gaaacaacat aaaaagagct
    68701 atatctctat atttaaaatt ttataaagat acaactctat atttaatact aaattttttt
    68761 tataaataca aaactacttc aatgcattta atatcttttt atctaatgct gttgtattta
    68821 tacctgttat atatcctgtt gcctttattg taggtatatc ataagttgtt ggtagtatag
    68881 tagtagatac gattaaatca gcaccttctt gttttgttga acattcagca attttacatt
    68941 gctcaacttc tgcttgtata ttattttctt taaccaatct ttctactctg tcacaaacta
    69001 ttgttgatgt tgcgattcct gctccacagg ctactaatat ttttttcata tattgtcctc
    69061 ctacaatttc tttaatattt tataactcaa aataaaattg ataaatttct tatatcttta
    69121 tttatataaa taattatatc attttatata agaagaacat cttaaaatta ttcttttaat
    69181 atgtttttta tttcaacatt gcttatactt aaaatttcat tttttataca agactctatg
    69241 tactttgata tatttttata atcatttaaa ttaaactgtt caatattcaa tttatattct
    69301 atatcactaa caatacctat caaatcagac ttattagata aaatatcctc atacttacct
    69361 tttctagtta cttccagtct tttaaatcta taatttttat atccttctat gataatcaag
    69421 tccatatctt catataattg aatcatttta tataatggat tcttctcttt tagttcttca
    69481 atatatgcta ctcgtttatc tgatattata cagacttttc tcgccccaga ttttctatgt
    69541 ttataagtat cttttccttc ctcatccata tcaaaatcat gacaggtatg tttaataact
    69601 ccaacacgat accctttttt atttaattct tttattatgc cttcaatcaa cgtagtttta
    69661 cctactcctg aatatgagac aactgacaat atattataca taaaattgtg tcctttcata
    69721 aaactatcta ataacaacat ccactaattg attttctttt attgtctcat tctttttaat
    69781 cttaatcata caattacttc ttagagttgc agatagtcta gcttttgcat ctttcttatc
    69841 atttagctct acatacaatt taccttcact tgtatatagt tttccactta caaatctatc
    69901 tttatttgaa aatttattaa attctccttt aaatatagct tttatatgat gtgttccctt
    69961 cttatatgtt aaatactcaa taacaggaac tatcacatta tcaaatacca ctattgctgc
    70021 atgtggatta ccagaaagac caaataatag cttttctccc aatgtaccta cataacaagc
    70081 tccaccaggt ttaatgttta tcttccaaaa taattctgtt gcccctattt ttttgaatac
    70141 atctggaatt aaatctttat ctccaacaga aacaccacct gtggtaatta aaaaatctac
    70201 actctgtaac atattcttta cctttttttc taactccaat atatcatcag aacaattgca
    70261 tattgtatct gcttgtattc caagttttaa taatcttgaa tataaggtat atctattact
    70321 atcgtatatt ttaccattct ctaaagtctc atttatatct tgtagttctg tacctgtatt
    70381 caaaattcca acttttaaat catcataaac agttactttg gatattccaa gacttgctaa
    70441 tactccaata ccatcatatc ctatattctg atttttatta ataatcaatt gccccttttt
    70501 tatatcctca cccttaaata tgtaattatc gtattccttt aattttatat ttaaagttat
    70561 catatcacct ataactgtta catcttcttt ttttattaca caatttgcac cctgtggtat
    70621 ctttccacca gtcattatct tcactgcttc atttttattt aataccctat taaatacatc
    70681 tcctgcatac aaagtcccta taacctttaa atttctattt tcagaatttg cattatatgc
    70741 ataaccatca tagggtgacc tatcaaatgg aggactatca attgttgaat atatatcttc
    70801 tgcaactacc ttatttactg catctataag atttactatc ttgaccctgt ttattggtaa
    70861 aacatttttt tcaataattt ttatggcatc ttctaattct atcattttaa atactcccca
    70921 atatattttt tatttaagat atttctatgt aatatattat agattataaa agttggaaat
    70981 acttttatct tatatttaat tataactaat agttatctat aagtgcagtt caaattttat
    71041 aaatctaata aaaaaactgt tcccagctag aaatttcctt ctatcttgaa acagcatcat
    71101 atgctttaga atattttatt ctaataaagt tccttttatt atttttacaa ttttatcact
    71161 ttcaatagtt tttatagatt ttattttgtt atccacaata cttattgtaa gtacctcttt
    71221 ttttaatatt ttgttatctt ctttcaatct ataactctta actactttac tgccttcatg
    71281 attatatgct gttaaatcat aattcgcatc tcctacaatt tcatttattc tggaatcttc
    71341 aacaccaaca tactctccca ggtcaatatg tctaaaattt tctagtgata cagccgattt
    71401 ttcatggtca cttttttcaa tcactatact agattcagca tcaatgactg atataccttg
    71461 tgatgagaaa gaattggttt caacattgac aactttattt tcgttaatat caacatataa
    71521 agcacttcca tctagttcat catttccagt atattttgga taaactaatg tcatataact
    71581 tgatgtattt atatcttgca ttgtatttga ttcttttaaa actttaggtt ttatataata
    71641 aaatgtatta taaggtatac ccatattctt tataatgtac ttataatctt tattcataat
    71701 ttcattaaca tcattttgaa cttttgtcat agttttttgc tgtgttgctt tacttgctac
    71761 ttgatttttc tctttagtat tttctttatg acatccaaca agtataatac ctaaaatagt
    71821 tacacaaact aatgaccttt ttaacttcat aaatcaatcc tcctttctta aattttatag
    71881 tatttatcta tatctcaatt tacagttatc tcttttttca ataattatat ttattatatt
    71941 ataaaataat tatataatat ttatttgaat ttaataagat taagaagcta attgtaattt
    72001 ttctgtaata aaaaacactt taaagttgaa ttttgaaaat tcaatttacg atatttttat
    72061 tgtaagtacc ttacaacatt ataccaaatt attcctaaac aatcaaaaac tccatgaata
    72121 tttaaaggtt ttctatttta aaaatcacct ttgactatta atttatcaaa tatgttataa
    72181 tagttttaga taatttaagg aggattaaat aatggatttt aaacaacttg aagtatttgt
    72241 tgctgttgca aaacatcaga gtttttcaaa ggctgcaaga gaactttttt taactcaacc
    72301 tactgtaagc gcacacatac agaatttaga gagagagcta gaaactgttc ttataaatag
    72361 aagcaacaaa gttattacac tcacaaaatc tggtgaaatt ctttatgaac atgctatata
    72421 tatattgaat aattgcaaac gtgcaattta tgatataaaa gaatattcag gaaaaataga
    72481 aggtattata gatatagcat gtagttccat acctgaaact tatattttac ctgattttat
    72541 gaagagtttt tctatgagtt atccagatgt aaaattttcc ataagccatt atgattctca
    72601 atatgctata tcagaaattt taaatgaacg aataagcttt ggattagttg gttctaaaat
    72661 caataatcct caaatagagt acctagactt attagatgat gaacttgttc ttatcactcc
    72721 ttcagatttt aaaattgata ataaaaataa ttgtatcgat ataggagaat tggcttatct
    72781 aaattttatt atgagaaaag aagggtcagg tacaagaaac ttaatactaa acacacttag
    72841 taaaaataac tttccagtaa gtaaattaaa tgtaatcgct catgtagaat caaatgaggc
    72901 tattaaggaa atggttagat taggtcttgg agtgtccttt atatcgtaca tttcagctat
    72961 cgattatctc aatgcaggta aaataaaatg ttataaaata aaggatgttg attttactag
    73021 aaagtttttc ttcatttact ctaaaaagaa aactttttcc ccattagaag ataaatttct
    73081 aaacagatta tgtgagtatt tcgaaattat aatataataa ctttaataaa gtagtgctta
    73141 attttgagtt tataactaat taataagcta attataacta tcacataaat gcttataaat
    73201 tattatgaac catctttctt ttttatttaa tttagtcaaa aaatccctcg ttcaaatgaa
    73261 cttgggattt ttttatttat actactccaa tagcagccaa tactatacaa ataatcataa
    73321 ctgaaattaa tatcgtagtt gtctttacct tttttcctaa taaccaatac ataataccga
    73381 atatcatagc tggaagcata catggcatta tttggtctaa gtaagtttga ataggctctg
    73441 cccattctcc actacctaca ttaacactaa gttttaacat tacattagat gcagtcatac
    73501 ctccaattac cataagccct aacattgaag ctgcttccat aacttttgaa actatacttg
    73561 aaccactcac atctttaaag aattgagttc catacttaaa tcctttatct agacatatat
    73621 agcgtataat aaaatgagga acatttatta ttaaaaggaa taaaatcggt cccattatgt
    73681 taccctgaga agctaaagct ataccaaccc cagctgctat aagctttaat gttccccaga
    73741 aaaatgaatc tcctatccca gaaactggac ccattaaact tgatttaaca gcatttatac
    73801 tattagcatc aaattcttta ttctttgcat tttcttcttc catagctcca gatataccta
    73861 ccaaaagagt acttatatga ggagtaactg acataaattc taaatgtctt tttaaagcct
    73921 tagatttctt ttctttatca tctttatata atctacggat tattggtgcc atcatgtatg
    73981 catatgctat attttgcata cgttcgtagt tccaagatga atctaatgtc aatgaccttc
    74041 taaaacattt ccaaaagtct ttcctcgtta ttttactatc tggtgaaatt gtctctaact
    74101 tcttagaact cgttgtcatc tactattacc tccttctctc ctacaaagtt aacatatatt
    74161 aaagctattg ctaatccaaa caatgcaact cctgttactg ttatgtttag gtaagcaacc
    74221 aatataaatc ctaataataa aaatgctact gttttcttat taagcatcat tctagctaac
    74281 atggcaaaac ctattgctgg aatcacgcct gctgcaacat ccattccatg agttacatat
    74341 gatggtataa atgaaagtat tttttctatt actggaacac ctaatgaaaa tcctatacct
    74401 actattattg ctaatattaa tttatttcct ataccaaata ataattgcac acgttctacg
    74461 ccttcaatat tcccctcttc tgcataacgg tcagcaatat gagctcccca tgtaagtact
    74521 actgtcatta agaagttatc tataagcaat actagagttg ctataggaac tgcaagtaca
    74581 actgctgctg atacatcttg acccgttaat attacaaacg ctgtggcaat aatagaacca
    74641 gacacaaaat caggaggatt acttgcccca acaggaaatg cacccataaa tactaattct
    74701 aatgttgaac ctattactat acctgtatga agattaccta gtgctaaacc aacaagtggt
    74761 gcaacaacta taggtctatt atgcattgta gaacctacaa aactatgcat atatgcaaag
    74821 aatgcaatta gagttatcaa aataacttgt gtaaattcca ttttcatccc cctaaaatta
    74881 tattaatttc attacatttg tagcatcatc atcaggaact aattgtacaa atacatttac
    74941 gccttctgaa tctaactctt taatcatctt tatatcatct tttgatacat gcactgcttt
    75001 agatatattt tcacgattat catctgattt tgttccacca aggtttatag atttaatagc
    75061 ttttacctct ttagcaagtc tataaacatc ttctacagat tcacaaagta tcaataagtt
    75121 gtatttatca gtaacacctg agttaagtgc ttttatagaa tctgctatgc ttttcattac
    75181 taacttaaca ttagatggtt tagccatttt aagtcctgcc attctcaatt catcttttaa
    75241 taagtcatca cttgctatca atatacagtc tgtgcttaaa aactttgtcc atgtaaatgc
    75301 tacttgtcca tgtataagtc tgtggtctac tcttactaat ttaatcatta taattcctcc
    75361 ctaatttttt tgatttcatc catgaatgtt tttacgtgtt ctacactaac atccccaaaa
    75421 tctttgtaat tatctttaaa gtaacttcct attattgcca tatctcctaa tttaagctgt
    75481 ttttttgcat tttctaatgt aactccagca gctataacca atgggaagtc tcctaaattt
    75541 ttacgaaaca gttctatttt ttccattgat gtttcttgac ctgtagcatt ttctgtaact
    75601 gctatagcat cacatcttgt cattcctatt tttaaatctt cttcaacatc attttctgat
    75661 aatactggct gatatttaaa acgtacgcct ccaattaaat acgctgggca ttttgaacgt
    75721 tgtaatttaa aaaactcttc taaagtagct tcatctctag gtttaacatg acctactaca
    75781 gaatcaacct gtatataact agcattatat tttgttgcca gttcaaatcc catagtatca
    75841 acatttaaac agtttactcc atatggtatt gataaattag cttttgatac atattcaagt
    75901 attctttcta aatcataata attaccatag taattttcta acattattcc atctacacca
    75961 ttttcttcaa agattgtaat ctctttttta gctctttcaa agatatcttc tggagtatct
    76021 ccttttaagt gtatcattgc tataattggt tttttacttt taaatactga taatattccc
    76081 ttttttttca taaactaaaa tacctcttct tcttctttaa tttgtaatgt cacgctttgt
    76141 attcctcttc tagattcttc cactaattgg tctatatctt caacggttaa ttcatcagaa
    76201 aaccttgtaa gaagttctaa taccatattc aaattcattc cagaaaataa cctaacatta
    76261 tgtagattag ttaatcttaa cattgctgta catacacttg ctccatataa gtcagataaa
    76321 attatatatt cacattcttt atcttctgat attgtttttt ctaattctaa agcaaaatct
    76381 gaagcacttt gtccagggta caaaccatac gaactgacac aatctgctaa atctcctact
    76441 atcattttta ctgcatttaa aagccctttt gaaaagtctc catgagatgc taatattatc
    76501 tttttcatac tcatcctcct actaaattat agattatatt tctgctgata ctgcatattt
    76561 gtacttatca cttcttataa attgctcatt gtaatataag acatcattat tttctgtata
    76621 caccgattgt cttactttca atagtggcat attacttgca catttaagat ggtcagaata
    76681 ttctttgttt gaatgtttta cttcaaatat attttctact cgtttaggta atgtgcttat
    76741 attattagat ataacctcca ttaaagattt atcttctaat tcttctttta ataaaaacat
    76801 gtaatctatt ctaaaatagt caacttcaaa aataacaggt acttcatcta ttaatctaag
    76861 tcttttaata catattacct tctcttctag ttcaatactt aaagcttcag ctacttgctt
    76921 atctgctttt tttattaaaa cagagattat tttggtactt ggttttgcat taatacgatg
    76981 acaagaatta gtaaaactat ttcctgcaca tgttgcttct attctctctg gtattgttac
    77041 ataagtccct ttaccacgtt ttttacataa tatatcttct tttacaagtt cattaagtgc
    77101 atttctcaca gaaattctta tattttattt atgtttattt atatttattt atgtttttat
    77161 gagtacattt atttacaacc tatctaaaac aatttcttta ttctatttta tttatatttc
    77221 tttatttgta ttttatttta ttaaactgtc atggtggcaa aaaaggtggc aaaaataatt
    77281 tgccacctaa aataatcttt atttattctt tctcttttaa atttttaaaa tgttcttcga
    77341 gttcgattaa tttatcttca tccacttcat catctttact atgtaacgct gatattaaac
    77401 ttgaaattga attcttgtgt atgttcttca aaaattcctt tgtttcaaat cttagatatt
    77461 ttttctcttt taccattgca ttatagtgtg taagtttacc tattttctct gtacttaaaa
    77521 actcccttcg ctctaacctt tttaaaactg tgaatgtagt tgattcattc cattcgtatt
    77581 tttcttccat tgcggcaact aattccttag aagttaatac atcgttagct tcccaaatat
    77641 atctcataac ttttaattct gcttctggta atttactaat tttcatagtc acaccccttt
    77701 atcgaattat gtatatgtta aattctatct caataaagtt ttccaaacaa gagaatcaca
    77761 ctaaatatta ccatccaatt ttttccatct cgaaattatt cttctaaatt tctataatat
    77821 tcttctaatg cgtctagttt ttctttactt atagacttat gtgtagtagt aagagaacgc
    77881 attatttttc tgcttttgct agattttaac acttttttct taaaagcata atattctttg
    77941 ttatctatta ttattttata atgagattga aactttataa tatctctggc caaataacct
    78001 ttgtcaacta gcctttttag tagtattttt attgtacttt tatgccatcc ataaacctgt
    78061 ctcatttctt ttacaatttc ttttttagtc actagagaat cttttttcca taaatactcc
    78121 attactatta attctgctct taataatttt tctactaata tttcttcttt caacttatgt
    78181 cactccttcg attgttctag ttcaagttaa taataagagc tttttaagac aaaaactata
    78241 ggtaattttt accaaatatt ctactgtttt agtttgtttt cttagaagaa aaataacttt
    78301 cat
//
LOCUS       DAMJVG010000006        77412 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.006, whole genome shotgun sequence.
ACCESSION   DAMJVG010000006 DAMJVG010000000
VERSION     DAMJVG010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 77412)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 77412)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..77412
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.006"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(121..894)
                     /locus_tag="PC512_000479"
     CDS             complement(121..894)
                     /locus_tag="PC512_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SigB/SigF/SigG family RNA polymerase sigma
                     factor"
                     /protein_id="HDF2440256.1"
                     /translation="MKNVANATHYLNMDTKELFNLYNKNKNVDIRNILIERHLYLARL
                     LAKKYINKGVDFEDIYQVASLALIYAIDRYDVEKGFEFSSFATPTIVGEIKKYFRDKV
                     WTLRVPRRIQELSKKISDAKIKLEQENKKHPKVKDIADYIGVSEEDVLEAMEASYGYQ
                     PMSLDSSSNDDSEDKDITLIDKIGKEEGNFGSIEYEDFINKFIETLNELEVKIFKDRF
                     FFDKTQSSIAKELGISQMTVSRLEKKVVEKLKKEYEKNL"
     gene            complement(894..1280)
                     /locus_tag="PC512_000480"
     CDS             complement(894..1280)
                     /locus_tag="PC512_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2440257.1"
                     /translation="MEITTNPDYVSIIRLTASGIANKMGFPIDDIEDIKVAVSEACTN
                     AIKHSKDDVFNIVFNILDNAINIEIQDNGKGYDVSSISTPDLENPKESGLGLFIIKTL
                     MDDVDIESEHNQGTKIKMTKYLGVDI"
     gene            complement(1305..1622)
                     /locus_tag="PC512_000481"
     CDS             complement(1305..1622)
                     /locus_tag="PC512_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="STAS domain-containing protein"
                     /protein_id="HDF2440258.1"
                     /translation="MSMNIDSNLDSQNKFWNVCLDGELDVSTADKLKEHLHALIEKNM
                     LDVKINLKDLDYIDSTGLGAMIGVLKKLKINEKEIYIVNPKSNVRKIFTITGLDKIFK
                     VEG"
     gene            complement(1634..1894)
                     /locus_tag="PC512_000482"
     CDS             complement(1634..1894)
                     /locus_tag="PC512_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HDF2440259.1"
                     /translation="MNAWGWQIGAVLVGSSALIVAIYLAKTLNSINKVVEKAYKIVDY
                     NERHIQDIVENASSISKGIDDIVYVINKILSIGNIFKIIKRK"
     gene            complement(1894..2190)
                     /locus_tag="PC512_000483"
     CDS             complement(1894..2190)
                     /locus_tag="PC512_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HDF2440260.1"
                     /translation="MCNKRSCKKGGFLLLGAILGFIFGMFFAPKKGSELRKETKEKFN
                     DVKENPKEVLHETFNDVKERIINLVDDDNNEEDIKISEEDIVISKSFDDEGDVN"
     gene            complement(2259..4685)
                     /gene="gyrA"
                     /locus_tag="PC512_000484"
     CDS             complement(2259..4685)
                     /gene="gyrA"
                     /locus_tag="PC512_000484"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HDF2440261.1"
                     /translation="MEENNKILPIEIAEEMKKSYIDYSMSVIAGRALPDVRDGLKPVH
                     RRILYSMSELNLTPDKPYRKSARIVGDVLGKYHPHGDTAVYYAMVRMAQDFSTRALLV
                     DGHGNFGSVDGDSPAAMRYTEAKMSKLSLELLRDIEKETVDFKPNFDESLKEPSVLPA
                     RYPNLLVNGSNGIAVGMATSIPPHNLAEVIDATVYLIDNPECSVDDLIKFVQGPDFPT
                     AAIIMGKESIAEAYRTGRGKVKVRSRAFIEELPKGKQQIIVTEIPYQVNKAKLVERIA
                     ELVKEKRIEGISDLRDESNRNGMRIVIELKRDANANIVLNNLYKHSQMEDTFSIIMLA
                     LVDGQPRVLNLKQILYHYIKHQEDVVTRRTKFELNKAEARAHILEGLKIALDNIDAVI
                     SLIRASKTGQEAKLGLIEKFKLTEIQAQAILDMRLQRLTGLERDKIEAEYEDLIKKIN
                     RLKEILADERLLLNVIKDEITIIKENYSDERRTEIRHAEGEIDMRDLISDEEIAITLT
                     HFGYIKRLPSDTYKSQKRGGRGISALTTREEDFVRHLVTTTTHSRLLFFTNKGRVFKL
                     NAYEIPEGKRQAKGTAIVNLLQLSADEKIATLIPIDGNDENEYLLLATKKGIVKKTKR
                     EEFKNINKSGLIAIGLRDDDELIGVELTDGKQEVLLVTKEGMSIRFDENDIRYMGRTA
                     MGVKGITLSKEDFVVSMNLCSKGTDVLVVSKNGFGKRTNIEEYRSQIRAGKGIKTYNI
                     SEKTGTIVGADMVNEDDEIMIINSDGVLIRIRVNEISLFGRVTSGVKLMKTNDEVNVV
                     SIAKINIEEE"
     gene            complement(4705..6606)
                     /gene="gyrB"
                     /locus_tag="PC512_000485"
     CDS             complement(4705..6606)
                     /gene="gyrB"
                     /locus_tag="PC512_000485"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003226808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HDF2440262.1"
                     /translation="MKQEYGASQIQVLEGLEAVRKRPGMYIGSTSPRGLHHLVYEVVD
                     NSIDEALQGYCSDIYVSINEDGSVLVKDNGRGIPVEIHPKTGKSTLETVLTNLHAGGK
                     FGGGGYKVSGGLHGVGVSVVNALSKWMVAEVYLNGKRYKQTYEKGLPTSKLEVVGESQ
                     DKGTMIQFMPDETIFDEIEFKYETLEYRLRELSFLNKGIKIVFEDKREGQEKRKEFHY
                     TGGLVEYIKYLNKSRTGIHDDIVYIDKKVDDCFVELAMQYTDGYTENIYSFANNINTH
                     EGGSHLSGFKAALTKTVNDYAKRNKFLKENDVNLLGEDIREGLTAVVSVKLPEPQFEG
                     QTKTKLGNSFMRGIVDSVTVDELGSFLEENPSTARIIVDKALRAQRAREAAKKARELT
                     RRKSVLESTSLPGKLADCAEKDPSKSEIFLVEGDSAGGSAKQGRDRNSQAILPLRGKI
                     LNVEKSRLDRILSSDEIKNMITAYGCGIGEDFDIDKARYHKIIIMTDADVDGAHIRTL
                     LLTFFFRYMRPLIDEGYVYAAQPPLYKVTKQKKEHYVYSDKELNILLDEIGRNGVELQ
                     RYKGLGEMNAEQLWETTMNPETRTLLQVTVEDAAIADEVFSMLMGDKVAPRKEFIEEN
                     ARFVRNLDI"
     gene            complement(6607..7722)
                     /gene="recF"
                     /locus_tag="PC512_000486"
     CDS             complement(6607..7722)
                     /gene="recF"
                     /locus_tag="PC512_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HDF2440263.1"
                     /translation="MKLKSLQLVNFRNYKKLHLEFNGKVNLLVGKNGQGKTNIVESIY
                     MLSFGKSFRTNKDKEMVRFNSENLYIGGSFSKYNKYSLIELIIGKDKKGIRINKVPLQ
                     KIQELLGNLNVVIFSPEDLRLVKEGPKERRAFIDKEISQIIPKYYKYLTNYNKTLSQR
                     SRVLKNIHVDEALLDVYDDTLAKYGSYIYILRRDFIKKIANISENMHMNLTNGVERLS
                     IRYKNQINITDEDTIDTVYNKFLAKLSSNRPNDIESKTTRYGIHKDDLNIFINDLDAR
                     LFGSQGQQRTASISLKLSEIELIKNEVEEYPVLILDDVFSELDEARQKLLVNNLSNVQ
                     MFITSAEVSHKKIFDEKNVTIFNIENGDVISIENGGN"
     gene            complement(7739..7945)
                     /gene="yaaA"
                     /locus_tag="PC512_000487"
     CDS             complement(7739..7945)
                     /gene="yaaA"
                     /locus_tag="PC512_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HDF2440264.1"
                     /translation="MTEITIESEYIKLDQFLKLAEIASTGGHAKFLIQEGLVTVNDEI
                     ELRRGKKIKSGDIVEIEGTKIKVL"
     gene            complement(8082..9188)
                     /locus_tag="PC512_000488"
     CDS             complement(8082..9188)
                     /locus_tag="PC512_000488"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HDF2440265.1"
                     /translation="MKIICNQKILANRIGIAQKAINGKTTIELLKGILISTEEGQLKL
                     TGYDAEIGIETYVQAEIIEKGDVVVDARLFGDIIRKLPDSFVEIETDSENNIYINCVN
                     SRFKIKGYAAKEFPKLPELNEEDLYSIPQEILKNMIKQTVFAISQDQTKPVLMGELLE
                     IVDRNLNLVAIDGYRLAVKSCSVDSLTENIKVIIPGKTLIDVNSLLSGEDNVKVGFNE
                     KNAIFIINDTKIITRLLEGDFIDYKKLLPREHNSRVKLNTKELLNSIERASLLSQSEK
                     NNLIKLSIRDKVMAITSNTEKGNVYEEVEIDLDGDYLDIAFNSRYFIEGLKNIDNEEI
                     FIEFTTNVNPCIIKPTDDVNYIYLLLPVRISSNI"
     gene            complement(9430..10752)
                     /gene="dnaA"
                     /locus_tag="PC512_000489"
     CDS             complement(9430..10752)
                     /gene="dnaA"
                     /locus_tag="PC512_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HDF2440266.1"
                     /translation="MMDIVSLWDKTLQLIKGDLTSVSFNTFFKNIVPLKIHLNDLILL
                     APSDFNKDILENRYLHLIEDAISQLSLKKYNIKFVLSEKEVADLNSDSTDLNYRVLYP
                     NLNPKYTFDTFVIGNSNRFAHAACVAVAESPAKAYNPLFLYGGVGLGKTHLMHAIGHH
                     IVSQKKDSKVVYVSSEKFTNELINSIKDDKNEEFRNKYRNVDVLLIDDIQFIAGKERT
                     QEEFFHTFNTLHEANKQIIISSDRPPKDIPTLEDRLRSRFEMGLITDIQAPDFETRIA
                     ILRKKAQLERIDVPNEVMSYIAKNIKSNIRELEGALTRVVAYSSLSNRVISFDLATEA
                     LKDIITTSKNEEINVLRIKEKVSSVFNLKMEDFNSKKRTRSIAYPRQIAMYLTRELTD
                     LSLPKIGEEFGGRDHTTVIHAHDKVSKDIEESEEIKTKIDKIISDLKG"
     gene            11408..11545
                     /gene="rpmH"
                     /locus_tag="PC512_000490"
     CDS             11408..11545
                     /gene="rpmH"
                     /locus_tag="PC512_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HDF2440267.1"
                     /translation="MSKRTYQPKKRQRSKEHGFRKRMKTSNGRNVLKRRRAKGRNRLT
                     H"
     gene            11623..11967
                     /gene="rnpA"
                     /locus_tag="PC512_000491"
     CDS             11623..11967
                     /gene="rnpA"
                     /locus_tag="PC512_000491"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HDF2440268.1"
                     /translation="MDFNRTKGLKKDSDFRKVYKHGKSFANKYLVIYILKNKSDYSRV
                     GISVSKKVGKAITRNRVRRLIKEAYRLNIDEKIKPGYDIVFIARVSSKDATFKDIDKS
                     IKNLVKRTDISI"
     gene            11999..12250
                     /gene="yidD"
                     /locus_tag="PC512_000492"
     CDS             11999..12250
                     /gene="yidD"
                     /locus_tag="PC512_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HDF2440269.1"
                     /translation="MNKIIYILKEISKHLSNLCIYLVRFYQKYISPLKGPTCRFYPTC
                     SQYSIEAFKKYGFVKGMYLTIRRLLKCHPFHPGGYDPLK"
     gene            12282..12989
                     /locus_tag="PC512_000493"
     CDS             12282..12989
                     /locus_tag="PC512_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HDF2440270.1"
                     /translation="MNIIGNFLGLILKVIFEFVNHYGISIILFTILVKIILLPLTIKQ
                     TKSTKAMQDIQPRIKEIQEKYKNKPEKQNEEIVKLYGEAKINPLSGCLPLLIQFPILI
                     GLFSVLREPVAHGVFANKAAFLAADNGFLWIKSLTSPDYVLAVFSGASAYVMQKVMTP
                     KDQLQGSMKVMTYVMAGMSFYWGFIFPAGLTLYWTVSNLFSIAQYYLIMNPLKAKLAA
                     NSKEEKVNEKKPKINKK"
     gene            12958..13587
                     /locus_tag="PC512_000494"
     CDS             12958..13587
                     /locus_tag="PC512_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HDF2440271.1"
                     /translation="MRKSLKLIKSKSKEEAISKAIAELNLKAEDIEVEILENPSKGFL
                     GFIGAKDGTYEIFVIEREVDVAKNFIEVMLKNANVDAKVNVSQKDNLIMVDIEGKEAA
                     SLIGRRGETLDSIQFLTGLALNKINKDSHTRVLVDIENYRSKREESLIRYANKVAREV
                     AKTRKTKKLDYMNPYERRIIHSALQNDKYVITYSEGTDPYRRLVIECKR"
     gene            13699..15078
                     /gene="mnmE"
                     /locus_tag="PC512_000495"
     CDS             13699..15078
                     /gene="mnmE"
                     /locus_tag="PC512_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HDF2440272.1"
                     /translation="MFIDDTIAAIATAPGEGGIGILRISGEKALKVAEEIFKSMSGKS
                     IEEYNKRTLIYGNIVDNENVIDEVLLAYMKGPNSYTGEDVIEINCHGGFISVKKILEL
                     ILSKDVRLAEAGEFTKRAFLNGRIDLSQAEAVIDVIKAKTDIAHEVAQNQLEGSLSKK
                     IRELRDKVTEILAHVEVAIDYPEEDIEHITYQTLKEKTDELKKDIKKLYDTAESGKIL
                     REGLKTVIVGKPNVGKSSLLNSILGENRAIVTDIPGTTRDVIEEFVNIKGIPLKIVDT
                     AGIRDTDDIVEKIGVEKSKESFTSADLIVMVLDASRKLSEEDIEILEKLKDKQTIVLL
                     NKNDLKQEIEEEKILKYVENNSIIKISALQQEGIEELQDKIESMVYKGSIKNNSSLVV
                     TNSRHKDALSKAYKSATDALIALEQSMPFDFVEVDLKNIWDYLGYINGDTVTEDLLDN
                     IFHNFCIGK"
     gene            15176..17068
                     /gene="mnmG"
                     /locus_tag="PC512_000496"
     CDS             15176..17068
                     /gene="mnmG"
                     /locus_tag="PC512_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012065747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HDF2440273.1"
                     /translation="MKFEAGKYDVIVVGAGHAGCEAALATARMGYKTLIITMSLDSIA
                     LMPCNPSIGGTGKGQLVKEIDALGGQMGLNIDKTYIQSRMLNTAKGPAVHSLRAQADK
                     FKYHEEMKKTLEDEPNLDIAMDEVVEILHEGNVVIGVGTKLGCSFKSKAVILATGVYL
                     NSKIYMGEVAFYEGPNALGYAKYLTDSLVELGLRMRRFKTGTPARVHRDSIDFSVMSL
                     QEGDEKVTPFSFMNENIEKKQEPCYLTRTTEETQKVILDNLKRSAMYSGVIESTGPRY
                     CPSIEDKVVRFSDKTSHQLFIEPEGLNTKEMYIQGISTSLPFEVQLDMYKTIKGLENC
                     KIMRPAYAIEYDCVDPTQLKISLEIKGVENLFSAGQFNGTSGYEEAAAQGLMAGINAV
                     RKIEGKEPFVLDRSEAYIGVLLDDLVTKGTNEPYRMMTSRAEYRLYLRQDNADMRLTQ
                     KGYDIGLVKKDRYERFLNKKAAVEKEFERLKNERVTPKEVNSLLEEKGATPIKVGISL
                     YEFLKRPEVTYELLEELGKGAGEDVSREVKEQCVIITKYEGYIEKQLKQIDQFKKLEN
                     KKLDEKINYSSIEGLRLEARQKLDDIKPISIGQASRISGVSPADISVLLIYLEQIRRT
                     RGGKGE"
     gene            17061..17780
                     /gene="rsmG"
                     /locus_tag="PC512_000497"
     CDS             17061..17780
                     /gene="rsmG"
                     /locus_tag="PC512_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HDF2440274.1"
                     /translation="MNNIELLKNGIEGFNIDTNDSMLEKFKIYREILVEWNKKMNLTG
                     IEDEKEVYIKHFLDSISAVKNGYIKNGMSIIDVGTGAGFPGIPLKICLDSLELTLLDS
                     LNKRINFLEEVSRVLELDNITFIHGRAEDFGKNEDYREKYDVATARAVAGLPILMEFC
                     VPFVKVGGYFICLKGPNANLELEESQKAIDVLGLEYIEKIDVELPEVDLNHNILVFKK
                     VMETPVKYPRKAGKPAKNPIK"
     gene            17943..18728
                     /gene="noc"
                     /locus_tag="PC512_000498"
     CDS             17943..18728
                     /gene="noc"
                     /locus_tag="PC512_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid occlusion protein"
                     /protein_id="HDF2440275.1"
                     /translation="MEDKRVMEIPIEDVVPNPYQPRKIFSQVSLEELSNSIKVYGIIQ
                     PITVRAKDGKYELIAGERRLRAAKLAELKTIPAIINNMNDESSAVLALLENLQREDLN
                     FIEEAIGYENLIKEHAFTQQQLAEKLGKNQSTVANKLRILKLPNDIKMKLIENNLTER
                     HARAFLKLPSEDLMQSVLDKVIKNELTVKKTEKLIQDVLEETKVQEEPDKKQNIKGAM
                     SIRIYINTIKQAFDAISNTGIDAKYNEIDKGDYMEVVVKIPKK"
     gene            18863..19636
                     /locus_tag="PC512_000499"
     CDS             18863..19636
                     /locus_tag="PC512_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HDF2440276.1"
                     /translation="MGKVIAVFNQKGGVGKTTTNVNLSASLGTLGKKILVLDLDPQGN
                     TTSGYGINKNEVENTIYEIMLDGLHIKEAIISTEFENVDVVPSATELSGAEIELTSKT
                     NREYILKNSIKAVIDEYDYIFLDCPPSLGMLTINCLTAVDSVLIPIQCEYYALEGVSQ
                     LMETIKLVKSRLNADIEIQGVVLSMFDGRANLSIQVVEEVKKYFKGSVYTTLIPRNVR
                     LAEAPSHGKPVIYYDKRCRGSVAYLELAEEFIDLEEEEW"
     gene            19638..20501
                     /locus_tag="PC512_000500"
     CDS             19638..20501
                     /locus_tag="PC512_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HDF2440277.1"
                     /translation="MENKSKRSNRLGRGLSALIPEIKGETSEKEIVNIDIDKIYPNEV
                     QPRKQFDEEKIKVLSDSIKNYGVLQPIVVKMDENNKYMIIAGERRFRASKLANKNQIP
                     AIIKDIDMKDIMEIALIENLQREDLNSIEEALAYKSLIEHYNVTQEEISEAVGKSRPH
                     ITNTLRLLNLGQDVIEMIDSGRITAGHGKALLRIADKDLQLQIAKKIEEEELSVREVE
                     NIAKKISENKQEEPKKSKPKDVFILDVEDKLRNIFGTKVNISKGKKKGKIEIEYYNDD
                     DLNSIVSMLLE"
     gene            20534..21676
                     /locus_tag="PC512_000501"
     CDS             20534..21676
                     /locus_tag="PC512_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HDF2440278.1"
                     /translation="MIYLDNAATTYPKPERVYNAVLDCMKNYCANPGRAGHKLAMRAA
                     REIYDTRENIAKLFNVSNPMNIVFTSNATDSLNLAIKGVLQEGDHVITTSMEHNSVIR
                     PIKALEKRGIENTVVKCDYEGFLDYEDLEKSIKNNTKLIVTTHASNVCGTLIDIKKVG
                     EIAKKHNILFLVDASQTAGVYDIDVNECNIDMLAMPGHKCLFGPQGTGILYVREGLNL
                     NILKEGGTGSKSEEIVQPELFPDKYESGTHNTPGIAGLNQGILFIFERGINNIRQHEE
                     ELCQYMIDKLEEVPDIKIYGPKDSKKRASVIALNIGDMDSGEVTFLLDSDYNIATRSG
                     IHCSPLAHTTLGTLKQGAVRFSIGYFNTKDEIDKAVEALKKISKNK"
     gene            complement(21810..22385)
                     /locus_tag="PC512_000502"
     CDS             complement(21810..22385)
                     /locus_tag="PC512_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GerMN domain-containing protein"
                     /protein_id="HDF2440279.1"
                     /translation="MKNKKIMLVLSILSISIFAVGCTNAQNGSDSSKKETKSNTNVEQ
                     PKEENNTEKEVPNNKAKPTPKEETKAQSATIYSFDVDKTDLIENKVDLNKIDENTLFE
                     ELQKLKVVPESAKLNSFTTKDIDGVKTGILDVSSDFTKSNLGSDAETLMLDSVARTYI
                     KNMNVEQIKITVDGSNYESGHIVLEEGDYLK"
     gene            22645..23937
                     /locus_tag="PC512_000503"
     CDS             22645..23937
                     /locus_tag="PC512_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HDF2440280.1"
                     /translation="MEILSLGEKIKKLRKEKNMTLKELAGDRITAAQISHIERDKSHT
                     SYELLEYLGDKLDVSVEYLLETKEMQSKKITDNLILQSEIYIKENELNKAEDQIKEVL
                     DICKRYDLMENYGRCNFLMANINLKKSNYNDAIENFEKALYFFIKNSDSENILKCYLN
                     IGKIYMQEDFYKGAISHFNFAEEILSESKFEDVNIHKELYSKMAYCYIKLDNPNMSLK
                     YIEKINEIDNRNDRKEDVDILVLKANNMLEIGKYEESRDYFKKALKILESEDNKTGLA
                     NVYLTICDVYRKIGETDRVLEYSQKVYDIKKNDEDEYMMSGLFKIIEAYIDKEDYDLA
                     RKYCKIALASSIKNKNKFNEYKALRFYANMYKNQNEVTLAIEYLIKCIKIVSDLGNNR
                     ILANLYIDLGQLYSNISKEKELEYYQKGVFMYKNLEIM"
     gene            24042..24644
                     /gene="yedF"
                     /locus_tag="PC512_000504"
     CDS             24042..24644
                     /gene="yedF"
                     /locus_tag="PC512_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase-like selenium metabolism
                     protein YedF"
                     /protein_id="HDF2440281.1"
                     /translation="MSIKIDARGLACPKPVINTKRELDNLEEGVVVTIVDNETAKENI
                     LKLAKSLSCEANIVDEKENFISIEIRKGKNILDKQNVVDNKESELDNTCIFISSDKMG
                     LGNDELGKVLIKGFIYTLTESKPYPKYVLLVNGGVKLSAENEETIENLKILENMGVEV
                     LSCGTCLDYYNLKDKLQVGTVTNMYTIVETLKNASNTISI"
     gene            24717..24980
                     /locus_tag="PC512_000505"
     CDS             24717..24980
                     /locus_tag="PC512_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3343 domain-containing protein"
                     /protein_id="HDF2440282.1"
                     /translation="MNQMYIVSFNSTHHAIRSEKLFGENSLKVMALPTPREITASCGI
                     SIKFSFEDMEKIKTILVENNVDIKGIYCISKLENGSKEVEKLD"
     gene            24995..25180
                     /locus_tag="PC512_000506"
     CDS             24995..25180
                     /locus_tag="PC512_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HDF2440283.1"
                     /translation="MPMDLKIGDIVELKKQHACGCKEFEIIRTGMDIKIKCTKCSRLI
                     MLDRETLEKRVKKLIKK"
     gene            25283..26479
                     /locus_tag="PC512_000507"
     CDS             25283..26479
                     /locus_tag="PC512_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDF2440284.1"
                     /translation="MAVKYAKRMQGLQGSEIRELLKLTQQPQIISFAGGMPAPELFPV
                     EEMKKVSVAVLEENGRSAMQYTTTEGYEPLREKIAARMNDKNKTNVNKDDILVTSGSQ
                     QGLDFAGKVFIDEGDVILCESPSYIGAINAFKSYQPKFIDVPTDSDGMIMEELEKILE
                     TTDRIKMIYVIPDFQNPTGRTWPLERRKKFMEIVNKFEIPVIEDNPYGDLRFEGETLP
                     SLKSMDTKGLVIFLGTFSKIFCPGYRLGWTCASPEILSKFNFAKQGADLQASTISQME
                     VSKFMDMYDLDAHVDKIKAVYVKRRDVMLKTMEEEFPEGLVFTHPEGGLFTWVELPSN
                     LNAKELMPKCLDKNVAYVAGGGFFPNGGRENTFRLNYSNMPEEKIIEGIKNIAAVLKE
                     AMGVEA"
     gene            26693..26971
                     /locus_tag="PC512_000508"
     CDS             26693..26971
                     /locus_tag="PC512_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HDF2440285.1"
                     /translation="MRNYELVYVVKPNSDEEVREAILNKVKEVVATDGEIVKVDTWGT
                     KKLAYPIAKFTEGFYVLVNFKSAVDVPKEIDRNLKINENVIRHMIVVA"
     gene            27008..27442
                     /gene="ssb"
                     /locus_tag="PC512_000509"
     CDS             27008..27442
                     /gene="ssb"
                     /locus_tag="PC512_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDF2440286.1"
                     /translation="MNQVVLVGRLTRDPELRYIPGTGTPVASFTIAIDRDYVKKDGSK
                     ETDFIPVEVMGKSAEFCANYITKGRLVALQGSIRVDNYQTQSGEKRTFTKVSTRSVQA
                     LDSKNKSENSYRESAPAFEPSFEPQGLDPQGFQAIDDDDIPF"
     gene            27461..27688
                     /locus_tag="PC512_000510"
     CDS             27461..27688
                     /locus_tag="PC512_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HDF2440287.1"
                     /translation="MMNKKRRKKKRVCQFCADKNAKIDYKSTQRLQKYITERGKILPR
                     RISGTCAKHQRELTVAIKRARNIALLPYTLD"
     gene            27831..28151
                     /locus_tag="PC512_000511"
     CDS             27831..28151
                     /locus_tag="PC512_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HDF2440288.1"
                     /translation="MKIDKGSEITRNIKIIEWMKTEILMSVSDLFNLLFKGVKPLDEA
                     IQDTLANIIMITYLLAKRLGISFRDVDYKVKEKIKIGIDEDHSVERWYGDLSNLKKHM
                     DNRE"
     gene            28159..29115
                     /locus_tag="PC512_000512"
     CDS             28159..29115
                     /locus_tag="PC512_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YybS family protein"
                     /protein_id="HDF2440289.1"
                     /translation="MNNKIRLSKAMSIIVLAIIIALVIAYIPMLGIFSMLAAVPYVII
                     GAITDRKYSLISILVTFCVLILFADISYALNICIMYSLPGIVIGKMLKRSFEQEDSNK
                     FEPIYGGTIIFVLSMLVYFFVLKTFLNVNLLDEVSKMISEIVNIQKNSFSATELKVFD
                     KMKPDEIVSYFTNMLPMMLFLQGLLSAFVTYYLSVFFIKRITKMNIRFPKFADFYLPG
                     NAILTTFLLYLLVLFIQIIGSKLYTELIMTNLQLVFNLMFVIQGIAVCIYFLKKWIRQ
                     GPNKIMFFSGIILCLFGFMGISFVGMVDSIIDFRKVRSYKST"
     gene            29126..31120
                     /locus_tag="PC512_000513"
     CDS             29126..31120
                     /locus_tag="PC512_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HDF2440290.1"
                     /translation="MSNKQTFKLNMPEINLYIIVIGISSIILLYYNLYVGCLFFCIFV
                     YMVFHNWRTTNIRRHEWTEYIQNLSLDIDETTKKAIINLPIPLCILEFDGNISWYNGK
                     FYDMIGQKDLLDKNIEDIVKNLNLRKVLNENKEMYTEINYKEKEYTIIYNVIKNDQEK
                     NPKYLMILYWIDKTEYLKVKQNYDDEKNAMMLIQVDGYDEVLKSAAEDKRALINVEVE
                     KILSALELNSNGALRRTSKDKFFLVMHKKELKKLEAEKFSILDTIRHIDYGNNLPVTI
                     SIGIGIDGDTLNENLKLATGALDLALGRGGDQAVVKTKDKFVFYGGKSKAVEKKTKVK
                     SRLIGHALREVIQQSDQVYIMGHKYPDMDAMGAAVGVYDICKSCNKTANIVLQSVNES
                     IEIFINKINENNYYKKLFIGKEEAIDNCTKNTLVVVVDTHRPNYTECEELLKLSEKVV
                     VIDHHRRGVEFINDAVLLFHEIYVSSTCEMVTELVQYMDEDVTINKLTAEGLLAGISL
                     DTKNFAFKTGVRTFEAASYLRKVGADTIEVKKFFNSDVKDFIIKAEIIQSTKIINNRI
                     CLAYSSTEIDSINVIIAQTADELLNIKEVEASFVLGEKDDTIFISARSLGQINVHVLM
                     EKLGGGGHIDIAGAQLKNVSLKEAYKMVNKIIEEYLEEEE"
     gene            31121..31570
                     /locus_tag="PC512_000514"
     CDS             31121..31570
                     /locus_tag="PC512_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HDF2440291.1"
                     /translation="MKVILLKDVKGTGKKGEMKEVSDGYARNFLFPKKMAVQADSVAI
                     KELNEKNKSKEIKAQKEYEEAVLLGKQMEEINIEIYSKAGEGGRLFGSITSKEIAEQL
                     KKQKDIDVDKRKILLDEPIRSLGSTFVEIKIHQKVTTKIRVDVKEKQ"
     gene            31589..32917
                     /gene="dnaB"
                     /locus_tag="PC512_000515"
     CDS             31589..32917
                     /gene="dnaB"
                     /locus_tag="PC512_000515"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HDF2440292.1"
                     /translation="MEDMTRIPPHSVESEQSILGSILLDKDAIITVTETIKPDDFYKE
                     AHKIIYECMITLSNKGEPIDLITLTEELRKQGHLNDIGGISYITSLSTIVPTTSNVKY
                     YADIVKEKSVLRKLIKASNEIINLGYSGATKIEDVLEQAEKSIFDISQEKTSDDFKSI
                     NLVLMDAYDMIEKLYTNKSDVTGITTGFKDLNKKINGLQRTDLILIAARPAMGKTAFS
                     LNLVQNAALKGDASVAVFSLEMSKEQLVQRMLSSQSSVELKKIKTGTLNDNDWPRIID
                     AMAVLSDAKIHIDDTPGIKISELRSKCRKLKIEKGLDLVLIDYLQLMEGEGNNESRQQ
                     EISKISRSLKILAKELNCPVVALSQLSRAPEQRADHRPMLSDLRESGAIEQDADIVMF
                     LYRDEYYHADSESKNIGEVIIAKNRHGETGSVELVWLGEVQRFGDKLRDL"
     gene            33122..33430
                     /locus_tag="PC512_000516"
     CDS             33122..33430
                     /locus_tag="PC512_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440293.1"
                     /translation="MEKISLKYIYPNIIKVLDEINLFRVIDNNLRESIVVYANNVDNQ
                     YHINMTNTNFGNIINICKLEKLLDVDKFMEKVIKYEKEIIEKEEFSKIEEYMLNIGEY
                     "
     gene            33512..34801
                     /locus_tag="PC512_000517"
     CDS             33512..34801
                     /locus_tag="PC512_000517"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HDF2440294.1"
                     /translation="MKTVAIVGSQWGDEGKGKVIDYLATQADVVVRGQGGNNAGHTLV
                     VEGKKYALHLIPSGVLNPNTVNIIGNGIVFDPKGFLEELEMFKTDNISTENIKISDRA
                     HVIFPYHKELDALSEEARGDLKIGTTKKGIGPCYMDKTERSGIRICDLMDKDKFAIKL
                     KAQIDAKNEIVKNIYGKEELFDFETIYNEYLGYAEQIRKYVADTSVIVYDAVRAGKKV
                     LFEGAQGTLLDLDLGTYPFVTSSHPTSGGFAIGAGIGPNMIKDVVGIVKAYTTRVGEG
                     PFVTEQINETGDKIREQGHEFGVTTGRPRRCGWFDAVIVKYAARVNGLTSISFMLLDV
                     LTGFDKIKVCTSYKMGDKIITDFPASLDDLAKCEPVYEELDGWNEDITQIDNFDDLPE
                     NAKKYVAKIEELVGVSVDMVSVGPNRAQTIIRRNIFA"
     gene            35127..35202
                     /locus_tag="PC512_000518"
     tRNA            35127..35202
                     /locus_tag="PC512_000518"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35160..35162,aa:Lys,seq:ttt)
     gene            35209..35283
                     /locus_tag="PC512_000519"
     tRNA            35209..35283
                     /locus_tag="PC512_000519"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35242..35244,aa:Glu,seq:ttc)
     gene            35288..35363
                     /locus_tag="PC512_000520"
     tRNA            35288..35363
                     /locus_tag="PC512_000520"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35321..35323,aa:Val,seq:tac)
     gene            35397..35471
                     /locus_tag="PC512_000521"
     tRNA            35397..35471
                     /locus_tag="PC512_000521"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35429..35431,aa:Thr,seq:tgt)
     gene            complement(35854..36846)
                     /locus_tag="PC512_000522"
     CDS             complement(35854..36846)
                     /locus_tag="PC512_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2440295.1"
                     /translation="MNEDKIRKILAKYAKRRDDNELLLEHRKNEVYNRIPEIKSIDDE
                     ISKIGLSLAKIVLLNPKSKDEIVKKTKENIESLKVKKERLLAESNIPLDYLEIKFQCI
                     SCKDKGFLPNGEKCSCLKQEIVNEAYKMSNLDRILSQENFSNFNLNIFSPKKGSDGEI
                     SPRENMLNNLSICENFVHDFKKDNSENLLFYGSTGLGKTYMCNCIAKELLDKGNVVIY
                     QTSFRILDILEDYKFRRDTNNQISEDNYKNLFDCDLLIIDDLGTELNNSFTSGEIFNI
                     VNTRLVAGKKIIISTNLTPSQIGNTYTQRTLSRILDKFRILEFTGDDLRWERFK"
     gene            complement(36855..37913)
                     /locus_tag="PC512_000523"
     CDS             complement(36855..37913)
                     /locus_tag="PC512_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HDF2440296.1"
                     /translation="MFFKESNEIDLGEITIPNIFIDIFMPMADGLYVKVYLLGYRQAC
                     DITSNPKFDNNSIAKNLNIPLSDVLSAWKFWEEKKIIKIHDNEEYDNFNYSIEFLDLK
                     NFYIENILSNNSSIKSNTDKVVSTSENPSIRKMFNSINKIVGRYLDPSEKMSIMDIMN
                     KYNMSPDMILCAYEYVKDKTGTSKPVKYIEGIIRNWYDSNLYTPKDVEESFLVRSERY
                     ILYKTIFNELGFSRQPSKSEKELMDTWFDKFNMDIDLIINACSKSKNISNPSISYING
                     IIKNWNEKNIKNLNDLKQKEEERIVKENINKKQINTTQNNNTYKKTKFHNFNETFTQY
                     TSDELDEIIKKSQKEKFK"
     gene            38038..39501
                     /locus_tag="PC512_000524"
     CDS             38038..39501
                     /locus_tag="PC512_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HDF2440297.1"
                     /translation="MVIKFNQKVRRTLSVAILFMVLIIGCFIEKDDSLETYKEKTNSK
                     INQYNMDVIFDDETKRLMCNQNVDYINNTKSNIDKIYFHIYPNAFSKKDFAPFEKSEM
                     TRAYPNGFNEGYIDIKNILNNNSKMEYKIKGDKNDILEIELGKELKPNERMSLDIKYN
                     VKIPNSIGRFGYGENTINVTNWFPIACVNDERGWNLKSYETIGDPFYSETSDFHVKLL
                     IPNKYKIAHTGKLIDDKHDNKKMLYEIEAENVRDFAFILSSKFDVNKVDSKGVAINTY
                     NLNKKLSKKATEVAKDSINIFSELFGKYPYKEFSVVASDFFIGGMEYPMLVMIDQSLY
                     NEKNEFLLEYVIAHETAHQWWYSAVGNDEISEPWLDEALTEYSTIVYFEQKYGKDMAN
                     KLIKTMEIQTKSYLSENIFKPANEYKNSTEYSLNVYTKGAIAFNEIRKEVGDKVFFET
                     LNEYYNKYKHKNANGRAFVELWNSKGVDINKIISECK"
     gene            39603..40400
                     /locus_tag="PC512_000525"
     CDS             39603..40400
                     /locus_tag="PC512_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2440298.1"
                     /translation="MLKYCSVGSGSSGNCHYIGYKNTNILVDAGLSGKRITTGLKDIG
                     VDADKLKGIFITHEHVDHIKGAGILSRKFDIPVFANIKTWCSMKDKLGDIKDKNMKVF
                     ENDKTYSLGDIIVRPFSIEHDASDPVGYNFYTESDEKMSIATDIGCITQNIKKHLYKS
                     KLVVLESNYDPNMLMMGSYTYALKKRVMSSTGHLSNEDAANFCVELINEGTESILLAH
                     LSKENNFPELAYETSKGVLASNDIVVGQDVKLDVLSRNDVSNVYEMK"
     gene            40413..42515
                     /locus_tag="PC512_000526"
     CDS             40413..42515
                     /locus_tag="PC512_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC/EAL
                     domain-containing protein"
                     /protein_id="HDF2440299.1"
                     /translation="MLKRNFENVEDNKILYSIKQGMILAIPAIMTGSTALVILNLPIK
                     AYQEYLSGLFNGEVTNILNFINDSTLGIISLIILLTISYSYGKIYGSKYTVLVPIVAM
                     CSFLVFSHGNELNSYIEIFKTKWLFTSIIVSMTSSVLFVKLTESFVTSVKFHTEGADA
                     DFNMVVSAIVPFIIVVFLFSIFRVVMISLIGSSNFQDIFYNLFSNVFNKMGTNLMSAL
                     LFIFLMHFMWFFGIHGSNVLDTVAKNLFENSMAININLVNNNQLPTEIFTKTFFDTMV
                     LLGGCGSLLCLVIAIFLSEKRINVRKLAKIASIPALFNINEMLVFGIPIVFNYIMFVP
                     FVITPIILTVTSYVAMSTGIVPCTVSAVEWTSPIFLSGYMSTGSIRGSLLQVFNLCVG
                     VMIYIPFIKMSQNRYTYMFKNNIENLTNLLKRYELTGEQPNLLNHNGKIGSISKMLAS
                     DLKFAMKRGEIELFYQPQVNYNGNVVGAEGLLRWKHSIGGFIYPPLVIILAKEEGFLD
                     ELGEYIINKACIDLKKSEKLLRNPVKFSVNISPDQLDDPKLPEQIKNIISSNDINPNM
                     LGIEITEQIALSGSQIIIERINAIHNLGIKLIMDDFGMGHSSLIYLQNNNFDIVKLDG
                     SLVKEILTNKRSSEIIMTIVNLSKNLDFDIVVEYVENIDQRDKLYGLGCEIYQGYYYS
                     KAIPFEEFVEYANQEREI"
     gene            42583..43062
                     /gene="rlmH"
                     /locus_tag="PC512_000527"
     CDS             42583..43062
                     /gene="rlmH"
                     /locus_tag="PC512_000527"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HDF2440300.1"
                     /translation="MNISIVVVGKIKEKYLKLGIDEFKKRLSKYCKLEIIELDDEKAP
                     ENLSVKEMEIIKDKEGKKILGKIKHNSYVIALAIDGKGLSSEELAKTMSDLAVRGNSS
                     LCFIIGGSLGLSDEVLGRADYRLSFSKMTFPHQMMRLILLEQIYRAYRINNGEPYHK"
     gene            43211..43522
                     /locus_tag="PC512_000528"
     CDS             43211..43522
                     /locus_tag="PC512_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2440301.1"
                     /translation="MIKIMLACSAGMSTSLLVTKMESAAKENGIESQIWAIPESTIQN
                     EIEKCDVLLLGPQVRYVLPKAQEIAKPYNIPVEVINMMHYGTVNGEAVLNRAIELNNT
                     K"
     gene            43570..43887
                     /locus_tag="PC512_000529"
     CDS             43570..43887
                     /locus_tag="PC512_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDF2440302.1"
                     /translation="MDEKTIEISFNIIGYAGEGKGLAFEAIKEAKNGNIEKAKELLKE
                     SREVINKAHRYQTELIQNEASGNRTEISVILIHAQDHLMNGMNFQQLAEEIVDLHLKL
                     QDK"
     gene            44100..44801
                     /locus_tag="PC512_000530"
     CDS             44100..44801
                     /locus_tag="PC512_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2440303.1"
                     /translation="MLRNQPLYIQVVDILKQKILNNEYKIDENIPTERELEQEFGVSK
                     ITIRKAIEILESEGYVEKKSGKGTKVISNSLFNKLSKAESFSSILLSKGHKLSKKTIS
                     IEKIINDTNSQVFSIFGEKCSKITRMYYLDSKPYIFFTHYIPFDENLTVESFNNESSL
                     YMYLYRRNINITRFEDEFFIEESELEVSKALNLAKDILLGRKRKTYDENDNIVELSFA
                     RYNTEVQNYVIKYEI"
     gene            45025..46326
                     /locus_tag="PC512_000531"
     CDS             45025..46326
                     /locus_tag="PC512_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2440304.1"
                     /translation="MEKFASFLERKIMPVAAKISNQRHMRAVRAGIIATLPLTIVGSF
                     FTILLNIPIDAYMDFIAPFKAILDIPFRYTVGFLSLYATFGIASSLAKSYDLDTTGVG
                     MLAVMAFLVSTIVPTQVVEPVGGVIEAGRWMDMAKLNSPSLFGAIVTSLITVEIYRFM
                     KEKNITIKMPAGVPVEVSNSFTALLPTAVILMLFWVIRHILGFDISVALSAMLSPLKG
                     FLSGNSLGGGLLTVFLITLFWVLGIHGPAIMGPVIRPIWDMSIAENITAFTEGVSAHA
                     MPNIFTEQFLQWYVWIGGAGATLALVVMFMFSKSQYLKSLGRLGFLPGLFNINEPIIF
                     GAPIVMNPILGIPFIIGPIIMTILSYVLTITGVIPMMVARLPFAMPAPIAAVMSTNWS
                     ILAGILVLINFVISFAVYYPFFKVFEKQQLQREQEEMSENL"
     gene            46463..47557
                     /locus_tag="PC512_000532"
     CDS             46463..47557
                     /locus_tag="PC512_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HDF2440305.1"
                     /translation="MERRLGISVYPEHSNMEDDKAYIKMASKYGFKRIFMCMLSITRP
                     KEEVKKHFKEIITYARELGFEVILDIAPNIFDILQISYDDLTFFSELNASGIRLDYGY
                     DGSKEAMISFNPYDLKVELNMSNDVAYLDNIITYKPNVNNIYGCHNFYPQRGTGLPYD
                     FFVRCSNRFKKYGIRTAAFVNSKYATIGPWNINDGLCTLEMHRNLDIATATKHLFATG
                     LIDDVIVGNAYASEDELKRMSEVNKYQVVFNVVTEEKTSEVEKTIMANEQHFRRGDIT
                     NQVARSTEVRKKYAKENFPKHDNTTIFKRGDVVIGNDDFGKYKGELQLILQDCADERK
                     NKVGRIKEDEIMLLDFIEPWSKFKLILEGE"
     gene            47559..48692
                     /locus_tag="PC512_000533"
     CDS             47559..48692
                     /locus_tag="PC512_000533"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase/deacetylase family
                     metallohydrolase"
                     /protein_id="HDF2440306.1"
                     /translation="MKIDILIKGGKTVDKSIIDIAILDDKIIEVKNQIDDSKYQANQI
                     INLDGEKFISAGWIDIHTHCYERLDLYKDYPDEVGIKSGVTTVVDAGTTGALDIGKFY
                     EDTKKYKTNVYALINIAKQGITSQDELSSMMNIDEYELKRAVKKYKDFVVGIKARMSK
                     SVVISNDVEPLKVAKRIKNELNLPMMVHFGSSPPTIEDIFDYMEKGDILTHIYNGKPN
                     GILRGNEVKKEIIEARERGIILDVGHGTESFSMDIAMKSKDAGIFPDTISTDIYIKNR
                     INGPVYNLSTTMEKFIYMGYSLEDIIDKVTKNAADAISLKNKGLIKEGYDADLTIFDV
                     VNEEKELQDSLNKSVITSTSIKPRAVVVNGEYLNIGKSIGENE"
     gene            48710..49819
                     /locus_tag="PC512_000534"
     CDS             48710..49819
                     /locus_tag="PC512_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DgaE family pyridoxal phosphate-dependent
                     ammonia lyase"
                     /protein_id="HDF2440307.1"
                     /translation="MSSIFEKYSVRRVINASGKMTILGVSTVDKEVIEAIGEGCKNFF
                     IIEELINKTGEYIANLLGCESALIVSSASAGIAQSVGAMIAKDDMSLVYNVNNPKKQV
                     KREIIIPKGHNVDYGVPVEVMIRLGGGEVVEAGYANMCNKEHIIREINENTAAIMYIK
                     SHHCVQKSMLSVLDAVQVAKEYNLPLIVDAAAEEDLNVYYELGADLVIYSGAKAIEGP
                     SSGLVIGKKKYIDNVKLQSKGIGRAMKIGKENIVGLTCAIERYISNDKVTLKEMEDKL
                     NPFIDKINTIKGVSASITRDSAGREILRGEIDFNEDIINKSTQQIINELRSGEIAIYT
                     RDYKANEGKIEIDIRSVTGSDLDTIYNRIKNIVES"
     gene            49884..50624
                     /locus_tag="PC512_000535"
     CDS             49884..50624
                     /locus_tag="PC512_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KDGP aldolase family protein"
                     /protein_id="HDF2440308.1"
                     /translation="MNCIPQYYKNRVCLNVLAGSIKNAKEVYDACDGYVLIGVLSKNY
                     STVEAAIEDMKKYSKEIDNAISVGLGAGDPNQSNMVSQISKELQPQHINQVFTGVATS
                     RALLGQNDSIINGLVSPTGKPGFVKISTGPLSSKEKDGIVPIETAIAMMKDMGGSSIK
                     FFPMGGLKTKDEYIEVAKACAKHNFYLEPTGGIDLDNFKEIVQIALDAGVEKVIPHVY
                     TSIIDKETGETKVEDIGVLYKIMKELLG"
     gene            50629..51621
                     /locus_tag="PC512_000536"
     CDS             50629..51621
                     /locus_tag="PC512_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HDF2440309.1"
                     /translation="MNILAFGEIMMRLSVPDYKFLTQTNELNYIITGTGLNILSGLKN
                     FGYNTYMLTKLPNNNVGKASSANIRKLGVKDDFITYGGNHIGVYFLENGYGERPSEVT
                     YLNRLNSSFCESKLQDYDIDKCLEEMDIVLICGIAMQLTDSIKEIALELARKSYEKGI
                     KVFFDFNFRQSLNPERTYDDLVNDYKKILPYCHGLFASYRDINKILNIDSLNIKSSSE
                     LIKKEYDIGIVAGTMRRFDDMNNRFIKGYISNDDGYFESREYKLEIYDRVGAGDGYVA
                     GIIYSYLENMKSEDIVEFGVASSVLAHTTYGDNSLVSTGHVLRLMNNEKIDILR"
     gene            complement(51809..52690)
                     /locus_tag="PC512_000537"
     CDS             complement(51809..52690)
                     /locus_tag="PC512_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF2440310.1"
                     /translation="MNTKQLEYFISVAENLSFTKTAEKFYISQTAVTQQIKALEEQIN
                     VTLFTRSKRHVELTPAGKVFLSEARTIIKNINDAIAKTQQFAHGFFGTLSIGTLIGYE
                     KNKLQQYLKEFSNTYPNISMDICTNEITELLNLVKNNSMDLAFVINPENQPLKDFEYK
                     TVERYSLVALLPPGHPLYNEDSIDLIELQHDKFIFVKETGDEYGQKSMIQNRYREAGF
                     VPNVVQRSNNLNTIESLVSSNMGISILPSFCVTDTMIERDIAIVPIKEVENRIEVVVV
                     WNKKNTNPALEKFISII"
     gene            52963..54351
                     /locus_tag="PC512_000538"
     CDS             52963..54351
                     /locus_tag="PC512_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440311.1"
                     /translation="MEDKFYAKGNGNNGYIKNLEVCSFNNLDGTCGMFQMALYKRDEK
                     YYLYGCCFGGNKKNGVMISDITDPYNPQFIKHFQMLDPKEYPTTTTPKIQIADDLMIV
                     AMSCGSGPGALVDQAKLANIKCEAGIRIYSLKEDPLNPKFLGYWDCGLKHVMGVHRFM
                     YNGGRYVHLSSDCVGFEGLIYRVIDIINPTNPVEIGKWWRPDQYADGYPNRTFDAGAP
                     HCPEFMDKGWLHGPPFVRDGKAYCGYGGAGLVVLDVEDLTRPRCLGELPFMPAFSSRL
                     AGARTHTALPLPGRDLVVVQNEGERFQFFKPDNITDVQAMNNIHMVDVSDPTKPTLIA
                     QFPYPEVPKDFPYPNFNVAGLGKPGPFGPHNLHEPMDNKPWLEQRGDRVYCCYFHAGL
                     RVYDVSDPYYIKELAYFIPPNPNKTPEESYFPGFPGPRLAVTEDLIVDDRGYIIIDAL
                     DDGFYILKMKED"
     gene            54379..55332
                     /locus_tag="PC512_000539"
     CDS             54379..55332
                     /locus_tag="PC512_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HDF2440312.1"
                     /translation="MKILGISFGTKNGNNDTMCKVALKGAKEAGAEVEFIQMSSINIK
                     HCTGCCACVKTLLSGKGSMCVLKDDFEWLLDKMKDADGIVVSDPIFEEGASGLFHTIM
                     DRFGPRADRGNNIIGTKVAEAIGGKIPDSRMLNDKVISFMGIGGSDWGTRVQCEHAML
                     ALIPMWKVIDNAWFPWAKELVMDDTRLVQVHQIGLNIVEAAKDFEKASYQGEEGVCPH
                     CHNRLFYLEPGTKKAICALCGIVGELDTISGKTIFSFPEEQLGHAHDTLPGKFIHGDD
                     IKKMEGHYAEVRKTQEFKERKTSYNFIETLTKEKQAGVSLG"
     gene            55392..55616
                     /locus_tag="PC512_000540"
     CDS             55392..55616
                     /locus_tag="PC512_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440313.1"
                     /translation="MNEKPSFKQIEVILAVIFLVLTYYKVRLTPAFIVIFIPLYLSYF
                     AVSMIVNQIAIKLLEIRQAREATNYNIGNG"
     gene            55609..56121
                     /locus_tag="PC512_000541"
     CDS             55609..56121
                     /locus_tag="PC512_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1097 domain-containing protein"
                     /protein_id="HDF2440314.1"
                     /translation="MDRKKKEILTLSMGIALLPPLWAVLAPYIGIKTGAVALICAGLY
                     VTNGNKQEDGLKIMFGFWCGDLWAVLAILIMGYMNFNQNLELFLTLSILGFFAVVIAS
                     LFEKIIFLPSWLCGWAIGLTIMTGENIINLQDICIQIAVAMAVGVWYVGAGVDLFTIY
                     ILSKDRKKGN"
     gene            56153..57007
                     /locus_tag="PC512_000542"
     CDS             56153..57007
                     /locus_tag="PC512_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase"
                     /protein_id="HDF2440315.1"
                     /translation="MAMGFEFKIMRSLIYVGLAKEEYRPKLMDWLYRHHIPDSISTFG
                     PYCTKYAFYQAYPTPNEGERFGARKMQLTEHYWLVDEHMPEMANRIMTEYMPMDVLRW
                     QGCIPDVENKRVHENAESGDAGRAVGGDNGCPPFIFAFVPINWEEDFRGKGRTVQDGP
                     NYRWQFMIKYPDGISKEEGEKWFYDEVVPYFTNCCYVNRFVSSKIMINYGATAFDRVS
                     ELWFEGEEEWYKAVVEETKSFIKKPEWAQEEEFPYLKPQFNIASVFLGDIATMDAYSQ
                     YRGYIPMR"
     gene            57541..58335
                     /locus_tag="PC512_000543"
     CDS             57541..58335
                     /locus_tag="PC512_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2440316.1"
                     /translation="MYTIGQVSKFLGISRDTLKFYEDKGLVNPKKNDENGYRIYNQVD
                     IYDIATINFYREIDIEIKKIQEIRKSKSINNLELLLEEKEQIILKEIEYKKLLLKKVQ
                     LVKEDCDKIKTYFGKYTIKEMKPLEVKGKIKHVTNYEEYEALKENTNNLKKAVTLTDL
                     RRVINFNEEGIIEEKFIIVREVDDYNKIIEGEVLSHPNCIYTIIEDGRWSTGGENIDN
                     KVEDRLREIAIENECELLGIVYVNILLTTYEEGIERIFLEIYAPIK"
     gene            58439..59245
                     /locus_tag="PC512_000544"
     CDS             58439..59245
                     /locus_tag="PC512_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDF2440317.1"
                     /translation="MRTEKSLKRPIASFIILTNIIFLPLFLLVVVTIMLKLPTVISDI
                     ALCISAWSSTFAFMILFKKIYPGKKFLVHVKDRFRNKLKFSTVSIIISIQVLIAVVVI
                     FILASKNHGIMPNFTVSSWGAFIYLFLKNLFAGSLGEELGWRGFVQNHLQKRHSPLKA
                     SITVGFWWGMWHLPIWFTTGFKGLDLIKYIIFFMIAIISISIIMTTFYNLNKTLIIPI
                     AIHQLFNFLIGIINEDLIELINYYAMLYLIFAIALIVINPGNVLYKNIRE"
     gene            59307..59828
                     /locus_tag="PC512_000545"
     CDS             59307..59828
                     /locus_tag="PC512_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003374619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HDF2440318.1"
                     /translation="MVLLIVDAQKLITNERLYKFNEFVVNVENLIDTARKNNIEVIYV
                     RHDDGVENELTKGKNGFEIYEKFKPCNGEKIFDKKVNSAFKETGLLEYLTNNGEKDII
                     IAGLQTDYCIDATIKCGFEHGFNIIVPAYSNTTVDNFFMSAEQSYKYYNEFIWNERYA
                     KCISLEETLRKMK"
     gene            60243..62330
                     /locus_tag="PC512_000546"
     CDS             60243..62330
                     /locus_tag="PC512_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF2440319.1"
                     /translation="MVVDKEIVSILQILLNSTLITTNGLQEESNSSKRQITYRINKIN
                     DMLKVKNVPLICLRADKDIIVRKETKKAIKEILEKNYSKNTYYFSKTERLLYMYLMLF
                     INMEDISINHFINSIKVSRSTVNLDFKDLIPELEKKNIKVKNNRINGYYIVGNEMEIR
                     RVLIKNIIETLSNEKSSRVFDIFIKEYNLDSFEEAKKIILKLIKKYEITFVEDRLIEF
                     IYIFIFLKARMYSTRIVTQENVDIPNISVMSSMKEYKFAKELLEVYGSEDKIKPHNIM
                     YISAWILGISVGNYEEDTEDKDVISKIVNKMMTKFGYLSGVYYISQEKIFKQLYSHFR
                     PAYYRLLFKLPIYNPICEKVKEEYKLVYRIVSNAMKEFCGLFGEEIQEEELAYLTMHF
                     ATLFSNKKEFDGFRKRIALIVCSNGVGSSAILHAELTNLFPDLHFIPMSESVGLENIS
                     EPVDIVFTTNYNAEGLKTDVPVIKVSPVMTTKEKYKITREVYIQLGDIFLRQPKIDEV
                     MDIIKKYANVTSESILSSELLAYFTQIENFTSKEGEGPMLSEITNETLVKIKVKAKNW
                     EEAIRQSASVLVENNKVTEGYVDAMINSAKASGPYIVITKHVALPHARPEAGSKEIAI
                     GIATLDSPIEFGNNENDPVKYVFCLSAIDNNSHLRAMSELVELLEEDEFFKVLDSAKE
                     AKEIIDFIKTHEL"
     gene            62345..62632
                     /locus_tag="PC512_000547"
     CDS             62345..62632
                     /locus_tag="PC512_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2440320.1"
                     /translation="MYKILIACRAGVGSSLMLKIKTQQIIKENNFPIEVEHGSLDSLN
                     GFNGDAVETLIDVAEELKNKNLKFDIIGIHNIVDRNEIKTALEKFLASKEG"
     gene            62659..63930
                     /locus_tag="PC512_000548"
     CDS             62659..63930
                     /locus_tag="PC512_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HDF2440321.1"
                     /translation="MEFIISLLSTPAVLLGVVACIGLILQKKSAVEVFTGSSKTLIGF
                     LIFGIGASAMTGALQNFNKLFQHGFGITGVIASPEAATALAQGTYGFAVSCTLILGFI
                     LNLVFARITKFKNIFFTTGHSLFFSCVLVLIMKAHGFDNTITILIGGTILGFMSAALP
                     QFCQPFMRELTGGDEQAIGHFNMIGYGLSGYIGRLFSKHKDDTTETIEFPKWLSIFRD
                     FLMGLSIVMLILFYIATLKAGQAFTQEIAGSTHWLVFPLIEAFTFVAGMSILMSGVRM
                     FLAEITAAFVIISEKYIPGSRPALDVPTVFPYAPNAVIIGFISAYAAGLLAIAIMASF
                     PSIFPVVIIPAAHICFFSGGTAAIFGNTSGGWRGAIAGSFVVGLLLAFLPVILYPVYG
                     TLGIEGATFPNIDYNVVGSILHNILQFIKPI"
     gene            63988..64587
                     /locus_tag="PC512_000549"
     CDS             63988..64587
                     /locus_tag="PC512_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDF2440322.1"
                     /translation="MENTLSEFLDNISNELSEFIASIDETSINKACELILEAEKNHGR
                     VHVTGIGKPGHVSGYISSLLSSTGTSAYILHGTEAVHGSSGQVVEGDVVIAISNSGET
                     QELKATLKTLKVNGAKIIGVSGNESSFLKNISDIFLFAGVKQEGDCLNKAPRASILAE
                     TIILQSLSVVLQYAKGLNTQQYLKWHPAGSLGKSIREGI"
     gene            64592..65497
                     /gene="dapA"
                     /locus_tag="PC512_000550"
     CDS             64592..65497
                     /gene="dapA"
                     /locus_tag="PC512_000550"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HDF2440323.1"
                     /translation="MKYKGIICAMITPFDENQNINSQATCQLIDYLIEKGIYGLFILG
                     TNGECHVLTDDEKVEFAKIVINHTNNRVPVFVGTGGNSTREVVDLSKRMEAIGASALS
                     IITPYFVTPTQQELILHYKTIANSVNLPIIMYNMPSKTGINIEPESVRELSKIKNIVG
                     IKDSSGKLDNMKAYIEATKNENFSVFSGSDSLILDSLKAGSQGAVAATTNFLTEIGIS
                     IYENFMKGDLEEAQKAQSSIEELRRILKLGTIPSVMKKTIVLNGINVGTARLPVTEPT
                     GEVLEEIKRVVENYRTILNKSSENR"
     gene            65603..66235
                     /locus_tag="PC512_000551"
     CDS             65603..66235
                     /locus_tag="PC512_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketohydroxyglutarate aldolase"
                     /protein_id="HDF2440324.1"
                     /translation="MKKMNITKRMSECGALAIVREENLNRACEIAEGCIKGGITVIEM
                     SYTLNNAGEIIQGLNKKYGETLCVGAGTVLDSETARHAILHGAQFIIAPNYNEGVAKI
                     CNRYQIPYAPGCTSLTEAVDALSLGATFIKAFPISDFYGPKLVKVFKTPIPDMPVLAS
                     GGINIENLHIWLENGVDVCGFGGLLTKGSVEDIAKNAKKIREIIKNIRKI"
     gene            66713..69220
                     /locus_tag="PC512_000552"
     CDS             66713..69220
                     /locus_tag="PC512_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDF2440325.1"
                     /translation="MKEDIRLHRMCKKEQATKNEVISEDILKSMSIGVSKHFLDDSFT
                     IIWGNTSFYQLLGYTEEEFLVKFSSLKDYYEQNLYHFESMKNHFLEAYHHGEKSIEYQ
                     ICISANNGDPVWVIMTGILIESQDNEKSMVYILYSKINELKIKQEELSDMEKESTENF
                     KWMMSEYAGNVYISDMDTYELLYLNKHSCNTLQASANELIGRKCYEVIQGRTSPCPFC
                     TNSYLKKDDIYEWEFYNKKLKRTFIIKDRMLNWQGRRVRIELSYDMYSAEYKLAKKDQ
                     ERESILKTIPAGMVRLDARDYLTILWCNDIFLNMIEYTKEQFAEELNNQCGYLFSEDY
                     KRSKKLAQDLKESGDNVVFEAKIYTRSREERIWTVTLCYISGEDSWDGIPSFYSIGID
                     ITKERKQIEKLQHISEKDALTGIYNRAETERQIKKYFEKNLNVMGALFMIDTDNFKQI
                     NDTEGHMIGDIVLTEMASGMKKIMRDSDVVGRIGGDEFTIFMKNISSVKDAEKKAEEL
                     LYMFRHLFQKEKSFLKVTCSIGIAIYPKDGTTFKEIYARADKALYQAKNMGKNNYVIY
                     NQDYFKELEEFDCSSLGTVIDSEKQYAEYPDNLTRYIFRMLYQTDDIDQAINMILEVV
                     GKQFDVSRVYIFENTEDGRYTSNTYEWCNEGISSQMAYLQNSNYQDYEDYEKLFEDEL
                     VFYCRDIHTLSPKLEELFSSQGIHSTLQCAYKEDRVFSGFVGFDECTGLRLWSQEEIS
                     TLSLISQIISMFLQRKKNNKLNQQIQQYQNILDNIDQCICVINKENNFLLYVNKKFKN
                     TYSKFQIGQPYYLDSIDIHKISIIWNKKEAYLCTSTI"
     gene            69562..71724
                     /locus_tag="PC512_000553"
     CDS             69562..71724
                     /locus_tag="PC512_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HDF2440326.1"
                     /translation="MKKIIYVLFTIELLIVSLLGLNIVKDNEINNILYNETTSISVMF
                     KDYKKLNKNYSKWIKDIADENNVTISKYVFNNNEKLSIYTTDTSLNNNIKLKSGKFPN
                     TNSNEFISNINTNNSNQVGKFSTMSKDISILIRDFGKISEVGESGILYISTQNEDTIN
                     KILRELNVDRSIFVARLHDRYVNSNLYLNPSIIRDLILIILCFLATIIHYSISVSREA
                     SILRLNGYSKLDIIARVIKNILRIMILSSVTALLIYIIYILKLNIGVRACLYFAMFSI
                     ICILINILISILIVGFNSRSSKYVLSLNGKKSYGFVNIMHFTLKIVFVSFLILSINNC
                     ILNYNMLQTQLGNLSEWDKAKNVYNLTLKDTGEQSLGKEEVIKNAKIKGFYKNLVEEK
                     DAFLIDSTNFEKLEDGSYMYEINSKGKNPEVSQYGKNIKINKNYLKVNPIYSNGKEIF
                     NLIDYDDKTINLLVPKKLQVHENEIKKEFRELFYFEKIEVENMYNKELNRALNKTKKS
                     DLNVNIIYVDNNQSYFTYNSLVMDDNRNLIDDPIAIVDIDNIDDSFYLSYISRCVYFN
                     SKKLDALADISSIIEAQGVEAHIQSLHAVYNEYGLEINKLEKYLNSEIFTIIIIAISN
                     LMITYNIVASYYERNKYKLYIKKIFGYSTTARSMLLIVSLILTNIIPIGIISTRVDLS
                     NNIILFGLLILVIEVIVSIVLDKIISNSSFNKIIKGEH"
     gene            71729..72346
                     /locus_tag="PC512_000554"
     CDS             71729..72346
                     /locus_tag="PC512_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2440327.1"
                     /translation="MISLINISKKFKDKSIIDKFNLEISKGEFVAITGNSGSGKTTLL
                     NIMGLLEKPNSGDIIINNIKNPNSKQIRILQRDFYGYLFQNYALIENENVENNLKIAL
                     KYQKNINHNKKINYALESVGLRKYNKKKIYELSGGEQQRVALARVILKECEVIFADEP
                     TGNLDKKNRDIVFDILKSLNKNGKTIVFVTHDLELSEQADRVIKL"
     gene            72535..72879
                     /locus_tag="PC512_000555"
     CDS             72535..72879
                     /locus_tag="PC512_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HDF2440328.1"
                     /translation="MENLPNCPKCNSEYTYEDGTLLVCPECSHEWALGLGAEEDSNII
                     KDVNGNVLNDGDSVTVIRDLKVKGSSSSIKIGTKVKNIRLIHDSSDGHDIECKIDGFG
                     AMKLKSSVVKKA"
     gene            73449..74315
                     /locus_tag="PC512_000556"
     CDS             73449..74315
                     /locus_tag="PC512_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HDF2440329.1"
                     /translation="MIDIHKNIYDNKLFEELKIDCKKCFGLCCVALYFSASDGFPIDK
                     ESGKPCINLQPDFKCSVHNSLMKRGFKGCTAYDCFGSGQKVAQVTYKGIDWMQSSELT
                     NQMSEVFLIMRQLHEMLWYLKEASVLNISDTIKSKIDLIIEETEKITNMSPEQIINLD
                     IISHRIKVNLLLSQASESVMGKVKSFIKTSTLKNMKKLSKNIDLIGADLRKINLIGAD
                     LRGRFLIAANLRNTDLSGANLIGADLRDCDIRGANLENSIFLTQLQVNTAKGDSSTKL
                     PASLIRPKYWEK"
     gene            74428..74832
                     /locus_tag="PC512_000557"
     CDS             74428..74832
                     /locus_tag="PC512_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmaF family protein"
                     /protein_id="HDF2440330.1"
                     /translation="MSYQNYKCERDYVYDDYKYNKCNKCYNDYEEMTHVHEYSESVKL
                     AEECEDRHNHRAAGVTGEAIPINGGTNHVHKINDNVDFLDHFHKICVTTGPAIRIPGT
                     DKHIHLICGETTVNDGHCHKFLFTTQIEAPLV"
     gene            74999..75448
                     /locus_tag="PC512_000558"
     CDS             74999..75448
                     /locus_tag="PC512_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2440331.1"
                     /translation="MKSGIILEMKQINSTEYDEMLQVWESSVRATHDFLTEKDIESLI
                     PLVEIGLKEVENIVCIKDNDIIKGFIGIDKDKIEMLFIEDKYRGNGIGKKLIKYAIDK
                     YNVKYVDVNEQNKKAVGFYIHLGFKVFDRSEIDGQGNPFPILHMKLI"
     gene            complement(75604..75981)
                     /locus_tag="PC512_000559"
     CDS             complement(75604..75981)
                     /locus_tag="PC512_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDF2440332.1"
                     /translation="MLTPYLIFNGTCEKAFNFYAEAFGGGKTIFARLDSNPNNPIMHA
                     SVTFTKYEGCIMGADTDKPVVISGMAICVVLPSREAIEEISVKLAEGGTLVQEFLPHP
                     PPHQNDGAAEVLDRYGYTWYLST"
     gene            76243..77160
                     /locus_tag="PC512_000560"
     CDS             76243..77160
                     /locus_tag="PC512_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2268 domain-containing protein"
                     /protein_id="HDF2440333.1"
                     /translation="MVNMNIIEIRSDKIYKKIMDAPINKKEDIYRYELMKPFEFKWKC
                     MNVPIVARQKGGYDVIIASEMLGVLSPKDIDEKQKKNINVLSADKIWATCKETIENSI
                     NAFIKEGYDLNIKDYKYSILLANPNSPYTILSDGYWGDGGIPGYIFLSLVPNEYTINR
                     LPVLIAHECNHNIRFQFIEWNNNITLEEMMINEGLAENFATWMFGEEMLGPWVSRTDI
                     ETLNTYIKPIIKSALKETGFQNITSYLYGDDIAKMQGYFPVGLPYCAGYACGYYMIKY
                     YLEKTNKSIIEATLLPYSEIIEAVKEFWE"
BASE COUNT        29649 a         9148 c        12872 g        25743 t
ORIGIN      
        1 atataaatta acctactgtt taattttcaa tgttcgtgtt tatttcttgt tccttttttc
       61 aaggacaagt aatactatac catctttaaa acagtaggtc aatacttttt ttatattttt
      121 ttataaattt ttttcatatt cttttttcag cttctctact acctttttct ctagtctaga
      181 aacagtcatc tgtgatatcc ctagttcttt agctatacta gattgtgttt tatcaaagaa
      241 aaatctatct ttaaaaattt taacttctaa ttcatttaaa gtttcaataa acttattaat
      301 aaaatcttca tactctatac ttccaaagtt accttcttct tttccaatct tatcaataag
      361 agttatatct ttatcctctg aatcatcatt acttgatgaa tccaaagaca ttggttgata
      421 tccataagaa gcctccatag cctctaaaac atcttcttca ctaacgccta tataatcagc
      481 tatatctttt acctttggat gcttcttatt ttcttgttct aatttaatct tcgcatcact
      541 tatctttttg cttaattcct gtattcttct tgggactcta agtgtccata ctttatctct
      601 aaaatacttt tttatttctc ctactatagt tggtgttgca aagctggaga actcaaatcc
      661 tttctcaaca tcatatctat caatagcata aattaatgcc aatgaagcaa cttgatatat
      721 atcttcaaaa tcaacacctt tgtttatata cttcttagct aacaatcttg ctaaatacag
      781 atgtctttca ataagaatat ttctaatgtc tacattttta tttttattat ataaattaaa
      841 tagctctttt gtatccatat ttaggtaatg tgtagcatta gctacatttt tcattaaata
      901 tcaactccta aatatttagt catttttatt tttgtccctt gattatgttc tgattcaata
      961 tctacatcat ccattaaagt tttaattata aacaatccaa gaccactctc ttttggattc
     1021 tctaaatctg gtgtacttat tgagctaaca tcatatcctt ttccattatc ttgaatttct
     1081 atattaattg cattatctaa aatattaaat actatattaa atacatcatc tttactgtgt
     1141 tttattgcat ttgtacatgc ttcagatact gctaccttta tatcttctat atcatctatt
     1201 ggaaaaccca tcttattggc aattccagat gctgttaatc ttattatact aacataatct
     1261 ggatttgtag taatttccat ctttatagtc tcacaagcca aagtttatcc ctccacttta
     1321 aatattttat ctagacctgt tatagtaaaa atctttctta cgttactctt aggatttact
     1381 atgtatatct ctttttcatt tatttttaat ttttttaata cacctatcat agctcctaag
     1441 cctgttgagt ctatataatc taaatcttta agattaatct ttacatctaa catatttttt
     1501 tctattaaag catgtaaatg ttcctttagt ttatctgctg tagaaacatc aagttctcca
     1561 tcaagacaaa cattccaaaa tttattttgt gaatctaaat ttgaatcaat attcatagac
     1621 atgtaaaaac ctcctatttc cttttaataa ttttaaatat atttcctata ctcaatattt
     1681 tattaattac ataaactata tcatctattc cctttgatat tgatgatgca ttttcaacaa
     1741 tatcttgtat atgtctttca ttataatcta caatcttata tgccttttca acaaccttat
     1801 ttatgctgtt tagagtttta gctaaataaa ttgctactat aagagcagag cttcctacta
     1861 acactgctcc aatttgccac ccccatgcat tcattagtta acatctccct catcatcaaa
     1921 gcttttactt attactatat cttcttctga aatctttata tcttcttcat tattatcatc
     1981 atccactaaa tttattattc tctctttaac atcattaaat gtttcatgta gaacttcttt
     2041 tggattttct ttaacatcat taaacttctc ttttgtttct tttcttagtt cagaaccttt
     2101 tttaggtgca aaaaacatac caaatataaa ccctaaaata gctcctaata ataaaaatcc
     2161 acctttttta caacttcttt tattgcacat aacaattact cctttcaatt ttaaattttt
     2221 atctaactac attatacaaa aagaatagga tatttatcct attcttcttc aatatttatt
     2281 ttggcaatcg aaactacatt gacttcatca ttcgtcttca ttaatttaac accacttgta
     2341 actcttccaa acagtgatat ttcattgact cttattctaa taagaactcc atcagaattt
     2401 ataatcatta tctcatcatc ttcgttgacc atatctgcac ctacaattgt accagttttt
     2461 tcagatatat tataagtttt aattccttta ccagctctta tttgacttct atactcttct
     2521 atatttgttc tctttccaaa accattctta cttacaacta acacatctgt acctttactg
     2581 caaaggttca tagacacaac aaaatcttct ttacttaaag ttataccttt tacacccatt
     2641 gctgttctac ccatatatct tatatcattt tcatcaaatc ttatagacat accttcttta
     2701 gttactaaaa gtacttcttg ttttccatct gtaagttcta ctccaataag ctcatcatca
     2761 tctcttaaac ctatagcaat aagaccagat ttatttatat ttttgaactc ttctctctta
     2821 gtctttttaa caataccttt tttcgttgca agtaataaat attcattttc atcattacca
     2881 tcaataggta ttagagtagc aattttctca tctgctgaca attgaagtaa attcactata
     2941 gcagtacctt tagcctgtct cttaccttct ggtatttcat atgcatttaa tttaaatact
     3001 ctacctttat ttgtaaagaa taatagtcta ctatgagtag ttgtagttac caagtgcctt
     3061 acaaaatctt cttctctagt tgtaagtgct gaaatacctc ttccacccct tttttgactc
     3121 ttataagtat cagatggaag cctttttata tatccaaagt gagtaagagt tattgctatt
     3181 tcttcatcac ttataagatc tctcatatct atttcgcctt cagcatgtct tatttctgtt
     3241 cttctctcat cagagtaatt ttcttttatt attgtaattt catcctttat tacatttaaa
     3301 agtaatcttt catcagctaa aatctctttt aatctattta tcttcttgat taaatcttca
     3361 tattcagctt ctatcttatc tctttctaaa cctgtaagtc tttgaagtct catatctaat
     3421 atagcttgtg cttggatttc agttaatttg aatttttcta ttaaacctag cttagcttct
     3481 tgcccagtct ttgaagctct tatcaagctt ataacagcat ctatattatc taaagcaatc
     3541 tttaatcctt ctaaaatatg tgctcttgct tcagctttat ttagttcaaa tttagttctt
     3601 cttgtaacaa catcttcttg atgtttaata taatgatata atatttgttt aagatttaaa
     3661 actcttggct gaccatctac aagtgcaagc attattatac taaaagtatc ttccatttga
     3721 gaatgtttat acaaattatt taatactata ttagcattag catccctctt taattctata
     3781 acaattctca taccatttct attactttcg tctcttaggt ctgatatacc ttctattctc
     3841 ttttctttaa ctaactctgc tattctttca accagtttag ccttatttac ttgataaggt
     3901 atttctgtaa ctattatttg ctgttttcct tttggtagct cttctataaa agctctagac
     3961 ctaactttaa cttttcctct tccagttctg tatgcttctg ctatactttc ttttcccatt
     4021 ataattgcag ctgtagggaa atctggtcct tgaacaaatt ttattaaatc atctacacta
     4081 cactctggat tatctatcaa atatacagtt gcatcaatta cttctgctaa attatgtgga
     4141 ggtattgaag ttgccatacc aacagctata ccatttgagc catttactaa taaattagga
     4201 tatctagctg gcaatactga aggctctttt aacgactcat caaagtttgg tttaaagtct
     4261 acagtttcct tttcaatatc tctcagtagt tctaatgata atttactcat tttagcttct
     4321 gtataacgca tagcagctgg tgaatcccca tcaacagaac caaagttacc atgaccatct
     4381 actaaaagtg ctctagttga aaaatcttgt gccattctta ccatagcata ataaacagca
     4441 gtatctccat gaggatggta cttacctaaa acgtccccaa caatacgagc tgacttcctg
     4501 tatggtttat ctggagttaa atttaactca ctcattgaat ataatattct tctatgaact
     4561 ggctttaaac catctctaac atcaggaaga gcacgtccag ctataacact cattgaataa
     4621 tcaatatacg attttttcat ttcttccgct atttcaatag ggagtatttt gttattttct
     4681 tccatgtata ctaatcccct ctctctatat atctaagttt ctaacaaatc ttgcattttc
     4741 ttctataaat tcttttcttg gagcaacctt atcacccata agcattgaaa atacttcatc
     4801 tgcaattgca gcatcttcta cagtaacttg taataaagtt cttgtctcag gattcatagt
     4861 tgtttcccat aattgctctg cattcatctc tccaagacct ttgtaccttt gaagttcaac
     4921 accatttctt ccaatttcat ctaataagat atttaactct ttatctgagt aaacataatg
     4981 ttccttcttt tgctttgtca ctttatataa aggtggctgt gctgcataaa catacccctc
     5041 atctataaga ggtctcatat atctaaagaa gaatgttaat aataaagttc ttatatgggc
     5101 tccgtctaca tcagcatcgg tcataattat aattttatga tacctagcct tatctatatc
     5161 aaaatcttct ccaataccac aaccataagc tgttatcata ttttttattt catctgaaga
     5221 tagtatccta tctagtcttg atttctcaac attaagtatt ttccctctta atggaagtat
     5281 agcttgacta tttctatctc taccttgttt agctgaacct cccgctgaat ccccttcgac
     5341 taagaatatt tcacttttag atggatcttt ttctgcacaa tctgcaagtt ttccaggtaa
     5401 agatgtactt tctaatacac tttttctcct tgttaattct cttgcttttt ttgcagcttc
     5461 tctagctctt tgtgctctta aagctttatc aactatgatt cttgctgttg atgggttttc
     5521 ttctaggaaa gaccccagtt catcaactgt tacactatca actatacctc tcataaagct
     5581 attacctagc tttgttttag tttgaccttc aaattgaggt tctggtaatt taactgatac
     5641 tactgctgta agaccttctc ttatgtcttc accaagtagg ttaacatcat tttcctttaa
     5701 aaatttattt ctcttagcat aatcatttac agttttagta agagctgctt taaatccact
     5761 taaatgagaa ccaccttcat gtgtatttat attgtttgca aaagaatata tgttctctgt
     5821 ataaccatct gtatattgca tagctagttc aacaaaacaa tcatcaacct ttttatctat
     5881 ataaactatg tcatcatgta taccagttct agatttattt aaatacttaa tatattctac
     5941 caaaccacct gtatagtgaa attcttttct tttttcttgt ccttctcttt tatcttcaaa
     6001 tactattttt attcctttat tcaagaaaga aagttctcta agcctatact ccaatgtttc
     6061 atatttaaac tctatttcat caaatattgt ctcatctggc ataaattgaa tcattgttcc
     6121 tttatcttga gattctccaa ctacttcaag cttagatgtt ggcaatcctt tctcatatgt
     6181 ctgcttatat ctctttccgt ttaaataaac ctctgctacc atccattttg acaatgcatt
     6241 aactacagaa acaccaactc catgaagacc tccagatact ttatatcctc cgcctccaaa
     6301 ctttcctcct gcatgaagat tagttaatac tgtttctaaa gttgatttac cagttttagg
     6361 atgtatttca acaggtatac ctcttccgtt atcttttact aaaacactgc catcttcatt
     6421 aatagataca tatatgtctg aacaatatcc ttgtaaagcc tcatctatac tattatctac
     6481 aacttcataa actaagtgat gtaaacctct agggcttgta ctaccaatat acatacctgg
     6541 tctttttcta acggcttcta atccctctaa tacttgtatc tgacttgcac cgtattcttg
     6601 tttcatttaa tttcctccat tctctatgct aataacatcg ccattttcaa tattaaatat
     6661 tgtaacattt ttttcatcaa atattttttt atgtgaaact tcagcacttg ttataaacat
     6721 ttgaacattg cttaaattat ttactaaaag tttttgtctt gcttcatcta actcactaaa
     6781 aacatcatct aaaattaata ctggatattc ttcaacttca ttttttatta attctatctc
     6841 tgataacttt aatgatattg aagcagttct ttgttgacct tgtgaaccaa aaagtcttgc
     6901 atctaaatca tttatgaata tatttaagtc atctttgtgt ataccatatc tggtagtctt
     6961 agattctata tcattaggtc tattcgatga caacttggct aaaaatttat tatatactgt
     7021 atctatagta tcttcatcag ttatatttat ttgattttta tatcgaattg ataatctttc
     7081 aactccatta gtcaaattca tatgcatatt ttcagatata ttagctatct tttttataaa
     7141 gtctctacgc aaaatataaa tataacttcc atactttgct aacgtatcat catatacatc
     7201 taataaagct tcatcaacat gtatattttt aagcacccta ctcctttgag aaagtgtttt
     7261 attataattg gtaagatatt tataatattt aggtataatc tgactaatct ctttgtctat
     7321 aaatgccctt ctttctttag gaccctcttt aaccaacctt aaatcctcag gagaaaatat
     7381 aacaacattt aagttgccaa gtagttcttg tatcttttgt aaaggaactt tatttattct
     7441 tatccctttt ttatcttttc caataattag ctctattaga ctatatttat tatattttga
     7501 aaaacttcct ccaatatata agttttcact attaaatcta accatttctt tatctttgtt
     7561 agtcctaaat gattttccaa aagaaagcat ataaatagat tctactatat ttgtctttcc
     7621 ttgaccattt ttaccaacaa gtagatttac tttcccatta aattccagat gcaacttttt
     7681 ataatttcta aaattaacaa gttgcaaact tttaagtttc acaaaaagtt ctcctttttt
     7741 acaatacttt tattttagtt ccttctattt caactatatc tcctgatttt atcttttttc
     7801 ctcttcttaa ttctatttca tcatttactg tcactaaacc ttcttgaatt aaaaattttg
     7861 catgacctcc tgttgatgca atctctgcta atttaagaaa ttgatccaac tttatatatt
     7921 ctgattctat agttatttca gtcataatag ttcctccttg tcactatttt aaacaaattc
     7981 ctattgatac actaaaagta tattatacca taaatatgct tataaaagga gttgtctaag
     8041 attagaaaaa ttttctacaa aagacaactc cttcatgtct gctatatatt tgatgatatt
     8101 cttactggaa gcagtaagta aatataatta acatcatctg ttggtttaat tatacaagga
     8161 tttacatttg tagtaaattc tataaatatt tcctcattat ctatattttt caaaccttcg
     8221 ataaaatatc tagaattgaa agctatatct aggtaatctc catctaaatc tatttcaact
     8281 tcttcataca catttccttt ttctgtatta gaagtaattg ccattacttt atctcttata
     8341 gataacttta taagattatt tttttctgat tgagacaata aagacgctct ctctatacta
     8401 tttaaaagtt ccttagtatt taatttaact ctgctgttat gttctcttgg caataatttt
     8461 ttataatcaa taaaatctcc ttcaagcaat cttgtaataa ttttcgtatc attaattata
     8521 aaaatagcat ttttttcgtt aaatccaact ttaacattat cctctccaga aagcaaacta
     8581 tttacatcta taagtgtctt tccaggaatt atgactttta tattttcagt taaactatca
     8641 accgaacaac tttttacagc taatctatat ccatcaattg ctactaaatt taagtttcta
     8701 tctacaattt ctaaaagttc tcccattaaa acaggttttg tttggtcctg tgagatagca
     8761 aatacagttt gtttaatcat attttttagg atttcttgag gtatgctata taaatcttct
     8821 tcatttaatt ctggtaattt aggaaattct tttgctgcat aacctttaat tttaaatctt
     8881 gaatttacac aatttatgta aatattattt tctgaatcag tttctatctc aacaaaggaa
     8941 tctggtaatt ttctaattat atctccaaat agccttgcat ctacaacaac atcacctttt
     9001 tctatgattt ctgcttgtac ataagtttct attcctattt cagcatcata tccagtaagt
     9061 tttaattgac cttcttctgt agatataagt atacctttta ataattctat tgttgttttt
     9121 ccattaatag ctttttgagc aattccaatt ctatttgcta ggattttttg attacaaatt
     9181 attttcaatg tggataacct cctctggctt tttatatata aaaataagtt aaaatcatag
     9241 tagtaatagt agtaggtgtt gttgataatg ttaataagta tgtataacat tataaataca
     9301 aagatattaa catgtgtata agatgttaat atctttgtta ttttagactt gataatttgt
     9361 taataatttt tgttcaaaaa aagtattaac aggttattca agagatataa acatacaatt
     9421 gtgtataaat tatcccttca aatctgatat aattttgtct attttagtct taatttcttc
     9481 actttcttct atatccttag atactttgtc atgagcatga attactgttg tatggtctct
     9541 acccccaaac tcttcaccta ttttaggaag ggataaatca gtaagctcgc gcgttaaata
     9601 catagctatc tgtcttggat aagctattga acgtgttctt tttttagaat taaaatcttc
     9661 catctttaaa ttgaatacag aagatacttt ttcttttatt ctgagaacat ttatttcttc
     9721 atttttagaa gttgttataa tatcttttaa agcttctgta gcaagatcaa aagatattac
     9781 cctattgcta agagaagaat aagcaaccac tctagttaat gcaccttcta gttcccttat
     9841 gtttgactta atattttttg ctatatatga cataacctca tttggcacat ctatacgttc
     9901 tagttgagcc ttttttctaa gtatagcaat tcttgtctca aagtcaggtg cttgaatatc
     9961 agttataagt cccatttcaa atctcgatct tagcctatct tctagtgtag gtatgtcttt
    10021 tggcggtcta tcactagata taattatttg tttgtttgct tcatgaagag tattgaatgt
    10081 atggaaaaac tcttcttgag ttctttcttt tcctgctata aattgaatat cgtcgattag
    10141 taatacatct acgtttctat atttattcct aaattcttcg tttttatcgt cttttataga
    10201 gtttataagt tcattagtaa atttttctga agaaacgtaa actacttttg agtctttttt
    10261 ttgactaaca atatgatgac ctatagcatg cattaggtga gtcttaccta atccaactcc
    10321 tccatacaaa aaaagtgggt tataagcttt agctggagat tctgcaactg caacgcatgc
    10381 agcatgtgca aatctattac tattaccaat aacgaatgta tcaaatgtgt attttggatt
    10441 tagattgggg taaagaactc tataatttaa atctgtgcta tcagaattta aatcagcaac
    10501 ctctttttcg ctcaatacaa atttaatatt atattttttt aatgacagtt gactaatagc
    10561 atcttcaatt aaatgtaaat atctattctc taagatatct ttattaaaat cactaggagc
    10621 cagtaagatt aaatcattaa gatgtatttt taatggtacg atgtttttaa aaaaggtatt
    10681 aaaacttact gaagttaagt caccttttat taattgtagg gttttgtccc ataaagaaac
    10741 tatatccata atataaacct ccgaacagaa taattaatat tttccacaaa gttattaaca
    10801 gaaaagcaaa aatatatata aattttacag aataactaaa tttatggata atggtgttga
    10861 taaattaata atagtataaa ttattaaaaa aatatgaaaa gatataaaca atatgtagat
    10921 aaagttataa ataacataaa catacaataa atggtgatta taactagagt attgtcagta
    10981 atcttaaaag ttatacacaa aagtatccac aagctgtgaa taatttctaa taagttgata
    11041 acatttatgc acattatcaa caagtatatt tataatatca aaatatatgt caaacttcaa
    11101 tgatttgtaa ctaatttatc cacaatatta actaattgtt gataaaaata taaacatgtt
    11161 aaaattactt tatttgtgta tataattgaa aaaaataatt tagaataaaa ttaaatagat
    11221 ttttactagt attttcaata aaaaaaatac ataatatata tatggtagat tttgtgatat
    11281 aagcgtccca aaaactcgtt gacaacagta gtaaaagtat ttataattat atgtgttatg
    11341 tttactttga gggtaaagtt attattttta taaacggaaa ataaaatctg aaaggcggtg
    11401 caaaataatg agtaaaagaa cttatcaacc aaaaaagaga caaagaagta aagaacatgg
    11461 tttcagaaaa agaatgaaga cgtctaacgg aagaaacgtg ttaaagagaa gaagagctaa
    11521 aggaagaaat agattaactc attaattaca aaagggccgc tgcaaaggtg gcctttttgt
    11581 gtaaataatt acaattcata gctgtgttta tggaggttaa ctatggactt taataggact
    11641 aaagggttga aaaaagactc tgattttaga aaagtatata aacacggcaa atcttttgca
    11701 aacaaatatt tagtaatata tatacttaaa aataaatcag attatagtag agtaggtatt
    11761 tctgtttcaa aaaaagtagg aaaagctatt actaggaata gagtaagaag attaataaaa
    11821 gaagcctaca gattaaatat tgatgaaaaa attaagcctg gatatgatat agtatttata
    11881 gcaagggtat ctagtaagga tgctactttt aaagacatag acaagtctat aaaaaattta
    11941 gttaaaagaa cggatatttc tatttaattg tatgctataa atatggaggt taatgacttt
    12001 gaataaaata atttatatat taaaggaaat aagtaagcat ttatcgaatt tatgtattta
    12061 tttagtgaga ttttatcaaa agtatatatc tcccttaaag ggacctacct gtagatttta
    12121 tccaacttgc tcacaatatt caatagaggc gtttaagaaa tatggatttg taaaaggtat
    12181 gtatttaacg ataagaagac ttttaaaatg tcatcctttt catccaggag gttacgaccc
    12241 tctaaaataa aagagagtaa ctattaggag gtataaaaaa attgaatata ataggaaatt
    12301 tcttaggatt gattcttaag gtaatatttg aatttgttaa tcattatggt atttctataa
    12361 tactttttac gatacttgta aagattattt tattaccatt aacaattaag cagactaagt
    12421 caacaaaggc aatgcaagat atacaacctc gtataaaaga gatacaagaa aaatataaaa
    12481 ataagccaga aaaacaaaat gaagaaattg ttaagttata tggagaagct aaaattaatc
    12541 cactatctgg ttgtttacct ttattaatac agtttcctat attaatagga ttatttagcg
    12601 ttttgagaga accagttgct catggcgttt ttgcaaacaa agctgcattt ttagcagctg
    12661 acaatgggtt tttatggata aaaagcttaa catcaccaga ttatgtatta gcagtatttt
    12721 caggagcaag tgcatatgtc atgcaaaaag taatgacacc aaaagatcag ttacaaggct
    12781 ctatgaaagt aatgacatat gtaatggcag gtatgtcttt ctattgggga tttatattcc
    12841 cagcaggact tacattgtac tggacagtaa gtaacttatt ctcaatagct caatattact
    12901 taataatgaa tcctttaaaa gctaaactgg ctgctaactc taaggaggaa aaagttaatg
    12961 agaaaaagcc taaaattaat aaaaagtaag agtaaagagg aagctataag taaagctata
    13021 gcagagttga atttaaaagc agaggatata gaagtagaaa tacttgaaaa tccaagtaaa
    13081 gggtttttag gttttatagg tgctaaagat ggtacttatg aaatttttgt tatcgagagg
    13141 gaagtagatg tagctaaaaa ttttatagag gtaatgttga aaaatgcaaa tgttgatgcc
    13201 aaagtcaatg tatctcaaaa agataattta atcatggttg atattgaagg caaagaagct
    13261 gcaagtttaa ttggtagaag aggggaaact ttagattcta ttcaattttt gactggatta
    13321 gctcttaata aaataaataa agattctcat acaagagtac ttgtagatat agaaaattat
    13381 agatcaaaac gagaagaatc tttaataaga tatgctaata aagttgctag agaagtagcg
    13441 aaaacaagaa aaactaaaaa attagattat atgaatccat atgagagaag aataatacat
    13501 tcagctcttc aaaatgacaa atatgtaatt acatatagtg aaggaaccga tccatataga
    13561 agattagtaa ttgagtgtaa aagataaagt caacctccta aacattaggg ggttttattt
    13621 tttaatatta ttaaatcatt aatggttggt taaatgtaaa tctatatgta aaaaattatg
    13681 aattaagagg tgataaattt gtttatagat gatacaattg cagcaatagc tacagcacct
    13741 ggagaaggtg gtataggtat acttagaata agtggagaaa aagctttgaa ggttgcagaa
    13801 gaaatcttta aatctatgtc tggaaagagt attgaagaat acaataagag aacattaata
    13861 tatggaaata tagtggataa tgaaaatgta attgatgaag ttttattggc atatatgaaa
    13921 ggaccaaatt cctatacagg agaagatgtt atagaaatta attgccatgg tggatttatt
    13981 tcggtaaaga agatattaga attaatacta tcaaaagatg ttagattagc agaggctggt
    14041 gagtttacta aaagagcatt cttaaatgga agaatagatt tatctcaagc agaggctgta
    14101 attgatgtta taaaagccaa aactgatata gctcatgaag ttgctcaaaa tcaattagag
    14161 ggttctttat caaagaagat aagagaattg agagataaag tcactgagat attagctcat
    14221 gtagaagttg ctatagatta tcctgaggaa gatattgagc atataacata tcaaactctt
    14281 aaagaaaaaa ctgatgaact taaaaaagac attaaaaaat tatatgatac agctgaaagt
    14341 ggaaaaatac ttagagaagg cttaaagacg gtaattgttg ggaaaccaaa tgtaggtaaa
    14401 tcttcactac ttaattctat tttaggagag aatagagcaa tagttactga tataccagga
    14461 actactagag atgttataga agagtttgta aacataaaag gtataccttt aaaaattgtt
    14521 gacacagcag gtataagaga tactgatgat attgttgaaa aaataggtgt tgaaaagtct
    14581 aaagaatcat ttactagtgc agatttgata gtaatggttt tagatgcatc tagaaagttg
    14641 tcagaagaag atatagagat attagaaaaa cttaaggata aacaaacaat agtgctgtta
    14701 aataagaatg atttgaaaca agagattgaa gaagaaaaaa tacttaaata tgtagaaaat
    14761 aatagtataa taaaaatatc agctttacaa caagaaggaa tagaagaatt gcaagataaa
    14821 atagagtcta tggtatataa aggtagtatc aaaaataatt ctagtttagt agtaacaaat
    14881 tcaagacata aagatgcact tagtaaagca tataaatctg caacagatgc tttaattgct
    14941 ttggaacaaa gtatgccatt tgactttgta gaagtcgatt taaaaaatat atgggactat
    15001 cttggatata ttaatggtga tacagtaaca gaggatttac tagataatat attccataat
    15061 ttctgtattg gtaagtaatg tacaaaagta aacttgtttt tattatagag atttttaaaa
    15121 aatttgaagt gtttctcatg aaacattaat tttgaaaaga aaggaattat aaatgataaa
    15181 gtttgaagca ggaaaatatg atgttatagt agtcggagca ggacatgctg gatgtgaagc
    15241 tgctttggct actgcaagaa tgggatataa aactttgata ataacaatgt ctttggattc
    15301 catagcatta atgccttgta atccatcaat tggagggact ggtaaaggtc aattagttaa
    15361 agaaatagat gccttaggcg gtcagatggg attaaatata gacaagacat atatacaaag
    15421 tagaatgtta aatactgcca aaggtccagc ggtacactct ttaagagcac aagcagataa
    15481 atttaaatat catgaagaaa tgaaaaagac attagaagat gaaccaaatc ttgatatagc
    15541 tatggatgaa gttgtagaaa tacttcatga aggaaatgtt gtaataggag ttggaactaa
    15601 actaggatgt tcatttaaat ctaaagctgt aatattggcc actggagttt atctgaactc
    15661 aaagatatat atgggtgaag ttgcatttta tgaaggtcct aatgcattag ggtatgcaaa
    15721 atatcttaca gatagcttag ttgagcttgg ccttagaatg agaagattta agacgggaac
    15781 tccagcaaga gttcatagag atagtataga cttctctgta atgtctttac aagagggtga
    15841 tgaaaaagta actccattct catttatgaa tgaaaatata gaaaaaaaac aagaaccttg
    15901 ttatttaaca agaactacag aagaaactca aaaagttata ctggataatt taaaaaggtc
    15961 tgctatgtat agtggagtaa tagaaagtac tggtccaaga tactgtcctt ctatagaaga
    16021 taaagtagta agatttagtg ataaaacatc acatcaatta tttatagaac cagaagggtt
    16081 aaatactaaa gaaatgtata tacaaggaat ttcaactagt ttaccttttg aagttcaatt
    16141 agatatgtac aaaactataa aaggacttga aaattgtaag ataatgagac ctgcatatgc
    16201 tattgaatat gattgtgttg acccaactca actaaaaata agtttggaaa taaagggtgt
    16261 tgagaactta tttagtgcag ggcaatttaa tggaacttct ggatacgagg aagcagcagc
    16321 tcaagggctt atggctggta taaatgcagt tagaaagata gaaggaaaag agccatttgt
    16381 attagaccgt tcagaagctt atataggtgt cttattagat gaccttgtta ctaaaggaac
    16441 taacgagcct tacagaatga tgacatcaag agcagaatat cgactatatt taagacaaga
    16501 taatgcagat atgagattaa ctcaaaaagg ttatgatata ggattagtta aaaaagatag
    16561 atatgaaagg ttcctaaata aaaaggctgc tgtagagaaa gaatttgaaa gactaaaaaa
    16621 tgaaagagtt acaccaaaag aagtaaatag tttgttggaa gaaaaaggag caacaccaat
    16681 aaaggttgga atatctctat atgaattttt aaagagacca gaggttactt acgaattgct
    16741 tgaagaatta gggaaaggcg ctggagaaga tgtttcaaga gaagttaaag aacagtgtgt
    16801 aataataact aaatatgaag gttatataga gaaacaattg aaacaaatag accaatttaa
    16861 aaaacttgag aataaaaagt tggatgagaa aataaattat tcatctatag aaggtcttag
    16921 attagaagct agacagaaat tagatgatat aaaacctatt tcaatagggc aagcatctcg
    16981 tatatctggt gtttctccag ctgatatatc agttttactt atatacctag aacaaatcag
    17041 aagaactaga ggtggcaaag gtgaataata tagaacttct gaaaaacggg attgaaggtt
    17101 ttaatataga tacgaatgac agtatgttag aaaaatttaa aatctataga gagatattag
    17161 ttgaatggaa taaaaagatg aatcttactg gaatagaaga tgaaaaagaa gtgtatataa
    17221 aacatttttt agactctatt tcagctgtaa aaaatggata tataaaaaat gggatgtcta
    17281 taatagatgt tggtacaggt gctggttttc ctggaatacc attgaaaata tgtttagata
    17341 gcttagaact tactttgtta gattcgttaa ataaaagaat aaacttttta gaggaagtta
    17401 gtagagtact agagttagat aatattacat ttatacatgg aagagctgaa gattttggta
    17461 aaaatgaaga ctatagggaa aaatatgatg ttgctacggc aagagctgtt gctggattac
    17521 cgattcttat ggaattttgt gtaccatttg taaaagttgg agggtatttt atttgcttaa
    17581 aaggtccgaa tgctaattta gagctagaag aatcacaaaa ggctattgat gttttaggat
    17641 tggagtatat tgaaaaaata gatgtagagt taccagaggt agatttaaat cataatatat
    17701 tagtttttaa aaaagtgatg gaaacaccag ttaagtaccc tagaaaagct ggtaaaccag
    17761 ccaaaaatcc tattaagtaa tgaaaaattt attattggta agcttaatta tttctcagga
    17821 aataattaag cttactgtaa aaaaacaaaa ataaaggaat tattaaagta gatgcagaaa
    17881 taaatttgta tgtacatata gagaacaaaa ataatttata tctaaaataa gagaggtatg
    17941 ttatggaaga taaaagagtt atggagatac ctatagaaga tgtagttcca aatccatatc
    18001 aaccaagaaa aatattttca caagtttcat tggaggaatt gagcaattct ataaaggtat
    18061 atggtataat tcaacctata acagttagag caaaagatgg caaatatgaa ctaattgcag
    18121 gagaaagaag attaagagca gctaaattag cagagcttaa aaccatacca gcaattataa
    18181 ataatatgaa cgatgaatct tctgctgttc tagcgttatt agaaaatttg caacgagaag
    18241 acttaaattt cattgaagaa gcaattggtt atgaaaactt aataaaagaa catgctttta
    18301 ctcaacagca attagcagaa aaattgggca aaaatcaatc tactgtagca aataagctta
    18361 gaatattaaa gcttccaaac gatataaaaa tgaagctaat agagaataat ttaacagaaa
    18421 gacatgctag agcatttctt aaactaccaa gtgaagattt aatgcaaagt gtgttagaca
    18481 aagtcataaa aaatgaattg actgttaaaa aaacagaaaa attgatacaa gatgtattag
    18541 aagaaactaa agttcaagaa gagcctgata aaaaacagaa tataaagggt gctatgagta
    18601 taagaattta cataaatact ataaagcagg cctttgatgc tatatcaaat acaggaattg
    18661 atgctaagta taatgaaata gataagggag attatatgga agttgttgta aaaatcccta
    18721 aaaaatagag attactgctt accagtaatc tttttttgta atataagcct tgtaatataa
    18781 attgatttat agacattatt tatacttaaa aaacacctat tcaacattta aaattaattt
    18841 aattcttaaa ggggggaaca tcatgggcaa agttatagct gtattcaatc aaaagggtgg
    18901 agtcgggaaa actacaacaa atgtaaattt aagtgctagc ttaggaactt tgggaaagaa
    18961 aatattagta ttagatttag acccacaagg aaatacaact agtggatatg gtattaataa
    19021 aaacgaagta gaaaatacaa tctatgaaat tatgttagat gggttacata ttaaagaagc
    19081 aataataagt actgaatttg agaatgtaga tgtagttcca tcagctactg aactatcagg
    19141 tgcagagata gagcttacat ctaaaactaa tagagagtat attttaaaaa attccataaa
    19201 agcggtaata gatgaatatg attatatatt tttagattgt ccaccctcac tggggatgct
    19261 tacaataaat tgtttaactg ctgtagatag tgttttaatt ccaatacaat gtgaatatta
    19321 tgctttagaa ggtgttagtc aattaatgga gactataaaa ttagtaaaat caagattaaa
    19381 tgctgatata gaaattcaag gtgttgtttt aagtatgttt gatggaagag ctaatttatc
    19441 aatacaagta gttgaagaag ttaagaaata ctttaaaggt agtgtatata caactttaat
    19501 tccaagaaat gtaagacttg cagaagctcc aagtcatgga aaacctgtaa tttattatga
    19561 taaaagatgt agagggtctg tagcttattt ggaactagca gaagaattta tagatttaga
    19621 agaggaggaa tggtagtatg gagaataagt ctaaaagaag taatagatta ggtagaggtc
    19681 ttagtgcatt gataccagaa attaaaggag aaacttcaga aaaagaaata gtcaacatag
    19741 atatagacaa aatatatcca aacgaagttc aacctagaaa gcaatttgat gaagaaaaga
    19801 taaaagtatt gtcggattct ataaaaaatt atggtgtttt acagccaata gtggttaaaa
    19861 tggatgaaaa taataaatat atgataatag ctggagaaag aagatttaga gcatcaaaac
    19921 ttgcaaataa aaatcaaata cctgctataa ttaaagatat agatatgaaa gatataatgg
    19981 agatagcctt aattgaaaac ttacagaggg aagatttaaa ttcaatagaa gaggctctag
    20041 catataagag tttaatagag cattacaatg taactcagga agaaatatca gaagctgttg
    20101 ggaagagtag acctcatata actaatacac taagactttt aaatcttgga caagatgtta
    20161 tagaaatgat agacagtggt agaattacag caggccatgg taaggcttta ttgagaattg
    20221 cagataaaga tttgcaactt caaatagcga aaaaaataga agaagaagaa ctttctgtaa
    20281 gagaagtcga aaatatagct aaaaaaatat ctgaaaataa acaagaagaa cctaaaaaat
    20341 ctaaacctaa ggatgtattt attttagatg ttgaagataa acttagaaat atatttggaa
    20401 caaaggtgaa tatttctaaa ggaaagaaaa aaggtaaaat agagatagaa tactataatg
    20461 atgatgattt aaatagtatt gtatcaatgc ttcttgaata gaacaaaaat ataaaacaga
    20521 gaggaagatt gttatgattt atttagataa tgctgcaact acatatccaa aaccagaaag
    20581 agtgtataat gctgttttag attgtatgaa aaattattgt gcaaatccag gtagagcagg
    20641 ccataaactt gctatgagag ctgctaggga gatatatgat acaagagaga atatagctaa
    20701 gttgttcaat gtaagtaatc ctatgaatat agtatttaca tctaatgcaa cagattcttt
    20761 aaatttagcg ataaaaggtg tattacaaga aggagaccat gtaataacaa cgtctatgga
    20821 gcataattca gtaataagac ctataaaagc attggaaaaa aggggtattg aaaatactgt
    20881 agtaaaatgc gattatgagg gatttttaga ttatgaagat ttagaaaaat caataaagaa
    20941 taatactaaa ttgattgtaa caacacatgc gtctaatgta tgtggaactt taatagatat
    21001 aaaaaaagtt ggagaaatag ctaaaaaaca taatatacta tttttagtag atgcatcaca
    21061 aacagcaggt gtttatgata tagacgtaaa tgaatgtaat atagatatgt tggcaatgcc
    21121 aggtcataaa tgcttatttg gacctcaagg aacaggtata ttatatgtaa gagaagggtt
    21181 gaacttaaat atattaaaag aaggtggaac aggtagtaaa tcagaagaaa tagttcaacc
    21241 agagttattc ccagataaat atgaatcagg aactcataat actccaggta tagcaggtct
    21301 taaccaaggt atactattta tatttgaaag aggaatcaac aatataagac aacatgaaga
    21361 agaattatgt caatatatga tagacaaatt agaggaagta ccagatataa agatatatgg
    21421 accaaaggac agtaaaaaaa gagcatcagt aatagctcta aatataggag atatggattc
    21481 tggagaggtt actttcttat tagatagtga ttataatata gcgactagat caggaataca
    21541 ttgttcacca ctagcacata ccactttagg tactttaaaa caaggtgcag taaggttcag
    21601 tataggatat ttcaacacaa aagatgagat agataaagca gtggaagctt tgaaaaaaat
    21661 ttcaaaaaat aaatagcatg agatttaata atatagaaat aaaaaaaggg gatatttcaa
    21721 aataaaaatt tgaatcatct ccttttttgt acaaaaaaga aaaggggttc ctaagaacct
    21781 ctaatctatt tgataatagt ttcaagaaat tactttaagt aatctccttc ttcaagaact
    21841 atatgaccac tttcgtaatt agaaccatca acagtaattt ttatttgttc aacattcata
    21901 ttttttatgt aagtacgagc aactgaatca agcattaaag tttctgcatc actacctaag
    21961 tttgactttg taaagtcaga gctaacatct aatataccag tttttacacc atcaatgtct
    22021 tttgtagtaa atgaatttaa ttttgcagat tctggaacaa ctttaagttt ttgaagttct
    22081 tcaaataaag tgttctcatc aattttattt aaatcaactt tattttcaat taaatctgtc
    22141 ttatctacat caaaagagta aatagtagct gattgagctt tagtttcttc ttttggagta
    22201 ggtttagctt tgttattagg aacctctttt tcagtattgt tttcttcttt tggttgctca
    22261 acatttgtat tgctcttagt ttctttttta gatgaatcac ttccattttg agcattagta
    22321 caaccaactg cgaatataga tatagataat atacttaaca ctaacattat tttcttattt
    22381 ttcataaaaa tttctcctct cttaaaaact attcttatat ataattatag tcgttatgag
    22441 caaatatatg aatacaaaat agtaacaaat ttaaaaaatg atttatttaa attaataaaa
    22501 ctcaaaataa actaaatttt agtcattttt atgggaaatc atttaatgta cagtgaaaat
    22561 attgtaaaat aaaagtagtg tttttaaaat aaatataagt tataattata ttataaaaaa
    22621 atgtcttcaa aaggtgggaa tagtatggaa attttgagct taggagaaaa gattaaaaag
    22681 ttaagaaaag aaaaaaacat gacattgaaa gaattagctg gagataggat aacagcagca
    22741 caaataagcc atatagagag agataaatct catactagtt atgaactgtt ggaatatcta
    22801 ggcgataagc tagatgtaag tgtagaatac ttattagaga ccaaggaaat gcaatcaaaa
    22861 aagataactg ataatttaat actacagagc gaaatttata taaaagaaaa tgaattaaac
    22921 aaggctgagg accaaataaa agaagtttta gatatatgta agagatacga tttaatggag
    22981 aactatggca gatgtaattt tttaatggct aatattaatt tgaaaaaatc taattataat
    23041 gatgctatag aaaactttga aaaggcattg tacttcttta taaaaaatag tgatagtgaa
    23101 aatatactta agtgttattt aaacataggg aaaatatata tgcaggaaga cttttataaa
    23161 ggtgctataa gccactttaa ttttgcagag gaaattttgt cagagagtaa atttgaggat
    23221 gttaacatac acaaggaact atatagtaag atggcatatt gttacataaa actagataat
    23281 ccaaatatgt cattgaagta catagaaaag ataaatgaaa tagataatag aaatgataga
    23341 aaagaagatg tcgatatttt ggtgttaaaa gcaaataata tgcttgagat tggaaaatat
    23401 gaagaatcaa gagattactt taaaaaagca ctaaaaatac ttgagagtga ggataataaa
    23461 actggattag caaatgtgta tttaacaatt tgtgatgttt acagaaaaat aggtgaaaca
    23521 gatagagtac ttgaatattc acaaaaggta tatgacataa agaaaaatga tgaagatgaa
    23581 tacatgatgt caggattatt taagataata gaagcatata tagataaaga agattatgat
    23641 ttagctagaa aatattgtaa gatagcctta gcttcatcaa taaaaaataa aaataaattc
    23701 aatgaatata aagcattgag attctatgct aatatgtata aaaatcagaa tgaagtaact
    23761 cttgcaattg aatatctgat taaatgcata aaaatagtat cagatttagg caacaataga
    23821 atattggcca atttatatat agacttaggt caattatatt caaatatatc aaaagaaaaa
    23881 gagttagaat attatcaaaa aggtgtattt atgtacaaaa atttagaaat aatgtagggt
    23941 aaataaacct ataagggtat agaaacaatc tataacaagc aagataatat ctatgataaa
    24001 atataaattg tatgaatatt tttaaggaga tgaatcagac aatgagtata aaaatagatg
    24061 cgagagggct tgcttgtcct aaaccagtta taaatacaaa aagagaattg gataacctag
    24121 aagaaggtgt tgtagttaca atagttgata atgaaacagc taaggagaat atattaaaac
    24181 ttgctaaatc tttaagttgt gaagcaaata ttgttgacga aaaagagaat tttatatcta
    24241 tagaaattag aaaaggtaaa aatatactag ataaacaaaa tgttgtagat aataaagaaa
    24301 gtgaattaga caatacatgt atatttatat cttcagataa gatgggactt ggaaatgacg
    24361 aattaggaaa agtgttaata aaaggattta tatatacatt aacagaatct aaaccttatc
    24421 ctaagtatgt acttttagtt aatggaggag taaaattaag tgctgaaaat gaagaaacca
    24481 tagaaaatct aaaaatactt gagaatatgg gtgtagaagt tttatcttgt ggtacttgtt
    24541 tagattatta taatttaaaa gacaaattac aagtaggtac agttacaaat atgtatacta
    24601 tagttgagac attaaagaat gcatcaaata ccatttctat ataatgtatg tatgtttaat
    24661 aatataaaac taacaataaa gattaactca aatagatagt cagaaaggat taagtaatga
    24721 atcaaatgta tatagtgtca tttaattcga cacatcatgc gataagatca gaaaagttat
    24781 ttggtgaaaa tagtctaaaa gtaatggctc ttccaacacc aagagaaata acagcaagtt
    24841 gtggaatatc aattaaattt tcttttgaag atatggaaaa gataaaaact attttggttg
    24901 aaaataatgt agatataaaa ggaatttatt gtataagtaa attagaaaat ggttcaaaag
    24961 aagtagagaa gttagattag gaggctaatt atttatgcca atggatttaa aaataggtga
    25021 tattgttgaa ttaaaaaagc aacatgcatg tgggtgtaaa gagtttgaaa tcataagaac
    25081 gggaatggat ataaagataa aatgtactaa atgttcaagg ctaataatgc ttgatagaga
    25141 gaccttagaa aagagagtaa aaaagctaat aaaaaagtga taaaaattta acacttaaaa
    25201 aatgtcaaat accgtatatt aatatccaaa attttggtat aataagaatt gaagaaaaca
    25261 ttttcatggg ggtgctttaa ttatggcagt taaatatgca aaaagaatgc aaggattaca
    25321 aggatcagaa atacgtgagc ttttaaaact tactcaacaa ccacaaataa tatcttttgc
    25381 tggtggaatg ccggctccag agttatttcc agttgaggaa atgaaaaaag tatcagttgc
    25441 agtgcttgaa gaaaatggaa gatcagctat gcaatatact acaacagaag gatatgaacc
    25501 attaagagaa aaaatagcag ctagaatgaa tgataaaaac aaaactaatg taaacaaaga
    25561 tgatatatta gttacaagtg gttctcaaca aggtctagat tttgcaggaa aagtatttat
    25621 tgatgagggt gatgtaattt tatgtgaaag tccatcttac ataggagcta taaacgcatt
    25681 taaatcttat caacctaaat tcatagatgt tccaacagat tctgatggaa tgataatgga
    25741 agaattagaa aagatactag aaacaactga tagaataaaa atgatttatg taatacctga
    25801 cttccaaaat ccaacaggaa gaacttggcc acttgaaaga cgtaaaaaat tcatggaaat
    25861 agtaaataaa tttgaaatac cagtaataga agataatcca tatggagatt taagatttga
    25921 aggagagact ttaccatctt taaaatcaat ggatacaaaa ggattagtaa tattcttagg
    25981 aactttctct aaaatattct gcccaggata cagattagga tggacttgtg cttctccaga
    26041 aattttatct aagtttaact ttgcaaaaca aggtgcagac ttacaagcat caactatatc
    26101 tcaaatggaa gtaagcaaat ttatggatat gtatgaccta gatgcacatg ttgacaaaat
    26161 aaaagcagtt tatgttaaac gtagagatgt aatgcttaag actatggaag aagagttccc
    26221 agaaggatta gtatttactc atccagaagg tggattattt acatgggtag agcttccaag
    26281 taatttaaat gctaaagaat taatgccaaa atgtttagat aagaatgttg cttatgttgc
    26341 tggaggagga ttcttcccta atggtggtag agaaaatact ttcagactta actattcaaa
    26401 tatgccagaa gaaaaaataa tagaaggtat aaaaaatata gcagctgtat taaaagaagc
    26461 tatgggtgta gaagcttaat taaaaataat aacttatata taatacaagg gatggttgtt
    26521 gccatccctt gtttgtttga aaagtatata attcacctta tactaaactt tgtccaaaat
    26581 ttaaattgac agaaataaga ataaatgata aaatgtgtag gtatgagatt ttagtctcat
    26641 ttctctgctc taagagtgta gagccgttaa gtccaaaggg aggtgaatta tagtgagaaa
    26701 ttatgaatta gtttatgtgg taaagccaaa ctctgatgaa gaagtaagag aggctatact
    26761 aaacaaagtt aaggaagttg ttgcaactga cggagaaata gttaaagttg atacttgggg
    26821 aactaaaaaa ttagcttatc caatagctaa gtttacagaa ggtttctatg tattagttaa
    26881 cttcaaatca gcagtagacg ttcctaaaga gatagacaga aacttaaaga taaatgaaaa
    26941 cgtaataaga cacatgatag ttgttgctta ataactggtt ttattataaa aaataggtgg
    27001 tgtttttatg aatcaagttg tattagtggg aaggttgact agagaccctg aattaagata
    27061 catcccaggt acaggaacac cagtggcatc ctttacaata gccattgata gagactatgt
    27121 aaaaaaagat ggatctaaag aaactgattt tatacctgtt gaagtaatgg gtaaatctgc
    27181 tgaattttgt gctaactaca taactaaagg tagattagta gcacttcaag gatctataag
    27241 agtagacaat tatcagacac aatcaggtga aaagagaact tttacaaaag taagtactag
    27301 atcagtacaa gctttggata gtaagaataa atcggaaaat tcatatagag agagtgctcc
    27361 agcttttgag ccaagctttg aacctcaagg tttagaccca caaggtttcc aagctataga
    27421 tgatgacgat ataccatttt aaaaaggagg gaaaaaagtc atgatgaata aaaaaagacg
    27481 taagaaaaaa agagtttgtc aattttgtgc tgacaaaaac gctaaaatag attacaaaag
    27541 tactcaaaga ttacaaaagt atataactga aagaggaaag atattaccaa gaagaatatc
    27601 tggaacttgt gctaagcatc aaagagaatt aacagttgct ataaaaagag cgagaaatat
    27661 agcactttta ccatatacat tagactaaaa aaatgagcct tgtgctcatt ttttattata
    27721 tgtatttata tatctaaatg aggcgagcta taaagctcgt ttttttgttt atatacttaa
    27781 atatattatt atttatgata taatattata tattaaggag ggttgtaaac gtgaaaatag
    27841 ataaaggttc tgagataacg agaaacataa agataataga atggatgaaa acagaaatat
    27901 taatgagtgt aagtgatttg tttaatttat tgtttaaagg ggtaaaacca ttagatgaag
    27961 caattcaaga tactttagca aatataataa tgataacata tctcttagca aagagattag
    28021 gaattagttt tagagatgtg gattataaag tcaaggaaaa aataaaaatt ggtatagatg
    28081 aggaccatag cgttgaaaga tggtatggag atttatctaa tttaaaaaaa catatggata
    28141 atagggagtg atattaaatt gaataataaa attagactat ctaaggcaat gtctataata
    28201 gttttagcta taataatcgc tttagtaata gcctatattc caatgctagg aatatttagt
    28261 atgttagcag ctgttccata tgtaattata ggtgctatta ctgatagaaa gtattctctt
    28321 atatctattt tggttacatt ttgtgtactg attctatttg cagacatttc ttatgcatta
    28381 aatatatgta taatgtattc tttaccaggt atagtaatag gaaagatgct aaagagaagc
    28441 tttgaacaag aggacagtaa taaattcgaa ccgatatatg gtggaaccat aatatttgta
    28501 ctttcaatgc ttgtatattt ttttgtatta aagacatttt taaatgtgaa tctattagat
    28561 gaagtttcta agatgatatc agaaattgta aatattcaaa aaaatagttt ttctgcaact
    28621 gaacttaaag tgtttgataa aatgaagcca gatgagattg taagttattt tacaaatatg
    28681 ctaccaatga tgttattttt acaagggttg ttatcagcgt ttgtcacata ttatttgagt
    28741 gtatttttta taaaaaggat tacaaagatg aatataagat ttcctaagtt tgctgatttt
    28801 tatttaccgg gaaatgctat actcacaact ttcttacttt atttattagt cttatttatt
    28861 caaattattg gttcaaaatt atatacagaa ttaataatga ctaatttaca gctagttttt
    28921 aatttaatgt ttgtaattca aggtatagca gtttgcattt atttcttaaa gaaatggata
    28981 agacagggac caaataaaat tatgtttttt tcagggataa ttttatgttt atttggattt
    29041 atgggaatat cttttgttgg tatggtagat agtataattg actttagaaa ggtaagaagc
    29101 tataaatcca cttaggagga tagaaatgag taataaacaa acctttaaat taaatatgcc
    29161 agaaataaat ttatatataa ttgttattgg tatttctagt ataattttgc tttattacaa
    29221 cttgtatgta gggtgtttat ttttctgtat ttttgtatat atggtttttc acaattggag
    29281 aactactaat attagacgtc atgaatggac agagtatatt caaaatttat ctttagatat
    29341 agatgaaaca actaaaaaag ccataataaa tcttccaata ccattatgta ttttagaatt
    29401 tgatggaaat atatcctggt ataatggaaa gttttatgat atgattggtc aaaaagattt
    29461 acttgataaa aatatagagg atatagttaa aaatcttaat ttaagaaaag tattaaatga
    29521 aaataaagag atgtacacag aaataaacta taaagaaaaa gaatatacaa taatttataa
    29581 tgttataaaa aatgatcaag aaaaaaatcc taaatatttg atgatattat actggataga
    29641 caagactgaa tatttaaaag taaaacaaaa ttatgatgat gaaaaaaatg caatgatgct
    29701 aatacaagta gatggatatg atgaagtatt aaaaagtgca gcagaagata agagagcttt
    29761 aattaatgtt gaagtagaga aaatactttc tgctttagaa ttaaattcaa atggtgcatt
    29821 gagaagaact tcaaaagaca aattcttctt ggtaatgcat aaaaaagagt taaaaaaatt
    29881 ggaagctgag aagttttcta ttttagatac aataagacat attgattatg gaaataatct
    29941 tcctgttact ataagtatag gaattggtat agatggagat acattaaatg agaacctaaa
    30001 acttgctacg ggtgctctcg atttagcact tggtagaggt ggtgaccagg ctgttgtaaa
    30061 aacaaaagat aaatttgtgt tttatggagg aaaatctaaa gctgtagaaa agaaaaccaa
    30121 agtaaaatcc agattaatag gtcatgcttt aagagaggtt atacaacaaa gtgaccaagt
    30181 ttatataatg ggacataaat atcctgatat ggatgctatg ggagcagcag ttggtgttta
    30241 tgatatatgt aaatcctgta acaaaactgc aaacatagtt ttacaatctg taaatgaatc
    30301 tatagaaata tttataaata aaataaatga aaataattac tataaaaagt tgtttattgg
    30361 aaaagaggaa gctattgaca actgcactaa aaatacatta gttgtagtag ttgatactca
    30421 tagaccaaat tatactgaat gtgaagaact gttaaagcta tcagagaagg tagtagttat
    30481 agaccatcat agaagaggtg tagagtttat aaatgatgca gtgcttttat tccatgagat
    30541 atatgtatcc tcaacgtgtg aaatggttac agagttagtt cagtatatgg atgaagatgt
    30601 aacaataaat aaacttacag ctgaagggct tttagcaggt ataagtctag atactaaaaa
    30661 ctttgcattc aaaacaggtg ttagaacttt tgaagctgct tcttacctta gaaaagttgg
    30721 agcagatact atagaggtaa agaaattctt caattctgat gtaaaagatt tcataataaa
    30781 agctgaaata attcaaagta ctaaaataat taataataga atatgtttag catattcaag
    30841 tactgagata gatagtataa atgttataat agctcaaact gctgatgagt tattaaatat
    30901 caaagaagta gaagcttcct ttgtattagg tgaaaaagat gatactatat ttataagtgc
    30961 gaggtcttta ggacaaataa atgtacatgt acttatggaa aaattaggag gcgggggaca
    31021 catagatata gctggagcac agttaaaaaa tgtttctcta aaagaagctt ataagatggt
    31081 aaataaaata atagaggagt atttggagga ggaagaatag atgaaagtta tattattaaa
    31141 agacgtaaaa ggaactggta aaaagggaga aatgaaagaa gtaagtgatg gatatgcaag
    31201 aaatttctta tttcctaaaa agatggctgt gcaagcagat agtgtagcaa taaaagaatt
    31261 aaatgaaaag aataaatcta aagaaataaa agcacaaaaa gagtatgaag aagcagtttt
    31321 attaggtaag caaatggaag aaattaatat agaaatatat tcaaaagcag gagaaggtgg
    31381 aagattattt ggttcaataa cttctaaaga aattgctgag caattaaaga aacaaaaaga
    31441 catagatgta gataaaagaa aaatattatt agatgaacca ataagatctt taggttcaac
    31501 tttcgtagaa ataaaaatac atcaaaaagt aactactaaa ataagagtgg atgtaaaaga
    31561 aaaacagtaa taactagagg tgattaagat ggaagatatg acgagaattc ctcctcatag
    31621 tgtagaatca gaacaatcaa tattgggttc tatacttcta gataaagatg ctataataac
    31681 ggttacagaa actataaagc ctgatgattt ctataaagag gctcacaaaa taatatatga
    31741 atgtatgata actttaagta ataaaggtga gcctatagac ttgataacat taacagaaga
    31801 actaagaaaa caagggcatc ttaatgatat tggaggaatc agttatatta caagtctttc
    31861 tactatagta ccgacgactt caaatgtaaa atactatgct gatatagtaa aagaaaagtc
    31921 tgtacttaga aagcttataa aagcttctaa tgaaataata aatctaggat atagtggagc
    31981 aactaagatt gaagatgttt tagaacaagc tgaaaagagt atatttgata tatcacagga
    32041 gaaaactagt gatgatttta aatctataaa cttagttttg atggatgcct atgatatgat
    32101 agaaaaatta tacactaaca agagtgatgt cactggtata actactggtt ttaaagattt
    32161 aaacaaaaaa ataaatggtc ttcaaaggac tgatttaata ttaattgcag ctagaccagc
    32221 aatgggtaaa actgcctttt ctttaaactt ggttcaaaat gcagccttaa aaggtgatgc
    32281 ctctgtagct gtatttagtt tagagatgtc taaggaacaa ttagtacaac gtatgttatc
    32341 ttcacaatct agtgtagaat taaaaaaaat aaagactgga acacttaatg ataatgattg
    32401 gcctagaatt atagatgcta tggcagtatt atcagatgcc aaaatacaca tagatgatac
    32461 tcctggtata aaaatatcag aactaaggtc aaagtgtaga aagttaaaaa tagaaaaagg
    32521 actagattta gtgcttattg attatcttca acttatggaa ggtgaaggta ataatgaaag
    32581 cagacaacaa gagatatcta agatatcaag gtcactaaaa atattagcaa aagaattaaa
    32641 ctgtcctgta gtagcactat ctcagttatc acgtgcacca gaacaaagag cagaccatag
    32701 acctatgtta tctgatttaa gagagtctgg agcaatagaa caggatgcag atatagttat
    32761 gttcttatac agggacgaat attatcatgc tgattctgag agtaaaaata taggagaagt
    32821 aataatagca aaaaatagac acggtgaaac tggttctgtg gaacttgttt ggcttggtga
    32881 agttcaaaga tttggggata agttgagaga cctataatct aacgaatatc cacagaacgt
    32941 cctttctttc tacaggaaaa atgtggatac atgtcactaa atatgtccaa acattgaaat
    33001 ttagctaaaa aactatccac actatccaca gatggcctgt tgataagtgt gaataagtag
    33061 ataaagcaag cttttggctt gctttatctg tgtataaata ttaattatta ggaggaataa
    33121 tatggaaaaa ataagcttaa aatatatata tcccaatata attaaagtac ttgatgaaat
    33181 aaacttattt agagtaattg acaataattt aagagaatct attgttgttt atgctaataa
    33241 tgtggataat cagtatcata taaacatgac taatacaaac tttggaaata taattaacat
    33301 atgtaaatta gaaaaacttt tagatgtgga taaatttatg gaaaaagtta taaaatatga
    33361 aaaagaaata atagagaaag aagagttttc aaaaatagaa gaatatatgt taaatattgg
    33421 agaatactaa aaaagttgaa aaaaatacga atgtttgata gaataagtaa gtaaagtgtt
    33481 cgagagtata taaaatatag aggtgaatta catgaaaaca gttgcaattg ttggttctca
    33541 atggggagat gaaggtaaag gtaaagttat agattatctt gctactcaag cagatgtagt
    33601 agtaagaggg caaggtggaa ataatgcagg acatacatta gttgtagaag gtaaaaaata
    33661 cgcattacat ctaattccat ctggagtttt aaatccaaat acagtgaata taatcggaaa
    33721 tggaatagtg tttgacccta aaggattttt agaagaattg gaaatgttta aaacggataa
    33781 tataagtaca gaaaatataa aaataagtga tagagcacat gtcatattcc catatcataa
    33841 agaactagat gcattgtcag aagaagccag aggcgattta aagataggta caacaaaaaa
    33901 aggtattgga ccttgttata tggataaaac agagagatct ggtattagaa tatgtgactt
    33961 aatggataaa gataaatttg ctataaaatt aaaagctcaa atagatgcta aaaatgaaat
    34021 agttaaaaat atatatggaa aagaagaatt atttgatttt gaaactatat ataacgaata
    34081 tctaggatat gcagagcaaa taagaaaata tgtggcagat acgtctgtta ttgtatatga
    34141 tgcagtaaga gcaggtaaaa aagtattgtt tgaaggagca caagggactt tattagattt
    34201 agatttagga acttatccat ttgttacatc ttctcatcca acatctggtg gatttgcaat
    34261 tggtgcaggt atagggccaa atatgataaa agacgttgtt ggtatagtaa aagcatatac
    34321 tacaagagtt ggagaaggac cgtttgttac agagcaaata aatgaaactg gagataagat
    34381 aagagaacaa ggacatgaat ttggggtaac tactggtaga ccaagaagat gtgggtggtt
    34441 tgatgcagtt atagttaagt atgcagctag agttaatgga ttgactagta tttcatttat
    34501 gttacttgat gtattaactg gatttgataa gataaaagtt tgtacgtctt ataaaatggg
    34561 cgataagata ataacggatt tcccagcttc attagatgat ttagcaaaat gtgaacctgt
    34621 atatgaagaa ttagatggat ggaatgaaga tataactcaa atagataact ttgatgacct
    34681 tccagaaaat gcaaagaaat atgtagcaaa aatagaagaa ctagttggag taagtgtaga
    34741 tatggtttct gttggtccaa atagagctca aactataata agaagaaata tatttgctta
    34801 atattttatc aattaaataa tttaaaatag ttgaagaaga gtatctcaag ataatgttta
    34861 tagttattag agatgctctt ttatatttga cttacattga ttttttatta agttaaagct
    34921 acttatacat attctaactg aaattaaagt tgaatttatg tagatacata taggtttttt
    34981 aaaaagaatt ttgttgaaaa taaatggcta aagatgattt taattatatt ctaaaaaaag
    35041 taaaaaaaac tattgactaa aaattatata gacgctataa tataacttgt gagtgaaaga
    35101 aacgacgaaa aaagtcgaaa aaatgtggtc tattagctca gtcggtagag cacctgactt
    35161 ttaatcaggg tgtcccgcgt tcgagtcgcg gatagatcac caaaatatgg ctcgttggtc
    35221 aagaggttaa gacaccgccc tttcacggcg gtaacagggg ttcaattccc ctacgagtca
    35281 ccagtatggg actatagctc agctgggaga gcacctgcct tacaagcagg gggtcacagg
    35341 ttcgagccct gttagtccca ccaaattttg aattagagat aaatactaga ttatatgctg
    35401 gtgtggctca acggtagagc agctgacttg taatcagcag gttgtaggtt cgattcctat
    35461 caccagctcc acaaagtaca taaattcaaa ttaatataat tttctatgtt acaggatact
    35521 tttaagtatc tttttttaat ttcattttta ttgtattaaa aatgaaatta aacatacaac
    35581 aaaattttga attacttgca atgtgatagt tttaaatata aaatttagaa tcattctagc
    35641 ataatattat gtaatatagc aaatttaatt tatagtatca ataaatatag actactaaga
    35701 atgtaaatga tttgttagat taaggtacat tagatatgta aatagaaaaa taaaaagtat
    35761 gttttaattt atgtgatata agttttaaac agagaagcaa gtttgctctt acctctctat
    35821 ttaaaaataa aaaaatgttt tttaagggct attttattta aatctttccc atctcaaatc
    35881 atctccagta aattctaaaa tcctaaactt atctaatatt ctagagagag ttctttgagt
    35941 gtaagtattt cctatttgag atggtgttaa gttggttgaa ataatgattt ttttaccagc
    36001 aacaagtctt gtatttacaa tattgaagat ttctccacta gtaaaagaat tattaagttc
    36061 agttccaagg tcatctatta ttaataaatc acaatcaaac aagtttttat aattatcttc
    36121 acttatttga ttatttgtgt ctcttctaaa tttataatct tcaagaatat ctaaaattct
    36181 aaaagaagtt tgatagatta caacattgcc tttatctaac aattcctttg caatacaatt
    36241 gcacatatag gtctttccta gtccagtaga accataaaac agtagatttt cactattatc
    36301 cttcttaaaa tcatgaacaa aattttcgca gatacttaaa ttatttagca tattttctct
    36361 aggagatatt tcaccatcag agcctttctt aggagaaaat atattcaagt taaaattcga
    36421 aaaattttcc tgacttaaaa tcctatctaa attagacatt ttataagctt catttacaat
    36481 ttcttgtttg aggcaagaac atttttctcc attaggtaaa aatcctttat ctttacaaga
    36541 aatacattga aactttattt ccaagtaatc aagaggtatg ttactttcag ctaaaagtct
    36601 ttctttcttt acttttaaag attctatatt ctctttagtc ttctttacaa tttcatcttt
    36661 agacttagga tttaaaagta ctatcttagc taaactgaga cctattttag aaatttcatc
    36721 atctatagat tttatctcag ggattctatt atatacctca ttttttctat gttctaataa
    36781 gagttcatta tcatctcttc tcttagcata tttagcaagt atttttctta ttttatcctc
    36841 attcatttaa tcacctactt aaacttttct ttttgacttt ttttaataat ctcatcgagc
    36901 tcatcagagg tatactgagt gaatgtttcg ttgaaattat gaaacttagt ttttttgtaa
    36961 gtattgttgt tttgagtagt attaatctgc ttcttattaa tattctcctt aactatacgt
    37021 tcttcctctt tttgctttaa atcatttaaa ttttttatat ttttttcatt ccaattttta
    37081 attataccat ttatataaga tatacttggg tttgaaatat tcttagactt agaacatgca
    37141 tttattatca aatctatatc catattaaat ttatcaaacc aggtgtccat aagttctttt
    37201 tctgattttg atggttgtct tgaaaatccc aattcattga aaatcgtttt atataaaata
    37261 tatcgttcac ttcttaccaa aaagctttct tcaacatctt ttggcgtata taaatttgaa
    37321 tcataccaat ttctaataat gccttcaatg tatttaactg gctttgatgt accagtttta
    37381 tctttgacgt attcatatgc gcaaagtatc atatcggggc tcatattgta tttattcatt
    37441 atatccataa tactcatctt ttcacttggg tcgagatatc gcccaactat tttatttata
    37501 gaattaaaca tttttctaat acttggattt tcagaagtag atacaacttt atctgtatta
    37561 gattttatag atgaattatt gcttaatata ttctcaatat agaaattttt taaatctaaa
    37621 aattctattg aataattaaa attatcatat tcttcattgt catgtatttt tataatcttc
    37681 ttttcttccc agaatttcca agcagataac acatcagaca atggtatatt taggtttttg
    37741 gctattgaat tattgtcgaa cttaggatta gaagtaatat cacatgcttg tctatatcct
    37801 aaaagataaa cttttacgta taacccgtcc gccattggca taaatatatc tataaagata
    37861 ttgggaatag tgatttcacc taaatctatt tcattgcttt ctttaaaaaa cattttatca
    37921 cctcagatta aattatatca ttttttatat tatatttgtc tgtaaacaaa taaaaggtca
    37981 caagattagc atgtaaatat tttctaaaag tattcatttt gaaaaggagg agatattttg
    38041 gttataaaat tcaaccaaaa agtaagaaga acattatcag tagcgattct atttatggta
    38101 ttaataatag gttgctttat agaaaaggat gacagtttag aaacatacaa agaaaaaact
    38161 aattcaaaaa taaatcagta taatatggat gttatatttg atgatgagac taagaggtta
    38221 atgtgcaatc agaatgttga ctacataaat aatacaaaat caaacataga taaaatatat
    38281 ttccatatat atccgaatgc tttttccaag aaagattttg ctccttttga aaaaagtgaa
    38341 atgacaaggg cttatcctaa tggatttaac gaaggatata tagatataaa gaatatatta
    38401 aataataata gtaaaatgga gtataaaatt aaaggagaca aaaatgacat attagaaata
    38461 gaattaggga aagagttaaa accaaatgaa agaatgtcat tagatataaa atataacgta
    38521 aaaataccaa attcaattgg aagatttgga tatggagaaa atactataaa tgttactaat
    38581 tggtttccta tagcttgtgt aaatgatgaa aggggatgga atttaaagag ttatgaaact
    38641 attggcgacc cattttatag tgagactagc gattttcatg tgaaactatt gattccaaat
    38701 aaatataaaa ttgctcatac aggaaaactt attgatgata aacatgataa taagaaaatg
    38761 ctatatgaaa tagaagctga aaacgttaga gattttgcat ttatactaag tagtaaattt
    38821 gatgtaaaca aagtagattc aaagggagta gctatcaata catataattt aaataaaaag
    38881 ctttctaaaa aagcaactga agtggcaaaa gattcaataa atatatttag tgaattattt
    38941 ggaaagtatc cttacaaaga attttctgtt gtagcaagtg acttttttat aggggggatg
    39001 gaatacccta tgcttgttat gatagaccaa agtttatata atgaaaaaaa tgaattttta
    39061 ctagaatatg ttattgccca tgagacagca catcaatggt ggtattctgc tgttggaaat
    39121 gatgaaataa gtgaaccctg gttagatgaa gcacttactg aatattctac aatagtttat
    39181 tttgaacaaa agtatggtaa agatatggca aacaagctta taaaaactat ggagatacag
    39241 acaaaaagtt atttgagtga aaatatattt aagccagcaa atgagtataa aaattctact
    39301 gaatacagct tgaatgttta tacaaaaggc gcaatagcat ttaatgaaat aagaaaagaa
    39361 gttggagata aagtattctt tgagacttta aatgagtact ataataaata taagcataaa
    39421 aatgctaatg gaagagcttt tgtggaacta tggaatagta aaggtgtaga tataaataag
    39481 attataagtg aatgtaagta aatagtgaat gtaagtaaat tttgtgcaga gtattaaatt
    39541 ttatttaata ctctgttttt ttggtataat ataatttata aggcagaaaa agaggtgaag
    39601 gaatgctaaa gtattgttca gtagggagtg gtagtagtgg taattgccac tatatagggt
    39661 ataaaaatac taatatacta gtagatgcag gattaagtgg caagagaata actacaggtc
    39721 ttaaagacat tggtgtagat gcagataaat taaaaggaat atttataaca catgagcatg
    39781 ttgaccatat aaaaggagca ggtatattat caagaaagtt tgatatacca gtatttgcta
    39841 atataaaaac atggtgttct atgaaggaca aattaggtga catcaaagat aaaaatatga
    39901 aagtatttga aaatgataaa acctactcat taggtgatat catagtaaga cctttttcaa
    39961 tagaacatga tgcgtctgac ccagttggat ataattttta tacagagagt gatgaaaaaa
    40021 tgtctatagc tactgatata ggatgtataa ctcaaaatat aaaaaaacat ctatataaat
    40081 ctaaattagt agtattggaa tcaaattatg accctaatat gcttatgatg ggttcatata
    40141 catatgcttt aaagaaaaga gtaatgtcaa gtactggtca tttatccaat gaagatgcag
    40201 ctaatttctg cgttgaactt attaatgaag gtacagaatc tatattatta gcacatttaa
    40261 gcaaagaaaa taattttcct gagttagcgt atgagacttc aaaaggagta ttagcatcaa
    40321 atgatatagt agttggacaa gatgtaaaac tagatgtact atcacgaaat gatgtttcta
    40381 atgtttatga gatgaagtag aggtgaataa ctttgctaaa gagaaatttt gaaaatgttg
    40441 aggataataa aattttatac tctataaagc agggtatgat tttagcgata cctgctatta
    40501 tgactggttc aactgctctt gtaattttga atcttccaat aaaggcttat caagaatatt
    40561 tatcaggctt gtttaatgga gaggttacaa atattcttaa ctttataaat gattctactt
    40621 taggaattat ttcattaata atattattaa caataagcta tagttatgga aaaatatatg
    40681 ggagcaagta tacagtactt gttcctatag ttgcaatgtg ctctttttta gtattttcac
    40741 atggtaatga gcttaattct tatatagaaa tatttaaaac aaagtggtta tttacatcta
    40801 taattgtttc tatgacatct tctgtattgt ttgtaaaact tacagaatct tttgttacaa
    40861 gtgtaaagtt tcatacagaa ggggctgatg cagactttaa tatggtagtt tcggctatag
    40921 ttcctttcat aatagtagta tttttgtttt ctatttttag agtggtaatg ataagtctaa
    40981 ttggcagttc aaactttcaa gatatatttt ataatttatt ttcaaatgtt tttaataaaa
    41041 tgggaacaaa ccttatgagt gctctgttgt ttattttttt aatgcacttt atgtggtttt
    41101 ttgggattca tggtagtaat gtattagata ccgtcgcaaa aaatttattt gaaaatagta
    41161 tggcaattaa cataaattta gttaataata atcaattacc aacagaaatt tttactaaga
    41221 ccttttttga tacaatggtt ttattgggag gatgtggctc tttactatgt ttagtaattg
    41281 caatttttct tagtgaaaaa cgtataaatg taagaaagtt agctaaaatt gcttcaatac
    41341 cagctctttt taatatcaat gagatgctag ttttcgggat accaattgtt tttaactata
    41401 ttatgtttgt accttttgta attactccta taatcttaac cgttacaagt tatgtggcta
    41461 tgtctacagg tattgtacca tgtacagttt cagctgtaga atggacctca cctatatttt
    41521 taagtggata tatgtctaca ggttcaataa gaggtagttt gttgcaagta tttaatttat
    41581 gtgttggtgt tatgatttat attccgttta taaaaatgtc gcaaaataga tatacatata
    41641 tgtttaaaaa taatatagaa aatttaacaa acttattaaa aaggtatgaa ttaacaggtg
    41701 aacagcctaa tcttctaaac cataatggta aaataggttc aatttcaaaa atgttggcat
    41761 cagacttgaa gtttgctatg aaaagaggag aaatagagct tttttatcaa ccacaagtca
    41821 attataatgg aaatgttgtg ggagcagagg gattacttag atggaaacat tcaataggag
    41881 ggttcattta tccaccacta gttataattt tggctaaaga agaagggttc ttagatgagc
    41941 ttggagagta tattattaat aaagcatgta ttgatttaaa gaagagtgaa aagctattga
    42001 gaaatcctgt taagttctct gtaaatatat ctccagacca acttgatgac cctaagttac
    42061 cagagcaaat aaaaaatatc attagtagta atgatataaa tcctaatatg ttaggtatag
    42121 aaataacaga gcaaattgca ttatcaggtt cacaaataat tattgaacgt atcaatgcga
    42181 tacataactt gggaataaag ttaattatgg atgattttgg gatggggcat agctctctta
    42241 tatatcttca aaataataac tttgatatag ttaaattgga tggttcatta gttaaagaga
    42301 tacttacaaa taaaagaagt agtgaaatta taatgactat tgtaaatctt tcaaaaaatt
    42361 tagattttga tatagttgtt gagtatgttg aaaatataga ccaaagggat aagttatatg
    42421 gtttaggatg tgaaatatat caaggatatt attatagcaa agcaatacct tttgaagagt
    42481 ttgtagaata tgcaaatcaa gaaagagaga tataatttta taagagcttg taaattctag
    42541 taatgcatag atttgtaata aaattaagtt taggagaaat atatgaatat aagtatagta
    42601 gtagtaggta aaattaaaga aaaatattta aaattaggta ttgatgagtt taagaaaagg
    42661 ctttctaagt attgtaagtt agaaattata gagttggatg atgaaaaagc tccagagaat
    42721 ttgagtgtta aggaaatgga aattataaaa gacaaagaag gaaagaaaat tttagggaag
    42781 ataaagcata atagttatgt tatagccttg gctattgatg gtaagggttt atcctctgaa
    42841 gagcttgcta agactatgag tgatttagca gttagaggta atagtagtct ctgttttata
    42901 ataggaggtt ctttagggct ttctgatgag gttttaggaa gggctgatta taggttatcc
    42961 ttttctaaga tgacttttcc tcatcagatg atgagattga tattgttaga acagatttat
    43021 agggcttata ggataaataa tggagaaccg tatcataaat aaatgatacg gtttttgtta
    43081 atttgacact taataatatt aaaataacaa aaaagtattg aaagtatatt gcatttaagg
    43141 tagaattaaa taaaatatta taacattata atgtttatat ggttgttaat aaaaatttgg
    43201 aggaaaatat atgataaaaa taatgttggc ctgttcagca ggaatgtcta caagtttatt
    43261 agttactaaa atggaaagtg cagctaaaga aaatggtata gagtcgcaaa tttgggcaat
    43321 accagaatca actatacaaa atgaaataga aaaatgtgat gtattattac taggaccaca
    43381 agttagatat gtattaccta aggctcaaga aattgctaag ccatataata taccagtaga
    43441 agttataaat atgatgcact atggaacagt taatggagaa gctgttttaa atagagcgat
    43501 agaacttaac aacactaagt aatataaatt ataatgtatt tttaatatat aaattgggag
    43561 aatcaaagga tggatgaaaa gactatagaa atatctttta atataatagg ttatgcaggt
    43621 gaaggtaaag gattagcttt tgaagcaata aaagaggcta agaatggaaa tatagaaaaa
    43681 gcaaaagaat tattaaaaga gtccagggaa gttataaata aagcacatag atatcaaaca
    43741 gaattaatac aaaacgaagc tagtggaaac aggactgaaa taagtgtcat acttatacat
    43801 gcacaggacc acttaatgaa tggcatgaat tttcaacagt tagctgagga aatcgttgat
    43861 ttacatttga aattacaaga taaataaaaa ttaaagataa taaattaaga gagttcttaa
    43921 aagatacatt atgtgtagca cactaattgt tagattattg attcaatatt tagtgagtaa
    43981 tacattagga ttattttgag gactcttttt atatttagtt taaagttaat aaatatttat
    44041 tattaataat ataagattat atgttataat attataacat ataatttaag aggtgaatca
    44101 tgttaagaaa tcaaccatta tatatacaag ttgtagatat attaaagcaa aaaatattaa
    44161 ataacgaata taaaattgat gaaaatattc caacagaaag ggagttagag caagagtttg
    44221 gagtcagtaa aattactatt agaaaagcta ttgagatatt agaatcagaa gggtatgtag
    44281 agaaaaaaag tggaaaaggg acaaaagtaa taagtaatag tctttttaat aagctatcaa
    44341 aagcagagtc tttttcaagt atacttttat ctaaaggtca taagttatct aaaaagacta
    44401 tttcaattga aaaaataata aatgatacaa attcacaagt atttagtata tttggagaaa
    44461 aatgtagcaa gattactaga atgtattact tagatagtaa gccatatata ttttttactc
    44521 attatattcc ttttgatgaa aatctaactg ttgaaagttt taataatgaa agttctttat
    44581 atatgtactt atataggaga aatataaata taactagatt tgaagatgaa ttttttatag
    44641 aagaatcaga actagaggta tcaaaggctc taaatctagc taaagacata ttattaggaa
    44701 gaaaaagaaa gacctatgat gagaatgata atatagttga gctatcattt gcaagatata
    44761 atacagaagt acaaaactat gtaattaaat acgaaatata ataagaatcc tgagtttatt
    44821 gaaatgataa tatgctcagg atttttgttt agttgtaaaa ataaaaaata ttataacatt
    44881 ataatgttta caactaaaca ttataatgtt ataatatttt taataaacaa gtgatattat
    44941 caattacata aaaattagtt tatgttatga aatcgttatt gcattataaa taaaggataa
    45001 tatcaataat acagggggat aactatggaa aaattcgcaa gttttttaga gcgcaagatt
    45061 atgcctgtag cagcgaagat aagtaatcag agacatatga gagctgtaag agcaggtata
    45121 atagcaacat taccactaac aatagtgggg tcatttttca caatattatt aaacatacct
    45181 attgatgctt atatggattt tatagctcca tttaaagcaa tattagatat accatttaga
    45241 tatactgtag gatttttatc tctatatgct acttttggga tagcatcatc acttgctaaa
    45301 agctacgatt tagatacaac aggtgttggt atgcttgcag ttatggcatt tttagtttct
    45361 acaatagttc caactcaagt agttgaacca gtaggtggag ttatagaagc tggtagatgg
    45421 atggatatgg caaaacttaa ttcgccatca ttatttggag ctatcgtaac atcattaatt
    45481 acagttgaaa tatatcgttt tatgaaggaa aagaatatta caattaagat gccagcagga
    45541 gttccagtag aggtttcaaa ttcatttact gcattattac cgacagcagt aattttaatg
    45601 ttattctggg taataagaca tattttagga tttgatataa gtgttgcact aagcgctatg
    45661 ttatcacctt taaaaggatt cttatcagga aatagtttag gtggtgggtt actgacagta
    45721 ttcctaataa ctttattctg ggtacttgga atacatggtc cagctataat ggggccagta
    45781 ataagaccta tatgggacat gtctatagca gaaaatataa ctgcattcac agaaggagta
    45841 tcagctcatg caatgccaaa catatttaca gaacaatttt tacagtggta tgtatggata
    45901 gggggagcag gggctactct tgcattagtt gtaatgttta tgttttctaa gtcacaatat
    45961 ctaaaaagtt taggtagatt aggattttta ccagggttat tcaacataaa tgaacctata
    46021 atatttggag caccaatagt tatgaatcca atactaggga taccatttat aattggacct
    46081 ataataatga caattctatc atatgttctt actattacag gggttatacc tatgatggta
    46141 gcaagattac catttgcaat gccagcacca atagcagcag taatgagtac taactggagt
    46201 atattagcag gtatcttagt attaatcaac tttgtgatat catttgctgt ttattatcca
    46261 ttcttcaaag tttttgaaaa acaacaatta caaagagaac aagaagaaat gagtgaaaat
    46321 ttataaaaat acatagatat agaggttttg tactatataa aatatagaaa aaacttataa
    46381 gttattaagg gtgaaggtag gaggaatgac ctttgccttt aattttatat attttaaata
    46441 atgtaatttg aggaggagaa agatggaaag aagattagga atatcagtat atccagagca
    46501 tagtaacatg gaagatgata aggcatatat aaaaatggct tcaaaatacg gatttaaaag
    46561 aatatttatg tgcatgcttt caattacaag acctaaggaa gaagttaaaa aacattttaa
    46621 agagattata acctatgcaa gagaattagg atttgaagta atccttgata tagctccaaa
    46681 catatttgat atattacaaa tatcttatga tgatttaaca ttttttagtg agttaaatgc
    46741 tagtggaata aggcttgact atggatatga tggaagtaaa gaagctatga tttctttcaa
    46801 tccatatgat ttaaaagtgg aactaaatat gagtaatgat gtagcatact tggataatat
    46861 aattacttac aagccaaatg taaataatat atatggttgt cacaattttt atcctcaaag
    46921 gggtacaggc ttgccatatg atttttttgt aagatgttca aatagattta aaaagtatgg
    46981 aataagaact gctgcttttg ttaattcaaa atatgcaaca atcggacctt ggaatataaa
    47041 tgatggactg tgtacgcttg aaatgcatag aaacttagat attgctacag caactaagca
    47101 cttattcgca acaggattga ttgacgatgt aattgtaggg aatgcatatg caagtgaaga
    47161 tgaattaaaa agaatgtctg aagtaaataa atatcaagtt gtatttaatg tagtaactga
    47221 ggaaaaaact tctgaagtag aaaagacaat aatggcaaat gagcaacact ttagaagagg
    47281 ggatataacc aaccaagtag caaggtctac agaagtaaga aaaaaatatg ctaaagaaaa
    47341 tttccctaag catgataata cgaccatctt taaaagagga gatgtagtga ttggtaatga
    47401 tgactttgga aagtataaag gggaattaca gttgatactt caagattgtg cagatgaaag
    47461 aaaaaataag gtaggtagaa taaaggaaga cgaaataatg cttttagact ttattgaacc
    47521 ttggagtaaa tttaaactta ttttagaggg agagtaaagt gaagatagac atattaataa
    47581 aaggtggaaa aacagtagat aaaagtataa ttgatatagc tatattagac gataaaataa
    47641 tagaagtaaa aaatcagata gatgattcta agtatcaggc aaatcaaatt ataaacctag
    47701 atggagaaaa atttattagt gctggttgga tagatataca tacgcattgc tacgaaagac
    47761 tagaccttta taaggattat ccagatgagg ttggaataaa aagcggtgtt actactgtag
    47821 tagatgcagg aacaacagga gctttagata taggtaaatt ttatgaagat actaaaaaat
    47881 ataaaacaaa tgtatatgct ttaataaata ttgctaagca gggaataaca tctcaagatg
    47941 aactttcaag tatgatgaat attgatgaat atgaacttaa aagagcagtt aaaaaataca
    48001 aagattttgt tgttggaatc aaagctagaa tgagtaaaag tgttgtaatt tcaaatgatg
    48061 ttgaaccttt aaaagtagct aaaagaataa aaaatgaact taatctacct atgatggttc
    48121 actttgggag ttctcctcca acgatagagg atatatttga ctatatggaa aaaggagata
    48181 tattaaccca tatatataat ggaaagccaa atggaatact tagaggcaat gaggttaaaa
    48241 aagaaatcat agaagctaga gaaagaggta taatccttga tgtaggtcat ggaaccgaaa
    48301 gttttagtat ggatattgca atgaaatcta aggatgcagg aatttttcca gacactataa
    48361 gtacagatat atatattaaa aatagaataa atggtccagt gtataatcta tctacaacaa
    48421 tggaaaagtt tatatatatg ggctattcac ttgaagatat aatagataaa gttactaaaa
    48481 atgcagcaga tgcaataagt ttaaaaaata aaggtttaat aaaagaagga tatgatgctg
    48541 atttaactat atttgatgtg gttaatgaag aaaaagaact tcaagattct ttgaataagt
    48601 cagtaatcac aagtacgtct ataaagccaa gagcagtagt agtcaatgga gaatatttaa
    48661 atataggtaa gtctatagga gagaatgagt agaagggaga aactattgta tgagtagtat
    48721 atttgaaaaa tactctgtaa gacgtgttat aaatgcttca ggcaaaatga ctatactagg
    48781 agtatcaaca gtagataagg aagttattga agcaataggt gaagggtgta aaaatttctt
    48841 tataatagaa gaacttataa ataaaacagg tgaatatata gcaaatttat tagggtgtga
    48901 aagtgcacta atagtttcta gtgcatctgc tgggattgca cagagtgtgg gagcaatgat
    48961 agcaaaagat gatatgagtc tagtttacaa tgtaaataat cctaagaaac aagttaaaag
    49021 ggaaataata attccaaagg ggcataatgt tgattatgga gttccagtag aagtaatgat
    49081 aagacttgga ggaggagaag ttgttgaggc cggctatgct aatatgtgta acaaggaaca
    49141 tataataaga gagataaatg aaaatacagc agcaattatg tatattaaat ctcatcattg
    49201 tgttcaaaag agtatgctaa gtgtattaga tgcagtacaa gttgctaaag aatataattt
    49261 acctttgata gtagatgcag cagcagaaga agatttaaat gtatattatg aattgggagc
    49321 agacctagtg atatacagtg gtgctaaggc tatagagggt cctagctcag ggttagtaat
    49381 aggtaagaaa aaatacatag ataatgtaaa gcttcaatca aagggtatag gaagagctat
    49441 gaaaatagga aaagaaaata ttgtaggtct aacatgtgca attgagagat atataagtaa
    49501 tgataaagta actttaaaag aaatggagga caagctaaat ccatttatag acaagataaa
    49561 tactataaag ggagtgagtg ctagtataac tagagattca gcaggtagag aaatacttcg
    49621 tggagaaatt gactttaatg aagatataat aaataagtca acacaacaaa ttataaatga
    49681 acttagaagt ggagagatag ctatatacac tagagactat aaggctaatg aaggcaagat
    49741 tgagattgat ataagaagtg taactggaag tgatttagat actatttata ataggataaa
    49801 aaatatagta gaaagttaga gtgtagagta agtgacatta taatgattta ataaattaaa
    49861 ttttaccaat ggaggggata aatatgaatt gtataccaca atattataaa aatagagttt
    49921 gtttaaatgt tcttgcagga agcataaaaa atgctaaaga agtatatgat gcttgtgatg
    49981 ggtatgtatt gataggagta ctatcaaaga attacagtac tgtagaagca gctattgaag
    50041 atatgaaaaa atactcaaag gaaatagata atgcaatatc tgtggggctt ggagctggag
    50101 acccaaatca gtcaaatatg gtatctcaga tttctaaaga acttcagcca caacatataa
    50161 atcaagtgtt tacaggtgtg gctacgtcta gagcattgct tggtcaaaat gatagtataa
    50221 taaatggatt agtttctcca actggtaaac caggatttgt aaaaatatcc acaggtccat
    50281 taagttcaaa agaaaaagat ggtatagttc ctatagaaac agcaatagct atgatgaaag
    50341 atatgggagg aagctcaatt aagttttttc caatgggagg gcttaaaaca aaggatgaat
    50401 atatagaagt tgcaaaagct tgtgcaaagc ataattttta tttagaacca acagggggta
    50461 tagacttaga taacttcaaa gagatagttc aaattgcact tgatgctggt gtagaaaaag
    50521 ttatacctca tgtttataca tcaataattg ataaagaaac aggtgaaacg aaagtggaag
    50581 atataggagt actttataaa ataatgaaag aattattggg atagatttat gaatatatta
    50641 gcttttggtg aaataatgat gagactttca gtacctgact acaagttctt aacacaaacc
    50701 aatgaactaa attatataat tacaggcaca ggattaaata tattatctgg acttaaaaac
    50761 tttggataca atacctatat gttgacaaag ttgcctaata ataatgtagg taaagcatca
    50821 agtgcaaata taagaaagct tggagtaaaa gatgacttta tcacatatgg agggaatcat
    50881 ataggagtgt attttcttga aaatgggtat ggagaaagac cttctgaagt gacttatttg
    50941 aataggttaa atagttcatt ttgtgagagt aaattacaag attatgatat tgataaatgt
    51001 ttagaagaaa tggatatagt ccttatttgt ggtattgcta tgcaacttac agattcaatt
    51061 aaagagattg ctttagaact agctagaaaa tcttatgaaa aggggataaa agtattcttt
    51121 gattttaatt ttagacaatc attaaatcca gaaaggactt atgatgattt agtaaatgat
    51181 tataagaaaa tactaccata ttgtcatggt ctatttgcta gttatagaga tataaataag
    51241 atacttaata tagatagtct aaatataaaa tctagttcag aattgattaa aaaagagtat
    51301 gatataggta ttgtagctgg aactatgaga agatttgatg atatgaataa tagatttata
    51361 aagggatata tatcaaatga tgatggttat tttgaaagta gggagtataa gttagaaata
    51421 tatgacaggg ttggtgccgg agatggatat gtagcaggaa ttatatattc atatttggaa
    51481 aatatgaaga gtgaagatat agttgagttt ggggttgcta gttcggtgtt agctcataca
    51541 acttatgggg ataattcttt agtaagcaca ggtcatgtac ttagacttat gaacaatgaa
    51601 aaaatagata tattgagata atacatttgt atataataaa atttttatct tttttagaca
    51661 cacttttgac ttgtttatat ttgttaaaca gagttatttt taatgattat aaatattaaa
    51721 ttaaaagtta aataataaaa tagtagaaaa tagcattaac tatagaaaaa atggttaatg
    51781 ctatttttat cgttaatatt gattaatttt atattataga aatgaacttt tctaatgctg
    51841 gatttgtatt ttttttattc catacaacta caacttcaat tctattttct acttctttta
    51901 taggtactat tgcaatatca cgttctatca ttgtatctgt aacacaaaat gaaggtaaaa
    51961 tggatattcc catgttagaa gataccaatg attcaatagt attaagatta tttgaacgtt
    52021 gtaccacatt aggtacaaac cctgcttcac gatatctatt ctgtatcatt gacttttgtc
    52081 catactcatc ccctgtttct tttacaaaaa taaatttatc atgttgtaat tcaattaaat
    52141 cgatagaatc ctcattgtaa agtggatgac caggaggtaa aagagctacc aaagaatatc
    52201 tttctacagt tttatattca aaatctttta atggttgatt ttctggatta ataacaaaag
    52261 cgaggtccat agaattattt tttactaagt ttaaaagttc ggttatttca ttagtacaaa
    52321 tatccataga tatattaggg tatgtattag aaaattcttt taaatattgt tgaagtttgt
    52381 ttttttcata tcctattaag gttccaatgc tcaaagttcc aaaaaaacca tgtgcaaatt
    52441 gttgtgtttt tgcaatagca tcattgatat tttttattat agtacgtgcc tcagataaaa
    52501 aaacttttcc agctggtgtt agttcaacat gacgtttact tcttgtaaat agagttacat
    52561 ttatttgttc ttctaaagct tttatttgct gtgtaacagc agtttgagaa atataaaatt
    52621 tttctgctgt tttggtaaaa cttaaatttt ctgctacaga tataaaatat tctaattgtt
    52681 tagtattcaa ataatcaccc ctatttaaac ttgattgttt gtaaacctta tttatctata
    52741 attaaagctt attatagtat aagaaaattt acttttaaag aatattagaa aatatttgta
    52801 taaaaatata tgttttaagt atatctttac attagatttt ataaatttat taataagaat
    52861 aacttatata ttccaatgaa aacgatattg gatttaagta agtttgtctc ataaaatgaa
    52921 agtatatcaa ttgataatac tttaaataag aagggagaaa aaatggaaga taaattttat
    52981 gcaaaaggca acggaaataa cggatatatt aaaaatcttg aagtttgttc ctttaataac
    53041 ttagatggaa cttgtggaat gtttcaaatg gctctgtaca aaagagatga aaaatactat
    53101 ttatatggat gctgttttgg aggaaataaa aaaaatggag taatgattag cgatattaca
    53161 gacccttata atccacaatt tataaaacat tttcaaatgt tagaccctaa agagtatcct
    53221 acaacaacaa ctcccaaaat tcaaatagca gatgatttaa tgatagtagc aatgagttgt
    53281 ggaagtggac caggagcact tgttgaccaa gctaaattag caaatattaa gtgtgaagca
    53341 ggaattagaa tatatagttt aaaagaagac cctttaaatc ctaagttttt aggatattgg
    53401 gattgtggct taaagcatgt aatgggtgtt catagattca tgtacaatgg tggaagatat
    53461 gtacatttat caagtgattg tgttggcttt gaaggtctga tttatagggt catagatata
    53521 ataaatccta ctaatccagt ggaaataggt aaatggtgga gaccagacca atatgcagat
    53581 ggatatccaa atagaacttt tgatgcagga gcacctcatt gcccagaatt tatggataaa
    53641 ggatggcttc atggacctcc atttgtaaga gacggaaaag catattgtgg ttatggagga
    53701 gctggtttag ttgtattaga tgttgaagat ttaacaagac caagatgctt aggtgaattg
    53761 ccatttatgc ctgcattttc tagtagactt gcaggtgcaa gaactcatac agcattacca
    53821 ttgccaggaa gagatttagt cgttgttcaa aatgagggag aaagattcca gttctttaaa
    53881 ccagataaca ttacagatgt tcaagctatg aataatatac atatggttga tgttagtgac
    53941 ccaacaaaac caacattaat tgctcaattt ccatatcctg aagttccaaa agatttccct
    54001 tatcctaact ttaatgttgc aggattagga aaaccagggc catttggtcc acataatctt
    54061 catgaaccaa tggataataa accatggtta gagcaaagag gagatagagt atattgctgt
    54121 tatttccatg cagggctaag ggtttatgat gtatcagacc catattatat caaagagcta
    54181 gcatatttta taccaccaaa tccaaataaa acaccagaag aatcttattt cccaggattc
    54241 ccaggaccac gcttggcagt aacagaagat cttatcgttg atgatagagg ctacatcatc
    54301 atagatgctt tagatgatgg attctatata ttaaaaatga aagaagatta aataaatact
    54361 aaagagggag agttgaaaat gaaaatacta ggtatttctt ttggaacaaa aaatggaaat
    54421 aatgacacaa tgtgtaaagt tgcacttaaa ggtgccaaag aagcaggggc tgaagtagaa
    54481 tttattcaaa tgtcatctat taacattaaa cattgtactg gatgttgtgc gtgtgttaaa
    54541 actttattat ctgggaaagg tagtatgtgt gtattaaaag atgattttga atggttgctt
    54601 gacaaaatga aagatgcaga tggtatagta gtttcagacc ctatttttga agaaggggca
    54661 tcaggattat tccatactat aatggaccgt tttggaccca gagcagatag aggaaataac
    54721 attataggaa caaaagttgc agaagctata ggaggaaaaa ttccagattc aagaatgctt
    54781 aatgataaag taatatcatt tatgggaata ggaggttctg actggggtac aagagttcaa
    54841 tgtgaacatg ctatgctagc tctcatacca atgtggaaag ttatagataa tgcttggttc
    54901 ccatgggcaa aggaattagt aatggatgat acaaggcttg ttcaagttca tcaaattggt
    54961 ttaaatatag ttgaagcagc aaaagatttt gaaaaagctt catatcaagg agaagaaggt
    55021 gtatgtccac attgccacaa tagattattc taccttgagc caggtactaa aaaggcaatt
    55081 tgtgctctat gtggtatagt tggagagtta gatactataa gtggaaaaac tatatttagt
    55141 tttccagaag agcaattagg tcatgctcat gatactttac caggtaagtt tatacatggt
    55201 gatgatatta agaaaatgga aggtcattat gcagaagttc gtaaaacaca agaatttaaa
    55261 gaaagaaaaa catcttataa ttttatagag acattaacta aagaaaaaca agctggagtt
    55321 tcattaggat aataattaaa atactaagac tcttttttaa gggatgttag atgttatagg
    55381 aggcttattg tatgaatgaa aagccaagtt ttaaacaaat tgaagttatt ttagcagtta
    55441 tttttttggt acttacatat tacaaggtta gattaactcc agcatttatt gttatattta
    55501 taccactata tttaagttat tttgcagtat ctatgattgt aaatcaaata gcaattaagc
    55561 tattggagat aaggcaagct agggaagcta ctaattacaa tataggaaat ggatagaaag
    55621 aaaaaagaaa tattaacact gtctatgggg attgctttac tacctccttt atgggcagta
    55681 ttagcacctt atataggaat aaaaactgga gctgtagcac taatctgtgc aggattatat
    55741 gtaactaatg gtaataaaca agaagatgga ttaaaaataa tgtttggttt ttggtgtgga
    55801 gatttatggg cagtgttagc cattttaatt atgggatata tgaatttcaa tcaaaaccta
    55861 gaattatttt taacacttag tatattaggt ttttttgcag ttgtaattgc atccttattt
    55921 gaaaaaataa ttttcctacc atcatggctt tgtggttggg ctataggtct aactattatg
    55981 acaggtgaaa atattattaa tttacaagat atttgtattc aaattgctgt agctatggca
    56041 gtaggagtat ggtacgtggg tgcaggtgta gatttgttta caatatatat tttgagtaaa
    56101 gataggaaaa agggaaattg aaagcatgtg aatatacttt gattatagga ggatggctat
    56161 gggttttgaa tttaaaataa tgagaagttt aatatatgta ggacttgcca aggaagaata
    56221 tagacctaag ctaatggact ggttatatcg tcaccatatt ccagatagta ttagcacttt
    56281 tggaccatat tgtactaaat atgcctttta tcaagcatat cctacaccaa atgaaggtga
    56341 gcgttttggt gcacgtaaga tgcaactaac agaacattat tggcttgtag atgaacatat
    56401 gcctgagatg gcaaatagaa ttatgacaga atatatgcct atggatgttc tacgttggca
    56461 agggtgtata ccagatgtag aaaataaaag ggttcatgaa aatgcagaaa gtggagatgc
    56521 aggacgtgca gtaggtggag ataatggatg tccaccattt atatttgcct ttgttccaat
    56581 aaactgggaa gaagacttta gaggaaaagg acgtactgta caagatggac caaactatcg
    56641 ttggcaattt atgattaagt atccagatgg tatctctaaa gaagaaggag aaaaatggtt
    56701 ctatgatgag gtagtgccat actttacaaa ctgttgctat gttaatcgtt ttgtcagtag
    56761 taaaataatg attaattatg gagcaactgc ttttgaccgt gtgtcagaac tatggtttga
    56821 aggggaagaa gaatggtata aagctgtggt tgaagagaca aagtcgttta ttaaaaaacc
    56881 agaatgggca caagaagagg agttcccata tttaaaacca caattcaata tcgcatcagt
    56941 attcttaggt gatatagcaa ctatggatgc atactcacag tatcgtggat atataccaat
    57001 gagataaaaa ttatagtttg tgataagtag agaaggcatt tactcttact ggtagaagaa
    57061 gacttattgt atccttaaaa gtaggtgaat atatagtttt atatttaaat ttatataaaa
    57121 ctaagactaa taaatatgaa acaatagaat tagaataatt tgataatatt tgttaaaaga
    57181 gcatttagaa tgtgtttaaa gattaagata ttccttttat ggtagcagat agttgaaata
    57241 ataaaactgt tatcatgaaa ggaatatttt tatgtatagg aaatttttaa aaataaaagt
    57301 taaatatgtt taagaacatc ttaaagtgaa agaatcattg ttagaaatat gtagacaata
    57361 tagtatttat aacgtatcat attaacaagt ttacacttgg attatgaaat aaaaagagta
    57421 attctaaagg ttgtaaatac tatgctgact ttgatacttc aaagtttagg tgattttgta
    57481 attgttaata gaaatacgtt taatgagcat aaagaattta tctaataata ggagaatata
    57541 atgtatacaa ttggacaagt atctaaattt ttaggaatat ctagagatac actaaaattt
    57601 tatgaagaca aaggattagt aaatcctaag aaaaatgatg aaaatggata tagaatatat
    57661 aatcaggttg atatctatga tattgcaaca ataaactttt atagagaaat tgatatagaa
    57721 attaaaaaga ttcaagaaat aagaaaaagt aaaagtataa acaatttaga actcttacta
    57781 gaagagaagg aacaaatcat actaaaagag atagaatata aaaagcttct cttaaaaaag
    57841 gttcagttag tcaaagaaga ttgtgacaaa atcaaaacat attttggaaa atacacaata
    57901 aaagaaatga agcctttgga agtaaaaggt aaaataaaac atgttactaa ctatgaggaa
    57961 tatgaagcct taaaagagaa tacaaacaac ttaaaaaaag cagttacatt aactgattta
    58021 agaagagtaa taaattttaa tgaagaaggt ataatagaag aaaaatttat aattgtaagg
    58081 gaagtagatg actacaacaa aatcatagaa ggtgaagttc tatctcatcc caattgtatt
    58141 tatactatta ttgaagatgg cagatggtca actggaggag aaaatattga taataaagtg
    58201 gaagacagat taagagaaat agcaatagaa aatgaatgtg aattacttgg aatagtctat
    58261 gttaatatat tgcttactac ttatgaagaa gggattgagc gtatattttt agagatttat
    58321 gcacctataa aataatataa aagcattgac ctgggactta ctcataggtt taaactcatg
    58381 atataagcag ttataactta tatagcaatt aaatattaat ttgaaatgag gattacttat
    58441 gagaacagag aaatcattaa aaaggcctat agccagtttt attattctaa caaatataat
    58501 ttttttacca ctttttttat tggtagtagt gactataatg ttaaaacttc caacagtgat
    58561 atctgacatt gcgttgtgta tatcagcgtg gtcatccact tttgcattta tgatattatt
    58621 taaaaaaatt tatccaggta agaaattttt agtacatgta aaagatagat ttagaaataa
    58681 acttaaattt tcaacagtat ctataataat tagtatacaa gtcctaatag ctgtagtagt
    58741 tatatttata ttagcatcta aaaatcatgg aataatgcct aactttacag tttcatcatg
    58801 gggagcattt atatatttat ttttaaaaaa tttatttgca ggatcattag gtgaggaatt
    58861 aggttggaga ggatttgttc aaaatcatct tcagaaaaga cattctcctt taaaagcatc
    58921 cataacagta ggtttttggt gggggatgtg gcatttacca atatggttta caacaggatt
    58981 caaaggactt gatttaataa aatatattat attttttatg attgcaatta tatcaatcag
    59041 tattataatg acaacttttt ataatctaaa taaaactttg ataataccta ttgcaataca
    59101 tcaactattt aattttttaa tagggataat taatgaagat ttaatagagc ttataaatta
    59161 ctatgcaatg ttatatttaa tatttgcaat tgcattaata gttataaatc caggaaatgt
    59221 attatataaa aatattagag agtaatatat atctttatgg taagatataa agatattatt
    59281 agaagaacat ccaaggagga ataaacatgg ttttactgat tgttgatgca caaaagttaa
    59341 taacaaacga gaggttatat aaatttaatg aatttgtagt aaatgtagaa aatttaattg
    59401 atacagctag aaaaaataat atagaagtaa tatatgtacg tcatgatgat ggagttgaaa
    59461 atgaattgac taaaggtaaa aatggctttg aaatatacga aaaatttaaa ccatgtaatg
    59521 gagaaaaaat atttgataaa aaagtaaata gtgcttttaa agaaactggt ctattagaat
    59581 acctaacaaa taatggtgaa aaagatatta ttattgctgg tctccaaaca gattattgta
    59641 ttgatgccac tataaaatgt ggatttgaac atggatttaa tataatagtt ccagcttatt
    59701 caaatacaac tgttgacaat ttttttatgt cagcagaaca atcatataaa tactacaatg
    59761 aatttatatg gaatgaaaga tatgcgaagt gtatttcatt agaggaaaca cttagaaaaa
    59821 tgaaataaaa atagagtatg aattgtatat gtacataagt tgatttcata aaaaaggatg
    59881 ttaaattcca agttaaaaat tagattaaat atattatatt atagataagg cacatcaatt
    59941 ttattttaaa ttaatgtgct ttttaattgt agtaatttat ttataatcaa tatgattttt
    60001 attatttaaa tcaatttttc ttgagtttct ttgtctaaag aaactttttt tatttataaa
    60061 atctacagtt atattatagt atctatttta gatgagttta atttttgtat caatctaaaa
    60121 caaaagttat acttaaatga aattgaaaac gataaaattc tcaaataaaa taagtattgt
    60181 ggaggtgatg aaagaatcca atgataatat gaagactaat cttaataaga aagtaggggt
    60241 taatggtagt ggacaaagaa attgtatcaa ttctccagat tttattaaat agcacattga
    60301 ttacaactaa tggattacaa gaggagtcta attcatcaaa gagacaaatt acttatagaa
    60361 taaataaaat caatgacatg cttaaagtaa aaaatgtacc acttatatgt ttaagagccg
    60421 acaaagatat tatcgttaga aaagaaacaa aaaaagcaat taaagaaatt ttagaaaaaa
    60481 actattctaa gaatacttat tattttagta agacagaaag acttttatat atgtatttaa
    60541 tgctttttat taacatggag gatatttcaa ttaatcattt tataaattct ataaaagtaa
    60601 gtaggtctac tgtaaatctt gatttcaagg atttgatacc agagcttgaa aagaagaaca
    60661 ttaaagttaa gaacaatcgt ataaatggat attacatagt tggcaatgag atggaaatta
    60721 ggagagtact tattaaaaac attatagaaa ctttgtctaa tgagaaaagt tcaagagtat
    60781 ttgatatttt tattaaagaa tataatttag atagttttga agaggctaaa aaaattatat
    60841 taaagctaat aaaaaaatat gaaattactt ttgttgaaga tagattaata gaatttatat
    60901 atatatttat ctttctaaaa gcaaggatgt attcaactag aatagttact caggaaaatg
    60961 tagatattcc taatatttca gttatgagtt caatgaagga gtataaattt gctaaggaat
    61021 tattagaagt atatgggagt gaagataaga taaagcctca caatataatg tatattagtg
    61081 cttggatttt aggtatatca gtaggaaatt atgaagaaga tacagaagat aaggatgtaa
    61141 tttcaaaaat tgtaaataaa atgatgacaa agtttggata tttaagcgga gtttactata
    61201 taagccaaga aaaaatattt aaacaattat attctcattt tagacctgcc tactatagac
    61261 ttttatttaa attacctatc tataatccga tttgtgaaaa agtaaaagaa gaatataaat
    61321 tagtttatag aattgtaagt aatgcaatga aagagttttg cggattattt ggagaagaaa
    61381 ttcaggaaga agagttagca tatcttacaa tgcactttgc aacacttttt tcaaataaaa
    61441 aagaatttga tggttttaga aaaagaatag cattaatagt ttgttcaaat ggcgttggta
    61501 gttcagctat tttacatgca gaacttacaa acttatttcc tgacttacac tttataccaa
    61561 tgtcggaatc agttggatta gaaaatataa gtgaacctgt agatattgta tttactacta
    61621 attataacgc agagggttta aaaacagatg taccagtaat taaagtaagc cctgttatga
    61681 ccacaaaaga aaaatataag attacacgtg aagtgtatat tcaattaggt gatatttttt
    61741 taagacaacc taaaatagat gaggttatgg atataataaa aaaatatgca aatgtaacct
    61801 ctgaaagtat tctttcaagt gagctattag cttattttac acagatagag aattttacat
    61861 ctaaggaagg agaggggcct atgctaagtg agattactaa tgaaacacta gtaaaaataa
    61921 aggtaaaagc taagaattgg gaggaagcta ttagacagtc agcttctgta ttagttgaaa
    61981 ataacaaagt aactgaaggg tatgtagatg ctatgattaa ctcagcaaaa gcatctggac
    62041 catacatagt aattacaaaa catgttgcac ttccacatgc tagaccagaa gctgggtcaa
    62101 aagagattgc aataggcatt gctactttag atagtcctat tgagtttggg aataacgaaa
    62161 acgaccctgt aaaatatgta ttttgtctaa gtgcaataga caataatagc catttacgtg
    62221 ctatgtctga gctagttgaa ctattggaag aagatgagtt ttttaaggtt ttagatagtg
    62281 ctaaagaagc taaagaaatt attgatttta taaaaacaca cgaattataa aggaggattt
    62341 aattatgtat aaaattttaa tcgcatgtag agcaggagtt ggctcaagtt taatgttaaa
    62401 aataaagact caacaaatta ttaaggaaaa taactttcca attgaagtag agcatggttc
    62461 attggattca ctaaatggat tcaatggaga tgctgtagaa acattaattg atgttgctga
    62521 agaattaaaa aataaaaatt tgaagtttga tataattggg attcacaata ttgttgaccg
    62581 taatgaaata aagacagcac tagaaaaatt ccttgcttca aaagagggat aaatttaaga
    62641 tgataaggag gaatatttat ggagtttatt attagtttgc tgagtacacc tgctgttttg
    62701 cttggcgtag ttgcatgtat aggattgatt cttcaaaaga aatcagctgt tgaagtattt
    62761 acaggctctt caaaaacact tatcggtttt ttgatatttg gtattggtgc ctctgctatg
    62821 acaggagcac ttcaaaattt caataaactg ttccaacatg gctttggaat tactggtgtt
    62881 atagcttcac cagaagcagc tacagcactt gcacaaggta catatggttt tgcagtttca
    62941 tgtacattaa ttcttggatt catattaaat ttagtatttg cacgtattac aaagtttaag
    63001 aatattttct ttacaacagg tcatagtttg ttcttttctt gtgtattagt tttaattatg
    63061 aaagcacatg gatttgataa tacaatcact attttaatag gtggaactat cttagggttt
    63121 atgtctgctg cactacctca attctgtcaa ccatttatgc gtgaattaac aggtggcgac
    63181 gaacaagcta ttggtcactt taacatgatt ggttatggtt tatcaggtta tattgggcgt
    63241 ttattttcaa aacataaaga tgatacaaca gagactatag aatttcctaa gtggttatca
    63301 atattcagag acttcttaat gggtctatcc atagttatgt taatcttatt ttatattgca
    63361 acattaaaag ctggtcaagc atttactcaa gaaattgctg gttcaacaca ttggttggtt
    63421 tttccgctta tagaggcatt tacatttgtg gcaggtatgt caatattgat gtcaggtgtt
    63481 cgtatgttct tagctgaaat aactgcagca tttgtaatca tttcagaaaa gtatattcca
    63541 ggttcacgtc ctgcgctaga tgttccaaca gtatttccat atgcaccaaa tgcagttatt
    63601 attgggttta tatcagcata tgctgctggt ctattagcaa ttgctattat ggcatcattt
    63661 cctagtatat ttcctgtagt aattattcca gctgctcaca tatgtttctt ctcaggaggt
    63721 acagctgcaa tatttggcaa tacttcagga ggatggagag gggctattgc tgggtcattt
    63781 gttgtggggt tattacttgc atttttacca gttatactat atccagttta tggcactctt
    63841 ggtatagaag gagcaacttt ccctaatatt gattacaatg tagttggttc gatattacat
    63901 aatattttac aatttataaa acctatttaa actaaattat ataaaagtat agtcatagtt
    63961 actatgattt caaggaggat acatcttatg gaaaatacat tatctgaatt tttagataat
    64021 atatctaatg aattgtcaga atttattgcc tcaatagatg agacatctat aaataaagca
    64081 tgcgaattaa ttcttgaagc tgaaaaaaat cacggacgtg tacatgtgac tggtattggc
    64141 aaaccaggac atgtatcggg atatatttca tcattgcttt catctactgg aacgtcagca
    64201 tatatattgc atggtacaga agcagtacat gggtcaagtg gtcaagtagt tgaaggagat
    64261 gttgttattg caatatcaaa tagtggtgaa actcaagagt taaaagcaac tcttaagact
    64321 ctaaaagtaa atggagcaaa gataattggt gtaagtggta atgagagttc atttttaaaa
    64381 aatatttctg atatattcct gtttgcaggt gttaaacagg aaggagattg tcttaataaa
    64441 gctcctcgtg cttcaatttt agctgaaaca ataatattac aatcattaag tgttgtatta
    64501 caatatgcta aaggtcttaa tacacagcag tatttgaagt ggcatccagc aggaagtctt
    64561 ggaaagtcta ttagagaggg aatataattt tatgaaatat aaagggatta tatgtgcaat
    64621 gataacacca tttgatgaaa atcaaaatat taattcacaa gcaacatgtc aattaattga
    64681 ttatttgatt gaaaagggaa tttatggatt atttattttg ggcactaatg gtgaatgtca
    64741 tgtattaaca gatgatgaaa aagttgaatt tgcaaagatt gttattaatc atacaaataa
    64801 tcgtgtacct gtttttgttg gaacaggggg taattcaact cgtgaagttg tagatttatc
    64861 taagagaatg gaagcgattg gagcaagtgc attatctatt attacaccat actttgttac
    64921 accaacacaa caggaattaa tcttacatta caaaactatt gctaattcag ttaatttacc
    64981 tattataatg tataatatgc caagtaagac tggaattaat attgaaccag agtcagtacg
    65041 tgaattatca aagataaaga atattgttgg aattaaggat agtagtggta aacttgacaa
    65101 catgaaagct tatattgaag caacgaagaa tgagaatttt agtgtgtttt caggctcaga
    65161 ttcacttatt ctggatagtc taaaagctgg tagtcaagga gctgttgcag caacaacaaa
    65221 cttcctcaca gagattggta tctctatcta tgaaaacttt atgaaagggg atttggaaga
    65281 agctcaaaaa gctcaaagta gtatagaaga acttcgacgt atactgaaac ttggaacaat
    65341 tccatctgtt atgaagaaaa ctattgtctt gaatggaatt aatgttggaa ctgcacgact
    65401 tcctgtaact gaaccaactg gggaagtact tgaagaaatt aaacgagtag ttgaaaatta
    65461 taggacaata cttaataaaa gtagtgagaa tagataatat aaatagggaa attacactgg
    65521 tatataatta atatatatat tataaaacat gactaaaatt aatgaataag taaagtggtt
    65581 tgatgagtat agaggtgata atatgaaaaa gatgaatata accaaaagaa tgtcagaatg
    65641 tggggctctt gcaattgtaa gagaagaaaa tcttaaccgt gcatgtgaaa ttgctgaagg
    65701 atgtataaaa ggtggtataa cagttataga aatgagttat accctaaata atgctggaga
    65761 aataattcaa gggcttaata aaaagtatgg tgaaacactt tgtgtgggag caggaacagt
    65821 tttggatagt gaaacagctc gtcatgctat attacatgga gctcaattta ttattgcacc
    65881 aaattacaat gaaggtgtag cgaagatttg caatagatat cagattcctt atgctccagg
    65941 atgtacatca ttgactgagg cagtagacgc actaagttta ggagcaactt ttataaaagc
    66001 tttcccaata tcagatttct atggacctaa actagtaaag gtatttaaga caccaatacc
    66061 tgatatgcca gttttagcaa gtggagggat taatattgaa aacctacata tatggttaga
    66121 aaatggagtt gatgtatgtg gatttggtgg tttattaact aaaggttctg ttgaagatat
    66181 tgctaaaaat gctaaaaaga ttcgtgaaat cattaaaaat ataagaaaaa tttaacatag
    66241 ggctgtatca tagtatctta taattactat gatacagcct ttttaatatt attcaaatta
    66301 aaaacagttt acatttctat tatattacat ataatttcag taattttatc ttaatttttc
    66361 tatctggaaa aaaatgattt aaaacttaag ttatgatata atttcattaa aagaaggcga
    66421 tttttagtaa atatgagaaa ataatgtgtt tttaggggaa aagttaaata cagatttaag
    66481 tgaacaagaa tcgataatta agatattaaa tggtgaatag ggcatcaaaa aaattactaa
    66541 attaaaagtt ttagagggag aatcttagca agtgtgtgtg aaaattcaat ttcaaacaaa
    66601 aaataattgt aaatgaaatc aatttataca cgttgaagat tcacttttat cattatatta
    66661 aaaagcagag tgaattaaaa gtgagtctaa agataggagg ataattaaaa caatgaaaga
    66721 agacattagg ttacatcgaa tgtgtaaaaa agaacaagca acaaagaatg aagttatatc
    66781 agaggatatt ctaaaatcta tgagtattgg ggtcagtaaa cattttttag atgattcatt
    66841 tacaataata tggggaaata catcattcta tcaattatta ggatatacag aagaagaatt
    66901 tttagttaaa ttttctagtt taaaagatta ttatgaacag aatctttatc attttgaatc
    66961 tatgaaaaat cattttttag aggcttatca tcatggcgaa aagagtatag aatatcaaat
    67021 ttgcatttca gcaaataatg gagaccctgt ttgggtaata atgactggta tattaattga
    67081 atcacaagat aatgagaaat caatggtcta tatattgtat tcaaaaatta atgagttaaa
    67141 aataaagcaa gaagaactat ctgatatgga aaaagagagt acagagaatt ttaaatggat
    67201 gatgtcagag tatgctggga atgtttatat tagcgatatg gatacatatg aattactata
    67261 cttaaataag cactcatgca atactttaca ggcatcagca aatgaactta ttggaagaaa
    67321 atgttatgag gtaattcaag gtagaacttc gccatgtccg ttttgtacaa attcgtattt
    67381 aaaaaaagat gacatatatg aatgggaatt ttataataaa aaactgaaac gaacatttat
    67441 aattaaagac cgtatgttga attggcaagg gcgaagagtt cgtattgaat tatcttatga
    67501 tatgtatagt gctgaatata aattagcaaa aaaagatcag gaaagagaat caattttgaa
    67561 aactattcca gcaggaatgg ttagattaga tgcaagagat tatcttacta tactttggtg
    67621 taatgatata tttttgaata tgattgaata tacaaaggaa cagtttgcag aggaacttaa
    67681 taatcaatgt ggatatttat tttctgaaga ttataaacgt agtaagaaac tggcacaaga
    67741 tttgaaggag tctggggata atgttgtatt tgaagcaaaa atatatacac gttcaaggga
    67801 agaacgtata tggactgtta cattgtgtta tatcagtggg gaagacagtt gggatggaat
    67861 accatctttt tatagtatag gtattgacat aacaaaggaa agaaaacaga ttgagaaatt
    67921 acagcatata tcagagaaag atgcattaac aggaatttat aatcgtgctg agactgaaag
    67981 gcagattaag aaatattttg aaaaaaattt aaatgttatg ggtgcactgt ttatgattga
    68041 tacagataat tttaaacaga ttaatgatac agaagggcat atgattggag atatagtact
    68101 tactgagatg gcatcaggta tgaaaaaaat aatgcgtgac agtgatgttg ttggaagaat
    68161 aggtggagat gagtttacaa tttttatgaa gaatatttcc tcagttaaag atgcagaaaa
    68221 gaaagcagaa gaactattgt atatgttccg tcatctattt cagaaagaaa aaagttttct
    68281 aaaagtaact tgtagcatag gaatagctat atatccaaag gatggtacta cattcaagga
    68341 aatatatgca agagctgata aagccctgta tcaagcaaaa aatatgggaa aaaataatta
    68401 tgtaatctac aaccaagatt attttaaaga attagaagaa tttgattgtt cttctcttgg
    68461 tacagttatt gattcagaaa aacaatacgc tgaatatcct gataatctta cacgttatat
    68521 attccgtatg ctttatcaga ctgatgatat agaccaggcg attaatatga tacttgaggt
    68581 tgttgggaaa cagtttgatg taagtcgtgt ttatattttt gaaaatacag aagatggtag
    68641 atatacttct aatacttatg aatggtgtaa tgaaggaatc tcttctcaaa tggcttattt
    68701 gcaaaacagc aattatcaag actatgagga ttatgaaaag ctttttgagg atgaattagt
    68761 tttttattgt cgagatatcc atacattaag tcctaaacta gaagaattgt tttctagtca
    68821 aggtatccac tctacacttc aatgtgcata taaagaagat agagttttca gtggatttgt
    68881 tggatttgat gaatgcacag gactacgtct atggtcacaa gaggaaataa gtacattatc
    68941 attgatttct caaattatat caatgttttt acaacgtaaa aaaaataata aacttaatca
    69001 acagattcaa caataccaga atattttaga taatattgac cagtgtattt gtgtgattaa
    69061 taaagaaaat aattttttat tatatgtaaa taaaaaattt aaaaatacat attctaaatt
    69121 ccaaattgga caaccttatt atcttgattc tatagatatt cataagatat ccattatatg
    69181 gaataaaaaa gaagcatacc tatgtactag cacgatttaa tggtaaagta aagtttatat
    69241 tggacttaaa ttaaatttcg ttttaaataa gatattattt tagttgctta ctgaaaagac
    69301 tagaatctat attaatgaat tatactaatt ttataccact attaaaatat tgtttgctaa
    69361 aaataaaaaa tagccttaaa acagttgatt ataaaaaatt aactgcttta aggctatttt
    69421 tatctttgtg acgaaataga cacttgccat ttagaatgtg acaatatagt agttgtttag
    69481 aaaaggcaca aagcattata ctttaactaa agtaaaatgt attttgcttt tagaataaaa
    69541 acaattagga gggagctata attgaaaaag ataatatatg tattatttac aattgaacta
    69601 ttaatagtat ctttattagg tctaaatata gttaaagata atgaaattaa taatatttta
    69661 tataacgaga caacaagtat atctgtaatg tttaaagatt ataaaaagtt aaataaaaat
    69721 tatagtaagt ggattaaaga tattgcagat gaaaataatg tgactatatc aaagtatgtt
    69781 tttaataata atgaaaaatt atctatatat acgactgata caagtttgaa taacaatata
    69841 aagttaaaat caggaaaatt tcctaatact aattcaaatg aatttattag taatataaac
    69901 actaataata gtaatcaagt aggtaaattc tcaactatga gtaaagacat atcaatttta
    69961 attagggatt ttggtaaaat aagtgaagtt ggagaatcag gaatcttata tatttcaact
    70021 caaaatgaag atacaataaa taaaatatta agagaactaa atgtagacag aagtattttt
    70081 gtagcaagat tacatgatag atatgttaac tcaaatttat acttaaatcc ttcaataatt
    70141 agagatttaa tactaattat cctttgtttc ttggctacaa taatacatta ttcaattagt
    70201 gtgagtagag aggcttctat tttaagatta aatggatact ctaagctaga tataattgct
    70261 agagttataa aaaatatact tagaattatg attttatcat ctgtcacagc attattaata
    70321 tatataatct atattttaaa attaaatata ggtgttagag catgcttata ctttgctatg
    70381 ttttcgatta tatgtatttt gataaatatt ttgatatcta tattaatagt tggttttaat
    70441 agtagaagtt ctaaatatgt gctatctcta aatggaaaaa aatcttatgg ttttgtaaat
    70501 ataatgcatt tcacattgaa aattgtattt gtatcatttc ttatattatc cataaataac
    70561 tgtattttaa attataatat gctacaaact cagttaggaa atctatctga gtgggataaa
    70621 gcaaaaaatg tttataatct tactcttaaa gatacaggcg aacaatcttt aggaaaggaa
    70681 gaagtaatta aaaatgccaa gattaaaggt ttctataaaa atttggtaga agaaaaagat
    70741 gctttcttaa tagattcaac taattttgaa aaacttgaag atggaagtta catgtatgaa
    70801 ataaattcaa agggtaaaaa cccagaagta agtcaatatg gtaaaaatat aaaaataaat
    70861 aaaaactatc ttaaagttaa ccctatttac tcaaatggca aagaaatatt taatctaatc
    70921 gattatgacg ataagactat aaatttatta gttcctaaaa agttacaagt acatgaaaat
    70981 gagattaaaa aagagtttag agaattattt tattttgaaa aaatagaagt agaaaatatg
    71041 tacaataaag agttaaatag agcgttaaac aaaacaaaga agtcagattt aaatgttaat
    71101 ataatatatg tagataataa tcaaagctat tttacttata actcccttgt tatggatgac
    71161 aataggaatc tcattgatga cccaatagca atagttgaca tagataatat tgatgattct
    71221 ttttatcttt cttatatatc tagatgtgta tattttaatt ctaagaaatt agatgccctt
    71281 gcagatataa gtagcattat tgaagctcaa ggtgtagaag cgcatatcca aagtttacat
    71341 gctgtttata atgagtatgg tttagaaata aataaactag aaaaatattt gaatagtgaa
    71401 atttttacta taataataat agcaatatca aacttaatga ttacctacaa tatagtagct
    71461 agctactatg aaagaaataa atataagtta tatattaaaa aaatatttgg ttattcaact
    71521 acagctagaa gtatgttgtt aatagtctca ttaatattaa caaacattat tccaataggc
    71581 attatatcaa caagagtaga tttaagtaat aatattatct tatttggact tctaatatta
    71641 gttatagaag taattgtatc tattgtatta gacaagatta tctcaaatag ttcatttaat
    71701 aaaattataa aaggagaaca ttaaaaagat gatttcatta ataaatatat ctaaaaaatt
    71761 taaagataaa tctataatag acaaatttaa cctagaaatt tctaagggcg agtttgtagc
    71821 gataacagga aatagtggtt caggtaagac aactttactt aatataatgg gattattaga
    71881 aaaacctaat tctggtgata ttataataaa taatataaaa aatccaaata gtaaacagat
    71941 aagaatttta caaagggatt tttatggcta tctatttcaa aattatgctt taattgagaa
    72001 tgaaaatgtt gaaaataact tgaaaattgc tttaaagtat caaaaaaata tcaaccataa
    72061 taaaaaaata aattacgcac ttgagtctgt aggtcttaga aaatacaata aaaaaaagat
    72121 atacgaattg agtggaggag aacaacaaag ggtagcatta gcaagagtaa tattaaaaga
    72181 atgtgaagta atatttgcag atgaacctac aggtaattta gataaaaaaa atagagacat
    72241 agtatttgat atacttaaaa gtctaaataa gaatggtaaa actatcgtat ttgtaactca
    72301 tgatttagag ttatcggagc aggcagatag agttataaaa ttgtaataat atcaactata
    72361 ataaatataa gaaagagatt acagctaaat caagtttaat aataatacga atagaattta
    72421 aacattaagt aaattagtag tttgtaaata taagtataat atgatatcat aaaggctcaa
    72481 aagaaatttt atataataag aaatctaaaa ataacaaatg gaggacatat aaagatggaa
    72541 aatttaccaa attgcccgaa atgtaattca gaatatactt atgaagatgg aactctttta
    72601 gtttgtccag aatgctctca tgagtgggca ttaggattgg gagctgaaga agattcaaat
    72661 attatcaaag atgtaaatgg aaatgtatta aatgatggag attctgttac agtaattaga
    72721 gaccttaaag taaaaggaag ttcatcatct ataaagattg gaacaaaagt gaaaaatatc
    72781 cgtttaatcc atgactcatc agatggacat gatatagaat gtaagataga tggttttgga
    72841 gctatgaagc taaagtcttc tgttgttaaa aaagcgtaat attataaata agctgtagtg
    72901 tttattgttt ttcagtacag tataaaacca taagaatcta ttaagtaata aaagtttgtt
    72961 tatttatctt tatattttct tatggtttta ttaaatataa attttattga acaccaaaat
    73021 attctctcct ctacaaataa gccaatctta tttaaattaa tatactttgt actatttata
    73081 ctgaaattgt aaatttaaat gctatgttat ttaggtttgt atagttaatt tatatatttc
    73141 tgattttata aattgtattt attattatat cttgattcta aaatcattaa aaatttcaac
    73201 ttctataaag atttacaatt tatcaaatac attatgagta tataaacaat ttattattac
    73261 agtgctacat ttaaaataag tcttagtata aaggtattgt tacaagtata aagaaactta
    73321 tgtatgctat tggaataaat aataccttaa attataataa agaataagaa ctgttaaata
    73381 agggacttga ttatcattta gttatagata atataatatt aaaaataaag tttaagagga
    73441 gaaaaaatat gatagatata cataaaaata tatatgataa taagttattt gaggagctaa
    73501 agattgactg taagaagtgc tttggacttt gctgtgtagc tctttatttt tctgcttcag
    73561 atggatttcc tatcgataag gaatcaggaa aaccctgtat taatttacaa ccagatttta
    73621 aatgttctgt acataatagt cttatgaagc gaggttttaa agggtgtact gcatatgatt
    73681 gttttggttc aggtcaaaaa gtagcacaag taacatataa ggggatagac tggatgcaat
    73741 catcagaact aacaaatcaa atgtctgaag tgtttttaat tatgagacaa ttacatgaaa
    73801 tgttatggta tcttaaagaa gcatctgtat taaatatatc agatacaatc aaatcaaaaa
    73861 ttgatttaat aattgaagaa actgaaaaga taactaatat gagcccagaa cagataatta
    73921 atttggatat catatcacat agaataaagg ttaatttatt attatcacaa gcgagtgagt
    73981 ctgtgatggg aaaggttaaa tcatttatca agacttctac tcttaaaaac atgaaaaaat
    74041 taagtaaaaa tatagattta ataggagcag accttagaaa aataaatcta ataggagcag
    74101 atttaagagg tagatttcta atagcagcaa atttaagaaa tacagatttg agtggggcaa
    74161 atttaatagg agcagactta agagattgtg atattagagg tgctaatctt gaaaatagta
    74221 tatttttaac acaattacaa gtaaatactg caaaaggaga ttctagtacg aagttaccag
    74281 cttcactaat acgccctaaa tactgggaaa aataattaaa ttaatacata attttacaaa
    74341 acatgaactt ttttgacttt aattcatatt atacattaga gattctttac aagaatttct
    74401 taatataata tagggagaga tataaaaatg agttatcaaa attataaatg tgaaagagat
    74461 tatgtgtatg atgattataa atacaataag tgcaacaagt gctataatga ttatgaggaa
    74521 atgacacatg ttcatgaata ttcagaaagt gttaagttag cagaagaatg tgaggataga
    74581 cataaccacc gtgcagcagg ggttactggt gaagctatac caataaatgg aggtacaaat
    74641 catgttcata aaataaatga taatgtagat ttccttgacc atttccataa gatatgtgtt
    74701 acaacagggc cagcaattag aatacctgga actgataaac acattcactt aatatgtgga
    74761 gaaactactg ttaatgatgg tcattgtcat aaattccttt ttactactca aatagaagca
    74821 cctttagtat aagctgatgt gaattattgt agtgaatttg ctagattata gtataataat
    74881 atataataga taatatttaa acttaatgag gactatgata tttaaccttc gtagtccttt
    74941 ctaagttttg tataaaaaag tgttatgcaa ttaaaagtga tatagggagg aaatttttat
    75001 gaaatctgga ataattcttg aaatgaaaca aataaattca acagaatatg acgaaatgtt
    75061 gcaagtctgg gaatcatcag taagagcaac gcatgatttt ttaacagaaa aagatattga
    75121 atctttgata ccattagttg agattggact taaagaagta gaaaatatag tttgtataaa
    75181 agataatgat ataataaagg gctttatagg aatagataaa gataaaattg agatgctctt
    75241 tatagaagat aaatatagag gaaatggtat tggtaaaaaa ttaataaaat atgctataga
    75301 taaatacaat gtaaaatatg ttgatgtaaa tgagcagaat aaaaaagctg taggatttta
    75361 tattcactta ggatttaaag tgtttgatag gtctgaaata gatggacaag gtaacccatt
    75421 tccaatacta catatgaaat taatttaaag ttatacttct catttattcg caaaaatatt
    75481 tacttaaatt tttatacaaa taaaagtcgt gacagtctta ggacacgact tttttactac
    75541 actattaaat tgaaatttat ctgttctata ttatgattat tagatgtcgt ttttttattt
    75601 taactatgta cttaaatacc aagtataccc atacctatca agtacttcag cagcgccatc
    75661 attttgatgt ggtggtgggt gtggtaaaaa ttcttgtaca agtgtaccac cttcggcaag
    75721 ttttacagat atttcttcta tcgcttctcg agatggtaga acaacacaaa tcgccatgcc
    75781 agaaattaca acaggcttgt ctgtatccgc acccattata caaccttcgt attttgtgaa
    75841 agtaacactt gcgtgcataa taggattgtt tggattgctg tctaatcgcg caaatatagt
    75901 ttttcctcct ccgaaagcct cagcataaaa attaaatgct ttttcacaag taccattaaa
    75961 tattaaatat ggagttagca tgaccaatat atcctccttg atatagaata atttatagtt
    76021 gcacctgata atctaaatta tgatttagta aattgtatca tagggaaacc ttgaagtata
    76081 taatttttta ttattatatt atacaaattt attaatttaa aaaaatgtta tatgtacgga
    76141 aggtttacag gataaaatat aataaaaaga ttaaggtgac attataaaaa atgtatattg
    76201 acattgacgc tacgtaattg tatatacttt gtcttaaagg agatggtaaa tatgaatatt
    76261 atagaaattc gctcagataa aatatacaag aagataatgg atgcaccaat aaacaaaaaa
    76321 gaagatatat acagatatga attgatgaag ccttttgaat ttaagtggaa gtgtatgaat
    76381 gttccaatag ttgctagaca gaaaggtgga tatgatgtaa ttatagcaag tgaaatgtta
    76441 ggggttttat cgcctaagga tattgatgaa aaacaaaaaa agaatataaa tgtgttatct
    76501 gctgataaaa tttgggccac ttgtaaagaa accatagaaa actctataaa tgcttttata
    76561 aaagaagggt atgatttaaa tattaaggac tataaatatt caatattatt ggcgaatcca
    76621 aatagtcctt atacaatatt aagtgatgga tactggggtg atggtgggat tcctggatat
    76681 atatttctat cattggttcc taatgaatat actatcaata gattaccagt attaatagca
    76741 catgaatgta atcacaatat tagatttcag tttatagagt ggaataataa tataacatta
    76801 gaagaaatga tgataaatga aggtcttgca gaaaattttg caacatggat gtttggagag
    76861 gaaatgttag gaccttgggt cagtagaaca gatatcgaaa cattaaatac ttatataaag
    76921 ccaataataa aaagtgcttt aaaagaaact ggatttcaaa atataacatc ttatctttat
    76981 ggtgatgata tagctaaaat gcaaggatat tttccagtag ggttgcctta ttgtgcagga
    77041 tatgcttgtg gatattatat gattaagtat tatttagaaa agacaaataa atcaataatc
    77101 gaagcgactt tattgcctta tagtgagata atcgaagcag taaaagagtt ttgggaataa
    77161 attttataaa ttgcataatt tgaaataaat tatgcaatta ttttattttt aagaaaaaat
    77221 aaattgacaa taatttataa gaaatataca ataatatata taaagaaata tttcaatatt
    77281 taaaagtttt aagatttcat atctagagta cctaacatta catgttagtt tcttgttact
    77341 tatctaatta ctttatattt cgtagttata tataaaatta ctataaaaaa tgaaatatat
    77401 taaacaatca ac
//
LOCUS       DAMJVG010000007        77280 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.007, whole genome shotgun sequence.
ACCESSION   DAMJVG010000007 DAMJVG010000000
VERSION     DAMJVG010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 77280)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 77280)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..77280
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.007"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            786..2456
                     /locus_tag="PC512_000561"
     CDS             786..2456
                     /locus_tag="PC512_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF and EAL domain-containing protein"
                     /protein_id="HDF2440334.1"
                     /translation="MREESNSLSLDHIEIFFELLSQSTEDYIFFWDINRNKFKISSAI
                     FDEFNLSKEIESDLVNCWSKIVYPDDVQIWKDDIQELLHGKKGEHNLEYRLINKYKEI
                     VWISCRGKVYVSDDPKTIFLVGRIKNIGEKNKFDSITGTWNREQFEHKMNYLIKEKIY
                     KNGAMFIMDIDNFKNINEKYGHSYGDKVLRAIATEVLEYLPKDVRLYRLDGDEFAFFY
                     PMCTKETIEKIYEKIQMYTNTQHEIESSKYYCTVTAGVAMYPEDGDNYLDLFKHADIA
                     LDIAKISGKNRIKFFSQELYENKLKVISMQQKLRECVENNFNDFELFFQPQVNAVTKE
                     VIGAEVLLRWHSSTYGEVSPVEFIPILEQSNLIIPVGKWIIKEAVKQCKEWHKINPDF
                     KISVNVSYIQLKEDFFRDFIVECLVEYQLRPEFLILELTENCWIPDINLLNDKFISLK
                     GIGVYIAIDDFGTGYSSLNYLKELSVNIIKIERSFVKNITYNSYEYTFLEYIIKLAHI
                     INLKVCVEGIESYEEYDIVKSLGVDIIQGFLFGRPVSASEFYKFQLSK"
     gene            complement(2578..3312)
                     /gene="pflA"
                     /locus_tag="PC512_000562"
     CDS             complement(2578..3312)
                     /gene="pflA"
                     /locus_tag="PC512_000562"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HDF2440335.1"
                     /translation="MIKGKIHSIETFGTVDGPGIRYILFFQGCPLRCKYCHNRDTWDI
                     KSGKEYTVDEIITDALKYTSFMKFSGGGITASGGESTLQPEFLSELFKKAKENDIHTC
                     LDTSGFVDIETIDPVLDNTDLVLLDLKHMVEEKSIDLTGVGMDKALKLARHLESRNIP
                     VWIRHVLVPGITDDIDNLEKLGQFVATLKNVERFELLPYHSMGIHKWESLGIDYELKD
                     VPDATKEDVQKASEIISKFGVKVYNS"
     gene            complement(3472..5703)
                     /gene="pflB"
                     /locus_tag="PC512_000563"
     CDS             complement(3472..5703)
                     /gene="pflB"
                     /locus_tag="PC512_000563"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HDF2440336.1"
                     /translation="MNAWQGFKTGRWTKEINVREFIQLNYSPYEGNDSFLAGATENTK
                     KLWDEAMVLFKKERENGGTLDVDTKTVSGIAAYAPGYLDKELETIVGLQTDAPLKRAV
                     MPYGGIKMVENSCEAFGYELDPEIKDIFTKYRKTHNQGVFDVYTPEMRAARKSGIITG
                     LPDAYGRGRIIGDYRRVALYGVDALIEDKNEQKKSLEVSCMDEEVIRLREEITEQISA
                     LNELKKMAESYGFDISKPATNSKEAVQWLYFGYLGAVKDQNGAAMSLGRTSTFLDIYF
                     ERDLKAGIVTEEELQEYMDHFVMKLRMVKFLRTPDYNNLFSGDPTWVTECIGGMGIDG
                     RTLVTKNSFRMLNTLYTLGPSPEPNLTVLWSTKLPQGFKDFCSKVSIDTSSVQYENDD
                     LMRAYWGDDYGIACCVSAMRIGKQMQFFGARVNLAKTLLYAINGGVDEKSGVQVGPRF
                     EPITSEYLDYDEVMSKFEPFTDWLATLYVNTLNVIHYMHDKYSYEALEMALHDRDIFR
                     TMACGMAGLSVCADSLSAIKHAKVKTIRNEQGIAVDFEIEGDYPKYGNNDDRVDSIAV
                     ELVESFMNKIRKNKTYRNSYPTQSILTITSNVVYGKKTGNTPDGRRAGAPFAPGANPM
                     HGRDTNGALASLSSVAKLPYEHAQDGISNTFSIVPAALGKDMTERINNLSAMMDGYFA
                     QNAHHLNVNVFDRATLEDAMEHPEEYPQLTIRVSGYAVNFIKLTKEQQLDVINRTFHG
                     KMA"
     gene            5996..7057
                     /locus_tag="PC512_000564"
     CDS             5996..7057
                     /locus_tag="PC512_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium/sodium antiporter"
                     /protein_id="HDF2440337.1"
                     /translation="MEKRKSIHLHKLNIYLIGGGDRLFITVVLFLVGFLLITKGADIF
                     INCTVEIGKKTNISEIILGATIVSFATTLPEFTVSLLASIDGHTTMSLGNAVGSIICN
                     TGLALGLVVFISPFNVDKKMFFSKSLLLIVSVIVLILLSLDGVITRGDSLLLIIILIF
                     YMVNNYRSVVGKSDTKNRNIKNNTIKDISTKKGKNYRGFSVLEIVKILLLFATGLIMM
                     IIGSQILIESGVIIASFLNIPQGIVSLTIIALGTSLPEIVSSITAIRKNHHEISVGNI
                     LGANILNIVSVIAVSAIPNNIPILSQNRQLDIPFMILLLLIVIIPTLKSNRLSRIQGI
                     LMLFTYFLYISILYFMYII"
     gene            7148..8761
                     /locus_tag="PC512_000565"
     CDS             7148..8761
                     /locus_tag="PC512_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDF2440338.1"
                     /translation="MNITKFEDLPISEGIKKAIAEMGFEEPSPIQAQSIPAILSGKDV
                     IGQAQTGTGKTAAFSIPILETIDPNNRSLQAVVLCPTRELAIQVSTEIRKLAKYSHGI
                     KTLPIYGGQPIDRQIKSLKSGVQVVIGTPGRTIDHINRKTLKMDNVKMIILDEADEML
                     DMGFREDIEMILSKIPEERQTTFFSATMPRGILELTKRYQKDPEHIKVVRKELTVSNT
                     KQYYIETRSSNKLEVLCRLVDVYDPKLSVVFCNTKRKADELVGDLQARGYFADALHGD
                     LKQTQRDIVMDKFRNGTIDILVATDVAARGIDVDDVECVFNYDLPQDEEYYVHRIGRT
                     GRAGREGMSFTFVFGKEMRKMKDIERYTKSKLIKHNIPTITDVEEKKVGTFFAQVKQT
                     IEEGHLTKQLQWLEGFCNDEDYAMVDIAAALVKLSLGEEMKEEIIEEKPRRERGDRKG
                     GTGAKDGMIRLFINIGRNQRVQAKDIVGAIAGEVGIPGKVVGTIDIYDKYTFVEIPKK
                     DAKTVIEKMKDIKIKGNKINIEKANKKKK"
     gene            9036..11021
                     /locus_tag="PC512_000566"
     CDS             9036..11021
                     /locus_tag="PC512_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HDF2440339.1"
                     /translation="MSMTYMDPRVFLILEMVLEEDTNTLEQFSNVLGVSTRTIRNYIN
                     QINRELKGGIAKIVKNEKGTYSIRIEDESKLIEIVNFNRGKLSNFINLNSPDERINYV
                     LDILTMTNNPITIDDLAEEICIGRTTLIKDLKKADRILAEYDLELKRKPNIGMILVGE
                     EMDIRLLILDRLYENYIDVLENVNQINLVKDYDIECLRDELKKLFKKEELYITEQVLR
                     DVERYIIMSVLRNLNGYKFEKIDKRFEVIRCSDEYTLGLKLKALLEKIFNIVLNEKET
                     IFLTMPLIGRKAPSTKLALSSIKINDSVKEVVDEVTSFLLETSGIDFKEDKKLIENLE
                     YHLYFALNRMRFNIRVKNPLLQEIKERYTFPYSVAKIAAMIIEEKFDLKICDHEIGYI
                     ALHFGSYFEKNSRKVLNVNRVAVVCGTGLGTAQLIRIKIGKILGESVEVNTFSDIEAK
                     ANLDLLKYYDLVFTTVDFKTDLDVPIFRVNALFNEESIKKEIENAILLKNSINLKSIK
                     KIEKNIPFIGKLIEEDKFFILNKSTFMENLEDMLEKLVHKGIIDIEFKKKVLKREKKS
                     STALDNYIALPHSVNTNGENLYLAFGILEKPVIWDTKEIRIIILMIIPDKNVDSTDLI
                     IKSYEEVLEVGRDKKMVEELAKVKSFDEFYKIITKRR"
     gene            11026..11460
                     /locus_tag="PC512_000567"
     CDS             11026..11460
                     /locus_tag="PC512_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HDF2440340.1"
                     /translation="MDPVIFIIASLITVYLLNIFLGYLQLKDFNKNYIELKRKGRVAI
                     GRKKGRISSGTIVLILINDDGVIVETRKMQGVTVLARVKSFEGLVGKSLEYIEKSDLT
                     VYNKLLKKAILDAVKQYITFEKNKCEDTNNLSTDEECRMEVV"
     gene            11489..12049
                     /gene="srlA"
                     /locus_tag="PC512_000568"
     CDS             11489..12049
                     /gene="srlA"
                     /locus_tag="PC512_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418408.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HDF2440341.1"
                     /translation="MTQFFQVLASGADSFMNLFRAGGQQFVGFVTDIVPLLVALLVTM
                     NAIINFIGTDRVERLAKKCSANIFTRYLILPVLGTFVFANPMTLSLGRFLPEKFKPSY
                     FAAASFSCHTMNGLFPHINPGELFIYLGIANGITTLGFSTADLAVRYLLVGIVANFIK
                     GVVTDYTTKFVEKQQGIALNSDIKIG"
     gene            12113..12481
                     /locus_tag="PC512_000569"
     CDS             12113..12481
                     /locus_tag="PC512_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sorbose transporter subunit IIB"
                     /protein_id="HDF2440342.1"
                     /translation="MAFNKVKIVKGSGGWGGPLIIEPTEKKNKVVYVTGGAKPETAVK
                     IAELTGCELIDGFSQGVKDDEIACVIINCGGTLRCGIYPQKKIPTINIMKTGKSGPLA
                     MFIKEDIYVSGVKPTNVEQL"
     gene            12506..13072
                     /locus_tag="PC512_000570"
     CDS             12506..13072
                     /locus_tag="PC512_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003374365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HDF2440343.1"
                     /translation="MAYDTKKKISEQSQGIVAKIGIALGNVTSTLFQAGRDTIDTLIH
                     TILPFMAFVAVLIGIINQSGIGNWVANLLTPLIGNVGGLVVLSIICSFPLLSPFLGPG
                     AVIAQIVGVLVGTEIGKGNIPPSLALPALFAINSQAACDFIPVGLGLAEAEPDTVQVG
                     VPSVLYSRFLTGAPTVLLAWLASFGLYK"
     gene            13113..13478
                     /locus_tag="PC512_000571"
     CDS             13113..13478
                     /locus_tag="PC512_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HDF2440344.1"
                     /translation="MELIYSTQINKIGDNANEFLQHNMFVTFKDNAPQELENYCYIHS
                     ENNLVKEILTDDVLSINNVDYKITSVGELVNQNLSELGHITFKFTGEKDGAIGGTLYL
                     EEKEIAPIGVGTILKIIRK"
     gene            13579..14352
                     /gene="srlD"
                     /locus_tag="PC512_000572"
     CDS             13579..14352
                     /gene="srlD"
                     /locus_tag="PC512_000572"
                     /EC_number="1.1.1.140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sorbitol-6-phosphate dehydrogenase"
                     /protein_id="HDF2440345.1"
                     /translation="MRKVALVVGGGRSLGEYLSKHLAKVGYDVAIADLNEDNAKKVAE
                     EIKTEFGCKSVGYSCNAIDERQVISTVKAIENDFDRIDLLVYNAGVAVSKKITDFGYK
                     DFKFIVDVNLNGYFLFAREVSKVMIAKGIEGRIIQINSKSGRVGSKHNSGYSAGKFAG
                     VGLTQSLALDLAEHKITVNALMLGNLLDSDMFESLIPQYAVKLGIPESEVKQVYIDKV
                     PLKRGCRFIDVANMLTFYASKEAEYCTGQSINITGGQVM"
     gene            14701..17139
                     /locus_tag="PC512_000573"
     CDS             14701..17139
                     /locus_tag="PC512_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HDF2440346.1"
                     /translation="MDIIKKLSHGCTLDCHDCCKFNVYTKGNNVVKIEGDKNHPYTKG
                     FICKKGMAHLDRLNHKDRIKTPMLKVDGVWKEISFDKAIEIMAEKLTYYKEKYTSKSV
                     MHYDQYGSGSVLKYIGDIFFNFYGGVSRHKGGPCWSAGMHAQKYDFGVAKSHAIEDML
                     NSKSIFVWGKNPAYTTIHTMQIIKKAKEKGIKIVVIDPIYTKTAQIADKYVQVNPGTD
                     GALAIAMAKIIVEDKLYDEEYINSYVIGFEEYKKYLSSLELSFLIDECGVKENDIREL
                     VDLYTNKYSSINVGYGLQKYKNGGNTIRAIDALGAITGQIGFSGGGVNYANKVYPSVI
                     NSDPYNSQSYGEDREFYVSNISKFIEESLKNTSNKVNYASDELDMALHKVNYISDELD
                     TTSNKVNYVSDELDMALHKVNYVSDELDTTSNKVNYVSDELDMALHKVNGVSDELDMA
                     LHKVNCVSDELDMTSNKVNYVSDELDMTSNKVNYVLDELDITSNKTDYISNELYNLSN
                     KSIKDNIPIKMAVITKSNMLNQLPDLVELERVFSKIEFKVCFDMFITDTVTLCDMFIP
                     CTNTLESEDIIYSSMTNPYITYNERAVKPAHKLMDEYYFFMELAKKMGLNDYPFVEKR
                     TYLEKVIEPLKRFDKNLDIEKLKNNYFTIHNPVAWEDKKFETPSGKYELYSESIKNLG
                     ISPTPVYISNKYKEIEDKNISFRLLTNHHADTLFSQHFMDKKSIAQAYINQRMAKKVG
                     IEEKDIVILRSKKAKINVQINIDDGVGNYIVKMYVGWWKKHGNPNSLTDTGISDFGGQ
                     VTYNESMVEIIRQN"
     gene            17227..17562
                     /gene="spoIIAA"
                     /locus_tag="PC512_000574"
     CDS             17227..17562
                     /gene="spoIIAA"
                     /locus_tag="PC512_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma F factor antagonist"
                     /protein_id="HDF2440347.1"
                     /translation="MVNYSLEHKNLYIEFMCSELDHHVANEIREEIDNLLSVNQVKNV
                     VFNFENINFMDSSGIGVIIGRYKKISNEGGRVSVINISSRVKKIFDLSGLNKIIGIYD
                     TYEEALSSL"
     gene            17576..18004
                     /locus_tag="PC512_000575"
     CDS             17576..18004
                     /locus_tag="PC512_000575"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma F factor"
                     /protein_id="HDF2440348.1"
                     /translation="MNNIMEVKFSAISENESLARVIVASFAAKLDPTVDELVDIKTAV
                     SEAVTNAIIHGYEEDSSKFVFLRCEIEGNTIKIIVEDEGYGIENVEKAMEPLYTSKPE
                     LDRSGMGFTVMKSFMDDVEVSSVKDNGTRIEMTKKINVPK"
     gene            18027..18791
                     /gene="sigF"
                     /locus_tag="PC512_000576"
     CDS             18027..18791
                     /gene="sigF"
                     /locus_tag="PC512_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigF"
                     /protein_id="HDF2440349.1"
                     /translation="MEVTVAREEKKPLLSHEETLELIEKVQNGDEEAKEILISSNLGL
                     VRSVVSRFLNIGYDREDLFQLGSIGLIKSIYKFDPKFNVKFSTYAVPMILGEIKRYLR
                     DDGMIKVSRSLKQIAVKAKMESEALTKKLGREPSIEELAKAIDVEKEDLVMAMEANFN
                     VEYLQGVIHEEEGSPICLIDKISMKGESEEEKVVDNILLKDILGRLDKRERQIIVLRY
                     FEDMTQSEIGEMLNISQVQVSRIEKKVLSKLKEYIS"
     gene            19071..19508
                     /gene="spoVAC"
                     /locus_tag="PC512_000577"
     CDS             19071..19508
                     /gene="spoVAC"
                     /locus_tag="PC512_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AC"
                     /protein_id="HDF2440350.1"
                     /translation="MDKNYKKYVDQISPKPTYLKNYTLAFIVGGIICMIGQAINDLYM
                     KVGGLDKLGASSATSITLIFIGAFLTGLGVYDLIGKRAGAGSIIPITGFANSIVSPAM
                     EYKREGYVLGVGANLFKIAGPVLVYGIGSSILCGIIYYIFKMF"
     gene            19675..20688
                     /gene="spoVAD"
                     /locus_tag="PC512_000578"
     CDS             19675..20688
                     /gene="spoVAD"
                     /locus_tag="PC512_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AD"
                     /protein_id="HDF2440351.1"
                     /translation="MKNKRIGKRTVKLENKPTIISTGTIVGPKEGEGPLKDYFDMIMT
                     DDLYGEKTWELAESKMVETASQQAIQKAGKKLSDVNYMLGGDLINQIVPASFAARELA
                     IPFLGIYGACSTMAEGLCIGSMLIDGGFADLVLSGTSSHYCTAERQFRFPLELGNQKP
                     MTAQWTVTGAGSVLLAPNGDGPKVKYVTVGKVIDEGIDDGNNMGPAMAPAAIDTIYSY
                     FEDTNDDPNSFDIIATGDLGTLGKQIAEDFLKEKGVDISKVYTDCGIEMFNLKEQDVH
                     CGGSGCGCSATVFAGYIYDKLRKKEFNKVMLVSTGALLSPTSTLQKQTIPCVAHAVVI
                     VNE"
     gene            20702..21064
                     /gene="spoVAE"
                     /locus_tag="PC512_000579"
     CDS             20702..21064
                     /gene="spoVAE"
                     /locus_tag="PC512_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AE"
                     /protein_id="HDF2440352.1"
                     /translation="MLMDYVRVFIVGGIICLIAQVMMDYFKMQTPYVMVTYVTTGVVL
                     TFLGLYEPLVKFAAAGATVPIIGFGYSLATGVIKSIQSDGFLGIFLGGTTATAGGIAA
                     AIFFGYIMSVVFTPKAKP"
     gene            21247..22263
                     /locus_tag="PC512_000580"
     CDS             21247..22263
                     /locus_tag="PC512_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDF2440353.1"
                     /translation="MVTIKDIARNLGISYSTVSRCLNNNPNVSEKTKKKVVEEANRLG
                     FHFNVNARNLAKKETNRIGVIFSNNFNHQDTRKFFSDIMDSSINSIETNKYDFIIQPN
                     NNISGDSNVYKMVNGQMVDGLVIVSQSIKKEEYDFLKDNNFPHVFIYFKPSFIGEVDN
                     FFWDDNVYGGYIATKHLIDHGHKDIITVTSDDKSSKMHEDRTKGYLNAMEEANLKTEV
                     IKSKMDFESQVEFLEKYIDKIKKASAIFVQQDVPAISIIQELKTTYGINVPEDISIIG
                     YNNIELISYFRSHLSTIDDPREQVIKNGVDSLVNIINKKSTEHIPRKLYPRLIIRNSV
                     KRIK"
     gene            22638..23480
                     /locus_tag="PC512_000581"
     CDS             22638..23480
                     /locus_tag="PC512_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3100 domain-containing protein"
                     /protein_id="HDF2440354.1"
                     /translation="MKEKAGIRNAIIAAFIITILAELIGPISFKVMGINVTLLSILWA
                     IFIGMAVSPHLLGRVIPALKKFIGDNEINVSPYLLSLTLYPLGIMFGINAGPKVGILL
                     QAGPALLLQEFGHMGTMLIALPVGVALGLGRSALGGTFSLCRDTALGIIGDKYGLNSP
                     EGIGTLGTYISGSIFGTLLFSFLAPVGVLLGFHPYALAMASGMGSGSMMGAATASLMN
                     TVPQMSEQILAYSATSGLITAVTGIYIELFLSLPVANYYYSKVAPVIERFRGRKTRRT
                     SNKL"
     gene            23495..23959
                     /locus_tag="PC512_000582"
     CDS             23495..23959
                     /locus_tag="PC512_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440355.1"
                     /translation="MEKTFKTIMEQIKIVLFIYIIICFGQMIALKTQAQDLLIGSVSG
                     FLLVIIAIIIKNFVKKPNLPGFAWATLVAFVLSLPISPVGDIIATNVGKINFMSTVTP
                     LLAFAGISVGNQLDILKTLSWKLVVISFIVMTSTYFGSAFISQTVLRLNGML"
     gene            23946..25118
                     /locus_tag="PC512_000583"
     CDS             23946..25118
                     /locus_tag="PC512_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDF2440356.1"
                     /translation="MECFKEVVNMNELKAKIKEEIKLLSEEKKTSFEKVSDYLFSNPE
                     LAFEEYKSQKALCDLLEENEFNVTKGVGGLETSFEAVYSNGTNGKTVAFLAEYDALPG
                     MGHACGHNIIGTSSVGAGIILKEIMKKHNIEGTVKVFGTPAEERVGGKITMIKEGVFN
                     NVDAALILHPSDASMPDDISFAQVNLKFDFTGKASHAAAFPWEGKSALSGVIALFNSV
                     NSMRLHLKDYARVHGIITDGGSIHNIIPEKSTAIFNVRALSIEYLNEICEMLKNCAKG
                     AAISTGTNVEIVQLDEIYKEIKNDSELVNIVRQNFEVLGEDYVERDLSQGIGSTDTGN
                     LTHEIPAIQAYIKLKENTATHTDEFAVAAGGEEGRVALIKAIKVLAMCGVDILYSK"
     gene            25162..26097
                     /locus_tag="PC512_000584"
     CDS             25162..26097
                     /locus_tag="PC512_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1177 domain-containing protein"
                     /protein_id="HDF2440357.1"
                     /translation="MILKQVIEVYDILDKANANGEEVKTYLQGYGEVDVTVKELSSSK
                     GSTDLVKLTIPGKNGKLKGGDAPTLGILGRLGGIGARPEVIGFVSDGDGALVAIAVAA
                     KLLDMQRKGDILDGDVVISTHICPDAPTKEHYPTPFMDSPIDMMTMNENEVDSSCDAI
                     LSIDTTKGNRVINTRGFAISPTVKEGYILKTSDNLLDIMQTVTGKSPFVFPLSIQDIT
                     PYGNNLYHLNSILQPAVATDAPIVGVAITTEMPVAGCATGATNFSDLDSAGRFAIEVA
                     KLFGRNKCDFYDKEEWEMLIKRYGKLNRFQTFGIQ"
     gene            complement(26371..29064)
                     /locus_tag="PC512_000585"
     CDS             complement(26371..29064)
                     /locus_tag="PC512_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HDF2440358.1"
                     /translation="MNNDNDKNGNKIRRKKVSSSGNTNKPINRTSANKTRSTKNKKKS
                     KKSDKFKKLRVFGIVFLVLLVVGTAGTAGLVFASLRDVTPVTEAVLDKQTNQTTTIKY
                     ANGKTLSTAPSVNKKTPVPLDKISPYLQHAVIAIEDERFYEHKGVDIKGLFRSVLKTL
                     TGTKQGGSTIPMQVSKMLLTTEQQTIPRKIKDIYYAHEMSKTVSKDKILETYLNNFFV
                     GRGLAGAEAGARGYFDKSAADLTLAESALLAGSTKNPSRFSAYKTSKLEGNETKEDLE
                     NKLLFFVNTTDDDLDDPTQVDFDMIEKIKSWELISNDTYRQLKAGTLVVRKAVSNPEA
                     KKRQEIVLKKMLELKYIKQSEYDEAIKAKIEIKLPQSSDKVSSSVEDLIESEVINALM
                     EQGHTNDEAQNLFYNGGLIVNTTIDPKMQDALEEEFDRNSNFPGHMVGPDGVSQPQAA
                     MVILDYKNGEIRALAGGRNISGRKTLNRATNPHQPGSSIKPLAIYTPAIDTLKITQAT
                     ALSDSRGGYKFKENNEWNPRTTTAGHGSMSLRKALAKSSNTIAVKTAEMLGDSYDECV
                     DIMMDYLKNFGITTLKNNHSGSSEASDRKFPSLTLGGMANGITPLQMAAAYGTLANHG
                     IYVEPSIFTTITTFDGQLLVKNAPEEHKVVDPEVAYVVTDMLESVITEGTGGVATLPK
                     GMPVAGKTGTTNSAYDAWFVGYTPYYVGATYIGDDAGRKDDSGNTIKRREVPHGSTST
                     AKLWEKIMEKIHANLTVTEFEVPKNVYFTKINLEDGGKQSSGSKAAFIEGTAPTKVSS
                     QPSSEDTKKPDNNQPEENNNNNNNTGDNGGGSTPPDNGGNNGGGSTTPPDNGGNNGGG
                     STTPPDNGGNNGGGSTTPPDNGGNNGGGSTTPPDGGGTPAT"
     gene            29278..29976
                     /gene="yunB"
                     /locus_tag="PC512_000586"
     CDS             29278..29976
                     /gene="yunB"
                     /locus_tag="PC512_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YunB"
                     /protein_id="HDF2440359.1"
                     /translation="MNRIVDRKTKNEFRKIIAIFLVILFLSVFIGSFIYIDKTLRPTI
                     TVLAETKALELANRSINKAVAEMVEGKINYEDLMDIQLDNNGKITMIQANTIMMNEIA
                     SAIALEIQDELKKDKTASSYIPIGTALGSPILAKYGPKLEVSIEPIGTVSVNFKTEFE
                     SSGINQTRHRIYLEAQTQVKVVIPLITSTKQIKAQIPICETIIVGDVPESYVNIPEKN
                     LGNVLPNTGKNTNK"
     gene            complement(30192..31205)
                     /locus_tag="PC512_000587"
     CDS             complement(30192..31205)
                     /locus_tag="PC512_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S55"
                     /protein_id="HDF2440360.1"
                     /translation="MQLKNFHFKNNTLSKKTNLAKSKFTIVLTFLFLFLLYFFSNNLI
                     YAQNLQKNEPEYLIPIGNVLQIDAELKNIIVRNPGEASPFRLGDAIVKVNNAEVDGYS
                     DFANTLNALPEEKQVSILLNRGGQLITMKTTKHILEKISFNNLLSGFATLTYINPDTS
                     EFGAVGHPISVGNARKIPIKTGSISTTKHLNIEKSYKGSVGCINAKRENIIGSFTENT
                     DFGIRGQINNFDISKLKKYKVASLDEVKLGKAQIILQDNFNKCKKYNIEIIDIENQKH
                     PESKSFKIKITDKKLLAQTGGIVQGMSGTPIVQDNKIIGAVSHAIENDPAVGYGVFIK
                     WML"
     gene            31433..32317
                     /locus_tag="PC512_000588"
     CDS             31433..32317
                     /locus_tag="PC512_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF2440361.1"
                     /translation="MKKYRLLVTCIIAMGIIIIGTSNPVSNFYKTTNLISSGNITNEK
                     ANKDENSNKNNKDKNEDKSNSKSNKDKSSEDKSSDNKNEIQKNKKLLICIDPGHQGKG
                     DSNLEPVAPGSSSKKARVSSGTEGIATKKPEYVLNLEASLVLKSILESKGYNVIMTRE
                     THDVNISNSERAILANDKKADMVVRIHADSLNNSSKTGASILIPEKDGKYTAPIYEES
                     NKCAEFIKQNMEQSGIQINGIVQRGDLTGFNWSKVPAVLVEMGFMSNYNEDQMMSNPD
                     YQRKMMQCIADGLDAYFK"
     gene            32519..34069
                     /locus_tag="PC512_000589"
     CDS             32519..34069
                     /locus_tag="PC512_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDF2440362.1"
                     /translation="MLVVENVSHGFGARTILENVSFRLRKGEHIALVGANGEGKSSFL
                     NIITKKLMPDAGNIKWSSRATVGYLDQHTVLSKGKTIREVLREAFKHMFDLEQEMIAM
                     YDKMGEASDDEMSKLLEETAEIQTILENSGFYMIDAKIQEVANGLGLGEIGLDKDVTD
                     LSGGQRTKVLLTKLLLENPTILILDEPTNYLDEEHITWLTKYLQEYENSFVLVSHDIE
                     FINNTCNVIYHMENGELNRYKGNYDEFVRLNDIKKRQEEQAYDKQVEERKRLEDFVAR
                     NKARVATRGMANSRQKQLDKMEILERPKEKIKPTFAFKDARAASKIIFETENLVLGYD
                     EALTKPLNFHLERGKKIALKGMNGIGKSTLLKTLLGIIKPFEGNVKLGDYLEVGYFEQ
                     ESSRENSNTPMDEVWSEFPGLTNFEVRQALAKCGLTNEHITSQMRVLSGGEAAKVRLC
                     KVMLKNINFLVLDEPTNHLDVEAKDELKKAIKEFKGTVLLVCHEPEFYSEIVDDVWNI
                     EDFTTKIV"
     gene            34098..34745
                     /locus_tag="PC512_000590"
     CDS             34098..34745
                     /locus_tag="PC512_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HDF2440363.1"
                     /translation="MKKFLNVLFSICISIVIIVGVINFTVGFKQLYYFDIDYLNISEL
                     SGLSKDDIKLNYDYLIDYNLNKNVSEFKLPTLKSSPQGKIHFEEVRNIFQNINKLAKL
                     LLVVSLVGIILSVKNKNIKILKTTSITLIIMPLLLTVPILLNFEKSFIIFHKLLFRND
                     YWIFNPDLDPVINILPEEFFFHSGMMILILILLVSIVLFVMYKLCKSLSIKIFQC"
     gene            complement(34887..35147)
                     /locus_tag="PC512_000591"
     CDS             complement(34887..35147)
                     /locus_tag="PC512_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich small domain-containing protein"
                     /protein_id="HDF2440364.1"
                     /translation="MGENYKFFNHKDCEFFPCHKTNKPEEFNCLFCYCPLYALGENCG
                     GNFKYTDKGIKDCSSCILPHKKDNYNYIMSKFQDLVKITSKK"
     gene            35364..36647
                     /gene="hflX"
                     /locus_tag="PC512_000592"
     CDS             35364..36647
                     /gene="hflX"
                     /locus_tag="PC512_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HDF2440365.1"
                     /translation="MKEIQEKALLVGLNLTTIVKKNDDIDTNESMEELKELTKAAGAE
                     VVGSLIQNKHSVDAAYYIGKGKVEEIRAYSDSLDATLVIFNDELSGAQIRNIENVVGR
                     KVIDRTTLILDIFAQRALSKEGKLQVELAQLKYRLPRLYGMGGEMSRTGAGIGTRGPG
                     EQKLEIDKRHILNKAADIRRELKEVKKNRETQRVKRLKSNIPIVALVGYTNAGKSTLL
                     NELIKTHKDYEQEKEVFVKDMLFATLDVTLRKALLPNKKEFLVVDTVGFVSKLPHDLV
                     EAFKATLEEVQYADLILHVIDATNTSYELQKSTTEGVLKELGVNDKKHILVYNKVDKL
                     ELDIYPKSQEDIVYISAKQGINMDKLLNMIEIALMENTYSVSLMLPYERGDIFSRIKD
                     KYNVENFEYGESGITLDVDLDEEDFNIYREYILEK"
     gene            36655..37332
                     /locus_tag="PC512_000593"
     CDS             36655..37332
                     /locus_tag="PC512_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HDF2440366.1"
                     /translation="MDINWENIDNLEDYFITYLLYKESKTVSQISKIRNISSTEASEQ
                     LIQAKLKIKEMQKDDFEASKDILDKFLELDKIKRLDFMDSLDDEKMVYFKRKVFKRIL
                     VEKNAEDLIVLIWATGELKDDRFLKLLHQLTNHRHSDIRRITYSAIRKIESPSSREVL
                     QKGLYDKNAQTRQYCAKALSKLGDENSLKILQQLKDKNKNFEKEYVLRAYDKAIKSLE
                     NAKNLKK"
     gene            37418..37861
                     /locus_tag="PC512_000594"
     CDS             37418..37861
                     /locus_tag="PC512_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HDF2440367.1"
                     /translation="MIVRRCAGGVVFYANKVLIVKNDRGEWTLPKGKILGGGLPYESA
                     VQRVKVETGIDAKMIDVAGDTMYEFFSRSRQQEVCNAIMWYVMEACNTDCVLAPEFQE
                     GGFYKVKDALEMLSHHKEQALVEVSYKKFKELKKLVSEGDDVPAN"
     gene            38166..38810
                     /locus_tag="PC512_000595"
     CDS             38166..38810
                     /locus_tag="PC512_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HDF2440368.1"
                     /translation="MSNYRTLHEFGMDEITIEKSVFIGYAKPIKSEEEALEFINEIKK
                     KHKDATHNVWAYTVGKNMNIQRYSDDGEPQGTAGIPTLEVIKKEDLRDVAVVVTRYFG
                     GTKLGAGGLVRAYTKGAKLGLEAGKIIYKVMYQEVKVKIDYTQLGKVQNELMNLGYFI
                     KDTVYEDNVEIVVYSRLEDVEKLSEKMIDITSGTGKIVLGEEFYLSEQNGEILI"
     gene            complement(38896..39273)
                     /locus_tag="PC512_000596"
     CDS             complement(38896..39273)
                     /locus_tag="PC512_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HDF2440369.1"
                     /translation="MLFALIGFFAGIIGGMGMGGGTILIPALVLLAGIDTKIAQSVNL
                     LSSIPMTLIALAIHIKNKNVIFKLVIPIAVFGVLGAVFGSLLANYLSSDILKKIFGIF
                     LLLVGLFEVKKGFCAKSDKKPLN"
     gene            complement(39273..39659)
                     /locus_tag="PC512_000597"
     CDS             complement(39273..39659)
                     /locus_tag="PC512_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HDF2440370.1"
                     /translation="MKKTDDLKKKYFDFNLKNTIIGVFTGFINGVFGSGGGTLLVPIL
                     NDIVKVEEHKSHATALSIIIFLTTASSVLYVSKGTYDVNLTIKVAVGSILGGIIGAKL
                     LNKVTGKFLRISFGIIMIIAALRMVF"
     gene            39838..40593
                     /gene="nadE"
                     /locus_tag="PC512_000598"
     CDS             39838..40593
                     /gene="nadE"
                     /locus_tag="PC512_000598"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+) synthase"
                     /protein_id="HDF2440371.1"
                     /translation="MSNIKIQIDKTVEWLINKVNEANAKGLIVGVSGGIDSAVVANLI
                     KKAFPENSMGVIMSIKSNPQDREDALKVIEGCDIEYLDLDLIEPQSAILDMVVGNLKD
                     KHLYREEYLKMTDANLRARVRMSTIYTIANNLGYLVVGTDNAAEIHTGYFTKFGDGGV
                     DILPIANLTKGEVYEWAKELGVHEDLINKAPSAGLWEGQTDEDEMGTTYNMIDAVLEG
                     RLDEVPKRDQEIIERLHRLSEHKRKTPAQPPKF"
     gene            40676..41395
                     /locus_tag="PC512_000599"
     CDS             40676..41395
                     /locus_tag="PC512_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDF2440372.1"
                     /translation="MGRIGNIINRKGKQDAQRAKIFTKHARAIAVAAKEGGADPEYNA
                     ALKTAIEKAKADNMPNDNIDRAIAKGAGAGAGEDYETIVYEGYGPGGVAVIVETLTDN
                     KNRTAGNVRYYFDKNGGNLGTSGCVSFMFDKKGQILVGLGDGVSEEELMDVALEAGAE
                     DFITEEDGYEIITTPEDFSSVRDELKAKGYEFISADVKMIPQTTTVLTEESHLKMMNK
                     LVDMLEEDDDVQDIYHNWEVE"
     gene            complement(41562..42566)
                     /locus_tag="PC512_000600"
     CDS             complement(41562..42566)
                     /locus_tag="PC512_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HDF2440373.1"
                     /translation="MATIKDIAKDCGLSSATVSYVLSGKGNERRIPLHTQELILNSAD
                     KLGYKRSTPIKHNNIKIAFYWQDEGFELASTNILQAINHIISLEHLNINIIIRPYKVG
                     HLCDDEYFFANNYYDGIVLTGINADDIEYLVKNKPKIPVVVVNREIPGFSSVSIDNEE
                     TGRIAALHAIQNGKNDIAVVFNPTSFTCMTLRGKSFLKTCKEHGIHLSDSIYYCSNKI
                     DSGYDIAQKMLAKNSLKKVIFCNHDVVALGMMNAFHESGIVIGEDIQIFAASNGPSRL
                     MARSIPPLTVIDLKMEETAERSLRMIIDTVTGRINGIQQQVIYPSIIYRQSSPAQNLL
                     "
     gene            42832..43728
                     /locus_tag="PC512_000601"
     CDS             42832..43728
                     /locus_tag="PC512_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="HDF2440374.1"
                     /translation="MSKVNIFEVGPRDGFQNLKEFLETDKKLKIIDGLIASGIKQLEI
                     SSFVSPKAIPQMKDAKEVATYCVEKYPDVKLYALVPNLYGAKVAWECGIRDISYVISL
                     SETHNKKNINRTHEESIDELKKIMNTYPDMNICIGMATVFGCPFEGLPKIEDAIRFAK
                     RLWENGIREMNLADTIGIADPKQVRETISALVEALPECRWQVHIHDTRNMGMVNTLVA
                     IESGITTVQSTLGGLGGCPFAPGASGNTATEDLVYMLERMGYDTGVDFVKLLELSKYQ
                     KSFVNGVYSGHHVNIKSDSCNC"
     gene            43866..45128
                     /locus_tag="PC512_000602"
     CDS             43866..45128
                     /locus_tag="PC512_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440375.1"
                     /translation="MDIIALLLFLGVIIIAFVRKNNAGILALAIGVIAVRIFGMDDKE
                     LYGAISNSMFTTLVGITLLFAIVNSTGALKLVAEKIVAASGKRVWLIPIAVFIAGFVV
                     AGVGPGAIPALAIIPAMAVPVAITVGYNPVMLALIGECGLMAGRMTPITPEGQIITTV
                     AEGVGIENVMPTILACQTLSTIVFSIVLFIIFKGYKLKKPINVIDSKQIEKFNIKQII
                     SLISIVVMIAFIIIFDMNVGLAAFAVSAVLIFFNIADEGECIKSIPWSTIVMVLGVGA
                     MMTIVDAAGGIDLMSNALSSLMNSKTATPIMSISAGLMSMVSSALAVVYPTMMPMCVD
                     IAKAVGGVDPLALIAAVGVGGSLAGVSPLSTGGALILAAMGSSKKDFNKEEQNKVFVQ
                     LFIMSAVGLLVIAVVSILSFNAITHLMN"
     gene            45204..46397
                     /locus_tag="PC512_000603"
     CDS             45204..46397
                     /locus_tag="PC512_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase"
                     /protein_id="HDF2440376.1"
                     /translation="MKKGALSNIKVLDLTRVLAGPYCTMMLADFGADVIKIEMPRKGD
                     DTRGFGPFVNGESLYYANINRNKKGITLNLKSEEGKNIFLEMVKHADVVVENYRPGVM
                     EKLGLGYDELAKVNNQIIYGAVSGFGCYGPYSERPGYDIIAQAMGGLMSITGQEGGEP
                     TRVGNAMGDVLGGMNLTIGILTALNARKIIGKGQRVDVSLVDSVVSSLETGIQRYFDS
                     GQPELMGNRYASAYPYDSFKASDGSFVIGCGNDKLFEKLCKKVLFREDLLIDERFKTN
                     LNRCEHYKALKPEIEKWSIKHTIKEAVDLISEAGVPAAPIYNLDCVTTDEHIAKAREM
                     IVDISHPIIGNMKVNGNPVKLMTTKAKIDMPAPSLGESNEEIYNGWLGFDSDKIKDLK
                     ENGVI"
     gene            47026..47820
                     /locus_tag="PC512_000604"
     CDS             47026..47820
                     /locus_tag="PC512_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="HDF2440377.1"
                     /translation="MESVMENLNNLKVEVKDKVCVITINRPKALNALNSDTLRELSQV
                     IDVVSENEAILGVIITGEGKVFVAGADIRQMQNYKSEEGRKYAGYAQGVFDKIEALEK
                     TVIAAVNGYALGGGCELAMSCDIRIASEKAIFGQPEVNLGVIPCFGGTQRLSRLVGTG
                     IAKELIFTGRQVNAEEAKSIGLINKVVPSDLLLEESMKMMNQIVEKAPIAIRYAKVVI
                     NKGIDMDLKNALELEKDIAGLTFATRDKQEGMNAFIEKRKPVFENK"
     gene            47915..49255
                     /locus_tag="PC512_000605"
     CDS             47915..49255
                     /locus_tag="PC512_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HDF2440378.1"
                     /translation="MNTGVIISLVGIIIALSLLVVMVMKGINIFIIAIVCSSLVAITG
                     SLNVYDALKVDYMTGFVGFLQANFFIFLTGTLMGKIMEITGGAKSIAKMIVRWIGKDK
                     ALLSIPIACGILAYGGVSVFVVSFAVFPIALEIFKEADLPRRFIPAALTFGCSTFAMV
                     APGAPQIQNIVPASTLGTDIMAGAVNGFISCAVMFIVGSTILYKMVSKEKANGGHFIA
                     HESDIFDEAEATNSKRENGPNGVIALIPLIVSILIINVKVNGKAIVPIEVGVFIGALL
                     VYLLLNKYQDNTKIVGHVGDACKTTVVAICNTCAVVAFGSVVKSAVGFDFIVNAMTNI
                     PGPPIAGAAVGTTVIAGICGSASGGLGIAAPLLGPVFLAKGVSAAALTRTMAISSAAL
                     DSLPHNGYIVTVTNGLCKETHKDAYMPIFWVTVLTPFIGTIVAVLLFTMFPGLP"
     gene            49392..50624
                     /locus_tag="PC512_000606"
     CDS             49392..50624
                     /locus_tag="PC512_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase"
                     /protein_id="HDF2440379.1"
                     /translation="MLNKPLEGVKVIDLTYFVAGPGTSKILADWGADVIKVEPSFGDP
                     GRKTGATMTMPIDDYNNPFYSTYNSNKRGLSINLKSETGIEIMDKLLSEANVFVSSYR
                     TGALKRLGLDYESLSKKHPHLIWGQINGFGDFGPAKDNAGFDTVAFWARSGAMLDIAE
                     KDTSPINPPIAFGDATTSCSLSGGICAALYQQAKTGKGQKVMASLFGQAIWNASSLLA
                     STQFSDEYPKTRKNAISPVINSYRCKDGKWIFLSILEHERYFEALCRLFGREDLIKEE
                     KFASSVESKKNATELINILDGEFAKFTQNEMVEKLTAADIAHEKIQHVNDVVTDEQAI
                     ANNYIYEHTSKDGNKTMLASTPVKFGNIEVNMTCDAPLIGEHSDEILRELGYSDSDIE
                     ALIESGIVTMNKEACEIC"
     gene            50664..51806
                     /locus_tag="PC512_000607"
     CDS             50664..51806
                     /locus_tag="PC512_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="HDF2440380.1"
                     /translation="MDFRLTEAQLMLQRVAKEFAENEIAPIAAETDKTGIFPRELFSK
                     MAKIGFNGIGTPVEYSGSGGADIEKVIVVTEIAKKCAASAAILSIHTIYAQAILKFGT
                     EEQKKKYLPMMAEGGCVGAFALTEPNAGSDAARAATTAIIDEETDEYVLNGTKCFISG
                     GGQAESLIIFALTDPSKGIKGMSAIIVDKGTPGFSIGKIEEKMGIHGSETAELIFDNC
                     RVPKSNLLGKEGKGFNIAMTCLDGARIGVGAQAVGIAEGALEESIKYSKERVQFGKPI
                     SALQGIQWYIADMATMVESAKLLVYYAADLKARGEKHTKEAAMAKYNASRTAREVTNL
                     ALQIHGGYGYMKDYPLERMYRDAKITEIYEGTSEIHKVVISRAVLG"
     gene            51817..52611
                     /locus_tag="PC512_000608"
     CDS             51817..52611
                     /locus_tag="PC512_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HDF2440381.1"
                     /translation="MNIVVCLKQVPDTNEVKINKETGTLIRDGVPSIINPDDRNALEE
                     ALKMKDELGAVIKVISMGPPQAKSALKEALAMGADEAYLISDRAFGGSDTWATSTIIA
                     AAIEKVGKYDVIFCGRQAIDGDTAQVGPEVAEFLGIPQVTYAKEVKVQDDKLLVTRYT
                     ETGDYLIEAKMPVLLTAIKELNNPRYPSVKGILEAYNNGDAKITVLTLADLDVDTTQI
                     GLKGSPTNVYKSFVPVKDKHNEIIEGINKKEKAEKLIEILFDLKLV"
     gene            52622..53644
                     /locus_tag="PC512_000609"
     CDS             52622..53644
                     /locus_tag="PC512_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HDF2440382.1"
                     /translation="MMRAKVNQGINLNDYNGVWVIGEQREGKINPVTIELIGEGRKLA
                     DQLGKELAVVIAGYEVEKEVKELLHYSVDKVYYINDPLLKDFTTDGYAISIANLIERK
                     KPEVVLVGATSIGRDIAPRIAGKVGTGLTADCTKLEIDSTDNKLLQTRPAFGGNLMAT
                     IVCPKNRPQMSTVRPGVMAKAVRNESETGILEVVTPELTEKMIRTRLVEILPQEKKSV
                     NLTDARIIVSGGRGLKRAEGFELIKELADKLGAEIGASRAAVDSGWIEHSHQVGQTGT
                     TVRPELYIACGISGAIQHLAGMSDSKYIVAINKDAKAPIFSICDYGIVGDLYEIIPEM
                     IESLNR"
     gene            53743..55119
                     /locus_tag="PC512_000610"
     CDS             53743..55119
                     /locus_tag="PC512_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent Fis family transcriptional
                     regulator"
                     /protein_id="HDF2440383.1"
                     /translation="MKEQWYKDIFARVLSMTDDGFIVVNRSGVIIDINDKYCDFLGKE
                     RKDIIGQNIQSIIPNTKMLDVMKNKYCEEGAIHHYSGGNTKEKSVIVSRSYVENDNGE
                     VVAGVAQVKFRLQSFDVAKKLMSEYMELQYYKEQFKDNCGFDKLIGENRDFIELKKTG
                     VKASKTNFPVLLTGETGTGKEVFARAIHNNSSRSDKPMVSINCAAIPEELLESELFGY
                     DEGAFTGAKKGGKKGKFLVANNGTIFLDEIGDMPLTMQAKLLRVLQESEIEPVGGLKT
                     IKIDVRVISATRKNLSKMVEEGLFREDLYYRLNVINIHMMELKDRQDDILLLANYILN
                     KLNVEYKELKVLSDKVKNCFINYTWPGNIRELQNVIKSAYAVSDDMVIMMCDLPSKMD
                     NISRVAQCNVDSNCSIHEMVENYEKSLIIDVLRKYNWKCSKAAEVMGIHKSLLYKKIK
                     KYEIELNN"
     gene            complement(55451..55795)
                     /locus_tag="PC512_000611"
     CDS             complement(55451..55795)
                     /locus_tag="PC512_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440384.1"
                     /translation="MDQIKRLHELQQKSYLTKEEFEELKNNTYIERFELRDECDNSYI
                     YTFYTNDKCNDIKFIKSQFIVTLIKIGFLCECGGVFRQKKIVDEYDYGYNAIYKCDSC
                     GKELDKEVENYD"
     gene            56283..57293
                     /locus_tag="PC512_000612"
     CDS             56283..57293
                     /locus_tag="PC512_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HDF2440385.1"
                     /translation="MHEDKNDIFESIDTEDFDNKTEEECLELVRKNGLNLIYIKNQTE
                     EICLEAVRQNCNAIKCVQNQTEKICIEAVKQDWRMLEFVEEPTEEICMLAINQDGTAL
                     KYIENQTEELCLRAVEKNGAALEYVKEQTEEICIEAVRNSEFGLARVKNQTEKICMEA
                     VKHCSYNLKWVENQTEEICMEAVRQNGLDLKFVKNQTETICLRAVRQNGMALEFVKEQ
                     TVGICLKAVRQYGMALKFVKEQTEEICTEAIKQDKRALSFVKGDKEKYKALYDNNEPF
                     AKRYVRNVIEKENRALIKKGEENAKIKIAGKLYDRGMSFEDISDIVEIEISKLKVSLG
                     VF"
     gene            57404..57892
                     /locus_tag="PC512_000613"
     CDS             57404..57892
                     /locus_tag="PC512_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF2440386.1"
                     /translation="MKITVLYQTRSGNTERVAKLIEEGAKKVDGVDVKLMRLDNIDLD
                     YLNESKAVIFGTPTYLANTTWEVKKWFDEDSKKVNLAGKLGAVFATCDYICGGPDVAI
                     LTIVGHLMVKGMLVYSGGGSLGKPFIHLGHVHSIEGPELQDEKAIIFGERIATKAKEL
                     FA"
     gene            58068..59996
                     /locus_tag="PC512_000614"
     CDS             58068..59996
                     /locus_tag="PC512_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF2440387.1"
                     /translation="MVWHIEYEIFSAIIVIFLMVYFFRSKFIPTLQNKIYCALLIFSF
                     LFIISNILGSFCLNNIDKIPIFITFLLNQIYLLLLPIPAALVSFYVMAIIYQDIRYMK
                     KRLLFLSIPLIICIILSITNPFTHILFGLSKETGYIRGCGYVATFASFFFYAIYSAFL
                     SFKYRKAMHESKIWAIRGFLIVSIVAIILQAIFLQYLLTGTACACSLLLTYLSMQNRG
                     LIIDDLTGVLNRQSFIQELDLNINTEQSGFIITIALDDFKFMNETFGTKNGDIALKEV
                     GKYLIQIHDVNHVYRIGGDIFSIVVNSQLGIEPDDIIRKIEERFKKPWLVEEISFNLA
                     TSIAVVYYPENAETTEDVIVAIDFSIHEAKRSESRRVVYADASISEKIKKKHVIKNCL
                     KEALKNDGFEVYYQPIFSNSRGRFTSAEALLRLEHKELGFIPPDEFIPIAEQTGLINS
                     IGLVVFEKVCRFIASDEFEDLKLDNIAVNLSVVQCMQKNLADDLLYLMNKYNVSPTKF
                     KLEITETVAMGSFNIIKETMERLIDLGVKFALDDFGIAYSGVTNMLSLPFSVIKLDKS
                     LIWSMNEDSRHKLTVETIIALINKLNMKAVAEGVETIKCAEDLIAMECEYLQGYYFSK
                     PVPEDVFKNLLKENTFTS"
     gene            60173..60583
                     /locus_tag="PC512_000615"
     CDS             60173..60583
                     /locus_tag="PC512_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HDF2440388.1"
                     /translation="MNKKKILVPIDGTERSMHSLEFIKGIFKKDEVEVEIMNVKELVF
                     IDGISLAEEIKNSENLGRRILDKAAEIMGEYDVKVHFTFGYPGDEIIRKAKEDNVDFI
                     VMTKSTKKGLTRMIGSVTASVVKQAKCIVMIVPE"
     gene            60605..60907
                     /locus_tag="PC512_000616"
     CDS             60605..60907
                     /locus_tag="PC512_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIBC"
                     /protein_id="HDF2440389.1"
                     /translation="MNKKIVAVCESERSLNSLKTAANDLGFDLVYEIQENDNIKNELS
                     IYDIEDASIVLFVTSDSIESIEKIDRFIDREFYEVDPKYIIEDAKSIVSEILIDLN"
     gene            complement(61124..61816)
                     /locus_tag="PC512_000617"
     CDS             complement(61124..61816)
                     /locus_tag="PC512_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HDF2440390.1"
                     /translation="MKSLNATEKIIDYIKLNILNGTFKINSKLPSERKIADLFNISRI
                     PVRNAINILCKEGILRAVPYSSPIVEGFKKVDLFDDGEIYKNHNIQEFYVESLRARQL
                     IESEATKLAILNATSKELQKIKYTYLKSIEELDKVSHGLIEECYDADLQFHKEIILAS
                     HNPIFIKYYELIPKTVSSNQYFGFKYRNSLKDMISHHNKIMIAFDSKDSYLGYTSMYN
                     HLEDVIQLFQHD"
     gene            complement(61842..63029)
                     /locus_tag="PC512_000618"
     CDS             complement(61842..63029)
                     /locus_tag="PC512_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2440391.1"
                     /translation="MKKISNQKLLLLSIVTFFWFSQYVYIPFQNPYLSACNVSTNMIG
                     IIIGAYGISQCLLRLPVGVFADSINKHKIFILSGIFFAGLASLIRVFSPGGNGFLIAN
                     ILSGISSSTWISYMVHYTNFFSTEHQQKATSTIILVNNLGMLIGFVMSTLFYEKLGMT
                     ALCIMSVLSSVIGTILALNIKNHNSKKIPEKISIKKYLSICKDKRLVFFSFMALIQQG
                     IQMSTTMSFTTQILKNLGSSSTLIGLSSIFYMVCAVASSGFASTKFCTKYGPKFWIPL
                     VFILVSAYCFLVPTIKNINIIFVLQVLPGISTGILLSYLTSESMKNVPKHQKSTAMGF
                     FQAIYAIGMSVFPMIVGKISEYTSIQYGYFILAIIAILASILSYTYYKKVDLTLNYDI
                     IQS"
     gene            63365..65242
                     /locus_tag="PC512_000619"
     CDS             63365..65242
                     /locus_tag="PC512_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2440392.1"
                     /translation="MDYKNIAQEILLNVGGKENVNEVTHCMTRLRFKVKSASKVNKDK
                     LSKTEGVITVVESMGQIQVVIGNKVKKVYDEVIKIVPQSNNVGKKNESQEKQGIINSI
                     LSAVAGIFTPTIPAIAGVGMIKGILSVLAMYYMNKNGVDIKETQSYIILNAMADSIFY
                     FMPIILGYTAAKVFNANKIISMVLGATLCYPTFTALMAGEESVRFLGLAVTKATYTSS
                     VIPIIIAIWALSYVEKVLEKYIPEVIKIIMVPTLSLVVMLPATLFLFGPIGIYIGNVI
                     NFSYKYIYELSPALCGAFVGGLWCVLVIFGAHRALLPIGISDVAQTGRQNLLAFAGAA
                     NFSQAGAALGVFFKTKNQGLKTISMSATITALFGITEPAIYGANLRLKKPMVCAVICG
                     AFGGAIMGMGGAYGNAFANQGVLTIPVYAEAGALGFLSYLGGCAIAFFGSAISTYLVG
                     FEDLEESSNKENSSIKVETKDGVIDITSPVEGECIELSEVKDDVFASKAMGEGIAVLP
                     TKGVITAPTDCEVASLFPTLHAIGLKLDNGAEMLIHVGINTVELNGKYFTKHVNQGDL
                     VKKGDKLISFDIDKIKKVGYDVTTPVIVNNTFDFGQVVSCKSSYVSTNDNIISLVLAG
                     N"
     gene            65552..66958
                     /locus_tag="PC512_000620"
     CDS             65552..66958
                     /locus_tag="PC512_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDF2440393.1"
                     /translation="MNTGFPKDFLWGASSSAFQVEGAWDKDNKGKTVADYNSFKKSHL
                     QADTKVASDFYHNYEEDIELMKELGMKTYRFSISWARIIPDGEGEINQKGLDFYNKII
                     DKLIECDIEPFVTLYHFDLPFKLVEKYNGWESRETVYAFERFAKICFKHFGDRVKYWQ
                     PHNEQNLIVRVEERINIYDETDSWKIDKMRAQMDYNLCLAHALAVNACHEMIKESKIG
                     AAVSSSVTYPLTSKPEDIYAARMNDNFKVYYMLDMHHYGEYPGYYMKYLEKRNIVPHM
                     EDGDKEILKKAKMDFIAVNYYRTNCAEALPEDSQHPFGLREGTVDFSMYGLFKMSMNP
                     NLEASEYGAAIDPSGLRVALNEYWQRYHLPVIITENGLGAKDILEDGKIHDDYRIDYL
                     RSHINACKLAIEDGVEMIGYCPWSFTDLLSSSQGFNKRYGLVYINRTDHEILDLKRIK
                     KDSFYWYKEVIENNGIVK"
     gene            66986..67834
                     /locus_tag="PC512_000621"
     CDS             66986..67834
                     /locus_tag="PC512_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF2440394.1"
                     /translation="MYITKVLNNSLLLAKDDNDEEIILMGKGIGHNYKAGSELNEKDI
                     EKIFVLHDENIKKSIIQLATEIDAEYFGIAQMIIAYGIEKYNLKLMNHIYLALTDHIA
                     FAVRRFKEGIMIENHYLFEIKEFNPKEYDIGKYAITVFKEVLGLDLPEEEIGNIAGHF
                     INAQQDNPYSDRNKRSAKIVNAILQIVHYHFSIVYNKESFYYRRFVMHLKAFSQRFLA
                     NEPSREKIDFIYEQVQKNCKEEYECVKKVGAYMYKEYSRELPRQEELYLMIHIHKILG
                     ELCENS"
     gene            68336..69028
                     /locus_tag="PC512_000622"
     CDS             68336..69028
                     /locus_tag="PC512_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003020373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2440395.1"
                     /translation="MNKVLIIDDDKDLCILLKKSISIEQIEANYCHSGRDGLVELSKQ
                     DYQLVVLDVMMPGMDGFETMEQIRKYSSIPILMLTSKSDNYSKVHGLRAGADDYLTKP
                     FEITEFTARVLSLIRRYTRFNPKNEEPQQLSFKGLLIDLDQHTVTTNGEPMLLPPKEF
                     GVLLYCARHQGKILTKQQIYEAVWGEPYVYDDSNIMAIISRLRKKIELDPSSPIYLQT
                     IKGIGYQFNTEV"
     gene            69025..69960
                     /locus_tag="PC512_000623"
     CDS             69025..69960
                     /locus_tag="PC512_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2440396.1"
                     /translation="MKMDEQTIILFLLLLSIGLLFLSIFAFSKLGHIHKRLKDIEEIL
                     ADVQIGDENRKILIKPCDVMAPLVYQLNEIVYDYENKLLSLKKSDKASKQLMTSLSHD
                     VRTPLTTLIGYLDAVHSGIVIEQEREEYLEIARRRAYDLKDYIDVLFDWFRLNSDEFT
                     LSIESVEIAELSRNILKDWIPIFHEKKLNFEIDIPENRLMVNLDPDGYSRVVNNLVQN
                     VLAHSKARQIKITMSEDSRMVLLRVEDDGVGIARENLPHIFERLYKCDKGRSEKGSGL
                     GLSIVSQMVERMGGQVSVESEIGKYTVFTVSLPLI"
     gene            70108..71031
                     /locus_tag="PC512_000624"
     CDS             70108..71031
                     /locus_tag="PC512_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013273760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2440397.1"
                     /translation="MNNLIIETKNLTKQYGAQKSVSNLNIHVQKGRIYGLLGRNGAGK
                     TTTMKMLLGLTKPTTGEIKIFGQDIHNNEKKLLPRIGCLIESPGFYPNLTGTENLKIF
                     ARLRGIPKKNAVESALDVVGLPNNDKKLFSQYSLGMKQRLAIALAIMHDPQLLILDEP
                     INGLDPIGIAEVRTFIRDLCTERGKTILISSHILSEIALLADDIGIIDHGILLEEESL
                     AQLEEKNSKYIHFAVSDAAQAARLLETQLNLKNFKVADNYNIMLYDTDVSVAEINRAF
                     ILNNIEVSESHLCEDTLEDYFKKVTGGEGIA"
     gene            71015..71785
                     /locus_tag="PC512_000625"
     CDS             71015..71785
                     /locus_tag="PC512_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2440398.1"
                     /translation="MKELLDIISCEFSKLKRLKFILISILGACLFPIPATILIAKDNL
                     PFEQLFKLVVNFGYFLLLPIVLSIVASQLFFIERDNDVLKNLATVPVPKGKLALAKLA
                     VLLFISLFYSVAGLGATIIGGFIVGIVEGVAVKLGMSIAFGIMFFVTVLPVVVLIVYF
                     NRSYIFSIILSFVYAIFNFSISLNIINFEPNNPLLSVLPAPVIMRWWMAFWGDPTGEY
                     TVLRQPYLLSTPACVGILCLITIIAVLLICMIYKKQEN"
     gene            71795..72577
                     /locus_tag="PC512_000626"
     CDS             71795..72577
                     /locus_tag="PC512_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2440399.1"
                     /translation="MLDIITTEFQKIKRYNILWIGVVAVLFSALLAVFQVVSSHGSDP
                     LTYESFANGVIWNNFSLSFPFGITLIGGYLINREYTDQTLKNILTVPISLRKLLVGKL
                     IAVGGITVLLSLFSFLCTFILGLLFCNINISVILVVKSLVQILSVNLYCYVAVLPIIA
                     YFGRKQNAFLTGVGIAFVYGFCGVFVAGRNLTDFYPITAGLGLVGYNNGAGTVYQPLI
                     GAMTLIVILILTTILLVFTPNYDKVMTISKKKGIKHKKYSHK"
     gene            72954..73490
                     /locus_tag="PC512_000627"
     CDS             72954..73490
                     /locus_tag="PC512_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin family protein"
                     /protein_id="HDF2440400.1"
                     /translation="MNLKGTKTEKNLMAGFAGESEARNKYTYYASKARKEGYNQIAAI
                     FEETANNEKEHAKLWFKLLHDGMPSTEENLKDAAAGENYEWTDMYAKFAKEAREEGFD
                     KIAYLFEAVGKIEKEHEERYLKLLENLNEGKIFKRDEEVVWQCQNCGHVYVGTEAPEK
                     CPVCDHPKAYFNIKAENY"
     gene            73522..73911
                     /locus_tag="PC512_000628"
     CDS             73522..73911
                     /locus_tag="PC512_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HDF2440401.1"
                     /translation="MKFSKQRELILNEILNNPVHPTADYLYENLKKDNPNLSLGTVYR
                     NLAQLTEHGFIRKVSIPGYPDRFDGRIDNHYHIICEVCGEVYDLESEVLNNLQELISE
                     ETDIKITSYNISFKGICNNCKRCSQVG"
     gene            73948..74334
                     /locus_tag="PC512_000629"
     CDS             73948..74334
                     /locus_tag="PC512_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="desulfoferrodoxin"
                     /protein_id="HDF2440402.1"
                     /translation="MCSEQKFFICETCGNLVGMIQSGGVPIFCCGKPMKELVPNTTDA
                     AVEKHVPVIEVDGNNVTVKVSSTTHPMTKEHHIAWVYLMTEQGGQRKCLAVDGEPVVK
                     FALNDDDKVISAYAYCNLHGLWKAEL"
     gene            74461..75903
                     /locus_tag="PC512_000630"
     CDS             74461..75903
                     /locus_tag="PC512_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HDF2440403.1"
                     /translation="MSIYKCSVCGYIYDESKNDKTWDELSEDWECPVCTKGRSYFGKI
                     STVYYEEDEKIAEDIVEDESKLNTEKEGDLNYLSTYLRRDDEVEKHMDIIHEMAVTGK
                     SIIEPMRTKLPVISWDDILIMGAQLNPLPLNEHDEVNTTTIIGKKAKKPMIIENPVYI
                     SHMSFGALSKELKIALAKGAAQNKTAMCSGEGGILPEEKEASYKYIFEYVPNKYSVTE
                     ENLKNSDAIEIKIGQGTKPGMGGHLPGEKVTEEIAKVRNKPVGQDVISPSCFEEIQSK
                     EDLKKLVDELREVSEGRPIGVKISAGHIEKDMEFIAYAKPDFVTIDGRGGATGASPKL
                     LKDATSIPTIFALYRARKYIDTHGLDIDLVITGGLRISTDFAKAIAMGADAVAIASSA
                     LMAAACQQYRICGSGKCPVGVATQDEELRKRLHIENSANRVANFLNVSLEELKTFARI
                     SGHKDIHDLSVDDLYTVNSEISNYTNIQHV"
     gene            76200..77015
                     /locus_tag="PC512_000631"
     CDS             76200..77015
                     /locus_tag="PC512_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2440404.1"
                     /translation="MERLKIQVLVDNNTYIDRYFVGEPAVSYYIEIDGNRILFDSGYS
                     DVFISNAEKLNIDLGNLTHVVFSHGHNDHTRGIQFLENRYDLSTVELISHPNCFIPRK
                     HGEKSIGAPFSAEEIKNIFMYNPKDKPFNLSKNCVFLGEIPSINDFEKRAKIGKCKIG
                     DLWEDDYVLDDSAIVCKTDKGIFIVTGCSHSGICNIVEYAKKVCGDDRVIGILGGFHL
                     FELNNRLDSTIQYLDKEEIRMLYPCHCVSFKVKAKMNEILNINEVGVGLTISI"
BASE COUNT        29073 a         9099 c        13932 g        25176 t
ORIGIN      
        1 tgacattcta attttgtagt gtaatcgtat tttttattaa ttcttacaaa atcaatgaaa
       61 ataagtatat ccattttaaa gtacataaat ttaaaaatcc agaaaaatat acttaaatta
      121 tgtaagtaaa agaggggttg aatcagttga aaatgtaata ttagcaaata gtacatcaat
      181 cctatatacc ctgtaagcaa ctctattttc atgtactaaa aatgtaccta ttttattaac
      241 tgaaaagaat aaattaaatg taagtacata agaagataga aaaaattaaa aacaaaaaat
      301 atttatataa ataaatataa aaaatgatat aatccctatt aaaaaattta tagatgatga
      361 agaaatatca aaatcttata ttataggaag agacacttct ttgccaaaat ctatagaaaa
      421 acaataccaa atccaaagag aataggcgga gaaaaaaata aaataaattc aagagtaata
      481 gaaaagtttt atagaataaa gaactgataa ctctttatat aacgaaaaat agaattttaa
      541 gagaaaatga tttaataact gatttaacat ggtgttttag caggtaaaaa taaatcacca
      601 gtaatgatta tagaaaaatt actttatgaa tctcaaaaaa cttagttaag agtaagagat
      661 ttgataagat aactaaagtt ggggaaatgt gtttgatgag acaaaaaatt agtaaaatag
      721 tataatctaa ataaggatat tttgttgatt aaactacact aatagtaata ttgtaggggg
      781 aaaagatgag agaagaatcg aactctttaa gtttagacca tatagaaatt ttctttgaac
      841 ttttatctca aagtacagaa gattatatat ttttttggga tataaatagg aataaattta
      901 aaatttcttc agcaattttt gatgaattta acttaagtaa agagatagaa tctgatttgg
      961 tcaattgttg gagtaaaatt gtttatccag atgatgttca aatatggaaa gatgatatac
     1021 aagaattact acatggaaaa aaaggtgagc acaatttaga atataggttg attaataaat
     1081 ataaagaaat agtatggatt tcttgtagag gtaaagttta tgtgtcggat gacccaaaaa
     1141 ctatatttct agtcgggaga ataaagaata ttggtgaaaa aaataaattt gattctatca
     1201 caggaacgtg gaatagagaa caatttgaac ataaaatgaa ttatcttata aaagagaaaa
     1261 tttataaaaa tggtgctatg tttattatgg atattgataa ttttaaaaat ataaatgaaa
     1321 aatatggaca ttcttatggt gacaaagtgt tgcgtgcaat tgctactgaa gtactggaat
     1381 atcttccaaa agatgtaaga ttgtataggt tagatggaga tgaatttgca tttttttacc
     1441 ctatgtgtac taaagaaact atagagaaaa tatatgaaaa gatacagatg tatacaaata
     1501 ctcagcatga aattgaatca agtaagtact attgcacagt gactgcaggc gttgctatgt
     1561 atccagaaga tggagataat tatttagatt tatttaaaca tgctgatatt gcattggata
     1621 tagcaaaaat tagtggtaaa aatagaatta agtttttttc acaagagctc tatgaaaata
     1681 aactaaaggt aatttcaatg caacaaaaac taagagagtg cgttgaaaat aattttaatg
     1741 actttgagct gttttttcaa ccccaggtaa atgctgttac aaaagaggta ataggggcag
     1801 aggtactttt aagatggcat tcgagtactt atggagaagt atctcctgtt gaatttatac
     1861 caatactaga acagagtaat ttaattatac cagttgggaa gtggattata aaagaagctg
     1921 taaaacagtg taaagaatgg cataaaataa atccagactt taaaatatct gtaaatgtat
     1981 cgtatattca gttaaaggaa gattttttta gagattttat agtagaatgt ttagtagagt
     2041 atcaattaag acctgaattt ttaattttgg aattaacaga gaattgttgg ataccagata
     2101 taaatttact aaatgataaa tttattagtt taaagggtat aggagtatat attgcaatag
     2161 atgactttgg tacaggatat tcatctttaa attaccttaa agaactgtct gttaatataa
     2221 taaaaattga aagaagtttt gttaagaata ttacatataa tagttatgaa tatacttttc
     2281 ttgaatatat tattaaatta gctcatatta taaatttaaa agtttgtgtt gagggaatag
     2341 agtcttatga agagtatgat atagtaaaaa gcttaggggt agatattatt cagggttttt
     2401 tatttggaag acctgtaagt gcctctgaat tttataaatt tcagctatca aagtgatgta
     2461 tataaaatga gatatatagt atataaaaat agggcaaagt ggaagttttg aagtttatta
     2521 aaaatttaca ctttacccta ttttgttatg tcttctataa aggattaata tactacacta
     2581 actattatat actttcactc caaatttaga gattatttca ctagcttttt ggacatcttc
     2641 cttagtggca tcaggaacat cttttagttc ataatcgata cctaaacttt cccatttgtg
     2701 tattcccata gaatggtatg gtagcaattc aaatctttct acatttttca atgtagctac
     2761 aaattgacct agtttttcta aattatctat atcatcagta atgccaggaa ctaaaacatg
     2821 tcttatccat acaggaatat ttcttgattc taagtgtcta gcaagtttta atgccttatc
     2881 cataccaaca ccagtcaaat caatagattt ttcctcaacc atatgtttta aatcaagtaa
     2941 aaccaaatca gtattatcta aaactgggtc tatagtttct atatctacaa atccagatgt
     3001 atccaagcaa gtgtgtatat cattttcttt tgctttttta aataattcac ttaaaaattc
     3061 tggttgaaga gtggattcac caccagaggc agttatacct ccaccagaaa acttcataaa
     3121 agaagtatac ttaagagcat ccgttattat ttcatcaact gtgtattctt ttcctgattt
     3181 aatatcccat gtatccctgt tatgacagta tttgcatcta agaggacacc cctgaaaaaa
     3241 taatatatat cttattcctg gtccatctac agtaccaaac gtttctatag aatgtatctt
     3301 tcccttaatc atagagttca cctcacaata tattttaata accttatcaa tagttataat
     3361 atttctctaa aaaaggccat cttataccag aaataattca aatataagat agccttttat
     3421 ttttattttt tacacagtag taatcttagt taaagtataa aaatttaaag actaagccat
     3481 tttaccgtgg aatgttctgt ttataacatc taattgttgc tctttagtta attttatgaa
     3541 gttaactgca tatccagata ctcttatagt taattgtgga tattcttctg gatgttccat
     3601 agcatcttct aaagtagctc tatcaaatac atttacattt aagtgatgag cattttgagc
     3661 gaagtatcca tccatcattg cagaaagatt gtttattctt tcagtcatat cttttcctaa
     3721 agcagcaggt actatagaga aagtattaga tataccatct tgagcatgtt catatggtaa
     3781 tttagcaact gaagataatg aagctaaagc accattagta tctctaccat gcattgggtt
     3841 agcaccagga gcaaatggag caccagctct tctaccatct ggtgtattac cagttttctt
     3901 accataaaca acatttgaag ttattgtaag tatagattga gtaggataag aatttctata
     3961 agttttattc tttcttattt tattcataaa gctttcaact aactctacag ctatactatc
     4021 aactctatca tcattatttc cgtattttgg ataatctcct tctatttcaa aatcaacagc
     4081 tattccttgt tcatttctaa tagttttaac cttagcatgt tttatagcag ataatgagtc
     4141 tgcacaaact gataatccag ccataccaca agccatagtt ctaaatatat ctctatcatg
     4201 taatgccatt tctaatgctt cataagaata tttatcatgc atataatgta ttacatttaa
     4261 agtatttaca tataatgttg ctaaccaatc agtgaatggt tcaaatttac tcataacttc
     4321 atcataatct aagtactcag aagttatagg ttcaaatctt ggtccaactt gaacaccaga
     4381 tttctcatct acaccaccat ttatagcgta taataaagtt ttagctaagt taactctagc
     4441 tccaaagaac tgcatttgtt taccaattct cattgcagat acacaacaag ctataccata
     4501 gtcatctccc cagtatgctc tcattaaatc atcattttca tactgtactg aacttgtatc
     4561 tatagatact ttagaacaga aatctttgaa tccttgaggt aatttagttg accatagaac
     4621 tgttaagttt ggttctggag aaggccctaa tgtatataga gtatttaaca ttctaaatga
     4681 gtttttagta actaatgttc taccatctat tcccatacct cctatacact cagttaccca
     4741 agttgggtct ccagagaata agttattgta atcaggagtt cttaggaact taaccattct
     4801 taatttcata acaaaatggt ccatatactc ttgtaattct tcttctgtta cgattccagc
     4861 ttttaaatct ctttcaaagt atatatctaa gaaagtagat gttctaccta aagacattgc
     4921 agcaccattt tggtctttaa cagcacctaa ataaccaaag tataaccatt gtacagcttc
     4981 ttttgagtta gttgctggtt ttgatatatc aaatccataa gattcagcca tttttttaag
     5041 ttcatttaaa gctgatattt gctcagttat ttcttctctt aatctgataa cttcctcatc
     5101 catgcaagaa acttctaatg atttcttttg ctcattttta tcttctatta aagcatcaac
     5161 accatataga gcaactcttc tgtagtcacc aattattcta cctctaccat aagcatctgg
     5221 aagacctgtt attataccag attttctagc agctctcatt tctggagtat aaacatcaaa
     5281 aactccttgg ttgtgtgttt ttctgtattt agtaaatata tcttttattt ctgggtctaa
     5341 ttcatatcca aaagcttcgc atgaattttc aaccatcttt ataccaccat atggcatgac
     5401 agctcttttt aaaggggcat ccgtttgtaa cccaactatt gtttctaatt ctttatctaa
     5461 atatcctgga gcatatgcag ctattccaga aacagttttt gtatcaacat ctaaagtacc
     5521 accattttct ctttcttttt taaataggac cattgcttcg tcccataatt ttttagtatt
     5581 ttcagtagca ccagctaaga aagagtcatt tccctcatat ggagaatagt ttaattgtat
     5641 aaactctcta acatttattt ctttagtcca tcttcctgtt ttaaatcctt gccatgcatt
     5701 cattaagtat ttcctcctta gatttaaatg ataaataata ctattaaaat taatttttat
     5761 atacttaatt tattttatat atttttttaa aaatatattt tctaatataa taatatcata
     5821 ttattcgtat cctgtataca taaaaaataa aaaattgtcg ctttaaagta taaaacagat
     5881 tatatgttaa taatgtggtg aaattatacc catatataaa taaaataaaa caaataaata
     5941 gctaattaag gagaaaatat tttttatttt ttgtttagga taaataaatt ttattatgga
     6001 aaaaagaaaa agcatacatc ttcacaaatt gaatatttat ttaatagggg gaggtgatag
     6061 attgtttatc acagtggtat tatttttagt aggtttccta ttaattacta aaggcgcaga
     6121 tatctttata aattgcactg tagagatagg taaaaaaacg aatatatcag aaattatact
     6181 tggagctact atagttagtt ttgcaacaac attacctgaa tttacagtgt ctctacttgc
     6241 ttctattgat ggtcatacta ctatgagttt aggaaatgca gttggttcta taatatgtaa
     6301 tacaggatta gcattagggt tggttgtttt tataagtcca tttaatgtag ataaaaaaat
     6361 gtttttttct aagtctttac tattaatagt atccgttata gttttaattt tattgagttt
     6421 agatggagtt ataacaagag gtgattcatt attacttata ataatattaa tcttttatat
     6481 ggttaataat tatagaagtg tcgttggaaa atctgatact aaaaatagaa atattaaaaa
     6541 taacactatt aaagacatat ctactaaaaa agggaaaaat tatagaggtt tttccgtatt
     6601 agaaattgta aaaatactat tactttttgc tacaggattg ataatgatga taataggttc
     6661 acaaatcctt atagagagtg gagtaataat agctagtttt ttaaatatac ctcaaggtat
     6721 agtaagttta actataatag cacttggaac ttctctgcca gagatagttt cgtcgattac
     6781 tgctataaga aaaaatcatc atgaaatatc agtaggaaat attttgggtg caaacatatt
     6841 gaatatagta tcagtaatag ctgtatcagc aataccaaat aacataccaa tactatctca
     6901 aaatagacaa ttggatatac cattcatgat attattatta ttaatagtaa taataccaac
     6961 acttaaatct aatagactta gtagaataca aggtatattg atgttattca catattttct
     7021 gtacatatca attttgtatt tcatgtatat tatttaacta tactgtttaa aatattaatt
     7081 gcagaatatc ctaaaaaagt atataatgga taggttaaga ttaattgata acggagagga
     7141 ataatatatg aatataacaa agtttgaaga tttaccaata agtgagggaa taaaaaaagc
     7201 tatagctgaa atggggtttg aagaaccatc tcctatacaa gcacagtcta tacctgcgat
     7261 tttgtcaggt aaagacgtta taggacaagc tcaaactggt acgggaaaaa cagctgcttt
     7321 tagtatccct atactagaaa caatagaccc aaataataga agtttacaag ctgtagtgct
     7381 ttgtccaaca agagaactgg caatacaagt atcaacagaa ataagaaagt tagctaagta
     7441 ttcgcacgga ataaagacat tacctatata tggtggtcag ccaatagata gacaaataaa
     7501 atctctaaag agtggtgtgc aagttgtaat aggtacacca ggacgtacaa tagaccatat
     7561 caatcgtaaa acattaaaga tggataatgt aaaaatgatt atattagatg aagcagatga
     7621 aatgctagat atgggattta gagaagatat agaaatgatt ttaagtaaga ttccagaaga
     7681 aagacaaaca actttctttt cagctactat gccaagagga attttggaat taactaagag
     7741 atatcaaaaa gacccagagc atataaaagt tgttagaaaa gaacttacag tttcaaatac
     7801 aaagcaatac tatatagaaa ctaggtcatc aaataaatta gaagtattat gtagattagt
     7861 agatgtatat gaccctaaac tatctgttgt tttctgtaat actaagagaa aagcagacga
     7921 attggtagga gatttacaag caagaggata ttttgcagat gcattacatg gtgacttaaa
     7981 acagactcaa agagatatag taatggataa gtttagaaat ggtacaatag atatacttgt
     8041 tgctactgat gttgcagcta gaggtataga tgttgatgat gttgaatgtg tattcaacta
     8101 tgacttacca caagatgaag agtattacgt tcatagaatt ggtagaactg gtcgtgctgg
     8161 tagagaaggt atgtcattta cttttgtatt tggaaaagaa atgagaaaga tgaaagatat
     8221 agaaagatat actaaatcta aactaataaa gcataatata ccaacaataa ctgatgttga
     8281 agagaaaaaa gtaggtactt tctttgcaca agttaaacaa actatagaag aaggtcactt
     8341 aactaaacaa ttacaatggt tagaaggttt ctgtaatgat gaagattatg caatggttga
     8401 tatagctgct gcacttgtaa aactatctct aggtgaagaa atgaaagaag aaataataga
     8461 agaaaaacct agaagagagc gtggagatag aaaaggtggt actggagcta aagatggtat
     8521 gattagatta tttatcaata ttggtagaaa tcaaagagta caagcaaaag atatagttgg
     8581 tgccatagct ggagaagttg gaataccagg taaagtagta ggtactatag atatatatga
     8641 taagtatact tttgttgaaa tacctaaaaa agatgcaaaa acagtaattg aaaagatgaa
     8701 agatattaag ataaaaggta ataagattaa tatagaaaaa gcaaacaaga agaaaaaata
     8761 acgtatagta tacaaaacta taattagaaa atatataaaa taatatattg gatatttaaa
     8821 aagcctgatg tgttttcaaa acagatagta gataatctgt aagagttaac agcataaggc
     8881 ttttcttgtt ttatatgatg ttataatttt ccagattgtt gtgaaaaatg tatattagtt
     8941 cctttttttc aaatctgatt tgaaaaagag aatattaatt atctatatag tttagattat
     9001 aataaaaaat gtaagataac aaaggggaga aaaagatgtc aatgacttat atggacccta
     9061 gggttttttt gattttagaa atggtgttag aagaagacac aaatactcta gaacaatttt
     9121 caaatgtttt gggtgttagt actaggacta tcagaaacta tataaaccag attaatcgag
     9181 aattaaaagg tggtattgct aaaatagtta aaaatgaaaa aggtacatat agtataagaa
     9241 ttgaggatga aagtaaatta attgagattg taaattttaa tagaggaaag ctatcaaatt
     9301 ttataaattt aaattcacct gatgaaagaa taaattatgt tcttgatatt ttaactatga
     9361 ccaacaatcc aattaccata gatgatttgg ctgaagagat atgtatagga agaacaacat
     9421 taataaagga tttaaaaaaa gcagacagaa ttttagctga atatgattta gaattaaaaa
     9481 ggaagccaaa tataggtatg attttagttg gtgaagaaat ggatataaga ttattaatcc
     9541 ttgatagatt gtatgaaaat tatattgatg tcttggaaaa cgttaatcag ataaatttag
     9601 ttaaagatta tgatattgaa tgtcttagag atgaattaaa aaagttattt aaaaaagaag
     9661 aactctacat aacagaacag gtcttgagag atgttgaaag atatataatc atgtctgtct
     9721 taagaaatct aaatgggtac aaatttgaaa agatagataa gagatttgaa gtgataagat
     9781 gttcagatga atatacttta ggattaaagc tcaaagcttt attggaaaag atatttaata
     9841 tagttttaaa tgaaaaagaa accatatttt tgacaatgcc attaataggt agaaaagctc
     9901 ctagtacaaa attagcactt agcagtataa agataaatga tagcgtaaag gaagttgtag
     9961 atgaagtaac tagtttttta ttagagacct cagggattga ttttaaagaa gataaaaagc
    10021 ttatagaaaa tttggaatat cacttgtatt ttgcacttaa tagaatgaga ttcaacataa
    10081 gggtaaaaaa tcctctttta caagaaataa aggaaagata tacatttcca tatagtgttg
    10141 caaagatagc tgcaatgata attgaggaaa agtttgactt gaaaatatgt gaccacgaaa
    10201 taggatatat agcattacat tttggaagtt attttgaaaa aaattcaaga aaagttctaa
    10261 atgtaaatag ggtagctgtt gtttgtggaa caggtcttgg gactgcacaa cttattagaa
    10321 taaagatagg aaaaatactt ggagaaagtg tagaagtaaa tactttttct gatatagaag
    10381 ctaaagctaa tttagattta ttaaagtatt atgatttagt atttacaaca gtagatttca
    10441 aaacagactt agatgttcca atttttagag taaatgcgtt atttaatgaa gaaagtataa
    10501 agaaagagat agaaaatgca atacttttga aaaatagtat aaatcttaag tctataaaaa
    10561 agattgaaaa aaatatccct tttataggta aattaattga agaggataag ttctttatat
    10621 tgaataagag tacgtttatg gaaaatttag aagatatgtt agaaaaatta gttcataaag
    10681 gaattattga tatagagttc aaaaaaaagg tattaaaaag agaaaagaaa tcttcaacag
    10741 cattagataa ttatatagca ttgcctcact cagttaatac taatggggaa aatctttatc
    10801 tggcatttgg aatattagaa aaaccagtga tttgggatac aaaggaaatt agaataataa
    10861 tattgatgat aattccagat aagaatgtag atagcacaga cctgataata aaaagttatg
    10921 aagaagtact tgaagtaggg agagataaaa agatggtaga agaacttgct aaggtaaaat
    10981 catttgatga attttataaa ataattacca agaggaggta ataatatgga cccagtaatt
    11041 tttattatag catcacttat tacagtgtat ttattaaata tttttcttgg atacttacag
    11101 cttaaagatt ttaataaaaa ttatattgaa ctaaaaagaa aaggaagagt ggcaattggc
    11161 agaaaaaaag gaagaatttc atcaggtaca attgtgttga tacttataaa tgatgatggt
    11221 gtgattgtcg agactagaaa aatgcaaggt gttacagtat tggcaagagt aaagtcattt
    11281 gaaggtttgg taggaaagag cttagagtat atagaaaaat cagatttaac tgtttacaat
    11341 aaactactta aaaaagcaat actagatgca gtcaaacagt acataacatt tgagaaaaat
    11401 aaatgtgaag atacaaataa tctgagtact gatgaagagt gtaggatgga agtagtttaa
    11461 aaaaatatat ttataaggag gagttaatat gacgcaattt tttcaagtat tagcaagtgg
    11521 tgcagatagt tttatgaatt tatttagggc aggtgggcaa caatttgtag gttttgtaac
    11581 agatatagta ccacttttag tagcattatt agttacaatg aatgcaatta tcaactttat
    11641 tggtacagat agagtcgaga gacttgcaaa aaaatgttct gcaaatatat ttactagata
    11701 tttgatatta ccagtccttg gtacatttgt atttgcaaac ccaatgacac tatcattagg
    11761 aagattcttg ccagaaaagt ttaaacctag ttactttgca gcagcaagct tttcatgcca
    11821 tacaatgaat ggattattcc cacatatcaa tccaggtgaa ctatttatat atctaggaat
    11881 tgcaaatggt ataacaactt tgggattctc aacagcagat ttagcagtta gatatttgtt
    11941 agtgggtata gttgcaaact ttattaaagg tgtagttact gactatacaa caaaatttgt
    12001 agagaaacaa caaggaatag cattaaattc agatataaag attggataat tactttaagg
    12061 tataaataaa tttttcaaat aaaaagatag tgtatagagg aggataaatt atatggcatt
    12121 taacaaagtt aaaatagtaa aaggttctgg aggatggggt ggaccattga taatagaacc
    12181 aacagaaaag aagaataagg tagtatatgt gactggggga gcaaagccag aaactgcagt
    12241 aaaaatagct gaacttacag gatgtgagtt aatagatgga ttttcacagg gtgttaaaga
    12301 tgatgaaatc gcatgtgtaa taataaattg tggtggaaca ttgagatgtg gtatatatcc
    12361 tcaaaagaaa ataccgacta taaatataat gaaaacagga aaaagtggac cattagcaat
    12421 gtttataaaa gaagatatat atgtttcagg ggtaaaacca acaaatgtag agcagttata
    12481 attgaggtag taggagggaa gaaatatggc ttatgatact aaaaagaaga taagtgagca
    12541 gagtcaagga attgttgcaa aaataggtat agcactagga aatgtgacaa gtactctttt
    12601 tcaagctggt agggatacta tagatacatt aatacatact atactgcctt ttatggcttt
    12661 cgttgcagtc ctaataggta taataaatca atcgggtata ggaaattggg tagccaattt
    12721 acttactcca ttaatcggaa atgttggagg tttagttgtc ttatcaataa tatgttcatt
    12781 tccgttgttg tctccgtttc ttggaccagg agctgttata gctcagatag tgggggtatt
    12841 ggttggtaca gaaataggaa aaggaaatat tccaccaagt ttagcattac cagcattgtt
    12901 tgcaataaac tcacaagcag cttgtgactt tataccagta ggtcttggtc ttgcagaagc
    12961 tgaacctgat acagttcaag taggagttcc gtcagtttta tattctagat ttttaacagg
    13021 tgcaccaact gttctattag catggttagc aagctttggg ttatataaat agaagaatac
    13081 tttataaata attagagaga ggttcagttg atatggaatt aatatacagt actcaaataa
    13141 ataaaatagg agataatgca aatgaatttt tacaacataa tatgtttgta actttcaaag
    13201 ataatgctcc tcaagagtta gaaaattact gttatataca ttctgaaaat aatttagtaa
    13261 aagaaatact tacggatgat gtgctatcaa taaataatgt tgattacaaa attacttctg
    13321 ttggtgagtt agtaaaccaa aatctttcag aattaggtca tataacattt aagtttacag
    13381 gtgaaaaaga tggagcaatt ggaggaacct tatatcttga agaaaaagaa atagcaccta
    13441 ttggcgtagg tactatacta aaaataatta gaaaataaaa tttaaaacga atctaatcat
    13501 attataagta aattatagat aaaagtcaat ttaactaatc aagttaactt ttaatgtgat
    13561 aaaaaagggg aaatgaaaat gagaaaagtg gctttagtcg ttggaggagg aagaagttta
    13621 ggtgaatatt tatctaaaca tttagctaaa gtaggttatg atgttgctat tgcagattta
    13681 aatgaagaca acgcaaaaaa agtagctgaa gaaataaaaa ctgaatttgg ttgtaaatct
    13741 gtaggatata gttgtaatgc catagatgaa agacaggtta taagtactgt caaagctatt
    13801 gaaaatgatt ttgatagaat agatttatta gtgtacaatg caggagtggc tgtaagtaaa
    13861 aaaataactg attttggata caaagatttt aaatttattg tagacgtaaa tttaaatggg
    13921 tactttctat ttgcaagaga agtatctaaa gtcatgatag caaaaggtat tgagggtaga
    13981 ataatacaga taaattcaaa atcaggtaga gtgggaagca agcataattc aggatattca
    14041 gcaggtaaat ttgctggagt aggacttact caaagtttag cgctagattt ggcagaacat
    14101 aagataactg taaatgcact gatgctcggt aatttacttg attctgatat gtttgaaagt
    14161 ttaattcctc aatatgcagt aaaattggga atacctgaat cagaagtcaa gcaagtttat
    14221 atagataaag tacctttaaa aagagggtgt agatttatag atgttgcaaa tatgcttaca
    14281 ttttatgctt caaaggaagc tgaatactgc actggtcaat ctataaatat tactggtgga
    14341 caagttatgt aaggttttta tggagtgtct caagatgaac tctttagttc atgaggcact
    14401 tttttgtata aaattaaata tattttcagc atttaaacaa tgaaaaagag gtttatcttt
    14461 attttgagat agcctcattt ttgtaattaa aaaacatagt gtttaagtaa acatataaga
    14521 ttgttagttt tttaaaagag aattttttaa taatattata tttatgaagt atttttaaac
    14581 ttaatttgat aaaatatagc tatgttttat atactgtagt tttgaacata gaaagtttaa
    14641 taaattatag tatatatgtt aatttttaat aaggtaagaa agtagaaaga aggatatttt
    14701 atggatataa taaaaaaatt aagtcatggg tgtacattag attgtcatga ctgttgtaaa
    14761 ttcaatgttt atactaaagg aaataatgta gtaaaaattg aaggagataa aaatcatcct
    14821 tatacaaaag gttttatatg caaaaaaggg atggcccatt tagatagatt aaatcataaa
    14881 gatagaataa agactcctat gcttaaagtt gatggagtat ggaaagagat ttcttttgat
    14941 aaagctatag aaataatggc agaaaagctt acatactata aagaaaagta tacatcaaag
    15001 tctgtcatgc attatgacca atatggaagt gggtctgtgc taaaatacat aggagatata
    15061 ttttttaatt tttatggagg tgttagcaga cataagggtg gtccctgttg gagtgcaggg
    15121 atgcatgctc aaaaatatga ttttggagta gctaagagtc atgctataga agatatgtta
    15181 aatagtaaaa gtatatttgt ttggggaaaa aatccagcat atactacaat tcatactatg
    15241 caaataatta aaaaagctaa agaaaaaggg ataaagatag tagtgattga ccccatatat
    15301 acaaaaacag ctcaaatagc agataagtat gtacaagtaa atcctggaac agatggagct
    15361 ttagctatag ctatggcaaa aattatagtg gaagataaat tatatgatga agaatatata
    15421 aactcgtatg ttattggttt tgaagaatat aaaaaatatt tatcttcatt ggaattaagt
    15481 tttttaattg atgaatgtgg tgttaaagag aatgatataa gagagttagt ggatttatat
    15541 actaacaaat attcaagtat aaatgttgga tatgggcttc aaaaatataa aaatggtgga
    15601 aacacaataa gagcaataga tgctttaggt gctataactg gtcaaatagg atttagtggt
    15661 ggaggggtaa actatgctaa taaagtttat ccgagtgtta taaattctga cccttacaat
    15721 agccaatcat atggtgaaga tagggagttt tatgtaagta atatcagtaa atttatagaa
    15781 gaatctttaa aaaatacatc aaataaagta aattatgcat cagatgaact tgatatggca
    15841 ttacataaag taaattacat atcagatgaa cttgatacaa catcaaataa agtaaattat
    15901 gtatcagatg aacttgatat ggcattacat aaagtaaatt atgtgtcaga tgaacttgat
    15961 acaacatcaa ataaagtaaa ttatgtatca gatgaacttg atatggcatt acataaagta
    16021 aatggtgtat cagatgaact tgatatggca ttacataaag taaattgtgt atcagatgaa
    16081 cttgatatga catcaaataa agtaaattat gtatcagatg aacttgatat gacatcaaat
    16141 aaagtaaatt atgtattaga tgaacttgat ataacatcaa ataaaacaga ttatatatca
    16201 aatgaattgt ataatttatc taataagtca atcaaagata atattcctat aaagatggct
    16261 gtgataacta aaagtaatat gctgaatcaa ctgccagatt tagtagaatt ggagagggtg
    16321 ttttcaaaaa ttgaatttaa agtatgtttt gatatgttta taactgatac agttacttta
    16381 tgtgacatgt ttataccgtg tacaaataca ctggagagtg aagatataat ttatagctca
    16441 atgaccaatc catatataac ctataatgaa agagctgtaa agccagcaca taaattgatg
    16501 gatgaatatt acttctttat ggagctagct aaaaagatgg gattaaatga ttatcctttt
    16561 gtagaaaaga gaacttattt agaaaaagtg attgaaccac ttaagcgttt tgacaaaaat
    16621 ctggatatag aaaaacttaa aaacaattac tttactatac ataaccctgt tgcttgggaa
    16681 gataagaagt ttgagactcc atctggaaaa tacgagcttt attcagaaag tataaaaaac
    16741 ttgggaataa gtccaacacc tgtatatata agcaataaat ataaagaaat agaagataaa
    16801 aatatttctt ttagattatt aactaatcat catgcagata ctttatttag tcagcatttt
    16861 atggacaaaa aatctatagc tcaagcatat ataaatcaga gaatggctaa aaaagtaggt
    16921 attgaggaga aagatattgt gatattgagg tcaaaaaaag caaaaataaa tgtacaaata
    16981 aatatagatg atggagtagg taattatata gtaaaaatgt atgttggttg gtggaagaaa
    17041 catggaaatc ctaatagttt aacagacact ggtatatcag attttggggg tcaggtaaca
    17101 tataatgaaa gtatggtaga aataatacga caaaactagt taaatttcat tgaaggaata
    17161 aaaatataat tatagaattg attaaaagtt actattttta caaaactatt gaaggaggga
    17221 tttttgatgg taaattattc cttagaacat aagaatctat acatagaatt tatgtgctca
    17281 gaactagacc accatgtagc caatgaaata agggaagaaa tagataactt attaagtgta
    17341 aatcaagtaa aaaatgttgt atttaatttt gaaaatatta attttatgga ttcttcaggt
    17401 ataggcgtca tcataggtag atataaaaag atttctaatg aagggggacg agtttcagta
    17461 attaatataa gttcacgagt taagaagatt tttgatttat ctgggttaaa taaaattatt
    17521 ggcatttatg atacgtatga agaagctcta agttctttgt agggaggagt atgtgatgaa
    17581 taatattatg gaagttaaat tttcggcaat atctgaaaat gaaagtttag caagagttat
    17641 agtagcatcc tttgcagcta agttagaccc aacagtagat gagttagtag atataaaaac
    17701 tgctgtctct gaggctgtta cgaatgctat aatacatgga tatgaagaag acagttctaa
    17761 gtttgttttc ttaagatgtg agatagaagg aaatactata aagattatag ttgaagatga
    17821 agggtatgga atagaaaatg tggagaaggc aatggaacca ctttatacat caaaaccaga
    17881 acttgataga tcaggaatgg gattcacagt aatgaaaagc tttatggacg atgtagaggt
    17941 aagttctgta aaagataatg ggactagaat tgaaatgact aaaaaaataa atgtgcctaa
    18001 ataaagtcca aaagtgaggt tttattatgg aagtaactgt tgccagagaa gaaaaaaaac
    18061 ctcttcttag tcatgaagag actctagaac ttattgaaaa agttcaaaat ggagatgaag
    18121 aggcaaaaga aatattaata tcaagcaatt taggtctagt taggagcgtt gtatctagat
    18181 ttttaaatat aggatatgat agagaagatt tatttcagtt aggttctata ggcttaataa
    18241 aatcaatata taaatttgac ccaaaattta atgtaaaatt ctctacttat gcagtaccaa
    18301 tgattttagg tgaaataaag agatacttaa gagatgatgg tatgataaaa gtatcaaggt
    18361 cgttaaagca aatagctgta aaggcaaaga tggaaagtga agctttaact aaaaaattag
    18421 gtagagagcc gagtatagaa gaattagcta aagcaataga tgtagaaaaa gaagatttag
    18481 taatggctat ggaagctaat ttcaatgttg agtatttgca aggagttatt catgaagagg
    18541 aaggttctcc aatatgcctt attgataaaa taagcatgaa aggagaaagt gaagaagaaa
    18601 aagtagtgga taacatattg ttaaaagaca tacttggaag actggataag agagagcgtc
    18661 aaataatagt tctcagatac tttgaagaca tgactcaaag tgaaatagga gagatgctca
    18721 atatatcaca agttcaagta tctaggatag agaagaaagt attgtctaag ttaaaagaat
    18781 atatatcgtg ataatactta tgatatgtag aataacaaaa tataataaat atattactaa
    18841 aataaaatgt aataactttt tatgttaagt ttttaaatta ttaaaagata ttaaaataat
    18901 aaaaagcatt aaaaaagtaa aaatataaaa acaaggtgtc tttatggaaa aatagatttt
    18961 ttctttatta ggcatctttt ttattttttg accaaacttt agatagtcaa aataaataat
    19021 aggtttattt ttttaaaatt aacaaataat actttagaga ggtgtttagt atggataaaa
    19081 attataaaaa atatgtagac caaataagcc caaaacctac atatttaaaa aactatacac
    19141 ttgcatttat tgtaggtgga attatttgta tgatagggca agcaataaat gatttgtata
    19201 tgaaagttgg aggtcttgat aaactaggtg ctagttctgc aacatcaata acattaatat
    19261 ttataggggc atttttaact ggattaggag tttacgacct aataggaaaa agagctggag
    19321 ctggttctat aattccaata acaggttttg ctaactcaat agtatctcca gcaatggagt
    19381 ataaaagaga aggctatgta ttaggtgtag gtgcaaactt atttaaaatt gcaggaccag
    19441 ttttagttta tggtataggt tcttctattt tatgtggaat tatttattat atttttaaga
    19501 tgttttagat gatttttatt taatttaaat tttattaatt atgaagaagg tataaaatct
    19561 gaaaatagct actaaagtaa ctaattgaaa aataattgtg cagatttaat taaaattttt
    19621 aattaatatt aaaaatttga atagtaaaat gcaaaattaa aaaggtgtga aaatatgaaa
    19681 aataaaagaa ttggaaaaag aacagtcaag ttagaaaata aaccaaccat aatatcaact
    19741 ggaactatag taggtcctaa ggaaggtgaa ggaccactaa aggactattt tgatatgatt
    19801 atgactgacg atttatatgg tgaaaagact tgggaattag ctgaaagtaa aatggtagag
    19861 actgcatctc aacaagctat ccaaaaggca ggtaaaaaat tgtcagatgt aaattatatg
    19921 ctaggtggcg atttaataaa tcaaatagtt ccagcatcat ttgcagcaag agaactggct
    19981 attccatttt taggtatata tggagcttgt tctacaatgg cagaaggtct ttgtataggt
    20041 tctatgctta tagatggtgg ttttgctgat ttagtactgt caggtacatc aagtcactat
    20101 tgtacagcag aaagacaatt tagattccca cttgaacttg gaaatcaaaa accaatgaca
    20161 gcccagtgga cagttacagg agcaggaagt gtattattag ctcctaatgg agacggtcca
    20221 aaagtaaagt atgttactgt tggtaaagta atagatgagg gtattgatga tggtaataat
    20281 atgggaccag ctatggctcc agcagcaata gatactatct actcttactt tgaagatact
    20341 aatgatgacc caaatagctt tgatataatt gctactggag atttaggtac tcttggaaaa
    20401 cagatagcag aagactttct aaaagaaaaa ggtgtagata tatcaaaagt ttatactgac
    20461 tgtggtatag agatgtttaa ccttaaagaa caagatgtcc actgtggtgg aagtggatgt
    20521 gggtgttcag ccacagtgtt tgcaggatat atatatgata agttgagaaa aaaagaattt
    20581 aacaaagtaa tgcttgtatc aacaggagca ctactttcac cgacaagtac actacaaaag
    20641 cagacaatac catgtgttgc acatgcagta gtaatagtaa atgagtagga agtgatataa
    20701 tatgttaatg gactatgtaa gagtatttat tgtaggtgga attatatgtt taatagccca
    20761 agtaatgatg gattatttca aaatgcaaac tccatatgtt atggtaacgt atgtaacaac
    20821 tggtgtagtt ttaacttttc taggacttta tgagccatta gttaagtttg cagcagcagg
    20881 tgcaacagtt cctataatag gatttggata ttcacttgct acaggagtaa taaaatcaat
    20941 tcaaagtgat ggttttttag gtattttttt aggaggtaca actgctacag ctggtggaat
    21001 agcagcagct atattctttg gatatattat gtcagtagta tttactccaa aagcaaaacc
    21061 ataaatcttt attaaaagaa taataagttt ttgaaataat aaatttttat aaagcaggtg
    21121 gatatctttt agattccacc tgttttttat ataaagaagc gtttacataa ttgaagttga
    21181 caattattta caacatagtg tagtattata ttatcaaaat aaaatgaagt gaagtagggg
    21241 ataaagatgg taactattaa agatattgca aggaatctag gtatcagtta ttcaactgtt
    21301 tctaggtgct taaacaataa tcctaatgta tctgaaaaaa caaaaaagaa agtggtagaa
    21361 gaggcaaata gactagggtt ccattttaat gtaaatgcaa gaaatttagc aaaaaaagaa
    21421 actaacagga taggggtaat cttttcaaat aattttaatc atcaagatac tagaaagttt
    21481 tttagtgata taatggatag ttctataaat tctattgaga ctaataaata cgattttata
    21541 atacagccta ataataacat tagtggtgat agtaatgtat ataaaatggt aaatggacaa
    21601 atggttgacg gattagtaat tgtgtctcaa tcaataaaaa aagaagagta tgatttttta
    21661 aaagacaata attttccaca tgtatttata tattttaaac catcttttat aggagaagta
    21721 gataatttct tttgggacga taacgtgtat ggaggttata tagctaccaa gcatttaatt
    21781 gaccatggtc ataaagatat aataacagta acttcagatg ataagagttc aaaaatgcat
    21841 gaagatagaa ccaagggata tttgaatgct atggaagaag caaatttaaa gacagaagtc
    21901 attaaatcta aaatggattt tgaatctcaa gttgaatttt tagaaaaata cattgataaa
    21961 ataaaaaaag cttcagctat atttgtacaa caagatgtac cagcgatttc tataatacaa
    22021 gagttaaaaa ctacttatgg tataaatgta ccagaagata tttccataat agggtataat
    22081 aatattgaat taatatcata ttttaggtcg catttatcaa caatagatga cccaagagag
    22141 caagttataa aaaatggagt agatagttta gtaaatataa taaataaaaa gagtacagaa
    22201 cacattccga gaaaattata tccaaggtta ataatacgaa atagcgttaa aagaataaag
    22261 tagtaagctt ttaagtatca aacgtttatt aaaaatatta tagattatgt gaagtttttt
    22321 aacaaataat ataaataaaa attaaaagga gtaggtgtat ataagtacat tgtactcctt
    22381 tatttattga gatagttttt ataatatgaa tgaataattt tattcaatta tttgaaaatc
    22441 cgttatttta acaatataaa ttaataaatt atttgtattt tatatcatga atctataata
    22501 tttttttgat tcataactaa aagtatataa aaatgatgaa taaatatata ttatacatta
    22561 tcaatgatag gttatataat aaaatcacta acaattatat tataagaaaa ttataaaaat
    22621 tacaaggagg tatagaaatg aaagaaaaag cagggattag aaatgccata atagcagcct
    22681 ttataatcac aatattggca gaattaattg gacctatttc atttaaagtt atgggaatta
    22741 atgtaacttt acttagtata ctatgggcta tattcatagg aatggctgtt tctcctcatt
    22801 tattagggag agttatacca gccttaaaaa agtttatagg ggataatgaa ataaatgtat
    22861 ctccatattt attatctttg acactatatc cattagggat aatgtttgga attaatgcag
    22921 ggcctaaagt tggtatatta cttcaagcag gaccagcact tttattacaa gaatttggtc
    22981 atatgggtac aatgttgata gcattacctg ttggagtagc attaggtctt ggaagaagtg
    23041 cattaggtgg tactttttca ttatgtcgtg acacagcact aggaattatt ggagataagt
    23101 atggattaaa ctcaccagaa ggtataggaa cactaggaac ttacataagt ggtagtatat
    23161 ttggaacatt attattttca tttttagcac cagtgggtgt acttttagga tttcatccat
    23221 atgctttagc aatggcatca ggaatgggta gtggttcaat gatgggagct gcaacagcat
    23281 cattaatgaa tacggttcca caaatgtcag agcagatttt agcatattca gctactagtg
    23341 gattgattac agctgttact ggaatatata tagaattatt cttatcttta ccagtagcca
    23401 actactatta tagcaaagta gctccagtta ttgaaagatt tagaggaaga aaaacaagaa
    23461 gaacaagtaa taaattgtaa aggaggatat atatatggaa aaaactttta agactattat
    23521 ggagcagata aaaatagtat tgtttatata tattattatt tgctttggac aaatgatagc
    23581 acttaagact caggctcaag atttgttgat tggaagtgta tctggatttt tgttggtgat
    23641 aattgctatt ataataaaga attttgttaa aaaacctaat ttaccaggtt ttgcatgggc
    23701 tacattagtt gcatttgttt tatcgcttcc aatatctcca gtgggggata tcatagcaac
    23761 aaatgtaggg aaaatcaatt ttatgtctac agtaacacca ttattagctt ttgcaggaat
    23821 ctctgtaggt aaccaattag atatattaaa gactttgagt tggaagttag tagttatatc
    23881 atttatagtt atgacatcta cttactttgg ttctgctttt atatctcaaa cagttttaag
    23941 attaaatgga atgctttaag gaggtagtaa atatgaatga attaaaagca aaaattaaag
    24001 aggaaataaa gttattatct gaagagaaaa agacatcatt tgaaaaagtt tctgactatt
    24061 tattttcaaa tccagaatta gcatttgagg agtataagtc acaaaaagca ttatgtgatt
    24121 tgttagaaga aaatgaattt aatgtaacta aaggtgtagg aggattagaa acatcttttg
    24181 aagctgtgta ttcaaatgga actaatggga aaacagttgc ttttttagct gaatatgatg
    24241 cacttccagg aatgggacat gcatgtgggc acaatatcat agggacaagt tctgttggtg
    24301 caggtatcat attaaaagaa atcatgaaaa aacataatat agaagggact gtaaaggttt
    24361 ttggaacacc tgcagaagaa agagtaggtg gaaaaataac tatgattaaa gaaggtgtat
    24421 ttaataatgt agatgctgca ttaattttac atccaagtga tgcttcaatg cctgatgata
    24481 tatcatttgc tcaagttaat ttaaaatttg attttactgg taaggcatca catgctgctg
    24541 cttttccttg ggaagggaaa agtgccttaa gtggagtaat agcactattt aacagtgtaa
    24601 atagcatgag attacatctt aaagattatg caagagtaca tggaattata actgatggag
    24661 gtagcataca taatataatt cctgaaaaat ctacagctat atttaatgta agagctttaa
    24721 gcatagaata tttaaatgag atttgtgaaa tgcttaaaaa ttgtgctaaa ggagctgcaa
    24781 tttctactgg aactaatgta gaaatagttc aattagatga aatatacaaa gagattaaga
    24841 atgattctga attagtgaat atagttagac aaaattttga agttttgggt gaagactatg
    24901 ttgaaagaga tttaagtcaa ggtataggtt caactgatac aggaaattta actcatgaga
    24961 tacctgcaat acaagcatat ataaaattaa aagaaaatac tgcaactcat acagatgaat
    25021 ttgctgttgc agctggtggt gaagaaggca gagtagcact tataaaagca attaaggtgt
    25081 tagcaatgtg tggagtagat attttgtata gtaaataata tataatttta aaatatatta
    25141 agaaaggaaa tcggattaga catgatatta aaacaagtaa tagaggttta tgacatttta
    25201 gataaagcaa atgctaatgg ggaagaagta aaaacttact tacaaggtta tggtgaagta
    25261 gatgtaactg taaaagaatt gtcttcaagt aaaggctcaa cagatttagt aaagcttaca
    25321 attcctggga aaaatggaaa attaaaaggt ggagatgctc ctactcttgg cattttaggt
    25381 agactaggag ggattggagc aagaccagaa gttataggtt ttgtttcaga tggtgatgga
    25441 gcattggtag caattgcagt ggctgctaaa cttttggata tgcaacgaaa aggggatata
    25501 ttagatggtg atgttgtaat ttcaacccat atttgcccag atgctccaac taaagaacac
    25561 tatcctactc cttttatgga ttctccaatt gatatgatga ctatgaatga aaatgaagtt
    25621 gatagtagtt gtgatgcaat actttctata gatactacta aaggaaatag agtaatcaat
    25681 actagaggat ttgcaatatc gccaactgtt aaagaaggct acatattaaa aactagtgat
    25741 aaccttttag atattatgca gactgtaaca gggaaatctc catttgtatt ccctttgtct
    25801 attcaagata taacaccata tggaaataat ctgtatcact taaatagtat tttacaacca
    25861 gcagtagcta cagatgcacc aatagtagga gtagcaatta caacagagat gcctgttgct
    25921 ggatgtgcta caggtgcaac taattttagt gatttagatt cagctgggag atttgcaatt
    25981 gaagttgcca agctatttgg tagaaataag tgtgatttct atgataaaga agagtgggaa
    26041 atgcttatta agagatatgg caaattaaat agatttcaaa catttggtat acagtaatta
    26101 gaaaaatatt aagtttatat aatttgtgat ataactattt aagaatatat aaacaattag
    26161 gaataaaagt aagaataaag cacttagtta aaaactttaa aaataaaata tttatttgtt
    26221 tatataaaaa ggaggattct ggttattggg attctctttt ttatgaatac aaataatata
    26281 ttgtaattat aaaaaaagga gcgtttcaaa gtgatttttt taatcacctt gagacaactc
    26341 cttatatttt tatttaaatt ctatttttta ttaagttgct ggagttccac caccatcagg
    26401 aggagtagta gagccaccac cattatttcc accattatca ggaggagtag tagagccacc
    26461 accattgttt ccgccattat caggaggagt agtagagcca ccaccattat ttccgccatt
    26521 atcaggagga gtagtagagc caccaccatt gtttccgcca ttatcaggag gtgtagaacc
    26581 gccaccatta tcacctgtgt tattattgtt attattattt tcttctggtt ggttattgtc
    26641 tggttttttt gtatcttcag atgatggttg agaacttact ttagtaggag cagtaccttc
    26701 aataaatgct gctttagagc cagaagattg ctttcctcca tcctctaaat taatttttgt
    26761 aaaatataca tttttaggaa cttcaaattc agtaaccgtt aaattagcat gtattttttc
    26821 cataattttt tcccatagtt ttgcagtact agtacttcca tgtgggactt ctctacgttt
    26881 tatagtgtta ccagaatcat cttttctacc agcatcatct ccaatataag ttgcaccaac
    26941 ataataagga gtgtaaccga caaaccaagc atcatatgca ctatttgtag tacctgtttt
    27001 acctgctaca ggcattccct ttggaagtgt agcaacacca ccagtacctt cagtaattac
    27061 gctttctaac atatctgtaa caacataagc tacttcaggg tctacaactt tatgttcttc
    27121 aggagcattt ttaactaata attgaccatc aaaggtagtt atagtagtaa aaatagaagg
    27181 ttctacataa ataccgtgat ttgccaatgt accataagca gcagccattt gaagtggagt
    27241 aataccattc gccataccac ctagtgtcaa tgatgggaat tttctatcac ttgcttcaga
    27301 tgaacctgag tgattattct ttaaagttgt tataccaaag ttctttaagt aatccatcat
    27361 tatatctaca cattcatcat aagagtctcc aagcatttca gcagttttga cagctatcgt
    27421 gtttgaagat ttagcaagtg ctttacgtaa actcatagaa ccatgaccag cagtagtagt
    27481 tcttggattc cattcattat tttctttaaa cttatatcct cctcgagaat cacttagagc
    27541 agttgcttgt gttattttta gagtatcaat agctggcgta tatattgcta aaggttttat
    27601 agaagaacct ggctgatgag ggttagtagc acgatttaaa gtttttctac cacttatatt
    27661 tcttcctcca gctagtgctc ttatttcacc atttttataa tctaagatta ccattgcagc
    27721 ttgcggttgg ctaactccat caggaccgac catatgtcct gggaaattgc tatttctatc
    27781 aaattcttct tctaaagcat cttgcatttt agggtctata gttgtgttta caattagacc
    27841 accattgtag aataagtttt gagcttcatc atttgtatgt ccttgttcca ttaaagcatt
    27901 tataacttca ctttcgataa ggtcttctac agatgaagaa actttatctg atgattgagg
    27961 caattttatt tctattttag ctttgattgc ttcatcatat tcactttgtt ttatatattt
    28021 caattctaac attttcttta aaacaatttc ttgtcttttt ttagcttcag gattacttac
    28081 agcctttcta acaactaatg tacctgcttt taattgtcta taagtatcat tagatataag
    28141 ctcccaagat tttatttttt caatcatatc aaagtccact tgagtagggt catctaaatc
    28201 atcatcagtt gtgttaacaa aaaataataa tttattctct aaatcctcct tagtttcatt
    28261 tccctctaac ttagaagttt tataggctga aaatcttgat ggatttttag ttgaaccagc
    28321 aagaagtgct gactctgcta gagtaaggtc agctgcagac ttatcaaaat aaccacgtgc
    28381 accagcctca gcacctgcta gacctctacc aacgaagaag ttatttaaat aagtttctag
    28441 tattttatct ttacttactg ttttactcat ctcatgtgca tagtaaatat cctttatttt
    28501 acgaggtata gtttgctgtt cagttgttaa cagcattttg gatacctgca taggaatagt
    28561 actaccacct tgcttagtac ctgtaagggt ctttaatact gacctaaata aacctttaat
    28621 atcgacaccc ttatgctcat aaaaacgctc atcttctatt gcaattacag catgttgaag
    28681 ataaggggaa atcttatcta atggaacggg tgtcttttta tttacacttg gagctgtaga
    28741 taatgttttt ccattagcgt atttaatagt agttgtttgg ttcgtctgtt tatctaaaac
    28801 agcttctgta actggagtta catctcttag tgacgcaaat actagaccag cagtacctgc
    28861 tgtaccaaca actagtaaaa ctaaaaatac tatcccaaat actcttagtt ttttaaattt
    28921 atcgcttttt ttagattttt tcttgttttt tgttgaacga gtcttgttag ctgaagttct
    28981 attaattggt ttatttgtat taccagatga gctaactttt tttctcctga ttttatttcc
    29041 atttttatca ttatcgttat tcataagatt ttaacctcct tacttaatgc aatattataa
    29101 cacaaatagg agtagttttg taattaatag aaaaaatgaa tttgctataa tattctgtac
    29161 attgtatatg tataaacgta atatattaaa aagtctatat ttttatttta tttatttttg
    29221 acaaatatta taaaaattat gccaaagcta catataaata aataggaggg gataattttg
    29281 aatagaatag tagatagaaa aacaaaaaat gaatttagaa aaatcatagc tattttttta
    29341 gtaattcttt tcttgtctgt atttataggc agttttatat atatagataa aactttaaga
    29401 ccgacaataa cagttttagc agagactaaa gctcttgaac tagcaaatag gtcgataaat
    29461 aaagctgttg ctgagatggt agaaggaaaa ataaattatg aagatttaat ggatatacaa
    29521 cttgataata atggtaaaat aactatgata caagcaaaca ctataatgat gaatgaaatt
    29581 gcatctgcaa tagctttaga aatacaagat gaattaaaaa aggataagac agcaagttct
    29641 tacataccta taggaacagc attaggaagt cctatattag ctaaatacgg tcctaaactt
    29701 gaagtatcta ttgaacctat aggaacagta tcagtaaact ttaaaacgga atttgagtct
    29761 tcaggtataa atcaaactag acatagaata tatttagaag ctcaaacaca agttaaagta
    29821 gtaataccac ttataacttc aacaaaacaa attaaagctc aaatacctat ttgtgaaact
    29881 ataatagtag gtgatgttcc agaaagttat gtaaatattc cagaaaaaaa tctaggaaat
    29941 gttttaccta acactggaaa gaataccaac aagtaatata aagttgtata tttttaaata
    30001 aattcaaaat aatagtttat aaataaaatt tttggaaata atattaatat aattttaata
    30061 aaaatttata ttttatacta tgtaaaatat ctaatatatt tggtctgtag gttaaataaa
    30121 agtaccttta gaccaaatat attattaata acttaataac atcttaaaac ttatttattt
    30181 atttatatta tttacaacat ccatttaata aatacaccat aacctacagc tgggtcgttt
    30241 tcaattgcat gtgacactgc tccgattatt ttattatctt gaactattgg agtaccactc
    30301 ataccttgta caataccacc agtttgagct aaaagctttt tatctgtaat tttaatttta
    30361 aaacttttac tttctggatg tttttggttt tctatatcta taatttcaat attatatttt
    30421 ttacacttat taaagttatc ttgtaaaatt atttgtgctt ttcctaattt aacttcatct
    30481 aaagatgcta ctttatattt ttttaacttg gaaatatcaa agttattaat ttgacctctt
    30541 attccaaaat cagtattttc tgtaaagcta ccaataatat tttctcgttt tgcatttata
    30601 catccaacac tacctttata agatttttct atattaaggt gcttagttgt agaaattgaa
    30661 cctgttttaa taggtatttt tcttgcatta ccaacactta ttggatgacc tacagctcca
    30721 aactctgatg tatctggatt gatatacgtt aaagtagcaa atccagaaag taaattgtta
    30781 aaactaattt tttctaatat gtgtttggta gttttcattg ttataagttg tccacctcta
    30841 tttaataaaa tagatacttg tttttcttct ggtaaagcat ttaaggtatt ggcaaagtca
    30901 ctatatccat caacttcagc attatttacc tttactatag catcacccaa tctaaatgga
    30961 gatgcttctc caggatttct aactatgata ttttttaatt ctgcgtcaat ttgaagtacg
    31021 tttccaattg gtattaaata ttcaggttca tttttttgta aattttgtgc ataaattaaa
    31081 ttatttgaga aaaaatataa taaaaataaa aataaaaatg ttaaaacaat tgtaaatttt
    31141 gacttagcta agttggtttt tttacttaaa gtattatttt taaaatgaaa atttttaagt
    31201 tgcataaaac acctctttct tattaaatta ttttaataat agaattgaag ttttcttgct
    31261 gcttctatat tatgttgtgc aagaatcatg ttttgatgct tggaaaacta gctcaataac
    31321 accttagttt tcataaaaat aaataaaata aatagtgtat atgataaaat aaatacatat
    31381 tcatataaat aaaaataaac aataactgtc tagcataaga aaggagcaaa aaatgaaaaa
    31441 atatagattg ttagttactt gtataattgc catgggaatc ataattatag gaacatcaaa
    31501 tccagttagc aatttttaca agactacaaa tttgattagt tcaggaaata tcacaaatga
    31561 aaaagcaaat aaagatgaaa attcaaacaa aaataataaa gataaaaatg aagacaaatc
    31621 taattctaaa agtaataaag ataagtcatc agaggacaaa tcgtcagata ataaaaatga
    31681 aattcaaaaa aataaaaaac ttttaatttg tatagaccca gggcatcaag gaaaaggaga
    31741 tagcaattta gaaccagtag ctccaggttc ttcctctaaa aaagcaagag tatcttcagg
    31801 aacagagggt attgctacaa aaaagccaga atatgtttta aacttagaag catctcttgt
    31861 tttaaagagt atattagaat ctaaaggtta taatgtaata atgactagag agacacatga
    31921 tgtaaatata agtaattcag aaagagcaat acttgctaat gacaaaaaag cagatatggt
    31981 tgtaagaata catgcagata gtttaaataa ttcttcaaaa actggagcat ctatattgat
    32041 tcctgaaaaa gatggaaaat atacagctcc tatatatgaa gaaagtaata aatgtgctga
    32101 atttatcaaa cagaatatgg aacaatcagg tatacaaatc aatggaatcg ttcaaagagg
    32161 tgatttgact ggattcaact ggtcaaaagt accagctgta ttagtagaaa tgggatttat
    32221 gagtaactat aatgaagacc aaatgatgtc aaatccagac taccaaagaa aaatgatgca
    32281 gtgtatagct gatggattgg atgcgtattt taaataagat atgaatagag aaaaagttag
    32341 gttggtatta ttttcctaat ttttatctct attttttatt gtacataaca caaagaagaa
    32401 gtttatttta ggttaaattg tcgtaaatat aactaaaaat attgggaata cttgatttaa
    32461 gtttaaaaag aatatattat agtatagaat gtgtaaaatt tttttgagag gtgttgaaat
    32521 gctagtagta gaaaatgtga gtcatggatt tggtgcgaga acaatattag aaaatgtatc
    32581 ctttagactt agaaaaggtg aacatattgc actagttggt gctaatggag aaggaaaatc
    32641 gagtttttta aatataataa caaagaagct tatgccagat gctggaaata taaaatggtc
    32701 ttcaagagct acagtaggtt acttagacca acatacggta ttaagcaagg gaaaaactat
    32761 aagagaagtg cttagagagg cttttaagca tatgtttgac ttagagcaag aaatgattgc
    32821 tatgtatgac aaaatgggag aagctagtga tgatgaaatg agtaagcttc ttgaagaaac
    32881 agcagagata caaactatac ttgaaaatag tggtttttat atgatagatg caaagataca
    32941 agaagttgca aatggtcttg gtcttggaga aattggtctt gataaagatg taactgactt
    33001 aagtggaggg caaagaacaa aagtacttct tactaaactt ctacttgaaa atccaactat
    33061 tcttatattg gatgagccta caaactattt agacgaagag catataacat ggcttactaa
    33121 gtaccttcaa gagtatgaga atagttttgt cttagtttct catgatattg aatttataaa
    33181 taatacatgt aatgtaatat atcatatgga aaatggagag ttaaatagat ataaaggaaa
    33241 ttatgatgaa tttgtaagac ttaatgatat aaagaaacgt caagaagaac aagcttatga
    33301 taaacaagtt gaagaaagaa aaagactaga ggattttgta gctagaaata aagctagagt
    33361 agcaactaga ggaatggcta acagtagaca aaagcaactt gataagatgg aaatattaga
    33421 aagaccaaaa gaaaaaataa aacctacttt tgcttttaaa gatgctagag cagctagtaa
    33481 aataattttt gaaacagaaa atttagtttt agggtatgat gaagcattga caaaaccact
    33541 taatttccat ttagaaagag gaaaaaagat tgccttaaaa ggaatgaatg gtattggaaa
    33601 atctactcta ttaaaaactt tacttggaat aataaaacca tttgaaggaa atgttaaatt
    33661 aggtgactat ttggaagttg gatattttga acaagagagt tcaagagaaa atagtaatac
    33721 acctatggat gaagtttgga gtgaatttcc agggcttaca aactttgaag ttagacaggc
    33781 tcttgcaaaa tgtggactta caaatgaaca tataacgagt caaatgagag tattaagtgg
    33841 tggagaagct gctaaggtta gactttgcaa agtaatgtta aaaaatataa atttcttagt
    33901 attagatgag cctacaaatc atttagatgt tgaggcaaaa gatgaattga agaaggctat
    33961 caaagagttt aagggaacag ttcttttagt atgtcatgag ccagaatttt attcagaaat
    34021 tgttgatgat gtatggaata tagaagattt tacaactaaa atcgtgtagt gatttaactt
    34081 attgctgggg ggatttcatg aaaaagtttc taaatgtact tttttcaatt tgtattagta
    34141 ttgttataat agtaggtgtt attaatttta ctgttggatt taaacaactt tattattttg
    34201 acattgatta cttaaatata tcagagttat ctggtttatc taaagatgat ataaaattga
    34261 actacgatta tctaattgat tataacttaa ataagaatgt gtctgagttc aaattaccaa
    34321 cattaaaatc ttctccacaa gggaagatac attttgaaga agtcaggaat atatttcaaa
    34381 atataaataa attagctaaa ttattattgg tagtttcttt agtaggaatt atattgagtg
    34441 taaaaaataa aaatataaaa atcttaaaaa ctacatcaat aacacttata attatgccat
    34501 tattattaac agttccaatt ttattaaatt ttgaaaagtc atttattatt tttcataaat
    34561 tattatttag aaatgattat tggatattta atcccgattt agacccagtt ataaatatat
    34621 tgccagagga attttttttt cactctggaa tgatgatttt aatattaatt ttgttagtaa
    34681 gtatagtact gtttgtaatg tataaattat gtaaatcttt atcaataaaa atatttcaat
    34741 gttaaataga gggatatttt tatttccaaa ataagataat aaaaaaggat tagattaaaa
    34801 gttatacaat aaaaatagct gtgcaataat atttagacta tgaaagtagt taaaaaatat
    34861 ttatgcacag ctatttataa tagaatttac tttttactag tgattttaac taaatcttga
    34921 aatttactca taatgtaatt gtaattatct tttttatgag gtaatataca actactgcaa
    34981 tctttgatac ctttatctgt atacttaaag tttccaccac agttttctcc taaagcatac
    35041 aaaggacaat agcaaaatag acagttaaac tcttctggtt tattagtttt atgacaaggg
    35101 aaaaattcgc aatctttgtg attaaaaaac ttataatttt cgcccatatt ttcctcctaa
    35161 ttaaataaaa tttaaatttt ttatactata taagattttg gtgataatat aattatacta
    35221 aataatttta tgaatagtcg ataatatagt attattaatc atagtattaa tggtataatt
    35281 agtcaacaga aaaataatgt aaaaataatg taagtgtatt ttgtaattag aatatgtttt
    35341 ataacaaaaa atgaggtgat taagtgaaag aaattcaaga aaaagcactt cttgtaggtc
    35401 tgaatttgac tacaatagtg aaaaaaaatg atgatataga cactaatgaa tctatggaag
    35461 aattaaaaga actaacaaaa gctgctgggg cagaagttgt aggtagctta attcaaaata
    35521 aacactctgt agatgcagct tattatatag gaaaaggtaa agtagaagaa ataagagcct
    35581 atagtgactc tttagatgct actttagtaa tttttaatga tgaattatct ggtgctcaaa
    35641 tcagaaatat agagaatgtt gttggaagaa aagtaataga tagaactact ttaattttag
    35701 atatatttgc tcaaagggca cttagcaaag aaggtaaatt acaagttgaa ttagcacaat
    35761 taaagtatag attgccacga ctttatggaa tgggtggtga gatgagtaga acaggtgcag
    35821 ggattggtac tagaggtcct ggagaacaaa aactagaaat agataagaga catatactta
    35881 ataaagcagc agatataaga cgtgaactta aagaagtaaa aaagaataga gagacacaga
    35941 gagttaagcg tttaaagtca aatataccga ttgtagcact tgttgggtat acaaatgcag
    36001 gaaaatctac cctgttgaac gaattaataa agacacacaa ggattatgaa caagaaaaag
    36061 aagtttttgt aaaagatatg ctttttgcaa ctttagatgt aaccttgaga aaggctcttt
    36121 tgccgaataa aaaagaattt ttagtagtag atactgttgg atttgtaagt aaacttcccc
    36181 atgatttagt agaagcgttt aaggcaacat tggaagaagt acagtatgca gatttaatct
    36241 tacatgtaat tgatgcaaca aatactagtt atgaattgca aaaaagtacg actgaaggtg
    36301 tattaaaaga acttggtgta aatgataaaa aacatatact tgtatataat aaagtggaca
    36361 agctagaatt ggatatatat cctaaaagtc aagaagatat tgtgtatatt tctgcaaaac
    36421 aaggcataaa tatggataag ttattaaata tgatagaaat tgctttaatg gaaaatactt
    36481 attcagtaag tttgatgtta ccttatgaga gaggtgatat atttagtaga ataaaagata
    36541 aatataatgt ggagaatttt gagtatgggg aaagtggtat aacgctagat gtagatttag
    36601 atgaagaaga ttttaatatc tatagagagt acatactaga aaaataggtt gaatatggat
    36661 ataaactggg aaaatataga taatcttgaa gattatttta taacctatct tctttataaa
    36721 gaatctaaaa cagtatctca aattagtaaa attagaaata tttcaagtac tgaagcaagt
    36781 gagcaactta tacaagcaaa gttaaaaata aaggaaatgc aaaaagatga ttttgaggca
    36841 tctaaggata ttttggataa atttctagaa ctagataaaa ttaagagact tgattttatg
    36901 gatagcttag atgacgaaaa aatggtatac tttaagagaa aggttttcaa aagaatcctt
    36961 gtagaaaaaa atgctgaaga tttaattgtt ttaatttggg cgacaggtga gctaaaagat
    37021 gataggtttt tgaaattgct tcatcagctc acaaaccaca gacactcaga tattagaaga
    37081 ataacttatt cagcaatcag aaagattgaa tcaccaagta gtagagaagt actgcaaaaa
    37141 ggtctctacg acaaaaatgc acagactagg cagtactgtg caaaagctct ttcaaaattg
    37201 ggagatgaaa acagtttaaa gattttacag cagttgaaag acaagaataa gaattttgaa
    37261 aaagaatatg tgcttagagc ttatgacaaa gccattaagt cattggaaaa tgcaaaaaat
    37321 ttgaaaaagt aattttttat taaagcaatt tgtttactta atgatgtatt tctaaagttt
    37381 aacaaggtaa taaataaatt aatgggaggg gtttcaaatg atagtaagac gttgtgcagg
    37441 tggagtagtg ttttatgcta ataaagtact tattgtaaaa aatgataggg gtgaatggac
    37501 acttccaaaa ggaaagatac taggaggggg acttccatat gagagtgctg ttcaaagagt
    37561 taaagtagaa actggcatag atgctaaaat gatagatgtg gctggcgata ctatgtatga
    37621 atttttctca agaagtagac aacaagaagt ttgtaatgca ataatgtggt atgttatgga
    37681 agcttgtaac actgattgtg tacttgctcc tgaatttcaa gaaggtggat tttataaagt
    37741 aaaggatgct ttagaaatgt tatcacatca taaagagcaa gctttagtag aagtatctta
    37801 taaaaagttt aaggaattaa agaaattagt ttcagagggc gatgatgttc cagcaaatta
    37861 attgtgaatt tagaggattc tgaggaaggg atagcccctt ccttttttaa ttgaagcagt
    37921 tttaagcgta aattatatag tctctttaaa ctatgattta tcaatttaga gatttagtag
    37981 tttatattta aaatcagtaa gatatattta aaataaaaat taaaaagtat acaattttat
    38041 tatataattg tcttatgatg ttgattaaag aattattaaa agtccattta tttttaaata
    38101 gaataatttt ataaatatat atttgatgtg tatattagaa aatgattaaa ataggaggaa
    38161 atacaatgag caattacagg acattacatg aatttggaat ggatgaaata acgattgaaa
    38221 agtctgtttt tattggatat gctaagccta taaagagtga agaagaagca ttagagttta
    38281 taaatgaaat aaagaaaaag cataaagatg caactcacaa tgtgtgggct tatactgtag
    38341 gtaaaaatat gaatatacaa agatatagtg atgatggaga accacaagga acagctggga
    38401 tacctacatt agaggttata aaaaaagaag atttgagaga tgtagcggtt gttgttacta
    38461 ggtattttgg aggaacaaaa ttaggtgcag gtggtctagt tagagcttat acaaaaggtg
    38521 ctaaactggg acttgaagca ggtaagataa tttataaggt aatgtatcaa gaagttaagg
    38581 ttaagataga ttatactcaa cttggaaaag tgcaaaatga gttaatgaat ttggggtatt
    38641 ttataaaaga tactgtatat gaggataatg ttgaaatagt agtatattca agattagaag
    38701 atgtagagaa attatcagaa aaaatgattg atataacaag tggaacagga aaaatagttt
    38761 taggagagga attttatttg tctgaacaaa atggagaaat tttaatataa tctaaaaggt
    38821 tattagaata gttaatacct caaatagcca attagtattt ttaagtgaaa agccattaaa
    38881 ttgatttaat ctaaatcaat ttaatggctt tttatcggat tttgcacaga atcctttttt
    38941 tacttcaaat aaaccgacta aaagtaaaaa tatcccaaat atttttttta atatatctga
    39001 agacagataa ttagctaata gtgaaccaaa tacagctcct aaaaccccaa acacagctat
    39061 aggtataacc aatttaaaaa ttacattttt attttttata tgtatagcaa gtgctataag
    39121 tgtcataggg atagatgaaa gtaaatttac gctttgtgct attttagtgt ctatgccagc
    39181 aagtaaaacg agtgcaggta taaggattgt tcctccaccc attcccattc ctccaataat
    39241 tcctgcaaaa aatccaatta gagcaaataa cattaaaaca ccatccttaa tgctgcaatt
    39301 atcataatta ttccaaaaga aattctaaga aactttccag taaccttatt tagtaattta
    39361 gctcctataa taccaccaag aatacttcca actgcaactt taattgttaa gttaacatca
    39421 taagtacctt tagatacata taaaacagaa cttgctgtcg ttaagaatat tattatagaa
    39481 agagcagttg catgagattt atgttcttct accttaacga tgtcatttaa tattggaact
    39541 aaaagagtac ctcctccaga accaaaaact ccatttataa atcctgtaaa aactccaatt
    39601 atcgtatttt ttaagttaaa atcaaagtat tttttcttta aatcatcagt ttttttcata
    39661 aaaatcacct tctgaaatag ttttaccaaa ataggcaaat tatatttata taaaataaga
    39721 ttaaatataa tctttcatgt ttgtttaatt ttgcataaaa aaaaacatat taaaacaaca
    39781 tattaatata tggtataata tattaaaaca aagtagcaaa tttgagagga gataacaatg
    39841 tcaaatataa aaatacaaat agacaaaact gtagaatggc ttataaataa ggttaatgag
    39901 gcaaatgcaa aaggattaat tgttggtgta tctggaggaa ttgattcggc agtagttgct
    39961 aatttaatta aaaaggcatt tccagaaaac tctatgggag ttataatgag cataaaaagt
    40021 aatcctcaag atagagaaga tgcacttaag gttatagagg gatgtgatat agaatacctt
    40081 gatttagacc ttatagaacc acaaagtgct atattagaca tggtagtagg aaatttaaaa
    40141 gataaacatt tatatagaga agaatattta aagatgacag atgcaaactt aagagcaaga
    40201 gtaagaatga gtacaattta tacaattgct aacaatctag gatatctggt tgttggtaca
    40261 gacaatgctg cagaaataca cacaggatat tttactaaat ttggtgatgg tggagttgat
    40321 attttaccta ttgcaaattt aactaaagga gaggtgtatg aatgggcaaa agagcttggt
    40381 gttcatgaag atttaataaa caaagctcct tcagcaggtc tttgggaagg tcaaacagat
    40441 gaagatgaaa tgggaactac ttacaatatg atagatgctg tgttagaagg tagattggat
    40501 gaagttccta aaagagacca agagataatt gaaagacttc atagattaag tgaacacaag
    40561 agaaaaacgc ctgcacaacc tcctaagttc taatttacta tttataagat ttgtgataaa
    40621 atttacaagt gatgaaaatt agaataatta attgtacgta ttaaggagtg gaaatatggg
    40681 acgtataggt aatataatta atagaaaagg taaacaagat gctcaaagag caaagatatt
    40741 tactaaacat gctagagcaa tagcagttgc agctaaggaa ggtggagcag acccagagta
    40801 caatgcagcg ttaaaaacag ctatagaaaa agctaaggca gataatatgc caaatgataa
    40861 tatagataga gctatcgcta aaggtgctgg agcaggtgct ggagaagact atgaaactat
    40921 agtttatgaa ggatatggac ctggtggagt tgctgttata gtagaaactt taactgacaa
    40981 caaaaacaga actgctggta acgtaagata ctattttgac aaaaacggag gaaacttagg
    41041 aactagtgga tgtgtgtctt ttatgtttga taaaaaagga caaatattag ttggtttagg
    41101 agatggagtt tcagaagaag aattgatgga tgttgcatta gaagcaggag ctgaagattt
    41161 cataacagaa gaagatggtt atgaaataat aactacacca gaagattttt ctagtgttcg
    41221 tgatgagtta aaagctaaag gatatgagtt tatatctgct gatgtgaaga tgatacctca
    41281 aactacaact gtattgactg aagaatctca tttaaaaatg atgaataaat tagttgatat
    41341 gcttgaagaa gatgatgatg ttcaagatat atatcataac tgggaagtag aataaatagt
    41401 ataagcatat tgaaatttat aagtattgaa tcaattttaa catgtgataa attttataga
    41461 ataagaaaca ctaaaataga catacgcacc tctaacctat atttgcataa taatatgtaa
    41521 gcataggtaa ggggtgtttt tatatttata ggttaagaaa tttaaagtaa attttgagct
    41581 ggactcgatt gtctataaat aattgatggg tatataactt gttgctgaat accatttata
    41641 cgcccagtta ctgtatcaat aatcatccta agactacgtt ctgctgtctc ttccattttt
    41701 aaatctataa ctgtcaaagg aggaatactt cttgccatta gtcgtgaagg tccattactt
    41761 gctgcaaata tttgaatatc ctctccaatt acaattcccg attcatgaaa tgcattcatc
    41821 ataccaagag ctaccacatc atgattacaa aaaattactt tttttagtga attttttgca
    41881 agcatttttt gagcaatatc atatccacta tctattttat tagaacaata atatatagaa
    41941 tctgatagat gtattccatg ttctttacat gtttttaaaa aagatttacc ccttaaagtc
    42001 atacatgtaa aggaagttgg gttgaataca acagcaatat catttttacc attttgaata
    42061 gcatgtaaag ctgctatacg accagtttcc tcattatcaa tagatacact tgaaaaacca
    42121 ggtatttcac gatttacaac aactacagga attttaggtt tattttttac tagatattct
    42181 atatcatcag cattgatacc tgttaaaaca attccatcat aataattatt tgcaaaaaag
    42241 tattcatcat cacatagatg accaactttg taaggtcgta tgatgatatt tatgtttaaa
    42301 tgttctaaag aaattatgtg gtttattgct tgaagtatat tggttgatgc caactcaaat
    42361 ccctcatcct gccaataaaa agctatttta atattattat gtttaatagg agtagagcgt
    42421 ttatatccaa gcttatcagc tgaatttaat ataagctctt gtgtatgtag cggaatcctg
    42481 cgttcatttc ctttaccact taagacgtac gagacagttg ctgaagaaag accacagtct
    42541 tttgcaatat ctttgattgt tgccatgata aaatcctcct taaatagttg cttaaatttg
    42601 cttataccaa taatcttaac atatattcaa ctaaagaaca atattctaca aggtgcatat
    42661 tttacagaat tagaataaat aaatttaaaa aaacttctta cttatgttga cataatttag
    42721 tttataggat tataatatgc ttaaataagc ttattattaa cttaaattaa gcaaagttaa
    42781 gcaggaacat gcaatgctag cttgcaatgt gactgtaaag ggggaaaagg tatgagtaag
    42841 gtaaatatat ttgaagttgg tcctagagat ggatttcaaa acctgaaaga gtttttagaa
    42901 actgataaaa agcttaagat tattgatggt cttattgctt cagggattaa acaacttgaa
    42961 attagttcat ttgtaagccc aaaagcaata cctcagatga aagatgcaaa agaagtagca
    43021 acttattgtg tagaaaaata tcctgatgtg aaactttatg cattagttcc aaatttatac
    43081 ggtgctaaag ttgcatggga gtgtggtata agagatatat cctatgttat atctttgagt
    43141 gaaactcata ataaaaaaaa tataaatcgt acccatgaag agtctattga tgagcttaaa
    43201 aaaataatga atacttatcc agacatgaat atatgtattg gaatggctac tgtatttgga
    43261 tgtccttttg aaggtttacc aaaaattgaa gatgccataa gatttgctaa acgcctttgg
    43321 gaaaacggta tcagggagat gaatctagca gatacaatag ggattgctga ccctaagcaa
    43381 gtaagagaaa ctattagtgc attagttgaa gctttaccag agtgcagatg gcaggtacat
    43441 attcatgata ctagaaatat gggaatggtt aatactcttg tggctattga atctggaatt
    43501 actactgttc agtctacact tggaggatta ggaggatgcc catttgctcc tggagcatct
    43561 ggcaatactg caactgaaga tttagtatat atgcttgaac gtatggggta tgatacagga
    43621 gttgattttg ttaaacttct tgaattatca aagtatcaga agagttttgt aaatggagta
    43681 tatagtggtc atcatgtaaa tataaagtct gatagttgta attgttagtt ctattgatta
    43741 atcgattaaa aaaatatgtt gattaaaaaa atatgctgat tggtaaaata gatttattga
    43801 taaaaaatat aaattataaa atacattatc taataaaaca aataaaaaaa ttgaggggga
    43861 ttagtatgga tattatagct ttacttttat ttttaggagt tattattatt gcatttgtac
    43921 gtaagaataa tgcaggtatt ttggctctag ctattggtgt catagctgtt agaatttttg
    43981 gaatggatga taaagaactt tatggagcta taagcaactc aatgtttact acacttgttg
    44041 gtataacact actctttgca atagtgaact caacaggagc attaaagctt gttgcagaaa
    44101 aaattgtagc tgcttctggt aaacgtgttt ggcttatacc tatagcagtt tttatagcag
    44161 gatttgttgt tgctggtgtt ggacctgggg caattccagc acttgcaatt atcccagcaa
    44221 tggctgttcc tgtagccata acggttggtt ataatcctgt aatgcttgca cttataggtg
    44281 aatgtggatt aatggcaggt cgtatgactc ctattactcc agaaggtcaa attataacaa
    44341 ccgttgcaga aggggttgga attgaaaatg ttatgcctac tatcttagcc tgtcaaactc
    44401 tttctacaat tgtattttca atagtattgt ttataatttt caaaggatat aaacttaaaa
    44461 aacctataaa tgttatagat agtaagcaaa tagaaaaatt caatataaag cagataattt
    44521 ctctaataag catagtagtt atgattgctt ttatcataat ttttgatatg aatgttgggc
    44581 ttgcagcttt tgcagtttca gctgtactta tttttttcaa tattgctgat gaaggagaat
    44641 gtatcaaatc aattccatgg agcacgatag taatggttct tggagtaggt gcaatgatga
    44701 caatcgtaga tgcagcagga ggtattgact tgatgagtaa tgcattatca tcactgatga
    44761 atagtaaaac agctactcca attatgagta tttcagcagg acttatgtct atggttagtt
    44821 ctgctttagc agtagtttat ccaactatga tgcctatgtg tgttgatata gctaaggcag
    44881 ttggaggagt agacccacta gcacttattg ctgcagttgg tgttggaggt tctcttgctg
    44941 gtgtaagccc actttctact ggtggggcat tgattttagc agctatgggt tcaagtaaga
    45001 aagactttaa taaggaagaa caaaataagg tttttgtaca gcttttcatt atgagtgcag
    45061 ttggcttatt ggttattgca gtagtatcaa tattatcatt taatgcaata acacatttaa
    45121 tgaactaatt agaataactg aaaataaatc attaaattta acttttaata ttaatcaata
    45181 taatataatt tggaggggaa gttatgaaaa aaggagcatt aagcaatata aaggtacttg
    45241 accttacaag agttcttgca ggtccatatt gtacaatgat gttggcggat tttggagctg
    45301 atgttataaa aatagagatg ccaagaaaag gtgatgatac aagaggtttt ggaccttttg
    45361 taaatggaga gagtttatac tatgcaaata taaatagaaa taaaaaaggt atcactctaa
    45421 accttaaatc agaagaagga aaaaatatat ttttagaaat ggtaaaacat gctgatgttg
    45481 tagtagaaaa ttacagacca ggtgtaatgg aaaagttagg tctgggttat gatgagttgg
    45541 ctaaagttaa caatcaaata atttatggag ctgtatcagg atttggatgt tatggaccat
    45601 attcagaacg tccaggttat gatattattg cacaggcaat gggtggtctt atgagtataa
    45661 cagggcaaga aggaggagaa ccaacgagag ttggtaatgc tatgggtgat gtactaggtg
    45721 gaatgaattt aactattggt atactcacag cactcaacgc tagaaaaata ataggaaaag
    45781 gacaaagagt agatgtttcc ctcgttgatt ctgttgtatc gtctctcgaa actggtatac
    45841 agagatactt tgattcagga caacctgaac ttatgggtaa tagatatgct tcagcctatc
    45901 cttatgactc ttttaaggca agtgatggaa gttttgtaat aggctgtggt aatgacaaac
    45961 tttttgaaaa gttatgtaaa aaagttcttt ttagagaaga ccttttaata gatgagagat
    46021 ttaaaacaaa tcttaatcgt tgtgaacatt acaaggctct taaaccagaa atagaaaaat
    46081 ggtctattaa gcatacaata aaagaagcag ttgacttaat atcagaggct ggagttcctg
    46141 ctgctcctat ctataatctt gattgtgtta caacagatga acatatagca aaagcaagag
    46201 aaatgattgt agatattagt catcctatta taggaaatat gaaagtcaat ggaaatccag
    46261 ttaagttgat gacaacaaaa gctaaaattg atatgccagc accatctcta ggggaaagta
    46321 acgaggagat ttataatggt tggcttggtt ttgatagtga taaaataaaa gatttaaaag
    46381 aaaatggagt tatttgatta aaaaatagct aaacacactt gtgactttag tcaggggagg
    46441 ttcagttaga ataatatcaa aaaatattaa atcaatactg taaatcaaat atagaattgt
    46501 cagaagcatt taagatggga aaagctactt agacattgag tctttgtggc ttttcctatt
    46561 ttcattaaga attttatatt atcagaatag atatgtacta aactaaagta ttaacaattt
    46621 aaattaatag aaaataaact acctaattat gttgaataaa gactacttta gtgaaaataa
    46681 acttatagag atgctattta aattatttta atggaaatat caaaaatgag actgcattct
    46741 caaaaatgag actgcgtttt ttaagtattt tctcgaaaat gagacaaaaa tattgtttta
    46801 tgggttttat tgaagaaaaa ttcttctgtg aattacaatt taatcaattt taaagttgaa
    46861 aattattaaa aatttagtga aatttatgta tatttcgttt attttattaa aaataacaat
    46921 tttttactaa aaataaagaa cttcaatggt gattggcata gtacttgcta ttttatatta
    46981 acaagaaatg tagaaaaaat aacaatgtat aatgggggga atatgatgga atctgtaatg
    47041 gaaaatttga acaatcttaa ggtggaggtt aaggacaaag tctgtgttat tactataaat
    47101 agacctaaag ctttaaatgc tcttaatagt gacactctta gggaactatc acaagttatt
    47161 gatgtagtat cagaaaatga ggcaatatta ggagttatta ttactggaga aggtaaagtt
    47221 tttgtagccg gtgctgatat acgccagatg caaaactata aaagtgagga aggcagaaaa
    47281 tatgcaggtt atgctcaggg agtttttgat aaaattgaag ctcttgaaaa aacagtaata
    47341 gcagcagtta atggatatgc attaggtggt ggatgtgaac ttgctatgag ttgtgatatt
    47401 agaattgcat cagaaaaggc tatatttgga caacctgaag ttaatttagg agttattcca
    47461 tgttttggtg gaactcaaag attatcaaga cttgttggaa ctggaatagc taaagagtta
    47521 atttttacag ggagacaagt aaatgcagaa gaagctaaat ctattgggct tattaataaa
    47581 gtggttccaa gtgatttact tttagaagag tctatgaaga tgatgaacca aatagttgaa
    47641 aaagcgccaa tagcaataag atatgcaaaa gttgttatta acaaagggat agatatggat
    47701 ttaaagaatg ctcttgaact agagaaagat attgcaggtt taacttttgc tacaagagat
    47761 aagcaagaag gaatgaatgc atttatagaa aagagaaagc cagtttttga aaataagtag
    47821 ctattataac taaaattgga acaatgtaga atatattcaa aatctaaatt tcgtgaaaaa
    47881 atacatatag tttaatttta aaaggagtta atttatgaat acgggagtaa ttataagttt
    47941 agtagggatt atcatagctc tatctcttct agttgtaatg gttatgaagg gaataaatat
    48001 ttttattata gcaattgtat gttcatcatt agttgctata acaggaagcc taaatgtgta
    48061 tgatgcactt aaagtggatt atatgacagg gtttgttgga tttcttcagg caaatttctt
    48121 tattttccta acagggacat taatgggaaa aataatggag attactggtg gagcaaaatc
    48181 tattgctaag atgattgtaa gatggattgg gaaggataaa gcactacttt ctattccaat
    48241 agcttgtgga atattagcct atggtggagt aagtgttttc gttgtaagtt ttgcagtgtt
    48301 tccgatagct ttagaaattt ttaaagaagc tgatttgcca cgaagattta taccagcagc
    48361 tttgactttt ggatgctcaa cttttgctat ggttgcacca ggggcaccac aaattcagaa
    48421 tattgttcca gcatcaacat tagggacaga tattatggct ggagcagtaa atggttttat
    48481 atcatgtgca gtaatgttta tagttggaag tacaattttg tacaaaatgg tttcaaaaga
    48541 aaaagccaat ggtggtcatt ttatagcaca tgaatcagat atatttgatg aagcagaagc
    48601 aactaattct aagagagaaa atggtcccaa tggtgtaatt gccttaattc cattgatagt
    48661 gtcaatttta ataattaatg taaaagttaa tggaaaagcg atagtaccaa ttgaggtggg
    48721 agtatttatt ggagctttat tagtatattt attgttaaat aaatatcaag ataatactaa
    48781 aatagttgga catgttggtg atgcatgtaa aactacagta gtagcaatat gtaatacttg
    48841 tgctgtagtt gcatttggtt cagtagtaaa atcagcagtt ggttttgact tcatagttaa
    48901 tgctatgact aatattcctg gtcctcctat tgcaggggct gcagttggaa ctacagttat
    48961 tgcaggtatt tgtgggtcag cttcaggtgg actaggaatt gcagctccac ttcttggacc
    49021 agtattttta gccaagggtg tttccgctgc agcattaact aggactatgg caatttcatc
    49081 agcagcatta gattcacttc cacacaatgg atatattgtt actgtaacaa atggtctttg
    49141 taaagaaaca cataaggatg cctatatgcc aatattctgg gtaactgttt taaccccatt
    49201 tattggaacc atagtagcag tcctactgtt tacaatgttc ccgggattgc cataagagaa
    49261 aagataaaag gtataaatta tattttgatg ttataaaatc aattttcaaa atatatacaa
    49321 taaatttcat gttttaatac tgtaaatatg tatttaaaat aacaaattga ccatataagg
    49381 aggaattgaa agtgttaaat aaaccattag agggagttaa ggttattgac ctaacgtatt
    49441 ttgtagcagg tccagggact tctaaaatat tagctgactg gggtgctgac gttattaagg
    49501 tagagccaag ctttggagac ccaggaagaa agacaggggc aacaatgaca atgccaatag
    49561 atgattataa taatcctttt tacagcacat ataattcaaa taaaagaggt ttgtctataa
    49621 atcttaagag tgaaactgga attgaaatta tggataagct tttaagcgaa gcaaacgtat
    49681 ttgtttcaag ttatagaaca ggagcattaa aaagactagg tcttgattat gaatcattaa
    49741 gtaaaaagca tccacacctt atctggggtc agataaatgg ttttggcgat tttggacctg
    49801 ctaaggataa tgcaggattt gatacagttg ccttttgggc aagaagtggg gctatgcttg
    49861 atatagcaga aaaagataca agtccaataa atccacctat agcctttgga gatgcaacaa
    49921 cttcttgtag tttatctgga ggaatatgtg cagctttgta ccagcaagct aagactggaa
    49981 aaggacaaaa agtaatggca tctttatttg ggcaagcaat atggaatgca tcatctttat
    50041 tagcatctac acagtttagt gatgagtatc caaaaactag aaaaaatgct atttcaccag
    50101 taataaattc ttatcgttgt aaggatggaa agtggatatt cttaagtatt ttagagcatg
    50161 aaagatattt tgaggcactt tgtagattat ttggaagaga agacttaata aaagaagaga
    50221 aatttgcatc ttcagtagaa agtaagaaaa atgctacaga acttattaat attttagatg
    50281 gtgaatttgc aaagtttact caaaatgaga tggttgaaaa acttactgct gctgatatag
    50341 ctcatgaaaa aattcaacat gttaatgatg tagtgactga tgaacaggct attgctaata
    50401 actatatata tgaacataca agtaaagatg gaaataagac aatgcttgca tctactccag
    50461 ttaaatttgg aaatattgaa gttaacatga cttgtgatgc tccacttata ggagaacatt
    50521 cagatgagat attgagagaa cttggataca gtgattctga tatagaggct ctaattgaat
    50581 ctggaattgt aacaatgaat aaagaagcat gtgaaatatg ttaataaaca tgtgaagtat
    50641 gttaataaat aggagggaat tttatggatt ttagattaac agaagcacaa ttaatgcttc
    50701 aaagagtagc aaaagaattt gcagagaatg aaatagcacc aatagctgct gaaacagata
    50761 aaacaggtat ttttccaagg gagcttttta gcaaaatggc taaaatagga tttaatggaa
    50821 ttggaacacc tgtagagtat agtggttctg gtggggcaga tatagaaaag gtaattgttg
    50881 ttactgagat tgccaaaaaa tgtgcagcat ctgcagcaat attatcaata cacacaatat
    50941 atgctcaagc tattttgaaa tttggtactg aggaacaaaa gaaaaaatac cttccaatga
    51001 tggctgaagg tgggtgtgta ggtgcttttg ccttaaccga acctaatgct ggttcagatg
    51061 ctgcgagagc tgcaacaact gcaattattg atgaagaaac tgatgaatat gttttaaatg
    51121 gaactaagtg ttttatttct ggtggaggtc aagcagaatc attaataata tttgcattga
    51181 cagacccatc aaagggaata aagggaatgt ctgctatcat tgtcgacaaa ggtacgccag
    51241 gtttttcaat aggaaaaatt gaagaaaaaa tgggtattca tggttcagaa actgcagagt
    51301 taatatttga taactgtaga gttccaaagt ctaacttatt aggaaaagaa ggtaaaggat
    51361 ttaatatagc tatgacttgt ttagatggag caagaattgg agttggagct caagctgtag
    51421 gaattgctga aggggcttta gaagaaagta tcaaatattc taaagaaaga gtccagtttg
    51481 gcaagccaat ttcagctttg caaggtattc aatggtatat agcagatatg gcgacaatgg
    51541 tggaatcagc aaaattatta gtatattatg ctgcagattt gaaagctaga ggagaaaaac
    51601 acactaaaga agctgctatg gcaaaataca atgcgtcacg tactgcaaga gaggttacaa
    51661 atttagccct tcaaatccat ggtggatatg gatatatgaa ggattatcca ttagagagaa
    51721 tgtacagaga tgccaaaata acagaaattt acgaaggtac ttcagaaata cacaaagttg
    51781 ttatttcaag agcagtacta ggataggagg aaaagaatga atatagttgt ttgcttaaag
    51841 caagttccag atactaatga agttaaaata aataaagaga caggtactct aataagagat
    51901 ggtgtaccaa gtataatcaa tccagatgat agaaatgctt tagaagaagc tctaaaaatg
    51961 aaagatgaac taggagcagt gattaaggtt ataagcatgg gacctcctca agctaaaagt
    52021 gctttaaaag aagctttggc aatgggagct gatgaagctt atttaatctc agatagagct
    52081 tttggtggtt cagatacttg ggctacatct acaattattg ctgctgctat agagaaggtt
    52141 ggaaagtatg atgtaatatt ctgcggaaga caagctatag atggagatac agctcaggtt
    52201 ggaccagagg ttgcagaatt tttagggata ccacaagtta cttatgcgaa agaagtaaag
    52261 gttcaagatg acaaattact agtaactcgt tatacagaga caggggatta tttaatagaa
    52321 gcaaagatgc cagttttatt aactgctata aaagagttaa acaatccaag atatccaagt
    52381 gtcaagggaa tcttagaagc ttataataat ggagatgcaa agattactgt attaacactt
    52441 gcagatttag atgttgatac aactcaaatt ggattaaagg gttcacctac aaacgtttat
    52501 aagtcttttg taccagttaa agacaagcat aatgaaataa tagaaggtat aaataaaaaa
    52561 gaaaaagctg agaaactaat agaaatacta ttcgatttga aactagtata ggagtgttaa
    52621 gatgatgaga gcaaaagtta atcaaggtat aaatttaaat gattataatg gtgtttgggt
    52681 aataggagag caaagggaag gtaaaattaa tcctgttacg atagaactta ttggtgaagg
    52741 aagaaagctt gctgaccaat taggaaaaga gcttgcagtt gtgatagctg gatatgaagt
    52801 agagaaagaa gtgaaggaat tacttcacta tagtgttgat aaagtatatt acatcaatga
    52861 ccctcttctt aaagatttca ctactgatgg atatgcaatt tcaattgcaa atttaatcga
    52921 aagaaaaaag ccagaggttg tattggttgg tgctacttct ataggaagag atatagcgcc
    52981 tagaattgca ggtaaggttg gaacaggtct aactgctgac tgtacaaaac ttgaaataga
    53041 ttcaacagat aataagttat tacaaacaag accagcattt ggtggaaatt taatggccac
    53101 tattgtttgt ccaaaaaata gaccacagat gtcaacagtt cgtccaggag ttatggcaaa
    53161 agctgtaaga aacgaatcag agactggaat tttagaagtt gttactccag aacttactga
    53221 aaaaatgatt agaactagat tagtagagat acttccacaa gaaaagaaat ctgtaaatct
    53281 aactgatgct agaataatag tatcaggagg aagaggatta aaaagagcag aaggatttga
    53341 gcttataaaa gaattggctg ataaattggg ggcagagatt ggtgcttcaa gagcagcagt
    53401 agattcaggg tggatagaac attctcatca agtgggacaa acaggaacta ctgttagacc
    53461 agaactatac attgcatgtg gaatatctgg agcaatacaa catttagcag gtatgagtga
    53521 ttctaaatat atagttgcta taaataaaga tgcaaaagcc cctattttta gtatatgtga
    53581 ctatggaata gtaggagatt tatatgaaat tatacctgaa atgatagaat cattaaatag
    53641 gtaactttta gaaaacattg aatatgtaga atgataagtc ttataatatt gtattgtaag
    53701 acttattatt tttgctgaag gttatagtgg ggagatgaaa caatgaaaga gcagtggtat
    53761 aaggatatat ttgcaagagt attatctatg actgatgatg gttttattgt tgtaaataga
    53821 agtggagtaa taatagatat taatgataaa tattgtgact ttttaggaaa agaaagaaaa
    53881 gatataatag gacaaaatat acaaagtatt ataccaaata caaaaatgct agatgttatg
    53941 aaaaataagt attgtgaaga aggagctata catcattatt caggtggaaa tacaaaagaa
    54001 aaaagtgtaa tagtaagtag gtcttatgtg gaaaatgaca atggagaagt agttgcagga
    54061 gtagctcaag ttaaatttag attgcaatca tttgatgtag ctaaaaagtt aatgtcagaa
    54121 tatatggagc tccaatatta taaagagcag tttaaggata actgtggttt tgacaagctc
    54181 ataggtgaaa atagagactt catagaactt aagaaaacag gtgtgaaagc ttctaaaaca
    54241 aactttccag tacttttaac gggtgaaaca ggtacaggaa aagaagtctt tgctagagca
    54301 attcacaata atagcagtag gtcagataaa cctatggtta gtataaactg cgctgcaata
    54361 ccagaagaat tattagagtc agagctattt ggctatgacg aaggagcttt tacaggagca
    54421 aaaaagggtg gtaaaaaagg taaattttta gttgcgaata atggtacaat ctttttagac
    54481 gagataggtg acatgccttt gaccatgcaa gcaaaacttt taagagttct tcaggaaagt
    54541 gagatagaac cagtgggagg tcttaaaact ataaagatag atgtaagagt aatctctgcc
    54601 acaagaaaga atttaagtaa aatggttgaa gagggattat ttagagaaga cctatactat
    54661 agattaaatg taataaacat tcatatgatg gaattgaagg acaggcaaga tgatatttta
    54721 ttgctagcaa attatatatt aaacaaatta aatgttgaat acaaggaatt gaaggtttta
    54781 agtgataagg ttaaaaattg ttttattaac tatacttggc cgggaaatat aagagaacta
    54841 caaaatgtaa taaaaagtgc ctatgctgta agtgatgata tggtcattat gatgtgtgac
    54901 cttccatcta agatggataa tatcagcaga gtagctcaat gtaatgtgga tagcaattgt
    54961 tcaattcatg aaatggttga gaattatgaa aagagcttaa ttattgatgt gttaaggaag
    55021 tataattgga aatgttctaa ggcagcagag gttatgggaa tacacaagag tcttttatat
    55081 aagaaaataa aaaagtatga aattgaatta aataattaag ataaattgaa ttaaggcaat
    55141 gctaaaaaaa cgcccttatt caaagcgaac tgtataaact gttttatgca gttaaaacgt
    55201 gtaaaagtag atgtgaagta ctaatgtcaa tcattagtac ttttttatta tatttataat
    55261 tactatctat atttcagtat cttttgatat ctaagattat tatgtttaat ttaggatata
    55321 acaaaaccct cttagttatg gacagttttt tatattttaa ctgtctacta agaggggata
    55381 gtttagttta aatttagagt aaattttatc tagcatttat aaaaaatatt ttgaatagct
    55441 tttttgttat ttaatcataa ttttctactt ctttatcaag ttctttgcca caagaatcac
    55501 acttatatat agcattgtat ccgtaatcat attcatcaac tattttcttt tgtctaaata
    55561 caccaccaca ctcacatagg aaaccaattt ttataagtgt aacgataaat tgtgatttta
    55621 taaattttat atcattacat ttatcgttag tgtaaaatgt ataaatataa gagttatcgc
    55681 actcatctct taattcaaat ctttcaatat atgtgttatt ttttaattcc tcaaattctt
    55741 ctttagttaa atatgatttt tgttgcaatt catgtaaacg cttaatttgg tccattattt
    55801 atatcctccc aataatttta gtattttaag cttagataag gaatctaagt tttattaaat
    55861 ttatcccaag gaattattta aatcatattt agttttatta attacaacat atataaatta
    55921 cacgaaaata aaactaattg taaaaataat atcctgtgaa aacctaaact actaacccct
    55981 tactaacccg aaaactaaaa aaagaaaata tatccaaata taagtgatat ataaataaag
    56041 atgtttcata taaatttaac tttaaatatt ctgacaataa tatatataaa tatattatag
    56101 ttaaaatata ccacatattt tgggtattgt atactggaat tagagtaatt aatttatttt
    56161 ttaacataca aatgatttta tgaaaaaaaa caagactcaa aaatttttat attctttgat
    56221 agaataaaat tgagagtaaa tttattgaat tttataaaat ttataagggg tgagtctaag
    56281 atatgcatga agataaaaat gatatatttg aatcaataga tactgaggat tttgataata
    56341 aaacagaaga agaatgttta gagctagtaa gaaaaaatgg attgaattta atatacataa
    56401 aaaatcaaac agaagagata tgtctagagg ctgttagaca aaattgtaat gcaataaaat
    56461 gtgttcagaa tcagacagaa aaaatatgta tagaagcagt taaacaagat tggagaatgt
    56521 tagaatttgt agaagagcca acagaagaaa tttgcatgtt ggctattaac caagatggaa
    56581 cagcattaaa atatatagaa aatcagacag aggagttatg cttaagagcc gttgaaaaaa
    56641 atggtgcagc tttggagtat gtaaaagaac aaacagaaga aatatgtata gaagcagtta
    56701 gaaacagcga atttggattg gcaagagtga aaaatcaaac agaaaaaata tgtatggaag
    56761 cagttaagca ttgtagctat aatctaaaat gggtagaaaa tcaaacagaa gaaatatgta
    56821 tggaagcagt gagacaaaat gggcttgatt tgaaatttgt aaaaaatcaa acagaaacaa
    56881 tctgtttaag agcagtaaga caaaatggaa tggcattaga atttgtaaag gaacagactg
    56941 ttggtatatg cttaaaggca gtaagacaat atggaatggc attaaaattt gtaaaagaac
    57001 aaacagaaga aatttgtaca gaagctataa aacaagataa aagagcactt agttttgtaa
    57061 aaggagataa ggaaaaatac aaggctctat atgataataa tgaaccattt gcaaagagat
    57121 atgttagaaa tgtaatagaa aaagaaaaca gagcattgat taaaaaagga gaagaaaatg
    57181 caaaaatcaa aattgcagga aaactttatg atagaggcat gtcttttgaa gatatatcag
    57241 atatagttga gattgaaata agcaagttaa aagtgagttt aggtgttttt taagggaaat
    57301 agttaataaa aaaataatcg actagctctt tgtaggacag caaaattagt gatataattt
    57361 gatgtataat aaattatttt tattagataa gggggaatta aagttgaaga ttacagtatt
    57421 ataccaaaca agaagtggaa acacagaaag ggtcgctaag ctgatagaag agggcgctaa
    57481 aaaggtggat ggagtagatg taaagcttat gagacttgat aatattgatt tagattattt
    57541 aaatgaaagt aaagcagtaa tatttggaac acctacttat ttagcaaata caacttggga
    57601 agtaaaaaaa tggtttgatg aagattcaaa aaaagttaat ttagctggaa aattaggagc
    57661 tgtttttgct acatgtgatt atatatgtgg aggtccagat gttgcgatac ttactatagt
    57721 aggacatttg atggttaaag ggatgcttgt gtattctgga ggtggttctt taggaaagcc
    57781 atttatacat ttaggacatg tacattcaat tgaaggtcca gagttacaag atgagaaggc
    57841 tataatattt ggtgaaagaa ttgctactaa ggcaaaagaa ctatttgctt aatttctata
    57901 tgcataataa tgattagagt aaatttaggg ttttaatgga gatttgaagt aaaagttata
    57961 aaataaaaaa ttttccataa aattactcaa gatgaattat aatataatta taaataaatt
    58021 atattattaa aatatttaaa atcaaacgtc aatagcgagg gaagtttatg gtatggcata
    58081 tagaatatga gattttttct gcaattatag ttattttttt aatggtatac ttttttagaa
    58141 gtaaatttat acctacttta caaaacaaaa tatattgtgc acttttaata ttctcatttt
    58201 tatttataat ttcaaatatt ttaggttcat tttgtctaaa taatatagac aaaattccaa
    58261 tttttattac ttttttattg aatcagatat acttattgtt attgccaata ccagcagcac
    58321 ttgtatcatt ttatgttatg gctattattt atcaagatat aaggtatatg aaaaaaagat
    58381 tattattttt atctatacca cttataattt gtataatctt atctattaca aatcctttta
    58441 cgcatattct atttggattg tcaaaagaaa caggttatat acgaggttgt ggatatgttg
    58501 caacttttgc atcttttttc ttttatgcaa tatattcagc atttttatct tttaaatata
    58561 gaaaagcaat gcatgaatca aaaatatggg ctattagagg ttttcttata gtttcaattg
    58621 tggcaattat cttacaggca atttttttac agtatcttct tacaggaact gcatgtgcat
    58681 gtagtttact tttgacatat ctttctatgc agaatcgagg tcttattatt gatgacctta
    58741 ctggtgtact caatagacaa tcttttattc aagagctaga tttgaatatc aatactgaac
    58801 aatcaggatt tattattaca attgcgcttg atgattttaa gtttatgaat gaaacttttg
    58861 gaacaaaaaa tggagatatt gcactaaaag aagttggaaa atatttgatt cagatacatg
    58921 atgtaaacca tgtatataga atagggggag atatattttc tattgttgtc aatagtcaat
    58981 taggtataga accagatgat attatcagaa agatagaaga aagatttaaa aagccttggc
    59041 tagtagaaga gataagtttt aatttagcaa ctagtattgc tgttgtttat tacccagaaa
    59101 atgcagaaac gacagaagat gtaattgttg ctatagattt ctctatacat gaagcaaaac
    59161 gttctgagtc aaggcgagtt gtttatgcag atgcgtctat aagtgaaaag ataaagaaga
    59221 aacatgttat taaaaattgt ttaaaagaag cattaaaaaa tgatgggttt gaagtgtact
    59281 accaacctat attttctaat agcaggggca ggtttacttc agcagaggca ttacttaggc
    59341 tagaacacaa agagttaggt tttatacctc ctgatgaatt tattccaatt gcagaacaaa
    59401 caggattgat taactcaatt ggattagtag tctttgagaa ggtatgtaga tttatagcta
    59461 gtgatgagtt tgaagattta aaattggata atatagctgt gaatctttct gtagtacaat
    59521 gtatgcaaaa aaacttagct gatgatttac tttatcttat gaataaatat aatgtatcac
    59581 caactaaatt taaacttgaa attactgaga ctgtggctat gggctctttt aatataatta
    59641 aagaaacaat ggaaagatta attgatttag gtgttaagtt tgcacttgat gattttggaa
    59701 ttgcttattc tggagttact aatatgcttt ctttaccatt ttcagtaatt aagttagata
    59761 agagtttgat ttggtctatg aatgaagata gtaggcataa acttacagtt gagacgatta
    59821 tagctcttat aaataaattg aatatgaagg ctgtagcaga aggtgttgaa accattaagt
    59881 gtgctgaaga tttaatagct atggagtgtg aatatttgca agggtattat ttttctaaac
    59941 cagttccaga agatgttttt aaaaatttgt tgaaagaaaa tacttttaca agttaacacc
    60001 ctttattttt ttaattacaa ctttgttcat tgacactgcc agcgatatat tataaaatta
    60061 acacaataat aaatattaaa tttattatac atattattaa tattaattaa tggagtaaag
    60121 atttattata tattttattt aattatccta aagtgagaaa ggaagatgtg acatgaataa
    60181 aaagaaaata ttagtgccaa ttgatgggac agaaagaagt atgcattctt tggaatttat
    60241 aaaaggaata tttaaaaaag atgaagttga agtagaaata atgaatgtaa aagaactagt
    60301 atttattgat ggcatatccc tggctgaaga gataaaaaat tctgaaaatt taggaagaag
    60361 aatcttggat aaagcagcag agataatggg agagtatgat gttaaagtac attttacttt
    60421 tggatatcca ggagatgaga taattagaaa agcaaaagaa gataatgtag attttatagt
    60481 tatgacaaaa tctactaaaa aaggtcttac aagaatgata ggttcagtaa cagcaagtgt
    60541 agttaaacaa gcaaaatgta tagtgatgat tgtaccggag tagaattaga aaggtatttg
    60601 aaatatgaat aaaaagatag tagcagtttg tgaaagtgaa agaagtttaa attctcttaa
    60661 gacagctgca aatgatttag gatttgattt agtttatgaa attcaagaaa atgataatat
    60721 aaaaaatgaa ctttctattt atgatataga agatgcatcc atagtgttat ttgttacaag
    60781 tgattctata gaaagcatag agaagattga tagatttata gatagagaat tttatgaagt
    60841 tgatccaaag tatataatag aggatgcaaa atctatagta agtgaaattt taatagactt
    60901 aaattaatcg tgggtgtcgc actaagaata gagcgacgcc tttttatata ttttacacaa
    60961 gaaataaaga ggttgtatca aaatatagat aagagtcttt ttcattgttg aaatgatgaa
    61021 aatatatttg atttcataca aaaaagagta cctcataact aaaaagttca ctttgagaca
    61081 ctccattttt atatgttagt tgcatttaag gtaaaataga agtttaatca tgttgaaata
    61141 actgaattac atcttctaaa tgattgtaca ttgatgtata acctaagtaa gagtctttac
    61201 tatcaaatgc aatcattatc ttgttatggt ggctaatcat atccttgaga gaatttctat
    61261 atttaaaacc aaagtattgg ttagaagaaa ctgttttagg tattaactca taatatttta
    61321 taaaaattgg attatgagaa gctaaaatta tctctttgtg aaattgcaag tcagcatcat
    61381 aacattcttc tatcaaaccg tgagaaacct tatccaattc ttctattgac tttaggtaag
    61441 tatattttat tttttgaagt tctttagatg tagcatttaa aattgctagt ttagtagctt
    61501 cactttcgat aagttgtctt gctcttaaag attctacata aaattcttgt atgttatgat
    61561 ttttatagat ttcaccatca tcaaataggt caactttttt aaatccttca actataggac
    61621 ttgaataagg cacagctcta agtattcctt ccttacagag tatatttatg gcatttctta
    61681 caggtattct acttatgtta aataggtcag caatctttct ctcacttggt aatttactat
    61741 taattttaaa agttccattt agaatgttta atttaatata atcaataatt ttttcagtgg
    61801 catttaagct tttcataaaa actcctaaac atataatttt tttatgattg tattatatca
    61861 tagttaagag ttaaatctac ttttttataa tatgtataag acaggataga ggccaaaata
    61921 gctataatag ccaagataaa gtatccatat tgtattgaag tatattccga tattttacca
    61981 actatcattg gaaatacaga cattcctata gcataaattg cttgaaaaaa acccattgca
    62041 gtagatttct gatgttttgg tacatttttc atagactcgc tagtaaggta agaaaggagt
    62101 atacctgtag atatacctgg tagtacttgt agtacaaata ttatattaat attttttatt
    62161 gttggaacta aaaagcaata ggctgaaact aaaataaaaa ctaaaggaat ccaaaatttt
    62221 ggcccatact tagtacaaaa tttagtagaa gcaaagccag aagaagcaac agcacacacc
    62281 atgtaaaata tagaagatag acctatgagg gtagaactag aacctaagtt tttaagaatt
    62341 tgagtagtaa atgacattgt tgtagacatt tgaataccct gttgaattaa tgccataaag
    62401 gaaaaaaata caagtctttt atccttgcag atagataaat attttttaat tgatattttt
    62461 tcaggtattt tttttgaatt atgatttttt atatttaagg ctagaatcgt tccaataact
    62521 gaagacaata cactcatgat acataaggct gtcattccta atttttcata aaataaagta
    62581 ctcataacaa atccaatcaa cattcctaga ttgtttacta atattattgt acttgtagct
    62641 ttttgttgat gttctgtaga aaaaaagttg gtatagtgaa ccatgtaaga aatccaagtt
    62701 gatgatgata ttccagataa aatgttagct ataagaaaac cattgcctcc aggagaaaag
    62761 actcttataa gagatgctaa accagcaaag aaaattccag acagtataaa tattttatgt
    62821 ttatttatgg aatcagcaaa tactccaaca ggaagcctta ataaacattg tgagattcca
    62881 tatgcaccta ttattatacc aatcatattt gtagatacat tacatgcact taaatatgga
    62941 ttttggaaag gtatatatac atattgtgaa aaccagaaaa atgtaacaat agaaagtaaa
    63001 agtaattttt gattagatat ttttttcata ttatcctccg tatggtattt ttataatgca
    63061 aataatatac catttggatt ttttaatcaa gtactttctc tattaaaaaa aatttaaata
    63121 tataattatt atttacaaaa aaattatact ttatagttga attaagaaaa cgcttatgat
    63181 actataaagt taacaaattt gaatatataa cagtagacgt gttactggta atgcaggcaa
    63241 gatcgaatca atttttatag attatctata gagtactatg ggtataatct atttatttgg
    63301 ttcgattttt ttgtttaatt ggccataaaa caaaaagcct atagttgaaa atggaggatt
    63361 ttttatggat tataaaaata tagctcaaga aattctacta aatgtaggag gaaaagagaa
    63421 tgtaaatgaa gtgactcatt gtatgacaag acttagattt aaagtcaaaa gcgcttctaa
    63481 agtgaataag gataaattat ctaaaactga aggagtaata actgttgttg agagtatggg
    63541 tcaaatacaa gttgtaattg gaaataaagt aaaaaaagta tatgatgagg ttataaaaat
    63601 tgtacctcaa tcaaataacg taggtaaaaa gaatgaaagt caagaaaagc aaggtataat
    63661 taattctata ttatcagcag tagctggtat atttacacct acaatacctg ctatagcagg
    63721 ggttggtatg attaaaggta ttttatcagt tcttgctatg tattatatga ataaaaatgg
    63781 agtagatata aaagaaacgc aaagctatat tatcttaaat gccatggctg attctatatt
    63841 ctattttatg cctattatac taggatatac tgcggctaaa gtatttaatg caaataaaat
    63901 aatatctatg gtattaggag ctacactttg ttatccaact tttactgctt tgatggcagg
    63961 tgaagaatct gttagatttt taggattggc agtaacaaaa gctacgtata catcatctgt
    64021 tattccaata attattgcta tatgggctct ttcatacgtt gaaaaagtat tagaaaagta
    64081 tatacctgag gtaattaaaa taataatggt tccaacttta tcattggtag taatgttacc
    64141 tgcaacatta tttttatttg gaccaatcgg aatttatata ggaaatgtca taaacttttc
    64201 ttataagtat atttatgaat taagcccagc attgtgtgga gcatttgtag gtgggttatg
    64261 gtgtgtgttg gttatatttg gtgctcatag agcattatta ccaataggta taagtgatgt
    64321 tgctcaaaca ggaagacaga atttattggc atttgcagga gctgcaaact tttcacaagc
    64381 aggggctgct ctaggagtat tctttaaaac taaaaatcaa ggactaaaaa caatttctat
    64441 gtctgcaact ataacagctt tatttggtat aactgaacct gcaatatacg gtgccaatct
    64501 tagattaaaa aagcctatgg tatgtgccgt aatatgtggt gcatttggag gtgcgataat
    64561 gggaatgggt ggagcttatg gtaatgcatt tgcaaaccaa ggtgttttaa ctatacctgt
    64621 atatgctgaa gcaggtgcat taggtttctt aagttatcta ggtggttgtg ctatagcatt
    64681 ttttggttca gctatttcaa cttatctagt tggatttgaa gatttggaag agtcttctaa
    64741 taaggaaaat tcatctataa aagtagaaac gaaggatggt gttattgata taacttcacc
    64801 tgtagagggc gaatgtatag aattgtcaga agtaaaggat gatgtatttg cttcaaaagc
    64861 tatgggagaa ggtatagctg tgttacctac aaaaggagta ataacagccc ctactgattg
    64921 tgaagtagct tctttatttc caacattaca tgcaatagga ttaaaattag ataatggagc
    64981 agaaatgtta atacatgttg gaatcaatac agtagagtta aatggtaaat actttaccaa
    65041 acatgttaat caaggagatt tagtgaaaaa aggtgataaa cttatatcgt ttgatataga
    65101 taaaataaaa aaggttggtt atgatgtaac tacgccagtt atagtaaaca atacatttga
    65161 ttttgggcaa gtagtttctt gtaaatctag ttatgtttca accaatgata atataatttc
    65221 attagtatta gctggtaatt aagttaattt gactagagat aagtaaattg atttaaaagg
    65281 aaataagtaa atcaacaatt aaatacatct aaaagtaagt ttattgcaat gaattgttaa
    65341 agaaaataat taatatggag taaatctatt gcaatgaagt aacaaagaaa ataattaata
    65401 tagagtaagt ttattgtaat gaattgttaa agaaaataat taatataggg taaatctatt
    65461 tcaatgaaat aacaaagaaa agagttaata tagagtgaac ttattgcaat gaatcaacaa
    65521 agaaaataat taataaaaag gagaaatatt tatgaataca ggatttccaa aagacttttt
    65581 atggggagca tcatcttctg catttcaagt ggaaggagct tgggataaag acaataaagg
    65641 aaaaaccgta gccgactata attcttttaa aaagtctcat ttacaggcag atactaaagt
    65701 cgcatcagac ttttaccata attatgaaga agatattgaa ttaatgaaag aattagggat
    65761 gaaaacatat cgtttttcaa tttcatgggc aaggataata ccagatggtg aaggagagat
    65821 aaaccagaaa ggtttagact tttataataa gataatagac aaactaatag agtgtgatat
    65881 tgagccattc gtgactttat accattttga ccttccattt aaattagtag agaaatataa
    65941 tggttgggaa agtagagaaa ctgtctatgc ttttgaaaga tttgctaaaa tatgctttaa
    66001 gcattttgga gatagggtaa agtattggca acctcataat gaacagaatt taattgttag
    66061 agtggaggag agaattaata tatatgatga aacagattca tggaagatag ataaaatgcg
    66121 tgctcagatg gattataatc tttgcttagc acatgcatta gcagtcaatg catgtcatga
    66181 gatgataaaa gaaagtaaaa ttggagcagc agtatcatca tctgtaacat atcctcttac
    66241 ttctaagcca gaagatatat atgcagctag aatgaatgat aattttaaag tgtactatat
    66301 gcttgatatg catcattatg gagaatatcc agggtattat atgaagtatc ttgaaaaaag
    66361 aaatatagtt cctcacatgg aagatgggga taaagagata cttaaaaaag ctaaaatgga
    66421 ttttatagct gtaaattatt ataggacaaa ttgtgcagaa gctttacctg aagattcaca
    66481 acatccattt ggattaagag aaggaactgt tgattttagt atgtatggac tatttaaaat
    66541 gtcaatgaat cctaacttag aggcttctga gtatggagca gcaatagacc catcaggtct
    66601 tagagttgcc ttaaatgaat attggcaaag atatcactta cctgttataa taacagaaaa
    66661 tggtctagga gctaaagata tattagaaga tggaaaaatt catgatgact atcgtataga
    66721 ctatttaaga agtcatataa atgcatgtaa actagctatt gaagatggtg tagagatgat
    66781 tggatattgt ccatggtcat ttacagacct tttaagttct tctcaaggtt ttaataagcg
    66841 ttatggactt gtttatataa atagaactga ccatgaaatt ttagatttaa aaagaatcaa
    66901 gaaagatagt ttttactggt ataaagaagt tatagagaac aatggaatag taaaataaac
    66961 ataaatatat attgagggtt ttagtatgta cattacaaag gtattaaata attcgttgct
    67021 acttgcaaag gatgataatg atgaagaaat aatattgatg gggaaaggca ttggccataa
    67081 ttataaggcc gggtctgagt taaatgaaaa agatatagaa aagatttttg ttcttcatga
    67141 tgaaaatata aaaaagagta ttatacaatt ggcaacagaa atagatgcag aatattttgg
    67201 tatagctcaa atgataattg catatggaat agaaaaatat aacttaaaac ttatgaacca
    67261 tatatatttg gccttaactg accacattgc ctttgcagtg agacgtttta aagaaggtat
    67321 aatgattgaa aatcactatt tgttcgaaat caaggaattt aatccaaaag agtatgatat
    67381 aggaaaatat gctattactg tttttaagga ggttcttggt ttagacctac cagaagaaga
    67441 gattggtaat atagcaggcc attttataaa tgcacaacaa gataatcctt atagtgatag
    67501 aaataagaga agtgctaaaa ttgtaaatgc tattttgcaa atagttcatt atcacttttc
    67561 tattgtatat aataaagagt cattttatta taggagattt gtaatgcatc taaaggcctt
    67621 ttcacaaaga tttctggcta atgaaccatc aagagaaaaa atagatttta tatatgagca
    67681 agttcaaaaa aattgtaagg aagagtatga atgtgtgaaa aaggtaggag cttatatgta
    67741 taaggaatac tccagagaat taccaagaca agaggagtta tatttgatga ttcatattca
    67801 taagatttta ggagaattat gcgaaaatag ttagaatatc ttaatatgct agtaatatta
    67861 taaaaaatta aaaattaact gcactttaaa tatgaataat tgcattactt aagggggttg
    67921 tcttaaaatt gattttttta attaaatttg aagctcaact ccttttttaa acctttatat
    67981 cattacaact ttaatgttta tacgcctgta cttcagatgt atatctactt tttacatttc
    68041 tcaacatgca aatctaccat tctgtatata gtaaatgtat tatcatgttt gttttattca
    68101 agcacactta taatacgctt gattttttca caatgatgaa atatactaat gggtgttata
    68161 ggtataagaa tcgcattaca cttgaagaag taagtgataa atgagatata aatcctcata
    68221 tgataaacta ctatttcatt gaggaacata ttctaagtga tgtcaagata ctacaatatg
    68281 actaaattcc tagtgataaa aaagtctacg aatgagtgta gaaaggggaa ctaagatgaa
    68341 taaagtttta attatagatg atgataaaga tctttgtatt ttgttaaaaa agagtatttc
    68401 aattgaacag attgaagcaa actattgcca ttctgggaga gatggactgg ttgaactttc
    68461 aaaacaagat tatcagttag tagttctaga tgtgatgatg ccaggtatgg atggttttga
    68521 aactatggaa caaatacgaa aatatagcag tattcctatc ttaatgctga catcaaaaag
    68581 tgataattac agcaaagtgc atggattgcg agctggtgca gatgactatc taaccaaacc
    68641 atttgaaatt acagaattta ctgctcgtgt actgtcttta atccgacgtt acacccgttt
    68701 taatccaaaa aatgaggagc cacagcaact ttctttcaaa ggtttgttga ttgaccttga
    68761 ccagcataca gttactacca atggcgaacc tatgttgctt ccacccaagg aatttggtgt
    68821 acttctttac tgtgcaaggc atcagggtaa gattttgaca aaacagcaga tttatgaagc
    68881 cgtgtggggt gagccatatg tatatgatga cagcaatatc atggctatta tcagtcgcct
    68941 aagaaaaaaa attgaactag acccatcatc tcccatctat ttgcaaacaa taaaaggaat
    69001 tgggtatcaa ttcaacacgg aggtatgaaa atggatgaac aaacgataat tcttttctta
    69061 ctcttgctgt cgattggtct actttttctt tccatatttg ctttttccaa gcttgggcat
    69121 attcacaaac gcttaaaaga tatagaggag atactcgctg atgtacaaat tggagacgaa
    69181 aatcgtaaaa tactaattaa gccatgtgat gttatggctc cattggttta tcagcttaat
    69241 gagattgtct acgattatga aaataagtta ctttctctga aaaagtcgga taaagctagc
    69301 aaacaactta tgacaagttt atctcatgat gttcgtacac cattaacaac tctgattggt
    69361 tatctggatg ctgtacacag tggtatagtt atcgaacaag agcgggagga ataccttgaa
    69421 atcgctaggc gtagagccta cgacctcaag gattacattg atgttctttt tgactggttt
    69481 cggttgaact ctgatgaatt tacgctgtca atagaatctg tggaaattgc agagttgtca
    69541 cgcaatattt tgaaagactg gattcctata ttccatgaaa agaaactgaa ttttgaaatt
    69601 gatattccag aaaatcgact aatggtaaac ctcgacccag atggatattc ccgtgtggtc
    69661 aataatctgg ttcaaaatgt tcttgctcac agtaaggctc ggcaaatcaa gattaccatg
    69721 agtgaggatt ccagaatggt attactccgt gttgaggatg atggtgttgg gattgccaga
    69781 gaaaatttac cacatatttt tgagcgactg tataagtgtg ataaaggacg ttcagaaaaa
    69841 ggaagtggtc ttggtctatc tattgtcagt caaatggtgg agcgaatggg tggtcaggtt
    69901 tccgtagaaa gtgagattgg aaagtatacc gtatttacag tgagcttacc attaatataa
    69961 aattgttttt cccccatgtg acatgtatac acagggggat tttttgtaag ttataaagtt
    70021 gcaaggttaa tacaaggttg ttgcaaggtt aatgtaagat tgaggtggta tgataacttt
    70081 aataaacaaa ggaggctttt attatttatg aataatttaa ttattgaaac aaaaaatctc
    70141 actaagcaat atggtgctca aaagagcgtt tctaatttga atattcacgt tcagaaaggt
    70201 cgcatttacg gattgctagg aagaaacggt gcgggtaaga cgacaactat gaaaatgtta
    70261 ttgggcctaa caaaaccaac tactggagaa attaaaatat ttggtcagga cattcacaat
    70321 aacgagaaga agcttcttcc tcgaattgga tgtttgattg aatcaccagg gttttatcct
    70381 aatctgacag gaacagaaaa tctcaaaatc tttgcaaggc ttagaggaat accaaaaaaa
    70441 aatgcagtag aatcagcact ggatgtagtc ggtttgccaa acaatgacaa aaagttattt
    70501 tctcaatact ctcttggtat gaaacagagg ttggcgattg ctcttgccat tatgcatgac
    70561 ccacaactgt tgattttgga cgagcctatc aatggacttg atcctattgg tattgcagaa
    70621 gtaagaacgt ttattcgtga tctctgcaca gaacgaggta aaactatttt gatttccagt
    70681 cacattcttt ctgaaattgc cttgttggca gatgacattg gcattattga ccatggtatt
    70741 ttgttggagg aagaaagtct tgcccaatta gaagaaaaaa acagtaaata catacatttt
    70801 gctgtatctg atgcagcaca ggcagcaagg cttctggaaa cccaacttaa cctgaaaaat
    70861 ttcaaagtag cagataatta caatattatg ctatatgata cagatgtttc tgttgcagaa
    70921 ataaatcgtg ctttcattct aaacaacatt gaggtatcag aatctcattt atgcgaagat
    70981 actcttgaag attacttcaa gaaagtaaca gggggtgaag gaattgcttg atataatttc
    71041 atgtgaattt tcaaaactca agcggttaaa atttatactg atttctattt taggtgcttg
    71101 cttatttcca attcccgcaa caattttgat tgcaaaggac aacttgccct ttgagcaatt
    71161 gttcaaatta gttgtcaatt ttggatattt cttgctatta ccaattgtat taagtattgt
    71221 tgctagccaa ctatttttta tagaaagaga taatgatgta ttaaaaaatc ttgcaacagt
    71281 gccagtgcca aaaggaaaac tggctctggc aaaattggct gtgttgctgt ttatatcatt
    71341 gttctactct gttgcagggt taggagctac tatcattgga ggtttcattg ttggaatagt
    71401 agagggggtt gctgtaaaat taggaatgag cattgctttt ggaattatgt tttttgttac
    71461 tgtacttcct gttgtggtac tcattgtata tttcaatcgc agctatattt tttctattat
    71521 actttctttt gtatatgcta ttttcaattt tagtatatcc ttaaatatta tcaattttga
    71581 accaaataac ccactattaa gcgtattacc tgctcctgtt ataatgcgtt ggtggatggc
    71641 attttgggga gatcccactg gcgaatacac ggtacttaga cagccatatt tgctctcaac
    71701 tcctgcttgt gtaggtattt tatgtttgat aaccattata gcagtcctgc tgatttgtat
    71761 gatatacaaa aagcaggaga attaggaggt atctatgctt gatataatta ctacagaatt
    71821 tcaaaaaata aaaagatata atattctatg gattggtgtt gttgctgttc tgttttcagc
    71881 actattggca gtttttcagg ttgtaagttc acacggcagt gaccctctaa cgtatgagag
    71941 ctttgcaaac ggagttatct ggaataattt cagtcttagt tttccatttg ggattacact
    72001 tattggagga tatcttatta accgtgaata tacagaccaa accttaaaaa acatcctaac
    72061 tgttcctatt tcattacgca aattgctagt gggaaaatta attgcggttg gaggaattac
    72121 tgtattgtta agtcttttca gcttcttatg cacatttatt ttggggttgt tattttgcaa
    72181 tatcaatata tctgttatac tcgttgtaaa atccttagtt cagattttgt ctgttaatct
    72241 gtattgttat gttgctgttt tgccgattat tgcttatttt ggtcgtaaac aaaatgcatt
    72301 tctgacgggt gtagggattg catttgtata cggtttttgt ggtgtgtttg ttgctggaag
    72361 aaatctgaca gacttttatc caatcacagc aggtcttggt ctagttggat acaacaatgg
    72421 tgctggtact gtttatcagc cacttatcgg tgctatgact ttgattgtaa ttctaatctt
    72481 gacaactatt ctacttgtat ttacacctaa ttatgataaa gttatgacca tatctaagaa
    72541 aaaagggata aagcataaaa agtattctca taaataacat aaatattgtt tctattattt
    72601 aagttgctag acagtgaaaa gaaaaaatct gtcgtacagt ggctatatgc tcatgtattc
    72661 aagaagctac agttttgatt tttcataact gtagcttctt tttgtattta ttaaatcacg
    72721 actatcataa tacttgcaat aggtatagta acaagagaga gtactgtcat atgtgtttta
    72781 tatattacat taagtatatt ctaaaatata tgttttaaat aatatatttg aaaataggaa
    72841 tatttaaata aaaaaaataa tattatatat agttgacaaa aattggcaaa tgatatacta
    72901 tataaatata gaaatagtaa tcattactat tattaaaaag ggaggaatta attatgaact
    72961 taaaaggaac taaaacagaa aagaatttaa tggcaggatt tgcaggagag tcagaagcaa
    73021 gaaataaata tacatactac gcttcaaaag caagaaaaga aggttataat caaatagctg
    73081 ctatatttga agaaactgct aacaatgaaa aggaacatgc taaattatgg tttaaacttt
    73141 tacatgatgg tatgccttca acagaggaaa atttaaagga tgcagcagca ggtgaaaact
    73201 atgaatggac tgatatgtat gcaaaatttg ctaaagaagc tagagaagaa ggatttgaca
    73261 agatagctta tttatttgaa gctgttggaa aaatagagaa agagcatgaa gaaagatact
    73321 taaagctttt agaaaactta aatgaaggaa aaatatttaa aagagatgaa gaagttgttt
    73381 ggcaatgtca aaactgtggt catgtgtatg taggtactga agcaccagaa aaatgcccag
    73441 tatgtgacca tccaaaagca tattttaata taaaagctga aaattattaa aaattatcat
    73501 tattaaaaag gaatgttaac tatgaaattt tctaaacaac gagaactgat tttaaatgaa
    73561 atattaaata atccggttca tcctactgcg gattacctat atgaaaactt aaaaaaagat
    73621 aatccgaatt taagcttagg aactgtgtat agaaatttag ctcagctaac ggaacatggc
    73681 tttataagaa aggttagtat tccagggtat ccagatagat ttgatggtcg aatagataat
    73741 cactatcata tcatatgtga agtatgtgga gaggtatacg atttagaatc cgaagttctt
    73801 aataatttac aagaattaat atctgaggag acagacataa aaataacatc ttataacata
    73861 agttttaaag ggatttgtaa taattgtaaa aggtgtagcc aagtaggtta gttttcaaat
    73921 tctaaaaata attaatgagg tgagtttatg tgtagtgaac aaaaattttt tatatgtgag
    73981 acttgtggaa accttgtagg aatgatacaa agtggtggtg tacctatttt ctgttgtgga
    74041 aaacctatga aggaacttgt tcctaataca acagatgcag cagttgaaaa acatgtacct
    74101 gtaattgaag tggatggaaa taatgttact gttaaagtaa gtagcacaac tcatccaatg
    74161 actaaagaac atcatatagc atgggtgtat cttatgactg aacaaggtgg tcaacgcaaa
    74221 tgtctagcag tagatggaga acctgtagtt aaatttgctt tgaatgatga tgataaagtg
    74281 atttctgcct atgcttactg taatttacat ggattatgga aggctgaact gtaatattta
    74341 aataaattga gtcaaaaagg aggctataaa tgtattttca tacaaatagc ctcctataaa
    74401 tttatataaa ttcaagtttt aattttgttt aatgtcaata taatataagg agaaaataat
    74461 atgtcaattt ataaatgtag tgtttgtgga tatatttatg atgaatctaa gaatgataaa
    74521 acatgggatg aattaagtga agattgggaa tgccctgtat gtacaaaagg tcgtagttat
    74581 tttggaaaga taagtactgt ttactatgaa gaagatgaaa agatagcaga agacatagtt
    74641 gaagatgaat ctaaattaaa tactgaaaaa gagggagatt taaattactt aagtacatat
    74701 ttaagaagag atgatgaagt tgagaaacat atggatataa ttcacgaaat ggctgttaca
    74761 ggaaaatcta taatagaacc tatgagaact aaactaccag taatttcttg ggatgatatt
    74821 ttaattatgg gtgctcaatt aaatccatta cctttaaatg agcatgatga agtaaataca
    74881 acaacaataa taggaaaaaa agcaaagaaa cctatgatta tagaaaatcc agtttatatt
    74941 tcccacatgt catttggagc tttgtctaaa gaactaaaaa tagctttagc aaagggtgca
    75001 gcccaaaata agacagctat gtgtagtggt gaaggaggta tattaccaga agagaaggaa
    75061 gcttcataca agtatatttt tgagtatgta ccaaataaat atagtgtaac tgaagaaaat
    75121 cttaaaaatt ctgatgctat agagataaaa attggtcaag gaacaaaacc tggtatggga
    75181 ggtcatcttc ctggcgaaaa agtaactgaa gaaatagcaa aagtaagaaa taagcctgta
    75241 ggtcaagatg taataagtcc atcttgtttt gaggaaatac aatccaaaga ggatttaaag
    75301 aaacttgtag atgaacttag agaagtttca gaagggcgtc caataggtgt taaaatttca
    75361 gcaggtcata ttgaaaaaga tatggaattt atagcttatg ctaaacctga ttttgtaact
    75421 attgatggtc gtggtggagc tactggagca agtccaaagt tgcttaaaga tgcaacttca
    75481 attccaacaa tatttgctct ttatcgtgct agaaaataca tagatacaca tggattagat
    75541 atagatttgg ttataacagg tgggcttcgt atatctactg attttgctaa ggcaattgct
    75601 atgggggctg atgcagttgc tattgcaagt tctgctctta tggcagcggc gtgtcaacaa
    75661 tatcgtatat gtggttctgg taagtgtcct gtaggagtag ctactcagga tgaggaattg
    75721 agaaaaagat tacatataga aaatagtgct aatagagtgg caaacttttt aaatgtaagt
    75781 ttagaagaac ttaagacttt tgctagaatt tctggtcata aagatataca tgatttaagt
    75841 gttgatgatt tatatactgt taactctgaa atatcaaatt atacaaacat acagcatgta
    75901 tagattgaag tttgaaacta ttagatttta gacagctata aaagtaaatg ataaatatat
    75961 tttataaaag agagtgtctt aaaatgaact ttttagttca taagtcactc ttttttgtat
    76021 gaagccaaat atatttatca ttttagcaat gaaaaagaat cttatctctt tattttgaga
    76081 tagactcctt ctatttatga aaattaaaga tattaaattg taaaatattc tgtgatgtcg
    76141 tactattaaa ctaaagattc tgtactttaa agtaaataaa aatttaagga gtgattatta
    76201 tggaaagatt gaagatacaa gttttagtcg acaataatac ttatattgat agatactttg
    76261 ttggagaacc agcagtaagc tattatattg agattgatgg aaataggatt ttgtttgact
    76321 cagggtattc agatgtattc atatcaaacg ctgaaaaatt aaatatagat ttaggaaatt
    76381 taactcatgt tgttttttct catgggcata atgaccatac aagaggtatc cagtttttag
    76441 aaaataggta tgatttatct acagttgaac ttatttcaca tcctaactgt tttataccta
    76501 gaaaacatgg agagaaaagc ataggagctc cattttctgc tgaggaaatt aaaaatattt
    76561 ttatgtataa tcctaaggat aagccattta atctaagcaa gaattgtgtg tttttaggtg
    76621 aaataccttc tataaatgat tttgaaaaaa gagctaaaat tggtaaatgt aaaataggag
    76681 atttgtggga agatgattat gttttagatg attctgctat agtttgtaaa actgataaag
    76741 gtatttttat tgttacagga tgttctcata gtggaatttg taatatagta gagtatgcta
    76801 aaaaggtatg tggagatgat agagttattg gtatactagg tggttttcat ctttttgaat
    76861 tgaataatag gttagatagt acaatacaat atttggataa agaagaaata agaatgttgt
    76921 acccttgtca ctgtgtttct tttaaggtaa aagcgaagat gaatgaaata ttgaatataa
    76981 atgaagttgg agtagggctg accataagta tatagtattt gaaagtatat aagatttaag
    77041 ttgaaggtta aaaagatatt ttctatagaa aatatctttt ttgttacgtt tattttaaga
    77101 gaaatcaata tacttttata tgaaatattg taaaaaaatt tatttttaat gagaatatat
    77161 tttcattaat aaacaatttt attatgtatt aataatgtta gaataaatat aaataaatca
    77221 aagttactta cattacagta tattttttca caaaatatat tgatttattc ttttaaagtt
//
LOCUS       DAMJVG010000008        75558 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.008, whole genome shotgun sequence.
ACCESSION   DAMJVG010000008 DAMJVG010000000
VERSION     DAMJVG010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 75558)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 75558)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..75558
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.008"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            46..120
                     /locus_tag="PC512_000632"
     tRNA            46..120
                     /locus_tag="PC512_000632"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:78..80,aa:Thr,seq:tgt)
     gene            complement(280..957)
                     /gene="srtB"
                     /locus_tag="PC512_000633"
     CDS             complement(280..957)
                     /gene="srtB"
                     /locus_tag="PC512_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtB"
                     /protein_id="HDF2440405.1"
                     /translation="MKKLYRIVINIILVLVILYSGFNIYSKLTKYNHDTKISSELQKK
                     EYKKEDLSKINSDFKFWLSVENTNINYPVVQSKDNSYYLDKDFYKKDSISGTLFMDYR
                     NKSIDDKNIIIYGHNMKNKTMFNNLNKFKDADFFKKNNKIKITLNGKEFLYDVFSAYI
                     VESDYDYLKTNFNNESDYQNYINDITSKSLYKSPIKVNSNDKIVTLSTCTYEFDDARM
                     VIHGRLI"
     gene            1089..1423
                     /gene="rnpB"
                     /locus_tag="PC512_000634"
     ncRNA           1089..1423
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="PC512_000634"
                     /product="RNase P RNA component class A"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00010"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00010"
     gene            1701..4244
                     /locus_tag="PC512_000635"
     CDS             1701..4244
                     /locus_tag="PC512_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPOR domain-containing protein"
                     /protein_id="HDF2440406.1"
                     /translation="MKVLSENNIIRNTVLNVTASFLKQESKINEKLDGVLEKKFEKVE
                     FNEAKYAELLKFNILFYKTLARNTEPLIGKWIVDKYIPEIDELEKDLELTTAKCRKYV
                     NKAMKEGLDSLKANDLNSFLAYDKMELSERRRRLEKDYKVLNLYKDLLNISLRKISLE
                     KKECGDLFLKNQADAKRELKREIIFCVNKILASNKDVVPNNVEENNEQNKVEIKATEI
                     EDLQLGKDNSENDMLLNEIKNSKVKHESKSNDIESKFIDKLNSLNNESISQTIHNEYK
                     KLCGLEELHSVEAYGFGKEIIKDFACATVVLEFLKRRNRDLIEGAMRLTIIGEFGPEN
                     FKEFVDYVIKNKTEISEDTWNKAQNLIKDNYSELENHEIASKRTRRNKDIDIEEYIYM
                     IKNADKDICFRSSISIEDDAEEGTKEEVDSNNQDIGDVVEDKDTTDKEYDSNKEDIIE
                     PENKKSKKKAKLFGFIKKDNEEAEQEEENLNDISPDIILDKPVENHQVKSEEIEQNEL
                     KEIKQEEPSQHIEEERSVKIEKPINNNLDEKVSSNNESKLEKESKNLEDKKAKEIKEE
                     KLENEKSVVIPIKKKENSNKKSKNSSKDKYRENKKEMKNYVSDKEDSLDDEEVVSKKS
                     RLKETIIAVVIVVIVGVGYFITVGNNKKNDKENIPKSSTQQQANNKLTEEEKKAQAEK
                     EKKEAEEKAKAEKEAQEKAQAEKKAKEMEAYKDGKGVYYTVYAGSLKVEKTAKETAKE
                     YEAKGISSTIIQENGYYKIKIGDYSQYGEAQEKCNELAKKSIDTYIAMYDKYYDYKLE
                     ELKESAPSLSAEELKQKYEDLRSELKNKSGYREYVKHLDKLYEEIVEGA"
     gene            4367..6358
                     /locus_tag="PC512_000636"
     CDS             4367..6358
                     /locus_tag="PC512_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440407.1"
                     /translation="MLKLGEKIIYELSDGFELSGISRYSKEYKKLHITNLGNIIISKS
                     DEVNEDTGVKYIYSFSDNKEKLEAVLEDSQIIVYGNNLPFYIKSENSSKNVTANLTMK
                     ITLDEYDLICKSQREFIFYLKDNMTILSLDDNKFYMGGINKDNEKFIFISGKNRFEIN
                     FDDIERYILEDKRVSLKGYFHMEREGIIVRSVSIFNNNIDSVVPSDLNERVKDNQKIG
                     NLPKDCEIVFCKISGNIDGFDYKNTNMLLVKYQDQLIFINKKSKKTIVKSAKDNCSKL
                     NLGEDIILYDNKNVFNLHINDKNREIMQIDDLKDIENEIVGYTLKHAPFFIQEDFDSL
                     TILKSFQKEIISIKNSDIKDIVINKELENENSNFVETEIKFNNQKVLLNLSKSMVQKL
                     MQDVFIYAKQPLLKENSIEVIYKNWSKAMNDMIIFNFFGNIYYMKSEFDKILEKELND
                     EIRIEVINSLYKQIQEQRNNLDLLSAYMPRILENQEIDLFEKYNTKLDVQVFKQIKNL
                     LSDLSYNISSYLNEVEKSLDNIIFVISGEDKKKYNYRMLKESESASLDVFLKQAISRL
                     NHLVENMYPYYVDETSREMFKLFELLWKNYRNIDDDSIKEILFERITNTYVFKQLTLN
                     NSTKERRKDIIEKIYNSVDYGTNKLDENMFFTGGIKYVK"
     gene            6348..6668
                     /locus_tag="PC512_000637"
     CDS             6348..6668
                     /locus_tag="PC512_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440408.1"
                     /translation="MSSKYNVWTFNYEFLGLDSGDEKNNEVYYEIDLDEILNENYIDE
                     DIDSGLDSDGNSILGELISEMDIDEDVSVDMTYQELEVDLEDLDSYLDEDIDSDIKGI
                     LDEI"
     gene            6866..7735
                     /gene="galU"
                     /locus_tag="PC512_000638"
     CDS             6866..7735
                     /gene="galU"
                     /locus_tag="PC512_000638"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HDF2440409.1"
                     /translation="MTVKKAIIPAAGLGTRFLPATKSQPKEMLPIVDKPTLQYIIEEA
                     IESGIEEILIITGRNKKSIEDHFDKSVELELELEQKGKTEMLEMVRDISNMVNIHYIR
                     QKEPKGLGHAIYCAKSFIGDEPFAVLLGDDIVDSDVPCLKQLIDTYNEYKTTVLGVQK
                     IAKEDTNKYGILDVKHIEDRVYKVKDMVEKPAIEEAPSDIAILGRYIITPAIFSILEK
                     QTPGKGGEIQLTDALQTLGKQEAIYAYNFEGRRYDVGDKIGFLEATIDFALKRENLKD
                     DLMDYMRKKVSEK"
     gene            7759..8772
                     /gene="galE"
                     /locus_tag="PC512_000639"
     CDS             7759..8772
                     /gene="galE"
                     /locus_tag="PC512_000639"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HDF2440410.1"
                     /translation="MAVLVAGGAGYIGSHTAIELLESGYEVVIVDNLSNSNSIVVDRI
                     KELSKKPVKFYNIDIRNKDEMHVVFKENNIESIIHFAALKAVGESVEKPIEYYSNNLI
                     STLNLFELMREYGVKKFVFSSSATVYGDPHTCPILEDFPLSVTNPYGRTKLMIEQMLV
                     DISKADKSLDIALLRYFNPVGAHKSGRIGEEPNGVPSNLMPYITKIAVGKLKELSVYG
                     NDYPTHDGTGVRDYIHVLDLAAGHVKALQKLEENPGLVVYNLGTGKGYSVLDLVKAFS
                     KASGKEIPYKIVGRRAGDVAMCYADSSKAEKELGWKAKYELEEMCEDSWRWQSMNPNG
                     YEE"
     gene            8884..10818
                     /locus_tag="PC512_000640"
     CDS             8884..10818
                     /locus_tag="PC512_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp22"
                     /protein_id="HDF2440411.1"
                     /translation="MKKSLKKYLVLALTLVLVFACGVPESSAASKHVIIVNSRKNTLG
                     YFVNNKLVKEFRVATGKKGSETPTGKTKVVNKIKNRPYYKGNIPGGSPRNPLGDRWMG
                     LALKGTYGDTYGIHGNNNESSIGKHISGGCIRMHNKDVRWLFDQVPVGSDVIIDYSND
                     SYVKIAAKYKINLNQTGWKTENGKKYYVKSDGTYQKNSWLKVNGKMYYFDASGVMQTG
                     WKTINNKKYYLGTDGARVSGWKVIDGKTYYFNSDGVMQTGWQEKNGKKYYLGSDGLAV
                     TGWQEIDGNKYYFDKTGIMQTGWQQIDGKSYYLDKDGKMLTGSQKIDGKDYTFNEDGT
                     INPTWDTIIGANRFDTAKKISSVGNWNADSSDTVILVNGNAIADGITATPLASSYDST
                     ILLTNTANLPTETVEEMKLLAPKTVILIGGENAISSKLEQEIKTTFNTETKRIAGQDR
                     YQTATRIAEELGNREEIKTAYMVSGNGEADALSVASKAGEEKQPIILVNKDGITEESY
                     KWLTERKLENAYFIGGPSAINDSVIAKMNDITTEDISGNRIYGDSRVDTNAKVIEKFY
                     GDTDLQAVLVSKSDALVDALSAGPLAVKLHSPIVLMDNSGLSSEQQRVFANKKVETPY
                     QIGGGVSYIVMDKLMDILAK"
     gene            10973..11836
                     /locus_tag="PC512_000641"
     CDS             10973..11836
                     /locus_tag="PC512_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3800 domain-containing protein"
                     /protein_id="HDF2440412.1"
                     /translation="MLSSYVKRVSKIIKKKYIMFIDESGRADINHEDPFTLTGVIFEY
                     KYAVSQGDYVCSLRKEMDAFKEYCFGTSNIGIHLTDISRKSRAFEKFDDSQIKLFYDE
                     LPLFLSRLECTIISVTVDKARLKKYYAPSKEPYVVAFIHVLQNFYSFVNNETVESARI
                     VIESRDDVSNLKVQKAFFDVFNNGTIYLDIDEELRDKVKGFIIAKKEDADYREGLEIA
                     DILCNPLSRARRGLIEANPKCMQYGEKNKIFKSVRNKIYTPTSVNDIRNWGFKEVPIV
                     EPVGPWLEKMR"
     gene            complement(12044..12925)
                     /locus_tag="PC512_000642"
     CDS             complement(12044..12925)
                     /locus_tag="PC512_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF2440413.1"
                     /translation="MNLYHLRYFVTLAHLEHYTKAAENLSITQPSLSHAISLLENELG
                     VALFEKEGRNIVLTKYGKIFLKDVEKSLEILDSSVKSLKITGTGEGQIDLAFLRTLGT
                     DFIPDIVHKFLKSNPAKSIDFKFHTGVTTDIIQGLKERKYDIAFCSKLEKEKGIEFIP
                     VAKQDLVLIVPYSHPLAAKDTIDLKETIPYPQIVFNQRSGLRYIIDDMFKKINQQPNI
                     VYEVEEDQVIAGLVAKNFGIAVVPNMNMLSFTKVKVIQIIHPSWERNFYLAFIKDRYL
                     PPAIKNFKNFVIKNAQL"
     gene            13338..14186
                     /locus_tag="PC512_000643"
     CDS             13338..14186
                     /locus_tag="PC512_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HDF2440414.1"
                     /translation="MNNQKNLNIPITISSYTLGTEVSFRDRVRIAKEAGFDGIGLRAE
                     NYIDAKNAGVTDEEMIAILNEYDMKVTEVEYITQWGREEDRTEAQREKEQNVYHMAHL
                     FNVKHINCGLLEMIPEEQIITALGELCDRAGELIIGLEFMPYSGVPDLATAWRVVKGC
                     NRENAMLILDTWHWARAKQTAEDLAPVPADKIVSIQVCDVLETPYEKLRDESLHDRLA
                     PGEGYGNTEEFVKIIKEHNISPRVIGAEVISDSLISKGLSTAAETVFNATKKVLDKAW
                     SEVSPK"
     gene            14250..16172
                     /locus_tag="PC512_000644"
     CDS             14250..16172
                     /locus_tag="PC512_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDF2440415.1"
                     /translation="MKISSMFTPIRIGSMTVPNRFVVPPMGNNFANTDGTLSETSKAY
                     YLERALGGFGLITIESSVVDKKAKGGPRKPCLYDDSTIDSFKNVIDACHDAGSKVSIQ
                     LQHAGSEGNEKVAGHPLKAASAIPASNGRNTPLAITTEEIYELIESYGDAALRAQKAG
                     ADAVEVHCAHGYLVSSFISQRTNKRVDEFGGCFENRMRLPRLIIENIRKKVGNSLAIL
                     CRINSTDDVPGGIDVHDSSVIAAYLEDCGIDGLHVSRSIHIHDEYMWAPTTLHAGFSA
                     ELVTEIKKAVSIPVITVGRYTEPQFAELMVRQGRCDLVAFGRQSLADPEMPNKAKNGK
                     LDEMIPCIACLQGCVPNMFQGKPIACLANPILGHEAELKPAEISKEVLVVGGGVGGML
                     AAWVCAKRGHNVTLVEKSEVLGGQMRLAAYPPGKGDITNLVRSYISKCNQYGVKICTN
                     TEATVELIKEKSPDVVIIATGATPLVLPIPGINDSGLIHAVDLLDGKKSCGKKVLVVG
                     GGMVGCEVAAFLGEQEHEVTVIELREEVGADVISEHRKFLMNDFENYNIHTITGAKVS
                     KFYDDGVDYLLTDGTEHDLKGFDSVVLAMGSRNYDPLSEVIKEVVKETYIVGDAVKAR
                     RALDATKEAFEVALNI"
     gene            16254..17117
                     /gene="aroE"
                     /locus_tag="PC512_000645"
     CDS             16254..17117
                     /gene="aroE"
                     /locus_tag="PC512_000645"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HDF2440416.1"
                     /translation="MEISGRTGLFALIGTPVGHSKSPVMYNYSFKKLDLDYRYLAFDI
                     TVDKVKEALLAIKTFNIKGANVTMPCKSAVTEYMDELSPAARIIGACNTIVNDNGKLV
                     GHITDGVGYVRNLKENGVEVKGKKITIMGAGGAATAIQVQCALDGAREISIFNPKDDF
                     YKRAEQTVENIKKDVPECVVNLYDLEDTNKLYEEIQSSDILTNATLIGMKPYDNETNI
                     KDTSVLRKDLVVTDVVYNPKKTKMIEDAEANGCKAIGGLGMLLYQGAEAFNLYTGLEM
                     PVEEVNELCFK"
     gene            17317..18534
                     /locus_tag="PC512_000646"
     CDS             17317..18534
                     /locus_tag="PC512_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2440417.1"
                     /translation="MNNKKYYPTAIALYFSYFLLGIGISILGQYKPEFSSMWGAKTLS
                     DGTLDVSIVLAVIAALGLGRLISYPFAGPISDKYGRKVSGLIGNFLHAIFFVGIVFSP
                     NFYIAYVFAIIGGAANSFLDTCVTPSCMEIFASLGTIANMFTKFTIALAQFLLPFIIG
                     FVAANSISFKVIFIVTAILIVVDAFLIAVLPFPPANNVIDNKGKTVKSEKMKFTPTSI
                     ALVCIGFTCTSTFVLWLNCNQELGKLYGMADPTKIQSFYSMGVICAVLITSLLIKKYI
                     KPIRILVIYPIIALLMLLVVYFVQTPTICMLGGFVIGYSAAGGVLQLTTSTANEMFPT
                     NKGKITSIVMIASSIANYVILNIAGIITKSGGVNGPKYVVLFNVAITFVGILLALFVN
                     MRYEKEKVYDYDV"
     gene            18770..20635
                     /locus_tag="PC512_000647"
     CDS             18770..20635
                     /locus_tag="PC512_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIRAN domain-containing protein"
                     /protein_id="HDF2440418.1"
                     /translation="MENVFKRLQEFNGYDGYKESFEMNYLCIYESIPLREQVELANNL
                     VDEILNMYKSESNEIYLLEGSNSKSLICYFEIFMKKINTLVKEMIIDEKWLYKLTKEL
                     IYKSKKVEYVKLGLVLSEKYLNVENLREVVDTFSKSGEYVFYLSNTIKKLEFYNTYLF
                     NLSKKATGSIKVFAIVNMENLDSKINSYLIEDGYKDTKYERLLMNYIISIVDLNEYLE
                     KRDLDKEKINNLARLICNYLLSVEFKYIGNKLELVNRFLPTVVNYGTNFESLYSIFLI
                     AINVLKDENIECNKIEFEKEINGILLSEKWKNIYFEALRDASGKTEDIIKMSEIYDVN
                     LSFDDLLPYLNRDIRDFEVYWHISKKGTTSSRLKLLNFFEETFKIDDLIGKMKDIEKD
                     KLTQEYYDDMLFFIVLKGSKSLYPEGKNISLKGIFGNINEVRKESINILKRYREKLSL
                     EELKIVKEAYEKEKNVILKDELRRVLYESNNLKKEFVNIEKIKVDEHGKDIYLTSIAV
                     AGSRFRNREYLEKELEKSKIYYLTREKDNLYDEKAIKIVGETGYVIGYVPRKENYILS
                     NLLDGGKLLYCRVTEYNLYEDCIYANVYLSYKDVIETVENSLKMVLDKSRIKLIN"
     gene            complement(20813..22177)
                     /locus_tag="PC512_000648"
     CDS             complement(20813..22177)
                     /locus_tag="PC512_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2440419.1"
                     /translation="MSQLLIKNAYLITMNADREVYENGSILIENNIIKEVGKFDINIV
                     DKDAEIYDAKGKILMPGLVNTHVHLSQQLGRGLADDVVLLTWLRERIWPYESSFNYED
                     SLISSTACCVELIKSGVTTFLESGGQYVDAMVEAVDKTGLRACLAKSVMDTGDGLPEA
                     WQKTTDEEINTQLDLFHKFNNTSNERIKIWFALRTIFNTTEELLVRTKELADKYNTGI
                     HMHIAEIADEISFVKQNNGVGTVEYLDKLGVLGPNLLAAHTVWLTHKEIDLFRLHDVK
                     VSHDPGSAMKVVLGFASIPEMLEKGIPVSIGTDGAPSNNRMDLMRDMYLTSLIHKGRT
                     LNPTVVPAEEVLEMATINGAKCALLEKEIGSLEVGKKADMIILNPDTIHCLPMHNPIG
                     NIVYSMTSENVDSTICDGKWLMKERKVLVVDESELLNKVKKQASKIKDKAEVKIPSKF
                     KIIK"
     gene            complement(22356..23699)
                     /locus_tag="PC512_000649"
     CDS             complement(22356..23699)
                     /locus_tag="PC512_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HDF2440420.1"
                     /translation="MVPNTNNVQPGGNNSSLSFLDKMFKFSERGSSLKTEVIGGVTTF
                     LTMAYIVFVNPAILSEAGMDKAALITVTILATAIGTLIFAILGNAPFALAPGMGLNAF
                     FTYSLVIGAGIPWQTGLGVVFLSGCVFFTLAVTGLRKTIADAIPRELAVASSAGIGLF
                     LAFVGLKNMGVIIANPDTIVSLADFTPTVLIALFALILMAILEYKKVKGGILISIVVA
                     TIISVIFGFVELPTAIISTPPSIAPVAFKLDIVGALKFSLIGPIFSFMFIDMFDSLAF
                     LITCCKQMGLEDENGEIKDLGRMLYADVSSTLIGSFLGTSTVTTFGESASGIAAGART
                     GLASIVTAALFLATLIFTPLLGIVPTYAAAPALVMVGVFMFESIKQIDFADSKIAVPA
                     FVTVLLMPLTYSISIGLCFGFISYIIMHVVAKETDKISITLWIIGLLAVVNLVLS"
     regulatory      complement(23772..23873)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            24202..24855
                     /locus_tag="PC512_000650"
     CDS             24202..24855
                     /locus_tag="PC512_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HDF2440421.1"
                     /translation="MTKIIKVQKPKFTGELEIIENLEDILEDIFNDEKIFNKIIENEV
                     ISDLDSVRVSFESCIFRNVSFENCNLKKIDLLDVVFENCNLSNTFFDGGSIYRVEFKN
                     SKLIGVRFDDCILKNVLFKDVLGKYSNFSFSKFKIVSILDSNFENSVFQEVKGDNLVF
                     EYTNLKKANFNGTKLSGIDFTTNNIEGIEIGIDDIRGAIFDVSQAIDLTKLMGIIIK"
     gene            24996..26267
                     /gene="brnQ"
                     /locus_tag="PC512_000651"
     CDS             24996..26267
                     /gene="brnQ"
                     /locus_tag="PC512_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HDF2440422.1"
                     /translation="MRDIFIVGFALFSMFFGAGNLMFPPFLGMESGKDWLIPLIGFVV
                     ADAGIAMLVIIATARCKGSMDDVLRRAGKGLARVMSVAALACLALLVIPRTCATTYEM
                     GIMPIFGDHGPVAKAVFSIIFFGLTLAFTIRSSKVIDIIGKYLTPALLLVLFVLIVKG
                     IISPAGPMSPEHMIDKNLFGEGISQGYQTMDALGAASMATIMLMSIIAKGYTSDKDQI
                     GMTIKAGFVACVFLAVVYGGLTYLGATVSTLYDTSIPQASLLVEITSILLYGQVGKVI
                     LGVIVALACLTTSTGLTASISTYFEGISKASYKQLVIGICVASMLISNLGVDSIIAIS
                     VPILQTIYPVLLAIVVMELAGKHIKNDNAFKGAAYVTLVISLLSAINGMTGAVPFIQS
                     LPLAGLGFNWVIPAILGGIVGNFIKSNKQVA"
     gene            26469..27656
                     /locus_tag="PC512_000652"
     CDS             26469..27656
                     /locus_tag="PC512_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3798 domain-containing protein"
                     /protein_id="HDF2440423.1"
                     /translation="MLRKITAFMLSICLIIGLTGCSLLVGKKDKEKIIDDFKVAVVTQ
                     PLSENKVQYNMVEEMAKEYEEENKIDKDKDGQTKVKQTIKHVVLPENFTSNIDSAINK
                     IVKLADDKEVQAIVVSTDQAGLLPALQKVKEKRPEIITISAPMGDDKNQLSQFVDVNL
                     GVSAEERGKVLAERSKEMGAKAFIHYASTDDLKDVNIAKRLEMIKETCKNIGLPFVQV
                     NTPNINTEEDKNKVKQFLNEDIEKQVKKYGKDINVFGVNEYMDEVILTKALELKYIVA
                     EQSNPSPIQTYPSVMGLKISEKDAQNYDKINDMISEKAKAFGMSNRLGGYPMPMDAFL
                     PSVAIYLATEMVKQDLTQEDVCDPDYLEAFTELRFGIGSEFTPLTEVLYNYQSVILSQ
                     LIY"
     gene            complement(27886..29910)
                     /locus_tag="PC512_000653"
     CDS             complement(27886..29910)
                     /locus_tag="PC512_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2440424.1"
                     /translation="MDKKKLILITHDKLNSDHYKEELTNFFGDEIIIETQNILDGIKE
                     NLEGDVVLSLSPLTSNFLIKHFKEDIEIIHGTKALSKLGYEKMMKLPPGTKSLLMTTN
                     KTSAFEMATYLYKIGINHIDFVPTYPDCDEIYDLDTAITPGQIRFIPKYIKNIVDLGW
                     RKISLDTYMSLLVVLKLKNEKFIEKLYKLSKETLSHDFLNTSLDNISKLKTILYMTID
                     EIGDGLIFFNTFNKVTFVNKSLLNMLGLDEKLIKSPSLMEYMPNSFLDKITKNLNIDN
                     MIIYIDEIDKKFILSKKPFYLYKNIEGCLITLKDVNNIEILEQKIRSDSVKRGYVAKY
                     KFNNIIGNSSIIKDCIKKAKKMALTDNPILITGETGTGKEAFTQSIHNHSNRKNKPFV
                     AINCASLPSELLESELFGYEDGSFTGAKKGGKKGLFELAHTGTIFLDEIGDMPHDLQV
                     KLLRVLQEKEIRKIGGTSIIPIDVRILAATNKDLEKLIIENKFRMDLFYRISMFTLDL
                     PPLRKRLEDIPLLLESFLKELPYKNIKLDKSLLEALNSYTWMGNIRELRNCIEYMAYM
                     GSNYLTINDLPQNISSKLNNNHMSSNMSIFNDLNQYDKNICISILKSLHMKPMGRTKL
                     MKFMEYNVTEYEVRNMLEYLTRNGYLISSKGRKGSSITEKGIKIIENNII"
     gene            30300..30968
                     /locus_tag="PC512_000654"
     CDS             30300..30968
                     /locus_tag="PC512_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440425.1"
                     /translation="MSKLESTTEKVEVKWYGYVALILGALFFSGIFKDAPGPLKVLDF
                     NNVLGSFGTLGTINDGVGTLAANFRGDGGTGPRDGWLYALTLIPSVMFALGVVRVIDH
                     LDGMKAAQKLLSPLLKPLLGLPGFAGLTLIASLQSTDAAASMTKELKDDGYIDEKQKA
                     VFCAFQFSGASAITNFFASGAALFPFIGDVPIFIPLALILIMKFVGANLLRLYLNKFD
                     KGEA"
     gene            30970..31455
                     /locus_tag="PC512_000655"
     CDS             30970..31455
                     /locus_tag="PC512_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiG family protein"
                     /protein_id="HDF2440426.1"
                     /translation="MSEVAKKEVKVKKGNVIDAFIGGARNGFQISTNSMAPNVIFGFA
                     IISVFNLTGLLDVIGTIFTPVMSIFGLPGVAATAIMTIFISMGGASGVIAGLFTAGQI
                     SQAHVAILLPMLLLSGAQIQFMGRLLGTAELKTKYYPHMFVIATLNGCIAMLIMNYFV
                     V"
     gene            31516..32637
                     /locus_tag="PC512_000656"
     CDS             31516..32637
                     /locus_tag="PC512_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 peptidase aminoacylase family protein"
                     /protein_id="HDF2440427.1"
                     /translation="METNKDYIEYVHKVYDYLHTIPEKGFEEYKTSEFVLKELEKMGF
                     ENINKGIAGTGIIVTIDSKKEGPVFAIRADMDALEFIIDGEKKMIHACGHDGHTSMLL
                     TAAKLIKERNLVKRGKLKILFQPGEEKLYGALRVIDSGLLDDVEEMVGMHLRPGQDCR
                     LGKAIPAMYHCASCIMEFTIKGITCHGSKPHLGVNAVDAVCLAVNAINAIRVNPAIPN
                     SIKVTNISVKGETYNNIPDEAFMALDIRAESNDIIEELKEKAIHAVKTAVSSINAEAV
                     LISKDGVPAAEFDEELVNLAEETIKDVLGADASIGIFKNSGGEDFHYYTQKLKCKTTY
                     IGLGADATPGFHNPNVTFDTKALEYGVDIWCRLVEKRLG"
     gene            32918..34108
                     /locus_tag="PC512_000657"
     CDS             32918..34108
                     /locus_tag="PC512_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDF2440428.1"
                     /translation="MSKYNFDRVIDRVGTDCVKWDFRTNCSTKAQKDGLPFWIADMDF
                     ECAEPIIEALRKKVEHKIFGYSSNDSDKYFNAVCDWYKRRFNWEINRKDIIFSPGVVP
                     AVAILVRILTNSNEGVIVQKPVYYPFEAKIKSNNRDVVNNPLIYENGTYRMDYDDLEE
                     KAKCSNNKVLILCSPHNPVGRVWREDELKKVVEICKKYDLWIIADEIHSDLIRKGFKH
                     TPLQSLCPEYKDKIVTCIAPSKTFNLAGMQLSNIIVNNDELKKKYQEEVTAVGVATSP
                     NPFAIVATIAAYNESEDWLNELNDYLDNNIQFIDEYLKENLPKVKLVYPEGTYLAWLD
                     FTAYGLNEVELEDLMFKKANVLFDEGYIFGKEGIGFERINVACPQSLLKECMDRLKTI
                     FENL"
     misc_binding    34242..34497
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            34556..35557
                     /locus_tag="PC512_000658"
     CDS             34556..35557
                     /locus_tag="PC512_000658"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HDF2440429.1"
                     /translation="MSTIIPKDYKSSLNVIDTQIAIKKLKDFFEMRLSNELNLIRVSS
                     PLFVLPETGANDNLNGEKAVSFDIPFMNKNAEIVQSLAKWKRLALKKYGFEVGSGLYT
                     DMNAIRKNEELDNIHSLYVDQWDWELVIDKSSRNEKTLKDVVKRLYGVFKDTEIFVCS
                     MYEGIKEILPEEITFITSQELEDMYPELSPKEREDKIVKEKKAVFITQIGKTLISGEK
                     HDGRSPDYDDWELNGDILFYNPVLDSALELSSMGIRVDEESLDRQLKLAGCEERKEFD
                     YHKMLLNGELPYTIGGGIGQSRICMYFLQKAHIGEVQVGVWPQDMIQNCSSAGIELL"
     gene            35661..36050
                     /locus_tag="PC512_000659"
     CDS             35661..36050
                     /locus_tag="PC512_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1232 domain-containing protein"
                     /protein_id="HDF2440430.1"
                     /translation="MEFLKIIINIVLDILKKILVRFKNAKFGLVFVFDLLKLPDFMTD
                     KRINIVDKIKVISVLIFTISYFVSGVDIIPEMIAGAFGFIDDAIVLIWSIGIVNEEIN
                     KYRVIAKKDKHSNIIENVEFSIKDEEE"
     gene            36211..37419
                     /locus_tag="PC512_000660"
     CDS             36211..37419
                     /locus_tag="PC512_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate/amino acid:cation symporter"
                     /protein_id="HDF2440431.1"
                     /translation="MKKKIGLVPKLIIGIIVGILIGSYAPEIIVQILVTVSTLFSAFL
                     KFVIPFIIIGFVTAGIADLATGAGKLLGITTGIAYGSTLIAGLLSFAVSTLIFPNFID
                     ASVASQIGDPEAGMLAPIFTIPLEPMVDVTAAIVFAFVMGLGISALRNHGKGETLFNF
                     FQEFQGIVTKTLSTVIIPLLPLYIAGTFANITIAGEVWTILGVFWKVYLVVIPLHFVY
                     MACQFTAAGVFSGKNPVRMLKNQVPGYLTAIGTQSSAATIPVNVGCAEKNGVSKQIRE
                     FVVPLCATIHLSGSMISITGFTTAVLMMNGMPHGIGVLFPYIAMLGIAMVAAPGAPGG
                     AIMSALPFLPMVGIPSDGGLASLMIALYLTQDSFGTACNVSGDNAIAVVVDKINDGMS
                     KKGNKEEQSA"
     gene            complement(37505..38581)
                     /locus_tag="PC512_000661"
     CDS             complement(37505..38581)
                     /locus_tag="PC512_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003415975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDF2440432.1"
                     /translation="MSTNHGANLYSLSSKYGFSKEEFMDFSSNINPFGTSSLAKQYIV
                     NNIDMVSMYPDPDYIDLKTSISNYCKCSIDNIVLGSGATELISSFIHTINPKQALLLS
                     PAYSEYEKELSKINCSIEKYFAKEEDNFHINLENLIKTINAKDYDLVVICNPSNPTGF
                     AFTKVEVREILKNTDSFLMIDETYVEFTDTDTYSCTQLVDDYSNLFVIRGTSKFFSTP
                     GIRLGYGLISNTNVKNEINKNLDLWNINIIASKMGEIMFSDLDFISNTISLMNTERDY
                     LLKELKNIKSLDIYNTKGNFILCKIKTKELTAKSLREQLLPQKIIIRDCCSFEGLDEY
                     FFRVCILKPNENKLLISSLKAIFK"
     gene            38810..39337
                     /gene="hpt"
                     /locus_tag="PC512_000662"
     CDS             38810..39337
                     /gene="hpt"
                     /locus_tag="PC512_000662"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HDF2440433.1"
                     /translation="MYKVTGKMLTEEQIKEKVYELGKKIEEDFKGEDLLVVGILKGAS
                     VFVSDLIRCIDLDVNIDFMSVTSYGNSTESSGTVKILKDLDVDIEGKNVLIVEDIIDS
                     GLTLSNLVAALKTRNPKSLKLCTLLDKPQRRKANIPVDYVGFVIEDKFIVGYGIDYAE
                     KYRNLPYIGIVEDVE"
     gene            39426..40358
                     /locus_tag="PC512_000663"
     CDS             39426..40358
                     /locus_tag="PC512_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HDF2440434.1"
                     /translation="MDIQLNILLFFQNLRNPILNFIFLVFTISTEAPLLILITTIIYW
                     CINKKCGQKILFAIIGNFVVNLGIKEFVKAPRPIGIKGLESLRVSTAGGYSFPSAHTQ
                     TATTFWVSIMTIFKKRYLHLIGAVMVLGVGLSRLYLAVHWPIDVIAGWILGIFFTVVF
                     VKIFDYIDDNKNYILLVVLLIPFIIVAIFLNSPEYFEKFGIIVGFVFGYMVEDRFVKF
                     NTDNNNKKINFSNKNKGSKNIIFSRICRFLVGIVTIGMLYIGIKLFISMLIVTLNISD
                     STMSIIFMNFIKNTVVVFYGIAGAPALFKLLKLN"
     gene            40420..41646
                     /locus_tag="PC512_000664"
     CDS             40420..41646
                     /locus_tag="PC512_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDF2440435.1"
                     /translation="MKKVVIIGGGPAGMIAASTACEKGYDVTLIEKNHKLGKKLAITG
                     KGRCNITNACEIEELIENVPTNGKFLYSAFYTFTNDDVISMFNNLGVKTKTERGKRVF
                     PESDKAFDIVNALERQLKSKKVNILLNSKVEKIISKNNKIEKVILNDKKEIKCDSVVV
                     ATGGLSYPLTGSTGDGYKFAISQGHTIIDTKPSLIGIEVQESFTKDLEKLSLRNVEIR
                     VFNSKQKKVYSDFGELEFTKFGLDGPIIKSASCRMKDTRKENYTILLDLKPALDEEKL
                     DKRVQKDFQKYTNKKFEKALDDLLPKKLIPIIINLSEINPNTVVHQISREQRKNLVHL
                     LKNLKFTVKRYRPIEEAIITSGGVKVNEINSSTMESKLVEGLFFAGEVIDIDAYTGGF
                     NLQIAFSTGYLAGFNC"
     gene            41730..41951
                     /locus_tag="PC512_000665"
     CDS             41730..41951
                     /locus_tag="PC512_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000002841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta-type small acid-soluble spore
                     protein"
                     /protein_id="HDF2440436.1"
                     /translation="MASNNNNNRTVVPGAKEALNQMKLEIANELGMSNYQQVDKGNLT
                     ARENGYVGGYMTKKLVEMAEQQMAGKSNR"
     gene            42140..42310
                     /locus_tag="PC512_000666"
     CDS             42140..42310
                     /locus_tag="PC512_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440437.1"
                     /translation="MSSVNFEDLKNKFINSDLDEKIRIYTTTEGLSVEQFKELLKYYP
                     IQHLSKLEKALG"
     gene            complement(42403..42864)
                     /locus_tag="PC512_000667"
     CDS             complement(42403..42864)
                     /locus_tag="PC512_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440438.1"
                     /translation="MQIEQLDLETRNKIYCYTKKILRKYQKGITSGKLTADKFADNIL
                     SQDFISSILNEKIVNETNFKISYRNYIETLINIQNENLSNLRKKSTKTAKCFNISQIT
                     QLKNLLSNTGYNLLIPYKYLTARDIEGIVTLINTGSIELGNERIYNYISKA"
     gene            43047..43514
                     /locus_tag="PC512_000668"
     CDS             43047..43514
                     /locus_tag="PC512_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440439.1"
                     /translation="MKMLNGIIKLFYSEIVKTKINNLDSSGYSLRDECKEIRNITLKI
                     DSVFFKLLKLAFGSILLMVAFNLNMVLGIGVFLVGVVYILYKRNMEEQVKEHINNVKN
                     NIDISKITFMDEKGRTGLNALITLLLIGLLTGFNWILVASFVVVFVFTIKNVC"
     gene            43557..45320
                     /locus_tag="PC512_000669"
     CDS             43557..45320
                     /locus_tag="PC512_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="HDF2440440.1"
                     /translation="MTNGSYKMKNLVEISAMVTESTDFFNIKDDIIEKMLEVVHPTKA
                     CVNLFYKNDSKYAYLVCSQTLEYVPQIFPINSLKGAKIDFDTYPEYIHEAVNEKKIIY
                     VENVFEDSRAEGERDLAKAEGYIGRIVFPFIINNVVVGFMTCFLKEDDYITEQDIDFI
                     SSVASLLSLSIEITNKNNNVQILIDKLRGSISAINEATKKLYLNKSIDGFLENLSKQA
                     CNITNSKEALIIINSHHNKDAIVSCYNVEQKKKTNLYPMIDMFLKKESLGGYLNNLKP
                     CSKKGINLESYIYYKLQDKNETIGCIVCANSKNYTSDDLNILSILSKQVSVGMQLYEH
                     NEKEVKHKVLENELNILNKQQQLIMDKGKMDCNDEKELYFYHKPARVVGGDFYYATKV
                     DDEHIVYIVADVMGHGMVSNYVVAMIKGAFKVLCNQYNTPREIMTNLNRMLYDEFDKM
                     GVFTTCLIGIIDTKENMITVSNAGHYSPVVVKKDGTIENNLNCKKGIPIGIMEDATYE
                     NNTLSMEDYAMVCMYTDGILEIKNSSKEEYGINRLENFLKENFRLNQQLIVENLKLDL
                     KNFSSKDNYDDDILIVMLKDR"
     gene            45328..45936
                     /locus_tag="PC512_000670"
     CDS             45328..45936
                     /locus_tag="PC512_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF2440441.1"
                     /translation="MDSNDKKGLKSPEIIIINGSPRINKNCSFIANEVKAMLEECGLS
                     CKIFNIYNMDIEYCTACGFCEKTGYCKFNDDMKPLYKMFDDSKGTIVISPVHFDSISA
                     KLKTVVDRTQAIYASKYVLNKPSIDRSKKRIGMYIAVGGSKSYDSQFKGGQIVMDFFF
                     KSINTKLLHNIYLNNTDDVSYIDNQEFKDIIYKNLKIYIDSI"
     gene            46008..46577
                     /locus_tag="PC512_000671"
     CDS             46008..46577
                     /locus_tag="PC512_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate propanoyltransferase"
                     /protein_id="HDF2440442.1"
                     /translation="MKLPIALSNKHVHLSQADIDVLFGAGHELTKFKPLSQPGQYACE
                     EKVDLVGPKGTLKGVRVLGPARAHTQVEISLADGFPLGVKAPIKESGDIAGTPGVKLV
                     GPAGEVEMKEGVIVASRHIHMSNEDAAKFGVTDKQIVKVKTSGPRALVFENVLVRASD
                     SFNLEMHVDMEEGNAAGVKNGDLVELIVD"
     gene            47095..50634
                     /gene="nifJ"
                     /locus_tag="PC512_000672"
     CDS             47095..50634
                     /gene="nifJ"
                     /locus_tag="PC512_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HDF2440443.1"
                     /translation="MAKFMKTLDGNTAAAHVAYAFTDVAAIYPITPSSTMAEVVDEWA
                     SQGRKNIFGQTVNVVEMQSEAGASGTFHGSLQGGALTSTFTASQGLLLMIPNMYKVAG
                     ELLPGVFHVSARALASQALSIFGDHQDVMAARQTGCVLLASGSVQEVADIAPVAHLAA
                     IEGRLPFIHFFDGFRTSHEIQKVELLENEDYASLLNFEAVQAFRDNALSPNHPVARGT
                     AQNPDIYFQTREASNKYYQNIVGIVEKYMEKMSNLTGRKHSLFDYYGAEDAKYVLIAM
                     GSVTETIEETIDYLNAKGEKYGLVKVHLYRPFSMKHFLDAMPSTVERICVLDRTKEPG
                     STGEPLYLDVRDVFYGKENAPMIIGGRYGLGSKDTTPSDIKTVFDNLVSEQPKNGFTV
                     GIVDDVTNTSLTPSEPIKIASKGTIRCKFWGLGSDGTVGANKQAIKIIGDHTEKYAQA
                     YFDYDSKKSGGITMSHLRFGDTPIRATYLIDEADYIACHKQSYVYQYDLLKGLKKGGT
                     FVLNTIWDQAGLEEHLPAHMKQYIAKNDIKFYTVNAVKLGQEIGLGNRINMIMQSAFF
                     KLAEIIPEEDAVKYLKDSIVKAYGKKGEKIVNMNYAAVDAGINALVKVEVPASWENAV
                     DADKGEVKEPEFIKNILRPMTAQEGNNLPVSTFNGIEDGTFPCGTAAYEKRGIAVDVP
                     EWIIDNCIQCNQCSFICPHSCIRPVLVTEEELANAPEGFEAKKALGKGLEGLKYRMQL
                     SPLDCTGCGNCADICPAKEKALVMKPIDTQLDTELDNWAFAVNPDEVAPKGDVMPANT
                     VKGSQFRQPLMEFSGACAGCGETAYIKVVTQLYGDRMMIANATGCSSIWGASAPSIPY
                     TCNHEGKGPSWANSLFEDNAEYGFGMYTAVKQIRNKIVDAMTELVSMDICEDAKAVFT
                     EWLDSRNDGEASKVASAKVVELLEKPACDCTDEKAKELVKAIKDRKDYLVKRSQWILG
                     GDGWAYDIGYGGLDHVLASGEDVNVLVFDTEVYSNTGGQASKATPAAAMAKFAASGKK
                     SRKKDLGMMAMTYGNVYVAQVAMGADKNQFIKAVIEAEKHDGPSLIIAYAPCINHGLK
                     EGMGRTVANEAQAVACGYWHLYRFNPEVKAEGKNPFTLDSKEPTASFKDFILAQVRYS
                     AIAKQFPEEADGLFAKAEADAKERYEGYKKLAE"
     gene            complement(51026..51922)
                     /locus_tag="PC512_000673"
     CDS             complement(51026..51922)
                     /locus_tag="PC512_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein"
                     /protein_id="HDF2440444.1"
                     /translation="MMRRNIPTKLKTILALGVLTLATASSAVTASASSLENNVNISNK
                     SLVYSNTKYKFSAKPNCSVKPELKPDKDNSCKDKNHNDKNCNNTNKPEDNNNSDSTNK
                     PGNNKPESNKPEDNNNSGSTNKPDNNKPESNKPEDNNNSGSTDKPEDNNNSDSTNKPD
                     DNNNSGSTSESFSAYQKEVVDLVNIERAKAGLNPLTLDSSISNVATKKSQDMIDNNYF
                     SHNSPTYGSPFDMLKKFGISYKTAGENIAMGQKTPKEVVNAWMNSEGHRKNIMNPNFS
                     KIGVGVAQKSGGSIYWTQIFVG"
     gene            complement(52418..53752)
                     /locus_tag="PC512_000674"
     CDS             complement(52418..53752)
                     /locus_tag="PC512_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HDF2440445.1"
                     /translation="MSIIAPIGIIIGIIAIIYFSVKEIHITIAAPIATLIVVILNKMD
                     VVTSMLGADKNNYMGALGNYIMSYFAIFLLGSILAKFMEESGATVSIADFILNKFGSN
                     HPYRVLVAIFIVSFILTYGGISLFVVMFAVIPLARTLFKKLDISWNLIQIPLWLGIAT
                     ITMTIIPGTPAIQNVIPIQYLNTSLTAATIPSIVGSIGCATFGLVYMKYALNKSIRKG
                     ETYATYTSELEEESLDRELPGFFASIFPLLALVIIAITGSTFGSEFMKKNVIYIALIV
                     AILLSAFLFHKFLSSKIQTLSIGASGSIGPIFATSSAVAFGAVIMAAPGFDVFSKLIM
                     SIPGSPLISLTVLTSTMSAITGSSSGALGIVMPNFADYYLSTGLNPELIHRVATIASN
                     ILTIVPQSGVFLTFLSLSKLTHKTGFKETFIVVAVGSLIAEIIVITLGLLMY"
     gene            complement(53814..54590)
                     /locus_tag="PC512_000675"
     CDS             complement(53814..54590)
                     /locus_tag="PC512_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyrate dehydrogenase"
                     /protein_id="HDF2440446.1"
                     /translation="MVKDKVVFVTGAASGIGKQIAESFLKNGAKVMFSDINQEALNNT
                     ITELQKKGYDCMSVKCDVTKEEEINHAIDKTVEKYGRLDILINNAGLQHVSMIEDFPT
                     DKFEFMIKIMLTAPFIATKKAFPIMKKQGFGRIINMASINGVIGFAGKAAYNSAKHGL
                     IGLTKVAALEAADSGITVNALCPGYVDTPLVRGQFNDLSKTRNIPLENVLEEVLYPLV
                     PQKRLLDVQEIADYAMFLASDNAKGITGQACLLDGGYTAQ"
     gene            complement(54695..55360)
                     /locus_tag="PC512_000676"
     CDS             complement(54695..55360)
                     /locus_tag="PC512_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HDF2440447.1"
                     /translation="MDKLEMQEYIANRVSKELKDGAVVNLGIGLPTKVANYIPDNVNV
                     ILQSENGFLGLGSAEDGNSSDETIVNAGGQPVTILPGGCFFDSATSFGIIRGGHVDIT
                     VLGALQVDKYGNIANYMIPGKMVPGMGGAMDLVTGAKKVIVAMEHTSKGSAKILNNCT
                     LPLTATNAVDLIVTEMGVMEVTSDGILLKEINPAFTLDDVISATEAPLILSDSLNGKI
                     SVV"
     gene            complement(55360..56016)
                     /locus_tag="PC512_000677"
     CDS             complement(55360..56016)
                     /locus_tag="PC512_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HDF2440448.1"
                     /translation="MNKIVSIDEALSHVKDGDTIMVGGFMANGSPENLIDYLCSKNIK
                     DLTLICNDTGFIDKGVGKMVVNKQFKKIIASHVGLNKETGRQMNNNETDVELVPQGTL
                     AEQIRAAGYGLGGILTPTGIGTLVEEGKQKIVVDSKEYLLEKPIYADVALLFASKVDK
                     AGNLVYKGSMNNFNNLMASAAKITIVEADEIVEIGDIDPNEVNTPGIFVNYIIEGGNL
                     "
     gene            complement(56025..57203)
                     /locus_tag="PC512_000678"
     CDS             complement(56025..57203)
                     /locus_tag="PC512_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HDF2440449.1"
                     /translation="MKDVVIVSAVRTPIGSFGGVFKNTSAVQLGTITVKEAISRVGLN
                     LSEIDEVIIGNVLQTGLGQNVARQIAINAGIPNSVPSYTVNKLCGSGLKSVQLAAQSI
                     TSGENDVVIAGGTENMSQAPYIVPTARFGSKMGDITMVDSMLTDGLIDAFNQYHMGIT
                     AENIATKFEFTREMQDKLALESQSKAENAIKNNRFKEEIVPVDVLIRRGKIETIDKDE
                     YPKLGMTFEGLAKLKPAFKKDGTVTAGNASGINDGAAMLILMSQQKADELGIRPLAKI
                     KSYASAGVEPEVMGTGPIPATRKALKKAGLSINDIDLIEANEAFAAQALAVKNELQID
                     SSKLNVNGGAIALGHPIGASGARILVTLIYEMQKRKVETGLATLCIGGGQGISMVVSR
                     "
     gene            57558..58460
                     /locus_tag="PC512_000679"
     CDS             57558..58460
                     /locus_tag="PC512_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF2440450.1"
                     /translation="MDIKQLKYFVEIVKSGFNLSIASKTLHISQPALSQIIKNFEESE
                     DVYLFERYKGRLNGLTPAGERFYVNAEHIINEYKNMMEDLREDSVQFKGKVRIGIPPL
                     ILGIAFSDVVAQLVANNPDIEFDIVEKGAYDLNRMLILQELDYAVLLHPHKIDKSVVT
                     EHVLQEDELTAFLNINHPLAKKDKIDWNDLNEQLLAIFNPTFMIHHKLMQKFTDENVK
                     LKRYIMSGSWDFLLLSTTNSDFITILPSPVHDFFENSKIIEKPFNHPITWKVILCRPK
                     KERYSHVDQHVFKFIIDFFSKKNS"
     gene            complement(58676..59488)
                     /locus_tag="PC512_000680"
     CDS             complement(58676..59488)
                     /locus_tag="PC512_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2440451.1"
                     /translation="MFTSILKKLKKDKSFAFACITLSIIIILIIASFILNIDSNAIDT
                     TSKLQEPSLKHIFGTDELGRDYFSRALYGGRISLSVGILSMLISVVFGTAVGVISGYI
                     GGKLDQFLMRLIDMLMSIPSFLVLIVLNTYLTPKVSTIILIIGFLSWMEVSRIVRGET
                     LKIKENEYCLAAKATGIKTRNILLRHIVLNLKETIVVAGSLNIANAILTESALSFLGL
                     GIQLPLASWGNMLQDAQRHIFDKLYLAVFPGLLIFLTVMSLTIISKKFSSNT"
     gene            complement(59491..60450)
                     /locus_tag="PC512_000681"
     CDS             complement(59491..60450)
                     /locus_tag="PC512_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2440452.1"
                     /translation="MLKLILNRVKVLIPMLILISILSFGLLELAPGDPADAYINPLMS
                     SQDIENIRVNMGLDKPVYIRYLNWLKNTLSGNLGISYINHMPVTEQIMEKMGNTFILM
                     GTSLIFSILVAIPLGIFLAVNKNSITSKVSSVFNYIGVSIPSFWIGMILISIFSVKLN
                     IFPSGGMHTIGNDSIGDLVKHLVLPVITLGLYNTAIFTNYVEASVNEQLKKQYVITAR
                     AKGLSEKVILFKHVLKNSLTSLVTILGMSIQKLVTGAFVTEVVFSWPGMGRLMIDSIF
                     SRDYTVIMAITMLSALFLILGNLVADILYLLIDPKIKSSKGGF"
     gene            complement(60556..62115)
                     /locus_tag="PC512_000682"
     CDS             complement(60556..62115)
                     /locus_tag="PC512_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2440453.1"
                     /translation="MKFKKLASLILVSSLMLTFTACASNDKDKSSGSKSGGTVVIPMA
                     SDPDIINGAFANVKEDSLASNIVYAPLYTYEKGNLVNYLAEKVDFKDSKELTIKLKSN
                     LKWHDGKPITAEDVLFTFNTVLDEKQNSPSRQYLLVGEKPVKVEKIDDLTVKITLPTA
                     SESFLYGISKISPIPKHVFEGESNIAKSEKNNNPVGSGAFKFKEWKKGESIVFEKNAD
                     YFGGEPKADSIALKIIPNEASQEAALNNGEISLMKTSAEGYEKAKSNSNLQTYTYSEE
                     RLNYIVFNQNISNMANKEVRQALSYALNRNEMIESAYGKEGSVPAKSILVPEADFYTE
                     EGVEGYDQDTNKAKDLLDKSGVKIDKLKIGYNTGRFGHKNYALVAQQELKKIGIEAEI
                     VPYESKAFFNILFSNSTECDMYVNGYAWGLEPNPYRGMFETGQYCNQTKYSNAEIDAL
                     WEKGFTELNKEKREEIYKQIQQDISKDAPIYTIDYEQNLMAAQKNLKGIKDAKPSPAI
                     LFEDWSKLYVE"
     gene            62334..63311
                     /locus_tag="PC512_000683"
     CDS             62334..63311
                     /locus_tag="PC512_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2440454.1"
                     /translation="MSKALIEVKDLKVYFHTDKGIVKSVNEVSFNINEGETIGIVGES
                     GCGKSVTAMSLMKLLPTSKIEGGEIIFRGKDILKMNEDELMGIRGNEISMIFQEPMTS
                     LNPAFTVGSQIIEGIMIHQDLSKEEAKKKVIDMIKLVEIPRAEEIYNSYPHELSGGMR
                     QRIMIAMALSCNPKLLIADEPTTALDVTIQAQILDIMKNIKEKLNTSIMMITHDLGVV
                     AEMCDKVLVMYAGKIIEVAEVVELFKNPKHPYTIGLLKSKPALGKNKDKRLYSIPGQV
                     PNPIGMPDSCYFSDRCEKVCDKCRTQIPPLIELNSGHSIACWLYKKEEI"
     gene            63312..64283
                     /locus_tag="PC512_000684"
     CDS             63312..64283
                     /locus_tag="PC512_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter ATP-binding protein"
                     /protein_id="HDF2440455.1"
                     /translation="MKKEESLLKVEGLKKYFEVKSGLFDKKIKSVKAVDGISFDLKKG
                     ETLAIVGESGCGKSTAGRTILRLIEKTEGKVEFNGVDIYKLEKEELRKLRPKMQMIFQ
                     DPYSSLNPRLNVEQIISEAVIEHNLVPKNEIKDNILNVVESCGLSKYHLNRKPGEFSG
                     GQRQRIGIARALALNPEFIVCDEPVSALDVSIQSQIINLLMDLQDKYKLSYLFISHDL
                     SVVNHIAHRVCVMYLGSIIEIATKGELYLHSQHPYTKALMSAVPIQDPTIKKNRIILK
                     GDIPSPTNPPSGCKFHTRCPYCKEICKKEIPVLKEISRNHFVACHLV"
     gene            64435..66477
                     /locus_tag="PC512_000685"
     CDS             64435..66477
                     /locus_tag="PC512_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HDF2440456.1"
                     /translation="MSILVTLLGLLVCTTISTVFSKKWSNIPLAIYQIVLGIILSILP
                     FKFSFSFNPEIFVICIIAPLLFSEGQNVSRKELLELRKPILLLAFGLVLITVFAGGIF
                     IHFLIPGMPLSVSFALAAVISPTDLVAVKSITQGLNFPKNIMSILEGESLLNDAAGVV
                     AFKVAVLATVTGVFSIEEAGIQFMITAFGGIIVGSILGYIIIKIRLSLHKWNLEEIPM
                     VIVIQIMTPLFVYFVAEEIGVSGILAVVMAGIAHGIEKEHLQNTTTKLRIISDNTWYV
                     LEYVLNGFVFTLLGFLLPSIYTGLSSKNENMALELTFISTLIVLILFVIRFIWVYLWH
                     NSFIKPKKNPLNNFFVGFLGFKDEEVIKESISKCKYSLIVATCGVHGTFTLATALSIP
                     FYLADKDVFPMRDTVLFISSEVILISLVLATILLPRLLKNNVQESEPLLSDKEAYKLI
                     LKEAILKLSNEKAQEVQPVIHDLNEQLVDSEKGILNTPDNKLISMMIAEADQQGLLAV
                     LKLLEDGKISDRAFKLYRFYITKSRKSVQKSIFKIVKLKISMWIINRKVKKEVKEKIT
                     KIVSENKEIIKEFHHAYALSTKTAISFINKNTDEDNRHEALIAIRFYNRYLNWITRKI
                     QNDDKFEARVEYYRVMAIQSQRDSVQQLVETKQISREVAKELLENILYDEMMMIES"
     gene            66738..67580
                     /locus_tag="PC512_000686"
     CDS             66738..67580
                     /locus_tag="PC512_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF2440457.1"
                     /translation="MIIQQIYNNNVVLVLDENIKKELILTGCGIGFQKKKGQEIDKSK
                     IERTFVIQDESFLDKISKLASQVDEKFFEVSTEIIAYAEENLNTKLYEYIYVALTDHI
                     AFAIKRYHENITIKNDLLHEIKRIHKKEYEIGKWAVDYINKEFDVKFPVDEAGFIAMH
                     IVNSNYKGSSKESLLITKIVKDILNIIRYYYRVEFKEDDINYDRLLTHLKFFAKRLVK
                     KEKINDTNNEIIDIIKVKYEKDYDCAYKIKTHVEKNYDYYVSQDELLYLTLHIKRVIS
                     VLNL"
     gene            67883..69955
                     /locus_tag="PC512_000687"
     CDS             67883..69955
                     /locus_tag="PC512_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDF2440458.1"
                     /translation="MKKVFGVLQKVGKSLMLPVALLPAAGILLGVSNALAGDALLAHF
                     PALANPTFQLIISIMESSGQIIFNNLPLIFAVGVAVGLTEGEGVAALAAIVGFLILNT
                     SMGVMAGVTEDMVDNSMYANIVGIPTIQTGVFGGIIIGIVAAYLYKKFYKIELPQYLG
                     FFAGKRFVPIVTSLVAIAIGIILSFIWPPIQEGLLSFSKNVIEANQTLAAFMEGSLER
                     LLIPFGLHHVFHNPFWYQFGEYVNKAGELVMGDQKIFFAQLKDGVNFTAGTFMTGAFP
                     FMMFGLPAAALAMVHEAKPEKKKFVAGIMASAALTSFLTGITEPIEFAFLFVAPVLFA
                     IHCLFSGLSYAIMQLLGVKIGFTFSGGLIDFLLFGVLPNRTPWYLAILVGIGFAVLYY
                     SVFRFMIRKFNLKTPGREDESETNAEVIEMSKNELASEILIALGNKDNLKSLDACITR
                     LRLVVNDINKVDKEKLKSLGAAGVMVIGNNVQAIFGPKSDSIKSDIKDIIEGKTKVES
                     TVTKNVDKNKVKKNMEVANMENALVEKIDSLTNGEILDIEEVPDSVFSSKLMGDGFAI
                     KSSDGLIYSPVDGTIGVIFPTKHAIIIKSQKSGVEILIHLGIETVNLEGNGFEVFVNV
                     GDEVKAGEKLVKMDLEYIEKNGLSTISPVVFTNLEQNQKLSIKKGVSTAKEENRVSIL
                     RDDIEKIG"
     gene            complement(70168..71037)
                     /locus_tag="PC512_000688"
     CDS             complement(70168..71037)
                     /locus_tag="PC512_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2440459.1"
                     /translation="MDNKIGYLNDNFKIFNIRDKKDIQFEYHNHDFNKIIIFINGNVT
                     YFVDGIPYKLKPWDILFISNNEIHKPVIDSNVFYERIAIWISPEFMKKNSDASSDLEK
                     CFKIATENKCNRLRLNIHDIESIKSFIEQINISESNTEFGNEILRNALFIQLMIFLNR
                     IFLKNENMESTEDVFYDETIKKVLNYINSNIDDKLSIDSISSEFFISKYYLMRKFKSH
                     TGTSIHNYIVQKRLILAKSLITNGHLMSEVCNKCGFNDYSSFVRAFKKNYGVSPKNYI
                     NNKNPLDITLLDE"
     gene            71201..72655
                     /locus_tag="PC512_000689"
     CDS             71201..72655
                     /locus_tag="PC512_000689"
                     /EC_number="6.3.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HDF2440460.1"
                     /translation="MKLNDIIQGLDIINIKGELNIDINNVQYDSRKVTKGTLFICIKG
                     FVSDGHKYIKDAIEKGASAFLVEEDVEIKGCTFIKVKDTRKDMAKVADNFYNHPSQKF
                     NVIGVTGTNGKTSITTILNEILTLNKNKVGLIGTIKIFDGEKDIVSNSTTPESIDLQY
                     HFNNMLDNGCDYCAMEVSSHSLALNRVDETDFKLGIFTNLTPDHLDFHKDLEDYRKAK
                     EKLFFKTTMANIINIDDEGGKKIYENIKGINVPCYTYGVDTKADFMARDIKSDSDGVS
                     YRLITPSYEEVIFIPVPGMFTVYNTLAVIAACYVLGIPKPIYKEGLRLSNGVSGRFET
                     VPNDKGISVIVDYAHTPDALENVLKTTQQFAEGKIISVFGCGGDRDTEKRPLMGAIGQ
                     KYSDLCIITSDNPRTEEPEAIIKDILEGIDKKKENYHVVVDREQAIAEAISMAKKDDV
                     VIITGKGHETYQIIGKVKHHFDDKEVANECLSKM"
     gene            72926..75205
                     /locus_tag="PC512_000690"
     CDS             72926..75205
                     /locus_tag="PC512_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF2440461.1"
                     /translation="MLSDAKNNRYGLSIIAVISILVITISCLIYGSRLNKTLGEETNQ
                     YLSEIANQSVNVLKKQINGDIKLLESISIFIEGEESFEVDNILSILKRQAINSSFKRM
                     GVILPNGTAYTTDGYIEDFSKRDYFLKSMQGEVVITGKLKDVIEDDKNTNSNINVYSV
                     PIYKDNEVKGVIFATHSTKLYEKILSVPTFNGKGYSYITRSNGDIVLNPSSKNANSTK
                     ENLFSYIGRSDSISKSSINNMKSNIKNFKSGSLSYSMFGKGYYLSYAPIGINDWYLFS
                     EVPKTAISEKSYAIIKLTLSACVVLIIIFTALTIYILFIHKKSKEKLEEFAFKDNVTG
                     IGNSNKFNLEGGKFLSSHEKKNLVLIYFDIDKFKLVNDRFGYEEGDRVLKEIAEIIKN
                     IFKEQSVFSRISNDNFAIIFEKKNNRESIIEICELIRKKLSMIKTSLGVELNLIPSIG
                     VYFVEEGETNISTCLDKAMIAKTTVKRKYLKVYEIYAENLKETLIEERDIEQEMHDAL
                     KNEQFKVYLQPKVDLSTTKIVGAEALVRWQHPKKGLISPGVFIPIFEKNGFITELDMF
                     VFTQVCKNFKRWENENFPTFPISINLSRVHLENPGFISELERITKEYEIEPNLIEIEL
                     TESAIFDNTKILFKIMQTLKSVGFKISMDDFGSGYSSLNMLKDMPIDVLKLDRQFFIT
                     VGNAKKSQIVVSSIVQMAKQLDIKVVSEGVETVEQAEFLRFIGCDMAQGFLFARPMPI
                     EEYEKLILDRYSLNRKETN"
BASE COUNT        28723 a         8866 c        12594 g        25375 t
ORIGIN      
        1 taacttttaa aaattagttt tgctaattta caataaaata ggtgtgctgg tgtggctcaa
       61 cggtagagca gctgacttgt aatcagcagg ttgtaggttc gattcctatc accagctcca
      121 gtaaagacta tgtttttagc atagtctttt tttattgttt tttattgttt gatgtatttg
      181 ttattttgta ttaaatactt ttagtggtct aatttacaaa ttataggtat aaaagatgac
      241 acagtttaaa attattgttt taaactgtgt ctgtgagttt taaatcaatc taccatgaat
      301 caccattctg gcatcatcaa attcataggt acatgtagaa agtgtaacta ttttatcatt
      361 gctatttacc ttaataggag atttatacaa tgatttagaa gtaatatcat ttatgtaatt
      421 ttgataatca gattcattgt taaaatttgt ttttagataa tcataatcag attctacaat
      481 ataagcagaa aaaacatcat ataaaaattc ttttccattc aaggttattt ttattttatt
      541 atttttttta aagaagtcag catctttaaa cttatttagg ttgttgaaca tagttttatt
      601 tttcatatta tgtccatata ttatgatatt tttgtcatca atagatttat ttctataatc
      661 cataaacagt gtaccagaaa tagaatcttt tttataaaaa tctttgtcaa gatagtaaga
      721 attatcttta gattgtacaa ctggataatt tatatttgta ttctcaacag aaagccaaaa
      781 tttaaaatca ctgttaatct ttgataaatc ctctttttta tattcttttt tttgaagttc
      841 tgaggatatt ttagtatcat gattgtattt ggtaagtttt gagtatatat taaatccact
      901 gtaaagtatt actaatacta gtataatgtt aattactatt ctatataatt ttttcaatag
      961 atcacctcga gttaaatgta gtttatatat ctatattaca ctatttttga ataaatttaa
     1021 atttttagta taatattact ttgacatgta aaagaatttg tgttaacata actaagtaaa
     1081 ataaatatta agtaagccag ataatcgcat gtaatcttac atgaggaaag tcggagctcc
     1141 atagagcagg gtgctaggta acgcctagtg ggagcgatcc taaggatagt gcaacagaaa
     1201 taaaccgcca ctattgtggt aaggatggaa aggcgaggta agagctcacc agcagctagg
     1261 cgactagttg gctatgtaaa ccccacctgg agcaagacca agataggaat aaagagtgct
     1321 gctcgtactc tccggtaggt aggtcgcttg agcctattgg tgacaatagg cctagaaaga
     1381 tgattatcta atacagaact ccgcttatag acttgcttaa ttatttcgat agtcaaaaac
     1441 atcagtttaa actgatgttt ttttatttgt aaatttgtct aatctacttt taaaattttg
     1501 aggaatattg taatataagt tagtacagat attaaaaatg gtataatata agatagatat
     1561 aaaaagaaaa agtaaaatga tgtaaataat atgatatgat ataagatgta gcaaatttag
     1621 taaataatta tttagatatc ataatcaaat tagcaacttt gcacaatgta aatattacaa
     1681 taaaataatt gatttaagga gtgaaggttt tgagtgaaaa taatataata agaaacactg
     1741 ttttaaatgt cacagcaagt tttttaaaac aagagtctaa aataaatgaa aagctagatg
     1801 gtgttttgga aaagaaattt gaaaaagtag aatttaatga agcaaaatat gcagagcttt
     1861 taaaatttaa tatattgttt tataagacat tagcaagaaa tacagaacca cttattggca
     1921 aatggatagt agataagtac atacctgaaa tagatgaatt agaaaaagat ttagagttaa
     1981 ctacagcaaa atgtagaaag tatgtaaata aggctatgaa agagggatta gactctctaa
     2041 aagccaatga tttaaatagt tttttagctt atgataaaat ggaactatca gagagaagaa
     2101 gacgtttaga aaaggattat aaggttttaa acctatataa agaccttctt aatatatctc
     2161 ttagaaaaat aagtttagaa aagaaagaat gtggagattt atttcttaaa aatcaagcag
     2221 atgcgaaaag agaattaaaa agagaaatta tattctgtgt aaacaaaata ttagctagta
     2281 ataaagatgt ggtacctaat aatgtggaag agaataacga acaaaacaaa gtagaaataa
     2341 aagcaactga aattgaggat ttgcaattag gtaaagataa ttcagaaaat gacatgctac
     2401 taaatgaaat taaaaattca aaagtaaaac atgaatcaaa atcaaatgat atagaatcga
     2461 agtttataga taagttaaat agcttaaata atgaaagtat atctcaaaca atacacaatg
     2521 aatataagaa gttatgtgga ttagaagaac ttcattctgt tgaagcatat ggttttggca
     2581 aagaaattat taaagatttt gcttgtgcaa cagttgtatt agaattttta aagagaagaa
     2641 atagagacct tatagaaggt gcaatgagac tgactataat tggagaattt ggtcctgaaa
     2701 attttaagga atttgtggac tatgtaatta aaaataaaac agaaattagt gaagatacat
     2761 ggaataaagc acagaatcta ataaaagata actatagtga attagaaaat catgaaattg
     2821 catcaaaaag aactagaaga aataaagata tcgatattga agaatacatt tacatgataa
     2881 aaaatgcaga taaagatatt tgctttagaa gtagtatttc aatagaagat gatgctgaag
     2941 aagggactaa agaagaagta gatagtaata atcaagatat aggtgacgtt gtagaagata
     3001 aagatactac agataaagag tacgacagca ataaagaaga tataattgaa ccagaaaata
     3061 aaaagagtaa aaagaaggct aaattatttg gatttattaa aaaagacaat gaagaagctg
     3121 aacaagaaga agagaattta aatgatattt ctccagatat aattttagat aaaccagttg
     3181 aaaatcatca agtgaaatca gaagaaatag agcaaaatga attgaaagaa ataaaacaag
     3241 aagaaccaag tcaacatata gaagaagaac gtagtgtaaa aatagaaaaa ccaataaata
     3301 ataacttaga tgaaaaagta tcttcaaata atgaatcgaa gcttgaaaaa gaaagtaaaa
     3361 acttagaaga taaaaaagca aaagaaataa aagaagaaaa attagaaaat gaaaaatcag
     3421 tagtaatacc tattaaaaag aaagaaaata gtaataaaaa atctaaaaat tcttctaagg
     3481 acaaatatag agaaaacaag aaagaaatga aaaattatgt atcagataaa gaagattctt
     3541 tagatgatga agaggttgtt tctaagaaga gtagattaaa agaaactatt atagcagtag
     3601 ttatagtggt tattgttggt gtaggatatt ttataacagt aggcaacaat aagaaaaatg
     3661 ataaagagaa tattccaaag tcatcaactc aacaacaagc taacaataaa ttaactgaag
     3721 aagagaaaaa agcacaagct gaaaaagaga aaaaagaagc agaagaaaag gcaaaagctg
     3781 aaaaagaggc tcaagaaaaa gcacaagctg aaaagaaagc aaaagaaatg gaagcatata
     3841 aagatggtaa aggtgtatat tacactgttt atgcaggttc acttaaagtt gaaaaaacag
     3901 caaaagaaac agcaaaagaa tatgaagcta aaggtatttc ttcaacaata attcaagaaa
     3961 atggatacta taaaataaaa ataggtgatt attctcaata tggagaagca caagaaaaat
     4021 gtaatgaact agctaagaag tctattgata catatatagc tatgtatgat aagtactatg
     4081 attataagtt agaagaatta aaagaatcag ctccttcttt gagtgctgaa gaacttaaac
     4141 aaaaatatga agatttaaga agtgagttaa agaacaaatc tggatatcgt gaatatgtta
     4201 aacatttaga taaactttat gaagaaatag ttgaaggtgc ttagagcatt ataaaaaagg
     4261 agaaactatg tctcagaata aaaagtatta aaaaaaatat tatttgtttt gagacatttt
     4321 attcaccttt ataaaatact tataattctg tttaggtggt gaaggtatgt tgaaattagg
     4381 agaaaaaatc atatatgagc tttcagatgg gtttgagctt agtggcataa gtagatactc
     4441 aaaagaatat aaaaagcttc atataacaaa tctagggaat ataataatca gcaaatcaga
     4501 tgaagttaat gaggatacag gtgtaaaata tatatatagt ttttcagaca ataaagaaaa
     4561 attagaggca gttttagaag attctcaaat aattgtctat ggaaataact tgccttttta
     4621 cataaaaagt gaaaattcaa gtaaaaatgt tacagcaaat ttgactatga aaataacttt
     4681 ggatgaatat gatttaatct gcaaaagtca aagagaattt atattctatc taaaggataa
     4741 tatgactata ttaagtttag atgacaataa gttttatatg ggtggaatta ataaagataa
     4801 tgagaagttt atatttatca gtgggaaaaa tagatttgaa ataaattttg atgatataga
     4861 aagatacatt ttagaagata aaagagtgtc attgaaggga tactttcata tggaaagaga
     4921 ggggattata gtaaggtctg tatctatatt taataacaat atagatagtg tagtcccatc
     4981 tgatttaaat gagagagtta aagataacca aaaaatagga aatcttccta aagattgtga
     5041 aatagtattc tgcaagatat caggaaatat agatggattt gattataaaa acacaaacat
     5101 gcttttagta aaatatcaag accaattaat ttttataaat aagaaatcta agaagactat
     5161 tgtaaagtca gcgaaagata attgttctaa gttaaattta ggagaagata taatattata
     5221 tgataataaa aatgtattta acctacatat aaatgataaa aatagagaaa ttatgcaaat
     5281 agatgaccta aaagatatag aaaatgaaat agtgggatat acattaaaac atgctccatt
     5341 ttttattcaa gaagatttcg atagcttgac tattctaaag tcttttcaaa aagaaatcat
     5401 atctataaaa aatagtgata taaaagacat tgtaattaat aaagaacttg aaaacgaaaa
     5461 ttctaatttt gtagaaacgg aaataaaatt taataatcaa aaagtacttt taaacttaag
     5521 taaaagtatg gttcaaaaac ttatgcaaga tgtatttata tatgcaaagc aacctctact
     5581 taaagaaaat tctattgaag tgatatataa gaattggtct aaagctatga atgatatgat
     5641 aatatttaat ttctttggaa atatttacta tatgaaatct gaatttgata agattttaga
     5701 aaaagagtta aatgatgaaa taagaataga agttataaat tcactttata agcaaataca
     5761 agaacaaaga aacaatttag atttattgtc agcatatatg ccaagaatat tagaaaatca
     5821 agaaatagat ttgtttgaaa agtataatac taaacttgat gtacaagtgt ttaagcagat
     5881 taaaaatcta ttgtctgatt tatcatataa tataagcagt tatttaaatg aagttgaaaa
     5941 aagtttagac aatatcatct ttgtaatttc aggagaagat aagaagaaat acaattatag
     6001 aatgttaaaa gaaagtgaaa gtgcaagtct tgatgtattt ttaaaacaag ccatatcaag
     6061 attaaaccat ttagtagaaa atatgtatcc ttattatgta gatgaaacta gtagggaaat
     6121 gtttaagtta tttgagttat tgtggaaaaa ctatagaaat attgatgatg atagtataaa
     6181 agaaatatta ttcgagagaa taacaaatac atatgtattt aaacaattga cattaaataa
     6241 tagtacaaaa gaaagaagaa aagacataat tgaaaaaata tataactctg ttgattatgg
     6301 aaccaataaa ctagatgaaa atatgttttt cacaggagga ataaagtatg tcaagtaaat
     6361 acaatgtttg gacttttaac tatgagttct taggattgga ctcaggggat gaaaaaaata
     6421 atgaagttta ttacgagatt gatttagatg aaattttaaa tgaaaactat atagatgaag
     6481 atatagatag tggtttagat tctgatggaa atagtatttt aggagaatta atatcagaaa
     6541 tggatataga tgaggatgtc agtgttgata tgacatatca agaactagaa gttgacttag
     6601 aagatttaga ttcttatcta gatgaagata tagatagtga tataaaaggc atcttagatg
     6661 aaatttagta cctgtataag ttttggataa aatataaaca atacaatatt aacttataaa
     6721 actaaaggta gatgaaattt catctacctt atattatctt atagcattaa atattgggat
     6781 aatatagagt ttgaagaaaa agtataaata tggtatatta atttggtaca atagaaaatt
     6841 tacgaagaag ggtgaaaaaa tgcagatgac agttaaaaaa gcaataatac cagcagcagg
     6901 gctaggaact agatttttac cagcaacaaa atcacagccc aaagaaatgc ttcctatagt
     6961 agataaacca actttacagt atataataga agaagctata gaatcgggaa ttgaagaaat
     7021 tcttataata acaggtagaa ataaaaaatc tatagaagat cattttgata aatcagttga
     7081 attagagtta gaactagagc aaaaaggtaa gacagagatg ttagaaatgg taagagacat
     7141 atcaaatatg gtaaatattc attatataag acaaaaagag ccaaaaggtc ttggacatgc
     7201 aatttactgt gcaaaaagtt ttataggtga tgaacctttt gccgtattat taggtgatga
     7261 tatagtagat tcagatgttc cgtgcttaaa acaattaata gatacttata atgagtataa
     7321 aacaactgta ttaggtgttc aaaagatagc taaagaagat actaataaat atggtatatt
     7381 ggatgtaaaa catatcgaag atagagtata taaagttaaa gatatggttg aaaaacctgc
     7441 aattgaagaa gctccatctg atatagctat acttggaaga tatataataa ctcctgcaat
     7501 atttagcata ttagagaaac agacacctgg taaaggtgga gagatacaac tgacagatgc
     7561 acttcaaact cttggaaaac aagaggctat ttatgcttat aactttgaag gtagaagata
     7621 tgatgtggga gataaaattg gttttttaga ggcaacaata gactttgctc taaagagaga
     7681 aaatttaaaa gatgatttaa tggactatat gagaaaaaaa gtaagtgaaa aataaatatt
     7741 agaaaagagg taattacaat ggcagtttta gtagctggag gagcaggata tataggaagc
     7801 catacagcaa tagaactttt agaatcaggt tatgaagttg ttatagttga taacttaagt
     7861 aatagcaact caatagtggt tgatagaatc aaggaattat ctaaaaaacc agtaaaattt
     7921 tataatattg atatcagaaa taaagatgaa atgcatgttg tatttaaaga aaataatatt
     7981 gaatcaatta tacactttgc agctttaaaa gcagttggtg aatcagtaga aaaaccaatt
     8041 gaatattaca gcaataatct aataagtacc ttaaatttat ttgaattaat gagagaatat
     8101 ggtgttaaaa agtttgtatt tagttcttca gctactgtat atggagaccc acatacttgt
     8161 cctatattag aggattttcc actttctgta accaatccat atggaagaac taaacttatg
     8221 atagagcaga tgttagtaga tatatcaaaa gcagataagt cattggatat agctctttta
     8281 agatacttta atccagtcgg tgctcataaa agtggtagaa taggtgaaga accaaatgga
     8341 gttccgagca atctaatgcc ttatataaca aaaatagcag taggtaaatt gaaggaattg
     8401 agtgtttatg gtaatgacta tccaacacat gatggaactg gagttagaga ctatatacat
     8461 gtattagatt tagctgctgg tcatgtaaaa gcattacaaa aattagaaga aaatccagga
     8521 cttgttgttt ataatttagg aactggaaag gggtatagtg ttcttgattt agtaaaagca
     8581 ttttctaaag caagtggaaa agaaatacca tataagattg taggaagaag ggctggagat
     8641 gtagccatgt gttatgcaga ttcttcaaag gcagaaaaag agcttggatg gaaagctaag
     8701 tatgaacttg aagagatgtg tgaagattca tggagatggc aaagtatgaa tcctaatggg
     8761 tatgaagagt agaatacata cttatatgta taaatgtaac aaatttgtaa atataaggta
     8821 ttggtaattt tatgttataa ttagacacat gtagtaatgt ttctaaaaga gggggaagtt
     8881 atagtgaaaa aaagtctaaa aaagtattta gtactagcac tgactttagt tttagtattt
     8941 gcatgtggcg taccagaatc aagcgcagcc agtaaacatg tgattatagt aaattcaaga
     9001 aaaaatactc taggatattt tgtaaataat aaacttgtaa aagaatttag agttgcaaca
     9061 ggtaaaaagg ggtcagaaac accaacaggg aaaacaaaag tagttaacaa gataaaaaat
     9121 agaccatatt ataaaggtaa tatacctgga ggaagtccaa gaaatccatt aggagataga
     9181 tggatgggat tagcattaaa aggaacttat ggagatacat atggaataca tggaaataat
     9241 aatgagagtt ctataggaaa gcatatttct ggtggatgta taagaatgca caataaagat
     9301 gttagatggt tatttgacca agttcctgta ggttcagatg taattataga ttatagtaac
     9361 gacagctatg taaagatagc ggcaaaatat aagataaatc taaatcaaac aggatggaaa
     9421 acagaaaatg gtaagaagta ttatgtaaaa tctgatggaa cataccaaaa gaatagttgg
     9481 ctaaaagtaa atggaaaaat gtattacttt gatgcttcag gagtaatgca aacaggatgg
     9541 aaaacaatta ataacaaaaa atattattta ggaactgatg gagcaagagt atctggatgg
     9601 aaagtaatag acggaaaaac ttattacttt aactcagatg gagtaatgca aacaggatgg
     9661 caagaaaaga atggaaagaa atactatcta ggatctgatg gtttagcagt aacaggatgg
     9721 caagaaatag atggtaataa gtattacttt gacaaaacag gaataatgca gacaggatgg
     9781 caacaaatag atggtaagtc ttactattta gacaaagatg gaaagatgct aactggttct
     9841 caaaaaatag atgggaaaga ttatactttt aatgaagatg gaactataaa tcctacatgg
     9901 gatacaatta taggtgcaaa tagatttgat acagctaaaa agataagttc agttggaaac
     9961 tggaatgctg atagttcaga tactgtaata ttagtaaatg gtaatgcaat agctgatggt
    10021 ataacagcaa ctcctttagc aagtagctat gactcaacaa tactacttac taatacagct
    10081 aatttaccaa ctgaaactgt tgaagaaatg aagttattag cacctaaaac agtaatcttg
    10141 ataggtggag aaaatgcaat aagttctaaa ttagagcaag aaataaaaac tactttcaac
    10201 acagaaacaa agagaatagc aggtcaagat agatatcaaa ctgctacaag aatagctgaa
    10261 gaacttggaa atcgagaaga aataaaaact gcatatatgg tttctggaaa tggggaggca
    10321 gatgctttat ctgtagcttc taaagctggg gaagaaaaac aacctataat attagtcaat
    10381 aaagatggaa ttacagaaga atcttataaa tggctaacag aaagaaaatt agaaaatgca
    10441 tactttatag gtggaccaag tgcaattaac gattcagtaa tagcaaaaat gaatgatata
    10501 actactgaag atatttcagg aaatagaata tatggagata gtagagtaga tactaatgcc
    10561 aaagtgatag aaaaattcta tggagatact gatttacagg ctgtattagt tagtaaatca
    10621 gatgctttag tagatgcttt atcagctgga ccattagctg taaaattaca ttcaccaata
    10681 gttttaatgg ataattcagg attatcatca gagcaacaaa gagtatttgc aaataaaaaa
    10741 gttgaaactc cttatcaaat aggaggcgga gtatcttata tagtaatgga taaattaatg
    10801 gatattcttg caaaatagta aaaatatata ttgaaaaata attataattg agatgtgaaa
    10861 ttcaatcaat aaaagcttga ttgttttaca tctcaatttt ttagtataaa attaagttta
    10921 agttatataa aaatcttgga atatttttaa aactcatata aaatgaatat agatgctatc
    10981 atcatatgtt aagagggtga gtaagattat aaagaaaaaa tatataatgt ttattgatga
    11041 aagtggaaga gctgatataa atcatgaaga cccatttaca ttgacaggag taatttttga
    11101 atataaatat gcagtaagtc aaggcgatta tgtatgttct ttgaggaaag aaatggatgc
    11161 atttaaagag tattgttttg gaaccagtaa cataggaata catttgacag atatatcaag
    11221 aaaatcaaga gcatttgaga agtttgatga ttcacagatt aagttattct atgatgagtt
    11281 gcctttattt ctatctagat tagagtgtac tataatatca gtaacagtag ataaagctag
    11341 attaaagaaa tattatgcac cttcaaagga accgtatgtt gtggctttta tacatgttct
    11401 tcagaatttt tattcatttg taaataatga aactgtagaa tctgcacgaa tagttataga
    11461 gtcaagggat gatgtctcaa acttaaaagt acaaaaggcg ttttttgatg tatttaataa
    11521 tggaacaata tacttagata tagatgaaga attaagagat aaggttaagg gttttataat
    11581 tgccaaaaaa gaagatgctg actatagaga aggtttagaa atagcagata ttttatgtaa
    11641 tcctcttagc agagcaagaa gagggttaat agaagctaat ccaaagtgta tgcaatatgg
    11701 agaaaaaaac aaaatattca aatctgtcag aaacaaaata tatactccaa cgagtgtgaa
    11761 tgatataaga aattggggat ttaaagaagt tcctattgta gagcctgttg gaccatggct
    11821 tgaaaaaatg cgttagatac aattgacaaa ttttaaaaaa tctgatataa tgtaagtaac
    11881 ctagttattc aggaactgaa tccagttgct gttgtataac gataattact gagactcgga
    11941 tgccgactgt cagttaggaa tctatacttt taaaagtata gattttttta ttttataaaa
    12001 agaataaaag aggatattta aaaataaccc ctttattaat aaattataat tgagcgtttt
    12061 taatgacaaa gtttttaaag tttttaattg caggaggcaa atatctatct tttataaatg
    12121 ctaagtaaaa gtttctttcc caacttgggt gaataatctg aattactttt acttttgtaa
    12181 agctaagcat attcatattt gggactacag caattccgaa attttttgca actaatccag
    12241 caattacttg gtcttcctct acttcataga ctatattagg ctgttgattt atttttttaa
    12301 acatatcatc aattatatat ctaagaccac ttctctgatt aaatactatt tgaggataag
    12361 gtatggtttc ttttaaatct atagtatcct ttgcagctag tggatgacta tatggtacaa
    12421 ttagtactaa atcttgtttg gcaacaggta taaattcaat tcccttttct ttttcaagtt
    12481 tcgaacaaaa tgcaatatca tattttcttt ctttaagacc ttgaataatg tcagtagtta
    12541 caccagtatg aaatttaaaa tctattgatt tagcaggatt agattttaaa aatttgtgca
    12601 ctatgtctgg gataaaatca gtaccaagtg ttctaagaaa agctaagtct atttgtcctt
    12661 caccagtacc agttattttt aatgatttta cacttgaatc taaaatttct aatgattttt
    12721 ccacatcttt taaaaatatt tttccatact tagtaaggac tatatttcta ccttcttttt
    12781 caaatagagc caccccaagt tcattttcta gtaaagaaat agcatgactt aagcttggtt
    12841 gtgttataga taaattttct gccgcttttg tatagtgttc taaatgtgcc aatgtaacaa
    12901 aatagcgtaa gtgatataaa ttcaattttt gttcatcctt tcataggtat ttttatttat
    12961 atatttgtag aagttaacct ttaagatatt tttacatttt tattatatat gattatagag
    13021 taagaataaa agcttttaaa aaaatttatc gttttttgtc tgaattataa gataaatata
    13081 tttatacgac ctaatagaaa aatacaagaa ttatcttata aataaaatct ataaacaaaa
    13141 tctatgaatt aataggaaat tatcaatttg ttattagtaa agtctcgtga tacaataaat
    13201 ttataaaatc tagataaata gaaatcaaaa aatactttta tttttaaggt aaaataatac
    13261 tactagtagg ataaataaaa atataaaatc aaaaatacta ttaattataa agaaaataaa
    13321 gggggcaaat ttaagctatg aataatcaaa aaaatcttaa tattccaatt acaattagtt
    13381 cttatacatt gggaacagaa gtttcattcc gtgatagagt tcgtattgca aaagaagctg
    13441 ggtttgatgg tattggattg cgtgctgaaa attatattga tgcaaaaaat gcaggtgtta
    13501 cagatgaaga aatgattgca attcttaatg aatatgatat gaaagttaca gaagtagaat
    13561 atataactca atggggaaga gaagaagata gaacggaagc tcaaagagaa aaagagcaaa
    13621 atgtttatca tatggctcac ttatttaatg ttaaacatat aaattgtgga ttattagaga
    13681 tgataccaga agaacaaatt ataactgcat tgggagaatt atgtgacaga gcaggtgaac
    13741 ttattatagg tcttgagttt atgccatata gtggtgtacc agatttggct actgcatggc
    13801 gtgttgtgaa aggatgtaat cgtgaaaatg caatgcttat attagatact tggcactggg
    13861 ctagagcaaa gcagacagca gaggaccttg cacctgttcc agcagataag atagtatcaa
    13921 ttcaagtgtg tgatgtttta gaaactcctt atgaaaaact tagggatgaa tcactacatg
    13981 accgtttggc tccaggtgaa ggatatggaa acacagagga atttgtgaaa ataataaaag
    14041 aacacaatat atcaccaaga gtcatagggg cagaagtaat atctgattct ctaatatcta
    14101 aagggttatc cactgctgct gaaactgtat ttaatgcaac taaaaaagtt ttggataaag
    14161 catggtctga agtatctcca aaataaactt atataatata aaaatataca gagtattata
    14221 atataaaact tgaaaggaag gaaaacctta tgaagattag ttctatgttt acacctataa
    14281 gaattggttc aatgacagtt ccaaatcgtt ttgtagttcc ccctatggga aacaattttg
    14341 caaacacaga tggtacttta agtgaaactt ctaaggctta ttatcttgag cgtgctttag
    14401 gtggttttgg attaataact atagaatcta gtgttgtaga caaaaaagca aaaggaggtc
    14461 ctcgtaagcc ttgtttatat gatgatagca caatagatag ttttaaaaat gtaatagatg
    14521 cttgtcatga tgcaggttcg aaggtatcta tacaattaca acatgctggt tctgaaggaa
    14581 atgaaaaagt agcaggacat ccattaaaag ctgcttctgc aatacctgca tcaaatggtc
    14641 gtaatacacc actagcaata acaacagaag aaatatatga acttatagaa tcttatggag
    14701 atgctgcatt acgtgcacaa aaagctggtg cagatgctgt tgaagttcac tgcgctcatg
    14761 gatatctggt tagtagtttt atatcacaaa gaacaaataa gcgtgtagat gagtttggtg
    14821 gatgttttga aaatagaatg agattacctc gtcttatcat tgaaaatata cgtaaaaaag
    14881 taggaaattc tctagcaata ttatgtcgta taaacagcac tgatgatgtt ccaggaggaa
    14941 ttgatgtaca cgatagttca gtaatagcag catatctaga agattgtgga atagatggac
    15001 ttcatgtttc acgtagtata catatacatg atgaatatat gtgggctcct acgactttac
    15061 atgctggatt cagtgcagaa ttagttactg aaataaaaaa agctgttagt ataccagtaa
    15121 taacagttgg acgttataca gagccacagt ttgctgagtt aatggtcaga caaggaagat
    15181 gtgatttagt agcattcggt agacaaagct tggctgaccc agaaatgcct aataaagcta
    15241 aaaatggaaa actagacgaa atgataccat gtattgcatg cttacaagga tgtgtaccaa
    15301 atatgttcca aggcaaacct atagcctgtc ttgcaaatcc tatattagga catgaagcag
    15361 agcttaagcc agctgaaatt agcaaagaag ttcttgttgt tggtggaggt gttggaggta
    15421 tgcttgcagc atgggtatgt gctaaaagag gacataatgt aactttagtt gaaaaatctg
    15481 aagttcttgg tgggcaaatg cgtttagctg catatcctcc agggaaagga gatattacta
    15541 acttagttag aagttatatt tcaaaatgta atcaatatgg tgtaaaaata tgtactaata
    15601 cagaagctac agtagaactt ataaaggaga aatcacctga tgtagttatt atagctactg
    15661 gagcaactcc acttgtactt cctataccag gaatcaatga ttcaggatta attcatgctg
    15721 tagaccttct tgatggtaaa aaatcttgtg ggaaaaaagt acttgttgtt ggaggtggaa
    15781 tggttggatg tgaagtggca gccttccttg gagaacaaga acatgaggtt actgttattg
    15841 agcttagaga agaagttggt gcagatgtaa tttcagaaca ccgtaaattc cttatgaatg
    15901 attttgaaaa ttataatata cataccatta ctggtgcaaa agtttctaaa ttttatgatg
    15961 atggtgtcga ctatttactt acagatggca cagagcatga tttaaaaggt tttgattcag
    16021 tagtacttgc tatgggttct cgtaattacg acccattaag tgaagttata aaagaagttg
    16081 taaaagaaac ttatattgtt ggtgatgcag taaaagctcg tagggcatta gatgcaacaa
    16141 aagaagcttt tgaagtagca ttaaatatat aaataataaa taaatttttc tttgtaaata
    16201 actgaatagg ttatttgcaa agaaaatgat aatattgaga ggagattata gttatggaaa
    16261 tttcaggtag aacaggatta tttgcattaa taggtacacc ggttggtcac tctaaatcac
    16321 cagtgatgta taattatagt tttaagaaat tagatttaga ttatagatat ttagcctttg
    16381 atatcacagt agataaggta aaagaggcac ttttagcaat aaaaactttt aatataaaag
    16441 gagccaatgt tactatgcca tgtaaatctg ctgttacaga atatatggat gaactttctc
    16501 cagcagctcg tataattgga gcatgtaata caattgtaaa tgacaatgga aagttagttg
    16561 gtcatataac agatggagta ggctatgttc gtaatttaaa agaaaatggg gtagaagtta
    16621 aaggtaaaaa gattacaatt atgggtgctg gtggtgcagc aactgctata caagtacaat
    16681 gtgctttaga tggagcaaga gaaatatcta tctttaatcc taaggatgat ttttataaaa
    16741 gagcagagca aacagttgag aatataaaaa aagatgtacc agaatgtgtt gttaatctat
    16801 atgatttaga agatacaaac aaactttatg aggagataca atcaagtgat atattgacaa
    16861 atgcaactct tattggtatg aagccttatg acaatgaaac aaatataaaa gatactagtg
    16921 ttttaagaaa agatttagta gtaacagatg tcgtttataa tcctaagaaa acaaaaatga
    16981 ttgaagatgc tgaagctaat ggatgtaagg ctattggtgg attaggaatg ttattatacc
    17041 aaggagcaga agcttttaat ctatatactg gattagaaat gcctgtagaa gaagttaatg
    17101 aattatgctt taaatagata agagtaatat cttaaacaat gaaaaaacat acgtatttca
    17161 atatttttaa taataaatta caaattgtca tagtgggttt tgcctcatag tccagttaaa
    17221 tttgaagttt taactgacta tactttaaat ccattatggg gatgagttta ttgtacacaa
    17281 aaatgttaat aaattaacaa gaatgggaga aaaattatga acaataaaaa atattatcct
    17341 actgccatag cgttgtattt ttcatatttt ttacttggta ttggaatttc aattttagga
    17401 caatacaaac cagaattttc atcaatgtgg ggggctaaaa cattatcaga tggaacattg
    17461 gatgtaagta ttgttttagc tgttattgct gcactaggat tagggagact tatatcttat
    17521 ccatttgcag gacctatttc agataagtat ggaagaaaag taagtggtct tataggaaac
    17581 tttctacatg caattttctt tgttggaatt gtattttcac caaattttta tatagcatat
    17641 gtatttgcaa taattggagg ggcagcaaat tcattcttag atacctgtgt aactccttct
    17701 tgtatggaga tatttgctag tttaggaaca atagcaaata tgtttactaa atttacaata
    17761 gctttagcac aatttttgct tccttttata attggatttg ttgcagcaaa ttcaatatca
    17821 tttaaagtta tttttatagt aacagcgatt cttattgtag tagatgcctt tttgatagct
    17881 gtgttaccat ttccaccagc taataatgtt attgataaca aaggcaaaac agttaaatca
    17941 gagaagatga aatttacacc aacaagtata gctcttgttt gtattggatt tacatgtaca
    18001 tctacatttg tattatggtt aaattgtaat caggaattgg gtaaattgta tgggatggct
    18061 gaccctacaa aaattcaatc cttttactca atgggagtaa tatgtgcagt attaataact
    18121 tctttactta ttaaaaaata tattaaacca ataagaatat tagttatata tcctataata
    18181 gctttactta tgctattagt tgtatatttt gttcaaactc caactatttg tatgttaggg
    18241 ggatttgtaa taggttattc agcagcagga ggtgttcttc agttaacaac gtcaactgca
    18301 aatgaaatgt ttccaactaa taaaggaaaa ataacatcta tagttatgat tgcatctagt
    18361 atagcaaact atgttatttt aaatatagca ggtattatta caaaatcagg gggagttaat
    18421 ggaccaaaat atgttgtatt gtttaatgtg gcaataacat ttgttggaat tttacttgca
    18481 ttgtttgtaa acatgagata tgaaaaagaa aaagtgtatg attatgatgt ctaatattag
    18541 tataatatat gcatagagaa gtctaaatct aggatagatt tttattaaaa gtaattaaaa
    18601 ttaataagga tattatttac agttataaga tagggtattt acataattaa taataaggat
    18661 attactagaa tttcaatttc tagtaatatt tttttgcgta taaatgtaaa cttgatgaaa
    18721 taagtagtat aatcaatata aattacatca tgtaaaggag gataatttgg tggagaatgt
    18781 ttttaagcga ttgcaggaat ttaatggtta tgatggatac aaagaatcat ttgaaatgaa
    18841 ttacctatgt atatatgaaa gtataccgtt aagagaacaa gtagagcttg caaataatct
    18901 agtagatgaa attttaaata tgtataaaag tgaatctaat gaaatttatt tattggaggg
    18961 tagtaattct aagtctttaa tttgttattt cgaaattttt atgaaaaaga taaatacttt
    19021 ggtaaaagaa atgattattg atgagaaatg gttatataaa ttaactaaag aattaatata
    19081 taagagtaaa aaagttgagt atgtaaaact agggttagtt ttaagtgaga aatatctaaa
    19141 tgtagaaaac ttaagagaag ttgtagatac attttctaaa tctggagaat acgtatttta
    19201 tctgagtaat actattaaaa aacttgaatt ttacaataca tatttattta atttatctaa
    19261 aaaggctaca ggttcaataa aagtatttgc tattgttaat atggaaaatt tagattctaa
    19321 aataaattcc tatctaattg aagatggtta taaggataca aagtacgaac gattattgat
    19381 gaactatatt atttcaattg tagatttgaa tgaatatctt gaaaaacgag atttagataa
    19441 agaaaagata aataatttag cacgtcttat atgcaattac ttgctaagtg tagaatttaa
    19501 atatataggt aataaattag aattagtgaa tcgattttta cctactgtag taaattatgg
    19561 gactaacttt gaaagtttat attcaatttt cctaatagct ataaacgtct taaaagatga
    19621 aaatatagag tgcaataaga ttgaatttga aaaagaaata aatggtatct tgctcagtga
    19681 aaaatggaaa aatatatatt ttgaagcatt aagagatgct agtggaaaaa cagaagatat
    19741 tataaaaatg tcagaaattt atgatgtaaa cttatctttt gatgacttgt tgccatatct
    19801 aaatagagat attagagatt ttgaggtata ttggcatata tctaaaaagg gaacgacaag
    19861 ttctagatta aaattattaa atttttttga agagacgttt aaaatagatg atttaattgg
    19921 aaaaatgaaa gatatagaaa aagataaatt gactcaagaa tattatgatg atatgttatt
    19981 ttttattgtg cttaaaggaa gtaaatcact atatcctgaa ggaaagaata tatctttaaa
    20041 aggaatattt ggaaatataa atgaagtaag aaaagaatcc ataaatatct taaaaagata
    20101 cagagagaaa ctatctcttg aagaattaaa aattgttaaa gaagcgtatg aaaaagaaaa
    20161 aaatgttata ttgaaggatg aattaagaag agtattatat gaaagtaata atttaaaaaa
    20221 agaatttgta aatattgaaa aaataaaagt agatgaacat ggtaaggata tctatttgac
    20281 ttcaatagct gttgctggtt caaggtttag aaatagagaa tatcttgaaa aagaattgga
    20341 gaaaagtaag atatactatt taactagaga gaaagataat ctatatgatg aaaaagctat
    20401 taaaatagtt ggtgaaactg gatatgtgat aggctatgtc ccaagaaaag aaaactatat
    20461 tttgagcaat ttattagatg gaggaaaact gctgtattgt agagtaactg aatataattt
    20521 atatgaagat tgtatctacg caaatgtgta cttgagttat aaagatgtaa ttgaaacagt
    20581 tgaaaactct ttaaagatgg ttttagataa gagtagaata aaacttataa actaagacgt
    20641 ttatatattg cttagatgat gtaatcctaa ctgattggtt attttttctg gaattatggt
    20701 gtattttatg agcaatgcta atgaatataa aataaaaaaa caattgtttt gtatatatga
    20761 tgtatataaa tatatttata tattcatatt tacaaaacaa ttgaaattta tgttatttta
    20821 taattttaaa tttagatgga attttaactt ctgctttatc ttttatttta gaagcttgtt
    20881 ttttaacttt atttaataat tcagattcat ctacaactaa tacttttctt tccttcatca
    20941 accatttacc atcacaaata gtagagtcta cattttcact agtcatagaa taaactatat
    21001 ttccaattgg attatgcatt ggtaaacaat gaattgtatc tggatttaga ataatcatat
    21061 cagctttttt tcctacttca agactaccaa tttctttttc tagtaaagca cattttgctc
    21121 catttatagt agccatttct aagacttctt cagctggtac gacagttggg tttaaagttc
    21181 ttcctttatg tattagtgat gtaagataca tgtccctcat aaggtccatt ctattatttg
    21241 aaggagctcc atcagtacca attgaaacag gtattccttt ttctaacatt tcaggaattg
    21301 atgcaaaccc tagaaccact ttcatagctg aacctgggtc atgagaaact tttacatcat
    21361 gtaatctaaa taaatcaatt tccttatgag taagccaaac tgtatgagca gctaaaagat
    21421 ttggtcctaa tacacctagt ttatcaaggt attcaactgt tccaactcca ttgttttgct
    21481 ttacaaatga aatttcatca gctatttcag caatatgcat atgtatacct gtattgtatt
    21541 tatcagctag ttctttagtt ctaacaagta attcttcagt tgtattaaaa atagttctta
    21601 atgcaaacca tattttaatt ctctcattag atgtattatt aaacttatgg aataagtcta
    21661 attgagtgtt gatttcctca tcagtagttt tttgccatgc ctcaggaaga ccatctcctg
    21721 tatccataac tgatttagct aaacaggctc taagtccagt tttatcaaca gcttcaacca
    21781 tagcatctac atattgacca ccagattcta aaaatgtagt gacaccagat tttatcaatt
    21841 caacacaaca tgcagtagat gaaatcaagg aatcttcata attgaagcta ctttcgtatg
    21901 gccaaattct ttctctaagc caagttaaaa gtacaacatc atctgcaaga ccacgtccta
    21961 attgttgaga taagtgaaca tgagtattga ctagccctgg cattagtatt tttcctttag
    22021 catcatatat ctctgcatct ttatctacaa tattaatatc aaacttacca acctctttta
    22081 taatattatt ttcaataagt atgcttccat tttcatatac ctctctatct gcattcatag
    22141 taattagata tgcatttttt ataagtaatt gtgacataaa caccactcct tttctatata
    22201 tttttatatc tatatattat gataataaat tttctataca aagttaatag caaaatcaat
    22261 ttacatataa agtgattttg ctatttataa atttaaaata aataagattt tattctatat
    22321 aatttaaaat attgacctag aactatttaa aaatattaac ttagaactaa gtttacaact
    22381 gcaagtaaac ctataatcca aagtgtaata ctgattttat cagtttcttt agctactaca
    22441 tgcattatta tatatgaaat aaatccaaag cataaaccaa tacttatact ataagttaaa
    22501 ggcatcaata aaactgtaac aaaagcaggt acagctattt tgctatcagc aaaatcaatc
    22561 tgttttatgc tttcaaacat gaatacacca accattacaa gtgcaggagc tgcagcgtaa
    22621 gtaggaacta taccaagtaa tggtgtaaat ataagtgtag ctaagaataa tgctgctgtt
    22681 actattgaag caagtcctgt tcttgcacct gctgcaatac cagaagcaga ttctccaaat
    22741 gttgtaacag tactagttcc taagaatgag cctattaaag tagaagaaac atctgcatat
    22801 aacattcttc ctaaatcttt tatttcacca ttctcatctt caagacccat ttgtttacaa
    22861 caagtaataa gaaatgctaa tgaatcaaac atgtctataa acatgaaaga gaatataggt
    22921 ccaattaatg agaatttcaa tgcacctaca atatctaatt taaaagcaac tggtgctata
    22981 ctaggaggtg tcgagattat tgctgttggc aactccacaa atccaaatat aacagatatt
    23041 attgttgcaa ctactatact tatcaatatt ccacctttaa cttttttata ttctagtatt
    23101 gccattaaga taagagcaaa aagagctatt aaaactgttg gtgtaaaatc tgcaagtgaa
    23161 actatagtat ctggattagc tattataaca cccatatttt ttaaaccaac aaaagcaagg
    23221 aaaagaccta tacctgctga agatgctact gccaattctc taggaattgc gtctgcaatt
    23281 gtctttcgaa gacctgttac tgcgagtgta aagaagacac atccagatag aaaaactacc
    23341 ccaagacctg tttgccatgg gattcctgca cctataacca aagagtatgt gaagaatgca
    23401 tttaatccca taccaggagc tagagcaaat ggtgcatttc ctaaaatcgc aaatataagt
    23461 gtaccaatgg ctgtagctag tatggtaact gttataaggg cggctttatc cattccagct
    23521 tcagataata ttgctggatt tacgaaaact atgtatgcca ttgttaaaaa tgtagtaact
    23581 ccacctatta cctctgtttt aaggctagag ccacgttcgc taaatttaaa cattttgtct
    23641 aaaaagctta atgatgaatt atttccacct ggttgtacat tgttagtgtt tggtaccatt
    23701 tttacctcca aaaaacttta agatataaac aaaaaaatat atattcatat agatagaata
    23761 gaacatatat tcagagttga cattctattc atagaaaacc catttaaggt gagtttgtag
    23821 aaactattag accgtattac taatattata tgaacatttt ctatttgttt ttctgttgta
    23881 ttatatcgta atattgtatt atttacaata aatataataa aattattcgt ttttttgtcg
    23941 attttataaa aaattaaggt tatttattga aaaaaattac tttttccaat aattgaatat
    24001 gtatgaatat aatgtcaatt attctaactt gttttatact attaatggaa gtttattata
    24061 aatgagtttg tgatataatt ataaaagtac tgaatacatg gatatttcgt aaaaactttt
    24121 taatatatca aatatgtata ttaagttaat atattaaaaa aaataatatc aaaaataata
    24181 taatttatag tggaggggaa aatgactaaa attattaaag tgcaaaaacc taaatttaca
    24241 ggagaattag aaattattga aaatcttgaa gatatacttg aagatatatt taatgatgaa
    24301 aaaatattta ataaaattat agaaaatgaa gttataagtg atttagattc tgtaagagtt
    24361 agctttgaat cttgtatatt tagaaatgtg tcttttgaaa attgtaattt aaaaaagatt
    24421 gatttacttg atgtggtatt tgaaaactgc aatttatcaa atacattttt tgatggagga
    24481 agtatataca gagttgaatt taaaaatagt aaattgatag gagttagatt tgatgattgt
    24541 atacttaaaa acgttttgtt caaggatgtt ttaggtaagt attctaactt ttcattctct
    24601 aaatttaaga tagtttctat cttagattca aattttgaaa attctgtatt tcaagaagta
    24661 aaaggtgaca atctagtatt tgagtataca aatttaaaaa aagcaaactt taatggaact
    24721 aaactttctg gcatagattt tactactaat aatattgagg gaattgagat tggtatagat
    24781 gatattagag gagcaatttt tgatgtgtca caagcaattg atttaacgaa attgatggga
    24841 attatcataa aatgaaaaaa atattcataa aataaattgg gaaaacgtta acaatgtgtg
    24901 aatttttacc agattgacat ttttctgaaa ataaagtaag attatcttaa tattcaaaat
    24961 attttcaaag ggggtaattt agtgtgagta agcagatgag agatattttt atagttggtt
    25021 ttgctttatt ttctatgttc tttggtgcag gaaatcttat gtttcctcca tttttaggga
    25081 tggaatccgg caaagactgg ttaattcctc ttattggatt tgttgttgca gatgctggta
    25141 tagcaatgct tgttattata gcaacagcaa gatgtaaggg aagcatggat gatgtactta
    25201 ggagagctgg taaagggtta gcaagagtaa tgagtgtagc tgctctagca tgtttagcac
    25261 ttcttgtaat accaagaact tgcgcaacaa catatgaaat gggtattatg cctatatttg
    25321 gagaccatgg tccagtagct aaagctgtat tttcaataat cttctttggg ctaactttag
    25381 catttactat taggtcttct aaggttatag acataatagg taagtattta actccagcgt
    25441 tattattagt attatttgtt ttaatagtaa agggtataat ttctccagca ggacctatga
    25501 gtcctgagca tatgatagat aaaaatctat ttggtgaagg tatatcacaa ggttatcaaa
    25561 caatggacgc tctaggtgca gcatctatgg caactataat gttgatgtct ataatagcta
    25621 aaggatatac atcagataaa gaccaaatag gaatgactat taaagctggt tttgtagcct
    25681 gtgtatttct agcagtagta tatggtggtc ttacttattt aggtgcaaca gtttcaactt
    25741 tatatgatac tagtatacct caagcatctt tattagttga aataactagt atattgttat
    25801 atggtcaagt aggaaaggta attttaggtg taattgtggc acttgcctgt ctgactactt
    25861 ctacaggttt aacagcatca atatcaactt attttgaagg aataagtaag gcgagttata
    25921 aacaactggt tataggtata tgtgtagcta gtatgcttat atcaaattta ggtgttgatt
    25981 ctataatagc catatcagtt ccaatcctac aaactatata tcctgtttta ttagcaatag
    26041 ttgttatgga gttggctggt aaacatataa agaatgataa tgcttttaaa ggtgcagcat
    26101 atgttacatt agtgattagt ttattatcag ctataaatgg aatgacagga gctgttccat
    26161 ttatacaaag cttgccactt gcaggtttgg gctttaactg ggtaatacca gctatattgg
    26221 gtggaatagt tggtaacttt ataaaaagca acaaacaagt agcataataa tttgtaatta
    26281 atttaatttt ataatatatt aatttttagt actatgggta ggtttaatct aaacctaatc
    26341 tacccatagt actttttaga ttggattata atagcatgta tataattttt tataatataa
    26401 tttttctttg aagtatgata aaattagtaa tagtgataag aatgtacaaa tttaggaggt
    26461 tttaattaat gcttagaaaa ataacagcat ttatgctatc catatgttta attattggac
    26521 ttacaggttg tagtttactt gtaggcaaga aagataaaga gaaaattata gatgatttta
    26581 aagttgcagt ggtaactcaa ccattatctg aaaataaagt acaatacaat atggtggaag
    26641 agatggcaaa agaatatgag gaagagaata aaattgataa agacaaagat ggtcaaacta
    26701 aagttaaaca aactataaag catgttgtat tgccagagaa ttttacttct aatatagaca
    26761 gtgctattaa taagatagta aagttggctg acgataaaga agttcaggct attgtagttt
    26821 caactgacca agcagggctt ttacctgctt tacaaaaggt aaaggaaaag cgtccagaaa
    26881 taataactat ttctgcccct atgggagatg ataaaaacca attaagccaa tttgttgatg
    26941 tgaatctagg ggttagtgca gaggaaagag gaaaagtatt agctgaacgt tcaaaagaaa
    27001 tgggagcaaa agcttttatt cattatgcct ctacagatga tttgaaagat gttaatatag
    27061 ccaaaagatt agaaatgatt aaagagactt gcaaaaatat aggattgcca tttgtacaag
    27121 ttaatactcc aaatataaat actgaagaag acaaaaacaa agttaagcag tttttaaatg
    27181 aagatattga aaaacaagtt aaaaaatatg gaaaagatat aaatgtattt ggtgtaaatg
    27241 agtatatgga tgaagttata ttgactaagg ctttagaatt aaagtatata gttgcagagc
    27301 aaagcaatcc atcaccaata caaacatatc ctagtgttat gggtctaaaa atatctgaaa
    27361 aagatgctca aaattatgat aaaataaacg acatgataag tgaaaaggct aaggcttttg
    27421 gcatgtcaaa tagacttggt ggatatccta tgccaatgga tgcttttcta ccatcagtag
    27481 caatttatct tgctactgaa atggtgaaac aagatttaac acaagaagat gtatgtgacc
    27541 cagattattt agaggcgttt acagaattaa gatttggaat cggttcagaa tttactcctt
    27601 taacagaggt actttataat tatcaatcag taattttaag ccaattaatt tattaatatt
    27661 aaggaagtgt ctcaaaatga actttttagt ttatgaggca ctctttttct attaaatcaa
    27721 atatattttt atctttttaa caattaaaaa gaagcttatc cctatattga gatagcttcg
    27781 tttttaatat aaataagttt tattatttta taaaaaattt atagaaaaat aaaaaattat
    27841 aattatatat aaattttgat aaagtaaaga tgaattacta taggtttaaa ttatattatt
    27901 ttctattatt tttatgcctt tctcagttat tgatgagcct tttcttcctt tactagaaat
    27961 taagtatcca ttgcgtgtca aatattctag catatttctt acttcgtatt ctgtgacatt
    28021 atattccata aatttcatta actttgtcct ccccattggt ttcatgtgca atgattttag
    28081 gatagaaatg catatgtttt tgtcatattg gtttaaatca ttgaatatgg acatattact
    28141 tgacatatga ttattattta attttgaaga tatgttttga ggtaaatcat ttattgtaag
    28201 ataattggaa cccatgtaag ccatatattc aatacaattt ctcagttctc taatattccc
    28261 catccaagtg tatgaattta aagcttctaa aagactctta tcgagtttta tgtttttata
    28321 gggaagttct tttaaaaatg attctaaaag aagaggtata tcttctaatc tctttctaag
    28381 aggaggtaaa tctaaagtga acatacttat cctataaaat aaatccatcc taaatttatt
    28441 ttctataatt aatttctcta aatctttatt tgtggcagct aatattctca catcaattgg
    28501 aataatactt gtaccaccaa tttttctaat ttctttttct tgtaagactc ttaaaagttt
    28561 aacctgtaaa tcatgtggca tatctcctat ctcatctaaa aatatagtgc cagtgtgagc
    28621 taattcgaat aatccttttt ttccaccttt ttttgctcca gtaaaagaac catcttcata
    28681 tccaaatagt tcactttcaa gtaattcact tggtaatgaa gcacaattta ttgctacaaa
    28741 aggtttattt tttctatttg aatgattgtg tattgactga gtaaaggctt ctttacctgt
    28801 tcctgtttca cctgttatta atataggatt atctgtaaga gccatttttt ttgccttttt
    28861 aatacaatct tttataatag aactatttcc aataatatta ttaaatttat atttagctac
    28921 ataacctctt ttgacagaat cacttcttat tttttgttct aatatttcta tattgtttac
    28981 atctttcaat gtaattaagc aaccctctat atttttataa agataaaatg gttttttaga
    29041 aagtatgaat tttttatcta tttcgtctat gtatataatc atattatcga tatttaagtt
    29101 ctttgtaatt ttatctaaga aactatttgg catatattcc attaaggaag gtgattttat
    29161 aagtttttca tctagtccca acatattaag taaagactta tttacaaaag taaccttgtt
    29221 aaaggtgttg aaaaatatta gaccatcacc tatttcatca atggtcatgt aaagtatagt
    29281 ttttaattta gatatattat ctaatgatgt atttaagaaa tcatgactta gtgtctcttt
    29341 ggacaatttg tatagttttt ctataaattt ctcatttttt agttttaata ctactaataa
    29401 tgacatatat gtatctaatg agatttttct ccaacctaaa tcaacaatat tttttatgta
    29461 ttttggtata aatctaatct gacctggtgt tatagctgta tctaaatcat atatttcatc
    29521 acaatctgga tatgtcggta caaaatctat atgatttata ccaattttat atagataagt
    29581 agccatctca aatgctgaag ttttattggt tgtcataagt aacgattttg tacctggagg
    29641 tagtttcatc attttttcat atccaagttt tgaaagtgct ttcgttccat gaataatttc
    29701 aatatcttcc ttaaaatgtt ttattaaaaa attactagtt aaaggtgata gagaaagcac
    29761 tacatctccc tctaaatttt cttttattcc atcaagtata ttttgtgttt ctatgattat
    29821 ttcgtctcca aaaaagtttg ttaattcttc tttgtagtgg tcactattca atttatcatg
    29881 tgttataagg attaacttct ttttatccat tttatttctc ctaacaaaat agtatttatt
    29941 tttaaagtat ttaaagtata aggcaagtta tattatacaa caaatagtag tataaattta
    30001 tatatttgat taaataatag gtttttttag gattttatcc tataaaaacc tattttaaaa
    30061 ttatttttgc aagataagga aaatagcttt ttatattgta atgtatattt taaataatta
    30121 ataaaaaaat attatatttt taaacttgaa aagtaagtaa ttataagcta tttaatcact
    30181 ggaataaatt tacaataaaa aaataaatac aaaggcttta tcattaaggt attggcataa
    30241 gttttgctta ttaaacaagt atactaataa aattcattta aacaggaggg agaatttata
    30301 tgagtaaatt agaatcaaca acagaaaaag ttgaggtaaa atggtatggg tatgtagcat
    30361 taatattggg agcattattt ttttcaggaa tatttaaaga tgcaccagga ccattaaaag
    30421 tattggattt taacaatgta ttaggttctt ttggaacatt gggaacaatt aatgatggtg
    30481 taggtacatt agctgcaaac tttagaggtg atggaggtac tggccctcga gatggatggc
    30541 tatatgcatt gacattaata ccatcagtta tgtttgcact tggagtagtt agagttatag
    30601 accacttaga tggaatgaag gcagctcaaa agcttcttag tccactatta aagccattat
    30661 tagggttacc tggatttgca ggactaactt tgatagctag tttacagtct acagatgcag
    30721 ctgcatctat gactaaagaa cttaaagatg atgggtatat agatgaaaaa caaaaagctg
    30781 tattttgtgc atttcaattt tcaggtgcgt ctgcaattac gaatttcttt gcttctggag
    30841 cagcactatt tccatttata ggagatgtac caatatttat accacttgct ttaatattaa
    30901 ttatgaagtt tgttggggcg aacttactta gattatattt aaataaattt gacaaggggg
    30961 aagcttaaca tgagtgaggt agcaaaaaaa gaagtaaaag ttaaaaaagg aaatgtgata
    31021 gatgcgttta ttggaggagc tagaaatgga ttccaaataa gtacaaattc aatggctcca
    31081 aatgtcatct tcggttttgc tataatttct gtgttcaatt taacaggtct tttggatgta
    31141 atagggacaa tatttacacc tgtaatgagt atctttggac ttccaggtgt tgcagcaaca
    31201 gctataatga caatatttat atcaatggga ggagcatctg gagtaatcgc aggtttattt
    31261 acagcaggtc aaataagtca agcacatgtt gcaattctat tgccaatgtt attgctttca
    31321 ggagcgcaga tacaatttat ggggagactt ttaggaacag ctgagttaaa aactaaatat
    31381 tatccacata tgtttgttat agcaacttta aatggttgta ttgcaatgct tataatgaat
    31441 tatttcgtag tataggtaat tataataaag atttaatata aatggaaagt ttaaatttta
    31501 aggaggagct agattatgga aactaacaaa gactatattg agtatgtaca taaagtgtat
    31561 gattatctac acactatacc agaaaaagga tttgaagaat ataagacatc agagtttgtt
    31621 ttaaaagagc ttgaaaaaat ggggtttgaa aatattaata aaggaattgc aggaactggt
    31681 attatagtaa ctatagattc taaaaaagaa ggaccagtat ttgctataag agcagatatg
    31741 gatgcattgg aatttatcat agatggagaa aagaaaatga tacatgcttg tggtcatgat
    31801 ggtcatactt ctatgctttt aacagctgca aagttaataa aagagagaaa tttagtaaaa
    31861 agaggtaagt taaaaatact ttttcaacca ggtgaagaaa aattatatgg agcattaaga
    31921 gtaattgatt ctggtttgtt ggatgatgta gaagaaatgg tagggatgca tttaagacct
    31981 ggacaagatt gtaggttggg aaaggcgata cctgcaatgt accattgtgc tagctgtata
    32041 atggaattta cgattaaagg tatcacttgt catggttcta aaccacattt aggagtaaat
    32101 gcagtagatg ctgtctgttt agcagtgaat gcaataaatg caataagagt aaatccagct
    32161 ataccaaatt ctataaaagt aacaaatata tcagttaagg gagaaactta taataatata
    32221 ccagatgaag catttatggc tttagatata agggcagaaa gtaatgatat aatagaagaa
    32281 ttaaaagaaa aagcaataca tgctgtaaaa actgctgtaa gttctataaa tgcagaagct
    32341 gtactaattt ccaaagatgg agtaccagca gcagaatttg atgaagaact tgtaaacttg
    32401 gctgaagaaa ctataaaaga tgtattggga gctgatgcat ctataggtat atttaaaaat
    32461 tctggtggag aagatttcca ttattataca caaaaactaa aatgtaaaac tacatatatt
    32521 ggattaggag ctgatgctac accaggattt cataatccaa atgtaacatt tgatacgaaa
    32581 gctttagaat atggtgtaga tatatggtgt agattggttg aaaagagatt gggataacat
    32641 ccaaactaat aattctacat ttaaaattat aattatagaa gttatagaaa aagattgctt
    32701 atgttaatta gaaaataatt aatatgagca atcttatttt gatataatga aactgatttt
    32761 ggaatattga aaaaatatga tggaaaagta attatatttt aaatctattg gacaaaaaag
    32821 tgatattatt ataatattaa gaattgtaaa ataataccaa agtgcatcta gtaatagact
    32881 taacaattat aaaaatttta ttcttaggag ggaaaaaatg agtaagtata attttgacag
    32941 agtaatagat agagtaggaa cagattgtgt aaaatgggat tttagaacta attgttcaac
    33001 aaaagcacaa aaagatggtt tgcctttttg gattgctgat atggattttg aatgtgcaga
    33061 accaataata gaagcattac gtaaaaaagt tgaacataaa atatttggat atagttcaaa
    33121 tgatagtgat aaatacttta atgcagtttg tgattggtat aaaaggagat ttaactggga
    33181 aataaataga aaagatatta tttttagtcc tggtgttgta cctgctgttg ctattttagt
    33241 aagaatatta actaattcta atgaaggtgt aatagtccaa aaaccagtgt attacccatt
    33301 tgaagctaag ataaagagca ataataggga tgttgtaaac aatcctctga tatatgagaa
    33361 tggtacttat aggatggatt atgatgattt agaagaaaaa gctaagtgta gcaacaataa
    33421 agtactgata ctttgtagtc ctcacaaccc tgttggaaga gtttggagag aagatgaatt
    33481 aaaaaaggtt gtagaaatat gtaaaaaata tgacctatgg ataatagctg atgagataca
    33541 ttctgattta attagaaaag gatttaaaca tactccttta cagtcattat gcccagagta
    33601 caaggataaa atagttacat gtatagctcc aagtaaaaca tttaatctgg caggaatgca
    33661 gttgtctaat ataatagtga ataatgatga actaaaaaag aaatatcaag aagaggttac
    33721 agctgttgga gttgcaactt caccaaatcc ctttgctatt gtagctacaa tagcagcata
    33781 taatgaaagt gaagactggc ttaatgaatt aaatgattac ttagataata atatacaatt
    33841 tattgatgaa tacttaaaag aaaacctacc aaaagtaaaa cttgtttatc cagaaggaac
    33901 atatctagca tggttagatt ttactgctta tggattaaat gaagtagaac ttgaagattt
    33961 aatgtttaaa aaagctaatg tattatttga tgaaggttat atatttggaa aagaaggaat
    34021 aggatttgaa agaataaatg tagcttgtcc acagtcttta ttaaaagaat gtatggacag
    34081 attaaagact atatttgaaa atttataaag tataggtaaa aatttataaa gtgtttaaaa
    34141 ataaaaaaat aataaacttg acaaatttta actaatcact tatcatacta ttatgaataa
    34201 atagaaaaca taagagagct aaattttatt gaattaaact cttaaagact ttgaaaggaa
    34261 gagtagttat agaatgtaat taaagcgagt tggtgatggt gtgagaccaa tatgaagtct
    34321 ataatgaaga acatcctgga gttgctaacc gaaattttaa aagagtaggc ttagtcggaa
    34381 ccaaaccgtt atcatattgg ggtgtatcga gtaatatctg tacattgtga gctgggtttg
    34441 aatttatttc aaactaatca gggtggtacc gcggaaaagc aacctttcgt cccttttata
    34501 tagggatgaa gggttttttt aatggaaaaa tatataaata tagggagtga atgatatgag
    34561 cacaataata ccaaaggatt ataaaagtag tttgaacgta attgatacac aaatagctat
    34621 aaaaaaatta aaagattttt ttgaaatgag actaagtaat gaattaaatc ttataagagt
    34681 ttcttctccg ttatttgtat tgccagaaac aggtgcaaat gataatttaa atggagaaaa
    34741 ggctgtaagc tttgatatac catttatgaa taaaaatgca gaaattgttc aatcacttgc
    34801 aaaatggaaa agattagccc ttaaaaaata tgggtttgaa gttggtagtg gtttatatac
    34861 agatatgaat gcaataagaa aaaatgaaga attagacaat atacattctc tttatgtaga
    34921 ccaatgggat tgggaattgg ttatagataa aagtagtaga aatgaaaaga ctctaaaaga
    34981 tgttgtaaaa agattgtatg gagtatttaa agatactgaa atttttgtat gtagtatgta
    35041 tgaaggtata aaagaaatat taccagaaga aataactttt ataacatcac aagagttaga
    35101 agatatgtat ccagaattat caccaaagga aagagaagat aaaattgtaa aagagaagaa
    35161 agcagtattt ataactcaaa taggaaaaac attaatatca ggagaaaaac atgatggaag
    35221 aagccctgat tatgatgatt gggaattgaa tggggatata ttattttaca atcctgtttt
    35281 agattcagca ttagaattat cttcaatggg aattagagtt gatgaagaat ctcttgatag
    35341 acaattgaaa cttgctggat gtgaagagag aaaagagttt gactatcata agatgctttt
    35401 aaatggcgaa cttccgtata caattggtgg aggaattggt cagtcaagaa tatgtatgta
    35461 tttcttacaa aaagctcata taggagaagt acaagttgga gtatggccac aggatatgat
    35521 tcaaaattgt agtagtgcag gaattgaatt attataattt aaatataaac taattgataa
    35581 aatttatatc taatatgttc atcaaattaa ttatatcggt tataatgtag aataacctat
    35641 aattataaga ggtgataaat atggagtttt taaaaataat cattaatata gttttagata
    35701 ttttaaaaaa aattttggtc agatttaaaa atgctaaatt tggtttggtt tttgtatttg
    35761 atttacttaa actacctgat tttatgacag ataaaagaat caatatagtt gataaaataa
    35821 aggtaatttc tgtattaatt tttactatat cctactttgt atctggggtt gatataattc
    35881 cagagatgat tgcaggggca tttggtttta tagatgatgc tatagtttta atttggagta
    35941 taggtatagt gaatgaagaa attaataagt atagagttat cgcaaaaaaa gataaacatt
    36001 caaatataat tgaaaatgta gaattttcta taaaagatga agaagaataa caatttatat
    36061 atgttattct tttttttatt aacaaaaaat ggttaaattg ttgacggaga ggtaaaactc
    36121 tattatcata ataagtggat atccaatatt taactaagta ttcaatgtgc aagaatgctt
    36181 aatttaaaaa agttatggag ggtaaatatt atgaagaaaa aaataggttt agtgcccaaa
    36241 ctaatcatcg gtatcatagt cggtatttta atcggaagtt atgcaccaga aataatagta
    36301 caaatattag taacagttag tactttattc tcagcattcc taaaatttgt tataccattt
    36361 ataattatag gttttgtaac agcaggtata gctgatttag caacaggtgc aggaaagtta
    36421 ttggggataa ctacgggaat agcatatggt tctaccttaa tagcaggatt attatcattt
    36481 gcagtatcta cattaatctt cccaaatttt attgatgcaa gtgttgcaag tcaaattgga
    36541 gacccagagg caggaatgtt agctccaata ttcacaattc cattagagcc tatggtagat
    36601 gtaacagctg caatcgtatt tgcatttgta atgggacttg gaatatcagc tttaagaaat
    36661 catggaaaag gagagacttt atttaatttc ttccaagaat ttcaaggaat cgtaacgaaa
    36721 acgttgtcaa cagtgattat acctttatta cctttataca tagcaggaac ttttgcaaat
    36781 ataactatag caggggaagt atggacaata ttaggggtat tctggaaagt atacttagta
    36841 gtaatacctt tacattttgt atatatggca tgtcaattca cagcagcagg tgtattttca
    36901 ggaaaaaatc cagtaagaat gttaaaaaat caagtacctg gatatttaac agctatagga
    36961 actcaatctt cagcagcaac tataccagtt aatgttggtt gtgcagaaaa aaatggagta
    37021 agtaagcaaa taagagaatt tgttgtacct ctttgtgcaa caatacattt atcaggtagt
    37081 atgatatcaa taacaggatt tacaactgca gttttaatga tgaatggtat gccacatgga
    37141 ataggtgtat tattccctta tattgcaatg ttaggtatag caatggttgc agcaccagga
    37201 gcaccaggtg gggctataat gagtgcactt cctttcctac caatggttgg aataccatca
    37261 gatggtgggc ttgcaagttt aatgatagct ttatacttaa ctcaagacag ttttggtaca
    37321 gcatgtaatg tatcaggaga taatgcaata gcagtagtag tagataaaat aaatgatgga
    37381 atgagtaaaa aaggaaataa agaagagcaa agtgcttagt tttttaataa tcaaaaatga
    37441 gttatctcaa atagagatag ctcatttttt atggtataaa aaattataaa ataaagtgat
    37501 ttttttattt aaaaattgct ttaagagatg atattaataa tttattttca ttaggtttta
    37561 atatacatac tctaaagaaa tactcatcta gaccttcaaa tgaacaacaa tctcttatta
    37621 ttattttttg tggaagcaat tgttctcgaa gagatttagc agtcaattcc tttgtcttga
    37681 ttttacacaa tatgaaattg cctttagtat tgtatatatc taagcttttt atattcttaa
    37741 gctctttaag caggtaatct ctttcagtgt tcattaagga aatagtattt gatataaaat
    37801 ctaaatcact aaacatgatt tcacccattt tagaagctat tatgtttata ttccataaat
    37861 ctagattttt atttatttca tttttgacat tagtgttaga tataagacca tatccaagcc
    37921 ttattccagg cgttgaaaaa aattttgatg tacctcttat aacgaataaa ttagaataat
    37981 catcaactaa ttgagtacaa gagtatgtat ctgtatcagt aaactctaca taagtctcat
    38041 caatcattaa aaatgagtct gtatttttta aaatttctct cacttctact ttagtaaatg
    38101 caaatccagt tggattacta ggattacaga ttactaccaa atcataatct ttagcattga
    38161 tagtttttat aagattttct aaatttatat gaaaattatc ttcttctttt gcaaagtatt
    38221 tttctataga acaattaatt ttagataact ctttttcata ctctgaatag gctggagaga
    38281 gtaaaagagc ctgtttaggg ttaattgtat gtataaatga tgaaattagt tctgtagctc
    38341 cactgccaag tactatatta tctatagaac atttgcagta attggatata gaagttttta
    38401 agtctatgta atcagggtca ggatacatag ataccatatc tatattgttt acaatgtatt
    38461 gtttggctaa acttgatgta ccaaaaggat ttatatttga gctaaaatcc ataaattctt
    38521 cctttgaaaa gccatactta ctagataaac tatataaatt agctccatgg tttgtgctca
    38581 taaaagtacc tccaaaaata aaattatata atcgataaaa ataactgatt aatatatgta
    38641 catatagatt ataatacaaa ggaatcgtta ttccaaattt ttaatggaaa aagcaaaaaa
    38701 gtatggataa gctgttaatt taggtttaaa aatgatgaaa aagattttaa ttgatatttt
    38761 ggtatgctat aatatataag ttaatagaag gaaagcggga ggatacaaaa tgtacaaagt
    38821 tacaggaaaa atgttgacag aagaacaaat aaaagaaaaa gtttatgaat taggaaaaaa
    38881 gatagaagaa gactttaaag gcgaagattt actagtggta ggtatactta aaggagctag
    38941 tgtatttgtt tcagatttaa taagatgtat agatttggat gtaaatatag attttatgag
    39001 tgttacaagt tatggaaact caacagagtc ttctggaaca gttaaaatat taaaagattt
    39061 agatgtagat attgaaggaa agaatgtgtt gattgtagag gatataatag attctggttt
    39121 aacattaagt aatctagttg cagctttaaa aactagaaat ccaaaatctt taaaactatg
    39181 tactctactt gacaaacctc agagaagaaa agctaatata cctgtagact atgttggatt
    39241 tgttatagaa gacaaattta ttgttggtta tggaatagac tatgctgaaa agtatagaaa
    39301 tttaccttat ataggtatag ttgaggatgt agaatagatt taaatgtgaa tcaaaagcac
    39361 taatttctaa gggagttagt gctttttagt taattatata aaattttagt aaaggagaca
    39421 tctatatgga tattcagtta aatatattat tatttttcca aaatttaaga aatccaattt
    39481 tgaactttat atttcttgtc tttacaataa gcacagaagc accgttatta atattaatta
    39541 caacaattat atactggtgt ataaataaaa aatgtggaca gaaaatactg tttgctataa
    39601 ttggaaattt tgttgtaaat ttaggcatca aagagtttgt aaaagctccc agaccaatag
    39661 gaataaaagg tcttgaatca ttgagagttt ctactgctgg tggttattct tttccaagtg
    39721 ctcatactca aactgcaaca acattttggg ttagtattat gactatattt aaaaagagat
    39781 atcttcattt aataggtgca gttatggttt taggagtagg attgtctagg ctgtatttag
    39841 ctgttcattg gccaatagat gtgatagcgg gttggatatt aggaatattt tttacagttg
    39901 tatttgtaaa aatatttgac tatattgatg ataataaaaa ttatatttta cttgtagttt
    39961 tacttatacc atttataata gtggctatat ttctaaatag ccctgaatat tttgaaaaat
    40021 ttggtataat agtaggattt gtatttggat atatggttga ggatagattt gttaaattta
    40081 atacagataa taataacaaa aaaataaatt ttagtaataa aaataagggg agtaaaaata
    40141 taattttttc aagaatatgt aggtttttgg ttgggatagt aacaatagga atgttatata
    40201 ttggcattaa gttgtttatt tcaatgttaa tagtcacttt aaatataagt gactctacta
    40261 tgagtataat ttttatgaat tttattaaga atacagtagt tgttttttat ggaatagcag
    40321 gagctccagc attatttaaa cttttaaaat taaattgatt ttaaggtata gagtcaatag
    40381 tttaaattaa aaaaattaag ggtagaaaag agtgattatt tgaagaaggt agtaataata
    40441 ggtggtggac cagcagggat gatagccgca tcaactgcat gtgagaaagg ctatgatgta
    40501 acattaattg agaaaaatca taaattagga aaaaaacttg caataacagg aaaaggtaga
    40561 tgtaatatta ctaacgcttg tgaaatagag gaattaatag aaaatgtacc tacaaatgga
    40621 aaatttcttt atagtgcttt ttatactttt acaaatgatg atgtaataag tatgtttaat
    40681 aatcttggag taaagactaa aacagaaaga ggaaaaaggg tttttccaga gagtgataaa
    40741 gcatttgata ttgtaaatgc tcttgaaaga caacttaaaa gtaagaaagt aaatatatta
    40801 ttaaattcga aagtagaaaa aataatatct aaaaataata aaattgaaaa agtaatttta
    40861 aacgataaaa aagaaattaa gtgtgattca gttgtagtag caactggtgg attaagttat
    40921 ccacttactg gttctactgg tgatggatat aaatttgcaa tttcacaggg gcacacaatt
    40981 atagatacaa aaccatcttt aattggtata gaagtacaag aaagttttac aaaagattta
    41041 gaaaaattat cattgagaaa tgttgaaata agggtgttta atagcaaaca aaagaaagtt
    41101 tatagtgatt ttggagaact tgaatttact aaatttggtt tagatggacc tataatcaag
    41161 tctgcaagtt gtagaatgaa agatacaagg aaagaaaatt acactatatt attagattta
    41221 aaacctgcat tagatgagga aaaattggat aaaagagttc aaaaagattt tcagaagtat
    41281 acaaataaaa aatttgaaaa agcattagat gatttacttc caaaaaaact aatacctata
    41341 ataataaact taagtgaaat taatccaaat acggttgttc accaaatttc tagagagcag
    41401 agaaaaaact tagtccattt attaaaaaat ttaaagttta cagtaaagag atacagacct
    41461 attgaagaag ctataataac ttctggtggt gtaaaagtaa acgaaataaa ttcaagtaca
    41521 atggaatcaa aattagtaga aggtttattt tttgctggag aagtaataga tatagatgca
    41581 tatacaggtg gattcaattt gcaaatagct ttttctactg gatatttggc aggttttaat
    41641 tgctaaaaat tacctgaatt aaaaatgttt aaaatcacat aatattatca gcaacacaaa
    41701 ataaattaaa cagaaggaag gtaatcaaca tggcaagtaa caataacaac aacagaacag
    41761 tagtaccagg agcaaaagag gctttaaacc aaatgaaatt agaaatagct aatgaacttg
    41821 gtatgagtaa ttatcaacaa gttgataaag gaaaccttac tgcaagagaa aatggttatg
    41881 taggtggata catgactaaa aaattagttg aaatggctga acaacaaatg gctggaaaaa
    41941 gcaacagata gttataaata attatttata actattggct attagtttag ctagagctat
    42001 ctcaaatata gaaagtaatt tctaaattga gatagctttt ttttattaaa ttattaaata
    42061 gatatatttt tatgtaataa attttatgta tttggataaa ataatacaaa tgaatatgtt
    42121 acataaggag tgatgtaaaa tgagtagtgt aaattttgag gatttaaaaa acaaatttat
    42181 taatagtgac ttagatgaaa aaataagaat atatacaaca acagaaggtt tatcagtaga
    42241 acaatttaaa gagctactaa aatattatcc aatacaacat ttatctaaac tagaaaaagc
    42301 acttggatag cagtatttaa tccaaaatta aaaaggcaat ttatttaata ttaaaaatat
    42361 tttttattaa ataaattgcc tttttataat aggtttaaat tattatgctt ttgatatata
    42421 attatagatt ctctcatttc caagttcaat agacccagta ttaataagag taactattcc
    42481 ttctatatct ctagcagtta agtatttata tggaattaat aaattataac cagtattact
    42541 tagtaagttt tttaattggg ttatttgaga gatattgaaa cattttgcag ttttagtaga
    42601 tttttttctt aagttagata aattttcatt ttgaatattt attaaagttt ctatatagtt
    42661 tctataagat atcttaaagt ttgtctcatt gactattttt tcattaagta tactactgat
    42721 aaaatcttga gacaatatat tatctgcaaa tttatctgct gttaattttc cagatgttat
    42781 gcctttttga tattttctaa gaattttttt agtatagcag tatattttat ttctcgtttc
    42841 taaatcgagt tgttctattt gcacaaaacc acttccttct aattataaaa atatttatta
    42901 aaaatctata cttaactaat aaagcttcaa taacttattt acaataaata ctaaatcata
    42961 aaatatttgt tattttttat tattaccaag tataaaaaat attataattg taaaacttac
    43021 aaatatatgt aaaatattta ggagtgatga aaatgttaaa tgggataata aagctttttt
    43081 attctgaaat tgtaaaaaca aagattaata acttagattc aagtggatat tctttaagag
    43141 atgaatgtaa agaaatcaga aatataactc taaagataga tagtgtattt tttaagcttt
    43201 taaagttagc ttttggttca atattgctta tggtagcttt taatttaaac atggttttag
    43261 gtataggagt gtttttagtt ggtgtagttt atatactata taaaagaaat atggaagaac
    43321 aagtaaaaga gcatataaat aatgtgaaaa ataatatcga catctctaaa ataactttta
    43381 tggatgaaaa agggagaaca ggtctaaatg cattaattac attacttctt ataggattat
    43441 tgacaggatt taactggata ttagttgcta gttttgtcgt tgtttttgtt tttactataa
    43501 agaatgtatg ttaaaatact aataaatagt ttaatatata gggggagaaa ttgagtatga
    43561 ctaatggcag ttataaaatg aagaatttag tggaaatatc cgctatggtg actgaatcta
    43621 cagatttttt taatataaaa gatgacataa tagaaaaaat gttagaagtt gttcacccta
    43681 caaaggcatg tgtgaatcta ttttataaaa atgattctaa atatgcctac ttagtatgtt
    43741 cgcaaacctt agaatatgta cctcaaattt ttccaataaa tagtcttaaa ggtgcaaaaa
    43801 ttgattttga cacatatcca gagtatatac atgaggctgt aaatgaaaaa aaaataatat
    43861 atgtggaaaa tgtatttgaa gattctagag cagaaggtga acgagattta gcaaaagctg
    43921 aaggttatat tgggagaata gtttttcctt ttataataaa taacgtagtt gttggattta
    43981 tgacttgttt tttaaaagag gatgattata taacagaaca agatatagat tttatatcat
    44041 ctgttgcatc actcttaagt ttatcaatag aaataactaa taaaaataat aatgtacaaa
    44101 ttttaattga taaactaaga ggctcaataa gtgccataaa tgaagctact aaaaaactat
    44161 accttaataa gagtattgat ggatttttgg aaaatttaag taaacaagcg tgtaatatta
    44221 ctaatagtaa agaagcttta ataattataa atagtcatca taataaggat gctatagtta
    44281 gttgttataa tgttgagcaa aaaaagaaaa caaatttata tcctatgatt gatatgtttt
    44341 taaagaaaga gtcattgggg gggtatttaa ataatttaaa accatgctca aaaaagggaa
    44401 taaatttgga aagttatata tattacaaac ttcaggataa aaatgagact ataggatgta
    44461 tagtttgtgc aaatagcaaa aactatacta gtgatgattt aaatattctt agtatattgt
    44521 ccaaacaagt ttctgttggt atgcaattat atgaacataa tgaaaaggaa gtaaaacaca
    44581 aagttcttga aaacgagttg aacatattaa ataaacaaca acagcttatt atggataaag
    44641 gtaaaatgga ttgtaatgat gagaaagaac tttattttta ccataaacca gcaagggtag
    44701 taggtggaga tttttattat gctacaaaag tggatgatga acatatagtt tatattgttg
    44761 ctgatgtaat gggacatgga atggtatcaa attatgttgt tgcaatgata aaaggtgctt
    44821 ttaaagtatt atgcaatcaa tacaatacac caagagaaat aatgacaaat ttaaatagga
    44881 tgttatatga tgaatttgac aagatgggag tatttacaac ttgtttgata ggtattatag
    44941 atactaaaga aaatatgatt actgtgtcta atgcaggtca ctatagtcct gtagttgtaa
    45001 agaaagatgg cacaatagaa aataatttaa attgtaaaaa gggcatacct attggaataa
    45061 tggaagatgc tacttatgaa aataatactc tttcaatgga agattatgca atggtatgta
    45121 tgtacactga tggaatttta gagataaaaa attcatcaaa agaagagtat ggtataaaca
    45181 gattagaaaa ctttctaaaa gaaaatttta gattaaatca acagttaata gtagaaaatc
    45241 taaaattgga tttaaagaac ttctcatcaa aagataatta tgatgatgat attttaatag
    45301 ttatgttaaa ggataggtag attgattatg gattcaaacg ataaaaaagg acttaaaagt
    45361 ccagagatta taataataaa tggaagtcca agaattaata aaaattgcag ttttatagca
    45421 aatgaagtaa aagctatgct agaagagtgt ggattaagtt gtaaaatatt taatatctac
    45481 aatatggata ttgaatattg cacagcatgt ggattttgtg aaaaaacagg gtattgcaag
    45541 tttaatgatg atatgaagcc attatataaa atgtttgatg attcaaaagg aactatagta
    45601 ataagtcctg tacattttga ttcaatatca gctaaattaa agactgttgt tgatagaact
    45661 caagctatat atgcaagtaa atatgtatta aataaacctt caattgatag aagtaagaaa
    45721 cggataggaa tgtatattgc agtgggaggg agtaaatcat atgattcaca gtttaaaggt
    45781 ggacagattg ttatggattt tttctttaag agtataaata ctaaactttt acacaatata
    45841 tatttaaaca atacagatga tgtatcttat atagataatc aagaatttaa agatataata
    45901 tataaaaatt taaagatata tattgattca atataatttg attttgtagg taatattatg
    45961 tataattgta ttgcaataat ttaaataatt aaaaggaggg aatttcaatg aaattaccaa
    46021 tagcattatc taataaacat gttcatttga gtcaagctga tatagacgta ttatttggag
    46081 caggtcatga gttaactaaa tttaaaccat tatctcaacc agggcaatat gcctgtgaag
    46141 aaaaagtgga tttagtagga ccaaaaggaa ctttaaaagg agttagagta ctaggaccag
    46201 ctagagctca tactcaagtt gaaatatctt tagcagatgg tttcccatta ggagtaaaag
    46261 caccaataaa agaatctggt gatatagctg gaactccagg tgttaaatta gtaggacctg
    46321 ctggagaagt tgaaatgaaa gaaggagtta tagttgcttc tagacatata catatgagca
    46381 atgaagatgc tgctaaattt ggtgtaactg ataagcaaat agtaaaagtt aaaacatctg
    46441 gaccaagagc attagtattt gaaaatgtat tagtaagagc tagtgacagc tttaatctag
    46501 aaatgcatgt tgatatggaa gagggaaatg cagcaggcgt taaaaatgga gatttagtag
    46561 aattaatagt tgattaatat tataaataga ctttatgcta gtagatattt tatttgctag
    46621 catattttta aatgtaataa atttctatag gataaattta atcaattaga ttaatttata
    46681 aaataaaggg gtattataaa aaatgtaata aaaacttaca aaaatatgat gtaatatggt
    46741 aaaattatat atataaaaat ttacatgtaa taaggataag cattttactt tttatactaa
    46801 tatgaacaaa tagataaaaa agtttgaaaa atctaactta atttattata tattgtatac
    46861 aaaattatga aaaaaactta acatatttaa ttttaaaaaa aatctactta aatatgtaat
    46921 taatttacaa ttttcaaagg aattttatct aatctgtagt attatattag aagatagagt
    46981 atttgcgcga ctatatgtgt gtttatagtt ttgttgtgta aattatatgt aaatataaaa
    47041 aaatagactt gttataaaca agtacaattg tagctatcaa ggaggataca tattatggct
    47101 aagtttatga aaacacttga tggaaataca gctgcagctc atgttgccta tgcgtttaca
    47161 gatgtagcag ctatatatcc aatcacacca tcttcaacta tggctgaagt agttgatgag
    47221 tgggcatcac aaggaagaaa aaatatattt ggacaaacag ttaatgttgt tgaaatgcag
    47281 tcagaagcag gtgcatcagg aacattccac ggttctttac aaggaggagc tttaacttct
    47341 acttttacag catctcaagg tttattatta atgataccta acatgtataa agttgcagga
    47401 gagttgttac caggagtatt ccatgtaagt gctcgtgctt tagcatctca agctttatca
    47461 atatttgggg atcaccaaga cgttatggct gctagacaaa ctggatgtgt attattagct
    47521 tctggttcag ttcaagaagt agctgatata gcacctgttg cacatttagc tgcaatagaa
    47581 ggtagattac catttataca tttctttgat ggattcagaa cttcacatga aatccaaaaa
    47641 gttgaattac tagaaaatga agattatgca agtttattaa actttgaagc agttcaagca
    47701 tttagagata atgctttatc tccaaatcat ccagttgctc gtggtactgc tcaaaaccca
    47761 gatatatatt tccaaactag agaagcttct aataaatact atcaaaatat agtaggtata
    47821 gttgaaaaat acatggaaaa aatgagtaat ttaacaggta gaaaacatag tttatttgat
    47881 tactatggag cagaagatgc taaatacgta ttaatagcta tgggttcagt aacagaaaca
    47941 atagaagaaa ctatagatta cttaaatgct aagggagaaa aatatggttt agttaaagtt
    48001 catttatata gaccattctc aatgaaacat ttcttagatg ctatgccatc tactgttgaa
    48061 agaatatgtg tacttgatag aactaaagag ccaggttcaa ctggtgaacc attatactta
    48121 gatgtacgtg atgtattcta tggaaaagaa aatgctccta tgataatagg tggaagatac
    48181 ggattaggtt caaaagatac tactccttca gatataaaaa ctgtttttga taacttagtt
    48241 tcagaacaac ctaaaaatgg atttacagta ggtatagttg atgatgtaac taatacttct
    48301 ttaactccat ctgagccaat aaaaatagct tctaaaggaa ctataagatg taagttctgg
    48361 ggattaggtt ctgacggtac tgttggagct aataaacaag ctatcaaaat aatcggtgac
    48421 catactgaaa aatatgctca agcttacttt gattatgact ctaaaaaatc tggtggtata
    48481 actatgtctc acttaagatt tggtgatact ccaataagag ctacttattt aatagatgaa
    48541 gctgattata ttgcctgtca taaacaatca tatgtttatc aatatgattt attaaaaggt
    48601 cttaaaaaag gtggtacatt tgtacttaac actatatggg accaagcagg acttgaagaa
    48661 catttaccag ctcatatgaa acaatatata gctaaaaatg atataaaatt ctatacagtt
    48721 aacgctgtta aactaggaca agaaataggt cttggaaaca gaataaacat gataatgcaa
    48781 tctgcattct ttaaattagc tgaaataata ccagaagaag atgctgttaa atacttaaaa
    48841 gattctatag ttaaagctta tggtaaaaaa ggtgaaaaaa tagttaacat gaactatgct
    48901 gctgttgatg caggaataaa tgctttagtt aaagttgaag ttccagcttc ttgggaaaat
    48961 gctgttgatg cagataaagg agaagttaaa gaaccagaat ttataaaaaa tatactaaga
    49021 ccaatgactg cacaagaagg aaacaactta ccagtaagta cattcaatgg tatagaagat
    49081 ggaacattcc cttgtggtac tgcagcttat gaaaaacgtg gtatagctgt tgatgttcct
    49141 gaatggataa tagataactg tattcaatgt aaccaatgtt cttttatatg tcctcattca
    49201 tgtataagac cagtattagt tactgaagaa gaattagcta atgctccaga aggatttgaa
    49261 gctaaaaaag cattaggtaa aggattagaa ggattaaaat atagaatgca acttagtcca
    49321 cttgactgta caggatgtgg aaactgtgct gacatatgtc cagctaaaga aaaagcttta
    49381 gttatgaagc caatagatac tcaacttgat acagagttag ataattgggc atttgcagta
    49441 aatcctgatg aggtagctcc aaaaggtgat gttatgcctg caaacactgt taaaggaagt
    49501 caatttagac aaccattaat ggagttttca ggagcatgtg ctggatgtgg agaaactgca
    49561 tacattaaag tagttacaca attatatgga gatagaatga tgatagctaa tgctactgga
    49621 tgttcttcta tatggggagc ttctgcacca tcaattcctt atacttgtaa ccatgaaggt
    49681 aaaggtccat cttgggcaaa ctctttattc gaggataatg ctgaatatgg atttggtatg
    49741 tacacagctg ttaagcaaat aagaaataaa atagtagatg ctatgacaga gttagtttct
    49801 atggatatct gtgaagatgc taaagcggta tttacagagt ggttagattc tagaaatgat
    49861 ggagaagctt ctaaagtagc aagtgctaag gttgttgaat tattagaaaa accagcttgt
    49921 gattgtacag atgaaaaagc taaagagtta gtaaaagcta taaaagatag aaaagattat
    49981 ctagttaaga gatctcaatg gatactaggt ggagacggtt gggcatatga tatcggttac
    50041 ggtggattag accatgttct tgcatctggt gaagatgtaa acgtacttgt atttgataca
    50101 gaagtatatt caaatacagg aggtcaagct tctaaagcta ctccagctgc tgctatggct
    50161 aagtttgctg cttcaggtaa aaaatctaga aagaaagatt taggaatgat ggctatgaca
    50221 tatggaaacg tatatgtagc tcaagttgct atgggtgctg ataaaaacca atttatcaaa
    50281 gccgttatag aagctgaaaa acatgatggg ccatctttaa taatagctta tgctccatgt
    50341 ataaaccatg gattaaaaga aggtatggga agaactgtag ctaacgaagc acaagctgtt
    50401 gcttgcggat actggcattt atacagattc aatccagaag taaaagctga aggtaaaaac
    50461 ccattcactt tagattcaaa agaaccaact gcaagcttca aagatttcat acttgcacaa
    50521 gtaagatatt ctgctatagc taaacaattc ccagaggaag ctgatggatt atttgctaaa
    50581 gctgaagctg atgctaaaga aagatatgaa ggatacaaaa aattagctga ataatattaa
    50641 agtattataa tgcttatata gaattgataa aagagagtgt ctcaaagtga gctttttagt
    50701 tcatgaggca ctctttttgt atgaaatcaa atatatttta atcatttcaa caatgaaaaa
    50761 ggccttatct ctattttgag acagcctttt tttatgaaga tattaagatc ctgtttttac
    50821 ctattaaata tctttttaag ttttccattt tcatcttgcc aatacttttt atatattgct
    50881 ctacacacta aaattaagag aacaaataat atttatagta tgtatatttg gatttgataa
    50941 ttttaaaata gatacaaaag agtatctcat ttgtgttttt tatcacttag agataatctt
    51001 ttgatatgta tggaaaaaga ttattttatc ctacaaagat ttgtgtccaa taaattgaac
    51061 caccactttt ttgtgctact ccaacaccta ttttactgaa atttggattc attatatttt
    51121 ttctgtgacc ttcagaattc atccatgcat ttacaacttc tttaggagtt ttttgaccca
    51181 tagctatatt ttcacctgct gtcttatagc ttattccaaa ttttttcaac atgtcaaatg
    51241 gagaaccata agttggagaa ttgtgtgaaa aatagttgtt atcaatcata tcttgagatt
    51301 tttttgtagc aacatttgat atagaagaat caagagtaag aggatttaat ccagctttag
    51361 ctctttctat atttactaag tcaacaactt ctttttggta agctgaaaaa ctttcacttg
    51421 tagagcctga gttgttatta tcatcaggtt tgttagtaga gtctgaatta ttgttgtctt
    51481 caggtttatc agtagagcct gaattattgt tgtcttcagg tttattagac tcaggtttat
    51541 tattatcagg tttattagta gagcctgaat tattgttgtc ttcaggttta ttagactcag
    51601 gtttattgtt accaggctta ttagtagagt ctgaattatt gttgtcctca ggtttattag
    51661 tgttgttgca attcttgtca ttatgattct tatccttaca agagttatct ttatcaggct
    51721 taagttctgg ttttacagaa caatttggtt ttgcagaaaa cttgtattta gtattactat
    51781 atactaaact tttgttactt atatttacat tattttcaag tgatgaagca cttgcagtaa
    51841 cagcacttga agctgttgct aaagttaaca ctcctaaagc taatatagtt tttaattttg
    51901 ttggtatatt tcttctcatc attaaacacc tcttaatcta aaaattctaa aaatgttact
    51961 gatttgtaac ctttagtgta gggggttacc cgtgaatcta tactaacata agattaagac
    52021 tttttttact gtaaagatat gtaaaaaaga tatatatgga ataaataggt atatttcagt
    52081 gtgtttgaca atttgtatta aaagcctgta tagtatggaa ttacttagtt agagaaaata
    52141 atatttttat aataattcca taacgtaaat ttatagttat gataaatttt tttttatttg
    52201 gttaaattta ttcagtagat gctttcgtat tagcaacaaa ttataattat ttaaatcttt
    52261 aagaaataaa aagggtctgt ctcaaaatag agataaggcc ttttttattg tttaaatgat
    52321 aggcatatgt tatttcatat aaaaagagtg tctcattaag taaaaagttc actttgagac
    52381 accacctttc atattatgaa ttttaatttg ttttatatta atacattagt aatcctaatg
    52441 taattacaat aatttctgct attagtgaac caactgcaac tacaatgaaa gtttctttaa
    52501 atccagtttt atgtgttaac ttagataagc ttaagaatgt aagaaaaaca ccactttgtg
    52561 gaactatagt tagtatattt gaagctattg tagcaacacg gtgaattaat tctggattta
    52621 gaccagtact taaataataa tctgcaaagt ttggcattac tattcctaat gcaccagaag
    52681 aggaccctgt tattgctgac attgttgaag tcaaaacagt aagacttata agtggactac
    52741 ctggtattga cattataagt ttgctaaata catcaaaacc aggtgcagcc attattactg
    52801 ctccaaatgc aactgcagaa gatgtagcaa atataggacc tatagaacca ctagcaccta
    52861 tgctcaatgt ctgtatctta gatgatagaa atttatggaa taaaaaagca gataaaagaa
    52921 ttgcaactat taaagctatg taaattacat tttttttcat aaattctgaa ccaaaagtac
    52981 ttccagttat agctataatt acgagtgcta atagaggaaa aatacttgca aaaaatcctg
    53041 gtaattctct atctaaagat tcttcttcta attctgaagt ataagttgca taagtttcac
    53101 cttttctaat acttttgttt agagcatatt tcatatagac aagtccaaac gtagcacaac
    53161 ctatactacc tacaatactt ggtatagtag ctgcagtaag agacgtattt agatattgaa
    53221 taggtataac attttgaatg gctggtgttc caggaattat agtcatagta attgttgcaa
    53281 taccaagcca aagtggtatc tgaataaggt tccaagaaat atcaagtttt ttaaatagag
    53341 ttcttgcaag tggaatgacc gcaaacataa ctacaaataa gcttatacca ccatacgtta
    53401 atataaaact tactataaat atagcaacta aaactctata aggatgatta gagccaaatt
    53461 tatttaaaat aaaatcagct attgatacag tagctccact ttcttccata aatttagcaa
    53521 gtattgagcc taataagaat attgcaaaat aactcattat atagtttcca agtgcaccca
    53581 tataattgtt tttgtcagca cctagcattg atgttacaac atccatttta tttaaaataa
    53641 caactattaa agttgctatt ggagcagcta tagttatatg aatttcttta actgaaaaat
    53701 atataatagc tatgatacca ataattatac caattggtgc gataatactc ataaatatcc
    53761 ctccttagta gaaggacctg aagaatactt tcttcaagcc ctaaatataa taactattgt
    53821 gcagtatatc ctccatctag taagcaagct tgtcctgtaa tacccttagc attatcactt
    53881 gctaagaaca tagcatagtc ggcaatttct tgaacatcta ataggcgttt ttgtggtaca
    53941 agtgggtata aaacttcctc taagacattt tccaatggta tattacgagt ttttgaaagg
    54001 tcattgaact gacctctgac aagtggagta tctacatatc cagggcataa agcattaact
    54061 gttataccag aatcggcagc ttcaagagca gcaacttttg ttagtccaat aagtccatgt
    54121 tttgctgagt tataagcagc ctttccagca aatcctatta caccattgat tgaggccata
    54181 tttattatac gaccaaagcc ttgttttttc attataggaa atgctttttt agtagctata
    54241 aaaggtgctg tcagcattat ttttatcata aattcaaatt tatcagttgg gaaatcttct
    54301 atcatagaaa catgttgaag tccagcattg tttattaata tatctaatct gccatacttt
    54361 tcaacagttt tgtctatagc gtggttaatt tcttcttcct tagttacatc acactttaca
    54421 ctcatgcaat cataaccttt tttttgtaac tctgttatgg tattatttaa agcttcttga
    54481 tttatatcag agaacattac tttagcacca ttttttaaga acgattcagc tatttgttta
    54541 cctattccac ttgcagctcc tgttacgaat acaactttat ctttaaccat tttcatttcc
    54601 tccaatttta ttttattttt atattaatat tttaagcaat acaaatttat atgtaatacg
    54661 tctaagagat ttttattttc tagttttaat tattttaaac aacagatatt tttccattta
    54721 atgaatctga caatattaaa ggagcctcag tagcagaaat aacatcatct aatgtgaaag
    54781 ctggatttat ttctttaagt aaaattccat ctgatgttac ttccataact cccatttcag
    54841 taactatcaa atctacagca tttgttgcag taagtggaag agtacaatta tttaatattt
    54901 ttgcagaacc ttttgaagta tgttccattg ctacaataac ttttttagct ccagttacta
    54961 ggtccatagc tccacccata cctggaacca tcttacctgg aatcatatag tttgctatat
    55021 taccatattt gtcaacctga agtgcgccaa gaacagttat atcaacatga cctcctctga
    55081 ttattccaaa agaagtagca ctatcaaaga aacatcctcc aggaagtata gtaactggtt
    55141 gaccacctgc atttacaata gtttcatcac ttgaatttcc atcttcggct gaacctaaac
    55201 ctaaaaagcc attttcagat tgtaagataa cgtttacatt atccggaata taatttgcta
    55261 ctttggttgg tagacctatt ccaaggttta caacggctcc gtcttttaat tctttagata
    55321 ctctatttgc aatatattct tgcatttcta atttatccat tataaattac ctccttcaat
    55381 gatgtaattc acaaaaatac ctggtgtatt aacttcattt gggtcaatat caccaatttc
    55441 aacgatttca tctgcttcaa ctattgtaat tttggcagca gatgccatta aattattaaa
    55501 attgttcata gagcctttat aaactagatt acctgcttta tcgacctttg atgcaaatag
    55561 aagagcaaca tctgcataaa ttggtttttc aagaaggtat tctttgctat cgacaacaat
    55621 tttttgcttt ccctcctcaa caagagtacc aataccagtc ggtgtgagta tacctcctag
    55681 accataacca gctgcacgta tttgttcagc aagagttccc tgaggaacta actcaacatc
    55741 tgtttcattg ttattcattt gtcttccagt ttctttattt aatcctacat gagaagcaat
    55801 tatcttttta aattgcttat ttacaaccat tttgccaact cctttgtcaa taaagccagt
    55861 atcattgcaa attagtgtca aatcttttat atttttacta cataaataat caattaaatt
    55921 ttctggtgaa ccattggcca tgaatccacc aaccattatt gtatctccat cttttacatg
    55981 agatagagct tcatcaatgc taactatttt attcatattt cctcctatcg tgaaaccacc
    56041 attgatattc cttgaccacc accaatacaa agtgttgcaa gtccagtttc aactttacgt
    56101 ttttgcattt cataaattaa ggtaacaagt attctagctc cacttgctcc tattggatgt
    56161 cctaatgcta ttgcaccacc attaacattt aactttgatg aatctatttg aagttcattt
    56221 ttaacagcta atgcttgggc agcaaacgct tcatttgctt ctattaagtc tatatcattg
    56281 atgctaagtc cagctttttt cagtgctttt ctagttgcag ggattggacc agtacccatg
    56341 acttcaggtt caacaccagc tgaagcatag gattttattt tagcaagtgg tctaatacct
    56401 agttcgtctg ctttttgttg gctcattagt attaacatag ccgcaccatc attaatacct
    56461 gaggcatttc cagctgttac agtaccatct tttttgaatg caggtttaag tttagctaaa
    56521 ccttcaaatg tcatacctaa tttaggatat tcatctttat caatagtttc tatttttcct
    56581 cgacgtatta aaacatctac tggaacgatt tcttctttaa agcggttgtt ttttatagca
    56641 ttctcagcct tactttgact ttctaatgcc aatttatctt gcatttctct agtaaattca
    56701 aatttagttg caatattttc tgcagttatt cccatatgat actgattgaa agcatcaata
    56761 aggccatctg ttagcatact atctaccatg gttatgtcac ccattttact accaaagcga
    56821 gcagttggaa cgatataagg agcttggctc atattttcag taccacctgc aattaccaca
    56881 tcattttcac cagatgtgat tgattgggca gctagctgga cacttttaag ccctgaacca
    56941 cataatttat ttactgtgta gcttggaaca gaatttggta tacctgcatt tatagcaatt
    57001 tgtctagcaa cattctgtcc aagccctgtt tgaagaacat ttccaattat tacttcatct
    57061 atttcagata aattaagtcc tacacgtgat atcgcttctt taacagtgat agttccaagt
    57121 tgaacagctg aagtattttt aaatacacct ccaaaacttc ctataggtgt tctgactgct
    57181 gatacgatta ctacatcttt catatctaat agttaccttt cttgaatgat aattaaaaat
    57241 tttctgaata aagaaattag gaaacactat aataaagtac ttttttaata caagcttgtt
    57301 tttaagtatt tcaattactt ttattcctaa tgctttaggt tttcctgttt ctaattatag
    57361 attacggcga aaaaagcgtt ttgtctaagt ctaatttttt atatagtgta taagaaaaat
    57421 ttataggata aaaatttata gtagatttag aaaaatattt tgttaaaata ttaatgaaat
    57481 tatgttgatt ttcctataaa atatcattag aagaaaaaat ataatctaaa ttatactttt
    57541 ggggaagggg gtttaaaatg gatataaaac agttgaaata ttttgttgaa atagtgaaat
    57601 ctggttttaa tttatcaata gcatctaaga cacttcacat atctcaacca gcattaagtc
    57661 aaattataaa aaattttgaa gaaagtgaag atgtatattt atttgaaagg tataaaggca
    57721 ggttaaatgg gttaacacca gcaggagaaa gattttatgt aaatgcagaa catatcataa
    57781 atgaatacaa aaatatgatg gaagatttaa gagaagattc agttcaattt aaaggaaaag
    57841 ttagaatagg aatacctcca cttatacttg gaatagcatt ttcagatgta gttgcacagt
    57901 tagttgcaaa taatccagat atagaatttg atatagtaga gaagggtgca tatgacttaa
    57961 atagaatgct tatcttacag gaattagatt atgcagtatt gttacatcca cataaaattg
    58021 ataaaagtgt agtaactgaa catgtgcttc aagaagatga acttacagca tttttaaata
    58081 taaatcatcc acttgctaag aaggataaga tagattggaa cgatttgaat gagcagttac
    58141 ttgcaatatt taatcctact tttatgatac atcataagct aatgcaaaaa tttactgatg
    58201 aaaatgttaa gttaaaaaga tatataatgt ctggttcatg ggattttttg ttgctatcaa
    58261 ccacaaattc tgattttata acaattctac catcaccagt tcatgatttt tttgaaaata
    58321 gcaaaattat agaaaagcct tttaatcatc ctattacatg gaaagttata ttatgtagac
    58381 ctaaaaaaga acgttatagc catgtagacc aacatgtatt taaatttatt atagatttct
    58441 ttagtaaaaa gaactcttaa aaatgttatt aaaataacaa ataaataaat caatttttat
    58501 tataataaac tattagtttt tcatctatat gtttgagagc aataataggt tttacataac
    58561 atggtagagt agtatttaaa gttataatat acaaaatatg tattttttta aacgaaaaat
    58621 aaaaacagtg tatatcttta gataatcact gtttttattt tctatataaa atttgttaag
    58681 tattactaga aaattttttg cttattatag tcaaactcat gactgttaaa aatataagta
    58741 atcctggaaa tacagctaaa tataacttgt caaaaatatg tctttgagca tcttgaagca
    58801 tattacccca tgatgcaaga ggcaattgga ttccaagacc taaaaaacta agagcagatt
    58861 cagttaagat agcattagca atatttaacg aaccagcaac tacaatagtc tcttttaagt
    58921 ttaaaactat atgtcttaat agtatatttc tagtcttgat accagtagct ttagcagcta
    58981 gacagtattc attttccttt atttttaatg tttcgccacg tacaattctt gaaacttcca
    59041 tccaacttaa gaatccaata attagtataa tagtggaaac tttaggtgtt agataagtat
    59101 ttaatacaat caaaactaag aaacttggta tactcataag catatctatt aatctcatca
    59161 agaattggtc tagcttacct ccaatatatc cactaataac acctacagca gtaccaaata
    59221 ctacagaaat aagcattgat aaaataccaa cactaagtga aatccttcca ccataaagag
    59281 ctctagagaa gtaatctcta ccaagttcgt ctgtaccaaa gatatgcttt aagctaggtt
    59341 cttgaagttt agaagtagta tcaattgcat tagagtctat atttaatata aaagaagcta
    59401 taattaatat gattattatg ctaagagtaa tacatgcaaa agcaaaggat ttatcttttt
    59461 ttaatttttt taagatactt gtaaacacaa ctagaatcct cctttgctag attttatttt
    59521 agggtcaatt aataagtata gtatatcagc aactaaatta cctaaaatta aaaatagtgc
    59581 tgataacata gttattgcca taattacagt ataatctctt gaaaaaattg aatcaatcat
    59641 taatcttccc atacctggcc aagagaaaac tacttctgta acaaatgcac cagtgactaa
    59701 tttttgtata ctcatgccta ggattgtaac caatgatgtc agtgaatttt tcaagacatg
    59761 tttaaatagt atgacttttt ctgataatcc ttttgctctt gctgtaataa catattgttt
    59821 ttttaattgt tcatttacac tagcttctac ataatttgta aaaatagcag tattatatag
    59881 acctaaagtt attacaggca aaactaaatg ttttactaag tctccaatac tatcatttcc
    59941 aatagtatgc atacctcctg atgggaaaat gttaagttta actgaaaaaa ttgaaatgag
    60001 tatcatacct atccaaaaag aaggtataga aacacctata taattaaaaa cagatgatac
    60061 tttactagtt attgaatttt tatttacagc taaaaatatt ccaagaggta tagctaccaa
    60121 tattgaaaat atcaaagaag tacccataag aataaatgta tttcccattt tttccataat
    60181 ttgttctgta acgggcatat ggtttatata agaaatacct aagtttccac ttaaagtgtt
    60241 tttcaaccag tttaaatatc ttatatatac tggtttatca agccccatat taacccttat
    60301 attttcaata tcctgtgaag acattaaagg atttatatat gcatctgctg ggtcaccagg
    60361 agctaattct aaaagtccaa atgataatat agatattaag attaacatag gtattaaaac
    60421 ttttactcta ttcaatatta attttaacat aagtaaattc tcctaattaa aagagatgtc
    60481 tcgttttaaa ataataaaac aatattattt ttagacatct ccttttctaa ttaataatat
    60541 aaaattttac atcaattatt ctacatacag tttagaccaa tcttcaaata atattgcagg
    60601 agatggttta gcatctttta ttccttttag atttttttga gctgccatta aattttgttc
    60661 ataatctata gtgtaaatag gcgcatcctt agatatatcc tgttgtattt gcttatatat
    60721 ttcttcacgt ttttccttgt ttaactcagt aaatcctttt tcccataaag catctatttc
    60781 agcattagaa tatttagttt ggttgcaata ttgaccagtt tcaaacatac ctctatatgg
    60841 gtttggttct aatccccaag cataaccatt tacatacata tcacattcag tgctattact
    60901 aaatagtata ttgaagaatg ccttactttc ataaggaact atttcagctt ctataccaat
    60961 ttttttcaac tcttgttgag ctactaaggc atagttttta tgcccaaatc tacctgtgtt
    61021 ataacctatt tttaatttat caattttaac accactttta tccaataagt ctttagcctt
    61081 atttgtatct tggtcatatc cttcaacacc ttcttctgta tagaagtctg cttctggaac
    61141 taatatagat ttagcaggta cagaaccttc ttttccatat gctgattcta tcatttcatt
    61201 tctatttaag gcatatgata aggcttgtct tacttctttg ttagccatgt ttgatatatt
    61261 ttggttaaat acaatgtagt ttaatctttc ttcactataa gtataagttt gtaagtttga
    61321 gtttgatttt gccttttcat atccttcagc agatgtcttc ataagtgaaa tttcgccatt
    61381 atttaaagct gcttcttgag atgcttcatt aggaattatt tttagcgcta tagaatctgc
    61441 cttaggttct ccaccaaaat aatctgcatt cttttcaaat actatgcttt cacctttttt
    61501 ccattcctta aacttgaatg caccagaacc aactggatta ttattttttt ctgacttagc
    61561 tatatttgat tctccttcaa acacatgttt tggtattgga gaaattttag atataccata
    61621 taagaaagat tcacttgcag ttggtaaagt aatcttaact gttaaatcat caattttttc
    61681 tactttaact ggtttctcac ccaccaataa gtattgtctt gatggtgaat tttgtttttc
    61741 gtctaaaact gtattaaatg taaataagac atcttcagca gttattggct ttccatcatg
    61801 ccattttaaa ttggatttta attttatagt taattcctta ctatctttaa aatctacttt
    61861 ttctgctaaa taatttacta aatttccttt ttcataagta taaagaggag cataaactat
    61921 atttgatgca agagagtctt ctttaacgtt tgcaaaagct ccattgatta tatctgggtc
    61981 acttgccata ggtattacaa cagttccacc agatttgctt ccactagact tgtctttatc
    62041 attggaagca caggctgtaa atgtaagcat taatgatgaa actaagatta atgatgccaa
    62101 ttttttaaat ttcatattct tataaaacct ccataaaata atatttaaca catatttttt
    62161 attgtataat agtaatcatt attaaatcaa tatatataga aattaactat tatattatta
    62221 taattaatag aaaaaaataa taaaatgtaa gaaaatgttg taatttaaat ttttataaaa
    62281 tacaatcaaa aggtgtatgt tatcttaagt aattttgctg agaggagaaa ataatgagta
    62341 aagcactaat tgaggttaaa gatttaaaag tttattttca tacagataaa gggattgtaa
    62401 agagtgtaaa tgaagtaagt tttaatataa atgaaggtga aactattgga atagttggag
    62461 aatcaggatg tggtaagtct gtaacagcca tgtctttgat gaagttactt ccaacatcaa
    62521 aaatagaagg tggagaaata atctttcgag gcaaagacat tttaaagatg aatgaagatg
    62581 aacttatggg aataagaggg aatgagatat caatgatttt tcaagaacca atgacatctt
    62641 taaacccagc gtttactgtt ggaagtcaaa tcattgaagg tattatgata catcaagatt
    62701 tatcaaagga agaagctaag aaaaaggtaa tcgatatgat aaaactggta gaaataccaa
    62761 gagctgaaga aatatataat tcatatccac atgaattatc aggtggtatg agacaacgaa
    62821 taatgatagc tatggcttta tcatgtaatc caaaattact tatagctgat gaaccaacaa
    62881 cagctttaga tgttactatt caagctcaga ttttagatat aatgaaaaat ataaaagaaa
    62941 aattaaacac atctataatg atgattacac atgatttggg agtagttgca gaaatgtgtg
    63001 acaaagtatt agtgatgtat gctggcaaaa ttatagaagt ggcagaggtt gttgaattat
    63061 ttaaaaatcc aaaacatcct tatactattg gacttctaaa atcaaagcct gctcttggaa
    63121 aaaacaaaga taaaagattg tattcgattc caggacaagt accaaatcca attggaatgc
    63181 cagattcatg ttattttagt gatagatgtg aaaaagtatg tgataaatgt agaactcaga
    63241 tacctccttt aatagaattg aatagtggtc atagtattgc atgttggtta tataaaaagg
    63301 aggagatata attgaaaaaa gaagagagtt tattaaaagt agaaggtctt aaaaagtact
    63361 ttgaagttaa atctggatta tttgataaga aaattaaatc tgtaaaggca gtagatggaa
    63421 tttcttttga tttaaaaaaa ggagaaactt tggctatagt tggagaatcg ggatgtggaa
    63481 aatcaactgc aggaagaacc attcttagat taattgaaaa aactgaaggt aaagttgaat
    63541 ttaatggtgt agatatatat aagttagaga aggaagaact tagaaagtta agacccaaaa
    63601 tgcaaatgat atttcaagac ccatatagtt cattaaatcc aagattaaat gtggaacaaa
    63661 taatatccga ggcagttata gaacataatt tagtgccaaa gaatgaaata aaagataata
    63721 tattaaatgt tgtagaaagt tgtggtcttt ctaagtacca tttaaataga aaaccaggtg
    63781 agttttctgg aggtcaaaga cagagaatag gtatagcaag agcattagca ttaaatccag
    63841 aatttatagt ttgtgatgaa cctgtttctg cactagatgt ttctattcaa tctcaaatta
    63901 taaatttact tatggattta caggataaat ataaactttc atatttattt atatctcatg
    63961 atttgagtgt agtaaatcat attgcacata gagtttgtgt tatgtatcta ggttctataa
    64021 tagaaattgc aactaaagga gaactttact tacattctca acatccatat acaaaagcac
    64081 ttatgagcgc agtaccaata caagacccta caattaagaa aaatagaatt atattaaaag
    64141 gagacatacc atctccaaca aatccaccaa gtggatgtaa gtttcataca agatgccctt
    64201 attgtaagga aatatgcaaa aaagagattc cagttttaaa agaaatatca agaaatcatt
    64261 ttgttgcatg tcatctagta tagatatttc aaaaattaaa tttgatgtat ataataagaa
    64321 taatagaata aactgaaaat ttttttgatt aagatgggat ttcatgctgt taatattaag
    64381 ttagttgata tataagttta atctataata ttattattga aaagagaggt agttatgtca
    64441 attttagtaa cattgttggg attattggtt tgtacaacga tttcaactgt atttagcaaa
    64501 aagtggagta atattcctct tgcaatatat caaattgtac tagggattat attgtctatt
    64561 ttgccattta aattctcatt ttcatttaat ccagaaatat ttgtaatatg tatcatagct
    64621 ccattactat tcagtgaagg acaaaatgta tcgagaaaag agctattaga gcttagaaaa
    64681 ccaattttgc ttcttgcatt tggtttagtt ttaataaccg tgtttgcagg tggaatcttt
    64741 atacattttc ttattcctgg gatgccatta tctgtttcat ttgctttggc agcagtaata
    64801 tctccaactg atttagtagc agtaaaatca attacacaag gattaaattt tcctaaaaat
    64861 ataatgagta tacttgaagg tgaatcttta ttaaatgatg ctgctggagt agtagcattt
    64921 aaggttgcag tacttgctac agttacagga gttttttcaa tagaagaggc agggattcaa
    64981 tttatgatta cagcttttgg aggaataata gtaggaagta ttttaggata cataattata
    65041 aaaataagac ttagtttaca caagtggaat ttggaagaaa ttccaatggt aatagttata
    65101 caaataatga ctccactttt tgtatatttt gtagcagaag aaataggagt atctggaatc
    65161 ctagctgttg taatggcagg gatagctcat ggaattgaaa aagagcattt acaaaataca
    65221 actactaaat taaggataat atcagacaat acttggtatg ttttggagta tgtattgaat
    65281 ggatttgtct ttacactgct tggttttttg ttaccaagta tatatacagg acttagtagt
    65341 aaaaatgaaa atatggcatt ggaattgact tttatttcta ctttaattgt acttatttta
    65401 tttgttataa gatttatatg ggtatattta tggcataatt cttttataaa acctaaaaag
    65461 aatcctttaa ataatttttt tgtaggtttt ttaggtttta aggatgaaga agttataaaa
    65521 gagagtattt ctaaatgtaa atactcacta atagttgcta cttgtggtgt tcatggtaca
    65581 tttacactag caactgcctt atctatacct ttttatttgg ctgataaaga tgtatttcca
    65641 atgagagata ctgttttatt tatatcatca gaagttattc ttataagttt agtattggca
    65701 acaattttac tgccaagatt attaaaaaat aacgtacaag agtcagaacc tttattatct
    65761 gataaagagg catataaact aattttgaaa gaagccattt taaaacttag taatgaaaaa
    65821 gcacaagaag tacaaccagt tatacatgat ttaaatgaac agttggtaga ctcagaaaaa
    65881 ggaatactaa atactccaga taataaactt ataagtatga tgattgcaga agcagaccaa
    65941 cagggattat tagctgtttt gaaactatta gaagatggta aaatttctga tagagccttt
    66001 aaattgtata gattttatat tacaaaatca agaaaatctg ttcaaaaatc tatatttaaa
    66061 attgtaaaat taaaaataag catgtggatt ataaatagaa aagtaaagaa agaagtaaaa
    66121 gaaaaaatta caaaaatagt atctgagaat aaagaaataa tcaaagagtt tcaccatgca
    66181 tatgcacttt ctactaaaac tgctatatca tttataaata aaaatactga tgaagataac
    66241 agacatgagg ccttaatagc aatcagattc tataatcgtt atttgaattg gattactaga
    66301 aagattcaaa atgatgataa gtttgaggca agagtagaat actacagagt aatggcgata
    66361 caaagtcaaa gagacagtgt tcaacaatta gttgaaacta agcaaatatc aagagaagtg
    66421 gctaaagagt tattggaaaa tattctctat gatgaaatga tgatgataga atcataaata
    66481 taatggaata aaatttgatt tttgatgtta aaattaatac taaaaaatag gaaatagttt
    66541 tcaataattt acttgacata tatatttatt tataatagaa taaaaccata aattgaatac
    66601 aatatataag cattaacaag ctggattgtt actggtaagc aggcaatacc taggttaagg
    66661 tatacaggtg aattgtatct taatttaggt atttttttat gaataaggga aattgtattt
    66721 tgggagagat attgattatg attattcaac aaatttataa taataatgtt gtattagttt
    66781 tagatgaaaa tataaaaaaa gaattaatat taacaggatg tggaattggg tttcaaaaaa
    66841 agaaaggtca agaaatagat aaaagtaaaa ttgaaagaac ttttgtaata caagatgaaa
    66901 gctttttaga taaaattagt aaactagcaa gccaggttga tgagaaattt tttgaggtta
    66961 gtactgaaat aattgcttat gcagaggaga acttgaatac taagctttat gaatatattt
    67021 atgtagcact tactgaccat attgcatttg caattaaaag atatcatgaa aacataacta
    67081 taaagaatga tttactacat gagataaaaa gaatacataa aaaagaatat gagattggga
    67141 aatgggctgt agattatata aataaagaat ttgatgtgaa atttccagta gatgaagctg
    67201 gttttatagc aatgcatata gtaaattcaa actataaggg aagttcaaag gaatcactat
    67261 taattactaa aattgtaaaa gacatactaa atattataag atattattat agagttgaat
    67321 ttaaagaaga tgatataaat tatgataggc ttctgactca tttaaaattc tttgcaaaac
    67381 gattagtaaa aaaagaaaaa atcaatgata caaataatga aattatagat ataattaaag
    67441 taaagtatga aaaggattat gattgtgcat ataaaataaa aactcatgta gaaaagaatt
    67501 atgattacta tgtaagtcaa gatgaactac tttatttaac attacatatc aaaagagtta
    67561 tatctgtact gaatttataa taaagagtag tttaatacag aatgtataga tttaatatat
    67621 tatgtttaat tttaatatat tatttaaaat ttaatataaa ataataattt taaaacatta
    67681 agattgttac tgataatgca ggcaagactt atgtttataa aaaaattata atagtttatt
    67741 tttaattctg aaattaggtt aatataggtt tatttatatt aacataagtt taattttaga
    67801 attaagtata ctaatgtaac tttttataaa cttaagtctt ttttatttaa aaaaatataa
    67861 aataataagg agagaaaagt aaatgaaaaa agtatttggt gttttacaaa aagtaggaaa
    67921 atctctaatg ctaccagttg cattacttcc tgcagcaggt atattacttg gcgtgagtaa
    67981 tgctttagca ggagacgcat tgttggctca ttttccagct ttggcgaatc ctacatttca
    68041 acttataata agtataatgg aaagttcagg tcaaattata tttaataact taccacttat
    68101 atttgcagtt ggggtagctg ttggtttaac tgaaggagaa ggtgttgcag cattggcagc
    68161 catagtaggt tttttaattc tcaatacatc tatgggtgtt atggcaggtg ttacagaaga
    68221 tatggtagac aattctatgt atgcaaatat tgttggaata ccaacaattc aaacaggggt
    68281 atttggtggc attattatag ggatagtggc tgcttatctt tataaaaagt tttataaaat
    68341 tgaattacct cagtatctag gtttttttgc aggtaaaaga tttgtaccaa tcgttacttc
    68401 attagttgct atagcaatag gaattatatt gtcttttatt tggcctccaa tacaagaggg
    68461 attacttagt ttctcaaaaa atgttataga agcaaatcaa acactagcag catttatgga
    68521 aggttctttg gaaagactat taataccatt tggtttgcat catgttttcc ataatccatt
    68581 ttggtatcaa tttggagaat atgtaaataa agctggtgag cttgtaatgg gtgaccaaaa
    68641 gatattcttt gctcaactta aagatggagt aaatttcaca gcaggtactt ttatgacagg
    68701 tgcatttcca tttatgatgt ttggtcttcc agcagcagct cttgctatgg tgcatgaagc
    68761 aaagccagaa aagaaaaaat ttgtagcagg tataatggca tcagcagcat taacctcttt
    68821 tttaacagga ataaccgagc caatagagtt tgcgttttta tttgttgcac cagtattatt
    68881 tgcaatacat tgtttatttt caggtttatc atacgcaatt atgcaattat taggagttaa
    68941 aattggattc acattttcag gaggattaat agatttctta ttatttggtg ttcttcctaa
    69001 tagaactcca tggtacttgg ctatcttggt aggtattggt tttgcagtat tatactatag
    69061 tgtatttaga tttatgataa gaaaatttaa tttaaagaca ccaggaagag aagatgagtc
    69121 agaaactaac gctgaagtca ttgaaatgtc taagaatgaa ttagcatcag agattttgat
    69181 tgctttagga aataaagaca atttaaagag cctagatgcg tgtataacaa gacttagatt
    69241 ggttgtaaat gatataaata aagtagataa agaaaaattg aaatcacttg gagcagcagg
    69301 tgttatggtt attggcaaca atgttcaagc tatatttgga ccaaaatcgg attcaataaa
    69361 gtctgatata aaagatataa tagagggaaa aacaaaggtt gaaagtactg ttactaaaaa
    69421 tgttgataaa aataaagtga aaaaaaatat ggaagttgca aatatggaaa atgctttagt
    69481 agaaaagatt gattcattaa caaatggaga gatattagat atagaagaag tgccagattc
    69541 tgtattttca agtaaactga tgggggatgg atttgcaatt aaatctagtg atggattgat
    69601 ttattcacca gttgatggaa ctattggagt tatatttcca actaagcatg caataataat
    69661 aaaatcccaa aaaagtggag tagaaatact tatacattta gggatagaaa ctgtaaattt
    69721 agaaggaaat ggatttgaag tatttgtgaa tgtaggggat gaagtaaaag cgggagaaaa
    69781 attagttaaa atggacttag aatatattga aaaaaatggt ctatcaacaa taagtcctgt
    69841 agtatttacg aatttagaac aaaatcagaa attaagcatt aaaaaaggag taagcacagc
    69901 aaaagaggag aatagagtaa gtatattaag agatgatatt gaaaaaatag gatagctata
    69961 tgatagtgta actaaaagtt atgtgggatt taataaatat ataaataggt tcagttaaca
    70021 tgcaatttat ttaatatata ttttaagtaa tagaaatata tatcattata ttttgatata
    70081 ttttaaaaca ttaaaaaact tgaggtatta gtaagataaa tacactaata cttcaagttt
    70141 tattaaaata aaatttacat aaattatcta ttcatctaaa agagtaatat ccaaaggatt
    70201 tttattgttt atataatttt taggagatac cccgtagttt tttttaaatg cccttacaaa
    70261 actagaataa tcgttgaatc cacatttatt acaaacttca ctcataaggt gaccattggt
    70321 tattagtgac tttgccaaaa ttaatctttt ttgaactata taattgtgta tagacgttcc
    70381 agtatgagat ttaaattttc tcataagata atacttactt ataaaaaatt cagacgatat
    70441 gctatctatt gaaagcttat catctatatt tgaatttata tagtttaata ctttcttaat
    70501 agtttcatca taaaaaacat cttctgttga ttccatattt tcatttttta ggaaaattct
    70561 gtttaagaat atcataagtt gtataaataa tgcatttctc aatatttcat ttccaaattc
    70621 agtattggat tcggaaatat ttatttgctc aataaaactc ttaatagatt caatatcatg
    70681 tatatttaaa cgcaatctat tgcatttatt ctctgtagct attttaaaac atttttctaa
    70741 gtcactacta gcatcactat tttttttcat aaattctggg ctaatccata ttgcaattct
    70801 ctcataaaag acatttgaat ctataactgg tttatgtatt tcattattgc tgataaagag
    70861 tatatcccaa ggctttagtt tatagggaat accatcaaca aaataagtta catttccatt
    70921 tataaatata attatcttat taaaatcatg attatggtat tcaaattgta tatctttttt
    70981 atctctaata ttaaatattt taaagttatc gtttaagtac ccgattttat tatccatagt
    71041 ttttatagaa gacctttcct cagttatatt atagaaaatt atagagcatt ttttgcaatg
    71101 tttcaagcat ttttaaccat tcacatagta aaaaattctt aatataatat tatatgtagt
    71161 gtaattttag cagaaagagt ttaaagggag gaaagcattt atgaaattaa atgatattat
    71221 acaggggttg gatataatca atatcaaggg tgaattaaat atagatatta ataatgtaca
    71281 atatgattca agaaaggtta caaaaggtac attatttata tgtataaaag gatttgtgtc
    71341 agatggtcat aagtatataa aagatgccat agaaaaggga gcaagtgcat ttcttgttga
    71401 agaagatgta gaaataaaag gatgtacatt tataaaggta aaagatacaa gaaaagatat
    71461 ggcaaaagta gctgataatt tttacaatca tccatctcaa aaatttaacg ttataggagt
    71521 tacaggtact aatggaaaaa ctagtataac tactatacta aatgagatat taactttaaa
    71581 taagaataaa gttggactta taggaactat aaaaattttt gatggagaaa aagacattgt
    71641 ttccaattca acaactccag aaagtataga tttacaatat cattttaata atatgttgga
    71701 taatggatgt gactactgtg cgatggaagt ttcatcacat tcattggcat taaatagagt
    71761 tgatgaaaca gactttaaac taggcatatt tacaaattta acaccagacc atttagattt
    71821 tcataaagat ttagaggatt atagaaaagc aaaagaaaaa ttatttttta agactactat
    71881 ggcaaatata ataaacatag atgatgaagg tggaaaaaag atatatgaaa atataaaagg
    71941 tataaatgta ccttgttaca cttatggtgt tgatactaag gctgatttta tggctagaga
    72001 tataaaatca gattcggatg gagtatctta tagattaata acaccttcat atgaagaagt
    72061 aatatttata ccagttccag gaatgtttac agtatataat actttagcag ttatagctgc
    72121 ttgctatgta cttggcatac ctaaaccaat atataaagaa ggccttagac tttctaatgg
    72181 agtatcagga aggtttgaaa cagttccaaa tgataaaggt ataagcgtaa ttgtagacta
    72241 tgctcatact cctgacgcac ttgaaaatgt actaaagaca actcaacaat ttgcagaagg
    72301 aaaaataatt tctgtgtttg ggtgtggtgg agatagagat actgaaaaga gacctttgat
    72361 gggagcaatt ggacaaaaat attctgattt atgtattata acttctgata atccaagaac
    72421 tgaagaacca gaggcaataa taaaagatat acttgaagga attgacaaga aaaaagaaaa
    72481 ttaccatgtt gttgttgata gggaacaagc tatagcagaa gctataagta tggcaaaaaa
    72541 ggatgatgtt gtaattataa caggtaaggg acatgaaact tatcaaatta taggtaaagt
    72601 taagcatcat tttgatgata aagaagttgc aaatgagtgt ttaagtaaga tgtagcataa
    72661 aaattaaaca aaatacaaga acaaaaatgt aatatcaagc ttcactttga tattacattt
    72721 ttttatatgt aaataattgt aaaatagata atgcaataat ataaacacta atatctatat
    72781 taattaattt attgttgtaa taaagtttat aattttgtat aattacagta aatatggaaa
    72841 aataagtatt attataaaat gtttacaata attgtcataa gataatgatt atacatacat
    72901 agattcgaga aaggcaggaa gcataatgtt aagtgatgca aaaaataata ggtatggttt
    72961 gtccataatt gctgtcataa gtatcttagt aattacaatt tcctgtttga tttatggttc
    73021 aaggttgaat aagacattag gtgaagaaac gaatcaatat ctttcagaaa tagcaaatca
    73081 aagtgtcaat gtgttaaaaa aacaaattaa tggagatata aagttactag agtcaatttc
    73141 aatatttatt gaaggagaag agtcttttga agtagataat atcctttcta tactaaaaag
    73201 acaagctatt aatagttcat ttaaaagaat gggagttatt ttaccaaatg gtacagcata
    73261 cactacagat ggttatatag aagacttctc taaaagagat tatttcttaa aatcaatgca
    73321 aggagaagtg gttataacag gcaaattaaa agatgtaata gaagatgata aaaataccaa
    73381 tagtaatatt aatgtatatt ctgtaccaat ttataaagat aatgaggtta aaggagttat
    73441 atttgccaca catagtacga agttgtatga aaaaatactt tctgtaccta catttaatgg
    73501 aaaaggatat tcttatataa ctagaagtaa tggtgatatt gttttaaatc caagcagtaa
    73561 aaacgccaac tctactaaag aaaatttatt ttcttacatt ggcagaagtg attcaatatc
    73621 aaaatctagt atcaacaata tgaagtcaaa tataaaaaac tttaaatcag gttcattaag
    73681 ttatagtatg tttggaaaag gatattattt aagttatgcc ccaataggaa tcaatgattg
    73741 gtatcttttt tctgaagttc ctaaaactgc tatatctgag aaatcatatg ctattataaa
    73801 acttacatta tcagcatgtg tagtcttgat tataatcttt acggcattaa caatttatat
    73861 actatttata cataaaaaga gtaaggaaaa attggaagaa tttgctttta aagataacgt
    73921 tacaggtatt ggcaattcaa ataaatttaa tcttgaaggg ggaaaatttt tatcctctca
    73981 tgagaaaaag aatctagttt taatttattt tgatatagat aagtttaagc tagtaaatga
    74041 taggtttggg tatgaagaag gagatagagt attaaaggaa atagcagaga taattaagaa
    74101 tatatttaaa gagcaatctg tattttcaag aatttcaaat gacaattttg ctataatatt
    74161 tgaaaagaaa aataatagag agtcaattat agaaatatgt gaacttatac gtaaaaaatt
    74221 gtcaatgata aaaacaagtt tgggagtaga actcaattta attccatcca taggtgtata
    74281 ttttgttgaa gagggagaaa caaatatttc tacctgtctt gacaaagcta tgattgcaaa
    74341 aactacagta aaaagaaaat atttaaaagt ttatgagatt tatgctgaaa atttaaaaga
    74401 aactctcata gaagaacgtg atattgaaca agaaatgcat gatgctttaa aaaatgaaca
    74461 atttaaagtt tatttacagc ctaaggttga tttatcaact actaaaattg taggtgctga
    74521 agcacttgta cgttggcaac atcctaaaaa aggtctaata agtccaggtg tatttattcc
    74581 tatttttgag aaaaatggct ttataacaga attggatatg tttgtattta cccaagtttg
    74641 taaaaatttt aaacgttggg aaaatgaaaa tttccccaca tttcctatat caataaactt
    74701 atcaagagta catcttgaga atccaggctt tatttctgag cttgaaagaa taacaaaaga
    74761 atatgaaatt gaaccaaatt taattgagat tgaattgaca gaaagtgcaa tatttgacaa
    74821 tacaaaaata ttatttaaaa taatgcaaac tttgaaatct gttggattta aaatttctat
    74881 ggatgatttt ggttctggtt attcttcttt aaatatgctt aaagatatgc caattgatgt
    74941 attgaaatta gataggcaat tctttataac agtgggaaat gcaaaaaaga gtcaaattgt
    75001 agtttcaagt attgttcaaa tggcaaagca acttgatata aaagttgttt cagaaggtgt
    75061 tgaaactgta gagcaagcag agtttttaag gtttataggt tgtgatatgg cccaaggatt
    75121 tttatttgct agaccaatgc caatagaaga atatgaaaaa ttaatattag atagatatag
    75181 tttaaataga aaagaaacaa attaaataaa attgtgaatt ataacataaa aatttataaa
    75241 aaagtgaact ttgttaatca atgttcactt ttttatgtaa aaatatacta ttataaaaac
    75301 ataaatcatt gttaggatat tattttagga attattgggc aaagtttatt aatatgtagt
    75361 attttttaca tttgaatgtt tttgaggtaa gagtatatgg gattatagca aaatacttta
    75421 gatagtaata atagtaattt ctataggtgt gttatacata ttttaaaaaa taaaaatata
    75481 atttataaat ttaaatgtta tatatgtaag taattttatt atatcaaaaa aagagttttt
    75541 cataatcatt tatacaaa
//
LOCUS       DAMJVG010000009        72866 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.009, whole genome shotgun sequence.
ACCESSION   DAMJVG010000009 DAMJVG010000000
VERSION     DAMJVG010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 72866)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 72866)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..72866
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.009"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(406..1128)
                     /locus_tag="PC512_000691"
     CDS             complement(406..1128)
                     /locus_tag="PC512_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004398740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HDF2440462.1"
                     /translation="MITIKNLSKSFGDLNVLKNIDLEIAKGEIMVIVGPSGSGKSTLL
                     RCMNLLEIPTGGEIIFEGKNLVDKKTNIDEVRQNIGMVFQNFNLFPHKTILDNITLAP
                     IKLKKMTKEEAEKKAEILLSRVGLLDKKDSYPSQLSGGQKQRIAIARALAMEPDMMLF
                     DEPTSALDPEMVNEVLDVIKELAKEGMTMAIVTHEMGFAKEVADRVIFIDGGSILEDN
                     TPEEVFGNPKHERTKAFLAKVL"
     gene            complement(1187..1864)
                     /locus_tag="PC512_000692"
     CDS             complement(1187..1864)
                     /locus_tag="PC512_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDF2440463.1"
                     /translation="MSLDFSFLSRFGTSFLEGTGVTVSISLVALCFGFIIGIIICMAK
                     ISKSKVLRAISSIYIEVLRGTPLLVQIYIVWFGLPQLGIRFPMLFGIPSEFIASAFAL
                     SVNSGAYVAEILRSGIQSVDNGQMEASRSLGLNYWSTMRYIIIPQAIKNILPSLANEF
                     ITLVKESSIISVIGVVEIMRTADIVKNAAFRALEPLIVAAAIYFVITFTLSRLVGLLE
                     KKLSVSN"
     gene            complement(1892..2707)
                     /locus_tag="PC512_000693"
     CDS             complement(1892..2707)
                     /locus_tag="PC512_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HDF2440464.1"
                     /translation="MKVFKKLLSLGLVLGLTLSLVGCSGGGEKTKLEQIKDNGKLVVG
                     TSAEFPPFEFHKVVDGKDSIKGFDIMLAEEFAKELGVKVEIKDMSFDGLIGALNADQV
                     DIVLAGMSPTPEREKSVDFSELYYLSRNAVIVKDADIDKVKTEDDLKKLRVGVQAGSI
                     QEEYVVNTLKMTTTKSLKAIPDLITELKNGNIDAVVTNEAVSLINVKKYDGIKMANTE
                     VGKDVTEGMAAAIKKSDNNKDFIELLNKKIKELQDGKKIEEFLNEASTEAASN"
     misc_binding    complement(2933..3143)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(3526..5592)
                     /locus_tag="PC512_000694"
     CDS             complement(3526..5592)
                     /locus_tag="PC512_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HDF2440465.1"
                     /translation="MVELIITTNIDIRKLNENQLEAVEHIDGPCMILAGPGSGKTRVI
                     TYRIANMVVNKNIAPTRILAISFTKASSIEMKNRALNLSDDIRLNKVTYGTFHSVFFK
                     ILRYFERYNLDSIFDEKSKRMTIKAILKSLNIENADDDENIGQVINEISYVKNELMDK
                     NEFNSEVLTKDEFLKVYNLYEEQKSKVNKIDFDDMLIRTYYLLLNNKSALEMVRNVYK
                     YILIDEFQDINKVQFEVLKLICSPLNNIFAVGDEDQSIYGFRGARPDFLLEFEQYFNN
                     TKKIILDINYRSKSEIVHTANRLIDKNKNRYEKIIKCSQGDGGSVTYISPHDSEEEAL
                     YIAREIIDEIQKDYVEYSDFAVIYRTNIQSRALVDVFMDMRIPFVVKDSVITIYDHWA
                     SQDILAYLRIGINPKSNKDWLRIINKPFRYISKDSINMVKDEKDFITALINKCNLHPK
                     QVKTINDLEIDLSYLNTLNPKNAISYIRTSLDYDRYVLDYCSNRKIKTNGLVEILNEL
                     ESSATNFNTVTEFLEHIDRVKTELTENNKNKQTEGVIFTTMHSAKGLEFRNVYIIGVN
                     EGTIPHEKSYDICKEEKKEEQLEEERRLMYVAITRAEEKLCISSTLNKYGKKVDKSLF
                     INDIKSPTKKEIDSIGVGDKVYHKKFHEGEIIKKDGIMFTIKFKDRERILDLKTCLLK
                     NIIYTI"
     gene            complement(5669..8698)
                     /locus_tag="PC512_000695"
     CDS             complement(5669..8698)
                     /locus_tag="PC512_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF2440466.1"
                     /translation="MENNLRKNNSIMKKMIFPLIIVMLIQTSLFCATILWGGTIKKLN
                     DNSFDILNERVINRKNYIQNEMLQRWSNTSETEATINSSVKKVLNEKNALIEDVGNNE
                     EINKDIIKSISNDLIYLLRKNSVTGAFIILSDKNINDKSIDSKGEISRTGLYIRDLDP
                     KFNPNDNSDLLIERGSSDIARSFGISMDSYWEPKFSFKSENEQDGDDFFYKPFRAAID
                     NPNVSSSNLGYWGSKFLLTNAGDRLMTYTVPLIYEDGTVYGVLGIDLSVNYLRELLPY
                     SEINGNKKGNYILGVDRNNDMAFENVISNGYSLKEKFWDGLHSNLEQKESYKNIYKIK
                     NKDNECGNGNIYASVQYLDLYNSNTPFENERWALLGIIEEKSLLSFSKRVEKLVIISI
                     AISLLIGLIGIYIASRLFTKPIVLLANKVRNSNPSKPVNLDKINISEIDELSSAIELL
                     SANVADSSSKLSQIIEMVDMPIGAFELYKNAENVFCTKEFFSVFTTEIKFEEYGYMEK
                     NKFLKKLRGLDKYLQESYETENTYIYKFESKDKKLKWIRMNIFEDELKVLGVVVDVTK
                     EFIEKRKIEYERDFDILTNLLNRRAFHSQIQEKFKNKDELKIAAFIMWDLDNLKYIND
                     TYGHDAGDEYIRCAADILKKFISWNGIVSRLSGDEFYVFIYGYESKDSIRDIINSVKK
                     QMNNTLLKLHDGTEFKIRASAGISWYPDDSTNYDELMRYADFAMYQIKNTIKGEVSEF
                     DINIYNKDSFLLSNREELNKLIDGQLVEYAFQPIVDCKGKVFAYEALMRPKIKTFSSP
                     IDVIRLARSQSKLYQIERITWFKALKSFKKYKEKFGDCKLFLNSIPNNNLSKVDFEEI
                     EDLYGEYLNRVVLEITENDKINEDFIEKKKAYIDHWNIEIALDDFGTGYNGDAVLLYI
                     MPDYVKIDMSIVRGIDKDENRQKILKNLISYSNERNIKVIAEGVETKGEMETLINLGV
                     DYMQGYYISKPSFIPEDISDKIKKELKICHENRNDVV"
     gene            complement(8751..10211)
                     /locus_tag="PC512_000696"
     CDS             complement(8751..10211)
                     /locus_tag="PC512_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HDF2440467.1"
                     /translation="MNRCKFAKLIITSMIVLLLTGCSLKKEDNYKLDPENPTSIQIWH
                     YYNGQQKMAFDKLVKEFNDTVGAEKGIIVEAFSQGNVVDLSEKVLDSANKKVGSEDVP
                     NIFAAYSDTAYEMDKLGLLVDMDKYISKEELNEYIDEYVEEGRINSKDEFKLFPIAKS
                     TEILMLNKTDWDKFAKATNSNINDIKTIEGLVETSKKYYEWTDSLTKEPNDGKAFFGR
                     DALANYIIIGSKQLGVEIFSVKDGKVTLNIDEKVMKKLWDNFYVPYINGYFASYGKFR
                     SDDAKTGDILALVGSSSGAAYFPDRVMLNDNESYNIETSVFQAPRFKGEGKYAVQQGA
                     GMAVTKSTKEEEYASVEFLKWFTDKEPNIKFSIASGYLPVKKKTNDLDVIKEVMKKDN
                     LSLSDKVEGSIASSIEQINSCNLYTNKAFDGGTKARQILEYSMLDKAKEDSNKINELV
                     KSGTSKKDAVAQFNNDKNFKTWFESFKAELENAIKK"
     gene            complement(10303..10677)
                     /locus_tag="PC512_000697"
     CDS             complement(10303..10677)
                     /locus_tag="PC512_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440468.1"
                     /translation="MGNKNKNTKYKDKTRERYNKKVENLNKEKLNKINKQSKKVDKID
                     DIINKSSIVLCVLLVVFSLLYLFKLVQLNIIMILLVITVAIQQGLVSFGAFRNKNYVK
                     ALFSIFVIVCFLIAFKYVVNPV"
     gene            complement(10853..11593)
                     /locus_tag="PC512_000698"
     CDS             complement(10853..11593)
                     /locus_tag="PC512_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HDF2440469.1"
                     /translation="MLYDEDEKEENNERWLLTYSDLITLLMIFFVIMYSMSNVDAEKY
                     KQLSQSLNSAFGGSSGVIEGGNSKIEPVVEPGSNDLDTLQNAKFKKIGEEIQKYLNEN
                     GMANSVSLRVQDRGLVISLKDTILFDTGKAIVKDNSRDKIIQIGKMLNEMNSYMRVEG
                     HTDNMSIKNSEFKSNWDLSVMRATNVVQLLIDNAGIAPDKLSAVGYGEFRPIAENSSE
                     EGRSKNRRVDIVLVDSKYDNVENVSKDK"
     gene            complement(11614..12402)
                     /locus_tag="PC512_000699"
     CDS             complement(11614..12402)
                     /locus_tag="PC512_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor protein"
                     /protein_id="HDF2440470.1"
                     /translation="MTTLIFFIVGIASLVVAFVIDGGHVGALFVFSSALVVFGGTIGA
                     VGASTPFPVFKKSIKIMLLTFKNKKPNNIENIIYFKEIATKARKEGLLSIDKEISEND
                     ELDPFIRKGLELMVDGVDAVTIRNILESQIQITSKRHKEGIAIFDSAGGYAPTLGIIG
                     TVMGLVHILGNLSSNPDALGPQISVAFLATLYGVGSANLIWLPIASKLKAINQQEVSE
                     RLLVIEAILSILEGDNSNLMTEKLKIFLNSKELIELEEIGGRAE"
     gene            complement(12490..12580)
                     /locus_tag="PC512_000700"
     tRNA            complement(12490..12580)
                     /locus_tag="PC512_000700"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12544..12546),aa:Ser,seq:gct)
     gene            12839..13603
                     /locus_tag="PC512_000701"
     CDS             12839..13603
                     /locus_tag="PC512_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDF2440471.1"
                     /translation="MLPQERYEKILSILKSDNIIKINDIVQMFDISIETARRDLAHME
                     SIGLLKRVYGGAIPVIASSVELNYVKRKKINSNDKKQIAIKCSEFINTNDTIFMDTGT
                     TVLEVSKNLKDKKNLTVITNSILVANELMNTNIKVYVLGGYLRETEGSFSGPLTLSAI
                     EQFNVDKAILGAGGITLENGISDYHLEEALVRKKMIERSRKSIVVVEPPKFGINSFAS
                     VAPIEHIDTIITSASIDHNIIIEFSQKGIPLVIADN"
     gene            complement(13884..14999)
                     /locus_tag="PC512_000702"
     CDS             complement(13884..14999)
                     /locus_tag="PC512_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutH"
                     /protein_id="HDF2440472.1"
                     /translation="MPFDKIILYIMAVGVLLGALDRIIGNKFGLGEQFEEGFNSMGPL
                     ALGMVGIVCLAPVISDVLGPIIIPIFNLCGADPSMFATILANDMGGYPLAMELAHNKE
                     AGMLAGLVVSSMLGCTLVFSIPVGLGLIEYEDRPFFAKGLLIGLITIPFGGIIGGLIA
                     GFNLSMVIINMIPVIILAVILAVGLKFNSTLMINGSLVFGKFISILITIGLGAAAFQE
                     ITGIVLIKGMTPIREGIQVIGSIAIVLLGTFPILHLLVKVLNKPLTIVGGKLGMDATS
                     AAGLVFTLANSIPVYKMMKDMSPKGKVVNTAWLVCATAALGDHLGFTAGVVPEMITPV
                     VIGKLVGGVLAIALAILMTKDLTLEEEQSIKMKKDAV"
     gene            complement(15040..16566)
                     /gene="glpK"
                     /locus_tag="PC512_000703"
     CDS             complement(15040..16566)
                     /gene="glpK"
                     /locus_tag="PC512_000703"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HDF2440473.1"
                     /translation="MKYVLAIDQGTTGTRAVLINEKSEFVFSDYMEHTQIYPQSGYVE
                     HDPIEIWNNTKTVSNNVLQQAFENGINESDIKGIGIDNQGETVMLWDKNTGKPLYNAI
                     VWQCRRTYDYVENLKNIPGLENKIIDKTGLIIDPYFSGTKIKWVIDNVKGVKEKIKNG
                     EVLAGTLDSWLIWKMTGGKSFLTDVSTAARTMLFNIRDMDWDRELLDIIGVPRSILAD
                     IMPTSGDFGTTDKEAFCGVSIKITASMVDQPAALFGNGCFEPGMVKNTYGTGCFLYMN
                     IGEELNIAGNGILTTVAWKIGDKVTYAYDGGVYIAGAAIQWLRDGIGVIKNYSETDDM
                     ANSISSTGGVYFVPAFAGIAAPYWDQYARGTMVGITGSTKKEHIVRATLESVALQVKD
                     VVDSMNLASGKKIKMLRVDGGITKNNFTMQFQSDILGIPIEIAENPETTVLGVGYMAG
                     LSCGVWNSIDEIRSEFTISKKYIPNMTTQKREEILLGWNQAVKRAMNWENDTKKVCAN
                     "
     gene            16859..17956
                     /locus_tag="PC512_000704"
     CDS             16859..17956
                     /locus_tag="PC512_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HDF2440474.1"
                     /translation="MKKTYLFSPGPVMVTDKVRNSLLHYDICHRGNEFMDLFKDTQQK
                     INKLYNATSNYYSLIVSGSGTSVNECVLSSIFDKEDAVLLVSNGVFGERLEEILSTYN
                     VKTYKPNFEWAEYPDLDILEKYIIENSDIKVIAMVFHETSSGMINPVPELGKLAKKYN
                     KIFFVDAISASAGEYIDVEEFNIDIITGVGGKALGAFPGSAYLCAKESILQNIKENQC
                     KNVYLNLYKHYKVAKSSSQTPNTPNVTLIFALNEALTEFLEDDSKIERYKECSAILRN
                     GMEELGLTFLLPDKYMSNTVTSVFLPKEINVNEFILGLERESGYVVYPGKGKFLDANI
                     FQVANMGEIYPEDCYKFLDILKSKLEIKKVI"
     gene            complement(18409..18921)
                     /locus_tag="PC512_000705"
     CDS             complement(18409..18921)
                     /locus_tag="PC512_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440475.1"
                     /translation="MKVKKFKSGIVMALTVMAIGASLTNVSAMELNKSKEFETKYNEM
                     KMDFQEEYGKEDKFNITLDDEFTKEEVNGAKGIIKTTNKMNNEVVVLNYFDEMKSGIE
                     FELKPKAEKNAILRDEFQQGYGKEDKFKVVLDDEFTKEEVNGAKGIIKTTDKETGEVI
                     VYNYFDELEK"
     gene            19474..20355
                     /locus_tag="PC512_000706"
     CDS             19474..20355
                     /locus_tag="PC512_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HDF2440476.1"
                     /translation="MKKRLIIMILSVVLVLSSILTIFAYSNIKYNNNKLIYSNMIDKK
                     TQNSVKEILKENKINEKDIDTFIKAVNNYNKLQVKILQNNINISKSGYSSINAKQVPY
                     NLEKLQDNWVKKFPDYMDVNCRITAFRLFKDFINSNKKFTGDSIDLNVDLDTIMNNKD
                     AKFSIKDVEKFINFFSAIPAKDTDDTIKISEQIKNEWKKRKISFKNNKNISIINGFLR
                     YPETKNVFIGHTGICIKTKNGILFLEKYGVTSPYQVTKFKNKEDVKNYMFNRLKMSEG
                     EIELPDPIIMENDKLMK"
     gene            complement(20668..21447)
                     /gene="hisJ"
                     /locus_tag="PC512_000707"
     CDS             complement(20668..21447)
                     /gene="hisJ"
                     /locus_tag="PC512_000707"
                     /EC_number="3.1.3.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ"
                     /protein_id="HDF2440477.1"
                     /translation="MKDGHIHSPYCPHGSKDDFEKYVQRAMDVGITEMTFTEHFPYAN
                     GFRDPAPENDSCMSIEDLPKYFNDVKKLKEKYEGKIKINVGSEVDFIEGYEEGIKENL
                     NKYGKELEDSLLSVHIIKIDDDYYCVDYSVEEFQNLIDKLGSIEAVYNKYYETLIKAV
                     NSDLGIHKPKRIGHLNLVRKFNQVFPYDYKGNTILEELIKLIKEKGYELDYNVSGNRK
                     EYCKEPYIDGYLLELVKKYDIPLILGSDSHCAEEINKYDIV"
     gene            complement(21993..22343)
                     /locus_tag="PC512_000708"
     CDS             complement(21993..22343)
                     /locus_tag="PC512_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter"
                     /protein_id="HDF2440478.1"
                     /translation="MIFDKEIVRYHHGHHDHDHCHEHTHGDICHEHPHDHAHDHDHEH
                     SHEESSESKDEKTLKILLVHWINHNETHEEGFREWVEKARAIGKEETAKSIEKAIEYM
                     EEANKMLLEAKKHM"
     gene            complement(22359..22775)
                     /locus_tag="PC512_000709"
     CDS             complement(22359..22775)
                     /locus_tag="PC512_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3842 family protein"
                     /protein_id="HDF2440479.1"
                     /translation="MIIAVIDGMGGGIGAQIVSSLREELPTYVEIYALGTNSIATSSM
                     MKAHANKGATGENAIVVSAKKANIIVAPISVIIPNSMMGEVTCNISEAIADSEALKIL
                     LPIMPENVELVGLEGKPLALLVKDSVNLIKKEFNIK"
     gene            complement(22794..22985)
                     /locus_tag="PC512_000710"
     CDS             complement(22794..22985)
                     /locus_tag="PC512_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CooT family nickel-binding protein"
                     /protein_id="HDF2440480.1"
                     /translation="MCESSAFICKSNNELEKVMENVVNIDPCDGKIYLTDLLGEQKII
                     DGIIKEIRLMDHKIIIQEN"
     gene            complement(23136..23951)
                     /locus_tag="PC512_000711"
     CDS             complement(23136..23951)
                     /locus_tag="PC512_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HDF2440481.1"
                     /translation="MNQWRVIHNKSYEGAMNMAIDEAIFTAYKKGHNKPTLRFYTWEP
                     ACLSIGYFQKLEDEIDLDKCRCMNIDYTRRITGGRAVLHDNELTYSIIIGEDNPLIDK
                     SINLSYRYISEGLVKGLNLSGIETDNLNRGERISRENLSAACFNAHASYEVTINNKKV
                     IGSAQSRKDGVLLQHGSIILDFDVEKLFKLIKTKTPELKERAMKFTAKKASGIENEIG
                     RKIDIDILQKNIVKGLAEQFNVEFVEGDLTDYEKQLVKELYEKYKNEEYNKKR"
     gene            complement(23998..24936)
                     /locus_tag="PC512_000712"
     CDS             complement(23998..24936)
                     /locus_tag="PC512_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF2440482.1"
                     /translation="MIRLSVGTAIELGILNKKSDIPPTTAYIMIGEKCINKCSFCSQS
                     IESSTRKDKLSRVIWPEFSKEEILDALKAYKGKNIKRICIQSMASEEAHNSVLDFINY
                     ISGKIDMPISLSAKLENDEQIKKFFSVGVDKIGIAIDAANKELYEKIKGNNYDEKLKF
                     ITEMSKSYPNKISTHIIVGMGESHEDIYNLYTYLKENDVTISLFAFTPVRGTKMEKIN
                     QPSIESYRRVQLMSYMINKGYPKEYFKFKNGYLNSIKLDNDILKDINKGYPFEIRGCK
                     DCNRPYYNERPGSTIYNYSRPLNQSEIDLAIREINL"
     gene            complement(24933..25805)
                     /locus_tag="PC512_000713"
     CDS             complement(24933..25805)
                     /locus_tag="PC512_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF2440483.1"
                     /translation="MNKNLSEKMEIAFDIKLKNFGNKIEFAYPNQTLALSTTSNQCSL
                     KCAHCNGHYLNNMVPIEEYEEKVQSRNITSFLLSGGCSYEGDVPINTHINTIKNLKEQ
                     GYRLNAHLGLMDKDSIVELCKYLDIVSFDLVFDDETIREVYKMKKSKEDYIEVYNTIQ
                     EHTEVAPHICIGLKGGQIKGEYEIIEYLQKNPPNKLTFIVLIPTKGTEYENVEPPELE
                     GVADILCEARINLPDTEINLGCMRPRGVYRKELDQLSIMCGVNRIVLPSRSAKNKAIE
                     MNMTINECKECCVL"
     gene            complement(25830..27758)
                     /locus_tag="PC512_000714"
     CDS             complement(25830..27758)
                     /locus_tag="PC512_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4445 domain-containing protein"
                     /protein_id="HDF2440484.1"
                     /translation="MIKVSFTPNNKEVYCNEGDILLEVARNADIFIDAPCNGNVSCGK
                     CKVKLLNGKVDTEKTRHITDDEWEQGYILACCTKVISDIEIEVPSKVSSSMHGMKIEG
                     SNKKEDREIFERAKKIIEEHNLQFKTNIKKKYIEMEEPNLDDNISDVDRLERYVRNNL
                     GYNEIDFRLDILRKMPTVFRKSDFKVTITYVQKQKKLTIINIEQGNKENSLYGVAIDI
                     GTTSVVVCLVDLYSKEVVDKASSGNAQIKYGADVINRIIYSTKKNGLETLHKAIVEET
                     INPLLKTIYERNGIDKEDVVTLVAAGNTTMTSLFLGVYTDFLRQEPYIPPFLKSPKLM
                     GENVGLFVNDSAYVYLAPSVASYVGGDITAGVLSAGIWSSEENVLFIDLGTNGEIVFG
                     NKDYMMSCACSAGPAFEGGGISCGMRASAGAIEKVIIDKETLEPTLKIIDECAPVGIC
                     GSGIIDLICQMITKGVIDRRGKIYRDLDNKRVRFNEHEIGEYVLAFKEEFDLENDIVV
                     NEVDIDNFIRAKGAIYSGAYTLVDSLGMDFSILDRVYIAGGIGNNLDIENSIIIGLLP
                     DIDREKFTYIGNSSLVGSYLALISKDAKNKLEEIGNQITYVELSVYPSYMDEFISACF
                     LPHTNIEQFPTAKKLLEE"
     gene            complement(27870..28247)
                     /gene="gcvH"
                     /locus_tag="PC512_000715"
     CDS             complement(27870..28247)
                     /gene="gcvH"
                     /locus_tag="PC512_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein GcvH"
                     /protein_id="HDF2440485.1"
                     /translation="MKLLPELKYSKDHEWVKVIDGDVVYIGITDYAQDQLGEILFVET
                     PEVEDTVTKGVDFGVVESSKVASDLISPVNGEVLEVNEKLEDEPECINEDPYENWILK
                     VKLADVAELDTLLSDKEYEAGLE"
     gene            complement(28334..30460)
                     /gene="cdhC"
                     /locus_tag="PC512_000716"
     CDS             complement(28334..30460)
                     /gene="cdhC"
                     /locus_tag="PC512_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CO dehydrogenase/CO-methylating acetyl-CoA
                     synthase complex subunit beta"
                     /protein_id="HDF2440486.1"
                     /translation="MNLYNIIFTGSEQALGAAQAMLAEAIEKNGKEHKVAFPDTAYSL
                     PCIYAATGQKMNTLGDLEGALEVVKSLINRTHLLEHAFNAGLATALAAEVIEALKYST
                     MDAPYSEPCAGHITDPIIRSLGVPLVTGDIPGVAVVLGECPDAESAAKVIKDYQSKGL
                     LTFLVGKVIDQAIEAGVKMGLELRVIPLGYDVTSVIHVVSVAVRAALIFGGLTPGDLN
                     GLLEYTANRVPAFVNAFGPLSELVVSAGAGAIALGFPVITDQTVLEVPMNLLTQKDYD
                     KIVATSLEARGIKIKVTEIPIPVSFAAAFEGERIRKSDMFAEFGGNRTEAWELVVKKE
                     ATEVEDHKIEIIGPNIDEVDADGVLRLPLAVIVKIAGKNMQEDFEPVLERRFHYFLNY
                     IEGVMHVGQRDMAWVRISKDAFDKGFRLEHIGEVLYAKMLDEFESVVDKCEITIITDA
                     EKVSELKGEAIAKYNARDERLASLVDESVDTFYSCNLCQSFAPAHVCVVTPERLGLCG
                     AVSWLDAKATKELDPTGPCQPIEKGECLDDRTGVWNSVNETVNQISQGAVESVTLYSI
                     LEDPMTSCGCFECICGIMPEANGFVVVNREFASVTPVGMTFGELASMTGGGVQTPGFM
                     GHGRHFISSKKFAYAEGGPERIVWMPKELKDYVADKLNATVKEMTGIENFCDMVCDET
                     IADDSEGVLAFLEEKGHPALAMESVM"
     gene            complement(30517..31323)
                     /locus_tag="PC512_000717"
     CDS             complement(30517..31323)
                     /locus_tag="PC512_000717"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HDF2440487.1"
                     /translation="MEKFMIIGERIHCISPSIRKALAERDPAPILKRAKEQLEAGAHY
                     IDFNIGPAERDGEEIMTWGIKLLQSEFNNVPIALDTANKKAIEAGLKVYDRTNAKPII
                     NSADAGSRFDLIDIAAEYEAMVIGLCAKEGIPRDNDERMAYCQEILEKGLMLGMEPTD
                     ILFDPLCLVIKGMQEKQVEVLEAIKMMTEMGLLTTGGLSNVSNGCPKHVRPVLDSAFL
                     AMAMANGFSSAIMNPCDPELMKTVKSCDIINGASLYADSFLELNEGGFAF"
     gene            complement(31373..32740)
                     /locus_tag="PC512_000718"
     CDS             complement(31373..32740)
                     /locus_tag="PC512_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA decarbonylase/synthase complex
                     subunit gamma"
                     /protein_id="HDF2440488.1"
                     /translation="MALKALDIFKLTPKKNCKDCGFPTCMAFSMKVASGAVEVGKCPH
                     MSDDAIAKLSEATAPLMKALKVGAGASEYELGGETVLFRHEKTLVSRNRYAVSFCTCM
                     SDEAVDAKIANMKKVDYVRIGEQMKVEMAVLEYCGDKDAYLKLIDKIKGSGLEVAYIL
                     ACDDAQVVKEAVEVLKDARPMVYGATKENYKDMIEVVKGASLPLGVKAGSLEELYETV
                     ELIQAAGYKELVLDVTGENIKDTYTNAIQVRRTALKEQDRTFGYPSIVFANRLSNSNP
                     MMEVALSSIFTIKYGSIIVIDDISYAKALPLFALRQNIYTDPQRPMRVEPKIYPINNP
                     DENSPVLVTVDFALTYFIVAGDIERSKVPVWLVIPDAGGYSVLTSWAAGKFGGNSISA
                     FIKESKVEEVTNCKDLIIPGKVAVLKGDIEDNLPGWNVVIGPEESMELPKFLKGYQEK
                     ACQTN"
     gene            complement(32771..33715)
                     /locus_tag="PC512_000719"
     CDS             complement(32771..33715)
                     /locus_tag="PC512_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA decarbonylase/synthase complex
                     subunit delta"
                     /protein_id="HDF2440489.1"
                     /translation="MAFKMSTQKYSGKISEVEVGIGEKAIKLGGENVLPFYSFDGEVG
                     NSPKIGIQISDVYPESWTDSYKELYKDVANCPVEWAKYVEANTQADFICLKFDGSDPN
                     GLDKSVDECADVAKAVIEAIKLPLVVAGSGNHEKDGKLFEKLAQTLDGHNCLFMSAVE
                     DNYKGVGASAGMAYAHKVGAESSVDINLAKQLNVLLTQLGVKGENIVMNVGCSAVGYG
                     YEYVASTMDRIRLAAFGQNDKTLQMPIITPVAFEVGHVKEAIAPIEDEPDWGCPEERT
                     IAMEVSTAASVLVGGSNAVILRHPKSIETIKELVNALA"
     gene            complement(33735..34505)
                     /locus_tag="PC512_000720"
     CDS             complement(33735..34505)
                     /locus_tag="PC512_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2440490.1"
                     /translation="MGYNIAVAGKGGTGKTSLTGLLIDYLVKDKKGPVLVVDADANAN
                     INEVLGIEVEATIGEIREEVNQREKLGNAFPGGMTKAQYLQFRLNSIIEEGEGYDLLV
                     MGRSEGEGCYCFVNGILREQVNKISGHYKYLVMDNEAGMEHLSRKVTRHVDTLLLVSD
                     CSRRSIQAVARIRDLAEELKLSVGRILLIVNKVPNGVMNDGVKEEIEKHNLELIGVVP
                     MDELIYEYDSTGIPLVNLPEDSKSKVAMKEIFAKLELK"
     gene            complement(34561..35946)
                     /gene="lpdA"
                     /locus_tag="PC512_000721"
     CDS             complement(34561..35946)
                     /gene="lpdA"
                     /locus_tag="PC512_000721"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HDF2440491.1"
                     /translation="MKIVVVGGGPGGYVAAIKASMLGADVTVVEKRRVGGTCLNAGCI
                     PTKALLASSGVLNTVKEAKDFGIEIDGTVKPNFTAIMERKNKVVNQLISGIEFLFEKR
                     GVNLVNGFGKLIDKNTIEVTKDDGTVETIKADKIILANGSVPVVPRMFPYDGKVVITS
                     DEVLGLEEIPESMLIVGGGVIGCEIGQFFRALGTEVTIVEMVDQILLNEDKDVAKQLL
                     RQFKKDKIKVITGIGVQTCEVVDGKAVATLSNGKVIEAQYALVCVGRRPNLDNSGVED
                     IGIEMERGKVVVNEHLETNVEGIYAIGDIIDTPFLAHVASKEGIVAVENALGKTKVVD
                     YRAIPRCVYTEPEVAGVGKTEKQLEAEGVEYNVGQFDFRGLGKAQAIGHFQGFVKVIA
                     DKETDKIIGAAVVGPHATDLLTELSLAVHLGLTVEQVGDAIHPHPSLSEGLMEALHDV
                     HGECVHSVPKL"
     gene            complement(35990..36871)
                     /locus_tag="PC512_000722"
     CDS             complement(35990..36871)
                     /locus_tag="PC512_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase"
                     /protein_id="HDF2440492.1"
                     /translation="MSLLRETLESGKFAVTTEMAPPKGTDLSHLIECAKPLVGRVHAA
                     NVTDFQSAVMRATSLATCKLLKDAGLEPVIQITGRDRNRIAIQGEMLSAGVFGINNLL
                     ALTGDHTSVGDHPQAKGVFDLDSVGILQTAETLMAGTDMAGNKLKGSPDFYLGASVTP
                     EYSPIEVQLLKMKKKIKAGAKFFQTQALYDINTMRKFRELTRDMDCKVLAGIVPLKSP
                     GMAKFMTANVPGIFVPDEQIERLRAAGKENWVSEGIKMAGELIKQLKEEDLCDGVHIM
                     AIGAEENIPAILDAAGL"
     gene            complement(36907..37581)
                     /locus_tag="PC512_000723"
     CDS             complement(36907..37581)
                     /locus_tag="PC512_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase C-terminal
                     domain-containing protein"
                     /protein_id="HDF2440493.1"
                     /translation="MIISENKPLEEVLGYLKDFDKLVLVGCNQCAATCKSGGEEEVLK
                     MKETLEGEGKKILGYVMLDPACNLLKSKKDLKALKEETKEADAVLSLACGDGTQTIVK
                     NLKDKPVYPANNTLFIGEVQRVGEYEEACKACGDCELGWTGGICPVTMCAKGLMNGAC
                     GGAKNGKCEVNSENDCAWIKIYERLEAIGQLDNLAEIRPPKDYSKQNNPRSLSAKKKK
                     EAAANS"
     gene            complement(37618..38490)
                     /locus_tag="PC512_000724"
     CDS             complement(37618..38490)
                     /locus_tag="PC512_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 5,10-methylene-tetrahydrofolate
                     dehydrogenase/5,10-methylene-tetrahydrofolate
                     cyclohydrolase"
                     /protein_id="HDF2440494.1"
                     /translation="MEGMSTKGQIIKGKPVADKISEELIKEVDLLIKEGINPKLTIVR
                     VGARSDDLSYERGALKRCQNIGITTEVLELAEDITQEEYIDVLKRVNDDKNVNGILCF
                     RPLPKHLNEEVIKYVIAPEKDVDCFSPINSAKVMEGDKSGFPPCTPTAVVEILKHYNV
                     DLKGSKVTVLGRSMVVGKPVSMLLLSEHATVTICHSKTKNLSGVAAEADVLIAAIGRA
                     KMVDESFVKDGAVVIDVGINVDEEGNLCGDVDTNAVLDKVSMITPVPAGVGSVTTSIL
                     AKHVVKACKLQNNK"
     gene            complement(38582..39214)
                     /locus_tag="PC512_000725"
     CDS             complement(38582..39214)
                     /locus_tag="PC512_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclodeaminase/cyclohydrolase family protein"
                     /protein_id="HDF2440495.1"
                     /translation="MKIADKTCVDFVEVLSSKEAVPGGGGAAALVGAIGMALGSMVCN
                     LTIGKKKYAEYEESVKEILSKAGKLEKDLLKMIDDDAECFLPLSKAYGLPKETEEEKR
                     IKAETMEKALKVACEVPLNIVRVCYEAIKLHEDLVDKGSRLAISDVGVGVQCLRAAIL
                     GGQLNVVININSIQDKEYVNKVKTEVDKLVEDGVKICDEVYAKVEKALGK"
     gene            complement(39319..40995)
                     /locus_tag="PC512_000726"
     CDS             complement(39319..40995)
                     /locus_tag="PC512_000726"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014355320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HDF2440496.1"
                     /translation="MGFKSDIEIAQEAKPQDIREVAKKLGLGEDDVELYGKYKAKVDY
                     NLLKRETGKKAKLILTTAINPTPAGEGKTTTTIGVADAFAKLDKNVLVALREPSLGPV
                     FGVKGGAAGGGYAQVVPMEDINLHFTGDFHAIGAANNLLAAMLDNHIHQGNALRIDPK
                     KITWRRCVDMNDRQLRNIVDGMGKKGDGAVRQDGFDITVASEIMAAFCLASDISDLKE
                     RLGNIIVGYSYEGEPVTARQLKANGAMAALLKDALKPNLVQTLEGTPSFVHGGPFANI
                     AHGCNSVIATRMAMHFADYVITEAGFGADLGAEKFLDIKCRMANLKPDAVIIVATVRA
                     LKYNGGVAKADLNNENLEALEKGLPNLLKHVENITQVYGLPAVVAINRFPLDTEAELK
                     LVEDKCKELGVNVALSEVWAKGGEGGIAVAKEVLRLLDEEENNFRFCYEDDLSIKDKI
                     NAIATKIYGADGVDYTPEADKEIANLEKLGFTKVPVCMAKTQYSLTDDQTKLGRPTGF
                     RITVRQATISAGAGFIVALTGEIMKMPGLPKVPAAEKIDVDENGVIAGLF"
     gene            complement(41244..42023)
                     /locus_tag="PC512_000727"
     CDS             complement(41244..42023)
                     /locus_tag="PC512_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2440497.1"
                     /translation="MKIAITGKGGVGKTTFSSMLSRMFAEDGYRVVAVDADPDANLAL
                     ALGFPKEVYESIVPISEMKKLVSDRTAASVGSFGKMFKMNPKVDDIPENFCKEYNGVR
                     LLTLGTVDSGGTGCVCPEHVLLKRLCSHLILQNKDVVVMDMEAGIEHLGRGTAQGVDA
                     FIVVVEPGERSLQTYRKVKKLGHDIGVNKVFVVGNKIRNKEDEEFIIQNLEDGESLGF
                     IYYNQDVIDSDRANQSPYDSSETTKEQIKAIKDKLMSLKDK"
     gene            complement(42333..44252)
                     /gene="cooS"
                     /locus_tag="PC512_000728"
     CDS             complement(42333..44252)
                     /gene="cooS"
                     /locus_tag="PC512_000728"
                     /EC_number="1.2.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic carbon-monoxide dehydrogenase
                     catalytic subunit"
                     /protein_id="HDF2440498.1"
                     /translation="MDEKMLTIDLNSQKMIAKAREEGVETMYDRKEGFKAQCGFGLQG
                     VCCRICGMGPCRISPKTPRGLCGADEHTIVGRNFARMVAGGTAAHSDHARDIAHTLAL
                     ADPNGNYKIRDEAKLITLAKEWDVETEGRDIYDVAHEVAEIALMEFGKPFGTLRFIKN
                     APEPRQKIWKEYAIEPRAIDREIATIMHSTHIGCTGDIDSLIHMSLRTSMADGWGGSM
                     IGTRLSDILFGTPVPRRTEANLAVLEENKVNIILHGHEPALSEMIVLASEEPDLVALA
                     KEVGADGINLAGMCCTGNEITMRHGVKIAGDFHQQELAIITGAVEAVIVDVQCIFPAL
                     ARVADCYHTKFVTTSPKAKITGSTYIEFREEQALDDAKAIVKEAILNFKNRDKSKVLI
                     PELKSGATVGYSVEAVVNQLDRVVNSHIDPAGTVKPLTDCLKAGVLRGAAGVVGCNNA
                     KGVSNEAHVTIMKELIKNDIIVVTTGCGASAAAKFGLMESDAAEKYAGKGLATVCKLV
                     GIPPVLHMGSCVDISRILDLVGAAANYLDMDMCDLPVVGIAPEWMSEKAVAIGCYVVA
                     SGIDTYLGIMPPIAGSSRAVDILTSELKDKVGATFTVNTNPKELAATIIEDIEKKRVH
                     FEALVEEKMAEKAEA"
     gene            complement(44859..45770)
                     /locus_tag="PC512_000729"
     CDS             complement(44859..45770)
                     /locus_tag="PC512_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional enoyl-CoA hydratase/phosphate
                     acetyltransferase"
                     /protein_id="HDF2440499.1"
                     /translation="MIKKLDDILEQLKGGEKIVLSVAAAHDKEVLMAIKDAVERNIIT
                     PILVGNEGKIREISKEIGFDLSGIKIVDKDDIKECAEIAVKLVSSKEADFVMKGLLDT
                     SVILKEVLNKDYGLRTDSLLSHVMVYELEKYHKLLITTDGGMNIAPDYEQKAKILKNS
                     IKAAKALGMETVKVACLAAKEKVNPKMQATVDADMLAKACKEGEFGENVIVEGPLAFD
                     LAVSKEASEIKGFKSEVSGDVDIILVPTIEVGNGIGKAFTYMADSKSAGIIMGAKAPI
                     VLVSRADSHESKLYSIAYGAIVAKNMK"
     gene            complement(45886..46464)
                     /locus_tag="PC512_000730"
     CDS             complement(45886..46464)
                     /locus_tag="PC512_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HDF2440500.1"
                     /translation="MNINEFLTHINQRKPVSSKSEIHEFMVKLSNEAMKITSKLNSSY
                     HEPEEVRSLFSELIGKKVDESFFMFPPFYTDCGKNITIGKNVFINSSCHFQDQGGIEI
                     GDNTQIGHNVVLATLNHGIAPEKRGTTYPSPITIGKNVWIGANVTVVPGVTIGDNAII
                     AAGAVVTKNVAENTIVGGVPAKLLRAIDEIPE"
     gene            46690..47613
                     /locus_tag="PC512_000731"
     CDS             46690..47613
                     /locus_tag="PC512_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF2440501.1"
                     /translation="MEIRVLRYFLAIAREESISGAATFLHITQPTLSRQIMELEEELG
                     VKLLVRGNRKITLTNEGRLLHKRAEEIISLVDKVELEFDNPNEIISGDIYIGSGETEA
                     MRLIARTAHHFHQKYPNVRYHLFSGNADDVTEKLDKGLLDFGILIEPANIQKYDYAQI
                     PATDVWGLLMRKDSALASQSTINPKDLCNIPLIISRQTLVDKAISKWLQGSNEKLNII
                     ATYNLVYNASLLVEEGLGYALCLDRLVNTTENSNLCFRPLSPPLEAKLNIIWKKHQIF
                     SKAAEKFLLQIQKDFSSIMLDTSKLDTPKEK"
     gene            complement(47785..48927)
                     /locus_tag="PC512_000732"
     CDS             complement(47785..48927)
                     /locus_tag="PC512_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HDF2440502.1"
                     /translation="MDFKIEKYLLKKAEELAFITIKHGGEFKLKSYEVPKGGLDVPIK
                     NEVLVKGIKEKTAQDKLNSMSIADAMIYIIGIDSKFKNNAEYEKFLNALSKDIDLDLK
                     SYMGYMSRKYFEIGEHTDSLIYIKAFITMYPDDLDAMYNYAIVCQEIAKQYQKDMDDK
                     AMNAFLLEAMAKLEKVIDVDENFALGYYHLGYHYYNQGQYLKTKLTWEEALRLGLDAD
                     LVAEVQENLGKMDFKVQYEEGYTLVFQGKFKEGLEKLLPLEEEHMDWWNLLFMIALGY
                     KGMGEIEQAKMYLEKILIIKPNQVDTIVELGLCEAYKNNLDKAIEYFEQAAKIKEDPE
                     ILCNLGMAYLNNGDIDDATYYIERAYELNPQDEITIACLRELGINK"
     gene            complement(48945..50699)
                     /locus_tag="PC512_000733"
     CDS             complement(48945..50699)
                     /locus_tag="PC512_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B12-binding domain-containing radical SAM
                     protein"
                     /protein_id="HDF2440503.1"
                     /translation="MKILLTTLNSKFIHTNLAIRYLKEFVRDLIEVNMKEYTINNDLD
                     YILKDIYKNEYDIILFSTYIWNVGDIVKLCDNLKKIRPNTKIALGGPEVSYDSYEAMK
                     KYDFVDYILYGEGELIFRDLVLHLQGKMEINDVNGLVYRQGNEIIVNKPMELLQDLDE
                     IPSPYENLNPKEYENRIVYYESSRGCPFNCQYCLSSTIPGLRYFSLDRIKSDLKALID
                     ARVSQIKFIDRTFNANRKVAMEIMDFLMKNDNGYTTYHFEVTAYLIDDKMLEFLADCK
                     EGLFQFEIGVQSTNEKTLDAVGRRDDFKKLSHVVQTVASYRNIHQHLDLIAGLPYEDY
                     KSFENSFNDVFNLGIEHLQLGFLKMIKGTGMRKVADEHGFKYKDYAPYEFLYNNYISY
                     EETLKLKDIEDILERYYNSKNFVLSMRYIIGRFYKKSPFKFFEVFAKYFDENGYFDLA
                     QGKNQLYKILMDFYNEKINIDNDVFNDILKYDYISLGKTSNIPQFFNKLDVDDFKNRC
                     HVFLQDNDNLSTYLPSFVDKPAKHIIKYVHFEPFRFNVVDLKNDINTEIREVENVVLF
                     EYDDKKIFEKSKTHKVEI"
     gene            50835..51041
                     /locus_tag="PC512_000734"
     CDS             50835..51041
                     /locus_tag="PC512_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440504.1"
                     /translation="MELIEKVSINSLSKRDLLLIIKSLEYTNENTQISDFIDLRNNIV
                     KELCFLTDTKEKDFLDYLEKNSTL"
     gene            complement(51046..51969)
                     /locus_tag="PC512_000735"
     CDS             complement(51046..51969)
                     /locus_tag="PC512_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440505.1"
                     /translation="MNDELLKKVYTSSFSSASRALKDLTIINTKSLIDDKTQRCVYID
                     ENRLRDELIYYRFYGEKIGNINFLNILLPLILSNTNIQKSEDEVIKLIKKYVIYFKKE
                     ELLFDYLLGSVVYNSIMHNLINNSKIEYVELLQSIKDKIIGFSIELDKSDVVKFQMAR
                     IKAIQLIDKYIDLKSEDYDEESILLNVLNVLYDVYMEDRTVENEGINSIKKSILSILG
                     EDSKLNEDNIDFIFSMSEYVVKLRKYKIGVKAYNKSIDPRSLIRLEEGNTIVDPIFNQ
                     ITVMSKTFNDNILSIKINSKSGIYILKFKKV"
     gene            complement(52223..53923)
                     /locus_tag="PC512_000736"
     CDS             complement(52223..53923)
                     /locus_tag="PC512_000736"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HDF2440506.1"
                     /translation="MQDFKVAISNCLKEKIEDLSKEEIEALIEVPPNKDMGDYAFPCF
                     KLAKVFRKAPNMIASELAESIEPSGEITKVIQLGGYVNFFVNKSQLAETVIKKVLDEK
                     ENYGHSDFGKDKTVIVEYSSPNIAKPFHIGHIRTTVIGNALYKIYDSQGYKTIRINHL
                     GDYGTQFGKLIVAFKKWGEKEVVESNPIPELLKLYVRFHDEAEQHPEMEDEARAWFNK
                     LENGDEEAQELWQWFRNESLKEFNRVYKLLDIEFDSLAGESFYSDKMNRVIELLEEKN
                     LLKESKGARIVDLEEYKMPPALITKNDGSTLYMTRDLAAAIYRKETYDFDKCIYVVGS
                     QQNLHFQQWFKVIELMGYDWAKDLIHVGFGMVALEEGTMSTRKGRVVFLEDALNQAID
                     KTKEIILAKNPNAKNVDEISKQVGVGAVVFQELSNSRIKDYTFSWERTLSFDGETGPY
                     VQYTHARCCAVLRKAEVEVTSDIDYSLLADEDSAEVLRVIESFNKNILLALKKNEPHI
                     VTRFMLDLAQAFNKFYHDNPILVENLEIRKARLALVLATKQTLENSLKLLGMHAPERM
                     "
     gene            complement(54333..54746)
                     /locus_tag="PC512_000737"
     CDS             complement(54333..54746)
                     /locus_tag="PC512_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HDF2440507.1"
                     /translation="MILVSACLIGINCKYSGDNNDNEKVKEYLKGKEFTLVCPEQLGG
                     LSTPRPPAEIVDGKVITKDNKDVTENFVRGANETLKIANLYVCSEAILKEGSPSCGCN
                     LIYDGSFSGKKIPGKGITARLLEEEGIKVKSEKDL"
     gene            complement(54812..57190)
                     /locus_tag="PC512_000738"
     CDS             complement(54812..57190)
                     /locus_tag="PC512_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HDF2440508.1"
                     /translation="MNEKSLRVLEYNKIIDLLKKKASSSLGLKYIENLVPNTDFVEVK
                     SMLEETSEAQSIIIKRGSVGLEGIHDIEDKVKRAYIGASLDPGSLIMIADTLRVARRL
                     RNSLSSSDEEDFNYPIIQSLSNSLYVYKDIEDQIYNAIISEVEISDNASSTLRDIRRR
                     IAQKNQSIRSKLNSIISSTTYQKYLQDAIISLRGDRFVVPVKSEYRSQVAGIVHDQSS
                     SGATLFIEPMTIVEMNNELRQLKLGEQEEIERILSELSAMVGEVSEDLISNQEILGRL
                     DFAFSKGKLSIQMRGIEPTLNEDKYLNIKNGRHPLLDKKKVVANTIYLGRDFHTLVIT
                     GPNTGGKTVTIKTVGLFALMTQSGLHIPADYGSSMCVYDNVFADIGDEQSIEQSLSTF
                     SSHMTNIVSILQNVTADSLVIFDELGAGTDPVEGAALAIAVLEDINSVGAKCIATTHY
                     SELKNYALTKPGVENAAVEFDIETLSPTYKLLIGVPGKSNAFEISRKLGLSDYVISRA
                     KEYINTENIALEDVLQNVEKNRIKAVEDREEAERLKEEIEKLKVEYDEKLEKLVSQRD
                     KMIEKAKSEAFSIIRQAKEEVDIIIKELRSLEQERASKEKNRKIEELRKELTSSMGSL
                     QPTVKSMIVPKVSNKEIKDLKPGEEVKVITLNQNGSVVSVDKKRKEAVVQIGIMKMTL
                     PFKSLQKTRKDVSTNVTKSTRNIIRSKSGSVKNEVDLRGLNLEEAIMEVEKYLDDAYV
                     AGLESVTVIHGIGTGVLKAGLQDILRRNRHVKSQRGGQYGEGGAGVTIVKLK"
     gene            57509..58960
                     /locus_tag="PC512_000739"
     CDS             57509..58960
                     /locus_tag="PC512_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-histidine dipeptidase"
                     /protein_id="HDF2440509.1"
                     /translation="MGNVLEGLKPESVFKNFEKISQIPRGSGNEKGISDFLLSFGKNL
                     GLETIQDESLNIIIRKPATKGYENCPGVVLQGHMDMVCEKEKNVEHDFLKDPIKLRID
                     GDMIYATGTTLGADNGIAVAMGMAILEDNTLEHPALEVLVTVNEEDGMNGADALDPSL
                     IKGQYILNMDSEEEGYLLVSCAGGKTCVVSLPVEYKEVKGDKQGLLVEVTGLLGGHSG
                     MEIVLQRANANKAIARVLSVLNVDYELASVDGGTKHNAIPREAKCVIAVNKADVESAK
                     KQINDILTAFKHEFTTSDPGMTYSVAETSVDKVLTKDCKEKVVQMSCLTPHGVQSVSL
                     DIEGLVESSTNFAIIETKESTIEFLTSVRSSVMSIRDEIADRIRLLAQALGANYDLIA
                     QYPAWEFKKGSKLEKICSETYEKLTGKVPTVMALHAGLECGLLLDKLPHAEAISIGPD
                     MFDVHTPNEHVSIPSVANVWDYVIEILKSMNQY"
     gene            complement(59164..61677)
                     /locus_tag="PC512_000740"
     CDS             complement(59164..61677)
                     /locus_tag="PC512_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HDF2440510.1"
                     /translation="MEDCVVNLKKLLLLIIVITSIFTSCIFSFGINAIGNDNRTIRVA
                     YPIQKGLTEIDEQGNYFGYTYEYLLEIAQYTGWNYEFVQVPGEINESITKLMKMLENG
                     EIDIMGGMLYNEPMQKIYNYAGNNYGVANTVLQALYENTDIDNIMSSQDVKKIRIAVI
                     ENSDTRLKELDEYCKMNLMSPELVYCKTNDEQLEALKSGKADVLLNVSMNPIEGVRTV
                     AKFSSKPFYFITPKGSTNLTQKLNSAINNIEQKDPYFSTTLYEKYFTPENNQMFLSDE
                     ETNYIKETEKLKVGVLLNKPPFQNIDKDTGELRGISIDLLNHICDKTGLEFELVPVKS
                     QEDLENMTKKREIDIVAGMIYDYEYSREHNIAMSRPFLSTQYTMMINNKLNENSLDGK
                     RVALAKGINYYGQFEENIVWYDNLEECIEAVNKGYADYTYGEGYSMQYYMNQPKYKNV
                     RLVPQTYKAKSICFGIIKKDKQELLNIFNKAIISISSEKMQSIVYQNTTYRQDFSLLY
                     IMQQNPIETIFIVASLLICIIGFMAFGLHTRTSMNEKISLELKKHTQLYEMTSEYFFE
                     YDYKQDKLIISMPEKGIETYYGLDKNDKESENGNIENERDKIRKEYNKKFFDVIKSQE
                     NGTTEMYSIMLDDTFHWIRVTSKIIYNDRKIPMYVIGKICNIDSEKEEKNRLLDKAQR
                     DSLTNIYNAAYIRKLTSQNLLNLSTEKNGALLIIDIDYFKSINDTYGHLLGDKVLIDV
                     AKALDESFAKNDIVGRLGGDEFSVYINDIINKEELINKCNDVYNHIHLIKLPNGESLS
                     ISMGVVIAKPGQEYDELYQIADNALYDSKRQGRNRFKIV"
     gene            complement(61900..62721)
                     /locus_tag="PC512_000741"
     CDS             complement(61900..62721)
                     /locus_tag="PC512_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF2440511.1"
                     /translation="MIDINLEKCVGCGMCESDCLVNAIKVKDDKAKVKNILCINCGHC
                     MAICPTDAIEMQGFDKNEVIEYNRESFELEPEKLLNFIKFRRSIRQYKDIEVEEEKIK
                     NIVEAGRYTPTGGNRQPIRYILVKEKLKEVKELAIQGLYNLALDTDDNDPVRSIYKNT
                     FKKMYKRYKENGNDSLFYDAPLLMVVVGDMSLGGSAYVDGGLAASNMELMAYSQGLGI
                     CYNGFFVMASNVEPKIKELLGMSENEAVITSFILGYPDVKYKRTVNRNTAKFEVR"
     gene            complement(63239..63715)
                     /locus_tag="PC512_000742"
     CDS             complement(63239..63715)
                     /locus_tag="PC512_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HDF2440512.1"
                     /translation="MKLTTICYIEKDDKTLMLYRNKKKDDIHEGKYVGVGGKFEQGET
                     PEECVIREVKEETGLTLKSLSYKGLITFPKFKDEEDWYMFLYFSDEFEGELSEKDLND
                     CKEGNLIWVDNDKIFDLNMWEGDRLFLNWAKTGNIFSAKIVYDNGKLKDYNVSFLD"
     gene            complement(63750..64328)
                     /locus_tag="PC512_000743"
     CDS             complement(63750..64328)
                     /locus_tag="PC512_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HDF2440513.1"
                     /translation="MREEALEILFKYLETDRMRKHCYAVEAVMRELAKRLEPEKEEEW
                     AVAGLLHDLDSDIVGRKPGEICEGHATTTVELLKKENFGNEEMYRAILGHHDGMGVTR
                     TSLMEKAIYAADPITGFITAIALVYPDKKLTSVKTKSVIKRMKETRFASNVNRDAMRS
                     IEDIGIPFDEFAELSLNAMKNISDVLESAENN"
     gene            complement(64432..67032)
                     /locus_tag="PC512_000744"
     CDS             complement(64432..67032)
                     /locus_tag="PC512_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HDF2440514.1"
                     /translation="MKKIELLAPVGSFDSLKAAVQNGANAVYLGGKDFSARASANNFD
                     RNELIEAVKYSHIRGVQVFVTVNTLIKQYEIEDFVEYVKFLYDIDIDALIVQDIGMAR
                     LIKKLLPDFELHASTQMVAHSLEDVKYLQSVGFDRVVLARELNVDEIKWICENTTVDI
                     EVFVHGALCVCYSGQCLMSSMIGNRSGNRGRCAQPCRQKYELIDINTGEVVKSNGDYL
                     LSPRDLSTIEDLDKIIEAGVLSLKIEGRMKKPEYVATVVSGYREAINEFVDKKKISIS
                     EEIINNLYTIFNRKFTKGYILGEVGKDIMNSNRPNNQGLYIGKVLDYNRKNKRLRVML
                     ENTLKKGDGINLGGGTIGRIIKDGEITTIAHKGDLIELDFVGEAKRNQLIYKTSDSEL
                     MDRVQATFQQDKEFIKTNIRAKVSIKLGKKPELFISDFCGNKSVVEGDKIVEKAIKVA
                     LSKEKIETQIQKLGNTPYKLKEIEIDLDEGVSMPISVLNQMRRDCIELLDEERIKIKD
                     RKFKKNRLKYQPNRVNKQKKLDTAPKIRVKVKNLEQLEAVLNYNVDLIYYEDINTLSK
                     ALQMVSSISIDSNISIDSSISMDLDTSSSLGTPKELMGSNTNNIDTLSNTSKIDTLNK
                     NHSNTAVTDKKLIYSAPRIVRNKEYKQFEILDNIKGINKVQIGNWGSMEYFKKKDLNI
                     DCYLNVFNSESINHFKEEGASTVCLSQELNLNEIKQTLKYTDVEIEAVIYGYAPMMVT
                     EYCPMGVVVRDCKKDKRVAKCKESSYALRDFTDASYRITQDIFCRSTIYNSKVTCMLD
                     NLYELEEIGIDVFRIDFTVEDSEMVKKVIEAHIEVLSNNYKLGKKATDLYKKLDEIGT
                     VAGHYYKGVE"
     gene            complement(67602..68285)
                     /locus_tag="PC512_000745"
     CDS             complement(67602..68285)
                     /locus_tag="PC512_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HDF2440515.1"
                     /translation="MTSKSQMSESFFLCSLLAITGGFLDIYTYVVRGKVFANAQTGNI
                     VLFGLNIAEGNVKESFYYLIPILAFMLGVFIAEKIRKYFTNNKTKIHWRQVIIIIEMI
                     TILIVSFIPRGRFNMFVNVAISFICSMQVESFRKVNGNSFATTMCTGNLRSATETLFH
                     YIHTKNIFMIKKSLQYYAVIIFFISGAILGTFFTKIFVEKSILICFFILAVVFGIMFI
                     NKDDSFNEN"
     gene            complement(68461..69051)
                     /gene="zapA"
                     /locus_tag="PC512_000746"
     CDS             complement(68461..69051)
                     /gene="zapA"
                     /locus_tag="PC512_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HDF2440516.1"
                     /translation="MNKVMVKIHGAEYPMVGDKSEKFMISIADFVDKEMDKITRQNPK
                     LSLSVAAILTALNISDLLFECSDENEKLIKANEELSKKVGASNEELQLEIKSLKLTIA
                     EKEAENREAETKMKELIEIIENKKQEIFELSNTTEGSRAELDAYKNKIEELSTQLEEA
                     NERATIAENLASEFQNKAYDLQLKCTGLNNDAKNVE"
     gene            complement(69076..71469)
                     /locus_tag="PC512_000747"
     CDS             complement(69076..71469)
                     /locus_tag="PC512_000747"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HDF2440517.1"
                     /translation="MLVSLKWLRDYVDIDMDVKEFADKMTMTGTKVETIDYYGEEIEN
                     ILVGKILEIKQHPNADKLVVTKVDIGDKVVQIVTGATNISEGDYIPVAVNGSKLPGGV
                     EIKQTDFRGELSDGMMCSAAELGIDEHYIEEYKRGGIYILDHEDSYELGKDIKDVLGL
                     KDALIDFELTSNRPDCKCMMGIAREAAATIGTKVKYPEIEVKESDEEIDFKVEIDNPD
                     LCRRYVARMVTDVKIEPSPYWMQRRLTEAGVRPISNIVDITNFVMLELGQPLHAFDIN
                     QVETGRIVVRNAKDGEKLVTLDDVERTLDKDMLVITNGEKSLGLAGVMGGANSEITSN
                     TKTVLFESANFKPENIRMTAKKVGIRSEASSRNEKDLDPNLAEIAANRAAQLVEMLGA
                     GKVLKGVVDVYPNKPEPKKLVVNPQRINHLLGVDVPMEQFVGILESLEFKCNLVANDK
                     LEIDVPSFRTDMEQEADVWEEIARIYGFENIPSVQLEGNTTAGIKTSKQKFMDALKDN
                     STAVGLNEILTYSFVSPKGVDKIRVPEGNAKRNFVKLLNPLGEETSVMRTTLIPNMLD
                     VLSTNVSHKIEEVSAFECGHIFIPQDSELPKEENRMCVGMYGKDVDFFALKGTIETIL
                     VNVGFKGYEIEPQDNNTTFHPGRCAKIVYNNKYVGTLGELHPDVIENYNLGQRVYVAE
                     IDIDFVFDNSDRTKNYVPLPKYPSTSRDIALIVKDDVFVKQIEDIIKENGQGLVESYK
                     LFDVYKGSQIEAGYKSIAYSITYRSKDKTLTDEDVAKVHDKILSELSEKLNANLRSN"
     gene            complement(71486..72505)
                     /gene="pheS"
                     /locus_tag="PC512_000748"
     CDS             complement(71486..72505)
                     /gene="pheS"
                     /locus_tag="PC512_000748"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HDF2440518.1"
                     /translation="MQEKLLALREAALAEIKEAQSIESVESLRVKYLGKKGEITAILK
                     EMGKLSAEERPVVGKVANEVRENIELSINSKKEEINAIEKERKLKEEVIDVTQPGKVL
                     KVGKKHPITQIIDEVTDIFIGMGFSIAEGPEVETVENNFDALNAPKDHPSRDMSDTFY
                     INDGVLLRTQTSPVQVRTMRSQELPIKVIAPGRCFRSDSPDATHSPMFHQIEGLVVGK
                     DVTMAEFKGTMDIFVEKLFGSDIKTKFRPHNFPFTEPSAEVDVTCFKCGGKGCPMCKY
                     EGWIEILGSGMVHPNVLRNCGIDPEVYSGFAFGVGVERLAMLKYEIDDIRLLFENDMR
                     FLNQF"
     misc_binding    complement(72555..72789)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
BASE COUNT        22635 a        13672 c         8006 g        28553 t
ORIGIN      
        1 aaatatatta tattatacat atacttattt ttactataaa agttaaattt ataagcttac
       61 ttgttataaa aataactttt ataatttatt tcaaaaaaaa tattgatttt tgtgtcgcat
      121 tttgttataa taaattaagg ttatccccct ggtaacccta gttagttaat atatctattc
      181 ccaataccct ttcataagga tatattttat atttattaaa aatcggatta gtaacggaaa
      241 ttaattcggt ggaaaaaaag agcttacccc gagctctttt tttttctgca aaaaatcgta
      301 aaaataaagt taatattaat ataactttaa ttttaaaatt aatattaacc atcactaaaa
      361 aaggatgtat tgaatttcta atatcaataa catccttttt atatattata gcacttttgc
      421 taaaaacgct tttgttcttt catgttttgg atttccgaaa acttcttctg gagtattatc
      481 ttcaagtata cttcctccat ctataaaaat aactctatct gcaacttcct tagcaaatcc
      541 catctcatga gttacaattg ccattgtcat accttcttta gcaagttctt ttataacatc
      601 caaaacttcg tttaccattt ctgggtcaag agcagatgtt ggctcatcaa acaacatcat
      661 atctggttcc atagcaagtg ctctagctat tgctattctt tgcttttgtc ctccagataa
      721 ttgtgatgga tatgaatctt ttttatctaa aagaccaact ctactcaaca aaatttctgc
      781 ttttttttct gcttcttcct tagtcatctt ttttaattta attggtgcta atgttatatt
      841 atctaaaata gtcttatgtg ggaataaatt aaagttctga aacaccatac ctatattttg
      901 tctaacctca tcaatattag tttttttatc gaccaaattt tttccttcaa atattatttc
      961 tccacctgta ggtatttcta gtaaattcat acatctaaga agtgtacttt taccagaacc
     1021 acttggacct actataacca ttatttcgcc tttagcgatt tctaagtcta tattttttaa
     1081 tacatttaaa tctccaaaag atttacttaa attttttatt gtaatcatat tatcactttc
     1141 ctttttacta ttctatgttt tccctaaatg ctaaacatgc tctcatctag ttagacacag
     1201 atagtttctt ttctaataat ccaactaatc ttgatagagt aaatgttata acaaagtaaa
     1261 ttgctgctgc tactattaat ggctctaatg ctctaaatgc tgcatttttt actatatcag
     1321 cagtacgcat tatctcaaca actcctatta cagatattat tgaagattct tttacaagtg
     1381 taataaactc atttgctaat gaaggtaata tattttttat agcttgaggt attattatat
     1441 atctcatagt tgaccaataa tttaatccta atgatctact tgcttccatt tgtccattat
     1501 caactgattg tatacctgat ctaagtatct ctgccacgta tgcaccagag tttactgata
     1561 atgcaaatgc actagctata aattcacttg gtataccaaa caacataggg aatcttattc
     1621 ctaattgagg taaaccaaac catactatat atatctgtac taataatggt gtccctctta
     1681 aaacctcaat atagattgat gatattgctc ttaatacttt gctctttgat atttttgcca
     1741 tacagataat tatacctatt ataaatccaa agcataatgc cacaagagaa attgatactg
     1801 tcacacctgt tccttccaaa aaagaagtcc caaatctact taaaaaacta aaatctaaac
     1861 tcataatttc atctcccaca taactttctt actaatttga agcagcttca gtagatgctt
     1921 catttaaaaa ttcttctatc ttcttgccat cttgtaattc ttttatcttt ttgtttaata
     1981 attctataaa atctttgtta ttgtcagatt ttttgattgc tgctgccata ccttctgtta
     2041 catctttccc aacttcagta tttgccattt ttattccatc atatttttta acatttatta
     2101 aagaaactgc ttcattagta acaactgcat ctatgtttcc attttttaat tctgtaatta
     2161 aatcaggtat tgctttcaaa gattttgtag ttgtcatttt taaagtgtta actacatatt
     2221 cttcttggat acttcctgct tgaactccaa ctctaagttt ctttaaatca tcttcagttt
     2281 ttactttgtc tatatctgca tctttaacta taactgcatt tctacttaaa taatataatt
     2341 ctgaaaaatc aacactcttt tctctctctg gtgttggaga catacctgca agaacaatat
     2401 caacttggtc tgcatttaaa gcacctatta atccatcaaa tgacatatcc ttaatttcaa
     2461 cctttacacc aagctctttt gcaaattctt cagccaacat tatatcgaat ccttttattg
     2521 aatcttttcc atctactacc ttatgaaatt caaatggagg aaattctgca ctagtaccaa
     2581 caactaattt tccattgtct tttatttgtt ctaactttgt tttttctcct ccaccactac
     2641 atcctactag cgataatgtc aatcctaata ctaatcctaa acttaataat tttttaaata
     2701 ctttcatttt aactacccct ctcttttaat tataatttcc ctcagatttt aatacttaaa
     2761 tgtttcgagt tacaaaaaaa gtctctcagt ctttaatgac taagagacga ctttaccgcg
     2821 ttaccactct tattgataaa tacttatatt actttcaaaa tttgtgactg ttagctttta
     2881 agctgtatgg atatttttat tttaaaatca aaaaagtccc ttagctttac agctaagaga
     2941 cgaattatat ccgcgttacc actctttttg ataagtaagt acttatcctc tcaatccctt
     3001 aaggcgggta aaccaattat catactaaag tttctgataa tctcctccag agctctcttc
     3061 acatagactt cattgttagg cttacaccaa cccctaactc gctgtaaatc catatatgct
     3121 actttctcta tcattggatt tgtttcctta aattgttaat acaattgtac ttccttataa
     3181 tatttttgtc aataagtttt ttattttttt aataattttt acttgtaaat tatctaaata
     3241 ctactgttta tatttattga tattatttgt gtaattataa atagtatatt tcatattttt
     3301 agctatttct taaataatac taaataatat ctttcacatt gttgcttttc tttaataata
     3361 ctaaataata ttttccacat tgttgctttt tctaaacaac tataaataat atattaaacc
     3421 cttatttctt tttctaataa gttaaataat acattttaca catatctatt tgtcttgcac
     3481 ataataaata atacattata tttctatcta aatttagatt ctaaattaaa tagtataaat
     3541 tatattcttc aataaacaag ttttcaaatc caagattcgc tctctatctt taaactttat
     3601 tgtaaacata attccatctt ttttaattat ttctccttca tgaaattttt tatggtatac
     3661 cttatcccct acaccaatac tgtcaatttc ttttttcgtt ggagatttta tatcattaat
     3721 aaataatgat ttatcaactt tcttaccata cttatttaaa gtagagctta tacataactt
     3781 ttcttcagct cttgtaatag caacatacat aagtcttctt tcttcttcta attgttcttc
     3841 ttttttctct tccttacaaa tatcatatga tttttcatga ggtattgttc cttcatttac
     3901 acctataata taaacatttc taaattctaa tccttttgca ctatgcatag ttgtaaatat
     3961 gacaccctca gtctgcttat tcttgttatt ttccgttaac tcagtcttta ctctatcaat
     4021 atgctctaaa aactctgtaa cagtattaaa attagttgct gaactctcaa gttcatttaa
     4081 tatctctaca agtccattag tctttatctt tctgttgcta caataatcta aaacatatct
     4141 atcataatca agactagttc taatataaga tattgcattt ttaggattta aagtatttaa
     4201 ataacttaaa tctatttcca aatcatttat tgttttaact tgtttaggat gaagattaca
     4261 cttatttatt aatgctgtta taaagtcttt ttcatcctta accatattta tactgtcttt
     4321 ggatatatat ctaaaaggct tgtttataat tctcaaccaa tctttatttg attttggatt
     4381 aatacctatt cttaaatagg ctagtatatc ttgacttgcc caatggtcat atattgtaat
     4441 tactgagtct tttactacaa atggaatcct catatccata aatacatcta ctaatgctct
     4501 tgactgtata ttagttctat aaattactgc aaaatctgaa tactctacat aatctttttg
     4561 tatttcgtca attatttccc tggcaatata taaggcttct tcctctgaat catgtggaga
     4621 aatataggta acacttcctc catccccctg actacactta atgatttttt catatctatt
     4681 tttatttttg tcgataagtc tatttgcagt atgcactatc tcacttttag acctgtaatt
     4741 tatatctaat attatttttt tagtattatt aaagtattgt tcaaattcaa gcaaaaaatc
     4801 tggtctagca cctctaaatc catatatact ttggtcttca tctccaactg caaatatatt
     4861 gtttaatggg ctacaaatta actttaaaac ttcaaactgt actttattta tatcttgaaa
     4921 ttcatctatc aatatatatt tatacacatt tctaaccatt tctagtgcag acttattgtt
     4981 caaaagtaaa taataagttc ttataagcat atcatcaaaa tctattttat taactttaga
     5041 tttttgttct tcgtataagt tgtatacttt taaaaactca tcttttgtta atacttctga
     5101 attaaattca tttttatcca taagttcatt ttttacatag gaaatttcat ttataacttg
     5161 tcctatattc tcatcatcat cagcattctc tatatttaaa ctttttagga ttgccttgat
     5221 tgtcattcgc tttgactttt catcaaatat actgtctaag ttgtatcttt caaagtatct
     5281 tagaatttta aaaaatacag agtgaaaagt accataggtt accttattaa gtcttatgtc
     5341 atcacttaaa ttcaaagctc tatttttcat ttctattgaa gatgccttgg taaaacttat
     5401 tgccaagatt cttgttggtg ctatgttttt gtttacaacc atattggcta ttctatatgt
     5461 aattactctg gtcttacctg aaccaggccc tgcaagtatc atgcaaggcc catctatatg
     5521 ctcaactgct tctaattgat tttcatttaa ctttcttata tctatatttg ttgtgattat
     5581 tagctccacc accttgattt ataattatat tattttcttt ttaattataa actaaaagtt
     5641 cataaaaata aatttaattt ttcctctatt aaaccacatc attcctattt tcatgacata
     5701 tcttgagttc ttttttaatt ttgtcgctta tatcttcagg tataaatgat ggtttactaa
     5761 tatagtagcc ttgcatataa tctactccaa gattaattag tgtttccatt tcaccttttg
     5821 tttctacacc ttctgctatc actttaatat ttctttcgtt agaatatgag ataagatttt
     5881 ttaatatttt ctgtctgttt tcatctttat caatacctct tacaatagac atatcaatct
     5941 ttacatagtc tggcattata tataatagta cagcatctcc gttgtaacct gtcccaaaat
     6001 catctaaagc aatttctata ttccaatggt ctatatatgc tttctttttt tcaataaaat
     6061 cttcattaat cttatcattc tctgttattt ctagtactac tctatttaaa tattcaccat
     6121 ataaatcttc aatttcctca aaatctactt ttgacaaatt attattagga atagaattta
     6181 agaacaattt gcaatcgcca aatttttctt tgtatttttt aaatgattta agtgctttaa
     6241 accatgtaat acgctcaatt tgatataatt tagactgtga acgagctaat ctaatgacat
     6301 ctattggtga actaaaagtt tttattttag gtctcataag tgcttcatat gcaaatactt
     6361 tacctttaca atctacaata ggctgaaatg catactcaac taattgacca tcaattaact
     6421 tgtttaattc ttctctatta ctcaataaga atgaatcctt attatatata ttaatatcaa
     6481 attcactaac ttcacccttg attgtatttt taatttgata catagcaaaa tctgcgtatc
     6541 tcattaattc atcatagttg gttgagtcat cagggtacca ggaaattcct gctgatgccc
     6601 ttattttaaa ttctgttcca tcatgaagtt ttaataaggt attattcatc tgtttcttaa
     6661 cagaattaat aatatctctt atactatctt tgctttcata tccatatata aatacataaa
     6721 actcatcacc tgaaagtcta gatactatac cattccatga tataaacttc ttaagtatgt
     6781 ctgcagcaca cctaatatat tcatcaccag catcatgtcc atatgtatca ttaatatatt
     6841 ttagattatc taaatcccac ataataaatg ctgctatctt aagttcatct ttattcttaa
     6901 atttttcttg tatctgtgaa tgaaaagctc tcctatttaa aagattcgtt aaaatatcaa
     6961 aatctctttc atattctatc ttccttttct caataaattc ttttgtgaca tcaacaacaa
     7021 caccaagaac ctttagctca tcttcaaaga tattcattct tatccactta agttttttat
     7081 ctttagattc aaacttatat atatatgtat tttctgtttc ataactttct tgcaaatatt
     7141 tatctagtcc ccttaatttt ttcaggaact tatttttttc catatatcca tattcttcaa
     7201 atttgatttc agtagtaaac acgctaaaaa attcttttgt acaaaaaaca ttctctgcgt
     7261 ttttgtataa ctcaaaagcc ccaattggca tatctaccat ttcaataatc tgtgataatt
     7321 ttgacgaaga atctgcaaca tttgcactga gcaactctat agctgaagat aattcatcta
     7381 tttcagatat atttatctta tcaagattta ctggttttga tggattactg tttctaactt
     7441 tgttggctaa aagaacaatt ggttttgtaa ataatcttga tgcaatgtaa atacctatta
     7501 gacctattaa taaagaaatt gctatagata ttataactaa tttctctacc ctttttgaaa
     7561 atgacaaaag acttttttct tcaataatac ccaaaagagc ccaacgttca ttttcaaatg
     7621 gagtattgga gttatataaa tccaagtatt gtacactagc ataaatgttg ccattaccac
     7681 attcattatc tttattttta atcttatata tatttttata cgattccttc tgctctaaat
     7741 tagaatgtaa accatcccaa aatttttctt ttaatgagta tccatttgaa attacatttt
     7801 caaaggccat atcattattt ctatctacac ctaaaatata attacccttt ttatttccat
     7861 ttatctctga gtatggaagt aattctctta aataatttac acttaaatct attccaagta
     7921 ctccatatac agttccatct tcataaataa ggggaactgt atatgtcata agcctatcac
     7981 ctgcatttgt caataaaaac ttacttcccc agtatcctaa attagaactt gatacatttg
     8041 gattatcaat tgcagctcta aatggtttat aaaaaaaatc atctccatct tgctcatttt
     8101 cacttttaaa tgaaaactta ggttcccaat aactgtccat agatattcca aaacttcttg
     8161 ctatatctga tgaacctctc tcaattaaca aatcagaatt atcatttgga ttaaacttag
     8221 ggtctaaatc ccttatatac aatcctgtcc tacttatttc acctttacta tctattgact
     8281 tatcgttaat atttttgtca cttaggatta taaaagctcc tgtaacagaa ttttttctca
     8341 aaagatatat taaatcattt gatatgcttt ttataatatc tttgttaatt tcttcattgt
     8401 tgcctacatc ctcaattaag gcattttttt catttaatac tttttttaca gaggaattaa
     8461 ttgtagcttc cgtttcactt gtatttgacc atctttgtaa catttcattt tgtatataat
     8521 ttttacgatt aattactctt tcatttaaga tgtcaaacga attatcattt aatttcttaa
     8581 tagttcctcc ccataaaatt gtggcacaaa ataaacttgt ttgaattagc ataacaataa
     8641 ttaggggaaa tatcatcttt ttcattattg aattgttttt tcttagattg ttttccatac
     8701 ccattccacc tatacctttg tgctcgtcaa cacactaact gccaattcat ctattttttt
     8761 atagcatttt caagctcagc cttaaaactt tcaaaccaag ttttaaaatt tttatcatta
     8821 ttaaattgtg ctactgcatc cttcttagaa gttccacttt ttactaattc atttatttta
     8881 tttgaatctt ctttagcttt atcaagcatt gaatattcaa gtatttgtct agctttagtt
     8941 ccaccatcaa atgctttatt agtatataaa ttacaactgt taatctgttc aatagatgag
     9001 gctattgaac cttcaacttt atcagataaa ctcaaattat ctttcttcat aacttctttt
     9061 ataacatcca aatcattcgt ttttttcttt actggtaagt atccagaagc aatagagaat
     9121 tttatattag gttctttatc tgtaaaccat tttaaaaatt ctactgatgc atattcttct
     9181 tctttagtag attttgttac agccattcct gcaccttgtt gtacagcata ttttccttct
     9241 cctttaaaac gtggtgcttg aaaaacagat gtttcaatat tataactctc attatcattt
     9301 agcattactc tatctggaaa gtatgctgct cctgaactag aacctacaag agctaatata
     9361 tcacctgttt ttgcatcatc agaacgaaac ttaccataag aagcaaaata tccatttata
     9421 tatggtacat agaaattatc ccatagtttt ttcataactt tttcatcaat atttagtgta
     9481 actttaccat ctttaacaga aaaaatttct actcctagtt gtttacttcc tataataata
     9541 taatttgcta aagcatctct tccaaaaaat gctttaccat cattaggctc tttcgttaaa
     9601 ctatctgtcc attcataata tttttttgat gtctctacta atccttcaat tgtttttata
     9661 tcatttatat ttgaatttgt agcttttgca aatttatccc aatcagtttt atttaacatc
     9721 aaaatttcag ttgattttgc aattgggaaa agtttaaact catccttaga atttattctg
     9781 ccttcttcta catattcgtc tatgtattca tttaattctt ctttacttat gtacttatcc
     9841 atatctacta gtaaccctaa tttatccatt tcatatgcag tatctgagta tgctgcaaat
     9901 atatttggta catcttcaga accaactttt ttatttgcag aatctaaaac tttctctgat
     9961 aaatcaacta cattaccttg actgaatgct tcaacaataa ttcctttttc agcacctaca
    10021 gtgtcattaa attccttaac aagcttatca aaagccattt tctgctgtcc attataataa
    10081 tgccaaattt gtattgatgt cggattttct gggtctaact tataattatc ttccttcttt
    10141 aaactacatc ctgtaagtaa taaaacaatc attgatgtga taattaattt tgcaaactta
    10201 cacctattca taaaatctac tccttcaaat tataaaattt ataatagcat taaaactgta
    10261 acttcactat ttatattaat tatagaacgt ttattgatat atttaaacag gatttacaac
    10321 atatttaaaa gcaattaaga aacatactat tacaaatata gaaaataaag cttttacata
    10381 atttttattt ctaaatgcac caaatgacac caatccttgt tgaatagcta ctgtaattac
    10441 taaaagtatc attattatat taagttgaac cagtttaaat aagtaaagca atgaaaacac
    10501 tactagaagt acacataata caatactaga tttattaata atatcatcaa tcttatctac
    10561 tttcttagat tgcttattaa ttttatttaa tttttcttta tttaaattct caactttttt
    10621 attatacctt tctcttgttt tatctttata tttagtattt ttatttttat ttcccattta
    10681 ttttccatcc tctataaatt ttttaattga gcttatacat tatttaaata ttatatattt
    10741 aagataccat atattcctac aaaaaggtaa cttactatgt atctattttt gattttcgca
    10801 taaaaaagcc atctccttta gaattaattc tgtattgaga cagctaattt aactatttat
    10861 cctttgaaac attttctaca ttatcatatt tactatcaac taaaactata tcaactcttc
    10921 tattttttga cctaccttct tcagatgaat tttctgctat tggtctaaac tcaccatatc
    10981 ctacagcaga taatttatct ggtgctatac ctgcattgtc aataagaagt tgaacaacat
    11041 tggttgctct cataactgat aaatcccaat ttgacttaaa ctctgaattt tttatagaca
    11101 tattgtctgt atggccttct actctcatgt aactattcat ttcatttaac atcttaccta
    11161 tttgaataat cttatctcta gaattatcct tcacaatagc tttccctgta tcaaatagta
    11221 ttgtatcttt aaggcttatt actaatcctc tatcttgaac tcttaatgat actgaattag
    11281 ccataccatt ttcgtttaaa tacttctgaa tttcttcacc aattttttta aacttagcat
    11341 tttgtaaagt atctaaatca ttacttcctg gttcaactac tggttctatc ttgctattac
    11401 caccttcaat aactccagaa gaaccaccaa aagcagaatt tagagattga gataattgtt
    11461 tatatttctc cgcatcaaca ttactcatag aatacattat tacaaagaaa atcataagta
    11521 atgttatgag gtctgaataa gttaaaagcc atcgctcatt gttttcttct ttttcatctt
    11581 catcatacaa cataaacatt ccatcctttt atattattca gctctaccac caatttcttc
    11641 aagttcaatt agttcttttg aatttaaaaa tatttttaat ttttctgtca ttaaattaga
    11701 attatcaccc tcaagtatgg ataatattgc ttctatcacc aaaagtcttt cacttacttc
    11761 ttgttgattt atagccttaa gttttgatgc tattggtaac catattaaat tggcagaacc
    11821 aacaccatac aaagtagcca aaaatgcaac agaaatttga ggtcctaatg catctggatt
    11881 acttgaaaga ttacctaaaa tatgtactaa tcccataact gtacctatta tccccagtgt
    11941 aggtgcatat ccacctgctg aatcaaaaat tgctattcct tctttatgtc gttttgatgt
    12001 tatctgtatc tgtgattcca atatatttct tatagtaact gcatccactc catctaccat
    12061 aagttcaagc ccttttctaa taaaagggtc taattcatca ttctcactta tttctttgtc
    12121 aatactaaga agcccctctt tcctagcctt tgttgcaatt tctttgaaat agattatatt
    12181 ttctatgtta ttaggctttt tatttttaaa agttaataac attatcttta tagacttttt
    12241 aaacacaggg aatggagtcg aagctccaac agctcctata gttccaccaa acacaacaag
    12301 tgctgatgaa aatacaaata atgctccaac atgtccccca tcaataacaa aagcaactac
    12361 caaagatgct atccccacta tgaaaaaaat taaagttgtc atctattccc tcctttcttt
    12421 agttatacat atctaatcat ttatgacatt ataaaaagac tatctttaat aaaaatagcc
    12481 tttaataatt ggcggagaag gagggattcg aaccctcgca ccggttaccc agcctaatcc
    12541 cttagcaggg gatcctcttg agccacttga gtacttctcc atatctctat actagtaaat
    12601 tatataataa aatcatattt tagtcaattg ttttataaaa tttgagttat tttgaattat
    12661 taaacatcta tttttacttt tttgcttaaa tgtaagtttt aaatatggta aaattatctt
    12721 gcataacact tataatatta tttgataaat atacatacat taacaaatat acctaaactc
    12781 tgacttaatt gtaagttatg ccaaaactaa aataatacta gtccaaggag gatattttat
    12841 gttaccacag gaaagatatg agaagatttt aagtattctc aaatcagata atataattaa
    12901 aataaatgac atagttcaaa tgtttgatat atcaatagaa actgcacgaa gagatttagc
    12961 ccatatggag agtatcggtc ttttaaaaag agtttatggt ggtgctatac cagttatagc
    13021 aagtagcgta gaacttaact atgttaaaag aaaaaaaata aactcaaacg ataaaaaaca
    13081 gattgctatt aaatgtagtg agtttataaa tacaaatgat actattttta tggatactgg
    13141 aactactgta cttgaagttt caaaaaattt gaaagataaa aagaatctaa ctgtaataac
    13201 caactcaatt ttagttgcaa acgagcttat gaatactaat ataaaagtat atgtgcttgg
    13261 gggctatctt agagaaactg aaggttcttt ttctggtccg cttacactgt cagctattga
    13321 acaatttaat gttgataaag ctattttagg cgctggaggt atcactcttg aaaatggaat
    13381 ctctgactat cacttagaag aagcacttgt tagaaaaaaa atgattgaaa ggtctagaaa
    13441 atctatagta gttgtcgaac ctcctaagtt tggtataaat tcatttgcat cagtagctcc
    13501 tatagaacat atagatacta ttattacctc tgctagtata gaccataata taataataga
    13561 gttttctcaa aaaggaatac ctttagtcat agctgataat tagcttatat gattgatttt
    13621 tagttccttg atgtaataaa ttaaaattaa ggagccaaat aattatttat ttagctccat
    13681 ttatgtctaa actatacttt atattttaat tatgtaacta ctttcagtta gcttatcatt
    13741 tttagttatt tgattgccat tttatttaat ttataagttt tagttattcg attatttttt
    13801 aattgtctgt ctttttaatt tatttttagt tatttaaact cctactttaa aataatttaa
    13861 atttgactta agtattgttt attctacact gcatctttct tcattttaat actttgttct
    13921 tcttccaagg ttaaatcttt tgtcataagt atagcaagtg caattgccaa tactcctcca
    13981 accaattttc caattacaac aggtgtaatc atctctggaa ctactcctgc tgtaaatcct
    14041 aaatggtccc ccaaagctgc tgtagcacaa accagccaag cagtatttac tactttcccc
    14101 tttggactca tatctttcat cattttatat actggaatac tattggctaa agtaaaaact
    14161 aatcctgctg cactagtggc atccatacct aattttccac ccactattgt aagtggttta
    14221 ttaagaactt taactaataa atgtaatatt ggaaaagtac ctaataacac gattgcaata
    14281 cttccaatta cttgaatacc ttctcttata ggtgtcatgc cttttataag tactatacct
    14341 gttatttctt gaaatgctgc tgctcccaaa cctatcgtta tcaatataga tataaatttt
    14401 ccaaaaacta atgacccatt tatcataagc gtagaattaa attttaaacc tactgccaat
    14461 attactgcca atattatcac tggtatcata tttataatta ccattgataa gttaaatcct
    14521 gctattaatc ctcctataat acctccaaaa ggtattgtta tcaagcctat cagtaaccct
    14581 tttgcaaaga atggtctgtc ttcatattct ataagaccta gtcctactgg aattgaaaat
    14641 actaatgtac atccaagcat ggatgacaca accaatcctg caagcattcc tgcctcttta
    14701 ttgtgtgcaa gttccatagc caatggatac cctcccatat cattcgctaa aatagttgca
    14761 aacatagatg ggtcagctcc acagagattg aagattggta ttattatagg acctagtaca
    14821 tctgaaatta ctggagctaa acaaactata ccaaccattc ctaaagccaa tggacccatt
    14881 gaattaaacc cttcttcaaa ctgctcgcca agtccaaatt tatttccaat tattctatct
    14941 aacgctccta aaagcactcc cacagccatt atgtataata taattttatc aaagggcatt
    15001 tttaattcct cctatacatg taaaatactc tattgtaact taattagcac acaccttttt
    15061 ggtatcgttt tcccaattca tagctctttt tactgcttgg ttccatccaa gtaatatttc
    15121 ttctcttttt tgagtagtca tatttggaat atattttttg cttattgtaa attcacttct
    15181 aatttcatca atactgttcc agacaccaca agaaagacct gccatatatc ctactccaag
    15241 tactgtcgtc tcaggatttt ctgcaatttc aattggtata cctaatatgt cggattgaaa
    15301 ttgcattgta aagttatttt tagtaattcc accatctact ctcaacattt ttattttttt
    15361 ccctgaggct aagttcatag aatcaacaac atctttgact tgaagtgcaa cagactcaag
    15421 agtcgctctt actatatgct cttttttagt acttcctgtt attccaacca ttgtacctct
    15481 agcatattgg tcccaataag gtgctgctat acctgcaaat gctggtacaa aatatacacc
    15541 tccagtactt gatatggaat ttgccatgtc atcagtttct gaataatttt ttataactcc
    15601 aatgccatct ctaagccatt gtattgcagc acctgctata tacactccac catcataagc
    15661 atatgtaact ttatctccta ttttccaagc aacagttgtc aaaataccat tacctgctat
    15721 atttagttcc tcacctatat tcatatatag gaaacatcct gtaccataag tatttttaac
    15781 cattcctggt tcaaaacatc cattgccaaa taaagctgct ggttggtcta ccattgaagc
    15841 agtaattttt atagaaaccc cacaaaatgc ctccttatct gtagttccaa aatcaccact
    15901 cgtaggcatt atatctgcta aaatacttct aggtactcct ataatgtcaa gcaactctct
    15961 atcccaatcc atatctctta tattaaaaag cattgttctt gctgctgtag atacatcagt
    16021 taaaaaagat tttcctcctg tcattttcca tattaaccaa ctatctaatg ttcctgcaag
    16081 tacttctcca tttttaattt tttcttttac accttttaca ttatctatta cccatttaat
    16141 ttttgtacct gagaaatatg ggtctataat taacccagtc ttatctatta tcttattttc
    16201 taaacctggt atattcttta aattttccac ataatcataa gttctcctgc actgccacac
    16261 aatagcattg taaagtggtt tacctgtatt tttatcccat aacattactg tttcaccttg
    16321 attatctata ccaattcctt ttatatcact ttcattgatt ccattttcaa aagcctgttg
    16381 taatacatta ttactcacag tttttgtatt attccaaatt tctatagggt catgttcaac
    16441 atatccagat tgtggatata tttgagtatg ttccatataa tcgctaaaaa caaactctga
    16501 tttttcgttt atcaatactg ctcttgttcc tgttgttcct tggtcaattg ctaatacata
    16561 tttcacttta aatgtccccc tttattttca gaattaataa attctttttt attttttgaa
    16621 tatataatct attcaagtta tttatatttt atatcatcat gtggatttat gcaatattca
    16681 ttacaatatt ttttgttatt tttaattata gtgattaaaa aagtattttt attgaaatat
    16741 tattgcaata tttattattt tattctataa tctagttaaa ataacacata atattttaat
    16801 atttacacat aatcagtcat tcaaaaattt aaatttaact ttttaaggag gctttacaat
    16861 gaaaaaaaca tatctattca gtcctggacc agtaatggtt acagataaag tcagaaattc
    16921 acttcttcac tatgatatat gccatagagg aaatgagttt atggatttat tcaaagatac
    16981 acaacaaaaa atcaataaac tatataatgc aacttctaat tactactcat taattgtatc
    17041 tggctctgga acatctgtaa atgaatgtgt actatcttct atctttgaca aagaagatgc
    17101 agttctgcta gttagtaatg gtgtttttgg agaaaggcta gaagaaatat tatctactta
    17161 taatgtaaaa acatataaac ctaattttga atgggcagaa tacccggacc tagacatttt
    17221 agaaaaatac ataattgaaa attctgatat aaaagtaatt gctatggtgt tccatgaaac
    17281 tagttcagga atgataaatc cagtccctga actaggaaaa cttgctaaga agtataacaa
    17341 aatatttttt gtagatgcaa taagtgcctc agcaggtgaa tatattgatg tggaagagtt
    17401 taatatagat ataataacag gtgttggtgg caaagctctt ggagcatttc caggttctgc
    17461 atacctttgt gctaaagaga gtattttaca aaatattaaa gaaaatcaat gtaagaatgt
    17521 gtatcttaat ctttataaac actataaagt tgctaaatca tcttctcaaa caccaaatac
    17581 acctaatgtt actttaatat ttgcccttaa tgaagcttta actgagtttt tggaagatga
    17641 cagtaaaata gaaagataca aagaatgttc tgctatttta aggaatggta tggaagaatt
    17701 gggtctaaca tttttacttc cagataagta tatgtctaat acagtaacat ctgtatttct
    17761 acctaaagaa atcaatgtaa atgagtttat attagggcta gaaagggaaa gtggctatgt
    17821 tgtctatcca ggaaaaggta aattcctaga tgctaatata ttccaagtag caaatatggg
    17881 agaaatatat ccagaagatt gttataaatt cttagatatc ttaaaatcaa aattggagat
    17941 aaaaaaagtt atataacagt ttgtttgtaa aatcctacaa tatatcagta taaattaaat
    18001 agactgattt ttttaaattt tcctataata aattatattt tatatttttg tataagggtg
    18061 aactataata tgtaaagttc acccctattt caaatctttt tccttcaata taatcttttt
    18121 cttttaattt attttatatt tttgacataa ttattcttac atttaattgt tttttatttt
    18181 tgacgcaatc gttttttatt cagtcatttt atattcttga tacaatcatt cttacactta
    18241 attatttttt atttttgaca caatcgtttt ttattcagtc atttaatatt ttcaacacaa
    18301 tcattcttac attctattat tgtttgtttt gatacaactg tttttattca gtcattttat
    18361 attctcaaca caattacctt ttcattcaat caaagtaatc tttaagcatt atttttcaag
    18421 ctcatcaaag taattatata cgataacctc acctgtctct ttatctgtag tctttataat
    18481 gcccttagct ccatttacct cttcttttgt aaattcatca tctaacacaa ctttgaattt
    18541 atcttccttt ccataacctt gttgaaattc atctctcaaa attgcatttt tttctgcttt
    18601 tggcttcaac tcaaattcaa ttccagattt catttcatca aaataattta atactacaac
    18661 ctcattattc attttattag ttgtctttat aatcccttta gctccattta cttcttcttt
    18721 tgtaaattca tcatccaatg ttatattaaa tttgtcttct tttccatatt cctcttgaaa
    18781 atccatcttc atttcattgt atttagtttc aaactcttta ctcttgttta attccatagc
    18841 tgatacattt gtcaatgatg ctccaattgc cattactgtt aatgccatta ctataccact
    18901 tttaaatttt tttactttca tatcttacct cctaaattaa atgttctcaa tgaaattata
    18961 taaagaaaat cctaagtttt acagtttcat tcttgtaact aaaattacta ttatgtaacc
    19021 aaactttttg cttcaactat tccttaaaag ttgctttttt gaggaatagt tgaagttaaa
    19081 taattagatt ttatctatat ttatagattt aaaatcaaat ttatccatat aaataaatac
    19141 ttatttttgc aaaataaaaa tttttaatta ctccaatcct tcttatttac ttaaaatcct
    19201 atgataagaa atttaaaagt ctttaccttc tttaacaata atttatttac ttttaacata
    19261 caaaatatag agagtatatc aaaatcattt tactgaatat tctaaaaata agtaccccct
    19321 attagtatat atatttacat attaaaaaaa agttttaaat aaagttatat tttttacaac
    19381 agttttgtaa ttaaaaacat attgaaggta aatttaaagg tactatatac tataaatatg
    19441 tcgacacaat aaatttaaaa aggagaatta aatatgaaaa aaagattaat aataatgata
    19501 ttgtctgttg tcttagtact atcaagtata cttacgatat ttgcatattc aaatattaaa
    19561 tataataata ataaattgat atattctaat atgatagata aaaaaactca aaatagtgta
    19621 aaggaaatcc taaaagaaaa taaaattaat gaaaaagaca tagatacatt tattaaagca
    19681 gtcaacaatt ataataaatt gcaagttaaa atacttcaaa ataatataaa tatatctaaa
    19741 tctggatatt cttcaatcaa tgcaaaacaa gttccatata acctagaaaa attgcaagat
    19801 aattgggtga aaaaattccc tgattatatg gatgtaaatt gtagaataac tgcttttaga
    19861 ctttttaaag attttataaa ttcaaataag aaatttactg gagactctat tgatttgaat
    19921 gtcgacttgg acactataat gaataataaa gatgctaaat ttagcatcaa agatgtagaa
    19981 aaatttatca acttcttttc tgcaatacca gctaaagata cagatgatac aatcaaaatt
    20041 tcagaacaaa taaaaaatga atggaaaaaa agaaaaatat cttttaaaaa taataaaaat
    20101 atatctatta taaatggatt tcttcgttat ccagaaacta aaaacgtatt tataggtcat
    20161 acaggcatat gtattaaaac taaaaatggc attctatttt tagaaaaata cggtgttaca
    20221 tcaccttatc aagttactaa atttaaaaat aaagaagatg taaaaaatta tatgtttaat
    20281 agattgaaga tgtcagaagg tgaaattgaa ttacctgacc ctataataat ggaaaacgat
    20341 aaacttatga aataataact ttaaacgcaa aataatattt ataattacta agtcaatata
    20401 atagagaagg tctatagatt tgtgtaaata caagcttatc tacaatctta tataagaata
    20461 tttatataaa taagatagat taattctaag tcctattatt ctattgaatt ttattattat
    20521 tttatttaga ttctattgtt attttactta gaacttatta ttattttgtt taagttctat
    20581 tactattttc aatcatataa atttacaaaa gactgtacat aaatttattt tatacaaact
    20641 tatctacagt cttttgtgtg aatatatcta aacaatatcg tatttattta tttcctctgc
    20701 acagtgagaa tcagaaccta aaattaatgg aatatcgtat ttttttacca actctaataa
    20761 gtatccatct atataaggct ctttgcagta ctcttttcta tttccagaaa cattataatc
    20821 aagttcataa cctttttctt taattaactt tattaactct tcaagaattg tatttccttt
    20881 ataatcgtat ggaaatacct gattaaactt tctaactaaa tttaaatgac ctattctttt
    20941 tggtttatgt atacctaaat ctgaatttac agcttttatc aatgtttcat aatacttatt
    21001 ataaacagct tcaatacttc ctaatttgtc gattaaattt tgaaactcct ctacactgta
    21061 atctacacaa taataatcat catcaatctt aattatatgt actgataaaa gagaatcctc
    21121 taattccttt ccatatttat ttaaattctc ctttatccct tcttcgtatc cttctataaa
    21181 atccacttcc gacccaacat ttatcttgat tttaccctca tacttttctt tcaacttctt
    21241 gacatcatta aaatactttg gtaaatcttc aatactcata caactatcat tttcaggagc
    21301 agggtctcta aatccatttg catacggaaa atgttctgta aatgtcattt ctgttattcc
    21361 aacatccatt gctctttgta catatttttc aaaatcatcc ttacttccat gaggacaata
    21421 aggtgaatgt atatgaccat ctttcataaa taattcactc cttttttaaa gaaaaaatct
    21481 aatataaatg cataaatctt ttaacttcaa aataatattt ttaatcatgc taatttttat
    21541 tatatctaat attagagtaa ttttaaactg ccttttaagt atcttatcat tagtactatt
    21601 ttcaacttaa cattaatatt attttttaac ttaacattaa tactatcttt aaatagtaat
    21661 actcaatata taattactta acataaaata actcaaattg cttgatgagg cttttgcagt
    21721 atttaaagaa tatataatta tttaacatta aataatccaa tcttgtaata aaatttactc
    21781 attaaagtat attacagaaa atacctcaaa ataaactttt tagttcatga tatactcttt
    21841 tttgcatgaa attagatata tttttatcat ttcaacaatg aaagggaggc ttatatccat
    21901 ctttagacaa ccccttagat aaaattttta ataattaaac atcacaaaat ataaaaatcg
    21961 cttatatcaa acgtataagc gattaattat atttacatat gttttttagc ctctaacaac
    22021 attttattag cttcttccat atactctata gccttttcaa tactctttgc tgtttcttct
    22081 tttccaatag ctctagcctt ttcaacccac tctctaaatc cttcttcatg agtttcattg
    22141 tgatttatcc aatgtactaa aagtattttt aaagtttttt catccttaga ctctgatgat
    22201 tcctcatgac tatgttcgtg gtcgtggtcg tgagcatggt catgtggatg ttcatgacat
    22261 atatctccat gagtatgttc gtggcagtgg tcatggtcat gatgtccatg atgatatctt
    22321 acaatctctt tatcaaaaat cattagttat tccccctgtt attttatatt aaactctttt
    22381 tttataaggt ttacagaatc ttttacaagt agtgctaatg gtttaccttc taatccaact
    22441 aactccacat tttctggcat aataggtaaa agtatcttaa gtgcctcact gtctgcaata
    22501 gcttcactta tattacaagt aacttctccc atcatagaat taggtattat tacagaaata
    22561 ggtgcaacta ttatatttgc ttttttagct gatactacta tagcattttc ccctgtagct
    22621 cctttattag catgagcttt catcatagaa ctagttgcta tagaattagt ccctagtgca
    22681 taaatttcta catatgtagg taactcttct ctcaaagaag aaactatctg ggctccaata
    22741 cctccaccca ttccatctat cactgctatt atcatatgaa attcccctat taattaattt
    22801 tcttgtatta ttatcttatg gtccatcaat cttatttctt taattatccc atctattatc
    22861 ttttgctctc ctaataaatc cgttaaataa atctttccat cacaagggtc tatattaacc
    22921 acattttcca taaccttttc taactcatta ttacttttac aaatgaaagc tgatgattca
    22981 cacatataaa tctcctccta atatgatttt tattaaaaat caaaaaaaga ttcccttagg
    23041 tatttcaata caccaaagaa accttcatga tttcagtttt tgtatattat tataccttaa
    23101 gtatatcact ttaatttatg taaagtcaat taaagttaac gctttttatt atactcttca
    23161 ttcttgtatt tttcatatag ttctttaact aattgcttct cataatcagt caaatcgccc
    23221 tccacaaact caacattaaa ttgttcagct aatcccttta ctatgttttt ctgtagaata
    23281 tctatgtcta tttttctgcc aatttcattt tctattccac ttgctttttt agctgtaaat
    23341 ttcatagctc tttctttcaa ttctggtgtc ttagttttta ttaatttaaa caatttttct
    23401 acatcaaaat ccagtattat tgaaccatgt tgtaataaaa caccatcttt tctgctttga
    23461 gcacttccaa ttaccttctt attattaata gtaacttcat atgatgcatg tgcattaaaa
    23521 catgcagctg ataaattttc cctacttatt ctctcgcctc tatttaaatt atctgtttct
    23581 ataccactta gattcaaccc tttaactaga ccttcactta tatatctata agataggttg
    23641 atgctcttat cgattaaagg attatcttct cctataatta tactataagt tagctcatta
    23701 tcatgtaata cagctcttcc acctgtaatt cttctagtat agtctatatt catacatcta
    23761 cacttatcta aatctatctc atcttccaat ttctgaaaat atcctatact caaacaagct
    23821 ggttcccatg tataaaatct aagagttggc ttattatgtc ccttcttata tgcagtaaat
    23881 atagcttcgt caattgccat attcattgct ccttcatatg atttattatg tataactctc
    23941 cactgattca tgattattac gcccccattt ttagtataaa tatatcctag aaatcctcta
    24001 tagatttatt tctcttattg ctaaatctat ctcactttga tttaaaggtc ttgaatagtt
    24061 gtatatagta cttcctggtc tttcattata gtatggtcta ttacaatcct tacaacctct
    24121 tatttcaaaa ggatagcctt tgtttatgtc ttttaaaata tcattgtcaa gctttatact
    24181 atttaagtat ccatttttaa acttaaaata ctcttttgga taacctttat ttatcatata
    24241 agacattaac tgtacccttc tataactttc tatgcttggt tgatttatct tttccatttt
    24301 agttcctcta actggagtaa atgcaaataa actaatcgtt acatcatttt cctttaaata
    24361 agtatataaa ttgtatatat cttcatgact ttcacccata ccaactatta tatgtgtact
    24421 tattttattg ggatatgatt ttgacatttc agttataaat tttaactttt catcatagtt
    24481 atttcctttt attttttcat atagttcttt atttgctgca tctattgcta ttcctatttt
    24541 atcaactcct actgaaaaaa acttctttat ctgttcatca ttttctaatt ttgcagatag
    24601 tgaaattggc atgtctatct taccacttat atagtttata aagtctaaaa cagagttatg
    24661 tgcttcttca cttgccattg attgaataca tattctcttt atattttttc ctttataagc
    24721 ttttaaagca tctaatattt cttcttttga aaactctggc caaattactc ttgataattt
    24781 atcttttcta gtactacttt ctattgattg agaacaaaaa ctgcatttat ttatgcattt
    24841 ttctccaatc attatatatg ctgtggtagg aggtatatcg ctttttttgt ttaatatccc
    24901 aagttctatt gctgtcccaa ctgatagtct aatcataaaa cgcaacactc cttacactca
    24961 tttattgtca tattcatttc tatagcctta ttctttgcag accttgatgg taatactatt
    25021 ctattgactc cacacattat agataattgg tctagctctt ttctatacac tcctcttggt
    25081 ctcatacaac ctagattaat ttcagtatct ggtaaattaa ttctagcttc acataaaata
    25141 tctgctaccc cttctaactc aggaggttct acattttcat actcagtccc ttttgttgga
    25201 ataaggacta taaatgtaag cttattagga ggattttttt gtaggtattc tataatttca
    25261 tattcaccct ttatttgtcc tccttttaaa ccaatacata tatgtggtgc tacttctgta
    25321 tgttcttgta ttgtattata gacttcaata taatcttctt tactcttttt catcttataa
    25381 acttctctta ttgtctcatc atcaaacact aaatcaaaag aaactatatc taaatactta
    25441 cacaactcta caatgctatc tttatccata agacctaaat gagcattcaa tctatatcct
    25501 tgctctttta agtttttaat ggtattaata tgagtattta tagggacatc tccctcataa
    25561 ctacaaccgc cactcaatag aaagctagtt atattccttg attgtacttt ttcctcatat
    25621 tcttctattg gcaccatatt gtttaagtag tgaccgttgc aatgggcaca tttcaaacta
    25681 cattgattgc ttgtagtact aagagctagt gtctggttag gataagcaaa ctctatttta
    25741 tttccaaaat tctttaattt aatatcaaat gctatttcca ttttttcaga tagattctta
    25801 ttcatagttt attccttctt aagtacattt tactcttcta gtaatttctt tgctgttggg
    25861 aactgctcta tattcgtatg tggtaagaaa catgcagaaa taaattcatc catataactt
    25921 ggatatacac taagttcaac ataagttatt tgattaccta tttcttcaag tttatttttt
    25981 gcatctttac ttataagagc taagtaagaa ccaacaagtg aactattccc tatataagta
    26041 aatttttctc tatcaatatc aggaagtaac cctataatta ttgagttttc tatgtctagg
    26101 ttgtttccta taccacctgc tatataaacc ctatctaata tactaaaatc catacctaaa
    26161 ctatctacaa gagtgtatgc gcctgaatat atagctcctt tagctctgat gaaattatct
    26221 atatcaactt cattgactac tatatcattt tctaaatcaa attcttcttt aaatgctaat
    26281 acatactctc ctatctcatg ctcattaaat ctaactctct tattatctaa atccctgtat
    26341 attttacctc ttctatctat taccccttta gtaatcattt gacagattaa atcaattata
    26401 ccagaaccac atataccaac tggtgcacat tcatcaataa tctttaatgt tggctctaaa
    26461 gtttctttat caataattac tttctctatt gctcctgctg atgctctcat tccacagctt
    26521 atccctccac cttcaaaagc aggtcctgct gaacatgcac agctcatcat ataatcttta
    26581 tttccaaata caatctctcc attagttcct aaatctataa ataaaacatt ttcttcactt
    26641 gaccatatcc ctgctgataa tacacctgct gttatatctc ctcctacata acttgcaaca
    26701 gatggagcta agtacacata tgcactgtca tttacaaaaa gaccaacatt ttcacccata
    26761 agttttggag attttaaaaa tggtggtatg taaggttctt gtcttaagaa gtctgtatac
    26821 acacccaaga ataaacttgt catagttgta ttcccagcag ccactaatgt aactacatct
    26881 tccttatcta ttccatttct ttcatatatt gtttttaata gtggatttat agtttcctca
    26941 actatagctt tatgaagtgt ctctaatcca tttttcttag ttgaatatat aattctattt
    27001 ataacatctg ctccatattt tatctgtgca tttccagaag atgctttatc tactacctct
    27061 tttgagtata ggtctactaa acaaacaact actgaagttg taccaatatc tattgcaact
    27121 ccgtataagg aattttcttt atttccttgt tctatattta tgattgtaag tttcttttgt
    27181 ttttgaacat atgttattgt aaccttaaaa tcactctttc taaatacagt tggcattttt
    27241 ctaagtatat ccaatctaaa atctatttca ttatatccta ggttatttct aacatatctt
    27301 tccaatctat ctacatcact tatattatca tctaaatttg gttcttccat ttctatgtat
    27361 ttctttttta tatttgtttt aaattgaagg ttatgttctt caattatttt tttagctctt
    27421 tcaaaaattt ccctatcctc ttttttatta ctaccttcta tcttcatacc atgcatagaa
    27481 gatgatactt tagaaggaac ttcaatttct atatctgata ttacctttgt acaacaagct
    27541 agtatataac cttgctccca ctcatcatct gttatatgtc ttgttttttc tgtatcaact
    27601 tttccattca ataattttac tttacacttc ccacaagaca cgtttccatt acaaggagca
    27661 tctatgaata tatctgcatt tcttgcaacc tctagtaata tatccccctc attacaataa
    27721 acctctttat tgtttggtgt aaaacttact tttatcatgt tatccctccc aatttgttct
    27781 atatatgata aaaggaaagt atagctaaat ttgcgtgcac tcaaatttta ctatactttc
    27841 cccaattata ataatatctt aatctttaat tattctaatc cagcctcgta ttctttatca
    27901 cttaataacg tatcaagttc agccacatca gctagtttta cttttaatat ccagttttca
    27961 tatgggtctt catttataca ttctggctca tcttctaatt tttcattaac ttccaatacc
    28021 tcaccattaa caggagatat taaatcagaa gctactttag aagactcaac tactccaaaa
    28081 tctactccct tagttacagt atcttctact tctggtgttt caacaaacaa tatttctcct
    28141 aattgatctt gagcatagtc tgttatacct atatatacaa catctccatc aattactttt
    28201 acccactcat gatctttaga gtattttaat tctggtaata atttcatttc gatagacccc
    28261 caatattata ttattgatta aattacttaa atcatattaa tattatatca tattatttta
    28321 aattttccat caattacatt acactttcca tagctaatgc tggatgacct ttttcttcta
    28381 agaaagctaa tactccttca gaatcgtcag ctatagtttc atcacaaacc atatcacaga
    28441 agttttctat tccagtcatt tctttaactg tagcatttaa tttatcagct acataatctt
    28501 ttaattcttt tggcatccaa actattcttt ctggtccacc ttctgcataa gcgaattttt
    28561 tagaagatat gaaatgtctt ccgtgtccca taaatcctgg agtttgaact cctccacctg
    28621 tcatagaagc aagttctccg aaagtcatac caactggagt aacacttgca aattctctgt
    28681 taactacaac aaatccattt gcttctggca ttataccaca gatacattcg aagcatccac
    28741 aagaagtcat tgggtcttct agtatagagt ataatgtaac agattcaact gcaccttgag
    28801 atatttggtt tacagtttca tttactgaat tccatacacc tgttctatca tctaagcact
    28861 cgcctttttc tattggttga caaggacctg ttgggtctaa ttctttagta gccttagcat
    28921 ctaaccagct aactgctcca caaagaccaa gtctttcagg agtaacaaca caaacgtgag
    28981 ctggtgcaaa tgattgacat aagttacaag aatagaaagt atcaacactt tcatcaacta
    29041 atgaagctaa tctttcatct ctagcattgt acttagctat tgcttctcct tttaattcag
    29101 aaactttttc agcatctgta attatagtta tttcacactt atcaactact gattcaaatt
    29161 catctaacat cttagcatat aaaacttctc ctatatgctc aagtctaaat cctttatcaa
    29221 atgcatcttt agagattctt acccaagcca tatctctttg tccaacgtgc attacacctt
    29281 ctatatagtt taagaagtag tggaaacgtc tttcaagaac tggctcgaaa tcttcttgca
    29341 tatttttacc agctatttta actattacag caagtggtaa tcttaataca ccatctgcat
    29401 caacttcatc tatatttggt cctattattt ctatcttatg gtcttcaact tctgttgctt
    29461 ctttcttaac aacaagctcc caagcttcag ttctgtttcc accaaactca gcaaacatat
    29521 cgctctttct aattctctca ccttcaaatg ctgctgcaaa tgaaactggg ataggtattt
    29581 cagtaacttt tatttttatt cctctagctt ctaatgaagt agctactatc ttatcgtaat
    29641 ctttttgagt taataggttc attggaactt caagaactgt ttggtcagtt ataactggga
    29701 atcctaaagc tattgctcca gcacctgcag atacaactaa ttcacttaat ggtccaaatg
    29761 cattaacaaa tgcaggaact ctattagctg tgtactctaa taatccgttt aaatcaccag
    29821 gagttaatcc accgaatatt aatgctgctc ttactgcaac agatacaacg tgtataacag
    29881 aagttacatc atatcctaga ggtataactc ttagctcaag acccattttt actccagctt
    29941 ctatagcttg gtctataact ttaccaacta agaaagttag taaaccttta gattggtaat
    30001 cttttataac ttttgctgct gattctgcat ctggacactc accaagaaca actgcaacac
    30061 caggtatatc tcctgtaact aatggtacac caagtgatct gattataggg tcagttatat
    30121 gacctgcaca tggctcacta tatggagcat ccatagttga atattttaat gcttcaatta
    30181 cttctgctgc taaagctgta gctaaaccag cattaaaagc atgttctagt aaatgagttc
    30241 tatttattaa agattttact acttctaaag caccttctaa gtcccctaaa gtgttcatct
    30301 tttgtcctgt tgcagcatat atacaaggta atgaatatgc tgtatcaggg aaagcaactt
    30361 tatgctcttt tccattcttt tctatagctt cagctaacat agcttgagcc gcacctaaag
    30421 cttgttctga ccctgtaaag attatattat atagattcat tctatttccc cctttaatat
    30481 ttacacctat tttttattaa ctatacccta aaaaccctag aaagcaaatc caccttcatt
    30541 taactctaag aaagagtctg catataaaga tgccccgttg attatgtcac aagattttac
    30601 agttttcatt aattctgggt cacatggatt cattatagct gaactaaatc cattagccat
    30661 tgccattgct aagaatgcac tatctaaaac aggtctaaca tgcttaggac atccattaga
    30721 tacgttagat aatcctcctg tagttaaaag tcccatctca gtcatcattt ttatagcttc
    30781 taaaacttct acttgttttt cttgcatacc ttttataact aagcataatg ggtcaaatag
    30841 tatatcagtt ggctccattc ctaacattaa gcctttttct aatatttctt ggcagtaagc
    30901 catacgctca tcattatctc ttgggatacc ttcttttgca cataaaccta taaccattgc
    30961 ttcgtattca gctgctatat ctattaaatc aaatcttgaa ccagcatcag cagagtttat
    31021 tattggtttt gcattagttc tatcataaac tttaagtcca gcttcgatag cttttttatt
    31081 agctgtatct aatgctatag gaacattgtt gaactcagat tgaagtaatt tgattcccca
    31141 tgtcattatt tcttcgccat ctctttcggc aggtcctata ttaaaatcta tatagtgtgc
    31201 tcctgcttct aattgctctt ttgctctttt taagattgga gctgggtctc tttctgctaa
    31261 tgcttttctt attgaaggtg atatacaatg tattctctca cctataatca taaatttttc
    31321 catttataat gtcccccttt aaatttaata ttaatagtta gttaatattt tattagtttg
    31381 tttggcatgc tttttcttgg tatcctttta agaacttagg taattccata gattcctctg
    31441 gtcctataac tacattccat cctggtaagt tatcttctat atcaccttta agtactgcaa
    31501 cttttcctgg aatgataagg tctttacaat tagttacttc ttctacctta ctttctttaa
    31561 tgaaagcaga gattgagttt ccaccaaatt taccagcagc ccaagatgta agaactgaat
    31621 atccacctgc atctggtatt actaaccata ctggaacttt tgatctttct atatcaccag
    31681 caactatgaa gtaagttaat gcaaagtcaa cagtaactaa tactggagaa ttttcatctg
    31741 ggttgttgat tggataaatc tttggttcaa ctctcattgg tctttgtggg tcagtgtata
    31801 tgttttgtct tagtgcaaat aatggtaatg ccttagcata actaatatca tctattacta
    31861 ttatagaacc gtattttata gtgaatattg atgataaagc aacttccatc atagggtttg
    31921 aattagataa tctatttgca aatactattg aaggatatcc aaatgttcta tcttgctctt
    31981 ttaaagctgt tcttctaact tgtatagcat tagtgtaagt atcttttatg ttttctcctg
    32041 ttacatctaa tactaattct ttatatccag cagcttgaat taattcaact gtttcatata
    32101 attcttctaa gctaccagct tttacaccta atggtaaact tgctccttta actacttcta
    32161 tcatatcttt gtagttctct ttagttgctc catataccat tggtctagca tcttttaata
    32221 cttcaacagc ttctttaact acttgtgcat catcacaagc taaaatataa gctacttcta
    32281 atccactgcc ttttatttta tctattaatt ttaaatacgc atctttatct ccacaatact
    32341 ctaaaacagc catttcaact ttcatttgtt caccaattct tacatagtca acttttttca
    32401 tgttagctat tttagcatct actgcttcat cactcataca agtacagaat gaaactgcat
    32461 atctatttct acttactaat gttttttcat gtctaaataa tactgtttct ccacctagtt
    32521 catactcaga tgcaccagca ccaactttta aagctttcat taaaggtgca gtagcctctg
    32581 ataattttgc tatagcgtca tcagacatat gtgggcattt acctacttct acagctcctg
    32641 aagcaacctt catagagaaa gccatacaag ttgggaatcc acaatcctta cagtttttct
    32701 ttggtgttaa tttaaatata tctaaagctt ttaatgccat tattttttcc ccctaacctt
    32761 aacaatttaa ttaagctaat gcgttaacca attcttttat agtttctatt gattttggat
    32821 gacgaagtat aactgcgttt gaaccaccta ctaaaacact tgctgcagtt gaaacttcca
    32881 ttgctatagt tctttcttct ggacaacccc aatctggctc atcttctatt ggagctatag
    32941 cttctttaac atgacctact tcaaaagcta ctggtgttat gataggcatt tgtaatgtct
    33001 tatcattttg accaaatgct gcaagtctaa ttctatccat agtagatgca acgtactcat
    33061 atccataacc aactgctgaa catccaacat tcataactat attttcacct ttaacgccta
    33121 gttgagttaa caatacgttt aattgtttag ctaggtttat atcaacagaa gattcagctc
    33181 ctactttatg tgcataagcc ataccagctg atgctcctac tcctttgtag ttatcttcta
    33241 ctgctgacat aaataagcag ttatgtccat ccaatgtttg agctaatttt tcaaataatt
    33301 taccatcttt ttcatgattt cctgaaccag ctacaactaa aggtaatttt attgcttcaa
    33361 ttactgcctt agctacatca gcacattcat caactgactt atctaatcca tttgggtcag
    33421 aaccatcaaa ttttaaacaa ataaaatctg cttgtgtatt agcttcaaca tatttagccc
    33481 actctactgg acaattagct acatctttgt ataattcctt atatgaatca gtccagcttt
    33541 caggataaac atctgatatt tgtatcccta tttttggaga attacctact tctccatcaa
    33601 aactataaaa aggtaataca ttttccccac ctaatttaat tgctttttcc cctattccta
    33661 cttcaacttc tgatattttt ccagaatatt tttgagtaga cattttaaat gccatatttt
    33721 tttccccctt aagcctattt taattctaat ttagcaaaaa tttctttcat agccacttta
    33781 gattttgaat cttcaggtaa attaactaaa ggaatacctg tagaatcata ttcatatatc
    33841 aattcatcca taggtacaac accgattagc tctaggttat gcttttcaat ttcttcttta
    33901 acaccatcat tcataacccc atttggaact ttatttacaa tcaaaagtat tcttccaaca
    33961 cttaacttta gttcctcagc taaatctctt attctagcaa cagcttgtat gctacgtctt
    34021 gagcaatcac taaccaataa aagtgtatca acatgtctag tgacttttct acttagatgt
    34081 tccataccag cttcgttgtc catgactaag tatttgtaat gaccagatat tttgtttact
    34141 tgttctctaa gtatcccatt tacaaaacag taacatcctt caccttctga cctacccatt
    34201 actaataagt catatccttc gccttcttcg attatagaat ttaatctaaa ttgaagatat
    34261 tgtgcctttg tcataccacc agggaatgca ttgcctaact tttctctttg atttacttct
    34321 tctcttattt ctcctattgt tgcttcaact tcgataccta atacttcatt tatgttagca
    34381 ttggcatcag catctacaac taatactggt ccctttttgt ccttaaccaa ataatcaatc
    34441 aaaagccctg tgagacttgt tttaccagtt ccaccttttc ctgcaacagc tatattgtat
    34501 cccattttaa gacttccccc ttaaatctag ccacagagcc ttatgtactc tgtctgtcta
    34561 ttataattta ggtacagaat gaacacattc tccatgtaca tcatgaagtg cttccattag
    34621 cccttcagat aaacttggat gtggatgtat tgcatcccct acttgttcta ctgttaatcc
    34681 tagatgaaca gcaagtgaca actctgtcaa taaatctgta gcatgaggtc ctactactgc
    34741 tgcacctatt atcttatcag tttctttgtc agctataact tttacaaatc cttggaaatg
    34801 tcctatagct tgtgcttttc caagacctct aaaatcaaat tgacctacat tgtattctac
    34861 accttcagct tcaagttgct tttcagtctt accaacacca gcaacttcag gttcagtata
    34921 aacacatctt ggaattgctc tataatctac taccttagtc ttacctaaag cattttcaac
    34981 tgctacgata ccttctttag aagcaacatg tgctaggaaa ggagtatcta ttatatcgcc
    35041 tattgcgtat ataccttcta cattagtttc aagatgttca ttaactacta cttttcctct
    35101 ttccatttca attcctatat cttctactcc agaattgtca aggttaggtc ttctaccaac
    35161 acatactaat gcatattgtg cttctataac ctttccatta gaaagagttg caacagcctt
    35221 accatcaact acttcacaag tttgtactcc aatacctgta ataaccttaa ttttatcttt
    35281 cttaaattgt ctaagtagtt gtttagctac atctttgtct tcatttaata gtatttggtc
    35341 aaccatctca actatagtta cttctgttcc caaggctcta aagaactgcc ctatctcaca
    35401 tcctataact ccaccaccta ctattaacat agactcaggt atctcttcaa gtccaagaac
    35461 ttcatcacta gttattacaa cttttccatc atatgggaac attcttggta caactggaac
    35521 agaaccattt gctagtatta tcttatctgc ttttatagtt tctactgttc catcatcttt
    35581 agttacttct atagtgtttt tatcaattaa ttttccaaaa ccattaacta agtttactcc
    35641 tcttttttca aataagaact ctataccact tattaattgg tttacaactt tattttttct
    35701 ttccattatg gcagtgaagt ttggcttaac tgtaccatct atttctatac caaaatcctt
    35761 tgcttctttt acagtattca atactcctga agaagcaaga agtgctttag ttggtataca
    35821 tcctgcattt aagcaagttc ctccaactct tcttttttca acaactgtta catctgcacc
    35881 aagcatagaa gcttttatag ctgctacata tcctcctggt ccaccaccta ctactactat
    35941 cttcatcttt aattccccca aacctaatat aatctacaat cttgcaatac tataaacctg
    36001 cggcatccag tatagcaggt atattctctt ctgccccaat tgccattata tgaacaccat
    36061 cacataaatc ttcttctttt aattgtttga taagttcccc tgccattttt attccttcac
    36121 ttacccagtt ttcttttcca gctgctctta atctttcgat ttgttcatct ggaacaaata
    36181 ttcctggtac atttgcagtc ataaatttag ccattcctgg tgattttaaa ggtactattc
    36241 ctgctaatac cttgcaatcc atatcccttg ttaattctct aaactttctc attgtattta
    36301 tgtcataaag tgcttgtgtt tggaaaaatt tagcccctgc ttttattttc tttttcattt
    36361 ttaataattg aacttctatt ggagaatatt ctggagttac tgatgctccc agataaaaat
    36421 ctggagaacc ttttaactta ttaccagcca tgtccgtacc tgccattaaa gtctcagcag
    36481 tttgaagtat ccccacagaa tctaaatcaa acactccctt agcttgtgga tggtctccta
    36541 cgctagtatg gtctcctgtt agtgccaaca gattgtttat cccaaataca cctgctgaca
    36601 acatttctcc ttgtatagct attctatttc tatctctccc tgttatttga ataactggct
    36661 ctaatccagc atcttttaat aatttacatg tagcaagaga agttgctctc ataactgccg
    36721 attgaaagtc tgttacattt gctgcatgaa ctcttccaac taacggcttt gcacattcta
    36781 ttaaatgtga aaggtcagtc ccttttggag gagccatttc agtagtaact gcaaattttc
    36841 cactttctaa tgtttctctt aataagctca tctctaatcc cccttttaac cttctaaaaa
    36901 aaacttttat gaatttgctg ctgcttcttt ctttttcttt gcacttaaac ttcttggatt
    36961 attttgctta gaatagtctt ttggtggtct tatttctgct aagttatcta attgtcctat
    37021 agcttctagt ctttcatata tctttatcca agcacaatca ttctctgagt ttacttcaca
    37081 cttaccattt ttagctccac cacaagcccc attcataaga cctttagcac acatagttac
    37141 tggacatatc ccacctgtcc aaccaagttc acagtctcca caagccttac aggcttcttc
    37201 atattctcca actctttgta cttcccctat aaacaaagta ttgttggctg gataaactgg
    37261 cttatctttt aaattcttaa ctattgtctg tgtaccatct ccacatgcta aagataaaac
    37321 tgcatcagct tccttagtct cttcctttag agcctttaaa tcctttttag actttaaaag
    37381 gttacaagca gggtcaagca ttacatatcc taagattttt ttgccttcac cttcaagagt
    37441 ttccttcatt tttaaaactt cttcttcccc accactttta caagttgctg cacattgatt
    37501 acaaccaact aaaaccagct tgtcaaaatc ttttaagtac cctagcactt cttctaatgg
    37561 tttattttca gaaattatca tatctacttc ccccctaaac cttccacata tatatatcta
    37621 tttattgttt tgtaatttac aagccttaac tacatgtttt gcaagtatag atgttgtaac
    37681 tgaaccaacc cccgctggaa ctggagttat cattgatact ttgtctaaaa ctgcatttgt
    37741 atcaacatct ccacataaat ttccttcttc atcaacattt ataccaacgt ctataactac
    37801 cgctccatct ttaacaaaac tttcatcaac catcttagct ctaccaatag ctgctattag
    37861 cacgtctgcc tctgctgcta cacctgatag atttttagtt tttgaatgac atattgtaac
    37921 agttgcatgt tcacttaata aaagcattga tactggcttt ccaactacca ttgatcttcc
    37981 aagaactgtt accttacttc cttttaaatc aacattatag tgttttaata tctcaactac
    38041 tgctgtaggt gtacatggtg gaaatccact tttatcccct tccattacct tagcagagtt
    38101 tattggacta aaacaatcta cgtctttttc cggtgcaata acatatttta taacttcttc
    38161 atttaagtgt tttggaagag gtctaaaaca taatatacca ttaacatttt tgtcatcatt
    38221 aactctcttt aatacatcaa tatattcctc ttgtgttata tcctcagcta actctaacac
    38281 ttctgttgtt atacctatgt tttgacatct ctttagtgct cctctttcat aagataaatc
    38341 atcacttctt gccccaactc taactattgt tagtttagga tttatacctt ctttaattag
    38401 taaatcgact tcttttatta attcttcact aatcttatca gctacaggtt ttccttttat
    38461 aatttgtcct ttagttgaca ttccttccat acattcacaa ctcccctaca agcaaactta
    38521 aattaattta ttctatatac cacatattaa taacatagta tctactttcg tcatttaaaa
    38581 attattttcc aagagctttt tcaactttgg cataaacttc atcacaaatt tttacaccat
    38641 cttcaactaa cttatctact tctgttttta ccttattaac atattcttta tcttgtatag
    38701 aatttatatt tataactaca tttaattgtc caccaagtat agcagctctt aaacactgaa
    38761 ctcctacacc aacatcactt atagcaagtc ttgaaccttt atcaactaaa tcttcatgta
    38821 acttaatagc ttcatagcaa actcttacta tgtttaatgg tacttcacaa gcaactttta
    38881 atgccttttc cattgtttct gcttttattc ttttttcttc ttctgtttct ttaggaagcc
    38941 cgtaagcttt tgataatggt aagaaacatt ctgcatcatc atctatcatt tttaataaat
    39001 ctttttctaa ctttcctgcc ttacttaata tctcttttac actttcttca tactcagcat
    39061 acttcttctt ccctattgta aggttacata ccatactacc taaagccata cctattgcac
    39121 ctactagtgc agcagctccc ccaccacctg gtactgcttc tttggaagat agtacttcta
    39181 caaaatcaac acaagtttta tctgctattt tcatgataat cctccttgaa aggatgtagg
    39241 aaaatatctc aaattgttcg agatatttta cgaactattt taagatatct cctactcttt
    39301 atttataaat taatttcctt agaataatcc agctattact ccattttcat caacatctat
    39361 tttttctgct gctggaactt ttggtaatcc tggcatcttc attatttctc cagtaagtgc
    39421 aactataaat ccagctcctg ctgaaattgt tgcttgtctt acagttattc taaatcctgt
    39481 tggtctacct aatttagttt ggtcatcagt taaagaatat tgagttttag ccatacatac
    39541 tggaacttta gtaaatccaa gtttttctaa gttagctatt tccttatcag cttcaggagt
    39601 ataatctaca ccatctgctc cataaatctt agtagctata gcatttatct tgtcttttat
    39661 agataaatca tcttcatagc agaatctaaa gttattttct tcttcatcca ataatcttaa
    39721 aacttcttta gctactgcaa ttccaccttc tccacctttt gcccatactt cagaaagagc
    39781 aacattaaca cctaattcct tacacttgtc ttcaacaagt ttaagttcag cttcagtatc
    39841 aagtgggaat ctattgattg caacaactgc tggtaatcca tatacttgag ttatgttttc
    39901 aacatgtttt aataagtttg gaagtccttt ttcaagagct tctaggtttt cgttatttaa
    39961 gtctgcttta gcaactccac cattgtattt taatgctctt acagtagcaa ctattataac
    40021 agcatctggt tttaagtttg ccattctaca ttttatatct aagaattttt ctgctccaag
    40081 gtcagcaccg aaaccagcct cagttattac ataatctgca aagtgcatag ccattcttgt
    40141 agctataaca gagttacatc catgagctat atttgcgaat ggtccaccgt gtacaaatga
    40201 tggtgttcct tcaagagttt gaactaggtt tggttttaaa gcatctttta ataatgcagc
    40261 catagcacca ttagctttta attgtctagc tgttacaggt tcaccttcgt agctgtatcc
    40321 aactattatg tttcctaatc tttcttttaa atcagatata tcacttgcca aacagaacgc
    40381 tgccattatt tcagaagcaa cagttatatc gaatccatct tgtctaactg ctccatcacc
    40441 ttttttaccc ataccatcaa cgatatttct aagttgtcta tcgttcatgt ctacacatct
    40501 tctccaagtt attttcttag ggtctattct aagtgcattt ccttggtgaa tatggttatc
    40561 aagcatagca gctaaaagat tgttagcagc tcctatagcg tgaaaatctc ctgtgaagtg
    40621 taagtttata tcttccatag gaacaacttg tgcatatcct ccaccagctg ctccaccttt
    40681 aacaccaaat actggtccta gagatggttc tcttaaagca actaatacat ttttgtctag
    40741 tttagcaaat gcatcagcaa cacctatagt agtagtagtt tttccttcac ctgctggagt
    40801 tgggtttata gctgtagtta gtattaactt agctttttta ccagtctctc tttttagtag
    40861 attgtagtca acttttgctt tgtatttacc ataaagttct acatcatctt cacctagtcc
    40921 taattttttt gcaacctctc taatatcttg aggcttagct tcttgagcta tttcaatgtc
    40981 agatttaaat cccataactg aatctcctcc cacaacctaa atagatttaa aatataattt
    41041 ttgtaaaaat tgtattaata tgtaaaaatt atattttata agataattat acatgtaaaa
    41101 ttacttaaaa actagctact aagctattaa aatattcaaa cttaatagct agttatttat
    41161 ctaattactt acttattacc tatctattgc ctatgtctaa cctttaacca acttaaaatc
    41221 ccaaatcaaa atttctatct attttactta tccttaagtg acattaattt atcttttatt
    41281 gctttaatct gttctttcgt tgtttcacta gaatcatatg gagattgatt agctctatca
    41341 gaatcaataa catcttggtt ataataaata aatcctaaag attctccatc ttctaagttt
    41401 tggattataa attcttcatc ttccttattt ctaattttat ttcctactac aaatacttta
    41461 tttacaccta tatcatgtcc aagtttctta acttttctat aagtctgtag acttctctct
    41521 cctggttcta caactactat aaaagcatct acaccttggg ctgttcctct tcctaagtgt
    41581 tcaattcccg cttccatatc cataaccact acatctttat tttgtagtat taaatgtgag
    41641 cagagtctct tcaaaagaac atgctctgga catacacatc cagtaccacc agaatctacg
    41701 gttcccaatg taagtaatct tactccattg tattctttac agaaattttc agggatatcg
    41761 tctactttag gattcatctt aaacattttt ccaaatgaac ctacagaagc agctgttcta
    41821 tctgaaacta attttttcat ttctgatata ggtactattg attcatatac ttcttttgga
    41881 aaacctagtg ctaaagctaa attagcatca gggtcggcat caacagcaac aactctgtat
    41941 ccgtcttcag caaacatcct agagagcatt gaagaaaaag tcgttttacc tactccacct
    42001 ttacctgtta ttgctatctt cataatccct accacctttt attactattt gctttttagt
    42061 agttaatttt acagttaaat attttttata ctctatattt ttatacacta aaaataaact
    42121 acagctagtc cttacaggaa ccaattaaat ttaccctact agcttttcaa agcagcatgt
    42181 atagttttat tattctttaa tattgtttat attttattta ttcagtatat tcattatatt
    42241 ttgatgttct ttactttaat atttgacttt attcaacttt attcaaccag aaacttctta
    42301 taaaaacgtt tattctataa cttcactatt ttttaagctt cagccttttc tgccattttt
    42361 tcttcaacta atgcttcaaa gtgaacacgt tttttctcta tatcttctat tattgtagct
    42421 gctaactctt ttggatttgt atttacagta aatgtagctc caactttatc ttttaattca
    42481 ctagttaata tatccactgc tcttgaagaa ccagctattg gaggcattat tcctaaataa
    42541 gtgtctatac cagaagctac aacatagcat cctatagcaa ctgctttttc tgacatccac
    42601 tctggagcta tacctacaac tggaaggtca cacatatcca tatctaagta attagctgct
    42661 gctccaacta aatctagtat acggcttata tcaacacaag aacccatatg tagtactggt
    42721 gggattccta ctaatttaca gacagttgca agacctttac ctgcatattt ttcagccgca
    42781 tcagattcca ttaaaccaaa cttagctgct gctgaagctc cacaacctgt agtaactact
    42841 attatgtcgt ttttgattaa ttctttcatt attgttacgt gagcctcatt tgaaactcct
    42901 ttagcattgt tacatccaac tacaccagct gctcctctta atactccagc ttttaaacag
    42961 tctgttaatg gcttaactgt tcctgctggg tctatatgag agtttacaac tctgtctaat
    43021 tgatttacta ctgcttctac actataccca actgttgcgc ctgattttaa ttcaggtata
    43081 agtacttttg atttatctct atttttaaag tttaaaatag cttctttaac tattgcttta
    43141 gcatcatcaa gtgcttgttc ttctctaaat tcaatataag ttgaacctgt tatcttagct
    43201 tttggagaag ttgttacaaa tttagtatgg taacaatctg caactctagc taatgcaggg
    43261 aatatacatt gaacgtcaac tattacagct tcaactgctc cagttattat tgcaagttct
    43321 tgttgatgga agtctcctgc tatttttaca ccatgtctca ttgtaatctc attacctgta
    43381 caacacatac ctgctaagtt tattccatca gcaccaactt ctttagctaa agctactaag
    43441 tctggctctt ctgatgctaa aactatcatt tctgataatg ctggctcatg tccatgtaat
    43501 attatgttaa ctttattttc ttctaatact gctaaattcg cctctgttct tcttggcact
    43561 ggagttccaa ataagatatc gcttagacga gtacctatca tagaaccacc ccaaccatca
    43621 gccatagaag ttctaagact catgtgtatt aaactatcta tatcaccagt acatcctata
    43681 tgagtagagt gcattattgt tgcaatttct ctatctatag ctcttggctc tatagcgtat
    43741 tctttccata ttttttgtct tggttctggt gcatttttta taaatcttaa tgtcccaaaa
    43801 ggttttccaa attccattaa tgcaatttct gccacttcat gtgctacatc atagatatct
    43861 ctaccttctg tctctacatc ccattcttta gctaaagtaa ttaacttagc ttcgtctctt
    43921 attttatagt ttccatttgg atcagctaat gctaatgtat gtgctatatc tctagcatgg
    43981 tctgaatggg cagctgtccc accagcaacc attcttgcaa agtttctacc tactatagta
    44041 tgctcatctg ctccacataa cccccttgga gtcttagggc ttattctaca tggtcccatt
    44101 ccacatattc tacagcaaac accttgaaga ccaaaaccac attgtgcctt aaagccttct
    44161 tttctatcat acattgtttc tacgccttct tctctagctt tagctatcat cttctggctg
    44221 tttaaatcaa ttgttaacat tttttcatcc atattcctat cccctttttt tgatttttaa
    44281 aatcccccag gtgactgact tcatgtcata aaataataaa ataaatgctt tctaagttga
    44341 ttatatacta attttcagtg ctttgcttta gatttaaata tttttttaac aaaattagat
    44401 aatacataaa aattttattt tctacactta atttaagttg attttatcgc ttgtttttgg
    44461 ctatttgtta atatctaaac ctactttttt gatacttcag tttaattaaa ttatgttttg
    44521 atttttttaa atcaaatttg aaatttttct agtcattttt atattattgc agattgtttg
    44581 tgtatttatt atctttcact actgtttgga cttattacag atttttactc cctaaactta
    44641 attagtaaaa atttcttaga atagcatttt ttggactaat ttttttgaat ttttttattt
    44701 ttcctacttt aatattaatt atagcttcaa attgaacatt tgtatatatt catttgaagc
    44761 tataattatt ttttatataa aactttttta atacagcatt aatttagaca ttttgactat
    44821 tttttctact ttaattcatt tatttcaagc gatttatcct atttcatatt tttagctaca
    44881 atagccccat atgcaataga atataattta gattcatgtg aatcagctct tgacactaaa
    44941 actataggag cttttgcacc cataattata cctgctgatt tagagtctgc catatatgta
    45001 aaggctttcc ctattccatt accaacctct attgttggaa ccaatatgat atctacatct
    45061 ccagatactt cacttttaaa cccttttatc tcactagctt cttttgaaac agctaaatca
    45121 aaagccagag gaccttctac aattacattt tcaccaaatt ctccttcttt acaagctttt
    45181 gctaacatat ctgcatctac agttgcttgc atcttaggat ttactttctc tttagctgcc
    45241 aaacatgcaa cttttacagt ttccattcct aaagcttttg cagcttttat agaatttttt
    45301 aatatctttg ccttttgttc ataatcagga gctatattca tacctccatc tgtagttata
    45361 agtaatttat ggtatttttc taactcatat accataacat gacttaataa actatcagtt
    45421 ctaagaccat agtctttatt taacacttct tttaatatga cagatgtatc taataatcct
    45481 ttcattacaa agtcagcttc tttacttgat actaatttaa ctgctatttc tgcacactct
    45541 ttgatatcat ccttatccac tattttgata ccacttaaat caaatcctat ttcttttgat
    45601 atttctctta ttttgccttc atttccaacc aatataggag taattatatt tctttctaca
    45661 gcatccttta ttgccattaa aacttcttta tcatgagctg ctgctacaga gagtacaatt
    45721 ttctctcctc ccttaagttg ttctaaaata tcatctaatt tttttatcaa aagtaacccc
    45781 tcccttatat atatttaact aaataatacc atatttgcta taccttttct caatttattt
    45841 tttatgttat aaagaattta tataactaaa agacagttta atattttatt ctgggatttc
    45901 atcaatagct cttaaaagct ttgcaggaac accacctaca atagtatttt ctgcaacatt
    45961 ttttgttaca actgctccag cagcgataat tgcattatct ccaatagtaa ctcctggaac
    46021 tacagttaca ttagcaccaa tccatacatt ttttcctatt gtgattggag aaggataagt
    46081 tgtaccacgt ttctctggtg caataccatg gttaagtgta gccaatacca cattatgccc
    46141 aatttgcgta ttatctccaa tctcaatccc cccctggtct tgaaaatggc aactgctatt
    46201 tataaaaaca ttttttccta ttgtgatgtt ttttccacaa tctgtataaa atggtggaaa
    46261 cataaaaaat gattcatcta ccttttttcc aattaactca gaaaataaac tacggacttc
    46321 ttctggttca tgataagaag aatttaactt acttgtgatt ttcattgcct cattactcaa
    46381 cttaaccata aattcatgta tttctgattt actagaaaca ggttttcttt gattgatatg
    46441 tgttaaaaat tcattgatat tcattttata catcctttca atatgtgctt taatttattt
    46501 gtacattcta aataatattt taataaaaat taatttaatt tatttttatt aaaatatcat
    46561 tgcttctttt agtgtaatat acaattatat ctatatcaaa tatctatatt aaatacttaa
    46621 ctatacttaa aaagcatata aattgatata attatataat aaataagtta atattgagga
    46681 gggataatta tggaaataag agtattaaga tattttttag caattgcaag agaagaaagt
    46741 atatctggtg cggcaacctt tttacatata acacaaccaa cactttctag acaaattatg
    46801 gaacttgaag aagagttggg agttaaatta ttggttcgag gaaatagaaa aatcacctta
    46861 acaaatgaag gtaggctttt acataaaaga gcagaggaaa ttatatcatt agttgataag
    46921 gttgaattag aatttgacaa tcccaatgag attattagtg gtgatatata tataggaagt
    46981 ggtgaaactg aagctatgcg acttatagct agaactgccc atcattttca tcaaaaatac
    47041 cccaatgtaa gatatcacct ttttagtggg aatgctgatg atgtgactga aaaattagac
    47101 aagggactgc ttgattttgg tattttaatt gaacctgcaa atatacagaa gtatgattat
    47161 gcacaaattc ctgctactga tgtatggggt ttactaatgc gtaaagatag tgcccttgca
    47221 tcacaaagca caataaatcc aaaagattta tgcaatatac ctcttattat ttcaagacag
    47281 acacttgttg ataaagcaat ttctaaatgg cttcaaggca gtaatgaaaa actaaacatt
    47341 attgcaacat acaatttagt ttataacgct tctcttttgg tagaagaagg tctgggctac
    47401 gctctgtgtt tagatagact cgtcaatact acagaaaaca gtaatctttg ttttagacct
    47461 ctatctcctc ctttagaagc taaattaaat attatatgga aaaaacatca aatattttca
    47521 aaggcagcag aaaaattttt acttcaaata caaaaagatt tttcttctat catgttggat
    47581 acatctaagt tggatacacc taaagaaaaa taaatcataa taaaaagtga gagtgtctca
    47641 aaatgaactt tgcactgtat aaggcactct tttttataca aagtaaaata tatgttcatc
    47701 atttcagcac taaaaaagag gcttatctct attttgagat agccccactt aaccaataaa
    47761 attaaataca acttaacaat atccttactt atttattcca agttctctta gacaagcaat
    47821 cgtaatttca tcttgtggat ttaattcata agctctttct atatagtaag ttgcatcatc
    47881 aatatcacca ttatttaaat aagccattcc taaattgcaa agtatttctg ggtcttcctt
    47941 tatcttagcc gcttgttcaa aatactctat tgctttatct aaattattct tataagcctc
    48001 acaaagcccc aattccacta tagtatccac ctgattaggc tttattatca atatcttctc
    48061 aagatacatc ttagcctgct ctatttcgcc cataccctta tatccaagtg ctatcataaa
    48121 cagcaagttc caccaatcca tatgttcttc ttctaatgga agtaacttct ctaatccttc
    48181 cttaaactta ccttggaata caagtgtata tccttcttca tattgaactt taaagtccat
    48241 cttgcccaga ttctcttgta cctcagctac taaatcagca tctaacccta gccttaacgc
    48301 ttcttcccaa gtcagcttag tctttaaata ttgaccttga ttataataat ggtagcctaa
    48361 gtgataataa cctaatgcaa aattctcatc aacatcaatt accttttcaa gcttagccat
    48421 ggcttcaagt aagaatgcat tcattgcctt atcatccata tctttttgat actgtttagc
    48481 tatctcttgg caaacaatcg catagttata cattgcatct aaatcatctg gatacattgt
    48541 tataaatgct tttatatata ttaaagaatc tgtatgttca ccaatctcaa agtattttct
    48601 cgacatatat cccatatacg atttcaaatc caaatcaata tcttttgata aagcatttaa
    48661 aaacttctca tactctgcat tgtttttaaa cttactatct attccaatta tatatatcat
    48721 tgcatctgct atagacattg aatttaactt atcttgagca gtcttttctt ttatcccttt
    48781 tactaatacc tcatttttta taggtacatc taatccacct tttggcactt catagctttt
    48841 taatttaaac tctccaccat gttttatagt tataaaagct aattcttctg ctttttttag
    48901 caaatatttt tctatcttaa aatccatttt atcctcctaa atacttaaat ctctacttta
    48961 tgagttttag atttctcaaa tattttttta tcatcatact caaataagac tacattttct
    49021 acttctctta tttctgtatt tatatcattt tttaaatcca caacattaaa tctaaatggc
    49081 tcaaaatgaa catattttat tatatgttta gctggtttat caacaaaact aggtaaatat
    49141 gttgataagt tatcattatc ttgtaaaaat acatggcatc tattcttaaa atcatccaca
    49201 tctagcttat taaaaaactg tggtatattt gatgttttac ccagtgatat atagtcatat
    49261 tttaatatat cgttgaatac atcattatct atgttgattt tttcattata gaaatccatc
    49321 aatattttat ataactgatt ctttccttgt gccaaatcaa agtagccatt ttcatcaaaa
    49381 tacttggcaa aaacctcaaa gaatttaaaa gggctttttt tataaaatct gcctataata
    49441 tatctcatag ataacacaaa gtttttagaa ttgtagtatc tctccagtat atcttctata
    49501 tcctttagct tcaaagtttc ttcatagctt atataattat tgtataaaaa ctcatatgga
    49561 gcataatcct tatatttaaa accatgctca tctgcaactt ttctcatacc tgtcccttta
    49621 atcatcttta aaaagcctaa ttgcagatgc tctataccta gattaaatac atcattaaaa
    49681 gaattttcaa agctcttata atcttcataa ggcagtcctg caattaagtc taagtgttga
    49741 tgtatatttc tataagatgc tacagtttgt acaacatgag acaacttttt aaaatcatcc
    49801 cttctaccta ctgcatcaag tgttttttca ttcgttgact gaacccctat ttcaaattga
    49861 aaaagacctt ctttacaatc agccaaaaac tcaagcatct tatcatctat caaatacgct
    49921 gtaacttcaa aatgataagt tgtatatcca ttatcatttt tcataagaaa atccatgatt
    49981 tccatagcca cttttctatt tgcattgaat gtcctatcta taaactttat ttgtgatact
    50041 cttgcatcta ttaaagcttt taaatcactc tttatcctgt ctaaactaaa ataccttaga
    50101 cctggaatag tagatgataa acagtattgg cagttaaaag ggcaacctct tgatgattca
    50161 taatacacta ttctattttc atattctttt ggattcaagt tttcataagg actaggaatc
    50221 tcatccaaat cttgaagtaa ttccataggc ttattcacta ttatctcatt gccttgtcta
    50281 tatacaagtc catttacatc atttatttcc atctttcctt gcaagtgaag tactaaatct
    50341 ctaaaaatta attctccctc tccataaagt atataatcca caaaatcata ctttttcatt
    50401 gcctcataac tatcataact cacttccggt ccgcccaaag ctattttagt attaggtcta
    50461 atttttttta gattatcaca aagtttaact atatctccca cattccagat atatgttgag
    50521 aataatatta tatcatattc atttttatat atatccttta aaatatagtc caaatcgttg
    50581 tttatcgtgt attctttcat attaacttct atcaaatctc ttacaaattc ttttagatat
    50641 cttatagcca aatttgtatg aataaacttg gaatttaatg ttgttaataa aattttcaaa
    50701 tatttctcac ctctttttaa gattatactg tctttttgta ccccttatag gttaaaatag
    50761 tatatgtaaa gtctaaataa tatctatata attaatttat taatttcaag taatgtgagg
    50821 aaaggaagtt ttttatggaa ttaattgaaa aagtatctat caactcttta tcaaaaagag
    50881 atttactact tattataaag tctcttgaat acactaatga aaatactcaa attagtgatt
    50941 tcattgacct taggaataat atagtaaagg aattatgttt tttaactgac actaaggaaa
    51001 aagatttttt agattatcta gaaaaaaata gcacactcta ataacctaaa cctttttaaa
    51061 ctttaatata taaatacctg atttagaatt tatttttatg cttaatatat tatcattaaa
    51121 ggttttcgac ataactgtta tttgattaaa tatagggtct actatagtat taccttcttc
    51181 aagtcttata agacttcttg ggtctatgct tttattatat gccttaactc caattttata
    51241 ttttctcaat ttaacaacat attcggacat agaaaaaata aaatctatat tatcttcatt
    51301 taatttacta tcttcaccca aaatggataa tatagatttt tttatgctat taattccttc
    51361 attttctaca gttctatctt ccatatatac atcatataga acatttaaaa catttaataa
    51421 aatactttct tcatcataat cttcagattt caaatcaatg tacttatcaa ttaattgtat
    51481 tgctttaatc cttgccatct gaaactttac aacatctgat ttgtctaatt ctatagaaaa
    51541 tcctattatc ttgtctttaa tactctgtag taattcgaca tactctattt tactattatt
    51601 tataagattg tgcataatgg aattatacac cacagaacct aataaataat caaataaaag
    51661 ttcttctttt ttaaaataaa taacatactt ttttattagt ttaataacct catcttcact
    51721 tttttgaata ttagtatttg ataaaattag tggtaataaa atatttaaaa aattgatatt
    51781 tcctattttt tctccataaa atctatagta aataagttca tctctcagtc tattttcgtc
    51841 tatatacaca catctttgcg ttttatcatc tattaaggat tttgtattta ttatagttaa
    51901 atctttaaga gccctacttg cactactaaa agaagatgtg tagacttttt ttagtaattc
    51961 gtcattcata aatatatcct ttctgaaaaa ttgaatgtaa ataaattgtt attaaaaaaa
    52021 aagagacagc ccgtttaaga agctgtcata tataggggga tagtagtgta caaaaatcat
    52081 tgtaatctac tatctatata ttattatacg atactacttt tttatatgta aagcatcagt
    52141 tttcgacatc cctatatttt acagttatac aaattgcgta ctaagttcaa ttttattctt
    52201 tttatttcaa cattttatca tgctacattc tttcaggagc gtgcattccc aacaatttca
    52261 gagaattttc taaagtttgt tttgttgcta aaactaatgc aagtcttgct tttcttattt
    52321 ccaaattttc tactaaaatt ggattgtcat gataaaattt attaaacgct tgagctaaat
    52381 ctagcataaa tctagtcact atatgtggct catttttctt tagagcaagt aaaatattct
    52441 tattgaatga ttctataact ctaagaactt ctgcactatc ttcatcagct aatagactat
    52501 aatctatatc agaagtcact tctacttctg cttttcttaa aactgcacag catctagcat
    52561 gtgtatactg aacatatggt ccagtctcac catcaaaact aagcgttctt tcccaagaga
    52621 aggtatagtc tttaattcta ctattagata actcttggaa tactactgcc ccaacaccta
    52681 cttgcttaga tatttcatcc acatttttag catttgggtt tttagctagt ataatttcct
    52741 tagttttatc tatagcttga tttaaagcat cttctaaaaa tactactctt ccttttctag
    52801 tcgacatagt accttcttca agtgcaacca taccaaatcc aacatgaatt aaatcttttg
    52861 cccaatcata tcccataagc tcaattacct taaaccattg ttggaaatgt aagttttgtt
    52921 gagaaccaac tacatatata cacttgtcaa aatcataagt ttcttttcta tatattgcag
    52981 cagctaaatc tcttgtcata tataacgttg aaccatcatt cttagtaata agtgctggtg
    53041 gcattttata ctcttctaaa tcaacaattc ttgctccttt agactctttt aaaagatttt
    53101 tctcttctaa tagttcgata actctgttca ttttatcaga ataaaaactc tctcctgcta
    53161 aagaatcaaa ttctatatct aaaagtttat aaactctgtt aaactctttt aaactctcat
    53221 ttctaaacca ttgccataat tcttgtgctt cttcgtcacc attttctaat ttattaaacc
    53281 atgctcttgc ttcatcttcc atttctgggt gttgttcagc ttcatcatgg aatcttacgt
    53341 ataattttag taattctgga attggattag actctactac ttctttttct ccccactttt
    53401 taaaggccac tattaactta ccaaactgag ttccatagtc acctaaatga tttattctta
    53461 tagtcttgta tccttgcgaa tcatatatct tatataaagc attacctata actgtagttc
    53521 ttatgtgccc tatatggaaa ggttttgcta tatttggaga agaatattca actattacag
    53581 ttttatcttt tccaaaatca ctatgtccgt aattttcttt ttcatctaaa acttttttaa
    53641 ttacagtttc tgctaattga gatttattta caaagaaatt tacatatccg cctaattgta
    53701 ttacttttgt tatctctcca cttggttcta tactttccgc caattcactt gctatcatgt
    53761 ttggagcttt tctaaacact ttggctaatt taaagcatgg aaaagcatag tcccccatat
    53821 ccttatttgg tggaacttct ataagtgcct ctatctcttc tttcgataaa tcttctattt
    53881 tttctttaag gcaatttgat attgccacct taaaatcttg cattctgttg ctcctctcta
    53941 cattgttcct ggtttatatt gtgcttatct ctttatgtta aatcaaattt cgtgtttttt
    54001 caagtatttc attacagtgt aaaacacttt agtaattatg ttttctgtat atattaaaaa
    54061 tactataatt tcagttttta atcacactat tattgatttt ttataagact tttttctatt
    54121 ttattgtttc ttgtactatc cagttgactt tatatacttt ttttaatctt ttatctgttt
    54181 tcatacatca atgtcagctt tatatacatt tttttaatct tttatctatt ttcatacatc
    54241 aatgtcagct ttatatactt tttttacttt tttatctatt tttatacatc aatattagct
    54301 ttatatactt tttttactct tttatctatt ttctataaat ctttttcact cttaactttt
    54361 attccttctt cttctaatag ccttgctgtt atacctttcc ctggtatctt tttacctgaa
    54421 aaactaccat catatattag attacatcca caagaggggc taccctcttt tagtattgct
    54481 tcgctacata catataaatt tgctattttt agagtttcat tagcccctct tacaaagttt
    54541 tctgttacat ccttattatc tttagtaatt acttttccat caactatctc agcaggtggt
    54601 cttggtgtag atagaccacc taactgctct gggcatacaa gtgtaaattc tttgcctttt
    54661 aaatattcct tgactttttc attatcatta ttatcgccac tatatttaca atttattcct
    54721 attaaacatg cagataccaa tatcataaaa atgtgctcct atacaaatta tatatattct
    54781 catacaaatt actaatgtat tcttatacaa attattttaa tttaacaatt gttactcctg
    54841 ctccaccttc tccatattga ccacctcttt gtgattttac atgtctattt cttcttaaaa
    54901 tgtcttgtag ccctgctttt aatactcctg tacctattcc atgtattact gttacagact
    54961 ctaaacctgc cacatatgca tcatcaagat acttttctac ttccattata gcttcttcta
    55021 ggtttaaccc tctaaggtca acttcatttt ttacactacc agattttgac cttataatgt
    55081 ttctcgttga tttagttaca tttgttgaaa catctttgcg tgttttttgt aaagatttaa
    55141 aaggtagagt catcttcatt ataccaattt gcactactgc ttcttttctc tttttatcta
    55201 ctgaaactac actaccattt tgatttaaag ttattacctt aacttcttca cctggcttta
    55261 agtcttttat ctccttattt gatacctttg gaactatcat actttttact gttggctgaa
    55321 gacttcccat agagctagtc aattcttttc taagttcttc tatcttacga ttcttttctt
    55381 ttgaagctct ttcttgttca agacttctaa gttcttttat tataatatct acttcttctt
    55441 tagcttgtct tataattgaa aatgcttctg atttagcttt ttcaatcatc ttatctcttt
    55501 gactgaccaa tttttcaagt ttttcgtcat actctacttt cagtttttca atctcttctt
    55561 ttaatctttc agcttcttct ctatcttcta ctgctttgat tctattcttt tcaacattct
    55621 gtaacacatc ttctaaagct atgttttctg tatttatata ttctttagca cgtgaaatca
    55681 cataatcact tagcccaagt tttctagaaa tctcaaacgc atttgatttt ccgggaacac
    55741 ctataagtaa cttatatgtt gggcttaaag tttctatatc aaattcaact gctgcgtttt
    55801 ctacacctgg tttagtaaga gcataatttt taagctcact atagtgagtg gtagctatac
    55861 atttagctcc tacagaattt atatcttcta atactgctat tgcaagggca gctccttcaa
    55921 cagggtctgt tcctgctcct aactcgtcaa atataactaa agagtctgct gttacgtttt
    55981 gtaatataga tactatattc gtcatatgag atgaaaatgt tgatagactc tgttcaatac
    56041 tctgctcatc tcctatatct gcaaatacat tatcatatac acacatacta cttccataat
    56101 cagcaggtat atgaagtcca ctttgtgtca taagtgcaaa tagacctaca gtttttattg
    56161 taacagtctt accacctgtg tttggacctg ttatcaccaa tgtatggaag tctcttccta
    56221 aataaatggt atttgctact accttctttt tatccagcag tggatgtctt ccatttttta
    56281 tgtttaaata tttatcctca tttaaagttg gttctattcc tctcatctgt atagaaagtt
    56341 ttccctttga aaatgcaaag tccaatcttc caagtatctc ttgattagag attaaatctt
    56401 cgctcacttc tccaaccata gcagaaagct ctgataaaat tctttctatt tcttcttgct
    56461 cacctagttt taactgtctc aattcattgt tcatctctac tatagtcatt ggctctataa
    56521 aaagtgtcgc accagaagat gactggtcat gcactatacc agctacttgc gacctatatt
    56581 cagattttac aggtactaca aatctatcac ctcttagaga aattattgca tcttgtaagt
    56641 acttttgata agtagttgaa cttattattg aatttaattt tgacctaatg gattgatttt
    56701 tttgggctat tcttcttctg atatctctaa gtgtacttga agcattgtca gatatttcta
    56761 cttcactaat tatagcattg tatatctggt cttctatgtc cttgtataca tatagagaat
    56821 ttgatagaga ttgtattatt ggataattaa aatcttcttc atcactacta gataagctat
    56881 ttcttaatct tctagccact cttaaggtat ctgctatcat aatcagactt cctgggtcaa
    56941 gagaagcacc tatataagct ctctttacct tatcttctat atcatgaata ccttccaacc
    57001 ctactgaacc tctctttata ataattgatt gagcttcact agtttcttct agcatagatt
    57061 tcacttctac aaaatcagta tttggtacta aattttctat atattttaga cctaaagaag
    57121 atgaggcttt cttctttaac aaatctatta ttttattgta ttctagaact cttaacgatt
    57181 tctcattcat tttctatatt caccatcctc gatattttaa cttttttatt taattttaaa
    57241 aatgtatgtt ttcaagcatt tccaataaaa actgcaagtt ttatttcttt ttcatttcta
    57301 aaattattat attttttctc ttttagatat attttacaca tattttgtat tatactatgt
    57361 atgtagctat ctatatatta tacataaaca tgctttattt gtaatataat ctgttaaaaa
    57421 atcttcttta atatttttaa aggagtttat tttagcttat aaaaaaaaat agctacttat
    57481 atagataaat taaggaggaa catgagtcat gggaaacgta ttagaaggat taaaaccaga
    57541 aagtgttttt aaaaactttg agaaaatatc tcaaattcct agaggttctg gaaatgaaaa
    57601 aggcataagt gattttttac ttagctttgg taaaaattta ggtcttgaaa ctattcagga
    57661 tgaaagctta aacataataa taagaaagcc tgctacaaaa ggatatgaaa attgtccagg
    57721 tgtagttctt caaggacata tggatatggt ttgcgaaaaa gaaaagaatg ttgaacatga
    57781 ttttcttaaa gaccctataa aattaagaat tgatggtgac atgatatatg ctactggaac
    57841 tactctagga gctgacaatg gtatagctgt tgctatgggt atggctatat tagaagataa
    57901 tactttagag catcctgcac tagaagtttt agttactgtt aatgaagaag atggtatgaa
    57961 tggtgcagat gcactagacc ctagcttaat taaaggtcaa tatatcctaa atatggactc
    58021 cgaggaggaa ggatacttat tagttagctg tgctggtggt aaaacttgtg ttgttagttt
    58081 acctgttgaa tacaaggaag ttaaaggtga caaacaagga ttattagttg aggttactgg
    58141 actattaggt ggacactctg gtatggaaat tgttttacaa agagcaaatg ctaacaaagc
    58201 aatagctaga gtattaagtg tattgaatgt tgattatgaa ttagcttctg ttgatggtgg
    58261 tactaagcac aatgctatac ctcgtgaagc taaatgtgta atagctgtta ataaagctga
    58321 tgttgaatct gctaaaaaac aaataaatga cattttaact gcatttaaac atgagtttac
    58381 tacttctgac cctggcatga cttactcagt agctgaaact tctgtagaca aagttcttac
    58441 taaagattgt aaagaaaaag ttgttcaaat gtcttgctta actcctcatg gagttcaatc
    58501 agtaagtctt gatatagaag gattagttga aagttctact aacttcgcta taatcgaaac
    58561 taaagaatct actattgaat ttttaacttc tgttagaagt tctgttatgt ctattagaga
    58621 tgaaatcgct gatagaataa gacttttggc tcaagcttta ggtgctaatt acgaccttat
    58681 agctcaatac ccagcttggg aatttaaaaa aggctcaaaa ttagaaaaaa tatgcagtga
    58741 aacttatgag aaattaactg gtaaagttcc tactgttatg gctctacatg ctggtcttga
    58801 gtgtggatta ttacttgata aacttcctca tgctgaagct atctctatag gaccagatat
    58861 gtttgatgtt catactccaa atgaacatgt tagtatccct tctgtagcta atgtttggga
    58921 ttatgttatt gaaatattaa aatctatgaa ccaatattaa atttaagttt tgattctaag
    58981 tagattttaa ttttaagtaa tctatataaa attaactctg taaattaata ctacggttag
    59041 tataatattt actttcaata ttaacttata gaaataaagc ctaatgatag ataataacat
    59101 gtatcattag gctttattgt aatttaaata ttattaagct ttattctgtt ttaaaattaa
    59161 ttcttatact attttaaatc tatttcttcc ttgtctctta gaatcataaa gagcattatc
    59221 tgctatttga tacagttcat catactcttg accaggcttt gctataacta cccccatact
    59281 aatagataaa ctttctccat ttggcaactt aatgagatga atatgattgt atacatcatt
    59341 acatttatta ataagttctt ccttatttat tatatcattg atataaacac taaattcatc
    59401 tccacccaaa cgacctacta tatcattttt tgcaaaactt tcatcaagtg cctttgcaac
    59461 atcaataagt actttatctc ctaacaagtg accataagta tcattaatcg atttaaaata
    59521 atcaatatct ataatcaata aagcaccatt tttttcagtt gataaattca acaaattttg
    59581 tgaagttaat tttctaatat atgctgcatt ataaatattg gttaaactat ccctttgagc
    59641 cttatctaac aatctattct tttcctcttt ttcagaatca atattacata ttttcccgat
    59701 tacatacatt ggtatttttc tatcattata aattattttt gaagtaactc taatccaatg
    59761 aaaagtatca tcaagcataa tagaatacat ttcagttgtt ccattttctt gtgattttat
    59821 tacatcaaaa aactttttat tatattcttt ccttatttta tctctttcat tttctatatt
    59881 gccattttca ctttccttat catttttatc caaaccataa taagtctcaa tacccttttc
    59941 tggcatagaa attatcaatt tatcttgctt ataatcatac tcaaaaaagt attcacttgt
    60001 catttcatac aactgagtat gttttttgag ttctaaagat atcttctcgt tcatacttgt
    60061 acgagtatgt aaaccaaatg ccataaatcc aataatacaa attaataaac tggctacaat
    60121 aaaaatagtc tcaattggat tctgttgcat aatataaagc aacgagaaat cttgtctata
    60181 tgtagtattt tggtagacaa ttgattgcat tttttctgat gaaatactta taatagcttt
    60241 attaaatata ttcaataatt cttgtttatc ttttttaatt ataccaaaac aaatactctt
    60301 tgctttatag gtttgaggaa ctagacgcac atttttatac ttaggttgat tcatatagta
    60361 ctgcatagaa taaccttcgc cataagtgta atctgcatag cctttattaa cagcttctat
    60421 acactcttct aaattatcat accaaactat attctcttca aactgaccat aataattaat
    60481 acctttggct agagctacac gttttccatc taaactattc tcatttaatt tattattaat
    60541 catcatagta tattgagtag aaagaaaagg ccgagacata gctatattat gttcacgaga
    60601 gtattcataa tcataaatca ttcctgctac aatatcaatt tcacgctttt tagtcatgtt
    60661 ttctaaatct tcttgagatt ttacaggcac aagttcaaat tctaagcctg ttttatcaca
    60721 tatatgattt aacaaatcaa ttgatatacc tcttaattca cctgtatctt tatctatatt
    60781 ttgaaatggt ggtttgttta aaagtactcc tacttttaat ttttctgtct ctttaatgta
    60841 attagtttct tcatcagata aaaacatttg attattctct ggtgtaaagt atttttcata
    60901 taaagtagtt gaaaaatatg ggtctttctg ttcaatatta ttaattgctg agttaagctt
    60961 ttgagttaaa tttgtactac ctttaggagt aatgaaataa aatggttttg atgaaaattt
    61021 tgctacagta cgtacacctt ctattgggtt catactcaca ttaagaagta catctgcttt
    61081 accactcttt agtgcttcta gttgctcatc atttgtttta caatatacca attcaggtga
    61141 cataagattc attttacaat actcatctaa ttctttaagt ctagtatcag aattttctat
    61201 tacagcaata cggatttttt tcacatcttg tgaactcatt atgttatcaa tatctgtatt
    61261 ttcatataat gcttgtagta ctgtatttgc tactccataa ttattccctg cataattata
    61321 tattttttgc attggttcat tgtataacat acctcccatt atatcaattt caccattttc
    61381 taacatcttc attaattttg taatagattc atttatctct ccaggaactt gaacaaattc
    61441 ataattccat ccagtatact gtgcaatttc tagtaaatat tcatatgtat acccaaaata
    61501 gttaccttgc tcatctattt cagttaaacc tttttgaata ggataagcaa cacgaatggt
    61561 acgattatca ttacctatag cgttgatacc aaaagaaaat atgcaagaag tgaatataga
    61621 tgtaattaca ataattaata aaagtaattt ttttaaattc actacacaat cctccatata
    61681 gttaagattt acagtataaa ttactgcata aacttgtaga catgtaaaaa tagattagta
    61741 tataaaagga tatataaatc tacttagaaa tttaaatatc cttaatatat acaatatatt
    61801 taaattataa ctcatttata tgtctattac aacaaattta ccctgctaaa tacctactct
    61861 atatcccata attttacaag ttgtagtgaa gtttaagttc tatctcacct caaatttagc
    61921 agtgtttcta tttacagttc ttttatattt cacatctgga taacccaata taaatgaagt
    61981 gataactgct tcgttctcgc tcattcctaa cagttctttt atctttggct ctacatttga
    62041 tgccataaca aaaaatccat tataacaaat tcctaatcct tgagaatagg ccataagttc
    62101 catattagat gcagccaatc ctccatctac ataagcactt ccacctagag acatatcacc
    62161 tacaactacc ataagtagtg gggcatcata aaataaagaa tcatttccgt tctctttgta
    62221 tcttttgtac attttcttaa atgtattttt atagatagaa cgtacagggt cattgtcatc
    62281 agtatctaat gccaaattat aaagaccttg tattgccagt tctttcactt cttttagctt
    62341 ttcttttact aatatgtatc ttataggctg tctattacca cctgttggtg tgtatctacc
    62401 agcttccact atgtttttta ttttttcttc ttctacctct atatctttat attgtcttat
    62461 acttcttcta aatttaataa aattcaataa cttttcgggt tctaattcaa aactttcacg
    62521 attgtattct attacttcat ttttatcaaa tccttgcatt tctattgcat ctgttgggca
    62581 aattgccata cagtgaccac agttaataca gagaatattt ttaacctttg ctttatcatc
    62641 cttaactttt attgcattta caagacagtc tgattcacac atcccacagc ctacacattt
    62701 ttctaaattt atgtctatca ttccaaatta ttcctccttt taaaaaattt actttagtat
    62761 aaaacaaata gttgtctaag tcaattttta tttttttaac aatatactag ccttaactac
    62821 actttaatgg agaaaaatat acataaattg gaacttaaat tagaacttat tcaaagtaaa
    62881 agataaaaga agtagatgtc taaaagtgaa ctttttagtt aattagatat tctttattgt
    62941 atgaaatcaa gtggatattt atcatttcaa caataaaaaa ggcttacctc tattttggat
    63001 atgtccctgt caagtagaca gactaaaaaa aggctatctt tatgcactga gatagcccct
    63061 tttcccaact actattgttt atcttaatat tagtcaataa atttaatttg ctataacctg
    63121 taagttacat tttaatttga tgtaacttta aattacattt ttaagtaata tctttaaatt
    63181 atattcttaa aatatatcat taaactacat tttaattaat ctaaaaacta tatcttaatt
    63241 aatctaagaa acttacatta taatctttta gtttcccatt atcatataca atctttgcac
    63301 taaagatatt tccagtctta gcccaattta agaacagcct gtcaccttcc cacatattta
    63361 aatcgaatat tttatcatta tcaacccaaa ttaaatttcc ttctttacaa tcatttaaat
    63421 ctttttcaga taattcacct tcaaactcat ctgagaaata caaaaacata taccaatctt
    63481 cttcatcttt aaattttgga aaagttatca accctttata tgacaatgat ttaagagtaa
    63541 gaccagtctc ttcttttact tctctaatta cacattcttc tggagtctct ccttgctcaa
    63601 actttcctcc aactcctaca tacttacctt catgtatatc atctttcttt ttatttctgt
    63661 acaacatcaa agtcttgtca tctttttcta tataacaaat agttgtaagt ttcatgtatc
    63721 tcgccttgct ttctctttta tattctcaac taattatttt cagcactttc aagcacatca
    63781 cttatattct tcattgcatt aagagaaagc tctgcaaatt catcaaatgg aatccctata
    63841 tcttctatac ttctcattgc atctctattt acatttgaag caaatctcgt ttctttcatt
    63901 cttttaataa cagacttagt ctttacactg gtaagttttt tatctggata aactaaagct
    63961 atagcagtta taaacccagt tatagggtct gctgcatata ttgctttttc cattaggcta
    64021 gttcttgtaa ctcccattcc atcatgatga ccaagtattg ctctatacat ttcttcgtta
    64081 ccgaagtttt cttttttaag cagttctact gttgttgtag catgtccttc acatatttct
    64141 cctggctttc ttccaactat atctgaatcc aaatcatgta aaagacctgc cactgcccac
    64201 tcttcttctt tttctggctc tagtcttttg gctaattctc tcataacagc ttcaacagca
    64261 taacaatgtt ttctcattct atcagtttct aaatacttaa ataaaatttc taaagcttct
    64321 tctctcattt tcaccaatcc ccctgttttt tcacatatat gatattttta tatattaata
    64381 cacataaatt caagctttta tatatattca tgtatatttt tcatgttata tctattctac
    64441 acctttatag tagtgtcctg caactgttcc aatttcatct aatttcttat acaagtctgt
    64501 agcctttttt ccaagtttat aattattact cagtacctca atgtgagctt caataacctt
    64561 tttaaccatc tcactatctt caactgtaaa atctatccta aatacatcta ttccaatttc
    64621 ctctaactca tatagattgt ccaacataca agtaaccttc gaattgtaaa ttgtacttct
    64681 acagaatata tcttgtgtta tcctataact tgcatccgta aagtctctta aagcataact
    64741 actttcctta catttagcaa ctctcttgtc ctttttacaa tctctaacaa ctactcccat
    64801 aggacagtat tctgtaacca tcataggagc atatccatat attactgctt caatttctac
    64861 atctgtatat tttaaagttt gtttaatttc atttaagttt agttcttgtg acaaacaaac
    64921 tgtacttgct ccctcttctt tgaagtgatt tatactttca ctattgaata catttaagta
    64981 gcaatctata tttaagtctt ttttcttaaa gtattccata gagccccagt taccaatttg
    65041 aaccttatta attcctttta tattatccaa tatctcaaat tgcttgtact ctttatttct
    65101 aacaatcctt ggtgctgaat agattaattt tttgtcagtg actgctgtat tagagtggtt
    65161 cttattcaaa gtatctattt tacttgtatt tgacaaagta tctatgttat ttgtatttga
    65221 acccattagt tctttaggag tacctaaaga cgaagaagta tctaaatcca tagaaatact
    65281 tgaatctata gaaatatttg aatctataga gatacttgag accatttgta aagcttttga
    65341 taatgtattt atatcttcat aatagattaa atctacatta taatttaata ctgcttctaa
    65401 ttgctccaag ttcttaactt taactctaat cttaggagct gtatcaagtt ttttctgttt
    65461 atttactcta tttggctggt attttaatct attcttctta aattttctat cttttatctt
    65521 tattctttct tcatctaaaa gctcaataca atcccttctc atttgattta acacacttat
    65581 aggcatactt acaccttcat ccaggtcaat ttctatctct tttaacttat atggtgtatt
    65641 tccaagcttt tgaatttgtg tttctatttt ttctttactt aaagccacct ttatagcttt
    65701 ttcaactatt ttgtctcctt ctaccaccga tttatttcca caaaaatcac ttataaaaag
    65761 ctctggcttt ttacctagtt taatactcac ttttgcacgt atattagttt ttatgaactc
    65821 tttatcttgc tgaaatgtag cttgtactct atccattaat tcgctgtcag aagtcttata
    65881 tataagctga tttctctttg cttctccaac aaaatctaat tctatcaaat cccctttatg
    65941 tgctattgta gttatctctc catcctttat tattcttcca atagtacctc cacctaagtt
    66001 aattccatca cctttcttaa gcgtattttc tagcattact ctaagtcttt tgttctttct
    66061 attataatct aaaacttttc caatatatag cccttgatta ttaggtctat tagagttcat
    66121 tatatcctta ccaacttcac ctaatatata tccttttgta aactttctat taaatatggt
    66181 atacaaatta tttattattt cctcagaaat acttattttt ttcttatcta caaattcatt
    66241 aatcgcttct ctatatcctg aaaccacagt agctacatac tctggctttt tcattctacc
    66301 ttcaattttt aaagataata cacctgcttc aattatttta tccaaatctt ctatagtact
    66361 taaatctcta ggactcaaca aataatctcc attacttttt actacttctc ctgtatttat
    66421 atctatcaac tcatactttt gtctacatgg ctgtgcacac ctacctctat ttccagacct
    66481 attgcctatc atactactca taaggcattg acccgagtaa catacacata aagctccatg
    66541 tacaaaaact tctatatcta cagttgtatt ttcacaaatc cattttatct catcaacatt
    66601 taattctctt gctaaaacaa ctctatcaaa ccctacactc tgaaggtatt ttacatcttc
    66661 taaggaatgt gctaccattt gagtgcttgc atgtagttca aagtcaggta atagtttttt
    66721 tataagtctt gccattccta tatcctgtac tattaaagca tcaatatcta tatcgtataa
    66781 aaattttaca tactctacaa aatcttctat ttcatactgt tttatcaatg tatttacagt
    66841 aacaaagact tgcactcccc ttatatgaga gtatttaaca gcctcaatca gctcatttct
    66901 atcaaagtta tttgcagatg ctctagcact aaagtcttta ccacctaaat acacagcatt
    66961 tgctccgttt tgaactgctg cttttaatga atcaaaagag cctactggtg caagtaattc
    67021 tatttttttc atatttttct cctctattta tacttgttag gttaatataa ttatatctat
    67081 aacttaaata tttgtattaa atttatatat ttcttactat attttaaatt cttcaatcaa
    67141 tttatatatt agttatttat atttggttca tttgagttaa catatacatt atttactata
    67201 tttagtatat ttctattaac ttatatattg attactgtat tttaaattct tcaattaatt
    67261 tatatactgc ttactaaatt taaaacattt taattaattt gtacactgtt tactatactt
    67321 gaaatacttc tattaatcta tatattgcct actatactta agacatttta attaatttat
    67381 acactgttta ctatacttga aatacttcta ttaatctata tattgcctac tatacttaag
    67441 acattttaat taatttatac actgcttact atacttaaaa tacttctatt aacttataca
    67501 ttgcttacta tattttaaat tctttaatta atctatgcaa tatttgctat atataaagta
    67561 tatcaaataa cagcttcatt tttttgtaaa tttacagaaa gttaattttc attaaatgaa
    67621 tcatctttat tgataaacat aattccaaag accactgcca aaataaaaaa acatattagt
    67681 attgattttt ccacgaaaat ttttgtaaaa aaagttccta aaatagctcc agatataaag
    67741 aatataataa cagcataata ctgtaaactc ttttttatca taaaaatatt cttagtatgt
    67801 atataatgaa ataaagtttc tgtagcactt cttaaatttc cagtacacat tgtcgttgca
    67861 aaactattcc catttacttt tctaaaactc tctacttgca ttgaacaaat aaaagaaata
    67921 gcaacattta caaacatatt aaatcttcct ctaggaataa atgaaacaat aagtattgta
    67981 atcatttcaa ttataatgat aacctgacgc caatgaatct ttgtcttatt atttgtaaaa
    68041 tactttctta tcttctcggc tataaataca cctaacataa atgccaaaat aggaatcaaa
    68101 taataaaatg attcctttac attaccttct gctatattaa gcccaaacaa aactatattt
    68161 ccagtttgtg cattagcaaa gactttacct cttaccacat aagtataaat atccaaaaat
    68221 cctcctgtta ttgccaacaa agaacataaa aagaatgatt cagacatctg actcttgctt
    68281 gtcatatata aacctctcgc tttctaatga tagatacaaa atcaaaatca ttttagattc
    68341 tatttttcat tgatataaaa aaattattta tatttaaata ttgtctatat ttatacatca
    68401 tttatattta tacattaaaa gaagctgtct caaaaaacaa gagacagcaa atcttttagt
    68461 ttattccaca ttttttgcat cattatttaa ccctgtacat tttaactgta aatcataagc
    68521 tttgttttga aactcagaag ctaagttttc agctatagta gctctttcat ttgcttcttc
    68581 aagttgagta cttaactcct caatcttgtt tttataagca tctaactctg ctctagaacc
    68641 ttctgtcgta ttactaagtt cgaatatttc ttgcttttta ttttctataa tctcaattaa
    68701 ctctttcatc ttagtttcag cttcacgatt ttctgcttct ttttctgcta tcgtaagctt
    68761 taaagacttg atttctaatt gaagctcttc attagatgct ccaaccttct tactcaattc
    68821 ttcattagct ttaatcaact tctcattctc atctgaacat tcaaataaaa ggtctgatat
    68881 atttaatgca gttaatatcg cagcaactga taagctcaat ttcgggtttt gacgtgttat
    68941 tttatccatt tctttgtcta caaaatcagc aatactaatc ataaacttct ctgatttgtc
    69001 tccaaccatt ggatattcag cgccatggat tttaaccatt actttgttca tcctaacctc
    69061 ccccgacatt agttgttaat ttgatcttaa gttagcattt aatttttcgc ttaattcact
    69121 taatatctta tcatgcacct tagctacatc ttcatctgtt agagttttat ctttacttct
    69181 ataagttatt gaatatgcaa ttgacttgta tccagcttct atttgagaac ctttgtaaac
    69241 atcaaataac ttgtagcttt ctactaatcc ttgaccattt tcctttatta tatcttctat
    69301 ttgttttaca aatacatcat ctttaacaat aagagctata tctcttgatg tagatggata
    69361 ttttggtaat ggcacataat tctttgttct atcagaatta tcaaatacaa agtcaatatc
    69421 tatttcagcg acataaactc tttgacctag attgtagttt tctataacat ctggatgcaa
    69481 ttcacctaat gtacctacat atttattatt atacactatt ttagcacatc taccagggtg
    69541 gaaggtagta ttattatctt gaggttcaat ttcataacct ttaaatccga catttacaag
    69601 tatagtttct atagttcctt ttagtgcaaa gaagtcaaca tctttaccat acatacctac
    69661 acacattcta ttttcttcct taggtaattc tgaatcttgt gggatgaata tatgtccaca
    69721 ctcaaatgca gatacttctt ctattttatg agatacatta gttgataaaa catctaacat
    69781 atttggtatt aaagtagttc tcattacaga agtttcttct cctaatgggt taagtaattt
    69841 aacaaaattt ctctttgcat taccttctgg tactcttatc ttatctactc ccttagggct
    69901 tacaaatgaa tatgttaata tttcatttaa tcctacagca gttgaattat cttttaaagc
    69961 atccatgaat ttttgttttg aagttttaat tcctgctgtc gtatttcctt ctaattgtac
    70021 agaaggtata ttctcaaatc cataaattct agctatttct tcccatacat cagcttcttg
    70081 ttccatatct gttctaaagc ttggtacatc tatttctaat ttatcattag ctaccaaatt
    70141 acatttaaac tctaatgatt ctaaaattcc tacaaactgc tccattggta catctacacc
    70201 taatagatgg ttaattcttt gaggatttac taccaatttt ttaggttctg gtttatttgg
    70261 atatacatct acaacacctt ttaaaacttt tcctgctcct aacatttcaa caagctgtgc
    70321 agctctattt gctgctatct ctgcaagatt agggtctaag tctttttcat ttcttgaaga
    70381 tgcttctgac ctaataccaa cttttttagc tgtcattctt atgttttctg gtttgaaatt
    70441 ggcactttca aaaagtacag tcttcgtatt agaagttatt tctgagttag caccacccat
    70501 tacaccagct aaaccaagtg atttttctcc atttgttata actagcatat ctttgtctaa
    70561 tgttctctca acatcatcta atgttacaag tttctctcca tctttagcat ttcttactac
    70621 tattcttcca gtctctactt gatttatatc aaaagcatga agtggttgac caagctctaa
    70681 cattacgaag tttgttatat cgactatgtt acttataggt cttactcctg cttctgtaag
    70741 tcttctttgc atccaatatg gagaaggttc tatttttaca tctgtaacca ttctagcaac
    70801 atatcttcta cataaatctg gattatctat ctcaactttg aaatctatct cttcgtcact
    70861 ttcttttact tcgatttcag gatattttac ttttgttcct atagttgcag ctgcttctct
    70921 agctataccc atcatgcatt tacaatcagg tctgtttgaa gttaattcaa aatctattaa
    70981 agcatctttt aatcctaaaa catcttttat atcttttcct aattcataag aatcttcgtg
    71041 gtctaaaata tatataccac ctcttttata ctcctcaatg taatgttcat ctatacctag
    71101 ttcagctgct gaacacatca taccatctga taattcacct ctgaaatcag tctgtttgat
    71161 ttcaactcct ccaggtaact tagaaccatt tacagctact ggaatataat ctccttctga
    71221 tatatttgta gctcctgtaa ctatttgaac aactttatct ccaatatcta ctttggttac
    71281 aaccaactta tcagcatttg gatgttgttt tatttctaaa atctttccaa ccaatatatt
    71341 ttctatttct tcaccataat aatctattgt ttcaacttta gttcctgtca ttgtcatttt
    71401 atcagcgaac tcttttacat ccatgtctat atcaacatag tctctaagcc attttaaaga
    71461 tactaacatc tacataccct cctaattaaa attgatttaa gaatctcata tcattttcga
    71521 ataataatct aatatcatct atttcgtatt taagcattgc aagtctttca accccaactc
    71581 caaatgcaaa tccactgtaa acttctgggt ctattccaca atttctaagc acatttggat
    71641 gaaccatacc tgaacctaat atttctatcc aaccttcata tttacacatt gggcaacctt
    71701 taccaccaca tttgaaacaa gtaacatcaa cctctgcact tggttctgta aatgggaagt
    71761 tgtgaggtct aaacttagtt ttgatatcag aaccaaacaa tttttcaacg aagatatcca
    71821 tagttccttt aaattctgcc atagtaacat cttttccaac aacaagccct tctatctgat
    71881 ggaacattgg tgagtgtgta gcatctggcg agtctgacct aaaacatcta cctggtgcaa
    71941 ttacttttat tggtaactct tgacttctca tagttcttac ttgaactgga gatgtttgag
    72001 ttctaagtaa taccccatca ttgatataga atgtatcgct catatctctt gatggatggt
    72061 ctttaggagc gtttaatgcg tcaaagttgt tttcaacagt ctcaacttct ggcccttctg
    72121 ctatagagaa tcccattccg ataaatatat ctgttacttc atctataatt tgagttattg
    72181 gatgcttctt cccaaccttt aaaacttttc ctggttgagt aacatctatc acttcctctt
    72241 ttaattttct ttctttttca atagcattta tttcttcttt tttagaattt atgctaagtt
    72301 caatgttttc tcttacctca ttggcaacct taccaactac tggtctttct tcagcagata
    72361 atttacccat ttctttaagt atggcagtta tctcaccttt ttttcctaag tacttaactc
    72421 ttaaactttc tacactttct atgctttgtg cttcttttat ttcagccaaa gctgcttcac
    72481 gtaaagcaag taatttttct tgcacacata tcaccctttc gtttttttgt ataaaaaaag
    72541 cccctcaatc cctgtctagg gacgaaaggc tatagtttcg cggtaccacc ctagtagttt
    72601 aacaatttaa aaatcatcaa accacctcta acaaacttaa cgcgtttttg acgtcaaagc
    72661 ctactgtaaa atttcagctc tgttactcca gagggaactt ctcatgacct cttagaaaac
    72721 actcccagcc taggtgttta tctctttact aagtttaatc aaaatacttt cctctttcat
    72781 tgcatttaca atattatatt gtttatttta gtattatatc atttccattc aaattatgtg
    72841 actattttta atatatatcc aataca
//
LOCUS       DAMJVG010000010        71684 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.010, whole genome shotgun sequence.
ACCESSION   DAMJVG010000010 DAMJVG010000000
VERSION     DAMJVG010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 71684)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 71684)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..71684
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.010"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            256..633
                     /locus_tag="PC512_000749"
     CDS             256..633
                     /locus_tag="PC512_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2440519.1"
                     /translation="MMIRKIPQAELKVMKFIWKVDVTVTSKDVIEAMEQKYGWKQTTT
                     LTLLSRLVKRGFLDAQKIDRYTHYTIRVKHKDYLSFETKDFLSNIHDDSLRSLISALH
                     DDENIGKDKLDFLESYFDNLKDE"
     gene            626..1774
                     /locus_tag="PC512_000750"
     CDS             626..1774
                     /locus_tag="PC512_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease"
                     /protein_id="HDF2440520.1"
                     /translation="MNNYMLYVFENLIKTTIVCSLGICLLLFLKRYLFKKFSKRFNYY
                     IWLIIVFRMLLFLFNYTIVYEVKEPKENALGNNITQIDISTDNNLMLYVAYLWLFVTI
                     VIAVYTFIKYTRFKNLVVDVSYDIEDNDINCIYKNLLKELNIKKKIELRGSDELISPA
                     GMGLFKSYIFLPDYPYSKDELTWILKHELMHFKNKDILIKFLVLSVRIIYWFNPLVYV
                     MSNKVNLDCELCCDESVLVECSLKDKKEYALALIKSIKFSKNYNSKILTTEFDKTNLE
                     KRLESIVKKKGKSGILIAVLVFMTSITSFVEVDAQVRIDEGNNGMNNNINEFLLNKTT
                     DKIINIYYKDAPNEIRKFYEDKCELEGKIPRDYDIIEMDMKDYNQLIK"
     gene            1791..2393
                     /locus_tag="PC512_000751"
     CDS             1791..2393
                     /locus_tag="PC512_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-binding protein"
                     /protein_id="HDF2440521.1"
                     /translation="MLTKLRKIVAIMCCLLLTFTSVAFADTSKEKGGSKETVPEKNLD
                     SFTLSGYIYTYENAPQEIRDEHKQNCEEINIDPKPDDEIFVPESANLMNEDNSKGVYA
                     SYTVSYNIGAKTITIMSNEYLTISTTKVIRKGNSGKEVKAAQIMLTLLGYNVGIDSSF
                     GSKTYNAVVSFQKKYGLSADGIIGPATWDKLGRLTDPTLS"
     gene            complement(2486..3508)
                     /locus_tag="PC512_000752"
     CDS             complement(2486..3508)
                     /locus_tag="PC512_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HDF2440522.1"
                     /translation="MDYNDLLKSARENFNGTCKVCKICNGLACAGDVPGMGGKGSGSS
                     FIENRKSLEKIKINMRVIHNVSKPDTSIELFGRKMSSPIFAAPVSGTILNMGGKVSEK
                     EYIEPVVRGCSNSGIYAMVGDTNVDTFLLDNLDVLKDNRGNGIVFIKPWNNSKIIDKI
                     RLSEEAGAFAVGVDLDACGLINNQFQENPFSPKTIDEIRELVESTRLPFIIKGIMTVD
                     DALMAVESGASAIIVSNHGGRVLDYTPGTCEVLPDIAKSVKGKITILVDGGVRTGVDV
                     VKMLGLGADAVLMGRPFVTASFGGGLDGVEFFIEKVRNELCETMILTGCQNVKDIDGR
                     VIWNLL"
     gene            complement(3837..4019)
                     /locus_tag="PC512_000753"
     CDS             complement(3837..4019)
                     /locus_tag="PC512_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440523.1"
                     /translation="MYKDKSDECIHLMTAYIDSISGYYSFIDTQLEDFMMKYGENIVD
                     SNLHSIMMLLCKWGLS"
     gene            4332..4751
                     /locus_tag="PC512_000754"
     CDS             4332..4751
                     /locus_tag="PC512_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3785 domain-containing protein"
                     /protein_id="HDF2440524.1"
                     /translation="MSLYKFIYDDKEYLLKEENCSALINDEENPVQGVSISKIIDILN
                     EAEEVDFDVEYYQEACPLCLEGVKEKKKFFPFLEYHFYIFSKDGEYVISNISVDYKGL
                     SFNKLSRANKVDNSYIVSVIICENCQDYIVQIENCIV"
     gene            4882..6723
                     /locus_tag="PC512_000755"
     CDS             4882..6723
                     /locus_tag="PC512_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF2440525.1"
                     /translation="MEEIDDTILDSMFKLTLNERLLTNNDFIENKIDVVKNLIDCYKT
                     EQNSLMLLKSNFLLALLYGIQGFSEKMKEYILISCKYIDKCLPKDYKFLARFYSQIAI
                     LSLKNEDVNKANLYMDKFNLICDENNFLIEEIIFKSQLIYIKASKCIESSVIIKEIET
                     LYIKIKEINDFNCKKIYFFIIGKIYFLFLDDALIAKVNFLKARKYADLLKDMQVSSLC
                     NIKIGECECSFENYECSMEYFNEVISNKKYRNVNIIQKYRASNNITKILIKTRNYPVA
                     INNLAKSEVYLEKIKNHSLKEVEKFDLFISLAMYYAKSNEKSFEQSICYLDRAKNILN
                     MIKNIEEYIIYDLEIIYHQAKIYYIFGYYDNALNTNKKLLEKSKNAKNYNYVKLAYKS
                     IYLCFEKIQNYEMSMKYFKMYYELKMMYIKARNRNYIDSLNYRHEYIEKEINNMRKVK
                     LDLDKKKYVDHLTSAYNRTFLNDFLEKQEVSEYCTAFMIDVDYFKEYNDTYGHYNGDI
                     ALKNITIIIKKYLKKDMLMIRYGGEEFLILSVCKDYKKSKIFGRKLCRIVKKFLNNNL
                     TVSIGIDTCKNSSIDIKEIIENADKALYKAKESGRNRCLHYHDFKNF"
     gene            6750..8636
                     /locus_tag="PC512_000756"
     CDS             6750..8636
                     /locus_tag="PC512_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF2440526.1"
                     /translation="MKRSLIEDLKRNINKIEYDMLTKFYLNLTDLNYILDYHKDLLNT
                     KLEDNSRVYTLYLISLINYIKKDREASYNYLIESLKYIKKLSLKDDSDIISKIYIYLT
                     LSAISIRKYDKVNNFYFSAKKIIRQNHLNELLVLLNMSLCVEISALYQTKTDVIALVE
                     EVSFFKTLKNKALVSRANYIFGRVYLYLFNNFIKSMEYLIECLKLAQENNLYSIEAFC
                     KCIISLCYLESGNNVEAIKYINNVLDVAHSNNSISVTERVSIKIDLIWAYLKEDMNKE
                     AEVILLKTIKLMKVVEGVYKDYLYSFIFLYSAEIELKKDNCSFEKVNTYLILSKNIYK
                     SFGDVFIYNSKLDYIYKLYGDLYIKFGNIDEGISCYIKGLNLVKKSSLNLRKISIFYG
                     LIANGYELKKDFKLAIEYYKSMDWYSDRWEKNNSYKTSQAIHKQYELRQKQESLRLLV
                     DDNKKLENDILKDGLTKLYNRRYLEQQLDLFNETRDKNMVAILVDIDCFKSYNDNYGH
                     LAGDKVIVKVTDIIRSVFIDITEHIIRYGGEEILILVDSIESIGVEEIDNIELYIKRV
                     FKLLEFEGIEHIYSKIKNYITISAGVSIKRCRSRKDVEILIEDADKNLYKSKKAGRNQ
                     YIII"
     gene            8644..10644
                     /locus_tag="PC512_000757"
     CDS             8644..10644
                     /locus_tag="PC512_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2440527.1"
                     /translation="MILLRKKIGIIASDIELKERIEELYREDVENGTIIIDILNLDLM
                     ENQGRILVEKGAQAIIGRGGGYSLVIDTVNVPVIPMNMKSTDLLRAIEIAKKYSKKVV
                     LILGDNEVSFDYVGWRNVISTEITEEWFESKYEIRSKVVKYIDQKDEIVIVGGGLACS
                     FARQYGIDSVFATASDESIREAVEYCKKLLDTLGEEKFNNEVLRNILDGIKDGVIAID
                     SNGSIILYNESAKNMLKVERKCALNKYILDVFPKMEWMLDCLHEKEDVEDRKIRNINN
                     LIVNTRTTLIKVDNSTYGVLGIIQDITKLQNLERKIRFDLNQKGLYARYTFDDFLFKD
                     KLTKEFIEEAKKIGKSDYTTLLYGESGSGKEIIAHSIHNISKRKDRPFVAINCATIAE
                     NLLESELFGYEEGAFTGARKGGKRGLFELAHGGTLFLDEINSLSFNIQTKLLRVIEER
                     QIMRIGSDYIIPLDIRIIAATNESLTEKIVMGTFRADLFYRLSSLEINIPPLRDRRED
                     IIPLFNNFVNEVLKDDGLNGINSIDENFVLTKDEMDKLYNYSWPGNVRELKTIAQKYV
                     VTGKIKLRQDRDFKTKKLLPNSEVDKFNSETTASVEVQDESINISKINDGKISIDIKE
                     VNKYVEEKIISMLFAQGLSKNEVAQVLGISRTSLWKKYNKNI"
     gene            10906..12165
                     /locus_tag="PC512_000758"
     CDS             10906..12165
                     /locus_tag="PC512_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDF2440528.1"
                     /translation="MSQSMVGKHAMWPKENDVIFSISGRAQAAEKAFGMDNVINATIG
                     ALMDDSGKLITMKTVYEEYKALDNCEIGAYAALEGQPDYLEAVKKVFFRDYLPEGHIR
                     VLASPGGSGAIKLAVWNYTNEGDEVLTSDWFWSPYVSIAEEANRKVVNYQLFDENRRF
                     NFESFKEKFVNIAEKQGRVFTIINTPAHNPTGYSVADDEWDKILDLSKEVAKDKDKKI
                     IFFVDSAYIDFAGDDDVCRKFFKKFSNLPENVLVLVGFSMSKGFTAYGMRMGAIICIS
                     SSEDVAEEFHYSCVHSCRANWSNCNRSAMAVLSNIVNDPKKFKEYEDEKEIYKNMLTR
                     RADVFVKEAERVGLEILPYIAGFFVSIPCDNPKEVCEELTKHNLFAVPLKMGLRFAVC
                     AVSEDKCKKAPSIIKEALESLEVKINN"
     gene            12226..14013
                     /gene="iorA"
                     /locus_tag="PC512_000759"
     CDS             12226..14013
                     /gene="iorA"
                     /locus_tag="PC512_000759"
                     /EC_number="1.2.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indolepyruvate ferredoxin oxidoreductase subunit
                     alpha"
                     /protein_id="HDF2440529.1"
                     /translation="MKQLMTGNEAIARGAYEAGVKYASAYPGTPSTEILENIATYKDA
                     IVAEWAPNEKVALEAAIGGSIAGARTMASMKHVGLNVAADPIFTYAYTGVNGGMVLIT
                     ADEPGMHSSQNEQDNRMYAKFAKIPLFEPSTSQEAKDMIKEAFEVSEKYDTPVLYRVT
                     TRLCHSKGLVECYDREEVEIKEYVKNAKKMVTVPANAQIRRGVVEERMEILKKFSNET
                     DLNYYEINDTKIGVIASGMCCNFAKEVFGKNASYMKLGFTNPLPYEKIKEFAEKVDKI
                     YVIEENDPFIEEQIKAYGIDCIGKDVIPPYGEMTPDVLRKAIFGKTNDTIEYKSELVT
                     PRPPSFCAGCPHRGFFYELGKRKNLIVGGDIGCYTLGFAPPYNGIDYVVCMGSAFGTA
                     HGAQKVLNMKDDNEKRLVGVLGDSTFFHTGINGLLDVVYNRGNSISVILDNRITGMTG
                     HQENPGSGYTLQGAKTKEVDIEGLVKACGIEHVRVINPNNLKEVNEALDWALAIEDEP
                     SVIITRWPCVLKKFSKEDIEEFNNPFKTKCKVDHDKCIGCKLCLKTGCPALSFDKENK
                     LSNIDRNQCVGCGVCAQVCPKQAIVKEEK"
     gene            14015..14590
                     /locus_tag="PC512_000760"
     CDS             14015..14590
                     /locus_tag="PC512_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indolepyruvate oxidoreductase subunit beta"
                     /protein_id="HDF2440530.1"
                     /translation="MTKSILLVGVGGQGTILASKLLTMGLMEAGYDVKMSEIHGMSQR
                     GGSVSSQVRYGDCVHSPVIEIGGADILVSFEKMEALRWFNYLKPEGKALVNNHRIDSM
                     TVLIGGAEYQESDIDAELSRLNAKVINAADKAEELGNSKIMNVILLGCLVKSMQLESI
                     DWEKIISENVKPKFVELNIKAFHEGMEMVSK"
     gene            14643..15713
                     /gene="buk"
                     /locus_tag="PC512_000761"
     CDS             14643..15713
                     /gene="buk"
                     /locus_tag="PC512_000761"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HDF2440531.1"
                     /translation="MTYRILAINPGSTSTKIAVYDGEEQILVKTIDHPAEEIAKYNTI
                     QDQFEMRKEAVLNILKENSIDLKSLSAIVGRGGVLPPVKSGAYLVNEEMIDVLRHRPV
                     LEHASNLGAVVAHAISEPLGINSYIYDSVAVDELIDVARISGLCGMDRSSAGHALNTR
                     AMALKYAKDKGKDYKSLNLIVAHIGGGVSIYLHEKGRMVDMLSDDEGPFSPERSGRVP
                     ATKLVAACYSGQYSEREMTKKIRGKGGIVSYLNTVDAREVEKMIAEGNEEAKIIYEAM
                     AYQLAKGIGELATVVDGKVDAIIITGGIAYSEMFTSMVKKKVEFIAPVEIMAGENELE
                     SLAFGTLRVLNGEEEARIYSEN"
     gene            15931..16632
                     /locus_tag="PC512_000762"
     CDS             15931..16632
                     /locus_tag="PC512_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440532.1"
                     /translation="MGKISLKSMIRLFSGFFIFAISSVLMINAHVGLMPWDVLHQGLS
                     IKLGITIGQASIMVGVVIVILDAVFGENIGWGTLLNMTFIGIFIDLVIFSGVIPHASN
                     TYIGVFMVVIGIILAAIASFLYLGVCLGSGPRDGLMIALQKKTNKSVRLVRTILEILA
                     LVVGWLLGGSVGIGTLVSALGLGYVLQIVFRIFKFDTKLLKHRFIIDDIREWKEKKSN
                     EHKCKSSIVIKNEQN"
     gene            16692..17198
                     /locus_tag="PC512_000763"
     CDS             16692..17198
                     /locus_tag="PC512_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HDF2440533.1"
                     /translation="MELWDLYNADGIKTGNVIKRGNSIEEGYYHLAVEVWILNSNSQI
                     LIQKRSKSKKTLPNMWGMTTGCIVSGEDSLEGAIREAKEEIGIDITKDEMKVFRSMIH
                     EDTLWDVYLVKKEYDISKAILQEEEVSDIKWVSTDEIRQLLKEGLFFEYPEIYELLYE
                     IDNNKLNI"
     gene            17373..18395
                     /locus_tag="PC512_000764"
     CDS             17373..18395
                     /locus_tag="PC512_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDF2440534.1"
                     /translation="MEDNKGLARDSSKYKIVSISVVVIILITFWYMLNMVLLTFIMTF
                     IFYNLLVATRKRIKKFSSLNIPDSLIIIVLYALFAILLVLISYAVVPIIIVQLTELSR
                     VFSDFDVNQFAQSLGPKLYPIVSKLDFNKYISQAGLLIASTATKVGSFGVNILLAFLL
                     SLLLLLEKNEIKNFGDKLSDSKISFIYNSLVFFGKSFVKNFGEVMKVQVMIAFINSVV
                     SMIFLGFMGFPQIWALGFMIFVLGLIPVAGVIVSLIPLTVIAFNTGGITKVFGVLLMI
                     CIVHAVETYILNPKLMSNRTKLPVCFVFIILLVGEHYLGVWGLLIGVPIFMFLMDILG
                     VKFTSR"
     gene            complement(18542..18850)
                     /locus_tag="PC512_000765"
     CDS             complement(18542..18850)
                     /locus_tag="PC512_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1540 domain-containing protein"
                     /protein_id="HDF2440535.1"
                     /translation="MKNNNLNCAATNCAYNTSGYCYAGSIKVDGMQATTTENTYCASF
                     EDKYTSGITSRSNETNQVDTDNIHCEAVKCKYNKNELCKAEKVHINERNASCETFEMK
                     "
     gene            complement(18910..19338)
                     /locus_tag="PC512_000766"
     CDS             complement(18910..19338)
                     /locus_tag="PC512_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440536.1"
                     /translation="MNNKLHELEKNLPEISCSFCTHLSFKGPSLDYRYDIRCVISDTK
                     PDFRGCCEYFEPEYTELNTGDLDNLYINFLETCLKVNYNDYINSMYWKLFKERTLLEN
                     NFKCSICGSTENVDVYHVNKNLGRETSKDVVVKCDKCNCK"
     gene            complement(19561..21018)
                     /locus_tag="PC512_000767"
     CDS             complement(19561..21018)
                     /locus_tag="PC512_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation protein A"
                     /protein_id="HDF2440537.1"
                     /translation="MTTFLIGLAILLIGGALYGAYCEKVFGPDDRKTPALAQSDGVDY
                     VPMKKWKNSLIELLNIAGTGPILGPIQGILFGPIAFILIPIGCVFGGALHDYMSGMIS
                     IREKGAQMPSLISRFLGNKVFQVYNIFLCLLMLLVGAVFIYTPGDLVVTQILNMKSTI
                     NNPVVWIVYGLIFLYYLCATLFPIDKIIGKVYPIFGAILLLSAAGVGIGIFTQGYDLA
                     NLSLANWKGIHPDGIPLIPTFFVTVACGIVSGFHSTQATLIARSVSNEKEGKTTFYNM
                     MILEGLIAMIWAAAAMGIYNKGIPKELVGSPDVIGLVARDLLGSIGGIIAIIGVIVLP
                     ITSGDTALRSLRLMLADYFHYDQKEKKHRVILSICIFIPVIAILIFAKLSASGFNILW
                     RYFSWSNQTIAIFAFAMITVYLIIKEKNYIISLIPGMFYSFVIFSYIFNAQIGFNLNI
                     NISYVLAAIFTVLYAILTVRSGRKLKSKADTKLAD"
     gene            21436..22350
                     /gene="nadA"
                     /locus_tag="PC512_000768"
     CDS             21436..22350
                     /gene="nadA"
                     /locus_tag="PC512_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinolinate synthase NadA"
                     /protein_id="HDF2440538.1"
                     /translation="MDKDLTYQIKELKKEKNAIILAHFYQPPEIQELADAVGDSYYLS
                     EIARDCKEEVVVFCGVRFMGESAKILSPEKTVLMPVSNAGCAMADMVDEEGVIKLKQQ
                     YPNALVVCYINSTAKVKAHCDVSVTSSSAIKILENIDNKEIIFLPDKNLGGYIAEQFP
                     DKNFIFWDGYCKYHNNIRAEEIIELKDKYKNAEVLVHPECKKEIRDLGDYVGSTSGII
                     KYATNSKNKDFIIATEEGILHELKKNNPNKNFYIPGGKILCTDMKKTTLENLYSTLKN
                     MENEVIVEDEIMEKALNSLLNMHKLAEG"
     gene            22363..23664
                     /locus_tag="PC512_000769"
     CDS             22363..23664
                     /locus_tag="PC512_000769"
                     /EC_number="1.4.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-aspartate oxidase"
                     /protein_id="HDF2440539.1"
                     /translation="MNLEQDVLIVGSGVSGLYCALNLDKSLNVLVVSKSTIENNNTYL
                     AQGGISTARNIDDIESFVEDTMKAGQYKNRVEAVQVLADESIENVGQIVEYGMPLDKE
                     NGEIDYTREGAHSVNRIVHSKDNTGEVVFKTLLKEAKTRENITLIEDAYLLDILKDGN
                     KCIGARIFKSKKEIHVFSKIVVLATGGIGGLFKNSTNQRHLTGDGIAIALRNNIKIEN
                     LEYIQIHPTAFYEENNEGRRMLISESLRGEGAKLLNKNKERFVDELLPRDVVSKAIFE
                     QMEKDKLPYVYLDATHLDSEYLINRFSFIYNECLARGTDITKECIKVSPAQHYFMGGI
                     HVDLDSKTSMENLYAVGEISCTGVHGANRLASNSLLEGLVFSKRAAKNINSVIDNVKV
                     KFIDVPDMDIDIEQVKKENKILVIKEIERTSEDFGDELFDY"
     gene            23645..24481
                     /gene="nadC"
                     /locus_tag="PC512_000770"
     CDS             23645..24481
                     /gene="nadC"
                     /locus_tag="PC512_000770"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HDF2440540.1"
                     /translation="MNYLIIDRMIQDALIEDVPSEDITTNSIVDENSKSTVDLICKQD
                     GIIAGLGVFKRVFEILGDVDVKLYKNDGDRVKNREKIAVLTGSTRNLLVGERVALNYL
                     QRMSGIATITSRYVEKLEGTNTKLLDSRKTIPNLRILDKYSVKVGGGCNHRFNLSDGI
                     LLKDNHIGAAGSVKKAVELARKNTSFVRKIEVEVETLDMVKEAIEANADIIMLDNMSL
                     EMAKQAVDIINGRAIVEFSGNVNLDTIEDIGKIGVDVVSVGALTHSVKALDISMKNLR
                     NI"
     gene            24737..25069
                     /locus_tag="PC512_000771"
     CDS             24737..25069
                     /locus_tag="PC512_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HDF2440541.1"
                     /translation="MKVAYIFSSTNTHKILDKMIIPQLEQGTHGVDVLGMFFFMDNTL
                     FLSKGNPVGERLSKLHEKTDMIIMACDQCAIERGIENNLVDGATIGCFPNLYACLGSA
                     GVDQVITL"
     gene            25231..25416
                     /locus_tag="PC512_000772"
     CDS             25231..25416
                     /locus_tag="PC512_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440542.1"
                     /translation="MSEKYADKLEIKLYQAGKDFSYIKKYGIITKGTLIINQKKKYDR
                     LNKDTIERAIVEAINNN"
     gene            25443..26528
                     /locus_tag="PC512_000773"
     CDS             25443..26528
                     /locus_tag="PC512_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HDF2440543.1"
                     /translation="MNILEIVLNGVKDTIVASIVTLNGASGWLMISFILAGVLHNVLT
                     PRRFQKQLGNKKFSSLIKSTISGMFLPICSCGVIPLGISMYYSGAYLGPVLAFMTSTP
                     IINPIAVVLCLGLLGPKVTIIYLIAGFLVPFLVGFLGNCFGKEELSLHNDSEEEVIEL
                     EEEKRSFMENMIDGLKWSFGELALTISKYVVMGMVFAGFITTIFPNSIIQKYLGNPGL
                     LSLGSIAILACVMYVCAVGHIPFIAALVASGASPGIAITFLIAGAATNLPELISMFKL
                     IGKRTVIIYSVTLTLSSIIIGYITNLLLVNNNSVNLDATNSSIQLANKLMLNIPDSFE
                     YVCTILIILFAFKSIIPKMKEVIGNHA"
     gene            26521..26979
                     /locus_tag="PC512_000774"
     CDS             26521..26979
                     /locus_tag="PC512_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440544.1"
                     /translation="MLKKIVIISCIVVVLIILSKIVDDNIKEDASIPNVNKETLEYFR
                     KNYKEDIITCAEEDLNNDGKKDLVVIYKKSNNSNEMVVVVSDKNSHYITKPIPAPIEN
                     QTITFKNIDDKAPIEVIVSGSKNGNVGYAIYRVEGKKFVDLFGEDMDKCC"
     gene            27014..28105
                     /locus_tag="PC512_000775"
     CDS             27014..28105
                     /locus_tag="PC512_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2440545.1"
                     /translation="MKLSKKIQALILFGVMGTSILTGCSSKPKEKEEAKTGKDDYTIT
                     VGYYNCDHMTAGPVAESAGIYKDLGLNVKTVGNGKVPEAMAAGKMDAGYIGTKGLVGA
                     IPKGSPITIAANNHTGGSEYLIVSKDIKEPKDLIGKKIATDMSDFLWTSDYGPETGLP
                     TDPSKYEVVNMDSDKDKYLALKTGKIQAFTSCDPWGSVAENDGAGKIIASTQYKEKAN
                     GKEYNCCSFSLNKNFIKEHPDLAKKLVLAHTKAIEYIYTNPAEAAKIFAKYYNVEEEV
                     ALRTIYKKTVGEGRTLTWKVTGEEYKNNLQMYKDLKALDDIPKYEDTIDTSLLDSCGA
                     DDFDKFIKEKVNPEFPEGMSYEDWKAKVL"
     gene            28110..28334
                     /locus_tag="PC512_000776"
     CDS             28110..28334
                     /locus_tag="PC512_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440546.1"
                     /translation="MENMKNIIILFIIILGSIFIIFFNFEDKEEIKGKLRIGVSDDTS
                     GFVINYMVNRDYFENIKVSDIMDIFTINDC"
     gene            28344..28907
                     /locus_tag="PC512_000777"
     CDS             28344..28907
                     /locus_tag="PC512_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440547.1"
                     /translation="MQWALSSEEIDIAIICKDAAKQYVNVNSGFEIVGTVVQNSDIFL
                     LSDNNPEKIGVIQNRDYQSELVKKYYKNVEVAPLLGTALAYGLESNLVDGVVIDCIKS
                     IGLEGKRKSTTKLGDYDTYVLVVSKEFKKSKAYSDFITLYNKSVDALKNKATFKKALK
                     EYRNIRNIDMEEISNWKLKFLKIKAID"
     gene            28868..29497
                     /locus_tag="PC512_000778"
     CDS             28868..29497
                     /locus_tag="PC512_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2440548.1"
                     /translation="MEIKISKDKSDRLTKKKTDGSMDILYKIILLVIIFLVWHFAAKD
                     IGSSLLLPMPVDVIKGFFFCVTDAETVTNLFITLQRVLKGFMYALLFGLPIGFIMGFS
                     KTFERVLSPVVDSVRQVPIMAWVPLTIVWFGIGDGPTIFLIAFSGVFPIILNTIQGVR
                     AISKDYYNAARSMGASPIVIFTNVIVPASLPDILTGSRIAISTGWMSVI"
     gene            29537..29674
                     /locus_tag="PC512_000779"
     CDS             29537..29674
                     /locus_tag="PC512_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF2440549.1"
                     /translation="MVQAQTLMHTDVLIGLMIFAALIGFIIDRVLKFINKILCRWRFA
                     D"
     gene            29674..30426
                     /locus_tag="PC512_000780"
     CDS             29674..30426
                     /locus_tag="PC512_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2440550.1"
                     /translation="MKLSVRDINKTFVNNRVHTKVLEDISMDIDDGQFVCLLGPSGCG
                     KTTLLTIIGGFQKSERGDVFINDKRVKKPGIDRAFIFQNYALFPWKTIRGNVLFPMKQ
                     QKIPKEKREEMLEELLVMSDLKGKEKLFPHQLSGGMKQRVAMIRALACNPEVLLMDEP
                     LGAVDFQMRQNLQEELERIWIKKKITALMVTHDVDEAVYMSDRVIVMSRDKGRIIDDI
                     NIDIPRPRIRGSQKYEEYKNKLTDTLSKCYEV"
     gene            30439..30924
                     /locus_tag="PC512_000781"
     CDS             30439..30924
                     /locus_tag="PC512_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440551.1"
                     /translation="MSQIEKYNSLDNTQQKIRISIMDMIIDKGSSVTLQEVTEYISKK
                     LNIEKEYIERTLQYFIYKNIMVVDGNSINFIYPVSALPTNHKVTLRDNRSFSAMCAID
                     AIGTSCTFNQDIKINSICSATGKEIEVIIKNEKIEYVNNPNLRVLHINLDKHLNWAAS
                     C"
     gene            30931..31080
                     /locus_tag="PC512_000782"
     CDS             30931..31080
                     /locus_tag="PC512_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440552.1"
                     /translation="MNFFWTKSDFDAWTNEAGLSNDEDIYCLDINEAIVESYKIFKLK
                     QKVLS"
     gene            complement(31217..32038)
                     /gene="yidA"
                     /locus_tag="PC512_000783"
     CDS             complement(31217..32038)
                     /gene="yidA"
                     /locus_tag="PC512_000783"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HDF2440553.1"
                     /translation="MYKLIALDIDGTILNTQKRITPEVFESIQEAKRAGAKVVITTGR
                     PLPGVKELLNQLNLTDEGDYVICFNGAIIQEVKSEKIIHDVEMSLDDFDFIYNNVCKK
                     YKTKIHINTMTNLITPNETPGKYTLHEAKLNNIEVKYIQKDKIDESIKICKIMIVDEP
                     ERLEEIIQQLPKNLFNKYTIVRSAPFYLEFLGKTTNKGTALKTLCTNLNIPIENAIAV
                     GDEENDQHMIKYAGLGVAMGNARNSIKEIADYVTDTNNENGVAKVINKYILNKAI"
     gene            32531..34225
                     /locus_tag="PC512_000784"
     CDS             32531..34225
                     /locus_tag="PC512_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HDF2440554.1"
                     /translation="MKFSEFKYERPNYNSMKKEFLSCVEDINNSRNYKEQQKNIHKIN
                     LLRNKIETLSNIASIRYSTDTFNKFYKEEKNYWDEYMPLYEELNSYFYNAIVNSKFKY
                     DLIKEFGEQFFTIVEYSLKSFSKEIISELQEENKLCSEYTRLLASAEIMFDGKIRNLS
                     GMGKFMYSKNRKTRELANKAYYNFFEENETKFDDIFDKLVKLRDKMSKKLGFEDFVEL
                     GYVRMMRSDYREYMIKNVRKQVLKYVVPMANELYEKQAKRIGLEYLSYIDEGVEFLTG
                     NASLKGDSRYIIKNGKRMYSELSKETNEFFDFMLENELMDLETKKGKGAGGYCTYIPD
                     YKSPFIFSNFNQTADDIDVLTHEAGHAFQLYMSRWIDMPEINFPTLDSCEIHSMSMEF
                     ITWPWMDLFFKEDTDKYKFTHLSSSIKFIPYGVIVDEFQHYIYKNPNVDKSKRKEIWR
                     FLEKKYLPHRKYGDNSFLERGCWWFKQGHIFKNPFYYIDYVLAQICALQFWKKMIQDR
                     DAGWKDYINICKVGGTKSFLDIVSMGNLYSPFDDGCIESIIGDVKSWFDEINDSKL"
     regulatory      34557..34667
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            34771..35142
                     /locus_tag="PC512_000785"
     CDS             34771..35142
                     /locus_tag="PC512_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrdX family protein"
                     /protein_id="HDF2440555.1"
                     /translation="MIIITNNPKVKEEVQGREVLFKDTTYIGILEASRDLIHEGYELL
                     SHPLYGSVKPNETPYRTVILKKGNRLDINSLTLIEEAIITASKFQNNKKTPKWTESVQ
                     DDFRVIDYDIFYNTIQRMQYE"
     gene            35239..36186
                     /gene="trxB"
                     /locus_tag="PC512_000786"
     CDS             35239..36186
                     /gene="trxB"
                     /locus_tag="PC512_000786"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HDF2440556.1"
                     /translation="MENVYDLVIIGSGPAGLAAGLYGARAKLKTLILEKDKTGGQIVI
                     THEIANYPGSVPNATGPSLIARMVEQCKEFGAEMLRDNIVDTELDGDIKVLKGEKAEY
                     RAKAVIIGTGATPRKIGCPGEKELTGKGVSYCATCDADFFEDFEVFVVGGGDSALEEA
                     MYLTKFARKVTIVHRRQGFRCAKSVEEKAKANPKIEFLLDTVIEEIKGDGILESVVFK
                     NKVTGETHEYFADEEDGTMGVFVFVGLDAQTDLFKGKVDMDEKGYIITDEDMRTNIPG
                     VFAAGDCRSKTLRQVVTATNDGAIASIVAEKYIDEKFGN"
     gene            36290..36607
                     /locus_tag="PC512_000787"
     CDS             36290..36607
                     /locus_tag="PC512_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol reductase thioredoxin"
                     /protein_id="HDF2440557.1"
                     /translation="MLDLDKATFEEEVLNAEGFVFVDFWSEGCEPCKALMPDVHKLAE
                     TYGDKIKFCKMDTTKARRLAIKQKVLGLPTMAIYKDGEKVDEVTKDDATVPNIENMIK
                     KYL"
     gene            36876..38162
                     /locus_tag="PC512_000788"
     CDS             36876..38162
                     /locus_tag="PC512_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006439082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase component B
                     subunit"
                     /protein_id="HDF2440558.1"
                     /translation="MRLELGKIFIKDIQFGDVTEVKDGVLFINKQEMLQEIGGDEHIK
                     SIDIELARPGESVRITPVKDVIEPRVKVEGNGGIFPGIMSKVDTVGEGKTHALKGVAV
                     VTTGKIVGFQEGIIDMTGEGAKYTPFSKLNNVVVIAEPIDGLKQYAHEKAVRMIGFKA
                     AMYLGEVARNLTPDEVSVYETKPLLESIKEYPELPKVGYVYMLQTQGLLHDTYVYGVD
                     AKQIVPTLLYPTELMDGAIVSGNCVSACDKNPSYVHINNGVVEDLYARHGKDINFVGV
                     IITNENVYLADKERSSNWTSKLCKYLGLDAVIVSQEGFGNPDTDLIMNCKKIEMQGVK
                     TVIVTDEYAGRDGGSQSLADADVRADAVVTGGNANQVVVLPKLDKVIGHLEVVDVIAG
                     GSDGSLRADGTIEVEIQAITGATNETGFGHLTAKGY"
     gene            38274..38747
                     /locus_tag="PC512_000789"
     CDS             38274..38747
                     /locus_tag="PC512_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:38406..38408,aa:Sec)
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase complex
                     selenoprotein A"
                     /protein_id="HDF2440559.1"
                     /translation="MSLLSNKKVLIIGDRDGIPGPAIEECVKTVEGAEVVFSSTECFV
                     UTAAGAMDLENQNRVKDAADKFGAENVVILLGAAEAEAAGLAAETVTAGDPTFAGPLA
                     GVALGLSVYHVVEEPIKSLFDESVYEDQISMMEMVLEVEEIEEEMSGIREEFCKF"
     gene            38779..40089
                     /gene="grdB"
                     /locus_tag="PC512_000790"
     CDS             38779..40089
                     /gene="grdB"
                     /locus_tag="PC512_000790"
                     /EC_number="1.21.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:39826..39828,aa:Sec)
                     /transl_table=11
                     /product="glycine reductase complex selenoprotein B"
                     /protein_id="HDF2440560.1"
                     /translation="MGKLKAVHYINQFFAGIGGEEKADTKPHVAETLPPISLQLDKLL
                     GEDIEIVGTVVCGDSYFNENIDSASEEVLSMVKGFEPQLFIAGPAFNAGRYGVAAGTI
                     TKVVKDALNIPALTGMYVENPGADMFKKDVYVVETSDSAAGMRKALPKIAKLAVKLAN
                     GEEIGTPKDEGYIARGIRVNYFHEDRGSKRAVDMLVKKIKGEPFETEYPMPNFDRVDP
                     SKAVKDLSKCKIALVTSGGIVPKGNPDRIESSSASKYGTYSIAGVMDLTEETYETAHG
                     GYDPVYANLDADRVLPVDVLRDLEKEGVIGKLHETFYTTVGNGTSVANSKKYASEIGA
                     ALVADGVDAVILTSTUGTCTRCGATMVKEIEKTGLPVVHMCTVVPISLTVGANRIVPT
                     IAIPHPLGNPALDPTEEKALRRGLVEKALNALTTEVDGQTVFEK"
     gene            40345..41877
                     /locus_tag="PC512_000791"
     CDS             40345..41877
                     /locus_tag="PC512_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014520415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III family protein"
                     /protein_id="HDF2440561.1"
                     /translation="MTYPVLKGAGYVLIHTPDMIVQNGSTCTVERATNPDSEFLKEVS
                     NHIRSYEDVVNYMPNQVYIGNRRPEELRDLPMPWCEQKIEGTRNGKFGEIMPQDEFIA
                     LMQISDAFDLVKLSQEFIDEVKPKIENNYPEIAPFVGKLKGDDIEEGKELVATHIAEG
                     LYHDGKFVGYVKRAHDVDVNLNAHTMFENLVVKASGVLSAIQMLRHSKIDPAEIDYVI
                     ECSEEACGDINQRGGGNFAKSIAEIAGLQNATGSDTRGFCAAPTHALIQAAALVKAGI
                     HKNVMVVAGGASAKLGMNAKDHVKKGLPVLEDVVGGFAVLVSENDGVNPVIRTDLTGK
                     HTVGTGSSPQAVMTALITSGLDRANLKITDVDVYSVEMQNPDITKPAGAGDVPEANYK
                     MIGALAVKRGDLEKKELKDFVSNKGLPGWAPTQGHIPSGAPYIGFLIDDLTTGNRNRA
                     MIVGKGSLFLGRMTNLFDGVSFIAERNTGVTEETSGISKDEIKKIIAESMKKLALDML
                     EE"
     gene            41888..43033
                     /locus_tag="PC512_000792"
     CDS             41888..43033
                     /locus_tag="PC512_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine reductase"
                     /protein_id="HDF2440562.1"
                     /translation="MSKKVIADVFLEVANAIESGEFGKKVKIGVTTLGSEHGVENMVN
                     GAQLAKSNLFDIVLIGPKVETDLEVVEVNDEKEMHAKMEELLDSGYIDACVTMHYNFP
                     IGVSTVGRVITPAKGKEMILATTTGTSATNRIEAMVRNAIYGIATAKSMGNKCPKVGI
                     LNVDGARQVEKCLKELKDNGYDMEFADSIRADGGCVMRGNDLLVGAPDVMVTDTLSGN
                     IFMKVFSSYTTGGDYEAQGFGYGPGVGEDYDRKVLIVSRASGSPVVANALKYAYDVVK
                     GDISNVARNEFAKVKKAKFDDIISSLTKKEVKAEKVEVKMPDKEIVTRQIAGVDIMDL
                     EDAVSELWKNGIYAESGMGCTGPIVLVNEAKGDLAVETLVKAGYTAK"
     gene            43343..44422
                     /locus_tag="PC512_000793"
     CDS             43343..44422
                     /locus_tag="PC512_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDF2440563.1"
                     /translation="MSRVKNVVELLETKGVDALYLTKKTNVNYISGFPDEEAYAVICK
                     DGNFLVTDSRYMELAEKVCKDFEIINWHNFDRSVAKAVKSVCDKVGIKKLGFERTNIV
                     FDKYEELKNLIEKDNGELIPTENIVETLRYVKDKDEIKNTRKACEIADKALEELIPHI
                     KAGVSEIELATRLEYFMKMNGAQNIGFETILISGAKTSLLHGKPSDKIIEKGDFVLID
                     YGAMYNGYISDTTRTFIVGGASEKQLEIYNLVKEAQNVGVENMKAGVHATIPDAEIRK
                     VVKKYEDYYYQGIGHGVGRDVHEEPFIGNYGDKIIEEGCIITMEPGIYFPGWGGVRIE
                     DTVLITKNGPERLTKFPKDLMILDK"
     gene            44535..45134
                     /locus_tag="PC512_000794"
     CDS             44535..45134
                     /locus_tag="PC512_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440564.1"
                     /translation="MYKKHKFIKNIKKAWYKIKLIDRCLIIVMAILMFQSIYNLFVNE
                     VNSQDTTTIDVVVRTTSAAIFGYFLSANFIKRPLRKYTNTDVSSNLFIDNNLSPKGQE
                     SNQNNIMNVKNTIGFTSEADNYEKKIPINNNEGFEEGETSELQIIIATVICIVALTVL
                     FVVRNFTTTTSASLGTISQMRDFVSGCVGFLLGCPSKPD"
     gene            complement(45321..46193)
                     /locus_tag="PC512_000795"
     CDS             complement(45321..46193)
                     /locus_tag="PC512_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF2440565.1"
                     /translation="MNINYLYYFQTVCKYKNMTKAAESIHISQPSITLAIKELEKELG
                     FELFYRIGNKIELTPEGKIFLDKSKHFIKQFEDFQCDALDLGKKRKASLKIGIPTVLG
                     TFLLSKILPRFNVIYPDIELKIFEVPTFVGAKMIEESTLDFCIGIIDSDIYDDIDSKT
                     IYKTELYLVTNPKNELAKHPIISNYMLKNVPFVILSEGSYHYKIITKRLEKAKPNIIL
                     HSNQLSTIRYLLENDLASTILYKEIFQNTENLCSIPLERAITANIGVLWRRNQYISHS
                     MKLFIEYMASIHIN"
     gene            46610..48013
                     /locus_tag="PC512_000796"
     CDS             46610..48013
                     /locus_tag="PC512_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440566.1"
                     /translation="MKGSDLVKFELMDFLMNPFVLMFAAVITGILFGKIKFGKFNFGV
                     SGALFTGLFIGWLAYSLGNLIIAKGETAAGYKAATVMMGNGIISSDFFDFFLIIFVAA
                     VGLLAAKDMKAVLKKYGARFVILGVLITFIGGSMTYAMTLLSSDKGSSAYEVSGVYTG
                     ALTSSPGLAAALETAGKHAEDVSKEFEKASIKDKKEILKVVDPEGKLDVNTTTSLTQE
                     QIDKYIAYAEAGVGIGHAVAYPFGVLIVILGVNFLPKLFRMDLKEERRKYEKEMKEAR
                     DSVSGKTIPEVPFNIITFFLTCLAGYLVGGIHVFMGPLGYFTLGATGGSLIVSLVLGY
                     IGKIGVVNFRMEEKVLNILKQIGLVFFLAIVGLRYGGKVVDSIMTSGMHLALVAIAVG
                     VTAMMIGFLVGKYVFKLNWILLSGAVCGGMTSTPGLGAAVDALDSDDPAAGYGATYPF
                     ALLTKVILVIVLHKLPM"
     gene            48040..49584
                     /locus_tag="PC512_000797"
     CDS             48040..49584
                     /locus_tag="PC512_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase/transferase family protein"
                     /protein_id="HDF2440567.1"
                     /translation="MNNEGAFEELSGRLRNKELCDLIMNADEAAKIIEDGMVIGVSGF
                     TPSGYPKAVPLAVSERAKSGEKIKLTVYSGASLGPEVDGAWSEAGIIERRLPYQTNSI
                     LRNNINKGVVDYIDMHLSHSTQFLNYGTIPKVDVAIVEALAITEEGNIIPTSGIGNSP
                     SFIKSADKVIVEINLAKPMEMEGMADIYITENPPNRKPIEINHPKDRIGTTYIPCGLD
                     KIAGVVITNMQDKTRPLGVVDEASKKISNNIIAFLREEVKSGRLSKNLLPLQSGVGSV
                     ANAVLYGLCESEFENLTCYTEVVQDSMLDLIRMGKVTMASTTSVSPSPEGLIKFEKDI
                     DFFKDKIILRPQEISNNPEIARRIGVIAMNTAIEVDIYGNVNSTHIMGSKMMNGIGGS
                     GDFARNGAITIFSTESIAKNGDISSIVPMVSHVDHTEHDVMVIVTEQGYADLRGLAPR
                     ERAIKIIENCAHPDYKEQLRDYLNRACKSGAKQTPHILDEALSWHSKFMSTGTMKKAE
                     TFKSAL"
     gene            49615..51006
                     /locus_tag="PC512_000798"
     CDS             49615..51006
                     /locus_tag="PC512_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="HDF2440568.1"
                     /translation="MEKAVENFEDLSKEYINGYIERARKAQREFECYTQEQVDKIVKI
                     VGKVVYYNAEYLAKLAVEETGMGVYEDKVAKNKSKAKVIYNNLKDKKSVGIIDIDRET
                     GITKVAKPVGVVAAITPCTNPIVTPMSNAMFALKGRNAIIITPHHKAIGCSTKTVEMI
                     NEELEKIGAPENLIQILDQQSRENTRNLISSADVVIATGGMGMVKAAYSSGKPALGVG
                     AGNVQCIIDRDVDIKEAVPKIIAGRIFDNGIICSGEQSVIVAEEMFDKIMDEFKNNKG
                     FIVRDKVQKEAFRNAMFVNKSMNKDAVGQSVHTIAKIAGVEIPEDTKIIVIEADGPGE
                     EDIIAKEKMCPVISAYKYKSFEEGVAIAKANLNVEGKGHSVSIHSNTVKNIEYAGENI
                     EVSRFVINQCCATSAGGSFFNGLAPTNTLGCGSWGNNSISENLDYKHLINISRIAYYM
                     PENEVPTDEELWG"
     gene            51199..52695
                     /gene="abfD"
                     /locus_tag="PC512_000799"
     CDS             51199..52695
                     /gene="abfD"
                     /locus_tag="PC512_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybutyryl-CoA
                     dehydratase/vinylacetyl-CoA-Delta-isomerase"
                     /protein_id="HDF2440569.1"
                     /translation="MALMTGAQYIESLRKLNTKVYMFGEEVKNWVDHPMIRPSINCVA
                     ATYDLAHDPEYADLMTVTSNITGEKINRFGHLHQSVDDLIKKVKMQRLCGQKTASCFQ
                     RCVGMDAFNAVYSTTFECDKAHGTNYHDNFVKYLTYIQENDLVVDGAMTDPKGDRSLS
                     PSAQPDPDMFLHIVERREDGIIVRGAKAHQTGSINSHEHLIMPTISMTEADKDYAVSF
                     AVPSDAEGVFMIYGRQSCDTRKLEEGADVDLGNKEFGGQEALVVFDNVFVPNDRIFLC
                     GEWDFSGMLVERFAGYHRQSYGGCKVGVGDVIIGAAALAADYNGANKASHIKDKLIEM
                     THLNESLYCCGIACSSEGHKTEAGNYQIDLLLANVCKQNVTRFPYEIVRLAEDIAGGL
                     MVTMPSEKDFKSDLKVGTSGMTIGEVCNKYFKASSVASTEERMRILRFLENICLGSSA
                     VGYRTESMHGAGSPQAQRIMISRQGNINQKKELAKKIAGIKKEEALNL"
     gene            52830..53105
                     /locus_tag="PC512_000800"
     CDS             52830..53105
                     /locus_tag="PC512_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440570.1"
                     /translation="MTCGVRFCGGCNPRYERGKALTIIKEHFNGRVDFSIAQENVEYD
                     LLLIIGGCATLCASYQQYKVKNECVKMWDFSHIERVINVIESAICET"
     gene            53129..54436
                     /locus_tag="PC512_000801"
     CDS             53129..54436
                     /locus_tag="PC512_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase/transferase family protein"
                     /protein_id="HDF2440571.1"
                     /translation="MSWQELYQSKLCSATEAVKQIKNGDTVVFAHCVGEPPALVEAMI
                     ENAEQYKDVEIKHMVSLGSGGYTAKGMEAHFRVNPMFVSGNVRKAIENGDGDFTPAFF
                     HEVPKLLREKRLKCDVVLAQVTPPDEHGYCSLGTSVDYTYEAIKTARTVIVQVNDQFP
                     RTYGEVVHVSEFDYIVEKSQPLFELQPAKIGEVEEAIGKNCASLIEDGSTLQLGIGGI
                     PDAVMLFLTDKKDLGIHSEMISDGTLALYEKGVINGKYKNFDKEKMTVTFLMGTKKLY
                     DFANNNPAVEVKPVDYVNHPAIIMKQHKMVSINSAIQVDLMGQVVAEAMGLRQFSGVG
                     GQVDFIRGVSMGEDGKAIIAMPSITTKKDGTVISKIVSIVDEGAPITTSRNDVDYIVT
                     EYGIAELKGKSLRERARNLINIAHPSVRESLAVEFEKRFKEKY"
     gene            54456..55574
                     /locus_tag="PC512_000802"
     CDS             54456..55574
                     /locus_tag="PC512_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybutyrate dehydrogenase"
                     /protein_id="HDF2440572.1"
                     /translation="MEALRVVPKIFYFDTFKEFNEEFKIGKNDLVITNEFIYEPYMKP
                     LGIDTNLIFQEKFGTGEPSDEMIDSMTKEMKKYNFDRIIAFGGGTIVDICKILALDVP
                     EKSIDLFEGEVSPKKVKELVVVPTTCGTGSEVTNVAIAELKSKHTKKGLAVEETYADY
                     AVLIPETVKGLPYKFFVTSSVDALIHAIESYLSPKASPFTEMYSLQAIKMIMDGYKKI
                     VDKGEEERFNHLRDFVLASNYAGIAFGNAGCAAVHALSYSIGGAFHVAHGEANYQFFT
                     EVFKMYSRKKPNGKIIKCTKILADALECDPNCDVYGELEKFLNKLIAKKALREYGMVE
                     SQIDEFTDSTIANQQRLLANNYVELSREEIREIFANLY"
     gene            55861..56781
                     /locus_tag="PC512_000803"
     CDS             55861..56781
                     /locus_tag="PC512_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HDF2440573.1"
                     /translation="MYKSENFSKKSVLINSFLSKFLKIIGWGLVSLFTLSALVLSTIS
                     IIIGWAVILPIQVCAVFLLIGGVCIFKGKRLGDQISRYKKYCTIINNRNIIPVELIAE
                     NTSKSLNFIIKDVQKMIDKNYFINTYIDKRNNQIVLTNEDFVPPRYEDVAYEVKEEEK
                     TDESNEVDTIINKGMNYLTQIKEANKNIKSESMGDKIVQVEDVTSKIFDVVKHDPSKL
                     TQIQKFMDYYLPTTLKLLNSYHTLEEQGIDRENITTTMESIENTMNTIVVAFENQLDY
                     LFEDEAIDISTDITVLENMLVQEGLTSGKF"
     gene            56896..58053
                     /locus_tag="PC512_000804"
     CDS             56896..58053
                     /locus_tag="PC512_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HDF2440574.1"
                     /translation="MNNLDDIPVMPTLTLDPFGEESNTNDIDNSDLLMKKDEKDPEEE
                     KLSESERKMVKEFAEKIDITNTNMILQYGAGAQKKVASFSETALKSVKTRDLGEVGDM
                     LTNLVTDLKAFSADEKEQSGFLGIFKKANNKISNLKTKYDSAEVNVDKVSKELQKHQV
                     KILKDIAMLDKMYELNLAYSKELTMYIIAGKQKLKDMKEYEMPKLREKARLSGSTEDA
                     QSVNDMVSLCDRFEKKIHDLELTRMVSLQMAPQIRLVQNSNNLMAEKIQSTIVNTIPL
                     WKNQIVLALGISHLNQAMKAQREVSNMTNELLLKNAETLKMGTIETAKESERGIVDID
                     TIKKTNQSLISTIDEVVKIQHDGRIKRQEAEVELSKIENELKSKLLEFTVK"
     gene            complement(58134..59030)
                     /locus_tag="PC512_000805"
     CDS             complement(58134..59030)
                     /locus_tag="PC512_000805"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HDF2440575.1"
                     /translation="MLKKVKYPIGQVKVSDKFKTIKLLSRKYSISSMCKLISVSRSGY
                     YKWLSYSKKSSDRGIKDRIIKDYIIEIHKKYRGTYGRKRICTYLNKILDTPINHKRVY
                     RLMKELGIKSIIRKKVYRRKFKSYEIYDNILNREFRANQPLEKICMDITYIPIGKKFL
                     YMNVAKDLFNGEIVAYEISTKMDTKLVNNTVNQLINMNLAKDCILHTDQGSQYTSRSY
                     SKRLKDNGIIQSMSRRGNCWDNAPIESFFSHFKSELIYLIDTTDPKEMISLINDYIYF
                     YNNERIQLKNGMSPIEYRTHSE"
     gene            complement(58988..59305)
                     /locus_tag="PC512_000806"
     CDS             complement(58988..59305)
                     /locus_tag="PC512_000806"
                     /inference="COORDINATES: protein motif:HMM:NF013677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF2440576.1"
                     /translation="MSKKHKKYSKELKLKAVNLYIKEGYSSYKIAEMLNIRSKTQVQN
                     WVKDYKNKGKTAFDDETRGRFKNISLENDNRKFKSVEEELKYLRMENEFLKKLSTLLD
                     KSK"
     gene            complement(59442..60941)
                     /locus_tag="PC512_000807"
     CDS             complement(59442..60941)
                     /locus_tag="PC512_000807"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HDF2440577.1"
                     /translation="MAFYFDTPSHTFSEYLLVPGFSSTDCIPANVSLKTPVTKFKKGE
                     EADIYMNIPLTSAIMQSVSDDKMAIALAKEGGISFIYGSQTIEDEAAMVARVKSHKAG
                     FVVSDSNIKPDNTLKDILDLKEKTGHSTVAVTEDGTSTGKLLGIVASRDYRISRMDLD
                     TKVSEFMTPMSSIVYANKDVTLKEANNIIWDHKLNSLPVLDDNGNLMYMVFRKDYSSH
                     KENPLELLDSSKRYVVGAGINTRDFAERVPALVEAGADVLCIDSSEGFSEWQKITLDF
                     IREKYGDTVKVGAGNVVDREGFLYLAEAGADFVKVGIGGGSICITREQKGIGRGQATS
                     IIEVAQARDEYFEKTGIYIPICSDGGIVYDHHITLALAMGADFIMLGRYFSRFDESPT
                     NKVNINGSYMKEYWGEGSARARNWQRYDLGGDKKLSFEEGVDSYVPYAGSLKDNVTLS
                     LSKVRSTMCNCGALSIPELQKNAKLTLVSSTSIVEGGAHDVMLKDNRNL"
     gene            61537..62961
                     /locus_tag="PC512_000808"
     CDS             61537..62961
                     /locus_tag="PC512_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICB"
                     /protein_id="HDF2440578.1"
                     /translation="MSSSNQSTIKTSIQRVGKFLSGMVMPNIGAFIAWGLITALFIPT
                     GWMPNEKLSTIGDPMIKYLLPLLIAYTGGKAIAGQRGGVIGAAAAMGVIVGADIPMFI
                     GAMIMGPFAGWVIKKFDKFVDGKIPTGFEMLVNNFSIGIIGMLLAILGFYAIGPAIVA
                     GTALIESGVQFIVSKSLLPLVSVFIEPGKVLFLNNAINHGILGPIGIAEAKEAGKSIM
                     FLLESNPGPGLGVLLAYWMFSRGSVKQSAPGAVIIHFFGGIHEIYFPYILMNPVLILA
                     TMAGGAAGILTFSILGAGLVAAPSPGSIFALMALAPKGGLLPVLAGVAVATVVSFLVA
                     APFVKRASANESEEDSTSLEEAKAKMSDMKSASKNSEKNIEKKQLEVNEIKKIVFACD
                     AGMGSSAMGASRFKNRIKNLDLDIEITNSSVDNLPDDTQIVVTHNTLVERVAKNNSSV
                     EIVSINNFLNDPNLDTLFKRLESK"
     gene            62996..65125
                     /locus_tag="PC512_000809"
     CDS             62996..65125
                     /locus_tag="PC512_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HDF2440579.1"
                     /translation="MKKKKITSRQKKIILMIVENSKKNIPITISEIAGTLELSSRTVL
                     RDMSGIEKWFDENDFNFVKKPGVGLILEENIENQNFIIELLEEEKIEKEYSKEERNLI
                     ILSKLLVSNEPVKSYYFAKILKVSEGVLNNDFSLASKWLERFDIELVRKPGLGVYLKG
                     QEKSFREAYVNLIYDSFNEKEILDMVRNISENIQTDKAIEILSENRLLNLMDRCIIIK
                     VEATLTKKLSDLDVNLADSAYIGLVVHISLALQRIKNGENITMDKEFLKELSITEEFK
                     LAKEIVKGMETDFNMDIPVDEVGYITMHIRGAKQRSSSNHKALNLDDIEIMEITNKMI
                     DLAEDEFKISLKNDERLFKDLANHLGPSINRLNMGLEIRNPLLDEIKSKYSYAYDGVE
                     KISRIIKDKLNINSIPESEIGYIAMHFASAIEKNLMMNTNINIVVACPTGIGTSRFLS
                     TKIENKFPNLNILETISAINIDEEYLKGKDVDLIVSTVELNTSLNYICVGPFMSLDDE
                     QIIKEKIKSIAQNKLINLNTKNDTKSKNKVYEQITESMNIGKDILQFLEEIRFEKFES
                     KDLSELIEDSSKIFAKSSEDIMSIKESLKERLKISIPYIEESKILLLHCMSERIDIMK
                     LSIIKLENRIVLDSNEEIDNVVFMLLPKNSPSYQRQIMSEISGSLIDNIIFTNKINKF
                     SIEEMTLEVKDIVFNFYTNRLKAFIDE"
     gene            65155..65577
                     /locus_tag="PC512_000810"
     CDS             65155..65577
                     /locus_tag="PC512_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2440580.1"
                     /translation="MSKVLNENNIFLGLDSVSKEEAITLAGRKLVENGYVKEEYIPAM
                     LEREKVMTTYMGMGVAIPHGVNEAKKEILSSGIVILQFPNGIDFDGEKAYLLIGIAGV
                     GDEHLEILSNIAVVLDDDLTERLKNSNDKQAFMEAFAK"
     gene            65596..66747
                     /locus_tag="PC512_000811"
     CDS             65596..66747
                     /locus_tag="PC512_000811"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HDF2440581.1"
                     /translation="MKKAIQFGAGNIGRGFIGGLLVKSGYHVVFADVNEEILNSINKD
                     KKYTIHIRDVECIDEVIDNISAVSSIKEEIIDEIVQAEIITTAVGPLVLTKIASTIAK
                     GIKARKEKGLTSNLNIIACENAIYASSSLKEEVLKYLNKEEVEYLEIYVGFPNCSVDR
                     IVPPGKNENPLDVTVENFYEWNVEKQGFKGEIPTIVGMNLADNLMAYIERKLFTLNTG
                     HAITAYIGYLKGYKTIEESIKDKFICDIVKSAMVESGEGLIKKYNFDSEAHYKYIDKI
                     LNRFKNPYLNDDVLRVGREPLRKLSDKDRLIKPLMTAKSYGLSVDNLILGIGAALHYN
                     NSEDTQSVELQELIKSNGVKKAVAKIANISNDEELLNNIEKSYIFMKNL"
     regulatory      66853..66954
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            67137..67709
                     /locus_tag="PC512_000812"
     CDS             67137..67709
                     /locus_tag="PC512_000812"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HDF2440582.1"
                     /translation="MKALQEKILREGSVSGNDILKVDSFLNHQIDVAFLNEIGREFKE
                     RFKEEKVDKIFTIEASGIAIASIVSQYFDNAPVVFAKKSESKNLDKDVYETNVYSFTK
                     AREYSVKVSKKYINKGENILIVDDFLANGRAALGLKDLIEQAEANLVGVGIVIEKGFQ
                     AGGALLKANDVRLESLAVVESIDNGTVKFR"
     gene            67773..68423
                     /gene="fsa"
                     /locus_tag="PC512_000813"
     CDS             67773..68423
                     /gene="fsa"
                     /locus_tag="PC512_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HDF2440583.1"
                     /translation="MIFFIDTANIEEIKEANDLGVICGVTTNPSLIAKEGRDFIEVVK
                     EISEIVDGPISAEVISLEHEGMIEEAEKLSKIHKNIVIKIPMTAEGLKAVKVLSSKGI
                     KTNVTLIFSAGQALLAARAGATYVSPFVGRLDDISQNGLDLIEEIVDIFSVNSIEAQI
                     IVASVRNPIHVLQAARMGADIATVPLKVINQMIKHPLTDKGIDSFMKDWEGASLKL"
     gene            68575..71499
                     /locus_tag="PC512_000814"
     CDS             68575..71499
                     /locus_tag="PC512_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2440584.1"
                     /translation="MDKILREIQREDKKNPYTDQELAEMLNVARSEVISVRKKNNILD
                     SRERRKKILIKDISKIVSENPQMSERKITEILIENGYNISRSAVSKLLKEENLNQSKI
                     GIKDKEPASSGKYVKVSKVVEEDGFEELIGIKGSLKEKVNLAKSAIMYPPNGLHTIIY
                     GETGVGKSELATCMYKYAIKNNIKEENSPFIVFNCADYAENPNLLIAQLFGVVKGAYT
                     GADANREGLVEQANNGILFLDEIHRLPAAGQEILFSLIDRGEFRRLGESSSNRKANVL
                     IISATTENPDSNLLQTFRRRIPMVINLPNMSERPKSERYEIIIKFFEREAKRVNKNFI
                     ITKEVMCALMNYKCTGNIGQLKSDIQVTCARAFSKSIFSSDKVIIDLDSLRDYIKSGY
                     YDCNCKNEKYSEFSVEDIYIDISELVSGKNRILSDNEISEIYNYAEKELKVLESKCFS
                     EEELKNAFIEKLDKKFNAIKNNKNLSDRRSRIDWGGQLKESTLEIMDKVIVFIKEQFK
                     HVNQGLYLALAIHIEHAIGRIKDGKTIINPSLDKIKASMPMEYELSRYIMGIVEDLTQ
                     VTFPEDELGYLAYYINKFCYNEESIKDKVKVVIVTHGKVGIEMSKVVNHILGIECTLG
                     IEIALTDSPSEGIEHVLEELQKIEARKGILVLIDMGSLVILGDEVEKRLGIRCKTVNR
                     VDTLLAMEAGKLATIEGKSLDGIIADLKKNKNYAMINTNKFSYRKNEYGKKNVIITLC
                     LSGVGTALNLKEHIEKQIKEYDTLIEVKPVAFLNNNLEEELNDIEAEYNIIAICGTID
                     IDYKNVPFISYNEVLGKNGINKVLEHLNSKQPVLNIENQLNNLIHEDLILYNFEGISK
                     EYIIDTLVSKLEEGGYVDSKYILSVYKREAMGSVVMASKVAVPHGLPENVIKPAIAIA
                     RLNKPIVWDNKFMVDLVVLLALKENNKKEIRSLFSKINDQHTLEVLLNTEDKNEIKEL
                     LS"
BASE COUNT        28158 a         7834 c        12830 g        22862 t
ORIGIN      
        1 atattccttg tgtgaaaata taggaatttt tattaaatag ttttaatgtg taaataacat
       61 tctacactat tgtaattaaa tatgtaaaaa gtaaaatatt taaatagata tattttaaaa
      121 tctaactttt aatattgtaa aaaaattaga aatttaacaa aaagtacaaa aattcacatt
      181 tttttcataa agtgtttgac taaaaaattc acatgttgta gaattaaggt agcaggagtt
      241 ttgagggagg tgtaaataat gataagaaaa ataccacaag cagaactaaa agtaatgaaa
      301 ttcatttgga aagtagatgt tacagtgaca tcaaaagatg ttattgaagc tatggaacaa
      361 aaatatggct ggaaacaaac caccacactg acacttttat ctaggctggt aaaaagagga
      421 ttcttagatg ctcaaaaaat agacagatat acacattaca caataagagt aaaacacaaa
      481 gattatttaa gttttgagac aaaggatttc ctaagtaata tacatgatga ctctttaaga
      541 agcttaattt cagcattaca tgatgatgaa aatataggta aagataagct agattttcta
      601 gaaagttatt ttgataattt aaaggatgaa taattatatg ctatatgttt ttgaaaatct
      661 tataaagaca actattgtat gtagtcttgg tatttgtcta ttattatttt tgaaaagata
      721 tttatttaag aagtttagta agagattcaa ttattatatt tggttgataa tagtctttag
      781 aatgttactt tttctattta attatacaat agtgtatgaa gtaaaagaac ccaaagaaaa
      841 tgcattagga aataatatta cacaaattga tatttctaca gataataatc ttatgctgta
      901 tgtagcttat ttatggttat ttgtaactat agtcattgca gtttatacat ttataaagta
      961 tacaagattt aaaaatctag ttgttgatgt atcttatgat attgaagata atgatataaa
     1021 ctgtatctac aaaaacttgt taaaagaatt aaatataaaa aagaaaattg aattaagagg
     1081 ttctgatgaa ttgataagtc cagcaggtat gggattattt aaatcttaca tattcttacc
     1141 agactatcct tatagtaaag atgaactaac ttggattttg aaacatgaat taatgcattt
     1201 taaaaataaa gatattttaa taaagttttt agttttgtct gttagaataa tatattggtt
     1261 taatccactt gtatatgtaa tgagcaataa agtaaatcta gattgtgaat tatgttgtga
     1321 tgaaagtgtt ttggtagaat gttctttaaa agataaaaaa gaatatgcac tagcacttat
     1381 aaagtcaatt aagtttagta aaaattataa tagtaagatt ttgacaaccg agtttgataa
     1441 gacaaatttg gaaaagagac ttgagagtat tgttaaaaag aaaggcaaaa gtggaatact
     1501 aattgctgtt ttagtattta tgacttctat aacatctttt gttgaagttg atgctcaagt
     1561 tagaattgat gagggtaata atggaatgaa taacaatatt aatgaatttt tattgaataa
     1621 gacgactgat aaaattataa atatttatta taaagatgca ccaaatgaaa ttaggaaatt
     1681 ttatgaagat aaatgcgaat tagaaggtaa aatacctaga gactatgaca taatagaaat
     1741 ggatatgaaa gattataatc aattaataaa ataattataa ggaggatttt atgttaacaa
     1801 aattaagaaa aatagtagct attatgtgtt gcttattgct tacttttaca agtgtggcat
     1861 ttgctgacac aagtaaagag aaaggaggaa gtaaagagac tgttccagag aaaaacctag
     1921 attcttttac tctttctggg tatatatata catatgaaaa tgcgccacaa gaaataagag
     1981 atgaacataa acaaaattgt gaagagataa atatagaccc taagccagat gatgagatat
     2041 ttgttccaga atcagctaat ctaatgaatg aggacaatag taaaggtgtt tatgcaagtt
     2101 atactgtttc ttataatata ggtgctaaaa ctataacaat tatgagtaat gagtatttga
     2161 ctataagtac aacaaaagtt atacgaaagg gtaatagcgg aaaagaagta aaagctgcac
     2221 aaatcatgtt aactttactt ggttataatg taggtataga tagttctttt ggaagtaaga
     2281 catataatgc agttgtaagt ttccaaaaaa aatacggttt gtctgcagat ggaataattg
     2341 gtccagctac ttgggataaa ttgggtagac taactgaccc tactctttca taggattaaa
     2401 atctaaaaat atattaaata gtgtctcaat atgatttttc aatttaaatg agacactatt
     2461 taaatataaa tgttataaaa ctattttaca ataaattcca tataactcta ccatctatat
     2521 ccttaacatt ttgacaacca gtcaaaatca tagtctcaca taactcattc ctaaccttct
     2581 ctataaaaaa ctccacacca tcaagaccac cgccaaaaga agcagtaaca aaaggtcttc
     2641 ccatcaaaac agcatcagca cccaatccaa gcatcttaac tacatcaaca ccagtcctaa
     2701 ctccaccatc aacaagtatt gttatctttc cctttacaga cttagctata tctggaagta
     2761 cctcacaagt accaggagta taatcaagta ctcttccacc atgatttgaa acaataatgg
     2821 cactagcacc agactctaca gccatcaaag catcatctac agtcataatt ccttttataa
     2881 taaaaggtaa tctagtggat tcaaccaatt ctctaatctc atcaattgtt ttaggagaaa
     2941 aaggattttc ttgaaattga ttattaataa gtccacaagc atcaaggtct acaccaactg
     3001 caaaagcacc tgcttcttca gacaatctaa ttttatctat tatctttgaa ttattccaag
     3061 gctttataaa tacaattcca tttcccctat tatccttcaa tacatctaaa ttatccagta
     3121 aaaaagtatc tacattagta tcgccaacca tagcataaat tccagaatta gaacaacctc
     3181 taacaacagg ctctatgtat tctttttcgg aaactttacc acccatgttc aatatagtac
     3241 ctgatacagg tgcagcgaat ataggagaac tcatttttct accaaataat tctatggatg
     3301 tatctggctt tgaaacatta tgtatgactc tcatatttat ctttattttt tctagacttt
     3361 ttctattttc aatgaaagac gaaccacttc ctttaccacc cataccagga acatctccag
     3421 cacaagctaa tccattacaa attttacata ctttacatgt tccattaaag ttctctctag
     3481 ctgattttag taagtcattg taatccatac aaaatctctc ctttttataa tattaaaatt
     3541 gagtattact atattgaaaa tatcttaatt gtaaatatag ggatgttatt atgatgagct
     3601 aaactagata atacatatta gatatttttt attgttgtag atagttaaat tatatcatat
     3661 tagatagtca aattttgaaa aaaactaact tatttaagta tacattttga aaaaattaaa
     3721 aaagctatat atagattttt aaagaaatct atatatagct tttaagttta tgtcaatctt
     3781 ttttgttaat gaataaataa tatagaatac aatatacaaa aaagtttctt gaaatgctaa
     3841 gataatcccc atttacaaag caacatcatt atactgtgta aatttgaatc aacaatgttt
     3901 tcaccatatt tcatcataaa atcctctaat tgtgtgtcaa taaatgaata atatccactt
     3961 atactatcga tgtatgcagt cattaagtgt atacattcat cacttttatc tttatacata
     4021 tatatctccc cctatataca atatataaat ttagatacca aatcgtatca tattaaatag
     4081 ttaagtgtgt aacatctatg cagttatata tttatatcat tatattaata actaaagtga
     4141 gttttgacaa tagattttgg gaaactggat gttcaaagtg caaacttgga ttttaaaatc
     4201 attaattaag atagcgcata ggaatatatg tatacataac ttaattataa agattataaa
     4261 caattacttt tattaacttt atttaaatgg tagaataact tggagattaa taattataag
     4321 gaggatataa tatgagttta tataagttta tatatgatga taaggaatat ttattaaaag
     4381 aggagaactg tagtgcttta ataaatgatg aagaaaatcc agttcaagga gtaagtattt
     4441 caaaaataat tgatatactt aatgaagcag aagaagttga ttttgatgta gaatattatc
     4501 aagaagcatg tccattatgt ttagaaggag taaaagaaaa gaaaaaattc tttccttttt
     4561 tagaatatca cttttatatt ttcagtaaag atggagaata tgtaataagc aatatatctg
     4621 ttgattataa aggactatct tttaataaac tatcaagggc aaataaagtt gataatagtt
     4681 atattgtaag tgtgataatt tgcgaaaatt gtcaggatta tatagttcag atagaaaatt
     4741 gtatagttta gtgtaaagta tgtcttaatt taagagaaat ttctaaattg agacatcaac
     4801 ttttttcaaa aatagtatgg aaaattacta aatttatgag ataatgtaag tcggaggtga
     4861 gttacaatat atagtaaata tttggaagag atagatgata caattttaga ttcaatgttt
     4921 aaactaacct tgaatgaaag attattgact aataacgatt ttattgaaaa taaaattgat
     4981 gtagtaaaga atttaattga ttgctataaa actgaacaaa atagtttaat gttattaaaa
     5041 tcaaattttt tgctagcttt attatatggt attcaagggt ttagtgaaaa aatgaaagag
     5101 tatattttga tttcctgtaa atatattgat aaatgcttac ccaaagatta taaattttta
     5161 gcacgatttt attcacaaat agctatttta agtttaaaaa atgaagatgt aaataaggca
     5221 aatttatata tggataaatt taatcttatt tgtgatgaaa ataattttct aattgaagaa
     5281 attattttta aatcacaact tatttacatt aaggcaagta agtgtataga atcttctgta
     5341 ataattaaag agatagaaac gttgtatata aagataaaag aaattaacga ttttaattgt
     5401 aaaaaaatat atttttttat tattggtaaa atatattttt tgtttttgga tgatgctcta
     5461 attgctaagg taaatttttt aaaagcaaga aaatatgcag atttactaaa ggatatgcaa
     5521 gtatcttcac tatgtaatat aaagataggt gagtgtgaat gttcgtttga aaattatgaa
     5581 tgttccatgg aatatttcaa tgaagtaata agcaataaaa agtatagaaa tgtaaatata
     5641 attcaaaaat atagagcatc aaacaacata actaaaatat taataaagac tagaaattat
     5701 cctgtcgcaa taaataattt agcaaaatct gaagtatatc tagaaaaaat taaaaatcat
     5761 agcttaaaag aagtagagaa gtttgattta tttataagtt tagccatgta ttatgcaaaa
     5821 agtaatgaaa aatcttttga acaatcaata tgctatttag atagagctaa aaacatatta
     5881 aatatgataa aaaatataga agaatatata atatatgatt tagaaataat ttatcaccag
     5941 gcaaagatat attatatctt tggatattat gataatgcct taaacacaaa taaaaaactc
     6001 cttgaaaaat ctaaaaatgc taaaaattat aattatgtga agttagcata caagagtata
     6061 tatttgtgtt ttgaaaagat tcaaaattat gaaatgagta tgaaatactt taaaatgtat
     6121 tatgagttaa aaatgatgta tataaaagct cgaaatagaa attatataga ttccttaaat
     6181 tatagacatg agtatataga aaaagaaata aataacatga gaaaagtaaa acttgattta
     6241 gataaaaaaa agtatgttga ccatttgaca agtgcatata atagaacttt tttgaacgat
     6301 tttttagaaa aacaagaagt tagtgaatat tgcacagcat ttatgataga tgtagattac
     6361 tttaaagaat acaatgatac ttatggacac tataatggag atattgctct taaaaatata
     6421 actataataa taaaaaaata tctaaaaaaa gacatgctta tgataaggta tggtggagaa
     6481 gaatttctga tattatctgt atgtaaagat tataaaaaaa gtaaaatatt tggaagaaaa
     6541 ttatgtagga ttgtaaagaa atttttaaac aataatttga cagttagtat tggcattgat
     6601 acatgtaaaa atagtagtat agatataaaa gaaataattg aaaatgctga taaagcttta
     6661 tataaagcaa aggaaagtgg tagaaataga tgtttgcatt atcatgattt taagaatttt
     6721 taactgttga aataggattg gtgatttact tgaaaaggag tttaatagaa gatttaaaga
     6781 gaaatataaa caagatagaa tacgatatgt tgactaaatt ctatctaaat ttgacagatt
     6841 taaactacat cttggattat cacaaagacc ttttaaatac aaaattagaa gataatagta
     6901 gagtctatac tttatattta attagtctta taaactatat aaaaaaagat agagaagcat
     6961 catacaacta tttgatagag tcattaaagt atattaaaaa attgtcatta aaagatgatt
     7021 cagatataat atctaaaatt tatatttatc ttactttatc agctatttct ataagaaaat
     7081 atgataaggt aaataatttt tatttctcag caaaaaaaat tataagacaa aatcatttaa
     7141 atgagttgtt ggtattgtta aatatgagtt tatgtgtaga aataagtgct ttatatcaga
     7201 ccaaaacgga tgtaatagct ttagtagaag aagtgtcttt ttttaaaact ttaaaaaata
     7261 aagctcttgt aagtagggca aattatatat ttgggagagt ttatctatat ttatttaata
     7321 actttataaa aagtatggaa tacttaattg aatgtctaaa attggctcaa gaaaataatt
     7381 tatactctat agaggctttt tgtaaatgta taataagttt gtgttattta gagagtggaa
     7441 ataatgtaga agctataaaa tacataaata atgtattaga tgttgcacac agtaataact
     7501 caatatcagt aactgaaaga gtgtctataa aaatagacct tatatgggca tatttaaaag
     7561 aagatatgaa taaagaagca gaagttattt tattaaagac tataaaatta atgaaagttg
     7621 ttgaaggtgt atataaggat tatttatatt catttatatt tttatattca gctgaaattg
     7681 agttaaagaa agataattgt agttttgaaa aggtaaacac ctatttaatt ttatcaaaaa
     7741 atatatataa aagttttgga gatgttttta tatataattc taaactagat tacatatata
     7801 agttgtatgg agatttatat ataaaatttg gtaatataga tgaaggtata agttgttata
     7861 taaaaggttt aaatttagtt aaaaagagtt cattgaatct tagaaaaata tctatatttt
     7921 atgggctaat agcaaatgga tatgagctaa aaaaagattt taaactggca atagaatatt
     7981 ataaaagtat ggattggtat tctgataggt gggaaaaaaa taattcctat aaaacatctc
     8041 aagcaattca caaacaatat gaactcagac aaaaacaaga gagtttaaga ttactagtgg
     8101 atgataataa gaaattagaa aatgatattt taaaagatgg acttactaaa ctatataata
     8161 gaagatatct ggaacagcag ttggatttat ttaatgaaac cagagacaaa aatatggtcg
     8221 caatactggt cgatatagat tgttttaaaa gttataatga taattatggt catctagcag
     8281 gagataaagt tatagttaag gtaactgata ttataagaag tgtatttata gatattaccg
     8341 aacacataat cagatatggg ggagaagaaa ttttaatatt agtagattct atagaatcaa
     8401 tcggtgttga agagattgat aatatagaat tatatattaa aagagttttc aaacttcttg
     8461 aatttgaggg tattgaacat atatattcta aaataaaaaa ctatataact ataagtgctg
     8521 gagtaagtat aaaaagatgt cgtagtagaa aagatgttga aatattaatt gaagatgcag
     8581 ataagaacct atataaatca aaaaaagcag gtagaaatca atacattata atttaaaatt
     8641 gaggtgattt tgttgcgaaa aaaaatagga attatagcct ctgatattga attaaaagaa
     8701 agaatagaag aattatatag agaagatgta gaaaatggaa ctataataat cgacatactt
     8761 aacctagact taatggaaaa tcaaggtcgt atacttgttg aaaaaggtgc ccaagctata
     8821 attggtagag gtggaggtta tagtttagta atagatacag taaatgtacc tgttatacca
     8881 atgaatatga agtcaactga ccttttaaga gcaatagaaa tagcaaagaa atattctaaa
     8941 aaagtagtat tgattcttgg agacaatgaa gtttcttttg actatgttgg ctggagaaat
     9001 gtcataagta ctgaaataac tgaagaatgg tttgaatcta agtatgagat aagaagtaaa
     9061 gttgtaaaat atatagacca aaaagatgaa attgtaatcg taggaggagg tttggcatgt
     9121 tcttttgcaa ggcaatatgg aattgatagt gtatttgcaa ctgctagtga tgaatctata
     9181 agagaagctg tagaatattg taaaaaatta ttagatacat taggtgaaga aaagtttaat
     9241 aatgaagtgt tacgaaatat acttgatggt ataaaagatg gagtaattgc tatagatagt
     9301 aatggcagta taattttgta caatgaaagt gcaaaaaaca tgcttaaagt agagagaaaa
     9361 tgtgcactta ataaatacat cttagatgta tttcctaaaa tggagtggat gttagattgt
     9421 ttacatgaaa aagaggacgt agaagataga aagataagaa atataaataa tctaattgtt
     9481 aatactagga caacattgat aaaagttgat aatagtactt atggagtttt aggaataata
     9541 caagatataa ccaagctaca aaacttagaa agaaaaataa gatttgactt gaatcaaaaa
     9601 ggtctctatg ctagatatac ttttgatgat tttttattta aagataaatt aactaaagaa
     9661 tttattgaag aagctaaaaa aattggaaaa agtgattata caactttact ttatggggaa
     9721 agtgggtctg gtaaagaaat tatagctcat agtatacaca atataagtaa aagaaaagat
     9781 aggccttttg ttgctataaa ttgtgctact atagcagaaa atttacttga aagtgaactt
     9841 tttggctatg aagaaggtgc atttactggt gctagaaagg gtggaaaaag agggctattt
     9901 gaacttgctc atggagggac tcttttttta gatgaaataa atagtctatc ctttaatatt
     9961 cagacaaaac tattaagagt aatagaggaa cgtcaaataa tgagaattgg ttctgattat
    10021 ataatacctc tggatataag gattatagca gcaacgaacg aatctttaac cgaaaaaata
    10081 gttatgggta catttagagc agacttattt tatagattga gtagtttaga gataaatata
    10141 cctcctttaa gagacagaag agaagatata atacctttgt ttaacaattt tgtaaatgaa
    10201 gtattaaagg atgatggtct caatggaata aacagtatag atgaaaattt tgttttgact
    10261 aaagatgaaa tggataagct atataattat agctggcctg gaaatgtaag agagttaaag
    10321 acaatagctc aaaaatatgt tgtgacaggt aaaattaaat tgagacaaga tagagatttt
    10381 aaaactaaaa aattacttcc taactctgaa gtagacaaat ttaattctga aacgacagca
    10441 agtgtagaag tccaagatga atctataaat ataagtaaga taaatgatgg taagataagt
    10501 atagatataa aagaagtaaa taagtatgtt gaagaaaaaa taataagtat gctttttgct
    10561 caaggacttt ctaaaaatga agttgcacaa gttcttggaa taagcaggac atctttatgg
    10621 aagaaataca ataaaaatat ttaaatataa ttacatataa attattttga agtaatgtta
    10681 attttttaaa acaagtgtta agaaaaatta acattacttt tttgcaaatt tttatttttt
    10741 tagacaggca tatatattta taagaaaaat agttaaaaca cttaatttaa taatgaaaaa
    10801 aataataatt ctaaacaaaa tcaattttac ataaagtggg atttattggc atagtaattg
    10861 cttaatatat aatgtaagag taaatacaat tttaggggtg atggtatgag tcaaagtatg
    10921 gttggtaagc atgcaatgtg gccaaaagaa aatgatgtta tatttagcat atctggcaga
    10981 gctcaagcag cagagaaggc ttttggtatg gataatgtaa taaatgcaac aataggcgct
    11041 ctaatggatg attcaggaaa attgataaca atgaaaactg tatatgaaga atataaagca
    11101 ttagataact gtgagatagg tgcatatgca gctcttgaag gtcaaccaga ttacttagaa
    11161 gcagttaaaa aagtattttt cagagattac ttaccagaag gacatataag agtattagct
    11221 tcaccaggag gaagtggtgc aataaaatta gctgtatgga actatactaa tgaaggagat
    11281 gaggtattaa catctgattg gttctggagt ccatatgtaa gtatagctga agaggctaat
    11341 agaaaagtag ttaattacca actttttgat gaaaatagaa ggtttaattt tgagtcgttt
    11401 aaagaaaaat ttgtaaatat agcagaaaaa caaggtagag tctttacaat tataaacaca
    11461 ccagcgcata atccaactgg atatagtgtt gcagatgatg agtgggataa aatattagac
    11521 ttatcaaaag aagtcgcaaa agataaagac aaaaagataa tatttttcgt agattcagca
    11581 tatattgact ttgcaggtga tgatgatgta tgtagaaagt tttttaagaa attttctaat
    11641 ttgcctgaaa acgttctcgt attggttgga ttcagtatgt caaaaggatt tacagcttat
    11701 ggtatgagaa tgggggctat aatttgtata tcttcaagtg aagatgtagc tgaagagttc
    11761 cattactcat gtgttcattc atgtagagca aattggtcaa attgtaatag aagtgccatg
    11821 gcagtattat ctaacattgt aaatgaccct aaaaaattca aagaatatga ggatgaaaaa
    11881 gaaatataca aaaacatgct tactagaaga gcagatgtat ttgtaaaaga agctgaaaga
    11941 gtaggattag aaattcttcc atatatagca ggtttctttg taagtatacc atgtgataat
    12001 ccaaaagaag tatgtgaaga attgactaaa cataatttat ttgcagttcc attaaaaatg
    12061 ggtttaagat ttgcagtttg tgcagtttct gaagataaat gtaagaaagc accaagtatt
    12121 ataaaagaag cacttgaaag tttagaagta aaaataaata attaatttca ttgaacaaat
    12181 tgggtggact atgaatttaa taattgtaga tggagggaat tttatatgaa acaattgatg
    12241 acaggtaatg aagcaattgc acgtggagcc tatgaggctg gtgttaaata tgcatctgca
    12301 tatccaggga ctccaagtac agaaatatta gaaaatatag caacatataa agatgcaata
    12361 gttgcagagt gggctccaaa cgaaaaggta gcacttgagg ctgctatagg gggttcaatt
    12421 gcaggagcaa gaacaatggc ttctatgaaa catgttggtt tgaatgttgc agctgatcca
    12481 atatttactt atgcatatac aggggtaaat ggtggtatgg tacttattac agcagatgag
    12541 ccgggaatgc attcatctca aaatgagcaa gacaatagga tgtatgcaaa atttgcaaag
    12601 atacctttat ttgagccatc aactagtcaa gaagctaaag atatgataaa agaagctttt
    12661 gaagttagtg aaaaatacga tacaccagtt ttatatagag ttacaacaag actttgtcat
    12721 tcaaaaggat tagtggagtg ctatgataga gaagaagttg aaattaaaga gtatgttaaa
    12781 aatgctaaga aaatggtaac tgttccagca aatgctcaaa taagaagggg cgttgttgaa
    12841 gaaagaatgg aaattcttaa aaaattctca aatgaaactg atttaaacta ctatgaaata
    12901 aatgatacaa aaataggtgt tatagcctct ggtatgtgct gtaattttgc caaagaagtt
    12961 tttggaaaaa atgcatcata tatgaaacta ggatttacaa atccattacc ttatgaaaaa
    13021 ataaaagaat ttgcagaaaa agttgataaa atatatgtta tagaagaaaa tgacccattt
    13081 atagaagaac aaataaaagc atatggaata gattgtattg gaaaagatgt aataccacca
    13141 tatggagaaa tgacaccaga tgttttaaga aaagctatat ttggaaaaac aaatgatact
    13201 atagaataca aatctgaatt agtaacacca agaccaccaa gtttctgtgc aggatgtcca
    13261 catagaggat tcttctatga acttggaaag agaaaaaatt taatagttgg tggagatata
    13321 ggttgttata ctcttggatt tgctcctcca tataatggaa tagattatgt tgtttgtatg
    13381 ggttctgctt ttggaactgc acatggagct caaaaagttc ttaatatgaa ggatgataat
    13441 gaaaaaagat tggtaggtgt acttggagac tcaacattct tccatacagg aataaatgga
    13501 cttttagatg ttgtttacaa tagaggtaat tctatttcgg ttatattaga taatagaata
    13561 actggaatga caggtcacca agaaaaccca ggttcaggat atactttaca aggtgctaaa
    13621 actaaagaag ttgatataga aggattagtt aaagcttgtg gaatagaaca tgtaagagtt
    13681 ataaacccta ataatttaaa agaagtaaat gaagcactag attgggcttt agctatagaa
    13741 gatgaaccat cagtaataat aacaagatgg ccatgtgtac ttaaaaaatt ctctaaagaa
    13801 gatatagaag aatttaataa tccatttaag actaagtgta aagttgacca tgataaatgt
    13861 ataggatgta aattatgttt gaaaactgga tgtccagctc tatcatttga taaagagaat
    13921 aagttatcaa atatagatag aaatcagtgt gtaggatgtg gagtatgtgc acaagtttgt
    13981 ccaaaacaag caatagttaa ggaggaaaaa taatatgact aagagtatac ttttggtagg
    14041 tgtaggaggt caaggaacta tacttgctag taaattatta actatgggat tgatggaagc
    14101 tggatatgat gtaaagatga gtgaaataca tggaatgagt caaagaggag gttcagtttc
    14161 ctcacaagtt agatatggag attgtgttca ttctccagtt atagaaattg gtggagcaga
    14221 tatattagta tcttttgaaa aaatggaagc tttaagatgg ttcaattatt taaaaccaga
    14281 aggaaaagct ttagtaaata atcataggat agattctatg actgttttaa tcggaggagc
    14341 tgaatatcaa gaaagtgata tagatgcaga gttaagtaga ttaaatgcaa aagttataaa
    14401 tgcagctgat aaagctgaag aactaggaaa ttcaaaaata atgaatgtta ttttattagg
    14461 atgtctagtt aaatctatgc aattagagtc tattgattgg gaaaaaatta taagtgaaaa
    14521 tgttaaacca aaatttgttg aattaaacat aaaagctttc catgaaggta tggaaatggt
    14581 tagcaaatag tttataatag atataaatag actatagaaa ttaaggtgaa aggaagaaaa
    14641 ttatgactta cagaatatta gccataaatc caggttctac ttctacaaaa atagcagtat
    14701 atgatggaga agaacaaatt cttgtgaaga cgatagacca tccagctgaa gagattgcaa
    14761 aatataatac tatacaagac cagtttgaaa tgcgtaagga agcagttttg aatattctta
    14821 aagaaaatag tatagactta aaatctctta gtgcaatagt aggaagaggt ggagttttac
    14881 caccagtaaa atcaggagca tatttagtaa atgaagaaat gattgatgta ctaagacata
    14941 gaccagtact tgaacacgct tccaatttag gtgctgttgt ggcacatgca atatcagaac
    15001 ctcttggaat caactcatat atttatgatt ctgttgcagt agatgagctt atagatgtag
    15061 cgagaatatc tggactttgt ggaatggata gatcaagtgc agggcatgca ttaaatacta
    15121 gagcaatggc tttaaaatat gctaaggata aaggaaaaga ttataagagc ttaaacttaa
    15181 tagtagctca cattggtgga ggagtaagta tttatcttca tgaaaaagga agaatggttg
    15241 atatgctatc tgatgatgaa ggaccatttt ctccagaaag gtcaggaaga gtacctgcta
    15301 caaaattagt ggctgcctgt tattcaggtc aatattcaga aagagaaatg actaaaaaga
    15361 taagaggtaa aggtggtata gtttcatacc taaatactgt agatgctaga gaagttgaaa
    15421 aaatgatagc agaaggaaat gaagaagcaa aaattattta tgaagcaatg gcttatcagt
    15481 tagcaaaagg tattggagag ttagcaactg tagtagatgg aaaggtagat gctataatta
    15541 taacaggtgg aattgcatat tctgaaatgt ttacttcaat ggttaaaaag aaagttgagt
    15601 ttatagcacc agtagaaatt atggcaggag aaaatgagtt ggaatcactt gcttttggaa
    15661 ctttaagagt actaaatgga gaagaagaag ctagaattta tagtgaaaat taataagaaa
    15721 aactaaaaat gtttatatac taaaaaagtg gtatatccgt tttttataca cgaaagctta
    15781 gagtataggt gaaaatgtat aaaatttgga ttgccacttt ttataattaa aattttatct
    15841 taacctaata aataattctg taaaatttcg tatttatata tatattttat tggtatttat
    15901 tgttattatt attatgagga gtgatttttg atgggaaaaa taagtttaaa aagtatgata
    15961 agattatttt caggtttttt tatatttgca atttcttctg tgcttatgat taatgcacat
    16021 gtaggtctta tgccttggga tgtacttcac caaggtttat ctataaagct aggcataact
    16081 ataggtcagg cttctataat ggtaggagtt gtaattgtta tattggatgc agtttttggt
    16141 gaaaatatag gatggggtac tttactcaac atgacattta taggaatttt tattgattta
    16201 gtaatatttt ctggagtgat acctcatgca agcaacactt atataggtgt gtttatggtt
    16261 gttataggaa ttattttggc agctatagca agttttctat acttaggtgt ttgtttagga
    16321 agtggaccga gagatgggct tatgattgct cttcagaaaa aaactaataa atctgtacgt
    16381 cttgttagaa caattcttga aatactagca ttagttgttg gatggttatt aggaggttct
    16441 gtaggtattg gtacgcttgt aagtgcttta ggtttaggat atgtattaca aatagtgttt
    16501 agaatattta aatttgacac aaaattgctg aaacatagat ttattataga tgatataaga
    16561 gaatggaagg aaaagaaaag caatgaacat aaatgtaaat caagtattgt aataaaaaat
    16621 gagcagaatt aattatgcta aaatatattt gtagtttatc taatttatag taaagtcaag
    16681 gagattttga aatggaatta tgggatttat ataatgctga tggaattaaa acaggaaatg
    16741 ttataaaaag aggtaattct attgaagaag gttattacca tttggcagtt gaagtgtgga
    16801 ttttaaatag taactctcaa attttaattc agaaaaggtc taaaagtaaa aaaacattgc
    16861 caaatatgtg gggaatgaca actggatgta ttgtttctgg ggaagacagt ttagaaggag
    16921 caattcgcga agcaaaggaa gaaataggga tagatataac taaagatgag atgaaagttt
    16981 ttagaagtat gattcatgaa gatactcttt gggatgtata cttagttaaa aaagaatatg
    17041 atatatctaa agctatttta caggaggaag aagtaagtga tataaagtgg gtaagcacag
    17101 atgaaataag acaattacta aaagagggtt tgttttttga atatccagag atatacgaat
    17161 tgctatatga gatagataat aataaattaa atatatgatg tagagcagat ttcagtataa
    17221 gtaagattat ttaaaatgta tcttctctaa attttaatat tgttttatga aaattaataa
    17281 gttattttta gtatttttct acttgttttt tgagattaaa ataaaaaggg cagtcattat
    17341 aaagtcataa aaatttgggg aggatttaaa ctatggaaga taacaaagga ttggcacgtg
    17401 acagttcaaa atataaaatt gtttctatat ctgtcgtagt aattattcta attacatttt
    17461 ggtatatgtt aaatatggtg cttttaacat ttattatgac ttttattttc tataacttgc
    17521 ttgtagccac aagaaaacga attaagaagt tttcttcttt aaatattcca gattcattga
    17581 taattatagt gttatatgca ctatttgcta tattgttagt attgattagc tatgcagttg
    17641 taccaataat tatagttcaa cttacagagt tgagtagggt ttttagtgat tttgatgtaa
    17701 atcaatttgc tcaatcttta ggaccgaaat tgtatcctat tgtctcaaag ctggatttta
    17761 ataaatatat ttcacaagca gggctactta tagcatcaac agcaacaaaa gttggaagtt
    17821 ttggagtaaa tatattattg gcatttttac tgagtttact ccttttactt gaaaaaaatg
    17881 aaattaaaaa ttttggagat aaactttctg atagtaagat ttcttttatt tataattcgc
    17941 ttgtattttt tggaaagagc tttgttaaaa attttggtga agtaatgaaa gtacaagtta
    18001 tgattgcctt tataaattct gttgtttcta tgattttctt aggtttcatg ggattccctc
    18061 aaatatgggc tttaggattt atgatttttg tgttgggtct tattccagta gcaggagtta
    18121 tagtgtcttt gattccatta actgtaatag catttaatac aggaggaata acaaaggttt
    18181 ttggagtttt acttatgatt tgtatagtgc atgcagtaga aacatacata ttaaacccta
    18241 agttgatgtc gaatagaact aaacttccag tttgttttgt ttttattatt ttacttgtag
    18301 gagagcatta tttaggtgta tggggattac taattggagt tccaatattt atgttcctta
    18361 tggatattct gggtgttaaa tttacttcta ggtaatatat taaaataata atttattttt
    18421 atatataaat tatgaattgt tttaaaaaag aacctataaa tagacatcat taataaagac
    18481 atctatttga taggttcaat tttgctttgt ataaatacta taaaactaaa taaaaagaaa
    18541 tttatttcat ttcaaaagtt tcacaacttg catttctttc atttatatga actttttcag
    18601 ctttgcaaag ttcattttta ttgtatttac attttacagc ttcacaatga atgttatctg
    18661 tatcaacttg gttagtttca ttagaacgac tagttatacc agatgtatat ttgtcttcaa
    18721 aagaagcaca ataagtattt tctgtagtag ttgcttgcat tccatctact tttatactac
    18781 cagcataaca atatccacta gtattataag cacaattagt agcagcacaa tttaaattat
    18841 tatttttcat aaataacctc ctaagtttta tttaaactta ttatgtgaag ttatctaaat
    18901 tttatacact tatttacaat tacatttatc acatttaaca actacatctt tggaagtttc
    18961 ccttcctaaa tttttattaa catgatacac atcaacattt tcagttgatc cacatataga
    19021 acatttaaaa ttgttttcta gtagggttct ttctttaaat aacttccaat acatagaatt
    19081 gatgtaatca ttataattta ccttgaggca tgtctcaaga aagtttatgt atagattgtc
    19141 taaatctcct gtatttaatt ctgtatattc tggttcaaaa tattcacaac atcctctaaa
    19201 atcgggcttt gtatctgaaa taacacatct aatatcatat ctatagtcta ggctaggccc
    19261 cttaaatgaa agatgtgtgc aaaaagaaca agatatttct ggtagatttt tttcaagttc
    19321 atgtaattta ttattcataa gtattcctcc aaaaaattta ttttaagtat ataaatgaat
    19381 agattatttt aaaactttta tttatttata ttagagattt aggataaata ttccaataag
    19441 gagtaaatac ttaagtattt attactgtat taaataaaaa agaggcaaat ctaacttgag
    19501 attgcctact tttttatcat tttttaataa aatttattct aagtattatt ttatttagat
    19561 ttagtcagcc aacttagtat ctgctttgct ttttaacttt ctaccagagc gtacagttaa
    19621 aatagcatat aatacagtaa atatggcagc taaaacatat gatatattta tgtttaagtt
    19681 aaatccaatt tgagcattaa atatataact gaatataaca aaggaataaa acataccagg
    19741 aattaagctt ataatataat tcttttcttt tattataagg taaactgtaa tcattgcaaa
    19801 tgcaaatatg gcaatagttt gattactcca agagaagtat ctccacaata tattaaatcc
    19861 agaagcacta agctttgcaa atataaggat ggctatgaca ggaataaata tacagattga
    19921 caatataaca cgatgtttct tttccttttg gtcataatga aagtaatctg caagcattaa
    19981 tcttaaagat cttaaagctg tatctccaga agttattggt aaaacaatta cacctattat
    20041 agctatgata ccaccaatag aaccaagtaa atctcttgca accaaaccta ttacatcagg
    20101 agaacctact aattctttag gtattccttt attgtaaata cccatagcag ctgcagccca
    20161 aatcattgca attaaacctt ctaaaatcat catattataa aaagtagttt ttccttcttt
    20221 ttcatttgaa actgatcttg ctataagagt agcttgagtt gagtggaatc cagaaacaat
    20281 accacaagca actgtaacaa agaatgtagg aataagagga ataccatcag gatgaatacc
    20341 tttccaattt gcaagactta aattagctaa atcataacct tgtgtaaaga ttccaattcc
    20401 aacaccagca gcagataaaa gtagaatagc tccaaatatt ggatatacct ttcctatgat
    20461 tttatcaatt ggaaatagtg ttgcacacaa gtaatataga aagataagtc cataaactat
    20521 ccagacaact ggattattta tagtcgattt catatttaaa atttgagtaa caactaaatc
    20581 cccaggtgta taaataaaaa ctgcaccaac taaaagcatt aaaagacaaa ggaatatatt
    20641 atagacttga aatactttat tacctaaaaa tctactgata agagaaggca tttgtgctcc
    20701 tttttctctt atactaatca ttccactcat atagtcatgc aaagctcctc caaatacaca
    20761 gccgataggt attagtatga atgctattgg accaaacaat ataccttgga taggtcctag
    20821 aattggtcct gtaccagcta tattaagcaa ctcaattaga ctatttttcc attttttcat
    20881 tgggacatag tctactccat cactttgagc aagtgcaggt gtttttctgt catctgggcc
    20941 aaatactttt tcacaataag caccatataa agcacctcct attagtaata tagccaagcc
    21001 gattaagaat gttgtcataa tatcacccca tttataaaat tttttggtct ttgtatacat
    21061 attatctaaa tgtgtagatt tatattgaat ttaattctgg acaacctaca aattctataa
    21121 agtattacaa ctaatataat ttcagaaata aatacatata cataaccatg tacttagtat
    21181 acaggtattt ggtaatattt tcaatgttat agcaataaag aatataaaca aaattctgat
    21241 aatattttac aaaaaaatta aaaaatataa aaattagttt aaatagatgg agaaaaaagg
    21301 aaaatcaatt gagaatataa atgtctatat cttaacaata ttaagaggtt taaaattctt
    21361 gaagaaagaa tagtcaagtg atataatggg tttacaggtg tatatacact agtacatata
    21421 gaaagcggtg caattatgga taaagattta acatatcaaa tcaaagagct aaagaaagaa
    21481 aaaaatgcaa taatacttgc ccatttttat caaccaccag aaatacaaga attagcagat
    21541 gcagttggtg actcatatta tttaagtgag attgctagag attgtaaaga agaagtggtt
    21601 gtattttgtg gagtaaggtt tatgggagaa agtgctaaga tattatcacc tgaaaaaact
    21661 gtattgatgc cagtaagtaa cgctgggtgt gctatggcag atatggtaga tgaagaaggc
    21721 gtgataaaat taaagcaaca gtatccaaat gctttggttg tatgttatat aaactctaca
    21781 gctaaagtta aggcacattg tgatgtttct gttacatctt ctagtgcaat taaaatacta
    21841 gaaaacatag ataataaaga aattatattc cttccagata aaaatttagg aggatatatt
    21901 gcagaacaat ttccagataa aaactttata ttttgggacg gatattgtaa ataccataac
    21961 aatataagag ctgaagaaat aattgagtta aaagataagt ataaaaatgc agaagtatta
    22021 gtacatccag aatgtaaaaa agaaataaga gatttaggag attatgtagg tagtacatca
    22081 ggaataataa aatatgctac taatagtaaa aacaaagact ttataatagc aactgaagaa
    22141 ggtatattac atgaattaaa gaaaaataat cctaataaaa acttttatat tcctggtgga
    22201 aaaatactat gtacagatat gaaaaagaca acattagaaa atttatatag tacacttaaa
    22261 aatatggaaa atgaagttat tgtagaagat gaaatcatgg aaaaggcttt aaattcactg
    22321 cttaacatgc acaaattagc agaaggatag agggatagac ttatgaattt agaacaagat
    22381 gttttaatag ttggaagtgg agtttcagga ttatactgtg cattaaattt agataaaagt
    22441 ttaaatgtgc tagtagtatc gaaatcaaca attgaaaaca acaatacata tcttgcacaa
    22501 ggtggaattt caactgctag aaatattgat gatatagaat cctttgtaga agatacaatg
    22561 aaggctgggc agtataaaaa tagagttgaa gcagttcaag tacttgcaga tgaatctata
    22621 gaaaatgtag gtcagatagt agaatatggt atgcctttag acaaagaaaa tggagagata
    22681 gattacacaa gagaaggagc acatagtgta aatcgaatag ttcatagtaa ggataatact
    22741 ggagaagttg tttttaaaac tttattaaaa gaagctaaaa ctagagaaaa tataactctt
    22801 atagaagatg catatctttt agatatatta aaagatggca ataaatgtat aggagctaga
    22861 atttttaaat ctaaaaaaga gattcatgtt ttttcaaaaa tagtagtttt agctacaggt
    22921 ggaattggtg ggctttttaa aaattctact aatcaaagac atcttacagg tgatggaatt
    22981 gcaatagctt taagaaataa tataaaaata gaaaatttag aatatattca aatacatcct
    23041 acagcctttt atgaagaaaa taatgaaggt aggagaatgc ttatatctga atcattaaga
    23101 ggagagggag ctaaactttt aaataaaaat aaagaaagat ttgtggatga acttcttcct
    23161 agagatgtag tttcaaaagc tatttttgag caaatggaaa aagataaatt accttatgtg
    23221 tatttagatg caacacattt agatagtgaa tatttaatta atagattttc ttttatttat
    23281 aatgaatgtt tagctagagg aacagacata acgaaagaat gtataaaggt atctcctgca
    23341 caacattatt ttatgggcgg gatacatgta gatttggatt caaaaacatc tatggaaaat
    23401 ttatatgcag ttggtgaaat tagttgtaca ggtgttcatg gagccaatag attggcaagt
    23461 aattcattac ttgaagggct tgtattttca aaaagagcag ctaaaaatat aaactcagtt
    23521 atagataatg taaaagttaa gtttatagat gtaccagata tggatataga tatagaacag
    23581 gtaaaaaaag aaaataaaat attagtcata aaagaaattg aaagaacaag tgaggatttt
    23641 ggcgatgaat tatttgatta ttgatagaat gatacaggat gctttgatag aagatgttcc
    23701 aagtgaagat ataacaacta attctattgt ggatgaaaat tctaaatcta ctgtagattt
    23761 aatttgcaaa caagatggta taatagctgg cttaggtgta tttaagagag tttttgagat
    23821 acttggtgat gtagatgtaa aattatataa aaatgatggt gatagagtaa agaatcgtga
    23881 aaagatagct gtattaacag gtagtactag aaacttactt gtaggagagc gtgtagcatt
    23941 gaattattta cagagaatga gtggtatagc tactattaca agtaggtatg ttgaaaagct
    24001 tgaaggtaca aatacaaaat tattagatag tagaaaaacg atacctaatc ttagaatatt
    24061 agataagtat tctgtcaaag taggtggagg atgcaatcat agatttaatt tatctgatgg
    24121 aatattgctt aaagacaacc atattggggc tgctggtagt gttaagaagg cagttgaatt
    24181 agctagaaaa aatacttctt ttgttagaaa gatagaagtg gaagtggaaa ctttagacat
    24241 ggtaaaagaa gcaatagaag ccaatgcaga tataataatg ttggataata tgagtttgga
    24301 aatggcaaaa caagcagtag atattataaa tggaagagcc attgtagaat tttccggaaa
    24361 tgtaaattta gatactatag aagatatagg aaaaattggt gtggatgttg tttctgtagg
    24421 agcgcttaca cattctgtta aagctctcga tataagtatg aagaatttga gaaatatata
    24481 aattttatat tgaaataaac ttaattaaaa tagactcctt aaatttgttt tataaattta
    24541 aggagtctat tttttattca ttaaaattaa taaaaataga aaaaaatcaa tcaataattt
    24601 aataaaaata gataaatact atatacactt ttaataatat agttaatatc tattttacag
    24661 ataaataaga ataaacttat aatataattg tatctgtaaa attttgtaaa atataaaaag
    24721 tataggggga ataaaaatga aagtagctta tatttttagt agtactaata cacataaaat
    24781 tctagacaaa atgataatac cacaacttga acaaggaact catggagtag acgttctagg
    24841 gatgtttttc tttatggata ataccttatt tttatctaaa ggtaatcctg taggcgagag
    24901 actaagtaaa ttacatgaaa aaactgatat gataataatg gcttgtgacc aatgtgctat
    24961 agaaagaggt atagagaata atttggttga tggagctaca attggatgtt tcccaaacct
    25021 atatgcttgt ttaggcagtg caggtgtgga ccaagttata acgttataaa ttagtatagg
    25081 atacaatcca tagaaaaatt tattttctgt ggattatttt aagtaaaaga taaattgttt
    25141 aaagtagggg atgaacaaat gtctaaaatt ttagttgaat ttataaacac ttgaccatct
    25201 tgtgatgaac atggagtgtt tataaaaaaa atgtcagaaa agtatgctga taaattggaa
    25261 ataaaattat atcaagcagg gaaagatttt tcgtatataa aaaaatatgg gattataaca
    25321 aaaggaactt taataataaa tcagaaaaag aaatatgata gattaaataa agatacaatt
    25381 gaaagggcaa tagtagaagc tataaacaat aattaaaagt ttaaaaatta ggagtatcaa
    25441 aaatgaatat attagaaatt gttttaaatg gagttaaaga tactatagta gcttctatag
    25501 ttacactgaa tggagcatca ggatggctta tgataagttt tatcttggca ggtgtacttc
    25561 acaatgtttt aactccaaga aggtttcaaa aacaacttgg aaataagaaa ttttcttctt
    25621 taattaaaag tactatctca ggaatgtttt taccaatatg tagttgtgga gtaataccac
    25681 ttggaataag tatgtattat tcaggagcat atttaggacc agtacttgct tttatgacat
    25741 caactccaat aataaatcca atagctgtag ttctttgtct aggtctttta ggtcctaaag
    25801 ttacaatcat ttatctaata gctggttttt tagtaccatt tttagtagga tttttaggaa
    25861 attgttttgg aaaagaagaa ttatcacttc ataatgattc agaggaagaa gtaatagaat
    25921 tagaagaaga aaaaagaagt tttatggaaa atatgattga tggtcttaaa tggtcttttg
    25981 gtgaattagc ccttactatt agtaaatatg tagtaatggg tatggttttt gcaggattta
    26041 taacaactat ttttccaaat agtataattc aaaaatattt aggaaatcca ggtttgctat
    26101 ctcttggaag tatagcaata cttgcatgtg ttatgtatgt atgtgctgta ggacatatac
    26161 cgtttatagc agcccttgtt gcaagtggag catctcctgg tatagcgata acatttctaa
    26221 tagctggagc agctacaaat ctaccagaac ttataagtat gtttaaactt attggaaaaa
    26281 gaactgttat tatatattct gtaactttga cactgtcttc aataataatt ggatatataa
    26341 caaatttact tttagtgaat aataactcag taaatttaga tgcaacaaat tcttcaatac
    26401 agttggcaaa taaactaatg ttaaatatac ctgatagttt tgagtatgta tgtactattt
    26461 taattatttt atttgcattt aaatcaataa taccaaagat gaaagaggtc ataggaaatc
    26521 atgcttaaaa agatagttat aatatcctgc atagtagttg tgttaatcat tttatcaaaa
    26581 atagttgatg ataacatcaa agaagatgct tctattccaa atgtgaataa agaaacatta
    26641 gaatatttta gaaaaaatta taaagaagac ataataactt gtgctgaaga agacttaaat
    26701 aatgatggga aaaaagattt agtagttata tataaaaaaa gcaataattc aaatgaaatg
    26761 gtagtcgtag tttctgataa aaatagccac tatataacaa agccaatacc agcacctata
    26821 gagaatcaaa ctataacctt taaaaatatt gatgataaag caccaataga agtaattgta
    26881 tcagggtcta aaaatggtaa tgtaggatat gctatttaca gagtagaggg taaaaaattt
    26941 gttgatttat ttggcgaaga tatggacaaa tgttgctaaa aataaaaata atacataaag
    27001 gtgggaaatt tatatgaaat tatctaagaa gattcaagca ttaatcttat ttggtgtaat
    27061 gggtacatct atattaacag gatgtagtag taaaccaaaa gaaaaagaag aagcaaaaac
    27121 tggaaaagat gattatacaa taacagtagg ttattataat tgtgaccata tgactgcggg
    27181 accagtagca gaatcggcag gaatatataa agatttaggt cttaatgtaa aaactgttgg
    27241 aaatggtaaa gttcctgaag ctatggcagc aggaaaaatg gatgcaggtt acataggaac
    27301 taaggggtta gttggagcaa tacctaaggg ttcaccaata acaatagcag ctaacaacca
    27361 tactggtggt tctgaatatt taatagtttc aaaagatata aaagaaccta aagatttaat
    27421 aggtaaaaaa attgcaacag atatgagtga tttcttatgg acaagtgatt atggtccaga
    27481 aacaggtcta ccaactgacc catcaaaata tgaagttgta aatatggatt cagacaaaga
    27541 taaatattta gctcttaaaa ctgggaaaat tcaagctttt acatcttgtg acccttgggg
    27601 ttctgtagct gaaaatgacg gtgcaggaaa aataatagca tctactcaat ataaagaaaa
    27661 agctaatggc aaagaatata actgttgttc attctcatta aacaaaaact ttataaaaga
    27721 acatccagat ttagcaaaaa aattggttct agcacataca aaagcaatag aatatatata
    27781 tacaaatcca gctgaagcag ctaaaatatt tgcaaaatat tataatgtag aagaagaagt
    27841 tgcacttaga actatctata agaagactgt tggagaaggt agaactctta cttggaaagt
    27901 tacaggtgaa gaatataaaa ataatttaca aatgtataaa gatttaaagg ctttagatga
    27961 tatacctaaa tatgaagata cgattgatac aagcttattg gactcttgtg gagctgatga
    28021 ttttgacaaa tttataaaag aaaaagttaa cccagagttt cctgaaggta tgagttatga
    28081 agactggaaa gcaaaggtat tataaataaa tggagaatat gaaaaatata ataatacttt
    28141 ttatcattat tttgggaagt atatttataa tattttttaa ttttgaagat aaagaagaaa
    28201 taaaaggaaa attaagaata ggggtatctg atgatacctc tggttttgta ataaattata
    28261 tggtaaatag agactacttt gaaaatataa aagtaagtga tataatggat atttttacaa
    28321 ttaatgattg ctgagcaagt acaatgcagt gggctctgag ttcagaggaa atagatatag
    28381 caatcatatg taaagatgct gcaaaacaat atgtaaatgt aaatagtgga tttgaaattg
    28441 ttggtactgt agttcaaaat tctgatatat ttctattaag tgataataat cctgaaaaga
    28501 taggagtcat tcaaaataga gattaccagt cagaattggt taaaaaatac tacaagaatg
    28561 tggaagtagc tcccttatta gggactgcac tagcatatgg attagaaagt aatttagtag
    28621 atggtgttgt aatagattgc ataaagtcaa ttgggttaga gggcaaaaga aaatctacaa
    28681 ctaaattagg agattatgat acctatgtat tagttgtaag taaagagttt aaaaaaagta
    28741 aagcatatag tgattttata acactttaca ataaaagtgt tgatgcttta aagaataaag
    28801 ctacatttaa gaaagcatta aaagagtaca ggaatataag aaatatagat atggaggaaa
    28861 taagcaattg gaaattaaaa tttctaaaga taaaagcgat agattaacta agaaaaaaac
    28921 tgatggtagt atggatattt tatataaaat aatactatta gttattatat ttttagtctg
    28981 gcattttgca gcaaaagata tagggagttc tttgttactt ccaatgccag tagatgtaat
    29041 aaaaggtttc tttttctgtg tgacagatgc agagacagtc actaatcttt ttataacatt
    29101 gcagagagta cttaaaggtt ttatgtatgc attattgttt gggcttccaa taggatttat
    29161 tatgggattt tctaaaactt ttgaaagggt tttatctcca gtagtagatt ctgtaaggca
    29221 agttccaata atggcatggg ttcctcttac tatagtatgg tttggtatag gagatggtcc
    29281 aacaatattt ttaatagctt tttcaggggt tttccctata attttaaata ctattcaagg
    29341 agtaagagca atatcaaagg attattataa tgcagctaga agtatgggag catcgccaat
    29401 tgtgatattt acaaatgtaa ttgttcccgc atctcttcca gatatactaa ctggttcaag
    29461 gattgctata agtacaggat ggatgtctgt tatctgagcc gagtttatag ctacgagtgc
    29521 cggtctcggt tactcaatgg tacaagctca aacattaatg catacagatg tattaattgg
    29581 gcttatgata tttgcagctt taataggatt tataatagat agggtattaa agtttataaa
    29641 taaaatcctt tgtagatgga ggtttgcaga ttaatgaagt taagtgtaag agatataaat
    29701 aagacatttg taaataatag agtacataca aaggttttag aagatataag tatggatata
    29761 gatgatggac aatttgtctg tcttttagga ccatcaggtt gtggaaaaac aactttactt
    29821 actataatag gtgggtttca aaaatcagaa cgtggagatg tttttataaa tgataaaaga
    29881 gttaaaaaac cgggcataga tagagctttt atatttcaaa attatgcttt atttccttgg
    29941 aaaactataa gaggtaatgt tctatttcct atgaaacagc agaaaatacc aaaagaaaaa
    30001 agagaagaaa tgctagaaga acttttggtt atgtcagact tgaaaggaaa agaaaaactg
    30061 tttccgcatc aattatctgg aggaatgaaa caaagagtgg ccatgataag agctttagca
    30121 tgtaatccag aggtattact aatggatgaa ccattaggag ctgtagattt tcaaatgaga
    30181 caaaatttac aggaagagct agaacgaata tggataaaga agaaaataac tgcattaatg
    30241 gtaactcatg atgttgatga agctgtatat atgagtgata gagttatagt aatgtcgaga
    30301 gataaaggaa gaattattga tgatataaat atagatattc caagacctag aattagagga
    30361 agccaaaaat atgaagagta caaaaacaaa ttaactgata ctttatcaaa gtgttatgaa
    30421 gtttaaagag gagtagacat gagtcaaata gaaaaataca atagtttgga taatacacaa
    30481 cagaaaataa gaatctctat tatggatatg ataatagata aaggttctag tgttacactt
    30541 caagaagtga ctgaatatat aagtaaaaag ttgaatatag aaaaagaata tatagaaagg
    30601 acactacaat attttattta taaaaatata atggttgttg atgggaatag tataaatttt
    30661 atatatcctg tatcagcatt gccaacaaat cataaagtaa ctttgagaga taatagaagt
    30721 ttcagtgcaa tgtgtgctat agatgctata ggaacctctt gcacattcaa ccaagatata
    30781 aaaataaact ctatttgtag tgctacaggt aaggaaatag aagtaattat aaaaaatgaa
    30841 aagattgagt atgtgaataa tccaaactta agagtgcttc atataaatct tgataagcat
    30901 ctaaattggg ctgctagttg ctgaaatata atgaatttct tctggacgaa gagtgatttt
    30961 gatgcttgga caaacgaagc gggattatct aatgatgaag atatatattg tttagatatt
    31021 aatgaggcaa tagtagaatc atataaaata tttaaactca aacaaaaggt actatcatag
    31081 atatacatat atgaaaaact aaaaatgacc tttagataaa aatgataggt aatatccata
    31141 ctatataaat tagtatagag tagggatgtg aaaagtattt aaatctaaag gtatattttt
    31201 agtttttttt agatgattag atagccttat taagtatata tttatttata acctttgcaa
    31261 ctccattttc attattagta tcagtaacat aatctgcaat ttcctttata ctattacgtg
    31321 cattccccat agccacacca agacctgcat actttatcat atgttggtca ttttcttcat
    31381 cgccaacagc aatagcattt tctataggta tatttagatt cgtacataat gttttaagag
    31441 cagttccttt attagtagtt ttacctaaaa attctagata aaaaggagca gaccttacta
    31501 tagtatattt attgaataaa tttttaggta gttgctgtat gatttcttcc aatctttctg
    31561 gttcatcaac tatcataatt ttacagattt taatagattc atcaatttta tctttttgta
    31621 tatatttgac ttctatatta tttaatttcg cttcatgaag tgtatatttg ccaggcgttt
    31681 catttggtgt aattaaattt gtcattgtat ttatgtgtat tttagtctta tattttttac
    31741 aaacgttatt atatataaaa tcaaaatcat ctaaactcat ttctacatca tgtatgattt
    31801 tctcactttt aacttcttga ataattgctc cattaaagca tataacataa tcaccttcat
    31861 ctgttaaatt tagttgattt agaagttctt ttacaccagg aagaggtctg cctgttgtta
    31921 taactacttt tgccccagcc ctttttgcct cctgaatgga ctcaaagact tcaggagtaa
    31981 tccttttttg tgtatttaat attgttccat caatgtctag tgcgattaat ttgtacatat
    32041 caacctccaa taaattatat actcaaattt cctgtgaaaa cgttgacaca gctagtgttg
    32101 aacaaagttt cagtgggaaa tatggtttgt tttgtatact attatatcaa gagataagta
    32161 atttagaaag tttaataata ttaatttttt gataaaaata ttacttatgt gagatgagaa
    32221 tgtaaaaact ttgtaatcaa taattccaaa attcttaatt acaaataatg gtatcgtttg
    32281 cattgttaat ataaataaat gtatattata tagttagaag tttgaataaa tagactgatg
    32341 gtaatttgtt atattagtta gttttgtgtt ataaaatatt gtaattccat taatcatatg
    32401 ttattattca acatgattat aatataaaga atatttgata tatataataa tttataaaag
    32461 agtattacat agtacatgta aatctatatt tataaataca ataaagtaaa gttgtaaagg
    32521 agtgctttaa atgaagtttt cagagtttaa gtatgaaaga cccaattata atagtatgaa
    32581 aaaagagttt ttgagttgtg tagaagatat aaataattct cgtaattata aagagcaaca
    32641 aaaaaatata cataagatta atttattaag aaataaaata gaaacgttgt caaatatagc
    32701 ttcgataaga tatagtacag acacatttaa taaattctac aaagaagaaa aaaattattg
    32761 ggatgaatat atgcctttgt atgaagaatt aaattcatat ttttataatg ccattgtaaa
    32821 ttcaaaattt aaatatgatt tgataaaaga gtttggagag caatttttca caatagtaga
    32881 gtattcttta aaaagttttt ccaaagaaat aataagtgaa ttgcaggaag aaaataaatt
    32941 gtgttcagag tatactagac ttttagcttc agctgagata atgtttgatg ggaaaataag
    33001 aaatttatct ggtatgggga aattcatgta ttctaagaat agaaaaacaa gagaattagc
    33061 aaacaaagca tattataatt tctttgaaga aaatgaaact aaatttgatg acatatttga
    33121 taaattggtt aaacttagag ataagatgtc taaaaaatta ggttttgaag attttgtaga
    33181 gcttgggtat gttagaatga tgagaagtga ctacagagaa tatatgataa aaaatgttag
    33241 aaaacaagta ctaaaatatg ttgttccaat ggcaaatgag ctttatgaaa aacaagctaa
    33301 aagaattggt ctagaatatt taagttacat agatgaaggc gtggaatttt taacaggaaa
    33361 tgcaagttta aagggagatt caagatacat aattaaaaat ggtaaaagga tgtattctga
    33421 actgtcaaaa gaaacaaatg aattttttga ttttatgtta gaaaatgaac ttatggattt
    33481 agaaacgaag aaaggaaaag gagctggagg gtattgtact tatataccag attataagtc
    33541 accattcatt ttttctaatt ttaatcaaac tgctgatgat atagatgtat taacacatga
    33601 ggcaggacat gcatttcagt tgtatatgtc tagatggatt gatatgccag aaattaattt
    33661 tccaacgctt gatagttgtg aaatccattc aatgagtatg gaatttataa catggccgtg
    33721 gatggattta ttttttaaag aagatacaga taagtacaaa ttcactcact tatcatcttc
    33781 aattaaattt ataccttatg gagtaattgt tgatgaattt caacactata tttacaaaaa
    33841 tcctaatgta gataagtcaa aacgaaaaga aatctggaga tttttagaga aaaaatactt
    33901 acctcataga aaatatggtg ataattcttt tttagagaga ggttgttggt ggtttaaaca
    33961 aggacatata tttaaaaatc cgttttatta tatagattat gtattagctc aaatttgtgc
    34021 gttacaattt tggaaaaaaa tgattcaaga tagagatgca ggatggaaag attatataaa
    34081 tatctgtaaa gttggaggaa caaaatcatt tttagatatt gtgagtatgg gaaatttgta
    34141 ttctccattt gatgatggct gtattgagtc tattataggt gatgttaaat cttggtttga
    34201 tgaaataaat gacagcaaat tataaaaaat tatgagaatt ttattgtata aaagtgaaaa
    34261 attaaaaaat atataaaaag tgattatttg ttgtgaaaat agtcttgttt ttaactaaat
    34321 tgataaaata aactaaaaaa gatttgtact taaaaaaaaa agaaaataca agaaatatgc
    34381 aatatcaaca tttggaaaaa aaagtaaaaa tgtatacaaa atacatataa aaaaactatt
    34441 gcaaatttta tagaatgttt atatacttaa gtcaacagag atagaaaaaa gctatttata
    34501 gaaaacaaag gataaattgc ttaattttaa attttctgaa aaaaataata atccggatga
    34561 agagtatggg agactgcttt ataaaaagcg accgaaggga caagtttaat cttacttacc
    34621 caaaagatta gatgaaattc tcaggtaaag gtgactgtac ttggacgggg ctctgaaaat
    34681 gattttaaca gggaagacaa attgggagat ttgtttttcc tgttttttat ttatcaagta
    34741 ataaataaaa gtttgaaaga gagtaaaaaa atgataataa ttacgaataa tccaaaagta
    34801 aaagaagaag ttcaaggcag agaagttttg tttaaagaca caacttatat tggaatctta
    34861 gaagcaagta gagatttgat acatgaaggt tatgaacttt tatctcatcc actctatggg
    34921 agtgtaaagc caaatgaaac accttacagg actgttatac taaagaaagg aaatcgtttg
    34981 gatataaact ctttaacctt aattgaagaa gcaatcatca ctgcaagtaa atttcagaat
    35041 aataaaaaga ctccaaaatg gacagaaagt gttcaagatg attttagagt aattgattat
    35101 gatatatttt ataatacaat acaaagaatg cagtatgaat aaaaaaaaat tgttaaaaag
    35161 ttattaaaac agcctaaata ttaaatctaa tttaatatta aataaaatga gaaatttaat
    35221 tggggaggat aagtcaaaat ggaaaatgtg tatgacttag taataattgg ttcaggacca
    35281 gcagggcttg cagcaggtct ttatggagca agagcaaagt taaaaactct aatcctagaa
    35341 aaagacaaga ctggtggaca aattgtaata acacatgaaa ttgcaaatta tccagggtca
    35401 gttccaaatg caacaggacc aagtttaata gctagaatgg ttgaacagtg taaagagttt
    35461 ggagcagaaa tgctaagaga caacattgtt gatactgagc tagatggaga tataaaagtt
    35521 ttaaaagggg aaaaggcaga atatagagca aaagcagtaa taataggaac aggagcaaca
    35581 ccaagaaaga ttggttgtcc tggagaaaaa gaacttactg gtaaaggggt ttcatattgt
    35641 gcaacttgtg atgcagattt ctttgaagat tttgaagtat ttgttgtagg tggaggagac
    35701 agtgcattag aagaagcaat gtatttaact aaatttgcta gaaaagtaac aattgtacat
    35761 agaagacaag gatttagatg tgctaagagt gttgaagaaa aagcaaaagc taatccaaag
    35821 atagagtttt tattagatac agtaattgaa gaaatcaaag gtgatggaat attagaatca
    35881 gttgtattta aaaataaagt tactggagaa actcatgaat actttgcaga tgaagaagat
    35941 ggaacaatgg gagtatttgt gttcgttgga ttagatgctc aaactgattt attcaaaggt
    36001 aaagttgata tggatgaaaa aggttacata ataactgatg aagatatgag aactaacata
    36061 ccaggcgtat ttgcagcagg agattgtaga tctaagactc taagacaggt tgtaactgca
    36121 actaatgatg gagcaattgc atctatagta gctgagaaat acattgatga aaaatttggg
    36181 aactagaatc tgtaaattaa gaaatagtgt ctgtaaattt aatgaataat atttaaaatt
    36241 aaaattaata tttaaaatta aaataaaaat ttcaaggggg aataagaaaa tgttagattt
    36301 agataaggct acatttgaag aagaagtttt aaatgcagaa ggttttgtat ttgttgattt
    36361 ttggagtgaa ggttgtgagc cttgtaaagc tttaatgcca gatgttcata aattagctga
    36421 gacttatggg gataaaataa aattctgtaa gatggataca acaaaagcta gaagattagc
    36481 tataaaacaa aaagtattag gtcttccaac tatggctata tacaaagatg gagaaaaagt
    36541 agacgaagtt actaaggatg atgctacagt tcctaatata gaaaacatga ttaaaaaata
    36601 tctttaatat gttgataaat tattaacatt aaaagaaaaa atctattttt atctgaagat
    36661 aagaagaaaa aggtttttat gtccaacttt gttaaaaaaa taattttaaa taaaataatt
    36721 tttttacaat aaatattttt tagtaataaa ataaagattt aaggcataaa aacacaataa
    36781 tatatcttta aaaaaataag ataaattgta aaatgatata attttgagaa aaactcaaat
    36841 gcatatacac aaattaaata acaggaggtg caagtatgcg tcttgaatta gggaaaatct
    36901 ttataaaaga tattcaattt ggtgatgtaa cagaagtaaa agatggagta ttattcatca
    36961 ataagcaaga gatgctacaa gaaattggtg gagatgagca tattaaatct atagatatag
    37021 aattagctcg tccaggtgaa agcgtaagaa taacacctgt aaaagatgtt attgagccaa
    37081 gagtaaaagt tgaaggtaat gggggaatct tccctggtat catgtctaaa gttgacactg
    37141 taggagaagg aaaaactcat gctttaaaag gtgtagctgt tgtaactact ggaaaaatag
    37201 taggtttcca agaaggtata atagacatga ctggagaagg agctaagtac actccatttt
    37261 ctaaattaaa taatgtagta gtaatagctg aacctattga tggtttaaaa caatacgctc
    37321 atgaaaaagc tgttagaatg ataggattca aagcagcaat gtacttagga gaagtagcaa
    37381 gaaatcttac tccagatgaa gtttcagtat atgaaactaa acctcttctt gaatcaataa
    37441 aagaatatcc agagcttcca aaagtaggat atgtttacat gcttcagact caaggtttat
    37501 tacatgatac ttatgtatat ggagtagatg caaaacaaat agtaccaact ttattatatc
    37561 caacagaatt aatggacgga gcaattgtaa gtggtaactg tgtttctgca tgtgacaaaa
    37621 acccaagtta tgttcatata aacaatgggg ttgttgaaga cttatatgca agacatggta
    37681 aagatataaa ctttgtaggt gtaattataa ctaatgaaaa tgtttatcta gcagataaag
    37741 aaagatcttc aaactggact tctaaattat gtaaatattt aggattagat gcagttatag
    37801 tttcacaaga aggttttgga aatcctgata ctgaccttat aatgaactgt aagaagatag
    37861 aaatgcaagg tgttaaaaca gttatagtta cagatgaata tgctggacgt gatggaggtt
    37921 ctcaatcact tgcagatgca gatgtaagag ctgatgctgt tgtaacaggt ggaaatgcca
    37981 accaagttgt agttcttcct aagttagata aagttattgg acatttagaa gtagtagatg
    38041 taatagctgg tggttctgat ggaagtttaa gagctgatgg aactattgaa gttgaaatcc
    38101 aagctataac aggtgcaact aatgaaacag gatttggtca tttaactgct aaaggatatt
    38161 aagaagtatt ttattaaacg attgagtaat gttaataaaa catattatag ataattataa
    38221 taagtgttat agatatataa aaatatatta gaaatataat aaggaggatt attatgagtt
    38281 tacttagtaa taaaaaggtt cttataatag gtgaccgtga tggtatacca ggacctgcga
    38341 tagaagaatg tgtaaaaaca gtagaaggag cagaggttgt tttctcatct acagaatgct
    38401 ttgtctgaac agctgctggg gctatggact tagaaaatca aaacagagtt aaagatgctg
    38461 ctgataaatt cggagctgaa aatgttgtga ttttactagg tgctgctgaa gccgaagctg
    38521 caggtcttgc agccgaaaca gtaactgctg gagatccaac tttcgctgga ccacttgctg
    38581 gagttgcctt aggattaagt gtttaccacg ttgttgagga accaataaaa tcattatttg
    38641 atgaaagtgt atatgaagac caaataagta tgatggaaat ggttttagaa gttgaagaaa
    38701 tagaagaaga aatgtctggt ataagagaag aattttgtaa attttaatgc ctaaaagcaa
    38761 aaggggtgaa actaagagat gggaaaacta aaagcagtac attatattaa tcagttcttt
    38821 gctggtatag gtggagaaga aaaagctgat actaagccac atgtggcaga aactttacct
    38881 ccaataagtt tacaacttga taaattatta ggtgaagata ttgaaatagt tggaacagta
    38941 gtttgtggag atagctattt caatgaaaat atagatagtg caagtgaaga agttttatca
    39001 atggtaaaag gttttgaacc acaacttttc atagctggtc ctgcatttaa tgctggtaga
    39061 tatggggttg ctgctggaac aataactaaa gttgtaaaag atgctttgaa tataccagct
    39121 ttaacaggta tgtatgttga aaatccagga gcagatatgt tcaaaaagga tgtttatgta
    39181 gtagaaactt ctgattctgc agcaggtatg agaaaggcac ttcctaagat agctaaactt
    39241 gcagtaaaac ttgctaatgg agaagaaatt ggaactccta aagatgaagg atacatagct
    39301 agaggaataa gagttaacta cttccatgaa gacagaggtt ctaagagagc tgttgacatg
    39361 ttagttaaga aaataaaagg tgaaccattt gaaactgaat acccaatgcc aaactttgat
    39421 agagttgacc caagtaaagc tgtaaaagat ttatcaaaat gtaaaatagc tttagttact
    39481 tctggtggta tagttccaaa aggaaatcca gatagaatag agtcttcttc agcttctaaa
    39541 tatggaactt attctatagc aggagttatg gatttaacag aagagactta tgaaactgca
    39601 catggtggat atgacccagt gtatgcaaat ttagatgcag atagagtatt acctgttgat
    39661 gttcttagag atttagaaaa agaaggtgta attggaaaat tacatgagac tttctataca
    39721 actgtaggta atggtacatc tgttgcaaac tctaaaaaat atgcttctga aattggagca
    39781 gcattagtgg ctgatggtgt agatgcagta atattaactt ctacatgagg tacttgtact
    39841 cgttgcggtg caacgatggt aaaagaaata gaaaaaactg gacttccagt agttcatatg
    39901 tgtacagtag tacctatttc attaacagta ggggctaata gaatagttcc aactatagca
    39961 atacctcatc cacttggaaa tccagcgctt gaccctacag aagaaaaagc cctaagaaga
    40021 ggccttgtag aaaaagcatt aaatgcttta actacagaag tagatggtca aacagtattt
    40081 gaaaaataaa aataacacac acatatatta tatagataaa aatataaaca cacactaaaa
    40141 ataaaaaata actatacaca aaaaaataat atagatttca tgaatggata aattggagtt
    40201 attcattcat gaaatcttaa aaaatgccaa aatacataaa caataataga atcaaatata
    40261 caataaaata caatgattag agcttttaat aagtttaata agattaaaaa ataagtgttc
    40321 ataaaattta tggaggtgca caaaatgact tatccagttt taaaaggggc aggctatgta
    40381 cttattcata ctccagatat gatagtgcaa aatggaagta cttgtacagt tgaaagagca
    40441 acaaatccag attcagaatt tttaaaagaa gtaagtaatc atataagaag ttatgaagat
    40501 gtagttaact acatgccaaa tcaagtttat ataggaaata gaagaccaga agaattaaga
    40561 gatttaccaa tgccatggtg tgaacaaaag attgagggaa ctagaaatgg taagtttgga
    40621 gaaataatgc ctcaagatga gttcatagct ttaatgcaaa taagtgatgc atttgattta
    40681 gtaaaattat cacaagaatt tattgatgaa gtaaagccaa aaatcgaaaa taactaccct
    40741 gaaattgcac catttgtagg taaattaaag ggtgatgata tagaagaagg taaagaatta
    40801 gtagcaacac acatagctga aggattatac catgatggaa aatttgttgg ttatgtaaaa
    40861 agagcacatg atgtagatgt taacttaaat gcccatacaa tgtttgaaaa tctagtagta
    40921 aaagcatctg gagttttatc tgctattcaa atgctaagac atagcaaaat agaccctgct
    40981 gaaatagatt atgttattga gtgttcagaa gaagcttgtg gagatataaa ccaaagaggt
    41041 ggaggaaact ttgctaaatc aatagctgag atagcaggac ttcaaaatgc aactggttct
    41101 gacacaagag gattttgtgc agcaccaact catgcattaa ttcaagcagc agctttagta
    41161 aaagctggca tacataaaaa tgtaatggta gtagcaggtg gagcaagtgc taaacttgga
    41221 atgaatgcta aagaccatgt taaaaaaggt cttcctgtac ttgaagatgt tgttggagga
    41281 tttgcagtac ttgtatctga aaatgatggt gtaaatccag ttataagaac tgatttaaca
    41341 ggtaagcata ctgttggaac tggttcttca ccacaagcag ttatgacagc acttataact
    41401 tcaggtcttg atagagctaa tttaaaaata acagatgttg atgtgtattc agttgaaatg
    41461 caaaacccag atataactaa gccagcagga gcaggagatg ttccagaagc aaactacaaa
    41521 atgatagggg cacttgctgt taaacgtgga gacttagaaa agaaagaatt gaaagatttt
    41581 gtttctaaca aaggattacc aggatgggca ccaactcaag gacatatacc atcaggagct
    41641 ccttatatag gatttttaat agatgattta actacaggaa atagaaatag agctatgata
    41701 gttggaaaag gtagtttatt cttaggaaga atgactaact tatttgatgg agtatctttt
    41761 atagctgaaa gaaatacagg tgttactgaa gagacttcag gaatatctaa ggatgaaatt
    41821 aagaagataa tagctgaatc tatgaaaaaa ctagcattag atatgttaga agaatagggg
    41881 tgaggatatg tcaaaaaaag taatcgcaga tgtattctta gaagtagcta atgcaataga
    41941 aagcggcgaa tttggcaaaa aagtaaaaat tggtgttact acacttggaa gtgaacatgg
    42001 tgtagaaaac atggttaatg gtgcacaatt agcaaaatct aatttatttg atattgtgct
    42061 tattggacca aaagtggaaa ctgaccttga agtagttgaa gttaatgatg aaaaagaaat
    42121 gcatgcaaaa atggaagaat tattagattc aggatatatt gatgcttgtg ttactatgca
    42181 ttataatttt ccaataggtg tatctacagt aggtagagta ataactccag caaaaggaaa
    42241 agaaatgata cttgcaacaa caacaggaac aagtgctact aatagaatag aggcaatggt
    42301 aagaaatgcc atttatggta ttgctacagc taaatcaatg ggtaacaaat gcccaaaagt
    42361 tggaatactt aatgttgatg gagcaagaca agttgagaag tgcttaaaag aattaaaaga
    42421 taatggatat gacatggagt ttgcggattc aattagagca gatggtggat gtgtaatgag
    42481 aggtaatgat ttacttgtag gtgcacctga tgttatggtt actgatacat tatctggaaa
    42541 tatatttatg aaagtatttt cttcatatac tacaggtgga gattatgaag ctcaaggctt
    42601 tggatacgga cctggagttg gagaggacta tgatagaaag gtacttatag tatcaagagc
    42661 atcaggttct ccggtagtag caaatgcttt aaaatacgct tatgatgttg taaagggaga
    42721 tataagtaat gttgcaagaa atgaatttgc aaaggttaaa aaagcaaaat ttgatgacat
    42781 tatatcctct cttactaaaa aagaagttaa agctgaaaaa gtagaagtta aaatgccaga
    42841 taaagaaatt gttactcgtc aaatagctgg tgttgatata atggatttag aagatgcagt
    42901 atctgagtta tggaaaaacg gaatctatgc tgaaagtggt atgggttgta caggtccaat
    42961 agttttagta aatgaagcta aaggagactt agcagttgaa actttagtta aagctggata
    43021 tactgcaaaa taagtacatt ttttatatgt aaataagaac atatagttat aattttattg
    43081 attataatta tatgttcttt ttattttata tcttgtcaat atttatatat taacacaatc
    43141 catttatttg attctctagc taatttatta tatttattca attaaaatta agctttctaa
    43201 ctaaataaaa actaatgaag tattaaaatg aaattgataa aatatgaaaa aattttagga
    43261 ataaagtatc tgttagataa aaataagatt aattagtgat ataatataat taagataaaa
    43321 tttattattt ggaggtaaaa tcatgagcag agtaaaaaat gtagtagaat tgttggaaac
    43381 taaaggtgtt gatgcactat atctaacaaa gaaaactaat gtaaactata taagtggttt
    43441 tcctgatgaa gaagcatatg cagtgatttg caaagatgga aactttttag ttactgatag
    43501 tagatatatg gagcttgcag aaaaggtttg caaagatttt gaaattataa attggcataa
    43561 ttttgataga agtgtggcaa aggcagttaa aagtgtatgt gataaagtgg gtataaagaa
    43621 acttggattt gaaagaacta atatagtgtt tgataaatat gaagaactta aaaatctgat
    43681 tgagaaggat aatggagaat taatacctac agaaaatatt gtagagactt tgagatatgt
    43741 aaaagacaaa gatgaaatca aaaatacaag aaaagcttgt gaaatagcgg ataaggcatt
    43801 agaagaattg attccacata taaaagctgg agttagcgaa attgaactgg ctacaaggtt
    43861 agagtacttt atgaaaatga acggagcaca aaatataggg tttgaaacta tactgatatc
    43921 aggagcaaag acttcattgc ttcatggtaa gcctagtgat aagattatag aaaaaggtga
    43981 ttttgtactt atagactatg gtgctatgta taatggctat atatctgata caactagaac
    44041 ttttatagtt ggaggagctt ctgaaaagca attagaaata tataatttag ttaaggaagc
    44101 tcaaaatgta ggggttgaga acatgaaagc tggtgtacat gcgacaattc cagatgctga
    44161 gataagaaaa gttgtcaaaa aatatgaaga ctattactat caaggtatag gacatggagt
    44221 cggtagagat gttcatgaag aacctttcat tggtaattat ggtgataaaa tcatagaaga
    44281 gggatgtata ataacaatgg aaccaggtat ttatttccct ggatggggtg gagttagaat
    44341 agaagatact gttttgatta ctaaaaatgg tccagaaaga cttactaaat tccctaaaga
    44401 tttgatgatt ttagacaaat aatttaattt atatatattt ttttacataa aatataacat
    44461 aatctcacta ttaagctcta tttacatatt atagtaaaga gggcttaatt ttattgtgag
    44521 aggtgatagt atatatgtat aaaaaacata aatttataaa aaatataaaa aaagcctggt
    44581 ataaaatcaa attaattgat agatgcctta taattgtaat ggcaatatta atgtttcaat
    44641 ctatatataa cttatttgtt aatgaagtaa attcacaaga tactacaact attgatgtag
    44701 tagtaagaac cacttcagca gctatatttg ggtatttttt aagtgctaat tttataaaga
    44761 gacctttaag gaagtataca aatactgatg tatcttcaaa tctttttata gataataatt
    44821 tatccccaaa aggtcaagag tctaatcaaa ataatataat gaatgtcaaa aataccattg
    44881 gatttacttc agaagctgat aattatgaaa agaaaatacc tattaataat aatgaaggtt
    44941 ttgaagaagg agaaactagt gaattgcaaa ttattatagc tactgtaatt tgcatagtag
    45001 cattaacagt actttttgtt gtaagaaatt ttacaactac aacatcagct tctttaggta
    45061 ctatttcaca gatgagagat tttgtctcag gatgcgtggg ttttttgcta ggttgtccaa
    45121 gtaaacctga ttaaaaaagt attatcaata aaaggtattt taaaaagtat cagtataata
    45181 atatttagat ttaaatgtat acaattataa ttctgtaaca ttctatattg tatttttata
    45241 ctgatactct aaactatact atttattaaa atattttaac attgtattta aacaaaatat
    45301 tatatctgta taatataaat ttagtttata tgaatagatg ccatatactc aataaaaagt
    45361 ttcatactat gagatatgta ttgatttctt ctccaaagaa ccccaatatt tgcagtaatt
    45421 gcacgttcta atggtattga acagagattt tctgtatttt gaaatatttc tttatacaat
    45481 attgttgaag ccaagtcatt ttctagtaaa taacgtatgg tagaaagttg atttgagtgt
    45541 aaaattatat ttggcttagc tttttcaagt ctttttgtaa taatcttata gtgataagaa
    45601 ccttcagata agattacaaa aggtacattt tttaacatat aattcgatat aataggatgt
    45661 tttgccaatt catttttggg atttgtaact aagtataatt ctgttttata gattgtcttt
    45721 gaatctatat catcataaat atcactgtca attataccaa tacaaaaatc aagtgtagat
    45781 tcttcaatca ttttagctcc aacaaatgtt ggaacttcaa aaattttaag ctctatatct
    45841 ggataaatta cattaaacct aggaagtatt tttgaaagca aaaacgtacc taaaactgta
    45901 ggaataccta ttttgagaga agcttttctc ttttttccta aatcaagtgc gtcacattga
    45961 aaatcctcaa attgttttat aaaatgtttt gacttgtcta aaaaaatttt tccttcaggc
    46021 gttaactcta ttttattacc tattctgtaa aaaagttcaa agccaagttc tttttctaat
    46081 tctttaattg ctaatgttat ggatggttga gaaatatgaa tactttccgc agccttagtc
    46141 atgtttttat atttacagac agtttgaaaa tagtataaat agtttatatt catttggtat
    46201 tagttccttt catttacata ttagtgacaa gtatataatt aacaatagca taagttttgt
    46261 atattgttgt aaaaaaatag aatagtttta aactatcata gcataagttt ttgatatttt
    46321 caatctatta agaatagtgc tattattaaa ttaacaaaag agaatagctg gtatggttta
    46381 gagtaaatca atctatatta cagttatatc aacgaatatc aaaaaattat ctattaaaaa
    46441 ataaaaatta tttttacaat taaattgtta attaaatcat aaagaaaaaa gtgatattaa
    46501 caagataaaa tttttttaat cagaaatgtt aatttaataa caaaatagag tattggggag
    46561 aaaggagaaa tatatttttt aataatattt gttaatttaa taacgaaaaa tgaaagggag
    46621 tgatttagtg aagtttgaat tgatggattt tttaatgaat ccttttgtcc ttatgtttgc
    46681 tgcagtaatt acaggaattt tatttggaaa aattaaattt gggaagttta attttggggt
    46741 atcaggagca ttatttacag gattatttat tggatggctt gcatatagct tggggaatct
    46801 aataatagca aaaggggaaa cagcagcagg atataaggca gcaactgtaa tgatggggaa
    46861 tggaattatt tcttctgact tctttgattt ctttttaata atatttgttg cagcagttgg
    46921 tctattggca gcaaaagata tgaaagctgt attaaagaag tatggagcaa gatttgtaat
    46981 tttaggagtt cttataactt ttataggtgg ctctatgact tatgcaatga ctttactatc
    47041 aagtgataaa ggaagtagtg cttatgaagt ttctggcgtt tacacaggag cattaacaag
    47101 ttcgcctgga ttagctgctg ctttagaaac agctggtaaa catgcagaag atgtatcaaa
    47161 agaatttgaa aaagcttcaa taaaagataa aaaagaaatt ttaaaagtag tcgacccaga
    47221 aggcaaattg gatgtgaata caactacatc actgactcaa gagcaaatag ataagtatat
    47281 tgcatatgct gaagctggtg ttggtatagg tcatgcagtc gcatatcctt ttggagtttt
    47341 aatagtaatc ttaggtgtaa atttccttcc aaaattattt aggatggacc taaaagaaga
    47401 aagaagaaaa tatgagaagg aaatgaagga agcaagagat agtgtttctg gtaaaacgat
    47461 accagaagtt ccatttaata taataacatt tttcttgaca tgtttagctg gatacttagt
    47521 tggaggaata catgtattta tgggaccact agggtacttc acactaggtg caacaggagg
    47581 ttcactaatt gtatctctag ttcttggata tataggtaag ataggggtag taaatttcag
    47641 aatggaagaa aaggttttaa atattttaaa acaaataggg ctagtgtttt tcttagcaat
    47701 agttggatta agatatggtg gaaaagtagt tgattcaatt atgacatctg gtatgcacct
    47761 agccttagta gcaatagcag taggtgttac agctatgatg ataggattct tagttggcaa
    47821 atacgtattt aaattaaatt ggattttatt atctggagct gtctgtggtg gtatgacatc
    47881 aacaccaggt cttggagctg ctgttgatgc tcttgatagt gatgacccag cagcaggtta
    47941 tggtgctacg tatccatttg cattattaac taaagttata ttggttatag ttttacacaa
    48001 acttccaatg taaataagat tttatatggg gggatattta tgaataatga aggagcattt
    48061 gaagaattaa gtggaagatt aagaaataaa gaattgtgtg atttaataat gaatgcagat
    48121 gaagctgcta aaattataga ggatggcatg gttattggag ttagtggatt tacaccttca
    48181 ggctatccaa aagcagtacc attagcagtt tcagaaagag ctaaaagtgg agaaaagata
    48241 aaattaaccg tatattcagg agcatcttta ggtccagaag ttgatggagc atggtcagaa
    48301 gcaggtataa ttgaaagaag acttccttat caaactaatt caatacttag aaataatatt
    48361 aataaaggtg ttgttgatta tatagatatg cacctaagtc attctactca atttttaaat
    48421 tatggaacta tacctaaagt agatgtagct atagtagaag cacttgcaat aactgaagaa
    48481 gggaatatta taccaactag tgggataggt aattctccat cttttataaa aagtgcagat
    48541 aaagtaatag tagagataaa tcttgcaaaa ccaatggaaa tggaaggtat ggcagatata
    48601 tatattacgg aaaatccacc aaatagaaaa ccaatagaaa taaatcatcc taaggataga
    48661 attggaacaa catatatacc ttgtggtttg gataaaattg caggagtagt aattaccaat
    48721 atgcaagata agacccgtcc attgggggtt gtagatgaag cttcgaaaaa aatatcaaat
    48781 aatattattg cttttttaag agaagaagta aagtcaggca gattatcaaa gaatttactt
    48841 cctcttcaat ctggtgtagg aagtgtagca aatgcagtat tatatggatt atgtgaatct
    48901 gaatttgaaa atttaacttg ttatacagag gttgtacagg actctatgtt ggatttaata
    48961 agaatgggta aagttacaat ggcatctact acatctgtaa gtccatctcc agaaggatta
    49021 ataaaatttg aaaaagatat tgattttttt aaggataaga ttatattaag acctcaagaa
    49081 attagtaaca atccagaaat agccagaaga attggtgtaa ttgcaatgaa cactgcaatt
    49141 gaagttgata tttatggaaa tgtaaattct actcacataa tggggtcaaa gatgatgaat
    49201 ggaattggtg gttctggtga ttttgctaga aatggagcaa taactatatt tagtactgag
    49261 tcaattgcaa aaaatggtga tatatcatca atagtaccta tggtatctca cgtagaccac
    49321 actgaacatg atgtaatggt aattgtaaca gaacaaggat atgctgattt aagaggtctt
    49381 gcacctagag aaagagctat aaaaataata gaaaattgtg cccatccaga ttataaagaa
    49441 caacttaggg attatttaaa tagagcttgt aaaagtggag caaaacaaac acctcacata
    49501 ttggacgaag ctttatcatg gcatagtaaa tttatgagta caggtacaat gaaaaaggct
    49561 gaaactttta aaagtgcatt ataaaatatt taataaattg gaggtagatt ttaaatggaa
    49621 aaagcagtgg aaaactttga agatttaagt aaggaataca ttaatggtta tattgagaga
    49681 gcaagaaaag ctcaaagaga gtttgaatgt tatactcaag aacaagtaga taaaatagta
    49741 aaaatagttg gaaaagtagt gtattataat gctgaatatt tagctaaact tgctgtagaa
    49801 gagactggaa tgggagtata tgaagataag gtagctaaaa ataaaagcaa agcaaaagtt
    49861 atatataaca atttaaaaga taaaaaatca gttggtataa ttgatataga tagagaaact
    49921 ggaataacaa aggtagctaa accagttgga gtagtagcgg caataactcc ttgtacaaat
    49981 ccaatcgtta cacctatgag caatgcaatg tttgcactta agggaagaaa tgcaattatt
    50041 atcacacctc atcataaagc aattggatgt agtacaaaaa ctgtagagat gattaatgaa
    50101 gaattagaaa aaataggagc tccagaaaat ttaatacaaa tacttgacca acaatcaaga
    50161 gaaaatacaa gaaatttaat ttcatcagca gatgtagtaa ttgccactgg aggaatggga
    50221 atggtaaaag ctgcgtactc aagtggaaaa ccagcacttg gtgtaggggc aggaaatgtt
    50281 caatgtatca tagatagaga tgtagacatt aaagaagcag tacctaaaat catagcagga
    50341 agaatttttg ataatggtat catttgttca ggtgaacagt cagtaatagt agcagaagaa
    50401 atgtttgata aaataatgga tgaatttaaa aataataaag gttttatagt tagagataaa
    50461 gtacaaaaag aagctttcag aaatgctatg tttgtaaata aatctatgaa taaagatgca
    50521 gtaggtcaat cagttcatac aattgcaaaa attgcaggtg ttgagatacc agaagataca
    50581 aaaataatag taatagaagc tgatggacca ggagaagagg atattattgc aaaagaaaaa
    50641 atgtgtccag ttatatctgc atacaagtat aaaagttttg aagaaggtgt agctattgca
    50701 aaagcaaatt taaatgtaga aggaaaagga catagtgtat ctatacattc aaatacagtt
    50761 aaaaatatag aatatgcagg agaaaatata gaagtatcaa gatttgttat taatcaatgt
    50821 tgtgctacta gtgctggagg aagtttcttt aatggtcttg cacctactaa tactctaggt
    50881 tgtggttctt ggggaaataa cagcatctct gaaaatcttg attataagca tctaattaat
    50941 atttctagaa ttgcttatta tatgccagaa aatgaagtcc ctacagatga agaactttgg
    51001 ggataaaatt tagacaaaaa atattcattc taaattaaag taggaatata ttttaattta
    51061 gaatgaattt aagacataaa ttaaatttaa attagtttat tggactaaat ttaaaatatt
    51121 aagagacata tagaagaagg aagtattata atttaaaata aataaaaaaa tctataaaag
    51181 agaaggagtg gttttattat ggcattaatg acaggagctc aatatattga aagtttgaga
    51241 aaattaaata ctaaggttta tatgtttggt gaagaggtta agaattgggt tgaccatcct
    51301 atgattagac catctataaa ttgtgtagca gcaacttatg acttagctca tgacccagaa
    51361 tatgcagatt taatgacagt tacttcaaat atcacaggtg aaaaaataaa tagatttggt
    51421 catcttcatc aaagtgttga tgatttgata aaaaaagtaa aaatgcaaag actatgtggt
    51481 caaaaaacag cttcttgttt ccaaagatgt gttggtatgg atgcgtttaa tgcagtgtat
    51541 tcaacaacat ttgagtgtga taaagcccat ggaactaatt atcatgataa ttttgtaaaa
    51601 tacttaactt atatacaaga aaacgattta gtagttgatg gagctatgac tgaccctaag
    51661 ggagatagaa gtctatcacc tagtgctcaa cctgacccag atatgttcct tcatatagta
    51721 gaaagaagag aagatgggat aattgtaaga ggagcaaagg cacatcaaac tggttcaata
    51781 aattcacatg agcaccttat aatgcctact ataagtatga ctgaagcaga taaagactac
    51841 gctgtatcat ttgcagttcc ttcagatgct gaaggagtgt ttatgattta tggaagacaa
    51901 tcttgtgaca ctagaaaatt agaagaaggt gcagatgttg atttaggaaa taaggagttt
    51961 ggaggtcaag aagctttagt agtatttgat aatgtatttg ttccaaatga tagaattttc
    52021 ttatgtggag aatgggattt ctctggtatg ttagtagaga gatttgcagg ataccataga
    52081 caaagttatg gtggatgtaa agtaggagta ggtgatgtaa taataggagc agcagcttta
    52141 gcagctgatt ataatggagc aaacaaagct tcacatataa aagataaact aatagaaatg
    52201 actcacctta atgaaagctt atattgctgt ggtatagcat gttcatcaga aggtcacaaa
    52261 acagaagctg gaaactatca aatagattta cttcttgcaa atgtgtgtaa acaaaatgta
    52321 actagatttc cttatgaaat agtaagactt gcagaagata tagctggagg gcttatggtt
    52381 actatgcctt cagaaaaaga ctttaaatca gaccttaaag ttggaacaag tggaatgact
    52441 attggcgaag tatgtaacaa gtattttaaa gcttcttcag tggcttcaac agaagaaaga
    52501 atgagaatat taagattctt agaaaatata tgccttggtt catctgctgt tggttataga
    52561 actgagtcaa tgcatggggc aggttcacca caagctcaaa gaataatgat ttcaagacaa
    52621 ggaaacataa atcaaaagaa agaattagct aagaaaattg cgggaataaa aaaagaggaa
    52681 gctttaaatt tataaaaagt tgatatataa agggaaatta tatattaatg tgtattaatt
    52741 aatgaaaaaa tatgtagtat aagagatagt tataaaatta tggtggtttt tagctaagta
    52801 aagaaatttt taataaggag aatttacaca tgacctgtgg agttagattt tgtgggggct
    52861 gtaaccctag atacgaaaga gggaaggctc ttacaataat caaagagcac ttcaatggta
    52921 gggtagattt tagtatagca caagagaacg tcgagtatga tttgctactt ataattggag
    52981 gatgcgcaac tctatgcgca tcctatcaac aatataaagt gaaaaatgaa tgtgttaaga
    53041 tgtgggattt tagccatata gaaagagtta taaatgtgat tgaatcagca atttgtgaaa
    53101 cttaaaaaag ctaaatgggg ggatttcatt gagttggcaa gaattgtatc aaagtaaatt
    53161 atgtagtgct acagaagctg taaaacagat taaaaacggt gatactgtag tatttgcaca
    53221 ttgtgtaggt gaacctcctg cactagtaga ggctatgatt gaaaatgctg aacaatataa
    53281 agatgttgag attaaacata tggtaagctt gggtagtggt ggatatactg ctaagggaat
    53341 ggaagctcat tttagagtaa atccaatgtt tgtaagtgga aatgtaagaa aggcaattga
    53401 aaatggagat ggtgatttta cacctgcatt cttccatgaa gtaccaaagt tgcttagaga
    53461 aaaaagatta aaatgtgatg ttgttttagc acaggtaact ccaccagatg aacatgggta
    53521 ttgtagctta ggaacatcag ttgattatac ttatgaagcc attaaaactg ctagaacagt
    53581 aattgttcaa gtgaatgacc agtttcctag aacctatggt gaggtagtcc atgtatcaga
    53641 gtttgactat atagtggaaa aatcacaacc tttatttgaa ctacaacctg caaagattgg
    53701 agaagtagaa gaagcaattg gtaaaaattg tgcttcatta attgaagatg gttctacttt
    53761 acagctaggg attggtggga taccagatgc agttatgtta tttttaactg ataaaaagga
    53821 tttagggatt cattcagaaa tgatttcaga tgggactttg gccctttatg aaaaaggtgt
    53881 tataaatggt aaatataaaa attttgataa agaaaaaatg acagttacct tcttaatggg
    53941 tactaaaaaa ttatatgact ttgcaaataa taaccctgca gtagaggtaa aaccagtaga
    54001 ctatgtgaat catccagcaa ttataatgaa acaacataag atggtttcta taaattctgc
    54061 tatacaagtt gatttaatgg gacaggtagt tgcagaggct atgggactta gacaatttag
    54121 tggtgttgga ggtcaagttg actttatacg tggagtgtct atgggtgaag atggaaaggc
    54181 aattatagct atgccttcaa taactacgaa aaaagatggt acagtaattt caaaaatcgt
    54241 gtctattgtg gatgaaggtg cacctataac gacatcaaga aatgatgttg actatattgt
    54301 aacagaatac ggtatagcag aattaaaagg aaaatctctt agagaaagag cgagaaattt
    54361 aataaatata gctcatccaa gtgtaagaga aagtctagca gtagaatttg aaaagagatt
    54421 taaggagaaa tattaataat agaggggtgt taataatgga agcacttaga gtagttccaa
    54481 agatatttta ctttgataca tttaaagaat ttaatgaaga atttaaaata ggaaaaaatg
    54541 atttagtaat tactaatgag tttatatatg agccatatat gaaacctctt ggaatagata
    54601 caaatttaat ttttcaagaa aagtttggaa caggtgaacc atctgatgaa atgatagact
    54661 ccatgacaaa ggaaatgaag aaatacaatt ttgatagaat tattgcattt ggaggaggaa
    54721 caatagttga tatatgtaag atattagcac ttgatgttcc agaaaagtct attgatttat
    54781 ttgaaggaga agtatcacct aaaaaagtaa aagagttagt agtagttcct acaacatgtg
    54841 gtacaggtag tgaagtaaca aatgtagcta ttgcagagtt aaaatctaaa catactaaaa
    54901 aggggcttgc agtagaagaa acatatgcag actatgcagt gttaattcca gagacagtaa
    54961 aagggttacc ttacaaattc tttgttacaa gttcggtaga tgctcttata catgctattg
    55021 agtcttatct ttctccaaaa gcaagtccat ttacagagat gtattctcta caagcaataa
    55081 aaatgattat ggatgggtat aagaagatag ttgataaagg agaagaagag agatttaatc
    55141 atcttagaga ctttgtactt gcatcaaatt atgcaggaat tgcttttgga aatgctggtt
    55201 gtgcagcagt tcatgcacta tcttattcaa taggtggagc tttccatgtt gcacatggtg
    55261 aagcaaatta tcagttcttt actgaagtat ttaagatgta ttctagaaaa aaacctaatg
    55321 gaaaaattat aaaatgtaca aaaattttag cagatgccct tgaatgtgac cctaactgtg
    55381 atgtttatgg agaattagaa aagtttttaa ataaattaat agctaaaaaa gctttgagag
    55441 aatatggaat ggtggaaagt cagatagatg aatttacaga tagtacaata gcaaatcaac
    55501 aacgactact tgctaataat tatgtagagc ttagtagaga ggaaataaga gagatatttg
    55561 caaatcttta ttaatacaat tttttattta tatgtatagt caacataaac aatgctaatt
    55621 atatttatgt acaaataaaa ataagggaac ttaaatttta attaaagtta agttctctta
    55681 tttttatatg gagttaaata taagtatatt tttaatttaa aatatgctta tatttaagtc
    55741 tattacttta tttgaaacaa tttgtagaat ttcaaattcc ttgacagtaa taagtaagta
    55801 attgtataat caaactgcaa tatattaata atattagtga aaatgaaagg attataaaat
    55861 atgtataaat cagaaaattt ttcaaaaaaa tctgtattaa taaattcatt tttaagtaaa
    55921 tttttaaaaa taattggatg gggtttggta agcttattta cattatcagc cttagtactt
    55981 tcaactattt ccattataat tggatgggct gtaatacttc ctattcaagt atgtgcagta
    56041 tttttactta taggaggagt ttgtattttt aaaggtaaga gattaggaga ccaaatttct
    56101 cgttataaaa aatattgtac aattataaac aatagaaata ttattccagt agaacttatt
    56161 gcagaaaaca catctaaatc attaaatttt ataataaaag atgtacaaaa gatgatagac
    56221 aaaaactact ttataaatac ttatattgat aaaagaaata atcagattgt gttaacaaat
    56281 gaagattttg ttccaccaag atatgaagat gtagcatatg aagtcaaaga agaagaaaag
    56341 actgatgaat ccaatgaagt tgatacaatt ataaataaag gaatgaatta tctaacacaa
    56401 ataaaagaag ctaataaaaa tattaaatca gaatcaatgg gcgataaaat tgtacaagta
    56461 gaagatgtta caagtaaaat atttgatgtt gtaaaacatg acccatcaaa acttactcaa
    56521 atacaaaaat ttatggatta ttatcttcca accactttaa aactattaaa ttcatatcat
    56581 acattggaag aacaaggaat tgatagagaa aatataacaa caactatgga aagtattgaa
    56641 aatacaatga atacgattgt agtagctttt gaaaatcaat tggactatct gtttgaagat
    56701 gaagccattg atatttctac agatattact gttttagaga atatgttagt ccaagaagga
    56761 ttaacgagtg gtaaatttta acttcaatag aaaaaatatt ctgttatttt taaacaatta
    56821 attagtcata aagtataaaa tgtgtattat ataagttaat cagtacttta tgaaggaaga
    56881 ggagagaaag atacaatgaa taatttagat gatataccag ttatgccaac tttgacactt
    56941 gacccatttg gagaagaatc aaacactaat gatatagata attctgactt attaatgaaa
    57001 aaggatgaaa aagacccaga agaagaaaaa ctgtctgaat ctgaacgcaa gatggtaaag
    57061 gaatttgcgg aaaaaataga tattacaaat acaaatatga ttttgcaata tggagctggt
    57121 gctcaaaaaa aggtagcaag tttttctgaa acagctttaa agagtgtaaa gacaagagat
    57181 ttaggagaag ttggagatat gcttacaaat ctagttactg atttaaaagc attttcagca
    57241 gatgaaaaag aacaaagtgg ttttttagga atttttaaaa aggcaaataa taaaatttca
    57301 aatttaaaaa ctaagtatga tagtgcagag gtaaatgtgg ataaagtaag caaagagctt
    57361 caaaagcatc aggttaaaat attgaaagat atagcaatgc ttgataagat gtatgaattg
    57421 aacttagctt actcaaaaga gcttactatg tatattatag caggaaaaca aaaattaaag
    57481 gatatgaaag aatatgagat gccaaagttg agagaaaaag ctcgtttatc tggttcaaca
    57541 gaagatgctc aatctgtaaa tgatatggtt tcactttgtg acagatttga aaagaagatt
    57601 catgacttag aattaactag aatggtatcg cttcaaatgg ctcctcagat aagattggtt
    57661 caaaatagta ataatctgat ggcagaaaag attcaatcaa ctatagtaaa taccattcca
    57721 ttatggaaaa atcaaatagt gcttgctctt ggaatttctc acttaaatca agctatgaaa
    57781 gcacagcgtg aagttagtaa tatgacaaat gagcttttat taaagaatgc agaaactttg
    57841 aagatgggaa caatagaaac agcaaaagaa tcagaaagag gaattgtaga tatagacaca
    57901 attaagaaaa ctaatcaatc tctaatatct actattgatg aggtagttaa gatacaacat
    57961 gatggtagaa taaagagaca agaagcagaa gttgaattat caaaaataga aaatgaactt
    58021 aaaagcaagc ttcttgaatt tacagttaaa taaaaattat actaagataa aaagagactg
    58081 tctcaaaatt ggatatgtcc ctgtcaagta gacagactta aaaaaggcta tctttactcg
    58141 gaatgagttc gatattcaat cggactcatt ccgtttttta attgtattct ttcattatta
    58201 taaaaataaa tataatcatt tattagacta atcatttcct ttggatctgt agtatcaatt
    58261 aaatatatta attcagattt aaaatgactg aaaaaacttt ctataggagc attatcccag
    58321 cagttgcccc ttcgggacat tgattgtata ataccattat ccttaagcct tttagagtaa
    58381 gatctacttg tatattgtga accttgatct gtatgtaaaa tacaatcttt agctaaattc
    58441 atatttatta gttgatttac tgtattatta actaatttag tatccatttt tgtacttatc
    58501 tcatatgcca ctatttcacc attaaataaa tctttggcta cattcatata taagaatttt
    58561 ttaccgatag gtatgtatgt tatatccata caaatttttt ctaatggttg attagctcta
    58621 aattcacgat ttaatatatt atcatatatc tcatatgatt taaacttacg tctatatact
    58681 ttctttctaa taatagattt aatacctagt tctttcatca acctatatac tctcttatga
    58741 ttaatagggg tatcaagtat tttatttaaa taagtacaaa ttctttttct accataagtt
    58801 cctctatatt ttttatgtat ttcaattata taatccttaa taattctatc tttgataccc
    58861 ctatcggaag attttttaga ataacttagc catttatagt aaccgcttct tgacacactt
    58921 atcaacttac acatactaga aatactatac ttcctagaca gaagtttaat tgttttaaat
    58981 ttatcgctta ctttgacttg tccaataggg tacttaactt ttttaagaat tcattctcca
    59041 tgcgtaagta cttcaattct tcttcaacag atttaaattt tctattatca ttttctagac
    59101 taatattttt aaatctgccc ctagtttcat catcaaatgc agttttgcct ttatttttat
    59161 aatcttttac ccagttttga acttgtgttt tgcttcttat attcagcatc tcagcaattt
    59221 tgtatgatga gtatccttct tttatatata agtttacagc ttttagctta agttctttgc
    59281 tatatttttt gtgtttttta gacatagaaa aaccccctta gagtatacgc tttttagacc
    59341 tattataata gccttttatt taaatgtcta ctataagggg attatactaa aatagagata
    59401 agtctctttt tcattgttta aatgattaaa gtatatttat attataaatt tctattatct
    59461 tttaacataa catcatgagc tccaccttca actatactag tagaagatac aagtgtaagt
    59521 ttagcatttt tttgaagttc aggaatgcta agtgctccac agttacacat agtagaacga
    59581 actttactta aagaaagagt tacattgtct ttcaaagaac cagcataagg aacataagag
    59641 tcaacacctt cttcaaaaga aagtttctta tctccaccaa ggtcatatct ttgccagttt
    59701 ctagcacgag cagaaccttc tccccaatac tctttcatat aactaccatt tatattaact
    59761 ttgttagttg gactctcatc aaaacgagag aagtatctac caagcattat aaaatctgca
    59821 cccatagcta aagctaaagt tatatgatgg tcataaacga taccaccatc agaacaaatt
    59881 ggaatataaa tacctgtttt ttcaaagtat tcgtccctag cttgagcaac ttcaattata
    59941 gaagtagctt gtccacgtcc tatacctttt tgttcacgag ttatacatat agaaccacca
    60001 ccaataccaa ctttaacgaa gtcagcacca gcttcagcta ggtaaaggaa tccctcacgg
    60061 tcaactacat ttccagctcc taccttaact gtatcaccat atttttcacg aatgaaatca
    60121 agtgttattt tttgccactc agaaaaacct tctgaagaat ctatacataa aacatcagca
    60181 ccagcttcaa ctaaagcagg aacacgttca gcaaagtctc tggtattaat accagctcca
    60241 actacatatc tcttagaaga atctaaaagt tcaagtggat tttctttatg agaagagtaa
    60301 tctttacgga ataccatata cataagatta ccattgtcat caagtacagg aagagaatta
    60361 agtttgtggt cccatataat gttgtttgct tcctttaaag taacatcttt gttagcataa
    60421 actatagatg acataggagt cataaattca ctaactttag tatctaaatc catacgactt
    60481 atacgataat cacgacttgc aacaatacct aataatttac cagttgaagt tccatcttca
    60541 gtaacagcta ctgtagaatg tccagttttt tcttttaagt caagtatgtc ttttaatgtg
    60601 ttatcaggtt taatatttga atcacttaca acaaaaccag ctttgtggga tttaacacgt
    60661 gctaccatag cagcttcatc ttcaatagtt tgagaaccgt atataaatga aataccacct
    60721 tctttagcaa gtgcaatagc cattttgtca tcagaaacag attgcataat agcagaagtc
    60781 aaaggtatat tcatataaat atctgcttcc tcgccctttt taaatttagt aacaggtgtt
    60841 tttaaactta cattagcagg tatacaatca gtagaagaga aacctggtac aagaaggtat
    60901 tcactgaaag tatgtgatgg tgtatcaaaa taaaacgcca ttttttaatc actccttata
    60961 tttttatact ttttataatt gatagtatta attataactt attctttaat tttattaaag
    61021 tattttgtca aatattgaga tttttgaaaa atttaaacta ttttaattga atttgtttaa
    61081 tatatattgc cttatagggt aaagttgtat attaaataat gtttagtgtt taatagtagc
    61141 taatttgaaa ttaatcttta gttattcata taattacatt tgtatagttt atattgataa
    61201 tattgctaga gagtgcataa acctcaaaaa tacagataaa ttaaatctat attagtatat
    61261 ccaaaagtac atttaataaa tttatttaac tgaattatta ttttcatttc tattaaattt
    61321 aaatatttta taaaaatagt attatttaca aaatcatata ctccaaaata ctacataaat
    61381 aaaattaaac aaaaactaaa atgacaaatg tcattatcta aagtgacata gaaacggttt
    61441 cttaaagttg ttactataaa atataaactc tataataaaa gtataacaaa agggaatcat
    61501 atcgatatag aatataattc aagaggaggt aaaattatga gtagttctaa tcaatcgaca
    61561 ataaagacat ctatacagcg agtagggaaa tttttaagtg gtatggtaat gccaaatata
    61621 ggagctttta tagcatgggg tcttataaca gcattattta taccaacagg atggatgcct
    61681 aatgaaaaat tgagtactat aggcgaccca atgataaaat accttttacc actattgata
    61741 gcttatactg gtggtaaagc aatagcagga caaagaggtg gcgtaatagg tgcagcagca
    61801 gctatgggag taattgttgg ggcagatata ccaatgttta tcggagcaat gataatggga
    61861 ccatttgcag gatgggtaat taagaagttc gataaatttg tagatggaaa gataccaaca
    61921 ggatttgaaa tgttagtaaa taacttttca ataggtataa taggtatgct tcttgcaata
    61981 ctaggatttt atgcaattgg accagcaata gtagcaggga cagctcttat agaatctgga
    62041 gttcaattta tagttagcaa aagtttattg cctttagttt cagtatttat agaacctgga
    62101 aaagtattat tcttaaacaa tgcaataaat catggtatat tagggcctat aggtatagct
    62161 gaggcaaaag aagcaggtaa atctataatg ttcttactag aaagtaaccc tggaccaggt
    62221 ttaggagttc tattagcata ttggatgttt agtagaggaa gtgtaaaaca atcagcacca
    62281 ggagctgtaa taatacattt ctttggtggt atccatgaaa tttacttccc atatatttta
    62341 atgaatccag ttttaatatt ggctacaatg gcaggtggag cagcaggaat attgactttt
    62401 tcaatattag gagctgggct tgtagcagca ccatcaccag gaagtatatt tgcacttatg
    62461 gcactagctc caaagggagg attacttcca gtattagcag gggttgcagt ggcaacagtt
    62521 gtatcattct tagtggcagc accatttgtt aagagagctt cagcaaatga aagtgaagaa
    62581 gacagtactt ctttagaaga agctaaagca aaaatgagtg atatgaaatc tgcaagtaag
    62641 aactctgaga aaaatattga gaaaaaacag cttgaagtaa atgagattaa gaagattgta
    62701 tttgcatgtg atgcaggaat gggttcgagt gcaatgggag cttctagatt taaaaataga
    62761 ataaaaaact tagatttaga tatagaaatt acaaattcat ctgttgataa tcttccagat
    62821 gatacacaaa tagtagtaac tcacaataca ttagttgaaa gagttgctaa gaacaattca
    62881 agtgttgaga tagtttcaat aaacaatttt ttaaatgacc caaatttaga tacattattt
    62941 aaaagattag aatctaaata aaaataaaaa gtaccactaa ttaggagtgg ataatttgaa
    63001 aaaaaagaag attacatcta ggcaaaaaaa gataatacta atgatagtag aaaattcaaa
    63061 gaaaaacatt ccaataacta tttctgagat tgcagggacg ttagagttaa gttcaagaac
    63121 tgtacttaga gatatgtctg gaattgaaaa atggtttgat gaaaatgatt ttaactttgt
    63181 aaaaaaacca ggagtaggat tgattttaga ggaaaatata gaaaatcaaa actttataat
    63241 tgagttgtta gaagaagaaa aaatagaaaa agaatacagc aaggaagaaa gaaatttaat
    63301 tatattatca aagctactag tttctaacga gccagtaaaa tcttattatt ttgcaaaaat
    63361 attaaaggta tctgaagggg tactgaataa tgatttttca ttagcaagta aatggttgga
    63421 aagatttgat attgagcttg ttagaaaacc agggcttggt gtctacctaa aaggtcaaga
    63481 aaaaagcttt agagaggcat atgtaaatct tatatacgat tcattcaatg aaaaagaaat
    63541 actagatatg gtcagaaata taagtgaaaa tatacaaaca gataaagcaa tagaaatttt
    63601 aagtgaaaat agacttttaa atttaatgga taggtgcata ataataaaag ttgaagctac
    63661 attaacaaag aagctttcag atttagatgt aaatttagct gatagtgcat atatagggct
    63721 tgtagttcat atttcattag ccttacagag gataaaaaat ggtgaaaata taactatgga
    63781 taaagagttt ctaaaagaat tatctataac agaagagttt aaattagcta aagaaatcgt
    63841 aaaaggtatg gaaacagatt ttaacatgga tataccagta gatgaggttg gatatataac
    63901 tatgcatata agaggtgcaa agcaaaggtc atcttcaaat cataaggctt taaacttgga
    63961 tgatatagaa ataatggaaa ttacaaataa gatgatagat ttggctgaag atgaatttaa
    64021 aataagttta aaaaatgacg agaggttatt taaagaccta gcaaatcact taggaccttc
    64081 tataaataga ttgaatatgg gattagaaat aagaaatcct cttttagatg aaataaaaag
    64141 caagtattca tatgcctatg atggagttga aaaaatttct agaattataa aagataaact
    64201 aaatataaat tcaatacctg aatcagaaat aggatatatt gcaatgcact ttgcatcagc
    64261 catagaaaaa aatcttatga tgaatactaa tataaatatt gttgtggcat gtcccactgg
    64321 aataggtact tcaagattct tatcaactaa gattgaaaat aaatttccta atttaaatat
    64381 acttgaaacc atatcagcta taaacataga tgaagagtat ttaaagggaa aagatgttga
    64441 tttaatagtg tctacagttg agttaaatac aagtttaaat tatatatgtg taggtccatt
    64501 tatgagttta gatgatgaac agataatcaa ggaaaaaata aaatctatag ctcaaaataa
    64561 attaattaat ttaaatacaa aaaatgatac taaaagtaag aataaagtat atgaacagat
    64621 aacagaaagt atgaatatag gaaaagatat tcttcaattt ttagaggaaa ttagatttga
    64681 aaaatttgaa agtaaagatt taagtgagct tattgaagac tcatcaaaaa tatttgcaaa
    64741 atctagtgaa gatataatgt ctataaaaga atcgttaaaa gaaagattaa aaatctcaat
    64801 tccatatata gaagaatcaa aaattctatt attacattgt atgagtgaaa gaatagatat
    64861 tatgaagtta tcaataataa aactggagaa tcgaatcgtg ctagattcaa atgaagaaat
    64921 cgacaatgta gtttttatgt tacttcctaa aaattcacca agttatcaaa gacaaataat
    64981 gagtgaaata agtggttcat taatagacaa tataattttt actaataaga taaataaatt
    65041 ctctatagaa gagatgacat tagaggtaaa agatatagtt tttaattttt atacaaacag
    65101 attaaaagca tttatagatg aataaaatta atattaaaaa ggaaggttga tactatgagt
    65161 aaagtattga atgagaataa tatattttta gggttagata gtgtttcaaa ggaagaagct
    65221 ataactttag caggaagaaa attagttgaa aatggatatg taaaagaaga atatatacca
    65281 gcaatgctag aaagagaaaa agtaatgact acatatatgg gaatgggagt tgctattcca
    65341 catggtgtaa atgaagcaaa aaaagaaata ttatcttctg gaatagttat actacaattc
    65401 cctaatggta tagattttga tggagaaaaa gcatacttat taataggaat agctggtgtt
    65461 ggagatgaac atttagaaat actatctaat atagcagtag ttttagatga tgacttaaca
    65521 gaaagactaa aaaattcaaa tgacaaacaa gcttttatgg aagcttttgc caaataatct
    65581 taggagggat ttaaaatgaa aaaggcaatc cagtttggag caggaaatat tggaagaggt
    65641 tttattggag gcttgttagt taagtcgggt tatcatgtag tatttgctga tgtaaatgag
    65701 gagatattaa actcaataaa taaagataaa aagtatacta tacacataag agatgtagaa
    65761 tgtatagatg aagtaattga taatataagt gcggtttcat ctataaaaga agaaataata
    65821 gatgagattg tacaggctga aataataact acagcagttg gacctttagt tttgactaaa
    65881 atagcctcta caattgcaaa aggtataaag gctagaaaag aaaagggttt aacaagtaat
    65941 ctaaatataa tagcctgtga aaatgcaata tacgcaagtt cttctttaaa agaagaggta
    66001 cttaagtatt taaataagga agaagtagaa tatttagaga tatatgttgg ttttccaaac
    66061 tgttcagttg atagaatagt tcctcctggt aaaaatgaaa atcctcttga tgtaacagtt
    66121 gaaaattttt atgagtggaa tgttgaaaaa caaggattta aaggggaaat accaactata
    66181 gttggaatga atttagctga caaccttatg gcttatatag agcgtaaatt gtttacactg
    66241 aatacaggtc atgctataac agcttatata ggatatttaa aaggatataa gactatagaa
    66301 gagagtataa aagataaatt tatctgtgat atagtcaaaa gtgcaatggt agaaagtgga
    66361 gaaggattga ttaaaaaata caattttgac tcagaagcgc actataaata tattgataaa
    66421 attttaaata gatttaaaaa tccatatctt aatgatgatg tattaagagt tggaagggaa
    66481 ccattaagaa aactaagtga taaagataga ttgattaaac ctttaatgac agcaaaatca
    66541 tatggattat cagttgacaa tttgattctt ggaataggtg cagcgcttca ttataataat
    66601 agtgaagata ctcaaagtgt agaattacaa gagttgataa agtctaatgg tgtaaaaaaa
    66661 gctgttgcta aaatagctaa tataagcaat gacgaagaac ttttaaataa tatcgaaaaa
    66721 agttatatat ttatgaaaaa tttataaatt tacttgaaaa aaagtagttc tgataaagta
    66781 actataatat attattctac acagtttgaa ttatttgttg aataatagag aattataata
    66841 tataattaaa aggaataaat taatatattt acctgtatat gtttgataat atggttcaaa
    66901 tgtttctact aagctaccat taatagcttg actacaggag tgaagaagat atagtttata
    66961 cttattttaa attatatatt aagttaatta ctttgaattt taagctcctg tctatgatat
    67021 agacaggagc ttttttagta ttttaatata aaatacttac aagaatagat agcaaaatta
    67081 gaacaaatat aattttttta ttaatataac tttagaaagg gctaggtgga agttcaatga
    67141 aggctttaca agaaaagata ttgagagaag gcagtgtttc aggaaatgat atactaaaag
    67201 ttgatagttt tttaaaccat caaattgatg tagctttttt aaatgaaata ggaagagaat
    67261 ttaaagagag atttaaagaa gaaaaggtgg ataagatatt tacaatagag gcttcaggaa
    67321 tagctatagc atcaattgtt tcacagtatt ttgataatgc acctgtagta tttgcaaaaa
    67381 aatcagaatc taaaaatttg gataaagatg tatatgagac taatgtatat tcatttacta
    67441 aggcaagaga atattcagtt aaagtttcta aaaagtacat aaacaaaggt gaaaatatat
    67501 tgatagtgga tgattttttg gcaaatggaa gagctgctct tggacttaaa gatttaattg
    67561 agcaagcaga agctaattta gttggagtag gaattgtcat tgaaaaagga tttcaagctg
    67621 gaggagcact tttaaaggct aatgatgtaa gattagagtc tttggcggta gttgaatcta
    67681 tagataatgg aactgtaaaa tttaggtaat ttatgatatt atatacttgt gtttagcaca
    67741 tattttaact atgtaattat ggaggatttt ttatgatatt ttttatagac acagccaata
    67801 ttgaagaaat aaaagaagca aatgatttag gtgtaatatg tggtgtaact actaatccat
    67861 ctctaatagc taaagaaggt agagatttta tagaggtagt taaagaaata agtgaaatag
    67921 tagatggacc aataagtgca gaagtaataa gtttagagca tgaaggtatg atagaggaag
    67981 cagaaaaatt atctaagata cataaaaata tagttataaa gatacctatg acagcagaag
    68041 gtctaaaagc ggtgaaagta ctatcaagta aaggtataaa aactaatgta acacttatat
    68101 tctctgctgg acaagctctt ttagctgcta gagctggagc tacatatgta agtccttttg
    68161 ttggtagatt ggatgatata tcacaaaatg gtcttgattt aattgaagaa atcgttgata
    68221 tatttagtgt aaatagtatt gaggctcaaa taatagttgc tagtgttaga aatccaatac
    68281 atgttttaca agctgctaga atgggagcag atatagcaac agttcctctt aaagttataa
    68341 accaaatgat taagcatcct ttgacagaca aaggaataga tagctttatg aaggattggg
    68401 aaggtgcttc tttaaaatta taattataaa ctacgcttta taagtatatt aaagaggtta
    68461 ttatggaaat tctaagtaat aaggctaggc tattttgcct agtcttattt tggtgtataa
    68521 tatattgaaa catattattg aaatagatta attttttaag tgaggaggcg aaaaatggat
    68581 aaaatattaa gagagataca aagagaagat aaaaaaaatc catatactga ccaagaactt
    68641 gctgaaatgt taaatgtagc taggtctgaa gtgatatcag tgaggaaaaa aaataatatt
    68701 ttagattcga gagaaagaag aaaaaaaata ttaataaaag atatatcaaa aattgtaagt
    68761 gaaaatcctc aaatgtctga aagaaaaata actgagatat taatagagaa tggatataat
    68821 atatcgagaa gtgcagtttc aaaattatta aaagaagaaa atttaaatca gtcaaagatt
    68881 gggattaaag ataaagagcc agcatcatca ggaaagtatg tgaaggtgag taaagttgta
    68941 gaagaagatg gatttgaaga attgataggt ataaagggaa gtttgaaaga aaaggtaaat
    69001 ctagctaagt cagcaataat gtatcctcct aatggccttc atactataat atatggagaa
    69061 acaggggtag gtaaaagtga attagctaca tgtatgtata aatatgctat aaaaaacaac
    69121 atcaaagaag agaacagccc atttatagtg tttaactgtg cagactatgc agaaaatcct
    69181 aatctattga tagctcaact ctttggggta gtaaaaggtg catatacagg agctgatgca
    69241 aatagagaag gtcttgtaga acaagctaat aatggaatat tgtttttaga tgaaattcat
    69301 agattgcctg ctgctgggca agaaatctta ttttcattaa tagatagagg agaatttaga
    69361 aggttaggag aaagtagttc taatagaaag gcaaatgttc tcataataag tgctacaaca
    69421 gaaaacccag attctaattt acttcaaaca tttagaagac gtataccaat ggtaataaat
    69481 ttacctaata tgagtgaaag accaaaatct gaaagatatg aaataataat aaagtttttt
    69541 gaaagagaag caaagcgagt aaacaagaat tttataataa ctaaagaagt tatgtgtgca
    69601 cttatgaatt ataagtgtac tggaaatata ggtcagttaa agagtgatat acaagtaact
    69661 tgtgctagag cttttagtaa atcaatattt tctagcgata aggtaattat agatttagat
    69721 agtttaaggg attatataaa aagtggatat tatgattgta attgtaaaaa tgaaaagtat
    69781 tctgagtttt cagttgagga tatatatata gatatcagtg aattggtgag tggaaaaaat
    69841 agaattttat ctgataatga gataagcgag atatataatt atgcagaaaa agagcttaag
    69901 gttttggaaa gtaagtgttt ttcagaagaa gagttaaaaa atgcatttat agaaaagtta
    69961 gataagaagt ttaatgctat taaaaacaat aaaaatttat ctgatagaag aagtcgaata
    70021 gactggggag gacaattaaa agagtctaca ttggagataa tggataaggt aattgtattt
    70081 attaaggagc agtttaagca tgtaaatcaa ggattgtact tggctctagc aattcacatt
    70141 gagcatgcta taggtaggat aaaagatgga aaaactataa taaatccgag tttagataaa
    70201 ataaaagcat caatgccaat ggaatatgaa ttgtcaagat atataatggg tatagtggaa
    70261 gatttgacac aagtaacatt tccagaagat gaacttggat atttggctta ttatataaat
    70321 aaattttgtt ataatgagga aagtataaaa gataaagtta aagtagtaat agttacgcat
    70381 ggtaaagttg gaattgaaat gtctaaagtt gtaaatcata ttttaggtat agaatgtaca
    70441 ctaggtatag aaatagcact tacagattca ccatcagagg ggatagagca tgtattagaa
    70501 gagcttcaaa agatagaagc tagaaaaggt attctagttc taattgatat gggttctttg
    70561 gtaattcttg gtgatgaggt tgaaaaaaga cttggaatta gatgtaaaac tgtaaacaga
    70621 gtagatacgt tattggcaat ggaagcagga aaacttgcaa ccattgaagg aaaaagttta
    70681 gatggtataa tagcagattt aaagaaaaat aagaattatg ccatgataaa tacaaataaa
    70741 tttagttaca gaaaaaacga gtatggaaag aaaaatgtaa tcattacttt atgtttgagt
    70801 ggtgtaggta cagctttaaa tttaaaagag catatagaaa aacaaattaa ggaatatgac
    70861 actttaattg aggtaaagcc agttgctttt ttaaataata atttagaaga agagttaaat
    70921 gatattgaag ctgaatataa tattattgct atctgtggaa ctatcgatat agattataaa
    70981 aacgtacctt ttatttctta taatgaggta cttggtaaaa atggtattaa taaagtatta
    71041 gagcatttaa acagtaaaca accagtttta aatattgaaa accagttgaa taatttaata
    71101 catgaagatt tgattttata caattttgaa ggaatttcaa aggagtatat aattgatact
    71161 cttgtttcaa agcttgaaga aggtggatat gttgactcaa agtatatatt aagtgtatat
    71221 aaaagagaag caatgggaag tgttgtaatg gcctctaagg tagccgtgcc acatggactt
    71281 ccagaaaacg ttataaagcc tgcaatagca atcgcaaggt tgaataagcc tatagtgtgg
    71341 gacaataaat ttatggtgga tttggtagta ctactggcac ttaaagaaaa taataagaaa
    71401 gaaatacgaa gcttattttc aaagattaat gaccaacata ctttagaagt tttattaaat
    71461 actgaagata aaaatgaaat aaaagaactt ttaagctaat tattagtaca gagaagaaag
    71521 acaaaaaatt tgctttagta taaaatttaa aactacttaa ttgctaagta gttaattact
    71581 cgatataagg ctagttctat gaaatttatt tatatgattt tatagaatta gcttttttct
    71641 tggtaaataa aatatatgaa tttatttatg caaaaagtaa attt
//
LOCUS       DAMJVG010000011        67157 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.011, whole genome shotgun sequence.
ACCESSION   DAMJVG010000011 DAMJVG010000000
VERSION     DAMJVG010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 67157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 67157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..67157
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.011"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            628..1956
                     /locus_tag="PC512_000815"
     CDS             628..1956
                     /locus_tag="PC512_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDF2440585.1"
                     /translation="MGSNELKKTLGVSAALSTVVGSVIGAGVFFKPQAVYTLTGGAPG
                     LGILAWLIAGIITITAGLTAAEVSVAIPKTGGMMVYIKEIYGEKLGFLTGWMQIVLFY
                     PGMMAALGVIFGEQASALIGSPSLLLPIAIGIIVIVAGLNMLGSKTGGVIQTVSTICK
                     LIPLILIMVVGFIKGGGNNPILTPMVGEGLSLGSVLGQVLIAILFAFDGWMNVGTLAG
                     EMKNPGKDLPKAIIGGLSVVMAVYFIINLAYLWVLPANELANYASPASAVAEVIFGSM
                     GGKIISVGILISVFGALNGFLLTGSRVAYTLATDKTLPKYGIFSKLNSAQVPANAIAL
                     VSVIASIYALSGQFNLLTDLAVFATWIFYVLTFIGVMKLRKTHPNIPREYKVPLYPIV
                     PIIAIASGIFVVVNQLCFAGMKTTMISIGGLVITAIGLPVYAYMTRGVKR"
     gene            2709..3542
                     /locus_tag="PC512_000816"
     CDS             2709..3542
                     /locus_tag="PC512_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase"
                     /protein_id="HDF2440586.1"
                     /translation="MRNKKKKINRKKLYLLLSAIVVCLAFIVVGVRVSSLNMKENEIS
                     RNAKLSSSTITDIVSNTSIEVSKGPSKSSGKIAYITIDDGPSKFTDEMIKTLNKYNVK
                     ATFFMIDGNMKEYPQQVKNIIKNGNTAGFHSVSHDIHKLYVTSTSAKEEFDTNDQTFY
                     KITGKHSKVIRIPYGSKPYTPQASYQALVDAGYKIWDWDLDTEDWRSNSSQIVQNVKN
                     HIKNRKGEDKDQLVVLMHEKKQSAEALDSVLKFLSDEGYEFAPVDQNQIPKNYWLRNL
                     E"
     gene            3635..4567
                     /locus_tag="PC512_000817"
     CDS             3635..4567
                     /locus_tag="PC512_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDF2440587.1"
                     /translation="MVGILSLMMVGCNKSLAKVNDVEITKEQYKKTKAVLSATNNYIN
                     GQSLDELEKTLDKKGRNKLENVIISFMVDNELLYQEAKDKGLTPSKSEVDSKYQELED
                     KMNLNTSYKEKMDKAGVDKDYLKQEISRDLAIDKNKKAFEDRINISDNDMEAYYTSHK
                     KDFNVEEVSASQILISTLDKNKKEVSKDKKEALKKKADNILTKIKNGESFESLAKKYS
                     DDKATGKNGGQLGYFTKDDKNAEFTKEVFKLKKNEVSNVFETSYGYHIVKVTDKRERQ
                     KSFNECQSLIRESILNEKYIEHIKKLNEDAKIDR"
     gene            4619..5101
                     /locus_tag="PC512_000818"
     CDS             4619..5101
                     /locus_tag="PC512_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF2440588.1"
                     /translation="MFKSLKRTKVEKYIIDNKDSFYRIAYSYTKNEEDALDVVQEAMY
                     KALYSVENIKEVNYIKTWFYKILVRTSIDFIRKNRKYNNMTDIDLIDETGEYDKYTDL
                     DLRRALEELPIEYKSIIILRFFEDLKIEEVAIILDENVNTVKTRLYTALKKLKLKIEE
                     "
     gene            5113..5982
                     /locus_tag="PC512_000819"
     CDS             5113..5982
                     /locus_tag="PC512_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HDF2440589.1"
                     /translation="MTSKERLNKLKDEYHKIPIPKKLDTIINHEKIENIYREKNKKVN
                     RLRFKVAIAFACIFTVLVNISPVFADNFSKIPVIGAIVEVITIKNYSLKSENYEAEID
                     IPKIRGLKDKNLEQRLNSSFMEDGKRLYHQFQERMEKIQSSKNKGYKSLSLSYSVKNN
                     SKKFLSIEMTKNEIEASSYVSKVHYTIDKKRQIVLTLPMLFKDDKYIKVISDNIKEQM
                     REQMKKDSTKSYFIDQKKDLPVEDFKTINKYQDFYFNKNEDLVICFDEYEVAPGYMGA
                     VEFVIPYKVIKDL"
     gene            6025..6780
                     /locus_tag="PC512_000820"
     CDS             6025..6780
                     /locus_tag="PC512_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HDF2440590.1"
                     /translation="MTTYKKLKKSIFKIAIFSICLLVSLVDTNPIFAGSSFNETSNSD
                     TIKVLNAKSINFKQDNYEVNVSIPKIKGLKDKTLENKLNNEFLQDGKKIYSEFQNKMK
                     KENNKGHRYLNVIHNVKNNSKDFLSIEMTKEEIEASSSITKKHYTVDKNRGILLNLPI
                     FFKDSRYIRAISDNIKEQMRNQIKKDDTKSYFIDQDKDSPVKDFESINKYQDFYFNKN
                     GNLVISFDEYEVAPGYMGAVEFVIPNKVIKRLR"
     gene            6822..7643
                     /locus_tag="PC512_000821"
     CDS             6822..7643
                     /locus_tag="PC512_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine dehydrogenase accessory factor"
                     /protein_id="HDF2440591.1"
                     /translation="MNIYEQAIRLIENNEDFAFATITSHSGSTPRETGAMMIVKNDST
                     IFGSVGGGSVEAECIKHAINVIKNRESMLYKFTLNKSDVAKLGMICGGTGEIQIDFID
                     SKLKSNIEKFNKRLKENTSKAYIFGAGHISRDVAVILSLLEFRTVVIDDREEFANHER
                     FPESEVVVLDSFENIPDFPTDENSYIIILTRGHLYDSSALEWALKREAGYIGMIGSRT
                     KIGLTYEKLMKKGFKKEELSKVHAPIGIKLNAQTPAEIAVCIAAELINCRANKEK"
     gene            7648..8409
                     /locus_tag="PC512_000822"
     CDS             7648..8409
                     /locus_tag="PC512_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M48 family metallopeptidase"
                     /protein_id="HDF2440592.1"
                     /translation="MNTGSKDIDTLKVNFRGIEIKAVLVYKNRKNISIKIDPFGKITV
                     MSPPKISKKIIKDIIIEKGDWILKKSEKCKGREEVYKQRMFITGEKFLYLGEEYHLVI
                     KELLRDSVKKSNCRITINEYQIVVQTNDTSTDFIKKSLKSWYKMESERIVLERIDFLK
                     LNCEIMKQLVPASVKVKEQNKRWGSCTAQKNIYINSKISMARLDVIDYVIIHEFSHLA
                     HMNHSKKFYDLVKSIMPDYKDKENWLKINGYKIII"
     misc_binding    8570..8827
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            8940..9179
                     /locus_tag="PC512_000823"
     CDS             8940..9179
                     /locus_tag="PC512_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HDF2440593.1"
                     /translation="MENTVYAKLNQGIDSFLRVAMTLRRREVDIQSISMTVDNMNNSG
                     IKLIVNEEKTSLDSVLNHMKKLHDIREITVERMRH"
     gene            9483..10478
                     /gene="ilvC"
                     /locus_tag="PC512_000824"
     CDS             9483..10478
                     /gene="ilvC"
                     /locus_tag="PC512_000824"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HDF2440594.1"
                     /translation="MKMARMYYEKDVDLEVLKNKKVAVLGYGSQGHAHAQNLRDNGVH
                     VVIGLYDGSKSAQKAKEDGFEVKSVAEATKESDLTMMLMPDEKQKKVYEESVKDNLKE
                     GQTLAFAHGFNIHYNQVQPPEFVDVVMVAPKGPGHLVRNVFTKGSGVPALFAVYQDYT
                     KKATETVLAYAKGIGATRAGVLETTFKEETETDLFGEQSVLCGGISELIKLGYKTLVD
                     AGYQKEVAYFECLHEMKLIVDLIYEGGFERMRYSISDTAEYGDYVSGKRVITDAAKQG
                     MQNVLEDIQNGKFAKAWIKENEEGRENFLKTREEEYNTEIAEVGRNLRSMMSFLK"
     gene            10531..12219
                     /gene="ilvB"
                     /locus_tag="PC512_000825"
     CDS             10531..12219
                     /gene="ilvB"
                     /locus_tag="PC512_000825"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biosynthetic-type acetolactate synthase large
                     subunit"
                     /protein_id="HDF2440595.1"
                     /translation="MSGAKVILECLKKEGIDTIFGYPGGAVIPLYDALYDYSDDFKHI
                     RTSHEQGLVHAADGYARSTNTVGVCFTTSGPGATNAITGIATAFMDSSPMVVISGQVP
                     TSLLGKDSFQEIDITGATLSMTKHNYLVRNTKELVPTIKEAFRVANSGRKGPVLVDVP
                     KDLFLAEMDFSGEDYDLCQIDDYMDYKSDFDLDDETNIKLLNEAIDIIKESKKPIIYA
                     GGGVKSSDSEEILEKFATKIDTPVLNTLMGLGNIDRKNELSLGMVGMHGSRESNLALS
                     NSDLVIAIGARFSDRVISKSSEFAKNAKIIHIDIDPSEISKNIESNVSLVGDVKLVLS
                     LLIERVESKNNSNWKEEIKRFRKSEGVQTYEFHPQNILKKINEKYETLKKPTVVVTDV
                     GQHQMWAAKYWNFKGNKSFITSAGLGTMGFGLGAAIGTKVGNVDKNVVLVTGDGSFRM
                     NCNELATVANYNVPMLILLLNNRTLGMVRQWQKLFSNQRYSQTDINENVDYVKLVNAY
                     NIDGYKVSSMEELGKALDMIDFNKPVFLQCDIDKDYDVYPIVAPNDALENLICN"
     gene            12430..13107
                     /locus_tag="PC512_000826"
     CDS             12430..13107
                     /locus_tag="PC512_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HDF2440596.1"
                     /translation="MFKHDKALLKEVKVERPNPQYAVLMQEQLGGANGELKAAMQYLS
                     QSFRIKDPQIKDLFLDIAAEELSHMEMVAQTINLLNGHDVDYNSVNTGEIETHVLTGL
                     SPVLINSSGAPWTANYVTVTGDLVADLLSNIASEQRAKVVYEYLYRQIDDKYVKETID
                     FLLNREEAHNALFRDALNKVKDTGSNRDFGVTEDSKLYFDLSTPGPNHDTKIDINPPS
                     FEKPLKK"
     gene            13281..15317
                     /locus_tag="PC512_000827"
     CDS             13281..15317
                     /locus_tag="PC512_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin domain-containing protein"
                     /protein_id="HDF2440597.1"
                     /translation="MDSNRKPNNLINEKSPYLLQHAYNPINWYSWNDEAFKKAKEEDK
                     PIFLSVGYSTCHWCHVMEKESFEDEEVAEIMNRNFVAIKVDKEERPDVDSVYMTVCQA
                     MTGSGGWPMTIIMTPDKKPFFAGTYFPKYSRYNRPGVIDLLENVSEKWNTSRDILIKS
                     GDEIIEALKDDFGVKNTEGDLSKEMLSSSVRVFKAIYDEKYGGFGNAPKFPSPQNLMF
                     LMKYYSIEKDKDVLKMVEKTLDGMYRGGLFDHIGFGFSRYSTDKKWLAPHFEKMLYDN
                     AMLTIAFLDAYKITKKELYKEIAIKTIDYVVREMKDKEGGFYSAQDADSEGEEGKFYT
                     FNPLEIIEVLGEEDGIFFNNYFDITSSGNFEGKSIPNLIKNKEYERHNEKIADLSKKV
                     FEYRKERTSLHKDDKILTSWNALMIVALTKAYSTLKNDIYLEYSNKCLNFINNNLVNE
                     SGRLLARYRDGSSDYLAYLDDYAFLIWAYIELYESTFNMKYLEKALNLNESCINLFWD
                     YEKSGFYIYGKDSENLIARPKDLYDGAIPSGNSVQLYNLIRLAKITGDNRLEEMSYKQ
                     LKLYVDNVKSSPTGYSFYMLSLMFELYSTKEIICIFKEDSDLIAFKELISENFIPNAT
                     FLAKKYNEENTIIGFLNNYILKDDKTSYYVCQSNSCSQPINDLQKLKDMILGVE"
     gene            complement(15508..16074)
                     /locus_tag="PC512_000828"
     CDS             complement(15508..16074)
                     /locus_tag="PC512_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2440598.1"
                     /translation="MDYSNELKELFLMNQTYATLFTLTNKIQIEGDKYFGILTSRQYM
                     TILSILHLPEEETTLNNIARKMGTSKQNINRLVANLEKNGYVDVIPSPHDKRAINVKV
                     TDLGKKVMVTCSRTGINFMADVFHEFTKDELETLWSLLKKMYRFNGEEQDGFEEDANF
                     MEYEEIDKIKSEALEEFAKRRNRVNKKD"
     gene            16362..17297
                     /locus_tag="PC512_000829"
     CDS             16362..17297
                     /locus_tag="PC512_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2440599.1"
                     /translation="MKCTNFTFKGEEGLDIYTYKWEDENIKKPKAVIQIAHGMAETAQ
                     RYETFAKVLTKNGYIVYINDHRGHGKTAKIIENVGHLAEKEGFRCLVEDMYTLTNIIK
                     KENEDLPIYLFGHSMGSFASQRYIMDYSNNLSGLILCGSNGKQGIILNLAHLIINREI
                     KKYGRRSKSNKINNLIFGGEIIRRNEKTKFDWLSRDKEQVEKYINDPFCGVVCSCGFF
                     YDLVQGLKEIEDKENLKKVPLDIPIYIISGDKDPIGKNGKGVLRLRDRYIKLGVKDVT
                     CKLYKDGRHELLNEINREEVFEDIICWLNNKIEIL"
     gene            17762..18976
                     /locus_tag="PC512_000830"
     CDS             17762..18976
                     /locus_tag="PC512_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2440600.1"
                     /translation="MQIKIGKVIQCLRKERNLTQEQLAKFIGVSTPAVSKWESGNSYP
                     DIELLPLLADFFNVSIDKLLNYKIDLSEEEVMKIYKELESGFARIEIDLSTEEPKEEF
                     RQDLESVKKLSNMYIEKYPKSYLLKLRICSLYQMYSYKFGKSELNDRVKETMNILEDI
                     VRNTDDIQIKETALIILSNAYCMLEDYEKAELYLNMIHKSIGDTSVNLAMIYLKQNRL
                     EEAEILLQNKLFSNVFNISMDCKGIINVYKNQYKELKKKLENRNFNKNAIEREMEYIK
                     NKLLGYANLSLEIKKMLSEDKGAFFSMYMDYMELSLIFLFFNMKEEAKKALYSLKEIL
                     EKYPIHESLDVSQMRFFDKVESKNLYTFNIYTNLLIVLNDDSYNELREEPIFKDVIEK
                     ILDMEKMLKNKE"
     gene            complement(19396..19917)
                     /locus_tag="PC512_000831"
     CDS             complement(19396..19917)
                     /locus_tag="PC512_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2440601.1"
                     /translation="MKFKRLRTSENKLCYKAMELYKISFPFHEQRKSSLQEEILKNKE
                     YQFNLIYDKNQFVGIILCWETDDFIYVEHFCIFPEMRNNRYGQRALELLNKKGKTIIL
                     EIDLPIDEISIYRKAFYERVKYKTNNYEHIHPPYHEKFNGHNLIVMSYPEKLSKMEYD
                     KFNHYLRNNVMSF"
     gene            20273..21070
                     /locus_tag="PC512_000832"
     CDS             20273..21070
                     /locus_tag="PC512_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HDF2440602.1"
                     /translation="MEKREKRIIISSLLSVSILMGLVSIYSILNKEDIILTVKGQEQK
                     VSSFKKTVEELLDEQGIKYNSEDKINPSLDTELKDDMKIKVVKVTKSKKEEIEKIPFD
                     TKHVNDSNLLKGKSKVYQEGQEGEKKLVYNLTYHDGKLVKKVLSKEVISKEPTTKIIK
                     YGTKEKVLIASRGANIRGGKHMKVVATAYAGDTITSTGTTPRWGVIAVDPRVIPYGTK
                     VYIPKLGMTFVAEDCGGAIKGNRIDIFMNSEGKASNWGRKSIDIYLH"
     gene            21180..21770
                     /locus_tag="PC512_000833"
     CDS             21180..21770
                     /locus_tag="PC512_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HDF2440603.1"
                     /translation="MKIVCLGDSLTYGFGVSRSNSWTNIVNKETRLEIVNKGINGDTT
                     SGMLARFNEDVVKNSPDIVFIMGGTNDFIAGAGNEIINSNIMAMVHQSYSKNIIPIIG
                     IPLKPDIPNVREDWSCFTDFNIVSQNLESYSYWIKKFCMTFNTNFVDFYSEYNKNMEL
                     EGYKKLYFDGLHPTKEGHRIMADIFINSINKYIEEL"
     gene            21836..23533
                     /locus_tag="PC512_000834"
     CDS             21836..23533
                     /locus_tag="PC512_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HDF2440604.1"
                     /translation="MDYTKTYEEWIKGSYFDEDTKLELENIKNNEKEIEDRFYKDLEF
                     GTAGLRGIIEAGTNRINKYTVRRATFGLANYILENTTKEETSRGVVIAHDNRHKSRQF
                     CIESANTLAACGIKAYIFDSLRTTPELSFAVRSLNAIAGIVITASHNPPEYNGYKVYW
                     EDGAQVMPEIANAITEKVNSIHDYSTIPTLTEANKNLVVLLDESQDTKFIEAVKSQII
                     RKDLVKNVGKSFKIVYTPLCGTGNVPIRRALKEVGFENIIVVPEEENPDPNFAGLDYP
                     NPEEKKALNRGILLAKEKGADLVIATDPDCDRVGVAVKTTTGEYALLTGNQIGGMLTH
                     YIIEGLKENNKLKENPTIIKTIVTSEFGADIAKANNVDVLNVLTGFKFIGEKIKLFEQ
                     NKNRSYVFGYEESYGYLVGTHARDKDGVVSSLLISEMAAFYYSKGMSLYDGLIELYKK
                     YGFFKEQTISLTLKGIEGVEKIKEIISYFRENQIDYINSIKVVDKKDYKNGIDNLPKS
                     DVLKYFLEDESWVAIRPSGTEPKLKFYIAVKGASDIEADKKIQGLKKYIDDMVEKLK"
     gene            23747..24586
                     /locus_tag="PC512_000835"
     CDS             23747..24586
                     /locus_tag="PC512_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HDF2440605.1"
                     /translation="MFGIDKKLIEYIIAKSNYSELSSKSAEVSFFLMLSIFPFLIFTI
                     SSIAYIPILHLNKYIALFRNMMPEGAFAVLSSIIVSAIDNRNLKFLAVSFVLTMWTFS
                     RAVKALIKGMNRAYKVKETRSFFKILSISFLFTIMLLVLIFLSMIFLVYGEKIGYFIF
                     NLVGLDEIFIKIWDILRYTVGIITIIVIFTLLYKYTPNKKLTIKESAPGAIFATFAWF
                     LVSFLYSYYTNYYANYEVIYGSIAEIIVLMTWMYFSSWSIVIGYEVNSRLYFRKIRHE
                     MLK"
     gene            25103..26959
                     /locus_tag="PC512_000836"
     CDS             25103..26959
                     /locus_tag="PC512_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HDF2440606.1"
                     /translation="MDTHNKYVNFIKNIPVPFLYCRIVKRQEDIEYRVEYISKGMGKV
                     LQLEEGICDKNILDVLPVFKSKKYFKELFSNEVDCIKRYIPTLKNWINIKKQIIGDSY
                     IILYFGKIVFDYRQIIDSFDKKEKVAYIKDEEGIYIDCSENLIPILNNNIKTTKDIFG
                     KNDIEVWGENTGKLFRDDYREGVSSKKRFLQNLFEYEETFFMVEKYFLYDEDELLGTI
                     GIVDNIIYSGYSNRNYNSKDLMKMIEHSIPENMFYKDVYGNYIGFNSGFLNLACMNKE
                     ELLGKNSYKISEEEALIDKIFESDKGVVENKKVVTFELNISMNDENKCIEITKRPFFD
                     SYGSVIGIIGTARDISRRKRLEEEMDKTRMEFFANLSHELRTPINLISSSLQVIEKKE
                     ADLIESNDTLKRNLGIIKQNGNRILRLVNNVIDFTKMQSGYLDFKPEESDIIAFIEEI
                     CMSVADFASQNNIQLTFDTEIEEFSMLFDSEKLERIILNLLSNGIKYNKKDGKINIFL
                     YVKDNVFNMKISDSGIGIPKEKIDKIFNRFEQIDNELSYRVKGSGIGLSLVKSLVELH
                     EGSISLKSQLGIGSEFIVSLPVRSKNNIEKYNHKREISNELSKKLEIEFSDL"
     misc_binding    27042..27282
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    27348..27583
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            27668..28885
                     /locus_tag="PC512_000837"
     CDS             27668..28885
                     /locus_tag="PC512_000837"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HDF2440607.1"
                     /translation="MENKVKIGVLGYGVVGSGLIDIIDNNKEKRNIEIVGILVNNLEK
                     HKDKKYSNIITNNIDDIFNKDIDILVEVMGGLEPSLSYIKKALNNKIHVVTANKDLLA
                     ECGDELAKLASENKVSIKFEASVAGGIPVLKPIIESLEGNNIDSINAILNGTTNFILS
                     KMYDENLSYDMALRQAQELGFAEANPESDVLGYDAARKLSILSTLAYDNRVYWKDVYL
                     EGITDIDEKDIEYAKKLNCKIKLIGQSKYENDKVSAFVRPVLVEKDNILARIDNEFNA
                     VIVNGDSVGEVSFVGKGAGSLATGSAVYSDVIDIIDNRVSSIDSFTKDKIQVNKIVRE
                     KCGALLRFKKCNKDEILNIVENCLVKFDILNDDDELAIMVYADSEYEINNSLCLIKDK
                     GYCEKMNKMLKIS"
     gene            29002..29496
                     /gene="cdeM"
                     /locus_tag="PC512_000838"
     CDS             29002..29496
                     /gene="cdeM"
                     /locus_tag="PC512_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium morphogenetic protein CdeM"
                     /protein_id="HDF2440608.1"
                     /translation="MENKKYANGGYSEDWYERGESTAKWFQNDREEYERAAYDEDRER
                     RGSNCGCSDSGENRPRNCERFRREAEIREREAREAFCESSERKKEALAYECEARKLWE
                     EAEKYWDEYSKYNYKGIEYLAEAARLFDEGMECEARRNGNNGGNNNNCCHKCHKCNCN
                     CCRK"
     gene            29761..31026
                     /gene="hisD"
                     /locus_tag="PC512_000839"
     CDS             29761..31026
                     /gene="hisD"
                     /locus_tag="PC512_000839"
                     /EC_number="1.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol dehydrogenase"
                     /protein_id="HDF2440609.1"
                     /translation="MKSIKTSSMKEKVDEKILREQVSSIIEDIRNNKDVALKKYNEKF
                     DRNTRDEFRITKEEIKEAYKHVDDEFINNLKIAAKNIREFAKAQKLSFENPFEKEIYP
                     GVILGQTNIPIESCLAYVPGGQYPLFSTALMLIIPAKVAGVKRIVACSPTMKNTEKIN
                     PKTLVAMDIAGADEIYATGGVQAIAAFTYGTEKINPVDIIVGPGNKFVTEAKRQCYGQ
                     VGIDFVAGPSEVLIIADETSNPVYIAADLLAQCEHDLNARGILLTNSLEVAQKVEKNI
                     ESMLKDLPTKDIAYSSWENNGEIILVDDMEEAIKISNFYAPEHLEVAVNEYNDICDRL
                     TNYGSLFIGNLSAEVFGDYVSGTNHTLPTLKASRYTGGVWVGTFIKTCTKQIFNEKAI
                     QSLAPVAEKLAKEEGLYAHAKAAEVRFKK"
     gene            complement(31229..31981)
                     /locus_tag="PC512_000840"
     CDS             complement(31229..31981)
                     /locus_tag="PC512_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2440610.1"
                     /translation="MSYFQYQGNSCFYKEYGQGKPIIFLHGNTGSSNMFKALVPLYVE
                     NFRCILIDFLGNGQSDRVSQFSPDIWHDEALQTIALIEHLNCGKVGLIGTSGGAWAAV
                     NTGLERPDLVEAIIADSFDGRTLNDNFIDNLITGREKSKQDIQARKFYEWCHGKDWEN
                     VVNLDTKALLQCANEKRPLFHKELCKLEMPILFTGSKEDEMCRHNLEEEYKQMATFIS
                     KASIHIFSQGGHPAILTNADEFAQLAKVFFKY"
     gene            complement(32099..32368)
                     /locus_tag="PC512_000841"
     CDS             complement(32099..32368)
                     /locus_tag="PC512_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440611.1"
                     /translation="MSYQNSIDLLPKELIEQVQEYIDGKVIYIPKKQEHKKHWGENTN
                     TKQVLASRNSQICINFQNGMSIKQLSEKYFLTEKSIQRILKQQNL"
     gene            32843..33937
                     /locus_tag="PC512_000842"
     CDS             32843..33937
                     /locus_tag="PC512_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDF2440612.1"
                     /translation="MKNIVGKPQTIKKVNEDLIKNIIKNEGPITKPEISNITELSLAT
                     VNKIVEQLALKNEVKVSGLSESTGGRRAQLFEINANLEHIIALYYYRNCCIGVVANLL
                     GEIIYQEEFNIRMDTYENVNQDTFFVIDTLIKKEKGNNIRAIGIGVPGVVKKGVVKNI
                     PTIKSWEGINLENLIKSKYNTKVFIENDTNITTIGIYQKQYKDKYKNMALMYLEDGIG
                     SGIVINGELYLGSTNFAGELSYLNIEFGKYNSNNLNLEDYIMSLRKRYLESKDNKFKK
                     EILSIISNFIRTLVCVLNPQAMIIQCSILTKSDMEFIEKDVSNNVGEENFPKLIKVES
                     LREGSINGVISMCLKETDYQYSLSNKKGGY"
     gene            33939..34889
                     /locus_tag="PC512_000843"
     CDS             33939..34889
                     /locus_tag="PC512_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine kinase"
                     /protein_id="HDF2440613.1"
                     /translation="MKYLVSIDGGGTKTKFCVSDLDGNILKEHTTGSTNYKSVGIKKT
                     YENINNGFKKILKDLYIDYDDIEYTVFGISGCDSPNDYKIIMDEILKIGINKEKIYLA
                     NDAVLAFYAQADSPGLVIVAGTGSIILGIKEDGEIYRVGGWGYNFSDLGSGYDIGRKL
                     LKKVLLYCDECHEYSDLFSCVLDFFGANSFEQLAYMITDINNNVEIANLASLVIDCAE
                     QGDKLAIEILRESSTELSKLAQVILRKISNPMKVDKSEINIVLSGGTLNKTVYAQMLM
                     NNLKTENTDKNLKFISQENQPVYGGIRLAMALANRRVKHG"
     gene            34882..36066
                     /locus_tag="PC512_000844"
     CDS             34882..36066
                     /locus_tag="PC512_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440614.1"
                     /translation="MDRKKVIVQIFTGGFKAKEIKFNDIKCKLLELLDCIDIEKVIMG
                     WSVDEELYVETKKLLNKYNVELYLWLPCFSEIGLLEKSNLLIDYMGKEVKGYALQEDE
                     NFEFYCPNNKENIKNIKKIYSTYFSDIKFDGIFLDKIRYGSFSNKLNGVFNCFCKDCL
                     NIYEKNNIDKESLMREMNNVSKGVIDNEDTPFGITEYINGKYKFKNKIWEDFFETKNQ
                     NIYKALLEISNYFKSKGLKIGIDTFSPFISYFTGQDLEKLQEVADFIKPMMYRTTKAP
                     AGLPFEFERFIDESIHKNKEIGKRNFLDILGIKEYEGDVYPIEFVLEEIDFMTRNLNK
                     DIYVGVEINKKEIISPVTPKYISENISNINKTTVKGYVLSWDLLSAPKENIDEIIKWF
                     RN"
     gene            36079..37575
                     /locus_tag="PC512_000845"
     CDS             36079..37575
                     /locus_tag="PC512_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HDF2440615.1"
                     /translation="MSKILEMQQIYKSFGKVDVLKGINFELEKGEVRALLGANGAGKS
                     TLIKILGGVHSQTKGKVILTGNEIMFKNPHHSKENGISIIYQELSLIPTLTVLENIFL
                     GREILKGSVFLNKKDMLEECMKICEDFDFNIDPHMVVSNLSVANQQMVEIMKAVSCNS
                     EIIIMDEPTTSLTNNEKDGLFKIISRLKSKGKTIVYISHILEEVFKVCDSASIMKNGI
                     MIGTYDVEDLTKLKITQLMTGNDNHKLIEKKDYTFAKYEEPPVLEVKNISWSNKIKNV
                     SFKVYRGEVVGLAGLVGSRRTEIINLIFGIDNKDSGDIFINGKKVDITSPKVAIKNKI
                     GLIPEDRKNLGLILEQAIYTNSSSVQIDKFKKFLFIDRNKEIEFSKKGVKELGIKVND
                     VKQEVKELSGGNQQKVVVSKWLEKDLDLIIYDEPTKGIDIAAKEDIFNTIKEFSSKGI
                     GVIFISSDLEEVIRVSDRILVTREGSIVDDLKNENIQVQDIMNSIFNV"
     gene            37598..38548
                     /locus_tag="PC512_000846"
     CDS             37598..38548
                     /locus_tag="PC512_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2440616.1"
                     /translation="MKKAFEKLNLRDYGVLLGFLALCIAISIATPSFLGKQNILNLLR
                     QSSIIGIISAGMTFVIISGNFDISVGAVAALAGAITMKFATGGTNLFASMLLGVAICA
                     VIGLINGIVVAKINVPSLIATMAMVTIVRGLLLMLTGGYPITENIPILDYIGNGYLFN
                     IPIPVVIFFIVVLASFIVLNKTKFGRYVYSVGGNQEASKLNGINVDSHKVKVFIINAV
                     LAGIAGIVLTGRLGTATAIAGEGYDMDAIASVVIGGTSVAGGSGSVLKTVIGVLLMSV
                     INNSFNLLGIDVYFQYIFKGLIILAAVGFDSYSKKKLASR"
     gene            38569..39531
                     /locus_tag="PC512_000847"
     CDS             38569..39531
                     /locus_tag="PC512_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HDF2440617.1"
                     /translation="MKKLMKHLALLLSLVMIFGLVGCSNGGDKEKNGEKKIAVLLPGS
                     TGYFVATKQGIDAKSKELGVSVEYADAQWDASKQLSQAEDFMAKGVDMIALCGVDSAV
                     SERIVKAANDSDVPIVAFTNSIGSNPTGEFKGLVTYIGQNEEETGALTGKIAKNLLGE
                     TGGKAVLIEGVPGTTPQVLRKKGLEKELKDSNIEIVYNQTSNWEKEQALKVTEDLIQK
                     KTDFNVIICQDDNSATGAGQALKDAGLKDKVKVIGLGGSKDGLKAITDGLIDGTTYMS
                     AVEEGGLVIEKASKFLKGEKIEPVTQIKQVEVNKDNISEFKGEW"
     gene            39903..40535
                     /locus_tag="PC512_000848"
     CDS             39903..40535
                     /locus_tag="PC512_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDF2440618.1"
                     /translation="MARRLFLERIGLIFLGSAILAFGVYNFYYLNNITEGGVLGILLL
                     LKNLFNIQPAIANVVIDGLLLLVGYKFFGKKFLIYSIVASITFSVLYDLFEAIGPLVP
                     QSQNMLLSTILAGVTVGTGVGIVVKAGCASGGDDALALVISKTTSLNIGQVYLATDVI
                     VLLLSLFYLSAFDIFYSLIAVTISGKVIDFIYYHGKSLDMDISNDIVPEC"
     gene            40946..41038
                     /gene="kdpF"
                     /locus_tag="PC512_000849"
     CDS             40946..41038
                     /gene="kdpF"
                     /locus_tag="PC512_000849"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: protein motif:HMM:TIGR02115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit F"
                     /protein_id="HDF2440619.1"
                     /translation="MEGLPMWFLAVVIIMLIIYLVYALINPEKF"
     gene            41079..42761
                     /gene="kdpA"
                     /locus_tag="PC512_000850"
     CDS             41079..42761
                     /gene="kdpA"
                     /locus_tag="PC512_000850"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015391009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpA"
                     /protein_id="HDF2440620.1"
                     /translation="MFMVQIVIVLAIFMILVIPMGKYLYHIATNQKTFGDRLFDKVDN
                     FIYKVCSIDKKKEMNWKQYALALLFTNAVMVFIGYIILRTQSMHIFNPSGIKSMEQGL
                     SFNTIISFMTNTNLQHYSGESGLSYFSQMTVIIYMMFTSAATGYAAAMAFVRGLVGKK
                     KTLGNFYVDLIRITTRVLLPGALIIGLILVTQGVPQTFAGTETVTTIEGKLQDIARGP
                     VAALESIKHLGTNGGGFFGSNSSHPFENPTIISNIVEILSMMILPGACVVAFGHMIKN
                     KKQGWVVFGAMSIIFLIGLVVCFKAESAGNPILSQLGLNQSMGSMEGKEVRFGIAQSS
                     LFTTVTTSFTTGTVNNMHDTLTPLGGLVPLLNMMLNVVFGGKGVGLMNMLMYAIIAVF
                     LCGLMVGRTPEFLTKKIEGKEMKLIALLIILHPLLILMFSGLSVAIPAGLEGISNPGF
                     HGLSQVLYEFASSAANNGSGFEGLGDNTMFWNITTGIVMFFGRYVSIIVLLAISSLLA
                     SKKAVNESIGTLRTDNFTFTIVLVLVVLIVGALTFFPALALGPISEHLVLWH"
     gene            42786..44843
                     /gene="kdpB"
                     /locus_tag="PC512_000851"
     CDS             42786..44843
                     /gene="kdpB"
                     /locus_tag="PC512_000851"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010966942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpB"
                     /protein_id="HDF2440621.1"
                     /translation="METKKTKFITKDIFKTSIIEAFKKLNPKYMMKNPVMFVVEIGFI
                     VTLILTIVPSLFGDEGNNLRAYNGIVTIILFITVLFANFAEAVAEGRGKAQADTLKKT
                     RKDTVARVIDTLGNEKMISASELKLGDIVLVNAGEVIPNDGEVIEGIASVDESAITGE
                     SAPVMRESGGDFASVTGGTTVVSDWLKIRITTKPGESFLDKMIALVEGASRQKTPNEI
                     ALNTLLVGLTLIFMVVLISLYPMANYAGVKIPISTMIALLVCLIPTTIGGLLSAIGIA
                     GMDRVTRFNVIAMSGKAVEACGDVDTMILDKTGTITYGNRLASEFIAVGNADSKDLIN
                     YSVMCSLKDDTPEGKSIVDLGMKLGSTGKTKEAEEAEFVEFSAQTRMSGINLADGRAI
                     RKGAYDSIIKRVKESGGTVPEDLEENVNRVAKLGGTPLVVCVDNEIYGIIYLKDTVKS
                     GLVERFARLREIGIKTIMCTGDNPLTAATIAREAGVDGFIAECKPEDKIDAIKKEQLE
                     GKIVAMTGDGTNDAPALAQADVGLAMNSGTTSAKEAANMVDLDSDPTKILEVVEIGKQ
                     LLITRGALTTFSIANDVAKYFAIIPAIFTLAIPQMEILNVMKLSTSFSAILSALIFNA
                     IIIPCLIPLAMKGVKYRPMKSQAMLMRNMLIFGLGGVIVPFLGIKLIDLLITPLVMVL
                     NLG"
     gene            44862..45488
                     /locus_tag="PC512_000852"
     CDS             44862..45488
                     /locus_tag="PC512_000852"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit C"
                     /protein_id="HDF2440622.1"
                     /translation="MKTLKPALLVSIVLLVVCGLVYPLVLTGVSQVAFKDKANGSMIE
                     VNGVKVGSELIGQSFTDARFFKGRVSSVNYNTYTKEDLVPDKDGNTSYGGVSSGSFNY
                     GATNPELHDRVQKDIEQFLKDNPTVKREDIPTDLLTASGSGLDPNISPASAKIQIPAI
                     AKASGISESKLQKIVEDNTSKKLFGVLGEDRVNVLKVNVEVAKILGLI"
     gene            45725..46633
                     /gene="cysK"
                     /locus_tag="PC512_000853"
     CDS             45725..46633
                     /gene="cysK"
                     /locus_tag="PC512_000853"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HDF2440623.1"
                     /translation="MLYNNALELIGNTPVVRLNNLGCTNGCSNIYVKLEKVNPAGSIK
                     DRAVYEMLEGLEQRGELKKGDVLVEATSGNTGIALSMIGKLKGYEVVIVMPETMSVER
                     RDLMKAYGANLVLTDGKAGMAGSIEKANELLKENPNYKSLKQFENKDNPNAHYKTTAV
                     EIMNDVKDLDIFVCGVGTGGTLIGTARYLKEQNPNIRVIALEPKKSPAISENKTGPHK
                     IQGIGANFVPENYDSSVVDEVILVDDEDAFDTVKLLAAKEGILVGISSGANIFGAIEM
                     AKKYPDKKIVTVAPDGVDKYMSMGIF"
     gene            46660..47250
                     /gene="cysE"
                     /locus_tag="PC512_000854"
     CDS             46660..47250
                     /gene="cysE"
                     /locus_tag="PC512_000854"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HDF2440624.1"
                     /translation="MFKKINKDIEYIMKNDPAARSKIEVFLLYPSVHAMIMHRMAHAL
                     YKKKKLFTARLISQISRFMTGIEIHPGAKMGEGILIDHGMGVVIGETAEVGNRVTIYQ
                     GATLGATGKDTGKRHPTVGDDVLIGAGTKILGPLNIGSNSKIGANSVVVKDVPNGATV
                     VGIPAKIVKIRNLEPVKKNKKEVSYEYDELDNVYYI"
     gene            47410..47598
                     /locus_tag="PC512_000855"
     CDS             47410..47598
                     /locus_tag="PC512_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HDF2440625.1"
                     /translation="MKANVNQDTCIGCGLCPSICPEVFDMKDDGKSHVIVDEVPSDAE
                     ESAAEARESCPVDAIDVH"
     gene            complement(47652..48521)
                     /locus_tag="PC512_000856"
     CDS             complement(47652..48521)
                     /locus_tag="PC512_000856"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HDF2440626.1"
                     /translation="MKLNRNDSCWCGSTKKYKKCHMDMDNKIDSFAKLGHIVPTHDII
                     KNESQIEEIKKSAVINTKILDYISDKIEIGMSTEDINKLVHDFTLQNGAIPAPLDYNG
                     FPKSVCTSVNNEVCHGIPSKDIILKDGDIINVDVSTIFNGYYSDASRMFMIGNVNENA
                     KKLVQVTKECVQKGLEVAKPWGFLGDIGDVINSYAKKNGYSVVREIGGHGVGLSFHED
                     PFVSYVSKKGTEMLLVPGMIFTIEPMVNEGTHEIFVDEENNWTIYTKDGKLSAQWECM
                     VLVTETGVEILTE"
     gene            complement(48718..49962)
                     /locus_tag="PC512_000857"
     CDS             complement(48718..49962)
                     /locus_tag="PC512_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440627.1"
                     /translation="MENNLNTAKRNNTELLQNDSLKVNLQIGVDFTLLSKSLKAFYKK
                     EKDFYCIALAPCNVSSEKANRKISIYNMIKEINILIESITDKNELLSEELFTNNLSEF
                     YDESLDEIYIDLKQAYLYIKKNTDSLNIEDSIEYVFDVDISNDIKAKENPLINFNSLS
                     LVVWSGETKHILQQMNILDLEDIHSYSIENNTNITIYENNTLQYKFDEESENIKDSSI
                     DIIEQMLILPDDLNYDKDEVENMKNRLAKINIKYLQTLKEKDIKIKLINSNLTDEPEF
                     SDLKYQLPPCWVRSGKTWKDVPGIYRNNSIVAKIGYSNPSYANVHSSKNLELHETAHA
                     IDKNVLNKKSNSEEFMEVFAQERYKLYDPKQVAHAYISKFIEEFFAESFVHYYLDEDS
                     KNTLKENCPLTYDFLEKLELNY"
     gene            50253..50564
                     /locus_tag="PC512_000858"
     CDS             50253..50564
                     /locus_tag="PC512_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HDF2440628.1"
                     /translation="MYFTYIIRCKDDSLYTGYTSNIVRRMNEHKLGINSKYTRAKGFE
                     KLEVYFVTNTKSNAMKLEYYIKKLTRNKKLSIIKNPSILINLIDNKEDYIIGKEIEQL
                     T"
     regulatory      50657..50749
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            50849..51643
                     /gene="thiD"
                     /locus_tag="PC512_000859"
     CDS             50849..51643
                     /gene="thiD"
                     /locus_tag="PC512_000859"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HDF2440629.1"
                     /translation="MSNYKIPTLTIAGSDSSGGAGIQADLKTFSAIGTYGMSVITAIT
                     AQNTKGVFAVEDLNKKIIKKQIEAVFEDIPPRAVKIGMVSSPEIILEIVENLKKYNPK
                     YLVVDPVMISKSGYYLLKPEAKENLIKYLIPLAYIITPNIPEAEEITGIKIHNVDDMK
                     RVGEEILQLGPKFVLMKGGHLDGEAVDILVGKNIFKVYKSERIDKKNTHGTGCTLSSA
                     ITSYLALGYEITEAVNLSKIYITEAIKRSFDIGHGVGPVHHFYKFE"
     gene            51667..52455
                     /gene="thiM"
                     /locus_tag="PC512_000860"
     CDS             51667..52455
                     /gene="thiM"
                     /locus_tag="PC512_000860"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HDF2440630.1"
                     /translation="MYNLIKDVKKLNPLVIHYTNNVTINDCANVTLAVGASPLMSFSY
                     EEVEEMVSVANSVVINIGTMNSNMLDLFLLAGKAANKYNKPVVLDPVGVFASKARAEL
                     TSRLLNEVKFSVVKGNVSEIKFIGGFNVRGKGVDSFDEEEDSTEIIRKIAEKLECVVV
                     ATGKIDIITNGKGTYKINNGTDKLKGITGTGCMTASLIASFMAVTENILEAATMGVLT
                     MSLSGELANLNNPPIGTFKENLMNAIYQMDIDTLSKNSNIEFLN"
     gene            52478..53110
                     /gene="thiE"
                     /locus_tag="PC512_000861"
     CDS             52478..53110
                     /gene="thiE"
                     /locus_tag="PC512_000861"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HDF2440631.1"
                     /translation="MIDKESLKKCLKLYLVTDSEMLKGRDFYKCLEDAISSGITTVQL
                     REKNASGREFLRKAMKLREITKQYGVKFIINDRVDIALICDADGVHVGQSDIDVREVR
                     KLIGNNKILGVSARTLEEAICAKNDGADYLGVGSIFTTSTKLDAKSASFETVKEIKEK
                     VDMPFVLIGGINLDNIDKLKCLESDGYAIISAILKAEDISKEVEKWTLKI"
     gene            53249..53551
                     /locus_tag="PC512_000862"
     CDS             53249..53551
                     /locus_tag="PC512_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2440632.1"
                     /translation="MIRILLVCVGGMSSTLLVNKMEKDAKKRNIDCKIWAVGEGDIKS
                     ELDNFDILLLGPQLRFMLDDVKSIVGDRAPVSIIDMVNYGTCNGHAVLNSVLEILK"
     gene            complement(53617..54366)
                     /locus_tag="PC512_000863"
     CDS             complement(53617..54366)
                     /locus_tag="PC512_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2440633.1"
                     /translation="MLNILWRSMKWRFKNPISFVVTILQPFLWLVLYSSIANQTMNNI
                     NINNYTAFILPGIIVLVVFSSCSSGGIINFIMKNSGSFYRVLIAPISRYSIVLGQLLE
                     AILVSFIEVTILCIVSIFFSVRIESGIGGILLMIVLIFMTAFFLSSLAYSISLLLPNE
                     IVYETIMTAIVLPIFFLSSALFPIESLSGGLKVAVMLNPFTHVINALRSLIFGETILI
                     GDILPVILLFLILCCSSFSLAMWRLKKEMVS"
     gene            complement(54360..55322)
                     /locus_tag="PC512_000864"
     CDS             complement(54360..55322)
                     /locus_tag="PC512_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2440634.1"
                     /translation="MLAIEIDNLVKEYKNGVKALNGLSFNVNAGEIFSLLGPNGAGKS
                     SLINILTTFYKPTSGNVTMFGKDLVDNPSWIRTQIACVAQQISIDEHLSLMENMVFQS
                     KMYKVEPQIAKQRIDSLIDKFDLSSYLKYPTSSYSGGVKRRLDIAMNMVSSPKILFLD
                     EPTVGMDVDSRKSMWDMLLKIRDEYGTTIFLTTHYLEEAEQLSDNICIMKNGKDLAQG
                     TPSSLRSYIRQNILRITFHNTEDIKKYKDSIKSTGLVKFMSVRENSIFISVNDSRTAF
                     TLINKWLLEHDIEFDAIEIVEPSLEDVFLALTSSKKSLKEEWEC"
     gene            complement(55326..55784)
                     /locus_tag="PC512_000865"
     CDS             complement(55326..55784)
                     /locus_tag="PC512_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HDF2440635.1"
                     /translation="MNCKIEIKNIESVTVATMRYNGPMTEATKYFPNVFKAIKGKSNG
                     APFFCYYDVDQKTGVAEMELCVPTAETPNRMGITTKEFPKTKALFFTHTGSYSNLPKT
                     YEMIFKYIHENNIKIQTPWREVFIKGPGMLIKGNPDNYITEIIFPLKEEE"
     gene            56140..56496
                     /locus_tag="PC512_000866"
     CDS             56140..56496
                     /locus_tag="PC512_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2440636.1"
                     /translation="MNFELDNTTPIYLQIVKYIKRQIVTGELKPGETIPSRREMALNL
                     KVNLNTVQRAYKEMGDMNIINTFKNYQSSVTVDENILKNLKLELINESLSVFIEDMKA
                     INVSKEEVLKIIEDKY"
     gene            56568..57284
                     /locus_tag="PC512_000867"
     CDS             56568..57284
                     /locus_tag="PC512_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2440637.1"
                     /translation="MIEIKNVSKTYKRMQGLKIRKIEALKNVSFNIEKGKITALLGIN
                     GVGKSTMLKAIAGLINIDSGEIRIDGEKINEKVYNKLAFVPDVQSHFSNTTIKETFEF
                     MEIFYSKWNKEKSKEMMDIFKLDEDEIIDNLSKGNIARVKLILGFCQDPEYILLDEPF
                     TGIDLFKREEFIGVIAQYMEENQAIIITTHEIVEIESLVDEVVILDEGQIITSFNAEE
                     LREREGKSILDKMREVYKNE"
     gene            57277..58101
                     /locus_tag="PC512_000868"
     CDS             57277..58101
                     /locus_tag="PC512_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2440638.1"
                     /translation="MNKLLYLINVDLRRSNKFYIAYISFFSLITLSLNLFEINKFKNS
                     KFIMNLAIEDFGGIFYGLGILSNLGFIQSILFFGILGLFIYYVFMWKREFFSNNQSIY
                     TLMMLPQNKFKICISKSIALITMIYGFLISQTATLFICKYIFNFIFRNMPIINMNFAK
                     DLYYLNLKSIPIDFISFMAIYVFLLLIAISIVNCCILFIFSYINKFYVILITLLIIAG
                     LYFSTIYINIITLFRKYYNLIGFQFNNLVAGLLSFLIIMFILNGISYLLIKKKVSL"
     gene            58113..59312
                     /locus_tag="PC512_000869"
     CDS             58113..59312
                     /locus_tag="PC512_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440639.1"
                     /translation="MKLKSKISILIIFLTLAIYFSIGLLNNEDNLKIKTIKGDSNELD
                     HININFGYALNGYINSYYTINGSNKTKKTELIKLQKDSKNTNNLIDVSSGSDLIAHVG
                     FEMNEESKDINFVIDEKKEDLEKGVFPSEDSDKEIEYEKLDMNNFTRTRYKVDKSTDD
                     YYAKILSSKRYKKYLYVSVLYATSDSSENNKEYSSTIDIIKINPENKKIKTIKSINLS
                     NYFSEKYQNIENIGVSYASKYEDKMYILVNVLNTNIGDNSNSKFHLLEYNLEENKESI
                     MELKTDSKMALAKAKLEANKLYMVMSNDYDNSSITELNLLTYNILDKSLDEDKYVLDN
                     REKRGIRSIEIDSNKIVAYTSRLNSILSWDDKFMLYIINKNSKEIVYEGELQFNSSNS
                     MLEFEIK"
     gene            59321..60133
                     /locus_tag="PC512_000870"
     CDS             59321..60133
                     /locus_tag="PC512_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440640.1"
                     /translation="MKDLIRLFEFELKRNIKNYIFIIICCCSFVILNIVKNLNDYNYI
                     IENAVKSEQLTKIGNTIETVNVTGFSSFRNIMGSTELWFMFGIIACICYAFFIWYRDF
                     NGRSKSIYTLIMLPKNRINIYISKLLNILFLVYSYTVVLTISLFIASKLLPRHMLGNV
                     TNYGFVQETIYELKMLLPYSFEILFVEYIFLLIGFVSVVFTSILINKSIYKVSTLISF
                     LFLVIEILVFIISIEFIIPYEYSDVFTVLYSSINIFVCSLISNKLLKQKIDF"
     gene            60144..61412
                     /locus_tag="PC512_000871"
     CDS             60144..61412
                     /locus_tag="PC512_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440641.1"
                     /translation="MKAKNIGKYTICFIIVCFLMITMTLILSYFNKDKLSVKTLKGNV
                     KDIGRVSVVYTPNISKFSYEEVIISKNGVRNNTNPKSRIRNDYLNIDKKYSDFVNDKG
                     KEFIYKDDLNIGEAYTSVKSDLVQGMNALNDCIKVSNKNLKSGVEENFDINLNKSDFK
                     ENSWKTLFNKIYKGNLYMVISETNISGSKVNNICILKIDIKNKSYKLLNRFNLGLQNG
                     EQQNINEIKFSIGSKLYLEIVNNKSKNGYIEGHDSYSNFIIYDIEDNTFNISNKFMDN
                     LNKEKNANPKEIGLLSKTKLDYMVKNNKLNLIVTDMSNSITNLVYDINSNEIKLEDYE
                     ILDLKVDYNEASSGVRKVKLLDDKIYSISGIKNSISGELKGFKGIVDVVGTKPVKFQV
                     FDMKLKKNIYEAELINGDISLQEKLFFVAN"
     gene            61778..62959
                     /locus_tag="PC512_000872"
     CDS             61778..62959
                     /locus_tag="PC512_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HDF2440642.1"
                     /translation="MNKKYIKAGNLIDGTGNSIMQNKGIIIDGDTIVEIEDIRDDLNG
                     YDVYDYLDKTVMPGIMNCHVHLTMEPVGNPKIYYDNVSDVELVVNTIKQLDAYLDSGV
                     TYIRSLGCPKYVDVQLKNLIDKGSIDGPGIVTSGPVICMTGGHGYYFGIESDGVDECR
                     KSARTVLKNGVDCVKIMATGGVTTDGVEPGSPQLTLEEMKAAVDEAIKAGKITATHAQ
                     GRTGIKNAVLAGITSIEHGVYLDDEIIDLMLERGTYLVPTVAAPYFILNAGKESGITE
                     ATLRKCEIVAIPHKESFLKAYKKGIKIAVGSDAGTSYNEHGKTYYEMKLMSDYGMDNM
                     DIIVAATKTASELLRIDKNYGTLEKGKKADVIVVNGNPVENIDVLADVLAVFKLGKKV
                     R"
     gene            complement(63101..64018)
                     /locus_tag="PC512_000873"
     CDS             complement(63101..64018)
                     /locus_tag="PC512_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440643.1"
                     /translation="MENNKCREDFRFTQEYEEDYPNTNERYYENYQVADRYYNYPNKY
                     KEPKIKQCCCKKSMREALELLRYDALRPFVNFNQFAFISDFFIVGANLVGIDLSAPPK
                     DNLSGLDGTFERFSACNCDLIDIAGRVSYPIPVPLTLEGLINTIGTIPGVAELIALID
                     AVIPPTIDLGAILDAILAAIIDFILAASTPLANVDLASLCNLKAVAFDITPADYEDFI
                     ASLGYYLDKKHYKECNCNCDCDDCCCNKGILDNLYMSNINNQVTVVAGSLVLTGVEVL
                     GKKNDVIVLGNSNDSRIYFVCVDSIDYIA"
     gene            64271..65065
                     /locus_tag="PC512_000874"
     CDS             64271..65065
                     /locus_tag="PC512_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2440644.1"
                     /translation="MIEVDKLCKSFTRVVKDDKNKSSIRKLKKVKTKKEEFFAVNNVS
                     FKVMEGEIVGILGPNGAGKTTLLRMLGGILTPTSGSINISGYDYSIDRNSAKKEIGYL
                     SGNTKLYGRLSPRELLTTFASLYEMSKEDIEESIENIVKIMDMSEFIDNRIENLSTGQ
                     TQRTSIARCLIHSPKVYIFDEPTLGLDVLSSASIIDFMKNEKLRGKTVLYSTHYMEEA
                     ETLCDKIFMIHNGKIIASGTPQSLKEESGVNNLRDVFIKLARKEDI"
     gene            65066..67126
                     /locus_tag="PC512_000875"
     CDS             65066..67126
                     /locus_tag="PC512_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDF2440645.1"
                     /translation="MRSKIVKYIFKKEMLDILRDKKTLFMMIVVPLLLYPLLMLLMIQ
                     VMNMSASSMNSKDINIAFNNKPNKVLVSMIEDDNLEKDTKNTSNDKGKIRVLDVDNYK
                     KSLEENKIDAYIKMEEKKSSINYQIYINSSQENSSNALKRIETVLDKYKRFTIEKTLS
                     EKGLDVQATLEPITYSTVDVAKTEEVAGYFLGQILPFILIIGVLLGSIYPAIDVMAGE
                     KERGTLETLFTLPISNLELVMGKYMAVSLSAIVTAILNILSMGLTMAFILVSGGISSQ
                     FGFGNFNYGDLVLPIITTLICICLFSMVVSAISMCVCSLAKSFKDAQNYITPLMLIIM
                     IPSYVSMIPNIVLDRVTAVIPVVNISLLIKSVLSFKSDLNLIALVLASNVAFVILAII
                     LLSKMFNSEEILFGNSKSFSFLEKRSNIKKGSIPTVSDGVILYAVGLVLLIYVGSLVQ
                     IKFGMAGIIMTQFMIISLPLLFAYYIKADFKEVFSLKVPKLKHVFGSIVLWIGGYILI
                     MIITQLILFLFPQNMEVAESLNKALFIKDSVLLNLLAIALLPALCEEMFFRGFIFSSF
                     SKSKDKNKSIKLAIICSGVLFGIMHMDFIRIIPTSILGIIFAYSVYKSGSIFVSMLLH
                     FLNNSVAVVLNHYTTGNITNLYKFVEVDFSNLNVLKFALILLISLILIMLGLRVLDRK
                     SLRN"
BASE COUNT        26498 a         6962 c        11519 g        22178 t
ORIGIN      
        1 taattatcta attatattta aggataataa tatgaaaata atttttatat taaaaaatat
       61 gaatgaaagt agtgggtttt ataaaaaaac atatttagat tttaacatct aaaaggagtt
      121 ttcaaagcta atatttcatt tttaaataaa aaaataaaat attagttttg atttctggtt
      181 taaattgggt tataataaat tgtcaaatta tttattaata taaaatagac tataaaacaa
      241 gcaaaaatca tactattata taaaagacct taaagataga aaactacaga aagaagccaa
      301 aatgtttttg aaaaaaatga aattttattg caaaaaaatc aaaatgaatt taacttaata
      361 gttataatct atttttagtg ttacaaatat acaatgtata ttatacaata taaaaaatac
      421 atttacttag aagtattatt atatttggat ttttggtttt tataattttt ttatatttaa
      481 acatagctaa aaataaaaga ttacgaaagc taagtagagt ttattttatt ttaataaata
      541 ataaagctat ttttctatat attggcataa tatatgctta tttaactatg aaattaaaat
      601 taaataggat taatgaggag gaaaaaaatg ggaagtaatg aactgaaaaa gactcttggc
      661 gtatcagcag cattatcaac tgttgttggt tccgttatag gagcgggcgt attttttaaa
      721 ccacaagcag tctatacatt aactggagga gctccaggtc ttggtatatt ggcatggtta
      781 atagctggaa tcataactat aacagctggt cttacagctg cagaggtatc agttgcgata
      841 ccaaaaactg gtggaatgat ggtatatata aaagaaattt atggagaaaa attaggtttt
      901 ttaactggat ggatgcaaat tgtattattt tatccaggga tgatggcagc attaggtgtt
      961 atatttggag aacaagcatc agcactaatt ggtagtccat cacttttact tccaatagca
     1021 attggaatta tagtaatagt tgcagggctt aatatgttag gttcaaaaac tggaggagtc
     1081 atacaaactg tttctacaat ttgtaagtta ataccactta ttttaataat ggttgttgga
     1141 tttattaaag gtggtggaaa taatccaata cttacaccta tggttggtga aggattaagc
     1201 ctgggtagtg tactaggtca agttttaatt gctatattat ttgcttttga tggatggatg
     1261 aatgttggta ctttagctgg agaaatgaag aatcctggaa aagaccttcc aaaagctata
     1321 ataggtggat tgtcagttgt tatggctgtt tattttataa taaatttagc gtatctttgg
     1381 gtattaccag ctaatgaatt agcaaattat gcttctcctg catcagcagt tgctgaagtt
     1441 atatttggtt caatgggtgg aaaaataata tctgtaggta tattaatttc agtgtttgga
     1501 gcattaaatg gatttttact aactggttca agggtggcat atactttagc tacagataag
     1561 actttaccaa agtatggtat attttctaaa ttaaattctg ctcaagttcc agcaaatgca
     1621 atagcattag tatctgttat tgcatctata tatgctttgt caggtcaatt taatttatta
     1681 actgacttag ctgtatttgc tacttggata ttctatgtat taacttttat aggggttatg
     1741 aaacttagaa agactcatcc aaatatacca agagagtata aagttccatt atatcctatt
     1801 gttcctataa tagctatagc aagtggtata tttgttgtag ttaatcaatt gtgttttgca
     1861 ggtatgaaaa ctactatgat atctatagga ggtcttgtaa taacagctat aggcttacca
     1921 gtgtatgctt atatgactag aggagtaaaa agataaacca agtagtttac aaatgcttca
     1981 taattaaaat aaaagagact gtctcaaata gagataagtc tcttttttat tgttaaaatg
     2041 gtaaagatat gtttaatttt acaaaaaaag agcgttccat gaactaaaaa gtttatttta
     2101 aggtattcat tttattttta gttttttgat tataaaatta aacatctaaa aaattattta
     2161 ttttaaaata ctttatttta aagtgttttt tatcaaacta agtggtatct gtacaacaaa
     2221 tattatacat agcttttatg aaaattaaat ctttctgtta tatataatag aatattgtat
     2281 tatatagaaa atattacctg attaatatag tgatttataa atgagattag aaaattttat
     2341 ttgataacaa aaattagata atatgaatat ataatgtatg tattaaaaat gtggcaaata
     2401 gttgttttgc tatttattat ttgtttaata tttctaattt ataaaaaaaa aattataaat
     2461 tttaaaaatt ataaatgaca ttttaactag aattaattgt aaaaaacact atataatact
     2521 caattttcaa cattctatac aattatacag aaattataca gcataataat caccgaaata
     2581 acaaatttta aaaattaagc aaaacttttt gtcgaagttc aacgtctata tatatgtagt
     2641 gtaaattttt gggataaaat actacaaaaa tataaatgta aaaatatagt aatattggag
     2701 gtcgaacgat gagaaataaa aagaaaaaaa taaatagaaa gaagttgtat ttgcttttaa
     2761 gtgctattgt agtgtgtctg gcttttatag tagttggtgt tcgcgtcagc tctttaaata
     2821 tgaaggaaaa tgaaattagt agaaatgcaa aactgtcaag ttctactatt acagatatag
     2881 tatctaatac atcaatagaa gttagtaaag ggccaagtaa aagttctgga aaaatagcat
     2941 acataactat agatgatggt ccatctaaat ttactgacga gatgataaaa actttaaata
     3001 aatacaatgt taaagcaact ttttttatga tagatgggaa tatgaaggaa tatccacagc
     3061 aagttaaaaa tataattaaa aatgggaaca cagcaggttt tcatagtgta tcacatgata
     3121 ttcacaagct ttatgttact agtacatcag caaaagagga atttgataca aatgatcaaa
     3181 ctttttataa gataactggt aaacattcaa aagtaataag aataccttat ggaagcaaac
     3241 catatacacc acaagcctct tatcaggctt tagttgatgc tggatataaa atttgggact
     3301 gggacttaga tacagaagac tggagatcta attcttctca aattgtacaa aatgtaaaaa
     3361 atcatattaa gaatagaaaa ggtgaagata aagaccaact tgtagtttta atgcatgaga
     3421 aaaaacagag tgcagaagct ttagattcag ttttaaaatt cttatcagat gaaggttatg
     3481 aatttgcgcc agtagatcaa aaccaaatac caaaaaatta ttggttacgt aatttagagt
     3541 agttaaaata taagaatatt gattgatatt tttagaaatt gagaataaaa atgagtgagg
     3601 tgtaggtata ttgaataaaa aactttatat aggaatggtc ggaatattgt ctttgatgat
     3661 ggttggttgt aataaaagtt tagcaaaagt aaatgatgtg gaaatcacaa aagaacagta
     3721 caaaaaaaca aaagcagttt tatctgctac taataattat ataaatgggc agtctttaga
     3781 tgaattagaa aaaactttgg ataaaaaagg tagaaataaa ttagaaaatg ttataatatc
     3841 gtttatggtg gataatgaac ttttatatca agaggctaag gataaaggac taactccaag
     3901 taaaagtgaa gtagactcaa aatatcaaga actagaagat aagatgaatt tgaatacaag
     3961 ctataaggaa aaaatggaca aagcaggtgt tgataaagat tatttaaaac aagaaatatc
     4021 tagagattta gcaatagata aaaataaaaa ggcctttgaa gatagaataa acataagtga
     4081 taatgatatg gaagcctact atacaagtca taaaaaagat tttaatgtag aagaagtaag
     4141 tgcttctcag atacttatat cgactttaga taaaaataaa aaagaagtaa gcaaagataa
     4201 aaaagaagct ttgaagaaga aggcagataa tatattgact aaaatcaaaa atggagaaag
     4261 ttttgaaagt ttggctaaaa aatattcgga tgataaagca actggaaaaa atggaggaca
     4321 gctaggatat tttacaaagg atgataaaaa tgctgagttt acaaaggaag tgttcaaatt
     4381 aaagaaaaat gaagtttcaa atgtgtttga aactagttat ggatatcata tagtcaaagt
     4441 tactgataaa agagaaagac aaaaaagttt taatgagtgt cagagtttaa taagagaatc
     4501 tattttaaat gaaaagtata ttgagcatat aaaaaaactg aatgaagatg ctaaaataga
     4561 cagatagaat ttctaacagc tcaatcctag cctgtaatcg gagggagatt ttacaggaat
     4621 gtttaagagt ttaaagagaa cgaaagttga gaaatacatt atcgataata aagactcttt
     4681 ttatagaata gcatatagtt atacgaagaa tgaagaagat gccttagatg tggttcaaga
     4741 agccatgtat aaggcactat actcagtgga aaatattaaa gaagtaaatt atataaagac
     4801 atggttttat aaaattttag ttagaacgag tatagatttt attagaaaaa accgtaaata
     4861 taataatatg acagatattg accttataga tgagactgga gagtatgata aatatactga
     4921 tttggattta agaagagctt tggaagaatt acctattgaa tacaaatcta ttataatatt
     4981 aagatttttt gaagatttaa agattgaaga agtagcaata atattggatg aaaatgtgaa
     5041 tactgttaaa actaggttat atactgcttt aaaaaaacta aaattaaaaa ttgaagagta
     5101 gggataaaaa gaatgacaag caaagaaagg ttaaataagt taaaagatga gtatcataaa
     5161 attccaatac ccaagaaatt agatactata ataaatcatg aaaaaataga aaacatatat
     5221 cgagagaaaa ataaaaaagt aaatagatta agatttaaag ttgcaatagc ctttgcatgt
     5281 atatttacag tattagtaaa tataagtcct gtatttgcag acaatttttc taagatacct
     5341 gtaattggag caatagtaga agtaataact ataaaaaatt atagtttaaa aagtgaaaat
     5401 tatgaagctg agattgatat tcctaaaata cgaggtttaa aagataaaaa cttagaacaa
     5461 agattaaaca gtagttttat ggaagatgga aaaaggcttt atcatcaatt ccaagagaga
     5521 atggagaaga tacaatcatc aaagaataaa ggatataaat ctttaagttt gagttatagt
     5581 gtaaaaaata attctaaaaa atttctatca atagagatga caaaaaatga gatagaggct
     5641 tcatcatatg tgagtaaggt acattatact attgataaaa aaagacaaat agttttgact
     5701 ttgccaatgc tttttaaaga tgataagtat ataaaagtta taagtgataa tataaaagaa
     5761 caaatgagag aacaaatgaa aaaggatagt acaaaatcct attttataga tcaaaaaaaa
     5821 gacttgcctg ttgaagattt taaaacaatt aataagtatc aggattttta ttttaataaa
     5881 aatgaagacc ttgtaatttg ttttgatgaa tatgaagtag cacctggtta tatgggcgca
     5941 gttgagtttg taataccata taaagtaata aaagatttgt aaattgaata gtagtttata
     6001 tataaatctt ttaaggagga caatatgact acatataaaa aacttaaaaa atctatattt
     6061 aaaattgcta tattttcaat atgcttatta gtttcattag tagatacaaa ccctatattt
     6121 gcaggtagtt cctttaatga aacttcaaat agtgatacga taaaggtgtt aaatgctaag
     6181 agtatcaact ttaaacaaga caattatgaa gtgaatgtga gtattcctaa aataaaaggt
     6241 ttaaaagata aaactttaga gaataaatta aacaatgagt ttttgcaaga tgggaaaaaa
     6301 atttacagtg aatttcaaaa taaaatgaaa aaggaaaata ataagggtca tagataccta
     6361 aatgtaatcc ataatgtcaa aaataattct aaggactttt tatcaataga aatgacaaaa
     6421 gaagagatag aagcttcctc atctataact aagaagcatt acactgttga taaaaataga
     6481 ggaatactat taaatttacc aatatttttt aaagatagta gatatattag agctataagt
     6541 gataatataa aagagcagat gagaaatcaa attaagaaag atgatacaaa atcttatttt
     6601 atagaccaag ataaagactc gccagtgaaa gattttgaat ctataaataa gtatcaagat
     6661 ttttatttta ataaaaatgg aaatcttgtg attagttttg atgaatatga agtagctcct
     6721 ggttatatgg gagcagtaga atttgtgata ccaaataaag taataaaaag actaagatag
     6781 atatatagaa gatttttaga tagactggta aggagaatta tatgaatata tatgaacaag
     6841 caataagatt aatagaaaat aatgaggatt tcgcatttgc tacaataacg tctcattcag
     6901 gttcaacacc acgtgaaact ggagcaatga tgattgtgaa aaatgattct actatatttg
     6961 gctcagtagg aggaggtagt gtagaagcag aatgtataaa acatgcaatt aatgttataa
     7021 aaaacagaga atcaatgttg tataaattta ctctaaacaa atctgatgtg gcaaaactag
     7081 gaatgatatg tggaggtact ggagaaatac aaatagattt tatagatagt aaattaaaaa
     7141 gtaatataga aaaatttaat aagagactaa aggaaaatac aagtaaagca tatatatttg
     7201 gtgcaggtca tatttcaaga gatgttgctg tgatactatc tcttttagaa tttagaacag
     7261 tagtaataga tgatagagaa gaatttgcta atcatgaaag gtttccagaa tcagaagtag
     7321 tagttttaga ttcttttgaa aacataccag attttcccac tgacgaaaat agttatataa
     7381 ttattttaac aagaggtcat ctatatgatt caagtgcttt agaatgggct cttaaaagag
     7441 aggctggtta tataggtatg attggaagta gaacaaaaat tggattgact tatgaaaaac
     7501 tcatgaaaaa aggttttaag aaggaagaat tatcaaaagt acatgcacca ataggcataa
     7561 aattgaatgc tcaaacacca gctgaaatag ctgtatgtat agctgctgaa cttataaatt
     7621 gtagagctaa taaggaaaaa taaactaatg aacacaggga gtaaagatat tgatacttta
     7681 aaggttaatt ttagagggat tgaaataaaa gcagttttag tatataaaaa tagaaaaaat
     7741 atttctataa aaatagatcc atttggcaaa ataactgtaa tgagtcctcc taaaatatcc
     7801 aaaaaaataa taaaagatat aattattgaa aaaggagact ggatacttaa aaagtcagaa
     7861 aaatgtaaag gaagagagga agtatataaa caaagaatgt ttataactgg cgaaaaattt
     7921 ctttatttag gtgaagagta ccatctagtt ataaaagaac tgttgagaga ttctgtcaaa
     7981 aaaagtaact gtagaataac tattaacgaa tatcaaatag ttgttcagac aaatgataca
     8041 agtacagatt ttattaaaaa atctttaaaa tcttggtata agatggaaag tgaaagaata
     8101 gtattagaga gaatagattt tcttaaatta aattgtgaaa taatgaagca attagttcca
     8161 gcgagtgtta aggtaaaaga acaaaataag agatggggaa gttgtacagc tcaaaaaaat
     8221 atttatataa actcaaaaat atctatggca agattagatg taattgatta tgtaataata
     8281 catgagttta gccatttagc acatatgaat cactctaaaa aattctatga tttagtaaaa
     8341 tccattatgc ccgattataa agataaagaa aattggctaa aaataaatgg atataaaata
     8401 ataatctgaa aacgattatt ccaaaatata ggcgtaaagt ataaaagaag tattattgtg
     8461 aaaaaaataa ataatctgaa aattttaaaa aaagtcattg acattgtaaa tgatagagaa
     8521 tataatctat attaacaaca aaacagaatt gaaatataaa attaaaaaat taaaagcaat
     8581 gacagagaca acaatactaa tagtgttatc cacagagaac caatgttgct gagaattggt
     8641 gttaacagta gtataatgat cactctggag cttttgtact gaatattttt agtaagtaca
     8701 aacgtatgtc aacgttacat gactaaggtt aaggtaatta attacccgac ctgaaaaaag
     8761 aggggtagat gtatttttta tatctacaaa taaggtggta ccgcggaata taactttcgt
     8821 ccttataagt aatatttata ttgcttataa agatgaaagt ttttttattt taagtgatat
     8881 aaataaattt aatccatata aaattaataa aaaaataata aaaataagga gggattttta
     8941 tggaaaatac tgtatatgct aaattaaacc aaggaataga ttctttttta agagtggcta
     9001 tgactctaag aagaagagag gttgatatac aatcaataag tatgactgta gataatatga
     9061 ataattcagg tataaaatta atagtaaatg aagaaaagac atccttagat tctgtcttaa
     9121 accatatgaa aaaactacat gatataagag agataactgt tgaaagaatg agacattaat
     9181 taaatatatt ttataaaact aaagataaat atgcttattt taaaataaaa aactaaagat
     9241 aaatattaaa taagaaaaat cttagattaa aatataagtg tcattgaatt tattagttta
     9301 tcacagttaa taaatttatt agtttgttgt agctaataaa aactgaaaat tctaaaatta
     9361 taattgtaag attatataaa tttagaattt aaatctgttg aataatatta aaacaatgat
     9421 aatgagtatg aatttctaat aaaaataaat atcataaaaa taagaaaaag tattgggagg
     9481 aaatgaaaat ggcaagaatg tattatgaaa aagatgtgga tttagaggtt ttaaaaaata
     9541 aaaaggttgc agttttaggt tatggaagtc aaggacatgc acatgcacaa aatcttagag
     9601 ataacggtgt acatgtagtg ataggtcttt atgacggaag taaatcagca caaaaagcaa
     9661 aagaagatgg atttgaagtt aagagtgtag cagaagctac aaaagaaagt gatttgacaa
     9721 tgatgttaat gcctgatgaa aagcaaaaga aagtttatga agagagtgta aaggataact
     9781 taaaagaagg tcagacatta gcttttgctc atggattcaa tatacattat aatcaagtac
     9841 aaccaccaga atttgttgat gttgtaatgg tagctcctaa aggacctggt cacttagtta
     9901 gaaatgtatt tacaaaggga agtggagttc ctgcactatt tgcagtatat caagactaca
     9961 ctaaaaaagc tacagagaca gttttagcat atgcaaaagg gataggagca acaagagcag
    10021 gtgttttaga aactactttt aaagaagaaa cagaaacaga tttatttgga gaacaatcag
    10081 tactttgtgg tggaataagt gaacttataa aattgggata taaaacgctt gtagatgcag
    10141 gttatcaaaa agaagtagca tattttgaat gtttacatga aatgaaacta atagtcgacc
    10201 ttatatatga aggtggattt gaaagaatga gatatagcat aagtgacaca gcagaatatg
    10261 gagattatgt atctggtaaa agggtaataa ctgatgctgc aaaacaaggt atgcaaaatg
    10321 ttttagagga tatacaaaat ggaaaatttg caaaagcgtg gattaaagaa aatgaagaag
    10381 gacgtgaaaa cttcctaaaa actagagaag aagaatataa tacagaaatt gccgaagttg
    10441 gtagaaatct aagaagtatg atgtcattct taaaataaat atatattaaa tggattagtt
    10501 tgagggaaag agtggtgtat agtagtgcgt atgagtggag caaaggtaat tttagaatgt
    10561 ttaaagaaag agggaattga cacaatattt ggatatcctg gtggagccgt gatacctctt
    10621 tatgatgctc tatacgatta ttcagatgat tttaaacata taaggacatc ccatgaacaa
    10681 ggtttagttc atgctgcaga tgggtacgca agaagtacta atacagtagg agtttgtttt
    10741 acaacatctg gtccaggagc aacaaatgcc ataactggaa tagcaacagc ttttatggat
    10801 tcttcaccta tggttgtaat ttcagggcag gtgccaacta gtttattagg aaaagattct
    10861 tttcaagaaa ttgacataac tggagcaaca ttatctatga caaaacataa ttatttagtt
    10921 agaaacacta aagaattagt tcctacaata aaagaagctt ttagagttgc aaattcaggt
    10981 agaaaaggac ctgtacttgt agatgttcca aaagatttat ttttagcaga aatggatttt
    11041 agtggtgagg actatgattt atgtcaaata gatgattata tggattataa gagtgatttt
    11101 gatctagatg atgaaactaa tattaagctt ttaaatgaag caatagatat cataaaagaa
    11161 tctaaaaagc ctataatata tgcaggtgga ggtgttaaat cttcagacag tgaggaaatt
    11221 cttgaaaaat ttgcaactaa gatagataca cccgtactaa atacacttat ggggcttgga
    11281 aatatagata gaaagaatga attatctctt ggaatggttg gaatgcatgg aagtagagaa
    11341 agtaatttag cactttctaa ttcagattta gtaatagcga taggtgcgag atttagtgat
    11401 agagtgataa gtaaaagttc tgaatttgct aaaaatgcaa aaataataca catagacata
    11461 gacccatctg aaataagtaa aaatatagaa tctaatgtat ctttggttgg agatgtaaag
    11521 ctagtcctta gtttattaat tgaaagggtt gaaagtaaga ataatagcaa ttggaaagaa
    11581 gagataaaga gatttagaaa gagtgagggt gtacaaacat atgaatttca tccacaaaat
    11641 atactaaaaa aaataaatga aaaatatgaa acattaaaga aacccactgt ggtagtaact
    11701 gatgtcggtc aacatcaaat gtgggctgct aagtactgga attttaaagg taataaaagt
    11761 tttataacat cagcagggtt aggaactatg ggatttggtt taggtgcagc tattggaact
    11821 aaagttggta atgtagataa aaatgtagtt ttagtcactg gtgatggaag ttttagaatg
    11881 aactgtaatg aactagctac agttgcaaat tataatgtac ctatgcttat tttattactc
    11941 aataatagaa cattaggaat ggtaaggcaa tggcaaaagt tattttccaa tcaaagatac
    12001 tctcaaactg acattaatga aaatgtggat tatgttaaac tcgtaaatgc atataatatt
    12061 gatggatata aggtatccag tatggaagaa ttaggaaagg cgctagatat gatagatttt
    12121 aataaacctg tatttttgca atgtgatata gataaggatt atgatgttta tcctattgta
    12181 gcacctaatg atgcattgga aaatttgata tgtaactaaa acttatactg aatattgata
    12241 aaatttttta ttaaattttt attggtattc agtttttgtt gtttagagat agattggcat
    12301 tttttatttt tgcaaataaa tcaatgacta tataattaag aacttattaa attttaatta
    12361 tacaatttag aatagtatta caacttaagt aaataataat tttgaataat aatttacgga
    12421 ggtattcata tgtttaaaca cgataaagca ttattaaaag aagtaaaagt agaaagacca
    12481 aatcctcaat atgctgtttt aatgcaagaa cagttgggtg gtgcaaatgg agagttaaaa
    12541 gcagctatgc aatacttgtc ccaaagtttt agaataaaag accctcaaat aaaagattta
    12601 tttcttgata tagcagcaga agagcttagc catatggaaa tggtagcaca aactataaat
    12661 ttattaaatg gacatgatgt tgattataat tcagttaata caggcgaaat agaaacacat
    12721 gtattaactg gtctatcacc agtcttaata aactcatcag gagctccttg gactgctaat
    12781 tacgttacag ttacagggga tttagtagct gacttacttt caaatatagc ttctgaacaa
    12841 agagctaagg tagtttatga gtacttgtat agacaaatag atgataaata tgtaaaagaa
    12901 acaatagatt tcttacttaa tagagaagaa gcacataatg ctctatttag agatgcttta
    12961 aataaagtta aagatacagg ttcaaataga gattttggag ttacagaaga ttctaaatta
    13021 tatttcgatt tgtctactcc agggccaaat cacgatacta agatagatat taatcctcct
    13081 tcttttgaaa aacctttaaa aaaataattt gatatttttt atgttgtttt gttttagtag
    13141 ttataaaaat tatttactag gagaattaat tatatgaaaa attaaatatg tatggttaaa
    13201 aatgggtata cacttattat aagtgtatat ctatttgttt attgcaaaac atataataaa
    13261 ataacaaatg aggtggtatt ttggacagta atagaaaacc taataatcta ataaatgaaa
    13321 aatctccata tcttttacag catgcatata atcctataaa ctggtatagt tggaatgatg
    13381 aggcttttaa aaaagcaaaa gaagaggata agccaatatt tttaagtgta ggatattcaa
    13441 catgtcattg gtgccatgtt atggaaaaag aatcttttga agatgaagaa gttgctgaaa
    13501 taatgaatag aaactttgtg gcgataaaag tagataaaga ggaaagacct gatgtagata
    13561 gcgtgtatat gacagtttgc caagccatga caggtagtgg tggatggcca atgaccataa
    13621 taatgacacc agataaaaaa cctttttttg cgggaacata tttcccaaaa tattcaaggt
    13681 ataatagacc tggagttata gatttattag agaatgtatc tgaaaagtgg aatacaagca
    13741 gggatatatt aataaaatct ggagatgaaa taatagaagc tcttaaggat gattttggtg
    13801 taaaaaatac tgagggtgat ttatcaaaag agatgttgag ttcatcagtt agagtattta
    13861 aggctattta tgatgaaaag tatggtggtt ttggtaatgc tcctaaattt ccaagtcctc
    13921 agaatcttat gtttttaatg aaatattata gtatagaaaa agacaaagat gtgttaaaaa
    13981 tggtggaaaa aactttagat ggaatgtata gaggaggctt gtttgatcat attggatttg
    14041 ggttttcaag atactctact gataaaaagt ggttggctcc tcattttgaa aaaatgctat
    14101 atgataatgc tatgcttact atagcttttt tagatgcgta taaaataaca aagaaagagt
    14161 tatataaaga aattgctata aaaactatag attatgtagt tagagagatg aaggataaag
    14221 aaggtgggtt ttattcagca caggatgctg atagtgaagg tgaagaaggt aaattttata
    14281 catttaatcc tcttgagata attgaagttt tgggtgaaga agatggaatt ttctttaata
    14341 attattttga tataactagt agtggaaatt ttgaaggcaa aagtattcct aatcttataa
    14401 aaaataaaga atatgagaga cataatgaaa agatagctga ccttagtaaa aaggtatttg
    14461 aatatagaaa agaaagaaca tctttgcata aagatgacaa gatacttaca tcatggaatg
    14521 cattgatgat agttgcttta acaaaggcat atagtacttt aaaaaatgac atatatttag
    14581 agtattcaaa taagtgtctt aactttataa ataataatct tgtaaatgag tcaggtagat
    14641 tattagctag atatagagat ggaagttccg actatttagc atatttagat gattatgctt
    14701 ttttaatctg ggcgtatata gagctttatg agtcaacatt taatatgaaa tatttagaaa
    14761 aggctttaaa tttgaatgaa agctgtatca accttttttg ggattatgaa aaaagtggat
    14821 tttatatata tggtaaagat agtgaaaatt taatagcaag accaaaagat ttgtatgatg
    14881 gagctattcc atcaggaaat tctgttcaat tatacaatct tataagactt gcgaaaatta
    14941 ctggagataa tagacttgaa gaaatgtcat ataaacaatt aaaactgtat gtggataatg
    15001 taaagagttc tccaactggc tacagctttt atatgctttc attgatgttt gaactttatt
    15061 ctactaagga aattatatgt atttttaagg aagattctga tttaattgca tttaaagaat
    15121 tgataagtga aaattttata ccaaatgcaa cttttttagc aaagaaatac aatgaagaaa
    15181 acactattat aggtttttta aataactata tattgaagga tgataagact agttattacg
    15241 tgtgtcaaag taatagttgt agtcaaccaa ttaatgattt acaaaaatta aaagatatga
    15301 ttttaggagt agaataatca taatagcgaa aaaggagatg ctttaaaata aaagtctaat
    15361 catctccttt ttttgtataa aaaacagaaa aagagttcct aagaacacct aatctatgta
    15421 atgattgttt tgttaaaaaa taaaaatgac attatagtta tataaaatat tgtactataa
    15481 aaaagtggta ttatagatgc gatagtatta atctttttta tttaccctat ttcttctttt
    15541 tgcaaattct tcaagtgctt cagatttaat tttatctatt tcttcatatt ccataaaatt
    15601 agcatcttct tcaaagccat cttgttcttc accattaaaa cgatacattt tttttagtaa
    15661 actccataag gtctctaatt catctttggt aaattcgtga aatacatctg ccataaagtt
    15721 tattccagtc ctactacatg ttaccataac cttttttcct aagtctgtaa ctttaacatt
    15781 aattgctctc ttatcatgag gacttggaat tacatcaaca tatccatttt tttcaagatt
    15841 agcaactagt ctatttatat tttgtttact tgtacccatt tttcttgcaa tattatttaa
    15901 tgttgtttct tcctctggta aatgaagaat tgataaaata gtcatatact gtcttgaagt
    15961 aagtatacca aaatatttat ctccttctat ttgtattttg tttgtaaggg taaaaagagt
    16021 tgcatatgtt tgattcatta aaaagagctc ttttagttca tttgaataat ccatgaaata
    16081 tatctccttt atttttagat gttgttttgt cgaaaacaga atatcatgaa ttaattctaa
    16141 tgtcaatatg gtgtcaaaat atattaaagt attacttttt tatgtaacta ttaattaatt
    16201 aaattattgt ataattttat gtaaaaactt ctatgtacca atgataattt ctatgaggaa
    16261 ttaataattc ttaaattttt tagaaagatt ttgacttgaa aatacttgta atataatata
    16321 taaattaata tactgaataa aatcaatctg gagggataat tatgaagtgt acaaacttta
    16381 ctttcaaagg agaggaaggt ttagatatat atacatataa atgggaagat gaaaatataa
    16441 aaaaaccaaa ggcagttatc caaattgcac atggaatggc tgaaactgca caaaggtatg
    16501 agacttttgc caaggtactt actaaaaatg gttatatagt atatatcaat gaccatagag
    16561 gtcatggaaa aactgcaaag ataatagaaa atgttggaca tttagctgaa aaagaaggat
    16621 ttagatgtct tgtagaggac atgtatactt taacaaatat tataaagaaa gaaaatgaag
    16681 atttgccaat ttatctattt ggacacagca tgggttcatt tgcaagtcaa agatatataa
    16741 tggattacag taataattta tctggtctta tactatgtgg ttcaaatgga aagcaaggaa
    16801 tcattctaaa tcttgctcat ctgataatca atcgtgagat taaaaagtat ggaagacgtt
    16861 ctaaaagtaa taaaataaat aatttgatat ttggtggcga aataataaga agaaatgaaa
    16921 agactaagtt tgactggtta agtagagata aagaacaagt tgaaaaatat ataaatgacc
    16981 cattttgtgg agtagtgtgt agttgtggct ttttttatga tttagttcaa gggttaaaag
    17041 aaattgagga taaagaaaac ttaaaaaaag tgccacttga tatacctatt tacataatat
    17101 ctggagataa agaccccata ggaaaaaatg gtaaaggagt cttaagacta agggatagat
    17161 atataaaatt aggagtaaaa gatgtaactt gcaaacttta caaagatgga aggcatgaat
    17221 tgttgaatga aataaataga gaagaagttt ttgaggatat aatttgttgg ttaaataata
    17281 aaatagaaat attgtaataa aaaaatataa tgatatattt gctttaaatt tatttatata
    17341 taatatttga aaagtggatt atgtatatgc aaagtagaaa agagagagcc tagaagtgat
    17401 tttttgctat aatgccattt attgaatagg tgggtgttat tataaataaa ttattaacac
    17461 tcagtatgat tatcattgta tatggaattt attttattta aaattccttg aaagtttaaa
    17521 tatagtaagt tgtaataaag agaaaatcta aatatttaaa tgctatttaa tgtgaatcta
    17581 ttaattaggt tatacttaaa cttaattaat agattttata tttcaagcca atgagatagg
    17641 gttttagatt aaaatataac caatggttaa attacagaca ttttgttaac tttccctcga
    17701 tttactagta aatatttttt ttatatactt aaattacaac agatgtacta gggaggtata
    17761 tatgcaaatt aaaataggta aagtcataca gtgtcttaga aaagaacgaa atttaactca
    17821 agaacaatta gcaaagttta taggtgtgtc aacaccagca gtatctaagt gggagagtgg
    17881 aaattcttac ccagatatag aattattgcc tttattagca gactttttta atgtgtctat
    17941 tgataagctt ttaaattaca agattgattt aagtgaagaa gaagtaatga aaatttataa
    18001 agaattagaa tcaggctttg ctagaattga aattgattta tcaacagaag aaccaaaaga
    18061 agaatttaga caagacttag aatctgtaaa aaagctttcc aatatgtata tagagaagta
    18121 tcctaaaagc tatttattga agctaaggat atgttcgctg tatcagatgt attcatataa
    18181 atttggtaag agtgaactta atgacagagt aaaagaaaca atgaatattc ttgaagatat
    18241 agtgagaaat acagatgata tccaaataaa agaaacagct cttattatat tatcaaacgc
    18301 atattgtatg ttggaggatt atgaaaaggc agagttgtat ttaaatatga tacataagtc
    18361 aataggggat acaagtgtta atttagctat gatatattta aagcaaaata gacttgaaga
    18421 agcagaaata ttgcttcaaa ataaattgtt tagtaatgta tttaatataa gcatggattg
    18481 taagggaata attaatgtat acaaaaatca atacaaggaa ttaaagaaaa aattggagaa
    18541 tagaaatttt aataaaaatg caattgagag agaaatggag tatataaaaa ataagttgct
    18601 ggggtatgca aatctttctt tagaaataaa aaaaatgctc agtgaagata aaggtgcatt
    18661 ttttagtatg tatatggatt atatggaatt atctctaatt tttttatttt ttaacatgaa
    18721 agaagaagca aaaaaagcct tatatagtct aaaagaaata ttagaaaaat atcctataca
    18781 tgaaagtttg gatgtaagtc aaatgagatt ttttgataag gtagagtcta aaaatttata
    18841 tacttttaat atatatacaa acttgttaat tgtacttaat gatgatagtt ataatgagct
    18901 tagagaagaa ccaattttta aggatgtaat tgaaaagatt ttagatatgg aaaaaatgtt
    18961 gaaaaataaa gaataagtaa aaatttaata taggacttaa agattaatca aattaaaaga
    19021 aagtgtttca aaataaaaat ttgaatcacc ttttttgtcg gtcttaaaca gttatttaga
    19081 aaaatagagg tttcaaaata gaaatctgaa ttatctgtat tattacacaa aaatagaaac
    19141 ctaaatttat aaaaatagaa taaagtttgt tatataaaat gtaattttgt ctataaaatc
    19201 tcacttgttt tcttaacttt aagcgtgaaa aagagaatgt atcatgaatt ttttagttca
    19261 tgatgcatcc ttctttgtat gaaatccaat atatctttat tatttaaaca atggaaaaga
    19321 gccttatttc tattttgaga catctctttt atttaattat gaagttttat acagttcaat
    19381 aaataggaat tatatttaga aactcatgac attatttctt agatagtgat taaatttatc
    19441 atattccatt ttagataact tttctgggta agacattaca atcaggttat gcccattaaa
    19501 tttttcatgg tatggtggat gaatgtgttc ataattattt gtcttatatt ttactctttc
    19561 atagaacgcc ttgcgataaa ttgaaatctc atcaattgga aggtcaattt ctaaaataat
    19621 agtttttcct ttcttattta aaagctctaa cgctctttgt ccatatctat tattgcgcat
    19681 ttctggaaaa atgcagaaat gttctacata gataaagtca tctgtttccc aacataaaat
    19741 tatgccgaca aactggtttt tatcataaat taaattgaac tgatattctt tatttttcaa
    19801 aatttcttct tgcaaagaag attttctttg ttcatgaaat gggaaactaa ttttatataa
    19861 ttccatagcc ttgtaacata atttattttc actggttctt aaccgtttaa atttcacttt
    19921 actcctccta atcacgaaaa ttccaattta tttatgagtt cattttacca tagtcagtat
    19981 ttgcatacaa tgtgttttaa gttgagtgtc atttctttct tttatttatg cttatatctc
    20041 atagactaag agataattgc ttaagacata actaaaaact attatattaa gctttgataa
    20101 tctaaaaaca gtatatttat ggacttttct aggtctaaaa gtaatcttaa taattttaga
    20161 agttacaaaa aagttacata aatttggaaa gctataatat acatatataa tataaggtta
    20221 aaactgtaat gaataatatt aatttaaaat ttgaacatgg aaggagatta ttatggagaa
    20281 aagagaaaag aggataataa tatcatcttt attaagtgta tcaattttaa tgggtttggt
    20341 aagtatatat tctatattaa ataaagaaga cataatttta actgttaagg gtcaagagca
    20401 aaaagtatct tcctttaaga aaacagttga ggaacttttg gatgaacagg gtataaagta
    20461 taattctgaa gataagatta atccaagttt agatacagaa ctaaaagatg atatgaaaat
    20521 aaaagttgtt aaggtaacta aaagtaaaaa agaagagatt gaaaaaattc catttgatac
    20581 aaagcatgta aatgatagta atttgttaaa aggaaaatct aaagtttatc aagaaggtca
    20641 agaaggagaa aaaaaactag tctataattt aacttaccat gatggaaagt tagtcaaaaa
    20701 agtcttatca aaagaagtaa tatctaagga gccaactaca aaaattataa aatatggaac
    20761 taaagaaaaa gtactaatag catcaagagg agcaaatata agaggaggca aacatatgaa
    20821 agtggttgcc actgcatatg caggagatac aataacatct actggtacaa ctccaagatg
    20881 gggtgttatt gcagttgacc cacgtgtaat accatatgga acaaaagtat atatacctaa
    20941 actgggtatg acttttgtag cagaagattg tggaggtgca attaaaggta atagaataga
    21001 catttttatg aacagtgaag gaaaagcttc aaattgggga aggaaaagta tagatatata
    21061 tctacattaa attagtgaat agaataactt tacttgaagg acaaaaaagt ataaaatatg
    21121 aattaactaa actgttagat tattcttaaa acataaaaat atatctaagg ggggataaga
    21181 tgaaaatagt atgcttagga gacagtttaa cgtatggatt tggagtatca cgaagtaatt
    21241 catggacaaa cattgtaaat aaagagactc gattagaaat agtaaataag ggtataaatg
    21301 gtgatacaac aagtggtatg ttagctaggt ttaatgaaga tgttgtaaaa aattctcctg
    21361 atatagtttt tataatgggt ggcaccaatg attttattgc tggtgcggga aatgaaatta
    21421 ttaattctaa tataatggct atggtgcatc agtcatattc aaaaaatatt atacctataa
    21481 taggtatacc attaaaacca gatattccaa atgttaggga agattggagt tgttttactg
    21541 attttaatat agtatctcaa aacttagaat catatagtta ttggataaaa aaattttgta
    21601 tgacatttaa tactaatttc gtagattttt attcagaata taataaaaat atggaactag
    21661 aaggatataa aaaattatat tttgatgggt tacatccaac caaagagggt catagaataa
    21721 tggcagacat ttttattaat tcaattaata agtatataga agagttatag attacattaa
    21781 aatgcttgtt tatgcgtcag ttgcaataaa tacatacagt agagaggggt ttattatgga
    21841 ttatactaaa acttatgaag agtggataaa gggttcatat tttgatgaag atacaaagct
    21901 agagttggag aatataaaaa ataatgaaaa agaaatagag gatagattct ataaggattt
    21961 agaatttggg actgcgggtc ttagaggaat aattgaagca ggaacgaata gaataaataa
    22021 gtacacagtt agaagagcta cttttggatt ggcaaactat atattagaaa acacaacaaa
    22081 agaagaaaca agtagaggag tagtaatagc tcatgataat agacacaagt ctagacaatt
    22141 ctgtatagaa tctgcaaata ctttggcagc atgtggtata aaagcatata tatttgatag
    22201 tttgagaact actccagaat tatcttttgc tgttagaagc ttaaatgcaa tcgctggtat
    22261 agtcataaca gcaagccata atcctccaga atataatgga tataaggtat actgggaaga
    22321 tggagcacaa gttatgccag agattgcaaa tgcaataaca gagaaagtaa atagtataca
    22381 tgattatagt acaataccaa ccttaacgga agctaataaa aatttggtag ttttgttgga
    22441 cgaatcacaa gatactaaat ttatagaagc agtgaaaagc caaattataa gaaaagattt
    22501 agttaaaaat gtaggtaaaa gctttaagat agtttataca cctctttgtg gaacagggaa
    22561 tgttccaata agaagagcat tgaaagaagt tggttttgaa aatataattg tagttccaga
    22621 agaagaaaat ccagacccaa attttgcagg gcttgattat ccaaatccag aagagaaaaa
    22681 agctttaaat agaggtatat tactcgcaaa agaaaaagga gcagaccttg taatagcaac
    22741 tgacccagat tgtgatagag taggtgtagc agtaaaaact actacaggtg agtatgcttt
    22801 acttacagga aatcaaattg gtggtatgct gacacattat ataatagaag gattaaaaga
    22861 aaataataaa ttaaaagaaa atcctacaat aataaaaacc atagttacat cagaatttgg
    22921 agcagatata gctaaagcaa ataatgttga tgtattaaat gttcttacag gttttaaatt
    22981 tattggtgaa aaaataaaat tatttgaaca aaataaaaat agaagttatg tatttggata
    23041 tgaagaaagt tatggttact tagttgggac tcatgctaga gataaagatg gtgtagtttc
    23101 ttcattgtta atatctgaaa tggcagcatt ttactattca aaaggtatga gtttatatga
    23161 tggtttaata gaactttata aaaagtatgg atttttcaaa gaacagacta tatctttgac
    23221 tttaaaaggt atagaaggtg tagaaaagat aaaagaaata atatcttatt ttagagaaaa
    23281 tcaaattgat tatataaata gtattaaagt agttgataaa aaagattata aaaatggtat
    23341 agataatctt cctaaatctg atgttttaaa atactttttg gaagatgaat cttgggtagc
    23401 tataagacca tctggaacag aaccaaaact taaattttac atagctgtaa aaggagctag
    23461 tgatattgaa gcagataaaa agattcaagg tttgaaaaag tatatagatg acatggtcga
    23521 aaaattaaaa taaaatatta ttattttata agataatttt gtaataatat ttatttagct
    23581 gaaaattata atttactttc attgagtaga atatggaaat gttagtagaa ttgttatttt
    23641 cagcttttat ttgtgttatt tttacttaaa taattatatt atagaatgaa tctgagtata
    23701 attaatattg tataatgaaa ttaatttgat agaaaagggg atatttatgt ttggtataga
    23761 taagaaattg attgaatata taattgcaaa atccaattac agtgaattaa gttcaaagtc
    23821 agcagaagta tctttcttct taatgttgtc catatttcct tttttaatat ttacaataag
    23881 ttctatagct tatataccga ttcttcattt aaataagtat atagctttgt ttagaaatat
    23941 gatgccagaa ggtgcttttg ctgtgttatc ttcaatcata gtttctgcaa tagacaatag
    24001 aaacctgaaa tttttagcag tcagttttgt acttactatg tggacatttt caagagcagt
    24061 aaaagctctt attaaaggaa tgaatagagc ctataaagtt aaagaaacta ggtctttttt
    24121 taaaatttta tctatatcat ttttatttac aataatgctt ttggtcctta tttttttatc
    24181 tatgatattt ttagtttacg gtgaaaaaat aggttatttt atttttaatc ttgtaggatt
    24241 ggatgagata tttataaaaa tatgggatat tctaagatac actgtaggta taataacaat
    24301 aatagtgata tttacacttt tatataaata cactccaaat aaaaagttaa ctattaaaga
    24361 atctgcgcca ggtgctattt ttgctacttt tgcttggttt ttagtatcat ttttatattc
    24421 ttattataca aattactatg ctaactatga agtaatctat ggaagtatag ctgaaataat
    24481 tgtacttatg acctggatgt attttagtag ttggtctatc gttattggct atgaggtaaa
    24541 ttcaagattg tattttagaa agataagaca tgaaatgtta aagtaaagta tttaaaataa
    24601 aagagagtat ttagtattat aaatgtaatt gaattaataa agaaatattg acatttaagt
    24661 taaaaagtct agaatttttc tgggcttttt ttatttttag tataacttga caaattttat
    24721 ttaatgggat agttttaatt tataatcatc tttaaaaaga tgactattga taagtaagag
    24781 ataaaattgg taagtatcaa aaaatatact aaataaaaat tatagtccta atgagttaat
    24841 ttctgtattt tcaaataatg cagtatttag tcatgtgttt ttatatgcgc ctgtatttct
    24901 aattagcaat atattagaat aagctactgt aattagattt agaaaaaagc gacataaata
    24961 attataaaca aataataaat tacataaaat taaatttatt cacaagtata tcttataaaa
    25021 tatgttataa ttaatagaaa attgtcatat aattaattaa gtagtattat tataaataac
    25081 attgaaaggt agtggttaga atatggatac ccataataaa tatgtaaatt ttataaaaaa
    25141 tatacctgta ccttttttat attgtagaat tgtaaagaga caagaagata tagaatatcg
    25201 agtagaatat ataagtaagg gtatgggcaa agtattacaa ttagaagaag gtatttgtga
    25261 taaaaatata ctagatgtat tgcctgtatt taagtctaaa aaatatttca aagagttgtt
    25321 ctcaaatgaa gtggattgta taaaaaggta cattccgaca cttaaaaact ggataaatat
    25381 aaaaaaacag ataatagggg attcatacat aattttgtat tttggtaaaa ttgtatttga
    25441 ttatagacag ataatcgatt cctttgataa aaaggaaaaa gtagcttata ttaaagacga
    25501 agaaggcata tatatagatt gtagtgaaaa tttaatacca atattaaata acaacattaa
    25561 aacaacgaaa gatatctttg gtaaaaatga tatagaagta tggggagaga atacaggaaa
    25621 attatttaga gatgattata gagaaggagt atctagtaaa aaaagatttt tacaaaatct
    25681 ttttgaatat gaagaaacat tttttatggt tgaaaaatat tttttgtatg atgaagacga
    25741 acttttaggt actataggga tagtagacaa tataatatat agtggttaca gtaatagaaa
    25801 ttataactca aaagatttaa tgaagatgat agaacactca attccagaga atatgtttta
    25861 taaagatgtg tatggaaatt atattggatt taattcaggt tttttgaatt tagcttgtat
    25921 gaataaagaa gaattattag ggaagaatag ttataaaata tcagaagaag aagctttaat
    25981 agataagata tttgaaagtg ataagggtgt agttgaaaat aaaaaagtag ttacatttga
    26041 gttaaatata agtatgaatg atgaaaacaa gtgtattgag attacaaaaa ggccgttttt
    26101 tgatagctat ggaagtgtta ttggaataat tggaacagca agggatataa gtagaagaaa
    26161 aagattagaa gaggaaatgg ataaaactag gatggaattt tttgcaaatt tatcccatga
    26221 acttagaacg cctataaatt taatatcatc ttcattacaa gtgatagaaa aaaaagaagc
    26281 agatttaata gaatcaaatg atactttaaa aagaaatcta ggtataataa aacaaaatgg
    26341 aaatagaata ttgaggttag taaataatgt tatagacttt acaaaaatgc aatcaggata
    26401 tttagatttt aaaccagaag aatctgatat aattgcattt atagaggaga tatgtatgtc
    26461 tgtagctgat tttgcaagcc aaaataatat acaacttaca tttgatacag aaatagaaga
    26521 attttcaatg ttatttgatt cagaaaaatt ggaaagaata atattaaatt tactttctaa
    26581 tggaattaag tacaataaga aagatggaaa aataaatata tttttatatg tgaaagataa
    26641 tgtatttaat atgaaaatat ctgatagtgg tataggtata ccaaaagaaa aaatagataa
    26701 aatatttaat aggtttgaac agattgacaa tgaactttct tacagagtta aaggaagtgg
    26761 tattggactt tcattagtga aatctttggt tgagttgcat gagggaagta tatctttaaa
    26821 aagtcaactt ggtattggaa gtgaatttat agtttcattg cctgttagaa gtaaaaataa
    26881 tattgaaaaa tataatcata aaagagaaat cagcaatgaa ctaagtaaaa aattagaaat
    26941 agagttctcg gatttataag tttaaatata aaaaataaaa ttttaaaaaa gtattgacaa
    27001 ttgatttaga agggtttaaa ataaattaca acataataaa taaaaaggcg atgaatagga
    27061 agagtaaatc taattcgatt accagagaga agagtccgtt ggctggaaga ctttttaaat
    27121 tagagggatt gaaaactacc taggagctac tttctgaagt catctgcatt agtagatttt
    27181 agtaagaata gtcgttagct gcgttaaagt gtaaagtgag ttttcatgac atatgaaaac
    27241 taaattaggt ggaaccgcgg gaataatact ctcgtcctta tgttataagg atgagagttt
    27301 tttgttattt aaaaatataa acagtaatca taataattat agaaaatata aaagcaatga
    27361 ataggaagag taaatttaat tcgactatca gagaggaaag ttcacaggct gaaagacttt
    27421 ctaagtttga gaaattgaaa actacctagg agctgtggtc tgaagttact ttaaaaagtt
    27481 ttagtaagac taaccgttaa ctgcgttaaa gtgtaaagtg gattttatca ataaatgata
    27541 aaatcaaatt gggtggaacc gcgagtatag actcgtccct ttatataggg atgagtctat
    27601 ttttattgca ataaaagatt gaaaataaaa aaaaatcgga aaattataaa tttaggagga
    27661 aaataaaatg gagaataaag tgaaaattgg agtactagga tatggagttg taggaagtgg
    27721 acttatagat ataatagata ataataaaga aaaaagaaat atagaaatag ttggaatttt
    27781 agttaataat ttggaaaaac ataaggataa aaaatattct aatataataa ctaataatat
    27841 agatgatata tttaataaag atatagatat acttgttgaa gtcatgggtg gtttagaacc
    27901 atcattatct tatataaaaa aagcattaaa caataaaatt catgttgtta cagcaaataa
    27961 agatttgtta gctgaatgtg gagatgagct tgcaaaatta gcaagtgaaa ataaagtaag
    28021 tattaaattt gaagcttcag ttgcaggagg tataccagta ttaaaaccaa taatagaatc
    28081 actagaagga aataatatag atagtataaa tgcaatttta aatggaacta ctaattttat
    28141 attatctaaa atgtatgatg agaatctatc ttatgatatg gcattaagac aagctcaaga
    28201 attaggtttt gctgaagcaa atccagagtc agatgtatta gggtatgatg ctgctagaaa
    28261 actatcaata ttatcaactc tagcttatga caatagagta tattggaagg atgtgtattt
    28321 agaaggaatt acagatatag atgaaaaaga tattgaatat gcaaaaaaat taaattgtaa
    28381 aataaaattg attggtcaaa gtaagtatga aaatgataaa gtaagtgctt ttgttagacc
    28441 tgttttagta gaaaaagata atatccttgc tagaatagac aatgagttca atgctgtcat
    28501 agtgaatgga gattcagtag gagaagtttc ttttgtaggt aaaggcgctg gaagtttagc
    28561 aacaggaagt gcggtttatt cagatgttat agatataata gataatagag tttcaagtat
    28621 agattctttt actaaagata aaatacaagt taataaaata gttagagaaa agtgtggagc
    28681 acttcttaga tttaaaaaat gtaataaaga tgaaattcta aatatagttg agaattgttt
    28741 agtaaaattc gatattttaa atgatgatga tgaacttgct attatggttt atgctgattc
    28801 tgaatatgaa ataaacaaca gtttatgtct aataaaagat aaaggatact gcgaaaaaat
    28861 gaataaaatg ttgaaaataa gttaaaaaag aaaaaatata agtttatatg taacatattt
    28921 tgacgatttt aatactatat agtatgagat gaaacaaaac atctcataaa aaaattaaaa
    28981 ttcaagggag agatatgtta tatggaaaat aaaaaatatg caaatggtgg ttattcagaa
    29041 gactggtatg aaagaggaga atctacagct aaatggttcc agaatgatag agaagaatat
    29101 gaaagagcag catacgatga agatagagaa agaagaggct caaactgtgg atgttcagat
    29161 tcaggagaaa atagacctag aaactgtgaa agatttagaa gagaagcaga gataagagaa
    29221 agagaagcaa gagaagcatt ctgtgaatct tcagagagaa agaaagaagc actagcatat
    29281 gaatgtgaag ctagaaaatt atgggaagaa gcagaaaaat actgggatga atattcaaaa
    29341 tacaactata aaggaatcga atatttagca gaagctgcta gattatttga tgaaggtatg
    29401 gaatgtgaag ctagaagaaa tggaaataat ggaggaaaca ataataattg ttgccataaa
    29461 tgccataaat gtaattgtaa ctgctgtaga aaataaaaaa attaattgac aaatcaatag
    29521 ttaaaatata tcatattatg tataataaag agaaaattca gaaaaaaata atgattagaa
    29581 gaaatataag tatatttatt agacaaatag tgctcagtta gtgaggtgag tacaatatga
    29641 ttaaactccc atcctctagc ttttgataga gggtgggagt ttttatttat ttatatatct
    29701 taaatgagga taatattgta aaataaatga gtatgagatt gtaaaattag gaggtaaaaa
    29761 atgaagagta ttaaaacatc aagtatgaaa gaaaaggtag atgaaaagat attaagagag
    29821 caagtaagtt ctataataga agatataaga aataataagg atgttgcact taaaaaatat
    29881 aatgagaagt ttgatagaaa tacaagagat gaatttagaa ttactaagga agaaataaag
    29941 gaagcttata agcatgtaga tgacgaattt ataaataact taaagattgc tgccaaaaat
    30001 ataagagaat ttgctaaagc tcaaaaacta agttttgaaa acccttttga aaaagaaatt
    30061 tatccaggtg taatcttagg tcaaactaat attccaatag agtcatgtct tgcatatgtt
    30121 ccaggaggtc agtatccatt gttttcaaca gctcttatgc ttataatacc tgcaaaagta
    30181 gcaggagtaa aaagaatagt ggcatgttca ccaactatga aaaatactga aaagataaat
    30241 cctaagacat tggtagctat ggatatagca ggtgctgatg aaatatatgc aactggagga
    30301 gttcaagcta tagcagcatt tacatatgga acagaaaaga ttaatccagt tgacataatt
    30361 gtaggaccag gaaataagtt tgtaactgaa gctaaaagac aatgttatgg acaagtaggg
    30421 attgattttg tcgctgggcc aagtgaagtt cttataatag cggatgaaac ttcaaatcca
    30481 gtttatattg cagctgattt attagcacaa tgtgagcatg atttaaatgc aagaggaata
    30541 ttattgacaa atagcttgga agtagcacaa aaagttgaaa aaaatataga aagtatgcta
    30601 aaagatttgc caacaaagga catagcatat agttcatggg aaaataatgg agagataata
    30661 ttggttgatg atatggaaga agccattaaa ataagtaatt tttatgcacc agaacattta
    30721 gaagttgcag taaatgagta taatgatatt tgtgatagat taactaacta tggttcttta
    30781 tttattggaa atctttctgc tgaggtgttt ggtgactatg tttcaggtac caatcataca
    30841 ttaccaacac ttaaagcatc aagatatact ggtggtgttt gggttggaac ttttatcaaa
    30901 acttgtacaa agcagatatt taatgaaaaa gctatacaat cattagcacc tgtagctgaa
    30961 aagctggcaa aagaagaggg attatatgca catgcaaagg ctgctgaggt taggtttaaa
    31021 aagtagtaaa aaattttatt ttggcagtcg agatttagtg ttagactgag ataaggaaaa
    31081 cgctgagaac ccgaataaat actatatttt gtgggcctcg gcgtttcttt tatatctgta
    31141 tataatagga taatactacc tgtgtgttta aatgctagct taatatttct tttctaaata
    31201 atgtttatga aatagttaat atttttagtt aatacttgaa aaaaactttt gctaactgtg
    31261 caaattcatc tgcattcgtc aatatagcag ggtgtcctcc ctgactaaaa atgtgaatac
    31321 ttgcttttga aataaaagtt gccatttgtt tgtactcttc ttcaagatta tgacgacaca
    31381 tttcgtcttc cttacttcct gtaaataaaa ttggcatttc taatttacac aattctttat
    31441 gaaacaaagg gcgtttctcg tttgcacatt gcaatagagc ttttgtatca agattaacaa
    31501 cattctccca atcttttcca tgacaccatt catagaattt tcgtgcttga atatcttgct
    31561 ttgatttttc ccttccagtg attagattat ctatgaagtt atcattaaga gtacgtccat
    31621 caaagctatc tgctataatt gcttcaacta aatcgggacg ttctaatcca gtattaacag
    31681 ctgcccatgc tcctccactt gttccaatta agccaacttt accacaattc aaatgttcaa
    31741 tcaatgctat tgtctgtaag gcttcatcat gccatatgtc aggagaaaat tgagaaactc
    31801 tatccgactg tccattacct aaaaaatcaa ttaagataca tctaaaattt tctacatata
    31861 atggcacaag tgctttaaac atattagaag aaccagtatt accatgcagg aaaattatcg
    31921 gtttaccttg tccatattct ttataaaaac aagaattacc ttgatactga aaatatgaca
    31981 tatattttcc tcctttttat ttgttaagtt aattataaca atataggtat gaatgaaaaa
    32041 cctcatgttc tttcttagaa taaaaatgtg ccacgcataa aacgtgacac atttctaatt
    32101 ataaattttg ctgtttaagt attctttgta tgcttttctc tgtcaaaaag tatttctctg
    32161 ataactgctt gatactcatt ccattttgga aatttataca gatttgagaa ttacgagaag
    32221 ctaagacttg tttggtgttt gtgttttcac cccaatgctt tttgtgctct tgctttttgg
    32281 gaatataaat cactttacca tctatatatt cttgcacttg ctcaatcagt tctttaggca
    32341 gtaagtcaat cgaattttga tagctcattt tgcacctcct aaataattat tctttaggat
    32401 tagcaaaggc tactgccact cacaattaaa aataaaattt tttattatgt acaatagcct
    32461 ttgctatgca caagttccaa ttcccataaa ctaaatactc ctttctggtt tgaaaaattc
    32521 atctgaacat tgatttcgct tttaagatag agttcaatga caaatttaca tttttattat
    32581 atatattcag atagataatt gcaactgtct ttgtatgagg atattttatt atagtcaata
    32641 ctataatatg tatttatatc atcaaactaa tatgaacagt tgaaaggaat atgaacaata
    32701 aaacttagtc aggaagaata attatgaagc agacaataga gaaatttgat tttaaagttt
    32761 tattgaaaat ttattgacaa atttaacttg taaatattat actaaactta ataaataaag
    32821 tttataaagt aaggtgttgt ctatgaaaaa tatagttgga aaaccgcaaa cgataaaaaa
    32881 agtaaatgaa gatttaataa aaaatattat aaaaaatgaa ggtcctataa caaaaccaga
    32941 aatttcaaac attactgaat tgagtttagc tacagttaat aagattgtag agcaattagc
    33001 tttgaaaaat gaagttaaag taagtggact aagtgaatct actggaggaa gaagagctca
    33061 attatttgaa ataaatgcaa acttagaaca cataatagct ttatattatt atagaaattg
    33121 ttgtataggg gtagttgcca atttattagg tgaaataatt tatcaagaag aatttaatat
    33181 aagaatggat acatatgaaa acgttaacca agatactttt tttgttatag atactctaat
    33241 aaaaaaggaa aaaggaaaca atataagggc tattggaatt ggtgtcccag gagttgtaaa
    33301 aaaaggtgta gttaaaaata taccaactat aaaaagttgg gaaggtataa atttagaaaa
    33361 tttaataaag agtaaataca atactaaagt gtttatagaa aatgatacaa atattactac
    33421 tattgggatt tatcaaaaac agtataaaga caaatataaa aatatggctc ttatgtattt
    33481 agaagatggt attggttcag gtatagttat aaatggtgaa ttgtatttag gttctacaaa
    33541 ttttgctgga gagttaagtt atctaaatat agaatttggt aagtataact ctaacaactt
    33601 aaatcttgaa gattatatta tgagtttaag aaaaagatat ttagaaagta aagataataa
    33661 atttaagaaa gaaattttat ctataatatc aaactttata aggactcttg tatgtgtcct
    33721 aaatccacaa gctatgatta tacagtgtag tatattaacc aagagtgaca tggagtttat
    33781 agaaaaagat gtaagcaata atgttggaga agaaaatttt cctaaattaa taaaagtaga
    33841 gtcattgaga gaaggaagta taaatggagt aattagtatg tgtttaaaag aaactgacta
    33901 tcaatattcc ttatctaata aaaaaggagg atattaatgt gaaatatttg gtttcaatag
    33961 atggaggggg aacaaaaact aaattttgtg taagtgactt agatggaaac atacttaaag
    34021 aacataccac tggttcaact aattataagt cagttggaat taaaaaaaca tatgaaaata
    34081 ttaataatgg atttaaaaaa atattaaaag atttatatat cgattatgac gatattgagt
    34141 acactgtatt tggtatatct ggttgtgatt ctcctaatga ttataagatt ataatggatg
    34201 aaatattaaa aattgggatt aacaaagaaa aaatatatct ggcaaatgat gcagttttag
    34261 ctttttatgc acaagcggat tcccctggtt tagtaattgt ggctgggaca ggttcaatta
    34321 tactgggaat taaagaagat ggagaaatat atagagttgg tggatggggg tataatttta
    34381 gtgatttggg ttctggatat gatataggga gaaaattatt aaagaaagta ttgctttatt
    34441 gtgatgaatg tcatgagtat agtgatttat ttagttgtgt cttggatttc tttggagcaa
    34501 atagttttga acaacttgca tatatgatta ctgatataaa caataatgtt gaaatagcaa
    34561 acttagcttc attagtgatt gattgtgccg aacaaggtga taaattggct attgaaatat
    34621 taagagaatc atcaactgaa ctatctaaat tagctcaagt aatattgaga aaaatatcta
    34681 atccaatgaa agtggataaa agcgaaataa atatagtttt gtctggtggt acattaaata
    34741 aaactgtata tgctcaaatg ttaatgaata atttaaaaac agaaaataca gataaaaatt
    34801 taaaatttat atctcaagaa aatcagccag tgtatggggg gataagactt gctatggcat
    34861 tagctaatag gagggtcaag catggataga aaaaaggtaa tagtacaaat ttttactgga
    34921 ggttttaagg ctaaagaaat aaagtttaat gatataaaat gtaaactact agaattattg
    34981 gactgtattg atatagaaaa ggttatcatg ggatggagtg tagatgaaga attatatgta
    35041 gaaactaaaa aactattaaa taaatataat gttgaactat atctttggtt gccatgtttt
    35101 tctgaaatag gattacttga aaaaagtaat ttgctaattg attatatggg gaaggaagtc
    35161 aagggctatg ctttacaaga ggatgaaaat tttgagtttt attgcccaaa taataaggaa
    35221 aatataaaaa atataaagaa aatatatagt acttatttta gtgatattaa atttgatgga
    35281 atttttttag ataaaataag gtatggttct ttttcgaata aactaaatgg tgtttttaat
    35341 tgtttttgta aagattgttt aaatatatat gaaaaaaata atattgataa agagtcgtta
    35401 atgagagaaa tgaataatgt gtctaaggga gttatagata atgaagatac tccatttggt
    35461 ataacagaat acattaatgg aaaatacaaa tttaaaaata aaatatggga agattttttt
    35521 gaaacaaaaa atcaaaatat atacaaggca ttattagaga taagtaatta ttttaaaagt
    35581 aagggattga aaataggtat agatactttt tctcctttta tttcttactt tacaggtcaa
    35641 gatttagaaa aattacaaga agtagcagat tttataaaac caatgatgta tagaactaca
    35701 aaagctccag ctggtttacc atttgaattt gaaaggttta ttgatgaatc catacataag
    35761 aataaagaga ttggaaaaag aaatttctta gatattttag gaattaagga gtatgaagga
    35821 gatgtatatc ctatagaatt tgtactagag gaaatcgatt ttatgacaag aaatcttaat
    35881 aaagatatat atgtaggagt tgaaataaat aaaaaggaaa ttatatctcc tgttacacct
    35941 aagtacataa gtgaaaatat ttcaaatata aataagacaa cagtaaaagg atatgtttta
    36001 tcttgggatt tgttgtcagc accaaaagaa aatattgatg aaattataaa atggtttcgg
    36061 aattagtgag gtgataaagt gagtaagata ttggaaatgc aacaaatata taaaagtttt
    36121 ggaaaggtag atgttttaaa agggataaat tttgagttag aaaagggaga agtaagagct
    36181 cttttgggag ctaatggagc aggaaaatct acacttatta aaattttagg aggagttcat
    36241 tctcaaacta aaggtaaagt aattttgact ggtaatgaaa taatgtttaa aaatccacat
    36301 cattctaaag aaaatggtat tagtataatt tatcaagaat taagcttgat accaacgctt
    36361 acagtacttg aaaatatttt tcttggtaga gaaattttaa aaggaagtgt gtttttaaac
    36421 aagaaagaca tgcttgagga atgtatgaaa atttgtgagg attttgattt taatatagac
    36481 ccacatatgg tagtttctaa tttaagtgta gcaaaccaac aaatggttga gataatgaaa
    36541 gctgtttcat gtaattctga aattatcata atggatgaac ctacaacatc acttactaat
    36601 aatgaaaaag atgggctatt taaaataata agtagactaa agtctaaagg taaaacaata
    36661 gtctatattt ctcacatatt agaggaagtt tttaaagtat gtgatagtgc aagtataatg
    36721 aaaaatggaa ttatgattgg aacttatgat gtagaggatt taactaaatt aaagataact
    36781 caacttatga caggaaatga taatcacaaa cttattgaga agaaggatta tacatttgca
    36841 aaatatgaag agccaccagt actagaagta aagaatataa gctggtctaa caaaataaaa
    36901 aatgtttcat ttaaagttta tagaggcgaa gttgtaggtc ttgcaggtct tgtaggttca
    36961 agaagaactg aaattataaa tttgatattt ggtatagata ataaagatag tggagacatt
    37021 tttatcaatg gtaaaaaagt agacataact tctcctaagg ttgctataaa aaacaaaata
    37081 ggattgattc ctgaagatag aaaaaatcta ggattaattt tagaacaagc tatatacaca
    37141 aactcatcat cagtacaaat tgataaattc aagaaattct tgtttataga tagaaataaa
    37201 gaaattgagt tttctaaaaa aggtgttaag gaattaggaa taaaagttaa tgatgtaaag
    37261 caagaagtaa aagagcttag tggtggaaat caacaaaaag tagtagtttc taagtggtta
    37321 gagaaagatt tagatttaat aatatatgat gagccgacaa agggaataga tattgctgca
    37381 aaagaagata ttttcaatac aatcaaagaa ttttcaagta aaggaatagg agtaatattt
    37441 atatcttctg atttagaaga agtaataaga gtaagtgata gaattttagt aactagagaa
    37501 ggttctattg tagatgattt aaaaaatgag aatatacagg ttcaagatat aatgaacagt
    37561 atatttaatg tataaaaaat gaaaatggag gactgaaatg aagaaagctt ttgagaagtt
    37621 aaatttaaga gattatggag tattattagg ttttttagct ttatgtatag ctataagtat
    37681 tgcaactcca tcatttttag gtaaacaaaa tatacttaat cttttacgac aatcttctat
    37741 aattggaata atttcagcag gtatgacttt tgttataata tctggaaact ttgatatatc
    37801 agttggagca gtagcagctc ttgcaggtgc tataacaatg aaatttgcga ctggtggaac
    37861 taatttgttt gcatccatgc tcttaggtgt agcgatttgt gcagtaatag gattaatcaa
    37921 tggtatagta gttgcaaaga taaatgtacc atcattaata gccactatgg ctatggtcac
    37981 tattgtaaga ggattgctgt tgatgcttac aggaggatat ccaattactg aaaatatacc
    38041 aatacttgat tacattggaa atggatattt gtttaatata ccaataccag tagtaatttt
    38101 ctttatagtg gtgttagctt catttattgt acttaataaa actaagtttg gtagatatgt
    38161 ttattctgta ggagggaatc aagaagcaag taaacttaat ggtataaatg tagattctca
    38221 caaagtgaaa gtatttatta ttaatgctgt acttgcagga atagctggaa tcgtactaac
    38281 aggaagactt gggactgcaa ctgcgattgc aggtgaagga tatgatatgg atgcaattgc
    38341 atctgtagta ataggaggta catcagtggc aggaggttct ggttctgtac ttaaaactgt
    38401 tataggagta ttacttatga gtgttataaa caacagtttt aatcttcttg gaatagatgt
    38461 atatttccag tacatattta aaggattaat aattttagca gcagttggat ttgattctta
    38521 tagcaagaaa aaacttgctt caagataaaa aataaggggg atttttttat gaaaaaatta
    38581 atgaaacatt tagcattgtt gctatcactt gttatgatat ttggtttagt tggttgttca
    38641 aatggtggtg acaaagaaaa aaatggagaa aagaaaatag cagtattact accaggttca
    38701 acaggttact ttgtagcaac taaacaaggt atagatgcaa aatctaaaga attaggtgta
    38761 agcgtggaat atgcagatgc tcaatgggat gctagtaaac aattatcaca agctgaagat
    38821 tttatggcta aaggggtaga catgattgca ttatgtggag ttgattctgc tgtaagtgag
    38881 agaatagtta aagctgctaa tgattcagac gttcctatag tagcatttac aaattctata
    38941 ggaagtaacc caactggaga atttaaaggt ttagttacat atataggaca aaatgaggaa
    39001 gaaacaggag cattaactgg aaaaattgct aaaaacttat taggagaaac tggtgggaaa
    39061 gctgtattaa tagaaggagt accaggaact actccacaag tattaagaaa aaaaggtctt
    39121 gaaaaagaat taaaagatag taatatagaa atagtttata atcaaacttc aaattgggag
    39181 aaagagcaag ctttaaaggt aacagaagat ttaattcaaa agaaaactga ttttaatgtt
    39241 ataatatgtc aagatgataa ttctgctaca ggtgcaggtc aagctttaaa agatgctggt
    39301 cttaaggata aagttaaagt cataggtttg ggtggaagta aagatggatt aaaagctata
    39361 actgatgggt taatagatgg tacaacttat atgtctgctg tagaagaagg tggattagtc
    39421 atagaaaagg catctaaatt ccttaaaggt gaaaaaatag aacctgttac acaaattaaa
    39481 caagttgaag ttaacaaaga taatatttca gagttcaagg gtgaatggta aattgtcata
    39541 gataataaat aagattttta gagttacttt agaaactata taaagtaact ctttttttaa
    39601 tttaatttag tgataaatta ttgaatagta tttctaaaca aataaaaaat taatataaac
    39661 aaagacttaa ttatactaaa ttataagtaa aactaatata aacttatgga aaaaaggaaa
    39721 acgtctaaag tattggaatt actatagtgt aggtgtggta ttaaaaaaac ataaaaaaac
    39781 ataaaaaaat tgttgaaaaa aatatagaaa ttttgtataa ttaaagattt gaaaagtgcg
    39841 gtatacaaag ccaattcttt tgtatataat atatataaat tcagaaaaag gaagggatat
    39901 gtatggccag gcggttattt ttagaaagga ttggacttat atttttaggt tcagcaatat
    39961 tagcatttgg agtttataat ttttattatt taaacaacat aacagaaggt ggagtgttag
    40021 gtattttact actgttaaaa aatttattca atatacaacc agcaatagca aatgttgtaa
    40081 tagatggttt gctactttta gtaggatata aatttttcgg taaaaaattc cttatatatt
    40141 caatagtagc ttctataact ttttcagtgt tatatgactt atttgaagct ataggacctc
    40201 tagtaccaca atcacaaaat atgcttttat caactatttt ggcaggtgta actgttggaa
    40261 ctggtgtagg tatagtagta aaagcaggtt gtgcatcagg aggagacgat gctttagcat
    40321 tagtaatttc taagactaca tctttgaaca tagggcaagt ttatttagca acagatgtta
    40381 ttgtattgtt gttatcatta ttttatctat cagcgtttga tatcttttat tctttgattg
    40441 ctgttacaat tagtggcaag gtaattgatt ttatttatta tcatggtaaa agtttggata
    40501 tggatataag taatgatata gttccagaat gttaatataa attaaataac tttagatttt
    40561 attaggggtg gcagatttgc cacctttttt gtgtctaaat ctttatagaa agtataatcc
    40621 tatctaggtt tttgcaaatc tcaaatatag aattatgttg aaatgactgg gaatacgatt
    40681 gctagatgtg cattttaaaa acccaatttt atatttatga aatactaatc attaatggat
    40741 gtttcttaat cctatcttta tacctaaaat gataagataa atgaagtagc aatacaaaac
    40801 taaaatttgt aaaagagatt aaattaaatg gaggagctaa aatgttggat atagttatga
    40861 tagcattgtt attcatagga tttgtttcca tgaagttact tgctgattgg tgtgggaaac
    40921 aaactgaaaa aaaataatgt aatgtatgga gggattacct atgtggtttc tggcagttgt
    40981 aattataatg ttaataatat atttggtata tgcgcttatt aatcctgaaa aattttaaac
    41041 agtataaggc taataagtaa gttgaattgg ggggaacaat ttttatggtg cagatagtaa
    41101 tagtgttagc gatttttatg attttagtaa tacctatggg caagtattta tatcatatag
    41161 ctactaatca aaaaacattt ggagatagac tatttgataa agtggacaat tttatatata
    41221 aggtatgtag tatagataag aaaaaagaaa tgaactggaa acagtatgca ttagctttat
    41281 tatttacaaa tgcagttatg gtatttatag gatatatcat acttagaact caaagtatgc
    41341 atatttttaa tccaagtgga attaaaagta tggaacaagg actatcattt aatacaataa
    41401 taagttttat gacaaataca aatcttcaac attattcagg tgaatcagga ctttcatact
    41461 ttagtcagat gacagtgata atatatatga tgtttacatc agctgcaaca ggatatgcgg
    41521 ctgctatggc atttgtaaga ggtctagtcg gtaaaaagaa aacattggga aatttttatg
    41581 tagatttaat taggataaca acaagagtac ttttaccagg agctttaatt attgggctta
    41641 tattagttac acaaggagta ccacaaactt ttgctgggac agaaacagtg actactatag
    41701 aaggaaagct tcaagatata gctagaggtc ctgtggcagc tcttgaatca ataaaacatt
    41761 taggaacaaa tggtggtgga ttctttggtt caaattcatc acacccattt gaaaatccaa
    41821 caataatatc aaatatagta gaaatattat ctatgatgat attaccagga gcttgtgttg
    41881 ttgcatttgg tcacatgata aagaataaaa aacaaggttg ggttgtgttt ggcgcaatgt
    41941 caatcatatt tttaataggt ctagtagtgt gctttaaagc agaaagtgca ggaaatccta
    42001 ttttatcaca attagggctt aatcaaagta tgggaagtat ggaaggtaag gaagttagat
    42061 ttggtatagc acaatcatca ttattcacaa cagtgactac ttcctttacg acaggtacag
    42121 ttaataatat gcatgataca ctgactcctt taggaggatt agtaccactt ttaaatatga
    42181 tgctaaatgt agtatttggt ggtaaaggcg taggtctgat gaatatgttg atgtacgcta
    42241 taatagcagt attcttatgt ggattaatgg taggaagaac accagagttt ttaactaaga
    42301 aaatcgaagg aaaagaaatg aagcttattg ctttacttat tatattacat ccacttttaa
    42361 tactaatgtt ctctggtctt tcagtagcaa taccagcagg acttgaagga atttcaaatc
    42421 ctggattcca tggattatca caggtattgt atgagtttgc atcttcagca gccaataatg
    42481 gttcaggatt tgaaggtcta ggagataaca ctatgttttg gaatataaca acaggtatag
    42541 ttatgttctt tggaagatat gtgtctatta tagtactact agcaatatca agtttgttag
    42601 catctaaaaa agctgtaaat gaaagtatag gaacacttag aacggataat tttacattta
    42661 caatagtttt agtacttgtt gttttaattg ttggtgcttt aacatttttc ccagccttag
    42721 cgcttggacc tatttcggag catctagtgt tgtggcacta aaaaattggg agggagtaaa
    42781 gttttatgga aactaaaaaa acaaagttta ttacaaaaga tattttcaaa acttccatta
    42841 tagaagcttt taaaaaatta aatcctaaat atatgatgaa aaatccagtt atgtttgttg
    42901 tagaaattgg atttatagta acattgatac ttacaatagt acctagtttg tttggtgatg
    42961 aaggcaataa cttaagagct tataatggga ttgtaacaat aatcttattt ataacagtcc
    43021 tttttgcaaa ttttgctgaa gctgtagctg aaggaagagg taaagctcaa gcagatacac
    43081 ttaagaaaac tagaaaagat acagtagcaa gggttataga tacgttagga aatgaaaaaa
    43141 tgataagtgc aagtgagcta aaacttggtg atattgtttt agtaaatgct ggagaagtta
    43201 tcccaaatga tggagaagtt atagagggta tagcttctgt ggatgagtca gcaataactg
    43261 gagaatctgc acctgtcatg agagaatcag gtggagattt cgcatctgtt acaggtggta
    43321 ctacagttgt aagtgactgg ttaaagataa gaataacaac aaaaccagga gaatcgttct
    43381 tagataaaat gatagctctt gtagaaggtg cttcaagaca aaaaacgcca aatgagattg
    43441 ctttaaatac tttgttagta gggttaacac ttatatttat ggttgtttta atatctcttt
    43501 atccaatggc aaactatgca ggtgtaaaga ttccaatttc tactatgata gctctcttgg
    43561 tatgtttaat accaactact ataggtggat tgttgtcagc tattggtatt gcaggtatgg
    43621 atagagtaac tagatttaat gtaattgcaa tgtcaggaaa agcagtagaa gcttgtggag
    43681 acgttgatac tatgattttg gataagacag gtacgattac ttatgggaat agacttgcat
    43741 cagaatttat agcagttgga aatgcagatt caaaagattt aataaattat tctgttatgt
    43801 gttcattaaa agatgataca ccagaaggaa aatctatagt tgatttaggt atgaaattag
    43861 gttcaacagg taagacaaaa gaggcagagg aagctgagtt tgtagaattt tctgcacaaa
    43921 ctagaatgag tggtattaac ttagctgatg gtagagctat aagaaaaggt gcttatgata
    43981 gcataataaa aagagtaaaa gaatctggtg gtacagtgcc agaagattta gaagaaaatg
    44041 taaatcgagt agctaaacta ggagggacac ctttagtagt gtgtgtagat aatgagatat
    44101 atggaattat ctacttaaaa gatacagtaa aatcagggct tgtagaaaga tttgctagac
    44161 ttcgagagat aggaataaag acaataatgt gtacagggga taatcccttg acagcagcta
    44221 caattgcaag agaagctgga gtagatggat ttattgcaga atgtaaacca gaagataaaa
    44281 tagatgcaat aaaaaaagaa caattagagg gtaaaatagt tgcaatgaca ggtgatggaa
    44341 caaatgatgc tcctgcactt gctcaggcag atgtaggtct tgcaatgaat agtggtacaa
    44401 catctgcaaa agaagcagca aatatggtgg atttagattc agacccaact aagatattgg
    44461 aagttgttga aataggaaaa cagcttttaa taactcgtgg ggctttgaca acatttagta
    44521 tagcaaatga tgttgcaaaa tattttgcga ttataccagc tatatttact cttgcaatac
    44581 ctcaaatgga gatattaaat gtaatgaaac tttctacgtc atttagtgcg atattatcag
    44641 ctttaatatt taatgctata attatcccat gtttaatacc tcttgcaatg aagggagtaa
    44701 aatatagacc tatgaaatca caagctatgt taatgagaaa tatgcttata tttggtcttg
    44761 gtggagttat agtaccattt ttaggaataa aattaattga tttattgatt acacctttag
    44821 taatggttct taatttaggt taataaatgg aggatataaa aatgaaaaca ttaaagccag
    44881 cattacttgt aagtattgta ttgttagttg tttgtggact tgtatatcca cttgttttga
    44941 caggtgtaag ccaagttgca tttaaagata aagctaatgg aagtatgata gaagtaaatg
    45001 gtgtaaaagt aggttcagaa cttattggtc aaagctttac agatgcgaga ttctttaagg
    45061 gaagagtatc atcagtaaac tataatactt atacaaaaga agatttagta ccagataaag
    45121 atggaaacac atcttatgga ggtgtatcat cagggtcttt taattatgga gctacaaatc
    45181 cagaacttca tgatagagta caaaaagata tagaacagtt tttaaaggat aatccaactg
    45241 tcaaaagaga ggatatacca acagatttac ttacagcatc aggttcagga cttgacccta
    45301 atataagtcc agcctctgca aaaattcaga taccagctat agcaaaagcg tctggaatat
    45361 cagaaagtaa attacaaaaa attgtagaag ataatacttc caaaaaactt tttggagttt
    45421 taggtgaaga tagagttaat gtattaaagg ttaatgtaga ggtcgcaaaa atattaggtc
    45481 ttatatagta ttttgtggaa ttttagcaac aaaatattac tcaagattta atttaaaggt
    45541 taaattttaa agagtgaaaa tcgataatga ttttcacttt tttatttgaa tattactaat
    45601 atttggaata aagtgattgt aagtataaaa tccaaaaaaa ggttgcatta tcaaaatgat
    45661 aatactataa tatatttatc gttatcaatt tgataataga tttggacata taggaggaaa
    45721 tagtatgtta tataataacg cattagagtt gataggaaac acacctgtag taaggctgaa
    45781 taatttaggc tgtactaatg ggtgttctaa catatatgta aaattagaaa aagtaaatcc
    45841 agcaggaagt ataaaagata gagctgttta tgaaatgtta gagggtttag agcaaagagg
    45901 agaattaaaa aagggagatg tactagttga agcaactagt ggaaatactg gtattgcatt
    45961 atctatgata ggaaaattaa aaggatatga agtagtaatc gtaatgcccg aaacaatgag
    46021 cgttgagaga agagatttaa tgaaggctta tggagcaaat ttggtgctta cagatggtaa
    46081 agctggaatg gcaggttcca tagaaaaagc aaatgaactt ttaaaagaaa atccaaacta
    46141 taaaagctta aaacaatttg aaaataaaga taatccaaat gcacattata aaacaacagc
    46201 agttgaaatt atgaatgatg tcaaagattt agatatattc gtatgtggag ttggaacagg
    46261 tggtacttta ataggaactg caagatattt aaaagaacaa aatccaaata taagagtaat
    46321 tgcacttgaa ccaaaaaaat ctccagctat atcagaaaac aagactggac ctcataaaat
    46381 acaaggaata ggtgctaact ttgttcctga aaattatgat tctagtgtag ttgatgaagt
    46441 aatattagta gatgatgaag atgcatttga tacagttaaa ttacttgcag caaaagaggg
    46501 aattttagta gggatatctt ctggagcaaa tatatttggt gctatagaga tggcaaaaaa
    46561 gtatccagat aaaaagatag ttacagtagc tccagatgga gttgataagt atatgtctat
    46621 gggaatattt taataatttt atttgaggga gtgaatactt tgtttaagaa aataaataaa
    46681 gatattgaat atataatgaa gaatgatcca gcagctaggt ctaagataga agttttttta
    46741 ctttatccat cagttcatgc aatgataatg cataggatgg ctcatgctct ttataagaag
    46801 aagaagcttt ttacagcaag attaatatcc cagatatcca gatttatgac tggcatagaa
    46861 atacatcctg gtgctaaaat gggggaaggt atattgatag accatggaat gggtgttgta
    46921 attggagaga cagctgaagt aggtaatagg gtgacaatat atcaaggagc tactttagga
    46981 gctacaggaa aagatactgg aaagagacat ccaactgttg gtgatgatgt attaattggt
    47041 gctggaacaa aaatactagg acctttaaat ataggttcaa attcaaaaat tggtgcaaat
    47101 tctgttgtcg ttaaggatgt acctaatggt gcaacagttg ttggtatacc agcaaaaata
    47161 gtaaaaataa gaaacctaga acctgtaaaa aagaataaaa aagaagtgtc ctatgagtat
    47221 gatgaattag ataatgtata ttatatatag gatttatata actataaaat aaactttata
    47281 aaaattattt taaaaggtat ttttttcaaa tttgaggaca taataaaaaa gaactgaatg
    47341 ttacagtttt ggttcatcaa tctttgataa acaagatttt aaatttgtag cgtctaggag
    47401 gattttatta tgaaagcaaa tgttaatcaa gatacttgta taggttgtgg attatgtcca
    47461 tcaatatgtc cagaagtatt tgatatgaag gatgatggga aatcacatgt tatagttgat
    47521 gaagtaccaa gtgatgctga agaatcagca gcagaagcta gagaaagctg tccagttgat
    47581 gcaatagatg tgcattaata aaataaatgc ctataaaaat tgaattttca atttttatag
    47641 gcatttgtct tttattcagt tagtatttca acacctgttt ctgtaactaa aaccatacat
    47701 tcccattgag cagataattt accatctttt gtataaatag tccaattatt ttcttcatca
    47761 acaaaaattt cgtgagttcc ttcatttacc ataggttcta ttgtgaatat catcccagga
    47821 accaatagca tctcagtccc ttttttagat acataactta caaaagggtc ttcatgaaag
    47881 cttaatccaa ctccatgacc acctatttct ctaacaacag agtatccatt tttctttgca
    47941 taagagttga taacatcacc tatatctcct aagaatcccc atggtttggc aacttcaaga
    48001 cctttttgga cacattcctt tgtaacttga actaattttt ttgcattttc gttaacatta
    48061 cctatcataa acattcttga agcatctgaa tagtatccgt taaaaatagt agaaacatct
    48121 acatttataa tatctccatc ttttaagata atgtctttac ttggaatacc atgacaaact
    48181 tcattattta ctgatgtaca tacactttta ggaaatccat tatagtctag tggagcaggg
    48241 atagctccat tttgtagtgt aaagtcatga accaacttat ttatatcttc tgtagacatt
    48301 ccaatttcga ttttatctga aatataatcc aaaatttttg tgtttattac agcacttttt
    48361 tttatttcct caatttgact ttcatttttt ataatatcat gagttggtac aatatgacct
    48421 aacttagcaa atgaatctat tttattatcc atatccatat gacatttttt atatttttta
    48481 gtacttccac accaacagct atcatttcta tttaacttca taacttttca tccttctttt
    48541 attatttatt taaattatgg gttacataaa ctattttaaa acataaccat tataaatatt
    48601 ataacataaa tactaagaaa tcctttatag atagtgattt attcaaagta taaattatta
    48661 tatggttatt gttgatgaaa agaggatagt taaatgtatt attggatatt agcgcactta
    48721 atagtttagt tcaagttttt caagaaaatc atatgttaga ggacaatttt cctttaaagt
    48781 attttttgaa tcttcatcaa gataataatg tacaaatgat tctgcaaaaa attcttctat
    48841 aaacttgctt atatatgcat gtgcaacttg cttagggtca taaagcttat atctttcctg
    48901 agcaaatact tccataaatt cttcagaatt tgatttttta tttaaaacat ttttatctat
    48961 agcatgtgca gtttcatgta attctaaatt ttttgatgaa tgtacatttg catagctagg
    49021 gttactataa cctattttag ccactataga attatttcta tatataccag gtacatcttt
    49081 ccaagtcttg cctgatctta cccaacatgg aggtaattga tattttaaat cactaaattc
    49141 tggttcatca gttagatttg aatttattaa ttttattttt atatcctttt ctttaagtgt
    49201 ctgtaaatat ttaatattta tttttgcaag tctgtttttc atattttcaa cttcatcttt
    49261 atcataattc aagtcatcag gaagtataag catttgttca attatatcta tactactgtc
    49321 ttttatattt tcagattctt catcaaattt atattgaaga gtattatttt catagatagt
    49381 tatatttgta ttattttcta tagaataaga gtgaatatcc tctaaatcta aaatattcat
    49441 ttgttgtaaa atatgttttg tttcgccact ccacactact aaagaaagtg aattaaaatt
    49501 aattagtgga ttttcttttg cttttatatc attgcttata tctacatcaa atacatattc
    49561 aattgagtct tctatgttaa gactatctgt attcttttta atatataaat acgcttgttt
    49621 taagtctata taaatctcat ctaaagattc gtcataaaat tctgataaat tattagtaaa
    49681 gagttcttca cttaaaagtt catttttatc agttatactt tcaattaaaa tattaatttc
    49741 ttttatcata ttgtaaatac ttatttttct atttgctttt tcactagata cattgcatgg
    49801 cgcaagagca atgcaataaa aatctttttc ttttttataa aaggctttaa gtgattttga
    49861 taaaagtgta aagtctacac ctatctgtaa gttgacctta agtgagtcat tttgtaataa
    49921 ttcagtatta tttcttttag ctgtatttaa attgttttcc ataatcattg cccccttttt
    49981 attagggtat cataattttt ttatatgtgt caatttgttt ttttgaaaat tataattttt
    50041 ttgaaaattt tattttttat aatttgtgaa ttttttatta tagaaataaa tatgttatta
    50101 ttatgtcaaa atttagcatt agattcatgt agagtatgtt ttatacatat attataatta
    50161 attctttgaa gattgcatat tcaaaataca caccattttt tttaattcta taatataata
    50221 tttatatatt taatgttagg atgtgattta aggtgtattt tacatatatt ataagatgta
    50281 aagatgattc tctatacact ggatatacca gtaatatagt tagaagaatg aatgaacata
    50341 aattaggaat taattcaaaa tacacaagag caaagggatt tgaaaaacta gaagtttatt
    50401 ttgtgaccaa cacaaaaagc aatgctatga agttagaata ttatataaaa aaattaacta
    50461 gaaataaaaa attgtctata ataaaaaacc caagtatact tataaattta attgataata
    50521 aagaagatta tattattggt aaggaaatag aacaattaac ataaatattt atagtaacat
    50581 tataatgggt gcatatggtg taaaaacttg acaataaata ctattgtaat ataatgaagt
    50641 tataaatata gtaaattaaa atagctaggg gagccaagag ctgagaggta taccgaccct
    50701 tacacctgat ctggataata ccagcgtagg aaagcttagt aaaaattcaa gtatgtatta
    50761 tttgtgatat atgctatttc taagctatac ctattgtagg tatagctttt ttaattaagt
    50821 tatttaaatt aaactttagg aggcaacaat gagtaattat aaaataccaa cacttacaat
    50881 agccggctct gattcatctg gaggagctgg gattcaggct gatttgaaaa cgtttagtgc
    50941 aattggtact tatggtatga gtgtaataac agctataaca gcacagaata ctaaaggagt
    51001 ttttgctgta gaggatttaa ataagaaaat aataaaaaaa caaatagagg cagtctttga
    51061 agatatacct ccaagagctg taaaaatagg aatggtttca agtcctgaga ttatacttga
    51121 aatagttgag aatctaaaga aatacaatcc aaaatatttg gttgtggacc cagtaatgat
    51181 atctaaaagt ggatattatc tattaaagcc agaggcaaaa gaaaacttaa ttaagtattt
    51241 gataccactt gcatacataa ttacaccaaa tataccagag gcagaagaaa taacaggaat
    51301 aaaaatacat aatgtagatg atatgaagag agtaggagaa gaaatactac aacttggacc
    51361 taaatttgta cttatgaaag ggggtcattt agatggagaa gcagtggata ttttagttgg
    51421 taaaaatata tttaaagttt ataaaagtga aagaattgat aaaaaaaata cacatggaac
    51481 agggtgcaca ttatcttctg caataacatc ttatctagca ttaggatatg aaataacaga
    51541 agcagtaaat ctaagtaaaa tctatataac agaagcaata aaaagaagtt ttgatatagg
    51601 tcatggagta ggaccagtac atcattttta taaatttgag taataaaaaa atattggagg
    51661 tagaatatgt ataatttaat taaagatgta aaaaaattaa atccattggt aattcattat
    51721 actaataatg taactataaa tgattgtgct aatgtaactt tagctgtagg agcaagtcct
    51781 cttatgagtt tttcatatga ggaagtagaa gaaatggtaa gtgtagcaaa ctctgtagta
    51841 ataaatatag gaactatgaa ctcaaatatg ttggatttat tcctattagc tggaaaagca
    51901 gcaaataagt acaataaacc tgttgttttg gacccagttg gagtatttgc aagcaaagcg
    51961 agagcagaac ttacaagtag acttttaaat gaagtcaaat ttagtgttgt taaagggaat
    52021 gtatcagaaa taaagtttat aggtggcttt aatgtaaggg gtaaaggtgt agattcattt
    52081 gatgaagaag aagattctac tgagataata agaaagattg ctgaaaagct tgaatgtgta
    52141 gttgtagcaa ctggaaaaat agatataata actaatggta aaggtacata taaaataaac
    52201 aatggaactg ataaattaaa aggaattaca ggaactggat gtatgactgc tagcttgatt
    52261 gcaagtttta tggctgttac tgagaatata ttagaagcag caacaatggg tgttcttaca
    52321 atgtctttaa gtggggaatt agctaattta aataatccac caataggtac atttaaagaa
    52381 aatcttatga atgctattta tcaaatggat atagatactt taagtaaaaa ttctaatatt
    52441 gaatttttaa attaataaag agtaagggag acttaaaatg attgataaag aatctttaaa
    52501 aaaatgttta aagttgtatt tagtaactga ctctgaaatg cttaaaggta gagactttta
    52561 taaatgtctt gaagatgcaa tatcttctgg aataacaact gtacaactta gagaaaaaaa
    52621 tgcttctgga agagagtttt taagaaaagc tatgaaactt agagaaataa ctaaacaata
    52681 tggtgttaag tttataataa atgatagagt ggatatagca cttatttgtg atgcagatgg
    52741 agtacatgta ggacagagtg acattgatgt tagagaggtt agaaagctta taggaaacaa
    52801 taaaattcta ggagtatcag caagaacttt agaagaagct atttgtgcaa aaaatgatgg
    52861 cgcagactat ttaggtgtag ggtctatatt cacaacatct actaaattag atgcaaaatc
    52921 agcttcgttt gaaactgtta aagaaattaa agaaaaagta gacatgccat ttgtactaat
    52981 tggaggtata aatttagaca atatagataa acttaaatgt ttagaaagtg acgggtatgc
    53041 tataatatca gctatattaa aagctgaaga tatctctaaa gaagtggaaa agtggacatt
    53101 aaaaatataa aattggctct ggtagtgaaa aaaatggaaa aatttgatat aatctaagag
    53161 taaaatttaa gcaattataa atgataaact tttctacata tactttttaa tcaagatata
    53221 tgtagatttg gttaaaaagg agctataaat gattaggata ttgttagtgt gtgttggagg
    53281 catgtcttct accctattgg taaataaaat ggagaaggat gcaaaaaaaa gaaatataga
    53341 ctgtaaaata tgggcagttg gagaaggaga tataaaatcg gagcttgata actttgatat
    53401 tttacttctt ggaccacaac ttagatttat gcttgatgac gtaaagtcta tagttggaga
    53461 tagagctcca gtatctataa tagatatggt aaactatggc acttgtaatg gtcatgctgt
    53521 gttaaattcg gttttagaaa tattaaaata aataataaaa gtggattcta tataatagag
    53581 tccattttta ttatttgtta ttaataggct taaaacttag cttaccattt ctttttttaa
    53641 tctccacata gcaagtgaaa aacttgaaca gcacaatatt aaaaatagta ggataacagg
    53701 cagtatatct ccaataagaa tagtctcacc aaatattaag ctacgtaaag cgttaataac
    53761 atgggtaaat ggattgagca tcactgctac ttttaatcct ccagataaac tttctatagg
    53821 gaaaagagct gaacttaaaa agaaaatagg aagtacaatt gcagtcataa ttgtttcata
    53881 aactatttca tttggcaata ataaacttat agaataagct agacttgata aaaagaaggc
    53941 tgtcataaat atcagtacta tcataagtag gattccacca atgccagatt ctatccttac
    54001 tgagaagaat atacttacta tacacaaaat agttacttct atgaaagaaa ctaagatagc
    54061 ttctaataat tgaccaagga cgattgaata cctactgata ggtgcaatta agactctata
    54121 gaaacttcca ctgttcttca ttataaagtt tataatacca ccactactac aagaagaaaa
    54181 cacaaccagt acaatgatac ctggtagtat aaaagcagta taattattga tatttatatt
    54241 attcatagtt tggtttgcaa tagaactata aagcacaagc caaagaaaag gttgtaatat
    54301 agtaactaca aatgagattg gatttttaaa acgccacttc atactacgcc ataagatatt
    54361 taacattccc attcctcctt taagcttttt ttagaacttg taagtgctaa aaatacatct
    54421 tcgagacttg gctctacaat ttctattgca tcaaattcta tatcatgttc taaaagccat
    54481 ttatttatta aagtaaaagc agttctacta tcgtttacac ttataaaaat tgaattttct
    54541 cgtacgctca taaactttac taaaccagta cttttaattg aatctttata tttttttata
    54601 tcttcagtat tatgaaaagt tatacgtagt atattttgtc taatgtaact acgtaaactt
    54661 gatggtgttc cttgtgctaa atcctttcca ttcttcataa tacaaatatt atcactcaat
    54721 tgttcagctt cttcaagata atgagtagtt agaaatatag ttgtgccata ctcatctcta
    54781 atttttaata acatatccca catagatttt cttgaatcga catccatacc aacagttggt
    54841 tcatctaaaa ataggatttt aggagatgat accatattca tagctatgtc caatctacgt
    54901 tttacacccc ctgaatatga tgaagtagga tattttaagt aactagataa gtcaaactta
    54961 tcaattaaag agtctattct ttgttttgca atctgtggtt ctactttata cattttactt
    55021 tgaaatacca tattttccat aagggataaa tgttcatcaa tagagatttg ctgtgctaca
    55081 caagcaattt gagtacgtat ccaagaagga ttatctacta aatcttttcc aaacattgtt
    55141 acatttccag atgtaggttt gtaaaaggta gtcaaaatat ttataagaga agatttacca
    55201 gcaccattag gaccaagtaa agaaaaaatt tctccagcat ttacattaaa gcttagacca
    55261 tttaaagctt tcacaccatt tttatattct tttactaaat tgtctatttc aatcgctaac
    55321 atatattatt cctcctcttt aagtggaaat attatctctg taatatagtt atctgggttt
    55381 ccttttatca acatacctgg tcctttaata aatacttctc tccaaggagt ttgtattttt
    55441 atattatttt catgaatata tttaaatatc atttcatacg tttttggcaa attactataa
    55501 gagcctgtgt gagtaaaaaa taaagctttt gttttaggaa attcttttgt agttataccc
    55561 atacgatttg gagtttcagc agttggaaca cataattcca tttctgcaac accagttttt
    55621 tggtcaacat catagtagca aaagaatggt gcaccgttag actttccttt tatagcttta
    55681 aatacatttg gaaaatactt tgttgcctca gtcataggtc cattataacg catggtagcc
    55741 actgtgactg attcgatatt tttgatttca attttgcaat tcatttgttt acctcctaat
    55801 gtgtgttcat attcttacta gatttttaag cattaataca tataagattt tgattagttg
    55861 aaaacatata atcttatctc gtttgcttgt tttcaagtct aacataacat aaaatatata
    55921 tcctctcatt tgatgctcca ttttgtaaag ttattattta agctttactt tagatttttt
    55981 agcaaattaa aataaagcaa tttataaaat aagtatttac aaattaagtg tattaatcgt
    56041 ataatacact taataggata ctagataaag tctgaaataa aggcgtattt ttttaaagta
    56101 agtgtactat cgtattaata cactagaata ggaggaatca tgaattttga attagataat
    56161 acaactccca tttatttgca aatagtaaag tatataaaga gacaaatagt aacaggagag
    56221 ttgaaaccag gagagacaat accatcaaga agagaaatgg cacttaatct aaaagtaaac
    56281 ttaaatacag ttcaaagagc atataaggag atgggtgata tgaatataat aaatactttt
    56341 aaaaattatc aaagcagtgt aacagttgat gaaaatatat taaaaaattt aaaattagag
    56401 cttataaatg aatcactatc tgtttttata gaagatatga aagcaataaa tgttagcaaa
    56461 gaagaagttt taaaaataat agaagataag tattagtttt ttaacaaata gaaaacttag
    56521 tttagaaagt ttatttataa gcatattgga tgtggaggat agtaaatatg atagaaataa
    56581 agaatgtcag caaaacatat aaaaggatgc aagggcttaa aataagaaag atagaagctt
    56641 taaaaaatgt aagttttaat atagaaaagg gaaaaataac tgcattactt ggtataaatg
    56701 gtgttggtaa atcaactatg ttaaaagcaa tagcaggact tataaacatt gatagtggag
    56761 aaattcgtat agatggagaa aaaataaatg aaaaagtata caataaattg gcttttgttc
    56821 cagatgtaca atctcacttt agcaatacaa caataaaaga aacatttgaa tttatggaaa
    56881 ttttttattc aaagtggaat aaagaaaaat caaaagaaat gatggacata tttaaattgg
    56941 atgaagatga aataattgat aacttgtcaa aaggaaacat tgcaagagta aaattaatac
    57001 ttggattttg ccaagaccca gagtacatac ttcttgatga accatttaca ggaattgatt
    57061 tgtttaagag ggaagagttt ataggagtaa tagcgcaata tatggaggaa aatcaagcca
    57121 ttatcataac tactcatgag atagtagaga tagaaagttt agttgatgag gttgtaattc
    57181 ttgatgaagg gcagattata acttcattta atgcagaaga attaagagaa agagaaggta
    57241 aatctatatt agataagatg agggaggtat ataagaatga ataaacttct atatctaata
    57301 aatgtagatt tgagaagaag caataagttt tatatagctt atatatcatt tttttcatta
    57361 attacactta gtttaaattt attcgaaatt aataaattta aaaattctaa atttattatg
    57421 aacttagcaa tagaagattt tggaggtata ttttatggac tagggatact tagtaatctt
    57481 ggttttatcc aaagtatatt gttctttggg atattgggac tttttatata ctatgttttt
    57541 atgtggaaaa gagagttctt ttcaaataat caaagtattt atacacttat gatgttacct
    57601 caaaataagt ttaagatttg tatatctaaa tcaatagcct tgataacaat gatatatggt
    57661 tttttgataa gtcagacagc aacattattt atatgtaaat atatatttaa tttcattttt
    57721 agaaatatgc ctataatcaa tatgaacttt gccaaagatt tatattattt aaacttgaag
    57781 agtataccaa ttgattttat ctcttttatg gctatttatg tatttttact acttatagct
    57841 atttctattg taaattgctg tatattattt atcttttcct atataaataa attttatgta
    57901 attttaatca ctttgctgat tatagcaggc ttatattttt caacaatata tataaatata
    57961 atcactttat ttagaaaata ttataatctt ataggatttc aatttaacaa tttagtagca
    58021 gggttattaa gttttttaat tataatgttt attctaaatg gaatatctta tttgctaatt
    58081 aaaaagaaag tatctcttta aggaggggtg gtatgaaatt aaaatctaaa atatctatac
    58141 ttattatatt tttgacttta gcaatatatt ttagtatagg tttattaaat aatgaagata
    58201 atttaaagat aaaaactata aaaggtgact ctaatgaatt agaccatata aacataaatt
    58261 ttggatatgc tttgaatgga tatataaatt catattatac aataaatgga agcaacaaaa
    58321 ctaaaaagac tgaattaata aaactacaaa aggatagtaa gaacacaaat aatttaattg
    58381 atgtatctag tggttcagat ttaattgctc atgttggatt tgaaatgaat gaggagtcaa
    58441 aagatataaa ctttgtgata gatgagaaaa aagaagattt agaaaaaggt gtatttccat
    58501 cagaagatag tgataaagaa attgaatatg aaaaattaga tatgaataat tttacaagga
    58561 caagatataa agtagataaa agtacagatg attattatgc aaagatacta tcatcaaaaa
    58621 gatataaaaa atacttatat gtatctgtac tttatgctac aagtgattca tcagaaaata
    58681 acaaagaata ttcaagtact atagatataa taaaaattaa tccagaaaat aaaaaaatca
    58741 agactataaa aagtataaat ttaagtaatt atttttccga aaaataccaa aacatagaga
    58801 acataggtgt aagttatgct agcaaatatg aggataagat gtatatttta gtaaatgtac
    58861 taaatacaaa cataggtgat aatagtaatt ctaaatttca tttacttgag tataatcttg
    58921 aagaaaataa ggaaagcata atggaattaa aaactgatag caaaatggct ttagcaaaag
    58981 caaagttaga agctaataaa ttatatatgg taatgtcgaa tgattatgat aatagttcaa
    59041 ttacagagtt aaatttactt acctataata tattagataa aagcttagat gaagataaat
    59101 atgttttaga taatagagaa aaaagaggaa ttagaagtat tgaaattgat tcaaataaaa
    59161 tcgttgcata tacatcaagg ctaaactcta tattatcttg ggatgataaa tttatgctat
    59221 atataataaa taaaaattct aaggaaattg tatatgaagg agaattacaa tttaacagtt
    59281 caaatagtat gttagaattt gaaataaagt aggtgagttg atgaaagatt taataagatt
    59341 attcgaattt gaattaaaaa gaaatataaa gaattatata tttataataa tttgttgttg
    59401 ttcttttgta attttaaaca tagtaaaaaa tttaaatgac tataattaca taatagaaaa
    59461 tgcagttaaa agtgaacagt taacaaaaat cggaaatacg atagaaacgg taaatgttac
    59521 aggtttctca agctttagaa atataatggg ttctacagaa ttgtggttta tgtttggtat
    59581 aattgcatgt atttgctatg ctttttttat ttggtataga gactttaatg gtagaagtaa
    59641 atctatatat acacttataa tgctacctaa aaatagaatc aatatttata tatctaaatt
    59701 attaaatata ttatttctag tgtatagcta tacagtagta cttacaatat ctttgtttat
    59761 tgcaagtaag ttgttaccta gacatatgct tggtaatgtc acaaactatg gttttgtaca
    59821 agaaacaata tatgagttaa aaatgttact tccatatagc tttgaaatac tatttgtaga
    59881 gtatatattt ttattgatag gatttgtatc tgtagtattt acatcaattc ttataaataa
    59941 atctatttat aaagtaagca ctttaataag ttttctattt ttagttatag aaattttagt
    60001 gtttataatt tctatagaat ttattatacc ttacgaatac agtgatgtat ttactgttct
    60061 atattcaagt ataaacatat ttgtatgtag tcttatatct aataaacttt tgaagcaaaa
    60121 gattgacttt taggagggat attatgaaag caaaaaatat aggaaaatat acaatatgtt
    60181 ttataatagt atgtttttta atgattacta tgaccttaat attgagttat tttaataagg
    60241 ataaactatc tgtaaaaact ttaaaaggca atgtaaaaga tatagggaga gtaagtgtag
    60301 tatatacacc taatataagc aaattttctt atgaggaggt aattataagt aaaaatggag
    60361 taagaaataa tacaaaccca aaatcaagaa ttagaaatga ttatttaaat attgacaaaa
    60421 aatacagtga ctttgttaat gataaaggaa aagaatttat atataaagat gatttgaata
    60481 taggagaagc gtatacctct gttaagtctg atttagtaca aggaatgaat gctttaaatg
    60541 attgtataaa ggtttcaaat aaaaatttaa aaagtggggt agaagaaaat tttgatatta
    60601 atttaaataa gtctgatttt aaagaaaata gttggaaaac cttatttaac aaaatatata
    60661 aaggtaattt atatatggta attagtgaaa ctaatatttc aggttctaaa gtcaataata
    60721 tttgtatatt aaagatagat ataaaaaata agtcttataa attattaaat agatttaatt
    60781 taggattaca gaatggagaa caacaaaata tcaatgaaat taaattttct attggaagta
    60841 aattatactt agaaatagta aataataaaa gtaaaaatgg atatattgaa ggacatgata
    60901 gttactctaa ctttattata tatgatatag aagataacac ttttaatata agtaataaat
    60961 ttatggataa tctaaacaaa gaaaagaatg caaatccaaa ggagattggc ttattaagta
    61021 aaactaagct agattatatg gtaaaaaaca ataaattgaa tcttatagtt acggatatga
    61081 gtaattccat aactaatctt gtttatgata ttaattctaa tgagattaaa ttagaagatt
    61141 atgagatact tgatttaaaa gtagattata atgaagcatc atctggagtt aggaaagtta
    61201 agctactgga tgataagata tattctattt caggtattaa gaacagtata tcaggagaat
    61261 taaaaggatt taaagggatt gttgatgtag tcggaactaa gccagtaaaa tttcaagtat
    61321 ttgatatgaa acttaaaaag aatatttatg aagctgagct aataaatgga gatataagtt
    61381 tacaagaaaa gttatttttt gttgcaaatt aagtgttaga attaatttta gaactttaaa
    61441 cttttatatg tatcacagat aagtataagt aagggagtgt ctcaaaataa actttttagc
    61501 tcatgagaca ctttttttat atgaaatcaa atatattttc attgtttaga tttattttga
    61561 taatgaaaaa aagattatct ttattttaag aaagacattt atttataatt atatacaaaa
    61621 atatttttta atgtttttgt gtataattat aacaatttaa tttatattaa tgcacttaaa
    61681 tttgaaatag aatgcttata gtggtaaaat taattattag aatattagaa ataataaata
    61741 aataatacat tgtacttaaa agggggagaa atttaagatg aacaaaaaat atattaaagc
    61801 agggaattta attgatggaa ccggaaatag tattatgcaa aataagggta taattattga
    61861 tggagatact atagttgaaa ttgaagatat aagagatgat ttaaatggat atgatgtgta
    61921 cgattactta gataaaactg ttatgccagg cattatgaat tgtcatgttc acttgacaat
    61981 ggagccagtt ggaaatccaa agatatatta tgataatgta tcagatgtag agcttgtagt
    62041 aaatacgata aaacaacttg atgcttattt ggattcagga gtaacatata ttagaagctt
    62101 aggttgtccc aaatatgtgg atgtacaact taaaaatctt atagacaaag ggtctataga
    62161 tggtcctggt atagttactt caggtccagt tatatgtatg acaggagggc atggatatta
    62221 ttttggtatt gaaagtgatg gagtggatga atgtagaaaa tcagccagaa cagttttaaa
    62281 aaatggagta gattgtgtaa agataatggc aactggaggt gtaacaactg atggagttga
    62341 gccagggtca ccacaattaa ctttggagga aatgaaggct gctgtagatg aagctataaa
    62401 agcaggtaaa ataactgcca cacatgcaca aggaagaact ggtataaaaa atgcagtgct
    62461 tgcaggaatt acttctatag aacatggtgt ttatttagat gatgaaataa ttgatttgat
    62521 gcttgaaaga ggaacttact tagttccaac tgtggctgca ccatatttta ttctaaatgc
    62581 aggaaaagaa agtggaataa ctgaagctac tcttagaaag tgtgagattg ttgccattcc
    62641 acataaagag tcattcctaa aagcatataa aaaaggaatt aaaattgcag ttggttctga
    62701 tgcaggaact tcttataatg aacatggaaa aacatattat gaaatgaaac taatgtcaga
    62761 ttatggtatg gataatatgg atataatagt tgctgctaca aaaacagcat ctgaactttt
    62821 aagaattgat aaaaattatg gaactctaga aaaaggaaag aaagcagatg ttatagttgt
    62881 aaatggaaat ccagtagaga atatagacgt acttgcagat gtgttagcag tatttaaact
    62941 tggtaaaaaa gttagataaa tagtataaaa ataaaaaaga gtgtctaaag aaatttttaa
    63001 ataattatag acactctttt ttattagtaa taattaaatc ttttatactt tagaaaatag
    63061 attctatttt atatttagat ataactcttt aaaatcattc ttatgcaata taatctatag
    63121 aatctacaca tacaaagtat attcttgaat cattagaatt tccaagtact ataacatcat
    63181 ttttcttacc tagaacttca acaccagtta gaaccaaact accagctact acagtaactt
    63241 gattatttat atttgacata taaagattat ctaggatacc tttattacaa cagcaatcat
    63301 cacaatcgca gttgcaatta cattctttgt aatgtttttt atcaagatag taacctaaag
    63361 atgctatgaa atcttcataa tctgcaggtg taatatcaaa tgcaacagct ttaagattac
    63421 acaatgatgc taaatctacg tttgctaatg gagtagatgc agcaagtata aaatcaatta
    63481 tagcagcaag tattgcatct aatatagccc caaggtctat cgtaggagga ataactgcat
    63541 caataagtgc aattaattca gctactcctg gtatagttcc tatagtatta attaatccct
    63601 caagagttaa agggactgga ataggataag atactctacc agctatatct attaaatcac
    63661 agttacaagc agaaaatctt tcaaaagtac catcaagtcc agataaatta tcttttggag
    63721 gagctgaaag atctatacct accaaattag cacctactat aaagaaatct gagataaaag
    63781 caaattgatt aaagtttaca aaaggtctta gagcatcata tcttagaagt tctaatgctt
    63841 ctctcatact ttttttacaa caacattgtt ttattttagg ttctttatat ttatttggat
    63901 aattatagta tctatcagct acttgataat tttcatagta tctttcattt gtatttggat
    63961 aatcttcctc atattcttgt gtaaatctaa agtcctctct acatttatta ttttccacta
    64021 aatacactcc ttttatattt taatttaaat gtatagataa ttaagcttat ctatatagta
    64081 atattatatt tataatgtaa aaaaatgtta caaaagatat tataaacgaa taaaaaataa
    64141 taatttgcca gataaacttg taaattttta tgaataatcc attctaaaac aaaaaactgt
    64201 gtataaaaaa ggtttatatg ttatatttat ataaatataa catatgaacg agaaaggagt
    64261 ggtttgataa atgattgagg tagataaatt gtgtaagtct tttacaaggg ttgtaaaaga
    64321 tgataagaat aaaagttcaa taagaaagct aaagaaagta aaaactaaaa aagaagaatt
    64381 ttttgctgta aataatgttt catttaaagt tatggaaggt gaaattgttg gaatattagg
    64441 tccaaatggt gcaggaaaga ctacattact tagaatgtta ggtggcatat taacaccaac
    64501 atcaggaagt ataaatattt ctggatatga ttattcaata gatagaaatt cagcaaaaaa
    64561 agaaataggt tatctctctg gaaatacaaa actatatgga aggctttctc cgagagaact
    64621 tctaacaact tttgcaagtc tatatgagat gtcaaaagaa gatatagaag aatcaattga
    64681 aaatattgta aaaataatgg atatgagtga atttatagat aatagaattg aaaatctatc
    64741 aactggtcag actcaaagaa catctatagc tcgttgttta atacattctc caaaagtata
    64801 tatttttgat gagccaacac taggtctgga tgttttaagt agtgcatcta ttatagattt
    64861 tatgaagaat gaaaaactaa ggggaaaaac tgttctttac tcaactcatt atatggaaga
    64921 agcagaaact ttatgtgaca agatttttat gattcacaat gggaaaataa ttgcatcagg
    64981 aacaccacag agtttaaaag aggaatctgg agtaaataat ttgagagatg tattcataaa
    65041 acttgccaga aaggaggaca tttaaatgag aagtaagatt gtaaaataca tatttaaaaa
    65101 agaaatgtta gacatattga gagataaaaa gactttattt atgatgattg ttgtgccact
    65161 tcttttatat cctttactta tgttattaat gattcaagta atgaatatgt ctgcaagtag
    65221 tatgaatagt aaggacatta atatagcttt taataataaa cctaataagg ttttagtatc
    65281 catgattgaa gatgataatt tagaaaaaga tactaaaaat acttcaaatg ataaaggcaa
    65341 aataagagtg ttagatgtag ataactataa aaagtcatta gaagaaaata aaattgatgc
    65401 ttatataaag atggaagaaa aaaaatcatc tataaattat caaatatata taaattcttc
    65461 tcaagaaaat tcttctaatg cactaaaaag aattgaaact gttttggata aatataaaag
    65521 atttaccata gaaaaaactt tatctgaaaa aggattagat gtacaagcta ctttagaacc
    65581 aataacatat agcactgtag atgttgcaaa gacggaagaa gtggcaggat actttttagg
    65641 tcagatactt ccatttatat taataatagg agttttacta ggttcaatat atccagcaat
    65701 agatgttatg gctggagaaa aggaaagagg tacattagaa acattattta cactgccaat
    65761 atcaaactta gaactggtta tgggaaaata tatggcagtt tctcttagtg caatagtaac
    65821 agcaatttta aacattttat ctatgggact gactatggca tttattttag ttagtggagg
    65881 tattagtagc caatttggct ttggaaactt taattatgga gacttagtct taccaattat
    65941 aactacttta atttgcatat gtcttttttc aatggtagtt tcagcaataa gtatgtgtgt
    66001 atgttcatta gcaaaaagtt ttaaagatgc tcaaaactac ataacacctc ttatgttaat
    66061 tattatgata ccatcatatg tttctatgat accaaatata gtattagata gagtgacagc
    66121 tgtaatacct gtagtaaata tatctttact tataaaaagt gtattatctt ttaaaagcga
    66181 tttaaattta atagccttag ttttagcatc aaatgtagcc tttgttatat tggcaatcat
    66241 actactgtct aagatgttca attctgagga aatacttttt ggtaatagta agagtttctc
    66301 tttcttagag aaaagaagta atataaaaaa agggtctata ccaactgtaa gtgatggtgt
    66361 tattttatat gcagtaggat tagttctatt gatttatgtt ggttctttag ttcaaattaa
    66421 atttggtatg gcaggtatta taatgacaca attcatgata atttctttac cgttattatt
    66481 tgcatactat attaaagctg attttaaaga ggtatttagc ttgaaagttc ccaaattaaa
    66541 gcatgtgttt gggagcattg ttctttggat tggtggatac atacttatta tgattataac
    66601 acagctaatt ttattcttat ttcctcaaaa tatggaagtt gctgaaagtt taaataaggc
    66661 tctttttatc aaagatagtg ttttactgaa tttactagca atagctttat taccagcttt
    66721 atgtgaagaa atgtttttta ggggatttat attttcttca tttagtaaat caaaagataa
    66781 aaataagtct atcaagctag ctataatatg cagtggggta ctatttggta ttatgcatat
    66841 ggattttatt agaataattc caacatcaat attaggtatt atatttgcat atagtgtgta
    66901 taaatctggt tcaatatttg tatcaatgtt attgcatttt ttaaataata gtgtagcagt
    66961 tgtgttaaat cattatacaa ctggaaatat aaccaactta tataaatttg ttgaagttga
    67021 tttttcgaac ttaaatgtac ttaaatttgc cttaattctt ctaataagtc ttatattaat
    67081 tatgttagga ttaagagttt tagatagaaa gtctttaaga aattaagtat aaagttatta
    67141 tatagattaa aatatta
//
LOCUS       DAMJVG010000012        65386 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.012, whole genome shotgun sequence.
ACCESSION   DAMJVG010000012 DAMJVG010000000
VERSION     DAMJVG010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 65386)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65386)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65386
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.012"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            79..1275
                     /locus_tag="PC512_000876"
     CDS             79..1275
                     /locus_tag="PC512_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HDF2440646.1"
                     /translation="MKILVLNCGSSSLKYQLIDMNNEEVLCIGLVERIGIEGSILKHE
                     KAGRDDKYVVEQPMKDHKDAIALVLEAVAHPEFGAVKEMKEIDAVGHRVVHAGEKFAT
                     SVVITPEVEEALKECIDLAPLHNPANIMGIDACKAILPDVPMVGVFDTAFHQTMPKSS
                     YLYGLPHELYTKYGVRRYGFHGTSHNYVSQRAAEILGKDIKDLKIVTCHLGNGASIAA
                     VDGGKCVDTSMGFTPLEGLIMGTRCGDIDPAILPFLMRKEGLDADGLDKLMNKESGVY
                     GMTGISSDFRDIEDAAKNGDERAQATLEAYVKKVQKYIGAYAAEMNGLDVVVFTAGVG
                     ENGKAIRADIASNMEFLGMKLDKEANDVRGKETVISTADSKVKMLLIPTNEELMIARD
                     TLRLVK"
     gene            1368..1892
                     /locus_tag="PC512_000877"
     CDS             1368..1892
                     /locus_tag="PC512_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HDF2440647.1"
                     /translation="MKVSIEKINRKETDKIDLNFCEKIDTISYCDEIYKLVSPVNLKG
                     KVSKTNKGLYLDIDVNFTIVDNCSRCLKEVEIPLEYSIQGFLVKEEDYDEDEFEEFDP
                     FIFDGEEIDLIDIIEQTLDFNVPHKVLCSENCKGLCQVCGANLNEEECSCSEITNDEE
                     YIDPRFAKLKDLFN"
     gene            1917..2093
                     /gene="rpmF"
                     /locus_tag="PC512_000878"
     CDS             1917..2093
                     /gene="rpmF"
                     /locus_tag="PC512_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HDF2440648.1"
                     /translation="MAVPKRKTSKSNTKMRRAANSKMEATGFVSCPQCHEPKLPHRVC
                     PDCGYYKGKEVVSK"
     gene            2300..2857
                     /gene="fapR"
                     /locus_tag="PC512_000879"
     CDS             2300..2857
                     /gene="fapR"
                     /locus_tag="PC512_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription factor FapR"
                     /protein_id="HDF2440649.1"
                     /translation="MKKKSKAQRQKELIDMLKTDPFYTDEELSSLFDVSIQTIRLDRM
                     SLNIPELRERVKSIAETQSSKVKTLGVKEITGEIIDLSVGRLGISMLEVTQDMIYSKT
                     NTLKDTYIFSLADSLAMAIIDAPKVIMRVANVKSFKLIEQQDRLIAKAEVYRNIDKKH
                     YVKVVINNKAQEQIFRGKFIFEELD"
     gene            2868..3890
                     /gene="plsX"
                     /locus_tag="PC512_000880"
     CDS             2868..3890
                     /gene="plsX"
                     /locus_tag="PC512_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HDF2440650.1"
                     /translation="MKIVIDGMGGDNAPKSNVEGAVNAIKEYQVDLIITGDKDLLEKE
                     FSNYEFDRNKLEIVHTTEIIENEDKPVKAIRSKKDSSMVVALNLVKEGKADAIISAGN
                     TGALLAGGLFVVGRIKGIDRPCLCSAIPNVKRGMTLIADCGANADCKPKNLVEFAAMS
                     NIYSRKVLGLENPKVALANVGLEEGKGNDLVKRSYEEIKKLDLNFIGNVEAREVINAY
                     TDIIICDGFTGNILLKSAEGVALSVMSLIKETFMASTKSKIGALLIKDDLRKLKSFID
                     YSEYGGAPLLGLNGGVIKAHGSSDAKAIKNAINQGIKFSKGKVVEDINQFISKYNEEN
                     KNNEDE"
     gene            3916..4902
                     /locus_tag="PC512_000881"
     CDS             3916..4902
                     /locus_tag="PC512_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HDF2440651.1"
                     /translation="MNTKAGILGVGSYLPEQSYDNFHFEKIMDTSDEWISTRTGIKER
                     RFAKESEATSDLASKAALKAIECAKLNVEDIELIILATITPDMSLPSTACIVQDAIGA
                     VNATAFDISAACSGFVYGVTIAKQFVETGCYKNVLVIGAETCSKFLNYDDRTTAVLFG
                     DGAGAAVIGPVNEGGILSTHMGSDGKGKDCLKVPAGGSRLKASKETVEANLHTIEMAG
                     SDVFKFAVRKMAETSLRALEKANLNTTDIDYLVPHQANIRIIQASSKRLELDMKKVYV
                     NIDKYGNMSAASIPVALDEAYREGKIKKGDNVVLVGFGGGLTWGASVVKWTL"
     gene            5011..5940
                     /gene="fabK"
                     /locus_tag="PC512_000882"
     CDS             5011..5940
                     /gene="fabK"
                     /locus_tag="PC512_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HDF2440652.1"
                     /translation="MNKICKILNIKYPVIQGGMAWVATASLASAVSNAGGLGIIAAGN
                     APKEAIKKEIVECKKLTDKPFGVNVMLMSPFVDDIIDLIIEEKVQVITTGAGNPAKYM
                     DRLKEAGTKVIPVVPTIALAQRMEKLGATAVIAEGTEGGGHIGELTTMVLVPQVADAV
                     NIPVIAAGGIVDGRGIAASFALGASAVQVGTRFICSEECSVHSNYKNLVLKAKDRDAI
                     VTGRSTGHPVRTLKNKLSKEFLKMEQNGATPEELDKKGTGALRFATVDGDIEKGSFMA
                     GQSAAMVKEITPCKEIIEAMVNQAREIMPAIEL"
     gene            5956..6906
                     /gene="fabD"
                     /locus_tag="PC512_000883"
     CDS             5956..6906
                     /gene="fabD"
                     /locus_tag="PC512_000883"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HDF2440653.1"
                     /translation="MGKVALVFPGQGAQYVGMAKDLYENNTVAKSVIDEASDALNMDL
                     KNLMFNGNEEELSKTENTQPAMVTHSVAVLKAVQAQVDLKYSACLGLSLGEYSALVAA
                     DAIDFKDAVCLVKKRGKFMQDTVPTGVGAMAAILGLDRSILENVVKDIQGGIVEVANY
                     NSPGQIVISGENEKIEEAMVKCKEAGAKRAVKLNVSGPFHSSMLREAGVKLASELEKV
                     NITKPKVDVVANVNADYYKNEGKDLLIKQVSSSVLWEDSIERLLNDGYDTFIEMGPGK
                     TLKAFIKKIASNKKANVNIYNIDGIDSLNEFVQNYRNGEI"
     gene            6906..7655
                     /gene="fabG"
                     /locus_tag="PC512_000884"
     CDS             6906..7655
                     /gene="fabG"
                     /locus_tag="PC512_000884"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HDF2440654.1"
                     /translation="MINLTGQVAVVTGGSRGIGKEIAKKLASFGADVVINYTSKEDEA
                     LKTKNEIESMGVKCTSIKCDVSKFDEVNQMIDSVVSEFGKIDILVNNAGITKDGLLMR
                     MKEEDFDRVIDINLKGVFNCTKAVTKPMMKKKYGRIINMTSVVGIMGNAGQTNYCASK
                     AGVIGFTKASARELASRNININAVAPGFIETDMTKVLSDDVKESTLANIPKKSYGKPE
                     DVANAVAFLVSDMSSYITGQVINVDGGMVMQ"
     gene            7709..7933
                     /gene="acpP"
                     /locus_tag="PC512_000885"
     CDS             7709..7933
                     /gene="acpP"
                     /locus_tag="PC512_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HDF2440655.1"
                     /translation="MFNKVVEIIIEQLGVEDKEITMETSLMKDLEADSLDAVEIIMAL
                     EDEFGIEIPDTEAENFKSIGDIVKYIEANK"
     gene            7962..9200
                     /gene="fabF"
                     /locus_tag="PC512_000886"
     CDS             7962..9200
                     /gene="fabF"
                     /locus_tag="PC512_000886"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HDF2440656.1"
                     /translation="MNKRVVITGLGCVTPLGTGKEEFWSNIKSGVSGIDKITNFDAST
                     YQTQIAGEVKNFHPEEYISKKELKRLDKFAQFAIVSAKLAVEDANLDLDKVDRERFGV
                     IIGSGIGGVEAIETQHKILLEKGNKRVSSLFVPMMIGNMAAGQVSIFLGAKGPNTNVC
                     TACASGTHSIGDAFKVIQRGDADIMVAGGSEAAVTGLAFAGFCNMKAMSTRNDDPKTA
                     SRPFDKDRDGFVMGEGAGIVILEDLEHALARGAKIYAEVVGYGLTADAYHMTTPAENG
                     EGAARSMNMALKDGNVPLEEVDYINAHGTSTYYNDLYETMAIKTVFGEKAYDLCVSST
                     KSMTGHLLGASGAIEAVVCAMSIEDSFVPPTINIQEVGEDLDLDYVPNQGKEKNIRYA
                     LSNSLGFGGHNATIVLKKYV"
     gene            9426..11144
                     /locus_tag="PC512_000887"
     CDS             9426..11144
                     /locus_tag="PC512_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF2440657.1"
                     /translation="MNFRLPKKRLPKKIIFICIILISIILFIKHDQNGLKEREIINKG
                     KYMSESLVADKEYDEAKKVVKTSFESIPEKKYNKVYNEVWDMLKTISYVPDGTKIVID
                     SLEKMRESDVKLSDECRFNIEKRLASVYIMDNNYSKAVDLTVKSIKLAEKLGNNYEKA
                     RLDVDLASIFLKIGGYETGEKLIKDSFKIDIDEGEKNGMVRLYAIINLAEIYVEEGEY
                     DKAIEISSRIKDYKKFVNTDNYNDFDIMASIMQSNAYVGKNNIQKAKTFLEKADYLIK
                     SDRTVYILDKDMYYYMAMGNLEYKSENYNSAIDNYKKSLEISTKRKLTQEKIKNLNKI
                     LNIYEKQGNIESLNEYQKMLINEYKENKSIRDSETSFYIIDKVSNESKLFEKTKKEIK
                     YYKILFTVILIAILGSTFLYNRLKYFKAQNLHDGLTNVYNRKSFDIMYEKYREKDDNF
                     ALVMIDIDNFKLINDNYGHKFGDTVIKGITNTICVMLEQDDKVFRYGGEEFSVLIRNK
                     SGDEVADIIDSIRVAIANKKWNDDVTVTISAGVAHVSDSKDVLEEADKNLYKAKQLGR
                     NKVVYK"
     gene            11175..13175
                     /locus_tag="PC512_000888"
     CDS             11175..13175
                     /locus_tag="PC512_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2440658.1"
                     /translation="MKQSIAIVTDKITKLSSFLEENIRLVLGNYIDINHYYLEVLKEN
                     DKIQGDFVLVMNDDRLNSMRKHLVQDSKIIVIRRTLKENEIYGLFSIPNGTEVLVVND
                     TKETTLETISLFYKIGVKNLKFTPYIEGKIYKNIDIAITPGVKGKVPSYINKVIDLGN
                     RYIDISTFIEIINGLRIDVKEIRKNLMAYSESLISLDNGVKDNYRQLFLKIEEQDVIL
                     NLSKDGIIFTSADGIINTFNKEALKILGINENPQGKNIEDIISEDLNILLEDKEIIDE
                     VVFTNKKYINVNKKSIFSMGNKAGIYYNLQEITYIKKLEQNLTNKLREQGQIARYTFK
                     DIKTKNKNMVKCVELAKKISKSELSVLIIGESGTGKELLSQSIHNASNRSNQPFIAVN
                     CAAVPDSLLESQLFGYEKGSFTGALREGKKGLFELANNGTIFLDEIGDMPPLLQTKLL
                     RVLQEKQVMPIGSHNVINIDVRVIAATNKNLLKMIREGKFREDLYYRLNVLPIDVPSL
                     RNRKEDIITLMNFFLKNNIRLSPEVITILEKYNWPGNIRELQNVASYVSLMCDSMVFR
                     DDLPPYIRVECANNYEDGFGYTRKEFEEILRILYERRESSSGIGRGFIIEKLIQEGIE
                     ISESKVRKVLSYLSECGYISSKSGRGGSQITSEGIKLYNNIN"
     gene            13526..13771
                     /locus_tag="PC512_000889"
     CDS             13526..13771
                     /locus_tag="PC512_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03905 family TSCPD domain-containing
                     protein"
                     /protein_id="HDF2440659.1"
                     /translation="MKYKTTGTCATEIEFEVKENKVTNVNFIGGCDGNLKGLKVLVEG
                     MNIEDVIQKLKGIECKTKPTSCPDQLSLALENYMNIK"
     gene            13806..14531
                     /locus_tag="PC512_000890"
     CDS             13806..14531
                     /locus_tag="PC512_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HDF2440660.1"
                     /translation="MKPIIGILGNLIIMENGMFPGLERSYVNNDYINAVLKGGGSPVI
                     IPVNTDKEVIKKQIEMVDGVLISGGWDINPQLYGEETREETTFIYPEVDEFDLIAISI
                     ALELKKPILGVCRGLQILNVSLGGTLYQDNNLIEGSYIKHTQSSKRHVATHKVDVKEG
                     SILEGILGKQLLTNSYHHQSVNQLGKGLKAIAYSKDGIIEAIEKEDENFVVGVQWHPE
                     MMVDYCDKMEKLFKYFINICSNL"
     gene            14553..15866
                     /locus_tag="PC512_000891"
     CDS             14553..15866
                     /locus_tag="PC512_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDF2440661.1"
                     /translation="MNEKNKMGLISIILLGINAVVGAGVFLLPGDAMKSFGVASIFVY
                     IFDMLLVLSMAFCFAEVAGKFNKNGAAYVYTKEAFGDFCGFEVGLMKWVIGCISWGAL
                     IVGFPTSLSAVWAPAGEPHIQKIIIVVMIVGLTIINLLGVSLSKIVQNVITVGKLIPL
                     ILFIGIGIFFIKGVNFTSSTMVPPGAGATEFGAAALLMFYSFTGFESIAVAAEDMENP
                     QKNIPIAIISVIVIASIIYILNQVVCVGILGDSLSSTSTPVADAARICFGNMGAGLVT
                     FGTLVSVGGICMCGAFVNPRSCVALADDKMLPRIFARKDKKGTPYVAIIATMLITIPI
                     ALSGSFAELAAISAVARFIQYIPTSLSVLVFRKKRPELVGTFKTPFGAVIPLIAVCVG
                     TWLLFQASMHQLIMGLGALAIGVPLYFIMKSYNRKVYDENLKKIV"
     gene            16072..16611
                     /locus_tag="PC512_000892"
     CDS             16072..16611
                     /locus_tag="PC512_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2440662.1"
                     /translation="MPTITLKNGVDVLIREGVREDAQSIIDFYNEVGGETHFLSFGKD
                     EYKISLEEQENAIESAKASDNSVKLIAFIDGEIVGIATIDSNQKAKGKHVGVLGIVVK
                     EKYWGIGLGKRLMLDLIEWCKSNGITKKITLVTNEENYNAIGLYKKVGFEVESILKKE
                     CYYNGVYTDLIGMSLLLGI"
     gene            16700..18685
                     /locus_tag="PC512_000893"
     CDS             16700..18685
                     /locus_tag="PC512_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-1,6-bisphosphatase"
                     /protein_id="HDF2440663.1"
                     /translation="MKNLCKISDDYLNSKLKYLKLLSKQYPSISKASTEIINLEAILN
                     LPKGTEHFITDVHGEYEPFVHVLKNGSGVIKRKIEELFSNTIRDSEKKMLATLVYYPE
                     QKLDLIIKQEENIDDFYRINIYRLIELCKYASSKYTRSKVRKLLPENFKYIIEELLHE
                     HVKSEHKEEYYKSIVETIVDIGIAKEFIIAISTVIQKLVVDRLHVIGDIYDRGPRPDI
                     IVDKLIEHHCVDIQWGNHDILWMGAASGEKTCIANALRISARYANLDIVEDIYGINLL
                     PLATFAIEMYKDDPCKEFIPKVNDQSVTTTEKSLMAKMHKAISIIQFKLEGEVIRRRP
                     EFEMEHRLLLNMINYDEGTINLKGKTYKLKDTYLPTIDKKDPYKLTMEERNVIDKLVS
                     SFRGSEKLQKHVSFLFSKGSIYLKANSNLLIHGCVPLNEDGSFMSMNIMGKEYKGKAL
                     MDKMESLAREGFFFKDKAEEKLYGMDIMWYLWTGKCSSLFGKDDMTTFERYFIAEKET
                     HKENKNPYFKLRENEMACKRLFEEFDLELDESHIINGHVPVESKNGESPIKANGKILV
                     IDGGFSRAYQKTTGIAGYTLIYNSRTLQLVSHEPFNSAEEAIANESDILSTTVVVEHK
                     AKRKMVRDTDEGVKIQEEIEDLKLLLMAYKKGLIKEM"
     gene            18909..19877
                     /gene="spoIIIAA"
                     /locus_tag="PC512_000894"
     CDS             18909..19877
                     /gene="spoIIIAA"
                     /locus_tag="PC512_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AA"
                     /protein_id="HDF2440664.1"
                     /translation="MNKLSDEIINSLSTTIREKVEKVSNNNLNIEEIRLRSQKPLILN
                     ANSKDYFYNQKTMTLDLNQQNSYVVTREDVEQTFQIICKYSIHSFMDDIKKGFITLRG
                     GHRVGLVGKAIVEDGQVKNIKHISSLNIRVSREIIGCSDKILSHIIKGKNQINNTLII
                     SPPQCGKTTLIRDIVRNLSNGNEDYGFKGLKVALVDERNEIAGAYLGVPQMDVGIRTD
                     IIETCPKDLGITMLLRSMSPNVIVTDEIGSEKEIKALYTALNGGIGLITTVHGDSIED
                     IQNRKELNRLLDKELFKKVIILSAKRGAGTIEKIYDLEEKRWYFAN"
     gene            19867..20388
                     /locus_tag="PC512_000895"
     CDS             19867..20388
                     /locus_tag="PC512_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AB"
                     /protein_id="HDF2440665.1"
                     /translation="MQIKIIIIAFLIGSSYLIGEQIYKTYTRRHKQLNDLIRVLEILR
                     MDLSFGLYTLEEIFNRIGGNKEFCFWKFFYQISEGLHNEQSKTLEIIISENIDVLSKE
                     TYLGNKEIEELKNLILTLGKSDIESQQRMIDLSIENLKKQTYETKEDINKKGVLYKKL
                     VTFIGIGICIILI"
     gene            20405..20602
                     /gene="spoIIIAC"
                     /locus_tag="PC512_000896"
     CDS             20405..20602
                     /gene="spoIIIAC"
                     /locus_tag="PC512_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018589775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AC"
                     /protein_id="HDF2440666.1"
                     /translation="MEISLILKVAGVGILISVLNMILEKTDRKDWAGLTTLAGVIIVL
                     GMVITEISDLFNTVRTMFQLY"
     gene            20618..21004
                     /gene="spoIIIAD"
                     /locus_tag="PC512_000897"
     CDS             20618..21004
                     /gene="spoIIIAD"
                     /locus_tag="PC512_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AD"
                     /protein_id="HDF2440667.1"
                     /translation="MEIMQLIGIAIISTTLCLVIKKDRPEIANFIAIITGVIILLSVM
                     FKLNFIVDSIQDLANKANIPTMYISLIIKLIGIAYLMEFAIQLCKDCGEGNIASKLEF
                     GGKIIVMSMSFPILLSIVEMVVNIIP"
     gene            21089..22294
                     /gene="spoIIIAE"
                     /locus_tag="PC512_000898"
     CDS             21089..22294
                     /gene="spoIIIAE"
                     /locus_tag="PC512_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AE"
                     /protein_id="HDF2440668.1"
                     /translation="MKKRFLPMIIGFLFTFFFVNIFAIMIFANEVPSSEDKEYGETKN
                     SIDKYIDGQLDKLDINEIQDYINKEIVINDVNLKSFVKDLISGEKNILDLFNKDGLKI
                     LMFDEFKASLKVVAVILVLALLSSILKSLENSFSSGAVSQIATYIIFITMVSLTLIGF
                     KDVLQICYDAIDHTVGLMQVIMPILITFLLLIGFPITSTTLNPIFIGGVTFINVFFKN
                     FLFVSITVAFGILIINNLSKNIRLKRFFSFVKQINYVSIGAMFTVYLGLVSIQGLYVT
                     SFDKFSVKTAKFAIGNFIPVVGGFVSDSVDILLSSSQLIKNIFGGIGLILLVGICLLP
                     VIKILSVIVVYKLAAIIVEPVGEDGISNFLNEVANLMIIMLASVIAITVMFFVTVAIL
                     TSISVVSQG"
     gene            22354..22971
                     /locus_tag="PC512_000899"
     CDS             22354..22971
                     /locus_tag="PC512_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AF"
                     /protein_id="HDF2440669.1"
                     /translation="MLEGIKAWIVSVLIGAFIVNIVDMILPSSKIKPYVNLVLNFMFV
                     FIVITPVVGFFSKDMSLEDRILKSMGNYNKQYVDSTNALAKETGNNSLSKGYEDGLKE
                     VLKLKLDEYGYDLEDIELNGANINNIKIKEKNNSAKSNNSSNEENKNNSTKREEENIN
                     SNDKENSKQVFKKGTEYGLNLNEEKLKNDLIKVLDVSIEDIQIDK"
     gene            22983..23537
                     /locus_tag="PC512_000900"
     CDS             22983..23537
                     /locus_tag="PC512_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AG"
                     /protein_id="HDF2440670.1"
                     /translation="MLKNLNDKDKRKVYSLITIAGICVVSLVLLSCFPSSKSDKQVGK
                     TETNKNAEKQVTKEQEKDDLESKLTAILSKIDGAGDVDVMVTFESSEEIQPAFNSNNT
                     TETTEEKDAQGGERTVTTSSENKTMITSNSSDPVVIKTTEPKIKGVIVVASGASDPSV
                     KETLYSAVQTSLQVAGHQVEIYSK"
     gene            23564..24253
                     /locus_tag="PC512_000901"
     CDS             23564..24253
                     /locus_tag="PC512_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIIIAH-like family protein"
                     /protein_id="HDF2440671.1"
                     /translation="MKFNYKGRGFVIITLTAMLVVVGTVNYQLSKKSLLETSKEFKAY
                     EEAQLQKNTDDSYSSKTEDSSNVDKQGGKESADIDIVDSKASKVKEKATETSKEIKAQ
                     LSSEKNMKKASYILDMKMNREKQRNELVQDLNEMINNPSTTEESRKEASNMKLNIVKI
                     QEKELQIENLLSTKGYEEALVYISDNKVNVVVNEAKLEKKDAAKIFDLVAEQANVKYE
                     NIKLTNNNSNK"
     gene            24363..24725
                     /locus_tag="PC512_000902"
     CDS             24363..24725
                     /locus_tag="PC512_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HDF2440672.1"
                     /translation="MEDNKFGQVKISNDVIATIAGLAALEVEGIETTATLTDKLLKNN
                     GVKIQIEEEDVNLDVMVTIKYGMSIPDTAFKVQENVKNTVETMTGLKVSQVNIHIQGI
                     SFKKDKVDKEEAKATKKN"
     gene            24810..25316
                     /gene="nusB"
                     /locus_tag="PC512_000903"
     CDS             24810..25316
                     /gene="nusB"
                     /locus_tag="PC512_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HDF2440673.1"
                     /translation="MKKDRAQKSTTREYIMKLIYQININKEDFETLEDKVDNFLKDNS
                     EHIINRYKELALQYSKNTNLKLEDTEIEDVIDKKYINTVCKALKENHDKIDELINKHA
                     KNWTVDRMPKVDVSILRLSVCEILYLDTPNKVSINEAVELAKIYCDDKSPKFINGILG
                     SVVDEIGK"
     gene            25300..26370
                     /locus_tag="PC512_000904"
     CDS             25300..26370
                     /locus_tag="PC512_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-sialoglycoprotein endopeptidase"
                     /protein_id="HDF2440674.1"
                     /translation="MKLGNNIIIGIDTSCYTTSIAAISLDKKVIFNEKIMLEVRDNSK
                     GLRQSEAVFQHINNLGILSDRIKSFKDKFNVEGVCSSKKPRPVENSYMPVFNVGHNFG
                     KLLSSIYGCRFYETTHQENHIEASLLNSKLKNNNKFISVHMSGGTTEILLTSKQDSHH
                     NVCDTNLGKIAKISIKKDDKSKLYNNFGYNIDIIGGSKDISFGQLIDRVGIKLGYKFP
                     SGKYLDENALNCNLKIESGLKTSVRDGYMNLSGLENQVNKIINDNGDNTNQKEYISKL
                     VLDSVVRNMFKSLVYLCETYNVNEVVFAGGVSASKYILRELSMKLRKKHIEAYFTEPQ
                     YSTDNAVGCAIIGLNNFLGERV"
     gene            26367..27572
                     /locus_tag="PC512_000905"
     CDS             26367..27572
                     /locus_tag="PC512_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HDF2440675.1"
                     /translation="MKLRALDISEANSYIKRILINDPILSNLKVKGEISNFKVHSSGN
                     VYLSLKDETSKLNCVIFKSNFNRNLKLDNGVKIIANGYISVYERDGAYQLYINEIEIE
                     GIGNLHIEFNRLKEKLNKEGLFDPKYKIPIPKMPNSIGVITSPTGAVIRDIINVIKRR
                     YPKVNIKLYPVTVQGDKSAEEICEAIRFFNHMKNVDTLIVGRGGGSIEELWSFNDEMV
                     AREVFNSQIPIISAVGHETDFTICDFVSDMRAPTPSAAAEIATPSLDDINYKLGNIKS
                     RMSKSLTNQIELDQYRLETVFNKINNYLDSYTIKDKVIQLDKIYDKIIFGIENNLKLE
                     DEKLVKIGALLHNLSPLATMDRGYSITQKNGKVINSIKGLKIKDSIDIVLKDGNLECM
                     IDKIENKEG"
     gene            27574..27789
                     /gene="xseB"
                     /locus_tag="PC512_000906"
     CDS             27574..27789
                     /gene="xseB"
                     /locus_tag="PC512_000906"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HDF2440676.1"
                     /translation="MNLTYEEAYKRLESILSELESKNASLDESLSLYEEGISLYKHCN
                     KLLDDAKLKISKFNQLGIEEDFKIEEE"
     gene            27792..28679
                     /locus_tag="PC512_000907"
     CDS             27792..28679
                     /locus_tag="PC512_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HDF2440677.1"
                     /translation="MEFKQCLKEKASFVEKVLKEYMPKEEGYQKTVIEAMNYSLSAGG
                     KRLRPILTLEACKIVGGNEDEAIPFAIAIEMIHTYSLIHDDLPALDNDDLRRGRPTNH
                     KVYGEAMGILAGDALLNYAFEVMLAGSINKENPEKYLKAINEIAKGAGIYGMIGGQVV
                     DVESENKQIEKEKLDYIHMNKTAAMMVGCMRAGATIGGANSEQMEEITKYAKNIGLSF
                     QIVDDILDIVGDEAKLGKKVGSDIENHKSTYPSLLGLDKSKEIAHNLIDEAKKSIEKL
                     SDDVDFLKGLAEYIIDREY"
     gene            28709..29146
                     /locus_tag="PC512_000908"
     CDS             28709..29146
                     /locus_tag="PC512_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divergent PAP2 family protein"
                     /protein_id="HDF2440678.1"
                     /translation="MDFFSEIFNNGALGISLIACFLAQFIKIFTGKEKRIELSRILIS
                     GGMPSSHSSFVTSLATVVGIEKGFNSTDFAIITVLALIIMYDAAGVRRAVGKQATILN
                     QMVADIQHGKHIEQKKLKELIGHTPLEVWFGALLGIVTALILM"
     gene            29180..31045
                     /locus_tag="PC512_000909"
     CDS             29180..31045
                     /locus_tag="PC512_000909"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HDF2440679.1"
                     /translation="MYKYLDKVNSPKDIKNMSIEEMDLLAKDIRKFLVKSVSKTGGHL
                     ASNLGVVELTLALHKVFDSPKDKIVWDVGHQSYVHKIVTGRKDCFVSLRQFNGLSGFP
                     KENESPHDIFDTGHSSTSISIATGIACARDIKKENYSVISVIGDGSITGGMALEALNQ
                     LGYIDTNMIVILNDNEMSIDKNVGGMSKYLSSIIRNSTVEKMTDEVDKILNVTQTGEI
                     LSKTAHRFKDKLMYSFSPQDCSFFDSLGIRYYGPIDGHNTKELIDILRKAKHKKGPVL
                     LHVITKKGKGYRFAEEQPDKYHGVSKFDIKTGVTSAKVKSMSISVGEKLVDMANSNEN
                     IVAITAAMPSGTGLNLFESAYPKRYYDVGIAEQHATGFAAGLAKNGMKPYFAVYSSFL
                     QRAYDQVIHDVCITKKPVTFLIDRAGLVGNDGETHHGMFDLSYLNSIPNIVVMAPKDT
                     REMELMMDLSLKLDCPLAIRYPRGSSYYLDKGEYGEIVLGKYEVLDDGQDTVILCIGS
                     MVKHALEAKEILSREGINPTIVNARFLKPIDEGMLKALLKNHKNVVTIEDNIVTGGFG
                     SRINKFIIDNEYNVNILNIAIPEEFVKHGNIDELYDFVGLSPKSIADKIRKLVIE"
     gene            31178..31990
                     /locus_tag="PC512_000910"
     CDS             31178..31990
                     /locus_tag="PC512_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family rRNA
                     (cytidine-2'-O)-methyltransferase"
                     /protein_id="HDF2440680.1"
                     /translation="MKKRIDLLLVEQGYFESRERAKKAIMAGLVFVDNQRCDKAGTEV
                     KEDCSIEVKGNPIPYVSRGGLKLEKAMKNFDLTIDGKVCMDIGASTGGFTDCMLKNGA
                     IKVFSIDVGYGQLAWKLRQDDRVVCMERTNIRNVTIEDTKQFADFASIDVSFISLKLV
                     LPKAKELVRHDGEVVALIKPQFEAGREKVGKKGVVREKSTHIEVIKMISDFSVENGFE
                     ILGLDFSPIKGPEGNIEYLIHLRNGNEGYEFDGETYNNKIVEVVEASHNLDK"
     gene            32010..33689
                     /gene="recN"
                     /locus_tag="PC512_000911"
     CDS             32010..33689
                     /gene="recN"
                     /locus_tag="PC512_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HDF2440681.1"
                     /translation="MILELYMKNCALVEELRLNIDKNLNILTGETGSGKSIIIDALGL
                     CLGDKYDRSFLRKGTDKGLVEAVFFSDNRYLKKILEENDISMEDDNLLVITRLIYSDG
                     KSTARVNGRTVKVSLLKEIASTLIDIHGQHQNQALFNKDTHLKFLDLFGENELEEFKI
                     AYKNVYHKYSEVKKALNCLTENKDEMQIQREIDLLRFQINEIEAANLNKNEYEDLLKQ
                     REVYRNSEKIYNNLNSSYSKLHNGEYNVIDLIGLASKELNDISKYDSVLSEYSDTVER
                     IMYELQDISGEIRNYKDNIDFEPYELEQIELRIDEINNLRRKYGDSIDDIFEYYGKIK
                     DRLDEILNRDERVEQLRSKLMNIEEDLKIKASKLTKARIEVATTLEKILLDELKSLNM
                     KNVMFKVNFEKGPFTLDGVDDIEFMISFNLGEDIKPIYKVASGGEMSRFMLAFKTILA
                     DIDDIDTLVFDEIDTGISGIAAQIVGEKLSDIAKKKQIICITHLPQIAANADTHYCIE
                     KDTSNNRTFTNVSKLNESQRKNEIARLIAGNNITEKTIEHASEIIELAKKC"
     gene            33904..34770
                     /locus_tag="PC512_000912"
     CDS             33904..34770
                     /locus_tag="PC512_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440682.1"
                     /translation="MNKKDTMHLIFIIVIFILLWYIVVAVSEINKNIESCSNKLDYLS
                     QELMSTKSDISNTINEEMSKSYITKSIDLKVKKIEKKECIIDIDVQLSKLGKNGKVFF
                     MYKEDSDKWNETEMTKHGELSYACEIKINTGSEYDYKVVTSGAISESSDVQKLTKSDY
                     MPEQPIFNSGIRDNREYFIEIVENSNLFNHESEKSKNKVYDNIRLEKVDIIVNEGKKD
                     TIYKAKLAEGLDDGKTNNSNRNQVNYEVSFPKRDIDDIIYIKAKLTYNNGVEYTKDIT
                     EDITMGLQDLEK"
     gene            complement(34863..35354)
                     /locus_tag="PC512_000913"
     CDS             complement(34863..35354)
                     /locus_tag="PC512_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2440683.1"
                     /translation="MADKMAQNITLQFVEEKDLENLENVKLLFTEYSNSLNIDLCFQD
                     FNNELKTLPGKYKKPSGSLILAFVDENLAGCVALKKLEGKICELKRLYVRNQFRGLKI
                     GKILLEEIIEEAKKFGYTHMRLDTLPSMKSAQGLYEKFGFYDIEPYTYNPIEGARYME
                     LKL"
     gene            complement(35415..35855)
                     /locus_tag="PC512_000914"
     CDS             complement(35415..35855)
                     /locus_tag="PC512_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2440684.1"
                     /translation="MKLNVRIADINNWHDLVSLSVDKSQLDYIESNALSIAESKFITA
                     WVPVGIYDENSLIGFAMYGRLEDDRVWLDRFMIDSKYQGKGYGKASLDFLVNHLKNEY
                     NCDELYLSIFEDNKMAIKLYKDFGFEFNGELDYGGEKVMVLKSN"
     gene            36016..37074
                     /locus_tag="PC512_000915"
     CDS             36016..37074
                     /locus_tag="PC512_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S55"
                     /protein_id="HDF2440685.1"
                     /translation="MNKINKNFKNIWIILGAVSIFTMVIIFNKNCNVNKETQIEAFTI
                     KNHDKKFVYPMGNIIGVKANTDGVLVLGYEEEDVDYIGGIQIGDNIVKIDNKRIKNSQ
                     DVSEILNKIKKSKVEVTFERKNKYKTEVIETKKENGKYKLGLWVRDKISGIGTMTFYD
                     PSMEKFKAIGHAIKDSDTNELLKIKQGYIYKPEQLKIVKASNEKVGKIKGDFNDSNLM
                     GNFSNNSELGISGNITENHNKEFNVANKEKQLIEVGRPQDVKIGGAVILFEDKNKNIT
                     SYDIKIESIVYDKGNYRDMVIKVVDDKLLEYTGGIVQGMSGAPIIQNNKIIGAITHVF
                     RDNPKKGYGIFIDEMIKL"
     gene            37216..38040
                     /gene="spo0A"
                     /locus_tag="PC512_000916"
     CDS             37216..38040
                     /gene="spo0A"
                     /locus_tag="PC512_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation transcription factor Spo0A"
                     /protein_id="HDF2440686.1"
                     /translation="MGGFLVEKIKIVLADDNKDFCQVLKEYLSNEDDIDILGIAKDGI
                     EALDLVKKTQPDLLILDVIMPHLDGLGVIEKLNTMDIPKMPKIIVLSAVGQDKITQSA
                     INLGADYYIVKPFDFVVFINRIRELVSNRVTQVEPKPRPVQETQMTRSDFVKNVGNIE
                     TEITNIIHEIGVPAHIKGYLYLREAIKMVIDNVELLGAVTKELYPSIAKKFNTTPSRV
                     ERAIRHAIEVAWSRGKVDTINQLFGYTVHNTKGKPTNSEFIAMIADKLRLEHSMVK"
     gene            38453..39574
                     /locus_tag="PC512_000917"
     CDS             38453..39574
                     /locus_tag="PC512_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440687.1"
                     /translation="MRVEAPIKVDRKTKKLAKRVESGEIAVINHIDIDEVAANSLVEA
                     KIKLVINAAPSISGRYPNKGPGILTENNILIIDNVGEELFEELKEGETIEVVDGKIYR
                     KGKFLGAGEVLDKYEVSHQIKAAYENLAVELDRFIDNTIDYAKKEKGFILGEVEIPKV
                     KTNYANKHVLIVVRGQDYKEDLSTMLSYIEEVKPVLVGVDGGADALIEFGYTPDVIVG
                     DMDSVSDEALKKASEIVVHAYTDGRAPGLKRVEELGLDAVVFPAPGTSEDIAMLIAYE
                     YKAELIVAVGTHSNMIDFLEKGRKGMASTFLVRLKIGSKLIDAKGVNLLYRSKLKIKY
                     IWALIATALFPVLVVASLSPGVQQFIQLMQLKFRVLLQM"
     gene            39592..40467
                     /locus_tag="PC512_000918"
     CDS             39592..40467
                     /locus_tag="PC512_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper transporter"
                     /protein_id="HDF2440688.1"
                     /translation="MHINMKYYIVTIGAIFIALGIGMLVGFNLNNNQQLSEQQANIIN
                     DLDDKFDILKEKNDKLDSDLASVNRDYEEAVNFINKNVDKILAGSLNGKSIGIISANE
                     NDDYTKNIEDIINKSNGSIAFNIILKENITNPEKLKEMSTKLGTDVKNANDAVNYIID
                     TLKKEDASDILTYLQELDVIKFNFIGDTYLKYDSVVIAGGNDAKDSTKQFEKIEKFVV
                     SKLKSENKYLVEVQNTGVKTSYVELYSKNKVATIDNIDEGIGSISLAILLQQGNIVGN
                     FGRLDTATSLLPSIK"
     gene            40491..41183
                     /locus_tag="PC512_000919"
     CDS             40491..41183
                     /locus_tag="PC512_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDF2440689.1"
                     /translation="MDSYISIIIPAYNEESRIKYTLESILDIKQINEIIVVDDGSIDN
                     TAKVVSELENEKIKFFKLDKNRGKGYALNYGIKLAMKNADIIGFLDGDLGSSAKEVEK
                     LIVPILNGEADVTIAKFPPAKRKGGLGFVKGLAKNSVFEMTGVELDATLSGQRIFKRE
                     VLEKFDEIPFGYGVEVGMTIDILKYGFKIKEVLVNMTHNETGRNLKGFIHRGKQYYHI
                     KKVLGQKKKEWR"
     gene            41191..42015
                     /locus_tag="PC512_000920"
     CDS             41191..42015
                     /locus_tag="PC512_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HDF2440690.1"
                     /translation="MKDYILYTILLLTGLFGTYAVIPLFKNLLINGNVLRPNYKKDMI
                     PVSMGIVFLPMIVINGIILAFFTTEFKDLAYIFMFMFGMISMFFAGILDDVIGNRDVS
                     GLKGHFKSLFKGSLTTGGFKALFGGFVGLIVSVAISKDIIDIIVNTLIIALSTNLMNL
                     LDLRPGRAIKAYLFIMVIIFLTLTGFVQVLPLLIVPNVLAYFNYDLKARAMMGDTGSN
                     VLGISIGMLISFGYPFNIRLGWLIFVVIMHIFTEKYSLTKIIEKNKLLNFIDKLGR"
     gene            42020..43087
                     /locus_tag="PC512_000921"
     CDS             42020..43087
                     /locus_tag="PC512_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3866 family protein"
                     /protein_id="HDF2440691.1"
                     /translation="MISKRVGIVESIVSQTETLDDIRVNINGEIQRAYNYPKISGTIN
                     IGDEVVLNTTAVELSLGTGGYHFVITNLNNIESTLTEGGHIMKLRYTPLQIKVDSVEE
                     QESIYHDKFANFKGLEGLSVVVGTLHSMLTPFAASFKRNNPNKKLVYIMTDGASLPIY
                     LSKNVDTLKEKKLIDSTITIGNAFGGDYECINIYTALITAKEILKADAVFVSMGPGIA
                     GTGTKYGFTGIEQGSILDAVKKLEGRAIAIPRISFADKRERHQGISHHSMTVFKEIVN
                     VNVDIPITIYDDEKLNFIKEQINLNGLDKKHNIIYIDNNKTKEDLDYFNLKVKSMGRN
                     YEQDEAFFKAASTAAYYLMEV"
     gene            43089..43625
                     /locus_tag="PC512_000922"
     CDS             43089..43625
                     /locus_tag="PC512_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HDF2440692.1"
                     /translation="MVLEEKTISSDRVYTGKVITLKVDTVEIPGQGYQKRELVEVGGA
                     VGIVAITDDNKVVLVKQFRKPIEKPIFEIPAGKLEKNESPKECAERELKEETGYSAKN
                     IKLIHKFFTSAGFSNEIMFVYLATGLTPGENNLDADEFLDVYEIELEEAYNMVLKNDV
                     EDAKTSIGLLLVKDMFKN"
     gene            43693..44298
                     /locus_tag="PC512_000923"
     CDS             43693..44298
                     /locus_tag="PC512_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
                     /protein_id="HDF2440693.1"
                     /translation="MRRTYRKNDFRELNRQIIIIGLLFMMSIVVGSYINKILPGSSNN
                     ILNNINPAVEYYNLNISIKDTVIQNLKSDAIFMGSIALLSLFVVTIPAVLVAFVLKGM
                     SIGYTINSCILALKFKSIKMILIILFKNLIIIPCAIILALISLSYFKEMVYEFKKKNR
                     KNMQFLIKRYILNIIIIIALSLGLQLILNTASIGIIKFLAK"
     gene            44310..45224
                     /locus_tag="PC512_000924"
     CDS             44310..45224
                     /locus_tag="PC512_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDF2440694.1"
                     /translation="MDIIEGYIDYIKDKKKLSENTVASYFMDIKKYMEYINQKSIKLV
                     DIVENDIISYLIKLEKDNVSIATIARMISSIKSFHDYLFLNHICTNNPAKDIKKPKIK
                     KENINILTEEEIERLLNFPKLTTPKLIRDKAIFEVLYGTGIKVSELVEMNIEDIDLDI
                     DYIYCNSCCKNQRVIPLCDITKLYLEKYLKEARPKMAVEGEKSLFVSSLGQRFTRQGL
                     WKVIKKYSNLANIDKNINPTMLRHSFAIHLLNEGANIAVVSKILGNVNLSSLQVYLNH
                     IDKNVRREIKEKHPRNDVDVELQKAEAK"
     gene            45266..46438
                     /locus_tag="PC512_000925"
     CDS             45266..46438
                     /locus_tag="PC512_000925"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HDF2440695.1"
                     /translation="MSRVIWIVIDSVGIGALPDAEKFGDSKDVSTLGNIFKEYPDIQI
                     PNMRNLGIGNIDGIDFFESIKEPIGCFGKCKEMSQGKDTTTGHWEMTGIIVDKPFKTF
                     EHGFSKEIIEEFEKKTGRKVVGNKPASGTVIIDEYGEHQIKTGDVIVYTSADSVFQIA
                     ANEEVIPLEELYNMCKIAREIMMGDNAVARVIARPFIGKKKGEFVRTSNRRDYSLDPF
                     EPTVLDNIKESGLDVLAVGKIEDIFNGKGITDAIHTKSNMDGVDETLNYMKQDNKGLI
                     YSNLVDFDSKYGHRRDPEGYKKALEEFDSRLPEIMANMREDDILIINADHGNDPTYKG
                     TDHTREYIPVMIYGNKIKKGFNLGVKDTFADIGATVADILNVKLPKHGSSFKEDLF"
     gene            46485..47297
                     /locus_tag="PC512_000926"
     CDS             46485..47297
                     /locus_tag="PC512_000926"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HDF2440696.1"
                     /translation="MFEKIAQSSKFINSKSDIKPKIGLILGSGLGDLANDIEDPVAIK
                     YSEIPNFPVSTVAGHAGQLVIGKLEGKEVIAMQGRFHYYEGYSQKEATFPVRVMKELG
                     VEILIVTNAAGGVNKEFKAGDLMLIRDHINFSGSNPLVGKNDDRFGARFPDMSDAYSS
                     KYVDVVKNCAKECNIDVKEGVYMFFSGPNYETPAEVRMAQILGADAVGMSTVPEVIVA
                     SHSNIGVIGISCITNMAAGILNQPLSHEEVIETTQKVKSEFMNLVKTTVKNL"
     gene            47501..48826
                     /locus_tag="PC512_000927"
     CDS             47501..48826
                     /locus_tag="PC512_000927"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HDF2440697.1"
                     /translation="MRMYDIIKKKRDNLELSKKEINYFIENYSKGDIPDYQASALLMS
                     IYLNKMNKQETVHLTEAMMNSGDMINLSEIDGIKVDKHSTGGVGDKTTIALIPLVASC
                     GAPVAKMSGRGLGHTGGTIDKLESIPGFSTEMEISKFIDSVNKSKIAVCGQSAKVAIA
                     DKKIYALRDVTATVDNISLISSSVMSKKLASGADAIVLDVKTGDGAFMKTLEESFELA
                     KSMVDIGTGMNRDTIGIVTDMDEPLGFAVGNSLEVIEAIETLKGNGPKDLVELCEVLG
                     AYMLVLSKVAHDFEDGVEKIRESIKSGTAIQKLKEFIENQGGNKDVVDDYSLFKKSKY
                     KYPVKSTKSGYISKIKAEDVGVSAMILGAGRETKDDILDLSAGIILEKKVGDYVNEGE
                     VLAYMYYNDEQKLSLAKGRFIDSYSIVDSKIEKNKLIYGIVTKEEIKKF"
     gene            49039..50118
                     /gene="mltG"
                     /locus_tag="PC512_000928"
     CDS             49039..50118
                     /gene="mltG"
                     /locus_tag="PC512_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HDF2440698.1"
                     /translation="MNFKENRLKIAVLIIVILIILAGIFVFIQIGPYDKNNKKDVIID
                     VPSGASVGKISDILYENKLIKNELLFKLLVKVSNKAPSIKSGTYLLNQSYSNNDIISL
                     LVSGKIYQDGIKVTIPEGATSKEIIAMLVSKNLGDKATFENLIKKPQEFYDKFPYLKE
                     DGITSLEGFLYPETYYFNSKKQSEEDILSEMLKVFDSKYTDKFKKKQKELNMTLQEVM
                     EMASIIEKEAVLDKDRPIIASVFYNRLKVGMPLQSDATIQYIFEERKKIVTYDDLKID
                     SPYNSYKNKGLPPTPISNPGIKSIEAALYPEKTDYLYFVAKIDGGNNYSTNYQDHLKY
                     VKEYKEARDKQSKDTKATNKENTKK"
     gene            50290..50964
                     /locus_tag="PC512_000929"
     CDS             50290..50964
                     /locus_tag="PC512_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HDF2440699.1"
                     /translation="MSNIVNDLVEDYIRVTLKEKEGFLKDLEIYAEENSVPIIHKEVS
                     DLLKVLLKVQKPKRILEVGCAIGYSSIFFATIIGKDADIITVERNEKMIEKAKENIKL
                     AGFDNNITILEGDAEEKLSQVQGEFDLIFIDAAKGQYKLFFDLVIDKLKDGGLLVSDN
                     ILYKGMVAHDDFVVRRKKTIVKRMRNYLDYICNCDYLSTSLVPIGDGVALSYKESKRG
                     DVDGIK"
     gene            50951..52198
                     /locus_tag="PC512_000930"
     CDS             50951..52198
                     /locus_tag="PC512_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HDF2440700.1"
                     /translation="MELNKVELLAPAGDLERLKIAITYGADAVYIGGEIFGMRSAAKN
                     FSKEDMAEGVAFAHERGKKVFVTVNIIPHNEDFLQLEDYLLELEEIGIDAVIIADPGV
                     LSVIKKVIPNMEIHLSTQANTTNYLSANFWYEHGIKRVVVARELSFDEISEIRAKTPL
                     DMDIEAFMHGAMCISYSGRCLISNYMTGRDANKGSCAQSCRWQYHLVEEKRPGEYFPI
                     YEDERGTFFFNSKDLCMIEYIPELIKSGITSLKIEGRMKTAYYVATVVRAYRMAIDEF
                     YRDPENWKFNPMWMEELKKGSHRHFTSGFYLNKPTTEDQNYQSASYVRNYDFIGIVRE
                     TEDEDGLIVVEQRNKMCVGDEIEVMGPYKETMFTKIEEMYNEEGEAIESAPHPRQIVK
                     LKLSVKVGKDYMLRKVIEEKVEE"
     gene            52270..53934
                     /locus_tag="PC512_000931"
     CDS             52270..53934
                     /locus_tag="PC512_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HDF2440701.1"
                     /translation="MSKKKTPFLKKVGKRSWCIFTIILIIYSVLIYRLVDIQVLKGDK
                     YKQSVESQSVEKVELNSGRGIIYDRNNKKLTDTSKSQVLIVEKEKLNNNYKILELIKK
                     ATKMNDLDIYKAVQEQLTRPIIQIQTKNIDKSMKKELEKNGIMVEEKTMRYAKDGLLS
                     HTIGYIKEDDKSGQSGIEKSMDSVLRNSNEKYISAFKAGDAGNEKSLNILKGSVKTVD
                     NKDKDRHLKTTIDYNIQKKLEQILNKEENPTAAIISEASTGEILAMCSRPNFDQNDIS
                     KSLKGKNGEFENRVIKATYPPGSVFKMVVLFSALENGVIDENYTYNCTGKTKVGNTNE
                     ILRCNKRDGHGFQNLRQAFSNSCNPAFLDIAMKLGKEKILKSAEKLHLFEKVDIGLDE
                     EKIREAPKNISIRNLAIGQENIEFTPLQINQMTQIIANNGTFKPLYLYKSLVDNNMNT
                     IKTYKSSKKEELISPYVCTQVKEYMKSVSRIGTAKDLKDIEGGCGVKTGTAQSSLNKK
                     AIDHGWITGFYPEERPKYVITVLVEGTQKGNKSATPIFKEICESIK"
     gene            complement(54031..54315)
                     /locus_tag="PC512_000932"
     CDS             complement(54031..54315)
                     /locus_tag="PC512_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012063608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF2440702.1"
                     /translation="MCNEISLLDILGTEANYVLDEVELKVQVGKLYEQLNKILTPRER
                     EIVQLRYGLTPYGYKTQREIAQKLDISRSYVSRIEKKALKKLEKELVQES"
     gene            complement(54338..55855)
                     /locus_tag="PC512_000933"
     CDS             complement(54338..55855)
                     /locus_tag="PC512_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDF2440703.1"
                     /translation="MSVAIYLRKSRADEEAEKQGEFETLSRHKSTLLKLAKEQNLDVI
                     EIKEELVSGESIIHRPKMLELLKEVEENKYDAVLVMDLDRLGRGDMKDQGIILETFKE
                     SKTKIITPRKTYDLTDEFDEEYSEFEAFMARKELKLISRRMQRGRIKSVEEGNFIGTS
                     APFGYDAVTTGRKERILVPNKDADVVRTIFDLYINEDMGCSKISKYLNNLGIKTATGA
                     NWYNSAITNIIKNKVYCGYIQWQKKDYKKSKNPNKIKTVKLRPKDEWIEAKGKHEPLI
                     SEITWKKAQNILKKNGHVSYGNQIKNPLAGIVICKNCGRPLVYRPYADHDYIICYHPG
                     CNKSSRFEFIEAAILKSLEDTVKKYQLKASDIDLDKNNKDSNIEFQKRVLKGLETELK
                     ELGKQKNKLYDLLERGIYDEDTFIERSNNISSRTEEIKDSIKTVKNRLSTVKKDNSKI
                     IEDIKTVLSLYHDSDSLGKNKLLKSVIDKAVYYKSKEQKLDSFELMVHLKLHEDQ"
     gene            complement(55980..56801)
                     /locus_tag="PC512_000934"
     CDS             complement(55980..56801)
                     /locus_tag="PC512_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HDF2440704.1"
                     /translation="MIISKKITAILVSFLIMISMVGCAPKESATEVAKKYLDSIKIKD
                     YEVAYNLLSKDSKESVSLEKFEEYQDTLFKLQTLKDYKLGEENKVEKYKYSNKEYTNL
                     VKIKETDTIKYITENKEDTANFDRYFIIEDNEYKLLWHKDFKRALSSNYVKIARSETE
                     KDEDKDYNKAAIDIKKAIEIDDKNPLAYYTQSYIYIELQRYDEALKSIDKYLEYLDKN
                     NEAYKIDASDAYNLRGVIFMSKSEFNKARESYNKALELNPDNEYAKTNLNDIKGL"
     gene            56992..58019
                     /locus_tag="PC512_000935"
                     /pseudo
     CDS             56992..58019
                     /locus_tag="PC512_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861148.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp26"
     gene            58091..58243
                     /locus_tag="PC512_000936"
     CDS             58091..58243
                     /locus_tag="PC512_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440705.1"
                     /translation="MDNFLFNVLASLTASVVVYLISKLFKKAKSHSRTKSDLRVEFKF
                     IFKSKK"
     repeat_region   58897..60045
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=58897..58925
                     /rpt_unit_seq="gttttatattaactaagtggtatgtaaag"
     gene            complement(60332..60556)
                     /locus_tag="PC512_000937"
     CDS             complement(60332..60556)
                     /locus_tag="PC512_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2440706.1"
                     /translation="MDVNQRIKYIRENMNSSQKELLEKTNINTSVMNRIESGERPTRE
                     DGLIIFAKIFGLYTDYILGLSDTEKLNIGN"
     gene            61235..61390
                     /locus_tag="PC512_000938"
     CDS             61235..61390
                     /locus_tag="PC512_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="regulator"
                     /protein_id="HDF2440707.1"
                     /translation="MALEVKIEVKIIKDVVILNITHWKKETSLLTVKIARGQGDLSYV
                     KYFTNES"
     gene            61636..61887
                     /locus_tag="PC512_000939"
     CDS             61636..61887
                     /locus_tag="PC512_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440708.1"
                     /translation="MSSYFITRGDVMKILQQFKPYKYDKEKNIEYDEKIIANQNTEVY
                     IVYPRISDEENRRRWEEFNEVAKEVAINIAMKKVETVES"
     gene            62529..62738
                     /locus_tag="PC512_000940"
     CDS             62529..62738
                     /locus_tag="PC512_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440709.1"
                     /translation="MMGLKLKRRYKNVLIYINIRTIININCKIKFIELYLTFNELKNK
                     LANNEKTTVINENNKAFSGLVDFSN"
     gene            complement(63107..63490)
                     /locus_tag="PC512_000941"
     CDS             complement(63107..63490)
                     /locus_tag="PC512_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440710.1"
                     /translation="MRKKFFIGILIVLIISVIAILNIKNDKNVFIGESENWKAKFVTT
                     EGHSKLEIKYKNSKDVVEQKFNYSYQFIDGEDAVVVVKNEILEAGQEKAIKIQRPGLY
                     SNRESSYKLIISWNGNEETINLKKK"
     gene            63617..63946
                     /locus_tag="PC512_000942"
     CDS             63617..63946
                     /locus_tag="PC512_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440711.1"
                     /translation="MNYRLKKSVTTILSLLIMTILLPTNASASKVEDSSMKVMYSEKQ
                     VTDMDKLYDMAKNGITDVKSSNEKGIIKNARTGESIYVDSISTTQLLEVKQSKNLTSK
                     IYSKTVF"
     gene            64143..64352
                     /locus_tag="PC512_000943"
     CDS             64143..64352
                     /locus_tag="PC512_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440712.1"
                     /translation="MHINQTGFISNGLGIKQQQKKEPTSNSFSYNAPSSWKPVGRDSV
                     QYNCGFESIATLVRGGSSWSFNFIV"
BASE COUNT        26068 a         6818 c        11652 g        20848 t
ORIGIN      
        1 agagttttat ttagacattt attacaaatc aaaatttatt acatattatt tataaaaaaa
       61 tctaaggagg aaataataat gaaaatatta gtattaaact gtgggagttc ttcattaaaa
      121 tatcaattaa tagatatgaa taatgaagaa gttttatgta taggattggt tgaaagaata
      181 ggaatagaag gttctatatt aaaacatgaa aaagcaggta gagatgataa atacgttgtt
      241 gaacaaccaa tgaaggacca caaagatgca atagcattag ttttagaagc tgttgctcat
      301 ccagaatttg gtgcagttaa agaaatgaaa gaaatagatg cagtaggaca tagagttgta
      361 catgctggag aaaaatttgc aacttcagta gtaataactc cagaagtaga agaagcttta
      421 aaagaatgta tagatttagc tccacttcat aatccagcaa acataatggg aatagatgct
      481 tgtaaagcta tacttccaga tgtaccaatg gtaggtgtat ttgatactgc tttccatcaa
      541 acaatgccta aatcttcata cttatatggt ttacctcatg agctatatac taaatatggg
      601 gtaagaagat atggattcca cggaacttct cataattatg tatctcagag agcagcagag
      661 atattaggaa aagatataaa agatttaaaa atagtaactt gtcacttagg aaatggtgct
      721 tctatagctg ctgttgatgg tggaaaatgt gtagatacat ctatgggatt cactccatta
      781 gaaggattaa taatgggaac tagatgtgga gatatagacc cagctatatt accattctta
      841 atgagaaaag aaggtttaga tgctgatgga ttggataaat taatgaataa agaatctgga
      901 gtatatggaa tgactggaat ttctagtgac ttcagagata tagaagatgc agctaaaaat
      961 ggagacgaaa gagctcaagc tacattagaa gcgtatgtta aaaaagtaca aaaatatata
     1021 ggcgcttatg ctgctgaaat gaatggattg gatgttgtag tatttactgc aggcgttggt
     1081 gaaaatggaa aggctataag agcagatatt gcttctaaca tggagttttt aggaatgaaa
     1141 ttagataaag aagctaatga tgttagagga aaagaaacag taatatctac tgctgattct
     1201 aaagtaaaaa tgcttttaat accaactaat gaagaattaa tgatagctag agatacatta
     1261 agattggtaa aataattaaa ttaaacctat gcctatcaag taaaaatact tgacaaacaa
     1321 atgctagatt tgtataataa atttggtgat atgttgaggt gaacttaatg aaagttagca
     1381 tagaaaaaat aaatagaaaa gaaactgaca aaatagactt gaatttttgt gaaaaaattg
     1441 atactattag ttattgtgat gagatttaca aattagtatc acctgtaaat ttaaaaggga
     1501 aagtgtcaaa gactaataaa ggtttgtatc tagatataga tgtcaatttt acaattgttg
     1561 acaattgttc aagatgtctt aaagaagtag aaataccact agagtattct atacaaggtt
     1621 ttttagtaaa agaagaagat tatgatgaag atgagtttga ggaatttgat ccttttatat
     1681 tcgatggtga agaaatcgac cttattgata taatagaaca gacattagat tttaatgtac
     1741 ctcataaagt tctttgtagt gaaaactgta aaggtctttg tcaagtatgc ggggcaaact
     1801 taaatgaaga agagtgttct tgcagtgaaa ttacaaacga tgaggaatac atagatcctc
     1861 gttttgctaa attaaaagat ttatttaatt aaattttgac taaggaggtg gcgtaaatgg
     1921 cagtaccaaa gcgtaaaacg tctaaatcaa acacaaaaat gagaagagca gctaactcaa
     1981 agatggaagc aacaggattt gtaagttgcc cacaatgtca tgagccaaaa ttaccacata
     2041 gagtgtgtcc agactgtgga tattataaag gtaaagaagt tgtgtctaag taatagcttc
     2101 taaaaagcat gtagagtata ctctacatgt tttttttgta catataaaaa aataagatga
     2161 tttactagag aaaataagtg gattttatgc atattaaaaa atagaaaaat aataatataa
     2221 gtattgaaaa tttttgtgtg ttactatata ctactattag tagctggtac taattacagc
     2281 tataaaattt ggagggaaca tgaaaaagaa aagtaaagcc caaagacaaa aagagcttat
     2341 agatatgcta aagacagatc ctttttatac tgatgaagaa ttatcaagtc tgtttgatgt
     2401 aagtatacag accataagat tagatagaat gagtctaaac ataccagagc taagagaaag
     2461 agtcaaatca atagcagaaa ctcagagttc aaaagtaaag actttaggag taaaggaaat
     2521 tacaggagaa atcattgatt tatctgtagg gcgattaggt atatctatgt tagaagttac
     2581 acaggacatg atttactcta agactaatac tttaaaagat acgtatattt tttctctagc
     2641 agattcattg gcaatggcta taatagatgc acctaaggtt attatgagag ttgcaaatgt
     2701 aaaaagtttt aagttgatag aacaacaaga tagacttata gcaaaagcag aagtgtatag
     2761 aaatatagat aaaaagcatt atgtaaaagt tgttatcaac aataaagccc aagagcaaat
     2821 atttagagga aagtttatct ttgaagaatt agattaggag ggaaattatg aaaatagtaa
     2881 ttgatggaat gggtggagat aatgcaccta aatctaatgt agaaggcgca gtaaatgcta
     2941 taaaagaata tcaggttgat ttaataatca caggagataa agatttactt gaaaaggaat
     3001 tttcaaatta tgaatttgat agaaataaat tagagatagt tcatactact gagattatag
     3061 aaaacgaaga taaaccagta aaggctataa gaagtaaaaa agattcatct atggtagtag
     3121 cattaaatct tgtaaaagaa ggaaaggcag atgctataat atcagctgga aatacaggag
     3181 ccttacttgc tggtggatta tttgttgttg gtagaataaa aggaatcgat agaccttgct
     3241 tatgttcagc aataccaaat gtaaagcgag gaatgacact tatagcagac tgtggcgcaa
     3301 atgcagattg taaacctaag aatctagttg aatttgcagc tatgagtaat atttattcaa
     3361 gaaaagtttt aggtcttgaa aatcctaagg tagcattagc aaatgttgga ctagaagaag
     3421 gcaaaggcaa tgatttagtc aaaaggtcat atgaagaaat taaaaaatta gatttaaatt
     3481 ttatagggaa tgtagaagct agagaagtta taaatgcata cacagatata atcatatgtg
     3541 atggatttac aggtaatata ttacttaaat ctgctgaagg tgtagcactt tcagttatga
     3601 gtcttataaa ggaaactttt atggccagta caaaaagtaa aataggagca ttacttataa
     3661 aggatgattt aagaaaatta aaaagtttta tagattattc tgagtatggg ggagctccac
     3721 ttttaggtct aaatggagga gttataaaag ctcatggtag ttctgatgct aaagctataa
     3781 aaaatgctat aaatcaagga ataaaatttt caaagggaaa agtcgttgaa gatattaacc
     3841 aatttataag caaatacaat gaagaaaata aaaataacga agatgaataa actcgttttg
     3901 gaggtttaat atataatgaa tacaaaggct ggaatattag gagtaggaag ttatctacct
     3961 gagcaatcat atgataattt tcacttcgaa aaaataatgg atacatcaga tgagtggata
     4021 agtactagaa ctggtattaa ggaaagaaga tttgccaaag agtctgaagc aacttctgac
     4081 ttagcatcta aagctgcctt aaaagctata gaatgtgcaa agttaaacgt agaggatata
     4141 gagctgatta tattagctac aattactcct gatatgtctt tgccttcaac tgcatgtata
     4201 gtacaagatg caataggagc agtaaatgct actgcatttg atatatcagc agcttgttct
     4261 ggatttgtat atggagtaac tattgcaaag caatttgtgg aaacaggttg ctataaaaat
     4321 gtgcttgtaa taggagcaga aacttgttct aagtttttaa attatgatga tagaacaaca
     4381 gcagtattgt ttggagatgg agctggagca gctgttattg gccctgtaaa tgagggtgga
     4441 atactgtcta cacatatggg ctctgatggt aaaggaaaag attgtttaaa agtacctgct
     4501 ggaggttcaa gacttaaggc aagtaaagag actgtagaag ctaatctaca tacaatagaa
     4561 atggcaggta gtgatgtgtt taaatttgca gttagaaaga tggcagaaac ttctttaaga
     4621 gctcttgaaa aagcaaatct aaatacaact gatatagact acttagtgcc acatcaagct
     4681 aatataagaa tcatacaagc ttcttctaag agattagagc ttgatatgaa aaaagtttat
     4741 gtaaatatag acaaatatgg aaatatgtct gctgcatcta taccagtagc attagatgaa
     4801 gcttatagag aaggtaaaat taaaaagggt gataatgtag ttttagttgg ctttggtgga
     4861 ggtctaactt ggggggcttc agttgtcaag tggactttat agtataaaat atctaaaatg
     4921 atttaattaa caaaattaaa cttatacaca aaataaagtt gattaataat aaaaagttta
     4981 cttttatgat ttcaagtgaa ggagaattgt atgaataaaa tttgcaaaat attaaatata
     5041 aaatacccag ttatccaagg gggaatggca tgggtagcta ctgcatcatt agcaagtgct
     5101 gtatctaatg caggaggact tggcataata gcagcaggaa acgcaccaaa agaagctata
     5161 aagaaagaaa ttgttgagtg taaaaaatta acagataaac cttttggagt aaatgtaatg
     5221 cttatgtcgc catttgttga tgatataatt gatttgatta tagaagaaaa agttcaagtt
     5281 attactactg gtgctggaaa tcctgcaaag tatatggata gattaaagga agctggaaca
     5341 aaggttattc ctgtagtacc tacaatagct ttggcacaaa gaatggaaaa gctaggagct
     5401 acagcagtaa tagcagaagg tactgaaggt ggaggacata taggagaact tactactatg
     5461 gtcttagttc cacaagttgc tgatgctgta aacatacctg taatagctgc tggaggaatt
     5521 gtagatggta gaggaattgc agcatcattt gcattaggtg ccagtgcagt tcaagtagga
     5581 actagattta tttgcagtga agagtgttct gtccattcaa actataaaaa cttagtacta
     5641 aaagcaaaag atagagatgc aattgtaaca ggaagaagta ctggtcatcc agtaagaaca
     5701 ttaaaaaata aactatcaaa agaattttta aagatggaac aaaatggagc tactcctgaa
     5761 gaactggata aaaaaggtac aggagcttta agatttgcaa cagtagatgg agacatagaa
     5821 aaaggttcat ttatggcagg tcaaagtgct gctatggtaa aagaaataac accttgtaag
     5881 gaaattatag aggctatggt aaatcaagca agagagatta tgccagcaat agaactgtaa
     5941 atcaggagga gcaagatggg aaaagttgca ctagtattcc ctggtcaagg agctcaatat
     6001 gtaggtatgg ccaaggattt atatgaaaat aatactgttg ctaaaagtgt aatagatgag
     6061 gctagtgatg ccttaaatat ggatttaaaa aaccttatgt ttaatggaaa tgaagaagaa
     6121 ctttctaaaa ctgaaaacac tcaacctgct atggttacac atagtgtagc tgtattaaaa
     6181 gcagtacaag cccaagtaga tttaaaatat agtgcatgtt taggtttatc tttaggagag
     6241 tatagtgcat tggttgcagc agatgcaatt gactttaaag atgctgtatg cttggtcaaa
     6301 aaaagaggta agtttatgca ggatacagtt ccaacaggtg ttggagctat ggcagcaatt
     6361 ttaggtctag atagaagtat attagaaaat gtagttaaag atatacaagg aggtattgtg
     6421 gaagtagcaa attataattc tcctggtcaa atagttatat ctggtgaaaa tgaaaagata
     6481 gaagaagcaa tggtgaaatg caaagaagca ggagcaaaaa gagctgttaa attaaatgta
     6541 agtggacctt ttcactcatc aatgctaaga gaagctggtg taaaattggc cagtgaatta
     6601 gaaaaagtta acataactaa acctaaagtt gatgtggtgg caaatgtaaa tgcagattac
     6661 tataaaaacg aaggtaaaga cctgcttata aaacaagtaa gttcatctgt tctttgggaa
     6721 gattctatag aaagactttt aaatgatgga tatgatactt ttatagaaat gggacctgga
     6781 aaaactttaa aagcatttat taagaaaata gcttccaata aaaaagcaaa tgtcaatatt
     6841 tataatatag atggtataga ttctcttaat gaatttgtac aaaattatag aaatggagag
     6901 atataatgat aaatcttaca ggacaagtag cagttgttac tggtggctct aggggtatag
     6961 gaaaagaaat agcaaaaaaa ctagcatctt ttggagctga tgtagtaatc aattatactt
     7021 ctaaagaaga tgaagcacta aaaactaaaa atgaaataga aagtatgggg gtaaagtgta
     7081 cctctataaa atgtgatgtg tctaaatttg atgaagtgaa tcaaatgata gattctgttg
     7141 taagcgaatt tggaaaaatt gatatattgg ttaataatgc aggcataact aaagatggtc
     7201 tgcttatgag aatgaaagaa gaagattttg atagagttat agatataaac ttaaaaggtg
     7261 tctttaattg tacaaaagca gttactaaac ctatgatgaa aaagaagtat ggaagaataa
     7321 taaatatgac ttcagtagtt ggaattatgg gtaatgcagg gcaaactaat tattgtgcat
     7381 caaaagcagg tgtaattgga tttacaaaag cttctgcaag agagttagca tcaagaaaca
     7441 taaatataaa tgcagtagca cctggattta tagaaacaga tatgactaaa gtactaagtg
     7501 atgatgtaaa agaatcaaca ctagcaaaca taccaaagaa atcttatggt aaaccagaag
     7561 atgtagccaa tgccgtagca tttttagtta gtgacatgtc aagttatata acaggacaag
     7621 taataaatgt agatggtgga atggtaatgc aataataatt taaaaagtag agaaatctat
     7681 taaaataaaa aattttagga ggtacacaat gtttaataaa gttgtagaaa taataataga
     7741 gcaattagga gtagaagata aagaaataac tatggaaaca tcattaatga aggatttaga
     7801 agcagattca ttagatgcag tagaaataat aatggcactt gaagatgaat ttggtataga
     7861 aataccagat acagaagcag aaaacttcaa atctatagga gatatagtta agtatataga
     7921 agctaataaa tagtcgagct ttaaaaaagt ggaggtatcc gatgaataaa agagtagtaa
     7981 taacaggact tggatgtgtt acgccgttgg gaacaggaaa agaagagttc tggagtaata
     8041 taaaatctgg agtatctggt atagataaaa taactaattt tgatgctagc acatatcaaa
     8101 ctcagatagc aggagaagtt aagaattttc atccagaaga atatataagt aaaaaagaat
     8161 tgaagagatt agataaattt gctcaatttg caatagtatc tgctaaatta gcagttgaag
     8221 atgcaaatct tgatttagat aaagttgata gagaacgttt tggtgttata ataggttctg
     8281 gaataggtgg agttgaagct atagaaactc aacataaaat tcttttggaa aaaggaaata
     8341 aaagagtaag ttcacttttt gtacctatga tgataggaaa tatggcagct ggtcaagttt
     8401 caatattttt aggagcaaaa gggcctaaca ctaatgtatg tacagcttgt gcatcaggaa
     8461 ctcattcaat aggtgatgct tttaaggtaa ttcaaagagg tgatgcagac atcatggtag
     8521 cagggggttc tgaagctgct gtaacaggtc ttgcttttgc tggattctgt aacatgaagg
     8581 ctatgtcaac tagaaatgat gaccctaaaa ctgcatcaag accatttgat aaagacagag
     8641 atggttttgt aatgggagaa ggagcaggta ttgttatctt agaagactta gaacatgctt
     8701 tagcaagagg cgctaaaata tatgcagaag tagttggata tggtttaact gctgatgcat
     8761 accatatgac aactccagct gaaaatggag agggagcagc taggtctatg aatatggctt
     8821 tgaaagatgg aaatgttcca ttagaagaag tagattatat aaatgctcat ggaacttcaa
     8881 cttattacaa tgatttatat gaaactatgg ctataaaaac tgtatttgga gaaaaggcat
     8941 atgacttatg tgtgtcatca acaaaatcta tgactggtca cttattagga gcatcaggtg
     9001 ctatagaggc tgttgtttgt gctatgagta tagaagatag ttttgtgcct ccaactataa
     9061 acatacaaga agttggtgaa gatttggatt tagattatgt tccaaatcaa ggtaaagaaa
     9121 aaaatattag atatgcacta tcaaattctt taggatttgg tgggcataat gctacaatag
     9181 tactaaaaaa atatgtataa ataaatatta aatataaaac taaaaaacaa gcacttgttt
     9241 taactgtata aatttatatt agcttaaatt taaagtctcc taaattattt taggagactt
     9301 ttttattaag atttaagtct agcatatgtt gtaaatcatt ttgatatatt gtattattaa
     9361 ttattaagag gttatttata tatgtaagtt ttcattctac aatatacaaa aggaggacta
     9421 aaattttgaa ttttagacta ccaaagaaaa ggttacccaa aaagataatt tttatatgta
     9481 taatacttat tagtattatt ttgtttataa agcatgacca aaatggattg aaagaaagag
     9541 aaattataaa taagggaaaa tatatgtctg aaagccttgt ggcagataag gagtatgatg
     9601 aagcaaaaaa agtggttaag acttctttcg aatctattcc agaaaaaaaa tacaataaag
     9661 tatataatga agtttgggat atgttaaaga ctatttcata tgttccagat ggaacgaaga
     9721 tagtcattga ttctttagaa aagatgagag aatcagatgt gaaattatct gatgaatgta
     9781 gatttaatat agaaaaaaga ttagcatcag tgtatataat ggataataat tattctaagg
     9841 cagtagattt aactgtaaag tctataaagt tggctgagaa attggggaat aattatgaaa
     9901 aagcaagact agatgttgat ttggcgagca tatttttaaa gataggtggc tatgaaacag
     9961 gagagaaatt aataaaggat tcttttaaaa tagatattga tgaaggtgaa aaaaatggaa
    10021 tggttagatt atatgctatt ataaatctag cagaaatata tgtagaagag ggcgaatatg
    10081 ataaagctat tgaaataagt agcaggataa aagattataa aaagtttgta aatacggata
    10141 attacaatga ttttgatata atggcctcta taatgcagtc aaatgcgtat gtgggcaaaa
    10201 ataatataca aaaggcaaag acttttttag aaaaagctga ttatcttata aaatcagata
    10261 gaacagttta tatattagat aaagatatgt actattatat ggcaatggga aacttagaat
    10321 ataaaagcga aaattataat tctgcaatag ataattataa aaaaagttta gagatatcta
    10381 ctaaaagaaa gttaacccag gagaaaataa aaaatttaaa taagatatta aatatatatg
    10441 aaaaacaagg aaatatagaa tctttaaatg agtatcaaaa gatgttaata aatgaatata
    10501 aagagaacaa aagtataaga gattcagaga ctagtttcta tataattgat aaagtatcaa
    10561 acgaaagtaa gctatttgaa aaaactaaaa aagaaataaa atattataaa atattattta
    10621 cagtaatttt aattgctata ttagggtcta cttttttata caaccgattg aagtatttta
    10681 aagcacaaaa tttacatgat ggtcttacaa atgtttataa tagaaaaagt tttgatatta
    10741 tgtatgaaaa gtacagagag aaagatgata attttgcact tgtgatgata gatattgata
    10801 atttcaagct cataaatgat aattatggac ataaatttgg tgacactgtt ataaagggaa
    10861 taacaaatac catttgtgtt atgttagaac aagatgataa agtctttagg tacggaggag
    10921 aagaattttc tgtattaata agaaataaat ctggtgatga agtagcagat ataattgaca
    10981 gtataagggt tgcaattgca aataaaaagt ggaatgatga tgtgactgtg actataagtg
    11041 caggtgtagc tcatgtttca gatagcaaag atgtactaga agaagctgat aaaaatttat
    11101 ataaagcaaa acaacttggt agaaataaag tagtatataa gtaattatat actatataaa
    11161 taagaggtat aaatatgaaa caatcaatag ctatagtaac tgataaaata actaaactat
    11221 catctttctt agaagaaaat atacgtttgg ttttaggtaa ttatattgat ataaaccact
    11281 attatctgga agttttaaaa gagaatgata aaatacaagg tgattttgta ctagtaatga
    11341 atgatgatag attaaacagt atgagaaagc atttagtaca agatagtaag attatagtga
    11401 taaggagaac acttaaagaa aatgaaatat atggattatt ttcaatacca aatggaactg
    11461 aagtattggt tgtaaatgat acaaaagaaa ctaccttaga aacgataagc ttattttaca
    11521 aaataggagt aaaaaattta aagtttactc catatattga aggaaaaatt tataaaaata
    11581 tagacatagc tataacgcct ggagtaaagg gaaaagtacc aagttatata aataaagtaa
    11641 tcgaccttgg aaatagatat attgatatat ctacctttat agaaataata aatggtctta
    11701 gaatagatgt taaagaaata cgtaaaaatt taatggcata ttctgagagt ttaataagtt
    11761 tagataatgg agttaaagat aattataggc aactgttttt aaaaatagaa gaacaagatg
    11821 ttatattgaa tctatcaaaa gatggaataa tatttacttc agcagatggt ataataaaca
    11881 catttaataa agaagcttta aaaattttag gtataaatga aaatccacaa ggcaaaaaca
    11941 tagaagatat catttctgaa gatttaaata ttttacttga agacaaagaa ataattgatg
    12001 aagtggtatt tacaaataaa aaatatataa atgtaaataa aaaaagtatt ttttctatgg
    12061 ggaataaagc tgggatatat tataacttac aagaaataac gtatataaaa aaattagaac
    12121 aaaatcttac taataaatta agagaacaag gtcagatagc aagatataca tttaaagata
    12181 taaaaactaa aaataaaaat atggtaaagt gtgtagaatt ggctaaaaaa atatctaaat
    12241 cagaactttc tgtattaata ataggagaaa gtggtactgg taaagaatta ttatcacaat
    12301 caattcataa tgcttccaat agaagtaatc aaccgtttat agcagttaat tgtgcagcag
    12361 ttccagatag tctattagaa agtcaactgt ttggatatga aaaaggctct tttacaggag
    12421 ctttaagaga aggaaaaaag ggtctatttg aacttgctaa taatggaact atatttctgg
    12481 atgaaattgg agatatgcct ccattgctac agacaaagtt actaagggta ttacaagaaa
    12541 agcaggttat gcctataggt tcccataatg ttataaacat agatgttagg gtcatagcag
    12601 caacaaacaa aaacttacta aagatgatta gagaaggaaa atttagagag gacctgtatt
    12661 atagactaaa tgtattgcca atagatgtac catcattgag gaatagaaaa gaagatataa
    12721 taacacttat gaatttcttt ttgaaaaaca atataagact ttcgccagaa gttataacta
    12781 ttttagaaaa atataattgg ccaggaaata taagagagtt acaaaatgtt gcttcttatg
    12841 taagtctaat gtgtgatagt atggttttta gagatgactt accaccatat ataagggtag
    12901 aatgtgctaa caattatgaa gatggatttg gttatacaag aaaagaattt gaggaaatac
    12961 tgaggattct atatgaaaga agagagtcat cctctggaat tggaagaggg tttataatcg
    13021 aaaagcttat acaggaaggt attgagattt ctgaaagcaa agttagaaag gtgctatctt
    13081 atttaagtga atgtggatac atatcatcta aatctggtag aggaggaagt caaataacct
    13141 cagaggggat aaaactttat aataatataa attaagctaa gtatttgata ttgaaatcac
    13201 atattttgaa tttagatatt taaataataa taaactttta tatttataga gattaattta
    13261 tattatgtca gaaagaatat tgtaatttat aattaaatat taataggttt ttaaaatagg
    13321 attagatagg taataggtta agttagaata acccattacc tatttttatt tgtaagaaaa
    13381 gtgtacatag aattagaagt aaaaaataca actaataaaa ctattgaaaa tactagataa
    13441 ataataaata aaaataatta tagattttgg catacatatt gctaattata gagataagac
    13501 gacaaaataa ttgggaggtt taatgatgaa atacaaaaca acagggactt gtgctacaga
    13561 aattgaattt gaagtaaaag aaaataaagt tacaaatgta aactttatag gtggatgtga
    13621 tggaaattta aaagggctaa aagtattagt tgaaggcatg aatatagaag atgtaataca
    13681 aaagttaaaa ggaatagagt gtaaaacaaa gccaacatct tgcccagacc aactgtctct
    13741 agcattggaa aattatatga atataaagta atacataaaa caatcgatta gttaggagtt
    13801 taattatgaa accaataata gggattttag gaaatttaat aataatggaa aatggtatgt
    13861 ttccaggtct tgaaaggtca tatgtaaata atgattatat aaatgcagtg ctaaaaggag
    13921 gaggtagtcc agtaataatt cctgtaaata cagataaaga agttataaaa aaacagattg
    13981 aaatggttga tggagtctta atatctgggg gatgggatat caatcctcaa ctgtatggag
    14041 aagaaacaag agaagaaacg acatttatat atccagaagt ggatgaattt gatttaattg
    14101 caataagtat agcattagaa cttaaaaagc ctatattagg tgtatgtagg ggactacaaa
    14161 ttttaaatgt aagtttagga ggaactttat atcaagataa taatcttata gaaggaagtt
    14221 atataaaaca tacacaatct tctaaaagac atgtagctac tcataaagtt gatgttaaag
    14281 aaggaagtat tttagaggga attttaggaa aacaattact tacaaatagt tatcatcatc
    14341 aaagtgtcaa tcagcttgga aaaggattaa aagccatagc atactcaaaa gatggtataa
    14401 tagaagctat tgagaaagag gatgaaaatt ttgtagtagg agtacagtgg catccagaaa
    14461 tgatggtaga ttactgtgat aaaatggaaa aactatttaa atattttata aatatttgtt
    14521 caaatttata atataccttg gggggattga acatgaacga aaagaacaaa atgggattaa
    14581 taagtattat acttttaggt attaatgcag tagtaggagc tggagttttt ctattaccag
    14641 gagatgcaat gaaatcattt ggtgtagcaa gtatatttgt atatatattt gatatgttgt
    14701 tagttttatc tatggcattc tgttttgctg aggttgcagg taaattcaat aaaaatggtg
    14761 ctgcctatgt atatacaaaa gaagcttttg gagatttttg tggttttgaa gtaggtctta
    14821 tgaaatgggt aataggatgt atttcttggg gagctttaat agtaggtttt cctacatcat
    14881 tatcagcagt atgggctcca gcaggtgaac cacatataca aaaaattata attgtagtca
    14941 tgatagttgg gcttacaatt ataaacttat taggtgtatc tctatcaaaa attgtacaaa
    15001 atgttataac tgtaggtaaa ctaattccat taatactatt tataggaata ggtatatttt
    15061 ttataaaagg agttaatttt acttcttcaa caatggtacc tccaggagct ggagcaacag
    15121 agtttggagc agcagcactt ttaatgtttt attcatttac aggatttgaa tctatagcag
    15181 ttgcagcaga agatatggag aatccacaaa aaaatatacc aatagcaatt ataagtgtaa
    15241 tagtaattgc atcaataata tatatattaa atcaagttgt atgtgttggt atactaggag
    15301 attcgttatc tagtacatct acaccagtgg cagatgctgc aagaatatgc tttggaaata
    15361 tgggagctgg attggttacc tttggaacct tggtttctgt tggtggaatt tgtatgtgtg
    15421 gtgcttttgt aaatccaaga agctgtgtag ctttagctga tgataaaatg ttaccgagaa
    15481 tatttgcaag aaaagataaa aaaggtacac catatgtagc gataatagct actatgctaa
    15541 tcactatacc aatagctcta tctggaagtt ttgctgaatt agcagcaata agtgcagttg
    15601 ctagattcat acaatacata ccaacatctt tatccgtatt agtgtttaga aagaaaagac
    15661 cagaattagt aggtactttt aaaactcctt ttggagcagt gattcctcta attgctgtat
    15721 gtgttggaac atggttatta ttccaagcat ctatgcatca attaattatg ggattaggag
    15781 ctttggcaat tggagtacca ttatacttta taatgaagtc ttataataga aaagtctatg
    15841 atgaaaattt aaagaaaata gtttaattat gttataacaa tttattgagt taaaattaga
    15901 cattggcata aaattaaata caaataagta tctacaaggc tatattaaaa tattattaat
    15961 tttttatttt aatatagcct tatattgtta tcaataaatg aaaaatattg taacaataga
    16021 agaacaatag tattatgttt atagacaaaa aacttattag gaggtaaatt tatgccaaca
    16081 ataacattaa aaaatggtgt agacgtactt attagagaag gtgtaagaga agatgctcaa
    16141 agcattatag atttttataa tgaagtgggt ggagaaactc attttctgtc atttggaaag
    16201 gatgaatata aaatatcttt ggaggaacaa gaaaatgcta tagaatcagc aaaagcatcc
    16261 gataattctg ttaaactgat tgcatttata gatggtgaaa tagttgggat tgcaacgatt
    16321 gattctaatc aaaaagcaaa aggaaagcat gttggagtat taggaattgt tgtaaaagaa
    16381 aaatattggg gaattggatt gggtaaaagg cttatgttag accttataga atggtgtaaa
    16441 tcaaatggaa taaccaagaa gataactctt gtcactaatg aagaaaatta taatgctata
    16501 ggattataca aaaaagttgg atttgaagta gaaagcatac taaagaaaga atgttattat
    16561 aatggtgttt atactgattt aataggaatg tcacttttat tgggaatata attagtgtac
    16621 attttatctc gaaaaaagta tattaagtat ggtataatta aaaaagaata taacttaata
    16681 taattttgga ggacgaatta tgaaaaatct gtgtaaaata tcagatgatt atttaaacag
    16741 caagcttaag tatttaaagt tattatcaaa acaatatcca agtatatcaa aagcaagtac
    16801 agaaataata aatttagagg ctatattaaa tcttccaaag ggaacagagc attttataac
    16861 agatgtacat ggtgaatatg aaccatttgt acatgtatta aaaaatggtt ctggtgtaat
    16921 aaagagaaaa atagaagaat tgttttcaaa tacaataaga gacagcgaaa aaaaaatgtt
    16981 agcaactctt gtatattatc ctgaacaaaa gttagaccta ataattaagc aagaggaaaa
    17041 tatagatgat ttttatagaa taaatattta tagacttata gaactttgta aatatgcttc
    17101 tagcaaatat actaggtcta aagttagaaa actgttacca gaaaatttta aatacataat
    17161 agaagaactt ttgcatgagc atgttaaaag tgaacataaa gaagagtatt ataaaagtat
    17221 agttgaaaca atagttgaca taggaatagc taaggagttt ataattgcta tttctacagt
    17281 tatacaaaaa ttggttgtag atagacttca tgtaatagga gatatttatg atagaggtcc
    17341 aagaccagat ataattgtcg ataagcttat tgaacatcat tgtgtagata ttcaatgggg
    17401 aaatcatgat atattgtgga tgggtgcagc ctcaggtgaa aaaacttgta tagcaaatgc
    17461 actgaggata tcagctagat atgcgaattt agacattgta gaagacatat atggaataaa
    17521 tctattgcct ttagccactt ttgctataga aatgtataaa gatgaccctt gtaaagaatt
    17581 tattccaaag gttaatgacc aaagtgtaac aacaacagaa aagtctttaa tggcaaaaat
    17641 gcacaaagca ataagtataa ttcaatttaa gcttgaaggt gaggttatca gacgaagacc
    17701 tgaatttgaa atggaacata gactcttgct taatatgata aactatgatg aaggtacgat
    17761 taatttaaaa ggtaaaacat ataaattaaa agatacttat ttacctacaa tagacaaaaa
    17821 agacccatat aaattaacta tggaagaaag aaatgttatt gataaattag tatcttcatt
    17881 tagaggtagt gaaaaattac aaaaacatgt ttcatttttg ttttctaaag gaagtatata
    17941 tttaaaggct aactcaaatt tactgattca tggatgtgta ccgttaaatg aagatggaag
    18001 ctttatgtct atgaatataa tgggaaaaga gtataaaggt aaggctctta tggataagat
    18061 ggagtctcta gcaagagaag gatttttctt taaagataag gcagaagaaa aactgtatgg
    18121 catggatatt atgtggtatt tatggactgg gaaatgttca tcattatttg gtaaagatga
    18181 tatgactaca tttgaaagat actttatagc tgaaaaagag actcataaag aaaataagaa
    18241 cccatatttt aaacttagag aaaatgagat ggcttgtaaa agattatttg aagaatttga
    18301 tttagaactt gatgaatctc atataataaa tggtcatgtt cctgtggaga gtaaaaatgg
    18361 agagagccca ataaaagcta atggtaaaat tctcgttata gatggtggtt tttctagggc
    18421 ttaccaaaaa actactggta tagctggata cactttgata tacaattcta gaactttgca
    18481 attagtatcg catgaaccat ttaattctgc tgaagaagcc attgcaaatg aaagtgatat
    18541 cttatcgaca actgttgtag tagagcataa ggcaaagaga aaaatggtga gagatactga
    18601 tgaaggagta aagatacaag aggaaataga agatttaaaa ctacttttaa tggcttataa
    18661 gaaagggcta ataaaagaaa tgtagatgtt atagaggcac ttcatgattg aagtgtcttt
    18721 ttgttaatac ttattaaata tattataaag attaataata gtagtttata ttatacttac
    18781 taagtgaatc caagataaat gggttcactt tttttattta taaacattat taaaaaaata
    18841 tagatgtttt ggttatattc cttgtccttt ataaatagaa ttatataaac aaaggaggag
    18901 gacaagagat gaataaactt tctgatgaaa taataaactc tctttctaca actataagag
    18961 aaaaggtaga aaaagtctca aacaataatc tgaacataga agaaattagg ttacgctcac
    19021 aaaaaccatt gatactaaat gcaaactcta aagattattt ttacaatcaa aaaactatga
    19081 cacttgattt aaatcaacaa aactcatatg tagtaacaag agaagatgta gagcaaactt
    19141 ttcaaataat atgtaaatat tcaatacatt catttatgga tgacataaaa aaaggattca
    19201 taactttgag aggaggtcat agagtagggt tagttggaaa agcaatagta gaagatggac
    19261 aagtcaaaaa tataaagcat atatcatctt taaatataag ggtatcaagg gaaattattg
    19321 gatgctcgga taagatttta agtcatatca taaagggaaa aaatcagatt aataatactt
    19381 tgataatatc accacctcaa tgtggaaaaa caactttaat aagagatata gtaagaaatt
    19441 taagtaatgg taatgaagat tatggattta aaggtttaaa agtggcttta gtagatgagc
    19501 gtaatgagat agcaggagct tatctaggtg ttccacaaat ggatgtggga ataaggactg
    19561 atataataga aacttgccca aaagacttgg gtattacaat gcttttaagg tctatgtcac
    19621 caaatgttat tgtgacagat gaaattggaa gtgaaaaaga aataaaggca ttatacacag
    19681 cattaaatgg aggtatagga ttaataacta ctgtgcatgg agattcaata gaggatatac
    19741 aaaatagaaa agaattaaat agacttctgg ataaagagtt atttaaaaag gttataattc
    19801 tttctgcaaa aagaggagca ggaacaattg aaaaaattta tgatttagaa gaaaagagat
    19861 ggtattttgc aaattaaaat aattattata gctttcttga taggaagtag ttatttgata
    19921 ggtgaacaaa tatacaaaac ttatactcgt agacataaac aattaaacga tttaataaga
    19981 gttttagaaa ttttgaggat ggatttatct tttggacttt atacattaga agaaatcttt
    20041 aataggatag gtggaaataa agagttttgt ttttggaaat ttttctatca aatatcagaa
    20101 ggacttcaca atgaacaaag taaaactttg gaaataataa tatcagaaaa tattgatgtc
    20161 ttaagtaaag aaacttatct aggcaataaa gaaattgagg aactgaaaaa tctaatactt
    20221 actttaggga aaagcgatat agagtcacaa caaagaatga tagatttatc tatagaaaat
    20281 ttgaaaaaac aaacctatga gacaaaggaa gatataaaca aaaaaggcgt attgtataaa
    20341 aaattagtga cattcatagg tataggtata tgtattatat tgatttaata tggggaggtt
    20401 tattatggaa atatcattga tattaaaggt tgcaggtgtc ggtattctaa tatcagtatt
    20461 gaatatgata ttggaaaaaa cagatagaaa agattgggca ggtcttacta cattagcagg
    20521 tgtaataatc gtattgggta tggtaataac agaaataagt gacttgttta atactgtaag
    20581 aacaatgttt caactttact aaagaggagg gagtaatttg gaaataatgc aattaatagg
    20641 aattgcaatc atttcaacta cactctgttt agtaattaaa aaagatagac cagagatagc
    20701 aaatttcata gctataataa ctggagtaat aatactattg tcagttatgt ttaagctaaa
    20761 ttttatagta gatagtatac aagatttggc taacaaggct aacatcccga ctatgtatat
    20821 atcattaata ataaaattaa ttgggatagc atacttaatg gaatttgcga tacaactttg
    20881 taaagattgt ggggaaggaa acattgcttc aaaactagaa tttggaggta aaataatagt
    20941 tatgtcaatg tctttcccta tacttttgtc cattgtagaa atggtggtga atataattcc
    21001 atagatgtgt atcttggaat gaatataagt atattagaga gcttttgttg tattgaggtt
    21061 tatagagtga agagaggcat ggttgcttat gaaaaaaaga tttttaccaa tgattatagg
    21121 ttttttattt actttctttt ttgtaaatat ctttgctatt atgatatttg ctaatgaagt
    21181 accaagtagt gaagataaag aatatggtga aacaaaaaat agcatagata agtatataga
    21241 tggtcaatta gacaagctag atataaatga gattcaagac tatataaata aagaaatagt
    21301 tattaatgat gttaatttaa aatcatttgt aaaagattta attagtggag aaaaaaatat
    21361 cttagattta ttcaataaag atggattgaa gatattgatg tttgatgaat ttaaagcaag
    21421 tttaaaggta gtagcagtaa ttttggtact ggctctgtta tcatctattt taaagagtct
    21481 ggaaaactct ttttcatcag gtgcagtaag tcaaatagca acatatataa tatttatcac
    21541 aatggtatca cttacactta ttggttttaa agatgtatta cagatttgct atgatgcaat
    21601 agaccatact gtaggtctta tgcaagttat aatgccaata ttaataacat ttttactttt
    21661 aattggattc ccaataacgt cgactacttt gaatcctatc ttcataggag gagtaacatt
    21721 tataaatgta ttttttaaaa attttctatt tgtatctatt actgttgcat ttggaatttt
    21781 aataataaac aatttatcaa aaaatataag gctaaagaga tttttctcct ttgtaaaaca
    21841 aataaattat gtttctattg gagctatgtt tactgtttac ttaggtcttg tatccataca
    21901 aggattgtat gtaaccagtt ttgataaatt cagtgtaaag actgctaaat ttgctatagg
    21961 taattttatt cctgttgtag gtggatttgt atctgactct gtggatattt tattatcttc
    22021 atctcagctt ataaaaaata tatttggagg aatagggctt atcttacttg ttggaatttg
    22081 cttacttcca gtaataaaaa ttttatcagt aatagtagtg tacaaattag cagcaataat
    22141 tgtagagcct gttggagagg atggaatatc taatttttta aatgaagtgg caaatttaat
    22201 gataataatg ctagcatcag taattgctat aacagtaatg ttctttgtaa ctgtagctat
    22261 cttgacctcg ataagtgtcg taagtcaagg gtaatttata tatcagtgaa aaataattac
    22321 atttaatcta atgtttttag agaggaggat gctatgttag agggcataaa ggcatggata
    22381 gttagtgttt tgataggagc atttatagta aatatagtag atatgatttt accaagttct
    22441 aagataaaac cttatgtcaa cctagtttta aactttatgt ttgtatttat tgtaataact
    22501 ccagtagtag gatttttttc aaaagatatg agtttagaag atagaatatt aaaatctatg
    22561 ggaaactaca acaagcagta tgtagatagt acaaatgctt tggcaaaaga gactggaaat
    22621 aatagtctat ccaagggata tgaggatggg ttaaaagaag tacttaaatt aaaacttgat
    22681 gaatatggtt atgatttaga agatatagag cttaatgggg caaatataaa taatataaaa
    22741 ataaaagaaa agaataatag tgcaaaaagt aataacagtt ccaatgaaga aaataaaaat
    22801 aatagtacta aaagagagga agaaaacata aactctaatg acaaagaaaa ttctaaacaa
    22861 gtcttcaaaa aaggtacaga gtatgggttg aacctaaatg aagaaaaatt aaaaaacgac
    22921 ttaataaagg tgctggatgt ttctatagaa gatatacaaa ttgataaata ggagttggga
    22981 gaatgttgaa aaacttaaat gacaaagata agagaaaggt atattcacta ataactatag
    23041 caggaatatg tgtggtttca ttagtattat tatcttgttt tcctagtagc aaaagcgata
    23101 aacaagttgg aaaaacagag actaataaaa atgctgaaaa gcaagtcact aaagaacaag
    23161 aaaaagatga tttagagtca aaattaacag caatactatc taaaattgat ggtgcaggag
    23221 acgttgatgt aatggttaca tttgaatcaa gtgaagaaat acaacctgct tttaattcaa
    23281 ataatacaac agaaacaaca gaggaaaaag atgcacaagg tggagaaaga acagttacga
    23341 cttctagtga aaataaaaca atgataactt caaattcaag tgaccctgta gttataaaaa
    23401 ctacagagcc aaagataaag ggagtgatag tggtagcaag tggagcaagt gacccaagtg
    23461 ttaaagagac actttatagt gcagtacaaa catcattaca agtagctggt catcaagtag
    23521 aaatatattc taaataaata catataaccg gggggataaa tgaatgaagt ttaattataa
    23581 gggaagagga tttgtaataa taactttaac tgcaatgtta gtggtagtag gaacagtgaa
    23641 ttatcaacta agtaagaaat ctttattaga aacatcaaaa gagtttaagg catatgaaga
    23701 agcacagttg caaaaaaata ctgatgatag ttatagtagt aagacagagg attctagtaa
    23761 tgtagataaa caaggtggta aggaaagtgc tgatattgat atagtcgata gcaaagctag
    23821 taaagtaaaa gaaaaggcaa ctgagacaag taaggaaata aaagctcaat tatcatcaga
    23881 gaaaaatatg aaaaaggcat cttatatttt agatatgaaa atgaatagag aaaaacaaag
    23941 aaatgagtta gttcaagatt taaatgaaat gataaataat ccatctacaa cagaagaatc
    24001 tagaaaagaa gcttctaata tgaaattaaa tatagttaaa attcaagaaa aagaacttca
    24061 aatagaaaac cttttgagta caaaaggata tgaagaagcg ttagtttata taagcgataa
    24121 caaagttaat gtagttgtaa atgaagctaa attagaaaag aaagatgcag caaaaatatt
    24181 tgatttagtt gcagaacaag ccaatgtgaa gtatgaaaat attaaactta caaataataa
    24241 tagtaataag taaagtataa acctcagaat taactgaggt tattttcttg caaagtagac
    24301 ttgtatttgg tattattata cttataaaaa tagttcctta aaatcaggag gtaagtttta
    24361 atatggaaga taataaattt ggacaagtaa aaatatctaa tgatgtaata gctacaatag
    24421 ctggtttagc agcattagaa gttgaaggca tagaaactac agcaacatta acagataagt
    24481 tgttaaaaaa taatggagta aaaatacaaa tcgaagaaga ggatgttaat ttagatgtaa
    24541 tggttacgat aaagtatgga atgtcaatac cagatacagc ttttaaagtt caagaaaatg
    24601 taaaaaatac tgttgagaca atgacaggac tgaaggtttc tcaagtaaat atacacattc
    24661 aaggaatcag ctttaagaag gataaagttg ataaagaaga agcaaaagca actaagaaaa
    24721 attaatatta gccctctgaa aagtcagagg gttttttgct ggtaattgat tttatatgga
    24781 taattaaact taaaggagaa ttttgattga tgaaaaaaga tagggcacaa aagagtacaa
    24841 caagagaata tataatgaaa cttatatacc aaataaatat taataaagaa gattttgaaa
    24901 ctttagaaga taaagtagat aattttttaa aagataattc agaacatatt ataaatagat
    24961 ataaagaact tgcacttcaa tactcaaaaa atacaaattt aaagttagaa gatactgaaa
    25021 ttgaagatgt tatagacaaa aaatatataa atacagtatg caaagcattg aaagaaaatc
    25081 atgacaaaat agatgagtta ataaataagc atgctaaaaa ctggacagta gatagaatgc
    25141 caaaggtaga tgtttctata cttagattgt ctgtgtgtga aatactttat ttagacactc
    25201 ctaataaagt atcaataaat gaagcagtag aacttgcaaa aatatattgt gatgataagt
    25261 ctcctaaatt tataaatggt atattgggaa gtgttgttga tgaaattggg aaataatata
    25321 ataattggaa ttgatactag ctgctatact acttctatag cagctatctc tttagataag
    25381 aaagttatat tcaatgaaaa aataatgtta gaagtaaggg ataattcaaa aggtttaagg
    25441 caaagtgaag ctgtatttca acatatcaat aatttaggga ttcttagtga taggataaaa
    25501 tcttttaaag ataagtttaa tgtagaagga gtttgctcat caaaaaaacc gagacctgtt
    25561 gaaaactcat atatgcctgt attcaatgta ggtcataatt ttggaaaatt attgtctagt
    25621 atatatggtt gtagatttta tgagactact catcaagaga atcatattga agcaagttta
    25681 ttaaatagta aattaaaaaa taataataaa tttatttctg ttcatatgtc tggtggtact
    25741 acagagatac ttttaacaag caaacaagat agtcatcaca atgtatgtga tactaattta
    25801 ggtaaaattg ccaaaataag tattaaaaaa gatgataaaa gtaagttata caataatttt
    25861 ggatataata tagatataat tggaggaagt aaagatatta gctttggtca acttatagat
    25921 agagtaggaa ttaagcttgg atataaattt ccttcaggaa agtatttgga tgaaaatgct
    25981 ttaaattgta atcttaaaat agaaagtggt ctgaaaactt ctgtaagaga tgggtatatg
    26041 aatttatcag gattagaaaa tcaggtaaat aagattataa atgataatgg agataatact
    26101 aatcaaaaag aatatatatc taaattagta ttagattcag tagttagaaa tatgtttaaa
    26161 tctctagtgt atttatgtga aacttataat gtaaatgaag tagtatttgc tggtggagtt
    26221 tctgcaagta agtatattct tagagaatta agcatgaagt taagaaaaaa gcatatagaa
    26281 gcttatttta cagaaccaca atattcaact gataatgctg tcgggtgtgc tataatagga
    26341 ttgaataact ttttaggaga aagagtatga aactaagagc tttagatata agtgaagcaa
    26401 actcatatat taaaagaatt ttaataaacg acccaatact ttctaatctt aaagttaaag
    26461 gagaaatttc taattttaag gttcatagta gtgggaatgt atatttatca cttaaagatg
    26521 aaacatcaaa gttaaactgt gtaattttta aaagtaattt taatcgcaat ttaaaattag
    26581 ataatggtgt aaaaattata gctaatggat atatatcagt ctatgaaaga gatggtgcgt
    26641 atcaattata cattaatgaa attgaaatag agggaatagg aaatttgcac atagagttta
    26701 atagattaaa ggaaaaactt aataaagaag gattatttga ccctaaatac aagataccta
    26761 tacctaaaat gccaaactca attggcgtta taacatctcc aacaggtgct gttataagag
    26821 atataataaa tgtaataaaa agaagatatc cgaaagttaa tataaagctt tatccagtaa
    26881 cggttcaagg agataaatca gctgaagaaa tctgtgaagc aattagattt ttcaatcata
    26941 tgaagaatgt tgatacactt atagttggta gaggtggggg ttcaatagaa gaactttggt
    27001 cttttaatga tgaaatggta gcaagagagg tttttaattc tcaaattccg ataatatcag
    27061 cagttgggca tgaaacggat tttactattt gtgactttgt gtctgatatg agagccccaa
    27121 cgccatcagc agcagctgag attgctactc catcattgga tgatataaac tataaacttg
    27181 gaaacataaa aagtaggatg agtaagtctc ttacaaatca aatagagcta gaccaatata
    27241 ggttagaaac agtatttaat aagataaata actatttaga ttcgtacaca ataaaagata
    27301 aagttataca attagacaaa atatatgata aaataatttt tggaatagaa aataatttaa
    27361 aattagaaga tgaaaaatta gtaaaaattg gagcattact ccataattta agtccattag
    27421 ctactatgga tagaggttat agtataactc aaaaaaatgg aaaagtaata aatagtataa
    27481 aaggattaaa aataaaggat agtatagata tagtattaaa agatggaaat ttagaatgta
    27541 tgatagataa aattgaaaat aaagagggat agtatgaatt taacctacga agaagcttat
    27601 aaaagattag aaagtatttt aagtgaatta gaatctaaaa atgctagctt ggatgaatct
    27661 ttaagcctat atgaagaagg tataagcctt tataaacatt gtaataagct tttagatgat
    27721 gctaaattga aaataagtaa atttaatcaa ttgggaatag aagaagactt taaaatagag
    27781 gaggaataaa attggaattt aaacaatgtc taaaagaaaa agcaagtttt gtagaaaaag
    27841 tacttaaaga atatatgcct aaagaagaag ggtatcaaaa aactgttatt gaagctatga
    27901 actatagctt aagtgctgga ggtaaaagat taagaccaat acttacattg gaggcttgta
    27961 aaatagttgg aggtaatgaa gatgaagcta ttccttttgc tattgcaatt gaaatgatac
    28021 atacatattc actaatacat gatgatttgc cagctcttga taatgatgat ttaagaagag
    28081 gaagaccaac aaatcataaa gtatatggag aagctatggg gattttagca ggagatgctt
    28141 tgttaaacta tgcttttgaa gtaatgcttg caggctcaat caataaagaa aatccagaaa
    28201 agtatctaaa agctataaat gaaattgcca aaggtgctgg tatatatgga atgataggtg
    28261 gtcaagtagt agatgtagaa agcgaaaata aacaaattga aaaagaaaaa ttagattata
    28321 tacatatgaa taaaactgct gcaatgatgg taggctgtat gagagcagga gctactatag
    28381 gtggagcaaa ttctgaacaa atggaagaaa taactaaata tgcaaaaaat atcggattat
    28441 cattccagat agtagatgat atactagaca tagtaggaga tgaagctaag ttaggtaaaa
    28501 aggttggaag tgatatagaa aatcataagt caacataccc atctctttta ggtttagata
    28561 aatctaaaga aattgcacat aatttgattg atgaagcaaa gaaaagtata gaaaaattat
    28621 ctgatgatgt agatttttta aagggattgg ctgaatatat aatagataga gaatactaaa
    28681 atatacagct aaaatcgagg agggaaaaat ggattttttt tcggagattt ttaacaatgg
    28741 ggctttggga ataagtctga ttgcttgttt cttagcacaa tttataaaaa tatttactgg
    28801 taaggaaaaa agaattgagt tatcaagaat acttatttca ggaggtatgc ctagttccca
    28861 tagttctttt gttacaagtt tagctacagt ggtaggtatt gaaaaagggt ttaattctac
    28921 tgattttgct ataattaccg tgcttgcctt aattataatg tatgatgcag caggtgttag
    28981 acgggctgtt ggtaaacaag ctactatatt aaatcaaatg gtggcagata tacagcatgg
    29041 aaagcatata gagcagaaga aattaaaaga attaataggt catacaccac tagaagtttg
    29101 gtttggagct ttacttggaa tagtaacagc tttaatattg atgtaaattg aaaatttaca
    29161 gaataaaggt gaggataata tgtataaata tttagataaa gtaaattctc caaaggatat
    29221 aaaaaatatg agtatagaag aaatggattt acttgcaaag gatataagaa agttcttagt
    29281 aaaatctgtt tcaaagacag gaggacactt agcttctaat ctaggagtgg ttgagttaac
    29341 attagcactt cataaagtat ttgatagccc taaagataag attgtatggg atgtagggca
    29401 tcaatcttat gttcataaaa tagttactgg aagaaaagat tgttttgtat ctttgagaca
    29461 gtttaatgga ctaagtggtt ttccaaagga gaatgaaagt cctcatgata tttttgatac
    29521 aggacatagc agtacatcta tttctatagc tacaggtatt gcctgtgcta gggatataaa
    29581 aaaagaaaac tatagtgtta tatctgtgat aggagatggt tctataacag gaggtatggc
    29641 acttgaagct ttaaatcaat taggatatat agataccaat atgatagtaa tccttaatga
    29701 taatgagatg tccatagata aaaatgttgg aggaatgtct aaatatctgt caagtattat
    29761 aagaaactca acagttgaga aaatgacaga tgaagttgat aaaattttaa atgttacaca
    29821 aacaggtgaa attttatcta agactgcaca tagatttaaa gataaactaa tgtatagctt
    29881 ttctcctcag gactgttcat tttttgattc attaggtata agatattatg gacctataga
    29941 tggccataat actaaagaac taatagatat attgagaaaa gctaaacaca aaaaagggcc
    30001 tgttctttta catgtaatta cgaaaaaagg aaaagggtac agatttgcag aagaacaacc
    30061 tgataaatat catggagtat caaagtttga tataaagaca ggtgttacat ctgcaaaagt
    30121 taagtctatg tcaattagtg ttggagaaaa acttgttgat atggctaata gtaatgaaaa
    30181 tatagtagca ataacagctg caatgccatc tggtacaggg ttaaacctgt ttgaaagtgc
    30241 atatccaaaa agatattatg atgttggtat agctgaacaa catgcaacag gatttgcagc
    30301 aggtcttgca aaaaatggta tgaaacctta ctttgctgtg tactcatcat ttttgcaaag
    30361 ggcatatgac caagttattc atgatgtatg cataacaaaa aagccagtta cttttcttat
    30421 agatagagct ggattagttg gaaatgatgg agaaactcat catggtatgt ttgatttaag
    30481 ttacttaaat tctattccaa atattgtagt aatggctcca aaagacacaa gagagatgga
    30541 gcttatgatg gatttgtcat taaaattaga ttgtccacta gcaattagat acccaagagg
    30601 aagtagttat tacctagata agggagagta tggagagatt gtactgggta aatatgaggt
    30661 attagatgac ggtcaagata cagtcatact ttgtattgga agtatggtaa aacatgcttt
    30721 agaggctaaa gaaatattat caagagaagg aataaatccg acaatagtta atgctagatt
    30781 cttaaagcca attgatgaag gtatgttaaa agcattatta aaaaatcata aaaatgtagt
    30841 tactatagag gataatattg taactggagg atttggaagt agaataaata agtttattat
    30901 agataatgaa tataacgtaa atatacttaa tatagcaata ccagaagaat ttgtaaaaca
    30961 tggcaatata gatgaattat atgactttgt aggattatcg ccaaaaagta ttgctgataa
    31021 gataaggaaa ttagttattg agtaaaaatc taatgtagat attgtaaatt aaaatttata
    31081 taaaatatag aatttatcaa ttagaataaa tatcaagtgt gttacttcaa gctactttag
    31141 ttatcattaa agtagctttt aacagaaagg taattgtatg aaaaaaagaa tagatttatt
    31201 attagtagaa caagggtact ttgaaagtag agaaagagcc aaaaaagcaa taatggctgg
    31261 attggttttt gttgataatc aaaggtgtga taaggctggt acagaagtaa aagaagattg
    31321 tagtatagaa gtaaaaggaa atccaatacc atatgtcagt agaggtggtt taaagcttga
    31381 aaaagcaatg aaaaactttg atttgactat tgatggaaag gtatgtatgg atataggggc
    31441 atccacaggt ggttttacag attgtatgct caaaaatgga gcaataaaag tattttctat
    31501 agatgttggt tatggtcaac ttgcatggaa attgagacaa gatgataggg ttgtgtgtat
    31561 ggaaagaacc aatataagaa atgtgacaat agaagataca aagcagtttg ctgattttgc
    31621 gtcaattgat gtgtctttta tatcgttaaa gttagtactt ccaaaggcaa aggagttagt
    31681 acgtcatgat ggggaagttg tcgctttaat taaacctcaa tttgaagcag gaagagaaaa
    31741 agtaggtaaa aaaggagtag ttagagaaaa atctacacat atagaagtta taaaaatgat
    31801 ttctgatttc tcagtcgaaa atggatttga gattttaggg ttagattttt ctcctattaa
    31861 aggtcctgaa ggtaatatag aatatctaat tcatttgaga aatggaaatg aaggatatga
    31921 atttgatggt gagacataca ataacaaaat agtagaagtt gttgaagctt ctcataattt
    31981 agacaaatag gttaaaaggg ggcttagatt tgatcctcga attatatatg aaaaattgtg
    32041 ccttagttga agaactaagg ttgaatattg ataaaaactt aaatatactt acaggtgaaa
    32101 ctggttcagg aaaatctata ataatagatg cacttggact ttgtttaggt gataaatatg
    32161 ataggtcttt tttaagaaaa ggaacagata agggacttgt tgaggctgta tttttttcag
    32221 acaatagata tcttaaaaaa atattagaag aaaatgatat aagtatggaa gatgataatt
    32281 tattggtaat aactaggttg atatactcag atggtaagag tactgctaga gtaaatggaa
    32341 ggactgttaa agtgtctctt cttaaagaaa ttgcatctac acttatagat atacatggtc
    32401 aacatcaaaa tcaagctttg tttaataaag atactcattt aaaatttcta gacctttttg
    32461 gagaaaatga attggaagag tttaaaattg cttataaaaa tgtgtaccat aagtatagtg
    32521 aagtaaaaaa agctttaaat tgcttgacag aaaataaaga tgagatgcaa attcaacgag
    32581 aaatagattt attaagattt caaataaatg aaattgaagc tgcaaatcta aataagaatg
    32641 aatatgaaga tttattaaaa caaagagaag tttatagaaa tagtgaaaag atatataata
    32701 atctaaattc gagttatagc aagttacata atggtgagta taatgttatt gacctaatag
    32761 gtcttgcatc taaggaactt aatgacatat ctaaatatga cagtgtttta agtgaatata
    32821 gtgatactgt agaaagaatc atgtatgagt tacaagacat atctggtgag ataagaaatt
    32881 acaaagataa tatagacttt gaaccttatg agctagagca gattgagctt agaatcgacg
    32941 agattaataa cttaagaaga aaatatggag acagtataga tgatatattt gagtattatg
    33001 gaaaaattaa agatagatta gatgaaatat taaacagaga tgaaagagtt gaacagttaa
    33061 gaagcaaact gatgaatata gaagaagatt taaaaataaa agccagtaaa ttgactaaag
    33121 caagaataga agtagcaact actttagaaa aaatacttct tgatgaatta aaaagcttaa
    33181 atatgaaaaa tgtaatgttc aaggttaatt ttgaaaaagg tccatttact ttagatggag
    33241 tagatgatat tgaatttatg atatctttta acttaggaga agatattaag cctatatata
    33301 aagttgcatc aggtggtgag atgtccagat ttatgttagc gtttaaaacc atattggctg
    33361 atatagatga tattgataca ttagtgtttg acgagataga tactggaata agtgggatag
    33421 cagcacagat agttggtgag aaattgagtg atatagcaaa gaaaaaacag ataatatgta
    33481 taactcattt acctcaaatt gctgcaaatg cagacactca ttattgtata gagaaagata
    33541 cttcaaataa taggacgttt accaatgtta gtaagttaaa tgaatctcaa cgaaaaaatg
    33601 aaattgccag acttatagca ggtaacaata taacagaaaa aactattgaa catgcaagtg
    33661 aaattattga gttggctaaa aaatgttagt gaaaaacaag cattttaata ggtgtaaaga
    33721 atttttatag aaatgcttta catctatttt ttatgatgaa attattttaa aatatctagt
    33781 gcctatattg aagaaaagta ggtttgaaaa tggaatgaac tttgtataaa tttgtaactt
    33841 tgaaatttct aaatgcttaa gtataatatt atttattaag gtagtagtga ggggaggcat
    33901 aaaatgaata aaaaagatac tatgcactta atttttataa ttgtaatttt tattttatta
    33961 tggtatattg tggtagcagt aagtgagatt aataaaaata ttgaaagttg tagtaacaaa
    34021 ttagattatt tgtcacaaga gcttatgagt actaagtcgg atattagtaa tactataaat
    34081 gaagaaatgt caaaaagcta tataacaaaa agtattgact taaaagtgaa aaaaatcgag
    34141 aaaaaagaat gtattattga tatagatgtt caattaagta aacttggaaa aaatggaaaa
    34201 gtatttttta tgtataaaga agatagtgat aaatggaatg aaactgagat gacaaaacat
    34261 ggagaattat catatgcatg tgaaattaag ataaatacag gaagtgaata tgactataaa
    34321 gtagttacaa gtggagctat atctgaaagt tctgatgtgc aaaaattgac taaatctgat
    34381 tatatgcctg aacaacccat atttaattct gggataagag ataatagaga atactttatt
    34441 gaaatagtag aaaatagtaa tcttttcaat catgagagtg aaaagtcaaa aaataaagtt
    34501 tatgataata ttagattaga aaaagtagat attattgtaa atgaaggaaa aaaagacact
    34561 atatacaaag ccaaattagc tgaaggctta gatgatggca aaactaataa ttcaaataga
    34621 aatcaagtga attatgaagt aagttttcct aaaagggata ttgatgacat aatttatatt
    34681 aaagctaaac ttacatacaa taatggagta gaatatacaa aggatataac tgaagatata
    34741 actatgggat tacaagattt agaaaaataa atacatattt aaataaatat tcaaatagat
    34801 ttgttcaata aaatagagta taaataaaac tgtagtagtt ttacttatac tctattaaaa
    34861 aattataatt ttaattccat atatctagcc ccttcaattg gattataagt ataaggttct
    34921 atatcataaa aaccaaactt ttcgtataat ccttgtgcac ttttcatgct tggaagagta
    34981 tctaatctca tgtgtgtata tccaaatttt ttagcttctt caatgatttc ttccaatagt
    35041 atttttccta tttttaatcc tctaaattga tttcttacat ataatctttt taattcacat
    35101 attttacctt caagtttttt taaagcaaca caacctgcca aattttcatc aacaaatgcc
    35161 aatatcaatg agcctgaagg ttttttatat tttcctggaa gtgtttttaa ttcattatta
    35221 aagtcttgaa aacataagtc tatatttaga gaatttgaat attcagtaaa tagaagtttt
    35281 acgttttcaa ggttttctaa atctttttct tcaacaaatt gtaaagttat attttgagcc
    35341 attttatccg ccattatata cacatgttta tataatgact tcacctcctt gatatatgta
    35401 tatttttctt aatatcaatt agattttaat accattactt tttcaccacc atagtcaagc
    35461 tctccattaa actcaaatcc aaaatcttta taaagcttaa tagccatttt attgtcttcg
    35521 aatatactaa gatatagttc atcacagtta tattcatttt taagatgatt tacaagaaaa
    35581 tctaatgatg cttttccata tcctttacct tgatattttg aatcaatcat aaatctatca
    35641 agccaaactc tatcatcttc taaacgacca tacatagcaa atcctattaa agaattttca
    35701 tcatatattc caacaggtac ccaagctgtt ataaatttag attcagcaat agaaagtgca
    35761 ttgctttcta tataatctaa ctgactttta tctacagaca aactaactaa atcatgccaa
    35821 ttatttatgt ctgcaattct tacatttaat ttcaagatat taccgccctt caaacttttt
    35881 gttacaatct aatactatca tattatgtat taaaaatcac ttattaagat tttaaataaa
    35941 ctttttaaat gaataaattc tcaggaaaaa ggaattataa atacataata atacagcata
    36001 ggagtagatg gatatatgaa caaaataaat aaaaatttca aaaatatttg gataatatta
    36061 ggagctgtat cgatttttac catggttata atttttaata aaaattgtaa tgttaataaa
    36121 gagactcaaa tagaagcttt tacaattaag aatcatgata aaaaatttgt atatcctatg
    36181 ggaaatataa ttggagtaaa agcaaataca gatggtgtat tggtcttagg atatgaggaa
    36241 gaggatgtag actatattgg aggcatacaa atcggtgata atatagtaaa aatagataat
    36301 aaaaggataa aaaatagtca agatgtatca gagattttga ataagattaa aaaaagtaaa
    36361 gttgaagtga cttttgagag aaaaaataag tataaaacag aagtaataga gactaaaaaa
    36421 gaaaatggca agtataaact tggattatgg gtaagagata aaatatctgg aattggaact
    36481 atgacttttt acgaccctag tatggaaaag ttcaaagcaa ttggtcatgc cataaaagat
    36541 tcggatacta atgaactatt aaagataaag caaggatata tatataagcc agaacaatta
    36601 aaaatagtaa aagctagtaa tgaaaaagta ggtaaaataa aaggagattt taatgacagc
    36661 aatttaatgg gtaatttctc aaataattca gagttaggta taagtggtaa tattacagaa
    36721 aaccataata aagagtttaa tgtagcaaat aaagaaaagc aattaataga agttggaaga
    36781 ccgcaagatg taaaaatagg aggtgcagta attctttttg aggataaaaa caaaaatata
    36841 acaagctatg atataaaaat agaaagtata gtatatgata aaggaaatta tagagatatg
    36901 gtaataaaag tagtagatga caagttattg gaatacacag gaggtatcgt acaggggatg
    36961 agtggagctc caataataca aaataataaa attattggtg caataactca tgtttttaga
    37021 gataatccga aaaaaggata tggtattttt atagatgaaa tgataaaatt gtaggtgagg
    37081 cattaaaaaa ttttattatt ttatcaatta tctaggagga atataatttt ggagtgtcga
    37141 atatgcttta gagtagataa ttaggaagca attgtgtaaa aagtttagtt ttctgtaata
    37201 agaagatgtt ttttaatggg gggattttta gtggaaaaaa tcaaaatagt tttagcagat
    37261 gacaataagg atttttgtca ggtattaaaa gagtatttgt ctaatgaaga tgatatcgat
    37321 atattaggca tagctaagga tggaattgaa gcattagact tagtaaaaaa gacacaaccg
    37381 gacttattaa tactagatgt aataatgcca catctagatg gattaggtgt aattgaaaaa
    37441 ttgaatacta tggatatacc taaaatgcca aaaataatag tactatcagc agtaggtcaa
    37501 gataagataa ctcaaagcgc aataaatcta ggagcagatt actacatagt aaagccattt
    37561 gattttgttg tgtttataaa cagaattaga gagctagttt ctaatagagt tacacaagtt
    37621 gagccaaaac ctagaccagt tcaagagact caaatgacta gaagtgattt tgttaagaat
    37681 gtaggaaata tagagacaga aatcacaaat ataatacatg aaataggagt accagctcat
    37741 ataaaaggat atttatattt aagagaagca ataaaaatgg ttattgataa tgttgagctt
    37801 ttaggtgcag taacaaaaga gttatatcca agtatagcta aaaaattcaa tacaacacca
    37861 agtagagttg aaagagcaat aagacatgca atagaggttg catggagtag aggaaaagtt
    37921 gacacaataa atcaattatt tggatatacg gtacacaata ctaaaggaaa accaactaat
    37981 tcagaattta tagcaatgat tgctgataaa ttaagactag aacatagtat ggttaaataa
    38041 acaagacata aaaagtaagg ctttttaatt aaggcattgg ctataaatgc gtattacaag
    38101 cagcgaaacg gtataaccac tagggttata ccgtttcgct attttaataa atataaaaat
    38161 tttatttatt atttgcttac tatatcaata taataatttt attatactat ggatatagta
    38221 tgtgtcttta caagttgtaa actgacagtg gtttattttt taatataaat attgactttg
    38281 atgcaggtaa actttgtatt tttaagcgta ttatggaata tgttaaataa aaaaatgatg
    38341 aaatatagta ttgtaaatgc caaagatgca aaacaaactt aaaacattta ttttattgtt
    38401 aagtaatgct ataatataat gtgattttaa taatgatagt ggaggtttaa atatgagagt
    38461 cgaggcccct ataaaagtag atcgaaaaac caaaaaactt gctaaaagag ttgaaagtgg
    38521 ggaaatagca gttataaatc atatagacat agatgaagtt gctgcaaact ctttagtaga
    38581 agctaaaata aaacttgtca taaatgcggc tccttctata agtggtaggt atcccaataa
    38641 aggtccaggg atattaactg aaaataatat actaataatt gataatgttg gagaagagtt
    38701 atttgaagaa ttaaaagaag gagaaactat agaagttgta gatggaaaga tatatagaaa
    38761 aggaaaattt ttaggtgcag gagaagtttt agacaagtat gaggtttcac accaaataaa
    38821 ggctgcctat gagaatttag ctgtagaatt ggatagattt atagataata ctatagatta
    38881 tgctaaaaaa gaaaaaggat ttatacttgg agaagtagaa attccaaaag tgaaaactaa
    38941 ttatgctaat aaacatgtat tgatagttgt aagaggtcag gactacaaag aagatttaag
    39001 tactatgctt tcttatatag aagaggtaaa gccagtattg gttggtgttg atggaggagc
    39061 agacgcttta attgagtttg gatatactcc agatgtgatt gtaggtgata tggatagtgt
    39121 aagtgatgaa gctttaaaaa aggctagtga aatagtagta catgcttata cagatggaag
    39181 agcaccaggt cttaaaaggg ttgaggaatt aggcttagat gcagttgtat ttcctgcacc
    39241 aggaactagt gaagatatag ctatgcttat cgcttatgag tataaggctg agttaatagt
    39301 agcagttggt acacattcaa atatgattga ttttcttgaa aaaggaagaa aaggtatggc
    39361 aagtactttt ttagttagac taaaaatagg ttcaaagctt atagatgcta aaggcgttaa
    39421 tttgttatac agaagtaaat taaaaataaa gtacatatgg gcattaatag caacagcatt
    39481 atttcctgtg ttggtagttg catcattgtc accaggagtt caacagttca tacaactaat
    39541 gcaattaaag tttagagtat tattacagat gtaaatttta ggaggataaa tatgcatatt
    39601 aatatgaaat attatatagt cactataggg gctatattta tagctttggg tataggcatg
    39661 ttagtaggat ttaatttaaa taataatcaa caattaagtg aacaacaagc aaacataata
    39721 aatgatttgg atgataagtt tgatatctta aaagaaaaaa atgataaact tgacagtgac
    39781 ttagcaagtg taaatagaga ttatgaagag gcagttaatt ttataaataa aaatgtagat
    39841 aagattttag ctggttcgct gaatggtaaa agtataggaa taatatctgc taatgaaaat
    39901 gacgattata caaaaaatat agaagacata ataaataaat ctaatggaag cattgcattt
    39961 aatataatat taaaagaaaa cataacaaat ccagaaaagt taaaggaaat gtcaactaaa
    40021 ctaggtacag atgtaaaaaa tgcaaatgat gcagttaatt atataattga cactcttaaa
    40081 aaggaagatg caagtgacat tttaacatat cttcaagaac tagatgtaat aaagtttaat
    40141 tttattggag atacatatct aaaatatgat tccgttgtaa tagctggtgg aaatgatgca
    40201 aaagacagta caaaacagtt tgaaaaaata gaaaaatttg tagtttcaaa acttaaatca
    40261 gagaataaat atttagtaga agttcaaaat acaggagtta aaacttctta tgtagaacta
    40321 tattctaaaa acaaagttgc aactatagac aatattgatg aaggtatagg aagtatatct
    40381 ctagctattc ttctacaaca aggtaatata gttggtaatt ttggtagatt ggatactgca
    40441 acttcattgt tgccatctat taaatagaaa taattttaag gagagaaaaa atggattctt
    40501 atataagtat aataatacca gcttataatg aagaaagtag aataaaatat acattagaaa
    40561 gcatattgga cattaagcaa ataaatgaaa taatagttgt ggatgatggt tcaattgaca
    40621 atactgctaa ggttgtatct gagctagaaa atgaaaagat taaatttttt aagttagata
    40681 aaaatagagg taaaggatat gctttaaatt atggtatcaa attagcaatg aaaaatgcag
    40741 atattatagg ttttctggat ggagatttag gaagttctgc taaagaagtt gaaaaattaa
    40801 tagtacctat attaaatggt gaggcggatg ttacaatagc caagtttcct cctgcaaaga
    40861 gaaaaggagg tttgggattt gtaaaaggtt tagctaaaaa ttctgtgttt gagatgactg
    40921 gtgttgagtt agatgcaact ttatcaggtc aaagaatatt taaaagagaa gttttagaaa
    40981 agtttgatga aatacctttt ggatatggag tagaagttgg aatgaccatt gatatattaa
    41041 agtatggatt taaaattaaa gaagtattag taaatatgac tcataatgaa acaggaagaa
    41101 atttaaaagg ttttattcat agagggaaac agtattatca cataaaaaag gttttaggac
    41161 aaaaaaagaa agaatggagg taatatctta gtgaaagatt atatacttta taccatttta
    41221 ttattaactg gattatttgg aacctatgct gtaattccac tatttaaaaa tttattgata
    41281 aatggaaatg tacttagacc aaactataaa aaagatatga taccagtaag tatgggaatt
    41341 gtatttttgc ctatgattgt aatcaatgga ataatacttg ctttctttac tacagaattt
    41401 aaggatttag cgtatatatt tatgtttatg tttggtatga tatccatgtt ttttgcaggg
    41461 atactagatg atgtcattgg aaatagagat gtaagtggtt taaaggggca ttttaaaagt
    41521 ttatttaaag gaagtcttac aacaggaggt tttaaagctt tatttggtgg atttgtaggg
    41581 cttatagttt ctgttgctat atcaaaagac ataattgata taatagtaaa tacactaata
    41641 atagctctat caactaattt aatgaatctt ttggatttaa gaccaggaag ggcaataaaa
    41701 gcatatttat tcataatggt aattatattt ttaacattga caggatttgt tcaagttctt
    41761 ccattactta tagtaccaaa tgtacttgca tactttaatt atgatttaaa agcaagggct
    41821 atgatgggag atactggttc aaacgtcctt ggaatatcta ttggaatgct catttctttt
    41881 gggtatccat ttaacattag attaggatgg ttaatatttg tagttattat gcatatattc
    41941 actgagaaat actcattaac taagataata gaaaaaaata aactattaaa ttttatagat
    42001 aaattgggaa ggtagtatta tgataagcaa aagagtgggg attgttgaat caatagtaag
    42061 tcaaactgaa acactagatg atataagagt aaatataaat ggagaaatac aaagggcata
    42121 taattatccc aaaatatctg gaactataaa tataggtgac gaagtggttt taaatacaac
    42181 agcagtagaa ctgagcttag gtacaggtgg ataccatttt gtaataacta atttaaataa
    42241 tatagaatct actttaactg aaggtggaca tataatgaaa cttagatata cgcctcttca
    42301 aataaaagtg gattctgttg aggaacaaga aagtatttat catgataaat ttgcgaattt
    42361 taaaggatta gaaggtcttt ctgttgtagt agggactctt catagtatgt taactccatt
    42421 tgcagcttca tttaaaagaa ataatccaaa taaaaaatta gtgtatataa tgactgatgg
    42481 agcatctctt ccaatttatt taagtaaaaa tgtggatact ttaaaagaaa aaaaattaat
    42541 agatagtaca ataactatag gaaatgcgtt tggtggagat tatgaatgta taaatatata
    42601 tactgcatta attacagcaa aagaaatact aaaagcggat gcagtatttg tcagtatggg
    42661 acctggaatt gctgggacag gaacaaaata tggatttaca gggattgaac aaggctctat
    42721 tcttgatgct gtaaaaaaac ttgaaggaag agcaattgca attccaagaa ttagttttgc
    42781 tgacaaacga gaaagacatc aaggtatttc acatcatagt atgactgtat ttaaagaaat
    42841 tgtaaatgta aatgtagaca taccaataac tatatatgat gatgaaaaat tgaactttat
    42901 aaaagagcaa atcaatttaa atggtttaga caaaaagcat aatataattt atatagataa
    42961 taataaaacg aaagaggatt tagactattt taatctaaaa gtaaagagta tgggaagaaa
    43021 ttatgaacaa gatgaggcat ttttcaaagc tgcaagcaca gcagcatatt acttaatgga
    43081 ggtttaagat ggtattagaa gaaaaaacta ttagtagtga tagggtttat acaggtaaag
    43141 taattacttt aaaggttgat actgttgaaa ttccagggca aggatatcaa aaaagggagt
    43201 tagtagaagt tggtggagca gtaggaatag ttgcaatcac agatgataat aaagttgtgt
    43261 tagttaagca atttagaaaa cctatagaaa agccaatctt tgaaattcca gctggtaaac
    43321 tagaaaaaaa tgaaagtcca aaagaatgtg ctgaaagaga attaaaagaa gaaacagggt
    43381 atagtgcaaa aaatattaag ctaatacata aatttttcac ttcagcaggt ttttctaatg
    43441 agataatgtt tgtatattta gcaacaggtc ttactccagg agagaataat ttagatgcag
    43501 atgagttttt agatgtctat gaaattgagc ttgaagaagc atataacatg gtattaaaaa
    43561 atgacgttga agatgcaaaa acatctattg gattattatt agtaaaagat atgtttaaaa
    43621 attaatattt ataaaatgaa taaccctttg tcctaaagca tattatttta taaaggacaa
    43681 gggggaatta aattgagaag aacatataga aaaaatgatt ttagagaatt aaatagacaa
    43741 ataattatta taggattgtt gtttatgatg tctattgttg ttgggtctta cataaataaa
    43801 atattgccag gttctagtaa caatatatta aacaatataa atcctgctgt agagtattat
    43861 aatctaaata taagcataaa agatacagtg atacaaaatt taaaatcaga tgcaatcttt
    43921 atgggctcaa tagctctatt aagtctattt gtagtaacaa ttccagcagt gttggtagct
    43981 tttgtattaa aagggatgtc aattggttat acaataaata gttgtatatt ggcattaaaa
    44041 tttaaaagta taaaaatgat tttaataata ttatttaaaa atttgattat tattccatgt
    44101 gcaatcatat tagcattaat tagtttaagt tattttaaag aaatggttta tgaatttaaa
    44161 aagaaaaata gaaaaaatat gcaattttta attaagaggt atatactaaa tattataatt
    44221 ataatagcac tatcattggg gttgcaatta atattaaata ctgcaagtat tggtattatt
    44281 aagttcctag ctaaataaag gagtttataa tggatattat agagggatat atagattaca
    44341 taaaagataa aaaaaaatta tcagagaata cagtggcatc atactttatg gatataaaaa
    44401 aatatatgga atatataaat caaaaaagca ttaaactagt agatatagta gaaaatgata
    44461 ttataagtta cttaataaag ttggaaaaag ataatgtatc aatagctaca atagcgagga
    44521 tgatatcctc tataaaatct tttcatgatt atttattttt aaatcatata tgtacaaata
    44581 atcctgcaaa ggatataaaa aaacctaaaa taaaaaaaga aaatataaat atacttacag
    44641 aagaagaaat tgaaagacta ttaaattttc caaagttaac aacacctaaa ttgattaggg
    44701 acaaggctat ttttgaagta ttatatggta ctggtataaa agtatctgaa ttagtagaga
    44761 tgaatataga ggatattgac ctagatattg attatatata ttgtaattca tgttgtaaaa
    44821 atcaaagagt gataccactt tgtgatatta caaaacttta cttagaaaag tatctaaaag
    44881 aagcaagacc taaaatggct gtagaaggtg aaaaatcatt attcgtaagt tcattaggtc
    44941 aaaggtttac acgacaaggt ctttggaaag tcataaaaaa atattctaat ctagccaata
    45001 tagataaaaa tataaatcct acaatgctta gacattcatt tgctattcat ttgttaaatg
    45061 aaggtgctaa cattgctgtt gtaagtaaaa ttttaggaaa tgttaattta tctagtttgc
    45121 aagtatattt aaatcatata gataaaaacg tgagaagaga aataaaggag aaacatccta
    45181 gaaatgatgt tgatgtagaa ttacaaaaag cagaagctaa atagactata tagcaaattt
    45241 tataatttag aaggagcata tttatatgag cagagtaatt tggattgtaa ttgatagtgt
    45301 tgggatagga gcattgcctg atgctgaaaa atttggtgat agtaaggatg taagtaccct
    45361 tggaaatata tttaaggaat atccagatat tcagattcct aatatgagaa atttaggtat
    45421 aggaaacata gatggtatag atttttttga aagtataaaa gaaccaatag gttgttttgg
    45481 aaagtgtaag gaaatgtctc agggaaaaga tactactaca ggtcattggg aaatgactgg
    45541 tataatagtt gacaaaccat ttaagacatt tgaacatgga ttctctaagg agataataga
    45601 agagtttgag aaaaaaactg gaagaaaagt agtaggaaat aaaccagctt caggaactgt
    45661 aataatagat gagtatggag aacatcaaat aaaaactgga gatgtaatag tatatacatc
    45721 agctgatagt gtatttcaga ttgctgctaa tgaagaagta attcccctag aagaactcta
    45781 taatatgtgc aaaatcgcta gggaaataat gatgggggat aatgcagtag ctagagtaat
    45841 tgctagacca ttcataggta agaaaaaagg tgagtttgtg aggacttcaa atagaagaga
    45901 ttattcacta gacccatttg aaccaacagt tcttgataat ataaaagaat caggacttga
    45961 tgttttagca gttggaaaaa tagaagatat ttttaatgga aaaggaatta cagatgctat
    46021 ccacactaaa agcaatatgg atggagtgga tgaaacttta aattatatga aacaagataa
    46081 taaaggtcta atatattcaa atctcgttga ttttgattct aaatatggtc ataggagaga
    46141 cccagaagga tataagaaag ctcttgaaga gtttgatagt agacttcctg aaataatggc
    46201 taatatgaga gaagatgata ttttaataat caatgcagac catggaaatg acccaacata
    46261 taaaggtaca gaccatacaa gagaatatat acctgttatg atttatggca ataagattaa
    46321 aaaaggtttt aatttaggag taaaagatac ttttgctgat attggagcaa ctgttgcaga
    46381 tatactaaat gtaaagttgc ctaaacatgg gtcaagcttt aaagaagatt tattttaaac
    46441 tataaaatga taaaaactta gcttaatagg atggagagat tggaatgttt gaaaagatag
    46501 cacaaagtag taaatttata aattctaaaa gtgatataaa acctaagatt ggtttgatat
    46561 taggttctgg actaggtgat ttagcaaatg atatagaaga ccctgtcgca attaaatata
    46621 gtgaaattcc aaacttccct gtatcaacag tagcaggaca tgctggacaa cttgtaattg
    46681 gaaaacttga aggaaaagaa gttattgcta tgcaaggtag atttcattac tatgaaggat
    46741 attctcagaa agaagctact tttccagtaa gggttatgaa agaattagga gtcgagattc
    46801 ttatagtaac taacgctgct ggaggcgtaa ataaagaatt taaagcagga gatttgatgc
    46861 ttataagaga ccatataaac tttagtggaa gtaatccatt agtaggaaaa aatgatgaca
    46921 gatttggtgc tagatttcca gatatgtcag atgcatattc ttctaaatat gtagatgtag
    46981 ttaaaaactg cgctaaagaa tgcaatatag atgtcaaaga aggcgtttat atgtttttta
    47041 gtggtccaaa ctatgaaaca ccagcagaag tgagaatggc acaaattttg ggagctgatg
    47101 ctgtaggtat gtctactgtt ccagaagtca tagtagcttc tcactctaat ataggagtta
    47161 ttggtatatc ttgtataaca aatatggctg ctggcatctt aaatcaacca ctaagtcatg
    47221 aggaagtaat agaaactact caaaaagtta aatcagaatt tatgaattta gttaaaacaa
    47281 cggttaaaaa tttataagtt aaagcttatt atagattttt tgaggaagtt tataataaaa
    47341 tagttaatgt ttaatttgaa aagaattaat aaaaagctgt cttgatatag aaagttattt
    47401 ctaataaagg acagtttttt tataatacta caacatttga aagtgtttta aagtttaata
    47461 tttatttaaa ttattatagg ttagaatgga gatttcaatt atgagaatgt atgatattat
    47521 aaaaaaaaag agagataacc tagagcttag taaaaaagag ataaactact ttatagaaaa
    47581 ctattcaaag ggagatatac ctgactatca agcttctgca ctattaatgt cgatttattt
    47641 aaataagatg aataaacagg aaactgtaca tcttacagaa gcaatgatga actctggaga
    47701 catgataaac ctatctgaga tagatggaat aaaggtagat aagcatagta ctggtggtgt
    47761 tggagataag actaccatag ctcttatacc tttggttgct tcatgtggag caccagttgc
    47821 aaagatgtca ggtagaggtc ttggtcatac tggtggtact attgataaat tggagtctat
    47881 accaggtttt tcgacagaaa tggagataag taaatttatt gattctgtaa ataagtctaa
    47941 aatagcagtt tgtggtcaaa gtgcaaaggt agcaattgca gataagaaaa tatatgctct
    48001 tagagatgtt acagcaactg ttgataatat atcattgata tcatcaagtg taatgtctaa
    48061 gaagttagct tcaggagctg atgcaattgt gctagatgta aaaactggtg atggagcatt
    48121 tatgaagaca ttagaagagt cttttgagtt agctaaatct atggttgata taggtactgg
    48181 tatgaataga gatacaatag ggattgtaac agatatggat gaacctttag gttttgcagt
    48241 gggaaactct ttagaagtta tagaagcaat tgagacatta aaaggaaatg gacctaaaga
    48301 ccttgttgag ctatgcgaag tattaggagc atatatgttg gttttatcaa aggtagcaca
    48361 tgattttgaa gatggtgttg aaaaaataag agaatcaata aaatctggta ctgctataca
    48421 aaaactcaaa gagtttatag agaatcaagg tggtaataaa gatgtagtag atgattattc
    48481 tttattcaaa aaatcaaagt ataaatatcc agttaaatca actaaatcag gttatataag
    48541 caaaattaaa gctgaagatg ttggtgtatc ggctatgatt cttggagcag gtagagaaac
    48601 taaagatgat attttagatt tatcagcagg gataatttta gaaaagaaag taggagatta
    48661 tgtaaatgaa ggtgaagttt tagcttacat gtattataat gatgaacaaa agctttcatt
    48721 ggcaaaggga agatttattg attcctactc tattgtagat tcaaaaatag aaaaaaataa
    48781 attaatatat ggtattgtaa ctaaagaaga gattaaaaag ttttagaaaa ttttagaaaa
    48841 gtgattataa aaggcctaac atgtcaaaaa taatgttagg ttttttattt tttgatagac
    48901 tataaattat accaaaaata tatattttaa aacatttttt acaatataaa taagtttatt
    48961 ctacaagatg attgaaaatt aaagtatcta gttttataat agaaaatgga taaatataca
    49021 taaggagtag attatattat gaactttaaa gaaaatagat tgaaaatagc agtattaata
    49081 attgttattt tgattatctt agcaggtata tttgtgttta tacaaatagg tccttatgat
    49141 aaaaataaca aaaaagatgt aattatcgac gttccaagtg gagcatctgt tggaaaaata
    49201 tctgacatat tatatgaaaa taaattaata aagaatgaac tattatttaa acttttggta
    49261 aaggttagca ataaagctcc gtctataaaa tcaggaacat acttacttaa tcaatcgtat
    49321 tcaaacaatg atataataag tcttttagtt tcaggtaaaa tatatcagga tggtataaaa
    49381 gtgactattc cagagggagc tacatctaaa gaaattatag caatgttagt aagtaaaaat
    49441 ttaggagata aagctacttt tgaaaattta ataaaaaaac ctcaagaatt ttatgataaa
    49501 tttccatatt tgaaggaaga tggaataacc tctttagaag ggttcttgta tccagaaact
    49561 tattatttta attcaaagaa acaatcagaa gaagatattt taagcgaaat gttaaaagta
    49621 tttgacagta aatacacgga caagtttaaa aagaaacaaa aagaattaaa tatgactctt
    49681 caagaagtaa tggaaatggc atcaataatt gagaaagaag ctgttcttga caaagacaga
    49741 cctataatag caagtgtgtt ttataataga cttaaggtag gtatgcctct tcaatcagat
    49801 gctacaatac aatatatatt tgaagagaga aagaaaattg taacatatga tgatttaaaa
    49861 attgattcac catataatag ttataaaaat aagggattac ctcctacacc aatatcaaat
    49921 cctggtataa aatctattga agcagcatta tatccagaga aaacagacta tttatatttt
    49981 gtagctaaga ttgatggtgg aaataattat agtacaaact atcaagacca tttaaaatac
    50041 gttaaagaat ataaagaagc aagggataaa caatcaaaag atacaaaagc aacaaataaa
    50101 gaaaatacaa aaaaataaac catgattata aaaagtctaa cagggtaaga ataatgttgg
    50161 gcttttttat tgaaaattgt tattcttaga tttataataa agaaagtgta aatatatata
    50221 acaatatgaa tttaaaaaat aataaattaa tataaaactt gaatatttat tattttaggg
    50281 agtgttttta tgagtaatat agttaatgat ttggttgaag attatataag agtgacatta
    50341 aaagaaaaag aaggattttt aaaagattta gaaatttatg cagaggaaaa tagtgttcct
    50401 ataatacata aagaagtttc agatttatta aaagtcttgt taaaggttca aaaaccaaag
    50461 agaattttag aagtaggatg tgcaattggt tattcttcta ttttttttgc aactattata
    50521 ggaaaagatg cagatataat aactgttgag agaaatgaaa aaatgataga aaaagcaaaa
    50581 gaaaacataa aattagctgg atttgacaat aacataacta tactagaagg agatgcagaa
    50641 gaaaaactta gtcaagtcca aggtgaattt gaccttatat ttatagatgc agccaaaggt
    50701 caatataagc tattttttga tttagttata gataaattaa aagatggggg acttttagta
    50761 tctgataata ttttgtataa aggtatggtt gctcatgatg attttgttgt aagaagaaaa
    50821 aagactatag ttaaaagaat gagaaattat ttagattata tatgtaattg tgactattta
    50881 agcacatcat tggtaccaat aggtgatggt gtagcactaa gttataaaga aagtaaaaga
    50941 ggtgatgtag atggaattaa ataaagtaga acttttagct ccagctggtg atttggagag
    51001 attgaaaata gctataacat atggagcaga tgccgtttat ataggtggag aaatttttgg
    51061 aatgaggtct gcagcgaaga attttagtaa ggaagatatg gcagagggag tagcttttgc
    51121 acatgaaaga ggcaagaaag tattcgtaac agtaaatata atacctcata atgaagattt
    51181 tctacaatta gaagactatt tgttggaact agaagagata ggaatagatg cagttataat
    51241 agctgaccca ggagtgctta gtgtcattaa aaaagtaatt ccgaatatgg aaatacattt
    51301 aagtacacaa gcaaatacaa ccaattatct aagtgcaaac ttctggtacg agcatggaat
    51361 aaaaagagtt gtagtggcaa gagaattatc ttttgatgaa atatctgaga taagagcaaa
    51421 aacaccttta gatatggata tagaagcgtt tatgcatggt gctatgtgta tttcttattc
    51481 tggcagatgt ttaataagca actatatgac tggaagagat gcaaacaaag gttcttgtgc
    51541 tcaatcttgt agatggcaat atcatttggt ggaagaaaaa agacctggtg agtattttcc
    51601 aatatacgaa gatgaaaggg gtacattctt ctttaactca aaagatttat gtatgataga
    51661 gtatatacca gagttaatca aatctggtat aacaagttta aaaatagaag gtagaatgaa
    51721 gactgcatac tatgtagcta ctgttgtaag agcatacaga atggcaatag atgaatttta
    51781 cagagaccca gaaaactgga agttcaatcc aatgtggatg gaagaactaa aaaaaggtag
    51841 tcatagacat tttacatcag gtttttactt gaataaacca acaacagaag accaaaatta
    51901 tcaatcagca tcatatgtta gaaactatga ttttataggt atagttagag aaacagaaga
    51961 tgaagatggt cttattgttg ttgagcaaag aaataaaatg tgtgttggtg atgaaataga
    52021 agttatggga ccatataaag aaactatgtt tactaaaatt gaagaaatgt acaatgaaga
    52081 aggagaagct atagaatcag ctcctcatcc tagacaaata gtgaagttaa agctatcagt
    52141 aaaagttggt aaagattata tgcttagaaa agttatagaa gaaaaggttg aagaataata
    52201 aaaaattgat aaaaatagta ttagcccctt agaaattgtc aataatgaaa ttatctaagg
    52261 ggtgatttca tgtcaaaaaa gaagactcca tttttgaaaa aagtgggaaa gagaagctgg
    52321 tgtatattta ctataatttt aataatttat agtgttttaa tttataggct agttgatata
    52381 caagtattaa aaggtgataa atacaaacaa agtgttgaat cacaaagcgt tgagaaagtc
    52441 gagttaaata gtggaagagg aataatctat gatagaaaca acaagaagct tacagataca
    52501 agtaaatctc aggtattaat tgttgaaaaa gaaaaattaa ataataacta taaaattttg
    52561 gagcttatta agaaagctac taagatgaat gatttagata tatataaagc tgtacaagag
    52621 caattgacac gccctataat acagattcag actaaaaata tcgataagag tatgaaaaaa
    52681 gaacttgaga aaaatggaat aatggtagaa gaaaaaacta tgaggtacgc aaaagatggt
    52741 ttattatcac atacaatagg atatataaaa gaagatgata aatcaggtca atcaggaatt
    52801 gaaaagagta tggatagtgt acttagaaat tcaaatgaaa agtatataag tgcttttaaa
    52861 gctggagatg caggaaatga aaaatctcta aacatactaa agggaagtgt aaaaactgtt
    52921 gataataagg ataaagatag acatctaaaa actactattg attataacat tcaaaaaaaa
    52981 ttagaacaaa tactaaataa agaagaaaat cctacagcag caataatctc ggaagcatct
    53041 acaggtgaaa ttcttgcaat gtgctctaga cctaattttg accaaaatga catatcaaaa
    53101 agtttaaaag gaaaaaatgg agaatttgaa aatagagtta taaaagcgac atatccacca
    53161 gggtctgtat ttaagatggt agttttattt tctgcacttg aaaatggtgt tatagatgag
    53221 aactatactt acaactgtac aggtaagact aaagttggga atactaatga aatactgcga
    53281 tgtaataaaa gagatggtca tggtttccaa aacttaagac aagctttttc taattcatgc
    53341 aatcctgcat ttttagatat agctatgaaa cttggaaaag aaaagatact caaatctgct
    53401 gaaaaattac atttatttga aaaggttgat attggtcttg atgaagaaaa aattagagaa
    53461 gctccaaaaa acatatcaat aagaaattta gctataggtc aagaaaatat agaatttaca
    53521 ccacttcaaa taaatcaaat gactcaaata atagctaata atggaacatt caaaccacta
    53581 tacttatata aaagtcttgt ggacaataat atgaatacaa taaaaactta taagtcttca
    53641 aaaaaagaag aacttatttc tccttatgtg tgtacacaag ttaaagaata tatgaagtct
    53701 gtatctagga ttggtacagc taaagaccta aaagatattg aaggtggttg tggagttaaa
    53761 actggtacag ctcaaagtag tttaaataaa aaagctatag accatggatg gataacagga
    53821 ttttatcctg aagaaagacc taagtatgta ataactgtgt tagtagaagg aactcaaaaa
    53881 ggaaataaat ctgcaacacc tatatttaag gaaatatgtg aaagtataaa ataaattatg
    53941 tactataaaa tttaaggata tatcgtaact ttgattttag atagaaaatt ttgtctaatg
    54001 atgtacgata tatcctttta aaatatagta ttaactttct tgaacaagct ctttttctag
    54061 ttttttaaga gctttttttt cgattctaga tacatatgac cttgatatat cgagtttttg
    54121 tgcaatttct ctttgtgtct tatagccata aggagttaac ccatatctta actggacaat
    54181 ttctctttct ctaggagtaa gaattttgtt tagttgttcg taaagttttc caacttgaac
    54241 ttttagttca acttcatcaa gaacatagtt agcctctgta ccaagtatat ctaaaagact
    54301 tatttcatta cacactactc tttatatgtt attggtatta ctggtcttca tgtaatttca
    54361 aatggaccat taattcaaaa gaatctagtt tttgttcttt agacttataa taaactgctt
    54421 tatcaattac agattttagg agtttatttt ttccaaggga atctgaatca tggtaaagtg
    54481 ataacacagt tttaatatct tctattattt tagaattgtc ttttttaaca gtacttaatc
    54541 tattttttac tgtcttaatt gaatctttaa tttcttcagt tcttgaactt atattgttgg
    54601 acctttcaat aaatgtatct tcatcatata ttcctcgttc tagtaaatca tataacttat
    54661 ttttttgctt gcctaattct tttaattcag tttctaagcc ctttaagact cgtttttgaa
    54721 attctatatt actatcttta ttatttttat ctaagtctat atcagatgct tttaattgat
    54781 atttttttac agtgtcttct aaagatttta aaatggcagc ttcaataaat tcaaatcgag
    54841 aacttttatt gcaaccagga tgataacaaa ttatatagtc gtggtctgca tatggtctat
    54901 atactaatgg tctaccacaa tttttgcaaa tcactattcc tgcaagtgga ttttttattt
    54961 gattaccata gctgacatga ccattttttt tgagtatatt ttgagctttt ttccatgtta
    55021 tttcacttat taaaggttca tgctttcctt ttgcctcaat ccattcatct ttaggtctta
    55081 gtttaactgt ttttatttta tttggatttt tagatttttt gtagtccttt ttttgccact
    55141 gaatgtagcc acaatatacc ttatttttta ttatatttgt aattgcagaa ttgtaccaat
    55201 tagcacctgt agcagtttta atgcctaagt tatttaggta ttttgatatt ttactacaac
    55261 ccatatcttc attaatatat aagtcaaaga tagtcctaac tacatcagca tccttatttg
    55321 gtacaagtat tctttctttt ctaccagttg ttacagcatc atatccaaat ggagcagagg
    55381 ttcctatgaa attcccttct tcaactgatt ttattctacc tctttgcatc cttcttgata
    55441 taagttttaa ttcttttctt gccataaatg cttcaaattc tgaatactcc tcatcaaatt
    55501 catctgttag gtcgtatgtt tttctaggtg tgataatttt ggtcttactt tctttgaatg
    55561 tttctaatat gataccttgg tctttcatgt ctccacgacc aagtctgtct aagtccatta
    55621 ctaagactgc atcatattta ttttcttcaa cttcttttag aagttcaagc attttgggtc
    55681 tatgtattat actttcacca gaaactaatt cttcttttat ctcaattaca tctaagtttt
    55741 gttcttttgc tagttttagt agggttgatt tatgtctact taaagtttca aattcgcctt
    55801 gtttttctgc ctcttcatca gcacgggatt ttcttaagta tatggcaaca ctcataataa
    55861 gtaatcacac tccttatgca ctattatata gtaaatcaat agagtttaaa atatagaaaa
    55921 taagcatgtc aaaagttaat ttaactttca acatacttat tttctataat attaatgcct
    55981 tataatcctt taatatcatt tagattagtt tttgcatatt cattatccgg gttaagttca
    56041 agcgccttat tgtaagattc tctagcttta ttaaattctg atttactcat aaaaataaca
    56101 cctcttaaat tgtaagcatc actagcgtct attttataag cttcattatt tttatctaga
    56161 tattctaagt atttatcaat tgactttaaa gcctcatcat atcgttgtaa ctctatataa
    56221 atatatgatt gtgtataata tgcaagtgga tttttatcat caatttctat agcttttttg
    56281 atatcaatag cagctttatt ataatcctta tcttcatctt tttctgtttc tgacctagcg
    56341 attttgacat aattagagct aagagctctt ttaaagtctt tatgccataa taatttatat
    56401 tcattatctt cgattataaa atatctatca aaatttgcag tatcttcttt attttcagtg
    56461 atatacttta tagtatcagt ttcttttatt ttaacaagat ttgtgtactc tttattagaa
    56521 tatttgtatt tctctacttt attttcttca ccaagtttat aatcttttag ggtttgaagt
    56581 ttaaataaag tatcttgata ttcttcaaat ttttctagac tgacgctttc cttactgtct
    56641 ttacttaata aattatatgc tacttcgtag tctttgattt ttatactatc aaggtacttt
    56701 ttagctactt ctgtagcact ttcttttgga gcacatccaa ccattgatat cataattaaa
    56761 aatgatacta atattgctgt tattttttta ctgattatca taatataatc ccccttatat
    56821 tgtctctcat taattttatt ttatcaccat attctaccaa agtcattaat ttaagagtga
    56881 tatttttcat taatattata ttaagtaata ataacctttt aaatttatgg taacattttc
    56941 ctgaaaagta ttatataatt taggtgaaaa tatttaagag aagtagatat tatgaaaatt
    57001 aaaaaattat taacaatagg gttatcttta tctatattta ttgctagttg ccctatatct
    57061 gcaaatgctc ttgataaaat tgaaccaatt aaaggtgcag ataaatacga aactgctggt
    57121 ataattgcag acaaataaaa ctatactaca gctatattaa ttaatgcaga cagtacaatg
    57181 tctgatggat taagtgcaag tggacttgca ggagctataa acgctccaat tcttttgact
    57241 aagaaaaata acataccaaa tgctacactt aaaagattag aaaaggcaaa aaaagtatat
    57301 ataattggag gagaaaactc tattgataaa tatactgaaa ctgttctaaa aggcaaagga
    57361 atagagatta aaagacttca aggtagtgat agaattaaga caagctataa tgtcgcaaaa
    57421 gaaataaact caattaacaa agtaaataaa gtcatattga ctaatgcttt taaaggagag
    57481 cctgatgcaa tgagtgctgc acctgtagca gttagagata aagcagctat agtattaact
    57541 gatggaaaaa gtgtccattt aatacaactg gtgtagaaag ttatgtaata ggtggtactt
    57601 catcaatgaa tgacaaaata gttaaggata ctaattcaac tagattaggt gggacagata
    57661 gatatgatac taacaaaaag ataataaata aattttatag tggagtaaaa gaattttata
    57721 tagcaagtgg tactgattta gtgtatgctc ttgttggttc taccattgct aaaaataatg
    57781 ctattgtgtt agttggtaat gatagtaata aaagtgtatt gaaaagtaca actaaattaa
    57841 ctgctatagg aaatttgagt gatagtatat tacagcagtg tttaaatgta acaaaaaata
    57901 taggcgattc taatactgga agagaatata cagtagaaga tgctgctaat gtagtgaaaa
    57961 aactattagg tgtgaagaaa ttttattacg aacctaatta ttcagaagat gaagatttaa
    58021 cttacaatct atagagtgga gttcatgtac aaaagattat cctcccaacg attcgaaggg
    58081 aggtgagttc atggataact ttttgtttaa tgttttagct agtttaacag ctagtgtggt
    58141 agtttactta atcagtaaac tattcaaaaa agcaaaaagc cactctcgca caaagagtga
    58201 cttacgagtt gaatttaaat ttatatttaa atccaaaaaa taaactctgt ttatgatgaa
    58261 ctccactcta acgcaaaata gattgtagtt cttcttgctt ttattatacc acaaaacatt
    58321 ataaataaaa ctgttgttta taaaaaaatg caaagtaaaa ttttttataa acaatgataa
    58381 aaattttatt atagagctat taacttatga aatatctgta aatgagcaga tattttataa
    58441 gttaatattt attgtttaca taaaatattt ggtaaaaata agtaagtttt atatgttata
    58501 atagttgtag caagaataat aatctaaagt ggcaagcatg tcagctggtg ttatatcagt
    58561 ttatatttat gataaaataa aaatctccca aacgccaata agaatgattt aaaaaaataa
    58621 tattttcact taaaaataat cactctttat aggagtaaat tattttcttg attttattat
    58681 actacaaatt ggtacagata tttaaaaata atatattcat aatattataa atagttttgc
    58741 agtgagcgat atttttgata aaatagggct taacagttga aacataaggc attgagggta
    58801 tatgataaat attatcattt gcactactcg tggttcactg caaatttgag agaattgtat
    58861 agatgtaagt gttggaaata ctcaatttat tttggggttt tatattaact aagtggtatg
    58921 taaaggcaat aaaacctgct attcttggta gaaattcatt tggttttata ttaactaagt
    58981 ggtatgtaaa gtttgacgtg ttaagtgata tagatagaag aatatgtgag ttttatatta
    59041 actaagtggt atgtaaagtt tgtttctctg taacatgatt atcattcata attaaagttt
    59101 tatattaact aagtggtatg taaagagagg ataaattgtt tacatagtac cagttgggtc
    59161 ttgttttata ttaactaagt ggtatgtaaa gttgcacttg aatagttctg aagaacttaa
    59221 gaactatggt tttatattaa ctaagtggta tgtaaagagc tttacaatat caaagaaaaa
    59281 ttgaaacatc tatgttttat attaactaag tggtatgtaa agggaaaatt atgggaaaag
    59341 tttacagata tcatgagagt tttatattaa ctaagtggta tgtaaagtaa aaataaacct
    59401 cctaaacaaa tatttcacgc atagttttat attaactaag tggtatgtaa agcttgtaat
    59461 cgctgaataa agatttctag cttcgttatt gttttatatt aactaagtgg tatgtaaagg
    59521 actctgccat ccctgtaacg aacagcctta cagcaagttt tatattaact aagtggtatg
    59581 taaagactta tctgtaaccc ttatatgttc aaattcatag ccggttttat attaactaag
    59641 tggtatgtaa agtatttcta gcgacttagt cggttgctcc atttagcgtt ttatattaac
    59701 taagtggtat gtaaagtagg attgacacgt tacgaccgtg caacgttgga ctggttttat
    59761 attaactaag tggtatgtaa aggcaataat attatcaatt ttaatatttt gtttctcatg
    59821 ttttatatta actaagtggt atgtaaaggg ttctggcaag tcacttcatg ttgctagaga
    59881 tatttgtttt atattaacta agtggtatgt aaaggttttt tcttcgtaac tttgagcctt
    59941 acatccacaa agttttatat taactaagtg gtatgtaaag aacaaaaaag atacatctgt
    60001 aactaatttt tatactgttt tatattaatt aagtggtatg taaagacaga tataatgtca
    60061 aaataaggtt aggactttta aaagcatagc catatcagta aaaatttaat tatcatttaa
    60121 aaaataaatt tttatttaaa gaatacacat aaatatttcc agactcaact ctcttaaact
    60181 attttcatat cttttagtag atacctttgt tgttttttaa tctttagcaa cttgttcttg
    60241 agtgaacctc ttattttttc taagttattt caagcttttc aaaaaattct ctatttatat
    60301 tcatcacaca tataatacaa ttaattcagt tttaattgcc aatatttagt ttttctgtat
    60361 ctgataaacc aagaatataa tcagtatata aaccaaaaat tttagcaaat attattaacc
    60421 catcttctct tgttggtctt tcaccagact ctattctatt cataacactt gtatttatat
    60481 ttgttttttc aagcaattct ttttgagaac tattcatatt ttccctaata tatttaatcc
    60541 tttgatttac atccatacat aattatctcg aaaagtttct gctttggaaa tattgttatt
    60601 gaaatataga aattaatgtg aatatatgaa aaagatacac tatgatttta taaaaaagaa
    60661 gacatacata aaatttatac ttacaaagtg ttgcaaaaga gttaggtttt aaaaatgcat
    60721 caacttattt taagtacagg aaagggtaat attcaattag agttgatata ttacctataa
    60781 actatctaag atacttgatt atgatataga aaatttaatt aagaggatga taaggatgaa
    60841 taatttacaa gtaatataaa gaaataataa gagaatttta aatacatagc aactagcaga
    60901 tatatatgaa aatgatgtaa acaatatata aactagcttc aatagaaata aagagaatgt
    60961 aaattatgtt ttattacaat tcgagtattt gaaagaattt aagaactaac ctactaatag
    61021 tcagttgatt tcaaaacatt ctagtcaatt atacatttgg accgaaagat gtgcaaatag
    61081 acactgcaaa atattagata ttgataaaac ttgagaacaa tttgacaatt tagagaaaat
    61141 atatttcaag attaagcgag agaaactaag ctgtatagaa gatgtattaa tagaaaattt
    61201 aatatttaag gatacaaatt aatcaagcaa taatatggca ttagaggtaa aaatagaagt
    61261 taaaataata aaagatgttg ttatattaaa tataacacat tggaaaaaag aaacaagtct
    61321 attaacagtt aaaattgcta gaggtcaagg tgatttaagt tatgtaaaat attttactaa
    61381 tgagagctaa gagcttctta acaagagttt tggtgtgtct attgaaataa tgttaacaat
    61441 taataaaaga cgaatggcag aagaaggcgt atgtaagttt aaaagagata agttaaacaa
    61501 actagatact atataagagg ataagaaact tatagaagaa tatgttactt ttgtaaagga
    61561 tttagcttta atatatagaa tataaagtga ttttaagtaa aaattgtaac aattaaataa
    61621 gtataagaca agtttatgag ttcatatttt ataacaaggg gtgatgttat gaaaatacta
    61681 caacaattta aaccatacaa atatgataaa gaaaaaaata tagaatatga tgaaaaaatt
    61741 atagctaatc aaaacacaga agtttatata gtatatccac gtatatctga tgaagaaaat
    61801 aggagaagat gggaagagtt caatgaagta gctaaagaag tagctattaa tatagctatg
    61861 aagaaagttg agacagtaga aagttaagag aatagagaag ttgctaatac ttagcacttt
    61921 ctcatagaag aaaattggac aactattttt aaataattag gaataaaaaa gttaaatcat
    61981 atttgaaaaa aggcgataaa attgttgagt attgttatta gtaataagaa tgtattaact
    62041 atgtattaaa agaaattata agtttttagt aaatatagta tttaaggata ttaaaactgg
    62101 taaaaaatat catttagact attaaataaa aaagtgctgg tcaaagtaag caacacaata
    62161 aataaaaaaa cttatagaaa ttataagata aaaagatgag atttgaaatg gttgaagtta
    62221 atataaaaat taaaggtgaa gtaagtgaaa taattgactc aattagaggt atatttaata
    62281 gctttgatga agagttgata ttagatataa aatcagagta agaatataaa ggtagatacg
    62341 tagaaagtta taagtaattc aagacttaaa ttaatttcta gtttttttaa tgcaaaaatt
    62401 taataaattt caaaatataa taattctgac atctaaaaag agctattaaa aatgaataat
    62461 attgactatt aagatatgaa tagtgtacat atattaaatt aagatatcca gtaggttaat
    62521 tttatataat gatggggctc aaattgaaga ggcgatataa aaatgtatta atatatataa
    62581 atataagaac tataataaat attaactgta aaattaaatt tatagagtta tatttaacat
    62641 ttaatgaact gaaaaataag ttagcaaata atgaaaaaac aacagtaata aatgagaata
    62701 acaaagcatt ttcaggatta gtggattttt ctaattgagc tttaatccta gtttgttcaa
    62761 tttcgatatt tctaatatta ttagtattat caatttattt gtaataatta tcagtttttg
    62821 cgaaatattt ttgataattt atagaacttt atatattttc cttgaagtat ttttcgccct
    62881 tattgtttgg tttccaattt taaaactcat aaactcccaa taaattcatg tataatatac
    62941 cttaatttat aatatattta agagtttatt tcagtaattt ttcgaacgat tttgatatat
    63001 ttcatttata gttttcaaaa acttatacaa aaaagagtgt ttcatttttc taaacactct
    63061 ttttataaga atttgaataa taatttttta aaaattgata atatggttat ttctttttca
    63121 agtttatagt ttcctcattt ccattccaag atataattag cttgtaacta gattctctat
    63181 ttgaataaag acctggtctt tgtattttta ttgctttttc ttgacctgct tctaaaattt
    63241 cattttttac aactacaact gcatcttcac catctataaa ttgataggaa taattaaatt
    63301 tttgttcaac tacatcttta ctatttttat attttatttc taattttgag tgtccttcag
    63361 tagttacaaa tttcgctttc caattttctg attctccaat aaagacattt ttatcatttt
    63421 ttatattaag tatagctatc acagagatta ttaaaactat aagaatacct ataaaaaatt
    63481 ttttcctcat atcaatccct cctttgaata attataacat gagaatagtt attcaatact
    63541 aattttaaaa atattgtgga tttatattct attacaatag aatgtctgtt ataacaaata
    63601 aaaagtaggg attaatatga attataggtt aaaaaaatct gtaacaacta ttttatcttt
    63661 actcataatg acaatactat taccaacaaa tgcaagtgct agtaaggtag aagattcatc
    63721 tatgaaagta atgtattcag agaaacaagt aacagacatg gacaaattat acgatatggc
    63781 taaaaatgga attactgatg ttaaaagttc caatgaaaaa ggtataatca aaaatgcaag
    63841 aacaggagag tccatatacg ttgattctat atcaacaact caattattag aagttaaaca
    63901 atctaaaaat ttaacatcaa agatatattc taagacagtt ttttgatact aatacaataa
    63961 agcctcttag aaaagcaagt atatcagaag atggatggga taaaactggt ggtgtaaaag
    64021 catctggtac agttacatat acaatatcaa aaggagatgg agcatttcaa tatatttccg
    64081 ttagtaaagt ttctggaaac tggtctattg cagacggcca gattcgtgta acaaatagaa
    64141 gggtgcatat aaatcaaact ggatttattt ctaatgggct aggaattaag cagcaacaaa
    64201 agaaagagcc aacatcaaat tctttctcat ataatgcacc ttctagttgg aaaccagtag
    64261 gtagagattc agttcaatac aattgtgggt ttgaatcaat tgcaacatta gtaagaggag
    64321 gaagttcttg gtcattcaat ttcattgttt aaccttaaaa tattttaagt gaattttatt
    64381 aaaattaaag atatacatat actttaaaat tagaaaatgt aaattaattt gtgtttttaa
    64441 agataattcc taagttatag caacaattgc ttatttacta ttaatatttc ttaatatatg
    64501 aattttattt taacaaatta taaagaatgt atattgggat gtttttaaat atttttggaa
    64561 attatatata ttataacaat tatagcaaat ttttagggta taatttttaa aattatattc
    64621 tactatcaaa agatatgaat aaatgattgt atatattata tcaattttta tatttcatag
    64681 tccatttttt catcacattt tcgcttgtca agaataatat ctttaagagt gaagcgtttg
    64741 atgtaaatct ggactttgtt tttgagacat ttttgaaata tttattaaat ctttcgatta
    64801 tacttgtaat atatattata gatattactt attttagtaa aactaaagga tgatgctaca
    64861 acattccagt tatttcccaa aattttaatt tctgaagtat actgtttaca ttatttttaa
    64921 tctattttat ctaaagtcga taaggcttct tattcattaa ctgacctata tacagattta
    64981 aaattactta ttaattcttt tgagtccttg tatgaaacat atttaaagta tttcttatct
    65041 aatgtattaa acatttttgt attacagaat gaggataact tgtagctatt gtctctttga
    65101 aataagtcat ctgtgtttac tcctaaaact acttatatct gtagatttta taagttctcc
    65161 atcttatata atttctttga ttaattgttt tcttaaatta ttcataaaaa aatctccgtt
    65221 acgatatttg attatattta aatcattgct ataaagaaga cttttattaa ctttgaaaaa
    65281 caaattattt taattgctgg tgattagttg ctaccttctt ttgatattaa ttctattaga
    65341 ttttatatag ttatatatct ctttctaact aagtaatata atatta
//
LOCUS       DAMJVG010000013        59463 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.013, whole genome shotgun sequence.
ACCESSION   DAMJVG010000013 DAMJVG010000000
VERSION     DAMJVG010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 59463)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59463)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59463
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.013"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            <1..606
                     /locus_tag="PC512_000944"
     CDS             <1..606
                     /locus_tag="PC512_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDF2440713.1"
                     /translation="ISGYLTKKLQDLNVDTIRTDILTSPTVTDVIVWNIEQSGTDTFS
                     ATYEVDQQIKEGEQTTTVKATYTVKVHVDADRDMVIIQNPTLAPAIEKSDYEPKTPEA
                     DASVDADTVNDATAFLETFFKLYPTATAKELAYYVFGNVLEPIGRDYLYSELVNPVLT
                     KDGDNMKVKVAVKFLDNQTKATQVLQYELILHKDSNWKIIM"
     gene            819..1676
                     /locus_tag="PC512_000945"
     CDS             819..1676
                     /locus_tag="PC512_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002585362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2440714.1"
                     /translation="MYKEVGISSNNVPITLSIWYTERSSPTIVFLPGTMSHPLMYENF
                     LCGLSERGFNIIGIHYLSHGKSPKIKKNYTMEDLLHNVYDATTYGIENFGENIAVMGS
                     SQGGILAAMAAGRDTRLKAVFPHNIMLTTLKETMSLTKYPTWSHRFMGLIQWGFRVGG
                     KLLPNYKVPGDAYLDYDRVFYSEQAKQDCLNDPMLLPYYPLRFVTSLFNADLSCLENG
                     AIQCPVILITAKGDPLFSFDYTNKVFDLIHVPQKELLALELNRHMIFNEDTDTTINAL
                     EATLHKYLG"
     gene            1754..2335
                     /locus_tag="PC512_000946"
     CDS             1754..2335
                     /locus_tag="PC512_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2440715.1"
                     /translation="MPRFTEQEKEIINSKLLIEGEKLFALHGLKKVTVDDLVAAVNIS
                     KGSFYAFYPSKEHLYVEINFRLQKELFTSIETTIKKKKYKNHRDLAKDVIMLSLTGVI
                     TSPILSQIDLSLMDYLQRKISSDIFENHMYSDIRILEILEDLGVVFLVPHTVIIKSLY
                     SVLSCLEQFKEDEELNMIQNLLVNGIIQQVVAE"
     gene            2439..3284
                     /locus_tag="PC512_000947"
     CDS             2439..3284
                     /locus_tag="PC512_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2440716.1"
                     /translation="MIDVKKLYFSYTDKPFVENVSFHVGRGEIFGFLGPSGAGKSTIQ
                     KVLTGLNTRYKGSVKVAGTEIREHTNQFYENIGVDFEFSTCYEKFTARQNLAYFASLY
                     EKQPRSIDELLHMVGLENDGDKKVADFSKGMRSRLNFIKALVHDPDILFLDEPTSGLD
                     PTNSRLMKDIILAEKKRGKTIIITTHNMFDATELCDQVAFIVAGKVSALDSPHNLIMS
                     RGAAKIQYTYYDKGEKTGECLLDRTTEDKLLKSLISENRLLSIHSSEPTLNDIFVDIT
                     GRTLQ"
     gene            3281..3964
                     /locus_tag="PC512_000948"
     CDS             3281..3964
                     /locus_tag="PC512_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016295773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2440717.1"
                     /translation="MRLGRLICGDIHFQWKYGFYFIYFILTVLYVCGIAALPEHWKTD
                     IASIMIYSDPAAMGLFFMGAIVLLEKSQKVLNAMVVSPVKISEYILSKTVALIAISTV
                     IALILGVVSGSNHLLGIAVGTALTSAIFTMLGIIAATKISNLNQFLIVIMPIEIICFV
                     PPIVGLFVKLPYLFRFFPFTACMNLITGKSVLLSFDMVLVIATLIILYIVARHTVEHM
                     WKSLGGVKL"
     gene            3961..4659
                     /locus_tag="PC512_000949"
     CDS             3961..4659
                     /locus_tag="PC512_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002583502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2440718.1"
                     /translation="MKKILSSTIQIFKQIKSDPMMFAACFSPFIMGTLIKFGIPFLER
                     ITKFSLQAYYPIFDLLLSIMAPVLLCFAFAMITLEEIDDKVSRYFSITPLGKSGYLFT
                     RLGVPSIISAVIAFIVLLLFSLEKLSIGMTICLALLGSVQAIIVSLMIITLSSNKLEG
                     MAVTKLAALTLLGIPAPFFIDSYYQFAVGFLPSFWVAKAMQNEAVLYFSIGLVVALVW
                     YYFLTKRLFRKLAG"
     gene            4671..5582
                     /locus_tag="PC512_000950"
     CDS             4671..5582
                     /locus_tag="PC512_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HDF2440719.1"
                     /translation="MEKGRLLQNKNMNKAIQVSKITLIINLSLSLLKFAAGYIGKSSA
                     MLSDAVHSASDVVSTIVVMVGIKISEKQPDREHPYGHERMECVASIILSVALAITGAG
                     IGYSGIKKIFSGQYNTLSVPSGIALTAAVLSIVIKEWMYWFTRSAAKHTNSDALMADA
                     WHHRSDALSSVGSLIGILGARLGYAILDPIASVVICGCILKAALNIFKESINKMVDHS
                     CDNATETRIREVVLQQQGVDGIDELKTRMFGAKMYVDIEILADGNLALYDAHRIAEGV
                     HQTIENNFPQCKHCMVHVNTNELLYSA"
     gene            5634..5774
                     /locus_tag="PC512_000951"
     CDS             5634..5774
                     /locus_tag="PC512_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440720.1"
                     /translation="MEQYWWIIIVVVLIVVGLLKIVIMKKYNQRRNSNNRSKDSEDDK
                     MY"
     gene            6065..6691
                     /locus_tag="PC512_000952"
     CDS             6065..6691
                     /locus_tag="PC512_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2440721.1"
                     /translation="MSDTKENILKIALHLFAVNGYEAVSVSMIAEALGMTKGALYKHY
                     KNKQDIFDCIVERMYQIDNKRAKDYQVPESTIEVTPNAYRNTTIGSLITFTLAQYDFW
                     VTDEFASNFRKMLILEQYRNLKMNMLYQKCLVNGPISYIEDIFNEMIEKGVLQECDTK
                     QLAIEYYAPLFLLISVADAVENCWDLKTQLTTHVKQFVKKYIINEKVK"
     gene            6813..7529
                     /locus_tag="PC512_000953"
     CDS             6813..7529
                     /locus_tag="PC512_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDF2440722.1"
                     /translation="MEYIRSKKYFTPDLQTKIMGPNPIKLQEELLQNHKIPSGSYVCD
                     LGSGQGLTSVFLAKEYGFVVFAVDLWSEPKENEEFFKKMGLSSAQIKSVKADANELKF
                     EKEFFDAVVSTDSYNYFGRDPIYLDEKLLPFVKKGGFVYITVPGMKKDCHEKLPEELL
                     LSWTPEELDYIHDITYWSNIISHCKKADLISIYEMESNSEVWSDWIKQNNEYAINDRK
                     AIEAGGGDYLNFIAIILQKK"
     gene            7679..8275
                     /locus_tag="PC512_000954"
     CDS             7679..8275
                     /locus_tag="PC512_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015541496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HDF2440723.1"
                     /translation="MKILWIIIIMADNLLPLLLARFYPNYKHKEMALSVLGSRQSPVK
                     WIYNVWCIISGVVFCIAPYALYQENDSGWAIAIWMLLAIYGIGCEIISGVCPLNENRQ
                     DEDIITKIHGGTSAIGFMALLVVPLLFAILQFQTTKVVLGAISLVCFTIAFIFFCFFI
                     MGEKEKFANTVLRYGGLWQRLVLISCYIPLFVWSVSNQ"
     gene            8362..8553
                     /locus_tag="PC512_000955"
     CDS             8362..8553
                     /locus_tag="PC512_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003064779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4177 domain-containing protein"
                     /protein_id="HDF2440724.1"
                     /translation="MKKYEYVEINYNAKGVVFLCTDKHKEIIDSYAKTGYHYAGFVPT
                     EIDAKGCMRKIDLIFEKED"
     gene            8577..8807
                     /locus_tag="PC512_000956"
     CDS             8577..8807
                     /locus_tag="PC512_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440725.1"
                     /translation="MIGLKRRDMNYIMKVGAKAQGVSVSEFRAMLQDTIDKTMESTDP
                     DVQANFKRYFGNKRPTPEEYIYTITKKTKVKV"
     gene            9074..9493
                     /locus_tag="PC512_000957"
     CDS             9074..9493
                     /locus_tag="PC512_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009261829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF2440726.1"
                     /translation="MKPSDFQKTIQCQFECKLKKVVKGIIWNYRKELKRRKNKEISFS
                     ELPDITVESLATWDDYETNYTIFNVCGIDIKVLDDELAEALKQLPEKKRNNVLMYYFL
                     EMSDTEIADIMNYTRGAVFKHRHRALETMKEILKEKK"
     gene            9496..9750
                     /locus_tag="PC512_000958"
     CDS             9496..9750
                     /locus_tag="PC512_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2440727.1"
                     /translation="MKKKYKHPSYYLISSAMDGDETAIEKLLAFYDPYISKCCLRPLY
                     DEYGNVYIVVDMELKGRIREALIKMILDFEIDIDIETEEE"
     gene            10125..10328
                     /locus_tag="PC512_000959"
     CDS             10125..10328
                     /locus_tag="PC512_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HDF2440728.1"
                     /translation="MNNTDVPIWEKYTLSIEEASRYFRIGEKKLRKLAEENLDSGWVI
                     VNGNRIQIKRKQFEKIIDTLDEI"
     gene            10406..11596
                     /locus_tag="PC512_000960"
     CDS             10406..11596
                     /locus_tag="PC512_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006354938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDF2440729.1"
                     /translation="MSKMKRQDSKGRNLRLGESQRKDGRYVYKYTDIFGKPQFVYAWK
                     LVPTDKTPTGKRDDKSLREKEKQIKKDLDDGIDTIGGKMTVCQLYAKKNNQKKNIKRN
                     TEIGRQYLMNALENDPLGMRAIDTVKQSDAKEWAIRMNDKGYSYKTIDNYKRSLKASF
                     YMAIQDDCIRKNPFHFKLSDVLEDDTEPKVILTPEQEEKLLSFMETDNVYSKYRDEVI
                     LLLETGLRISELCGLTTHIDMLNRVINIDHQLLRDTEVGYYISTPKTKNGKRELPLTE
                     RAYQALERILKNRGKAQPLVVDGYSNFLFLNREGLPKVAGNYESMVRGLIKKYNKTHE
                     DKLPNITPHSFRHTYCTNMANKGMNPNTLQYIMGHANITMTLGYYAHGTFQSAKAELE
                     RLAS"
     gene            complement(11853..12653)
                     /locus_tag="PC512_000961"
     CDS             complement(11853..12653)
                     /locus_tag="PC512_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2440730.1"
                     /translation="MRLNKRSEGYINYVKGVKREKRNVLFYQLLILIGFIVIWELLAD
                     LNVINTFLFSKPSDIYNLFIQYAFSGQLFKHIGISVYETVLGLVIGTVLGILVAIALW
                     WSEKLSKILDPFLVVLNALPKTALAPIIIVWVGAGIEGIVVTAVTISVVVTILSAYNY
                     FMNIDEEKIKMLKSFGATKSQILFKLILPANTGNLINLTKINIGMAWVGVIVGEFLVS
                     RYGIGYLIVYGSQVFKLDLVMMGVFVLAICAWAMYAVVNIIEKIYNSR"
     gene            complement(12848..14446)
                     /locus_tag="PC512_000962"
     CDS             complement(12848..14446)
                     /locus_tag="PC512_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDF2440731.1"
                     /translation="MKAAIYSRKSRFTGKGDSIENQIQLCIDYAKSIGVKDFLIYEDE
                     GFSGSNIDRPQFKKMMQDAKDKKFSYLVCYRLDRISRNVSDFSTLIEKLNELSISFIS
                     IKEQFDTSTPMGRAMMFISSVFAQLERETIAERIKDNMYELARSGRWLGGNTPHGFNS
                     EKITFLDENLKERSMYKLQVNDEQMEIVKLIYNKYLELRSLSKLYKYVYNNGIRGPRG
                     GKFDPSSLSRILRNPAYVKANDEILDYLKNSGMDVVGTPDRKCGILTYAKNTSNSIAA
                     IAKHHGVIEPEIWLEVQNQLDKNRDKTPRISTGKTALLSGLIKCGKCGSNMRITYKGK
                     KTDKDLKYYYICGTKKTLGSDSCNCKNLNGPLVESLVIDKIKNCKEESIISAFNSNNI
                     KTDNVFNIFKSETNLLKNQILDKERLIKNLVIELAKNTGSTASDYIVSQIESLNNEIS
                     ILKDKINILESSNINISSDSINIDIIVSNLKRFNDEVDNASLDDKRLLLSTIINSIVW
                     DSSLGNLNIVYMGAEVDNSVSLSN"
     gene            14774..14950
                     /locus_tag="PC512_000963"
     CDS             14774..14950
                     /locus_tag="PC512_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440732.1"
                     /translation="MEINVIEIFPKDKAKLNKIEMDKASWFVNIISKKYPKEALNEAF
                     STLEKELNISKANT"
     gene            15124..16254
                     /locus_tag="PC512_000964"
     CDS             15124..16254
                     /locus_tag="PC512_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003462216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HDF2440733.1"
                     /translation="MNNFEIKTRIKFGEGSLKALQELKNKNVLIITDPFMVKSKTIDK
                     ITSNLINSTYQVFEEIVPDPPIEVVVAGIEAFKSINPDVIIALGGGSAIDAAKSIMDF
                     SKKILKINEVEFIAIPTTSGTGSEVTSFAVITDSQKKCKYPLVSDDLLPDMAILDPEL
                     VKTVPNFITADTGMDVLTHAIEAYVSTNSNDFSDALAEKAIKLVFKYLIKAYKDGNDI
                     EAREKMHNASCLAGMAFNQASLGINHSIAHVLGGKFHIPHGRTNSILLPHVIEYNSSI
                     VGYTNTTYSATAKKYAQIAELVGLGSANIRISVRNLVNEIKKLQKEMNMPTKLTQCKL
                     SLEDITNEEREIAKLAIKDTCTLTNPKVPTEDDIINILKNIK"
     gene            16495..16845
                     /locus_tag="PC512_000965"
     CDS             16495..16845
                     /locus_tag="PC512_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003453843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HDF2440734.1"
                     /translation="MTEESKQRVIQEYVPGKQVTLAHIIANPNEDIYKKLGLVLDKKD
                     AIGILTITPSEASIIAADVATKASNVSLGFIDRFSGSVVISGDVSSVESALNDVLEVL
                     GNMLNFSSTKITRT"
     gene            16853..17302
                     /locus_tag="PC512_000966"
     CDS             16853..17302
                     /locus_tag="PC512_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EutP/PduV family microcompartment system
                     protein"
                     /protein_id="HDF2440735.1"
                     /translation="MKNIIFMGKTGSGKTTLCQKLDQLELKYKKTQSVELYNNAIDTP
                     GEYMENRNLYNALITTSADAKIIAIVYDATQEENYIAPGFASMFCKDVIGIITKINKA
                     TENEVNIAYERLSLAGASQIFKIDTVDNIGLEKLFKYLEKYKNIDEV"
     gene            17404..17979
                     /locus_tag="PC512_000967"
     CDS             17404..17979
                     /locus_tag="PC512_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HDF2440736.1"
                     /translation="MGKKILLVDDEPLLRMDTKDILESHGYEIIGEASDGFEAVEMCK
                     KHKPDLVIMDIEMPILDGIKAGKIICKENIAGGVLLLTSFEDKEYVEKAKSIGAYGYL
                     VKTASEKSLIPTIEMCLNKVNEFEKMKKDLEKVNSKLNERKLVERAKGILIREFKISE
                     DEAYTRIRKLSMDKRTTMMEIAKMIIIGYDD"
     gene            17972..19381
                     /locus_tag="PC512_000968"
     CDS             17972..19381
                     /locus_tag="PC512_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase N-terminal domain-containing
                     protein"
                     /protein_id="HDF2440737.1"
                     /translation="MTNTIKKISTAQTYLNNNEIEKIIEVSKSLDLMASFYEADVFID
                     VLSKFDDEAIVVAHGRPKEKSMYCENVIGKKALIENEPGVIKCLKTGERVRDIKALTQ
                     EYKLVKQNIQPITLDDKVLAVLIVEKDISSEVKNEFNASEDEENKNLHQFIKLIGNND
                     FLVDNLNSAILIFDKNGKLKIKNRIATEIYKNLGFGYDIQDMHYNDLDIETNTFENIL
                     MDENYDETNEVSIGNMFFKIKTIYIKDDEFKVCKIVQDISDLKRKEEELVLKTVAIRE
                     AHHRVKNNLHTVISIIKKQSRLSQNDEVKQCLDNIINRVFAILSTHYLLSKEVDNNIS
                     IREGINLLVSNIQGGYLFSKDIDIRITGEDFKISGEKATAILLVINEILQNCYDHAFS
                     DREHGTIQILINKDNDYRNIAIIDDGIGFDSNNINKNSLGTYIIDSYITQMLKGNIER
                     KSSENGTEVLITIPTQINI"
     gene            19565..20998
                     /gene="eutA"
                     /locus_tag="PC512_000969"
     CDS             19565..20998
                     /gene="eutA"
                     /locus_tag="PC512_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004458698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase reactivating factor
                     EutA"
                     /protein_id="HDF2440738.1"
                     /translation="MREELLSVGIDIGTSTTQLIFSKLIVENTESNFSVPRISIVDKE
                     IIYKSKVYFTPLISNNEINGQQIKDIVENEYKKANISKEDIHTGAVIITGETARKENA
                     NDVLHTLSGFAGDFVVATAGPDLESIISGKGAGAHIYSKEHSTTIVNIDIGGGTSNIA
                     SFKRGEVTDTGCLDIGGRLVKIDKISKKITYISPKIDKIIKDNNLNLQVGTMATVENT
                     KPIVDIMVDLLMESIGLKKQTPLFDFIITNKSISIDENIKNVSFSGGVADYIYYDGEI
                     KDYFEYGDLGILLGQAIKNCEYLKKVNVVKSMETIRATVVGAGSHTTEVSGSTITYTS
                     EKFPLKNLPVLKLSIDEETGTSKQISEAIKNKLNWFKLENDLQKVAIAMIGKKNPTFL
                     DIQEYAKGFVDGMQQIIENDLPFIVIVENDMAKVLGQAIYALLNYEKEIVCIDSVKVE
                     NGDYIDIGKPIVEGKVLPVVIKTLVFN"
     gene            21016..22380
                     /locus_tag="PC512_000970"
     CDS             21016..22380
                     /locus_tag="PC512_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003454054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit EutB"
                     /protein_id="HDF2440739.1"
                     /translation="MILNTKLFGRTYQFKGLYDVMAKANEEKSGDKLAGLAAESAEER
                     IAAKVVLSHIKLEDIRNNPAVAYEEDEVTRIIQDAVNEKVYEEIKNWTVSELREWLLD
                     SNTTSLDIRRISRGLTSEMIAAVAKLMSNMDLVYAAKKIKVTAHCNTTIGEQGTLSAR
                     LQPNHPTDDPDGILASLLEGLTFGIGDAVLGLNPVDDSVESVTKVLKRFEEVKQKYQI
                     PTQTCVLAHVTTQMEAIRNGAPADLIFQSIAGSEKGNEAFGFNGDTIEEARQLALKHG
                     TATGPNVMYFETGQGSELSSEAHHGIDQVTMEARCYGFAKKYEPFLVNTVVGFIGPEY
                     LYDAREVVRAGLEDHFMGKLHGLPMGVDVCYTNHMKADQNDMENLAILLTTAGCTYFM
                     GIPHGDDVMLNYQTTGYHETASLREMFGLTAIKEFDAWMEKMGFSKDGKLTELAGDAS
                     VLLG"
     gene            22393..23274
                     /gene="eutC"
                     /locus_tag="PC512_000971"
     CDS             22393..23274
                     /gene="eutC"
                     /locus_tag="PC512_000971"
                     /EC_number="4.3.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014952556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit EutC"
                     /protein_id="HDF2440740.1"
                     /translation="MNEKDLKALVEQLVGQMLGELDTNVVSETVKKATEVVVDNNACI
                     DDITEVDIRKQLLVKNPKDAEAYLDMKAKTPARLGIGRAGTRYKTETVLRFRADHAAA
                     QDAVFSYVDEEFIKENNMFAVETLCKDKDEYLTRPDLGRKFSPETINNIKSKFGTNQK
                     VLILVGDGLSSAAIEANLKDCVPAIKQGLKMYGIDSSEILFVKHCRVGAMDHLGEELG
                     CEVICMLVGERPGLVTAESMSAYIAYKPYIGMAEAKRTVISNIHKGGTTAVEAGAHIA
                     ELIKTMLDKKASGIDLK"
     gene            23294..23947
                     /gene="eutL"
                     /locus_tag="PC512_000972"
     CDS             23294..23947
                     /gene="eutL"
                     /locus_tag="PC512_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003761789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutL"
                     /protein_id="HDF2440741.1"
                     /translation="MKNDVIRPNILGIKIISNISPEMAQKLELKSHHKSLGLITADCD
                     DVTYTALDEATKASEVDVVYAKSMYAGAANASTKLAGEVLGIIAGPSPAEVRSGLNAV
                     VDFLEYGATFISANDDDSIAYYAHCVSRTGTYLSEVAGIREGEALAYLVAPPLEAMYA
                     LDAAMKAADVKMCELFAPPTETNFGGALLTGSQSACKAACDAFAEAVKSVADNPTGF"
     gene            23958..24659
                     /locus_tag="PC512_000973"
     CDS             23958..24659
                     /locus_tag="PC512_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HDF2440742.1"
                     /translation="MDAIGLIEVIGYVAAIEASDACLKSANVNIVRVDKVGAGIVTLT
                     ICGDVGAVKAALEAGEIAASRVGTLRTSHIIPRIHNEVTNALFKTKEPKVCEVSEDKE
                     KNFEITLEIADNVSKNLSEKENVILDVNENSGDTENLYSDIDKTNKKIETVDDSLTEA
                     NEEKIENTNDKEVLEQVKIENSDFDRDDLSKNSVKKLKAMAKKLDSSITYKDLNVLKK
                     EELINLVKKLSRRDR"
     gene            24662..26131
                     /locus_tag="PC512_000974"
     CDS             24662..26131
                     /locus_tag="PC512_000974"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetaldehyde dehydrogenase (acetylating)"
                     /protein_id="HDF2440743.1"
                     /translation="MTLLDKDLVSIQEVRTLVRRSKVAQEKLSKMSQEQIDKIVKAVV
                     DAAFNNATKLAKMANEETGFGKWEDKVIKNTFASMGVYETLKNTKTIGIIGEDKEANT
                     IDIATPVGVVAGLIPSTNPTSTVIYKTIISLKAGNTIVFSPHPNAKNCILETVNIISE
                     AAIKAGAPEDSILCITNPSIVGTNELMKHKDTNLILATGGEAMVRAAYSSGTPAIGVG
                     PGNGPAFIDKSANVKLAIKRIIDSKTFDNGVICASEQSIVIEKSMEETVLKELKNQGA
                     YVLNEEESERLAKFILRANGTMNPQIVGKSVEVIANLADLTNVPKNTKVLVARENKVG
                     HNVAYSREKLTPILAFYVEENVEAIMNRCREILLNEGAGHTFSMHVNDEELVKRFALN
                     MPVSRILVNTPSALGGIGASTNLVPALTLGCGAIGGSSTSNNIGPLDLINVKRVAYGI
                     KEIEELGRDKSQVEKSMFDSMDKEELINLLVQKLVKELA"
     gene            26227..26514
                     /locus_tag="PC512_000975"
     CDS             26227..26514
                     /locus_tag="PC512_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HDF2440744.1"
                     /translation="MASANALGMIETKGLVGAIEAADAMVKAANVQLVGKEQVGGGLV
                     TVMVRGDVGAVKAATDAGATAAERVGELISVHVIPRPHFEVDAILPKVSAE"
     gene            26641..27402
                     /locus_tag="PC512_000976"
     CDS             26641..27402
                     /locus_tag="PC512_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin adenosyltransferase"
                     /protein_id="HDF2440745.1"
                     /translation="MGVLTENEVKRKIGKNKNNITEFYIEKGQIITPSAKSYLAERSI
                     ELKYVDKLSDVNNEPKEVVKEVVKEKKYKYTTVFGAKLDEKPEHMTQLNGNLLVFKDH
                     KRIILRGKIDSLESEILKVQILCQKLDMPKLVKELQEVLDFVRNIMRCEVLDEKLGDF
                     KLLGLTPQELREQSHYPKKYFGIGHEFPSYEMGEVVVAINSIRSNTREVELAAYEAFK
                     GEYGNVHREDLIKALNRLSSVFWIMIYKVRTNKYK"
     gene            27415..28044
                     /locus_tag="PC512_000977"
     CDS             27415..28044
                     /locus_tag="PC512_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate propanoyltransferase"
                     /protein_id="HDF2440746.1"
                     /translation="MENLLNEIVEEVITRVKKEAFIEVEASGRHVHLSREDVDKLFGE
                     GYTLTKLKDLSQPGQYACKERVTITGPKGSIKNVVVLGPCRNETQVEISLTDGSTLGL
                     KAPIKQSGDLEGTLSIKISTQYGEVELDKGLMVAKRHIHMTPKDAEKFNVCDKEIVEA
                     KVMGQRPLTFDDVVIRVSDSFKTYMHIDYDEANACGYSKGTVAKIIKKA"
     gene            28086..28811
                     /locus_tag="PC512_000978"
     CDS             28086..28811
                     /locus_tag="PC512_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02536 family ethanolamine utilization
                     protein"
                     /protein_id="HDF2440747.1"
                     /translation="MNYDNLVDLITEEIYKKINSNEIKISNKPKAVIVFEQDNNKFNL
                     LKDGFEIVEFDKSIRECEIVIVSRLCMRGLSNIALGNSTSDEERFILKMIMNGKKVYV
                     LDEGIEYKKYKDTAPKALYKKFMSFEDEICKFGVEIIKDLNVITKNKLNIKKELESTR
                     GSKKEDTKVLDKDILNLTSVESVKIDNEFSLDLRNKKLISEADLRKPTINGVKNILVN
                     KKSIITPLAVDFMRIHHLKLKKL"
     gene            28824..29096
                     /locus_tag="PC512_000979"
     CDS             28824..29096
                     /locus_tag="PC512_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EutN/CcmL family microcompartment protein"
                     /protein_id="HDF2440748.1"
                     /translation="MDIGKVVGNVWATRKDEKLCGQKLLVVKILKTKDTYKEGFMVAA
                     DNAGAGNGDLVLISKGSSARESIEKSHVPVDATIVGVVDSFEVFDE"
     gene            29089..29640
                     /locus_tag="PC512_000980"
     CDS             29089..29640
                     /locus_tag="PC512_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HDF2440749.1"
                     /translation="MNKSIGAIEFKSIAKGIEVSNEMIKKSSVDVLYLKSICPGKFLI
                     IVGGETSYINECVDYGIKLGEGYIVDNFVINAISQEILDGFKNKYQKLDSIVSIGVVE
                     SSKICAGIKMLDKTLKSGDLVLVKLQLSFAIGGKLVYIVAGDLSSLEYALKESENVVR
                     EKEVIYKTVIPSVDSQIIKSLIK"
     gene            29652..30743
                     /gene="eutH"
                     /locus_tag="PC512_000981"
     CDS             29652..30743
                     /gene="eutH"
                     /locus_tag="PC512_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutH"
                     /protein_id="HDF2440750.1"
                     /translation="MSINEIIIYVMVVFMVLGAIDKCIGNKFGLGEQFEEGIMAMGSL
                     AVAMVGVICLAPVLADVLRPIVVPVFNILGADPAMFAGSLLANDMGGAPLALELAKDP
                     NAGLFGGLIVGAMMGPTIVFIIPVALGIIEKEDQKFLATGILAGIITIPIGAFVGGLV
                     AGFEVMMVLRNLVPIIIFAVVIALGLLKFENAMIKGFTYFGKGVVIVITLGLAAAIVE
                     ALTGIVVIPGMKPISEGIEIVGDIAIVLAGAFPLVFVITKVFNKPLMALGKVLGMNDV
                     SAAGLVASLANCIPMFGMMKDMDNRGKIINVAFSVSAAFVFGDHLGFTAGFNSNMITP
                     MIVAKLVGGITAVLLAMVIANKTLKKENV"
     gene            30745..31218
                     /locus_tag="PC512_000982"
     CDS             30745..31218
                     /locus_tag="PC512_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF861 domain-containing protein"
                     /protein_id="HDF2440751.1"
                     /translation="MDISNIDKNLIETLVRQIIEEKISGTKDTVDFVRNKDISGITSI
                     KLPTVKVSESDRLDTGNPSDVVYTKDLFTLEESPRLGCGMMEMKETTFDWTLNYDEID
                     YVIDGTLDIIIDGRKVSASSGELIFIPKGSKIQFSVPDYARFIYVTYPADWASQN"
     gene            31731..32252
                     /locus_tag="PC512_000983"
     CDS             31731..32252
                     /locus_tag="PC512_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2440752.1"
                     /translation="MEEIVKKEQASMNDIFLYLKAKSNSLYKFVILYNEFINKPKDYG
                     TGELINMVEVHMLTAIEENPGISPTQLAKIWNRTKGAISQTISKLEKKGYITKEKKEG
                     NAKTILLYPTTSGVELSKAHKLYDTIDVTRTFEYLIKECTLEEIDSFYKVIDLFINLL
                     EESPQENNDSEKV"
     gene            32631..33806
                     /locus_tag="PC512_000984"
     CDS             32631..33806
                     /locus_tag="PC512_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2440753.1"
                     /translation="MNLKQLSEKYEEYVIQMRREFHKYPELSFKEIRTTQRIREELQK
                     IGVPFVSIEPNIVIATIQGKNEGKTIAIRGDIDALPMQEDSDVEYKSEYDGIMHSCGH
                     DAHGAMLLGLAHMLNDIRKDLKGRVLLVFQAAEEVGGGHKEIIQYFKENGGPDRLIAT
                     HVWSDIEAGKISVEPGPRMAGGSGWRIDITGRGGHGSRPDQSIDPIKPACDIVLKVSS
                     IPVNHISVLEQCVVHACAIHGGTTIGNVIPNNAEVIGGYRYFTEESGKKVFDIIKQMS
                     NGVGQVYGVDVKVTHTGGIGPVINDEEAVKMAKEIVSNIDGLELDSYEPICASDCYGE
                     ILKEYSGFYCYLGVGNKEKGIIYAQHHPKYNIDEDILKLGCEFMAKYAVEFLNKNNN"
     gene            33840..35378
                     /locus_tag="PC512_000985"
     CDS             33840..35378
                     /locus_tag="PC512_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HDF2440754.1"
                     /translation="MQGALKENKKKSGGGFLGWIEKVGNKMPHPLALFTYITLIVVAL
                     SAIASFLGFSATSPATGKLIKVMNLISAKGLVLFMQEFVKNFQNFPVLGVVLVMAVAT
                     GVCEKTGFFSTAIKMSLSKVKGNAVVFIIAFIGVFANQAGDAAFVLVPTLAGAIFYGL
                     NRNPLAGIFCGFASVGGGFATAVIPGGWDVTLTPITVSAAQTIQPAFDMTLLASYYAL
                     FVSAFIVATVSTIVTVKFIEPKLGKYTGKPEGIDDNQGFEVTKEQAKAAKLAGFTVLA
                     YVALLIALCIPANSFLRSPEGSLIFGAPLMSCLQFFIVILFFLPGIVYGMRVGKIKTV
                     KDLNDILCQSMAAMAPFIVLAIVIGQFLTLFSVSNLAQVLAIKGGALLNSLPLPPQAI
                     ILLFLVLVAFINIFVISGSTKWMIFGPVFVPMLMQLNIHPAFTQFVYRLGDSVTNHLS
                     PLNAFFIILLATVQKYDKNAGMGTIFSAMIPYTIGYFVVLAVLVVVWMTIGIPVGIGG
                     QVWL"
     gene            35410..36612
                     /locus_tag="PC512_000986"
     CDS             35410..36612
                     /locus_tag="PC512_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDF2440755.1"
                     /translation="METTEIRYNFDEVIDRSGTNCLKYDLKSQFMPESPEDALPLWVA
                     DMDFACAPEIINAMHERIDRKIFGYSSQQTDDYYEAVCGWFKRRFDWKIEKENIFFSP
                     GVVPALGFFTQILTQKGDGIIIEKPVYYPFEDKITNNERKVVNSPLKFEDGHYSMDYD
                     GFEELAKDENNKVFILCSPHNPVGRVWKKEELRKIVDICKKYDLWIISDEIHCDIIRK
                     GEKHIPLEVACPDYKDRIITCTAPSKSFNLAGMQLSNIVINNKELQEKWMLETDSKLA
                     IFLPNPFAIVATKVAYNDCEDWMNQVNEYIDGNIKYVEDFVNEYMPKVKIIKSQGTYL
                     VWLDFRGYGLDAKQLEYVMLNKAKVLLDEGYIFGEEGAGFERINVASPRTIIEECMNR
                     IKCAFEGL"
     gene            complement(36779..37378)
                     /locus_tag="PC512_000987"
     CDS             complement(36779..37378)
                     /locus_tag="PC512_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2440756.1"
                     /translation="MNDNIVEVKNINMNFYTKEGELEVLKDVNFNLKEGEILTLLGPS
                     GSGKSTILNILTNLLKPTSGDIKITGNIGYMFQKDNLLEWRNIMDNITIGLEIQGKKD
                     KKSLDRVESLLKTYGLWDFRSMYPKELSGGMRQRVALIRTLSVNPDILLLDEPFSALD
                     YQTRLLVCDDVYSIIKNENKSTILVTHDIGEARCIKVQL"
     gene            37548..38906
                     /locus_tag="PC512_000988"
     CDS             37548..38906
                     /locus_tag="PC512_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440757.1"
                     /translation="MSNIITNLIESIFTNPITILFLLAITVYSVFKIIENNRVYSFVS
                     SKLDEINRDYKTSEFYKKVRDDYYTYSKENPYADVNITSFIEEVVSDLKHNNLPLLEK
                     IRSIKNSSSISILLGVLGTFVGLSTMLLCVDTKDIINSLPSTISSMQTAFTTSIFGVV
                     FSLIIGYFTKIKDCEHVLIQIMLKSENLLTSEITHFKSERMDLKVEEVKNTIKQISKS
                     IEAIEKFDKISKDLNDFNDEFISGIEALKSLLEGSQSSIKTFDQSVRKLDKQFNILNI
                     KFVKLFDKYDNQDNINKEILFDIKESSKNIYNATESQFKIRDYIKNINAGFALYERSA
                     QDLLTKLMTHENKISQNQKILLDEKFTLDDSIKNLSSIIENFSNDLQVKLDMMFENSL
                     DIQDKLDVMFNNSFMNDEVPLDSEELFKDDVNNVFNPFSEEIYEIEDKEIKVIGEDEL
                     NE"
     gene            38899..39531
                     /locus_tag="PC512_000989"
     CDS             38899..39531
                     /locus_tag="PC512_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HDF2440758.1"
                     /translation="MNNKYRRTVNREFEKSSFWPTFTDLLSTVLMVVILILFSSESIS
                     GSVEQDLAKNVNASVEETFKKSGIPVKVDKSNGQVTFGEKTMFDVDSDVLKPEAKEML
                     KMFVPKYIETIYKDYGDYISKIVIEGHTDDVGSYIYNLDLSQRRAYSVAKFIVGDEIG
                     DYKYKDKVTKHIIAIGRSKAELIKNGDNSVNRDASRRVELKYEININQNK"
     gene            39860..41017
                     /locus_tag="PC512_000990"
     CDS             39860..41017
                     /locus_tag="PC512_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2440759.1"
                     /translation="MIEISIKNKKNSKIKTLILLLIVSISIYLTGCTTLDNGNNQSNN
                     NDSLSSSISSDKNVKIHFIDTGNSDAILIQDGKTFILIDGGDNDDEGLMVDYLNNQGV
                     KDIKYLIATHSHADHLGGLDSVVKNFNIENVFVSNGSAETKSYRDFINALANKGLSPS
                     VPLENNKFYLEDSYFEVLNTNGGDTTNEQSLVLVYTNGNDKVLFTGDAEEGTEKEILP
                     KLEKVDLLKVAHHGSRSSSSQEFLDKVNPEYAVLLVGKGNSYGHPHQETMNKLKKMGV
                     KVHRSDECSDIIFESTGDGVFTSCKDGSYNKGVREDGNSGKSNSNTSKNDSFKNKQNT
                     SNSEEIVYFTPKGKSYHSTKNCSGLSRSKKILSGTIAESKKNDPCDICYGK"
     gene            complement(41164..41799)
                     /gene="lexA"
                     /locus_tag="PC512_000991"
     CDS             complement(41164..41799)
                     /gene="lexA"
                     /locus_tag="PC512_000991"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HDF2440760.1"
                     /translation="MYLDLTEKQVLILEFIKSQIILKGYPPAVREICTAVGLRSTSTV
                     HSHLNKLEKLGYIRKDPTKPRAIEVLERSKVNDVSGANQEIIELPLVGQITAGEPILA
                     QQNIEEYIPFPASLVKGSNNFVLRVKGESMINAGILDEDYVVVDKKNTALNSQIVVAL
                     INGESATVKRFFKEGNLIRLQPENDFMEPIMLNDSEVEIVGIVTGVFRVIK"
     gene            complement(41903..43030)
                     /locus_tag="PC512_000992"
     CDS             complement(41903..43030)
                     /locus_tag="PC512_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDF2440761.1"
                     /translation="MNNDKKIIKVHNKSDKPDNIVIKENELIEKCLLLENKLPVFMKD
                     YFIYLKGSVAVSTRLAYLEDINFFCSYLIETKELTNADCVKDITEDDFNTIKSRDINL
                     FLGDYCSRYYKNTEKNTLIFENNNRALARKKSSISTLFKFLYRNSQIDNNITDGFNPI
                     KLPKPQPDAIKRLEIDEVAKMLESVETGEGLTEKEKVYWRKTKLRDKAILALFVTYGL
                     RLNELRELNISSFNFSRGEFKIYRKRGKEVLMPINHTCEHVIKDYLQNERTRDELLND
                     EEKDALFLSLQNKRITAKAIRTLVKKYTSIPLDTTRDNGYSPHKLRATAATSLIQTGF
                     SIYDVQNLLDHDNVTTTQLYAAHKKNVKRDIVKNFEWIEDD"
     gene            complement(43351..44196)
                     /locus_tag="PC512_000993"
     CDS             complement(43351..44196)
                     /locus_tag="PC512_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440762.1"
                     /translation="MIYIIEILKISVINIFCFIGIFIVFGLIFSITENLNNKFIFSSF
                     GKTGIIVTGAIGTFVHELSHLIMCLIFMHKINSVKFFRPIESKNDGILGYVSHSYKKD
                     NLYQSIGNFFIGIAPIIGGTIMIILIFKILLPDSYMKVTQNIDLKLYVSMINNLNING
                     FIHIILGDISNFIRIMLLTPSVYSLKYFIFMFLMYSISTHMSLSSADLKNSLNGLSFI
                     VIVIFVISSITYLFGFDNLNISSLIVKYNIFISFFMAIGFIFSIVTLIISYILSLVSP
                     FKNFS"
     gene            complement(44226..44597)
                     /locus_tag="PC512_000994"
     CDS             complement(44226..44597)
                     /locus_tag="PC512_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HDF2440763.1"
                     /translation="MKLKLLVEEYAVCRLNNDSKIPTWIDTEKFYSITRTDDELSVVC
                     LNNNIPSDVKSEKEWRILKILGPLDFSLVGILSKLSSLLADNKISIFAISTYDTDYIL
                     VKEKDIENACKILSCNGYEVE"
     gene            complement(44750..45010)
                     /locus_tag="PC512_000995"
     CDS             complement(44750..45010)
                     /locus_tag="PC512_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003866776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein S"
                     /protein_id="HDF2440764.1"
                     /translation="MEVLKVSSKSNPNSVAGALAGVLRERGVAEIQAIGAGALNQAIK
                     SIAIARGFVAPSGMDLVCIPAFTDIEIEGDKKTAIKLIIEPR"
     gene            complement(45199..46143)
                     /locus_tag="PC512_000996"
     CDS             complement(45199..46143)
                     /locus_tag="PC512_000996"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit alpha"
                     /protein_id="HDF2440765.1"
                     /translation="MIENNSEKIKVLENDIKQLITISKANNIDLSDKINSLNEKLEKL
                     KEDAFSHLSAYEKVTLSRDIKRPTTLEYIEHICSNFLELHGDRLFKDDPSMVGGIGQI
                     GKFNVTIVGHQKGRDTKENIKRNFGMPHPEGYRKALRLMKQAEKFNRPIITFIDTSGA
                     FCGLEAEERGQGEAIARNLLEMSKLSVPVITFVIGEGGSGGALGIGVGNDVCMLEHSV
                     YSVISPEGLSSILFKDSSKAKEACDVMKLTSNDLYDLKIIDKIIKEPLGGAQKDVEAV
                     SKEIKAYILERLNHYKDMDKEEIIAQRYKKFRNIGKCL"
     gene            complement(46164..47018)
                     /locus_tag="PC512_000997"
     CDS             complement(46164..47018)
                     /locus_tag="PC512_000997"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HDF2440766.1"
                     /translation="MIKKFLSSKESKYVTISLDDNFKKNSVDDKFWTYCKGCDSHVFR
                     KDIEENSFVCPKCSRHYGLRARKRINLLIDKGTFMEFNSDVEFQNPLNFPKYKEKVDS
                     YKEKTKESEAVVTGYGRINGIKTVICVMNPDFMMGSMGSIVGEKITYSIEYAAENNLP
                     IIICSASGGARMQEGMVSLMQMAKTSQALSKLEEKLLPYISVLTDPTTGGVTASFAML
                     GDIIISEPNTLIGFAGPRVIEQTINQKLPEGFQTSEFLLEKGFIDMIVDRRKMKEVLY
                     QILAMHKK"
     gene            complement(47033..48394)
                     /gene="accC"
                     /locus_tag="PC512_000998"
     CDS             complement(47033..48394)
                     /gene="accC"
                     /locus_tag="PC512_000998"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HDF2440767.1"
                     /translation="MIKKILVANRGDIAVRIIRTCKELGIKTVAIYSEIDKDCFHRYI
                     ADESICIGPNNISKSYNNIENIIYLALKLKCDAIHPGFGFLSENPEFAKQCEDNNIIF
                     IGPTREQMILMGDKSRARETMMELNIPVVPGSESVLKTKEEALEVAREIGYPVMIKAS
                     SGGGGKGMRIVRKEEELFSNFDMASSEALAAFSNSDLYMEKFIENPRHIEVQVFGDKH
                     SNAIHLGDRDCSMQRRNQKVIEESLSPYLSDEERQKLHKIAVDIVKGVGYIGAGTIEF
                     IVDKDKNFYFIEMNTRIQVEHPVTEMVTNLDLIKLQISIANGDKIPFKQEDITFRGHA
                     IECRINAEDSSKNFAPSPGKIESLNLPGGFGVRFDTFVYAGYTIPPLYDSMIGKLICW
                     AETREECISRIYRALDEIIVEGINTNVEFQKALVTSEEFREDTHHTKFIEDVFMKKEF
                     ATL"
     gene            complement(48410..48862)
                     /gene="accB"
                     /locus_tag="PC512_000999"
     CDS             complement(48410..48862)
                     /gene="accB"
                     /locus_tag="PC512_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HDF2440768.1"
                     /translation="MNINEIKELLKAIDSTNLEYVKLESSDLRLEVSKKAQSTSSPVL
                     SVQQESVVDLSLEKPVVNDTPVTSNENLSVVVAPLMGTFYDSPSPDADSFVKVGDVVE
                     EGDTLCILEAMKLMNEITSEIKGEIIEVLVSNEELVEYNQPLFKIKPL"
     gene            complement(49132..49578)
                     /locus_tag="PC512_001000"
     CDS             complement(49132..49578)
                     /locus_tag="PC512_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440769.1"
                     /translation="MESKFFNWYTQSLGGTFGIISCICAYLNGYMFVYTNSASKYFES
                     IGFLGIISSYTLLPLCMLTLIFGVIYSYTPETSDKSIFNIPFFTLNKRLILITVVFGF
                     IGARVYFIIPAILITFNLYSNVLIAKLKYILCKNKENDTNLKESEV"
     gene            49853..50131
                     /locus_tag="PC512_001001"
     CDS             49853..50131
                     /locus_tag="PC512_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440770.1"
                     /translation="MVDTLEFGLKILFFILSIIWMGKIMILRTDKQIVINPLLIGISA
                     VLVMLHTSQSNIEFFGLDVQYIRIVLYIIYSLIILIGIWATNRRNGIF"
     gene            complement(50260..51006)
                     /locus_tag="PC512_001002"
     CDS             complement(50260..51006)
                     /locus_tag="PC512_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440771.1"
                     /translation="MWEGTMNLANLIPFIISAAALSPINSNDKVLSENQLKDIFPDAN
                     LRAVVKRYINPDEMTISNIKALDGEFYATGESISNLKGISYLENVDNFIFWNNNIKEI
                     PKEALSLKDMDSINLANNYLIDDDVVNSLSHNGVDVNCDLNFIDTKDNQYKLDSKYHN
                     VDIAKGESIDLRKIITKKIDSYYKYWEVTDNLPKDLNFIVSVSDKSVLSCEDMIIKGN
                     KTGQAVVKVILSDKNDLNTSQEVLITVNVK"
     gene            complement(51135..51779)
                     /gene="trmB"
                     /locus_tag="PC512_001003"
     CDS             complement(51135..51779)
                     /gene="trmB"
                     /locus_tag="PC512_001003"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HDF2440772.1"
                     /translation="MRRRRKKGADEKLLSYTKYVLRDDIDKLKGKWNLKFRNDNPIHV
                     EFGTGKGKFITTLAKQNPDINYIAMELKEEVLLKAVEKADASNLNNILFLWGDVSNIL
                     DYFEAKELSRIYINFCDPWPKNRWSKRRLTHSGFLEMYNRVLEDDGEIHFKTDNEKLF
                     EFSLNEIAANNWLLKNISLDLGNSEYENNVTTEYEDKFMSQGMRIFRCEAKKRN"
     gene            complement(51917..52237)
                     /locus_tag="PC512_001004"
     CDS             complement(51917..52237)
                     /locus_tag="PC512_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein HesB"
                     /protein_id="HDF2440773.1"
                     /translation="MKITLPETAIDTLKSILKDNQDKPNNIRVYFAGVGCGGPSFGLA
                     LDEKKEDDLTYEVGELQFVMSSDEYSQYGDIIIEDTGFGFRVIPENMKDQGGGGCSGC
                     SGCH"
     gene            complement(52690..52938)
                     /locus_tag="PC512_001005"
     CDS             complement(52690..52938)
                     /locus_tag="PC512_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDF2440774.1"
                     /translation="MQKTKAWGIIEPEKPESQQQMAHMDFAVNDLEEAVQYAIHCGAT
                     IAEEQFTDDWRVMIDPAGHPFCLCQMKSIMESSHFSLL"
     gene            complement(52969..53430)
                     /locus_tag="PC512_001006"
     CDS             complement(52969..53430)
                     /locus_tag="PC512_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase/bleomycin resistance/dioxygenase
                     family protein"
                     /protein_id="HDF2440775.1"
                     /translation="MKFGGVLLIVKDINKSKKFYEDVMEQKITLDLGEHVSFENGFGL
                     QSNYKAIIGYDLPIYQQSNNFQLYFEVNDIKQWESKINRIGNIEFLHYIKEYPWGQRT
                     FRFYDFDKNIIEISESMESVIKRLLKQGLALEEISKRTMYPVEFITQFQQL"
     gene            complement(53468..54301)
                     /locus_tag="PC512_001007"
     CDS             complement(53468..54301)
                     /locus_tag="PC512_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2440776.1"
                     /translation="MLKKESIHFINKNRSLIVCEDNFVYLLPCIQLRNWISNFTISFP
                     NQTIISDNYTIIPHGSVTLVFFYDATGLHSLLFGPTTKPKTVGNIANRCDVILIIEFQ
                     PAGFFPLIGIQQSELIDKVVPFSIINTSLDLEIKKIFNESLSIDKLILKLEELLISNI
                     KIEYSYEFILAIQLIIQNSGNISSQEISKKVFYSSRHLNRLFNQYLGLSMKSFSRLVR
                     INKSIKLLNNNKTSLMSICNELGFYDIPHFIKDFKIVCGITPQKYRANMSDFYSEIAK
                     F"
     gene            complement(54575..55261)
                     /locus_tag="PC512_001008"
     CDS             complement(54575..55261)
                     /locus_tag="PC512_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2440777.1"
                     /translation="MKITHNSLAVEAKNIIKEYKIGNTTTRVLKEVSLQVMKGEFVSI
                     MGQSGSGKSTLLYILGGLDTPTSGKVYMNGADISHFNDEKMSIIRRRNIGFVFQFYNL
                     IPNLNVEENIMLPLLLDGKNLKDYKNQLDEILDIVGLTDRRKHTPRELSGGQQQRVAI
                     ARALIGKPEILFADEPTGNLDSKTGIEIIDLLNKINRDNGQTIIMVTHSPEAAKSSSR
                     TITVSDGLIV"
     gene            complement(55276..57753)
                     /locus_tag="PC512_001009"
     CDS             complement(55276..57753)
                     /locus_tag="PC512_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDF2440778.1"
                     /translation="MKIILKYIFTNIKERKIRTAVMLLSIVLSTVLLFVSFSIGLSYE
                     SAQRKMAKGMYGTATISVQSKNPDILTNLEDIPDLNAIKSKVGVLESSAIYNKGGYYE
                     EFSLISADLSQLNKINKPRLENGDSITDFSGDKIILPNRFTSKYKIKKGDSITLQIYG
                     KSYTFQVSDIASYDTVFLRNTRGVNALLPKETLSKIINKGSGYTRVLIESEEEITENL
                     VNKLSKELSTEKYMVSNTINETKIISDARQKTMPFFLISFFALTLSIFIIYSSYKVIT
                     LERLPFIGTFRSIGANEKTVTRILMLESILYGSIGGLIAIPIGVVVLNLMLHGLGNSL
                     EQGISIPVVISPIGVIISVIVAIIVSSFSAYIPVKKASHLPIKNIVLGTVEEKNVSNR
                     SILFIGSIMFILSILLPRISPENTLYLAGGFSLLGLIVATIVLIPLITDIMSIVFEFV
                     YKNILGNEGKLAARNMKNNKNIIQNITLLFISISAVIAISVVGNFVKTYITDVFRDAE
                     LQGFADGKMNEEFIEDVRHMDGIKKILPLYVMNNEISGNGVTLSRLEGTDNIKLYNSM
                     FGINYTNFEIKKQVIEAFNDKRSVILNEDTLKKVGLSIGDTITLSNDKYDFSYKIVGS
                     FKSRANDVEAVIPSHYAVNDFDKTNYGFLVYTAVNPDAVMIQIRYLFGDTYNWSRTVE
                     EFNNDSLNTISSFLSPMNKMTYFIFLLATVGIINNLLINYIQKRRSIAMYKSIGLSNK
                     QNIKVTLIEGFTSGLLGAVIGIVISILEIQTIFIVAGPKISMKPDLDFKTFIIVGLLG
                     IIVTLIGSIVPIIKGKKMKLIEEIKFE"
     gene            complement(57972..59375)
                     /locus_tag="PC512_001010"
     CDS             complement(57972..59375)
                     /locus_tag="PC512_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2440779.1"
                     /translation="MHKPSYKTVFHSYIIFFMIFICLILTVIGIFLSLITIQKPNGEF
                     IRSDWPKKFTENFNEQIVFIDNKPQVKQSGLEKLRENQLWLQILDSSGNRVYGFLEPK
                     EHKDYYSNSELLALANQNNSSNGTVYFNTIKNNKNDYIYIIYFPLNISKVNMFFDGGK
                     FIGGKSIVFSIIGIIFLIILVSGIAYGYWVTKCISNITSAVSDISKRSYLPVNIKGVF
                     ADIYNSLNILNEEIHRSDEIQNKTDIMREEWISNITHDLKTPLSPIKGYAELLTDSST
                     NYSPEKVYKYASIMLKNIEYTNTLINDLKLTYQLKNGIIPLNKNNYDLVRFLKELSID
                     ILNYPEYESNIVEFKSNIDNINFDFDCTLLKRAFSNLIVNAFTYGDKNTKVCVHITLN
                     ERIEIIISDNGKGMSREEASNLFNRYYRGSNTKQKIEGTGLGLAITKQIIEVHGGNIS
                     VESIPGLGSSFYITFPI"
BASE COUNT        21891 a         8321 c         9436 g        19815 t
ORIGIN      
        1 atcagcggtt atctaacaaa gaaattgcag gacttgaatg ttgatactat tagaaccgat
       61 atactgacta gccccacagt tacagatgta attgtgtgga atatcgaaca gtcgggaacg
      121 gacacttttt ctgctaccta cgaagtagat cagcagataa aagagggaga acagacaaca
      181 acagtcaagg caacctatac ggtaaaagtc catgtagacg ctgacaggga tatggtaatt
      241 attcagaacc ctacccttgc accagcaatc gaaaaatcgg actatgagcc aaagacacca
      301 gaagcagacg caagtgtaga cgctgatacc gtgaatgacg ctaccgcatt tctggaaaca
      361 ttctttaagc tgtacccgac agccacagca aaagagcttg cctattatgt atttggaaat
      421 gtgcttgaac ctatcggcag ggactacctt tattcagaat tggtaaaccc agtacttaca
      481 aaggacgggg ataatatgaa agtcaaggta gctgtaaaat tccttgataa tcagacaaag
      541 gcgacgcagg tattgcagta tgagcttatt ctacataagg atagtaactg gaaaattatt
      601 atgtaagaca ttttgttggc aggatctatt ttcggatata gtctgccttt tctgtagcaa
      661 atgtactgca ctgacaagct atttcattgt attttaagca attaaacctt tcttgacaat
      721 tttatcttaa atcatatatt tatggatatt gactttctgc ttgcaataag ctataatatg
      781 actataaaat caaatcagtc atataggagg tatgtggtat gtataaagaa gttggtattt
      841 cttcaaataa tgttccgata acactttcta tctggtatac agaaagaagt agtcctacca
      901 ttgttttttt gccgggtact atgtcacacc ctctcatgta tgagaatttt ctatgtggtt
      961 tgagtgaaag aggatttaat ataataggca ttcactatct ttcacacgga aaaagcccta
     1021 aaatcaaaaa aaattataca atggaagatt tgctgcataa tgtatatgac gcaacaactt
     1081 acggaataga aaatttcggt gaaaacatag ctgtcatggg ttccagtcaa ggcgggattt
     1141 tagctgcaat ggcggcaggt agggacacaa ggttaaaagc cgtttttcca cataatatca
     1201 tgctgaccac attaaaagaa actatgagct taacaaaata tcccacatgg tcgcaccgtt
     1261 ttatggggct gatacagtgg ggctttcgtg taggtggaaa attgctgcct aactacaagg
     1321 ttccaggaga cgcttattta gactatgaca gagtatttta tagtgaacag gcaaaacaag
     1381 attgcttaaa tgaccctatg cttttaccct attatccttt aagatttgtc accagcttat
     1441 ttaatgctga cttatcgtgc ctggagaatg gggctataca atgtcctgtt attttaatta
     1501 ctgccaaagg cgacccgctt tttagctttg attataccaa caaagtattt gatttaattc
     1561 atgtaccgca aaaggaatta cttgctttag agcttaatcg tcacatgatt tttaatgagg
     1621 acacggacac tacaataaac gcattggaag ctaccttgca taaatatctt ggatagcata
     1681 ttgattatat aatcagtaaa tgttatactt ttcatgacga tataaatatt ttagtcataa
     1741 ggaggttatg agtttgccac gatttacgga acaagaaaaa gaaatcataa acagtaaact
     1801 tttgatagag ggagaaaagc tgtttgcatt acacggctta aaaaaagtaa cagttgatga
     1861 tttagtagct gctgtaaaca tatcaaaagg ttctttctat gctttttatc ccagtaaaga
     1921 acatctatat gttgaaatca attttcgctt acaaaaagag ttatttacaa gtatagaaac
     1981 aaccattaaa aagaaaaagt ataagaacca tagagattta gcaaaggacg ttatcatgct
     2041 aagtttaacg ggggtgatta cttcgcctat tctttcacag attgatttat ctttaatgga
     2101 ctatctgcaa agaaaaatat cgtcagatat ttttgaaaat catatgtaca gtgatattcg
     2161 tatattggag atattggaag atttaggggt tgtatttttg gttccgcata cggttattat
     2221 aaaatccctg tattctgtct tatcctgttt ggaacaattc aaagaggacg aagaactgaa
     2281 tatgatacaa aatcttttag tgaatggtat tattcagcaa gtagtagcag agtaacaatt
     2341 ttgtttggtt atttgacagg caggtagcca aacaaatttt ttacagttta tatgactata
     2401 tatctataaa cgtcataaag ttaaaggagg aatgaataat gattgatgta aaaaaactgt
     2461 attttagcta tactgacaaa ccgtttgtgg agaatgtaag tttccatgtt gggagaggag
     2521 aaatttttgg ttttttagga ccctctggtg ctggaaaatc aactattcaa aaagttttaa
     2581 ctgggcttaa tacaagatat aaaggcagtg taaaagttgc aggtacagaa ataagggagc
     2641 atacaaatca gttttatgaa aatattgggg tagactttga attttcaacc tgctacgaga
     2701 aattcacagc acgacaaaat ctcgcctatt ttgcttctct atatgaaaag caacctcggt
     2761 ctattgatga attattgcat atggtaggct tggaaaatga cggggacaaa aaagttgctg
     2821 acttttccaa aggtatgcgt tctcgcttga atttcattaa agcgttagtc catgaccctg
     2881 atatattatt ccttgatgaa cctacaagcg gtcttgaccc tacaaatagt cgtttaatga
     2941 aagatattat tcttgcggaa aagaaacgcg gaaaaacgat tatcattact actcacaata
     3001 tgtttgacgc aacagagcta tgtgaccaag tagcctttat cgttgccgga aaagtcagtg
     3061 cattggatag cccgcataat ttgattatgt caaggggagc tgccaaaata caatatacct
     3121 actatgataa aggcgagaaa accggagaat gtctgcttga tagaaccaca gaagataagt
     3181 tgttaaaaag tttaatttcc gaaaaccgtt tgctttctat tcatagtagt gagcctacat
     3241 taaatgatat ttttgttgat attacaggga ggacacttca atgagattgg gacgtttaat
     3301 ttgtggtgat atacatttcc aatggaaata tggtttctat tttatctact ttatattaac
     3361 agttttatat gtgtgcggga ttgccgcttt gccggaacat tggaaaacgg atattgcttc
     3421 tattatgatc tactctgacc cggcagcaat gggattattt tttatgggag cgattgtcct
     3481 cttagaaaaa agtcaaaagg tgttaaatgc tatggtggta tcccctgtaa aaatatcgga
     3541 atatatactt tcaaaaacag ttgcgttgat tgctatttct acggtaatcg cattgatatt
     3601 aggggtagtt tccggcagca atcatttact gggtatcgca gttggtacgg ctttgacctc
     3661 agcaatcttt actatgcttg gaattattgc agctacaaaa atttcaaact tgaaccaatt
     3721 tctcattgtg attatgccga tagaaattat ttgctttgta ccacctattg ttggtctgtt
     3781 tgtgaagtta ccatatctgt tccgcttttt tccattcaca gcttgcatga accttataac
     3841 tggaaaaagt gttttactat cgtttgatat ggtacttgta attgctacgt tgattatcct
     3901 ctacatagtt gctcgacata cagttgagca tatgtggaaa agtttgggag gtgtaaagct
     3961 atgaaaaaga tattatccag caccatacag atatttaagc aaatcaaaag tgaccctatg
     4021 atgtttgcgg cttgcttctc cccttttatt atggggactt taattaagtt tggtattcca
     4081 tttcttgaaa gaataacgaa gttttcttta caagcgtatt atccgatttt tgatttatta
     4141 ctttctatca tggctcctgt attgctctgc tttgcatttg caatgattac attggaggaa
     4201 atcgacgata aagtgtcacg gtacttttcg attacccctc ttggtaagtc ggggtatctc
     4261 tttacaaggt tgggagtacc ctcaattatt tcggcggtca tcgcttttat tgtactgtta
     4321 cttttttcat tagaaaagtt gtccattgga atgacaatat gtttggcgct tctcggctca
     4381 gtacaggcaa ttattgtttc acttatgatt atcacattat caagcaataa attagagggt
     4441 atggcagtta caaaactagc tgcacttaca ttgctcggaa taccagcccc cttttttatt
     4501 gatagttact accagttcgc ggttggcttc cttccatcat tttgggtagc gaaagccatg
     4561 cagaatgaag cggttcttta tttctccata ggattggtgg tagctttagt ctggtactac
     4621 ttccttacaa aacgtctgtt tcggaagctg gcaggataag gaggcatatt atggaaaaag
     4681 gtagacttct gcaaaacaaa aatatgaata aggctattca ggtttccaaa attacactaa
     4741 tcatcaatct gagtttatcg ctacttaaat ttgctgccgg atatatagga aagtcaagtg
     4801 ccatgctgtc ggacgctgta cattcggctt ctgatgtagt aagcacaatc gttgtgatgg
     4861 ttggaattaa aatatcagaa aaacagcctg atagagaaca tccttatggg catgaacgta
     4921 tggaatgtgt ggcttccatt attctctctg ttgcattggc tataacgggt gctggaatag
     4981 gatattcagg tatcaagaaa atcttttcag gacagtacaa tacgctttct gtccctagtg
     5041 gaatcgcact tacggcagca gtcttatcta ttgttataaa agagtggatg tactggttta
     5101 caagaagtgc tgcaaagcat acaaattctg acgcacttat ggctgacgca tggcaccacc
     5161 gctctgatgc actctcgtcg gttggttcct taattggcat tttaggagcg cgtttaggct
     5221 atgctattct cgatcctatt gcaagcgttg tgatttgcgg ttgtatctta aaagctgctt
     5281 tgaacatttt caaagaaagc attaacaaaa tggtagacca tagttgtgac aatgctactg
     5341 aaacaaggat tagggaagtt gtgcttcagc agcaaggggt tgatggtatt gatgaattaa
     5401 aaacccgcat gtttggagcg aaaatgtatg tagatattga aatattagct gatggtaatt
     5461 tagctcttta tgacgctcat agaattgctg agggagtcca tcaaacgatt gaaaacaact
     5521 ttccacaatg taagcattgt atggtacatg ttaatacgaa tgaacttctc tattctgcat
     5581 aggacaggga agatgattta aggctattga aagggaaagg agggaagtag gttatggaac
     5641 aatactggtg gattatcatt gttgtggttt tgattgtcgt tggcttactt aaaattgtaa
     5701 ttatgaagaa gtataaccaa aggagaaatt ctaacaatcg ttcaaaagat agcgaggacg
     5761 acaagatgta ttaaggttta ttgaaatctg ttatgttgta gaatgatgtt tttagatact
     5821 agaaagtgct ttaagggggg ctaacgttaa ggaaagcttt gagtacaatt ctttacaatc
     5881 aacagtcttt tgcatagaga aatgtatgta ggaaatatgg tgcaaggcac aaaacaccag
     5941 caattgagaa atcaacctat gaaccaaagg cacactacat tttatactac ttgacaagta
     6001 aacgaacatt tactttaatg gtttaaagaa gtaaacgttc gtttactaaa gaaggaggtt
     6061 gtaaatgtct gacacaaaag aaaatatatt aaaaattgca ctacacttat ttgcagtgaa
     6121 tggttatgag gctgtttctg ttagtatgat tgcggaagcc ttgggaatga caaaaggagc
     6181 attatataaa cattataaaa ataagcaaga tatttttgac tgtatcgtag aacgtatgta
     6241 tcaaattgat aataagcgag ctaaggatta tcaagtacca gaaagcacaa tagaggtaac
     6301 cccaaatgca tacagaaata caactattgg aagtctaata acatttactc ttgcacaata
     6361 cgatttttgg gtgactgatg aatttgcgtc taattttcgc aaaatgttaa tactagagca
     6421 atatagaaat ttaaaaatga atatgcttta tcaaaaatgt cttgtaaatg gtcctatcag
     6481 ttatatagaa gatatattta atgaaatgat tgaaaaaggt gttcttcaag agtgtgatac
     6541 aaaacagctt gctattgaat attatgcgcc attatttcta ttgataagtg tagcagacgc
     6601 agttgaaaat tgttgggatt taaaaactca attaactaca cacgttaaac aatttgtcaa
     6661 gaaatatatt ataaatgaga aagtaaaata atcctttatt ctgtcctaaa tataaaccta
     6721 actttttaat ttcagcagag aaactcaaaa tgaatattgt tataagtcac aaatattaac
     6781 tattaaaata ttacaataac ggagatgaga aaatggaata tattcgcagt aaaaaatatt
     6841 ttacacccga cttacagaca aaaattatgg ggccgaatcc tataaaatta caagaggaac
     6901 tattacaaaa tcataaaatc ccgtctggta gctatgtctg tgaccttgga agtggacaag
     6961 gtttaacttc tgtatttctt gcaaaagaat atggatttgt tgtttttgca gttgacttat
     7021 ggagtgagcc aaaagaaaat gaagaatttt tcaaaaaaat gggattatct tctgcacaaa
     7081 ttaaatctgt aaaagctgac gccaatgaac ttaaatttga gaaagagttt tttgatgctg
     7141 tagtaagtac agattcatat aattattttg gacgtgaccc tatatattta gatgaaaaat
     7201 tgcttccatt tgttaagaaa ggtgggtttg tttatatcac agttcctggc atgaagaaag
     7261 attgccatga gaaacttcca gaagagttat tgttatcatg gacaccagaa gaacttgatt
     7321 atatacatga tataacatat tggtctaaca taattagtca ttgtaaaaag gcagatttaa
     7381 tttcaatata tgaaatggaa agtaattcgg aagtttggtc ggattggata aagcaaaata
     7441 atgaatatgc aataaatgac cgtaaggcaa tagaagctgg cggtggagat tatctgaatt
     7501 ttattgctat aattctacaa aaaaaataaa ttctttagaa ccaaacacta taatttgcgt
     7561 tctaatatgt ttaccgattg acatcaataa ttttatcttt gagggtaatg atttgaaaat
     7621 agaagaatac aagaagatac gaaattgata aattagaatt tgatgggatg gtgatattat
     7681 gaaaatatta tggatcatta ttattatggc agataatctg ctgccgttac tgcttgctcg
     7741 tttctatcca aactataagc ataaagaaat ggcactatct gtccttggct ctcgtcaaag
     7801 cccggtgaaa tggatatata atgtgtggtg cattatatca ggtgtggtat tttgtatcgc
     7861 tccatatgcg ttgtatcaag agaacgatag cggatgggca atcgctatat ggatgcttct
     7921 tgctatatac ggcatcgggt gtgaaatcat ttccggagtg tgcccgttaa atgaaaatag
     7981 acaagacgaa gatataatta caaaaattca cggcggcaca tcggcaatcg gatttatggc
     8041 cttgcttgtc gttcctttgc tctttgcaat tctgcaattc caaacaacaa aagtagtgtt
     8101 aggcgcaatt tcactggtgt gctttacaat agcattcata ttcttctgct tttttattat
     8161 gggtgagaag gaaaagtttg caaatactgt tttgagatat ggcggtcttt ggcaaaggct
     8221 tgttttaata agttgttata taccgttatt tgtttggtct gtttctaatc aataaaattt
     8281 agtttatagg aataacaaat tccagtttgt aaaagtcaat aaatccaaag ataaatttgt
     8341 atttgaaagg agttttgaag aatgaaaaaa tatgagtatg tagaaattaa ctataatgcg
     8401 aaaggagttg tattcctttg tactgataaa cacaaagaaa ttattgacag ttacgcaaaa
     8461 acggggtatc actacgcagg gtttgtaccc acagaaattg acgcaaaagg ctgtatgcga
     8521 aagatagatt taatttttga aaaagaagat taacttattt tagggagttg gttctaatga
     8581 taggacttaa aagacgagat atgaattata ttatgaaagt tggtgctaaa gctcaaggtg
     8641 tttctgtatc tgaatttagg gctatgctac aagataccat agacaaaact atggaaagta
     8701 cagacccaga cgtgcaggca aattttaaac gatactttgg aaataagcgc ccaacaccag
     8761 aggaatatat ttatacgatt accaaaaaga caaaggttaa ggtttaaatg ttgtaaaggg
     8821 ggcttgccgt atgaaacgct ttatgtacaa ttcagtatat tcaagcccaa tttaacagca
     8881 tactatttac aattaaatac gctataccag tagctcgtac aaaatttata ttttgtgcgg
     8941 gcttttttaa tacccgaaaa gtttttttaa ttattttcat ttttttggaa gcaaatcaca
     9001 ccttgctgta cagatatggt gcggaaagag ggataaacac ttttcaattc atagctggaa
     9061 aggaggtgag attatgaaac cgtctgactt ccaaaaaaca attcagtgtc agtttgaatg
     9121 taagctgaaa aaagttgtca aaggtattat ctggaactac cgtaaagaat taaaacgaag
     9181 aaaaaacaag gaaatatctt ttagcgaatt accagacatt acggtagaaa gtctggcaac
     9241 atgggacgac tacgaaacaa actacacaat ttttaatgtg tgtggcatag atattaaagt
     9301 ccttgatgat gaacttgcag aagctctcaa acagctaccc gaaaaaaaac gtaacaatgt
     9361 attgatgtat tacttcttgg aaatgagtga tacagagatt gcagatatta tgaattatac
     9421 cagaggggct gtgttcaaac acagacaccg tgcactagaa actatgaaag agatactaaa
     9481 ggagaagaaa tagaaatgaa gaaaaagtac aagcacccgt cttattattt gatttcatca
     9541 gctatggatg gggatgaaac tgcgattgag aaattactgg cattctatga cccgtacata
     9601 tcaaagtgtt gtttacgtcc tttatatgat gaatacggca atgtttatat tgttgttgat
     9661 atggaattaa agggacgtat tcgagaagcc ttaatcaaaa tgattttaga ctttgagatt
     9721 gatatagata tagaaaccga agaagaataa gcaaatacca gcagggcgtg attggttaaa
     9781 ttcccttctt tcctgccctg ctcctgcttt tatacatgga agcctacggc tttcgccgat
     9841 tgttctttga caactgaata aagcagacag atacgtttgt gatacagcga gccacgggga
     9901 ctgtacgcca tgacctttcc gacaagaaag cgagcgaccc acgcagttga tccgagagcg
     9961 acttgtggaa tggtcgtttt gccatgacct gctatcacag aataatgata cgtccgcatg
    10021 gtgcggttct gcccacaaga atgggaatag ttgagatact aacggagctt tccaaagccg
    10081 tctgtctgct tatgataaga cacacagaaa ggagttgttg caacatgaac aatactgatg
    10141 tgccgatttg ggaaaaatac acccttagta tagaagaagc gtcccgatat tttcgtatcg
    10201 gggaaaagaa gttgcgtaaa cttgccgagg aaaatctgga ctctggttgg gttatcgtta
    10261 atggaaaccg tattcagata aagcgaaaac agtttgaaaa aattattgat acactggacg
    10321 aaatctgatg tcttagagcc gtagatatgg tataatatta gtagcgtatc acggctcatt
    10381 ccatgacgga aaggagcttt acactatgtc aaaaatgaaa agacaagaca gtaaaggacg
    10441 caatttgcgt cttggagaga gccagagaaa agacggaaga tacgtttata aatataccga
    10501 tatattcggg aagccacagt ttgtatatgc ttggaaactt gtaccgacag acaaaacacc
    10561 tactggaaaa cgtgatgata aatcattgag ggaaaaagaa aagcagataa aaaaagacct
    10621 tgacgacggt atcgacacta tcggcggtaa aatgacagtc tgccagcttt atgcaaagaa
    10681 gaacaaccag aaaaagaaca tcaagagaaa cacggaaata ggacgacagt atcttatgaa
    10741 cgcactagaa aatgacccat taggtatgag ggcgattgat acagtcaaac agtccgacgc
    10801 taaagaatgg gctatcagaa tgaatgacaa aggttattcc tataagacaa tagataacta
    10861 taagcgttcc ttaaaggctt cattctatat ggcgatacaa gacgactgta tcagaaaaaa
    10921 tccttttcat ttcaagctaa gtgatgttct ggaagatgat acagagccta aagttatctt
    10981 gacaccagag caggaagaaa aacttctttc ctttatggaa acggataatg tttacagcaa
    11041 gtatcgtgat gaagttattc ttctgctgga aacgggactt cgtatctctg aattatgcgg
    11101 actgacaaca cacattgata tgcttaatcg tgtgattaac atagaccacc agctattacg
    11161 tgatacagag gtgggctact atatttccac acctaagaca aaaaacggca agcgagagct
    11221 tccattgaca gaaagagcat atcaggcact tgaacgaatt ttaaagaacc gaggaaaagc
    11281 tcaaccgctt gttgtagacg gttatagcaa tttcttgttc ttgaaccgtg agggcttgcc
    11341 aaaggtagca ggaaattatg aaagtatggt gcgtgggctg attaagaagt acaacaagac
    11401 ccatgaggac aagttgccga acatcacgcc ccactcattc agacatacct actgtacgaa
    11461 catggcaaat aagggaatga accctaacac cctgcaatac atcatgggac acgcaaacat
    11521 aaccatgaca ttagggtatt atgctcacgg tactttccag tctgcaaagg cagagttgga
    11581 aaggctggct tcttaatatc gaaaatgtat cttactactt atttactact tttggttgca
    11641 ttttcatgct ggtaaatgcc agcttatgcg aggtatcttc caaaaagaaa atgcccatac
    11701 agcccgaaaa tacgggatat atcggcattt accaacttat gaaaagataa tcagaaatta
    11761 gtaagttttt atatcaaaaa aatgattact gtaaagaaat cattttttat tataatcact
    11821 gatacatcaa atattctaaa taaaattttt atttatctgg aattgtatat tttttctata
    11881 atattaacta cagcgtacat tgcccaagca cagatagcca atacaaatac tcccatcatt
    11941 actaaatcta atttaaatac ttgagaacca tatactatca agtagcctat tccatatctt
    12001 gaaactaaaa attctccaac tattacacct acccatgcca taccaatatt aattttagtt
    12061 aaatttatta aatttcctgt gtttgcaggt aatatgagtt taaataatat ttgagattta
    12121 gtagctccaa aactttttaa catcttaatt ttttcttcat ctatattcat aaaataatta
    12181 taagctgaaa gtatagtaac aacaacagaa atcgttacag ctgttacgac gattccttct
    12241 attccagcac ctacccaaac tataattata ggagctaaag cagtcttagg aagagcattt
    12301 aaaactacca aaaatgggtc taatattttt gataattttt ctgaccacca aagagcaatt
    12361 gctaccaaaa tacctaatac agtacctata acaagaccaa gaacagtttc atatacagat
    12421 attccaatat gtttaaataa ttgaccacta aatgcatatt gaataaataa attgtaaata
    12481 tcacttggtt tgctaaatag aaatgtattt ataacattta agtcagctaa aagttcccag
    12541 attacaataa aaccaattaa aattaatagc tggtagaata atacatttct tttttctctt
    12601 tttacacctt taacatagtt tatatatcct tcagatcttt tattaagcct catgtgtatc
    12661 tagctccttc cataatatgt cgaaatactt ttgaaaatca ggaactttac gtgttttgag
    12721 aggcgttttt gttccatcca tgttaagttc aatatcgtaa atatttttta tggtagctgg
    12781 tcttttagat agtattgcaa ccttatctga tatgcttatt gcttctgcta tagctaaaaa
    12841 agtgcaacta attgcttaaa gaaacagaat tatcaacttc agcacccata taaacaatat
    12901 taagatttcc taaactgcta tcccaaacga tactattaat aatagtagat aataacaatc
    12961 tcttatcatc taaactggca ttatcaactt catcattaaa tctcttcaaa ttactaacaa
    13021 taatatcaat attaatactg tcactactaa tattgatgtt actagattcc aaaatattaa
    13081 tcttatcctt taaaatacta atctcattat ttaggctctc aatctgggaa actatataat
    13141 cagaagcagt actaccagta ttttttgcaa gctctataac taaattttta ataagtcttt
    13201 ccttatctaa aatttgattt ttaagtaaat tagtctcaga tttaaaaata ttaaaaacat
    13261 tatcagtctt aatgttatta ctattgaatg cacttataat agactcttct ttacaattct
    13321 taattttatc tataactaaa ctttcaacta atggaccatt aagattttta cagttgcaac
    13381 tatcagaccc aagtgttttt ttagtaccac aaatataata atactttaaa tccttgtcag
    13441 tttttttgcc tttataggta attctcatat tagaaccaca tttaccacat tttataagac
    13501 cagataaaag agcagttttt ccagttgata tccttggagt tttatcacga tttttatcta
    13561 attgattttg tacttcaagc catatttcag gttctatgac tccatggtgt tttgcaattg
    13621 ctgctattga gttagatgta tttttagcat aggtaaggat tccacatttt ctatctggag
    13681 tacctacaac atccatacca ctatttttaa ggtaatctaa aatttcatca ttagctttta
    13741 catatgctgg atttctaagt attctagata aagaactagg gtcaaatttg ccaccacgag
    13801 gaccccttat tccattatta tagacatatt tatataactt agataaggac ctaagttcta
    13861 aatatttatt gtatattagc tttacaatct ccatttgttc atcatttact tgaagcttat
    13921 acatacttct ttcttttaga ttttcatcta agaatgtgat tttttcactg ttgaatccat
    13981 gaggtgtatt gcctccaagc catctaccac tacgggctaa ttcatacata ttgtctttta
    14041 tacgttctgc tattgtttct ctttctaatt gagcaaatac acttgatata aacatcatag
    14101 ctcttcccat tggagttgaa gtatcaaatt gttctttgat agatataaat gatatgctta
    14161 gttcatttaa tttttctatt aaagtagaga agtcagatac atttctcgat atcctatcta
    14221 atctataaca aactaggtaa ctaaatttct tatctttggc atcctgcatc attttcttaa
    14281 attgtggtct atctatattg ctaccactaa atccctcatc ttcatatatc aaaaaatctt
    14341 ttacaccaat agactttgca taatcaatac ataattgtat ttgattttct atagaatcac
    14401 cttttccagt aaatcttgat tttcttgaat aaattgcagc tttcaaaatt aaaaccccct
    14461 ataagttagg atatatattt gaaactattt atctacaacc ttttaagtaa acttattaga
    14521 atgaatttat taattaggta aatttatata attctacttt ttataatata tgactattta
    14581 ttttatttct ttactattca agttctaaat caataataaa ttttgatatt taattgtatc
    14641 aggacaaatc tctaatttca tagattatta atataaaatc ataggttagt gtgaaaaagt
    14701 tgaaatttaa atattttaaa agataatttt tttgaactaa taggtataac aaaaatttat
    14761 agggggattg catatggaaa tcaatgttat agaaattttc cctaaagata aagctaaact
    14821 taataaaata gaaatggata aagctagttg gtttgtaaat ataataagta aaaaatatcc
    14881 taaagaagct ttaaatgaag catttagtac tttagaaaaa gaattaaata taagtaaagc
    14941 taatacataa gctttgatta ttgattttat atactattgg ttttatacgc tatgacttga
    15001 cattatatta atcaaatagt atatttttaa atatagcaca atgaagtgtt aaaagagcaa
    15061 tggagctcca tagataaagt ctatggagct tttttgcgta tttaacttaa ggaggatagg
    15121 actttgaata actttgagat taaaactaga ataaaatttg gagaaggctc actaaaagct
    15181 ttgcaagaat taaaaaacaa aaatgtacta ataataacag acccttttat ggtgaaatca
    15241 aaaacaatag ataaaataac atctaattta ataaactcaa catatcaagt ttttgaagaa
    15301 atagtaccag acccaccaat agaagtagta gtagcaggaa tagaagcatt taaatctata
    15361 aatccagacg taataatagc attaggtggt ggttctgcaa tagatgcagc aaaatctata
    15421 atggactttt ctaaaaaaat attaaaaatt aacgaagtag agtttatagc aataccaaca
    15481 acaagtggaa caggttcaga agtaacatca tttgctgtaa taacagatag tcaaaaaaaa
    15541 tgtaagtatc cattagtgag tgatgattta cttccagata tggcaatact agacccagaa
    15601 cttgtaaaaa ctgtaccaaa ttttataaca gcagatacag ggatggatgt attgacacat
    15661 gctatagaag cttacgtatc tacaaattct aatgactttt cagatgcact agctgaaaaa
    15721 gctataaagt tagtatttaa atacttaata aaagcatata aagatggaaa tgacatagaa
    15781 gctagagaaa aaatgcacaa tgcatcttgt ttagcaggta tggcatttaa ccaagcatca
    15841 cttggcataa atcattctat tgcacatgta ttaggtggaa aattccatat accacatgga
    15901 agaacaaact ctatattact tcctcatgta atagaatata attcatcaat agtaggatat
    15961 actaacacaa cttactctgc tacagctaaa aaatatgcac aaatagcaga attagtagga
    16021 cttgggagtg ctaatataag aatatctgtt agaaatttag taaatgaaat aaagaaacta
    16081 caaaaagaaa tgaatatgcc aactaaattg acacaatgca aattaagttt agaagatata
    16141 actaatgaag aaagagaaat agcaaaactt gctataaaag atacttgtac attaactaat
    16201 cctaaggtac caactgaaga tgatataata aacatattaa agaacattaa ataactacat
    16261 tttattacat gtaaatataa tattatacaa atagggaaaa tgtttttaaa aatataaatt
    16321 atatattgac aaatataaaa cataaaacta taatgaaagt atcacaaagg cgtgatactt
    16381 tagtagaaag caatggagct tcttaggaat attaatatta ttcttatgga gctcctttta
    16441 ttttaatcaa atagcttttt aataaactat attcaaagaa agcagggaat aaatttgact
    16501 gaagaatcta agcaaagagt tattcaagaa tatgttcctg gaaaacaggt tacattagca
    16561 catatcatag ctaaccctaa tgaagatata tataagaagt taggattagt acttgataaa
    16621 aaagatgcaa taggaatact tacaataaca ccaagtgaag cgtcaataat agcagcagat
    16681 gttgctacaa aggcttcaaa tgtatcttta ggttttatag atagatttag tggttcagta
    16741 gtaatatcag gtgatgtaag ttctgtagaa tcagcgttaa atgatgtttt agaagtctta
    16801 ggaaatatgt taaacttctc atctacaaaa atcacaagga cataataata caatgaagaa
    16861 tataatattt atgggaaaga caggtagtgg taaaactacc ttatgtcaaa aactagacca
    16921 gttagaatta aagtataaaa aaactcaatc agtggaactt tataataatg caatagacac
    16981 tcctggtgag tatatggaaa atagaaacct atataatgcc ttaataacaa catcagcaga
    17041 tgctaaaatt atagcaatag tgtatgatgc cacacaagaa gaaaattata tagcaccagg
    17101 ttttgccagt atgttttgca aagacgtaat aggaattata actaaaataa ataaagctac
    17161 tgaaaacgaa gtcaatatag cttatgaaag actatcacta gcaggagcaa gtcaaatctt
    17221 taaaatagac acagttgata atattggact tgaaaaatta tttaaatatc tagaaaaata
    17281 taaaaatata gatgaagttt aaggggaaat atttttttat tcaaaaatat tattaaagta
    17341 tgataaaata aaaaaatgta taaactattt taagaagatt taatctttaa gcgaggtagg
    17401 aacatgggga aaaaaatact attggttgat gatgaaccac tgttaaggat ggatacaaaa
    17461 gatatattag aaagtcatgg ctatgaaata ataggcgaag caagtgatgg atttgaagct
    17521 gttgaaatgt gtaaaaaaca caaacctgat ttagttataa tggatataga gatgccaata
    17581 cttgatggta taaaggcagg caaaataata tgtaaagaaa atatagctgg tggagtactt
    17641 ttattaactt catttgaaga taaagaatac gtagaaaagg ctaaaagtat aggtgcttat
    17701 ggatatttag taaaaacagc aagtgaaaaa tcacttatcc caaccataga aatgtgttta
    17761 aataaggtaa atgaatttga aaaaatgaaa aaagatttag aaaaagtaaa ttctaaattg
    17821 aatgaaagaa aattagtaga aagagcaaaa ggtatactta taagagagtt taagatttct
    17881 gaggatgaag catacactag aataagaaaa ttaagtatgg ataaaagaac tacaatgatg
    17941 gaaattgcca aaatgattat aataggatac gatgactaat acgataaaaa aaatatcaac
    18001 tgcacaaaca tacttaaata ataacgaaat tgaaaaaatt atagaagtat caaaatcctt
    18061 agatttaatg gcttcttttt atgaagctga tgtttttata gatgtactaa gtaaatttga
    18121 tgatgaagca attgttgtgg cacatggtag acctaaagaa aagtcaatgt actgtgaaaa
    18181 tgttataggt aaaaaggctt taattgaaaa tgaaccagga gttataaagt gcttaaaaac
    18241 aggagaaaga gtaagagata ttaaagcttt aacacaggaa tataaactgg tcaaacaaaa
    18301 tattcagcca ataacactag atgacaaagt tttagcagta ctaatagttg aaaaagatat
    18361 aagtagtgaa gttaagaatg agtttaatgc tagtgaagac gaagaaaata aaaatttaca
    18421 tcagtttata aaacttattg gaaataatga ctttttagtt gataatttaa attcagccat
    18481 attaatattt gataaaaatg gaaaattaaa aattaaaaat cgtattgcaa ctgagatata
    18541 caaaaatctt gggtttggat atgatataca agatatgcat tacaatgatt tagatataga
    18601 aaccaacacc tttgaaaata tattaatgga tgaaaattat gatgagacaa atgaagtttc
    18661 aataggtaat atgtttttta aaataaagac catatacatc aaagatgatg aatttaaggt
    18721 ttgcaaaata gtacaagata taagtgattt aaagagaaaa gaagaagaat tagttttgaa
    18781 aacagtggct ataagagaag ctcatcatag agtaaaaaat aatcttcata cagtaatatc
    18841 tataataaaa aaacaaagta gattatctca aaatgatgaa gtaaagcagt gtttagataa
    18901 cataataaat agggtatttg caatactttc gactcattat ttactatcta aagaagttga
    18961 taataatata tctatacgag aaggtatcaa tttattagtg tcaaatattc aaggtggcta
    19021 tttatttagt aaggatatag atatacgtat aactggtgaa gattttaaaa ttagtggaga
    19081 aaaagcaaca gcaatacttt tggttataaa tgaaatacta caaaattgtt atgaccatgc
    19141 attttcggat agagaacatg gtactataca aatattaata aataaagata acgactatag
    19201 aaatattgct attatagatg atggaattgg atttgatagt aataatataa ataaaaatag
    19261 cttagggaca tatataatag atagttatat aacacagatg ttaaaaggaa atatagagag
    19321 aaaaagtagt gagaatggta cagaagtatt aattactata cctacacaaa ttaatattta
    19381 aataataact catctacaaa gtagtagttt taattgagca aagaggctta aggttattaa
    19441 tagattaagt taattgaatg tatttataaa aattataagt atatattcaa tttaacaggt
    19501 atttattata actttaagcc tctttgcttg tttaagacat acttaaattt taggaggtga
    19561 gaaaatgaga gaagagttat taagtgttgg tattgacatt ggaacaagta ctactcagtt
    19621 aattttttct aaattaatag tagaaaatac tgaatcaaat ttttcggtac ctagaataag
    19681 tatagtagac aaagaaatta tttataaaag caaagtttat ttcacccctc ttatttcaaa
    19741 taatgaaata aatggtcaac aaataaaaga tatagttgaa aatgaatata aaaaagcaaa
    19801 tatatctaaa gaagatatac atacaggagc agtaataata actggtgaaa cagctagaaa
    19861 agaaaatgca aatgatgtac ttcatacttt gagtggattt gctggggact tcgttgttgc
    19921 aacagcagga cctgatttag aaagtataat atcaggaaaa ggagctggag ctcatattta
    19981 ttcaaaagaa cattcaacta caattgtaaa tatagacata ggtgggggaa ctagtaacat
    20041 agcctcattt aaaaggggag aagtaaccga tactgggtgt ttggatatag gtggaaggct
    20101 tgtaaagata gataaaataa gtaaaaaaat aacttatata tcacctaaaa tagataaaat
    20161 cataaaagat aataatttaa atcttcaagt aggtacaatg gctactgtag aaaatacaaa
    20221 gccaatagtg gatataatgg ttgacttatt aatggaaagc ataggactaa agaaacagac
    20281 acctttgttt gattttataa taaccaataa atcaataagt atagatgaaa atattaaaaa
    20341 tgtttcattc tctggtggag tagctgatta tatttactat gatggagaaa taaaagatta
    20401 ttttgaatat ggtgacttgg gaattttact tgggcaagca ataaaaaatt gtgaatacct
    20461 taaaaaagta aatgtagtta aatctatgga aacaataaga gccacagtgg ttggagcagg
    20521 ttctcatact actgaagtaa gtggaagtac aataacttac actagcgaaa agtttccact
    20581 taagaacttg ccagttttaa aattatcaat tgatgaagaa acaggtactt caaaacaaat
    20641 cagtgaagct ataaaaaata aacttaattg gtttaaacta gaaaatgatt tacagaaagt
    20701 tgctatagcc atgataggaa agaaaaatcc aaccttttta gatatacaag agtatgctaa
    20761 agggtttgta gatggaatgc aacaaatcat agaaaatgat ttacctttta tagtaattgt
    20821 tgaaaatgat atggcaaaag tgttaggtca agcaatatat gcattattaa attatgaaaa
    20881 agaaattgtt tgtatagaca gtgtcaaggt tgaaaatgga gactatatcg acattggaaa
    20941 acctatagtt gaaggtaaag ttttacctgt ggtaataaaa acattagttt ttaattaata
    21001 gaaggaggta agtaaatgat tttaaataca aaattatttg gacgtactta tcagtttaaa
    21061 ggcttatatg atgtaatggc taaagctaat gaagaaaaat caggagataa attagcaggt
    21121 cttgcagcag aatcagctga agaaagaata gcagcaaaag ttgttttatc acacataaaa
    21181 ttggaggata taagaaataa tcctgcagtg gcatatgaag aagatgaagt aacaagaata
    21241 atacaagatg ctgtaaatga aaaagtttat gaagaaataa aaaattggac agtgtctgaa
    21301 cttagagaat ggctattgga ttcaaatact acaagtcttg atataagaag aatatcaaga
    21361 ggattaactt ctgaaatgat agcagcagtt gcaaaattaa tgtcaaatat ggacttagtt
    21421 tatgcagcta aaaagataaa ggttactgct cactgtaata caactatagg agaacaagga
    21481 acattatcag caagacttca acctaatcat ccaacagacg acccagatgg aatacttgca
    21541 tcacttcttg aaggtttaac ttttggtata ggagatgcag tacttggatt aaatccagtt
    21601 gatgactctg ttgagagtgt tactaaagta ttaaaaagat ttgaagaagt aaaacaaaaa
    21661 tatcaaatac caactcaaac atgtgtattg gcacacgtta ctacacaaat ggaagcaata
    21721 agaaatggtg ctcctgcaga tttaatattc caatctatag caggttctga aaaaggaaat
    21781 gaagcatttg gatttaatgg cgacactata gaagaagcta gacagttagc cttaaaacac
    21841 ggtacagcta caggacctaa cgttatgtat tttgaaactg gacaaggttc agaattatct
    21901 tcagaagcac atcatggaat agaccaagtt actatggaag ctagatgcta tggatttgct
    21961 aaaaagtatg aaccattctt agtaaataca gttgttgggt ttataggacc tgagtactta
    22021 tatgatgcta gagaagttgt aagagcagga cttgaagacc actttatggg taaactacat
    22081 ggcttaccaa tgggtgttga tgtttgttac actaaccata tgaaggctga ccaaaatgat
    22141 atggaaaact tagccatact attaacaaca gcaggatgta cgtattttat gggaatacct
    22201 catggagatg atgttatgct taactatcaa acaacaggat accatgaaac agcatcactt
    22261 agagaaatgt ttggactaac agcaataaaa gaatttgatg cttggatgga aaagatggga
    22321 ttctctaaag atggtaagtt aacagagttg gcgggagacg catctgtatt attaggatag
    22381 gaggtattta atatgaatga gaaggattta aaagcattgg tagaacaatt agttggacaa
    22441 atgcttggag aattagatac taatgttgtg tctgagactg ttaaaaaggc aactgaagtt
    22501 gtagtagaca acaatgcttg tatagatgat ataacagaag ttgatataag aaagcaatta
    22561 ctagtaaaaa atcctaagga tgcagaagct tatttagata tgaaagcaaa aacacctgca
    22621 agattaggta taggaagagc tggtactaga tataaaacag aaacagtttt aagatttaga
    22681 gcagaccatg ctgctgcaca agatgctgta ttctcttatg tagatgaaga atttataaaa
    22741 gaaaataata tgtttgcagt ggaaacttta tgtaaagata aagatgaata cttaacaaga
    22801 ccagatttgg gaagaaaatt ttctccagaa actataaata atataaaatc taaatttggt
    22861 acaaatcaaa aggttttaat attagttgga gatgggctta gctcagctgc aatagaggca
    22921 aatttaaaag actgtgtgcc agctataaaa cagggtctaa aaatgtatgg tatagattca
    22981 agtgaaattt tatttgttaa acattgtaga gttggtgcta tggaccactt aggtgaagaa
    23041 ttaggttgtg aagttatatg tatgttggtt ggagaaagac caggattagt tactgctgaa
    23101 tcaatgtcag catatatagc ttataagcca tatataggaa tggcagaagc aaaaagaaca
    23161 gttatatcaa acattcacaa aggtggaaca actgcagttg aagcaggtgc tcatatagct
    23221 gaacttataa aaactatgtt agataaaaaa gcttcaggaa tagaccttaa ataaagtcga
    23281 gggagtgtag aatatgaaaa atgatgtaat tcgtcctaat atactaggaa ttaaaataat
    23341 ttcaaatata agtccagaaa tggcacaaaa actagaatta aaatcacatc acaaaagctt
    23401 aggtttaata actgcagact gtgatgatgt tacgtataca gctcttgacg aagcaactaa
    23461 agcttcagaa gttgatgttg tatatgcaaa atcaatgtat gcaggtgctg caaatgcttc
    23521 aacaaaactt gctggtgaag tattaggaat aatagcaggt ccaagcccag cagaagtaag
    23581 aagtggtcta aatgcagtag ttgattttct agagtatgga gcaactttta taagtgcaaa
    23641 tgatgatgat tcaatagcat actatgctca ctgcgtatca agaacaggta catacctttc
    23701 agaggtagca ggaataagag aaggtgaagc attagcttat ttagtagcac caccacttga
    23761 agcaatgtat gcactagatg cagcaatgaa agctgcagat gttaagatgt gtgaattatt
    23821 tgcacctcca actgaaacaa actttggtgg agcattactt acaggttctc aatcggcttg
    23881 taaagcagca tgtgatgcat ttgcagaagc agtaaaatca gttgcagaca atccaacagg
    23941 attttaagga tagttagatg gatgctatag gcttaataga agtaatagga tatgttgctg
    24001 caatagaagc ttctgatgct tgtttaaaat ctgcaaatgt taatattgta agagttgata
    24061 aggttggggc aggtattgtt actttaacaa tatgtggaga tgtcggtgct gtaaaagctg
    24121 ctttagaagc gggtgaaata gcagcttcca gagttggtac attaagaaca tcacatatta
    24181 taccgagaat ccataatgaa gtaacaaatg ctttattcaa aactaaagaa cctaaagtct
    24241 gtgaagtttc agaagataaa gaaaaaaact ttgagattac attggaaata gctgataatg
    24301 tatcgaaaaa tttatcagaa aaagaaaatg taattttaga tgtcaatgaa aacagtggag
    24361 atactgaaaa tttatatagt gatatagata aaacaaacaa aaaaattgaa acagttgatg
    24421 atagtttaac agaagctaat gaggaaaaaa tagaaaacac taatgataaa gaagtattgg
    24481 aacaagttaa aatagaaaat tccgattttg atagagatga cctatcaaag aacagtgtaa
    24541 aaaaacttaa agctatggct aaaaaattag attcttcaat aacttataaa gacttaaatg
    24601 ttcttaaaaa agaagaatta ataaacttag ttaaaaagct tagcagaagg gatagatagt
    24661 tatgacactt ttagataaag atttagtatc tatacaagaa gtaagaactc ttgtaagaag
    24721 atctaaagtg gctcaagaga aactttctaa aatgagtcaa gagcaaatag ataaaatagt
    24781 aaaagctgtt gtagatgcag catttaataa tgctactaaa ttagctaaaa tggcaaatga
    24841 agaaactgga tttggaaaat gggaagataa agtaattaaa aatacttttg catctatggg
    24901 agtttatgaa actttaaaga acacaaaaac tattggaata attggtgaag ataaagaagc
    24961 caatacgata gatatagcta caccagttgg agttgttgca ggtcttatac cttcaacaaa
    25021 cccaacatca acagtaatat acaaaactat aatatctcta aaagcaggaa atactatagt
    25081 tttctctcca catccaaatg caaaaaactg catacttgaa acagttaata taataagtga
    25141 ggctgctata aaggctggag ctccagagga ttcaatatta tgtataacta atccaagtat
    25201 agttggaacc aatgaattga tgaaacataa agatacaaac ttaatactag caactggagg
    25261 agaagcaatg gttagagctg cttactcttc aggaacacca gctattggag ttggaccagg
    25321 aaatggacca gcatttatag ataaatcagc aaatgttaaa ttagcaatca aaagaataat
    25381 agattctaaa acttttgata atggtgttat atgtgcatca gaacaatcta tagtaataga
    25441 aaaatctatg gaagaaactg ttttaaaaga gcttaaaaat caaggtgcat atgttttaaa
    25501 tgaagaggaa agtgaaagat tagcaaaatt catattaaga gctaatggta ctatgaatcc
    25561 acaaatagtt ggtaaaagtg ttgaggtaat agcaaattta gcagacttaa caaatgtacc
    25621 taaaaataca aaagttctag ttgcaagaga aaataaagtt ggtcacaatg tagcctattc
    25681 aagagaaaaa cttacaccaa tactagcgtt ctatgttgaa gaaaatgtag aagctattat
    25741 gaacagatgc agagaaatat tgttaaatga aggtgcaggt catacattct caatgcatgt
    25801 aaatgatgaa gaattggtaa aaagatttgc ccttaatatg ccagtatcaa gaatacttgt
    25861 gaatactcct tcagcacttg gaggaatagg tgcatcaaca aaccttgtac cagcactaac
    25921 acttggttgt ggtgcaatag gtggaagttc aacttcaaac aatataggac cacttgattt
    25981 aataaatgtt aaaagagtag cttatggaat caaagaaata gaagaacttg gaagagataa
    26041 atctcaagtt gaaaaatcaa tgtttgactc aatggataaa gaagaattaa taaatcttct
    26101 tgttcaaaaa ctagtcaaag aactagcata actaaaataa acaatgaaac ttatggctat
    26161 cgctataaat ttctaaaaat ataaactata aaaaactata aaattaaatt tttggaggat
    26221 aagattatgg caagtgcaaa cgcattagga atgatagaaa ctaaaggatt agtaggagca
    26281 atagaagcag cagatgcaat ggttaaagct gcaaatgtac aattagtagg aaaagagcaa
    26341 gtaggtggag gattagttac tgtaatggta agaggagatg ttggagctgt taaagctgct
    26401 acagatgcag gagctacagc tgccgagaga gttggagaac taatatcagt tcatgttata
    26461 ccaagaccac actttgaagt agatgctata ttaccaaagg tatcagctga gtaatataag
    26521 aataattata aaatttaaat tttgattgaa aaagaggcta tctcaaaaat gagtcttact
    26581 aataaactca atgtattttg aggtagtctt ttttatacat ctaataggag atgtgataaa
    26641 atgggtgttt taacagaaaa cgaagtaaaa agaaaaattg gaaaaaacaa aaataatata
    26701 actgaatttt atatagaaaa aggtcaaata ataactcctt ctgcaaaatc ttatttagct
    26761 gagagaagta ttgagcttaa atatgttgat aaactttcag atgtaaacaa tgaacctaaa
    26821 gaagttgtaa aagaagtagt taaagagaaa aaatataaat atactactgt atttggcgcc
    26881 aaattggatg aaaaaccaga acatatgact caattaaatg gaaatctttt agtttttaaa
    26941 gaccataaaa gaataatatt gagaggaaaa atagattctc ttgaatcaga aatactaaag
    27001 gtacagatac tttgtcagaa actagatatg ccaaagcttg ttaaggaatt gcaagaagta
    27061 ttagactttg taagaaatat aatgagatgt gaagttttag atgaaaagct aggggacttt
    27121 aaacttttag gattaactcc tcaagaactt agagaacaat ctcactatcc taaaaaatac
    27181 tttggtatag gacatgagtt cccaagttat gaaatgggag aagtagtagt agctataaat
    27241 agtataagaa gtaatacacg agaggttgaa cttgcagcct atgaagcatt taagggtgag
    27301 tatggaaatg ttcacagaga agatttaata aaggcactta atagattatc gtcagtattt
    27361 tggataatga tatataaggt tagaactaat aagtataagt agttggagga cataatggag
    27421 aatctattaa atgaaatagt ggaagaagta ataactagag ttaaaaaaga agcatttata
    27481 gaagttgaag catcaggaag acacgttcac ttaagtagag aagatgtcga taaattattt
    27541 ggagaaggat atactcttac aaaactaaaa gacctatctc aaccaggtca atatgcatgt
    27601 aaggaaagag ttacaataac tggtcctaaa ggaagtataa aaaatgtagt tgtacttgga
    27661 ccatgtagaa atgaaactca ggtagaaata tctttaacag atggttcaac tcttggacta
    27721 aaagctccta taaaacaaag tggagactta gaaggtactt taagtattaa aatatcaaca
    27781 caatatggtg aagttgaact tgataagggg ctaatggttg ctaaaagaca tatacacatg
    27841 actcctaaag atgctgaaaa attcaatgta tgtgataaag agatagttga agctaaggtg
    27901 atgggtcaaa gacctttaac atttgatgat gtagtaataa gagtgagtga cagttttaaa
    27961 acttatatgc atatagacta tgatgaagcc aatgcatgtg gttattcaaa aggaactgtt
    28021 gctaaaataa taaagaaagc ataaatttaa cctactatat aaattacctc tagggaggat
    28081 ttaatatgaa ttatgataac cttgtagatt taataacgga agaaatctat aaaaaaataa
    28141 atagtaatga aataaaaata tctaataaac ctaaagctgt gattgtattt gaacaagata
    28201 acaataaatt taacttatta aaagatggat ttgaaatagt agaatttgat aaaagtataa
    28261 gggaatgtga aatagtgata gtttcaagac tttgtatgag ggggctatcg aatatagcac
    28321 ttggaaattc aacaagtgat gaagaaagat ttatactaaa aatgattatg aatggcaaaa
    28381 aagtatatgt cctagatgaa ggaattgaat acaaaaaata taaggatact gcaccaaaag
    28441 cactatataa gaaatttatg tcatttgaag atgaaatatg taaatttggt gtagaaatta
    28501 taaaagactt aaatgttata actaaaaata agttaaatat aaagaaagaa ctagaaagta
    28561 ctagaggttc taaaaaagaa gatacaaaag ttttagataa agatatttta aatttaacca
    28621 gtgtagaaag tgtaaaaata gataatgaat ttagtttgga tttaaggaat aaaaaactta
    28681 tatcggaagc tgacttaaga aaaccaacta taaatggagt taaaaacata ttagttaata
    28741 aaaaaagtat aataacacca ttagctgtag attttatgag aatacaccat ctcaaactaa
    28801 agaaactgta aggaggtaat tttatggata taggaaaagt tgtaggtaat gtttgggcta
    28861 caagaaaaga tgaaaaatta tgtggccaaa aacttttagt tgtaaaaatt ttaaaaacta
    28921 aagacacata caaggaaggc ttcatggttg cagccgataa tgcaggagca ggaaatggag
    28981 acttagttct tatatccaaa ggttcctcag ctagagagtc gattgaaaaa tctcatgttc
    29041 cagtagatgc aactatagtt ggagtagtcg attcgtttga ggtgtttgat gaataaaagt
    29101 ataggagcta tagagtttaa aagcattgct aaaggtatag aagtatccaa tgaaatgata
    29161 aagaaatctt cagttgatgt attgtactta aaaagtattt gcccaggtaa atttctaata
    29221 atagtaggtg gagaaacttc ttatataaat gaatgtgtag attatggaat aaaacttgga
    29281 gaaggatata ttgtagataa cttcgtaata aatgcaattt cacaagaaat attagatgga
    29341 tttaaaaata agtatcaaaa gctagatagt atagtctcta taggcgttgt tgaaagtagt
    29401 aaaatatgcg ctggaataaa aatgcttgat aagactttaa aatctggcga cttagtatta
    29461 gtaaaacttc aattatcttt tgctataggt ggcaaattag tatatatagt agcaggagat
    29521 ttaagtagtt tagaatatgc attaaaagaa agtgaaaatg tagtaagaga aaaagaagta
    29581 atatataaga ctgtaatacc atcagtagac agtcaaataa taaaaagtct aataaaataa
    29641 tggggggaat tatgagtata aacgaaatta taatctatgt aatggtagtc ttcatggtac
    29701 ttggagctat agataaatgt ataggtaaca aatttggtct tggagaacaa tttgaggaag
    29761 gtataatggc aatggggtca cttgcagttg caatggttgg tgttatatgt ttagcaccag
    29821 ttcttgctga tgtattaaga ccaattgtag taccagtatt taatatactt ggagctgacc
    29881 cagctatgtt tgctggaagt ttattagcta atgatatggg tggtgcgcca cttgcacttg
    29941 aacttgcgaa agaccctaat gctgggttat ttggtggatt aatagtaggg gctatgatgg
    30001 gacctacaat agtatttata ataccagttg cgcttggaat aattgaaaaa gaagaccaaa
    30061 aattcttagc aacaggaata cttgcaggta taataacaat acctattgga gcattcgttg
    30121 gtggattagt tgcaggattc gaggtaatga tggttcttag aaacttagtg ccaataataa
    30181 tatttgcagt agttatagca cttggattat taaaattcga aaatgctatg ataaaaggat
    30241 tcacatactt tggaaaaggt gtagtaatag ttataacttt aggacttgct gctgccatag
    30301 ttgaagcttt aacaggaata gttgtaatac ctggaatgaa accaatcagt gaaggtatag
    30361 aaatagttgg agatatagca atagttttag caggagcatt cccattagtg tttgttataa
    30421 caaaggtatt taataaacca ttaatggctt taggaaaagt tcttggaatg aatgatgtat
    30481 cagcagcagg ccttgttgca agtttagcta actgtatacc aatgtttggt atgatgaaag
    30541 atatggacaa tagaggaaaa ataataaatg tagcattctc tgtatcagca gcattcgtat
    30601 ttggagacca cttaggattt acggcaggat ttaattctaa tatgataaca ccaatgatag
    30661 ttgctaaatt agttggtggt ataacagcag tattgttagc tatggttatc gcaaataaga
    30721 cactaaagaa ggagaatgta taagatggat atatcaaata tagataaaaa tttaattgaa
    30781 acattagtaa gacaaataat agaagaaaaa ataagtggaa ctaaagacac agtagatttt
    30841 gttagaaata aagacattag tggaataact tctataaagt taccaactgt aaaagttagt
    30901 gaatctgata gattagatac agggaatcca agtgatgtag tttacacaaa agatttattt
    30961 acattagagg aaagcccaag attaggttgt ggtatgatgg aaatgaaaga aacaactttt
    31021 gattggactc taaattatga tgaaatagat tatgtaatag atggaacttt agatataata
    31081 atagatggaa gaaaggtttc tgcttcttca ggtgaattaa tattcatacc aaaaggaagt
    31141 aagatacaat tttctgtacc tgattatgct agatttatat atgtaacata tccggcagat
    31201 tgggcatctc aaaattaata aaaatcaagt taagttaata atcaaataaa taatttaaaa
    31261 tacaaactct taaataagca cgcatattta aaaaagctat gaattaaaat tcatagcttt
    31321 ttttataaag aatgttatat tttagacgta ttttttctat atttactggg agatatatta
    31381 tattttttat taaataatct aataaaatgc tctacatttg gataaccaat actattttac
    31441 tgataatctt ttccttatca ctaatcttac attttaaaat attattttta ctcgtaatat
    31501 tatcataaga atttgtttct tatttaaaac taattagaat tataaagttt attgccatgt
    31561 tattaataaa ataaatccag ttaaatcgag tgctagttaa agtaataaga aacttttaca
    31621 atggtttcct ttatcgattg aaataaaagt taatatggta taatatctaa agagagaatc
    31681 ttatcaatta gaatatgcat agaaacaagt ggcttaaaag gagacgttat atggaagaga
    31741 tagtaaagaa ggaacaagca agtatgaatg atattttttt gtatcttaaa gctaaatcaa
    31801 actcattata taaatttgta atattatata atgagtttat caataaacct aaagattatg
    31861 gaactgggga acttataaac atggttgaag tacatatgct aacagcgatt gaagaaaatc
    31921 caggaataag tccaactcag ttagctaaaa tatggaacag aactaaaggt gcaatatctc
    31981 aaactatatc taaattggag aaaaagggtt atataactaa agaaaagaaa gaaggaaatg
    32041 caaaaactat attactatat ccaaccacat caggagtaga gttaagtaag gcacataaac
    32101 tatatgacac catagatgtt acaagaacat ttgaatactt aatcaaggag tgtacattag
    32161 aggagataga tagtttttat aaagtaattg atttgtttat taatttatta gaagaatctc
    32221 cgcaggaaaa taatgattct gaaaaagtgt agctgagatt gaagttgaat aaagagaaat
    32281 agatattata gaagtagtac ttaagtacac attatataaa aatataatag gtataggatt
    32341 aaaaagttta gtggtttaaa gtttaaccac taaacttttt taatgtctat aatctactat
    32401 tatttaattt actaaaaata aaaaaactca ttatattaag atagaaatag aaaaataact
    32461 agaaaaatac tataatatat cagcttaata cagaaaaaag ttaaaaaatt tgagaaaaat
    32521 aaaaatgaaa acgttttata ttgacataga gaaaaagtag tgataccatt taaatatagt
    32581 ttagtagcta aactatattt aaattataat aactatttta gggggatgtt atgaatttaa
    32641 aacaattaag tgaaaaatac gaagaatatg taattcaaat gagaagagaa tttcataagt
    32701 atccagaatt atcttttaaa gaaataagaa caacccaaag aataagggaa gaattacaaa
    32761 aaataggggt cccttttgta tctattgaac caaatatcgt aatagctact atacaaggca
    32821 aaaatgaagg taagacaatt gcaattagag gagatataga tgcgcttcca atgcaagaag
    32881 attcagatgt tgaatacaaa tcagaatatg atggaataat gcattcttgt ggacatgatg
    32941 ctcatggagc tatgttacta ggacttgcac atatgctaaa tgatataaga aaagatttaa
    33001 aaggtagagt attattagtt tttcaagcag ctgaagaagt tggtggtgga cacaaggaga
    33061 taatacagta ctttaaggaa aatggaggac cggatagatt aatagctact catgtttggt
    33121 ccgatattga agctggtaaa atttctgttg aaccaggacc tcgtatggct ggtgggtctg
    33181 gttggagaat agacataaca ggtagaggag gtcatggttc tagaccagat caaagcatag
    33241 atcctataaa gccagcttgt gatatagttt taaaagtatc ttctatacca gttaatcata
    33301 taagtgtact agaacaatgt gttgtacatg catgtgcaat acatggagga actacaatag
    33361 gaaatgttat tccaaacaat gcagaggtaa taggtggata tagatatttt actgaagaat
    33421 caggcaaaaa agtgtttgac attataaagc aaatgagtaa tggtgttgga caagtttatg
    33481 gagtggatgt gaaggttact catactggag gcataggacc tgttatcaat gatgaagaag
    33541 cagttaagat ggctaaagaa atagtttcta atatagatgg attggagtta gattcttatg
    33601 agccaatatg tgcatcagat tgttatggtg aaatattaaa agagtattct ggcttttatt
    33661 gttatctagg ggtaggtaac aaagaaaaag gaataatata tgcacaacac catcctaagt
    33721 acaatataga tgaagatata ttaaagttag gttgcgaatt tatggctaaa tatgcagttg
    33781 aatttttaaa taaaaataat aactaaaata aatctaattt tataaatggg gggatgaaaa
    33841 tgcaaggtgc attaaaggaa aataagaaaa aaagtggtgg aggattttta ggatggattg
    33901 aaaaagttgg gaataaaatg ccacatcctc tagcattatt tacatatatt acactgatag
    33961 tagtagcatt atctgcaata gcaagctttt taggtttttc agcaacaagt cctgctacag
    34021 gaaagttaat aaaagttatg aacttaataa gtgcaaaagg tttagtacta tttatgcaag
    34081 agtttgttaa gaacttccaa aacttccctg tgcttggagt agttttagtt atggcagttg
    34141 ccacaggagt ttgtgaaaag acaggatttt tttcaactgc cataaaaatg agtttatcaa
    34201 aagttaaggg gaatgcggtt gtatttataa tagcttttat aggagtattt gctaatcaag
    34261 ctggtgatgc tgcttttgta ttagtaccaa ctcttgcagg agcaatattt tatggattaa
    34321 atagaaatcc attagctggt atattctgtg gatttgcatc agttggtggt ggatttgcaa
    34381 cagctgtaat tcctggggga tgggacgtta cgctaacgcc aataactgta tcagctgctc
    34441 aaactattca acctgcattt gatatgacat tattagctag ttattatgca ctatttgtat
    34501 ctgcgtttat agtagctaca gtatcaacaa tagtaacggt taaatttata gaacctaaat
    34561 taggtaagta tactggtaaa ccagaaggta tagatgataa tcaaggtttt gaggtcacaa
    34621 aagaacaagc aaaagcagca aagttagcag gttttacagt tttagcttat gtagcgttat
    34681 taattgcttt gtgtatacca gctaatagtt ttttaagaag tccagaaggt tctttaatat
    34741 ttggagcacc acttatgtct tgcttacagt tttttatagt aatactattc ttcttgccag
    34801 ggattgtgta tggaatgagg gttggtaaaa tcaagactgt aaaagactta aatgatatat
    34861 tatgtcaatc aatggcagca atggcaccgt ttatcgtact tgcaatagtt ataggtcaat
    34921 tcttaacgct attctcagtg tctaatttag cacaggtact agctataaaa ggtggagcat
    34981 tactcaactc attgccacta ccaccacaag ctataatact gctattctta gtactagtag
    35041 cgtttataaa tatatttgtt ataagcggaa gtacaaaatg gatgatattt ggaccagtat
    35101 ttgttccaat gttaatgcaa ttaaacatac atccagcatt tactcagttt gtatatagat
    35161 taggagattc tgtaaccaat catttatcac cattaaatgc attctttata atacttttag
    35221 caacagtcca aaaatacgat aaaaatgcag gtatgggaac tatattctca gctatgatac
    35281 cttacactat aggttacttt gtagtacttg cagttttagt agtagtttgg atgacaatag
    35341 gtataccagt aggaataggt ggacaagttt ggttataaaa catatttaat aattttggga
    35401 ggaaaaaaaa tggaaacaac tgaaataaga tacaattttg atgaagtaat agatagaagt
    35461 ggaacaaact gtcttaaata tgatcttaag agtcaattta tgccagaatc tccagaagat
    35521 gcactaccac tatgggtagc agatatggat tttgcatgtg cccctgagat aattaatgca
    35581 atgcatgaaa gaatagacag aaaaatattt ggatatagct ctcaacaaac tgatgattat
    35641 tatgaagctg tatgtggatg gtttaagaga agatttgatt ggaaaataga aaaagagaat
    35701 atattcttta gcccaggggt tgtgcctgcg ttaggatttt tcacacaaat attaacacaa
    35761 aagggtgatg gtatcataat agaaaagcct gtatactatc cttttgaaga taaaataact
    35821 aacaatgaaa gaaaagtagt taatagtcct ttaaagtttg aagatggtca ttattctatg
    35881 gattatgatg gatttgaaga attagctaaa gatgaaaata ataaggtgtt tatattatgt
    35941 agtcctcata atccagttgg tagagtatgg aaaaaagaag agcttagaaa aatagtagac
    36001 atatgtaaga aatatgattt gtggataata tctgatgaaa tacattgtga tattattcgt
    36061 aaaggtgaaa agcatatacc attagaagta gcatgtcctg attataaaga tagaataata
    36121 acttgtacag ctccaagtaa gagttttaac ttagctggta tgcaattatc aaatatagta
    36181 atcaataata aggaattaca agaaaaatgg atgcttgaaa cagattctaa attagctata
    36241 ttcctaccta atccattcgc aatagttgct actaaagttg cttataatga ttgtgaagat
    36301 tggatgaatc aagtaaatga gtatatagat ggtaatatta aatatgtaga agattttgtt
    36361 aatgagtata tgcctaaagt aaagataata aaatctcaag gaacttactt agtttggtta
    36421 gactttagag ggtatggatt agatgcaaaa cagcttgaat atgtaatgct taacaaggcg
    36481 aaggtattgc tagatgaagg atacatattc ggagaagaag gagcaggatt tgaaagaata
    36541 aatgttgctt cacctagaac aattatagaa gagtgtatga atagaataaa atgtgcattt
    36601 gaaggattat aatagtaata tctaaataat atatttgtgt attttaaaaa aagactatgc
    36661 taaaaaaata tttcaaagca tagtctttta aagttttatg atgagtttaa aaaatttcaa
    36721 aacgttacta ttcacttata tgtttatatt agaaataatt ccacaatata ctcattttct
    36781 aaagttgcac ttttatacac cttgcttcac caatatcatg tgtaaccaaa atagtagact
    36841 tattctcatt cttaataata ctataaacat catcacaaac taataatcta gtctgataat
    36901 caagagctga aaaaggttca tctaaaagta gaatatctgg atttacagaa agtgttctaa
    36961 taagcgcaac tctttgtctc atacctccag ataattcttt tggatacata cttctaaaat
    37021 cccataatcc ataagtcttt aaaaggcttt caactctatc taaagatttt ttatcttttt
    37081 tgccttgaat ttccaatcca atagttatat tatccattat atttctccat tcaagcaaat
    37141 tatctttttg aaacatatat ccaatatttc cagtaatctt tatatcacca ctagttggtt
    37201 ttaaaagatt agtaagaata tttaatattg tagatttacc acttccagaa ggaccaagca
    37261 aagttaatat ttctccttct ttcaagttaa aattgacatc ctttaatact tcaagctcgc
    37321 cttccttagt gtagaagttc atatttatat ttttaacttc tactatgttg tcattcatta
    37381 tgccaccccc tataactttt agctcgtata tattatgtta ttaacaatat gacctatttg
    37441 taccattttt cataaatata atataaatat tttgtttatt tacgtatttt cttagtaact
    37501 tgtacgtata aattatagat aaataaatta taaggtaggg gataaatttg agtaacataa
    37561 taacgaattt aatagagtca atatttacta atccaataac tatattgttt ttacttgcaa
    37621 taactgtgta ttctgttttt aaaataatag aaaataacag agtatattca tttgtaagtt
    37681 caaaattaga cgaaatcaat agagactata agacaagtga gttttataaa aaggtaaggg
    37741 atgactacta tacatatagt aaagaaaatc cttatgcaga cgtaaatata acttcattta
    37801 tagaggaagt tgtatctgat ttaaagcata ataatttgcc attgttagaa aaaattagaa
    37861 gtataaaaaa ttcatcttca ataagtatat tacttggggt tttaggtacg tttgttggtc
    37921 tttctacaat gcttttatgt gttgatacta aagacattat aaattcactt ccttcaacta
    37981 ttagtagtat gcaaactgca tttacaacta gtatatttgg agttgtattt tctctaatta
    38041 taggttattt tactaagata aaagattgtg aacatgtttt gatacaaata atgttaaaat
    38101 ctgaaaattt actaacatct gaaataactc attttaagtc agaaagaatg gatttaaaag
    38161 tagaagaggt aaaaaataca ataaaacaaa taagtaagtc tatagaagct attgaaaaat
    38221 ttgataaaat atctaaagat ttaaatgact ttaatgatga atttatcagt ggtatagaag
    38281 ctttaaaaag ccttttagaa ggttctcaaa gttctattaa gacatttgac cagagcgtaa
    38341 gaaaattaga taaacagttt aatattttaa atataaaatt tgtaaagctt tttgataaat
    38401 atgataatca agataatata aataaagaga ttttatttga tataaaagaa tcttcaaaaa
    38461 atatatacaa tgccactgaa agccaattca aaattagaga ttatataaaa aatataaatg
    38521 caggatttgc tctatatgaa agaagtgctc aagatttatt aactaaatta atgacccatg
    38581 aaaataaaat ctctcaaaat caaaaaatcc ttttagatga aaagtttacc ttagatgact
    38641 caataaaaaa tctctcaagt attattgaaa acttttctaa tgacctacaa gttaaactgg
    38701 atatgatgtt tgaaaattct ttagatattc aagataagtt agatgttatg tttaataact
    38761 cttttatgaa tgatgaagtt cctcttgata gtgaagaatt atttaaggat gatgttaata
    38821 atgtatttaa tccttttagt gaagaaattt atgagataga ggataaagaa ataaaggtca
    38881 taggtgagga tgagttaaat gaataataaa tatagaagaa ctgttaacag agaatttgaa
    38941 aagagtagct tttggccaac atttacagat ttattatcta ctgtattgat ggttgtaatt
    39001 cttatcttat ttagctcaga aagtatttca ggttctgttg aacaagattt agctaagaat
    39061 gtcaatgctt ctgttgaaga aacttttaaa aaaagtggaa tacctgtgaa ggtagataaa
    39121 tctaatgggc aagtaacttt tggtgaaaaa accatgtttg atgtagatag tgatgtttta
    39181 aaaccagagg ctaaagaaat gctaaaaatg tttgttccaa agtacataga gactatttat
    39241 aaagattatg gtgactatat atccaaaata gttatagaag gtcatacaga tgatgtggga
    39301 agttatatat acaacttaga tttatcgcaa agaagagcat atagcgttgc taaatttata
    39361 gtgggagatg aaataggtga ctataaatac aaagataaag tgactaagca tattattgca
    39421 ataggaaggt caaaagctga actcatcaaa aatggtgaca atagcgtgaa tagagatgca
    39481 tctagaagag tagaactaaa atacgaaata aatattaatc aaaataaata attaaatttt
    39541 tataaaaaaa aagaaggcag ttggtgtgag ctttaagcct tctttaagga aaaagtttat
    39601 ttatttttgt tgatacttaa catattatag tttttagaag cagtttgcaa tatattaaac
    39661 gtaaatggtc gtttaaaatg cataactgga tactactgat gtaaaatatt tcattttata
    39721 taatataaaa attatacagt atcaattttc tatattattg tactataatc tattatttaa
    39781 aatattatgt aaaaaaatat cataaaaacg catatcatgt tataattact agagtattat
    39841 gaatatggag gcgtagtttg tgatagaaat aagtataaaa aataaaaaaa attctaaaat
    39901 taaaactttg atacttttat tgatagtatc tatatcaatt tatttaactg gttgtactac
    39961 attagataat ggaaataatc aatcaaataa taatgattct ttgtctagta gtatatcaag
    40021 tgataagaat gtaaaaattc attttattga cactggaaat agtgatgcaa tattgattca
    40081 agatggtaaa acttttatat tgatagatgg gggagataat gatgatgagg gattaatggt
    40141 agattaccta aacaatcaag gtgtaaaaga tattaaatat cttatagcta cccattctca
    40201 tgcagaccat ttaggtggac ttgattctgt tgtcaaaaac tttaatatag aaaatgtttt
    40261 tgtatcgaat ggttcagcag aaacaaagag ttatagggac tttataaatg ctttagcaaa
    40321 taagggttta tccccaagtg taccgcttga aaataataag ttctatttag aagattctta
    40381 ttttgaagtt ctaaatacaa atgggggaga tactactaat gaacaatctc tagtccttgt
    40441 atatactaat gggaatgata aagttttatt tacaggtgat gctgaagaag gtaccgaaaa
    40501 agaaatactc cctaagcttg agaaagtaga ccttttaaaa gtagctcatc atggttctcg
    40561 tagtagttca tctcaagagt ttttagataa agtaaatcct gaatatgcgg ttcttttagt
    40621 aggcaagggt aattcatatg gtcatccaca tcaggagaca atgaataaat taaaaaaaat
    40681 gggagtaaaa gtacatagaa gtgatgagtg ttcagatata atatttgaat caacaggtga
    40741 tggagtattt acaagttgta aagatggaag ttataataaa ggcgttagag aagatggaaa
    40801 ctctggaaaa tcaaacagta atacaagtaa aaatgattct tttaaaaata aacaaaatac
    40861 atccaattca gaagaaatag tgtattttac tccaaaaggt aagagttatc actctacaaa
    40921 aaattgtagt gggctttcaa gaagtaaaaa aatattatca ggcacaattg cagaaagtaa
    40981 gaaaaatgac ccatgtgata tatgttatgg aaaataacaa aaaaacaacc aatttatcta
    41041 taaagcttct gaactttaaa tcatttaaaa aataaaataa atgcataaaa aaataagcta
    41101 taatcaatag ataacacatt ttatctatac gaatagctta tttttttaag tattttttaa
    41161 tagctattta ataactctaa atacaccagt tacaatacct acaatttcaa cttctgagtc
    41221 attgagcata attggttcca taaaatcatt ttctggctga agtcttatta aatttccttc
    41281 tttaaaaaac ctcttaactg tagcagattc accatttata agtgcaacta ctatctgaga
    41341 atttaaggct gtattttttt tgtctactac aacgtaatct tcatctaaaa ttcctgcatt
    41401 aatcatactt tcgcctttta ctcttaatac aaaattgtta ctgcccttta ctaaactggc
    41461 agggaatgga atgtattcct ctatgttttg ttgagctaaa atgggttctc cagctgttat
    41521 ttgacctact aaaggaagct ctattatttc ttgattagct ccagaaacat catttacttt
    41581 actacgttct aaaacttcaa tagctcttgg tttagtaggg tcctttctta tgtatcccag
    41641 tttttcaagt ttatttagat gagagtgcac agttgaagta gatcttaacc ctacagcagt
    41701 acatatttct cttacagcag gtggataacc ttttaatatg atttgagact ttataaattc
    41761 caatatcaag acttgctttt cagttagatc taaatacata acatcactca tttccaaaca
    41821 tattttgttt ttatttccat acactttata tttttaatta taacataatc catttatatc
    41881 tgcaaacatt tgttcctgat ttttaatcgt cctcaatcca ttcaaaattc ttgactatat
    41941 cacgttttac atttttctta tgagctgcat aaagctgagt agttgtgaca ttatcatggt
    42001 caagtaagtt ttgaacatca tatatagaaa atcctgtttg gattagagaa gttgcagccg
    42061 ttgctcttaa tttatgggga ctatatccat tgtctctagt agtatcaagt ggaatagatg
    42121 tatatttttt taccagtgtt cttatagcct ttgctgtaat tctcttattt tgaagagaca
    42181 aaaataaagc atctttttct tcatcattta atagttcatc tcttgttctt tcgttttgca
    42241 aataatcttt tattacatgt tcacaagtat gatttatagg cattaaaact tctttcccac
    42301 gttttctata tattttaaat tcacctcttg aaaaattaaa agaggagata ttgagttctc
    42361 taagctcatt taatctaagc ccgtatgtaa caaataatgc tagtatagct ttgtcacgta
    42421 atttagtttt tctccaatat accttttctt tctctgtaag cccttcacct gtttctactg
    42481 attcaagcat cttagcaact tcatctatct caaggcgctt aatagcatct ggctgaggtt
    42541 taggaagttt tattggattg aatccatcag ttatattatt atctatctga gagtttctgt
    42601 ataagaattt aaatagagta gagatggatg atttttttct tgctaaagct ctattgttat
    42661 tttcaaaaat caatgtgttt ttttctgtat ttttgtaata tctactgcaa taatcaccta
    42721 agaataaatt tatatctctt gattttattg tattaaaatc atcttctgta atatctttta
    42781 cacaatctgc atttgttaat tctttggttt caatcaaata tgaacaaaaa aaattaatat
    42841 cttctaaata agcaagtcgt gtagaaactg caacagaacc ttttaaatat ataaaataat
    42901 ccttcataaa tacaggaagt ttattttcca aaagtagaca tttttctatg agttcatttt
    42961 ctttgataac aatattatca ggtttatctg atttattatg tacttttata attttcttat
    43021 cattattcaa aattaaacct cctaaaacta aaatataaat cttttatatt attttttgat
    43081 atttatacca agtgagtata aatatttaat ttaatcattt tttacatttt taagagatta
    43141 gcagtgcttt agatgaaatt atcactaact attccctaaa tccacattta aagactagtt
    43201 gaatttaagt actctttttt atttctcaat atatttatag aaatatttta aaatatattg
    43261 agaaattttt tatgctctac taaaatcttt tttatataat atttttatat gtttctaacg
    43321 aaaccaaata ttagtaaaat atgtatttat ttaactaaag tttttaaatg ggctgactaa
    43381 gcttaaaata taggatatta tgagagttac tattgaaaaa ataaacccta ttgccataaa
    43441 gaaacttata aatatgttat acttaactat taaactggat atattcaagt tatcaaatcc
    43501 aaataagtat gtaattgaac ttattacaaa aataactata actataaagc tcagaccatt
    43561 taagctattt tttaaatcag cactactaag tgacatatgt gtagatatag aatacattaa
    43621 aaacataaat ataaaatact tcaatgaata tacactaggt gttaacaaca ttattcttat
    43681 aaaattggaa atatcaccta aaataatgtg tataaaccca tttatattta aattattaat
    43741 catacttaca tataacttta aatctatatt ttgagtcact ttcatataac tatctggcag
    43801 taatatctta aaaattaaaa taatcattat tgttccacct ataataggtg caattcctat
    43861 aaagaaattt cctatacttt gataaagatt atctttttta tagctatgac ttacatatcc
    43921 tagtatacca tcatttttac tttctattgg tctgaaaaac ttaactgaat ttattttatg
    43981 catgaaaatt aaacacatta tcaaatgact caattcatga acaaacgttc ctatagctcc
    44041 agttacaata attccagttt ttccaaaaga tgaaaatata aatttattat ttagattttc
    44101 tgtaatgcta aaaatcaatc caaatacaat aaatattcct atgaaacaaa aaatatttat
    44161 tacacttatt tttaaaattt cgattatata aatcataagt taagtcctca tgtaaaagta
    44221 tttaactact ctacttcata tccattacag cttaaaattt tacaagcatt ttctatatct
    44281 ttttctttta ctaagatata gtctgtatca taagtagaaa ttgcaaatat gcttattttg
    44341 ttgtctgcta acaaactact taacttagat aaaattccta caagtgaaaa gtctaaagga
    44401 cctagtatct taagtattct ccactccttt tctgacttga catcagaagg aatattatta
    44461 tttaaacata caacacttaa ttcatcatca gttctagtta tagagtaaaa cttctctgta
    44521 tctatccatg ttggtatttt actgtcatta tttaatctac atactgcata ctcttctacc
    44581 aataatttta atttcataat gtatatttcc tccaatctta tttgtttact taagattata
    44641 cattaaaagt tacataaaat aaaacatata aagtaaaaaa ggttcactat agtgtcctat
    44701 ttctatagcc aacctttaaa acttaattaa attctaataa agagatatat tatctaggtt
    44761 caattataag tttaatggct gttttcttat caccttcgat ttctatatca gtaaatgcgg
    44821 gaatgcaaac taaatccatt ccactaggtg caacaaaacc tcttgctatt gcaattgatt
    44881 ttatcgcttg atttagagct ccagctccta tagcttgtat ttctgcaacg cctcgttctc
    44941 ttagtactcc agccaaggct ccagctacag aattaggatt agattttgat gaaactttta
    45001 gtacctccat ttcaacatct ccttgttaat ttgttaaagt atccattacc taaagtacta
    45061 aatcataatt gccatttact aattacaatc atcatttaaa gtatactttt ataaaaatat
    45121 acttctataa tcgttttaag aaaaccttta ttttttttaa ccattttatt atgaaaaaac
    45181 tacaaatttc tttatattct ataagcattt tccaatattt ctaaattttt tatatctttg
    45241 agctataatt tcctctttat ccatatcttt gtaatgattt aatctttcta aaatataagc
    45301 ttttatttct tttgaaacag cttctacatc tttttgtgct cctccaagag gttcttttat
    45361 aatcttatct attattttta aatcatataa atcattactt gtaagcttca taacatcaca
    45421 agcttcttta gctttagatg aatctttaaa tagaatacta gaaagtcctt ctggagaaat
    45481 tacagaataa actgaatgtt ctaacataca tacatcattt cctactccga tacctaaagc
    45541 tcctccacta ccaccttcac caattacaaa agtgattact ggaacagaaa gtttactcat
    45601 ttcaagtaag tttcttgcaa tagcttctcc ttgtcctctt tcttctgctt ctagaccaca
    45661 aaaagctcct gatgtatcaa taaacgttat tataggtcta ttaaattttt cagcttgttt
    45721 cataagtctt aatgcttttc tgtatccttc tggatgaggc attccaaaat ttctttttat
    45781 attttctttt gtatctcttc ctttttggtg tccaactata gtaacattaa actttcctat
    45841 ctgaccaatt cctccaacca tagaagggtc atctttaaaa agcctatctc catgaagttc
    45901 taaaaaatta gaacaaatat gttctatgta ttccaatgtc gtaggtctct ttatatctct
    45961 acttaatgtt accttttcat atgctgatag atgtgaaaaa gcatcttcct taagcttttc
    46021 caatttctca ttaagtgaat ttattttatc acttaaatct atattatttg ccttagaaat
    46081 agttattaat tgtttaatat cattttctaa gacttttatt ttttcactat tattttcaat
    46141 caaaacagtt cctcctttat gccctatttc ttgtgcatag caagaatttg atataatact
    46201 tccttcattt ttcttctatc tactatcatg tcaataaaac ctttttcaag taaaaactca
    46261 gaagtttgaa atccttcagg aagtttttga tttattgttt gctctattac tcttggacct
    46321 gcaaaaccta tcaacgtatt tggctcagaa attataatat caccaagcat agcaaaacta
    46381 gcagttactc ctccagtagt agggtcagtt agaactgata tatatggcaa taatttttct
    46441 tcaagcttag aaagtgcttg agaagtcttt gccatctgca taagagatac cataccttct
    46501 tgcattctag ctcctcctga agcagaacaa ataattatag gtaaattatt ttcagcagca
    46561 tactctattg aataagttat tttttcccca acaatagaac ccatacttcc catcataaaa
    46621 tcaggattca ttacacaaat aactgtttta attccattta ttcttccata acctgtgaca
    46681 acagcttctg actcttttgt tttttcctta taagagtcta ctttttcttt gtatttagga
    46741 aaatttagtg gattttgaaa ttctacatca gaattaaact ccataaaagt tcctttatca
    46801 atcaataaat ttattctttt tcttgctctt aagccataat gtcttgaaca ttttggacat
    46861 acaaatgaat tttcttctat gtcctttcta aatacatgac tatcacaacc tttgcaatag
    46921 gtccaaaatt tatcatctac actattcttt ttaaagttgt catctaaaga aatcgtaaca
    46981 tacttagatt cttttgatga taaaaatttt tttatcataa tctatttact ccttataatg
    47041 tagcaaattc tttcttcata aagacatctt ctataaattt ggtatgatga gtatcttctc
    47101 taaactcctc acttgttaca agtgcctttt gaaattctac atttgtatta ataccttcta
    47161 caataatttc gtctagagct ctatatattc tacttataca ttcttctcta gtttcagccc
    47221 aacatattaa cttacctatc atagaatcat ataaaggtgg tatagtatat cctgcatata
    47281 caaaagtatc aaatctaaca ccaaaacctc caggtaaatt taatgattct atcttacctg
    47341 gtgatggagc aaaattcttt gatgaatctt ctgcatttat tctacattca atagcatgac
    47401 ctctaaaagt aatatcttct tgtttaaaag gaattttatc cccattagct atagatattt
    47461 gaagttttat aaggtcaaga tttgttacca tctctgtaac tggatgttca acttgtattc
    47521 ttgtattcat ctctataaaa taaaagtttt tatctttgtc aactataaac tcaatagtac
    47581 ctgcaccgat ataacctact ccttttacta tatctactgc aattttatga agtttttgtc
    47641 tttcttcatc tgaaaggtat ggacttaaag attcttctat tactttttga tttcgccttt
    47701 gcatagaaca atctctatca cctaaatgta ttgcatttga atgtttatct ccaaatactt
    47761 gtacttctat atgtctagga ttttctataa acttttccat atataaatca ctattagaaa
    47821 atgctgctag agcttctgaa cttgccatat caaaatttga aaaaagttct tcttcttttc
    47881 taacgattct catacctttt ccaccgcctc cacttgaggc ttttatcata acaggatatc
    47941 caatttctct tgcaacttct aaagcttctt ccttagtttt caaaacagat tctgaaccag
    48001 gaacaacagg gatattcaat tccatcatag tttctcttgc tctagattta tctcccatca
    48061 aaatcatttg ttctcttgtt ggacctataa aaataatatt attatcttca cattgctttg
    48121 caaattcagg attctctgat aaaaatccaa agcctggatg aatagcatca cactttaatt
    48181 taagagcaag atagattata ttttctatat tattataact cttacttata ttatttggtc
    48241 ctatacaaat agattcatca gctatatatc tatgaaaaca atctttatct atttcagaat
    48301 agatagcaac agtttttata cctagttctt tacatgttct gatgattcta actgctatat
    48361 cgcctctatt tgcaactagt atttttttta tcaacttaaa tacctcctac tacaatggtt
    48421 ttatcttaaa taaaggttga ttatattcta ctagttcttc attactaact aatacttcaa
    48481 ttatttcacc tttaatttca cttgttatct cattcataag cttcattgct tctaatatac
    48541 ataaagtgtc gccttcttca actacatcgc caactttaac aaagctatct gcatctggac
    48601 ttggagaatc atagaatgtt cccatcaaag gagctactac tactgataga ttctcattag
    48661 atgtgacagg tgtatcgttt acaactggct tttctaaaga aagatccact actgattctt
    48721 gttgtacact taaaacaggt gaacttgtag attgagcttt tttagatact tctaatctta
    48781 aatcgctact ttcaagtttt acatattcta agttagttga gtctatggcc tttaataatt
    48841 ccttaatttc attgatgttc attttgttac ccccttgtat tattacctgg tgctaatatt
    48901 atatcacaaa aaacaaattt ataaaagaaa aagtgctgac tagagaatca acacatcaat
    48961 atatctttta attttaaatt aacaaccagt aacttatatt tgttttaatt ttccattatt
    49021 aatataaatt ataagtataa aatgaataaa attcaatatt ttttgcaaaa tacaagagaa
    49081 tacaaattaa tacctcggga atttttaaga caaataccaa tattatgcaa tttagacttc
    49141 gctttctttc aaattagtat cattttcttt atttttacat aggatgtact ttaatttagc
    49201 tatcaaaaca ttgctatata ggttaaaagt tattagaatt gcaggaatta taaagtaaac
    49261 tctagcacct ataaaaccaa aaactactgt aataagtatt aatcttttat ttaaagtaaa
    49321 aaaaggtata ttaaaaatac ttttgtcgga tgtttctgga gtataagaat atataactcc
    49381 aaaaatcaaa gtaagcatac aaagtggaag tagtgtataa cttgaaatta ttcccagaaa
    49441 tcctatactt tcaaaatatt tgctagcact atttgtataa acaaacatgt atccatttaa
    49501 atatgcgcat atacatgata taatgccaaa agttccccct aaggattgag tgtaccaatt
    49561 aaaaaattta gattccatat acctcacctc ctaaaactgt atatataatg atatgcattt
    49621 aaatagtaaa atatatcttt atatgtttct gaataaaatt ttgttaattt cattaattta
    49681 tgtttaagaa atttgaagta tagtgtagta tatattaatg tagatgaagt tttatagtac
    49741 ttatttcata gtgcttaatc aagttatctt attatggatt caaaagttgt ttgtagggtt
    49801 ttatattttg ttgagctgaa aaatttatta taaatgaagg gatgttttcg ctttggtaga
    49861 tacattagaa tttggtctta aaattttatt ttttatatta tcaataattt ggatgggtaa
    49921 aataatgatt ttaagaactg ataagcaaat agtaatcaat cctttgctta ttggtatatc
    49981 tgcagtcctt gtgatgttgc atacctcaca gagtaacatt gaattttttg gattagatgt
    50041 ccaatatata agaatagttt tgtatataat atattcactg ataattttaa taggaatatg
    50101 ggctactaac agaagaaatg gaatttttta gataatctat ttctataaaa tttaaaggtt
    50161 gctagtaaca aagcactaat attagcgttc tgttactaac aacctttatt ttgattatac
    50221 acttaaattg aaaatagaat gattgaataa gttgacagat tattttacat tgacagtaat
    50281 tagaacttct tgagatgtat ttaaatcatt tttgtcgctt agtataactt ttaccactgc
    50341 ttgacctgtt ttattacctt taattatcat atcttcacat gaaagtacac tcttatcact
    50401 tacagataca ataaaattta aatcttttgg aaggttatca gtaacttccc agtatttata
    50461 ataactatca attttcttcg taattatttt tctcaaatca atactttcac cttttgctat
    50521 atcaacgtta tgatatttag agtccagttt atactgatta tcttttgtat caataaaatt
    50581 taaatcgcaa tttacatcca caccattatg agaaagagaa tttactacat cgtcatcaat
    50641 caaataatta ttggcaagat ttattgaatc catatctttt agacttaaag cttccttagg
    50701 aatctctttt atattattat tccaaaaaat aaaattgtct acattttcaa gatatgatat
    50761 accttttaaa tttgaaatgc tctcaccagt tgcataaaat tctccatcta aagcctttat
    50821 attgcttata gtcatctcat ctggatttat atatcttttt acaactgctc ttaaatttgc
    50881 atcaggaaaa atatctttaa gttgattttc gctcaaaacc ttatcatttg aatttattgg
    50941 acttaaagct gctgcagaaa taataaatgg tattaaatta gctaaattca tagtaccctc
    51001 ccacataaat tttttattat aataatttaa tttctatgag agggttctgt ttccttgtta
    51061 tatataccta ctttcgtaca ctttattaat ataaattaaa ataaatttct actattaaac
    51121 ttataaacat attactagtt acgtttttta gcttcacatc taaatattcg cataccttgt
    51181 gacataaatt tgtcttcata ctctgttgta acattatttt catactcact atttcctaaa
    51241 tcaagagaaa tattctttaa tagccaatta tttgcagcaa tttcatttaa actaaactcg
    51301 aataattttt cattatctgt tttaaagtga atttcgccat catcttccaa aaccctattg
    51361 tacatttcta aaaatccaga atgagtgagt cttcttttac tccatctatt tttaggccat
    51421 gggtcacaga aatttatata aattctcgat aattctttag cttcaaagta atccaaaata
    51481 ttgcttacat ctccccataa aaatagtata ttattcaaat tagaagcatc tgctttttca
    51541 acagccttta aaagaacttc ttccttaagt tccatggcaa tataatttat gtcagggttc
    51601 tgcttagcta aagttgttat aaacttacct tttccagtcc caaattcaac atgtattgga
    51661 ttatcatttc taaactttaa attccacttg ccttttaatt tgtctatatc gtctcttaaa
    51721 acatattttg tataacttaa aagcttttca tctgcacctt tttttcgtct tcttctcaca
    51781 ataattctcc ttacatataa aaaattagta aaatacattt ttattataca ttatctcacc
    51841 aaaaaataaa aagaactctc ttaaaataga aatttatttc tataaagaga gttctaaact
    51901 tactaaaaac ttaatcttag tggcaccctg aacaaccaga gcatcctcct ccaccttgat
    51961 ctttcatatt ttcaggaata actctaaatc caaatcctgt atcttctatt attatatctc
    52021 catactgact atattcatca gagctcatta caaattgtaa ttctccaact tcataagtta
    52081 agtcatcttc ttttttctca tctaaagcta atccaaaaga aggacctcca caaccaacac
    52141 ctgcaaagta tactcttata ttattaggtt tatcttgatt gtcttttaag atacttttta
    52201 aagtatcaat agctgtttct ggtaaagtaa ttttcatcaa atcattccct ttcaaatatt
    52261 ttattaaaac aatatctatt atatacccat acaaggtaca taatcaatta gtttttgcat
    52321 attttactaa aacttctacc taatattacc taaggcttta aaatatttta tataatattt
    52381 tattacctta aataaatacc ctatcataaa cttagtaaac aaataaaatt attattctaa
    52441 aaaatataat aattttattt gttgttttaa tattataaca catttgataa tgtccaattc
    52501 atatatgcaa aatttatata ctttaaaata tctaagaaat tattcaataa aaaaatacta
    52561 ttttttaaaa attatcatta ttgataaagc tctactattt atatttttta gtgtattcat
    52621 gtataataag taaaagcaca acggtatata ctgttgtgct tttttgtaat taataaacaa
    52681 tattttggtc tataacaatg aaaaatggct actttccata attgatttca tctgacataa
    52741 gcaaaaaggg tgtccagctg ggtcaatcat aactctccag tcatcagtaa attgctcctc
    52801 tgcgattgta gctccacaat gaattgcata ttgaactgct tcttctaaat cattaacagc
    52861 gaaatccata tgagccattt gctgttgaga ttcaggtttt tctggttcta ttatgcccca
    52921 agcctttgtt ttttgcaata taaagaaaaa attatatatt ttaatatttt ataattgttg
    52981 aaattgtgta ataaattcaa ctggatacat agtgcgtttt gaaatttctt ctaaagctaa
    53041 accttgtttt aaaagcctct ttatgacgct ttccatactt tctgaaattt ctataatatt
    53101 tttatcaaaa tcataaaacc taaaagttct ttgaccccat gggtattctt ttatataatg
    53161 caaaaattca atatttccta ttctatttat cttactttcc cattgtttga tgtcattaac
    53221 ctcaaaatac aactgaaagt tatttgattg ttgatatatt ggtaaatcat atccaattat
    53281 agctttataa ttactttgta atccaaatcc attttcaaat gatacatgtt ctcctaaatc
    53341 taatgtgatt ttttgctcca taacatcttc ataaaacttt tttgatttat ttatgtcttt
    53401 gacaattagc aatactcctc caaatttcat cttatcacta tcctttcttt gttataagta
    53461 ttataactta aaattttgca atttcactgt aaaaatcaga catattagct cggtattttt
    53521 gaggagttat tccacagaca attttaaaat ctttaataaa atgtggtata tcatagaatc
    53581 ctaattcatt acatatagac atcaatgaag ttttattatt gtttagaagt tttatagatt
    53641 tattaatacg taccaaacga gaaaatgact tcatactcaa ccctaggtac tgattaaaga
    53701 gtctgtttaa atgcctagaa ctataaaata cttttttaga aatttcttgt gaagatatat
    53761 ttccagagtt ttgaataatc aactgaattg ccaaaataaa ctcatatgag tattcaattt
    53821 taatattaga aatcaataat tcttccaact ttaaaatcaa tttatctata gataaagatt
    53881 cattaaatat ttttttaatt tctaaatcta atgaagtatt aattatagaa aatggaacaa
    53941 ctttatcaat aagttcactt tgctgtatac ctataagcgg gaaaaaacca gcaggttgaa
    54001 attctataat tagtataaca tcacatctat tagcaatatt tcctactgtt tttggtttag
    54061 tagttggacc aaataataga ctatgtaacc ctgtggcatc ataaaaaaac accaaagtta
    54121 cacttccatg aggaataatc gtgtaattat cagaaattat tgtttgattt ggaaacgata
    54181 tagtaaaatt cgatatccaa tttcttaatt gtatacaagg caagagataa acaaaattgt
    54241 cttcacaaac tataagtgac ctatttttat ttataaaatg aatactttct ttttttaaca
    54301 tatattatat cctgtcctat cgtgaatatt tattaaagta agaagaatcc atattatctc
    54361 tatatatcat taactgcttt taataataga gatagtatga atactcatta gatatttaat
    54421 aaacaaataa aattaaaata atcaataaaa aatatagtac ttttatctgt tattttaata
    54481 ttatagcaca tttatagtat ttaacttata tccactttac atatgtctaa tttatataat
    54541 taaaaatgct tatctcaaat acaataatta gtccttatac aattaaacca tctgaaactg
    54601 taatagtacg actactactt ttggctgctt ctggtgagtg agttaccata attatagttt
    54661 gtccattgtc tctgtttatt ttattcagta aatctattat ttctatccct gttttactat
    54721 ctaaatttcc agtaggctca tcagcaaata gaatctctgg ttttccaatt aaagctcgag
    54781 ctatagcaac acgttgttgc tgaccaccag ataactctcg tggtgtatgt ttacgtctat
    54841 cagttaaacc aactatatct aagatttcat ctaattgatt tttataatct tttaaatttt
    54901 taccatctaa taacaaagga agcattatat tttcctccac atttaaattt ggtattaagt
    54961 tataaaattg aaatacgaat cctatatttc tacgacgtat tatgctcatt ttctcatcat
    55021 taaaatgtga tatatcagct ccattcatat acacttttcc gctcgttgga gtatctaaac
    55081 cacctaaaat atataaaaga gtacttttgc cagaaccaga ttgacccatg atagaaacaa
    55141 attcaccttt cattacttgt aaagatacct cttttaacac tcgagttgtt gtatttccaa
    55201 ttttatattc tttgataata ttttttgctt ctacagctaa actattatgt gtaattttca
    55261 tattaacctc cataattatt caaacttaat ttcttctatc agtttcattt tcttcccttt
    55321 tataataggc actatcgaac ctattaaagt tactataatt cccaataacc caacaataat
    55381 aaatgtttta aaatctaaat ctggtttcat tgaaattttt ggtcctgcaa ctataaagat
    55441 agtttgaatc tcaagtatag atatcacaat accaataaca gctccaagta aacctgaagt
    55501 aaacccttca atcaatgtca cttttatatt ttgtttatta cttagtccta tagatttata
    55561 catagctata gaacgtcttt tttgaatata attaatcagt agattattaa taatacctac
    55621 tgtagcaaga agaaaaatga aataggtcat cttattcata ggagacaaaa aactacttat
    55681 agtatttaaa gaatcattat taaattcttc aactgtacga ctccaattat atgtatctcc
    55741 aaataaatat cttatctgaa tcataacagc atctggattg actgctgtat atactaaaaa
    55801 accataatta gttttatcaa aatcattaac tgcataatgt gatggtataa cagcttctac
    55861 atcatttgcg cgggatttaa aactacctac tattttataa gaaaaatcat acttatcatt
    55921 agatagagtt attgtatctc ctatagataa gcctactttt tttagagtat cttcattcaa
    55981 aataacagaa cgtttatcat taaaagcttc tattacttgt ttttttatct caaaatttgt
    56041 ataattgatt ccaaacatag agttatatag ttttatatta tctgtaccct ctagtcttga
    56101 taatgttaca ccattaccag aaatctcatt attcataaca taaagaggta atattttttt
    56161 aattccatcc atatgtctaa catcttcaat aaactcttca ttcatctttc catctgcaaa
    56221 accttgtaat tctgcgtcac gaaacacatc tgttatataa gttttgacaa agttaccaac
    56281 aacacttatt gcaataactg cagaaatact tataaatagt aaagtgatat tctgtattat
    56341 atttttgtta tttttcatat ttctagcagc taatttaccc tcattcccta aaatattttt
    56401 ataaacaaac tcaaaaacta tagacatgat atcagtaata agaggaatca acacaatagt
    56461 agctacaatt aatcccagta atgaaaatcc accagctaga tacaatgtat tttcagggga
    56521 tattcttgga agtaaaatag ataaaataaa cattatactt cctataaaaa gtatagaacg
    56581 atttgaaaca ttcttttctt ctactgttcc tagtacaata ttttttatcg gcaaatggct
    56641 agctttttta acaggtatat atgcactaaa tgaagaaacg attattgcta ctataacaga
    56701 tataatcact ccaatgggtg atattactac tggaattgat attccttgtt cgagagaatt
    56761 tcctaaccca tgaagcatta aatttaaaac aactacacca ataggaatag caattaatcc
    56821 tcctatactt ccgtataata tactttcaag catcaatata cgagttacag ttttttcatt
    56881 ggcaccaata cttctaaatg ttccaataaa aggaagacgt tctaatgtaa taaccttata
    56941 actgctgtat attataaata tactaagggt taatgcaaaa aaacttatta aaaagaaagg
    57001 cattgtcttt tgtctagcat ctgaaattat cttagtttca tttatagtat ttgataccat
    57061 atatttttca gtagaaagtt ctttggataa tttatttact agattttctg taatttcttc
    57121 ttctgactct ataagaactc ttgtatatcc actgccttta tttataattt ttgatagagt
    57181 ctctttgggt agcagtgcat ttacacctct tgtgttcctc aaaaatactg tatcataaga
    57241 tgcaatatca ctaacttgaa aagtataaga ctttccataa atctgcaaag taatagaatc
    57301 accttttttt attttatatt ttgatgtaaa gcgatttgga agaataattt tatcaccaga
    57361 aaaatcagta atactatcgc cattttctaa tcgtggcttg ttgattttat ttagttgact
    57421 taagtctgct gatataagac taaattcttc atagtatccc cctttattat aaatagcaga
    57481 gctttccaat acaccaacct ttgattttat agcatttaaa tcaggtatgt cttctaaatt
    57541 ggttaatata tctggatttt tactttggac agatatagtc gctgtaccat acataccttt
    57601 tgccattttt ctttgtgcac tttcataaga taatccaatt gagaatgaaa caaaaagtaa
    57661 aactgttgat aaaactatgg acaataacat aactgctgtt ctaatttttc gttctttaat
    57721 atttgtgaaa atatacttta atataatttt caaatttaca ccttctttcc ttatctaaga
    57781 tatttcaatc taatattttt atactttaat ctaaattaaa tctctaatag actcctccat
    57841 acttttatca ttctatttat aatattttta atcaaatcac cccttaaata aaaaagattg
    57901 ataaactact atataaatat aataatctat caaccttaat atatttttta tttgacctta
    57961 attaacctta attaaatagg aaaggtgata taaaatgagc tacctaatcc aggtatactt
    58021 tcaacagata tattccctcc atgaacttca ataatttgct tcgttattgc tagtcctaaa
    58081 ccagttcctt ctattttttg ttttgtattg cttcctctat aataacgatt aaacaaattt
    58141 gatgcttctt ctcttgacat cccttttcca ttatcagata taatgatttc aattctttca
    58201 tttaatgtta tatgtacaca aactttagta tttttatctc catatgtaaa agcattgaca
    58261 ataagattac taaaagctcg ttttaatagt gtacaatcaa aatcaaagtt aatattatct
    58321 atattactct taaattcaac tatatttgat tcatattctg gatagtttaa aatatcaatg
    58381 gataattctt tcaaaaatct tactaaatca taattatttt tatttaaagg gattattcca
    58441 ttttttaatt gataggttaa ttttaaatcg tttataagtg tatttgtata ttctatattc
    58501 tttaacatga ttgaagcata tttatatact ttttcaggtg aataattagt actactatct
    58561 gtaagaagct ctgcataccc ttttattggt gaaagtggag tttttaaatc atgagttata
    58621 tttgaaatcc actcttctct cataatatca gttttatttt gtatctcatc acttctatga
    58681 atttcttcat ttaaaatatt taaactatta tatatatcag caaaaacacc tttaatatta
    58741 actggaagat agcttcgttt tgaaatatcg ctaacagcag atgtaatatt tgatatgcac
    58801 tttgttaccc agtaaccata agcaattcca gaaaccaaaa ttattaaaaa tataatccct
    58861 atgattgaaa atacaattga cttaccacct ataaatttac ctccatcaaa aaacatattc
    58921 actttagata tatttaatgg aaaatatata atataaatat agtcattttt attattttta
    58981 attgtattaa agtatacagt tccattactt gaattatttt ggttagctaa tgctaataat
    59041 tcagaattag aataataatc tttatgctct tttggttcta aaaacccata aactctattt
    59101 ccactagaat ctaaaatttg caaccacaat tgattttctc gaagtttttc taatccagac
    59161 tgttttactt gtggcttatt atctataaat acgatttgtt cattaaagtt ttctgtaaat
    59221 tttttcggcc agtcactacg aataaattcc ccatttggtt tctgaatagt aataagtgat
    59281 aagaaaatac ctattactgt caggattaag caaataaaaa tcatgaaaaa aataatgtat
    59341 gaatgaaata ctgttttata actaggttta tgcatttaat caactctttt cttaaacttt
    59401 tattttgatt attgcttata taaaatagac aataattatt gatatgtaaa aatttattta
    59461 aaa
//
LOCUS       DAMJVG010000014        58865 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.014, whole genome shotgun sequence.
ACCESSION   DAMJVG010000014 DAMJVG010000000
VERSION     DAMJVG010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 58865)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58865)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58865
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.014"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            176..1252
                     /locus_tag="PC512_001011"
     CDS             176..1252
                     /locus_tag="PC512_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDF2440780.1"
                     /translation="MKAQRLNAVLEQMKKDDISQMLVSDPTSIFYLTGVLIHPGERLL
                     ALYLNLNGNNKLFINELFPVSEDLGVEMVWFNDTQNPVEIITEHIDKNATMGVDKNWP
                     ARFLLNLIELGGGSKFVNSSYIIDTLRMCKDEEEKELMRIASKLNDKAMEQLKATVSG
                     ELTEKQLVGKLSKIYEDLGTDGFSFDPIIGFGPNGANPHGEPGNALVKPGDAIILDIG
                     CIKDNYCADMTRTVFYKEIPEKGREIFEIVLEANKRAEAIVKPGVRFCDIDAAARDYI
                     TEKGYGQYFTHRTGHSIGLEVHDKGDVSSINTDTVQPGMIFSIEPGIYLPGEFGVRIE
                     DLVLVTEDGCEILNKHDKEICVVG"
     gene            complement(1369..2211)
                     /locus_tag="PC512_001012"
     CDS             complement(1369..2211)
                     /locus_tag="PC512_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HDF2440781.1"
                     /translation="MDKIKLIVDSACDLPDDIIEKYNIEVVGLNVSFGEESYISGKEI
                     DNETFYRKMSESKVLPKTSCPSPDKFLEAYHCQEESVLVINISSGLSGTYNSALLAKD
                     MFEKEGNNKKVEVIDSLSGSIGIGQLVLKAAILIKEGKEIEEIVSIINKYKDNPPFFG
                     TLETLENAIKGGRINPIAGKIINTLNFKAIIQVADGVVTPIDKARGEGNSLKKLITLV
                     ESKIKDKEEKVLFIGHANCPEKAQKVREVMEKDVKYKDVVICEVGSVMGTYTSKGAIL
                     ITAI"
     gene            2395..2967
                     /locus_tag="PC512_001013"
     CDS             2395..2967
                     /locus_tag="PC512_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2440782.1"
                     /translation="MKTNNMKQAILSSATNLIAKNGVQNTSLADIAKDVNISKGTLYY
                     HYASKDDIIYDIADTHLEVITSAILNCVKNVKSKNSQIEMVNLILEKISTIESRGRVH
                     MYLICEAITSNNDLKERIRLKYIEWRTTLKSEIVESLEKYNSSENEQDAESFSFLLMS
                     IVDGLVVQSLLKTEKIPYENIASFLVNHWI"
     gene            complement(3130..3402)
                     /locus_tag="PC512_001014"
     CDS             complement(3130..3402)
                     /locus_tag="PC512_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440783.1"
                     /translation="MLRERFVVRNHHNPHTSGCCGTGGEGCCGGDNHEHSHQHSHSHG
                     HEHEHVNGVGHDHNHDDGFSGTHEHSHEHTHTHGHEHSDGHTHEHK"
     gene            complement(3529..4401)
                     /locus_tag="PC512_001015"
     CDS             complement(3529..4401)
                     /locus_tag="PC512_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDF2440784.1"
                     /translation="MYGESKKLSIDNNIFLQYCLIILGMILSTLGINLYLAPAKLLSG
                     GVAGICVILYKLFGINQGISSFLMNIPIFIIARKYFDNKFLLISFVNMLLFSLALGLT
                     QDIAKYFPIDDTMLQCIYGGALTGIGMGLTFKARATAGGLDIIAAIMKRKYDIPMKNT
                     FLFINFFVVCAGAFLFGAKLVMYTLITMYIISFTMDIGKDCFDRKKSILLISNKYDEI
                     SKVIMNKMGRGVTFLEAEGAYTQNKKKMIYCIISANEIGKFKDLIYDMDSEAFISVNN
                     VEEVKGGGFKDKFL"
     gene            complement(4688..7795)
                     /locus_tag="PC512_001016"
     CDS             complement(4688..7795)
                     /locus_tag="PC512_001016"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HDF2440785.1"
                     /translation="MAKFKPLVDSSVKQAEAQVFDYWKDINILEKTLEKGKDDPSFVF
                     YEGPPTANGNPGVHHVLSRTLKDSVCRYKTMSGYQVKRKAGWDTHGLPVEIQVEKELG
                     LTSKQQIEEYGIAEFNQKCRESVFSFEKQWRIMTERMAYEVDLDNPYITLDNNYIESV
                     WWILNKFNKEGYIYEGHKILPYCPRCGTGLASHEVAQGYKEVKTNTVIAKFKKKDADE
                     YFLAWTTTPWTLPSNVSLTVNADVDYLKVKKGDEVYYVSKPLADKVLGEDYEVLEEMK
                     GKDLEGLEYEQLMPFVEVDKKAFFITVGDYVTTEDGTGIVHTAPAFGEDDYNTGKRYD
                     LPVIQPVDETGKFTSTPWEGRFVMEDGLDVEIIKWLASENKLYSKEKVVHNYPHCWRC
                     QTPLVYYAKPSWYIEMTKLKDKLIENNNGVKWFPSFVGEKRFGNWLENLNDWAISRTR
                     YWGTPLPIWRCECGHTDSVGSRAELAEKAIEDVNPETVELHRPYVDDIHLKCEKCGKP
                     MTRVTEVIDCWFDSGAMPFAQHHYPFENKENFDQLFPADYISEGIDQTRGWFYSLLAV
                     STFVLGKAPYKSVLVPDLVLDKDGKKMSKSRGNTVNPMELFDQYGADALRWYLLYVSP
                     PWTPTKFDMDGLKEIQSKFIGTMKNVYNFFTLYANTDDINPTEFFVEYKDRPELDRWI
                     LSKFNNLMKDVEENLAIFELNKTLRMIQDFINDDLSNWYIRRSRRRFWATELTEDKKA
                     VYNTTYELLHGLCRAIAPFAPYMSEEMYRNLTGEVSVHLAEYPKCNEELVDTKLEEKM
                     DLAKNLVTLGRASREVERIKVRQPLQKVLVDGKFEDTISDVVDLIKEELNVKEVIFAK
                     DLDEYMNFSLKPNFKEAGPLLGSKMNLFVGALSKLNAHETANKLEKGETLTVDLDGEA
                     FEFNKDLVLIGITAKEGFNVSVENNLFVILDTKLTEELINEGYAREFISKVQQLRKSN
                     NFEVLDNIVIEYCGDDEIAKAVDHFNEYIKSETLALEINRVDDKSLEEQNLNDHMTGI
                     KVIKK"
     misc_binding    complement(7888..8120)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(8295..8822)
                     /locus_tag="PC512_001017"
     CDS             complement(8295..8822)
                     /locus_tag="PC512_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HDF2440786.1"
                     /translation="MLTPIEIENKEFKKGLRGYRDEEVDEFLDIIKEDYESLCRENTA
                     LKEKLGLYQDQVNKYENIEETLKATLITAQSAAEDTCSAANKKAKIIVEEADLKARQI
                     IEQANNRVIEIRKEYDALVKEFKIFRNKFKSLLEDEIRSVDEIFYDVDEKCVNAFEGT
                     TVYNYSNDEAATTLE"
     gene            complement(8857..9642)
                     /locus_tag="PC512_001018"
     CDS             complement(8857..9642)
                     /locus_tag="PC512_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HDF2440787.1"
                     /translation="MDKLKLTNHIKDIDLKNKMFKVIDKANSCIKNYDVKSTEFLNPY
                     EVKNAVAILNSTNEIKYSVDGGYEQAERSTVFIYPFYMEYEDIEDTLRFLQIEGNFKF
                     KNISHKDYLGSILGLGIKREKIGDIIIHDSFCQVVVSSDICDFIIVNLEKVSRNNVIV
                     KEISRENIVNSSSKYKEVSFTVSSDRLDCVISGIYNISRQDSAKYINGEKVHVNYEKI
                     TSTSKIVKNDDLISIRGKGRAKVTQIGDITKKGKIKVQARLIV"
     gene            complement(9652..9909)
                     /locus_tag="PC512_001019"
     CDS             complement(9652..9909)
                     /locus_tag="PC512_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HDF2440788.1"
                     /translation="MGTIRIALYYLLDIIAWMIVIKSLMTWFPNGRQSKIFDILENLT
                     EPIEGPIRSIMYKYTNGPIDFSPLIAIVLLMFLRQLVLVIF"
     gene            complement(9928..10386)
                     /locus_tag="PC512_001020"
     CDS             complement(9928..10386)
                     /locus_tag="PC512_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HDF2440789.1"
                     /translation="MSNGIISKFKNWIVDEEEDYIEDEYESGMDDIVQEEEMNSGFST
                     AKANKIVNLHTTSQMKVVIVEPKVYDEAATIADHLKQRRAVIVNLEGLTNSEVRKSIF
                     NFMNGAVYVLDGSIQKVSKSIFILAPNNVDIDANMKKELESKAFFPWQNK"
     gene            complement(10426..11130)
                     /locus_tag="PC512_001021"
     CDS             complement(10426..11130)
                     /locus_tag="PC512_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HDF2440790.1"
                     /translation="MGSIKDNLSEIRNKIDKAAKKVDRDSKEITLLAVTKTVDVDLVN
                     EAMREGITSVGENKPQELARKYDIIGDKLNWHLIGTLQTNKVKYIIDKVCMIHSLDRI
                     ALCEEIQKRAEQINREIDCLVQVNISKEESKHGLDREEVVDFVKEVSEKYKNIKIKGL
                     MTMAPFIEDEDEIRGVFKGLKDLSKQIKELNIPNVGMDVLSMGMSHDYEIAIEEGATI
                     VRVGTSIFGERNYNKK"
     gene            complement(11140..11775)
                     /locus_tag="PC512_001022"
     CDS             complement(11140..11775)
                     /locus_tag="PC512_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440791.1"
                     /translation="MKKVKYTRLVILGILIYLVFNILVMIISKNVDTLVLKNEKVDAK
                     IHVKGTIEKDANDQSNYLSTYISKEDSNNFEKNQNVIIEYHEQKLDAKVYKIYENNNK
                     IMVKLKISNQIVANQDTSVEEFDIIYNQMECLKIPKTSIKTKDNKRGVYVIDEQSQSV
                     KFVILEGITYENESSVFVDYYKNDINGVTSVNLYDKIILRPNSINTNIRIK"
     gene            12156..13196
                     /locus_tag="PC512_001023"
     CDS             12156..13196
                     /locus_tag="PC512_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2440792.1"
                     /translation="MSEILLGTGLLLLVLCCFTIFSYKAPYGMKAMGALANAACATFL
                     VEAFNLSLLGDVLGMEFFRSVGAANGSLGGVAAAILVPLALGVSPVYAVLIGLSCLDF
                     SILSGFVAGYFVSFLIKFIEKKVPPGVDLVVVILLCAPLSRLIASNVDPLVNSTLLQI
                     GQVLIEATNISPIIMGIILGGLITVVGTSPLSSMALTSIIGLTGLPMAIGALGAFGSA
                     FMNSTLFAKLKLGSKKDIISVAIEPLTQSDIISANPIPIYSTNFFGGAFSGIIVALMG
                     LVNMTPGTATPVAGFAIMFAYNPVQQVLITAGLCALFNVIAGFLGSKIFSTFKVLTAG
                     EIRGTDVEEEIA"
     gene            complement(13659..15014)
                     /locus_tag="PC512_001024"
     CDS             complement(13659..15014)
                     /locus_tag="PC512_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009170073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HDF2440793.1"
                     /translation="MNVGNILETIKMIDEEQLDIRTITMGISLLDCIDPDGDKAREKI
                     YNKIMSSAKDLVKVGKDIEREFGIPIVNKRVSVTPISIIAGATDENDYVKFAQTLDKA
                     AEDLGIDFIGGFSALVQKGYTKGDKILIKSIPKALASTNKVCASVNVGSTRCGINMDA
                     VKEMGEIIKETAELTKDAKGFGCAKLVVFCNAVEDNPFMAGAFHGVGEADRIINVGVS
                     GPGVVKRALEKVKGEPFDVVSETVKKTAFKITRVGQLVAKEASSRLDVPFGIIDLSLA
                     PTPAIGDSVANILEEMGLEVVGTHGTTAALALLNDAVKKGGVMACSHVGGLSGAFIPV
                     SEDAGMIDAVIKGALSIDKLEAMTAICSVGLDMIAVPGNTTAGTLGAMIADEAAIGMI
                     NNKTTAVRIIPAPGCDVGDMVEFGGLLGRAPVMPINTNSSELFTQRGGRIPAPIHSFK
                     N"
     gene            complement(15040..15309)
                     /locus_tag="PC512_001025"
     CDS             complement(15040..15309)
                     /locus_tag="PC512_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HDF2440794.1"
                     /translation="MKAILTVIGKDKPGIVAGISDELYKQNINIVDISQKILQDYFTM
                     IMIVDLEKSLNSFEKTVEDLVERGKKLSVDVKIQREEIFNSMHNL"
     gene            complement(15599..17554)
                     /locus_tag="PC512_001026"
     CDS             complement(15599..17554)
                     /locus_tag="PC512_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440795.1"
                     /translation="MKKYEIFIFMSIIVLCFISFPHKVFGQEENCLEDFERWVQENKN
                     NKEEIVYTLSCDMVIDEEFRFYIPYDSNFTIDTNKYKILIKNHGRFIIDDNELNIIGE
                     GGKEGVIHIENGGSISIGINNIIATDGTALYVEEGGDLHIKSSYESVEKIKANGKDAI
                     GIYTENDIRILNKDIEVNGEHAIGVYSKGDVEIEETSIKAYSSNNESGLLRDNNKLAQ
                     SIISESKKVYIIDDYNELIPSIAEDSGYDIVKCCHRGIGVFSDEIKVSKDDKIENIKF
                     PKYMVLETSSGNRLDIDVEWDFTDYYEKLEKGENFNITGKFKTEMLNKEKIIINDDVV
                     PILNVSVIEKKPIDNLELEFQNTKNGYVAVLFYDMPYSASKVFVEYSSDGINWISEEQ
                     EDIRDQAILFFEDFKLRCFRVKVVGGLKEGYSNIVFKPGFIMGGGDNQETPDDEREND
                     DIDGDRGGGGRDDPDRDEDDNNQDGNNGNENNDSNNNQNNNNENNNNENDNSDEKQPN
                     TPKDDVESSTDSNENKNPHDIPKDGNKENNSDKEKGFYNKNSITENDDNYDLSSKSVF
                     GTNEHSFPYRESISNKNQDTNKNKSNISDYDGIINNNYKLESKEYNLKKDIIFLFCIL
                     TPIMIGSILIVNPDTRKSIIKFIKLKK"
     gene            complement(17737..19212)
                     /gene="spoIVA"
                     /locus_tag="PC512_001027"
     CDS             complement(17737..19212)
                     /gene="spoIVA"
                     /locus_tag="PC512_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage IV sporulation protein A"
                     /protein_id="HDF2440796.1"
                     /translation="MNNNIYEDISKRTQGDIYIGVVGPVRTGKSTFIRKFMEKLVIPN
                     IDNEFKKDRTRDEIPQSGSGKTIMTVEPKFVPADGVEIKIKDTVSLKVRMVDCVGYIV
                     EGALGHEEGGKQRLVSTPWSQEAMTFEKAAEIGTKKVIKDHSTIGIVVLTDGSVTGID
                     RKSYVEPEERVIQELKNLKKPFAVVLNTLSPKSEETSMLRSELEEKYEVPVLPMNVVE
                     MEEEDIEEVMEAVLYDFPLTEIRINLPKWVEGLERNHWIKSSIITTLKQSIIDIGKIR
                     DIEGIIQGFSELEFLEDTGVDNVELGEGVINIDLQTKQDLFYNVLEEKSGFKIEGDYQ
                     LLSLITRLSKVKNEYDKIESALIDAKIKGYGVVAPSLEELSLEEPEIMKQGKQYGIKL
                     KANAPSLHIIKADISTEVSPIVGNQNQGEEMIKYLMEVFEEQPADLWESNMFGKSLHD
                     LVKEQLQSKLYTMPEEIRVKMQKTLQKIVNEGSSNIITILL"
     gene            complement(19384..20679)
                     /locus_tag="PC512_001028"
     CDS             complement(19384..20679)
                     /locus_tag="PC512_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2440797.1"
                     /translation="MSVEVNKPSIWKNFKVLIILFVAGAFIYALPYLKNYYYDTFAQA
                     FNLTNTQMGSLGSIYGLLAMVSYLFGGFLADRISARKLLSGSLIITGISGLVLTLYPP
                     YIVVFLIHALWGITTILTFWPALVKAVRMLASENEQGKAFGFMESGRGITNAIHLSLV
                     LILFGYISSKVSDKSGLTAIIVLYSAINVIVGVLVFFKLKDNEKEVSAKFDKEAFFAV
                     IKMPHTWIITIIMFCSYSANMSFYYFTPYSTEAFGATVVFASAISILAQYCRPVASAA
                     SGLLGDKVGSSKIISYGFILMIAGLLGVIFTPTKSSMIYILLIGCVAIYVSMYAIQGL
                     HYSLLEEGNYSLSISGTAIGIVATLGYLPEVLCPLAAGKILDAFPGVTGYRYYFIVLT
                     IVAIIGLVFTFIWMNMTKERRKELIEMNNNSNENTTKVS"
     gene            complement(20863..22272)
                     /locus_tag="PC512_001029"
     CDS             complement(20863..22272)
                     /locus_tag="PC512_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDF2440798.1"
                     /translation="MKKKIGFWDLVFMNISALFGIRWIAKSTASSFGLGLGSIPVWLL
                     FAFIFFVPASLICAELAATYPKDGGLGEWVKQAYGEKWGFMVSWLNWTSKIFWYSSFL
                     TFLAINIAYMLGNPDLSNNKMFILALSLIIFWLLSLVSTRGMAFGKFFTNTGALGSTI
                     PAILLIVMAFMSVVILKKAPSASIYTIQNIIPKIDANSLVSISAIIFALSGAETTANF
                     ITEMDNAKKNFPKAILTVAVLIGGIYILGSVAITMILPPDKIAASTGILDALAKVAQD
                     LGIGSWFIRIVAFGITLSVLGALILYIAGPVKMLFGNVREGVFPKQLTVTNKYNIPSN
                     AVIVQAIIVSLLLVGTNLLPSVDNIYNVLVTMTALTALFPYVLLFTSYIRLRKTRPNE
                     ERPYSIAKSDSVCINIARMVLVVTVVGILFSTAPVMETLKDNIIYEIEMIGGGLFVII
                     TGLMLWKNYEKKISNNSGR"
     gene            complement(22324..23463)
                     /locus_tag="PC512_001030"
     CDS             complement(22324..23463)
                     /locus_tag="PC512_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDF2440799.1"
                     /translation="MSNNMRLERLRKYMNEKSIEIALIFEPDNQFYISGFKAITYSRP
                     IVTVVTQDKIELIVPGLEELHAKEVAKVDNVYVYYEIPEMKEHGISHKHYLDIILNKY
                     PKGTTVGIEKDIVSASFSEYITDKSFAIKDVGSKIFEMRYVKDAKEIEFLKIAGYLSD
                     IGIKGSLENVRVGMSELEFDVEGDNALLKYVSENYPDTYIGFANWTCSGIDRTAQPHL
                     DSNTRILQRGDIVIHSRQVWYENYRAENERTFIIGKPTERQKEVFKIAVEAQQAGLDT
                     IKAGIPARMVDEAARAVVAKYGLELYSNHRIGHGLGLSEHEEPYLRFDNELILEEGMV
                     FSMEPGIYIPGVGGFRHSDTAIVGKNGATIITNYPRSVEELILDI"
     gene            23782..24432
                     /locus_tag="PC512_001031"
     CDS             23782..24432
                     /locus_tag="PC512_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2440800.1"
                     /translation="MTNKELQKKRILMYFIEAAQNIMENEGIENITLRKVADMAGYNS
                     STLYKYFKNLDHLISFASIKYFKDYNLNISRCIENVNDEYKKYIIMWKLFCKHSFDNA
                     QAFYQVFFNLSSDELSYITKQYYDMFPEDLGIHDSDISLMITGESIKERNKILLNNLV
                     DTGYIPAKDLDIINDIIISFYQNLLFLKKNTGKNSDDDELTMKMISSIEYIIKHAK"
     gene            complement(24589..25608)
                     /locus_tag="PC512_001032"
     CDS             complement(24589..25608)
                     /locus_tag="PC512_001032"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HDF2440801.1"
                     /translation="MEKVCVLGTGSWGSALALGLAKKGNDVSMWTRKEEQAKKINRTK
                     ENTDYLPGVLFPNNITISTDIEKTIKDCKVIVLAVPSQAVRSTCQKIKPFIKEGQVIV
                     NVAKGLEKGTGLRLSQVCEEELPQNPYVILSGPSHAEEVARDIPTTVVVASKDLKIAQ
                     MIQDLFMSPKLRVYTNPDIVGVELGGALKNIIAFGAGICDGLGYGDNAKAALMTRGIS
                     EMSRLGIAMGANMSTFAGLSGIGDLIVTCTSMHSRNRRAGILIGKGMSLEDTLKEVKM
                     VVEGITATEVAHDVAEKLDIDMPITNAIYSVIKKGSNPKEVGIELMMRSKKHEMEEVV
                     LGDDI"
     gene            complement(25639..26253)
                     /gene="plsY"
                     /locus_tag="PC512_001033"
     CDS             complement(25639..26253)
                     /gene="plsY"
                     /locus_tag="PC512_001033"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HDF2440802.1"
                     /translation="MEIFSYIIIAVVAYLLGNISTSYIVAKRIAGVDIRTQGSGNAGS
                     TNVLRTLGKRAGAMTFLGDVLKGVMAVLISEFAARLVGIDTLLAGYLAVICVVAGHNW
                     PAVLGFRGGKGVATSLGAMLAVNPVITLMCLAVFILVVAITKYVSLGSVVGIGCSPIF
                     MIMVKNKAGLIVALFLTASVIYNHRANIKRLLNGTERKIGQKKE"
     gene            complement(26288..27607)
                     /gene="der"
                     /locus_tag="PC512_001034"
     CDS             complement(26288..27607)
                     /gene="der"
                     /locus_tag="PC512_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012063975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HDF2440803.1"
                     /translation="MSRPVVAVVGRPNVGKSTIFNKFAGKRISIVENTPGVTRDRIFA
                     EVEWLDKYFTLVDTGGIEPDSEDIILSQMRNQAMLAMDMSHVILFIVDGKAGITAADK
                     EIAQLLRKTKKPVILVVNKIDSQSQFDNIYDFYELGFGTPFAVSGANSMGFGDLLDEI
                     VENFPAGLDTEYEEDIIRVAITGKPNAGKSSILNKILGEERVIVSPIAGTTRDAIDTY
                     FEKNGQKFLLIDTAGLRRKSKIYETIEKYSVIRAMSAVDRADVVLIVIDALEGVTEQD
                     TKVAGIAHDEGKGCIFVINKWDLIEKDNKTMSNYTKDIKEKFPFMMYAPIVFVSAKTN
                     QRMNKILDTVEYVSNEHSKRISTSALNEVIGEAVMLNQPPSDKGRRLKIYYGTQTDIR
                     PPKITLFINDKDLTHFSYQRYLENKIRENFGFEGTSIKFEYRQKNKK"
     gene            complement(27641..28969)
                     /locus_tag="PC512_001035"
     CDS             complement(27641..28969)
                     /locus_tag="PC512_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF512 domain-containing protein"
                     /protein_id="HDF2440804.1"
                     /translation="MEVNVKKVNNIISKVYKDSIAEEIGIEVGDLLISVNEQPIHDII
                     EYRFLLSDEYLDVEIQKKDGEVYIYEIEKDYDEDLGVEFTNPIIDQAKSCRNKCMFCF
                     IDQLPEGMRETLYFKDDDSRLSFLQGNFVTLTNMSEEDINNIIKYRISPINISVHTTN
                     PELRQKMISNKFAGKLYGIMKRLADTHIEMNCQIVLCPGINDGKELDRTIKELAQLYP
                     YVNSVAIVPVGITKHRENLVELNIFNDKSASKTIEQIHQIQQKYLEKLGTRFAFLSDE
                     FYILSNSELPGYEEYEGFLQFEDGVGMIRKLKTEIEEYLNILPEKILKREKKVSIATG
                     HSAYEFIQSMADAMMDKFKNLQVNVYEIKNKFFGETITVSGLLTAKDLKEQLEDKELG
                     EALYITRSMLKADEEIFLDNIELNQLEELMRIKIIPCLNEGKDFVDKILK"
     gene            complement(29207..29407)
                     /locus_tag="PC512_001036"
     CDS             complement(29207..29407)
                     /locus_tag="PC512_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440805.1"
                     /translation="MGMDIGLNEYTLAIVTLDKNMKNGGGCPIFYANDEKDLQNKALL
                     MSKCVGGMVHDMTNGTLIIVKH"
     gene            complement(29409..30341)
                     /locus_tag="PC512_001037"
     CDS             complement(29409..30341)
                     /locus_tag="PC512_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YIEGIA family protein"
                     /protein_id="HDF2440806.1"
                     /translation="MDRVFFVAVIIGITSRIIMLNLDQKQYPTQPNVLLSQLILAFVA
                     SSLGALLVPALINRSYTSITFLSLAAEQFRQVRANRRNTLQNLEEVQLVKRGAAFIEE
                     IARTYEVRNYMCIVTSFLTIGLYYVILAETKISEGMSLVISSICGLVLAFILKKLLTR
                     KSIGDIADVMPAEISFVDESILKVGDLKGITNIGLKSDREVYINRGVGIQIIPKNKDY
                     ANAGILFDSGQRQAIVYNIYSRLGLYGDYGEPSFVPLPRRNKEDESIMIAYLPVDKNV
                     EKVMEAVKSCPILSSSKGKNLSLKNYKIGKKGSA"
     gene            complement(30386..31318)
                     /locus_tag="PC512_001038"
     CDS             complement(30386..31318)
                     /locus_tag="PC512_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YIEGIA family protein"
                     /protein_id="HDF2440807.1"
                     /translation="MEESLLNANLFRHSFIVALVVGILCRGLVLRVTDKQYPSRPQDY
                     LEQIIISGLSASLGAIALPALIDKEFAALTFFAVAIQQFQGLAEQERITLKNIDNEEL
                     VPKGDAYVEEIASTYESRSYISLFSALVSSIVYIVFARKYGLSFFYCTILAIVSGAIV
                     GLIFRRFLRRNSIADIADIVPAKISFEGPILMVNGVIITNIGLESTREKYRNECLAIE
                     VIPRDLGAFGIVNDIGQRQAIIHNLFIHMGIDRDVDEVDIVAISKTNLEKSTVVIPYM
                     PILKDIDVMIDVVKSTPIIETSKGKQSDFSRKTL"
     gene            complement(31373..32662)
                     /locus_tag="PC512_001039"
     CDS             complement(31373..32662)
                     /locus_tag="PC512_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2440808.1"
                     /translation="MEDLNSIYFFIVMLSIAIVILAVRYTITLRKYLKEFIYVSKKVS
                     NNEYHARLNISAKGELGELARNFNHMIKNMDKTLEEVQYKHLQLRSILKSISHGILAI
                     DVNGNILLINDEAKEMIKSEPNQLVEGHNINVVIKEEEILKQILQFIGSKDNETANIT
                     TKDDIVYKIKVDPVYLQNTNNVIIGSIVNIEDITKKVKLENMRSDFVANVSHELKTPL
                     TSISGFVETLKSNENIDVNTRNRFLEIIESESDRLKRLIDDILLLSFVENKDTLLMEN
                     VVVYDVFKEVYEITQHSASEKNIEVLYKCDDKSISILSNKDYIKQVFLNLVDNAIKYT
                     QDNGIVQVVVLKDEEKIVIKVIDNGVGIPKEDVERIFERFYRVDKARSRDVGGTGLGL
                     AITKHIVKSLNGCIKVKSELGIGSEFIVTILQKNFLK"
     gene            complement(32691..33383)
                     /locus_tag="PC512_001040"
     CDS             complement(32691..33383)
                     /locus_tag="PC512_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2440809.1"
                     /translation="MNTKVLVIDDEMHIVELLKFNLEVSNYEVSYSYDGFDGFIKAKE
                     IKPDLILLDWMLPNISGIEVLRKIRSDKDLKNIPVIMLTAKNMENDKVEGLEIGADDY
                     ITKPFSIKELLARISSVLRRYNLTSLGEENNILTTGNLKLDLSKHEVTKGSEKIELTL
                     KEFELLKLLIQNKGKVLSRNYLLDKIWGYEYYGETRTVDVHIRYLRKKIEDEDKSEKY
                     IETIRGVGYKID"
     gene            complement(33398..34159)
                     /gene="pgeF"
                     /locus_tag="PC512_001041"
     CDS             complement(33398..34159)
                     /gene="pgeF"
                     /locus_tag="PC512_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan editing factor PgeF"
                     /protein_id="HDF2440810.1"
                     /translation="MMKDYINIKNVQDIKEYVNLSGNCEELDEKLNSVNLVITCKNID
                     AKNREDMLKVCKECDLTFENLTSNSQIHSDIVNIVNKDTIGKRRDGDALITNLEKVPL
                     LLFTADCVPISIIDAKNKAIGLAHAGWRGTFSNIGHKTIKLMSECYKTVPEDLVCIIG
                     PSIGPCCYEVSEDLVEKFNTILTNNDEKFYIIKEGSYYLDLWKINEYMLRCSGVKKEN
                     IINLNLCTSCRADKFHSYRKHNKASERIGTVLQIK"
     gene            complement(34156..34617)
                     /gene="nrdR"
                     /locus_tag="PC512_001042"
     CDS             complement(34156..34617)
                     /gene="nrdR"
                     /locus_tag="PC512_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HDF2440811.1"
                     /translation="MQCPYCNYKESKVIDSRHTDLKSIRRRRECESCKKRFTTYEKIE
                     TTPLMVIKKDNSREYFDREKIKYGLLKACEKRPVSIDEIESIVVHIENEINKCFIEEI
                     ETKKIGEMVMDKLKELDEVAYVRFASVYRQFKDINTFVNELKSILIEKGDK"
     gene            complement(34639..34902)
                     /locus_tag="PC512_001043"
     CDS             complement(34639..34902)
                     /locus_tag="PC512_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlmC/YmxH family sporulation protein"
                     /protein_id="HDF2440812.1"
                     /translation="MIRVSDIMEKEIINVKNGKRMGFIIDIDMDIHEGKVVSFTIFGD
                     GSRSFFSRGGDEEVIFWNDILKIGCDTIIVNIGSELSLDEFEI"
     gene            complement(35006..35779)
                     /gene="sigG"
                     /locus_tag="PC512_001044"
     CDS             complement(35006..35779)
                     /gene="sigG"
                     /locus_tag="PC512_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigG"
                     /protein_id="HDF2440813.1"
                     /translation="MQVNKVEICGVNTSELPVLKNKQMKELLLQIKNGDEEARQQFVR
                     GNLRLVLSVIKKFNNRGENIDDLFQIGCIGLIKAIDNFDLSQNVRFSTYAVPMIIGEI
                     RRYLRDNNPIRVSRSLKDIAYKALQVRERLIRTNSKEPTVSEIAKELELEVESVVMAL
                     DAIQDPISLFDPVYQDNGDAIFVMDQVQDKKDTDENWLQEISLKEAIKKLNSREKLVL
                     DLRFYKGRTQIEVADEIGISQAQVSRIEKNALKNMRKYV"
     gene            complement(35871..36593)
                     /gene="sigE"
                     /locus_tag="PC512_001045"
     CDS             complement(35871..36593)
                     /gene="sigE"
                     /locus_tag="PC512_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigE"
                     /protein_id="HDF2440814.1"
                     /translation="MLRLKERIISFITMLGIKLKIIKPKGIYYMGGANILPPPLKPEE
                     EMELLQKLETDESVKSILIERNLRLVVYISRKFENTGIDVEDLISIGTIGLIKAVNTF
                     KLNKNIKLATYASRCIENEILMYLRKNNKKKTEVSFDEPLNIDLDGNELLLSDVLGTE
                     NDEIYKIIEEEIDRDLLVMALDRLSDREKQIMELRFGLIDKGIEKTQKEVAGMLGISQ
                     SYISRLEKKIISRLQKEMKKFV"
     gene            complement(36618..37490)
                     /locus_tag="PC512_001046"
     CDS             complement(36618..37490)
                     /locus_tag="PC512_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-E processing peptidase SpoIIGA"
                     /protein_id="HDF2440815.1"
                     /translation="MFKGFKGGYMVYIEYYVIENLVINYIIISCTSILTKRYNPKKNK
                     LLGASLGGAYSVAYLYPSMNILFTVPFKIIIMSIITLISFRSKSKKDYVHVALVFYLV
                     NIFISGSTYFIIYFTGISHLKISFLIACTYVSCELLKYIYKDLKMLKYIKELTKTINI
                     NLLEKSFCCKALVDSGNLLKDPISQSDVIIVKSSVLEGFIPEKLLNINYEDIDMKKAQ
                     EIIGSLDDKTSGRVRIIPYKHAGSNKTSIIIGLKADYIEVDEQKIGNIILGISNFNDR
                     EYGAIMNPNILPGF"
     gene            complement(37780..39054)
                     /locus_tag="PC512_001047"
     CDS             complement(37780..39054)
                     /locus_tag="PC512_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HDF2440816.1"
                     /translation="MIKLKKVLSLVMVGILSVSILAGCSKKEDSKGKEGKEKLVVWSA
                     PLTDHDADAWKPIFEKFEKENNCEIEFQIVPWDNYAEKYATAISAGEGPDIGYMYAEM
                     FPQFIEMGAVEDLTPYLEKSGTSDNYLYLDDAKMMGGIYGLPIEAANPGVLYYNKDIL
                     EKLGEKPPKTWDDFKRICEKATKDTDGDGKIDQWGLAQGWGSKVFGSLNWNWYPYLWQ
                     AGGDIYNDDLKSVKFNNAEGLKAANFINDMKKYIPEDALSKDSNEMIESVFGPGKAAF
                     TIMLSSAATSTFDKSFPDLNWGYVTSLEDKTVGSFASVDDLTLMSACKNKELGFKLLE
                     YMLSKESMEAFHKEIPRAPVAKGEKYQGDPRFEEMVTRDKHMYRPLTVGPHGVEIYEY
                     LWKQLQMMIAGDITPEQALNESAKYANGLLAQ"
     gene            complement(39338..40495)
                     /gene="ftsZ"
                     /locus_tag="PC512_001048"
     CDS             complement(39338..40495)
                     /gene="ftsZ"
                     /locus_tag="PC512_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HDF2440817.1"
                     /translation="MLNFDVELEECAQIKVIGVGGGGNNAVNRMVEAQLKGVEFISVN
                     TDKQALYTSKAEYKVQIGEKLTRGLGAGANPEVGKRAAEESKDEIVKLLQGADMVFVT
                     AGMGGGTGTGAAPVVAGLAKEMGILTVGVVTKPFAFEGKIRMKNAEGGIAELKSKVDT
                     LITIPNDRLLQIVQKNTSMLDAFAVADDVLKQGIQSISDLIAVEGLINLDFADVTTIM
                     KDKGLAHMGIGSASGETRAIDAARQAIQSPLLETSIQGAKGVLLNVTGGPNLGLFEVN
                     EASTLVMESCDPEANVIFGASIKEDLGDEIMITVIATGFEGLQNGALDLDTKPKSSIR
                     SSLNTTVKQAVKEIEEEVIAEEKIEPPKKASIIEEDDDESMEIPTFLRRRR"
     gene            complement(40685..41038)
                     /locus_tag="PC512_001049"
     CDS             complement(40685..41038)
                     /locus_tag="PC512_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small basic family protein"
                     /protein_id="HDF2440818.1"
                     /translation="MLWVLGGLAFGVVVGYYIPFTYSMDYSIYMSVAILAIMDSIFGA
                     IKSNFEDNYDNVIFITGFIGNAILAILLTYIGEKLGVSLYYVAVLVFGMRLFNNLSII
                     RRYIISNIMNKKRKN"
     gene            complement(41137..41811)
                     /locus_tag="PC512_001050"
     CDS             complement(41137..41811)
                     /locus_tag="PC512_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HDF2440819.1"
                     /translation="MKKKIVILGAFILGVFISTYIKSLDPNRVYITLGQTESIESEVE
                     NTKKEIKNLKETLKKNKKTLNEYKEAKKNGNESIQTLMQKELEEVKELSGYSTVTGPG
                     ITITMRDSERELKDGQNPNDLIIHDIDILRVLNDLKKAGARAISINGERVLATSKIKC
                     SGATITVNDTTYGQPFIIKAIGDIDLLSAAINSPESYAKSLKDIYGINIKVQENNGNK
                     VNLFAK"
     gene            complement(41816..42514)
                     /locus_tag="PC512_001051"
     CDS             complement(41816..42514)
                     /locus_tag="PC512_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HDF2440820.1"
                     /translation="MKKRFINKSIIIGSIVLGVLVSLQLKIINIENRGMTTFKRGEQL
                     TEELKSLKKEKENLQSEVNSVKKDIEIYRGKNNEGEQDILKSEIEKYETLAGYTDVEG
                     TGIKIEINSTKDLGNSDKNDSILYNYDLLLSMINKLNSAQASAISINDQRIVSNTYMY
                     LKEDKLYMNDTVIKEPIIIKAIGDSDTLASALNIKYGIVWEIETYYNAKVKVTKEDNI
                     EINGHSDINKAEGK"
     gene            complement(42537..43277)
                     /locus_tag="PC512_001052"
     CDS             complement(42537..43277)
                     /locus_tag="PC512_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsQ-type POTRA domain-containing protein"
                     /protein_id="HDF2440821.1"
                     /translation="MKKRRKLNTNNVMIVLVFILMLSFCICIIVKSDLFDVKKIDVIG
                     NKRVTKSNIMKELNVNLNENIFAYNFKDMKNKLIKNPYIENVEIKRKLPNKIIISLKE
                     KEIFAVLKDEDNYCYIDKKGNLLEELRGSNESKKDLIVDVDYSIDDNKSIKFKNYKTK
                     ENVFKTLNYLKEEGIYRKINYVNLKKESNIEMLTRSNIKILLSNDDNLDYNISRVSKI
                     LIDLQNKNTNGGTINLNYGKLAVYSPEG"
     gene            complement(43547..44773)
                     /gene="murG"
                     /locus_tag="PC512_001053"
     CDS             complement(43547..44773)
                     /gene="murG"
                     /locus_tag="PC512_001053"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HDF2440822.1"
                     /translation="MKVLLSGGGTGGHVYPAIAIANKIRDEHPDAEIIFVGTEKGIES
                     EIVPKYGFELKTVTVQGFKRKIDFDNVKRVFKLFKGLEQSRKIVKKFKPDIVIGTGGY
                     VSGPVLFNASMGKIPAIIHEQNSFPGVTNKILSKTVTKVLTSFEDSHKRFPEAAEDKL
                     VFTGNPVRKEILLSRKNIARKNLSISDEKRMVLCYGGSGGSRKINDAMRLVIKNMVNE
                     DIAFIFATGKSYYDEFMGSISDINLKPYQKVVPYLEDMANALAASDLVIGSAGAISLA
                     EITALGKPSIIIPKAYTAENHQEYNAKSIEKQGAGIAILEKNLTPESLNTAVFKLLGD
                     RELLVDMANASKTIGKPEAIDLIYDEIMKVYNSTQKSTSKKTKKEKVIKEVKEIKKET
                     TPSIEGQAKVIGIKKR"
     gene            complement(44791..45921)
                     /gene="spoVE"
                     /locus_tag="PC512_001054"
     CDS             complement(44791..45921)
                     /gene="spoVE"
                     /locus_tag="PC512_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein E"
                     /protein_id="HDF2440823.1"
                     /translation="MPKENLKKQIDIRMKTEFDGVVFYTTMLLVFVGIVMVFSASFIQ
                     SSFKHNDAYYFLKKNVIYAVLGFIVMIITSRIDYSFWKKNATAIGAIAVVLLLLVLTP
                     LGIEANGAKRWLGIGALTFQPAEIAKFATIILTAKLIEKNYDKIKSLTKGVVPLLVVP
                     GIFFALIILQPNLSTAGTVILVTFVMIFVAGMDMKIVFAMIGSGAALFAALVIAEPYR
                     LSRVTSFLDPFQDPLGKGYQVIQGLYALGSGGLFGLGLGKSKQKYFYIPEPQNDFIFA
                     IIGEELGLIGCIIVIMLFVVLVYRCVRIALKTSNVFACMVVIGIGAQIGIQAALNIAV
                     ATSSMPATGVALPFISYGGTSLTIFMGAVGIVLNISKHVKIN"
     gene            complement(45973..47328)
                     /locus_tag="PC512_001055"
     CDS             complement(45973..47328)
                     /locus_tag="PC512_001055"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HDF2440824.1"
                     /translation="MDLKGKKVLLVGLAKTGISTIKHLDKLGASVIVNDIKDENKLRN
                     ILDELKSINDIKYILGHHPEDVDDIDMVVVSPGVPLDLPFILKLKNSGKYIIGEVELA
                     FKLSNNPIFIGITGTNGKTTTTSLVGEIFSRAKRDTYVVGNIGNPVIDTIETSSEESV
                     LVTELSSFQLESIDEFRPKVSAILNITEDHLNRHHTMEKYIEAKANIFMNQTVEDFCV
                     LNYDDEIVKSLADKCNAKVIYFSRTKKVNGGVYLENNDIIIDIDDKIKFLNKDDVSLP
                     GGHNLENCMAAIAIAYVCKIDLEVIKDVLMTFKGVEHRQEFVRNLDNVIYVNDSKGTN
                     PDSTIKAIQSYDRPIILIAGGMDKGSNFDELLETAKSYVKSLVLLGETASNIENCAKN
                     KGFNDIHIVKDMEEAVKTSYEISKSGDIVLLSPACASWDMYESFEVRGKDFKDNVNNL
                     K"
     gene            complement(47347..48315)
                     /locus_tag="PC512_001056"
     CDS             complement(47347..48315)
                     /locus_tag="PC512_001056"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HDF2440825.1"
                     /translation="MMLGITELTYTALIAFLIVIIIGPIFIPMLRKFKFGQTVRDDGP
                     QTHLAKNGTPTMGGIIMIVAILITGLTRVKVSHDMAVGLICIAGFGFIGFLDDFIKIK
                     LKRSLGLKAYQKIILQVALSFYVAFYQYTSSSSASQLMIPFTDFVINVGILYIPIMMF
                     IIVAIVNAVNLTDGLDGLASGVTLIVSVFFMLFASSIAGNTEVAVLAAATVGACLGFL
                     GFNSYPARVFMGDTGSMALGGAVVAFSVLTNSVLIIPIIGGIYFAEALSVLIQVGYFK
                     ATRKRFFKMAPIHHHFEQCGWPETRVVFIFWIITVVLAWISIIAVF"
     gene            complement(48356..49729)
                     /locus_tag="PC512_001057"
     CDS             complement(48356..49729)
                     /locus_tag="PC512_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HDF2440826.1"
                     /translation="MECLTIKELVLATNGKLIYGDYNDCVSDIVIDSREANAQNAFVA
                     IVGENLDGHTFMKSAYDSGCKTFIKNESNGIKLESSDINLIEVKDTSLALGDISKYYK
                     EKFDIPFIGVTGSVGKTTTRDMIYSAISAKLNILKNEKNLNNHFGVPLTLFNLNKEHE
                     CAVIEMGMSGFNEIKYLVDIVNPKIAVISNIGLSHVEKLGSQEGILKAKMEITSNFDE
                     TNTLIVNGDDKFLSTLKEKEHVYKLKTFGFNKNNDVYCESYTMEEDSLTFICVINGKK
                     EEIFIPTIGEHNIYNAMSAILVGLCLNISLDYIKKGLKNFKGTKMRLDIIKNEKLTII
                     NDSYNASPDSMDAALKILGRYKGRRVAILGDILEMGEISEYGHRLVGKSSMNNTDIII
                     TIGENSVFIGEEAKQLGFNSANIYHFENREDVFNKLNELVKTGDTILVKGSRGMRLEK
                     IVEYLNK"
     gene            complement(49896..51875)
                     /locus_tag="PC512_001058"
     CDS             complement(49896..51875)
                     /locus_tag="PC512_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein D"
                     /protein_id="HDF2440827.1"
                     /translation="MRKVKRISKKRLVLVLILACALFFCLVIRTGYLQLMKGNWLSTK
                     ALEQQTRDIPIEPKRGTIYDRNMKELAVSVTKYTVWCKPVEVEDKKEAAEKVAEILDE
                     DYKDIYALISKKNMALVKVKRWIDDDKASQIRDAKLSGIWVAEDNQRYYPYGNFAPYV
                     LGHTSSDATGISGVEMQYDKKLKGKPGKLIVSTDASGREIPQGMEKYYEPVQGNGLVL
                     SIDEVIQHYTEKAVQKAYELNNAKKVTAIAMNPKTGDILALASKPDYDPNDSRTPIYP
                     YYQEELEKYNDKDKIKGYYQMWRNPAVSDTYEPGSTFKLITSSSALEEGVIKDGEKFT
                     CTGSVTVGGRKIKCWRHYRPHGTQEFKQAVQNSCNPVFVELGSRLGVGKMYDYIESFG
                     LMDKTGIDLPGEAKGILYNEKNVGPVELATISFGQSISVTPIQLITAISSIANGGDLM
                     QPRVVKSYTDNKGNITETVKPKKVRSVISKETSKKMLEIAESVVTEGGGKIAYIPGYR
                     LGGKTGTAQKVIDGKYAPGKYICSFVGIAPCDDPQIVVLAIVDEPTGVSAFGSTTAGP
                     IVKEIMNDSLKYLGVKPVYKEEEKAEYEKKQVKVPDVRNLKIGDAVKALEDAKLKPDL
                     DADIELPEDTKVKDIFPKPGVKVNEDSSITLYFEN"
     gene            complement(51887..52234)
                     /locus_tag="PC512_001059"
     CDS             complement(51887..52234)
                     /locus_tag="PC512_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440828.1"
                     /translation="MKKNYKIHNLNEYKNKKKNNYKKRNKKKIGAKCILLIATFSVII
                     LNLCGYSKISEMKYDIYYLQKDLRKKEIVLEELKAKETEKTSIKEIELKAKELLNMDY
                     PKDGQIKYIDVDN"
     gene            complement(52720..53655)
                     /gene="rsmH"
                     /locus_tag="PC512_001060"
     CDS             complement(52720..53655)
                     /gene="rsmH"
                     /locus_tag="PC512_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HDF2440829.1"
                     /translation="MEFHHVSVLLNECIENLNIKPDGVYVDCTMGGAGHSKEIVKKLS
                     DKGLFIGFDQDKNAISTAKERLSEYESRVKFVHSNFENIKEELEKIGVYKIDGVLADL
                     GVSSHQLDEADRGFSYMQDAPLDMRMDVRCEFSAYDVVNTYTEDELTKIIKDYGEDNW
                     AKRIAKFIVEERANKPIETTGELVDVIKKAIPKKARIDGPHPAKRTFQAIRIEVNNEL
                     GVITKMINDASSIMNEGGRICIITFHSLEDRIVKNAFKHLASDCICPQHLPICQCDKE
                     SEVKIITRKPILPSEEEIEVNPRSRSAKLRVAEKI"
     gene            complement(53685..54431)
                     /locus_tag="PC512_001061"
     CDS             complement(53685..54431)
                     /locus_tag="PC512_001061"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HDF2440830.1"
                     /translation="MDRVAFTLFGIDIMWYGILMACGMILGTLIAIKEAKRVGIKEDD
                     VLNIAIIAIPVGLICARIYYVVFNWSYYAQNMSQIFNFRGGGLAIHGGLIGGILAGYI
                     YTKIKNINFLKMADTVILGMPLAQAIGRWGNFINGEAHGGATNLPWGIMVDGVKVHPT
                     FLYESIWDFGIFIVLLLFRKNKKYEGQVIVTYITLYSIGRFFIEGLRTDSLMLGPLRM
                     AQVISLIGVIGGIIAHVYLSKKNKNNISEE"
     gene            complement(54825..56111)
                     /locus_tag="PC512_001062"
     CDS             complement(54825..56111)
                     /locus_tag="PC512_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HDF2440831.1"
                     /translation="MEKIVNDILKEEVYYEKLQNGLDVYFMPKRGFMKKYAILATNYG
                     SNDLEFVPIGEDKKIRVNEGIAHFLEHKMFEQPDGGDAFDKFSKLGVNANAFTNFTMT
                     AYLFSATENFYESLEHLIDYVQTPYFTDENVEKEKGIIAQEIKMYNDDPDWNVYFNCL
                     KAMYVNYPARIDIAGTVDSIYKITKEELYKCYNTFYNPGNMALFVVGDLDVEKVIDVT
                     KKSNNYKVDKLSKSIERFYPEEPEGVKEKEVIEKFPISMPMFNIGFKDSNVGLKGKEL
                     LRKEIVTDILVGMLFKKGSKLYEDLYMQGLINENFGAGFSSQVDYAFSIIAGDSKEPK
                     KVKEIILDYIEKSKKEGLSKEEFERTKKKKIGSFIKCFDSINFIGNSFISYVFKDINL
                     LEYLDVIKDITFEEVEERLKEHFKEEYCVISIVEPK"
     gene            complement(56126..57391)
                     /locus_tag="PC512_001063"
     CDS             complement(56126..57391)
                     /locus_tag="PC512_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HDF2440832.1"
                     /translation="MVNTKKIINLGNNINLTLIKTEKFKSNLISLYVQRLLDEKETTK
                     NALIPSIIASGSSKYPSARAISNKLDDLYGSSMGADAVKRGERQVLSFKVINISEKYL
                     DESIFEEVVEFFNEVINNTLVVDGGFKEEYLNIEKENLREKIQSIINDKKEYAQDKCI
                     EAMCKGERYSVSEFGYEDEIDSITSRELYEHYKNILKTSPIDIVVEGNFDEDKVVDII
                     SKNLKFEREEIINIPRADFIKNVDEVKVIDEQMEITQGKLVMGYRANVDYADIDKYYA
                     LVVGSNVLGGGPHSKLFVNVREKESLCYYIFSSIEKYKSIMFISSGIETKDYDKAVEL
                     IKKQVESVKAGDISDEELENSKLALVNSMKSITDNIGGMSDFVFSQSMAKTNSEVQDI
                     ISSIEKVTKKDIVEAIKNIELDTVYFLRN"
     gene            57707..58804
                     /gene="ychF"
                     /locus_tag="PC512_001064"
     CDS             57707..58804
                     /gene="ychF"
                     /locus_tag="PC512_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HDF2440833.1"
                     /translation="MKLGIVGLPNVGKSTLFNAITQAGAESANYPFCTIDPNVGVVSV
                     PDERLNKLQELYNSEKIVPTAIEFCDIAGLVRGASKGEGLGNKFLSHIREVDAIVHVV
                     RCFEDENVVHVDGSVDPLRDIETINLELIFSDIEILERRINKTQKAAKADKTLGSELD
                     LLKSIMSTLEESKCVRTMEFTEDEQTFVNSLDLLTSKPVIYASNVSEDDLADNGENNK
                     YVQQVKAFAETEDAEVVVVCAQIEAEISELDSAEEKKEFLETLGLEQSGLDKLIKSSY
                     ALLGLISFLTAGPKEVRAWTIKVGSKAPQAGGKIHSDIERGFIRAETIAFNDLVEHGT
                     MAAAKEKGLVKLEGKEYIVKDGDVILFRFNV"
BASE COUNT        18445 a        10671 c         6336 g        23413 t
ORIGIN      
        1 attttcacaa taaaaagtca ttttacttcc gtatttaatg caaaagtaga gattaaactt
       61 aatataaaaa atatataaca aatttttttt atatttctag aagaaaagta tactcttttt
      121 tgtttaataa tgctaaaatt gatttgtatt gaattttgat taggaggaaa ttattatgaa
      181 agctcaaaga ttaaatgctg tacttgaaca aatgaaaaaa gatgatattt ctcaaatgtt
      241 agtaagtgac cctacttcta tattttatct tacaggagta ctaatccatc caggcgaaag
      301 actattagca ttatacttaa atttaaatgg caataataaa ttatttataa atgaattatt
      361 cccagtttca gaagatttag gtgttgaaat ggtttggttc aatgatactc aaaatccagt
      421 agaaataata actgaacata tagacaaaaa tgctactatg ggtgttgata aaaactggcc
      481 agctagattc ttattaaact taatagaatt aggtggagga agtaagtttg taaattcatc
      541 ttatataata gatactttaa gaatgtgtaa agatgaagaa gaaaaagagt taatgagaat
      601 agcttcaaaa ttaaatgaca aggctatgga acaacttaaa gctactgttt ctggtgaact
      661 tacagaaaaa caacttgttg gtaaattatc taaaatatat gaagacctag gtactgatgg
      721 attttcattt gaccctatta taggttttgg acctaatgga gctaatccac atggtgaacc
      781 tggaaatgca cttgtgaaac caggagatgc aataatctta gatataggtt gtataaaaga
      841 taactattgt gctgatatga caagaactgt attctataaa gaaatacctg aaaaaggtag
      901 agaaatattt gaaatagttc ttgaagctaa taagagagct gaagctattg taaaaccagg
      961 tgttagattc tgtgatatag atgctgctgc tcgtgactac ataactgaaa agggatatgg
     1021 acagtacttc actcatagaa ctggtcactc tataggactt gaagttcatg ataaaggaga
     1081 tgtatcttct ataaatacag atactgtaca accaggaatg atattctcta tagagccagg
     1141 tatatattta ccaggtgagt tcggagttag aatagaagat ttagtacttg ttactgaaga
     1201 tggttgtgag atattaaaca aacatgacaa agaaatatgt gtagttggtt aattctaaaa
     1261 tcaatttgat aaaattaaaa agccatataa aaatgtttta aacattttta tatggcttta
     1321 atttctcaat ctatgattta tttcaatcca ttatttatat tgcagtattt atattgcagt
     1381 tattaagatt gcaccctttg aagtatatgt ccccatcact gaaccaactt cacagattac
     1441 aacatctttg tattttacat ccttttccat aacttccctt accttttgag ccttttctgg
     1501 gcaattagca tgtcctataa ataaaacctt ttcttcttta tctttaattt ttgactctac
     1561 taaagtaatc agctttttca aactgtttcc ttcacctctt gccttatcta taggagttac
     1621 aacgccatct gcaacttgta ttatcgcctt aaaatttaag gtatttataa tttttcctgc
     1681 tattggattt attctaccac ccttaatagc attttctaaa gtttcaagtg ttccaaaaaa
     1741 tggaggatta tctttatatt tatttattat tgaaacaatc tcttcaattt cttttccttc
     1801 ttttattaat attgctgctt ttaacactaa ttgtcctatt ccaattgacc cactaagtga
     1861 atctataacc tcaactttct tgttatttcc ttccttttca aacatatctt ttgctaaaag
     1921 tgcactatta taagtcccag ataatcctga acttatatta atcactaata cactttcttc
     1981 ctgacaatgg tatgcttcta aaaatttatc aggagaagga catgatgttt ttggtagtac
     2041 tttactctca ctcatttttc tatagaaagt ttcattatct atttcctttc cagatatata
     2101 actttcttct ccaaaagata catttaaacc aacaacttct atgttgtatt tttctattat
     2161 atcatcaggt aagtcacatg cactgtccac tatcaatttt attttatcca tattaacctc
     2221 actataagat attattttat ttattcagtc ggtcgtacga ccgatttaat tattatttta
     2281 tatattgaat gaaaaaaagt caatagatat agattctcgc tttattgaca ataaatatcc
     2341 ataagcttat aatgttatta atttgttata aatatacatg gaaaggtagg ttttatgaaa
     2401 acaaataata tgaaacaggc tattttatca tctgcaacca atttaatagc caaaaatgga
     2461 gttcaaaata ctagccttgc tgatattgca aaagatgtaa atataagtaa aggtactttg
     2521 tattatcact acgcatctaa agatgatatt atatatgata ttgcggatac tcatttagaa
     2581 gttataacta gtgctatact aaactgtgta aaaaatgtca aatcaaaaaa ttctcaaata
     2641 gaaatggtta acttaatctt agagaaaata tctactatag aaagtcgtgg tagggtacat
     2701 atgtatctta tttgtgaggc aattacttca aataatgatt taaaggaaag aataagatta
     2761 aaatatattg aatggagaac tactcttaaa tctgaaattg ttgaatcact agaaaaatat
     2821 aatagtagcg aaaatgaaca ggatgctgaa tcattttctt ttttactcat gtcaatagtt
     2881 gatggtttag ttgtccaaag tttattaaaa acagaaaaaa taccttatga aaatatagct
     2941 tcttttttag ttaatcattg gatttaaact taatacttag ataattaata aaagtgaact
     3001 atttaagtta tctactttaa cagttcactt tcttatttat tctcaataat ttttacttaa
     3061 aacattcaat ttttatttaa accttcatgg aatcacaaaa taaaaatctc ttataaattt
     3121 aaaatgtttt tatttatgtt catgtgtatg cccatctgaa tgttcatgac catgtgtatg
     3181 tgtatgctca tggctatgct catgagtacc tgaaaaacca tcatcatgat tatggtcgtg
     3241 acctacacca tttacatgct catgttcatg cccatgactg tgagaatgtt gatgtgaatg
     3301 ttcatggtta tctcctccac agcatccttc tcctccagtc ccacaacacc cacttgtatg
     3361 tggattatga tgatttctta ctacaaatct ctctcttaac ataattctta tacctcctag
     3421 tatattattg agtacttcat gtaccccatt aactatggta tacatctaac taggtataat
     3481 ctcaatacat atgtcatttt ttaacatata taattaacat atataatctt aaagaaattt
     3541 atccttaaaa cctccacctt ttacttcttc aacgttattg acagaaataa aagcttcact
     3601 atccatatca taaattaaat ctttaaattt acctatttca tttgcagata ttatgcaata
     3661 aatcatcttt ttcttatttt gtgtatatgc accttctgcc tccaaaaaag tgactcctct
     3721 acccatttta ttcattatca ctttggatat ttcatcatat ttatttgata ttaaaagtat
     3781 agattttttt ctatcaaagc aatcttttcc tatatccata gtaaaagaaa ttatatacat
     3841 tgtaattaaa gtgtacatca ccaatttagc tccaaataaa aaagctcctg cacatactac
     3901 aaaaaaatta ataaataaaa atgtattttt cataggtata tcatactttc ttttcattat
     3961 ggctgctatt atatcaagtc ctccagcagt agctcttgct ttaaaagtta accccatacc
     4021 tataccagtt aatgcaccac cataaataca ctgtagcata gtatcatcta ttgggaaata
     4081 tttagcaata tcttgtgtta gccccagtgc tagagaaaat agtaacatat tgacaaaact
     4141 tattagcaaa aatttattat caaaatactt tctagctata ataaatattg gtatgttcat
     4201 caagaaactt gatattccct gatttatacc aaataatttg tataatataa cacaaattcc
     4261 agctactcct ccacttaata acttggctgg tgctagatat aaatttattc ctaaggttga
     4321 tagaatcata cccaatataa tcagacaata ttgtaaaaat atattattat caatacttag
     4381 ctttttactt tcaccataca tcaaaacgca cccctttgca taataaataa accaccctgc
     4441 ataacacacg ataaatttac aaataaattt atcagaagta gtttcctaaa aatattattc
     4501 atcctcactt aaacgtttat tcattaatat tctatcacat gacataaata atttatatga
     4561 tttatacaga tttatttatt gtaaattttg gaatattaaa acattttatt gaatagataa
     4621 ttatattaca taaaaaatcc ctatagaaat ctataaacta atttctatag ggattttgat
     4681 taactaacta tttttttata acttttatac ctgtcatatg gtcatttaag ttttgttcct
     4741 ctaaagattt atcatctact ctgtttattt ctaaagctaa agtttcagac ttgatatatt
     4801 cattaaaatg gtcaacagct ttagcaattt catcatcacc acagtattct attactatat
     4861 tatctaatac ttcaaagtta ttagattttc ttaattgctg tactttagat ataaattctc
     4921 tagcataacc ttcattaatc aactcttcag ttagcttagt atctagtata acaaaaagat
     4981 tgttttcaac agatacatta aatccttcct tagcagttat acctattaat actaaatcct
     5041 tattaaattc aaaagcttca ccatctaaat caactgttaa agtctcacct ttttcaagtt
     5101 tattagcagt ttcatgagca tttaatttac ttaatgctcc aacgaataaa ttcatcttag
     5161 aacctaataa tggccctgct tccttaaagt ttggttttaa actaaaattc atatactcat
     5221 ctaaatcttt agcaaatatt acctctttaa cattaagctc ttcttttatt aaatcaacta
     5281 catcacttat tgtatcttca aacttaccat ctactaacac tttttgtaat ggttgacgaa
     5341 cttttattct ttctacttct cttgaagctc tacctaaagt aactaagttt ttagctaaat
     5401 ccattttttc ttctaattta gtatctacta actcttcatt acatttagga tattcagcta
     5461 aatgaacaga tacttctcct gttaagtttc tatacatttc ttctgacata tatggtgcaa
     5521 atggagctat agctctacaa agaccatgta acaattcata agttgtattg tacactgctt
     5581 ttttatcttc tgttaattca gttgcccaaa atcttcttct tgaacgtctt atataccagt
     5641 tagataaatc atcatttata aaatcttgta tcattcttaa agttttattt aactcaaata
     5701 tagctaaatt ttcttctaca tctttcatta aattattgaa cttagataat atccatctat
     5761 caagttctgg tctatcttta tattctacaa aaaattcagt tggatttata tcatctgtgt
     5821 ttgcatataa agtaaagaag ttatatacat tcttcatagt acctataaat ttactttgga
     5881 tttcttttaa tccatccata tcaaatttag ttggagtcca tggtggagaa acatatagta
     5941 aataccatct taatgcatct gctccatatt ggtcaaataa ttccattgga tttactgtat
     6001 ttcctcttga tttactcatt ttcttaccat ctttatcaag tacaaggtct ggaactaaaa
     6061 cactcttata tggtgctttt cctaatacaa atgttgatac tgcaagtaat gagtagaacc
     6121 aacctctagt ctggtctata ccttctgata tatagtcagc tgggaacaat tggtcaaagt
     6181 tttccttatt ttcaaatgga tagtggtgtt gagcaaatgg catagcccca ctatcaaacc
     6241 aacagtctat aacctctgtt actcttgtca ttggttttcc acatttttca cattttaagt
     6301 gtatatcatc tacatatggt ctatgaagtt caactgtttc tggatttaca tcttctatag
     6361 ctttttcagc taattcagct cttgaaccaa ctgaatctgt atgaccacat tcacatctcc
     6421 atataggaag tggagttccc caatatctag ttcttgatat tgcccagtca tttagatttt
     6481 ctaaccagtt tccaaatctc ttctctccta caaaacttgg gaaccatttt acaccattat
     6541 tattttctat taatttatct ttaagtttag tcatctctat ataccagctt ggttttgcat
     6601 agtatactaa tggagtttga catctccagc agtgtggata attatgaact actttttctt
     6661 tgctatataa tttattttca gaagctagcc attttattat ttcaacatct agcccatctt
     6721 ccattacaaa tctaccttcc caaggagtag atgtaaattt accagtttca tctactggtt
     6781 gaataactgg taaatcatat cttttacctg tgttgtagtc atcttcacca aatgctggtg
     6841 ctgtatgaac tataccagtt ccatcttcag tagttacata atctcctact gtaataaaaa
     6901 atgctttttt gtcaacttct acaaaaggca ttaattgttc atattctaaa ccttctaggt
     6961 ctttaccttt catttcttct aaaacttcat aatcttcacc tagtacttta tcagctaaag
     7021 gtttagatac ataatatacc tcatcacctt ttttaacttt taaataatct acatcagcat
     7081 ttactgttaa tgaaacattt gatggtaaag tccatggagt tgttgtccat gctaagaagt
     7141 attcatcagc atcttttttc ttaaatttag ctataactgt attagttttt acttctttat
     7201 atccttgtgc aacctcatga ctagcaagac cagttccaca tcttgggcaa taaggaagta
     7261 ttttatgccc ttcatatata tatccttctt tgttgaattt gtttagtatc caccatacag
     7321 actctatata gttattatct aaagttatat atggattatc taaatcaact tcataagcca
     7381 ttctctcagt cattattctc cattgttttt caaatgagaa aactgactct ctacattttt
     7441 ggttaaattc agctattcca tattcttcta tttgttgctt actagtaagt cctaactctt
     7501 tctctacttg tatttcaact ggtaatccat gtgtatccca accagctttt ctctttactt
     7561 gataaccaga cattgtttta tatctacaaa ctgaatcttt aagcgttcta gataaaacat
     7621 ggtgtactcc aggatttcca ttagctgttg gaggtccttc atagaatacg aaacttgggt
     7681 catctttccc tttttctaaa gttttttcaa gtatatttat gtctttccaa taatcaaaaa
     7741 cttgtgcttc tgcttgtttt acagaactgt ctaccaatgg cttaaatttc gccatgtaaa
     7801 tcaccctttc ctactaaata ttataattcc aaaatttttt attctttcac ataaatttaa
     7861 atactaaaaa actcgccccc tttaaaccaa agggacgagt tataaatcgc gttaccaccc
     7921 taattctata tgtaaactaa atactagcta catataacac tctaatagta taacggtact
     7981 aaccggcaca gcttagtaga atttaatcgt tcagcctgca gctcaagagt gatttttatc
     8041 tttataaatt cattggttct cagcataccc aattctctgt aaaattatct aaagataaat
     8101 gtctctatca acgcttttaa aaatttatct gtgtttatat gaaattctat aacaaataat
     8161 ttgaatagtc aatatatttt tgaaaaatat aataatttct atttttctta catttttatc
     8221 ctatttttaa tctttgttat agatttctca aactcacaca attattctac ataaaaaata
     8281 aacaaattac aagcttattc taaagttgta gcagcttcat cattactata attatacact
     8341 gttgttcctt caaatgcgtt tacacatttt tcatctacat cataaaaaat ctcatcaaca
     8401 cttcttattt catcttctaa cagtgattta aatttatttc taaatatctt aaattctttg
     8461 actaaagcat catactcttt tcttatctct ataacacggt tattagcttg ttctataatt
     8521 tgtctagctt ttaaatcagc ttcttcaaca attatcttag cctttttatt agccgcgcta
     8581 caagtgtctt ctgctgcact ttgagcagtt attaaagtag cttttagtgt ttcttcaata
     8641 ttttcatact tgtttacttg gtcttgatat aaccctaatt tttctttaag agctgtattt
     8701 tccctacata gagattcata atcttccttg atgatatcta aaaattcatc aacctcttca
     8761 tctctatacc ctcttaaacc ttttttaaac tctttatttt ctatctcaat tggagttagc
     8821 attacatttc ctcccagcta taatttaaat tagtccttat acaattaatc ttgcttgaac
     8881 ttttattttt ccttttttag taatatctcc tatttgtgtt accttagctc ttcctttgcc
     8941 tctaatagaa atcaaatcat cattttttac tattttagaa gttgaagtta tcttttcata
     9001 attgacatgg actttttctc catttatgta ttttgcacta tcttgtctag atatattgta
     9061 aataccactt atcacacaat ctaacctatc tgaagatact gtaaatgata cttctttata
     9121 ttttgaagaa ctattaacaa tattttctct ggaaatttcc tttacaatta cattatttct
     9181 tgaaaccttt tctaagttta caattataaa atcgcaaata tcactactta caactacttg
     9241 acaaaagcta tcatgtataa ttatatctcc aattttttct ctttttatac ctagacccag
     9301 tattgaccct aagtaatctt tatgagatat atttttaaat ttgaaattcc cttctatttg
     9361 taaaaatcta agagtatctt ctatatcttc atattccatg taaaatggat aaataaatac
     9421 agtgcttctt tcagcttgtt cataacctcc atccacactg tattttattt catttgtaga
     9481 atttaatatt gctacagcat ttttcacttc atatggatta agaaactccg tagacttaac
     9541 atcatagttt tttatacaac tattagcctt gtctatcact ttaaacattt tatttttcaa
     9601 gtctatatcc tttatgtgat ttgttagttt taatttatcc atcctatcac cttagaatat
     9661 aaccaatact aattgtctta ggaacatcaa taatactatt gcaattaaag gagaaaaatc
     9721 tataggtcca tttgtatatt tatacattat agaccttatt ggcccttcta ttggctctgt
     9781 aagattttcc aaaatatcaa aaattttact ttgtcttcca tttggaaacc aagtcatcaa
     9841 gctttttata actatcatcc atgctattat atctaaaaga taataaagtg caattcttat
     9901 tgttcccata tattaaccgc ctttttacta tttattttgc caagggaaga atgctttact
     9961 ttctaattct tttttcatat ttgcatctat atccacatta ttaggagcta gtataaatat
    10021 tgatttagaa accttttgta tacttccatc taagacataa actgccccat tcataaagtt
    10081 aaatatagat ttacgaactt cagaattagt caatccttcc aaattcacta taactgccct
    10141 tctttgtttt agatggtctg ctatagttgc agcttcatca taaaccttag gttcaactat
    10201 tacaactttc atttggctag ttgtatgtaa atttacaatt ttatttgctt ttgcagtact
    10261 aaagccactg ttcatttctt cttcttgaac tatatcgtcc atgccacttt catattcatc
    10321 ttcaatgtaa tcttcttctt catcaactat ccaattctta aatttagata ttattccatt
    10381 tgacattatt aacttcctcc ttaaaattta ttcaaatttg agtaattatt ttttattgta
    10441 gtttctttct ccaaagattg atgttccaac tctaacaatg gtagcccctt cctctatagc
    10501 aatttcataa tcgtgactca ttcccattga caaaacatcc atccctacat tagggatgtt
    10561 tagttctttt atttgttttg ataaatcttt aagaccttta aatacacctc ttatctcatc
    10621 ttcatcttct ataaaaggtg ccattgtcat tagacccttt atttttatat ttttatattt
    10681 ttctgacact tctttgacaa agtctacaac ttcttctcta tcaagtccat gcttagactc
    10741 ttctttagat atattcactt gtactaagca atctatttct ctgtttattt gttctgcacg
    10801 tttttgaatt tcttcgcata atgcaattct atctaaagag tgtatcatac aaactttatc
    10861 gattatgtac ttaactttat tggtttgcaa agttcctatc aggtgccagt ttaatttatc
    10921 acctataata tcatactttc tagctaattc ttggggttta ttttcaccaa cagaagtgat
    10981 tccttccctc attgcctcat taactaagtc tacatcaaca gtctttgtga ctgccaaaag
    11041 ggtaatctct ttgctgtctc tatctacttt ttttgcagct ttatcaattt tgtttcttat
    11101 ctcagacaaa ttgtctttaa tagaacccat tattatcacc tactttatcc ttatatttgt
    11161 gtttatactg ttaggtctta aaattatttt gtcatataga ttaacacttg taactccatt
    11221 tatgtcattt ttataataat ccacaaatac agaagattca ttctcataag ttattccttc
    11281 taatatgaca aattttacac tttgtgattg ttcatcaatt acatatacac cacgtttatt
    11341 gtcttttgtt tttatagaag ttttaggtat ttttaaacat tccatctgat tatatattat
    11401 atcaaattct tcgacacttg tatcctgatt tgcaacaatt tggttactta tttttaattt
    11461 taccattatt ttattattat tttcatatat tttgtaaact tttgcatcta atttttgctc
    11521 atgatattca attattacat tttgattttt ttcaaagtta ttagaatctt ctttactgat
    11581 gtatgtagat agataattac tctggtcatt ggcatctttt tctatagttc cttttacatg
    11641 aatctttgca tcaacttttt cattttttaa caccaacgta tctacatttt tgctaattat
    11701 cattactaat atattaaata ctaaatatat aagaatacca agtatcacta atctggtata
    11761 ttttaccttt ttcaaagact ctccccctat aaaattactt tcattataag tacttcttct
    11821 aaaaaatgtt tattcctttt ttataagcta atattttacg ttctaataat tattttttcc
    11881 atattaaatt tattttttat caatcttcct atacaagact gcattattta tatataattg
    11941 tattataaag tataagttta atttacattt tatacgttaa gcttacttta tatgttttta
    12001 tagttatttt tatttttaga tgcaatataa aaccaattaa gatttaaaat aacttttgtt
    12061 atgttgacat ttatttaggt aatcatttat gaattaggat aacgttatca taacaaaagt
    12121 ttatgtccta aaaaaaatac aaggaggatt ttcttatgtc agaaatttta ttaggaacag
    12181 gtttactttt attggttcta tgttgtttca caatttttag ttacaaggcc ccatatggta
    12241 tgaaggctat gggagctcta gcaaacgctg catgtgctac tttcttagta gaggcattca
    12301 acctttcttt acttggtgat gttttaggta tggaattttt tagaagtgtt ggagctgcta
    12361 atggtagtct tggtggagtt gctgctgcta tacttgtgcc tttagcctta ggtgtatctc
    12421 cagtttatgc agttttaata ggattatctt gtttagattt ttctatatta tctggattcg
    12481 ttgctggata ctttgtttct ttcttaatta agtttataga gaaaaaagtg ccacctggag
    12541 tggatttagt ggttgtaatt cttctatgtg caccgctatc tcgtcttata gcatcaaatg
    12601 tagacccatt agttaatagt acactactac aaattggaca agttttgata gaagctacca
    12661 acattagccc tataataatg ggaattatac taggaggtct aataacagta gttggaacgt
    12721 ctccacttag ttcaatggct cttacatcta taattggtct tactggtctt cctatggcaa
    12781 taggagcatt aggtgctttt ggttcagctt ttatgaactc aacactattt gcaaaattga
    12841 aattaggttc taaaaaagat attatatctg ttgctattga accattaacc caatcagaca
    12901 taatttcagc taatccaata cctatatatt ctactaattt ctttggagga gccttttctg
    12961 gtatcattgt agccttgatg ggtcttgtaa acatgacacc aggtacagct acacctgtgg
    13021 ctggttttgc tataatgttt gcttataatc cagttcaaca agttcttata acagctggtt
    13081 tatgtgcttt attcaatgta attgcaggat ttttaggttc aaaaatattc agtaccttta
    13141 aagttcttac tgctggtgaa atacgtggta ctgatgtaga agaagaaatt gcttaaaaaa
    13201 caataagatt tataaattta tatctcaagt agtagagttt tatattgtag gcaattttat
    13261 taattgcaaa cgttttattt tttatttatg tttatgatta ttatgtgtgt tgaatattta
    13321 gataaatttt tatttattat ttttatttag atttttgttt agttttttat ttggttgata
    13381 tattaggaat aaaaattagt atagtttatt actagttaga tagcataact ttttagatac
    13441 ataaaaaatt ttatattaat tagatattat taaaataaaa gcgatacatg aatttttaaa
    13501 tgtccatgta tcgctttatt tttgccataa tcttaacaac tgatttttaa agtttattat
    13561 cttaacaaag ttcattatct tatataatat ttaaatgcat agacttcttt aatttaacca
    13621 tctaaatatt taattaaata ttattatatg taatataact aatttttaaa tgaatgtata
    13681 ggagctggaa tccttcctcc tctttgagta aataattcag atgaatttgt atttataggc
    13741 attactggtg ctcgtcctaa aagtcctcca aattctacca tatcacctac atcacatcct
    13801 ggggctggta taattctaac ggctgtagtc ttattattaa tcatacctat tgctgcctca
    13861 tcagctatca tggctccaag cgtacctgct gtagtatttc ctggcacagc tatcatatca
    13921 agacctacag aacaaatagc agtcattgct tcaagcttat ctatacttaa agcaccttta
    13981 ataacagcat caatcatacc tgcatcttca gatactggta taaacgctcc actaagtcct
    14041 ccaacatgtg aacatgccat tactccacct tttttaacag catcatttaa aagtgctaat
    14101 gctgctgtag tcccatgagt accaacaact tcaagaccca tttcctctaa tatatttgct
    14161 accgaatcac caatagcagg tgtaggagct agtgataagt ctattatccc aaatggaaca
    14221 tccaatctac tagaagcttc ctttgccaca agttgtccaa ctcttgtaat tttaaatgca
    14281 gtctttttaa ctgtttctga aacaacatca aaaggctctc cctttacttt ctctaaagct
    14341 ctcttaacaa caccagggcc acttacacca acatttataa ttctatcagc ctcaccaaca
    14401 ccatggaaag ctcctgccat aaatggatta tcttctactg cattacaaaa tactactaat
    14461 tttgcacaac caaaaccttt tgcatctttt gttaattctg cagtttcttt tatgatttct
    14521 cccatttctt tcactgcatc catatttata ccacatcttg tagaacctac atttactgaa
    14581 gcacatactt tattagtact tgctagagct tttggaattg acttaattag tatcttatca
    14641 ccttttgtat atcccttttg aactaatgct gagaatccac caataaaatc tatacctaaa
    14701 tcttctgcag ccttatccaa tgtctgtgca aactttacat agtcattttc atctgttgca
    14761 cctgcaataa tggaaattgg agttactgat acccttttat ttacaattgg gataccaaat
    14821 tcacgctcta tatcttttcc aaccttcacc aaatctttag cagaactcat aatcttattg
    14881 tatatttttt ctctagcttt atctccatca gggtctatac aatctaataa agaaatcccc
    14941 atagttatag ttcttatatc caactgttct tcatctatca tctttattgt ttcaagtata
    15001 tttcctacat tcactattat cacctcccct tactgtctac tacagattat gcattgaatt
    15061 aaatatttct tctcgctgaa tttttacatc cactgataat ttcttacctc tttcaaccaa
    15121 gtcctcaacc gttttctcaa aagaatttaa tgatttctct aaatcaacta tcataatcat
    15181 agtaaaataa tcctgtaata ttttttgtga tatatctact atgttgatat tttgcttgta
    15241 taattcatca ctaattcctg ccactatacc tggtttatcc tttccaatta ctgttaaaat
    15301 tgctttcata ataatatcct cccttatttt tttataaatc ttatattttt acaaattgaa
    15361 ctatgtgtta acatatattt catttatttg ttagtaaacc actttttatg tatatattta
    15421 atatatttta atacctatac attcatttgt caattttttt tcaatattct attattttta
    15481 tactatttag aaaattcata tattatatat gttttctcaa caacaaatac agttttcata
    15541 ataatgaaag gtattactta gcaatctcat gattttctaa ataatacctt tctaaaaatt
    15601 atttttttaa ttttatgaat ttaattatac tttttctagt atcaggattt acaattaata
    15661 tagaaccaat cataattggt gttagtatac aaaataaaaa aataatatct ttttttagat
    15721 tatattcttt agattctaat ttataattat tatttattat tccatcataa tcacttatat
    15781 ttgacttatt tttatttgta tcttgatttt tgttagaaat actttcccta taaggaaaag
    15841 aatgttcatt ggtaccaaat actgattttg agcttaaatc ataattatca tcattttctg
    15901 taattgaatt tttattgtaa aatccttttt ctttatcaga attattttct ttattaccgt
    15961 ctttaggtat atcatgagga tttttatttt cattgctatc agtacttgat tctacatcat
    16021 ctttaggagt atttggttgt ttctcatcag aattatcatt ttcattatta ttattttcat
    16081 tattattgtt ttgattgtta ttactatcat tattttcatt tccattattc ccatcttgat
    16141 tgttatcatc ctcatctcta tccgggtcgt ctctacctcc tcctccacgg tcaccatcaa
    16201 tatcatcatt ttcccgttca tcatctggcg tctcttgatt gtctccgcct cccattataa
    16261 atcctggttt aaaaactata tttgaatacc cttcttttaa tcctcctacc acttttactc
    16321 taaaacaacg caacttaaaa tcttcaaaaa aaagtatagc ttgatctcta atatcctcct
    16381 gttcttcaga tatccaattg attccatcgc ttgaatattc aacaaaaacc ttacttgcac
    16441 tatacggcat atcataaaat aaaacagcta catatccatt ttttgtattt tgaaattcca
    16501 gttccaaatt gtctattggt tttttctcta taacagatac attcaaaata ggaactacat
    16561 catcatttat tataattttt tctttattta acatttctgt tttaaacttt cctgttatat
    16621 taaaattttc tcccttttcc aacttttcat aataatcagt aaaatcccat tctacatcta
    16681 tatcaagtcg attaccacta gatgtttcta ataccatata tttgggaaat tttatatttt
    16741 ctattttatc atctttactt acttttattt catcactaaa tacaccaatt cccctatgac
    16801 aacatttcac aatatcatag ccagaatctt cagctataga aggtataagc tcattataat
    16861 catcaattat ataaactttc ttactttctg atataattga ttgtgccaac ttattattat
    16921 ctcttagtaa cccactttca ttgttgctac tatatgcttt tattgaagtt tcttctatct
    16981 caacatcacc tttagaataa acacctatag catgttctcc attcacttca atatccttat
    17041 ttagtattct aatatcattt tcagtataaa ttcctattgc atcttttcca tttgccttta
    17101 ttttttcaac agattcgtag gatgatttaa tatgtaagtc tcctccttct tcaacgtata
    17161 aggctgtccc atcagtagca attatgttgt ttataccaat acttatactt ccaccatttt
    17221 ctatatgtat tactccttct tttcctcctt cacctattat attcaattca ttatcatcaa
    17281 taataaatct cccatgattt tttatcaata ttttatattt gttggtatct attgtaaaat
    17341 tactgtcata aggaatataa aatctaaact cttcatctat taccatatca caagaaagag
    17401 tataaactat ttcttcttta ttatttttat tttcttgaac ccacctttca aaatcttcaa
    17461 gacaattttc ctcttgtcca aaaactttat gtggaaaact tataaaacac aaaactatta
    17521 tactcataaa aataaatatc tcatactttt tcatcttaca ctcctagaaa tttttagctt
    17581 tgaaacaatc ctgtcgaaac atatacttca cccactataa tttttccaca attatcaatt
    17641 attgtcaatt tatataagta tctttattaa ttgttataaa taaaaagcta cttactaaag
    17701 caaacagacg tttcacttta ataagtagct atatttttat aacaaaatag ttataatatt
    17761 agaacttcct tcatttacaa ttttttgtaa agtcttttgc attttaactc ttatctcttc
    17821 tggcatagta tataatttac tttgtaattg ctcttttact aagtcatgta gtgatttacc
    17881 aaacatattt gattcccata aatctgctgg ttgctcttca aatacttcca taagatattt
    17941 tatcatctct tcaccttgat tttgatttcc aactattgga gaaacctctg tagatatatc
    18001 tgcttttata atatgaagtg atggtgcatt ggcttttaac ttgataccat attgttttcc
    18061 ttgtttcatt atttctggtt cttccagact aagttcttct aaggaaggag ctactactcc
    18121 atatcctttt atcttggcat ctattaaagc actttctatt ttatcatact catttttaac
    18181 tttagatagt ctagttatca gactaagcag ttgataatct ccttcaattt taaatccact
    18241 tttttcttca aggacattat agaataaatc ttgctttgtc tgtaaatcaa tatttataac
    18301 accttctcct agctctacat tatcaacacc tgtatcttcc aaaaactcta actcagaaaa
    18361 tccttgtata ataccttcta tatcccttat tttacctata tctataatac tttgttttaa
    18421 tgttgttatt atgctacttt ttatccaatg atttctttca agaccttcaa cccattttgg
    18481 taagttgatt cttatttctg taagtggaaa atcatataat acagcttcca taacctcctc
    18541 tatatcttct tcttccattt caaccacatt cattggaaga actggaactt catacttttc
    18601 ttccaattca cttctaagca tactcgtttc ctcacttttt ggacttaacg tatttaaaac
    18661 cactgcaaat ggttttttaa gatttttcaa ttcttgtata actctctctt ctggttctac
    18721 atagcttttt ctgtcaattc cagtaactga accatctgtc aagacaacta tccctattgt
    18781 agaatggtct tttataactt ttttagttcc tatctctgct gccttttcaa atgtcatagc
    18841 ttcttgtgac caaggagtgg atactaatct ttgttttcca ccttcctcat gccctaaagc
    18901 tccttcaact atgtatccaa cacaatctac cattcttact tttaaagata ctgtgtcttt
    18961 tatttttatt tctacaccat ctgctggtac aaattttggt tccactgtca ttatcgtttt
    19021 acctgaacca ctttggggta tctcatctct tgttctatcc tttttaaatt cattgtctat
    19081 attaggtata accaactttt ccataaattt tcttataaaa gttgattttc ctgttcttac
    19141 aggtccaact actccaatat atatatcccc ctgagtcctt ttggatatat cttcgtatat
    19201 gttattattc atattattcc tcctatacat ctaatcttat taaattatat ttagagttaa
    19261 gggttaatat tcttaaaata gaaaaataaa gaccagcaat attaatttaa tttacatata
    19321 gaaatttgta aatttcaatg taaattaaat taatattgct ggtccaaata gtagtgtatt
    19381 atattaactg actttagtag tattttcatt tgaattatta ttcatctcaa taagttcttt
    19441 acgtctttct tttgtcatgt tcatccatat aaatgtaaac accaatccaa ttatggctac
    19501 tatagtaaga actatgaagt agtacctata tccagttaca cccggaaatg catccaatat
    19561 cttccctgct gctaaaggac aaagtacttc tggaagatat cctaatgtag caactattcc
    19621 tatagcagtt cctgatattg ataatgaata attaccttct tcaagtaacg aatagtgtaa
    19681 accttgaatt gcatacatag atacatatat tgcaacacat ccaatcaata gtatataaat
    19741 catagatgat tttgttggtg taaatattac acctaaaaga cctgcaatca taagtataaa
    19801 tccataagat ataatctttg atgaaccaac tttatctcca agtaatccag aagcagctga
    19861 tgctactggt ctacaatact gagctaatat tgagattgca gatgcaaaca ccacagtagc
    19921 tccaaatgct tcagttgaat aaggcgtaaa ataataaaat gacatattag ctgaatatga
    19981 acaaaacatt attattgtta ttatccatgt atgaggcatt tttattactg caaaaaaggc
    20041 ttctttatca aattttgctg atacctcttt ttcattatcc tttaatttga aaaatactaa
    20101 tactccaact attacattta ttgccgagta taatactata atagctgtaa gaccagattt
    20161 atcacttact tttgatgaaa tatacccaaa tagtatcaat actagagata gatgaattgc
    20221 attggtaatt ccacgaccac tttccataaa tccaaaagct tttccttgtt cattttcaga
    20281 tgctaacatt ctaacagctt ttacaagagc tggccaaaaa gtaagtattg ttgttattcc
    20341 ccataaggca tggattaaaa acacaacaat atatggagga taaagtgtta atacaagacc
    20401 agatattcct gtaataatta aagaacctga aagcaatttt ctggctgaaa tacggtctgc
    20461 taaaaaacca ccaaaaaggt atgataccat tgcaagtaga ccataaatac ttcctaagct
    20521 tcccatttgt gtatttgtaa gattaaatgc ttgtgcaaaa gtatcataat aataattctt
    20581 taaatatggt aaagcatata taaatgctcc tgctacaaag agtattatca agactttgaa
    20641 atttttccaa atgcttggtt tatttacttc aactgacata cttcctcctt atgtaaatac
    20701 ctgtaaattt tcatgataat taattattgc ttattgtatt gtttattcaa tatttcggaa
    20761 tatttattaa tatattaggt taatctatca ataatttatg gtgagttatg agctaaaagt
    20821 aaactctttt agctcaccat aataattata tttttattta tactaacgtc cagagttatt
    20881 agatatcttt ttttcatagt tcttccatag cattaaacct gttattataa caaaaagacc
    20941 tcctcctatc atttcaatct catagattat attatctttt aaagtctcca taactggtgc
    21001 cgttgagaaa agtatgccaa ctacagttac tacaagtacc attctggcaa tattgataca
    21061 aactgaatca ctttttgcaa ttgaatatgg tctttcttca tttggtcttg tctttctaag
    21121 tctaatataa gatgtaaaaa gcaagacata tggaaataat gctgttaatg ctgtcatagt
    21181 aacaagaaca ttgtatatat tatctactga tggtaataag tttgttccta caagaagtag
    21241 actcactatt atagcctgaa ctattactgc atttgatggt atattgtatt tatttgtaac
    21301 agtcaattgc ttaggaaata caccttctct tacatttcca aaaagcatct ttactggacc
    21361 tgctatataa agtattaatg ctcctagtac tgataaagtt attccaaatg ctactattct
    21421 tataaaccaa cttcctatac ctaaatcttg tgcaacttta gctaatgcat ctagtatccc
    21481 tgtagatgct gcaattttat ctggaggaag tatcattgtt attgctactg aacctaagat
    21541 atagattcct cctattaaaa cagccacagt taatatagct ttaggaaagt ttttcttagc
    21601 attatccatt tcggttatga aattagcagt cgtttcagct cctgataatg caaatattat
    21661 agcagatata gaaactaatg aattggcatc tatttttggt attatatttt ggattgtata
    21721 tatcgatgct gatggagctt ttttgagaat aactacagac ataaatgcca tcactataag
    21781 taatatagca ggaattgtag aacctaatgc tcctgtattc gtaaaaaatt ttccaaatgc
    21841 catcccacga gtacttacta aggacaacag ccaaaatatt atgagtgaaa gtgctaaaat
    21901 aaacatctta ttgtttgata aatctggatt tccaagcata tatgcaatat ttatagctaa
    21961 aaatgtcaag aaagaagaat accaaaatat ctttgatgtc caatttagcc atgacaccat
    22021 aaatccccac ttctctccat aagcttgttt aacccattct ccaagtccac catcttttgg
    22081 atatgttgca gccaactctg cacatataag tgatgcagga acaaagaata taaaagcaaa
    22141 caataaccaa actggtatag aaccaagacc caatccaaaa ctagaggcag tagatttagc
    22201 tatccatcta atcccaaata gtgctgatat attcataaat actaaatccc aaaatccaat
    22261 tttctttttc actgtaattc ctccaatttc aaatttattc aaactcatac actatgtatt
    22321 gatttaaata tcaagtataa gttcttcaac acttcttgga taattagtta taattgtagc
    22381 accattctta cctactattg ctgtatctga gtgtctaaat cctccaactc caggtatata
    22441 tatccctggt tccatagaaa ataccattcc ttcttctaat attaattcat tgtcaaatct
    22501 taaatatggc tcttcatgtt ctgacaaacc taaaccatga ccaattctat gatttgaata
    22561 taactctaga ccatactttg caacaacagc tcttgctgct tcatccacca ttcttgctgg
    22621 tataccagct tttattgtat ctaatccagc ttgttgagcc tctactgcaa tcttaaacac
    22681 ttctttttgt ctttctgttg gtttgcctat aataaaagtt ctttcatttt ctgctctata
    22741 gttttcatac caaacctgtc tactatgtat tactatatct cctctttgaa gtattctagt
    22801 attagaatct aaatgaggtt gtgctgttct atcaatccct gaacaagtcc agtttgcaaa
    22861 tcctatatat gtatcaggat aattttcaga aacatatttt agtaaagcat tatccccttc
    22921 aacgtcaaac tccaattcac tcatcccaac tctaacattt tctaaagacc cttttattcc
    22981 tatatcagat aggtaacctg ctatcttcaa aaattctatt tcttttgcat cttttacata
    23041 tctcatttca aatattttac ttccaacatc tttgatagca aatgacttat cagttatata
    23101 ctctgaaaag cttgcagata ctatatcttt ttctattcca acagttgttc ctttagggta
    23161 tttatttaaa attatatcta agtaatgttt atgtgatatt ccatgttctt tcatttctgg
    23221 tatttcataa tacacatata cattatcaac ttttgcaact tctttagcat gtaattcttc
    23281 taatccaggt actattaatt ctattttatc ttgagttact actgttacaa ttggtctaga
    23341 ataagttatt gctttaaatc cactaatata aaattgattg tctggttcaa atattaaagc
    23401 aatttcaatg cttttttcat tcatgtactt tctcaatctt tctagtctca tattatttga
    23461 cataatgcac ctctttctta atattcagat aatttattca atacaacaag gatgaatata
    23521 ttattttaaa attcttaata tttttagtac ttgtcgtatt tgtatgtaaa ttaattttat
    23581 ttgtgattat tttatcataa tcatgattat tttgtcaatc atgattttat tttaaaaaat
    23641 tttttatatt ctagtgattt taaattatct aaaatataac gagtatacat tgtattttgt
    23701 aatattattc ttgatttatg gtaagtttaa tgataaaatc acgattatat aaactatatt
    23761 gattatttgt aggtgaataa aatgacaaat aaagaattac aaaagaaaag gatattgatg
    23821 tatttcatag aagctgctca aaatattatg gaaaacgaag gtatagaaaa tattacactt
    23881 cgtaaggttg cagatatggc tggctataat agttcaactc tatataaata ctttaaaaat
    23941 ttagaccatt taatatcatt tgcatctata aaatatttta aagattataa cttgaatatt
    24001 tcaagatgta tagaaaatgt caatgatgaa tataagaaat atataattat gtggaaatta
    24061 ttttgtaagc attcttttga taatgctcaa gctttttacc aggtattttt taacttgtct
    24121 agtgatgaac ttagctatat aacaaaacaa tattatgata tgtttccaga agatttaggt
    24181 attcatgata gtgacatatc tttaatgatt acaggagaaa gtataaagga aagaaataag
    24241 atactattaa acaatcttgt agatactgga tatataccag ctaaagattt agacataatc
    24301 aatgatataa ttatttcttt ttatcaaaat ctattattct taaaaaagaa cacaggaaaa
    24361 aattctgatg atgatgaatt aactatgaaa atgatttctt ctattgaata cataataaaa
    24421 catgctaaat aaaattaaaa tatggctgtc tcaaaataga gataagcctt ttttattgtt
    24481 gaaataataa aaatatattt aatttcatat aaaaatgagt gcctcgtaaa ctaaaaagtt
    24541 cattttgaga cacccctaaa ataaatttat tatttattat acaatagttt atatatcatc
    24601 acctaaaact acttcttcca tttcatgctt tttacttctc atcattagtt ctattccaac
    24661 ttctttagga tttgaacctt tctttattac agaatatata gcattagtta taggcatatc
    24721 tatatctaat ttttcagcaa catcatgtgc tacttcagta gcagttatgc cttctacaac
    24781 catctttact tcttttaaag tatcttctaa actcatccct ttacctatga gtataccagc
    24841 tcttctattt ctactatgca tacttgtaca agtaactatt aaatctccaa tacctgaaag
    24901 acctgcaaag gtagacatat tagctcccat agcaattcca agtctgctca tttcactaat
    24961 acctcttgtc ataagggcag cttttgcatt atcaccatac cctaatccgt cacatatccc
    25021 agctccaaat gctataatat tttttaatgc tcctccaagt tctactccaa ctatgtctgg
    25081 attcgtataa actctaagtt tagggctcat aaacaaatct tgtatcatct gtgctatttt
    25141 taaatcttta gaagcaacta ctacggtagt aggaatatcc cttgctactt cttcagcatg
    25201 agatggccca gatagtatta catatggatt ttgtggtaat tcttcttcac agacttgtga
    25261 taatctaagc ccagtccctt tttcaagacc tttagctaca ttaacaataa cttgtccttc
    25321 ttttataaat ggttttattt tttggcaagt acttcttaca gcctgtgatg gaactgctaa
    25381 aactattacc ttacaatctt ttatagtttt ttctatatca gtacttatag ttatattatt
    25441 tggaaataat actcctggta aatagtctgt attttcttta gttctgttta tttttttagc
    25501 ttgttcctct tttcgagtcc acatgctcac atcattacct ttttttgcaa gccctaaagc
    25561 taatgcactt ccccagcttc cagtacctaa tacacatact ttctccatgt ttaacaccac
    25621 ctgagtataa tatatttact attctttctt ttgaccaatt tttctctctg tcccatttaa
    25681 taatcgcttt atatttgctc tgtgattata tattactgat gcagttaaga acagagctac
    25741 tattaaacca gctttatttt ttaccataat cataaatatt ggtgaacatc ctattcctac
    25801 aacagaaccc aatgaaacat actttgttat agctaccacc aatataaata ctgctagaca
    25861 cattagtgtt attactggat ttacagctag cattgcccct agtgaagttg caacaccttt
    25921 gcctcctcta aatcctaaaa ccgctggcca attatgacct gctacaacac atataactgc
    25981 cagatatcca gctaaaagag tatctattcc aaccaatctt gctgcaaatt ctgatattaa
    26041 aacagccatt acacctttaa gaacatcacc taaaaatgtc attgctcctg ctctttttcc
    26101 aagtgtccta agtacatttg tcgaacctgc attaccagaa ccttgagtcc ttatatcaac
    26161 cccagcaatt cgctttgcaa ctatgtatga ggtagatata tttcctaaaa gatatgcaac
    26221 tacagcaata attatataac taaatatctc cactgaattt ccccccttta gttatatttt
    26281 aagatattta ttttttattt ttttgtctat actcaaactt tatggaagtt ccttcaaatc
    26341 caaaattttc tcttatctta ttctcaaggt atctttgata tgagaagtga gttaaatcct
    26401 tatcatttat aaacaatgta attttaggag gtctaatgtc agtttgagtc ccatagtaaa
    26461 tttttaatct tctacctttg tcagatggtg gttgatttaa cattacagct tctccaatta
    26521 cttcattcag tgctgaagtt gatattctct tagaatgttc atttgacaca tattcaactg
    26581 tatctagtat cttgttcatt ctttgattag tttttgcaga aacaaatacg attggagcat
    26641 acatcataaa tggaaatttt tcttttatat cttttgtgta attactcata gtcttattat
    26701 ctttctctat taaatcccat ttattgatta caaatatgca tccttttcct tcatcatgtg
    26761 ctatacctgc aacctttgta tcttgttctg ttacaccttc taaggcatct attactatca
    26821 atactacatc tgctctatct acagcactca tagctcttat tacactgtat ttttctattg
    26881 tctcatatat tttacttttt cttctaagcc ctgctgtatc tattagaaga aatttctgtc
    26941 catttttttc aaaataagta tcaattgcgt ctctagtagt tcctgcaatt ggacttacaa
    27001 ttactctttc ttctccaagt atcttattga gtatagaact ttttcctgca tttggtttac
    27061 ctgttatagc tactcttatt atatcttctt catactctgt atctaatcct gctggaaaat
    27121 tttcaactat ctcatctaat aaatctccaa atcccatact attggctcct gaaactgcaa
    27181 aaggcgttcc aaatcccaac tcataaaaat cgtatatatt atcaaattga ctttgactat
    27241 caatcttatt aaccactaag attactggtt tttttgtctt tctaagcaat tgtgcaattt
    27301 ctttatcagc agctgttatt ccagctttac catcaactat aaaaagtatt acatgtgaca
    27361 tgtccattgc aagcatggct tgatttctca tttgagataa tattatatct tcgctatcag
    27421 gttcaattcc tcctgtatcc actaatgtaa aatatttatc taaccattct acttcagcaa
    27481 atattctatc tcttgtaact ccaggtgtat tttcaactat tgatatcctt tttcctgcaa
    27541 atttattaaa tattgtagac ttaccaacgt ttggtctccc aactacagct acaactggcc
    27601 tacttatact cattttattt ctccttccat cttttgtttt ctattttaaa attttatcca
    27661 caaaatcttt tccttcattc aaacaaggga taatttttat tctcataagt tcttctaatt
    27721 gatttaattc aatattatct aagaaaattt cttcatctgc ttttagcata cttcttgtta
    27781 tataaagagc ttctcctaat tctttatctt caagttgttc ttttaaatcc ttagctgtta
    27841 aaagacctga tacagttatt gtctctccaa aaaacttgtt tttgatttca tatacattta
    27901 cttgaagatt tttaaacttg tccatcatag catctgccat actctgtata aattcatatg
    27961 cagaatgacc agtagctatt gatactttct tctctctttt tagaatcttc tcaggcaata
    28021 tatttagata ctcttcaatc tctgttttta acttacgtat catacctaca ccatcttcaa
    28081 actgtaaaaa accttcatat tcttcatatc caggcaattc actattagat agtatataaa
    28141 attcatctga taaaaatgca aatcgagtac ctaatttttc aagatatttc tgttgtattt
    28201 gatgtatttg ctctatagtt ttacttgcgc tcttatcatt aaatatattt aattctacta
    28261 gattttctct atgctttgta atcccaactg gaactatcgc aacactgttt acatacggat
    28321 aaagttgagc tagttctttt attgttctat ccaattcctt tccatcattt atacctggac
    28381 ataaaacaat ttgacagttc atttctatat gagtatctgc caatctcttc attataccat
    28441 ataattttcc tgcaaattta ttgcttatca ttttttgtct taactctgga ttagttgtat
    28501 gcacagatat atttatagga cttattctat attttataat attatttata tcttcttcac
    28561 tcatatttgt aagtgtgaca aaatttcctt gtaaaaaaga taatctcgaa tcatcatctt
    28621 taaaataaag agtttctctc ataccttctg gcaattggtc tataaaacaa aacatacact
    28681 tatttctaca gcttttagct tggtcaatta tcggatttgt aaattcaaca cccaaatctt
    28741 catcatagtc tttttctatc tcgtatatgt agacttcgcc atcttttttt tgtatttcta
    28801 catctaaata ttcatcactt agtaagaatc tatactctat tatatcatgt attggctgtt
    28861 cattcacaga tataagtaaa tctcctacct ctatacctat ttcttctgca atactatctt
    28921 tataaacctt acttataata ttatttactt tttttacatt tacttccaat attttcacca
    28981 ctcttttgta ttcatcaatg cttattataa tatattttaa tatgcaattt atttatttat
    29041 tatattttat gatagcattt ttaagcattt catgtcataa taacacattt taattctaat
    29101 agtcaatata agtaaatagc tataaaatag attagaacaa ataatattca aatttaagtt
    29161 tcttaaaaat ttgaatatta tttgttctta aaaaaatttt ataaatttaa tgttttacta
    29221 tgattaacgt cccatttgtc atatcatgaa ccattccacc tacacacttt gacatcaaca
    29281 atgccttatt ttgtaagtct ttctcatcat ttgcataaaa tattggacaa cctccaccat
    29341 ttttcatatt cttatcaagt gtaactatag ctagggtata ttcatttaaa cctatatcca
    29401 ttcccatctt atgcacttcc tttctttcct attttataat tttttagtga taagtttttt
    29461 cctttagaac ttgaaagtat tgggcatgac tttacggctt ccattacttt ttccacattc
    29521 ttatctactg gtaaataagc aatcattata ctttcatcct ctttattcct tctaggtaat
    29581 ggtacgaatg aaggttctcc ataatctcca tataaaccta accttgaata tatattgtat
    29641 actattgcct gtctttgacc tgagtcaaat aatatccctg cattagcata atctttattt
    29701 ttaggaatta tttgtattcc tacacctcta ttaatatata cttctctatc actttttaga
    29761 cctatatttg ttattccctt taaatctcct accttcaata tagactcatc tacaaaacta
    29821 atctcagcag gcattacatc agctatgtct ccaatacttt ttctagtaag aagttttttt
    29881 aatataaagg ctaacactaa tccacaaatt gaacttatta ccaaactcat tccttcactt
    29941 attttcgttt ctgcaagtat tacataatac aatcctattg ttaaaaaaga tgtaactata
    30001 cacatataat ttcttacttc ataggttcta gctatctctt ctatgaatgc agctcctctc
    30061 tttacaagtt gaacttcctc taagttttgc aatgtatttc ttctatttgc tctcacttgt
    30121 ctaaattgct ctgctgctag ggataaaaaa gttatagatg tataagaacg atttataaga
    30181 gctggaacca ataatgctcc taatgaagaa gcgacgaatg ctaatataag ttgagatagt
    30241 aaaacatttg gttgcgttgg atactgtttt tggtctaaat tcaacattat aattctagat
    30301 gttataccaa taataacagc aacaaaaaat actctatcca ttaaatcact cctaaaatat
    30361 ttaatttgaa attttacatg taaatctaca aagtctttct agaaaaatca ctctgctttc
    30421 cttttgatgt ttctatgata ggtgtacttt tcactacatc tatcatgaca tctatatctt
    30481 tgagtattgg catatatggt ataaccacag tacttttttc taaattggtc ttagatatag
    30541 caacaatatc aacctcatct acatctctat ctatccccat atgaataaat agattatgta
    30601 ttatagcttg tctttgccct atatcattta ctattccaaa tgcacctaaa tctcttggta
    30661 taacttctat ggccagacat tcatttctat acttttctct tgtactttct agacctatgt
    30721 tagttattat tacaccattt accattaaaa taggtccttc aaaacttatt tttgcaggaa
    30781 ctatatctgc tatatctgct atactgttcc ttcttaaaaa tcttctaaaa atcaaaccaa
    30841 caatagctcc tgacacaata gctaggattg tgcaataaaa aaagctaagg ccatactttc
    30901 ttgcaaaaac gatataaact atcgaagata ccagtgcaga aaaaagactt atataacttc
    30961 tagattcata cgtagatgct atttcttcaa cgtaagcgtc tccttttggt actaattctt
    31021 cattatcgat attctttagt gttattcttt cttgttctgc aagaccttga aactgttgta
    31081 ttgctactgc aaaaaatgtc aaggctgcaa actccttatc tataagtgca ggtaatgcta
    31141 tagcacctaa cgaagctgaa agcccagata taattatctg ttctaaataa tcttgtggtc
    31201 ttgatgggta ttgtttgtct gtaactctta aaactaatcc tctacataat attcctacaa
    31261 ctaatgcaac tataaaagag tgtctaaata aatttgcatt caataaactt tcttccattt
    31321 tctcagctcc ttctcttata tagtttgtgc aaaaaacaaa aaaaattccc ttctatttaa
    31381 ggaaattttt ttgtaatatt gtaactataa attcgctacc aatgccaagt tcacttttta
    31441 cttttataca tccatttagt gatttgacta tatgctttgt tatagccaat cctaaacccg
    31501 ttcctcctac atccctactt cttgctttat ctaccctata aaatcgttca aatatgcgtt
    31561 ctacatcttc ttttggtatc cctacaccat tgtctataac tttaattacg attttttctt
    31621 catcttttaa cactacaact tgtacaatcc cattatcttg ggtatacttt atagcattat
    31681 caactaggtt taagaacact tgctttatat agtctttatt ggatagtata cttattgatt
    31741 tatcatcaca tttatataaa acttctatat ttttttcact agctgaatgt tgagttattt
    31801 catatacctc tttaaataca tcatatacta caacattttc cataagaaga gtatctttat
    31861 tttctacaaa tgataacagc aatatatcat caatcaacct ttttaatcta tctgattcgc
    31921 tttctattat ttctaagaat ctatttctag tattcacatc tatattttca tttgacttta
    31981 gtgtttcaac aaacccactt atagatgtaa gtggtgtttt aagttcatga cttacatttg
    32041 caacaaaatc acttctcata ttttcaagtt taactttttt agtaatatct tctatattta
    32101 ctatcgaacc tattattacg ttgttagtat tctgaagata aactgggtct acttttatct
    32161 tatatacgat atcatcttta gtagtaatat tagcagtttc attatcttta gaaccaataa
    32221 attgaagtat ttgttttaat atttcttctt cttttattac aacattaata ttatgacctt
    32281 caactaattg atttggttca ctctttatca tttcttttgc ttcatcattt atcagaagta
    32341 tatttccatt tacatctata gctaaaattc catgagatat actctttaat atagacctta
    32401 gctgtaaatg tttatactgt acttcttcta aggttttatc catattcttt atcatatgat
    32461 taaaatttct agctaattcg ccaagttctc ctttggctga tatgttaagc ctagcatgat
    32521 attcattatt acttactttt tttgagacgt atataaactc ttttaaatat ttccttaatg
    32581 ttattgtgta tcttacagct aatataacaa tggctatgga caacataaca ataaaaaaat
    32641 atatactatt taaatcttcc acaagataac actcctaaaa tataaccttt ttaatctatt
    32701 ttgtatccta cacctcttat agtctctata tatttttccg atttatcttc atcttctatt
    32761 ttttttctta aatatcttat atgaacatct actgttctag tttctccata gtattcatac
    32821 ccccatattt tatccaaaag ataatttctt gaaagtactt ttcctttatt ttgaattaat
    32881 aattttaaca attcaaattc cttaagagtt aactctatct tttcagagcc tttggtaact
    32941 tcatgttttg ataaatctag ttttaaatta cctgtagtaa gtatattgtt ttcttcacct
    33001 aagctagtca aattatatct ccttaaaaca gaactaatcc tagctaacaa ctcttttata
    33061 ctaaatggct tagttatata gtcatcagca cctatttcaa gcccttcaac cttgtcattt
    33121 tccatatttt tagcagtaag cattataaca ggaatatttt ttaagtcctt atcacttctt
    33181 atttttctca aaacttctat tccacttata tttggtaaca tccaatctaa aagtattaaa
    33241 tctggtttaa tttccttagc ctttataaat ccgtcaaatc catcatatga ataactaact
    33301 tcgtaatttg acacctccaa attgaatttt aatagctcaa ctatatgcat ttcatcgtct
    33361 ataacaagca ctttagtatt cattaaaaag ctcctctcta ttttatctgt agtaccgttc
    33421 ctattcgttc tgatgcctta ttatgttttc tataagagtg gaatttatct gctctacaac
    33481 tagtgcataa atttaaattt attatatttt cttttttaac tccactacat ctaagcatat
    33541 actcattaat tttccataaa tctaaatagt aacttccctc ttttattata tagaactttt
    33601 catcattatt tgtaagaatt gtgttaaatt tttctactaa atcttcagac acttcataac
    33661 aacatggtcc aattgatggc ccaattatac atactaaatc ttcaggaact gttttatagc
    33721 attcagacat taattttatt gttttatgac ctatattact aaaagtccct ctccaacctg
    33781 catgagccag tcctatggct ttatttttag catctataat tgatataggt acacagtctg
    33841 ctgtaaacag taaaagtggt actttttcca agtttgttat aagtgcatct ccatctcttc
    33901 ttttccctat agtatcttta ttgactatat taactatatc tgaatgtatt tgagaattac
    33961 tagttagatt ttcaaatgtc aaatcacatt ctttacatac ttttaacata tcttctctat
    34021 tttttgcatc tatattctta catgttataa ctagatttac agaatttaat ttttcatcaa
    34081 gttcttcaca attaccactt aaattaacat actctttaat atcttgtaca ttttttatat
    34141 ttatataatc tttcatcatt tgtctccttt ttctatcagt atacttttaa gttcatttac
    34201 aaaagtattt atatctttaa attgtctata cacagaagca aatcttacat aggcaacctc
    34261 atctaactct ttcaatttat ccattaccat ctcaccgatt tttttggttt caatttcttc
    34321 tataaaacat ttatttattt cattttcaat atgtacaaca atactttcaa tctcgtcaat
    34381 agaaacaggt cttttttcac atgcttttag caatccatat tttatctttt ctctatcaaa
    34441 atattctcta ctattatcct ttttaatgac cattaaagga gttgtttcta ttttctcata
    34501 cgtagtaaac ctctttttac atgattcaca ctcacgtctt cttctgatag attttaaatc
    34561 tgtatgtcta gaatctatta cctttgattc tttataatta caataaggac attgcatcta
    34621 tattcctcct ttgtttaact atatctcaaa ctcatctaag cttaattctg aacctatatt
    34681 tactattatt gtatcacaac ctattttaag tatatcattc caaaatataa cttcttcatc
    34741 ccctcctctt gaaaaaaaac ttctacttcc atctccaaaa atggtaaatg agactacctt
    34801 accttcgtga atatccatgt ctatgtctat tataaacccc atcctttttc cattttttac
    34861 atttataatt tctttttcca ttatatcaga aactctaatc atattgtact caccctttct
    34921 ttaaaaataa atatgtatcg aagtaaaaaa aaatgaccta tataggtcat ttaaattaaa
    34981 ataatgttta cagtccatgg attacttata catattttct catattcttt aaagcatttt
    35041 tttcaattct tgatacttgt gcttgagata taccgatttc atcagcaact tctatctgag
    35101 ttcttccttt gtaaaacctt aaatctaata ccaacttttc tctactattt aatttcttaa
    35161 tagcttcttt aagtgatatt tcttgcaacc aattttcatc agtatctttt ttatcttgaa
    35221 cctgatccat aacgaatatt gcatctccat tgtcttgata tactgggtca aacagagata
    35281 ttgggtcttg tatggcatca agtgccatta caactgattc tacttctaat tctaattcct
    35341 ttgctatttc tgatactgta ggttctttag aatttgttct aattaatctt tctctaactt
    35401 gtagtgcctt atatgctata tcttttaatg acctacttac tctaattggg ttattgtctc
    35461 ttagatacct tctaatttct cctataatca taggaacagc ataagttgaa aaccttacat
    35521 tttggcttaa atcaaagtta tctatcgctt ttataagacc aatacaacct atttgaaata
    35581 aatcgtctat attttctcct ctgttgttaa acttttttat tacactcaag actaatctta
    35641 aattccctct tacaaactgt tgtctggctt cttcatcacc attttttatt tgtaataaaa
    35701 gttccttcat ttgcttattt ttaagaactg gaagttctga tgtattaaca ccacatattt
    35761 caaccttatt aacttgcata tattttcagt cctctctcaa aagtattcat ctattgaaat
    35821 tatttacatt tccaattttt ttatactttt taagaagaat taatttagca ttatacaaat
    35881 tttttcattt ctttttgcaa ccttgagatt attttctttt caagtctaga tatgtaggac
    35941 tgtgatattc caagcattcc agcaacttct ttttgtgttt tttcaatacc tttatcaata
    36001 agaccaaatc ttaattccat aatttgcttt tctctgtcac ttaatctgtc aagtgccata
    36061 accaacaaat ctctatctat ttcttcttca attattttgt atatttcatc attttctgta
    36121 cccaatacat cagataataa aagttcgttt ccatctaaat ctatatttaa aggttcatca
    36181 aatgatactt ctgttttctt tttattattt tttcttaagt acattaatat ttcattttct
    36241 atacatctcg aagcataagt tgccaatttt atatttttat tcagtttaaa agtattaact
    36301 gcttttatca aacctatagt tcctattgaa atcaaatctt ctacatctat acctgtattt
    36361 tcaaattttc tcgatatgta gactactaat ctaagatttc tttctattaa aattgacttt
    36421 acactttcat ctgtttctag cttttgtaaa agctccattt cttcttctgg tttcaatgga
    36481 ggaggaagta tatttgcccc tcccatatag tatattccct ttggctttat tatttttaat
    36541 ttaataccta acatagtaat aaagcttatt attctttctt tcaatcgtaa cattccttgt
    36601 cccccttaaa ttttcaccta aaatccaggc aatatatttg gattcattat tgctccatat
    36661 tctctatcat taaaatttga aataccaagt attatatttc ctatcttttg ctcatctact
    36721 tctatatagt cagcttttaa gcctattatt atgcttgtct tattacttcc agcatgttta
    36781 taaggtatta ttctaactct acctgaagtt ttatcatcta aacttcctat aatttcttgt
    36841 gctttcttca tatctatatc ttcataatta atatttaata gtttttctgg aataaatcct
    36901 tctaacacac tagacttaac tattattaca tcactttgac ttattgggtc ttttaacaaa
    36961 ttaccactat ctactaaagc cttacagcaa aaactttttt ctagtaagtt tatatttata
    37021 gtctttgtaa gctccttaat gtacttaagc attttcaaat ctttataaat gtattttaat
    37081 aattcacaac tcacataagt acatgcaatt aagaaagata tttttaagtg acttattcct
    37141 gtaaaataaa ttataaaata agtgcttcca gaaataaaaa tgtttactag ataaaaaact
    37201 aacgctacat gaacataatc ttttttgctc ttacttctaa atgaaattaa agttattata
    37261 ctcatgatta ttattttaaa tggtacagta aatagtatat tcattgatgg atacaaataa
    37321 gcaacagaat aggcacctcc taaactagcc cccaataact tatttttttt aggattatat
    37381 cttttagtaa gaatagaagt acaacttata ataatataat ttattactag gttttctata
    37441 acatagtact caatatacac catgtatccc cccttaaaac ctttaaacat attataagat
    37501 agtatgtaca aaattttatg tcacttttga tggtcgaatc caaaacaaat tctatttaaa
    37561 aagaacaatg atatatgtct tatactttat gtcgtcaaaa gatatttttt taatgccaaa
    37621 caaatagact tttttgtaga atccaatata tctaggtaga agttattcgc tctacttttg
    37681 gtatatttac aaaaaaagac tacataattt aataatatat caagtaaatc ttttacttat
    37741 ataaaatcaa attatatagt ctgtaaattc aaatataaat tattgtgcta gtaatccatt
    37801 tgcatatttt gcagattcat ttagtgcttg ttctggagtt atgtctccag ctatcatcat
    37861 ttgaagttgt ttccataaat attcatatat ctctactcca tgaggtccaa ctgtcaatgg
    37921 tctatacata tgtttatctc ttgtcaccat ttcttcaaat cttgggtctc cttggtattt
    37981 ttcaccttta gcaactggag ctctaggtat ttctttgtgg aaagcttcca ttgattcttt
    38041 gcttagcata tactcaagaa gtttaaatcc aagttcttta tttttacatg ctgacattaa
    38101 tgttaaatca tctactgaag caaaacttcc aactgtctta tcttctaatg atgttacata
    38161 tccccagttt aaatccggga atgatttatc aaatgtactt gtagcagcag aggatagcat
    38221 tatagtaaat gcagcttttc ctggtccaaa tacactttca atcatttcat tactatcttt
    38281 tgataaagca tcttctggaa tatacttttt catatcattt ataaagtttg cagctttcaa
    38341 gccttctgca ttattaaatt taactgattt taaatcatca ttatatatat ctccaccagc
    38401 ttgccataaa tacggatacc agttccagtt taagcttcca aatactttag aaccccaacc
    38461 ttgtgcaaga ccccactggt cgatttttcc atctccatca gtatcttttg ttgctttttc
    38521 acagattctt ttaaaatcat cccatgtttt tggaggtttt tctcctaatt tttctagtat
    38581 atctttattg tagtacaata cgcctggatt agcagcttct ataggtaaac cataaatacc
    38641 acccatcatt tttgcatcat ctaagtatag ataattatct gaagttcctg atttttctaa
    38701 ataaggtgtt aaatcttcta ccgcacccat ttctataaat tgaggaaaca tctctgcata
    38761 catgtatcct atatctggac cttcacctgc acttattgct gttgcatatt tttctgcgta
    38821 gttatcccat ggtactatct gaaattcaat ttcacagtta ttttcttttt caaatttttc
    38881 aaatatcggc ttccatgcat ctgcatcatg gtctgttaat ggtgcagacc atacaactaa
    38941 tttttcttta ccctctttgc ctttagaatc ttcttttttt gaacatcctg caagaattga
    39001 tactgataga atccctacca taactaaaga aagaaccttt tttagtttaa tcatgcttaa
    39061 tcccctttca gactttaatt tgtctttttc ctcaaatgtt tacatttaat tcagatttaa
    39121 tattaacaaa taagattact cttgtctaat cataaaaaac tatactaact cctataacta
    39181 tatttttttt ctatacctat tagatttaat tcatactaaa aacttacttt ttaaatttta
    39241 tcaatattta aaaatttttt taagtctagc cacaaactaa ctatctaaat tgagcaaaat
    39301 aaaaagaagt ctattgactt ctttataagc ttacatatta tcttcttctt cttaggaatg
    39361 taggtatctc catgctctca tcatcatctt cttcaattat acttgccttt ttaggaggct
    39421 ctattttttc ctcagcaatt acttcttctt caatttcttt tacagcttgt tttactgttg
    39481 tatttaatga agaacgtatg cttgatttag gtttagtatc taaatctaag gcaccatttt
    39541 gtaatccttc aaatcctgtc gcgattactg taatcattat ttcatcacct aaatcttctt
    39601 ttatagaagc tccaaatata acatttgctt ctgggtcaca ggattccata actaaagttg
    39661 atgcctcatt aacttcaaat aatcctaagt taggaccacc tgtaacatta agaagtactc
    39721 ctttagctcc ttgtattgat gtttctagaa gtggagattg aatagcttgt cttgcagcat
    39781 caattgctct agtttcacca ctagcactac ctatacccat atgagcaagt cccttgtctt
    39841 tcattatagt agtaacatct gcaaagtcca agtttattaa cccttcaact gctataaggt
    39901 ctgaaattga ttgtatacct tgttttaaca catcatctgc aactgcaaaa gcatctaaca
    39961 ttgatgtatt tttttgtact atctgtaaaa gtctatcatt tggtatcgtt ataagagtat
    40021 ctacttttga tttaagttct gctattccac cttcagcgtt cttcattctt atcttacctt
    40081 caaatgcaaa aggtttggta actacaccta ctgtaagtat ccccatttct tttgccaagc
    40141 ctgcaaccac tggagcagct cctgtaccag taccaccgcc cattccggct gttacaaaga
    40201 ccatatcagc tccttgaagt aactttacta tttcatcttt actctcctca gcagctcttt
    40261 tccctacttc tggatttgct cctgctccaa gtcctctagt taatttttct cctatttgaa
    40321 ctttatattc agcttttgat gtatataaag cttgtttatc tgtatttact gatataaatt
    40381 caacgccttt tagttgagct tctaccattc tattgacagc attgtttcca ccgccaccta
    40441 cacctattac tttaatttgt gcacattctt ctaattctac gtcaaagttt agcatcataa
    40501 acccccttct ctcatgattc aaagttatcg tatgtattaa ttatatcatt ttcttctttt
    40561 attttgttaa cctttaagta acatattcca caaaaacgta aattttcctt tttaaatttc
    40621 ttacttatat tgtcaaatat tactctttaa gtataaaata atttacgtat atattaaatg
    40681 ctctttaatt tttacgtttt ttgttcataa tattactaat aatatatcgt ctaattatag
    40741 ataagttatt aaacaatctc ataccaaaaa ctaatacagc aacatagtaa agagaaactc
    40801 ctaacttttc tcctatataa gtcaataata tagccaatat agcattacct atgaaaccag
    40861 taataaaaat tacattatca tagttatctt caaaattgga ttttatcgct ccaaaaatag
    40921 aatccattat tgcaagaata gctactgaca tatatatgga ataatccata gaatatgtaa
    40981 atggaatata gtaacctact actacaccaa atgctaatcc tcctaaaacc cataacataa
    41041 atcttcacct ctttatttta ctttgaaaca caactacatt acaatccttt ttattaattt
    41101 tttttacttt ttctttattt ttttgtattt ttcgttttat tttgcaaata aattcacttt
    41161 atttccatta ttttcctgaa cttttatatt aattccatat atatccttaa gagatttagc
    41221 atatgattct ggagagttta tagctgcact caataaatct atatctccta tagcttttat
    41281 tataaatggt tgtccatatg tagtatcatt tactgtaata gtagctcctg aacattttat
    41341 cttacttgtt gctagtactc tttctccatt tatagaaatt gctcttgctc cagccttttt
    41401 taaatcattt aaaaccctca aaatatctat atcatgtata atcaaatcgt ttggattctg
    41461 tccgtctttt aactctctct cactatccct catagtaata gttatgcctg gccctgtaac
    41521 agttgaataa ccacttaatt ctttaacttc ttcaagctct ttttgcataa gtgtttggat
    41581 agattcattt ccattctttt ttgcttcttt atattcattc aaagtttttt tgttcttttt
    41641 aagagtttct tttaagtttt ttatttcttt ttttgtattt tctacctcac tttcaatact
    41701 ttcagtttga cctaatgtta tgtatactct atttgggtct agtgatttta tataagttga
    41761 tatgaaaacg cctaatatga atgctcctaa tataactatt ttctttttca tactattatt
    41821 tcccctctgc tttgtttata tcactatgac catttatttc tatattgtct tctttggtca
    41881 cttttacttt ggcattataa tatgtttcta tttcccagac aataccatac tttatattaa
    41941 gtgccgaagc caatgtatca gaatcaccaa ttgcttttat tataattggt tcttttatga
    42001 cagtgtcatt catataaagc ttgtcttctt ttaaatacat atatgtatta gaaactattc
    42061 tctggtcgtt tatagatatg gcacttgctt gtgctgaatt taatttattt atcattgata
    42121 ataataaatc ataattatat agtatactat catttttatc agagtttcct aagtcttttg
    42181 tagaatttat ctcaattttt atgcctgttc cttcaacatc tgtatatcca gctaatgttt
    42241 catatttttc tatttctgac ttaagtatgt cttgttctcc ttcattgttt ttgcctctat
    42301 aaatctctat atctttcttc acactattaa cttctgattg tagattctct ttttcttttt
    42361 ttaaagattt aagttcttct gtaagttgct ctcctctttt aaaagttgtc atccctctat
    42421 tttctatatt aataatttta agttgtaaac taacaagaac acccaataca atacttccta
    42481 tgattatact tttatttata aatctttttt tcaatatatc acttccttac aattgtctat
    42541 ccttctggac tatacactgc caactttcca tagttaagat ttatagtccc tccattagta
    42601 tttttatttt gcaggtcaat cagaatttta cttaccctag atatattata atctaagtta
    42661 tcatcattag aaagtaagat ttttatatta cttcttgtaa gcatttctat attgctttct
    42721 ttttttaagt ttacataatt tatttttcta taaattcctt cttcttttaa ataatttaaa
    42781 gttttaaata cattctcctt agttttataa tttttaaatt ttatagattt attatcatca
    42841 atgctataat ctacatctac tatcaagtct tttttacttt cattagaacc tcttagttct
    42901 tccaataaat ttcctttttt atctatataa caataattat cttcatcttt taatactgca
    42961 aatatttctt tttcttttaa acttataatt atcttattgg gaagttttct ttttatttcc
    43021 acattttcta tatatggatt ttttataagt ttatttttca tatctttaaa attgtatgca
    43081 aaaatatttt catttagatt tacatttagt tctttcatta tatttgattt ggtcaccctc
    43141 ttatttccaa ttacatctat tttctttaca tcaaataaat cactttttac aattatacat
    43201 atacaaaaag ataacataag tataaaaact aaaactatca tgacattatt cgtatttaac
    43261 tttcttcttt ttttcaaata taatcaaccc ctttggttaa taaatacacc tttagagctt
    43321 gtttttccta caaaaaaatt ataatattta aagtcaaatt tttgcatttt attacataac
    43381 atccaaataa ggtattaaat tttataaata aatcaatatt tcatcaaaat aaacatagca
    43441 tactacatac tatttatata tttaaatctg tatacataca aataaacccc taatttataa
    43501 taatttagaa aatctaatat attataaatt aggggtaaat atttacttat cttttcttta
    43561 ttcctattac cttagcttga ccttctatac ttggagtcgt ttcttttttt atttctttta
    43621 cttccttaat aactttttct ttttttgttt ttttagaagt tgacttttgt gttgaattgt
    43681 atactttcat tatctcatca tatataaggt ctatggcttc aggcttacct atagttttac
    43741 ttgcatttgc catatcaacc aaaagttctc tatctcctaa aagtttaaat actgctgtat
    43801 ttaggctctc tggagttaga tttttttcta aaatagcaat tcctgcccct tgtttttcta
    43861 tactcttggc attatactct tgatgatttt cagcagtata agctttaggt attattatag
    43921 atggctttcc aagagccgtt atctcagcta atgaaattgc tcctgcgcta cctataacca
    43981 aatcacttgc tgcaagtgca tttgccatat cttctaagta aggcacaact ttttggtatg
    44041 gtttaagatt tatatcgcta atacttccca taaattcatc ataatagctt ttgcctgtag
    44101 caaatataaa agctatatct tcatttacca tattctttat tacaagtctc attgcatcat
    44161 ttatttttct tgaacctcca ctaccaccat agcaaagtac cattcttttt tcgtcactta
    44221 ttgatagatt ctttcttgca atattttttc ttgataataa aatttctttt ctaactggat
    44281 ttcctgtaaa aactaattta tcttctgctg cctctggaaa tcttttatgc gaatcttcaa
    44341 aacttgtaag tacctttgta actgttttag ataaaatctt attagttaca ccaggaaaag
    44401 aattttgctc atgtattatg gctggtattt tccccataga tgcattaaat aaaacaggtc
    44461 cactaacata tccaccagtt cctataacta tatctggttt aaatttctta acaatctttc
    44521 ttgattgctc caaaccttta aaaagcttaa aaactctttt tacattatcg aaatctattt
    44581 ttcgcttaaa gccttgaact gttacagtct ttaattcaaa tccatactta ggaactattt
    44641 ctgactctat tcccttttcc gtcccaacaa aaattatctc agcgtctgga tgctcatctc
    44701 ttattttgtt tgcaatagct atagctggat acacgtgccc tccagttcca ccgcctgata
    44761 ataaaacttt catcaaatca tcatctcctg ttaattaatt ttgacatgct ttgagatgtt
    44821 taacactatt cctacagctc ccataaagat ggtgagtgaa gttcctccat aacttataaa
    44881 tggtagtgct acacctgtag ctggcattga tgatgtcgca actgctatat ttaaagctgc
    44941 ttgtattcca atttgtgcac ctatacctat aacaaccata caagcaaata cattagaagt
    45001 cttcaaagct attcttacac atctgtagac taaaactaca aatagcataa taactattat
    45061 acaaccaatc aatcctaact cttctcctat tatagcaaat ataaagtcat tttgtggctc
    45121 tggtatataa aaatactttt gtttactctt tcctaagcct agaccaaaca atccacctga
    45181 acctagtgca tatagacctt gtattacctg atacccctta ccaagagggt cttgaaaagg
    45241 gtctaaaaat gatgtaacac gactaagtct atagggttca gcaattacta atgcagcaaa
    45301 taaagcagcc ccactcccta tcatagcaaa tacaattttc atatccattc cagcaacaaa
    45361 tatcattaca aaagtaacta gaattacagt acctgctgtt gacaaatttg gctgaagtat
    45421 tatcaacgca aaaaatatcc ctggaactac gagaagtggt acaacacctt ttgtcaaaga
    45481 ttttatttta tcataatttt tttcaattaa ttttgcagtt aatattattg tagcaaactt
    45541 tgcgatttct gcaggttgaa atgttaaagc tcctattccc aaccatcttt ttgctccgtt
    45601 tgcttctatc cctaaagggg tcaaaactaa caataataat actactgcta tagctccaat
    45661 tgctgtagca tttttcttcc aaaaactata atctattctt gatgtaataa tcataactat
    45721 aaatccaagt acagcatata ttacattctt ttttagaaaa tagtacgcat cattgtgttt
    45781 aaatgaagat tgtataaaac ttgcactaaa caccataact attcctacaa atactaaaag
    45841 catagtagtg taaaacacta ctccatcaaa ttcagtcttc atccttatgt caatttgttt
    45901 tttcaaattt tctttaggca tccaactaat ctacctccat tcttccattt aagtaagttt
    45961 agaggtaaga gattatttta aattgtttac attatctttg aagtcttttc ctcttacttc
    46021 aaaactttca tacatatccc aacttgcaca agctggtgaa agaagcacta tatctccact
    46081 ttttgaaatt tcataagaag tcttaactgc ttcttccata tcttttacta tatgtatgtc
    46141 attaaatcct ttatttttag cacaattttc tatatttgat gcagtttctc ctaataagac
    46201 caatgattta acatatgact ttgcagtttc aagaagttca tcaaaattac ttcccttatc
    46261 catcccccct gctataagta ttataggtct atcataagac tgtatagctt ttatagtgga
    46321 atctggatta gttccctttg aatcatttac atatattaca ttgtctaaat ttcttacaaa
    46381 ctcttgtctg tgttccactc ctttaaatgt cataagtaca tcctttataa cttctaaatc
    46441 aattttgcag acatatgcta ttgctatagc tgccatacaa ttttctaagt tatgacctcc
    46501 aggtaaactt acatcatctt tatttagaaa tttgatttta tcatctatat ctattattat
    46561 gtcattattt tctaaatata ctcctccatt tactttttta gttcttgaaa agtaaattac
    46621 tttggcattg catttatcag ctaaagattt tactatctca tcatcatagt ttaatacaca
    46681 gaaatcctca acagtttggt tcataaatat atttgccttt gcttctatgt atttttccat
    46741 agtatggtgt ctatttaaat ggtcctctgt aatatttaat attgcgctta ctttaggtct
    46801 aaattcatct atactctcaa gctgaaaact gcttagttca gttactaaca cagactcttc
    46861 acttgaagtt tctatagtat ctattacagg atttcctata ttaccaacta catatgtatc
    46921 tcgttttgct cttgaaaaaa tttctcctac caaactagtt gtagttgtct ttccatttgt
    46981 acctgtaatc cctataaaaa ttggattatt cgatagttta aaagctaatt ctacctcacc
    47041 aattatatac ttgcctgaat tttttaattt caatatgaat ggtaggtcta gtggtacacc
    47101 tggagacact acaaccatat ctatatcatc tacatcttct gggtgatgtc ctaatatgta
    47161 ttttatgtca tttatagatt tcaattcatc aagtatattt ctcaatttat tttcatcttt
    47221 tatatcattt acgattacac ttgcacccaa tttatctaaa tgtttaattg tagatatacc
    47281 agtttttgca agtcctacta ataaaacttt ttttcctttt aagtccattt ttcattcccc
    47341 ctagccctaa aatactgcta ttatacttat ccaagctaaa acaactgtta taatccaaaa
    47401 aataaataca actcttgttt ctggccaacc acactgttca aagtggtggt gtattggagc
    47461 catcttaaag aatctctttc ttgttgcctt aaaatatcca acttgaatca aaactgatag
    47521 agcctccgca aaataaattc ctccaattat aggtattata agcactgagt tagttagaac
    47581 tgaaaatgct acaactgcac ctcctaatgc cattgaacct gtgtcgccca taaacactct
    47641 agccggatat gaattaaatc ctaagaaacc taaacatgct ccaacagttg ctgctgctaa
    47701 aactgcgact tctgtatttc cagcaataga acttgcaaat agcataaaga atacagaaac
    47761 tattaatgtt actcctgatg ctaatccatc taatccatca gtcaagttta cagcatttac
    47821 tattgctacg attataaaca tcattattgg tatatataat attccaacat ttatcacaaa
    47881 atctgtaaat ggtatcataa gttgtgaagc acttgatgat gatgtatact gataaaaagc
    47941 aacataaaaa gataatgcaa cttgaaggat tattttttga tatgctttta gtccaagtga
    48001 tctttttagc tttattttta taaaatcatc taaaaagcca ataaaaccaa aacctgcaat
    48061 acatataaga cctactgcca tatcatgact aacttttact cttgtaagtc cagttattag
    48121 aattgcaaca atcattataa ttccacccat agtaggtgtt ccgtttttag ctagatgtgt
    48181 ttggggtcca tcatctctaa ctgtctgacc aaatttaaat tttctaagca ttggtataaa
    48241 tattggtcct attataatta ctattaaaaa cgcaatcaat gcggtgtacg taagctctgt
    48301 tattcctaac atcataaaac tcctctccct tgtcaattaa ctcattagtt taagcttatt
    48361 tatttagata ttcgactatt ttttctaatc tcatgcctct tgagcctttt actaaaatag
    48421 tgtctcctgt ttttactaat tcatttaact tgttaaacac atcttctcta ttctcaaagt
    48481 gatatatatt ggctgaattg aatcctaatt gttttgcttc ttctccaata aacactgaat
    48541 tttcacctat agttattata atatcagtat tattcataga tgattttcca actaatctat
    48601 gaccatactc tgaaatttca cccatttcta gtatatctcc aagtatcgct acccttctac
    48661 ctttatatct tccaagtatc tttaaagcag catccataga atctggacta gcattatatg
    48721 aatcattaat tattgttaat ttttcatttt ttattatgtc taatctcatt tttgtccctt
    48781 taaaattttt taaacctttt tttatataat ctaaagaaat atttagacac aaaccaacta
    48841 atatagcaga cattgcatta tatatattat gttctcctat tgttggtata aatatttcct
    48901 cttttttccc atttattaca catataaatg ttaaactatc ctcttccata gtataacttt
    48961 cacaataaac atcattgttt ttattaaagc caaatgtttt taacttatat acatgttctt
    49021 tttcttttaa tgtagataaa aacttatcat ctccatttac aattaaagta tttgtttcat
    49081 caaagtttga agtaatctcc atctttgctt tcaaaatacc ctcttgtgaa cctagttttt
    49141 ctacatgtga taatcctata ttcgatatga ctgcaatttt aggatttact atatccacta
    49201 aatattttat ttcattgaat ccagacatac ccatctctat tacagcacac tcatgttctt
    49261 tatttagatt aaataaagtc aatggaactc caaaatgatt atttaagttt ttttcatttt
    49321 ttagtatatt taactttgca gatatggcag agtaaatcat atctctagta gtagtttttc
    49381 ccacactacc tgtaacacct ataaatggaa tatcaaattt ttctttatag tattttgaaa
    49441 tatctcctag agccaaagat gtatctttta cctctattaa atttatatcc gaactttcta
    49501 attttattcc attactttca ttttttataa aagttttaca tccactatca tatgcagact
    49561 tcataaatgt atgcccatct aaattttctc caactatggc tacaaatgca ttttgggcat
    49621 ttgcctccct gctatctata actatatcac ttacacagtc attataatct ccatatatta
    49681 acttcccatt agttgcaagt actaactctt ttattgttaa gcactccatt attaaactcc
    49741 tcctttaaaa ccttagctat attctcttag caacaaaagg caatgtatac cgttatatat
    49801 acattgccta cgataactct taactttata attatatact atatttctgt ttttttgaag
    49861 atgtttatgg gtatatgtta attatctgtt actttttagt tttcaaaata tagggttata
    49921 cttgagtctt cattaacttt tactccaggt tttgggaata tatcctttac ctttgtatct
    49981 tctggaagtt ctatatctgc atctaagtct ggttttaact tcgcatcctc caatgccttt
    50041 acagcatctc ctatttttag atttcttaca tctggcactt taacttgctt cttttcatac
    50101 tcagcttttt cttcttcttt atatactggt ttaactccca aatattttaa agagtcattc
    50161 attatttctt tcactattgg tcctgctgta gtactaccaa atgcacttac tcctgttggt
    50221 tcgtcaacaa tagcaagaac tactatttgc gggtcatcac aaggtgctat tccaacaaat
    50281 gaacatatat attttcctgg agcatactta ccatctataa ctttttgagc tgtacctgtt
    50341 ttaccaccaa gtctataacc tggtatatat gctatctttc ctccaccttc agttacaact
    50401 gattctgcaa tttctaacat ttttttagat gtttctttag atataacact tcttactttt
    50461 tttggtttta ctgtttcagt tatatttcct ttattgtcag tataagattt taccactctt
    50521 ggttgcatta aatctccacc attagctatt gatgatatag ctgttataag ttgtattgga
    50581 gttactgata tagattgacc aaatgatatt gtagccaatt caactggtcc tacatttttt
    50641 tcgttataca gtattccctt agcttctcct ggtaaatcta tacctgtctt atccataaga
    50701 ccaaatgatt ctatataatc atacattttt ccaacaccta atctgcttcc caactcaaca
    50761 aatactgggt tgcaagagtt ttgtactgct tgtttaaatt cttgtgttcc atgaggtctg
    50821 taatgtctcc aacatttaat ctttcttcct ccaacagtta cactacctgt acatgtgaat
    50881 ttttctccat ctttaattac tccttcttca agagcactgg aagatgtaat aagcttaaat
    50941 gtagaacctg gttcatatgt atcacttact gctggatttc tccacatttg ataatagcct
    51001 tttattttat ctttatcatt atatttttca agttcttctt gataatatgg atatattggc
    51061 gttcttgagt cattagggtc ataatctggt tttgatgcta aagcaagtat atcacctgtt
    51121 ttagggttca tagctattgc agtaaccttt tttgcattat ttaactcata agctttctgt
    51181 actgcttttt cagtatagtg ttgaattact tcatctatag acaacacaag accattacct
    51241 tgtacaggct cataatattt ttccattcct tgtggtattt ctcttcctga agcatcagta
    51301 cttactataa gttttccagg ctttcctttt aactttttat catattgcat ttctacacca
    51361 gatatacctg ttgcatctga agaagtatgt cctaacacat atggtgcaaa attcccatat
    51421 gggtaatatc tttgattatc ttctgccacc catattccac ttaatttagc atctcttatt
    51481 tgacttgcct tatcatcatc tatccatctt tttactttta caagagccat attttttttg
    51541 cttattaaag cgtaaatatc tttataatct tcatccaaaa tctcagctac cttttcggct
    51601 gcttcttttt tatcttctac ttccacaggt ttacaccaaa cagtatactt agttacactt
    51661 actgctaact ctttcatatt tctatcatat atagttcctc ttttgggttc tattggtata
    51721 tctcttgttt gttgttctag tgcttttgta ctcaaccaat ttcccttcat aagttgtaga
    51781 tacccagtcc taataacaag gcaaaaaaac aatgcacatg ctagaataag aacgagtacc
    51841 agccttttct tacttatcct ctttactttt ctcaaatcta ttccccctag ttatccacat
    51901 ctatatactt tatttgtcca tcttttggat agtccatatt gagcaattcc ttagccttta
    51961 gctcaatttc ttttattgat gttttttcag tttcttttgc ctttagttcc tctaatacta
    52021 tctctttttt tcttaaatct ttttgtaaat aatagatatc gtacttcatt tccgagattt
    52081 ttgaataacc acatagattc aatattatta ctgaaaaagt tgcaatcagt aaaatgcatt
    52141 tagctcctat ttttttctta tttctctttt tataattatt ctttttttta tttttatatt
    52201 catttagatt atgtatttta taattttttt tcaaattctc accccgatag tatatagttt
    52261 aaattttcct ctatactata tttgttatta atcatatttc ttcctctaaa atttcatcgc
    52321 taaattaata cactattaca caatctaatt gtattttttt ctatacacaa caaaaaccta
    52381 taaattcact tatactttta tatgaatcta taggttagat attaatttct atttattttt
    52441 atcacttcta gtatttttag ataatttctt ccataaatat aatatgtaac taactatcta
    52501 ctctctgatt cctaagttct ccattatatt acttaatacc atctatatct atatttttat
    52561 atctaaattt tcattatata tctcaataac aaagaacatt tcttatagtg ttaattgttt
    52621 tttaattgct ttaccagtgc aacaaaatat ataatacttt ttaattaatt ataataatct
    52681 tattttatat ataagattat tctttagcct tataactact tatatttttt ctgctactct
    52741 tagcttagca cttcttgaac gtggatttac ttctatttct tcctcactag gtaatatagg
    52801 ttttctagtt attattttca cctcagattc tttatcacat tggcatatag gtaaatgttg
    52861 tggacatata caatctgatg ctaaatgctt aaatgcattt ttcactattc tatcttctaa
    52921 tgaatggaat gttattatac atattcttcc accttcattc attatagaag aagcatcatt
    52981 tatcatcttt gtaattactc caagttcatt atttacttct attcgtattg cctgaaaagt
    53041 tcttttagct gggtgaggtc catctattct agctttctta gggatagctt ttttaattac
    53101 atctactaat tctcctgtag tttctattgg tttgtttgct ctttcttcaa ctataaattt
    53161 agctatacgc ttagcccagt tatcttctcc ataatctttt attatcttag ttaattcatc
    53221 ttctgtataa gtatttacaa catcatatgc agaaaactca cacctaacat ccattctcat
    53281 atcaagtggt gcatcttgca tataagaaaa tcctctatca gcttcatcaa gttggtgaga
    53341 tgaaactcct aaatcagcta atacaccatc aattttgtaa actcctattt tttctaattc
    53401 ctcttttata ttttcaaaat tgctgtgaac aaacttcact ctactttcat attcactcaa
    53461 tctctctttt gctgtgctta tagcattttt atcttggtca aaccctataa ataatccctt
    53521 atctgacagt ttttttacta tttctttaga atgtcctgct cctcccatag tacagtcaac
    53581 atacacgcca tctggcttta tatttaaatt ctctatacac tcatttaaaa gaactgatac
    53641 atgatgaaat tccatagtta cctcccttaa attcactttt taaactattc ttcactaata
    53701 ttatttttat ttttctttga taaataaaca tgtgcaatta tgccaccaat aactccaatt
    53761 agacttataa cttgtgccat tctaagtggt cctaacatta aactatctgt tcttaatccc
    53821 tctataaaaa atcttcctat tgaatataaa gttatataag taactataac ttgaccttca
    53881 tattttttat tttttctaaa tagtaataaa actataaata ttccaaaatc ccatatagac
    53941 tcatataaaa aagttggatg tacctttact ccatcaacca ttattcccca aggtaaattg
    54001 gtagcacctc catgtgcttc tccattaata aaatttcccc atcttccaat agcttgtgct
    54061 aaaggcattc caagtataac tgtatcagcc atttttaaga agttaatatt tttaatctta
    54121 gtgtatatat aaccagctaa tattccacca attaaccctc catgtatagc aagtccacca
    54181 cctctaaaat taaaaatttg agacatattt tgagcatagt aactccaatt aaatacaaca
    54241 taatagattc ttgcacagat tagtccaact ggaattgcta ttatagctat atttaataca
    54301 tcatcttctt taattcccac tctttttgct tcttttattg ctattaaagt tcctaaaatc
    54361 attccacatg ccataagtat tccataccac atgatgtcta tgccaaacag tgtaaatgct
    54421 actctatcca taacgtcacc tctttgtatt aattgaaaat atttccaaag caatatgcta
    54481 taattacaat taattgtaat tatactaaat tatgataaca cattaatgtt aattctacaa
    54541 aaaatattaa aatttattct acaactccct acactatatt atatctaatt actataaaat
    54601 tttttaaact gaatctctca tgactaaagt tacaagtgta catagatatt ttttaatcaa
    54661 aaagattgat gcatatatac atcaacctct tctaattctt atctatagct cttaaatttt
    54721 tacctcaatt tatataaata tattttataa atttgtttta ccaaaataaa catttaaaaa
    54781 cataaactaa tacttaatta gttattctta ttatgattaa gtttctattt aggctctaca
    54841 atagaaataa cacaatactc ttctttaaaa tgctctttta atctttcttc aacttcctca
    54901 aaagtaatat ctttaataac atctaaatac tccaatagat ttatatcctt aaaaacataa
    54961 gatataaaac tattacctat aaagtttata gaatcaaagc acttaataaa tgaccctatt
    55021 tttttctttt tagttctctc aaactcttct tttgataatc cttctttttt tgatttttct
    55081 atataatcaa gaattatttc ttttactttt ttaggctctt tagaatctcc agctattatg
    55141 ctaaaagcat aatccacttg agacgaaaat ccagctccaa aattttcatt tattaaacct
    55201 tgcatataca aatcttcata aagcttactt ccttttttaa ataacatccc tacaagtata
    55261 tcagttacaa tctctttacg taaaagttct ttccctttta aaccaacatt actatcttta
    55321 aaacctatgt tgaacatagg catagatata gggaattttt ctataacctc tttttctttt
    55381 acaccttctg gttcttctgg ataaaatctt tctatactct tagagagttt atctactttg
    55441 taattgtttg actttttagt tacatctata actttttcta catctaagtc accaacaaca
    55501 aataaagcca tatttcctgg attatagaaa gtattataac atttatatag ctcttcctta
    55561 gttatcttat atatactatc aacagtacct gctatatcaa ttctagcagg ataatttaca
    55621 tacattgcct tcaagcaatt aaagtataca ttccaatcag ggtcatcatt gtacattttt
    55681 atctcttgtg ctattatacc tttttccttt tcaacatttt catctgtaaa ataaggtgtt
    55741 tgaacatagt caattagatg ttctaaactc tcataaaaat tttcagtagc agaaaataag
    55801 taggctgtca ttgtaaaatt agtaaatgca tttgcattta ctcctaattt tgaaaattta
    55861 tcaaatgcat ctcctccatc aggttgctca aacatcttat gctctagaaa atgtgcaata
    55921 ccttcattca ctctaatttt cttatcttct ccaattggta caaattctaa gtcatttgaa
    55981 ccataattag tagctaaaat agcatacttt ttcataaaac cccttttagg cataaaatat
    56041 acatctaatc cattttgcaa tttctcataa taaacttctt ctttcaatat atcattaact
    56101 attttttcca tagacatctc ctccattaat ttctcaagaa gtatacagta tcaagctcta
    56161 tattttttat agcttcaact atatcttttt ttgtaacctt ttctatacta gatattatat
    56221 cttgtacttc agaatttgtc tttgccatag attgagagaa aacaaaatca gacataccac
    56281 ctatattatc agttatagat ttcatagaat taactaaagc aagtttactg ttttctaatt
    56341 cttcatcaga tatatcacct gcttttacac tttctacttg tttttttatc aattctacag
    56401 ctttatcata atctttagtt tctataccag atgatataaa catgatactt ttatacttct
    56461 ctattgaaga gaatatatag taacataaac tttctttttc tcttacatta acaaataatt
    56521 tagagtgtgg accaccacct aagacattgc tcccaactac taaagcataa tatttatcta
    56581 tgtctgcata atccacattt gctctataac ccataactaa cttaccttga gttatttcca
    56641 tttgttcatc tataactttt acctcatcca cattttttat aaaatctgct cttggtatat
    56701 ttataatttc ttctctttca aattttagat ttttacttat tatatctaca actttatctt
    56761 catcaaaatt accttctaca actatatcta taggtgatgt tttaagtatg tttttataat
    56821 gttcatataa ctctcttgaa gttatactat ctatttcatc ttcataacca aattcactta
    56881 cactatatct ctctccttta cacatagcct caatacattt atcttgcgca tattcctttt
    56941 tatcatttat tattgattgt atcttttctc ttaaattctc tttttcaata tttaaatatt
    57001 cttctttaaa cccaccatct acaacaagcg tattatttat tacttcatta aaaaattcta
    57061 ctacttcttc aaatatactc tcatctaaat acttttcact tatgttaatt actttaaaac
    57121 tcaatacttg acgttctcca cgttttacag catcagctcc catagatgaa ccgtataaat
    57181 catctaattt attggatatt gctctagcac taggatattt agagcttcca cttgctatta
    57241 ttgatggtat tagagcattt tttgtagttt ctttttcatc caatagtctc tgaacatata
    57301 aacttataag attcgattta aacttttctg tttttatcaa agtaagatta atattattac
    57361 ctaaatttat tattttttta gtattaacca tatgtacctc ctatttttat ttaaacatca
    57421 attttaaaat tgaaatttat ttatttttta attacatata ctcacatata aaaaccttct
    57481 atttaattat atccttttta ttattttcta aaagcaatat ttttatttaa attaaataca
    57541 aatattattt aaatcaatat gctttaaagt ctagtttaca agcttgatat atatgatgta
    57601 taatcaatat gtatgtctat aattaaaaca attttgcaat cctatagatt gattgtttaa
    57661 agttatataa agaatataaa aaagaataag agagaggacg attaatatga aattaggtat
    57721 agttggttta ccaaatgtag gtaaaagcac actatttaac gcaataactc aagcaggtgc
    57781 agaatctgca aattaccctt tttgtacaat agacccaaat gtgggagttg tatctgttcc
    57841 agatgaaaga ttaaacaaac tacaagaatt atataattct gaaaaaatag ttcctactgc
    57901 tatagaattt tgtgatatag caggtttagt tagaggagct tctaaaggag aaggtttagg
    57961 aaataaattc ttatcacata taagagaagt tgatgcaata gttcatgttg ttagatgttt
    58021 tgaggatgaa aatgttgtac atgtagatgg ttctgtagac ccacttcgtg atatagaaac
    58081 tataaactta gaattaattt tctcagatat agagattctt gaaagaagaa ttaataaaac
    58141 tcaaaaagct gctaaggctg ataaaacttt aggttctgaa cttgatttat taaaatcaat
    58201 aatgtctact ttagaagaaa gtaagtgtgt aagaactatg gaatttacag aagatgaaca
    58261 aacattcgta aattcattgg atttacttac atctaagcct gtaatatatg cttcaaatgt
    58321 atcagaagat gatttagctg ataatggaga aaataataaa tatgttcaac aagttaaagc
    58381 atttgcagaa acagaagatg ccgaagttgt tgtagtatgt gcacaaatag aagcagaaat
    58441 ttctgaactt gattctgctg aagaaaagaa agagttttta gaaacattag gtcttgaaca
    58501 atcagggctt gataagctta taaaatcttc ttatgcttta cttggtttaa tttcattctt
    58561 aactgctggt ccaaaagaag ttagagcatg gactataaaa gttggaagta aagctcctca
    58621 ggcaggagga aaaatacatt ctgatataga aagaggattt atcagagcag aaacaatagc
    58681 ctttaatgat ttggttgagc atggtactat ggctgctgct aaagaaaaag ggttggttaa
    58741 attagaaggt aaagaataca tagttaaaga tggagatgta atattattta gatttaatgt
    58801 ttaaaatgat taatcgtata cactttgact attatatata ataactaaaa aactaagatt
    58861 ataat
//
LOCUS       DAMJVG010000015        56929 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.015, whole genome shotgun sequence.
ACCESSION   DAMJVG010000015 DAMJVG010000000
VERSION     DAMJVG010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 56929)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56929)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56929
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.015"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            68..141
                     /locus_tag="PC512_001065"
     tRNA            68..141
                     /locus_tag="PC512_001065"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:100..102,aa:Gly,seq:tcc)
     gene            150..266
                     /gene="rrf"
                     /locus_tag="PC512_001066"
     rRNA            150..266
                     /gene="rrf"
                     /locus_tag="PC512_001066"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            540..2558
                     /locus_tag="PC512_001067"
     CDS             540..2558
                     /locus_tag="PC512_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF2440834.1"
                     /translation="MRRNTKLLTTGILSMAIVAPTMAFATESNAMENNADLNINLEKK
                     SIVLGSTSKVSVKFKEKPDADSITLKYKCYDMPLDTTLNYNQSTESYEGTINYNKDPE
                     YLNVWELQGITINSKNNPKTLNKQELEKMGLNLKDYNVTQECIIEDITSRKDVNKYLR
                     KTSAPITELTGSDRYETAVKISKEGWKNGSDKVVIINGDVSIDGIISTPLATTYNAPI
                     LLVEKNNVPNSVKSELKRLNPRDVIIIGDENAISKTTANQIKSTVNASQTRLKGSNRY
                     ETSLLIAKEIDKNHDVEKVYITNANGGEVDALTIAAKAGQDKQPIILTDKNSITDNTY
                     KWLKSEDLQNAYFIGGPQMISTNVINKVNDITKDNVTNNRVYGADRHETNANVIKKFY
                     TDDELEAVLVAKSDVLVDALAAGPLAANLKSPILITPKTYVSAYHKENLEAKSANKVY
                     KIGGGLTSKVMNSIASSLSKHNTTPTEPGNSGGKTVMIDPGHGGSDTGTTGKPLGGIK
                     EKDYTLNTSLATTEYLRSKGFNVIMTRDTDKTLSLGNRTALSNSLRPDLFTSIHYNAS
                     DTTGNGVEVFYKLKDKDGGTTKTVATNILNRILEKFNLKNRGAKTRTLSTDPTKDYLY
                     VLRNNDMPAVLVECAFLDNEKDMSLLNTSNKVKEMGTQIGKGIEDSLK"
     gene            3066..5078
                     /locus_tag="PC512_001068"
     CDS             3066..5078
                     /locus_tag="PC512_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF2440835.1"
                     /translation="MRRNTKLLTTGILSMAIVAPTMAFATESNAMENNADLNINLEKK
                     SIVLGSKSKVSVKFKEKPDADSITLKYKCYDMPLDTTLNYNQSTGAYEGTINYNQDPE
                     YLNVWELQGITINSKNNPKTLNRQDLEKLGLNLKDYNVTQECIIEDITSRKDVNKYLR
                     KTSSPITELTGSDRYETAVKISKEGWKNGSDKVVIINGDVSIDGIISTPLATTYNAPI
                     LLVEKNNVPNSVKSELKRLNPKDIIIIGDENAISKTTANQIKSTVNASQTRLNGSNRY
                     ETSLLIAKEIDKNHDVEKIYITNANGGEVDALTIAAKAGQDKQPIILTDKDSITDNTY
                     KWLKSEDLQNAYFIGGPQMISTNVINKVNGITKDSVTNNRVYGADRHETNANVIKKFY
                     TDDELEAVLVAKSDVLVDALAAGPLAANLKSPILITPKTYVSAYHKDNLEAKSANKVY
                     KIGGGLTSKVMSSIASSLSKHNTTPTEPGNSGGKTVMIDPGHGGSAPGNSSGGMIEKD
                     YNLNTSLATTEYLRSKGFNVIMTRDTDKTLSLGNRTALSNSLKPDLFTSIHYNGSTNK
                     QGHGVEVFYKLKDKNGGTTKTVATNILNRILEKFKLTNRGIKTRVLPSDSTKDYLYVL
                     RSNDMPAVLVECAFLDNENDMSLINSSAKVKEMGTQIGKGIEDSLK"
     gene            5320..7233
                     /locus_tag="PC512_001069"
     CDS             5320..7233
                     /locus_tag="PC512_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440836.1"
                     /translation="MEYLFEKSSLKEYGNEALDKYRELLDKTGNNSRCILLLVPNNNT
                     KIRYERALRLNYSEELKVTTYISFVKKELVKYWPLIIEKCDGISTKVVSPTFISNSLS
                     EYLIVQKVKEKRIQEGYFEDITGTNKSIANSIMTNINKSAFNLIDFDFIGEKIYSSKK
                     NKDSIYRFSYTQMDEIISYYINSLLSNSILDNALSIYLYNQYLLNDDFYLKNLFTEVR
                     YIIVDSLESSSNAEVDFITEALDNTLQSYIYFDYSRDYSVFNNVDIDYINEKIISKIK
                     PKEENIKKKEIRIEDLYLLPANIELNQSSQLYNEMLDLISEKVISLIEEDVSPRDIAI
                     ISPINNSILEHQIRDSLIEKNIDVFSTKKDKKAVDYPYGNALVVATCIFYGYLDFIKD
                     DEYLSFLETLLEINRIKAFKIFNETRHLSIDNIDEHSQYRDILQYIEEKKKSDIKIHE
                     FLTQFYIDKMLNLKEGKKNVGLCKKIIAESESFSESLSLLGMKKEKIFVEALKSTIND
                     YYSVVDIEELKSKDKIVITTPYSYISSNIDRSIQIWVDIGSNAWNMKIEKDISNLIVL
                     RKSFEEKKIYTNEMEEYYKKYYLYNTVYNLLLNAKKIYAFKSEYAINGYIQESILYSI
                     LLKISHKGDKNYD"
     gene            7226..9445
                     /locus_tag="PC512_001070"
     CDS             7226..9445
                     /locus_tag="PC512_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HDF2440837.1"
                     /translation="MININYREDQIPIINYDNGTMAVPAVPGAGKTFIITNLVAKLLL
                     EQKHKSGKILILTYMNSAVNNFKGRIRKILEENKIDDTNSYEVMTIHSLAVKIIKEKP
                     EVVMLSEDFNIADDLQKSIILNECISRFRFEGGERAFRWFLKEQKDERWKEITLEAWE
                     RGFFEFAGNAISELKYKGISPDKLEEILSRGHKGMLKIILPIYKLYDRKLKQNGLLDY
                     DDILILAEKTLSLDEGLRKKFQTRYKYIFEDECQDSNEIQGNIIKIISSENKNLVRVG
                     DINQSITGTFSSSDPKFFKEFINSADFCYRMDMSNRSSKDILDLANTLVKYVTKEFRQ
                     EECRHALEDMQIKTVPNGMGYKENPNPEHYNINVKWYESWKIEIEQTARYVKGIKNKY
                     PDKSIGILVPFNEQVTQVAKELRENNLTFEELGPNSLNKRKVINNIAYIIDFMLHCDD
                     VEKLIVVLNKVFIDTDNEEEIKYFLEELKNYSTEEIIYNFEFSKLDNDLIEFKEESDI
                     YLSFKRGIDIIKQILEYPIIRLDLLVLFIGKKLSLEKEDKAVLDYISFYIKYLVSENI
                     NMDLEDVYNLLFDVKNRVFNHIIDVVYEINGYEPEPGSITLCNYHKSKGMEWDCVFLL
                     GLVEYNFPDNINQKFQSDKWYLKEKYKNPMAIIKSEVEAILKGSISTDYAHKTKIDSI
                     NEKIRLLYVGITRAKEMLVLSGSAYRDESDIGNKRKEQKPCIYLSRLNQHIIEKRSN"
     gene            9554..10384
                     /locus_tag="PC512_001071"
     CDS             9554..10384
                     /locus_tag="PC512_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HDF2440838.1"
                     /translation="MNDKLKYFSYSQNSINTYKSCPLKFKYKYIDRINWKNDDVGSRE
                     YYETLKTGRDFHLICERYFSNIPLGIYFNEDDKNSKKFLKWMENIKKVVPIEKGKTYL
                     PEYEVRMTLNGDIIQAKYDLVVIGNNNIEIWDWKTESKKIDYKHVENRIQTIVYMFLA
                     KEVIPKVLKMDINVKDINMRYYQPEFDDLPITILYDEEKHEANRNKIQNYISMIKNTN
                     YEEHTYEDNLYNDIEKVYNKEERMCYRNKKHCKYCEFNKLCNGKEIDYSILEAEIYGT
                     "
     gene            10374..13841
                     /gene="addB"
                     /locus_tag="PC512_001072"
     CDS             10374..13841
                     /gene="addB"
                     /locus_tag="PC512_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddB"
                     /protein_id="HDF2440839.1"
                     /translation="MGLRFVLGRSGSGKSTYILDEIKKEAQKNETTSIILLVPEQYTF
                     EAENRVSKLFLGKEKDKYLRVRVLSFKTLSNIVFSQVGGLTDVNINSSGKAMMVYRAI
                     EDVSEELNVFSKSKSQSGFVSSITDMISEMKQYNISPEMLENISGELDNETLSLKLKD
                     ISKIYNSFEGKLHENYVDAQDMLTSLASKIELSSYLDGACVYIDEFTGFTPNQYNVIK
                     SILNKSKSVNISLTVDDINYIGYSKSDMFSRTKFTYSKLTQLCNEEGIKILPQVNLNT
                     GVIKRFEKVKELQHLERFYNAYPYKIYSNQTENIKIKEFNNLYSEVEEIAREIVHLVR
                     DKNVRYRDITIATRDLNRYDFLVHSIFNEYNIPNFIDKKREAKSNPIVILIISALEMK
                     NRRYGYETMFRYLKSGLIGIDNDDINLLENYVLANGIKGKKWFDEKWDYRITQSLSGQ
                     ESEFELELKEKINEIKNRVLEPIVILQEKLRGKNRVKEICRYIYEFLLDINMPETIES
                     LIINFKDKGELDVANQYSQVWDIVVDILDQMVELMGDEIISLEKFIKLITLGFDEYEL
                     GLVPPSIDQVLVSSVDRMKNPDTKYLYLVGTTDGVFPLITKDSGILSDNDRESLGNKG
                     IEVDIDSKTRSFEEQFLVYKALTSTSKNLTITYPISDHEGKTLRPSIIISRLKKIFPN
                     IENKSYLVEENKSTDKDILKKITVKSPTFNELINVIKNYDSDGYNTEEINSIWLDIYR
                     YYLKDEIYSSITKKVIKGLSYTNQVHKIEEKKIRSLYKSNSLSISRLEKYAECPFAYF
                     IQYGLKAKKRKEYSFTPPDLGTFIHNILDRFSKELLQDNLTWRDIDEKYIELKIGIIV
                     DEIILKIPGYILNSSERYKYLAYRLKNMLTTAITIISQQIKQGSFEPIDYEVKFGNNG
                     KYPPIKMVLENGQEVSLIGQIDRVDEFEEGENKYIRIIDYKSGNKSISLTEIYYGLQL
                     QLLVYLDAILESAKDEDININPAAILYCRINNPIAKFNEDKDDEEIQEAILKELRMKG
                     LVVKDSHIVKEMDKSLIDGERKNSLVIPVGLTKDGNVGKSTSAISYEDFKLLRKYVRH
                     AIKDLCEEMLSGEIRIAPYKHKDGTSCDFCDYSAICQFDSTIKDNKYKNLNNKSNEEI
                     IKMMKGDVN"
     gene            13841..17668
                     /gene="addA"
                     /locus_tag="PC512_001073"
     CDS             13841..17668
                     /gene="addA"
                     /locus_tag="PC512_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HDF2440840.1"
                     /translation="MSSPKWTKEQLEVIESRECNLLVAAAAGSGKTAVLVERIIQMIT
                     SRENPIDIDKLLVVTFTNAAASEMRERIGDAIGKALDENPENKHLQNQLVLLNKSSIT
                     TIHSFCLDVIKSNFHRINLDPNFRIGDQTECAILKQEAIEEVFEDLYEERDEGFLNLV
                     ESYAERGGDKEVQDIILGIYSFAMASPEPKKWLIDSAERFNIDENFDFSQSIWARAIL
                     DTVKIEINGLCLNMERALKEVESIEELETFAEKLSVEYKKIADISQACNKSWDEAYKK
                     MASMSFENYVKGVKRISKDAPSYIKESKEKAKTIRDKTKKSLESIVSATFNKDNDSIR
                     EEIKYLYNIVKPISSVVLRFEEEYSNKKREKGIIDFNDIEHFALNILTDVDEKGNIVP
                     SDIAVGYRNKFYEIFIDEYQDSNLVQEVLLKAVANTETPNRFMVGDVKQSIYRFRQAK
                     PELFLQKYNNYNDKKGSSHRKIMLYKNFRSREEVVDAVNYIFENIMNENIGEIEYTEK
                     ERLNLGANFNVDTDEKSIIGGATEIHLIQKDNKLDDDIINDKDDRINNKENEIEEEEK
                     LDNIQLEARMVGNIIKDLMKVNEDGKIQKVYDKGIDGYRPVEFRDIVILLRATSAWAP
                     VFADELMNMDIPTYADVGVGYFDTIEIKTILSLLQIIDNPMQDIPLISVLKSPIFGFT
                     PEDLIDIRVQSKDKIFYEVLKSTAEYDGFTDSQNENESEFIPSEECINKSKDFLIKLK
                     EFKEKSMYMSTDEFIWYLYTRTGYYAYVGALPGGSQRQANLKVLFERAKQFEETSLKG
                     IFNFVNFIEKLKKSSSDMGSAKTLGENANVVRIMSIHKSKGLEFPVVICSAMGKNFNT
                     QDFKKSILYHHNLGYGPQFVDYERRISFPSIAKEALKSKINIENLSEEMRVLYVAFTR
                     AKEKLIITGSTRNIQDSIKRWSNGIESLDTISQYEILKGKNFLDWIMPCVLRHRDLSN
                     LLEEVGLDAVFNVEHNSKWYGKLWNKSDILVEKKSDEEKESIEEILEKIDVDNPDSDY
                     YSEIEEKLNYIYPYEFSTRKPATISVTEIKKIQNNYEEELINTIFEQKVILKKPLFIQ
                     NEEEREKISGTERGTIVHLVMEVLDLKNVSSVNDIKSQIRGFVSKGIITEKQASIVNP
                     YKIYKFFASNIGKRMLNAEIINREKSIYAQVNMKDIYIYEKLINNDDKKLYDNESVML
                     RGIVDAYFEEDNQIVLVDYKTDFVNEENINQIIEKYKKQLDLYADIIETLTGKSVKEK
                     CIYLFGVDEAVCY"
     gene            17714..18925
                     /locus_tag="PC512_001074"
     CDS             17714..18925
                     /locus_tag="PC512_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HDF2440841.1"
                     /translation="MRFIHTSDWHLGKSLEGHSRIEEQAKFCEEFIKIVESNEIDMVI
                     IAGDVYDTSNPPAQAEKLFYQTVSRLANNGQRCVLIISGNHDNPERLSAITPLAHEQG
                     ILIYGYPLSATIEAKYKGFEITYATQGCTKLNINGENIVVATLPYPSEKRLNEVFSSE
                     DEFEKQKNYSEKVGDIFRSLEENFRSDTINIAVSHIFVIGGESTESERPIQLGGSFLV
                     ERKDLPEKAQYTALGHLHKQQKASERLNAYYSGSPLQYSKDERAYTKGAYIVDIKAGE
                     KPIIEDVYFNNYKPIEVFKCNGIEEALDICEQNQDREIWSYFEINTDEIISQNEIKKM
                     KELLKDIIEIKPIITSCYEQESVDIKEKSMAELFREFYSFSKGVEPKGELMDLFLDII
                     SEEGESADETN"
     gene            18912..22439
                     /locus_tag="PC512_001075"
     CDS             18912..22439
                     /locus_tag="PC512_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2440842.1"
                     /translation="MRPIRLELTGLNSYIDKQVIDFEKLIERGLFGIFGTTGSGKSTI
                     LDAITIAMYGNISRNTKEYINSVCDKAIISYEFEIGSKNTRRRYIVDRTIARSKTGTK
                     TSNARLIEVLNDNTQNVLADKVVEVNEKVAQVVGLTANDFTRSVVLPQDKFNEFLRLS
                     RADRRDMLERIFNLEKYGRSLGEKVKKRKNIQLQNLKDLKSKLSQYDGITEEVYNNIN
                     QELIELKNLEKDKNNALDLAQKSYEESKTVYEEQLKLEKNELRKNELDLKNSEIKEKI
                     ALVENDSNAKKVDPYISSVQNLEKKIDEDSFAVSNLEKKLAILNQELEVTKNRYEKIN
                     KIKNEEIPKLSEEKIRLQQAIKLEEELVLLDRELKELKESGINLNKTKVELEKVKQVS
                     ESRKDAVTKSIKEVEGKIDKVNISAELKQKIFLAYEYEKDYNNVLEEKNQKLNKLEEI
                     LKETENINLKVRYIDKDKNDVNRNLENLSLHLDVLLKKCPGKSADLLLKSEYVTELRN
                     KANNTKENEIKKSSIQDELKIILESKFNTEREVNLLNEKLENNRKNRDDLEKELEELK
                     YLNLASELRRELKENMPCPVCGSKHHENHDITKYDENISFVKEKLEKLEKEKISIRNN
                     IEELNAKVSGYLSIEKMKTKELEDVKGKLGGIPSSQLLKKLDEEQRKLALLKSNIQEW
                     EKEKESTENKVTLAKEEKNKIEKEELKIRESLNNYKKLTRDLNIEIEGLENKCKKLKQ
                     EYLGLKTITKVSNLLSKVKEIRENEKELELLSTGHSNLLKNRDSLDIKIRENESKLHE
                     IEIELIKARELYVEKKLSRDNKYKEVISITKGDLAKNLLHNVEENICKILEQEESSKK
                     KLEEQRLEYEKNIAEKHNIDGRLKTAKEQYKDQKSTLNKLLAENKFESIYAVKRALLD
                     TDAVKKLIEEILEHEEEQKLLSFKIKSSKEKLNGRSIKKEYFEQLKDEIYNLKVEIGN
                     ISKDIGANQNQLITLKDSLDKINDFNKQLKVVEHNVDLLEELDKCVQGNKFVEYVSTN
                     QLKYIALEASKRLDGITKGRYALEIDSTLNFVMRDNFNGGERRSIDTLSGGETFLTSL
                     SLALALSSQIQLKGSAPLEFFFLDEGFGSLDSELLEIVIESLERLHSNNLSVGIISHV
                     EELKNRVPVKLLVSSSEAGIGSKVKIEYS"
     gene            22570..23823
                     /locus_tag="PC512_001076"
     CDS             22570..23823
                     /locus_tag="PC512_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HDF2440843.1"
                     /translation="MLESPNNLIQIIFLIVLLIGSAFFSASETALMSLSKIRIRYMQD
                     EGVKGAKLVSSLIENPNKLLSSILVGNNVVNIAATSISTSLFIGLMGEKGVALATAVM
                     TVLVLIFGEITPKTIAANNSEKVSLLVSKPIKAIIFILRPIVWIFNIITNIIFKLFGI
                     TNKGAKSFITEEELKTMVNVSHEEGVLEMEEREIINNVFEFGDMQAKNAMVQRIDMVA
                     IDMEDSYDEIIQVFKTEKLSRMPVYEETIDDIVGILNIKDIIFLSDEEIESFDIKNYM
                     REPFFTYEFKKITQLLEEMKLEKSQMAIVVDEYGGTSGLLTIEDLVEVIVGDIEDEYD
                     EEEDEIQVIKEDEYIVDGSTKIGDVNELIGVNLESEEFDSIGGFIIGHLSRLPEENEV
                     IEVDNIRFCIESIEKNRIKKIRIYT"
     gene            23972..25024
                     /gene="ytvI"
                     /locus_tag="PC512_001077"
     CDS             23972..25024
                     /gene="ytvI"
                     /locus_tag="PC512_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YtvI"
                     /protein_id="HDF2440844.1"
                     /translation="MSILENNFLYKLKNNTIFFCIYTLLFIFIYKAFPYIAPFFLGAI
                     IALMINPISQKLENKFHINKGISTLVLSFLAVAIVSTVTTIIVINSMKELMGFLNNIS
                     ANPEDISNTIMYFLNKINDFMKSFQEIANFDVEQLVNKFSGEVMQITKNLLTSILGLA
                     TSIPYIIIFIITLFIATYFIAKDLDKIENSFYNMFTVDVRKKVKNVKKEAGLSLVGYI
                     RAYTILMAITFFAIWGSFALFGLKYGLIVGFVGALMDLIPFLGIITIYLPVIVYYFLI
                     KNYFIAISMTVIFFVLSLIREILEPKLVSVNVGLNPLATLAAIFIGIQVKGIIGVIFC
                     LGLVCMHDILKKVDIF"
     gene            25114..26340
                     /gene="pepT"
                     /locus_tag="PC512_001078"
     CDS             25114..26340
                     /gene="pepT"
                     /locus_tag="PC512_001078"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HDF2440845.1"
                     /translation="MKQKVVERFLKYVSFDTTSNSQCENCPSSEGQRVLAKYIVEELK
                     TMGVDDVSLDENSYIMATLKGNTDGVDTIGFISHLDTIEDVSGKDIKPKIIENYDGKD
                     IVLNEALNVITYVKDSPELEEFKGDDLIVTDGTTLLGSDDKAGIAEIVTAIEYLINHP
                     EIKHGDIKIGFTPDEEIGRGADLFDVEKFGAKYAYTLDGGIVGELECENFNAANATIT
                     IHGRNVHPGSAKNKMVNAIHIAAEISEMFPADERPETTEGYEGFWHLNSIGGNVENVS
                     MAYIIRDHCKEKFENRKSIMIENIEKINKKYDNRVELDLKDSYYNMKEKIEPVMFIVD
                     IAKEAMEELGIKPRLVPVRGGTDGARLSFNGLPCPNIFTGGLNFHGKNECIPVSSMEK
                     ATKLIVRIAEKYAERV"
     gene            26547..27599
                     /locus_tag="PC512_001079"
     CDS             26547..27599
                     /locus_tag="PC512_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp18"
                     /protein_id="HDF2440846.1"
                     /translation="MKIKSKKIIAFALSLGIMLPSCVYADNISKNQNAQVDMNNYLQG
                     RKSPKEEKLIGEDRFDTAIKISQSGWNNGSERVFLVNSNSLPDALASTPLASKLDAPI
                     LLTNKNSIPYNVTEEIKRLNPAEVILIGSEGAISSSVKESLEDMEVLVSRIGGADREE
                     TSLLLTRQLDDTGDLGVSKVAVVNGYNGLADATSISSPAASDNTAIIYTGKDSIRSEA
                     KNFITQNSTKTYIVGGEYSISKKLEGQLVNSERLAGTDRKDTNAKVLEKFYGKSSKVN
                     NMYFAKDGSGREADLVDGLAAGVLASKTKSPVVLASGSLSSAQKSFIKKVKADKFVQV
                     GGGKNSKPYAEALALQ"
     gene            complement(27852..28421)
                     /gene="yfcE"
                     /locus_tag="PC512_001080"
     CDS             complement(27852..28421)
                     /gene="yfcE"
                     /locus_tag="PC512_001080"
                     /EC_number="3.1.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphodiesterase"
                     /protein_id="HDF2440847.1"
                     /translation="MKIGIMSDTHGSLLYFEKALNVLSDCDVLLHGGDVLYHGPRNDI
                     PEGYNPKKFIETLNKLENIVIVKGNCDADVDQMVIEHPIQSPYVMSQFGEIRIILNHG
                     YIESEEEIIDKAKKMGGDILVLGHTHVKKLYMDDNLIVINPGSTSIPKDGSHSVAIID
                     IIKTDDEDELELDINLIDINTGNIININD"
     gene            complement(28446..29246)
                     /locus_tag="PC512_001081"
     CDS             complement(28446..29246)
                     /locus_tag="PC512_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+)/NADH kinase"
                     /protein_id="HDF2440848.1"
                     /translation="MKRIITINTNQLNKSLETKELLTRKLINAGFEVYSDIYPDTELI
                     ISIGGDGSFLRTVRDFDFPEIPIMGINTGHLGFFPDILPDKIDSFIEAYTKKDYIIQE
                     MSLLNAEVYTTTSGSNMLAVNEVVIRGDKSRTIHLNLSLDNKHIQNFSGDGMIISTST
                     GSTAYNYSAGGSIVDINLELMQITPLHPINTNAYRCFTSSIICSNESVIKIAPEYRFE
                     DSVLIVVDGVEHRFRQIENIKVSISDAKIKLLRMSNYEFWHRVSEKFL"
     gene            29381..30241
                     /locus_tag="PC512_001082"
     CDS             29381..30241
                     /locus_tag="PC512_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2440849.1"
                     /translation="MFSIRNITKKLGKFKLNNINLELKEGDIVGIIGPNGSGKTTLIK
                     IIMGIIDADEGEIELCNETIENSPISFKNNIGFVYDSLQFYPHLKVKEFRKIVSLFYK
                     NFDRERFDEYLNKFDIEENMHIENLSKGQSEKLMLSSALSHNAKLLILDEPTAGIDPI
                     VRTEIMQYLQDFVKNGSSSVIISTHNTDNLIKIADYLVFINRGNQIFTVKKELIEQEY
                     KIIRANKAELEAIKESIVGVKEYKYYNEALVKVGDSLKVKSLLIEIDKHKVKNPTIEE
                     LMYYYVNEVR"
     gene            30241..30927
                     /locus_tag="PC512_001083"
     CDS             30241..30927
                     /locus_tag="PC512_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HDF2440850.1"
                     /translation="MFNLIRKDLIIGISSDGIRNLKYILLFFVFYFFLNSISYYTVSI
                     VVSYLIFINTFECDYENDSRIFIRSMPVSIEDIVYSKYLLGVGLIISVTIIVSLLSKL
                     TSLVFFRNMVLNDVFFSVNIFLAILTILLPLIFKFGYGKMKVCGFIVSILIYFVYGSL
                     LKMISMIVYQVKHFNYSKVGGVYLSNYVTDIANTKYINLYSMTFLTIIIFIISMYFSI
                     KISKKNKFNY"
     gene            30979..31521
                     /locus_tag="PC512_001084"
     CDS             30979..31521
                     /locus_tag="PC512_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440851.1"
                     /translation="MKKFIKVSFFILGIFTLFIAINKLVYRDMVSVKDYEINHLEEIV
                     FDFDSRRSRDVGTIVRFKISNNSKYSYKLNSAKMKFENCVENKKGMNKCSAYVNVDLF
                     NEKNSITERTLKYGIKPNNQGYVDFVIPKGLNFDYRYFNESGMSVEYKGEYIVNIPMA
                     KGLYLVVGKNNDTWNANIME"
     gene            31600..32067
                     /locus_tag="PC512_001085"
     CDS             31600..32067
                     /locus_tag="PC512_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaK/EbsC family protein"
                     /protein_id="HDF2440852.1"
                     /translation="MSISNVREYFKQFGKEDSILEFEQSSATVELAAEAAGVIPARIA
                     KTLSFKIGDDAILIVTAGDAKIDNKKYKAEFNCKAKMLTPEEVLEFTGHAIGGVCPFG
                     LKNSIKVYLDDSMKRFDTVFPACGSSNSAIELTCEEMEKFSKCEKWVDVCKNW"
     gene            32776..33912
                     /locus_tag="PC512_001086"
     CDS             32776..33912
                     /locus_tag="PC512_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="HDF2440853.1"
                     /translation="MDLNSKKYQMLKELYVSFAENEVKPLATELDEEERFPYETVEKM
                     AKAGMMGIPYPKEYGGEGGDTVGYIMAVEELSRVCGTTGVILSAHTSLGSWPIYQYGN
                     EEQKQKFLRPLASGEKLGAFGLTEPNAGTDASGQQTTAVLDGDEYILNGSKIFITNAI
                     AGDIYVVMAMTDKSKGNKGISAFIVEKGTPGFSFGVKEKKMGIRGSATSELIFEDCRI
                     PKENLLGKEGQGFKIAMSTLDGGRIGIAAQALGLAQGALDETVKYVKERVQFGRPLSK
                     FQNTQFQLADMEVKVQAARHLVYQAAINKDLGKPYGVEAAMAKLFAAETAMEVTTKAV
                     QLHGGYGYTRDYPVERMMRDAKITEIYEGTSEVQRMVISGKLLK"
     gene            33971..34753
                     /locus_tag="PC512_001087"
     CDS             33971..34753
                     /locus_tag="PC512_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009524639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HDF2440854.1"
                     /translation="MNIVVCIKQVPDTTEVKLDPNTGTLIRDGVPSIINPDDKAGLEE
                     AIKLKEEMGAHVTVITMGPPQADMALKEALAMGADRGILLTDRAFAGADTWATSSALA
                     GALKNIDFDIIIAGRQAIDGDTAQVGPQIAEHLNLPSITYAEEIKTEGEYVLVKRQFE
                     DCCHDLKVKMPCLITTLKDMNTPRYMKVGRIYDAFENDVVETWTVKDIEVDPSNLGLK
                     GSPTSVFKSFTKSVKPAGTIYNEDAKTSAGIIIDKLKEKYII"
     gene            34772..35782
                     /locus_tag="PC512_001088"
     CDS             34772..35782
                     /locus_tag="PC512_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HDF2440855.1"
                     /translation="MGNVLVVIEQRENVIQTVSLELLGKATEIAKDYDTKVSALLLGS
                     KVEGLIDTLAHYGADEVIVVDDEALAVYTTEPYTKAAYEAIKAADPIVVLFGATSIGR
                     DLAPRVSARIHTGLTADCTGLAVAEDTKLLLMTRPAFGGNIMATIVCKDFRPQMSTVR
                     PGVMKKNEPDETKEAVINRFKVEFNDADKLVQVVQVIKEAKKQVKIEDAKILVSAGRG
                     MGGKENLDILYELAEIIGGEVSGSRATIDAGWLDKARQVGQTGKTVRPDLYIACGISG
                     AIQHIAGMEDAEFIVAINKNPEAPIFKYADVGIVGDVHKVLPELISQLSVAKEKGEVL
                     AN"
     gene            35801..36598
                     /locus_tag="PC512_001089"
     CDS             35801..36598
                     /locus_tag="PC512_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="HDF2440856.1"
                     /translation="MSTSDVKVYENVAVEVDGNICTVKMNRPKALNAINSKTLEELYE
                     VFVDINNDETIDVVILTGEGKAFVAGADIAYMKDLDAVAAKDFSILGAKAFGEIENSK
                     KVVIAAVNGFALGGGCELAMACDIRIASAKAKFGQPEVTLGITPGYGGTQRLTRLVGM
                     AKAKELIFTGQVIKADEAEKIGLVNRVVEPDILIEEVEKLAKIIAKNAQLAVRYSKEA
                     IQLGAQTDINTGIDIESNLFGLCFSTKDQKEGMSAFVEKREANFIKG"
     gene            36696..37541
                     /locus_tag="PC512_001090"
     CDS             36696..37541
                     /locus_tag="PC512_001090"
                     /EC_number="1.1.1.157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyryl-CoA dehydrogenase"
                     /protein_id="HDF2440857.1"
                     /translation="MKLAVIGSGTMGSGIVQTFASCGHDVCLKSRTQGAIDKCLALLD
                     KNLTKLVTKGKMDEATKAEILSHVSSTTNYEDLKDMDLIIEASVEDMNIKKDVFKLLD
                     ELCKEDTILATNTSSLSITEIASSTKRPDKVIGMHFFNPVPMMKLVEVISGQLTSKVT
                     FDTVFELSKSINKVPVDVSESPGFVVNRILIPMINEAVGIYADGVASKEEIDEAMKLG
                     ANHPMGPLALGDLIGLDVVLAIMNVLYTEFGDTKYRPHPLLAKMVRANQLGRKTKIGF
                     YDYNK"
     gene            37628..38803
                     /locus_tag="PC512_001091"
     CDS             37628..38803
                     /locus_tag="PC512_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HDF2440858.1"
                     /translation="MREVVIASAARTAVGSFGGAFKSVSAVELGVTAAKEAIKRANIT
                     PDMIDESLLGGVLTAGLGQNIARQIALGAGIPVEKPAMTINIVCGSGLRSVSMASQLI
                     ALGDADIMLVGGAENMSMSPYLVPSARYGARMGDAAFVDSMIKDGLSDIFNNYHMGIT
                     AENIAEQWNITREEQDELALASQNKAEKAQAEGKFDEEIVPVVIKGRKGDTVVDKDEY
                     IKPGTTMEKLAKLRPAFKKDGTVTAGNASGINDGAAMLVVMAKEKAEELGIEPLATIV
                     SYGTAGVDPKIMGYGPVPATKKALEAANMTIEDIDLVEANEAFAAQSVAVIRDLNIDM
                     NKVNVNGGAIAIGHPIGCSGARILTTLLYEMKRRDAKTGLATLCIGGGMGTTLIVKR"
     gene            38999..39901
                     /locus_tag="PC512_001092"
     CDS             38999..39901
                     /locus_tag="PC512_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HDF2440859.1"
                     /translation="MFKKENQRYNLISYTNEEEMTLKEVLLDKLNFSVRSLSKMKREK
                     SVLVNGVYKKPSLKVYSGDLIEVKIDEEKANFEPQDLNLQIIYDDFDIIMVNKPPFMV
                     VHPTKSHYDKTIANGISYYIDNQKENVKIRFVNRLDMNTSGLVIVAKNAYAHHTLSTA
                     MSENKVEKKYITVVDGIIKENEGTIDEPIYRPTEDSIKRIIDERGQSSVTHYKVIERL
                     ENATVLEVSLETGRTHQIRVHMAHIGHGIIGDELYGYVDEDLINRQALHAYKLEFEQP
                     RTKEKLKFKADIPEDMKELISKLR"
     gene            39915..40919
                     /locus_tag="PC512_001093"
     CDS             39915..40919
                     /locus_tag="PC512_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HDF2440860.1"
                     /translation="MIIHKFIIHVLDKNSDVPILNDFEGKVNQEVDGFFQKAIKRIAK
                     DEDLRKGVFKDYNDNLIKNCCEQIIYDESTFLKNSKEIASYLFDVMKINAALESCDLA
                     ICLYTIKDEKSVAILKLDYKKLYTHSIEFVDDKFNIQMVSNEIGIPETLRQKQGALIS
                     LSGINDEFHLRLLDKDAEKEGSESKFVTEFLNAKKIDDDKYKTKVFKNTAENWITNAL
                     SNDIKQAEDVRSILNYTLKEKHEVDINDFVDNSIKDDELKDSFKEHMEEKGLDESFSI
                     DKKWVEKKLKKRSIKTDNGFDIKGNLTDFEDPMKYTVKQNQDGTIDIIIKNVTFYEEK
                     "
     gene            complement(41063..41290)
                     /gene="acpP"
                     /locus_tag="PC512_001094"
     CDS             complement(41063..41290)
                     /gene="acpP"
                     /locus_tag="PC512_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HDF2440861.1"
                     /translation="MFEKIKEIIAEQLGVDNLDEITMEASLMDDLEADSLDAVEIIMA
                     LEDEFGIEIPDEEAENFKCIGDICKYIEENK"
     gene            41462..41887
                     /locus_tag="PC512_001095"
     CDS             41462..41887
                     /locus_tag="PC512_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440862.1"
                     /translation="MKYVGLLLTSVGMFLLIAVNFYYNSITLDMQRIEDYVMETNLIL
                     EDVAEKESYVSNEKEDYISRLMHVKKGIENSKTSFLIERYKEYKIKSIESLIYTISEE
                     KKDYLDEVDRYNKLGEKEINKLINKNFLEVTYLSITTYI"
     gene            41935..42141
                     /locus_tag="PC512_001096"
     CDS             41935..42141
                     /locus_tag="PC512_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440863.1"
                     /translation="MTKLEDNMERFFGGCEGFFGNKMLIIIVIVFLLLCTDILEDLLC
                     DDNIWIWVILIVLLLFNFDDGCCC"
     gene            42323..42502
                     /locus_tag="PC512_001097"
     CDS             42323..42502
                     /locus_tag="PC512_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440864.1"
                     /translation="MLDRFFGEEGCFGGGGWWIIVLFFLFLAFGDSWAEFDIMAWIPF
                     LIVLLILCCCGGCLE"
     gene            42536..42736
                     /locus_tag="PC512_001098"
     CDS             42536..42736
                     /locus_tag="PC512_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440865.1"
                     /translation="MLDRFFGEEGCFGGGGWWIIVLFFLFLAFEDCWRDIDIMSWIPF
                     LILLLITCSCGGFFDGEVGCGC"
     gene            42989..44005
                     /gene="ccpA"
                     /locus_tag="PC512_001099"
     CDS             42989..44005
                     /gene="ccpA"
                     /locus_tag="PC512_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator CcpA"
                     /protein_id="HDF2440866.1"
                     /translation="MKGNITIKDVAKQAGVSISTVSRVINDSKPVTDEVKQKVLEVIK
                     ETGYIPNPLARSLVTKKSQLIGVIVPEVSDSFVNEVLNGIEEVAKMYDYDILLANTYS
                     DKEQELKSINLLRAKQVEGIVMISWIVEQEHINYIQNCGIPATYISKTARNYDIYTVS
                     TSNEEATFDMTEHLIKKGHEKIAFIMTSKDDTVLEMERLAGYEKALSNNNIELDKSLI
                     KYGGTDYESGYNSMKELLDDGIIPHAAFVTGDEAAIGAINAICDAGYKVPEDISVAGF
                     NDVKIARMYRPKLTTVYQPLYDMGAVAIRMVIKLINKELIENKKIELPYRIVDRESVT
                     ERKK"
     gene            complement(44128..44526)
                     /locus_tag="PC512_001100"
     CDS             complement(44128..44526)
                     /locus_tag="PC512_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440867.1"
                     /translation="MKKLDTESLEKMAKQKNIDKDKIEKMADSYKGKSENELMEELIK
                     IGKNLDGRDEVVSKFKAFLDENQRKKLDNIMEKISDAENQRDTKPAKTKKAKPTKGKS
                     NSPAPKNTPGSQQKKSKSLFKKTKKSNPHE"
     gene            44738..45643
                     /locus_tag="PC512_001101"
     CDS             44738..45643
                     /locus_tag="PC512_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440868.1"
                     /translation="MNNLLFLIGVIALSNGNISIFDDKNKSKGNNRVRKNKKNANDKL
                     SQSTHGNLRFDANDIKRGLRLMDLSEEDLEMGMEIITRTKKYMSRDERKILIKIESVL
                     DLVRGIKKLNNIDMVDTEDETDFFRKMDSDDKKNMMIKEIIDVFPEKRKNSVEKAIGM
                     KKKIDLFAELFLPDDFGEGGFSLSSLANINNLGSMNNLKLLGSLLRGDDSNNDDEDNN
                     DELNYEDEELDCEDKELDDDELTDEGEMEDNEDELVEDKNTGYENIENDEDIVYDEEL
                     YNINEQESEYNYNEKNTKTRAKKKR"
     gene            45758..45938
                     /gene="ssrS"
                     /locus_tag="PC512_001102"
     ncRNA           45758..45938
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="PC512_001102"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            46121..47338
                     /gene="cdeC"
                     /locus_tag="PC512_001103"
     CDS             46121..47338
                     /gene="cdeC"
                     /locus_tag="PC512_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium morphogenetic protein CdeC"
                     /protein_id="HDF2440869.1"
                     /translation="MQDYKKNKRRMMNQPMSTMNEEEVYTDEINSEDMRGFKKSHHHN
                     GCNTDNKCECHDDCNPCNPCNPCKPNPCNPCKPNPCDDNCGCHDNCKCDCEPCEMDSD
                     ECFENKCGPECCNPISPRNFSVSNAVPFAIEANRIFDTMQFQTFTDATGPNGEPLTFE
                     TEVVEVFGSVPSAGQASVTIEKICLSNDGIVIDTGMTTLEDFDLDPLGDIVGRNCETT
                     FEFAVCGERNSECCRQGKGKSVAYKQRGLTVAVRNLVLELRGRCGCTEFVALAFPAVR
                     AGGGCKRRVDYVEFTFNTLSAPICLPADGRAVTLRQEYQTNLTVDCIGKSILKLECNE
                     CCEPFYELIIPNDIDLVLCLQETVSTLISEQIVVLASPNPIQPRLVDTFSKVCDFSQC
                     GPNHGSGKPSCHR"
     gene            complement(47438..48760)
                     /locus_tag="PC512_001104"
     CDS             complement(47438..48760)
                     /locus_tag="PC512_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HDF2440870.1"
                     /translation="MKVPYLVLSTVILFISNFIVRIFGFLYKIFLSRALGETGLGIYH
                     MIFNFLMICLAVTTTGIPTALSCLVAKRKALNDRHNTNALFISTLYISFFVALIISIV
                     ASFNSSFLSLKFLKDAKLNLFILAVCPAIVIITLSNVLRGYYYGIKNVKIPAIGQIIE
                     QIGKILFVFLLVMYINNKSMNCYIALLGISIGELSNIIFMLICLWRDSSFDNRYIISI
                     KDFYNSSMETLKMSIPITCNRMSNILLQSISSMMIPSRLALSGMTYQQSLSMYGIVSG
                     MVMPFIFLPFTVGSALIVNLIPTISQEMALRKRKSVIKKIKYSILLTLFVGILSSIFF
                     YFFGKDLCILVFKNTLAGEYLKAMFLVPLFMSLNQTLSGILHSIRKELASSINTITGM
                     LIQLIALYVFLPIPGLNIYAYIYTMTIVSIFTCLLHTIVLFKSLKSIR"
     gene            complement(48811..49605)
                     /locus_tag="PC512_001105"
     CDS             complement(48811..49605)
                     /locus_tag="PC512_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ family protein"
                     /protein_id="HDF2440871.1"
                     /translation="MFYDYHMHSSFSTDGKSTMEEMVKKSIELGLEEICFTDHVDYDV
                     YADDSFSIVYEDYFKSLETLQSKYKDKISIKKGIEFGVQTQLMDTYKKEAHQYPLDFI
                     ICSIHAIDTMDLYLGNYFKDKTQHEVYENYYLYLYNIVKNYKDYSVLGHLDLIKRYAP
                     YDTILDDRLFSDIIEETLKQAIYDGKGIEINTSCYRYNLPDLTPSKYILQMYKDLGGE
                     IITTGSDSHHISQVACEFDYIYSLLKNMGFKYVSKFNKLKPEFIKL"
     gene            49715..51160
                     /locus_tag="PC512_001106"
     CDS             49715..51160
                     /locus_tag="PC512_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDF2440872.1"
                     /translation="MEKYRIDLNEKKSTKYIQIFNHIKELIINKELVEHEKLPPIRKL
                     SNFLQVNNTTIVKVYELLENEGYVYKIIGSGTFVSSLNSYKSGIDNRKNKIIVQREDL
                     IHFDNGNPSNDMFPIDSFKNAVNMALSKDGSSIFEYDEGLGSEELREKMVEYLSDGNI
                     KTTKENIQIISGAQQGIDIVCKGLISYSDVVFMEEPSYNGAIEVFKSRGAKIISIPML
                     DDGIDIGILKLKLEKIKPRLIYIMPNFQNPTGISYSTYKKKKLIELAEEHDFYIIEDD
                     FISDFVFESKDNRTIRSYDDKNRVVYIKSFSKILMPGLRIGIVEMPNELLKKVLWAKY
                     SSDISTPGLIQKSMYYYMNNFDWKNYLSHIEKIYTDKYKLAKNLINDKLSGKLKVRKS
                     CGGINFFLELPRGYTSQAFTNFMLNKGVSMLPGTYFFDNLVDDRFFRINIARPSMEEL
                     EKGISIISDNIDEFFCEYKNKLDIKSNKLFY"
     gene            51189..51398
                     /locus_tag="PC512_001107"
     CDS             51189..51398
                     /locus_tag="PC512_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 domain-containing protein"
                     /protein_id="HDF2440873.1"
                     /translation="MFDKKKLDRINELAKKNKEGILSADEIKEREILRKEYLENFRAH
                     FRSRLDSVKVVSPEEYEQYMKNNKN"
     gene            51418..52812
                     /locus_tag="PC512_001108"
     CDS             51418..52812
                     /locus_tag="PC512_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HDF2440874.1"
                     /translation="MNLKYEFKNAWDFERKENTIEQIMQYSSNYMEFLSKSKTERLSV
                     KEIIKLAKENNYISIDEAMEKGSISCGDKIYVINKEKAVALFVIGKNYIEKGMKIIGS
                     HIDSPRLDLKPNPLYQESNLGFFKTHYYGGIKKYQWTAIPLALHGIVILNDGTKVDIS
                     IGEEDSDPVFCVTDLLIHLAGDQMQKKLSEGISGEALNILIGNMPLEDEEKEPITANI
                     LKILNEKYNIVEEDLLSAEIEVVPAGKARDLGLDRSMVLGYGHDDRVCSYAAVKAILE
                     TEQPEFTSVALCVDKEEIGSKGNTGMHSKFFENTVAELIALEGDYCDIKVRRALANSK
                     VLSADVSAGYDPNFGEAYEKRNSAYMGNGVVLTKYTGSRGKSGCNDANAEFMSEVKRI
                     FNKGNVVWQTAELGKVDQGGGGTIAHILANQGAEVIDCGVGVLNMHAPHEIVSKVDIY
                     EMYKGYKAFFNINL"
     gene            53052..53237
                     /locus_tag="PC512_001109"
                     /pseudo
     CDS             53052..53237
                     /locus_tag="PC512_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896033.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
     gene            complement(53346..54512)
                     /locus_tag="PC512_001110"
     CDS             complement(53346..54512)
                     /locus_tag="PC512_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017752472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDF2440875.1"
                     /translation="MKGGVRKRGKKWYYYFDAGIVDGKRKKVERVGGNTKKEAEKSLR
                     DAINEYENAGIVFDETNMSLSDYLNFWYKEYVLLNCKYNTQESYRNLIENHIEPRLGK
                     CKLKSINPAIIQEFLNNKSKETYTQNGEEKHYTKGVLKAIYVVLNAALKSAVYPYKLI
                     KENPVQYASIPKNVLKVKNESDNKTITLDEFNKILEIYPKNTNIYIPLLIGFHTGMRK
                     GEILGLCWDNVDLDNNIIKVRKNLIKRKVSEFELASPKTKTSIRDIKIGDTLSRILKE
                     EKLNQKKQKIKIGKWYKETEYDWVCRKKDGSFVNHNNIDAAIRTINKKLNINFNFHCL
                     RHTHATLLLENGANVKYIQQRLGHSQLSTTMDTYSHVTSKMESETIDILEGILQ"
     gene            complement(54650..54856)
                     /locus_tag="PC512_001111"
     CDS             complement(54650..54856)
                     /locus_tag="PC512_001111"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440876.1"
                     /translation="MNLSFNKKKKFELSKEELELIENWLGNKYAGDMTIPAIVDFSLE
                     TDIEYEKIVVYLAEKVLESRDKKH"
     gene            complement(54915..55136)
                     /locus_tag="PC512_001112"
     CDS             complement(54915..55136)
                     /locus_tag="PC512_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2440877.1"
                     /translation="MLKELRKKKKLTQIELAKRVGCHRSQISRLENNEDKDLTIPILI
                     ELEIALGLEEKYLVNYFADEYIKKRKLHK"
     gene            55420..55557
                     /locus_tag="PC512_001113"
     CDS             55420..55557
                     /locus_tag="PC512_001113"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440878.1"
                     /translation="MNKTKYYDILKLNLLMKKLKELDKNKINEYKIKVKEIHKINKKE
                     E"
     gene            complement(55594..55989)
                     /locus_tag="PC512_001114"
     CDS             complement(55594..55989)
                     /locus_tag="PC512_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2440879.1"
                     /translation="MNRIKELREEKGISLDKLSEDLHINKSTLSRIENGLREPKKSTI
                     EEYANYFDVSTDYLLGRTDVRNSLFINKNEKDYDAENFKTEKELIENMYLDEDMKEVF
                     NIFSELSPDAREKALKVAELFLLDEKNKK"
     gene            56168..56431
                     /locus_tag="PC512_001115"
     CDS             56168..56431
                     /locus_tag="PC512_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDF2440880.1"
                     /translation="MYLNRLEGLMKENRHTQKNVADILGLSSYGFRLKLKGKNEFKAS
                     EIKKISKLYNVSADYFFSDEVAKIAIKEERGNNNEESNHNQAK"
     gene            56400..>56929
                     /locus_tag="PC512_001116"
     CDS             56400..>56929
                     /locus_tag="PC512_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HDF2440881.1"
                     /translation="MKNLTIIKQNNQFLVESREVAELIEKKHDNLLRDIRGYKKILED
                     SSNLRSQDFFIESTYINTQNKIQPCYLLTKKGCDMVANKMTGEKGIIFTAIYVTKFEE
                     MEQELKEQQPKLPTTYKEALQQLLIEVEEKEQLQLENQEKDKVIQLQQPKVLFADSVA
                     SSDNSILVGELAKLLR"
BASE COUNT        23067 a         6061 c         9881 g        17920 t
ORIGIN      
        1 gatatatatg tagtttttag agtgctaact ctaaaaaatt agttttacta atttataaaa
       61 atttaatgcg ggtgtagctc aatggtagag ttctggcctt ccaagccagc tgtgagggtt
      121 cgatcccctt cacccgctcc aaaagattat gtggttacaa tagcagagag gatacacctg
      181 ttcccattcc gaacacagaa gttaagctct ctagcgctga tggtacttgg tgggaaactg
      241 cctgggagag taggacgtag ccacgtaatc tttttttgtt gtattaaatt taataaacct
      301 acaattgtta tatgttttta tttgtctttt atagattttt ttggcaataa atgatatagt
      361 gaagataatt aaatatattc aatatattta atttttttat tttttgtttt tataattttt
      421 ttagaagttt attttttatg tacttattta taattttggg taaaaacact ttgatataat
      481 ttcaaaaatt aaaaggttaa aaaacaaagt agaaatttat gttaaataag gagattaata
      541 tgagaagaaa tacaaaatta ttaacaacag ggattctttc aatggcaatc gtcgcaccta
      601 caatggcatt tgctactgaa tctaatgcta tggaaaataa cgctgattta aatataaact
      661 tagagaaaaa aagtatcgtt ttaggtagta cctcaaaagt cagtgttaag tttaaagaaa
      721 aaccagatgc agatagcatt acattaaagt ataaatgcta tgatatgcca ttggatacaa
      781 ctttaaacta caatcaatca actgagtcat atgaaggaac tatcaattat aataaagacc
      841 cagaatatct aaatgtttgg gaactacaag ggataacaat aaacagcaaa aataatccta
      901 aaactttaaa caaacaagaa ctagaaaaga tgggattaaa tttaaaagac tataatgtaa
      961 cacaggaatg tataattgaa gatataactt ctagaaaaga tgtaaataaa tatttaagaa
     1021 aaacttctgc acctattaca gaacttacag gaagtgatag atacgaaaca gcagttaaaa
     1081 taagtaaaga aggctggaaa aatggttcag ataaggtagt tataataaat ggggatgtaa
     1141 gtatagatgg cattatatca actccactag caactacata taatgcgcca atacttttgg
     1201 ttgaaaaaaa caatgtacct aatagtgtaa aatcagaatt aaagcgttta aatcctaggg
     1261 atgtaattat aattggagat gagaatgcta tttctaaaac tactgctaat caaattaaat
     1321 cgactgtaaa tgctagtcaa acacgtctaa agggctctaa tagatatgag acatctttat
     1381 tgatagcaaa ggaaatagat aaaaatcatg atgtggaaaa agtgtacata acaaatgcta
     1441 atggcggaga agtggatgca cttactatag cagcaaaagc aggtcaagac aagcaaccaa
     1501 ttatattaac tgataaaaat agtattacag acaacacata taaatggtta aagagtgagg
     1561 atttacaaaa tgcttatttt ataggtggcc ctcaaatgat atcaacaaat gttataaata
     1621 aggtaaatga tataactaaa gataatgtta ctaataatag agtatatgga gcagatagac
     1681 acgaaacaaa tgcaaacgta ataaaaaaat tctatacaga tgatgagcta gaggctgttt
     1741 tagtagctaa atcagatgta cttgttgatg ctttagcagc aggtccattg gctgccaact
     1801 taaaatctcc aatacttata acaccaaaga cgtatgtatc tgcataccat aaagaaaact
     1861 tagaagctaa atcggctaat aaggtatata aaataggagg aggattgact tctaaggtaa
     1921 tgaactctat agcatcatca ttatctaaac acaatacgac tccaacagaa ccaggaaata
     1981 gtgggggtaa gacagttatg attgacccag gacatggtgg ttcggacact ggaacaacag
     2041 gtaaaccatt agggggtatt aaagaaaaag actatacatt aaatacttca cttgcgacaa
     2101 ctgaatattt acgttcaaag ggattcaatg taataatgac aagagataca gataagactt
     2161 tatctcttgg aaatagaact gctttatcta actctttgag accagattta tttacgagta
     2221 tacactataa tgcatctgat acaactggga atggtgtaga agtattttat aagcttaaag
     2281 ataaagatgg aggaactact aagactgtag ctacaaatat attaaataga atcttagaga
     2341 aatttaatct aaaaaataga ggtgcaaaaa caagaacact atcaactgac cctacaaaag
     2401 attatttata tgttttaaga aataatgata tgccagctgt acttgtagaa tgtgcatttt
     2461 tggataatga gaaagatatg agtttactta atacatcaaa taaagtaaaa gaaatgggta
     2521 cacaaatagg taaaggcata gaagattcat taaaatagtc tacaatgaga gcatagaaaa
     2581 atttaaaata aattaatcta taattttaaa tttaaactaa agctataaga taagaatgta
     2641 attataatag taataaagac tgtatataca ttgtgcatat aaatgcgaaa tgaggtatat
     2701 acagtctttt tataattaat tgtaaaatga tttatgttat atgaaaaatt tacatatatt
     2761 aaggctacag ttaattgtca agagctggag tattcatttg taatacacaa tataagctta
     2821 attactatat tttattgtgt gttttttgtg gatttttatg tcaataaatg atatagtata
     2881 gataattaaa tgtattaaat atatttaatt tttttatttt ttgagtttta taagtttatt
     2941 tttatatatt acttatatat tacttatata ttatttatat tttgggttag atacactttg
     3001 acatattttc aaaagttaaa agattaaaaa taaagtagaa atttatgtta agtaaggaga
     3061 ttaatatgag aagaaataca aaattattaa caacagggat tctttcaatg gcaatcgtcg
     3121 cacctacaat ggcatttgct actgaatcta atgctatgga aaataacgct gatttaaata
     3181 taaacttaga gaaaaaaagt atcgttttag gtagcaaatc aaaagttagt gtcaaattta
     3241 aagaaaaacc agatgcagat agcattacat taaagtataa atgctatgac atgccattgg
     3301 atacaactct aaattacaat caatcaactg gggcatatga aggaactatc aattataacc
     3361 aagacccaga atatctaaat gtttgggaac tacaagggat aacaataaac agcaaaaata
     3421 atcctaaaac tttaaacaga caagacctag aaaagctggg attaaattta aaagactata
     3481 atgtaacaca ggaatgtata attgaagaca taacttctag aaaagatgta aataaatatt
     3541 tgagaaaaac ttcttcacct attacagaac ttacaggaag tgatagatat gaaacagcag
     3601 ttaaaataag taaagagggt tggaaaaatg gttcagataa agtagttata ataaatgggg
     3661 atgtaagtat agatggcatt atatcaactc cactggcaac cacatataat gctccaatac
     3721 ttttggttga aaaaaacaat gtgcctaata gtgtaaaatc agaattaaag cgcctaaacc
     3781 ctaaagatat aattataatt ggagatgaga atgctatttc taaaactact gctaatcaaa
     3841 ttaaatcaac tgtaaatgct agtcaaacac gtttaaatgg ttctaataga tatgagacat
     3901 ctttattgat agcaaaggaa atagataaaa atcatgatgt ggaaaaaata tacataacaa
     3961 atgctaatgg cggagaagtg gatgcactta ctatagcagc aaaagcaggt caagacaagc
     4021 aaccaattat attaactgat aaagatagta ttacagacaa tacatataaa tggttaaaga
     4081 gtgaggattt acaaaatgct tattttatag gtggtcctca aatgatatca acaaatgtta
     4141 taaataaggt aaatggaata actaaggata gtgttactaa taatagagta tacggagcag
     4201 atagacacga aacaaatgca aacgtaataa aaaaattcta tacagatgat gagttagagg
     4261 ctgttttagt agctaaatca gatgtacttg ttgatgcttt agcagcaggt ccattggctg
     4321 cgaacttaaa atctccaata cttataacac caaagacgta tgtatctgca taccataaag
     4381 ataatttaga agctaaatca gctaataaag tatacaaaat aggaggagga ttgacttcta
     4441 aggtaatgag ctctatagca tcatcattat ctaaacacaa tacgactcca acagaaccag
     4501 gaaatagtgg gggcaagaca gttatgattg acccagggca tggtggttca gcacctggaa
     4561 attcatctgg aggaatgatt gaaaaagatt acaatttaaa tacttcactt gcaacaactg
     4621 aatatttacg ttcaaaggga ttcaatgtaa taatgacaag agacacagat aagactttat
     4681 ctcttggaaa tagaactgct ctatctaatt cattgaaacc agatttattt acaagtatac
     4741 attataatgg ctcaactaat aaacaaggtc atggtgtaga agtattttat aagcttaaag
     4801 ataaaaatgg agggactact aaaactgtag ctaccaatat attaaataga attttagaga
     4861 aatttaaact tacaaataga ggtataaaaa caagagtact tcctagtgat tctacaaaag
     4921 attatttata cgttttaaga agtaatgata tgccagctgt acttgtagaa tgtgcatttt
     4981 tggataatga aaatgatatg agtttaataa actcatctgc aaaagtaaaa gaaatgggta
     5041 cacaaatagg taaaggaata gaagattcat taaaataaat ggaaataaaa atatttaaaa
     5101 acttaatgta aatttatagt tgtaaattta tactaaagtc aaaaaatgaa atataagtgt
     5161 atcaatagta agactgtatg tacatttgca catgtgaatg caagtatata tacagtcttt
     5221 ttttgtagtt aaatgcaata atttgattgt gttttgtaaa atacacaata tgatataatt
     5281 agataatata cacttaattt aattgaggaa ggtgattata tggaatattt atttgaaaaa
     5341 agtagtttaa aagaatatgg aaatgaagct ttagataaat atagagaatt attagataaa
     5401 actggtaata attcaaggtg tattcttttg ttagtaccaa acaataacac aaagatacga
     5461 tatgaaaggg ctctaagatt aaattatagt gaagaactga aagtaacaac atatataagt
     5521 tttgtgaaga aagaattagt taaatactgg ccactaataa tagaaaaatg tgatggaata
     5581 agtacaaagg ttgtatctcc aacatttata tcaaatagtt taagtgaata tttaatagtg
     5641 caaaaagtta aggaaaaaag gatacaagaa ggatattttg aagatattac aggaaccaat
     5701 aaatccatag caaatagtat aatgactaac ataaataagt ctgcatttaa tttaattgat
     5761 tttgatttta ttggagaaaa aatatattca tcaaagaaaa ataaagatag tatatataga
     5821 ttttcataca ctcaaatgga tgaaattata tcatattata taaattcctt actatcaaat
     5881 tcaattttag ataatgcatt aagcatatat ttatacaatc aatacctact taatgatgat
     5941 ttttatttaa aaaacttatt tacagaagtg agatatataa ttgtggatag ccttgaaagc
     6001 tcaagtaatg cagaagttga ttttataaca gaagcattgg ataatacatt acaaagttat
     6061 atatattttg attatagtag ggattattct gtatttaata atgtggatat agactatata
     6121 aatgagaaaa taatatcaaa aattaagcct aaagaagaaa atattaaaaa gaaggagatt
     6181 agaatagaag atttatactt attacctgca aatatagaat taaatcaatc aagtcaatta
     6241 tataatgaaa tgttagattt aataagtgaa aaagttatat ctcttataga agaagatgta
     6301 tctccaagag atatagcaat tatatctcct ataaacaata gtatattgga gcatcaaatt
     6361 agagattctt tgatagaaaa aaatatagat gtttttagta ctaagaagga taaaaaagct
     6421 gtggattatc catatgggaa tgcattggta gtggctacat gtatattcta tggatattta
     6481 gattttataa aagatgatga atacttaagc tttttagaaa ctcttttaga aataaatagg
     6541 ataaaagcat ttaagatttt taatgaaaca agacatttaa gtattgataa tatagatgaa
     6601 catagtcagt atcgtgatat tttacagtat attgaagaaa aaaagaagag tgatataaaa
     6661 atacatgaat ttttaactca attttacata gataaaatgt taaatttaaa agaaggtaaa
     6721 aagaatgttg ggttatgtaa aaagataata gctgaaagtg agtcttttag tgaaagttta
     6781 agtctacttg ggatgaaaaa agaaaagata tttgtagaag ctttaaaaag tacaataaac
     6841 gattattact ctgttgtcga tatagaagag ttgaaatcca aagacaaaat agtaataact
     6901 actccttatt catatatatc atcaaatata gatagaagta tacaaatatg ggtagatata
     6961 ggaagtaatg cttggaatat gaaaatagaa aaagatataa gtaatttaat tgtacttaga
     7021 aaatcttttg aagaaaaaaa gatttataca aatgaaatgg aagaatatta taaaaaatat
     7081 tatctataca atacagtata taatttgtta ttaaatgcaa agaaaatcta tgcatttaaa
     7141 agtgaatatg cgattaatgg ttatatccaa gagagtatat tatatagtat acttttaaaa
     7201 atctcacata aaggagataa aaattatgat taatataaat tatagagaag accagatacc
     7261 aataataaat tacgataatg gtactatggc agtaccagca gtaccaggtg ctggaaaaac
     7321 atttataata acaaatttag tagctaaact attacttgaa cagaaacata agagtggtaa
     7381 aatattaatt cttacatata tgaatagtgc tgtaaataat tttaaaggta gaataagaaa
     7441 gattcttgaa gagaataaaa tagatgatac taattcgtat gaagtaatga ctatacacag
     7501 tttggctgta aaaataataa aggaaaagcc agaagttgta atgttaagtg aggattttaa
     7561 catagctgac gatttgcaaa aaagtattat attaaatgaa tgtataagta gatttagatt
     7621 tgaaggtgga gaaagagctt ttagatggtt tttaaaggag caaaaagatg aacgctggaa
     7681 agaaataact cttgaagcct gggaaagagg tttttttgaa tttgcaggaa atgcaataag
     7741 tgaacttaag tataagggaa tttctccaga taaacttgaa gaaatattgt caagaggaca
     7801 caaaggaatg cttaaaatta ttttaccaat atataaattg tatgatagaa aattaaagca
     7861 aaatggattg ctagattatg atgatatatt aattttagca gaaaaaactt taagcttaga
     7921 cgaagggctt agaaagaagt ttcaaactag atacaaatat atatttgaag atgagtgtca
     7981 ggactcaaat gaaattcaag gtaatataat aaaaattata tctagcgaaa ataaaaacct
     8041 agttagagtt ggagatataa atcagagtat aacaggaaca ttttcatcat cagaccctaa
     8101 attttttaaa gaatttataa atagtgcaga tttctgttat aggatggata tgtcaaatcg
     8161 aagttcaaaa gatatacttg atttagcaaa cactcttgtc aagtatgtta caaaggaatt
     8221 tagacaagaa gaatgtagac atgctcttga agatatgcaa ataaaaactg tgccaaatgg
     8281 aatgggatat aaagaaaacc ctaatccaga acattataat ataaatgtaa agtggtatga
     8341 gagttggaaa attgaaatag agcaaactgc tagatacgtt aagggtataa aaaataaata
     8401 tccagataaa agtataggta tattggttcc atttaatgaa caagtgacac aagttgctaa
     8461 agaacttaga gagaataatc taacctttga agaattagga ccaaattctt tgaataaaag
     8521 gaaggttata aacaacatag catatattat tgattttatg ttacattgtg atgatgtaga
     8581 aaagttaata gttgtactta ataaagtttt tatagatact gataatgaag aagaaataaa
     8641 gtatttttta gaagaattaa aaaactattc taccgaagaa attatttata attttgaatt
     8701 tagtaagtta gataatgatt taatagaatt taaagaagaa agtgatatat acttaagttt
     8761 taaaagagga atagatatta taaaacagat attagaatat ccaataataa ggttagacct
     8821 cttagttttg tttattggga aaaaacttag tttagaaaaa gaagataaag ctgtactgga
     8881 ttatatatct ttttatataa agtatctagt atcagaaaat ataaatatgg atttagaaga
     8941 tgtatataat ttattgtttg atgtaaagaa cagggtgttt aatcatataa tagatgtggt
     9001 atatgagata aatggatatg aaccagagcc tggtagtata acactatgta actatcataa
     9061 atcaaagggg atggaatggg attgtgtgtt tttactaggt cttgttgaat ataatttccc
     9121 tgacaatatt aatcaaaagt ttcagagtga taaatggtat ctaaaagaaa aatataaaaa
     9181 ccctatggca attattaaat cagaagttga agctatatta aaaggaagta tttcaacaga
     9241 ttatgctcat aaaacgaaga ttgattctat aaatgaaaag attagacttt tatatgtagg
     9301 gattactaga gcaaaggaaa tgttagtact ttcaggaagt gcttatagag atgaaagtga
     9361 tatagggaat aagagaaaag agcaaaaacc atgtatatat ttaagcagac ttaatcaaca
     9421 tattattgaa aaaaggtcaa attaatatat aataagttat taaaagattg tttgaaatat
     9481 atctaaaaga ggataaaaca atatgtacag taagtaacta ctaaaaaata aagttaagag
     9541 agaagtgata tgagtgaacg ataaattaaa atatttttct tatagtcaaa attcaattaa
     9601 cacatataaa tcatgtccat tgaaatttaa atataaatat attgatagaa taaattggaa
     9661 aaatgatgat gttggtagta gagagtatta tgaaacttta aaaacaggaa gagattttca
     9721 tttgatttgt gaaagatatt ttagcaatat acctcttgga atctatttta atgaggatga
     9781 taaaaatagt aaaaagtttt taaagtggat ggaaaatata aaaaaagttg ttcctattga
     9841 aaaaggaaaa acgtatttgc cagaatatga agtaaggatg acattaaatg gggatataat
     9901 acaggcaaag tatgatttag ttgtaattgg aaataacaat atagaaatat gggattggaa
     9961 aaccgagtct aaaaagattg actataaaca cgtagaaaat agaatacaaa ctattgttta
    10021 tatgttttta gcaaaagaag taatacctaa agttttaaaa atggacataa atgttaaaga
    10081 tataaatatg agatattatc aacctgaatt tgatgactta ccaattacca ttttatatga
    10141 tgaagaaaaa catgaagcaa atagaaataa aattcaaaat tatataagta tgataaaaaa
    10201 cactaattat gaagaacata catacgaaga caatctatac aatgatatag aaaaggtata
    10261 taataaagaa gaacgtatgt gctatagaaa taaaaagcat tgcaagtatt gtgaatttaa
    10321 taagttatgt aatggcaaag aaatagatta tagtattttg gaggcggaaa tttatgggac
    10381 ttaggtttgt attaggtaga agtggaagtg gaaaatccac ctatatacta gatgagatta
    10441 aaaaagaagc tcaaaaaaat gaaacgacat caattatact tttagttcca gaacagtaca
    10501 catttgaggc tgaaaataga gtaagtaaac tatttttagg aaaagaaaaa gataagtatc
    10561 taagagttag ggtacttagc tttaagacac taagtaatat agttttttca caagtaggag
    10621 gattgacaga tgtaaatata aattctagtg gaaaagcaat gatggtatat agagctattg
    10681 aagatgtaag tgaagaatta aatgtatttt caaaatcaaa atcgcagtct ggttttgtaa
    10741 gctcaattac agatatgata tcagaaatga aacaatacaa tataagccct gaaatgttag
    10801 aaaatatatc tggagaattg gataatgaaa ctttaagttt aaaattaaaa gatataagta
    10861 aaatatataa ttcttttgaa gggaaattgc atgaaaatta tgtagatgct caagatatgt
    10921 taacttcatt ggcaagtaaa attgaattaa gcagttattt agatggagct tgtgtttata
    10981 tagatgaatt tacaggtttt acaccaaatc agtacaatgt cataaagagt atattaaata
    11041 agtctaaaag tgttaatatc tctttgactg tagatgatat caactatatt gggtacagta
    11101 aatctgatat gttttccaga acgaaattta cttattcaaa attgactcaa ttgtgcaacg
    11161 aagaaggcat aaaaatattg ccacaagtaa atttaaacac aggtgttata aaaagatttg
    11221 aaaaagttaa ggaattacag cacttagaaa gattttataa tgcttatcca tataaaatat
    11281 attcaaatca aactgaaaat ataaagataa aagagtttaa caatttatat tcagaggtgg
    11341 aagagatagc cagagaaatt gtacatttag ttagagataa gaatgtcaga tatagagata
    11401 taaccattgc tacaagagat ttaaatagat atgatttttt agtacactct atatttaatg
    11461 aatataatat accaaacttt atagataaga agagagaggc aaaaagtaat ccaatagtta
    11521 ttttaattat ttcagcttta gaaatgaaga atagacgata tgggtatgaa actatgttta
    11581 ggtatttaaa aagtggactt ataggaattg ataatgatga tataaattta ctagaaaatt
    11641 atgtgttggc taatgggatt aaaggtaaaa aatggtttga tgaaaaatgg gattatagaa
    11701 taacccaaag tctttcaggt caagaaagtg aatttgaact ggaattaaaa gagaaaataa
    11761 atgaaataaa aaatagagta ttagagccta tagtaatttt acaagaaaaa ttaagaggaa
    11821 aaaatagagt aaaagaaatc tgtagatata tatatgaatt tttattagat ataaatatgc
    11881 cagaaactat agaaagttta ataataaatt ttaaggataa aggggaactt gatgttgcaa
    11941 atcaatactc acaagtttgg gacatagtag tggacatatt agaccaaatg gtggaactta
    12001 tgggtgatga aataatttct ttagaaaaat ttataaaatt aataacctta ggttttgatg
    12061 aatatgaatt aggactggtt cctcctagta tagaccaggt acttgtaagt agtgtggata
    12121 gaatgaaaaa tccagacacg aaatatttat acctagttgg aactactgat ggtgtgtttc
    12181 cgctgattac aaaggatagt ggaatattga gtgataatga tagggaaagt cttggaaaca
    12241 aaggaatcga agttgatatt gatagtaaga ctaggagttt tgaagaacag tttcttgtat
    12301 ataaagctct tacttcgaca tctaagaatt taaccataac atatccaata tcagaccatg
    12361 aaggtaaaac gcttagacca tcaataatta tatcaagact taagaagata tttccaaata
    12421 tagaaaataa aagttattta gtggaagaaa ataaaagcac tgataaagat atacttaaaa
    12481 aaataacggt taaatcccct acatttaatg aacttataaa cgtaataaaa aattatgaca
    12541 gtgatggtta caatacagaa gagattaata gtatttggtt agatatatat aggtactatt
    12601 taaaagatga aatctacagt tctataacaa aaaaagttat aaaaggtctt agttatacta
    12661 atcaagttca taagattgaa gagaaaaaaa taaggtcatt gtataaaagt aattctctta
    12721 gcatatctag gcttgaaaaa tatgctgaat gtccatttgc ttattttata caatatggtc
    12781 taaaagcaaa aaagcgtaaa gagtattcat ttacaccacc agatttagga acttttattc
    12841 ataatatttt agataggttt tcaaaagaac ttttacaaga taatttaact tggagagata
    12901 ttgatgaaaa atatatagaa ttaaagatag gtataatagt tgatgaaata attttaaaga
    12961 taccaggata tatattaaat agttctgaga ggtataaata ccttgcatat agattaaaga
    13021 atatgttgac aactgctata actataatta gtcagcaaat aaaacaaggt tcatttgaac
    13081 caatagatta tgaagttaaa tttggcaaca atggaaaata tccacctata aaaatggtgt
    13141 tagaaaatgg acaagaagta agtttaattg gacaaataga tagagttgat gaatttgaag
    13201 aaggagaaaa taaatatata agaataatag attataagtc aggcaataag tccataagtc
    13261 taacagaaat atattatggt ctacaattac aattacttgt gtatttagat gcaatccttg
    13321 aaagtgcaaa ggatgaagat ataaatataa atccagctgc aatactatat tgtagaataa
    13381 ataatccaat agcaaaattt aatgaagata aagatgatga agaaatacaa gaagcaatat
    13441 taaaagaact tagaatgaag gggcttgtag taaaagactc tcacatagtt aaagagatgg
    13501 ataaatcatt aatagatgga gaaaggaaaa actctttagt aataccagta ggtcttacta
    13561 aggatggaaa tgtaggtaaa agtacttcag caataagcta tgaggatttc aaactgctta
    13621 gaaaatatgt aaggcatgct ataaaggatt tatgtgaaga aatgttaagt ggagaaatac
    13681 gtatagctcc atataaacat aaagatggaa catcatgtga cttttgtgat tactctgcta
    13741 tatgtcagtt tgattcaact ataaaagata acaagtataa aaatttaaat aataagagta
    13801 atgaagagat aataaaaatg atgaaaggag atgttaatta gtgagttctc ctaaatggac
    13861 aaaagagcaa ttagaagtta tagaaagtag agaatgcaat ttattggttg ctgctgctgc
    13921 tggttcagga aaaacagccg ttctagttga gcgtataatt caaatgataa caagtagaga
    13981 aaatccaatt gatatagata agttattagt tgttacattt actaatgctg ctgcgtcaga
    14041 aatgagagag aggatagggg atgctatagg aaaagcctta gatgaaaacc cagaaaataa
    14101 acatttacaa aaccaacttg ttttattaaa taaatctagt attacaacaa tacactcatt
    14161 ctgtttggat gttataaaat caaactttca tagaataaac ttagacccta atttcagaat
    14221 aggagaccaa actgaatgtg ctattttgaa acaagaagca atagaggaag tatttgaaga
    14281 tttatatgaa gaaagagatg aggggttttt aaatttagtt gaaagttatg cagaaagagg
    14341 aggagataaa gaagtacaag atattatctt gggaatatat tcatttgcaa tggcttctcc
    14401 tgaacctaaa aaatggttga ttgactcagc agaacgattt aatattgatg aaaattttga
    14461 tttttcacag tctatttggg ctagagctat attagatact gtaaaaatag agattaatgg
    14521 tctttgtcta aatatggaaa gggcattaaa agaagtggaa tcaatagaag aattagaaac
    14581 ttttgcagaa aagttatccg ttgaatataa aaaaattgct gacatttcac aagcatgtaa
    14641 taaatcttgg gatgaggcat ataaaaagat ggcaagtatg tcctttgaaa attatgtaaa
    14701 aggagtaaaa agaatttcaa aagatgctcc ttcgtatata aaagaatcaa aagaaaaggc
    14761 aaaaactata agagataaga ctaagaagtc tttagaaagt atagtaagtg ctacattcaa
    14821 taaagataat gattctatta gagaagaaat aaaatatctt tataacatag ttaaaccaat
    14881 atctagtgtt gtactgagat ttgaagagga atatagcaat aagaaaagag aaaaaggaat
    14941 aatagatttt aacgatatag agcattttgc attaaatata cttacagatg tagatgaaaa
    15001 aggtaatatt gtaccttctg atatagcagt tggatataga aacaagtttt atgaaatatt
    15061 tatagatgaa tatcaggata gtaatctagt gcaggaagta ctgcttaaag ctgttgcaaa
    15121 tacagaaact ccaaatagat ttatggttgg tgatgtaaaa cagagtatat atagatttag
    15181 acaagcaaag ccagaattat ttttgcaaaa atataataac tataatgata aaaagggaag
    15241 ctcccataga aaaataatgc tttacaaaaa ctttagaagt agagaagaag ttgtagatgc
    15301 tgtaaattat atatttgaaa atataatgaa tgagaatata ggagaaattg aatatacaga
    15361 aaaagaaaga ctaaatttag gtgcaaattt taatgtggat acagacgaga aatctattat
    15421 tggtggagca acggagatac acctaataca aaaagataat aaacttgatg atgatattat
    15481 aaatgataaa gacgatagaa ttaataacaa agaaaatgaa atagaggaag aagaaaaatt
    15541 agataatata caacttgagg ctagaatggt tggaaacatt atcaaagatt taatgaaagt
    15601 caatgaagat ggaaaaattc aaaaggtcta tgataaggga atagatggat atagacctgt
    15661 ggaatttaga gatatagtta ttcttttaag agctacatct gcatgggctc cagtgtttgc
    15721 agatgaattg atgaatatgg atataccaac gtatgctgat gttggagtgg ggtattttga
    15781 tacgattgaa ataaaaacaa tattgtcatt acttcaaata atagataatc caatgcaaga
    15841 tatacctctt atatctgtat taaaatcacc tatatttgga tttacaccag aggatttgat
    15901 tgatattaga gttcagagta aagataaaat tttttatgag gttttaaaaa gtacagcaga
    15961 gtatgatgga tttacagatt ctcaaaatga aaatgagtct gagtttatac caagtgaaga
    16021 atgcataaac aaaagtaaag attttttaat taagctaaag gaatttaaag aaaagtcaat
    16081 gtacatgagt acagatgaat ttatatggta cttgtacaca aggactggat actatgccta
    16141 tgttggagca ttgccaggtg gaagtcaaag acaagctaat ttaaaagtat tgtttgagag
    16201 agcaaaacaa tttgaagaaa ccagtcttaa aggaatattc aactttgtaa attttataga
    16261 gaaattaaaa aaatctagtt ctgatatggg aagtgcaaaa acacttggtg agaatgcaaa
    16321 tgttgttaga ataatgagta ttcataaaag taaaggtcta gaatttccag tagtcatatg
    16381 ctctgcaatg ggtaaaaatt tcaatactca agattttaaa aagagtattt tatatcatca
    16441 taatttaggg tatggacctc aatttgtaga ctatgagaga aggatttctt ttccaagtat
    16501 agccaaagaa gcattaaaaa gcaaaataaa tatagaaaat ttatcagaag agatgagagt
    16561 tttatatgtt gcatttacaa gagctaaaga aaaattgatt ataactggtt ctactagaaa
    16621 tatacaagat agtataaaga gatggtcaaa tggaattgaa agtttagata caatatcaca
    16681 atacgagata ttaaaaggta aaaatttttt agattggata atgccttgtg tattaagaca
    16741 tagggattta tctaatctac tagaagaagt aggattagac gcagttttta atgttgaaca
    16801 taattcaaaa tggtatggaa agttgtggaa taagagtgat attttagtgg aaaagaagag
    16861 tgatgaagaa aaagaaagta ttgaagaaat tcttgaaaaa atagatgtag ataatcctga
    16921 tagtgattat tacagtgaaa tagaagaaaa attaaactat atatatccat atgaatttag
    16981 tacaagaaaa cctgctacta tatctgttac agaaataaaa aagatacaaa ataattatga
    17041 agaagagtta ataaatacta tatttgaaca aaaagtaata ttaaaaaagc ctctatttat
    17101 tcaaaatgaa gaagaaagag aaaaaataag tggaacagaa agaggtacaa tagtccattt
    17161 agttatggag gttttagact taaaaaatgt aagtagtgta aatgatataa aatcacaaat
    17221 aagaggtttt gtttcaaaag gtataataac agaaaaacaa gctagtatag taaatccata
    17281 taaaatatat aaattttttg cctctaacat aggaaaaaga atgttgaatg ctgaaattat
    17341 aaatagagaa aaatcaattt atgcacaagt aaatatgaaa gacatatata tttatgaaaa
    17401 gcttataaac aatgacgata aaaaacttta tgataatgaa agtgtcatgt taagaggtat
    17461 agttgatgct tattttgaag aagacaatca aatagttttg gtggattata aaacagattt
    17521 tgtaaatgag gaaaatataa atcaaataat agagaaatat aaaaaacagt tggatttata
    17581 tgcagatatt attgaaactt taactggtaa gtcagtaaaa gagaaatgta tatatttatt
    17641 tggagttgat gaagctgttt gttattagtt tttatatata aattaaacct aaaagataga
    17701 ggaaggggaa aaaatgagat ttattcatac atcagattgg catctaggga agtccctaga
    17761 aggccattct agaattgagg aacaagcaaa gttttgtgag gaatttataa aaatagtaga
    17821 atcaaatgaa atagatatgg ttataattgc tggagatgta tatgatactt ctaatccacc
    17881 agcacaagca gaaaaactat tttatcagac tgtatcaaga cttgccaata atggtcagag
    17941 gtgtgtatta ataatttcag gaaatcatga taatccagag agactctctg caataacacc
    18001 tctagcacat gaacagggga tacttatata tggttatcca ttaagtgcta cgatagaagc
    18061 taagtataaa gggtttgaaa taacatatgc aactcaggga tgtacaaaac tgaatataaa
    18121 tggagaaaat attgtggttg ctacattacc ttatccaagt gaaaaaagat taaatgaagt
    18181 tttttcaagt gaagatgagt ttgagaaaca aaaaaattat tctgaaaagg taggagatat
    18241 atttagaagt ttagaagaaa attttagaag tgatactata aatatagccg tatcacatat
    18301 atttgtaata ggtggagaga gtactgaatc agaaagacct atacaattag gtggaagttt
    18361 tttagttgaa agaaaagatt tgccagaaaa ggctcaatat actgcactag gtcatttaca
    18421 taaacaacaa aaagcttccg aacgtttaaa tgcatactat tctggttctc cacttcaata
    18481 tagcaaggat gaaagagcgt ataccaaagg ggcatacata gtggatataa aagctggtga
    18541 aaaaccaata attgaagatg tatattttaa taattacaaa cctatagaag tatttaaatg
    18601 taatggaata gaagaagcac tagatatatg tgagcaaaat caagatagag agatttggtc
    18661 atattttgaa ataaatactg atgagataat atcacagaat gaaattaaaa aaatgaagga
    18721 actattaaaa gacataatag aaataaaacc aataataaca tcttgttatg aacaagaaag
    18781 tgtagatata aaagaaaagt ctatggcaga gttgtttaga gagttctatt cttttagtaa
    18841 aggtgtagag ccaaaaggag aacttatgga tttatttcta gatataataa gtgaagaagg
    18901 tgaatcagca gatgagacca attagattag aacttacagg gcttaatagc tatattgata
    18961 aacaagttat agactttgaa aaattaattg aaagaggttt gtttgggata tttggaacta
    19021 ctggaagtgg aaaatctaca atcttagatg caataactat tgctatgtat ggaaatatat
    19081 ccagaaatac aaaagaatat ataaacagtg tgtgcgataa ggcaattata tcatacgagt
    19141 ttgagatagg aagcaaaaac actagaagaa gatacattgt agatagaacc attgctagaa
    19201 gcaaaacagg aacaaagacc tctaatgcta gattaataga agtattgaat gacaataccc
    19261 aaaatgtttt agctgataaa gttgtggaag taaatgaaaa agtagcgcag gtcgtaggat
    19321 taacggcaaa tgattttact aggtcagtag ttttaccaca agacaaattt aatgagtttc
    19381 taagattatc acgtgcagat agaagagaca tgttagagag aatttttaat cttgagaaat
    19441 atggaagaag tcttggcgaa aaagtgaaaa agagaaaaaa tatacagtta caaaatttaa
    19501 aagatttgaa atcaaaatta agtcaatatg atggaattac agaggaagta tataacaata
    19561 taaaccaaga attaatagag ttaaaaaatt tggaaaaaga taagaataat gctttagacc
    19621 tagctcaaaa atcttatgaa gaaagtaaaa cagtatatga agaacaatta aagttagaaa
    19681 aaaatgaact tagaaaaaat gagcttgatt taaaaaatag tgagataaaa gaaaagattg
    19741 ctcttgtaga aaatgatagt aacgctaaaa aggtagaccc atacataagt tcagttcaaa
    19801 atctagaaaa aaagatagat gaagatagct tcgcagtaag taatttagaa aagaaattag
    19861 caatattaaa tcaggagctt gaagttacaa aaaatagata tgaaaaaata aacaaaatta
    19921 agaatgaaga aatccctaaa ttgagtgaag aaaaaataag attgcaacaa gcaataaaat
    19981 tagaagaaga gttagtttta ttagatagag agttaaaaga gctaaaagaa agtggaatta
    20041 atttaaataa gactaaagtt gaattagaaa aagtaaagca ggtgtcagag tccagaaaag
    20101 atgcagttac taaatctata aaagaagttg aaggaaagat tgataaagta aatataagtg
    20161 cagaattaaa acaaaaaata tttctagcat atgaatacga gaaagattac aacaacgtat
    20221 tggaagaaaa aaatcaaaag ctaaataaac tagaagaaat actcaaagag acagaaaata
    20281 taaatttaaa agttagatat attgataaag ataagaatga tgtaaatcgt aatttagaaa
    20341 atttatcact tcacttggat gttcttctta aaaaatgtcc tggtaagagt gctgatttac
    20401 ttttaaaatc tgaatatgtt actgaattaa gaaataaagc aaataatact aaagaaaatg
    20461 aaattaagaa aagcagtata caagatgaat taaagataat acttgaaagt aagtttaata
    20521 ctgaaaggga agtaaattta ctaaatgaaa aacttgaaaa taatagaaag aacagagatg
    20581 acttagaaaa agaattagaa gaactaaagt atttaaattt agcctctgaa cttagacgtg
    20641 aattaaaaga aaatatgcct tgtccagttt gtgggtcaaa acatcatgaa aatcatgata
    20701 taactaagta tgatgaaaat atatcttttg tcaaagaaaa actggagaaa ttagaaaaag
    20761 aaaaaataag tataagaaac aatatagagg aattaaatgc taaagtaagt gggtatttat
    20821 ctatagaaaa aatgaagact aaagaacttg aagatgtaaa aggaaaacta ggggggattc
    20881 catctagtca attattaaaa aaacttgatg aagaacaaag aaaacttgca ttgttaaaat
    20941 ctaatattca ggagtgggag aaagaaaaag agagtactga aaataaagta acattagcta
    21001 aagaagaaaa aaataaaatt gaaaaagaag aattaaaaat aagagagagt ctgaataatt
    21061 ataagaaatt aacaagagat ttaaacatag aaatagaagg tttagaaaat aaatgtaaaa
    21121 aacttaaaca ggaataccta ggattaaaga cgattactaa agtctctaat ctattgtcaa
    21181 aagtaaaaga aataagggag aatgaaaaag aattagaatt actaagtact gggcattcaa
    21241 atttattaaa aaatagagac tcactagata ttaaaataag agaaaatgag agtaaactac
    21301 atgaaataga gatagaatta ataaaggcta gagaattata tgtagaaaag aaattgagta
    21361 gagataataa gtataaagaa gttattagca taacgaaagg tgatttagct aaaaatcttt
    21421 tacataatgt tgaagaaaat atatgtaaga tattagaaca agaagaatca agtaagaaaa
    21481 aattggaaga gcaaagatta gaatatgaaa aaaacattgc tgaaaagcac aatatagatg
    21541 gtagacttaa aactgctaag gaacaatata aagaccaaaa atcaacacta aataaactat
    21601 tggcagaaaa taaatttgaa agtatatatg cagtaaaaag agctttatta gatactgatg
    21661 cagtaaaaaa attgattgaa gaaatactag agcatgaaga agaacaaaag ttattatcat
    21721 ttaaaataaa atcatcaaaa gaaaaattaa atggaagaag cataaagaag gagtactttg
    21781 aacagttaaa agatgaaatt tataatttga aagtagaaat aggaaatata tccaaagata
    21841 ttggagctaa tcaaaatcag ttaataacat taaaagactc tttagataag ataaatgatt
    21901 ttaataaaca acttaaggta gttgaacaca atgtggactt attggaagaa ttagataaat
    21961 gtgtacaagg aaataaattt gtagaatatg tttctacaaa ccaattaaaa tatatagcgt
    22021 tggaagcatc aaaacgattg gatggaataa caaaaggaag atatgcactt gaaattgact
    22081 caacactaaa ctttgtaatg agagataact ttaatggagg agaaagaaga agcattgata
    22141 ctctatctgg tggagagaca ttcttgacat ctctatcatt agcacttgct ctttcatctc
    22201 aaatacaatt aaagggaagt gcaccattag aatttttctt tttagatgaa ggttttggtt
    22261 cattagatag tgaactttta gaaattgtta tagaatcctt ggaaagattg catagtaata
    22321 atctaagtgt gggtataata agtcatgtcg aggaacttaa aaatagagtt cctgttaagc
    22381 tattagtttc atctagtgag gctggaatag gttcaaaagt aaaaattgaa tatagttaga
    22441 aaatatatgt taattgaata tattatctaa tatttccaaa taatatgtaa ttgtgatata
    22501 ataaaaacta atattaaagt tatttataat taatattaat ataaaaacat gtaagtagga
    22561 gtgtggtaag tgttggaatc gcccaataat ttgattcaga ttattttttt aatagtatta
    22621 cttatagggt ctgcattttt ctcagcatct gaaacggcct taatgtcgtt gagtaaaatc
    22681 agaatcagat atatgcaaga tgaaggagtt aaaggagcta agttagtaag ttcattaata
    22741 gaaaatccaa ataagctttt aagttctata ttggttggaa ataacgtcgt aaatatagca
    22801 gcaacatcca tatcaacatc tttgtttata ggattaatgg gagaaaaagg agtggcactt
    22861 gctacagctg ttatgacagt attagtatta atatttggtg agattactcc aaaaacaata
    22921 gcagcaaata attcagaaaa ggtttctcta ttagtatcta aacctataaa agcaattata
    22981 tttatattaa gaccaatagt atggatattt aatataatta caaatattat atttaaatta
    23041 tttggtataa caaataaagg agctaaatca ttcataactg aagaagagct aaaaactatg
    23101 gtaaatgtaa gtcatgaaga aggcgtcctt gaaatggaag agagagaaat cataaataat
    23161 gtttttgaat ttggagatat gcaagctaaa aatgcaatgg tacaaagaat agatatggta
    23221 gctatagata tggaagatag ttatgatgag ataatacagg tatttaaaac tgaaaaatta
    23281 agtagaatgc ctgtgtatga agaaactata gatgatattg taggaatact taatataaaa
    23341 gatattatat ttttatctga tgaagaaata gagtcatttg atattaaaaa ttatatgaga
    23401 gaaccttttt tcacgtatga gttcaaaaag ataacacaac ttcttgaaga gatgaaactt
    23461 gaaaaaagtc agatggctat agttgtagat gagtatggtg gaacatctgg acttttaact
    23521 atagaagatt tagtagaagt cattgttgga gatatagagg atgaatatga tgaagaagag
    23581 gatgaaatac aagttataaa agaagatgag tatattgtag atggaagtac taaaattggt
    23641 gatgttaatg aacttattgg tgtaaacttg gaatctgagg agtttgattc cataggaggt
    23701 tttataattg gacacctaag cagattgcca gaagaaaatg aagtaattga agttgataat
    23761 ataagatttt gtatagaaag tatagaaaaa aatagaatta aaaaaataag aatatataca
    23821 taatgtaata atgttcttaa atttattaga agtgtataaa tataaaagat atcttttata
    23881 tttatacact tctttttatt ttgtattcaa ataaaactag tatgaaatgg acaaaataaa
    23941 aatataaatt agaagaaagg agatttttaa gatgagcata ctagaaaata attttttata
    24001 caaattaaaa aacaacacta tctttttttg tatatataca ttgttattta tttttattta
    24061 caaagcgttt ccatacatag ctccattttt tctaggtgct ataatagcac ttatgattaa
    24121 tcctatatca caaaagttag aaaataagtt tcatataaat aaaggtatct ctactcttgt
    24181 tctaagtttt cttgcagtgg ctatagtcag tacagttact acaataatag taataaattc
    24241 aatgaaagaa ttaatgggat ttttaaataa tatatctgct aatcctgagg atataagtaa
    24301 tactattatg tattttttaa ataaaataaa tgactttatg aaatcatttc aagaaatagc
    24361 caattttgat gtagaacaat tagtaaacaa attcagtggt gaagtaatgc aaattacaaa
    24421 aaatcttctt actagtatac ttggattggc tacttctatt ccatatatta taatatttat
    24481 aattaccttg tttattgcta cgtattttat agcaaaagac cttgataaga ttgaaaatag
    24541 tttttataat atgtttactg ttgatgttag aaagaaggta aaaaacgtaa agaaagaggc
    24601 agggctttca cttgttggat atataagggc ctatacaata cttatggcta taacattttt
    24661 tgcaatctgg ggaagttttg ctttatttgg attgaaatac ggtctaatag tagggtttgt
    24721 aggagcttta atggatttaa ttccattcct aggtataata acaatatatc ttccagtaat
    24781 tgtttattat tttcttataa aaaattattt tatagctata agtatgactg tgatattttt
    24841 tgttttgtct ttgattagag aaatacttga acctaaacta gtatcagtaa atgttggact
    24901 aaatccatta gctaccctag cagcgatttt tattggaatc caagtaaaag gaataattgg
    24961 agtaattttt tgtttgggtt tggtatgtat gcatgatata cttaagaagg tggatatttt
    25021 ttaattataa taattgatag attttttaaa aataaaattt tattcacagg taaataaaaa
    25081 aatattaatc ttattaagaa agagggtata tacgtgaaac aaaaagtagt ggaaagattt
    25141 ttaaaatatg tatcatttga tacaacatct aattctcagt gtgagaactg tccatcttca
    25201 gaaggtcaaa gagttttagc taagtatata gttgaagagc taaaaacaat gggtgttgat
    25261 gatgtgagtt tagatgaaaa tagttatata atggctactt taaaaggaaa tactgatggt
    25321 gtggatacta taggattcat atcacattta gatacaattg aagatgttag tggaaaagat
    25381 attaaaccaa aaataataga aaattatgac ggaaaagaca tagttttaaa tgaagcgtta
    25441 aatgttatta cgtatgtaaa ggattctcca gagttggaag aatttaaagg tgacgattta
    25501 atagtcactg atggaacaac tctacttggg tctgatgata aagctggtat agctgagata
    25561 gtgactgcaa tagagtatct aataaatcat ccagaaatta aacatggaga tataaaaata
    25621 ggatttacac cagatgaaga aattggtaga ggtgctgatt tatttgatgt tgaaaaattt
    25681 ggagcaaaat atgcatatac tttagatgga ggaatagttg gagaacttga atgtgaaaat
    25741 tttaatgctg caaatgcaac tattactata catggtagaa atgttcatcc aggttcagct
    25801 aaaaataaaa tggtaaatgc tatacatata gctgctgaaa tatcagaaat gttcccagca
    25861 gatgaaagac cagaaacaac agaaggatat gaaggatttt ggcatttaaa ttctataggt
    25921 ggaaatgtcg agaatgtaag tatggcttat attattagag accattgtaa agaaaaattt
    25981 gaaaatagaa aatctattat gatagagaat atagaaaaaa taaataagaa atacgataat
    26041 agagtggaat tggatttaaa agactcttat tacaatatga aagaaaagat tgagccagtt
    26101 atgtttatag ttgatatagc taaagaagct atggaggaat taggtataaa accacgttta
    26161 gttcctgtaa gaggtggtac tgatggagca agattatctt ttaatggatt accttgtcca
    26221 aatatattta ctggtggatt aaacttccat gggaaaaatg agtgtatacc agttagttct
    26281 atggagaaag ctactaaact aattgtaaga atagctgaaa aatatgctga aagagtttag
    26341 ttaaaaagta tttaaaaatt aagcatttaa agttataata gctatatcat tctttataag
    26401 tcaagctgat tataagcttg tgttgtactt aaaatggtat agctattttt gtaattattt
    26461 ttataaaaga taattatttt tagtttaggg tatcaataaa aagtatgaat atcaataggt
    26521 attaacattt aaaaggggga attgtattga aaattaaatc taaaaaaata atagcatttg
    26581 cactttcact tgggattatg ttgccaagtt gtgtatatgc agacaatatt agtaaaaatc
    26641 aaaatgcaca ggtagatatg aacaattatc ttcaaggtag aaaatctcca aaggaggaaa
    26701 aacttattgg tgaagataga tttgatacag cgataaaaat atctcaaagt ggttggaata
    26761 atggttcaga aagggtgttt ctagttaact caaattcatt gccagatgca ttggcttcaa
    26821 ctcctttggc aagtaaattg gatgcaccaa tactgcttac aaataaaaat agtataccat
    26881 ataatgtaac agaggaaata aaaaggctta atccagcaga agttatttta attggaagtg
    26941 aaggagctat ttcatcaagt gtaaaagaat ctcttgaaga tatggaagta ttagtcagta
    27001 gaatcggtgg agcagataga gaagaaacat ctttacttct tactagacag ctagatgata
    27061 ctggtgattt aggtgtctca aaagtggcag tggttaatgg gtataatgga ctggcagatg
    27121 caacttcaat atcaagccca gctgcaagtg ataatacagc tataatatat acaggtaagg
    27181 atagcataag aagtgaggca aagaatttta ttacacaaaa ctcaactaag acatacatag
    27241 taggtgggga gtacagtata agtaaaaaac ttgaaggaca gttagtaaac tcagaaagac
    27301 tagcagggac agatagaaaa gatactaatg cgaaagtttt agaaaagttt tatggaaaat
    27361 caagtaaggt taataatatg tattttgcaa aagatggaag tggtagagaa gctgatttag
    27421 ttgatgggct tgctgctgga gtattagcat caaaaacaaa gtcacctgta gtacttgcaa
    27481 gtggaagttt aagtagtgca cagaaaagtt ttataaaaaa agtaaaggct gataaatttg
    27541 tacaagttgg tggaggtaaa aatagtaaac catatgcaga agcattagcc ttacagtaat
    27601 attgtgtaaa tcaaaattaa tatataataa tagcaagtaa accaagttgc actttaatat
    27661 atataataaa ataagtaaac taagttatat ttcaatatag catataataa aacaagtaaa
    27721 ccagattcta tttaattaga agtttaaggt attgtactta aacttctaat tgagatagaa
    27781 ataaaatggt ttacttgtct ttattatgaa tttaataaat taaagcttat tttattttta
    27841 ttaaaaattt actaatcatt gatatttatt atatttccag tattgatgtc aattaagttt
    27901 atatcaagtt caagctcatc ctcatcatca gtttttatga tatctataat tgcgacagaa
    27961 tggcttccat cttttgggat agaagtactt cctggattta ttactattaa attatcatcc
    28021 atgtatagtt tttttacatg agtatgtcct aaaactaata tgtcaccacc cattttcttt
    28081 gctttgtcaa taatttcttc ttctgattct atataaccat gattcaatat aattctaatt
    28141 tcaccaaatt ggctcatgac ataaggactc tgaataggat gttctataac catctggtca
    28201 acatctgcat cacagttccc ttttacaatc acaatgtttt ctaatttatt taatgtctca
    28261 ataaattttt taggattata tccttctgga atatcatttc taggtccatg atataagaca
    28321 tctccaccat gtaataaaac atcacaatca gataatacat ttaacgcttt ttcaaagtaa
    28381 agtaagctac catgagtatc actcattatt cctattttca tattaaaaat cctcctaagt
    28441 acagtctata aaaatttttc agatactcta tgccaaaact catagtttga cattctaagt
    28501 aattttattt ttgcatcaga tatactaact tttatatttt cgatttgtct aaatctgtgc
    28561 tcaactccat caacgacaat caatacagaa tcttcaaatc tatattctgg tgcaatcttt
    28621 ataacagatt catttgaaca tattatactt gatgtaaagc acctatatgc attggtattt
    28681 atcggatgta aaggtgtaat ctgcataagt tcaagattta tatcaacaat actacctcca
    28741 gcagaatagt tataggctgt tgaacctgtg gaagtagaaa taatcatacc atctccacta
    28801 aaattttgta tatgtttatt atcaaggctt aaatttaggt gtatagtcct agacttgtct
    28861 cctcttataa caacctcatt tacagcaagc atattagaac cactagtagt tgtatatact
    28921 tccgcattaa gaagtgacat ttcttgaata atataatctt tttttgtata agcttcaata
    28981 aagctatcaa tcttatctgg taaaatatca ggaaaaaacc ccagatgacc tgtatttatt
    29041 cccattatgg gaatctcagg aaaatcgaaa tctctaactg ttcttaaaaa agagccatca
    29101 ccaccaattg atataataag ctctgtgtct ggataaatat ctgaatacac ttcaaagcca
    29161 gcattgataa gttttctagt taagagttct ttagtctcaa gggacttatt taattggttt
    29221 gtatttatag ttataattct tttcatatat tcacctcttc atactttgta ttataacata
    29281 gttttataat tcttaattta taaatttata aatgaccttt gtagtgaatg tgttaaaata
    29341 tgtataggtg ggtataaaaa aatgcataag aggtgaagat gtgtttagca taaggaatat
    29401 cacaaaaaaa ttaggaaaat tcaagttaaa taatataaac ttagagttaa aggaagggga
    29461 tattgttggg attataggac caaatggttc gggaaaaacg actttaataa aaattataat
    29521 ggggattatt gatgcagatg aaggtgaaat tgaactttgt aatgaaacta ttgaaaattc
    29581 tccaataagc tttaaaaaca atattggttt tgtatatgat tctttacaat tttatccgca
    29641 tttaaaggtt aaggaattta gaaaaatagt ttctttattt tataagaatt ttgatagaga
    29701 aaggtttgat gaatacctta ataagtttga tatagaagaa aatatgcata ttgaaaattt
    29761 atctaaaggt caatctgaaa agcttatgtt atcaagtgca cttagtcaca atgctaagtt
    29821 attgattttg gatgaaccaa ctgctgggat agacccaatt gtaagaactg aaataatgca
    29881 gtacttacaa gattttgtga aaaatggaag tagtagtgta ataatttcta ctcataatac
    29941 tgataattta attaaaattg ctgattatct tgtttttata aatagaggaa atcagatttt
    30001 tactgttaag aaagaattaa tagaacaaga atataagata attagggcaa ataaagcaga
    30061 gttagaagca attaaagaaa gcatagttgg tgtgaaagag tataaatatt ataatgaggc
    30121 acttgttaaa gttggagata gcttgaaagt aaaaagccta ttgatagaaa ttgataagca
    30181 taaggtcaaa aatcctacta tagaagaact aatgtattat tatgtaaatg aggtgagatg
    30241 atgttcaatt taataagaaa agatttaata atagggatta gttcagatgg tatccgtaat
    30301 ttaaagtaca tattgctatt ttttgtgttt tattttttcc ttaattcaat ttcatattat
    30361 acagtaagta ttgttgttag ttatttgata tttataaata cgtttgagtg tgattatgaa
    30421 aatgattcaa ggatttttat aaggagtatg ccagttagta tagaagatat agtttactca
    30481 aaatatttat taggtgtagg attaataatt tctgtaacaa taattgtgtc cttactaagt
    30541 aaattgacat cactagtgtt ctttagaaat atggttttaa atgatgtatt tttttctgta
    30601 aatatatttt tagcaatttt gacgatttta ctgcctttaa tttttaagtt tggatatgga
    30661 aaaatgaaag tttgtggttt tatagtaagt attttaattt actttgtata tggaagtctt
    30721 ttgaagatga ttagtatgat tgtatatcaa gtaaagcatt ttaattatag taaagttgga
    30781 ggagtatatc tttcaaatta tgtaactgat atagctaata ctaagtatat aaatttatat
    30841 agtatgacat ttttaacaat aataattttt ataatatcaa tgtatttttc tattaagatt
    30901 tcaaaaaaga ataagtttaa ttattaaaat tttgattaat attatagcac aatagcacaa
    30961 aatataagga gactaaaaat gaagaagttt ataaaagttt cattttttat tttggggatt
    31021 tttacactat tcatagctat aaataaatta gtatatagag atatggtaag tgtcaaagat
    31081 tatgaaataa atcatttaga ggaaattgtt tttgattttg atagcaggag aagtagagat
    31141 gttggtacta ttgtaagatt taaaataagc aataatagta aatatagtta taaattaaac
    31201 agtgctaaaa tgaagtttga aaattgtgtg gaaaataaaa agggaatgaa taagtgttct
    31261 gcatatgtaa atgtagattt atttaatgaa aaaaattcta taactgaaag aactctgaaa
    31321 tatggaataa aaccaaataa tcaaggttat gttgattttg taattccaaa aggactaaat
    31381 tttgattata ggtactttaa tgaatctggt atgagtgtag agtataaagg agaatatatt
    31441 gtcaatattc caatggcaaa aggactttat ctagtagttg gaaaaaataa tgatacatgg
    31501 aatgctaata tcatggaata atttgaaaaa taaatcaatt atagatataa ttaagaataa
    31561 tatgaaattt ataaaagttc agactaggag ggatatttaa tgtcaataag taatgtaaga
    31621 gagtatttta aacaatttgg caaggaagac agtatattag aatttgaaca atctagtgct
    31681 actgtggaac ttgcagctga agcagctggg gttattccag caagaatagc taagacactc
    31741 tcatttaaaa taggagatga tgcaatttta attgtgacag ctggtgatgc taagattgat
    31801 aataagaagt ataaggctga atttaattgt aaggctaaaa tgttgacacc agaagaagtc
    31861 ttggagttta ctggacatgc tattggtgga gtctgtccat ttggtttaaa aaattctata
    31921 aaagtctatt tagatgattc aatgaaaaga tttgatacag tatttcctgc atgtggcagt
    31981 agtaactctg caatagaact tacatgtgaa gaaatggaga agttttctaa gtgtgaaaaa
    32041 tgggtagatg tttgtaagaa ttggtaaaaa aatatagtaa actatagtag gaattagtaa
    32101 aaaactacct ctgtatacaa tctatacaga ggtagttttt ttgtgtaaat atttataaat
    32161 ctaagaggaa aatctaattt aaactaataa tccaaaataa agttaaaaaa ttctgatttt
    32221 ttttcgaaac aataaaaaaa tgacaaaaaa gtggaaaaaa tgtaataaat attgttaaaa
    32281 aaataattag aaattattga aaaattatcc tttgagtgat actattatag atgtaagata
    32341 tttaaaaata aaaaatagtc agataaaaat acgattattt agctctatta aaataatttt
    32401 tatacgataa aaatcttctg tacatggcta aaaaacagat gtacagacaa tatttaatgt
    32461 ttaatatacc ctaatataaa tatcgtaaac aaattatttt atctgtaacc agtgtgaaag
    32521 aaatcttatt ctaacttgaa atttcacaaa attccaaaaa gcgagatttt ttttaagtat
    32581 agttgatttt aaattaacaa tttatgatta aattaatgtc ataattggtt agtataatca
    32641 catataaata tagagcgtag tttgattaag gttataaatt tctcgacgta tattcaaata
    32701 ccttattata gatgttgccg agattttaat taataaatga aaataaaata tttataaaat
    32761 actgaggagg ctattatgga tttaaattct aaaaaatatc agatgcttaa agagctatat
    32821 gtaagcttcg ctgaaaatga agttaaacct ttagcaacag aacttgatga agaagaaaga
    32881 tttccttatg aaacagtgga aaaaatggca aaagcaggaa tgatgggtat accatatcca
    32941 aaagaatatg gtggagaagg tggagacact gtaggatata taatggcagt tgaagaattg
    33001 tctagagttt gtggtactac aggagttata ttatcagctc atacatctct tggctcatgg
    33061 cctatatatc aatatggtaa tgaagaacaa aaacaaaaat tcttaagacc actagcaagt
    33121 ggagaaaaat taggagcatt tggtcttact gagcctaatg ctggtacaga tgcgtctggc
    33181 caacaaacaa ctgctgtttt agacggggat gaatacatac ttaatggctc aaaaatattt
    33241 ataacaaacg caatagctgg tgacatatat gtagtaatgg caatgactga taaatctaag
    33301 gggaacaaag gaatatcagc atttatagtt gaaaaaggaa ctcctgggtt tagctttgga
    33361 gttaaagaaa agaaaatggg tataagaggt tcagctacga gtgaattaat atttgaggat
    33421 tgcagaatac ctaaagaaaa tttacttgga aaagaaggtc aaggatttaa gatagcaatg
    33481 tctactcttg atggtggtag aattggtata gctgcacaag ctttaggttt agcacaaggt
    33541 gctcttgatg aaactgttaa atatgtaaaa gaaagagtac aatttggtag accattatca
    33601 aaattccaaa atacacaatt ccaattagct gatatggaag ttaaggtaca agcggctaga
    33661 caccttgtat atcaagcagc tataaataaa gacttaggaa aaccttatgg agtagaagca
    33721 gcaatggcaa aattatttgc agctgaaaca gctatggaag ttactacaaa agctgtacaa
    33781 cttcatggag gatatggata cactcgtgac tatccagtag aaagaatgat gagagatgct
    33841 aagataactg aaatatatga aggaactagt gaagttcaaa gaatggttat ttcaggaaaa
    33901 ttattaaaat agataaatat taaaatatac acaataggtc gatattaaaa tagatatgga
    33961 ggaaggattt atgaatatag tcgtttgtat aaaacaagtt ccagatacaa cagaagttaa
    34021 actagatcct aatacaggta ctttaattag agatggagta ccaagtataa taaaccctga
    34081 tgataaagca ggtttagaag aagctataaa attaaaagaa gaaatgggtg ctcatgtaac
    34141 tgttataaca atgggacctc ctcaagcaga tatggcttta aaagaagctt tagcaatggg
    34201 tgcagataga ggtatattat taacagatag agcatttgca ggtgctgata cttgggcaac
    34261 ttcatcagca ttagcaggag cattaaaaaa tatagatttt gatattataa tagctggaag
    34321 acaggcgata gatggagata ctgcacaagt tggacctcaa atagctgaac atttaaatct
    34381 tccatcaata acatatgctg aagaaataaa aactgaaggt gaatatgtat tagtaaaaag
    34441 acaatttgaa gattgttgcc atgacttaaa agttaaaatg ccatgcctta taacaactct
    34501 taaagatatg aacacaccaa gatacatgaa agttggaaga atatatgatg ctttcgaaaa
    34561 tgatgtagta gaaacatgga ctgtaaaaga tatagaagtt gacccttcta atttaggtct
    34621 taaaggttct ccaactagtg tatttaaatc atttacaaaa tcagttaaac cagctggtac
    34681 aatatacaat gaagatgcga aaacatcagc tggaattatc atagataaat taaaagagaa
    34741 gtatatcata taatttaagg ggggataaag aatgggtaac gttttagtag taatagaaca
    34801 aagagaaaat gtaattcaaa ctgtttcttt agaattacta ggaaaggcta cagaaatagc
    34861 aaaagattat gatacaaaag tttctgcatt acttttaggt agtaaggtag aaggtttaat
    34921 agatacatta gcacactatg gtgcagatga ggtaatagta gtagatgatg aagctttagc
    34981 agtgtataca actgaaccat atacaaaagc agcttatgaa gcaataaaag cagctgaccc
    35041 tatagttgta ttatttggtg caacttcaat aggtagagat ttagcgccta gagtttctgc
    35101 tagaatacat acaggtctta ctgctgactg tacaggtctt gcagtagctg aagatacaaa
    35161 attattatta atgacaagac ctgcctttgg tggaaatata atggcaacaa tagtttgtaa
    35221 agatttcaga cctcaaatgt ctacagttag accaggggtt atgaagaaaa atgaacctga
    35281 tgaaactaaa gaagctgtaa ttaaccgttt caaggtagaa tttaatgatg ctgataaatt
    35341 agttcaagtt gtacaagtaa taaaagaagc taaaaaacaa gttaaaatag aagatgctaa
    35401 gatattagtt tctgctggac gtggaatggg tggaaaagaa aacttagaca tactttatga
    35461 attagctgaa attataggtg gagaagtttc tggctctcgt gccactatag atgcaggttg
    35521 gttagataaa gcaagacaag ttggtcaaac tggtaaaact gtaagaccag acctttatat
    35581 agcatgtggt atatctggag caatacaaca tatagctggt atggaagatg ctgagtttat
    35641 agttgctata aataaaaatc cagaagctcc aatatttaaa tatgctgatg ttggtatagt
    35701 tggagatgtt cataaagtgc ttccagaact tatcagtcag ttaagtgttg caaaagaaaa
    35761 aggtgaagtt ttagctaact aatttcttgg ggagggtatt atgagtacaa gtgatgttaa
    35821 agtttatgag aatgtagctg ttgaagtaga tggaaatata tgtacagtga aaatgaatag
    35881 acctaaagcc cttaatgcaa taaattcaaa gactttagaa gaactttatg aagtatttgt
    35941 agatattaat aatgatgaaa ctattgatgt tgtaatattg acaggggaag gaaaggcatt
    36001 tgtagctgga gcagatattg catacatgaa agatttagat gctgtagctg ctaaagattt
    36061 tagtatctta ggagcaaaag cttttggaga aatagaaaat agtaaaaaag tagtgatagc
    36121 tgctgtaaac ggatttgctt taggtggagg atgtgaactt gcaatggcat gtgatataag
    36181 aattgcatct gctaaagcta aatttggtca gccagaagta actcttggaa taactccagg
    36241 atatggagga actcaaaggc ttacaagatt ggttggaatg gcaaaagcaa aagaattaat
    36301 ctttacaggt caagttataa aagctgatga agctgaaaaa atagggctag taaatagagt
    36361 cgttgagcca gacattttaa tagaagaagt tgagaaatta gctaagataa tagctaaaaa
    36421 tgctcagctt gcagttagat actctaaaga agcaatacaa cttggtgctc aaactgatat
    36481 aaatactgga atagatatag aatctaattt atttggtctt tgtttttcaa ctaaagacca
    36541 aaaagaagga atgtcagctt tcgttgaaaa gagagaagct aactttataa aagggtaaaa
    36601 atctaattaa aaatatattt gctgttaact agattaaata gtattttaat ctagttaaca
    36661 gaatataaat actaaaataa caggaggtta taactatgaa attagctgta ataggtagtg
    36721 gaactatggg aagtggtatt gtacaaactt ttgcaagttg tggacatgat gtatgtttaa
    36781 agagtagaac tcaaggtgct atagataaat gtttagcttt attagataaa aatttaacta
    36841 agttagttac taagggaaaa atggatgaag ctacaaaagc agaaatatta agtcatgtta
    36901 gttcaactac taactatgaa gatttaaaag atatggattt aataatagaa gcatctgtag
    36961 aagacatgaa tataaagaaa gatgttttca agttactaga tgaattatgt aaagaagata
    37021 ctatcttggc aacaaatact tcatcattat ctataacaga aatagcttct tctactaaga
    37081 gaccagataa agttatagga atgcatttct ttaatccagt tcctatgatg aaattagttg
    37141 aagttataag tggtcagtta acatcaaaag ttacttttga tacagtattt gaattatcta
    37201 agagtatcaa taaagtacca gtagatgtat ctgaatctcc tggatttgta gtaaatagaa
    37261 tacttatacc tatgataaat gaagctgttg gtatatatgc agatggtgtt gcaagtaaag
    37321 aagaaataga tgaagctatg aaattaggag caaaccatcc aatgggacca ctagcattag
    37381 gtgatttaat tggattagat gttgttttag ctataatgaa cgttttatat actgagtttg
    37441 gagatactaa atatagacct catccacttt tagctaaaat ggttagagct aatcaattag
    37501 gaagaaaaac taagatagga ttctatgatt ataataaata agaatttggg aattaaaagt
    37561 ttaaataaaa ttgtttaaaa aacaatttcg gatatatgaa aaatctaatt taatgggggt
    37621 aatgaatatg agagaagtag taattgccag tgcagctaga acagcagtag gaagttttgg
    37681 aggagcattt aaatcagttt cagcggtaga gttaggggta acagcagcta aagaagctat
    37741 aaaaagagct aacataactc cagatatgat agatgaatct cttttagggg gagtacttac
    37801 agcaggtctt ggacaaaata tagcaagaca aatagcatta ggagcaggaa taccagtaga
    37861 aaaaccagct atgactataa atatagtttg tggttctgga ttaagatctg tttcaatggc
    37921 atctcaactt atagcattag gtgatgctga tataatgtta gttggtggag ctgaaaacat
    37981 gagtatgtct ccttatttag taccaagtgc gagatatggt gcaagaatgg gtgatgctgc
    38041 ttttgttgat tcaatgataa aagatggatt atcagacata tttaataact atcacatggg
    38101 tattactgct gaaaacatag cagagcaatg gaatataact agagaagaac aagatgaatt
    38161 agctcttgca agtcaaaata aagctgaaaa agctcaagct gaaggaaaat ttgatgaaga
    38221 aatagttcct gttgttataa aaggaagaaa aggtgacact gtagtagata aagatgaata
    38281 tattaagcct ggcactacaa tggagaaact tgctaagtta agacctgcat ttaaaaaaga
    38341 tggaacagtt actgctggta atgcatcagg aataaatgat ggtgctgcta tgctagtagt
    38401 aatggctaaa gaaaaagctg aagaactagg aatagagcct cttgcaacta tagtttctta
    38461 tggaacagct ggtgttgacc ctaaaataat gggatatgga ccagttccag caactaaaaa
    38521 agctttagaa gctgctaata tgactattga agatatagat ttagttgaag ctaatgaggc
    38581 atttgctgcc caatctgtag ctgtaataag agacttaaat atagatatga acaaagttaa
    38641 tgttaatggt ggagcaatag ctataggaca tccaatagga tgctcaggag caagaatact
    38701 tactacactt ttatatgaaa tgaagagaag agatgctaaa actggtcttg ctacactttg
    38761 tataggtgga ggaatgggaa ctactttaat agttaagaga tagttttaga ttataatatt
    38821 tacaaattaa atatttaatt atgaatttaa cctgtaagaa taactatttg ttattcttac
    38881 aggtttttat agttaaaaat aattattatc tattaaacaa aaatagtgta aaatatataa
    38941 tatcatgatt ttgaagatat aaaaaagtag gaagatataa aagaaagtag gtaaaagttt
    39001 gtttaaaaaa gagaatcaaa gatataatct tatatcgtat acaaatgaag aagaaatgac
    39061 tttaaaagaa gttttattgg acaagctaaa tttctcagtt aggtcattat caaaaatgaa
    39121 gagggaaaag agtgttttag taaatggagt atataaaaaa ccgagtttaa aggtgtatag
    39181 tggtgattta atagaagtaa aaatagacga ggaaaaagca aattttgaac ctcaagattt
    39241 aaatttacag ataatttatg atgattttga tataattatg gtgaataaac ctccgtttat
    39301 ggtagttcac ccaacaaaaa gccactatga taaaacaata gcaaatggta ttagttacta
    39361 tatagataat caaaaagaaa atgtaaaaat aagatttgta aataggttag atatgaatac
    39421 ttcagggtta gttatagtag caaaaaatgc ttatgcacat catactttgt ctacagcaat
    39481 gagtgaaaat aaagttgaaa aaaagtatat aacagtagtt gatggaatta taaaagaaaa
    39541 tgagggaact atagatgagc caatttatag acctacagaa gattcaataa agaggataat
    39601 agatgaaaga ggacagtcat ctgttactca ctataaagta atagaaagac tagaaaatgc
    39661 aactgtatta gaagtaagct tagaaactgg tagaacacat caaataagag tacatatggc
    39721 tcatataggt catggaataa taggtgatga gttgtatggt tatgtagatg aagatctaat
    39781 aaataggcaa gcacttcatg catataagct agagtttgaa caaccaagaa caaaagaaaa
    39841 attgaaattt aaagcagata taccagagga tatgaaagag ttaatatcga aattaagata
    39901 atggggtgat atatatgata atacataaat ttataataca tgttttggac aaaaatagtg
    39961 atgttccaat attaaatgac tttgaaggca aagttaatca agaagtagat ggttttttcc
    40021 agaaagctat aaaaagaatt gcaaaagatg aggatttaag aaaaggtgtt tttaaagatt
    40081 ataatgacaa tttaattaaa aactgttgtg aacaaataat atatgatgaa agtacttttt
    40141 tgaaaaattc taaagaaatt gcatcttact tgtttgatgt tatgaaaatt aatgctgcac
    40201 tagaatcttg tgatttggca atttgcttat acactattaa agatgaaaag agtgtagcaa
    40261 tactgaaatt agattataaa aagttgtaca ctcattcaat tgaatttgtg gatgataaat
    40321 ttaatattca aatggtttca aatgaaattg gtatcccaga gactttaaga caaaagcaag
    40381 gagctttgat tagtctaagt ggtataaatg atgagtttca tctaaggctt ttagataagg
    40441 atgctgaaaa agaagggtca gaatctaagt ttgtaacaga atttttaaat gctaaaaaaa
    40501 tagatgatga taagtacaag accaaggtat ttaaaaatac agctgaaaat tggataacca
    40561 atgctcttag taatgatata aagcaagctg aagatgtaag aagtatatta aattatacac
    40621 tgaaggaaaa acatgaagtt gatataaatg actttgttga taattcaatt aaagatgatg
    40681 agttaaagga tagctttaaa gagcatatgg aagaaaaagg tcttgacgaa agttttagta
    40741 tagataaaaa atgggttgag aaaaagctta aaaaaagaag tataaaaacg gataatggtt
    40801 ttgacataaa agggaatcta actgattttg aagacccaat gaagtatact gtaaaacaaa
    40861 atcaagatgg aactatagat ataataataa agaatgttac gttttatgaa gaaaagtaat
    40921 ttatatactt agtatataaa ttaaatataa gagcgtgtat tttatatatt gtaaataaat
    40981 gtaatctagt ctgtgcgaac tctaatataa tttattatgt agaagtttac acagactatt
    41041 tatatttgta gacaaaacga tactatttgt tttcttcgat atatttacat atatcaccaa
    41101 tacatttaaa gttttcagct tcctcgtctg gtatttctat tccaaattca tcttcaaggg
    41161 ccattataat ttcaacagca tctaatgaat cagcttctaa gtcgtccatt aaagatgctt
    41221 ccatagttat ctcatctaaa ttgtctaccc ctaattgttc tgctattatt tcttttattt
    41281 tctcaaacat tttaagcctc ctaaagcagt tttaattaat tttaatgtta gtttaatata
    41341 atatcaagaa tttttcaata tggaatctat aaaaaataat aaaattttat aaatgtagta
    41401 ataaagtatt atttgatgaa taaactttat tgataacaaa tataacttag gaggaaatgc
    41461 tatgaaatat gtaggactat tactaacttc agtaggaatg tttttactta tagcagtaaa
    41521 tttttattat aattcaataa ctttagatat gcaacgtata gaggattatg taatggagac
    41581 caatttaatc cttgaagatg tagctgaaaa ggagagttat gtatctaatg aaaaagaaga
    41641 ttacatatca aggttaatgc atgtaaagaa aggaatagaa aattcaaaaa catccttctt
    41701 gatagaaaga tataaggagt acaaaataaa atcaatagaa agtttaatct atactatatc
    41761 agaggagaaa aaagattatc tggatgaagt tgatagatac aataaacttg gtgaaaaaga
    41821 aataaataaa ctaatcaata aaaacttttt agaagtaact tatctgtcta ttactacata
    41881 tatttaatta aagagacaaa acttagtctc ttaatgattc aaggaggatt agttatgaca
    41941 aaattagaag acaatatgga acgtttcttt ggaggatgcg aaggattttt tgggaataaa
    42001 atgttgataa taatagttat agtattctta ctattatgca cagacatttt agaagactta
    42061 ttatgcgatg acaatatatg gatatgggtt atattaatag tattgttatt atttaacttc
    42121 gatgatggtt gttgttgcta aaaaatattg attattaaat aggtaaaacc agtaacttat
    42181 acaagttatg gttttacctt ttttagttca aattaaaaaa tttaaaaaaa tagtaaaaat
    42241 acattagcaa aatggaaacc aaatgcatag tatatgttag gagcgaaaag ctcaacaaaa
    42301 tatcaacagg aggtaacgta taatgttaga tagattcttt ggagaagaag gatgttttgg
    42361 tggaggagga tggtggataa tagtactatt cttcctattc ttagcttttg gagatagctg
    42421 ggcagaattt gacataatgg catggatacc attcctaata gttttattaa tactttgctg
    42481 ctgtggtgga tgcttagaat aagaacacag ttattaaaaa aaggagggct ttgttatgtt
    42541 agatagattt tttggagaag aaggatgctt tggtggagga ggatggtgga taatagtact
    42601 attcttccta ttcttagctt ttgaagattg ctggagagac attgacataa tgtcatggat
    42661 acctttctta atattattgc taataacttg ttcatgtggt ggattctttg atggtgaagt
    42721 aggttgcggc tgctaatact taaatcatta gaataaaaaa atgctggtat tttataccag
    42781 cattttttta ttttattttt taatatgatt taaattaaga atgaatatta ttaaatttgt
    42841 tgaatatagg gtataatata aaatataatg tatttaaatg tacttgcttt tatggtaaaa
    42901 taaaaactta tataaatgta gttaaaatag gaaccttcaa aaatttggtt cagttttaga
    42961 taaatttagt aaaataagga ggatgaagat gaaaggcaat ataacgataa aagatgttgc
    43021 taaacaagca ggagtgtcaa tatctactgt atctagagtt ataaatgatt caaaacctgt
    43081 aactgatgaa gtcaaacaaa aagttttaga ggttataaaa gagactggat atataccaaa
    43141 tccacttgct agaagcttag taacaaagaa gagtcaatta ataggggtaa tagttccaga
    43201 agtttcagat tcttttgtta atgaggtgtt aaatgggata gaagaggttg ctaaaatgta
    43261 tgactatgat attcttttag cgaatacata ctctgataag gaacaagaac ttaagagtat
    43321 aaatctattg agagcaaaac aagtggaagg tatagttatg atttcatgga tagttgaaca
    43381 agaacatatc aactatatac aaaattgtgg aataccagcg acatatataa gtaaaactgc
    43441 tagaaattat gatatatata cagtaagtac tagcaacgaa gaagctactt ttgatatgac
    43501 agagcatctt ataaagaaag gtcatgaaaa gatagctttt ataatgacta gtaaagatga
    43561 tactgtttta gaaatggaaa gacttgctgg ttatgagaaa gcactttcaa ataacaatat
    43621 agaattagac aagagtttga ttaagtatgg tggaactgat tatgagagtg gatacaatag
    43681 tatgaaagaa ctattagatg atggaataat acctcatgcg gcttttgtaa caggtgatga
    43741 ggctgccata ggtgctataa atgctatatg tgatgctgga tataaggttc cagaagacat
    43801 atcagttgca ggatttaatg atgttaagat agctagaatg tatagaccta aacttactac
    43861 agtatatcaa cctctatacg atatgggagc agtagcaata agaatggtta taaaattaat
    43921 aaataaggaa ttaattgaaa ataagaaaat agagttacct tatagaattg ttgatagaga
    43981 aagtgttaca gaaagaaaaa aataaaacta ttaaaatcaa tcaggtagtg ccttaggcac
    44041 tacctgattt tttatgtcaa taatatcaaa tttaataata gattaactaa aaataattat
    44101 ctaattgctt aaatagttta tttttatcta ttcatgagga ttagactttt tagttttctt
    44161 aaataaactt ttagattttt tttgttgact acctggtgta ttttttggtg caggtgaatt
    44221 tgacttacct ttagtaggtt tagccttctt agttttagct ggtttagtat ctctttggtt
    44281 ttctgcatct gagatttttt ccattatatt atccagtttt ttgcgttgat tttcatctaa
    44341 aaatgctttg aattttgata ctacttcatc tctgccatct agattcttac ctatttttat
    44401 aagttcctcc ataagttcat tttctgattt tcctttgtaa ctatcagcca tcttttctat
    44461 tttatccttg tcaatatttt tttgtttagc cattttttct aatgactctg tatctaattt
    44521 tttcataaaa aaaccccttt ctataaatat atattgaatt atattcatac tatttatata
    44581 tagaaataat attgaagtgg tgaattgtga gtgatatata atataaataa aaattcttat
    44641 agataatata tatgcactga gctttaaaaa tggaacatta aaatatgaaa aacatacttt
    44701 aatatagggc aattatataa tataaggggg aattgtcttg aataacttac tatttttgat
    44761 tggagtgatt gcattgagta atggtaatat ctctatattt gatgataaaa ataaatcaaa
    44821 aggaaataat agagttagaa aaaacaaaaa aaatgcaaat gataaacttt cacagtctac
    44881 acatggcaat ttaaggtttg atgcaaatga tataaaaaga ggtttaaggc tcatggattt
    44941 aagtgaagaa gatttagaaa tgggaatgga aataataaca agaactaaaa aatacatgtc
    45001 aagagatgaa agaaaaatac taataaaaat agaaagtgtt ttagatttag ttagaggaat
    45061 aaaaaaatta aataatatag atatggtaga tacagaagat gaaacggatt ttttcagaaa
    45121 aatggatagt gatgataaaa agaatatgat gataaaggaa attatagatg tattcccaga
    45181 aaaaagaaaa aattcagttg aaaaagctat aggaatgaaa aagaagatag atttatttgc
    45241 agaattattt ttaccagatg actttggtga aggtggattt agtttgagct ctttggcaaa
    45301 tataaacaat cttggtagta tgaataatct caaattgtta ggaagtcttt taagaggtga
    45361 tgatagtaat aatgatgatg aagacaataa tgatgagtta aattatgaag acgaagaatt
    45421 agattgtgaa gacaaagaat tggatgatga tgagttaaca gatgaaggtg aaatggagga
    45481 taatgaagat gaattagtag aagataagaa cacaggctat gaaaatatag aaaatgatga
    45541 agatatagta tacgatgagg aactatacaa cattaatgag caagaatccg aatacaatta
    45601 taatgaaaaa aatactaaaa ctagagctaa gaaaaaacga taattaacta aatacataaa
    45661 gaaaaaagga agaaaaagta atgatagaat aagattatct caattactat ataaaaccac
    45721 tttaaaaaat tcaaaattta ttatataata ataatatgaa atcctgaaac atacgataag
    45781 gcttttttaa attcaaccta caaatgaaat acgggagacc gtgtctggta aattataaca
    45841 tgcctagtta gtttggacgt taaaggttac tggcaagtca cccacctggg agtgcctagg
    45901 gtgtgaattt acttagccac cggtgtttcg ggacaaaaaa agtgctacta tttcaaatag
    45961 tagtactttt tttattaata tgcatttttc tactaaatac gcctaattat tgataaattc
    46021 aaaaagcaag taacaattaa gattataaaa gcatagtatt aattaggctt caaaaagcca
    46081 aagacttaat aagaatcgct tacagggagg gcaatgaaaa atgcaagatt ataaaaaaaa
    46141 taaaagaaga atgatgaatc agccaatgtc tacaatgaat gaagaagaag tgtatacaga
    46201 tgaaataaat tcagaagaca tgagaggttt taaaaaatca caccatcata atggatgtaa
    46261 tactgataat aagtgtgagt gccatgatga ttgcaatcca tgcaacccat gtaatccatg
    46321 taaacctaac ccatgcaatc catgcaaacc taatccatgt gatgacaatt gtggatgcca
    46381 tgacaattgt aaatgtgatt gtgaaccatg tgaaatggat tcagatgaat gttttgaaaa
    46441 caaatgtgga ccagaatgct gtaatcctat atctccaaga aacttctctg tatcaaatgc
    46501 agtgccattt gcaatagagg ctaatagaat atttgatact atgcaattcc aaacatttac
    46561 agatgcaaca ggaccaaatg gagagccatt aacttttgaa acagaagtag tagaagtatt
    46621 tggttcagtt ccaagtgcag gtcaagcaag tgtaactata gaaaaaatat gcttaagtaa
    46681 tgatggaatc gttatagaca caggaatgac aactttagaa gatttcgatt tagacccatt
    46741 aggagatata gtaggaagaa actgtgaaac aacttttgaa tttgcagttt gtggagaaag
    46801 aaactctgag tgctgtagac aaggaaaagg caaatcagta gcttataaac aaagaggatt
    46861 aactgtagca gttcgtaatt tagtactaga gctaagaggt agatgtggat gtacagagtt
    46921 cgttgcatta gctttcccag cagttagagc aggaggtgga tgtaagagaa gagttgatta
    46981 tgtagaattt acttttaaca cactttcagc accaatatgc ttgccagctg acggaagagc
    47041 tgttacttta agacaagaat atcaaactaa cttaactgta gattgtatag gaaaatctat
    47101 attaaaatta gaatgcaacg aatgttgtga acctttctat gaattaatta taccaaatga
    47161 tatagattta gtactttgct tacaagaaac agttagcaca ttaataagtg aacaaatagt
    47221 agttttagca tcaccaaatc caatccaacc aagacttgtt gatactttct ctaaagtatg
    47281 tgatttttcg caatgtggac ctaatcatgg aagtggaaag ccaagttgcc acagatagat
    47341 aggtagatat atagacagtt taaattataa ataaaaatca tctaaggaag gctaccaaag
    47401 tgtataattt acattggtag ccttcacgtt tttataacta gcgtatagat tttagtgatt
    47461 taaaaagcac tatagtatgt aatagacaag taaagattga tactatcgtc attgtgtata
    47521 tgtatgcata aatattaagt cctggaattg gaagaaatac atataaagct attagttgaa
    47581 ttaacatgcc agtaatagta tttatacttg aagctaattc ttttcttatt gaatgtaaaa
    47641 tgccagatag agtttgattt agggacataa atagtggaac taaaaacata gcttttagat
    47701 attctcctgc aagtgtattt ttaaatacta atatacataa atcttttcca aagaaataaa
    47761 aaaatattga tgatagtatg cctacaaata aagtaagaag tatggagtat ttgatttttt
    47821 taattacact cttacgcttt cttagagcca tttcttgtga aatagttggt attaaattta
    47881 caataagcgc tgaaccaaca gtaaaaggta aaaatataaa aggcattacc atcccactga
    47941 caataccata catacttaaa gattgttgat aagtcattcc tgataatgct aatcttgatg
    48001 gtatcatcat agaacttata gattgcaaaa gtatgtttga cattctatta caagttatgg
    48061 gaatagacat ttttaatgtt tccatagaag aattataaaa atcttttatg cttataatat
    48121 acctattgtc aaatgatgaa tctcgccata agcaaataag cataaatata atattactca
    48181 actcaccaat cgatatacct aatagagcta tataacaatt catagattta ttatttatgt
    48241 acataacaag taaaaaaaca aataatattt taccaatttg ttcaatgatt tgtccaatag
    48301 cagggatttt tacattcttt atgccatagt aatatcctct tagtacgttt gaaagagtta
    48361 ttataactat agcaggacaa acagctagta taaatagatt taatttagca tcttttaaaa
    48421 atttaagtga taaaaaagaa ctattgaaag atgcaactat agatataatt agtgctacga
    48481 aaaatgatat atataaagtt gatataaata aagcattagt attgtgtcta tcgtttaaag
    48541 cttttctctt tgcaactaga caactaagtg cagtaggtat acctgttgtt gtaacagcta
    48601 agcaaatcat caaaaagtta aaaatcatat gatagatacc taaacctgtt tcacctagtg
    48661 ctcttgataa gaatatttta tataaaaaac caaatattct tacaataaaa ttggatataa
    48721 ataaaataac tgttgatagt actaaataag gtactttcaa aaaaatcacc tccttatctt
    48781 ttaaatatat tcacaaggag gtgtaaaaat ttataatttt ataaattctg gtttcaattt
    48841 attaaattta gatacatatt taaatcccat attttttagt aatgaatata tgtagtcaaa
    48901 ctcacatgca acttgactta tatgatgtga atctgaacct gtggttatga tttcccctcc
    48961 caagtctttg tacatttgaa gtatatactt agatggggtt aggtctggaa gattatatct
    49021 ataacaagag gtatttatct cgataccttt gccatcataa atagcttgtt taagagtttc
    49081 ttcaattata tcagaaaata gtctatcatc taaaatagtg tcataaggtg catacctttt
    49141 aatcaaatct aaatgaccta agacagagta atctttataa ttcttaacaa tattatataa
    49201 ataaagatag taattttcat aaacttcatg ttgagtttta tctttaaaat aattaccaag
    49261 gtataagtcc attgtatcta tagcatggat agaacatatt ataaagtcca atggatattg
    49321 atgtgcttcc tttttgtatg tatccattaa ttgagtttga actccaaatt caattccttt
    49381 ttttattgat attttatctt tatatttgct ttgaagagtc tctaaactct taaaataatc
    49441 ttcgtagaca attgaaaaag aatcatcagc atatacatca tagtcaacat ggtctgtgaa
    49501 acaaatttcc tccaaaccga gttcaataga tttttttacc atttcttcca ttgtagattt
    49561 tccgtctgta gagaaacttg agtgcatgtg atagtcgtaa aacataaata tttccccttt
    49621 ttataaaaat tttggtatta tatatacata ctaaataata tcaaatatac ataaaagcat
    49681 caataaaata taaatacaat gagcggtgat aaatttggaa aaatacagaa tagatttaaa
    49741 tgagaaaaaa tcaactaaat atatacagat atttaatcat ataaaagaat tgataataaa
    49801 taaagagtta gtagaacatg aaaaattgcc tccaataaga aaactatcaa attttttaca
    49861 agtaaataac actactatag ttaaggtata cgagctttta gaaaatgaag gatatgtata
    49921 taaaattata gggagtggta cttttgtatc aagtttaaat tcttataaaa gcggtataga
    49981 taacaggaaa aataagatta ttgtgcaaag agaagattta attcattttg acaatgggaa
    50041 tccatctaat gatatgtttc ctatcgattc atttaaaaat gctgtaaata tggcattatc
    50101 taaagatggt agttcaatat ttgaatatga tgaaggtctt ggctctgaag aattaagaga
    50161 aaaaatggta gagtatctaa gtgatggaaa tataaaaact actaaggaaa atattcaaat
    50221 aatatcaggt gctcaacaag gtatagatat agtttgtaaa ggacttataa gttattcaga
    50281 tgttgttttt atggaagaac cttcttacaa tggagcaatt gaagtgttta aaagtagagg
    50341 tgcaaaaata atatctatac ctatgttaga tgatggaatt gatataggta ttttaaaatt
    50401 aaagttggaa aaaataaaac caagacttat atacattatg cctaattttc aaaatccaac
    50461 tggaatatct tactcaacat ataaaaaaaa gaaattgata gaattggcag aagaacatga
    50521 tttttatata atagaagatg attttataag tgattttgtt tttgaatcaa aggacaatag
    50581 aacaattaga agttatgatg ataaaaatag agtagtatat ataaaaagct tttcaaaaat
    50641 acttatgcca ggtcttagga taggaattgt agaaatgcca aatgagttgt taaaaaaagt
    50701 tttatgggct aaatattcat cagatatatc aacaccaggt ttaattcaaa aatcaatgta
    50761 ttactatatg aataattttg attggaagaa ttatttgagt catatagaga agatatatac
    50821 tgataagtat aaattggcaa aaaacttgat taatgacaaa ttgagtggta aattaaaagt
    50881 tagaaaatct tgtggaggaa taaacttttt tttagaatta ccaagaggat atacatctca
    50941 agcatttaca aattttatgt taaacaaagg agtgtcaatg cttccaggga cttatttttt
    51001 tgacaatcta gtggatgata gattctttag gataaatata gctcgtccaa gcatggaaga
    51061 actagaaaag ggaatatcta taataagtga taatatagat gagttttttt gtgaatataa
    51121 aaacaagtta gatataaaaa gcaataaatt attttattaa ataaatagag gttttttagg
    51181 aggaaaaaat gtttgacaag aagaaattag ataggattaa tgaattagca aagaaaaata
    51241 aagagggaat cctttctgct gatgaaatca aagaaagaga aattttaagg aaagaatatt
    51301 tagaaaactt tagagcccac tttagatcaa gactagatag tgtcaaagta gtttcaccag
    51361 aagaatatga gcaatacatg aaaaacaata aaaattagaa cttagtagga ggaaaatatg
    51421 aacttaaagt acgaatttaa gaatgcttgg gattttgaaa gaaaagaaaa tactattgaa
    51481 caaattatgc aatattctag caattatatg gagtttttaa gtaagtcaaa gactgaaaga
    51541 ctttcagtaa aagaaattat aaaattggct aaagaaaata actatatttc aatagatgaa
    51601 gctatggaaa aaggaagcat aagttgtggt gataaaattt atgttataaa taaagagaag
    51661 gcagtagcac tttttgtaat aggtaaaaat tatatagaaa aaggtatgaa gattatagga
    51721 agccatatag attcgccaag attagattta aaaccaaatc cactgtatca agagagtaat
    51781 ctaggttttt ttaagactca ttattatggt ggaataaaaa aataccaatg gacggctatt
    51841 ccacttgctt tacatggtat agttatatta aatgatggaa caaaagtgga catatctatt
    51901 ggggaagaag atagtgaccc agtattttgt gtaactgatt tattgattca tttggctgga
    51961 gaccaaatgc aaaagaaact atcagaagga attagtggag aagctttaaa tatattaatt
    52021 gggaatatgc ctttagaaga tgaagaaaaa gaacctataa cagcaaatat attaaagatt
    52081 ttaaatgaga aatacaatat agttgaagaa gatttattaa gtgctgaaat tgaagtagtt
    52141 ccagctggta aggctagaga tttagggctt gataggtcta tggtgttggg atatgggcat
    52201 gatgataggg tatgttcata tgctgctgta aaagctatac tagaaactga acaaccagaa
    52261 tttacttcag ttgcattatg tgtagataaa gaagaaattg gttctaaagg gaatacaggt
    52321 atgcactcaa agttttttga aaatactgtg gctgaactga ttgctttaga aggagattat
    52381 tgtgatatta aagtaagaag agctttagca aatagtaagg tattatcagc tgatgtttct
    52441 gctggatatg acccaaattt tggagaagca tatgaaaaga gaaattcggc atatatggga
    52501 aatggagtag ttttaactaa gtatacaggt tcaagaggaa agagtggatg taatgatgct
    52561 aatgctgaat ttatgtcaga agtaaagaga atttttaata aaggaaatgt agtatggcaa
    52621 actgctgaac ttggaaaagt agaccaagga ggaggcggaa ctatagccca tatattggca
    52681 aatcaaggtg cagaggttat agactgtggt gttggagttt taaatatgca tgcaccacat
    52741 gagattgtct ctaaagtaga catatatgaa atgtataagg gatataaggc attttttaat
    52801 ataaatttat aagtaaaaat ataaatgtaa taagtgaata aaggctgttg tataaacaat
    52861 ttaatctgtt gtacaacagt cttattttta tgtaaaaata gcaatttgtc acactagaga
    52921 aaataaaaga aaatactgtc aaattaaaaa ttattttaaa aaaaattgac aacgatttca
    52981 tcttgttata atatgtaata aagaacttgt tatataatgt tataaaaatg ttacataggg
    53041 aggtgagcaa aatggatgaa aagagacaaa aaaaagaaat ggatttagaa gtaaattcct
    53101 ttgttccttt atatcaacaa ctatatgaca acataaaaaa acaaatagca tctggcatat
    53161 ataaaccagg agataaactt ccatctgaag gagacttatg taaagaattt aatataagtc
    53221 gtataactgt gagaaatacg acttttttat ataaaatagc aaaataacag tgtttgagca
    53281 aaaaaaaaga atgtttttta tcgttttgcc acctgtttgc caccataact tttttcggtg
    53341 gcaaattatt gtaaaatgcc ctccaaaata tctattgttt cactttccat tttacttgta
    53401 acatgtgaat atgtatccat agtggttgat aattgactat gacctaatct ttgttgtata
    53461 tattttacat tagctccatt ttctaataat aatgtggcat gtgtatgtcg caagcaatga
    53521 aaattaaagt taatatttag tttcttgtta atagttctta tagcagcgtc aatattgttg
    53581 tgatttacaa atgagccatc tttttttcta caaacccaat catactcagt ttctttatac
    53641 cattttccaa ttttaatttt ttgttttttt tgattcaatt tttcctcttt taatattcta
    53701 gacaaagtat cacctatttt aatatctctt attgatgttt ttgtcttagg tgatgctaat
    53761 tcaaattctg aaacttttct ctttattaaa ttttttctaa ctttgattat attattatct
    53821 aaatcaacat tatcccaaca aagacctaat atttctcctt ttctcatgcc tgtatgaaac
    53881 cctataagta gaggaatata gatatttgta tttttaggat atatttctag tattttattg
    53941 aactcatcta gtgttatagt cttgttatct gactcatttt ttacctttaa aacatttttt
    54001 ggtatactgg catattgaac aggattttcc ttaatgagtt tgtaagggta aacagcagat
    54061 tttaaagcag catttaatac aacataaatc gcttttaaaa ctccttttgt gtagtgtttt
    54121 tcttctccgt tttgtgtgta tgtctctttt gatttattat ttaaaaattc ttgaataata
    54181 gctggattta tagattttag cttacattta ccaagtctag gttctatatg attttcaatt
    54241 aaatttctat aactttcctg agtattgtat ttgcaattaa gaagtacata ctctttgtac
    54301 caaaagttaa gatagtctga taaactcata tttgtttcat caaacactat accagcattt
    54361 tcatattcat ttattgcatc acggagcgat ttttcagctt ctttcttagt gtttccacca
    54421 actctttcta ccttttttct cttgccatct actatacctg catcaaagta gtaataccac
    54481 ttctttccac gttttcttac gccgcctttc ataaaatttc tcctctcaaa agcttttttt
    54541 atgtaattat ataataacat atatcaattt aaataaaata aataaaaaag actataagaa
    54601 acaaagtttt atgtttataa ttaatagtct tttttattta gatacatatt taatgttttt
    54661 tatcacgtga ttccagcact ttttctgcca aataaacaac tattttttca tactcaatat
    54721 cagtttctaa agaaaagtca acaatagcag gtatcgtcat atctcctgca tatttattac
    54781 ctaaccaatt ttcaattaat tccaattctt ctttgcttaa ttcaaatttt ttctttttat
    54841 taaaacttaa gttcaattta ttcacctcaa ataatattat atattaaaaa tagtatttga
    54901 tagaaacatt cgaattattt atgtaatttt ctttttttaa tatattcatc agcaaaataa
    54961 tttactaaat atttttcttc caatcctaaa gctatttcta attcaataag aatagggata
    55021 gttaaatctt tatcctcatt attttccaac ctagaaattt gacttctgtg gcaaccaact
    55081 ctttttgcta actctatttg tgttaatttc ttcttttttc gtaactcttt taacatatat
    55141 ttaacctacc ttttagataa ttttatatat gttagtttgt gtaatttctt gtaataaatg
    55201 tgcaatattc gcacactttt tgttggaaat ttgtgctaga atgtagttaa gaaataactt
    55261 tatctagata aagcaaaaat aatagaagct ataaaatata ataatatttt acagttattt
    55321 tatagtttta agctttgaaa aagaggtggt tgtaactatt tttaagaacg tatgtttcgt
    55381 ggaattaata aataaaatat tttatagggg atgatatatt tgaataagac gaaatattat
    55441 gatattttaa agttaaactt attaatgaaa aagttgaaag aattggataa aaataaaatc
    55501 aatgaatata aaataaaagt gaaagaaata cataaaatca ataaaaaaga ggaatgattc
    55561 ctctttttta ttatattcat tttcagaaat aaactatttt ttattttttt cgtctagtaa
    55621 aaataattct gcaactttta atgctttttc tcttgcgtct gggcttagct cgctaaatat
    55681 attaaaaact tctttcatat cttcgtcaag atacatattc tcaataagct ccttttctgt
    55741 tttaaaattt tcagcatcat aatctttttc gtttttattt ataaataagc tatttctaac
    55801 atcagttctt cctaataaat aatctgtaga cacatcaaaa tagtttgcat attcttctat
    55861 tgtacttttc ttaggttctc ttaaaccatt ttctatcctt gatagtgtag atttgtttat
    55921 atgtaaatcc tcgcttaatt tgtctagcga gatgcctttt tcttctctca attcttttat
    55981 cctattcaat ttgcacaacc cctttttata ttaattccaa aatagcaact tttatttata
    56041 ttatagcaac aaaattaatt attacaattt tttttgctaa aaaagcaaca aaagtattga
    56101 ctataatcac aaaacttgat attatataaa tatgaagttg ccaaaatagc aaaaaggaag
    56161 tgatttaatg tacttaaata gattagaagg attgatgaag gaaaatagac acacccaaaa
    56221 aaatgtggca gatatattag gtcttagctc atatggtttt agattaaaat taaaaggaaa
    56281 aaacgaattt aaagcaagtg aaataaaaaa gatatctaaa ttatataatg tatctgcgga
    56341 ttattttttt tcagatgaag ttgctaaaat agcaataaaa gaagaaaggg gcaataataa
    56401 tgaagaatct aaccataatc aagcaaaata atcaattttt agttgaaagt agagaagtag
    56461 cagaattaat agaaaagaag cacgataatt tattaagaga tataagagga tacaagaaga
    56521 ttttagagga ctcatcaaat ttgaggagtc aagatttctt tatagaaagt acttatataa
    56581 atactcaaaa taaaatccaa ccttgctact tattaactaa aaaaggttgc gatatggtag
    56641 ctaataaaat gacaggagaa aaagggatta tatttacagc aatttatgta actaagtttg
    56701 aagaaatgga gcaagagtta aaagaacaac aacctaaatt accaactaca tataaagaag
    56761 cactgcaaca gttattaatc gaagttgaag aaaaagaaca actacaatta gaaaatcaag
    56821 aaaaggataa ggtaatccag ttacaacaac caaaagtact gtttgctgat tcggtagcgt
    56881 cttctgacaa ttcaatccta gttggagaat tagcaaaatt gcttagaca
//
LOCUS       DAMJVG010000016        52905 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.016, whole genome shotgun sequence.
ACCESSION   DAMJVG010000016 DAMJVG010000000
VERSION     DAMJVG010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 52905)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52905)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52905
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.016"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(<1..884)
                     /locus_tag="PC512_001117"
     CDS             complement(<1..884)
                     /locus_tag="PC512_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009243519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HDF2440882.1"
                     /translation="MKLKHIAIIGSLFPILFSLVLFFGVLISADSDDENSNFSSGITG
                     MNLSAEVLKHQTMVEKYARENGISEYVNVLLAIIQVESGGTAEDVMQSSESLGLPPSS
                     LDTESSIKQGCKYFASLLSSCKNQDIDDLNVAIQSYNYGGGYVGYVAGNGKKHTFNLA
                     ESFAREKSGGKKVTYTNPIAVAKNGGWRYGYGNMFYVELVNQYLTVPQVSGELAQKVM
                     NEALKYQGWKYVFGGSSPTTSFDCSGLTQWCYGKAGISLPRTAQAQYDATQHLPLSQA
                     KAGDLVFFHSTYNAGSYVT"
     gene            complement(881..3085)
                     /locus_tag="PC512_001118"
     CDS             complement(881..3085)
                     /locus_tag="PC512_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2440883.1"
                     /translation="MKERIQSAFTKRKILHFLKMALFVVALSLILLSLLGTVAHATGL
                     VDDTINAENLYSKYPLSNYQLDFFVDNSWSWLPWNWLDGIGKSVQYGLYCITNFVWTI
                     SLYLSNATGYVVQEAYKLDFINDMADSIGKSIQTLAGVTENGFSSTGFYVGFLLLIIL
                     VVGMYVAYTGLIKRETSKALHAVINFVVVFVLSASFIAYAPDYIKKINEFSSDISTAS
                     LDLGTKIMLPNSDSEGKDSVDLIRDSLFSIQVQQPWLLLQFGNSNAEEIGTDRVEALV
                     SASPEDEDGKTREEVVKTEIEDNDNNNLTIPQVVNRLGMVFFLLFFNLGITIFVFLLT
                     GMMLFSQILFIIFAMFLPISFLLSMIPSYESMAKQAIVRVFNTIMTRAGITLIVTVAF
                     SISSMFYNISTDYPFFMVAFLQIVCFAGIYMKLGDLMSMFSLNAGDSQSMGRRIFRRP
                     YLFMRHRARRMEHRIARAVSAGGISGGVAGAVAGSAVAGKRAERKNTASKENRGNTTS
                     SMGQRAGSKVGAVLDTKNKVKDKANAVKENIKDMPTQTAYAVYSAKEKAKSSVSDFKR
                     GMVQEQQSRQTGRLEKQEQHKKSIAVKRMELQKAQEARQAQRKADGSATTGATRPHER
                     PATASTVSKTGAEKMQEVKRPATTPTTKASEPVKTSGVKERPLSSSTPDGKATQSTYR
                     QNVEKVTVSKETRQNYTKDRRTKVQQTQTVQKNQQTTEKIRNLVTKKGQKKK"
     gene            complement(3085..5535)
                     /locus_tag="PC512_001119"
     CDS             complement(3085..5535)
                     /locus_tag="PC512_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2440884.1"
                     /translation="MFPIKYIDNNLVWNKDNEVFAYYEMIPYNYSFLSAEQKFIVHDS
                     FRQLIAQSREGKIHALQIATESSIRSMQEQSKKLVTGKLREVAVQKIDEQTEALVSMI
                     GDNQVDYRFFLGFKLMVTEEQLNLKNIKKSAWLTFKEFLHEVNHTLMNDFVSMPNDEI
                     NRYMKMEKLLENKISRRFKVRRLEIHDFGYLMEHLYGRDGIAYEDYEYQLPKKKLKKE
                     TLIKYYDLIRPTRCVIEESQRYLRLEHEDKESYVSYFTVNVIVGELDFPSSEIFYFQQ
                     QQFTFPVDTSMNVEIVENRKALTTVRNKKKELKDLDNHAYQAGSETSSNVVDALDSVD
                     ELETDLDQSKESMYKLSYVIRVSAPDLDELKRRCDEVKDFYDDLNVKLVRPAGDMLGL
                     HSEFLPASKRYINDYVQYVKSDFLAGLGFGATQQLGENTGIYMGYSVDTGRNVYLQPS
                     LASQGVKGTVTNALASAFVGSLGGGKSFCNNLLVYYAVLFGGQALLLDPKSERGNWKE
                     TLPEIAHEINIVNLTSDKDNAGLLDPFVIMKNVKDAESLAIDILTFLTGISSRDGEKF
                     PVLRKAVRSVTQSENRGLLHVIEELRKEDTAISRNIADHIDSFTDYDFAHLLFSDGTV
                     ENAISLDNQLNIIQVADLVLPDKDTTFEEYTTIELLSVSMLIVISTFALDFIHSDRSI
                     FKIVDLDEAWAFLNVAQGETLSNKLVRAGRAMQAGVYFVTQSAYDVSKESLKNNIGLK
                     FAFRSTDINEIKQTLEFFGIDKDDENNQKRLRDLENGQCLLQDLYGRVGVVQIHPVFE
                     ELLHAFDTRPPVQRNEVE"
     gene            complement(5513..5911)
                     /locus_tag="PC512_001120"
     CDS             complement(5513..5911)
                     /locus_tag="PC512_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDF2440885.1"
                     /translation="MKKIKSYTGIWNVEKVLYAINDFNLPFPVTFTQITWFVITEFII
                     ILFGDMPPLSMIEGAFLKYFGIPVALTWFMSQKTFDGKKPYSFLKSQITYALRPKITY
                     AGKAVKLHKQILNETITAVRSVNYVPDKIY"
     gene            complement(6029..6532)
                     /locus_tag="PC512_001121"
     CDS             complement(6029..6532)
                     /locus_tag="PC512_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HDF2440886.1"
                     /translation="MIDDMAVYIANLGRYNEGYLVGAWFTFPIDEEDVKEKIGLNEQY
                     EEYAVHDTDNFPIDIGEYVSIEELNEMYEMIEELPDYIVECLDEFISHYGTLEEVVEH
                     KDDIYFYPDCETMTDVAYYYIDELNALGDIPANLQNYIDYEAYGRDLDMGGRFIETSR
                     GICEIPY"
     gene            complement(6550..7053)
                     /locus_tag="PC512_001122"
     CDS             complement(6550..7053)
                     /locus_tag="PC512_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HDF2440887.1"
                     /translation="MQETRVLVETGRTNGEETTSYWFDLPIDVAEFEEKLGVGAESQD
                     YRIIEKVLPYADEVHEHTSVYQLNELDFMYRQLSADMQEEYVELLTVFENLEALYICR
                     NVITVYHDCKSMIDVARQKLMNDPTFKHLSEDCQAYYFDFEAYASHLLENKRYLVTEN
                     SIFELPE"
     gene            complement(6972..7268)
                     /locus_tag="PC512_001123"
     CDS             complement(6972..7268)
                     /locus_tag="PC512_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005339688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDF2440888.1"
                     /translation="MNDIFKDMQAKVGCEYISDLPSYKRKVWHEMKRLNPADYEEKQL
                     KDFSKYVFGMSYQTLKDVMKQQKGREEQCRKQGYWWKREEQMAKKQHHTGLTYR"
     gene            complement(7367..8140)
                     /locus_tag="PC512_001124"
     CDS             complement(7367..8140)
                     /locus_tag="PC512_001124"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440889.1"
                     /translation="MKGIKVLMISDEMRVDILHAVFINKNFIKDEENCNYEKYLLELV
                     NKSIYFREKSNFAEYVPPKSENHGECDCNSPNYQMDFKLLESTTRLHASKELTGQIQK
                     FCDGVIGKCPPRRPNTQMTVTRLFASLRDYDCESLHSCLTEKYEYGTIEFDIQTYVKL
                     LTFKKNLFFFFPYKFSFNTCYNFKYALDSIRIALEKDFRESNLFREKYYAEYDTFLAY
                     IYEDNLIISKFEQDGKLQMIDCIYLFKSQTYSKLYEYTW"
     gene            complement(8200..8421)
                     /locus_tag="PC512_001125"
     CDS             complement(8200..8421)
                     /locus_tag="PC512_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440890.1"
                     /translation="MNFGQNLYQWFLSNAQSLVLMAIVVIGIYLGFKREFSKLIGFLV
                     VALIAVGLVFNAGGVKDVLLELFNKIIGA"
     gene            complement(8422..8556)
                     /locus_tag="PC512_001126"
     CDS             complement(8422..8556)
                     /locus_tag="PC512_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017143882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HDF2440891.1"
                     /translation="MWELVKDFLLVSMGMGIGVVLMCILSISKEADYEMKQLEESEDN
                     "
     gene            complement(8569..9765)
                     /locus_tag="PC512_001127"
     CDS             complement(8569..9765)
                     /locus_tag="PC512_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HDF2440892.1"
                     /translation="MVLNEEQWIKELREKRIAYGISQGRLAVASGITREYLNKIESGK
                     MKPSKELLETLHKELARFNPEAPLTMLFDYVKIRFPTLDIQHIIKDILKLNINYMLHE
                     DYGHYSYTEHYSLGDIFIYTSADEEKGVLLELKGRGCRQFESYLLAQQRSWYDFLMDA
                     LIDGGIMKRIDLAINDHTGILDIPELAEKCRKREYIGKSRSYKYYQSGELIKHREDDR
                     EYMGSTLYLGSLKSDVYFCIYEKDYEQYVKLGTPLEEADIINRFEIRLRNERAYYAVR
                     DLLTYYDAEQTAFSIINQYVRFIDEEPDKRKNDWKLNDRWAWFIGDNRQSLKLTTKPE
                     PYTLDRTLRWVQRQVAPTLKMLKKIDKGNGTDYMETIEKQAILSEKHEMIIKQQTTPA
                     KDLVES"
     gene            complement(9950..11344)
                     /locus_tag="PC512_001128"
     CDS             complement(9950..11344)
                     /locus_tag="PC512_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008787614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2440893.1"
                     /translation="MRMILNKGHRIRASDKNLVYRFSMGTLLFVFVAVILLLNTKQLM
                     RTDWEHFSLLDNGFTLSLYNFITILIATGVCALVAFLYYRFCYDSFKKLLHRQKLARM
                     ILENKWYEADTVQDSVFFTDLQSRSREKIVWFPKIYYQMEKGLLHIRCEITLGKYQDQ
                     LLRLEDKLESGLYCELTDKTLHDGYIEYTLLYDMIANRITIDEVRAENGCLRLMKNLV
                     WEYDALPHALIAGGTGGGKTYFLLTLIEALLHTNAVLYILDPKNADLADLGTVMGNVY
                     HTKEEMIDCVNAFYEGMVQRSEQMKRHPNYKTGENYAYLGLPPCFLIFDEYVAFFEML
                     GTKESVGLLSQLKKIVMLGRQAGYFLIVACQRPDAKYFSDGIRDNFNLRVGLGRISEL
                     GYGMLFGSDVKKQFFQKRIKGRGYCDVGTSVISEFYTPLVPKGHDFLQTIGFLAQARQ
                     DGTATCEAKGDGSD"
     gene            complement(11438..11875)
                     /locus_tag="PC512_001129"
     CDS             complement(11438..11875)
                     /locus_tag="PC512_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004056026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440894.1"
                     /translation="MCEECYSDENRITPLLNPLDCLENHTQYICGTCGRCICIEHDPN
                     RGLQRWNFPFKSLEIAKLYLRTADYTTKSSCGIYEIENSKGRVSYKIFAGNEDLHLFL
                     KKNKDKKCKQMTPVFNVGEYKEYPHTEVRKLTSDEIKQYMSER"
     gene            complement(11977..12360)
                     /locus_tag="PC512_001130"
     CDS             complement(11977..12360)
                     /locus_tag="PC512_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009588269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HDF2440895.1"
                     /translation="MRLSNGFVIDKEKTFGELKFTAVRDVFLQNEDGTPSTQLKKRIY
                     DLKCSLHGGIIPVSVPPEVPLREFPYNAVVELVNPVADTVSRKTYTGADVDWYVKAED
                     IVLKNKGNQNTGTSQNHTPQGQPKK"
     gene            complement(12376..12702)
                     /locus_tag="PC512_001131"
     CDS             complement(12376..12702)
                     /locus_tag="PC512_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HDF2440896.1"
                     /translation="MEMKYVVPDMAQSFGTLEFAGESEPIFERDKNNRKVIARRSYNL
                     YSDVQKGENVVVEIPVQAGEKHFKYEQKVKLVNPKLYGRGYAIGDVGHTDYVLVADDI
                     VAVEEK"
     gene            complement(12828..15872)
                     /locus_tag="PC512_001132"
     CDS             complement(12828..15872)
                     /locus_tag="PC512_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HDF2440897.1"
                     /translation="MKKILKRLCTGVLAFATVVTALPSTAVHAESKQYWTESEERVGI
                     VEKVMNDGSIGSTFNEGHLTVEGEDAYCIDINTDFKNGYKTRADASTRMSADQISDVA
                     LSLEYVKQYGEAHKELNYKQVYLLEQCVVWQRLSVHLGWQCDNVRASYDEIPKATQDE
                     VFAGAKAFVKENKGRYECGGYIYSGEGQELGQFWAKLNVGNAKLQKTSSNTSITDGNG
                     NYSIAGATYGVFSDKDCTKQLATLTTDKNGNTDVVEVKAGTVYIRELSAPAGYKVDTT
                     VYSLKVEAGKTATLNVSDTPKVTDTLIELFKIDMETQKDNPQGNASLEGAEFTWKYYA
                     GFYNKDNLPAEATRTWVTKTIAETDSDGTTHYITKLADAYKVSGDSFYMQDGKAILPL
                     GTLSVEETKAPNGYLLDGAYMQAGDKSEQIKGLYLTQITEDGDLAVLTGSNQFSVSDK
                     VIRGGVKIQKRDLETSDTKPQGSATLKDTAFDVISLNDNSVLVEGKLYKKNEVVKTIR
                     TDIEGVASTSADLLPYGKFRIVESEAPDGYLTDGAKPIDFAITENGKIVDLTDEAHSI
                     YNQIKRGDIEGVKIGAGTHKRLADVPFRITSKTTGESHVVVTDDNGQFSTSAEWTSHK
                     HNTNAGKTSEDGVWFGTSEADDSKGALPYDTYIIEEMRCDSNKGFELIPPFEIVVSRN
                     NLVIDLGTLTDEYEKEISIHTTATSKDSEKTILAGKEVTIVDTVKLDGLTKGTKYQLK
                     GWQMLKEENAELIIDGKRVENDYTFIADDEEMKVEISYTFNASELGGKNLVTFEELYD
                     LSNPDEPVKVAEHKDIEDDGQTVLITERIIKIHTTATDKDGNKEIEAGKDVTIIDTVT
                     LEGLEVGTQYKLVGWQMLKEENAELLINGKRVESDYTFTADSETMKAEVAFTFDATSL
                     DGKQLVTFEELYDLSNPDEPKKVTEHKDIEDEGQTITFNEKPEVPEKLETPQTPEKPN
                     RPSDSPKTGDSTNVMAFLVMLLTSAGGLAGTYLYKRRTMKKS"
     gene            complement(16115..17479)
                     /gene="rlmD"
                     /locus_tag="PC512_001133"
     CDS             complement(16115..17479)
                     /gene="rlmD"
                     /locus_tag="PC512_001133"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HDF2440898.1"
                     /translation="MLSKNEMYIVDIVDIGQGGVGVGKYNGITVFVEGGLIHDKVKVR
                     INKVKKNYAVGDIVEIIEKSPFRVKRVCSDNLRDCGGCQIQDLDYNKQLEMKTNEVKQ
                     VLSRIGKLEDVEVHDTIGMDNPYRYRNKAQFPIQKNNGIPIIGFYKKKTHDVISTEKC
                     VIQHEINDKIVKIIKTYIRAYKVSIYDEKTHTGLIRHLVTKIGFTTKEVMVVLVANGN
                     KLPYLKELASVLKENIPGFKTLVVNVNQKDTNAILGRENIVIYGDGKINDYIGDLVFE
                     ISPLSFFQVNPVQTKVLYDKALEYANLNDTDTVFDIYCGIGTISLFLAQKAKKVYGIE
                     IIDDAIKDAKINAKLNNIHNAEFYVGKAEEIVPKMYREGKTANVVVVDPPRKGCDEKV
                     LETIVSMNPERIVYVSCNPSTLARDLDYLNVHGFKCVEAQPVDMFPHSTHIETCVLLQ
                     RRTM"
     gene            complement(17654..19414)
                     /gene="pyk"
                     /locus_tag="PC512_001134"
     CDS             complement(17654..19414)
                     /gene="pyk"
                     /locus_tag="PC512_001134"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HDF2440899.1"
                     /translation="MLNNVKKTKIVCTLGPASQSEEVLTQLMQNGLNVCRFNFSHGSH
                     EEHKERIDMAKKVREKLNKPVAILLDTKGPEIRTGNFEDPEVFLEEGQKFTITMKDIM
                     GTKEMCTVSYKGLAEDVKSGDSILIDDGLVGLRVKEINGEDIVCVVENSGIVKNHKGV
                     NVPGVKINLPAITPKDISDIEFGISQGIDYIAASFVRKASDVLAIREVLENNNATDIQ
                     IISKIENQEGVENLDEILKVSDGIMVARGDLGVEIPTEEMPIVQKMMIKKCNELAKPV
                     VTATQMLDSMIRNPRPTRAEVTDVANAIYDGTDAIMLSGETAAGKYPVEAVKMMATIA
                     KRTEETLDYDRLLKENGTNNVTVTDAISHATCTTAVDLNASAIITSTSSGYTARMVSK
                     FRPKSPIIATTNNEKTMNKLALTWGVYPVKSSVAGNTDEVIEKAIEAARQADYIDNGE
                     LVVITAGVPVGVSGTTNLIKVHVISEEIVQGIGVGTQTVEGKVRIIKNGNACVDFNEG
                     DILVSTATDAEMNNYIEKAGAVVTENGGMTSHTAIVGINLDIPVIVSAADITNLVKDG
                     EVVTVDASRGVVYRGSTRVL"
     gene            complement(19466..20425)
                     /gene="pfkA"
                     /locus_tag="PC512_001135"
     CDS             complement(19466..20425)
                     /gene="pfkA"
                     /locus_tag="PC512_001135"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HDF2440900.1"
                     /translation="MKTIGLLTSGGDAPGMNAAIRAVVRSAIYYGCKVYGINRGYKGL
                     LEEDLTEMNLSSVGDIIHRGGTILKSSRCEEFKTEEGRLKAVKILKKYKIDCLVVIGG
                     DGSFAGAQKLSDLGFPAIGIPGTIDNDLAYTDYTIGFDTAMNTIIDAIGKIRDTSSSH
                     ERVNIVEVMGRHCGDLALYAGLAGGAETIIVPEVEITVDEVALRLKTTQKRGKRHSII
                     VLAEGVGSASDLEKELKKESGADLRVTVLGHVQRGGSPTVSDRILASRLGVRAVELLL
                     DGKSARVVGIKENKIIDLEISEALAQKKVFDKEAYEMAKILSI"
     gene            complement(20634..24203)
                     /locus_tag="PC512_001136"
     CDS             complement(20634..24203)
                     /locus_tag="PC512_001136"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HDF2440901.1"
                     /translation="MNKDFAHLHVHTEYSLLDGFSRVKKLIKRAKELNMSSIAITDHG
                     CMFGVIDFYKTAIKEGIKPIIGCEVYTAARGLRDKDPNYDKYQGHLVLLAKNMEGYKN
                     LIKIVSTSYVEGFYYKPRVDMEELKKHNKGIIALSACLAGDVARALMNRNYEKAKQFA
                     LDYRDIFGEENFFLEIQDHNLPEQKEVNSGLVKLSKETGIPLVATNDVHYVNKEDSKI
                     HDVLMCIQMGKTLNDPNRMRFGSDEFYLKSREEMEELFPYALEAIDNTVKIADMCNVE
                     FDFNTIHLPKYDVPEGYTPETYLRELCFNGLKERYDNPSNEILERLNYELDVIEKMGY
                     VEYFLIVWDFINFSKENNIIVGPGRGSAAGSIVAYTLKITDIDPIKYSLLFERFLNPE
                     RISMPDIDIDFCYERREEVIDYVKRKYGDDHVAQIITFGTMGAKAAIRDVGRVLDIGY
                     NKVDKVAKEIPFALGMTIDKALDTNPNLKELYDQDPETKEIINISKQIEGMLRHASTH
                     AAGVVISKNPVDEYVPLYKHQDAITTQFTMTTLEELGLLKMDFLGLRTLTVIRDTLDL
                     IEKNRVIKNYTEKIDFSKMDYDDPKVYEMLSSGNTLGVFQLESAGMRSFMKQLKPDNF
                     EDIVAGISLFRPGPMDSIPAYIKNKSNPKDVTYLHEKLKPIMEVTYGCLVYQEQVMQV
                     VRDLGGYSYGRSDLVRRAMSKKKMDVMEEERQYFIHGKFDEDGNIEIAGCIRNGVEEE
                     IANKIFDDMIDFARYAFNKSHAAAYGVLAYETAYLKTYYPVEFMAALITSVMGNTDKV
                     VEYIRECKALEIDVLPPDINKSFSKFSVEGDNIRFGLAAVKNVGVNIINNIIAERESN
                     GLFVDLVDLVKRLDQKDTNKRVIESLIKCGAFDNISENRASLMAGYESLLESVSMDRK
                     KNVQGQISLFDAFGDSEEDSDFQQIYSLPKRQEYEERERLNLEKEVLGMYVSGHPLSQ
                     FEKELQEKTSMDNGKLNSLKEEEESYLQMNETDVIMGGMIVTKTIKTTKRNEIMAFIE
                     LEDLYGAIEIIVFPQLLQKYNVILNEDNIIYVKGTLSIKEGENAKLIAREIKDINDDT
                     DFADRNYNSGRTRNVENIKPESGKKLYLKIDSMSDTDTTNNIVEIAKQYPGNDSIYLY
                     PMDENINGKRKAYKMTGALTCICDEFINNLEELLPKDNIKVKA"
     gene            complement(24360..25307)
                     /gene="whiA"
                     /locus_tag="PC512_001137"
     CDS             complement(24360..25307)
                     /gene="whiA"
                     /locus_tag="PC512_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HDF2440902.1"
                     /translation="MSFSTETKNELARVISGNECCNIAELSALVKSGGSIQIVGYKKL
                     NLKITTELNSIARKVFKLLKKNFNINTTISVNKNQMLKRNNSYVLMVTSEMGSEMLLK
                     KLGILEDKEGFFTINKISENLIKHEGCKRAFIRGAFLGGGSISDPEKNYHMEFVTNNE
                     EFADSLKELINSLGFNSKIVARKNNHVVYIKESEQISDLLSIIGGHHALLSLQNTKIV
                     KEMRNNVNRIVNCETANLSKTVNAAVRQVENIKLIQETIGISSLPENLQEIAKIRIEY
                     EDMTLKELGEMLEPPIGKSGVNHRLRKIEEIATDLKKKS"
     gene            complement(25324..25749)
                     /locus_tag="PC512_001138"
     CDS             complement(25324..25749)
                     /locus_tag="PC512_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HDF2440903.1"
                     /translation="MREEVSAGGVVLFGNTILLLRKFNGDWVLPKGKVEEGENNQEAA
                     LREVSEETGVKADILKYLGEIHYTFKENWDENRAVHKTVFWYLMQAKNMDTIPQKEEG
                     FIDAKFIHLDRVVDLARYDDEKEIIKVALQEIKKRLKKN"
     gene            complement(25818..26924)
                     /locus_tag="PC512_001139"
     CDS             complement(25818..26924)
                     /locus_tag="PC512_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HDF2440904.1"
                     /translation="MAKLLIIVGILGWIALIVSLFIYKKAKNEKVKLFQRSIVENREP
                     NVVVIGGGTGQSVFLRGLKHTTQNITAIVTVADDGGGSGVLREDLGMLPPGDIRNCLL
                     ALANIEPTMNEVMQYRFTEGLLKGQSFGNLFLAAMNGLYGNFEKAVYKLSEIFAITGR
                     VLPVTLEDVNLVAKLENGNIINGESSIPEESKIQKSSIDKIFLNPKDVKPLKDVIASI
                     YDADIIIMGPGSLYTSIIPNLLVEGIVDAIKSSVAPKVYIANIMTQPGETEGYNVLEH
                     VNAIVKHTDENLIDYVIANNEILPEEMLDLYKQDGAEQVLLDKKQKDKLKEMGIKTVE
                     KNLIEIKNNYIRHDAKYISNIVIELALNHNYNKS"
     gene            complement(26936..27793)
                     /gene="rapZ"
                     /locus_tag="PC512_001140"
     CDS             complement(26936..27793)
                     /gene="rapZ"
                     /locus_tag="PC512_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HDF2440905.1"
                     /translation="MKFVIVTGLSGSGKSETMRALEDMGFYCVDNLPPALITKFAELC
                     YQPNSSIDKVALGIDIRGRKFFEALHESLNYLEKENYEYEMVYLDCNDDVLLKRYKMT
                     RRNHPLAKDMQIPEGIKMERKIMEPLKELSTCIIDTTNMKPKDLKEEIKKIYSSGEDN
                     PNLTISVVSFGFKHGILADADLVFDVRFLPNPYYVEELRAKTGDDKEVRDYVMNSKIS
                     EEFYVKLLDMIHFLVPQYIEEGKQHLVIGVGCTGGRHRSVTITNLIAEDLSNKGYRVV
                     KKHRDSMLR"
     gene            complement(27824..28537)
                     /locus_tag="PC512_001141"
     CDS             complement(27824..28537)
                     /locus_tag="PC512_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HDF2440906.1"
                     /translation="MKILADYHTHTLYSHGKGTIEDNVKVAISKGIKTIGISDHSYKH
                     IAYGVKKKDILKMREEVDYLNDKYTDINILLGMECNILDDKGNIDMDDKFIRDFDYIM
                     AGYHFGSTPTSLRSLLNHCNNYIFKTEKAKEYNTKAVINAISNNDIFIITHPGDKGDV
                     YIEEVAKTAKKTNTRLEINSSHSFLNVNQLNKIKGLENKFIIGSDAHCPERVGDFELA
                     MKTISDSNLDISLVENIII"
     gene            complement(28541..29455)
                     /gene="murB"
                     /locus_tag="PC512_001142"
     CDS             complement(28541..29455)
                     /gene="murB"
                     /locus_tag="PC512_001142"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HDF2440907.1"
                     /translation="MNNQDIYINLLNILSKEDIKVDEPMKKHISFRVGGPADILVRPR
                     TEEQLKNVLKLVKEESIPYLIIGNGSNILIKDGGIRGVVIELADNFNSYEINDTRMTA
                     QSGALLSVLGKALQKQELKGFEFASGIPGTLGGALAMNAGAYGGEMKDIVKSVRLMDM
                     EGNIFELSNEQMEFGYRKSIISKNGYIALSAELELQEGNYDEIKSLMDDLATRRITKQ
                     PLNFASAGSTFKRPTGYFAGKLIEETGLRGLTLRGAQVSEKHCGFVVNQGEASAKDIL
                     DLIYVIKSAVYAKFGVMLEEEVKILGED"
     gene            complement(29728..30498)
                     /locus_tag="PC512_001143"
     CDS             complement(29728..30498)
                     /locus_tag="PC512_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HDF2440908.1"
                     /translation="MSKGFLTPGETAQATISAGIKKANISTQNAILLGLFGGAFIGFG
                     ALGSMIVSQTFGKIDPGVASFLSAMVFPVGLMLVVVAGAELFTGNTLMAIALMDKKIT
                     LGKMLRNWGLVYFANLVGSILLVALVFYSSTLTGDAATKAIAVAEAKVNSTIASMFLK
                     AILCNILVVLAVWMATASQDIMSKLASCWTVIMLFVLCGFQHSVANMFFIPMGMALGA
                     NITMVQFITNLVFVTLGNIVGGSIVVGGIYYLCYVKNS"
     gene            30816..32297
                     /gene="cls"
                     /locus_tag="PC512_001144"
     CDS             30816..32297
                     /gene="cls"
                     /locus_tag="PC512_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HDF2440909.1"
                     /translation="MFDISFFEMSIYEIAVTTIYIINFMVILNLIFREKRNINTTLTW
                     LLILVLIPALGFILYIAFGRNISKNNMFRLKEKDDKIIKSNILDTQVKLQSTSEIDSD
                     IHQHKDMIYALANSNNAHYTNNNDVWIYAESSQFFNSLLEELKKAKKYINIQFYIFKD
                     DKIGTEIIDILIDKAKEGVEVRLLFDAVGGRTLKNSTLSRLKESGVKVGSFFPSFLKI
                     VNFNLNYRNHRKIVVIDGKVGFVGGYNVGDEYLGRNPKFGLWRDTHTKLTGDCVIDLN
                     MRFILDWRYTTKEDLDLEKYFIEEDTNSNHPSENIGIQIVSSGPDISELDEIKYGYLK
                     MIQKARKYIYIQSPYLILDSTFIDTLKIACLSGVDVRVMIPSKPDHPFVYWASYSYAG
                     ELLKFGAKIYTYGQNAFLHAKTIVIDDSICSIGTANMDIRSFELNFEVNAFMYSSKKA
                     LEQRIIFENDILNSKEITLDIYNSRSTYIKIKESISRLLSAVL"
     gene            32615..33112
                     /locus_tag="PC512_001145"
     CDS             32615..33112
                     /locus_tag="PC512_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase subunit E"
                     /protein_id="HDF2440910.1"
                     /translation="MCDFISHNKQLFDELDIFIDSLATKEGALIQVLHEAQGIFGYLP
                     KEVQLHVARKLGVAPAKVYGVVTFYSYFTTEPVGKYKISVCLGTVCFVKGADKILSAF
                     EKQLGIKVGETTSDFKFSLEGLRCLGACGLAPVVTVNGKVYGKVKPDQVSEILDTYRE
                     LELNC"
     gene            33129..35015
                     /locus_tag="PC512_001146"
     CDS             33129..35015
                     /locus_tag="PC512_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoF"
                     /protein_id="HDF2440911.1"
                     /translation="MRKVNSFDELKVLADELKPNLSLRKNYSKENVLRRELLVCCDTG
                     CTSSNSLEIVSELENEIKKSGIQDKVSVRLTGCFGFCAQGPIVKVYPDNVFYVKVEPS
                     DAEKIVQSHLIRNTVVEELLYEEESLSKKVEEQEEMSFYKKQLRIALKNCGLIDPDSI
                     EEYIANDGYLALGKCLTSLTPQEVIAEVKTSGLRGRGGAGFPTGSKWEAASKNPAGPT
                     DKKFVVCNADEGDPGAFMDRSVLEGDPHSVLEAMAICGYAIGSDTGYIYIRAEYPKSI
                     ERLKVAIAQAEKYGLLGENILGTGFNFKLELKYGAGAFVCGEGTALMHSIEGRRGEPR
                     MKTYSSSKSGLWKSPTCLNNVETFANIPAIILKGGDWFANLGTEDSSGTKVFALGGKV
                     ENVGLVEVPMGTTLRDIVFEIGGGIPEGKKFKAVQTGGPSGGCIPTEHLDTPIDFGSL
                     SSIGSMMGSGGMLVLDESDCMVDIAKFFLEFTVEESCGKCTPCRIGTTRLLEILTKIT
                     EGNGTLQDLDDLENLAETIQTASLCGLGKAAPNPVLSTLQYFKDEYIAHVVDKKCPAG
                     KCQNLLSYFITDDCKGCTKCSRVCPAGCITGSVKEQHTIDTSKCLKCGACIDNCTFNA
                     IIKK"
     gene            35038..36819
                     /locus_tag="PC512_001147"
     CDS             35038..36819
                     /locus_tag="PC512_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase small subunit"
                     /protein_id="HDF2440912.1"
                     /translation="MSLVNLTINGKHVSAPSGTSILDAAKLINIKIHNLCHLHMNEID
                     KLDTCASCRVCMVETERGLVPACGTVIKEGMKVQTNSAKALNARRTIVELLLSDHPQD
                     CFVCEKNGDCELQTIAADLGVRKIRYQGSKSFAGKDTSTKSLVKDHSKCILCRRCETV
                     CNDIQTVGALSGVNRGFNTLVSTFFNSDMVETECTFCGQCISVCPTGALTEVDNVPKL
                     WDVLNKKEKTIVVQVAPAVRVAIGEEFGLEPGSISTGKMVAALKALGFEHVFDTNFGA
                     DFTIMEEATEFIERIQKGENLPILTSCCPAWVNFLEHNYPDKLNLASSCKSPQGMFGS
                     IAKNYYAPKILGINPEELYVVSVMPCVAKKYEASREELSESGILDVDLSITTRELAKM
                     IKEAAIDLPNLQDQDFDNPLGKSTGAASIFGASGGVLEAALRTSYEKITNKTLDNVNF
                     TNVRGLKGIREASIDVDGTTVNVCIVNTLKNARKIMDKVRSGECKYHIIEVMACPGGC
                     VGGAGQPYHHGNTEIVDRRANALYEIDRNKAIRKSHENPDLQAIYKDFFGEPNSDVAH
                     KYLHTHYFDKSCVYGECPQECACEEAK"
     gene            complement(36959..38755)
                     /locus_tag="PC512_001148"
     CDS             complement(36959..38755)
                     /locus_tag="PC512_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate oxidoreductase"
                     /protein_id="HDF2440913.1"
                     /translation="MGIEYFSKLLESSTEKELLLSKKSNNISTARLISFLIVIAGFAI
                     GFYNKNIVGIFVGVLSIIIFIALLVIHSKVKEEETYFKSKSEVLNKYIKRFGDGWKEF
                     KIDGKEYLKDENSQAKDLDLFGRASLYQYICVANTSYGKNFLAKYLWNENPDENVILE
                     RQRAIKELLSKDDFSIHIQTLSNIIGKEQKNNSDSSIESFIEYGENKNVYIPKWMHIF
                     TWGLPTATILSFIFCMLGFLPVLPVFLLFIIQLGFSGFGYPRLMQTLAPLFSFSRSIQ
                     VYEKMFEVLEKETFESAYLKELQDKLSKGSGVSRGVKQLNSIGNAVNLRYNQILYIIA
                     CGVLMWNYHCAEALERWKGIYGNQIRDWFESIGEFEALISLTVVSHVKENTCFPVIKY
                     EDTPRLKVEEVYHPLIAEKSVIANSIQLNSQTCIITGSNMSGKTTFLRSIGVNLVLAY
                     AGAPVCAKSFDATCMAIFTSMRIQDDVSQGISTFYAEILRIKSMIQYSLKELPMLVLV
                     DEIFKGTNSADRIIGASEAVKKLSKPWVISMVTTHDFELCDLSGSGDVEVVNYHFSEY
                     YVDDKIHFDYKIKDGRCKTTNAKQLMRMAGIL"
     gene            complement(38969..39898)
                     /locus_tag="PC512_001149"
     CDS             complement(38969..39898)
                     /locus_tag="PC512_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HDF2440914.1"
                     /translation="METSNKVSIREIIKELKLKVVYMPDDVDYYVYSQDINRPGLQFA
                     GYFDYFAYERIQIVGKTEYNFFGLMDSHIREEVLDRFFSYEIPALIISRDLEIKPDVI
                     EKAKKYKRILLSTNRNTTRLINRLSNYLDNKLAPHTTIHGVLVDIYGIGVLIKGESSI
                     GKSETALELIQRGNRLVADDAVEIRKLDESMLVGQSPELIRHFLEIRGIGIIDVRSLY
                     GVGAIKNSKMIDLVVHLEAWDETKYYDRLGLDKEYEEILGVNVEKLVVPVKPGRNTAM
                     ILEVAAMNFRQRGMGYDAAQEFTKKLSKLIDTK"
     gene            complement(39898..41715)
                     /gene="uvrC"
                     /locus_tag="PC512_001150"
     CDS             complement(39898..41715)
                     /gene="uvrC"
                     /locus_tag="PC512_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HDF2440915.1"
                     /translation="MFDIQEHLKKLPSEPGVYLMKDKYDHIIYVGKAISLKNRVRQYF
                     QSSKNHTSKVKSMVKNIYKFEYIITDSELEALILECNLIKRYRPKYNVVLRDDKTYPY
                     IKVTTNEDYPRILKVRRVLKDKAKYFGPYTNITAVNDTLELISSTYPIRSCKIDIDKA
                     IKNKTRPCLNLHINKCLGPCTGNVSKEEYGKMIEEIIMCLSGKEEKLMELLKEKMNES
                     SMNFRFEEAAVYRDKIKSLEEMIQKQKIDATVSDLNQDVVAMARAHNEACVQVFFIRN
                     GKIVGREHFILEGVMDSPRASILSSFVKQFYNEQEYIPKELIIEDEIEDSSILEEWLS
                     SKKGQKVTIRVPQKGEKKSLVEMVRKNAVEYLEKFSDMNKRKYEKSIGALEELKQILN
                     LEKLPIRIEAYDISNIQGVDSIGSMVVYTNAKKDKKEYRRYKIKTVIGPNDYDSMAEI
                     VDRRLKHGNLPDLILLDGGKGQVSAVKKVLELNDVDIPLWGMYKDDKHRTKGLICKEK
                     EIELDKTTNLYRFIASIQEEVHNYAITYHRSLRNKALTKSILDDIQGIGEKRKKSLLN
                     HFKDVDAIKKATMEELLEVDGMNKSIADNVYNFFRKEEN"
     gene            complement(41974..44799)
                     /gene="uvrA"
                     /locus_tag="PC512_001151"
     CDS             complement(41974..44799)
                     /gene="uvrA"
                     /locus_tag="PC512_001151"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HDF2440916.1"
                     /translation="MEDKIIIRGAKEHNLKNIDLELPRDKFIVFTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLGQMEKPNVEYIEGLSPAISIDQKTTSKNPRSTVGTV
                     TEIYDYLRLLFARVGDVYCPTCGEKISQMTIQEIVDKMLDFPDRTKLQILSPIVRGQK
                     GTHKKVFDNIKKEGFVRVRVNGENYEVSDDIILNKNQKHNIEVVVDRIVIKDGIESRL
                     ADSIETAVKLSDGLVIAQIIDGEEILFSTKFACPEHGIGIEELSPRMFSFNAPFGACD
                     VCNGLGESKEVDPELVVPNKDLSIKQGAVAAWGSTGVNDDTYYSKMIKSLAEHFNVSL
                     TTPFKDLPDDFVEELLYGKDNIIVEFTYESKFGGTRNYKSYFEGVIVNLERRYRETNS
                     DYMRDKIEEYMAERPCPKCKGMRLKKEVLSVLVDGKNIMEVTNLSVNELIDFMENINL
                     TEKQRFIAHEIIKEIKGRAMFLRDVGLDYLNLSRKAGTLSGGEAQRIRLATQIGSALV
                     GVLYVLDEPSIGLHQRDNDRLITTLRHLTDLGNTLIVVEHDEDTMREADYVIDIGPGA
                     GIHGGEIVAQGTLDEIIENENSITGQYLSGKKQILLPETTREGNGSFIEIVKASENNL
                     KNIDVKFPLGKFTCITGVSGSGKSTLINDILYKGVASKVNRLKQRAGKHKEIKGIESI
                     DKVINIDQSPIGRTPRSNPATYTGVFDFIRDIFASTNEAKARGYKKGRFSFNVKGGRC
                     EACKGDGIIKIEMHFLPDVYVPCEICKGERYNRETLQVKYKDKTISDILDMNVEEAVE
                     FFENIPNIKRKLETLMDVGLSYIKLGQPSTQLSGGEAQRIKLAAELSKRPTGKTLYIL
                     DEPTTGLHMADVDKLIQVLQRLADTGNTIIVIEHNLDVIKTCDYVIDLGPEGGDKGGT
                     IVATGTPKEVSKVDGSYTGQFLKKYFS"
     gene            complement(44818..46788)
                     /gene="uvrB"
                     /locus_tag="PC512_001152"
     CDS             complement(44818..46788)
                     /gene="uvrB"
                     /locus_tag="PC512_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HDF2440917.1"
                     /translation="MDFKIKSDFKPTGDQPEAIKSIVDSINRNEKFSTLLGVTGSGKT
                     FTMANIIQQVKKPTLIMAHNKTLAAQLYSEFKEFFPDNAVEYFVSYYDYYQPEAYVAH
                     SDTYIEKDASINDEIDKLRHSATASILERRDTIIISSVSCIYGLGDPKDYKELMLSIR
                     PGMQRDRDDVIKRLIEIQYERNDINFTRGTFRVRGDILEIFPASNDEKAIRIEFFGDE
                     VDRITEIDYVTGKIVGTRNHVVIFPASHYVTTPERIEKAIVEIENELQEQIKFFKEND
                     RLLEAQRIEQRTKYDIEMLKEIGFCQGIENYSRHITGRSEGERPYTLMDFFPDDYLII
                     VDEAHVTIPQVRGMYAGDRSRKTSLIENGFRLPSALDNRPLNFQEFEGNINQMLFVSA
                     TPGPYEIQHSETIAEQIIRPTGLLDPIVEVRPINNQIDDLVGEITKTIEKNERVLITT
                     LTKKMSEDLTNYLKEIGIKVKYLHSDIVTLERTEIIRDLRLGKFDVLVGINLLREGLD
                     IPEVSLIAILDADKEGFLRSETALIQTIGRAARNENGRVIMYADRITDSMQNAIDETK
                     RRRDIQNLYNEEHNIIPKTIQKNIRDSIEATKVAEEEVVYGISDTDDKDEIRANIDKL
                     KSEMMEAAQNLQFERAAELRDKVKQLEEKLEK"
     gene            complement(46975..48237)
                     /locus_tag="PC512_001153"
     CDS             complement(46975..48237)
                     /locus_tag="PC512_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HDF2440918.1"
                     /translation="MTKVIVLSVDSLFEKDLEFVKNLPNFKSILENCSIVKNINCVYP
                     TLTYPCHTSMVTGVYPKKHGIYHNEKFDPNKENKDWYWYSKDIKAKTIIDVAKENNLT
                     TSSVLWPVMGANPNIDYNIAEIWAPSREDDPRETFERSSSKVIMDGIYNRHCHYIDWK
                     LEPNMDLFGVNCSVDIIKEYKPDLMLIHLATLDHTRHNYGLFNDEVDKALKMNDKWLG
                     DIIQATKDAGTYKDTNFIILGDHGHLRVDKVINPNVLLKSNGFIKVENGEVKDFDAYV
                     NSSGISAQIIVNNLDRLTELRELLEEFKEELFIENIFTKEEASNLGLEGDFEMVIEGL
                     EGISFGNDFEGSIIKDSDIKDYKFAVATHGHLPTKGNRPPFIAFGPNIKGGVVIEEGD
                     LRAHAATILKMFNLKLDGVEKEAFDFIM"
     gene            complement(48300..49604)
                     /locus_tag="PC512_001154"
     CDS             complement(48300..49604)
                     /locus_tag="PC512_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2440919.1"
                     /translation="MKLKRKLATGLAITLLLGSLVGCSNSNDANASKGEKTDSNITKI
                     DFWAPLGGTNGETAQKMVDQFNSEHKDVQVNMLKQKDYYENATKLQAALTSKDQPDVT
                     LLEITQTGTFASAGALVDMSKYFDKTYQERFFSGLLTNSYYEDKFVGMPFNRSTPILY
                     INKDMATKAGLDPSGPKSWEELKDYASKMTNKSEDTYGFETPIDIWFYEAMVMQSGGE
                     ITNGKKVAFNNEAGQAPVKFWQDMMKAGIMKMPPGEDYNAWDVAKQDFVNGKVGMIFT
                     STADLAGLMQQTEGKFEISTAFLPKNQKYATPTGGANLVMLEGGTDKEKEASAEFIEW
                     MTQTDKIVQFSSSTGYLPTTEDATNSEKLQTLYKEKPQYKVATDQLQYAVALPMLNGY
                     KEATDKLMDEIKKGLTDLNANPKDVVSKGTSAMQAVIDKTNK"
     gene            complement(49635..50495)
                     /locus_tag="PC512_001155"
     CDS             complement(49635..50495)
                     /locus_tag="PC512_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDF2440920.1"
                     /translation="MDIIQPIKKDKVDIKKIASKSIEILILLLLSAIFIFPFIWMLST
                     SFKNPQEMMQLPPTIIPNDIVLENYSTAWHSGPFFRYLLNSVFVTGSVLIVQFLVMVP
                     AAYAFSKIKFKGEKMLFGLLLVGLMIPPQVTFLPVYMMMSKFGFINTYVPLIIPFMTS
                     SFGIFLLRQNFMQISDEIIEAAKLDNASDLKIMFRIMVPMAKPAVITFILFNFIYHWN
                     NYFWPLVMTNTDAIRTLPIGVALLKSSEGITAWNVIMAGNIILILPIILVYIFANKKV
                     KEAFMYSGIK"
     gene            complement(50539..51408)
                     /locus_tag="PC512_001156"
     CDS             complement(50539..51408)
                     /locus_tag="PC512_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDF2440921.1"
                     /translation="MKKQFNKAYLYITPAIIGTLLFIVYPIIKTISLSFKSGSLLSST
                     FENVGLNNYTELLKNPEFIQTITNTAIYTFFMVTISISLAIVLAVWLNKNSIIHNLTQ
                     SIIFTPHVISLVSVAVLWLWIMEPQYGFLNWILSTLHLPTSKWLSSESSALMSLILIG
                     IWKTLGYNILIVLSGLKSIPNYIYEASKLDNANKITNFFKVTLPLLSPTIFFLMITTT
                     TASFQVFDEISIMTQGGPVGSTNMLSYYIYESGFIYYDIGQASAASMFLLAIVMIATY
                     ANFRLLSKKVHYQ"
     gene            complement(51392..52462)
                     /locus_tag="PC512_001157"
     CDS             complement(51392..52462)
                     /locus_tag="PC512_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2440922.1"
                     /translation="MADIRLENVTKSYNKKNTVIENLNLTIEDGSFTVLVGPSGCGKS
                     TTLRMIAGLEDITSGRLKIEENDVTKTDASKRDIAMVFQNYALYPHMTVRENIEFGLK
                     NKKVEKEKREKLITEVIDVVGLREYLNVKPGNLSGGQRQRVALARAMVKNPKVFLMDE
                     PLSNLDAKLRNQMRTELIQLHQKLKSTFVYVTHDQVEAMSMADKIVIMNKGKIMQIGS
                     PKKIYQNPKNLFVAQFIGSPCMNILDIKNDIKFGFRPEKATLESINIDGKNDDVFSLF
                     GKVVTKEVLGNETIYCLSVLNREIRVKTENDIFDIGRTLRISVLEKDLYYFDKNGERI
                     EDVKVCKSMYSKIKGDIYEKAI"
BASE COUNT        15508 a        10358 c         7532 g        19507 t
ORIGIN      
        1 gttacatacg aaccagcgtt ataggtggaa tggaaaaata ccaaatcgcc agcctttgcc
       61 tgcgagagtg gaagatgttg ggtagcgtca tactgggctt gtgccgttct cggtaaggag
      121 ataccagctt ttccatagca ccattgcgtc agtcccgaac agtcaaagga agtggttgga
      181 gaagaaccac caaacacata tttccaccct tgatatttca acgcttcatt cattaccttt
      241 tgtgccagct ctcccgatac ctgcggaaca gttaaatact gattgactaa ttccacatag
      301 aacatatttc catagccata ccgccagcct ccgttcttcg caacggctat cgggttggta
      361 taggttactt tctttccacc cgatttctca cgggcgaagc tctctgcaag attaaaagtg
      421 tgtttctttc cgtttcctgc cacatagccc acatagccac cgccatagtt ataggactgt
      481 atcgctacat tcaaatcgtc gatatcttga tttttgcagg aagaaagcag ggacgcaaaa
      541 tacttacacc cctgcttgat tgagctttcc gtatctaagg aactaggcgg taaaccaaga
      601 ctttctgaac tctgcataac atcttctgcc gtaccgccac tttctacttg aatgatagcc
      661 agtagtacat tgacgtactc ggagataccg ttttctctgg cgtatttttc taccatagtc
      721 tgatgtttca aaacttctgc ggataagttc atacccgtaa tgccagaaga aaagttgctg
      781 ttttcgtcgt cgctgtccgc actaatcagc accccaaaga aaagcaccag agaaaagaga
      841 ataggaaaca gacttccaat gatagcgata tgtttcagtt tcattttttc ttctgtcctt
      901 tcttcgttac aagattacgg attttctctg tggtctgctg gttcttctgg acagtctggg
      961 tctgctgaac ctttgtccta cggtctttgg tgtaattctg gcgtgtttcc tttgacacgg
     1021 taactttttc tacattctgc ctatatgtcg attgggtcgc tttcccgtca ggagtactag
     1081 aagatagcgg acgttctttg acaccgcttg tcttaactgg ttcgcttgct ttcgtagtcg
     1141 gagttgtggc agggcgtttg acttcctgca ttttttccgc acccgtcttt gaaacggttg
     1201 aagctgtggc tggtcgctca tggggacggg tagctcccgt tgtcgctgat ccgtcagcct
     1261 ttcgctgtgc ctgccttgct tcttgtgcct tttgaagctc catacgcttg acagcgatac
     1321 ttttcttatg ctgttcctgc ttttccaagc gtcccgtctg tctggactgc tgttcctgca
     1381 ccataccacg cttgaaatca gacacgctgg actttgcctt ttcctttgcg gaatacaccg
     1441 cataagcggt ctgtgtgggc atatccttga tattctcttt gacagcgttt gccttgtctt
     1501 tcactttatt tttcgtatct aagacagcac ccacctttga gcctgcacgc tgtcccatac
     1561 tggaagtggt attgccccga ttttctttag aagccgtatt ttttctttcg gctctcttgc
     1621 cagcaacggc acttccagct accgcaccag ccacaccgcc cgaaataccg ccagcactta
     1681 cagcccttgc aatacggtgt tccatacgcc tagcccgatg tcgcatgaac agatacggtc
     1741 tgcggaatat cctgcgtccc atgctttgac tgtcgccagc gttgagagaa aacatactca
     1801 ttaagtcgcc cagcttcata tagataccag cgaaacatac tatctgcaag aacgccacca
     1861 tgaaaaacgg atagtccgtg gatatgttat aaaacatact ggaaatgcta aacgcaaccg
     1921 ttacaatgag cgttattcct gcccgtgtca ttatggtatt aaataccctc acgattgcct
     1981 gctttgccat gctttcatag ctcggtatca tggaaagtag aaagctgata ggtaaaaaca
     2041 tagcgaagat aataaaaagt atctggctga acaacatcat acccgtaagc aagaatacaa
     2101 atatcgtaat accaagatta aagaacaaga ggaagaacac catacctaaa cggtttacca
     2161 cctgcggtat cgtcagattg ttgttgtcgt tgtcctcgat ttctgttttc acgacttctt
     2221 ctctggtctt tccgtcctcg tcctctggac ttgccgatac gagagcttcg acacggtctg
     2281 tcccgatttc ctctgcgttg ctgtttccaa actgtaagag tagccacggc tgttgtactt
     2341 gaatagaaaa taggctgtcc cgtatcaagt ctacgctgtc cttgccctcg ctgtcagagt
     2401 tggggagcat gatttttgtt cccaaatcaa gcgaagcggt actgatgtct gatgaaaatt
     2461 catttatctt cttgatgtag tcgggagcgt aggcaataaa cgaagcggac agcacgaaca
     2521 ccaccacaaa gttgataaca gcgtgaagtg ccttgctggt ttcccgtttt atcagtcccg
     2581 tataggcaac atacattccc accactaaga taataagaag caggaaacca acatagaagc
     2641 ccgtagaaga aaagccgttc tcggtaacgc ctgcaagggt ctgtatgctt tttccgatac
     2701 tgtctgccat atcgttaata aaatcaagtt tataggcttc ctgcaccaca tagccagttg
     2761 cattgcttaa ataaaggctt atcgtccaga caaagttggt aatgcagtaa agcccgtact
     2821 gtaccgattt tccgataccg tccagccagt tccacggaag ccacgaccag ctattatcga
     2881 cgaaaaaatc aagctggtag ttggaaagcg gatattttga atatagattt tctgcgttta
     2941 tggtatcgtc cacaagcccc gtcgcatgag ccaccgtccc cagaagtgaa agcaggataa
     3001 gggaaagtgc caccacgaac agagccattt tgagaaagtg aagtatcttc ctttttgtga
     3061 acgcactctg tatcctttct ttcatcactc cacctcattt ctctgtacgg gcggtctagt
     3121 atcaaaggcg tgtagtaatt cttcaaagac tgggtgtatc tgcaccacac cgacacgccc
     3181 gtataagtcc tgcaataaac attgtccgtt ctccaaatca cgcaagcgtt tctggttgtt
     3241 ttcgtcgtcc ttgtcgatac cgaaaaattc taaggtctgc tttatctcgt tgatgtcagt
     3301 agaacgaaat gcaaacttca aaccgatatt gtttttcaga ctttcctttg acacgtcata
     3361 ggcagactgg gtaacgaaat aaacgcctgc ctgcatagct cgtccagcac gaaccagctt
     3421 atttgatagg gtttcgcctt gtgccacatt taagaacgcc cacgcttcgt ccaaatctac
     3481 aatcttaaaa atgcttctgt ccgaatggat aaaatcaagg gcaaaggtac taatcacaat
     3541 cagcatagac accgacaata attcaatggt cgtgtattcc tcaaaagtgg tatctttatc
     3601 tggcagtaca aggtctgcta cttgaatgat attgagctgg ttatcaaggc ttatagcatt
     3661 ttctaccgtc ccgtctgaaa acagcaggtg tgcaaagtcg tagtccgtga agctgtcgat
     3721 atggtctgcg atattgcgtg agatagcggt atcttctttt ctcaattcct caataacgtg
     3781 taacagtcct ctattttcac tctgggtaac agaacgcacc gcttttcgta acacggggaa
     3841 tttttcgccg tccctagagg aaatacccgt aaggaatgtt aagatgtcga ttgccagact
     3901 ttcagcgtct ttcacattct tcataatcac aaatgggtca agaagtcctg cattgtcctt
     3961 gtcgctggta aggtttacga tattgatttc atgggctatc tctgggagcg tttctttcca
     4021 gttgccacgc tcacttttag ggtctaacag aagtgcttga ccgccaaaca gcaccgcata
     4081 atatacaagt agattgttgc agaatgactt tccaccgcca agacttccca caaaagcaga
     4141 agcaagggca ttagtaactg tgccttttac tccctgcgaa gctaaagacg gttgcaggta
     4201 cacatttctt cccgtatcaa cggaatagcc catatagata cccgtgtttt cccctaactg
     4261 ctgggtcgca ccaaaaccaa gcccagccaa gaagtctgac tttacatact gcacatagtc
     4321 attgatatat cgcttgctgg caggtaaaaa ttcagaatga agtcccaaca tatcgccagc
     4381 aggacgcacc agttttacat tgaggtcgtc gtaaaagtcc ttgacttcat cacaacggcg
     4441 tttcagctcg tcaagatcgg gtgcagacac ccgtatgacg tagcttaact tatacatact
     4501 ttctttgctc tggtctaaat cggtttccag ctcgtccacg ctgtctaaag cgtccaccac
     4561 atttgagctg gtttcacttc ctgcttgata ggcgtgatta tccaaatctt tcaattcctt
     4621 tttcttgttg cggactgtcg ttaatgcctt acggttctcc acgatttcta cattcataga
     4681 agtatcaacg gggaatgtga attgctgttg ctggaaatag aagatttcag aggacggaaa
     4741 atccaactcc ccgacaatta cattgacggt aaaataggac acatagcttt ccttgtcctc
     4801 atgttccaat cgtaaatacc gctggctttc ctcaatcaca caccttgtcg gacggataag
     4861 gtcgtagtat tttatcagcg tttctttctt caatttcttc tttggtagct ggtactcata
     4921 atcttcatag gcgataccgt ccctgccgta aagatgttcc atgagatacc caaaatcatg
     4981 gatttccaag cgacgcacct taaagcgacg ggagatttta ttttccagta acttttccat
     5041 tttcatgtaa cggttgattt catcattcgg catggaaaca aaatcattca tcagcgtgtg
     5101 gttcacttca tgaagaaatt ccttgaacgt cagccatgcc gattttttga tgttcttcag
     5161 attgagctgt tcttccgtaa ccatgagctt aaagccaaga aaaaagcggt agtccacttg
     5221 attgtcccca atcattgata ctaacgcttc ggtctgttcg tctatttttt ggactgccac
     5281 ctcacgaagt ttgcctgtta ccagtttctt tgactgctcc tgcatacttc taatggagct
     5341 ttctgtggca atctgcaacg catgaatttt tccctcacgg gactgtgcga ttagctgtcg
     5401 aaaactgtca tgcacgataa atttctgctc tgcggataga aaagaatagt tgtacggtat
     5461 catctcatag taggcgaaca cctcattgtc cttgttccag acaaggttat tgtcaatata
     5521 ttttatcggg aacatagttc acactcctta ctgccgtgat tgtttcattc aatatctgct
     5581 tatgcagttt tacggctttt cctgcataag tgattttagg tcgcaaggca taggttatct
     5641 gtgatttcaa aaagctgtac ggcttctttc cgtcaaaggt tttctgcgac ataaaccaag
     5701 tgagagcaac gggaataccg aagtatttga gaaatgctcc ctcaatcatg gaaagtgggg
     5761 gcatatcccc aaacagaatg atgataaatt ccgtaatcac aaaccatgta atctgtgtaa
     5821 aggtaacggg aaagggtaag ttaaagtcat tgattgcata taagactttt tccacgttcc
     5881 agatacccgt gtagctttta atctttttca agttctttca gcccctttcg taagttcttc
     5941 aaagagaaaa ggacagccat tttcagactg tcccttaaag agaaatacgc tgtcagtagc
     6001 aacaatgctt gttgctgatc ttccagcgtt aatatggtat ctcacagata cctcggcttg
     6061 tttcaatgaa tcgaccaccc atatccaaat ctcgcccgta ggcttcatag tcaatatagt
     6121 tctgtaagtt agctggaatg tccccaagtg cgttcaattc gtctatgtag tagtaggcaa
     6181 catctgtcat ggtttcacaa tcgggataaa aataaatatc gtccttatgt tccacgactt
     6241 cttccagcgt cccatagtgg ctgataaatt cgtccagaca ctctacgata tagtcgggaa
     6301 gttcctctat catttcatac atttcattga gttcttcaat ggaaacatat tcccctatgt
     6361 cgataggaaa gttgtcggta tcatggacag cgtattcttc gtactgttca ttcaagccga
     6421 ttttttcttt tacatcttcc tcgtcaatag ggaaagtgaa ccacgcaccg actaaatatc
     6481 cctcattgta tctgccaaga ttagcaatat aaaccgccat atcatcaatc ataagcacca
     6541 cctcatttcc tattctggca gttcaaagat actgttttcc gttacaagat agcgtttgtt
     6601 ttcaagtaag tgagaagcgt aggcttcaaa atcgaaatag tatgcttgac agtcctcgga
     6661 taaatgtttg aatgtcgggt cgttcatcag cttttgcctt gcaacatcta tcatgctttt
     6721 acagtcgtga taaacggtaa tcacgttcct gcaaatataa agtgcttcta agttctcaaa
     6781 cacggtaaga agttctacat attcttcctg catatcggct gatagctggc ggtacataaa
     6841 atctaattcg ttaagctggt acacgctggt gtgttcgtgg acttcatcag cataaggcaa
     6901 caccttttcg ataatgcggt aatcttgact ttctgcaccg acacctaact tttcttcaaa
     6961 ctctgcaaca tctatcggta agtcaaacca gtatgatgtt gtttcttcgc catttgttct
     7021 tcccgtttcc accagtaccc ttgtttcctg cattgttcct cacgtccttt ctgttgtttc
     7081 atcacatctt ttaaggtctg gtatgacata ccaaacacat atttagaaaa atctttcaac
     7141 tgtttttctt catagtcggc agggttcagc cgtttcattt catgccacac cttacgcttg
     7201 taagagggca ggtcggaaat gtattcacag ccgacttttg cctgcatatc tttaaaaata
     7261 tcgttcattt catcactcca atctgaaatt taggtaagaa aaaagcagtc aatcctaaga
     7321 ctaactgctt tgtgtgtaag tatgaatttg tttaagtgta actgatttac catgtgtact
     7381 cgtaaagttt actgtatgtt tgacttttaa ataaatatat acaatcaatc atttgtaact
     7441 tgccgtcttg ttcaaattta cttattatca gattatcttc atagatatat gctaagaaag
     7501 tatcatactc tgcatagtat ttttctctaa aaagatttga ctctctaaaa tctttttcta
     7561 aagcaattct tatactgtct aaagcatatt taaagttata acaagtatta aaactaaact
     7621 tgtatggaaa aaagaaaaat aagtttttct tgaaagtaag caatttcaca taggtttgta
     7681 tatcaaattc aatcgttcca tactcatatt tctctgtaag acaagaatgt aaactttcac
     7741 aatcataatc ccgcaacgaa gcaaataacc tagttacagt catttgtgta tttggtcttc
     7801 tcggtggaca cttaccaatt acaccatcac agaatttctg tatttgacca gtaagttctt
     7861 ttgaagcatg aagtcttgtt gtgctttcaa gtaatttaaa gtccatttga taattaggtg
     7921 agttacaatc acattctcca tgattttcag atttaggtgg tacatattct gcaaaatttg
     7981 atttttctct aaaatatatt gatttattaa ctaattccaa caagtatttt tcataattac
     8041 aattttcttc atctttaata aaatttttgt ttatgaatac tgcatgtaaa atatccactc
     8101 tcatttcatc tgaaatcata agcactttta ttcctttcaa aaaataattt atcgtaccca
     8161 cattataaca ttctcatatt acagcaacaa taaaattcgt tatgctccaa taatcttatt
     8221 gaacagctct aacagtacat ctttcacacc gccagcgttg aatactaagc cgacagcaat
     8281 aagggcaact accaagaagc caataagttt tgaaaactca cgcttgaacc ctaagtagat
     8341 accgataacc acaatcgcca taagcactaa gctctgtgca tttgataaaa accattgata
     8401 caaattttgt ccgaaattca tttaattgtc ctcgctttct tctaattgtt tcatttcata
     8461 gtcagcttct ttgctgatac tcaaaataca catcaagact acgccgatac ccattcccat
     8521 agataccagc aggaagtctt ttactaattc ccacattttt tatcactcct aactttccac
     8581 caaatctttt gcaggggtcg tctgctgttt gattatcatt tcatgctttt cactcaagat
     8641 tgcctgcttt tcaatcgttt ccatgtagtc tgtaccgttt cccttatcaa tctttttcag
     8701 cattttcaag gtcggtgcta cctgtctttg tacccaacgc aatgtgcggt ctaaggtgta
     8761 aggttctggt tttgtcgtca gtttcagact ttgccgatta tcgccaataa accaagccca
     8821 gcggtcattg agtttccagt catttttccg cttgtctggt tcttcatcaa taaaccgcac
     8881 atactggttg atgatagaaa aagcggtctg ctctgcgtca tagtaggtca gcaaatctcg
     8941 tactgcatag taagcacgtt catttctaag ccgtatctca aaacggttga taatgtcggc
     9001 ttcttccaga ggtgtaccta atttgacata ctgctcatag tccttttcat agatacagaa
     9061 atacacatct gatttcagcg aaccaagata aagggtactc cccatatatt ctctgtcgtc
     9121 ctctctgtgc ttgataagct cgcccgactg gtaatactta tagcttctgg actttccgat
     9181 atattcccgt ttcctgcatt tctccgcaag ctctggaata tccaaaatgc ccgtatggtc
     9241 gttgatagca aggtcgatac gcttcataat gcctccgtct atgagtgcgt ccataagaaa
     9301 gtcataccag cttctttgct gtgccagcag gtaactttca aactgcctgc aaccccgacc
     9361 ctttaactct aaaaggacac ctttttcttc gtcagccgac gtatagataa agatgtcccc
     9421 taatgaataa tgctccgtat aactgtaatg tccgtaatct tcatggagca tataattgat
     9481 attcagtttt aatatgtctt tgatgatgtg ctgtatatcc agcgtgggaa aacgaatttt
     9541 cacataatca aacagcatgg taagcggtgc ttctggattg aaccttgcca gttctttatg
     9601 caaagtttcc agaagttctt ttgacggctt catttttccg ctttctatct tgtttagata
     9661 ttcccttgtg ataccagaag ctaccgccag cctgccttgt gagataccgt aagcaatccg
     9721 cttctcccgt aattctttta tccattgttc ttcattcaga accatacccc caatctgtca
     9781 agtgtgaagt tttttaaggc gacttcacag ccgatttttg ctaggaaacc atgccagaag
     9841 ccttatgttt cctatgtttt tttgtctatt gtctatttgc aaacgtaccc ctctgttaga
     9901 taccgagggg ttttacctgc tggcgtggct tacgccacac cagcaacggc tagtccgagc
     9961 cgtcgccttt cgcttcgcac gtcgccgtcc cgtcctgcct tgcttgtgca agaaaaccga
    10021 ttgtctgcaa aaaatcatgt cctttcggga ctaaaggcgt gtaaaattca cttatgacgc
    10081 ttgttcccac atcacaatag ccacgccctt tgatacgctt ttggaaaaac tgctttttca
    10141 catctgaacc aaacagcata ccgtaaccta actcgctgat acgccccaat cccacacgta
    10201 aattgaagtt atctctgata ccgtccgaga aatattttgc gtctggacgc tggcaggcaa
    10261 cgataaggaa ataacctgct tgtcgtccta acatgacgat tttctttaac tggctaagta
    10321 agcccacact ttcttttgtc cccagcattt caaaaaacgc cacatattca tcaaagataa
    10381 gaaagcaggg tggcagtccc agataggcgt aattttcgcc cgtcttatag ttcgggtgtc
    10441 gtttcatttg ctcgcttcgc tgtaccatgc cctcataaaa agcattgaca cagtctatca
    10501 tttcttcttt ggtgtgatac acgtttccca tgactgttcc caagtctgct aagtccgcat
    10561 ttttcgggtc taagatgtaa aggacagcgt tggtatgcag tagggcttca atgagcgtca
    10621 gaagaaaata tgttttaccg ccaccagtcc caccagcaat cagagcgtga gggagtgcgt
    10681 catattccca gacaagattt ttcatcagtc taagacagcc gttctctgcc cgtacttcat
    10741 caatggtaat gcggttcgct atcatatcat aaagcagggt atattcgata tagccgtcat
    10801 gcagggtctt gtcggtcagc tcacaataca agccactttc caatttatcc tctaaccgta
    10861 aaagctggtc ttgatatttc cccagcgtaa tttcacagcg gatatgaagc agtccctttt
    10921 ccatttgata ataaatcttt ggaaaccaga cgattttttc ccttgatctg ctttgcaggt
    10981 cagtaaaaaa aacgctgtct tgtacggtat cagcttcata ccacttgttt tccagtatca
    11041 ttcgtgccag cttttgacgg tgcagtagct ttttgaaact gtcgtaacag aagcggtaat
    11101 acagaaaagc gaccaatgca caaacaccag tcgctatcag tatggttatg aagttgtaaa
    11161 gggaaagcgt aaagccattg tctaataagc tgaaatgttc ccagtcggta cgcatgagct
    11221 gttttgtatt taatagcagg ataaccgcta cgaacacaaa caggagtgtc cccattgaaa
    11281 agcgatagac aaggttctta tcgctggctc tgatacggtg tcctttgttt aaaatcattc
    11341 tcataaatca atcactcctt tctgggtatg aaaaaagcag tcaatcgtat agactaactg
    11401 ctttgtgtgc atggatatga agttgtcaaa ctggaattta acgttcactc atatattgtt
    11461 ttatttcatc agaagtcaat tttcgtactt ctgtatgtgg atattcttta tactctccaa
    11521 cattaaacac aggtgtcatt tgtttgcatt tcttgtcttt attctttttc aagaatagat
    11581 gtaaatcctc attcccggcg aatattttat aagatactct gcctttactg ttctctatct
    11641 cataaatacc acatgaactt ttcgttgtat aatcggctgt tcgtaaataa agttttgcaa
    11701 tttccaatga cttaaaagga aaattccatc tttgtaatcc tctgtttggg tcatgttcaa
    11761 tacaaatgca acgtccacaa gttccacaaa tatattgagt gtggttttct aagcagtcca
    11821 agggatttag taatggtgtt attctatttt catcagagta acattcttca cacatttttc
    11881 ttttcgctcc ttatcaaatt ctaatttgtc gctttcttca tacccatatt ataacagttc
    11941 cgtatatcct ctacaacgaa aatctattca gcaagtctat tttttcggtt gtccctgcgg
    12001 tgtatggttc tgtgaagtgc ctgtgttctg attgccttta ttcttcagta caatatcttc
    12061 tgcctttaca taccagtcca catctgcacc cgtataggtt tttcgtgata ccgtatcggc
    12121 tacgggattg acaagctcca cgactgcatt gtaaggaaat tcccttaacg gtacttctgg
    12181 cggtacggac acggggataa ttccaccatg cagactgcac ttcaaatcat agatacgctt
    12241 tttaagctgg gtactcggtg tcccgtcctc attttgcaag aacacatcac gcaccgctgt
    12301 aaattttaat tctccaaatg ttttctcttt gtcaatgaca aatccatttg ataatctcat
    12361 aaattcttca ctcctttact tttcttcaac tgctacaata tcatcagcta ctaatacata
    12421 atcggtatgt cccacatccc cgattgcgta ccctctgccg tataacttcg gattgacaag
    12481 ttttactttc tgttcatact tgaaatgctt ttcgccagcc tgcacgggaa tttccaccac
    12541 aacattttcg cctttctgta cgtcagaata aaggttatag cttcgtctgg ctatgacctt
    12601 gcggttgttt ttatcccttt caaagatagg ctcgctttcg cctgcaaatt caagagttcc
    12661 aaaagactgt gccatatctg gcacgacata tttcatttcc atattgtttt acctcgtttc
    12721 tttctatatt tgataagttt atgattgtaa ttttttattc tggcttgtct gccgtttgac
    12781 agtttcggcg gagaacgtga tttttctttc atcataccgt taccgcctta tgattttttc
    12841 attgtacggc gtttgtaaag atatgttcca gccagtccac cagcagatgt aagcaacatc
    12901 acaagaaatg ccatgacatt tgtactgtcg cccgttttag gactgtcgct aggtctgttt
    12961 ggcttttctg gtgtctgcgg tgtttcgagt ttctctggga cttctggttt ttcattaaaa
    13021 gtaatcgtct gtccctcgtc ctcaatatcc ttatgctcgg taactttctt cggctcgtct
    13081 ggattgctta aatcatacaa ttcttcaaaa gttacaagct gtttgccgtc aagggaagta
    13141 gcgtcaaagg taaaggcaac ttccgctttc atagtttcgc tgtcagcggt aaaggtgtaa
    13201 tcactttcca cacgtttccc attgataaga agttctgcat tttcttcttt caacatctgc
    13261 cagcctacaa gtttgtactg tgtaccgact tccaagccct ctaaggttac ggtatcaatg
    13321 attgtaacgt cttttccagc ttcaatctct ttgttgccgt ctttgtcggt agcagtcgta
    13381 tgtatcttga tgatacgttc tgtaatcaat acagtttgtc cgtcgtcctc aatgtctttg
    13441 tgttccgcaa ctttcacggg ttcgtctgga ttgcttaaat cgtataattc ctcgaatgtt
    13501 accagatttt taccgccaag ctcggacgca ttgaatgtat aagaaatttc cactttcatt
    13561 tcttcatcat cagcgataaa agtatagtca ttttccacac gttttccgtc aatgataagc
    13621 tctgcatttt cttcctttaa catctgccag cctttgagct gatattttgt accttttgta
    13681 agcccgtcta atttgacagt atcgacgatt gttacctctt ttcctgcaag gatagtcttt
    13741 tcgctgtctt tgctggtcgc tgtggtatgg atagagattt ctttttcgta ttcatcagtc
    13801 aaagtcccta aatcaatcac aaggttattt cttgatacca cgatttcaaa aggtgggata
    13861 agttcaaagc ctttgttact atcgcaacgc atttcttcaa tgatgtaagt atcataaggc
    13921 aatgcacctt tgctgtcgtc tgcttcagaa gttccaaacc acacaccgtc ctcgctggtc
    13981 ttgcctgcgt tagtattgtg cttatgagaa gtccattcag cagaagtgga gaattgcccg
    14041 ttatcatcag taactacaac atgactttct cccgtcgtct tgcttgtgat cctaaaggga
    14101 acatcagcaa gacgcttgtg tgtgcctgca ccgattttca ctccctcaat atccccacgc
    14161 ttaatctgat tgtagataga gtgggcttcg tcggttaagt ccacgatttt tccattctct
    14221 gtgattgcaa agtcaatcgg cttcgcaccg tctgtcaagt aaccgtcggg agcttcactc
    14281 tcaacgatac ggaatttccc ataaggtaaa aggtcagcag aagtagaagc cacaccctca
    14341 atatctgtac gaattgtctt taccacttca tttttcttat atagcttgcc ctcaaccaaa
    14401 acagaattgt catttaagga aatgacgtca aaagcagtat ctttcaaagt ggcacttcct
    14461 tgtggtttgg tatcgctcgt ttctaaatct cttttctgaa ttttcacacc gccacggata
    14521 accttgtctg atacggaaaa ctggttactt cccgtcaata cagcaaggtc gccgtcctct
    14581 gtaatttgtg taaggtataa gccttttatc tgttcagact tatcgccagc ctgcatatat
    14641 gcaccgtcca gcaagtagcc gtttggagct tttgtttcct caacagatag tgttcctaaa
    14701 ggaagaatcg ctttgccgtc ctgcatatag aagctgtcgc cagatacctt gtaagcgtcc
    14761 gctaattttg tgatgtagtg agttgtcccg tcactgtctg tttcagcgat tgtctttgta
    14821 acccatgtac gagtagcttc ggcagggaga ttgtctttgt tatagaagcc agcataatac
    14881 ttccatgtaa actctgcacc ctctaaagaa gcgtttccct gcggattgtc tttctgcgtt
    14941 tccatatcaa tcttgaaaag ctcaatcaag gtgtccgtta cttttggtgt atctgatacg
    15001 ttcaaggtcg ctgtctttcc agcttcaact tttaaggaat acacggttgt atcaacttta
    15061 tatcctgctg gtgcggataa ttccctaata tagactgtac ctgcttttac ctctacaaca
    15121 tctgtatttc cgtttttatc agtcgtaagg gtggcaagct gtttcgtgca gtccttatca
    15181 gaaaagacac cataggtcgc accagcgatt gagtaattcc cgttaccgtc tgtaatgctg
    15241 gtattactgg aagtcttttg cagttttgca tttccgacat ttaacttcgc ccagaattgt
    15301 cccaattcct gcccctcgcc agagtagata taaccgccac attcatagcg tcctttattt
    15361 tctttcacaa aggctttagc accagcgaaa acttcgtcct gagttgcttt tggtatttca
    15421 tcataagaag ctcgcacgtt gtcgcattgc cagccaagat gtacgctcaa tctctgccag
    15481 acaacacatt gttccaacag atagacttgc ttgtagttca attccttgtg tgcttcgcca
    15541 tactgtttga catactctaa ggataacgcc acatctgaaa tctggtcggc actcatacgg
    15601 gtgcttgcgt cagctctggt cttgtagcca ttcttaaaat ctgtattgat gtctatacag
    15661 taagcgtcct cgccctcaac agtcaaatgt ccctcgttaa aggtagaacc aatcgaaccg
    15721 tcattcatta ctttttctac gataccgaca cgttcctctg attccgtcca gtattgcttg
    15781 ctttctgcat ggacggcggt actcggtaaa gcagtaacga cagtcgcaaa ggcaagtact
    15841 cccgtacaca atcgtttcaa tatctttttc ataattctaa atgctccttt cattttgggt
    15901 aaaaaaatag acgctcaata ttgaacgtct tacattgaaa agggatactt tttacaagta
    15961 cccctcaaat ctaatattta attgtttgtg ttcccacact ctatatcaac aactactgaa
    16021 acattgatat agttttttat ctctttattt ctgattttat cgccctcgct cgtaaagact
    16081 atatgcttaa aaaagtgcct aaaattaagg atttctacat agttcgtctt tgtagcaaca
    16141 cacaagtctc tatatgtgta gaatgaggga acatatctac aggttgtgcc tcaacacatt
    16201 taaatccgtg aacatttaga taatctaaat cccttgctaa agtagaagga ttacaagaaa
    16261 catagacaat tctttccgga ttcattgaaa caatagtctc taataccttt tcgtcacatc
    16321 cctttctagg tgggtctaca acgactacat tggcagtctt accctctcta tacatcttag
    16381 gtacaatttc ctctgccttt ccaacataaa attcagcatt atgtatattg tttaatttag
    16441 catttatctt agcatctttt atggcatcat ctataatttc tattccataa acctttttag
    16501 ccttttgtgc caaaaataaa gatattgtac ctatcccaca gtaaatatca aaaacagtat
    16561 cagtatcatt taaatttgca tattcaagag ccttatcata caatacttta gtttggacag
    16621 ggtttacttg gaaaaatgat aatggtgaaa tctcaaacac taagtctcct atataatcgt
    16681 ttatttttcc atctccatat ataactatat tttctcttcc tagaatagca ttcgtatctt
    16741 tttgatttac atttacaacc aaagtcttaa atccaggtat attttcctta agcactgaag
    16801 ctaattcttt aagatatgga agtttgtttc catttgctac taatacaacc attacttctt
    16861 tagttgtaaa acctattttt gttactaaat gcctaatcaa ccccgtgtga gtcttttcat
    16921 catatatgct taccttatag gcccttatat atgtttttat tattttaaca attttatcat
    16981 ttatctcatg ttgtattacg catttttctg tcgatattac atcatgagtc ttctttttat
    17041 agaagccaat aattggaata ccattattct tttgtattgg aaattgtgct ttatttctat
    17101 atctatatgg attatccatt cctatagtgt catgaacttc tacatcctct aacttaccta
    17161 ttctcgaaag tacttgttta acttcatttg ttttcatttc aagttgttta ttataatcta
    17221 agtcttgtat ctgacaccct ccacaatccc taagattgtc actacacact cttttcaccc
    17281 tgaatggaga cttttctatt atctcaacaa tatctcccac agcataattt ttctttactt
    17341 tattaatcct aactttaact ttatcatgta ttaatccgcc ctctacaaaa actgtaatac
    17401 cattgtactt tcctactcct actccgcctt gaccaatgtc tactatatct acaatataca
    17461 tctcgttttt cgaaagcata aatcaccctc caatcaatct attatattta aatctttaca
    17521 aacttttttc tttaaattta tattaaaata ttgctattaa ttaaactata ttttttacta
    17581 agctacaata ttttatttta ccaaaaaaaa aggagcttat aaagcccctt agtaaataaa
    17641 tttattattt ttcttataaa actctagttg aacctctata taccacgcct cttgatgcat
    17701 ccacagttac aacttctcca tcttttacta gatttgttat atcagctgca gacacaataa
    17761 ctggtatatc taaatttata cctacaatag ctgtatgtga tgtcattcca ccattctcag
    17821 ttactacagc tcctgctttt tctatataat tgttcatttc agcatcagta gcagtagaaa
    17881 caagtatgtc gccttcatta aagtctacac aagcatttcc attctttatt atacgaactt
    17941 taccttctac tgtttgagta cctacaccta taccttgcac gatttcttcg cttattacat
    18001 gaacctttat taaattagta gttccactta ctcctactgg tactccagca gttataacta
    18061 ctaattcccc attatctata taatcagctt gtctagctgc ctcaattgcc ttttctataa
    18121 cttcatctgt atttcctgca acagaagact taactggata tactccccat gtaagagcta
    18181 atttattcat agtcttttca ttatttgtag tagctattat tggagatttt ggtctgaatt
    18241 tagataccat tctagcagta tatcctgaag aagtagatgt tattatagct gatgcattta
    18301 aatctactgc tgttgtacaa gttgcatggc ttattgcatc tgttacagta acattgttag
    18361 taccattttc ctttagtaat ctatcataat ctaaagtctc ttctgttctt tttgctattg
    18421 tagccatcat ttttactgcc tctacaggat attttccagc agcagtttct ccagataaca
    18481 ttatcgcatc tgttccatca tatatagcat tggcaacgtc tgtaacttct gctcttgttg
    18541 gtcttggatt tcttatcata gaatcaagca tttgagtggc agtaacaact ggctttgcta
    18601 attcattaca tttttttatc atcatttttt gaactattgg catctcttca gttggtatct
    18661 caacacctaa gtcacctcta gccaccatta taccatcaga aacttttaat atttcatcta
    18721 ggttctctac accttcttgg ttttctattt tagatattat ttgtatatca gttgcattat
    18781 tgttctctaa tacttctctt attgctagta catcagatgc ctttcttaca aaagaagcag
    18841 ctatataatc tattccttga cttattccaa actctatatc acttatatct ttaggagtta
    18901 ttgctggtaa atttatctta acaccaggta catttactcc tttatgattt ttaactattc
    18961 ctgaattttc aacaacacaa actatatctt ctccatttat ttcttttact cttaagccaa
    19021 ctaaaccatc atctattagt atagaatctc ctgatttaac gtcttcagca agacctttat
    19081 agcttactgt acacatttct ttagtcccca taatatcttt catagttata gtgaactttt
    19141 gcccttcttc taaaaatacc tctgggtctt caaagttacc tgttctaatt tctggacctt
    19201 tagtatctaa taatatagca actggcttat ttaatttttc tctaactttc tttgccatat
    19261 caattctttc tttatgttct tcatgcgaac cgtgagaaaa gttaaatcta cacacattta
    19321 gaccattttg cataagttga gttaaaactt cctcactttg tgatgctgga cctagtgtac
    19381 aaacaatttt tgtcttcttt acattattta acatatttgc tcctcctgag atattattcc
    19441 acagatttat ttttaatact aaaacttata tagataatat ttttgccatc tcataagctt
    19501 ctttatcaaa tactttcttt tgagctaaag cttcacttat ttctaaatca attattttgt
    19561 tttcttttat tcctacaact ctagctgatt ttccatctaa taataattct actgctctta
    19621 ctccaagtct acttgctagt attctatcag atacagttgg gcttcctcct ctttggacat
    19681 gccccaatac agtgactctt aaatctgctc ctgactcttt tttaagttcc ttttctaaat
    19741 cactagcact tccgactcct tctgctaaaa cgattatact atgtctctta cctctttttt
    19801 gagtagtctt taatcttaga gcaacttcat ctactgtaat ttctacttct ggtactatta
    19861 tagtttccgc tcctcctgca agacctgcat ataaagctaa atctccacag tgtcttccca
    19921 taacttctac tatgttaact ctttcatgag atgatgatgt atctcttatc ttacctatag
    19981 catctataat agtattcatt gcagtatcaa atcctatagt ataatctgta tatgctaaat
    20041 cgttatctat agttcctggt atgcctatag ctgggaatcc taagtcacta agtttttggg
    20101 ctcctgcaaa tgaaccatct ccaccaatta caactaagca atcaatttta tactttttaa
    20161 gaatttttac tgcttttaat ctaccttctt ctgttttaaa ttcttcacat ctggaagatt
    20221 ttaatatagt tcctcccctg tgtataatat ctccaacaga agataagttc atttcagtta
    20281 aatcttcttc tagtaatccc ttatatcctc tattgattcc atatactttg catccataat
    20341 atattgctga tcttacaacc gctctaatcg cagcattcat tcctggagca tctcctccac
    20401 ttgttagtaa tcctatagtt ttcatttttt acctccttgg attttatgtc aattttttat
    20461 tataatcatt gttattgtat tctaatggac tttttttgtc cctatatcac tttttaatcc
    20521 catcaagact aaaaaaatta aatgtcctta aatgtccatt ttgtgatatt atatcacaaa
    20581 acggacaata tttttcatat tattataata tatttagatt tttatataaa aaatcaagct
    20641 tttactttta tgttatcttt aggaagtaac tcttctaagt tatttataaa ttcatcacat
    20701 atacaagtca atgccccggt cattttatat gctttacgtt taccatttat attttcatcc
    20761 atagggtata agtatatact gtcattacct ggatattgtt tggctatttc tacaatatta
    20821 ttagttgtat cagtatcaga catactatct attttcaaat acaatttttt accactttct
    20881 ggcttaatat tttctacatt tctagttctt cctgaattgt agtttctatc tgcaaagtca
    20941 gtatcatcat ttatatcttt tatctctcta gctataagtt ttgcattttc gccttctttt
    21001 atacttaatg ttccttttac atatattata ttatcttcat tcaaaatgac attatacttt
    21061 tgtaataatt gaggaaaaac tattatttct atagcaccat acaaatcttc taattcaata
    21121 aatgccataa tttcatttcg ttttgttgtt ttaatagttt tagttacaat cattccaccc
    21181 attataacat ctgtttcatt catttgtagg tatgactctt cttcctcttt taatgaattt
    21241 aattttccat tatccataga tgttttttct tgtagttctt tttcaaattg tgataaagga
    21301 tgtccactta catacattcc caagacttct ttttcaaggt taagtctctc tctttcttcg
    21361 tactcttgcc ttttaggcaa actgtatatt tgttgaaaat cactatcttc ctcactatct
    21421 ccaaaagcat caaataaaga aatttgacct tgaacatttt tctttctatc catagataca
    21481 ctttctaata aactttcata accagccatc agactagctc tattttcact tatattatca
    21541 aaagctccac attttattag actttctatt actctcttat ttgtatcttt ttggtctaat
    21601 cttttgacta aatctactaa atctacaaat aatccattag attctctttc agcgattata
    21661 ttgtttatta tatttacgcc aacatttttt acggctgcta gaccaaatct tatattgtcg
    21721 ccttcaactg aaaactttga aaaacttttg tttatatctg gaggtaatac atctatttct
    21781 agtgctttac attctcttat atactcaact accttatcag tatttcccat tacactggtt
    21841 atcaatgctg ccataaattc aactggataa tatgttttta gataagctgt ctcatatgct
    21901 aaaaccccat atgcagctgc atgtgattta ttaaatgcat atctagcgaa gtctatcata
    21961 tcatcaaata ttttattagc tatttcctct tctacaccat ttctgataca ccctgcaatt
    22021 tctatattac catcttcatc aaatttacca tgaataaaat attgtctttc ttcttccatc
    22081 acgtccatct ttttcttact catggctctt ctaactaggt cacttcgtcc gtaactataa
    22141 ccacctaaat ctctaacgac ctgcataacc tgctcttgat ataccaaaca accatatgta
    22201 acttccatta taggctttaa tttttcatgt agatatgtta catcttttgg gttgctttta
    22261 ttttttatat atgcaggtat agaatccatt ggacctggtc taaataggga tattcccgct
    22321 acaatatctt caaaattgtc tggttttagc tgtttcataa aacttctcat gccagcactc
    22381 tccaattgaa acacccctag tgtatttcct gatgaaagca tttcatatac tttcgggtcg
    22441 tcataatcca tctttgaaaa gtctattttt tctgtgtaat tttttataac tctatttttt
    22501 tctattaaat caagagtatc tcttataact gtaagagttc ttagcccaag aaaatccatc
    22561 tttaaaagcc caagttcttc aagtgttgtc atagtaaact gtgttgtgat tgcatcttga
    22621 tgtttgtaca aaggtacata ttcatctacg ggattttttg atataacaac tcctgctgca
    22681 tgagtagaag catgtcttag cattccctct atctgttttg atatatttat tatttctttt
    22741 gtttccgggt cttggtcata caattcttta agattaggat ttgtatctag ggccttatct
    22801 attgtcattc ctaaagcaaa tggtatttcc ttggctacct tgtcaacttt attgtagcct
    22861 atatccaata cccttccaac atctcttatt gcagcttttg cacccattgt tccaaaagtt
    22921 attatctggg ctacatggtc atcaccatat tttctcttta cataatctat aacttcttct
    22981 cttctctcat aacaaaaatc tatatctata tctggcatgg atatacgttc tggatttaaa
    23041 aaacgctcaa ataatagaga gtactttatt gggtctatat cagttatttt aagtgtatat
    23101 gctactatcg aaccagccgc actacctcta cctggtccta ctataatatt attttcttta
    23161 gaaaaattta taaaatccca aacaattaaa aaatactcta cataacccat tttttcaatt
    23221 acatctaatt cataatttaa tctctctagt atctcattac taggattatc atatctctct
    23281 tttaatccat taaaacacaa ctcccttaaa taagtttctg gtgtatatcc ttctggaaca
    23341 tcatacttag gaagatgtat agtattaaaa tcaaactcca cattacacat atcagctatt
    23401 ttcacagtat tgtcaatagc ctctaatgca tatggaaata attcttccat ttcttctctt
    23461 gattttaaat aaaactcatc actaccaaat ctcattctat ttgggtcatt taatgttttt
    23521 cccatttgaa tacacataag tacatcatgt attttcgaat cttctttatt tacatagtga
    23581 acatcattag tagcaactag tggtatacca gtctcttttg ataattttac taaaccagag
    23641 tttacttctt tttgctcagg taaattgtga tcttgaatct ccaaaaagaa attttcttct
    23701 ccaaatatgt ctctgtagtc aagagcaaat tgttttgctt tttcataatt tctattcatt
    23761 aaagcacgtg ctacatctcc tgcaaggcat gcagaaagtg ctataatccc tttgttatgt
    23821 tttttaagtt cttccatgtc aactctaggc ttatagtaaa aaccttctac gtatgaagtt
    23881 gaaactattt ttattaaatt tttatatcct tccatattct tagctaacag aactaaatgt
    23941 ccttgatatt tgtcatagtt tgggtcttta tctctcaatc cacgtgcagc tgtatagact
    24001 tcacacccta taattggctt tattccttct tttatagctg ttttgtagaa atctataaca
    24061 ccaaacatac aaccatggtc agttatagct attgagctca tgtttagttc cttagccctt
    24121 tttataagtt ttttcaccct cgaaaaccca tcaagtaaac tatactcagt atgtacatga
    24181 agatgagcaa aatctttgtt cattaaatca cctcctgctt tataatttta attttaccac
    24241 aaatatatgt cctaaaacaa aaacagagac ttttatctca aaataggaat taacttcaac
    24301 atataccatt atatgttata aattaatgct tattctgaga ttgtcccctc aatttattgc
    24361 tatgattttt ttttcaaatc tgttgcaatt tcttctattt ttctaagtct atgattgact
    24421 ccagattttc ctattggtgg ttctaacatc tctccaagtt ctttgagagt catatcctca
    24481 tactcgattc taatcttagc tatctcttgt aaattttctg gcaaactgct aattcctata
    24541 gtctcttgta tgagcttaat attttctact tgtcttactg ctgcatttac tgttttagaa
    24601 aggttagctg tctcacaatt tactatcctg tttacattat ttctcatttc ttttactatt
    24661 ttagtatttt gaagacttaa aagagcgtgg tgtcctccta taatactcaa caaatctgat
    24721 atttgttcac tctctttgat ataaacaacg tgattatttt ttctagccac aattttacta
    24781 ttaaaaccta aagagtttat aagttctttt agagaatctg caaactcctc attattagtt
    24841 acaaattcca tatgatagtt cttttctggg tcgcttatag aacctccacc aagaaaagct
    24901 cctcttatga aagctctctt acatccttca tgcttaatta agttctctga aattttgttt
    24961 atagtaaaaa atccttcttt atcttcaagt atacctaact tttttaataa catttctgaa
    25021 cccatttcgc ttgttaccat taatacataa ctgttatttc tctttagcat ttgattctta
    25081 tttactgaga ttgtagtatt gatattaaaa ttctttttta ataatttaaa tactttacgg
    25141 gctattgaat ttaactctgt tgttatcttt agatttagct tcttatatcc aacaatttgt
    25201 atacttcccc ctgatttaac tagagctgac aattcagcta tattacaaca ttcattccca
    25261 gatataactc ttgctagttc atttttggtt tcagttgaaa aagacatatc tatcacctat
    25321 taactaattt ttctttaacc ttttttttat ttcttgtaag gcaaccttta ttatctcctt
    25381 ttcatcatca tacctagcta agtctactac tctatctagg tggataaatt tagcatcaat
    25441 aaagccttcc tctttttgtg gaatagtatc catattcttt gcttgcatca aataccaaaa
    25501 aactgtttta tgaactgctc tattttcatc ccagttttct ttgaatgtat agtgtatttc
    25561 acctaaatat ttcaatatat ctgcttttac tccagtttct tcacttactt cacgtaatgc
    25621 tgcctcttgg ttattttccc cttcttctac ttttcccttg ggtaacaccc aatctccatt
    25681 gaacttcctt agtaaaagaa tcgtattgcc aaacaggact acaccaccag cactaacctc
    25741 ttctctcatc gatgttcact ccttaaaact aacataatga taaggatttc tacacaattt
    25801 tttaaaatcc ttttttacta acttttgttg taattatgat ttagggctaa ctcaataact
    25861 atgttagata tatactttgc atcatgtctt atataattat tttttatttc aattaaattc
    25921 ttctctacag tttttatacc catctctttt aatttatctt tttgcttttt atctaacaag
    25981 acttgctctg ctccatcttg tttatataag tcaagcattt cttctggcaa tatctcatta
    26041 tttgcgatta cataatctat taaattctca tcagtgtgtt ttactatagc attaacatgc
    26101 tctaatacat tgtacccttc tgtctcacct ggttgagtca ttatatttgc tatatatact
    26161 tttggagcta cagacgattt aatagcgtct acaatcccct ctacaagtaa attgggtatt
    26221 atacttgtat ataaacttcc aggacccata attataatgt cagcatcata aatagatgca
    26281 ataacatcct ttaatggttt tacatctttt ggatttaaaa aaattttatc aatagagctt
    26341 ttttgaattt ttgactcttc aggtatacta gattctccat ttattatatt gccattttct
    26401 aatttggcaa ctaaatttac atcttccaaa gttactggta aaactcttcc tgttatagca
    26461 aaaatttcac ttaatttata tacagctttt tcaaagtttc catacaaccc attcatagca
    26521 gccaaaaaca aatttccaaa actctgacct tttaaaagcc cttctgtaaa cctatattgc
    26581 ataacttcat tcattgttgg ctctatattt gcaagtgcta ataaacagtt tcttatgtct
    26641 cctggtggga gcattcctaa gtcttctctc aatacacctg aacctccacc atcatcagca
    26701 acagttacaa ttgcagttat attttgcgta gtgtgtttaa gacctcttaa aaataccgat
    26761 tgaccagtac ctccacctat cacaaccaca tttggttctc tattttcaac aatagacctt
    26821 tgaaatagtt ttactttttc attttttgct tttttatata taaataacga tacaattaat
    26881 gcaatccaac ctaaaattcc tacaataata agtaatttag ccatgtttgc ctccattatc
    26941 gcaacataga gtctctatgt ttctttacaa ctctatatcc cttattagat aaatcctccg
    27001 ctataagatt tgttatagta actgacctat gtcttccacc tgtgcatcca acaccaatta
    27061 ctagatgttg ttttccttcc tctatatatt gaggtactaa aaaatgaatc atatctaaaa
    27121 gtttcacata aaattcttca ctgattttag aattcataac ataatctcta acttctttat
    27181 catcaccagt tttagctctt aactcttcaa cataataggg atttggaaga aatcttacat
    27241 caaatactaa atctgcatca gcaagtatac catgtttaaa tccaaaagat actacagaaa
    27301 tagttaggtt tggattatct tcacctgaag aatatatttt ctttatttct tccttaaggt
    27361 ctttaggttt catgttagtt gtatcaatta tacatgtaga taactccttt aaaggttcca
    27421 ttatctttct ttccattttt ataccttctg gaatctgcat atcttttgcc aatggatgat
    27481 ttcttcttgt cattttatat ctctttaaca atacatcatc attacaatcc aaatatacca
    27541 tttcatattc ataattttct ttttctaaat aatttaagct ttcatgaagc gcttcaaaaa
    27601 actttctccc tcttatatct atccctagag caactttatc aatacttgaa tttggttgat
    27661 aacataattc tgcaaattta gttatcaaag caggaggtag attatctaca caataaaatc
    27721 ccatatcctc taaagctctc attgtctcac tttttccaga tcctgaaaga cctgtaacta
    27781 taacaaattt cattgctaac tcctcccttt tatcttatgt ttattatatt ataatgtttt
    27841 ctactaacga tatatccaga ttagagtcag atatagtctt catagctagt tcaaaatcac
    27901 caactctttc tggacaatgt gcatctgagc ctattataaa tttattttct agccctttta
    27961 ttttatttaa ttgatttaca ttcaaaaaag aatggctact atttatctca agtctagtat
    28021 ttgtcttttt tgctgtcttt gctacttctt ctatatacac atcgccttta tctcctggat
    28081 gagtaattat aaaaatatca ttattactta tcgcatttat tacagctttt gtattatatt
    28141 cttttgcttt ttcagtttta aaaatatagt tattacaatg atttaataag cttcttaatg
    28201 atgttggagt agaaccaaaa tgatatccag ccataatata atcaaaatct ctaataaatt
    28261 tatcatccat atctatattt cctttatcat ctaatatgtt acactccata cctaaaagta
    28321 tatttatatc agtgtactta tcatttaaat aatctacttc ttctctcatt ttgagaatat
    28381 cttttttctt tacaccatat gcaatatgtt tataactatg gtcagatatt cctattgttt
    28441 ttattccttt agaaatggct acctttacat tatcctcaat agtccctttg ccatgactat
    28501 ataatgtatg tgtatgataa tcagccagta ttttcatttg ttaatcctct ccaagtattt
    28561 tgacttcttc ttccaacata accccaaact tggcatatac agcacttttt ataacatata
    28621 ttaaatccaa aatatcttta gcacttgctt ctccttgatt gactacaaat ccacaatgct
    28681 tctcagatac ttgtgctcct cttaaagtaa gacctctcaa tccagtttct tctattaatt
    28741 tacctgcaaa atatcctgtt ggtctcttaa atgtacttcc tgcactagca aaatttaatg
    28801 gctgtttagt tattcttctc gtcgctaaat catccattaa actttttatt tcatcataat
    28861 ttccttcttg taattccaat tctgctgata aagctatata tccgtttttc gatattatac
    28921 tttttctata cccaaattcc atctgttcat ttgataattc aaatatattg ccttccatat
    28981 ccatcagtct tactgacttc actatgtcct tcatttcacc accatatgct ccagcattca
    29041 tggctaatgc tcctcccaat gtgccaggta ttcctgatgc aaactcaaac ccttttaatt
    29101 cttgcttttg gagagctttc cctaaaactg ataataaagc tcctgactga gcagtcatcc
    29161 tagtatcatt tatctcataa gaattgaaat tatcagctag ttctattacc actcctctta
    29221 ttccaccatc tttaattaaa atgtttgaac catttccaat tattaaatac ggaatagatt
    29281 cttcttttac caacttaagt acatttttta attgttcttc agttctaggt ctaactaata
    29341 tatctgctgg tcctcctacc ctaaatgaaa tatgtttttt cataggttca tcgactttta
    29401 tatcctcttt acttaatata tttaataaat ttatatatat atcttgatta ttcattgtat
    29461 ttcctcccaa attatactga actttagctg tcattattat ttaaattaca ttagtatata
    29521 gtattaacta tattcaataa tatatgattt tgcttatcat atggatttta tattttaagc
    29581 ttcttaatta caaactatat tcaataaata tataataaag taaaaaaaaa aaaataacaa
    29641 catataaaag aatataaata atttaaaaaa agcatcaata tcactgatat caatgcttta
    29701 aaaggcaatt taattcgtat tatttatcta actatttttg acatagcaaa gataataaat
    29761 ccctccaact actatggaac ctccaacgat atttccaagc gttacaaata ccaaattagt
    29821 tataaattga accatagtta tatttgctcc taatgccatt cccattggta taaaaaacat
    29881 gtttgcaaca ctatgttgga atccacataa tacaaatagc attattactg tccaacatga
    29941 agccaatttt gacattatat cttgagatgc tgtagccatc catacagcta aaacgactag
    30001 aatattacaa agtattgctt ttaaaaacat tgatgctata gttgaattaa ccttagcttc
    30061 tgccacagct atagcttttg tagctgcatc tcctgtcaat gtagaagaat aaaacacaag
    30121 tgcaactagc aaaattgaac ctactaaatt tgcaaaataa accagtcccc agtttcttaa
    30181 catttttcct aatgttattt ttttgtccat aagtgcaata gccattaagg tgtttccagt
    30241 gaataattct gctcctgcca ctactacaag cataagacct actggaaaga ccatagcact
    30301 taaaaagcta gctacccctg ggtctatctt gccaaaagtt tgactaacta tcatactccc
    30361 caatgcccca aaacctataa atgctcctcc aaataaacct aatagaattg cgttttgtgt
    30421 cgaaatattt gcttttttaa tgcctgcact tatagttgct tgtgcagttt ccccaggtgt
    30481 caagaatcct ttactcataa atccttcccc cttaaaaatt atactttccc ttgtcttttt
    30541 atggcaataa ttatataata acaatatgat atataataaa ttttattaac ataaaaaata
    30601 tactatatac ttatatatac ttgtctcata taattatact atttattata taacaacttt
    30661 gttaatttcg aaataattta tattgaattt gaaaaattta ccttttgatt atttatttta
    30721 ctttttaatt attgaggtat tatatataat agatatatgt ttgtgttatt atatataatt
    30781 acttatttta ataaatattt gaaggaggga attttatgtt tgatatatca tttttcgaaa
    30841 tgtcaatata tgaaatagca gttactacaa tatatataat taatttcatg gttatactaa
    30901 accttatctt tagagaaaaa agaaacataa atacaacttt aacatggctt cttatattag
    30961 tattgattcc tgctcttgga ttcatacttt atatagcttt tggcagaaat atttcaaaaa
    31021 acaatatgtt tagattgaaa gaaaaggatg ataagataat caaaagtaat atactagata
    31081 ctcaggttaa actccaatct acatctgaaa ttgattcaga tatacatcaa cataaggata
    31141 tgatttatgc attggctaat tcaaataatg ctcattatac caataataac gatgtgtgga
    31201 tttatgctga atctagtcaa ttttttaaca gtcttcttga agaacttaaa aaagctaaaa
    31261 aatatataaa catacaattt tacattttca aagatgacaa aatcggaact gaaataatag
    31321 acattcttat agacaaagct aaagaaggtg ttgaagtaag acttttattt gatgcagttg
    31381 gtggtagaac actaaaaaat agtacacttt ccagacttaa agaaagtggt gttaaagttg
    31441 gaagcttctt cccatcattc ttgaaaattg taaactttaa cttaaactat agaaatcacc
    31501 gaaaaattgt tgtcattgat ggtaaggtag gatttgtagg tggatataat gttggtgatg
    31561 aatatttagg tagaaatcca aaatttggtc tatggagaga tacacatact aagcttactg
    31621 gtgattgcgt aattgaccta aatatgagat tcatccttga ttggagatat acaactaaag
    31681 aagacttaga tttagaaaag tactttatag aagaagatac aaattctaat catccttctg
    31741 aaaatattgg gattcagata gtatcaagtg gtccagatat atcagaactt gatgagatta
    31801 aatatggtta ccttaaaatg attcagaaag ctagaaagta tatatacata cagagtcctt
    31861 atttaatact tgactcaact tttatagata ctttaaaaat agcttgttta tctggtgttg
    31921 atgtgagagt tatgattcct tctaaacctg accatccctt tgtatactgg gcatcatatt
    31981 catatgctgg agaactttta aagtttggag ctaaaatcta tacttatggt caaaatgcat
    32041 ttttacatgc taagacaata gttatagatg actctatatg ctctatagga acagctaata
    32101 tggatatcag aagttttgag cttaatttcg aagttaatgc atttatgtac tcttcaaaaa
    32161 aagcattgga acaaagaatt atatttgaaa atgatatttt aaattctaag gaaataacat
    32221 tagatatata taattctagg tctacttata taaaaatcaa ggaatcaatt tcaagactat
    32281 tatcagcagt tttataaatc ttttatttta taaaaatttt acattttggt ttatttttta
    32341 aagtttttta tatgtattat ttttttttta ttgaatttag ctcatttttt ttattttttt
    32401 taactattct gaattatttt atattataat agactagtat agtttttatt tttaataggt
    32461 aacttttttg cattgttttt ataaataaag aaattgttgt atattattct ttctttattg
    32521 ttttggtttt gttcacccac ataatgttgg ggtcaactca tggttaatta ttttatgaaa
    32581 aataataact ttaaaaagaa aagggggatt tgttatgtgc gattttattt cacacaacaa
    32641 gcaattattt gacgaactag atatatttat tgactctctt gcaacaaagg aaggtgcgtt
    32701 aatacaagtt ctacatgaag cccaaggtat atttggatat cttccaaaag aagttcaact
    32761 tcatgttgct agaaaacttg gagtagctcc tgcaaaggta tatggggttg ttacattcta
    32821 ttcttatttt actacagaac ctgtaggtaa gtataaaatc agtgtctgtc taggaactgt
    32881 atgttttgta aaaggtgctg acaaaatctt aagtgctttt gaaaaacagc ttggcataaa
    32941 agttggagaa actactagtg attttaaatt ttctttagaa ggtttaagat gtttgggggc
    33001 atgtggttta gctccagttg ttactgtaaa tggtaaagtt tatggtaaag tgaaacctga
    33061 ccaagtaagc gaaatattag atacttatag agaattagaa ttgaattgtt aagaggggtg
    33121 aataaataat gcgtaaagta aattcatttg atgaattaaa agttttagct gatgagctga
    33181 aacctaatct tagcttaaga aaaaattatt ctaaggaaaa tgtattaaga agagaattac
    33241 ttgtttgttg tgatactgga tgtacatctt caaacagtct agaaatagtt agtgaattag
    33301 aaaatgaaat aaagaaatca ggaatccaag ataaagttag tgttcgtttg acaggttgtt
    33361 ttggtttctg tgctcaaggt cctattgtaa aagtttatcc tgataacgtt ttctacgtaa
    33421 aagttgagcc atctgatgct gaaaagatag ttcaaagcca cttaattaga aatacagttg
    33481 tcgaggaatt attatatgag gaagaatctt taagtaaaaa agttgaagaa caagaagaaa
    33541 tgtctttcta caaaaaacag ttacgtatag ctttaaaaaa ttgtggtctt atagacccag
    33601 atagtataga agaatatatt gccaatgatg gttatttagc tctaggcaaa tgtttaactt
    33661 ctcttactcc tcaagaagtt attgcagagg taaaaacttc tggccttcgt ggtagaggtg
    33721 gtgcaggttt ccctactggc tctaaatggg aagctgcttc aaaaaatcca gctggtccaa
    33781 cagataaaaa gtttgttgta tgtaatgctg atgaaggtga cccaggtgca tttatggata
    33841 gatctgtact tgaaggtgac cctcatagtg tactagaagc tatggcaata tgtggatacg
    33901 ctataggttc tgatacagga tacatataca taagagcaga atatccaaaa tctatagaaa
    33961 gattaaaagt agccatagct caagctgaaa aatacggttt acttggcgaa aatatcttag
    34021 gcactggatt taactttaaa ttagaattaa aatatggtgc aggtgctttc gtttgtggtg
    34081 aaggtacagc gctaatgcat tcaattgaag gtagacgtgg tgaacctaga atgaaaactt
    34141 atagttcttc taagagtggt ctatggaaat ctcctacttg cttaaataac gttgagactt
    34201 ttgctaacat acctgcaatt atacttaagg gtggagattg gtttgccaac ttaggtactg
    34261 aagattctag tggtactaaa gtctttgctc ttggtggaaa agtagaaaat gtaggacttg
    34321 ttgaagttcc aatgggtact actttaagag atattgtatt tgaaattggt gggggaatcc
    34381 ctgaaggtaa gaaatttaag gctgttcaaa caggtggacc atctggcgga tgtataccaa
    34441 ctgaacattt agacactcct atagactttg gttcattaag ttctatcggt tcaatgatgg
    34501 gctctggtgg tatgcttgtt cttgatgaat ctgactgtat ggtagatata gccaagttct
    34561 tccttgagtt tactgttgaa gaatcttgtg gtaaatgtac accttgtcgt ataggtacta
    34621 caagattatt agaaatatta actaaaatta cagaaggtaa tggtactcta caagatttag
    34681 atgacctaga aaaccttgct gaaactatac aaactgcttc attatgtggt cttggtaaag
    34741 ctgctccaaa ccctgtttta agtactcttc aatatttcaa agatgagtat atagctcatg
    34801 ttgtagataa gaaatgtcct gctggtaaat gtcagaactt actttcttac tttataacag
    34861 atgactgtaa gggttgtaca aaatgttcta gagtgtgtcc tgctggttgt ataacaggtt
    34921 ctgttaagga acaacataca atagatactt ctaagtgtct aaaatgtggt gcttgtatag
    34981 ataattgtac atttaacgct ataatcaaga aataacttat ttggaggagg aataacaatg
    35041 agtttagtta atttaactat taatggcaaa cacgtttcag cacctagtgg aacttctatc
    35101 ttagatgctg cgaaattaat aaatataaaa atacacaacc tttgtcattt acatatgaat
    35161 gaaatagata agcttgacac ttgtgcttct tgtcgtgttt gtatggttga gacagagaga
    35221 ggattagttc cagcttgtgg aacagttata aaggaaggta tgaaagttca gactaatagt
    35281 gctaaagcat taaatgctcg tagaactatt gttgaattat tgttatcaga ccatccacaa
    35341 gattgttttg tctgtgaaaa aaatggagat tgtgaattac agactatagc tgctgattta
    35401 ggagtaagaa aaataagata tcaaggttct aaatcttttg caggtaaaga tacttctact
    35461 aaatctttag ttaaagacca ttctaagtgt atattatgta gaagatgtga gactgtatgt
    35521 aatgacatac aaacagtagg agcattatct ggagttaatc gtggatttaa tactttagtt
    35581 agtacattct ttaactctga tatggttgaa acagagtgta cattctgtgg tcaatgtata
    35641 tctgtctgtc caactggagc attaacagaa gtagataatg tacctaaact ttgggatgtt
    35701 ttaaataaaa aagaaaagac tatagtagtg caagttgctc ctgctgtaag agttgctatt
    35761 ggtgaagagt ttggattaga accagggtca atctctacag ggaaaatggt agctgcttta
    35821 aaagcacttg gatttgaaca tgtatttgat acaaactttg gtgcagattt tactataatg
    35881 gaagaagcta ctgaatttat agaaagaatc caaaaaggtg aaaatcttcc tatattaaca
    35941 agttgttgtc ctgcatgggt aaacttctta gagcacaatt atccagacaa gttaaactta
    36001 gcatctagct gtaagtctcc tcaaggtatg tttggttcta tagctaaaaa ctactatgca
    36061 cctaaaatat taggaatcaa tcctgaagaa ctttatgttg tatctgtaat gccttgtgta
    36121 gctaaaaaat atgaagcttc aagagaagaa ttaagtgaat ctggaatact agatgttgac
    36181 ctttctataa ctactagaga gttagctaag atgataaaag aagctgcaat cgatttacct
    36241 aatcttcaag accaagattt tgataatcct ctaggaaaat ctacaggtgc tgcatctata
    36301 tttggagcaa gtggtggagt tttagaagct gccctacgta cttcatatga gaagataact
    36361 aataagactt tagataatgt aaacttcact aatgttagag gtcttaaagg aattagggaa
    36421 gcaagtatag atgttgatgg aactacagtt aatgtgtgta ttgtaaatac acttaaaaac
    36481 gctagaaaga ttatggataa ggtcagaagt ggagaatgta aataccatat catagaagtt
    36541 atggcatgtc ctggtggatg tgttggaggt gctggtcaac cttatcacca tggtaatact
    36601 gaaatagttg atagacgtgc aaatgcgtta tatgaaatag atagaaataa ggctattcgt
    36661 aaatctcatg agaatcctga tttacaagct atttataaag acttctttgg agaaccaaat
    36721 agtgatgtag cccataaata ccttcatact cattactttg ataagagttg tgtctatgga
    36781 gagtgtccac aagaatgtgc ttgtgaagaa gctaagtagt cataacaaaa tataaaattt
    36841 attcttaaaa aaggattgtc ttaaaatact tttacgtaat ttaagacaat ccttattaat
    36901 ttcacaaatt aaattatatt tctaaataga cttattcttt aattaaccta tctattaatt
    36961 aaagaatacc tgccattctc ataagttgtt ttgcatttgt agttttacat cttccatctt
    37021 ttatcttata gtcaaaatga attttatcgt ctacatagta ctctgagaaa tgatagttta
    37081 caacttcaac atctccacta cctgaaaggt cacatagctc aaagtcatgt gttgtcacca
    37141 tacttataac ccagggtttt gataatttct ttactgcctc acttgctcca ataattctat
    37201 cagcagagtt agttccctta aaaatttcat ctactagaac caacattggc agttctttta
    37261 aactatattg aatcattgat tttattctaa gaatctcagc atagaaagtt gatattcctt
    37321 gacttacatc atcttgtatt ctcatagaag taaatatagc catacaggtc gcatcaaaac
    37381 tcttagcgca tactggagca cctgcatatg ccagcactaa gtttacaccg atacttctta
    37441 aaaatgttgt ctttccagac atatttgaac ctgtgataat acaagtctga gaatttaatt
    37501 gtatcgaatt tgctatgaca cttttttctg ctattaatgg gtggtatacc tcttcaactt
    37561 tcaatcttgg agtatcttca tattttatta ctggaaaaca tgtattttcc tttacatgag
    37621 aaacaactgt taaacttatt agagcttcaa attctccaat agattcaaac caatctctaa
    37681 tttgatttcc atatatacct ttccatcgct ccaaagcttc tgcacaatga tagttccaca
    37741 tcaaaacacc acaggcaatt atatatagta tctgattata ccttaggttt acagcatttc
    37801 ctattgaatt taattgttta acacctcttg aaactccact tcccttagaa agtttatctt
    37861 gtaattcttt caaatatgca ctctcaaacg tctctttttc taaaacctca aacatttttt
    37921 catatacttg tatacttcta ctaaatgaaa ataatggagc aagagtttgc ataagtcttg
    37981 gatatccaaa accactaaac cctaactgga ttataaaaag taaaaaaaca ggtaaaacag
    38041 gtaaaaatcc taacatacaa aatataaaag ataagattgt tgcagttggt aaaccccaag
    38101 taaaaatatg catccatttt ggtatataca cattcttatt ttctccatat tctataaacg
    38161 attctatact actatctgaa ttgttttttt gctctttacc aattatatta ctgagtgttt
    38221 gaatatgaat agaaaaatca tcttttgata aaagttcttt tatagctctc tgtctttcta
    38281 agattacatt ctcatctgga ttttcattcc acaaatattt ggctaaaaaa tttttcccat
    38341 aagatgtatt agctacacag atatattgat acaatgatgc tcttccaaat aagtctaaat
    38401 cttttgcttg cgaattttca tcttttaagt attctttacc atctatttta aattccttcc
    38461 aaccatctcc aaatctctta atatacttat ttaatacttc gctcttactt ttaaaatatg
    38521 tttcttcttc ttttacttta ctatgaataa ctaagagtgc tataaatatt attattgata
    38581 aaactccaac aaaaatacct actatatttt tattgtaaaa tccaatagca aaccctgcta
    38641 tcactatcaa aaaagatatt aatcttgctg tacttatgtt atttgacttt ttacttaaga
    38701 gcaattcttt ttcagtacta ctttctaaaa gtttactaaa atattctatt cccataaaaa
    38761 attccaactt tcttgttata taatgaaact caaatataaa attaatctag tattattata
    38821 atctaacact gtactttaaa ttatccttat ataatatatc ttattaataa acattatata
    38881 tatacaactt gattttaatt tataaggtgt aggacataat cctaatcaat atttaattaa
    38941 atgatgtgta gttcactatt attcagtact acttagtatc gattaatttt gataattttt
    39001 tagtaaattc ttgagctgca tcgtatccca ttcctctttg tctaaaattc attgctgcta
    39061 cttctaatat catagcagta tttcttccag gtttaacagg tacaactaat ttctctacat
    39121 taacaccaag tatttcttca tattctttat ccagtcccag tctatcataa tacttagttt
    39181 catcccaagc ttctaaatga actactaaat ctatcatttt agaatttttg attgccccta
    39241 ctccatataa acttctaaca tctattattc ctattcctct tatctcaaga aaatgtctta
    39301 ttagttcagg tgactgaccc acaagcatac tttcatctaa ttttcttatt tctacagcat
    39361 catctgcaac taatctatta cccctttgaa tcaattctaa tgctgtttcc gactttccta
    39421 tactactttc accttttatc agtacaccta taccataaat atctactagc accccgtgaa
    39481 ttgttgtgtg tggtgctaac ttattatcca aatagtttga cagtctattt ataagtctag
    39541 tggtatttct atttgtgctc aaaagtattc ttttatattt tttagccttt tcaattacat
    39601 ctggcttgat ttccaagtct ctagaaatta ttaacgctgg tatttcatat gagaaaaatc
    39661 tatctagtac ttcttcccga atatgactat ccattaatcc aaaaaaatta tattctgtct
    39721 ttccaactat ttgtattctt tcatatgcaa aataatcaaa atatcctgca aactgtaatc
    39781 ctggtctatt tatatcttga gagtagacat aataatctac atcatcaggc atgtatacta
    39841 cttttaactt caactctttt attatctctc ttattgatac tttattgcta gtttccatta
    39901 attttcttcc tttctaaaaa aattataaac attatctgca atgcttttat tcattccatc
    39961 tacttctaaa agttcttcca tagtagcttt ttttatagca tctacatctt taaagtgatt
    40021 taataatgat ttctttcttt tttcacctat tccttgtata tcatctaaga tagattttgt
    40081 caaagcttta tttcttagac ttctatgata tgttattgca taattatgaa cttcttcttg
    40141 tatactagca ataaatctat ataaattagt tgttttatct agttctattt ctttttcttt
    40201 gcatatcaat cctttagttc tatgcttatc atctttgtac attccccaaa gaggtatatc
    40261 tacatcattg agttctagta ctttttttac tgcactaact tgtccttttc caccatccaa
    40321 caatatcaag tcaggtaaat ttccatgttt taatcttcta tctacaattt cagccataga
    40381 atcataatca ttaggtccaa taactgtctt tattttatat ctcctatatt ccttcttatc
    40441 ttttttagca ttcgtataca ctaccataga accaatcgaa tctacacctt gtatatttga
    40501 tatatcataa gcctctattc ttattggcaa cttttctaga tttaatattt gctttaattc
    40561 ttccaatgct ccaatacttt tttcatattt tcttttattc atatcagaaa atttttcaag
    40621 atattctaca gcatttttcc taaccatttc aactaagctt ttcttctctc ccttttgagg
    40681 aactcttatt gttacttttt gccccttttt agatgacagc cattcttcta atatagaact
    40741 atcttctatc tcatcttcta taattaattc tttaggtata tactcttgtt cattataaaa
    40801 ttgttttaca aatgaactta atatagaagc tcttggacta tccattaccc cttctaatat
    40861 aaaatgttcc ctacctacaa tcttaccatt tcttataaaa aatacctgga cacaagcttc
    40921 attatgagct cttgccattg caaccacatc ttggtttaag tcacttacag tagcatctat
    40981 tttttgtttc tgtatcatct cttcaaggct ctttatctta tccctatata cagcagcctc
    41041 ttcaaatcta aagttcatag aactctcatt cattttttcc tttaaaagtt ccatcaattt
    41101 ttcttcttta ccagataaac acattataat ctcttctatc atttttccat actcttcttt
    41161 agaaacattt cctgtacaag gtcctaaaca tttatttatg tgtagattta aacaaggtct
    41221 tgtcttattc tttattgctt tatctatatc tattttacag cttcttattg gatacgtact
    41281 acttataagc tccaaggtat cattcacagc agttatattg gtatagggcc caaaatactt
    41341 tgccttatct ttaagaactc ttctaacttt taagattctt ggataatctt cattcgtagt
    41401 tacttttata tatggataag ttttatcatc tctaagcact acattatact ttggtctgta
    41461 tctttttatt aaattacatt caagtattaa tgcctctaac tctgaatccg ttataatata
    41521 ctcaaactta tatatattct taaccataga ttttacttta gatgtatggt tttttgaaga
    41581 ttgaaaatac tgccttaccc tattttttag agatatggct tttcccacat atattatatg
    41641 gtcgtatttg tctttcatta aatatactcc gggctcagaa ggtaattttt ttaaatgctc
    41701 ttgtatatca aacatctcgc cctccaaaac attaaatttt atactaaaat tataccctaa
    41761 aatatgaatt ttaaaaagtt atacaatttc cagtgcttta aacaagttaa agcccatatt
    41821 cccttctata attgatttga aaacaatttt aaccatgaag agtaatatgg actttacttt
    41881 gtattactat ttacaactta tatttgacta atttacttat aacaaaacag tttatcgtat
    41941 atctgctcta aaatttttca caatttatat aacttaagaa aaatatttct ttaagaattg
    42001 acctgtataa gaaccatcaa ctttagatac ttcttttggt gttccagttg caactatagt
    42061 tccaccctta tctccgcctt ctggtcctaa gtctattaca taatcacaag tctttataac
    42121 atctaaatta tgttctatga ctataattgt atttcctgta tctgctagtc tttgtaatac
    42181 ttggattagc ttgtctacat ctgccatatg aagtccagta gtaggttcat ctaatatata
    42241 caaagtcttt cctgttggtc ttttactaag ttcagcagct aattttatac gttgtgcttc
    42301 tcctcctgat aattgagttg aaggctgtcc taatttaata tatgaaagtc ctacatccat
    42361 taaagtttct aattttcttt ttatatttgg tatattttcg aaaaactcaa cagcttcttc
    42421 cacattcata tctaatatat cagatatagt tttatctttg tattttactt gcaatgtttc
    42481 tctattgtat ctttcacctt tacaaatttc acaaggaaca tatacatctg gtaagaaatg
    42541 catttctatt tttattattc catcaccctt acaagcttca catctaccac cttttacatt
    42601 aaaactaaat ctaccttttt tataacctct tgctttagct tcattagtag atgcaaaaat
    42661 atctcttata aaatcaaata cacctgtata agtagcagga tttgaacgag gtgttcttcc
    42721 aataggactt tggtctatat ttataacttt atctatactt tcaattcctt ttatctcctt
    42781 atgcttacca gctctttgct taagtctatt cactttactt gcaacacctt tgtaaagtat
    42841 atcgtttatt aatgtacttt ttccagaacc tgaaacacct gttatgcatg taaacttacc
    42901 taatgggaac tttacatcaa tatttttcag attattttct gatgctttaa ctatttctat
    42961 aaaacttcca tttccttctc tagtagtctc aggaagcaat atttgttttt taccacttaa
    43021 atattgaccc gttattgagt tctcattttc aattatttca tctaaagtac cctgtgcaac
    43081 tatttcacca ccatgtatac ctgcacctgg accaatgtct ataacataat cagcttctct
    43141 cattgtgtct tcatcatgct ctacaacgat taaggtattt cctaaatctg ttagatgtct
    43201 aagagtagtt ataagcctat cattatctct ttggtgaagc cctatacttg gctcatcaag
    43261 tacatataaa actccaacca atgcagaacc tatttgagta gctaatctta tacgttgcgc
    43321 ttctcctcct gataaagttc cagcttttct tgataaattt aaataatcaa gacctacatc
    43381 tcttaagaac atagctcttc cttttatctc ttttataatc tcatgagcta taaatctctg
    43441 tttttctgta agatttatat tttccataaa gtcaatcaat tcatttacag ataagtttgt
    43501 aacttccatt atattttttc catcaactaa aacagataaa acttcctttt taagtctcat
    43561 ccctttacac tttggacatg gtctctctgc catgtattct tcaatcttat ctctcatgta
    43621 atctgaatta gtttctctat atcttctctc taagtttact attacacctt caaagtatga
    43681 tttataattt ctagttcctc caaattttga ctcataagta aactctacaa ttatattatc
    43741 tttaccataa agtaattcct ccacaaaatc atctggtaaa tctttaaacg gtgttgtcaa
    43801 agatacatta aaatgctctg ctaaactttt tatcatttta ctgtaataag tgtcatcatt
    43861 aacacctgtt gaaccccatg ctgccactgc accttgtttt attgataaat ctttgtttgg
    43921 tactactaat tctgggtcaa cttctttact ttccccaaga ccattacaaa catcacaagc
    43981 accaaaggga gcattaaatg aaaacattct tggagataat tcttctatgc caattccatg
    44041 ttctgggcat gcaaatttag ttgaaaaaag aatttcttct ccatctatta tttgggctat
    44101 tacaagacca tcagatagct taactgcagt ttcaattgaa tctgctagtc ttgattctat
    44161 tccatcttta attactattc tgtccactac aacttctata ttatgttttt gatttttatt
    44221 taagattata tcatcactaa cttcatagtt ttcaccatta actctaactc ttacaaatcc
    44281 ttcttttttg atattatcaa agactttttt atgtgtacct ttttgtcctc taacaattgg
    44341 tgaaagaatt tgtaatttcg ttctatctgg aaaatctagc attttatcaa ctatttcttg
    44401 aatagtcatc tgacttattt tttcaccaca tgtagggcaa tacacatctc ctactcttgc
    44461 aaataatagt ctcaaataat catatatttc tgttactgtt ccaaccgtag aacgtgggtt
    44521 ttttgaggta gtcttctggt caattgagat agctggtgat aaaccctcta tatattctac
    44581 atttggcttt tccatctgac ctaaaaattg tcttgcataa gcagatagac tttctacata
    44641 tcttctctgt ccttctgcat atattgtatc aaatgccaaa gaagacttcc cagaccctga
    44701 caaacctgta aaaacaataa atttatctct tggtaattct aaatctatat tttttaaatt
    44761 atgttctttt gctcctctta ttataatttt atcttccata atgttgtttt tacctttcta
    44821 tttttccaat ttttcttcta attgtttcac tttatctcta agttctgctg ctctttcaaa
    44881 ttgtaagttt tgagcagctt ccatcatctc tgattttaat ttatctatat tagctcttat
    44941 ttcgtcttta tcatctgtat cagatattcc atatacaact tcttcctctg caaccttagt
    45001 agcttctata ctatctctta tatttttctg tatagtttta ggaatgatat tgtgctcttc
    45061 attatataaa ttttgtatat ctcttcttct ctttgtttca tcaatagcat tttgcattga
    45121 gtcagttatc ctgtctgcat acataattac tcttccattt tcatttctag ctgcacgtcc
    45181 aatagtctgt attaaagctg tttcggaacg taagaaacct tctttgtctg catctaaaat
    45241 tgctataagt gaaacttctg gtatatccaa tccttctcta agtaagttta ttcctacaag
    45301 gacatcaaac ttccctaatc ttaaatctct tattatttct gttctttcta atgtaactat
    45361 atctgagtgt aaatatttaa cttttatccc tatttcttta agatagttag tcaagtcctc
    45421 actcattttt ttagttaaag tggttataag cactctttca tttttttcta tagttttagt
    45481 tatttctcct accaaatcat ctatttgatt atttataggt cttacttcta caattgggtc
    45541 taaaaggcca gttggtctta ttatctgttc tgctattgtc tctgagtgtt gaatttcata
    45601 aggccctggt gtagcactta caaacaacat ttgatttata tttccttcaa attcttgaaa
    45661 atttaatggt ctattgtcaa gtgcagaagg taatctaaaa ccattctcta taagtgatgt
    45721 ttttctagac ctgtctcctg catacatacc tcttacttgt ggtatagtga catgtgcctc
    45781 atctacaatt atcaaataat catctgggaa gaaatccatt aaagtatatg gtctttctcc
    45841 ttctgacctt cctgtaatat gtctagaata gttctctatc ccctgacaaa atcctatttc
    45901 ctttaacatt tctatatcat acttagttct ttgttcaatt ctttgtgctt ctaatagcct
    45961 atcattttcc ttgaaaaatt taatttgttc ttgaagctcg ttttctattt ctacaattgc
    46021 cttttcaatt ctttctggcg ttgttacata gtgagatgct gggaatataa caacatgatt
    46081 tctagtacca acaatcttcc ctgttacata atcaatttct gttattctat ctacctcatc
    46141 accaaaaaat tctattctta ttgctttttc atcattacta gctgggaata tttctagtat
    46201 atctcctcta actctaaagg tacctcgtgt aaagtttatg tcatttcttt cgtattgtat
    46261 ctctattaac ctttttatta catcatctct gtctctttgc atacctggtc ttatagataa
    46321 cataagttct ttatagtctt ttgggtcacc aagtccatat atacaagata cagatgatat
    46381 tattatagta tctcttctct ctaaaataga tgctgtagca gaatgtcgaa gtttatctat
    46441 ttcatcattt atgcttgcat ctttttctat ataagtgtca ctgtgagcta catatgcttc
    46501 tggttgataa taatcatagt aacttacaaa gtattcaact gcattgtctg ggaaaaattc
    46561 tttaaactca ctgtaaagtt gtgctgctag agttttatta tgagccatta ttagggtagg
    46621 tttcttaact tgttgaatga tatttgccat tgtgaatgtt tttcctgaac ccgttacacc
    46681 taataatgtc gaaaatttct catttctatt tatagaatcc actattgatt taatagcttc
    46741 tggttggtca cctgtaggtt tgaagtctga ttttatttta aaatccatag tatcactcct
    46801 tttttcgaac attagttcct gacatgtatt attatatcat acctttataa aattgtttaa
    46861 gttattttaa atattttacc catttaaatt ttacttaaat ctaaaacata aaaaaagact
    46921 tctatctttg caatagaagt ctataattca tggaaaataa atactttatt caacttacat
    46981 aataaaatca aatgcttctt tttcaactcc atctaatttt aaattaaaca tttttaatat
    47041 agttgctgca tgtgctctca ggtctccttc ttctataacc acaccacctt taatatttgg
    47101 tccaaaagct ataaatggag gtctattacc tttagtaggt aaatgaccat gtgtcgcaac
    47161 agcaaacttg taatctttta tatctgaatc ttttataata cttccttcga aatcatttcc
    47221 aaatgaaatt ccttcaagac cttcaattac catttcaaaa tcaccttcaa gaccaaggtt
    47281 agatgcttcc tctttggtaa aaatattctc tatgaataat tcttctttaa attcttcaag
    47341 cagttctctt aattctgtta acctatctaa gttatttact attatttgag ctgatattcc
    47401 agaagaattt acataggcat caaaatcctt aacttctcca ttttcaactt ttataaatcc
    47461 atttgattta agcaagacat ttggatttat aactttatca actctaagat gaccatggtc
    47521 cccaagtatt ataaaatttg tatctttgta tgtacctgca tcctttgtag cctgaataat
    47581 atctcctaac catttatcat tcatttttaa tgctttatct acttcgtcat taaataagcc
    47641 ataattgtgt cgtgtatggt ccaatgtagc taaatgtatt agcattaaat ctggtttata
    47701 ttcctttatt atatctactg aacagtttac tccaaataaa tccatgttgg gttctaattt
    47761 ccaatcgata taatgacaat gtctattgta aataccgtcc attataacct tactggaact
    47821 tcgttcaaaa gtttctcttg ggtcatcttc tctactagga gcccatattt ctgcaatatt
    47881 ataatctata tttggatttg ctcccattac aggccataat acactagagg tagttagatt
    47941 attttctttt gctacatcta taatagtttt tgcttttatg tcctttgagt accagtacca
    48001 gtctttattt tctttatttg ggtcaaattt ttcattatga tatataccat gttttttagg
    48061 atatactcct gtaaccatac tagtatgaca cggatatgtc agagtgggat aaacacaatt
    48121 tatatttttt actatggagc agttttctag tatagattta aagtttggta gattttttac
    48181 aaattccaag tctttttcaa ataaagaatc tactgataat actataacct ttgtcattta
    48241 cattacctct tcatttatat attattgaat acttttaatc aacttacaag tctatataat
    48301 tatttatttg ttttatctat tactgcttgc attgcagaag ttcctttgct tactacatct
    48361 tttggatttg catttaaatc agtaagcccc tttttaatct catccattag cttatcagtt
    48421 gcttccttgt atccatttaa cattggaagt gcaacagcat attgtaattg gtcagttgca
    48481 accttatatt gaggtttttc tttatataat gtttgtaact tttctgagtt tgttgcatct
    48541 tcagttgttg gtaagtatcc tgttgatgaa ctaaactgaa cgattttatc tgtttgtgtc
    48601 atccattcta taaattctgc acttgcttct ttttctttat ctgttccacc ttcaagcata
    48661 actagattag ctccacctgt aggagttgcg tatttttgat tttttggtaa gaatgctgtt
    48721 gatatttcaa acttaccttc tgtttgttgc ataagtcctg ctaaatctgc tgttgatgta
    48781 aatatcatac ctactttacc atttacaaaa tcttgttttg ctacgtccca ggcattataa
    48841 tcttctccag gaggcatttt cattattcca gctttcatca tatcttgcca gaacttaact
    48901 ggtgcttgtc ctgcctcatt attaaatgct acttttttac cattagttat ttctcctcca
    48961 ctttgcatta ccatagcttc atagaaccaa atatctattg gtgtttcaaa accataagta
    49021 tcttctgatt tatttgtcat tttactagca taatccttaa gctcttccca tgattttgga
    49081 cctgaagggt caagacctgc tttagttgcc atatctttat ttatgtataa tattggtgta
    49141 cttctattaa atggcatacc aacaaactta tcctcataat atgaatttgt taaaagacca
    49201 gaaaagaatc tttcttgata tgttttatca aaatatttac tcatatctac taaagcacct
    49261 gctgatgcga atgtacctgt ttgagttatt tctaataatg ttacatctgg ttggtcttta
    49321 gatgttaagg ctgcctgtag ttttgttgca ttttcatagt aatctttctg ttttaacata
    49381 tttacttgta catccttatg ttcactatta aattggtcaa ccattttttg agcagtttct
    49441 ccattagttc cacctaaagg agcccagaaa tctatcttcg taatattgct atcagtcttt
    49501 tctcctttag atgcatttgc atcattagaa tttgaacacc caactaaaga acctaataat
    49561 aatgttattg ctaatcctgt tgctaatttt cttttaagct tcattttcat cctccaaatt
    49621 tagtctttaa ttttttattt tattcctgaa tacataaaag cttcttttac ttttttattc
    49681 gcaaatatat aaacaagaat tattggtaaa attagaatta tatttcctgc cattattaca
    49741 ttccatgcag taattccttc tgaagattta aggagcgcaa ctcctattgg taaagttctt
    49801 attgcatctg tatttgtcat tactaagggc cagaaataat tattccaatg gtatataaaa
    49861 ttaaataata taaatgttat tactgctggt tttgccatag gaaccattat tctaaacatt
    49921 atttttaagt cagaagcatt atctagttta gctgcttcaa taatttcatc tgaaatctgc
    49981 ataaaattct gtctaagcag aaatatccca aatgaagatg tcataaatgg aattataagt
    50041 ggaacataag tatttataaa tccaaactta ctcatcatca tatagactgg tagaaaagtt
    50101 acttgtggtg gaatcataag tcctacaagc aaaagcccaa atagcatttt ttcaccttta
    50161 aatttaatct tagaaaatgc atatgctgct ggaaccataa ctaaaaattg tacaattaaa
    50221 acacttcctg ttacaaatac actgtttagc aaatatctaa aaaatggacc tgaatgccat
    50281 gctgtactat aattttctaa cactatatca tttggtataa tagtgggcgg taattgcatc
    50341 atttcttgtg gatttttaaa ggatgtagat agcatccata taaaagggaa tataaatatt
    50401 gcagataaaa gtaatagaat taatatttct attgattttg atgctatttt ttttatatca
    50461 actttgtctt ttttgatagg ttgtataata tccattgtct cctccttttg gataaacctt
    50521 ataatatcta ctttttcttt attgataatg aactttcttt gataagagtc taaagttagc
    50581 atatgtagca atcataacta tagctaacaa aaacatactc gctgcactcg cttgccctat
    50641 gtcatagtat ataaatccag actcatatat ataataagat aacatgttag ttgaacccac
    50701 tggcccacct tgtgtcatta tacttatctc atcaaatact tgaaaagatg cagttgttgt
    50761 tgttatcata agaaaaaata ttgttggtga taatagtggc aatgtcactt taaagaaatt
    50821 cgttattttg tttgcattat ctaatttaga tgcttcatat atatagtttg gtatggattt
    50881 aagacctgat aacactatta agatattata tccaagagtc ttccatattc ctattagaat
    50941 tagtgacatt aaagctgaac tttcacttga aagccacttt gatgttggta aatgtaatgt
    51001 cgatagtatc cagtttaaaa agccatattg tggctccata atccaaagcc acaatacagc
    51061 tacagatact agtgaaatta catgtggtgt aaagattata ctttgcgtta aattgtgtat
    51121 tatagaattt ttatttagcc aaacagcaag tactatggct agtgatatag atatagtcac
    51181 cataaaaaaa gtataaattg cagtgtttgt tatagtttgt ataaactctg gattctttaa
    51241 aagttctgta taattgttta agcctacatt ttcaaaggtt gaactaagaa gactaccaga
    51301 tttgaagctt agagatatcg tcttaattat tggatagact ataaacaata aagttcctat
    51361 aatagcaggt gttatatata aatatgcttt attaaattgc tttttcataa atatctcctt
    51421 taattttaga atacatactt ttacatactt ttacatcttc tattctttct ccatttttat
    51481 caaaataata taaatctttt tctaatacac ttattcttaa agttcttcca atatcaaata
    51541 tatcattttc tgttttgact cttatctctc tattaagaac agataaacaa tatatagttt
    51601 catttcccaa cacttcttta gttacaactt ttccaaatag actaaataca tcatcatttt
    51661 ttccatctat gtttatactc tctagtgttg ctttttctgg tctgaatcca aatttaatat
    51721 cattttttat atctagtatg ttcatacaag gactccctat aaattgagct acaaataaat
    51781 ttttaggatt ttgatatatc ttctttggag aacctatttg cattatcttt cctttgttca
    51841 ttataactat cttatctgcc attgacattg cctcaacctg gtcatgagtt acataaacaa
    51901 atgtagactt tagtttttga tgtaattgta ttaattctgt tctcatttga tttcttaatt
    51961 tagcatctaa atttgacaat ggttcatcca ttaaaaatac ctttggattt ttaaccatag
    52021 ctctagcaag tgccactctt tgtctttgac ctccagataa gttgcctggt ttcacattta
    52081 aatattctct caatcctact acatcaataa cttctgttat aagtttttct cttttttctt
    52141 tttctacttt tttgttttta agaccaaatt ctatgttttc tctaacagtc atatgtggat
    52201 ataatgcata attttgaaat accatagcta tatccctttt actagcatcc gtttttgtaa
    52261 catcattttc ttcaatcttc aacctacctg aagttatatc ttcaagacct gcaatcattc
    52321 ttaacgtagt agatttacca catccacttg ggcctaccaa tactgtaaaa gaaccatctt
    52381 ctatagtaag atttaaattt tctataactg tatttttttt attataagat tttgttacat
    52441 tttctagtct tatatctgcc atttttatcc tcccaaaata tttaatttaa ttctacgatt
    52501 tacttataga ttaataatac tcttaatttg taaaggatat attaagacaa agtgaatata
    52561 tggtaaactt attaaaataa aggttaaatt ataaacattt tttgttaaat atactgaggt
    52621 taagatgata tacagcttat gttagctata attttctata tttttcatat tcattgtttg
    52681 ctatcacaat gtaattttaa tttatgaaga gtcatataaa actatttatt ttttatataa
    52741 tttgatttga aagtaaaaaa gacctctatg ggggatagag gtctttaagt gggggagatt
    52801 gagtaattta tttttgctat attaagtttt acaattatat tatgtcccaa atttacaagg
    52861 tttaaacata aaaaataaaa attttttaat ttttataaat ttacc
//
LOCUS       DAMJVG010000017        52123 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.017, whole genome shotgun sequence.
ACCESSION   DAMJVG010000017 DAMJVG010000000
VERSION     DAMJVG010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 52123)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52123)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52123
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.017"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            78..809
                     /locus_tag="PC512_001158"
     CDS             78..809
                     /locus_tag="PC512_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HDF2440923.1"
                     /translation="MNIYAHRGFSGKYPENTILAFKKCLDMDIYGIELDVHRTKDGKI
                     VVIHDEKVDRTFNGHGFVKDFTLRKLKTLNSSFEGYQSNKECKIPTLEEVLILISPTD
                     LILNIELKTDKINYPNIEKDVLELILKYNMKNRVLISSFNSNSLKNFHKLDPSIKTGL
                     LCYLPINNVVNFAKFLGNSYLHPPLVLVNESLIELCHKNLLGVNVYTVNEEGDILHCL
                     KLNVDGIFTNYPDIASNLLHSKQYS"
     gene            889..1524
                     /locus_tag="PC512_001159"
     CDS             889..1524
                     /locus_tag="PC512_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HDF2440924.1"
                     /translation="MDNLLNELEALKSNLDNLPIEKIENYDLSKTALFIIDVNNGFAR
                     QGALYSPRVESLIKPIEMFTKKISNKLNRVIAFTDSHTPKSIELLSYPVHCLENDVES
                     ELVDELKSIENLQILPKNSTNGFFALENLDFDNIDNIIIVGDCTDICIYQFAITLKSY
                     FNQHNIEKNIVVPMNLVDTYDIPNVHPAEILNLVFFNSMIQNGVNVLKEIR"
     gene            complement(1775..2368)
                     /locus_tag="PC512_001160"
     CDS             complement(1775..2368)
                     /locus_tag="PC512_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3867 domain-containing protein"
                     /protein_id="HDF2440925.1"
                     /translation="MSDDRIIDFNELKNKVKDSDVDKFEQYIYNLYFSVMDGKMSMAE
                     FSRKIFDYMRDNNISQEKFMKIQKQFMERYGMDTEEVEKQLRNFGIDPSTAGFMSNNT
                     SSKVSTEDLESFKKSAGFYEKYGEKIQPKSCITTFIKNDLNDINVIIDQEKIMLCSDR
                     KINLMDSELNEFLLEYKNMFNKKIKVVMCETTNKYDY"
     gene            complement(2439..3302)
                     /locus_tag="PC512_001161"
     CDS             complement(2439..3302)
                     /locus_tag="PC512_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HDF2440926.1"
                     /translation="MLGIIAPSGPLRNTSLEEIKFNLESYGYEVKFSESCSLNYKGYL
                     AGNDDIRARDIEDMFLDKDVDIIMCLRGGYGTTRILDKINYDIIKQNPKPFIGFSDIT
                     GLNLAFYKNCGLLPYHGIMAANVGKWGKFTYKSLVNALEFKDELYLENPKEEKIYTVC
                     EGKAEGIIMGGNLSLIIATMGTKYEIDAKDKILFIEEIGEPQYKLDRMLTQLYSSGKL
                     EECNGIIFGDFKDCIEENDLMELLIEFANKVNKPSIYNLQSGHCIPMITIPLGRMCEL
                     DATEKIVKLKK"
     gene            3465..4634
                     /locus_tag="PC512_001162"
     CDS             3465..4634
                     /locus_tag="PC512_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2440927.1"
                     /translation="MLNIKTLCHEINDWVINIRRDLHKTPELGLEEFQTKKKIIKYLN
                     EIGINYIEYKNHTGITAYINVSPNFETVAIRADIDALPITEELNYSYKSINIGKMHAC
                     GHDAHTAILLGTCNILFKLKDYLNVNVKFFFQPAEETIGGAQLMIEDGCLEKPNVKYI
                     FGLHVNPNINKNLIELKYNTLNASTNTLQLTVHGSKCHGAYPHQGIDAIVISAHIITA
                     LQTIVSRNTNPTDSVVISLGKIEGGIKENIVCDKVVIRGTLRTLTPETREFSKKRIRE
                     ICDFTCKTFGGSISVEIEEGYPALINSNHLVDYVKQNAVELFGEENIILKDSPTLGAE
                     DFSYFLRHCEGAFYHLGCANREKNITSPLHTSTFDIDEDCLITGVMLHVKNVLSF"
     gene            4735..5211
                     /locus_tag="PC512_001163"
     CDS             4735..5211
                     /locus_tag="PC512_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HDF2440928.1"
                     /translation="MKEILINPIGKICIQGEEVFIKLDKKYVPALNELDDFSHLNVFW
                     WADGFDNPELRSILETPKPYKSGPDVIGIFATRSPIRPNPIALTAVQIINIDHENGII
                     KIPYIDANDNSPVIDLKPYTPSVDRVENPSVPKWCSHWPKSVEKSGEFNWEDEIEF"
     gene            5777..6571
                     /locus_tag="PC512_001164"
     CDS             5777..6571
                     /locus_tag="PC512_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M55 family metallopeptidase"
                     /protein_id="HDF2440929.1"
                     /translation="MKLYLSADIEGTCGIVNWDETKLECEFSQHYRTQMSKEITAACD
                     GATQSGVHEILVKDAHDSGRNINPNILPENVKILRGWTKDPLVMMAGIDESFDACIFT
                     GYHSGATCNGNPLSHTMDIDYDYFKINDEIASEFTINAYIAAYYNVPVAFLSGDEMLC
                     ESAKKLNPNIVTVPVSKGIGNGSISIHPNLALKKIEKGVKKALSGDLSRHLIKLPDKF
                     KIEIKFREHYKAFKASFYPNMKKIDSQTVLFETEDYYEFLRMLLFI"
     gene            6595..7038
                     /locus_tag="PC512_001165"
     CDS             6595..7038
                     /locus_tag="PC512_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="regulatory YrvL family protein"
                     /protein_id="HDF2440930.1"
                     /translation="MIKISNKRRIPLGEFISVFLFFAVFFGITFCIFTVIGIGFLSFL
                     GFEYKSLGAVLIFFLIYFCITTPIDFLCTTILDIFRYVNKLPYSIYKLCEFIIDFILT
                     FLAMNIIDTFMDSVTIPLSTEILFALLSYLLSECMDFFDRDKKKP"
     gene            complement(7127..8413)
                     /locus_tag="PC512_001166"
     CDS             complement(7127..8413)
                     /locus_tag="PC512_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDF2440931.1"
                     /translation="MEKVKVAVIGAGNRGTYAYAPYIYENSDVCEIVAVAEPKKGRRE
                     LFTQKYNLDSKNVFETLEDFFKHDKMADAVIIATNDDRHYDVAKLALEKGYHVLLEKP
                     MSNSLDGLVHIDDLCDKYKDKIFMICHVLRYSPFYNKLKEIVESKKLGELVSIQYNEN
                     IGYWHFAHSFTRGNWRNSNETSPLILAKSCHDMDILLYLVGSRCKKISAFGSLKHLNN
                     QNASGEMAQNCLQCLVEKKCPYSAKRIYLEKDRSINRAVHINPTEENLLNILKTSPYG
                     RCVYRCDNNVVDNMVNILQFENGVTATFNLCAFTKENGRTIKLMFSHGEVGGDLNKNE
                     IRIKEFGKNEEIVMNPSNQQNMVEEYDRNLIAEFIKLVSNKELEKGRVAAKEAIQSHV
                     MAFAAEYSRVSDEVVYIEEFFDSAKQMTKEIEETIF"
     gene            complement(8631..9521)
                     /locus_tag="PC512_001167"
     CDS             complement(8631..9521)
                     /locus_tag="PC512_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HDF2440932.1"
                     /translation="MSSTIKSNRIKGIMFIIASALGFAMMSAFVKLAGDLPSFQKVFF
                     RNLVSAIIAFWLIIKHKGSLTGKKENLKVLLYRSIFGTLGVIFNYYAIDKLMLSDANM
                     LNKMSPFLVVIFCAIALKEKINVKQIGAIIIAFIGALFIIKPTFSVEVIPYLGGIAGA
                     VFAAMAYTCLRVLGDREDYYTIVFFFSVFSLVTVGPIAFAVYEPMTLMQLIYLLLGGV
                     FASLGQFGITLAYKYAPAKEISIFDYSNIIFSAILSIFLFNVYPDMLSVVGYLIVFSA
                     AFYMFLYNKKLDKLDKEKKK"
     gene            9813..10157
                     /locus_tag="PC512_001168"
     CDS             9813..10157
                     /locus_tag="PC512_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HDF2440933.1"
                     /translation="MEIKRYEGTGRMSRAVVHNNTVYLCGQTHAEGGVIEQTTEVLAK
                     IEDLLNKYGSDKQHLLSVTIYLRDMKDFEAMNSVWDAWVEKGFEPARACVEARLAREH
                     LLVEMSVVAATK"
     gene            complement(10316..12412)
                     /locus_tag="PC512_001169"
     CDS             complement(10316..12412)
                     /locus_tag="PC512_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CocE/NonD family hydrolase"
                     /protein_id="HDF2440934.1"
                     /translation="MIKFKLYISGLYSGNVIFDGDLLIEKLNPFTNKIESLKPISKEE
                     NTYYLNLTKIDLKSLFNNFDVYTKSLVNTDKDTVINNLGETHSKLNEYIWVQRNKKFP
                     LDIIIVDNKIVGFICLSRETCTILIMDGYEEYTVLKEWEKTHKNEEIYSIRFGGNYMI
                     DMKDGIKLSTDVYLPDFVDSAKKAPTILMRTPYGKENDKEIYYKYVQRGYAVVIQDVR
                     GRNESEGKWEPMIHEREDGDSTINWIVSQEWSSGIVGMLGASYLGYVQWAAASSGNKH
                     LKALVSIVTSGSPFIDIPRKGGAFVSGMLAWAFMVSRNKVDRSKMVRDDWDDVLNIRP
                     IENIPVEALGYRIEFLEEWLKRVEKDEYWDLMDWHLQKDKINVPALVVSGWYDDNSMG
                     TTEALDVIKDYEKGKRKAILGPWMHNSNTLRDINGISLGNSSLRYDLDYNYLLWFDKY
                     LKGIENNIDTTAPVEYYSVGSNKWKTEENWPIINKIDKSMYLISDGNANTSLGNGRLV
                     FDNDLEEKYDSYIYNPKDPSVQLIDMSENEVGVPNNYKDLEKRSDMLCYTSDAFSEEF
                     TVTGDIKLEFFASSSAKDTDWVIKIMDVDLDGNSIKLADGILSARFRNSFYKSEFMEE
                     GEIYKFTIITSKISNTFKVGHKIRLDITSSAKNFIFQNSNTTEGYNSIEYIEAKNTIY
                     HGGKYPSKLILPIENK"
     gene            complement(12425..13585)
                     /locus_tag="PC512_001170"
     CDS             complement(12425..13585)
                     /locus_tag="PC512_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 family protein"
                     /protein_id="HDF2440935.1"
                     /translation="MNTLFSNPGSILAVMTSMIALGFYLQRYKAIKSLGPALTIIIMG
                     IILSNLKVVPVSTELYGTISTYAIPISMTIMLMSVDLKEMTKLSREPLIAIFVAVLTV
                     SIMAFLFGLVFAEKISEGWKVAGMFVGTYTGGSANLTAIGTGLNVSRQTLAAANAADY
                     VIGVPTLIFMFALPAILKNSKKFKKLWPYHVEESELEDCQNEEFMESKEWSIKDIAWM
                     LAIGFVVTEVSTILAGYFNSSFSSAARILLVTTISIIIAQLKPVKKLKGNLDLGLFVA
                     LFFLCTIGFSVDIKEFLGSTFTITLYCFSIIFASFVFHLGITRLLKIKYQYVILSIVG
                     AIADGPTSALVAASAKWNSLVSVAVVMGVIGGVLGNYAGISVAYAIKMSLGL"
     gene            complement(13604..14671)
                     /locus_tag="PC512_001171"
     CDS             complement(13604..14671)
                     /locus_tag="PC512_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide epimerase"
                     /protein_id="HDF2440936.1"
                     /translation="MKITDIKFEKLRIKLKKPVVVSFGVIEYGESIILKIETDEGYCG
                     FGEAAPLAAVTGEVLDNVLSVLLMFKKELIGKDPLDIETIHTIMDGIIIGNTSAKAAI
                     DIALYDIKGKIMNAPLYKVLGGFDSKVQTDITISIDKPEKMAVEALERVKEGFRILKL
                     KAGINPEDDIEAVKLIREAVGESIRIRIDANQGWNVNSSINTIKKLEEFNVDAIEQAL
                     PHWDLDGTAYIRNKSNTKIMIDESLHSPIDAIKAIKKNAVDTFNIKLMKSSGIYPAIK
                     INNIAEASGVNCMLGCMLETRIGITAAANLIASKKNITEADLDSFMFCEELEGISGGF
                     VMDGDIMNLVNKPGLGIEVNL"
     gene            15023..15589
                     /locus_tag="PC512_001172"
     CDS             15023..15589
                     /locus_tag="PC512_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2440937.1"
                     /translation="MLGEKMRNIRKSKKKTLSDVSKLTDLSISYISQIERDAIEPSLS
                     SLRKIAEVLDTPLYMFMDDNNTDDLVIRKEDRVMMKFPKSEMFYEIVSPMPTTEFTPS
                     ILFVEFELKPESEDAKDYIYHASEEIMVVTSGVVDICMGEKVVRLNPGDSTFIKANVP
                     HKIINPSKDTIARGYGVISPPIWPIKSK"
     gene            complement(15784..16770)
                     /locus_tag="PC512_001173"
     CDS             complement(15784..16770)
                     /locus_tag="PC512_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-dependent carboxyltransferase"
                     /protein_id="HDF2440938.1"
                     /translation="MGFKVELGGFQTLIQDRGRVGYGQYGVSGCGAMDEYAHRVGNIL
                     VGNSEDEASLEVLMLGPTITFDEYTQIAVTGGDLGAKINGKEIQNWRSYQINPGDVLS
                     FRGVKSGARAYVSIAGGIDVPLAMGSKSTYTRAKIGGFEGRALKKGDYINTFIQEKDF
                     TINKKLSSKYIPTYSSEIVLRIVKGPQFDAFSNGEVEKFLSNKYKVTNEIDRMGCRLD
                     GESIKHLNGADIISDGISYGAIQVPGHGKPIIMLSDRQTSGGYTKIGNVISVDLYKLA
                     QAKPNDVVKFELVDIYEAHRLLREQEDKIQDIYKSMKNIRVVKAKVLNDIAV"
     gene            complement(16800..17495)
                     /gene="pxpB"
                     /locus_tag="PC512_001174"
     CDS             complement(16800..17495)
                     /gene="pxpB"
                     /locus_tag="PC512_001174"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpB"
                     /protein_id="HDF2440939.1"
                     /translation="METRYLISGDKAVVAEFGNEISEDINKKVISFMRAIEISNLKGI
                     VTEMVPTYRSLMISYNPLEIDFDSLIENLKKIEDNLESIVLPKPKIHEIPVCYDEVFG
                     IDIKNVASYNNLTVDEVIKIHTSREYLIYMLGFTPGFPYLGGMDERIATPRLEVPRTK
                     IYGGSVGIAGSQTGVYPIDSPGGWQIIGRTPLKLYDENREEQILLRAGDFIKFVPITL
                     DEFIEIEKNNLSI"
     gene            complement(17515..18735)
                     /locus_tag="PC512_001175"
     CDS             complement(17515..18735)
                     /locus_tag="PC512_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HDF2440940.1"
                     /translation="MSTKNITDKTKNKKDVGALIGAAFIMATSAIGPGFLTQTAQFTQ
                     DFGPNFSFVILITTILFIGAQVNVWRVIGVSGLRGQDIANKIIPGLGYLVAFLVALGG
                     LAFNIGNVGGAALGMNVMFNMNMTLGTVLSGLIAIFVFMSKNSNSLVDKITKFLALGM
                     IIIVGYVAISNHPPVGEAVSRMVKPENPKGLIFPIITLLGGSVGGYITFAGGHRLIDG
                     GITGEENIKEITKSSLLGILVATMMRVLLFLAILAVVSKGLQLDPENPAASAFKFSAG
                     AIGYKFFGLVLWSAAITSVIGAAYTSVSFLKTLNPFIDKYEKYFIIAFIAISTLIMAF
                     IGKPATLLILAGALNGLILPITLGIMLIASKRKDIVGDYKHPTWLLIFGLIVVLISAY
                     TGITSLSSLGALFA"
     gene            complement(18764..19555)
                     /locus_tag="PC512_001176"
     CDS             complement(18764..19555)
                     /locus_tag="PC512_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LamB/YcsF family protein"
                     /protein_id="HDF2440941.1"
                     /translation="MYKVDLNSDLGESFGTYKIGLDEEVLKYISSANIACGFHAGDPS
                     HMEKTVQLAKKNGVKIGAHPGFLDLIGFGRREMKITKQEAKDYTKYQLGALMAFASSN
                     GCNIQHVKPHGALYNMAAKDKELAMGICEAIYEVDKDIILLGLYNSEMINSAKEIGLR
                     FANEVFADRAYDNNGFLVPRNVEGAVIHDTKHAIDRVVRMVKEGTVETLTGEVIHIKA
                     DSICVHGDNPKAIEFVKEIRKRFELESIEVCPLENIEVCSSENIV"
     gene            20143..20772
                     /locus_tag="PC512_001177"
     CDS             20143..20772
                     /locus_tag="PC512_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2440942.1"
                     /translation="MDKNYTMPIYQKIALDIANKIYTGEIQEDSVLFGRSVLAGKYNV
                     SPETIRRSVKILEDIGVVKSIKGKGVIVLSPDKASSFIKKYRDITNISSYKSTLYNLI
                     DTKSNLENEILDTINKILDYSNRLEIINPLVPVQFTINSNCKYIGQTAAQTKFWQNTG
                     ATIVAIKRGEELIISPGPYIEFLEGDILLVVGDQHIYNSIPMFLYENEK"
     gene            complement(20886..22400)
                     /gene="glpK"
                     /locus_tag="PC512_001178"
     CDS             complement(20886..22400)
                     /gene="glpK"
                     /locus_tag="PC512_001178"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HDF2440943.1"
                     /translation="MEKKYVMALDQGTTSSRAILFNKKGEIVKIAQKEFNQIYPKAGW
                     VEHDPMEIWGSQSGVMREVIETAGIRPEEIASIGITNQRETTVVWSRYTGKPIYNAIV
                     WQCRRTSEICDELKNKGLEESIKEKTGLLIDAYFSATKVKWILDNVEGAREKAEQGEL
                     LFGTIDTWLIWNLTRGKVHVTDYSNASRTMMYNINDLEWDEDILRELDIPISMLPLVK
                     PSSYVYGHTDERMLSGAKIPIAGCAGDQQAALFGQNCVEEGTAKNTYGTGCFLLMNTG
                     SNIVKSKHGLLTTIAWGVDGKVTYALEGSIFIGGASVQWLRDELKIIESAKDSEMYAN
                     RVEDTNGVYVVPAFTGLGAPYWDMYARGSILGLTRGAKKEHIVRATLESIAYQTKDVL
                     EAMQNDSKLKLKSLKVDGGASNNNFLMQFQSDILNVDIDRPKIVETTALGAAYLAGLS
                     VGFYIGRNEITSKWSVEKEFNPNMSEEKRCKLYKGWKKAVSRALSWEKEDELDI"
     gene            22644..23186
                     /locus_tag="PC512_001179"
     CDS             22644..23186
                     /locus_tag="PC512_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2440944.1"
                     /translation="MPKILENVKEDILKVSRDMILEEDYSNISIRKIAQRCGISAGTV
                     YNYFNSKQEIIEYITKSEWDLLIRRIEYSNKNTEDYIKKLNIIFTEIRNFINKVHNIQ
                     YNDFLNTFETERFFEMKKHKDDFHEQLSNKVYEALEKESFFNNDKLVCNIIIKMFFSY
                     STYLHIEFEDLKPYIEKLIH"
     gene            23200..25692
                     /locus_tag="PC512_001180"
     CDS             23200..25692
                     /locus_tag="PC512_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2440945.1"
                     /translation="MNHNTSIKNKDSNPKIFLVLTLYLLGIFMGAIDTGIVSPARTII
                     QNSLGVNEKTGIWMITIYTLTYASVIPISGKLADKIGRKYVYLVSIFLFGSGSLICGL
                     SSLFSNFYILLIGRVIQAIGGGGIMPIATAEFGTTFPENKRGMALGLVGATYGIANIL
                     GSSIGSTILSIFGTQNWKWLFFVNLPICLIILIGGVFCIKNNKSESKEKIDKLGTLML
                     ICIIVSLLYGLMNIDFFNFKNSIQDISVYPYLLTFIVLIPIFIFIENRAKDPILSFEY
                     FLNPRILIVLILSLIVGIGMMGMVFVPQYAENALKINAGSGGYFVAILGLFAGIAAPL
                     SGRLIDKFGAKKILLLGFSVSMIGSLYLVLIALKTNTVFSVCVSLIFMGLGMGFTMGT
                     PLNYMMLSNTRLEESNSALATLSLIRSIGTSISPAIMIGFIAHAGLSVQDNIMDLVGK
                     PSTPKIVQLEELENMIDDLKSDPEMAKNLKNVSIPNMNDTSNINMDMTGGKLPKSLLN
                     KVQSADTTNITNITKEISTTMFDEKVPSIITKIQKNVQKGIDGTQSGINGIEDGENKL
                     NSGIKGVQTGIDNMVKARAGINQGIDGVKKGIAGVDKGIKGMEQGLEKQDEAIKELTT
                     AYNKIPTTEKTPTDNENNSNEQNQSNTSNSESDDTKNDSTENKNNNSSENKPNVNEQK
                     ESLNAQIQQLKKTRDDLNTKLQKNKTQKNELSKKLRSMESQKKELQSKLNNSISQKKD
                     MEKSLDTMQQQKKSLQAVLAKTQEVKTEIPKAFDKSKLDYINSIENNRTKIENTLQST
                     LNSGFKQMYITVFCVNLLAFIILLFYKENKTR"
     gene            26113..26511
                     /locus_tag="PC512_001181"
     CDS             26113..26511
                     /locus_tag="PC512_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2440946.1"
                     /translation="MDTLGKRIAYLRNSKKLTQRKLMDILKFENLGKYETGDRKPNCD
                     ILMSIADYFNVTTDWLLYGKEKVNVNSSVKEDKEDYLHVTNDEMTILNLYRQLNERDK
                     IKIEGILELKISEYKDLKKHSSNNNEDKMV"
     gene            complement(26728..26937)
                     /locus_tag="PC512_001182"
     CDS             complement(26728..26937)
                     /locus_tag="PC512_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440947.1"
                     /translation="MCKLDSDGVIECCRAIDDFITALSNIKSLNMERLNTLTKYSSTC
                     SILLKEGNYEGCTIVYRKMLEELKT"
     gene            complement(26969..27178)
                     /locus_tag="PC512_001183"
     CDS             complement(26969..27178)
                     /locus_tag="PC512_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2440948.1"
                     /translation="MDARKKWIPFLGVQVKQRLIELNMTQRELAKKIGVNENYLSAIL
                     NGRRTGKKYKSSIYQLLNIEYSEDD"
     gene            27477..27896
                     /locus_tag="PC512_001184"
     CDS             27477..27896
                     /locus_tag="PC512_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2440949.1"
                     /translation="MDTLGERIVYLRKAKNLKQYELEEMLGCDNLSKFERNIRKPNYE
                     ILKSIAEIFNVSVDWLLNGDNLSHKSDLICDSSSNYPLNSINSNEIKLLNNFRKLNDY
                     DKAKIEGMIELKLHEYEKEKDLGKIEYNKNKDEKIDK"
     gene            28124..28579
                     /locus_tag="PC512_001185"
     CDS             28124..28579
                     /locus_tag="PC512_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440950.1"
                     /translation="MGLRDKFAQSFARSKTMSGPEKKANEIMGKLLLKKAILPIVLMF
                     VIIIAGAMLKINSWVTLGINLVIAVGAFFYIRNSSKKYQNFKPYVGNLISLEKKGKKE
                     YVAIIKQGKLPVKLQIAYGGEDLEHVKKNQMVQISYNPDAKIAILVNRQ"
     gene            complement(28786..29046)
                     /locus_tag="PC512_001186"
     CDS             complement(28786..29046)
                     /locus_tag="PC512_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440951.1"
                     /translation="MDKLITELSSLGAIGILCALLFKNTMQEKKEDRDMYKKTVENFI
                     ELSTQQQEINKNILVQMGIMKTDVEEIKEDVTDIKGMLQNGV"
     gene            complement(29309..29662)
                     /locus_tag="PC512_001187"
     CDS             complement(29309..29662)
                     /locus_tag="PC512_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440952.1"
                     /translation="MFKFDKNKIEQIKQGRKVEMQYKDISDISIGQVKQDDDITNNFI
                     ANVEIYEMLLNQSSVNEASNISTFSVRKSGGESGMVEVYVALILRGKKTIEEVPAVIR
                     EQVRIRCKELEIPVE"
     gene            complement(29679..35000)
                     /locus_tag="PC512_001188"
     CDS             complement(29679..35000)
                     /locus_tag="PC512_001188"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012632.1,HMM:NF024930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440953.1"
                     /translation="MKRTKLLQRGNFFGDKNMVVDEFDEGYDNYDFINFFTGCCNYTF
                     GLKNNNILYGCGDNSNFQLGLGEDNTTRKLFTKIPNISTNIKKVACGESHAVILTSDG
                     ELLVAGINTDGQMGLGLEKVGKTVSTFEKVPEIKGVKDIACGLQSTYLLYNDGTLYVA
                     GNNLYGQLGLGTNGASANVNTFTKVDVDNVKAVFSYNKSAFIIKNDNKCYSTGFNNQG
                     QLGLGDKNNRDLFSLVSINDVKTIACGSEHTVLMTYNNDIYGCGKEKCFGNALQSSLF
                     TKIEEVNIKTIACGHGNTMLIDNKGTLKVAGNNDIYQLGIANYSENIDNSFIDLKNIV
                     AKNIFIGLSHSILIDSNNDSYCTGDNTYGQLGSFFDDMHIVEFKKMDSEKYSYSNYIN
                     LIKSEDKLTLLKEEMEIKDIELPLDIHSVRDVVFSPYCTLVILGNGDVYGLGNNRYKG
                     MGSDLPSQLNELTKLSISNVKSIVASKNISGGIFYIKNDDTCYYSGPNSNSIAGVLPS
                     NSDVFKKISIDNVKKVVINTDLSNWFSLIVTNNKQIYTSGKSSSYVNGLSNALISQYT
                     EISLSNVTDAYSSYNATFIVVDEKKVYATGINTNYLLGFSTSDGSNVNLGLLSDWYYI
                     NISGSSYSRVSCTNNITKINNIIIYEYVTVFCTNIGSFLTGYHGTSWTKPTDSSYRVQ
                     YQGISYAGYLDSYIYNYYPTRCTQSSSSTTFAYLYNGESSSNLKNVNPDNLLISGGSS
                     YIHQYGRNYLNNQSSNNIAASNINSGPITSDKAIFLYKALLYLSSNTLYGFGNISESA
                     KELDVSDTQDGYNATNYKKVMKNIKNIFIPPYDLSRDKTRFAILTDKSLFICGYNSKG
                     THGISVNSSLNLNNKINYNKKNSSSEISSNIQEIYSHSKSTYLLTNNNMLYSVGLNDV
                     GQLGVGDEINRKVFTKINIDNIKSINVNRFTDNSKHAFAIKNDNTCYAVGLNNSGQLG
                     IGDNVNRNIFTKINVENVKYVAVYGNTSLLLTNDGLLYGAGNNGKGQLGLGDTTSRNI
                     FTRIPINGVRDVYLCNDVSIIVKNDNTCYVCGLVNGYFGFTEGSISTFTKINIENVKS
                     VVTAGSEATFFITNDNMIYTTGKKERVFFSTETNDIKGIRVINNIINAKKIVVNGYTS
                     AILTNDNKLFVGGLSGYGSIANNNNTNSVEDVKDVFVTANNTLYIDNNNNLISSGRDT
                     YGISDESYRDMSVPYYKVSIKKDVDTVFSSYNTIFIKDIYGKFYSSTGDNRYNHLGIH
                     HRYDNDKNEALEGSLHSYFKTDNTSDKIVFNKKNEKLVMFNDKYIKTNNKYINYKNIF
                     KDNFKYTSIILPFEVSDIDISKTHSLAVAKDGKLYGIGSNSYKEINQTLEDIELLTLT
                     EVNISDVKKVACGDNYSYIIKTDNTLWSYGKNTEYQLGVGHNNDVRELQKVTGLPSVK
                     DISIYNSMTLVLTNEGELYAQGYNTNGLFGLGESEKDKIIRTFTKVLTNVKEIKSHND
                     DHILVIKNDNSLWITGKNKSMYKISISITDLYEFTKIPIPEHLNDILDIELSDDTIYM
                     ITKVDTSKASIEIVEKSISQVRVVVQDPNNVIEKLEMFINDELISTKTNLEINSIIFE
                     IPQNKIVLGENKILIKASSPTGDLYSSMFIFKSETGLKVKKDSILMINNKVYSIINIT
                     ENNTDLIVTLNEGLKDDMMENNPIYQLINKTKVQVKINKSDLFKDMKLVEIKKSDSSY
                     QEIYELEEANIKSAQPKIIVEKGDKWTAIKRPSMIFRYDAENNEPQA"
     gene            complement(35017..36000)
                     /locus_tag="PC512_001189"
     CDS             complement(35017..36000)
                     /locus_tag="PC512_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDF2440954.1"
                     /translation="MEEKFYIILTKIGREKIANATALGELVGLTKFQVGDSNGEYYEP
                     TEEQTALKNVVWEGNINSLRIDEKNPNWIVIETILPGTVGGFMIREAAVLDNENNIIA
                     IGKYPETYKPRAEDGSIKDLVVKMILQLSNTSNVTLEVDPTLVFVTQKDIQDLDDKFD
                     KNIKEIKVKIGEELLSTEAKNLSGAINEVVEKIKNISIDDVIGGQIQTELSVLKNSYN
                     KLSEKVLDILIYLELESEIDVDEAGYWYDTLTNAKNIIAIEGLKLDLNRKCITGELGS
                     VTFKNVVLPFNANRVRYIHEMDNNFVETKSNRAYSIGQTDITLNKYSYEIR"
     gene            complement(36001..36699)
                     /locus_tag="PC512_001190"
     CDS             complement(36001..36699)
                     /locus_tag="PC512_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2313 domain-containing protein"
                     /protein_id="HDF2440955.1"
                     /translation="MKLIDKLPSFDRNYIVEEIQGAYDTELNILKEDIDDTFNQLFVD
                     TATWGLDMWEDILCIEKKELDFDTRRSNIKAKMRSRGTSTIEVIKSICEAYTKSETDI
                     KVYSDEFTFVLSFIANNCDYKTLLDCSDMIERVKPAHLLHYLEPIILDKSMVYCGGGM
                     VCSEEVKVHPYFEPIIKCSAVVNCGAGMISREEIKVYPLSIKCIENNCKINIAIANDT
                     GVENVVVYPKSEVV"
     gene            complement(36696..37748)
                     /locus_tag="PC512_001191"
     CDS             complement(36696..37748)
                     /locus_tag="PC512_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HDF2440956.1"
                     /translation="MYSDQTYEVIKNRTLENINLDIYKGEGSFLNNMVSGNNLELSKI
                     YLELSKMHKMAFIQDTYNQFLDKRVNEFGVYRKLGTESNGEVEFIGEKGTVINNGTII
                     SYRDLLFVVIKDVTIGSEEGDNSPVQALEVGKKYNLPTNCEFKLVDNISGVTKITNTR
                     SFEGGTDIETDEELKERFYKIQRNQATSGNKAHYEEWALEVDGVYNVKVYPRWDGPGT
                     VKVLIFGKNNQAVDTETIERCQQHIDEEKPIGPTITVVTPLPIEISISAVMKLEDGYT
                     LDNVKESFLESINTYFRDIRGEIIYTKVMGILINTTGVHDLSNLLINGSTDNITINED
                     KIPSVTTVNFSEVENQ"
     gene            complement(37741..38169)
                     /locus_tag="PC512_001192"
     CDS             complement(37741..38169)
                     /locus_tag="PC512_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HDF2440957.1"
                     /translation="MSTIFPFIGVPEDYILPKTEELPIFREVAWDFEKDEPILEKGDF
                     KIIEKKEALKVWIYKCIKTNRYEHEIYSLEYGTELSELIGQKYTKGLTESEASRFIKE
                     ALLINPYILEVNVKSANFNRDILSANVKVSTIYGEVEINV"
     gene            complement(38169..38495)
                     /locus_tag="PC512_001193"
     CDS             complement(38169..38495)
                     /locus_tag="PC512_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 family protein"
                     /protein_id="HDF2440958.1"
                     /translation="MANPINEFIGIIREEGKYHNQPSFFIGKIKSKLPDLKIETNNII
                     LEKEDILIDSWMIDRQLETFDTETNQEHQHEVKNPFIDNFESGDMVIMFRIGEKFAVV
                     SKLVSL"
     gene            complement(38511..40040)
                     /locus_tag="PC512_001194"
     CDS             complement(38511..40040)
                     /locus_tag="PC512_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HDF2440959.1"
                     /translation="MIINRSKDSSSNEISFVSKDMGFLLTQSEVSYNFKDKLVEDIAK
                     QVFAENRLSVGIIAKTNVKYTKMFIGVNGYDTIMSAYTEASKKTKKKYMIEANLDKFN
                     VIEKGTVTLSVMFEEGFNIINTTFSESMENVKNKVIVVDQYGSKISEKIDNEIFKEVN
                     VIMQKVIQQQENQDVDIDSEFNGIEKSCSLKGYGDVSCITGRGVKVKDSYTKLVGLFY
                     IDTDKHTWQNGEYQIELELNFQNLMDEKSAGQDEPKEESNLGGEDYAGGKEFTAEFTA
                     YCPRKEEGGDTDCRKKKLDPSKKTCAAPMVGKYEQTYYTKEFLNKHPLLNYGDEIQVI
                     TGVSGRDGVYKVNDVGPAITIEKNGTYHIDILFGNVEEASKFGRRKGKIIIGGYSGNV
                     SDKAKIVISEAKKHLGKPYKWGGNGPSSFDCSGLMVYCFKKVNVSLPRTSNQQSKKGK
                     KVEQKNLQAGDLVFFHNPVSHVGLYIGNGEFLHAPQKGDVVKISKLSSRRDFNTARRV
                     L"
     gene            complement(40322..40744)
                     /locus_tag="PC512_001195"
     CDS             complement(40322..40744)
                     /locus_tag="PC512_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440960.1"
                     /translation="MEMWLRQAEDRFRFPVFPSSFSINGKAAVNSSSILKIGEIATFG
                     GVALKSISISSFFPNKDYTFCDYTGFPSPYDCVNKIEKWMKEGFILRFTITETNINME
                     VIIEGFSYEERDGTRDVYFTLDLKEYKRIKIPKVTPKQ"
     gene            complement(40744..43197)
                     /locus_tag="PC512_001196"
     CDS             complement(40744..43197)
                     /locus_tag="PC512_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440961.1"
                     /translation="MGNVREEGINMYLTDNYTPKMNQIISVTDNFRRATVAVSLSTNV
                     MASSIKNSIGSASNRVNSLNSSLRKVQTTASSVSSTMTKLSSSINAVSGVIGSLNGSI
                     MRLAITIAMIIDYFNKLIQKKNEFNSNIMIILIFKAKSDEVEKTKNKLLGNLKKIGGK
                     IWNIVIKAKDMTKRVISSILGKLKQVEKRPYQGSINLKDMVSSAMGRILPKLMLFKNT
                     FWSGVIAIKDMASGIISKVFPKLRLFAGKVWSGAIAVKDMASGILGSIKGKISDLTNG
                     ATIGVAVKKGVDLLGQEQNQKVVLESVMKRNTGKVNQIDVDDYYGSLVRMANDTPFDP
                     EDVVAMGTKAKMISNITGGKKEKDITQAMVDVRALNMNTSSEQDVSAAFLSAAKGNME
                     SLNTLVGENYKTFDEALEGISVKQMGLAKEMSNTIPGIISGAQTSINNGLKSIVKPFD
                     DILGQGLKKIKTFIESGLGNLAGLSEKMAGKIGNVMNGKIIIGNKYDQMQSRSVKNGK
                     EFSDSTQYRISNEAEKRKMMVENKQERFENHAATMIGNAPKAIVNAGSTLLQNIDFTA
                     LIDSLLPVVNLVNNLLDSINNKSPIAQGLISIFGTIVTTAFQLIGPVVEAVSPIITRI
                     FTFLGEYAPQINNFIETLGVIWKTVWETLGPLLETGWKIIEPILGAFFNILDKVCKIV
                     KDICKWWQTMINKIKNGSITGTVLNLVEKSKKNYKDNPYAGTKAGDSGKAYSGKKGNN
                     AFGLNYVPYNDYQTRLHEGEMVLTKQEANQYRSRKNGGNINIAKLADTIVIREEADIE
                     KITSKLVASIQLAQLGGVL"
     gene            complement(43197..43364)
                     /locus_tag="PC512_001197"
     CDS             complement(43197..43364)
                     /locus_tag="PC512_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440962.1"
                     /translation="MYYYWKKKGIRPSLFYAMDKGELKLIEAFFALEIEEEVEKMKHG
                     YGVCPLTGGGM"
     gene            complement(43391..43837)
                     /locus_tag="PC512_001198"
     CDS             complement(43391..43837)
                     /locus_tag="PC512_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDF2440963.1"
                     /translation="MSENGLSKNINIVDLLLNSDTENLERPSTIVELKRLSTIFGQEF
                     KVMCRALTISKDEEIQNTCLKIDENMKTDIDLPEMQMLTIIEGVCDLDGKLLFKNKEL
                     MDKFKAPTPKELARKLLLPGEITNLYRILQDVMGYGKNAVIEEVKN"
     gene            complement(43951..44379)
                     /locus_tag="PC512_001199"
     CDS             complement(43951..44379)
                     /locus_tag="PC512_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HDF2440964.1"
                     /translation="MANMEARNVMSGTWGELWLDGNKVAEVKKFQAKMEFTKEDIIIA
                     GQMGTDTKYMGYKGKGSITLYHVSSRMHKLIGEKIKRGSEPRFVAISKLNDPDSYGAE
                     RIAVKNIAFDDLTLADWEVGVKGEIEAPFTFTEYDFLDII"
     gene            complement(44393..45457)
                     /locus_tag="PC512_001200"
     CDS             complement(44393..45457)
                     /locus_tag="PC512_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath subtilisin-like
                     domain-containing protein"
                     /protein_id="HDF2440965.1"
                     /translation="MAIGLPSINISFKELATTVKERSARGIIAMVLKDAKALGLNEIH
                     EKEDIPVDLSAENKEYINLALMGNVNTPNKLLVYVIEGEADIQTALDFLETKEFNYLC
                     MPKAVEADKTAIKNWIIKLRDIDKVKVKAVLGKVVGNHEGIINFTTEDVLVGEKKYSV
                     DEFTSRVAGLIAGTPLSQSVTYTKLSDVVDIPKMTKVDAESRVNKGELILIKEAGAIR
                     IARGVNSLTELTAEKGEMFQKIKIVDTLDIIHSDIRKVIIDDYIGKVTNSYDNKCLLI
                     VAIKSYLEELEKSALIESDSTVEIDFEAQKSYLKSKGVDLSYMTLQEIKEANTGSKVF
                     LKAKIKVLDAMEDIDLSIEI"
     gene            complement(45462..45905)
                     /locus_tag="PC512_001201"
     CDS             complement(45462..45905)
                     /locus_tag="PC512_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440966.1"
                     /translation="MLKYKEILETIIEILKKNFTESIFIDDESVQGSEGSCFFVSILS
                     VICTPVMLNTNNKDIVISIKYLPKPQSKSIRMYEISDELNKLFNRNIKVTDRKLNITK
                     LEQSIKKEESIYVLNFTFTLNYLDSVYEEDVVYENMKEINLNLGE"
     gene            complement(46154..46594)
                     /locus_tag="PC512_001202"
     CDS             complement(46154..46594)
                     /locus_tag="PC512_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440967.1"
                     /translation="MENKKDILFKETDKRLHNYKYLDIKIKNINLDIKRCENEYSGCG
                     AMVYTEKTSNTYNISSSVENEVLKREERLRKLKMEKEDIEIEKEKIENALTCLNDIEM
                     EFFNLFYNSKTKNNMTYISMKLHLDRTSCYNLKKKMIFKLSEIL"
     gene            complement(46699..46896)
                     /locus_tag="PC512_001203"
     CDS             complement(46699..46896)
                     /locus_tag="PC512_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2440968.1"
                     /translation="MFKNNLKYYRKCKGMTQIQLARKAGITNDYISQIERGIKNPGLL
                     MAKKISSILEQNIEEVFFIQL"
     gene            47065..47385
                     /locus_tag="PC512_001204"
     CDS             47065..47385
                     /locus_tag="PC512_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HDF2440969.1"
                     /translation="MFAKRLRELRKEFGLTQRELGEKVGVSQRVLGYYETENRFPDEH
                     ILNKLADVFNVSVDYLLGRTLVKENIDTVAAHRKNPHEELPEEAQEQLNDYIEFLLNK
                     YKKK"
     gene            47467..47973
                     /locus_tag="PC512_001205"
     CDS             47467..47973
                     /locus_tag="PC512_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440970.1"
                     /translation="MNNLDKLFELASQEEIIIHYTTYIAGDLEGLYINKHGIKIISLL
                     SNLKQNSKKLTSILAEELGHHFTSLGYYVSSYNDYYTKIIIDKCENKALKWACEFLIT
                     EEDIINIINSGITCVYEMADILNVDITFFQKRLEFLSLKKQSLQLGNNKYLILTNLPY
                     FYIFDPIS"
     gene            48674..49429
                     /locus_tag="PC512_001206"
     CDS             48674..49429
                     /locus_tag="PC512_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDF2440971.1"
                     /translation="MEKKVLATVGEKEITNIDIENALKSLDPYQAMQFKTEEGKKHLL
                     NDLVNQELFFLDAKEEKLDEEEIFKLEMKKIEENVLKQFAINKVLSSVNVTEDEKVKF
                     FEANKSSFSKPESATAKHILVDSDEKAKEILAQIKSEEISFEDAALKHSSCPSKDMGG
                     DLGTFGRGQMVPEFEEAVFSMAKGEVSEPVKTQFGYHIIKLEDLQESTESTFDEVKAE
                     VEKSLLYQKQNEVYGNKINALNAKYGNLVKYND"
     gene            complement(49572..50000)
                     /locus_tag="PC512_001207"
     CDS             complement(49572..50000)
                     /locus_tag="PC512_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HDF2440972.1"
                     /translation="MNILFFLTPKSEVAYIYEDYTIRQALEKMEYHKYSAIPIISKDG
                     KYVGTITEGDFLWTLKNDLNLDLKGLEDVPVTDINRKMDNSPVSINADIEDLVIKSLN
                     QNFIPVIDDQDTFIGIIKRRDVIGYCYEIIRGYKNLANDN"
     gene            complement(50421..50621)
                     /locus_tag="PC512_001208"
     CDS             complement(50421..50621)
                     /locus_tag="PC512_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDF2440973.1"
                     /translation="MKTGVVKWFNNEKGFGFISVEGEGDVFVHFSAITGDGYKTLEEG
                     QSVEFEVVDGAKGPQAANVVRL"
     gene            complement(50804..51973)
                     /locus_tag="PC512_001209"
     CDS             complement(50804..51973)
                     /locus_tag="PC512_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase domain-containing protein"
                     /protein_id="HDF2440974.1"
                     /translation="MGGVALKILKNKNKYIKGIMAFVFLSLATTAGVFLINDLSMKNM
                     EEKVMESANVEGDDVKDQYKLLLENLFDYRNKAILEKNENILKGLYETDKKFGLWAYE
                     NEVKKMKYLENWSSKQGVKFKDIKTRVKIKKIKEKEKDLYGIICSVSTEYKYSYENQK
                     DKENAFRIGTYHYLNVKIIDNQYVITKEWYTDPFADSLNLENIKSDDIRNYIGQQDGV
                     ELQLTDEQKKAIDYAHKYCGAAADEEHGMKFNPNYRDYNPEGGDCANFASQIMFESGR
                     FKKNSIWNYSERAGTKAWVNAQAFKNYALYSGRGSLIAKGSYEEVYKEAYNLRPGDFV
                     GYEKKGRITHVSTVTGLDSRGYPLVTCHNTDRMLVPWDLGWSDKSIRFHIIKINY"
BASE COUNT        17328 a         8648 c         5933 g        20214 t
ORIGIN      
        1 taccttttgg aatatgatat attatattaa ttaaattttt ataagataag ttatacttat
       61 aggagggaac catataaatg aatatttatg ctcatagggg gtttagtgga aagtatccag
      121 aaaatactat tctagctttt aaaaaatgtt tggatatgga tatatatgga atagaacttg
      181 atgtccacag aactaaggat ggaaaaattg tagttattca tgatgaaaag gttgatagaa
      241 cttttaatgg acatggtttt gtaaaagact ttactttaag aaaattaaaa actctaaact
      301 catcttttga aggatatcaa agcaataaag aatgtaaaat tccaacttta gaagaagtat
      361 taattctaat ttcacctaca gaccttattt taaatataga actaaaaact gacaaaataa
      421 actatcccaa tatagaaaaa gacgttttag agcttatttt aaagtataat atgaaaaata
      481 gagttcttat atctagtttc aacagcaata gtttaaaaaa ctttcataaa ttagacccta
      541 gtataaaaac aggattatta tgttatttac ctataaacaa tgtagtcaat tttgctaaat
      601 ttctgggtaa tagttatctt catccacctc tagttttagt aaatgaatct ctaattgaac
      661 tttgtcacaa aaatctactt ggtgtcaatg tatatactgt aaatgaagag ggtgatatac
      721 tacactgtct aaaactcaat gtagatggta tttttactaa ctatccagat attgcttcaa
      781 atcttttaca ctcaaaacaa tacagctaat tatacaatag tttgtactcc ttgactttta
      841 tataattaat atgtacaatt ttattaaatt tatcttggag gtataactat ggataactta
      901 ttaaatgaac ttgaagcttt aaagagtaat ttagataatc taccaataga aaaaatagaa
      961 aattatgatt tgagtaaaac tgctttattt ataattgatg ttaataatgg ctttgcaaga
     1021 caaggtgcat tatactctcc tagagtagag tctttaataa agccaattga aatgtttaca
     1081 aaaaaaatat caaacaaatt aaatagagta atagcattta ctgattctca tactcctaaa
     1141 tcaatagaac ttttgagtta tcctgttcac tgtttggaaa atgatgtaga aagtgaattg
     1201 gttgatgaac ttaagtcgat agaaaaccta caaattcttc ctaaaaattc tactaatgga
     1261 ttttttgcat tagaaaattt ggattttgat aatatagata atataattat agttggcgat
     1321 tgcacagata tatgtatata tcaatttgca ataactctaa aatcatattt taatcaacat
     1381 aatattgaaa aaaatatagt tgtacctatg aatttagtag atacttatga tattcctaac
     1441 gttcaccctg ctgagatttt aaacttagta tttttcaaca gtatgattca aaatggagtt
     1501 aatgtattaa aagagattcg ttaagcttct aatactttac atcccatata atacaattat
     1561 cagatattta tttttaataa aatttctaat agaaaaacac agttttagtg agaagattac
     1621 aatttaaaac actatctatt attactaatc ttcacaatat aaaaaatcgc agtttagata
     1681 ttccttatac aaatttataa ggaataataa attgcgattt ttatttttaa gtagtacaat
     1741 taatttatac tacttcagta tttaaattca ttttttaata atcatactta ttcgtagttt
     1801 cgcacattac tacctttatt tttttattaa acatattctt atattctaat aaaaactcat
     1861 ttagttctga atccataaga tttatttttc tatcactaca aagcattatc ttttcttggt
     1921 cgattattac attaatatca tttaagtcat tttttataaa tgttgttata caactctttg
     1981 gttggatttt ttctccatat ttctcataaa atcctgcact cttcttaaat gactctaaat
     2041 cttctgtaga tactttgctg gaagtattat tactcataaa acctgctgta gaagggtcga
     2101 ttccaaagtt tctaagttgt ttttctactt cttcagtgtc cataccatat ctctccataa
     2161 attgcttttg tattttcata aatttttctt gagatatgtt gttatctctc atataatcga
     2221 atatttttct tgaaaactca gccatagaca tctttccatc cataacagaa aaatataagt
     2281 tatatatgta ttgctcaaat ttatctacat cagaatcttt aactttgttc tttagttcgt
     2341 taaagtctat tattctatca tcagacattt ttcatcctcc tagctaaatt tttacttgta
     2401 taagattata ccatatttct attatattta tatacacact atttttttaa tttaacgatt
     2461 ttttctgtag catctaattc gcacattctg cccaaaggaa tagttatcat tgggatacaa
     2521 tgtcctgact gaagattata tatagaaggt ttattgacct tatttgcaaa ttctattagt
     2581 aattccatca aatcattttc ttcaatacaa tccttaaaat ctccaaaaat tataccatta
     2641 cattcctcaa gttttcctga agaatatagt tgtgttaaca ttctatccag tttatattga
     2701 ggttctccaa tttcctcaat aaacaaaatt ttatcttttg catctatttc atattttgtt
     2761 cccattgtgg caattattaa ggataaattt cctcccatta ttattccctc tgctttacct
     2821 tcacatacag tataaatctt ttcttctttt ggattttcta aatataattc atctttaaat
     2881 tctaaagcat ttaccaatga tttataggta aatttacccc atttacctac atttgctgcc
     2941 attattccat gatatggtaa aagaccacaa tttttataga aagctaaatt taaacctgtt
     3001 atatcagaaa aacctataaa tggttttgga ttttgcttta ttatatcata atttatttta
     3061 tccaatattc ttgttgttcc ataacctcct cttaagcaca taattatatc tacatcttta
     3121 tctaaaaaca tatcttctat atcccttgct ctaatatcat cattaccagc taaataacct
     3181 ttataattta aactacaact ttcagaaaac ttaacttcgt aaccataact ttctaaatta
     3241 aactttattt cctccaaact tgtatttctt aatggcccag atggcgcaat tattcctaac
     3301 atttaaacac ctcttcttat aaaatgatat attcttctcc atactaaata tctctaatat
     3361 aattataaga tattttattt gtacttgata cataataatg atttacataa aataatataa
     3421 ttaatgaaga aaaataaatt tttaatatag ttaggatgtg ttttatgctt aatataaaaa
     3481 ctctttgtca tgagataaat gattgggtta taaatataag aagagattta cataagactc
     3541 cagaacttgg attagaagaa tttcaaacta agaaaaaaat tattaaatac ttaaatgaaa
     3601 taggtataaa ttatattgaa tataagaatc atacagggat aactgcatac attaacgtga
     3661 gtccaaactt tgaaacagtt gctataagag ctgatataga tgccttacct ataacagaag
     3721 aacttaatta ttcttataaa tctattaata ttggcaaaat gcatgcatgt ggtcatgatg
     3781 cacacactgc tattttactg ggtacttgta atatactatt taaattaaag gattacttaa
     3841 atgtaaatgt aaaattcttt tttcaacctg ctgaggaaac tattggtggg gctcaactta
     3901 tgatagaaga tggatgtctt gaaaaaccaa atgtaaaata tatatttgga ctccatgtaa
     3961 atcccaatat caacaaaaat ctaattgaat taaaatacaa cactctaaat gcttccacca
     4021 atacacttca attaactgta catggttcaa aatgtcatgg agcttatcca catcaaggta
     4081 ttgatgctat tgttatatct gctcatatta ttacagctct acagacaatc gttagtcgaa
     4141 acacaaatcc aactgattct gtggttattt ctctaggaaa gattgaaggt ggaatcaaag
     4201 aaaatatagt ttgtgacaaa gtggttataa ggggtacttt gagaaccttg actcctgaaa
     4261 ctagagagtt ttcaaaaaaa cgaattagag aaatttgcga ttttacttgt aaaacatttg
     4321 gaggaagtat ttctgttgaa attgaggaag gttatccagc tcttatcaat tcaaaccatc
     4381 tagtagatta cgtcaaacaa aatgctgtag aattgtttgg tgaagaaaat attatcctta
     4441 aagactcgcc cactcttggt gctgaagact tttcgtattt tctaagacac tgtgaaggag
     4501 ctttttacca ccttggttgt gcaaatcgtg aaaaaaacat tacttcccct ttgcatacct
     4561 ctacttttga tattgacgaa gattgcctta ttactggtgt catgctccat gtaaaaaatg
     4621 tattatcatt ctaactatta atatttttat ttattatttt atattgaccc tcacatgatg
     4681 tcatgttata ccctaaaatt acaaatgata aattaaatag ttggaggtaa tattatgaaa
     4741 gaaatattaa taaatcctat aggtaaaata tgtattcaag gcgaagaggt ctttattaaa
     4801 ttagacaaaa agtatgtacc tgcattaaat gaactcgacg atttcagtca tttaaatgta
     4861 ttttggtggg ctgatgggtt tgataatcct gaactaagaa gtattttaga aaccccaaaa
     4921 ccttataaaa gtggaccaga cgttatagga atatttgcaa caaggtcacc tataagaccc
     4981 aatccaatag cattgactgc tgtacaaatt atcaatatcg accatgaaaa tggcataata
     5041 aaaataccat atattgatgc taatgataat agtcctgtta ttgacttaaa gccatatact
     5101 ccaagcgttg atagggttga aaatccgtcc gttcctaaat ggtgtagtca ctggcctaag
     5161 agtgtagaaa aatcaggaga atttaattgg gaagatgaaa ttgaatttta aattactttt
     5221 ttcttgattt cattaacttg ttttccacat ttattttatt tacacttacc aagattttat
     5281 gtcacatata catataatat taggctgtat tatataatac aacctaatat tatataataa
     5341 atttctattt ttcccttaaa tcattcacat tctttctaag ctacataaga tttttctatt
     5401 atttcttttt gagtttaatt tagcattatg ttgaggaaaa aacatttcat gcattttaat
     5461 aaattaaatt tttcttttat tctgcgattt tataataatc aatttaactt aaaaataata
     5521 cctaactatt ttaactatgt taaactagta aatgtaacca cttatatgtt acaattttat
     5581 ataaacatca aatataaaaa actatataaa taaatgacac atagtgttat atttttttat
     5641 accaatttag ttatttttca gttacagatt taataatagt taatagtaag acataatatt
     5701 tttatgccct ttattgatta tgtattttct gttatctgtt attatcatca ataataaaca
     5761 taagggggta tatattatga aattgtattt aagtgctgat atagaaggta cttgtggtat
     5821 tgtaaattgg gatgaaacaa aacttgaatg tgaattttcg caacactata gaacgcaaat
     5881 gagtaaagag ataacagcag catgtgatgg agctactcaa tctggtgtac atgaaatact
     5941 tgttaaagat gcacatgaca gtggtagaaa tattaatcca aatattttac ctgaaaacgt
     6001 caaaatactt agaggatgga ccaaagaccc actagttatg atggcaggaa ttgatgaaag
     6061 ctttgatgca tgtatattca ccggctatca ctctggagct acttgtaatg gtaatccact
     6121 ttctcatact atggatattg attatgacta ttttaaaata aatgatgaaa tagcatctga
     6181 atttactata aatgcttata ttgctgcata ttataatgtt cctgtagcat ttttaagtgg
     6241 agatgaaatg ctttgtgaga gtgcaaaaaa actaaatcca aatatagtca ctgttcctgt
     6301 gtcaaaagga attggaaatg gttcaatttc aatccatcca aaccttgcac taaaaaaaat
     6361 tgaaaaaggt gtcaaaaaag ctttatctgg agatttatct aggcacttaa taaaattgcc
     6421 agataaattt aagatagaaa taaaatttag agaacattat aaagctttta aggcctcttt
     6481 ttatccaaat atgaaaaaaa tagattctca aacagtacta tttgaaacag aggactatta
     6541 tgaattttta agaatgttat tatttatata aatttcatat cataaattaa ggagttgatt
     6601 aagataagta ataaaagaag gattccttta ggcgaattta tttctgtatt tttatttttt
     6661 gctgtttttt ttggtataac tttttgtatt ttcacggtta taggaattgg cttcttatca
     6721 ttcttaggat ttgaatataa atctcttgga gctgtattaa ttttcttttt aatatatttt
     6781 tgtataacca ctccaattga ttttctatgc actactattt tagatatatt cagatatgta
     6841 aacaaattac catactcaat atataaactt tgcgaattta taattgattt tatactaact
     6901 tttctagcta tgaacataat tgataccttt atggattcag taacgattcc tttaagtaca
     6961 gaaatcttat tcgctttact ttcttatctt ttatcagaat gtatggattt ttttgatagg
     7021 gataagaaaa aaccttaata aaaaagatag attccttaat agaacacata ttttcgtatt
     7081 tctattattt aatctatctt tattttattt aataaatttt tattaattaa aatatagttt
     7141 cttctatctc cttagtcatt tgcttagcac tatcaaaaaa ttcttctata tacactactt
     7201 catcactgac cctagaatat tctgctgcaa atgccattac atgactttgt atagcttctt
     7261 ttgctgctac tctacccttt tctagttctt tatttgaaac taatttaata aattcagcta
     7321 taagatttct atcatattcc tctaccatat tctgttgatt tgatggattc ataactattt
     7381 cttcgttttt tccaaattct ttaattctta tctcattttt atttaaatcc ccaccaactt
     7441 caccatggct aaacattaac tttatagttc ttccattttc tttagtaaat gcacataaat
     7501 taaaagtagc cgtcactcca ttttcaaact gtagtatatt taccatattg tctacaacat
     7561 tattatcaca tctgtaaaca catcttccat atggacttgt cttaagtata ttcaatagat
     7621 tctcttcagt tggatttatg tgaacagctc tatttatact tctatctttt tctaaataaa
     7681 ttctctttgc tgaatatgga catttttttt caactaaaca ctgaagacaa ttttgtgcca
     7741 tctctccact agcattttgg ttattaagat gctttaagct tccaaatgca gatatttttt
     7801 tgcatctact tcctactaaa tataacaaaa tatccatgtc atgacaactc tttgctaaaa
     7861 ttaaagggct ggtttcattg ctatttctcc aattccctct agtaaagcta tgtgcaaaat
     7921 gccaatatcc tatattttca ttatattgta tactaactag ctctcctaat tttttgcttt
     7981 ctacaatttc ttttaattta ttataaaatg gagaatatct cagtacatgg caaatcataa
     8041 aaatcttatc tttatactta tcacacaagt catctatatg taccagacca tctaaactat
     8101 tagacattgg cttttctaat agtacatgat aacctttttc aagagctagt tttgctacat
     8161 cataatgtct atcatcattt gtagctatta ttactgcatc tgccatcttg tcatgtttaa
     8221 aaaagtcttc taaagtttca aatacatttt tactatctag gttatatttt tgtgtaaata
     8281 gttctcgtct tcctttttta ggttctgcta cagcaactat ttcacataca tcagaatttt
     8341 cataaatata tggagcatat gcatacgttc ctctattacc tgctccaatc acagcaactt
     8401 tcactttttc catactttaa tttatcccct ttatattatt tatactactc tattatagtc
     8461 tatttttaca gacatttgga tatttttaat aaaagaaaca gcagttataa tttttcaatt
     8521 ttaactgctg ttataagtta atataccaaa catttttaat taaattttct ttaattttaa
     8581 tacaaagact taaatattaa atacaaatta taaaaacact tttatctagt ttacttcttc
     8641 ttttctttgt ctaatttatc taacttctta ttgtataaaa acatataaaa tgctgccgaa
     8701 aatactatta aatatccaac aacacttaac atatctggat agacattgaa taagaatata
     8761 cttaaaattg ctgaaaagat tatattacta tagtcaaata tagagatttc cttagcaggt
     8821 gcatatttat atgctagagt tattccaaat tgacctagac ttgcaaatac tccacctagt
     8881 aatagatata taagttgcat aagggtcatt ggttcatata ctgcaaaagc aattggccct
     8941 acagtaacta atgaaaaaac tgaaaagaaa aatacaattg tatagtaatc ttctctatct
     9001 ccaagaactc ttaaacaagt atatgccatt gctgcaaata cagctcctgc aattcctcca
     9061 agatatggaa ttacttctac actaaatgtt ggttttatta tgaataaagc tcctataaat
     9121 gcaattataa tagctcctat ctgctttaca tttatttttt cttttagagc aattgcacaa
     9181 aatattacta caaggaaggg actcatttta tttagcatat tagcatctga aagcatcaac
     9241 ttgtcaattg catagtagtt aaatataact cctagagttc caaatattga cctatataaa
     9301 agtactttta aattttcttt tttaccagtt agacttcctt tatgttttat gataagccaa
     9361 aaagctatta tagctgatac cagatttcta aagaacactt tttgaaaact tggtaaatct
     9421 ccagctagct ttacgaatgc agacatcatt gcaaagccaa gcgctgatgc tattataaac
     9481 attatacctt ttattcgatt tgatttgatt gtgctactca tacgtacctc ttttctatat
     9541 aaatgtataa agccatatta attaaaaact tagcttatac attaaataat aattatctaa
     9601 atattccaat ttatactata attaaaagtg taaactatgt caagtaacta ataaatcttt
     9661 tcaattaata acaataataa ttatagctaa aaagttatat gtttttatgg attattatca
     9721 gaatatataa tataatttta tatagtatag acttttttta atttattatt tagattttta
     9781 atagattttt taactatgga ggtatttaaa atatggaaat aaagagatat gaaggaactg
     9841 gaagaatgag tagagctgta gttcataaca atacagttta tttatgtgga caaactcatg
     9901 ctgaaggagg agtaattgaa caaacaactg aagttttagc taaaatagaa gatttattaa
     9961 acaaatatgg ttcagataag caacatttgc tatctgttac tatttattta agagatatga
    10021 aagactttga agctatgaac tctgtttggg atgcttgggt tgaaaaagga tttgaacctg
    10081 ctagagcttg tgttgaagct agacttgcta gagagcattt gttagttgaa atgagcgttg
    10141 ttgcagctac aaaataatca atttagctta taggaggcta tctcaaaaca gagagataag
    10201 cctctttttc attgttgaaa tgatgaaaat atatttgatt tcgtataaaa gaaagtgtct
    10261 cacgaactaa aaaattcatt ttgagacacc tcctcactat ttaatctata taaatttact
    10321 tattctctat tggcaatatc aatttagatg gatatttacc tccatggtaa atcgtattct
    10381 ttgcttctat atattcaata ctattatatc cctctgtcgt gttgctattt tggaaaataa
    10441 agtttttagc actagacgtt atatctagtc taattttatg accaacttta aacgtgtttg
    10501 atatttttga agttataatc gtaaacttat aaatctctcc ttcttccata aactctgact
    10561 tataaaaact atttctaaat ctagcactaa gtataccatc agctaattta attgaatttc
    10621 catctaaatc cacgtccata atttttataa cccagtcagt atctttggca gaacttgatg
    10681 caaaaaactc taactttata tcacctgtta cagtaaattc ttcactaaaa gcatctgatg
    10741 tataacacaa catatcactt cttttttcta aatctttgta gttatttgga actccaactt
    10801 cattctctga catatcaatt agttgtactg atgggtcttt tggattatat atataactat
    10861 catacttttc ttctaaatca ttatcaaata ctaatctacc atttcctaaa gatgtgttag
    10921 catttccatc acttattaga tacatacttt tatctatctt atttattatt ggccaatttt
    10981 cttctgtctt ccacttatta gaacctacag agtaatactc tactggagca gtcgtatcta
    11041 tgttattttc tatacctttt aagtatttat caaaccataa tagataatta taatccaaat
    11101 catatcttaa tgaactattt cctaaagaaa taccatttat atctcttaaa gtatttgaat
    11161 tatgcatcca tggacctaga atagcctttc tctttccttt ttcatagtcc tttataacat
    11221 ctaaggcctc tgtagttccc atactattat catcatacca cccagataca accaatgcag
    11281 gtacatttat tttatctttt tgtaaatgcc agtccatcaa atcccaatac tcatcttttt
    11341 ctactctctt taaccattct tccagaaatt caattctata tccaagagct tcaacaggta
    11401 tattttctat tggtcgtatg tttaaaacat catcccaatc atctcttacc attttgcttc
    11461 tatcaacttt atttcttgat accataaatg cccatgcaag cataccagat acaaaagctc
    11521 ctccttttct tggtatatca ataaaagggc ttcctgatgt tactatacta actaaagctt
    11581 taagatgctt attgcctgaa gatgcagctg cccattggac ataaccaaga tatgatgctc
    11641 caagcattcc aactattcca cttgaccatt cctgtgatac tatccaattt atggtactat
    11701 ctccatcttc cctctcatga atcataggtt cccacttacc ttctgattca tttcttcccc
    11761 taacatcttg tattacaaca gcatatcctc tttgtacata tttataatat atttctttat
    11821 cattttcttt tccatatgga gttctcataa gaattgtcgg tgcttttttg gcagaatcta
    11881 caaaatcagg gagatataca tctgtagaaa gttttatacc atctttcata tcaatcatat
    11941 aatttccacc aaatcttata gaatatatct cttcattttt atgagttttt tcccattctt
    12001 ttaatacagt atactcttca tatccatcca taattaatat agtacaagtt tctctagata
    12061 aacagataaa acctactatt ttattatcta caataattat atctagtggg aactttttgt
    12121 ttctttgaac ccatatatat tcattaagtt tagaatgcgt ttctcctaag ttatttataa
    12181 ctgtgtcttt atctgtgttt actaagcttt tagtatatac atcaaaatta ttaaataaag
    12241 actttaaatc tatttttgta agatttaaat aatatgtatt ttcttctttg cttattggtt
    12301 ttaaactttc tattttattt gtaaaaggat tcaacttttc aattaataaa tctccatcaa
    12361 agattacatt tccactgtat agtccagata tgtataattt aaattttatc aattaaactc
    12421 ccccctataa tcctagagac atctttattg catatgccac tgatatacct gcataatttc
    12481 ctaatactcc accaattact cccattacga ctgctacact tacaagcgaa ttccactttg
    12541 cagaagcagc tactaaagct gaagtaggac catcagcaat tgctcctact atagaaagta
    12601 ttacatattg atactttatc tttaaaagtc tagttatgcc taaatggaaa acaaatgaag
    12661 caaaaattat actaaaacag taaagtgtta tagtaaaagt tgaacctaaa aactctttta
    12721 tatctactga aaaacctatt gtacataaaa agaataatgc aacaaataat cctaaatcta
    12781 aatttccctt tagtttcttt actggcttta attgagcaat tataattgaa attgttgtaa
    12841 ctaaaagtat tcttgctgca ctactaaaac ttgaattgaa atatccagca agtattgttg
    12901 aaacttctgt aacaacaaaa cctatagcca acatccaagc tatatcttta atactccatt
    12961 cttttgactc cataaattct tcattttgac aatcttctaa ttctgattct tctacatgat
    13021 atggccaaag ttttttaaac ttctttgaat tttttaatat tgctggtaga gcaaacataa
    13081 atatcaatgt tggtactcca attacatagt ctgctgcatt tgctgctgca agagtttgtc
    13141 tacttacatt aagacctgtt ccaatagctg taagattagc acttccacca gtatatgtac
    13201 ctacaaacat tccagcaacc ttccaacctt ctgatatttt ttctgcaaat actaatccaa
    13261 ataaaaatgc catgatactt acagttaata cagctacaaa aattgcaatt aaaggttctc
    13321 ttgataattt tgtcatttct tttaagtcaa cactcatcaa cattatagtc atagaaattg
    13381 gaatagcata tgttgaaata gttccatata actcagtact tactggaact acttttaagt
    13441 ttgaaagtat tattcccatt atgattattg taagtgctgg tcctaagctt ttaatggctt
    13501 tgtatctttg taagtaaaaa cccaatgcaa tcattgatgt cattacagca agtatactac
    13561 ctggatttga aaaaagtgta ttcatattta acctccaaat ttatcataag tttacttcta
    13621 ttcctaaacc tggtttattg acaagattca taatatctcc atccattaca aatcctccag
    13681 atataccttc taattcttca caaaacataa aactatcaag gtcagcttct gttatgttct
    13741 ttttagatgc tattaaattt gctgctgctg ttataccaat tctcgtttcc agcatacatc
    13801 ctaacataca atttactcca cttgcctcag ctatgttgtt gatttttata gcaggatata
    13861 ttccacttga tttcatcagc ttaatattaa atgtatcaac tgcattcttt tttatagcct
    13921 taattgcatc tattggtgaa tgtaatgatt catctatcat aatttttgtg ttacttttat
    13981 ttcttatgta agcagtacca tctaaatccc aatgtggaag tgcttgttca attgcatcaa
    14041 cattaaattc ttctaacttt ttgatagtat ttatactgct atttacgttc catccttgat
    14101 ttgcatcaat tctaattctt atactctctc caacggcttc tctaattaac tttacagctt
    14161 caatatcgtc ttcaggattt atacctgctt taagcttcaa tatcctaaaa ccttctttta
    14221 ctctttctaa agcttctact gccatttttt ctggcttatc tatacttata gtaatatccg
    14281 tttggacttt actatcaaat cctccaagaa ctttataaag aggtgcattc ataatttttc
    14341 ctttaatatc atataaagct atgtcaatag ctgcttttgc agaagtatta cctataataa
    14401 ttccatccat gatggtatgt atggtttcaa tatctagtgg gtctttgcct attaactctt
    14461 ttttaaacat aagcaatact gaaagaacat tatccaaaac ttcacctgta actgctgcaa
    14521 gaggtgctgc ttcgccaaat ccacaatacc cttcatcagt ttcaattttt aaaattatac
    14581 tttctccata ctcaattact ccaaatgaaa ctactacagg tttttttaat ttaattctaa
    14641 gcttttcaaa tttgatatct gttatcttca tattaccctc cttatttttt gaagttataa
    14701 ttcaattttt aaaattttat actttaaatt atattattac ttcaatatat atgtcaagat
    14761 aatttactga aaatttactc ttttccaaaa tataatgtga taatcttaat tcaattaata
    14821 ctcttctatt aaattttttt attattattt tctttgtatt aatttaacaa taattcattt
    14881 tcatagactt ttatttggat ttaattaaat tttaattgtc aaaatctact atgtattctt
    14941 attgccacta cttctatgtt gtgctataat tactttgttt taagcgaata ttttatatta
    15001 attttattat ttggaggttc ttatgctagg tgaaaagatg agaaatataa gaaaaagcaa
    15061 gaaaaaaaca ttaagtgatg tttccaaatt gacagattta tctataagtt atatctctca
    15121 aatagaaaga gatgctattg aaccatcctt gtcttcattg agaaaaatcg ctgaagtttt
    15181 agacactcct ttatatatgt ttatggatga caataatact gatgatttag tcattagaaa
    15241 agaagataga gttatgatga aatttccaaa gagtgaaatg ttttacgaga tagtatctcc
    15301 aatgcctaca actgagttta caccttcaat tttatttgta gagtttgaac ttaaaccaga
    15361 aagtgaggat gccaaagatt atatatatca tgcatcagaa gaaattatgg tggtaacgag
    15421 tggtgtggtt gatatttgta tgggtgaaaa ggtagttaga ttaaatccag gtgactcaac
    15481 atttataaaa gctaatgtac cacataaaat catcaatcca agtaaagata caatagctcg
    15541 tggatatgga gttatatcac ctccaatttg gccaataaaa tctaaataaa ctcaatatga
    15601 cacacctact ttttgtagat aatataatag atttaaatat tgcttttatt ttaaatttaa
    15661 aatatttact caaactaaaa aaatagctat ttgactaatc taaaccatct taattatggt
    15721 aaatagtaaa tagctatttg taagttatat tataaattat aataaaaatt gtatttgtta
    15781 aaattaaact gctatatcat ttaatacttt tgcctttaca actcttatat ttttcatact
    15841 cttgtagata tcttgaatct tatcttcttg ctctctcaat agtctatgtg cttcatatat
    15901 atctacaagt tcaaatttta ctacatcatt tggctttgct tgtgctaact tatacaaatc
    15961 tacacttata acgttcccta tcttagtata gccaccacta gtctgtctat ctgataacat
    16021 tataatcggt tttccatgac caggtacttg tatagctcca taagaaatac catcagatat
    16081 aatatctgct ccattaaggt gctttatact ctctccatct agtctacaac ccattctatc
    16141 tatttcattc gtaactttgt atttatttga taaaaatttc tctacttcac cgttagaaaa
    16201 agcatcaaat tgaggacctt ttacaattct tagtacgatt tctgaactat aagttggaat
    16261 atattttgaa cttaattttt tatttattgt aaaatctttt tcctgaataa aagtatttat
    16321 ataatctcct tttttaagtg ctctaccttc aaatccacca attttagctc ttgtataagt
    16381 tgacttactt cccattgcaa gtggaacatc tattccacca gctattgaca cataggctct
    16441 agcacctgat ttcacacctc taaatgataa tacatcacct ggatttattt gatatgacct
    16501 ccagttttga atttcttttc catttatttt agcccctaaa tctcccccag ttactgctat
    16561 ttgcgtatat tcatcaaagg taattgtagg acctaacatt aaaacttcta aagaagcctc
    16621 atcttcagaa tttcctacta atatatttcc tactctatgt gcatactcat ccattgctcc
    16681 acatccagat acaccatatt gaccatagcc aactctacct ctgtcttgta ttaatgtttg
    16741 gaaacctcct aattcaactt tgaatcccat atataccact ccctgtacta taacgatatt
    16801 taaatactta agttattttt ttcgatttct ataaattcat ctaatgttat tggaacaaat
    16861 tttataaaat ctccagctct aagcaaaatc tgttcttctc tattttcatc atataatttt
    16921 aaaggtgtcc taccaattat ttgccatcca ccaggactat caataggata tacaccagtc
    16981 tgggaacctg ctattccaac actcccacca taaattttag tccttggcac ttctaatcta
    17041 ggtgtagcta ttctttcatc cataccacct agatatggaa atccaggagt aaaacctagc
    17101 atatatatca agtactctct gcttgtgtgt atttttataa cttcatctac agtgagatta
    17161 ttgtagcttg caacgttttt aatatctata ccaaaaacct catcataaca tactggaatc
    17221 tcatgtattt taggttttgg taatactata ctttccaaat tatcttctat tttttttaaa
    17281 ttctcaatca aactatcaaa atctatttct aatggattat aacttatcat aagtgaccta
    17341 tatgttggta ccatttctgt tacaatacct ttaagattcg atatttctat tgctctcata
    17401 aatgaaatta cttttttgtt tatatcttct gatatctcat ttccaaattc agcaaccact
    17461 gccttatccc ctgatatcaa gtatctagtt tccataaatg tcacctcttc taaattaagc
    17521 aaataaagca cctaggctgc taagagaagt tattcctgta tatgcagata ttaaaactac
    17581 tattaatcca aatattaaaa gccatgtagg atgcttgtaa tctccaacaa tatcttttct
    17641 tttagatgct ataagcataa ttcctaatgt gattggaagt atcaatccat ttaaagctcc
    17701 tgctaaaatt aataaagtag ctggttttcc tataaatgcc attataagtg ttgatattgc
    17761 tataaatgct attataaaat atttttcata tttatctata aaaggattta gtgtctttaa
    17821 gaaagaaact gatgtataag cagctcctat aactgatgta attgcagcag accataatac
    17881 aagtccaaag aatttatatc ctattgctcc tgcactaaat ttaaaagctg aagcagctgg
    17941 attttctggg tcaagttgaa gaccttttga aaccactgcc agtattgcta aaaataaaag
    18001 aactctcatc attgtggcaa ctaatatacc caaaagagaa gatttagtta tttcttttat
    18061 attttcttct cctgttattc caccgtctat taatctatgt cctccagcaa aagttatata
    18121 acctccaaca cttcctccaa gtagagttat tattgggaat atcagtcctt ttggattttc
    18181 tggttttacc attcttgata ctgcctctcc aacaggagga tgatttgata ttgctacata
    18241 tccaactata attatcattc ctaatgctaa aaatttagtt atcttatcga ctagagaatt
    18301 tgaatttttt gacataaata caaatatggc tattaatcca cttaatacag ttcctaatgt
    18361 catattcata ttaaacatta cattcatacc aagtgcagct ccaccaacat ttcctatatt
    18421 aaaagctaat cctccaagag ctactaaaaa agctactaaa taacctaatc ctggtattat
    18481 tttatttgct atatcctgac ctctaagtcc tgatacacca attactctcc atacatttac
    18541 ttgagcccct ataaaaagga ttgttgtaat taaaattaca aatgaaaaat tcggtccaaa
    18601 atcttgggta aattgtgcag tctgagttaa aaaccctggt ccaattgctg atgttgccat
    18661 tataaatgca gcccctataa gtgctccgac atctttttta tttttagttt tatctgtaat
    18721 attttttgta ctcatatttt atctccccct catgttatca gtcttatact atgttctctg
    18781 acgaacaaac ttctatgttt tctaatggac aaacttctat actttctaat tcaaaacgct
    18841 ttcttatttc tttgacaaac tctattgctt ttggattgtc cccatgtaca catatagaat
    18901 ctgctttgat atgtataact tcacctgtta aagtttctac agttccttct tttaccatcc
    18961 taacaaccct atctattgca tgttttgtat catgtataac tgctccttct acatttcttg
    19021 gaaccaaaaa accattatta tcataagctc tatctgcaaa tacttcattt gcaaacctaa
    19081 gtccaatttc tttagcagaa tttatcattt cactattata tagccccaac agtataatat
    19141 ctttatcgac ttcatatata gcttcacaaa tccccatagc taactcttta tctttagctg
    19201 ccatattgta taatgctcca tgtggtttta catgttgtat attacatcca tttgaacttg
    19261 caaatgccat taaagcaccc aattgatatt ttgtataatc tttagcttcc tgctttgtta
    19321 ttttcatctc acgtcttcca aatcctatta aatctagaaa acctggatgt gcgcctattt
    19381 tcactccatt ttttttagct agctgtactg ttttttccat atgactaggg tcacctgcat
    19441 gaaacccaca agctatatta gctgatgaaa tatattttaa aacttcttca tctaaaccaa
    19501 tcttatacgt tccaaaactt tctcctaaat cactatttaa atctacttta tacaatttat
    19561 gacccctcct tgctaacatt ttgatagaat aagtagtttt aatttttaaa ttttgtttat
    19621 tttatatatt gcatgaaata ttttatcact tgtattcaat tttatttttg caactattct
    19681 attgcattta attaatataa ttttaccatt taaggaatat ttttgcaatt attttaattg
    19741 aacattcatt tgtatttctt tttcaaaaaa tctttttacc attttttagt taataattaa
    19801 ttattttcac ttaaaataag ggctttaacc tttattttta aagtattttt catttttaat
    19861 cactttatat gcaagacaga atcatttttc ttcattcatt tgtttctttc atctatataa
    19921 ttatcattct ttgtaagtaa aatatcttta tatttttata attaattctt tatatagttt
    19981 taagtataat aaaatcatgt atactaaatg catgttaaaa tattatttta aaacatgcac
    20041 aatatttgta catattgtag acatataaac ctataaatta tacaatagta ttgttaagat
    20101 tatatatttt tttaacataa attttgtatt gggggaaaaa caatggataa aaactatacg
    20161 atgccaatat accaaaaaat agcgttggat attgcaaata aaatatacac gggtgaaata
    20221 caagaggatt cagtactatt tggacgctct gttttggctg gtaaatacaa tgtatctcca
    20281 gaaacgataa gaagatctgt caaaatttta gaggacattg gcgttgttaa aagcataaag
    20341 ggtaaaggtg ttattgtact atctccagac aaagcttctt cttttataaa aaaatataga
    20401 gatattacaa atatatcatc atataaatca acactttata atttaataga tactaaatct
    20461 aatttagaaa atgaaatatt agatactata aataaaattt tagactattc taacagactt
    20521 gaaataatca atcctttagt gcccgttcag ttcaccataa attctaattg caaatatatt
    20581 ggtcaaacag ctgcacaaac taaattttgg caaaatacag gtgctacaat agttgcaatt
    20641 aaaagaggtg aagaacttat aatatctcct ggaccatata ttgaattttt agaaggagac
    20701 attctcttag tagttggtga ccaacacatt tacaattcta taccaatgtt tttatatgaa
    20761 aacgaaaaat aaattatata atttagtatg attatataaa aatgcaaaat taacaacaaa
    20821 aaaagagctt catattttac ataaagctct ttttaaattc aaataaattt aactttgatt
    20881 aatttttaaa tatccaattc atcttctttt tcccagctta aagctctcga tacagctttt
    20941 ttccatcctt tatataattt acatctcttc tcttcactca tatttggatt aaactctttt
    21001 tctactgacc actttgaagt aatttcattt cttccaatat agaatccaac agacaaccct
    21061 gctaaataag cagctcctaa agctgtagtt tctactattt tgggtctatc tatatctaca
    21121 tttaatatat ctgattgaaa ttgcattaaa aaattattat tacttgctcc accatcaact
    21181 tttaatgatt ttagttttaa ttttgaatcg ttttgcattg cttctaaaac atcctttgtc
    21241 tgataagcaa ttgattccaa tgtggctctt actatatgtt ctttttttgc tcctcttgta
    21301 agtcctaaaa ttgaacccct agcatacata tcccaatatg gagctccaag acctgtaaat
    21361 gctggcacta catatacacc attagtatcc tctaccctat ttgcatacat ttcactatct
    21421 tttgcagatt caattatctt taattcatct ctaagccatt gaacagatgc tcctccaata
    21481 aatatacttc cttctaatgc atatgttact tttccatcaa ctccccaagc aattgttgta
    21541 agtaacccat gcttagattt aactatgtta ctgcctgtat tcataagtaa gaaacaaccc
    21601 gttccataag tattttttgc agtaccttct tcaacacaat tttgaccaaa taatgctgct
    21661 tgttggtctc cagcacatcc cgcaataggt attttagctc ctgataacat gcgctcatct
    21721 gtatgaccat aaacatagct agaaggtttt actaatggca acatgcttat tggtatgtcc
    21781 aattctcgta atatatcctc atcccattct aaatcattta tattgtacat cattgttcta
    21841 gatgcatttg agtaatctgt tacatgtact tttccacgag ttaaattcca tattaaccat
    21901 gtatctatag ttccaaataa taactctcct tgttctgctt tttccctagc tccttctaca
    21961 ttatctaata tccattttac ttttgttgct gaaaagtatg catctattaa aagacctgtt
    22021 ttttctttta ttgattcttc caatccttta tttttaagtt catcacatat ttctgacgtt
    22081 ctcctacact gccatactat tgcgttataa ataggtttac cagtatacct actccaaaca
    22141 accgtagtct ctctttgatt agttatccct attgaagcaa tttcttctgg tcttatacct
    22201 gctgtttcta taacttctct cattacccca ctttgtgacc cccatatttc catagggtca
    22261 tgctctaccc atccagcttt tggataaatt tgattgaact ctttttgtgc aattttcact
    22321 atttcgcctt ttttattaaa tagtatagct cttgaactgg ttgttccttg gtctaatgcc
    22381 attacatact tcttttccat caccatattc tccttatcat ataatattta atttattaaa
    22441 aagaaaaatt taatatcaca tatttcaata aataatcata cttaagtaca aatttaatat
    22501 aatagatatt tagtaagaag acacttattt tctatcatat ctatataata atattataca
    22561 ttatagctta catattgatt aataaatttt aaaggagtat aataaacagt gttcataata
    22621 attttaataa aagaggtggt aatatgccaa agattttaga aaatgtaaaa gaagatatat
    22681 taaaagtgtc tcgggatatg attttagaag aagattactc gaatattagc ataaggaaaa
    22741 tagctcaaag gtgtggtata agtgcaggta cagtgtataa ttactttaat tcaaaacaag
    22801 aaataataga atatatcaca aaatctgaat gggatttatt gataaggcga attgaatact
    22861 ccaataaaaa cactgaagat tacataaaaa aactaaacat tatttttact gaaataagaa
    22921 attttataaa caaagttcat aatatccaat acaatgactt tttaaacact tttgaaacag
    22981 agagattttt tgaaatgaaa aaacacaaag acgactttca tgaacagctt tcaaataaag
    23041 tatatgaagc tttagaaaaa gaaagttttt ttaataatga caaattagta tgcaatatca
    23101 taataaaaat gtttttttca tattcaacat atcttcatat agaatttgaa gatttaaaac
    23161 cctatattga aaaattaata cattaaggtg gtgtttacct tgaatcataa tactagtatt
    23221 aagaacaagg acagtaatcc aaaaatattt ttagtactta cactttatct attaggtata
    23281 tttatgggag ctattgatac tggaatagta tcaccagcaa gaacgattat acaaaatagc
    23341 cttggagtaa atgaaaaaac gggaatttgg atgattacca tatacacatt aacatacgct
    23401 tctgtaattc ctatctctgg aaaattagca gataaaatag gaagaaaata tgtgtatcta
    23461 gttagtatat ttctatttgg tagtggttca ttaatatgtg gattatcatc actattttcc
    23521 aatttctata ttttattaat tggtcgtgtt attcaagcaa ttggtggtgg tggaatcatg
    23581 ccaattgcta cagcagaatt tggaactacc ttcccagaaa acaaaagagg catggcttta
    23641 ggtttagttg gggcaacata tggtattgcc aatattttag gttcaagcat tggtagcaca
    23701 attctaagta tatttggaac tcaaaattgg aagtggctat tttttgtaaa tcttccaatt
    23761 tgtttaatca tacttattgg tggagttttc tgtattaaaa acaataagtc tgaatctaaa
    23821 gaaaaaatag ataagcttgg tacattgatg ttgatatgta taatcgtatc actattatat
    23881 ggtcttatga atatagactt ttttaatttt aaaaattcta tacaagatat atcagtttat
    23941 ccatatttat tgacatttat tgtacttata cctattttca tatttattga aaatagagct
    24001 aaagacccta ttttaagctt tgaatatttt ttaaatccga gaatattgat agtacttatt
    24061 ttatctttaa ttgttggtat tggaatgatg ggtatggtat tcgttccaca gtatgctgaa
    24121 aatgcattaa agataaatgc tggttctggt ggatattttg tagctatatt gggattattt
    24181 gcaggtattg ctgctccttt aagcggaaga cttattgaca agtttggggc aaaaaaaata
    24241 ctattactag gattttctgt atctatgata ggctctcttt acctagtttt aattgctcta
    24301 aaaaccaata ctgtatttag tgtatgtgta agtttaatat ttatgggatt aggaatggga
    24361 tttactatgg gaactcctct aaactatatg atgttatcaa atacaagatt agaagaatct
    24421 aattcagcac ttgcaacatt atccttgata cgctcaattg gtacttcaat ttctccagct
    24481 ataatgattg gatttatagc acatgcagga ttatctgtgc aagataatat tatggactta
    24541 gttggaaagc cctcaactcc taaaatagtt caacttgaag aacttgaaaa catgatagat
    24601 gacttaaaat cagaccctga aatggcaaaa aatttaaaaa atgtctctat cccaaatatg
    24661 aatgatactt caaatataaa tatggacatg acaggtggca aacttccaaa atccttactt
    24721 aataaagttc agtcagcaga tacaaccaac attaccaata taacaaaaga aatatcaaca
    24781 acaatgtttg atgaaaaagt tccatctata attactaaaa tacagaaaaa tgtacaaaaa
    24841 ggaatagatg gaacacaaag tggaataaac ggtattgaag atggtgaaaa taaactaaat
    24901 agtggtatta aaggagttca aactggtatt gacaatatgg taaaagctag agctggtatt
    24961 aatcaaggaa tagatggtgt aaaaaaaggt attgctggtg ttgacaaagg tataaaaggt
    25021 atggaacaag gtcttgaaaa acaagatgag gccatcaagg aacttacaac tgcttataat
    25081 aaaataccta ctacagaaaa aactcctact gataacgaaa ataactcaaa cgaacaaaac
    25141 cagagtaata ccagtaattc tgaatcagat gacactaaga atgattctac agaaaataag
    25201 aataacaatt ccagcgagaa taaaccaaat gtaaatgaac aaaaagaaag tttaaatgct
    25261 caaatacagc aactaaaaaa gacaagagat gacttaaata caaagttaca aaaaaataaa
    25321 actcaaaaga acgaattaag taaaaaacta agatcaatgg aatctcaaaa gaaagagcta
    25381 caaagcaagt taaataattc tataagccaa aagaaagaca tggaaaaaag ccttgataca
    25441 atgcaacagc aaaaaaaatc actccaagca gttttagcaa agacacaaga ggtaaaaact
    25501 gaaataccaa aggcttttga taaatcaaaa ttggattata taaattccat agaaaataat
    25561 agaacaaaaa tagaaaacac actacaatct actctaaact caggatttaa acagatgtat
    25621 ataacagtat tctgtgtaaa tctactagca tttataatat tattgttcta taaagaaaat
    25681 aaaactagat aaaagagtgt tatagtatta tattgtaaat ttatcttatt cttaaatatt
    25741 ttattctaaa gaataaattc ataaaatttt tgtaattgat taatataaat tacaatataa
    25801 tactattttt ctcttaatct ttttctcttt tacagacaat caaaaagcaa tcttagttta
    25861 tcgaaataaa tttatacaat ctattcatac acccctttac atttatataa caattaaacc
    25921 tattgttata tatacaaatc aaaataaacc atatattttc aactataata tgttaaaatc
    25981 atattatgag catattaatt taagcaaaat gtcatttaga ctttaattta gtagttttat
    26041 attataaatt tatatatttt taattttaaa tgtcatttag acattactca taaaaagaaa
    26101 ggagtgtatt ttgtggatac tttaggaaaa agaattgctt atttgagaaa ctccaaaaaa
    26161 cttactcagc gcaaacttat ggatatttta aaatttgaaa acttaggcaa gtatgaaaca
    26221 ggagatagaa aacctaattg tgatatacta atgtcaatag ctgattattt taatgttacg
    26281 actgactggc ttctctatgg taaagagaag gtaaatgtca atagtagtgt aaaagaagat
    26341 aaagaagatt acttacatgt tactaatgat gaaatgacga tattaaatct atacagacaa
    26401 ctaaacgaac gtgataaaat aaaaatagaa ggaatacttg aacttaagat atctgaatat
    26461 aaagacttaa aaaagcattc ctctaataat aatgaagata aaatggttta aacatacata
    26521 atttgatacg attttacatc atctattaac cttctttttt tgtagtatat tactaaaata
    26581 tggatattgg attatttaaa aacaagtata gtctaatttc aagcacattt ataatattta
    26641 gattatctta tccatatttt agtttaagta ctttgaaaaa tataatacat ctctatgtat
    26701 aacttatatt cctaagaaat gcattactca tgtttttaat tcttccaaca tctttctata
    26761 cacaattgta catccttcat aattcccctc tttaagaagg attgaacatg tactagaata
    26821 tttagttaaa gtatttaatc tttccatatt taagcttttt atattactga gtgctgtaat
    26881 aaaatcatca attgctctac aacactctat aaccccatct gaatccaatt tacacacaag
    26941 aatattcacc tactttatat actatttatt aatcatcttc tgaatattct atattaagta
    27001 attgataaat tgatgattta tattttttac ctgttcttct tccatttaaa atagctgaca
    27061 aatagttttc attaacacct attttcttcg ctaattccct ttgagtcata tttaattcaa
    27121 taagtctttg cttgacttgc actcccaaaa aaggtatcca tttttttcga gcatccattt
    27181 atcaacttcc tttctaagcg atttatattt acttttatat tattttagct tacgcacccc
    27241 ctctatttag tatatatttt taatatgtac acatattaag tatataaatt tatttaatac
    27301 taaataagat tttttgatta ctttgtgcta aaattaggat gtaaattcgt atcattaagt
    27361 taattataaa gtcattttga ccttaagtca atggttttta tgtcattttg acctttaatt
    27421 tgaaactatt tacatcttaa aaagtctttt tgacattaat tgaatggaga gtgtttatgg
    27481 atactttagg agaaagaatt gtttatttga gaaaagcaaa aaaccttaaa caatatgaac
    27541 tagaagaaat gttgggctgt gacaacttaa gtaaatttga gagaaacatt agaaaaccaa
    27601 attatgaaat attaaaatct atagctgaga tatttaatgt ttcagtagac tggctattaa
    27661 atggagataa tctatcacat aaatcagatt taatttgcga ttcctcctca aactatccac
    27721 ttaatagcat aaactctaat gaaataaagc ttttaaacaa ttttagaaaa ttaaatgatt
    27781 atgataaagc taaaatagaa ggtatgattg aattaaaact tcatgaatat gaaaaagaga
    27841 aggatttagg aaaaattgag tataacaaaa ataaagatga gaaaatagat aaataatttt
    27901 tatgttgctt ttgatacgat tttacatcat ttctttgttc taatattttt atttcattta
    27961 ttttcttttt tataatttta tgataaaata attagtatat tttgctttac ttgaatgtaa
    28021 ttatttatac aaaagtcaaa cataatataa atgtagtaaa tttttagttt caagtaatat
    28081 ctcgttatta taactaaata tttattaaaa ttaggaggat aaaatgggct taagagacaa
    28141 attcgcgcaa tcatttgcta gatcaaaaac tatgagtggc cctgagaaaa aggctaatga
    28201 aataatgggt aaattgcttc ttaagaaagc tatattacct atcgttttaa tgttcgtgat
    28261 aataatcgct ggagctatgc ttaaaatcaa ttcttgggtt acacttggca taaatttagt
    28321 tattgctgtt ggtgctttct tctacataag aaattctagt aaaaagtatc agaactttaa
    28381 accttatgtt ggcaatttga ttagtttaga gaaaaaaggt aaaaaagagt acgttgctat
    28441 tataaaacaa ggtaagttac cagttaagtt acaaatagct tatggtggtg aagaccttga
    28501 acatgttaag aaaaatcaaa tggttcaaat aagttataat ccagatgcta aaatagctat
    28561 tttggttaat agacaataat ttaataaaaa aaaggagttg tcttaaaatt gattttttct
    28621 aatcaaattt aagctcaact ccttttttaa tttttatatg ttatttttat tacttttttt
    28681 aattaatatt ttaaatatta aatccttctc aataaaatag tgaactatct acaatactac
    28741 tttatctttt cctaacaata tataatctgg tgctactctt tcatgttata caccattttg
    28801 taacatacct tttatatcag taacatcttc cttaatttcc tctacatctg ttttcattat
    28861 acccatttga acaagtatat ttttgtttat ttcttgttgt tgtgtagata attctataaa
    28921 attttctaca gtttttttat acatgtctct atcttctttt ttctcctgca tagtattttt
    28981 aaataataga gcacatagta tacctattgc ccctagacta ctcaattcgg ttattaattt
    29041 atccattata gcctcctatt gtctaaattt tttatactta tagctttaat ttttgttgta
    29101 ttcttacatc atgcaatatt atattttcag gattatcaat ttaatcttct gtactttaaa
    29161 ttgtaggtgt aatttataga ttgaataaat aataaatata tatacaagtt ctaatgtaac
    29221 aaaaaataag tacaaggctt acttattaaa gttaagacct tgtactttac ataaaaaaaa
    29281 taactaatac atagttattc taaatttact attcaactgg tatttctaat tctttacatc
    29341 taattctaac ttgctctcta attactgctg gtacttcttc tattgttttt ttgcctctta
    29401 aaattaaagc tacatatact tctaccattc cactctcacc tccagatttt cttacactaa
    29461 aagtgcttat attacttgct tcattgacag aactttgatt taacaacatc tcatatattt
    29521 ctacatttgc tataaaatta tttgttatat catcatcttg ctttacttga cctatactta
    29581 tgtctgaaat gtctttatac tgcatttcta cttttctacc ttgtttgatt tgttctattt
    29641 tatttttatc gaatttaaac aattttcaca cctccatttt aagcttgtgg ctcgttgttt
    29701 tcagcatcat atctaaaaat catagatgga cgttttatag ctgtccattt atctcctttt
    29761 tctactatga ttttaggctg agcacttttt atgttggctt cttctaattc atagatttct
    29821 tggtaacttg agtctgattt tttgatttca actagtttca tgtctttgaa taagtcagat
    29881 ttatttattt ttacttgaac tttagtttta tttattaatt gatatatagg attgttttcc
    29941 atcatatcat cctttaatcc ctcatttaat gttactatta agtcagtgtt attttcagta
    30001 atgtttatga ttgaatatac tttattgttt atcattaaaa tagaatcctt ttttacttta
    30061 agccctgttt ctgatttaaa tataaacata cttgaatata aatcgcctgt aggactactg
    30121 gctttaatca gtatcttatt ttctcctaat actattttat tttgtggtat ctcaaatata
    30181 atgctattta tttccaaatt agtcttagta gatattaatt catcatttat aaacatttca
    30241 agtttttcta taacattatt agggtcttgt actacaactc tcacttgaga tattgatttt
    30301 tcaactattt ctatagatgc tttacttgta tctacttttg ttatcatgta tattgtatca
    30361 tctgaaagct ctatatctaa aatatcattt agatgttcag gaattggtat tttagtaaat
    30421 tcatataaat cagtaattga tatagatatt ttatacatag atttattttt accagttatc
    30481 catagactat tatcattttt aattactagt atgtggtcat cattatgtga cttaatttct
    30541 ttaacattag ttaatacttt agtaaaagtt cttattatct tatctttttc actttctcct
    30601 agtccaaata atccatttgt attgtaccct tgagcgtaca actctccctc attagttaaa
    30661 acaagtgtca ttgagttata tatacttata tctttaacag aaggtaatcc agtaaccttt
    30721 tgtaactctc ttacatcatt attgtggcca actcccaatt ggtactcagt attctttcca
    30781 tatgaccata gagtattatc tgtcttaata atataggagt agttatctcc acaagcaact
    30841 tttttgacat ctgatatatt tacttcagta agagttaata attctatatc ttcaagggtt
    30901 tgattaattt ctttatatga attacttcct attccatata acttgccatc cttagcaaca
    30961 gccaatgaat gtgtttttga tatatcaata tcagatacct caaatggcaa tattattgaa
    31021 gtatacttaa aattatcttt aaatatgttt ttataattta tatacttatt atttgttttt
    31081 atatacttat cattaaacat tactagcttt tcatttttct tattaaaaac tattttatct
    31141 gatgtgttat ctgttttaaa atatgaatgt agggaacctt caagagcttc atttttatca
    31201 ttatcatatc tatggtgaat acctaaatga ttatatctat tatctcctgt tgaagaataa
    31261 aattttccat atatatcttt aataaatata gtattgtaac tagaaaatac agtatcaaca
    31321 tctttcttta tagatacttt ataatatgga actgacatat ccctataaga ttcatcagat
    31381 ataccataag tatctctacc tgatgatatc aaattgttat tattatctat ataaagtgta
    31441 ttattagctg ttacaaaaac atctttaaca tcttccacac tatttgtatt attattattt
    31501 gctatacttc catatccact aagacctcca acaaatagtt tattgtcatt tgttaaaatg
    31561 gctgaagtat atccattaac tactattttt tttgcattta taatattatt aattactcgt
    31621 atccccttta tatcattagt ctctgttgaa aagaataccc tctctttttt ccctgtagta
    31681 taaatcatat tgtcatttgt tataaaaaat gtagcttcac ttcctgctgt cacaacagat
    31741 tttacattct caatatttat ttttgtaaat gtacttatac ttccttcagt aaacccaaaa
    31801 tagccattta caagtccaca tacatagcat gtattatcat ttttaacaat gattgataca
    31861 tcattacata gatatacatc tctaacacca tttataggta tacgtgtaaa tatattccta
    31921 cttgtagtat cacccaatcc taactgtcct tttccattat tacctgctcc atataaaaga
    31981 ccatcattag ttaataatag agatgtgttt ccatatacag ctacatattt tacattttca
    32041 acatttattt tagtaaatat atttctattt acattatctc ctattcctaa ctgaccagaa
    32101 ttatttaaac caacagcata acaggtatta tcatttttta tcgcaaatgc atgtttacta
    32161 ttgtcagtaa atctatttac atttatagat tttatattat caatatttat tttagtaaat
    32221 acctttctat ttatctcatc tcccactcct aattgaccta catcatttaa accaacactg
    32281 taaagcatat tattattagt taataaatat gtagactttg aatggctata tatttcttgt
    32341 atattagaag atatttcact actgctattc tttttattgt aatttatctt attatttaaa
    32401 tttaaactac tattaactga tataccatgc gtacccttag agttatatcc acatataaat
    32461 aagctcttat cagttaatat tgcaaatcta gttttatctc tacttaaatc ataaggaggt
    32521 ataaatatat tttttatatt tttcattacc tttttataat tagtggcatt atatccatct
    32581 tgtgtatctg aaacatctag ttcttttgca ctttcagata tattcccaaa accatatagc
    32641 gtgttagaag ataaatacaa tagagcttta tataaaaata tggctttatc agaggtaata
    32701 ggacctgaat ttatattaga tgctgcaata ttattagatg attgattgtt aagataattc
    32761 cttccatatt gatgtatata agatgaacct ccagaaataa gtaaattatc tggattgaca
    32821 ttttttaaat tacttgacga ttccccatta tataaataag caaaagttgt agaagatgat
    32881 gattgtgtac atcttgtagg ataataatta tatatataag aatcaagata tcctgcatat
    32941 gaaattccct gatattgaac tctatagctt gaatcagttg gttttgtcca tgaagtacca
    33001 tggtatccag ttagaaaaga tccaatgttt gtacaaaata cagttacata ctcatatatg
    33061 ataatattat taattttagt aatattattc gtgcatgaaa ctctactata acttgaccct
    33121 gatatattta tataatacca atcacttaat aaacctagat ttacattaga tccatcagaa
    33181 gtactaaaac ctaacaggta atttgtattt ataccagttg catatacctt tttttcatca
    33241 actacaataa atgttgcatt atatgaacta taagcatcag ttacattact aaggctaatc
    33301 tcagtatatt gacttattaa tgcattacta agtccattaa cataacttga actctttcca
    33361 gaagtgtata tttgcttatt attagttaca attaatgaaa accagtttga taaatcagta
    33421 tttataacaa ctttttttac attatctata gatattttct taaatacatc tgaattagaa
    33481 ggaagaacac ctgctattga gttactattt ggtccagaat aataacaagt atcatcattt
    33541 ttaatgtaga atattcctcc agaaatattt tttgatgcta ctatagactt tacattagag
    33601 atacttaatt ttgtcaactc atttaattga cttggtaagt cagaacccat tcctttgtat
    33661 ctattatttc ctagaccata tacatctcca ttccctaaaa taaccagagt acaataagga
    33721 ctaaaaacga catctcttac agaatgtata tctagtggaa gttcaatatc ctttatttcc
    33781 atttcttctt ttaataaagt taatttatcc tcagatttaa ttaaatttat ataattacta
    33841 taactatatt tttcactatc cattttctta aattctacaa tgtgcatatc atcaaaaaac
    33901 gaacctaatt gtccataagt attatctcct gtacaatatg aatcattatt tgaatcaatt
    33961 agtatgctat gtgataaacc aatgaaaata ttcttagcta caatattttt taaatctata
    34021 aatgaattat ctatattctc agagtaattt gctataccta actgatatat atcattattt
    34081 ccagcaacct ttaaagtacc tttgttatct ataagcatag tgttaccatg accacatgca
    34141 atagttttta tatttacttc ttctatctta gtaaatagtg atgattgaag tgcatttcca
    34201 aaacattttt cctttccaca accatatata tcattattat acgtcattaa cacagtgtgt
    34261 tcagaaccac aagctatagt cttaacatca ttaatagaaa ctaaactaaa taaatctcta
    34321 ttattcttat ctcctaaacc tagttgacct tgattattaa aaccagtaga atagcattta
    34381 ttgtcattct ttattataaa agctgattta ttatatgaaa atacagcctt tacattgtca
    34441 acatctactt ttgtaaatgt atttacattt gcagatgctc cattagttcc tagacctaat
    34501 tgaccataca aattatttcc agcaacatat aaagttccat cattgtataa aagatatgtt
    34561 gattgaagtc cacatgcaat atcctttacg ccttttattt ctggaacctt ctcaaatgta
    34621 gaaactgttt tccctacttt ttctaatccc aatcccattt gaccatctgt atttatacct
    34681 gcgacaagta attctccatc tgaagtaagt ataactgcat gagattctcc acatgcaact
    34741 tttttaatat tggtagatat atttggtatt ttcgtaaata attttcttgt tgtattgtct
    34801 tctcccaatc caagttgaaa gttactatta tctccacatc catacaagat attattattt
    34861 tttagaccaa atgtatagtt acaacatcca gtaaaaaaat taataaagtc ataattatca
    34921 tacccttcat caaattcatc aactaccata tttttatcgc caaagaaatt acctctttga
    34981 agtagtttag ttcttttcat tataaaaacc tcctaattat cttatttcat acgaatattt
    35041 atttaaagtt atatctgtct gaccaattga atatgcccta ttagattttg tttcaacaaa
    35101 gttattatcc atttcatgta tatatctaac tctatttgca ttaaatggta gcaccacatt
    35161 cttaaatgta acactaccaa gttctccagt tatacacttt ctatttaaat ctaacttaag
    35221 gccttctata gctattatgt ttttagcatt agttaaggta tcataccaat atccagcttc
    35281 atctacatct atttctgact ctaattctaa gtatattaag atatctaata ctttttcaga
    35341 taatttattg taactatttt ttaatacaga tagttcagtt tgtatttgac ctcctattac
    35401 atcatcaata gatatatttt taattttttc tactacctca tttatagctc ctgataagtt
    35461 tttagcttct gtagataaga gttcttcgcc aatttttact tttatttctt ttatattttt
    35521 atcaaactta tcatctaaat cttgaatatc cttttgagtt acaaaaacca acgtcgggtc
    35581 tacttctaat gtaacatttg aagtattgga caattgtaaa atcattttta caaccaaatc
    35641 tttaatactg ccatcttcag cacgtggctt atacgtctct ggatacttac ctatagctat
    35701 tatattattc tcattatcca gaacagcagc ttctcttatc ataaatccac caactgttcc
    35761 tggtaaaata gtctctataa ctatccaatt aggatttttt tcatcaattc ttagagaatt
    35821 tatatttcct tcccaaacta cattctttaa agcagtttgt tcctctgttg gctcataata
    35881 ttctccatta ctatctccaa cttgaaactt ggttaatcca acaagctctc ctagtgcagt
    35941 tgcatttgct attttttctc taccaatttt ggttaatatt atataaaatt tttcttccaa
    36001 ttataccacc tccgatttag gataaactac tacattttct acacctgtat catttgcaat
    36061 agctatatta atcttacaat tattttcaat gcatttaatg cttaaaggat aaacctttat
    36121 ttcttctcta cttatcattc cagctccaca gtttacaaca gcactacatt ttataattgg
    36181 ttcaaagtat ggatgaactt ttacctcttc actacatacc atacctccac cacaatagac
    36241 catactttta tctagtatta ttggttctaa atagtgtaat aagtgagcag gttttactct
    36301 ttcaatcata tcgctacaat ctaaaagagt tttatagtca cagttatttg ctataaaact
    36361 caatacgaat gtaaattcat cactataaac ttttatatct gtttctgatt ttgtatatgc
    36421 ctcacatata ctttttataa cttcaatagt actagtacct ctgcttctca ttttagcttt
    36481 tatattgcta cgtcttgtgt caaaatcaag ttcttttttt tcaatgcaga gtatgtcttc
    36541 ccacatatct aatccccatg ttgcagtgtc aacaaataat tggttaaagg tatcatcaat
    36601 atcttcttta agaatattta attctgtatc gtatgcacct tgtatctcct ctacaatgta
    36661 atttctatca aatgatggta gtttatcaat tagcttcatt gattttccac ctcactaaaa
    36721 ttaacagttg ttacactagg tattttatct tcattaatag ttatattatc tgtacttcca
    36781 tttataagta ggttacttaa atcgtgtaca ccagtagtat ttataagtat tcccattact
    36841 tttgtataga ttatctctcc tctaatatct ctaaagtatg tatttatact ttctaggaaa
    36901 gattctttta cattgtctaa tgtatatcca tcttctagtt tcattactgc acttatactt
    36961 atttctattg gtaatggtgt cacaactgtt atagttggtc caataggctt ctcttcatct
    37021 atatgttgct gacacctttc aattgtttct gtatcaacag cttgattatt tttcccaaat
    37081 atcaagacct taactgttcc cggaccatcc catcttggat aaaccttaac attatagact
    37141 ccatctactt ccaaagccca ttcttcatag tgagctttat ttccacttgt agcttgattt
    37201 ctttggattt tataaaatct ttcttttagt tcttcatctg tctctatatc tgtaccacct
    37261 tcaaaacttc ttgtgttagt aatctttgtt actccagata tattatcaac tagtttaaat
    37321 tcacaatttg taggtaaatt atatttctta ccaacttcca gagcttgaac tgggctattg
    37381 tcaccttctt cactaccaat agttacatct tttattacta caaatagtaa atctctatat
    37441 gatattattg tgccattatt tattacagta cctttctctc caataaattc aacttctcca
    37501 tttgactctg tacctaactt tctatataca ccaaattcat tgactctttt atcaagaaac
    37561 tggttatatg tgtcttgtat aaaagccatt ttatgcatct ttgaaagttc tagatatatc
    37621 ttcgaaagtt ctagattatt tccagatacc atgttgttta gaaaagaacc ttctccttta
    37681 taaatatcaa gattaatatt ttcaagagtt ctatttttta ttacttcata tgtctggtca
    37741 ctatacattt atttccacct ccccatagat agtggatact tttacatttg cactcaatat
    37801 gtctctgtta aagttagcac tttttacgtt tacttctaat atatatggat ttattagaag
    37861 ggcctctttt atgaatctac tagcttcact ttctgtaaga ccttttgtat atttttgtcc
    37921 tattagttct gaaagctctg tcccatattc taaagagtat atctcatgtt catatctatt
    37981 tgtctttata cacttgtata tccaaacttt taaggcttct tttttttcaa ttattttaaa
    38041 gtcacctttt tctaaaatag gttcatcttt ttcaaaatcc catgccactt cacgaaagat
    38101 tggcaattct tctgttttag gtaagatata atcctctggg acacctataa aaggaaatat
    38161 tgtactcatt ataagctcac caacttactt acaacagcaa atttttcgcc tattctaaac
    38221 attattacca tatccccaga ttcaaagtta tctataaaag gattttttac ttcatgctgg
    38281 tgttcttgat ttgtttctgt gtcaaatgtt tctagctgtc tatcaatcat ccaactatct
    38341 atcaaaatat cttctttttc taatatgatg ttatttgtct ctatttttaa atctggtaat
    38401 ttacttttaa tttttccaat aaaaaaagaa ggttgattat gatactttcc ttcttctctt
    38461 attattccta taaattcatt tattggatta gccattatat caccatcctt ttataatact
    38521 ctcctagctg tgttaaaatc tcttctacta cttaacttac ttattttaac tacatcacct
    38581 ttttgtggag catgtaaaaa ttctccatta cctatatata atccaacatg gctgactgga
    38641 ttatgaaaaa atactaaatc tcctgcttga agattttttt gttctacttt cttgcctttt
    38701 ttagattgtt gatttgacgt tcttggcaaa ctaacattaa cttttttaaa acaatagacc
    38761 attaaaccag aacagtcaaa actacttggt ccatttccac cccatttata aggtttacct
    38821 agatgttttt ttgcttctga tattactatt ttagctttat cagatacatt accagaataa
    38881 ccaccaataa taatttttcc ttttcttctt ccaaatttac tagcttcttc aacatttcca
    38941 aataaaatat ctatatggta tgttccattc ttttctatag ttattgcagg tcctacgtca
    39001 tttactttat agactccatc acgaccagaa actcctgtaa ttacctgtat ttcatctcca
    39061 tagtttaata aaggatgttt atttaaaaac tcttttgtat aataagtttg ctcatattta
    39121 ccaaccatag gagcagcgca agttttttta gatgggtcaa gttttttctt tctacaatct
    39181 gtatctccac cttcttcttt tctaggacag taagctgtaa attctgctgt aaactctttt
    39241 cctcctgcat aatcttctcc ccctaaatta ctttcttcct taggttcatc ctgtcctgct
    39301 gacttttcat ccataagatt ttgaaaatta agttcaagct caatttgata ttctccattt
    39361 tgccaagtat gtttgtctgt atctatataa aatagtccta caagctttgt ataagaatct
    39421 ttaactttta ctcctctacc agttatacaa cttacatctc cataaccttt aagagaacag
    39481 cttttttcta tcccattaaa ctcgctatca atatctacat cttgattttc ttgttgctga
    39541 attacttttt gcattattac atttacttcc ttaaaaattt cattatctat tttttcgcta
    39601 atcttgcttc catactggtc taccactatt actttatttt ttacattttc catgctctcc
    39661 gaaaaggtgg tatttataat attaaatccc tcttcaaaca taacacttaa tgtaacagtt
    39721 cctttttcaa taacattaaa cttatctaaa ttggcctcta tcatatactt tttctttgtc
    39781 tttttacttg cttctgtata tgcactcatt attgtgtcat aaccatttac tcctataaac
    39841 atctttgtat acttgacatt ggtctttgct attattccaa ctgaaagcct attttcagca
    39901 aatacttgct ttgctatgtc ttcaactaac ttatctttaa aattgtatga cacttcactt
    39961 tgtgtaagta aaaatcccat atctttagat acaaaactaa tttcattact gcttgaatct
    40021 ttagacctat taattatcat tcctctaaag agttctttct catctacata gaaacagact
    40081 gtactagcta ttggtatatc gatttgttgg aaatttacat caaatgatga ttgtattatt
    40141 gaaaactcta gtgtccttga tggagattta taatcacctg accatgatac cttgtctact
    40201 atgtcagtta tgtcatatat acttccgttt tttatgtgta cccaaatctt aataataaaa
    40261 aatcacctgc cttttcattt aattctatca gcagttattt ataacttatt atctataata
    40321 gttattgttt tggagttact tttggtatct ttattctttt atactctttt aaatctaatg
    40381 taaaatatac atctcgagtc ccatctcttt cttcataact aaacccttca attatgactt
    40441 ccatatttat atttgtttcc gtaattgtaa atcttaatat aaaaccttcc ttcatccatt
    40501 tttctatctt atttacacaa tcatatggtg atggaaaacc tgtatagtca cagaaagtat
    40561 agtctttatt tggaaaaaaa cttgatattg aaatgctttt aagagctaca ccaccaaaag
    40621 ttgctatttc acctattttg agtatactag aagagtttac agcagctttt ccattaatac
    40681 taaaggaaga tggaaatact ggaaatctaa atctatcttc agcttgtcta agccacattt
    40741 ccattataag acacccccta actgtgccaa ttggatactt gcaactaatt ttgatgttat
    40801 cttttctata tcagcttctt ctctaatcac tattgtatca gctaacttag ctatgtttat
    40861 atttccacca ttttttctgc ttctatattg atttgcttct tgtttagtta aaaccatttc
    40921 accttcatgg agtctggttt gatagtcatt ataaggaaca tagttcaatc caaatgcatt
    40981 attacctttc ttacctgaat aagctttacc agaatcacca gcctttgttc cagcatatgg
    41041 attatctttg taattttttt tactcttttc cactagattt aaaactgttc ctgtgatgct
    41101 tccatttttt atcttattaa tcatagtttg ccaccattta catatatctt taactatttt
    41161 acatacttta tctaatatgt taaaaaaagc tcccaatatt ggctctataa ttttccatcc
    41221 agtttccaac agaggtccta aggtctccca tacagttttc caaataacac ccagtgtctc
    41281 tataaaattg tttatttgag gtgcatattc acctaaaaaa gtaaaaattc ttgtgataat
    41341 aggactaaca gcttcaacta caggtccgat tagttggaat gctgtagtta ctattgtacc
    41401 aaatatactt attaatcctt gtgcaattgg tgatttattg tttatactat ctagtaaatt
    41461 atttactaag tttactactg gaagtaatga atctattaat gctgtaaaat cgatattttg
    41521 taatagtgta cttcctgcgt taacaattgc ttttggtgca ttccctatca ttgttgctgc
    41581 atgattttca aaacgttctt gcttattttc aaccatcatt ttacgctttt cagcctcatt
    41641 agaaattcga tattgagtag aatcagaaaa ctcttttcca ttttttacac ttctagattg
    41701 catctggtca tatttgttgc caataattat cttaccattc attacattgc ctattttacc
    41761 agccattttt tcagataagc cagctaaatt gcctaatcca ctttctataa aagtttttat
    41821 tttctttagt ccttgaccta aaatatcatc aaaaggttta acaatactct tcaagccatt
    41881 gttaatgctt gtttgagctc ctgatattat acctggtatt gtattactca tttctttagc
    41941 taaccccatc tgctttacac ttatgccttc caatgcttca tcaaaagttt tataattttc
    42001 tcctaccaga gtattaagag attccatgtt tccttttgct gcacttaaga aagctgctga
    42061 tacatcttgt tcactacttg tattcatatt taaagctcta acatctacca tagcttgagt
    42121 tatatctttt tcttttttgc caccagtaat attactaatc attttagctt tagttcccat
    42181 tgcaacaaca tcttcagggt caaaaggcgt atcatttgcc attcttacta aactgccata
    42241 ataatcatca acatctattt gattaacttt tccagtattt cttttcatta cactttctag
    42301 aacaactttc tgattttgtt cctgaccaag taaatcaaca ccctttttca cagcgacacc
    42361 tatagtagca ccatttgtca aatcagatat cttccctttt atcgaaccaa gtattccact
    42421 tgccatatcc tttacagcta ttgcaccact ccatacctta cctgcaaata atctcaattt
    42481 gggaaatact ttacttataa tgccacttgc catatctttt atagctatta caccactcca
    42541 aaaagtattt ttaaacaaca ttaacttagg caaaattcta cccatagcac tactcaccat
    42601 atctttaaga ttaatacttc cttgataagg acgtttctct acttgtttta attttcccaa
    42661 gatactactt atcactctct tagtcatatc ttttgctttt attacgatat tccaaatctt
    42721 gccaccaatc ttttttaaat ttccaagtaa tttattttta gttttttcta cttcatcact
    42781 tttagcttta aatattaata taatcataat atttgaatta aactcatttt tcttttgaat
    42841 caacttatta aaataatcaa taatcatagc tatagttatt gctagtctca taatacttcc
    42901 atttaaactt ccaataactc ctgaaacagc atttatgcta gaacttaatt ttgtcatagt
    42961 tgaacttaca ctactagcag tagtttgaac ttttcttaac gaggaattta aactgtttac
    43021 tctattactt gcacttccaa tagaattttt tatgctacta gccattacat tagtggaaag
    43081 tgaaacagcc acagttgctc tcctaaaatt atcagttact gatataattt gattcatttt
    43141 tggtgtgtaa ttatctgtaa ggtacatatt tataccttct tctctcacat ttcccattac
    43201 ataccacctc ctgtcaaagg acacactcca tatccatgtt tcattttttc aacttcttcc
    43261 tcaatttcta aggcgaaaaa agcttcaata agctttaatt cgcctttatc cattgcataa
    43321 aaaagggacg gtcttatacc ttttttcttc caataatagt acattattgt agtcctggta
    43381 tccgtcccta ttagtttttt acctcttcta tcactgcatt tttaccataa cccataacat
    43441 cttgaagtat tctatataag ttggtaattt cacctggtaa taataatttt cttgctaatt
    43501 cttttggtgt tggagcctta aatttatcca ttagctcctt atttttaaat aaaagctttc
    43561 catccaaatc acaaacacct tctataattg taagcatctg catctccggt aagtctatat
    43621 ccgttttcat attttcatca attttaagac aagtattttg tatttcttca tctttactta
    43681 ttgttaaagc tctacacatt actttaaatt cctgcccaaa tatagttgat aatctcttaa
    43741 gttcaactat agtacttggt ctttctaagt tttctgtatc tgaatttaaa agtaaatcta
    43801 ctatgtttat attttttgat aatccatttt cactcattat tatttgctcc tttatcaatc
    43861 aaattcaatc aactaacttt tttacttatt aactatctga atttattaag tatatactta
    43921 ctaaatatca gtataaaact aaatataaaa ctaaattata tcaagaaaat catactcagt
    43981 aaatgtgaaa ggagcttcta tctctccttt tactccaacc tcccaatcag ctaaagttaa
    44041 atcatcaaat gctatatttt ttactgctat tctttctgct ccataagaat ctgggtcatt
    44101 taattttgat atagcaacaa atctaggttc agaacctctc tttatctttt ctccaattaa
    44161 cttgtgcatt cttgaactaa cgtggtatag agttattgag ccttttcctt tatatcccat
    44221 atactttgta tcagtaccca tttgacctgc tattataata tcttcttttg taaattccat
    44281 ctttgcttga aatttcttta cttctgctac tttgtttcca tcaagccaaa gttctcccca
    44341 agtaccactc attacatttc tagcttccat atttgccata ttaataatcc tcctatattt
    44401 ctattgataa atctatatct tccatagcat caagtacttt tatttttgct tttaaaaata
    44461 ctttagaacc tgtgttagct tcttttattt cttgtaatgt catataagat aaatctactc
    44521 cttttgattt taaatacgat ttttgtgctt caaaatctat ttcaacagta gaatcagatt
    44581 ctataagtgc tgatttttct aattcttcta aataactttt tatagctact atcaataaac
    44641 atttgttgtc ataactgtta gtaacctttc ctatatagtc atctattatc acctttctta
    44701 tgtcactatg tataatatct aaagtgtcaa ctatttttat tttctggaac atttctcctt
    44761 tttctgctgt taattcagtt aaagaattta ctcctctagc aattcttata gctcctgctt
    44821 ctttaataag tataagctct cctttattaa cccttgattc tgcatcaact ttcgtcatct
    44881 taggtatatc gactacatca ctaagtttag tataagttac tgattgactt aaaggtgtac
    44941 ctgctataag tccagccacc ctgcttgtaa actcatcaac actgtatttc ttttctccaa
    45001 ctaacacatc ttctgtagta aaattaatta tcccttcatg atttcctaca acttttccta
    45061 atacagcttt aaccttaacc ttatctatat ctctaagttt aattatccaa ttttttatag
    45121 cagtcttatc agcttctact gcttttggca tacatagata attaaattcc ttagtctcta
    45181 aaaaatctaa tgcagtttga atatctgctt ctccttctat tacataaact aataatttat
    45241 ttggagtgtt aacatttccc atcaaagcta aatttatata ttctttattt tcagcagata
    45301 aatcaactgg tatatcctct ttttcatgta tttcattaag acctagtgcc ttagcatctt
    45361 taagtaccat tgcaattatt cctctagctg aacgttcttt aacagttgta gctagctcct
    45421 taaatgatat gttgatactt ggtaatccta tagccatact atcactctcc taaatttaaa
    45481 ttgatttctt tcatattttc atatactaca tcttcttcat atacactatc cagatagttt
    45541 agtgtaaatg taaagttcaa tacataaatt gactcttctt ttttaatact ttgttctagc
    45601 tttgttatat ttaattttct gtctgttacc tttatatttc tgttaaatag cttatttaat
    45661 tcatctgaaa tttcatacat tctaatactc tttgactgtg gttttggtaa gtattttata
    45721 gagataacaa tatctttgtt attcgtattt aacattacag gtgtacaaat aactgatagt
    45781 atacttacaa aaaaacaaga cccttcagag ccttgcacac tttcatcatc aataaaaata
    45841 ctttcagtaa agtttttttt gagaatctca ataattgttt ctaatatttc cttgtattta
    45901 agcaaataat caccacacta tcactaaata ttcttgctta atctgataat cttactataa
    45961 atgatataag tcatttttaa atatatatct catttattcc tgtcaagtat cttctatatt
    46021 tttaggtaat attattcttt tcaatctatc acctccttca atatggattt ctttcacaat
    46081 aacattatct cacatatttt attgcctatt gttgcaatgg tgtatataaa gtgttgtaaa
    46141 attgtcctat tttttataat atctcactca atttaaatat catctttttc tttaaattgt
    46201 agcaagatgt tctatctaag tgtagtttca tagaaatata tgtcatattg ttttttgtct
    46261 tactattata aaaaagatta aaaaattcca tttctatatc atttagacac gttagagcat
    46321 tttctatctt ctctttttct atttctatat cttctttttc catttttaat tttcttaatc
    46381 tttcctctct ttttaacacc tcattttcca cagaagagct tatgttatat gtgttactag
    46441 tcttttctgt atataccatt gctccacatc cagagtattc attctcacat ctttttatgt
    46501 ccaagttaat attctttatc tttatatcca aatacttata attatgtaat cttttatctg
    46561 tttctttaaa taatatatct tttttgtttt ccatagtact tccccttttt tatatactta
    46621 ttattagctt caaatttaca ataatctctt tagtgcacag ttttttacta atctcacaac
    46681 tttcaagaac atattgttct ataactgtat aaaaaaaact tcttctatat tttgttctaa
    46741 aatactagaa atcttcttag ccataagaag tccaggattt tttatacctc tttctatttg
    46801 agatatataa tcatttgtaa ttccagcctt tctggcaagt tgaatttgtg tcataccttt
    46861 gcattttcta taatatttca agttattttt aaacattgtt ttatacctcc attactatta
    46921 agaatatttt gttcttcctc acttagatta tatagaatta tttgttcttt atcaatagat
    46981 tttagaaaaa aatattcttt tatattttat tagttttatt ttttagaaca atttgttata
    47041 atctatacat aaggtggtgt tataatgttt gccaaaagat taagagaact tagaaaggaa
    47101 tttggattga ctcaaagaga acttggagaa aaagtaggcg tttcccaaag agtcttaggg
    47161 tactatgaaa cagaaaacag atttcctgat gaacacattt taaataaatt ggctgatgta
    47221 tttaatgtat cagttgatta ccttcttgga agaaccttag ttaaggaaaa tattgataca
    47281 gtagctgcac atagaaaaaa tccacatgaa gagttacctg aagaagcaca agaacaactt
    47341 aatgattata tagaattttt actaaataaa tataaaaaaa aataaaccat atgatgagca
    47401 gtctattttt ctgctctttt aatataattt aaaggcaaac atacattcta ttttaggggg
    47461 atttttatga ataatttgga taagcttttt gaattagctt ctcaagaaga gataataatt
    47521 cattatacca cttatattgc aggtgattta gaaggactat atataaacaa acatggtatt
    47581 aaaattatat cattactcag taatttaaaa caaaactcaa aaaaattgac atccatctta
    47641 gctgaagaac ttggacatca tttcactagc cttggatact atgtatcctc ttataacgat
    47701 tattatacaa aaattattat agataagtgc gaaaataaag ccttaaaatg ggcttgtgag
    47761 ttcttaatta ctgaagaaga tataataaac ataattaact ctggcatcac ttgcgtttat
    47821 gaaatggcag acatacttaa tgtggatatt actttctttc aaaaaagatt agaatttcta
    47881 tcattaaaaa aacagtcttt acaacttgga aataataaat atttaatatt aactaatttg
    47941 ccgtatttct acatatttga tccaatttca taataaaaat agtagtaatt ttaactggct
    48001 taacagtaaa atctatatat ttattttaac aaattttggt ttctataaat tcaatattaa
    48061 tatataataa tgatatcata ttatttaaaa ttctaaaaac aaatatatgc ttttgttaag
    48121 aaaggttgtt tgatgaatgt ataaagaaaa gttgtttgat aattatttta agttcttagc
    48181 actattattt tggccaatta tgtggtataa gtggatagta atttcaaatg gtactcttga
    48241 aaatatgtta tttaccatat atgcaatcgt cgcaattgtt ttcatcattt tatattcggt
    48301 gtttatgata aaatataaag acattacaca aatagatttc ttttacagga taagtactct
    48361 acttgctttt atatttacac tttttagctt tttaatatac ccaaagagtt tatttttctt
    48421 gtatttaaag attattttta ctggaatata cctttattat tcaatagtaa aaactcttaa
    48481 atttaaagat gacgaaggtg tagtgggtat tatgagctca cttttattaa ttgtaataac
    48541 tttgttctac taaatttaat tctatttgac ttaatatggc tttaaatatt agacatctac
    48601 attattttct gatattattt aagatggtag tcttatatta ataatgaaat acactatgaa
    48661 ggagttaact attatggaaa aaaaagtttt agcaacagtt ggagaaaaag agataactaa
    48721 tattgatatt gaaaatgcat taaaatcatt agacccttat caagctatgc aatttaaaac
    48781 tgaagaagga aaaaaacact tattaaatga tttagtgaat caagaattat tcttcttaga
    48841 tgctaaagaa gaaaaattag atgaagaaga aatatttaaa ttagaaatga aaaagataga
    48901 agaaaatgta ttaaagcaat ttgctataaa taaagtttta tctagtgtta atgtaacaga
    48961 agatgaaaaa gtaaaattct ttgaagctaa taagagctct ttctctaaac cagaaagtgc
    49021 aactgctaaa catatattag tagatagtga tgaaaaagct aaagaaatac ttgctcaaat
    49081 aaaatcagaa gaaatatctt ttgaagatgc agctcttaaa cattcttctt gcccatctaa
    49141 agatatgggt ggtgatttag gaacattcgg tagaggacaa atggttcctg aatttgaaga
    49201 agctgtgttc tctatggcta aaggtgaagt aagtgaacca gttaaaactc aatttggata
    49261 ccatataata aaattagaag accttcaaga aagtacagag tctacatttg atgaagttaa
    49321 ggctgaagtt gaaaaaagtt tattatatca aaaacaaaat gaagtttatg gaaataagat
    49381 aaatgctctt aatgctaagt acggaaacct tgtaaaatac aacgattaat cataaggtca
    49441 tatataaaaa agctgtcttt tcacaatatt tattagaaaa gacagctttt tatattaaag
    49501 tttaaatatt cagtttcata ttatcattct tttattgtaa agaactcagc ttaaaagttt
    49561 aaataagatt tttaattatc attagctaaa tttttatatc cacgtattat ctcataacag
    49621 taacctatta catctcttct ttttattatc ccaataaatg tgtcttggtc atctataaca
    49681 ggaatgaaat tttgatttaa agattttata actaaatctt caatatctgc gttgatggaa
    49741 acaggagaat tatccatttt tctatttata tctgtcactg gaacatcttc caatcccttt
    49801 aagtccagat ttaaatcatt ttttaatgtc cataaaaaat caccttctgt tatagttcca
    49861 acatatttac catccttact tattattgga attgcagagt atttgtgata ttccattttt
    49921 tctagggctt gccttatagt gtagtcttca tatatatatg ctacttcact ttttggtgtt
    49981 agaaagaata atatgttcat tacactaccc accgttactg aaaacttata aatattactc
    50041 aatatttata atgttacttt tttgcagtaa ctttctcctt tcttattttc taagtattct
    50101 taatactata cgctgtaaca agcgtttttc ctttgctcat tttaatctta ttatgcttta
    50161 ttaatatttt tatatggtct atcagtatca cttattctct ttttagaaaa tttactaaaa
    50221 attaattgac ttaaacttag ccataataat tttactctac actattaatt ttaacatatt
    50281 tatctcatta ttaatgattt tattttaata attttaattt attttgctat taattttatt
    50341 tacaaaaact gaaaaaaccg ctaaatgatt agcggcttat ctctcatatt actagaacac
    50401 taatatatat gaatttttaa ttataatcta actacgttag cagcttgagg acctttagct
    50461 ccatctacta cttcgaactc aacgctttgt ccttcttcta atgttttgta tccatctcca
    50521 gttatagctg agaaatgtac gaaaacatct ccttcacctt ctacagatat gaatccaaat
    50581 cctttttcgt tgttaaacca tttaactaca ccagttttca ttaataaatc ctcctaaaaa
    50641 aacacaaata tttagctact cttttctgta accttattac tactctatca tatatagcta
    50701 tgtttgtcaa ttattattat ttttatacat taataatcaa tttttttact ttataatttt
    50761 aaatgattat tatcttttac actttatttt tctttataat tttttaataa tttattttta
    50821 ttatatggaa tcttatggac ttatcactcc aacctaaatc ccatggcacc aacattctat
    50881 cagtattatg acaagttacc aaaggatacc ctcttgagtc taatcctgtc actgtcgaaa
    50941 catgtgttat tctgcctttc ttctcataac caacaaaatc ccctggacgt aaattataag
    51001 cttctttgta tacttcttca taggaacctt tagcaattaa tgaacctctt ccactataca
    51061 gtgcataatt tttaaaagct tgtgcattta cccatgcttt tgtacctgct ctctcgctat
    51121 aattccaaat tgagttcttt ttgaaccttc cactttcaaa cattatctgt gatgcaaagt
    51181 ttgcacaatc tccaccttct ggattataat ccctatagtt tggattaaat ttcataccat
    51241 gttcttcatc agctgcggct ccacagtatt tatgtgcata atctatagcc tttttttgtt
    51301 catctgtaag ctgtaactct acaccatctt gttgaccaat ataatttctt atatcatcag
    51361 attttatatt ttctaaattt aaagagtctg caaaagggtc tgtataccac tctttagtta
    51421 tgacatattg attatctata atttttacat ttagataatg atatgtacct attctaaagg
    51481 cattttcttt gtccttttga ttttcatatg aatacttata ttcagtcgat actgaacaga
    51541 ttataccata gaggtctttt tctttttctt ttattttttt aatcttaacc cttgtcttta
    51601 tgtctttaaa ttttacacct tgcttactag accaattttc taaatacttc atctttttta
    51661 cttcattttc ataagcccac agaccaaatt ttttatccgt ctcataaaga ccttttaaaa
    51721 tgttttcatt tttctctaat attgccttat ttctgtaatc aaataagttt tcaagcaata
    51781 gtttatattg gtcttttaca tcatcacctt caacatttgc agattccatg actttttctt
    51841 ccatattttt catacttaaa tcattgatta aaaatacacc tgctgtagta gctaaagaca
    51901 aaaatacaaa tgccattata cctttgatgt acttattctt atttttcagt attttcaaag
    51961 ctacacctcc caaatagtac accttacaaa tcaaattaca aagaatattc tgtcacatat
    52021 agtaattttc atatttaata attctctatt ttattatgtc caatattaaa aattaattgt
    52081 atcaatacac tgtttttttt acaatttttt attttataat cta
//
LOCUS       DAMJVG010000018        51987 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.018, whole genome shotgun sequence.
ACCESSION   DAMJVG010000018 DAMJVG010000000
VERSION     DAMJVG010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 51987)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51987)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51987
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.018"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(355..495)
                     /locus_tag="PC512_001210"
     CDS             complement(355..495)
                     /locus_tag="PC512_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2440975.1"
                     /translation="MENLMMSIITGVIASYIYDKLKSHSERPTKSGWELNIKFQKSKS
                     SK"
     gene            complement(753..1913)
                     /locus_tag="PC512_001211"
     CDS             complement(753..1913)
                     /locus_tag="PC512_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp27"
                     /protein_id="HDF2440976.1"
                     /translation="MKLNKTLLAIGMSVSLLIASCPTSNALSSINSIKGTNKYETAGL
                     IADKQNYDIAILINSENGLSDGLSASGLSGAKNAPILLTKKDTIPSETLKRLEKVKEV
                     YLIGGKNSIGASVQKILSDKKISINRISGTDRIDTSHKVAKEIGSVSAVKKVILTNAF
                     KGEPDAMSVASIAVRDKSPIVLTDGNTTSFATDGLETYAIGGKVSISDKLINETKATR
                     IGGVDRYDTNKQIINKFYNGSKEFYIASGTDLVYSLVGSTIAQKTPIVLVGNGSNKSI
                     LKNASKITAIGNIDDVVIKQCLNITNNVGDSNTGIVKDTNSNNTNKPSNEPSSNNPGL
                     TDKSTVYVTPNGKSYHLTKNCSTLKRSKTINKVTLKQAKSQGKIDPCNVCVK"
     gene            complement(2084..2287)
                     /locus_tag="PC512_001212"
     CDS             complement(2084..2287)
                     /locus_tag="PC512_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4236 domain-containing protein"
                     /protein_id="HDF2440977.1"
                     /translation="MGFNFRKSINLGGGLKLNLGKKSVGISAGVKGARVSVNSKGRKS
                     ATLSIPGTGISYTKTSTKKRKPK"
     gene            complement(2374..3408)
                     /locus_tag="PC512_001213"
     CDS             complement(2374..3408)
                     /locus_tag="PC512_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YHYH domain-containing protein"
                     /protein_id="HDF2440978.1"
                     /translation="MFKKKLIAVAMSITMISVGSFSYAHSGRTDSSGGHRDNKNKSGL
                     GSYHYHCGGYPAHLHNNGGCPYTGGGSSSGTATSVNNEEKQKRSVGEKGYNQGYEDGY
                     KGNYSSSNYSGDYSDTYESKYSEGYEKGKAKLEEEEKEAKETGYNLGLTGAKSNNTYE
                     KEVLKNAYDTGYSTGYNEYKTKKIEEYKAKGIEDSNKDKEKMTFEENIDSKFIDAYNN
                     AYDEIQEQLKNDYTTQGFESAIKGERFDTSTIGNVKYANWFKEGYDNGKVKLPKAKES
                     VYNQGYNEEDFSIPDEMKSIETKLKGVYDEGLEKREEEKSRNATYGVGAGTAAVVAGV
                     VYKKKKRKKI"
     gene            complement(3930..5291)
                     /gene="rlmD"
                     /locus_tag="PC512_001214"
     CDS             complement(3930..5291)
                     /gene="rlmD"
                     /locus_tag="PC512_001214"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HDF2440979.1"
                     /translation="MSVKKKDVIEFEVDKMEFGGTSLSQVGDRVIHMKGGISGQKVRA
                     GVKKVRSKKAEVKMIELLENSPLETEETCKHFRECGGCTLLSVPYEKQLEIKEKQVMD
                     LFLKQDLFGFQFLGIEGSPENKYYRNKMEYTFGDEVKNGPLTLGLHKKGKHIDIQTVE
                     ECMLVDEDFSKILVSSVEFFNEKKLPYYRTMNHKGYLRHLVVRKGIHTNEIIVNIVTS
                     SQEDFDMYEFKDMLLGIDLKAELVGVLHTINDGLADAVQCDELRVLYGRDYIQEEILG
                     LKFKISPFSFFQTNTKGAEVLYSIARDFIGDYNDKVVFDLYSGTGSIGQVMAGAAKKV
                     YGIEIVEEAVVAANENAKLNGLTNCEFIAGDVAKVVKDLKDKPDLIIVDPPRPGIHKD
                     AIRDICGFGAKEIVYISCNPKSLVVDLVDFKGYGYEIKMVKCMDMFPNTPHCETVVKL
                     IRE"
     gene            complement(5318..6040)
                     /locus_tag="PC512_001215"
     CDS             complement(5318..6040)
                     /locus_tag="PC512_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HDF2440980.1"
                     /translation="MAKKQRIDKILSNLGYGSRSEIKKYCKQGSVVVNGSEVSNPGTQ
                     VDTENDEILFNGEEVIYREYIYLMMNKPDGYISATTDKYDPTVLDLIDLSYLAFEPFP
                     VGRLDKDTEGLLVLTNDGKLSHRVLSPKKHVPKTYYAKIDGVVTEEDVEAFLEGVVLD
                     DGYKTMPSQLNILKSDDESEIELTIHEGKFHQVKRMFESVGKKVVYLKRLSMGNLKLD
                     ESLELGEYRELTDEEVKLIEER"
     gene            complement(6040..6369)
                     /locus_tag="PC512_001216"
     CDS             complement(6040..6369)
                     /locus_tag="PC512_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1904 domain-containing protein"
                     /protein_id="HDF2440981.1"
                     /translation="MPQIKIRGINENDICKISEKMINDLVEAVKCPRDYFEIECIKSV
                     AIRDGKIADVYPFVEVAWFDRGQEVQDIVARIITDSIRNNLDVESMDLAFTVFEKEKY
                     YENGEHF"
     gene            6699..7625
                     /gene="fba"
                     /locus_tag="PC512_001217"
     CDS             6699..7625
                     /gene="fba"
                     /locus_tag="PC512_001217"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-1,6-bisphosphate aldolase"
                     /protein_id="HDF2440982.1"
                     /translation="MALITTKEMFKKAYEGGFAIGAFNISDLEQLQGVLKAAKAKNSY
                     VMIQASMSAVKYAGPHTLVEMVKAASDEIGVDVALHLDHGPNMDAIKTCIDAGFSSVM
                     IDGSHFDFEENVRITKEAVEYAHSKGVVVEAELGVLAGTEDDVTSDVHKYTQPAEAVE
                     FVERTGVDSLAIAIGTSHGAFKFKGEAKLRFDILEEIQSKLPGFPIVLHGASAVDQNA
                     VATCNEFGGNIAGAKGVPVDMLRKASSMAVCKINMDTDLRLAMTAAIRKFLAENPKEF
                     DPRKYIGAGRDAIQAVVESKIDDVLGSANSIN"
     gene            complement(7760..9391)
                     /locus_tag="PC512_001218"
     CDS             complement(7760..9391)
                     /locus_tag="PC512_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2440983.1"
                     /translation="MDNNLIGLIEHVENPAILCKESGEIIYCNHLIDSIFSFLDIKKP
                     RNINELDSNFDKTEILTDSKKKIAFRELRMTAHIYNMKDNNNENNIVYLFEKSLISDK
                     VIEDIIEHIDEVVVVFNKDGVIEKMNTVSDEILPFKRTEVLGRNITDLVRQGLVEEPI
                     ILNMLKVKKKIYRNIVYPDGKLIAYTAVPRWDSKGKLTGGVLTGRDISRVIKLESQIK
                     YSDISEDTEYISQSKIMDNIKKVVKRAAASDSSIFINGESGVGKEIIARTIYKYSSRR
                     DKPFIAINCGAIPNELLESEFFGYEEGSFTGAKKKGKKGLFEEANGGTIFLDEIGELP
                     MQMQKKLLRVIQENTITRIGGSKPIKIDVRYISATNISHEDLRNNLKFRQDLYYRLSV
                     IPVKIPPLRERKEDIVPLVNYFLKLYNEKYNREVEVSPKVIELLEEYSWPGNIRELKN
                     IIERFVVLSAKNVIGEDEFNMLINLDMIDNETDDLSPIVVNGIMNLNDAYKIVDQIMI
                     SKAINKYGSITKAAEVIGIYPSTIHRKIKSGHIHV"
     gene            complement(9874..10911)
                     /locus_tag="PC512_001219"
     CDS             complement(9874..10911)
                     /locus_tag="PC512_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HDF2440984.1"
                     /translation="MNDIKDLSSYKNVWIFAEQREGKIAPVVIELLGEGRKLAKEVDA
                     ELCAILLGKDVDGLAKELITFGADKVYVADDALLEKYTTDAYTKVIKDAIDEIKPEIM
                     LFGATHIGRDLAPRIASRVGTGLTADCTKLEIDPEDKKIKQTRPAFGGNIMATIICPN
                     HRPQMSTVRPGVMDKAEKDETRTGEVIALDYKITQDDIRTTVLETVKTKKDLVSLTDA
                     NVIVSGGLGLGGPEGFEMLKKLADKLGGVVGSSRAAVDAGWIDHSHQVGQTGTTVKPN
                     LYIACGISGAIQHLAGMQSSDFIIAINKNPAAPILEIADYGVVGDLHEIVPMLIEKLD
                     SVDDLLEAIKA"
     gene            complement(10930..11715)
                     /locus_tag="PC512_001220"
     CDS             complement(10930..11715)
                     /locus_tag="PC512_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012703997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HDF2440985.1"
                     /translation="MKILVCVKQVPDTNEVRINKETGTLIRDGVPSILNPDDANALEE
                     ALKIKDEHDDVTITVITMGPPQADFMLRECLAMGADDAILLSDRAFGGADTWATSNTI
                     AAGISKVGDYDIIFAGRQAIDGDTAQVGPQIAEKLDIPQVTYVQDFKIEGKDIIVQRQ
                     LEDGYELIKVSTPVLLTAVKELNTPRYMSVDKIVKAYKHDVKVWTIDDLDVNKEEVGL
                     KASPTKVFRSFTPEPRGKGEILEGKADEIASKIIIGLKQKHII"
     gene            complement(11748..12881)
                     /locus_tag="PC512_001221"
     CDS             complement(11748..12881)
                     /locus_tag="PC512_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003483287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="HDF2440986.1"
                     /translation="MLYNKEQELLRKAVRDFVSKELDTLPAEMDKTGVMPKELIKKLA
                     DAKFISSNIPEEYGGGGAGYVSYAIVMEEIARRCASTATFVTAGSSLASLPILYNGTE
                     EQKQKYLKGIATGELIGAFGLTEPGAGSDAGGQQTTAELVGDHYILNGRKTFITNGPF
                     CDVAIVIAVTDRSKGLRGTSAFIVESKWDGFSTGAHEDKMGIRGTETSDLIFENVKVP
                     KENLLGKEGQGFKIAMGTLEVGRIGVAALALGIAQGALDEAVKYTKQRVQFGKPIAKF
                     QNTQFTIADMETKVCAARGLVYDAAQKRDAGMRVAQESAMAKYYASEIANEVAYKALQ
                     LHGGYGFIKDYEIERMYRDARIVSIYEGTSEVQKMVISSNVLK"
     gene            complement(12929..14056)
                     /gene="hadC"
                     /locus_tag="PC512_001222"
     CDS             complement(12929..14056)
                     /gene="hadC"
                     /locus_tag="PC512_001222"
                     /EC_number="4.2.1.157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(R)-2-hydroxyisocaproyl-CoA dehydratase subunit
                     beta"
                     /protein_id="HDF2440987.1"
                     /translation="MEAILSKMKEVVENPNAAVKKYKSETGKKAIGCFPVYCPEEIIH
                     AAGMLPVGIWGGQTELDLAKQYFPAFACSIMQSCLEYGLKGAYDELSGVIIPGMCDTL
                     ICLGQNWKSAVPHIKYISLVHPQNRKLEAGVKYLISEYKGVKRELEEICGYEIEEAKI
                     HESIEVYNEHRKTMRDFVEVAYKHSNTIKPSIRSLVIKSGFFMRKEEHTELVKDLIAK
                     LNAMPEEVCSGKKVLLTGILADSKDILDILEDNNISVVADDLAQETRQFRTDVPAGDD
                     ALERLARQWSNIEGCSLAYDPKKKRGSLIVDEVKKKDIDGVIFCMMKFCDPEEYDYPL
                     VRKDIEDSGIPTLYVEIDQQTQNNEQARTRIQTFAEMMSLA"
     gene            complement(14056..15282)
                     /gene="hadB"
                     /locus_tag="PC512_001223"
     CDS             complement(14056..15282)
                     /gene="hadB"
                     /locus_tag="PC512_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(R)-2-hydroxyisocaproyl-CoA dehydratase subunit
                     HadB"
                     /protein_id="HDF2440988.1"
                     /translation="MSEKKEARVVINDLLAEQYANAFKAKEEGRPVGWSTSVFPQELA
                     EVFDLNVLYPENQAAGVAAKKGSLELCEIAESKGYSIDLCAYARTNFGLLENGGCEAL
                     DMPAPDFLLCCNNICNQVIKWYENISRELDIPLIMIDTTFNNEDEVTQSRIDYIKAQF
                     EEAIKQLEIISGKKFDPKKFEEVMKISAENGRLWKYSMSLPADSSPSPMNGFDLFTYM
                     AVIVCARGKKETTEAFKLLIEELEDNMKTGKSSFRGEEKYRIMMEGIPCWPYIGYKMK
                     TLAKFGVNMTGSVYPHAWALQYEVNDLDGMAVAYSTMFNNVNLDRMTKYRVDSLVEGK
                     CDGAFYHMNRSCKLMSLIQYEMQRRAAEETGLPYAGFDGDQADPRAFTNAQFETRIQG
                     LVEVMEERKKLNRGEI"
     gene            complement(15297..16097)
                     /gene="hadI"
                     /locus_tag="PC512_001224"
     CDS             complement(15297..16097)
                     /gene="hadI"
                     /locus_tag="PC512_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyisocaproyl-CoA dehydratase activator
                     HadI"
                     /protein_id="HDF2440989.1"
                     /translation="MYTMGLDIGSTASKGVILKNGEDIVASETISSGTGTTGPSRVLE
                     KLYGKTGLAREDIKKVVVTGYGRMNYSDADKQISELSCHARGVNFIIPETRTIIDIGG
                     QDAKVLKLDNNGRLLNFLMNDKCAAGTGRFLDVMAKIIEVDVSELGSISMNSQNEVSI
                     SSTCTVFAESEVISHLSENAKIEDIVAGIHTSVAKRVSSLVKRIGVQRNVVMVGGVAR
                     NSGIVRAMAREINTEIIVPDIPQLTGALGAALYAFDEAKESQKEVKNI"
     gene            complement(16136..17335)
                     /gene="hadA"
                     /locus_tag="PC512_001225"
     CDS             complement(16136..17335)
                     /gene="hadA"
                     /locus_tag="PC512_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocaprenoyl-CoA:2-hydroxyisocaproate
                     CoA-transferase HadA"
                     /protein_id="HDF2440990.1"
                     /translation="MLLEGVKVVELSSFIAAPCCAKMLGDWGAEVIKIEPIEGDGIRV
                     MGGTFKSPASDDENPMFELENGNKKGVSINVKSKEGVEILHKLLSEADIFVTNVRVQA
                     LEKMGIAYDQIKDKYPGLIFSQILGYGEKGPLKDKPGFDYTAYFARGGVSQSVMEKGT
                     SPANTAAGFGDHYAGLALAAGSLAALHKKAQTGKGERVTVSLFHTAIYGMGTMITTAQ
                     YGNEMPLSRENPNSPLMTTYKCKDGRWIQLALIQYNKWLGKFCKVINREYILEDDRYN
                     NIDSMVNHVEDLVKIVGEAMLEKTLDEWSALLEEADLPFEKIQSCEDLLDDEQAWAND
                     FLFKKTYDSGNTGVLVNTPVMFRNEGIKEYTPAPKVGQHTVEVLKSLGYDEEKINNFK
                     DSKVVRY"
     gene            18012..19010
                     /locus_tag="PC512_001226"
     CDS             18012..19010
                     /locus_tag="PC512_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-2-hydroxyacid dehydrogenase"
                     /protein_id="HDF2440991.1"
                     /translation="MKILVFGARDYEEPVIKKWSEEHKDVQVDIYPENMTEENVVKAK
                     GYDGISIQQTNYIDNPYIYETLKDAGVKVIASRTAGVDMIHFDLVNENGLIVTNVPSY
                     SPNAIAELAVTQAMNLLRKTPLVKKKVCEGDYRWIAELLGTEVRSITVGVIGTGKIGA
                     TSAKLFKGLGANVIAFDQYPNSDLNDILTYKDSLEDLLKEADLITLHTPLLEGTKHMI
                     NKDTLAIMKDGAYIVNTGRGGLINTGDLIEALESGKIRAAALDTFETEGLFLNKKMNP
                     GELTDPEINKLLSMEQVIFTHHLGFFTSTAIENIVYSSLSSAVEVIKTGTATNRVN"
     gene            19372..19899
                     /locus_tag="PC512_001227"
     CDS             19372..19899
                     /locus_tag="PC512_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04002 family protein"
                     /protein_id="HDF2440992.1"
                     /translation="MEKMNKVTSKKTTYIVTSALFASIICLTIAYILHIPVGGNNGYV
                     HIGDAFIYLAATILPTNYAIAASAIGAGLADLSTGAAIWVIPTIIIKPILVLFFTSKS
                     DKIINKRNIVASVVAGIVGLVLYMFAEGIIIGSFTSAFVMSLLGLLQPIGSFIVFIIL
                     GMALDKLDFKKRYFN"
     gene            19926..20522
                     /locus_tag="PC512_001228"
     CDS             19926..20522
                     /locus_tag="PC512_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04100 family radical SAM protein"
                     /protein_id="HDF2440993.1"
                     /translation="MNILYTIENSIYVNITNTCPCSCVFCIRNEKDEVANSGSLWLEH
                     EPSVDEVKEAFNKYNLDDYDEIVFCGYGEPLMRINELIEVAKFIKEKSSIKIRINTNG
                     LSDLIHNKKTAILLKNVIDAVSISLNAPNKEAYNRVTQPKFGEKSFDYMLDFARDCKK
                     YIKEVAFSVVDEISPEEIEESKQLAKKLDIPLRVRHKN"
     gene            complement(20587..22170)
                     /gene="asnB"
                     /locus_tag="PC512_001229"
     CDS             complement(20587..22170)
                     /gene="asnB"
                     /locus_tag="PC512_001229"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HDF2440994.1"
                     /translation="MINLEEKYLTRKDTYMIKILEYNGHIRNWKVLCEELGIDSSLCR
                     DERERAILVEAYKTWGYDMANHMHGMFAFALWDTVEKKLFCLRDQFGVKPFYYYETEN
                     GKLLYGSSIRKIMEQPGFVKELNEDMLQIYMSFTYVAGENTFFRGVKKLMPGHYLVYQ
                     NKTVCIGRYWKPEFHPDHSKSIEEWTDEIHTTLQKIMPEVKSENETAELFLSGGVDSS
                     YILAMSDIEKTGSCGYEEERFDESKLAQQTANILGCKNSRYIITPEEYFASVPYVMYH
                     MEQPTGDASAIVFAIGCKAAAENTNICYSGEGADEFFGGYNIYHKAECYGENLKTFYI
                     GNTNIMNEGEKRKILKKYNPDVLPIEVVKGIYEETEELDTLTNMSNVDIQIWLEGDIY
                     FNIDKMSTAVGLEVRMPLTDTRIFDIASRIPSEYKVKGKENKIAFRTAASKTLPEEIA
                     FRNKLGFIVPIRIWMADDQYNKDIRDKFNSEIADKFFNIDEINEIFNDYISGNSDNWR
                     KIWMIYTFLVWYEIYFVKC"
     gene            complement(22736..23572)
                     /locus_tag="PC512_001230"
     CDS             complement(22736..23572)
                     /locus_tag="PC512_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF2440995.1"
                     /translation="MNYIIKKVLNSSVVLVHDTKDNEFILLGKGIGYGKKTGEYICGS
                     NDNQMFVPVENTKSKQFLELMDDIPVDILKITQEIIVEAEKLLNSSFNKNLYLILADH
                     FNFAIERMRKGIKITNRVFWEIKNYYPNEFKVGMVAIYMVEERLGIQLPEEEAANIAF
                     HFANAMASDGNSYDTIKYAKVIGEIINIFVFSLNRTLDKKSMHYMRFITHIKFFVERF
                     FSDSMLSSGDDLLFNQMKRSNPKEMLIALKVRDFLEKKYGKKLTNEEIAFLVVHIARV
                     KQ"
     gene            complement(23596..25062)
                     /locus_tag="PC512_001231"
     CDS             complement(23596..25062)
                     /locus_tag="PC512_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000110363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HDF2440996.1"
                     /translation="MRKFPEGFLWGGATAANQFEGGWNLGGKGWSVSDVAKAHFDADV
                     KDYKSNNEITTKDIEEGLAHPEDEVNYPKRHGSDFYHHYKEDIALMAEMGFKTYRMSI
                     AWSRIFPNGDDKEPNEEGLQFYDDVFDELISYGIEPLVTMSHYEPPLNIVLNYDGWYS
                     RQVINMFVRYVETICERYKNKVKYWLTFNEVDSMIRHPYTTGGLVRDRFKDKNFEEVI
                     FQAMHHQFVASALATKICHEIIPNSKVGCMLTKLTYYPYTCRPEDVLATQRKMRSIYA
                     YSDTQVFGEYPVYLLSYFKNNNIQIVKEEHDDEIMKKYPVDFISFSYYMSSCEAADTT
                     GLDITPGNTLLAVKNPYLEMSEWGWQIDSIGLRISLIELYDRYRKPLFIVENGLGAKD
                     ILTEDKKVHDQYRINYLKEHFKCMLDAIIEDGVELWGYTSWGCIDLVSESTKQMSKRY
                     GYIYVDADDYGKGTYNRYKKDSFYWYKKVIESNSIDFK"
     gene            complement(25065..26927)
                     /locus_tag="PC512_001232"
     CDS             complement(25065..26927)
                     /locus_tag="PC512_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2440997.1"
                     /translation="MNYKKTAIDIIEQVGGSKNILALEHCSTRLRFKLIDRSKVNQDA
                     LKKVQGVMSIVNGAQFQVVIGNSVVDVYDEILKVCPLDTNDSTVKTEEKINLGTRFIE
                     FIINIFQPLIFAIAGAGILKSLLMLLAMFNILKSDSTIYTLLVAISDATFYFLPLMVA
                     VTTANVLKCNRLVAIAAVGYLLLPATTTALSEGVELFGFTIPNIAYNAQVFPAILCVS
                     FLATMEKIFNKYSPKPIRTFFVPMMSLAITVPITLTILGPLGYNVGTIFTTIILFLYN
                     KMGFLVVGLLAAFLPFMVATGMHKALIPYSINTIGKLGYEALYMTSSLAHNISESGAC
                     FAVALRTKDETLKQTALSAGISALMGITEPALYGITLQHKRAMLGVVFSSAISGTFLG
                     LFAVKGFVIVGPGLASMSMFIDPNNGNNLIFASIGFVIAILGSFIITLIIWKEDTNTV
                     ESSIGDVVEEELEEEKEVNILVTPVEGKVIDLSKVNDELFASKTLGDGVAIIPTNGNL
                     YAPCDSEVVMLFETKHAIGLRTKNGAEILIHIGINTVSMNGDGFKTFVKTGDNVKEGD
                     LLIQFDLDKISHANLDSTVMIVNNNGADYAYKVLNQSYGNVKKGSILFDVKGGI"
     gene            complement(27174..28037)
                     /locus_tag="PC512_001233"
     CDS             complement(27174..28037)
                     /locus_tag="PC512_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HDF2440998.1"
                     /translation="MILSYFALLIRVVLLAFERVVVRLLGDEEGDIYKNIASSFLFFF
                     IGGVCLLPFSIMDRVSDWSFLIPCYISSLVYSIGSVAYVTSLATGEVSLVTPINSLNS
                     LFLLLLSVIFLGEGLSLAKVAGIIIMIGGVFILKKVSSFLKNVSVIFNNLPCRLMFLY
                     IFLQSVGRVLDKAFFVQVSPILYSTILYFFVGLNLFIFLAFKKKQKIICEIFSNKKGL
                     SILSGAINGYSYLALLIALNNLELSIAEPFSQVSMIITLILAHFIFKENIKEKIPGSI
                     LILIGGWLLLL"
     gene            complement(28092..29024)
                     /locus_tag="PC512_001234"
     CDS             complement(28092..29024)
                     /locus_tag="PC512_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HDF2440999.1"
                     /translation="MNNKKAVFFFCSDLKKDPVASNVIKCCEEIMDLNQTDIVIDDNF
                     VLEFKDKNNNLFHFVKTKDVISHNYKYYLPILNRHFRDYDFAGVVNWHEGENAPEHIL
                     TAHTIGDVPTGEFGNSNPRYFKNLINAIEDIKNENLLDEFTTLTEATHWSGTTYGEES
                     KLITEYSVPMLDIEIGSSSDSFNNSIAIQVLAKSLIRVFDCDEPLKTLLCVGGVHFEK
                     SFSDIIKNKEYNISIGHVLPNQWIVSGMYDDESGFEKLEKCINSIEGGIDCIVFHDKL
                     KGTYKEQCRKLGEKLNVPVFKHKILKNPKDLPIW"
     gene            complement(29110..29661)
                     /locus_tag="PC512_001235"
     CDS             complement(29110..29661)
                     /locus_tag="PC512_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2441000.1"
                     /translation="MQSLNEIIAENLKKIRKEKHLSLDKIAQLSGVSKSMLSQIEKCE
                     VNPTISTLKKITNGLKISFTSLMERQESDIELIQKSDIDHFIEDNGKYISYPIFPFDS
                     KRRFEIFMIEIEEGGNLDSNAELPGTQEFITVFSGEVTIKINGEDYIVSSGNSIRFKA
                     DVSHIYRNSGKGIAKMSMVVYYI"
     gene            complement(29890..30381)
                     /locus_tag="PC512_001236"
     CDS             complement(29890..30381)
                     /locus_tag="PC512_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441001.1"
                     /translation="MIDLKIENRKGKIHVKSSEIKDILELRPDFEYVQDISNTINQEN
                     ILVFDCQLTGNSFDMDDLDIEEILEELGEEIDESYFSVLFEDVRAYLKDATDEIEADL
                     QDNYLFDNLRCYFDIYNINQEFTDFKFVFLVSFKDIKISSLANLAKIVSKRQLIGASK
                     FYS"
     gene            complement(30409..30969)
                     /locus_tag="PC512_001237"
     CDS             complement(30409..30969)
                     /locus_tag="PC512_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HDF2441002.1"
                     /translation="MNKLNICIDIDGTITSPYHFLPYLNDIFNKNITEAECITHNWEE
                     LYGSGIRDVYAEFNNKYIHSYDEAKIVEGATEVISTLSKGHNLSFVTARHECLTDVTK
                     NWLSRQGFSDIDVYLLGSDYKVEKARELSCDIFIEDNPLNSVQLADDGVKVILLDTNY
                     NKDVKHQNIVRVSNWIDIEKIIKQGI"
     gene            complement(31121..32278)
                     /locus_tag="PC512_001238"
     CDS             complement(31121..32278)
                     /locus_tag="PC512_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HDF2441003.1"
                     /translation="MNKQSIGKLNMFFMGITQRNLDNRDFFIELEVIFKSGRKEFKGI
                     AIEEDNKYKFNFKGKSDLYTFNELLKNISKEAENYDGLVFKYVERGTIVVIEGDNKKV
                     NVKYLDNKEEVPKIDEFTASQIKNRDYYVKVGQANALLKEIGVLTKDGKIKNDKIRKY
                     NQIDHFVELIDSILKEIKDKDCITILDCACGKSYLSFVLNFYIKEVLKKNCYFIGIDY
                     SDVVIEASKNMAKNLGYKNMSFIKEDLTNYTPNRDVDLVISLHACDTATDMAIGLGIR
                     AKSEAIVVVPCCHKELLGQYRYEAMEPILKHGVFKARFADLITDGLRTLLLEGNGYDT
                     SVVEYISPLDTPKNLMIRAIKTKTNNDKALKEYKELKSQFGVEPTLEKLIY"
     gene            complement(32315..33256)
                     /locus_tag="PC512_001239"
     CDS             complement(32315..33256)
                     /locus_tag="PC512_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441004.1"
                     /translation="MRWILVFIFLYLIPLVVIFRNYKNFKRSCIYSSIYVVLATTIMI
                     SNIYMSGLNKIKESMYYHNYISDETYDEKYVSNFKEKESTDLNQDNKKNEEISNNKNL
                     NNKQDRNIQNKESNEEGSNDIKEKNNSDSNVSVNNKSEKQEDNTKENNKYTSKEKNSE
                     DIKKIDMESIGIFKKEIYNIERAALVPMRECIPYTKDIAKNITKLSSIKKDVTNARNK
                     CKEVVKEYENMQIPELSKEKYTETLSNARDDVKKAYELREKSMESALKLINTKSPKYI
                     GKITEYLDLSDKQIESFKNRLNDLKEEINNSETNNIN"
     gene            complement(33343..34035)
                     /locus_tag="PC512_001240"
     CDS             complement(33343..34035)
                     /locus_tag="PC512_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDF2441005.1"
                     /translation="MSLYAIGDLHFSTSVNKPMNIFGSNWDGHEKKIIDNWKEVVKEE
                     DMVLVLGDTSWGINLSEAKKDLDIISKLPGQKILIKGNHDYWWTTVTSLNKLYEDMRF
                     IQTNFYEYKDYAICGGRGWICPNDVKFDETDEKVYKREEHRLRLSLESARKSGHSKII
                     VITHYPPTNDKLEESLFTKLFEEYNVEKVIYGHLHGKESFKMGLKGIRNGVEYTLASC
                     DYTEFNLIKVHD"
     gene            complement(34144..34956)
                     /locus_tag="PC512_001241"
     CDS             complement(34144..34956)
                     /locus_tag="PC512_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HDF2441006.1"
                     /translation="MEYEKWNEILAPYEHAVEELKIKFKNIRKEYLAKGEYSPIEFVT
                     GRTKKISSIISKLKRINAKDIETEIDDIAGIRIMCQFVEDIYAIVDLIKVRNDMTIIG
                     EKDYITNYKDSGYRSYHVIIKYPINSIAGSKEIICEIQIRTLAMNFWATIEHSLKYKY
                     DHYIPETLAERLRRASDAAFLLDQEMSEIREDIMKAQAMYQMKSIAIRDTLNRIQELY
                     DLGDTHKAMQYQRKLDRTETDKNITEILELKQEIDILLEQYKDTKVDDKVVQ"
     gene            complement(35007..35918)
                     /locus_tag="PC512_001242"
     CDS             complement(35007..35918)
                     /locus_tag="PC512_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2441007.1"
                     /translation="MNLTKVKGNTFFIKGGTNTGIYVFEDNTALMIDPGLCGSRPRRV
                     NKVLDENNIQVRYIINTHGHDDHYGACNQFKEYYKDVCIMSSEYDKLYIENPELFSKY
                     IVGGKSNVFMDNILKNKMLDDIKIDKFIEAGKFELNNEMFDIIEFQGHTPGSIAVLTK
                     DNVIFVGDLLIGDEILSKYDFLFLYDIQEQINSLEKLKNIDFEYLVLGHGKQVISKED
                     SYKLIEKHLNALKKYLYQIRELLVEPKSLEILLKNIINNNNLSNNYKEYHFFKSSLVS
                     VISYLVDLEEIGYILENGELLYYTKTK"
     gene            complement(35977..36708)
                     /locus_tag="PC512_001243"
     CDS             complement(35977..36708)
                     /locus_tag="PC512_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HDF2441008.1"
                     /translation="MTSIKNKDILNCIDYSIKNKLFDKLNDVYKSLPVGNCSGCGNCC
                     MESVGINLIEFLNIFCYLEDRVDLKKSCISKILDYYFEEYTRKNPCPFKDTNNRCLIY
                     EVRPLNCRMFGHWKKEDYNKNLDNVIEKNNNYRELMKKQYGFEINDEVVNYRIDYCDR
                     FIPNKDYLSKSKRLSFFDELMILDSNIYSSGNIDIDFRDRGIVEYFIESLLYRNLAYN
                     VKIRISKEYKIRKRTIDRIKRIVLV"
     gene            36797..37048
                     /locus_tag="PC512_001244"
     CDS             36797..37048
                     /locus_tag="PC512_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441009.1"
                     /translation="MNRYTKIINMMGSYYTKDFEKEKKNVIKVREVKEDTVRKFFLQG
                     DCEVLVVFEDTGKEILIDDFSPEEDIKKYLGAKFINKKR"
     gene            37282..37701
                     /locus_tag="PC512_001245"
     CDS             37282..37701
                     /locus_tag="PC512_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441010.1"
                     /translation="MQIYFRVKAVGKRKPMLELTPFDVSDNINCLKEAISEIVSKNVL
                     EYNEKIPEKSIINFLTNEEIESQADIGKVGFGSIYNENKQSVEKAIEVALQAFEDGIY
                     KVLINEDVIEKLDSSINLKSGDIFTFIRLTLLAGRMF"
     gene            37726..42783
                     /locus_tag="PC512_001246"
     CDS             37726..42783
                     /locus_tag="PC512_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4132 domain-containing protein"
                     /protein_id="HDF2441011.1"
                     /translation="MLERTRVEKNPKIIENFKNNFTKSSSKQYYDLAKSLWDCIENSS
                     YYYREPEDKFLNMIKKYYNCHYYEIKNMDELLSGPLKNALELIFTSEQVEELCQLIKR
                     KMDYTYSGGYYRKGYRSNKLVDYFRGIIRFISNYVDLIYYDFSVIDYLTLPNKVLYYD
                     SIMSDKIALEIDKGNQKVISALEEVIFGENQTALLTRQMIIGIMKSHSDKCYEMLSKL
                     LLAAKQQEGLRQQIVESLDEGTISASIYMLKTILDNNLERFSSVIRALDTWTGLGFSD
                     QKPGIIRKCLELSYKSLTDEKFRIESINSNDNLEIYFALWATATYNIYDSYSLIENLL
                     SCQEKYKKLVALYFLSHTESTYFKHSIASKNIKGDDLEILAWVITNFYVEGSVGYYYS
                     WQNRETNFDLSNTPIDKDFDARKEQFESLKHTLEILNSKTKSFSGSVFPWTWIEISSH
                     EILKCMMTLTAYDMNAQFIDVLMENCHLMSSDLRASLIVNFVNEPKTDRQREFLLECL
                     SDKSVSNRETVLSLLRKLELTDVELDKITNLLSLKTSSIRQTVIKILLEQDDSNLENI
                     ASSLIKSSNSQKCLGGLEIVNLLKDNTARQELYNKLVLLIEDIDKSKKNTSQVQILID
                     NLLGKAKNDYCKENGFGIYNPENKVQIPEQFDFKDDSNSSSKLNKIISNISLSTREDS
                     VSVATKKEAKKILDTDINKIIKVYEKFDELITENADYEYEVERWSGNVDKVLLGYSTY
                     NLTPIKYKVSNDTLDNYPLAELWRETSKKLDLDYKLILDILFYSISTCGYNETEKSWF
                     SSIYSNVLDSKKQNKIYTKLEKLKFNGLTRKLLRVLLNEFDHKEIFNYCLEIYYKLRN
                     LLTIEQCKKQRVEFTKNYYRQNEYCPALNAPILNYWLDKAHSFIYDDISFTKFFYTTF
                     SNYQLLEYKFPFYTSINVFARAHELGLMTEEQVNREMISGYNASNIIRTLTNPRWAGD
                     TLEKYPWLKDNLKTVTNRIIEIESRRGDMPTEVSHLANNIQYFEGINYFVNILVALGK
                     ETFQRGYSYGSNYSKKDVLSSLLKNCYPTKEDDSKKLKSLLKNTDITELRLIESAMYA
                     PQWVNIIEKYLNWKGLKSTIWYFHAHINEGFSAQKESEVALFSPISPRSFIDGAFDVD
                     WFLDSYKTIGEERFNILYKSAKYITSGGNSHRRAQLYADATLGKLDKDMLMKEIETNR
                     NQDKLRSFSLLPMKKGDLKEATFRYEFIQKFAKESKQFGAQRRESESKACTIALENLA
                     RSAGFGDVNRMMWALETEKLNEVAHLFKPKDIDGTSIWIDVDENGKASTKVQKGNKSL
                     KSIPKAIAKHPYVLELKSVQKDLKSQYSRAKQSLEQAMKNEIVFTVKEIANIYKNPVI
                     CPLIKNLVWVCDDNIGYVYNDKSKFFICNIEGETYKLTAKNKLKLAHPVHLFESGKWS
                     EFQHDLFSKQIVQPFKQVFREYYRINSDELSEKTISRRYAGHQIQPKKTVALLRNQLW
                     TVDYEEGLQKVFYKENIVAKMFALADWFSPADIEPPTIETVEFFDRKTYKSLELASIP
                     PILFSEVMRDIDLVVSVAHAGGVDPETSHSTVEMRIAIAKELLLLLKINNVNFEGSHA
                     LIAGNLGEYSVHMGSGIVHKKGMGALNILPIHSQSRGKIFLPFADEDPKTAEIMSKIL
                     LLAEDSKIKDPSILSNL"
     gene            complement(42969..43706)
                     /locus_tag="PC512_001247"
     CDS             complement(42969..43706)
                     /locus_tag="PC512_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2441012.1"
                     /translation="MIKVLICDDDKIVRDDIANIAKESGYVDYVKKVKDGIEAIEFIK
                     NEKIDLLIIDIDMPYKNGIDSAEEILSIDKDIHIVFVTGFADYSLESFKVHPIDFVVK
                     PFKKEKILDSINIAIDHINSHKIANNNFIEDTLFVYKIRKQIHMINFDDIVMFEKNSR
                     AINLHTKDEDIIKFYENFDDLKKRLPPNFFMTHRQYIVNLRFIHKVIPINKSSLEIRF
                     INFQENAILNKSLEKDFLYRFYRVKRF"
     gene            complement(43725..44660)
                     /locus_tag="PC512_001248"
     CDS             complement(43725..44660)
                     /locus_tag="PC512_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDF2441013.1"
                     /translation="MANNFVFPIVILTLFIFSNLIMNKYKFYKELDILKRGILTFFIS
                     CFALILFMEGTKYIQLRLGYSFLLEGVLNIILFLVLIILSFYTGFKVIRLINNNNEQE
                     YKLQKLDSKINHKDNIIIKLRSQKHDYLKHLQVVYSLLNTGLDEDAKEYIMNISNSFK
                     SKNSRYGKVSYLDAIASLKYEECLEKDISFDVYIQDFMDNLEIEPNDMSSVLLNIIDN
                     AIESLSTIKKEKKYIRVHAYEDEFQYIIAIKNNGPKIHNVESIFWNGFSTKEGQDRGY
                     GLHLVKNILDKYDYSILVNSDDFLTEFVILIPKYY"
     gene            44868..47444
                     /locus_tag="PC512_001249"
     CDS             44868..47444
                     /locus_tag="PC512_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDF2441014.1"
                     /translation="MKDNLKIVLRYIKSYKARSLAIVVSIILATSLVVGIGTLSRSAQ
                     QADVDRLKRELGTDHVYFKNIKKNQLKSIKSSKDIKNLGITSYYASTDVNEKLPINIL
                     YANKNYLTSHSKLIKGRFPKASNEVVVEKWILNSMGLKPEINQNLTFKLYQKENPETF
                     KVVGILEDRFIEKKKGQCEIFSNLNESELNDFTTYIEFNEGSDINTNIDNIIKNAMLD
                     EKSIGRNSMLIESTMKNGTLDNSSKYVAIAMSLFAGIVIYSIYVISIYQRVQEYGVLR
                     AIGSTNFRIFKLMLYELFILALIAMPIGICIGMGGAQIFNRSVGNIQFEGNINVTPFV
                     IPDKIILLSIACTILIILIISFFTYLKIRRISPIDAIRKTFGADKNVTKVNYLISKLT
                     LNMSVTKSISAKNIFRNKKGFIIIVLSMSIGGIIVIKDNYKYSFLDVQNKSTQEQTYM
                     NADFILSNVYLNEIGNNTSFKDIKGFNDNQIDKIKNIDGIDKVKTASILNTRIEVNKI
                     NRLDYYEAINSTPYYKLNPLFIKNKTTGKYTLKQKLKGYNDEMIKSLEKYLVSGNINL
                     KKMKKENLAIVYVPEISKTQKYTKTFTPGEGTPAVDIKVGDTIKVKYPKGGMDTGLYE
                     SLKDNYEYLEYEFKVGAIISYPFADNGMYSGDDGVDVITSSEYLKKLTGVDKYNLVYA
                     DLNENANKKKINNLLGKIGSEVPGTTTVDMMVEKENSDKMTSRTMIYSYGIVAIMFII
                     SVLNIINNISYNLTSRTSEFGMLRAIGISERGFKNMILYEGILYGVLSSIITIVSGII
                     IQFKMYYMQGFVSYGLGFSIDYKIYILVILANIIVGILATYIPSRKINKISIVEAINI
                     TE"
     gene            47456..48127
                     /locus_tag="PC512_001250"
     CDS             47456..48127
                     /locus_tag="PC512_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2441015.1"
                     /translation="MPILETINLGKIYGKKETSVHALKNANLKINKGEFVAIIGPSGS
                     GKSTFLHLVGGLERPSNGTIKVDGKDICCLSDKELARYRRQKVGFVFQQYNLIPVLNV
                     KENIELPLKLDNKKIDKEYIDDLINLLGLNERKNHLPNQLSGGQQQRVAIARALSAKP
                     SIILADEPTGNLDSKTTEEVMDLLKSSIKKYNQTLIIITHNENIARKADRIISIIDGE
                     LKLTL"
     gene            48154..48495
                     /locus_tag="PC512_001251"
     CDS             48154..48495
                     /locus_tag="PC512_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441016.1"
                     /translation="MLLILGNLNLNLDFDYRIIREENDDVDIFIDINYRSLDIDTDGS
                     NLFNSRIQFPFVRALILRLNKNNQCMTIHLLRDIDLFSAFANFEVDYTDSIINIKNQN
                     EKVILNKSIKK"
     gene            complement(48855..51497)
                     /gene="adhE"
                     /locus_tag="PC512_001252"
                     /gene_synonym="adhC"
     CDS             complement(48855..51497)
                     /gene="adhE"
                     /locus_tag="PC512_001252"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HDF2441017.1"
                     /translation="MEKKEKVVEKSNVEVCSPEIVNSVETLRMRLEEIRLAQKEFATF
                     TQEQVDKIFLAASTAANQQRIPLAKMAVEETGMGIVEDKVIKNHFASEYIYNAYKDTK
                     TCGVIEKDEAFGFTRIAEPVGVLSAVIPTTNPTSTAIFKSLIALKTRNGIIFSPHPRA
                     KNCTIEAARVVHDAAVKAGAPKGLIGWVDVPSIELTNVVMAEADLILATGGPGMVKSA
                     YSSGKPAVGVGPGNVPAIIDESADIKMAVSSILVSKSFDNGMICASEQAVIVPEKIYE
                     EVKKEFKYRGAHFLNKEETEKVGKVVIIDGSLNARIVGQPAHVIAKMADVEVPKTARI
                     IIGEVESVELNEPFAHEKLSPVLAMYKSKSFEDAVAKAEKLVADGGYGHTSSLYADSI
                     NHPERVEKFVNAMKTCRVLVNTPSSQGGIGDLYNFKLAPSLTLGCGSWGGNSVSENVG
                     VKHLLNIKTVAERRENMLWFRAPEKVYFKKGCLGVAAREFKDVMDKKKAFIVTDSFLY
                     NNGYTKKLTDLLDEMGIKHTTFFDVAPDPTLACAREGAKAMADFQPDLIIAVGGGSAM
                     DAGKIMWVMYEHPEVDFQDLAMRFMDIRKRVYVFPKMGEKAYFAAIPTSAGTGSEVTP
                     FAVITDQDSGVKYPLADYELMPNMAIIDADMMMEMPPRLTAASGVDALTHALEAYVSM
                     LRTEPADGLALQAGKIIFEYLPRAYKNGKNDKEAREKMAMASTMAGMSFANAFLGICH
                     SLAHKLGAFHHVQHGVANALLINEVIKFNCAEAPNKMGAFSQYRYPDCIQRYAEFASF
                     AGIKGSTDQEKVDNLIKAIDELKAKVGLPKTIKEAGVEESKFLERLDAMVEQAFDDQC
                     TGANPRYPLMSELKEIYLKVYYGK"
BASE COUNT        17308 a         8775 c         6203 g        19701 t
ORIGIN      
        1 ttagtcatct tcttaccagt tttttatcca cttttctaat gaagttattt tttcatatgt
       61 taattcctct tgaaataatg atactaaaag actttttata aaattataac ttaaaagttt
      121 atgtattttt ttgatatgaa tttatagtac ttatcttctt taattgagat tgtgtatatt
      181 taactaaaca ttacaacaat aattctatga aatcaaatca attatttaca tattttttta
      241 gaacaataat aagtatatat tcacaaaatt ttgtgttaat atttttaatt tgtgatataa
      301 taaaagcaag gaaacatatt ttacttaact ttgagtgatg tttccttcaa caaattattt
      361 tgaagattta cttttctgga actttatatt aagttcccag ccactcttag ttggtcgctc
      421 agagtggctc tttaatttat cgtaaatgta actggctata acaccagtta taatactcat
      481 cattagattt tccatagttt tcacctcctc tcataagaaa gtgaagaaac ttccatggaa
      541 acaccactca tagctttttc aaatatttat tccttgccat attaattata tcataaatat
      601 tggaaacata aaattttaat acttatcgtc tttattatta ttttttataa ttaataattt
      661 tttttaataa tacataatat aaatttatat ttcttcaata aaaaagacaa tcttaattaa
      721 ttgtcttttt taatatatat ttggctaata cattatttta cacaaacatt acaagggtct
      781 attttacctt gtgacttagc ttgttttaat gttactttat ttattgtttt acttcttttt
      841 agtgtagaac aattttttgt tagatgatat gattttccat taggagttac atatactgta
      901 cttttatcag ttaatccagg attattagag ctaggctcat tacttggttt gttcgtatta
      961 tttgaattag tatcttttac aatgcctgta tttgaatccc caacattatt agttatattt
     1021 aaacattgtt ttataacaac atcatcaata tttccaatag cagttatttt acttgcattt
     1081 tttaatatac tcttattact tccatttcca actaacacta taggtgtttt ttgtgcaatt
     1141 gtagaaccaa ctaaagaata aactaaatca gtcccacttg ctatgtaaaa ttcttttgag
     1201 ccattataaa atttatttat tatttgttta tttgtatcgt atctatctac tccacctatt
     1261 cttgttgctt tagtttcatt tattaactta tcactaatac tgacttttcc accaattgca
     1321 taagtttcta atccatctgt agcaaaactt gtagtgtttc catcagttaa tactattgga
     1381 gatttatctc taactgctat agaagcaaca ctcatagcat ctggttcacc tttaaaagca
     1441 ttagttaata ttactttttt aacagcactt acacttccta tttcttttgc aactttatga
     1501 cttgtatcta ttctatcagt tccacttatt ctatttatgc ttattttttt atcacttaat
     1561 attttctgaa ctgatgctcc tatcgaattt tttcctccga ttagatatac ttcttttacc
     1621 ttttctaatc tttttaatgt ttctgaaggg attgtatctt tcttagttaa caatattggg
     1681 gcatttttag ctcctgacaa tccacttgct gacaatccat cagataatcc attttcagaa
     1741 ttaataagta ttgcaatatc ataattttgt ttatctgcta ttaaacctgc tgtttcatac
     1801 ttatttgtac cttttattga attaatagaa ctaagagcgt ttgatgttgg acaactagca
     1861 atcaataatg aaacagacat ccctattgcc aatagtgttt tgtttaattt cataatgaaa
     1921 tcctcctata aattttataa tattacttaa atattataat tctacataaa agaatatttt
     1981 cctttatgaa attagtttat atttcaaaat tttgtcactt tttaaatcta tatactaaaa
     2041 aatagactat ttgtaacagt ctatttctta gtatatcaaa tatttattta ggtttacgtt
     2101 tctttgtact agtttttgta tatgatattc cagttccagg tatactcaat gtagctgatt
     2161 ttcttccttt tgaattaact gacactctag cacctttaac accagcactt atacctacac
     2221 tcttcttacc taaatttaat ttgagtcctc ctcctagatt tatgcttttc ctaaagttaa
     2281 atcccataga tataaccttc ccttctatat tttaaatatt tatacttaaa attatatttg
     2341 ttatacactt gccatcattg gtatatctag catctatatc tttttacgtt ttttcttctt
     2401 atatactact ccagcaacta cagctgctgt tccagctcca accccataag tagcatttct
     2461 acttttctct tcttctcttt tttctaaacc ttcatcatat acacctttta acttagtttc
     2521 aatagacttc atttcatctg gtatactaaa atcttcttca ttgtaacctt gattatatac
     2581 actttctttt gctttaggta acttaacctt accattatca tatccttctt taaaccaatt
     2641 agcatattta acattaccta tagttgatgt gtcaaatctt tctcctttga tagcactctc
     2701 aaatccttga gtagtgtaat cattttttaa ttgttcttgt atttcgtcat aagcattatt
     2761 ataagcatct ataaatttag aatctatgtt ttcttcaaat gtcatttttt ctttatcttt
     2821 attgctatcc tctatccctt tagctttata ttcttctatc tttttagtct tatattcatt
     2881 gtatccagtt gaatatccgg tatcataagc attttttaaa acttcttttt catatgtatt
     2941 attagattta gcacctgtaa gccctagatt atatccagtc tctttagcct ccttttcttc
     3001 ctcttctaat ttagccttac ctttttcata tccttctgag tactttgatt catatgtatc
     3061 actataatct ccactataat ttgatgaact ataatttcct ttatacccat cttcataccc
     3121 ttgattatat cctttttctc caacagacct cttttgcttt tcttcattat taaccgaagt
     3181 tgctgttcca gaactgcttc ctcctccagt ataaggacaa ccaccattat tatgtaaatg
     3241 agctggataa ccaccacaat gatagtgata acttcctaat ccagatttat ttttattatc
     3301 acgatgacct cctgatgaat cagttcttcc tgaatgagca tacgaaaagc tccctacact
     3361 aatcatagtt atactcattg caacagctat taactttttc ttaaacataa tctatttccc
     3421 cctaaaatat tctatgattt tattatatca gtcaatatat tatgtttaaa ccgttaaaat
     3481 tcgacaatgt aaatatttga tgaattgtat ttgtaaataa atcttttagc atatcttgaa
     3541 tatctgtagt tgttttgaca tcatattctt caataagttt tttaatattt cgtttttgtt
     3601 aaacataaaa agcgtgcact tttctttgta tagtgatatt tgatatttta attatcacta
     3661 ctttagaaga atacacactt tattttaaaa accctgatac tatgttatta gaaaatggta
     3721 ctaatataaa agatatccag catatactcg gacatgctaa aacttcaaca actatggata
     3781 catatttaca tgtaactaac aacatgagaa accagacggt aaatattttt gaaatcattg
     3841 tagaataaat ttgccaccca aaaataatta tggtggcaaa taggtggcaa atctactttt
     3901 aagacacact ataaaagtct gaaaccctgt tattctctaa taagtttaac tacagtctca
     3961 caatgtggcg tatttgggaa catatccata cacttaacca tcttaatctc ataaccatac
     4021 cccttaaaat caaccaaatc aacaaccaaa gacttaggat tacaagaaat ataaacaatc
     4081 tccttagcac caaatccaca aatatcccta atagcatcct tatgaatgcc tggtctagga
     4141 gggtcaacaa taatcaaatc aggcttgtcc tttaaatcct taacaacctt agccacatcc
     4201 ccagcaataa actcacaatt agtaagtcca ttcaacttag cattctcatt agcagcaaca
     4261 acagcttcct caactatctc aataccatac actttcttag cagcaccagc cataacctgt
     4321 ccaatagacc cagtaccact atacaagtca aatacaactt tatcattgta atctccaata
     4381 aaatccctag caatactata aagaacctca gctcccttag tattggtttg gaaaaacgaa
     4441 aatggtgaaa tcttaaactt aagacctaaa atttcttctt gtatataatc tcttccatac
     4501 aatactctta actcatcaca ttggactgca tctgctaaac catcattaat agtatgaagt
     4561 acacctacta actcagcttt taaatcaatc cctaaaagca tatctttaaa ctcatacata
     4621 tcaaaatctt cttgagaaga agttactata ttaactataa tctcattagt gtgaatccct
     4681 tttctaacta caagatgtct caaatatcct ttgtgattca ttgttctata ataaggaagc
     4741 tttttttcat tgaaaaactc tacactagaa actaatatct ttgagaagtc ttcatcaacc
     4801 aacatacact cctcaacagt ttgtatatct atatgctttc cttttttatg aagacctaat
     4861 gtcaaaggtc cattttttac ttcatctcca aaagtatatt ccatcttatt tctataatat
     4921 ttgttttctg gacttccttc tatccctaaa aactgaaatc caaataaatc ttgctttaaa
     4981 aataaatcca taacttgttt ttcttttatt tctaattgtt tttcatatgg cacagacaat
     5041 agtgtacatc ctccacactc tctaaagtgc ttgcaagttt cttcagtttc aagtggtgag
     5101 ttctctaata attctatcat cttaacttca gctttcttac ttctaacttt tttaactcca
     5161 gctctcacct tttgaccact tattccaccc ttcatatgga taactctatc tccaacttgg
     5221 cttaaagatg taccaccaaa ttccatttta tctacttcaa attctataac atcttttttc
     5281 ttcacagaca ttcctccaat ttactatagt atctttatta tctttcttca atcaatttta
     5341 cttcttcatc tgttaactct ctatactcac ctaactctaa actttcatcc aattttaaat
     5401 tgcccataga caatcttttt aagtatacta cttttttgcc tacgctttca aacattcttt
     5461 ttacttggtg aaacttacct tcatgtattg taagctctat ttctgattca tcatcacttt
     5521 ttaatatatt taactgtgat ggcatagttt tatatccgtc atcaagcact acaccttcta
     5581 aaaaagcttc tacatcttct tcagtaacta ctccatcaat ttttgcataa taagtcttag
     5641 gcacatgctt cttaggagat aaaactctat gagaaagctt tccatcatta gttaaaacta
     5701 ataatccctc tgtgtcttta tctaaccttc caacaggaaa tggttcaaaa gctaagtatg
     5761 ataaatcaat taaatctaat actgttgggt catatttatc tgtagttgct gatatatatc
     5821 catcaggttt attcatcatc aaatatatat attctctata tataacttct tctccattaa
     5881 ataatatctc atcattttca gtgtctactt gagttcctgg atttgaaact tcacttccat
     5941 ttactactac agacccttgt ttacaatact tctttatttc acttctgctt ccataaccta
     6001 aatttgaaag aattttatct atacgttgct ttttagccat taaaaatgct ctccattctc
     6061 ataatatttt tctttttcaa atactgtaaa tgctaaatcc atactttcta catctaaatt
     6121 atttcttata ctatcagtta ttattcttgc tactatatct tgtacttctt gtcctctatc
     6181 aaaccaagct acttcaacaa aaggatatac atctgctatt ttaccatctc ttattgcaac
     6241 tgactttata cattctattt caaagtagtc tcttggacat tttacagctt caactaaatc
     6301 atttatcatt ttttcactta ttttacatat atcattttca ttaattcctc ttatttttat
     6361 ctgtggcata gtttatctcc tttattttaa atttttagtg aattatcatc cacttaattc
     6421 ccttcgataa cgtttgaagt ggtaacttct tggtcaagac aactattgtt atcagtatct
     6481 ccaaactaat aaggtagttc ctacccttat agttagcatt atatagctaa ttttcctaaa
     6541 ttgtttatat tctttattat tttatttaat cctattgtct tctatttaac attatacttg
     6601 taatttatag ttattacaat ttactatata ctttttttga tttaacgtta taatataagt
     6661 gatgggtaaa ttttaaaagt taataggagg agtttaaaat ggcattaatt actacaaaag
     6721 aaatgtttaa aaaagcttac gaaggtggat ttgctatagg tgcatttaac ataagtgact
     6781 tagaacaatt acaaggtgtt ttaaaagctg ctaaagctaa aaattcttat gttatgatac
     6841 aagcttctat gtcagctgtt aaatatgctg gacctcatac attagttgaa atggttaagg
     6901 ctgcttctga tgaaataggt gtagatgtag ctcttcactt agaccatggt ccaaatatgg
     6961 atgctattaa aacttgtatt gatgctggtt tctcttcagt tatgatagat ggttctcatt
     7021 ttgactttga agaaaatgtt agaataacta aagaagctgt tgaatatgca cactctaaag
     7081 gtgttgttgt tgaagcagaa cttggtgttc tagctggaac agaagatgat gttacttctg
     7141 atgttcacaa gtatactcaa ccagctgagg cagttgagtt cgttgaaaga acaggtgttg
     7201 attcattagc aatagctatt ggaacttctc atggtgcttt caaattcaaa ggagaagcta
     7261 aattaagatt cgatatacta gaagaaatcc aaagcaaatt accaggtttc ccaatagttc
     7321 ttcatggtgc atctgctgtt gaccaaaacg ctgttgctac atgtaatgaa tttggtggaa
     7381 atatagctgg tgctaaaggt gtacctgtag atatgttaag aaaagcatct tctatggctg
     7441 tttgtaaaat aaacatggat actgacttaa gactagctat gactgctgct atcagaaaat
     7501 tcttagctga aaatccaaaa gaatttgacc caagaaaata cattggtgct ggtagagatg
     7561 ctatacaagc tgtagttgaa agcaagatag atgatgtttt aggttctgct aactctataa
     7621 actaatataa cttttaaata tttataaaag aaaagagatg acttaaagta attaaattta
     7681 tttttaagcc atctctttta agttgtataa attatgtatc ttataatatt ttaattatat
     7741 tgtcttttta aactgacagc taaacgtgaa tatgtccact ctttatcttt ctatggatgg
     7801 tagaaggata tatacctata acttcagcag cctttgttat tgaaccatac ttatttatag
     7861 ccttacttat cattatttgg tccactattt tatatgcatc attaagattc ataattccat
     7921 ttaccactat tggtgataaa tcatctgttt cattatcaat catatctaaa tttatcagca
     7981 tgttaaattc atcttctcca attacatttt tagctgataa tactacaaat ctttcaatga
     8041 tgttttttaa ttctcttatg tttcctggcc aagaatattc ttctaataac tcaataactt
     8101 taggcgaaac ttctacttct ctattgtact tttcattgta aagttttaag aaataattta
     8161 ctaatggtac tatatcctct tttctttctc taagaggagg tatttttact ggaataacac
     8221 ttaatctata gtacaaatct tgtctaaatt taaggttatt tctaaggtct tcatgagaaa
     8281 tattagtagc acttatatat ctaacatcta tttttatagg cttactacca cctattctag
     8341 taatagtatt ttcttgtata accctaagta attttttttg catctgcatt ggtaactcac
     8401 ctatctcatc caagaaaata gttccaccat tcgcctcttc aaaaagtccc tttttacctt
     8461 ttttcttagc tccagtaaaa gaaccttctt catatccaaa aaactctgac tctaataatt
     8521 catttggtat agctccacag tttatagcta taaagggttt gtctctcctt gaactatact
     8581 tatatattgt tcttgctatt atttcttttc ctacacctga ttctccattt ataaatatag
     8641 aagaatctga ggctgcagct ctcttaacaa ctttttttat attgtccata atcttacttt
     8701 gacttatata ctctgtgtct tctgatatat cactatattt tatctgagat tcaagcttaa
     8761 taacccttga aatatctctc cctgttagta ctcctcctgt aagctttccc ttagaatccc
     8821 atcttggaac tgccgtatat gcaataagct tcccatctgg gtaaacgata tttctataaa
     8881 tctttttctt cactttaagc atgtttaata ttattggttc ttcaactaat ccttgtctca
     8941 caaggtctgt tatatttcta ccaagtacct cagttctttt aaaaggtaat atctcatcac
     9001 tgacagtgtt catcttttca attaccccat ctttgttaaa cacaacaaca acttcatcta
     9061 tatgctctat tatatcttca attactttat cagatattag agacttctca aataaataaa
     9121 ctatattatt ttcattatta ttatctttca tattgtatat atgtgcagtc atccttaact
     9181 ctctgaaagc tattttcttt ttactatctg tcagtatttc tgttttgtca aaatttgaat
     9241 ctaattcatt tatatttcta ggctttttta tatctagaaa actaaaaata ctatctatta
     9301 gatgattaca gtatattatt tcgcctgatt ctttacataa aatggctgga ttttctacat
     9361 gttctataag ccctattaaa ttattatcca ttaatattcg cacctttcat taagtaattt
     9421 attgaactac atacaaaatt tattgtttgc ttacaataaa taccatcagc acatataatc
     9481 aactccttat aatattcgtc ttttcaagta gtttatttca ttaaaacgta actaagatat
     9541 aattttaatg attatagttt gttaaaaatt tcattttgct tttaattgta ttttatcaca
     9601 tatttagtaa ttatttgtct atttaataca atttaattaa atttaagatt tatttaaaaa
     9661 aacaaagata atccttacag aatataactc acaatttgta agcaatatac atataaggat
     9721 tatccagatt atcttgtatt ataaaatttt attcaaacag actttttaat aactgacaaa
     9781 tacacactag caataactta tcaaagggtt aataattatg ttactaacta ataagactta
     9841 ttcaatcagt aatatttata tagtttgtat ctattaagct tttatagctt ctaataaatc
     9901 atcaacgcta tctaattttt ctataagcat tggaactatt tcatgtaagt ctccaactac
     9961 tccatagtca gcgatttcta aaattggagc tgctgggttt ttgtttatag caattatgaa
    10021 atctgatgat tgcatacctg ctaaatgttg tattgctcct gatataccac aagctatata
    10081 taggtttggt ttaacagtag ttcctgtttg acctacttgg tgagaatggt ctatccatcc
    10141 agcatcaaca gccgcacgag aagaaccaac tactccacct aatttgtcag ctaatttctt
    10201 aagcatttca aatccttctg gtccacctaa tcctaaacca cctgatacta taacatttgc
    10261 atctgtaaga gatactaaat ctttcttagt tttaactgtt tctaaaacag tagttcttat
    10321 atcatcttga gttattttgt agtctaatgc tataacttca ccagttcttg tttcgtcttt
    10381 ttcagcttta tccataacac caggtctaac tgtagacatt tgaggtctat ggtttggaca
    10441 aatgattgta gccattatgt ttccaccaaa tgctggacga gtttgtttta ttttcttatc
    10501 ttctgggtct atttctaact tagtacagtc agctgttaat ccagttccaa ctcttgaagc
    10561 tattctaggt gctaagtctc tacctatatg agttgctccg aaaagcatta tttctggttt
    10621 tatttcatct attgcatctt ttattacttt tgtatatgca tcagttgtat atttttctaa
    10681 aagagcatca tctgcaacat aaactttgtc agctccaaaa gtgattaatt ctttagctaa
    10741 tccatcaaca tcttttccta ataatattgc acaaagttct gcatctactt ctttagctaa
    10801 ttttcttcct tctcctaata attctataac tactggagct atttttcctt ctctttgttc
    10861 tgcaaatatc catacgtttt tataagaact taaatctttt atatcattca tagtttgtac
    10921 tcctccaact tatataatgt gcttttgttt tagaccgatt attattttac tagctatttc
    10981 atcagcttta ccttctaaga tttctccttt tcctcttggt tcaggagtaa atgatctaaa
    11041 tactttagtt ggtgatgctt ttaaaccaac ttcttcttta tttacatcta aatcatcaat
    11101 tgtccaaact tttacatcat gtttatatgc ttttactatt ttatcaacag acatgtatct
    11161 aggtgtattt aactctttta ctgctgttaa aagtacaggt gtacttactt ttattaattc
    11221 gtatccatct tctaattgtc tttgaactat tatatctttt ccttctattt tgaaatcttg
    11281 tacatatgta acttgaggaa tgtctaattt ctctgcaatt tgtggtccaa cttgtgcagt
    11341 atctccatct attgcttgtc ttcctgcaaa tattatgtca tagtcaccta ctttagatat
    11401 tcccgctgca atagtatttg atgtagccca agtatcagct cctccaaatg ctctatcact
    11461 taataatatt gcatcatcag cacccatagc taaacactct cttagcataa agtctgcttg
    11521 aggaggtccc attgttataa ctgttatagt tacatcatca tgctcatctt taatttttaa
    11581 agcttcctct aatgcatttg catcatctgg gtttaatata cttggaactc catctcttat
    11641 aagagtacct gtttctttat ttattcttac ttcgttagta tctggaactt gttttacgca
    11701 aactaatatt ttcaaagtct atacctccaa tttcattaga ttatttatta ttttaatacg
    11761 tttgatgaaa ttaccatttt ttgaacttct gatgttcctt cgtatattga tacgattcta
    11821 gcatctctgt acattctttc gatttcataa tcttttataa atccatatcc accgtgaagt
    11881 tgtaatgctt tataagcaac ttcatttgca atttctgatg catagtattt agccatagca
    11941 gattcttgag caactctcat tcctgcatct ctcttttgtg ctgcatcata aactaatcct
    12001 ctagctgcac aaacttttgt ttccatgtca gctatagtaa attgagtatt ttggaattta
    12061 gctataggct taccaaattg aactctttgt tttgtatatt taacagcttc atctaaagca
    12121 ccttgagcta ttcctagagc taaggcagca acacctattc taccaacttc tagagtaccc
    12181 attgctatct taaatccttg accttctttt ccaagtaagt tttcttttgg aactttaacg
    12241 ttttcaaata ttaagtcaga agtttcagtt cctcttatac ccatcttatc ttcatgagct
    12301 cctgttgaga aaccatccca tttactttct actataaacg ctgatgttcc tctaagtcct
    12361 ttacttctat ctgtaactgc tattactata gctacatcac agaatggtcc attagttatg
    12421 aaagtttttc taccatttaa tatatagtgg tctccaacta attctgctgt tgtttgttgt
    12481 ccacctgcat cagaaccagc tcctggctca gttaaaccaa atgctcctat taattcacct
    12541 gttgctatac cttttaagta tttttgtttt tgctcttcag taccattgta aagtattggt
    12601 aatgaagcaa gagaagaacc agctgtaaca aaagtagctg ttgaagcaca tcttctagct
    12661 atttcttcca ttactatagc gtaagaaaca tatcctgctc ccccaccacc atattcttct
    12721 gggatattac tgcttataaa ttttgcatca gctaattttt tgattaattc cttaggcatt
    12781 acacctgttt tatccatttc tgctggtaaa gtatctaatt ctttactaac aaaatctctt
    12841 actgcttttc ttaaaagttc ttgttctttg ttatataaca tagcttcctc caattttcat
    12901 attttatagt aaatttattt taatgaactt acgctaaact catcatctca gcaaaagttt
    12961 gaatacgagt tctggcttgt tcattattct gagtttgttg gtcgatttca acatataaag
    13021 taggtattcc actatcttct atatcttttc taactaaagg ataatcgtat tcttctgggt
    13081 cacagaattt catcatacag aagataacac catctatatc tttcttttta acttcatcta
    13141 ctataagtga cccacgtttt ttcttagggt cataagctaa tgaacatcct tctatgtttg
    13201 accattgtct tgctaatctc tctaacgcat catcacctgc tggtacatct gttctgaatt
    13261 gtcttgtttc ttgtgctaag tcgtcagcta caactgatat attgttgtct tctaaaatgt
    13321 ctaatatatc tttagaatca gctaatatac ctgttaataa aactttcttt ccagaacaga
    13381 cttcttctgg catagcattt aattttgcta ttaaatcttt cactagctca gtatgttctt
    13441 cttttctcat aaagaaccca ctcttaatta ctaagcttct tattgatggt tttatagtat
    13501 tagaatgttt ataagctact tcaacaaagt ctctcatagt ttttctatgt tcattgtaaa
    13561 cttctatact ttcatgaatt tttgcttctt ctatttcata tccacaaatt tcttcaagtt
    13621 ctctttttac acctttgtac tcactgatta agtattttac accagcttca agttttctat
    13681 tttgtgggtg tactaatgat atatatttta tatgaggtac tgctgatttc cagttttgtc
    13741 ctaaacaaat tagtgtatca cacatacctg gtataataac tccagataat tcatcataag
    13801 caccttttaa tccatattct aaacatgatt gcattattga acatgcaaat gcagggaaat
    13861 attgtttagc taaatctaat tctgtttgtc ctccccatat accaactgga agcattccag
    13921 ctgcatgtat aatttcttct gggcaataaa ctgggaaaca acctatagct tttttaccag
    13981 tttcactttt atattttttt acagccgcat ttggattttc aactacttct ttcattttag
    14041 ataaaatagc ttccattata tctcacctct attaagtttt tttctttctt ccattacttc
    14101 aactaaacct tgaattcttg tttcaaattg agcattagtg aaagctctag ggtctgcttg
    14161 gtcaccatca aatccagcat atggtaatcc agtttcttca gctgctcttc tttgcatttc
    14221 atattgtatt aaactcataa gtttacagct tctgttcata tgatagaatg ctccatcaca
    14281 tttaccctct actaaagaat caactctata ttttgtcata cggtctaggt ttacattgtt
    14341 aaacatagta ctatatgcta ctgccattcc atctaaatca ttaacttcat attgtaatgc
    14401 ccaagcatgt gggtaaacac tacctgtcat gttaactcca aatttagcta atgttttcat
    14461 cttgtatcct atatatggcc aacaaggtat accttccatc attattctgt atttttcttc
    14521 ccctctgaaa gaagatttac cagttttcat gttgtcctct aattcttcta taagtaactt
    14581 aaatgcttct gtagtttctt ttttacctct agcacaaact attacagcca tgtaagtaaa
    14641 taagtcaaat ccattcattg gagaaggaga agaatctgct ggtaaactca tagaatactt
    14701 ccatagtctt ccgttttcag ctgatatttt cattacttct tcaaacttct tagggtcaaa
    14761 tttctttcct gatataattt ctagttgttt tatagcttct tcaaattgag ctttaatata
    14821 atctattctt gattgagtaa cttcgtcttc attattgaaa gttgtatcaa tcattattaa
    14881 aggtatatct aattctcttg aaatattttc ataccatttt ataacttggt tacatatatt
    14941 gttacagcaa agtaggaaat ctggagccgg catatccaaa gcttcacatc caccattttc
    15001 taaaagacca aaatttgttc ttgcatatgc acataggtca atagaatatc ctttagattc
    15061 agctatttca cataattcta aagaaccttt tttagctgct actccagctg cttggttttc
    15121 tggatataat acgtttaagt caaatacttc tgctaactct tgaggaaata ctgatgttga
    15181 ccaacctaca ggtcttcctt cttctttagc tttaaatgca tttgcatatt gttcagctaa
    15241 taaatcatta attactactc tagcttcttt tttttcagac attttcatcc ctctttttat
    15301 atatttttca cttctttttg tgattctttt gcttcatcaa aagcatataa cgctgctcct
    15361 aaagcaccag ttaattgagg tatatcaggt acaataattt ctgtgttgat ttctcttgcc
    15421 atagctctta caataccact atttctagca actccaccaa ccataactac atttctttgt
    15481 actcctattc tttttactag gctagaaact ctctttgcta ctgaagtatg aatacctgcc
    15541 actatatctt caatttttgc attttcagat aaatgtgata taacctcaga ctctgcaaat
    15601 actgtacatg tactgcttat tgatacttca ttttgagaat tcatagatat acttccgagt
    15661 tcagatacat caacctctat tatttttgcc attacatcta aaaatcttcc tgtacctgca
    15721 gcacatttgt cattcataag aaagtttaat agtcttccat tattatctaa ttttaatacc
    15781 tttgcatctt gaccacctat gtcaataatg gttcttgtct ctggaattat gaaatttacc
    15841 cctctagcat gacagcttaa ttcacttatt tgcttatcag catctgaata gttcattctt
    15901 ccatatcctg taactacaac ttttttaata tcttctcttg caagacctgt cttgccatat
    15961 aatttttcta aaactcttga tggtccagta gtcccagtac cagaggatat tgtttcagaa
    16021 gctacaatat cttccccatt ctttaagatt actccctttg atgcagttga acctatatct
    16081 aatcccattg tgtacatctt tagcattctc cttttaaaaa atctagaatt actaattaat
    16141 atcttacaac tttactatct ttaaagttat ttattttctc ttcatcgtag cctaaagatt
    16201 ttaatacttc tacagtatgt tgacctactt ttggtgctgg tgtatattct ttaattcctt
    16261 catttctaaa cataactgga gtattaacta agacacctgt atttccgcta tcgtatgttt
    16321 tcttaaataa gaagtcattt gcccaagctt gttcgtcatc taataaatct tcacagcttt
    16381 gaattttttc aaatggtaag tctgcttctt ctaataaagc tgaccactcg tctaatgttt
    16441 tttctaacat agcttctcca actatcttaa ctaaatcttc aacatgatta accattgaat
    16501 ctatgttatt atatctatcg tcttctaata tatattctct atttataacc ttacagaatt
    16561 tgcctaacca cttgttgtat tgtattaaag ctaattgaat ccatcttcca tctttacatt
    16621 tatatgtagt cattaatggg ctgtttggat tttctcttga taaaggcatt tcatttccgt
    16681 attgtgctgt tgttatcatt gttcccattc catatatagc tgtatggaaa agacttactg
    16741 ttactctctc acctttacca gtttgagctt ttttatgtaa tgctgctaaa cttcctgctg
    16801 ctagtgctag acctgcatag tggtcaccaa atcctgctgc tgtatttgct ggagatgttc
    16861 ctttttccat aacagattgg ctaactcctc ctcttgcgaa gtatgcagta tagtcaaatc
    16921 ctggtttatc ttttaaaggt cctttttcac catatcctaa tatttgagag aatattaatc
    16981 ctggatactt atcttttatt tggtcataag ctatacccat tttttctaat gcttgaactc
    17041 taacattagt tacaaatatg tctgcttctg ataataattt atgtaatatt tctactcctt
    17101 cttttgattt tacattaata cttacaccct ttttatttcc attttctaat tcaaacatag
    17161 ggttttcatc atctgatgct ggagatttaa atgttccacc cataactctt attccatcac
    17221 cttctatagg ttcaatctta ataacctctg caccccagtc acctaacatt tttgcacaac
    17281 atggtgctgc gatgaaactt gaaagttcta ctactttaac tccttctaaa agcataacgt
    17341 tttcctcctt aatagtatca attataaaat ttcgattaaa tcactcataa aatacttttt
    17401 tctgatatta actgtctgat gtcaaagttc ctaatcttat ctaaaataac ttaaaaatta
    17461 ttaaaattat tttttattgt tttattgtct tacacctata ttgttaagca tttatcgtgc
    17521 caactttata tttaatcaaa atatcgcttg atttgaatgt tttttaacaa tatgcaattg
    17581 aataatcttt ttcatatcgt ggcatcttgc cactatccat tgcattttgc tattctttct
    17641 atgcttataa aagttttttt tatatatttt tttatgaaaa agcttgacat ttcaaaaaaa
    17701 gttttcattg ctaaactcaa aaacacatgt tatcattgta attaatcagc aagttagtta
    17761 actaatttca aacttagata attttttaat aatatttaat ctaaaaaata acaatttctt
    17821 tgataaattt tagagtaatt attacattaa ataaaaaatt actaaatatc aaaataacac
    17881 agggaaaaca atttcaaaac taaattttta accttaaaaa ttttgtataa aaaatataac
    17941 cttatatgct acatattatt tctaaatgaa aaattaccat aataatttaa taattacagg
    18001 agggtattga tatgaaaata ctagtatttg gagcacgcga ttatgaagaa ccagtaataa
    18061 aaaaatggtc tgaagaacat aaggatgttc aagtggatat ttatcctgaa aacatgactg
    18121 aagaaaatgt agttaaagct aaagggtatg atggtatatc tatacaacaa actaactata
    18181 tagataatcc ttatatttat gaaactttaa aagatgctgg ggttaaagtt atagcttcaa
    18241 gaactgcagg ggttgacatg atacattttg atttagttaa tgaaaatgga cttatcgtta
    18301 caaacgttcc ttcttattca cctaatgcaa tagctgaatt agctgttact caagctatga
    18361 accttttaag aaagactcct ctagtaaaga aaaaagtctg tgaaggtgat taccgttgga
    18421 tagctgaact tcttggaaca gaagttagat ctattacagt tggtgttata ggtacaggaa
    18481 aaataggtgc tacttctgca aaattattca aaggcctagg agctaatgta attgcatttg
    18541 accaatatcc aaatagtgat ttaaatgata tattaactta caaagattct ttagaagacc
    18601 ttctaaaaga agctgacctt ataacattac atactccttt acttgaagga acaaaacata
    18661 tgataaataa agatactcta gctataatga aggatggagc ttacatagta aatactggcc
    18721 gtggtggttt aattaataca ggggatttaa tagaagcact agagtcagga aaaattagag
    18781 ctgctgccct tgatacattt gaaactgaag gattgttctt aaacaaaaaa atgaatcctg
    18841 gagaattaac tgacccagaa ataaataaac ttctttctat ggaacaagtt atattcactc
    18901 atcaccttgg tttcttcact agtacagcga ttgaaaatat agtttattct agtttaagta
    18961 gtgctgtaga agttataaaa acaggaactg ctactaatag agtaaattag tattttataa
    19021 atatattttt tcattaatta gctattatct aacaaaatag cctttaattt cccaaatata
    19081 agagagtcag ctcagtatat attgagtaga ctctcttata ttatttttta tattaaactt
    19141 gtactcttct tattcatacc aaattaaatt tatattaact tactctaact actcctactc
    19201 tatacatttt acctattttt acttttctaa ttatatacat ttgaatgggt acaatctgta
    19261 ttttacaaaa aaaacaccta acaaactatg aaaattgtat gattaatatt aatatattta
    19321 taagaaaaca taacaattat gttagctctg gatttttagg gagggagtat attggaaaaa
    19381 atgaataaag ttacttctaa aaaaactacc tatattgtta cttcagcatt atttgcatcc
    19441 ataatatgcc tgacaatagc atatatatta catattccag ttggtggaaa caatggatat
    19501 gttcatatag gagatgcttt tatttatcta gctgcaacta ttttgccaac aaactatgct
    19561 atagctgctt ctgcaattgg tgctggtcta gctgatttat ctacaggtgc tgctatctgg
    19621 gtaataccaa ctataatcat aaaaccaata cttgtattat ttttcacttc taaaagtgac
    19681 aagataataa ataagagaaa tatagttgct tcggttgtag caggtatagt aggattagtt
    19741 ttatacatgt ttgctgaagg tataattatt ggaagtttta caagtgcatt tgtaatgagc
    19801 ttacttggct tattacagcc aataggaagt tttattgttt ttataatctt aggtatggca
    19861 cttgataaac ttgattttaa aaaacgttat tttaattaag aatttaaatt tatggaggga
    19921 aaattatgaa tatcttatat acaattgaaa atagtatcta tgtaaatata actaatacat
    19981 gtccatgtag ttgtgttttt tgtataagaa acgaaaaaga tgaagttgca aatagtggta
    20041 gtttatggtt ggagcatgag ccaagtgtag atgaagtaaa agaagccttc aataaataca
    20101 atttagacga ctatgatgaa atcgtatttt gtggatatgg cgaaccatta atgagaataa
    20161 atgaattgat agaggtagca aagtttataa aagaaaaaag tagcataaag ataagaataa
    20221 atacaaatgg tctaagtgat ttaatacata acaaaaaaac agctattctg ttaaaaaatg
    20281 ttatagatgc agtatcaata agtcttaatg ccccaaataa agaagcttat aatagagtta
    20341 ctcaaccaaa gtttggagaa aaatcatttg attatatgtt agattttgca agagattgca
    20401 aaaaatatat aaaagaagta gctttttcag tagtagatga aatatctcca gaagaaatag
    20461 aagaatctaa acaactggca aaaaaacttg atataccatt aagggttaga cataagaatt
    20521 agcaagtaaa attataaaac attaagaatc acctgaatgg tctttcaggt gattcttcct
    20581 cttgtattaa cattttacaa aatagatttc ataccacact aggaatgtgt aaatcatcca
    20641 aatctttctc caattatcag agtttccact aatgtagtca ttaaaaatct cattaatctc
    20701 atctatgtta aagaatttat ctgctatctc actattgaat ttatctcgga tatccttatt
    20761 atattggtca tcagccatcc atatacgaat tggcacaata aatcctaatt tatttctaaa
    20821 agcaatctct tctggtaatg tttttgatgc agctgtacga aaggcaattt tattctcttt
    20881 tcctttcact ttatattctg atggtattct ggatgcaata tcaaatattc ttgtatctgt
    20941 aagaggcatt ctgacttcca atcctactgc agtactcatt ttatctatat taaaataaat
    21001 atctccttcc aaccatattt gaatatctac atttgacatg ttagtaagtg tatctagttc
    21061 ttctgtttct tcataaattc cttttaccac ttcaatagga agcacatcag gattgtattt
    21121 cttaagaatt tttcttttct caccctcatt cataatgttt gtatttccaa tataaaatgt
    21181 cttcaaattc tctccataac actctgcctt atggtatata ttatatccac caaaaaactc
    21241 atctgctcct tctccagagt aacagatatt tgtgttttca gctgctgcct tgcatccaat
    21301 agcaaaaacg atagcagatg catctccagt tggttgctcc atatggtaca ttacataagg
    21361 tactgacgca aaatactctt caggtgtaat tatatatctc gaatttttac acccaagaat
    21421 attagctgtc tgttgtgcta attttgattc atcaaaacgc tcttcctcat aaccacatga
    21481 acctgttttt tctatatctg acattgccaa tatataagat gaatcaacac ctcctgatag
    21541 gaataactct gcagtttcat tctctgattt tacctctggc ataattttct gaagtgttgt
    21601 atgaatttca tccgtccatt cctcaataga cttgctgtgg tcaggatgaa attcaggttt
    21661 ccaataacga ccaatacata ctgttttatt ctgatagaca aggtaatgtc ctggcataag
    21721 cttctttact ccacggaaga atgtattttc acctgctaca tatgtgaaag acatataaat
    21781 ctgtaacatg tcttcattta actctttcac aaatcctggt tgctccataa tcttacgaat
    21841 agatgaacca tagagaagct tcccattttc agtctcataa taatagaaag gttttacccc
    21901 aaactggtct cttaggcaga agagtttctt ttccacagta tcccataatg caaaagcaaa
    21961 cattccatgc atgtgatttg ccatatcata tccccatgtc ttatatgctt ccactaaaat
    22021 tgctcgttca cgctcatctc tacataatga agaatcgatt ccaagttctt cacaaagaac
    22081 tttccagttt cgaatatgcc cattgtattc tagaattttt atcatatatg tgtcttttcg
    22141 tgttaaatac ttttcttcta aatttatcat atgtgtatcc tttcgtatta aaacatttaa
    22201 cttctaaatt tattaaatgt ttatatatat ttattcactt ataatcactg aaaaatcgac
    22261 ttttttcaaa gtaaattctt tttgaattag tactaatctg ctctttatta atggcataaa
    22321 tatgattatc aagtattatc agtgttataa cattgaattt tttattcttc ataaatattg
    22381 ccccctttat attaccaact aaatataata tatcttatgt tacttacata ttctttaaga
    22441 aattctgaag attttataaa gttttttgta ttataattaa ttaaaaataa aattctagtt
    22501 ataaaacata ttttccatta aacaaaaaaa tagttaaaat aaattcataa ccacataaac
    22561 ttattttaac tatttgtata ttttaattat aaatattaac ttaaattttt aacaggatac
    22621 actcataaaa taaacataat gaacaacaaa ataatatgtc tcagtttctt tatatacttt
    22681 accttctttc aattttctac catgtagacg tataagataa tattagtaat tcactctatt
    22741 gcttaactcg tgcgatatgg acaaccaaga aagctatttc ctcatttgtt aacttttttc
    22801 catatttctt ttctaaaaaa tctctaactt ttaatgcaat taacatttct tttggatttg
    22861 accttttcat ttgattaaat aataaatcat caccactgct taacatacta tctgaaaaaa
    22921 atctttccac aaaaaatttt atatgtgtta taaatctcat ataatgcata ctctttttat
    22981 ctaaggttct attcaaagaa aaaacaaaaa tattaattat ttctccaatt actttggcat
    23041 acttaatcgt atcatatgaa tttccatctg aagccatagc atttgcaaaa tggaaagcaa
    23101 tgttagctgc ttcttcctct ggtaattgaa tgcccaatct ctcctctacc atataaattg
    23161 caaccattcc aaccttaaac tcatttggat aataattttt tatttcccaa aatactcgat
    23221 ttgtaatttt tattccttta cgcatccttt caattgcaaa gttaaaatgg tctgctaata
    23281 ttaagtataa gtttttatta aaagatgagt tcaataactt ttctgcctct actattattt
    23341 cctgtgttat ctttaaaatg tcgacaggaa tatcatccat taattctaaa aattgttttg
    23401 attttgtatt ttcaacaggg acaaacattt gattatcatt ggaaccacaa atatattctc
    23461 ctgttttttt accatatcca attcctttcc ctagcaaaat aaattcatta tcctttgtgt
    23521 catgaactaa aacaacgctc gagttcaaaa ctttctttat tatgtagttc attttatttg
    23581 ctcaccttct attggtcatt taaaatctat actattactt tcaattacct ttttatacca
    23641 ataaaaacta tctttcttat atcgattata tgtccccttt ccataatcat cagcatccac
    23701 ataaatatat ccataacgtt ttgacatttg tttcgttgat tcactgacca aatcaataca
    23761 accccatgaa gtatatcccc aaagttcaac accatcttca ataatcgcat ctaacataca
    23821 tttaaagtgt tcttttaaat aattaattct atattggtca tgaacttttt tatcttcagt
    23881 taaaatatct ttggctccca atccattttc aactataaat aaaggctttc tgtatctatc
    23941 atataattca atcaaagata tacgtagacc tattgaatca atttgccaac cccattcact
    24001 catttctaaa taaggatttt ttacagctaa taacgtattc ccaggtgtaa tatctaatcc
    24061 agttgtatca gctgcctcac aagaagacat atagtaagag aatgaaataa aatctactgg
    24121 atactttttc ataatttcat catcatgttc ttcttttact atttgaatgt tattattttt
    24181 aaaatacgac agtaaatata ctggatactc accaaaaacc tgcgtatcac tatatgcata
    24241 aatacttctc atttttcgtt gagttgccaa aacatcttct ggtctacatg tgtatggata
    24301 atacgttaat tttgttaaca tacaccctac ttttgaattt ggaataattt catgacaaat
    24361 ttttgttgca agggcactag ctacaaattg atgatgcata gcttgaaaaa taacttcctc
    24421 aaagttttta tccttaaaac ggtctcgaac taaaccacca gtagtgtacg gatgacgaat
    24481 catagaatca acttcattaa atgtaagcca atatttcact ttgtttttat atctttcaca
    24541 gatagtttct acatacctaa caaacatatt gataacttgt cgtgaatacc atccatcata
    24601 gtttaaaacg atatttaatg gtggttcata atgtgacata gtaacaagtg gttcaattcc
    24661 ataacttatc aactcatcaa atacatcatc ataaaactgt aaaccttctt catttggctc
    24721 tttatcatct ccatttggaa aaatacgaga ccaagcaata ctcattcgat atgtcttaaa
    24781 tcccatttct gccattagag caatatcttc tttatagtga tgataaaaat cactaccatg
    24841 acgttttgga taatttactt catcttcagg atgtgctaat ccttcttcta tatcttttgt
    24901 tgtgatttca ttattagatt tataatcttt cacatctgca tcaaagtgtg cctttgctac
    24961 atctgataca gaccaccctt taccacctaa attccaacca ccttcaaatt gattagcagc
    25021 tgtagctcct ccccaaagaa atccttctgg aaactttctc atatttatat tcctcccttt
    25081 acatcaaaca agatacttcc tttttttaca ttgccataag actggtttaa cactttataa
    25141 gcataatctg ctccattatt gtttacaatc ataacagttg aatctaaatt agcatgtgag
    25201 attttgtcta aatcaaactg aattaataaa tctccttctt ttacattatc gcctgtctta
    25261 acaaatgttt taaatccatc tccattcata cttacagtat ttattccaat atgaatcaaa
    25321 atctcagccc cattttttgt tcttaaacca attgcatgtt ttgtttcaaa taacatcaca
    25381 acttctgaat cacaaggtgc gtataaattt ccattggtcg gtataattgc aactccatct
    25441 cccaaagtct tacttgcaaa tagttcatca ttaaccttac ttaaatctat tacttttcct
    25501 tctactggag ttactaagat atttacttct ttttcttctt ctagctcttc ttcaacaaca
    25561 tctccaattg atgactctac tgtatttgta tcttccttcc aaataatcag tgtaataata
    25621 aacgagccta atattgcaat aacaaaacca atacttgcaa aaatcaaatt gtttccattg
    25681 tttgggtcaa taaacatact catactggca agccctggtc caacaattac aaatcctttt
    25741 actgcaaata atcctaaaaa tgtaccagaa attgcacttg agaatacaac acctaacatt
    25801 gctcttttat gttgtaaagt aataccatat aaagctggct ctgtaattcc catcaaggca
    25861 gaaattcctg cagataatgc tgtttgtttt aatgtttcat cttttgttcg caaggctact
    25921 gcaaaacaag caccactttc agaaatattg tgggctaatg aagatgtcat atataaagct
    25981 tcataaccca actttccaat tgtattaatt gaataaggta ttagtgcttt gtgcattcct
    26041 gttgcaacca taaatggaag aaaagcagca agtaatccta caactaagaa tcccattttg
    26101 ttatataaga ataaaataat ggttgtaaaa attgtaccaa cgttatatcc taaaggacct
    26161 aaaatagtta gagtaattgg aacagtaatt gccaaagaca tcataggaac aaagaaagtt
    26221 cgaattggtt ttggtgaata cttgttaaaa attttctcca ttgttgccaa gaaagacaca
    26281 cataagatag ccgggaaaac ctgtgcatta taggcaatgt ttggaattgt aaatccaaat
    26341 agttcgacac cttcacttaa agcagttgtt gttgctggaa gcaataagta tcctacagcg
    26401 gcaatagcta ctaaacgatt acatttcaat acattggcag tagttacagc taccataaga
    26461 ggtaggaaat agaatgttgc atctgaaata gcaactaata atgtatatat agtagaatct
    26521 gattttaaaa tattaaacat tgctaataac atcaacagtg attttaaaat accagctcct
    26581 gcaatagcaa aaatcagtgg ttgaaaaata ttaataataa attctataaa tcttgttcct
    26641 aagtttattt tttcttcagt ttttacagta ctatcatttg tatctaaagg gcaaactttt
    26701 aaaatttcat catacacatc aacaacacta tttccaatga caacttgaaa ttgtgcccca
    26761 ttaactatac tcataacacc ttgtactttt tttaaagcat cctgattgac tttacttcta
    26821 tcaatcaact taaagcgtag tctagttgaa cagtgttcta aagctaaaat attttttgaa
    26881 ccaccaactt gttcaataat gtcaatggca gtttttttat aattcatctt gtaatctcct
    26941 tctccataat tttttatgaa tggccattca agatgcaaaa aaggcagaac ctatataaac
    27001 accttgaaaa atcaaagcaa tatattcgat cctgcctgca ttaccagtaa catgtcttct
    27061 atttatacta ttttgtatta ttatattaac atttgcctaa aagaattgtc aatacttttt
    27121 taaattttct gatactaact aatagcacct ttataattca ttttttatat caattaaagt
    27181 aacagtagcc acccaccaat tagtatcaaa attgaacctg gtattttttc ttttatattt
    27241 tctttgaata taaaatgagc aagtattaaa gttattatca tagatacttg agaaaatggc
    27301 tctgctatac taagttctag attatttaaa gcaattaata atgctaaata agaatatcca
    27361 ttaatagcac cacttaaaat tgaaagcccc tttttattac taaaaatctc acaaattatt
    27421 ttttgtttct ttttaaatgc taaaaagata aataaattta aacctacgaa aaaatacagt
    27481 atagttgaat ataatatagg agatacttgt acaaaaaaag ccttatccaa tactcttcct
    27541 actgactgca aaaatatgta taaaaacatt aatctacatg gtaaattgtt aaaaattaca
    27601 gagacattct ttaaaaaaga gcttactttt tttaatataa acactccacc aatcataatt
    27661 atgattcctg caacttttgc taaacttaaa ccttcaccta aaaatataac tgataaaagc
    27721 agtaaaaaca atgaatttaa actatttatt ggagtaacaa gtgaaacttc cccagttgct
    27781 aaagacgtta catacgctac tgaaccaatt gaatagacta aactacttat ataacatggt
    27841 attaaaaacg accaatcact aactctatcc attatgctaa atggaagtaa acatactccc
    27901 cctataaaga aaaatagaaa tgatgaagct atatttttat aaatatctcc ttcttcatca
    27961 cctaataatc ttacaactac tctttcaaaa gctaatagca ctactctaat taataatgca
    28021 aaataagata atatcatttt tgacctcgct taaaaattaa tccgacttat tgttatatta
    28081 actgtataaa actaccatat aggtaagtct tttggatttt ttaatatttt atgtttaaat
    28141 acaggtacat taagtttttc acctagttta cgacattgct ctttataggt accttttaat
    28201 ttatcatgaa aaactataca atcaattcct ccttcaatac tatttataca cttttctagt
    28261 ttctcaaatc cagattcatc atcatacatt ccacttacaa tccattgatt tggcaataca
    28321 tgtccaattg atatgttata ttctttattt tttataatat ctgagaaaga tttctcaaaa
    28381 tgtacccctc caacacataa caaagtcttc aaaggttcat cacaatcaaa tactctaatt
    28441 aatgattttg ccaatacctg tattgctata ctattattaa aactatcact actacttcct
    28501 atctcaatat ccaacatagg tacagaatat tctgtaatta atttagattc ttcaccatat
    28561 gttgttccag accagtgagt tgcttctgtt aatgtagtaa attcatcaag tagattttca
    28621 ttttttatat cctcaatagc attgattaga tttttaaagt atcttggatt tgaatttcca
    28681 aattctcctg ttggaacatc tccaattgta tgagctgtta ggatatgttc tggagcattt
    28741 tctccctcat gccaatttac aactcctgca aaatcataat ctctaaaatg tctatttaaa
    28801 attggaagat aatatttata attatgactt attacatctt ttgtttttac aaaatgaaat
    28861 aagttattgt ttttatcctt aaactctaat acaaaattat catcaataac aatatcagtt
    28921 tgatttaaat ccattatttc ttcacaacat tttatcacat tactggctac tgggtctttc
    28981 tttaaatcac tgcaaaagaa aaaaactgct tttttattat tcatccataa atcacactcc
    29041 tataacttaa atataatata tcttcatacc taaaatcatc taaatatcac tctaattcca
    29101 ttaaattatt tatatataat atactaccat actcatttta gctatacctt tgcctgagtt
    29161 tctatatata tgtgatacat cagctttaaa tcttatagaa tttccactag atacaatgta
    29221 atcttctcca tttattttaa tggttacttc gccactaaaa acagttataa actcttgtgt
    29281 tcctggaagt tcagcatttg aatctaaatt tccaccttct tctatttcaa tcataaatat
    29341 ctcaaatctt cttttggagt caaatggaaa tattggataa cttatatact ttccattatc
    29401 ttcaataaaa tggtctatat cacttttttg aatcaattct atgtcacttt cctgcctctc
    29461 catcaatgat gtaaatgaga tttttagccc attagttatt ttcttcaaag tagatatagt
    29521 aggatttacc tcacactttt caatttgaga tagcatactc ttacttacac cactaagttg
    29581 tgcaatcttg tctaaactaa gatgtttttc tttccttatc ttttttaaat tttcagcaat
    29641 tatttcattt aaactttgca taaatacccc ctaatacata ctaatataag ataaattatt
    29701 ttgattatta aataaactta gtaatttaat agaaactttt tatccattat aatgtacatt
    29761 atgtttaata tacattactt tttttagaat gtaaatagtt ttctgaaatt ttgtgaaaat
    29821 gaataaataa aaaactagta acctatattt ttacaaggtt actagctttt attataataa
    29881 tctttcattt taactataaa acttagatgc acctataagc tgtctcttag aaacaatctt
    29941 agctaggttt gctaatgaag aaatttttat atctttaaaa gaaactaaaa atacaaactt
    30001 aaaatctgta aattcttgat ttatattgta tatatcaaaa taacatctca aattatcaaa
    30061 taagtaatta tcctgtaagt ctgcttctat ctcatcagta gcatctttta aatacgctct
    30121 tacatcttca aataaaacac tgaaataaga ctcatctatt tcttcaccta actcttccaa
    30181 tatttcttct atatctaaat catccatatc aaaagaattt cctgtcaact ggcaatcaaa
    30241 taccaatata ttttcttgat ttatagtatt tgatatatct tgtacatatt cgaagtctgg
    30301 acgtaattct aaaatgtctt ttatttcact gctctttaca tggatttttc cttttctatt
    30361 ttcaattttt aaatctatca tatgctcccc ctttcaatct acaaatcttt aaataccttg
    30421 ttttataatc ttttcaatat ctatccaatt actaactcta actatatttt gatgtttaac
    30481 atctttatta tagttagtat ccagaagtat tactttaaca ccatcatcag ctagttgcac
    30541 tgagtttaaa ggattatctt ctataaatat gtcacaactc agttctcttg ccttttcaac
    30601 tttataatca cttcctaata agtaaacatc tatatctgaa aatccttgtc tcgatagcca
    30661 atttttagtt acatcagtta aacactcatg tctagccgtt acaaaagata aattatgtcc
    30721 tttagataat gtgctaatta cctctgtagc accctctaca atctttgctt catcatatga
    30781 gtgtatatac ttattattaa actccgcata cacatctctt attcccgaac catacaattc
    30841 ttcccaatta tgtgttatac actctgcttc agttatattt ttattaaaga tatcatttag
    30901 gtatggaaga aaatgataag ggcttgttat tgttccatct atatcaatac atatattcaa
    30961 tttgttcatt tttacctcca tgtaacattt attgatttga ttaatcaaat attatagcac
    31021 agctttaatt ataaatcaaa actctggata tgactatacc tatataatac caaaaagctt
    31081 gcatatttaa gcaagctttt cgtaaatttt acatttttaa ctaatatata agtttttcta
    31141 aggttggttc cactccaaat tgtgatttca gttctttata ttcttttaat gctttgtcat
    31201 tattcgtttt agtttttatc gctcttatca ttaaattttt tggtgtatca agtggagata
    31261 tgtattctac tacagaagta tcatatccat tgccctccaa taacaatgtt cttaaaccat
    31321 cagttattaa atctgcaaat ctagctttaa atacaccatg ttttaatatt ggttccatag
    31381 cttcatatct atattgccct aatagctcct tatgacaaca tggtactact actatagctt
    31441 cagattttgc tctaattcct agacctattg ccatatctgt agccgtatca caagcatgta
    31501 gacttattac aaggtcaaca tccctattag gtgtataatt agtcaaatcc tcttttataa
    31561 atgacatatt tttataaccc aagtttttag ccatattttt tgatgcttct ataactacat
    31621 ctgaataatc tattcctata aaataacagt ttttcttcaa tacttctttt atataaaaat
    31681 ttaagacaaa gcttaagtag gattttccac aagcacaatc caagatagtt atacagtctt
    31741 tatcctttat ttcttttaaa atactatcta tcaattcaac aaaatggtct atctgattgt
    31801 attttcttat tttatcattt tttatcttac catcttttgt aagtactcca atttctttta
    31861 aaagtgcatt tgcttgtcct acttttacat aataatctct gttttttatt tgagatgccg
    31921 taaattcatc tattttaggt acttcttcct tattatctaa atattttaca tttaccttct
    31981 tattgtctcc ttcaattaca acaatagttc ctcgctcaac atatttaaat actaatccat
    32041 cataattttc tgcctcttta gaaatattct taagcaactc attaaacgta tataaatctg
    32101 attttccttt aaaattaaat ttatatttat tatcttcctc tattgcaatt cctttaaact
    32161 cttttcttcc agatttaaaa atcacctcta actcaataaa aaaatcccta ttatcaaggt
    32221 ttctttgagt aatccccata aaaaacatat ttagttttcc tatactctgt ttattcatca
    32281 taatctccct tttaacttat atccttaaat cttattaatt aatattattt gtttctgaat
    32341 tatttatttc ttcttttaaa tcgttcaatc tatttttaaa actttctatc tgcttatctg
    32401 ataaatcaag atattctgtt atcttcccta tatatttagg gcttttagta tttattaatt
    32461 tcaaagcact ttccatagat ttttctctaa gctcatatgc tttctttacg tcatctctag
    32521 cattactcaa tgtttctgta tacttctcct tagaaagttc tggaatctgc atattttcat
    32581 attcttttac aacttcttta cacttgtttc tggcatttgt aacatctttt tttatactag
    32641 ataatttagt tatatttttt gctatatcct tagtgtaagg tatgcattct ctcattggaa
    32701 ctaaagctgc tctttctata ttataaattt ctttcttaaa aattcctata ctttccatat
    32761 ctattttttt tatatcttca ctattttttt ctttacttgt atatttatta ttttcttttg
    32821 tattatcttc ttgtttttct gatttattat tcactgaaac attactatca gaattattct
    32881 tttcttttat atcattactt ccttcttcat tactttcttt attttgtata tttctatctt
    32941 gtttgttgtt taaattttta ttatttgata tttcttcatt ctttttatta tcctggttta
    33001 aatcagtact ttctttttcc ttaaaatttg atacatactt ttcatcatat gtctcatcag
    33061 aaatataatt gtgataatac atagactctt ttattttatt aagtccactc atataaatat
    33121 tacttatcat tattgttgta gctaatacca cataaatact actgtagata caagacctct
    33181 taaaattctt gtaatttctg aatatcacta ctaaaggaat aagatataaa aatataaaaa
    33241 ctaatatcca cctcataagt cgtgtctcct ttctcaaaac cgaaatccct caaatattta
    33301 tttttaatca tgtatcttat agtatttacc aatttatgtt ttttaatcgt gaacttttat
    33361 taaattaaat tctgtatagt cacaagatgc taatgtatat tctactccat ttcgaatccc
    33421 cttcaatccc attttaaaag attctttacc atgcaagtga ccataaatca ccttttcaac
    33481 attatattct tcaaataact ttgtaaataa agattcttcc aatttatcat tcgtaggagg
    33541 ataatgagta atcacaatta tttttgagtg accactttta cgagcagatt ctaatgatag
    33601 tctaagtcta tgttcttctc ttttataaac tttttcatca gtctcatcaa atttaacatc
    33661 attaggacat atccagcccc tacctccaca aattgcataa tctttatatt cataaaaatt
    33721 tgtctgaata aaacgcatgt cttcatatag cttatttaaa cttgtaacgg ttgtccacca
    33781 gtaatcatga tttcccttta taagtatttt ctgacctgga agtttgctta ttatatctaa
    33841 atctttttta gcttcggata aattaattcc ccaagatgta tctcctagta ctaagaccat
    33901 atcttcttcc ttaacaactt ctttccaatt atctataatt ttcttttcat gaccatccca
    33961 attacttcca aagatattca ttggcttatt gactgatgtt gaaaaatgta aatcacctat
    34021 agcatacaaa ctcataatat cattcctttc ttaattacac taaataggct gtctcttttt
    34081 agaaattatt ttccattaag aggcagcccc attaatattt agcaaatttt ctacaagtag
    34141 tttttactga actactttat catctacctt agtatcctta tattgctcta ataatatatc
    34201 tatttcttgt tttaattcca aaatttcagt tatattttta tctgtttcag ttctatcaag
    34261 ttttctttgg tactgcatag ctttatgtgt atcacccaag tcatataact cttgtattct
    34321 atttagagta tctctaatag ctatagactt catttggtac atagcctgag ctttcattat
    34381 gtcctctctt atttcactca tttcttggtc taaaagaaag gcagcatcag atgctcttct
    34441 aagcctttca gcaagagtct caggtatgta atggtcatat ttatatttta atgaatgttc
    34501 tattgtagcc cagaaattca ttgcaagagt tcttatttgt atttcacata taatttcctt
    34561 tgaacccgca atggagttta tagggtattt tattataaca tgatagcttc tataaccact
    34621 atctttgtaa tttgtaatat aatctttttc tcctattata gtcatatcat ttcttacttt
    34681 tatcaaatca actatagcat atatatcctc aacaaactgg cacattattc ttataccagc
    34741 aatatcatca atttcagttt ctatatcttt tgcatttatc ctttttaact tagatattat
    34801 ggaagatatt ttttttgttc tacctgtgac aaactctatg ggagaatatt caccttttgc
    34861 taaatattct tttcttatat ttttaaattt tatttttaat tcctctactg catgttcata
    34921 aggtgctagt atctcattcc atttttcgta ttccatattg ctcacccttt atttgttttt
    34981 tatgaccttc tttattttat cataatttat tttgtttttg tatagtaaag caattctcca
    35041 ttttccaata tataccctat ttcttctaaa tcaactaagt aacttatgac agatactaac
    35101 gaagatttaa aaaaatgata ctctttataa ttattgctta aattattgtt atttataatg
    35161 ttttttaata aaatttctaa agatttcggt tctacaagca actctcttat ttgatataaa
    35221 tattttttta aagcattcaa atgtttttct attaatttat aagaatcttc tttcgatata
    35281 acttgcttgc catgccctaa aactaagtac tcaaaatcta tattttttaa tttttctaat
    35341 gaatttattt gttcttgtat atcatataga aacaagaaat cgtattttga taaaatttca
    35401 tctcctatca ataaatcgcc aacaaaaatc acattatcct tcgtcaaaac agctatacta
    35461 ccaggtgtat gaccctgaaa ttcaattata tcaaacattt cattgtttaa ttcaaatttt
    35521 ccagcttcta taaatttatc tatttttata tcatccaaca ttttattttt taagatatta
    35581 tccataaata cattgctctt tcccccaaca atatactttg aaaacaattc tggattttct
    35641 atatataatt tatcgtattc agatgacatt atacacacat ctttataata ttctttaaat
    35701 tgattacaag ctccatagtg gtcatcatga ccatgagtat ttataatata tctaacctgt
    35761 atattatttt catctaatac tttatttact ctcctaggtc ttgaaccaca taaccctggg
    35821 tctatcataa gtgctgtgtt atcttcaaat acatatattc ctgtattcgt gccacctttt
    35881 ataaaaaagg tatttccttt tacttttgta agattcacct tcttcacctc attttgacaa
    35941 tatttatgat acaatttatt acttactaat ataaaactat acaagaacaa tcctttttat
    36001 tctatctata gttctttttc ttattttgta ttctttagat atccttattt tcacattata
    36061 tgctaaattt ctataaagta atgactctat aaaatattca actatacctc tatccctaaa
    36121 gtctatatct atatttccac ttgaataaat atttgagtct aatatcataa gctcatcaaa
    36181 aaagcttaat ctcttagatt tacttaaata atctttattt ggaataaatc tatcacaata
    36241 atctatcctg taatttacta cttcatcatt tatttcaaat ccatattgct ttttcattaa
    36301 ctctctatag ttattatttt tctcaataac attatctaaa tttttattat aatcctcttt
    36361 tttccaatgt ccaaacatcc tacaatttaa tggtctaact tcatatatta aacatctatt
    36421 attagtatct ttaaatggac atgggttctt tcttgtatac tcctcaaaat aataatctaa
    36481 tattttactt atacagcttt tttttaaatc aactctatct tcaagataac aaaatatatt
    36541 caaaaactca attaaattta tacctactga ctccatacaa caatttccac atccagaaca
    36601 atttcctact ggcaaggact tatatacatc atttagtttg tcaaagagct tatttttaat
    36661 ggaataatct atacaattta aaatatcttt attttttata ctagtcatta ttattactcc
    36721 ttgttataat tattaagtta atacaaacaa ttattataac atatttttta aatttaatcg
    36781 catatggagg tattttatga atagatatac aaaaataatt aatatgatgg gaagttatta
    36841 cacaaaagac tttgaaaaag aaaaaaagaa tgtaataaaa gttagagaag ttaaagaaga
    36901 tacagttaga aaatttttct tacaaggtga ctgtgaagtt cttgtagtat ttgaagacac
    36961 tgggaaagaa atacttattg atgacttttc tcctgaagaa gatatcaaaa aatatttagg
    37021 agcaaaattt ataaataaaa aaagatagtt atcaaaaata attctaaaat taaaatttaa
    37081 taaatgtaca gttataattc tatataatta tagttaaaag ttatctttta ttgctttttt
    37141 agactttaag atagcttttt ttctattttt tgtaaaataa ttccataatt cacattaata
    37201 attcacaaaa tgatataata taacaaatag ataaattttt aaatttctaa atacataatt
    37261 aatattttgc gaggtgattt tatgcaaatt tattttagag ttaaggctgt tggcaaacgc
    37321 aaacctatgc tagaacttac cccttttgat gtatctgaca acatcaattg cctaaaagaa
    37381 gctatctctg aaattgtatc taaaaatgtt cttgaatata atgagaaaat cccagaaaaa
    37441 tcaataataa acttcttaac taatgaagaa attgaatctc aagctgatat tggaaaagtt
    37501 ggatttggct ctatttacaa tgagaataaa caatctgtag aaaaggcaat agaggtagcg
    37561 ttacaggcat ttgaagatgg aatctacaaa gtgcttataa atgaagatgt tattgaaaaa
    37621 ctcgattcct ctataaatct gaaaagtgga gatatattta cttttataag acttaccttg
    37681 cttgctggaa gaatgtttta aaataaataa tttggaggta cataaatgtt agaacgtact
    37741 agagtagaaa aaaatcctaa aataattgaa aattttaaaa ataattttac taaatcttct
    37801 tcaaaacagt actacgactt agcaaagtct ctttgggact gcatagaaaa tagttcatac
    37861 tattatagag aacctgaaga caaattctta aatatgataa agaaatacta caattgccac
    37921 tactacgaaa ttaaaaatat ggacgagctc ctttctggac ctttaaaaaa tgcattagaa
    37981 ttaatattta cttctgaaca agtagaagaa ctttgccaat taattaaaag aaagatggat
    38041 tatacatatt caggaggata ttatcgtaaa gggtatcgct caaataaact tgtggattat
    38101 tttagaggta ttataaggtt tatttcaaac tatgttgatt taatttatta tgatttttca
    38161 gttatagatt atcttactct tccaaataag gtcttgtact atgactctat aatgagtgat
    38221 aaaatagcac tagaaataga caaaggaaat caaaaagtaa taagtgcttt agaagaagta
    38281 atatttggag aaaatcaaac tgctctactt acaagacaaa tgataattgg tatcatgaag
    38341 agtcatagtg ataaatgcta tgaaatgctt tctaaacttc ttttggcagc caaacaacaa
    38401 gaaggactta gacagcaaat tgtagagagt ttagatgagg gtacaatttc tgcatcaata
    38461 tacatgttaa aaactatttt ggacaacaat ttagagcgat ttagttctgt tataagagcc
    38521 ttggatacat ggacaggact tggtttttca gaccaaaaac ctggaataat acgtaaatgt
    38581 ttagaacttt catataaatc attgactgat gaaaagttcc gtatagaatc aattaatagc
    38641 aatgataatc ttgaaattta ttttgcctta tgggctactg caacttacaa catatatgac
    38701 tcttactctc ttattgaaaa cttactttct tgtcaggaaa aatataaaaa acttgtagct
    38761 ctttactttt tatcgcatac agaaagtaca tattttaaac attctatagc atctaaaaac
    38821 attaagggtg atgatttaga gatactagca tgggtaatta caaatttcta tgtagaaggt
    38881 tctgttggct actactatag ttggcaaaac agagaaacta attttgactt gtcaaacact
    38941 cctattgaca aagactttga tgctagaaaa gaacaatttg aaagtttaaa acatacttta
    39001 gaaattttaa attcaaagac aaaatcattt tcaggaagtg tatttccatg gacttggatt
    39061 gaaatttctt ctcatgaaat acttaaatgt atgatgactt taacagcata cgatatgaat
    39121 gctcaattta tagatgtgct tatggaaaat tgtcatctta tgagttcaga tttaagagct
    39181 tcacttatag tcaattttgt aaatgaacca aagacagata gacaacgtga atttttattg
    39241 gaatgtttaa gtgataagag tgtttccaat agagaaacgg tattgagtct acttagaaag
    39301 cttgagctaa cagatgtaga attagataag ataaccaatc tattgtcttt aaagacaagc
    39361 tctattagac aaacagtaat aaaaatttta cttgaacaag atgattcaaa tttggaaaat
    39421 attgcttctt cactgataaa atcttcaaat tctcaaaaat gccttggagg tcttgaaatt
    39481 gtaaacttat taaaagacaa tactgctaga caagaactat ataataagct tgttttactt
    39541 atagaagata ttgataaatc taaaaagaat acatctcaag ttcaaatact aattgataat
    39601 ttgttaggta aagcaaaaaa tgattactgc aaagaaaatg gttttggaat atataaccct
    39661 gaaaacaaag ttcaaattcc agaacaattt gattttaaag atgattctaa tagctcatca
    39721 aagcttaata aaattatctc aaatataagt ttatctactc gtgaggattc tgtttctgta
    39781 gcaacaaaaa aagaagcaaa aaaaattctc gatacggata taaataaaat aataaaagtt
    39841 tatgaaaaat ttgatgagct tattactgaa aatgcagatt atgaatatga agttgaaaga
    39901 tggtcaggta atgtagacaa agtactttta ggttattcta cttataactt gactcctatt
    39961 aaatataaag tttctaatga tactcttgat aattatccat tagcagagct ttggagagaa
    40021 actagtaaaa agcttgactt agattacaaa ttaatacttg atattttatt ttatagtata
    40081 agtacatgtg gatataatga aacagaaaaa agttggtttt catctatata ttcaaatgtc
    40141 cttgactcta aaaaacaaaa taaaatatat acaaaacttg aaaaacttaa atttaatgga
    40201 cttacaagaa aacttttaag agttttacta aatgagtttg accataaaga aatatttaac
    40261 tattgtttag aaatatacta taaacttaga aacttattga ctatagaaca atgtaaaaaa
    40321 caaagagttg aatttactaa aaactattac agacaaaatg aatactgccc tgctttaaat
    40381 gcccctattt taaactattg gcttgataaa gcacattcgt ttatttatga tgatatttct
    40441 tttactaagt ttttctacac tacgttttca aattatcagt tgctagaata taagtttcct
    40501 ttctatacta gcataaatgt gtttgctcgt gcacatgaat taggattaat gactgaagag
    40561 caagttaata gagaaatgat aagtggatac aacgcatcaa atataataag aacattgaca
    40621 aatcctagat gggctggcga cacattagaa aagtaccctt ggcttaaaga taatttaaaa
    40681 actgttacaa accgaattat agaaattgaa tcacgtagag gtgatatgcc aacagaggtg
    40741 tctcatctag ctaataatat acaatacttt gaaggtataa attattttgt aaatattttg
    40801 gtcgctcttg gtaaagaaac gttccagaga ggatattcat atggtagcaa ttattcaaaa
    40861 aaagatgttt taagttctct acttaaaaat tgctatccta ctaaagaaga tgactcaaaa
    40921 aaattaaaaa gtttacttaa aaataccgac attactgagt taagattgat agaatctgct
    40981 atgtatgccc ctcaatgggt aaacataatt gaaaaatatt taaactggaa gggtctgaaa
    41041 agtacaattt ggtacttcca tgcacatata aatgaaggct tctctgcaca aaaagaatca
    41101 gaggttgctc tattctcccc tatttcacca cgtagtttca ttgatggtgc atttgatgta
    41161 gattggtttt tagattcata taaaactatt ggggaagaaa gattcaatat actttacaag
    41221 tcagctaaat atataactag tggtggtaac tctcatagac gtgcacaact ctatgctgat
    41281 gctacacttg gtaagcttga taaagacatg ttgatgaaag aaattgaaac aaatagaaat
    41341 caagataaat tgagaagttt ctctttactt cctatgaaaa aaggagacct aaaagaagca
    41401 actttccgtt atgaatttat tcaaaagttt gctaaagaaa gcaagcaatt tggtgcacaa
    41461 cgtcgtgaaa gtgaatcaaa agcttgtact atagcgctag aaaatctagc tagaagtgct
    41521 ggatttggag atgtaaatcg tatgatgtgg gctcttgaga ctgaaaaact aaatgaagtt
    41581 gctcatctat ttaaaccaaa agatattgat ggtacttcaa tttggataga tgttgatgaa
    41641 aacggaaaag catctactaa agttcaaaaa ggcaacaagt ctttaaagag tataccaaaa
    41701 gctattgcta aacatccata tgtacttgaa cttaaatctg tccaaaaaga tttaaagagt
    41761 cagtattctc gtgcaaaaca gagtttagaa caagctatga aaaatgaaat agtatttaca
    41821 gttaaagaaa ttgccaatat ctataaaaat ccagttatct gccctttgat taaaaatcta
    41881 gtatgggtat gtgatgataa tattggatat gtttataatg ataagtctaa gttctttatt
    41941 tgcaatatag aaggtgaaac ttataagttg acggcaaaaa ataaattaaa acttgcacat
    42001 ccagttcatt tgtttgaatc tggtaagtgg agtgagttcc aacatgattt atttagtaag
    42061 caaattgttc aaccatttaa gcaagtattc cgtgagtatt atagaataaa cagtgatgaa
    42121 ttatctgaaa aaactatatc tcgcagatat gctggtcacc aaattcagcc aaagaaaact
    42181 gtagcacttc ttagaaatca gctttggact gtcgattatg aagagggatt acagaaagta
    42241 ttttataaag aaaatatagt ggcaaagatg tttgcacttg cagattggtt ttcaccagca
    42301 gatatagagc ctcctactat tgaaacagta gaattttttg atagaaaaac ttataaaagt
    42361 ttagaattag cttctatacc tccaattcta ttctcagaag ttatgcgtga tatagacctt
    42421 gttgtaagtg tcgctcatgc tggtggtgtt gaccctgaaa ctagccattc tactgtagag
    42481 atgcgtatag caattgctaa agaactttta ttattattaa aaattaacaa tgtcaatttt
    42541 gaaggctctc atgctcttat agcaggtaat ttaggtgagt attctgtgca tatgggttct
    42601 ggtattgtac ataaaaaagg gatgggtgct ttgaatatac ttcctataca ttctcaaagt
    42661 agaggtaaga tattccttcc attcgctgat gaagacccta aaactgctga gattatgtct
    42721 aagatactat tacttgctga agatagtaag attaaagacc ctagtatctt aagtaattta
    42781 taagtataaa aactatccct aaaatatatt ggactttctt aaaaaaaatt agaaagtcca
    42841 atatatacta tactgtaatt tatatagatt aaatcataat tacaaataat ttttatataa
    42901 acttctctta tacattatct ttatggtact tattatatca cacaaaaagt atttttcttc
    42961 tatcttcact agaatctttt aaccctataa aatctatata aaaaatcttt ttctagagat
    43021 ttgtttaata tggcattttc ttgaaaattt ataaacctta tctctaatga agatttattt
    43081 ataggtataa ccttatgtat aaatcttaga tttactatgt attgtctatg ggtcataaag
    43141 aaattaggag gtaggcgttt ttttaaatca tcaaagttct cataaaactt tattatatct
    43201 tcatctttag tgtgtagatt aattgctctt gaatttttct caaacataac tatatcatca
    43261 aaattaatca tatgtatctg cttccttatt ttatatacaa aaagggtgtc ttctataaaa
    43321 ttattattag caatcttatg ggagttaata tggtctattg ctatgttaat tgaatcaagt
    43381 attttttctt ttttaaatgg tttaactaca aaatctatag gatgcacttt aaagctttca
    43441 agactataat cagcgaaacc cgtcacaaat actatatgta tatccttatc tatagaaaga
    43501 atttcttcag cagaatcaat cccattttta tatggcatat caatgtcaat aatcaataaa
    43561 tctattttct cattttttat aaattcaatt gcctctatac catccttaac ttttttaaca
    43621 taatctacat atccagactc tttagctata tttgctatat catctcttac aatcttatca
    43681 tcatcacaaa tcaaaacttt tatcatagac ttttctcctc ctaactaata atattttggg
    43741 attaagatta caaattcagt taaaaaatca tcactattta caagtatact ataatcatac
    43801 ttatctaata tatttttaac taaatgtagc ccatatcccc tatcttgtcc ttctttagta
    43861 ctaaatccat tccaaaatat actttcaaca ttatgtattt taggaccatt attttttata
    43921 gctataatat actgaaattc atcttcatat gcatgtactc ttatatactt cttttctttt
    43981 tttatagtag acaaagactc tattgcatta tctattatgt ttaatagtac tgaactcata
    44041 tcattaggtt caatctctaa attatccata aaatcttgaa tgtagacatc aaaagatata
    44101 tccttttcaa gacattcctc gtattttaat gaagctatag catctaaata agatactttt
    44161 ccataccttg aattttttga tttaaaacta tttgatatat tcattatata ttctttggca
    44221 tcttcatcta gcccagtatt taatagagaa tacaccactt gcaaatgttt caaatagtca
    44281 tgtttttgac ttcttaattt gataattata ttatccttat gatttatttt actatctagt
    44341 ttttgtagtt tatattcctg ttcattatta ttatttatca atcttataac tttaaagcct
    44401 gtataaaaac ttaaaataat taaaaccaaa aaaagtataa tatttaatac tccttcaagt
    44461 aaaaaactat atcctaacct taattgtata tatttagtgc cctccataaa taaaatcaat
    44521 gcaaaacacg atataaaaaa tgttaatatg cctcttttta atatgtctaa ttctttgtaa
    44581 aatttatact tattcattat aagattgcta aatataaaca aagttagtat tactatagga
    44641 aatacaaaat tgttagccat gatttccctc ccctctacaa tttatatagg gattatatca
    44701 ttttaaaaaa attatgtaaa aagttaaaat ttacatatag attaattaaa cttgtaaaaa
    44761 tacagatgaa tttgtacaat taactactta aaacttgaaa atacttactt tgctatatat
    44821 tttagataaa tatataattg atttagttaa gaaaggaagt ggtaaatatg aaagataatt
    44881 tgaaaatagt actaaggtat ataaaaagtt ataaagctag gtctttagca attgttgtga
    44941 gtataattct tgctacatca ctcgttgttg gtattggtac cctctcaaga agtgctcagc
    45001 aagcagatgt agatagattg aaaagagagc ttggaactga ccatgtatac tttaaaaata
    45061 taaagaaaaa tcaattaaag tccataaaat ctagcaaaga tattaaaaat ctgggtataa
    45121 catcttacta tgcgtctaca gatgttaatg aaaaattacc tataaacata ctatatgcaa
    45181 ataaaaatta tttgactagt cattctaaac ttataaaagg tcgatttcca aaagctagca
    45241 atgaggtggt agtcgagaaa tggattttaa atagtatggg cttaaaacca gagataaatc
    45301 aaaaccttac ttttaaatta tatcaaaaag aaaatccaga aacttttaaa gttgttggaa
    45361 tccttgaaga tagatttata gagaaaaaaa agggacaatg tgaaattttt tctaatctca
    45421 atgaatcaga actgaatgat tttacaactt atattgaatt taatgaaggc agtgatataa
    45481 atacaaacat agacaatata ataaaaaatg ctatgttaga tgagaaaagt ataggaagaa
    45541 actcaatgct tatagaatct actatgaaaa acggtacttt agataattca agtaaatacg
    45601 ttgcaattgc tatgagtcta tttgctggta ttgtaatata tagtatctat gttatatcaa
    45661 tataccaaag agtacaggaa tatggcgtct taagagctat tggttccacc aactttagga
    45721 ttttcaaact tatgctttat gaacttttca tacttgctct aatagcaatg cctataggta
    45781 tatgtatagg tatgggaggt gcacaaatat ttaataggtc tgtaggaaat attcaatttg
    45841 aaggaaatat aaatgttaca ccttttgtta ttccagataa aataattctc ttatcaattg
    45901 catgtacaat actaataata ctaattataa gtttctttac atacttaaaa ataagaagaa
    45961 tttctcctat tgatgctatc agaaaaactt ttggagctga taaaaatgta accaaagtta
    46021 attatttaat atcaaaatta actttaaata tgtcagtaac aaaatctata tctgcgaaaa
    46081 acatctttag aaataaaaag gggttcatta taattgtatt atctatgagt ataggaggta
    46141 taatcgtcat aaaagacaat tataaatatt cttttttaga tgtgcaaaac aaatctactc
    46201 aagaacaaac atatatgaat gcagatttta ttctatcaaa tgtttatctc aatgaaattg
    46261 gtaacaatac ttcttttaaa gatataaaag ggtttaatga taatcagata gataaaataa
    46321 aaaatataga tggaattgac aaagtcaaaa ctgctagtat cttaaacaca agaatagagg
    46381 taaataaaat aaatagatta gattactacg aagctataaa ttcaactcct tattataagc
    46441 taaatcctct gttcataaaa aataagacta ctggcaaata tacactaaag caaaagctaa
    46501 aaggttataa tgatgagatg ataaagtcat tagaaaaata cttagtaagt ggaaatataa
    46561 acttgaaaaa aatgaaaaaa gaaaatttag ctattgtata tgtaccagaa atttctaaaa
    46621 cacagaaata cacaaagact tttactcctg gtgaaggaac accagctgta gatataaaag
    46681 taggtgatac tataaaagtc aaatatccaa agggtgggat ggatacaggg ctttatgaaa
    46741 gtctaaaaga taattatgaa tacttagaat atgaatttaa agttggagct attataagtt
    46801 atccttttgc agataatggt atgtactctg gagatgatgg tgtagatgta ataacgagta
    46861 gcgaatacct aaaaaaatta actggtgtag ataagtataa cttagtttat gcagacctta
    46921 atgaaaatgc aaacaagaaa aaaataaata accttttagg taaaattgga agtgaagttc
    46981 ctggaactac aacagtagat atgatggtag aaaaagaaaa ttctgataag atgacatcta
    47041 gaactatgat ttatagttat ggtatagtag caataatgtt cataatcagt gtacttaaca
    47101 taataaacaa cataagttat aacttaactt caagaactag tgaatttgga atgttaagag
    47161 ctattggtat ctctgagaga ggctttaaaa atatgatact ttatgaagga atattatatg
    47221 gtgtactctc aagtataatt actatcgtgt caggaattat aatacaattt aaaatgtatt
    47281 atatgcaggg ctttgtatca tatggattgg gattttcaat agattacaaa atatatatcc
    47341 tagttatttt agcaaatata attgttggta ttctagctac atatattcca tcaagaaaga
    47401 taaataaaat tagtatagtt gaagctataa acattacaga ataggaggga taattatgcc
    47461 tatattggaa actattaatt taggtaagat ttatgggaaa aaggaaacat ctgtacatgc
    47521 actaaagaat gcaaatttaa aaataaataa aggcgaattt gttgctataa ttggaccaag
    47581 tggaagtggg aaaagtacat ttctacattt agtaggtggt cttgaaagac caagtaatgg
    47641 tactataaag gtagatggta aagatatatg ttgtctttca gataaagaat tagcaagata
    47701 tagaagacaa aaggtaggat ttgtctttca acagtataac ttaattcctg tattaaatgt
    47761 aaaggaaaat atagaattac cactaaagtt agacaataaa aaaatagata aagaatatat
    47821 tgatgacctt ataaatttat tgggtcttaa tgaaaggaaa aatcatcttc ccaaccaatt
    47881 atctggtggt caacagcaaa gagttgctat tgcacgtgct ttatctgcaa aaccaagtat
    47941 aatcctagca gatgaaccaa caggaaattt ggacagtaaa actacagaag aagtcatgga
    48001 tttactaaaa agttctataa aaaaatataa ccaaaccctt ataataataa cacataatga
    48061 aaatattgct agaaaagcag atagaattat atctataata gatggagagc ttaaattaac
    48121 actctaaaac tatttataga aaagaggatt taaatgttat tgattttagg taatttaaat
    48181 ttaaacttgg attttgacta cagaataata agagaagaaa atgatgatgt agatatattt
    48241 atagatatta attatcgtag cttagatata gatactgatg gttctaactt atttaattct
    48301 agaatacaat ttccatttgt aagagcattg attctaaggc taaataagaa caatcaatgt
    48361 atgacaattc atttgttaag agatatagat ttattctctg cttttgccaa ctttgaagtg
    48421 gattatactg actctataat aaatataaaa aatcaaaatg agaaagtaat tttaaataaa
    48481 tctatcaaaa aatagtaagg gggccttaat aggccccaat ttttttcttt tctaaactta
    48541 ttatatcatg ataaataaat tagtcaatag aattttctga atatttttat aattttttca
    48601 taaagttttt tatatattat gctttaaaat tatatgtaat aaaaaaattt tccgactaat
    48661 tttaaagtta attgattaaa tacacatatt cgaaattacc attaaattac tgacttttta
    48721 tcatttccat ttagaattta agttataatc tattatttat agttacttct acgtgtctct
    48781 aataaaactc tatttatatt caaatctaat aatttatata caaacccaat agaacctatg
    48841 ttgcacaata gatattattt accataataa acttttagat atatctcttt taattcactc
    48901 atcaatgggt atctaggatt agcacctgta cattggtcat caaaagcttg ttcaaccata
    48961 gcatccaatc tttctaagaa tttagattct tctactccag cctcttttat agtcttagga
    49021 agacctactt ttgcctttag ttcatctatt gcttttataa gattatctac tttttcttgg
    49081 tctgtacttc ctttaatacc tgcaaaagaa gcaaattcag catatctttg tatgcaatca
    49141 ggatatctgt attgtgagaa tgcacccatt ttatttggag cttctgcaca attgaacttg
    49201 attacttcat ttattaataa tgcatttgca acaccgtgtt gaacatggtg gaatgcacct
    49261 aatttatgtg ctaaagagtg acatattcct aagaaggcat ttgcaaaaga cattcctgcc
    49321 atagtagatg ccattgccat tttttctctt gcttctttat cattctttcc atttttatat
    49381 gcacgaggta aatattcaaa tattatttta cctgcttgta gtgctagacc gtcagctggt
    49441 tcagttctta acatagatac atatgcttct aatgcatgtg ttaaagcatc aacacctgat
    49501 gctgctgtta atcttggtgg catctccatc atcatatcag catcaattat agccatgttt
    49561 ggcattaatt cataatctgc taatgggtac tttacacctg aatcttggtc agttataact
    49621 gcaaatggag ttacttctga accagttcct gctgaagttg ggatagcagc aaaatacgct
    49681 ttttcaccca tcttaggaaa tacatatact ctttttctta tatccataaa tctcatagct
    49741 aagtcttgga aatctacttc tggatgctca tacattaccc acattatctt accagcatcc
    49801 attgcacttc ctccacctac agctattatt aaatctggtt ggaaatcagc catagcttta
    49861 gctccttctc ttgcacaagc taatgttggg tctggagcta catcaaagaa tgtagtatgc
    49921 ttaattccca tctcatctaa taaatcagtt aatttcttag tatatccatt attatatagg
    49981 aaagaatctg ttactataaa tgctttcttt ttatccataa catccttaaa ttctcttgct
    50041 gctacaccta aacatccttt tttgaaataa accttttctg gtgctctgaa ccaaagcata
    50101 ttctctctcc tttcagctac tgtcttgata ttaagcaaat gttttactcc aacgttttca
    50161 gatactgagt ttccacccca agaaccacaa ccaagagtaa gagacggtgc caatttaaag
    50221 ttatataaat cacctatacc accttgtgat gatggagtat taactaatac tctacaagtc
    50281 ttcatagcat ttacaaactt ttctactctc tctggatgat ttatagagtc tgcatataat
    50341 gaagatgtat gaccatagcc tccatctgca actaattttt ctgctttagc aactgcatct
    50401 tcaaaacttt tagacttgta cattgcaagt acaggagaaa gtttttcatg tgcaaaaggt
    50461 tcatttaatt caacagattc tacttcacca attattattc tagctgtttt tggaacttct
    50521 acatccgcca ttttggctat tacatgtgct ggttgtccaa ctattctggc atttaatgaa
    50581 ccatcaatta ttactacttt tcctactttt tcagtttctt ctttatttag gaaatgtgct
    50641 ccacgatatt taaattcttt tttaacttct tcatatattt tttctggtac tattacagct
    50701 tgctcggaag cacatatcat accattatcg aatgattttg atactaagat tgaacttaca
    50761 gccattttta tatctgcact ctcatctatt attgcaggta catttccagg cccaactccg
    50821 acagctggtt tacctgaaga gtatgcagat ttaaccattc caggtccacc agtagctaat
    50881 ataaggtctg cctctgccat gacaacatta gttaattcaa tcgaaggaac atctacccaa
    50941 cctataagtc cttttggtgc tcctgcctta actgctgcat catgtacaac tctagctgct
    51001 tctatagtac agtttttagc tcttggatga ggagagaaaa ttataccatt tctagttttt
    51061 agtgctatta gggatttgaa tattgcagtt gatgtaggat tagttgttgg tataactgct
    51121 gataaaacac ctactggctc agcaattctt gtaaaaccaa atgcttcatc tttttctatg
    51181 acaccacaag ttttagtatc tttataagca ttatagatat attctgaggc aaaatggttt
    51241 tttataacct tatcttcaac aatacccata ccagtctctt ccactgccat ttttgctaga
    51301 ggtattcttt gttgattagc tgcagttgaa gcagctaaga aaatcttatc tacctgttct
    51361 tgcgtaaatg ttgcaaattc tttttgtgcc aatctaattt cttctaatct cattcttaat
    51421 gtttcaacac tgttgacaat ttcaggacta catacttcaa catttgattt ttctactacc
    51481 ttttcttttt tctccatact aaaaacctcc ctaaaataat tatgcatctc taatttttat
    51541 taatcttaaa tgcatcatct atatttttaa cttatactta aaataatttt atagatttca
    51601 tctctatacc ttagatttta tttattttac tctcttaggt caagaagttt ttttctgaat
    51661 attttgtcaa tttatttttt aacaaatata ttattttttt tacttttact aaaatttttt
    51721 atctaaatga gatatatttc atttgaataa tttacttcga ctaaataaaa tactaaaatg
    51781 ataatttata tctttcattt tttttactta ttaaatttta tatgttattt gcatgttatt
    51841 tgtataagta gtaaataaaa tttttgtcgt atttttataa aataacactt atttttgact
    51901 tgtatgcaat ttttcttttt ataacaactg tatagtttta aaaaatatat aaactaaaat
    51961 tattctaatc tctataagtt attttta
//
LOCUS       DAMJVG010000019        51850 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.019, whole genome shotgun sequence.
ACCESSION   DAMJVG010000019 DAMJVG010000000
VERSION     DAMJVG010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 51850)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51850)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51850
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.019"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(381..581)
                     /locus_tag="PC512_001253"
     CDS             complement(381..581)
                     /locus_tag="PC512_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003723180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDF2441018.1"
                     /translation="MNNGIVKWFNNEKGFGFISMESGDDVFAHFSAIQTSGFKSLEEG
                     QKVSFDIVKGARGPQAENITIL"
     gene            complement(806..982)
                     /locus_tag="PC512_001254"
     CDS             complement(806..982)
                     /locus_tag="PC512_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441019.1"
                     /translation="MFRDKMDKCTHMLTAYIGSSYDYCDFIDTQLDDFILEYGEKVVE
                     SCLHQVMVLVSKYN"
     regulatory      complement(1036..1125)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(1305..1505)
                     /locus_tag="PC512_001255"
     CDS             complement(1305..1505)
                     /locus_tag="PC512_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2441020.1"
                     /translation="MPKFTCNLKKYRQLKELTQEQLAEKVGVRRETIMRLEAGKYNPS
                     LKLAIDISKIVDTPIDELFIFD"
     gene            complement(1507..1857)
                     /locus_tag="PC512_001256"
     CDS             complement(1507..1857)
                     /locus_tag="PC512_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3796 domain-containing protein"
                     /protein_id="HDF2441021.1"
                     /translation="MIQKKFFMGFCGFLGFLSLRYFSSGNVADLTYIGFFAFFSNFII
                     SKINGDKADERYVQDEKAAMAFTGQLAIIELFILWCITIVSRNIELMCVLLSITYAIT
                     LNVYAIKLYILEEK"
     gene            2019..2208
                     /locus_tag="PC512_001257"
                     /pseudo
     CDS             2019..2208
                     /locus_tag="PC512_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890498.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(2685..2855)
                     /locus_tag="PC512_001258"
     CDS             complement(2685..2855)
                     /locus_tag="PC512_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441022.1"
                     /translation="MHVYQPKTSEYLLNTYAKSYLSSIVFLFDYITKNESGYAFFIID
                     FPFLSLDIFYKF"
     gene            complement(3244..3738)
                     /locus_tag="PC512_001259"
     CDS             complement(3244..3738)
                     /locus_tag="PC512_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HDF2441023.1"
                     /translation="MKNKKGFTLVELLVVIAIIGILAIVALPALFKNIEKAKIAKLEA
                     DISAIKSASLSYYADESKYTDGGMISWVKKDGKIIINGGFKDDPLADKIENLGMPYNG
                     SYLLMSSPGHEKYLELSILPEGEISKSGLDKLKSDYGSSIDIMNEQNKIDIVIKFLND
                     KSNT"
     gene            4543..4920
                     /locus_tag="PC512_001260"
     CDS             4543..4920
                     /locus_tag="PC512_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2441024.1"
                     /translation="MKEEILIEKLLRVELIVMEYLWKKDTLMPKKKIVKEIKQIYGWH
                     KSTIKILLKRLVDKRYLARYIINFQSYYKIIIDNKEYYTFKKKVLKSSKSIKIMHSLT
                     TIHKNVSKEKLDLLDEYYRNLKE"
     gene            5025..5399
                     /locus_tag="PC512_001261"
                     /pseudo
     CDS             5025..5399
                     /locus_tag="PC512_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430377.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
     gene            5689..6207
                     /locus_tag="PC512_001262"
                     /pseudo
     CDS             5689..6207
                     /locus_tag="PC512_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            6639..6893
                     /locus_tag="PC512_001263"
     CDS             6639..6893
                     /locus_tag="PC512_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441025.1"
                     /translation="MENKDIKLTICIFAFVIGIIVLFCCIGLGQFNMDCIIKQNGGSI
                     ATEQYNIYLEQSISQYRNFGSILVLLGGIGILFDKSVRKY"
     gene            6929..7252
                     /locus_tag="PC512_001264"
     CDS             6929..7252
                     /locus_tag="PC512_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441026.1"
                     /translation="MARDVFSVKMTPLEAQKMVEKNLEADLVSVDIYNLENNKSIIVT
                     IFEKYYARSNSDAGLVVICENTTGKTLVKITSTGSAIGLFQIDWGTGNNLIKRVKKIF
                     IDYII"
     gene            7526..7678
                     /locus_tag="PC512_001265"
     CDS             7526..7678
                     /locus_tag="PC512_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441027.1"
                     /translation="MDNFLFNVLASVTASYIVYLISKLIKKVKSHSTAKSDLKIDINF
                     KYHRKK"
     gene            7872..8795
                     /locus_tag="PC512_001266"
     CDS             7872..8795
                     /locus_tag="PC512_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HDF2441028.1"
                     /translation="MVGAFVLPNYAIILSEMSNLWGNFIMWILVPIITIVLLIIAVSS
                     MQYILVMIAFLLIIYSFIEKKIVMGLVSVLFFTYSIYLCATWEDKSLIADNKVETVKA
                     QRETVEREKEMERRRIQEEVDKERYIEKHGMEISENDLKVKLEALVPQEYKGKKYELK
                     VGKFKRYSMYFDLTVQNEKFSNSEECKKFVKEIANDLKKIKISKAYFKFHSKDDGGIY
                     NSVYIDYFRNIQNNVDNVENLEFNEFELKTEEEEKREQEKIEQEKNSYNNYIQNRVVD
                     PLDRIKKLKELLDSGAITQEEYNKKKKELLE"
     repeat_region   9062..9676
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=9062..9089
                     /rpt_unit_seq="gttttagattaactatatggaatgtaaa"
     gene            9868..10020
                     /locus_tag="PC512_001267"
     CDS             9868..10020
                     /locus_tag="PC512_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441029.1"
                     /translation="MKNRRKDKRGFSVLLDKEKLDKFDEVLEEKNLTKKEWLEEKIDE
                     ELEQKE"
     gene            10140..10954
                     /locus_tag="PC512_001268"
                     /pseudo
     CDS             10140..10954
                     /locus_tag="PC512_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894376.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="toxin Bro"
     gene            11006..11167
                     /locus_tag="PC512_001269"
     CDS             11006..11167
                     /locus_tag="PC512_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441030.1"
                     /translation="MCENLLDNMYIEKRKEEYRIKLLKIRETDIDIYNKLESIVYKLS
                     EKKLEKNNK"
     gene            complement(11496..11960)
                     /locus_tag="PC512_001270"
     CDS             complement(11496..11960)
                     /locus_tag="PC512_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441031.1"
                     /translation="MDFGEVKSELSDKDLKDNEEALNKYKKYYLKVYKYYSEMDSIKS
                     IQDIEIEQSRLKGQLQKNSNPIFALYISIMAVVFSTTINLTFDLSDITNYFIRMIMTL
                     LFIVLLIFLVNKGILPIAIPYRNNIQFYTTALDVLEDMKKKILRERKYKKRR"
     gene            complement(12096..12413)
                     /locus_tag="PC512_001271"
     CDS             complement(12096..12413)
                     /locus_tag="PC512_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441032.1"
                     /translation="MDFGNINLILIGIIVIIGTTIIYLIKPKTAFCSKKYFNKLESIY
                     GNIDKKKTVKLEVLYRYVTGLEYIAIGLFTRRLDITIIAIILVAIITTALYYLIRKKY
                     ITI"
     gene            complement(12696..12992)
                     /locus_tag="PC512_001272"
     CDS             complement(12696..12992)
                     /locus_tag="PC512_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441033.1"
                     /translation="MYFKTYILKREVNNKQLEITRSFDLDNLICTATEILKDNEIDLI
                     ITNEVNNVVWRNEKSTPPARECLVIAIEVYWWYTSIFLLYHINYVIKKSYLNRF"
     gene            complement(13011..13424)
                     /locus_tag="PC512_001273"
     CDS             complement(13011..13424)
                     /locus_tag="PC512_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441034.1"
                     /translation="MKVKSKRSFIVGIIVCMLCCASLVIYCILKDKRFLISSFLLIVI
                     AIFNFCNAFSRKGIVEELHDSADERDLYLTMKTSHILVKIMNYTLFTFTFLFIIAYSA
                     WKNQSLLVIAITLCVIEIFLFVAYLLINIFLEKKE"
     gene            complement(13408..13641)
                     /locus_tag="PC512_001274"
     CDS             complement(13408..13641)
                     /locus_tag="PC512_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2441035.1"
                     /translation="MKTKVREFRTNMGLTQQQLADLVHVSNRTIISIEKEQYSPSLML
                     AYRMAQVFGTTIEELCCLKENKEMEDKKHESKE"
     gene            13860..14234
                     /locus_tag="PC512_001275"
     CDS             13860..14234
                     /locus_tag="PC512_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2441036.1"
                     /translation="MKISKLPEAELKVMRYICEANKVLTSRELVAAMEEKYEWNESTT
                     FTVLKRLERREFLSTEKIGKLTHYNILVKEKKYLRFETKEFLKNIHKNSISSLMSALH
                     GEDDEVDEDKLSELEEYFKNLK"
     gene            14846..15538
                     /locus_tag="PC512_001276"
     CDS             14846..15538
                     /locus_tag="PC512_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2441037.1"
                     /translation="MYNILVVDDDKEIVDSIEIYLKSEGFKIYKAYDGMKALEIITEN
                     DIHLILMDIMMPKLDGIKATVKIREERNIPIILISAKSEDTDKIIGLNIGADDYITKP
                     FNLLELIARVKSNLRRYVTLGNYEDTCKEILKSGALELNTLTKEVKIDGENIKMTPIE
                     YKIIELLLENKGRVFSIDEIYEKVWNEESFNSENTVAVHIRRIREKIEINPKEPRFLK
                     VVWGVGYKIEKF"
     gene            15734..17794
                     /locus_tag="PC512_001277"
     CDS             15734..17794
                     /locus_tag="PC512_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF2441038.1"
                     /translation="MEKYRVLKLVSLIIISISFPLTILLVTIGLAEPKYNIQKTSTKS
                     GIFDISDDFYDSNIFDEGTMASLLPKFKLSVGGKLTSKEKGKFQQEGKSIDLSSSDSE
                     YDKIMINEQASEEYLSYLKNIKVYVINTYTGVFYTNTSYASLYDFKQKTKSYCNVEII
                     NKIGKSSYIKTINGEKFELNNLSLELNEVDEGFEAYVSFPEEPTIEDGIVYTNFQIFK
                     QATEKVRLFFVASLSLAIICLLSIILYIKIKGEVLKRNNVFLLIYSKIPMEFNVILVS
                     ISIAILTIYALAVSYHIDVIALVSLSLLIVSNNIFFINVQLSYLENKMCIFKTSIIVR
                     VILWLIKTVREVSNAIKKVSLARKVIVIVIISLALIMAISTRSIGMGLLFSICIFLGF
                     TIYITKRLSYLSYVIEGTERIKKGELDYKIKITGNDNFTSLAENINNIGEGLDRAIEE
                     QVKSERMKSDLITNVSHDLKTPLTSIINYVDLIKKEESIQPEYINDYINVLESKSKRL
                     KLLIEDLFEASRVSSGNIELQISKIDLVQLLRQSIGELEEKLSKNNLYLKLNVPNDKV
                     YIWADGRRMYRVFENLLSNIAKYSLEETRVYIDVYDYGENVKVTMKNISSYELNFDPS
                     EIMERFKRADESRNTEGSGLGLAIARDLVALQGGKFYIEIDGDLFKANLEFQKYEEEI
                     TNME"
     gene            complement(18000..18323)
                     /locus_tag="PC512_001278"
     CDS             complement(18000..18323)
                     /locus_tag="PC512_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HDF2441039.1"
                     /translation="MNNNYIFFIIIGMYIVTYLPRVLPMLIFSKKEMPDFLKKIMKFI
                     PVAILTSLTAKDVFFNGDSLYLSIANPKIISFMIVLLVAYKFKSIGISIITGVISIYL
                     FGIIL"
     gene            complement(18316..19017)
                     /locus_tag="PC512_001279"
     CDS             complement(18316..19017)
                     /locus_tag="PC512_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HDF2441040.1"
                     /translation="MERTQQLKESFIASIPIFLGYIPIGIVGGILLQKSGLSPFQIAL
                     MVTLVFGGSSQFIAASMISTGASVTSIVLTTFIVNLRHFLMSSNLNMYIKNKSPKFIL
                     PFCHTITDETFAVNYEKFTAGNWSDRNAIYLNFFCLISSVLANFIGAFLGESISIDSS
                     ISGFILTSMFIALIVSQIKNKIYIVVFISSIIISVILYALFKSNLVIIVASILASLIG
                     FFIEESYCKKEESYE"
     gene            complement(19295..20680)
                     /locus_tag="PC512_001280"
     CDS             complement(19295..20680)
                     /locus_tag="PC512_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDF2441041.1"
                     /translation="MPINSFENYPMNWKPKRPSKGQILYKALVEQLEQDINNGFLLPG
                     TKLPPQRELADFLDVNVSTISRAFKICEKKGLISGVTGSGTFVSYDTRSNLFLMSSNN
                     KITFIEMGTMNPDFTLEEMNTLFKHIIKEIDFKTIFQYGQRDGAKWQKEAIAKLIYKA
                     GLETTSDSLLPASGGQNAIVAILAGLFQHGDRIGVDPLTYPGIKTAAKMLGIQLIPIK
                     QEDNEISEEGLLYACKNENIKGLYIIPDYQNPTTHIMSQNGRKMIANIASKYNLIVIE
                     DAIHSLLNETHLNPVASYLPNQTIYITSLSKIIAPSLRLAYISTPKQYREALSSALYN
                     INLSQSYFLTEIAYRMITSGEADKLINARRKSARRRNKIINQYLSGYNLLGNEECIFR
                     WLILPDGIMAEKFEIQALKEGVQVYASERFAVGKEKPISAIRIAVCATESTEELKAGL
                     SVLKRLLEEKK"
     gene            complement(20788..20931)
                     /locus_tag="PC512_001281"
     CDS             complement(20788..20931)
                     /locus_tag="PC512_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441042.1"
                     /translation="MYDCDNQPKTPEEAVLYTRKRNFNIFKKTIPLYDKEGIKIIGRF
                     EIN"
     gene            complement(21126..21548)
                     /locus_tag="PC512_001282"
     CDS             complement(21126..21548)
                     /locus_tag="PC512_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HDF2441043.1"
                     /translation="MNTFKTEVLLKYSAKDIFNIFTKSARLNFPNFNEKKAVGTFVQQ
                     KNNKRFKVEITNFEKNRVYEIKTSNKRESTITRYELVHIDLENTKLIFIESESKRNIF
                     GKINSALVRVLFGKRQPEEFNKFIKKLEMELENNSVNL"
     gene            22026..24929
                     /locus_tag="PC512_001283"
     CDS             22026..24929
                     /locus_tag="PC512_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2441044.1"
                     /translation="MELRDKLVNIINTENKKDPLTDVQIAKFLSTTRENITNLRKELN
                     ISNSRQRRYPYLKSAISAILQKNKNISVSEITRELMTEGFNISRRVVEELLPKESLEM
                     DVVEESEEESNDPFETLIGNKGSLRNAVEQAKSAILYPPKGLPTLIIGESGVGKSLFS
                     RHMYEFAKQKKIVKESSNFVVFNCADYSDNPQLLLSLLFGYKKGAFTGAEYDTPGLVE
                     EADEGVLFLDEIHRLPPKGQEILFSILDRGKFRRLGETNAERKVSIMLIGATTENVET
                     NLLLTFRRRIPMLITLPPLHDRLLKEKIDLIYNIFQQECNRINAKIFVDKNVIEILAL
                     KKFSGNIGQLQNMIQVLCARAFMKFINSKDEDSESIVVVDINEVLKLKDSFKDAAFQE
                     IEYTEIRKYLKNAIFIPFNLEESSVKGSLLSDEYILPEDIYKTIEKKYYDLKSLDIED
                     IDIENILWTFILNRFADLKFNLDSNEEIFSMSDLNSFVSDSLVKLVKELMNDIVEKNM
                     NLEVNKNMFKYLAIHLEEAIKRIKLNQKIINVNLEKIKIDFSKEYEISKSFAIKIEES
                     IGIKIPDDEIGFITLYIKSALKNEVKKDKVGLIIISHGRIATETVNVVKELLGVKFPV
                     AIDMPLDEKPINIYNKAVELSKIIDQGKGILFLVDIGSLTNIGQIVNKRTNISTKTID
                     RVDLLMALEATRKVSMGEEELDEIFFSLLKDRMGYNYELEKHIDKSNAIVTLCLTGEG
                     TAKYISKTLEEKYDNTKCYQMSALDENLFCKIENLKETNNILAIVGTINPKIPGINFI
                     PYNKELFKNLDIYLSKSKQQDDRPVKSYERMLDEDLVIFEPDIYFKKDLLEYVCSILI
                     NKEYVEKDYLDSVLHREEMLPTYSKGAIGVPHGDSSTVNSTRFVFVKLKNPIDWGVGN
                     VNFIFMPVFQANDKEIVKNVLEILKDAEFMNNANKCFDKDAFRRIIFDKFKHL"
     gene            24962..25408
                     /locus_tag="PC512_001284"
     CDS             24962..25408
                     /locus_tag="PC512_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2441045.1"
                     /translation="MNVDLISLGLESNDYESVIEELGSIMCKKEYVKETYINAVLERE
                     RTLPTGLDIGEMCVAIPHTDSKHVNESNVAVGILKNPVKFNSMIDPKDRLDVELVFLL
                     AVKNPDSQVKLLKDLMSVFQNIKLLKNIKNASTKEEVAKLLDFIEI"
     gene            25531..25833
                     /locus_tag="PC512_001285"
     CDS             25531..25833
                     /locus_tag="PC512_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2441046.1"
                     /translation="MKQFNVLSVCGSGTVTSSMVAGKLKEVLGNKGISITTTEARPTE
                     ALNLAQSGRFDFITFTSPLQTGDYGIPTINAFACLTGIGEEAFFEEVLTVIEGIDK"
     gene            26014..27420
                     /locus_tag="PC512_001286"
     CDS             26014..27420
                     /locus_tag="PC512_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HDF2441047.1"
                     /translation="MLEFMKSIIDTFGSAIIVPIIIFIIAKIFKVTTKKSFLSAVYAG
                     VALQGFTLILNSFTPIITPVINRMVESTGVNLPVFDVGWQATSLVAFSTSAGMIYLGL
                     GILLQTILFLIKWTDVFQPSDLWNNYSYMVWGAMVIGVTGNFPLGIACMVLLNLYSLL
                     ISELVAKRWSSYYRYPNCTIIAMHNVEASVFAVFADPIYNKLGLNKIKLNPKELEKKL
                     GFLGEPITLGLFLGMFIGILGNMTRINTMEAWGEIMKVGISTSAVMAIFPKVASMFAQ
                     AFAPITEAARKIMQKAGNREWYIAVNDAVGYGEPATLISGLILIPIMLVIAMVLPGNK
                     VLPVVDLLAIPYMVQGLVAIHNGNIPKVLVSGIIWFGLGLYVCTSTAPLFTDMATNIG
                     VAIPAGAMLITSFNILGKPLMGLVFFAFLSANPIYIGLSVVIYFVLWALFRKNKTSIL
                     DYLEKQALKNVEEEPVAV"
     gene            27764..28822
                     /locus_tag="PC512_001287"
     CDS             27764..28822
                     /locus_tag="PC512_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012101107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HDF2441048.1"
                     /translation="MGDKMRASVLYSVGDVRYEMVDIPEITDTQVLVNVKYVGICGSD
                     LPRSMVSGLSGNTKYPLILGHEFSGEVVKIGEKVKHINVGDRVAVAPLVPCGKCDYCN
                     EGNFGLCDDYNIIGTRVNGAFAEYVRVPEEHILKLPDTLDYETAAGIEPATIAYHGIS
                     KSNIRVGDSVVVLGCGPIGQFVIQWAKVFGASKIIAVDIFDEKLELSKLLGANYILNS
                     KEVNVIKEIKKITNGGADVVIETAGSRFTQEQSLFVAKKRGNIVFVGISHTELPLSAD
                     ATECILRGELTLKGSWNSYTSPYPGRAWTATLDFMGKGDIIFKPMISHKIGLNEVGDF
                     LSKMSKREINFNKILVEI"
     gene            28921..29607
                     /gene="araD"
                     /locus_tag="PC512_001288"
     CDS             28921..29607
                     /gene="araD"
                     /locus_tag="PC512_001288"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HDF2441049.1"
                     /translation="MLENLKEEVLKANLELPKKKLITYTWGNVSGIDREKGLVVIKPS
                     GVEYSNMTVEDMVVVDLEGNIVDGKLRPSSDTPTHLVLYKEFEELGGIVHTHSSWATI
                     WAQIGKSIPSCGTTHADYFYGSIPCTRKMTREEICNEYEKETGNVIIEEFMGRNPIHC
                     PGIIVNDHGPFTWGKDANEAVHNAVVLEEVAKMAYYTELMSPDNIMDKVLMNKHFSRK
                     HGKNAYYGQK"
     gene            29625..30272
                     /locus_tag="PC512_001289"
     CDS             29625..30272
                     /locus_tag="PC512_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HDF2441050.1"
                     /translation="MLDSLKGKIVEIAIKAEHYGLCKEKTGNFSIRDKDTGYILITPS
                     GVGREELKVEHICVLDLDGNVIEVEKGIKPSSEVLMHIEIYKTRENINAISHTHSLYA
                     TAFSVAKKPIIPIVYESVNYGGYVDIAPYERPGTLKLAKSVSKLLIDTDACLLERHGL
                     TTVGNDLDEALLKSRYVEEVAEIYYRSLVLNQFKELEVVDVDEFKSWKYPEEIKF"
     gene            complement(30445..31812)
                     /locus_tag="PC512_001290"
     CDS             complement(30445..31812)
                     /locus_tag="PC512_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HDF2441051.1"
                     /translation="MNLIDILNKVDAFIWGPPLLVLLVGTGILLTVKLGVVQITKLPR
                     ALKLIFSAENKGSGDVSSFAALCTALAATVGTGNIVGVATAIKAGGPGALFWMWIAAF
                     FGMATKYSEGVLAIKYRTKDKNGQVSGGPMYYIVNGMGEKWRPLAIFFAISGILVALL
                     GIGTFTQVNSITDAINNSFGIDPRITGVVLAVFVALVVFGGLKSISNVATKIVPFMAV
                     IYVVICGIILISFWNKIPETFMLIIKSAFTPTAATGGFLGATMSLAIRNGIARGVFSN
                     ESGLGSAPIAAAAAKTEWPAEQGLISMTGTFIDTIIICTLTGFSLVISGVWCSDLNGA
                     VMTQAAFNGAIPTFGPILLTVSLTLFAFTTILGWSYYGERCFEFLFGVKGMNGYRTVF
                     VAMVLLGAFLKLEVVWIIADIVNGLMAIPNLIALLALSPIIVSETKKYFEHINSPENQ
                     IKKNA"
     regulatory      complement(32002..32090)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            32518..34638
                     /locus_tag="PC512_001291"
     CDS             32518..34638
                     /locus_tag="PC512_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HDF2441052.1"
                     /translation="MGKILVLAEKPSVGRDIAKVLGSKNEKNGYIEGPKYVITWALGH
                     LVTLADPESYGERYKSWSLEDLPILPKHLKTVVIKKSGKQFNTVKSQMNRNDIDEIVI
                     ATDAGREGELVARWIIEKSQVKKTIKRLWISSSTDKAIKDGFAKLRSGKEYENLYYSA
                     IARAEADWIIGINATRALTTKYNAQLSCGRVQTPTLAMLLKREEEIRNFKPKEYYGLE
                     LIATKGNSDIKFIWNDKNNNSSTFSKEKIESTLKKVKGVDIKISEVNKSYKKKYSPAL
                     YDLTELQRDANKMFGFSAKETLSIMQKLYEHHKVLTYPRTDSRYLTSDIVGTLKDRIK
                     AVNISDYSKTCNKLLKSNIIANKSFVDNSKVTDHHAIIPTEQKVFMSDFSDKERKIYN
                     LVVKRFLAVLSPPFEYEQTTISATVEGEIFKAKGNKVINLGWKESYKDIEDEDEYESI
                     PNILEKDVLKVKGLKITSGKTNPPPYLNEGTLLTAMEKNGLGTVATRADIIEKLFNSF
                     LMEKKNKDIYITSKGRQLLDLVPVDLKTPELTASWEKKLLDISKGKLSKNTFINDMKD
                     YSKDIVLEVKNSDNKFKHDNLTKNRCPECGKFMLEVNGKKGKMLICEDRECNTRKTIS
                     QVTNSRCPNCHKKLELRGEGEGRIFTCSCGYREKLSSFNKRKQEEKQKASKKDVNQYL
                     KNQNKNQETFNNPFAEALAKLKNK"
     gene            34742..35995
                     /locus_tag="PC512_001292"
     CDS             34742..35995
                     /locus_tag="PC512_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FliS"
                     /protein_id="HDF2441053.1"
                     /translation="MDLSGIFKYYCKECENTWNNSSVELFENIETYSKDSQKKREKEL
                     DKLLNTISVHLERYPSDAVLRKMWVKKGEVFLQKTLEKENIFKLEKMDVEDRKKFLDI
                     TKQFIRDARKFDDDLPIGDIMQAMRNVWISNALQLLFGKEVYYSKANFAYSMLYPYTD
                     NYLDNTNIDKNDKILFNNWLEKRLLGEHIKSKDYHESKVSKMIDYIESVYPREKFTEV
                     YESLLLIFKSQVNSLKQHGKENHLCKEDLLSISIEKGGSSVLVDGYLISGLMTKEEIE
                     FCIGYGFLLQISDDLQDIKEDLKYNHKTIITEMSKEGTLDKVVNKLINFTIELIDSFK
                     INNKNKSVITMIKNDCLMLILFSVVYNAEFFSVGYIKEVEKFIPYTIDYSLEIEEKIK
                     EKFKNIDVLNNENEYKEMIDIICAE"
     gene            complement(36148..37209)
                     /gene="ytvI"
                     /locus_tag="PC512_001293"
     CDS             complement(36148..37209)
                     /gene="ytvI"
                     /locus_tag="PC512_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YtvI"
                     /protein_id="HDF2441054.1"
                     /translation="MDIQKQKNFIIKFTYVVLITSIVYIVLKFLLPLLMPFVISFIIA
                     SILRPIIRLITNNTNLNRTLISIVILLIFYGLCIFLLVSFGVKIFASVSDVFFRLPEI
                     YKSSIQPTLNTLFSKIDASTPNVNLALILGWDNISQSMMSLVASISTNALNAIASIAS
                     KTPAFMLKLIITLIASFFFTFDYQKIVNFILKQFPEKSQFMIINIKNSSINALLKLLK
                     AYAILLSVTFIELLIGLTILKVENAFTISVIIALVDILPVLGTGSILTPWMIISLING
                     NINLAIGLLILYIIITVVRQILEPKVVGHQIGLYPLITLMCMFVGAQLFGIAGLFGFP
                     IAATIIKNLHDNGIITAFK"
     gene            37483..38223
                     /locus_tag="PC512_001294"
     CDS             37483..38223
                     /locus_tag="PC512_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase"
                     /protein_id="HDF2441055.1"
                     /translation="MKNFRDLGGNKTEDGRTVKKGLFYRSAKLSNLSENDIKILKELN
                     IKYIFDYRSDEEARKHPSTIISNIKNIRIPAMRELEESGGSFGSIEDMIDGLFEKDGA
                     FNMLNNSYYNLPINNPSYKKLVELIRDYSNLPILNHCTAGKDRTGVGSAIILMILGVS
                     RENIMKDYLKSNDFADKEIERFIEYKPKFKDIPKENLKYIFGVNEEYMKTAFRRIDEE
                     YISVEAYLYGEFNLNKEEIRKLRNQYLE"
     gene            38235..40013
                     /locus_tag="PC512_001295"
     CDS             38235..40013
                     /locus_tag="PC512_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF2441056.1"
                     /translation="MSLNITARQINIIKILLNSKDTISGIALSQEIGCSSKTIQNEIK
                     DINKQLRNGKILSIRGVGYKLEGSFDEVNLNSNLYDDVDRVEYIIRKILTLSNEEKNT
                     IKLEDLADSMYVSVSTVKNDLKEVKRMLEKYSISVKSKHKQGICVLESEDKILNCIVD
                     LSNKRDNQLSLNDFLNDDIKERKLLIKKLLLDILNENGLVLTDIEFKSVLNNILVMLS
                     RHKYNEKEFIENYIENYRSKRSSILENEQNKEIIINSIKTFCKNLKLATSIDISNDKV
                     FEEFLYKHISSLCKKIKLGINQSPIMAQDIKIKYPFAFELANIAKKTIEKDLKIEINE
                     DEVANIALHIGGAVERASYNNKDKVFKTIIVCTSGIGTSMLIKAKLENIFKEKLEILK
                     IIPSYLVEYIKVIDVDFVISTVPIEVGDVPVINISPILSEKEIRLIEKYIETGNIYLD
                     LDIKSLFDSELFFTDLVFKRKEEVIDFMASKLVQKGYIDEDMKKSYFEREKIATTEIG
                     NMVTIPHGAIGKIFDNKIAIGILKKPISWEISDVRLIIMLALDKDKILDYEVIFSKIY
                     KRVDSIAKVISICENSSFEKFVNLFN"
     gene            40180..41097
                     /gene="pfkB"
                     /locus_tag="PC512_001296"
     CDS             40180..41097
                     /gene="pfkB"
                     /locus_tag="PC512_001296"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HDF2441057.1"
                     /translation="MIYTVTLNPSIDYIVKLDELKTGSTNRVKEEYVYPGGKGINVSR
                     ILKELGNDNTSLGFISGFTGEYIIRTLEEKELKTDFIKIKSGFSRINVKIKALKETEI
                     NGQGPNIDDEDIDTLYKKLDKLNQDDILILAGSIPSTLDEKLYENIMARLEKKNIKVV
                     VDATKNLLLNVLKYKPFLIKPNNDELEELFGVKLNSIEDMVKYARRLKEMGAINVLVS
                     MGKDGALLITEEDEVLISDVPKGKVKNSVGAGDSMVAGFISGYLNTGKYDYALKLGAA
                     SGSATAFSYDLAKREYIDKLVNEISVKKF"
     gene            41134..43053
                     /locus_tag="PC512_001297"
     CDS             41134..43053
                     /locus_tag="PC512_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2441058.1"
                     /translation="MKIIDLLDEKSIKLNLNSKTKSEAIEELVDLVANSGNLNDKENY
                     KKAILAREEMSTTGIGEGVAIPHAKNSSVTKACIAAAVSKEGIDYESFDGSLSNLFFM
                     IAAPDGANNTHLEVLSRLSTILMDEDFRNKLINSSSEKEFKEIIDKKEREKFSEEYQD
                     EKVAEKNIIDTKENDANKYPKVLAVTACPTGIAHTFMAAESLNKMAENKGVSIKVETN
                     GSAGVKNKLTKDEIENATCIIVAADKNVEMARFNGKKVIKTKVADGIHKAEELIDKAV
                     NGDAPIYHGGDGSHNESNEESESGFRKVYKHLMNGVSNMLPFVIGGGILIAIAFLLDD
                     YTINPSNFGSNTPIAAFFKGIGDKAFGFMLPVLAGYIAYSISDRPAFVVGFVGGALAG
                     DGGSGFLGALLAGFIAGYLVEGLKKIFSVLPASLEGIKPVLLYPLLGTLLMGIIMTFL
                     VIPPVTAINNAMVGFLNGLGGTSKIVLGLVLGGMMAVDMGGPVNKAAYVFGVASLESG
                     QFEIMAAVMAGGMVPPLAIALATTFFKNRFTKEERDSGKVNYVMGLSFVTEGAIPFAA
                     GDPLHVIPACVGGSAVAGALSMLFNAALRAPHGGVFVIPVVTHPFAYILAIAVGALVG
                     MMLLALLKKPLNQEV"
     gene            43549..44556
                     /locus_tag="PC512_001298"
     CDS             43549..44556
                     /locus_tag="PC512_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDF2441059.1"
                     /translation="MIFTIIFYKKGRLCLLNLQSKWVNFLKPTYVSDEIKRKKLQVII
                     FFSITYGLSYSLGLLAICFNHLIDSEILAQFMMILPLSSVSIAKFYTEGRNNDKYNFY
                     SSVILFFIIYFFIFIIESLKLISINQFQLMYLMLILISSLCVIVYSYKITSLYIFKNF
                     KIGILLFFYFLFSQIIFGLIISDNQFDYKNFLNYILLPIISLVYIYPFLCEEYGWRSF
                     LQSILFDRFGKKIGIVMVGTCWSLWHLPLQFTLYSPQTPIIGAIANLIYGIGLSIFLG
                     YVYMKTKNIWFCSIMHVLINSLGLIFNDSEIIINYHSIIQRLIFILLFYTPFLFTKEY
                     K"
     gene            44936..46462
                     /locus_tag="PC512_001299"
     CDS             44936..46462
                     /locus_tag="PC512_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDF2441060.1"
                     /translation="MNESYWFLNSSPKEYNKLGENIKTDCLIVGGGITGLTTAYLLAK
                     EGKKVVLVEADKIGYGTSGRNTGKVTCQHDIFYSKIEKKYGLDKAKSYYNANNEALNL
                     VEQIIEENNIKCDFKRETSFVFTEKEDTIKDIKDEYRTCKKIGINCEYHETIENIPLD
                     IKGAISFTNQGQFNPKKYIDGLAKAAVNLGLKIYENTPVVDLEKGKICRVKTREDNII
                     EAENVIISSHSPWYDGLNFYFAKEYAERAYLMVAVLENKLADGMFISIDDPSITFRQY
                     NDGSENLLIFGGGDHKVGQGGTEKEIFDDLEHYGKEVFKVKDFKGKWSAQDNMSFDNV
                     PYIGYINKREDNIYVATGFSKWGITNGTAAGIIIKDLIINNNSDYKDTFNPSRLGSYF
                     SKDFIKENANVAINYVSGKLKIGSGDMPKNNGEGKIVNIDGKRYGVYKDDNGDFYIVD
                     TTCTHLGCELNFNSEEKTWDCPCHGSRFDYKGNILEGPALKPLKLYGHGDNDVNPKLL
                     "
     gene            46490..47047
                     /locus_tag="PC512_001300"
     CDS             46490..47047
                     /locus_tag="PC512_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441061.1"
                     /translation="MNKLLKPITILLYIVYILSAVFFVANKEYGSLGLVAISLVGTFI
                     LSFINKQTERLLSKELYIMLALFIMFSSLLGTCFNFYDINYYDDFLHLWSGIISCIVA
                     FSIIKYFYTQREISKMSKVFLVIFLFMFSMGVASLWEIGEFLMDTFVGTTTQAGGLED
                     TMIDMVDALIGTIITIPFIVKKSNI"
     gene            47569..48612
                     /locus_tag="PC512_001301"
     CDS             47569..48612
                     /locus_tag="PC512_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441062.1"
                     /translation="MLKKWFGIVKKRQKSESAKEEGEVILKNEKILSEEKLIDEEGVV
                     VNIDNEILTKVEVVNDDNEIEEKIIEEDWLISENTIKLDDKEAIINDKNIELCKKEVQ
                     VESEKIGLNKFEGLDQNENYNLEKNVIEEKKVSECLTEEDLEYIKEIKIKRGKSIKAI
                     NLYTKEEWVFDTHIQCSKKLKVPLGYIRENLKYGYMDYFGDAINYLSEVLNIDEYCKS
                     EWSYLDNSKSPSEIFNILNNKIFSIRLSNEKRNEILTNDKIEALKMNYRFECIDEEYD
                     EYFKKYKSIIKRGGKKKVELVNKKGDILEIFKSLEECAIYLQKEKNEVIQMLKYGDTK
                     VGRNFIRYSLRSI"
     gene            48723..49865
                     /locus_tag="PC512_001302"
     CDS             48723..49865
                     /locus_tag="PC512_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDF2441063.1"
                     /translation="MSEEKNPKENTLDESKNSDNVNSKKDDVSDEKNTDNKVKKREIK
                     LNNKTLKAIVAIVAVGAICLGGGYVFGKEAGRKLPATSKHYNSSEVVATIGDKKITGE
                     MLRKRMEPLFYLNAKTTMTDDEIRSYESNMIETMITSDILSSEAAKEKISITNDQLDA
                     QYNNLMSSIESAMGMTKEEFLKQFDLTEKYIKDDMKKELVASKYLNEKSKVTDKEAEN
                     YYNKNKSNYLQVRASHILIKTVDDKGKQVSSSKKAELKKEAEEILKKAQAGEDFATLA
                     KKYSEDSSAESGGDLGFFGKGQMVESFEKAAFALKKGEVSNKLVESDYGYHIIKKTDE
                     KYQPFEEVKSDLVSSLTSEKQNLLIQNLKEKYNVKITDKYQMKAKE"
     gene            50319..51710
                     /locus_tag="PC512_001303"
     CDS             50319..51710
                     /locus_tag="PC512_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HDF2441064.1"
                     /translation="MSSTESVSKKSGHPKSFWLICMTILWERFSYYGLTALLVLFFTA
                     SVAQGGLGLSTQEATSMFGLFTGLIYLTPLVGGWLADKVLGQQKCISIGALLIAIGDF
                     VLFASSTSIAMVWVGLSIIILGNGFFKSSCSNIVGDIYPKTDVSRKDAAYSLFYMAVN
                     VGAFIAPIICGLLSDNVFAVRGASGDIVSYGYKMAFLICGIGMMLGMIIFTLLAPKLL
                     NEVGKYPVTKGNKGEKIEYGPLTKLEKNRIIAMVILFLFVVLFWTAYYQTQSSFMIYV
                     RDNVNRTLFGFEMPVAWLTSLNAILCVALCPVLATLWVKLSHTKRGDFSIPVKMGLGM
                     IIMGVGFIVMVFATLANGPDGMVKASILFIVLTYIFTTVGELFLSPIGLAMFNKLAPA
                     KYATLSMGAWYLTSFFASLLSGKIAGFTATLGFLQIFGGIATVLIIFGLILLGIRNVL
                     TRLMAMDLLTKEK"
BASE COUNT        20770 a         5480 c         8267 g        17333 t
ORIGIN      
        1 ttttatattt attatatttc agtgaaaaaa tagaacattg aaacatatag atatgtttta
       61 attgcttttt attaacaaat tactaaaagt attatatcag aattgaatac aaaagaaaga
      121 gtatgtattt atgagatagt tgaaaatttt gatgtgccac aactaaaatt attatattac
      181 tatatattct aattaaaaga gtacttgtag gtttaagtac atactttata aatatatttt
      241 tgtcagattt attttataaa aagtatttag actaagtatt atttttaagt atttttttgt
      301 tgaagttatt ttttcctttt ttacaaaatg cgtaaataaa aaaaagactc ttaaaagagt
      361 ctttccgaaa aatctatata ttataatata gttatatttt ctgcttgagg acctctagcg
      421 cctttaacta tatcaaagct tactttttga ccttcttcta atgatttaaa tcctgaagtt
      481 tgtatagctg agaaatgagc aaatacgtca tctccacttt ccattgatat aaatccaaat
      541 cctttttcat tattaaacca ttttactatt ccattattca ttaaaaatac tcctattaac
      601 ctatatcaag atatacttga tttacttgtg tattaccaca aatactattg tatcatagat
      661 taacataaat gtctatttaa ttataatttt tagttaacat ttttatttat tcttaatatg
      721 aaaataaatt taaacatttt atattaccaa tatattaatg taaatgtaga taaaactaaa
      781 aagggttttc tagaaaaaaa tctgtctaat tatacttact taccaatacc atcacttgat
      841 gcaagcaaga ttccacaact ttttctccgt actctaatat aaaatcatct aactgtgtat
      901 ctataaaatc acaataatca tatgaactac caatataagc agttaacata tgtgtacatt
      961 tatccatttt atctctaaac ataatgtatt tatcccccta aaaaactttc atgaaaaaca
     1021 aaaagaaaat atctttttgg caactggctg acataactta ttttataagc gttagtccct
     1081 atagctttgc gtcactaaat ttctctagtt ttgccgattt agttttattc tacagattaa
     1141 taatacaata gaattagtta ttattcaaca tatctagctg aaaaattaat aaatttatat
     1201 atgaacgtta aattatctga aaaaataaaa agcccctctg tcaggagtga cttaaaaatt
     1261 gaatttaagt ttgtatttaa aacacatttt taataatgca aaaactaatc aaaaataaac
     1321 aattcatcaa taggtgtatc tactattttt gatatatcta ttgctaattt caaagaagga
     1381 ttatactttc ctgcttctaa acgcataatg gtttctcttc taactcctac tttttctgct
     1441 aattgttctt gagttaattc ttttaattgt ctatattttt ttaggttaca agtgaattta
     1501 ggcatattat ttttcctcta aaatataaag ttttatagca taaacattta aagtgattgc
     1561 atatgtaatt gatagtaaaa cacacattaa ttctatattc ctagacacta tagtaataca
     1621 ccataaaatg aataattcta taatagcaag ctgtcctgta aatgccatag ctgctttttc
     1681 atcttgtaca tacctttcat ctgctttatc accatttatt tttgatataa taaagtttga
     1741 gaaaaaagca aaaaatccaa tatatgtaag gtcagcaaca ttgccagatg aaaaatatct
     1801 aagacttaaa aatccaagga aaccacaaaa acccataaaa aattttttct gaatcatttt
     1861 ttatcctcct tagtaatttt aaaagagata tatttatatc tttatgatac aaatatatct
     1921 cttttatatt cttttgtcaa tagaaaatca gtattataca atatttgtac tgcaccataa
     1981 ttgttagagc aaaaatctac tgcttgagat gtttatgtat gactaaatat gattttaatt
     2041 tcaaattaaa agtagctaaa ttttatttga atagagaagg aagagatatt ttaatagtaa
     2101 aacaatatgg agtttataac cattctcaag ttgaaagatg ggttaatata ttaggagagt
     2161 gtgcactaaa aataaaaaaa attttctata ctatatggtt caagttagat gttataaact
     2221 atatgatgat aactaaatat agtgtacaat aaatcgctaa gtattttgga ataaacaata
     2281 gcacagttat agcaacatga aaataaaaat ttttacatag tggtgttgat gccttttcta
     2341 aaatgaaagg aagaccataa tgaataaaaa caaaaacact aaagaaaaaa taaattaaca
     2401 agagaacaag aattagaata tgaaaataaa tttttaaaag atgagcttga gtttttaaaa
     2461 aagatgtgtg cctcagggaa gccacattaa aaaacagtgg tatcattatt aatcaaaaga
     2521 aagttagatg tattatcaaa aaattagaac ttaaatgcat agcatttttt cataaatcac
     2581 ataaatataa ctcctataaa tgtataattg gaaaagtaaa aaataataaa acaaatagaa
     2641 gatttaaaat atcaatagca tatcagaaaa taacaaatga tatgctagaa tttataaaat
     2701 atatctaatg ataaaaatgg aaaatcaatt ataaaaaagg catatcccga ttcatttttt
     2761 gttatatagt caaataagaa tactatagat gaaagatacg attttgcata tgtattaagt
     2821 aagtattctg atgtttttgg ttgatacaca tgcaataaag aagttgtgtt tgcagataaa
     2881 ttagcaaaac tatagtataa gttgcaacaa taaagaaaat gaaaattatc atactaaagc
     2941 ataaggcatg ttacaatttt attagatagg acattaacat acattaaagt actttttatt
     3001 ataaagagta cttatttttt tgaaattcat taatgtataa actatcaaga atattactca
     3061 acataattta aaaacaactt gaataggtat ttttaaatta tgtgatataa taaaaaatag
     3121 aagtgtatgc caatacactt ctgtaattat aactaagcat tctattcttg aggagtgctt
     3181 ttttcatttc tccaaacaag attgtttatt tcatcagcaa ttattaaata aaatttattg
     3241 tatttaagta ttcgatttat catttaaaaa ttttattaca atatctattt tgttttgctc
     3301 gttcattatg tctattgaac ttccataatc actttttaat ttatctagac cacttttgct
     3361 tatttctcct tctggaagta tacttaattc tagatatttt tcatgaccag gagatgacat
     3421 taatagatat gaaccattat aaggcatacc taaattttct attttatctg ctaatgggtc
     3481 atctttaaag ccaccattta ttattatttt tccatctttc tttacccatg atatcattcc
     3541 tccatcagta tattttgatt catctgcata gtagctaaga gacgcacttt ttattgcact
     3601 tatatcagct tcaagtttag ctatctttgc tttttctata tttttaaata atgctggaag
     3661 tgctactatt gccaatattc ctattatagc aattactact aataattcca ctagagtaaa
     3721 tcctttttta tttttcattt atttcccctc catataaaat taataatata taaattttta
     3781 ttttgttgat ttctactttc tatattttac catatataga caaaaaaatc actttctatg
     3841 acaaatatac tattatttta caatttatgg aaatgattta aaatgacatt tcttgttaga
     3901 aaagatataa gaaatggatt aaaataaaga aaactacagt catatcaatg tcaataatat
     3961 tatttaaaag cagatgaaaa taaaaagagg actcagaaaa taatgtctat ttaattatac
     4021 ttacttacca ataccataac ttgatataaa caagattata ctacattttt tttatgctct
     4081 agtataaaat catctaactg tgtatctata aaatcaaaat aattatatga actatcagta
     4141 taataagtca aaatatgtat acatgaatac atattttaaa agatatatat tattacatac
     4201 ctaaaaaact ttcataaaaa caaaaataaa atatgctttt agtaacttgt taacataact
     4261 tataatttat tttataggca ttagcctata tagctttgtg ctactaaatt tctttgattc
     4321 tagcgattta gtgctattct acaactaaaa taatacaata gagctattta ttgtttggta
     4381 gcattgtttg caaattaaac aaatttatat atatgaatat tattttacgt ttaaaaaaac
     4441 agactaaata tgtagaatat ttggtaaaac ttacctctag tttttgtctt aaaaagctcc
     4501 tattattaat ttaagttaga agaattaagg aagtgacata aattgaaaga agaaatatta
     4561 atagaaaaat tattaagagt agaattaata gtaatggagt atttatggaa aaaagacact
     4621 ctaatgccta aaaaaaaaat tgtaaaagaa ataaaacaga tttatggatg gcataaaagt
     4681 acaataaaaa tactactaaa aaggctagtt gataaaaggt atttggctag atatattata
     4741 aattttcaat cttattataa aataataata gataataaag aatattatac ttttaagaaa
     4801 aaggtactaa aatctagtaa aagcataaaa ataatgcatt cacttaccac tatacataaa
     4861 aatgtaagta aagagaagtt agacctatta gatgagtatt atagaaactt aaaagaatga
     4921 tatagtaaaa atcgaatgta attatttacc ttaattcctt tgtttgtaaa actttattga
     4981 tatagaattt gacatataca taaattggta aagggatgta tactatgaaa attagtaaat
     5041 taccagaagc ggaattaaaa gttatgagat atatttggga atcagaaaag gtattaatac
     5101 caagagaaat caccaagtct atggaacaaa aatatgaatg gaaagataca actatattta
     5161 cagtattaaa aagattacta aagaagagag tttttagaag cggagaaaat agataagtgt
     5221 acacactata atgtattagt aaaaaaaaat aatatcagag attttaaaca aaagaatttt
     5281 taaagaatac acataaaaat tcaatattaa gtttaatgtc agcactatgt agtaaggatg
     5341 atgaagtaga tggtgatatt ttaaatttat tagaagaata ttttaagaat ttgaaataag
     5401 aaaatgacaa attgatacat aataaataaa atgaaggtat gaaattataa ctttttctac
     5461 cttcattttg tttattattc tgaacatgtt aagaaaatga aataagtttg tattttattt
     5521 atataaattt taatagaata tgtatagtat atagtagata gaatgtataa aaataaaaac
     5581 tgttcaataa gaattaatat acattaattc agctgaatcc aatcaaaata cttaaataaa
     5641 agtaatctga aaataacata attcaaatca atttattcaa ataaacctca atttatctca
     5701 aatcttaaga agtcattaaa caaacttgct aaattacaaa gagaattatc aagaaaaaca
     5761 atcggtagtt taaatagaaa taaagcaaga ttaaaagttg caagacttca agaacatata
     5821 gctaatcaaa gaaatgattt tctacaaaaa ctatctacta aattaataaa agagaacgat
     5881 attatttgca tagaagattt acaagtaaag aatatgatta ggaatcgtaa actatctcgc
     5941 tcaatttctg atgtgtcatg gtcagagttt attcgtcaat tagaatacaa ggctaattgg
     6001 catggtagac aaattgtaaa ggtgggtaaa ttctttgcaa gttcacaaat atgcaataaa
     6061 tgtgggtata aaaacgagga agtgaaggac ttaaatataa gagaatggat ttatcctagt
     6121 tgtaatgaaa ctcacgatag agatataaat gcaagtataa atatattaaa agaaggatta
     6181 agactaataa caattcaaaa taaataacgt atgtaagaac cgtaggaact acggggatag
     6241 cctgtggaga attagtaaga catatgttag tatgcaaaat tctgtgaagc aggaaacctg
     6301 tgactttagt catgggaggt tcaggctagt attactcatt attgtattca aaagctaaag
     6361 tggaaaccta gtgaatatat gaatttagaa gttaatgaga gagcattagc agccgactca
     6421 atacttatta aaattgaaga tgaagaagaa acaatgaaag aagctgaaag agagaaaaag
     6481 agaggtagaa gaaggtagaa tttaaagtta aaatagttac attgctaata tatgaaaatg
     6541 ttacaaattt ggaaatagat ggatatatat gttgtatagt ataatgtaga taatatatca
     6601 ccaagtaaaa aacaacaaat aaatctaaat tatgaggggt ggaaaataaa gatattaaac
     6661 ttacaatatg tatatttgct tttgtaattg gaataatagt gttattttgc tgtataggtc
     6721 taggtcaatt taatatggat tgtattataa aacaaaatgg tgggtcaata gctaccgaac
     6781 aatacaacat atatttagaa caatctattt cacaatatag aaattttggt tctatactgg
     6841 ttttactagg aggaatagga atactgtttg ataaaagtgt cagaaaatac taaaaaagta
     6901 tatttttatt taggatgtga tgaatgatat ggcaagagat gtatttagtg taaagatgac
     6961 accactagaa gcacagaaaa tggtagaaaa aaatttggaa gcagatttag tttctgttga
     7021 tatttataac ctagaaaata ataagtctat aatagttaca atctttgaaa aatattatgc
     7081 aagaagcaat agtgatgcag gtttggtagt gatttgtgaa aatactacag gaaaaacact
     7141 tgttaaaatt acctcaactg gtagtgcaat tggactattt cagattgatt ggggaacagg
     7201 taataatttg attaaaagag taaaaaaaat atttattgat tatattattt aattatttta
     7261 tgtagatatt cttaggttgg tatggaattt gtactaacct attaagtaat caataaaact
     7321 aaataaacat agaaagcact tacaaatatg taggtgcttt ttattgaaaa aatagaaaat
     7381 aaaataaaaa gtaagatata ggaaaaatat gtaagaatta tatgttataa taattgtagc
     7441 aagaagatgt aatctacaat ttatagagtg gagttcatgt attaaaaaat tatcctccca
     7501 acgataagaa gggaggtgaa tatacatgga taatttttta tttaatgtgt tagctagtgt
     7561 aacagctagt tacatagttt atttgattag caagttaatc aaaaaagtaa aaagccactc
     7621 taccgcaaag agtgacttaa agattgatat aaattttaaa tatcatcgta aaaaataact
     7681 ttcagttata gaacttcact ctaccgcaaa tagattgtag ttcttcttgt ttttattata
     7741 ccacaaatta gaaaaaatat tgcatataat attttttata gtcaataaaa atatgaaatt
     7801 ttttatacac aatgatgatg aatctaacta gatgaataaa tttaattgta aataagaaag
     7861 tacttactta aatggtaggt gcttttgttt tgccaaatta tgctataata ttgagtgaga
     7921 tgagtaattt gtgggggaat tttataatgt ggatattagt accaataata acaatagtat
     7981 tacttataat agctgtttct tctatgcaat atattttagt tatgatagct tttttgttga
     8041 ttatatattc ttttatagaa aagaaaatag ttatgggtct tgtgtcagtt ctttttttca
     8101 cttattcaat ttatctttgt gcaacttggg aagataaatc cttgatagca gataataaag
     8161 ttgagactgt taaggcacaa agagaaactg tagaaagaga aaaagaaatg gaaagaagaa
     8221 gaatacaaga agaagtagac aaagaaagat atattgaaaa acatggaatg gaaatatcag
     8281 aaaatgattt aaaagttaag ctagaggctt tagtacctca agaatataag gggaagaaat
     8341 atgaattaaa agtaggaaaa tttaaaagat atagtatgta ttttgattta actgtacaaa
     8401 atgaaaaatt tagtaattct gaagaatgta aaaaatttgt aaaagaaatt gctaatgatc
     8461 ttaaaaaaat taaaataagc aaggcgtact ttaagtttca ttcaaaagat gacggcggta
     8521 tatataattc tgtttatatt gattatttta gaaacataca aaataatgta gataatgttg
     8581 aaaatttaga attcaatgag tttgaactta aaaccgaaga agaagagaag cgagaacaag
     8641 agaaaataga acaagaaaaa aacagttata ataactacat tcaaaacaga gtggttgacc
     8701 cactagatag aataaagaaa ctaaaagagt tgctagattc aggagcaatt acacaggaag
     8761 aatataataa aaagaaaaaa gaattattag aatagataat atagtaagca cttacaagta
     8821 tgtaggtgct tttaaattta caaagtattc cattttaatt ttatagttta gattttatga
     8881 tataataaaa atatagaagt tttgcagtgt gcgatatttg ttacaaagta gggcttaata
     8941 cttgaaatct aagatgttga gggtgcgtga taagtgttat caattgcact attgcccgct
     9001 cactgcaatt ttaagagtat tgtatatatg taggtattgg aaatgctaag tttattttgg
     9061 ggttttagat taactatatg gaatgtaaaa ctgactcggg agcatataat aagtaatatc
     9121 aagaatagtt ttagattaac tatatggaat gtaaaattcg taaaataaca attgtcagga
     9181 atatgagaag tttgttttag attaactata tggaatgtaa aattggactc aaaatataag
     9241 ttaaaaaaat ttttaagttt tagattaact atatggaatg taaaaatttt tgacgctatg
     9301 aagaaattta ctacaaaatt tgttttagat taactatatg gaatgtaaaa acttttttca
     9361 tcctcccaaa cctcttgttc gctgtcgttt tagattaact atatggaatg taaaaaagaa
     9421 aataagttta aaaaaaggtt tcattattat atcgttttag attaactata tggaatgtaa
     9481 aaccaattat gtacagttta gttactgtgt taagtcttgt tttagattaa ctatatggaa
     9541 tgtaaatcgg ctacaacggt ataaattaaa tttagcaggg tacattttag attaactata
     9601 tggaatgtaa attgctgtga tttcaataat aaaacaatta ataattgtgt tttagattaa
     9661 ctatgtggat tcaaaattaa ataaacaaag aaagcactta caaatatgta ggtgctttta
     9721 ttctgctcaa aattggtcgg ttgggtaaaa taattagaaa aagttagtaa aaacctattg
     9781 actgtaactc gttacaatat tgttattaat gtaacgagtt acagaaaaga ggtgaataaa
     9841 atagcaacta aaagtagggc agagtatatg aaaaatcgtc gaaaagataa aagaggtttt
     9901 agtgtacttt tagacaaaga aaagttagat aaatttgatg aagtgttaga ggaaaagaat
     9961 ctaaccaaga aagaatggct agaagaaaaa atcgacgagg aactggaaca aaaggaataa
    10021 aaaataaggg tcactcccac cgaccaaagt ttgagtaacc cctatgacgt atactatcgt
    10081 atatcaatta tagtatatgt cattccttaa aaaaatcaat tattaaggag tgtaatatta
    10141 tgaaaaatga attaatgatg tttgaaggaa aagagattga agtatttgaa tttgaaggaa
    10201 gaattttatt caactcaaaa gatgtagtaa actgtttaga cataaaaaat gttaatgaga
    10261 atataagact tatgaatgaa aagcaagttg taaagttaag aaattcggat atcagtaata
    10321 ctgacatccg aaaacttaat aatgctggag aaaattttct tactgaaagt ggagtgtata
    10381 aattaatctt taaatcaaga aaagaagaag ctgagagatt ccaaggctgg ataagtgatg
    10441 aagttttacc aagcataaga caaactggtg catacataaa taataatgca ataccgaaaa
    10501 gttgagagaa aaagcaagtg agattgaaaa attacagttg gtttataaca gtacatctat
    10561 gttaaaagaa ttgctagatg atgcaggctt tgacaataaa tcaaaactat taacagctaa
    10621 aacattatat aagaaagcag gaattgattt accaatagag ataaacgaag aagaacatta
    10681 ttttgataca aaacaaatag catctaaact gaaaatatat tctaagagta ataaaccagc
    10741 tcagatggca gtttgtgaga ttattaaaaa gattgattta gaagatggtg aagttaaagg
    10801 tgtttgggaa attaatggtt cttggactgg tactgtaaat aaatatacaa agagtgtaat
    10861 agataaggtg agaacttgga tagaggaaaa taatagacct accaagattg caggtgagaa
    10921 gaagaattat tatgtatttt acaaaattga gtaaatttat cagttgtatt aaataattta
    10981 gtttagtttt ggggggatta atacaatgtg tgagaattta cttgataata tgtatattga
    11041 aaagagaaaa gaagaatata gaattaaact tttgaaaata agagaaacag atatagatat
    11101 atataataag ttagaaagta tagtatataa actttctgag aaaaaattag agaaaaataa
    11161 taaatagaca tataaagcac ttggatattc tactgtttca agtgctttgt ttggtataaa
    11221 atggtataat ggagatagag aattatatta acccaaaaat ggagaaaata gagaagatga
    11281 tttagttgac gctttatcag taggagtact tgcaggtaag acagaatctc tagtactatt
    11341 agttggaaat ggaataagtg atactcaaaa aagtttaata aataaaagag aatttagaaa
    11401 tataactcaa attggtggaa atggaaatga gaaagcattt agtgaagtag aaaacttagt
    11461 taaatagatt agaaggtagc aactagagtt ggttgttacc ttcttttttt atactttctc
    11521 tctctaagta ttttcttttt catatcttct aatacatcta atgcagtagt ataaaattgt
    11581 atattatttc tataaggtat agctattgga agaatgccct tgttaactaa aaaaataaga
    11641 agtacaataa ataaaagtgt cataatcatt ctaataaaat aattagtgat atctgataaa
    11701 tcaaatgtta agttaattgt tgtagaaaat acaacagcca taatagatat atacaaagca
    11761 aaaatggggt tactattttt ttgtaactgt cctttaagcc tagattgctc tatttctata
    11821 tcttgaatac tttttatgga atccatttca ctataatact tataaacttt taaataatat
    11881 tttttatact tgtttaaagc ttcttcatta tctttaaggt ctttgtcact taactctgat
    11941 ttaacttccc caaaatccat aaaatccctc ctacaatgtt atataatata ctttaattta
    12001 tagcatattt aagaacttat atcagcaatt tgtcgaacga ttttagctaa aaatagagta
    12061 taatgatagg cttattattt ataagatatt attttttata tagttatata tttctttcta
    12121 attagataat ataatgctgt tgttataatg gctactaata ttattgctat tattgtaata
    12181 tctaatcttc ttgtaaataa gcctattgct atatactcaa gacctgttac atagcgataa
    12241 agtacttcta gtttaacagt ttttttctta tctatatttc catatattga ttctaattta
    12301 ttaaaatatt ttttactaca aaaagcagtt ttaggtttaa ttaaatatat tattgtagtt
    12361 cctattataa ctattattcc aataagtata agattgatat ttccaaaatc catagcagat
    12421 acctcctatt aaatttgctt ttcttaatca aagtatatca gtaacacaag tacaaagagc
    12481 atctaaaata ttacaaatat taacaggata gataaaacta tagtaaaaat tgtaataata
    12541 aagcgaacga aaattatcat actaaaacat aagacatgtt ataattgtat tagatagaag
    12601 attaacatac accaaagcac tccttacaat aaagagtgct tatttttttg aaattcatca
    12661 atatataaac tatcaagaac cttattcaac acaccttaaa atcgatttaa atagctcttt
    12721 ttgataacat aatttatatg atataataaa aaaatagaag tgtaccacca atacacttct
    12781 atagctataa ctaagcattc tcttgctggg ggagtgcttt tttcatttct ccaaacaaca
    12841 ttatttactt cattagtaat tatcaaatca atctcattat ctttcaaaat ctctgttgca
    12901 gtacaaatta gattatctaa gtcaaaactt cgagttatct ctagttgttt gttatttact
    12961 tctcttttta gtatataagt tttaaaatac atttatatca ccccttgtat ttactctttt
    13021 ttctctaaaa atatattgat aagtaaatat gcaacaaata aaaaaatctc aatgacacat
    13081 agtgttatag ctataactag aagtgattga tttttccatg cactataagc tatgatgaaa
    13141 agaaatgtaa aagtaaataa tgtataattc ataattttaa ctaagatatg acttgttttc
    13201 attgttaagt acaagtctct ttcatctgca ctatcgtgta attcttcaac aatgcctttt
    13261 cttgaaaaag cattacaaaa attaaagatt gctattacaa ttaaaagaaa tgatgaaatt
    13321 aggaatcttt tatcttttaa aatgcaataa ataactaaac tagcacaaca taacatacaa
    13381 actataatac ccactataaa acttcgttta ctctttactt tcatgttttt tatcctccat
    13441 ttctttattt tcttttaaac aacatagttc ttcaatcgtt gtaccaaaca cttgtgccat
    13501 acgataggca agcataagag aagggctata ttgctctttt tcaatagaaa taattgttct
    13561 gtttgataca tggactaaat cagcgagttg ttgctgtgtt agacccatat ttgttcgaaa
    13621 ttctcgtact tttgttttca ttccataacc tctttctata tgaagctaac ttcatgtgaa
    13681 gttagcttca taatatccta aaatgagtaa aatgtcaatc tcattagata agtattataa
    13741 aacctaaaag aataatatgg taaaaattgg atggaattat ttaccttaat tctcttgttt
    13801 gtaaaacttt attgatatag aatttaacat atacataaat cggcaaaggg gcgcgaatta
    13861 tgaaaattag taaattacca gaagcggaat taaaagttat gagatatatt tgtgaagcta
    13921 acaaggtatt aacttctagg gaattagttg ctgcaatgga agaaaaatat gagtggaatg
    13981 aatcaactac atttacagtt ttgaaaagat tagagcgaag ggagttttta agtacagaga
    14041 aaataggcaa acttacacat tataatatac tagtaaaaga gaaaaaatat ctaaggtttg
    14101 aaacaaagga atttttgaag aacatacata aaaattcaat ttcaagttta atgtcagcgt
    14161 tacatggtga agacgacgaa gtggatgaag ataaattaag tgaactcgaa gaatatttta
    14221 agaatttgaa ataagaaaat gacaaattga tacataataa ataaaatgaa ggtatgaaat
    14281 tataactttt tctaccttca ttttgtttat tattctgaac atgttaagaa aatgaaataa
    14341 gtttgtattt tagttatata aattttaata gaatatgtac agtatatagt agatagaatg
    14401 tataaaaata gaatttaaat aagtagctat tattgcagtg aaatgaatgt ttctaagtat
    14461 atttgggtgg aagaatggtg gaagaaaatt agtgaaatgt aattcttcca ccattcttcc
    14521 acccaaaaaa taaaaactgt tcaataagaa ttaatataca tcaattcagc tgaatgcaat
    14581 caaaatactt aaatgaaagt aatctgaaaa caacataatt caaatcaatt tattcaaata
    14641 aacctcaatt tatcttaaat cttaagaaat atttaagaat taggataata ttttcttaag
    14701 atttatattt tattatatag ttataaggga aagttacaaa aatgtaagcc aaagtaatat
    14761 aacaatttag tcattgttga gaaagggagt gaaagatatt gtataatata gataagtatt
    14821 attatacaat agaggaagtg aaaatatgta caatatatta gtagtagacg atgataaaga
    14881 aattgttgat tcgatagaaa tatatcttaa atcagaagga tttaaaatat ataaagcata
    14941 tgatggaatg aaagctttgg aaataataac agagaatgac attcatctaa tactaatgga
    15001 tataatgatg cctaaattag atggaatcaa agcaactgta aaaatacgag aagaaagaaa
    15061 tattccaata attttaattt cagcaaaaag tgaagataca gataaaataa taggattaaa
    15121 tattggagct gatgattata taacaaagcc atttaatcta ttagagctta tagctagggt
    15181 taaatcaaac ttaagacgat atgtaacttt aggtaattat gaagatacat gtaaagaaat
    15241 tctaaaaagt ggagctttgg agttaaatac actaacaaaa gaagttaaaa ttgatggtga
    15301 aaacataaaa atgactccaa ttgagtataa aataattgaa cttcttttag aaaataaagg
    15361 acgagttttc tcaatagatg agatatacga aaaagtatgg aatgaggaaa gttttaattc
    15421 agaaaataca gtagcagtac atatcagacg aataagagaa aagattgaaa taaatccaaa
    15481 agaaccaaga tttttaaagg tggtgtgggg agttggttat aagattgaaa aattttagtg
    15541 gaaaaattat aaaagaaaag agtttaatat ttaattgcat tttgatttta gtcattttta
    15601 catttacaca aatgttagga attttaatat gttttaattt tttctctgag agtttaattt
    15661 actctatggg gattatgctt ttcttaaact ttattttata taaaatactg acaatgtaga
    15721 tgaggtgggc aacttggaga aatatagagt attaaagtta gtttcattaa tcataatatc
    15781 tatctcattt ccattaacta tattgttggt gacaatagga cttgctgagc ctaaatacaa
    15841 tatacaaaaa acttctacaa agagtgggat ttttgatata tctgatgatt tttatgatag
    15901 taatatattt gacgaaggaa caatggcaag tctattaccc aagtttaagc tatctgtagg
    15961 tggtaaatta actagtaaag aaaaaggtaa attccaacaa gaaggtaaaa gtatagattt
    16021 aagtagtagt gattctgagt atgataaaat catgattaat gaacaagctt ctgaagaata
    16081 tttaagttat ctaaaaaata taaaagtgta tgttattaat acatacacag gagtatttta
    16141 tacaaatacg tcatatgcta gtttatatga ttttaaacaa aaaactaaga gctattgtaa
    16201 tgtagagata ataaataaga taggaaagag ctcatatatt aaaacaataa atggagaaaa
    16261 atttgaactg aataatctga gtctggaact aaatgaagta gatgaaggtt ttgaggcata
    16321 tgtatctttt ccagaagagc caactataga agatggaata gtatatacta attttcaaat
    16381 atttaaacaa gctacagaaa aagtaagatt attttttgta gctagtttaa gtttagcaat
    16441 tatatgttta ttatctataa ttttatatat caaaataaaa ggtgaagttt taaaaagaaa
    16501 taatgtattt ttactaatat acagtaagat acctatggaa tttaatgtaa tattagtatc
    16561 tatttcaatt gcaattttaa ctatatatgc tcttgctgta tcttatcata ttgatgtaat
    16621 tgcattagtt tctttatctt tactgatagt atcaaataat atatttttta taaatgtgca
    16681 attgagctat ttagaaaata aaatgtgtat atttaagaca agtattatag taagagtgat
    16741 tttatggtta ataaaaactg taagggaggt cagtaacgct ataaagaaag tatctttagc
    16801 aaggaaagtt attgttatag tgataatatc tttagcttta atcatggcaa ttagcactcg
    16861 aagtataggt atgggattac tgttttctat atgtattttt ttaggattta caatatatat
    16921 aactaaaaga ctttcatatc ttagttacgt aatagaaggt acagaaagaa taaaaaaggg
    16981 agaattagat tataagataa aaattactgg gaatgataat tttacgtctt tagctgaaaa
    17041 tataaataat attggagaag gtcttgatag agctatagaa gagcaagtaa aaagtgaaag
    17101 aatgaagtct gaccttataa caaatgtatc tcatgatttg aaaactccac ttacttctat
    17161 aataaattat gtagatttaa ttaaaaaaga agaatcaata caaccagagt atataaatga
    17221 ttatataaat gtacttgagt caaagtcaaa aagactaaaa ttattgatag aagatttatt
    17281 tgaagcgagt agagtaagta gtggcaatat agaattacaa attagcaaga ttgatttagt
    17341 gcaactatta agacaaagta taggtgaact tgaagaaaaa ttatctaaaa ataatttata
    17401 tttaaaatta aatgttccaa atgataaggt gtatatatgg gcagatggaa gaagaatgta
    17461 tagagtattt gaaaatcttt tatctaatat agcaaaatat tccttagaag aaactagagt
    17521 ctatattgat gtatatgact atggtgaaaa tgtaaaggta actatgaaaa atatatcttc
    17581 ttatgaatta aattttgacc caagtgagat tatggaaaga tttaaaagag ctgatgaatc
    17641 aaggaatact gaaggaagtg gattagggct tgctattgca agagatttag tagctttaca
    17701 aggtggaaaa ttttatatag aaatagatgg agatttattt aaagcaaatt tagagtttca
    17761 aaaatatgaa gaagaaataa caaatatgga atgagatagt atttaagtat atatattttt
    17821 tttactgtcg aaagctttta ttataatata ttagaatatt tacagtagag aatgaagagt
    17881 aaaaacagag taactttaag tcactctgtt ttttatttaa aatcaataat ataacaactt
    17941 aaattaaaat tgtacacata gttttaaaat aacttataca ataaaacatt atccaaatat
    18001 cacaagataa ttccaaataa atatatagat atcactcctg taataataga aataccaata
    18061 gatttaaact tatatgcaac aagaagtaca atcataaaag atataatttt agggttagct
    18121 atagataaat atagactatc tccattaaaa aatacatctt tagcagttaa ggaagtaagt
    18181 attgctacag gtataaattt catgattttt ttcaaaaaat caggcatctc tttttttgaa
    18241 aaaattaaca taggaagcac tcttggtaga tatgtaacaa tgtacattcc aattataata
    18301 aaaaatatat aattattatt cataagattc ctccttttta cagtaagatt cttctataaa
    18361 gaaaccaatt aaagatgcta aaattgatgc aactattatt actaaattgc ttttgaataa
    18421 tgcatataaa ataacagaaa taatgattga tgatataaat actacaatat aaatcttatt
    18481 ttttatttga gaaactatta aagctataaa catagaagtc aatatgaagc cagaaataga
    18541 actgtctata gatatacttt ctcctaaaaa tgctccaata aaattagcta aaactgatga
    18601 aattaagcag aagaaattaa gataaatagc atttctatca gaccaatttc cagcagtaaa
    18661 tttttcataa ttaactgcaa aagtttcatc tgttatagta tgacaaaatg gcaatataaa
    18721 ttttggactt ttatttttta tgtacatgtt caaattagaa ctcattagaa aatgtcttaa
    18781 gttaactata aatgtagtca aaacaataga tgttacactt gcaccagtag aaatcattga
    18841 agctgcaatg aattgagaac ttcctccaaa tactaaagtt accattagtg ctatttgaaa
    18901 aggtgaaaga ccagattttt gtaatagtat tcctcctact atacctatag gtatataacc
    18961 taagaatata ggaattgaag caataaagct ttcttttaat tgttgagttc tttccacaat
    19021 aaatcactcc ttttgtatta aatgtattaa agtattagta aaacagaaaa atagattaat
    19081 tgtataattg caattataat taaaaataaa tttggattaa tatataaaat actatacaac
    19141 aaatagataa tcttaaacgg ttattaaatt ttatctattt gttattatga tgtaataata
    19201 catattaatc tctataagtt aattactatc tggtgtaatt ttattttaac aacaaaaaaa
    19261 aatacacaca attaaaatat tgtgtgcaat acaattattt tttctcttct aatagtcttt
    19321 ttaatacgct caaaccagct ttaagttctt ctgtactttc tgtagcacat acagctattc
    19381 ttattgcaga aattggtttt tcttttccaa cagcaaaacg ttcagaagca tagacttgta
    19441 caccttcttt aagtgcttgt atctcaaatt tttctgccat tattccatca ggtagaatca
    19501 accatctaaa tatacattct tcatttccca aaagattata tccagataaa tattgattaa
    19561 taatcttgtt tcttcttctt gcagatttac ggcgtgcatt aattaattta tcggcttcac
    19621 ctgatgtaat catgcgataa gcaatttctg ttaaaaaata agattgagat agattaatgt
    19681 tgtataatgc gcttgataat gcctctcgat actgtttagg tgtagagata tatgctagcc
    19741 gtaaactagg tgcaataatt tttgataaac tcgtaatata aattgtttga tttggcagat
    19801 aggaagccac tggatttaaa tgtgtttcat taagtaaact atgaatagca tcctcaataa
    19861 caattaaatt gtatttagat gcaatatttg caatcatttt tcgtccattt tgtgacatta
    19921 tatgtgtagt tggattttga taatctggta ttatgtatag acctttaata ttttcatttt
    19981 tacaagcata taatagtcct tcttcactaa tctcattatc ttcttgttta attggaatta
    20041 gttgaatccc aagcatttta gctgctgtct ttattccagg ataagttaat gggtctacac
    20101 ctattctatc tccatgttga aacaaaccag ctaaaatagc aacaattgca ttttgtccac
    20161 cacttgcagg aagtaagcta tctgatgtag tttcaagccc agctttataa attaatttgg
    20221 caatagcttc tttttgccat ttagcaccat ctctttgtcc atattggaat atagttttaa
    20281 aatctatttc cttaattatg tgtttaaaca aagtattcat ttcttctagc gtgaaatctg
    20341 gattcattgt gcccatttca ataaatgtaa ttttattatt actggacatc aagaatagat
    20401 ttgaacgtgt atcataagat acaaaagttc cacttcctgt aactccactt attagacctt
    20461 ttttttcaca aattttaaaa gctctagaga tagtactcac attaacatct aagaaatctg
    20521 ccaattcacg ttggggtggt aatttagtac ctggtaataa aaatccattg ttgatatctt
    20581 gttctagttg ttctacaagc gccttatata atatttgccc ttttgaaggt ctctttggtt
    20641 tccagttcat aggataattt tcaaaagaat taattggcat aagttttcac ctcacattat
    20701 taatttgatt ttttctttat ctaaaacaat aaattctaaa gatacaaata aaaactgata
    20761 ggaaataatt ctatcagttt ttgtctttta attgatttca aatcttccta taatttttat
    20821 accttcttta tcataaagag ggattgtttt tttaaatata ttaaaatttc tttttcttgt
    20881 atataaaaca gcttcttctg gtgtctttgg ttggttatca caatcgtaca aatttctttt
    20941 ttttaactaa aagcaataat acataaaatt attattgcta atgatactct taatgtggta
    21001 tatagtcata gtgtcacatg tctatcaata gttttttcag taattattgt aacgaatagt
    21061 aggactcata aaatacttag aaatatgttt ttagataaat tttaaatata taatctaact
    21121 tatatctata aattaacact attattctcc aattccattt ctagtttttt tataaattta
    21181 ttaaattctt ctggttgcct ttttccaaac aatactctta caagagctga attgattttt
    21241 ccaaatatat tcctcttgct ctcactttca ataaaaataa gttttgtatt ttctaagtca
    21301 atatgtacta attcatatct agtaatagta ctttctcttt tattgcttgt ttttatctca
    21361 tatactctat ttttttcgaa attagttatt tcaaccttaa atcttttatt atttttttgc
    21421 tgtacaaatg ttcctactgc ttttttctca ttaaaattag gaaaatttag tcttgcagat
    21481 tttgtaaata tattaaatat gtcttttgca gaatatttta ataaaacttc agttttaaat
    21541 gtattcatat cgttttccct tctgtatata aatttaatat ttataagtta atttttaagt
    21601 taaaatagta taatatgcca tattaaatca tgttaaaact atttatatag ctaaaatctt
    21661 acctatataa gtatgtatac tatcatataa aaataaaatc ttaaaataga aagggttaaa
    21721 aacacagttt attataattt ttattgttga gtagatacgt actattatat atgattgagc
    21781 aagtttttca atcataaatt tataaagtat tttgcattaa aatttaaaca aagaattaaa
    21841 ttatttaaga ttatgaataa ctaatacatt tagtaaatta ctaaatatac aaaatgtaaa
    21901 tacttatcaa aatgtataaa tacttatgac atctagttac ttacagggtt taagtagaaa
    21961 aaaatatcaa agtaagtatg gcatgatagt tgcttatata tttatcaaga aaggagttat
    22021 taagcatgga gttgagagat aaacttgtaa acatcataaa tacagaaaat aaaaaagatc
    22081 cattaacaga tgttcaaata gcaaagtttt taagtacaac tagagagaac ataactaatt
    22141 tgagaaaaga acttaatata agtaattcaa ggcaaagaag atatccttat ttaaaatcag
    22201 caatttcggc aatattacaa aagaataaga atatttctgt atcagaaatt acaagggaat
    22261 tgatgacaga aggctttaat atatctagaa gagttgtgga ggaactttta cctaaagaaa
    22321 gtttagaaat ggatgtagta gaggaatctg aagaagaatc gaatgaccca tttgaaactc
    22381 tgataggtaa taaagggagt cttagaaatg ctgtagagca ggctaaatct gctatattgt
    22441 atccaccaaa agggttacca acgttgatta ttggggaaag tggagttggt aagagtttat
    22501 tttctagaca tatgtatgag tttgcaaagc aaaaaaagat agtaaaagaa agctccaatt
    22561 ttgttgtatt taactgtgct gattatagtg acaatccaca attattatta tctttgttat
    22621 ttggatataa aaaaggtgca tttacaggtg ctgaatatga tacaccaggt cttgtagaag
    22681 aagctgatga aggagtttta tttttggatg aaatacatag attgcctcca aaaggccaag
    22741 aaatactatt ttctatttta gataggggaa agtttaggag attaggtgaa actaatgctg
    22801 aaagaaaagt aagtattatg ttgattgggg caactactga aaatgtagag actaatttat
    22861 tattaacatt cagaagaagg ataccaatgc taataacttt gccaccatta catgatagat
    22921 tactaaaaga gaaaatagac cttatataca atatctttca acaagagtgt aatagaataa
    22981 atgcaaaaat atttgtagat aaaaatgtga ttgaaatact tgcactaaaa aagtttagtg
    23041 gaaatatagg acaattacaa aatatgattc aggttctttg tgcaagagct tttatgaagt
    23101 ttataaattc caaagatgaa gatagtgaat cgatagtagt agtagatata aatgaagttt
    23161 taaagcttaa agattctttt aaagatgctg cctttcaaga gattgaatat acagagataa
    23221 gaaaatattt gaaaaatgct atatttatac catttaattt agaagaatca tcagtaaaag
    23281 gaagtctttt aagtgatgaa tatatattac cagaggacat atacaaaaca attgaaaaga
    23341 aatattatga cctaaaatcc ctagacattg aagatataga tatagagaat attttatgga
    23401 cttttatttt aaatagattt gctgacttaa agtttaatct cgatagtaat gaagaaattt
    23461 tttcaatgag tgatttaaat agttttgtaa gtgatagttt agttaaactg gtaaaagaac
    23521 ttatgaatga tatagttgaa aaaaatatga atttagaagt aaataaaaat atgttcaaat
    23581 atctagcaat acacttagaa gaagctataa aaagaattaa gctaaatcaa aagataataa
    23641 atgtaaattt agaaaaaata aagattgact tttcaaaaga atatgaaatt agtaaaagtt
    23701 ttgcaataaa aattgaggaa tcaattggta ttaagattcc agatgatgaa attggattta
    23761 taacactcta cataaagtct gctctaaaaa atgaagtgaa aaaagataaa gtagggttaa
    23821 taataatttc tcatggacgt atagctacag agactgtaaa tgtagttaaa gaacttttag
    23881 gtgtaaagtt tcctgtggct atagatatgc ctttagatga aaaaccaata aatatataca
    23941 ataaggcagt agaactgtca aaaataatag accaagggaa aggcatattg tttttggtgg
    24001 atattggttc acttacaaac ataggtcaaa tagtaaataa gagaaccaat ataagcacta
    24061 aaactattga tagagtagac ctcctaatgg cactagaagc aactagaaaa gtttctatgg
    24121 gagaggaaga acttgatgaa atattttttt ctttgctaaa agataggatg ggatataact
    24181 atgaattaga aaaacacata gataaatcaa atgcaattgt aacattatgt cttactggag
    24241 aaggaactgc taagtatata agtaaaacgt tggaagaaaa gtatgataac actaaatgtt
    24301 atcaaatgag tgcattggat gaaaatttat tttgtaaaat tgaaaatcta aaagagacaa
    24361 acaatatatt agctattgtt gggacaataa accctaagat accaggtata aattttatac
    24421 cctataataa agaacttttc aaaaatttgg atatctatct atcaaaatca aaacaacaag
    24481 atgacagacc agttaaatcg tatgaaagaa tgcttgatga ggatttagtg atttttgaac
    24541 cagatatata ttttaaaaag gatttattag aatatgtatg ttcaattctt ataaataaag
    24601 aatatgtaga aaaagattac ttagattctg ttttacatag agaagaaatg cttccaacat
    24661 attctaaagg agctataggt gtgcctcatg gagattcttc tactgtaaat agtacaaggt
    24721 ttgtttttgt taaactaaag aatcctattg attggggtgt aggtaatgta aatttcatat
    24781 ttatgccagt ttttcaggct aatgataaag agattgttaa aaatgttctt gagatactaa
    24841 aagatgcaga atttatgaac aatgccaata agtgttttga taaagatgct tttagaagga
    24901 ttatatttga taaatttaaa catctgtagc catagcaaaa aaattgagag gagttagagt
    24961 aatgaatgta gatttaatat cattgggttt agaatctaat gattatgaaa gtgttattga
    25021 agaattagga agtataatgt gtaaaaaaga atatgtaaaa gaaacataca taaatgctgt
    25081 cttggaaaga gaaaggacat taccaacagg tctagatatt ggagaaatgt gtgttgctat
    25141 tccacataca gattcaaagc atgtaaatga gtctaatgta gctgtaggga tattgaaaaa
    25201 tcctgtaaag tttaattcaa tgatagaccc aaaagataga cttgatgtag aacttgtatt
    25261 tttattagca gtaaagaacc cagattcaca agtaaaactg ttaaaggatt taatgtcagt
    25321 ttttcaaaat ataaagttat taaaaaatat aaaaaacgca tcaacaaaag aagaagtagc
    25381 taaattattg gattttatag aaatttaatg taggagaatt ttataaataa aaaattaaaa
    25441 tttaaacaat caaagtaagt attatttttt taataggttt aatcttatat aaaataaaaa
    25501 tttagagtga aaaattagga ggaaattatt atgaaacaat ttaatgtatt atcagtttgt
    25561 ggttcaggga cagttacatc atctatggta gcaggtaaat taaaagaagt actaggtaat
    25621 aaggggattt ctattactac aacagaagct agaccaacag aagcactaaa tttagcacaa
    25681 tcaggaagat ttgactttat aacatttacg agtccacttc aaacaggcga ttatggaata
    25741 ccaactataa atgcatttgc ttgcctaact ggtatagggg aagaggcatt ctttgaagaa
    25801 gttttgactg ttattgaagg gatagataag taagttttgg agacgtgaat ttatagtatt
    25861 taaatcaatg atttagatac tataataagc taatattaac taaatatttg tggaaaaaac
    25921 attttatatg ttgtcataaa ttaaaaaatt ataaaaatag tcacttaagt attaaattaa
    25981 gcttataaat atttataagt aggagggaaa aagatgttag aatttatgaa atctataatc
    26041 gatacatttg gttctgcaat tatagttcca attataatat tcataatagc aaagatattt
    26101 aaagtaacta ctaagaaatc gtttctttct gctgtgtatg caggagttgc tttacaaggt
    26161 tttacactga ttttaaattc atttacacca ataataacac cagttatcaa taggatggtt
    26221 gagagtacag gagtaaacct accagttttt gatgttggtt ggcaagcaac atcattggtt
    26281 gcattttcaa caagtgcagg tatgatatat ttaggtcttg gtatattatt acaaacaatt
    26341 ttatttttga taaaatggac agacgtgttt caaccatcag atttatggaa taactattct
    26401 tatatggtat ggggagcaat ggttatagga gtaacaggaa attttccttt aggtatagca
    26461 tgtatggttt tattaaacct atatagttta ttaatatcag agttagttgc aaagagatgg
    26521 tctagttact atagatatcc taattgtaca ataatagcta tgcataatgt tgaagcttct
    26581 gtgtttgcag tatttgcaga ccctatatac aataaattgg gattaaataa aataaaatta
    26641 aatccaaaag aattagagaa gaaattaggg tttttaggtg aaccaattac tttaggtctt
    26701 tttttaggta tgtttatagg tatattaggt aatatgacga gaataaatac tatggaagct
    26761 tggggagaaa taatgaaagt aggtatatct acaagtgcag tgatggcaat tttccctaaa
    26821 gtagcaagta tgtttgctca agcatttgca cctataacag aagcagctag aaagattatg
    26881 caaaaagctg gaaaccgtga gtggtacata gcagtaaatg atgctgttgg gtatggtgaa
    26941 cctgcaactt taatatcagg tcttatatta attccaataa tgcttgtaat agctatggta
    27001 cttcctggta ataaggtatt accagttgtg gatttattgg caattccata tatggttcaa
    27061 ggtttagttg ccatacataa tggtaatata ccaaaagtat tggtttcagg tataatttgg
    27121 tttggattag gattatatgt ttgtacatct acagcaccat tatttacaga tatggctaca
    27181 aatataggtg tagctatacc tgcaggagca atgttaataa caagctttaa tatactagga
    27241 aaacctttga tgggattagt tttctttgca tttctaagtg caaatccaat ttatataggt
    27301 ctttcagttg taatttactt tgttctatgg gcattgttta gaaagaacaa aacaagtatt
    27361 cttgattatt tagaaaaaca agcacttaaa aatgtagaag aagagcctgt agcagtttaa
    27421 gtttataaaa atgaaataag aataattaaa ggagtttata attgatttta tataagtatc
    27481 agataatacc tgagaaatat ttaaatgaaa tatagacttc tttttatttg ataatatttg
    27541 taattataat gcattgtatc tttatagttg agttttctgt ataacctgct atttaaaaca
    27601 tactctttta tatttataca gtaatgtggt ttaattttat aaaatgtaat ctctactggt
    27661 aaaagacttt gtatataagg catttgcctg aataaaccat ttatcttttg tatggcatag
    27721 atattgctat atagaagtat atagcatgaa aggagatatt tatatgggag ataaaatgag
    27781 agcatcagta ttgtatagtg taggtgatgt cagatatgaa atggtagata taccagaaat
    27841 aacagatacg caagtgcttg taaatgtaaa atatgttggg atatgtggtt cagatttacc
    27901 taggtctatg gtaagtggtt tgagtggaaa tacaaaatat ccattgattt taggacatga
    27961 attttctggc gaagttgtta aaattggaga aaaagtaaag catattaatg taggagatag
    28021 agtagctgtt gcaccattag taccttgtgg aaaatgtgat tattgtaatg aaggtaattt
    28081 tggcttgtgt gatgattaca atataattgg aacaagagta aatggagcgt ttgcagaata
    28141 tgtaagagtt ccagaagaac atattttaaa actaccagat acattggatt atgaaactgc
    28201 tgccggaatt gaaccagcaa ctatagctta tcatgggatt tcaaagtcta atattagagt
    28261 aggagatagt gtagttgtgt taggatgtgg tccaataggt cagtttgtta tacaatgggc
    28321 aaaggtgttt ggtgcatcta agattatagc agttgatatt tttgatgaaa aattagaact
    28381 ttctaaactt ctaggagcaa actatatact taactcaaaa gaagtaaatg taatcaaaga
    28441 aataaaaaaa ataacaaatg gtggtgctga tgttgtaata gagactgctg gtagccgatt
    28501 tacacaagaa caatctctat ttgtagcaaa aaagagggga aatatagtgt ttgtaggtat
    28561 atcacacaca gaattaccac ttagtgcaga cgctactgag tgtatattac gtggagaact
    28621 taccttgaaa ggttcttgga attcatatac aagcccttat cctggaagag catggactgc
    28681 aacattggat tttatgggaa aaggtgacat tatttttaaa cccatgattt cacataaaat
    28741 aggtcttaat gaagtgggtg actttttaag taaaatgagc aagagagaaa ttaatttcaa
    28801 taaaatccta gtagaaatat aaaaatttaa taaaaaattc taaaagcaat taaattttat
    28861 aactatgaca ttaaataaaa taaaaataat tttcttaaat aaaatatagg aggaagaaaa
    28921 gtgttagaaa atttaaaaga agaagtatta aaagcaaact tagaattacc taagaaaaag
    28981 ctaattactt atacttgggg aaatgtaagt ggaatagata gagaaaaagg attagtggtg
    29041 ataaagccaa gtggtgtaga gtatagtaat atgactgtag aagatatggt tgtagttgat
    29101 ttagagggaa atatagttga tggcaaatta agaccttctt cagatacccc gactcatcta
    29161 gttttatata aagagtttga agaattgggg ggaatagtac atacacattc aagttgggca
    29221 acaatttggg ctcaaatagg aaaatctata ccatcttgtg gtactactca tgcagattat
    29281 ttttatggaa gtataccatg taccagaaaa atgactagag aagaaatttg caatgaatac
    29341 gaaaaggaaa ctggaaatgt aatcattgaa gaatttatgg gaagaaatcc aattcattgt
    29401 ccaggaataa ttgtaaatga ccacggacct tttacatggg gaaaagatgc aaatgaggct
    29461 gtacacaatg cagtagtttt agaagaagtc gcaaagatgg cttattatac agagttaatg
    29521 agtcctgata atattatgga taaggttctt atgaataagc atttttcaag aaaacatgga
    29581 aaaaatgcat actatggtca aaaatgatta tctggaggtg aattatgcta gactctttaa
    29641 aaggtaaaat tgtggaaata gcaattaaag cagagcatta tggtttatgt aaagaaaaga
    29701 ctggtaattt tagtattaga gataaggata ctggatatat acttataacc ccatcaggtg
    29761 taggaagaga agaattaaaa gttgaacata tttgtgtatt ggatttggat ggaaatgtaa
    29821 tagaagttga gaaaggtatt aagccaagta gtgaggtatt gatgcatatt gaaatataca
    29881 aaacaagaga aaatataaat gccatatcac atactcattc tttatatgca acagcatttt
    29941 cagtagcaaa gaaaccaatt ataccaattg tatatgaatc agttaattat ggcggttatg
    30001 tagatattgc tccatatgaa agaccaggaa ctttaaaatt agctaagagt gtttcaaaat
    30061 tactgataga tacagatgca tgcttattag aaagacatgg gttgacaact gtaggtaatg
    30121 atttagacga agcattatta aaatcaagat atgtggaaga ggtagcagaa atatactata
    30181 ggtctttagt attaaatcaa tttaaagaac ttgaagtagt agatgttgat gagtttaaat
    30241 cttggaaata cccagaagaa ataaagtttt aatctaaata attttcattg aagtggttaa
    30301 ttaaaatata tgtattattt atatcaatta ctatgtttta ttatgttaat taccgtattt
    30361 tgcaaatata tttattacat tttttcaaaa aaatatagaa tccgaaagcc atataaaatt
    30421 gacttgggat tctatacttt ttatttatgc atttttcttt atctgatttt ctggagaatt
    30481 tatatgttca aaatattttt tagtttcaga tactattata ggtgataatg caagtaaagc
    30541 tataaggtta ggtattgcca taagcccatt tacaatatca gcaattatcc aaacaacttc
    30601 taactttaag aaagcaccta ataacaccat agccacaaat acagttctat acccattcat
    30661 gccttttaca ccaaacagaa attcaaaaca tctttctcca taataactcc atcccaaaat
    30721 tgtagtaaat gcaaataatg ttaaactaac tgtaagtaat attggtccaa atgtaggaat
    30781 tgctccgtta aaagctgctt gtgtcataac agctccattt aggtctgaac accacactcc
    30841 tgaaataaca agagagaatc cagtaagagt acagattata atagtatcta taaaagtacc
    30901 tgtcatagat ataagacctt gttccgctgg ccattcagtt ttagcagcag cagcagctat
    30961 tggagcacta cctagaccag actcatttga aaatacacca cgagcgatac catttctaat
    31021 tgccagtgac atagttgctc ctaaaaaacc accagtagca gcagtaggtg taaatgcact
    31081 tttaattatt aacataaaag tttcagggat tttattccaa aaagatatta aaatgattcc
    31141 acagattaca acatatataa ctgccataaa aggtactatt ttagtagcta cattagatat
    31201 acttttaagt cctccaaata caaccaaagc tacaaatact gctaatacaa cccctgtaat
    31261 tctagggtct atcccgaaac tattatttat tgcatctgtt attgaattta cttgagtaaa
    31321 agtaccgatt cctaaaagtg caactagtat accacttata gcgaaaaata ttgcaagagg
    31381 tctccatttt tctcccatac catttactat gtaatacatt ggcccaccag acacttggcc
    31441 atttttatct ttagttctgt attttattgc aagaacacct tctgaatact tagtagccat
    31501 tccaaagaat gctgctatcc acatccaaaa aagtgcacca ggtccaccag ctttgatagc
    31561 tgtagcaaca ccaacaatat taccagtacc aactgtagca gctagagcag tacataaggc
    31621 tgcaaaactt gaaacatcac cactaccttt gttttcagca gagaatatta acttaagagc
    31681 tcttggcagt ttagttattt gaacaactcc aagcttaaca gtaagtagta taccagtacc
    31741 aactaatagt accagtaggg gtggtcccca aataaaagca tcaactttgt ttaaaatatc
    31801 aattagattc ataaaaacac tccctcattt tttttgcttt acataatcaa tagaattttt
    31861 aatgaagtaa ttgacaggaa ataagtataa tttattaata atttctagtg taataaaaaa
    31921 agctaaatct aaaaaagatt cagctctgga tgtacactaa ttagcaacca aaataaaagt
    31981 attagtaaat actgtttttg gtagataatc cctgtccttt tgcctgagag attgagcata
    32041 aaagccttgc cccttcggcg cccataatgg gtctctccag agttccgtaa attttacagt
    32101 cctactttta aaagtacctg agagtgttac tccttcggtg tgctatatag caactcttct
    32161 ataaaatctt aaccggatat tgatttgtca tagcttattg tattaataat attaatataa
    32221 gtttttatgt tttgtcaact aaaaaattaa aaaacaaaga aaaaatataa aaatgtaagc
    32281 ctatttacga attataaact tagaaagatg agtaatatac gtgaaaatga attttgtaat
    32341 acacatacaa atgaagtgta aaataagttc taaataaaaa aataataaaa tcttaaataa
    32401 ttaattagat atgattaaat tatggtaata ttatagttac gatattaaga aaagttctat
    32461 ttagttagat tttaagcgta atatgagatt atgtatagag aaaggatgta tttttagatg
    32521 ggaaaaatat tagtgctagc agaaaaacct tctgttggaa gagatatagc aaaagtttta
    32581 gggtcaaaaa atgaaaaaaa tggttatata gaggggccaa agtatgtgat aacttgggca
    32641 ctaggtcatt tggttacact tgctgacccc gaaagttatg gagaaagata taaatcatgg
    32701 agcttagaag acctgccaat acttcccaag caccttaaga ctgttgtaat aaaaaagagt
    32761 ggaaagcagt ttaatacagt taaatcgcaa atgaatagaa atgatataga tgaaatagtt
    32821 atagcaacag atgcaggtcg tgaaggagaa cttgtagcaa ggtggataat agaaaaatca
    32881 caggtaaaaa aaactataaa acgtctttgg atttcttcaa gtacagacaa agcaataaaa
    32941 gacggatttg caaaattaag aagtggaaaa gaatatgaaa atttgtatta ctcagcaata
    33001 gcacgagcag aagctgattg gattattgga ataaatgcaa ccagagcttt gacaacaaag
    33061 tacaatgcac agctttcttg tggaagagta caaactccta ctcttgcaat gttgcttaaa
    33121 agagaagaag aaataagaaa tttcaaacct aaagagtatt atggattaga attaattgct
    33181 acaaagggaa attcagatat aaaatttatt tggaatgata aaaacaataa ttcttcaact
    33241 tttagtaaag aaaagataga atccacatta aaaaaagtaa aaggtgtaga cataaaaata
    33301 tctgaagtaa acaagtcata taagaaaaaa tattcacctg cactctatga tttaacagaa
    33361 ttacaaagag atgcaaataa aatgtttgga ttttcagcaa aagaaacttt atctataatg
    33421 caaaaactgt atgaacatca taaagtactt acttatccta gaactgattc tagatattta
    33481 acatcagata ttgttggaac attaaaagat agaataaaag ctgtaaatat tagtgattat
    33541 tcaaagactt gtaataaatt attaaaaagc aatattatag ctaataaatc gtttgttgac
    33601 aattcaaagg taacagacca tcatgcaata ataccaacag aacagaaggt attcatgagt
    33661 gattttagtg acaaagagcg aaaaatatat aatcttgtag taaaaagatt tttagcagta
    33721 ctatctcctc cttttgaata tgagcagaca actataagtg caactgtaga aggagaaata
    33781 tttaaggcta agggaaacaa agtaataaat ttaggttgga aagaaagtta taaagatatt
    33841 gaagatgaag atgagtatga aagtatacca aatattttag aaaaagatgt acttaaggtc
    33901 aagggattaa agataacttc aggaaaaaca aatccaccac catacttaaa tgagggaaca
    33961 ttattgactg ctatggaaaa gaatggtcta gggacagttg ctacaagagc agatataata
    34021 gaaaaattat tcaattcatt tttaatggaa aagaaaaata aagatatata tataacatca
    34081 aaaggaagac aattattaga tttagttcca gtagacttaa agacaccaga acttacagct
    34141 tcatgggaaa agaaattatt ggatatttca aagggaaaac ttagtaaaaa tacattcata
    34201 aatgacatga aagattattc aaaagatatt gtactagaag taaaaaatag tgataataaa
    34261 tttaaacatg ataacttaac taaaaataga tgtccagaat gtggtaaatt tatgttagag
    34321 gtaaatggta aaaaaggtaa gatgttgatt tgtgaagata gagagtgtaa tactagaaaa
    34381 actatatcac aagtaaccaa ttcaagatgt cctaactgcc ataaaaaatt agaacttcgt
    34441 ggagaaggtg aggggagaat cttcacttgt agttgcggat acagagaaaa gttgtcgtct
    34501 ttcaacaaga gaaagcaaga agaaaaacag aaggcatcaa aaaaagatgt taatcaatat
    34561 ttaaaaaatc aaaataaaaa tcaagagaca tttaataatc catttgcaga agcattagct
    34621 aagctaaaaa acaaataatt ttaaagttat tattatacac aattataact ttaactgtat
    34681 attagttata tgtactgata taatatagtg tatagtttag gcatgaaagt agggctgtta
    34741 aatggattta agtggcatat ttaaatacta ttgtaaagag tgtgaaaata catggaataa
    34801 ttcgagtgtt gaattatttg agaatataga aacgtatagt aaagattcac aaaaaaagag
    34861 ggaaaaagaa ttagataaat tgctaaatac aatatcagtt catttagaga ggtatccaag
    34921 tgatgctgta ttgagaaaaa tgtgggtaaa aaagggcgag gttttcttac aaaagacatt
    34981 ggaaaaagaa aatattttta agttagaaaa aatggatgta gaggatagaa aaaaattttt
    35041 agatataaca aaacagttta ttagagatgc tagaaaattt gatgatgatt tacctatagg
    35101 tgatattatg caagctatga ggaatgtatg gatttcaaat gcattacaat tattatttgg
    35161 taaagaagta tattattcaa aagctaactt tgcatatagt atgttatatc catatactga
    35221 taattattta gacaatacaa atatagataa aaatgataag attttattta ataactggtt
    35281 agaaaaaagg ctcctgggag aacacattaa atctaaggat tatcatgaaa gtaaagtatc
    35341 taaaatgata gattatattg aaagtgtata ccctagagaa aagtttacag aagtttatga
    35401 atcgttatta ttaatattta aaagtcaagt aaatagttta aaacaacatg gtaaggaaaa
    35461 tcatttgtgt aaagaagatt tattatccat ttctattgaa aaaggaggtt catccgtttt
    35521 agtagatgga tatttaataa gtggattgat gacaaaggaa gaaatagagt tttgtatagg
    35581 atatggattt ttattacaaa tatctgatga tttacaagat ataaaagaag atttaaaata
    35641 caaccataaa actattatta cagagatgtc aaaagagggt actttagata aagttgtaaa
    35701 taaactaata aattttacta ttgagttaat agatagtttt aaaattaata ataaaaataa
    35761 atctgtaata actatgataa agaatgattg cttaatgtta attttatttt ctgtagttta
    35821 taatgctgaa tttttttctg taggatatat aaaagaagta gagaaattta ttccatatac
    35881 aatagattat tcattagaga ttgaagaaaa aataaaagaa aaatttaaaa atatagatgt
    35941 tttaaataat gaaaatgaat ataaagaaat gattgatatt atttgtgcag agtagaaaaa
    36001 aagggagtgt cttagaatag actttttagt ttatgaggca ctctttttgt ataaaatcaa
    36061 atgtattttc atcattttaa taattaaaaa gagcttatcc ctatttgaga aagccctttt
    36121 taatttaata aaaatgtcaa ggttaaacta tttaaatgca gtaataatcc cattatcatg
    36181 taagtttttt atgattgtag ctgcgatagg gaatccaaat aatccagcta ttccaaatag
    36241 ttgagctcca acaaacatac acattaatgt tattaaagga tataggccaa tttggtgtcc
    36301 tactaccttt ggttctaata tttgtctaac aacggttata attatgtata gtattaaaag
    36361 tcctattgct aaattaatat ttccattaat gagtgagata atcatccaag gtgtcaaaat
    36421 acttcctgta cccaagactg gcaaaatatc aacaagtgct atgatgacag atatagtaaa
    36481 tgcattttca acctttagga tagtaagtcc aataagtagt tctatgaatg tcactgatag
    36541 tagtattgca taggctttta gtagttttaa aagagcatta atactgctat tttttatatt
    36601 tattatcata aattgacttt tttctggaaa ttgttttaag ataaagttta ctattttttg
    36661 atagtcaaaa gtaaagaaaa aagaagcaat taaagtaata ataagtttta acataaatgc
    36721 aggtgtttta cttgcaatac tagcaatagc attgagtgca tttgttgaaa tagaagctac
    36781 taaagacatc atagattgac ttatattatc ccaaccaagt attaatgcta ggttaacatt
    36841 aggtgtacta gcatctatct ttgaaaataa agtatttagc gttggttgta tacttgattt
    36901 atatatttca ggaagtctaa aaaatacatc acttacactt gcaaatatct tcacaccaaa
    36961 gctaactaat aaaaatatac acaacccata aaaaattaaa agtattacta tagaaataag
    37021 tgtacgattt aaatttgtat tatttgtaat aagtcttata ataggtctta agatggatgc
    37081 aatgataaaa ctgattacaa aaggcattaa taatggcaat aagaatttta atacaatata
    37141 tacaatactt gttattaaaa ctacatatgt aaatttaatt ataaaattct tttgcttttg
    37201 aatatccata atataaaacc tccaatgtat ttgatattat tctaaatatg gtctttttta
    37261 cagaaaatat actactgtat attgattata aactataaag cttatgtaaa gtaaataaat
    37321 tatgtaaaat ttaggttaat tttgtataaa gagatacttt tatattttac aattaataac
    37381 caaatactaa aaaatatttt aaataaagaa cttaaaattg tgataaaatt aatttataga
    37441 tattaaaaaa agtataatat atggttttta agaggtgcta agatgaaaaa ttttagagat
    37501 ttaggtggga acaaaactga ggatggcaga actgtaaaga agggattatt ttataggtct
    37561 gcaaaattat caaatctaag tgaaaatgat ataaagattt taaaagagtt aaatattaaa
    37621 tatatatttg attatagaag tgatgaagaa gctcgtaaac atccatcaac aataatatca
    37681 aatataaaaa atataagaat accagcaatg agagagctag aagaatcagg aggaagtttt
    37741 ggttctattg aagatatgat tgatggattg tttgaaaaag atggtgcatt taatatgtta
    37801 aataatagtt actataattt gcctataaat aatccgtcat ataaaaaatt agtagaactt
    37861 ataagagact attctaattt accaatatta aatcattgta cagctggtaa ggatagaact
    37921 ggtgtgggga gtgctataat tcttatgatt ttaggggtat cgagagagaa tataatgaaa
    37981 gattatctaa aaagtaatga ttttgcagat aaagagatag aaagatttat agaatataag
    38041 cctaaattta aggacattcc aaaagaaaat ttgaaatata tatttggtgt aaatgaagag
    38101 tatatgaaaa ctgcatttag aagaattgat gaagaataca ttagtgtaga agcatattta
    38161 tatggagaat ttaatttaaa taaagaagaa ataagaaaat taagaaatca atatctagag
    38221 taaaaggtga gtttatgagt ttaaatataa cagcaagaca gataaatata ataaaaatat
    38281 tgttaaattc aaaagataca attagtggta ttgccttaag tcaagagata ggatgttctt
    38341 caaaaactat acaaaatgaa ataaaggata ttaataaaca acttagaaat ggtaaaattt
    38401 tgtcaataag aggagttggt tataaactag aaggaagttt tgatgaggta aatctaaata
    38461 gcaatctcta tgatgatgta gatagagtag aatatataat cagaaaaata ttaaccttaa
    38521 gtaatgaaga aaaaaatact ataaaacttg aagatttagc cgattctatg tatgtaagtg
    38581 tttcaacagt aaaaaatgat ttaaaagaag taaaaagaat gttggaaaag tattcaatat
    38641 cagttaaatc taagcataaa caaggtatat gtgttttaga aagtgaagat aagatattaa
    38701 attgtatagt tgacttaagc aataagagag ataatcaatt gagtttaaat gattttttaa
    38761 atgatgatat aaaggaaaga aaactattaa taaaaaaatt attattagac atattaaatg
    38821 aaaatggatt agtattaact gatatagaat ttaagagtgt gttaaataat atattagtta
    38881 tgttaagcag acataagtat aatgaaaaag aatttataga gaattatata gaaaattata
    38941 ggagcaaaag aagctcaatt ttagaaaatg aacaaaacaa agaaattata ataaattcaa
    39001 taaaaacatt ttgtaaaaat ttaaaattag ctacatcaat agatataagt aatgataagg
    39061 tatttgaaga gtttttatat aagcatatta gtagtttatg taaaaaaata aagttaggta
    39121 taaatcaatc acctataatg gctcaagata taaaaataaa atatccattt gcttttgaac
    39181 tagctaatat agctaaaaag acaatagaaa aagatttgaa gatagaaatt aatgaagatg
    39241 aagttgcaaa catagctcta catataggag gagcagttga aagagcatct tataataata
    39301 aagataaggt tttcaaaact ataatagttt gtacttcagg cataggcaca tcaatgttaa
    39361 taaaagctaa attagagaat atatttaagg aaaaattaga aatactaaag attattcctt
    39421 catacttagt tgaatatata aaagttatag atgttgattt tgtaatatct actgttccta
    39481 ttgaagtagg agatgtgcca gtaataaata tatctccaat tttaagtgag aaagaaatta
    39541 gattaattga aaaatatata gaaacaggaa atatatacct agatttagat ataaaaagcc
    39601 tgtttgatag tgaattgttt tttactgatt tggtgtttaa aaggaaagaa gaagttatag
    39661 attttatggc aagtaaactt gtacaaaagg gctatataga tgaggatatg aaaaaatctt
    39721 actttgagag agaaaaaata gcaacaacag aaatagggaa tatggtaact ataccacatg
    39781 gagctattgg aaaaattttt gataataaaa tagcaattgg tatattaaag aagcctattt
    39841 cttgggaaat atcagatgtt cgtttaataa taatgttagc ccttgataaa gataaaatat
    39901 tagattatga agtaatattt tcaaaaatat ataaaagagt agattctata gcaaaagtta
    39961 taagtatatg tgaaaatagt agttttgaaa aatttgtaaa tttatttaat tagatgggta
    40021 gtattgtata tacacctgta aatttggata atataaaact aaataagata aaaacgataa
    40081 atttctcttt taattaagag aaattttttg actttcaagg atattaatat aaagttaaga
    40141 tataaacata aagcaaataa ataaaaaaga ggtggcaata tgatttatac agtgacatta
    40201 aatccatcaa tagattatat agttaagcta gatgagctaa agacaggaag tacaaatcgt
    40261 gtaaaagaag aatacgttta tccaggagga aaaggtataa atgtatctcg catacttaag
    40321 gaacttggaa atgataatac atctttaggt tttataagtg gttttactgg agaatatata
    40381 ataagaacat tggaagaaaa agaattgaag acagatttta taaagataaa aagtggtttt
    40441 tcaagaataa atgtaaaaat aaaggcgtta aaggaaactg agattaatgg acaaggtcca
    40501 aatatagatg atgaagacat tgatacttta tataaaaaac ttgataagct aaatcaagat
    40561 gatattttaa tattggcagg aagtatacca tctactttag atgaaaaact atacgaaaat
    40621 ataatggcta gattagaaaa aaagaatata aaagttgtag tagatgcaac taaaaatctt
    40681 cttcttaatg ttttaaaata caaacctttt ctaattaagc ctaataacga cgaattagaa
    40741 gaactatttg gtgttaaatt aaattcaatt gaagacatgg taaaatatgc tagaaggtta
    40801 aaggaaatgg gagctataaa tgtcttggta tcaatgggaa aagatggagc attgttgatt
    40861 acagaggaag atgaagtgct tataagtgat gttccaaaag gaaaagtaaa aaattctgta
    40921 ggagcaggtg attcaatggt agcaggattt atatctgggt atttgaatac tgggaaatat
    40981 gattatgctc ttaaattggg agcagcttca ggtagtgcaa ctgctttttc atatgactta
    41041 gccaaaagag aatacattga taaattggta aatgaaatat ctgtaaagaa gttttaaaat
    41101 attaaaaaat atatagaaag gtaattaata tttatgaaaa ttatagattt attagatgaa
    41161 aagtcaatta agttaaattt aaattcaaaa accaaatcag aagcaataga agaattagta
    41221 gatttggtcg caaatagtgg aaatttaaat gataaagaaa actacaaaaa agcaattttg
    41281 gctcgtgaag aaatgagtac aacaggaatt ggagaaggtg tagctatacc tcatgctaaa
    41341 aattcttcag ttactaaagc ttgtatagca gcagcagtgt caaaagaagg tatagattat
    41401 gaatcgtttg acggaagttt atcaaatcta ttttttatga tagctgcacc agacggagct
    41461 aacaatactc atcttgaagt attatcaaga ttatctacaa tacttatgga tgaagacttt
    41521 agaaataaac ttataaattc aagctctgaa aaagaattta aggaaataat agataaaaag
    41581 gaaagagaaa aattcagtga agaatatcaa gatgagaaag tggctgaaaa aaatataata
    41641 gatactaaag agaatgatgc taataagtat cctaaggttt tagcagtaac agcatgtcca
    41701 actggaatag cacatacatt tatggcagct gaaagtttaa ataaaatggc agaaaacaaa
    41761 ggtgtatcaa taaaagtaga aactaatggt tcagcaggtg ttaaaaataa gcttacaaaa
    41821 gatgaaatag aaaatgcaac atgtataata gtggcagcag ataaaaatgt tgagatggct
    41881 agatttaatg gcaaaaaagt cataaaaact aaggtggctg atggtataca caaagcggaa
    41941 gaacttatag acaaggctgt aaatggagat gctccaattt accatggagg agatggaagt
    42001 cacaacgaat caaatgaaga aagtgaaagt ggatttagaa aagtatacaa acacttaatg
    42061 aatggtgtat ctaatatgtt accatttgtt attggtggag ggatacttat agcgatagcc
    42121 tttttacttg atgattatac tattaaccct tcaaactttg gttcaaatac acctatagca
    42181 gcatttttta aaggaatagg agataaagct tttggattta tgttacctgt acttgctgga
    42241 tatatagcat actctatatc tgatagacca gcgtttgttg taggatttgt aggaggtgct
    42301 ctagcaggtg atggtggttc aggcttttta ggtgcactac ttgcaggttt tatagcaggt
    42361 tatttagtag aagggcttaa gaaaatattt agtgtactac cagcttcatt ggaaggaata
    42421 aaaccagtat tgttatatcc tttacttgga acacttttga tgggaattat aatgacattt
    42481 ttagtaatac ctccagttac agcaattaat aatgcaatgg ttggattttt aaatggttta
    42541 ggtggaactt caaaaatagt tttaggatta gtattaggtg gaatgatggc tgtggatatg
    42601 ggtggacctg taaataaagc agcatatgta tttggagttg catcacttga atcagggcag
    42661 tttgaaataa tggcagcagt aatggctggt ggtatggttc cgccacttgc tatagctctt
    42721 gcaactacat tttttaagaa tagatttact aaagaagaaa gagattctgg taaagttaat
    42781 tatgtaatgg gattatcatt tgttactgaa ggagctatac cttttgcagc tggagaccca
    42841 cttcatgtta taccagcttg tgttggaggt tcagcagtgg caggagcact tagtatgttg
    42901 ttcaacgcag ctcttcgtgc acctcatgga ggagtatttg ttataccagt ggttacccat
    42961 ccatttgcat atatattagc tatagctgta ggtgctttgg ttggaatgat gcttttagca
    43021 ttacttaaaa aaccattaaa tcaagaagta tagcaattaa aggatattca agaacttaaa
    43081 atatgatgtt ttataaaaat taatatattg ctgaattatt ttaaaataag gattttatga
    43141 ggctgttata taacgatttg taattgttat cttgacagtc ttttattttt atataagtaa
    43201 aataagtgtg ttttgcttta tttgtattta aattgttttt aagttagaat ataaagaaaa
    43261 ttatatatta ttttaatatt cactcgaact agaaaataat atttgttgta ttttttgtat
    43321 ataaaaatat attgtaatat taaaaaaata atagtaaact gattgcataa aaatgatttt
    43381 tatataaatt ttaaacagaa gaataaattt ctaacgaaat tggatatttc ttctgtaaat
    43441 acatattcaa aaaaagaatt ataagagttt agtcagcagt cgtgtaagta ataaggactt
    43501 tataaatata tagaaatata atgatatgag tataagtaga aaaattttat gatttttaca
    43561 attatttttt ataaaaaagg gaggttatgt ttgttgaatt tacaatcaaa atgggtaaac
    43621 tttttaaagc caacatatgt cagtgatgaa ataaaaagaa aaaaactaca agttataata
    43681 tttttttcta taacttatgg tttatcttat tcactaggtt tattagcaat atgttttaat
    43741 catttaatag attcagaaat tttagctcaa tttatgatga tattgccatt atcttcagtt
    43801 tctattgcaa aattttacac agagggaaga aataatgata aatataattt ctattcatca
    43861 gtaatattat tttttattat ttactttttt atatttatta ttgaatcatt aaagttaata
    43921 agtattaatc aatttcaatt aatgtatctt atgttaattt taataagtag tttatgtgtt
    43981 attgtttatt cttataaaat aacaagttta tatattttta aaaattttaa gataggtatt
    44041 ttgctatttt tttacttttt gttttctcaa attatttttg gattaataat aagtgataat
    44101 caatttgatt ataagaattt cttgaattat attcttcttc ctataatatc attagtatac
    44161 atttatcctt ttttatgtga agagtatggt tggagatctt ttttgcaaag tattttattt
    44221 gatagatttg gcaaaaaaat agggattgta atggtaggca cttgttggag tttatggcac
    44281 ttacctttac aatttacact atatagtcct caaactccaa taattggagc tatagccaat
    44341 ttgatatatg gtattggact ttctatattt ttaggttatg tttatatgaa aactaagaac
    44401 atatggtttt gctctataat gcatgttcta attaatagct taggattaat ttttaatgat
    44461 tctgaaataa ttattaatta ccatagtatt atacaaagat tgatatttat actattattt
    44521 tatactcctt ttctatttac aaaagaatat aagtaagaat tacaattaat ttatataaaa
    44581 taaattttta agtaaatatt tttatagaga gattgttata ttacatatca gaaaaatatt
    44641 aaactaacta aatcaataaa aaagttggtg gataacaatt tataattgtt agcacaacat
    44701 catcttatgt attgaaatct aaaatatcct catttttact tagcataaat actattaatt
    44761 aagaaaataa tatagaaatt ataaatatat ataagtttag tctggtgtat aaaacaagaa
    44821 aactaagtga tttttaattt aactttttat taagcttatt ttttatacta tttataataa
    44881 ataaactcca tgatgggaaa actattacta tttaatatgt aaaggagtat tttaaatgaa
    44941 tgaatcatat tggtttttaa actcaagtcc aaaagaatat aacaaattag gtgaaaatat
    45001 aaaaacagat tgtcttatag taggtggtgg aataactgga ttgacaactg catatttatt
    45061 agcaaaagaa ggtaaaaaag tagtgcttgt tgaggctgat aaaataggat atggaacttc
    45121 tggaaggaat actggtaagg taacttgtca gcatgatata ttttactcta agatagagaa
    45181 aaaatatgga ttagataaag caaaatcata ttataatgca aataatgaag ctttaaattt
    45241 agttgaacaa ataatagaag aaaacaatat aaaatgtgat tttaaaaggg aaacttcttt
    45301 tgtatttaca gaaaaagagg atactataaa ggatattaaa gatgaatatc gtacatgtaa
    45361 aaaaatagga ataaattgtg agtatcatga aactatagaa aatattccat tagatataaa
    45421 gggggctatt agttttacta atcaaggtca atttaaccca aagaagtata ttgatggatt
    45481 ggcaaaagca gcagtaaatt tagggctaaa aatatatgaa aatacaccag tagtagacct
    45541 tgaaaaagga aaaatatgta gggttaaaac aagagaggat aatataatag aagctgagaa
    45601 tgttataatt tcatctcata gtccatggta tgatggattg aatttttatt ttgcaaaaga
    45661 atatgcagag cgtgcttatt taatggttgc agttttggaa aataaattag cagatggtat
    45721 gtttataagt atagatgacc catcaataac ttttagacaa tataatgatg gaagtgaaaa
    45781 tttactgatt tttggaggag gagaccataa agttggtcag ggaggaactg agaaagaaat
    45841 atttgatgat ttagagcatt atggtaaaga agtctttaag gtaaaagatt ttaaggggaa
    45901 atggtctgct caagacaata tgagttttga caatgttcct tatattggtt atatcaacaa
    45961 aagagaagac aatatttatg tagctacagg gttctctaaa tggggaatta ctaatggaac
    46021 tgctgctgga ataataataa aagatttgat aataaataat aattctgatt ataaagatac
    46081 ttttaatcca tccagattag gtagctactt ttcaaaagat tttataaagg aaaatgcaaa
    46141 cgtagcaata aattatgtaa gtggaaaatt aaaaataggt agtggagata tgcctaaaaa
    46201 taatggagaa ggaaagattg ttaatattga tggaaaaaga tatggtgtat ataaggatga
    46261 taatggagat ttttatattg tagacactac atgtactcat ttaggatgtg aacttaattt
    46321 caacagtgaa gaaaaaacat gggactgtcc atgtcatggt tctagatttg actataaggg
    46381 aaatatactt gaaggaccag ctcttaagcc attaaaactt tatggacatg gtgataatga
    46441 tgttaatcct aagttattat aaaattattt ttaggaaggt aaagtgtata tgaataaact
    46501 tttaaagcca ataactatac tattgtatat agtttatatt ttatctgccg tattttttgt
    46561 agcaaacaaa gaatatggaa gtctaggtct ggtagcaatt agtttagttg gtactttcat
    46621 tttgagtttt ataaataagc aaacggaaag attattgagt aaagaattat atataatgct
    46681 tgctttattt ataatgtttt catcattgtt aggtacttgt tttaattttt atgatataaa
    46741 ttattatgat gattttttgc atttatggtc aggtataata tcttgtattg tggctttttc
    46801 tataattaaa tacttttata cacaaagaga gataagtaaa atgagtaaag tgtttttagt
    46861 tatattttta tttatgttta gtatgggagt agcgagttta tgggaaatag gtgaattttt
    46921 aatggatact tttgttggga ctactacaca ggccggaggg ttagaagata ctatgattga
    46981 tatggtagat gctttaatag gcacaattat aactattcct tttatagtaa aaaaatctaa
    47041 tatatagttt taaatttttt atattaatta taatggattt aattaatcat gttgagtttc
    47101 aaggtctata tgattaatta aatccatttt tgttatttat aattattatt gaatatattt
    47161 ttacatataa gatataaggt gatagataga aattgttgga ttatgtaaat aattaatata
    47221 taataccatt atgggcaata aatacaaatc aaatgataat atagtctatt tatgtaaatg
    47281 ttatattgta tactaagtat aatagtaagt tttttgatag tggtgtagaa agtaaaaatc
    47341 tactagccta aattgatgta tggattagtt taggaacagt aattgcatat cttaagtttg
    47401 atgtcatgtt gggctactag aaataggtca tctttttcac ttgaatatct tttctttaaa
    47461 catggagagt atcatatcaa aaacatatga aaattaagtg atttataaga acagtaatat
    47521 tttatatgat agtatagaat agtaataaag tattaggagg aacattgagt gttaaaaaag
    47581 tggtttggta ttgtgaaaaa aagacaaaaa agtgagtcag caaaagaaga aggtgaagta
    47641 atattaaaaa acgaaaaaat attatctgaa gaaaagttga tagatgaaga aggagttgta
    47701 gttaatattg ataatgaaat attaactaaa gtagaagtag taaatgatga taatgaaata
    47761 gaagaaaaaa taatagaaga agattggtta attagtgaaa ataccataaa attagatgat
    47821 aaagaagcaa ttattaatga taaaaacata gaattatgta aaaaagaagt tcaagttgaa
    47881 agtgaaaaaa taggtttaaa taagtttgaa ggacttgacc aaaatgaaaa ttataatcta
    47941 gaaaaaaatg ttattgaaga aaaaaaagta agtgaatgtt tgacagaaga agatttagag
    48001 tacataaaag aaattaaaat aaaaagagga aaaagtataa aagctataaa cttgtatact
    48061 aaagaagagt gggtttttga cactcatata cagtgtagta aaaaactcaa agttccatta
    48121 gggtacataa gagaaaattt aaaatatgga tatatggatt actttggaga tgcaataaat
    48181 tatttaagtg aagtattaaa tatagatgaa tactgcaaaa gtgaatggag ctatctcgat
    48241 aatagcaaat ctccatctga gatatttaat attctaaaca ataaaatatt tagtataagg
    48301 ctttctaatg aaaaaagaaa tgaaattttg acaaatgata aaattgaagc attaaaaatg
    48361 aattatagat ttgaatgtat tgatgaagaa tatgatgaat attttaaaaa atataagtct
    48421 ataatcaaaa gaggtggaaa gaaaaaagtt gaattagtaa ataaaaaagg tgacatttta
    48481 gaaatattta agtctttaga agaatgtgcc atttatttgc aaaaggaaaa gaatgaagtt
    48541 atacaaatgt taaaatatgg agatacaaaa gtaggaagaa actttataag gtatagtttg
    48601 agaagtattt aatttcattt taaattcata agagtttcat ttctgattca cacatttaat
    48661 attattttaa tgtaaaataa taaaggtgaa gtattgcaca attaaaatta aggagggtat
    48721 taatgtctga agaaaaaaat ccaaaagaaa atacattaga tgaatctaaa aattcagata
    48781 atgtaaattc taaaaaagat gatgtgtcag atgaaaaaaa tactgataac aaagttaaaa
    48841 aaagggaaat aaagctaaac aacaaaacac ttaaagctat tgtagcaatt gttgcagtag
    48901 gagctatatg tttaggtgga ggctatgttt ttggcaaaga agctggaaga aaattgcctg
    48961 ctacttcaaa acactataat agcagtgagg tagtagctac tattggggat aaaaaaataa
    49021 caggtgaaat gttaagaaag agaatggagc cattatttta tttaaatgca aaaactacta
    49081 tgactgatga cgaaatacgt tcatatgaat caaatatgat tgaaactatg attacatctg
    49141 atatattatc ctctgaagca gcaaaagaga aaataagtat aactaatgac caactagatg
    49201 ctcagtataa taatttaatg agtagtatag aatcagcaat gggaatgact aaagaagagt
    49261 ttttaaaaca gtttgatttg actgaaaaat atataaaaga tgatatgaaa aaagagctag
    49321 tagcatcaaa atatttaaat gaaaaatcaa aagttactga taaagaagca gagaactatt
    49381 acaataaaaa caagagcaat tatttacaag ttagagcttc acatatttta ataaaaactg
    49441 ttgatgataa aggtaagcaa gttagtagta gcaaaaaagc tgaacttaag aaagaagctg
    49501 aagaaatact taaaaaagcc caagctgggg aagattttgc tactctagct aaaaaatact
    49561 ctgaagatag tagtgcagaa tcaggtggag atttaggttt ctttggtaaa ggtcagatgg
    49621 tggaatcttt tgaaaaagca gcctttgcat tgaagaaggg agaggtatct aacaaacttg
    49681 tagaaagtga ttatggatat catataatta agaaaactga tgaaaaatat cagccatttg
    49741 aagaggtaaa atcagattta gtaagcagtt taacatcaga aaaacaaaac ctacttatac
    49801 aaaatctaaa agaaaaatat aatgttaaaa ttacagataa atatcaaatg aaagctaaag
    49861 aatagataaa gtcaatttat taaaaaaaag aaaaattaac tgtatggata aaagctattt
    49921 ttactcttaa tatagagagt ataaaatagc ttttattatt ttgcaataaa atctatttat
    49981 atatatgaag tgacaaagaa ataacatgca aaaagatatt aaaaagaaat atttttaatt
    50041 tgaatttttt caataaaaat ttacaaaaat gaaaaaacaa acaaaaaaga attgaagatt
    50101 taagttgtta tttaaatata tatatattaa gattttctgc tgaagatact aaaaaaataa
    50161 tatttttcat aattttaaaa ataataataa aaaaatgaaa atacaggcga taatctattg
    50221 agtaaacata gaaaagatga tattataagt atgtgctaaa atggttaaag caatattaat
    50281 attaaattta actataaaac aaaagggggc gtttttttat gtcaagtaca gaaagcgtat
    50341 ctaaaaaaag tggtcatccg aagagttttt ggcttatttg catgacaatt ttgtgggaaa
    50401 gatttagtta ttatggttta acagctttat tggtattatt ttttacagca agtgtagctc
    50461 aaggtggttt aggtctttct actcaagaag caacatccat gtttggctta tttacaggtc
    50521 ttatatatct tacaccatta gtcggtggct ggttagcaga taaagtttta ggtcaacaaa
    50581 aatgtatttc tataggtgca cttttaatag caataggaga tttcgtacta tttgcttcat
    50641 ctacatctat tgcaatggtt tgggtaggtc tatcaataat tattttagga aatggttttt
    50701 ttaaatcaag ttgctcaaat atagttgggg atatatatcc taaaactgat gtgtcaagaa
    50761 aagatgcagc atacagttta ttctatatgg cagtaaatgt aggagcattt atagctccaa
    50821 taatatgtgg attgctttct gataatgtat ttgcagtaag aggagcaagt ggagatatag
    50881 tatcttatgg atataagatg gcatttttaa tttgtggtat aggcatgatg ttaggtatga
    50941 ttatatttac acttcttgca ccaaaattat taaatgaagt cggaaaatat cctgtgacta
    51001 aaggtaataa aggtgaaaaa attgagtatg gaccacttac taagttggag aaaaatagga
    51061 taatagcaat ggttatttta tttttatttg tggtcttatt ctggacagca tactatcaaa
    51121 cacaaagttc ttttatgatt tatgtaaggg ataatgtaaa tagaactcta tttggatttg
    51181 aaatgccagt agcatggctt acatcactaa atgctatatt atgtgtggct ttatgcccag
    51241 tattagctac cctatgggtt aaattatctc ataccaaaag aggtgatttc tctattccag
    51301 ttaaaatggg attaggaatg ataataatgg gtgttgggtt tatagttatg gtatttgcta
    51361 cattagctaa tggtccagat ggaatggtaa aggctagtat attgtttata gtattgactt
    51421 atatatttac aacagtaggt gaattattct tatctcctat aggacttgca atgttcaata
    51481 aattagctcc agctaagtat gctacgttgt ctatgggagc ctggtatcta acaagttttt
    51541 ttgcaagttt attatcagga aagattgctg gttttacagc cacacttggt tttttacaga
    51601 tatttggagg aatagcaaca gttttaataa tatttggttt aatattattg ggaataagaa
    51661 atgtattaac aagattaatg gctatggatt tactaacaaa agaaaaataa ttcatgacga
    51721 attattgtaa ataaatgaat tactttaaat aaaggaagtt acatttaaat ataaaattaa
    51781 atgtaatttc ctctttgatt atgaaaaaaa gctttacaca aatagatatt ataattaaaa
    51841 ttataattgt
//
LOCUS       DAMJVG010000020        48918 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.020, whole genome shotgun sequence.
ACCESSION   DAMJVG010000020 DAMJVG010000000
VERSION     DAMJVG010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 48918)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48918)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48918
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.020"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            212..1429
                     /locus_tag="PC512_001304"
     CDS             212..1429
                     /locus_tag="PC512_001304"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase"
                     /protein_id="HDF2441065.1"
                     /translation="MMNVTLTDVKEARETIKNIVKRTDLLESVKLSEKTGANVFYKCE
                     NLQKTGSFKLRGACNKIASLTDEEKANGVIASSAGNHAQGVALGAKMTGIKSTIVMPA
                     TAPLAKVSATKGYGAEVVLNGAVYDDAYAKAVEIQKETGATFLHPFNDKYVIAGQGTI
                     SLEIFEQLDNKVDTILCPVGGGGIISGVAVAAKALNPNVKIVGVQTANIPSMKESIKN
                     GKVTTAFNDTTIADGIAVKTPGDLTFEIINELVDEIVVVEETEIAESILFMMESQKIV
                     SEGAGAVCTAAILSGKYVPAKDENVVCIISGGNIDINTLYRIIGVALAKEGRRYSFST
                     IMEDKPGNFAELTRIISENGGNILSANQGKLSAGEALGKQSAEFILETIDYDHIARIK
                     KAIEEKGFKIIEL"
     gene            1524..1904
                     /locus_tag="PC512_001305"
     CDS             1524..1904
                     /locus_tag="PC512_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HDF2441066.1"
                     /translation="MKHEVIHTNDAPAALGPYSQAIKAGNLLFVSGQVPLVPETMEVV
                     EGDVQAQTAQSLKNLKAILAESGADFSNVVKTTVFIKDMNEFGAINEVYAEYFGENKP
                     ARACVEVARLPKDVKVEIEVIAVL"
     gene            2188..2670
                     /locus_tag="PC512_001306"
     CDS             2188..2670
                     /locus_tag="PC512_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2441067.1"
                     /translation="MLNFFKKNKSYKLHAVVSGNSINIEKVNDSVFSKKLMGDGVAII
                     PNSNVVVAPCNGKVTVLTESKHAFGMVSDEGVEILVHIGIDTVSLQGEGFKNEVSQGD
                     TVKKGSPIISFEREKINSQGIDCTTIIIVLNHSEFSEINCMVENEVVAGQDTVIEIMK
                     "
     gene            2691..3506
                     /locus_tag="PC512_001307"
     CDS             2691..3506
                     /locus_tag="PC512_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF2441068.1"
                     /translation="MRVVKIFNNNALSTVTNDRKEAILLGLGIGFNKRPGDKVNEDKI
                     EKIYYVQDHMQTKFLELLKNVSPEVMDASQQIISLIPGNEGKFNNKGILSLVEHISFA
                     IDRMKNNVFLPNLMLLDIKMMYSKEFELGVKALEIIYRVCHIHLPEDEAGYIALHFVN
                     LQSNDNLAYDTLKFVKGSIDLIKECYGLELDESSLSTLRFRTHLKFLAQRIFKNEICQ
                     DDKMIEMYDYLINNHPKNKEYLEKLNVYIEKEFRYKLDKPEKIYLLLHLTKIL"
     gene            3559..5109
                     /locus_tag="PC512_001308"
     CDS             3559..5109
                     /locus_tag="PC512_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDF2441069.1"
                     /translation="MKEKLLGGLETFAKAMVQPLMYLSSAGILMVVGVLLTNDMLLGV
                     LPFFKWEPIQIFGSLIYNCIMAIINNLAVIFAIGIPAALAKKEKHKAALIGFMSYIIY
                     LTASNTMLTSLGQLAKESKMLGLIGTGQATILGIQVVDTSVFGGIILGYIAGYVFNRT
                     SNKTFKGALQIYSGANFSFICMFFVSILIGVVSNFIWPLAQQGIASLANVIKDTGTFG
                     LFLYGFLERILVPTGLHHLIYTPFQFSDLGGVLKVGADTVSGAYAIVMTEMNLPVERF
                     SDSIYYMATGFTKMFGYIGIGAAFIYTAYKQNKKKVKATIIPLIITAVLASVTEPLDF
                     MFVFCAPLLFFVHAVIAGLFIALLKIFDVTALCGGNLLVSVIMNTTVGVEKTHWPVMM
                     ILGLAQIIVYFVVFSFLIKKFNYKTPGREDESTATGEEQSKQLNLDAGIENIIDGLGG
                     KENINTVENCITRLRVNVKDESKINEDIINLTPNSGIVRKGKDIQIIFGLHVHEVRRA
                     VEDFLEAY"
     gene            5206..6558
                     /locus_tag="PC512_001309"
     CDS             5206..6558
                     /locus_tag="PC512_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HDF2441070.1"
                     /translation="MIITIVGGGSTFTPGIVKSIALREKELELEEIRLFDIDKKRQDK
                     VAVVVNWILKEDVKTDVKLTVTNCEKEAYTDATFIFAQMRVGKYEMREQDEKIPLKYG
                     CVGQETCGCGGMAYGLRTIQPMIKVIDDVEKYAKKDYWILNYSNPAAIVSEACRKLRP
                     NARIINICDMPIAIIDMIAGSLNINDVHNIRYDYFGLNHFGWFTSIDYKHRDLMEEIK
                     EYIKENKILLPKSYIENLNKSRSTGNRHAVSSWIHVWESVYTMLESFPKYLPNTYLTY
                     YLLSKETVEHSNINRTRANEVMESREKDLFEGVRHYLETGEISEKAFYAGSHGDWISD
                     LAVSIKNDTRSRFLVITENRGAIPNMPYDAMVEIPAYIGKDGPEVIARGPIPLFQQGL
                     MMQQLNSEKLIVEAYIENSYEKALQAFTLNKTIPSMNVAKEILDEMIEVNKEYWPELR
                     "
     gene            6689..7447
                     /locus_tag="PC512_001310"
     CDS             6689..7447
                     /locus_tag="PC512_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2441071.1"
                     /translation="MNIINKIFWQEDRIGMITNNLEADTHSHCMLQLFLGIEDSIEIT
                     VNEKLVKCNCIIVDKNISHSFSARKKVYYSAIIEPTSIYAEQLTSKMNDFGYWICDND
                     GLEKLRQQGTFLISNSSKEQYLRFMEMLNNYLNIPITLKHYDDRITELFNLLHTCNCD
                     NHTISSFADKVSLSASRLSHLFKEQIGIPLKSYILFHQMECAFRELLSGKNVTEASMT
                     AGFDTPSHFAGTVKRMMGMPVSLSLKDSEFLKVY"
     gene            7494..8213
                     /locus_tag="PC512_001311"
     CDS             7494..8213
                     /locus_tag="PC512_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HDF2441072.1"
                     /translation="MNKEYLEETKMLNYNEPQLKLLVSSKNWLELDDFHKIKSIYEFV
                     QNDILFGYNASDMLSATQVLNDGMGQCNTKATLLMALLRAVNIPCRLHAFDVTKDFQR
                     GATSKLISLLAPKYILHTWVEVFYQDRWIALEGVITDKKYLEAIQKKFFNHGGTFKKY
                     AIATNDLKNTSIDWDGKDTFIQKEAIVYDYGIFPSPDVFFSTHSQHMSKLKNFIYVHL
                     IRKIMTKNVCKARNNYIDKNE"
     gene            complement(8337..9737)
                     /locus_tag="PC512_001312"
     CDS             complement(8337..9737)
                     /locus_tag="PC512_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HDF2441073.1"
                     /translation="METQSNNKKGNLIIAIVMTGAFISSLSQTLLSTALPNIMSDFKI
                     TADVGQWLTTIYLLIAGIIVPTTAYLINRFSTRKLFITSMSIFSIGCIIALFSNNFST
                     MLIARVLQAMGSGSLMPLLQVIILYLCPEEKRGAAMSLVGITVGFAPAIGPTLSGWLV
                     DSFGWHSLFLFLSPIAILDVILSFILLRNVGETQKLKLDIPSIVLSSLGFGGLLIGFT
                     NQGNYGWTNIATYLPILIGIMSLILFTLRQLKSKEPFLELRVFKNKPFLISTILIMIV
                     YASMMSATLMIPLYVQSVRGFSALSSGSLMLPGAILMVVLNPIAGRHLDKYGPHALSI
                     LGTGCLFLGTLSFAFLGRDTSLIHVSLMYCIRMIGISMVLMPLTTWGIKTLDRELISH
                     ATAINNTLRQISGAIGSAILITIMTSATKKAHMSSNMLSNIHGIDVAFSIAATLAFTG
                     LIVSICFIKRHQIIRS"
     gene            complement(9741..10649)
                     /locus_tag="PC512_001313"
     CDS             complement(9741..10649)
                     /locus_tag="PC512_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2441074.1"
                     /translation="MKGDNKVTEKQRLIITIAQKIFDQKGFQNTSISDVVKECKMSKA
                     TFYKHFETKESFICEIINYYDEKFLEIIHSINENNDIPASEKLNRKIIAVWKNIFSRT
                     TINTYIRENFSEEQRKATSKLQTKSRANLLNEYKLSLFDNYGDKIEKIIFDLVFLLDA
                     LIHQFIYIIHVQKREINVYFIAKFTIQILDLVVENMDNLNPLIEKSMFLHKQEDEVYF
                     SLHNKSLFFKMIQDIEELIKTDTSLLENPKLLEAIKKLYVEGKNQQYDSLIMDAMIAY
                     LEKEDTLRPKVLLLNSIKNQLKKETL"
     gene            10910..11557
                     /locus_tag="PC512_001314"
     CDS             10910..11557
                     /locus_tag="PC512_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HDF2441075.1"
                     /translation="MKKKICVAIIFALFIVFVEMFIDSSSEGSKIMTAELSKYRKGVN
                     VLSINNIIVANKKYSLPKDYSPQESSEARDAFYKMNKDAQKSGLNLKAFSTYRSYEYQ
                     DRLFKSYVKEHGEKEANRFSAKPGESEHQTGLAFDIGGDDQSCWANKKFNNTKEAKWL
                     YENAYKYGFILRYPEGKENITGYMYESWHYRYVGTEHSKNFAMNNLTLEEYLHIN"
     gene            11881..14520
                     /locus_tag="PC512_001315"
     CDS             11881..14520
                     /locus_tag="PC512_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HDF2441076.1"
                     /translation="MSYKSTYQEVIKNLDSSLSGLSKERAEELLEKNGANELKEADKV
                     PTYKLFLESFKDPLVIILLIAALVQIFLGETVESIIIFAVIIINSVLGVVQTKKAESS
                     LESLKNLSAPNAKVIRDNKKMTIPAKNLVVGDIVFLEAGDYIPADGRLIEAQSLKVVE
                     GMLTGESEPVLKHTEKISEDVSLGDQKNMVFSGAVVVYGRGSFVVTGTGMDTEMGKIA
                     GLLESAENKLTPLQQKIEDFSKKLGVGIVILALLIFIIQVARNYFMAGNGEMTQIILD
                     SFMFSVAVAVAAIPEALSSIVTIVLAVGTNSMAKKQAIIRKLPAVETLGSTSVICTDK
                     TGTLTQNKMTVVDYYMYGTNNDELDKEKVNYSYHAKLLTMVSTLCNDSHITSDGKEVG
                     DPTEVALINYSSKNDLDYDKLRSKYIRINEIPFDSDRKLMSTVNSIYGDYIMFTKGAP
                     DIVFSRCKYALKNGSKVDITDEIIEEYKHKNEEFSNRALRVLAFAIKDVPEEDFIPSI
                     DDEHDMTLVGIMAMIDPPREEVMDAVKEAKSAGIKTVMITGDHKTTAAAIAKEIGIME
                     EGDLALTGKELDALSEEQLYEKLENISVYARVSPENKIRIVKAWQHKNNITAMTGDGV
                     NDAPALKQADIGIGMGSGTDVAKDASAMVLVDDNFASIVNAVEVGRTVYSNIIKSITY
                     LFAGNLGAIVSIVFAVFAGWSNPFTALQLLFINLVNDSLPAIALGFEKSEKNIMNKPP
                     RHPDESILAGGTLKAVAIRGCIIGVVTIIAQYIGLQVSPELGVAMAFSTLILARIMQT
                     LPARSNNQTVIKLGFFSNKYVIGAVLVCLGLYSLTLIPVLRGIFSIPTTFGLYQLGIC
                     LGLALISSILMELNKLINRSEVK"
     gene            complement(14578..15681)
                     /locus_tag="PC512_001316"
     CDS             complement(14578..15681)
                     /locus_tag="PC512_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate aminotransferase family
                     protein"
                     /protein_id="HDF2441077.1"
                     /translation="MKLKINKAIEMQLKKSYAIESGHSEDVFEIDCGEGINTVSYSNK
                     AVEAFNALKFDMIRGYPHSIALKDNIVDYWKDFIALDTDRICLADGSIHVIYLLNRLF
                     IEKGDKVLGYSPQFSEYETDIKMHGATYDYVLLKKEDNFKFNEKEFIEKINPEYKVIY
                     IDNPNNPTGQIIHLSSIENIVKEAAKYDIAVMVDEAYGEYMPKENSAVKLLNNYDNVI
                     ALKTFSKGFGLAGLRAGYAVLPEQLVSPIKKISTPYEVSEISRSIAANLLDDVQFIEE
                     LKEKTKDIKNQLLIPWKNLNIAETSDTVSIMTVEHKNKDIDLQQEFAKLKIRVISGSD
                     FTGLDKNFIRFRMPEEKELPEVIKAFQIIDNIE"
     gene            16042..16863
                     /locus_tag="PC512_001317"
     CDS             16042..16863
                     /locus_tag="PC512_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDF2441078.1"
                     /translation="MGYKLIVTDMDGTLLGNNHKVTDENKTALQKVIKSGINVTLATG
                     RAFDSAKCNVDFLKEDMPIIACNGSLIREQNGNIIYSNKIDTRTCLNILDVLDKYDIY
                     YQCNSIDSMLSKKIEGREDRLSVFLGSETEVIVKDDLREEIFKKDILKFVIIEEKNPS
                     ILDEIRKELRKVQGIKITSSWPNNIEVMNEGVDKGNAVKILAEKMNIDREDIIAFGDN
                     YNDIEMIKFAGLGVAMGNAEELIKQEADYVTDTNQDSGVAKAIYKFLELKESLSS"
     misc_binding    16942..17153
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            17240..18556
                     /gene="argH"
                     /locus_tag="PC512_001318"
     CDS             17240..18556
                     /gene="argH"
                     /locus_tag="PC512_001318"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012101354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HDF2441079.1"
                     /translation="MKLWGGRFRKAENQLMEEFNKSFGYDCVLYKKDIEGSVAHVHMQ
                     VKCGLLTEEEGKSITEGLKGILEDVENGKLVLDGEYEDIHSFTEINLIQRIGDVGKKL
                     HTARSRNDQVAVDMRLYAKEKANDLVGLISEFKATIKDVADKNPVMMPGYTHLQRAQV
                     VTFKHHLMAYYSMFDRDEKRIKNAIEILDESPLGCGALAGTTHDIDRSITCEQLGFKK
                     VVDNFMDGVSDRDYLLELMSDFSIIMMHLSRLSEELILWSSQEFGFVEIDDLYTTGSS
                     IMPQKKNPDGAELIRGKTGRVYGNLFGLFTVMKGIPLAYNKDMQEDKEGFFDSVHTLE
                     MCIQIMDRMIATLKVNEDKMKQAVKNGFLNATEVADYLVKNNVAFRDAHGIVGSIVIY
                     CEDNKKAIEDLTLEELHKFSDAFKEDIYDFIDYESILNKGIKKNLK"
     gene            18805..19143
                     /locus_tag="PC512_001319"
     CDS             18805..19143
                     /locus_tag="PC512_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2325 domain-containing protein"
                     /protein_id="HDF2441080.1"
                     /translation="MNLLVIGGHERMEKDYMVMAKKKGYKTKVYTTMSSKLNNSIGRP
                     DAVVILTSTVSHKMSRTVESQAKKQDILIVRHKNSSKVAFNECLDMVDECLGNCSKCK
                     LKDKQKQKNI"
     gene            complement(19270..20559)
                     /locus_tag="PC512_001320"
     CDS             complement(19270..20559)
                     /locus_tag="PC512_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HDF2441081.1"
                     /translation="MKRNLSLLLICLLIFTSFLGSSNISFADNEPAIVAKHAVLMDYE
                     SGKILYNKDGNSKLYPASTTKVWTACLVLKEVKDLNQVIEIKDLPQIDGSSMYLKNGE
                     SFTVKQLLDALLVHSANDAAFVLARYVGGGNVQKFIDLMNSEAKKIGATNTHFNNPHG
                     LPDPNHYTTAHDMALIAREAMNNDTFRQIVKTKSLKFEATKAYPYERYFVNTNKFLTS
                     HDKITYKGQPINIKYDIVDGIKTGYTDAAGKCLLSSAVKDGRRVIVAVFNSTNADLYL
                     DSRILIDYGFDNFKCATIVDKEKYTDTKKVLFTKQHELIYEPKNSYRIFLEKDESQGN
                     YDTKTELNKIDLPIKKGAKVGTLNVYNNGKLENSIDLIAKNNLDSSLPFFTGNNILMT
                     FVKIIAGILVLLVLFIIASNIKKKKRKKARSKKNMKK"
     gene            20639..21343
                     /locus_tag="PC512_001321"
     CDS             20639..21343
                     /locus_tag="PC512_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HDF2441082.1"
                     /translation="MKKKVKFISFFVLFILIISSIIVYKSLIFKDDIYVVSKKNLPNE
                     KTHVVENEIKGEDNNHNKVTKDIDKNFQNNKITIYISGAVNRPGIVTIESDKRLYDAV
                     ELLGGTTKEADLNGVNLSVRLEDEQHYIIPKIGEATSVTSNDDSNKPNQRNESRGEPK
                     NKSNKNISNESKVNINVATIEELDSLPGVGEATANKILQHREENGQFSSIEEIKNVNG
                     IGDKKYENIKDLICVD"
     gene            21435..22481
                     /gene="selD"
                     /locus_tag="PC512_001322"
     CDS             21435..22481
                     /gene="selD"
                     /locus_tag="PC512_001322"
                     /EC_number="2.7.9.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015617929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:21483..21485,aa:Sec)
                     /transl_table=11
                     /product="selenide, water dikinase SelD"
                     /protein_id="HDF2441083.1"
                     /translation="MKKEQKKLTEMTTAGGUAAKIGPEVLASVLSQLPKNDNIENLLV
                     GLDTADDAAVYKLNDDMALIQTLDFFTPMVDDPYVFGQIAASNSLSDVYAMGGKPLVA
                     MNIVCFPSCHDMDVLAEILKGGFDKVKESGALLVGGHTVDDKEPKYGLSVSGIVSPNK
                     VLSNATAKPGDKLIITKPIGVGVLNTAMKEGMVEQHIADKVIEIMIHLNKYAAMSFEK
                     FDVNSVTDITGFGLLGHTLEMAKASEVSIEIESKHVPIIEGAIEMAQMGIIPAGMYKN
                     MHYVSKDVEVVGNIEVAVQDILYDPQTSGGLLISVKEELAEELVKDMKLNGAIEAKII
                     GSVVPKGEKYITVL"
     gene            22499..23911
                     /locus_tag="PC512_001323"
     CDS             22499..23911
                     /locus_tag="PC512_001323"
                     /EC_number="2.9.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-seryl-tRNA(Sec) selenium transferase"
                     /protein_id="HDF2441084.1"
                     /translation="MIVLSKRELFAMLPSVDEVLSDNRIVEIINEYPRSLVLESVREV
                     IDLKRQFILRLKEDASNSVTIEFGEIIESAIERVKLNYSLSLKKVINATGTVIHTNLG
                     RSLLSEDIKDELWCAASRYSNLEYDLDNGERGSRYSHLTSTIKRLTGAEDVLVVNNNA
                     AAVLLVLSTMAKGGEAIVSRGELVEVGGSFRIPSIMALSGAELVEVGSTNKTHLKDYK
                     EAITEDTNVLMKVHTSNYRIMGFTESVSIEELVNLGKKYKLPVIEDLGSGVFIDLSKY
                     GLSYEPTVLDSIRQGADVVTFSGDKMLGGPQAGIIVGKKEYIEKMKKNQLTRALRVDK
                     LTICALEATLRMYLDETKAIENIPTLKMLTYKIEELEVKANKLFEKITALNLNANINI
                     EDGFSQVGGGSMPLETISTKVISITPEHMNVSSLEKKLRLSEAHIIARVYDNKYVLDV
                     RTIFDDEFDVIVEELRKAFN"
     gene            24025..25908
                     /gene="selB"
                     /locus_tag="PC512_001324"
     CDS             24025..25908
                     /gene="selB"
                     /locus_tag="PC512_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenocysteine-specific translation elongation
                     factor"
                     /protein_id="HDF2441085.1"
                     /translation="MKNVVIGTAGHIDHGKTTLIKALTGRETDTLDEEKKRGISINLG
                     FTYFDLPNNRRAGIVDVPGHEKFIKNMLAGASGIDIVLLVVAADEGVMPQTVEHLDIL
                     SFLNIKNGIVVLTKSDTVDDEFRELVKEDICEKIKGTFLEDAEIIEVDSISKRGIDTL
                     IEKIDKMSDDIEDKNENSPARLNIDRVFSIKGFGTVITGTLIEGKISIEDDLVIYPQV
                     LKTKIRSIQVHGENKDTAYAGQRTAINISNVKVDDIKRGDVLAAPNSLEESMMLDVKL
                     SLVNHLDKGLKHWDRLRLYHGTREILCRAVPLDKELIESGESGYVQLRLEESIVSKKG
                     DTFVVRRYSPMETIGGGVIIDPSPKKHKKFDEKVIEALKIKEKGELKDIIEEYLKRNL
                     KNYPNIKEIMSYSGAHEEDVKRALETLISEDKVFIIGNMYMHINQYNKLKENTIKLLS
                     EYHKKYRLRKGILKEEVRSKIESNFKTREMDILLEKLSTENAIKIENNIVSLLDFEVI
                     LNDKQKEIAKKIEKRLKSCGVSSILTIDEVSEGNHNYAEVLESMIGNKVEKLDDLYIM
                     DKDIYENAKNILINYIKENKEITLGEYRDLIDSSRKNCMIILENFDRNKITKRVENKR
                     ILF"
     gene            26013..28751
                     /locus_tag="PC512_001325"
     CDS             26013..28751
                     /locus_tag="PC512_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation-associated two-component system
                     sensor histidine kinase"
                     /protein_id="HDF2441086.1"
                     /translation="MKNIIPDVKPDIKEREDMSLLFIIMGSVLLLFIIKDIEKYETLL
                     HAIYTIFLVATGVIIFNTTKFKVDSFSTFLGLIFIATGVLECIYLFNSLGIKTKSIME
                     INITISAITDLFPILGVYLSFKFVKDNKQIYSSVILFIATATLTITSLFIISGICDYL
                     GNGKSQYALGVIISIFIIIISIISGIELNSSSNKGKWEYDEKKIFNRIIVIIILSRVP
                     NLLHIVIDNRNVERILSQIIINVALYYLYNYIVSKNIKKTALELHDTNEELTKKTESL
                     KEKNKKLIYETEKIEELKGILMKRESRLQSTLDVAVNSIVVFSKDGEITYANKSFRNT
                     FGDYKEQDKLTDKIKNFNDLIESIHYVFVHEKNAEKLISTSDNKVYQAIFAPLIIASQ
                     TEGVLCVLEDKTKKKEYERKLIEANKRSKDFLESIGDGIVVLEGNNKIYVNNACREIF
                     KNNLESIDFSLVCKSEESIEKRYVIDGEVKYVEMSFSQYTNAGTNKTIIVIRDTTSRK
                     ISQIKLEESQSSYSRFIDILPDGICLLKEDLSINYANKSFLDMLAFTNIDDIKDSNIK
                     LLMNANTEEKMKFTDNMAKVLNENRSILLLEYELINSYDDIVEVELSALPFAIYNTRY
                     IMLIIKDLVHKKYSEQAEKELLERFKTDKIKTEFFANMSHELKTPLNVISSSNQLVDS
                     FYRNEKIKDYNNNIKSHVDLVRQSSYRLQRLINNIIDLTKMESGFYTLKLAKYNIVSV
                     IEDLFMNIEEYALRKDIKILFDTDLEEINVYIDKVEIERIMLNLLSNCIKFTDNGGWI
                     YVSIHYKIDKVIISVKDTGVGIPQDKLELIFEEFSQVDKTLSRNTEGSGIGLAIVKNL
                     VSLHGGDIEVVSEVNKGTEFLISLPMKGFSSEHYTEDKRIYNIQEKIKIEFSDIYY"
     gene            complement(28870..29814)
                     /gene="manA"
                     /locus_tag="PC512_001326"
     CDS             complement(28870..29814)
                     /gene="manA"
                     /locus_tag="PC512_001326"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HDF2441087.1"
                     /translation="MEPLFLKPIFMDRIWGGTALKDKFNYEIDSPTTGECWAISSHKN
                     GDCLIENGKYKGKKLSELWNKNRELFGNTPGDKFPLLTKILDANDNLSVQVHPNDEYA
                     KKNENGELGKTECWYVIDCSDDAEIIIGHNAKSHKEFVNMVNNNEWDKLLRKVNIKKG
                     DFFYVPSGTIHAICKGTLILETQQNSDTTYRVYDYDRTDNSGNKRELHVQKSIDVTNV
                     PHINFDTDYKIVSTSDFKCTTFVSNEFFSVYKLDVFGKCNFTHNTPFSLYSVLDGNGK
                     LIHNSVEYNLKKGMHFILPNDFGDFSFEGNLEIICSHI"
     gene            29987..31348
                     /locus_tag="PC512_001327"
     CDS             29987..31348
                     /locus_tag="PC512_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDF2441088.1"
                     /translation="MELFKAESKKYKKEFLKLLEQWVSIPSFYDRKTVSKDMPFGKGV
                     YDALNWFENLGRENNFKVKNIDNHAVQIEYGNGKEYVDIFGHCDVVNPGEGWDSEPFK
                     LNIIGDKLVARGVSDNKGPMIVNFLALKMIKDLDINLKRKVRLIAGGNEESGFKCIKH
                     YYSKEPYGVCGFTPDAKFPVLNGEKGGAIIKLISNIDDKSLYISGGIEFNTIPDKVYI
                     KNVEKLGKDNICFDINNISINYDNGNYIVYGKGGHSSKPEKSINPILATIKLLSENID
                     EKWTKDLYKLINQDNINGNLFGLNIEGKCGILSMVPTIINIVDGKLEVVLSVRYPEIL
                     TIEDIIKKFNLYMEQNNINKFELIGENLKQANYIDRNSKLVRSLHDIYIKYSGDLKND
                     VRVTSAGSYASEMNNSVIFGCEFPDGSFGNVHSANEFASLDRFITAIGIYAEAIITLC
                     NKI"
     gene            31436..33325
                     /locus_tag="PC512_001328"
     CDS             31436..33325
                     /locus_tag="PC512_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF2441089.1"
                     /translation="MITKKHAIIVKSLSNKDGYMTSNELAIKLDVSTKTIKRYIADLN
                     SVLSKYDLVIASSRGIGYKLSGSKNNIARAVKEANKYIDGFLDDSEESRMSNIICMLI
                     NRNYMSIEAMAEELNLSIAAINKLSSKLKRKLEKYDLVIKSKPYYGSYIHGEEINIRQ
                     LITDYAIKLDEKSKVKVFLDDISENDIHCIESILEKHLREKDTIISDKDFNLLLSKII
                     VSVFRSKRGHSNNINLMDTSYRFHNYYFIENLMKEISDKIGFKLIEDEVIYISNYSGV
                     IAYKGTQGRKNTSEIEERISTVISSALQDIFLISGSDYTKDDEFMVAISDHIKRFLNR
                     ARANVKSNNPLLHQIKEKFPIAFNLAVFLSNKLETEFNLKLDEDELGYIAIHFAASNE
                     RMKKNTSKKICIVCHYGIGTGQLISEKLKQNISDLSVVGVYPVRYLDMAISQDVDLIV
                     STVELKGYEKPVLYIENIFDDSLIENVNKAFYEKEERRKIISNMFDEKAFFSIKASTK
                     EEVIISLSNKLKERDFIEESSIKSIIDRENISSTEIGNLVAIPHTIVKGDKKSIIGVG
                     ILENPIIWDKQEVQLVFMVFFNTKEKHNFSIFKYLYNFIKDEGGVRGIIKICDFNKLM
                     ALIGN"
     gene            33340..33795
                     /locus_tag="PC512_001329"
     CDS             33340..33795
                     /locus_tag="PC512_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2441090.1"
                     /translation="MGTNIFNKEYVFLNVDAKSKVEVLKFISKKAKDLNLAEDESLVY
                     EGLMAREEQFTTNLGESIAIPHTKNDAIENPAVVVLKFNEDVVWNEGEDKVKLAISLL
                     MPGKSKENIHLKLLSSLSRKLINKEFKDSLLKSDNVEEISNLINEALGL"
     gene            33854..34171
                     /locus_tag="PC512_001330"
     CDS             33854..34171
                     /locus_tag="PC512_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HDF2441091.1"
                     /translation="MNKKLVALCACPMGLAHTFMAAEAIEQAAKALGYEAKVETQGAD
                     GVQNELTRDDILGATMIIHAVAITPEGMERFDGCEVYEVELQEAIKNAEGVIKEIEED
                     LGI"
     gene            34196..35458
                     /locus_tag="PC512_001331"
     CDS             34196..35458
                     /locus_tag="PC512_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HDF2441092.1"
                     /translation="MAIKKKVINSSGASTTGGNNVGKSTPSSPTQSKGNGKWKEISKH
                     IMTGISYMIPVLVMGGLIGALSQLIPYAILGLDPSVGIVDAMNSGEFTGFKLSLLNIA
                     QLMSNFGFTLFGFAIPLFAAFCANSIGGKTALIAGFIGGYIANKPVGVPQFVDGQWTE
                     VVPVASGFLGAILIAFIIGYFVKWLNKSIKVSHNWLAFKTTFLIPLIASLACMVLMIF
                     IITPFGGLINESMKNFLTAAGAAGEYVYATALAAATAFDLGGPINKAAGFVALGLTTE
                     NVLPITARTIAIVVPPIGLGLTTLLDKRLVGRRVYDRQFYQAGKTSIFLSFMGISEGA
                     IPFALERPGFVIPLNIVGSVIGAITGIILGAIQWFPESAIWAWPLVDNLFGYIIGIAV
                     GAIFIAVGNIFYRNKLIKDGKLVVDYID"
     gene            35563..36627
                     /locus_tag="PC512_001332"
     CDS             35563..36627
                     /locus_tag="PC512_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDF2441093.1"
                     /translation="MDKIEKVREYFREYDIDGFLINSPTNKFYVGNLFSSSGYVFITK
                     ESQYIIVDFRYFEEIKRKSSLFNVVLMDKTRTHFDIINDICREQNIKEIGFEGNEVSF
                     DLYRSMSNKLSATLKSVDLSTLRETKNEDEIKYIKKACEIVDATFYHIVDFIKVGMTE
                     KQVENEIVRIIKDLGGQKESFDTIVASGLRGALPHGKASEKVIEYGDFVTFDFGAKYN
                     NYCSDITRTICMGTINKELEEIYNIVRKANEECIRVLRPGMTTGEIDKVARDIIGSYG
                     YANNFGHNLGHGVGIMVHEYPALAPESNEVLKEGMIVTIEPGIYVPSLGGVRIEDDVL
                     ITQDGCMRLTTSTKDLIVVS"
     gene            36681..37859
                     /locus_tag="PC512_001333"
     CDS             36681..37859
                     /locus_tag="PC512_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PatB family C-S lyase"
                     /protein_id="HDF2441094.1"
                     /translation="MYNFDDKPDRVSEKCRKWDLNIIRDKFGDIREDFIPMWIADMDF
                     KIPTEIENKFIEAVRRGVFGYTYCYDEFYDSVIGWQKNMHEVNVEKEWITLTYGTVST
                     LHYVVQAFCKKGDSIILNTPVYDPFESSAKKQGVNVICNTLDVVNDRYYINFDKLEVQ
                     IKENKPKLMMFCTPHNPSGRIWTIEEMTRVATICKENNVILVADEVHAEHIHYGTFNS
                     ILKIGKELLENVILLTSPNKGFNLGGLKTSYSIVINKDIRDKFRNKLKQNSITSPNVF
                     GIIGLITAYNECHEWLSGVNEYIKSNYELLETWVNKYNKIKLMKMESSYLAWMDISGL
                     GISASEFTDKLAIDTGVLLEDGSHFVKDGEKYVRINLGTQKENVIEALNRMDLFLKSL
                     "
     gene            complement(38050..39108)
                     /locus_tag="PC512_001334"
     CDS             complement(38050..39108)
                     /locus_tag="PC512_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HDF2441095.1"
                     /translation="MNKKKITFIFVILILALILFSFFRSSSQNTKYSKTSYYLGTVNE
                     VTVFNVKESKSDKILNECDSILRYIDNKMSTHIPGSDVSKINDNAGKKFVRVSDDTFF
                     VVKEAIQYSKLSDGYFDITIGPLSNLWAIGTDKAKVPSDSKIQKLLPLIDYKNIILDE
                     KNKSIKLTKENMKIDLGAIAKGYAADKIVAYLKSEDVKKGLVNLGGNIFTLENGKNDK
                     PFKIGIQDPTSKNGESIGNIETTNKSVVTSGIYERFIEKDGKIYHHMLNPFTGYPFEN
                     NLSSVTIISDKSINCDALSTSTFGLGLEKGMNLINKIDNVDAIFITKDKKVYLTKGIK
                     DNFKLTDKSFSIEKLNKQ"
     gene            39175..39546
                     /locus_tag="PC512_001335"
     CDS             39175..39546
                     /locus_tag="PC512_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HDF2441096.1"
                     /translation="MKKKDILLILGILVVITACYGIINVINSKNAGNIEIYVDNKLYK
                     TVSINAKEEFKIESRGGYNIVKIHDKGVEIVDASCPDKVCVHTGFINKPSQSIVCIPN
                     RVSIKINTNEKNDNQEDIISK"
     gene            39583..40257
                     /locus_tag="PC512_001336"
     CDS             39583..40257
                     /locus_tag="PC512_001336"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HDF2441097.1"
                     /translation="MVNLGNDWDELLKEEFEKDYYLNLRKFLIEEYKTRQIFPNMHNI
                     YEALKHTSYKDTKVLILGQDPYHGDNQAHGLAFSVQPQVKTPPSLLNMYKELKDDLGC
                     FIPNNGYLMPWADQGVLLLNTALTVRAHEANSHKNKGWEIFTDRVISILSEREDPVIF
                     VLWGSNARKKVELIDTSKHYILEAPHPSPLSASKGFFGCKHFSKINEILKKLGKEPIN
                     WQIENI"
     gene            40506..41345
                     /locus_tag="PC512_001337"
     CDS             40506..41345
                     /locus_tag="PC512_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HDF2441098.1"
                     /translation="MNFKKLSNAKVSVMAVVLSVGILSGYSALNKQVTLVVRGEERTI
                     STFSSNVGDLLESQNISYDSNDIVTLDENTKLSNGDKIEVIDVKEKTVVETKDIPFEV
                     TVVEDGSLLKGDSKVKEEGKSGKSELIYKETYHNGKKVEKEFVKKVVKAEPVNKVVSK
                     GTKVEMQVASSRGESSRRMASSSSSSSSSNNGKNMRVVATAYTGHSITATGTKPKWGT
                     IAVDPKVIPYGTKVYIPQFDMVFTAEDCGGAIKGNKIDIYMNDSKTVYNWGRKTIDIR
                     ILK"
     gene            41589..41685
                     /locus_tag="PC512_001338"
     tRNA            41589..41685
                     /locus_tag="PC512_001338"
                     /product="tRNA-Sec"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:41623..41625,aa:Sec,seq:tca)
     gene            41840..42547
                     /locus_tag="PC512_001339"
     CDS             41840..42547
                     /locus_tag="PC512_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA threonylcarbamoyladenosine dehydratase"
                     /protein_id="HDF2441099.1"
                     /translation="MENNFTTRTSFLVGDDGIKKLNNSNIIVFGVGGVGSFTVEALAR
                     AGVGNITIVDFDDVDITNINRQIPALHSTVGRYKVDVMEERILDINPNINIKKIRSLY
                     NKDTSDEILTERYDYVVDAIDMVSSKIHLIETCEKKGLKIISSMGMGNKLDPTKIVVT
                     DIHKTSTCPLAKVMRKELRDRGIKKLKVVYSTEQPIELKKKVMNGRKVTPGSVSFVPS
                     VGGLIIASVIVNELLGQ"
     gene            complement(42689..43525)
                     /locus_tag="PC512_001340"
     CDS             complement(42689..43525)
                     /locus_tag="PC512_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2441100.1"
                     /translation="MRNKIFLSILIIISLLIGCDKKSLLSIHMIDVGQGDSILVQTPT
                     NKNILIDGGDEDSENIIISYLRQKRIKTIDIIIATHPDSDHIGSLDNIIKKFNVNSIY
                     MPEQSTDSKAYQNLINSCTDKNLSIQHLYKNDVLNIDNNINIYVLSPSYIQEESNLNS
                     IVFKLTFNDNSFLFMGDAEEENEKEILHSFKLNNINFIKIGHHGSNSSSSLEFIKKIS
                     PDIAAISCGYKNQYGHPHREVINNLKQNHVSIYRTDRIGDIVFYSDGEIIFTKYNYEI
                     DT"
     gene            43713..44618
                     /locus_tag="PC512_001341"
     CDS             43713..44618
                     /locus_tag="PC512_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2156 domain-containing protein"
                     /protein_id="HDF2441101.1"
                     /translation="MFFKDIELNSKKELDPYFDLVDYEACEYCFSTLYMWQHVYKTGY
                     YIGEDFAVLVGEYEGDSFSILPLAKKDKLPEVVDFVLEYFSKNNKKIYLRGITTEVVE
                     FLKEKYPGRFEYIEERDLFDYIYDAESLRTLAGKKNQKKRNHINYFLKEYAGRYEAKL
                     LDKENFDECLVLMKEWESNKEENNEFDESMDDELIGIKKIFNHYDILKDKVKVFGVYV
                     DGKLEAFSIGELLNPNMALIHIEKANPDIRGLYPFINQQFLVSEFKDVEFVNREEDLG
                     IEGLRKAKLSYHPCRFVEKYSVREA"
     gene            44627..45811
                     /locus_tag="PC512_001342"
     CDS             44627..45811
                     /locus_tag="PC512_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2441102.1"
                     /translation="MEIRYAKEEEIESIKDIWSYCFNDTESFMKYYFNDKYKSENTVV
                     ALDEGKIISSLQLNQYKLLLNSKVYNTSYVVGVSTLPEGRGAGYMNKVMKFTLNELYK
                     KGQLVSILMPIDYRLYRRFGYEHCYDQIEYTINTDDLKNFKSSGKMIKSNLSQIDDLI
                     QIDRTFLNEVNGNVLKDEHYYENLFKEIQSEDGFLYIHEGNEKDGYIVYFLQEDKMFV
                     RELFYKNIDALKSMLKFIYNHNTQCKIVTISTPTIDKIRFILDNPKDSDIKIKPFMMG
                     RVINVKKFIEDIDIEKDINSSFNLLIEDKFIDENNGLFKISIQNKKVSVEQLDKKGAE
                     KPQEDFDIKLDINTLTQLSFSYIDVNEAIFLNDIKDVSEETLETLNCIFSKKNNYINE
                     YI"
     gene            45926..47227
                     /locus_tag="PC512_001343"
     CDS             45926..47227
                     /locus_tag="PC512_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEC/Rec2 family competence protein"
                     /protein_id="HDF2441103.1"
                     /translation="MGVIIIQIRRPLLIILMFVVAISFIITNNTKNDEELNDKIITIQ
                     GVVKGKIEKKRYNQYKVGVFLINDYTKNKNLKIGQKVNITGKFKSLDKMKYDDFDYGR
                     YIKSTGYKGIVYINNYKIIDKNKLYSLIGEIKFYISKTYRYLYKKNSDFINSILLAEV
                     ENLTEEQKEIFTRTGTSHVISISGLHTGILCVIISFLLRGINKLYKLLILSIFITLYC
                     IMVGASPSIIRSIAFVMIFYLSIFIDRKKDGISALSLIGIILIMNNPYVIYNVSFQLS
                     FLATLSILIFYNKINSIIKLSMVSLTISSNILTLPIIYYTFKGIPLLSIIGNLIIVPF
                     VGVIMYLSIASLIVFKVSVVIAKIISFFNSTFIESIFFLLEKISNLSFAYINIENPKF
                     YIVVIYYIGVFFYIFYIEGKEIKEQENELQGYYKECKREKL"
     gene            47181..48224
                     /gene="holA"
                     /locus_tag="PC512_001344"
     CDS             47181..48224
                     /gene="holA"
                     /locus_tag="PC512_001344"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HDF2441104.1"
                     /translation="MNYKDIIRNVKEKNFEKMYLFYGREYYLIENAIKAFKDSLNEGM
                     LDFNLDIIDGKEIVLNQLISSIETLPFMDDRKIVIIKDFELLKGKKKNFTDSDEKYLI
                     EHLDNIPDTTTIVFVVYGDVDKRKSLVKKIGNNGIVFDCDKLSDMDLFKWIKKSFALN
                     DVIIDNSQIMYFIEQEGYRDKSSEKTLSDLENEINKISSFVGKGNNVTNDVIDKLSQK
                     KVENDIFKLIDYIGEQNASNAMKILNDMIQEGESVLGIFSMIARQFKIIMQVRQLQLD
                     GYSTKLIADKLKMHQFVVGKALKQTKNFSDDIIVEILNYILESDYKIKTGLIRDTLAV
                     EMLVSRYCKREAI"
     gene            complement(48411..48677)
                     /gene="rpsT"
                     /locus_tag="PC512_001345"
     CDS             complement(48411..48677)
                     /gene="rpsT"
                     /locus_tag="PC512_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HDF2441105.1"
                     /translation="MANIKSAKKRISVIEKKTALNRVRKSQIKTAIRRFEDAVAAGNR
                     EDAVAKFQYAQKRIYQVASKGTIHKNAAARKVAKLAQKLNGMNA"
BASE COUNT        19201 a         5279 c         8343 g        16095 t
ORIGIN      
        1 agaatgtaaa aaatattttt aaattatcat ttaatgtaat ttaaatgaat tgaagatata
       61 tgtttattgt atgcaattgt tgtattttta ggttttttgt gattaattaa aaaattataa
      121 aaatcgttta catgttgatt tttaaaaaaa aaagatatag aattatatag aaagtaataa
      181 acaaaaattg gatttacggg agtggaatga aatgatgaat gttaccttaa cagatgtaaa
      241 agaggctaga gagaccatta agaacatagt aaaaagaact gacttacttg aaagtgttaa
      301 acttagcgaa aaaacaggag caaatgtgtt ctataaatgt gagaatcttc aaaaaacagg
      361 ttcttttaaa ttaagaggag cttgtaacaa aatagcgagt ttaacagatg aagaaaaggc
      421 aaatggagtt atagcttcaa gtgcagggaa tcatgctcaa ggagttgcat tgggagcaaa
      481 aatgactggt ataaaatcta caatagtaat gccagcaact gcgcctttag caaaagttag
      541 tgcaactaaa ggttatggag cagaagtagt tttaaatggt gcggtttatg atgatgcata
      601 tgcaaaagct gttgaaatac aaaaagaaac aggagcaact ttcttacatc cattcaatga
      661 taagtatgtt atagcaggac aaggaactat atctcttgaa attttcgaac aattagacaa
      721 taaagttgat actatactat gcccagttgg tggaggagga atcatctctg gtgttgctgt
      781 tgcagcaaaa gcattaaatc ctaatgtaaa aatagtcggt gttcaaactg caaatatacc
      841 ttcaatgaaa gagtcaataa aaaatggaaa agtaacaaca gcatttaatg atactacaat
      901 agctgatggt atagctgtta aaactccagg agatttaact tttgaaataa taaatgaatt
      961 ggttgatgaa atagtagtgg ttgaagagac agaaattgca gaatcaatat tatttatgat
     1021 ggaaagtcaa aaaatagttt cagaaggtgc tggtgctgta tgtacagctg ctatattaag
     1081 tggtaagtat gtaccagcaa aagatgaaaa tgtagtttgt ataatatctg gtggtaatat
     1141 agacataaat acgttatata gaataatagg tgttgcttta gctaaagaag gaagaagata
     1201 ttcatttagt acaattatgg aagataagcc aggaaacttt gctgagttaa ctagaataat
     1261 aagtgagaat ggtggaaaca ttttaagtgc taatcaaggt aaattatcag caggggaagc
     1321 tctaggaaaa caaagtgcgg aatttatatt agagacaata gattatgacc atatagctag
     1381 aataaagaaa gctatagaag aaaaaggttt taaaattata gaattataat aaaaagtgta
     1441 tataatatac aagaaaaata gtataatagt gtatgaagat acattttatg tgtattagat
     1501 taacgaatta ggaggatttt aaaatgaaac atgaagtaat acatactaat gatgcaccag
     1561 cagctttagg accatattct caagctataa aagctggaaa cttgttattt gtatctggac
     1621 aagttcctct tgtaccagag actatggaag tagttgaagg agatgtacaa gctcaaactg
     1681 ctcaatcttt aaaaaatctt aaagctatat tagctgaaag tggagctgat ttttcaaatg
     1741 tagttaagac tacagtattt ataaaagata tgaatgaatt tggggctata aacgaagttt
     1801 atgctgaata ttttggagaa aataaaccag caagagcttg tgtagaagtt gctagattac
     1861 caaaagacgt taaagttgaa atagaagtaa tagctgtatt ataaaaatac aatattttta
     1921 atttgaaaag gctgaaaaac tatattctag tgattcagcc tttttataaa aaaataaatc
     1981 acaataaaga acatgataaa tattgtcgaa ttaaaaaata aaattaaaat aaatattgca
     2041 atatttttga gaaggtttta taatgagtat ataatttgaa acgtgtaact attaaattag
     2101 gcatgagttc ttggatattt ttatcctgag gattcatgcc ttttttgtat tgaaattcaa
     2161 aaatctattt aataaggagg aagtactgtg ttaaattttt tcaagaaaaa taaaagctat
     2221 aagttacatg cagtagtgag tggtaacagc attaatattg agaaagtaaa cgattctgtg
     2281 ttttcaaaaa agttaatggg agatggagtt gcaattattc ctaatagtaa tgttgttgta
     2341 gccccttgta atggtaaagt aactgtgctt acagaatcaa agcatgcctt tggtatggtc
     2401 tcagatgagg gtgttgaaat attagtccac ataggaattg atacagttag tttacagggt
     2461 gaggggttta aaaatgaagt gtctcaagga gatactgtta aaaaaggtag tccaataata
     2521 agttttgaaa gagaaaaaat aaattctcag ggaattgatt gtacaacaat aataattgta
     2581 ttaaatcata gcgaattttc agaaataaat tgcatggtag aaaatgaagt tgttgcaggg
     2641 caagatactg ttattgaaat tatgaaataa tagaaaggga ttaattcaat atgagagtag
     2701 taaaaatctt taataataat gcattatcta cagtaactaa tgataggaaa gaagctattt
     2761 tactaggtct tggtataggt tttaataaac gtccaggaga taaagttaat gaagataaaa
     2821 tagaaaagat ttattatgtt caagaccaca tgcaaacaaa atttttagaa ttattaaaaa
     2881 atgttagtcc agaagtgatg gatgcttcac aacaaattat aagtcttata ccaggaaatg
     2941 agggaaaatt taataataaa gggatattat ctttagtgga acatattagt tttgcaatag
     3001 atagaatgaa aaataatgtt tttttaccta atttaatgct tttggatata aagatgatgt
     3061 attcaaaaga gtttgaatta ggagtaaaag ctttagaaat tatatataga gtatgtcata
     3121 tccatttgcc tgaagatgaa gcaggttaca tagctttaca ttttgtcaat ttacaatcaa
     3181 atgataattt ggcatatgat actttaaaat ttgtaaaagg tagtattgat ttgattaaag
     3241 aatgttatgg attagaatta gacgaatcga gtttaagtac attacgtttt agaactcatc
     3301 ttaaatttct tgctcaaaga atttttaaga atgaaatttg tcaggatgat aaaatgattg
     3361 aaatgtatga ttatttaatt aacaatcatc ctaaaaataa agaatattta gaaaagttaa
     3421 atgtatatat tgaaaaggag tttaggtata aattagataa acctgaaaaa atttatctac
     3481 tactacacct aacaaaaatc ttataagaat gagatgaatt agtaatagaa atatatataa
     3541 ttttaggggg ggataagatt gaaagaaaaa ctacttggag gactggaaac atttgcaaag
     3601 gcaatggttc agccattaat gtatttatcg agtgcaggaa tattaatggt ggtaggtgta
     3661 ctacttacaa atgatatgtt attaggagta cttccatttt ttaaatggga gccaattcaa
     3721 atatttggaa gcctaattta taactgtata atggctatta ttaataatct tgctgttata
     3781 tttgctatag gtattcctgc tgcactagca aaaaaagaga agcacaaagc agcgttaata
     3841 ggatttatga gttatataat ataccttaca gcttccaaca ctatgttaac atcactaggt
     3901 caactagcaa aagaaagcaa gatgcttgga ctgataggga ctggacaagc tactatttta
     3961 ggtattcaag ttgtagatac aagtgtattt ggtggaatta ttttagggta tatagctgga
     4021 tatgtattta atcgtacaag caacaaaaca tttaaaggag ctttacagat atactcggga
     4081 gcaaatttta gttttatatg catgttcttt gtatccattt taattggagt tgtgagtaac
     4141 tttatatggc cattagctca acaaggaata gcttctcttg caaatgtcat caaagataca
     4201 ggtacatttg gtttattctt atatggtttt ttagagagaa tattagtacc aactggactt
     4261 catcatttaa tttatacacc atttcagttt tctgatttag gaggagtgct taaagttggt
     4321 gcagatacag tttcaggagc ctatgctata gttatgacag aaatgaattt accagttgag
     4381 cgtttctcag atagtatata ctacatggca actggattta caaagatgtt tggttatata
     4441 ggtataggag ctgcctttat ttatactgca tataagcaaa ataagaagaa ggttaaggca
     4501 acgattattc cactaataat tacggcagta ttagcctctg taacagaacc attagacttt
     4561 atgtttgtat tctgtgcacc acttttattc tttgtacatg cagttatagc tggtcttttt
     4621 atagctttat taaaaatatt tgatgttact gcattatgtg gagggaactt attagtatca
     4681 gttataatga atactacagt aggcgtagaa aaaacacact ggccagtaat gatgatatta
     4741 ggacttgcac aaattattgt atattttgta gtatttagtt ttttaattaa gaaatttaat
     4801 tataaaactc caggtcgtga agatgagagt acagctacag gcgaagaaca atcaaaacaa
     4861 cttaatttag atgcagggat agaaaatata attgatgggt taggcggaaa agaaaatatt
     4921 aatacagtag aaaattgcat cactagatta cgtgttaatg taaaagatga aagtaagatt
     4981 aatgaagata taattaattt aacgccaaat agcgggattg taaggaaagg aaaagatata
     5041 caaataattt ttggacttca tgtgcatgag gtaagacgtg cagtagaaga ttttttagaa
     5101 gcttattaaa gatatatatt tatatagcaa gggtaaataa cagctttaag tgctgtttac
     5161 tatttattaa agatacatat aatttataga ggaggaataa ttattatgat tattactatt
     5221 gttggtggag gaagcacatt tactccaggt attgttaagt caattgcatt aagagaaaaa
     5281 gagttagagc ttgaggaaat tcgtttattt gatattgata aaaaacgtca agataaagta
     5341 gctgtagttg tcaactggat actaaaagaa gatgttaaaa cagatgttaa actaactgta
     5401 actaattgtg aaaaagaagc gtatacagat gctacattta tatttgcaca aatgcgtgtt
     5461 ggtaaatatg aaatgcgtga gcaggatgaa aaaattccat tgaaatatgg ttgtgtaggt
     5521 caagaaactt gtggttgtgg agggatggca tacggactgc gtacaataca accaatgata
     5581 aaggttattg atgatgtaga gaaatatgct aaaaaagatt attggatatt aaattactct
     5641 aatcctgctg caatcgtttc tgaagcttgt cgtaagttaa gaccaaatgc aaggattata
     5701 aatatctgtg atatgccaat agctattata gatatgatag cggggtcatt aaatatcaat
     5761 gacgttcata atatacgcta tgattatttt ggtctaaatc attttggctg gtttacttca
     5821 atagattata aacatagaga cttaatggaa gagattaagg aatacataaa agaaaataaa
     5881 atattattac caaaatctta tatagaaaac ttaaataaaa gtcgtagtac aggaaatcgc
     5941 catgctgtaa gtagctggat acatgtttgg gaatctgttt atacaatgtt agaaagcttc
     6001 ccaaaatatc tgccaaacac ttatttaaca tactatcttt taagtaaaga aacagtggaa
     6061 cattcaaaca taaatcgtac tcgtgcaaat gaggttatgg aaagccgtga aaaagactta
     6121 tttgaaggtg tgagacatta cttagaaact ggagaaattt ctgaaaaagc attttatgca
     6181 ggttcacatg gagattggat tagtgatttg gcagtttcaa ttaaaaatga tacacgtagt
     6241 cgttttttag ttataactga aaatcgtgga gctataccaa acatgccata tgatgcaatg
     6301 gtagaaattc cagcatatat tggtaaagat ggtccagaag ttattgctcg aggtccaata
     6361 cctctatttc aacaaggatt aatgatgcaa caacttaaca gtgaaaaatt gatagtagaa
     6421 gcttatatag aaaatagtta tgaaaaagct ttacaagcat tcacattaaa taaaactatt
     6481 ccaagtatga atgttgctaa agaaattttg gatgaaatga tagaagttaa taaggaatac
     6541 tggccagaat taagatagta ggataaaaga aagggttttt atttaatcat tagatatgtt
     6601 ttcagagtct tttatcaaaa tgtattcaca aacatatggc aatatattaa aataaagagt
     6661 gatattttta gaagaatggg gtgatgcaat gaacattata aataaaattt tttggcaaga
     6721 agataggatt ggcatgatta caaataattt agaggcagat acacatagcc actgtatgtt
     6781 acaactgttc ttagggatag aagacagcat tgaaataaca gttaatgaaa aattagttaa
     6841 atgtaattgt atcatagtag ataaaaatat ctctcattca ttttcagcaa gaaaaaaagt
     6901 ttattactct gctattattg aacctacatc tatatatgca gaacagctta cctcaaaaat
     6961 gaatgatttt ggctactgga tatgtgacaa tgatggatta gagaaattac gtcaacaagg
     7021 aacttttttg atatctaact ctagtaaaga acaatattta agatttatgg aaatgcttaa
     7081 taactatttg aatataccta taactctcaa acattatgat gacagaatta ctgaattgtt
     7141 caatttatta catacttgta attgtgataa tcatactatt tcaagttttg cagataaagt
     7201 gtctctatca gcaagtagat tatcacatct gtttaaagaa caaataggga tacctttaaa
     7261 aagctatatc ttatttcatc aaatggagtg tgcttttaga gaattacttt ctggaaaaaa
     7321 tgttaccgaa gcttctatga ctgctggatt cgatactcca tcacactttg cagggacagt
     7381 taagcgaatg atgggaatgc ctgtttcttt atctttgaaa gatagcgagt ttttgaaagt
     7441 atattaaata ttctcgttat ataatgaagt tgtactaaga aaggggcttt gttatgaata
     7501 aagaatattt agaagaaaca aaaatgttaa attataatga accacaactt aagcttttgg
     7561 tatcatcaaa gaattggttg gaattagatg attttcataa aataaaatct atttatgagt
     7621 ttgtacagaa tgatatttta tttggatata atgcttctga tatgttaagc gcaacacagg
     7681 tattaaatga tggtatggga caatgcaata caaaagctac tcttttaatg gcattattac
     7741 gtgcagtgaa tatcccttgt aggcttcatg cttttgatgt aacaaaagat tttcaacgag
     7801 gagctacatc caaattgatt tcactattag caccaaaata tattcttcat acttgggtag
     7861 aggtatttta tcaagatagg tggattgctc tggagggtgt cataactgat aaaaaatatt
     7921 tagaagcaat tcagaagaaa ttttttaatc atggtggaac gtttaaaaag tatgcaatag
     7981 ctacaaatga tttgaaaaat acatctattg attgggatgg taaagatact tttatccaaa
     8041 aagaagctat cgtgtatgat tatggtattt ttccatcacc agacgtattt ttttctactc
     8101 attcacaaca tatgtcaaaa ttaaaaaatt tcatatatgt acatcttatc agaaaaataa
     8161 tgacaaaaaa tgtatgtaag gctagaaaca attatattga taaaaatgaa tgagtgttta
     8221 agaggtaact atataggaaa tatatagaat aattaaaact gtactggtta aaatgaataa
     8281 aaaggagtta tcacagagca aacttaaatt gttcatagga taactccttt tctgtattaa
     8341 cttctaataa tttgatgtct ttttataaaa catatagata caattaaacc agtaaatgca
     8401 agagtagctg ctattgaaaa tgcaacatct attccatgaa tgttagacag catgtttgaa
     8461 ctcatatgag ctttcttagt agcacttgtc attatagtaa taagtatagc agaacctata
     8521 gctccagata tctgacggag tgtgttatta attgctgtgg catgagatat aagttctcta
     8581 tctaatgttt taattcccca tgtagttaat ggcattaaaa ccattgaaat accaatcata
     8641 cgaatacaat acatcaatga cacatgaatt aaagatgtat ctctgcctaa aaaagcgaag
     8701 gataaagttc ctaaaaacaa acatcctgtt cctaatattg atagagcatg aggtccatat
     8761 ttatctaaat gacgtcctgc aattggattg agtacaacca tcaatatagc accaggtaac
     8821 attaatgaac ctgaagataa tgcagaaaat cctcttacag attgaacgta cagaggaatc
     8881 attaatgtag cagacatcat tgaggcatat acaatcataa ttaatattgt agaaataaga
     8941 aatggtttat ttttaaaaac cctcaattct aaaaaaggtt ctttagattt taattgacgc
     9001 aatgtaaata aaattaatga cataattcct attaatattg gtaaatatgt ggcaatatta
     9061 gtccacccat aattaccttg attagtaaat ccaattaata aaccaccaaa acctagagat
     9121 gatagtacta ttgaaggtat atctaatttt agtttttgag tttccccaac atttcttaat
     9181 aaaataaatg atagtataac atctaatata gcaatagggg aaagaaacag aaataaacta
     9241 tgccaaccaa atgaatctac taaccatcct gataaagttg gacctattgc tggagcaaat
     9301 cctactgtaa taccaactaa actcatagct gcaccacgtt tttcctcagg gcataaatag
     9361 agtataataa cttgtaaaag tggcattaga gaaccagaac ccattgcctg caacacacga
     9421 gcaatcaaca tagttgaaaa attattagaa aaaagtgcaa taatacatcc tatagaaaag
     9481 atagacattg atgtaataaa taactttcta gtactaaatc gatttattaa ataagctgtt
     9541 gtgggtacaa taatacctgc aataagtaga taaattgttg ttaaccactg accaacatca
     9601 gcagtaattt taaaatctga cattatatta ggtaatgctg ttgacaatag tgtttgactg
     9661 agagaactta taaaagcacc agtcattaca attgctatta ttaaatttcc ttttttattg
     9721 ttactttggg tttccataat ttataacgtc tcctttttta attgattttt aatgctgttc
     9781 aataaaagta cttttggtct taaagtgtct tctttttcta aatatgcaat cattgcatcc
     9841 ataattaaag aatcatattg ttgatttttt ccctcgacgt ataatttttt tattgcttct
     9901 agtaatttag gattttcaag gagagaagta tcagttttga ttagttcttc tatatcttgt
     9961 atcattttaa aaaatagcga tttattatga agggaaaagt aaacttcatc ttcttgttta
    10021 tgtaaaaaca ttgatttttc aattaaagga tttagattat ccatattttc tacaactaaa
    10081 tctagaattt gtatagtaaa tttggcaata aagtatacat ttatttctct tttttgtaca
    10141 tgaataatgt atataaactg atgaattaga gcatccaata agaaaactaa atcaaatata
    10201 attttttcta ttttatcacc atagttatca aataagctta atttgtattc attcaataag
    10261 ttagctcgtg attttgtttg caatttactt gtagccttac gttgctcttc agaaaaattt
    10321 tctcttatat aggtatttat ggtagttcta gaaaaaatat ttttccatac agcaattatc
    10381 tttctgttta acttttctga tgctggaatg tcattatttt catttatgga atgtataatt
    10441 tctaaaaact tttcatcata ataattgatt atttcgcaga taaaactttc cttagtttca
    10501 aaatgcttgt aaaaagtagc tttagacatt ttacactctt ttacaacatc cgatattgaa
    10561 gtattttgaa aacccttttg gtcaaaaatt ttttgtgcaa tagttataat gagcctttgt
    10621 ttttctgtca ctttattatc tcctttcacg caaaaacgtt tagtactata gagtacctac
    10681 aagttttaat aaatatatta tacatcattt ggaaaaaaaa tcaatatata gactgtaata
    10741 tgaaattttt gaaaaatttg ttgttatttt tagtcgtata aaaaagaaac ttaagagttt
    10801 cttaagaatt gtttaaagaa gttgcaataa attagtggta tgattatagt atgaaagaga
    10861 atgtcttgaa atttttctgt atcaaattcc aattatggag gtgtagtata tgaaaaagaa
    10921 aatttgtgta gcaataattt ttgctctatt tatagttttt gtagaaatgt ttattgatag
    10981 ctctagcgaa ggaagtaaaa ttatgacagc tgaattaagt aaatacagga aaggcgtaaa
    11041 tgtattatca ataaacaata ttatagtagc gaataaaaaa tatagtttgc ccaaagatta
    11101 ttctcctcag gaaagcagtg aagcgagaga tgctttttat aaaatgaata aagatgctca
    11161 aaagtcagga ttaaatttaa aagcttttag tacatataga agttatgaat atcaagatag
    11221 attatttaag tcatatgtaa aagaacatgg agaaaaagaa gcaaatagat tttcagctaa
    11281 acctggagag agtgagcatc aaactggact tgcttttgat attggaggag atgaccagtc
    11341 ttgttgggca aataaaaagt tcaacaatac aaaagaagct aagtggttgt atgaaaatgc
    11401 atataaatat ggttttatac ttagatatcc agaaggtaaa gagaatataa caggatatat
    11461 gtatgaatct tggcactata gatatgttgg aactgaacat agcaaaaact ttgcaatgaa
    11521 taatttgact ttagaagaat atttacatat aaattaagag atggtttgtt aaaattaggt
    11581 taaaataaaa aataacctag actattagct gtgtaaagtg atataatgta aatacaattt
    11641 agataactac tcgaagggga gtagcttaca cgaaagtggt aattaatcgt caagacagta
    11701 gaaatactcg gttaattagc aagggattcc ttgatagcaa gaccttcaaa ataagcatta
    11761 ggtatgtttg ttttggggtc tttttttatt caaggaattt ttatttaaaa aaatttaaat
    11821 ttcaagtata cataagagcc cccaaacata aaataaattt attgaagagg agggcaacaa
    11881 atgtcttaca aaagtactta tcaagaagta attaaaaatt tagactcaag tttatctggt
    11941 ttgagtaaag aaagagcaga agagttgtta gaaaaaaatg gagctaatga attaaaagaa
    12001 gcagataagg ttcctactta taagcttttc ctagaaagtt ttaaagaccc attagtaata
    12061 attctattga tagctgcttt agtacaaata tttttaggtg aaacagtgga gtctataata
    12121 atttttgcag ttattattat aaactctgtt ctgggtgttg tacaaacaaa aaaagcagaa
    12181 agttcattag aaagtttgaa aaatttatct gcaccaaacg caaaggtaat aagagacaat
    12241 aaaaaaatga caattccagc aaaaaatcta gtagttggag atattgtatt cttagaagct
    12301 ggcgattaca taccagcaga tggaaggctt atagaagcac aatctctcaa ggttgtagaa
    12361 gggatgttaa ctggagaatc agaaccagtt ttaaagcata cagaaaaaat aagtgaagat
    12421 gtaagtttag gtgaccagaa aaatatggta tttagtggtg ctgtagttgt ttatggtaga
    12481 ggttcttttg tagtgactgg aacaggtatg gatactgaaa tgggtaaaat agctgggctt
    12541 ttagaaagtg ctgaaaataa acttacacca ttgcaacaaa aaatagagga ttttagtaaa
    12601 aaacttggtg taggtattgt aatacttgct cttttaatat ttataattca agtagcaaga
    12661 aattacttta tggctggaaa tggagaaatg acacaaatta ttttagattc attcatgttc
    12721 tctgtagcag tagcagtagc agctatacca gaagctctat catcaatagt cactatagta
    12781 ttggctgttg gaacaaatag tatggcaaaa aaacaagcca taataagaaa attaccagca
    12841 gtagaaactt taggttcaac aagtgtaata tgtactgata aaacaggtac tcttacacaa
    12901 aataaaatga cagtagttga ttattatatg tatggaacta ataatgatga gttagataaa
    12961 gaaaaagtaa actattctta tcatgctaaa ttattgacta tggtttctac attgtgtaat
    13021 gactctcata taactagtga tggtaaagaa gttggtgacc caacagaagt agctttaata
    13081 aattattcaa gtaaaaatga tttagattat gataaattaa gaagtaagta tatcagaata
    13141 aatgaaatac catttgactc agacagaaag cttatgtcta ctgtaaatag tatatatgga
    13201 gattatataa tgtttacaaa aggtgctcca gatattgtgt ttagtagatg taaatatgct
    13261 ttgaaaaatg gttcaaaagt agatataaca gatgagataa tagaagaata taaacataaa
    13321 aatgaagagt tttcaaatag agcacttaga gtattagctt ttgcaataaa agatgtccca
    13381 gaagaagatt ttataccttc aattgatgac gaacatgaca tgacattggt tggaataatg
    13441 gcaatgatag acccaccaag agaagaagta atggatgcag taaaagaggc aaagagtgct
    13501 ggtataaaaa ctgttatgat aactggtgac cataaaacaa cagcagcagc aattgcaaaa
    13561 gagattggta taatggaaga aggagacttg gctcttactg gaaaagagct tgatgctttg
    13621 agtgaagaac aactatatga aaaactagaa aatataagtg tatatgccag agtctcgcca
    13681 gaaaataaaa ttcgtatagt aaaagcatgg caacataaga ataatataac agcaatgact
    13741 ggtgatggtg ttaatgatgc acctgcatta aaacaagcag atataggaat cggtatggga
    13801 agtggtactg atgtagcaaa agatgcttct gctatggtat tggttgatga taactttgca
    13861 agtatagtaa atgctgttga agttggtaga acagtataca gtaatataat aaaatcaatt
    13921 acttatctat ttgcaggaaa cttaggagct atagtatcca tagtatttgc agtgtttgca
    13981 ggttggtcaa atccatttac agctttacaa cttttgttta taaacttagt aaatgactct
    14041 ttaccagcaa ttgcattagg gtttgaaaag tcagaaaaaa atataatgaa taaacctcct
    14101 agacacccgg atgaaagtat actagcagga ggaacattga aggcagttgc tataagaggt
    14161 tgtataatag gtgtagttac aataattgca caatatatag gattacaagt atctccagaa
    14221 cttggagtag caatggcatt ttcaacattg atattagcta gaataatgca aacattacct
    14281 gcacgttcta ataatcaaac agtaataaaa ttaggttttt tcagcaataa atacgttata
    14341 ggagcagttt tagtctgtct tgggctttac tctttaacac taataccagt gctaagagga
    14401 atattctcta taccaacaac gtttggattg taccagttgg ggatttgcct agggttagca
    14461 ttaatttcat caatattaat ggaacttaac aaattaataa atagaagtga agtaaaataa
    14521 tcaaaaaatt aaagggcata ttgattttaa caatatgcct tttataaata gtctaattta
    14581 ttctatatta tcgattattt ggaatgcttt tataacttca ggtaattctt tttcttcagg
    14641 cattctaaat cttatgaaat ttttatcaag tccagtaaaa tcacttccag atataactct
    14701 tatttttaat ttagcaaact cttgttgtaa atctatgtcc ttgtttttat gttcaactgt
    14761 cataattgat acagtatcac tagtttcagc tatattaagg tttttccatg gaattaataa
    14821 ttgatttttt atatcttttg ttttttcttt taattcttct ataaattgaa catcatctaa
    14881 taaatttgct gcaatactac gagatatttc agacacttcg taaggagtag aaatcttttt
    14941 aatagggcta acaagttgtt ctggaagaac tgcatatcct gctcttagtc ctgctaaacc
    15001 gaatcctttt gaaaatgttt ttaaagcaat tacattatca taattattta gaagcttgac
    15061 agctgaattt tcttttggca tgtattcacc ataagcttca tctaccataa ctgctatatc
    15121 atatttagct gcttccttta ctatattttc aattgatgat aaatgtataa tttgtcctgt
    15181 aggattgttt ggattgtcta tgtaaattac tttatattct ggatttattt tttcaataaa
    15241 ttctttttca ttaaacttga aattatcctc tttctttaaa agaacataat cataagttgc
    15301 accatgcatt tttatatctg tctcatattc tgagaactga ggtgaatatc ctaaaacttt
    15361 atctcccttt tcaataaata gtctatttaa aaggtaaata acatgtatag aaccatctgc
    15421 caaacaaatt ctgtcagtat ctaatgctat aaaatctttc caataatcga ctatattatc
    15481 ttttaaagca attgaatgag gatatcctct tatcatatca aattttaaag cattaaaagc
    15541 ttctacagct ttgtttgagt aagacacggt atttatacct tcaccacagt ctatctcgaa
    15601 tacatcttct gaatgtccag attctattgc ataacttttt ttcaactgca tttcaatagc
    15661 tttgttaatt tttagtttca tactttatca ctccttattt agtcaataat aaatgttata
    15721 aaagttgcta gatttaaaat attatgaaaa tatataatag taaaaaatga atataaatat
    15781 tataatagct cactttattt aatatgatta tatatcatat attgtaaaat ttctagcatt
    15841 ataagactat aaattgaaaa tattcagaaa aatactacaa gaaacgattt attttgctct
    15901 taaaataagt taaatgaatg ttattaattt tgtaaattga aatagtttaa gtataaagtt
    15961 atgatataat ctaataaggg taattcttta gattatatta aggaaatata ggtatacaat
    16021 aaaaagttat ggagttggat tatgggatat aaattaattg taacagatat ggatggaact
    16081 ttattaggca ataatcataa agttacagat gaaaataaaa ctgcactaca aaaagttata
    16141 aaaagcggta ttaatgtaac tttagcaaca ggaagagcct tcgattcagc taaatgcaat
    16201 gtagattttc ttaaagagga catgccaata atagcttgta atggttcatt aataagagag
    16261 caaaatggaa atataatata ttcaaataag attgatacaa gaacatgttt aaacatttta
    16321 gatgtattag ataaatacga tatttactac caatgtaata gtatagattc tatgctttcg
    16381 aaaaaaatag aaggacgtga agatagatta agtgtatttt taggctctga aacagaagta
    16441 attgtaaaag atgatttgag agaagaaatc tttaaaaaag atatactaaa atttgtaatc
    16501 atagaagaaa aaaatccatc tattttagat gaaataagaa aagaattgag aaaagttcaa
    16561 ggaataaaga taacttcttc atggccaaac aatattgaag tcatgaatga aggtgttgat
    16621 aaaggtaatg cagttaaaat tttagctgaa aaaatgaata tagacagaga agatataatt
    16681 gcatttggag acaattacaa tgacatagaa atgataaagt ttgctggtct tggggtagct
    16741 atgggaaatg cagaagaatt gattaaacaa gaagctgatt atgttacaga tacaaatcaa
    16801 gacagtggag ttgcaaaggc aatttataaa ttcctagagt taaaagaatc acttagctct
    16861 taaaacagta tataatagga aaaaataggt tgactatttt gtagatagta attataatac
    16921 aaatagataa aacataaaaa tttagattca gtgaaaaaga gagtagatat agagaaaatc
    16981 tcagcgaatt gggggatggt gtgagcctaa tgataacact ttatattgaa aagaactttg
    17041 gagaatacta cttgaaattc agtatggtag taggtaatct cgccttaaga gaatagagtg
    17101 ggtaaacatt gtttaccaac tagagtggta acacggaata tttcgtctct tggtcttttt
    17161 gaccaagaga ttttttagtt tcattgagtt acaagactta taattaaaat acaaaaaatt
    17221 aaaatatgag gtgaaagtta tgaaattatg gggcggacgc tttagaaaag cggaaaatca
    17281 acttatggaa gaatttaata aatcttttgg ctatgattgt gtactgtaca aaaaagatat
    17341 cgaaggaagt gtagcacatg ttcatatgca agtaaaatgt ggacttttaa cagaagaaga
    17401 aggaaagtct ataacagaag gtttaaaagg gatacttgaa gatgtagaaa atggaaagtt
    17461 agtattggat ggagagtatg aagatataca tagttttact gagataaatt taattcaaag
    17521 aattggagat gttggcaaga agcttcatac agcacgtagt agaaatgacc aagttgcagt
    17581 tgatatgaga ttgtatgcta aagaaaaagc aaatgatttg gtgggtttaa tatctgaatt
    17641 taaagctact ataaaagatg ttgctgacaa aaacccagtg atgatgccag gctatactca
    17701 tcttcaaaga gctcaagtag tgacatttaa gcatcactta atggcatatt atagtatgtt
    17761 tgatagagat gagaaaagaa taaaaaatgc tatagaaata ttagatgaat cacctttagg
    17821 ctgtggagct ttagcaggaa ctacgcatga tatagataga agtataactt gtgaacaatt
    17881 aggatttaaa aaagtagtag ataattttat ggatggagta agtgatagag attatttact
    17941 agagctaatg agtgattttt caattataat gatgcactta agtagattaa gtgaagagtt
    18001 gatactttgg agttctcaag aatttggatt tgttgagata gatgatttat atacaactgg
    18061 aagtagtata atgcctcaga agaaaaatcc agatggtgca gagcttataa gaggtaagac
    18121 tggcagagta tatggaaact tatttggtct ttttacagta atgaaaggaa taccattagc
    18181 atataataaa gacatgcaag aagataaaga aggttttttc gatagtgtac atactcttga
    18241 aatgtgtata caaataatgg atagaatgat agccacacta aaggtaaatg aggataaaat
    18301 gaaacaagca gtaaaaaatg gttttttaaa tgcaacagaa gttgcggatt atttggttaa
    18361 aaataatgtt gcttttagag atgcacatgg tatagtagga agtatcgtta tatattgtga
    18421 agataataaa aaagcaatag aagatttaac attagaagaa ttacataagt tttcagatgc
    18481 ttttaaggaa gatatttatg attttatcga ctatgagagt atattaaata agggaataaa
    18541 aaagaattta aaataatgta tttattttta aaagctgtaa atttgaatgt tatcatttaa
    18601 atttacagct ttttattgtg taagatttta ttatataaaa gtaagaaact taaaagtagt
    18661 agtatttaaa ataaatacaa ataaaaaatt gttattaaaa tgataattaa tatcaataag
    18721 tattgacaaa attatttcta aatactatta tatataatat aaataataat gaaaatcaat
    18781 atcaaataaa tgggaggaaa tctaatgaac ttattagtga ttggtggtca tgaaagaatg
    18841 gaaaaagatt atatggttat ggccaagaaa aaaggttata agacaaaggt atatactacc
    18901 atgtcatcta aattaaataa ttctatagga agaccagatg cagttgtcat acttacatca
    18961 actgtttcac ataagatgtc tagaacggtt gagtctcaag ctaaaaaaca agatatatta
    19021 atcgtaaggc ataaaaatag tagtaaggta gcatttaatg aatgtctaga tatggttgat
    19081 gaatgtctgg gaaattgttc aaaatgtaag cttaaagaca aacaaaaaca aaaaaatata
    19141 taggtataaa aaatacataa acataaaatt aaaagtactg agataatagt tataattatt
    19201 atctcagtac ttttagattt ataaggataa gtatattata aattttttat tataatttcc
    19261 aactacttgt tactttttca tatttttttt acttctagct ttttttcttt ttttcttctt
    19321 tatatttgaa gctattataa ataaaactaa aagcactaga atacctgcaa taatcttaac
    19381 aaaagtcatt aaaatattat ttccagtaaa aaatggaaga ctgctatcaa gattattttt
    19441 tgcaattaag tctatactgt tttctagttt accattatta tatacattta aagtaccaac
    19501 cttagcccct ttttttatag gcaaatcaat tttatttaac tctgttttgg tatcataatt
    19561 gccttgagat tcatcttttt ctaagaatat cctataacta ttttttggtt cataaatcaa
    19621 ttcatgttgt tttgtaaaca atactttttt agtatctgtg tatttttctt tatcaacaat
    19681 agtagcacac ttaaagttat caaatccata atcaatcaga atacgtgagt ctaaatataa
    19741 atcagcatta gttgaattaa atacagcaac gataactctt ctgccatctt ttacagcact
    19801 cgataaaaga catttaccag cagcatcagt atatccagtt tttataccat caactatatc
    19861 atattttata tttataggtt gacctttgta tgtaatctta tcatgtgatg tcaaaaactt
    19921 attagtgttt acaaagtatc tctcataagg atatgctttt gtagcttcaa atttaagtga
    19981 cttagttttt acaatttgtc taaaagtatc attattcata gcttctctag ctatgagagc
    20041 catatcatga gctgttgtgt agtgatttgg gtctggtaat ccatgaggat tattaaaatg
    20101 agtattagta gctccaattt tttttgcctc agagttcata aggtcaataa atttttgtac
    20161 attgccacca ccaacatatc tagctaatac aaaagcagca tcattagcag aatgaaccaa
    20221 aagagcatct agtaactgct ttacagtaaa agattcccca ttttttagat acatactaga
    20281 gccatctatt tgaggtaaat ctttaatttc tattacttga tttaaatctt taacctcctt
    20341 tagaactaaa caagctgtcc atactttagt tgttgaagct ggataaagct tagaatttcc
    20401 atccttatta tatagtattt tgccagactc atagtccatt aaaactgcat gtttagcaac
    20461 tatagctggt tcattatctg caaaagagat attagagctt cctaaaaatg aagtaaatat
    20521 caataaacag attaataaaa gtgataaatt tcttttcatt gtgagcctcc aaattttaaa
    20581 ttcatctttt agtatagcat atatttgtca ataattaaaa gaaaggagtg attaatatat
    20641 gaaaaaaaaa gtaaaattta tttcgttttt tgttttattt attttaataa tatcatcaat
    20701 aatcgtttat aaatcgctta ttttcaaaga tgatatttat gttgtaagta aaaaaaattt
    20761 acctaatgaa aaaacacatg ttgtagagaa tgaaattaaa ggtgaagata ataatcacaa
    20821 taaagtaact aaagacatag ataaaaattt tcaaaataat aaaataacta tatacataag
    20881 tggagcagta aatagacctg gaattgtaac tatagagtca gacaagagac tttatgatgc
    20941 tgtagaatta ctaggaggaa cgacaaaaga agcagattta aatggagtca atctatcagt
    21001 aagattagaa gatgaacaac attacataat acccaaaata ggtgaagcaa catctgttac
    21061 aagtaatgat gattccaata aaccaaatca gaggaatgag tcaagaggtg agcctaaaaa
    21121 taaatccaat aaaaatatat ctaacgaatc aaaagtaaat ataaatgtag cgactataga
    21181 agagttggat tctctacctg gggttggaga agctacagcc aataaaattt tacaacacag
    21241 agaagaaaat ggacagttca gttcaattga ggaaataaaa aatgtaaatg gtattggaga
    21301 taaaaagtat gaaaatataa aagatttaat ttgtgtagac taaaatataa tacaaaactt
    21361 acatatagat atgttattat aaatatgtat gtatatgtgt gtacatgtgg aaatttagta
    21421 aaggaggcac ttttatgaaa aaagaacaaa aaaaacttac agagatgaca acagcaggtg
    21481 gttgagccgc taaaataggg ccagaggttc tggcatcagt tttatctcaa ttgcctaaaa
    21541 atgataatat agaaaattta ttagtaggac tagatacagc agatgatgct gcagtttata
    21601 aattaaatga tgatatggca cttatccaaa ctttagactt ctttacacca atggtagatg
    21661 acccatacgt atttggtcaa attgctgcat caaattcact atcagatgta tatgctatgg
    21721 gaggcaaacc tttggttgct atgaatattg tttgttttcc atcatgccat gatatggatg
    21781 tacttgcaga aatattaaaa ggtgggtttg ataaagtgaa agaaagtgga gcacttttgg
    21841 ttggagggca tactgtagat gacaaagagc ctaaatatgg tctttcagtt tctgggattg
    21901 taagtccaaa taaagtttta tcaaatgcta ctgcaaaacc tggtgataag ttaattataa
    21961 caaaaccaat tggagtgggt gtattaaata cagccatgaa agaaggtatg gtagaacaac
    22021 atatagcaga taaagtaata gaaataatga tacatttaaa taaatatgca gcaatgagtt
    22081 ttgagaaatt tgatgtaaat tcggttacag atataactgg ttttggtcta cttggtcata
    22141 ctttagaaat ggccaaagct tctgaagtaa gtattgaaat tgaatcaaaa catgtaccaa
    22201 ttattgaagg tgcaatagaa atggcacaaa tgggaattat acctgctggt atgtataaaa
    22261 atatgcatta tgtatctaaa gatgtagaag ttgtaggaaa tatagaagtt gcagttcaag
    22321 atattttata cgacccacaa acatcaggag ggttgttaat ttcagtaaaa gaagaacttg
    22381 cagaggaact tgtaaaagat atgaaattaa atggagcaat agaagctaaa attataggtt
    22441 ctgtagttcc aaaaggggaa aaatatatta cagttttata aaatattata gagaaagagt
    22501 gattgttttg agcaaaagag aattgtttgc aatgttgcct tcagttgatg aagtattaag
    22561 tgataataga attgtagaaa taataaatga atatcctaga agtttagttt tagaatctgt
    22621 gagagaagta atagatttaa aaagacaatt tatattaaga ttaaaagaag atgcatcaaa
    22681 ctctgtaaca atagagtttg gtgaaataat agaatctgca atagagagag ttaagttaaa
    22741 ttactcatta tctttaaaaa aagttataaa tgcaactggt acagttattc atacaaattt
    22801 aggaaggtct ttacttagtg aagatataaa agatgaatta tggtgtgctg cttcaaggta
    22861 ttcaaactta gaatacgatt tggataatgg agaaagaggt tcaagatact ctcatttaac
    22921 tagtacaata aaaagactta ctggagcaga agatgtacta gttgtaaata ataatgcagc
    22981 ggcagtactt cttgtactta gcacaatggc taaaggagga gaagcaattg tatctcgtgg
    23041 agaattagtt gaagtaggtg gttcatttag gattccaagt ataatggctc ttagtggtgc
    23101 agaattagtt gaagttggtt caactaataa aactcatttg aaagattaca aggaggccat
    23161 tacagaagat acaaatgtat tgatgaaggt tcatacaagt aattatagaa taatgggatt
    23221 cacagagagt gtttctatag aagaattggt taatttaggt aaaaaatata aactacctgt
    23281 aatagaagac ttaggaagtg gagtttttat agatttatca aaatatggtt tatcttatga
    23341 accaactgta ttggattcta ttcgacaagg tgcagatgta gtaactttta gtggagataa
    23401 gatgcttgga ggtccgcaag caggtattat agttgggaaa aaagagtata tagaaaaaat
    23461 gaagaaaaat caacttacta gagcacttag agttgataag cttacaatat gtgctcttga
    23521 agcaacattg agaatgtatt tagatgagac aaaagctata gaaaatatac ctactttaaa
    23581 aatgttgaca tataaaattg aagaattaga agtaaaagca aataaactat ttgaaaaaat
    23641 aactgcttta aacttaaatg caaacataaa tatagaagat ggattttcac aggtgggagg
    23701 agggtctatg cctcttgaaa ctataagtac aaaggtaata tcaataactc ctgaacatat
    23761 gaatgtttca tctttagaaa aaaaactaag acttagtgaa gcacatataa tagccagagt
    23821 gtatgataat aaatatgtac tagatgtaag aactatattt gatgatgaat ttgatgtaat
    23881 agttgaggaa ttgagaaaag catttaatta aataaatttg agttaataaa tattaaattt
    23941 agaagtataa gtatgaagtt ttgattaaaa aatagctaca cacacttgtg actttagtca
    24001 tagcaggttt agagggggca aaaaatgaaa aatgtagtaa ttggaacagc aggtcatatt
    24061 gaccacggaa aaactactct tataaaagca ttgactggaa gagagactga tacgttagat
    24121 gaagaaaaaa agagaggtat ttcaataaac ttaggattta cttattttga tttaccaaac
    24181 aatagaagag ctggaattgt tgatgtccca ggacacgaaa aatttataaa aaacatgtta
    24241 gctggagcat caggaattga tatagtttta cttgttgtag cagcagatga aggggttatg
    24301 ccacagacag ttgagcattt agatattcta agctttttaa atatcaaaaa tggaatagtg
    24361 gttctaacta agtctgatac tgtagatgat gaatttagag agctagtaaa agaagatatt
    24421 tgtgaaaaaa taaaaggaac ttttcttgaa gatgctgaaa taattgaagt tgattctata
    24481 tctaaaagag gtatagacac tcttattgaa aaaatagata aaatgagtga tgatatagaa
    24541 gataaaaatg aaaactctcc agcaagactt aatatagaca gagtattttc aataaaaggg
    24601 tttggtactg taataacagg cactttaata gaaggaaaga taagtataga agatgatttg
    24661 gttatatatc cacaggtatt aaaaacaaaa ataagaagta tacaagttca tggagaaaat
    24721 aaagatacag cttatgcagg tcaaagaaca gcaatcaata tatcaaatgt aaaagtggat
    24781 gatataaaaa gaggagatgt tttagctgca ccaaactcat tggaggaatc aatgatgtta
    24841 gatgtaaaat tatcattggt aaatcattta gataaaggat taaagcactg ggatagatta
    24901 agattgtatc atggaactag agagatactt tgtagagcag ttccactaga taaagaatta
    24961 attgaaagtg gagaaagtgg ctatgttcag ttgagacttg aagaaagcat agtatctaag
    25021 aaaggtgata cgtttgtagt gagacgttat tctccaatgg aaactatagg tggaggtgta
    25081 ataattgacc catctcctaa aaaacataag aaatttgatg aaaaagttat agaagcatta
    25141 aaaataaaag aaaaaggcga actaaaagat ataatagaag agtacttaaa aaggaattta
    25201 aaaaattatc caaatataaa agaaataatg agctatagtg gtgctcatga agaagatgta
    25261 aaaagagcgc ttgaaacact tatatcagaa gataaagtat ttattatagg aaatatgtat
    25321 atgcatataa atcaatacaa taaattaaaa gaaaatacaa taaagctttt aagtgagtac
    25381 cataagaagt ataggcttag aaaagggata ctaaaagaag aagtaaggtc taagatagag
    25441 agtaatttta agactaggga gatggatatt ttattagaaa aattgtctac agaaaatgct
    25501 ataaaaatag aaaataatat agtatctcta ttagattttg aggttatttt aaatgataag
    25561 caaaaagaaa tagcaaaaaa aatagaaaaa agattaaaat catgtggagt ttcttctata
    25621 ctgacaatag atgaagtttc tgaaggaaat cataactatg ctgaagtatt ggagtcaatg
    25681 ataggtaata aagtagagaa attagatgat ttgtatataa tggacaaaga tatttatgaa
    25741 aatgcaaaga acattttgat aaattatata aaagaaaata aagaaataac attaggagaa
    25801 tacagagatt tgattgattc tagcagaaag aattgcatga ttatattgga aaacttcgat
    25861 agaaacaaaa taactaaaag agtagaaaac aaaagaattt tgttttagca gaaaatgtct
    25921 gtttttgctt taaggtataa agaaggaatt ataatgtcga gtatcgtata attaattagt
    25981 ataaaatatt aattaagagg aagtgtaaag tattgaagaa tataatacct gatgtaaaac
    26041 cagatataaa agaaagagaa gacatgagcc ttttatttat aataatgggc tcagtacttt
    26101 tattatttat tataaaagat atagagaaat atgaaacttt attacatgcc atatatacga
    26161 tatttttagt agctacagga gtaattatat ttaatactac aaaatttaaa gtagattcat
    26221 tttctacatt tttaggatta atttttatag ctactggagt attggagtgt atatatttat
    26281 ttaattcctt ggggattaaa actaagtcta taatggagat taacatcaca atatcagcaa
    26341 taacagattt atttcctata ctgggtgtat acttaagttt taaatttgtt aaggataaca
    26401 aacaaattta ttcaagtgta attttattta tagcaactgc tacattaaca ataacatctt
    26461 tattcataat atcaggaatt tgtgactatc tgggaaatgg taaatcacaa tatgctttag
    26521 gagttataat atctatattc ataataatta tttctatcat tagtggaatt gaattaaatt
    26581 caagttcaaa taaaggtaaa tgggaatatg atgaaaaaaa gatttttaac agaataatag
    26641 taataataat cttatcaaga gttccaaatc tattgcatat agttattgat aatagaaatg
    26701 tagagaggat attatcacaa ataataataa atgtagcctt atattattta tataattaca
    26761 tagtatctaa gaatattaag aaaacagcac tggaattgca tgatacgaat gaagaattaa
    26821 caaaaaaaac ggaaagttta aaagaaaaga ataaaaaatt aatctatgag acagaaaaga
    26881 tagaggaact taagggaata cttatgaaaa gagaatctag gctacaatct acattagatg
    26941 tagcagtaaa tagcatagta gtatttagca aagatggaga aattacatat gcaaataaga
    27001 gctttagaaa tacttttgga gactataaag aacaagataa attgactgat aaaataaaaa
    27061 acttcaatga tttgatagaa agcattcatt atgtgtttgt tcatgagaag aatgcagaga
    27121 aacttattag tacaagcgat aataaagttt atcaagctat atttgcacct ttaattattg
    27181 cttcacaaac agaaggagta ttgtgtgtac tagaagataa gactaagaaa aaggagtacg
    27241 aacgcaaact tattgaagca aataagagaa gtaaagattt tttagaaagt attggagatg
    27301 gcatagtagt gcttgaaggt aataacaaaa tatatgttaa taatgcatgt agggaaattt
    27361 ttaaaaataa tttagagagt attgattttt cattagtatg taaaagtgaa gaaagtatag
    27421 aaaaaagata tgtaatagat ggtgaagtaa agtatgtaga gatgagtttt tctcagtata
    27481 ctaatgctgg tactaataaa actattattg taatacgtga tacaacctct cgaaaaatat
    27541 ctcaaataaa acttgaggaa agtcaatcat catattcaag atttatagat atattacctg
    27601 atggcatatg cttattaaaa gaagatttaa gtataaacta tgcaaataag tcgtttttag
    27661 atatgctagc ttttacaaac atagatgata taaaagattc taatattaaa ctattaatga
    27721 atgcgaatac tgaagaaaaa atgaaattta cggataatat ggctaaagtt ttaaatgaaa
    27781 atagaagtat acttttactg gaatatgaat tgataaatag ttatgatgat atagtagaag
    27841 tagaattaag tgcattacct tttgctatat acaatactag atacataatg cttattataa
    27901 aagatttagt acataagaaa tattccgagc aagcagaaaa agaactgctt gaaagattta
    27961 aaacagataa aatcaaaacg gagttttttg caaatatgtc tcatgaacta aaaactccac
    28021 taaatgttat atctagttca aatcaactgg tagattcttt ctatagaaat gaaaagataa
    28081 aagattacaa taacaatatt aaatctcatg tggatttagt tagacaaagt tcttataggc
    28141 ttcaaagatt aataaataac attatagatt taacaaagat ggagtctggg ttctatacac
    28201 taaaacttgc gaaatacaat attgtatctg taatagaaga cttatttatg aatatagaag
    28261 agtatgcact tagaaaagac ataaaaattc tttttgatac agaccttgaa gaaattaatg
    28321 tttatataga caaggttgaa attgagagaa ttatgttgaa tctattgtca aactgtatta
    28381 agtttactga taatggaggc tggatatatg taagtattca ttataaaata gataaagtaa
    28441 tcataagtgt aaaagacact ggagttggaa taccacaaga taaattagag ttgatttttg
    28501 aagaattttc acaagttgat aagactttat ccagaaatac tgaaggaagt ggaatagggc
    28561 ttgctatagt taagaatcta gtaagtcttc atggtggaga tatagaagta gtaagtgaag
    28621 tgaataaagg cacagagttc ttaatttcac ttccaatgaa gggatttagt agtgaacatt
    28681 acacagaaga taagagaata tataatattc aagaaaaaat aaaaatagaa ttttctgata
    28741 tatattatta aaaatgatta tgagcaaaaa taaaataaaa atactatttg tttaaatatt
    28801 taagttgtaa gaaataggct atcataaggt aaattattat gatagcctat ttttagctag
    28861 gttttatatc tatatgtgag aacatataat ctctaaatta ccttcaaaac taaaatctcc
    28921 aaagtcgttt ggtagtataa aatgcatacc cttttttaaa ttgtattcta cagaattgtg
    28981 tataagtttt ccatttccat ccaacacact gtataaagaa aaaggtgtat tgtgtgtaaa
    29041 attacatttt ccaaaaacat ctaatttata aacactaaaa aattcgtttg acacaaatgt
    29101 tgtgcattta aagtctgatg ttgatacgat tttatagtca gtatcgaaat ttatatgagg
    29161 aacattcgta acatctattg atttttgaac atgaagttca cgcttattac ctgaattgtc
    29221 agttctatca taatcataga ctctataagt agtatctgag ttttgttgag tttctaaaat
    29281 caatgttcct ttgcatatag catgtatagt gccacttgga acatagaaaa agtctccctt
    29341 ttttatatta acctttctaa gtagtttgtc ccattcatta ttatttacca tatttacaaa
    29401 ttctttatga gattttgcat tatgacctat tataatttct gcatcatcag aacaatctat
    29461 tacataccaa cactctgtct tacctaactc tccattttca ttttttttag catattcatc
    29521 atttggatga acttgaactg ataaattatc atttgcatcc aatatttttg taagtaaagg
    29581 aaacttatca ccaggtgtgt ttccaaataa ttctctattt ttattccaca attcagatag
    29641 ttttttacct ttatattttc cattttctat taagcaatct ccatttttat gagagcttat
    29701 agcccaacat tcaccagttg ttggcgaatc tatttcataa ttaaatttat ctttaagtgc
    29761 agtaccaccc catattctat ccataaaaat aggttttaaa aataatggtt ccataatcct
    29821 gttcctccta tgatattaaa tttatcctac aaataattat atataaatag attataaaat
    29881 caatagtaaa aaagttttgt cccttgaaat gacataaagt ataaggagtt attaaataag
    29941 ataaactatg atatataata taaagttcta aattggagtg ataattatgg agttgtttaa
    30001 ggcagaaagc aaaaaatata aaaaagaatt tttaaaatta ttggagcaat gggttagtat
    30061 accttcattt tatgatagaa aaactgtatc taaagacatg ccttttggaa aaggagtata
    30121 tgatgcatta aactggtttg aaaatctagg tagagaaaac aatttcaaag taaaaaatat
    30181 agataatcat gctgttcaaa ttgaatatgg aaatggtaaa gagtatgtag atatatttgg
    30241 acattgtgat gttgtaaatc caggtgaagg atgggatagt gaaccattta aactaaatat
    30301 tataggtgat aaattagttg ctagaggtgt atctgataat aaagggccta tgatagtgaa
    30361 ttttttagca ctaaaaatga taaaggattt agatattaat ttaaaaagaa aggttagatt
    30421 aatagctggg ggaaatgaag agagtggatt taaatgtata aagcattatt atagcaaaga
    30481 gccatatggt gtatgtggat ttactccaga tgctaaattt cctgtattaa atggagaaaa
    30541 aggtggagca ataataaagt taatttcaaa tatagacgat aaatctttat atataagtgg
    30601 tggaatagag tttaatacaa taccagataa agtttatata aagaatgtag aaaaattggg
    30661 taaagataat atatgttttg atattaacaa tatatcgata aattatgata atggcaatta
    30721 tattgtgtat ggaaaaggtg gtcattcatc taaacccgaa aaatcaataa atcctatatt
    30781 agctacaatt aaacttttgt cagaaaatat tgatgaaaaa tggacaaaag atttatataa
    30841 gttgataaat caagataata taaatggaaa cttatttggt ttaaatattg aggggaaatg
    30901 tggaatttta tcaatggtgc caacaataat aaatatagta gatggaaaat tagaagtagt
    30961 tttaagcgtt agatatccag aaatattaac cattgaagat ataataaaaa aatttaattt
    31021 gtatatggag caaaataata ttaataaatt tgagcttatt ggggaaaatt taaagcaagc
    31081 aaattatata gatagaaatt caaaacttgt aagaagtttg catgatatat atataaagta
    31141 ttctggagat ttaaaaaatg atgttagagt aactagtgca ggaagttatg cttctgaaat
    31201 gaataattca gtaatatttg gttgtgaatt tcctgatggt agctttggca atgtccatag
    31261 tgcgaatgaa tttgctagct tagatagatt tataactgca ataggtatat atgcagaggc
    31321 aataattaca ttatgtaata aaatataaat acaaaatgtc ccttatatag acatattata
    31381 tatacaatta aaattttact tgatatataa ttgaaatcaa agagaaggtg atacaatgat
    31441 aactaagaaa catgcaataa tagtaaagag tttaagcaat aaagatggat atatgacatc
    31501 aaacgaatta gctatcaaat tggatgtgtc tactaaaact attaaaagat atatagcaga
    31561 tttaaatagt gttttaagca aatatgattt ggtaatagct tcttctagag gtataggata
    31621 caagttaagc ggttctaaaa acaatatagc cagagctgtt aaagaagcaa ataaatatat
    31681 tgatggtttt ttagatgact ctgaagagtc aagaatgtca aatataatat gtatgcttat
    31741 taatagaaat tatatgagta tagaagcaat ggcagaagaa ttaaatctaa gtatagccgc
    31801 tataaataaa ttgtctagta agcttaaaag aaaacttgaa aagtatgact tagttataaa
    31861 atctaaacct tactatggaa gctatataca tggtgaagaa attaatataa ggcaattaat
    31921 tactgactat gcaataaaat tagatgaaaa aagtaaagtg aaggtgtttt tagatgacat
    31981 tagtgaaaac gatatacact gtatagaaag tattttagaa aagcacttaa gagaaaaaga
    32041 tacaataatt tcagataaag attttaatct tttgctttca aaaataatcg tttctgtatt
    32101 taggagtaag agaggtcata gtaacaatat aaacttaatg gatacaagtt atagatttca
    32161 taactactac tttatagaaa atctaatgaa agaaatatct gataaaattg gatttaaact
    32221 tattgaagat gaagtaattt atatttcaaa ttattctggt gtaatagcct ataaaggtac
    32281 acaaggaaga aaaaacacaa gtgaaattga ggaacgaata agtactgtta taagtagtgc
    32341 acttcaagat atattcctta tttcaggtag tgattataca aaagatgatg agtttatggt
    32401 tgcaatctct gaccatataa agagattttt aaatagagct agagctaatg taaaatcaaa
    32461 taatccttta cttcatcaaa taaaagagaa gtttcctata gcttttaatt tagccgtgtt
    32521 tttatcaaat aaactagaaa ctgagtttaa tttaaaactt gatgaagatg agcttggata
    32581 tatagctatc cactttgctg cttcaaatga aagaatgaaa aaaaatacta gtaagaaaat
    32641 ttgtatagtt tgtcattatg ggataggaac aggacaactt atttctgaaa agctaaaaca
    32701 gaatataagt gatttaagtg ttgtgggtgt ttatccagtt agatatctcg atatggctat
    32761 aagtcaagat gttgatttga tagtatctac agttgaatta aaaggatatg aaaaacctgt
    32821 cttatatata gaaaatatat ttgatgatag cttaattgaa aacgtaaaca aagcctttta
    32881 tgaaaaggaa gaaagaagaa agataataag taacatgttt gatgaaaaag cttttttcag
    32941 tataaaggct agtactaaag aagaggtcat aatttcactt tcaaataaac taaaagaaag
    33001 agattttata gaggaaagtt ctataaaaag tataatagat agagaaaata tttcatcaac
    33061 tgaaatagga aatctagtag caatacccca cacaatagtg aagggagata aaaaatctat
    33121 aataggagtt ggaatacttg aaaatccaat aatttgggat aagcaagagg ttcagctagt
    33181 atttatggta ttttttaata ctaaagaaaa acataatttc tcgatattta aataccttta
    33241 taattttata aaagatgaag gaggagtaag aggaattatt aaaatatgtg actttaataa
    33301 attaatggca cttataggta attaaggagg aaattaataa tgggaacaaa catatttaac
    33361 aaagaatatg tatttttaaa tgttgatgct aagtcaaagg ttgaagtttt aaaatttata
    33421 tcaaaaaaag ctaaagactt aaacttggca gaagatgaga gcttagtata tgaaggttta
    33481 atggctagag aagaacaatt tactacaaat ttaggagaat ctatagcaat acctcacact
    33541 aaaaatgatg caattgaaaa tccagcagta gtagtattga agtttaatga agatgttgtt
    33601 tggaatgaag gtgaggataa ggttaaatta gcaataagct tacttatgcc aggaaaaagt
    33661 aaagagaata ttcatcttaa attattatca tctctttcaa gaaaattaat aaataaagaa
    33721 tttaaagatt ctcttttaaa aagtgataat gttgaagaaa tatctaactt aataaatgaa
    33781 gctttaggtt tataattaaa cactaaggtt ataaaataaa aaaataatta actaaaaata
    33841 ggaggaattt gaaatgaata aaaaattagt agcattatgt gcttgtccaa tgggactagc
    33901 tcacactttc atggcagcag aagcaataga gcaagcagca aaggcattag gttatgaagc
    33961 aaaagttgaa actcaaggtg ctgatggtgt acaaaatgag ttaacaagag atgatatatt
    34021 aggagcaact atgataatac atgcagtagc aataacacca gaaggtatgg aaagatttga
    34081 tggttgtgaa gtttatgaag ttgaattaca agaagctata aaaaatgcag aaggtgttat
    34141 aaaagaaata gaagaagatt taggaatata ataaatttat tgtggaggaa atagaatggc
    34201 aattaagaaa aaagttataa acagttcagg tgcttctaca acaggaggaa ataatgtagg
    34261 aaaatctact ccatctagtc caactcaatc aaagggaaat ggaaaatgga aagaaataag
    34321 taaacatata atgacaggta tatcatatat gataccagtt ttagtaatgg gtggacttat
    34381 aggggcctta tctcaattaa taccatatgc tatattagga cttgacccat ctgtaggtat
    34441 agttgatgct atgaactcag gagaatttac agggttcaag cttagtcttt taaatatagc
    34501 acaattaatg tcaaatttcg gatttacttt gtttggattt gcgataccac tgtttgcagc
    34561 attttgtgca aactctatag gtggaaaaac agctttaatt gcaggattta taggtggata
    34621 tatagctaat aaacctgtag gtgtaccaca attcgttgat ggacaatgga ctgaagttgt
    34681 tccagttgca tcaggatttt taggtgcaat actaatagca tttataatag gatattttgt
    34741 aaaatggtta aataaatcta taaaagtttc tcataactgg ttagctttta aaacaacatt
    34801 tttaatacca ttaatagcgt cattagcttg tatggtattg atgatattta taataactcc
    34861 atttggtgga ttaattaatg aaagtatgaa aaacttctta acagcagcag gagcagctgg
    34921 agaatatgta tatgcaacag ctttggcagc agctacagca ttcgacttag gaggaccaat
    34981 aaataaagca gcaggattcg ttgcacttgg tttaactaca gagaatgtac ttccaataac
    35041 agcaagaaca atagctatag ttgttcctcc aattggatta ggattaacaa cattattaga
    35101 taaaagatta gtaggaagaa gagtatatga tagacaattc tatcaagcag gaaaaacttc
    35161 tatattctta tcatttatgg gtatatctga aggagcaata ccatttgcac ttgagagacc
    35221 aggttttgtt atacctttaa acatagttgg aagtgtaata ggagctatta caggtataat
    35281 tctaggagca attcaatggt tcccagagtc agctatatgg gcatggcctc tagtagataa
    35341 cttatttgga tatataatag gtatagcagt tggtgctata ttcatagcag taggaaatat
    35401 attctataga aataaattaa taaaagatgg taaacttgtt gtagattata tcgactagta
    35461 tttaattttt actatctata aataactttg gctggtaata tggttttaat caatattacc
    35521 agccttacct atatgattaa ttaaaggcgg tggagataag atatggataa gatagaaaaa
    35581 gtaagagagt attttagaga atatgatata gatggatttc ttataaatag tcctacaaac
    35641 aagttttatg ttggaaattt atttagctct tcaggttatg tttttataac taaagaatca
    35701 caatatataa tagtagattt tagatatttt gaagaaatta aaagaaaatc tagtttgttt
    35761 aatgtagtat taatggacaa aactagaact cattttgata taattaatga tatttgtaga
    35821 gagcagaata taaaggaaat tggatttgag ggaaatgaag tatcttttga tttatataga
    35881 agtatgagta ataagttaag tgcaacctta aaatcagttg atttatctac attaagggaa
    35941 acaaaaaatg aagacgaaat aaaatatata aaaaaagctt gtgaaatagt tgatgctaca
    36001 ttttatcata tagtagactt tataaaggtt ggtatgactg aaaagcaagt tgaaaatgaa
    36061 attgttagaa ttataaaaga tttaggtggt caaaaagaat ctttcgatac aatagttgca
    36121 tctgggctta gaggagcatt acctcatgga aaagcaagtg aaaaagttat agagtatgga
    36181 gattttgtta cctttgactt tggtgctaag tataataatt attgttcaga tattaccaga
    36241 accatttgta tgggtactat aaataaagag ttagaagaaa tatataatat agtaagaaaa
    36301 gctaatgaag agtgtataag ggttttaaga ccgggaatga ctactggaga gatagataaa
    36361 gttgcaagag acataattgg ttcatatgga tatgccaata attttggtca taatctgggt
    36421 catggtgtag gaattatggt tcatgaatat cctgcattag ctcctgaatc aaatgaagta
    36481 ttaaaagaag gaatgattgt aactatagag cctggtatat atgttccaag tcttggaggc
    36541 gtaagaatag aagatgatgt acttataaca caagatggat gtatgagatt gactacatct
    36601 actaaggatt taatagttgt aagctaaaaa taaattagat aaatatttta taacaataag
    36661 aaaagaagag gtaaatttaa atgtataatt ttgatgataa accagataga gtaagtgaaa
    36721 agtgtagaaa atgggattta aatattataa gagataaatt tggagatatt agagaagatt
    36781 ttataccaat gtggattgct gatatggatt ttaaaatacc aacagaaata gaaaacaaat
    36841 ttattgaagc tgtaagaaga ggtgtatttg gatatacata ctgttatgat gaattttatg
    36901 attcagttat tggttggcaa aaaaatatgc atgaggtaaa tgtagaaaaa gaatggatta
    36961 cattaactta tggaactgta tcaacacttc attatgtagt acaagctttt tgtaagaaag
    37021 gtgatagtat aatattaaat acaccagttt atgacccctt tgaatcatca gcaaaaaaac
    37081 aaggtgtaaa tgtaatttgt aatacattag atgttgtaaa tgatagatat tatataaatt
    37141 ttgataaatt agaagttcaa attaaagaaa ataagcctaa attaatgatg ttttgtacac
    37201 cacataatcc atctggaagg atatggacaa ttgaagaaat gacaagggta gcaactatat
    37261 gtaaagaaaa taatgttatt ttggttgcag atgaagtaca tgcagagcat attcattatg
    37321 gtacatttaa ttcaatactt aagattggaa aagagctttt agaaaatgtt attctattga
    37381 catcaccaaa taaaggattt aatcttggtg gattaaagac ttcttattca atagttataa
    37441 ataaggatat aagggacaaa tttagaaata aattaaagca aaattctata acttctccaa
    37501 atgtgtttgg aataatagga ttgataaccg cttataatga atgtcatgag tggttaagtg
    37561 gtgtaaatga atatataaaa tcaaattatg aacttttaga aacttgggta aataaatata
    37621 ataagataaa attgatgaaa atggaatcat cttacttagc ttggatggat ataagtggat
    37681 taggtattag tgcaagtgag tttacagata aattggctat agatacagga gtattattag
    37741 aagatggaag tcattttgta aaagatggtg agaagtatgt tagaataaat ttaggaactc
    37801 aaaaggaaaa tgtaattgaa gccttaaata gaatggattt atttttaaag tctttataaa
    37861 aatttggttg aattagtatt ttatataaat ttaaactatt aatatggtat atacataagt
    37921 agaatttgtt ttagattact taagtatata ccatatttta tataaaaatt aaatttgcat
    37981 tagtcatgtg ataactattt aaattcatat gtattttgta tgtataatag atataattat
    38041 tatttaaact tattgtttat ttaatttttc aatagaaaaa gatttatctg taagtttaaa
    38101 attatctttt atacccttag ttaagtatac tttcttatcc ttagttatga atatagcatc
    38161 tacattatca attttattaa ttaaattcat acctttttca agaccaagac caaatgtaga
    38221 agtggataag gcatcacaat taatagattt atcagagatt attgtaacac tacttaaatt
    38281 gttttcaaaa ggataccctg taaatggatt taacatatga tgatatattt ttccgtcttt
    38341 ttcgataaat ctttcataaa ttccagaagt aacaacagac ttatttgtag tttctatgtt
    38401 tcctatggat tcaccatttt tactagttgg gtcttgaata cctattttaa aaggtttatc
    38461 atttttacca ttttctaaag taaatatatt tcctcctaag tttactaaac ctttttttac
    38521 atcctctgat tttaaatagg ctacaatttt atcagcagca tatcctttag ctatggcacc
    38581 taaatcaatt ttcatatttt ctttggttaa ttttatagat ttattttttt catccaatat
    38641 gatgttctta taatcaataa gaggcagaag tttttgtatc ttagaatcac ttggaacttt
    38701 agctttatct gttccaatag cccataaatt tgataatgga ccaattgtta tgtcaaaata
    38761 tccatctgat aatttggaat attgtatagc ttcttttacg acgaaaaatg tatcatcaga
    38821 aactctgaca aattttttac cagcattatc atttatttta gaaacatcac ttcctggtat
    38881 atgagtgctc attttgttgt caatatatct taaaattgaa tcacattcat ttaagatttt
    38941 atcacttttg gattctttta cattaaatac agtaacttcg tttactgtac caaggtagta
    39001 gctagtttta ctatatttag tattctggct tgaactccta aaaaatgaaa ataaaattaa
    39061 tgctaaaatc aatatcacaa aaataaatgt gatttttttc ttattcatgg tatattcctc
    39121 ctatgaaatt gtgttattat tttattataa cataatttca taggaggaca aaaaatgaag
    39181 aaaaaagaca ttcttcttat tttaggcatt ttggttgtta ttacagcatg ttatgggata
    39241 ataaatgtta taaattctaa aaatgctgga aatattgaga tttatgtaga taataaattg
    39301 tataaaactg tttcaataaa tgccaaagaa gaatttaaaa tagagagtag aggggggtat
    39361 aacatagtaa agattcatga taaaggggtt gagatagtag atgcttcatg ccctgataag
    39421 gtttgcgtac atactggatt tataaacaag ccaagtcaaa gcatagtttg tatacctaat
    39481 agagtgagca taaaaataaa tacaaatgaa aagaatgata atcaagaaga tataatttct
    39541 aaataaaata ataaaaataa ttgaaaggaa ttggtgataa ttatggttaa cttaggaaac
    39601 gattgggatg aattattgaa agaagaattt gaaaaagatt actacttaaa cttaagaaaa
    39661 tttcttatag aagaatataa aacacgccaa attttcccaa atatgcacaa tatatatgaa
    39721 gctttaaaac acacttcata caaagacaca aaagtcttaa tattaggaca agacccttat
    39781 catggagata atcaagctca tggtttagct ttttcagttc aaccacaagt gaaaactcca
    39841 ccatctttat taaatatgta taaagaatta aaagatgatt taggttgttt tatacctaat
    39901 aatggatatt taatgccttg ggcagaccaa ggagtgttac ttttaaatac tgctcttact
    39961 gttagagcgc atgaagctaa ttctcataag aacaaaggat gggaaatttt cactgataga
    40021 gtaatatcta ttttaagtga gcgtgaagac ccagttattt ttgtactatg gggaagtaat
    40081 gcacgtaaaa aagtagagtt gattgataca agtaaacatt atattttgga agcacctcat
    40141 ccaagcccat tgtcagcaag taaaggcttt tttggatgta aacacttctc taagataaat
    40201 gaaattttga aaaagctagg aaaagaacct attaattggc agatagaaaa tatataaaag
    40261 taaaaggtaa caaaatgata acaaaacaac aataaacaat gacattgttg taactaatag
    40321 aaatatgctt aaatagttga aaatactatg tatgcatatt tctatttttt tgtcaagttg
    40381 acaactcttg aaaaaatagt tacaatttag ttacacaaaa aacacaaata aaaaaagaaa
    40441 cttacaaagc agaattttat gaagcaaaat atatagtgta aaaaatctta gggaggaaat
    40501 tttatatgaa ttttaaaaaa ttgagtaatg ctaaagtctc ggtaatggca gttgttttat
    40561 cagttggaat attatcggga tactctgcgc ttaataaaca agtaacatta gtagtaaggg
    40621 gagaagaaag aactatatca acatttagtt ctaatgtagg agacctttta gaatctcaaa
    40681 acattagcta tgattcaaat gatatagtaa ctttagatga aaatacaaag ttatctaatg
    40741 gagataaaat agaagtaatt gatgtaaagg aaaaaacagt tgtagaaact aaagacattc
    40801 catttgaagt tacagttgtt gaagatggct ctttattaaa gggtgattct aaggttaaag
    40861 aagaaggaaa gtctggtaaa agtgaattaa tatataaaga aacttatcac aatggaaaga
    40921 aagtagaaaa ggaatttgtg aaaaaggttg ttaaagctga gccagtaaat aaggttgtaa
    40981 gcaaagggac aaaggtagaa atgcaagtag cctcatcaag gggagaaagt tcaagaagaa
    41041 tggcttcatc atcatctagt agcagtagta gtaacaatgg taaaaatatg agagtggtag
    41101 caactgcata tactggtcac agtataactg caacaggaac aaaacctaag tggggaacaa
    41161 tagctgtaga ccctaaggtt ataccatatg gaactaaagt ttatatacct caatttgaca
    41221 tggtgtttac tgcagaagac tgtggtggag caataaaagg aaataaaatt gatatctaca
    41281 tgaatgattc aaaaacagtt tataactggg gaagaaaaac tatagatata cgtatattaa
    41341 aatagttaaa taatttatat ttttactgga aattatattt tgattatata gagaagaaac
    41401 tctttataga ttctaaaaat ataatttcca gttttttatt ttggatatgt aataaaacag
    41461 gtaaatttta accatgtata gataaaagct atttaaatta taatttacta tcatataaat
    41521 ctataaaaat tgttgcaaag agtcaaaata tatgatatta tagatttcgt tgagaaggat
    41581 ttcattatgg gagtggatgg gtgccggtgt gccctctagt cttcaaaact agtatgaggg
    41641 gttaagagcc tcttaggtgg gttcgattcc cacgcattcc cgccaatatg taaaaggtat
    41701 cttttaatta aaagatacct ttttaaattt attttaagat aatttatttt taataatata
    41761 taatgttttg tattatataa tgtaaatttt ctaatacaaa acattatata tttagataaa
    41821 aatctaggag tgtggaaaga tggaaaataa ttttacaacg agaactagtt ttctagttgg
    41881 agatgatggg ataaaaaaac ttaataattc aaatataata gtatttggag ttggaggagt
    41941 tggtagtttt actgttgaag ctttagcaag agctggagta ggcaatatta ctattgtaga
    42001 ttttgatgat gtagatataa ccaatataaa tagacaaata ccagccctac attcaactgt
    42061 aggaagatac aaagttgatg tcatggaaga aagaatatta gatataaatc ctaatatcaa
    42121 tataaaaaaa ataagaagtc tttataataa agatactagt gacgaaatac taactgaaag
    42181 atatgattat gttgtggatg cgatagacat ggtaagttcc aaaatacatc taattgaaac
    42241 ttgtgaaaaa aaaggattga aaataataag ttctatgggt atgggaaata aattagaccc
    42301 aactaaaata gtcgttacag atatacacaa aacaagtact tgtcctctag ctaaagttat
    42361 gaggaaagaa cttagggata gaggtatcaa aaagttaaaa gtagtatatt ctactgaaca
    42421 accaatagaa cttaagaaga aagtaatgaa tggtagaaaa gtaacacctg gtagtgtatc
    42481 atttgtccca tctgtaggag gtttaataat cgcatctgta atagtaaatg aactattagg
    42541 acaataagtt ttaaatattt taatttataa attttatata caaatttgaa ggctagaagc
    42601 atgaatacaa agcaatttta tattcatact tttagcctaa ttattttata ttaccttatt
    42661 ttatgtagtt gtagttttat tttttagatt atgtatctat ttcataatta tattttgtaa
    42721 atataatttc tccatcacta taaaaaacaa tatctcctat tctatctgtt ctataaattg
    42781 atacatggtt ttgttttaga ttattaataa cctccctatg tggatgacca tattgatttt
    42841 tatatccaca tgatattgca gctatatctg gactaatttt ttttataaat tctaaagatg
    42901 aagaagaatt acttccatga tgacctattt ttataaaatt aatattattt aatttaaaag
    42961 aatgtaaaat ttctttttca ttttcttctt cagcatcacc cataaataaa aaagaattat
    43021 cattaaaagt taatttgaaa actatagaat ttaaattaga ttcttcttgt atatatgatg
    43081 gacttaatac atatatattt atattgttat ctatgtttaa aacatcattt ttatagagat
    43141 gctgaataga taagttttta tccgtacaag aatttattag attttgataa gccttactat
    43201 cagttgattg ttcaggcata tatatggagt ttacattaaa tttttttata atattatcaa
    43261 gacttcctat gtggtctgaa tctggatgag ttgctattat aatatcaata gtttttattc
    43321 ttttttgtct aagataacta ataattatat tttcgctatc ttcatcacct ccatcaatta
    43381 atatattctt atttgtgggt gtttgaacta aaatactatc accttgtcca acatcaatca
    43441 tatgtataga tagtagagat tttttgtcac agccgattaa aagtgatatt ataataagta
    43501 ttgataaaaa aattttattt ctcaataaaa aatcactcca ttcattacat gtttatataa
    43561 atttatgatg ggtaatataa gatatatatg acttattata ttttatattt taaacaatat
    43621 aaatgaaatt aataccataa taaaattgga gttttttata tatacaaaat aaaattttta
    43681 aaattaagca ataaaaaagg taggaggatt ttatgttttt caaagatatt gaactaaatt
    43741 caaaaaaaga gttagaccca tattttgatt tagtagatta tgaagcttgt gagtactgtt
    43801 ttagtacttt atatatgtgg caacatgttt ataagacagg atattatata ggtgaagatt
    43861 ttgccgtttt agttggggaa tacgaaggag atagcttctc aatattacca cttgctaaaa
    43921 aagataaact tccagaagtt gtagattttg tccttgaata tttttctaaa aataataaaa
    43981 aaatatactt aagaggtatt actactgaag tagtagagtt tttaaaagaa aaatatccag
    44041 gtagatttga gtatatagaa gaaagagatt tatttgacta tatttatgat gcagaaagtt
    44101 taagaactct agctggtaaa aagaatcaaa agaagagaaa ccatataaac tatttcttaa
    44161 aagagtatgc aggtagatat gaagctaaat tattagataa agaaaacttt gatgagtgtt
    44221 tagtactaat gaaggaatgg gaaagtaata aggaagaaaa taatgaattt gatgaaagta
    44281 tggatgatga attaataggt atcaaaaaga tatttaacca ttatgacata ttaaaagata
    44341 aggtaaaagt gtttggtgtt tatgtagatg gaaaattaga agcttttagt ataggagagc
    44401 ttttaaatcc aaatatggca ttgattcata tagaaaaagc taatcccgat ataagaggtc
    44461 tgtatccatt tataaatcaa caatttttgg taagtgaatt taaggacgtt gagtttgtaa
    44521 atagagaaga agatttaggt attgaaggat taagaaaagc taaactttct tatcatcctt
    44581 gcagatttgt tgaaaagtac agtgttaggg aggcttaata gactatatgg agattaggta
    44641 tgctaaagaa gaagagatag aaagtataaa agatatttgg agttattgtt ttaacgatac
    44701 ggagagtttt atgaagtact attttaatga taaatataaa tctgaaaata ctgtagtagc
    44761 tttagatgaa ggaaaaatta tttcttctct tcagctaaat cagtataagt tattactaaa
    44821 tagcaaggta tataatacat catatgtggt aggagtttct acacttccag agggaagagg
    44881 agctggatat atgaacaaag taatgaaatt tactttaaac gaattgtata aaaaagggca
    44941 attagtttct atattgatgc ctattgacta tagactttat agaagatttg gatatgagca
    45001 ttgttacgac cagattgaat atactattaa cacagatgat ttaaaaaatt ttaagtcaag
    45061 tggaaaaatg ataaagtcta atttatcaca aattgatgat ttgatacaaa tagatagaac
    45121 ttttttaaat gaggttaatg gtaatgtgtt aaaagatgaa cattattatg aaaacttatt
    45181 taaagagatt caaagtgaag atggattttt atacattcat gaaggaaatg aaaaagatgg
    45241 atatatagtt tattttcttc aggaagataa aatgtttgtc agagagttat tttataaaaa
    45301 tatagatgcc cttaaatcaa tgcttaaatt tatatataat cacaatactc aatgtaagat
    45361 agttactata tctactccta caatagataa gataaggttt atattagaca accctaaaga
    45421 tagtgatata aaaataaaac cttttatgat gggaagagtt ataaatgtaa agaagtttat
    45481 tgaagatata gatattgaga aggatattaa tagctcattt aatttattaa tagaagacaa
    45541 gtttatagat gaaaataatg gtctatttaa aatttctata cagaataaga aggtatctgt
    45601 agagcagtta gataaaaaag gtgcagaaaa gcctcaagaa gattttgata ttaaattaga
    45661 tataaatacc ttaacacagt tatcattttc ttatatagat gtaaatgaag ctattttctt
    45721 aaatgatata aaagatgttt cagaagaaac actagaaaca cttaattgta ttttttctaa
    45781 aaaaaataac tatataaatg aatatatata ggtagagtac gttaaaagat tctaaaaatc
    45841 ttttgacgta tttttttgtt tagataacaa tttatcttgt ttaaaaattt tctatttgaa
    45901 aataatctaa ataatatact tttatatggg agtgattata attcaaataa gaagaccatt
    45961 attaattata ttaatgtttg tggtagctat atcatttatc attacaaata acacaaaaaa
    46021 cgacgaagaa cttaatgata agataataac tatacaagga gttgtcaaag gaaaaattga
    46081 aaagaaaaga tacaatcagt acaaggtagg ggtttttcta ataaatgatt atacaaaaaa
    46141 taaaaatttg aagattggtc agaaagttaa tattacaggt aaattcaaaa gtttagataa
    46201 aatgaagtat gatgattttg attatggaag gtatataaaa agtactggat ataaaggtat
    46261 agtgtatata aataactata aaattattga taaaaataaa ctttactctt taatagggga
    46321 aataaagttt tatattagta aaacttatag gtacttatat aagaaaaact cagattttat
    46381 aaattctata ctattagcag aagttgaaaa tttgactgag gaacaaaaag aaatttttac
    46441 cagaactgga actagtcatg taatatctat atcaggtctt catacaggaa tattatgtgt
    46501 aattatatcc tttctattaa gaggtataaa taaattgtat aaattattaa tactgtcgat
    46561 ttttataact ttatattgta taatggtagg tgcgtctcca tccataatta ggtctatagc
    46621 atttgttatg attttttatt tatcaatatt tattgataga aagaaagatg gaatatcggc
    46681 attgtctcta attgggataa ttttaattat gaataacccc tatgttatat ataatgtaag
    46741 ttttcaattg tcttttttag ctacactttc tatattaata ttctataata aaataaatag
    46801 tattataaaa ttaagtatgg tatcattgac aatatcatca aatatattaa ctttacctat
    46861 aatttattat acatttaaag gtataccatt gctttcaatt ataggaaatt taattatagt
    46921 gccatttgtg ggagtaataa tgtatttaag tattgcaagt ttaatcgtat ttaaagtaag
    46981 tgtagtaata gctaaaatta tatctttttt taatagtaca tttatagaaa gcatattttt
    47041 tttactagaa aaaatcagca atttaagttt tgcatacatt aatatagaaa atcctaaatt
    47101 ttatattgtt gttatttatt acataggagt gtttttttac atattttaca tagaaggaaa
    47161 agagataaag gagcaagaga atgaattaca aggatattat aaggaatgta aaagagaaaa
    47221 actttgaaaa aatgtatctt ttttatggaa gagagtatta tttaattgag aatgcaataa
    47281 aagcatttaa agatagtcta aacgagggaa tgcttgattt taatttagat ataatagatg
    47341 ggaaggaaat agtcttaaat cagcttataa gctctataga aacacttcca tttatggatg
    47401 ataggaagat agtaataata aaagactttg aactattaaa aggaaagaaa aagaatttta
    47461 cagatagtga tgagaaatac ttaatagagc atttagacaa tattccagac accacaacta
    47521 tagtttttgt tgtatatgga gatgtagaca aaagaaaatc attagttaag aaaataggaa
    47581 acaatggaat tgtttttgat tgtgataagc tttctgatat ggatttgttt aaatggataa
    47641 aaaaatcttt tgctttaaat gatgttataa tagataattc tcaaatcatg tattttattg
    47701 aacaagaagg atacagagat aagagtagtg aaaagacatt atctgattta gaaaatgaaa
    47761 taaataaaat aagttcattt gttggtaaag ggaataatgt aaccaatgat gtaattgata
    47821 aattatctca aaaaaaagtt gagaatgata tattcaaatt aatcgattat attggagaac
    47881 aaaatgcttc taatgcaatg aaaatattaa atgatatgat acaagaaggc gaatctgtat
    47941 taggtatatt ttctatgata gcaagacaat ttaaaataat tatgcaagta agacagttac
    48001 aacttgatgg atattcaaca aaacttatag ctgataaatt aaaaatgcat caatttgttg
    48061 taggaaaagc attaaagcaa actaaaaatt tttctgatga tataattgtg gaaatattaa
    48121 actatatatt agaaagtgat tacaaaataa agacaggtct tataagagat actttagcag
    48181 ttgaaatgtt ggttagtaga tactgtaaaa gagaagcaat ttaaaaaatc tatatattaa
    48241 taaaaaataa atagcaagat atgttatagt tcagagtaga tgtaagctaa attaagtttg
    48301 atatacaatc aactataata tgtctaacta tttatttttt attgtataaa tttacaaaat
    48361 aaaaaacccc tacatagggg ttattatata taagaaatat aaactggtaa ttaagcgttc
    48421 ataccgttta atttttgagc taatttagct acttttctag ctgcagcatt cttatgtata
    48481 gttcctttag aagctacttg gtatattctt ttttgagcgt attggaactt agcaacagca
    48541 tcctctctgt ttccagctgc aacagcatct tcgaatcttc ttattgcagt ttttatttga
    48601 gattttctaa ctctatttaa agcagttttc ttttcgataa cacttattct tttcttagct
    48661 gattttatat ttgccaccgt gttcacctcc ctgtattttt ttatcatatt catcgtcaac
    48721 atattagatt ttaacagaaa taaatctaaa aatcaaggat tattatttat atattttaat
    48781 aatgtttttt attttgattt tttagactgt aaattgtgta taaataattt gcaatatctt
    48841 gtttttaaat tggtatattt tgtgttttaa atattttgac atatataatt aatatttcat
    48901 tttgtaacaa atatttga
//
LOCUS       DAMJVG010000021        48815 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.021, whole genome shotgun sequence.
ACCESSION   DAMJVG010000021 DAMJVG010000000
VERSION     DAMJVG010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 48815)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48815)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48815
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.021"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            <1..665
                     /locus_tag="PC512_001346"
     CDS             <1..665
                     /locus_tag="PC512_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF2441106.1"
                     /translation="ISKEPSGRYYVSLCCTDVDIEAFENTNNQIGLDLGIKEFCISSC
                     GEFIENPKYLKKSLNKLAKLQRELSRKTIGSLNRNKARLKVARLQEHIANQRNDFLQK
                     LSTKLIKENDIICIEDLQVKNMIRNSKLSRLISDVSWSEFIRQLEYKANWYGRQIVKV
                     GKFFASSQICNKCGYKNEEVKDLNIREWICPSCNETHDRDINASINILKEGLRLITIQ
                     NK"
     gene            816..2033
                     /locus_tag="PC512_001347"
     CDS             816..2033
                     /locus_tag="PC512_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HDF2441107.1"
                     /translation="MLIGLIAAFGLVLQKKKASDVIKGSLLAAFGIIIMETGTGMLVS
                     SIAPINGAFQSISGGAVTKGLSDVTFTASYGGIIGLAMFAGLAIHLMIARFTPIKTIF
                     LTGHMLYWFPFIFVASGVEAGLNGGVLITFAAVLSALYWSIMPWLLRKYVFDVIGDDS
                     FTLGHPSGCLALISGFVAKLVGNKEKSTEDINIPQSLSFFREISISGGMAVFLMFIVV
                     GIVIPGAFKDSNEFIGTYAIKQGLSFGAGLIIMLHGVRMLINQIMPAFQGISEKVVPN
                     ALPAFDCPILFNYKPNAVLIGFLVAMLTSTAMILIYNYFNVFNLLLIPLVITSFFECG
                     AAAVIGESQGGIRGAIIGTAIAAIFMVVLVGISAVIYSGTIQNWILIFGGNDLSLFGI
                     ISRFIGSLFGGIL"
     gene            2036..2776
                     /locus_tag="PC512_001348"
     CDS             2036..2776
                     /locus_tag="PC512_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDF2441108.1"
                     /translation="MKFKYIDEIRRLIDIIENEEKVNMEKAVQIFVEAIESKNAIFSF
                     GASHAGILTEELFYRAGGCVLINPVFAKSLMLDTAPITHTSKMERLEGYGTALADKTP
                     IKKGDVVIVHSVSGRNPVSIEFAMKAKENKAIVICITNLSYSKSVSSRHSSGKKLYEV
                     CDLVIDNHGQKGDACVEIDGLNQKVSPTSTVIATTVMNSIIAQATQELVNKGLKNPPI
                     FYSANIDGGDELNKKIFDEYKSVIHYEY"
     gene            3099..4409
                     /locus_tag="PC512_001349"
     CDS             3099..4409
                     /locus_tag="PC512_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HDF2441109.1"
                     /translation="MKKENKMEGIKVGMLKKLCSLAMVAIMTTTLITGCSSGNGKDSK
                     KDGEKEKLVLWMPPVENNMKEVWDPILDKFEEKNNCEVDLQIIPWDNYSEKFATAISA
                     GEGPDVGYMYAEMYPQFIESGAVEDLTNYATKEDKEQSIYIKTSEMMGGMYGMPFQAA
                     NPGVLYYNKDILEKLGEKPPKTWEDFKRICKKATQDTDGDGKIDQWGLAQGWGAKTFG
                     NLNWNWYPYLWQAGGDIFNDDLKSVKFNDKSGLEAANFLKELQAYVPEDSLSKDSNEM
                     IESVFGPGKAAFTIMLSSAATSVFDESFPDLNWGFVTGLEDKKAATFGAVDHLSLMSS
                     AKNKELAYKLIQHMLSVESMTEFHKAIPRAPITKGEPYQGDERFKEMVENDKNVYRPL
                     VVGPHGVEIYEYLWKELQTMISGDKTPKQALDDAAKYSNDLLAQ"
     gene            4507..5424
                     /locus_tag="PC512_001350"
     CDS             4507..5424
                     /locus_tag="PC512_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDF2441110.1"
                     /translation="MENLVREFEENSKRKKTKLNIKPYMYILPLGIILVAFYVIPIIM
                     SIYFSFTKYNIISPATFIGLENYKKLFTDETLKVSIINTIKFTVVVVPCQTILSLILA
                     VWITGKGNSKIASFAKGAIFIPVLSSMVLIGMVWRALLNGEGSIIYQVLGAFGIESSK
                     LLGDSKTALPTLMFISMWKNIGYFMVIYISAIMNLPKHCYEVAKVDGATKLQEFIKIT
                     VPLLKPTTIMVVFLGSIWSLQVFDLIYTVTGGGPGISTMSIVMHAFNLNFKNFNSGYA
                     MTVANVLFLLIAVVSILQNKLVRRDNSDF"
     gene            5440..6249
                     /locus_tag="PC512_001351"
     CDS             5440..6249
                     /locus_tag="PC512_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDF2441111.1"
                     /translation="MKTARRLLSDGLLLFIACASLVPFIYMLIISLKITYNSYSLDIS
                     FSTVTLQNYIDIFTKKGFAQYFFNTAIVSFSGVLLNLVFSTLAGYSFAKMDFKGSDKL
                     FLFMIMTLIIPSQVTMIPLYIIMKHLGWINSYLALIMPIPTAFGVFIMRQAILGVPKE
                     LLESAKIDGCSDFRILIQIVLPLIKPALITLAIFTFMGAWNEFMWPLIATTKDTMRTL
                     TVGLSTLKTFQITNYGQMMAGATITFLPPFIFYLILQSKFVEGVSLSGIKG"
     gene            6307..8055
                     /locus_tag="PC512_001352"
     CDS             6307..8055
                     /locus_tag="PC512_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4091 domain-containing protein"
                     /protein_id="HDF2441112.1"
                     /translation="MEISYVLKDCTFKHNKYSVVEAETWKDKDLDIVVAKGEKFAFQI
                     MLKATEEFNCTIDKSSAISWKGLGNRVRLALNMPNSLENNFSINILGYVQDDTKAFVN
                     DAILRDKDVLVEQYLPQTFWIEGQVPEDFEENNLDIGIDIFKSFGYEDEEKVCTIDVP
                     VKVRNVVLKPLDESKFFLDLWQHPSCLARMYKVELWSDIHFEIVDNYLKELASLGEKV
                     ATVIVSDYPWAGQSCYKVYKNPSNLYEYNMVSVSKGLDGKIKCNFESMDRYISIADKY
                     KMAKEIDLFGLLGNWCAGEFGNPVEGYKDPIRVRYFDEKDKVFKFINNTNDLKEYIGL
                     VLNHLIECGLWDRVRIIADEPNNPEVVKECIEFINSTVSTHQVKYKSATHDQNFLDRA
                     KDEIDDMSINLKLTIQNYKDIESLKKKINDKGGILTWFVCCFPEKPNSFLSSPFVENR
                     IIGWYTYYFGLDGFLRWDYNLWTEDPWKDSSYKFPIWKAGDMFFVYPGKDLKPVRSVR
                     MENLRFGIQDFELFTMLEKEKGREYIEVELMQELLNKKENAEIKGFGDIELGYSLDNW
                     GYDKVKKYVLELLDRV"
     gene            8317..9339
                     /locus_tag="PC512_001353"
     CDS             8317..9339
                     /locus_tag="PC512_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 5 protein"
                     /protein_id="HDF2441113.1"
                     /translation="MFGGINIKRIGIIIMFFLSISFIGFYLVIRDNSDTVKMQRGINI
                     GNALESPKDFPWDVKMSNKFFDDIKDAGFDTVRIPVRFSDYTSDSDNFKIDEEFFKKI
                     DKYVDYALDKDLIVVLDLHHFEEIMKEPRVHKEKFLKIWQQIANRYQKYDKKLVFELL
                     NEPKENLYSQLLNEYIEEAIKIIRKTNPKRTIIVGPYNFYQIDYLNELNIPKDSNIVV
                     SFHYYEPNDFAFQGNIYHKGFEHLSNITWEGTNEQMDYLKKRFDTVENWANKNKVKIF
                     LGEFGITKEAPEASRRAWIKAVREEAEKRNFSWAYWELASGFGIYNQIEGTWDRDILS
                     ALIEKR"
     gene            9344..11650
                     /locus_tag="PC512_001354"
     CDS             9344..11650
                     /locus_tag="PC512_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDF2441114.1"
                     /translation="MKKNSKKILITLTIITNVIYILWRIFYTVPKEEGKFALICAIIL
                     LFVEIMGMMEMFVHYYGMSNIEYPEKPIISEELYPHVDVFIATYNESVDLVRKTVNGC
                     IHMQYPDKKKVHIYICDDGNREEMCILAEKMGVNYITRTEREGAKAGNLNNAMQHTNS
                     PLIATFDADMIPMHDFLIATVPYFLKNEQAKKDGEKEEYEKVGFVQTPQSFYNPDLFQ
                     FNLHSEGRIPNEQDYFYRDIQLARNRTNSVIYGGSNTVISREALEEVDGFYTYSITED
                     FATGILIQSKGYRCYAIPEVHASGLSPTDLKSLIKQRERWARGCIQTGRRLNILFRRG
                     LGFWQKISYISSITYWYASIKRFVYIMAPILFSVFNVIVVKCTLLQVLVFWLPMYILS
                     SLSLKIFSQNIRNTRWTNIYETIMFQSLMPAVILETFAISKNKFSVTNKSKLEENRMY
                     KFLQGIPYFIYMVLSIIGILKMFVAIFKMSSMTYSVVLFWLIGNLFNLVMATLFISGR
                     QQLRKSERYIAEIDFKLKQNSYVLSSKTIDISENGFAFLLENPEYISPEEEFEVEFRE
                     KSGNEMYIANMKAKIVNVVEVNSKWKYAAYITHIEDSEIDNWMCIVHDRIPTLPMTIS
                     NQLGFFDDLQINVKKRIEKTRTLSRRSPRINMNFQMDIKNTGKLRIVNFNYQYVLLNF
                     ENKSIYPKEIALEINENIVLECDLCEGKIDERGILYKVNNIDSIMQNFFLRDEMMDWI
                     LQNKKILDSKPSEKKEKSIDEFEPMEYI"
     gene            11622..12737
                     /locus_tag="PC512_001355"
     CDS             11622..12737
                     /locus_tag="PC512_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441115.1"
                     /translation="MSLNPWNIFRRDEMKTLKVFFCSTKYLILVFIFFINTTFISSAT
                     SDKILDLSFKKIETDLSSKITYEDTGVKIETDSSKSDKERYLYIYQNIKENWSMYNNF
                     YIEIQNKNKSSQRINLSIQSKNMLEFRLKEGSEVFLEGKNIIYSDKIKEGCIEVPGEF
                     EGKIYVNFNSLINEESNVVLDSNMLSNIVSWGITFIPSDEEHNIVIIKKISLLSEEKL
                     RFLNNIKIIGDEEVQIPVLGQSISQYEVLGLKSDSKIKYSLMGKQDNVSISQNGKLTL
                     SNKAKPGQIILQVNVDDKFKIGKKITLTESWSINKKDKDGVPYTLVSPEQSPTVQDMK
                     KINFMNNIITFVRILFVSLVIICFGIYLYWKKCSKTK"
     gene            12755..14173
                     /locus_tag="PC512_001356"
     CDS             12755..14173
                     /locus_tag="PC512_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBOAT family protein"
                     /protein_id="HDF2441116.1"
                     /translation="MLFSSLIFLFYFLPITLVLYYVFRFNRTIQNMILLAVSLFFYAW
                     GEPKFVVIMIVSIIMNYIFGLLVDRYRESKIKVKVFLVLMCAYNIGVLFIFKYLAFAL
                     RNISELISTELTIPNIILPIGISFFTFQGMSYVIDVYRRHGEVQKNPFYVGLYIAFFP
                     QLIAGPIVRYESVAEQILNRKETWNKFSIGTCRFITGLGKKVLISNNMAIVADYIYTM
                     NSQGEIAASLAWLGSIAYTLQIFFDFSAYSDMAIGLGLMFGFKFEENFNYPYISKSIS
                     EFWRRWHISLGMWFKSYIYFPLGGSRVANKDIMIRNMFIVWLFTGIWHGAEWTFVIWG
                     ILNFVFLIIERFIMFEKIENHNFIKHIYALLVVNFGWVLFRSPNLKEAYNYFKAMFGG
                     NGAIWSDYTYMFLKEYWVFFIFAFIFSVPIAKKINKFVVEQAKYSMIFNVFYPISAIL
                     LFFISVTYLVTGSYNPFIYFNF"
     gene            14188..15396
                     /locus_tag="PC512_001357"
     CDS             14188..15396
                     /locus_tag="PC512_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441117.1"
                     /translation="MNRFFKVRLITAIMFLIILFAFSIFNVCYSGKDTIQEIKNSIAE
                     KSSLKDTISSIDNTVNDKVIYKNTFIETYGYLQKLMGKNEFSKFSVVKDTSGKMHYTY
                     FAKAPNPVGVIADRVRKFSDEMEKQNTKLVYLMTPDKYIKGVTKFPKGIPYSYSNETA
                     DNFLNQLKKYNVDYIDFRENILKSGIPKDDLFFKTDHHWKVETSFWAFGELVEQLNKK
                     YNMNLDENHYYRDKDNYNSIVYPKSFLGSMGRKTGILYGGIDDFTLIYPKFKTNYTYY
                     TDSKSQKFELKGRFEESLILSYPFNADLDLMDGQSDKYFTYLLGNRPLVKIKNIENPD
                     GLKVLFVKDSLIVPTAAFFSSVCSSIDMIDPRYYDGDILEYAKSHDYDFVFISVYPQN
                     LTKEFFPFCE"
     gene            complement(15470..16858)
                     /locus_tag="PC512_001358"
     CDS             complement(15470..16858)
                     /locus_tag="PC512_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:dicarboxylase symporter family
                     transporter"
                     /protein_id="HDF2441118.1"
                     /translation="MESSFLSQFLMITDFKTIFFIILLLGTFFIVRQFEKKKIKFSLR
                     TIYATVLGLILGIIIQAFAGFPNDTTQVTWLQEVSKWYSLFGSGFMDLLKMLVVPLVF
                     LSIIKVIINMKDNNLGTLTFKSLGMLLATTAIAAIVGIIVANIMKLGVGANMPTLVEN
                     QELKEINSLVDTLRGLLPSNPVMAMANGNIVATIIFATFIATSIKRLSKKHFETIKPF
                     IDFIEASYKIIVSVSMTVIKFMPYAVVALLANTITSQGISSIVSVLQFILALYISVAI
                     LFIIHLIFITLNGLNPITYIKNSTEALLLAFTSRSSLGTLPVTIESLVQNHGVDEGVS
                     SFTASLGANMGMNGCAGIYPALMAVTLANMAGVNMDMSFYVMLLIVITISSFGIAGLP
                     GTATMAVSVVISGVGLGSYFPLVGGILAIDPILDMGRTMINVNGAMVSSITVGKSLGK
                     IDKEVFSKKNIS"
     gene            17199..18533
                     /locus_tag="PC512_001359"
     CDS             17199..18533
                     /locus_tag="PC512_001359"
                     /EC_number="1.8.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-disulfide reductase"
                     /protein_id="HDF2441119.1"
                     /translation="MRVIIIGGVAAGMSAAAKLKRIKPEYEVVVYEKTEIVSFGACGL
                     PYFVGGFFNDADELLARTPEKLREAGIDLNIFREVVEVDSESKKIKVKNIKTDEIYED
                     YYDKLMIATGARSIMPPIKNIKLKNVSTLKSLYDGEYLKKLLSNEDNKRVTIIGAGFI
                     GLEAVEACKKLGKDVDVIQLEDRILPQVFDKEMTDVLEEEINRHNVNLHLDEMVVELC
                     GEDKVEKVITNKGEIDTDVVIIATGVRPNTEFLSNTNIKMLKNGAIVVDEYGRTSVED
                     IYSAGDCATIKNIVSNENVYVPLATGANKLGRIVGENLAGREVSYQGSLSSSCIKIMD
                     MEAASTGITEKQAKDLGINVKSKFISDYNQTHYYPGRNKIYVKLIYDADTKVILGGQV
                     AGFKDAVQRANVLAAAIFGKMTTNQLGMLDLCYAPPFARTWDVLNVAGNVSK"
     gene            complement(18675..19592)
                     /locus_tag="PC512_001360"
     CDS             complement(18675..19592)
                     /locus_tag="PC512_001360"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011969064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HDF2441120.1"
                     /translation="MIDLTLLGCGGNVPMPNRFLSSVFINYKGRKILIDCGEGTQVSM
                     KLKKCGFKDIDLICITHLHGDHIFGLLGLLSTIGNSGRTSDLTIVGPVGIVDCIRSMR
                     NLVEYVPYTLKIIENPQGNFSLDNKVLRNLEISTISLEHSIECLGYSFNFRRNPKFDI
                     DKATKNEVPKILWNKLQEGQNIVLDSKQYTPDMVLGELRKGVKISLTTDTRPIESIPD
                     FIKDSDLFICEAMYGDDLDISKAVRNKHMTFREAANLAKLGNVKQLLLTHFSPSLDIP
                     SMYLENATNVFENTILGEDRLSLRLNFDE"
     gene            19800..20684
                     /locus_tag="PC512_001361"
     CDS             19800..20684
                     /locus_tag="PC512_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4846 domain-containing protein"
                     /protein_id="HDF2441121.1"
                     /translation="MKVLKKITILSLITLTLVGCSNGEDKKVVEGSKKIQNSKKDEQP
                     IIVHKDANILKDRYEPPKGFKRVDVEKGSFESFLRNTKLKNYGEKVKYYDGRTKESKG
                     IYDSVFDVDIGNRDLHQCADAIMLMRAEYLYQNKLYDEISFDFVDGFKAKYSKWAQGY
                     RISVKDSGSSWYKATEYSTSYESFRKFMDIVFAYSGTLSLEKELEPVKVEDMKIGDVF
                     IVGGSPGHASIIMDMAENEKTGEKVFMIAQSYMPAQQTQLLINRKNPNLSPWYSLDFE
                     GDLTIPQWTFKRDQLKRF"
     gene            20897..22738
                     /locus_tag="PC512_001362"
     CDS             20897..22738
                     /locus_tag="PC512_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase C-terminal domain-containing
                     protein"
                     /protein_id="HDF2441122.1"
                     /translation="MKIRRYLILVIIILITTSQSFISYGLERFEEITIFHTNDIHGRY
                     AEGDDHIQIGNLATLKKETPNSILVDAGDCLHGLPIVNMDRGKSAIELIKCAGYDYIT
                     PGNHDFNYGKDRLFELSKSANLGENTLKFLSSNIFENGKKVFDSNDIKEIDGIKIGFF
                     GLSTQETKSKTGFKNVEGLEFKNPIESATEQVNELKGKGANVIVAICHIGTNSLSKPN
                     SIDIANEVQGIDLIIDGHSHTKFENGKQVGDTLIVSAGQYLENIGEIKLTLDTNDVEN
                     IKIENKSVRLIGKEEALKYKLDSAVSKKVDEIKEQQEKILDKVIGVTTNTLDGSYENV
                     RTKETNLGNLISDILLDKTKADISLFNGGNIRDTIEKGNITRRDIVDVFPFSNTIVTK
                     ELTGAQIKDVLEHGVKLYPEKSSAFLQVGGISYYFNPKQKEGEKITNIQKEGKPLDLN
                     KKYVVATNDYIASGGDEFPCFSKEPVLKEFGNLESAVIEYIEYKKEISKNVDGRIGIK
                     SKDELISKNHESDLILSENEKNINDNEENLSNNIKSSDSDKNKSLDKTSARESSNLGI
                     SKREAKEKSPKTGDLGFSNSIIIFIVSSTLICLLNFNQKELKDKKSK"
     gene            23043..23750
                     /locus_tag="PC512_001363"
     CDS             23043..23750
                     /locus_tag="PC512_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2441123.1"
                     /translation="MNNILLLEDDKSLNRGISFKLKKEGYNVFSAFGIEEAKNIFAKE
                     EICLIISDIGLPDGSGFDFCEEIRKKSDVYIIMLTALDEEVDIVTGYDLGADDYITKP
                     FSLMVLISKVNALMKRVNTVKNYTLLVCDDLFFYYIENKLIIRTDDKEEEIILSKTET
                     KLLKYLMENSMQTLTKEQLLESLWDSSGNFVDDNTIAVNIRRLRQKVEKNPSEPKYIK
                     TVRGVGYMWGERSIKKC"
     gene            23744..25054
                     /locus_tag="PC512_001364"
     CDS             23744..25054
                     /locus_tag="PC512_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2441124.1"
                     /translation="MLKNMNLKDGLSVKDDYIMRRVIVYSVLSVLIVTLVFILFEYSR
                     LHKLYEHQIKNTQNIAGILIEKYPNDEIDIVNSIYNSDYSKVSTGEKAFKKFGYGLEN
                     KMSNDKNFSLYLKSFFKESFFIFLMMFIVVIGIIYYFIRYINKRLSKIYFIVDKMSQE
                     NYLKDTTESEETGYLVEYNEYFKEGIFSKINNCLYELNRSLKIKFIKLEKEKESVKSL
                     VTDISHQLKTPLASLKLYNTLLIEEELEEDEANEFLLTNKASINKLENLINSLVNISR
                     LEISMINIKKEDNDIKNTILNAVKSVTPKAKSKSITLNLNEFNSRIIPHDKKWTEESI
                     FNVLDNAVKYTQVNGEINISVEETANFFKIIIEDNGIGIEKNEFNNIFKRFYRGSADE
                     IESVEGSGVGLYLSRKILEEQGGNIIVSSKVGIGSKFSLFLTTM"
     gene            25171..25854
                     /locus_tag="PC512_001365"
     CDS             25171..25854
                     /locus_tag="PC512_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2441125.1"
                     /translation="MKILYTENLSKHYGKGESLVRALDNVDLEINEGEFVAIIGKSGS
                     GKSTLLHMIGGLDIPTSGKVYIDNKNIFTLKEEELAVFRRRKIGFIFQSYNLIPSLNV
                     WENVVLPIGLDGREVDESFIKELLKSLGLENKHDVLPNTLSGGQQQRVAIARALATRP
                     AIILADEPTGNLDSKTSDEVMSILKSMSKKYSQTLVMITHDDSIAQMADRVIFIEDGR
                     VSKVGDKND"
     gene            25847..28234
                     /locus_tag="PC512_001366"
     CDS             25847..28234
                     /locus_tag="PC512_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDF2441126.1"
                     /translation="MINTTKIAKSNLKQNKSKSILIIITIILSTLMLSSIGIYIVDAG
                     AYQKENTIKYSGNYQGILANVDEKQADILSNHADVELTGEMNGVGVEKLEDDSNISLA
                     YMNEDALKLNSFEFIKGKLPSKENEIVLDSGALKALGYKNKDLGEKIKISYDDYKNDK
                     KIEKEFIISGILKTSEISEAGKYYYAIISESYMRNTRDMSQEDFNIYVKFNDKSNLSI
                     EQAKEKLDKIANDIGLDTINTAVNENYINALKPDMETIMGGVFVGLVIVLSSILVIYN
                     IFYISIVTKVQEFGKLRAIGATKKQIKNIVFKEGFILAGIAIPIGIILGYVLANIIIK
                     SFMDIDVKSSRLPVILSVVVISFISVVLSLLKPMKVASKVSIVDAVRYTGNKISNKSK
                     RKGYKNINLKRLSHANLERNKKRTYMTLASLILSGTIFITVSTALESFDAEKMAREHF
                     PYDIEVRLSGYEMNSDKNPKDNLNILQMDNPLSKDFFNQIKNMEGIKRIESARSVKIG
                     MEDYDVEFKYDLLQSINENDVKSLNKNIIDGKINLERLQTGDEIVITHVDTAKEMGVK
                     AGDKIRLTLYDGDKKIKKEFKVQAIAMGVPSFGIGKDFIDRTLKYDSTSSLGIYTEEG
                     KYQEIKDSIKKIAKNNGFLETDFIDSRIESNKATISFIKIMGYTLTGIIGVIGFMNLV
                     NTMITSIVTRKKELGMLQAIGLTNKQLVKMLNSEAIYYTSGMMIGSILFGGILGYIAV
                     IFLKKTGLSYATYSLPIVPILLMIVCILIAQFITTYLIGRSFNKESLIDRVRYSE"
     gene            28514..29656
                     /locus_tag="PC512_001367"
     CDS             28514..29656
                     /locus_tag="PC512_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HDF2441127.1"
                     /translation="MNKKINYAPGPTETRENVRLARAEKTTNPDIDIDFVEFYKKTCE
                     KFGNIIGTKNDVYILSGEGILGLEAACASLTEKGDRVLVIDNGIYGEGFKDFVTMYGG
                     EYVLFSSEYTKSIDIDELKAFLDEDSNFKYATVVHCDTPTGVLNDVSKICPLLKKYGI
                     LTVVDSVAGMVGERLSVDESKIDIILGGSQKAISAPAGLTIVGISQDAKNCIKNRKTD
                     VIGFYCNLNIWEGYYEKKYFPYTMPISDIMGLDKALDNILEEGIENVLNRHEKIAYSV
                     RKSIEEYGLELFLEEGYSNTVTAIKIPESIGALELTDYMLKNYNTLVATSLNQYMDTI
                     LRIGHMGENANLNKIEHVLNVLDKSLSALGFKGNGNLLNLFNKYYF"
     gene            29675..30199
                     /locus_tag="PC512_001368"
     CDS             29675..30199
                     /locus_tag="PC512_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDF2441128.1"
                     /translation="MEVTAKQKFTTKDMVETSLLIALVFIATKFINIRLPISINGGLV
                     HLGTAMLFISAIVFGGKKGALSGAIGMSLFDLISGWTLWAPFTFIVRGVMGYLLGKIA
                     WANGNNGNNFLINVIGICVSSIWMLFGYYVTEVILYGNFIVPLTSIPGNLMQVLIGLI
                     IALPISKVLKKCIK"
     gene            30299..31117
                     /locus_tag="PC512_001369"
     CDS             30299..31117
                     /locus_tag="PC512_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF2441129.1"
                     /translation="MLSVTRYSIKNVRLKPWVKFIWYFETKSNILLNNKLLPTDSIDI
                     ILNLSDVMEYKIENQDYTASNMHFNGIRDKHGFIIQHGNIRVIGISFYPFGLYPFLKI
                     PISEFNRQIVDLEAVSQLFAKKLEESLNPTQSVEKIVLYLEEVLLSILEEDLISNKYV
                     KLLNSFIYVNRYSNIKAFCDDTNINIKTLERICLKYTGYTPKILKRIYRFKMASNQLI
                     YNYKDDELFDFIYENEYYDQAHFIKEFKKFSGTSPIKFIGENKTIKENIKYSYL"
     gene            31195..31506
                     /locus_tag="PC512_001370"
     CDS             31195..31506
                     /locus_tag="PC512_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HDF2441130.1"
                     /translation="MKIITEIVEFNVEENLSKEEFIEIVNDLELKFHSIQSGFIDTEL
                     LYDEKSQKWIMIQHWESIEDLKSASSKMFKDSSTEKFRKALKNQTVKMNIIPQIKSWK
                     L"
     gene            complement(31633..33636)
                     /locus_tag="PC512_001371"
     CDS             complement(31633..33636)
                     /locus_tag="PC512_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase C-terminal domain-containing
                     protein"
                     /protein_id="HDF2441131.1"
                     /translation="MKSQKRFKILDIDVYLQPFESDIKKRMKHYENMKSKTLKNYKDF
                     SSFANAHLYYGFHQTNDGFFYREWAPNADSLSLIGDFNNWNRKSHPLRKIGSGNWEIF
                     IPGQNSLPHKSEVKVQVTANGKTFDRIPLYIKRVIQKDFGGFNGQIWQPKTPFIWTDN
                     DFDLKNITYPLIYECHIGMSTESESIGTYNEFTEKILPKIKKAGYNTIQLMAIMEHPY
                     YASFGYQVSNFYAISSRFGTPEDLKNLINTAHSMGIAVLLDLVHSHAVKNTLEGINEF
                     DGSEHQFFHSGSKGNHPAWGTKLFNYGKPEVIHFLLSNIKFWLNEYHFDGFRFDGVTS
                     MLYHNHGLGVSFDSYEKYFSMNTDIEAITYLQFANELIKEIKPNSISIAEDMSGMPGM
                     CIPIKDGGIGFDYRLAMGVPDFWIKTISNLSDEDWDLGKMWYELTTRRPGEKNIGYCE
                     SHDQALVGDKTIIFWLADKEMYWNMEINSNNHVINRAISLIKLIKLITFSLAGEGYLN
                     FMGNEFGHPEWIDFPREGNNWSYKYARRQWSLSEDNNLKYKQLLNFDKSMLELTKYSD
                     IFIQNSHELIHMDNDKKILVYSKGKYLFIFNFHPNLIQSVDISKFQNTNYKTILNTDM
                     VEFGGNTKKENLRDYDVYFSSTPPSSKMPIASRTAIVLLDSSI"
     gene            complement(33789..34427)
                     /gene="recX"
                     /locus_tag="PC512_001372"
     CDS             complement(33789..34427)
                     /gene="recX"
                     /locus_tag="PC512_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HDF2441132.1"
                     /translation="MGIITKIEQQKRNDDRVNIYVDDKFFIAIFKELVYTFNLKKGNE
                     INEEELKPILDDEMYIKAKNKALNILSHADQSEKKLKEKLSSEFDENIIERVIDFLKS
                     YNLVNDSVLAQKIVNTNVNLNKCGKNRIKQNLYNKGINRSTINEAVSELDKDTEFENA
                     MYLAKKRYERVKKEDKKKIYQKISQHLSYKGFDYDIIKRVLNKLLNFDEYDI"
     gene            34703..35392
                     /locus_tag="PC512_001373"
     CDS             34703..35392
                     /locus_tag="PC512_001373"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HDF2441133.1"
                     /translation="MRSENLVKMAELKNTEKLEKFNRHKGKIKIGILGGTFDPIHYAH
                     LATAEFIRDKYDIDKIIFIPSGNPPHKLCITTDKYDRYNMTLLATESNEDFLVSKVEI
                     ERKKRTYTIDTLKYLKKKYKNADIYFITGADAICSVEEWKDVKKNFELATFIAATRPG
                     ISLLRSQETIEKLTKKYNADIITVYVPSLDISSTYIREQLNEGKSIRYLVPENVENYL
                     YENKLYQYGDD"
     gene            35393..35965
                     /gene="yqeK"
                     /locus_tag="PC512_001374"
     CDS             35393..35965
                     /gene="yqeK"
                     /locus_tag="PC512_001374"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HDF2441134.1"
                     /translation="MNLENINQRLNQMLPVGRLSHSKNVAKCAEKLCEIYGCDKEKAY
                     LAGMIHDCAKYLSDKEIEDYVNKYEIYLDPIEDGNRSLSHSVIGAYICEYEFEVEDED
                     IINAIKYHTTGREDMSLLEKIIYIADLIEEGRKFPVVDTLRELAYGGKLDEALLTSFN
                     NTLMFVINKKEEIHPRTVMARNYLIKEKLL"
     gene            36082..36432
                     /gene="rsfS"
                     /locus_tag="PC512_001375"
     CDS             36082..36432
                     /gene="rsfS"
                     /locus_tag="PC512_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HDF2441135.1"
                     /translation="MTVEQMTKIAYDAIEDKLGQDTVIINIGKVSSLCDYFIITTASS
                     QRQVKAIADNVEDELAKLGLEPRGKEGQGTQTWVLLDYGDIMVHVFNEENRGFYNLEK
                     LWKDAPYIDIDTLA"
     gene            36786..39206
                     /locus_tag="PC512_001376"
     CDS             36786..39206
                     /locus_tag="PC512_001376"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HDF2441136.1"
                     /translation="MSVYNFKEVESKWQKIWKDNNQYKMDTAQTEKPNYYTLEMFPYP
                     SGKIHMGHVRNYSIGDVVARFKKMEGYNVLHPMGWDSFGLPAENAAIKHGIHPHKWTM
                     ENIEEMKEQLNLLGISYDWDKEVATSTPEYYRFTQEIFLKFLEHGLAYKKKSYVNWCP
                     SCETVLANEQVVQGACERCKATVLKKDLEQWYFKTTEFAEELLNDLDTLDGWPEKVKT
                     MQKNWIGKSTGADLVFDIDGTDKSMTVFTTRPDTTYGVTYMVLAPEHELVKELVAGTE
                     YEADVEAFVQKMHTMTEIERTAADVEKEGMFIGRYVINPLNGKKVPLWIANYVLVEYG
                     TGAIMAVPAHDERDRDFAEKYNLDIIDVITEDNKMINSEEFNGLDASEGFEGIIDKLE
                     KEGRGKRTINYRLRDWLVSRQRYWGCPIPVVYCDECGIVPVKKEDLPVLLPTDVEFTG
                     KGESPLTTSKQFMSTTCPHCGKPARREVDTMDTFVDSSWYFLRYVDSNNENEPFSKEL
                     VNRWHPVDQYIGGVEHAIMHLLYARWFVKAFKSMGMVDFNEPFKNLLTQGMVLMDGSK
                     MSKSKGNTVSPMDIIDEYGADTARLFVLFAAPPERDLDWSEQGVDGCFRFLNRVYRLV
                     DELADVVKKDVEFGELNSQDKDMRYTIHSTLKKVTADLSEKFGFNTAISALMELINDM
                     YKYKELDNINEAVIKEGVQTIVTIIAPFAPHLGEELWTMIGKEGSVFDIDWPKYDEKA
                     LVKDEIEVVVQVNGKVRGKLTVNSNISKDEMEKVALEDEKIKGLVEGKTIVKVVAVPK
                     KLVNIVVK"
     gene            40042..40710
                     /locus_tag="PC512_001377"
     CDS             40042..40710
                     /locus_tag="PC512_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HDF2441137.1"
                     /translation="METVTNNQSGVEIQLSLFEAIKDLLLINPIFLLGIILIGIFLVV
                     IFKKNSDIPKVKTSILSLAMYYYLCLTLSHIVGIPTFGEYIRLSQLGETFFNPNINLI
                     PFSDGFSLSFILNILLFVPLGFLCPLISKTFERLRNTFLIGFGLSLFIETIQLFTLHR
                     ATDIDDLLTNVIGTIIGYFCFKLIAKLRIVKLHSDDDSMEQDYTVCIPIAIIIVALIL
                     GFFS"
     gene            complement(41028..41300)
                     /locus_tag="PC512_001378"
     CDS             complement(41028..41300)
                     /locus_tag="PC512_001378"
                     /inference="COORDINATES: protein motif:HMM:NF012798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDF2441138.1"
                     /translation="MSKHQFKSVSTFFTKKNVSQFYKKNNLKKIRIHDLRYTSATLLL
                     LGGTNMKVVSERLGHTDIKITMNRYSHVLKEMDKEASDNLSELLFK"
     gene            complement(41531..41952)
                     /locus_tag="PC512_001379"
                     /pseudo
     CDS             complement(41531..41952)
                     /locus_tag="PC512_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431042.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(41971..42069)
                     /locus_tag="PC512_001380"
                     /pseudo
     CDS             complement(41971..42069)
                     /locus_tag="PC512_001380"
                     /inference="COORDINATES: protein motif:HMM:NF026008.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Arm DNA-binding domain-containing protein"
     gene            42352..43722
                     /locus_tag="PC512_001381"
     CDS             42352..43722
                     /locus_tag="PC512_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp29"
                     /protein_id="HDF2441139.1"
                     /translation="MKLKKLLSLGLAVSMFAAGPISANALDTIYTIQGKDKYETAALI
                     ADEQNYTTAILINADSTMADGLSASGLAGATNAPIFLTKKNNIPNATLKRVEKAKKVY
                     IIGGESSIDKATETLLKDKGIEAKRLQGSDRIKTSYNVAKEINSINKVNKVILTNAFK
                     GEPDAMSAAPVAVRDKAAIVLTDGKSVPFNTTGVESYVIGGTSSMSDKLVNDTNSTRL
                     GGVDRYDTNKKIVNKFYNGAKEFYIASGTDLVYALVASPMAKNNPIVLVDIGSNKDIL
                     KNAAKVTGIGNLSDKIMLECENTINNISLPSSNKNIICGLKIDFDSKHIIWQDKGSYL
                     ECYDDNLEYYTEKYKDPTVPINIENTSTQNLDVTKLKVYGEANSTLYMGQYAKIKMDF
                     NSFGVLKPGEKCTIYLDIISLDPSRSMTLTFSYVGDKENYKYEQGLASRILFYNPDGE
                     DFFEYK"
     gene            44081..44239
                     /locus_tag="PC512_001382"
     CDS             44081..44239
                     /locus_tag="PC512_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441140.1"
                     /translation="MDNFLQGILASLSASLIVYIASKLFRKRKKPLKAATKSGWEFDL
                     KIRFHKTK"
     repeat_region   44525..44882
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=44525..44553
                     /rpt_unit_seq="gttttatattaactatatggaatgtaaat"
     regulatory      complement(45024..45121)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            45347..45730
                     /locus_tag="PC512_001383"
                     /pseudo
     CDS             45347..45730
                     /locus_tag="PC512_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431032.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
     gene            complement(45919..46914)
                     /locus_tag="PC512_001384"
     CDS             complement(45919..46914)
                     /locus_tag="PC512_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HDF2441141.1"
                     /translation="MSIKKKVAIVFTGGTISMTVDDKVGAAIPTLSGEQILSMVTNID
                     KVADVEVFNFDEIPGPHITPYRMMELKNYVNDLLARKDITGVVITHGTDSLEETAYFL
                     DLTIDNIKPVIVTGAMRSSSELGYDGSSNLSASVCTAVSKDAMGKGVLVVLNNEVLLA
                     SEATKTNTLSLNTFKSLTSGPLGIIDCNELVLTRDIVNRTIIDTDKVESKVALFKAYV
                     GENADFIRFAVDSGYKGIVIEAMGRGNIPPQMLSGVEYAREKGLPVVIVSRCHSGRVF
                     DSYGYFGSGRDLKNLGCIFGGDLPGQKARIKLILALGKTDNLDEIKDFFEKGIYC"
     gene            complement(47035..48663)
                     /gene="aspD"
                     /locus_tag="PC512_001385"
     CDS             complement(47035..48663)
                     /gene="aspD"
                     /locus_tag="PC512_001385"
                     /EC_number="4.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 4-decarboxylase"
                     /protein_id="HDF2441142.1"
                     /translation="MKNHTYKEIKNIYGKISPFEFKDKLIDIAKYTAKENNRELLDAG
                     RGNPNWTCSTAREAFFTFGHFAITETRSNWDLGHLAGMPQKKGIKERFFKFINENIDM
                     PGAYLARDIINFGINELGFDGDEFVHELADGIIGDNYPLPDRMLPHMEKIVHDYLVQE
                     MKYDISGKYGDVEIFAVEGATAAMCYIFDSLMANELLKKGDTIALMTPIFTPYLEIPN
                     LPRYDFKVVNINANEVDEKGAHTWQYTKKELEKLRDKSIKALFVVNPNNPASIAMDET
                     SCNNLIDVIENYNKDLMIISDDVYGTFVEDFSSLMSKLPYNTVGVYSYSKYFGVTGWR
                     LGTFALHKKNVFDKKINDLTGELKKSVDKRYSDMSLNPSSLSFMERVVADSRLVALNH
                     TAGLSTPQQVQMAFFSAFALIDKVDAYKKLNMSICHRRQKLLFEALELPINENKNNAA
                     YYTQFDIEEWAKLNYGEDLFKFISKTASPVDVLYKLANDYSVVLLSGNGFYGPEWSIR
                     ISLANLYDEAYTKIGKAIREILNGYIVEWQKIKK"
BASE COUNT        18697 a         5555 c         8180 g        16383 t
ORIGIN      
        1 ctatatctaa agaaccaagt ggtagatatt atgtatcatt atgctgtact gatgtagata
       61 ttgaagcatt tgaaaatact aataatcaga taggtttaga tttaggaatt aaagaatttt
      121 gtatctcaag ttgtggagaa tttatagaaa atcctaagta tcttaagaag tcattaaaca
      181 agcttgctaa attacaaaga gaattatcga gaaaaacaat cggtagttta aatagaaata
      241 aggcaagatt aaaagttgca agacttcaag aacatatagc taatcaaaga aatgattttc
      301 tacaaaaact atctactaaa ttaataaaag agaatgatat tatttgcata gaagatttac
      361 aagtaaagaa tatgattaga aatagtaaac tatctcgctt aatttcagat gtatcatggt
      421 cagaatttat tcgtcaatta gaatacaagg ctaattggta tggtagacaa attgtaaagg
      481 taggtaaatt ctttgctagt tcacaaatat gtaataaatg tgggtataaa aacgaggaag
      541 ttaaggactt aaatataaga gaatggattt gtcctagttg taatgaaact cacgatagag
      601 atataaatgc aagtataaat atattaaaag aaggattaag actaataacg attcaaaata
      661 aataacatat gtaagaaccg taggaactac ggggatagcc tgtggagaat tagtaagaca
      721 tattttagta tgcaaaattc tatgaagcag gaaccctgtg actttagtca tgggaggttc
      781 agtttatttc aaataatatt ttacgtaatc catctatgtt aattggatta atagcagcat
      841 ttggtcttgt actacagaag aagaaagcat ctgatgttat aaaggggtca ctacttgcag
      901 ctttcggaat tataattatg gagactggaa caggtatgtt agttagttca atagcaccaa
      961 ttaatggagc tttccaaagt ataagtggtg gtgcagtaac aaaaggttta agtgatgtta
     1021 cttttactgc aagttatggt ggaattatag gtttagcaat gtttgcgggt ttagctattc
     1081 acctaatgat agcaagattt actcctatta agacaatctt cttaacaggt cacatgcttt
     1141 attggttccc attcatattt gtagcttcag gagttgaagc tggattaaat ggtggagtat
     1201 taataacttt tgcagcagta ttatcagcac tctattggtc aataatgcct tggttattaa
     1261 gaaaatatgt gtttgatgtt ataggagatg attcttttac attaggtcat ccatctggtt
     1321 gtttagcact tatatcagga tttgttgcta aattagtagg aaataaagaa aaatctacag
     1381 aagatataaa catacctcaa agtttatcat tttttagaga aatatctata agtggtggaa
     1441 tggcagtgtt tttaatgttt atagttgttg ggatagtaat accaggtgcg tttaaagata
     1501 gtaatgagtt tattggaacg tatgcaataa agcaaggtct ttcttttgga gcaggtctta
     1561 taataatgct tcatggggta agaatgctaa taaatcaaat aatgccagca tttcaaggta
     1621 tatctgaaaa agttgtgcca aatgcactac ctgcttttga ctgtccaata ttatttaatt
     1681 ataaaccaaa tgctgtatta ataggattct tagttgctat gctaacatct acagctatga
     1741 ttttaatata taactacttt aatgtattta atttgctact tataccactt gttataactt
     1801 cattctttga gtgtggagca gcagcagtaa taggagaatc acaaggtggt atacgtggag
     1861 ctataatagg tacagctata gctgcaatat ttatggtagt tttagtagga atatctgctg
     1921 taatttactc aggaactatt caaaattgga tactaatatt tggaggtaat gacctttcat
     1981 tatttggtat aatcagtagg tttataggtt cactatttgg aggaatatta tagatatgaa
     2041 atttaaatac atagatgaga taagaagatt aattgatata atagaaaacg aagaaaaagt
     2101 caatatggaa aaagcagtac aaatctttgt tgaagcaata gaaagtaaaa atgctatatt
     2161 ttcatttgga gcttcacatg caggaatatt aacagaagaa ttattctata gagcaggtgg
     2221 ctgtgttctt ataaatccag tatttgcaaa atctctaatg ttagatacag cgcctataac
     2281 tcacacaagt aagatggaaa gattagaagg atatggtaca gctctagctg ataaaactcc
     2341 aattaaaaaa ggagatgtag ttatagttca ttcagtatct ggtagaaatc cagtaagtat
     2401 agagtttgct atgaaagcta aggaaaataa ggcaatagta atatgtataa ctaatttaag
     2461 ttactcaaaa agtgtatctt caagacattc ttcaggaaaa aaactttatg aagtatgcga
     2521 tttagtgata gataatcatg gtcaaaaggg agatgcctgt gtagagatag atggattaaa
     2581 ccaaaaagtt agtccaactt ctactgtaat agcaactact gtgatgaact ctattatagc
     2641 tcaagctact caggaattag ttaataaagg gctaaagaat cctccgattt tctatagtgc
     2701 caatattgat ggtggagatg agttaaataa gaagattttt gatgaatata aaagtgtaat
     2761 tcattatgaa tattaaggtt aaaaaaatat gttaatgaac tttgaagttt atcaacaaag
     2821 aatattaata atatataata aatgctatca tttaaaagct gtaggtaaaa atctacagct
     2881 ttttattatt gtagattaaa aagatgcgta attaaatttt aaattggaga aaataaattg
     2941 gaaggtatca attataaata ttagaaacgt tgtcatagaa aaaaactata ttaaaaaaaa
     3001 gtacatagaa aaaactgatt agacaataaa tacatgcttt gataatattt taaatggaat
     3061 gaaaatgtgt agaattataa tgaaaaaaga aaataaaaat gaaaaaagaa aataaaatgg
     3121 agggaataaa agtgggtatg ttaaaaaaat tatgttcact agctatggta gcaattatga
     3181 ctacaacact tataacaggg tgttcaagtg gaaatggaaa agattcaaaa aaggatggcg
     3241 aaaaagaaaa actagttctt tggatgccac cagtagaaaa taatatgaag gaagtttggg
     3301 accctatttt agataaattt gaggaaaaaa ataactgtga agtagattta cagataattc
     3361 cttgggataa ttattctgaa aaatttgcaa cagctataag tgctggcgaa ggtccagatg
     3421 taggatatat gtatgcagaa atgtatccac agtttataga aagtggagca gtagaagatt
     3481 tgactaacta tgcaactaaa gaggataaag agcaatctat ttatataaaa acatctgaaa
     3541 tgatgggtgg aatgtatggt atgccattcc aagcagcaaa tccaggggta ttatactata
     3601 acaaggatat tttagagaaa ctaggagaaa aacctcctaa aacatgggaa gattttaaaa
     3661 gaatttgtaa aaaagcaacg caagatactg atggtgatgg aaagatagac caatggggat
     3721 tagctcaggg atggggagct aaaacttttg gtaacttaaa ctggaactgg tatccttatt
     3781 tatggcaagc tggtggagat atatttaatg atgatttaaa atcggttaaa tttaatgata
     3841 agagtggttt agaagcagct aatttcttaa aagaattaca agcatatgtg cctgaagatt
     3901 ctttatctaa agatagtaat gaaatgatag aaagcgtatt tggaccaggg aaagcagcat
     3961 ttacaataat gttatcttct gctgcaacaa gtgtatttga tgaatcattc ccggatttaa
     4021 attggggatt tgtaactgga ctagaagata agaaagcagc aacttttgga gcagtagacc
     4081 atttatcttt aatgtcatct gctaaaaata aagaacttgc atacaagtta atacaacata
     4141 tgttaagtgt tgaatcaatg acagaatttc ataaagcaat accaagagca ccaataacaa
     4201 aaggtgaacc atatcaaggt gatgaaagat tcaaagaaat ggtggaaaat gacaaaaatg
     4261 tatatagacc attagtagta ggacctcatg gagttgaaat atatgaatat ttatggaaag
     4321 aacttcaaac tatgatttca ggagataaaa ctccaaaaca agcgttagat gatgctgcaa
     4381 aatattcaaa tgatttatta gcacaataaa agtttaaagc tgtaatatgt tgtaaaggac
     4441 tttacagatt aaaattagca ttgtatttat aaatacaatg ctaatattta tattggagag
     4501 gataaaatgg aaaacttagt tagagagttt gaagaaaatt caaaaagaaa aaaaacaaaa
     4561 ttaaatatta aaccatatat gtatatattg ccattgggaa taattttagt ggcgttttat
     4621 gtgataccaa taataatgtc aatatacttt agttttacaa agtataatat tattagtcca
     4681 gctactttta taggtttaga aaattataaa aaattattta cagatgaaac attaaaagta
     4741 tctattataa atactattaa atttactgtt gttgtagtac cttgccaaac tatattatca
     4801 ttgattttgg ctgtttggat tacaggaaaa ggaaatagta aaatagcttc atttgctaaa
     4861 ggtgctatat ttataccagt attatcatct atggttttga taggtatggt atggagggct
     4921 ttattgaatg gagaaggttc tattatatat caggtattag gtgcctttgg aatagaatca
     4981 tctaaacttt taggagatag taagacagca ttacctacac ttatgtttat atctatgtgg
     5041 aaaaatatag ggtattttat ggtaatttat atttcagcta taatgaattt accaaaacac
     5101 tgctatgaag tagcgaaggt tgatggggct acaaaacttc aagaatttat aaaaataact
     5161 gtacctttat tgaaaccaac tacaataatg gttgtatttt tagggtcgat atggtcatta
     5221 caagtatttg acttaattta tactgtgaca ggtggaggtc caggtatatc tactatgagt
     5281 atagttatgc atgcatttaa cttaaacttt aaaaacttta attctggata tgcaatgact
     5341 gtagcaaacg tattattttt gttaatagca gtagtttcga ttttacaaaa taagcttgta
     5401 agacgagaca attcagattt ttagaaaggt aggtataata tgaaaacagc aagaagatta
     5461 ttaagtgatg gtttgctttt atttatagcg tgtgcaagtt tggtaccttt tatatacatg
     5521 ttgataatat cattgaagat aacatataac tcatatagtt tggatatatc tttttcaaca
     5581 gtaacccttc aaaactatat agatattttt actaaaaaag gatttgcaca atattttttt
     5641 aatacagcaa tagtatcttt ttcaggtgta ttattaaatt tagtatttag tacattagca
     5701 ggatattctt ttgcgaagat ggattttaaa ggtagtgata agttattttt atttatgata
     5761 atgactttaa ttataccttc ccaagttaca atgataccac tatatataat aatgaaacac
     5821 ttaggatgga taaatagtta tcttgcactt attatgccaa taccaactgc atttggcgta
     5881 tttataatga gacaagctat tttaggagta ccaaaagagt tattagaatc agcaaagata
     5941 gatggttgtt cggattttag aattttaata caaatagtgt tgcctttaat taaaccagca
     6001 ttaattacac tagcaatatt tacttttatg ggagcatgga acgagtttat gtggcctctt
     6061 atagctacaa ctaaagatac aatgagaaca ttaacagttg gattatctac tcttaagaca
     6121 ttccagataa ctaattatgg acagatgatg gcaggggcta caataacatt tttacctcca
     6181 tttattttct atttgatttt acagagtaaa tttgttgaag gtgtgtcttt gtctggtata
     6241 aaaggttaaa tagtctaatt taataatata taaagaaact tatataaata tggaggaatt
     6301 taaactatgg aaatttcata tgtactgaaa gattgcacat tcaaacacaa taaatactca
     6361 gttgtagaag ctgaaacttg gaaagataag gatttggata ttgtagtagc taaaggtgaa
     6421 aaatttgcat ttcaaattat gttaaaagca acagaagaat ttaattgtac aattgataaa
     6481 agtagtgcta tatcatggaa aggcctggga aatagagtaa ggttagcatt aaatatgcct
     6541 aatagtttag aaaataattt tagtataaat atattaggat atgttcaaga tgatacaaag
     6601 gcatttgtga atgatgctat tttaagggat aaagatgtgt tagtagagca atatttgcct
     6661 caaacatttt ggattgaagg tcaagtacca gaagattttg aagaaaataa ccttgatata
     6721 ggtattgata tatttaaaag ctttggatat gaagacgaag aaaaagtttg tacaattgat
     6781 gttcctgtaa aagtaagaaa tgttgtgcta aagcctttag atgaaagcaa gttcttttta
     6841 gatttatggc aacatccaag ctgtttagct agaatgtata aagttgagtt atggtctgat
     6901 atacattttg aaatagtcga taactattta aaagaattag catctttagg agaaaaagtt
     6961 gcaacagtta tagtttcaga ttatccatgg gcagggcaaa gttgttataa agtttataaa
     7021 aatccatcaa acttatatga atataacatg gtaagtgtat caaaaggatt ggatggaaag
     7081 attaaatgta actttgagag tatggatagg tatataagca tagctgataa gtataaaatg
     7141 gctaaggaga tagatttatt tggtctatta ggtaattggt gtgctggtga gtttggaaat
     7201 cctgtagaag gttataagga ccctataaga gtaagatatt ttgatgaaaa ggataaagta
     7261 tttaaattta taaacaatac aaatgattta aaagaatata taggattagt attaaatcat
     7321 ttaatagagt gtggattatg ggacagagta aggattatag ctgatgaacc aaataatcca
     7381 gaagtagtca aagagtgtat agaatttata aattctactg taagcactca tcaagttaaa
     7441 tataaatcag caactcacga ccaaaacttt ttagacagag ctaaagatga aattgatgat
     7501 atgtcaataa atttaaaact tactatacaa aattataaag atatagaaag tcttaagaaa
     7561 aaaatcaatg acaagggtgg gatattgact tggtttgtat gctgttttcc agagaaacca
     7621 aatagttttt taagttctcc ttttgtagaa aatagaataa taggatggta tacttattac
     7681 tttggtcttg atggattttt aagatgggac tataatttat ggacagaaga cccttggaaa
     7741 gattcaagtt acaaattccc tatttggaaa gctggagata tgttctttgt ttatcctgga
     7801 aaagatttaa agccagttag aagtgtcaga atggagaatt taagatttgg aatacaggac
     7861 tttgagttat ttacaatgtt agaaaaagaa aagggaagag agtatataga agttgagctt
     7921 atgcaagaat tattaaataa aaaagaaaat gctgaaatta aaggttttgg tgacatagaa
     7981 ctaggatatt cacttgataa ttggggatat gataaagtta aaaaatatgt attagagttg
     8041 ttagacagag tataaaaaat ataagagtgt ctcaaaatga actttttagt tcatgaggca
     8101 ctctttttgt atgaaatcaa tatagtttca ttgtttcaac aatgaaaaat aggattattt
     8161 ctattctaag acagcccttt agttttttag ttgtattcaa tgttttaaaa ctaactataa
     8221 acgctataaa gtttataaat gacaataatt atatataaca tgatgtactt taatttgcta
     8281 taatagggat tgaataatat tatatggaag ataacattgt ttggggggat taatataaaa
     8341 agaataggta ttattataat gtttttttta agtatatctt ttattggatt ttatcttgta
     8401 ataagagata acagtgatac agttaagatg caacgaggga taaatatagg taatgcacta
     8461 gaatcaccta aggattttcc gtgggatgta aaaatgtcaa ataagttttt tgatgatata
     8521 aaagatgcag gttttgacac agtacgtata ccagtaaggt tttctgatta tacgtcagat
     8581 tctgataatt ttaaaattga tgaagaattt tttaaaaaga ttgataaata tgtagattat
     8641 gcattggata aagacttaat agttgtgttg gatttacacc attttgaaga aattatgaaa
     8701 gaaccaagag ttcataaaga aaagttttta aaaatatggc aacagatagc taataggtat
     8761 caaaaatatg ataaaaaatt ggtatttgaa ttattaaatg aacctaaaga aaatttatat
     8821 tcacagttac taaacgaata cattgaagaa gcaataaaga taattagaaa aactaaccct
     8881 aaaagaacta ttatagtagg accatataat ttctatcaaa ttgattattt gaatgaatta
     8941 aatattccta aagattctaa tatagtagtt tcctttcact attacgagcc aaatgatttt
     9001 gcatttcaag gaaatatata tcataaggga tttgagcact taagcaatat tacttgggaa
     9061 ggaacaaacg aacaaatgga ttatttaaaa aaaaggtttg atactgtgga aaattgggca
     9121 aataaaaata aggtaaaaat cttcttgggt gaatttggaa taacaaaaga ggcaccagaa
     9181 gcttcaagaa gagcatggat aaaagctgta agagaagaag ctgaaaaacg aaacttttca
     9241 tgggcttatt gggagcttgc atctggattt ggtatataca atcaaattga agggacttgg
     9301 gatagagata tattaagtgc attaatagaa aagaggtgat tttatgaaga aaaattcaaa
     9361 aaagatactt ataactttaa ctattattac taatgtcata tatatattgt ggagaatttt
     9421 ttacacagta cctaaagaag aagggaagtt tgccttaata tgtgccataa tacttctttt
     9481 tgtagagata atgggcatga tggaaatgtt tgtgcattat tatggtatgt caaatattga
     9541 gtaccctgaa aaaccaatca taagtgaaga actttatcca catgtagatg tattcattgc
     9601 aacatataat gaatctgttg atttggtgag aaaaactgta aatgggtgta ttcatatgca
     9661 gtatccagat aagaaaaagg tacatatata catatgtgat gatggaaatc gtgaagaaat
     9721 gtgtattcta gcagaaaaaa tgggtgtaaa ttacataact agaactgaaa gagaaggagc
     9781 aaaagctgga aatttaaata atgcaatgca acatacaaat tcccctttga ttgctacatt
     9841 tgatgcagat atgataccaa tgcatgactt tttaattgct acagtaccat actttttgaa
     9901 aaatgagcaa gctaaaaaag atggagaaaa agaggagtat gaaaaggttg gttttgtgca
     9961 aactccacag agtttttata atccagactt gtttcaattt aatctgcact ctgaaggaag
    10021 gattccaaat gagcaagatt atttttacag agacattcaa ttggctagaa ataggacaaa
    10081 ttctgtaatt tatggtggta gtaatacagt tatttcaagg gaagcacttg aagaagttga
    10141 tggattttat acttattcta ttacagaaga ttttgcaaca ggtatcttaa ttcaaagtaa
    10201 ggggtataga tgttatgcta ttccagaagt acatgcatca ggtttatctc ctacagattt
    10261 aaaaagtctt attaagcaac gtgaaagatg ggcacgtgga tgtatacaaa ctggtagacg
    10321 tctaaatatt ttgtttagga gaggtttagg tttttggcag aaaataagtt atatttcttc
    10381 aattacttat tggtatgcaa gtataaaacg ctttgtatat ataatggcac ctattttatt
    10441 ttctgtgttt aatgtgattg tagtaaaatg tacgttactt caagtattgg tattttggtt
    10501 gccaatgtat attttaagta gtttatctct taaaatattt tctcaaaata taagaaatac
    10561 tagatggacc aatatatatg aaactataat gtttcagtct ttaatgccag cagtaatact
    10621 tgaaacgttt gcaatatcta aaaataaatt ttcagtaaca aataagagta aattagaaga
    10681 aaatagaatg tataagtttt tacagggaat accttatttt atttacatgg tcttatctat
    10741 cataggaatt ttaaaaatgt ttgtagcaat atttaaaatg agttcaatga catattcagt
    10801 tgtattattt tggttgattg gaaacctttt taaccttgtt atggctacat tatttatatc
    10861 agggagacag cagttaagaa agtctgagcg ttatattgct gaaattgatt ttaagttaaa
    10921 gcaaaattct tatgttcttt cttcaaaaac aattgatata tcagaaaatg ggtttgcatt
    10981 tttgctagaa aatccagaat atatttcccc agaagaagag tttgaggtag agtttagaga
    11041 aaaatctgga aatgaaatgt atatagctaa tatgaaagca aagattgtta atgttgtgga
    11101 agtaaattca aagtggaaat atgcagctta tattacacat attgaagata gtgaaataga
    11161 taattggatg tgtattgttc acgatagaat acctacttta ccaatgacaa tatctaatca
    11221 actaggtttc tttgatgatt tgcaaattaa tgtaaaaaaa cgtattgaaa aaactagaac
    11281 attatcacga agaagtccaa gaatcaatat gaattttcag atggatataa aaaatacagg
    11341 taaattaaga atagtgaatt ttaattatca atatgtatta ttaaattttg agaataaaag
    11401 tatttatcct aaagaaatag cattggaaat taatgaaaat attgtgttag aatgtgattt
    11461 gtgtgagggt aaaattgatg aaagaggtat cttatataaa gtaaataaca ttgacagcat
    11521 aatgcaaaat ttctttttaa gagatgaaat gatggattgg atattacaaa ataagaaaat
    11581 tcttgattca aagcctagtg aaaagaagga aaaaagtata gatgagtttg aacccatgga
    11641 atatatttag gagagatgaa atgaagactt taaaagtgtt tttttgttct acaaaatatc
    11701 ttattttggt gtttattttt tttataaata ctacttttat aagttcagca acaagtgata
    11761 aaattttaga tttatccttt aaaaagatag agactgactt aagttctaag attacatatg
    11821 aggatacagg tgtaaaaata gaaacggata gttctaaaag cgataaggaa cgttatttat
    11881 atatttacca aaatataaaa gaaaattgga gcatgtataa taatttttat attgaaattc
    11941 aaaataaaaa taaaagttct cagagaataa atttaagcat acaaagtaaa aatatgcttg
    12001 aatttagatt aaaagaaggt agtgaagtat ttttagaagg taaaaatata atatattcag
    12061 ataaaataaa agaaggatgc atagaagtac caggtgaatt tgaaggcaaa atttatgtga
    12121 actttaatag ccttataaat gaggaaagta atgttgtgct ggactcaaat atgctttcaa
    12181 acattgttag ttggggaatt acgtttattc catctgatga agaacataat attgttatta
    12241 taaaaaagat atctttattg tctgaagaga aattaagatt tttaaataat attaaaataa
    12301 ttggcgatga agaagtacaa ataccagtat tgggtcaaag tataagtcag tatgaggtat
    12361 taggtcttaa aagtgattct aaaattaagt actctcttat gggaaaacaa gataatgtga
    12421 gtatatctca aaacggtaaa ttaacattaa gtaataaagc caaacctgga caaattattt
    12481 tacaagttaa tgttgatgat aagtttaaaa ttggaaagaa aataacatta actgaatctt
    12541 ggagtattaa taaaaaagat aaggatggtg ttccatatac attagtatct cctgagcaat
    12601 caccaacagt acaagatatg aaaaaaataa attttatgaa taatatcata acgtttgttc
    12661 gaattttatt tgtatctcta gtaataatat gctttggaat atatttatat tggaaaaaat
    12721 gttcaaaaac taagtaaaga gaggaggtta gattgtgtta ttttcaagtt taattttttt
    12781 attttatttt ttacctataa ctttggtttt atattatgta tttaggttta accgaacgat
    12841 acagaacatg atattgcttg ctgttagttt atttttttat gcttggggag agccaaaatt
    12901 tgttgttatc atgatagttt ccataataat gaactatata tttggtttac tggtagatag
    12961 atatagggaa agtaaaataa aagtaaaagt ttttttagtt ttgatgtgtg catacaatat
    13021 aggtgtttta tttatattta aatatctagc ttttgcgcta agaaatatta gtgaacttat
    13081 tagtactgaa ttgactatac ctaatattat tttacctata ggaatttcat tttttacatt
    13141 tcaaggaatg tcttatgtta tagatgtata tcgtagacat ggagaagtcc aaaagaatcc
    13201 tttttatgtg ggactgtata tagcattttt cccacaatta atagcaggtc ctatagttag
    13261 atatgagagt gtggcagaac aaattctcaa tagaaaagaa acttggaata aattttctat
    13321 tggtacttgc aggttcataa caggtctagg taaaaaagta ttaatttcaa ataacatggc
    13381 tatagtagca gactatattt acactatgaa tagtcaagga gaaatagctg catcacttgc
    13441 atggcttggt tcaatagcct atactctgca aatattcttt gatttttctg cttattcaga
    13501 tatggctata ggcttaggtc ttatgtttgg ttttaaattt gaagagaact ttaattatcc
    13561 atatatatca aaatcaatta gtgagttttg gagaagatgg cacatttctt tgggaatgtg
    13621 gtttaagagc tatatatact ttccgcttgg aggttctaga gtagcaaata aagatattat
    13681 gattagaaat atgtttatag tgtggttatt cactggaata tggcatggag cagaatggac
    13741 atttgtaatt tgggggattt taaactttgt tttcctaatt atagagcgat ttataatgtt
    13801 tgaaaagatt gaaaatcaca attttataaa acatatttat gctttattag tagttaattt
    13861 tggatgggta ttgtttaggt cacctaattt aaaagaagca tataattatt ttaaagctat
    13921 gtttggaggc aatggagcta tatggagtga ttatacatat atgtttttaa aagaatactg
    13981 ggttttcttt atatttgcat ttatttttag tgtacctatt gcaaagaaaa tcaataagtt
    14041 tgttgttgaa caagctaaat atagtatgat atttaacgta ttttatccaa tctcagctat
    14101 tttattgttt tttatttctg tgacatattt agtaactgga agctataatc catttattta
    14161 ttttaatttt tagttgggag gaaaagtatg aatagatttt ttaaagtaag attaataact
    14221 gcaattatgt tcttaattat tttattcgct ttctctatct ttaatgtttg ttattctgga
    14281 aaagatacga tacaggaaat aaaaaattca atagctgaaa aaagtagttt aaaagataca
    14341 atatcatcta ttgataatac agtgaatgac aaagtaatat acaaaaatac gttcattgaa
    14401 acttatggct atttacaaaa attaatgggt aaaaatgagt tttcaaaatt tagtgttgta
    14461 aaagatactt ctggaaagat gcattataca tattttgcta aagctccaaa tccagttggt
    14521 gtgatagcag atagggtaag aaaattttct gatgaaatgg aaaagcaaaa cactaaattg
    14581 gtttacctaa tgactccaga taagtatata aaaggagtga caaaatttcc aaaaggaata
    14641 ccttattctt atagtaatga gacagcagat aattttttaa atcaactaaa aaagtataat
    14701 gtggactata ttgattttag agaaaatatt ttaaagagtg gtattccaaa agatgattta
    14761 ttttttaaaa cagaccatca ctggaaagta gaaacttctt tttgggcatt tggagaatta
    14821 gttgagcaac ttaataaaaa atacaatatg aatttagatg aaaatcatta ttatagagat
    14881 aaggacaatt ataattcaat tgtatatcct aagtcatttc ttggttctat gggaagaaag
    14941 actggtatct tatatggtgg tatagatgat tttacattaa tttatcctaa atttaagact
    15001 aattatactt attatacaga ttctaaatct caaaaatttg aattaaaagg aaggtttgaa
    15061 gagagtttaa tattatcata tccttttaat gcagaccttg atttaatgga tggtcaatca
    15121 gataagtatt ttacatattt attggggaac agaccattag ttaaaataaa aaatatagaa
    15181 aatccagatg gattaaaagt gctgtttgtt aaagattctc taattgtacc aacagcagca
    15241 tttttttcct ctgtttgttc atctatagat atgatagacc ctagatatta tgatggagat
    15301 atactagaat atgcaaaatc ccatgactat gactttgttt ttatatctgt atatccccaa
    15361 aatcttacaa aagaattttt tccgttttgt gagtaaattt ctaaaaaagt tttctgataa
    15421 aataaatggc taactggtaa aaagttagcc atttattttg agtgttattc taagaaatat
    15481 tttttttact aaatacttct ttatctattt ttccaagtga ttttcctaca gtaattgatg
    15541 ataccatagc accattaaca tttatcatag tacgtcccat atctagtata gggtctattg
    15601 caagtatacc accaactaat ggaaaataag aaccaagacc aactccagag ataacaactg
    15661 aaacggccat tgtagcagtt cctggaagac cagctattcc aaacgaacta attgttataa
    15721 caattaacaa cataacataa aagctcatat ccatgtttac tccagccata ttggcaagtg
    15781 ttacagccat taaagcagga tatatacctg cacaaccatt catacccata tttgcaccta
    15841 aacttgctgt aaagcttgat acaccctcat caactccgtg attttgtact agactttcta
    15901 tcgttacagg caatgttcct aaactagaac gtgaagtaaa tgccagaagt aaagcttcag
    15961 ttgaattttt tatataagta atgggattta gaccatttaa agttataaaa attaaatgta
    16021 taataaataa tattgcaact gatatataaa gagctaatat aaactgtaaa acagatacta
    16081 ttgaactaat accttgtgaa gttattgtat ttgcaagcag agcaaccaca gcataaggca
    16141 taaatttaat aacagtcata gacacactta caattatttt gtaagatgct tctataaaat
    16201 ctataaatgg ttttattgtc tcaaaatgtt ttttacttaa tctctttatt gaggtagcta
    16261 taaatgtagc aaatattatt gtagctacaa tatttccatt tgccatagcc attacaggat
    16321 tagatggtag taatcctctt aaagtatcca caagagagtt tatttcttta agttcttgat
    16381 tttcaactaa agtaggcata ttagctccta cacctaactt cattatattt gcaacgataa
    16441 ttccaacaat tgcagctata gcagtagtag caagaagcat acctaaagat ttaaatgtca
    16501 gagttccaag attgttatct ttcatattta taattacttt tataatggat aagaaaacta
    16561 aaggtactac taacattttt aataagtcca taaatccaga accaaatagg ctataccact
    16621 tacttacttc ttgtagccaa gtgacttgag ttgtatcatt aggaaaacca gcaaaagctt
    16681 gtattatgat tcccaatatg agtcctagta ctgtagcata tattgttctc aatgaaaatt
    16741 ttattttttt cttttcaaat tgtctaacaa taaagaacgt acctagaagt aatattatga
    16801 aaaaaattgt tttaaaatct gtaatcataa gaaattgtga taaaaatgaa ctttccaata
    16861 tttttctcct tttatttaaa aataaatttt tctaagttta aatgatatca atatattaaa
    16921 aaaatgtcaa tattatatca caatttactt aaatagagta aaacaagttg attttgaaaa
    16981 atgtgattaa gtacagaaaa atagggtata ataaatgttt aaagaatttg aattgtggta
    17041 agaaaataaa aaatagcttt tataagattt gatttcaaat taaaatatgt taaataaata
    17101 actaaaaatt attataaaaa atgttttcat agaatatata tcaaatgaaa agcttaaaat
    17161 aagtgaagaa attaactaga catcaaagga gagataaaat gagagtaata ataattggtg
    17221 gtgttgcagc tggtatgagt gctgcagcaa aattaaaaag aataaaacct gagtatgaag
    17281 ttgttgttta tgaaaaaact gaaatagtat cttttggtgc ttgtggatta ccatactttg
    17341 ttggtggatt ttttaatgat gctgatgaat tattagcaag aacaccagag aaacttagag
    17401 aagctggaat tgatttaaat atatttagag aagtcgttga ggttgatagt gaatctaaga
    17461 aaataaaagt aaaaaacata aaaacagatg aaatatatga agattactat gataaattga
    17521 tgatagcaac tggagcaaga agtattatgc ctcctataaa aaacataaaa ttgaagaatg
    17581 tttctacatt aaaaagttta tatgatggag aatatctaaa aaaactttta agtaatgaag
    17641 ataataaaag agtgacaata ataggagctg gttttatagg gttagaagca gttgaggcat
    17701 gtaagaaatt aggtaaagat gtagatgtaa ttcagttaga agatagaata ttgccacaag
    17761 tatttgataa ggaaatgacg gatgtattag aagaagaaat aaatagacat aatgttaatt
    17821 tgcacttaga tgaaatggtt gtagaacttt gtggagaaga taaagtagaa aaagttataa
    17881 caaacaaagg ggaaatagat acagatgtag taataattgc tactggcgtg agacctaata
    17941 ccgagttttt gtcaaatact aatataaaaa tgctaaaaaa tggagctata gtagttgatg
    18001 agtatggaag aacttctgta gaagatatat actctgctgg agattgtgca actataaaga
    18061 atatagtaag taatgaaaat gtatatgttc ctttagctac tggagctaat aaattgggta
    18121 ggatagtagg agaaaaccta gcaggaagag aagtatctta tcaaggttca ctatcttcaa
    18181 gctgtataaa aattatggat atggaggcag catcaactgg aattacagaa aagcaagcta
    18241 aagatttagg cataaatgtc aaatctaaat ttatttctga ttataatcaa actcattatt
    18301 atccaggaag aaataaaata tatgtaaagc ttatttatga tgcagataca aaagttattt
    18361 taggcggaca agtggctggg tttaaggatg ctgtccaaag agcaaatgta ttggcagctg
    18421 ctatctttgg aaaaatgacc acaaatcaac ttggaatgtt agatttatgt tatgctccac
    18481 catttgcaag aacatgggat gttttaaatg tagctggaaa tgtatctaaa taatatttag
    18541 attatagcta atatagttga caagcaatta agggaatgaa tttacctaaa ctatttttat
    18601 catggtaaaa ttcattccta aatttttatt ccaaattttt attccaaatt tttagaaata
    18661 aggattccat taaattattc atcaaaattt aaacgcaagc ttaatctatc ttctccaagg
    18721 atagtatttt caaaaacatt agtagcattt tctaaataca tactaggtat gtctaaagaa
    18781 ggactaaaat gagtcagtaa aagttgtttg acatttccaa gttttgcaag attagcagct
    18841 tctctaaaag tcatatgttt gtttctaaca gcttttgata tatctaaatc atcaccatac
    18901 atggcttcac atataaataa atcactatct tttatgaaat ctggtattga ttctataggt
    18961 cttgtatcgg ttgtaagact tatcttaact ccctttctca attctcctaa gaccatatct
    19021 ggagtgtatt gttttgaatc taaaactata ttttgacctt cttggagttt gttccataat
    19081 attttaggaa cttcgttttt agttgcctta tctatatcaa atttagggtt tcttctaaaa
    19141 ttaaaactgt atcctaaaca ctctatagag tgttctaaac tgattgttga aatttctaaa
    19201 tttcttaaaa ctttattatc taaagaaaaa ttgccttgag ggttttctat aatttttaaa
    19261 gtgtatggta catattctac taaatttctc atagaacgta tacaatcgac tattccaact
    19321 ggaccaacta tagttaaatc acttgtacga ccactatttc caattgttga taaaagtcct
    19381 aaaagtccaa atatatggtc accatgtaaa tgggttatac aaatcaagtc tatatcttta
    19441 aagccacatt tttttagctt catagatacc tgagtacctt caccacagtc aattagtatt
    19501 tttctacctt tatagtttat aaatacagag gatagaaatc tgtttggcat aggtacattt
    19561 ccaccacatc caagtaaagt taaatctatc attttttccc ctttctaaaa ttaacacaaa
    19621 tctgttgttt gtttttatta tgatatccta ttataattat tttaacatta aatataacaa
    19681 taaatgtgta tttgagtcaa gaaatattgt caaataaagt ttttatatag aaatgtataa
    19741 aaatttggaa aacaaaaagt gaaaattata tttaggagca tttaaaggag gaaaatttaa
    19801 tgaaagtatt aaagaaaatt actattttgt cattaattac attaacctta gttggttgta
    19861 gtaacggaga agataaaaaa gtggttgaag gttctaagaa aattcaaaat tctaaaaaag
    19921 atgaacagcc tataatagta cataaagatg caaatatatt gaaagatagg tatgagccac
    19981 caaaaggatt taaaagagtt gatgtagaaa aaggtagttt tgaatcattt cttaggaata
    20041 ctaagctaaa aaattatgga gagaaagtaa agtattatga tggaagaact aaggaatcaa
    20101 aaggtattta tgatagtgta tttgatgttg atattggcaa tagagatttg catcaatgtg
    20161 cagatgcaat tatgcttatg agagcagaat acttgtatca gaataaacta tatgatgaaa
    20221 taagttttga ttttgttgat ggttttaagg cgaagtattc aaaatgggca caaggatata
    20281 gaatttcagt aaaagatagt ggttcaagct ggtataaagc aactgaatat tcaacatctt
    20341 atgagagttt tagaaagttt atggatatag tgtttgcata ttcaggaacg ttatctcttg
    20401 aaaaagaatt ggagcctgta aaagttgagg atatgaaaat aggagatgtg tttatagttg
    20461 gtggaagtcc aggacatgca agtataatta tggatatggc agaaaatgaa aagactggtg
    20521 aaaaggtatt tatgatagcc caaagctata tgcctgcaca acaaacgcaa cttcttatta
    20581 atcgtaaaaa tccaaatttg agtccttggt atagtttaga ttttgaaggt gatttgacaa
    20641 tacctcaatg gacttttaaa agagaccagt tgaaaagatt ttaaaataat aattttatat
    20701 aataaaagaa aaatatagat gtgaaaaaat gtaattagat taaaactaat tggatatgga
    20761 caaaattaaa ttgatagata aatattaaaa attacactaa ttaatcttac tatagtttaa
    20821 tatttatcta aaaagtttta tgtaaaatat aaattttata ttaaagctaa aactaatttg
    20881 aggaggctaa tttatattga agattagaag gtatttaatt ttggtaatta taattctaat
    20941 tacaacaagt cagagtttta tttcttatgg gctagagcga tttgaagaaa taaccatttt
    21001 tcacactaat gatatacatg gaagatatgc tgaaggtgat gaccatatac aaataggaaa
    21061 tctagccaca ttgaaaaaag aaactccaaa ctcaatttta gtagatgcag gagattgttt
    21121 gcatggactt ccaatagtaa atatggatag agggaaaagt gcaattgaat taattaaatg
    21181 tgctggatat gactatatta ctcctggaaa tcatgacttt aattatggaa aagatagact
    21241 gtttgagtta tctaaaagtg ctaatttagg agagaatact ttaaaatttt tatcatcaaa
    21301 tatttttgaa aatggaaaaa aagtttttga tagtaatgat ataaaagaaa tagatggaat
    21361 aaaaatagga ttttttggac tctcaaccca ggaaacaaag agcaaaactg gatttaaaaa
    21421 tgtggaagga ttagagttta aaaatcctat agaaagtgca acagaacaag taaatgaatt
    21481 aaaaggaaag ggtgccaatg taatagttgc aatatgtcat attggtacaa atagtttaag
    21541 taagccaaat agtatagata tagcaaatga ggttcaagga attgatttga ttattgatgg
    21601 acacagccac actaagtttg aaaatggtaa acaagtgggt gatacattga ttgtaagtgc
    21661 aggacaatat ttagaaaata ttggcgagat aaaactaact ttggatacta atgatgtaga
    21721 aaatataaaa atagaaaata aatcagttag attaattgga aaagaagaag cattaaagta
    21781 taagcttgac tccgctgtaa gtaaaaaggt tgatgaaata aaagaacaac aagaaaaaat
    21841 attagataaa gttatagggg taactacaaa tactctagat ggttcatatg aaaatgtaag
    21901 gacaaaagaa actaatttgg gtaatttaat aagtgacatt ttactagata aaactaaggc
    21961 tgatatttct ttatttaatg gagggaatat tcgagatacg atagaaaaag gcaatataac
    22021 aagaagagat attgtagatg tatttccttt tagcaatact atagttacca aagaacttac
    22081 aggagcacag attaaagatg tattggagca tggagtaaaa ctttatccag aaaaaagttc
    22141 agcctttttg caagtgggag gaatttcata ttactttaat cctaaacaaa aagaaggcga
    22201 aaaaataaca aatattcaaa aagaaggaaa gccattagat ttaaataaaa agtatgtagt
    22261 tgcaacgaat gattatatag catcaggtgg agatgaattt ccttgttttt caaaagagcc
    22321 agtactaaag gaatttggaa atttagagag tgcagtcatt gaatatatag agtacaaaaa
    22381 agaaatatca aaaaatgtag atggaagaat tggtattaaa tctaaagatg agttaataag
    22441 caagaatcat gagagtgatt tgatattaag tgaaaatgaa aaaaatatca atgataatga
    22501 agagaatcta tctaataata taaaaagctc tgatagtgat aaaaataaaa gcttagataa
    22561 aacaagtgct agagaaagtt ctaatctagg aatatctaaa agagaagcta aagaaaaatc
    22621 tcctaaaaca ggagatttag gtttttcaaa tagtataatt atatttatag tttcaagtac
    22681 attgatatgt ttattgaatt ttaatcaaaa agagttaaag gataaaaagt caaaataaaa
    22741 attaatgagc aaaaattagt agatagtaat ttaattttag ataatagtaa acagcaaagg
    22801 aaattagtta tataaatact aatttccttt gttttatgtt ttaacatgat tacttttaaa
    22861 taaaattgta ttttatgaaa aataattaca ctaaatggca tagtattatg gggattttta
    22921 gtttttattc aagtaaatga aatcatatta acaacttctg atatatttac aaattgataa
    22981 aaaaatgatt ttattagtat gatataattt agctagtata tatgatgatg gaggatatag
    23041 ggatgaataa tatattactt ttggaagatg acaaatcttt aaatagagga attagtttta
    23101 aattaaaaaa agaaggatac aatgttttta gtgcatttgg tatagaagaa gcaaaaaata
    23161 ttttcgcaaa agaagagata tgcttaatta tttccgatat aggtctacct gatggtagtg
    23221 gttttgactt ttgtgaggag attagaaaga aaagtgatgt ttacataata atgttgacag
    23281 ctcttgatga agaggtggat attgtcacag gatatgattt aggtgcagat gattatatca
    23341 caaagccttt tagcttgatg gtattaatat caaaagtgaa tgcgcttatg aaaagagtaa
    23401 atacagtaaa aaattatact ctattagttt gtgatgattt attcttttat tatatagaaa
    23461 ataaattaat tataagaaca gatgataagg aagaagagat aattttaagt aagacagaga
    23521 caaaactatt aaaatatttg atggaaaatt ctatgcagac attgactaaa gagcaactgt
    23581 tagaatcttt atgggatagt agtggtaatt ttgtagatga taatacgatt gcagtaaata
    23641 taagaagact tagacaaaag gttgaaaaaa atccatctga acctaaatat ataaaaacag
    23701 taagaggggt tggatatatg tggggagaaa ggagtataaa aaaatgctaa aaaatatgaa
    23761 cctcaaagat ggtttaagtg tgaaagatga ttatataatg agaagagtta ttgtatattc
    23821 tgttttatct gtactaatag taacccttgt atttatactt tttgaatata gcagattaca
    23881 taaattgtat gaacatcaaa taaaaaacac tcaaaatatt gctggaatat tgattgaaaa
    23941 atatcctaat gatgaaatag atatagtaaa ttctatttat aattctgatt atagtaaggt
    24001 gtctactgga gaaaaggcat ttaagaaatt tggctatgga ttggaaaata aaatgtcaaa
    24061 tgataaaaat tttagcttat acttaaaatc tttttttaag gaatcatttt ttattttttt
    24121 aatgatgttt atagtagtta taggtataat atattatttt ataagataca taaataaaag
    24181 attgagtaaa atttatttta tagtagataa gatgtcacaa gaaaactact tgaaggacac
    24241 tactgagtca gaagaaactg gttatctagt agaatataat gaatacttta aagaaggcat
    24301 atttagtaag ataaataact gtctatatga gcttaataga agtttaaaga taaagtttat
    24361 taaattagaa aaagaaaaag aaagtgtaaa atcattagta acagatattt cccatcaatt
    24421 aaaaactcct ttagcatcct taaaattata caatacatta cttatagaag aagaattaga
    24481 agaagatgaa gccaacgagt tcttattaac caataaggct tctataaata aattagaaaa
    24541 tttaataaat tctttagtga acatatcaag gttagaaatt agcatgataa acataaaaaa
    24601 agaagataat gatataaaaa atactattct aaatgcagta aaaagtgtta cccctaaggc
    24661 taagagcaaa agtataacat taaatttaaa tgaatttaac agtagaatta taccacatga
    24721 taaaaagtgg actgaggaga gtatttttaa tgtattagac aatgctgtaa agtatacaca
    24781 ggtaaatgga gaaataaata tatctgtaga agaaactgct aatttcttta aaattataat
    24841 agaggataat ggcataggga ttgaaaaaaa tgagtttaat aatatattta aacgttttta
    24901 tagaggttct gctgatgaaa ttgaatctgt agaaggtagt ggggtaggat tgtatttaag
    24961 tagaaagatt ttagaagaac aaggtggaaa tattatagtt tcttcaaaag taggaatagg
    25021 gagcaagttt tctttgtttc ttacaactat gtaatattaa atgaaaggaa aatgtaagcc
    25081 tctacattta ttatataagt ataaacagct ccagaaataa aaaattaata aaatatggag
    25141 taatataact tagaatgaga ggataatttt atgaaaatac tatatactga aaatttatca
    25201 aagcattatg gaaaaggaga aagcttagta agagctttgg acaatgttga cttagaaata
    25261 aatgaaggtg aatttgttgc aataatagga aaatcaggtt ctggaaaaag tacacttttg
    25321 catatgattg gaggtcttga tatacctaca tctgggaagg tgtatataga taataaaaat
    25381 atatttacat taaaagaaga agaacttgct gtatttagaa gaagaaaaat agggtttata
    25441 tttcaaagct ataatttaat tccatctctt aatgtatggg aaaatgtagt gttgccaatc
    25501 ggtttagatg gtagagaagt agatgaatct tttataaaag aacttttaaa atcattagga
    25561 cttgaaaata aacacgacgt tttaccaaat acattatcag gtggtcaaca acaaagggtg
    25621 gcaatagcaa gagcattagc tacaagacca gctataatac ttgctgatga accaactgga
    25681 aacctagatt ctaaaacgtc tgatgaggtt atgagtatat taaaatctat gtctaagaag
    25741 tacagtcaaa ctctagttat gataactcat gatgacagta tagcccaaat ggctgataga
    25801 gttatattca tagaagatgg cagggtgtca aaggttggtg ataaaaatga ttaatactac
    25861 taaaatagca aaaagtaatt taaagcaaaa taaatcaaaa agtattctaa taataattac
    25921 tataatactt tcaaccttaa tgctttcttc tattggaatt tatattgttg atgcaggagc
    25981 atatcaaaaa gaaaatacta taaagtattc aggcaattat caaggtatat tagcaaatgt
    26041 agatgaaaaa caggctgata tattgagtaa tcatgcagat gttgaattaa ctggtgaaat
    26101 gaatggagta ggtgttgaaa aactggaaga tgattcaaat atttctctag catacatgaa
    26161 tgaagatgct ttgaaattaa atagttttga atttatcaaa ggaaaattgc catcaaaaga
    26221 gaatgaaatt gtgttagata gtggagcttt aaaggcactt ggttataaaa ataaagattt
    26281 aggtgaaaag ataaaaatat cttatgatga ctataaaaat gataaaaaaa ttgaaaaaga
    26341 gttcattata agtggaatct taaaaactag cgaaatatct gaagcaggta aatattatta
    26401 tgctattata tcagaatcat atatgagaaa tactagagat atgtcacaag aagattttaa
    26461 tatttatgtg aaatttaatg ataaaagtaa tttatcaata gagcaagcaa aagaaaaatt
    26521 agataaaatt gctaatgata taggactgga tactattaat actgctgtaa atgaaaatta
    26581 tataaatgct ttaaaaccag atatggaaac gattatgggt ggagtttttg tagggttagt
    26641 aattgtatta tctagtattt tagtaatata caatatattt tatatttcaa tagttacaaa
    26701 ggttcaagaa tttggaaaac ttagagcaat tggtgcaact aagaaacaaa taaaaaatat
    26761 agtgtttaaa gaagggttca tattagccgg aatagctata ccaataggaa taattttagg
    26821 ctatgtactt gcaaatatta taataaaatc atttatggat atagatgtaa aatcatcacg
    26881 attaccagtt atattatcgg ttgtggtaat aagctttata tctgttgttt tatcactttt
    26941 aaaaccaatg aaagtagcat caaaagtatc cattgttgac gcagtaagat atacaggaaa
    27001 taaaataagt aataagagta agagaaaagg atataaaaat ataaatctaa agagattatc
    27061 acatgccaat ttagaaagaa ataaaaaacg tacttacatg acattggcat cacttatact
    27121 tagtggaact atatttataa cagtatcaac tgccttagaa agttttgatg ctgagaaaat
    27181 ggcaagagaa cactttcctt atgatataga agttagacta tctggttatg aaatgaacag
    27241 tgataaaaat cctaaagata atttgaatat tttacaaatg gataatcctc taagtaaaga
    27301 tttttttaat caaataaaga acatggaagg aattaaaaga atagaatctg caagaagtgt
    27361 aaaaattggt atggaggact atgatgttga atttaagtat gaccttttac aaagtataaa
    27421 tgaaaatgat gtaaaatcat taaacaagaa tataatagat ggaaaaataa atcttgaaag
    27481 acttcaaact ggagatgaaa tagtaattac tcatgttgat acagcaaaag aaatgggagt
    27541 aaaagcagga gataaaataa gattaacttt atatgatgga gataaaaaga taaaaaaaga
    27601 atttaaagtt caagcaatag ctatgggggt tccaagtttt ggtataggga aagattttat
    27661 agatagaact ttgaaatacg attcaactag tagcttggga atatatacag aagaaggaaa
    27721 gtatcaagaa atcaaagata gtatcaagaa gattgctaaa aataatggat ttttagagac
    27781 tgattttata gatagtagaa ttgagtcaaa taaggctact atttcattta taaagataat
    27841 gggatacacg ctaacaggca taataggtgt gattggattt atgaatcttg tcaacacaat
    27901 gataactagc atagttacta gaaaaaaaga acttggtatg cttcaagcta ttggtcttac
    27961 taataaacaa ttagtgaaaa tgcttaattc agaggcaata tattacactt ctggaatgat
    28021 gataggaagt attctatttg gaggtatatt agggtatatt gctgttatat ttctaaaaaa
    28081 gactggatta tcttatgcaa catattcttt gccaatagta ccaatcttgt tgatgattgt
    28141 gtgtattctt atagctcaat ttataacaac ttatttgata ggacgaagtt ttaataaaga
    28201 atctcttatt gatagagtaa gatacagtga ataaaatgca aatatttatg gttagtttaa
    28261 ctagcaaaaa acatataaaa aaatatagtt aaagagattc ataattaaat aggttaaagc
    28321 atagtacaga gcaaacaatt taaacagatg tttgctctgt attttattat gtaatcaata
    28381 atatatctaa tatactgata ttattcatgt tagaaaatgt accggtacaa ttctaaaaaa
    28441 gtataaaatt gtaccatata aaatgaaaat tttgtataat aatcgtatag aaaataaata
    28501 ggagctgata tatatgaata agaagattaa ttatgcacca ggaccaactg aaactaggga
    28561 aaatgtaaga ttagcaagag cagaaaaaac aacaaatcca gatatagata ttgattttgt
    28621 tgaattttat aaaaagacat gcgagaagtt tggtaatata attggaacaa aaaacgatgt
    28681 ttacatattg agtggtgaag gaatattagg tcttgaagca gcatgtgcat cacttacaga
    28741 aaaaggagat agagtacttg taattgacaa tggtatatat ggagaaggtt ttaaagattt
    28801 tgtaacaatg tatggtgggg agtatgtgct tttttcaagt gagtatacta aaagtataga
    28861 tattgatgaa ttgaaagcat ttttagatga ggatagtaat tttaaatatg caacagtagt
    28921 gcattgtgat actccaactg gcgtattaaa tgatgtaagc aaaatatgtc cattacttaa
    28981 aaaatatgga atattaactg tagttgattc tgtagcaggt atggtaggag aaagattaag
    29041 tgtagatgaa tctaaaatag atataatatt aggtggttca caaaaagcta tttctgcacc
    29101 agcaggactt actatagtcg gaataagtca agatgcaaaa aattgtataa aaaatagaaa
    29161 aactgatgta ataggttttt attgtaattt aaatatatgg gaaggctatt atgagaaaaa
    29221 atacttccct tatacaatgc caataagtga cataatgggg cttgataaag cacttgataa
    29281 tatattagaa gaaggaatag aaaatgtatt aaatagacat gaaaagatag cttatagtgt
    29341 tagaaaatct attgaggaat atggtctaga actattttta gaagaaggat attctaatac
    29401 agtcacagct ataaaaattc ctgaaagtat aggagcttta gaacttactg attatatgct
    29461 taaaaattat aatacacttg ttgcaacatc actaaatcaa tatatggata ctattttaag
    29521 aataggtcat atgggagaga atgcaaatct aaataaaata gaacatgtac taaatgtttt
    29581 ggataaaagt ttaagtgcat taggattcaa aggaaatgga aatttgttaa atttatttaa
    29641 taagtattat ttttaataga tagggggata tagtatggaa gttacagcta agcaaaaatt
    29701 tacaacgaaa gacatggtgg aaacctcact attaatagca ttagtattta ttgcaactaa
    29761 atttataaac ataagattac caatatctat aaatggtggg cttgtgcatt taggaactgc
    29821 aatgttgttc atatcagcaa tagtatttgg aggtaaaaaa ggtgctttat caggggctat
    29881 tggtatgtca ctttttgatt tgatatctgg gtggacttta tgggcaccgt ttacctttat
    29941 agttagagga gttatgggtt atttacttgg aaagattgca tgggcaaatg gtaataatgg
    30001 gaataatttt ttaatcaatg taataggaat atgtgtttca tcaatttgga tgctatttgg
    30061 atattatgta acagaagtta tactttatgg taattttata gtacctctta cttcaatacc
    30121 aggtaattta atgcaagtat tgataggtct tataatagcg cttcctattt ctaaggtatt
    30181 gaaaaaatgt ataaaataaa tataaagtga actaaaattt atgatagcat aaattatact
    30241 gtataatatt aggatggagt acataattaa aaaattttag tatagaggtt agttcacaat
    30301 gttatcagtt acaagatatt caatcaaaaa tgttcgttta aagccgtggg taaagtttat
    30361 ttggtatttt gagacaaaat caaatatact gttaaataat aagttacttc cgacagacag
    30421 tatagatatt attctcaatc tttctgatgt tatggaatat aaaattgaaa atcaagacta
    30481 tactgctagt aatatgcatt ttaatggaat aagggataaa catggattta ttattcaaca
    30541 tggaaatata cgtgttatag ggatttcttt ttatccattt ggtctctatc catttttaaa
    30601 gataccaatt tcagagttta acagacaaat tgttgaccta gaagcagtat cacagctatt
    30661 tgcaaaaaaa ttggaagagt cattaaatcc aacacaatca gtagaaaaaa ttgttttata
    30721 tttagaagaa gtattattat ccatattaga agaagattta atttcaaata aatatgtaaa
    30781 gcttctaaat tcatttatat atgttaatag atatagcaat ataaaagcat tttgtgatga
    30841 tacaaatata aatattaaaa cattggaaag aatctgttta aaatatacag ggtatacacc
    30901 taagatttta aagagaattt acagatttaa aatggcaagc aatcaactta tttataatta
    30961 taaagatgat gaactttttg attttattta tgaaaatgag tactatgacc aagcacactt
    31021 tataaaagaa tttaaaaaat tttcagggac gtcaccaatt aaatttattg gtgagaataa
    31081 gacgattaaa gaaaatataa agtacagcta tttataatta tactgtcgat tttttacaat
    31141 acctccaatt tattttttga tatgatatag gaaaataaat tggaggtttt acatatgaaa
    31201 attattacag aaatagttga gtttaatgtg gaagaaaatt tatcaaaaga agagtttata
    31261 gaaattgtaa atgacttaga attaaaattt cattctattc aatctggttt tattgatact
    31321 gagcttttat atgatgaaaa gtctcaaaag tggattatga tacaacattg ggaatctata
    31381 gaagacctca agagtgcttc tagtaaaatg tttaaagatt cttcaactga gaaatttaga
    31441 aaagctttaa agaatcaaac tgttaagatg aatataatac cacaaattaa aagttggaaa
    31501 ttatagaact taatgtaaaa gatagttaaa tagtatcaaa ctaaattagc caaataacat
    31561 tttgtattta aattgttatt tggcttttag tgtttatttt aatatgagtg ttatatacta
    31621 gaaaaaccaa ccttaaatac tactatctaa aagcactatt gctgtacgag aggcaatagg
    31681 cattttagaa gaaggaggag ttgagctaaa gtatacatca taatctctta agttttcttt
    31741 ttttgtgttt cctccaaact ctaccatatc agtatttaat atcgttttgt agtttgtatt
    31801 ttgaaacttt gaaatatcaa ctgattgtat tagattaggg tggaaattaa atataaataa
    31861 atatttgccc ttactgtaca ccaaaatctt tttatcatta tccatatgta taagttcatg
    31921 actattttgg ataaaaatat cactgtattt tgtaagttcg agcatagatt tatcaaaatt
    31981 taataattgt ttatacttta agttgttatc ttctgaaagg ctccattgtc ttctggcata
    32041 cttatagctc caattgttgc cttctcgtgg aaaatcaatc cactcaggat gtccaaattc
    32101 atttcccata aaatttagat atccttcacc tgctagagaa aaagttatta atttaattaa
    32161 tttaataaga gatattgctc tattgataac atggttattt gagtttattt ccatattcca
    32221 gtacatttcc ttgtcagcta gccaaaaaat aattgtttta tcgccaacta atgcttggtc
    32281 atgggattca caatatccta tatttttttc tccaggtcgt ctagtagtaa gttcatacca
    32341 catttttccc aaatcccagt cttcatcaga taagttagag atagttttta tccaaaaatc
    32401 aggtactccc attgcgagtc tatagtcaaa tccaattccg ccgtctttta tagggataca
    32461 cataccaggc attccactca tatcttctgc aatacttatc gaattaggtt taatttcttt
    32521 tattaattca tttgcaaatt ggagatatgt tatagcttca atatctgtat tcatactaaa
    32581 atatttttca taactatcaa atgaaactcc aagaccatgg ttatgatata acattgaagt
    32641 cacaccatca aacctaaagc catcaaaatg gtactcattt aaccaaaatt ttatatttga
    32701 aagcaaaaaa tgtattactt caggtttacc atagttaaaa agttttgtac cccaagcagg
    32761 atgatttccc tttgaacctg agtggaaaaa ttgatgttca cttccatcaa actcatttat
    32821 tccttctaaa gtattcttta cagcatgaga atgaactaaa tccaataaaa cagcaatccc
    32881 cattgaatga gcagtgttta tgaggttttt taagtcttca ggagtaccaa acctagatga
    32941 gattgcataa aagtttgaaa cttggtatcc aaaagatgca taatatggat gttccataat
    33001 agccataagc tgaatggtat tgtatccagc tttttttatc ttaggaagta ttttttcagt
    33061 aaattcatta taagttccaa tagattcgct ttcagtagac atacctatat gacattcata
    33121 gattagtgga taagttatgt tttttaagtc aaaatcattg tcagtccaga taaatggagt
    33181 ttttggttgc catatttgtc cattaaatcc accaaaatct ttttgaatta ctctttttat
    33241 atataatggt atacggtcaa atgtttttcc atttgcagta acttgtacct ttacctctga
    33301 tttgtgaggt aagctatttt gaccaggaat aaatatttcc caattaccag acccaatttt
    33361 tcttagagga tgagattttc tattccaatt attaaagtca ccaattagtg acaaactatc
    33421 tgcatttgga gcccattccc tatagaagaa tccatcattt gtctgatgaa atccatagta
    33481 aagatgagca tttgcaaaag aactaaaatc tttatagttt ttcaatgttt ttgatttcat
    33541 attctcataa tgtttcattc gcttttttat atcagattca aatggttgta ggtatacatc
    33601 aatatctaaa attttaaatc ttttttgact tttcattgta tttctcctcc ataataaata
    33661 ttacatctaa aaaataatat ttatctcata ctatcttctc tatataattg atatatatta
    33721 tataatccta ataaaaagct taagccacca atgattaatt tcataattta cctccctagt
    33781 atttatactt atatatcgta ttcatcaaaa tttaaaagtt tgtttaaaac tcttttaata
    33841 atatcataat caaagccttt ataggaaaga tgttgagaaa ttttttgata tattttcttt
    33901 ttatcttctt tctttactct ttcatacctt ttttttgcta gatacatagc attttcaaat
    33961 tcagtgtcct tgtctaattc agatactgct tcattgattg tacttctatt gataccttta
    34021 ttatataaat tctgcttaat tctgtttttg ccacatttat ttaggttaac atttgtgtta
    34081 acaatttttt gagctaatac actgtcattt acgagattat aacttttaag aaaatctatg
    34141 accctctcaa ttatattttc atcaaattct gatgatagtt tttcttttaa ttttttttca
    34201 gattggtcag catgagataa aatatttaat gctttatttt tagcttttat atacatttca
    34261 tcatctaaaa taggttttaa ttcttcttca tttatttcat tccccttttt taaattaaat
    34321 gtataaacaa gttctttaaa tatagcaata aaaaatttat catctacata aatattaact
    34381 ctatcatcat ttcttttttg ttgttctatt tttgtaatta tacccataag tcctcctttt
    34441 ttatatgtaa ttatattaac aaaagcaact aataaaattt aacaaaaaac ttatatttgt
    34501 atgttatatt ttatcaaaat taagacaaaa tagtaaaaag ttatttttat taaaaagtaa
    34561 agtagaatca tgttaaataa ttattttttt aagtgttttt tagcatataa atataattat
    34621 atacccaaaa aaacaaatta taagctttaa gaaataaaaa ataatggtac aatagtatta
    34681 taacattaaa aggagacaaa atatgagaag tgaaaatcta gttaagatgg cagagttgaa
    34741 aaatactgaa aaactagaga aatttaatcg ccataaaggc aaaatcaaaa taggtatatt
    34801 gggaggtact tttgacccta tacactatgc tcatttagca acagcagaat ttattagaga
    34861 caagtatgac attgacaaaa taatctttat accatcagga aatccaccac ataaattatg
    34921 tatcactaca gataagtatg atagatataa tatgacactt ctagcaactg aaagcaacga
    34981 agatttttta gtttcaaaag tagaaatcga aagaaagaaa aggacttata caatagatac
    35041 attaaaatac ttaaagaaaa aatacaaaaa tgcagacatt tattttataa caggtgcaga
    35101 tgcaatttgt agtgttgaag agtggaaaga tgtaaagaaa aactttgagt tagctacttt
    35161 tatagccgca actagaccag gaattagttt gttaaggtca caagagacta tagaaaaact
    35221 aactaagaag tataatgctg acattataac agtttatgtt ccatcactgg atatatcgtc
    35281 cacatatata agggaacagc taaatgaagg caagtcaata cgttacttag tacccgaaaa
    35341 tgtagaaaat tatttatatg aaaataaact atatcaatat ggagatgatt aaatgaactt
    35401 agaaaatatt aaccaaagac taaatcaaat gctaccagtg gggaggctta gccattcaaa
    35461 aaatgttgca aaatgtgctg aaaaattatg tgagatttat ggatgtgaca aagaaaaagc
    35521 ttacttagca ggaatgattc atgattgtgc aaagtattta agtgacaagg aaatagagga
    35581 ttatgtaaat aagtatgaaa tatatttaga cccaatagag gatggaaatc gttccttgtc
    35641 tcatagcgta attggggcgt acatatgcga gtatgaattt gaagtagaag atgaagatat
    35701 tataaatgca atcaaatatc atacaacagg gagagaggac atgtctcttt tagaaaaaat
    35761 aatttacata gctgatttaa ttgaagaagg aagaaaattc ccagttgtag atacattaag
    35821 agaattagca tatggaggga agcttgatga agcactttta acttctttta ataatacttt
    35881 aatgtttgtc atcaataaaa aagaagagat acatccaaga acagttatgg caagaaacta
    35941 tctaattaaa gaaaagttat tataaaaaag ctatataaag gcaaacatat taataaattt
    36001 aaatttgact atgttacaaa atcgtattaa tatgttacaa taactaagtg tattttaatt
    36061 aggaaagtga ggaattttta tatgacagtg gaacaaatga caaaaatagc atatgatgcc
    36121 atagaagata aactaggtca agatacagtt ataataaata taggaaaagt ttctagtttg
    36181 tgtgattatt ttattattac tacagcatct tctcagagac aggtaaaagc tattgctgac
    36241 aatgtggaag atgaattagc aaaactagga ttagagccaa gaggtaaaga aggacaagga
    36301 actcaaactt gggtactcct tgattatgga gacataatgg ttcatgtatt taatgaggaa
    36361 aatagagggt tttataattt agaaaaatta tggaaagatg caccttatat agatattgac
    36421 acattagcat aaacatgata atatatgtta ttataattag aaaatttcaa aaattatatt
    36481 aaattgaata gactagagca gtaaaagatt atattttttc agagagttag tggaaggtga
    36541 gaactaatat tatataactt tgaacttact agattaaaat ctattctcca tggctggatt
    36601 aaaagctatc taagagagtc tatatatgta gtaggctaat tagggtggta ccgcgaagat
    36661 ttatcctcgt ccctaaacgt aagtttagtg acgaggattt tttattttca aagaattatt
    36721 tggaaattat aagtaaataa tactaaataa ggtagttata cacaattaaa aataggaggc
    36781 aaaatatgag cgtatataat tttaaagaag tagaatcgaa atggcaaaaa atctggaaag
    36841 ataataatca gtataaaatg gatactgcac aaactgaaaa acctaattat tacacattag
    36901 aaatgttccc ttatccatct ggaaaaatac acatgggaca tgttagaaat tattctatag
    36961 gtgatgttgt cgcaagattc aaaaaaatgg aaggatataa tgtacttcat ccaatgggat
    37021 gggattcttt tggattacca gctgaaaatg cagctataaa acatggaata catccgcata
    37081 aatggacaat ggaaaatata gaagaaatga aagagcaatt aaatttatta gggattagtt
    37141 atgattggga taaagaagtt gcaacttcaa ctccagaata ctatagattt acacaagaaa
    37201 tatttttgaa gtttttagag catgggcttg catataagaa aaaatcatat gttaactggt
    37261 gtccttcttg tgagactgtt cttgcaaatg agcaagttgt tcaaggagca tgtgagagat
    37321 gtaaagcaac agtattaaag aaagatttag aacaatggta ttttaagact actgagtttg
    37381 cagaagaatt acttaatgac ttagatacat tagatggatg gccagaaaaa gttaaaacaa
    37441 tgcaaaaaaa ttggataggt aaaagtacag gagcagattt agtttttgat atagatggaa
    37501 ctgataaatc tatgacagta tttacaacta gaccagacac aacttatgga gttacttata
    37561 tggtacttgc tccagagcat gaattagtta aagaattggt tgcagggact gaatatgaag
    37621 cagatgttga agcttttgtt caaaaaatgc atactatgac agaaatagaa agaacagcag
    37681 ctgatgtaga aaaagaagga atgtttatag gtagatatgt tataaaccct ttaaatggca
    37741 agaaagttcc tctatggata gctaactatg tattagttga gtatggaacg ggtgctataa
    37801 tggcagttcc agcacatgat gaaagagata gagattttgc tgaaaaatat aatttagaca
    37861 taattgatgt aataacagaa gataacaaaa tgataaattc agaagaattt aatggattag
    37921 atgcttcaga aggatttgaa ggaataatcg ataagttaga aaaagaaggt agaggaaaga
    37981 gaacaattaa ttatagactt agagactggt tagtttcaag acaaagatac tggggttgtc
    38041 ctatacctgt ggtttattgt gatgaatgtg gaatagttcc agttaaaaag gaagatttac
    38101 cagttctttt accaacagat gttgaattta ctggaaaagg ggaatctcca cttacgactt
    38161 caaagcaatt tatgtcaaca acttgtcctc actgtggaaa accagctaga agggaagttg
    38221 atactatgga tacatttgtt gattcttctt ggtatttctt aagatatgtg gatagcaata
    38281 atgaaaatga accatttagt aaggaattag ttaatagatg gcatccagta gaccaatata
    38341 taggtggagt agaacatgct ataatgcatt tactttatgc aagatggttt gtaaaggcat
    38401 ttaagagtat gggaatggta gacttcaatg agccatttaa aaacttactt actcaaggaa
    38461 tggtacttat ggatggttct aaaatgagta agtctaaagg gaatacagta tctcctatgg
    38521 atataataga tgagtatgga gcagatactg caagactttt cgtattattt gcagcaccac
    38581 cagaaagaga tttggactgg tcagagcaag gtgttgatgg atgctttaga ttcttaaata
    38641 gggtttatag attggttgac gagttagcag atgtggttaa aaaggatgta gagtttggag
    38701 aattaaattc ccaagataag gatatgagat atactataca ctctacactt aaaaaagtta
    38761 ctgctgattt aagtgaaaaa ttcggattta atactgctat atcagctctt atggaattaa
    38821 taaatgatat gtataaatat aaagagttag ataatataaa cgaagcagtt ataaaagaag
    38881 gtgtacaaac tatagtaact ataattgcac catttgcccc tcatttaggt gaagaactat
    38941 ggactatgat aggtaaagaa ggaagtgtat ttgatataga ctggcctaaa tatgacgaaa
    39001 aagctttagt aaaagatgaa atagaagttg ttgtacaagt taatggaaaa gttagaggaa
    39061 aattaactgt taactcaaat atatctaaag atgagatgga aaaggtagct ttagaagatg
    39121 aaaaaataaa aggattagtt gaaggtaaaa ctatagttaa agttgtagct gtacctaaaa
    39181 aattagtaaa tatagttgtt aaataactca aaaatatgaa caaaaatata aatttataaa
    39241 ataaatgagg ctgtctcaaa atagagataa gccttttttc attgttgaaa ttataaaaat
    39301 agatttgatt ttatacaaaa aaatgattaa agaactaaaa agttcattct tatataccct
    39361 agttgttgtt ttaaatatta ttataattaa tgttaaatcg agttaatgta ttaagtggta
    39421 tgtaaatcat tcagtttcca aagtgttgtt cgtcaaggaa ctgctctaag cttaaacgaa
    39481 aaaaatataa ttattgtatt ttgaaatttt tttctatata atgaaaacag gcaaaaaagg
    39541 tgcatatcta tgctttatat gaaacaccca gacaacgaaa ttcagattca tataatagct
    39601 accatgtttc taaaaaggaa cttgtaaaaa agatagcgtt tcaacttccc agttgattaa
    39661 aattatcagc aggaaaacaa gtatggtcag cagtggtatt ctaatgggtg ttgtcgatat
    39721 atccaagttg ggattgtctg aggatgttat caaataactt gtgataggtg cagtagatgt
    39781 ggagattcct gatacggatt tattctcagg ggatggttgc ttcgggagat atggagcgta
    39841 accagtttat tgatatggta accatttttt gtctaatttg atgaaagaat cccaagaata
    39901 ccatacagaa gtaagacagg aattaactgg tggtataaac tgataaaggc aaatttaaaa
    39961 attttgatag gatgatttta agatttatct tctattttgt tttttagaaa taattgaaat
    40021 gttatgagga ggtatgtaca aatggagact gtaacaaata atcaatcagg tgtagaaatt
    40081 caactcagtc tgtttgaagc tatcaaagat ttattgttaa ttaatcctat tttcttgttg
    40141 ggaattatct tgattggtat tttcttagtt gtaatattca agaaaaatag tgatattcca
    40201 aaggtcaaaa catctatttt atcactggca atgtattact acttatgttt aacactatcg
    40261 catattgttg gtatacctac attcggtgaa tatataagac tgtcacagtt aggggaaacg
    40321 ttctttaatc caaacataaa tcttattcct tttagtgatg gatttagttt gagttttatt
    40381 ttgaatattt tactttttgt cccattaggt tttttatgtc cgcttataag caaaaccttt
    40441 gaacgtttga gaaatacatt cttgattggt tttggattat ctctttttat cgaaactatt
    40501 cagcttttta cgttacacag agcaaccgat atagacgact tactcacgaa cgtaattgga
    40561 acaataatag gctatttctg cttcaaactg attgctaaat tgcgaattgt aaaactacat
    40621 tcagatgatg actctatgga acaggattac acagtatgta ttccgattgc cattataata
    40681 gttgccctta tattaggatt ttttagttaa gttccaaata gctaatttgg gaatccagac
    40741 aatataacag atactatgtt accttttaca ggagcatact atctgttata ttgtcaacat
    40801 cctattttat ggtttgtgtg tagtttcctg taaactgaac taaataatta aatagaagct
    40861 attagaatta ataataacag atagatatta ataagcataa acaaatagta aaatgtgtag
    40921 atatagacgt ttttaagtga aactattata aaataattga ctgataatca actgacaaaa
    40981 cctatttttt taggtttaac tgacatttaa ctgacagtca gtttttacta tttaaataga
    41041 agttcgctta gattgtcgga agcttctttg tccatttctt taagtacatg agaatatcta
    41101 ttcatagtta tttttatatc tgtatgaccc aatctttcag aaacaacttt catattagtt
    41161 ccccctaaaa gcagcagagt ggcacttgta tatcttaaat catgtattct aatctttttt
    41221 aaattatttt ttttgtaaaa ttgtgaaacg tttttcttag tgaagaaggt agaaacggat
    41281 ttaaattggt gtttagacaa actaagttat ttctgttttc caggatacct tacaatttta
    41341 atttgctttg tcttagtttt tcaattttca atttttcaat taattctttt ggagctgata
    41401 aagctctttt tgattttggt gtttttggct ctttaaaaga tattttgcca ttagaataga
    41461 caagaatttg attaacattt atcagattgt tatctaagtc aacatctgac cacctaagcc
    41521 caatagcttc tcacattctt aaacctagaa gtaacattaa aagaataggt atttctatat
    41581 tattaccaag taacttttct attagcaata atacttcttc tctattgtat atttcatttg
    41641 tagaatattt ttctttagaa ggaagtttta taaaatcaca tgaattttct tgtatttctc
    41701 ttaatctata cgcttccctt attacagaac ttagaaagct ataccttact ttagcactag
    41761 taaaggtaga attattaaag ttataattta caaaagcttg tactgaacta ggatttactt
    41821 ctgtgagttt tagattctta aaaaaggttc tatgtaattt ttaacccaag attttgtatt
    41881 tgtaacagta tatggagacc aattattttt attcatgtct atatatttat aacatctttc
    41941 tacaaatgtc ataccttttg gagcaacaaa cttattatta tttatagtag actttatttc
    42001 aattaaatgt ttttcagcat cctttttctt tttatagctt ccataacttt tttgtttctt
    42061 tttgccagtt tcttattcca catatacata gaatttttcc catctttttc ttataaaagc
    42121 tgatttgata ttcatatatg tacgctccct ttataagtta gttttataaa agaacagttg
    42181 gactgctcta attatgtcat tatcttttta attctttaca gttacattat aacacgtatt
    42241 tgtatacact taaattaaca ggaagataaa tatcgttaaa ggaggaaaag aaaatttaat
    42301 gtagaattat gtaagatata tagtatttca tatataaaag ggggagatat tgtgaaatta
    42361 aagaaattat tatcactagg gttagccgtg tcaatgtttg ctgctggtcc tatatcagct
    42421 aatgcacttg atacaattta tactattcaa ggaaaagata aatatgaaac ggctgctctt
    42481 atagctgatg aacaaaatta tactacagct atattaatta atgcagacag cacaatggct
    42541 gatggattaa gtgcgagtgg acttgcagga gcaacaaatg caccaatttt tttaactaag
    42601 aaaaataaca tacctaatgc aactcttaaa agagtagaga aagctaaaaa ggtatacata
    42661 ataggtggag aaagttctat tgataaagca acagaaactc ttctaaaaga taaaggaata
    42721 gaggctaaaa gacttcaagg tagtgataga attaagacaa gctataatgt tgcaaaagaa
    42781 ataaactcaa ttaacaaagt aaataaagtt atattgacta atgcttttaa aggagagcct
    42841 gatgcaatga gtgctgcacc tgtagcagtt agagataaag cagctatagt attaactgat
    42901 ggaaaaagtg ttccatttaa tacaactggt gtagaaagtt atgtaatagg tggtacttca
    42961 tcaatgagtg acaaactagt taatgatact aattcaacta gattaggtgg agtagataga
    43021 tatgatacta ataaaaaaat agtaaataag ttctataatg gcgcaaaaga attttatata
    43081 gctagtggta ctgatttagt ttatgcttta gttgcttcac caatggctaa aaataatcct
    43141 attgtactag ttgatattgg aagtaataaa gatatactta aaaatgctgc aaaagtgact
    43201 gggataggaa atctaagtga taaaattatg ctagagtgtg aaaataccat caataatatt
    43261 agtcttccgt cttcaaataa aaatataata tgtggattaa agattgattt tgattcaaag
    43321 cacataattt ggcaagataa aggaagttat cttgaatgtt atgatgataa ccttgaatat
    43381 tatactgaaa aatataaaga cccaacagtt cctataaata tagaaaatac aagtacacaa
    43441 aatttagatg taacaaaatt aaaagtttat ggagaagcta attcaacatt atatatgggg
    43501 caatatgcta aaataaaaat ggattttaat agtttcggtg tattaaagcc aggagaaaaa
    43561 tgtactattt atttagatat aatttcatta gatccatcaa gaagcatgac attaacattt
    43621 tcttatgtag gtgataaaga aaattataaa tatgaacaag gattggcaag tagaatatta
    43681 ttttataacc cagatggaga agattttttt gaatataaat aactagtggg tatgtaaatt
    43741 aataagggtt ttataagttt aattttttta ttttcgtttt atattaacta tgtggtatgt
    43801 aaatgtctcg atattgctca tatgttgagt tattatattt agtttcatat gaactatatg
    43861 gattttaaaa ttaaaaatac ttaaaaacat ttactttaat agtaggtgtt tttttgatta
    43921 aaagaatatt attataatgt aaaaagtaat aaataggtaa aatatgtaag aattatatgt
    43981 tataatattt ttagcaagaa gatgtaatct acaatttata gagtggagtt catgtatcaa
    44041 aaaattatcc tcccgacgct aagaagggag gtgaatatac atggataatt ttttacaagg
    44101 catactagca agtctatctg ctagcttaat agtttatata gctagcaaac tatttagaaa
    44161 gcgtaaaaaa ccactcaaag cggcaactaa gagtggttgg gaatttgatt taaaaatcag
    44221 attccataaa actaagtaat ttctaaatta tgaactccac tctacagcaa aatagattgt
    44281 agttcttctt gcttttatta tatcacaaat tggtacagat attcaaaaat aatattttta
    44341 tgatataata aagtcataga aattttgcag tgttcgattt tttgaagaaa ttaaggctta
    44401 acagttgaaa tataaggcat tgaggacttg tgataagtgt tatcaattgc actactcatg
    44461 gttcactgca aatttgagag atttgtatat gtgtaggcat tggaaatact caatttattt
    44521 tggggtttta tattaactat atggaatgta aatatttttt ttatatataa acttctaaac
    44581 ttttacaaaa gttttatatt aactatatgg aatgtaaata cacttccaac aagcattgta
    44641 gggttgaagt ctacaggttt tatattaact atatggaatg taaattaaat cgtatttata
    44701 attatatcta cacttagtaa atgttttata ttaactatat ggaatgtaaa tccaatagac
    44761 cctccaataa ctccagatat tccttctggt tttatattaa ctatatggaa tgtaaataat
    44821 gaactatcta aaccaaggtc ataatttaat tgagttttat attaactata tggaatgtaa
    44881 attgtatcca aaaaattaca ataatcatac gaattgctaa tataagcagt caatatatgt
    44941 gtacatttat ccattttatc tctaaacata taaattatta tccccctaaa aaactttcat
    45001 aaaaacaaaa agaacaatat ctctttggca actggctaac ataactcata agatatttat
    45061 ataagtctta gtccctatag ctttgcgtca ctagatttct ctagttttgc cgatttagtt
    45121 ttattctata actaaataat acaatagaat tagttattat tcaacaagat tgtttgaaaa
    45181 ttgaataaat ttataggtat gaacgtaatt tcacacttaa aaacagacta aatacgtaga
    45241 atatatagaa aaatttacct gtagtttttg tgataaaaag ctcctattat taatttaagc
    45301 tagataagtt tgaggaagtg acataaattg aaagaaggaa tatattatgt tgaataaaaa
    45361 attaccagat gcagaattaa aaattatgaa atacatatgg aatactggtt ataaaactgt
    45421 aatatcaaaa gatgttgcag attaaataga aaaaacatat gcttggaagc atacaactac
    45481 aattacactt ttagctagat taactaaaaa aggttttttc atatcgcaga gaattgggaa
    45541 acatgtacac tatagagtat taataaaaga gaaagaatat ctcaaaatag agggaaaaag
    45601 aatttttgga ggtctacata acaatccatt atcagaacta atttcaaaat tacatgatgg
    45661 agaagaaata actgaagaaa aaataataga aataggaaat tggataaaaa gctggaaaga
    45721 tgaagattaa taaataaaag gtagctacta atataagtgc tacctttttt cttgtggata
    45781 atattgggga taagttgtgg aaaatttgtg taaaaattgt ggataaaata ttttgctgac
    45841 atttaactga cataagtatt agattttgat ttaaaaatgt tgaaatatca ataaataatt
    45901 aaatagaagt tattagaatt aacaatagat tcctttttca aagaagtctt tgatttcatc
    45961 aaggttatca gtttttccaa gtgctaagat aagttttatt ctagcttttt gacctggtaa
    46021 gtccccacca aatatacaac caagattttt taaatctcta ccagaaccaa agtaaccata
    46081 actatcgaat actctacctg aatgacatct agaaactata actacaggaa gtcctttttc
    46141 tctagcatat tcaactccag aaagcatttg aggaggaata ttacctctgc ccattgcctc
    46201 aataactata cctttataac cactatcaac agcaaatctt ataaagtcag cattttctcc
    46261 tacatatgct ttaaataagg caactttaga ttctacctta tcagtatcta taattgttct
    46321 atttacaata tctcttgtaa ggacaagttc gttgcagtca attattccta atgggccact
    46381 agttagagat ttaaatgtat ttagagaaag agtatttgtt ttagtagctt cagaagctaa
    46441 taatacttca ttgtttaaaa ctacaaggac tccttttccc atagcatctt tggatactgc
    46501 agtacaaact gatgcagata aattacttga accatcatat ccaagttcag aactacttct
    46561 catagcacct gtgactatta caggtttgat gttgtcaatt gtaaggtcta gaaaataagc
    46621 tgtttcctct aaactatctg taccatgtgt tattacaaca cctgtaatat cttttcttgc
    46681 taataaatca tttacataat ttttcaattc catcattcta taaggtgtta tgtgaggtcc
    46741 tggaatttca tcaaaattaa aaacttcaac atctgcaact ttatcaatgt tggtaaccat
    46801 tgatagtatt tgttcacctg ataaagttgg tatagctgct ccgactttat catctactgt
    46861 catagatata gttccaccag taaaaactat ggcaactttt ttcttaatac tcatactatt
    46921 ctctgccttt cataaataaa atttataatt ccgataggat tatatcaaaa aaagtagtta
    46981 aggtctacat aaactctttt attcatataa tttagatatt tcagtgtaat ataattattt
    47041 cttaattttt tgccattcaa cgatataacc atttaatatc tctcttatgg cttttcctat
    47101 cttagtataa gcttcatcat atagatttgc tagagatatt ctaattgacc attcagggcc
    47161 atagaatcca tttccactaa gtaaaactac tgaatagtca ttagctaatt tataaagaac
    47221 atctactgga gatgcagttt tacttataaa tttaaataag tcttctccgt agtttaattt
    47281 agcccattct tcaatatcaa attgagtgta atatgcagca ttgtttttgt tttcattaat
    47341 tggaagctct aaagcttcaa ataatagttt ttgacgtcta tggcagatac tcatattaag
    47401 ttttttgtag gcatctactt tgtcaatcaa tgcaaaagca gagaaaaacg ccatttgtac
    47461 ttgctgtgga gtagaaagac cagcagtatg gttgagagca acaagtctgc tatcagcaac
    47521 aactctttcc ataaaggaaa gactagaagg gttaagactc atatcactgt aacgcttatc
    47581 tactgatttt tttaattctc cagttaaatc atttattttc ttatcaaaaa catttttctt
    47641 atgaagggca aatgtaccaa gtctccatcc tgtaactcca aaatattttg aataagaata
    47701 tactccaaca gtgttgtaag gtagttttga cattaaggat gaaaaatctt ctacaaaagt
    47761 tccatataca tcatctgata ttatcattaa atctttatta taattttcaa ttacatctat
    47821 tagattatta caagatgttt catccatagc tatagaagca ggattattag gattaacaac
    47881 gaataaagct ttaatagatt tgtcacgaag tttctctaat tctttttttg tatattgcca
    47941 tgtatgagca cctttttcat caacttcatt agcatttata tttaccactt taaagtcgta
    48001 acgaggaagg ttaggtattt caagataagg tgtaaatatt ggagtcatta aggctatggt
    48061 atctcctttt tttagaagtt catttgccat taatgaatca aatatatagc acatagcagc
    48121 tgtagcacct tcaacagcaa aaatttctac atcaccatat ttacctgata tatcatattt
    48181 catttcttga actaggtaat cgtgtactat tttttccata tgaggtaaca ttctatctgg
    48241 aagtggatag ttatcaccaa taattccatc agctagttca tgaacaaatt catctccatc
    48301 aaatccaagt tcatttatac caaagtttat aatatctcta gctaaatatg ctccaggcat
    48361 atctatattt tcatttataa atttaaaaaa tctttcttta ataccctttt tttgaggcat
    48421 tccagccaaa tgacctaaat cccaattaga acgagtttca gtaatagcga aatgaccaaa
    48481 agtaaaaaag gcttctctag cagttgaaca agtccagttt ggatttccac gacctgcatc
    48541 aagtaattct ctgttatttt cttttgcagt gtattttgca atatctatta atttgtcctt
    48601 aaattcaaaa gggcttattt ttccatatat gtttttgatt tctttataag tatgattttt
    48661 catgttaaat tcctccttat gtaataagtt tcacattttt ataataaaat aaacaagttg
    48721 caaaaatgat tatactttaa ttataatagg tttatagaaa aagtaaagta tgaaattaaa
    48781 ataataactc tatttagcct tattaaatat atgtt
//
LOCUS       DAMJVG010000022        48118 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.022, whole genome shotgun sequence.
ACCESSION   DAMJVG010000022 DAMJVG010000000
VERSION     DAMJVG010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 48118)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48118)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48118
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.022"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            193..3739
                     /locus_tag="PC512_001386"
                     /pseudo
     CDS             193..3739
                     /locus_tag="PC512_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453516.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
     gene            3924..5858
                     /locus_tag="PC512_001387"
     CDS             3924..5858
                     /locus_tag="PC512_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgiQ family radical SAM protein"
                     /protein_id="HDF2441143.1"
                     /translation="MENKFLPISKQDMIDRGWEELDFVLVTGDAYVDHHSFGTAIISR
                     VLESAGYKVGIIAQPDWRTTDDFMKLGKPRLAFLVNAGNMDSMVNHYSVSKKHREKDM
                     YSPGGKMGYRPDRATIVYCNKIREAYSDVAIVIGGIEASLRRFAHYDYWSDKVRKSML
                     IDSGADLLVYGMSEKQIVEVANALNDGYDPKYIRHIDGTCYISDTLEEIYDKYILIPS
                     YKEICEDKMKYVEAFKIQYDEQDPFRGNIIVQPHGSKYLVQNKPEKPLSREELDEVYG
                     LPYQKTYHPVYEKFGGIPAIEEVKFSIVSSRGCFGSCSFCAITFHQGRAVQSRSEKSI
                     IDEAIGITNLDDFKGYIHDVGGPTANFRRPACKKQITKGACKNRQCLSPSPCKNLDAD
                     HSEYLHLLRAVRKLPKIKKVFVRSGIRYDYVMADKNNKFLRELIEHHVSGQLKVAPEH
                     ISEEVLKYMQKPAGKTYDKFRQKFFAINEELGKKQYLIPYLMSSHPGSTLNSAIELAE
                     YLRDTHYQPEQVQDFYPTPGTLSTTMFYTGIDPLTMKPVYVPKSKRDKAMQRALLQYR
                     APRNYDLVYSALVEAGREDLIGFGHRCLIKPKNEKPYFNRNNSKKNVSKGTNKNKKTN
                     TNNRSNKNQQKSSTKKKKKH"
     gene            5964..6959
                     /locus_tag="PC512_001388"
     CDS             5964..6959
                     /locus_tag="PC512_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2441144.1"
                     /translation="MKKYISIILLVVLTMVVLVGCSPGKDNPKNKELSVVKQVKVAVP
                     DGLPAVAIAKLANENPEIKEGYETVYSIEKTPEAISTRVMKKDADIAIVPSNMAAIAY
                     NKTSSYNIVGTVGMGSLYLVSTENIKDYSDLVGKEVGCTGKGLTPDITIKSLLLQKDI
                     NYSDIKFNYVNSASELVPLLATGKVKTGIVPEPALSALMSKNPDIKIIKSLNDSWKEV
                     SGSKDGYPQSTLIVKSEFLRDNKDFVDSFVGQLSNSIDWANKNPEELGAYSEKIKIST
                     ESKIIGKSLERANLKYIPVKDMIKDYKNYYEKLANFDDKTLGGKVPDEAIYFVEK"
     gene            6931..7716
                     /locus_tag="PC512_001389"
     CDS             6931..7716
                     /locus_tag="PC512_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HDF2441145.1"
                     /translation="MKQYTLLRNKKNKEQFIDKMEVTLSCVILLFLWQIIALKIDNDI
                     FLPTVGQVFNSIKEIMLNSSFYIDILYSMGRCFFSFLLAMIFAIILSIVSYLNRFFRN
                     LLKPINALTRSIPTMILVVLALIWFEKDSTPFIVGFTIVFPILYDNVLGAILNIDKNL
                     LEMANVYKIRFIDKVLKIYLPAIKFQIISILVSTFSLSLKVAIAGEVYSQPTYGIGTM
                     IQTEKINFNTSGIFAWIIIVLLISAILQIAQKFLARRAFLWKR"
     gene            7704..8402
                     /locus_tag="PC512_001390"
     CDS             7704..8402
                     /locus_tag="PC512_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2441146.1"
                     /translation="MEKIKLSIENINKRYDSRIIFRDFNIDFYVNEVNCILGKSGCGK
                     TTLLNIISGIIKNDTNNLNIKENLNRVGNKLEASYIFQDDRLIDWLTVEENIKIVVNK
                     YYNKTQLNKICDEYLELVGISDYKKFYPQMLSGGIRQRVNIARAFIYPSKNIIMDEPF
                     KSIDAKNTQLIMDNFRNILRKEKRTVLFVTHNIEEALFLADRIFILGDSPIRIKKILK
                     NSKELEKNEVLKLI"
     gene            8525..8998
                     /gene="ybaK"
                     /locus_tag="PC512_001391"
     CDS             8525..8998
                     /gene="ybaK"
                     /locus_tag="PC512_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HDF2441147.1"
                     /translation="MVKTNAMRILDSNKIDYKVMSYEVKSEHVDGVEVAHDIGRDVNE
                     VYKTLVTQGVSKNIYVYVIPVHENLDLKKAAKVAKEKSVEMIHVKDINKLTGYIRGGC
                     SPIGMKKLYKTFVNESAKNLDTIIVSAGKIGYQIELSPFDLQRLIKVEFVDVIKK"
     gene            9195..10034
                     /locus_tag="PC512_001392"
     CDS             9195..10034
                     /locus_tag="PC512_001392"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate hydratase"
                     /protein_id="HDF2441148.1"
                     /translation="MRKIKSEQIVEQVKKLCIEASLYLGEDVLSCIKEKAKSEKSEVG
                     KNILNILVENAEIAKEKNIPICQDTGMAVFFVEIGQEVLIEGDTLTDAINEGVRQGYE
                     EGYLRKSVVSPINRVNTKDNTPAVIHYDMVKGDKIKIEFAAKGFGSENMSKMKMLKPS
                     DGLEGIKKFIIDTVSEAGPNPCPPMVIGVGIGGTVDKCAQIAKKALFRELGEFNKDEN
                     IAKLESELLTAINKLGIGPQGLGGTTTALGLNIETFPTHIAGLPVVVNINCHASRHKK
                     VVI"
     gene            10047..10595
                     /locus_tag="PC512_001393"
     CDS             10047..10595
                     /locus_tag="PC512_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S-containing hydro-lyase"
                     /protein_id="HDF2441149.1"
                     /translation="MIKITTPVNEIDIAKLNCGDTISLSGILYTARDAAHKRLIDCIN
                     KGEELPFDVYGQGIYYVGPTPTKPGEVIGAAGPTTSYRMDDLTIPLLERGLRLMIGKG
                     KRSDEVIEGMQKYGAVYLAAIGGAGAYISNSIKSCEIIAYEDLGAEAIRKIVVEDLKL
                     TVAIDSYGNNIYEQGRAIYECK"
     gene            10661..11842
                     /locus_tag="PC512_001394"
     CDS             10661..11842
                     /locus_tag="PC512_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent malic enzyme"
                     /protein_id="HDF2441150.1"
                     /translation="MSKDYAKLALEMHEINKGKVSVESKVEVKTKDDLSTAYTPGVAE
                     PCLKIHENQDDVYRYTSKGNLVAVVSDGSAVLGLGNIGAEASIPVMEGKAILFKQFAD
                     VDAFPICLKTNDVDEIVKSVELMEPVFGGINLEDISSPRCFEIEERLKKSLSIPVFHD
                     DQHGTAIIVAAAIINSIKLIENKKIEDLEIVINGAGAAGIAIAKILLNMNVKNIILCD
                     RSGALEASIENLNYVQKEMLKVTNIRNEKGPLKDIIKGKDVFIGVSGPGAVTKEMVES
                     MSEKPIILAMANPAPEIMPEEAKLGGAFIMGTGRSDFPNQVNNVLAFPGIFRGALDVK
                     AKEINEEMKIAAAYAIANTISDEEICPEYILPDVFNKNVVKNVAKAVKEAAIKTKVNR
                     I"
     gene            12010..12396
                     /locus_tag="PC512_001395"
     CDS             12010..12396
                     /locus_tag="PC512_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009248914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2441151.1"
                     /translation="MEYKVNDQELNASMFIPFVNRIWPGDYDTDKTQTALSKTLNITA
                     YDDKVLVGCLRVLSDGYYFGTITELLVLPEYQKQGIGSKLFQLAKENTPTMLYFGAQP
                     GVEEFYEKNGCQRSLQSYIIKKKDSY"
     gene            12546..12809
                     /locus_tag="PC512_001396"
     CDS             12546..12809
                     /locus_tag="PC512_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HDF2441152.1"
                     /translation="MEETKFCQCCAMPMGQTDELYGTNKDGSKSTDYCSYCFKDGEFT
                     ADISMEEMIEVCIPHMLQSNKDMTEDEARTMMNNFFPTLKRWK"
     gene            13335..14018
                     /locus_tag="PC512_001397"
     CDS             13335..14018
                     /locus_tag="PC512_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2441153.1"
                     /translation="MSSILLVEDDLSLIYGLEFSIQKSGFSIDIARTVKEAMQMYEEK
                     NYDLLLLDVSLPDGNGFQICEKVREVSNIPIIFLTASDEEVNVVMGLDMGGDDYITKP
                     FKLNELISRIKALLRRYNVASNVNELSSNNITIKLLENRVFKGKFEVELTTAEYKLLC
                     LFMKNKNIVLTRKNILDKLWDGNGSFIDDNTLSVYVRRLRNKIEDNPENPKFLLTVRR
                     MGYKWNVIK"
     gene            14029..15270
                     /locus_tag="PC512_001398"
     CDS             14029..15270
                     /locus_tag="PC512_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2441154.1"
                     /translation="MKIFSNKDIKIFFLMLISILVMFIIVGQIVVISITNNYKKTLIE
                     HDYNIAGYLYSIGVDKSKIPSAFVAHEDKYILKGKEILDTAGYGFDIDVSFTPSVKLF
                     QSKYIKTMSIYLLVFFTMIIFILYMYFFRQQSKIEEASYKIDLFMNGNINERLNTYEE
                     GSLSKLFSSIDVMSTSLNTHILKEKQSREFLKNTISDISHQLKTPLTALIMYNQILQE
                     ESHNSDVVEAFVQKSQSELERIETLIKNLLKITKIDSKTIILNKNNVNLKNLIVKILY
                     SFETRAEKEGKVISVNGSENTLLFCDYEWMSEALSNLIKNALDNTKENDKITIEWFET
                     TITTIVSVKDTGNGIHVEDIHHIFKRFYRSKFSKDNQGLGLGLPLVKSIVEQHNGTIS
                     VESKLSQGSIFTISFLKLTNM"
     gene            15342..16025
                     /locus_tag="PC512_001399"
     CDS             15342..16025
                     /locus_tag="PC512_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002574824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2441155.1"
                     /translation="MDILVVNNLCKTYGNGYTKVEALKDVSFTVSKGEFVTVVGESGS
                     GKSTLLNLLGGLDTPTSGRIFIDGKEICSMKEEKQTIFRRRNIGFIFQAYNLIPELTV
                     EQNIIFPLLLDYKKPDTIYLDEVLTILGLKDRKNHLPNQLSGGQQQRVAIGRALITKP
                     SIILADEPTGNLDSKNSNDVISLLKVTAEKYNQTIIMITHNTNIASTADRILQVSDGV
                     LTDLGVNRE"
     gene            16022..18352
                     /locus_tag="PC512_001400"
     CDS             16022..18352
                     /locus_tag="PC512_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2441156.1"
                     /translation="MRSYLELVPQYAKVHKKKNRTTILCIIIAVCLVTAIFGLADMAI
                     QCQKIQFIKDDGNWHIVIRNIDEKFISEINSRVDIAHHGRGQVVDNGEFKSKEILIQG
                     LDEEVAKQFNLEIIRGRYPIGENETLIDEDAVKSFNLKIGDFIKIKLADGRNKNYKIV
                     GEYSSISSLRATDKHGLILSILGTQAIKKSETYDYYYITFKEKVNIRKATSDIKNTFN
                     LSDKQIGKNERLLSIIGQGDSDFSKPLYLTAGLLFVLVLVASIIMIYNSFNMSVIERV
                     KFFGLLRCLGSSKHQVKKFVVLESLILSIKAIPIGLVLGSLVTIISSIFLKYVNELFS
                     SMPILKVSFIGIAFGIIVGFLTVILSAIIPAKKASRVSPLSAVRGNLMSKEILNNGKT
                     SKVANIGSFKIETSMGLNHAFSRKKSFVLMTSSFAISIILFLGFSVLIDLMYQGLKPM
                     KPEAPHISIVDPNFKSVLTKEDINEISNIKGVKKVYSRMMTDIEATYNGKKTKSQLIS
                     YEKYQFNWAKKYLLKGEVNENKLQSENLALVEEGHGFDIGDKIYIKNGNAEKELEVGG
                     ILSSIPFEAKDKYIGNIITSENTFTNITGIKGYIIMDIQVDKDTPGDLIENIRRVVDD
                     NLEVRDKRQSNLEVKNSFYTMATFVYGFVFIIAIISMFNIINSMNISVTSRKNYYGVM
                     RAVGISNRQLRRMVIVEAGSYAVSGCLLGSILGLILHRYMFISLVSSMFHLEWQVPFN
                     LLLITVLTMIIITLLSVRKPIKKICELDIIDSINAQ"
     gene            complement(18533..19375)
                     /locus_tag="PC512_001401"
     CDS             complement(18533..19375)
                     /locus_tag="PC512_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDF2441157.1"
                     /translation="MINIGDFNKLTVKRKTEFGYFLDGQTNNTKDDILLHNRLIGKNE
                     INIGDEVNAFIFKDSDDRTAATLIPPLAKVGDVAHLKVVDNTDIGTFIDMGLPKDILV
                     PFKAKTYPLFRDEKYLFYIYLDKSKRIAATTDIDSYLLTDHTYNVGDIVTGVVYGFQT
                     NNSAMICVDNKYAGVILHNEYFTELKTGDVLENLHVIKIYEDGKLGLSPRGNRKDELD
                     TLENKILSYLEGSDGYMRFNDKSDPKDISILFNSSKKNFKRALGVLMKKGLIYQDEEG
                     TYLK"
     gene            19670..20404
                     /locus_tag="PC512_001402"
     CDS             19670..20404
                     /locus_tag="PC512_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2441158.1"
                     /translation="MKIVNKSSNIPLHTQLSSIIREMIETGELKEGDAIMPERELCNI
                     QNVSRMTVNKTIVGLVTEGLLYRVQGKGTFVAKQKKKYQFSNVKGFTDVMKEKGVNIK
                     TDILSFEMELPDDLVKRKLGISDNTTNIYKIVRLRYTDGEPFGLEIVYLSEEMCKGLT
                     KGILDNSSLYRVLNEKYGYKIQKAEQVMEPVILSDEESKLLETDEGALALKLHRNSYN
                     REGRPIEYTISIFRTDKYQYEIVLSE"
     gene            20414..21547
                     /gene="nagA"
                     /locus_tag="PC512_001403"
     CDS             20414..21547
                     /gene="nagA"
                     /locus_tag="PC512_001403"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HDF2441159.1"
                     /translation="MKCLINGKIILKNQILENKVLVFDEKIIDIADSVPKDCEVIDAD
                     GKYISPGLIDIHIHGNMGKDTMDSTDESIETISKSIMRHGVTSFLPTTMTMDKEHVYD
                     ALEVIKKAQNRKLEGAQVLGAHLEGPFINENYKGAQNEKFIINSKYEFIKEYKDVIKV
                     ITYAPEKDIDFDFTREIKRCTDIVLSIGHSNANYDQAKEAINLGVTNVTHMFNAMTGL
                     NHRDPGVVGAALTTNVYSELIADTIHINKDLFQFILNNKGKERLILITDSIEAGGLED
                     GNYSLGGQKVIVKGNEARLENGALAGSVLSLNKMVFNFLNNTNLKVNEAINLASLNPA
                     TSLGINDKKGSLEIGKDADIAVFDENLDCKMTLCLGEVVYKNI"
     gene            21646..22395
                     /gene="nagB"
                     /locus_tag="PC512_001404"
     CDS             21646..22395
                     /gene="nagB"
                     /locus_tag="PC512_001404"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012425552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HDF2441160.1"
                     /translation="MRVLVCKDYDGMSKKAAEMIAAQIVLKPNSILGLATGSTPVGMY
                     RDLVKKYNDNIVDFSDVMSFNLDEYYKLPISNDQSYDYFMKENLFNHVNIKPENTHLP
                     NGMADDIEKECMNYEASIDAAGGIDVQVLGIGRNAHIGFNEPDTKFAKRTHVVELTES
                     TIEANARFFKSREDVPKKAVSMGIGSILKSKKILLLASGEEKADAVYNTVYGDITPEV
                     PGSILQLHKDTIVIVDEAAASKLNPKDYKLV"
     gene            22547..22819
                     /locus_tag="PC512_001405"
     CDS             22547..22819
                     /locus_tag="PC512_001405"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441161.1"
                     /translation="MLKIIMFSGILSSIIKLPIIGILPTGNIKKNTGISDSKKDGKQR
                     RSNLGISIYQLPSFLYSLINNSVPSNKPIPPEEIKLIKMYLLKSCI"
     gene            23479..24183
                     /locus_tag="PC512_001406"
     CDS             23479..24183
                     /locus_tag="PC512_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2441162.1"
                     /translation="MSKLIYIADDEDNIRNLVKTFLKNEGHDVMDFKTGDELLEQFNI
                     KECDLVILDIMMPGSSGFEVCTKLREKSTVPIIMLTARDTDIDYITGITLGSDDYFTK
                     PFSPMSLVMRVKSIFRRIEFEKKQNYDKYSNSIDMELKFGDVIINKKNKIVTSKNVNI
                     DLTPNEYNLLTYLFENIDRAISRDELLNKIWGYDIEVETRAADDTVKRLRKKILDTNI
                     LIETVWGFGFRLKEKS"
     gene            24185..25672
                     /locus_tag="PC512_001407"
     CDS             24185..25672
                     /locus_tag="PC512_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2441163.1"
                     /translation="MKNGNDKNRIGKIKSKFKLKFSKKNISIKTRILLSILCLIIIVF
                     MIILVSFNVFLDTYIKTTANEELTKSTEIVEHMDSNFRPIKPPQDDGKLPPKVLSNFM
                     RNVQDKVRMAETQSDADAMVVDSKYNLIFPTREDDFLKNVDEMELIRECIQNEKLDLN
                     SDANTRISTRNKDYYISTVKITSIYGEQDKYLILFIDISKTLNLAQKINIVLISVMCF
                     AGILAIFTAVILSEKIAKPIKELCEFAKKMGQGDFKRTYFDFSDKELVELSTVMNKSA
                     EYLDKYDNEQKIFFQNASHELRTPLMSIKGYAEAIKYNVIDSKHASDIILEESDRLSD
                     MVEDLLYISKIDNITKDFELVECDLREVLSNCGARQNVRAINKGIKFIYEFDEEMVLF
                     ECDEKNISKAFMNLIENALRYAKSEIKIVCKYNQKNIVVIIEDDGIGIKKEDLPHVFE
                     RFYKGVGGNHGIGLSIVKSIVNKHGGRIYVENGKKGAKFTILFKL"
     gene            25877..27490
                     /locus_tag="PC512_001408"
     CDS             25877..27490
                     /locus_tag="PC512_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDF2441164.1"
                     /translation="MKEQLIFNITNLVTVVFEAFVIHMFLSDFLGQKEGYIKVVRYAK
                     LGFIICLGFCNLITLNPKITMPLIFILIFSTSFLYKGNLKTRLFTTVLLSIFFILSEI
                     VVTSIFVLFVKEGFEIMLENNSIRVLATILSKIVFLLTCKIICLFKKDVHLDMPIKYW
                     LPLFLIPIFSLFLSVSIFDVSKFFSLESLKFLSLISSVGILYINFIVFYLFKFIIDKT
                     KLSMKYELLEKEIIHKEELRLSNECYKIIVEQTDSVVFEWNIKENKSFVSQAWTEKFG
                     YNNACKNIFKEIKDKDLVHSEDKAIFEGFLESIKKKNMHNQAVYRLKKSNGEYIWCRT
                     SITSIYNDENELLRVVGVIVDVDSDIKKYEELRTRAESDSLTNIYNKGTFEKLVEETI
                     VMNTGDKKDALFIIDLDDFKEINDNFGHPFGDFVLKTFADKIQTSFGSKDLVGRIGGD
                     EFVVYMQDYVTEVNLHKKAKELNRVLSDNYTDLSFSFDASVSIGIARYPQDGTSFFEL
                     FKNADRALYSIKASGKNSYCLFEEELYVQ"
     gene            complement(27853..28683)
                     /locus_tag="PC512_001409"
     CDS             complement(27853..28683)
                     /locus_tag="PC512_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2441165.1"
                     /translation="MSQVSKNYFTTGEFAKICGINKKTLFHYDDIGLFSPELKKENGY
                     RYYSYHQLSIFGIISSLREVKMPLKEIKAYIDKRTPNLLIELLEKKTIDIKNEIEKLN
                     NIQALMESTISFTKNACNIDANTITLKEHEEEYLVKTPVTYKEQFLGDEEENFLYECI
                     NFMDNYELSDYGTIGSIIKGEDIINKDFESYSYLFTKVNKEYKKYPVSIKPKGLYVTA
                     YHKGSYETIYKAYEKLLNFFNQNNLRIGDFVYEEYLLYDISVRDSNEYLTQISAEVKM
                     "
     gene            28756..30483
                     /locus_tag="PC512_001410"
     CDS             28756..30483
                     /locus_tag="PC512_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2441166.1"
                     /translation="MKKLIHFLKPYRVLIVVVLIFTFLQTLGTLYIPTLTANIVNNGV
                     VKGDIDYIVKTGLMMMIVAGITALSAVLVCKVSANLSSGFCRDIREAVFIKSQDLSIN
                     DFNNIGTASMITRSTSDITLIGQSVFMFIQLVLPAPIITVSGLFLAYSIDKAMTIIIV
                     VVMFLFMLSAFLVGKKLIKLFKMMQIKMDNMNRVLREVVTGVRVIRAFNRSHFEKKRF
                     DRTAIDYSETAISINKIFAVLMPIVMLIMNLGIVSIIWFGGMRVSNGNMEIGHIMALV
                     EYCILILFYLIMGVMVFMYIPRAGACADRVNQILDIEPEIVDGNGHKDTVSERGHLVF
                     KNVTFSYAQSEEPVLNNITFEAKSGEVTAIIGSTGSGKSTIANIIPRFFEIQSGEISI
                     NGQDIKKIPQKELRDKIGFVPQKAFLFSGTIEENIRYGKEDASIEEVKHAASIAQADE
                     FISDMEDKYDSFVAQGGNNLSGGQKQRISIARALVRKPEVYVFDDSFSALDFKTDKRL
                     RKALKNEIKDSSAIIIAQRISTIMDANQIIVLNDGKIVGIGKHKDLLENCEVYKQIAD
                     SQLSKEELA"
     gene            30520..32382
                     /locus_tag="PC512_001411"
     CDS             30520..32382
                     /locus_tag="PC512_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2441167.1"
                     /translation="MSEKRIDEQDIEVLSFEDGMSAEKAKDAKKTTKRLLKYMAKQKF
                     KILIIFISVLISSALTVLAPMVMGKAIDQLFNGIKTAVQTGTKFSVNFSTMGGIVSIL
                     LGLYLISAVFIYIQQYIMSGVAQNLVLSMRKDLSDKLNKLPLKYYDSHKKGETLSIVT
                     NDLEKVADSLQEGLMQLITAVVTVVGSIVMMISISVPLTIVSAITLLVSLGITVVIAR
                     KSQERFSENQKALGELNSNIEEIFTGQIVVKAFSKEKDTIRNFKILNQNLYNASRKAQ
                     FSSYAISPIIRFINLIGYVIIAVVGGIFASTGAMTLGSIQAFIQYVNQASEPTTEISY
                     IVNMLQAAIASAERVFTVMDEVEEIKDEESSKVISMPKGKVQFEHVKFGYSDDFILMK
                     DININLNAGDKIAIVGPTGAGKTTLVNLLMRFYEIQGGRITIDGVNIKDLKRGELRTM
                     FGMVLQDTWLFNGSIKENIAYSKSDATMDEIVRAAKSARVDHFIRTLPQGYDTILTED
                     ASNLSQGQKQLLTIARAILSDPSVLILDEATSSVDTRTEVEIQKAMNNLMKGRTSFVI
                     AHRLSTIRDADLILVMKEGTIIEQGSHKELIEKKGFYEELYNSQFTSEYDEDVV"
     gene            32715..33404
                     /locus_tag="PC512_001412"
     CDS             32715..33404
                     /locus_tag="PC512_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate polymerase domain-containing
                     protein"
                     /protein_id="HDF2441168.1"
                     /translation="MNKKLNYRFEMKHKITEADVLALKSRLYQIMKKDENASKDGKYL
                     IRSLYFDTPEDKALLDKLNGVAIREKFRIRFYNNDCSYIRLEKKIKHYNMTSKLSTNL
                     TKKEVINILNNDIEFLKESTNCLLREFYLKLKCERLEAKSIVDYNREAFIYPVGNVRV
                     TIDSDIKTSVNSVDLFNKDLPTVSVIDENMTVLEVKYDEFIPDFIKDLIQINKTTSTA
                     VSKYASSRLYI"
     gene            33509..34195
                     /locus_tag="PC512_001413"
     CDS             33509..34195
                     /locus_tag="PC512_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4956 domain-containing protein"
                     /protein_id="HDF2441169.1"
                     /translation="MILIMTFNDIFKSSFIENVSGFSFVDSALALGSAFLVGLFIYMV
                     YKKTYMGIMYSRPFNVSLVALTMLTTFVILAVTSNVVLSLGMVGALSIVRFRTAIKDP
                     MDLVFLFWSLGSGIVLGAGLIPLAVMGSIIMGLILIFFSNKTISETPYILMVNCNNED
                     SEDIATDKIKKVFTKYQIKSKSVTPEKGIELVFEVRMKDGETSLINDLSQVDGVTNAV
                     LVSYNGDYVA"
     gene            34212..36119
                     /locus_tag="PC512_001414"
     CDS             34212..36119
                     /locus_tag="PC512_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CotH kinase family protein"
                     /protein_id="HDF2441170.1"
                     /translation="MKDKKFTLLISIMIIFLCAVVGVYSTSSNKSVDLYSDVYIEKYF
                     NRDKVMEVNIEIDESDLKDMNENAIKEEFKVAKVTVDGDTYGNVGIRTKGNSSLISVA
                     NSDSDRYSYKINFDKYNTSQSMEGLTQLNLNNCYSDPSYMREFLTYSICEEMGLATPE
                     FAYAKVSINGEYHGLYLAVEGLKESYLENNFGNVTGDLYKSDEGSSLQYKGDDPESYS
                     NLIVESDKKTADWSKITKLLKSLDTGEDIEKYLDVDSVLKNIAINTALLNLDSYQGSF
                     AHNYYLYEQDGVFSMLPWDFNMSFGGFSGFGGGSQSIAIDEPTTGNLEDRPLISSLLK
                     NETYKTKYHKYLEEIVTKYLDSDYLENMTTKLHDMIASYVKEDPTAFYTYEEFEKNIT
                     SSIEDSSDNKGFGNKGFDNNNSNNSDSNNNSNSENKRSGNQSDEKEVNAELTSSVVKA
                     NTDNETKNKTTNDSESKNNTDKDKSGNDNNQKLEGPMGKGGKSIPGVLEVAEDMSKTI
                     KSQLSGETSSTKQNSGDESSSGIKGSEKFDEDMSGMPEPPEGMDGKMPPGMGNMDKGD
                     MNGKNGNMNMDRNQDNPIEVGGFGNRGGGSVSKTTTYFKLILGGASMIIMSIMLVGVS
                     RVKRRRFIKSK"
     gene            36570..37259
                     /locus_tag="PC512_001415"
     CDS             36570..37259
                     /locus_tag="PC512_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441171.1"
                     /translation="MLQKVLWKFLKLVVGLFICSVGIVLTINCNLGLSPWDVFHQGLS
                     NHIGITIGTASIIVGSIVVIADVVLGENVGWGTVFNMLLIGFFMDLLLYSNLIPEADN
                     LFVGIIMLILGLVLLSVGMVFYMGSGLGSGPRDGLMVAIQKKTGKSLKLIRGTIEVGA
                     LIVGFLLGGKVGIGTIISAFGLGYFTQMVFGLFKLDCSKIKHRFIVDDIKFIKVYMSG
                     EKKAAVQNIVK"
     gene            37695..38234
                     /locus_tag="PC512_001416"
     CDS             37695..38234
                     /locus_tag="PC512_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007286148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2441172.1"
                     /translation="MDIGEKIKRLRTEKQLTQEELANRCELSKGFISQLENNLTSPSI
                     ATLIDILEILGTNLREFFNEIDDERISFTKEDMFETEDEDLKYKLKWLIPNSQKNEME
                     PIIITLYPGGQYKEEKPHEGEEFGYVLAGSIYVHIGEKKNKVKKGESFYFRPKANHYI
                     SNEGKTTAKVIWVSTPPSF"
     gene            38253..39296
                     /locus_tag="PC512_001417"
     CDS             38253..39296
                     /locus_tag="PC512_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2441173.1"
                     /translation="MVENIIELRDISKHYEELTVLDNFNLDIKKNEFLTLLGPSGCGK
                     TTTLKIIAGFEYADDGKVLFEGKEINNLPPYERQVNTVFQKYALFPHMDVYENVAFGL
                     KIKKTPKDVIDAKVKEVLKLVALEGFERRQVESLSGGQQQRIAIARALVNEPKVLLLD
                     EPLGALDLKLRQEMQIELKRIQKKLGITFVFVTHDQEEALTMSDTIVVMYKGKIQQMG
                     TPQDIYNEPKNSFVAKFIGESNIFDGIMIEDYKVNFCNRDFECVDKGFEKNENIEVVI
                     RPEDIKMVKPEEGMLKGKVTSTVFKGVHYEIELNENGRLWILHNTKNAEVGTELGMDI
                     YPEDIHIMRKENN"
     gene            39298..40134
                     /locus_tag="PC512_001418"
     CDS             39298..40134
                     /locus_tag="PC512_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2441174.1"
                     /translation="MKRKSFLAYPYVVWSAIFVIIPLILVVFFSFTKESGGGYAFTLE
                     NYKEVIDPIYMKVFGRSILLAGGATLICLIVGYPVAYIISKARVSRRGSLILLFILPM
                     WMNFLLRTYAWVAILGKNGLLNTFLGWFGIQPLAILYTNFAILLGMVYNFLPFMVLPI
                     YTALSKMDNDLINAAHDLGANNMTVFRKIIFPLSLPGVMSGITMVFMPAVTTFAISRL
                     LGGGKIMLVGDLIEQQFTVVGDWNFGSAISIFMMIVILISMSIMSKFGDESDKEGGGL
                     LF"
     gene            40239..40913
                     /locus_tag="PC512_001419"
     CDS             40239..40913
                     /locus_tag="PC512_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2441175.1"
                     /translation="MARWNGFTWKWYGQLLQNESIMSALYYTIVIAILASVISTIVGT
                     ISAIGIHKMRGKSKKLILNVNYLPILNTEIVTAVALMSLFVFVKMEFGFTTMLLAHIM
                     FCLPYVILSVLPKMKQLPDNIEDAAMDLGATPIYALRKVILPQIKPGIVSGFLIAFTM
                     SIDDFIISFFNAGNGVSNLSIEIYGMARRGIKPEINALSTIMFAVVLGLLLLANKKES
                     IVRGIK"
     gene            40913..41965
                     /locus_tag="PC512_001420"
     CDS             40913..41965
                     /locus_tag="PC512_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF2441176.1"
                     /translation="MIKFKKAISLIAVGMMTVTLFTGCNKATDSTKVLNVYNVGDYID
                     ESLIDKFEKETGIDVQYSTYDTNEMMYQKVKSGSTHYDLVFPSDYMVEKMKNEGLLEK
                     LDFKNIPNMKYLDKSFLNPVYDKTNEYSVAYMWGTLGILYNKKEVKDPMDSWNILWNP
                     KYKGNIMMFDSVRDTIGITLKKLGYSMNSVNPKEINEAKNLLMKQKDLVLAYVNDEGK
                     DRLLGGEVAMGMLYSGDAVTLMEQNPDLDYAIPKEGTNKWVDAMCVPTTAQNKKEAEL
                     FINFLLDPENAKVNAEYIGYSTPNTGALKLLDPEITQNPVAYPSKEVLDKCETFEDIG
                     ENIKLYDKAWIELKSK"
     gene            42195..43043
                     /locus_tag="PC512_001421"
     CDS             42195..43043
                     /locus_tag="PC512_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF2441177.1"
                     /translation="MNRINKKIDLLILALLVFIFLIVGIVILSIRTENKLNVFIMLAI
                     IFFIIMLTYLSNSVVGLITSSIIIFMYTSYILYNNITHNMDVEFISYMWIIATPVSSI
                     IMGNLNKSINELQNTNKKLSEQYKELVTIDSETGLRNLKIFYNDVNMEISKSIRHNTD
                     FSLMIVKLPYYGNLQTIFGENKTNKIVKYIGSNIIECTRNEDIIYSLQKDMIGILMPN
                     TSLEGSKVVKDRIKKRIKELNLDLNNRGKYVNIDVKIAFLQYKSSFGDSINFKNIVEE
                     ELQYDV"
     gene            43033..44697
                     /locus_tag="PC512_001422"
     CDS             43033..44697
                     /locus_tag="PC512_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDF2441178.1"
                     /translation="MMFKIFNKSLLKLVVVLSIVLTISNFSLSSYASEITSSTDKVLI
                     IYDSKKETAYNRDILNIMRTLLGRFSSDIELLKLSNYDGEINKNYYSHIFILGINENS
                     YNNDKNTKNLISSLNSYKGTICWLGYGIENLLEHKKYNLDYVGKTNNIVSVNYRGKSY
                     NLDEHYVFNIVESKDTSNKVIGSINDTLNKYPYIINDKNLFYVSKLDLDGVLFYIFCD
                     SLNDIFNIKTFDKGRIFVRIEDVHAFREPKNLVEIADYLSSKNIPFTIALIPAYVNPK
                     NHKVITLSESPEIVKAIKYMQDKGGTVILHGYTHQYKKEEVSGEGYEFWDGKKDEPLK
                     ENMKIFVKDRVLNGLRVCIENGIYPLAFEAPHYAMESEGYKELKKYFSTYMGQHQNND
                     KKFSTNTYPYIIRDTEEFNIFIPENLGYIDPEDKFTFQNIKENLNKLSIVRGFSGGFF
                     FHSYLNIEYLKNTIEYLEKQNIEFMNLRDFNNWVKVDEIQIRNNGDEIIVNYDKDLDE
                     ITKSDTRFKSISNISKVLIFIVSISVLIFVIIFIYFKRIDKKKFLK"
     gene            44746..46002
                     /locus_tag="PC512_001423"
     CDS             44746..46002
                     /locus_tag="PC512_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003362983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDF2441179.1"
                     /translation="MRDLNVSEYLFVFSLFSIWSLLLINIILAMGGYIFYFKNFDKEI
                     KEIDEYPMISILVPAHNEAKVIGRTVESLLLLNYPKSKMELIVINDNSSDNSKEILEN
                     IKDRYNNYNFTIINTDSLTGGKGKSNALNIGYTISKGDFIAVYDADNTPDKNALRYLV
                     QTIVMNDELGAVIGKFRTRNKNKNLLTKFINIETLSFQWMSQAGRWQLFNLCTIPGTN
                     FILRRSIIEEIGGWDSKAIAEDTEISFRIYKLGYKIKLVPQSITWEQEPETVKVWIKQ
                     RTRWAKGNIYVLMKYIKNIFKQGRNKIVFDIAYFFSVYFLFLTSVIISDILFVLSISK
                     LVEISIPINFFLIWILSYLLFIIEVSISLTIEKGEATIENIFIVAIMYFTYSQLWLFV
                     AIKGMIEYLKDIIFKREVKWYKTERF"
     gene            46025..48106
                     /locus_tag="PC512_001424"
     CDS             46025..48106
                     /locus_tag="PC512_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis cyclic di-GMP-binding
                     regulatory protein BcsB"
                     /protein_id="HDF2441180.1"
                     /translation="MKKFIISIISLVLFFSNISLIYKVNADETKVKNYKFERDITIDG
                     VIGSNSTFFEVNKNWDIEEVLLHLNFSKSQILNGDVSSLTVLINNVPIKSIKLNAKTN
                     YKNTLEVLVPKDYIIQGYNEIKIKTYKTISDKICQDDSNTGNWMVIHKESYISIRYKQ
                     KKVENSINEYPYPYAEIENNHKLDTTIVVPDNMTRGETTAVFNLASAFGKITKNDDLK
                     LDVKLYSEMKNWSDDNIIYIGKPENTAEEILDILSIKEQTLLSSNCIIKQVDSPYNKN
                     KKMMVVIGSNEDDLIKASNLLIENRLSNQVLSSSVLVNKETNIKINREQKLNLGHLTL
                     KDLGYSDFLLEGAFNQQALFDVKIPTGKVLDDGSKIILNLRYSDNLDFEKSLVTVSIN
                     DVIVGSKKLDRSHSNNDKLELKIPKDIDNKNYYQVKLTFNLSIKNSNCVTRESNNPWA
                     YVSNNSYLALSMKENETLSFENYPYPFVRDDEFNDLTVIMPDYSGSQAMTWMFRLGVT
                     LGANINSHNGNINVIRGKEFSDKYKDTNIVVFGVPHNNSVIKMLNNNLNIKFDKNYSN
                     FISNDKISFIDDYGKNISTIQLIKSPYNNQKNIMVISSMNEKNLYLGMDYLLNKSKVN
                     DLKGDTLIIDEYGEVEDLAYNLKSKKEVKDSSWNMSINKTTKVFLMISFITIIVVMIL
                     SMLYIKKYKRR"
BASE COUNT        19107 a         4911 c         8313 g        15787 t
ORIGIN      
        1 ttaatattaa ttaagaatga tgaaatatga ataaagattt tacaaataaa tcttaagcta
       61 tcttatttaa ttctaataca ggaagaaggt aaatgtatat tgaaaaaatc atagaaatag
      121 aagtaaacaa tttaaataaa tacaaaggtt tgcaaaagaa gtaatataat tatatacaat
      181 gaggatgtga gtatgatgaa cagactaaag ccaagaattt taggtattag tatcttgttt
      241 attattataa ttattttaac atgtggagct gttttcaagt ttaaatttaa attagataat
      301 aaattaaaag aaaccacaca tacatatttg tctgagttta cagaacacaa tataattaat
      361 ctcaagacaa gacttagtgg tcaatttgac atgcttgaat ctattgctaa cttcatagga
      421 aacttgaata atataaatga tgaaatggtg attgatttaa tggattctga tgtaaagcga
      481 agttctttaa ttagaatgac tatctctaca ttagatgggg aatgttattc taatgatgga
      541 attacccata atgttcaaga tagagattat tttaaaaaag ctaaaaatgg agaaaagaat
      601 atatcagagc ctttaaaatc tattgttaat aataaagaaa taatagtttt atctacccca
      661 gtttataaaa gtgggaaaat agttggtgtt ttaagtggaa tttatgattc aaaaaagtta
      721 aatgaattat taggattatc tgcatttgat gaaaaagcag atgtttttgt tgcaaagaaa
      781 aatggagata taattgctca aaaaacaaat aaaaatagta agacgatatc atgtatattt
      841 cagctttttg acaaagataa ttgtgatgaa gttgattgtc taaaaactat aaaagaaaat
      901 atgaaaaatg ataagtctga gtattttaat tataacttag ataatgaaaa atttatgtta
      961 aactatcagc cacttggagt taatgattgg tatgtttttt ctgttgtgcc aaataaaata
     1021 gtgtctattc agtcagagaa tatatcttat gatgtatata tttttgcatg aaatactact
     1081 agttatatta atttttataa tatatatagc atgtattata aataataaca ccaaaattat
     1141 tataaatgaa aaagaaaaat ttaaagtact cactgataat atactaggag gggttaaaac
     1201 ctgtttaaaa gatgaatata tgactatgac atatgtaagt caggggtttt tagagcttac
     1261 aggttactct tgtgaagatt taaataaaat atttaaaaat agatttaaag acatgattta
     1321 taaagatgat ttagacaagt ttaattgtat tattctaaac caattagaaa aacaagataa
     1381 aattgaagtt gaatatagaa ttgtaagaaa agatggaagt ataatttgga ttttggagag
     1441 aagtaagtct ataaatgata ataaaggaag tgagtgtatt cagggagttt taactgatat
     1501 aacagaattt aagaaaatac aagaagagtt agattcaaaa agatttgaaa tacaggctat
     1561 caatgatagt attgttggtg gaatagtgat aactgagata aatgatgatt ttgatagtat
     1621 atatttaaat gaaggttatt taaatatgat tggatataca cgcaaacaac tgaaagatga
     1681 gctaaataat aaattaatca aacttatttt taaagatgat agaacagaat taattaatag
     1741 tataaacaaa caactcaaat taagtgatac atttgcatct gaacaaagag ttgaaaaaag
     1801 ggatggcact attatatgga ttttattaaa aggaagaaag atgatttatg ataatggaaa
     1861 atctgtactt tgttgtgtta ttgtagatat tacttctgct aaattattag agcaagaact
     1921 taaaaagagt gaagaacgtc atgaaatcat tctaaagcag acgcaaaata ttataataga
     1981 atgggatata gaaaaagata aaatgaatat atcacctaat tggtataata agtttaaata
     2041 tgaccctata actgaaaacg caacaaaaaa tataattaaa tcagtagata tatatcatga
     2101 tgatatggat aagtttattt cattaattaa acttacttca caaggtagtg agtatgaaga
     2161 gtgtgaaatt agacttagaa ctagagatac tatttacgct tggtttagta taaaggcaac
     2221 aactttattt gataataatg gtaaacctta taaagtagta ggaagtttga ctgatattga
     2281 tgaatcaaaa cgagaagctg aaaagttgaa agaaagggca gaaaaagacc ctcttacaga
     2341 tttgtataat aaaaaagcat cacaatcact tatagaagag tacataacat tggataaaaa
     2401 aagaaaaggt gctttaatga ttattgatat tgatgacttt aaaggaataa atgataattt
     2461 aggacattta tatggggatg ctgtattaag tgaagttgca aatgacctaa taaatctatt
     2521 tagagcaacc gatatagtag gcagaattgg tggagatgag tttattgtat ttataaaaga
     2581 tatttctaaa acaagagata ttataaataa agcagaagaa ttggtaaaaa catttgaaag
     2641 gtctttttta ggtaaaggac gaaattataa aatatcatta agtgtaggaa ttgctaagtt
     2701 tccacaagat ggtatggact atatgacact atttagaaat gcggatatag ctctttactc
     2761 agccaaaggg aagggcaaga attgttatac attgtatgat aaaaaaattg ataaagtcca
     2821 atatataact aatacaagaa atgcaggaga tagtgataat gtagagatgt cttttaaaga
     2881 acatatcaca aattatatat ttgatatact atatgaatca agtgatatag aagtggcagt
     2941 aaatttaatt ctaagtattg taggtaaaca ctttaatgtg agtcgcatgt atatatttga
     3001 aaattcagat gataatcgag tatgtaaaaa tacatttgaa tggtgtaacg aaggtataac
     3061 ctcggaaatt aataatctta aaaatatttg ttacaaggat ttaggcaact atcttttaaa
     3121 ttttaatgca gatgggttat tttattgtaa tgatattgaa aatttaggta gtgatgtgaa
     3181 aaaagtactt aagccacaag gcatacgttc aatattacaa tgtaaaattt tagagggtaa
     3241 tgaatttaga gggttcatag gatttgatga atgttcatat aatcgtatgt ggactaatga
     3301 tgaagtgaac actttgacat ttatatctaa aacgctcaat atgtttttat taaaaatgcg
     3361 tattcagagt aagctagaag agtctttaac aattcaaaaa tctgtgatgg ataatatgga
     3421 tatatgggca tatgttgttg acaggaatac ctatgaatta ctatttatca ataaaaaaat
     3481 gcttgagtca gcaccaaaca ctcatgtagg tgatttatgt tataaagcga tatggaataa
     3541 tcaagataaa ccttgtaaaa aatgccctat gatatattta aaagatggtg atgatactta
     3601 taaatcattc atgcataata aaaagtttga ggtacaggca aatataacta caactacttt
     3661 gaaatggttt gatggtaaag atgcatgttt aatatttgga agtgaaataa ctagtattga
     3721 agctgaagaa aatacttaaa atactgtgtt atatatatac ttaaaatcgc aatttgaatt
     3781 tattagactt aaaatgtcta tataaatcat ttaagttgtg gttttaagta ttttttatga
     3841 tataattaag cgttaagaac aaaattaaaa gatacttttg tataaaaaaa tatttgttaa
     3901 atatatattg agcaggtgat aatatggaaa ataagttttt accaataagc aaacaagata
     3961 tgatagatag aggatgggaa gaattagatt ttgttctagt tacaggagat gcttatgtgg
     4021 accatcatag ttttggaaca gcaataatat ctagagtttt agaaagtgct gggtataaag
     4081 ttggaataat agctcaacca gactggagaa ctacagatga ttttatgaag ctaggaaaac
     4141 ctagacttgc atttctagtt aatgcaggaa atatggattc aatggtcaat cattattctg
     4201 taagtaaaaa gcatagagaa aaggatatgt attctccagg tgggaaaatg ggttatagac
     4261 cagatagagc tactatagta tattgcaata aaataagaga agcatacagt gatgttgcaa
     4321 tagtaatagg tggaattgaa gcgagcttaa gaagatttgc acactatgat tattggagtg
     4381 ataaggttag aaagtctatg ttaatagata gtggagcaga tttattagtt tatggtatga
     4441 gtgaaaagca gattgtagaa gtagccaatg cacttaatga tggatatgac ccaaaataca
     4501 ttagacatat tgatgggaca tgctatattt cagatacatt ggaagaaata tatgataaat
     4561 atatattaat tccatcatat aaagaaattt gtgaagataa aatgaagtat gtagaagctt
     4621 ttaaaattca atatgatgag caagacccat ttagaggtaa tataattgtt caacctcatg
     4681 gaagtaagta tctggttcaa aataagccag aaaaaccact tagtagagaa gaactagatg
     4741 aagtatatgg attaccatat cagaagacat accatcctgt gtatgaaaaa tttggaggaa
     4801 taccagctat agaagaagta aaatttagta tagtaagttc aagaggctgt tttggtagtt
     4861 gttcattttg tgcaataaca tttcatcaag gtagagcagt gcaaagtaga agtgaaaaat
     4921 caattattga tgaagcaata ggaataacaa atttagatga ttttaaaggg tatatacatg
     4981 atgttggagg tccaacagct aattttagaa gaccagcatg taaaaaacaa attactaaag
     5041 gtgcttgtaa aaatagacaa tgcttatctc catcaccatg taaaaattta gatgcagacc
     5101 acagtgaata cttacattta cttagagctg taagaaaatt acctaaaata aaaaaggtgt
     5161 ttgtgcgttc tggaattaga tacgattatg taatggcaga taagaacaat aaatttctta
     5221 gagagttgat agagcatcat gtaagtggtc agttaaaggt agccccagaa catatatcag
     5281 aagaagtttt aaagtatatg caaaaaccag caggaaaaac ttatgataaa tttagacaga
     5341 aattttttgc tataaatgaa gaattaggta aaaagcagta tttgataccc tatttaatgt
     5401 ctagtcaccc tggttctacc ttaaatagcg ctatagagtt agcagagtat ttaagagata
     5461 ctcactacca accagagcag gttcaggatt tttatccaac tccagggact ctatctacaa
     5521 ccatgtttta tacaggtatt gacccgctta caatgaagcc agtttatgtt cctaaatcaa
     5581 aacgtgacaa ggcaatgcaa agggctttat tacaatatag agcacctaga aattatgatt
     5641 tggtatactc tgcgttagtt gaagcaggaa gagaagactt aattggtttt ggacatagat
     5701 gtcttataaa gccaaaaaat gaaaagcctt attttaatag aaataattct aaaaaaaatg
     5761 tatctaaagg aacaaataaa aacaaaaaaa ctaatacaaa taacagaagt aataaaaatc
     5821 aacaaaaaag ttcaactaaa aaaaagaaaa aacattaaag tataaataaa aatacttaaa
     5881 aaagaaggat tattcgataa attaacagaa attagtataa ataaatataa ttattttaat
     5941 gacgttacct ttgggaggaa gagatgaaaa agtatatttc tataatatta ttagtggtgt
     6001 tgactatggt tgttttggta ggatgttcac caggaaaaga taaccctaaa aataaggagc
     6061 tatcagttgt caaacaagta aaagtagctg ttccagatgg actaccagca gtggcaatag
     6121 ctaaacttgc aaatgaaaat ccagagatta aagaaggata tgaaacagtg tatagcattg
     6181 aaaagacacc tgaagcgatt tccactagag tgatgaaaaa agatgcagat atagctatag
     6241 ttccttcaaa catggctgca atagcgtata ataaaacttc atcatataat attgttggaa
     6301 ctgtaggaat gggttcactt tatttggtgt caacagaaaa tataaaagat tactctgatt
     6361 tagttggtaa agaagttgga tgtactggaa aaggacttac tccagacata actataaaaa
     6421 gtcttttgtt acaaaaggat ataaattatt cagatataaa atttaattat gtaaattcag
     6481 caagtgaact ggtaccatta ttggctactg gtaaagttaa aacaggtatt gttccagaac
     6541 ctgcacttag tgctttgatg tctaaaaatc cagacataaa aattataaaa agtttaaatg
     6601 actcatggaa ggaagtaagt ggttcaaaag atggttatcc tcaatctact ttaattgtaa
     6661 agtctgaatt tttaagagat aataaagatt ttgttgattc ttttgtaggt caattatcaa
     6721 atagtataga ttgggcaaac aaaaatcctg aagaattagg tgcatattct gaaaaaataa
     6781 aaatatctac tgaatcaaag ataataggaa aatctcttga aagagctaat ttgaaatata
     6841 ttccagttaa ggacatgatt aaagattata aaaattacta tgagaaatta gctaattttg
     6901 atgataagac attaggaggc aaagtaccag atgaagcaat atactttgtt gagaaataaa
     6961 aaaaataaag aacaatttat agataaaatg gaggtaacac tttcttgtgt tatcctctta
     7021 tttttatggc aaattattgc tttaaaaatt gataatgata tttttttacc aacagtaggt
     7081 caagtgttta atagtataaa agagattatg ctaaattcta gtttctatat agatatactt
     7141 tactctatgg ggagatgttt ttttagtttt ttactggcta tgatttttgc tattatactt
     7201 tcaatagtgt cttatttaaa tagatttttt agaaacttat taaagccaat caatgctttg
     7261 acacgttcaa taccaactat gatattggta gtacttgcac ttatttggtt tgaaaaggat
     7321 agtacccctt ttatagttgg atttactata gtttttccta tattgtatga taacgttttg
     7381 ggcgctatat tgaatataga caagaactta ttagaaatgg ctaatgtgta taaaataagg
     7441 tttatagata aggtgttaaa aatttattta ccagccataa aatttcaaat tatatctata
     7501 ctagtatcaa cattctcttt aagtttgaaa gttgctatag caggagaggt atatagtcaa
     7561 cctacatatg gtattggaac tatgatacag actgaaaaaa ttaactttaa cacatctgga
     7621 atatttgcat ggataattat tgttctttta atatctgcta ttttacaaat agctcaaaag
     7681 tttttagcaa ggagagcttt tttatggaaa agataaagtt gagtattgaa aatataaata
     7741 aaagatatga tagtcgtatt atatttagag attttaatat tgatttttat gtaaatgagg
     7801 taaattgtat ccttggaaaa tctggttgtg gaaaaactac actcttgaac ataataagtg
     7861 ggattattaa aaatgacacc aacaatctaa atatcaaaga aaatttaaat agagtaggaa
     7921 ataagcttga agctagttac atatttcaag atgatagact tatagactgg ttaacagtag
     7981 aagaaaatat aaagatagtt gtaaataaat actataataa aactcaatta aataaaattt
     8041 gtgatgaata cttggaattg gttggaatta gtgattataa aaaattctat cctcaaatgc
     8101 ttagtggagg tattagacaa agagtaaata ttgctagagc ttttatatat ccatcaaaaa
     8161 acattataat ggatgaacct tttaaatcta ttgatgcaaa gaatacacag cttataatgg
     8221 ataatttcag aaatatatta agaaaagaaa agagaactgt gttatttgta actcataata
     8281 ttgaggaagc attgttttta gcagatagga tatttatttt aggagactct ccaattagaa
     8341 taaaaaaaat attaaaaaat tctaaggaat tggaaaaaaa tgaagttttg aagttgatat
     8401 agagttataa taatactgtc gttttaaaat atatttggtt aaaatctata agactatatt
     8461 aaaatagtac agaatattca aaactgtgta taatgttcgt attttataaa aaggaagtga
     8521 atgtatggtt aagactaatg ctatgagaat attagattca aataagattg attataaagt
     8581 aatgtcttat gaagtgaaaa gtgaacatgt ggatggtgtt gaggtggcac atgatatagg
     8641 aagagatgta aatgaagtgt ataagacatt agtaactcaa ggagttagta agaatatata
     8701 tgtatatgta ataccagtac atgaaaactt agacttaaaa aaggctgcaa aagtagctaa
     8761 agagaaaagt gtagagatga ttcatgtaaa agatataaat aagcttacag gttatattag
     8821 aggcggatgt tctcctatag gtatgaaaaa gctttataaa acttttgtaa atgaaagtgc
     8881 aaagaattta gatacaatta ttgtgagtgc aggaaaaata ggatatcaaa tagaactatc
     8941 tccatttgat ttacaaagac ttataaaagt agaatttgta gatgtaataa aaaaataaga
     9001 attacatata aaatatagag cttatattct caataatagg tgttgtaata ttaataaaat
     9061 gaataataat tttaaaataa atattcagtt acttatgtgt aattggtata aaaatattga
     9121 gaaattttaa aaacaatggt aaagtgtaag tataatcacg aatatttttt ataaagtaat
     9181 ggagggatgt tcgcttgaga aaaataaaat ctgaacaaat cgtcgagcag gtaaaaaaac
     9241 tttgtataga agcgagccta tatttaggag aagatgtttt aagttgtata aaagaaaaag
     9301 cgaaaagcga aaagagtgaa gttggaaaaa atatattgaa tatattagtt gaaaatgctg
     9361 aaatagctaa agaaaaaaat ataccaatat gccaagatac tggtatggct gtattttttg
     9421 ttgaaatagg acaagaagtt ttaattgaag gagacacact tactgatgct ataaatgagg
     9481 gagtaagaca agggtatgaa gaaggctact taagaaaatc tgttgtaagt ccaattaaca
     9541 gagtaaatac aaaagataat acacctgctg ttattcatta tgatatggta aaaggtgata
     9601 aaattaaaat agaatttgca gctaagggat ttggaagcga aaatatgagt aagatgaaaa
     9661 tgttaaagcc atcagatgga ttggaaggaa ttaaaaaatt cataatagat acagtttcag
     9721 aagctggacc taacccatgc cctcctatgg taattggagt tggtataggt gggactgtgg
     9781 acaaatgtgc tcaaatagct aaaaaggcac tttttagaga actaggtgaa tttaataagg
     9841 acgaaaatat agcaaaactt gaaagtgaac tattaacagc tattaataaa cttggtatag
     9901 gacctcaagg cttaggtggt actacaacag ctttgggatt aaacatagag acttttccta
     9961 cacacatagc aggtctacct gttgttgtaa atataaactg ccatgcatca agacataaga
    10021 aggtagtaat ttaggaggaa aataaaatga taaaaataac tacacctgta aatgaaattg
    10081 atatagcaaa attaaattgt ggagatacaa ttagtttgag tggtatactt tatacagcaa
    10141 gagatgctgc tcataaaaga ttgatagatt gtataaataa aggtgaagaa ttaccatttg
    10201 acgtatatgg tcaaggaata tattatgtag gacctactcc tacaaagcca ggagaagtta
    10261 taggtgctgc aggtccaacg acgagttata gaatggatga tttgactata cctcttttag
    10321 aaagaggtct tagattgatg ataggcaagg gaaaaagaag tgatgaagtt atagaaggta
    10381 tgcaaaaata cggagcagtt tatcttgctg caataggagg agctggagcg tatatttcaa
    10441 attcaataaa atcatgtgaa attattgcat atgaagattt aggagctgaa gctataagaa
    10501 agattgtagt agaagacctt aagcttacag tagcaataga tagctatggg aataatatat
    10561 atgagcaagg tcgagcaatt tatgaatgta aataatgttt agaaataaat atgaatatca
    10621 aaattaaaaa tagttgtgta tattttaagg aggaaaattg atgtctaagg attatgcaaa
    10681 attggcatta gaaatgcatg aaatcaacaa agggaaagta agtgtagaaa gcaaggtaga
    10741 agttaaaact aaggatgatt tatcaacagc atatacacca ggggttgcag aaccttgttt
    10801 aaaaatacat gaaaatcaag atgatgttta tagatacact tctaaaggga atctagtagc
    10861 agtagttagt gatggaagtg ctgtacttgg attaggtaac attggtgctg aagcatctat
    10921 acctgttatg gaaggtaaag ctatattgtt taaacaattt gcagatgtag acgcttttcc
    10981 aatatgttta aagactaatg atgtagatga gatagttaaa tctgtagagt tgatggaacc
    11041 tgtatttgga ggtataaatt tggaagacat atcttctcca agatgttttg agatagaaga
    11101 gagattaaaa aaatctttaa gtatacctgt ttttcatgat gaccaacatg ggacagcaat
    11161 aatagttgca gcagccataa taaactcaat aaagttaatt gaaaataaaa aaatagaaga
    11221 tttagaaata gttataaacg gagcaggagc tgctggtata gccatagcaa agatactact
    11281 taatatgaat gttaaaaata taatcttatg tgatagaagt ggagcattgg aagctagtat
    11341 agaaaatcta aactatgttc aaaaagaaat gttaaaagta acaaatataa gaaatgaaaa
    11401 aggaccttta aaagatatta taaaaggaaa agatgtattt attggtgttt caggtccagg
    11461 agctgttaca aaggaaatgg ttgaaagtat gtctgagaag ccaataatat tggcaatggc
    11521 aaatcctgct ccagagataa tgccagaaga agcaaaatta ggtggagcat ttataatggg
    11581 aacaggtcgt tcagacttcc ctaatcaagt caataatgta ttggcttttc ctggaatatt
    11641 tagaggagca ttagatgtta aggctaaaga gataaatgaa gaaatgaaga tagctgctgc
    11701 atatgcaatt gctaatacaa taagtgatga ggaaatatgc ccagagtata tattaccaga
    11761 tgtatttaat aagaatgtag taaaaaatgt tgctaaggca gttaaagaag cagctataaa
    11821 aactaaagta aatagaatat aaatttttat atgctcatat attcttactt ttatatacat
    11881 atctttatga ttaaacgtgt tagaaaacgt agtaaattta tactatcaga ctttaccttt
    11941 attacttaaa atgatataat atgaatatta taaattaata aatttaaatt tattgaggtg
    12001 caagagataa tggaatataa agttaatgac caagaactta atgcttcaat gtttatccca
    12061 ttcgttaaca ggatatggcc aggagattat gatacggata aaacacagac tgcattatca
    12121 aaaactttga atataactgc ttatgatgat aaagtgcttg taggatgtct gcgagttctt
    12181 tcagatggtt attattttgg aacaattaca gaattgcttg ttcttccaga gtatcagaaa
    12241 caaggcattg gtagtaagct tttccagctt gctaaagaga atacaccaac tatgctatat
    12301 tttggtgcac agccaggagt agaagagttc tatgaaaaaa atggatgcca aagaagtctt
    12361 caatcttaca taataaaaaa gaaagatagt tattaaagtt ccagctttca ataatcttaa
    12421 aagtacaata ttttagtgga atcatttcat tttttattac taatatgaca taaacatgtc
    12481 atattagtat tgatatactt ttaatatggt taagagccaa agaaaaatat aaggagtgat
    12541 ttaaaatgga agaaactaaa ttttgccaat gctgtgcaat gccaatggga caaactgatg
    12601 aattatatgg gacaaataaa gatggaagta aaagtactga ttattgtagt tattgtttta
    12661 aagatggtga gtttacagct gatataagta tggaagagat gatagaagtt tgtatccctc
    12721 atatgcttca aagtaataag gatatgactg aagatgaagc aagaacaatg atgaacaatt
    12781 tctttccaac attaaaacgc tggaaataat tttatgcaaa attagttata tgcaaaacat
    12841 gaaatatggt gttgagaata aggggtggtg tgctttatag cataccacct gttttgttac
    12901 ttgctagttc aggtattctt gtatgcttaa atatgttctc atctctcttt ctattttaaa
    12961 ttgtaaaaat ctaaaatatg ttatttatat tctacttctt tatccatgtc tttttctacc
    13021 acaagtcaaa tccaactaca aaatcatcat tttcaattca ctgtttaata gaattaacag
    13081 ataaagagtt ataaaatttt ctatttttta tataaaataa tacaggtcaa gctgacttct
    13141 agctacttgg gatagtgtat atatttatga tagttatagg agtaatacca atcattagac
    13201 tgttgatttg tgtagtcttt tgtaaaaaca tttgttttaa tatattgagt ttttgaaaaa
    13261 gtaaaattat aattataata aattaagtgt aataatgtat tagaagtaaa aataattaaa
    13321 atagaggtga ttaaatgagt agtatattgt tagttgaaga tgatttaagc ttgatatatg
    13381 gattagagtt ctctatacaa aaaagtggat ttagtataga catagcaagg acagtaaaag
    13441 aagctatgca aatgtatgag gaaaaaaatt atgacttatt gcttttagat gtatccctac
    13501 ctgatggtaa tggatttcag atttgcgaaa aagtacgaga ggtttctaat atacccatta
    13561 tatttttgac tgcttcagat gaagaggtaa atgtagtgat gggtcttgat atgggtggag
    13621 acgattatat aacaaaacct tttaaattaa atgaattaat ttcaagaata aaagcattac
    13681 ttagacgtta taatgttgca agtaatgtga atgaattaag ttcaaataat attactatta
    13741 aattacttga aaatcgtgtt tttaaaggta aatttgaggt ggaacttacc acagcagaat
    13801 ataaattatt gtgcttattt atgaaaaata aaaatattgt acttactaga aaaaacatat
    13861 tggacaagtt atgggatgga aatggtagct ttatagatga caatacatta tcagtatatg
    13921 taagacgatt gagaaataaa attgaagata atcctgaaaa tcctaagttt ctattgaccg
    13981 ttagaagaat gggttataag tggaatgtaa ttaagtgagg gtattaatat gaagatattt
    14041 tctaataaag atataaaaat atttttttta atgcttatat ctattttagt aatgtttatt
    14101 atagtagggc aaatagtggt tataagtata actaacaatt ataaaaaaac gttgatagag
    14161 catgattata atatagctgg atacttatat agtataggtg ttgataaatc taaaatacca
    14221 tcagcatttg ttgcacatga agataaatat attttaaaag gaaaagaaat actagataca
    14281 gctggatatg gatttgatat agatgttagc tttacaccaa gtgtaaaatt gtttcaaagt
    14341 aaatatataa aaactatgtc tatctattta ttagtatttt ttactatgat tatttttata
    14401 ctatatatgt atttttttag gcaacaaagt aagatagaag aggctagtta taaaattgat
    14461 ttatttatga atggaaatat aaatgaaaga ctaaatacat atgaagaagg tagcttatca
    14521 aaattattta gttcaataga tgttatgtcg acatctttaa atacacatat attaaaagaa
    14581 aaacagagca gagaatttct taaaaataca atttcggata tatcgcatca attaaaaact
    14641 ccacttacag ctttaataat gtacaatcag atactacaag aagaaagtca taatagtgat
    14701 gtcgttgaag cttttgtaca aaaaagtcaa agtgaactag aacgcattga aacattgatt
    14761 aagaatttat taaagattac aaagatagat tcaaaaacaa taattctcaa taaaaataac
    14821 gttaatctta aaaatttaat tgtcaaaatt ttgtatagct ttgaaactag ggcagaaaaa
    14881 gaaggaaagg ttatttctgt aaatggttca gaaaatacat tgttgttctg cgattatgaa
    14941 tggatgtcag aggctttaag taatcttata aagaatgcat tagataatac aaaagagaat
    15001 gataaaataa cgatagagtg gtttgagacg actataacca ccattgtttc agttaaagat
    15061 actggaaatg gaatccatgt tgaggatatt catcatatat ttaaaaggtt ttatagaagt
    15121 aagttttcaa aagataatca aggtttagga ctgggattac cactagttaa atctattgtg
    15181 gaacaacata atggtactat ttctgtagaa agtaaactat cacaaggaag tatattcacc
    15241 ataagttttt taaagcttac taatatgtaa gataaaatac atcttgcagt aaggtatata
    15301 gattattatt atattaatca attagaaagg tgagagagaa aatggatatt cttgtggtta
    15361 ataatttatg taaaacatat ggaaatggat atacaaaggt agaggcattg aaagatgtat
    15421 cctttacagt ttcaaaagga gagtttgtga ctgtagttgg agaatctggt tcaggaaaga
    15481 gtacactatt aaatctctta ggaggtcttg atactccaac atcagggaga atatttattg
    15541 atggtaaaga aatatgttca atgaaagagg aaaaacagac tatttttaga cgtcgtaaca
    15601 tagggtttat atttcaggca tataacctta taccagaact aactgtggag caaaatataa
    15661 tattcccatt gttattagat tataaaaaac cagatactat ttacttagat gaagtattga
    15721 ctattttagg tcttaaagat aggaaaaatc atcttccaaa tcaattatct ggtggtcaac
    15781 aacagagagt tgcaattgga agggctttga ttacaaagcc aagtattata ctggcagatg
    15841 agccaacggg aaatcttgac agtaaaaata gtaatgatgt aatttcactt ttaaaagtga
    15901 ctgcagaaaa gtataatcaa accattatta tgataactca taatacgaat atagcttcta
    15961 cagcagatag aatactacag gtttctgatg gtgtgcttac agacctgggg gtgaatagag
    16021 aatgagaagc tacttagaat tagtaccaca atatgcaaaa gtacataaga aaaaaaatag
    16081 aactacaatt ttatgtatta ttattgcagt atgcttagtt actgctatct ttggacttgc
    16141 agatatggct atacaatgtc aaaagataca atttattaaa gatgatggaa attggcacat
    16201 agtaattaga aatattgatg aaaagtttat atcagaaata aatagtagag tagatatagc
    16261 tcaccatggt agggggcaag tcgttgacaa tggagagttt aaatcaaagg agattttgat
    16321 acaaggttta gatgaagaag tagcaaagca atttaactta gaaataataa ggggtcgtta
    16381 tcctattggg gagaatgaga ctttaataga tgaggatgca gttaaaagct ttaatctaaa
    16441 aataggagat tttatcaaaa taaaattagc agatggtaga aataaaaatt ataagatagt
    16501 aggtgaatat tcatcaatat caagcttaag agctacagat aaacatggat taatactttc
    16561 aatattgggt acacaagcta ttaaaaaatc agaaacgtac gattattatt atattacatt
    16621 taaagaaaag gttaatatta gaaaagccac ttctgatatt aaaaatacct tcaatttaag
    16681 tgataaacaa attggtaaaa atgaaagatt actttctatt ataggtcaag gtgactctga
    16741 cttttctaaa ccattgtatt taacagcagg attacttttt gtacttgttt tagtagcaag
    16801 tattatcatg atatataata gttttaacat gagtgtaatt gagagagtta aattttttgg
    16861 tctgttacgt tgtctagggt catcaaaaca tcaagttaaa aaatttgttg ttttagaaag
    16921 tttaatttta agtataaaag ctattccaat aggcttagta ttaggaagtc ttgtaactat
    16981 tatatcttct atatttctta agtatgttaa tgagttattc agctcaatgc caattttaaa
    17041 agttagtttt attggtattg catttggaat aattgtaggg tttttaactg taatattatc
    17101 agctattatt ccagcaaaaa aagcttcccg tgtatctcca cttagcgctg tacgtgggaa
    17161 tctaatgtcc aaagaaattt taaataacgg gaagacaagt aaagttgcaa atataggaag
    17221 ttttaaaatt gagacttcta tgggattaaa tcatgctttt tcaagaaaga aatcttttgt
    17281 acttatgact tcttcatttg ccattagtat tatactattt ttaggtttta gtgtgcttat
    17341 agaccttatg tatcaaggac ttaagcctat gaagccagaa gctcctcata tatctattgt
    17401 tgaccctaat tttaagtctg ttttaactaa ggaagatatt aatgaaataa gcaatatcaa
    17461 aggagtaaag aaagtataca gtagaatgat gacggatata gaagctacat ataatgggaa
    17521 gaagacaaaa tcacaattaa tttcttatga aaagtatcaa tttaattggg caaaaaaata
    17581 tctattaaaa ggagaagtta atgaaaataa actacagtca gaaaaccttg cattagtaga
    17641 agaggggcat ggatttgata taggagataa gatatatatt aaaaatggaa atgctgaaaa
    17701 agagttagag gtaggaggta tactttcctc aattccattt gaggctaaag ataaatatat
    17761 tggaaatatt ataacatctg aaaatacttt tacgaatata acaggtataa agggttatat
    17821 aataatggat attcaggttg ataaagatac tcctggagat ttaattgaaa atataagacg
    17881 tgtagtagat gataacttag aggtcagaga taaaagacaa agtaacttag aggttaaaaa
    17941 ttcgttttat actatggcaa catttgtata tggatttgtg tttattattg cgattataag
    18001 catgtttaat atcataaata gcatgaatat aagtgttaca agtagaaaga attactatgg
    18061 tgttatgcgt gcagttggca tatccaacag acaattaaga agaatggtaa tagtagaggc
    18121 aggttcatat gcagtgagtg gttgtttatt aggtagtata ctaggattaa tattacatag
    18181 gtatatgttt atatcgttag taagctcaat gtttcattta gagtggcaag taccttttaa
    18241 tttactactt atcactgtac taactatgat aataataact ttattatcag taagaaaacc
    18301 aatcaaaaag atttgtgaat tagatataat agactcaata aatgcacaat aaatataggt
    18361 attgatttaa attaaaaaaa cgaagtaaaa atgaaataga aaatattttt catttttact
    18421 tcgtttttta tattataaaa tttttgttat gttacaaaat ttctataaag atgatgtgaa
    18481 tctaaacatt atatgacaac gtgagcattt aagttaaaat attttaaata tactatttta
    18541 gataagttcc ctcttcatct tgataaatta atcctttttt cataagcact ccaagagctc
    18601 gtttaaaatt tttcttactt gaattaaata atatagaaat atctttaggg tcagatttat
    18661 cattaaatct catatatcca tcagaacctt ctaaataact taaaatctta ttttctaaag
    18721 tatcaagttc atcctttcta tttcctctag gagaaagacc aagttttcca tcttcatata
    18781 tttttatgac atgtaaattt tcaagaacat caccagtttt tagttcagta aagtactcat
    18841 tatgaagtat tacaccagca tatttattgt ctacacatat cattgcagaa ttattagttt
    18901 ggaatccata tacaactcca gttacaatat ctcctacatt gtaagtatgg tctgttaata
    18961 agtatgaatc tatatctgta gtagcagcaa ttcttttgct tttgtctaaa tatatataaa
    19021 ataaatattt ttcgtctcta aatagtggat aagtcttagc tttaaaagga actaatatgt
    19081 ctttaggaag tcccatatct ataaaagtac caatgtctgt attatcaact acttttaaat
    19141 gtgctacatc cccaacctta gctaaaggcg gtattaaagt tgcagcagtt ctgtcatcag
    19201 aatctttaaa tatgaaagca tttacttcat cacctatgtt tatttcattt tttccgatta
    19261 atctattatg aagaagtata tcgtcttttg tgttattagt ttgtccatcc aaaaaatatc
    19321 caaattcagt ttttcttttt actgtaagtt tattaaaatc acctatgttt atcaaattaa
    19381 aatcatcctc tcattttata tttataattt agccataata tacttatgta gtagtttgtc
    19441 acagtatcta tattagtatt agtgaaattt acaataaata atatagttat ttatgtattt
    19501 ttcaattctc tagcttctta tatagtataa actccaattt cttttttgtc tttaggtttt
    19561 attaaaattt ttacaaaata agttaaaaag tattgaaata aaatttcttt taaagtataa
    19621 ttggtatata ccaaaattgg tatataccat atcgaaaagt ggtgactata tgaaaatagt
    19681 aaataaatct agtaatatac cattgcatac tcaattaagt tcaataataa gagagatgat
    19741 agaaactggt gagcttaaag agggcgatgc aataatgcca gaaagagaac tttgcaacat
    19801 acaaaatgta agtcgtatga cagtaaataa aaccattgtt ggattagtta cagaaggact
    19861 tctttatagg gtacaaggta aagggacatt cgttgcaaag caaaaaaaga agtatcagtt
    19921 ttcaaatgta aaaggtttta ctgatgttat gaaagaaaag ggagtaaaca taaaaacgga
    19981 tatattatcc tttgagatgg aactaccaga tgatttagtt aaaagaaagc ttggaataag
    20041 tgataatact acaaatatat ataagattgt cagacttaga tatactgatg gagagccatt
    20101 tggattagaa atagtatatc tatcagaaga aatgtgtaag ggtctaacaa aagggatatt
    20161 ggataattct tcattatata gggttttaaa tgaaaaatat ggctataaga tacaaaaagc
    20221 tgaacaggta atggagccag taatactttc agatgaagaa agtaagcttc ttgaaacaga
    20281 tgaaggtgct ttagctctta aacttcatag aaattcctat aatagagaag gtagacctat
    20341 agaatatacc atatcaatat ttagaacaga taaatatcaa tatgaaatag tattgagtga
    20401 gtaggtgaat aatatgaaat gtttaattaa tggaaagata atattaaaaa atcaaatctt
    20461 agaaaataaa gtattagtat ttgatgaaaa aataattgat atagctgata gtgtaccaaa
    20521 agattgtgaa gttatagatg ctgatggaaa atatatatct ccagggctta ttgatattca
    20581 tatacatgga aacatgggaa aagatacaat ggattcgact gatgaatcta ttgaaacaat
    20641 ttcaaaatca attatgagac atggagtaac atcttttctt ccaactacaa tgactatgga
    20701 taaagaacat gtttatgatg cacttgaagt tattaaaaaa gcccaaaata gaaagcttga
    20761 aggggcacaa gtattaggag cacatttaga aggacctttt ataaatgaga attataaggg
    20821 agcacaaaat gaaaaattta taataaattc aaaatacgaa tttataaaag aatataaaga
    20881 tgttataaaa gttataactt atgctccaga aaaagatatt gattttgatt ttactagaga
    20941 aataaaaaga tgtacagata tagttttatc tattggtcat agtaatgcaa attatgacca
    21001 agctaaagaa gctataaatt taggagtaac taatgtaact cacatgttca atgcaatgac
    21061 tggtttaaac catagagacc caggcgttgt tggtgcagca cttacaacta atgtgtacag
    21121 tgagttaata gcagatacaa tccatataaa taaagattta tttcaattta tactaaataa
    21181 taaaggaaaa gaaagactga ttttaataac agattctata gaagctggtg gtcttgaaga
    21241 tggcaattat tctcttggag gtcagaaagt catagttaag ggtaatgaag ctagacttga
    21301 aaatggagca ttagctggaa gtgtgttgtc tttaaataaa atggtattta acttcttaaa
    21361 taatacaaac cttaaagtga atgaagcaat taatttagct tctttaaatc cagcaacatc
    21421 tttgggaata aatgacaaaa aaggaagctt agaaataggt aaggatgcag atatagctgt
    21481 atttgatgag aatttagatt gtaaaatgac actttgcttg ggggaagtag tatataaaaa
    21541 tatatagtat acaaaacaaa ccttaaagac agtaaaaaca atataaaaaa taataaatta
    21601 aacttacatt agtaaaagta gtagttaaaa tttaggagga ataagatgag agtattagtg
    21661 tgtaaagatt atgatggaat gagtaaaaaa gccgctgaaa tgatagcagc tcaaatagtt
    21721 ttaaaaccaa attcaatact gggactagct acaggaagta caccagtagg tatgtataga
    21781 gatttagtaa aaaaatacaa tgataatata gtagattttt cagatgtgat gagctttaat
    21841 ttagatgaat attataagtt accaatatct aatgaccaaa gctatgatta ttttatgaaa
    21901 gagaatctat ttaatcatgt aaacataaag ccagaaaata ctcatctacc aaatggaatg
    21961 gctgatgata ttgaaaaaga gtgtatgaac tatgaagctt ctatagatgc agctggtggt
    22021 atagatgtac aagtacttgg aataggtcgt aatgctcata taggttttaa tgaacctgat
    22081 actaaatttg caaaaagaac tcatgtagtt gaacttacag aatctacaat agaagctaat
    22141 gcaagattct ttaaatcaag agaagatgtt cctaaaaaag ctgtaagtat gggaataggt
    22201 tcaatattga agtctaagaa aatattgctt ttagcttcag gagaagaaaa agctgatgca
    22261 gtatataata ctgtttacgg agatataact ccagaagttc ctggttctat acttcaactt
    22321 cataaagaca ctatagttat agtagatgaa gcagcagcaa gtaaattgaa tccaaaagat
    22381 tataaattag tataagaata gaatgtagtt taaataaaaa atagctatca ttgaataatc
    22441 aaatttattt aatgatagct atttttattt aaattagtta ttattgttta aattacttgc
    22501 ttattacttt ttacgaaaac tcgttatcaa gaagtatcca aataagatgt taaaaattat
    22561 tatgtttagt gggattctat caagcataat aaaattacct ataattggga tattaccaac
    22621 tggaaacata aagaagaata caggcatcag tgatagtaaa aaagatggaa aacaaagaag
    22681 aagtaatctt ggaatatcaa tataccaact accatccttt ttgtattctc taatcaataa
    22741 ttcagttcct agtaataaac caataccacc agaggaaatt aaattaataa aaatgtatct
    22801 tttaaagtct tgcatataac cagtgtaaaa ttgagtatag aaatcataat ttaatttaac
    22861 ggctaaaaaa tacataagca atagaatgat taaaaataaa agatatctaa gagctttttt
    22921 cattttaaat tctcccttca gaaatacttt atttagtttt attttgttgg aatctgattt
    22981 tatcatttag tttaagaaat ccataatatt agtgaagaat gaaataagta ttatatatga
    23041 ataaatattt ttagaattaa ggtgaattgt agtgcttaat ataactataa tattaattgt
    23101 ttgaatattc aataaaaagt tcgaaaaata tcaattctga tataaactga ataaatacag
    23161 ttgaatatta aattattatt ttatcaaaaa tatgcaaagt actacacctt caaatatcac
    23221 ctaaagtaat taaaaggcaa ttaaagtgaa gtagttcaag tatttctaaa ataagtttaa
    23281 taaattctat aataatttat tttttgcctt aaaattgcct taaaatccaa acaattttaa
    23341 aactaatgta ctataaaaag ctggtataat ttaaatatag taaaaaataa gatttatctt
    23401 atctattggg atttaattat ttaatcaata tatttatacc atttaattta aataaaaagt
    23461 ctattaagga gtgagcttat gagtaagtta atttatatag cagatgatga agataatata
    23521 agaaatttgg taaagacatt cttaaaaaat gaaggtcatg atgttatgga ttttaaaacg
    23581 ggtgatgaac ttttagaaca atttaatata aaggagtgtg acttagtaat actagatata
    23641 atgatgcctg gctcaagtgg ttttgaagta tgtacaaaac ttcgtgagaa aagtacagtc
    23701 ccaataatca tgcttactgc aagagataca gatatagatt atattacagg gataacctta
    23761 ggtagtgatg attattttac aaaaccattt agcccaatgt ctttggttat gagagtaaaa
    23821 tctatattta gaaggataga gtttgaaaag aaacaaaatt atgataaata tagtaactcg
    23881 atagatatgg aattaaaatt tggtgatgta ataataaata aaaagaataa aatcgttaca
    23941 agtaaaaatg taaatataga ccttacacca aatgaatata acctattgac ttatttgttt
    24001 gaaaatatag atagagcaat ttccagagat gaattattaa acaaaatatg gggatacgat
    24061 atagaagttg agacaagggc tgctgatgat acagtgaaga gattacgtaa aaaaatttta
    24121 gatacaaata ttttaataga aactgtatgg gggtttggat ttaggttgaa ggagaaaagt
    24181 taagatgaag aatggaaatg acaagaatag aattggaaag attaaatcca aatttaaatt
    24241 aaagttctca aagaaaaata taagcataaa aactaggatt ttgttgagta tactttgttt
    24301 gataattata gtatttatga taatattagt atcttttaat gtatttcttg atacatatat
    24361 aaaaacaact gcgaatgaag aattgacaaa gtctacagaa atagtagaac atatggatag
    24421 taattttaga cctattaagc caccacaaga tgatggaaag cttcctccca aagtattatc
    24481 taattttatg agaaatgtac aagataaagt taggatggca gaaacacaat cagatgctga
    24541 tgctatggta gttgattcta agtataacct gatatttcca acaagagagg acgatttctt
    24601 aaaaaatgtt gatgagatgg agctgattag ggagtgtatt caaaatgaaa aattagattt
    24661 aaattcagat gcaaatacac ggatatctac cagaaataag gattattata tttcaactgt
    24721 aaaaattacc agtatatatg gtgaacaaga caagtatctt atacttttta tagacatatc
    24781 aaaaactcta aatctagcac aaaagataaa tattgtatta atatctgtaa tgtgttttgc
    24841 tggaatatta gcaatattta cagctgtgat tttatctgag aaaattgcta aaccgataaa
    24901 agagttgtgt gagtttgcaa aaaaaatggg tcaaggagat ttcaaaagaa cctactttga
    24961 cttttcagat aaagaattag tagagctctc aactgttatg aataagagtg ctgagtatct
    25021 ggataagtat gataatgaac aaaaaatatt ttttcaaaat gcatctcatg aattaaggac
    25081 accacttatg tctattaaag gttatgcaga agctataaaa tataatgtta tagatagtaa
    25141 acatgcaagt gatataattc ttgaagaaag tgataggtta agtgatatgg ttgaagattt
    25201 attatacatt tctaaaatag ataatataac taaagatttt gaacttgtag aatgtgattt
    25261 aagagaagta ctttcaaact gtggagctag gcaaaatgta agagctataa ataaggggat
    25321 aaagtttatt tatgaatttg atgaagaaat ggttttattt gaatgtgatg aaaaaaacat
    25381 ttccaaagca tttatgaatc ttatagaaaa tgctttgaga tacgctaaga gtgaaataaa
    25441 aatagtgtgt aagtataatc aaaaaaatat agttgtgata atagaagatg atggaattgg
    25501 aatcaagaaa gaagatttac ctcatgtttt tgaaagattc tataagggag taggaggaaa
    25561 tcatggaatt ggattatcaa tagttaaatc tattgtaaat aagcatggtg ggcgtatata
    25621 cgtagaaaat ggcaaaaaag gagctaaatt tactatatta tttaaattgt aaaaaaatta
    25681 gagaaaatat agagatgttt gaagttgttt tttatatata tctgttgtat actgttgaaa
    25741 aaagaacaat attaagctga catatattac gatagttgac atttaaagta aatgcttaaa
    25801 tatagatacg aaaggaaaag taaaatctga agtgtattta ggtttaagta agcttcttat
    25861 tttataaaaa atatgtatga aagaacagct gatttttaat attacaaatt tagtaacggt
    25921 tgtatttgaa gcttttgtca tccatatgtt tttatcagac tttttaggcc agaaagaagg
    25981 gtatataaaa gttgtaagat atgctaaact gggttttata atatgtttag gattctgtaa
    26041 tttaataact ttaaacccta aaatcacaat gcctttaatt ttcatcctta ttttttcaac
    26101 atcattttta tataaaggaa atttaaagac acgattgttt actactgttt tattaagtat
    26161 attctttata ctgtcagaaa ttgtagttac aagtattttt gttttatttg taaaagaagg
    26221 ctttgaaata atgcttgaaa ataatagtat aagagtattg gcgacaattt tatctaaaat
    26281 tgtctttttg ttgacttgta aaattatttg tctatttaaa aaagatgtac atttagatat
    26341 gcccataaag tattggctcc ctttattttt aatacctata tttagtttat ttctgtctgt
    26401 ttctatcttt gatgtaagta aattttttag tcttgaaagt ttaaaatttc taagcttaat
    26461 atctagtgtt ggtattttat atattaattt tattgtcttt tatttattta aatttattat
    26521 agataaaact aaactatcta tgaaatatga actacttgaa aaagaaataa ttcataagga
    26581 agaattaaga cttagtaatg agtgttataa aattattgtt gaacagactg attctgtcgt
    26641 tttcgaatgg aatatcaaag aaaataaatc atttgtatcg caggcttgga ctgaaaaatt
    26701 tggatataac aatgcatgta agaatatttt taaagaaatt aaagataaag acttagttca
    26761 ttctgaagat aaagctatat ttgaaggttt tcttgaaagt attaaaaaaa agaatatgca
    26821 caatcaagca gtatatcgtt taaaaaaatc taatggtgaa tatatttggt gtagaacatc
    26881 aattacaagc atttataatg atgaaaatga acttttaaga gttgtcggag taattgtaga
    26941 tgtagatagt gatataaaaa aatatgaaga gttaagaact agagcagaaa gtgactcatt
    27001 gaccaatata tacaataaag gtacatttga aaaattagtg gaagaaacta tagttatgaa
    27061 tacaggtgat aaaaaagatg cattattcat tattgatttg gatgatttta aagaaataaa
    27121 tgataatttt ggtcatccat ttggtgattt tgtactaaaa acatttgctg ataagataca
    27181 aactagtttt ggtagtaaag acttagtcgg aagaattggt ggagatgaat ttgttgtata
    27241 tatgcaagat tatgttacag aagtaaattt gcataaaaaa gctaaagaat taaatagagt
    27301 actttcggat aattacactg atttgagttt tagttttgat gcttctgtca gtataggtat
    27361 tgcaaggtat cctcaagatg gaacttcatt ttttgaattg tttaaaaatg cagatagagc
    27421 actttatagc ataaaagcat caggtaaaaa ttcatattgt ttatttgaag aagaactata
    27481 tgtacagtga atttgaattt agattttatg tgagagtaag atttatatat acttgtggct
    27541 gtctgattta taaaatatgt tactttgtat atttttatat gtttcagtaa ggttaattaa
    27601 cataagcaaa ggtgtaagta aatttatatt agtttaagtt tacttacacc tttataaaaa
    27661 tacaaataat agattcattt acattcttaa atgattaaag ctctttacct tctaaacatg
    27721 cataacatat cgttataatt ccagtaaata agactaaaat acccattcct aagattacag
    27781 tttcattatc tattactcca aatgttttta aagtaactta tttcgctttg tatcataata
    27841 atttgtctct ttttacattt taacttctgc tgagatttga gttagatatt cgttagaatc
    27901 tcgcacactt atatcatata gaagatattc ttcataaaca aaatccccaa tacgtaaatt
    27961 attctgatta aaaaaattta ataacttttc ataagccttg taaatagttt cataactccc
    28021 tttatgataa gcagttacat aaagtccctt tggtttgatt gatacaggat atttcttgta
    28081 ctctttatta acttttgtaa ataaatatga atatgattca aagtctttat taattatatc
    28141 ttcaccttta atgattgagc caatcgtacc ataatcactc aattcatagt tgtccataaa
    28201 gttaatacat tcatataaaa aattttcttc ctcatctcct aaaaactgtt ctttatatgt
    28261 aacaggtgtt ttgaccaagt actcttcttc atgttctttt aaagtaatag tattcgcatc
    28321 tatattacag gcatttttag tgaatgaaat agtagattcc attagagctt gaatattatt
    28381 tagtttttca atttcatttt taatatcaat ggttttcttt tctaaaagct caattagtaa
    28441 attaggtgtt cttttgtcta tataagcttt aatttctttt aaaggcattt ttacttccct
    28501 aagtgaagaa attataccaa aaatgctaag ttgatggtat gagtagtatc tatatccatt
    28561 ttctttcttt aattctggtg agaaaagacc tatatcatca taatggaaaa gtgttttttt
    28621 attgattcca caaatctttg caaattctcc agttgtaaaa taattttttg aaacttgact
    28681 cataattata attcctcctt gactatcctg ttacagtata gtttatcata gtattttgta
    28741 aaggagtgtg attatatgaa aaaattaatt cattttttaa aaccatatag agttttaatt
    28801 gttgtagttt tgatatttac gtttttacaa acacttggaa ctttgtatat accaacactt
    28861 acagcaaata tagtaaacaa tggtgtagta aagggagata tagattatat tgtaaaaaca
    28921 ggtttaatga tgatgatagt agctggtata acagctttat cagctgtgtt agtttgtaaa
    28981 gtatcagcaa atctttcatc tggattttgt agagatatta gagaagcagt atttataaaa
    29041 tcacaagatt tatcaataaa tgattttaat aatataggta cagcatcaat gattactagg
    29101 agtactagtg atattacttt aataggtcag tctgtgttta tgtttattca attagtatta
    29161 ccagcaccaa ttataactgt ttctggtcta ttcttagcat attctataga taaagcaatg
    29221 acaattatta ttgttgtagt aatgttttta ttcatgcttt cagcattttt agttggtaaa
    29281 aagcttataa agttgtttaa aatgatgcaa ataaaaatgg acaatatgaa tagggtgtta
    29341 cgtgaggtag taactggagt aagagttata agagctttta ataggagtca ttttgaaaaa
    29401 aagagatttg atagaactgc aatagattat tctgaaacag caatttcaat aaataaaata
    29461 tttgcagtac ttatgcctat tgtaatgtta ataatgaatt taggtatagt aagtattatt
    29521 tggtttggtg ggatgagagt cagtaatgga aatatggaaa taggtcatat aatggcactt
    29581 gttgaatatt gtatcttaat tttattctat ttaatcatgg gagtaatggt atttatgtac
    29641 atacctagag caggtgcatg tgcagataga gtaaatcaga tattagatat agaacctgaa
    29701 attgtagatg gaaatggtca taaagatact gtctcagaga gaggacattt agtatttaaa
    29761 aatgtaacct tttcatatgc acaatcagaa gaacctgtgt taaataatat aacatttgaa
    29821 gcaaaatctg gagaagtaac tgcaattata ggaagcactg gctcaggcaa atctactatt
    29881 gcaaatataa taccacgttt ttttgaaatt caatctggag aaatatctat aaatggtcag
    29941 gatattaaga agattcctca aaaagaactt agagataaga ttggatttgt accacaaaaa
    30001 gcttttttat ttagtggaac aatagaagaa aatataaggt atggaaaaga agatgcaagt
    30061 attgaagaag taaagcatgc tgcaagtata gctcaagctg atgaatttat ttctgatatg
    30121 gaagacaagt atgactcatt tgtagcacaa ggtggaaata atttgtcagg tggtcaaaaa
    30181 cagagaatat ccattgcaag agcgttagtt agaaagcctg aagtatatgt ctttgatgat
    30241 agtttttctg cattagattt taaaacagat aaaagactta gaaaagcgtt gaaaaatgaa
    30301 atcaaagatt catcagctat aattatagca caacgtataa gtacaatcat ggatgctaat
    30361 cagattatag ttttaaatga tggaaaaatt gtaggtattg gaaaacataa agatttactt
    30421 gaaaattgtg aagtttataa gcaaattgcg gattcacaac ttagtaaaga agaacttgca
    30481 taaaatgaag aattaatctg atatttggag gtgtatgata tgagtgaaaa aagaatagat
    30541 gaacaagata tagaagtact tagttttgaa gatggcatgt cagcagaaaa agctaaggat
    30601 gcaaaaaaaa ctactaagag attattaaaa tatatggcaa aacaaaagtt taaaatatta
    30661 attattttta tttcagtatt gataagttca gcgcttacag ttttagcacc tatggttatg
    30721 ggaaaagcta ttgaccaact atttaatgga ataaaaactg cagtccaaac aggtacaaaa
    30781 ttcagtgtga attttagtac tatggggggg atagtatcaa tacttctagg gttgtactta
    30841 attagtgcag tatttatata tattcaacag tatattatgt caggagttgc acaaaatcta
    30901 gttcttagca tgagaaaaga tttaagtgat aaactcaata aacttcctct taagtactat
    30961 gattctcata aaaaggggga aacacttagt atagtaacaa atgatttaga aaaagtagca
    31021 gatagtttac aagaaggatt aatgcaactt attacagcag tagttacagt agttggttct
    31081 attgtaatga tgataagtat aagtgtacca cttacaatag tatcagctat aacattactt
    31141 gtttcattgg gtattactgt tgtaattgca agaaaatcac aagaaagatt ctctgaaaat
    31201 caaaaggcac taggagagtt aaatagcaat atagaagaga tatttactgg tcaaatagtg
    31261 gttaaagcat ttagtaaaga aaaggatact ataagaaact ttaaaatatt aaatcaaaat
    31321 ctttataatg caagtagaaa agcacagttt tcgtcatatg caatatctcc aattattaga
    31381 tttataaacc taattggcta tgttattata gcagttgtag gtgggatatt tgcatcaact
    31441 ggagcaatga ctcttggtag tatacaagcg tttattcaat atgtaaatca agcatcagag
    31501 cctactacag aaatatctta tattgtaaat atgcttcaag cagcaatagc atctgcagag
    31561 agagttttta cagttatgga cgaggtggaa gagataaagg atgaagaatc ttcaaaggtt
    31621 attagcatgc ctaaaggtaa agtacaattt gagcatgtta aatttggata tagtgatgat
    31681 tttattctta tgaaagatat taatatcaat ctaaatgcag gagataagat tgcaattgtt
    31741 ggacctacag gagctggaaa gacaactctt gtaaatttac ttatgagatt ttatgagata
    31801 caaggtggaa gaattactat tgatggtgtt aatataaaag atttaaagcg tggagaactt
    31861 agaactatgt ttggtatggt tcttcaagat acatggctgt ttaatggaag tataaaagaa
    31921 aatattgcat atagtaagtc agatgccaca atggatgaaa ttgtaagagc agcaaaatca
    31981 gcaagagtag accattttat aaggacttta ccacaagggt atgacactat attgactgag
    32041 gatgcttcta atctatctca aggtcaaaag caacttctaa caattgccag ggcaatactt
    32101 tcagacccat cagtattgat tcttgatgaa gcaacatcta gtgtagatac tagaacagag
    32161 gtagaaattc aaaaggcaat gaataacttg atgaagggaa gaactagttt tgttattgca
    32221 catagattat caactattcg agatgctgat ttaatattag taatgaaaga aggaactatt
    32281 attgaacaag gaagccataa ggaacttatt gaaaagaaag gattctatga agaactttat
    32341 aacagtcaat ttacaagtga atatgatgaa gatgttgtat gattatcaag ttttaggcaa
    32401 ctaaatgatt gataaatatt aagttaaata tagtaacatg taaggttata tggaataaga
    32461 gtatttctct atttcatata acctttttta tttatcaaaa taagataaaa tttcctttct
    32521 aaattagatt gaagaatgta tttatcaata taaaagtaaa ataatcatta ttattagtga
    32581 agtaaatatt gtttgccaca tatatgccat aaagatgcac ttattttacg gagatttaac
    32641 aaagtagtgt aaagtatact ctaaatataa aataaatcaa atagagttaa ataaattgag
    32701 aggtgatata aatagtgaat aaaaaattga actatagatt tgaaatgaag cacaaaataa
    32761 ctgaagcaga tgtgttagct ttaaaatcaa gactctatca aataatgaag aaagatgaaa
    32821 atgcatctaa agatggaaaa tatcttatta ggagtttata ttttgatact cctgaagata
    32881 aagcactttt ggataaatta aatggcgttg caataagaga aaagtttagg ataagatttt
    32941 ataataatga ctgctcttat ataaggctag agaaaaaaat caaacattac aacatgacat
    33001 caaagctatc aactaattta accaaaaaag aagtaataaa tatactaaat aatgatattg
    33061 aatttctaaa agagtcgaca aattgtttat taagagaatt ttatttgaaa ttaaaatgtg
    33121 aaagattaga ggcaaaaagc atagttgatt acaatagaga agcttttatt tatccagttg
    33181 gaaatgtaag agttacaatc gatagtgata ttaaaacttc tgtaaattcg gtagatttat
    33241 ttaataaaga tttgccaact gtttcggtaa ttgatgagaa tatgactgta ttggaggtta
    33301 aatatgatga atttatacca gattttataa aggatttaat tcaaattaat aagactacct
    33361 ctacagcagt ttcaaagtat gcttcaagta gattatatat ttaagaataa aggctatgat
    33421 ttatataaag atatacataa ataaggttaa aaaacaaata agttaaaaat aaataaaata
    33481 aaaaataaat aagttaaaaa taggaaggat gattttaatt atgacattta atgatatttt
    33541 taaatcaagt tttatagaaa acgtatcagg tttttcattt gtggacagtg ctttagcact
    33601 aggttcagct tttttagtag gtttgtttat atatatggtc tataaaaaga cttatatggg
    33661 aattatgtat tctcgaccat tcaatgtgtc gcttgtagca cttacaatgc ttacaacttt
    33721 tgtaatattg gcagttactt caaatgtagt tttatcctta ggtatggttg gtgctttatc
    33781 tatagtaaga tttagaacag caattaaaga cccaatggat ttagtatttc tattttggtc
    33841 attgggttca ggtatagttt taggagcagg tttgattccc ttagctgtca tgggttcaat
    33901 aattatggga ttgattctaa tattcttttc aaataaaaca atatctgaaa ctccatatat
    33961 attgatggta aattgtaata atgaagattc agaagatata gcaactgata aaattaaaaa
    34021 agtatttact aaatatcaaa taaaatcaaa aagtgttaca ccagaaaaag gaatagaatt
    34081 agtgtttgaa gtaagaatga aagatggaga aacaagtctt ataaatgact tgagtcaagt
    34141 agatggagtt actaatgcag ttcttgtaag ttataatggt gactatgtag catagagagg
    34201 agtaatcttt tatgaaagat aaaaaattta cccttcttat ctcgattatg attatatttt
    34261 tatgtgctgt agttggagtt tatagtacat ctagcaacaa aagtgttgat ttatatagtg
    34321 atgtatatat tgaaaaatat tttaacagag acaaggttat ggaagttaat atagagatag
    34381 atgaaagtga cttgaaggat atgaatgaaa atgctataaa agaagaattt aaggttgcaa
    34441 aagtaactgt agatggagat acatatggaa acgtaggtat aagaactaaa ggaaattcaa
    34501 gtcttatatc tgtagcaaat agtgatagtg atagatacag ctataagatt aattttgata
    34561 agtataatac tagtcaaagt atggaagggc ttactcaatt aaatcttaat aactgttact
    34621 ctgacccatc ttatatgaga gagtttttaa catatagtat ttgcgaggaa atgggattag
    34681 cgactccaga atttgcatat gctaaagtct ctataaatgg cgaatatcat ggtttgtatt
    34741 tggcagtaga aggattaaaa gagtcttatc ttgaaaataa ttttggtaat gtaactggag
    34801 acttatataa gtcagatgaa ggaagctcgt tgcaatataa aggagatgac ccagaaagtt
    34861 actcaaactt aatcgttgaa agtgataaaa agacagctga ttggtctaaa atcacaaaac
    34921 tattaaaatc tttggataca ggtgaagata ttgaaaaata tcttgatgta gattctgtcc
    34981 ttaaaaatat agcaataaat acagctttat taaaccttga tagctatcaa gggagttttg
    35041 cccataacta ttatttatat gagcaagatg gagtattttc tatgttacca tgggatttta
    35101 atatgtcatt tggtggattt agtggttttg gtggaggtag tcaatctata gcaattgatg
    35161 aacctacgac aggtaattta gaagacagac ctctcatatc ctcgttatta aaaaatgaga
    35221 catacaaaac aaaataccat aaatatctgg aagagatagt aacaaaatac ctagattcag
    35281 actatttaga gaatatgaca acaaaattgc atgacatgat agcatcatat gtaaaagaag
    35341 acccaacagc attttatact tatgaagaat ttgaaaaaaa tataacatct tcaattgaag
    35401 attctagtga taataaggga tttggtaata aagggtttga caacaataac tctaataaca
    35461 gtgattctaa taataattct aatagtgaaa ataagcgctc tggaaatcaa agtgatgaaa
    35521 aagaagttaa tgctgaatta acatcaagcg tagtcaaagc taatacagat aatgaaacta
    35581 aaaataaaac tacaaatgat agtgaaagta agaataatac agataaagat aaaagtggaa
    35641 atgataataa tcaaaagcta gaaggtccta tgggtaaagg aggtaagtca ataccagggg
    35701 ttttggaagt tgcagaagat atgagtaaaa ctataaaatc tcaattaagt ggagaaactt
    35761 cttcgacaaa gcaaaactct ggtgatgaaa gttcaagtgg aattaaaggt agtgaaaagt
    35821 ttgatgagga tatgagtggt atgccagaac cacctgaggg aatggatggt aaaatgccac
    35881 caggaatggg taatatggat aagggagata tgaatggtaa aaatggcaat atgaatatgg
    35941 atagaaatca agataatcca atagaagttg gaggttttgg taatagagga ggaggctctg
    36001 tgagtaaaac aacaacatac ttcaaattaa ttttaggtgg agcttcaatg ataataatgt
    36061 cgattatgtt agtaggtgta tcaagggtaa agagaagaag atttataaag tcaaaataag
    36121 attaaaattg aatataaata attttaatac tgttaagtct aaatatttac ttagcagtat
    36181 tttttagaaa ataatgtgtt tgattaataa tataaggtaa taaattgata aaaattaaat
    36241 acagcatatt aataatacat aataaagtaa taaaaaactg tttaagtata ataacttata
    36301 tttagacagt ttttttcatt tataaataat ataaatgaaa ttgaaaacat ttgaaggata
    36361 gaaattggtt ggataaatgt ataaattact tcaccaaaaa ataatgacaa aaactgtaac
    36421 taagttgtaa taaaatggta gttatttagc ataaaataat gtatcataga agtatattat
    36481 aaaattaata aaataagatt tttgtaagaa aactgctggc ttttgatatt tagagtgagt
    36541 agttaaatta tgtttaggag gagtagaatt tgttgcaaaa agtattatgg aaatttttaa
    36601 agctagtagt cggtttattt atatgttcag ttggtatagt attgacgata aattgtaacc
    36661 ttggattatc tccctgggat gtatttcatc aaggactttc aaatcatata ggaataacta
    36721 taggaactgc ttctataatt gtaggctcta tagtagttat tgctgatgtc gttcttggag
    36781 aaaatgtagg atggggaact gtttttaaca tgctactaat tggatttttt atggatttac
    36841 ttttatatag taatttaatt ccagaggctg ataatttatt tgtaggaata attatgttga
    36901 tattaggatt ggttcttttg tctgttggaa tggtatttta tatgggaagt ggtttaggaa
    36961 gtggacctag agatggtttg atggttgcaa ttcaaaagaa aacaggaaaa tcacttaaat
    37021 taataagagg tactatagaa gttggagcat taatagtagg atttttatta ggtggaaaag
    37081 ttggtatagg aactataata agtgcatttg gattggggta tttcacacaa atggtatttg
    37141 gcttatttaa attagattgt agtaagatta aacatagatt tatagtagat gatataaaat
    37201 ttatcaaagt gtatatgagt ggtgagaaaa aagctgctgt tcaaaatata gttaagtaat
    37261 ttaagaataa attcaacgaa atgttaagta ttttaaatta acattttgtt tagatagata
    37321 aattgaatat taaaagaata ttaaaatatg aggattgcta gaacactata aaatatagat
    37381 ttctagcaat tttttatttg ttcaatattt ttttagtact agaagtctta ttctctattt
    37441 aatgaatgaa ttaatttata attagagata ctaaacttta tagatattaa tataaacacc
    37501 tttaaactgt gtattttcca aagcctttaa aatgcttgta tttattctaa ataaaaaaat
    37561 aaaaaaatgt caaaaaaact cttgtattat atccaaattt tatatataat tacctatgtt
    37621 gtttagaaat tttaaactca atgtttagta aacaaaatgt ttagtaaaat aaaacagaaa
    37681 ctaggaggtg caacatggat ataggtgaaa agataaaaag attaagaaca gaaaaacaac
    37741 tgacccagga agagttagct aatagatgtg aattgtcaaa gggatttatt tctcaattag
    37801 aaaataactt aacatcacca tccatagcta cccttataga tatacttgaa atactaggta
    37861 caaatttaag ggaatttttt aatgaaatag atgatgaaag aatcagtttt acaaaagaag
    37921 atatgtttga aactgaagat gaagatttaa aatataaatt aaagtggtta attccaaatt
    37981 cacaaaaaaa tgaaatggag ccaataataa taacattgta tccaggagga cagtataaag
    38041 aagaaaagcc acatgaaggt gaagaatttg gatatgtatt agcaggttca atatatgtcc
    38101 atataggcga aaagaaaaat aaagtaaaaa aaggagagag tttttacttt agaccgaaag
    38161 caaatcacta tatatcaaac gagggcaaaa ctacagcaaa agtgatttgg gtaagtacgc
    38221 caccatcatt ttagaataga ggtgtttaat aattggtaga aaatataata gaattaaggg
    38281 atatatctaa acattatgaa gaacttactg ttttagataa tttcaattta gatataaaga
    38341 aaaatgagtt tctaacattg cttggaccaa gtggatgtgg aaaaactaca acattaaaaa
    38401 taatagcagg atttgagtat gctgatgatg gtaaagtttt atttgaaggt aaggagataa
    38461 ataatttgcc accatatgaa agacaagtaa acacagtatt tcaaaaatat gctttatttc
    38521 cacacatgga tgtttatgaa aatgtagctt ttggattaaa aattaaaaag actccaaaag
    38581 atgtaataga tgctaaagta aaagaggttt tgaaacttgt tgcactagaa ggttttgaaa
    38641 gacgacaagt tgaatcattg agtggaggac aacaacaaag aattgcaata gcaagagctc
    38701 tagtcaatga accaaaggta ttattactag atgaaccact tggagcactt gatttaaagt
    38761 taagacaaga gatgcaaata gaattaaaga gaatccaaaa aaaattagga ataacatttg
    38821 tttttgtaac tcatgaccaa gaagaggctc ttactatgtc agatactatt gttgtaatgt
    38881 ataagggcaa aattcaacaa atgggaacac cacaagatat atacaatgaa cctaaaaatt
    38941 catttgtagc taagtttata ggtgaaagta acatatttga tggaattatg atagaagatt
    39001 ataaagttaa tttctgtaat agagattttg agtgtgttga taaaggattc gaaaaaaacg
    39061 aaaatataga agtagtaata agaccagaag atataaaaat ggtaaagcca gaagaaggaa
    39121 tgttaaaggg gaaagttaca tctacagtgt ttaaaggagt gcattacgag atagaattga
    39181 atgaaaatgg aagattgtgg atacttcata atactaaaaa tgctgaggtt gggactgaac
    39241 taggcatgga tatatatcca gaagatatcc atataatgag aaaagagaat aactaagatg
    39301 aaaagaaaat cttttttagc atatccatat gtagtttgga gtgcgatatt tgtaataatt
    39361 cctttaatat tagtagtatt ttttagtttt acaaaagaat caggtggagg ttatgccttt
    39421 acacttgaga attataaaga agtaattgac cctatatata tgaaagtttt tgggcgttct
    39481 attcttttag caggaggagc tacattaata tgccttatag ttggttatcc agtggcatat
    39541 ataatttcaa aggctcgtgt aagtagaaga ggttcattaa tattattgtt tattcttcct
    39601 atgtggatga actttctttt aagaacatat gcatgggttg ctatattagg aaaaaatgga
    39661 cttttaaata catttttagg ttggtttgga atacaaccat tagcaatttt gtatactaat
    39721 tttgctatac ttttaggtat ggtgtataac tttttaccat ttatggttct tccaatatat
    39781 acagcactat caaagatgga taatgatttg ataaacgctg ctcatgactt gggtgcaaat
    39841 aatatgacag tttttagaaa aattatattt cctttgagtt tgccaggtgt aatgtctgga
    39901 ataactatgg tatttatgcc agcagtcact acttttgcaa tatcaagact gttaggtgga
    39961 ggtaaaataa tgctggttgg agatttgatt gaacaacagt ttacagttgt tggagattgg
    40021 aactttggtt cagctatatc gatatttatg atgatagtaa tattaatatc tatgtctata
    40081 atgtcaaaat ttggagatga atctgacaaa gaaggcggtg ggttactatt ttaaaattaa
    40141 agaaaataac ttctaatata tatttagcat tagtattctt atttttgtat gcacccatat
    40201 ttgctttggt actattttct ttcaatgatt caaaatcaat ggcaagatgg aatggattta
    40261 catggaagtg gtatggtcaa ttacttcaaa atgagagtat aatgagtgct ttatattata
    40321 ctattgtaat agctatatta gcgtctgtaa tatctacaat agtaggaact ataagtgcta
    40381 taggaataca taagatgaga ggtaagagta agaaattaat actaaatgta aactatcttc
    40441 ctattttaaa tacagagata gttacagcag tagctcttat gagtctgttt gtatttgtaa
    40501 aaatggaatt tggatttaca acaatgctat tggcacatat aatgttttgt ttgccatacg
    40561 ttatactttc agttttgcca aaaatgaagc aattacctga taatatagaa gatgcagcta
    40621 tggacttggg agcaacacct atatacgctc ttagaaaagt aattttacca caaataaaac
    40681 caggtatagt ttctggattt ttaattgcat ttactatgtc aatagatgac tttataataa
    40741 gtttctttaa tgctggaaat ggtgtaagca atctttctat agaaatctat ggaatggcta
    40801 gaagaggtat aaaacctgaa ataaatgcat tatcaacaat aatgtttgca gtggttctag
    40861 gtttactttt actagctaat aaaaaagaat ctatagtaag ggggattaaa taatgattaa
    40921 gtttaaaaaa gcaatatccc ttatagctgt aggtatgatg acagttactt tatttacagg
    40981 atgtaataaa gcaactgatt ctacaaaagt tttaaatgta tataatgttg gagattatat
    41041 agatgagtct cttatagata agtttgaaaa agaaacagga atagatgttc aatattcaac
    41101 ttatgatact aatgaaatga tgtatcaaaa agtaaagagt ggtagtacac actatgattt
    41161 agtatttcct tcagactata tggtagagaa aatgaaaaat gaaggtcttt tggaaaaatt
    41221 agattttaag aatataccta atatgaaata tttagataag agttttttaa atcctgtata
    41281 cgacaaaact aatgaatata gtgttgcata tatgtgggga actcttggaa tattgtacaa
    41341 taagaaagaa gttaaagacc ctatggatag ctggaatata ctttggaatc caaagtataa
    41401 gggaaatata atgatgtttg actctgttag agatactata gggataactc ttaaaaaatt
    41461 aggatatagc atgaatagtg taaatccaaa agaaataaat gaagctaaaa atcttttaat
    41521 gaaacaaaag gatttagtat tggcttatgt aaatgatgaa ggtaaggata gattgcttgg
    41581 tggagaagtg gcaatgggta tgctgtattc tggagatgca gttacactaa tggagcaaaa
    41641 tcctgacctt gattatgcta tacctaaaga gggaactaat aaatgggtag atgctatgtg
    41701 tgtacctaca acagcacaaa ataagaaaga agctgagctg tttataaact ttttattaga
    41761 cccagagaat gcaaaagtaa atgctgagta cattgggtat tcaacaccta atacaggagc
    41821 actaaaatta ttagacccag aaataactca gaatcctgtt gcatatccat ctaaagaagt
    41881 acttgataaa tgtgaaactt ttgaagatat tggtgaaaat ataaaattat atgacaaggc
    41941 ttggatagag ttaaaatcaa aatagggtct tgttgtttta agtaaattta cttaataaat
    42001 acttaataaa actgttcttt tttagaaaat ttattttcta attattgaac agttttattt
    42061 tttgtttaag ttatattcat atgcaattta aatagtttat taataaatga aaacttattt
    42121 gtataatgac tttaataata attagaaaaa atgggcaact taatagaata attggaggtg
    42181 taaatttata aaaaatgaat aggataaata aaaaaataga tttattaata ttggctttgc
    42241 tcgtttttat atttttaatt gttggaatag taatactatc gattaggaca gaaaataaat
    42301 tgaatgtgtt cataatgtta gcaataattt tttttataat aatgttaact tatttatcaa
    42361 attcagtagt ggggttgata acaagttcaa taattatatt tatgtataca tcctatattt
    42421 tatataacaa tattactcac aatatggatg ttgaatttat atcatatatg tggataatag
    42481 caacaccagt atcttcaatt ataatgggta atctgaacaa aagcataaat gaattgcaaa
    42541 atacaaataa aaaactatct gaacagtata aggaattagt gactattgat agtgaaactg
    42601 gacttagaaa tttaaagatt ttttataatg atgtaaatat ggagataagt aaatctatta
    42661 gacataatac tgatttttct cttatgatag taaaattacc atactacgga aacctacaga
    42721 ctatatttgg tgaaaacaaa actaataaaa tagtaaaata tattggttca aatattatag
    42781 aatgtacaag aaatgaagat ataatttata gtttacaaaa agatatgata gggatactaa
    42841 tgccaaatac atctttggaa ggttcaaaag ttgttaaaga cagaataaag aaaaggataa
    42901 aagaattaaa tttagattta aacaataggg gaaaatatgt aaatatagat gtcaaaattg
    42961 catttttaca atataagagt agttttggag atagtataaa ttttaagaat atagttgaag
    43021 aggaacttca atatgatgtt taaaatattt aataaaagtc tattaaaatt agtagttgta
    43081 ttatcaatag tactgacaat atcaaatttt agcttatctt catatgcatc agaaattact
    43141 tccagcacag ataaggtatt aatcatatat gattctaaga aagaaacagc ttataataga
    43201 gatattttaa atattatgag gactctattg ggaagattta gttcagatat agagctatta
    43261 aaattgagta actatgatgg tgagataaat aaaaattatt acagtcatat atttatttta
    43321 ggaatcaatg aaaactcata taataatgat aaaaacacta aaaacttgat tagttcctta
    43381 aattcatata aaggaactat atgttggtta ggatatggta tagaaaatct tttggaacat
    43441 aaaaaataca atttagacta tgtaggaaaa acaaacaata tagttagtgt aaattataga
    43501 ggtaaatcat ataacttgga tgaacattat gtttttaaca ttgtagaatc aaaagataca
    43561 agtaataaag taataggaag tattaatgat accttaaata agtatccata tataataaat
    43621 gataaaaatc ttttttatgt atcaaaatta gatttagatg gagttttatt ttatatattt
    43681 tgcgattcac ttaatgatat ttttaatatt aagacgtttg ataaaggacg tatatttgta
    43741 agaatagaag atgtacatgc ttttagagaa ccaaaaaatc ttgtagagat agcggattat
    43801 ttaagtagta agaatatacc atttacgatt gcattaatac cagcatatgt aaatcctaaa
    43861 aatcataagg taataacttt atcagaaagc cctgaaattg tcaaagcaat aaaatatatg
    43921 caagataaag gtggaactgt gatattgcat ggatatactc atcaatacaa gaaagaagaa
    43981 gtttctggag aagggtatga attttgggat ggtaaaaaag atgaaccctt aaaagaaaat
    44041 atgaagatat ttgtcaaaga tagagttttg aatggtctta gagtatgtat agagaatgga
    44101 atttatcctc ttgcatttga agcgccacat tatgcaatgg aatcagaggg atataaagaa
    44161 ttaaaaaaat atttttctac ttatatgggg caacatcaaa ataatgataa aaaatttagc
    44221 acaaatacat atccttatat tattagggat acagaggagt ttaatatatt tatacccgaa
    44281 aatttaggat atatagaccc agaagataag tttacttttc aaaatataaa agaaaattta
    44341 aataaattat ccattgtaag aggttttagt ggagggttct tctttcattc atatttaaac
    44401 atagagtatc taaaaaacac aatagaatat ttagaaaaac agaatataga atttatgaat
    44461 ttaagagatt ttaataattg ggtaaaagtt gatgaaatac aaataagaaa taatggagat
    44521 gaaattatag tcaactatga taaggactta gatgaaataa ctaaaagtga tactagattt
    44581 aaatccatat ccaatattag taaagtttta atattcatag tatctataag tgttttaata
    44641 tttgtgatta tatttatata ttttaagaga atagataaaa agaaattttt aaaataaatg
    44701 attttatatt agaatcaata ttttaaaata ttttaggaga aatttatgag agatttaaat
    44761 gtatcagagt atttgttcgt atttagtctg tttagtatat ggtctttatt gcttataaat
    44821 attattttag ctatgggtgg atatatattt tattttaaaa actttgataa agaaataaaa
    44881 gaaattgatg aatatcctat gatatcaata cttgttcctg ctcataatga agctaaagtg
    44941 ataggtagaa ctgtggagtc tttgctatta ctcaattatc ctaagagtaa gatggaactt
    45001 attgttataa atgacaattc ttctgataat agtaaagaaa ttttagaaaa tataaaggat
    45061 aggtacaaca attataattt cactataata aatacagata gtttaacagg tggaaaagga
    45121 aagtctaatg cattaaatat tggatatacg atttcaaaag gagattttat agctgtttat
    45181 gatgcagata acacaccaga taaaaatgca cttagatatc tagtacaaac tatagtaatg
    45241 aatgatgaat taggtgctgt tattgggaaa tttaggactc gaaataaaaa taaaaaccta
    45301 ttaaccaaat ttataaacat agaaacatta agctttcaat ggatgtcaca agctggtaga
    45361 tggcaacttt ttaatctatg tacaatacca ggaactaact ttatattgag gagaagtatc
    45421 atagaagaaa ttggaggatg ggatagtaaa gcaattgcag aagatacaga aataagtttt
    45481 aggatatata aattgggata caagataaag cttgtaccac aatctataac atgggaacaa
    45541 gagccagaaa ctgttaaggt gtggataaag caacgtacta gatgggcaaa agggaatata
    45601 tatgtattaa tgaaatatat aaaaaatata tttaaacagg gaagaaataa gattgtgttt
    45661 gatatagctt actttttttc tgtatatttt ctatttttaa catctgtaat tatatccgat
    45721 attttatttg ttttaagtat atctaaacta gtagaaattt ctattccaat taactttttt
    45781 ctaatatgga tactatctta tcttttattt attatagaag tgagtataag ccttactata
    45841 gaaaaaggtg aagcaacaat tgaaaatata ttcatagtgg caataatgta ttttacatac
    45901 tctcaactat ggctgtttgt agctataaaa ggaatgatag agtatctaaa agatataatt
    45961 tttaaaagag aggttaaatg gtataaaaca gaaagatttt gattcatgta caggaggaat
    46021 taacatgaaa aaatttatta tatcaattat atctttagta ttgttttttt caaatatatc
    46081 acttatatac aaagtaaatg ctgatgagac taaagttaaa aattataagt ttgaaagaga
    46141 tataactatt gatggtgtta taggaagtaa tagtactttt tttgaagtaa ataaaaattg
    46201 ggatattgaa gaagttttat tgcatcttaa ttttagtaag agccaaatat taaatggaga
    46261 tgtttcaagt ttaactgtat tgataaataa tgtaccaata aaatctatta aattaaatgc
    46321 taagacaaat tataaaaata cattagaagt attagttcca aaagattata taattcaagg
    46381 atataatgaa ataaaaataa aaacatacaa aacaatatct gataaaattt gccaagatga
    46441 ttccaatact gggaactgga tggttattca caaagaatca tatatatcaa ttagatataa
    46501 gcagaaaaag gtggaaaact caataaatga atatccgtat ccatatgcag aaattgaaaa
    46561 taatcataaa ttagatacaa ctatagtagt accagataat atgactagag gagagactac
    46621 agcagtgttt aatttggcat cagcatttgg aaaaataaca aaaaatgatg atttaaagtt
    46681 agatgttaaa ttatattcag aaatgaaaaa ttggtcagat gataatatta tatatattgg
    46741 taaacctgaa aatacagcag aagaaatttt ggatatttta agtataaagg aacaaaccct
    46801 attatcttca aactgtataa tcaagcaagt agattcacca tacaataaga ataagaagat
    46861 gatggtggta attggtagta atgaagatga tttaataaag gcatcaaatt tattaataga
    46921 aaatagactt tctaaccaag ttttatcatc atcagtactt gtaaacaaag agactaatat
    46981 aaaaattaat agggaacaaa aattaaattt aggtcattta acattaaaag acttaggata
    47041 ttctgacttt ttgttggaag gagcatttaa tcaacaagct ttgtttgatg tcaaaatacc
    47101 aacgggtaag gtattagatg atggttcaaa gattatctta aatttaagat attctgacaa
    47161 tttagatttt gaaaaatctt tagttacagt gtctataaat gatgttattg tgggaagtaa
    47221 aaaattggat aggtcacatt ctaataatga taagttagaa ttaaaaatac ctaaagatat
    47281 agataataaa aactattatc aagttaaatt gacatttaat ttgagtataa aaaattcgaa
    47341 ttgtgttact agagagagta ataatccttg ggcatatgta tcaaataatt cttatttggc
    47401 gttatctatg aaagaaaatg aaaccttatc ttttgaaaat tatccgtatc catttgttag
    47461 agatgatgaa tttaatgatt taactgtgat aatgccagat tattcagggt cacaagctat
    47521 gacttggatg tttagattag gtgttacttt aggtgcgaat ataaattcac ataatggaaa
    47581 tataaatgta attagaggaa aagaatttag tgacaagtat aaggatacta atattgtagt
    47641 ttttggagtg ccacataata attctgttat aaagatgtta aataataatt taaatataaa
    47701 attcgataaa aattactcca attttatatc aaatgataag ataagcttta ttgatgatta
    47761 tggaaaaaat atttctacca ttcaattaat aaaatcacca tataataatc aaaaaaatat
    47821 catggtaatt agttcaatga atgaaaaaaa cttatattta ggaatggatt atttgttgaa
    47881 taaaagtaaa gttaatgatt taaaaggaga tacattgata attgatgaat acggagaggt
    47941 agaagattta gcttataatt taaaatctaa gaaagaagta aaagattcaa gttggaatat
    48001 gagtataaat aagacaacta aagtattttt aatgatttct tttattacta taattgtagt
    48061 catgatatta tcaatgctat atataaaaaa atataaaaga agataatatg ataaattt
//
LOCUS       DAMJVG010000023        47752 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.023, whole genome shotgun sequence.
ACCESSION   DAMJVG010000023 DAMJVG010000000
VERSION     DAMJVG010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 47752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47752
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.023"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            121..309
                     /locus_tag="PC512_001425"
     CDS             121..309
                     /locus_tag="PC512_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HDF2441181.1"
                     /translation="MAKVCSVCGKGKVSGNQVSHSNKHNKRTWSANLRSVRAIIDGAP
                     KRVKVCTRCLRSGKIERA"
     gene            complement(469..621)
                     /locus_tag="PC512_001426"
     CDS             complement(469..621)
                     /locus_tag="PC512_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate translocator"
                     /protein_id="HDF2441182.1"
                     /translation="MRNNKSKVLLGILCLATGMAVILSMLLPGWIWSALTALILIGCG
                     ALLFFC"
     gene            complement(719..1195)
                     /locus_tag="PC512_001427"
     CDS             complement(719..1195)
                     /locus_tag="PC512_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HDF2441183.1"
                     /translation="MNLKRSNEKREEYRRMYSDKESFLSLIQNFTSVSIAKELTLKNI
                     ELETSFICEYKGKEVDIIYKVFSKSGKVSHYIVLEFQTEMDTEIVPRLKSYREQIWKS
                     FIMKKSLEEIEDKNFKLPKVIPVVLYSGPERLSRKKGILDIVESISEFSNNSSMKN"
     gene            1414..2175
                     /locus_tag="PC512_001428"
     CDS             1414..2175
                     /locus_tag="PC512_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2441184.1"
                     /translation="MEYTVQKLSKLAGISTRTLRYYDEIGLLKPLKINSSGYRIYGQN
                     EVNKLQQILFYRELGINLENIKNIINSPNFDSLSALKEHHNKLLAKRKQIDLLIENVT
                     KTIALKEGKYTMTDIEKFEGFKEKMIDENEKNYGTEIREKYGKDIIDTSNKKLKNMSK
                     QDYENWQNLNIEIISKLKKAFKTGDASSELAQEVAKLHHKWLSYTWNTYSKEAHSSLA
                     QMYVYDERFTSYYDREQPGLAKFLRDAIVIYTRDK"
     gene            complement(2435..4363)
                     /locus_tag="PC512_001429"
     CDS             complement(2435..4363)
                     /locus_tag="PC512_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF2441185.1"
                     /translation="MHKRLLTLFKLLNESDDKITCKTLSNHLKVSERTIRNDITSING
                     TLEKNGAIIKIKKGEGYYIDILNLALYQQYLALISDDIMDSSEIPDSPIERNQYILKY
                     ILYNNTYIKLEDLANSLYVSKFTILNDIKRIKPILSKYNLILVSKPYYGVKVEGKEID
                     IRRCISNNMINRNFENYIIGITDREIELFNNVDLIELQRVVLSEINKFNINFLDFNLK
                     NFIIHLAITVSRILDGYCLDNVLDVVLTDFQSNTTVENIFNYIESKYTIIISKADRVY
                     LYNHFITKSSLLDNVSNRVDTKIIEYVEEILEVINNQYTFDLRNDSVLFDDLVLHFKS
                     ILNSKSYNLNKVNPLINTIKSNYPLAFEITLNAIEKVFKNSIYSLTEDEIGYVSLHIG
                     AGIERFFQSNIKCKNVVLVCGSGYGSSRLLEVQLNKVFHDKINILQCLSFNQFLASEL
                     SDVDIIISTIPLNHDSIPIVLVDLKLLKKDIENISKSITNNSHIYSNLLDNFFDKNLF
                     IVNPKIKDKDELIKLMCNKLTQSEIVFPSFAESVFYRESLSSTNIDDFLAIPHPMELS
                     SIRTKICISILDEPIYWSEDSTVKLIMMLAINKDDYIKINSIYDILLKIIHDNDIRDS
                     ISNCNDFDNFLSIIKSIV"
     gene            4597..5049
                     /locus_tag="PC512_001430"
     CDS             4597..5049
                     /locus_tag="PC512_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2441186.1"
                     /translation="MVLQEKYIFIDKDLKSKEEVLNFIADSAYILGITTNKEALLKDL
                     LKRENEFPTGIKDGFAIPHTKSVNVKEASILYIKTTNELEWKTLDDSKVRYVFSLLAP
                     HKNEGNIHLKTLSKLATCLMEDDFTNEVKNASDASHLVKYITNKMKEE"
     gene            5052..5360
                     /locus_tag="PC512_001431"
     CDS             5052..5360
                     /locus_tag="PC512_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HDF2441187.1"
                     /translation="MKIVAITSCIAGLAHTPMAAKALEQAASKMGHEIKVEQQGAMGR
                     VNTITKEEAQDADFILIASDQTISGMERFDGKKVIKVKIGIALKKPEAVLTKCIEAIS
                     "
     gene            5474..6580
                     /locus_tag="PC512_001432"
     CDS             5474..6580
                     /locus_tag="PC512_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HDF2441188.1"
                     /translation="MSKKNKSLLSELKGHLMTGISYMLPLVIGSSLVVAIPKLTALAM
                     GITSLDAYKNVSGFYHILYLMEQVGWTGIGLLNTVLAGFIAFSIGEKPAMGAGFIGGL
                     IASNTNAGFLGAVIAGFFAGYVCKFLKKKIKISGSASGMMPLIIMPLITVGLTGFLMS
                     VVLAGPLGNINTSLNAWVAEMCQNGTNSVVLALILGAMIGFDLGGPVNKAAWMAGNAL
                     LLEGIYLPAILVNCAIVIPPLGYGLATFIRKSKFSNALAETGKGNIVMGIIGITEGAI
                     PFTLTNPLKLVPVNMIGCALGVGLSALLGVHAIMPPVGGLYGFISIGSGWAYLVGAIF
                     GALVIAILSTTLVDFNEDETTENTEFDEIELDIM"
     gene            6655..9333
                     /gene="mngB"
                     /locus_tag="PC512_001433"
     CDS             6655..9333
                     /gene="mngB"
                     /locus_tag="PC512_001433"
                     /EC_number="3.2.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosylglycerate hydrolase"
                     /protein_id="HDF2441189.1"
                     /translation="MKKTKVHVVPHSHWDREWYFTTSRSKIYLMKDFQDILDILEEKE
                     DFKYFTMDAQASLLDDYLKWRPQDEYRIRDLVQRRRLVIGPWYTQTDQLVISGESIIR
                     NLYYGIDRCNEFGEPMRVGYVPDSFGQSAQMPQIYRGFGIDSSLFWRGVSDDMVDTTE
                     FIWKGSDGSKVLAVQIPFGYYYGGNIPEDDSDLKEYLKDIIGKLKVKASTNNVYFPNG
                     FDQAPIRKNLPDILKKANEIDNENEYEISDIENYIDSVRNERNEFTELKGEFLNAKHM
                     RIHKSIFSSRSDLKIMNNKLENYITNVLEPLLTLSYSLGNEYPHLVIKDIWKLMFENA
                     AHDSIGSCNSDTTNEDVYTRYKQARDLSINLLDLHMRLISTQIKNNNEEITLTVFNGF
                     PEVRNEVVEFDTYIPGQDFVIKNKNGKILNYIIKEKEDITNYILTQTIRLNPSKKIYI
                     PKTVYRAKIALSVKDIPPMGYTQLVFELDTKNKCEIETSNCKEIENKYYKITANKNGS
                     LEILDKESNKTYKNQAVIEDNGDDGDSYNYSPPRKDIYVSSLDSVSSVEVLKSNIQEE
                     MILKYSLTIPTSLEERAIGKVSVKMPVTMKITLEPKEQIIKFNVNIKNNQALSHRVRV
                     LFNTEIASKFSIADQQFGIIQRPTVLEKDLALWKRDNYSWQEKPITIEPMQSFVTLED
                     GQRGIALITGCVREYQIVGDNLDTIALTLFRSFGYMGRENLLYRPGRASGEKIIATPD
                     AQLLKELNFDFGLYIYNNKFDEANVANTAKRFLTPIQIYEYADFLNGRLIFAFNDEKQ
                     IYENEFSLMNVNNSNFTVSAIKKEEKGDGIVVRIFNGMKNEDAKGSLNINKNVNDAYS
                     AMLDEIYDNTSKLKVNTKTVEVNSLSHCKVQTIVIK"
     gene            complement(9650..11983)
                     /locus_tag="PC512_001434"
     CDS             complement(9650..11983)
                     /locus_tag="PC512_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF2441190.1"
                     /translation="MDTKLKKFKDKYIVTIIVFILMLSASLGMISQYSTIQASAKGGA
                     ENPFEQESFVDSIYKGSYVLYHNMKEEQEGKMIQPSKLFINEETMNYIKNVSKEKDTY
                     DGSETYYTDDSINADFNENFENWEHFIKASGKNLKYYLVDKESNFEFFNDNKELGVLD
                     TTKNDASKENSNENQSKNTEMNDEERQKQITDIKENYRFYVVMNFDKDGKVNIVDSYG
                     VNQKIINQMLLSKAREDLMDTSLGGNSISYKLSPIKNITLVYAVPKVISKGDSVEYGY
                     GNTYFDDGIISYISNVENNSYYKISGMILKIILAIVVIVALAFPYRKSKELLGFDTLS
                     RIPLEILFIALAIIQGLVDLYPTVIISNTLSGNYVEYLINNDISAKMASILVSLMNLT
                     YWFVIFSIIFVFIILLKHILNVGIREYFTKHTVTGMFFVWLKKAGKAVINQIRTINLK
                     EKPNKTIVTILGINLLIIVIMCSMWFFGIILALIYSVVLFKILSDYSKKTIYEYNQLL
                     DVTKKISDGNLDVNMEKDLGFFNPIKDELGNIQTGFKKAVDEEVKSQKMKTELISNVS
                     HDLKTPLTSIITYIDLLKDESITDENRKLYIDTLDRKSQRLQHLIEDLFEVSKANSGD
                     VYLNIVNVDIVSLMKQTLLELDDKLADSSLIVKNNFSNEKIILPLDSQRTFRVFENLI
                     INISKYAMPNSRVYIDILETDNKVNIMLKNMSASEIDFSVDDIMERFVRGDKSRNTEG
                     SGLGLAIAKSFIELQGGKMNISVDGDLFKVTITFNKN"
     gene            complement(11958..12674)
                     /locus_tag="PC512_001435"
     CDS             complement(11958..12674)
                     /locus_tag="PC512_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2441191.1"
                     /translation="MNSYNILVVEDEKEIADAIEIYLLNQGYNVFKGYNGLEGLKVIE
                     NQEIHLAIVDIMMPKMDGITLTMKLRENYNFPVIMLSAKSEEVDKIMGLNIGADDYVT
                     KPFKPLELLARVNSQLRRYTKYLNMVGNKEQKVESDDSVFAIGGLELNENTKEVSIDG
                     KYIKTTPIEFKILSLLMRNAGRVFSADEIYERVWNENAVNTDTVMVHVRNIREKIEID
                     PKNPKYLKVVWGVGYKIEKI"
     gene            complement(13089..13745)
                     /locus_tag="PC512_001436"
     CDS             complement(13089..13745)
                     /locus_tag="PC512_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF2441192.1"
                     /translation="MELQDTIFKRQSVRKFKNQDVSDEDILKMIKAAGAAPSGKNIQN
                     WHFVVIKRRDLMEKIADVITKKQQEILVEMDKVSVDKANRFRKFVKNFTLFYLKAPVL
                     VLVFTKVYNPSGYYELELIDAPKETIDKLFIRNPGMQSLGAAIENFTLSAIELGYGSC
                     WLTSQNYAADEIEAVLEAETGFEKGEYFLGAMLALGVPEDNLKSPSKKPVEEICTFIK
                     "
     gene            complement(13800..14429)
                     /locus_tag="PC512_001437"
     CDS             complement(13800..14429)
                     /locus_tag="PC512_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HDF2441193.1"
                     /translation="MVDSIIFDLDGTLWDSTEEVCKVWQDVLSEHKEIELSVTKDLFR
                     SLMGLSFEEIANRLFPNLSEEERMNLLNECSLKECDYLSENGAKLFDDIEDTLKLLSK
                     KYKLFIVSNCQAGYIESFLKAHKLEQYFIDFECPGNTGLHKGENNKLIIERNKLINPI
                     YVGDTQGDANSAKFVGIPFIYAKYGFGNVDVYDYFIDSFKDLLEHDILK"
     gene            complement(14560..15201)
                     /locus_tag="PC512_001438"
     CDS             complement(14560..15201)
                     /locus_tag="PC512_001438"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HDF2441194.1"
                     /translation="MKICIVLNGEIEDYEVTRDIIIKECYDCIICADGGANHTYKMEI
                     MPDYILGDLDSVEEEKINFYKNKGVKFEKFPSKKDETDTELCLFLAKTLKANHIDFFG
                     ALGGRIDHTLANIKLLYYLKEDGIYSRILSDKEEMYIVENEEISLYGNPGDTISVIAI
                     NGDAKGVTLTGLEYPLDNYYMKYSVPIGISNVMLSNSCKIKVEQGCVLVVRNL"
     gene            complement(15210..15881)
                     /locus_tag="PC512_001439"
     CDS             complement(15210..15881)
                     /locus_tag="PC512_001439"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HDF2441195.1"
                     /translation="MIKLAPSILSADFAKLLEDVRKVESAGCEYLHIDVMDGHFVPNI
                     TLGPLVVKSLKKENINMVFDAHLMIENPDQYIEEFVKAGCDIITVHQEACVHLHRTIQ
                     NIKSHGIKAGVVLNPATPVDTIKHVLSDLDMVLLMSVNPGFGGQSFIPCVLDKIKELK
                     AIIDSQGLNIDIEVDGGISPKNVAEVVQAGANVIVAGSAIFGSDDIQETVNLFRKNAS
                     LEELV"
     gene            complement(15886..16770)
                     /gene="rsgA"
                     /locus_tag="PC512_001440"
     CDS             complement(15886..16770)
                     /gene="rsgA"
                     /locus_tag="PC512_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HDF2441196.1"
                     /translation="MLEGKIIKGISGFYYVDTYNGIYECKARGIFRKQKITPLVGDRV
                     KISIVDEDEKKGILEEIDSRDTELIRPPIANVDKALIVFAIKNPKPNLSLLDRFIVLA
                     EKENLETVIILTKADLDDNDTLETVKNIYELSGYKVIPVSNITKLNIDKVKEELKENV
                     VVFAGPSGVGKSSLLNEIDENFKLQTGVVSDKIKRGKHTTRHAELLKLEFGGMVADTP
                     GFSSLALEDIEEVELKDYFIEFDKFNDCKFGSKCIHENEPNCAIKEAVTNGEISKERY
                     DSYIQLLHEIRQNNSRRY"
     gene            complement(16868..17605)
                     /locus_tag="PC512_001441"
     CDS             complement(16868..17605)
                     /locus_tag="PC512_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDF2441197.1"
                     /translation="MKKKTVLITGGARGIGKAMSKAFAKEGYNVLVNFNKSENEAKEL
                     YTILNEKNFSVKLFKANISNREDVEDMVDYCIKEFGGLDVLVNNAGVSQDKLFTDITD
                     EDWDNMMNINLKGSFYCSQVALKYMISEKKGNIINISSIWGISGASCEVHYSITKAGI
                     IGMTKALAKEVGPSNIRVNSIAPGVINTDMLSGYNEEDIDALVEETPLMRLGTPEDIA
                     NCAIFLASDKSNFITGQVISPNGGFVI"
     gene            complement(17713..19728)
                     /gene="pknB"
                     /locus_tag="PC512_001442"
     CDS             complement(17713..19728)
                     /gene="pknB"
                     /locus_tag="PC512_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HDF2441198.1"
                     /translation="MGDTILGNRYEIIRKIGDGGMAFVYEAKDRLLNRTVALKVLRPE
                     FVDDDEFLTKFKREAEAVASLSHPNIVNVYDVGEDGKVHYIVMEFVDGKNLKEIIQDE
                     GILDEYTALDITKQIAMALSAAHKKGIIHRDIKPHNILISNEGRVVKVADFGIAKAVS
                     NSTMTNIGSIIGSVHYFSPEQAKGKFVTNNADLYSLGIVLYEMLIGKVPFRGDSPISI
                     ALQHINDDIDFTSEEKVRIPQSVRTTIKKLTEKSSADRYQTAEELIEDIEYIEKNIDL
                     DFIKEYDDFATKKIDEKEINKVVNPTLAKPAPEKVVKPVEVADLDDDEDYYDDFYEED
                     DDEDEEEEEIMRAKKNQRPKSTPSKRTKKKKKKQESPKSRRRLKVIAAVLILILCAQV
                     FLAYKFLFAGGFGNKSLTVPNLVNMTLEEAQSAVEKEGLYLSVKSEEYNSEVDENCII
                     SQTPEGGSTNVKKGDTINVVVSKGSSQASVPNVVGLTLSNAKQLIEENNLKVGTVKYE
                     YSSIYKEGTVLSQSPGAGSSRAQEGDEVNLYVSKGSEKSNTQTPTVPDKKPTTPENNT
                     PTEPGSNSGNSGGNSGGSNSGNSGGNSGNNGSNSGGSNSGNSGGNSGGSNSGDNGGSS
                     GGSNSGDNGGSSGGSNSGDNGDSSGGSNSGDNGGTSSGTGANIGKTE"
     gene            complement(19745..20497)
                     /locus_tag="PC512_001443"
     CDS             complement(19745..20497)
                     /locus_tag="PC512_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HDF2441199.1"
                     /translation="MVYSCASHIGKIRKNNEDYCEGEVIDTEHGPIGIFAIADGMGGH
                     KKGEVASKLAVENIIDFLKENLLQHDNVKIDYIDDILKQAYNNVNSIVHKKSMEDIEF
                     EGMGTTLVTAIVYNNVLYVANVGDSRCYLLTDEKFDKITIDHSVVEELMMAHVITEEE
                     ARRHPQRNRITRAIGTDDMVVVDIFKKEIKKSDIILLATDGLTGFIDDEDIRDLILDY
                     EYERTSNISEELISMANDVSGKDNVSVIVIKV"
     gene            complement(20517..21548)
                     /gene="rlmN"
                     /locus_tag="PC512_001444"
     CDS             complement(20517..21548)
                     /gene="rlmN"
                     /locus_tag="PC512_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HDF2441200.1"
                     /translation="MEKKKIVLKNFTEDELKEFMKTIDEKPFRGSQIFSWIYKGAKTF
                     DDMNNIPKSLRNKLEEVSCIGHIDIELKLESKVDNTKKYLFLLDDGNIIETVMMDYDS
                     RVTVCVSNQVGCRMGCNFCASTMDGLIRNLEPWEILDQVIKIQEDTGKRVSNLVLMGS
                     GEPLDNFENTKQFLKIINEKNGLNIGYRHITLSTCGIVPKMYELADLEIAINLALSLH
                     SPYDEERRKIMPVANAYSIEEILNACRYYIKKTNRRVTFEYSLIKGVNDSEKEAKALA
                     KLLKGMLCHVNLIPINKVEEREYEKPDKAFIYKFRDSLEKNNIPATVRMSMGSDISGA
                     CGQLRRKYK"
     gene            complement(21556..22881)
                     /gene="rsmB"
                     /locus_tag="PC512_001445"
     CDS             complement(21556..22881)
                     /gene="rsmB"
                     /locus_tag="PC512_001445"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HDF2441201.1"
                     /translation="MDAREVGFKVLCDIEKNDNYSNIAINKHFKNLEISDMDRGLATE
                     LIYGVIENKYYLDYIINKLSKIKVKKMSTYVKIFLRMGTYQILFLDSISDYAAVNETV
                     KLSKKYDKKSSGFINAILRNEIRAKETIMDITEEDSVKYLSIKYSYNSWIIKNWIDKF
                     GQEFAEDLLEANNEKPSIYIRTNTLKISREELIEKLSEMGIVCLKVPMVEEAIKVEKM
                     KNIEKNELFKAGLFTIQDISSMIVGKVINPKEGSFVLDVCSAPGGKSTHLATLMNNTG
                     QVVARDIFEHKLKLINSTVNRLGLKNVFVERFDASEIDENSISKFDYVLADVPCSGFG
                     IIRRKPEIKYKKEEELKDITSIQKKILENASKYVKVGGTLVYSTCTIQDVENINIVTS
                     FVEENHNFEFVPIDTVNVDLDNQDKGYLKIYPNIHGIDGFFIAKLKRIR"
     gene            complement(22943..23644)
                     /locus_tag="PC512_001446"
     CDS             complement(22943..23644)
                     /locus_tag="PC512_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HDF2441202.1"
                     /translation="MYPVYGGFWGFDPTMVVLIPAILLTIYAQFKVSSTTNKYLRVNT
                     RRGYTGEQTARRVLDSNGLYDVKIEMVRGHLSDHYDPRRKAVRLSEDVYYGTSITSVA
                     VAAHECGHAIQHAKGYAPLQIRSSLVPVVNFASSISWFLIFLGFIMAGPFLKIGILLF
                     SASVLFQIITLPVEFNASSRAIVQLGNLGIIDESESRQSRRVLSAAALTYVAAALVSI
                     LQLLRLLLIAQRRND"
     gene            complement(23713..24465)
                     /locus_tag="PC512_001447"
     CDS             complement(23713..24465)
                     /locus_tag="PC512_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF116 domain-containing protein"
                     /protein_id="HDF2441203.1"
                     /translation="MTDIKKYLTSVGILILILGILIGVVNFFIISLTQIFSLMINIII
                     ISLILIILCSTVVTYRVIKGKYVNSNIMKINFNIVSGLFPIISFIASSFGMSKSDIRR
                     IYIKLNNEYIYSNKYNFNPEDIIILIPHCIQENSCKLKVTNDIDNCKECGRCNIGELI
                     KLKEKTNVKIFVATGGTLARKIIMDTKPKAVVAVACERDLTSGIQDIKKIPVLGVFNK
                     RPNGPCVNTNVDMMDIEKAIGFLTGKNILVCN"
     gene            complement(24475..25404)
                     /locus_tag="PC512_001448"
     CDS             complement(24475..25404)
                     /locus_tag="PC512_001448"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HDF2441204.1"
                     /translation="MKIVFMGTPDIAVPCLQKIIDEKYEILGVVTQPDKPKGRGKKLG
                     MSPVKELAIENNIPVYQPVKARDKEFIDKIKSLNPDVIVVVAFGQILPKEILEIPKLG
                     CINVHVSLLPKYRGAAPINWVIINGEEKTGVTTMYMDEGLDTGDMILKTEVNLDENIT
                     AGELHDKMMNIGAETLKETLRLIEEGNAPREVQNHEEFSYAPIMNKSLGNIDFSKSAR
                     EIHNLVRGVNPWPSAYTTYNDVIMKVWKTKVLDEKSTKDVGTIIDVSKDGIKVSTIDN
                     VLLIEEIQMPNKKRMLVGEYIKGNTIETGLVLG"
     gene            complement(25419..25859)
                     /gene="def"
                     /locus_tag="PC512_001449"
     CDS             complement(25419..25859)
                     /gene="def"
                     /locus_tag="PC512_001449"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HDF2441205.1"
                     /translation="MALRQIVQIGEPVLRKKSKKVEKIDEKIIQLLDDMAETMYDADG
                     VGLAAPQVGILKRVVVIDIGEELIELINPEIIETSGEQIDEEGCLSVVGEAGNVRRPN
                     YVKVRALNRNGETIELEGEELLARAFCHEIDHLDGILFVDKIEK"
     gene            complement(25877..28402)
                     /gene="priA"
                     /locus_tag="PC512_001450"
     CDS             complement(25877..28402)
                     /gene="priA"
                     /locus_tag="PC512_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HDF2441206.1"
                     /translation="MNNILNLSRGFIMKKYAKVIVRSNTIYTDNLFTYQIPVFLSDVI
                     KIGHRILVPFGKGNKPTEAFVFQFTDSLDEKIKIKEIIDILDENPIFRKEDLELVYWM
                     KNRYLCTYIECINLIYPKGYKLNNYKVVLLGESLSGLNDIELKEKISTLSDKNREIVE
                     KVIDSKGKIKVDKLKYIPNLNSSLYTMNKNGIIKLCWEYKNHKNEKKVCYISLSLESD
                     KIDDYIEQNKINVGSKQKEILSFLKNNENVEINDLLDLLNASKQSINSLSKKKLITLE
                     FKDYYREPKSIYKSVLKSIKLNNEQQEAVDEIKSNMFVDDKKPYLIHGVTGSGKTEVY
                     MEIIEFALNQGLDSIFLVPEIALTPQTIDRLKSRFGDLVGVFHSKLSEGEKHDVYKAV
                     KAGKVRVLIGARSALFAPFNSLGLIIIDECHESSYKSEKNPKFNAIEVARFMALKNNI
                     TLILGSATPSIEEYYRAKSGEYKLINIKSRANDKPLPNIEVVDMKDELDKGNRSIFSL
                     KLQKEIRYAIEENNQVILFLNRRGYANFVSCRKCGYVFQCENCDISLTYHKKSNTGRC
                     HYCGYEKEIPKECPECKSTYVKPFGVGTQKIEEELKYIFPDIKTLRMDKDTTSKKGAL
                     DEILNKFKDKEADVLIGTQMLSKGLDFENVTLVGILSADMILNFPDFKSFETTFQLIT
                     QVSGRAGRADKEGKVVLQTYDTEHYAIKHAIEYDYEGFYEDEIKIRKAFGYSPFNNML
                     SVVVSGEDERLVIKNIKNMHASLIYLLEKRGINDLGFILGPNPCSISKINQNYRWQIL
                     FKDENIEINLLKGIIKYICITKRDLIFDKNINVSIDINPNSVL"
     gene            complement(28641..29840)
                     /gene="coaBC"
                     /locus_tag="PC512_001451"
     CDS             complement(28641..29840)
                     /gene="coaBC"
                     /locus_tag="PC512_001451"
                     /EC_number="4.1.1.36"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphopantothenoylcysteine
                     decarboxylase/phosphopantothenate--cysteine ligase CoaBC"
                     /protein_id="HDF2441207.1"
                     /translation="MLKDKTVVIGISGGIAAYKACDVVSKLKKLNANIHVIMTKSATE
                     FVKPLTFQSLSQNYVVEDMFEEPKTWEVEHISLAKKADLFLIVPASANVIGKIANGIA
                     DDMLTTTVMATKAQVLIAPAMNTNMYENPIVQKNIQTLKSFGYKFIEPESGRLACGDI
                     GTGKLANPDIIVEEVLTNLTKEQDLKGQSMIVTAGPTVESIDPVRYLTNRSSGKMGYS
                     IAREAIARGADVTLISGPTNLSIPQNLKKFVQIESAQDLYEAVVSNLSENKIVIQSAA
                     VADYKPKTYSDKKIKKKNDDLSIELSRNYDIAYEIGKIKEDKILIGFAAETNDLIEHA
                     KGKIKKKNLDFIVANDLTKEGAGFRADTNIVKIIDVEGNITEYPKMKKEEVANVILDK
                     VKALLEK"
     gene            complement(29845..30111)
                     /locus_tag="PC512_001452"
     CDS             complement(29845..30111)
                     /locus_tag="PC512_001452"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HDF2441208.1"
                     /translation="MLKPSINEVLEKIDNRYYLVGTVSKRARKLIDGEEPYVSNKTKE
                     KPVCVATKEVASGKITYRLLTEEEIEIEEARHHAEQHQQISEEE"
     gene            complement(30114..30731)
                     /gene="gmk"
                     /locus_tag="PC512_001453"
     CDS             complement(30114..30731)
                     /gene="gmk"
                     /locus_tag="PC512_001453"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HDF2441209.1"
                     /translation="MFVKKGLLLVVSGPSGAGKGTICKELLKENDTIKLSVSATTRKP
                     RTGEVDGVNYFFISKEKFEEMIEKGEFLEYAQIYDNFYGTPKAAIMECLEKGQDVLLE
                     IEMQGAKQIKEVCPEGVFIFVLPPSLEELKNRIVGRGTETEAEIEKRFSCAYEEIKMI
                     KDYDYFIFNEDVKTSAKEIEGIISSEKNKVSRYKNIIIEKFKEEL"
     gene            complement(30761..31642)
                     /locus_tag="PC512_001454"
     CDS             complement(30761..31642)
                     /locus_tag="PC512_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HDF2441210.1"
                     /translation="MAISMTGFGRGEYKDDNYYFLVECKTINHKYSDINIRLPRKISF
                     LEDKVRNLVKNYVKRGRVDLYIKFDLLGKEDVNLNFDEGLASQYIDILKEIKNKFDII
                     DDISVMNVAKFPDIVKIEEKEEDEDLLWSMLNQAVEDALIKLREMRSEEGKKLAEDIA
                     MRCDLLKNHIEEIEKYSSSVVEDYREKLNLRISELLDDPSIIDENRLAQEVAIYADKS
                     SITEEIVRFKSHIGQLKNTIFKDDSIGRKIDFLIQEMNRETNTIGSKSSDINITNLVV
                     EVKSELEKIREQIQNIE"
     gene            complement(31646..32476)
                     /locus_tag="PC512_001455"
     CDS             complement(31646..32476)
                     /locus_tag="PC512_001455"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HDF2441211.1"
                     /translation="MKFWKLHGIGNDFIAIDGRFDQINPSDYTALAKKVCHRRFSVGA
                     DGLLVVKDSKVADVEMVYYNSDGSRAAMCGNGLRCFCKFVYDNCIVKKESFTVDTLDG
                     IKDIKVNLTNREINSIRVNMGKGSFIAKDVPVLTNKERFVQESIKVLDRELKVTSMLM
                     GVPHTVVIVDELDVDDVCKYGKEIENNKIFPEKTNVNFVKVEDKYNIHVYTWERGCGY
                     TLGCGTGMTASAIVCNLLNMVESSVNVTSQGGTVKIDVGDFSYMTGPAVKICEGILEV
                     "
     gene            complement(32763..33797)
                     /gene="ltaE"
                     /locus_tag="PC512_001456"
     CDS             complement(32763..33797)
                     /gene="ltaE"
                     /locus_tag="PC512_001456"
                     /EC_number="4.1.2.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low-specificity L-threonine aldolase"
                     /protein_id="HDF2441212.1"
                     /translation="MRFIDLRSDTVTMPTDEMREAMAKAPVGDSIFRDDPTVNKLEEL
                     AAAKVGKEDAIFLPSGTFGNQLALFTHCLRGQEIIIGKGYHIVTHEVGAPAVIAGVQL
                     RTIDEDESGALNPELVEKAIRRDDIHEPQTGLICVENAYSGGTVVSLDNLREIKKIAE
                     KHNLPVHLDGARLFNAALTLGVEAKEIAKCCDSVMFCVSKGLAAPMGSILAGNKEFIA
                     KARRKQKVMGGGMRQVGIVAAAGIIAIEKMTLRLNEDHENAKYLACELNKIDGIEVNN
                     VNPDISMVFFKMSEDIIKEDVLIKEFFERNIKINKMENGEYRFVTHVDITKEDLDYVL
                     KTLKELIGVC"
     gene            34093..35868
                     /locus_tag="PC512_001457"
     CDS             34093..35868
                     /locus_tag="PC512_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NFACT family protein"
                     /protein_id="HDF2441213.1"
                     /translation="MALDGLVIHSIVDELSSKLTGGKIDKIHQPEDDEVIFNIRNNKE
                     NFRLVLSASASNPRVYLTSNYQKENPLKAPMFCMLLRKYIQGGNIVEISQIGFERIIK
                     ISVESLDELKEKTVKNIMIEIMGRHSNIIITHGEENKIIDSIKRVPFSISRVRQVLPG
                     HDYSLPPEQNKLNPLDDISKDLFIKNLEELEGPIFKSIYSKFLGISPIIAKEICYRAG
                     VNQNAIIKDISDEQFDALHKVFCNLFNDINSNKYSPCIIIDKKVDKVVDFSCINLTLF
                     SDLSYINKDSMSRILEDFYRTKDIKDRINQRSSDLKKSISVKLDRLYNKLKKQEEELS
                     ESENADIYKIKGELITSYIYMVEKGMESIEVANFYDENCNDVTIELNKNLTPSENAQK
                     YFKKYNKMKHAKVEISHQISLNKEEIDYLENIILSIENCENLAELQDIKEELAKVGYI
                     KTQKKNSKKDTIPSTKPHEFVSSDGFKILVGKNNKQNDYLTLRLADNDDLWMHTKNIP
                     GSHVIIKCAGKEVPDNTVFEGAMLAAFFSKSKLSSQVPVDYTKRKNVKKPSGSKPGMV
                     IYETNSTIYVTPEEETVAKLKVKSE"
     gene            complement(36083..37735)
                     /locus_tag="PC512_001458"
     CDS             complement(36083..37735)
                     /locus_tag="PC512_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDF2441214.1"
                     /translation="MLLVKVENLKKYYADKLILDIDKLEILENDKIGLVGSNGQGKTT
                     LLKAILGEIEIDEGYTYLTESYSYISQSENNIETCSHSKEKSLLNAPDKFEEHLSGGE
                     KVKLKIADALSNKKNIIIADEPTSNLDKKSIGVLEDMFKRHEGALLLISHDRRFLDEL
                     CTTILELEDGKLKAYKGNYTDYLMQKDEEVKRADFEYQEYVKEKKRLEKALLYKKALS
                     DGIRKTPKRMGNSEARLHKMGGQTNKKKLDSNVKAIKSRIDKLEVKNKPKVSKEMNIK
                     MQDGMEIISKNLVEVKDMTLKLENKLLLDNVSFKIKRGKKIALLGDNGCGKSTLIKEI
                     LADKNDNIKINNKVKVGYFDQNQSLLDEEKSVLYNTKVNSSFDESFIRINLSLFGFKG
                     DDVYKKVKVLSGGEKVKIALCKIILEDNNFLVFDEPTNYLDIKSMEALEKALINTDKT
                     MLIVSHDRVFVSHICNYIIEIKDAKIREFDCNYDEYTISRNKKTPSRENQIKKENLLV
                     LENRLTTVISMLSIEKDNLKKELYESEYNELLKQINKLKNSF"
     gene            complement(38034..39245)
                     /locus_tag="PC512_001459"
     CDS             complement(38034..39245)
                     /locus_tag="PC512_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HDF2441215.1"
                     /translation="MKKTIMSLQHLLAMFGATVLVPILTGFNPSVAIFCAGVGTLIFH
                     FCTEGKVPAFLGSSFAFIPVILAAKEAYGGDLAYAQGGIIVAGLIYIIMSIIVKVVGV
                     NKIKLYFPAQVTGAMIVVIGLNLLPTAFSMASANFVIAFITLAIAILTNKFGRGFIKQ
                     LGILIAVFSGYIICLILRLVDITTITEASLFAIPNFTVPKFSLGAIVIISPVVLAVFM
                     EHIGDMTTNGAVVGKNFIENPGLNRTLLGDGFATIVAGCLGGPANTTYGENTAVLAIT
                     KNYDPSILRRTAIFAILLACVGKFGGFLQSIPGSVMGGISIMLFSMITYVGLKTIRDS
                     SCVESKINILIIAVILLIGLGTTYLSNKGISVGIPITSTVKITGLSLAAIVGIVLNRI
                     LNNQDFKVEEE"
     gene            complement(39529..40062)
                     /gene="pyrR"
                     /locus_tag="PC512_001460"
     CDS             complement(39529..40062)
                     /gene="pyrR"
                     /locus_tag="PC512_001460"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001156491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HDF2441216.1"
                     /translation="MVEKAQLMDEKAIARAITRISHEIIERNKGVENLVLVGIKTRGV
                     PIANRISKKIEQIEGTKVDTGDIDITLYRDDLEKIHVEPVVKGTYLDFNVNDKTVVLV
                     DDVLYTGRTVRASLDAIIDIGRPKSIQLAVLVDRGHRELPIRADYVGKNVPTSRHEII
                     SVSLLEIDGEDSVTIKE"
     gene            complement(40422..41369)
                     /locus_tag="PC512_001461"
     CDS             complement(40422..41369)
                     /locus_tag="PC512_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HDF2441217.1"
                     /translation="MFYFLKVKVGDIMDEVKEFLVLEEEEEVRLDIYLAEQLGDMSRS
                     YIQKIIKDGKVKVNNKVEKARYLVKEEDNIVIEIPEPKVLEVLPQDIPIDIVYEDDDV
                     LIINKPQDMVVHPAPGNYENTLVNGILYHCKDKLSSINGVIRPGIVHRIDKDTSGLLM
                     IAKNNYAHNFLAEQLKEHTITREYEFICYGVVKEDKITVDKPIGRNPKDRLKMAVVKD
                     GKNAITHFEVVERFDKFTHMRARLETGRTHQIRVHALSINHPLLGDYVYGPKETKFKL
                     KGQTLHAKKLGFIHPTTKEYIEFNSELPEYFKEVIKKIK"
     gene            complement(41338..41784)
                     /gene="lspA"
                     /locus_tag="PC512_001462"
     CDS             complement(41338..41784)
                     /gene="lspA"
                     /locus_tag="PC512_001462"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HDF2441218.1"
                     /translation="MLYILIIILLIGLDQLSKIWVLNNLVDVSTIPIINNVFHLTYVE
                     NRGAAFGLLQNNQWIFIIVALLATVFGLYYLNTRKVHIFGRLGIILIISGALGNLIDR
                     VRLGFVVDYFDFRIIWEYVFNIADVFVVVGTVFLCIYVLFFESKSR"
     gene            complement(42094..42873)
                     /locus_tag="PC512_001463"
     CDS             complement(42094..42873)
                     /locus_tag="PC512_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDF2441219.1"
                     /translation="MKKIIWGICICLLSIVGVYTYNHNTHNQDSSKEAYSLNDNIKDD
                     YEDVIIKKGNEDEKILALTFDDGPDEDFTPQVLDILKKNDVKATFFVVGEKVEYNKEL
                     LKRQYDEGHEIGNHTFTHINVAKNSYSSVEKEITDTQNIIKSVIGVEPKIFRPPYRAM
                     SKSVCDIIVSKGMNIILWSNLDPRDWSNPGVDAIINTILTKVQNGNIILLHDYNTKRN
                     DKSQTIQALEVVIPKLKERGYKFVTVSELIQHLDKNKQVQK"
     gene            complement(42928..43410)
                     /locus_tag="PC512_001464"
     CDS             complement(42928..43410)
                     /locus_tag="PC512_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA C4-type zinc finger protein"
                     /protein_id="HDF2441220.1"
                     /translation="MDTKKYKDKLLKERENLTNLVEDMKDNTLFGDTTKHTSEKYSSG
                     ELSSYDNHIGDMGTDLYMQNMQNSLINHEEGRLYQIDLALSKIENGTYGICDLCHNQI
                     DLERLDILPDTSLCNDCAKKENNLLGDAMQNPDVEDSNFYSEDLTNLTDLNKNGILRD
                     "
     gene            complement(43676..45097)
                     /locus_tag="PC512_001465"
     CDS             complement(43676..45097)
                     /locus_tag="PC512_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation protein A"
                     /protein_id="HDF2441221.1"
                     /translation="MVSFLGSIVVLIVGYFVYGTFVEKVFGTNDKNQTPAIACRDGVD
                     YVPMKWKRIFLIQFLNIAGLGPIFGAIQGALFGPSAFLWIVFGTIFAGGVHDFASGYL
                     SMKNKGTSASELVGLYLGNGAKIAMRIFSVILLVLVGVVFVTGPAGLLKTLTGVNAQI
                     WVGVIILYYIMATVLPIDKLIGKIYPLFGAALLIMAVGVAGGLIIKGYNIPNINLQNM
                     NPNGTPLFPYLFITIACGAISGFHATQSPLMARCVEKESEARPVFYGSMVAEGIIALV
                     WAAAAMSYFHGIPQLNVIFNDGGAATVVNTVSVGLMGPIGGALAILGVVACPITSGDT
                     AFRSARLTIADAMNYNQDAVKNRFLIALPLFAVGVALTFIDFNIIWRYFSWANQTLAM
                     IMLWTGSAYLVKANKNHYITTLPALFMTVVTFSYIMQAKEGFRLPVNISNGIGVIVAI
                     ILGLLFFKKAKHIKEQNNHKLAS"
     gene            complement(45243..46013)
                     /locus_tag="PC512_001466"
     CDS             complement(45243..46013)
                     /locus_tag="PC512_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2441222.1"
                     /translation="MRAIIVEDEFPARKELRYFIENKSGIEVVSEFTNGIEVLDFIQE
                     NKIDVIFLDINIPHLDGMLLAKTLNQFKSRPKIVFITAYESYAVDAFSLDVFDYILKP
                     YSEERIISMLNKLEKSEMSDIELFNVNSNLYKYKKEAVNQEIEEITHKISLWKGDKLV
                     VIDIDDIYYCEANERQTFIYTEKEKFILKEGISEVENLINDKTFFRTHRSYIVNLTKV
                     KEIIPWFNNTYILKLKNSDYEVTVSRSKVKEFRLLMHI"
     gene            complement(46018..47220)
                     /locus_tag="PC512_001467"
     CDS             complement(46018..47220)
                     /locus_tag="PC512_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HDF2441223.1"
                     /translation="MKTSILIALIEKTSLIVVLFLLITKLKIFKQIFQKEEYSFNDLV
                     CIALVFTFLAIFGTYSGINYMGSIVNTRIISIVSGGILFGPMVGITAGVFSGIHRYFM
                     DIGGITSVPCLLSSILAGVLSGFLYKRIPKQHRVMYGILVGMISESFTILLIYLISYP
                     HSLAIQIIGGIYLPLIVGQIGIGFVISIVEGIEKDKKDIEARNKAEIKALQRQINPHF
                     LFNSLNTIASFIRFSPDKARELIINLSTYLRYNLEYSDNLIDINKEIEQVKSFVEIEK
                     ARFGELLTVSYDIEDVNIKIPSLIIQPLVENAIIHGILESGRAGVVKISIKKLPYSLE
                     NTVRISIEDNGIGISEEIINNVYQDNMPENKIGLYNVHLRLKLMYGRGLNIRRIDNGT
                     LIVFYVKE"
BASE COUNT        15928 a         8174 c         5160 g        18490 t
ORIGIN      
        1 agaaattctt caatatgtgt aaggcaaata tatatttcta ttgcaaattt ttgttattta
       61 tgataatata aatatgtttt tagtctttaa atagttatca ttttaaggag gtgtgcgtag
      121 atggcaaaag tatgtagcgt atgtggtaaa ggtaaggttt ctggaaacca agtatcacac
      181 tcaaataaac ataataaaag aacatggtca gctaacttaa gaagcgtaag agcgattata
      241 gatggagctc ctaagagagt aaaagtttgt actagatgtt tacgttctgg taaaattgaa
      301 agagcttagt aaccacgttt aaaagcctac ttccgtaagt aggcttttta atttaatcat
      361 ttttactctt tctcataaat tttaggatta tacttgaaat ccattttggt aattttattg
      421 ttactacttt catcaatact caccccacac tttatagtta aaactatttt aacaaaaaaa
      481 taataatgct ccacatccaa taagtattaa tgcggtaagt gctgaccaaa tccagccagg
      541 aagcaacatt gacagaatta cagccattcc tgttgctaga caaagtattc ctagcaatac
      601 cttagacttg ttatttctca tggaacacct ccacatagaa cctgtatcta taaatatttt
      661 catattcaag tttatgcgac agttttccat tttagaccaa taaacacatt atgtaatttt
      721 aatttttcat actagaatta ttactgaact ccgatataga ttctacaata tccaaaattc
      781 ctttttttct acttaacctt tcaggtccac tatataaaac aactggtata actttaggaa
      841 gtttaaaatt tttatcttct atttcttcaa ggcttttttt cataataaaa cttttccaaa
      901 tttgttctct atacgatttc aatcttggga caatttcagt atccatttct gtttgaaatt
      961 ctaacactat ataatgtgat actttgccac ttttagaaaa taccttataa attatatcaa
     1021 cttcttttcc tttatattca catataaaag atgtttctaa ctctatattt ttaagagtta
     1081 attcttttgc tattgagaca cttgtaaaat tttgaatcaa acttaaaaaa ctttctttat
     1141 ctgaatacat tcttctgtac tcttctcgtt tttcattgct tctttttaaa ttcatacagt
     1201 tcctcctaga ctatagaccc tctatttttt agtaaagata gtctataaat tttatttttt
     1261 aattttcatt agtgagtatt gacagttgtg tgtaaaatat ccagtaaaga tattttttta
     1321 tatttttatt aaaagatata aatttttata ttttaatgta ttgacattta cgttgcgtaa
     1381 aagtgtatat ttaatttata ggaggtacta cttatggaat atacagttca aaaattaagt
     1441 aaactagctg gtataagtac tagaacactt agatattatg atgaaatagg tcttcttaaa
     1501 ccacttaaaa taaattcttc aggttatcgt atatatggtc aaaatgaagt taataaactt
     1561 caacaaatac ttttttatag agaattagga attaacttag aaaatataaa aaacattata
     1621 aattcaccaa acttcgatag tttaagtgcg ttaaaagaac accataataa attactagcc
     1681 aaaagaaagc aaattgattt actaatagaa aatgtaacta aaactatagc tctgaaggag
     1741 ggaaaataca ctatgacaga tatagaaaaa tttgaaggtt ttaaagaaaa gatgattgat
     1801 gaaaatgaaa aaaattatgg aactgaaatt agagagaaat atggtaaaga tattatagat
     1861 acatcaaata aaaaacttaa aaatatgtct aagcaagatt atgaaaattg gcaaaaccta
     1921 aatatcgaaa taattagtaa acttaaaaaa gcttttaaaa ctggtgatgc ctctagtgaa
     1981 ctggctcagg aagttgcaaa attacatcat aaatggttga gttacacttg gaacacatac
     2041 tctaaagaag ctcattcctc tctagcacag atgtatgtat atgatgaacg ttttacatca
     2101 tattatgata gagaacaacc tggattagct aagtttttaa gggatgctat agtaatatat
     2161 acaagagata aataatataa aataataaag gtggtgtctc aaaatgaact ttttagttca
     2221 tgagacactc ttttttgtat gaaatcagat atatttttat cattttatca atgaaaaaca
     2281 ggtttctctc tctattttga gacagaatct ttattgtata ataattataa tcaatacaaa
     2341 ataataacaa attatacaaa acttacttat actatttatg ctaaaaacaa aaaatatttt
     2401 attaaagttt ttaaaactta tgtaatataa aaatctatac tatagacttg attatggaaa
     2461 gaaaattatc aaaatcatta caattagata tactatctct aatatcattg tcatgaatta
     2521 tctttaaaag gatatcataa atggagttta tttttatata atcatcttta tttatagcca
     2581 acatcatgat taatttaaca gtagaatctt cactccaata tattggttca tccaatatgg
     2641 aaatacaaat cttagttctt atagagctta attccatagg atgaggtata gctaaaaaat
     2701 catctatatt ggtagaagat aaactttctc tgtaaaatac agattcagca aatgatggaa
     2761 atacaatttc actttgagtt aatttgttgc acatcaactt tataagctca tctttatctt
     2821 tgattttagg attaacaata aataaatttt tatcaaagaa attgtccaaa agattactat
     2881 aaatatggga attattagtg attgacttag atatattctc tatatctttt tttaatagtt
     2941 ttaaatccac taatacaata ggaatactat catgatttaa aggaattgtc gatattatta
     3001 tatctacatc tgacaattca ctagctaaaa attgattaaa tgatagacat tgaagtatat
     3061 ttattttatc atgaaaaact ttgtttaatt gaacctctaa taacctactt gaaccatacc
     3121 ctgaaccaca tactaatact acgtttttac acttaatatt actttgaaaa aatctctcta
     3181 ttccagcacc tatatgcagg gatacatatc caatttcatc ttctgttaaa gagtaaatac
     3241 tatttttaaa aactttttct atagcattta aagttatttc aaatgctaaa ggataattac
     3301 tctttattgt atttataagg ggattcacct tatttaaatt ataagattta gaattgagaa
     3361 ttgatttaaa gtgcagtact aaatcatcaa ataatacact atcatttcta aggtcaaaag
     3421 tatattgatt gttgattact tctaaaattt cttcaacata ctctataatt ttagtatcta
     3481 ccctattgga aacgttatcc aaaagagaac ttttagttat aaaatgatta tatagataaa
     3541 ctctgtctgc ctttgaaata attatagtat atttactctc aatataatta aatatatttt
     3601 caacagttgt attcgattga aaatctgtta aaacaacatc taaaacatta tctaagcagt
     3661 aaccatcaag tattctactt acagtaatag ctaaatggat aataaagttt tttagattaa
     3721 aatctaggaa attgatatta aatttattaa tttcacttaa cactaccctt tgaagctcta
     3781 ttaaatctac attattaaat aattctattt ctctatctgt aattccaatt atatagtttt
     3841 caaaattcct atttatcata ttattagaaa tacatcttcg aatatctatt tccttacctt
     3901 caactttaac tccataatat ggcttagaaa ctaatattaa attatacttt gacaaaatag
     3961 gctttattct ttttatgtca tttagtattg taaatttact cacatacaag ctattagcta
     4021 aatcttctag ttttatatat gtattgttat agagaatata ttttaaaata tattgatttc
     4081 tttctatagg agaatctggt atttcacttg aatccataat atcatcagat attaatgcta
     4141 gatactgttg gtataatgct aaattaagaa tatctatata atatccttct ccttttttta
     4201 ttttaataat agcaccattt ttctctaaag ttccatttat agaagtaata tcatttctta
     4261 tagttctctc actcactttt aaatgattac ttaaagtttt acaagtaatt ttatcatcac
     4321 tttcatttaa taatttaaac aacgtgagca atctcttgtg cataaatatc cccccttata
     4381 gaatttcttc taaattatac tatttacact catataatac aattactcta ataaaattgt
     4441 attataataa tttatttcca cttctatatg gaaattagtt attatcataa tataaatttc
     4501 catgtcgaag tggaaattag ttatatttaa tttaattagg ataatgatta caatataaat
     4561 ataagttaag acattatgaa tggagtggaa aaatatatgg tactacaaga aaaatatata
     4621 tttatagata aagacttaaa aagcaaagaa gaagtattaa attttattgc agatagtgct
     4681 tatatactag gtattacaac taataaagag gctcttttaa aagaccttct aaaaagagaa
     4741 aatgaatttc caacaggaat aaaagatgga tttgcgatac ctcatacaaa aagtgtaaat
     4801 gtaaaggaag cttccatact ctatattaaa acaactaacg agttagagtg gaaaacttta
     4861 gatgatagta aggttagata tgtatttagt ttgttagccc cacataaaaa tgaaggaaat
     4921 atacatttga aaactctatc taaattagcc acatgtttaa tggaggatga ttttacaaat
     4981 gaagttaaaa atgctagtga tgcaagtcat ttagtaaaat atataactaa taaaatgaag
     5041 gaggaataat tatgaaaata gtagcaataa catcatgtat agcaggatta gcacacacac
     5101 ctatggcagc aaaagcttta gaacaagctg catcaaaaat gggtcatgaa atcaaagtag
     5161 aacaacaagg tgctatggga cgagtaaata ctataacaaa agaagaagca caagatgcgg
     5221 actttatact tatagcatct gaccaaacta tatctggaat ggaaagattt gatggtaaaa
     5281 aggtgataaa agtcaaaata ggtatagcgt taaaaaaacc agaagctgtc ttaacaaagt
     5341 gtatagaagc tatttcttaa taaaaaaatc tcactctaat atagaatgag aaaaatcaaa
     5401 aattaaaaaa ttgtctaatg taattataac atattatcaa aaaatataac aaacttatat
     5461 aggaggatta aaaatgagta aaaaaaataa atctctttta agtgaactta agggacactt
     5521 aatgacaggt atctcatata tgttgccact tgtaataggc tcatctttag ttgtagctat
     5581 cccaaagctt acagctttag caatgggtat aacaagttta gatgcttata aaaatgtatc
     5641 tggtttttat catattcttt acttaatgga acaagttggt tggactggca taggtctatt
     5701 aaatacggta ttagcaggat ttatagcatt ttcaataggt gagaaaccag ctatgggtgc
     5761 aggttttatt ggtgggctca tagcaagtaa tactaatgca ggattcttag gagcagtaat
     5821 agcaggtttc tttgctgggt atgtttgtaa gtttttaaag aaaaaaatta aaatatctgg
     5881 gtcagcatca ggaatgatgc cacttataat aatgccactt ataacagttg gattaactgg
     5941 ttttttaatg agtgttgtat tagcaggacc tttaggaaac ataaatactt cattaaatgc
     6001 ttgggtagct gaaatgtgtc aaaatggaac aaattcggtg gtattggctt taattttagg
     6061 cgcaatgata ggattcgatt taggtggacc agtaaataaa gcagcttgga tggcaggaaa
     6121 tgcattattg ttagagggaa tctatctacc agcgatattg gtaaactgcg caatagttat
     6181 acctccacta ggatatggtt tagctacatt cataagaaaa tcaaagtttt ccaatgcatt
     6241 agctgaaaca ggaaaaggca atatagttat gggtataatt ggaataacag aaggtgcaat
     6301 tcctttcact ttaacaaatc cattaaaatt agttcctgtt aatatgatag gatgcgcttt
     6361 gggtgtagga ttatcagctt tgttaggtgt acatgctata atgcctccag ttggtggatt
     6421 atatggattt atatcaatag gttctggatg ggcttactta gtaggtgcaa tatttggagc
     6481 tttagtaata gcaatattat caacaacttt agtagacttc aatgaagatg aaactacgga
     6541 aaatacagaa tttgatgaaa tagagttaga tataatgtaa attaaaaact taattttaga
     6601 taattgagaa ttgagtgtac tctcaattct caattaaatt ttgggaggat ttttatgaaa
     6661 aagacaaaag tacatgtagt tccacacagt cattgggata gagaatggta ttttacaaca
     6721 tcaaggtcaa aaatatattt aatgaaagat tttcaagata tattagacat attggaagaa
     6781 aaagaagact ttaaatactt tactatggat gcacaagctt ctctcttaga tgattattta
     6841 aaatggagac ctcaggatga atatagaata agagatttag ttcaaagaag aagattagtt
     6901 attggacctt ggtatactca aacagaccaa ttggttatat caggagaatc tataattaga
     6961 aacctttact atggaataga tagatgcaat gaatttggtg aacctatgag ggttggatat
     7021 gtaccagatt cttttgggca atcagctcaa atgccacaaa tatacagagg ttttggaata
     7081 gatagttcat tattttggcg tggagtttct gatgatatgg tagatacaac agagtttata
     7141 tggaaaggtt ctgatggttc aaaagtatta gcagttcaaa taccatttgg ttattactat
     7201 ggaggtaata taccagaaga tgattctgat ttaaaagaat atttaaaaga tataatcgga
     7261 aaacttaagg ttaaagcttc tactaataac gtatattttc caaatggatt tgaccaagca
     7321 ccaataagaa aaaaccttcc tgatatatta aaaaaagcta atgaaataga taatgaaaat
     7381 gaatacgaaa taagtgatat agaaaactat atagattcag taagaaatga aagaaatgaa
     7441 tttacagagc ttaaaggtga atttttaaat gctaaacata tgagaataca caaatccata
     7501 ttctcctcaa ggtcagacct taaaataatg aataacaaat tagaaaatta tattacaaat
     7561 gtacttgaac cattattaac attaagttat tcacttggaa atgaataccc tcacctagtt
     7621 ataaaagata tatggaaact tatgtttgaa aatgcagctc atgacagcat aggttcttgt
     7681 aatagtgaca caacaaatga ggatgtatac acaagataca aacaagccag agatttgagt
     7741 ataaatttat tagatttgca tatgagactt ataagtactc aaatcaaaaa taataatgaa
     7801 gaaataacat taacagtatt caatggattc ccagaagtca gaaatgaagt tgtagaattt
     7861 gatacttata ttccaggtca agattttgtg ataaagaata aaaatggaaa aattcttaat
     7921 tatataataa aagaaaaaga agatattaca aattatatat taactcaaac aataagatta
     7981 aacccaagta aaaaaatata tatacccaaa actgtatata gagcaaaaat tgcactttca
     8041 gtaaaagata taccaccaat gggatatact caactagttt ttgaattgga tactaaaaat
     8101 aaatgtgaaa tagaaacaag taattgcaag gaaatagaaa acaaatacta caaaataaca
     8161 gccaataaaa atggttcatt agaaatatta gataaagaat ctaataagac ttataaaaac
     8221 caagctgtaa ttgaagacaa tggagatgat ggagattcat acaactattc tcctccaaga
     8281 aaagatattt atgtttcatc tttagattct gtatcttcag tagaagtgct aaaatcaaac
     8341 attcaagaag aaatgatact taaatattca ttgaccatac caacttcact ggaagaaagg
     8401 gctataggta aagtttctgt gaaaatgcca gtaacaatga aaatcacctt agaacctaaa
     8461 gaacaaataa ttaagtttaa tgttaatata aaaaataacc aagcactatc tcatagagta
     8521 agagttttat ttaatacaga aatagcatct aagttttcta tagcagatca acaatttgga
     8581 ataatacaaa gaccaacagt attagaaaaa gaccttgcat tgtggaaaag agacaattac
     8641 tcatggcaag aaaaacctat aactatcgaa ccaatgcaaa gttttgttac tttagaggat
     8701 ggacaaagag gaatagcatt aataactggt tgtgtaagag aatatcaaat agttggtgat
     8761 aatttagata caatagcatt aacactattc aggtcatttg gatatatggg aagagaaaat
     8821 ttactttata gaccaggaag agcttctgga gaaaaaataa tagcaacacc agatgcacaa
     8881 ttacttaaag agttaaactt tgactttggt ctttacatat ataacaataa atttgatgaa
     8941 gcaaatgtag ctaatacagc taagagattc ttaacaccta tacaaatata tgaatatgct
     9001 gattttttaa atggtagact tatatttgca ttcaatgacg aaaaacaaat atatgaaaat
     9061 gaatttagtt tgatgaatgt aaataattca aatttcacag taagtgcaat aaagaaagaa
     9121 gaaaaaggag atggaattgt agttagaatc ttcaatggta tgaaaaatga ggatgctaag
     9181 ggaagtctta acatcaataa aaatgtcaat gatgcttata gtgcaatgct cgacgaaatc
     9241 tatgataata ctagcaagct taaagtaaat actaaaactg tagaggtaaa ttctttatca
     9301 cattgtaaag tacaaacaat agtaattaaa taatataaaa tagcttatac aagatttcaa
     9361 aataaattgc tagtactatg ttaatagtaa agccagatat tatgctattt ataagctctg
     9421 taacactaaa taacattttg taaaataaaa aggtgaacct tgtatattag gattcacctt
     9481 ttttaaataa atcaacattc tgttttaaaa taacatttat aagctgtttt gaaataatgc
     9541 ttacaaatta ttttaaaaca atacctataa atttttattt aaagaataca cataaatatt
     9601 tccagattct tttattctat agactttata attattaaag aagtctaatc taatttttgt
     9661 taaaagtaat tgtaactttg aataaatcac catccacact tatattcatc ttaccaccct
     9721 gtaattctat aaaacttttt gctatcgcta aaccaagacc agaaccttct gtgttacgtg
     9781 atttatctcc tcttacaaat ctctccatta tatcatctac actaaaatca atctcagatg
     9841 cagacatatt tttaagcata atatttactt tattatctgt ttctaaaata tcaatataca
     9901 ctcttgaatt tggcattgca tatttgctta tatttattat aagattttca aatactctaa
     9961 atgtacgctg actatctaat ggtaatatta ttttttcatt agaaaagtta ttctttacta
    10021 ttagagatga atctgcaagt ttgtcatcta attctaaaag tgtctgcttc attagagata
    10081 caatatccac atttactata ttcaaataaa catctccact atttgccttg cttacttcaa
    10141 acaaatcttc tattagatgt tgcaatcttt gtgactttct gtctaatgta tcaatataca
    10201 acttacgatt ttcatctgtt atactttcat cttttaataa atctatataa gtgattatag
    10261 atgttagagg tgtttttaag tcatgtgata catttgatat aagctctgtt ttcatctttt
    10321 gactcttaac ctcttcgtca acagcttttt taaatccagt ttgaatattt cctaattcat
    10381 cttttatagg attaaaaaat cctaaatctt tttccatatt tacatctaag tttccatctg
    10441 aaattttctt tgtaacatct aaaagttgat tatattcata tattgtcttt ttagagtaat
    10501 ctgacagtat cttaaataat actactgaat atattaatgc gagtattatt ccaaagaacc
    10561 acatactaca cattataact ataatcaata aatttattcc caaaattgta actatagttt
    10621 tatttggctt ttctttcaga tttattgttc taatttgatt aataactgct tttcctgctt
    10681 tttttaacca tacaaaaaac attcctgtca cagtatgttt tgtaaaatac tctcttattc
    10741 caacatttaa aatgtgtttt aaaagtatta taaatacaaa tattattgag aatattacaa
    10801 accaataagt taaattcatt aaacttacca atatactagc cattttagca cttatgtcat
    10861 tgtttataag gtactctaca taattcccac tcaaggtatt acttattata acagtaggat
    10921 ataaatctac aagcccctgt ataatagcaa gagcaataaa gagtatctct aacggtattc
    10981 ttgataatgt atcaaatcct agcaactctt tagattttct atatgggaat gctaaagcta
    11041 caataacaac tatagctaat ataattttta aaatcattcc agaaatctta taataagaat
    11101 tattttctac attgcttata tatgaaatta taccatcatc aaaataagta tttccataac
    11161 catactctac actatcacct ttacttatta ctttaggtac agcatatact aatgttatat
    11221 tttttattgg agataactta tatgaaattg aatttcctcc taaacttgta tccattaaat
    11281 cttctcttgc tttagataac aacatttgat taataatttt ttgatttact ccataagaat
    11341 ccacaatatt tacttttcca tctttatcaa aattcattac aacgtagaat ctatagtttt
    11401 cttttatatc tgtaatctgc ttttgtcttt cctcatcatt catttctgta ttttttgact
    11461 gattttcatt agaattttct tttgaagcat cattttttgt tgtatcaagt actcctaatt
    11521 ctttattatc attaaaaaat tcaaaattgc tttctttatc aactaaatag tactttaaat
    11581 tctttcctga cgctttaatg aaatgctccc aattttcaaa gttttcatta aaatctgcat
    11641 taatactatc atctgtataa taagtttctg aaccatcata agtatctttt tctttactta
    11701 cattttttat atagttcata gtttcttcat tgataaatag ctttgatggt tgtatcatct
    11761 taccttcttg ttcttccttc atattatgat ataaaacata acttccttta tatatactat
    11821 ctacaaagct ttcctgttca aatggattct ctgctccacc tttagcactt gcttgtatag
    11881 tagaatattg actaatcata cctaatgatg ctgataacat aagtataaaa actataatag
    11941 taactatata tttatcttta aattttttca attttgtatc caacacccca caccaccttt
    12001 aaatatttag gattttttgg gtcaatttct atcttttccc ttatattcct cacatgtacc
    12061 ataactgtat ctgtatttac agcattctca ttccaaactc tttcatatat ttcatcagca
    12121 gaaaaaactc ttcctgcatt tctcataagt aaacttagta ttttaaattc tataggagtt
    12181 gtttttatat actttccatc aatactaact tcttttgtat tttcatttaa ttctaatccg
    12241 cctattgcaa acacactatc gtcactttct accttttgct ctttatttcc aaccatgttt
    12301 agatacttag tgtaccttct aagttgtgaa ttaactctag ccaatagttc taatggctta
    12361 aaaggttttg ttacataatc gtctgctcct atattaagcc ccattatttt gtcaacttct
    12421 tctgattttg cagatagcat tattactgga aaattatagt tttctctaag cttcattgta
    12481 agtgttatac catccatttt aggcatcatt atatcaacta tagctaaatg tatttcttgg
    12541 ttttctataa ccttaagacc ttctaatcca ttgtatccct taaaaacatt atatccttga
    12601 tttaatagat atatttctat agcatctgct atctcctttt catcttctac caccaaaata
    12661 ttatatgaat tcattctaat ctcctttata ttaatttata aattttcttt acatatatga
    12721 ttatacaata tgatagaagt ttttccattt atatatatat ttatatcttt tgttctggtt
    12781 atttgtattt aatgtccatc ttagaaacct ccttctagtt taaatttaat attttttcat
    12841 tttgttttat atacttaata ttaaaattaa aaacttaaga tattacatat acttttctaa
    12901 agattttcta aagatttaaa tatatttaaa attaatatac aaaaaaaagt agttcttatt
    12961 gtattaatta aattaatgat ttgaaatata aaattaatat caataaaacc tactttttaa
    13021 ttttttaaat atttattttt aatttatttt gtttttaatt tacttcgatt ttaaaatgtc
    13081 cttgactttt attttataaa tgtacatatt tcttctactg gttttttaga tggactcttc
    13141 aaattgtcct ctggcactcc aagagctaac attgcaccta aaaaatactc tcccttttca
    13201 aaaccagttt ctgcttctaa aacagcttct atctcatctg ctgcatagtt ttgacttgtc
    13261 aaccaacaag aaccatatcc aagttcaatt gctgatagtg taaagttttc aattgcagca
    13321 cctagactct gcatacctgg atttcttata aataatttat ctatagtctc cttaggtgca
    13381 tctataagct ctaattcata atatcctgat ggattatata cctttgtaaa aactaatact
    13441 aaaactggag cttttaagta aaatagtgta aaatttttaa caaattttct aaatctatta
    13501 gccttatcca ctgatacttt atccatttct acaagtattt cttgttgctt tttagttatc
    13561 acatctgcta tcttttccat taaatcacgg cgttttataa caacaaaatg ccagttttga
    13621 atattcttgc ctgatggtgc tgcacctgct gcttttatca tttttaaaat atcttcatct
    13681 gatacatctt gatttttaaa ctttcttaca ctttgtcttt taaaaatagt atcttgtaat
    13741 tccattttta aatcccccca taactttttt attattttaa tataattttt aaactcatct
    13801 tattttaata tatcatgttc taacaaatct ttaaatgaat ctataaaata atcatataca
    13861 tctacattcc caaacccata tttggcatat ataaaaggta tacctacaaa cttagcacta
    13921 tttgcatcac cttgcgtatc accaacatag attggattta ttaatttatt tctttcaatt
    13981 ataagtttat tattttctcc tttatgcaaa ccagtattac caggacattc aaaatctata
    14041 aaatactgtt ctagtttatg tgcttttaaa aaagattcta tatatccagc ttgacaatta
    14101 cttactataa ataatttata ttttttagat agtaatttaa gagtatcttc tatatcatca
    14161 aataatttag ctccattttc agataaatag tcacattctt tcaaagaaca ttcattcaat
    14221 aaattcattc tttcttcttc acttaaattt ggaaataaac gatttgctat ttcctcaaaa
    14281 gaaagcccca taagacttct aaataaatct tttgtgacac ttaattctat ttccttatgc
    14341 tcacttaaaa catcctgcca gactttgcat acttcttcag ttgaatccca caatgttcca
    14401 tctaaatcaa aaataatact atctaccaca aaaaatcccc cttatgtcaa agtttattat
    14461 atatttataa ttatatacta aaaagcagat acaatcataa atatatttta cttgattgta
    14521 tctgctctac aatataaaac caattgtcaa aatcaaattt tataaatttc taactacaag
    14581 tacacagcct tgctctactt taatcttaca agaattactc aacataacat ttgatattcc
    14641 aataggtaca gagtatttca tataataatt atcgagaggg tattctaagc cagtaagtgt
    14701 tacaccctta gcatcaccat ttatagctat tacagaaata gtgtcccctg ggtttccata
    14761 caatgaaatt tcctcatttt caactatata catctcttct ttatcagaaa gtatcctaga
    14821 atatatacca tcttctttta aataatataa tagctttata tttgcaagag tgtggtcaat
    14881 ccttccccct aaagcaccaa aaaaatcaat atgatttgct ttaagtgtct tagctaaaaa
    14941 aagacaaagc tctgtatcag tctcatcttt tttagatgga aatttttcaa atttaacacc
    15001 tttattttta tagaagttta tcttttcttc ttctactgaa tctaaatctc ctaatatata
    15061 atctggcatt atttccattt tataagtgtg atttgcccct ccatctgcac atattatgca
    15121 gtcataacat tccttaatta taatatctct tgtaacttcg taatcttcaa tttcgccatt
    15181 taaaacaata cagattttca ttattaaatt taaactaatt cttcaagaga agcattcttt
    15241 ctaaataaat taactgtttc ttgaatgtca tcacttccaa atattgcaga acctgctact
    15301 attacattag ctcctgcttg tacaacttcg gctacgtttt tagggcttat accaccatca
    15361 acttctatat caatgtttaa tccttgacta tctataatag cttttaactc tttaatctta
    15421 tctaaaacac aaggaataaa tgattgtcct ccaaatccag ggttaacaga cattaataat
    15481 accatatcta aatcagatag tacatgttta atcgtatcta ctggtgtagc tggattaagt
    15541 actacaccag cttttattcc atgtgatttt atattttgta tagttctatg tagatgaaca
    15601 caagcctcct ggtgaacagt tattatatca catcctgctt ttacaaattc ttcaatatac
    15661 tggtctggat tttctatcat aagatgagca tcaaatacca tatttatatt ttctttcttt
    15721 aaacttttga ctacaagtgg tcctaatgta atgtttggta caaagtgtcc atccattaca
    15781 tcgatatgaa gatattcaca tcctgcactt tctacttttc ttacatcttc taataatttt
    15841 gcaaaatctg ctgataatat tgatggtgct aatttaatca tgtttctaat acctcctact
    15901 attattttgt cttatttcat gtagcagctg tatataacta tcatatcttt ctttagatat
    15961 ttctccattt gtaacagctt cttttatagc acaattaggt tcattttcat gaatacactt
    16021 tgaaccaaac ttacaatcat taaatttatc aaattctata aaataatctt taagttcaac
    16081 ttcctctata tcttcaagtg caagggaact aaaacctggt gtatctgcaa ccattccacc
    16141 aaattctaat tttaaaagtt cagcgtgacg agtagtatgt tttccccttt ttattttatc
    16201 acttacaact cctgtttgaa gtttaaaatt ttcatctatt tcatttaata agcttgattt
    16261 tccaactcca gatggtcctg caaacactac tacattttct tttaattctt cttttacttt
    16321 atctatattt aacttagtaa tattgcttac aggaatgact ttataaccac taagttcata
    16381 tatattttta acagtttcta atgtatcatt atcatctaaa tctgcttttg taaggattat
    16441 tacagtttct aaattttctt tttctgccaa aactataaat ctatctaaaa gagataagtt
    16501 tggtttagga ttttttattg cgaatactat taatgcttta tctacatttg caataggagg
    16561 tcttataagt tctgtatctc tactgtcgat ttcttctaag ataccctttt tttcatcttc
    16621 atcaacaatg cttattttga ctctatcacc aaccaaaggt gttattttct gctttctaaa
    16681 tatccctcta gccttacatt cataaatacc attataagta tctacataat aaaatccact
    16741 aatccccttt ataatttttc cttctagcat caaatgcctc cctttataaa atttatataa
    16801 acacatactg tttatgagta gtatatcgtg ttattctttc ctatttttat ataataccac
    16861 atttttttta aataacaaat cctccgtttg gactaattac ctgaccagtg ataaaatttg
    16921 atttgtctga tgccaagaaa atagcacaat ttgctatatc ttctggagtt cctagcctca
    16981 ttagaggggt ttcttccaca agagcgtcta tatcttcctc attatatcca gataacatgt
    17041 cagtattaat gacacctgga gctatgctat ttactctaat atttgatggt cctacttctt
    17101 tagctaatgc ctttgtcata cctattatac ctgcttttgt tatagaataa tgcacttcac
    17161 aagacgcacc tgatataccc cagattgaag atatattaat tatatttcct tttttttctg
    17221 atatcatgta ttttaaagca acttgtgaac aataaaagct tccttttaaa ttaatattca
    17281 tcatattatc ccaatcttca tcagttatat ctgtaaacaa cttatcttga cttacaccag
    17341 cattgtttac aagtacatcc aatcctccaa attcttttat acaataatct accatatcct
    17401 ctacatcttc tctatttgaa atattagcct taaaaagttt tacagaaaaa tttttttcat
    17461 ttaatatagt gtacaactct ttagcttcat tttctgactt attaaaattt actaatacat
    17521 tgtaaccttc ttttgcaaaa gctttagaca tagctttacc aatccctcta gctcctcctg
    17581 taattaaaac tgttttcttc ttcataaata cttttctcct tatattataa ccaattcagt
    17641 attttataca aaacaaactg ccctttaaag aaaatatttt ctataaaagg acagctctta
    17701 ttttattaat atttattctg ttttaccaat gtttgcgcca gttcctgatg aagttcctcc
    17761 attatctcct gagtttgagc ctcctgaact atctccattg tctcctgagt ttgaacctcc
    17821 tgaacttcct ccattgtctc ctgagtttga gcctcctgaa cttcctccat tatctcctga
    17881 gtttgagcct cctgagtttc caccactatt tcctgagttt gaacctcctg agttacttcc
    17941 attattgcct gagtttccac cactatttcc tgaatttgag cctcctgaat ttccaccact
    18001 gtttcctgag tttgaaccag gttctgttgg tgtattattc tctggtgttg ttggtttttt
    18061 atctggtact gttggagtct gtgtatttga tttttctgaa cctttgctta catatagatt
    18121 tacctcatca ccttcctgag ctcttgatga gccagcacct ggactctgac ttaaaactgt
    18181 accttcttta tatattgagc tgtattcata cttaacagtt cccactttta agttattttc
    18241 ttcaataagt tgttttgcat tactcaaagt aagtcccact acattaggaa cagatgcctg
    18301 acttgaacct ttacttacga caacatttat agtatcaccc tttttgacat ttgtacttcc
    18361 accttcaggt gtctgtgata ttatacaatt ttcatcaact tcactattat actcttcact
    18421 ttttacactc aggtataatc cttctttttc aacagcactt tgagcttctt ctaatgtcat
    18481 atttacaaga ttaggaacag tcaaagattt attgccaaac cctccagcaa ataaaaactt
    18541 atatgctaag aatacttgag cacacaatat cagtatcaaa acagccgcaa ttacttttaa
    18601 tcttcttcta gattttgggc tttcctgttt tttcttcttt ttcttagttc tcttacttgg
    18661 agtactctta ggtctctgat tctttttagc tctcattatc tcttcctctt cttcatcttc
    18721 atcatcatct tcttcataaa aatcatcata gtaatcttca tcatcatcca aatcagctac
    18781 ttcaacaggc ttaaccactt tttcaggagc tggttttgca agtgttggat ttacaacttt
    18841 attaatttct ttttcatcaa ttttcttagt tgcaaaatca tcatattctt ttataaaatc
    18901 taaatcaata tttttttcta tatactctat atcttctatc aattcttcag cagtttgata
    18961 tctatctgca ctagattttt ctgtaagctt ttttattgta gttcttacac tttgaggaat
    19021 cctaactttt tcttctgatg taaagtctat atcatcatta atgtgttgaa gtgctataga
    19081 aattggacta tctcccctaa atggaacttt tcctatcaac atttcatata aaactatacc
    19141 tagagaatac aggtcagcat tattagttac aaatttacct ttagcttgct ctggtgaaaa
    19201 ataatgcact gaacctatta tactaccaat attagtcatt gttgaatttg aaacagcttt
    19261 ggctatacca aaatcagcca cttttactac tcttccttca tttgatatga gaatattatg
    19321 aggttttata tctctatgta taatcccctt tttgtgcgct gcactaagtg ccatagctat
    19381 ttgttttgtt atatctaatg cagtatattc atctaatata ccttcatctt gtataatctc
    19441 ttttagattc ttcccatcta caaactccat tacaatgtag tgaacttttc catcttcacc
    19501 aacatcataa acatttacta tatttggatg tgaaagactt gctactgctt ctgcctctct
    19561 tttaaacttt gttagaaatt catcatcatc tacaaattca ggtctaagta ctttaagtgc
    19621 aacagtcctg tttaataatc tgtctttagc ctcatataca aatgccattc ctccatcacc
    19681 aatcttcctg atgatttcat atcgatttcc taaaattgta tctcccacaa tatcaccgtc
    19741 ctaattatac ttttatcact ataaccgaaa cattatcttt accagaaaca tcattggcca
    19801 tacttatcaa ttcttcactt atattactag ttctctcata ttcataatct aatattaaat
    19861 ctcttatatc ttcatcatca ataaacccag ttaatccatc tgtcgcaaga agtattatat
    19921 cacttttttt gatttctttc ttaaaaatat ctacaacaac catatcatct gttccaattg
    19981 ctctagttat tctattcctc tgtggatgtc ttcttgcctc ttcttctgta atgacatggg
    20041 ccatcataag ttcttcaacc acggaatggt ctatagttat tttatcaaat ttttcatctg
    20101 ttaacaaata acatctgcta tctccaacat ttgccacata taagacatta ttatacacta
    20161 tagccgtaac taatgtagtt cccattcctt caaattctat atcttccata gattttttgt
    20221 gcacaattga gtttacatta ttataagcct gttttaatat atcatctata tagtctattt
    20281 ttacattatc atgttgtaat aagttttcct ttagaaaatc aattatattt tctactgcta
    20341 atttactggc gacttcacct tttttatgtc cacccattcc atcagctatg gcaaatattc
    20401 ctattggacc atgttctgta tctataactt ctccctcaca atagtcttca ttgttttttc
    20461 ttatttttcc tatatgggag gcacaactat aaaccatacg acttcctcct tacaaattac
    20521 ttgtattttc ttctcaattg cccacaagct ccactaatat cagaacccat agacatccta
    20581 actgtggcag gtatattgtt cttctccaaa ctatccctaa atttataaat aaatgcttta
    20641 tctggctttt catattctct ttcttcaact ttatttattg gaattaaatt tacatgacat
    20701 agcatacctt ttaggagctt agctaatgcc tttgcttctt tttctgagtc atttacccct
    20761 tttataagag aatattcaaa tgtaaccctt ctatttgtct tttttatata atatctacat
    20821 gcattcaata tttcttcaat agaataagca tttgctacag gcataatttt tcttcgttct
    20881 tcatcatatg gtgaatgaag tgataaagct aaatttatag ctatttctaa gtctgccaac
    20941 tcatacattt taggtactat tccacaagtt gaaagagtta tatgcctata ccctatatta
    21001 agaccatttt tttcgttaat tatttttaaa aattgttttg tattttcaaa gttatcaagt
    21061 ggctcaccac tccccatcaa tacaagattt gataccctct taccagtatc ttcttgaatt
    21121 ttaataactt ggtctaaaat ttcccatggc tctaagtttc taattaatcc atccattgta
    21181 gatgcacaaa aattacatcc catcctacaa cctacttggt tagaaacaca gacagtaact
    21241 ctactatcat aatccatcat cacagtttct attatatttc catcatctaa taaaaacaaa
    21301 tatttttttg tattatctac cttagattct aactttaatt ctatatctat atgccctata
    21361 catgaaacct cttctaattt atttctcaaa ctttttggta tattgttcat atcatcaaaa
    21421 gtttttgcac ccttatatat ccaagagaat atttgacttc ctctaaaggg cttttcatct
    21481 atagttttca taaattcttt aagttcatct tcagtaaaat tttttaatac tatctttttc
    21541 ttttccattc tctcactacc ttattctctt taattttgct atgaaaaaac catctatacc
    21601 atgaatatta ggatatatct ttaaatatcc tttatcttga ttgtctaagt ctacatttac
    21661 tgtatcaatt ggaacaaatt caaagttgtg attttcttca acaaaagaag taactatatt
    21721 tatattctcc acatcttgaa ttgtacatgt actatatact aaagttccac caactttgac
    21781 atatttagat gcattttcta aaattttctt ttgtatagaa gtgatgtctt ttaactcttc
    21841 ttctttctta tacttaattt ctggtttacg tcttattata ccaaaaccag agcaaggaac
    21901 atctgctaaa acataatcaa atttacttat actattttca tcaatctcag aagcatcaaa
    21961 tctttctaca aacacatttt taagccccaa tctatttaca gtagagttta taagctttag
    22021 tttatgctca aaaatatctc tagctactac ttgaccagta ttgttcatta aagtagctaa
    22081 gtgagtagat ttccctccag gagcactaca tacatccaaa acaaatgagc cttcttttgg
    22141 attaattact ttccctacta tcatagaact tatatcttga attgtaaata aaccagcctt
    22201 aaataattca tttttttcta tatttttcat tttttcgact ttaatagctt cttctaccat
    22261 aggaactttt aaacatacaa tacccatttc acttaatttt tcaataagtt cttctctact
    22321 tattttaagt gtattcgttc ttatatagat actaggcttt tcattatttg cttccaacaa
    22381 atcttcagca aattcttgtc caaatttatc tatccagttt tttataatcc aagagttata
    22441 ggaatacttt atagataagt attttacact atcttcctca gttatgtcca ttatagtctc
    22501 tttagctctt atttcatttc taagaatagc atttatgaaa ccagaagatt ttttatcata
    22561 tttcttagat aattttacag tttcattaac tgctgcataa tctgatatac tatctaaaaa
    22621 taaaatctga tatgttccca ttcttaaaaa gattttaaca taagttgaca ttttttttac
    22681 ctttattttt gaaagtttat tgattatata atctaaataa tatttatttt ctattactcc
    22741 ataaattaac tctgttgcaa gtcctctatc catatcactt atttctaaat ttttaaaatg
    22801 cttatttatt gcaatatttg aataattgtc atttttttct atatcacata atactttaaa
    22861 tccaacttct cttgcatcca tataaatttc tcccttttat taaacataaa aaagggttgt
    22921 ttctaaacaa cccactttac ttttagtcat ttcttctttg agctattagt aacaatctaa
    22981 gtaattgaag tattgaaacc aatgctgctg caacatatgt taaagctgct gctgaaagta
    23041 ctcttctact ttgtcttgac tcactttcat ctataatacc taaattccca agttgaacga
    23101 ttgctctact tgaagcatta aattctacag gcaatgttat tatttggaat aacactgaag
    23161 ccgaaaacaa tagtatacca atttttaaaa atggaccagc cataataaat cctaaaaata
    23221 ttaaaaacca agatatactt gaagcaaaat tcactactgg tactaaacta cttcttattt
    23281 gaagaggtgc ataaccttta gcatgttgta tggcatgacc acattcatgt gcagctactg
    23341 caacagaagt tatagatgtt ccataatata catcttctga caaccttaca gcctttcttc
    23401 ttgggtcata atggtcactt agatgccctc taaccatttc tatctttaca tcatacaaac
    23461 catttgaatc aagtactctt cttgctgttt gctctccagt atatcctcga cgtgtattta
    23521 ctcttaaata cttatttgtt gttgaactca ctttaaattg tgcatatata gtaagtaata
    23581 tagctggaat taatacaacc attgttgggt caaatcccca aaaaccgcca tatacagggt
    23641 acataaataa cactctccta aaatatattt ttattataca tcctcttaat attcacttaa
    23701 cttaaaaaca gtttaattac aaactaatat attttttcct gttaaaaagc ctatagcttt
    23761 ttcaatatcc atcatgtcta cattagtatt tacacaaggt ccattaggtc ttttgttaaa
    23821 tacacctaaa acaggaattt tcttaatatc ttgtattcca gatgtcaaat ctctttcaca
    23881 tgcaacagct acaacagctt taggtttagt gtccattata atttttctag ctagagttcc
    23941 tcctgtagct acaaatattt ttacattagt tttttccttt agcttaatta attctcctat
    24001 gttgcatctt ccacattctt tacaattatc tatatcatta gtaactttta atttacaact
    24061 attctcttga atacaatgag gtattaaaat tattatatcc tctggattaa aattatattt
    24121 attactgtat atatattcat tatttaactt tatatatatt cttctaatat cactttttga
    24181 cataccaaat gatgatgcaa tgaaagatat aataggaaat aatccactga caatattaaa
    24241 atttattttc attatatttg agttaacata ctttccttta attactctat aagtaactac
    24301 tgttgaacat agtattataa gtattagtga tattattata atatttatca tcaaggagaa
    24361 tatttgagtt aaacttatta taaaaaaatt aacaactcct atcaaaattc ctaatattaa
    24421 aatcaaaatc ccaacacttg ttaaatactt ctttatatct gtcatacttt tcacctaacc
    24481 caatactaaa ccagtttcta tagtattccc ttttatatat tcaccaacca acattctctt
    24541 tttattcggc atctgaattt cttcaattaa aagtacatta tctatagtac ttacttttat
    24601 cccatctttg cttacatcaa ttattgtacc tacatctttt gtgctttttt catctaacac
    24661 tttagttttc caaactttca ttatgacatc attataggta gtataagcac ttggccatgg
    24721 atttactcct ctaactaaat tgtgtatttc tctggcactt tttgaaaaat ctatgttacc
    24781 taatgattta ttcattattg gcgcatagga aaattcttca tgattttgta cttctcttgg
    24841 agcatttcct tcttcaatta atcttaatgt ttcttttaaa gtttctgctc ctatattcat
    24901 cattttatca tgaagttctc ctgctgttat attttcatca agatttactt ctgtctttag
    24961 tatcatatct ccagtatcta atccttcatc catatacata gttgtaacac cagtcttttc
    25021 ttcaccattt attattaccc aatttatagg tgccgcacct ctatattttg gaagtaaaga
    25081 aacatgaaca tttatacatc caagtttagg aatctctaat atttcttttg gaagtatctg
    25141 tccaaaagct acaactacta ttacatctgg atttaaagat ttaattttat ctataaattc
    25201 tttatctcta gcctttactg gttgatatac aggtatatta ttttcaattg ccagttcttt
    25261 tactggactc atacctagtt ttttacctct tccttttggt ttatctggtt gagttacaac
    25321 acccaatatt tcatacttct catctattat tttttgtaaa catggaactg ctatatcagg
    25381 agttcccata aatactattt tcatcaaatc aactcctact acttttctat tttgtcaaca
    25441 aataaaattc catctaagtg gtctatctca tgacaaaatg ctctagctaa aagttcttct
    25501 ccctctaact ctattgtttc accatttcta tttaaagctc tgacctttac ataatttggt
    25561 cttctaacat ttcccgcttc tccaacaaca cttaaacatc cttcctcatc tatttgctcc
    25621 ccagatgttt ctattatttc aggatttata agttctataa gctcttctcc aatatctatt
    25681 actactactc tttttaatat tccaacttga ggtgcagcca gtccaacacc atctgcatca
    25741 tacatagttt ctgccatatc atctaataat tgtattatct tttcatcaat tttttcaacc
    25801 ttttttgatt tttttcttaa tactggttct cctatttgaa ctatttgtct taaagccatt
    25861 ataattcctc ctaaatttat aatacactgt ttggattaat atctatagat acattgatat
    25921 tcttatcaaa tatcaaatct cgttttgtta tacatatata ttttattata ccctttaaga
    25981 gattaatttc aatattttca tctttaaaga gtatttgcca tctataattt tgatttattt
    26041 ttgatattga acatggattt ggacctaata taaatcctaa atcatttata cccctttttt
    26101 ctaataaata aatcaatgat gcatgcatat tttttatatt ttttatcact aatctttcat
    26161 cttcaccact aacaactaca cttaacatat tattaaaagg agaatatcca aatgcttttc
    26221 ttatttttat ctcatcttca taaaaaccct cataatcata ttcaatagca tgcttaatag
    26281 catagtgttc agtgtcataa gtctgaagta ctacttttcc ctctttatca gctctccctg
    26341 ctcttccaga gacttgagtt atcaattgaa atgtagtttc aaaactttta aagtctggaa
    26401 aatttaatat catgtctgca gacaaaatac ctactaaagt tacattctca aaatccagcc
    26461 ctttacttaa catctgtgtt ccaataagta catctgcttc tttatcttta aatttattta
    26521 gtatctcatc taaagcacct ttttttgaag ttgtatcttt atccattctc aaagttttta
    26581 tatctggaaa aatatatttt aattcctctt caattttttg agttccaact ccaaatggct
    26641 taacataagt acttttacat tcaggacact cttttggaat ttctttctca tatccacaat
    26701 agtggcatct tccagtattg cttttcttat gataagttaa agatatatca caattttcac
    26761 attgaaacac atatccacac tttctacaag atacaaaatt tgcataacct cttctgttta
    26821 aaaatagtat tacttgatta ttttcttcaa tcgcataacg tatttctttt tgtaatttca
    26881 aactaaatat acttctattt cctttatcta actcatcttt catgtctaca acttcaatgt
    26941 ttggaagagg cttatcattt gctctacttt ttatatttat aagtttgtat tctccagatt
    27001 ttgccctata atactcttca attgagggcg ttgctgaacc taaaataaga gttatattat
    27061 tttttaatgc cataaatcta gcaacttcta tagcattaaa ttttggattc ttctcagact
    27121 tatatgatga ctcatgacat tcatcaatta ttattaagcc taaggaatta aaaggtgcaa
    27181 ataaagctga cctagctcca attaacactc ttactttacc tgctttgaca gctttgtaaa
    27241 cgtcatgttt ttctccttca gatagtttac tgtggaacac tccaactaaa tctccaaacc
    27301 tactctttag cctatctatt gtttgaggag ttaatgctat ctcaggtact aagaatatac
    27361 tgtctaagcc ttgatttaga gcaaattcta ttatttccat gtaaacttca gtttttccac
    27421 ttccagttac tccatgaatt aagtatggtt ttttatcatc tacaaacata ttcgacttta
    27481 tctcatcaac tgcttcttgt tgctcattgt ttaattttat actttttagt acggatttgt
    27541 aaatactttt tggctctcta taataatcct taaattctag ggttattagc tttttcttac
    27601 ttagagaatt tatactttgt tttgaagcat ttaataaatc caataaatca tttatctcta
    27661 cattttcatt atttttaaga aaacttaata tctctttttg tttacttccc acatttattt
    27721 tattttgctc tatataatcg tcaatcttat cactttctaa actcaaagat atataacata
    27781 ctttcttttc atttttgtga tttttatatt cccaacataa ttttataatt ccatttttat
    27841 tcattgtgta caaagaacta tttaagtttg gtatatattt taacttatca accttaattt
    27901 tacctttact atcaatcact ttctctacta tttctctatt tttatcactt aaagttgata
    27961 ttttttcctt caattcaata tcatttaatc cacttaaact ttcacctaat aggactactt
    28021 tataattatt taatttgtat ccctttggat atatcaaatt tatacattct atataagtac
    28081 acaaatatct atttttcatc caataaacca actctaaatc ttcttttcta aatatcggat
    28141 tttcatctaa tatatcaata atttctttta tttttatttt ttcatctaag ctatctgtaa
    28201 attgaaatac aaaggcttct gttggtttat taccttttcc aaatggtact aatattctgt
    28261 gcccaatttt tattacatca gataaaaata caggaatttg atatgtaaat aaattatctg
    28321 tatatatagt attacttcta actattacct ttgcatattt tttcattata aaacctctac
    28381 ttaaatttaa tatattgttc atattttaat atactttaca agatattaaa atctcagaat
    28441 ttataagcaa tttcaagtta ttaatattaa ctttatttta ataattaact attaattata
    28501 ttttatactt tatgacaaaa taaatgctga aaactacaat ttaactgaca tttgcgagtt
    28561 tttactcgct aaaattaaat tgcagctttc agccacttta gctgtgataa aatacacaaa
    28621 tatcatattt aaaaaaggtc ttatttctca agcaacgctt taactttatc taaaataaca
    28681 ttggctactt cttctttttt catcttagga tactcagtaa tatttccctc tacatctatt
    28741 atttttacaa tattagtatc agctctaaaa ccagcacctt ctttagttaa atcatttgcc
    28801 acaataaaat ctaaattttt cttttttatt tttcctttgg catgttctat aaggtcatta
    28861 gtttcagctg caaatccaat tagtatctta tcttctttta tttttcctat ttcataagca
    28921 atatcataat ttctacttag ttctattgat aaatcatcat tcttcttttt aatttttttg
    28981 tcagaataag tttttggttt ataatctgca actgctgcac tttgaattac tattttattt
    29041 tcacttaaat ttgatactac tgcttcatac aaatcttgtg ctgactctat ttgaacaaat
    29101 tttttaagat tttgtggaat agaaagattt gtaggacctg atattaatgt tacatcagca
    29161 cctctagcta tagcttctct tgctatagaa tatcccattt taccagaaga cctattagtt
    29221 aaatatctta ctgggtctat actctctaca gttggaccag ctgtaactat catactttga
    29281 ccttttaaat cttgctcttt agtaagatta gtcaaaactt cctctactat tatatctgga
    29341 ttagctagtt tacctgttcc aatatctcca catgcaagcc ttccactttc cggttcaata
    29401 aatttatatc caaagctctt taaagtttgt atattttttt gaacaattgg attttcatac
    29461 atattagtat tcatagctgg tgctataaga acctgtgctt ttgttgccat aacagtagtt
    29521 gtcaacatat cgtcagctat accatttgca atcttgccta taacatttgc acttgctggc
    29581 actattaaga ataaatctgc tttttttgct aatgatatat gttcaacttc ccaagttttt
    29641 ggttcttcaa acatatcttc tactacataa ttttgactca gcgattgaaa tgtaagtggt
    29701 ttaacaaatt ctgttgctga ttttgtcatt ataacatgga tatttgcatt tagttttttt
    29761 aacttactta caacatcaca agccttatat gcagctatac cgccacttat gccaattaca
    29821 acagttttat cttttagcat gaccttactc ctcttctgaa atttgttggt gttgctcagc
    29881 atgatgtcta gcttcttcta tctctatttc ctcttctgtc aataatctat atgttatttt
    29941 tccacttgca acttctttag ttgctacaca tacaggcttt tccttagttt tatttgaaac
    30001 atatggttct tctccatcaa ttaattttct tgctctcttt gaaacagtcc ccactaaata
    30061 gtatctgttg tctatttttt ctagtacctc attgatagat ggttttaaca taattataat
    30121 tcctccttaa atttctctat tataatattt ttatatctgc taactttatt cttttcagat
    30181 gatattatac cttctatttc tttagcagat gtttttacat cttcattaaa tataaaataa
    30241 tcataatcct taatcatttt aatttcttca tatgcacagc taaatctctt ctctatttca
    30301 gcttctgttt ctgtacctct tccaacaatt ctatttttta attcttcaag tgatggtggt
    30361 agtacaaata taaatactcc ctctgggcaa acttctttta tttgttttgc tccttgcatt
    30421 tcaatctcca gtaatacatc ttgtcctttt tctaaacatt ccattattgc cgcttttgga
    30481 gttccataaa aattatcata aatttgagca tactccaaaa actcaccttt ttctatcatc
    30541 tcttcaaact tttccttact tatgaagaaa taatttactc catcaacttc tccagttctg
    30601 ggttttcttg tagtagctga tacagaaagt tttattgtat cattttcttt aagtagttct
    30661 ttgcaaatag taccttttcc tgcacctgat ggtcctgata caactagcaa taatcctttt
    30721 ttcacaaaca tttaagcatt ccccttctaa tattgtattc ttactctata ttttgtattt
    30781 gttctcttat tttttccaat tcgcttttta cttctactac taaattagtt atatttatat
    30841 cagatgactt cgaacctata gtgttagttt ctctattcat ctcttgtatt aagaaatcta
    30901 tttttctacc tatagagtcg tctttaaata tagtattttt aagttgccct atatgacttt
    30961 taaatctaac tatttcttct gttatactgc ttttatctgc atatattgca acttcttgtg
    31021 ctaatctatt ctcatctatt atacttgggt catccagtaa ttcacttatt ctcaaattca
    31081 atttttctct ataatcttct acaacactac ttgaatattt ttcaatctct tctatatgat
    31141 tttttaataa atcacatctc atggcaatat cttcagctaa ttttttacct tcttcacttc
    31201 tcatttctct taatttgatt aatgcatctt caactgcttg attcaacatt gaccacaata
    31261 aatcttcatc ttcttccttt tcttctattt tcacaatatc aggaaacttt gcaacattca
    31321 taacgctaat atcatctata atatcaaatt tattttttat ttcttttagt atgtctatat
    31381 actgagatgc taatccctca tcaaaattta agtttacatc ttctttgcct aataagtcaa
    31441 actttatgta taaatctact cttcctcttt ttacataatt ttttactaaa tttctaactt
    31501 tatcctctaa aaatgaaatt tttcttggaa gacgtatgtt tatatctgaa tacttatgat
    31561 ttatcgtttt acactctact aaaaagtaat aattatcatc cttgtattct cctcttccaa
    31621 aaccagtcat acttatagcc attaattaaa cctccaaaat accttcacat atttttactg
    31681 ctggacctgt catataagag aaatctccta catctatttt aactgttcca ccttgagacg
    31741 ttacatttac actactttct accatattaa gtaaattgca cactattgct gatgcagtca
    31801 taccagtacc acaacctaaa gtatatccac aacctctttc ccaagtataa acatgtatat
    31861 tatacttatc ttctaccttt acaaaattta cattcgtttt ttcaggaaat attttattat
    31921 tttcaatctc ttttccatat ttacaaacat catctacatc taattcatct actataacta
    31981 ctgtatgagg aacccccatc aacatagaag taactttaag ctccctatct aaaaccttta
    32041 tactttcttg cacaaaacgt tctttatttg taagtacagg aacgtcctta gctataaaac
    32101 ttccttttcc catattgact cttatagagt ttatttctct attagtaaga tttactttta
    32161 tatcttttat accatctaat gtatctactg taaaactttc ttttttaact atacaattat
    32221 cataaacaaa tttacaaaaa catctaaggc catttccaca catagctgct cttgaaccat
    32281 cagaattata atataccatt tctacatctg caacttttga atctttcaca actaacaatc
    32341 catccgctcc tacagaaaat cttctatggc atactttttt tgctaaagca gtataatcag
    32401 atggatttat ctggtcgaat cttccatcta ttgctataaa atcatttcct attccatgta
    32461 gtttccaaaa tttcataagt atcgctcctt cgtaaattaa cgcttaaact attataacat
    32521 aaaaaaattc ccataaactt ataatttatg ggaaaagttt tgtaatgaca actataattt
    32581 gaggatgtga gggagagttg ccattacaat tagggtaatt atattatgtt tttaagctag
    32641 ttctttctat gtttatatat taatatttct atatgaattt tatgtatgtt ttatttaaac
    32701 tgtctatgaa ttttttaatt aaacatctgg taactagcta taatccttct agtagatatc
    32761 tattaacata cacctattaa ttctttaagt gtttttaaaa catagtctaa atcttcctta
    32821 gtaatatcta catgagttac aaatctatat tcaccatttt ccattttatt aatttttata
    32881 tttctttcaa aaaattcttt tattaaaaca tcctctttta taatatcttc actcatctta
    32941 aaaaatacca tacttatatc tggattaaca ttgtttactt caatgccatc aattttattt
    33001 aattcacaag ctaaatattt tgcattttca tggtcttcat tcaatcttaa agtcattttt
    33061 tcaatggcaa ttataccagc tgctgcaact atacctactt gtctcattcc cccacccata
    33121 actttttgct ttcttctagc ttttgctata aattctttat ttccagcaag tatagaaccc
    33181 attggtgcag ctaaaccttt tgacacacag aacataacac tatcacaaca ctttgctatt
    33241 tctttagctt ctacacccaa agttaatgct gcgttaaata atcttgctcc atctaaatgt
    33301 actggtaagt tatgtttctc agctattttt ttaatttctc ttaaattatc aagactcaca
    33361 actgttccac ctgaatatgc attttctaca catataagcc ctgtctgtgg ttcatgtatg
    33421 tcatctcttc taattgcctt ttcaacaagt tcaggattta gagctccact ttcgtcttca
    33481 tctatagttc taagctgaac tccagctatt acagcaggtg ccccaacctc atgagtcaca
    33541 atgtgataac ctttaccaat aattatttct tgccctctta ggcaatgagt aaatagagct
    33601 aattgattcc caaaagttcc acttggaagg aaaatagcat cttcttttcc aactttagct
    33661 gctgctaatt cttcaagttt atttacagta gggtcatctc taaagattga atctccaaca
    33721 ggagcctttg ccatagcttc tctcatttcg tcagtaggca tagtaacagt atcacttctt
    33781 aaatcgataa atctcatttt ttcaaccttc tttcatattt atatactata gaaccttaaa
    33841 attgattttt tctgtaaagt tcatatactt tcatagctta tactctacac aataattata
    33901 ctatatttac tttatattta atctacttta aattattaat tttaaaaata aagtttcctc
    33961 tctaataaat ataaataatt atacaattta aatattaatc tctattgttt aaattccccc
    34021 tagtcacaaa gcgtatatta tgtgtataat taatttactg actcattttg gtcaaagaaa
    34081 ggggtgctat aaatggcatt agatggatta gttatacatt caatagtcga tgaattatca
    34141 tcaaaactta caggtggaaa aatagataag atacatcaac ctgaagatga tgaggtaatt
    34201 tttaatataa gaaataataa agaaaatttt agattggttt taagtgcaag tgcctcaaat
    34261 cctagagttt atcttacaag taattatcaa aaagaaaacc ctctaaaagc gcctatgttt
    34321 tgtatgttac ttagaaaata catacaaggt ggaaatatag tagaaatttc tcaaataggt
    34381 tttgaaagaa taataaaaat aagtgttgaa tctttagatg aattaaaaga aaagacagtt
    34441 aaaaatatta tgattgaaat tatgggaaga catagcaaca taataataac tcatggtgaa
    34501 gaaaataaaa ttatagattc tataaaaaga gtccctttta gcataagtag agttcgtcaa
    34561 gttttacctg gtcatgatta ttcattgcca ccagaacaaa acaaactcaa ccctcttgat
    34621 gatatatcta aggatttgtt tattaaaaac ctagaggaat tggaaggacc tatctttaag
    34681 tctatatatt ctaaatttct aggtataagc cctattatag ctaaagaaat ttgctacaga
    34741 gcaggtgtaa atcaaaatgc tatcataaag gatatatctg atgaacaatt tgatgcttta
    34801 cacaaagtat tttgtaattt attcaatgat ataaattcta acaaatactc tccttgcatt
    34861 attatagata aaaaggtgga taaggtagtt gatttcagtt gtataaacct tacattattt
    34921 agcgatttat catatataaa taaggatagt atgtctcgta ttctggaaga tttctataga
    34981 actaaggata ttaaagatag aattaatcaa cgttcatctg atttaaagaa gagtatatct
    35041 gttaagcttg atagacttta taataaactt aaaaaacaag aagaagaatt atcagaatcc
    35101 gaaaatgcag acatttataa gataaaagga gaattgatta cttcatatat ttatatggta
    35161 gaaaaaggta tggaaagtat tgaagttgct aacttctatg atgaaaattg taatgatgta
    35221 acaatagaat taaataaaaa cttgacacca tctgaaaatg ctcaaaaata ctttaaaaag
    35281 tataacaaaa tgaaacatgc taaagtcgag atatctcatc aaatttcctt aaataaggaa
    35341 gaaatagatt acttagaaaa cataatttta agtattgaaa actgtgaaaa tttagctgaa
    35401 ttacaagata taaaagaaga acttgctaaa gttggataca tcaagactca aaagaaaaac
    35461 agtaaaaagg atactatccc atctacaaaa cctcatgaat ttgtgtcttc tgatggattt
    35521 aaaatattgg ttggtaaaaa caataagcaa aatgactatc ttacactaag acttgctgat
    35581 aatgatgact tatggatgca tacaaaaaat attcctggtt ctcatgtaat aataaagtgt
    35641 gctggtaagg aagtccctga taatactgta tttgaaggag ctatgctagc agcattcttt
    35701 agtaagtcaa aactttcttc tcaggtgcct gtagactata ctaagagaaa aaatgtgaaa
    35761 aaacctagtg gttctaaacc aggtatggtt atttatgaaa ctaacagtac tatttatgtt
    35821 actcctgaag aagaaacagt agccaagctt aaggttaaat ctgaataaat tctgcactaa
    35881 atacaaaata aatgttagac aactacacat tatcattcta aataaaaata gtggccttct
    35941 tataaagtac aataataagg ccactttcta attagcttac ttttaatttt ctaacaaaat
    36001 acttttctgt tttaataact atacttatat tcccaacaaa tattttcagt cttcttatat
    36061 agatgtaatt aaaaagttaa cactaaaagc tattttttaa tttattgatt tgttttagta
    36121 attcattata ttctgattca tacaattctt tttttagatt atctttttct atagataaca
    36181 tagatataac agttgtaagt ctattttcta atactagaag attttctttt ttgatttggt
    36241 tttctctact aggagttttt ttatttctgc taattgtata ttcgtcataa ttacaatcaa
    36301 actcccttat tttagcatct tttatctcta taatatagtt acaaatatgt gatacaaata
    36361 ctctatcatg agacactata agcatagttt tatcagtatt tatcagtgcc ttttccagtg
    36421 cttccataga ttttatatct aagtaatttg ttggttcatc aaatactaaa aaattattat
    36481 cttccaatat tattttacat agtgctattt ttaccttttc tccaccacta agtactttta
    36541 cttttttgta gacatcatca cctttaaacc caaataggct taagtttatc cttataaaag
    36601 attcatcaaa tgaactatta actttagtat tgtatagaac actcttttcc tcatctaata
    36661 aactttgatt ttggtcaaaa taacctactt ttaccttgtt atttattttt atattgtcat
    36721 ttttatcagc caatatttct tttatcagag tactttttcc acacccatta tcacctaaca
    36781 atgctatctt tttacctctt tttatcttaa aggaaacatt atctaacagg agcttatttt
    36841 ctaactttag agtcatatct tttacctcta ctagattttt gctaattatc tccataccat
    36901 cttgcatctt aatgttcatt tctttagaaa ctttaggttt attctttacc tcaagtttat
    36961 caattctgct ttttatagcc ttcacatttg agtccaactt tttcttatta gtctgaccac
    37021 ccattttgtg caacctagct tctgaattac ccattctttt tggtgttttt cttatgccat
    37081 cacttaaagc ttttttatat aaaagagctt tttcaagcct ttttttctct ttaacatatt
    37141 cttgatactc aaaatcagct ctttttactt cttcatcttt ttgcattaaa taatcagtgt
    37201 aattgccttt gtaagctttt agttttccat cttctagttc taatatagtt gtacataact
    37261 catccagaaa acgtctatca tgagatatta ataataatgc tccctcatgc cttttaaaca
    37321 tatcttccaa aaccccaatg ctttttttat ctaagtttga agttggctca tcagctatta
    37381 tgatattttt cttattactc agcgcatctg ctatttttaa cttaaccttt tcccctcctg
    37441 ataagtgttc ttcaaattta tctggagcat ttaaaagact cttctcctta ctatgactac
    37501 atgtttcaat attattttca ctctgactta tataagaata gctttctgta aggtaagtat
    37561 atccttcatc aatttctatt tctcccaata ttgcttttaa taatgttgtt tttccttgac
    37621 catttgaacc aactagacct attttgtcat tttctaatat ttcaagttta tctatatcca
    37681 aaattaattt atctgcataa tatttcttta aattctctac ttttactaac aacataaaaa
    37741 atccctcctt aacacactta aatataagga gagattctat aaataggcat aacaaataaa
    37801 cgtatagact ataatctact ctccttaatt taagcattgc aaataaagcc accaaaatag
    37861 gcttttcaaa aattacaata ctttaaatta taaaaaatag attatattct cattgtccta
    37921 gttaccttgc cctttctttc atttattttt aatcattata tcaacattaa ttacaaatgt
    37981 ctatagaaaa ttaactaatt ttagttattc aatatacaac ttattcttta aatttattct
    38041 tcttcaactt taaagtcctg attatttaaa attctgttta atacaattcc aacaattgca
    38101 gctaaactaa gaccagttat ctttactgta cttgttatag ggattccaac agaaatacct
    38161 ttattagata aatatgttgt tccaagacct attaataata taactgctat gattaatata
    38221 tttattttac tttctacaca agaactgtcc cttatagttt ttaatcctac ataagttatc
    38281 atcgaaaata gcattatact aattccaccc ataactgaac ctggtatact ttgaagaaat
    38341 ccaccaaact tgcctacaca tgcaagcaat atagcaaata ttgctgtacg tctaagtatt
    38401 gaagggtcat agtttttagt tatagcaagt actgctgtat tttctccata agttgtattg
    38461 gctggtcctc ctaaacaccc tgcaactata gtcgcaaatc catccccaag taatgttcta
    38521 tttaatccgg gattttctat aaagttttta cctactacag caccattagt agtcatatct
    38581 cctatatgtt ccataaatac agctaataca actggagata taatcactat tgctcctaaa
    38641 ctgaacttag gaactgtaaa gttaggtatt gcaaataaac ttgcttctgt aatagtagtt
    38701 atatctacta atcttaatat caaacagatt atatacccag aaaaaactgc tattaatatt
    38761 cctaattgtt ttataaatcc tctaccaaac ttattggtta aaattgctat tgctaaagtt
    38821 ataaatgcta tcacaaaatt ggctgaagcc atactaaaag ctgttggcaa taaatttaat
    38881 cctataacta ctatcatagc tcctgtaact tgtgcaggaa aatataattt aattttattt
    38941 acaccaacta cttttactat aatcgacatt ataatataaa ttaatcctgc tactattata
    39001 ccaccttgag catatgctaa atctccacca tatgcctctt tagctgctag tataactggt
    39061 ataaacgcaa aacttgaacc taaaaaggca ggtacttttc cttctgtaca aaaatgaaat
    39121 atcaatgtac caacaccagc acagaaaatt gcaactgacg gattaaaacc tgtcaaaatg
    39181 ggaactaata ctgtcgctcc aaacatggct aatagatgtt gtaaagacat tatcgttttt
    39241 ttcataaaaa cctccaaaat tattatatat aaataaatcc tctgtttaat taatatcttt
    39301 taattaatta tcattcccta gattctattt tttaacctct atatacttat tatataattt
    39361 atcattattt tacattttac gacatcaaaa actcaaataa aggagaataa aaactacatt
    39421 aagactcaca tccataaaat tataatattt attttgtgca atctatgtaa gctttatcct
    39481 cctccctgac tattcaatgc taagctttta tataatactt aaaaataatt attctttgat
    39541 tgtaactgaa tcttctccat caatttctaa taaactgaca gatataattt catgtctaga
    39601 agtaggtaca ttttttccta cataatctgc tcttataggc aactctctat gccctctgtc
    39661 cactagcact gctaattgta ttgatttagg tcttcctata tctataatag catctagtga
    39721 agctctcaca gttcttccag tgtataaaac atcatcaact aaaactactg tcttatcatt
    39781 tacattaaaa tctaaataag ttcctttaac tacaggttca acatgaattt tttccaaatc
    39841 atctctatac aaagttatat caatatctcc tgtatctact tttgttcctt ctatttgttc
    39901 tattttctta gaaattctat ttgcaattgg cacacctcta gtctttattc caactaaaac
    39961 tagattttct acacctttat ttctttcaat tatttcatga cttattctag taattgctct
    40021 tgctattgcc ttttcatcca ttaattgagc tttttctacc atatcataat tattgtcaaa
    40081 gatataatat atctatttga caaatctact cctttctttt aattttttat aaatttattt
    40141 ttatttaaaa tttcaattta aacaacaaaa aaacttctca tcacaagaca agaagctctt
    40201 atataaaaaa tatacagtgc aatttagcaa ttgtcttacg atatctctgt atcgtttaaa
    40261 gataattttt taatctatca aatcaaatta tatatttata tttcaaattt ttcaagcttt
    40321 tttaaacaaa atactttaat ataagatatt ttatttaaat ttcactaaat ttatttactt
    40381 atataaaaac aaaaaatgat ttataagtat tatacaaata gttattttat ctttttaata
    40441 acttccttaa aatactcagg taattctgaa ttaaattcga tatattcctt agtagtagga
    40501 tgtataaatc ccaacttctt agcatgcaaa gtttgtcctt ttaatttaaa tttagtttct
    40561 tttggaccat atacataatc acctaaaagt gggtgattta tagacaaagc atgaactctt
    40621 atttgatgag ttctaccagt ttcaagccta gctctcatat gtgtaaactt atcaaatctt
    40681 tctacaactt caaagtgagt gattgcattt tttccatctt ttactacagc catttttaat
    40741 ctatccttag gatttctccc tataggttta tcaacagtta ttttatcttc tttaaccaca
    40801 ccatagcata taaattcata ctccctagtt atagtatgtt cctttaactg ttctgctaga
    40861 aaattatgtg cataattgtt cttagctatc ataagaagac cagaagtatc tttgtctatt
    40921 ctatgaacta taccaggtct aataacgcca tttattgatg acaacttatc tttacaatga
    40981 tataaaatcc cgtttactaa cgtattttca tagtttccag gagcaggatg gacaaccata
    41041 tcctgaggtt tatttattat taagacatca tcatcttcat atacaatatc tattggaata
    41101 tcttgaggta aaacttctaa tactttaggt tctggtatct ctataacaat attatcttcc
    41161 tctttaacca gatatctagc tttttctact ttattattaa cctttacttt tccatctttt
    41221 ataatttttt gtatataact tcttgacata tcacctaatt gttctgctag ataaatatca
    41281 agtctaactt cttcttcctc ttcaagtact aaaaactctt ttacttcatc cattatatca
    41341 cctactttta ctttcaaaaa ataaaacata tatacataaa aacacagttc ctacaactac
    41401 aaatacatca gctatattga atacatattc ccatataatt ctaaagtcga agtaatctac
    41461 tacaaaacct aatcgtactc tatcaattag atttcccaat gcaccagata taattaatat
    41521 aattcccaac cttccaaata tatgtacttt ccttgtatta agatagtata gtccaaatac
    41581 tgttgcaagt aatgcaacaa ttataaatat ccattgatta ttttgtaata atccaaatgc
    41641 tgcacctcta ttttcgacat aagttaaatg aaatacatta tttattattg gtattgttga
    41701 tacatccacc aaattattca atacccatat tttagacagt tggtctaaac ctatgagtag
    41761 aattattatt aatatatata gcaatgattt ttccccctat aaattattta aaaaccaatt
    41821 ttatttgaag cacactatta ttattataca aaaaaaatgc tctaaagagc aactttatta
    41881 aaattgtatt ttcttaataa agctagaaca aaatttaaaa tagtactact ttttttatat
    41941 tgtagatttc tacatattta aaatcatatc attatgtata aaaaatttaa aaataccata
    42001 ctaatcaata ttttttgtgt attttataga ttaaagatta atgatgtctg taatttaaac
    42061 ttacaatcac cactaatctt caaacaaata tttttacttt tgcacttgct tatttttatc
    42121 taaatgttgt ataagttcag atactgttac gaatttatat cctctctctt ttaatttagg
    42181 aattactact tctaaagctt gtatagtttg tgatttatca tttcttttag tgttataatc
    42241 atgtaaaagt attatattac cattttggac ctttgtaagg atagtattta taattgcatc
    42301 tactccaggg ttagaccaat ctctagggtc taagtttgac caaagaatta tattcatgcc
    42361 tttagaaact ataatatcac agacactttt actcatggct ctatatggag gtctaaatat
    42421 ctttggttct actcctatta cactttttat aatattttgc gtatctgtta tttctttttc
    42481 aacactacta taactatttt ttgcaacatt tatatgtgta aatgtatgat tccctatttc
    42541 atgcccctca tcatattgtc tttttaataa ttctttgtta tattctactt tttctccaac
    42601 tacaaaaaaa gttgctttta catcattttt ctttaatata tcaagtactt gtggtgtaaa
    42661 atcctcatct ggaccatcat caaaagttaa tgctaaaatt ttttcatcct catttccttt
    42721 ttttattatt acatcttcat aatcgtcttt tatattgtca tttaaactat atgcttcttt
    42781 tgaactatct tgattatgtg tattatgatt atatgtatat acacctacta tagataataa
    42841 acatatacat ataccccata ttattttctt catgtcatta cctcttttct aattcattct
    42901 agcaatatat tttataatgt cagtttttta atctctcaat attccatttt tatttaaatc
    42961 agttaaattt gttaggtctt ctgaataaaa gttagaatct tctacatcag ggttttgcat
    43021 tgcatcacct aataaattat tttctttctt tgcacaatca ttacataaac ttgtatctgg
    43081 caatatatcc aatctttcta aatctatttg attatgacat aaatcacaaa tcccatatgt
    43141 tccattctct attttagata atgctaagtc tatttgatac aatcttccct cttcatgatt
    43201 tattagactg ttttgcatat tttgcatata taaatctgtt cccatgtctc ctatatgatt
    43261 atcataacta gataattctc ctgatgaata cttttcactt gtatgtttag ttgtatctcc
    43321 aaataaagta ttatctttca tatcctctac taaattagtt aaattttctc tttctttcaa
    43381 taatttatct ttatattttt tagtatccat ttttaacacc tctaatttta atatttacat
    43441 cataaaaata gtatgtggaa aagtaaatta aacatacaat aaaaataaga tttgattcga
    43501 aaaatggaat gtctcaaaat gaaattttta gttcatttaa ccctcttttt tatatgaaat
    43561 caaatatatt tttatccttt cagcaataaa aaagagactt atctctattt tgagatagtc
    43621 tcttctttga acataattta aatacaattt tttaattttt atagttatta ttttactaac
    43681 ttgccaattt atgattattt tgttctttaa tatgttttgc ttttttaaag aataaaagac
    43741 caagaattat tgctacaata acacctattc cattagatat attaactggt agtctaaatc
    43801 cttcttttgc ttgcattata taactaaatg ttactacagt cataaaaagt gctggtaatg
    43861 tagttatata atggttttta tttgctttga ctaaatatgc agaaccagtc cacaacatta
    43921 tcattgcaag tgtttgattt gcccaagaga aatatctcca aattatatta aaatctataa
    43981 atgtaagagc aacaccaact gcgaataatg gtaaagctat taaaaatcta tttttgactg
    44041 catcttgatt ataattcatt gcatctgcta ttgtcagcct agcacttcta aatgctgtat
    44101 ctccagaagt tataggacat gccacaactc caagtatagc taaagctcct ccaataggcc
    44161 ccattaatcc aacagatact gtatttacta ctgttgctgc tccaccatca ttaaatatca
    44221 cattaagttg aggtatgcca tggaaatatg acatggctgc tgctgcccaa actaaagcta
    44281 ttataccttc tgcaaccatt gacccataaa atactggtct tgcctcactc tctttctcaa
    44341 cacatctcgc cataagtggt gattgagttg catgaaaacc tgatattgct ccacatgcta
    44401 ttgttataaa taagtatggg aataaaggtg ttccatttgg attcatattt tgtaaattta
    44461 tatttggtat gttatacccc tttattatta atcctccagc tacacctact gccataatta
    44521 ataatgctgc tccaaataaa ggatatattt taccaatcaa tttatctatt ggtaaaacag
    44581 tagccataat ataataaagt attatcactc caacccatat ttgtgcgttt acacctgtca
    44641 atgtctttaa taatcctgct ggacctgtta caaatacaac tccaaccaat actaaaagaa
    44701 taacactaaa tattctcatt gctatttttg caccatttcc tagataaagg cctaccaact
    44761 ctgatgcaga tgtacctttg tttttcattg atagatatcc tgaagcaaaa tcgtgtactc
    44821 caccagcaaa gattgttcca aacacaatcc ataaaaatgc tgatggtcca aataatgctc
    44881 cttgtatagc tccaaatatc ggacctaacc ctgctatatt tagaaactga attaaaaaga
    44941 ttctcttcca tttcattggc acataatcta ctccatccct acaagctata gctggagttt
    45001 gatttttgtc attggttcca aaaacctttt ctacaaaagt accatagaca aaataaccta
    45061 ctataagtac tactattgaa cctaaaaagc ttaccataaa ttcatcccct tagtttttat
    45121 ataattgctt tataaatttt tatgagttta agaaaactat ttccagttca aatagtaata
    45181 cttttttatg ctaatataaa tattaattac attaagtgca tatttaagta catgaaatga
    45241 ctttatatat gcattaacag cctaaattct tttactttgc ttctacttac agttacttca
    45301 taatcactat tttttaattt taatatgtat gtattattaa accatggtat aatttctttt
    45361 actttggtta agtttacgat ataagaccta tgtgttctaa aaaatgtttt atcatttata
    45421 agattttcga cttctgatat gccttctttt aatataaact tttctttctc agtatatata
    45481 aatgtctgcc tttcattagc ttcacagtaa tatatatcat caatatctat tacaactaat
    45541 ttatcacctt tccaaaggct aattttatgt gttatttctt ctatctcctg atttactgct
    45601 tccttcttat atttgtataa attactattt acattaaata gttcaatatc actcatctca
    45661 cttttttcta atttattcag catagaaata attctctctt cagaatatgg tttcaatata
    45721 taatcaaata catccaaaga aaaagcatct actgcataac tttcatatgc tgttataaaa
    45781 acaattttag gtcttgattt aaactgattt aatgtttttg caagtagcat tccatcaaga
    45841 tgaggtatat ttatatctaa aaaaattaca tctattttat tttcctgaat aaagtctaac
    45901 acctctatac cattggtaaa ttcacttact acctcgattc cacttttatt ttcaataaaa
    45961 tatctcaatt cctttcttgc tggaaattca tcttccacta ttatagctct catacttcta
    46021 ctcctttaca taaaatacta tcaaagtccc attatctatt cttcttatat taagccctct
    46081 tccatacatc agtttaagcc ttaaatgtac attataaagc ccaatcttat tttctggcat
    46141 attatcttga tatacattat ttataatttc ctcacttata cctataccat tatcctctat
    46201 tgatattctc acagtatttt ctaatgaata cggtaacttt tttatggata ttttcactac
    46261 accagctcta ccactttcta aaataccatg tattattgca ttttccacta atggttgtat
    46321 aatcaaactt ggaatcttta tatttacatc ttctatatca taagatacag ttagtaattc
    46381 tccaaaccta gctttttcta tctctacaaa agatttaact tgttcaatct ctttatttat
    46441 atcaattaag ttatcactat attcaagatt atatcttaga taagttgata aatttattat
    46501 taactctcta gccttatctg gactaaatct tataaatgaa gctattgtgt ttagggaatt
    46561 aaacaaaaaa tgtggattaa tttgtctttg aagtgctttt atttctgctt tatttctcgc
    46621 ttctatatct tttttatctt tctcaatccc ctctactata gatataacaa atcctattcc
    46681 aatctgccca actattaaag gtaaatatat tccaccgatt atttgaattg ctaaagaatg
    46741 tggatatgat attaagtata taagtaatat agtaaaactt tcagaaatca tgcctaccaa
    46801 tattccatac attactctat gttgttttgg tatcctctta tatagaaatc ctgataatac
    46861 acctgctagt atacttgata aaagacatgg aacagatgtt atccccccaa tatccataaa
    46921 atatctatga atccctgaaa aaactcctgc tgtaatacct accatcggac caaataaaat
    46981 gccacctgat actatagata ttattctagt gtttactatt gaccccatat aatttatacc
    47041 actataagtt ccaaatatgg ctaaaaaagt aaaaactaat gctatacaga ccaagtcatt
    47101 aaaactatat tcttcctttt gaaatatctg cttaaatatt tttaactttg ttattagaag
    47161 aaacaatact acaataaggc ttgtcttttc tattaatgcg attaaaattg atgttttcat
    47221 aatctccctt taaaaaataa atttttacac actctaaatt tattatggtt gttataaatt
    47281 acatatttga agtaatccta tcacaaaact ttccacattt aatcttttaa ttaaataaga
    47341 aatagttgta cttctattaa caactaatac tagctagcat aagcttgtaa taacttgtag
    47401 ttattattaa ctttacaatt ctagtattta attttatact ttagaaatct cttttcttag
    47461 aaataatact ttcgaatatc atataataca atattatgta gattcttact catacaacat
    47521 atttctttaa aaattttata ctattctttg ttcaaatatc tcatttgatt taattgtgtt
    47581 aaacacacat tatcatctct ctgttatata tttattatat agccgtatat cgataaagta
    47641 aataaatccc atatttaaaa taatatgttt gacaataaat tattataatg tatatttacc
    47701 ataataattt gtcaaccttg aaagttactt ctataattat tgttaaataa tt
//
LOCUS       DAMJVG010000024        47354 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.024, whole genome shotgun sequence.
ACCESSION   DAMJVG010000024 DAMJVG010000000
VERSION     DAMJVG010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 47354)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47354)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47354
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.024"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            216..1766
                     /locus_tag="PC512_001468"
     CDS             216..1766
                     /locus_tag="PC512_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF2441224.1"
                     /translation="MRYKKRNIDKSSELSFQSLAKYFITFYIVIILIILSMFCINTIW
                     VMKKDNQDLLSTTSNRIEDRVGETIKLLNSLSKDNYIIDNSVNGIDKSKELSMYSDEF
                     GYMMICFVDKNIIVWDEEGGNISLAGRDYMQKLFATKKYQVTDSFAAGADGKTLNYTI
                     ASPIIKNGNVDGCVFAAIYFDEIKDILKQGKGQQQQNFILFGSENQIMNLTSDETAYG
                     EKYMKLSQKTKYLGTNAKKVEKDMFNNKSGDYWAFENGKLYFMSYKPIKNTNWSLFCK
                     VNFLDIFALNLIPMGAILSVITLVFIILICMEKSFMKKRMEVIDMLLGSVQELEKRIY
                     QTERPSEVDFKEIIQLTSKGLTDGLTGVVTRTVFFDQIYNRVEMEENDKLSVISFVDL
                     DDLKCINDLYGHEIGDMVLKNVGYVLREYEIKYNGLIGRYGGDEFVMLLSGFTSREEV
                     EDLLDEIAIRLHTEVLTDDGIIQTHCSVGAVVCSVKDNKDIDNLLKQADEALYYVKRN
                     GKGNYHLV"
     gene            1792..4494
                     /locus_tag="PC512_001469"
     CDS             1792..4494
                     /locus_tag="PC512_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF2441225.1"
                     /translation="MKNVSKKFFVCTIIVLITFLCFSKFAIYVFDKQEKKETKVVENM
                     LNVYKNNIILNLTEKFNYSKDLTSVLVSNNYSIDKLKPIADEILKNNSCIYISVVEKY
                     NVAAFFSNSVKKDIINTPIQELNYSYSLANSIKGLVVEGPSKDQFSNGDVFLITNPIY
                     KNGEYWGEITVALDAKKVVDSFNLNKLKESGFEYELWRVHLDNGSKSTIEISTKDFNF
                     SKSHEIKFKLPTVWTLSIVYKNGWNNKNIDFIVFVILLIISILIGVMTFIYIEKKSIS
                     KELNQQSLKNLETGILNREGFLIKLQEHLNRKNNEIVLLYICITNYSKFAPVMSFEKR
                     QDYLTHIVKNLDNYIKSSHFIARISEEGFVLALEENCDKNELLNIEKGISLELLRKIK
                     VENKQVFLTIGYGSSRCVDDRKDAESLLLSAIEDYERRFPAMSPIHDFTKKCEDMLDE
                     KKQIVFGEYPDLEINKLSKVIYKYYKKVQRIMYKDYNIDIGNRRGYMRDVEVLIDYNS
                     ERMLYLFLIDICKFGKFNELFSIEIGDVILKEVSNKLKTIFSNYLYRINGDVFLGISI
                     DKESYLDTLHKVNEVFNSSLSVEDVLFDVKCNIGICQYPYHGENPYDLLEKVQIALEY
                     AKKDVKSNVKVYDKELTEEIYHENNIIKDLKKGLEEQTLEVWYQPIFNVSKNCYIKAE
                     ALIRLRNKEGGYYSAYEVITYAEKHGLIKDVGLYVLKKACDVTTKIKDKNIDFEQMQL
                     NLSAQQIVHKQCANDILSCIENCGLDKKYISVEVTEKVLMETFEIVNVTLDKLKKEGI
                     SIALDEFGSGFSSINYLANLPIENLKIDKELVEQITYSKKQFELLKTIVQITKINGMD
                     IVAEGVETKETLDLVVTSGVNLIQGHYFSEPLSEDKFIELMIEE"
     gene            complement(5000..5665)
                     /locus_tag="PC512_001470"
     CDS             complement(5000..5665)
                     /locus_tag="PC512_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441226.1"
                     /translation="MKGNIVQYNFADIEEEVYSLDYAIAWNTDEENVNIIPFTNKFCK
                     ESIESFCLGKINNFVEILNEGFVENHHYVHLDKMISVPKKKVNLVYQQDTHGYLLRDD
                     NDNLIPAKITSEQSKSISSKMELFCAGEEKCLINILLKADPSYILDVDSIKDKNILNL
                     GYESIDRYKEYNFDDDKILIFFINKKRYSVIMKKTNNSDNDLVSRNNAIKELFTNKAG
                     NLN"
     gene            6009..7439
                     /locus_tag="PC512_001471"
     CDS             6009..7439
                     /locus_tag="PC512_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HDF2441227.1"
                     /translation="MDIKNKIKSIFLPEKNDYLDDEEFEYDIENNEEDLKEDNKVHLN
                     DLSRVKYDYRELKDIENQTEEMCLLAVKQDGTIIEFVKDKTYKVCMEAVKQTYKSLKY
                     ITNQNEDICIEAVKQNYRALYYINNKTENVLIEAIKNASTYDVMEVFKFVEEQTEDVC
                     LAFIERASKNDVAEILKGIKEQTPAICLEAVKKDGKSLAYVKEQSNSICLEAVKENYS
                     ALSCVKEQTEEICIEAVKQNDFALYYVNEQTEKICMEAVKRSYMALQYVNKQTEEICL
                     EAVRIDGRALQYVKEQTEEICLESVRQNGKVLQYVKKQTENICIEAVRGSFEELEIKE
                     ILSYVKIPTERIFVEAVKQNGKILKYVENQTELICLEAVRENYNALAYVKEQTEKICL
                     EAVNQSYEALKYVKEQTEEVCLKAVKQDYRMLKYVNNQTEKICLEAVKQNYRALEFVD
                     NQTEKVCLEAVKQNRKALQYVKQKQS"
     gene            7807..8385
                     /locus_tag="PC512_001472"
     CDS             7807..8385
                     /locus_tag="PC512_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HDF2441228.1"
                     /translation="MFKRYAEKMTSVLICNNMIDNNESKVYSYGFEILIAFIVNITTM
                     LFIGFLFGKFTYVLFFLMCYCPIRQFSGGYHADNYFRCLLTFIFIILSTILIIENINI
                     DLFKNIIMIIASVSWVGICVLCPIEHRSNPISDREKLVYKKTAIFISTVVLLITILSL
                     SLSIFVDYFTYSAFAMFWIFVMLVLGKLKAKV"
     gene            8415..8561
                     /locus_tag="PC512_001473"
     CDS             8415..8561
                     /locus_tag="PC512_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic lactone autoinducer peptide"
                     /protein_id="HDF2441229.1"
                     /translation="MKKFIVRFMKFASSLALSTAILSANSTCPWIIHQPKVPKEISNL
                     KKTN"
     gene            8866..10245
                     /gene="scfB"
                     /locus_tag="PC512_001474"
     CDS             8866..10245
                     /gene="scfB"
                     /locus_tag="PC512_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioether cross-link-forming SCIFF peptide
                     maturase"
                     /protein_id="HDF2441230.1"
                     /translation="MSMIHKFSMNGYNIVLDVNGGAVHVLDDVAYDLLDFYKEKSKEE
                     ILEILKSKYQEEKINEAYEEILNLEKEGLLYTEDTYQYHPSFVHREPVVKALCLNVAH
                     DCNLKCKYCFAAQGDFGGEKELMSFEVGKAAIDYLIANSGSRKNLEIDFFGGEPLMNF
                     EVVKQLVDYGRSVEKDYNKNIRFTITTNGVLLNDEIIDYINENMHNVVLSLDGRKEVN
                     DNMRPTLNDKGSYDITLPRFKKLVEKRAKDKYYYIRGTFTRDNLDFSKDVMHFADLGF
                     KLTSVEPVVGDESNPYALREEDLPKIFEEYEKFAVEYADRQLQGDGFKFFHFMIDLNQ
                     GPCVIKRITGCGAGNEYLSVTPNGDIYPCHQFVGNEEFKMANIFDEEIVLPENLKNMF
                     REAHVYTKEECKQCWNKFYCSGGCHANAINFNNDISKPYELGCEMQRKRTECSIMIQA
                     KLMLEGATN"
     gene            10274..10771
                     /locus_tag="PC512_001475"
     CDS             10274..10771
                     /locus_tag="PC512_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HDF2441231.1"
                     /translation="MIRDYLEDKPLIDESVFVAKSADVIGNVKIGKDSSIWYNAVVRG
                     DEGPITIGENTNIQDCSIVHGDTETIIGNNVTVGHRSIVHGCKISDNVLIGMGSIILD
                     NAEIGEYTLIGAGTLITSNKKFPPGVLIMGSPGKVVRELTEEDKKYIDESYEWYLEAA
                     QNQKY"
     gene            11069..12733
                     /locus_tag="PC512_001476"
     CDS             11069..12733
                     /locus_tag="PC512_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HDF2441232.1"
                     /translation="MRISYRNLKRYREIGYVLIKYGFSFIVERLNIEGIAYKIPLFDP
                     PEEIKNMTTGERMKRVLEELGPTYIKIGQILSTRKDLLDQDIIDEISKLRDDVEKFDS
                     NIAIDIFKEEVGLSIEEIFLEFKEEPIAAASIGQVYEGVLKTGEEVIVKIQRPNIEKI
                     IKSDLEILRTIANTLKDLKKDFNLDLVQMIEEFQTQLMRELDYTFEAINATKFSRIFK
                     NSDEVYIPKVYSEYNTKKILVMEKVNGTKLSDVEKIRRLGYNTKTIVEIGVRSFFTQV
                     LSHGFFHADPHPGNIFVVAKNKIAYIDFGMIGIIDNKTLNQLNEIALAGVEKNVDKII
                     YLLIEMDALNGEADIKGLRQDLLYLIHYYYDISIEKINVTDILNELFRFFRQYKIVMP
                     AQFVTLAKTVITLEGTSRTLNTDFSFGSMGKEFMKHHYKSKFNPKNVVLSSRQNVEEI
                     LLDIKTIPKQLKAILKNIERNNIKMQIEDVKMTRLENCIIELTSQISLSLVLASIIVG
                     SSLIIASPNIENNIWIKFTAIAGFFISFIIGLCLVIRSIRSKYKKD"
     gene            12746..15196
                     /gene="recJ"
                     /locus_tag="PC512_001477"
     CDS             12746..15196
                     /gene="recJ"
                     /locus_tag="PC512_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HDF2441233.1"
                     /translation="MKKWILKYKGKIEESEFSKKLNISPEICQILKNRGICTEKDSEI
                     FMNPSLDYLRDPFLMKDMQKAVDRIKLAVEKNEKIWIYGDYDVDGVSSTSILCLYFKS
                     IGYNVDYYIPNRLEEGYGINEDAIKLISSRGCDLIISVDCGITSVSEVNTANDLGIDV
                     IITDHHECQSEIPSAFAVINPKQEDCNYPFDSLCGCGVAFKMIQALTPKEEFKTSMYN
                     YLEIVTLATICDIVPLIDENRIIVKNGLKSMKEGKNIGLRELIKVCGVESDKIGSSHI
                     GFAIGPRINASGRLGYSYLGVELFTTQSQEEAVEIASILEEKNNERQMIEAKMYHEAE
                     EMLKSNSRYNDDKVLVLAKEGWQHGIIGIVASKLTEKYYKPTILLGIENGEATGSARS
                     IKGFNIFEALIKCKDLMTKFGGHEQAAGLSLDSDNVEILANEINKFADYNLTEDDMIE
                     NVNVEFELQENVINLNLVEELHKLEPFGLNNPNPRFIVRNYILKDLKVIGKNQQHLKL
                     SIEKEKSYECIGFNMSHLKSMYKVGDKVDVLFQLDENNYMGNRKVQFLLKDIRLARPK
                     SASNDKLSLKLMSKIIPKDTQSLYNISVSDFELFDGNTDINIFDYFEKDTLIISNSIN
                     GFYRAMSDISLIDLDFNINYNIIEDDSKNTDKLELIFSPNIDKIDLKRYNNIILYDYL
                     YNKGEYSYIYENKREESEIIKYYNKTDLLYLKNVVSNIVPSRDEFITIYKQALIKKEI
                     DLDMVNIRETFNVIPLKFFTILNVFRELNLLDFNLNYEKNSVLIRILPKPQKKLDLNE
                     SLILNNLKNLEKQYNSSY"
     gene            15209..15721
                     /locus_tag="PC512_001478"
     CDS             15209..15721
                     /locus_tag="PC512_001478"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HDF2441234.1"
                     /translation="MDLKNFIRNIDDFPKPGIDFKDVTTLFKDGDAFKYAVDSIVEEL
                     KDKDVDLVIGPEARGFLMGTPVAYALGVGFVPIRKPGKLPGEVESYEYGLEYGTDTLE
                     IHKDAIKKGQKVAIVDDLLATGGTMEAAAKLVEKLGGEVVSMQFLIELKFLNGREKLS
                     NYDVNSLIKY"
     gene            15795..18002
                     /locus_tag="PC512_001479"
     CDS             15795..18002
                     /locus_tag="PC512_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003229747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HDF2441235.1"
                     /translation="MHDKELQEIIEKIKVYAPNANFEMVEKAYNLAKKAHEGQYRKSG
                     EPYFIHPLAVANILIEMELDIETITAGLLHDVVEDTEYTYEDIKKEFGKEVADLVDGV
                     TKLGQIKYRSKEETQSENLRKMFLAMAKDIRVILIKLADRLHNMRTLKYMPPEKAKYK
                     AKETLEIYGGIAHRLGISKIKWELEDRALRFMDPEGYYDLVSRVSMKRSQREDYIQGI
                     VELLKDKFKDLSIPCDVYGRPKHFYSIYRKMQKKHKTFEEIFDLTAVRILVDNVKDCY
                     AVLGIVHTLWRPIPGRFKDYIAMPKPNMYQSLHTTVVGPDGEPLEIQIRTHEMHNIAE
                     NGIAAHWKYKEGISSKESKVEEKLQWLRQMMEWEKDLKDPQEFMDALKEDVFNSQVYV
                     FTPKGDVIELPAESTPIDFAYRVHTNVGNKCVGAKIDGRIVPIDYKLQNGNIVEVLTS
                     SNSNGPSRDWLNIVKTPNAKSRIRQFFKKERREENVDRGNTILEREFKKHDIPQKDPL
                     VEKYMALVAKKFNQPSVEDLIATVGYGGIMSSQVVSKVKDLYLKEVKKAKKEQQIQEE
                     DLNKHNISETEYSKKRKKNASQGIIVKGLDNILVRFAKCCNPLPGDEIVGYITKGRGV
                     AIHRADCPNANNNGDFFQNRLVEVSWSSAGKGKFEAEIQIKAIDRRGIVNEITHIVAM
                     DKLSLNGINARKGKDSIVSINLLVEVNDTEELKILMKKLKAIPGVESIYRMTN"
     gene            18027..18476
                     /locus_tag="PC512_001480"
     CDS             18027..18476
                     /locus_tag="PC512_001480"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003517065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HDF2441236.1"
                     /translation="MRAVVQRVSSSKVTVDENTIGQINKGLLVLLGVTHDDKSSDVDY
                     MIDKILNLRIFEDENDKMNLSLMDIGGELLVVSQFTLYGDCRKGRRPGFSNAARPELA
                     NNLYEEFVKKAKDKGVTVGTGQFAAHMMVELTNDGPVTILLDSSKSF"
     gene            18491..19105
                     /locus_tag="PC512_001481"
     CDS             18491..19105
                     /locus_tag="PC512_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2441237.1"
                     /translation="MIIKKFVDSYFGVNTYVLGDEKTKKCAVIDPGGSLVETLSFVKE
                     NELNIEYIILTHGHGDHIGYVKDIKEKTGAKVVAHVDEKELLNDKNKNLSYTMRCGAQ
                     EFDADIYVNDKDKLELGELKMTFLHTPGHTQGCMCIRVEDEMFTGDTLFAGSIGRTDL
                     YSGDFNQMEKSLKKLCKYEDAVRVYPGHGPTSTLGVEKKTNPYM"
     gene            19196..20752
                     /locus_tag="PC512_001482"
     CDS             19196..20752
                     /locus_tag="PC512_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coproporphyrinogen III oxidase"
                     /protein_id="HDF2441238.1"
                     /translation="MLYVFLKGHDYKYEVAELIKLFTSEFKFKDSNANNNIESKHLIN
                     RLIYENGVLFSSTEYYENGNLKYESIQNIENMNLEFLDGFDSSKTIEEFLNSLDSESK
                     RNFKKLCKENIKKSMFLVLKQVFNSYVPWGILTGIRPVKIVHNLMDKKLDDNSIRTIL
                     KDNYFIIDEKIDLALEIAKRERLFMYPIDKNKISLYVSIPFCPTRCVYCSFPSNSLKQ
                     FGHLKREYVYKLIEEIKGFAKVIKDTKKEVETLYIGGGTPTTLDEEELDLLINSLFNE
                     LDLSKIKEFTVEAGRPDTITEQKLRVLKKHNVSRISINPQTMNDDTLVKIGREHRVSD
                     LVDCFNMARRMGFDNINMDIILGLIDEDLNMVKNTLEEIKKLSPESLTVHTLAIKRAS
                     NLNINMDRYKEHLTQYEEMVKMIDLSMKYAKDMGLNPYYMYRQKHMLGNLENIGYAKE
                     GYECIYNIQIMEEKQSNYALGAGAISKFVYVDEDRIERVENVKNVEQYIERVDEMIKR
                     KKEEVYKNVD"
     gene            20742..22004
                     /locus_tag="PC512_001483"
     CDS             20742..22004
                     /locus_tag="PC512_001483"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HDF2441239.1"
                     /translation="MLTKAPRGTKDITPKEAYKWRYVENKFREICALYGYEEMVTPIF
                     EHTELFKRSVGDTTDIVQKEMYSFKDKGDREITLKPEGTAGVVRAFIENKLYADTQPT
                     KLFYVTPCFRYERPQAGRQRQFHQFGIEALGSDTPSMDAEIIALAVQFFNEVGLNDLV
                     VSINSVGCPVCRKEYNALLKEYLDSKADILCDTCNERREKNPMRVIDCKNPTCKENIK
                     DIPFIADHLCDDCKSHFDKLQEYLKEMNINFVIDKTIVRGLDYYRKTAFEIISNDIGA
                     QSTVCGGGRYDGLVEQLGGPKGISGIGFGLGIERLLLTLEGNGIEIENPQSTDIFIVT
                     IGEEANTRSFKLLKDLRQNHISADKDHIERSVKAQFKYSDKINSKFTIVIGDDELKND
                     TATLKNMKTSEQTTVKLSTLVEELKQKL"
     gene            22078..23865
                     /gene="aspS"
                     /locus_tag="PC512_001484"
     CDS             22078..23865
                     /gene="aspS"
                     /locus_tag="PC512_001484"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HDF2441240.1"
                     /translation="METLKGLKRTHYCGELREKNINEEVVLMGWVQKKRNLGGLVFVD
                     LRDTSGLCQIVFDTDVDKEAFEKAEKLGAEFVIAVKGKVCERQSKNPNMLTGDIEIFA
                     TELRLLNKSETPPIYIKDDDDVSEALRLKYRYLDLRKPSMQRNLKLRHKVMNITRNYL
                     SNNRFCEIETPFLIAPTPEGARDYLVPSRVNPGKFYALPQSPQLYKQLLMVSGMDRYF
                     QIVKCFRDEDLRADRQPEFTQIDCEMSFVEQEDVMSMIEGLLEAIFKEVLDVELALPL
                     PKMTYAEAMSKYGSDKPDTRFGYELTDISDVVCNCGFKVFADATQPGKSVRGINVKGK
                     ADDFTRKQISSLEEHAKTYRAKGLAWMKVGQEGVTSPIAKFFNEEEMNAILTRMNAEV
                     GDLLLFVADKNSIVFDALGQVRLEVANRLNLLDKNVYNLLWVTEFPVFEEDEETGTFS
                     AMHHPFTSPMDEDLDKLEEGDKSSLRAKAYDIVLNGYEIGGGSVRISNSDVQSRMFKA
                     LGFTEERANEKFGYLLEAFKYGTPPHAGLAFGLDRLVMLLAGTDNIREVIAFPKNQNA
                     VCPMTNAPTLAEDEQLEELSIKVDIKDNE"
     gene            24324..25556
                     /locus_tag="PC512_001485"
     CDS             24324..25556
                     /locus_tag="PC512_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HDF2441241.1"
                     /translation="MQEREELVLNPVPKEERVGWLAPLFNMLGSNIAISELMVGGTLI
                     LGMTLSNMIITSIIGNLILVAIIMIQGYIGYKEGLNTYVLAKGAFGEIGGKYLISLLL
                     GITSFGWFGVQAGVAGLSVQKIFPSVNLTLVTVILGLFMVVFALYGFKAMAKFNYLVI
                     PPLMILMVWGVFKAFSTYGVEAIYNYTPQTTMSMVEGLNIVVGLVIVGAIISPDQLRY
                     TRRVKDIWIISFLGLGIISLFQQVAAGVMSMGAPTWDITEVLANLGFGWVAFVILILA
                     SWSTNVSNAYSGGLALKTIFPNVKRNVLTLVAGLIGTIIAATGIIFKFQSFLSFLGIA
                     VPAIAGIMWCEYYFIQGRTYKHREGINWIAVISWLIGFAASYYSSKINFLIPPINGIV
                     VSMVIYYILMKCFGIKDK"
     gene            25570..26376
                     /locus_tag="PC512_001486"
     CDS             25570..26376
                     /locus_tag="PC512_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase"
                     /protein_id="HDF2441242.1"
                     /translation="MGRKVKIGIIQQHSVLGDVKKNIEKAVEMIDDLGKQGADIICLP
                     ELFATGYNLESLGGVKTLELIREHNKYIEESMSEAAKRNNVYLISPYGTLEKGSTHVY
                     NSAVIFDRKGKIMGEYCKNHLWSLEAVYFKGGEKVEVYDADFGRFGVMICYDAGFPEV
                     SRELTLKGSEIIFIPSAWRIQDEDMWDLNVSQRALENTVYTVGVNLVSNDSNLILFGK
                     SKICNPRGTVITQLDTYREKYVLSEIDLDEIKKYREDIPYLKDRKSSYNI"
     gene            complement(26488..27357)
                     /locus_tag="PC512_001487"
     CDS             complement(26488..27357)
                     /locus_tag="PC512_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF2441243.1"
                     /translation="MDLLHLKYFQTVARMEHITKASHKLNIAQPALSKTISSLEKELG
                     VQLFDRKGRYIVLNEYGRLFLKRVDSILDLVESSKKELQDTSLENSGEVKILSPAAAN
                     VLPSLLSNFRKLYPNITFNVSHTLPSSYKKSDFDLYISSSFTKLNSENSITLTCEEIL
                     LGVSINHPLSLKDEVYLSEVSDENFIVITKGENYREVIDILCESANFKPKIAFESDSP
                     YTIYALIKSLQGVGFICGKSWGLSQDPEIKLLHIKDIEFKRYLNLSWFSENYESKAVL
                     LFKNFLINYFKNI"
     gene            27729..29156
                     /locus_tag="PC512_001488"
     CDS             27729..29156
                     /locus_tag="PC512_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp14"
                     /protein_id="HDF2441244.1"
                     /translation="MKLTKSISSMLCLSLVLSLSPVAYANEISRTTVENTLVGQDRYQ
                     TAVEVSKKGWSSANEAVVVNSESIVDALAVTPFAKLKNAPILLTEKNNLNSQTEKELK
                     RLGVKKVYIIGLSSSVSNDVQKQLESNNLTTDRVGGSDRYQTALSIAKKIEGLKDISE
                     IAVVNGYTGLADAVSIGSVAATNGMVILPVSDASGISSFKDFIESKNINKSYIIGSTN
                     AVSDKIKQSLPNSERIGGADRNETNGKVIEKFYTSNKLNNVFVAKDGMKNQNQLIDAL
                     AVGVLASKENSPVLIVGEQLSATQKSVFSNKNATSITQVGSGGNENAFKELKDLQANS
                     NNKRVMYVTNTDKVNIRNDATIEASVIGYLNNGDEVEVLDVLKTGWVKIKYNEGIGYV
                     SGSYLTNNKPDNSNENIKIKYVKEKDGLNVRKGPSTEDEKIGHLSYGSKVETIEMFAT
                     GWVKIKYNGGYGYVSNDYLSDTPVI"
     gene            complement(29233..29502)
                     /locus_tag="PC512_001489"
     CDS             complement(29233..29502)
                     /locus_tag="PC512_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441245.1"
                     /translation="MKFEYYYLIQDIAGILLAFIGLRMSIIGFRILSMRGLSINTLLI
                     VIKYCLFTIAGLNLLISKFGIRHWIWSVCMLIISIIINPRIKVSK"
     gene            complement(29505..30947)
                     /gene="nhaC"
                     /locus_tag="PC512_001490"
     CDS             complement(29505..30947)
                     /gene="nhaC"
                     /locus_tag="PC512_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HDF2441246.1"
                     /translation="MKMNTERKIPSFRYSLLVMLAIIALTSVGIVVFNASITTMFLLS
                     WLIVVPAAMKLGYTNDEIEAFGFEVGKDAFQSNLIILSVGVLIAAWIAAGTIPTVVYS
                     GLTIITPKYFLLTTLIVCSLTSVATGTSWGTLGTSGIAMMSIGTSMGIPLGLTAGAVI
                     SGAFFGDKMSPLSDSTNLAAAVCKTDVITHMKHMFYTTGPAYVICIVLYTVIGFKYSN
                     NTIDYVQINQIKDVLNSNFHIGLVAMIPIIFLLLLLLLQKPPIISILSSAIMGLIIAV
                     FQEGEKIGDVLNYMLSGFTIDTGFVYADKLLNRGGIMSMAETVLLVFVVFVIAGILQK
                     TGFLEVLLQPLITKIGKSRTKLVGSTFIVSYFANAFSSSMMFTSVFVGTLMSPIYKEF
                     KLKPQNLSRIIEDTATLGGPLIPWNSNAVFCAQTLGVSPLEFIPYCFLSWITPIISFI
                     YGVTGFTMLTYTDDEIEELEIFDTAQRRVD"
     gene            complement(30972..32138)
                     /locus_tag="PC512_001491"
     CDS             complement(30972..32138)
                     /locus_tag="PC512_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDF2441247.1"
                     /translation="MNYNFNEIVDRSNNFSSKWSEMEKKYGTNDLLPMWVADMDFKAA
                     PCIIDSLKNRLEQEIYGYTTRPDSYNESIVNWLDRRHNWKIKSEWLIYSPGVIPAISL
                     LINELTKANDKIMIQEPVYSPFNSVVKNNNRELIISPLQKLENGNYIMDYEDIENKIK
                     DVKLFILCNPHNPVGRVWTKDELKKLGDICLKHNVKIISDEIHSDIILKKHKHIPMAS
                     ISKEFEKNTITCMAPTKTFNIAGLQSSYVILPDEKYYKLLDDAFTRIDIKRNNCFSLV
                     ATEASYNNGESWLESFLEYLESNIDFAIKYINENMPKLKVRKPEGTYLLWVDFSALGL
                     SDEELESILVQKGKVALNQGNSFGIGGSGYQRINLACPRSMLEEALIRIKNAIN"
     gene            complement(32363..34483)
                     /locus_tag="PC512_001492"
     CDS             complement(32363..34483)
                     /locus_tag="PC512_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2441248.1"
                     /translation="MKQMELAIVSLKKDAGEIYENQIRQFLGDNLKINLYSFEEGNLK
                     FFKEKLILLSAYLKYDEIVKLSHYDAQIIVPKLTFEKNSIDMISKLEKDKIIYVYNLS
                     KDMAIETISLIHRLGIDNINILPCYPEIEFTPTDAVILTPGEKILPKFKNCEVIDLKY
                     RIIDLSCIVEIATKTKLKHLIKDDLIKKYVEKIIPTSYSTGELLLDANKFERQFDLLL
                     SIIDDGIICTNNDGIIQFYNHMARKILSINANEMIDSFVGDCIKDINFQSILTNKTPF
                     FEKLIKINHIDINLEIKHIQLNVFDGFILKMTKFSQLEKKQAKLRAQLVNSGNISKYT
                     FDDILGSSIQTINTKKIANKMAQSNSSILIIGESGTGKELFAQSIHSASRRKDGPFVA
                     VNCSTFQENLLQSELFGYDEGAFTGAKKGGKIGLFELANNGTIFLDEIGEMDLNSQSK
                     LLRVIQEKQVRRIGSNNVIDIDVRIIAATNRNLKELVSKNMFRRDLYFRLNVLPLKIH
                     PLRERPADIFEIFGSLKYDIPCNFILSEEVKEIFKMYRWEGNVRELRNLGEYFCYLEK
                     DIIEICDLPEYILDTIDSNYSRTVCNKVSNNIKKYQFNIGKDKNIMKYDYNFKRSLDE
                     YIFILDNLKKAYDLKERIGRKSLCKIALEENRFLTEQQIRNMLLELQDFGLVDILVGR
                     GGSIITSKGVEFLKNINRSNKLNS"
     gene            34716..35117
                     /locus_tag="PC512_001493"
     CDS             34716..35117
                     /locus_tag="PC512_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441249.1"
                     /translation="MKKCLYCNRDIKSPNNKLAIKYDDNMNIYPCRAECKEKIEEYIA
                     KKPTYKFINILEVLLGVGGIFCFLSKWTIAAQVVLGIDALVIFLFPLAGFKMNGKLSM
                     EQTKNQSRSIAISILAFIVIITVLYFKQIGK"
     gene            35160..35453
                     /locus_tag="PC512_001494"
     CDS             35160..35453
                     /locus_tag="PC512_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HDF2441250.1"
                     /translation="MEERKLAPNNEREALIKRLKRIEGQVKGIQKMVEQERYCVDILV
                     QISAIRSAINRVGTIILENHIKGCVAESIKHDDADKTEEMIKELMDTINKFTK"
     gene            35468..35908
                     /locus_tag="PC512_001495"
     CDS             35468..35908
                     /locus_tag="PC512_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SoxR reducing system RseC family protein"
                     /protein_id="HDF2441251.1"
                     /translation="MNQQGFIMEIVDDRTAKLKMQRHSACAACGKCATTNSAESKEIL
                     VEVDNTIGAKVGDHVEVSMDNMNVLKAAVMAYIIPLIALLVGTIGTYYILGAIGMTTG
                     VEAISGLVGICLTIICYLYLKKNDKKFRDSREFIPVITRILIDL"
     gene            complement(36000..36473)
                     /locus_tag="PC512_001496"
     CDS             complement(36000..36473)
                     /locus_tag="PC512_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HDF2441252.1"
                     /translation="MTDMSMILHFLFSGVATAGFAVFFNAPLYLLLPAGVTGGIGWIV
                     YVYLFNFTTNAVFAGFIAAALVSACSETLARKLKQPAIVFVIPGILPLIPGIGLYNTM
                     LSLIQKNYSLAMSKGTDALFLSAAIALGVLVVTSFVRTLNLLKIRKNFIPYRKSK"
     gene            complement(36473..37261)
                     /locus_tag="PC512_001497"
     CDS             complement(36473..37261)
                     /locus_tag="PC512_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HDF2441253.1"
                     /translation="MNQNEELEYKKNILKLALFVGELMIKNGAETSRVEDSVLRICRS
                     RGFYHVNIFTTPTVIIISDEKFDGFSFMKTIQSRGINLNKISLLNSFSREFVSDKEYD
                     IDNAIARLYEIQDVKPYPLWLFYSCTGIASACFACLLGGNYVLNFILTFIIAIFAAIT
                     YDKTMKISAISAFSCLVSSFLIALSGVLLVEIGILDDPKMLIVGAIMPLLPGVAFIKA
                     IRDLISGNLISGISRAFDAAMIIIAIASGVGFVLDTWYRIGGPF"
     gene            37589..38833
                     /locus_tag="PC512_001498"
     CDS             37589..38833
                     /locus_tag="PC512_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HDF2441254.1"
                     /translation="MFENLKKADPEIYESMKRELKRQQRNIELIASENIVSVPVMETM
                     GSHLTNKYAEGYSGKRYYGGCEYIDEVETLAIDRIKKIFGAEHANVQPHSGANANIGV
                     YFAMLKPGDVVMGMNLSQGGHLTHGAPVNISGQYYKFYEYGIDKDSGLIDFDEVRKIA
                     HEVKPKMIVAGASAYPREIDFKKFREIADEVGALLMVDMAHIAGLVAAGLHQNPCEVA
                     DFVTTTTHKTLRGPRGGVILCKEKYAKDIDKAIFPGIQGGPLEHIIASKAVCFKEALS
                     DEFKEYQVQVAKNAKALAEELIKRDFKLISGGTDNHLILLDLTNKNITGKAAEKRLDD
                     AYITANKNTIPFDPNGALVTSGIRLGTPAVTTRGMKEEDMAIIAEAIDLCLTYDEESK
                     ARTLVVGLTEKYPLYEEYNIMD"
     gene            39156..40253
                     /locus_tag="PC512_001499"
     CDS             39156..40253
                     /locus_tag="PC512_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-diphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HDF2441255.1"
                     /translation="MKVLILTGKFGMGHYSASNSLSEDIKAKFDNSEIIIKDIFEYIM
                     PNYSDKMYKTFSILVNRGSSLYNLFYKCAENGKKDIKFTFSDYFLNKLDTLLHEVQPT
                     VVISTFPFCSQLVSRYKEKYNSNLPLITCITDISSHSEWISKNTDCYLVASKSTKEEL
                     VFKGIDESKIKVNGIPVKKEFKRIEHVNHSTKKNILIMGGGLGLLPKSEQFYKELNSL
                     EGVKTTVITGNNKKMYYKLYGRYENIEVVGYTNEVYKYMKDSDLIISKPGGITLFETI
                     YSELPILAFNPFLQQEIDNASFILNNEIGRILGKNKKYYVDEIKDLIYDDATLKEMSS
                     NMKELKKQFDNNTLENILFSLDEQGACRECM"
     gene            40244..40942
                     /locus_tag="PC512_001500"
     CDS             40244..40942
                     /locus_tag="PC512_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDF2441256.1"
                     /translation="MYVVGLIIVVALIFLVHSIIPTYYNKLLNKEVLKNMAGENEIAL
                     TFDDGPDKRYTEKLLDVLKENDIQAMFFVVAKNAEKEPEIIKRMLRENHIVGLHSLEH
                     RNAWLYSYSYVKKDFIESTNIMKNLGVDVNYYRPPWGHTNIFSNSFVKKYNLKMTLWD
                     VMAEDWEKDSTVDIIINKLMSRTKENSIICLHDAGENSGGAVGAPERTIEALKIAIPK
                     LKASGLKFVTPERM"
     gene            40945..42009
                     /locus_tag="PC512_001501"
     CDS             40945..42009
                     /locus_tag="PC512_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HDF2441257.1"
                     /translation="MISKTEKKNKCLGSVAFLVLLMGITGYFVFRGQSVESLIKSLKG
                     ASPMFILIGFAMMFIYVACEGINIYLGMKALNQKTTLLKCMGYAFIGFYFSSITPSAS
                     GGQPAQVYYMKKDDINISYSSLILLVIVVIHQVVILAYSGIMFIMEREFILNNVSGMN
                     ILLIYGVITNVALVIGVIAIIFSKKLVNNFIISITNLLGKLRIIKDVESSRKVIISQI
                     EEYVKGAQYIKQNPKLVVQILVITIVQITSMFLVPFFVYKAFHLSTYTVFEILAIQSL
                     LNIAVSSLPLPGAVGASENSFMTLFKIFFPGHLLVPAMLLSRGISFYAFVAISGLICI
                     VVHVKSSEKVKAVKKVAYVR"
     gene            42192..42896
                     /locus_tag="PC512_001502"
     CDS             42192..42896
                     /locus_tag="PC512_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2441258.1"
                     /translation="MNKEIPKKILVADDNPEIREIVEILLTGEGYEVIMATNGEEAVN
                     LVDSTIDLIILDVVMPVKTGFVACNEIREKTTAPILFLTAKTQDSDKVIGFSAGGDDY
                     LSKPFSYSELISRVKSLLRRYYIYQGKEKEREPNILKTKELCVNLDTQDVTLNGEPVF
                     LTTIEYSILILMLKNRKKVFSSENLYETIWDEQYFYTANNTIMVHIRNLRKKLEKDQK
                     NPQYIKTAWGKGYYID"
     gene            42889..44211
                     /locus_tag="PC512_001503"
     CDS             42889..44211
                     /locus_tag="PC512_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2441259.1"
                     /translation="MINKIKPSKLGVILLIYVVISAAVAFILNIPFYSAVESIVKDVS
                     EGKVYFKREVNQLMDNFQTYVNNNGIRADDGDDIAKWNSDNWFVSMKIYKGNKVFYDT
                     LYYPNEVPDKSEENEFYSSPMARNYEIQFSDIKANIVVVALFRFRFQNFIEAISITFM
                     ALTFIITFLLLFSRKIKYLRKIEMGIKIVESGSLKYRIPVKGNDELSSLASSINEMSH
                     TLENQLIKEREMKNKNKDIVTSISHDVRTPLTSVICYLDLIKDHKYNSPEQLEQYIKN
                     VRSKAYQIKDLTDDLFTHFVNSGEEVSKGYEKINANEFIFQLLLDSSYTLEEKGFHIT
                     IENELYNQYHIYVDVTQFRRIFDNLCSNIIKYARKDKPIVFLIKVEDSKLLIIQKNRV
                     SNFSKNVESFGIGIKNCEKIVAYHNGSINVNSDDKEFAIEISIPAKES"
     gene            44398..45771
                     /locus_tag="PC512_001504"
     CDS             44398..45771
                     /locus_tag="PC512_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441260.1"
                     /translation="MVLTGAHYIYILFMVIILITMIMKKDTIVPCILGVFFMGLFFEK
                     NIFGAITAVFNSFIISLNELGPIILIIAIMVALSKALEANNAIQYMVRPFSRVIKNSN
                     TAFFVTGFVMLVLSWFFWPTPAVALVGAVFLPVAMRAGLPAIGVAVALNLFGHGLALS
                     TDFVIQGAPSITAGAAGVAVSYVINDGMILFWVMGIVTISMAFYTLKRDINKGMFREE
                     LKGFESEEVEAFNGKSKIATILVALGFLADIIAMYVFDLKGGDASALLGGTAVFLIII
                     INVINFGKDSLENVCENIIDGFVFGIKIFGAIIPIAAFFYMGEVAPLTGVFGKVLAPG
                     SQGLLSDIGIALSQTIPLNKFAVSGIETVVGAITGLDGSGFSGISLVGSLASVFGTAI
                     NASVGALAALGQISGIWVGGGCLVPWGLISAAAICGVSPIELAKRNFVPVITGLVVTT
                     IVAMFII"
     gene            complement(46143..47081)
                     /gene="pdaA"
                     /locus_tag="PC512_001505"
     CDS             complement(46143..47081)
                     /gene="pdaA"
                     /locus_tag="PC512_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="delta-lactam-biosynthetic de-N-acetylase"
                     /protein_id="HDF2441261.1"
                     /translation="MFRKVLHYLTLLSISIFFIVGCSNSQNNQNENQNKETQLQEDKE
                     KIDSGKDTSNVIVSDGTDKPSKATTNNDNNKLDVSSLDNTTLDWFYIPNNKHKTPEVN
                     TDIEFKFSDYDALYNGPTKDGQKTLYLTFDEGYENGYTTKILDTLKQNQVKAVFFVTA
                     PYIKENKDLVKRMVSEGHIVGNHSKTHPSMPTKTSNLKNFNDELYDVEKLYKDVTGKD
                     MVKFFRPPMGKYSEKSLAMTKNLGYKTVFWSFAYRDWDTDKQPSHEEATQKIMDNLHD
                     GSILLLHAVSKTSTEILNDFISNARKLGYEFELLEY"
BASE COUNT        18248 a         5277 c         8006 g        15823 t
ORIGIN      
        1 aattacgtat caaaatttgt aaaatgaata gatataatta ctaaatatgt gatagtattg
       61 gctataatag gatataaaaa ataatattgt aaaaaaaagt ttatatttag taatgaaaat
      121 ttaacgtttt acttgaaatt atgtgttttg taatgtatta ttaaggctct aataggaaca
      181 ttttcatcaa tttttctata gtgggggtag gaattatgag gtacaaaaaa agaaatatag
      241 ataagtcaag tgaactttca tttcaatctc tagcaaaata ttttataact ttctatatag
      301 taattatatt aattattctt tctatgtttt gtataaatac aatatgggtt atgaaaaaag
      361 ataatcaaga tttattatct acaacatcaa atcgtattga agatagggta ggagaaacaa
      421 ttaagctatt gaactctttg agtaaagata attacataat agataatagt gtgaatggca
      481 tagataaaag taaagaactt tcaatgtata gtgatgaatt tgggtatatg atgatatgtt
      541 ttgttgataa gaatataatt gtgtgggatg aagaaggtgg taatattagt ctagctggtc
      601 gtgattatat gcagaaactt tttgcaacaa aaaaatatca agttacagat agttttgcag
      661 caggggctga tggaaaaact ttaaactaca ctattgcatc acctataata aagaatggaa
      721 atgtagatgg ttgtgtattt gcagcaattt actttgatga gataaaggat atactcaaac
      781 aaggaaaagg tcaacagcaa cagaatttca tattatttgg aagtgaaaat caaataatga
      841 atttaacaag tgatgaaact gcatatggag agaagtatat gaagttatcg cagaaaacaa
      901 aatatcttgg aaccaatgca aaaaaagtag aaaaggatat gtttaataat aaatcaggtg
      961 attattgggc ttttgaaaat ggaaaattat actttatgtc ctataaacca attaagaaca
     1021 caaattggag tttattttgt aaagttaatt tcttagatat ttttgcatta aatttaattc
     1081 ctatgggagc tattctatct gttataactt tagtatttat tattttgatt tgtatggaga
     1141 aaagcttcat gaaaaaacga atggaagtta ttgatatgct tttaggttct gttcaagaat
     1201 tagaaaaacg tatatatcaa acagaaagac ctagtgaagt agactttaaa gaaattattc
     1261 agctcacaag taaaggtctg actgatggat taactggtgt tgtaacacgt actgtatttt
     1321 ttgaccaaat ttataatcgt gttgaaatgg aggaaaatga taaattatct gtaatttcat
     1381 ttgttgattt agatgatttg aaatgtatta acgacttata tggacatgaa attggggata
     1441 tggttttgaa aaatgttgga tatgtacttc gtgaatatga gataaaatat aatggtttaa
     1501 ttgggcgcta tggtggagat gaatttgtta tgttgttatc tggttttaca tcgagagaag
     1561 aggtggagga tttattggat gagattgcta ttcgcttaca tactgaagta ctaacagatg
     1621 atggtatcat tcaaactcat tgtagtgttg gagctgtagt atgtagtgta aaagacaata
     1681 aagatataga taatttatta aaacaggctg atgaagcttt atactatgtt aaacgtaatg
     1741 gaaaaggtaa ttatcattta gtttaatgta tgtggaagga gtttatatca tatgaaaaat
     1801 gtatctaaaa aattttttgt atgtactatt attgtattaa taacattttt atgttttagt
     1861 aaatttgcta tttatgtttt tgacaaacaa gaaaagaaag aaacaaaagt agtagaaaac
     1921 atgttaaatg tctacaagaa taacattatt ttaaatctga ctgaaaaatt taattatagc
     1981 aaagacttga catcagtttt agtttcaaac aattattcta tagataaatt aaaacctatt
     2041 gcagatgaaa ttcttaaaaa caattcttgc atatatattt cagttgtaga aaaatataat
     2101 gtagctgcat ttttttctaa ttctgtcaaa aaagatatta tcaatactcc aatacaggaa
     2161 ctgaattatt cttattcatt agcaaattct atcaaaggat tagtcgtaga aggtccttct
     2221 aaagaccagt tttcaaatgg agatgtgttt ttaattacta atcctattta taaaaatgga
     2281 gagtactggg gagaaattac agtagcttta gatgccaaaa aagttgtaga ttcttttaac
     2341 ttaaataaat taaaagaatc tggatttgag tatgaacttt ggcgtgtaca cctagataat
     2401 ggttcaaaat ctacaataga aatttctact aaagatttta atttttccaa atcacatgaa
     2461 attaagttta aacttccgac tgtttggact cttagcattg tgtacaaaaa tggatggaat
     2521 aataagaata tagattttat tgtatttgtt atattgttaa ttatttctat attaataggt
     2581 gtgatgacat ttatttacat tgaaaagaag tcgattagta aggaattaaa tcaacagagt
     2641 cttaaaaatt tagaaactgg tattttgaat agagaaggtt ttttaattaa gttgcaagag
     2701 catctgaata gaaaaaataa tgaaatagtg ttgctgtata tatgtattac taattatagt
     2761 aaatttgctc cagttatgag ctttgaaaaa agacaagatt atcttacaca tatagtaaaa
     2821 aatctagata attacataaa aagttctcat tttattgctc gtataagtga ggaaggtttt
     2881 gttctagctt tagaagaaaa ttgtgataaa aatgaattgc ttaacattga aaaagggatt
     2941 tccttagagc ttttacgaaa aattaaagta gaaaataaac aagtattttt aacgattggt
     3001 tatggctcat ctaggtgtgt tgatgataga aaagatgcag aatctctgtt actttcagct
     3061 attgaagatt atgagagaag atttccagca atgtctccta ttcatgattt tactaaaaag
     3121 tgtgaagata tgcttgatga aaagaaacag attgtatttg gtgaatatcc agatttagaa
     3181 ataaacaagt tgtctaaagt aatatacaaa tattataaaa aagtacagcg tattatgtat
     3241 aaagattata atattgatat tggaaatagg cgagggtata tgcgtgatgt cgaagtatta
     3301 attgattata attctgagag aatgttatac ttatttttaa tagacatatg caagtttgga
     3361 aaatttaatg aactgttttc tattgaaata ggagatgtta ttttaaaaga agttagtaac
     3421 aaattaaaaa caattttttc taattatcta tatcgtatta atggagatgt atttttaggc
     3481 atttcaatag ataaagaatc ttacttagat actttacata aggttaatga agtatttaat
     3541 agttctttaa gtgtagaaga tgtacttttt gatgtaaaat gtaatattgg tatttgtcaa
     3601 tatccatatc atggtgaaaa tccatatgac cttctggaaa aggtacaaat tgcattggag
     3661 tatgcaaaaa aggatgtcaa aagtaatgtt aaagtttatg ataaggaatt gacagaagag
     3721 atttaccatg aaaataatat tattaaggat ttaaaaaaag gtctggaaga acaaacacta
     3781 gaagtttggt atcagccaat ttttaatgtt agtaaaaact gttatataaa agctgaggca
     3841 ctaattagat tgagaaataa agagggcggt tattattctg cctatgaagt tattacttat
     3901 gcagaaaagc atggacttat taaggatgta ggtctatatg tactaaaaaa ggcttgtgat
     3961 gtaactacaa aaataaaaga taaaaatata gactttgaac aaatgcaatt aaatttatct
     4021 gctcagcaga ttgtacataa gcagtgtgca aatgacatat tatcatgtat tgagaattgt
     4081 ggtctagata aaaagtatat ttctgttgaa gttacagaaa aagtacttat ggaaactttt
     4141 gaaattgtaa atgttactct tgataaacta aaaaaagaag gcattagcat agctttagat
     4201 gagtttggtt ctggatttag tagtataaat tatctggcaa atttacctat tgaaaattta
     4261 aaaatagata aggaattagt agaacaaatt acctattcta aaaaacaatt tgaattatta
     4321 aaaactatag ttcaaattac taagattaat ggcatggata ttgtagcaga aggtgttgaa
     4381 acaaaagaaa ctctggattt agttgtaact tcaggtgtga atttgattca aggtcattat
     4441 ttttcagaac ctttaagtga agataaattt attgaactta tgattgaaga ataaaggtta
     4501 ataaaataaa gatttaaggt attgaaaaat aattaaaagt atttaataat agaattaggg
     4561 aagaataagt ttataagtaa aaacaattga ttagtagtta ataaaataaa tgtgatatcc
     4621 aaataaatcc taaatctaat ttgagtttta atatagatag tctaaagttt gattattaaa
     4681 gatttaattg taagttgtta cagttgatga tattgattag agattaaagt ttagagtaga
     4741 aagttacctt aaatttaaaa atgcaagata acccaatcta aaaattataa tcactcgata
     4801 ggtttaagga tttatttgtt tattataaat aggagggtgt ctcaaaatga actttttagt
     4861 ttatgaggca ctctctttta tatagaatta aatatatttt attatttcaa caatgaaaaa
     4921 gaagcttatc tctattttga gacagcctct ttgtatacta ttattaattt aatcaataac
     4981 ataatttaaa attataatac tagttaagat ttcctgcttt attagtaaat aattctttaa
     5041 tagcattgtt tctggaaact aaatcgttat cagagttgtt tgtttttttc ataatcactg
     5101 aataacgttt tttatttata aaaaatatta aaatcttatc atcatcaaaa ttgtattctt
     5161 tatatctgtc gatagactca taacctagat ttagaatgtt tttgtctttt atactatcta
     5221 catctaaaat atatgatggg tcagccttta gtaatatatt aattaaacat ttttcttcac
     5281 cagcacagaa taactccatc ttacttgata tagatttaga ttgctctgaa gttatttttg
     5341 caggaataag gttgtcatta tcatctctta gaagataacc atgtgtgtct tgttgatata
     5401 ctaaattaac ctttttctta ggaacactaa tcattttatc taaatgtaca taatgatgat
     5461 tttcaacaaa accttcattt aatatttcaa caaagttatt aattttacct aggcaaaaag
     5521 attctataga ttctttacag aatttatttg taaatggtat tatgtttacg ttttcctcgt
     5581 ctgtattcca tgctatagca taatccaacg aatatacttc ttcctctata tctgcaaaat
     5641 tatattgtac tatgtttcct ttcaaaatta ctcgacctcc atcttataat atatttaata
     5701 tactttataa aacttatatt atatttaaat aatatcataa attgaataaa tatgatatag
     5761 taaataagaa aaaatttgaa aaaaatcact ataaatgagt aataaatata aatagtgtat
     5821 actaatggga tggaaaatgt ccactattaa ctttattacc ccacatatat aagataaaat
     5881 tattaatata aaatataatc tatcgacaat gaatagactt ttaaataaac ttaatataaa
     5941 attaattaaa taagtgctta aaaacgattt actttaatga tagaatcata ttaaaggagg
     6001 ataattttat ggatataaag aataaaatta aatctatatt tttaccagaa aaaaatgact
     6061 atttagatga tgaagaattt gagtatgata tagaaaataa tgaagaagat ttaaaggaag
     6121 ataacaaagt acatttaaat gatttaagca gagtaaaata tgattacaga gagttaaaag
     6181 acatagaaaa ccaaacagaa gagatgtgtc tgctagcagt aaagcaggat ggtactataa
     6241 ttgagtttgt aaaggacaag acttataaag tatgtatgga agcagtaaaa cagacatata
     6301 aatctcttaa gtatataaca aatcaaaatg aggatatttg tatagaagca gtaaaacaga
     6361 actacagagc tttgtactac ataaataata agacagaaaa tgtactaatt gaggctataa
     6421 aaaatgcatc aacttatgat gtcatggaag tatttaaatt tgtggaagag caaacagaag
     6481 atgtatgtct agcatttata gaaagggcat ctaaaaatga tgttgcagag atattaaaag
     6541 gaataaaaga gcaaactcca gccatatgtt tagaagctgt aaaaaaagat ggaaaatctt
     6601 tagcttatgt aaaggaacaa agtaatagta tatgtttaga agctgtaaaa gaaaactaca
     6661 gtgcactatc ttgtgtaaaa gagcaaactg aagaaatatg tatagaagca gtaaaacaga
     6721 atgactttgc attgtattat gtaaatgaac agacagaaaa aatatgtatg gaagcagtaa
     6781 aaagaagtta tatggctcta cagtatgtaa ataagcaaac agaagagatt tgtttggaag
     6841 cagtaagaat tgatggaaga gcattacagt acgtaaaaga gcaaacagaa gaaatttgct
     6901 tggagtcagt tagacaaaat ggaaaagtac tgcaatatgt aaaaaaacag actgaaaata
     6961 tatgtataga agcagtaaga ggttcatttg aagaacttga aataaaagaa atattaagtt
     7021 atgtaaagat accaacagaa agaatatttg tagaagcagt aaagcaaaat ggaaaaattc
     7081 ttaaatatgt agaaaatcag acagaattaa tatgtttaga ggcagtaaga gaaaactata
     7141 atgctttagc ttatgtaaag gaacaaacag aaaagatttg tttagaagca gttaatcaaa
     7201 gttatgaagc gcttaaatat gtgaaagaac aaacagaaga agtttgtcta aaagcagtaa
     7261 aacaagatta tagaatgttg aaatatgtaa ataatcaaac agaaaaaata tgtttagaag
     7321 cagtaaagca aaattataga gctttagaat ttgttgataa tcaaacagaa aaagtttgtc
     7381 ttgaagcagt aaaacagaat agaaaagcac tacagtatgt aaaacaaaaa caaagttaaa
     7441 aggctaaaat atatagaaaa catatgcaaa taaataaaat ttgatatttt gtaataaata
     7501 aaatgggtat ctcaaaagga actttttagt ttgtgaggta ctctttttat atgaaatgaa
     7561 atatattttt agccttttaa caatggggaa aaggtttatt tctattttga cataggcttt
     7621 ttatgcatat aaagcttgat aaaattgttt tattataatt gttttgttat ataaataata
     7681 agaagaaaat tatataggtc tttttttgac cagttttaca tttttaacaa ctagttttgt
     7741 aaagtatatt gaattttctc aaaaaagaat gtactctata tatgtaaaat ttttttggag
     7801 gtaaaaatgt ttaaaagata tgctgaaaaa atgacatctg ttttaatttg taataatatg
     7861 atagataata atgaatctaa agtctattct tatggatttg aaatattaat agctttcata
     7921 gttaatataa ccaccatgct gtttataggt tttttatttg gtaaatttac atatgtatta
     7981 ttttttttaa tgtgttattg tccaataaga caattttcag gagggtatca tgcagacaat
     8041 tattttagat gcttattaac ctttattttt ataattttat ctacaatctt aattatagaa
     8101 aatataaata tagacttatt taaaaatatt attatgatta ttgcaagtgt tagttgggtt
     8161 ggaatttgtg ttctgtgccc aatagaacat aggagtaacc ctataagtga tagggaaaaa
     8221 ttggtttata agaaaactgc tatatttata tctacagtag tgttattgat aacaatttta
     8281 agtctttctt tgagtatatt tgtagattat ttcacatata gcgcatttgc catgttttgg
     8341 atttttgtga tgttagtatt aggtaagtta aaagctaaag tataagtaaa atatgtatga
     8401 gggagagtta agttatgaaa aagtttattg taagatttat gaagtttgct agctcattgg
     8461 cacttagcac tgctattttg tcagctaata gtacctgtcc ttggattatt catcagccta
     8521 aagtacccaa agaaatcagc aatctaaaga agacaaatta aatacaagca cttatttata
     8581 caaaattatc aggaaaaaag aaattattat attttaataa gattaaaaca atataaaatc
     8641 agatacaaaa tttattttat ttattttata ggagcctaat acctatttgg taatatatta
     8701 gtgcgccaat ttagggggat atagtgtatt taatgaaatg acttacggag agtaagtcat
     8761 ttttgtattg tatgtatttt atgtaaactt atgatataat gaagggtaaa gtttaattaa
     8821 aataataaaa aactttagta tagatagtaa tttaggaggt agggtatgag tatgatacat
     8881 aaattttcta tgaatggata taatatcgtt ttagatgtga atggtggagc tgttcatgtg
     8941 ttagatgatg ttgcatacga tttgttagat ttttataaag aaaaaagtaa agaagaaata
     9001 ttagagatat taaaatcaaa atatcaagaa gaaaaaataa atgaagcata tgaagaaata
     9061 ttaaatttgg aaaaagaggg tcttttatat acagaagata catatcaata tcatccaagc
     9121 tttgtacata gagagcctgt agtaaaagct ttatgtttaa atgtagctca tgattgtaac
     9181 ttaaaatgta aatactgttt tgcagctcaa ggtgattttg gaggagaaaa agaacttatg
     9241 agttttgaag ttggtaaggc agcaattgac tatttgattg ctaattcagg aagtagaaag
     9301 aacctagaga tagatttctt tggtggagag cctttgatga actttgaggt tgtaaaacaa
     9361 ctggttgact atggaagaag tgtagaaaaa gattataata aaaatataag atttacaata
     9421 actacaaatg gtgtactgct aaatgatgag attatagatt atataaatga aaatatgcat
     9481 aatgtagttt taagtttaga tggaagaaaa gaagttaatg ataatatgag accaacttta
     9541 aatgataaag gaagttatga tattacatta ccacgattta agaaacttgt ggaaaaaaga
     9601 gcaaaagata agtattatta tataagaggt acttttacaa gagataattt agatttttca
     9661 aaagatgtta tgcattttgc agatttagga tttaaattaa cctctgtaga gccagttgtt
     9721 ggagatgaga gtaatccata tgcacttaga gaagaagatt tacctaagat atttgaagag
     9781 tacgaaaaat ttgctgtaga gtatgcagat agacaattac aaggagatgg atttaaattt
     9841 ttccatttta tgatagacct aaatcaaggt ccatgtgtaa taaagagaat aactggatgt
     9901 ggagctggaa atgagtatct ttctgtaact ccaaatggag atatatatcc atgtcatcaa
     9961 tttgttggaa atgaagaatt taaaatggca aatatatttg atgaagaaat agtacttcca
    10021 gaaaatttaa aaaatatgtt tagagaagct catgtatata ctaaagaaga gtgtaaacaa
    10081 tgttggaata agttttactg ttcaggtgga tgtcatgcaa atgcgataaa ctttaataat
    10141 gacatatcaa aaccatatga attaggatgt gaaatgcaaa gaaaacgtac agagtgctct
    10201 ataatgatac aagctaagtt aatgttagaa ggagcaacca actaaattta tattttaaag
    10261 gagttgttta tatatgatta gagattattt agaagataaa cctttaattg acgaaagtgt
    10321 atttgtggca aaatcagcag atgtaattgg aaatgttaaa ataggcaaag attcaagtat
    10381 atggtacaat gcagtagtta ggggtgatga aggaccaata actattggag aaaacactaa
    10441 tatacaagat tgttctatag tgcatggaga tacagaaact ataattggta acaatgtaac
    10501 agttgggcat aggtctatag ttcatggttg taaaattagt gataatgtgt taattggtat
    10561 gggttcaata atattggata atgctgaaat aggagaatat actctgatag gagcaggtac
    10621 actaattaca tctaataaga agtttccacc aggtgttttg ataatgggtt ctcctggtaa
    10681 ggttgttaga gagcttacag aagaagataa aaaatatatt gatgaatctt atgaatggta
    10741 tttagaggca gcacaaaatc aaaaatatta gtttaaagag tggttgtttc aaaacatatt
    10801 taaatctgtt ttgaggcaac cactaattta ttttattaga ttttgttgat attttagttt
    10861 tcaaaaagta tttgattaaa ccagatataa aatgtcaaaa ataaaaatta actgagttaa
    10921 ataattttaa taaaattggt agtatatgtg ataaaattaa atattaaaga ggatatagga
    10981 tattagaata tcaattggtg aaataatgtc atatacgata aattaaggtg taagtttttg
    11041 ggtataccta tcttaggagt gaaaagattt gagaataagt tatagaaatt taaagcgata
    11101 tagagaaatt ggatatgttt taataaagta tggttttagt tttattgtag aaagactaaa
    11161 tatagaagga attgcctata aaataccact atttgaccca ccagaagaaa taaaaaatat
    11221 gacaactggt gagagaatga aaagagtttt agaagaacta ggacctacat atataaaaat
    11281 aggacagata ttgagtacaa gaaaagactt gttagaccag gatataattg atgaaatatc
    11341 aaaactcaga gatgatgtag agaaatttga ttcaaatata gctattgata tatttaaaga
    11401 agaagtgggt ttaagtatag aagaaatatt cttagaattt aaagaagaac caatagcagc
    11461 agcttcaatt ggtcaagttt atgaaggtgt acttaaaacg ggagaagaag taatcgtaaa
    11521 aattcaaaga ccaaatatag agaaaataat aaaatctgat ttagagattc ttagaactat
    11581 tgcaaatact ttaaaagatt taaaaaagga ttttaattta gatttagtac agatgattga
    11641 agaatttcaa actcaattaa tgagggaact tgattataca tttgaagcta taaatgcaac
    11701 taaattctct aggatattta aaaatagtga tgaagtatat atacctaaag tatattcaga
    11761 atataatact aagaaaattt tagtaatgga gaaagttaat ggtacaaagt taagtgatgt
    11821 agaaaaaata aggagactag gttataacac aaaaactatt gttgaaatag gagttaggtc
    11881 attttttaca caggtattat ctcatggatt ttttcatgca gacccacatc caggtaatat
    11941 attcgtagtt gctaaaaata agatagcata tatagatttt ggaatgattg gaattattga
    12001 taataaaact ttaaaccaat taaatgaaat tgcattagca ggtgtagaaa agaatgttga
    12061 caagataata tatctattga tagaaatgga tgcattaaat ggagaggctg atattaaggg
    12121 acttagacag gatttacttt atctaataca ttattactat gatatttcta tagaaaaaat
    12181 aaatgtaaca gatatattaa atgaactatt taggtttttt agacagtata aaatagtcat
    12241 gcctgcacaa tttgtaactc ttgcaaagac agttataaca ttagaaggaa caagtagaac
    12301 tttaaacaca gatttttctt ttggttctat gggaaaagag tttatgaaac atcattataa
    12361 gagtaaattt aaccctaaaa atgttgtttt aagttcaaga caaaatgtag aagaaatatt
    12421 actggacata aaaactattc caaagcaatt aaaagcaatt ttaaaaaata tagaaagaaa
    12481 taatataaaa atgcaaattg aagatgttaa aatgacgagg ttagaaaatt gtataataga
    12541 gctaacatct caaatatctt tgagtttagt gttggcatct attatagtag gttcttctct
    12601 tataattgca tctccaaata tagaaaataa tatatggata aaatttactg caatagcggg
    12661 tttctttata tcctttataa taggcctttg cttagttata agaagtatta ggtcaaaata
    12721 caaaaaagat tagggggaat taaatttgaa aaaatggata ttgaagtata aaggtaagat
    12781 agaggaaagt gaatttagca aaaaacttaa tatttccccg gaaatctgcc aaattttaaa
    12841 aaatagaggg atatgtactg aaaaagattc agaaatattt atgaatccat ctttagatta
    12901 tttaagagac ccttttttaa tgaaagatat gcaaaaagct gttgatagaa taaagttagc
    12961 agttgagaag aacgaaaaaa tttggattta cggagattat gatgttgatg gtgtatcatc
    13021 tacatctatc ttgtgcttat attttaagag tataggttac aatgttgatt actatattcc
    13081 taatagatta gaagaagggt atggtataaa tgaagatgct attaagctta taagctctag
    13141 gggatgtgac ttgattataa gtgttgactg tggaattaca tcagtgtctg aggtcaatac
    13201 agcgaatgat ttgggcatag atgttataat tacagaccat catgaatgtc aaagtgaaat
    13261 tccatcagcc tttgcagtaa taaatccaaa acaagaagat tgtaattatc catttgattc
    13321 actatgtgga tgtggtgtag catttaaaat gattcaagcc ttgactccaa aagaagaatt
    13381 taaaactagt atgtataatt atttggaaat agtaacacta gcaactattt gtgatattgt
    13441 tccacttata gatgaaaata gaataattgt aaaaaatggt ttaaaatcaa tgaaagaagg
    13501 caaaaatatt ggattaaggg agcttataaa agtttgtggt gtagaaagtg ataagatagg
    13561 ttcttctcat ataggttttg caataggtcc taggataaat gcttcaggtc gattgggata
    13621 ttcttactta ggagtagagc tatttactac tcaatcacaa gaagaggcag tagaaatagc
    13681 tagtatattg gaagaaaaaa ataatgaaag acagatgata gaagctaaga tgtatcatga
    13741 agctgaagaa atgctaaagt ctaatagcag atacaatgat gacaaggtgt tggttttagc
    13801 taaagagggt tggcaacatg gaataatagg aattgtagca tcaaagttaa ctgaaaaata
    13861 ctacaaacca acaattcttc taggtataga aaatggggag gctactggtt cagcgaggtc
    13921 aataaaagga tttaatatat ttgaagctct cataaagtgc aaagacttga tgactaagtt
    13981 tggtggtcat gaacaagcag cagggttatc cttggattca gacaatgtag aaattttagc
    14041 aaatgaaata aataaatttg cagattataa tttaactgaa gatgatatga tagagaatgt
    14101 aaatgttgag tttgaattac aagaaaatgt aataaattta aatcttgtag aagaattaca
    14161 taagttagaa ccctttggat taaataatcc taatcctaga tttatagtta gaaattatat
    14221 tttaaaagat ttgaaagtta taggtaagaa tcaacaacat ctgaaattaa gcatagaaaa
    14281 agagaaaagc tatgaatgta taggatttaa tatgagtcat ttaaaatcaa tgtataaagt
    14341 aggagacaag gtagatgtac tattccaatt agatgaaaat aactatatgg gaaataggaa
    14401 agtacaattt ttacttaaag atatacgatt ggctcgacct aaaagtgcaa gtaatgacaa
    14461 actttcattg aaattaatgt caaaaataat accaaaagat actcaaagcc tgtataatat
    14521 atctgtgtct gattttgaat tatttgatgg aaatacagat ataaatatat ttgattattt
    14581 tgaaaaagat acactaataa tatctaattc tataaatgga ttttatagag caatgtcaga
    14641 tatatcactt atagatttgg attttaacat aaattacaat attattgaag atgatagcaa
    14701 aaatactgat aaattagagc ttatattttc tcctaatatt gataaaatag acttaaaaag
    14761 atataataat attattcttt atgattattt atacaataaa ggcgaatatt cgtatatata
    14821 tgagaataaa agagaagaaa gtgaaattat aaaatattat aataaaacag acctattata
    14881 tttaaagaat gtagttagta atatagttcc atcaagagat gaatttataa caatttataa
    14941 acaagcactc ataaaaaaag aaattgattt ggatatggta aatataaggg aaacttttaa
    15001 tgtaattcca ttaaagtttt ttacgatatt aaatgtattt agagaattaa atttacttga
    15061 ctttaattta aattatgaaa aaaattctgt actcataaga atattgccaa aaccacagaa
    15121 aaaattagac ttaaatgaga gtttaatact caataatcta aaaaatttag aaaaacaata
    15181 caatagcagt tattaggagg cgtttcccat ggatttaaaa aactttataa ggaatattga
    15241 tgatttccca aagccaggca tagattttaa agatgtgaca actctattta aagatggaga
    15301 tgcatttaaa tatgcagtgg attctatagt tgaagaattg aaagataaag atgtagattt
    15361 agtaatagga ccagaagcaa gaggattttt gatgggtaca cctgtagcat atgctttagg
    15421 agtaggattt gttccaatta gaaaacctgg aaagttacca ggtgaagttg agagttatga
    15481 gtatggatta gagtatggta cagatacttt agagatacat aaggatgcaa ttaaaaaggg
    15541 tcaaaaagta gcaatagtag atgatttatt ggctactggt ggaactatgg aagccgctgc
    15601 caagcttgta gaaaaattag gtggagaagt agtttctatg caatttttga ttgagctaaa
    15661 attcttaaat gggagagaaa agttgtctaa ctatgatgtt aattctctta taaaatacta
    15721 gtacttttat aatagttggt ataacaccaa ctattttcat atatattaaa attttataca
    15781 aaataggtgg ttatatgcat gataaagaat tacaagaaat aattgaaaaa ataaaagttt
    15841 atgcacctaa tgcaaatttt gaaatggttg aaaaagccta taatcttgca aaaaaagcgc
    15901 atgaaggaca atatagaaaa tctggggaac catactttat tcatccatta gcagttgcaa
    15961 atattttaat agagatggaa ttagatattg aaactataac agcaggttta cttcatgatg
    16021 ttgtagaaga tacagaatat acctatgaag acataaaaaa agaatttggc aaagaagtag
    16081 cggatttggt tgatggagta actaaacttg gtcaaataaa atatcgttcg aaagaagaaa
    16141 ctcaatctga aaatttaaga aaaatgtttt tggcaatggc gaaggatata agggttatac
    16201 ttataaaact tgctgataga ttgcacaaca tgagaacatt aaaatacatg cctccagaaa
    16261 aagcaaagta taaagcaaaa gagacacttg aaatttatgg tggtatagct catagattag
    16321 gaatttccaa gataaagtgg gaactagaag acagagcatt aagatttatg gacccagaag
    16381 ggtattatga tttagttagt agagtatcaa tgaagagaag tcaaagagag gattatattc
    16441 aaggaattgt tgaacttctt aaagataagt ttaaagattt aagtatacca tgtgatgtat
    16501 atggtagacc aaagcatttt tacagtatat atagaaagat gcaaaaaaaa cataagactt
    16561 ttgaagagat ttttgattta acagcagtaa ggatattggt tgataatgta aaggattgct
    16621 atgcagtact tggtatagtt catacattat ggagacctat tccaggaaga tttaaagatt
    16681 atatagcaat gccaaaaccc aatatgtatc aatcattaca caccactgtt gtaggtcctg
    16741 atggagaacc tttagagata caaataagaa ctcatgagat gcataatata gctgaaaatg
    16801 gtatagcagc ccattggaaa tataaagaag gtatctctag caaagagtca aaggttgaag
    16861 aaaaacttca atggttgaga cagatgatgg agtgggaaaa agatttaaaa gacccacaag
    16921 agtttatgga tgcacttaaa gaagatgtat ttaatagtca agtttatgta tttacgccaa
    16981 aaggagacgt aattgaatta ccagcagaat caacacctat agattttgcc tatagagttc
    17041 atacaaatgt aggtaataaa tgtgtaggag ctaaaattga tggaagaata gttcctattg
    17101 attataagct tcaaaatggt aatattgtcg aggtacttac atcatctaat tctaatggac
    17161 caagtaggga ttggcttaat atagtgaaga ccccaaatgc aaaaagtaga attagacaat
    17221 ttttcaagaa ggaaagaaga gaagaaaatg ttgaccgtgg aaatacaata ttagaaagag
    17281 aatttaagaa gcatgatata ccacaaaaag accctcttgt tgaaaaatat atggcattag
    17341 ttgctaagaa atttaatcag ccaagtgttg aggacttaat tgccactgta ggttatggtg
    17401 gtataatgtc atctcaagtg gtatctaagg taaaagacct atatttaaaa gaggttaaaa
    17461 aagctaaaaa ggaacaacag atacaagaag aagatttaaa taaacacaat ataagtgaaa
    17521 cagaatacag taaaaagaga aagaaaaacg catcacaagg aattatagta aaagggcttg
    17581 acaatatctt agtaagattt gctaagtgtt gtaatcctct tccaggagat gaaattgtag
    17641 gatatattac taagggtagg ggagtagcca tacacagagc tgattgccca aatgcaaaca
    17701 ataatggtga tttcttccaa aatagattgg tggaggtttc atggagttca gcaggaaaag
    17761 gtaagtttga agcggaaatt caaataaaag ctattgacag aagaggaatt gttaatgaaa
    17821 taactcatat tgttgcaatg gataaactta gtttaaacgg aataaatgca agaaaaggta
    17881 aggatagtat tgtaagtata aacttacttg tagaggttaa tgacacagag gaattaaaaa
    17941 ttctaatgaa aaaattaaaa gcaattcctg gtgtagaaag tatttataga atgacaaatt
    18001 agagttaaaa taatagggag gaaactatga gagcagtagt gcaaagagta tcttcatcta
    18061 aagttacagt agatgaaaac actataggtc aaataaataa ggggttacta gtattgttag
    18121 gagtgactca tgatgataaa tcaagtgatg tagattatat gattgataaa atattgaatc
    18181 tgagaatttt tgaagatgaa aatgacaaga tgaatttatc tctaatggat ataggtggag
    18241 agcttttagt agtatctcaa tttactttat atggagattg cagaaaagga agaagacctg
    18301 gatttagtaa tgcagctaga ccagaacttg caaataacct ttatgaagaa tttgtaaaaa
    18361 aagcaaaaga taaaggtgtg acagttggta caggtcaatt tgcagctcat atgatggtag
    18421 agttaactaa tgatggtcca gtaacaatac tattagactc aagtaaatct ttttaagggg
    18481 gaaaacttta atgattataa aaaaatttgt agatagttat tttggagtaa atacttatgt
    18541 attaggtgat gaaaagacta aaaaatgtgc agttatagac ccaggtggaa gtttagtaga
    18601 gacattaagt tttgtaaaag aaaatgaatt aaatattgaa tatattatcc ttactcatgg
    18661 gcatggagac catataggat atgttaagga tattaaagaa aaaactggtg ctaaagtagt
    18721 tgcacatgtt gatgaaaaag aattattaaa tgacaaaaat aaaaatctaa gttatacaat
    18781 gagatgtgga gcgcaagagt ttgatgcaga tatctatgta aatgataaag acaagcttga
    18841 acttggtgaa ttaaaaatga ctttcttgca tactccagga catactcaag gatgtatgtg
    18901 tataagagtt gaagatgaaa tgttcacagg agatactttg tttgctggaa gtattggtag
    18961 aactgattta tatagtggag actttaacca aatggaaaaa tcacttaaga aattatgtaa
    19021 atatgaagat gctgttagag tatatcctgg acatggacca accagtactc taggggttga
    19081 aaagaagaca aatccttaca tgtaatttta tattagtatt taaaaaagta taaaatattt
    19141 aataactata ttagtgaggg ggttcttcta ctgttaaata gaaggagtta agttgatgtt
    19201 gtatgttttt ttaaaaggac atgattataa gtatgaagta gcagaactta taaaattgtt
    19261 tactagtgaa tttaagttta aagactctaa tgctaacaat aatatagagt caaagcattt
    19321 aataaataga ttgatttatg agaatggtgt attattctca agtactgaat actatgaaaa
    19381 tggaaactta aagtacgagt caatacagaa tatagaaaat atgaatcttg aatttttaga
    19441 tggatttgat agcagcaaaa cgattgaaga atttcttaat agcctagata gtgaaagtaa
    19501 gaggaacttt aaaaagctgt gtaaagaaaa tatcaaaaaa agcatgtttt tagtgcttaa
    19561 acaagtattt aattcttatg taccatgggg aattttgact ggtattagac cagtcaaaat
    19621 tgtccacaat ttaatggata aaaagctaga tgataatagc ataagaacca ttctaaaaga
    19681 taattatttt ataatagatg agaaaataga tttagctctt gaaatagcta aaagagagcg
    19741 attatttatg tatcctatag ataaaaataa aatttctctt tatgtaagta ttccattttg
    19801 tccaactaga tgtgtatatt gttcatttcc ttcaaattca ttaaaacaat ttggacattt
    19861 aaaaagagaa tatgtttata aattgattga agaaattaag gggtttgcca aagttattaa
    19921 ggatactaag aaagaagttg aaactctata tattggtggt ggaactccaa ctacacttga
    19981 tgaggaagaa ttggatttgc ttataaattc attgttcaat gaattagatt taagtaaaat
    20041 taaagaattt actgtagaag caggtagacc tgacactatt acagaacaaa aactaagagt
    20101 gttaaaaaaa cacaatgtta gtagaattag tataaatcct caaactatga atgatgatac
    20161 cttggtaaag attggaagag agcatagagt atctgattta gtagattgct ttaatatggc
    20221 tcgtagaatg ggatttgata atataaatat ggatataatt ttaggtctta tagatgaaga
    20281 cttaaatatg gtaaagaaca cattggagga gataaaaaaa ctttctcctg aaagccttac
    20341 agttcataca ttagccataa agagagcatc taacttaaat ataaatatgg ataggtataa
    20401 agaacatcta acacaatatg aagaaatggt aaaaatgata gatttatcaa tgaaatatgc
    20461 aaaagatatg ggattaaatc catattatat gtacagacaa aaacatatgt tgggaaattt
    20521 agaaaatata ggttatgcta aagaaggata tgagtgcatt tataatatac agattatgga
    20581 agaaaaacaa agtaactatg cattaggtgc aggtgctata tcgaaatttg tctatgtaga
    20641 tgaagataga attgaaagag tagaaaatgt aaaaaatgtt gaacaataca ttgaaagagt
    20701 agatgaaatg ataaaaagga agaaagaaga ggtatataaa aatgttgact aaagctccta
    20761 gaggaactaa agacataact ccaaaagagg cttacaaatg gcgttatgta gaaaataaat
    20821 ttagagaaat atgtgcttta tatggatatg aagaaatggt aacacctata tttgaacata
    20881 cagaactttt caagagaagt gttggagata ctacagatat agttcaaaaa gaaatgtatt
    20941 cttttaaaga taaaggtgat agagaaatta ccctaaagcc agaaggtaca gcaggtgtag
    21001 taagagcatt tatagaaaat aaattatatg cagatactca accaacaaaa ttattttatg
    21061 tgacaccttg ttttagatat gaaagaccac aagctggtag acaaagacaa tttcaccaat
    21121 ttggaataga agcacttgga agtgatactc cttcaatgga tgctgaaata atcgcactag
    21181 ctgttcaatt ttttaatgaa gttggattaa atgatttggt agtgagtata aattcagttg
    21241 gctgtccagt ttgtagaaaa gagtacaatg ctttattaaa agagtatctt gactcaaaag
    21301 ctgatatatt gtgtgatact tgcaatgaga gaagagaaaa aaatccaatg agggttatag
    21361 actgtaaaaa tcctacatgt aaagaaaata tcaaagatat accatttatt gcagaccatt
    21421 tgtgtgatga ttgtaaatct cactttgata aacttcaaga atacttaaag gaaatgaata
    21481 taaactttgt aattgataaa acaatagtta gaggcttaga ttactataga aaaactgctt
    21541 ttgaaattat atctaatgat ataggagctc aaagtactgt atgtggtgga ggaagatatg
    21601 atggtcttgt tgaacaatta ggaggaccaa aaggtataag tggaattggg tttggactag
    21661 gaattgaaag acttttactt acacttgaag gtaatggaat tgaaatagaa aaccctcaat
    21721 ctacggatat atttatagta actataggtg aagaagcaaa tacaagaagc tttaaattgt
    21781 taaaagactt gagacaaaat catataagtg cagataaaga ccatatagag agaagtgtta
    21841 aagcacaatt taaatattca gataaaataa attcaaaatt tacaatagta attggagatg
    21901 atgagcttaa aaatgacact gcgacattaa aaaatatgaa aacatcagag caaactactg
    21961 taaaattaag tacattagtt gaagaattaa agcaaaagct gtaaaataag aaagtatgat
    22021 gttttgtgta ttagataaat atatagcatt aaaattaaat aaaatggagg tagtatcttg
    22081 gaaactttaa agggtttaaa gagaactcac tactgtggag agttgagaga aaaaaacata
    22141 aatgaagaag tcgtacttat gggatgggta cagaaaaaaa gaaatttagg tggtcttgta
    22201 tttgttgatt taagagatac aagtggatta tgtcaaatag tttttgatac agatgtagat
    22261 aaagaagctt ttgaaaaagc tgaaaaatta ggggctgaat ttgtaatagc tgtaaaagga
    22321 aaagtatgcg aaagacaatc taaaaaccct aatatgctaa ctggtgatat agaaatattt
    22381 gcaactgaac ttagactttt aaacaagtca gaaactccgc ctatttatat aaaagatgat
    22441 gatgatgttt ctgaagcact aagattaaaa tatagatact tagatttaag aaaaccatct
    22501 atgcaaagaa atttaaaatt aagacataaa gtaatgaata ttacaagaaa ttacttatca
    22561 aacaatagat tttgcgaaat agaaacacca tttttaatag ctccaacacc agaaggagca
    22621 agagattatc tagtaccaag tagagttaat ccaggaaaat tttacgcatt accacaatca
    22681 ccacaattat ataaacaatt attgatggta agtggtatgg atagatattt ccaaatagtt
    22741 aaatgcttta gagatgaaga cttaagagca gatagacaac cagagtttac acaaatagac
    22801 tgcgaaatgt cttttgttga gcaagaagat gttatgagta tgattgaagg tttgcttgaa
    22861 gcgatattta aagaagtttt agatgtagaa ttggcacttc cacttcctaa gatgacttat
    22921 gcagaagcta tgtctaaata tggttcagat aaaccagata ctagatttgg atatgagtta
    22981 acagatatat ctgatgttgt ttgtaactgt ggatttaaag tgtttgctga tgctacacaa
    23041 ccaggaaaaa gtgttagagg tataaacgta aaaggcaaag ctgacgactt tactagaaaa
    23101 caaatatcat cactagaaga acatgctaag acatatagag caaaaggtct tgcttggatg
    23161 aaagtaggac aagaaggagt aacttctcca atagcaaaat tctttaatga agaagaaatg
    23221 aacgctatac ttacaagaat gaatgctgaa gtaggagatt tacttttatt tgtagctgat
    23281 aaaaactcaa tagtatttga tgctttagga caagttagac ttgaagtagc aaataggctt
    23341 aatctattgg ataaaaatgt atataactta ctatgggtaa ctgagttccc agtttttgaa
    23401 gaagatgaag aaacaggcac attctcagca atgcatcacc catttacatc acctatggat
    23461 gaagatttag acaagttaga agaaggtgat aagtcatctt taagagcgaa agcttatgat
    23521 attgtattga atggttatga aataggtgga ggaagtgtta gaatatcaaa ttctgatgtt
    23581 caatcaagaa tgtttaaagc acttggtttt acagaggaaa gagctaatga aaagtttggt
    23641 tatttattag aagcatttaa atatggtact cctcctcatg ctggtctagc ttttggtctt
    23701 gatagacttg ttatgttact tgcaggaact gataatataa gagaagttat tgcattccct
    23761 aaaaatcaaa atgctgtttg ccctatgaca aatgctccta cattggcgga agatgagcaa
    23821 ttagaagaat taagtataaa agttgatata aaagataatg aataatatgt agttgcaaga
    23881 aactaaaatg taaaaagtct ggatataaaa tatatttata ttcagacttt ttttattaga
    23941 attattttat attttttctc tatatatttt cataaattat acttatattc ttaaccaata
    24001 taattaaaat actatgttta aaaattttac ataaacttga ttattttaga aactacttct
    24061 gtaatgagta cacgatttta attaaagaat atataacaaa tttgaaataa gtctaatata
    24121 tgacttaata gattaaatta aaataataaa tttggactat ttatctattt ataacttaaa
    24181 ttatatcaaa ttgataacaa actagatatt atactttttt gtagaataga attacaatta
    24241 tataaagaaa aattctatta atagtgaaaa aaaagtagaa aaaagtagaa attattcttt
    24301 tataaagaaa gggagggata atattgcaag agagagaaga attagtttta aatccagttc
    24361 caaaagagga aagagttgga tggttagctc cattgtttaa tatgcttggt tctaacatag
    24421 ctatatctga actaatggtt ggaggaactt taattttagg aatgactctt tctaatatga
    24481 ttattacatc aattataggg aacttaatat tagttgcaat tattatgata caaggttata
    24541 taggttacaa agaagggtta aatacgtatg tattagctaa gggggcattt ggagagatag
    24601 gaggaaagta tcttatatct ctattacttg gtataactag ttttggatgg tttggtgtac
    24661 aagcaggggt tgcaggacta tcagtacaaa agatatttcc aagtgtaaat ctaacattag
    24721 ttacagttat acttggatta tttatggttg tttttgcact gtatggcttt aaagctatgg
    24781 ctaaatttaa ttacttagtt ataccaccac ttatgatatt aatggtgtgg ggagttttta
    24841 aagctttttc tacttatgga gttgaagcta tttataatta tactcctcaa acaactatga
    24901 gtatggttga aggtcttaat attgtagtag gtcttgttat agttggtgca attatatcac
    24961 ctgaccagtt aagatatacg agacgagtaa aagatatttg gattatcagt tttttaggtc
    25021 tagggattat ttcattattc caacaagttg cagctggtgt aatgtctatg ggagcaccta
    25081 cttgggatat aacagaagta ttggctaatt taggttttgg atgggtagcg tttgttattt
    25141 taatacttgc atcttggtct acaaacgtat caaatgctta ttctggtgga ttagcattaa
    25201 aaactatttt tccaaatgta aaaagaaatg ttttgacttt agttgcaggt ctaataggta
    25261 caataatagc agctactggt ataatattta aatttcagtc atttttatct ttcttgggaa
    25321 tcgcagttcc tgcaatagct ggaattatgt ggtgtgagta ttattttata caaggaagaa
    25381 cttataagca tagagaagga ataaattgga ttgcagtaat aagctggtta ataggttttg
    25441 cagcgtcgta ttatagttca aaaataaatt tcttaatacc tccgataaat ggaattgtag
    25501 tgagtatggt tatttattat atattaatga aatgttttgg aatcaaagat aaataaaggg
    25561 ggcaattaca tgggtcgtaa ggtgaaaata ggtataattc aacaacacag tgtacttgga
    25621 gatgttaaaa aaaatataga aaaggcagta gagatgatag atgacttagg aaaacaaggg
    25681 gcagatataa tttgtttacc agaactattt gctacaggat ataatttaga gtctttaggt
    25741 ggagttaaaa cattagaatt aataagagaa cataataagt acatagagga atcaatgtca
    25801 gaagctgcta aaagaaataa tgtatacctg atatctccat atggaacctt agaaaaaggg
    25861 tctacacatg tttataattc agcagttata tttgatagaa aaggtaagat tatgggagaa
    25921 tactgtaaaa atcatctgtg gtcattagaa gcagtatact ttaaaggagg ggaaaaagta
    25981 gaggtatatg atgctgattt tggtagattt ggtgtaatga tatgttatga tgcaggtttt
    26041 ccagaagtat ccagagaatt gacattaaaa ggttctgaaa taatatttat accatctgca
    26101 tggagaatac aagatgaaga tatgtgggat ttaaatgtat ctcaaagagc tttagagaac
    26161 actgtatata cagtaggtgt aaatttagta agtaatgact ctaatttaat actatttgga
    26221 aagagtaaaa tatgcaatcc tagaggtact gtaataactc aattagatac atacagggaa
    26281 aaatatgtat tatcagagat tgatttagat gaaataaaaa agtataggga agatatcccc
    26341 tatttgaaag acagaaaaag tagctataac atataattct atactataat acaagttcaa
    26401 tataaaatga taaaaagagg atgtatcaat attaagatta aatttattat actttgatat
    26461 atcctcttta atattatcaa ctttgattta aatattttta aaatagttga taagaaagtt
    26521 tttgaacaac aacacagctt tagattcata gttttcgcta aaccatgaaa gatttaaata
    26581 tcttttaaat tcaatatctt tgatatgtaa caacttaatc tcagggtctt gagataatcc
    26641 ccatgatttt ccacatataa atccaactcc ttgaagtgat tttataagag cataaattgt
    26701 atatggtgaa tcagactcaa atgctatttt gggtttgaaa ttagctgatt cgcacaggat
    26761 atcaattacc tctctataat tctcaccctt cgttataact ataaagtttt catctgaaac
    26821 ttcgcttaga tatacttcat cctttaatga taaaggatgg tttattgaaa ctcctaatag
    26881 tatttcttcg catgttaaag ttatgctatt ttctgagttt agctttgtaa atgaagaaga
    26941 tatgtacaaa tcaaaatcac tttttttata agatgatggc aaagtatgtg acacattaaa
    27001 agtaatattg ggatatagtt ttctgaaatt actcaaaagt gatggtaaca cattagccgc
    27061 tgcaggagat aatatcttta cttctcctga attttctaaa gaagtgtctt gtaactcctt
    27121 ttttgaactt tctactaaat ctaaaatgct atctactctt tttagaaaca atcttccata
    27181 ctcatttaaa acaatatatc ttccttttct gtcaaataac tgaactccaa gttctttttc
    27241 taaggaagat atagttttgc ttaaagctgg ctgtgctata tttaacttgt gtgatgcttt
    27301 tgttatgtgc tccattctag caacagtttg aaaatactta agatgcaata aatccatagt
    27361 ataaaataca cctcttttaa tatgacttga gttatatcaa ttttataatc aactccacat
    27421 tatacattat aatataaagt ttatataata aactacaata tattaaaaag ttatttaaat
    27481 tgttatttat attttgtaca taatctaatt aaaaaaagta actttaaatg attaactaag
    27541 gaaatgttgt tacaaacttt agttatataa aaaattcatt tgatgagcaa agtactaata
    27601 tcaagtaaga ataaaagctt attagataag aaaaataata ttttataata atgatgttac
    27661 ttaaattatt atgttatact attttaaata ggaaaaattt agatactata attttagggg
    27721 gagtcaagat gaaattaact aaatcaatat catcaatgct gtgcttatct ctagttttaa
    27781 gcttatcacc agtagcatat gcaaatgaaa taagtagaac aacagttgag aatactttag
    27841 taggtcagga tagatatcaa actgctgttg aagtaagtaa aaaaggatgg agtagtgcaa
    27901 atgaggctgt agttgtaaat agtgaatcta ttgtagatgc attagctgta acaccatttg
    27961 ctaaattaaa aaatgctcct atattattga cagaaaaaaa taatctaaat tcacaaactg
    28021 agaaagaatt aaaaagatta ggagttaaaa aagtttatat aattggtcta tctagttctg
    28081 tatcaaatga tgtgcaaaaa cagttagaat ctaataattt aactactgat agagttggtg
    28141 gtagtgatag ataccaaaca gctttgagta tagctaaaaa aatagaagga ttaaaagata
    28201 tatcagaaat agctgtagta aatgggtaca caggtcttgc agatgcagtt agtataggtt
    28261 ctgtagctgc tactaatgga atggttatac ttccagtatc tgatgcatct ggtatatcta
    28321 gctttaaaga ttttatagaa tctaagaata taaataaatc atacataata ggctctacta
    28381 atgctgtatc agataaaata aaacaaagtt tacctaattc agaaagaata ggtggagcag
    28441 atagaaatga aactaatggt aaagtaatag aaaagtttta tacatctaat aaattaaaca
    28501 atgtatttgt ggctaaggat ggaatgaaaa atcaaaatca acttatagac gctctagcag
    28561 taggagtact agcatcaaaa gaaaattctc ctgtactaat cgtaggagaa caattaagtg
    28621 caacacaaaa gagtgtattt tcgaataaaa atgctacctc tataactcaa gttggtagtg
    28681 gaggaaatga aaatgcattt aaagaattaa aagatttaca ggcaaatagt aacaataaga
    28741 gagtaatgta tgtaactaat acagataagg taaatataag aaatgatgct acaatagaag
    28801 cttctgttat aggatatcta aataatggtg atgaagtaga agttttagat gtgttaaaaa
    28861 ctggatgggt aaaaataaaa tacaatgaag gtattggata tgttagtggg tcttatttga
    28921 caaataataa gcctgataat agtaatgaaa atataaaaat aaagtatgta aaagaaaaag
    28981 atggtctaaa tgttaggaaa ggaccaagta cagaagatga aaaaataggt cacctttcat
    29041 atggaagcaa agtagaaaca atagaaatgt ttgctactgg atgggtaaaa ataaagtaca
    29101 atggtggata tggttatgta agtaatgatt acttatctga tacaccagtt atttaattat
    29161 aagtaacaat aaaaaaactg ctttaatttg taaagcagtt tttttataaa aatttaagtc
    29221 taataactat ttctattttg ataccttaat cctgggattt attattatgg atattatcaa
    29281 catacaaaca ctccaaatcc agtgtctaat tccaaactta gatattaata aattcagtcc
    29341 tgctatggta aataagcagt atttaattac aattaaaagt gtatttatag aaagccccct
    29401 catagaaagt atcctaaatc caataataga cattctaagt cctataaatg ccaataatat
    29461 acctgcaata tcctgaatta agtaatagta ttcaaatttc atattcaatc aactcttctc
    29521 tgagcagtat caaatatttc taactcttca atttcatcat ctgtgtatgt aagcatagta
    29581 aaaccagtta caccataaat aaatgaaatt ataggtgtaa tccaacttaa gaaacaatat
    29641 ggaataaatt ctagtggact tacaccaaga gtctgagcac agaaaacagc atttgaattc
    29701 catggtatta atggaccacc aagtgtagct gtatcttcta taattctaga tagattttgt
    29761 ggttttaatt taaattcttt gtatattgga gacattagag ttccgacaaa tacagaagtg
    29821 aacatcattg atgaactaaa tgcatttgca aagtagctta ctataaaagt agacccaacc
    29881 aatttagttc ttgattttcc tattttagtt ataagaggtt gaagcagtac ttctaagaat
    29941 ccagtttttt ggagaatacc agcaataacg aaaactacaa atactagtaa aacggtttca
    30001 gccatactca ttattccacc acgatttaat agtttgtcgg catagacaaa tccagtatct
    30061 atagtaaatc ctgatagcat gtaatttaaa acatcaccta ttttttctcc ttcttgaaat
    30121 actgctataa taagtcccat gatagctgaa cttagtatag atataatggg tggcttttgt
    30181 agcaataaaa gtaataataa aaatattatt ggaatcattg ctactaaacc aatatgaaag
    30241 tttgaattta atacatcctt gatttgattt atttgaacat agtctatagt attatttgaa
    30301 tacttaaatc caattactgt atacagaact atacatatta cgtatgcagg tcctgtggta
    30361 taaaacatat gcttcatatg tgtaattaca tctgtcttac aaactgctgc agctaagttt
    30421 gtagaatctg atagaggtga catcttatct ccaaagaaag caccagaaat gactgcacca
    30481 gctgttaaac caagaggaat acccatacta gtaccaatac tcatcattgc tataccagaa
    30541 gttccaagag tcccccaaga tgtaccagta gcaacagaag ttaatgaaca tacgattaat
    30601 gttgtaagca gaaaatattt aggggttatt attgttagtc cactatatac tactgttggt
    30661 attgtaccag cagctatcca agctgctatt agtacaccaa cagaaagtat aattaagttt
    30721 gattgaaagg catctttgcc aacttcaaat ccaaaagctt ctatttcatc attagtataa
    30781 ccaagtttca tggctgcagg aactactata agccatgaaa gtaaaaacat tgtagttata
    30841 gaagcattaa atacaactat accaactgat gttagagcta ttattgcaag cattactaac
    30901 aaggaatatc taaatgaagg tatttttctt tctgtattca ttttcatagt gcaaattctc
    30961 cttaaatatt tttagttaat tgcatttttt attcttataa gagcttcttc aagcatactt
    31021 cttggacaag ctaagtttat tctttgatac ccacttcctc caatgccaaa gctgtttcct
    31081 tgatttagag caactttacc tttttgtaca agtatacttt ctagttcctc atcacttaat
    31141 ccaagtgcac taaagtctac ccataataaa taagtacctt ctggttttct aactttaagt
    31201 tttggcatat tttcatttat atattttata gcaaaatcta tattagattc taaatattct
    31261 aaaaatgatt ctagccaaga ttcaccatta ttatatgaag cttcagttgc aactaagcta
    31321 aagcaattat ttctctttat atcaattctg gtaaaggcat catctaacaa tttatagtat
    31381 ttttcatcag gtagtattac atatgatgat tgaagaccag ctatattaaa agttttagtt
    31441 ggagccatac aagtaattgt atttttttca aattctttag aaatagatgc cataggaata
    31501 tgcttatgtt tttttaatat aatgtcacta tgtatttcat cagatatgat ttttacatta
    31561 tgcttaagac aaatatctcc tagttttttt aattcatctt ttgtccatac tctaccaact
    31621 ggattatgag gattacaaag tatgaataat tttacatctt taatcttgtt ttcaatgtct
    31681 tcataatcca ttatgtagtt tccattttct aatttttgta atgggcttat aattagttct
    31741 ctattgttat tttttacaac actattaaaa gggctgtaaa ctggttcttg tatcattatt
    31801 ttatcatttg cttttgtgag ttcatttatt aaaagactta tagctgggat aacacctgga
    31861 ctataaatta accactcact ttttattttc cagttatgtc tcctatctag ccagtttact
    31921 atagattcat tgtaagaatc tggtcttgtt gtgtagccat aaatctcttg ttctagtcta
    31981 ttttttaaag aatcaattat acaaggtgca gccttaaaat ccatgtcagc cacccacata
    32041 ggaagtaaat cattagttcc atactttttt tccatttctg accatttaga tgaaaaatta
    32101 ttgcttctat caacaatctc attaaaatta taattcattg taaatacctc cagtaatttt
    32161 aattttatgt taataatatt aagcaaacaa cgtgccaata ttgataataa aaaatattta
    32221 ttcacaagtt aatatttaat attaagtaat ttcagagcat agataagata aaaatattaa
    32281 ttatacttaa aactttgtgg aaaaggttat ttctaataaa tttttaaata tatgaaaatg
    32341 taattaaata ggttaaatag gtttaactgt ttaacttgtt agacctattt atatttttta
    32401 gaaactctac tccctttgat gttataattg aacctccacg accaacaagt atgtctacaa
    32461 gcccaaagtc ttgtagttct aaaagcatat ttctaatctg ttgttctgtc aaaaatctat
    32521 tttcctctaa agctatttta cataagcttt ttctacctat tctttctttt aaatcataag
    32581 ccttttttaa attatccaat ataaatatgt attcatctag tgacctttta aaattatagt
    32641 cgtatttcat gatgtttttg tctttgccaa tgttgaattg atactttttt atattattac
    32701 ttactttatt acaaacggtt ctactataat ttgaatctat agtatctaat atatattcag
    32761 gtaaatcaca tatttctata atatcttttt ccaagtaaca gaaatattct cctaagtttc
    32821 ttaattctct tacatttcct tcccatctat acattttaaa gatttctttt acttcctcac
    32881 ttagaataaa attacatgga atatcatatt ttaatgaacc aaaaatttca aatatatcag
    32941 caggtctttc cctaagtgga tgtattttaa ggggaagaac attcaaccta aaatataaat
    33001 ctcttctaaa catattttta gatacaagtt cttttaaatt tctattagta gctgcaatta
    33061 ttcttacatc aatgtcaatg acattattag aaccaatacg tcgtacttgt ttttcttgta
    33121 tgactctaag taatttagat tgagaattta aatccatttc tccaatttcg tctaaaaata
    33181 tagttccatt gttggctaat tcaaataaac caattttccc acctttttta gcaccagtaa
    33241 aagccccttc atcatagcca aataattcac tttgcagtag attttcttga aaagtactac
    33301 aatttactgc gacaaaagga ccatcttttc tcctagaagc actatgaatg gattgagcaa
    33361 ataattcttt accagtacca ctttcaccaa ttataaggat agatgaattt gattgagcca
    33421 ttttattagc aatttttttt gtattaatag tttgtatact agaacctaat atatcatcaa
    33481 atgtgtattt actgatatta ccagagttta ctagttgtgc tcttaattta gcttgctttt
    33541 tttctaattg agaaaacttt gtcatcttta gtataaatcc atcaaataca tttaattgta
    33601 tatgtttaat ctctaaattt atatcaatat gatttatttt aatcaatttc tcaaaaaatg
    33661 gagttttatt ggtcaatatg ctttgaaaat tgatgtcttt tatgcaatca ccaacaaatg
    33721 agtcaatcat ttcatttgca tttatagaca aaatttttct agccatatga ttatagaatt
    33781 gaattattcc atcgttattt gtgcatataa ttccatcatc aattatagat agtaacaaat
    33841 caaattgtct ttcaaactta tttgcatcta acaataactc acctgtacta taacttgtag
    33901 gaattatttt ttctacgtat ttttttatta ggtcatcttt tattagatgt tttaatttgg
    33961 tttttgtagc aatttcaaca atacaactta aatctattat tctgtatttt aaatctataa
    34021 cttcacaatt tttaaactta ggcaagattt tttcgccagg agttaggatt acagcatctg
    34081 tgggagtaaa ctcaatctct ggatagcagg gcaggatatt tatattgtct attcctaatc
    34141 tatgtattaa agaaattgtt tctattgcca tatctttact taagttatat acataaataa
    34201 ttttatcttt ttctaatttg gatatcatat caatactgtt cttttcaaat gtcaacttag
    34261 gaacaatgat ttgagcatca tagtgagata attttactat ttcatcatat tttaaataag
    34321 cagataggag tataagtttt tctttaaaaa actttaaatt tccttcttca aatgagtata
    34381 aatttatctt tagattatca cctaagaatt gtcttatttg attttcataa atttctccag
    34441 cgtctttttt taaacttaca atagctaatt ccatttgttt cattttaacc tctcatacaa
    34501 atttgactta ttttagatta cataataatt aaattagatt aaataatatt atttaattat
    34561 tattataaat ttattataga ctacacattg aagtaaaaga agtagctaaa attattcctt
    34621 ttatttttgt tttttgtatc tatttggtat aatagtatta gagcgtataa taatttaggc
    34681 aaaatttttt aaggaagact agaggagaat ataaaatgaa aaaatgtctt tactgtaata
    34741 gggatataaa gtcaccaaat aataaattag ctataaaata tgatgacaat atgaatatat
    34801 atccatgtcg tgcagaatgt aaggaaaaaa ttgaagaata tatagcaaaa aaacctacat
    34861 ataagtttat aaatatatta gaggttcttt taggtgtggg cggaatattc tgctttttga
    34921 gtaaatggac tattgcagcc caagttgtac ttggaattga tgcactggtt atatttttat
    34981 tcccattggc aggatttaag atgaatggaa agttaagtat ggaacaaact aagaatcaaa
    35041 gtaggtctat tgcaatatca attttggcat ttatagtaat aataactgta ttatatttta
    35101 aacaaattgg taagtagagc ataattgtat aagacatcat tagagtatga ggtgagttta
    35161 tggaagaaag aaaattagca ccaaacaatg agagggaagc tctcataaaa agattaaaaa
    35221 gaatagaagg tcaagttaag ggtatacaaa agatggtgga acaagaacgt tattgtgttg
    35281 atatattggt tcaaatatct gctataaggt ctgctataaa tagagtaggc acaattatct
    35341 tagagaatca tataaaagga tgtgtagcag aaagcattaa acatgatgat gctgataaaa
    35401 ctgaagagat gataaaagag cttatggata ctataaataa atttacaaaa taaggaggcg
    35461 gttagttatg aatcaacaag gatttattat ggaaattgtt gatgatagaa ctgcaaagtt
    35521 aaaaatgcaa agacattcag cttgtgctgc ttgtggaaaa tgtgctacta caaattcagc
    35581 agagtcaaaa gaaatattag tagaagtaga caacacaatt ggcgcaaaag ttggtgacca
    35641 tgtagaagtg agtatggata atatgaatgt attaaaagca gctgtaatgg cttatataat
    35701 acctcttata gcacttcttg taggaacaat agggacttat tatatattgg gggcaattgg
    35761 aatgacaact ggagttgaag ccataagtgg attagttgga atttgtctta caataatctg
    35821 ttatttatac ttaaagaaga atgacaaaaa atttagagac agtagagaat ttataccagt
    35881 aataacaaga atattaattg acctttaaga taattataat taaaaaatag caatgtgctt
    35941 cttaaataaa tactcaatac gtatttgtag agtttaagta cattgctatt tttatatttt
    36001 tattttgatt ttctgtaagg aataaagttt tttctgattt tcaaaagatt caatgttctt
    36061 acaaaagaag ttacaactaa tacaccaagt gctattgcag cacttagaaa tagcgcatct
    36121 gtaccttttg acatagccaa agaataattt ttctgaatca aagacaacat tgtattatat
    36181 agcccaattc ctggtattag aggaagaata cctggaatta cgaacacaat agctggttgc
    36241 tttagttttc ttgctaaagt ctcactgcac gctgagacca aagcagcagc gataaaacct
    36301 gcaaaaactg catttgtagt aaaattaaat aaataaacat atacaatcca accaattccg
    36361 ccagttactc cagctggaag aagtagatat agtggagcat taaagaaaac agcaaatcca
    36421 gcagttgcaa cacctgaaaa taaaaaatgc aaaatcatag acatatcagt cattagaaag
    36481 gacctcctat tctataccat gtatcaagga caaaaccaac tccagaagca attgcaataa
    36541 taatcatagc agcatcaaaa gcacgagaaa ttcctgatat taaattccct gatattaaat
    36601 ctctaatagc ttttataaaa gcaactcctg ggagtagtgg cattatagcg ccgactataa
    36661 gcattttagg gtcatctaaa atgcctattt caactagtag aactcctgaa agtgcaatta
    36721 aaaaagaaga tactaaacag gaaaatgcag atattgcact tatcttcatc gttttatcat
    36781 aagtaattgc agcaaagatt gctattataa acgtaagtat aaaatttaat acataattcc
    36841 ctccaagcaa acaagcaaaa caagcagatg caattcctgt acaagagtaa aataaccata
    36901 aaggataagg ttttacatct tggatttcat aaagacgtgc aatggcatta tcaatatcat
    36961 actctttgtc actaacaaat tctcgagaaa aactgtttaa taaagaaatc ttatttaagt
    37021 ttatacctct tgattgaatc gttttcataa acgaaaagcc atcaaatttc tcatctgaaa
    37081 taattattac tgtaggagtt gtaaaaatat ttacatgata aaaccctctt gacctgcata
    37141 ttctaaggac actgtcttca accctagatg tttcagctcc attttttatc atcagttccc
    37201 ctacaaatag agctagtttt agaatatttt tcttatattc aagttcctca ttttgattca
    37261 taaatacacc tccaaattaa aaaacgtaat attgaaatta tatcaaattt ttaagtaata
    37321 ttccttaata tctatacaaa tatattatct tttttttgtt tcaaaatagt cacatttaaa
    37381 ttatatccaa ttaaaagaat tagacaatat tatttattat attttaactt aaaaataaag
    37441 aaagtaacta tgttaaatat ggaaaaatgg caaaacactt gactattaat tggtaaagga
    37501 ctataataat aaattatcat attgataaaa acgaaaatta tgaaatgtct gtaaaaataa
    37561 aatttaaata ataactagga ggagtaatat gtttgagaac ttgaaaaaag cggaccctga
    37621 gatttatgaa agtatgaaaa gagagttaaa aagacaacaa agaaatattg aattaatagc
    37681 atctgaaaac atagtatcag ttccagtaat ggaaactatg ggaagtcatc ttacaaataa
    37741 gtatgcagaa ggttactcag gcaaaagata ttatggtgga tgtgaataca tagatgaagt
    37801 tgaaactctt gcaatagata gaatcaaaaa aatatttgga gcagaacatg ctaatgttca
    37861 acctcattct ggagcaaatg caaatattgg tgtatatttt gctatgttaa aaccaggtga
    37921 tgttgttatg ggaatgaatt tatctcaagg tggacattta actcatggtg ctccagttaa
    37981 tatttctggt caatattata aattttatga atatggtata gataaagaca gtggacttat
    38041 agattttgat gaagttagaa agatagcaca tgaagtaaaa cctaaaatga tagttgcagg
    38101 agcaagtgca tatcctagag aaatagattt taaaaagttt agagagatag ctgatgaggt
    38161 tggagcattg cttatggtag atatggctca tatagcaggt cttgtggctg ctggtcttca
    38221 ccaaaatcca tgtgaagtgg ctgattttgt tacaacaaca actcacaaaa ctttaagagg
    38281 acctcgtggg ggtgttattc tttgtaaaga aaaatatgct aaagacatag acaaagcaat
    38341 attccctggt attcaaggtg gacctcttga acatataatt gcttctaagg cagtttgctt
    38401 taaagaagct ttaagtgatg agtttaaaga atatcaggta caagttgcta aaaatgcaaa
    38461 agccttagct gaagaactta ttaaaagaga ttttaaattg atttctggag gtacagataa
    38521 tcatttaata ctattagatt tgactaataa aaatataact ggtaaagcag cagaaaagag
    38581 attggatgat gcttatataa cagctaataa aaatacaatt ccatttgacc caaatggtgc
    38641 tcttgttaca agtggaataa gacttggtac tccagctgta actactagag gtatgaaaga
    38701 agaagatatg gcaataatcg ctgaggctat agacctatgt ttaacttatg atgaagaatc
    38761 taaggctaga acattggttg ttggtttaac tgaaaaatat cctttatatg aagaatataa
    38821 tattatggat taattataaa gaacaactaa ataaaataca tttaaataat tacaatgatt
    38881 gtgtatgtat ttgaatatat ttagatataa aaaaggtgtc tcaaaatgaa ctttttagtt
    38941 tatgaggcac ttttttgtat ggaatcgaac atatttgtat tatttaaata ataaaaaata
    39001 tggttatctc tatttttaga tggtctcttt gtatttttta attaaaactt taagatttct
    39061 taagaattat actaggtttt tctaaagatt taaagtctat acttataagt atagtaatca
    39121 tatgaaaaga aaagctttaa cgaggaggga atcttatgaa ggtattaatt cttacaggaa
    39181 aatttggtat gggtcattac tcagcatcaa attctttaag tgaagatata aaagcaaaat
    39241 ttgataattc agaaataata attaaagata tatttgagta cattatgcct aactattcag
    39301 ataaaatgta caagactttt tctattcttg taaatcgggg aagtagtctt tataatttgt
    39361 tttataaatg tgctgaaaat ggaaagaaag atataaaatt tactttttca gattattttt
    39421 taaataaatt agatacatta cttcatgaag tacaaccaac agtagttatt tcaacttttc
    39481 cattttgttc tcaattagta tcaagatata aggaaaaata taactcaaat cttcctttaa
    39541 taacatgtat aactgatata agtagtcact cagaatggat tagtaaaaat acagactgtt
    39601 atttagtagc tagtaaatct actaaggaag aacttgtttt taaaggaata gatgaatcta
    39661 agattaaagt taatggtatt ccagtaaaaa aagaatttaa aagaatagaa catgtaaatc
    39721 attcaactaa aaaaaatatt cttataatgg gtggaggatt aggattactg cctaaatcag
    39781 aacaatttta caaagaatta aatagtttag aaggagtaaa aactactgta ataactggta
    39841 ataataaaaa aatgtactat aaactatatg gtagatatga aaatatagag gtagtaggtt
    39901 acaccaatga agtatataaa tatatgaaag attctgacct tattatttct aagccaggtg
    39961 gaataacact atttgaaaca atttattcag aacttccaat attggcattt aatccatttt
    40021 tacaacaaga gatagataat gctagtttta tattaaataa tgaaattggg agaatacttg
    40081 gtaaaaataa aaaatactat gtagatgaga taaaagattt aatttatgat gatgctactc
    40141 ttaaagaaat gagcagtaac atgaaagaat taaaaaaaca atttgataat aataccttag
    40201 agaatatttt attttcactt gatgaacaag gagcgtgtag agaatgtatg tagtaggttt
    40261 aattatcgtt gttgcattga tttttttagt ccattcaatt atacctacat actataataa
    40321 actattaaat aaagaggtat taaaaaatat ggctggagaa aatgaaattg cacttacatt
    40381 tgatgatggt ccagataaga gatatacaga aaaattacta gatgtgttaa aagaaaatga
    40441 tatacaagct atgttttttg tagtagcaaa gaatgctgaa aaagagcctg aaattataaa
    40501 aagaatgttg agagaaaatc atatagttgg tttacattca ttggaacaca gaaatgcatg
    40561 gctttatagt tatagttatg ttaaaaaaga ttttattgaa agtacaaata taatgaaaaa
    40621 tttaggtgta gatgtaaact actatcgtcc accatggggt catactaata tattttcaaa
    40681 ttcatttgtt aaaaaatata atctaaaaat gactttgtgg gatgtaatgg cagaagattg
    40741 ggagaaagat agtacagtag acattattat aaacaagtta atgagtagaa caaaagaaaa
    40801 ttctataatt tgtttacatg atgcaggtga aaattcaggt ggtgcagtag gtgcacctga
    40861 gcgtactatt gaagctttaa agatagctat tccaaaactt aaagccagtg gtttaaagtt
    40921 cgtaacacca gaaaggatgt agttatgata agtaaaactg aaaagaaaaa taaatgccta
    40981 ggtagtgtag cttttttagt tttactaatg ggcataacag gatattttgt ttttagaggg
    41041 cagtcagttg aatcattgat aaaatcatta aaaggtgcaa gccctatgtt tatactaatt
    41101 ggatttgcaa tgatgtttat atatgttgcc tgtgaaggta taaatatata cttaggtatg
    41161 aaagctttaa accaaaagac tactctttta aaatgtatgg gatatgcttt tattggattt
    41221 tattttagtt ctattacgcc ttcagcatca ggtggtcaac cagcacaagt ttattatatg
    41281 aaaaaagacg atataaatat atcatattct tcacttatac tattagtcat tgttgttatt
    41341 caccaagtag ttatactggc atatagtgga ataatgttca ttatggaacg tgagtttata
    41401 ttaaataatg taagtggtat gaacatttta ctaatatatg gtgtaataac aaatgttgct
    41461 cttgtcattg gagtaattgc aattatattt tcaaaaaaac ttgtaaacaa ttttataata
    41521 tcaataacaa atttattagg taagttaaga ataataaaag atgttgaaag ttcaagaaaa
    41581 gttataatat ctcaaattga agagtatgtt aaaggtgctc aatatataaa gcagaatcca
    41641 aaacttgtag tccaaatttt agtcataact attgtacaaa taacatctat gtttttagtt
    41701 cctttctttg tatacaaagc ttttcatcta tcaacatata ctgtatttga gatattagcg
    41761 atacaatcct tgcttaatat tgctgtttct tcattaccat tgccaggggc tgttggagct
    41821 tctgaaaata gttttatgac attatttaag atatttttcc ctggtcactt attagttccg
    41881 gcaatgttac ttagtagggg aataagtttt tatgcatttg tagctataag tggattgata
    41941 tgtatagtag tacatgtaaa atcttctgaa aaagtaaaag cagtgaaaaa agttgcttat
    42001 gtaagataat attatataga ttatttttat taatatgtca atttgtgtgt atattttaat
    42061 taagctttaa acatgtttac aggagtagaa actattaaaa cgtgtgacat tgctaagctt
    42121 ttgctaataa agtataatat tttatatagt ttgaaatatt taagaaatat agcaaaaaaa
    42181 ggagcttggt gatgaataaa gagattccaa aaaaaatttt agtagctgat gataatcctg
    42241 agattaggga aatcgtagaa atacttttaa ctggtgaagg ttatgaagtt attatggcaa
    42301 cgaatggaga agaagctgta aacttagtag atagtacgat tgatttgatt attttggatg
    42361 ttgtaatgcc tgtaaaaaca ggatttgttg catgtaatga aattagagaa aaaacgacag
    42421 caccaatatt atttttaact gcaaaaactc aagactctga taaagttatt ggattttcag
    42481 caggaggaga tgactattta tcaaagcctt tttcatattc tgaactaatt tcaagggtta
    42541 agtcgctact tagacgttat tatatatacc agggaaagga aaaggaaaga gagccaaata
    42601 tattaaaaac aaaagagtta tgtgtcaatt tagatactca agatgttaca ctaaatggag
    42661 aacctgtgtt tttgacaact atagaatata gtatattaat tcttatgttg aaaaatagaa
    42721 aaaaagtttt ttcgtctgaa aatttatatg aaactatttg ggatgagcag tatttttata
    42781 cagcaaataa tacaataatg gttcatatta gaaatttaag aaaaaagtta gaaaaagacc
    42841 aaaaaaatcc acaatatata aaaaccgcat ggggaaaggg gtattatatt gattaacaaa
    42901 attaagccat ctaagttggg agttatacta ttgatatatg tagtaatctc agctgcagtg
    42961 gctttcattt taaatatacc attttactct gctgttgaat ctatagtaaa agatgtatca
    43021 gaagggaaag tatattttaa aagagaagta aatcaactta tggataattt tcaaacttat
    43081 gtgaataaca atggtataag agcagatgat ggagatgata tagcaaaatg gaatagtgat
    43141 aattggtttg tttctatgaa gatatataaa ggaaataagg ttttttatga tacattatac
    43201 tatcctaatg aagtacctga taagagtgag gaaaatgagt tttatagcag tcccatggct
    43261 agaaactatg agatacaatt ttctgatatt aaagctaata tagttgtagt agctttattt
    43321 agatttagat ttcaaaattt tatagaagca atttctatta catttatggc acttacattt
    43381 attataacat ttttactgtt gtttagtaga aagataaagt acctaaggaa aatagaaatg
    43441 ggtataaaga tagtagagag tggcagttta aagtatagaa tcccagtaaa aggtaatgat
    43501 gaattatcat cacttgcatc tagtattaat gagatgagtc atacattgga gaatcaactt
    43561 ataaaagaaa gggagatgaa gaataaaaat aaagatatag taacttcgat atcacatgat
    43621 gttagaactc cattaacgtc agtaatttgt tatttagatt tgattaaaga ccataaatac
    43681 aatagtcctg agcaattgga acaatacata aaaaatgtaa ggtctaaagc atatcaaata
    43741 aaagatttaa cagatgacct ttttacgcat tttgttaatt ctggagagga agtttcaaaa
    43801 gggtatgaaa aaataaatgc taatgaattt atttttcaat tacttttaga tagttcatat
    43861 acattggagg agaaaggatt tcatataaca atagaaaatg aactttataa ccaatatcat
    43921 atttatgtag atgttacaca atttagaagg atatttgata atttatgttc taatataata
    43981 aaatatgcta ggaaagataa gcctatagta tttttaatta aagtagagga ttctaaatta
    44041 ctaattatac aaaaaaatag agtaagtaat ttttctaaga atgtagaaag ttttggaatt
    44101 ggtataaaga attgtgagaa aatagttgca tatcataatg gaagcataaa tgtaaattca
    44161 gatgataaag aatttgctat tgaaatatct attccagcaa aagaatcata aaaatttaaa
    44221 ttatatattg tgtaattgct attatatatt gtgtaattgc ttatgtaaaa ttctatgaag
    44281 caggaagcat gtgactttag ttatgggatg ttcaatattg tgtacctcta ggcaagtaac
    44341 aagtttactt acaagaccat ataatattat tatcttaaaa aaaggggaca taataatatg
    44401 gttttgacag gagcacatta tatttacatt ctatttatgg taattatatt aattactatg
    44461 attatgaaaa aggatacaat agtaccatgt atattaggtg ttttttttat gggattgttc
    44521 tttgaaaaaa acatctttgg tgctataaca gcagtgttta actcttttat tatatcttta
    44581 aatgagttgg gtccaattat cttgattata gctattatgg ttgcattatc taaagcccta
    44641 gaagccaata atgctataca gtatatggtg agaccatttt cgagagttat aaaaaattct
    44701 aatacagcat tttttgtaac tggatttgtt atgttagttc tttcttggtt tttctggcca
    44761 actccagctg ttgccttagt tggagctgta tttttacctg ttgctatgag agctgggcta
    44821 ccagcaattg gtgttgcagt agcattaaat ttatttggtc atggtcttgc cttatctaca
    44881 gactttgtta ttcaaggagc tccaagtata acagctggtg cagcaggtgt tgcagtatca
    44941 tatgttataa atgatggtat gattttgttt tgggtgatgg gaatcgtaac catatctatg
    45001 gcattttata cattaaaaag agatattaac aaaggaatgt ttagagaaga actaaaaggt
    45061 tttgaaagtg aagaagtaga agcgttcaat ggaaaatcta aaatagcaac tattttagta
    45121 gctttgggat ttcttgctga tataattgct atgtatgtat ttgacctaaa aggaggagat
    45181 gcatcagctc ttttgggtgg aacagcagta tttttaataa taattataaa tgttataaat
    45241 tttggcaaag atagtcttga aaatgtatgt gagaatataa ttgatggttt tgtgtttggg
    45301 ataaaaatat ttggagcaat tataccaata gcagcatttt tctatatggg tgaagttgca
    45361 ccattgacag gtgtatttgg aaaagtatta gcaccaggtt cacaaggttt attatcagat
    45421 ataggcatag ctctttctca aacaatacca cttaataaat ttgccgtatc aggtatagaa
    45481 actgtagtgg gagcaataac tgggcttgat ggttctggat tttctgggat ttcattagtt
    45541 ggttcacttg cctctgtatt tggaactgct ataaatgcaa gtgttggtgc attagctgca
    45601 ttaggacaaa tcagtggtat atgggtaggt ggaggctgtc tagttccttg gggtcttatt
    45661 tcagcagcgg caatttgtgg ggttagtcca atagaattgg caaagcgaaa ctttgtccca
    45721 gttataaccg gattggttgt aacaaccata gtagcaatgt ttattattta ataaatcgaa
    45781 taaatcttta attgtataaa ttaaaaatag atgtgtagct ataatttatt ataattgttt
    45841 tactaattct aagccataca tctattttta ttgatatttt tattagtatt ctttaataaa
    45901 gtaatatttt tcattatatt atacataaca tctaaatata acatctaaaa tactgttatc
    45961 tatatttaat atcttgccaa attttttgat gttttattgc cctgtcccac caacatatat
    46021 aagctatcac aagtttttac ctatactatc accaaacaaa aattctaatt ttaatttatt
    46081 attttataac ctatattata ttaactatat tagtttgtag actttagatg taattataaa
    46141 tattaatact ccaagagttc aaattcatat cctagttttc ttgcatttga tataaaatca
    46201 tttaaaattt ctgtactagt tttggaaact gcatgtagta acaagataga accatcatgt
    46261 agattatcca ttattttttg cgttgcttct tcatgtgatg gttgtttatc agtatcccag
    46321 tctctgtatg caaaactcca aaatacagtc ttgtatccta aatttttagt cattgccaag
    46381 cttttttctg agtattttcc cataggaggt ctaaaaaatt taaccatatc tttcccagtt
    46441 acatctttat ataacttttc aacatcatat aattcgtcat taaagttttt tagattgctt
    46501 gtttttgttg gcatagatgg atgggtttta ctatgatttc caactatatg tccctcagaa
    46561 accattcttt ttactaaatc tttattttct tttatatatg gagctgtaac aaaaaaaact
    46621 gctttaacct ggttttgttt tagagtgtcg agtatttttg tagtgtatcc attttcataa
    46681 ccttcatcaa atgtaagata tagtgttttt tgaccatctt ttgtaggtcc attgtatagg
    46741 gcatcatagt cagaaaattt aaattcaatg tccgtattta cttctggtgt tttatgctta
    46801 ttgtttggta tataaaacca atcaagagta gtgttatcta aagaagatac atctaattta
    46861 ttattatcat tattagtagt ggcttttgat ggtttatctg ttccgtctga aactattaca
    46921 ttggaagtat ctttaccact atctattttt tccttatctt cttgtaactg tgtttcctta
    46981 ttttgatttt cgttttgatt gttttgtgaa tttgaacatc caacaataaa aaaaatagaa
    47041 atagaaagta gtgttaaata atgcaatact tttctaaaca ttttgaagct cctttctaaa
    47101 ttaataataa ttgcatataa taataattat atgattaatt acaattgcat atagtattat
    47161 tataattgga aattactatt aataatagtt atatctttaa aaataaagtc acaatagtat
    47221 gacaaagggt gaataatcaa taaatttaaa aaaaaatgaa aaaaatagtt gaccatatta
    47281 tgagaagatg ttattataat aaatgtgctc aacaagaagt aacaaaataa caagcacaaa
    47341 gaagttaatt gaat
//
LOCUS       DAMJVG010000025        45836 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.025, whole genome shotgun sequence.
ACCESSION   DAMJVG010000025 DAMJVG010000000
VERSION     DAMJVG010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 45836)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45836)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45836
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.025"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            55..171
                     /gene="rrf"
                     /locus_tag="PC512_001506"
     rRNA            55..171
                     /gene="rrf"
                     /locus_tag="PC512_001506"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            179..253
                     /locus_tag="PC512_001507"
     tRNA            179..253
                     /locus_tag="PC512_001507"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:211..213,aa:Asn,seq:gtt)
     gene            259..344
                     /locus_tag="PC512_001508"
     tRNA            259..344
                     /locus_tag="PC512_001508"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:293..295,aa:Leu,seq:taa)
     gene            360..435
                     /locus_tag="PC512_001509"
     tRNA            360..435
                     /locus_tag="PC512_001509"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:393..395,aa:Met,seq:cat)
     gene            443..517
                     /locus_tag="PC512_001510"
     tRNA            443..517
                     /locus_tag="PC512_001510"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:476..478,aa:Glu,seq:ttc)
     gene            532..605
                     /locus_tag="PC512_001511"
     tRNA            532..605
                     /locus_tag="PC512_001511"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:564..566,aa:Gly,seq:tcc)
     gene            611..686
                     /locus_tag="PC512_001512"
     tRNA            611..686
                     /locus_tag="PC512_001512"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:644..646,aa:Val,seq:tac)
     gene            692..768
                     /locus_tag="PC512_001513"
     tRNA            692..768
                     /locus_tag="PC512_001513"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:726..728,aa:Asp,seq:gtc)
     gene            779..853
                     /locus_tag="PC512_001514"
     tRNA            779..853
                     /locus_tag="PC512_001514"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:811..813,aa:Gly,seq:gcc)
     gene            863..936
                     /locus_tag="PC512_001515"
     tRNA            863..936
                     /locus_tag="PC512_001515"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:897..899,aa:Arg,seq:tct)
     gene            1920..2759
                     /locus_tag="PC512_001516"
     CDS             1920..2759
                     /locus_tag="PC512_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HDF2441262.1"
                     /translation="MLDINSFLNGFFNIILRMSIYDLIDISIVAYIFYKIFMFIKDTR
                     AEQVFKGIIFLLLATQLSNTFKLHTVYWISLKALDYGVIAALIIFQPEFRAGLEHIGR
                     AKFNLFGKNVNTSEETLNRNIEEIVEALYSLSRQKIGALIIMERETRISDIINTGTII
                     DAEISRQLLINIFIPNTPLHDGAVVIRDSKVKAAACFLPLTESKDLSKDLGTRHRAGI
                     GVSEVSDCITLIVSEETGGVSIAKAGKLYRDISRERMMNILRSNLKTNTETRSFFKGG
                     IFK"
     gene            2756..3937
                     /locus_tag="PC512_001517"
     CDS             2756..3937
                     /locus_tag="PC512_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441263.1"
                     /translation="MINRLKNNTKIKIISFLSAIALWMYVMAVVDPEETKGFEDIPVS
                     ISNMSDLKDKNLVIYPDEKLTADVYIKGSLSKVQSVKKEDIHVYGTIEDPIQGQKEVY
                     LKANIPQGVTLEFKHDVLVVNLEKNIKEKRDIKVEVSGNSKRNINKIELSKEFVDVSG
                     PRTLVKEVKSVRANLDVGNETDDFSKKLQLIPLNSDGTKVEGVTLSSSFVTAKIELLK
                     EKIVPIRVSLNDNKDNDVLKNYKLSKEQVTIKGKKEDIDKISYIKTKPIDLADLANGE
                     EKEVSLEIPEGITLEDSSITIKLNDTKQLSAEFLYNAGDIELRNIPTNMDNPNVISDV
                     DIKVVVESTEDLSKLNKKDISLYIDLSQGPEEDSKYKIKYETTYQFKKINIEPNIVEV
                     E"
     gene            4241..5143
                     /gene="ptb"
                     /locus_tag="PC512_001518"
     CDS             4241..5143
                     /gene="ptb"
                     /locus_tag="PC512_001518"
                     /EC_number="2.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate butyryltransferase"
                     /protein_id="HDF2441264.1"
                     /translation="MRSFEEVIKFAKERGPKTISVACCQDKEVLMAVEMARKEKIANA
                     ILVGDIEKTKEIAKSIDMDIENYELIDIKDLAEASLKSVELVSQGKADMVMKGLVDTS
                     IILKAVLNKEVGLRTGNVLSHVAVFDVEGYDRLFFVTDAAMNLAPDTNTKKQIIENAC
                     TVAHSLDISEPKVAAICAKEKVNPKMKDTVEAKELEEMYERGEIKGCMVGGPFAIDNA
                     VSLEAAKHKGINHPVAGRADILLAPDIEGGNILYKALVFFSKSKNAGVIVGAKAPIIL
                     TSRADSEETKLNSIALGVLMAAKA"
     gene            5165..6244
                     /gene="buk"
                     /locus_tag="PC512_001519"
     CDS             5165..6244
                     /gene="buk"
                     /locus_tag="PC512_001519"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HDF2441265.1"
                     /translation="MSKIFKILTINPGSTSTKIAVFDNEDLVFEKTLRHSSEEIGKYE
                     KVSDQFEFRKQVIEEALKEGGVKTSELDAVVGRGGLLKPIKGGTYSVSAAMIEDLKVG
                     VLGEHASNLGGIIAKQIGEEVNVPSYIVDPVVVDELEDVARISGMPEISRASVVHALN
                     QKAIARRYAREINKKYEDINLIVAHMGGGVSVGAHKNGKIVDVANALDGEGPFSPERS
                     GGLPVGALVKMCFSGKYTQDEIKKKIKGNGGLVAYLNTNDAREVEERIEAGDEKAKLV
                     YEAMAYQISKEIGASAAVLKGDVKAILLTGGIAYSKMFTEMIADRVKFIADVKVYPGE
                     DEMIALAQGGLRVLTGEEEAQVYDN"
     gene            6234..6911
                     /locus_tag="PC512_001520"
     CDS             6234..6911
                     /locus_tag="PC512_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2441266.1"
                     /translation="MITNDKRIRIITGHYGSGKSEFAMNYVVKLRDMVSGKVAIADLD
                     VVNVYFRTREKKELMKSLGIQPIDSSINAPTLDLPAVSAEVMSPMVDHSYNSVIDLGG
                     DNVGARVIGRFSHLLKEGDYDMLFVINANREKTQTSEEVIQYIKEIEKSSKLKVTGLI
                     NNTHLIRFTTIDDVLRGQKVAKEVSEKCNIPIRYVACLENLVEQLPKDLEGEIFPIKL
                     YMREDWM"
     gene            6954..7169
                     /locus_tag="PC512_001521"
     CDS             6954..7169
                     /locus_tag="PC512_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF2441267.1"
                     /translation="MAKGKVSFNQERCKGCGLCVEACPVKIIQLDSNVINKKGYNPAT
                     VFEMEKCIGCASCATMCPDVVITVERD"
     gene            7198..8277
                     /locus_tag="PC512_001522"
     CDS             7198..8277
                     /locus_tag="PC512_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HDF2441268.1"
                     /translation="MAKILMKGNEAFGKAAIEAGCKYFFGYPITPQSELPEYLSRELP
                     KIGGAFVQAESEVSAINMVYGGAGAGARVMTSSSSPGVALKQEGITYAVGAEVPCVVL
                     NVMRGGPGLGSIQPSQADYFMSTRGGGNGDYRTPVFAPATVQEAVDMIMEAFDVADYY
                     RSPVMVVADGMIGQMMEPVEFRAPEKKRELPPKDWATVGTKGKRKPNVINSLYLEPEV
                     LEDHCWHLQEKFDAMEKNEVQYEMYKTEDAEFVFAAYGTTSRVVKSAIDILREEGIKA
                     GLIRPKVLWPFPFEAFNQIPNARNILTVEMSMGQMVEDVKMAVEGKLPVYFHGRPGGM
                     TPTPAEIVEKAKKIIAGELVAGGAR"
     gene            8277..9029
                     /locus_tag="PC512_001523"
     CDS             8277..9029
                     /locus_tag="PC512_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HDF2441269.1"
                     /translation="MAVVFKKTEGLQDTQTHYCPGCTHGIIHRLVGEVLEELGVLGDA
                     VGVVPVGCSVLGYKYFNCDTQEAAHGRAPAAATGIKRVHPENTVFTYQGDGDLASIGT
                     AEIVHAAARGEKITTIFVNNTTYGMTGGQMAPTTLVGQRATTAQSGRNAETQGYPIRV
                     SEMLATLTGAVFVERVAVDTPAHVRQAKKAIKKAFQVQQAGLGFGIVEVLSTCPTNWG
                     LAPNDALQWLRDNMIPYYPLGNFKNVEVEEVK"
     gene            9030..9587
                     /locus_tag="PC512_001524"
     CDS             9030..9587
                     /locus_tag="PC512_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HDF2441270.1"
                     /translation="MSTARVICAGFGGQGVMSMGQLLTYAGMLEGKEVSWLPSYGPEM
                     RGGTANCAVTVSNEPVGSPLITDDATAAILLNIPAFEKFKDDVIPGGKIIVNSSLIKE
                     KVDRTDVDVYYIPANELAAELGNDKVANMIMLGAYLKVSDTVDIESVLEAFKKVFGPR
                     KEKFVPLNREALQKGMDATCSKATN"
     gene            9757..11103
                     /locus_tag="PC512_001525"
     CDS             9757..11103
                     /locus_tag="PC512_001525"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HDF2441271.1"
                     /translation="MRKYFGTDGVRGVANTELTCDLAYKLGRAGGFVLAQGDHRVKVV
                     VGKDTRISGDMLEASLIAGLMSVGCDVITVGIIPTPAVAYLTRKYGADCGVVISASHN
                     PVEYNGIKFFNKNGYKLDDEIELKIEEYIDDIDKIDCLPIGENVGRKLHEHCAQRDYV
                     DYLKSIISTDFKGLKVVLDCANGASYKVAPIVFDELGASVISINSSPDGNNINYKCGS
                     THPEQLQRAVLEHNADLGLAYDGDADRLIAVNEKGQIVDGDHIMILSALNLKKNNKLA
                     QDTLVVTVMSNIGLTIAAKENGINLSTTAVGDRYVLEDMVKNGYNLGGEQSGHMIFLD
                     YNTTGDGVLSSLILANIILQEKKPLSEIASIMSQYPQVLVNATIKNENKNKYMEYPEI
                     KTEIERIESILDGNGRVLIRPSGTEPLVRVMLEGKEEGQIKELATNLANLIQEKLS"
     gene            11370..13202
                     /gene="glmS"
                     /locus_tag="PC512_001526"
     CDS             11370..13202
                     /gene="glmS"
                     /locus_tag="PC512_001526"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003401499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HDF2441272.1"
                     /translation="MCGIVGYLGSRKAAEVIVEGLSKLEYRGYDSAGVAVNSSNEKEL
                     NIRKFKGRLSVLAEDLEKNPIDGNLGIGHTRWATHGEPSDVNSHPHFNQAKTIAVVHN
                     GIIENYMEIKEELISEGVKFESQTDTEVIAHLVDKYYEGNLLDAVYKTISKLRGAYAL
                     GVICKEHGNELVAVRKDSPLVVGVGEGENFIASDIPALLKYTRDVYFLENGEVVHLKD
                     ENVTVYDSNRNLVEKEVFHVTWDVEAASKGGYDYFMSKEIHEQPTGVRETLERRLDDN
                     GNIILDSINISKEDLEKINKVYIVACGTAYNAGLLGKYAIEKFVNIPVITDIASEFRY
                     SDPFVDENSLVILVSQSGETADTLAVLRDSKAKGARILSITNVVGSSIARESDDVFYT
                     WAGPEVAVASTKAYTTQITSLYMIALDFAIKKGTITREFYDSMISKMKEIPSKIQEIL
                     DNEEYIKEVAKTVVSSEHAFYLGRGIDYSLAMEGSLKLKEISYIHAEAFAAGELKHGT
                     IALIEKGTPVIAIATQEKLFEKMVSNMEEVRARGAYVVAIAQSHNKDVEKAADKIIYI
                     PNSDDILSPILAVVPMQLLAYHVSVLRGCDVDKPRNLAKSVTVE"
     gene            13653..14948
                     /locus_tag="PC512_001527"
     CDS             13653..14948
                     /locus_tag="PC512_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate sulfurtransferase"
                     /protein_id="HDF2441273.1"
                     /translation="MTNDFKKEKKEDYFVNLKAISTEVLQEKVQDNAWVIVDTRLNDA
                     YNGWKLDGVKRGGHIKGAVDFSANWLSVYSDRKDEVLEQALKTKRIDLDKNIVLYDAN
                     GKDALVVADYLSKKGYKYLYKYDIKQWADNENLPMERYKNYQMIVPAFIIKDILDGKI
                     PETFEDSKNIKMIEASWGEESYTKGHIPTSVHVNTDIIEPPPTWMLDNDDNLIKFALD
                     YGLTKDDTVIVSSSTPMASYRLAVILRYIGVKDVRVLNGGTNSWLSAGYELEFTSNPK
                     HSCTNFGADIPVNSQLVVTTSELRQKLKEKNKFILVDNRTWDEHIGKVSGYTYYDKKG
                     RIPGALYGHSGSDSVSLEEYRNIDNTMRNKYEILEMWDKENIDVNRQLIFMCGSGWRA
                     AEVLTYANVIGVENTSLYSDGWMGWSLDNSNLIEVGEHK"
     gene            15398..16135
                     /locus_tag="PC512_001528"
     CDS             15398..16135
                     /locus_tag="PC512_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YwmB family TATA-box binding protein"
                     /protein_id="HDF2441274.1"
                     /translation="MKRVKLAISFFILMIIGMTISYADTSINTKYNRLSKALEISEAN
                     FKFYNVKINSVINHNLSNKEFHNIFIEIINNLKLDKKGINWNQKGSGDKIQLCATIKG
                     SDKEISIKGINKNNKESYIVVDILDNKVYKHKEVIYSNVENVLNKYSSQVDVSACIVG
                     EYTKRLQNNKYDDILQKILYNMSAKQIDEVKDVNFLSITAYSKVLNDYELEYLGEKIN
                     LNIGIKYNEDDGRTLIYIATPIIKLDY"
     gene            16156..17409
                     /gene="murA"
                     /locus_tag="PC512_001529"
     CDS             16156..17409
                     /gene="murA"
                     /locus_tag="PC512_001529"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HDF2441275.1"
                     /translation="MAKIIVKKSNPLKGSVKIDGAKNAVLPIIAATLLANGKSTLNGV
                     PNLRDVHVISDLLRHVGAEVEYKENTLTVDASNIKTCEAPYELVRKMRASFLVMGPLL
                     ARFNSTKISMPGGCAIGTRPIDLHLKGFKALGAKIEMDHGFVEAATEKLVGNKLYLDF
                     PSVGATENIMMAASLAEGTTIIENAAEEPEIVDLANFLNEMGADVKGAGTNTIKIKGV
                     KELKGAEHNVIPDRIEAATYMVAAAMTKGDITVENVLMEHLKPVVAKLREAGCEITEM
                     DNSVRVVGPKVLKPIDIKTLPHPGFPTDVQAQFMAMLTVANGTGVVIETVFENRFMHV
                     AEFNRMGANIKIDGRSAVVNGVDELHGAAVNATDLRAGAALILCGLIAEGETQIGEIY
                     HIQRGYVDIDKKITALGGQIEIVED"
     gene            17496..18560
                     /gene="spoIID"
                     /locus_tag="PC512_001530"
     CDS             17496..18560
                     /gene="spoIID"
                     /locus_tag="PC512_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein D"
                     /protein_id="HDF2441276.1"
                     /translation="MKNPLVVLLGFVTCSVLVPSLITLVSYKNVELTEKAESPVSINK
                     TIKKSDIEDKGNKEEKNTVNYETVNKKAPIINVYNHITGKTEKMDMENYLCGVLAGEM
                     SSEFDIEALKAQSVAARTYVVYKQEHGKSSKHKNAVVCTDYKHCQEYKSYDTLKKLNG
                     EEWIKNKYSKIQEAVRGTKGQIITYNDKAILPLYFSTSSGKTENSEEVFSAKYPYLKS
                     VESPYDKYSPKFASTLKISNTDFVKSLRRAYSTIVIDVNNLSKQVSITKRSDAGTVEK
                     IKLGNKELTGKDIRTVFKLNSANFDIKFGEGYIDFVVKGYGHGVGMSQWGAEGMAEEG
                     YKYYDILSHYYTDTKIKDIY"
     gene            18626..19294
                     /locus_tag="PC512_001531"
     CDS             18626..19294
                     /locus_tag="PC512_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M23 family metallopeptidase"
                     /protein_id="HDF2441277.1"
                     /translation="MKKKLLEKDGFYLSLFVCVCLLAVGGVWFTNNNVDKLASNKGIM
                     ENANKDSEEEIHLIEKDKKDAIPTATDSKQNLEKAKSKEENKSSTTKLNYIGDKVIRG
                     YSEKEPSYSKTLDVWETHKGVDISCTKGKEVKSLLNGIVVDVFNDEEYGQSVKIKSDN
                     NIVVVYSNLDKNVSVKKEQKVTEGQSLGTVGSTSQIESEEGIHVHLEAYSGEKSIDPM
                     SLIK"
     gene            19392..19652
                     /gene="spoIIID"
                     /locus_tag="PC512_001532"
     CDS             19392..19652
                     /gene="spoIIID"
                     /locus_tag="PC512_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation transcriptional regulator SpoIIID"
                     /protein_id="HDF2441278.1"
                     /translation="MRSHIEERAIVVAKYILEKNTTVRQTAKTFGVSKSTIHKDVTER
                     LKEINPSLAKEVKNVLDKNKSERHIRGGLATKLKYEKEHKKM"
     gene            19849..20868
                     /locus_tag="PC512_001533"
     CDS             19849..20868
                     /locus_tag="PC512_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein"
                     /protein_id="HDF2441279.1"
                     /translation="MAGADIGIDLGTANVLVYVSGKGIVLEEPSVVAIDNRTDSVLAV
                     GEEAKKMIGRTPGNIVAIRPLRDGVISDYDVTEKMLKSFIDKIVDKKGFGRFFMPRIM
                     VCVPTGVTEVEKRAVEDATRQAGAREVYIIEEPIAAAIGAGVDISQPNGNMIIDIGGG
                     TVDIAVISLGGAVVSESIKVGGDRFDDAIVKYMKKQHNLLIGERTAEKIKFEIGSAFK
                     REEEKYMKITGRNLITGLPSSITINSTEMLEALRECVEQIVVATHAVLEKTPPELAAD
                     IGDVGIIMTGGGSLLYGLDKIIEQRTGITVTIADEPLSCVAKGTGIALGSIDLLETGG
                     SFKRK"
     gene            20884..21312
                     /gene="fabZ"
                     /locus_tag="PC512_001534"
     CDS             20884..21312
                     /gene="fabZ"
                     /locus_tag="PC512_001534"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HDF2441280.1"
                     /translation="MLNIDEIKKLIPHRYPFLLVDKITELEVGKRAVGIKNVTVNEPF
                     FQGHFPEYPLMPGVLIVEALAQVCGVAMMSVEENKGKLGVFAGIDKVRIKREVRPGDT
                     LTMEVEMTTLRRNIAKADAKAYVGEELVCKGELMFALVEK"
     gene            complement(21423..21932)
                     /gene="yyaC"
                     /locus_tag="PC512_001535"
     CDS             complement(21423..21932)
                     /gene="yyaC"
                     /locus_tag="PC512_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore protease YyaC"
                     /protein_id="HDF2441281.1"
                     /translation="MYLAKVNYSDDDVIQMLSSVLKTIINENTIVVCIGTDRAIGDTL
                     GPLVGTILKNSNFKYPVYGTLDNPIHALNIYESLDTIKNTHIQGNFLAIDACLGSQSN
                     IGNIQIREGPILPGKGVGKKLPQIGNYSIVGIVDKIDENNKLSFNNIRLSFILDLAET
                     IALALLVST"
     regulatory      22121..22224
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            22360..23553
                     /locus_tag="PC512_001536"
     CDS             22360..23553
                     /locus_tag="PC512_001536"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HDF2441282.1"
                     /translation="MARHLFTSESVTEGHPDKICDQISDSILDALLEKDPQSRVACET
                     TVTTGLVLVAGEISTSAYVDIPKLVRETVREIGYTRAKYGFDCDTCAVITSIDEQSGD
                     IAMGVDEGLESKTGEEIEEEIEKVGAGDQGIMFGFACNETPELMPLPISLAHKLSRRL
                     TEVRKTGLVDYLRPDGKTQVTVEYEGSKAVRVHTVLISAQHCETVSNDKIREDLINHV
                     IKEVIPAELLDEDTKIYINPTGRFVIGGPQGDTGLTGRKIIIDTYGGYSRHGGGAFSG
                     KDPTKVDRSAAYAARYVAKNIVAAGLADKCEIELAYAIGIARPLSIFIDTFGTGKVSE
                     EKLVELVNKHFDLRPGAIIRDLDLRKPLYKKVAAYGHFGRTDIDLPWERTDKVEQLRK
                     DALGE"
     gene            23868..24965
                     /locus_tag="PC512_001537"
     CDS             23868..24965
                     /locus_tag="PC512_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441283.1"
                     /translation="MSGKVNIKTVISFAGAYVATVIGSGFATGQEILQFFTFYGYAGI
                     IGGIISMVLFSWFGAEVIDKGRELKLKEPIKIYQVYCGKYLGTFFEWFGPLFLFGTLV
                     IMIAGAGATLSEYYGLNPYVGRIGMTIVSLITVSLGLTRLSKILGNIGPIIIIFTLLV
                     GAISLFSNIDALSNAGNMVDSLNIKTATSNGYFSGVLYTCYNVIIVITFLTGMGASAV
                     NKKDAVWGGIVGGVALMAAAIMMNLALLSDIGNIYTKEIPALYLADKISPIIGILFSV
                     VLLLGIYTTAVPLLWSVTNRFVEDDHPKFKIITIVVSILACIGGLLPFDKLVGTLYPY
                     TGYMGILILLCMLYRRITKTEGYKENKSEIS"
     gene            25229..27448
                     /locus_tag="PC512_001538"
     CDS             25229..27448
                     /locus_tag="PC512_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HDF2441284.1"
                     /translation="MEKLEGMISEIVFKNEDNGYTIAHLVNENDEIVVVGCMPTLAIG
                     ESIEVEGKWVNHKIYGTQFEVNSFMPVTPSSLEGIYVYLSSGMIHGIGEKMAKRIIDK
                     FGVDTLEVIQNSPEKLQEVEGIGSKKVKQIVKSYEEDRELRNIIIQLSPFGITPNYCL
                     KIYKKYKSSAIEVINKNPYQLAEDIRGIGFKVADSIANKIGIDKNSKDRICQGILYTL
                     NKSLSNGHTYLPEHVLIQDSEKLLELNGEIIKECVMMLVYNQKIHVEKVNNENLIYLM
                     PYYLAENGVCSQIVKLSQYEFEDLKIDIDNEINVLEEDKKIKLAEKQILAVKESVNSG
                     VLIITGGPGTGKTTTINAIIDIFENNGKSVTLAAPTGRAAKRMSETSNKEAKTIHRLL
                     EMGFSTDDDLTFFKDEEDPINSDVIIVDEVSMVDIILMYNLLRAIKLGTRVILVGDSD
                     QLPSVGAGNVLKDMINSNIINVVKLNEIFRQAQESMIIVNAHKINNGEPLYLNTKGKD
                     FFFIRKSTNEEILNEIIGLVNERLPKFYKVDKLKDIQVLSSMRKGELGVTNLNIELQK
                     YLNKKEKFKVEESFSKRLFRVGDKVMQVKNNYTKKWETEDQKESGEGIYNGDIGYVYH
                     IDKDKKTIYILFDQTKIVSYLYDELDEIDHSFCTTIHKSQGSEFPVVVLPIAWAPPML
                     LSRNLLYTAVTRAKKLVVLVGDVKYLEYMIKNNRVNQRYSNLGYKLNKFKQEGLLIE"
     gene            27451..28233
                     /locus_tag="PC512_001539"
     CDS             27451..28233
                     /locus_tag="PC512_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HDF2441285.1"
                     /translation="MKICNDNFIKNFKNMINKCLDFIYPENISCIICDKSIKKTNTYS
                     ICKSCFKEMNFIQDGCMKCGKPIIRHSIEKEFIEECSYCFNKDFYFDKSISCIEYNDV
                     TKKIVLGLKYNQKTFMAKYIAQIMKEKLYLENIKFDYILFVPLHKKRLNKRGFNQAQK
                     IAFNLSKIVNIPLLDCISRKKYTRMLYKLNKKERKEELKNVFVVKDNVKLINNKNILL
                     IDDIFTTGLTTNEISKLLKLSGANKVFVLTLLTKANDNYIME"
     gene            28565..30478
                     /locus_tag="PC512_001540"
     CDS             28565..30478
                     /locus_tag="PC512_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF2441286.1"
                     /translation="MICLNKRQENLLTTLLLKEEFINVNKIANDFECSERTIRNDCKY
                     IDEWLSTFCNAYIKRKPNIGIKFSGDGTDKILVNQKLRGEVKRVNSELHKQVEILNLL
                     LCNNKKVTLNDLSNKLYINKNIVREEISKLSVALNNYNLNVSTKKGSGIYIGGDEKDI
                     RIMLVSFLFKYIDKYRLNIDEIEYFHIVDIIIVKNIMFTIEEDMDIRLTDISFKQLML
                     FLLINIIRIRLGNSLKVSNTKKELKLKMLILDIEDELKSNLSIVLNYEEKLFIESLIL
                     GMNKQINSSNIKKSLYLNEELASYTKKIINLVSEESGINFNNDILLYEQLICHLNVTM
                     HQMKSNVYLENPLLDNIKTKFCFLFTVISSSIEIELKGKQITEDEIGYLTLHFQTSLE
                     RKYSKRESNKKASIVCPFSFGVSMLLKVKIEKRFDNIKIIETLREEDLKRDNFNKTID
                     FIIAFQEYENIQKPIFITTPLFTDEDENKLKEFTNKIKEKDTSYKLMNRLMMSDYLIR
                     ELEHDDIYEAITYLTNLLIEKHYAEKEYLQSIITREKSYPTNVGKGILFPHGDMKYIK
                     QSVLCFARLKTPIRIRNGKDIKIILLLAYKKDDDRKVFRELFKEISNLTEDENMLDIL
                     SKCDIEKVKDILI"
     gene            30619..30927
                     /locus_tag="PC512_001541"
     CDS             30619..30927
                     /locus_tag="PC512_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDF2441287.1"
                     /translation="MEEIVLKIIIHAGNAKSMLYEALDYAKENDFKKADELIENANEE
                     ILKAHKVQTELIQKEAGGDKSDISILLIHSQDHLMTCMSERNLIKEMIMLRKEIQKLK
                     "
     gene            30951..31277
                     /locus_tag="PC512_001542"
     CDS             30951..31277
                     /locus_tag="PC512_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2441288.1"
                     /translation="MKRKVYLFCSFGMSTSLLADKMQKVADEHNLPIEVEAFPIAEID
                     KIVEEKNPDCILLGPQVKYMLKELKPKFEAQGKLIDIINEVDYGTMNGEKVLKLAIKL
                     IKSKQA"
     gene            31316..32650
                     /gene="celB"
                     /locus_tag="PC512_001543"
     CDS             31316..32650
                     /gene="celB"
                     /locus_tag="PC512_001543"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HDF2441289.1"
                     /translation="MNRLERILMPLAEKIGKNKLLIAIRDGFLISSPLLIIGSLFLLV
                     ANFPIKGWNEFVGQIFGSDWAVKLQQPTVATFEVMTLLAVLGIGYSYAKQIDVDPIAS
                     AAVAIVAFFIITPFVIPYTPEGTESVYMVTGIPLGWMGSKGMFVGMITAITSVKLFAA
                     VVKKGWTLKMPDGVPPTVSKSFAALIPSAIVMVVFFLVKIAFEATPYGSIHEFIFKFL
                     QMPLLKLGNSLGAMAIAYIFLHLFWFFGINGSSVVGAVYNPILKILSAENLAAFQAGS
                     KIPNIITGQFQDMFATFGGAGSTLSLVIAMLLICKSKRIKSMGKLSILPGIFGINEPL
                     IFGLPIMLNPILLIPFAIVPTINIIIAYFCMSAGLVPLTNGVQLPWTTPIIFSGFLTT
                     GWQGAVLQVVLLILGIFMYIPFIKMLDKQYLREENATVEEEDDDISFDDLVL"
     gene            32661..33179
                     /locus_tag="PC512_001544"
     CDS             32661..33179
                     /locus_tag="PC512_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/betaine/sarcosine/D-proline family
                     reductase selenoprotein B"
                     /protein_id="HDF2441290.1"
                     /translation="MKKIVMILDQIQAGAGGKEKSNIPPAGKSSPLGPGIMMEQFLNE
                     SKVIATLFCGDEFFVNNEEEVTSKMIAMVKKLNPDVVICGPSFNYENFSKMSAILSKN
                     INDKTDIPAFAAMSEENIDVINEYKNDICIVKTPKKGGIGLNDSLNNICKLAKAIANK
                     EDITLMKEEFCY"
     gene            33275..34234
                     /locus_tag="PC512_001545"
     CDS             33275..34234
                     /locus_tag="PC512_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase"
                     /protein_id="HDF2441291.1"
                     /translation="MWGMIATWRMALEGITEASEHLEKGMEAGDAVELAVRRVEDYPF
                     YKSVGYGGLPNENCEVELDAAFMDGNTLDIGAVAGIRDYSNPVSIARKLSYEKVNNFL
                     VGIGAEDYAHKNGFERKNMLTDRAKLHYKKRKKETLDKGLSPYAGHDTVGMISLDKTG
                     KMCAATSTSGLFMKKRGRIGDSALSGSGFYVDSSIGGATATGLGEDLMKGCISYEIVR
                     LMKEGKHPQEACDIAVNELDKQLIKRRGKAGDLSLVAMNNKGEWGVATNIADFTFSVV
                     TKEESPTVYISNRVDGKTIHKVISNEWMEAYEARIKAPIEVSE"
     gene            34283..35335
                     /locus_tag="PC512_001546"
     CDS             34283..35335
                     /locus_tag="PC512_001546"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HDF2441292.1"
                     /translation="MNIISNKIDELKEDLLSDIIDIVKIPSVKGESENGFPFGEKVGE
                     ALNKALEISEKLGFKVRNLDNYIGYAEHGDSDDYVCVIGHVDVVHEGDGWKHQPYKGE
                     ETNGRIYGRGVLDNKGPIMSALYGLYAIKELNLKLDKRVRIIFGTNEESGFEDIPYYL
                     EKEKAPIMGFTPDCKYPVVYGEKGMAKIRIKSKINYEEDVYLGFIENMSENVLVTYKE
                     LNIENSDTILDIKVKYDFSYKLKDVLDEIKASFPNSIDIEVISNFNPVYFDKESNLVK
                     KLQLAYERVTSLDGTPVTTNGGTYAKVMPNIVPFGPSFPGQKGIAHNPDEYMDIEDII
                     LNAKIFANAIYELAKE"
     gene            35338..36012
                     /locus_tag="PC512_001547"
     CDS             35338..36012
                     /locus_tag="PC512_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HDF2441293.1"
                     /translation="MLEIIGMSVEDAKIIEDCGADRIELVSALTEGGLTPSFGLIESV
                     VNSVKIPVNVMIRHHAKSFVYSKEDISIMQKDISVVKEIGANGVVFGVLDKNNSIDEK
                     NLNVLLKCCDNLDVTFHRAIDESNTIDSVKILKDYDKITNILTSGGKGSIVDNIQMIK
                     NMMLSSNHIKILLGGGLNFNNIEKIKELTKASNFHFGTAIRINNSPFEDIDRQKLKQL
                     VNIISR"
     gene            36565..37116
                     /gene="raiA"
                     /locus_tag="PC512_001548"
     CDS             36565..37116
                     /gene="raiA"
                     /locus_tag="PC512_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HDF2441294.1"
                     /translation="MNIIISGKQIELTDAIKNKIETKLSKLDNYIHPDTDVKVTVSAR
                     KARQKIEVTIATVNGPIIRAEDMQENLYTAIDVVYDKLSKQLKKYKKRLQDKHKDNKS
                     IRFQDAEINLADEQEDYGDENQELVIQRRKKFSVKPMSEEEAVLQMELIGHDFYMFKN
                     IDSDEIAVVYKRNNGGYGIIEHE"
     gene            37248..39923
                     /gene="secA"
                     /locus_tag="PC512_001549"
     CDS             37248..39923
                     /gene="secA"
                     /locus_tag="PC512_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HDF2441295.1"
                     /translation="MSFMDNLFNMADKKELKKFNKTVDIIDSLEPKFESMADSELKNM
                     TNIFKERLANGESIDDILPEAFAVVREVSKRVLGLRHYRVQMIGGIVLHQGRIAEMKT
                     GEGKTLVATAPVYLNALTGKGVHVVTVNDYLAKRDRDQMAKIYEFLGMSVGVIIHGQN
                     PKVRKEQYDCDITYGTNNEYGFDYLKDNMVIHKEQRVQRGLNYAIVDEVDSILIDEAR
                     TPLIISGPGDKSTHLYSDANTFVLTLKPDDYELEEKDKAVSLTASGIQKAEVYFNVDN
                     ITDISHTELYHHINQALRAHVIMKKDVDYVAKDGEIVIVDEFTGRLMFGRRYSEGLHQ
                     AIEAKEGLKIQRESKTLATVTFQNYFRMYKKLSGMTGTAKTEEEEFKAIYKMDVFQVP
                     TNKLMIREDLPDCVYKSEIGKFNAVAQEIIERHKVNQPILVGTVSIEKSELLSQILKK
                     KGIKHEVLNAKHHDKEAEIIAQAGRLGAVTIATNMAGRGTDIVLGGNPDFLTKREMRR
                     NGFKEEIVNRVDTPIEGIPVKGNEILFEAREEYEKLFEKFKQQTQEEQKQVVEAGGLA
                     IIGTERHESRRIDNQLRGRAGRQGDPGSSRFYIGLDDDLMRLFGSDRISGIVDKIGLE
                     EDMPIEHRILSKSIEGAQKKVEGKNFGIRKHVLQYDDVMNKQREIIYAERKRVLEGED
                     LQEQIQSMTHSIIEEAVTLYTQDKGFDEEGFKEHMYNLFLPKGSIEIPEIEKLNPVEI
                     TEKVYEIAMKIYTSKEEQVGYERMREVERVILLQAVDNHWIDHIDAMDQLRQGIGLRA
                     VGQQDPVIAYKMEGFDMFDEMNKHIKEDTVRYLFNITIETPVERKAVVDVENLSSPSD
                     GTLPTSKTVKKDEKVGRNDLCPCGSGKKYKNCCGR"
     gene            39938..41045
                     /gene="prfB"
                     /locus_tag="PC512_001550"
     CDS             join(39938..40012,40014..41045)
                     /gene="prfB"
                     /locus_tag="PC512_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_153309863.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HDF2441296.1"
                     /translation="MLKLQEYRHSMEQMASNLEELRVSLDIASLMKNIQINEEKMNKQ
                     DFWNDNEVAQRVLQENKSLKETLEEYESLKSLLEDIEVLIEIGLEEDDDSVERDIEKS
                     IESMEEKLSEMKIKTLLNGEYDKNNAILSINAGTGGLDAQDWAQMLLRMYIRWSESKG
                     YKVKLLDIISDPEAGIKTATILVEGTNAYGYLKSEKGVHRLVRISPFDPSGKRHTSFA
                     SIDVTPELDENIEVEINPSDLKIDTYRASGAGGQHVNTTDSAVRITHIPTGVVVQCQN
                     ERSQHLNKDRAMRLLMAKLIELKELEQKEKIEDIQGKYSQITWGSQIRSYVFQPYKLV
                     KDHRTNAEFGNVDSVMNGNIDLFINEYLKMNKIV"
     gene            41189..43330
                     /locus_tag="PC512_001551"
     CDS             41189..43330
                     /locus_tag="PC512_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011010799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HDF2441297.1"
                     /translation="MDINQILKKEFNLRDEQINNTLKLIDEGNTIPFIARYRKEMTGE
                     MSDVTLREFYEKLMYLRNLQSRKDDVVRLIDEQGKLTDEITQNIEKAKTLQEVEDIYA
                     PYKQKKRTRATIAKEKGLEKLALSILENNLDNIEIEAKNYLDEEKEVLSIEDALKGAR
                     DIIAELVSDDAKIRKYIRELALREGMIVSKSATDEKSVYDMYYDYSEAVKSMPPHRVL
                     AINRGEKENFLKVKLEINNDKVLNYIINEYVNDKNFKNKEEIVSSIEDSYKRLIFPSI
                     EREIRNHLTEIAQERAISVFGKNVKSLLLQPPVKDKVVMGFDPAFRTGCKIAVVDKNG
                     KLLDYTTVYPTDPQNDVEGAKKVLKGLIEKYDIDIISIGNGTASRESETFVSEMIKEI
                     DNEVQYVIVSEAGASVYSASELANEEHPDINVSIRGAISIARRLQDPLAELVKIDPKS
                     IGVGQYQHDLNKKRLEEVLDGVVEDSVNSVGVDLNTASYSLLEHVAGISKTIAKNIIA
                     YREENGDFTSRAQLKKVKRLGPQAFTQCAGFMRILEGKNPLDNTGVHPESYDICKKMI
                     EIIGYSLDDVKNKNICEIDEKIKEIGLRELSEKLEVGQVTLKDIITEIKKPGRDPREE
                     GIKPILRTDVLKIEDIQEGMTLKGTIRNVVDFGAFVDIGIKNDGLVHKSEMSNSFVKD
                     PMSIVTVGDIVDVKVIGIDLNKKRVALSMKK"
     gene            43478..44644
                     /locus_tag="PC512_001552"
     CDS             43478..44644
                     /locus_tag="PC512_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2441298.1"
                     /translation="MIFIKNGKINTITNGIIHGDILIDEGKIIEIGEDLIAPLDVEVI
                     DASNKLVFPGFIDAHTHLGLWEDGIGFEGADGNEETDPITPQLNPIDGINPMDRTFKE
                     AFEGGITSVCTTPGSANVMGGQCIAIKTCGKRIDKMVIKNPVASKIAFGENPKSCYGQ
                     DDKSPQTRMAIAALLRENLKKAEEYLEDIDMYESHDDEDCEKPEYDIKMESLIPVLRR
                     EIPFKAHAHRADDMFTAIRIAKEFNLKLTLDHCTEGHLIVDELVEEGFPVIVGPSLSE
                     RSKFELRNLTFNTAGILSNAGLDVCIMTDHPVIPVQYLPICAGIAVKHGMKEEKAIES
                     ITINPAKTLGIEDRVGSIEVGKDADLVIWDNSPLEIQSNVLYTIINGKVVYEKK"
     regulatory      44704..44821
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            44945..45550
                     /locus_tag="PC512_001553"
     CDS             44945..45550
                     /locus_tag="PC512_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDF2441299.1"
                     /translation="MQNTAKRGNMISTRTLVVMSILSAISYLLMFIQAPIPGIFPDFL
                     KIDLSDIPAIFGGMSLGPFVGFGIVVVKNVLQAITATTTGGIGEFANILIGGSYVMIL
                     CYSYKRSGDLKGVLIGFVLGTISMTIIGSLVNYFVMLPLYGQLMGLDAIIGLGSAINP
                     QVHDLFTFVIWMIAPFNVLKAVILSLVTLPLYKKMGNVIKK"
BASE COUNT        18438 a         5023 c         8764 g        13611 t
ORIGIN      
        1 ctaggttcta taaacttatt aaaaacttaa tagaaatatt aagcataaag attatgtggt
       61 tacaatagca gagaggatac acctgttccc atttcgaaca cagaagttaa gctccctagc
      121 gctgatggta cttggtggga aactgcctgg gagagtagga cgtagccacg ttaaatgttc
      181 caaggtagct caacggtgga gcaaccggct gttaaccggt aggctgtggg ttcgagcccc
      241 acccttggag ccaaaaaagc cgaagtggcg gaactggcag acgcacagga cttaaaatcc
      301 tgcgggactt acctctcgta ccggttcgat tccggtcttc ggcacttata aaacaatatc
      361 gcggggtgga gcagttggca gctcgtcggg ctcataaccc gaaggtcgta ggttcaagtc
      421 ctgcctccgc aaccattaaa acggctcgtt ggtcaagagg ttaagacacc gccctttcac
      481 ggcggtaaca ggggttcaat tcccctacga gtcaccaatt caattaaata tgcgggtgta
      541 gctcaatggt agagttctgg ccttccaagc cagctgtgag ggttcgatcc ccttcacccg
      601 ctccaaaaat gggaccatag ctcagctggg agagcacctg ccttacaagc agggggtcac
      661 aggttcgagc cctgttggtc ccaccattcg cggcctggta gttcagttgg ttagaatgcc
      721 agcctgtcac gctggaggtc gagggttcga gccccttcca ggtcgccaaa ttaaataagc
      781 gggaatagtt cagtggtaga gcgcaacctt gccaaggttg aagtcgcgag ttcgaatctc
      841 gtttcccgct ccataataac ttgggtgcat agctcagctg gatagagcaa cgcccttcta
      901 aggcgtgtgt ccggggttcg aatccctgtg cgctcattaa gaaaagttta ctataaatta
      961 tagtaaactt ttatattgtt taaaaagaca caggaaacat gtatattacc tgtgtctttt
     1021 tatttataaa ctttaaacta tgtaaaaatt acagtatatt ctaatagagt tacagtatat
     1081 tcattaatat tgtaaacata cggagggtaa tgtataatag tctacaagat gtttatgaag
     1141 gcatcagtta aatataataa atataactaa ttagtaagag ttatatacat tatattgtat
     1201 actttatggt atttatatat tgaaataact tatgaaatta tttataaaga gattcatgag
     1261 catatttttg tctaaacaat aagtataaga aattataaaa agttagagac tatagtgaat
     1321 ttacaattta atgtaatatt tataagttat actaaataaa ttattatact gtgaaatgga
     1381 tatataactt taggtattgt gtattatttt cactgtagga gattatatct agttatacat
     1441 aataagtttt aatgatagtt tatagtaaga tattaaaata aatttatcta atctagatat
     1501 gaaataagtt attactttaa tataaaaatg aatctaatgg aataatattg atgataagta
     1561 atatttagat tttgtatttg tttatagtta ataagtggat tatagaattt ataataatta
     1621 atatatatta aacaaagata tattaagata ttttagaaca taaaactgaa ttaaggcgcg
     1681 agtactattt tgtattcgcg ccttgatggt ttgagttatt tgagtaaaaa ctaactttaa
     1741 taagaaatat gtatttatta agttgatatt tttaatgtgt ttagagatta tttaacaatc
     1801 tccaaatata aaactagaat tatttacata aaagttaaat agtttgtata gagttagatt
     1861 tatatagtat aatacttagt gtaaataatt aagaagttat caaacaggag gataaaactg
     1921 tgttagatat aaattctttt ttaaatggat tttttaatat aatattaaga atgagtatat
     1981 atgatttaat tgacatatct atagtagcgt atatttttta caaaatattt atgtttataa
     2041 aagatacaag agcagaacaa gtgtttaaag gtataatatt tcttttatta gcaactcaac
     2101 ttagtaacac ctttaaattg cataccgttt attggatatc tcttaaagct ttagattatg
     2161 gagttatagc tgctcttata atttttcaac cagaatttag agcaggactt gaacatatag
     2221 gaagagcaaa gtttaattta tttggaaaga atgtaaatac ttctgaagaa actctcaata
     2281 gaaatataga agaaattgta gaagctttat attcactttc tagacaaaaa ataggagctc
     2341 ttatcataat ggagagagaa actagaataa gtgatataat aaatacagga actattattg
     2401 atgctgaaat ttctaggcaa ctattaataa atatatttat accaaataca ccattacacg
     2461 atggagctgt tgtaattaga gattctaagg taaaagcagc tgcatgtttt ttgccattga
     2521 cagaaagtaa ggatttaagt aaagatttgg gcactagaca tagagcagga ataggggtaa
     2581 gtgaggtgtc tgactgtata actttgattg tatcagagga aacaggtggc gtatcaattg
     2641 ctaaagcagg taagttatat agagatattt ctagagaaag aatgatgaat atattacgta
     2701 gtaatttaaa aacaaataca gaaacaagaa gttttttcaa aggtggtata tttaaatgat
     2761 aaatagacta aaaaataata ccaaaataaa aataatatca tttttaagtg caattgcatt
     2821 atggatgtat gttatggctg tagttgaccc tgaagaaact aaagggtttg aagatatacc
     2881 tgtatctata agtaatatga gtgatttaaa ggataaaaat cttgttatat atccagacga
     2941 aaaattaaca gcagatgtat atataaaagg tagtttatca aaggtacaaa gtgttaaaaa
     3001 agaagatata catgtatatg gaaccattga agacccaata caaggacaga aggaagtata
     3061 tttaaaagca aatattcctc aaggtgttac tctagaattt aagcatgatg ttttagtagt
     3121 aaatcttgaa aaaaacataa aagaaaaaag agatataaag gtagaagtaa gtggaaattc
     3181 aaaaagaaat ataaataaaa ttgaacttag taaggaattt gtcgatgtat caggtccaag
     3241 aactctagtt aaagaagtca aaagtgtaag agctaatcta gatgttggta atgagacaga
     3301 tgatttttct aaaaaattgc aattaatacc attaaatagt gatggaacta aggttgaagg
     3361 agtaacatta agttcatcct ttgtgactgc aaagatagag ctattaaagg aaaaaattgt
     3421 cccaataaga gtaagtctaa atgataataa agataatgat gtactgaaaa actataaatt
     3481 aagtaaggaa caagttacaa taaaaggaaa gaaagaagat atagacaaaa taagttatat
     3541 taagacaaaa cctattgact tagctgattt ggctaatggt gaagaaaaag aagttagctt
     3601 agaaattcca gagggtataa ctcttgagga tagctctata acaattaaat taaatgatac
     3661 aaaacaattg agtgcagaat ttttatataa tgcgggagat attgaattaa gaaatatccc
     3721 aacaaatatg gataatccaa atgtaatttc tgatgtagat ataaaagttg ttgtagagtc
     3781 aacggaggat ttgagtaagt taaataaaaa agatatttca ttatatattg atttatcaca
     3841 aggtcctgag gaagatagta aatataaaat aaaatatgaa acaacatatc aatttaaaaa
     3901 aataaatata gaacctaata ttgttgaagt ggaatgaaca aatatttcga atatttagtt
     3961 gttacaagat gcgacaaaaa aacctataaa attaagtttg ttaattttat gtttttgttg
     4021 catcttgttt attttagtta tattataaaa taaggacaat gagatatttg ttaaatctaa
     4081 aaagcgctag atatatgaaa aaagactgat aaatagattt aaataaatat tttgaattaa
     4141 atatttcaat tatctctagg aaaacgttgc tgaacgagtt ataatttaat tgagatataa
     4201 aaagttctat ttcaaaaaat tcaagatgag gtggaaatgc atgagaagtt ttgaagaagt
     4261 aattaagttt gcaaaagaaa gaggacctaa aactatatca gtagcatgtt gccaagataa
     4321 agaagtttta atggcagttg aaatggctag aaaagaaaaa atagcaaatg ccattttagt
     4381 aggagatata gaaaagacta aagaaattgc aaaaagcata gacatggata tcgaaaatta
     4441 tgaactgata gatataaaag atttagcaga agcatctcta aaatctgttg aattagtttc
     4501 acaaggaaaa gccgacatgg taatgaaagg cttagtagac acatcaataa tactaaaagc
     4561 agttttaaat aaagaagtag gtcttagaac tggaaatgta ttaagtcacg tagcagtatt
     4621 tgatgtagag ggatatgata gattattttt cgtaactgac gcagctatga acttagctcc
     4681 tgatacaaat actaaaaagc aaatcataga aaatgcttgc acagtagcac attcattaga
     4741 tataagtgaa ccaaaagttg ctgcaatatg cgcaaaagaa aaagtaaatc caaaaatgaa
     4801 agatacagtt gaagctaaag aactagaaga aatgtatgaa agaggagaaa tcaaaggttg
     4861 tatggttggt ggaccttttg caattgataa tgcagtatct ttagaagcag ctaaacataa
     4921 aggtataaat catcctgtag caggaagagc tgatatatta ttagccccag atattgaagg
     4981 tggtaacata ttatataaag ctttggtatt cttctcaaaa tcaaaaaatg caggagttat
     5041 agttggggct aaagcaccaa taatattaac ttctagagca gacagtgaag aaactaaact
     5101 aaactcaata gctttaggcg ttttaatggc agcaaaggca taattttaag ggggaaatag
     5161 gcaaatgagc aaaatattta aaatcttaac aataaatcct ggttcgacat caactaaaat
     5221 agctgtattt gataatgagg atttagtatt tgaaaaaact ttaagacatt cttcagaaga
     5281 aataggaaaa tatgagaagg tgtctgacca atttgaattt cgtaaacaag taatagaaga
     5341 agctctaaaa gaaggtggag taaaaacatc tgaattagat gctgtagtag gtagaggagg
     5401 acttcttaaa cctataaaag gtggtactta ttcagtaagt gctgctatga ttgaagattt
     5461 aaaagtggga gttttaggag aacacgcttc aaacctaggt ggaataatag caaaacaaat
     5521 aggtgaagaa gtaaatgttc cttcatacat agtagaccct gttgttgtag atgaattaga
     5581 agatgttgct agaatttctg gtatgcctga aataagtaga gcaagtgtag tacatgcttt
     5641 aaatcaaaag gcaatagcaa gaagatatgc tagagaaata aacaagaaat atgaagatat
     5701 aaatcttata gttgcacaca tgggtggagg agtttctgtt ggagctcata aaaatggtaa
     5761 aatagtagat gttgcaaacg cattagatgg agaaggacct ttctctccag aaagaagtgg
     5821 tggactacca gtaggtgcat tagtaaaaat gtgctttagt ggaaaatata ctcaagatga
     5881 aattaaaaag aaaataaaag gtaatggcgg attagttgca tacttaaaca ctaatgatgc
     5941 tagagaagtt gaagaaagaa ttgaagctgg tgatgaaaaa gctaaattag tatatgaagc
     6001 tatggcatat caaatctcta aagaaatagg agctagtgct gcagttctta agggagatgt
     6061 aaaagcaata ttattaactg gtggaatcgc atattcaaaa atgtttacag aaatgattgc
     6121 agatagagtt aaatttatag cagatgtaaa agtttatcca ggtgaagatg aaatgattgc
     6181 attagctcaa ggtggactta gagttttaac tggtgaagaa gaggctcaag tttatgataa
     6241 ctaatgataa aagaataaga atcataactg gtcactatgg aagtggtaaa agtgaatttg
     6301 cgatgaacta tgttgttaag ttaagagata tggtttctgg caaagttgct atagccgatt
     6361 tagatgtggt aaatgtatac tttagaacta gagaaaagaa agagttaatg aaatccttag
     6421 gtatacaacc aatagatagc tcaattaatg ctccaacatt agatttacca gcagtatcag
     6481 cagaggtaat gtctcctatg gtagaccatt catacaattc tgttatagat ttaggtggag
     6541 ataatgtagg tgctagggtt ataggaagat ttagtcattt gttaaaagaa ggcgattatg
     6601 atatgctttt tgtaataaat gcaaataggg agaaaactca aacttctgaa gaagttatcc
     6661 aatatataaa agaaatagaa aaatcttcta aattaaaggt aacaggtcta attaataata
     6721 ctcatcttat taggtttact actattgatg atgttttaag aggtcagaaa gttgcaaaag
     6781 aagtttctga aaaatgtaat ataccgataa gatatgttgc atgtttagaa aatcttgttg
     6841 aacagttacc aaaagattta gaaggagaaa tttttcctat aaaattatat atgagagaag
     6901 actggatgta gtttgagctc aaatatatag aaagtttaag gaggcttagg taaatggcta
     6961 aaggaaaagt atcttttaat caagaacgtt gtaaaggttg tggattgtgt gttgaagcat
     7021 gtccagtaaa aatcatacaa ttagactcaa atgtaataaa caaaaaaggg tataacccag
     7081 caactgtttt tgaaatggaa aaatgcatag gatgtgcaag ttgtgcaact atgtgtccag
     7141 atgtagttat aacagtagaa agagattaat ttaattaata tttaaggggg aattttaatg
     7201 gctaagatac ttatgaaagg taacgaagca tttggaaaag cagctataga agctggttgc
     7261 aaatatttct tcggttaccc aataactcca caaagtgaat taccagaata tttatcaaga
     7321 gagttaccta aaataggtgg agcgttcgtt caagctgaat cagaagtttc tgcgataaac
     7381 atggtttatg gtggagcagg tgcaggagca agagttatga cttcttcatc ttcaccagga
     7441 gttgctttaa agcaagaagg tataacatat gcagtaggag cagaagttcc ttgtgttgta
     7501 cttaatgtaa tgagaggtgg tccaggactt ggaagtatac aaccttcaca agctgactac
     7561 tttatgtcta caagaggtgg aggaaatgga gactacagaa ctccagtatt cgcaccagct
     7621 acagttcaag aagctgttga tatgataatg gaagcttttg acgttgcaga ttattacaga
     7681 tcaccagtta tggtagttgc agatggtatg ataggtcaaa tgatggagcc agttgaattt
     7741 agagctcctg agaagaaaag agaattgcct cctaaagatt gggcaactgt tggaactaaa
     7801 ggaaaaagaa aacctaatgt aataaactct ctatacttag agccagaagt actagaagac
     7861 cattgttggc atttacaaga aaaatttgat gcaatggaaa agaatgaagt acaatacgaa
     7921 atgtacaaaa cagaagatgc tgaatttgta tttgcagctt atggaactac ttcaagagta
     7981 gtaaaaagcg caattgatat attaagagaa gaaggaataa aagcaggtct tataagacct
     8041 aaagtattat ggccattccc attcgaagca ttcaaccaaa ttcctaatgc tagaaacata
     8101 ttgactgttg aaatgagtat gggacaaatg gtggaagatg ttaaaatggc agtagaaggt
     8161 aaattaccag tttacttcca tggaagacca ggaggaatga ctccaacacc agcagaaata
     8221 gttgaaaaag ctaaaaaaat tattgccgga gaattggttg caggaggtgc tagataatgg
     8281 ctgttgtatt taagaaaact gaaggattac aagatactca aactcactac tgtccaggat
     8341 gtacacatgg tataatccat agattagttg gtgaagtatt agaagaacta ggagtattag
     8401 gtgatgctgt aggtgttgtt ccagttggat gttcagtttt aggatataaa tattttaact
     8461 gtgacactca agaagctgct catggtagag cgccagctgc tgctacagga ataaaaagag
     8521 ttcatcctga aaatacagta ttcacttatc aaggtgatgg agacttagct tcaattggta
     8581 ctgctgaaat agttcatgca gctgctagag gagaaaaaat aactactata tttgtaaaca
     8641 atacaactta tggtatgact ggtggacaaa tggctccaac tacattagtt ggacaaagag
     8701 ctactactgc tcaatcagga agaaatgctg aaactcaagg ttatccaata agagtaagtg
     8761 aaatgttagc tacattaaca ggagctgtat ttgtagaaag agtagcagtt gatactccag
     8821 ctcatgttag acaagctaaa aaagctataa agaaagcatt ccaagttcaa caagcaggat
     8881 taggatttgg aatagtagaa gtattatcta cttgtcctac aaactgggga ctagctccaa
     8941 acgatgcttt acaatggtta agagacaaca tgataccata ctatccatta ggaaatttca
     9001 aaaatgttga agttgaggag gtgaagtaaa tgtctacagc tagagtaata tgtgcaggct
     9061 tcggaggcca aggtgttatg tctatgggac aattacttac ttatgcagga atgctagaag
     9121 gaaaagaagt ttcttggtta ccatcttatg gaccagaaat gcgtggaggt acagcaaact
     9181 gtgcagtaac tgtatctaat gagccagttg gttctccact tataacagat gatgcaactg
     9241 cagctatatt attaaatata ccagcatttg aaaaattcaa agatgatgtt attcctggtg
     9301 gaaaaataat agtaaatagt tctttaataa aagaaaaagt tgatagaaca gatgtagatg
     9361 tttattatat accagcaaat gaattagcag ctgaattagg aaatgataaa gttgctaaca
     9421 tgataatgtt aggtgcttac ttaaaagtat ctgatactgt agatatagaa tctgtactag
     9481 aagcattcaa aaaagttttc ggacctagaa aagaaaaatt cgttccatta aacagagaag
     9541 ctttacaaaa aggtatggat gctacatgtt ctaaagcaac taactaataa agaaaaagat
     9601 gtcaaaaaaa agacaataga attatttcta ttgtcttttt tgctgataag tattaaaata
     9661 tttttatgac tgaaattaag cctataatga tattttatga actataaaaa tataatacaa
     9721 attacaagct tttcaattat gaaaggagaa tctttagtga gaaagtattt tggaacagat
     9781 ggagttagag gagtagcaaa tacagaacta acatgtgatt tagcatataa acttggtaga
     9841 gctggtggat ttgtcttagc tcaaggagac cacagagtaa aagtagtagt aggtaaggat
     9901 actagaatat caggtgatat gttggaagca tctttaatag caggacttat gtctgttgga
     9961 tgtgatgtta ttactgttgg aataatacca acacctgcag tggcatattt aactagaaaa
    10021 tatggtgctg attgtggtgt ggttatatct gcatctcaca atcctgttga atataatgga
    10081 atcaaattct ttaataagaa tggatataaa ttagatgatg aaattgaatt gaaaatagaa
    10141 gaatatatag acgatataga caaaattgat tgtcttccaa ttggtgaaaa tgtaggaaga
    10201 aaattacatg aacattgtgc acaaagagac tatgtagact acctaaaatc aataataagc
    10261 actgacttta agggattaaa agtagttttg gactgtgcta atggtgcgtc atataaagtg
    10321 gcaccaatag tgtttgatga actaggagca agtgtaattt caataaatag ttcaccagat
    10381 ggaaataata taaactataa atgtggctct acacatccag aacaacttca aagggctgtt
    10441 ttggaacata atgctgactt aggtcttgca tatgatggag atgctgatag attaattgca
    10501 gtaaatgaaa agggtcaaat tgttgatgga gaccatataa tgatattgag tgccttaaat
    10561 ttaaagaaaa ataataaatt ggcacaagat actttggtag ttacagttat gagtaatata
    10621 gggttgacaa tagctgctaa ggaaaatgga ataaatttat ctactacagc agttggagac
    10681 agatatgttt tagaagatat ggttaaaaat ggatataatc ttggtggaga gcaatctgga
    10741 catatgatat ttttagatta caacactact ggagatggag tgcttagttc tctaatactt
    10801 gcaaatataa tcttgcaaga aaagaaacct ttatcagaaa ttgcatcaat aatgagccaa
    10861 tacccacaag tattagtaaa tgcaacaata aaaaatgaaa ataagaacaa atatatggaa
    10921 tatccagaaa taaaaactga gatagaaaga atagaatcta ttttagacgg aaatggtaga
    10981 gttttgataa gaccatcagg aactgagcca ttagttagag ttatgttaga gggtaaagag
    11041 gaaggtcaaa taaaagaatt agcaacaaac ttagctaatc ttatacaaga aaaattatcg
    11101 taatttaaag ggtattctca gatataaata ctgaggacac ctttctaagc gccagaactt
    11161 agttatagac ataattattg agtaatatag gaactaagtt gacgaggtca gagttaatcg
    11221 aattgtcggc ggatgctctg cggtgtgttt accatcgaaa gacttcttta aataatagga
    11281 gcaatcctat ggacaaaggg aagccaaagt aaacttatat gacctaactc ttaaaatata
    11341 taaataatat ttttaggagg acacaaataa tgtgtggaat agttggatat ttaggaagta
    11401 gaaaggcagc agaagttata gtagaagggc tttctaagct agagtacaga ggttatgact
    11461 cagcaggagt agcagttaat agttctaatg aaaaagaact taatattaga aagtttaaag
    11521 gtagactttc tgtacttgca gaagacttag aaaagaatcc tattgatgga aatttaggta
    11581 tagggcatac gagatgggca actcatggag aaccatctga tgtaaactca catcctcatt
    11641 ttaatcaagc caaaacaata gcagttgttc ataatgggat aatagaaaac tatatggaaa
    11701 taaaagaaga attaatttct gaaggtgtta agtttgaatc tcaaacagat acagaggtaa
    11761 tagcacattt agtagataaa tactatgagg gtaatttatt agatgctgta tacaaaacta
    11821 tatcaaaatt aagaggagct tatgcattag gtgttatatg taaagaacat ggaaatgaat
    11881 tagttgcagt aagaaaagat agtcctcttg tagttggtgt tggtgaaggt gaaaacttta
    11941 tagcatcaga tatacctgca ttattaaaat atactagaga tgtttatttc ttagaaaatg
    12001 gagaagtagt tcatctaaaa gacgaaaatg taacagttta tgactctaat agaaatcttg
    12061 ttgaaaaaga agtatttcat gtaacttggg atgtagaagc tgcgtctaaa ggtggatatg
    12121 actactttat gtcaaaagaa attcatgagc aaccaacagg agtaagagaa actttagaaa
    12181 gaagacttga tgataatgga aatataattc tagacagtat aaatatttct aaagaagact
    12241 tagaaaaaat aaataaagtt tatatagtgg cttgtggaac agcatataat gctggattac
    12301 ttggtaagta tgccatagaa aaatttgtaa atataccagt aataactgat atagcatcag
    12361 aatttagata tagcgaccca tttgtagatg aaaattcatt agtaatatta gttagtcaat
    12421 ctggtgagac agcagatact ctagcagtat taagagattc aaaggctaaa ggagcaagaa
    12481 tactttcaat aactaacgtt gtaggttcat ctatagcaag agaatcagat gatgtattct
    12541 atacttgggc aggacctgaa gtagcagttg catcaactaa ggcatatact actcaaataa
    12601 cttctttata catgatagct ttagactttg ctatcaaaaa aggaacaata actagagaat
    12661 tttatgatag tatgatttct aagatgaaag aaataccatc aaaaatacaa gaaatactag
    12721 acaatgaaga atatataaaa gaagttgcta aaacagttgt tagttctgaa catgcattct
    12781 atttaggaag aggtatagac tatagcttag caatggaagg ttcattgaaa ttaaaagaga
    12841 tttcatatat acatgcagaa gcttttgcag caggagagct aaagcatgga acaatagctt
    12901 taatagaaaa aggaactcct gtaattgcca tagctactca agaaaagtta tttgaaaaaa
    12961 tggtttctaa tatggaagaa gtaagagcaa gaggagctta tgtagtagca atagctcaaa
    13021 gccataataa ggatgttgag aaagctgctg ataaaataat ctatatacca aattcagatg
    13081 atattttatc accaatatta gcagttgtac caatgcaatt acttgcttat catgtctctg
    13141 tactaagagg atgcgatgta gataagccaa gaaatctagc taaatcagta acagttgaat
    13201 aaaaacagat taaaaattaa atagataata tttattgaaa agaactcatc ctgttatttg
    13261 tattttatag gatgagtttt ttaaataaat attaaatttg ttttgttttt gctataataa
    13321 attttataaa aagattgata ttaaatcatc tgtaaaatga taaatatata gaccatacca
    13381 ggtataggga acgataaata tagttcatat aaaatatagt gagtacttaa taaacatata
    13441 gtcaatatca gataaaaaaa ataatagctt atgagaaaaa ttaaaataca aggtattagt
    13501 aaccttgtga taagataaag tgagtagttt aaaataagaa tataaggaac tatttataaa
    13561 agaatataat gaagctaata aagtataaga aaattacttt attttagtaa aataatttca
    13621 aataaaaatt ttttaaattg ggagtataaa ttatgacaaa tgattttaaa aaagaaaaga
    13681 aagaagatta ttttgttaat cttaaggcaa tatctactga agttttacaa gaaaaagtgc
    13741 aagataacgc ttgggttata gttgatactc gcttaaatga tgcttataat ggctggaagt
    13801 tagatggagt aaaaagaggt ggacatataa aaggagcagt agatttttct gctaattggt
    13861 taagtgtata ctcagataga aaagatgaag tgctagaaca agcattgaaa actaaaagaa
    13921 ttgatttaga taaaaatata gtattatatg atgcaaatgg aaaagatgct ttggttgtag
    13981 cagattattt atctaaaaaa ggatataaat atctatataa atatgatatt aaacaatggg
    14041 cagacaacga aaatcttcca atggaaagat ataaaaatta tcaaatgata gttcctgctt
    14101 ttataataaa agatatatta gatggaaaaa ttcctgagac atttgaagat tcaaagaata
    14161 taaaaatgat tgaagcgagt tggggagaag aatcgtatac aaaagggcat atacctacaa
    14221 gtgttcatgt aaataccgat attatagaac ctcctccaac atggatgctt gataatgatg
    14281 ataacttaat taagtttgct ttagactatg gattaacaaa ggatgatact gtaatagttt
    14341 caagtagtac acctatggca tcttatagac tagctgttat attgagatat ataggagtaa
    14401 aagatgtaag agttttgaat ggtggaacaa actcatggtt atcagcagga tatgaattag
    14461 aatttactag taatccaaaa cattcatgta ctaattttgg agcagatata ccagttaact
    14521 cacaattagt tgttactacc tctgaattaa gacaaaaact aaaagaaaaa aataagttta
    14581 tactagtaga taaccgtact tgggatgaac atataggaaa agtatctgga tatacatatt
    14641 atgataaaaa agggcgtata ccaggagctt tatatggaca ttcaggtagt gatagtgttt
    14701 cactagaaga atatcgtaat attgataata caatgagaaa taaatatgag attttagaaa
    14761 tgtgggacaa ggaaaatata gatgtgaata gacagcttat atttatgtgt ggaagtggat
    14821 ggcgtgctgc tgaagtatta acatacgcaa atgtcatagg agtggaaaat acctcccttt
    14881 atagtgatgg atggatgggc tggagtcttg ataattcaaa tttaattgaa gtgggagaac
    14941 acaaataaag tttttgaaag tacgatagag ttgtttaaaa caaaggtgtt tttgatttat
    15001 tgggaagagt gtgtaaattg tgttttggga agtgtactta ggtatgttca tttggagcta
    15061 tggaaattga taaaaaagta ttatctgttt attttgctgg taaaatgtga atagattata
    15121 gattatagat tatagattat agatttaagt atagactaag taatttatat tacagaagag
    15181 aatatataag aactagtgca agatgtattt gatacatata aaaaattggc aaatccagaa
    15241 taaggataga gaaaattgag attgaagagt ttgaaagaga cttattagat gaaaaataca
    15301 aagatgtata aaaatacata ttgagaaagt atatctctct taaatttgtt aataattcta
    15361 ttatacagaa aaacatattt aagggggatt ttttactatg aaaagagtaa aattagctat
    15421 aagctttttt atattaatga ttatagggat gacaatatct tatgcagata caagtataaa
    15481 tactaaatac aatagattaa gtaaagctct tgaaatttca gaagcaaatt ttaaatttta
    15541 taatgttaaa attaattctg ttataaatca taatttatca aataaagaat ttcataatat
    15601 ttttatagaa ataattaaca atctaaagtt ggataaaaaa ggaataaatt ggaatcaaaa
    15661 agggtctggc gataaaatac aattatgtgc tactataaaa ggtagcgata aagaaatttc
    15721 tataaaagga ataaataaaa ataacaaaga aagttacata gtagttgaca tattggataa
    15781 caaagtatat aaacataaag aggttattta tagtaacgta gaaaatgtgt taaataaata
    15841 ttcatctcaa gtagatgtgt ctgcttgtat tgttggagaa tacacaaaaa ggttacaaaa
    15901 caacaaatat gatgatattt tacaaaaaat attatataat atgagtgcta agcaaataga
    15961 tgaagtgaaa gacgtaaact ttttatctat aacagcatat agtaaagtat taaatgatta
    16021 tgaattagaa tatttagggg aaaaaattaa tttaaatata ggaattaaat ataatgagga
    16081 cgacggaaga acactcatat atattgccac accaattata aaattagatt attaattatg
    16141 aggagatcaa aaaatatggc taagataata gtaaaaaaga gtaatccact taaaggtagt
    16201 gttaaaatag atggtgcaaa aaatgcagtt ttaccaataa tagcagcgac tttattagca
    16261 aacgggaaat caacattaaa tggagtacca aatttaagag atgttcatgt tatatcagat
    16321 ttattaagac atgtaggggc agaagttgaa tataaagaaa atacacttac tgttgatgca
    16381 agtaatataa aaacttgtga agctccatat gagcttgtaa gaaagatgag agcttctttt
    16441 ttggttatgg ggccattgct tgctagattt aatagtacga aaatttctat gccaggagga
    16501 tgcgctatag gaacaagacc tatagattta catttaaaag gatttaaagc cttaggtgca
    16561 aagatagaaa tggaccatgg ttttgttgaa gcagcaacag aaaaattagt aggaaataaa
    16621 ttatatttag atttcccatc tgttggagca actgaaaaca taatgatggc agcttcttta
    16681 gcagaaggga ctacaataat agagaatgca gcagaagagc cagaaatagt agatttagca
    16741 aacttcttga acgaaatggg agcagatgtt aaaggtgcag gtactaatac tataaaaata
    16801 aaaggtgtta aagagttaaa aggagcagaa cataatgtaa ttccagacag aatagaagca
    16861 gcaacttata tggttgcagc agctatgaca aaaggtgata taactgttga aaatgtttta
    16921 atggagcatt taaaaccagt tgtagctaaa ttaagagaag ctggttgtga aataacagaa
    16981 atggacaatt ctgtaagagt tgtaggtcca aaagtattaa aaccaataga tataaaaact
    17041 ttaccacatc caggatttcc tacagatgtt caagcacaat ttatggctat gcttactgta
    17101 gctaatggaa ctggtgtagt tatagaaact gtttttgaaa acagatttat gcatgttgct
    17161 gaatttaata gaatgggtgc taatataaaa atagatggaa gaagtgcggt tgttaatggt
    17221 gtagatgagc tacatggtgc agcagtaaac gctactgatt taagagcagg ggcagccctt
    17281 attttatgcg gtcttatagc agaaggagaa actcaaatag gagaaatata ccatatccaa
    17341 agaggctatg ttgatataga taagaagata acagcattag gtggtcaaat cgaaatagta
    17401 gaagattaat aattggttta tagaagaaag ttataaatta atagggttgt tcatatactt
    17461 aaatacaagg ttttaaaagc taaggaggag agtatatgaa gaacccattg gttgttttgt
    17521 taggatttgt gacttgctct gtgttagttc catcacttat aactttagtt tcttataaaa
    17581 atgtagaatt aactgaaaaa gcagagagcc cagtatctat aaacaaaact attaaaaaaa
    17641 gtgatattga agacaaaggt aataaagaag aaaaaaatac agtgaactat gaaactgtaa
    17701 ataaaaaagc accaattatc aatgtatata atcatataac agggaaaacc gaaaagatgg
    17761 acatggagaa ctatttatgt ggagtactag ctggtgagat gtcttcagag tttgatatag
    17821 aagccttaaa agctcaatct gtagcagcta gaacatatgt agtatataaa caggaacatg
    17881 gtaaatctag taaacataaa aatgcagtag tatgtactga ttataaacat tgtcaagaat
    17941 ataagagtta tgatactctt aaaaaattaa atggtgaaga atggattaag aataaatatt
    18001 ccaaaatcca agaagcagtt agaggaacta aaggtcaaat aataacttat aacgataagg
    18061 cgatacttcc tctttatttt tctacatctt caggaaaaac agaaaatagt gaagaagtat
    18121 tttctgcaaa atatccttat ttaaagtctg tggaaagtcc ttatgataag tattccccta
    18181 aatttgcgtc aacacttaaa ataagcaaca cagattttgt taaaagtctt agaagggcat
    18241 atagcactat tgtgatagat gtgaataatt taagtaaaca agtttcaata actaaaagaa
    18301 gtgatgccgg aactgtagaa aaaataaaat taggaaataa agaattgact ggaaaagaca
    18361 ttagaactgt ttttaaattg aactctgcaa actttgacat aaaatttgga gaaggataca
    18421 tagatttcgt ggtaaaagga tatggtcatg gtgttggtat gagccagtgg ggagcagaag
    18481 gaatggcaga agagggctat aaatattatg atatattatc acattactat acagatacaa
    18541 aaataaaaga tatatactaa taattgtata aaatgccaaa aacacgtcaa taatccaaat
    18601 gtagaaatat atttggaggt gcaaaatgaa gaaaaagctg ttagaaaaag atggttttta
    18661 tttatctttg tttgtatgtg tttgtttatt agcagtaggt ggagtttggt ttacaaataa
    18721 taatgtagat aaattggctt ctaataaagg aattatggaa aatgctaata aagatagtga
    18781 agaggaaata catttaattg aaaaagacaa gaaagatgct atccctactg caacggattc
    18841 aaaacaaaac ttagaaaaag ctaagtcaaa agaggaaaat aaatcgagta caacaaaatt
    18901 aaattacatt ggagataaag taataagagg atattcagaa aaagaaccta gttattctaa
    18961 aacacttgat gtttgggaaa ctcataaagg tgtagatatt agttgtacta aaggcaaaga
    19021 agtaaaatct ctattaaacg gaatagtagt agatgtattt aatgatgaag aatatgggca
    19081 atcagtcaaa ataaaaagtg acaataacat tgtagtagta tattcaaatc tagataaaaa
    19141 tgttagtgtt aagaaagaac agaaggtaac agaaggacaa tctctaggta ctgtaggtag
    19201 tacttctcaa atagaaagtg aagaaggtat acatgttcat ttagaggcgt atagtggaga
    19261 aaaatctata gacccaatga gtctaattaa gtaaaagtat aacaagttta atcatatttg
    19321 gttaagcttg ttatattttt tggtgttttt acatatatat cattaaagct attatgtgag
    19381 gggggtaatc tttgagatct catatagagg aaagggccat agtggtagca aaatatatac
    19441 ttgaaaaaaa cactacagta agacaaaccg ccaagacatt tggagtaagt aaaagtacaa
    19501 ttcataagga tgttacagaa agattgaagg aaataaatcc atcccttgcc aaagaagtta
    19561 aaaatgtgct ggacaaaaat aaatcagaga gacatattag agggggatta gcaacgaaat
    19621 taaaatatga gaaggaacat aaaaaaatgt aggttaaaaa cctacttttt ttatttaatt
    19681 aaattataaa aagaaatata ttaagtaatt ataaatagca aaataataat actctcaaaa
    19741 gatttatttt ctcttgatta aagcgagatt tttgtatatg ctttattata ggagtattaa
    19801 aataggctta taatataatc taatattata aataaaggag ttgaaaaaat ggctggagct
    19861 gatataggca tagatttagg tactgcaaat gtgcttgttt atgttagtgg taagggaatc
    19921 gttttagaag aaccgtctgt tgtggcgata gacaacagaa cagattctgt tttagctgtg
    19981 ggagaagaag ctaaaaagat gatagggaga acaccaggta atatagtcgc tataagacct
    20041 ttaagagatg gtgtaatttc agattatgat gtaactgaga agatgttaaa atcttttata
    20101 gataagatag ttgataaaaa gggatttgga agatttttta tgccaagaat tatggtatgc
    20161 gtaccaacag gtgtcacaga agtggaaaag agagcagtag aagatgctac gagacaagct
    20221 ggagctagag aagtatatat aatagaagaa ccaatagcag cagccatagg agctggtgta
    20281 gacatatcac agcctaatgg taatatgatt atagatattg gtggaggtac tgtagatata
    20341 gctgtaatat ctctaggagg agctgttgta agtgaatcta taaaggttgg tggagataga
    20401 tttgatgatg ctatagttaa atatatgaaa aaacaacaca atcttcttat aggagaaaga
    20461 acagcagaga aaatcaagtt tgaaataggt tctgcattta agagagaaga agaaaaatat
    20521 atgaagataa caggaagaaa tttaattaca ggacttccta gttctataac tataaattca
    20581 acagaaatgt tggaagcact tagagaatgt gttgagcaaa tagtagttgc tactcatgct
    20641 gttttggaaa aaacgcctcc tgagttagca gcagatatag gagatgttgg tataataatg
    20701 actggaggag gttcattatt atatggatta gataaaataa tagaacagag aacaggaata
    20761 actgttacaa tagcagatga accattatct tgtgttgcaa aaggtacagg aatagcttta
    20821 ggttcaatag acctacttga aactggcggg tctttcaaaa gaaaataatt aggagagttt
    20881 agaatgttaa atatagatga aataaaaaaa ttaataccac atagatatcc ttttttatta
    20941 gtggacaaga ttacagagct agaagttggg aaaagagctg ttggtataaa gaatgtaaca
    21001 gttaatgaac catttttcca aggtcacttt ccagaatatc ctttaatgcc aggagtatta
    21061 atagtagaag ctttagcaca agtgtgtgga gtggcaatga tgtctgtaga ggaaaacaaa
    21121 ggaaaactag gtgtatttgc aggtatagat aaagttagaa tcaagagaga agtaagacca
    21181 ggagatacat taactatgga agttgaaatg acaactctta gaagaaatat agccaaggca
    21241 gatgctaagg catatgttgg tgaagaactt gtctgtaaag gggaattaat gtttgcctta
    21301 gtagaaaaat aaaaacttga aatataaaag taaaaaggta gataatttgg agtatttaat
    21361 cagatactct aaaatatcta cctttttata taaagaattt tatcatttag tttatattta
    21421 gattaggtgg atactaataa agccaaggct attgtttcag ctaagtctaa tataaagcta
    21481 agacgtatat tattaaatga aagtttatta ttttcatcaa ttttatctac aattcctact
    21541 atagaataat ttcctatttg aggtagtttt ttgccaacac cttttccggg caggataggt
    21601 ccttctctaa tctgtatatt acctatgtta ctctgcgacc ccaagcaagc atctatagcc
    21661 aagaagttac cttgtatatg tgtatttttt atagtatcta aagactcata tatatttaag
    21721 gcgtgaatag ggttatctag tgtaccgtaa acggggtatt taaagttact gttcttaagt
    21781 attgttccaa ctaaagggcc taaagtatca cctatagccc tgtctgttcc tatgcaaaca
    21841 acaatcgtat tttcattaat tatagttttt agaactgaac ttagcatctg tataacatca
    21901 tcatcgctgt aatttacttt agctaaatac aataggaaca cccccttcaa aaaaatatat
    21961 gaataaaaag cattaaaaag acctaacttt aaatttcaga tagatagaaa attttatttg
    22021 tcttacaaaa aaaggaatag aaaaaatatg actaaaaata ttgacaaaat tttaaaaaaa
    22081 tagtaagcta gtaaagtaaa acaaaactta aatcttgatt accttatcaa gagaggctga
    22141 gggataggcc ctgtgaagcc cagcaaccac ccaaatggga aaaggtgcta attcctacaa
    22201 gacaaaagtc ttgaaagatg aggtcagtta attagtatgt aattacgatt attaacctct
    22261 tcttataaag gagaggtttt ttattttgag taaatttcta aaattaaaaa taaggtaaaa
    22321 cctataataa aaactaagaa taaataaggg ggaataaaaa tggcaagaca tttatttacg
    22381 tcagaatcag ttacagaagg acatcctgat aagatatgtg accaaatatc agattcaata
    22441 ttagatgcat tattagaaaa agacccacaa tctagagtag cttgtgaaac tacagttact
    22501 actggtttag ttttagtagc aggagaaata agtacatctg cttatgtaga cattcctaaa
    22561 ttagtaagag aaacagtaag agaaattgga tatacaagag caaaatatgg atttgattgt
    22621 gatacttgcg cagttataac ttctattgat gaacaatctg gagatatagc tatgggagtt
    22681 gatgaaggcc tagaaagtaa gactggagaa gagatagaag aagaaataga aaaagttgga
    22741 gctggagacc aaggtataat gtttggattt gcatgtaatg agactccaga attaatgcct
    22801 cttccaatat ctttggcaca caaattatca agaagactta cagaggttag aaagactggt
    22861 ctagttgatt atttaagacc agatggaaaa actcaagtta ctgttgaata tgaaggaagt
    22921 aaagctgtaa gagtacatac agttcttata tcagctcaac attgtgaaac agtatcaaat
    22981 gataaaataa gagaagattt aattaatcat gttattaaag aagttatacc agcagaatta
    23041 cttgatgaag atactaaaat ttatataaat ccaacaggaa gattcgttat aggaggacca
    23101 caaggagata caggtcttac aggaagaaaa ataataatag atacttatgg tggatattct
    23161 agacatggtg gaggagcttt ctcaggaaaa gaccctacaa aggttgatag atctgctgct
    23221 tatgcagcta gatatgttgc aaaaaatatt gttgcggctg gtcttgcaga caaatgtgag
    23281 atagaacttg catatgctat aggtatagct agaccattat ctatatttat agatactttt
    23341 gggacaggca aagtttcaga agaaaaactt gttgaattag taaataaaca ctttgattta
    23401 agaccaggag ccataataag agacttagat ttaagaaagc ctctttataa aaaggttgct
    23461 gcttatggtc actttggtag aactgatata gatttacctt gggaaagaac tgacaaggtt
    23521 gagcagttaa gaaaagatgc tttaggtgaa taatttttaa ctaaaaagct gttagaatgt
    23581 aattttacga ttactttcta acagcttttt tattatgagt taaatatttt taataaatgt
    23641 taatttatca tcatataatg aataaacagt atttaatctg gtcaatacat tttatataat
    23701 actatactaa atttatgcat attatgggat atatgttaaa ggatggttaa gaatgtgtta
    23761 actaatgtta aataattaaa aatatattga aatatcataa taatgagtct aatataatct
    23821 taataaactt acactttaaa aataatttta attgggggga gtagtgtatg tcaggcaaag
    23881 taaatattaa aacggttata agttttgctg gagcttatgt tgctactgta ataggttctg
    23941 gatttgcaac tggtcaagaa atactgcaat tttttacatt ttatggatat gctggtatta
    24001 taggtggaat aatctctatg gtactatttt catggtttgg agcagaggtt atagataagg
    24061 gaagagaatt gaaacttaag gagccaataa aaatttatca agtatattgt ggaaaatatc
    24121 ttggaacatt ttttgaatgg tttggtccat tgtttttatt tggaacatta gtaataatga
    24181 ttgcaggagc aggagctaca ttatcagagt actatggatt aaatccatat gtaggtagga
    24241 ttggtatgac aatcgtttcc ctaataactg tttcattagg tttgacaagg ctttctaaaa
    24301 tactaggtaa tataggacct ataataataa tatttacact tttagtagga gcaattagtt
    24361 tatttagcaa tattgatgct ttatcaaatg ctggaaatat ggttgatagt ttaaatatta
    24421 aaactgctac atcaaatgga tatttctcag gagtacttta tacttgttat aatgtaataa
    24481 tagtaataac attcttgaca ggaatgggag cttctgcagt aaataagaaa gatgctgtgt
    24541 ggggtggtat agtaggtgga gtagcactta tggcagcagc tataatgatg aatttggcat
    24601 tactttcaga cataggaaat atatacacaa aagagatacc agcactttac ttagctgata
    24661 agatatctcc aataataggt attttattct cagtagtact tttactagga atatacacta
    24721 cagctgtacc attgttatgg tcagtaacta accgatttgt agaagatgac caccctaaat
    24781 ttaaaattat aacaatagta gtaagtatat tagcttgtat aggaggtcta ctgccatttg
    24841 ataagttagt aggtacacta tatccatata caggttacat gggaatttta attttactat
    24901 gtatgcttta tagaagaatt actaaaactg aggggtacaa ggagaataaa tctgaaataa
    24961 gctagtactg taatatactt atgaaattta atttatactc taaatatgga gtaattaaaa
    25021 taaaatagct atttaaatat ggtacctgta tttcatggta ccatatttta tggatgcaga
    25081 ttttttttgt ttctgataaa atgtataata gttggaaatt acgttaagta taaaaatata
    25141 aaacttttct acgattatca tagttttaat atataaaatt atactaacat ttaaatggag
    25201 cgattattag tatttttagg agataaaaat ggaaaaatta gaaggaatga taagtgaaat
    25261 agtctttaaa aacgaagata atggttatac aatagctcat ctggtaaatg aaaatgatga
    25321 aattgtcgtt gtaggatgta tgcctacttt ggcaattgga gaaagcatag aagttgaagg
    25381 aaagtgggta aaccataaga tttatgggac tcaatttgaa gtgaatagtt ttatgccagt
    25441 aacaccatca tccttagaag gaatttatgt ttacttatct tctggaatga tacatggtat
    25501 tggtgaaaaa atggctaaaa gaataattga taagtttggt gtagatacgt tagaggtgat
    25561 acaaaattca ccagaaaaac tacaagaagt agaaggtata gggagtaaaa aagtaaaaca
    25621 aatagtaaaa agttatgaag aagacagaga attgagaaat ataataatac agctatctcc
    25681 ttttggaata acaccaaatt actgcctaaa aatatataaa aaatataaaa gcagtgcaat
    25741 agaagttata aataaaaacc cataccaact tgctgaagat ataagaggaa ttggatttaa
    25801 agtagctgat agtatagcaa ataaaattgg tatagataaa aattctaagg atagaatttg
    25861 tcagggaatc ttatacactt taaataaatc tttaagtaat gggcatacat atttaccaga
    25921 gcatgttcta atacaagatt cggaaaaatt attggagcta aatggagaaa taataaaaga
    25981 gtgtgtaatg atgctagttt ataatcaaaa aatacatgta gagaaagtaa acaatgaaaa
    26041 tcttatatac cttatgccat actatttagc tgaaaatgga gtatgtagtc aaatagtaaa
    26101 attatcacag tatgaatttg aagacttaaa aatagatata gataacgaga ttaatgtttt
    26161 agaagaagat aagaaaatta agttagcaga aaaacaaatt ttagcagtca aagaatctgt
    26221 taatagtggc gtattaatta taaccggtgg tccaggaact ggtaaaacaa ctaccattaa
    26281 tgctatcata gatatatttg aaaataatgg taaaagcgtg actttggcag ctccaacggg
    26341 aagagcagca aagagaatga gtgaaacttc taataaagaa gcaaaaacta tacataggtt
    26401 gctagaaatg ggattttcaa cagatgatga tttaactttt tttaaggatg aagaagaccc
    26461 aataaattca gatgtaataa ttgttgatga ggtatcaatg gtagacatta tcttaatgta
    26521 caatttactt agagctataa agttaggaac aagagtaatt ttagttggag atagtgacca
    26581 attaccttct gtaggtgctg gaaatgtact taaggatatg attaattcta atattataaa
    26641 tgtagttaaa ttaaatgaaa tatttagaca agcgcaagaa agtatgataa ttgtaaatgc
    26701 ccataagata aacaatggag aaccacttta tctaaataca aaaggtaaag atttcttttt
    26761 tataagaaaa tcaactaatg aagaaatttt aaatgaaata ataggattgg ttaatgaaag
    26821 attacctaaa ttttataaag ttgataaatt aaaagatata caagttttat cctcaatgag
    26881 aaaaggtgaa ttgggagtta ctaatctcaa tatagagtta cagaagtatc ttaacaaaaa
    26941 agaaaaattt aaagttgaag aaagtttttc taaaagatta tttagagttg gcgataaggt
    27001 aatgcaagta aaaaataatt atacaaaaaa atgggaaaca gaagaccaaa aagaaagtgg
    27061 agaaggtatc tataatggag atataggata tgtttatcac atagataaag ataaaaaaac
    27121 tatttatata ttatttgacc agactaaaat tgtatcatac ctatatgatg aattagatga
    27181 aattgaccat agtttttgta caacaataca taaaagccaa ggaagtgaat ttccagttgt
    27241 agtattgcca atagcttggg ctcctcctat gttacttagc cgtaatttat tatatacagc
    27301 agtaacaaga gcaaaaaaat tagttgtatt agttggagat gtgaaatatc ttgaatatat
    27361 gataaaaaat aatagagtta atcaaaggta ttcaaattta ggatataagc taaataaatt
    27421 taagcaagaa gggctgttga tagaataaat atgaaaatat gcaatgataa ttttattaag
    27481 aattttaaaa atatgattaa taaatgtttg gattttatat atcctgagaa tataagttgc
    27541 ataatttgtg ataaatccat aaagaaaaca aatacttatt caatatgtaa aagttgtttt
    27601 aaagaaatga attttataca agatggttgc atgaagtgtg gaaaaccaat aatacgtcat
    27661 tcaattgaaa aagaatttat tgaagaatgt agttattgtt ttaataaaga cttttatttt
    27721 gataaatcaa tatcttgtat tgaatacaat gatgtgacaa aaaagatagt gctagggctg
    27781 aagtataacc aaaaaacctt tatggctaag tatatagctc aaataatgaa agaaaaatta
    27841 tatttagaaa acataaaatt tgattatata ttatttgttc cacttcataa aaaaaggcta
    27901 aataaaagag gttttaatca ggcacaaaaa atagcattta atttaagtaa aatagtaaat
    27961 attccattat tggattgtat aagtagaaaa aaatatacaa gaatgctata taaattgaat
    28021 aagaaagaac gaaaagaaga attaaaaaat gtatttgttg ttaaagacaa tgttaaatta
    28081 ataaataata aaaatatact tttaatagat gatatattta ctactggtct aacaacaaac
    28141 gaaatttcta aacttttaaa gttatcgggt gctaataagg tttttgtatt gactctactt
    28201 acaaaagcaa atgataatta tattatggaa taatcttata tattgacaat tttaatttaa
    28261 aatattaaaa tgaataagtg atatttaggt ctgtggttga aagtccaagc cagtcgcagg
    28321 caaagggatc cacgtaagtt aacactaaaa attgggttaa tgatcatggt gcggcttaga
    28381 agtaagacct accgataata aaatcgagag agagtagtag tgcggcgaac ccaagcgaac
    28441 cctccagtag gcgagtgtgg ggtcaaaaac caggtcagct aaatatcgta ttaaaaggga
    28501 gctagcatac ctttatgtat agctcttttt tatatataat aaatttaggt tgagtcataa
    28561 agaggtgata tgtttgaata aaagacagga aaacttatta acaacgttgc tattaaaaga
    28621 agagtttata aatgttaata agattgccaa tgattttgag tgttcagaaa ggacaataag
    28681 aaatgattgc aaatatattg atgaatggtt atctactttt tgtaatgctt atatcaaaag
    28741 aaaacctaat attggaatta aatttagtgg agatggaaca gacaaaatac tggtaaatca
    28801 gaagttgcga ggtgaagtta aaagagtaaa tagtgagctt cataagcaag ttgagatatt
    28861 aaatttacta ctttgtaata ataaaaaagt tactttaaat gatttatcta ataagttgta
    28921 cataaataaa aatattgtca gagaagaaat aagtaaatta tcagtggcat taaataatta
    28981 taatttaaat gtctcgacta aaaaaggcag tggtatatat attggagggg atgagaaaga
    29041 cataagaata atgttagtat cattcttatt taaatacata gataaataca gattaaacat
    29101 agatgaaata gagtacttcc atatagtaga tataataatt gtaaaaaaca taatgtttac
    29161 tatagaggag gatatggata taagacttac agatatatca ttcaagcaat tgatgctatt
    29221 tttacttata aatataatac gaataaggct aggaaattct ttaaaagtat caaatactaa
    29281 gaaagagctt aagctaaaaa tgctgatatt agatatagaa gatgaattga aatctaattt
    29341 atccatagta ttaaattatg aagaaaaatt gtttatagag tctttaatat tgggtatgaa
    29401 caaacaaata aatagtagta atattaagaa atctttatat ctaaatgaag aattagcaag
    29461 ttatacaaaa aaaattataa atttagtatc agaagaatcc ggaataaatt ttaataatga
    29521 tatattactt tatgaacaat taatatgtca tttgaatgtt acaatgcacc aaatgaaaag
    29581 caatgtttac ttagaaaatc cacttttaga taacataaaa actaaatttt gttttttatt
    29641 tacagtaata tcaagttcaa tagaaattga attaaaagga aaacaaataa cagaagatga
    29701 aattggttat cttacacttc actttcaaac ctctctagaa agaaaataca gcaaaaggga
    29761 atcaaataaa aaggcaagta ttgtatgtcc atttagtttt ggagtaagca tgctattaaa
    29821 agtaaagata gaaaagagat ttgataacat aaaaattatt gaaacattaa gagaggaaga
    29881 tttaaaaaga gataacttca ataagactat agattttata attgcatttc aagagtatga
    29941 aaatatccaa aaaccaattt ttataacaac accattattt actgatgagg atgagaataa
    30001 acttaaagag ttcacaaaca aaataaaaga aaaagacact tcatataaac ttatgaacag
    30061 attaatgatg tctgattatt taataagaga gttagaacat gatgatattt atgaagctat
    30121 aacatattta actaatttat taattgaaaa acattatgca gaaaaagagt atttacaatc
    30181 tattataaca agagaaaagt catatccaac caatgttgga aaaggaatat tattccctca
    30241 tggagatatg aaatatataa aacaatctgt tttatgtttt gcaaggttaa aaacaccaat
    30301 aagaattaga aatggaaagg atataaagat tatacttttg ttagcatata aaaaagatga
    30361 tgatagaaaa gtatttagag aattatttaa agaaatatct aatttaacag aggatgaaaa
    30421 tatgctagat attctaagta aatgtgacat tgaaaaagta aaagatattc ttatataaaa
    30481 ttcatagtga actatggata agcacaaaat tttccatgtg atggaaaaag ttgtgcatgt
    30541 ttttttgttt ttataagata ttatatgttt gtaaggtata aataatctaa aagtagagaa
    30601 gcaacttagg aggaaaaaat ggaagaaata gttttaaaga ttataattca tgctggaaat
    30661 gcaaaatcta tgctttatga agcacttgac tatgcaaagg aaaacgattt taaaaaagca
    30721 gatgaattaa ttgaaaatgc aaatgaagaa attttaaaag cacataaagt acaaactgaa
    30781 cttatacaaa aggaagctgg gggagataaa tcagatatat ctattttatt gattcactct
    30841 caagaccatt tgatgacttg tatgagtgag agaaacctta taaaagaaat gattatgtta
    30901 agaaaagaaa ttcaaaaatt aaaataaaaa aattaagggg gatttaaaaa atgaaaagaa
    30961 aagtatattt attttgtagc tttggtatgt caacaagttt acttgcagat aaaatgcaga
    31021 aggtagcaga tgaacacaat ttaccaatag aagtagaggc atttccgata gcagaaattg
    31081 acaaaatagt tgaagaaaaa aatccagatt gtatattact aggaccacaa gttaaataca
    31141 tgctaaagga attaaaacca aagtttgaag ctcaaggaaa acttatagat ataatcaatg
    31201 aagttgatta tggaactatg aatggggaaa aagtattaaa actcgctata aagctaataa
    31261 aatccaaaca agcgtagaat tatagtaaaa aataatagga aatgagggta gatagatgaa
    31321 tagattggaa agaatactta tgccattggc tgaaaaaata ggtaaaaata aattattaat
    31381 tgcaattaga gatggttttt taatatcatc accattatta ataataggtt cattattttt
    31441 attagtagca aattttccta taaaaggatg gaatgaattt gtaggtcaaa tttttggttc
    31501 agattgggct gtaaaattgc aacaaccaac tgtagcaaca tttgaagtaa tgactctact
    31561 tgcagtttta ggaattggat attcttatgc aaagcaaata gatgtagacc caatagcatc
    31621 agcagcagtt gcaatagttg ccttttttat aataacacca tttgtaatac catatacacc
    31681 agaaggaaca gaatcagtct acatggtaac aggtatacca ctaggttgga tgggctctaa
    31741 gggaatgttt gtaggtatga taacagcaat aacctctgta aaattatttg ctgcagttgt
    31801 aaaaaaagga tggacattga aaatgccaga tggagttcct ccaaccgtat caaaatcatt
    31861 tgcagcatta ataccaagtg caatagttat ggtagttttc tttttagtta agatagcttt
    31921 tgaagctaca ccatatggaa gtatacatga atttatattt aagtttttac aaatgccatt
    31981 attaaaatta ggaaatagtt taggtgctat ggcaatcgct tatatattct tacatttatt
    32041 ctggttcttt ggaataaatg gaagtagtgt tgttggggct gtgtataatc caatattaaa
    32101 aattctatca gctgaaaatt tagctgcttt tcaagctggt tcaaaaatac caaacataat
    32161 aacaggtcaa ttccaagata tgtttgcgac atttggtgga gcaggtagta cactatcatt
    32221 agtcatagct atgttattaa tatgtaaaag taaacgtata aagtcaatgg gaaaactatc
    32281 aattttacca ggaatatttg gtataaatga gccattgata tttggtctac caataatgct
    32341 taacccaata ctattgatac catttgcaat agttccaaca ataaatataa taatagctta
    32401 tttctgtatg tcagcaggat tagtgcctct tacaaatgga gttcagttac cgtggacaac
    32461 tccaattata ttctctggtt ttttaacaac aggatggcaa ggtgcagtct tacaagtagt
    32521 gcttcttata ctaggaatat ttatgtatat accatttata aaaatgctag ataagcaata
    32581 cttaagagaa gaaaatgcaa ctgttgaaga ggaagatgat gatatatctt ttgatgattt
    32641 agtattatag gaggaagatg atgaagaaaa tagttatgat attggatcaa atacaagctg
    32701 gagctggagg aaaagagaaa agtaatatac ctcctgctgg aaaatcaagc ccattaggac
    32761 caggtataat gatggagcaa tttttaaatg aatctaaggt aatagctacc ttattttgtg
    32821 gggatgaatt ttttgtaaat aatgaagaag aagtaactag taagatgata gctatggtaa
    32881 aaaaattaaa ccctgatgta gtaatctgtg gaccaagctt taattacgaa aacttttcta
    32941 agatgtcagc aatactgtct aaaaatataa atgataaaac agatatacca gcttttgcag
    33001 ctatgtcaga agaaaatata gatgtgataa acgaatataa aaatgacata tgtatagtta
    33061 agactccaaa aaaaggtgga attggtctta atgattcatt aaataacata tgtaaattgg
    33121 caaaagcaat agcaaataaa gaagatataa ctttgatgaa agaagaattt tgttattaat
    33181 aagagtatta attattagta agtttaaata ttatactatt tataataagc atacattagt
    33241 aaaatctata taatttaagg aggggaattt taacatgtgg ggaatgatag cgacatggag
    33301 aatggcccta gaaggaataa ctgaggcatc agaacattta gaaaaaggca tggaagcagg
    33361 tgatgctgta gagcttgctg taagaagagt tgaagactat ccattctata aatcggttgg
    33421 atatggtgga cttccaaatg aaaattgtga ggtagaactt gacgctgcat ttatggatgg
    33481 taacacatta gatattggag cagttgctgg tataagagat tattctaatc ctgtcagcat
    33541 agctaggaag ttaagttatg agaaggtaaa taatttttta gttggaatag gtgctgaaga
    33601 ttatgctcat aaaaatggat ttgaaagaaa aaatatgttg actgatagag cgaagttaca
    33661 ttataaaaag agaaaaaaag agactttaga caaaggatta agtccatatg ctggtcatga
    33721 tactgttggt atgatatctt tagacaaaac tggaaaaatg tgtgcagcta catcaacaag
    33781 tggattgttt atgaagaaaa gaggtagaat aggagattct gcactatctg gttcaggatt
    33841 ctatgttgat agtagtatag gaggagctac agctactggt ttgggagaag atttaatgaa
    33901 gggatgtata tcttatgaga tagttagact tatgaaagaa gggaagcatc cacaagaagc
    33961 atgtgatatt gcagtaaatg aacttgataa acagcttatc aaaagaaggg gaaaagctgg
    34021 tgatttatca ttagttgcca tgaataataa aggtgaatgg ggagtagcta caaatatagc
    34081 tgattttact ttttcagtag taactaaaga agaatctcct actgtatata tttcaaatag
    34141 agtagatgga aagactatac ataaggttat atcaaatgag tggatggaag catatgaggc
    34201 tagaataaaa gcaccaatag aagtaagtga gtaaagtagt ggttacataa ttaaaataga
    34261 gttttataat aaggagattt ttatgaatat cataagtaat aaaatagatg agttaaaaga
    34321 agatttatta agtgatatta tagatattgt aaaaatacct agtgtcaaag gggagtcaga
    34381 aaatggcttc ccttttggcg aaaaagtagg ggaggcactt aataaagcat tagaaatatc
    34441 agaaaaattg ggatttaagg ttagaaactt ggataattat attggttatg cagagcatgg
    34501 agatagtgat gattatgttt gtgtaattgg acatgtagat gttgtacatg aaggagatgg
    34561 ttggaagcat cagccttata agggagaaga aactaatgga agaatttatg gacgaggagt
    34621 actagacaat aaaggaccta taatgtctgc cttatatgga ttatatgcta ttaaagaatt
    34681 aaatttaaaa ttagataaga gagttagaat aatatttggt acaaatgaag aaagtggatt
    34741 tgaagatata ccatattatt tagaaaaaga aaaagcacct attatgggat ttacaccaga
    34801 ttgtaaatat cctgttgtat atggtgaaaa aggcatggca aagattagaa taaaaagtaa
    34861 aatcaattat gaagaagatg tatacttagg ttttatagaa aatatgtctg aaaatgtgct
    34921 tgttacatat aaagaactga atatagaaaa tagtgatact atattagata taaaggtaaa
    34981 atacgatttt agttataaat tgaaagatgt attggatgaa ataaaagcta gttttccaaa
    35041 tagtatcgat atagaggtaa tttctaattt taatcctgta tattttgata aagagagtaa
    35101 tcttgttaaa aagcttcagc tagcttatga aagggttaca tcattagatg gaactccagt
    35161 aacaactaat ggaggtacgt atgcaaaagt aatgccaaat atagttccgt ttggaccttc
    35221 atttccagga caaaaaggaa tagctcataa tcctgatgaa tacatggata tagaagatat
    35281 aatattaaat gcaaagatat ttgcaaatgc aatatatgaa ttagcaaagg agtagttatg
    35341 ttagaaataa taggaatgtc agtagaagac gctaaaatta tagaagattg tggtgcagat
    35401 agaatagagt tagttagtgc tttaactgaa ggtggattga caccaagttt tggtcttata
    35461 gaaagtgttg ttaacagtgt aaagatacct gtgaacgtaa tgataagaca tcatgcgaaa
    35521 agttttgtat acagtaaaga agatataagt ataatgcaaa aagatataag tgtggttaaa
    35581 gagattggtg ctaatggagt tgtatttggt gtattggata aaaacaatag tatagatgag
    35641 aaaaatctaa atgttttatt gaaatgttgt gataatcttg atgttacatt tcatagagca
    35701 atagatgaat caaatacaat agatagtgtt aaaattttga aggattatga taaaattacg
    35761 aatatattaa catcaggagg gaaaggaagt atagttgata acatacaaat gataaagaat
    35821 atgatgctta gttctaatca cataaaaatt cttttaggtg gaggtcttaa ttttaataat
    35881 atagaaaaga taaaggaatt aactaaggca agtaattttc attttggtac agcgattaga
    35941 ataaataaca gtccttttga agatatagat agacaaaagc ttaaacaact cgtaaatata
    36001 atttcaagat agtatatgaa tataaaatac ttagtttaaa taaagagagt aagttaatta
    36061 taatttgggt atatgaatgt taataggtat taaatatgaa attattgttg agtatgcttt
    36121 ataactttta agtagtttta aatataaata atgaaagaaa agatagatta tggaggtttt
    36181 agagggttta tatttattaa aaaattataa aggtatattg gcatataata cacataattt
    36241 cctaaaatta ccatcttatg acatgaattc acatattaat aaacaattaa tggagatttt
    36301 tgtggataga aataggagta aaaatagctt taaataaaca aaaacaagag ttattaacag
    36361 ttttatccac attatccaca ggtgtttgta ataatattaa tccacataag tatcaatgta
    36421 actaaaaatg ataaataatt ctatcaattg aatagaaaaa atcataaaag taaataataa
    36481 aaagaggatt atgagagttc gtgtagaata tattattaaa gtataaattt tcttatactg
    36541 gcataattga agggagatgt atttatgaac ataattatat ctggaaaaca aatcgaatta
    36601 actgatgcaa taaaaaataa aatcgaaact aaactaagta agttagataa ttacattcat
    36661 ccagacactg atgtaaaagt tacagtaagt gcgagaaaag caagacaaaa aatagaagta
    36721 acaatagcta ctgtaaatgg tcctataatt agagcagaag atatgcagga aaatttatac
    36781 acagctatag atgttgtata tgataaatta agtaaacaat taaaaaaata taaaaagaga
    36841 ttacaagata aacataaaga caacaagagt ataagattcc aagatgcaga gataaatcta
    36901 gctgatgaac aagaggatta tggggatgaa aatcaagaat tagtaattca aagacgtaag
    36961 aaatttagtg ttaagccaat gagtgaagaa gaagctgtat tacagatgga attaatagga
    37021 catgattttt atatgttcaa gaacatagat tcagatgaaa tagcagtagt ttataagcgt
    37081 aataatggtg gatatggtat aatagaacat gaataaagca atttagattt aatcatatta
    37141 gctatcgata aataaattat cgatagcttt ttaaattaat attaaaagta tagtttttat
    37201 ggtaaaatga ataatagtac aataaagaac gaggagagat gtaaaatatg agctttatgg
    37261 ataatttatt caacatggca gataaaaaag aattaaaaaa gttcaataaa actgttgata
    37321 taatagattc attagaacct aaatttgaat ctatggcaga ctcggaactt aaaaatatga
    37381 caaatatatt taaagaaaga ttagcaaatg gtgaaagtat agatgatata cttccagaag
    37441 cttttgcagt agttagagaa gtttctaaga gagtgttagg acttagacac tacagagttc
    37501 aaatgattgg aggtatagta ctacatcaag gaagaatagc agaaatgaaa acaggtgaag
    37561 gtaaaacttt ggttgcaact gctcctgttt atttgaatgc gcttactgga aaaggtgtac
    37621 atgttgtaac agtaaatgat taccttgcaa aacgtgatag agaccaaatg gcaaaaatct
    37681 atgagttttt aggaatgagt gtaggcgtta ttatacacgg tcaaaatcca aaagttagaa
    37741 aagaacaata tgattgtgat ataacttatg gtacaaataa tgaatatgga tttgactatc
    37801 taaaggacaa tatggtaata cacaaagagc aaagagttca aagaggatta aattatgcta
    37861 tagtggatga ggttgactct atactaatag atgaggctag aacaccactt atcatatctg
    37921 gacctggaga caaatcaact cacttatatt cagatgcaaa cacatttgtt ttaaccttaa
    37981 aaccagatga ttatgaatta gaagaaaaag ataaggctgt atctctaaca gcatcgggta
    38041 tacaaaaagc agaagtgtat tttaatgttg ataatataac agatatatct catacagaat
    38101 tataccatca tataaatcaa gctttaagag cacatgtaat aatgaagaaa gatgttgatt
    38161 atgttgctaa agatggagaa atagtaatag tagatgagtt cacaggtaga cttatgtttg
    38221 gtagaagata ttcagaaggt ttacatcaag caatagaggc taaagaaggt cttaaaatac
    38281 aaagagaatc taaaacacta gctactgtaa cattccaaaa ttattttaga atgtacaaaa
    38341 aactttctgg tatgactggt acagcaaaaa cagaagaaga agagtttaaa gcaatctaca
    38401 aaatggatgt tttccaagta cctactaata agcttatgat aagggaagac ttaccagatt
    38461 gtgtatacaa aagtgaaata ggtaaattta atgctgtagc acaagaaata attgaaaggc
    38521 acaaagtcaa tcaaccaata cttgtaggta cagtatcaat agaaaaatca gaattattat
    38581 cacaaatact aaagaaaaag ggcataaagc acgaggtatt aaatgctaag catcatgata
    38641 aagaggcaga aataatagca caagctggta gacttggagc tgttacaata gctactaata
    38701 tggctggtcg tggtacagat atagttctag gtggaaatcc agacttttta actaagagag
    38761 aaatgagaag aaatggattt aaagaagaaa tagtaaatag agtagatact ccaatagaag
    38821 gtatacctgt aaaaggtaat gaaattctat ttgaagctag agaagagtat gaaaaactat
    38881 ttgaaaagtt taagcaacaa acacaagaag aacaaaaaca agttgtagaa gcaggtggac
    38941 ttgctataat aggtacagaa agacacgaat ctcgaagaat agataaccag ttgagaggtc
    39001 gtgctggacg tcaaggtgac ccagggagtt caagattcta tataggtctt gatgatgacc
    39061 ttatgagatt gtttggtagt gatagaatat ctggtattgt agataaaata ggtcttgaag
    39121 aagatatgcc gatagaacat agaatattat ctaagtctat tgaaggagca caaaagaaag
    39181 tcgaaggtaa aaactttgga ataagaaagc atgtacttca atatgatgat gttatgaata
    39241 aacaaagaga aataatatat gcagagagaa aacgtgtatt agaaggtgaa gatttacaag
    39301 aacaaataca atcaatgact cattctataa tagaagaagc agttactctt tatacacaag
    39361 ataaaggatt tgatgaagaa ggatttaaag aacatatgta taatctgttc ttgccaaaag
    39421 gtagcataga aataccagaa atagaaaaac ttaatccagt tgaaataaca gaaaaagttt
    39481 atgaaatagc tatgaagata tatacttcaa aggaagaaca agttggctat gagagaatga
    39541 gagaagttga gagagtaatc ttacttcaag ctgttgataa ccattggata gaccatatag
    39601 atgctatgga ccaattacgc caaggtattg gtcttcgtgc tgtaggtcag caagacccag
    39661 ttattgctta taaaatggaa ggttttgata tgtttgatga aatgaataaa catatcaaag
    39721 aagatactgt aagatattta tttaatataa caatagaaac tccagtggaa agaaaagcag
    39781 ttgtagatgt tgaaaatcta tcttctccat cagatggaac acttccaaca agtaaaactg
    39841 ttaaaaaaga tgaaaaggtt ggaagaaatg acttatgccc ttgtggaagt ggtaaaaaat
    39901 ataaaaactg ttgtggaaga taatctcgga ggattaaatg ttaaagttac aagagtatag
    39961 acatagtatg gagcagatgg cttcaaattt agaagaattg agggtttctc tttgacatag
    40021 cttcattgat gaaaaatata caaattaatg aagaaaagat gaataaacaa gacttttgga
    40081 atgataatga agtcgctcaa agagtacttc aagaaaataa gtctttaaaa gagacattag
    40141 aagaatatga aagcttaaaa agcttactag aagatataga agtattaatt gaaataggtt
    40201 tagaagaaga tgatgattct gtagaaagag atatagaaaa gtccatagaa tcaatggaag
    40261 aaaaattatc tgaaatgaaa ataaagactc ttctaaatgg agagtatgat aaaaataatg
    40321 ctatattatc tataaatgcg ggtactggtg gcttagatgc tcaagattgg gctcaaatgc
    40381 ttttgagaat gtatataaga tggtcagaaa gtaagggtta taaagttaag ctcttagata
    40441 taatatcaga ccctgaagcg gggataaaaa cagctacaat tcttgtagaa ggaacaaatg
    40501 cttatgggta tttaaagagt gaaaaaggag ttcatagatt agtgagaata tctccatttg
    40561 acccatcagg aaaaagacat acttcatttg catctataga tgtaacacca gagttagatg
    40621 aaaatataga agtagaaatt aatccatcag atttaaagat agacacatat agagcttctg
    40681 gagctggagg gcaacatgta aatacaactg attcagcagt tagaataaca catatcccta
    40741 ctggtgtagt agttcagtgc caaaatgaaa ggtctcagca tctaaataag gacagagcta
    40801 tgagactttt aatggcaaaa ttgatagaat taaaagagtt agaacaaaag gaaaaaatag
    40861 aagatataca aggcaaatac tcacaaataa cttggggtag tcaaattagg tcatatgttt
    40921 ttcaaccata taaattggtt aaagaccata gaacaaatgc tgagtttgga aatgtagata
    40981 gtgtaatgaa tgggaatata gacttgttta ttaatgaata cttaaaaatg aataaaatag
    41041 tttaataaat atgcactgta attaagatat atgtataaga aggttagtgc ttaatatgca
    41101 cttacagcac ttaggctgag gacgataacc ctcagccttc gttctgtttt gttatactta
    41161 tgaaaaacta acattaggag tgaataaatt ggatataaat caaattttaa aaaaagagtt
    41221 taatcttaga gatgaacaaa taaataatac attaaaactt attgatgaag gaaatacaat
    41281 accatttata gctagatata gaaaagaaat gactggcgaa atgagtgatg ttacactaag
    41341 agaattttat gaaaagttaa tgtatttgag aaatcttcaa agtagaaaag atgatgtagt
    41401 tagactaata gatgaacaag gtaaattaac agatgaaata acacaaaata tagaaaaagc
    41461 aaaaacacta caagaagtag aagatatata tgctccatat aaacaaaaga aaagaactag
    41521 agcaacaata gcaaaagaaa aaggattaga aaaattagca ttgtcaatac tagagaataa
    41581 tttagataat atagaaatag aggcaaagaa ttatcttgat gaagagaaag aagttctttc
    41641 tattgaagat gctctaaaag gtgctagaga tataattgca gaactagtct cagatgatgc
    41701 taagattaga aagtatataa gagaattagc tttaagagaa ggtatgatag ttagtaaaag
    41761 tgccactgat gagaaatcgg tttatgacat gtattatgat tatagtgaag cagtaaaaag
    41821 tatgcctcca catagagttt tggcaataaa cagaggagaa aaagaaaact tcctaaaggt
    41881 taagttagaa ataaataatg ataaagtttt aaattacata ataaacgaat atgtaaatga
    41941 taaaaatttc aaaaataaag aagaaatcgt aagttcaata gaagattctt ataaaagatt
    42001 aattttccca tcaatagaaa gagaaataag aaatcattta acagaaatag ctcaagaaag
    42061 agctataagt gtatttggaa agaatgttaa aagtttattg cttcaaccac cagttaaaga
    42121 caaagtagtt atgggatttg accctgcatt tagaactgga tgtaaaatag ctgtagtaga
    42181 taaaaatggt aaactactag attatacaac agtatatcca acagaccctc aaaatgatgt
    42241 agagggagca aagaaagttt taaaaggatt gattgaaaaa tacgatatag atataatttc
    42301 aattggaaat ggtactgcat ctagagaatc agaaactttt gtatcagaaa tgataaaaga
    42361 aatagataac gaagtgcagt atgtgatagt tagtgaagca ggagcatctg tttattcagc
    42421 ctctgaactt gcaaatgagg aacatccaga tataaatgta tcaataagag gagctatatc
    42481 tatagctaga agattacaag acccattagc agagcttgta aaaatagacc ctaaaagtat
    42541 tggcgttggt caatatcagc atgatttaaa caaaaagaga ttagaagaag tactagatgg
    42601 agttgttgaa gattctgtaa atagtgttgg agtagattta aatactgcat catactccct
    42661 actagaacat gttgcaggaa taagtaaaac tatagcaaaa aatataatag catatagaga
    42721 agaaaatgga gattttacgt caagagcaca attgaaaaaa gtaaagagac taggaccaca
    42781 agcatttact caatgtgctg gatttatgag aatcttagag ggtaaaaatc cactagataa
    42841 tacaggtgtg catcctgaaa gttatgatat atgtaaaaaa atgattgaga taattggata
    42901 ttctttagat gatgtaaaga ataagaatat atgtgaaata gatgaaaaaa taaaagaaat
    42961 tggcttgaga gaattaagtg aaaaactgga agtagggcaa gttacgttaa aagatatcat
    43021 aactgaaatc aaaaaaccag gaagagaccc aagagaagaa ggtataaaac ctatacttag
    43081 aactgatgtc ttaaaaattg aagatataca agagggtatg actttaaaag gtacaataag
    43141 aaatgttgta gattttggtg catttgtaga tattggaata aaaaatgacg gattagttca
    43201 taaatcagaa atgagtaata gttttgtgaa agaccctatg agtattgtta cagtaggtga
    43261 tatagtagat gtaaaagtca ttggaattga cttaaacaaa aaaagagttg ccttatcaat
    43321 gaaaaaatag ataagtttat gtatggttat agtacttaaa ttctatgttt gtaaatgagg
    43381 ttactcgagt gtataaatgt taaaaatttg taaaagtata cagtaagaaa atatattaaa
    43441 ataagaacga tagtcttgaa aatcaggagg aaaatgaatg atttttataa aaaatggtaa
    43501 aataaatacc ataacaaatg ggataattca tggagatata cttatagatg aaggaaaaat
    43561 aatagaaatt ggagaagatt tgatagctcc tttagatgta gaggtaatag atgctagtaa
    43621 taaacttgtg tttcctggat ttatagatgc tcatactcat ttaggtttgt gggaagatgg
    43681 tatagggttt gaaggagcag atggaaatga agagactgac ccaataacac cacaattaaa
    43741 tcccatagat ggaattaatc caatggatag aacttttaaa gaagcttttg aaggtggaat
    43801 aacttctgtt tgtacaaccc ctggaagtgc aaatgttatg ggtggtcaat gtatagctat
    43861 aaagacatgt ggaaaaagaa ttgataaaat ggtaataaaa aatccagttg catctaaaat
    43921 cgcttttgga gaaaatccaa agagctgtta tggtcaggat gataaatctc ctcaaactag
    43981 aatggctata gctgctttac ttagagaaaa cctaaaaaaa gcagaagaat atttagagga
    44041 tattgatatg tatgagagtc atgatgatga agactgtgaa aaacctgaat atgatataaa
    44101 aatggaaagt ttaataccag ttttaagaag agaaattcct tttaaggcac atgctcatag
    44161 agcagatgat atgtttacag caataagaat tgcaaaagaa tttaatttaa agcttacatt
    44221 agaccattgt acagaaggtc atcttattgt agatgaatta gtggaagaag ggtttcctgt
    44281 aatagtaggg ccatctttgt cagaaaggtc taaatttgag cttagaaatt tgacatttaa
    44341 tacagcagga atactttcaa atgcaggtct tgatgtatgt ataatgacag accatccagt
    44401 aataccagtt caatatcttc caatatgtgc aggtattgca gtcaaacatg gtatgaaaga
    44461 agaaaaagca atagaatcaa ttacgataaa tccagctaag actttaggaa tagaagatag
    44521 agtaggctct atagaagttg gtaaagatgc agacctagta atttgggata attctccact
    44581 agagattcaa agtaatgtac tttacactat aataaatggc aaagtagtgt atgagaaaaa
    44641 ataacttgac aattattaaa aaattaacta atataagagt gtaaggaaaa ttaaaaaatc
    44701 aaagaagatc ttcggggcag ggcgaaattc cctaccggcg gtatagcccg cgaactactt
    44761 aagtggttga tttggtgaga ttccaaagcc gacagtaaag tctggatgag agaagatatt
    44821 tatggaagat aaataagttt attttagttt gtttaaacta tatccataaa aactcgaaga
    44881 tagggtcttc gagttttttg tttttcctaa aaaatataaa catattgatt agggggaaat
    44941 aattatgcaa aacacagcca aaagaggcaa tatgatttca acaagaactt tagtagtaat
    45001 gtcaatttta tctgcaatat cttatttatt aatgtttatt caagcaccaa taccaggtat
    45061 atttccagat ttcttaaaaa ttgacttatc agatattcca gcaatattcg gaggaatgtc
    45121 tctaggacca tttgttggat ttggaatagt tgtagtaaaa aatgtgttac aagcaataac
    45181 agcaacaaca actggaggaa taggagaatt tgcaaatata ttaattggtg gttcttatgt
    45241 aatgatactt tgttattcat ataagagaag tggagattta aaaggtgtat tgattggttt
    45301 tgtattagga acaatatcta tgactataat tggttcatta gtaaattatt ttgtaatgtt
    45361 gccactttat ggtcaactta tgggactaga tgctataata ggtttaggtt cagctataaa
    45421 tcctcaagtt catgatttat tcacttttgt aatttggatg atagctccat ttaatgtgct
    45481 gaaggctgtt atactatctt tagtaacatt gccactttat aaaaaaatgg gaaatgtaat
    45541 aaagaaataa ttagacaaga aaatataaaa ttaaatgtat tgaatagcca taatttattt
    45601 ataacttcag tcctatattg tgattgatat attaaatata ttatggcttt attaatttat
    45661 caaaaaatgt atataaaata agaaatattt agacaaattt aaattttaaa ataaaggaag
    45721 aattaaaacg attaactatt aaaatatgaa aaaggtatct gcaatataca gagcgaattt
    45781 ataataaata aaaaataaag ttattattaa aaaaatataa agattagtaa tcaaat
//
LOCUS       DAMJVG010000026        45574 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.026, whole genome shotgun sequence.
ACCESSION   DAMJVG010000026 DAMJVG010000000
VERSION     DAMJVG010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 45574)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45574)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45574
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.026"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            162..821
                     /gene="cprR"
                     /locus_tag="PC512_001554"
     CDS             162..821
                     /gene="cprR"
                     /locus_tag="PC512_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CprR"
                     /protein_id="HDF2441300.1"
                     /translation="MSKILVVDDELDMLKLIENVLKRDGHEVKVISDVEKAMNMDFNY
                     FNLIILDVMMPKMDGFEVCKTIRNKVDCPILFLTAKNMESDIMYGLGIGADDYITKPF
                     GVGELRARITAHLRRESREKKNLLTISNVQFNFLGKEVSIDGKKINFTKSEYLICEFL
                     AKNKGQVFSKERIYESVYGFDGESDISTITEHIKNIRSKLKQYDIYTIETVWGIGYKW
                     V"
     gene            1032..2090
                     /locus_tag="PC512_001555"
     CDS             1032..2090
                     /locus_tag="PC512_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HDF2441301.1"
                     /translation="MDRLKNIRKSLLQYTFLFLLIGITIYLVFKTLDIKMLSNVMVMV
                     DKKFLFIGALAIMCHIMLEGVVMKIIIESTHKVNIRFIGFKLAIMGFYYNLITPFASG
                     SQPVQIYVLKKCKMPLSKASAVVTNKSIIFQIVVTFYCTILVLMNFAMLEKQMKMIMP
                     LVFLGIAINSFVLIMIILVILNPKKIKYFMRITIKHLSKIKFLKFLDNKIESIESFID
                     DYSKAINFFAKNKKVLISTIIVTFIQLSAYFSVSFWIYKAFNLQGYSYIYILTLQAFL
                     YMAISPIPTPGNVGANELAFFTIFKSVFPQPLMGYAVFLYGGFMYYLILIGSGIFTVI
                     THYRMKNRIGRNIVLSEN"
     gene            2341..4485
                     /locus_tag="PC512_001556"
     CDS             2341..4485
                     /locus_tag="PC512_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:2755..2757,aa:Sec)
                     /transl_table=11
                     /product="formate dehydrogenase H subunit alpha,
                     selenocysteine-containing"
                     /protein_id="HDF2441302.1"
                     /translation="MEKKILTVCPYCGAGCQLYLVVKDNKILRAEPANGRTNQESLCL
                     KGRYGWDFLNDPKILTPRLKKPMIRKQGVLEEVEWDEAINYTASRLNEIKEKYGPDSI
                     MGTGSARGPGNEANYIMQKFMRATIGTNNVDHCARVUHAPSVAGLAYSLGSGAMSNSI
                     PEIENADVLFIFGYNGADSHPIVANRIVKAKKNGAKLIVTDPRVTESARIADIHLPIK
                     GGTNMVLVNAFGNVLIEEGLYNKEFVQNHTQGFDEYKEIVKPYTAKYAEKITGIPEEL
                     IRKAMREYAKGKKAMILYGMGVCQFGQAVDVVKGLASIALLTGNFGRESVGIGPVRGQ
                     NNVQGACDMGALPNVYPGYQNVTDDKIREKFEKAWGVKLSPNNGYSLTQVPNLVLKEK
                     KLKAYYIFGEDPVQSDPDASEVREALDELEFVIVQDIFMNKTALHADVILPATSWGEH
                     EGVYTCADRGFQLMRKAIEPQGDVKPDWQIISEISTAMGYPMNYKNTKEIWDELRQLC
                     PSFLGATYEKIETQGCVQWPCKSESMEDKGTMYLYEGQKFSTPNGKGNLFAAEWRPPM
                     EVEDDEYPFSLCTVREVGHYSVRTMTGNCRTLSSLEDEPGRVQINSNDAEKLGIEDDE
                     LVRISSRRGSVITRATVTDRVKEGATYMTYQWWVGACNELTIANLDPISKTPEYKYCA
                     VKLEKLEDQELAEKCVREEYQSLKDKMTATNI"
     gene            4534..5367
                     /gene="fdhD"
                     /locus_tag="PC512_001557"
     CDS             4534..5367
                     /gene="fdhD"
                     /locus_tag="PC512_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase accessory
                     sulfurtransferase FdhD"
                     /protein_id="HDF2441303.1"
                     /translation="MNNIYSKTKLQENSKDKVFENSYSLVDYKYLNSFNVEVSKINEH
                     EVSIDNEEIIAEYPLSFILNDKYINTFLCTPYNLEELIVGFLKTKGYIENKKSLLKFE
                     INESERFAKVTIQEKQKNQDEQIIFLNSLDYITCAPVKSNIKINYDTIYSIMDRNLNS
                     SELFKNTGGVHSVSVFNFDKKIVTCEDVARHNAMDKAIGFCVLNDITLKDKIVAVSGR
                     ISLEMILKAAMTQIPIVVSKSAPTNLSIELSKKLNITLIGFVRGRRMNIYANPQRVIK
                     K"
     gene            5378..5551
                     /locus_tag="PC512_001558"
     CDS             5378..5551
                     /locus_tag="PC512_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441304.1"
                     /translation="MCTKKEEQRYSKCEICGVLIDDTDKVYNNTYNLCKKCKRNISTE
                     KIVKYINIYDESK"
     gene            5609..6160
                     /locus_tag="PC512_001559"
     CDS             5609..6160
                     /locus_tag="PC512_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HDF2441305.1"
                     /translation="MKNKIGSFVIADPNKCTGCRACEVACFTMHNQHNNVGYTVGTVD
                     IPVIPRLYLVKGDNFCMPIQCRQCEDAPCLNSCPQKAIVKENNIMSVNEEKCIGCKTC
                     LLACPFGAIDLLPQYEDGKEVEQVILDENKKIAYKCDLCKDNEKIACISACPQEALKL
                     VTPIDDKKAKNRQAALSLLLTNK"
     gene            6185..7561
                     /locus_tag="PC512_001560"
     CDS             6185..7561
                     /locus_tag="PC512_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase small subunit"
                     /protein_id="HDF2441306.1"
                     /translation="MIINIDKDLCTGCRECSKVCPVNAIEGEEGKPQEINLDRCVMCG
                     QCVQTCKSYASVIDEGFEFLQEKKQEREIPESINEPIFAAYNVCDIDKVKKALSDPNV
                     FTMVQCAPAVRVALGEDFGYYLGYLGAGKMAAALRALNFDRVYDTNFAADLTIMEEGS
                     ELIKRVTEGGTLPMFTSCCPAWVKFMEKNYPKLTNHLSSCKSPQQMGGAIFKTYGAEI
                     NNVDASKIFSVSIMPCTCKKYECDREEMDSSGYRDVDVVLTTRELAYLIKDMGIDFKN
                     LREEKFDSPLGSYSGAGTIFGVTGGVMEAAIRTGYELITGESIPDVEVKQVRGENGFR
                     KSTIKIGDLDLRVGVVSGLKNVIPVLEDLEKGKLDVDFIEVMTCPVGCVSGGGQPKIL
                     LEEYKELAYENRTKATYVHDEHLAIRKSHENPDIKKLYDEYLVEPLGEKSHHLLHTTY
                     CIGKEVAK"
     gene            7561..8076
                     /locus_tag="PC512_001561"
     CDS             7561..8076
                     /locus_tag="PC512_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HDF2441307.1"
                     /translation="MNYFVIADPDKCIGCRTCMIGCVVAHSDEDIFYQNLDEINFNPK
                     LSVIKTKEVSAPIQCRHCEDAPCAKACPNGGIVRVGNTIKINEENCIGCKTCMLACPI
                     GAIDIVTLKDVDEGKLCFRERMTANKCDFCIESPEGPACVNVCPTKAFTIVKDEDIDS
                     KVKNKRKLAIL"
     gene            complement(8154..9437)
                     /locus_tag="PC512_001562"
     CDS             complement(8154..9437)
                     /locus_tag="PC512_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugated bile salt MFS transporter"
                     /protein_id="HDF2441308.1"
                     /translation="MNTLLNNKFSIKNFSNAWVIVLGCMLIQAVPFSIVASIQPQFIS
                     YVVEGEGFSLASFSLIFTIGTIASAIASPFIGVLFSKVNIKILYLLGCIISSIAFATF
                     SICTELWQFYTVSCIVQIGATIISAIGIPVLISAWFDEESKGKALGFAFAGGSIGSIF
                     LQPLAVRLLATQGYSRSYLIFGIIALIVGIPVILFILRMPKDINEKVKSKGKKEKASD
                     TISPSVWGYTLKEAKKIKYFWIMTIGFIFVGIYVSSLSVQYPTYLRNYLNPILIGTVG
                     STFALFALIGNLFGGLLFDKFGQTKPLIISFVLVLIATLSLLLVDKSSTFAFVFAILK
                     GLSVFAYMIGPAYLTGSFFGQKEFGSIYGIVQLIFAVGFALGSTLFGLLVDNFGYRFS
                     WSIIILSVIIAYTLLIITSIGMKKLNKERLDKLMQ"
     gene            9625..10047
                     /locus_tag="PC512_001563"
     CDS             9625..10047
                     /locus_tag="PC512_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3783 domain-containing protein"
                     /protein_id="HDF2441309.1"
                     /translation="MSFEKINNNNLDKIHNRKCIMLVNFNKKELSLIKNVSNFAGIRD
                     HIILSDKNGENIIRDILDGNISNECENGIKSKSVIFNNTPSTQVNAFLEGLKKVRINR
                     PFTAMVTETSIDWTLNNLIENLVQERNAMSLGKTIEHK"
     gene            10149..11087
                     /locus_tag="PC512_001564"
     CDS             10149..11087
                     /locus_tag="PC512_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HDF2441310.1"
                     /translation="MKVLFTINYGKEKFDKIRELGYDVIHYSEDSIENNEDVNTADVL
                     VTYNPFERLDISKMKNLQYIQTTSVGIDQLPKEEVLKRNIKIANNRGGYSVPIGESIV
                     LYILEIYKNSAKFFKQQQNKEWKMDFSVSELYGQRVGFLGTGTISSEAAKRLKAFGVE
                     IWGVNTDGSSKKYFDKCFATEDMNIVFEECDIVVVAMPSTKSTDGIVNKDMFKLMKDG
                     SVFINVGRGNTVNQKDLEECVEKFRGVALDVFESEPLNKDNKLWECENVIVTPHNSWV
                     SDKNKERTFNMVYNNLKHYIMENKPVDNVVDISRGY"
     gene            11273..13297
                     /gene="ligA"
                     /locus_tag="PC512_001565"
     CDS             11273..13297
                     /gene="ligA"
                     /locus_tag="PC512_001565"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HDF2441311.1"
                     /translation="MSVKDEINKLIETINYHNERYYNQDSPEISDYEYDKLMKELISL
                     EEEHPELKRIDSPTNRVGGKPLDKFNQIVHKTPMLSLSNAFSEQDLRDFDKRVQEYVG
                     ENVEYVVEFKIDGLSVGLTYNNGEFEKGATRGDGVVGEDISQNLMTVKSIPLKINDKK
                     ELIVRGEVYISKDNFRKVNEQQEEQEQPLFANPRNLAAGSLRQLDPKLTAKRPLDIFV
                     FNMENIEEYDLESHSESLEYLEKLGFSVSQSYKVCKSIDEVIEHIEYWTDNRGNLDYE
                     IDGMVIKVNNIKQRDEMGYTAKSPRWAIAYKFPAEKKKTKIVDIIVEVGRTGTITPSA
                     ILEPVRLAGTTVSRATLHNEDYIREKDIKINDTVLVQKAGDIIPQVLEVIKEERTGDE
                     IDFKMPEKCPVCSEPTIRLEGEAAVKCINMSCPAQIRRGIIHFVSRDAMNIDGLGESI
                     ITLLLNEKIIQDVSDLYYIKKEDVVDLERMGEKSADNLINSIEKSKENDLWRLINGLG
                     IKFIGVKAAKILAYNFKDLDEVISATSEQLEELEEFGSIMANSVVEFFKEDKNMNVIN
                     KLKNVGVNTKSLDNTGEKVEKIFEGMKIVLTGTLPTLKRNDAKDMIEKRGGKATSSVS
                     KSTTFVLAGEEAGSKLTKANDLGIKVIDEERFLELLKLSSKDEVKAVLES"
     gene            13457..14806
                     /gene="rph"
                     /locus_tag="PC512_001566"
     CDS             13457..14806
                     /gene="rph"
                     /locus_tag="PC512_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HDF2441312.1"
                     /translation="MTRSYDRSNEQIRPVKITRDYTKYAEGSVLIEMGETKVICTASV
                     EEKVPPFLRNSGTGWINAEYSMLPRATQQRKIRDASRGKIDGRTQEIQRLIGRAIRSV
                     VDLNKLGERTIWVDCDVIQADGGTRTASITGAFVAVAEAIYKLYKAKIIKEMPITNFV
                     SAISVGIVNGIHMLDLCYEEDSKAQVDMNIIMTDKCEFVEVQGTGEEKPFSRADLNLL
                     LELGEKGNKELIRLQREALGEISDEILGMDYGNEVVIATNNAHKLEEIGEILKDFEYK
                     VYSLKDVDLAGIEIVEDGKTFEHNALIKARTIAKKTKLIAISDDSGLEVDALGKKPGV
                     YSARYAGEHATDEENRKKLLKAMQNIPMSKRNARFVSAIAVVFPDGKEFVVRGICEGM
                     IGFEEKGKNGFGYDSLFIVKGYDKTFGEIPSVIKNSISHRANALKLMKQEFIKRVVK"
     gene            14806..15276
                     /locus_tag="PC512_001567"
     CDS             14806..15276
                     /locus_tag="PC512_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDF2441313.1"
                     /translation="MKIGIVSDTHMMIKNMEKTIPYLKECDLIIHAGDNFTDSRYIHS
                     MTNVGIIAVKGNCDFDAVEEEVVFEVANKTIFLCHGDKYGVKYGTHMLEKKATEVDAD
                     IVIFGHTHTPFREIKDGVLYINPGSTSLPRGVSYKSFVIMDIEEDDIKIEEIRI"
     gene            15470..16756
                     /locus_tag="PC512_001568"
     CDS             15470..16756
                     /locus_tag="PC512_001568"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HDF2441314.1"
                     /translation="MKAELIKKEGNKVTLKITVDNNKFEAAVNKAYNKSRNKYNIPGF
                     RKGKAPRIVIETQYGKGIFYNDAIEILFPEVYPEAIKELDIDPIDNPDLDIEEISKDN
                     GLVMVLNVEVKPEFELGNYKGIEIAKVENTVSDENVDAKLQEMVEKNARLVSVEDKAL
                     EDGDTAIIDFEGFENGVAFDGGKGENYNLVIGSNTFIPGFEEQLVGKKAGEEVEVNVT
                     FPEEYHSQDLAGKPVVFNVKINDVKVKELSALDDEFAKDTSEFDSLDELKADVRAKLE
                     EEAKNRADAETRNSVVEKVAENTEIEIPEVMIQHQIDNMLNELNYQLQYQGFGLQQLL
                     EMTGRTMEELREERKEDAKKLVKSSLVLEAITKAEGIEATEEEFKAELEKMASAYNME
                     VEKIEASLRDADKEDIKGQIKIRKTIDLLVDNATIA"
     gene            16906..17490
                     /gene="clpP"
                     /locus_tag="PC512_001569"
     CDS             16906..17490
                     /gene="clpP"
                     /locus_tag="PC512_001569"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HDF2441315.1"
                     /translation="MALVPVVVEQTGRGERSYDIFSRLLKDRIIFLGDQVNDATAGLI
                     VAQLLFLEAEDPDKDIHLYINSPGGSITSGMAIYDTMQYIKPDVSTICIGMAASMGAF
                     LLAAGAKGKRLALPNSEIMIHQPLGGAQGQATDIEIHAKRILKIKETLNEILSERTGQ
                     PLEKIKMDTERDNFMSALEAKEYGLIDEVFTKRP"
     gene            17509..18759
                     /gene="clpX"
                     /locus_tag="PC512_001570"
     CDS             17509..18759
                     /gene="clpX"
                     /locus_tag="PC512_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HDF2441316.1"
                     /translation="MSKYEEKRQLKCSFCGKNQDQVRRLIAGPNVYICDECVELCDEI
                     IQEEIEDTIDEDTTSLPKPKEMMEILNDYVIGQEKAKKALSVAVYNHYKRIYSKKSSS
                     KDIEIQKSNILLLGPTGSGKTLLAQTLARTLNVPFAMADATSLTEAGYVGEDVENILL
                     KLIQAADFDIEKAERGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTVAN
                     VPPQGGRKHPHQEFLKIDTTNVLFILGGAFDGLEKIIQKRGGDKTLGFGAKIESKKEL
                     DLGKLYEKVLPEDLLKYGIIPEFIGRIPVLATLELLDEDALMQILQEPKNALVKQYKK
                     LLELDDVELEFEEGALRAIAKKAIERNTGARGLRSIVESVMMETMFEVPSRDNIKKVI
                     VTEKSVNEDSVNPIIVLKDQEESA"
     gene            complement(18830..19357)
                     /locus_tag="PC512_001571"
     CDS             complement(18830..19357)
                     /locus_tag="PC512_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HDF2441317.1"
                     /translation="MSEIILLFLIFLKIGAFSFGGGYAMLPFIQQEFISKYHFITNQE
                     FLDLLAISQSTPGPVAINSATFVGFKTAGFFGSLAATIGVTIFALIGLTIISKLFSKF
                     KNNKKVENLLTVLRPITLGFILSAAFSSAKEVNWDLYGIIAFIASFYLLYKGKIGSIA
                     IVFVFGILGILLTFL"
     gene            complement(19345..19857)
                     /locus_tag="PC512_001572"
     CDS             complement(19345..19857)
                     /locus_tag="PC512_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HDF2441318.1"
                     /translation="MLKLFLTFLKIGAFTFGGGYAMVPLIQDELVNKQKLLEQEEFID
                     YLSIAQSYPGVLAVNISVLLGYKLYGIPGVLICTLGSALPSFCIVLVLSYLYFKNSSS
                     KILDGFFKGVAPVVIALILYSFTSMFKKLPKSKTNILLLIIAVLSVGVFNISPIYLII
                     GGGVYSLCQK"
     gene            20037..22400
                     /gene="lon"
                     /locus_tag="PC512_001573"
     CDS             20037..22400
                     /gene="lon"
                     /locus_tag="PC512_001573"
                     /EC_number="3.4.21.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase La"
                     /protein_id="HDF2441319.1"
                     /translation="MEQNYTKIDHELPLIPLRGLAIFPYMILNFDIGREISLKALDQA
                     MMDEELIFLTSQKEAEVDEPGEEDFYHVGTICKVKQMIKLPGDTVRVLVEGVSRGRVK
                     KIEQEDGYFRAVIEEIVFDSDNLDSETEVEIEAFVRNVFDAFEEYINIGNRVSPEILI
                     SLADIEDVDRFIDTIAANIYLKSSQKQEILEEFDIRKRLELIYSILLEEIDILKIEKK
                     ITLRVKKQMNKVQKEYYLREQLKAIQKELGEEEDINSEADEYREKLKKIKAPKTTKEK
                     IEKEIDKFSKISSMSPDVSVSRNYLDTIFSLPWNKETKDKLDITKAKDILDEDHYGLE
                     KVKERILEYLAIRTLAKSLKGPIICLVGPPGTGKTSIVKSIARALNRKFVRISLGGVR
                     DEAEIRGHRRTYVGSIPGRIINGVKEAQTKNPVFLFDEIDKMAADYKGDPASAMLEVL
                     DPEQNKDFVDHYLEIPFDLSKILFVTTANSLSNIPRPLLDRMEVIEVSGYIEEEKLNI
                     AKKYLLPKQIKEHALKENFIKIDDETLRSIINHYTREAGVRTLERTIGKICRKVAKKY
                     VEDPTLEEVVINKSDLETYLGKDMFKYQLAEVNPQIGLVNGLAWTEVGGVTLEVEVNV
                     LKGKGEIVLTGKLGDVMKESAKTGISYIRSIVDKFDIDPEFYKTNDIHIHIPEGAVPK
                     DGPSAGITMALAVISALTKRPVPGNIAMTGEITLRGRVLAVGGVKEKLLAAHRAGITK
                     VLIPKECEADLDEIPENVKEKMEFVLVEHMDEVLEQALLKSGENNEN"
     gene            22390..23001
                     /locus_tag="PC512_001574"
     CDS             22390..23001
                     /locus_tag="PC512_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HDF2441320.1"
                     /translation="MKIRSSEITMSAVNKSQYPAEGIPEIALAGRSNVGKSSIINTLL
                     NRRNFARTSQTPGKTRTINFYLINNEFYFVDLPGYGYAKIAKSEKEKWGGIMERYLES
                     RQELCSIFLLVDIRHEPTADDKLMYEWIKHFGYNCVVIATKADKISRGQYQKHISIIR
                     KKLQMESSEKVIPVSSLKKTGVEELWEEIVNQYNQHGYEITVD"
     gene            complement(23267..24637)
                     /locus_tag="PC512_001575"
     CDS             complement(23267..24637)
                     /locus_tag="PC512_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2441321.1"
                     /translation="MKQKWIVLIIICIGVFMSTLDGSILNIANPTIAADFKINMSQIQ
                     WVVTAYMLVVTATMLFFGKLGDKVGSNRLYTLGFFIFTIGSFLCSMSNNLSTLISSRI
                     FQAVGASILMATGLGIVSNAFPANEKGKAIGITGAVVGIGNMSGPVIGGIILEHFGWP
                     SIFIINIPIGIIAVFLGIKFLPKPVLDEQNKSFDIPGLLLFASCTTLILLAMNEKGNT
                     RLYLGITALIIFLLLALREVKFEQSFIDLPLFKNRNFTVGNIIGVACYFPQMAVSFLL
                     PFYLEQLKNLSPMMAGYVMTVHPLIMVLIAPIAGSLSDKHGAKNILTASFSFMTISLV
                     GMALLKADSPLYLLIVCLVIFGLGLGAFSSPNNSSILADVPPQKQGYGGSFLATIRNL
                     SFALGTAFFSSFFAQSLTYNQKFKSHTSAYVIASNQSYWIAASVCFVGLILTVFFMRK
                     TDKSIS"
     regulatory      complement(24812..24927)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            25215..26294
                     /locus_tag="PC512_001576"
     CDS             25215..26294
                     /locus_tag="PC512_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2441322.1"
                     /translation="MEGKVKKAFPGGNTSQGSYSFFDYIIPENVKRVFCLKGGPGVGK
                     SSLMKKIYKEFLHRGYDIDLYHCPSDPSSLDGLVIKKLGVVLMDATAPHTMDPKLPGA
                     LDEIINLGDYWNTEELEKNKQEISVYDKDISNSFKRAFKFLKSAEPIFRDIEEKYSDC
                     MDYGKVNLVTEEFIKRLFDGVKSTGNLKREKHLFGSAITPVGCLDYTENILKDVKKVY
                     YLDGEIGTGKTTLLNKVYKKAIEKGLNVEVYHYPLIPEKIETVLLTDLDIGITISTTF
                     KEEDTIDLNQFLNREKLLKYEEDIKFDEKVLDDLICWAVLNLKRAKSKHDIIESYYSP
                     NMRFDEVGKLRDKLIKRILKYEENL"
     gene            26686..27366
                     /locus_tag="PC512_001577"
     CDS             26686..27366
                     /locus_tag="PC512_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HDF2441323.1"
                     /translation="MKKQYVFIILASTILGILVGTIFRDYSNEETVYTSKDKSIRKEI
                     KMTRKSIKELTKEKDKLDKEINSMKQNQKNSEEISEIETLRDSLSYSDVKGSGIILSI
                     DAIDEKTGNIANSIDYNKILVKVINELKVNGGKYIEINGQRINQYSEVVLAGSHININ
                     GVPVAQPYEIKCIGDKEKLSNYVDKGSKYLDSIQTNYPMKISIKTEENISMKKMNIPN
                     KLKYIKGD"
     gene            27359..28738
                     /locus_tag="PC512_001578"
     CDS             27359..28738
                     /locus_tag="PC512_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HDF2441324.1"
                     /translation="MIKIILEESSLPMLIPEKLAKKYNVFPVEFQDDNLVVEIEDEDI
                     YALQDLRLATGKEIILKKEKKELISEKIEKYYNSFELDEDYAKKLFENLLEKAIKENA
                     SDIHIEPFKEHLIVRMRVDGELKEVSKFLVDVYPSLSTVIKLKASMDITEKRLPQDGR
                     VDIKLGGNLIDIRVSSIPTVYGEKIVLRILNRDTFLKDKLELGFSEEAIKSINRIINK
                     RAGILLVTGPTGSGKTTTVYSLLNDLKGINKNIMTIENPVEYKMDGISQIQVNSKVGL
                     SFDVGLRAILRQDPDIIMVGEIRDAETAKIAVRAAITGHLVISTLHTNDAVSSIARLL
                     EMQIPPYLLNASLIGVISQKLVRKVCNHCSHEIMIKDNFSGDVNTKVAVGCEKCNDKG
                     YFGRTAIYEILEINDDIKTCIRNMEDSSTIKDVAQNNGMITFEDSCKRLINEKITTLE
                     ECLVVNEMI"
     gene            28909..29994
                     /locus_tag="PC512_001579"
     CDS             28909..29994
                     /locus_tag="PC512_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HDF2441325.1"
                     /translation="MRLSKNIFYNLEKFYLVLNRISDKEIRVICKEIGILLESGCEIT
                     KIFEIIESQSSKKAKNLLSIVSNHIQKGNSIAESFQITGIFSKFFISMIKAGETSGNL
                     DIIMSDLSNYYDKEYKLKMKIITISIYPIILIILSILSMLFIFVFVIPNFQVVFTNNG
                     IEPPLITRVLMGISTVVTNNLAYIIFSFILFSIGSIYFFITNDNIKKLINSLKFKIPF
                     IKKINQLVATTRFSRALSVLISSGIQIVEAIDMSASVIDNEFIYERLKISNNYIKKGN
                     SIGKSLNLANVFPKLFISMANTGEESGKLDKSLNVINKFYENELNNKIEQIMKFIEPM
                     LIVFMGLIIGTFILAMVVPMFDAITNF"
     gene            30048..30407
                     /locus_tag="PC512_001580"
     CDS             30048..30407
                     /locus_tag="PC512_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HDF2441326.1"
                     /translation="MINLINKKRKGFTLVEMIVVVTILGVISSIALVKYSKVQESAKL
                     NADYTNAANIVTAASMAINDDEKTIDSLSVETLKEKGYLNTVPVPQSTSGKFELVIND
                     SGTDISVNINSKQFYPK"
     gene            30460..31332
                     /locus_tag="PC512_001581"
     CDS             30460..31332
                     /locus_tag="PC512_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilus assembly protein PilM"
                     /protein_id="HDF2441327.1"
                     /translation="MAIIKKILNLEINDDYIRLVFLRKSHKKVFIDKSIIKEINFDIK
                     NDSNSIEKIKYIEDVVRFVKEEIGKSKILYKNLYFNIQIQDIVIRNVEVLNTKKKRDI
                     LSMIEFEITQYIPININNYSIKYKVINSKNDKLNIQVILFPKSIIQLIKNISENLNMN
                     PKTININFDILQKLINLNLIENFSEEGVFIECKKSQLIINITKDKKIRETYLLSKEGK
                     SYEFIKRLLRDFKYVYYYGIENCFIEEYFKYTDKSIEVNPLRLKDKVKVENNFDADLE
                     DNRINYISNIGMII"
     gene            31333..31776
                     /locus_tag="PC512_001582"
     CDS             31333..31776
                     /locus_tag="PC512_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441328.1"
                     /translation="MKVDKTINFLNGFKKTKPCNKIYKIIIVLILTCILFKSFMYVKS
                     INELEDYISQNKLVDKSRHTLPTTDKTREKFSKIKLNEIKKIYETIGINIITKISIDK
                     NKLEIEGVCSDLDVLNNLRKIKYIKYYYIDSIVRDGEYYRFRIKS"
     gene            31791..32375
                     /locus_tag="PC512_001583"
     CDS             31791..32375
                     /locus_tag="PC512_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441329.1"
                     /translation="MRLNNREKNLLKILLILVIILASDIAVSYLEENLTSLKNEKQNI
                     INKINNQDNYQIKDNKHIDDKYIESVESNKNEELKNNFNNSFLDKKTNKDIVLLVENE
                     LRDIVNVEYINQESSLDNHNKKQVNLEIKVNGELANLLKLEGVMKKLRLNNKLEKIEI
                     NKLKVNNFDVQNIPNEYKQEKDNIVECKMTVRVI"
     gene            32628..33665
                     /locus_tag="PC512_001584"
     CDS             32628..33665
                     /locus_tag="PC512_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC-C domain-containing protein"
                     /protein_id="HDF2441330.1"
                     /translation="MLGRNELCPCGSGKKYKKCCLNKDIVSERACRKTELSQKQYTDL
                     YSKLYDYSRQDKFKEECEKAKEMFYIMQNDSVNEKFERFFNTYLIQDHIMENKKVMTV
                     GFLEENGANLSQSEVSILKSMFESYVSIYEVKEVSAGKIVLKDCLSGNELCTEDVKLL
                     RSFKIGSCMIARIVDIEGTNILIDITISISNEVKDIILKDIMNLFNQYQDVYKDMKSF
                     LIYHTHILYKYIQQLLDPSIAEYLKRERDKNDTKVNSENELAEEECKVLDTLKENVEK
                     ENIDACIEFWNEYKKNHENIKGAENGWAAAVEYYVKKEAGQPITQVQISKKYDISSST
                     LGKRYKDLKIS"
     gene            33746..34111
                     /locus_tag="PC512_001585"
     CDS             33746..34111
                     /locus_tag="PC512_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441331.1"
                     /translation="MSLSLGNAIAVSTNFIKSNPAVPVYNGEEIYAVIYHIEIGYNNG
                     VSPDTKQYIIIDYKEFDLSMDKKNELINIAKEYCKSKGIVENENLEINLLDNEEAENF
                     LEKVFNNMKVIRGLITKKG"
     gene            34116..34433
                     /locus_tag="PC512_001586"
     CDS             34116..34433
                     /locus_tag="PC512_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441332.1"
                     /translation="MDYIGIENITPYENTYEFSVYEYDDEITLGSEKLYVCELRVVLI
                     KVNSLYVERLHKSVEAMVLVKNLKKDLDKTLVVNKIKNFVLDEIWVENLVKENIEVIF
                     VES"
     gene            34481..36085
                     /locus_tag="PC512_001587"
     CDS             34481..36085
                     /locus_tag="PC512_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441333.1"
                     /translation="MLRVSNVKLGIDKDISLLKDVILKKLKIKEKNLVKYSIYKESID
                     ARKKGKMEFVYSVDVEVKDENKILNSKIKDVTKIKEIRYVNVPVGDKKLKNNPLVIGS
                     GPAGLFAGLLLAQMGYEPIILERGLDVDSRTKDISDFWTTRKLKNNSNVQFGEGGAGT
                     FSDGKLTTRIKDIRCRKVLEELVQFGAPDEILYSHKPHVGTDILKNVVKNIRNEIISL
                     GGQVRFNSKVTDIVVSNDSIQSVIINDTEKIDTDTIILAVGHSARDTYEMLYSRGIKI
                     VQKPFAIGARVEHPQDLINKAQYKDFYNHPRLGAADYRLIEHVSNGRTAYTFCMCPGG
                     SVIASASNDFEIVTNGMSEHARDKINANSAFLVNVTPEDFKSDNPLAGVHFQQKYEKL
                     AFELGGKNYNAPVQLVGDFINNKTSLNLGSVEPSYRPGYTLTNLSECLPSFVTETMRE
                     AFISLDKKLNGFAMYDAVLTGVETRSSSPIRIVRDENTLESVSIKNLYPCGEGAGYAG
                     GIVTAAVDGIKCAEKIIQKYTNNTKI"
     gene            36209..37837
                     /locus_tag="PC512_001588"
     CDS             36209..37837
                     /locus_tag="PC512_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HDF2441334.1"
                     /translation="MNIIISLMGGLGLFLYGMNLMGEGLQKSAGTKLKKIIKLLTSNL
                     FMGVLVGTGVTAVIQSSSATTVMVVGFVNAGIMTLKQAIGVIMGANIGTTVTAQLVSF
                     DLTGMAPVALGVGIILYLFGNKPRIKNIAEILIGFGILFTGMDFMKMAVEPLRDYQGF
                     TDLLVTFGRYPLLGLLLGFGITAIIQSSSASMGMLVALAAEGLVPLSAALPILYGQNI
                     GTCVTSLLSSIGANKNARRAAMMHLIFNVLGTVIFLIFLNKPVVSMVTSWDPSNVARQ
                     IANTHTLFNIISVLILLPFTSLIIKLAIKLVPDRAGDIDEDETKTIKYIDDRMIETPS
                     IALANTIKEALRMGEKAKESLNASMEALVEHSTEKIDKTYRRERLINDLQKAILNYLL
                     KLSKAALDDDSREVVDTLFNTVNDIERIGDHAKNIAELSQVAIDSNIYFSEEGQSELD
                     VMYNRVVSAYTYALESMRSDNVDLACKVIKIEEQVDIMEKSCRANHMYRLNNNLCSIE
                     NGVIYLDVISNLERISDHAVNIAQQVIAKRLGND"
     gene            38102..39451
                     /locus_tag="PC512_001589"
     CDS             38102..39451
                     /locus_tag="PC512_001589"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HDF2441335.1"
                     /translation="MGKINFDYSKATEFFCQNEIDVMQPYVDVAHDMLHNKTGLGNTF
                     LGWIDLPKNYDKEEFDRIKKSADKIKSDSDVLLVIGIGGSYLGSRAAIDMVSHSFRNG
                     LKKEQRKAPEVYFVGHNISSTYIMDLLDIIEGKDISVNVISKSGTTTEPALAFRIFKD
                     YLEKKYGKEEARKRIYATTDASKGALRQLATEEGYETFVIPDDVGGRFSVLTAVGLLP
                     IAAAGLDIDAMMKGANDAREAFQNPDLKSNDSYRYAVARTILHRKGKDVELLVNYEPQ
                     LHYVSEWWKQLYGESEGKENKGLFPASVDFSTDLHSMGQYIQDGKRLLFETVLNVENC
                     KRNITISSEEVDLDGLNYLAGKTVDFVNHKAFEGTLLAHTDGKVPNLVINIPQLDEYN
                     FGYLVYFFEKACGISGYLLGVNPFDQPGVEAYKKNMFALLGKPGYEKEKEELEKRLK"
     gene            39607..40686
                     /locus_tag="PC512_001590"
     CDS             39607..40686
                     /locus_tag="PC512_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HDF2441336.1"
                     /translation="MSRRKKGISLVILVAIISSILSSFLTIILVKDNLVSKSTGSSTP
                     IVVNDDGKSQNIYQAVAEKATPSVVGITTTSVDTSNMFAIPTETQGVGTGIIVDSNGY
                     ILTNSHVISDGQATSVNVLFNDGSTTSGKVVWFDQQLDLAIVKVDKTGLTPAEFADSD
                     KVKVGDISIAIGNPLGLDFQKTVTQGIISGLDRTIQTEKTNMTGLLQTDASINAGNSG
                     GPLLNQKGQVIGINTAKASQAEGLGFAIPINTAKSIVEEVIKNGKYEKVTLGIKGTDV
                     SNYEAATGTKLSTDKGVYVAEVISGSSAEKAGVKVGDIITKVGDTDITGMNDLNKKLY
                     TFSKGASTKITVNRGGKAVTINVNF"
     gene            41031..41939
                     /locus_tag="PC512_001591"
     CDS             41031..41939
                     /locus_tag="PC512_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HDF2441337.1"
                     /translation="MNPLVINLQKCSIHDGPGIRSTVFFKGCPLECVWCHNPESQTYT
                     KQVLYNEERCSKCEACINICPHKAIYKGETKICLDQDKCEFCETCLDYCVNNAREIVG
                     QEYSVRDLVKEIEKDRIFYEESGGGVTLSGGEVMAQDMDFICGVINMCKSKGIHVAID
                     TCGYAKSENYERVAKCADLFLYDIKLIDEDKHIKFTGKSNDLILKNVKILSELGANIN
                     IRIPLIVGVNVDDENLEVKKMIEFLKPLNIQAVSLLPYHNIGKHKYDKIYKKYEGEEL
                     QRPSEEKLEEIKRLFEASNFNTKIGG"
     gene            41944..44313
                     /locus_tag="PC512_001592"
     CDS             41944..44313
                     /locus_tag="PC512_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HDF2441338.1"
                     /translation="MARGTFERTKKLREESINAEPHISIERAVLMTEAYKKYEGSVEI
                     PVLRALSFKHYIENRTLSINDGELIVGEKGDSPNGAPTYPEICCHTMEDLEVMHNRDI
                     INFSVSEEARKIHKEEIIPFWKKRQTRDKIINAMTPEWLAAYEAGMFTEFMEQRAPGH
                     TVCGDTIYKKGFLDLKKDIEARLKELDFLNDLDAYNKKADLEAMAIACDAMVILGKRY
                     AEKARQMAEEETDEAKKQDLLLIAETCDVVPAHKPETYHQAIQMYWFVHIGVTTELNI
                     WDAFTPGRLDQHLNPFYERDVENGILDRDRAQELLECLWVKFNNQPAPPKVGITLKES
                     STYTDFANINTGGINPDGQDGVNEVSYIILDVMDEMKLIQPSSNVQISKKTPQKFLKR
                     ACEISRKGWGQPAFYNTEAIVQELMEAGKTIEDARLGGTSGCVETGCFGKEAYVLTGY
                     MNIPKILELTLNNGYDPISKKQIGIETGDPRNFQSYEELFEAFKKQLHYMIDIKIEGN
                     AVIENICAKHMPCPLMSTIVDDCIEKGKDYQRGGARYNTRYIQGVGIGTITDSLTAIK
                     YNVFDKKKFDMDTLLKALDANFEGYEAILNLVSNKTPKYGNDDDYADEIMQEIFNAYY
                     NEVTGRPTVCGGEYRVDMLPTTCHIYFGEIMGASPNGRLCAKPVSEGISPEKGGDTNG
                     PTAVIKSCAKMDHIKTGGTLLNQRFAPSVVQGEKGLDNMANLVRAYFNMDGHHIQFNV
                     FDKNVLLEAQKNPQDYKDLIVRVAGYSDHFNNLSRTLQDEIIGRTEQTF"
     gene            44638..45441
                     /gene="proC"
                     /locus_tag="PC512_001593"
     CDS             44638..45441
                     /gene="proC"
                     /locus_tag="PC512_001593"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HDF2441339.1"
                     /translation="MKTLGFIGSGNMGSAMIGGIVQSGLVKAEDITVSDLSQVALDKV
                     KEEFGVNTTTDSKVAVTNSDVVIVALKPNICEKALTPLKELIDANKIIVSIAAGKTIE
                     SLESFIGSDKKIVRVMPNTPALVGEGMSALCKNSNVTDEELNMIKALFESFGEAEIVS
                     EYLMDTVTGISGSSPAYVFMFIEAMADAAVLAGMPRQQAYKFASQAVMGSAKMVLETG
                     KHPGELKDMVCSPAGTTIEAVKVLEEEGFRAAVIKSIVACIDKSKDMSK"
BASE COUNT        18698 a         4824 c         8259 g        13793 t
ORIGIN      
        1 tttgaaatat aaagtttttg tatctaaaat attttatttg taaaatagta attaattatt
       61 gtaagctata atatgagagt attatggtta atgtgaattt taaagatatt attaaatata
      121 taaattagaa tactattaaa cggataaatg gaggagttat tatgtctaag atattagtag
      181 tagatgatga gttagatatg ttaaagttga ttgaaaatgt gttgaaaaga gatggacatg
      241 aagtaaaggt aattagtgat gtagaaaaag ctatgaacat ggattttaat tattttaatc
      301 taataatatt agatgttatg atgcctaaga tggatggttt tgaagtatgt aaaactataa
      361 gaaataaggt tgattgtcca atactgtttt tgacagcaaa aaatatggaa agtgatatta
      421 tgtacggtct tggtataggt gcagatgact atataaccaa accttttggt gtaggagaat
      481 taagggctag gataactgct catttaaggc gagaaagtag agaaaaaaag aatttattaa
      541 ctatctcaaa tgttcaattt aactttttag gcaaagaagt ttcaattgat ggtaaaaaaa
      601 ttaattttac taaaagtgaa tatctaatat gtgaatttct agcaaaaaat aagggacaag
      661 tattttcaaa agaaagaata tatgagtcgg tatatggttt tgatggagaa agtgatataa
      721 gtactatcac agagcatata aaaaatatac gaagcaaatt aaaacaatat gatatttata
      781 caatagaaac tgtatggggg atagggtata aatgggtgta ataagtataa gtgttgttta
      841 gtgaaaatat tatatatatc tacaaaatgt ttgtaaaata ttaatctata tattaaaatt
      901 taatttatag attaatattt tttgtaaatg acaaaattgt aaggtatttt gttataaaat
      961 attaagattc atagtgtata ctaataatat agtatttagt ataaatcttg agcaaaggat
     1021 ggttatttct aatggataga ctaaagaata ttagaaagag tttactacag tatacatttt
     1081 tatttttgtt aataggtata acaatttacc tagtgtttaa aacattggat attaaaatgc
     1141 tatcaaatgt tatggttatg gtagataaga agtttttatt cataggtgct ttggcaataa
     1201 tgtgtcacat aatgcttgaa ggagtagtaa tgaagataat tatagaaagc actcacaaag
     1261 ttaatattag atttattggt tttaagctag ccattatggg attttattat aatttaataa
     1321 ctccttttgc ttcaggaagc caaccagtac agatatatgt acttaaaaaa tgtaaaatgc
     1381 cacttagtaa ggcaagtgca gttgttacca ataagtctat tatcttccaa atagtagtta
     1441 ctttttattg tacaatactt gttttaatga attttgctat gttagaaaaa caaatgaaaa
     1501 tgattatgcc tctagtgttt ctagggatag ccattaattc atttgtctta attatgataa
     1561 tattagttat tttaaatcct aaaaaaataa aatattttat gagaattact ataaagcatt
     1621 tatcaaaaat taagttttta aaatttttag ataataagat tgaatccata gaaagtttta
     1681 tagatgatta tagtaaagca ataaattttt ttgcaaagaa taaaaaggta ttaatttcaa
     1741 ctataatagt aacttttatt caattaagtg cttactttag tgtttcattt tggatatata
     1801 aagcatttaa tttacaaggt tatagctata tttatatact gacattacaa gcatttttat
     1861 atatggcaat atctccaata ccaacacctg ggaatgtagg agctaatgaa ttagcctttt
     1921 tcactatatt caaatcagta ttccctcaac ctttgatggg atatgcagta tttttatatg
     1981 gtggatttat gtactatttg attctgattg gaagtggaat atttactgta attactcact
     2041 atagaatgaa aaatagaatt ggcagaaata ttgttttaag tgaaaactaa ataagtttaa
     2101 agaatatata ttgagtatat taaaaaatat gtcataagaa ctagaatatt ttaattaaat
     2161 ggttgaaata taaagattat tatgacatat tttttttgaa atttaagagg aattgtgaga
     2221 aaattgttga atttaataga tagtattgca aaatatttat gattttgcat attataaaaa
     2281 cactcattat ctttaagata aattttactt atcaggggat aaatctaagg ggggaattgt
     2341 atggagaaaa aaattttaac agtttgtcca tactgtggag ctggatgcca attatatcta
     2401 gtagtaaaag ataataagat attaagagct gaaccggcta atggtagaac aaatcaagaa
     2461 agtttgtgtt taaaaggtcg ttatggatgg gattttctaa atgaccctaa aattctaaca
     2521 cctaggctaa aaaagccaat gataagaaaa caaggtgtac tagaagaggt tgaatgggat
     2581 gaggctataa actatacagc ttcaagacta aatgaaatta aagaaaaata tggtcctgat
     2641 tctattatgg gaacaggttc tgcaagagga cctggtaatg aagcaaacta tataatgcaa
     2701 aaatttatga gagctacaat aggaactaat aatgttgacc attgtgctcg tgtctgacat
     2761 gcaccatctg tagccggtct ggcttactca ttaggtagtg gtgcaatgtc taattctata
     2821 ccagagatag aaaatgcaga tgttttattt atatttggat ataatggagc agattcacat
     2881 ccaatagtgg caaatagaat agtaaaagct aaaaaaaatg gtgctaaatt aattgttact
     2941 gaccctagag taactgaatc tgcaagaatt gctgatatac atctacctat aaaaggtgga
     3001 acaaacatgg ttttagtaaa tgcttttgga aatgtattaa tagaagaagg tctttacaat
     3061 aaagaatttg ttcaaaatca tacacaagga tttgatgagt ataaagaaat tgttaaacca
     3121 tatacagcta aatatgctga aaagattaca ggaatcccag aagagcttat aagaaaagct
     3181 atgagagaat atgcaaaagg taaaaaagct atgatacttt atggaatggg tgtctgtcaa
     3241 tttggtcaag ctgttgatgt agttaaggga cttgcatcaa ttgctctact tacaggtaat
     3301 tttggtagag aaagcgttgg aataggacct gtacgtggac aaaataatgt tcaaggagct
     3361 tgtgatatgg gagctcttcc taatgtatat cctggctatc aaaatgtaac tgatgataag
     3421 ataagagaaa agtttgaaaa agcttggggg gtaaaattat ctcctaataa tggttatagt
     3481 ttaactcaag ttccaaattt agtactaaaa gagaaaaagc ttaaagctta ttatatattt
     3541 ggagaagacc cagtgcaaag tgacccagat gcatcagaag ttagagaagc attagatgaa
     3601 ttggaatttg tcattgttca agatatattt atgaataaga cagcacttca cgctgatgtt
     3661 atacttccag ctacttcttg gggagaacat gagggagtat atacatgtgc agatagagga
     3721 ttccaattga tgagaaaagc tatagagcca caaggagatg taaaaccaga ctggcaaatt
     3781 ataagcgaaa tttctacagc aatgggatat cctatgaatt ataaaaatac taaggaaata
     3841 tgggacgaac ttagacaatt atgtccaagt ttcttaggtg ctacttatga aaagatagaa
     3901 actcaaggat gcgttcaatg gccttgtaag agtgaaagta tggaagataa aggaactatg
     3961 tatctgtatg aaggtcaaaa gttttctact cctaatggta aaggtaattt gttcgctgct
     4021 gaatggagac cccctatgga agttgaagat gatgaatacc catttagttt atgtactgta
     4081 agagaagttg gacactattc agtaagaaca atgactggta attgtagaac acttagttca
     4141 ttagaagatg aaccaggacg tgttcaaata aattctaatg atgctgaaaa attaggaatt
     4201 gaagatgatg aattagttag aattagttca agaagaggaa gtgtaataac aagagcaaca
     4261 gttactgata gagttaagga aggtgcaaca tatatgactt atcagtggtg ggttggagct
     4321 tgcaatgaac ttacaatagc aaatttagat cctatatcta aaacaccaga gtataaatat
     4381 tgtgctgtta aacttgaaaa acttgaagac caagaattag cagaaaaatg tgtaagagaa
     4441 gagtatcaaa gtttgaaaga caaaatgaca gctacaaata tctaatgatt tattagattt
     4501 aagatttata aaaggcagaa aggctaatat tttatgaaca atatatactc aaaaactaaa
     4561 ttacaagaaa atagtaagga taaagttttt gaaaatagtt atagtctagt ggactacaaa
     4621 tatttaaatt cttttaatgt agaagtaagc aaaataaatg aacatgaagt atcaatagat
     4681 aatgaagaaa taattgcaga atatccactt agttttattt taaatgataa atatataaat
     4741 acatttttat gtaccccata taatttagag gaacttatag taggattctt gaaaacaaaa
     4801 ggatacatag aaaacaaaaa aagcttatta aaatttgaga taaatgagag tgaacgtttt
     4861 gcaaaagtaa ctattcaaga gaaacaaaaa aatcaagatg agcaaattat atttttaaat
     4921 tcactagact atataacatg tgctcctgta aagagcaata taaaaataaa ttatgatacg
     4981 atttacagta taatggatag aaatttaaat tcatcagaat tatttaaaaa tactggtggg
     5041 gtacatagcg tatctgtatt taattttgat aaaaaaatag tcacttgtga agatgtagca
     5101 aggcataatg caatggataa ggctattgga ttttgtgttt taaatgacat aacattaaaa
     5161 gataaaattg tggctgtaag tggaagaata tcattggaaa tgatattaaa agcagctatg
     5221 actcaaattc ctattgtagt atcaaaatca gcaccgacta atttatcaat agagctttct
     5281 aaaaaattaa atataacgct tattggattt gtaagaggaa gacggatgaa tatttatgca
     5341 aatccacaga gagttatcaa aaagtgagaa tgaatatatg tgtactaaaa aagaagagca
     5401 aagatattca aagtgtgaaa tctgtggagt attaattgat gatactgata aggtgtataa
     5461 taacacatac aatttgtgca aaaaatgtaa acgaaatata agtactgaga aaatagtgaa
     5521 atatataaat atatatgatg aaagtaagta gacatatgat gaaaataact agagggttgg
     5581 aaatatacaa attgaaaggt gggataatat gaaaaataaa ataggctctt ttgtaatagc
     5641 agacccaaac aaatgtacag gttgtagagc ttgtgaagta gcttgtttta caatgcataa
     5701 tcagcataat aatgtgggtt atacagttgg aacagttgat atacctgtta tacctagact
     5761 ttacttagta aaaggtgaca atttctgtat gccaatacag tgtagacagt gtgaagatgc
     5821 tccttgttta aactcatgtc cacaaaaagc tatagttaaa gaaaacaata ttatgtctgt
     5881 aaatgaagaa aagtgtatag gatgtaaaac ttgtctgcta gcatgtcctt ttggagctat
     5941 agacttactt ccacaatatg aagatggtaa agaagtagaa caagtaattt tagatgaaaa
     6001 taagaagata gcttataaat gtgacttatg taaagacaat gaaaaaatag cttgtataag
     6061 tgcatgtcct caggaagcat taaaacttgt tactccaata gatgacaaaa aagctaagaa
     6121 tagacaagct gcacttagtt tattgttaac aaataaataa aggatacagg ggtaggtgac
     6181 gtttatgata ataaatatag ataaggattt atgtactgga tgtagagaat gttcaaaggt
     6241 ctgtccagta aatgctattg aaggtgaaga gggaaagcca caagagataa atttagatag
     6301 atgtgttatg tgcggtcaat gtgttcaaac ttgtaaatct tatgcttcag ttatagatga
     6361 aggatttgag tttttacaag agaaaaaaca agaaagagag ataccagagt ctataaatga
     6421 acctatattt gcagcataca atgtatgtga tatagataag gtgaagaaag ctttaagtga
     6481 cccaaatgta ttcactatgg tccaatgtgc accagcagtt agagttgctt taggagaaga
     6541 tttcggatat tatttaggat acttaggtgc tgggaaaatg gcagcagcac ttagagcttt
     6601 aaattttgat agagtctacg atactaattt tgcagcagat ttaactataa tggaagaagg
     6661 tagtgaatta attaaaagag tgacagaagg tggaactctt ccaatgttta catcttgttg
     6721 tccagcttgg gtaaaattca tggaaaaaaa ttatcctaaa ttaactaatc atttatcttc
     6781 ttgtaaatca cctcagcaga tgggtggtgc aatatttaaa acttatggtg cagagataaa
     6841 taatgtagat gcatcaaaga tatttagtgt ttctataatg ccatgtacat gtaaaaaata
     6901 tgaatgtgat agagaagaaa tggattctag tggatataga gatgtagatg tagtattaac
     6961 tactagagaa ctagcttatt taataaaaga catgggaatt gattttaaaa atttaagaga
     7021 agaaaaattt gatagtcctt taggtagtta tagtggagct ggaactatct ttggtgttac
     7081 tggtggggtt atggaagctg ctataagaac aggatatgag cttataactg gagaaagtat
     7141 tcctgatgta gaagtaaaac aagtaagagg agaaaatggt tttagaaagt caactattaa
     7201 aataggagac ttagacttaa gagttggagt agtaagtgga ttaaaaaatg taataccagt
     7261 gcttgaagac ttggaaaaag gaaaattaga tgtagatttt attgaagtta tgacttgtcc
     7321 tgttgggtgt gtaagtggtg gaggtcaacc aaaaatttta ctagaagaat ataaggaatt
     7381 ggcttatgaa aatagaacaa aagcaacata cgtgcatgat gaacatttag caattagaaa
     7441 atctcatgag aatcctgata ttaaaaaact gtatgatgaa tatctggtag aaccattagg
     7501 agaaaaatct catcatctat tacacactac atattgtata ggaaaggaag tggctaagtg
     7561 atgaactatt ttgttatagc agaccctgat aaatgcatag gatgtagaac ttgtatgata
     7621 ggatgtgtag ttgcacattc agatgaagat attttttacc aaaatctaga tgaaataaat
     7681 tttaatccaa aactttctgt cataaagaca aaagaagtaa gtgctccaat acagtgtaga
     7741 cattgtgaag atgctccttg tgcaaaggca tgtccaaatg gtggtatagt tagggttggg
     7801 aacacaataa aaataaatga agaaaattgt ataggatgta agacttgtat gttagcatgt
     7861 cctataggtg caatagacat agttacatta aaagatgtag atgaaggaaa gctttgcttt
     7921 agagaaagaa tgacagcaaa taagtgtgat ttttgtatag aatcgccaga agggcctgca
     7981 tgtgtaaatg tttgtccaac taaggcattt actatagtta aggatgagga tatagatagt
     8041 aaagttaaaa ataagagaaa attagctata ttgtaatata aaaaagatgg agttttattt
     8101 atgattaaaa gctccatctt ttttattata atatttatat atctaaaaat caattattgc
     8161 attagtttat ctaatctttc tttattcaat tttttcattc ctatagaagt tataataagt
     8221 aaagtatagg caattataac tgataaaatt ataatagacc aagaaaatct gtatccaaaa
     8281 ttatcaacta acaatccaaa taatgttgaa cctaatgcaa atcccactgc aaaaattaat
     8341 tgtacgattc catatatgct accaaactcc ttttgaccaa agaaagagcc agttaaataa
     8401 gcaggaccaa tcatataagc aaatacagaa agacctttca aaatggcaaa tacaaatgca
     8461 aaagtagaag atttatctac caatagtaat gataaagttg ctataagaac caatacaaaa
     8521 gatataataa gtggctttgt ttgaccgaat ttatcaaaca ataatcctcc aaataaatta
     8581 ccaatgagag caaataaagc aaatgtggag cctactgttc ctattagaat aggatttaga
     8641 taatttctaa gataagttgg atattgtacg gataatgatg aaacatatat accaacaaat
     8701 ataaatccaa tagtcataat ccaaaaatat ttaatttttt tagcttcttt taatgtataa
     8761 ccccatactg aaggagaaat tgtatcagat gctttctctt ttttaccttt agattttacc
     8821 ttttcattaa tatctttagg catcctgagt atgaataata ttacaggtat accaactatt
     8881 aatgctataa ttccaaatat tagataagaa cgactgtatc cttgagttgc taataagcga
     8941 actgcaagtg gttgtagaaa tatactacca atagaaccac cagcaaaagc aaagcccaaa
     9001 gcttttcctt tgctttcttc atcaaaccaa gcacttatta aaacaggtat tcctatagca
     9061 gatataattg tagcgccaat ttgaacaata catgatacag tgtaaaattg ccatagttca
     9121 gtacatatag aaaaagtagc aaaagcaata ctagaaatta tacaacctaa taaatatagt
     9181 atcttaatat tgactttaga aaataataca cctataaaag gtgatgcaat tgctgaggca
     9241 atagtaccaa tagtgaatat tagagaaaaa gaagctaaac taaagccttc tccttctaca
     9301 acataactta taaattgagg ctgtatactt gctacaatac taaatggaac agcttgtatc
     9361 aacatacaac caagtactat aacccaagca tttgaaaagt ttttaatgct aaatttattg
     9421 tttagtaatg tattcatggt atctctcctt taggttatga tttgtagata ttaatctaat
     9481 tattctaatt ttatatatta gttttggata gcccaactat ttaaatataa tttgggtatt
     9541 aatataaaaa ttaactataa aaattgatta ttttaaatgt atggggtaaa ttaaagtata
     9601 taaataaatg aaaggatgga taaaatgtca tttgaaaaaa taaataataa taacctagat
     9661 aaaatacaca acaggaagtg tattatgctt gtaaacttta ataaaaaaga attatcatta
     9721 attaaaaacg taagtaactt tgctggaata agagaccata tcatcttaag tgataaaaat
     9781 ggagagaata taataagaga cattttagat ggaaatatat caaatgaatg tgaaaatggg
     9841 attaagagta agtctgtaat atttaataac actccaagca cacaagtaaa tgcattttta
     9901 gaagggctaa aaaaagtgag aataaataga ccttttacag ctatggtaac agagacatct
     9961 attgattgga cattgaataa tttaatagaa aatttagttc aagaacgtaa tgctatgtct
    10021 ttaggaaaaa caattgaaca taagtaaatt taagatatct tatagtaatt ttaactaatg
    10081 tacattgagt atcatattat attttagaat ataaaatttt aaatgtgggt agatggagga
    10141 gatttgagat gaaagtttta tttacaataa attatggaaa agaaaaattt gataaaataa
    10201 gagaattagg ctatgatgtc atacattact ctgaagatag tattgaaaat aatgaggatg
    10261 taaatacagc agatgtacta gttacataca atccatttga gagattagat atttctaaga
    10321 tgaaaaattt acaatatata cagacaacta gtgtaggtat agaccaactt ccaaaagaag
    10381 aggtattgaa gagaaatatt aagatagcta ataatagagg cggatatagt gtacctattg
    10441 gtgaaagtat tgtattgtat attttagaaa tatataaaaa tagtgcaaaa ttttttaaac
    10501 aacaacaaaa taaagaatgg aagatggatt tttctgtatc agaattgtat ggacaaagag
    10561 ttggattttt aggaacaggt actatatctt cagaagcagc aaaaagatta aaagcttttg
    10621 gtgtagaaat atggggtgtc aatactgatg gaagtagtaa aaaatacttt gataagtgtt
    10681 ttgctactga agatatgaat attgtatttg aagaatgtga tatagtagtt gtagcaatgc
    10741 cttctacaaa aagtacagat ggaatagtaa acaaagatat gtttaaactt atgaaagatg
    10801 gttctgtatt tataaatgta ggtagaggaa atacagttaa tcagaaagat ttagaagaat
    10861 gtgtagagaa atttagaggg gtagcattag acgtatttga aagtgaacct ttaaacaagg
    10921 acaataagtt gtgggagtgc gaaaatgtca tagtaactcc tcataattct tgggtgtcag
    10981 ataaaaacaa agagagaaca tttaatatgg tttataataa tttgaaacac tatataatgg
    11041 agaataaacc tgtagataat gttgtagaca tatcaagagg ctattaaaaa taaaaaattt
    11101 tgataaaaat aaaaactctt attagtcgta ttaaagatac taataagagt tttttttgta
    11161 ataaatttaa agcccaaaaa gtgatatact aaaaaatata taaataggag ataattaatt
    11221 atagggaaat ttcaaaataa tttaatttta aaaatatgaa gaggtgcaaa aagtgagcgt
    11281 aaaagatgaa attaataaac ttatagagac aataaactac cataatgaaa ggtattataa
    11341 tcaagatagc ccagaaatat cagattatga atacgataag ttaatgaagg agttaatttc
    11401 tttagaagaa gaacatccag aactaaagag aattgattct ccaacaaata gggtaggagg
    11461 taagccatta gataagttca atcaaattgt acataaaact cctatgttga gtttatcaaa
    11521 tgctttttca gagcaagatt tgagagattt tgataagaga gttcaagaat atgtgggaga
    11581 aaatgttgaa tatgttgttg aatttaaaat agatggtctt tctgtaggtc taacttataa
    11641 caatggagag tttgaaaaag gagcaactag aggagatgga gttgtaggag aagatatttc
    11701 tcaaaactta atgacagtaa aaagcatacc tcttaagata aatgataaaa aagaactaat
    11761 agttagagga gaagtatata tatcaaaaga taattttaga aaagtaaatg aacaacaaga
    11821 agaacaagaa cagccattat ttgctaatcc aaggaatctt gcagctggtt cattgagaca
    11881 attagaccca aaactaacag caaagagacc attagatata tttgtattta atatggaaaa
    11941 tatagaagaa tacgatttag aaagtcacag tgaatcacta gagtacttag aaaaactagg
    12001 attttcagta agtcagagtt ataaagtttg taaaagtata gatgaagtta ttgagcatat
    12061 tgaatactgg acagataaca ggggtaattt agactacgaa atagatggta tggtaataaa
    12121 agtaaacaat ataaaacaaa gagacgaaat gggatataca gccaaaagtc ctagatgggc
    12181 aattgcatat aaattcccag cagaaaagaa gaaaactaaa atagtagata taatagtaga
    12241 agttgggaga actggtacaa taacaccttc agcaattctt gaaccagtca gacttgcagg
    12301 tactactgta agtagagcta cacttcacaa tgaagattat ataagagaaa aagatataaa
    12361 aataaatgat acagtattag ttcaaaaagc aggggacata atacctcaag ttttagaagt
    12421 tataaaagaa gaacgtactg gagatgaaat agattttaaa atgccagaaa agtgtccagt
    12481 ttgttcagag ccaacaataa gattagaagg agaagctgct gtaaaatgta tcaatatgtc
    12541 ttgcccagcc caaataagaa ggggaattat acactttgtg tcaagggatg caatgaatat
    12601 agatggattg ggagaatcta taattacact gctattaaat gaaaaaatta ttcaagatgt
    12661 atctgattta tattatataa aaaaggaaga tgtagtcgac ctagagagaa tgggcgaaaa
    12721 atctgctgac aatttaataa attcaattga aaaatcaaaa gaaaatgatt tatggagact
    12781 tataaatgga ttaggtatta aatttatagg agttaaagca gctaagatac ttgcatataa
    12841 ctttaaggat ttagatgaag taatttctgc aactagtgag caactagaag aattagagga
    12901 atttggaagt ataatggcaa acagcgttgt cgagtttttt aaggaagaca aaaatatgaa
    12961 cgttataaac aagttaaaaa atgtaggagt aaatacaaaa tcattggata atacaggtga
    13021 aaaagtagaa aaaatatttg aagggatgaa aatcgtattg actggtacac ttcctacatt
    13081 aaaaagaaat gatgcaaaag atatgataga aaaaagaggt ggaaaagcta catctagtgt
    13141 tagtaaatcg acaacatttg ttttggcagg tgaagaagct ggttctaaac ttactaaagc
    13201 aaatgattta ggaattaaag ttatagatga agagagattt ttagaattat taaagttatc
    13261 atcgaaagat gaagtaaaag ctgtattaga gagttaaaaa gtcgcttaat ttagtagaaa
    13321 actactataa ttaatgatag aatagttcag taagctaata agattacgaa aaatgacaat
    13381 aattaatatt tgacaaaatt aaaaattata aaaataaatt tataaaaaat aaaaaatatg
    13441 agaaaggata taaaaaatga ccagaagtta tgatagaagt aacgaacaga taagacctgt
    13501 aaagataact agagattata caaagtatgc agaaggttct gttcttatag aaatgggaga
    13561 gacaaaggtt atatgcactg catcagtgga agaaaaagtt cctccttttt taagaaatag
    13621 tggtactgga tggataaatg ctgaatattc tatgctacca agagcaacac aacaaagaaa
    13681 gataagagat gcatctaggg gaaaaattga tggaagaaca caagaaatac agaggttaat
    13741 aggaagagca ataaggtctg ttgtagactt gaataaatta ggagaaagaa ctatttgggt
    13801 agattgtgat gtgattcagg cagatggtgg aactagaact gcatctataa caggggcatt
    13861 tgtagcagtt gcagaagcaa tatataaatt atataaagca aagataataa aagagatgcc
    13921 aataacaaat tttgtgtctg caattagtgt tggtattgta aatggaatac acatgctaga
    13981 tttatgttat gaagaagatt ctaaagcaca ggtagatatg aatataataa tgactgataa
    14041 gtgtgagttt gtagaagtac aggggacagg agaagagaaa cctttttcga gagcagattt
    14101 aaatttattg ttagagttag gtgaaaaagg gaataaagaa ttaataaggc ttcaaagaga
    14161 agctttaggt gaaatatcag atgagatatt gggtatggat tatggtaatg aagtagtgat
    14221 tgctactaat aatgctcata agctagaaga aataggtgaa atcttaaaag attttgaata
    14281 taaagtgtac tctttaaaag atgttgattt agcaggtata gagatagtag aagatggaaa
    14341 aacatttgag cataatgcgt tgataaaagc tagaacaata gcaaaaaaga ctaaacttat
    14401 agcaatatca gatgattctg gcttagaagt agatgcttta ggcaaaaaac ctggtgttta
    14461 ttcagctaga tatgcaggag aacatgcaac agatgaagaa aatagaaaaa aactgttaaa
    14521 agctatgcaa aatataccaa tgagcaaaag aaatgcaaga ttcgtctctg caatagcagt
    14581 agtttttcct gatggaaaag aatttgtagt aagaggaatt tgtgaaggaa tgataggatt
    14641 tgaagaaaaa ggtaaaaatg gttttggata tgatagctta tttatagtaa aaggatatga
    14701 taagactttt ggtgaaatac ctagtgttat aaaaaattca atcagtcata gagcaaacgc
    14761 actaaaactt atgaaacaag agtttataaa aagggtagtg aagtaatgaa aataggcata
    14821 gtaagcgaca cacatatgat gattaaaaat atggaaaaaa caataccata tttgaaagaa
    14881 tgtgacctaa taattcatgc aggagataac tttactgatt caagatatat tcatagcatg
    14941 actaatgtag gtattattgc agttaaaggt aattgtgact ttgatgctgt tgaggaagaa
    15001 gttgtctttg aagtggcaaa taaaaccata ttcttatgcc atggagataa gtatggcgta
    15061 aaatatggaa ctcatatgtt agaaaaaaag gcaactgaag ttgatgctga tatagttata
    15121 tttggccata cccatacccc atttagagaa attaaagatg gtgtacttta cataaatcct
    15181 ggaagcactt cacttccaag aggagtatcg tataaaagtt ttgtcattat ggatatagaa
    15241 gaagatgaca taaaaattga agaaatacgc atataaaggt gtatttatct aaaaaaatgg
    15301 caaaaaacgc tcaaaaaatt aaattttatc aaataagtac aacgatatta atggaacact
    15361 tgtaaataaa aaaacttatg tgatataatt aagtggttga attataaata gaatgaatta
    15421 taataccgtt atcgggtatt acataaatat cactaggagg attagaagga tgaaagcaga
    15481 actaattaaa aaagagggta ataaagttac tttaaaaata acagtagata acaataaatt
    15541 tgaagcagca gtaaataagg cttataataa aagcagaaat aaatacaata tacctggatt
    15601 tagaaaaggt aaagctccaa gaattgttat agagactcaa tacggaaaag gtatattcta
    15661 caatgatgct atagaaatat tattcccaga agtttatcca gaagctatca aggaattaga
    15721 catagaccca atagacaatc cagatttaga tatagaagaa ataagtaaag acaatgggtt
    15781 ggttatggtt cttaatgtag aagttaaacc agagtttgaa ttaggaaact acaagggtat
    15841 agaaatagct aaggttgaga atactgtaag tgacgaaaat gttgatgcta aactacaaga
    15901 aatggttgaa aaaaatgcca gattagtaag tgtagaagac aaagctttag aagatggaga
    15961 tacagctata atagacttcg aaggttttga aaatggtgta gcttttgatg gtggtaaagg
    16021 tgaaaattat aacttagtta taggttcaaa cacatttata ccaggatttg aagaacaatt
    16081 agtaggtaaa aaagctggtg aagaagtaga agttaatgtt actttcccag aagaatatca
    16141 ctcacaagat ttagctggaa aaccagttgt atttaatgta aaaataaatg atgtaaaagt
    16201 aaaagaatta tctgcacttg atgatgaatt tgctaaagat actagtgaat ttgattcttt
    16261 agatgaatta aaagcagatg taagagctaa gttagaagaa gaagctaaaa atagagcaga
    16321 tgcagaaact agaaattcag tagtagaaaa agttgctgaa aatacagaaa tagaaatacc
    16381 agaagttatg atacaacatc aaatagataa tatgttaaat gaacttaact accaattaca
    16441 atatcaagga tttggattac aacaattact agagatgact ggtagaacta tggaagaatt
    16501 aagagaagag agaaaagaag atgctaaaaa attagttaag tcttctttag tattagaagc
    16561 aataactaaa gctgaaggaa ttgaagcaac agaagaagaa tttaaggctg agttagaaaa
    16621 aatggcttct gcttacaata tggaagtaga aaaaatagaa gcttctttaa gagatgccga
    16681 caaagaagat ataaaaggtc aaataaaaat aagaaaaaca atagatttat tagttgataa
    16741 tgcaacaata gcttaataaa ataaacgcta actaatatag ttgacgttat gaaatgttta
    16801 gtatataatg atgtgcaaat ataatttagt taaatgcgta taataattta cagtagctta
    16861 aaaaaagcta ctgtaaatta tatagaataa agggggtatg aaaccatggc attagtacct
    16921 gtagttgttg aacaaacagg aagaggagaa agatcttatg atattttttc tagactatta
    16981 aaagacagaa taatcttctt aggagatcaa gttaacgatg ccacagcagg gcttatagta
    17041 gcacagctat tatttttaga agctgaagac ccagacaaag atatacattt atatataaat
    17101 tctccaggag gaagtataac ttctggaatg gctatatatg atactatgca atacatcaaa
    17161 ccagatgtaa gtactatatg tataggtatg gctgcttcta tgggagcatt cttgttggca
    17221 gcaggagcaa aaggaaaaag actagcacta ccaaatagtg aaataatgat acatcaacca
    17281 ttaggtggag ctcaaggtca agcaacagat atagaaattc atgcaaagag aattttaaaa
    17341 ataaaagaaa ctttaaatga gatattatct gaaagaactg gtcagccatt agaaaaaatt
    17401 aaaatggata ctgaacgtga taacttcatg agtgcactag aagccaaaga atatggttta
    17461 atagatgaag tatttacaaa gagaccgtag atagagagag gtgttaatat gtctaaatat
    17521 gaagaaaaac gacaattaaa gtgttcattc tgcggtaaaa atcaagatca agtaagaaga
    17581 ttaattgcag gtccaaatgt atatatttgt gacgagtgtg ttgaactttg tgacgaaatt
    17641 attcaagaag agatagaaga tactatagat gaggatacta catctttacc aaaaccaaag
    17701 gaaatgatgg agattctaaa tgattatgta ataggtcaag aaaaagctaa aaaagcttta
    17761 tcagttgcgg tttataatca ttataagaga atatacagta aaaaatctag tagtaaggat
    17821 atagaaattc aaaagagtaa tatactttta ttaggaccta caggttctgg aaagacatta
    17881 cttgctcaaa ctctagcaag aactctaaat gtaccttttg caatggcaga tgctacatca
    17941 ttgactgaag ctggatatgt tggagaagac gttgaaaata tacttttaaa acttattcaa
    18001 gctgctgatt ttgatataga aaaagctgaa agaggtataa tatatataga tgagatagat
    18061 aagattgcaa gaaaatctga aaacccatct ataactagag atgttagtgg tgaaggtgtt
    18121 caacaagcac ttctaaaaat attagaaggt actgttgcaa atgttccacc acaaggagga
    18181 agaaaacatc ctcatcaaga atttttaaag atagatacta ctaatgtatt atttatatta
    18241 ggtggagctt ttgatggatt agagaagata attcaaaaac gtggtggaga taaaacacta
    18301 ggttttggag ctaaaataga aagtaaaaaa gaattagatt tagggaagct atatgaaaaa
    18361 gtacttccag aggatttatt aaaatatggt ataataccag agtttatagg aagaatacca
    18421 gttttagcta ctttagagtt gttggatgaa gatgcattaa tgcagatatt acaggaacct
    18481 aaaaatgctc tagtaaaaca gtataaaaag ttattggagt tagatgatgt tgagctagaa
    18541 tttgaagaag gtgctcttcg tgcaatcgct aaaaaggcca tagaaagaaa tacaggagct
    18601 agaggactta gaagtatagt tgaaagcgta atgatggaaa ctatgtttga agtaccatct
    18661 agagataata taaagaaggt tatagtaaca gagaaatctg tgaacgaaga ctcagtaaat
    18721 cctatcatag tacttaagga tcaagaggaa agtgcataag atgatgaaaa ggagctttaa
    18781 aagctccttt ttttatgtta atatgctaaa tataaaatag gtatcattat tataaaaatg
    18841 tgagtaatat acctagaata ccaaagacga atacaattgc aatggaacca atttttcctt
    18901 tatataaaag ataaaatgat gctataaatg caattattcc atataaatcc caattaactt
    18961 ctttggcaga tgaaaaagct gctgataata tgaatcctag agtaattggt ctaagaactg
    19021 tcaataagtt ttctaccttt ttattatttt taaatttaga aaataacttt gatataatag
    19081 ttagacctat taatgcaaaa attgtaacac caatagttgc ggctagagaa ccaaagaagc
    19141 cagcagtctt aaatcctaca aatgtagcac tatttattgc tacaggacct ggtgtagatt
    19201 gtgatatagc aagtaaatcc aaaaactctt gattagttat aaagtgatat ttagatataa
    19261 attcttgctg gataaatggt agcatggcat aaccgccacc aaaactaaat gcccctattt
    19321 taaggaatat taagaagagt agtattattt ctgacataga ctatatacac ctcctccaat
    19381 tattaaataa atagggctta tattgaatac accaacagat aaaactgcta taattaatag
    19441 tagtatgtta gttttagact ttggtagttt cttgaacatg ctcgtaaaag aatacaatat
    19501 aagagctatt acaacaggcg caactccttt aaaaaatcca tctaaaattt tagatgatga
    19561 atttttaaag tatagatacg ataagactaa gactatacaa aatgatggta aagcagagcc
    19621 taaggtacat ataagaactc ctggtatacc ataaagttta tatcctaata atacagatat
    19681 attaactgcc agtactccag gataactttg agctatggat aaataatcaa taaattcttc
    19741 ctgctctaaa agtttttgtt tgtttacaag ttcatcttgt ataagaggaa ccatagcgta
    19801 tccaccacca aatgtaaacg caccaatttt taaaaaggtt aaaaacaatt tcaacataat
    19861 agaaacctcc aaaagataaa taacatctaa gtatactaat attaatatta tatcataata
    19921 aaaagataat atagtatgat agtattctaa gaatttatca ttaatgttga aaattaactt
    19981 gttcaaatat ataatattaa aagcaaagca attagactag aaaaggagta atgttgatgg
    20041 aacaaaatta tactaaaata gatcatgaat taccattaat tcctctaaga ggattagcta
    20101 tatttccata tatgatatta aattttgata taggtagaga gatatctctt aaagctttag
    20161 accaagctat gatggatgaa gaacttatat ttttaacttc tcagaaagaa gcagaggtag
    20221 atgagccagg agaagaggat ttttatcatg tgggaacaat ctgtaaagtt aagcaaatga
    20281 taaaattacc aggagataca gttcgtgttt tggttgaagg tgtatcaagg ggtagagtaa
    20341 agaaaataga acaagaagat gggtatttca gagcagtaat agaagaaata gtatttgata
    20401 gtgataattt ggatagtgaa acagaagttg aaattgaagc atttgtaaga aatgtatttg
    20461 atgcctttga agagtatata aatattggaa atagggtatc accagaaata ttaatatctt
    20521 tagctgatat agaagatgta gatagattta tagatacgat agctgcaaac atatatctaa
    20581 aatcaagcca aaaacaagaa atattagaag aatttgatat tagaaaaaga cttgaactta
    20641 tttattctat attattagag gaaatagata tattaaaaat agaaaagaaa ataactttaa
    20701 gagtaaaaaa acagatgaat aaggttcaaa aagaatatta tcttagagaa caattaaaag
    20761 ctatacagaa agaattaggt gaagaagaag atataaactc tgaagcagat gagtatagag
    20821 aaaagcttaa aaaaataaaa gcacctaaga caactaaaga gaaaatagaa aaagagatag
    20881 ataaattttc aaaaatatct tctatgtctc cagatgtatc tgtaagtaga aactatttag
    20941 atactatatt ctcattgcca tggaataaag agacaaaaga taaattagat ataactaagg
    21001 caaaagatat attagatgaa gaccattatg gattagaaaa agttaaggag agaatactag
    21061 agtatctagc tataagaact cttgctaagt cacttaaagg gcctataata tgtctagttg
    21121 gtcctccagg aacaggaaag acatctatag taaaatcaat cgccagagca ttaaatagaa
    21181 aatttgtaag aatatctttg ggtggagtta gagatgaagc agaaataaga ggtcatagaa
    21241 gaacttatgt aggttcaatt ccaggaagaa taattaatgg ggtaaaagaa gcccaaacaa
    21301 aaaatcctgt attcttattt gatgagatag ataagatggc agcagattat aaaggtgacc
    21361 cagcttcagc aatgctagaa gtattagacc cagagcaaaa taaggatttt gtggaccatt
    21421 acttagaaat accttttgat ttatcaaaaa tactatttgt tacaacagca aatagtctaa
    21481 gtaatatacc aagaccatta ttagatagaa tggaagtaat agaagtatct ggatatatag
    21541 aagaagaaaa attaaatata gcaaaaaaat acctacttcc aaaacaaatt aaagaacatg
    21601 ctttaaaaga aaactttata aaaatagatg atgaaacttt aagaagtata atcaaccatt
    21661 atacaagaga agctggtgta agaacactag aaagaactat tggtaagatt tgtagaaagg
    21721 ttgccaaaaa atacgttgaa gacccaactc ttgaagaggt tgttataaat aagtctgacc
    21781 tagagacata tcttggaaaa gacatgttta agtatcaact tgcagaagtt aaccctcaaa
    21841 taggattagt aaatggtctt gcgtggacag aagttggtgg agttacactt gaagtagaag
    21901 taaacgtact taaaggtaaa ggcgaaattg tattaactgg aaaattagga gatgttatga
    21961 aggaatctgc gaagacaggt atctcttata taaggtcaat agtggacaag tttgatatag
    22021 accctgaatt ttataagacg aatgatattc atatacacat tccagaaggt gctgttccaa
    22081 aagatggacc atcagctggt ataactatgg ctcttgcagt aatctcagca cttactaaaa
    22141 gacctgtgcc tggaaatata gcaatgacag gagagataac tttaagaggt agagtcttag
    22201 cagtaggagg agttaaagaa aagttattag cagctcatag agctggtata acaaaagtat
    22261 taattcctaa agaatgtgaa gctgatttag atgaaatacc agaaaatgta aaagaaaaaa
    22321 tggagtttgt gcttgtagaa catatggatg aagtattaga acaagcttta ttaaagagtg
    22381 gtgaaaataa tgaaaattag aagttcagag ataactatga gtgctgtgaa taaatcacag
    22441 tatccagcag aaggaatccc agagatagca ttggctggta ggtcaaatgt tggaaaatca
    22501 tcaataataa atacattgct taacagaaga aactttgcta gaaccagtca aacaccagga
    22561 aaaactagaa ctataaattt ttatctaata aataatgaat tttattttgt agaccttcca
    22621 ggctatggat atgcaaagat agctaagtct gaaaaagaaa agtggggagg tataatggaa
    22681 cgatatctag aaagtagaca agagttatgt tctatattcc tacttgtaga tattagacat
    22741 gagcctacag cagatgataa gcttatgtat gaatggataa agcactttgg atataactgt
    22801 gtagttattg caactaaggc agataaaata tctagaggac aatatcaaaa acacataagt
    22861 ataataagaa aaaaattgca aatggaaagt agtgaaaaag taattcctgt ttcttcacta
    22921 aaaaagactg gtgttgaaga attatgggaa gagattgtaa atcaatacaa tcaacatgga
    22981 tatgaaataa cagtagatta aatttaaaat gttaaatatt gacataagat ttatttgaat
    23041 aataaatgta ataatagtta gttttaatta tattaatatt aaagtaaaat ataggatgcc
    23101 ttaaaatagt tttaatgaac ttttttttgg catccttatt gtttataaac aataaatatc
    23161 agtaattttg ctaaatacta ataaatttta gtaaggtatg ggaaaattag tataaaatag
    23221 ttaaactaaa aaattattga tttatgtagt cagtaataaa tagcatttaa gaaatagatt
    23281 tatctgtttt cctcataaag aaaacagtta gtataagccc tacaaaacat actgatgctg
    23341 caatccaata agactgattg ctagctataa cataggctga tgtgtgactt ttaaactttt
    23401 gattgtatgt aagactttgt gcaaaaaaac tactaaaaaa tgctgttcca agagcaaatg
    23461 ataaattacg aatagttgca agaaaactgc ctccgtaccc ctgtttttga ggaggaacat
    23521 ctgctaaaat actactattg tttggtgaac taaatgctcc tagcccaagt ccaaaaataa
    23581 ctaaacatac aattaaaagg tacaatggag aatctgcttt taaaagtgcc attccaacta
    23641 gtgagatggt cataaatgaa aaagatgctg ttagaatgtt ttttgcaccg tgtttatcag
    23701 aaagtgaacc tgcaataggt gctataagta ccataataag tggatgtaca gtcattacat
    23761 aaccagccat cataggagat aaatttttta attgttctaa ataaaatgga agtagaaaag
    23821 atactgccat ttgaggaaaa taacaagcta ctccaatgat attgcctaca gtaaagtttc
    23881 tatttttaaa tagagggagg tcaataaagc tttgttcaaa ttttacttct cttaatgcca
    23941 acaataagaa gattataagt gctgttatac ctaaatacaa tcttgtatta cccttctcat
    24001 tcattgcaag taatataagc gtagtgcaag atgcgaaaag tagaagacct ggaatatcaa
    24061 agctcttgtt ttgttcatcc aaaacaggtt taggcagaaa tttaatgcca agaaagactg
    24121 ctataatacc aatagggata ttgataataa aaatagaagg ccatccaaaa tgttctaaaa
    24181 ttatacctcc aattacagga ccactcatat ttcctatacc aactacagct ccagtgattc
    24241 ctatagcttt tcctttttca tttgctggaa atgcattgga aactatacca agcccagtag
    24301 ccattaaaat acttgctcca actgcctgaa agattcttga agaaattaat gttgataaat
    24361 tgtttgacat actacacaga aaagaaccta ttgtaaatat aaaaaatcct aatgtgtata
    24421 gacgatttga acctacttta tcgccaagtt ttccgaaaaa taacatagta gctgttacaa
    24481 caagcatata agctgttaca acccactgaa tttgtgacat gttaatttta aagtcagcag
    24541 caattgtagg atttgcgata tttagtatac ttccatcaag agtagacata aatacaccaa
    24601 tacagatgat aatcaatact atccattttt gtttcatgat aacactccaa tcttaataga
    24661 ttttataagt acgatataat tgtaaaataa acaacaaaaa aagcacctgt atattaggta
    24721 ccttgaatgt gtctaatttc atgaataaat acggtagttg aaggatttgt atagattact
    24781 catgtaaaat tacataaagg tactcatata ctattttctt ctaccatcca gattttactg
    24841 tcggctttgg aatatgacca aattatgcca taaggctcgc gggcttttac cgccgatagg
    24901 taatttcacc cgtttatgaa gaaaaacaga tgtattttgt aatattattt taacataaaa
    24961 ttataatgga aacaattgga tttaagtaat atccagctgt attacaatac aaatatttca
    25021 atatggacac ttaaattgta tttatagata gaataaggca cagtatgaga atctataata
    25081 attagataaa attaacctgt tattagtatt agatggcaag ttttaaattt gtcaaaatca
    25141 gaaagctgta ataaaattct tataatatga atatcttaat taagagatat tgtaaattat
    25201 gaggaggcgc taatatggaa ggaaaggtaa agaaggcatt cccgggtgga aatacatcac
    25261 aaggctcata ttcttttttt gactatataa ttcctgaaaa tgtaaaaaga gttttttgtt
    25321 taaagggtgg acctggagta ggaaaatcct cacttatgaa aaaaatttat aaagagtttt
    25381 tgcatagagg atatgatatt gatttatatc attgtccttc tgacccaagt tcgttggatg
    25441 gtttagttat aaagaaatta ggcgtggtac ttatggatgc aactgcccca catactatgg
    25501 acccaaagct acctggagct ttggatgaga taattaattt aggtgattac tggaatacag
    25561 aagaattaga aaagaataaa caagaaatat cagtttatga taaagatatt agtaattcat
    25621 ttaaaagagc atttaagttt ttaaaatcag cagaaccaat ctttagagac atagaagaaa
    25681 aatattctga ttgtatggat tatggcaaag taaatttggt cacagaagaa tttataaaaa
    25741 ggttatttga tggagttaaa agcacaggaa atctaaaaag agaaaagcat ttatttggtt
    25801 cagctataac tcctgtaggg tgtttagatt atacagaaaa cattttaaaa gatgtaaaga
    25861 aagtctatta tttagatgga gaaataggaa ctgggaaaac tacattatta aacaaagtat
    25921 ataagaaagc tattgaaaaa ggtttaaatg tagaagttta tcattatcca cttattccag
    25981 agaaaattga aactgtacta ttaactgatt tagatatagg cataactata agtacgactt
    26041 ttaaagaaga agatacaatt gatttaaatc agtttttaaa tagagaaaaa ctacttaaat
    26101 atgaagaaga tattaaattt gatgaaaaag ttttagatga tttaatttgt tgggcagtac
    26161 taaatcttaa gagagccaag tctaaacatg atattataga aagttactat agtcctaata
    26221 tgagatttga tgaagtaggg aaattaagag ataaattaat taaaagaatt ttaaaatatg
    26281 aggaaaactt ataaacgtat atgtttaaaa ttaatgttaa taatgatata atttttagta
    26341 aattggtgta gctttgaggc tatgccattt tacttttttt tgctaaaaaa tgatattaat
    26401 aatctccaaa gcaattattt gtttttcata attattattt cctttcctaa tttatgtttt
    26461 tttataatat caaaacaatg tttattgaaa gtttatataa ttttaagaac atctaaaaat
    26521 gcatacttga tattggtaaa ttagtgatag gagttcaatg tatgatatta tatactaaag
    26581 atgaatttta atatataact ttgatataat aagcatatgt aaatgtttaa tatttaatta
    26641 aagaaaatta tcatataaaa ataaatttgt aaggagcaat acagtatgaa aaaacaatat
    26701 gtgtttataa tactagcaag tactatttta ggtatacttg ttggaaccat atttagagat
    26761 tatagcaatg aagaaacagt ttatacaagc aaagacaagt caataagaaa agaaataaaa
    26821 atgacaagaa aatctataaa agaattaacc aaagagaaag acaagttaga taaagaaatt
    26881 aattcaatga aacaaaatca aaaaaattct gaagaaatat cagaaataga aacacttaga
    26941 gatagtctat catattcaga tgtaaagggt agtgggataa tattaagtat agatgctata
    27001 gatgaaaaaa cagggaatat agctaatagt atagactata ataagattct tgtaaaagtt
    27061 ataaatgaat taaaagtaaa cggaggaaaa tacatagaaa taaatggtca aagaattaat
    27121 caatattcag aagttgtact tgcaggaagc catataaata taaatggagt tcctgtagca
    27181 caaccatatg aaataaagtg cattggagat aaggagaaac tatctaatta tgtagataaa
    27241 ggtagtaaat atttagatag catacaaacc aattatccaa tgaaaataag cataaaaact
    27301 gaagaaaata tctctatgaa aaaaatgaat atacctaata aattaaagta tataaagggt
    27361 gattaagatt atattagagg aaagcagttt gccaatgtta ataccagaaa aacttgcaaa
    27421 aaaatataat gtatttccag ttgagtttca agatgataat ttagttgtag aaatagaaga
    27481 tgaggatatt tatgctctac aggacttgag attagctaca ggtaaagaaa ttatattgaa
    27541 gaaggagaaa aaagaactta taagtgaaaa gattgaaaaa tattataata gctttgaact
    27601 tgatgaggat tatgcaaaaa aattatttga aaatctttta gaaaaagcta taaaagaaaa
    27661 cgcaagtgat atacatatag aaccatttaa agaacattta atagtgagaa tgagggtaga
    27721 tggagaacta aaggaagtat caaagttttt agttgatgtc tatccatcat tgtctacggt
    27781 tataaaatta aaggcatcaa tggatataac agaaaaaagg cttcctcagg atggtagggt
    27841 ggatataaag ttaggtggaa atttaattga cattagagtt tcatcaatac caactgtcta
    27901 tggtgaaaaa atagttttga ggatacttaa tagagatact tttttaaaag acaaattaga
    27961 acttggtttt tcagaggaag ctataaaatc tataaatcgt ataataaata aaagagcagg
    28021 aatattatta gtgacaggtc ctacaggtag tggaaagact acaacagtat attccttatt
    28081 aaatgattta aaaggaataa ataaaaatat tatgactata gaaaatcctg tagagtataa
    28141 gatggatggc ataagtcaga ttcaagtaaa ttcaaaagta gggttgagct ttgatgtagg
    28201 tcttagagcg atattaagac aagacccaga tataataatg gtcggagaaa taagagatgc
    28261 agaaacagct aagatagcag taagagcagc tataacaggt catttagtta taagtacttt
    28321 acatactaat gatgcagtat cttccatagc tagattacta gaaatgcaaa taccaccata
    28381 tcttttaaat gcttctctta taggtgttat atctcaaaag ttggttagaa aagtctgcaa
    28441 tcattgtagc catgagatta tgataaaaga taattttagt ggagatgtaa atactaaggt
    28501 agctgtaggg tgtgaaaaat gtaatgataa aggatacttt ggaagaacag caatttatga
    28561 aatcttagaa attaatgatg atataaagac atgtataaga aatatggagg attctagtac
    28621 tattaaagat gtagcacaaa ataatggaat gataacattt gaagatagtt gtaaaagact
    28681 aataaatgaa aaaataacga cattagaaga gtgtttagta gtaaatgaaa tgatttaact
    28741 gaattgtata gttaaacttc gtttggtcag ttgtctttat ttaatctatt ttaattaaga
    28801 tgtttgagta taaattatat ttaagtgaaa taaaattaaa tgcattaaat tagaaaatat
    28861 taagtttatt taattgtaat taatataatt tggaaggtat tatagtacat gagattatct
    28921 aaaaatatat tttataattt agaaaagttt tatttagtat taaatagaat cagtgataaa
    28981 gaaattagag taatttgcaa agagataggc atattgctgg aatctggatg tgaaattaca
    29041 aaaatatttg aaatcattga gagtcagtca agtaaaaaag caaagaattt gcttagtata
    29101 gtatcaaatc atattcaaaa aggtaactca atagcagaat catttcaaat aacaggtata
    29161 ttttctaaat tctttataag tatgataaaa gcaggagaaa ctagtggaaa cttagatata
    29221 ataatgagtg atttatctaa ttattatgat aaagaataca aattaaaaat gaaaataata
    29281 actatttcaa tatatccaat aatacttata atattatcta tcttatcaat gttgtttata
    29341 ttcgtatttg taatacctaa ttttcaggtg gtttttacca acaatggaat tgaaccacct
    29401 ttaataacta gagttttaat gggaatatct acagtggtta caaataactt agcttatata
    29461 atatttagtt ttatattgtt ttcaatagga agcatttatt tctttataac aaatgataat
    29521 ataaaaaaat tgattaattc gttaaaattc aaaatacctt ttataaaaaa aattaatcag
    29581 ttagtagcta caacaagatt ttcaagggca ttgtccgttt taattagcag tggaatacaa
    29641 attgtggaag ctatagacat gtcagctagt gttatagaca acgaatttat ttatgaaagg
    29701 ttaaagattt ccaataatta tataaaaaaa ggaaatagca taggtaaatc tttgaattta
    29761 gcaaatgttt ttccaaaatt atttatttca atggcaaata caggagaaga aagtgggaaa
    29821 ctagataaaa gtctaaatgt aataaataaa ttttatgaaa atgaattaaa taacaaaata
    29881 gagcaaataa tgaaatttat agaacctatg ctaattgtat ttatgggatt aattattggt
    29941 acttttattt tagcaatggt tgttcctatg tttgatgcaa ttactaattt ttagagagaa
    30001 aaataaattt tattagatga aacttttgaa aaggagagaa tatttaattg ataaatttga
    30061 taaataaaaa acgaaaagga tttacacttg ttgaaatgat tgtagtagta actattttag
    30121 gcgttatatc tagtatagca ttagttaagt atagtaaggt tcaagaaagt gccaaattaa
    30181 atgcagacta tacgaatgct gctaatatag taaccgcagc tagcatggca attaatgatg
    30241 atgaaaagac aatagactct ctaagtgtag agacattgaa ggaaaaggga tacctaaata
    30301 ctgttccagt tcctcagagt acatcaggta aattcgaact tgtcataaat gatagcggaa
    30361 cagatataag cgtaaatata aattctaagc aattttatcc aaaataatat tttatattga
    30421 ttgctgtaag ttttaaaatt atttttattt aagaaggaga tggctataat taaaaaaatt
    30481 ctaaacttag aaataaatga tgattatata aggcttgtat ttttaagaaa aagtcataaa
    30541 aaagttttta tagataaatc aattataaaa gagattaact ttgatataaa aaatgatagt
    30601 aattcgattg agaagattaa atatatagaa gatgtagtta gatttgtaaa agaggagatt
    30661 ggtaaatcaa aaatattata taaaaattta tactttaaca ttcaaattca ggatatagtc
    30721 attagaaatg ttgaagttct aaatactaag aaaaaaagag acatattaag catgattgaa
    30781 tttgaaataa cacaatacat tccaataaac ataaataact attcaataaa atataaagtt
    30841 ataaattcta aaaatgataa attgaatata caagtaattc ttttcccaaa gagtattatt
    30901 caattaatta agaacatttc agaaaatcta aatatgaatc caaagactat aaatataaat
    30961 tttgatatat tacaaaagct tataaactta aatttaatag agaatttttc agaagaaggg
    31021 gtatttatag aatgtaaaaa aagtcagtta attataaata taacaaaaga taaaaaaata
    31081 agagaaacat acttgctatc aaaagaggga aaatcatatg agttcataaa aagattatta
    31141 agggatttta agtatgttta ttactatggt atagaaaatt gttttattga agaatacttt
    31201 aaatatacag ataaatctat tgaagtaaat ccattaagat taaaagataa agtaaaagta
    31261 gaaaataatt ttgatgcaga tttagaagac aataggataa attatataag taatatagga
    31321 atgattattt aagtgaaagt ggataaaacg ataaattttc ttaatggatt taaaaaaact
    31381 aaaccatgta ataaaatcta taaaataata atagtcttaa ttttaacgtg tattttattt
    31441 aaatcattta tgtatgtgaa atctataaat gaacttgaag attatataag tcaaaataag
    31501 ctagtggata aatcaagaca cactttacca acaacagata aaactagaga gaaattttct
    31561 aaaataaaac ttaatgaaat aaaaaaaata tatgaaacaa ttggaataaa tattattact
    31621 aaaatatcga tagataaaaa taagctagag attgaaggtg tgtgtagtga tttagatgtt
    31681 ttaaacaatc taaggaaaat aaagtacata aaatattatt acatagacag tattgtaaga
    31741 gatggagaat attatagatt tagaataaaa agttagatgg gtgattattt ttgagattaa
    31801 ataatagaga aaaaaatcta cttaaaatat tgttaatatt agttattata ttggcaagtg
    31861 atatagcagt aagttatttg gaagaaaact taactagttt gaagaatgaa aagcaaaata
    31921 taataaataa aataaataat caagataatt atcaaataaa ggataataag catatagatg
    31981 ataaatatat agaaagtgtt gaatcaaata aaaatgaaga attaaaaaat aattttaata
    32041 actcattttt agataaaaaa acaaataaag atatagtgtt attagtagaa aatgaactga
    32101 gagatattgt gaatgtagaa tatattaatc aagaaagtag tttagataat cacaataaaa
    32161 aacaagttaa tttagaaata aaagttaatg gagaacttgc aaatttgttg aaacttgaag
    32221 gtgtaatgaa gaagttaaga ctaaataata aacttgaaaa gatagaaatt aataaattaa
    32281 aagtcaataa ttttgatgtt caaaatattc caaatgaata taaacaagaa aaagacaata
    32341 ttgttgaatg taaaatgaca gttagagtca tataacaaaa aagaatagat aaagtaaaaa
    32401 actattatca attaataaaa ttttatagag gaattagttt tacgataatt catttctaca
    32461 agagggattg ttgatgattt tatcgaaatc ctaattaaag ttaatatatt gtaccaaaat
    32521 ataagtgaat ttaatagaat atttacttat actatagatt gattaataaa aaaatggtat
    32581 aataacaaat tgtactttaa tttaataata agggagtgga agtcatattg ttagggagaa
    32641 atgagctatg cccttgtgga agtggcaaaa aatacaagaa atgttgttta aataaagata
    32701 ttgtttcaga aagagcatgc agaaaaactg aactttcaca aaaacaatat acagatttat
    32761 attcaaagtt atatgattat tcaagacagg ataagtttaa agaagaatgt gaaaaagcta
    32821 aagaaatgtt ttatataatg caaaatgata gtgtaaatga aaaatttgaa agatttttta
    32881 atacttattt aatacaagac cacataatgg aaaataaaaa ggttatgaca gttggttttc
    32941 ttgaagaaaa tggtgcaaac ctaagtcaat cagaagtatc aatattaaaa agtatgtttg
    33001 aatcatacgt aagtatttat gaggtaaaag aagtttctgc tggaaaaata gtattaaagg
    33061 actgtttaag tggaaatgaa ctttgtacag aagatgtaaa acttctgaga agttttaaaa
    33121 tcggaagttg tatgatagct agaatagttg atattgaagg aactaacata ttgatagata
    33181 taactataag tatatcaaat gaggttaaag atataatttt aaaggatatt atgaatctat
    33241 tcaatcaata tcaagatgta tacaaagata tgaagtcgtt cttaatttat catacacata
    33301 tactatacaa gtatatacaa cagcttttag acccaagtat agctgaatat ttaaagagag
    33361 aaagagataa aaacgataca aaagttaatt cagaaaatga attagctgaa gaagaatgta
    33421 aagttttaga tactcttaaa gaaaatgtag aaaaagaaaa tatagatgca tgtatagagt
    33481 tttggaatga atataagaaa aatcatgaaa atataaaagg agctgaaaat ggttgggcag
    33541 ctgctgttga atactatgtt aaaaaagaag caggacaacc tataactcaa gttcaaatat
    33601 caaagaaata cgatataagc tctagtacac taggaaagag atacaaggat ttaaaaatat
    33661 cttaattaat tataaaaagc tttaagtcat agataaagaa tctatagtat aatatatgta
    33721 taatgtttag aaagaggtat taataatgag tcttagttta ggaaatgcaa ttgctgtatc
    33781 aacgaacttt ataaaatcta acccagctgt acctgtgtac aatggagaag aaatatatgc
    33841 agttatttat catatagaaa taggatataa taatggtgta tcacctgata ccaaacaata
    33901 tataataata gactataaag agtttgattt atctatggat aaaaaaaatg aactaataaa
    33961 tattgctaaa gagtactgta aatctaaagg tattgtagaa aacgaaaacc ttgaaataaa
    34021 ccttttagac aatgaagaag cagagaactt cttagaaaag gtgtttaata atatgaaggt
    34081 tataagaggt cttataacta aaaaaggata aataaatgga ctatatagga atagaaaata
    34141 taacacctta tgaaaataca tatgaattta gtgtatatga atatgatgat gaaatcacct
    34201 taggtagtga aaagttatat gtatgtgaat taagggttgt attgattaaa gttaattctc
    34261 tgtatgttga aagattgcat aaatcagttg aagcaatggt cttagtaaaa aacttgaaaa
    34321 aagatttaga taaaacactt gttgtaaaca aaataaagaa ttttgtgcta gatgagattt
    34381 gggtagaaaa tctagtaaaa gagaatatag aagttatatt tgtagaaagc taggaataac
    34441 cctagctttt ttatattaca atctaagaga ggaaaacaat atgttaagag tatctaatgt
    34501 aaaacttgga attgataaag atatatcttt attaaaagat gttatactta agaagctaaa
    34561 aataaaagaa aaaaacttag tcaaatatag tatatataaa gaatctatag atgctagaaa
    34621 aaaaggaaaa atggaatttg tttattctgt agatgtagaa gttaaagatg aaaataaaat
    34681 acttaactca aaaataaaag atgtaacaaa aataaaggaa atcagatacg taaatgtacc
    34741 tgtgggtgat aaaaaattaa agaataatcc tttggtaatt ggtagtggac cagctggttt
    34801 gtttgcaggt ctgcttttag ctcaaatggg ttatgaacca atcatacttg aaagaggtct
    34861 tgatgtagac agtagaacca aagatataag tgatttttgg acaactagaa aattaaaaaa
    34921 taattcaaac gttcaatttg gagaaggtgg agcaggaact ttttcggatg gtaaacttac
    34981 aactagaata aaagatatac gatgtagaaa agtattagaa gagttagttc agtttggggc
    35041 accagatgaa atattatact cacataagcc acatgttgga acagatatat taaaaaatgt
    35101 agttaaaaat ataagaaatg aaataataag tttaggtggt caagttagat ttaattcaaa
    35161 agtaacagat atagttgtat caaatgattc tatacaatct gtaataataa atgatactga
    35221 aaaaatagat acagatacaa ttatattagc tgttggacat agtgcaagag atacttatga
    35281 aatgttgtat tcaagaggta taaaaatagt tcaaaaacct tttgcaatag gagctagagt
    35341 tgaacatcca caagatttaa taaataaagc acagtacaag gatttttata atcaccctag
    35401 gttaggagct gcagattata gacttataga gcatgtttca aatggaagaa cagcatatac
    35461 tttttgtatg tgtccaggag gtagtgtcat agcatctgca tcaaatgatt ttgaaatagt
    35521 tacaaatggt atgagtgaac atgcaagaga taaaataaat gcaaatagtg catttttagt
    35581 aaatgtaacg ccagaagatt ttaagagtga taatccacta gcaggtgttc atttccagca
    35641 gaagtatgaa aaattagctt ttgaattagg tggaaaaaat tataatgcac cagttcagct
    35701 tgttggagat tttataaaca ataagacttc tttgaattta ggaagtgttg agccatcata
    35761 tagaccagga tatacactta caaatttaag tgaatgtttg cctagcttcg taacagagac
    35821 tatgagagaa gcgtttatat ctcttgataa aaaattgaat gggtttgcaa tgtatgatgc
    35881 tgttttgacg ggagtagaaa ctaggtcatc atcaccaata agaatagtga gagatgaaaa
    35941 tactttagaa tcagtgagta ttaagaatct atatccatgt ggtgaaggtg ctggatatgc
    36001 aggtggtata gttacagcag cagttgatgg tataaaatgt gcagaaaaaa taatacaaaa
    36061 atacaccaat aatacaaaaa tttaacataa acttaatgat tttttaatat ttaacatgaa
    36121 tttaacatta tcactcctat aatttgataa aatacaatag gttataaaat ttttagatac
    36181 agtaatctct ttacaaggag gaaataattt gaacattata ataagtctaa tgggtggatt
    36241 aggtctgttc ttatatggta tgaaccttat gggagaaggt cttcaaaaat ctgctgggac
    36301 aaagctaaaa aagataataa aactacttac tagtaaccta tttatgggag ttttggtagg
    36361 tacaggagtt acagcagtaa tacaaagttc aagtgctact actgtaatgg ttgttggttt
    36421 cgtaaatgca ggaataatga ctttaaaaca ggcaatagga gttataatgg gtgctaatat
    36481 agggactact gttacagccc aattggtatc tttcgactta actggtatgg ccccagtagc
    36541 attaggtgta ggtattatac tttatttatt tggaaataag cctagaataa aaaatatagc
    36601 cgaaatactt ataggttttg gtatattatt tacaggtatg gattttatga agatggcagt
    36661 ggagccacta agagactatc aaggatttac tgacttactt gttacatttg gtagatatcc
    36721 actacttgga ttattattgg gatttgggat tacagcaata atacaaagtt caagtgcatc
    36781 tatgggtatg ttggttgcac tggcagcaga aggtctagtg ccactatcag cagcactgcc
    36841 aattctttat ggccaaaata ttggtacatg tgtaacttca ctgttatcaa gtattggtgc
    36901 taacaaaaat gcacgaagag cagctatgat gcatctaatc ttcaatgttt taggaacggt
    36961 gatattctta atattcttga ataaaccagt agtaagcatg gttacaagtt gggatccaag
    37021 caatgttgca agacaaatag ccaatacaca tacattgttt aatataatat ctgtattgat
    37081 acttttacca tttacaagtc ttattataaa actagctata aagcttgttc ctgatagagc
    37141 aggtgatata gatgaagatg aaactaaaac tattaaatat atagatgata gaatgataga
    37201 aactccttct atagctcttg caaatacgat aaaagaagca cttcgtatgg gtgagaaggc
    37261 gaaggaaagc ctaaatgcat ctatggaagc tttagtagaa cattcaactg aaaaaataga
    37321 taagacatat agacgagaga gattaatcaa tgatttacag aaagctattt taaattattt
    37381 acttaaactt tcaaaagcag ctttagatga tgattcaaga gaagttgtgg atactttgtt
    37441 taatacagtc aatgatatag aaagaattgg tgaccacgct aaaaatatag ctgaattatc
    37501 acaagttgca atagattcaa atatttattt ctcagaagaa ggacaatctg aacttgatgt
    37561 tatgtataat agagttgttt cagcatatac ttatgcatta gaatcaatga ggagcgataa
    37621 tgttgattta gcttgcaagg ttataaaaat tgaagaacaa gttgatataa tggagaaatc
    37681 ttgtagagct aatcacatgt atagattgaa taataatcta tgtagtatag aaaatggagt
    37741 tatttattta gatgtaataa gtaatttaga gagaatatct gaccatgctg tcaatatagc
    37801 acaacaagtt atagcgaaga gattaggaaa tgattaaaaa taattaattt aaaataatat
    37861 aaaatttaaa atagaggata aataaaagag aaactttaaa tgatacgttt agagtttctt
    37921 tttttgtaaa tttatttgac taaaattttt aaatttatac atagttatag tatttagaag
    37981 aatcgatttc ctgataataa atgatgagat atgtatgatt ttgtggcaaa cttttaaaaa
    38041 aaacacctat attttgtgtt ataatctctt taaaacgaat atgctgaaaa gagggattta
    38101 aatgggaaaa ataaattttg attatagtaa agctacagag tttttttgtc aaaacgaaat
    38161 agatgtcatg caaccatatg tagatgttgc gcacgacatg ttacataata aaactggttt
    38221 aggaaatact tttttaggat ggatagacct tcctaaaaat tatgataaag aagagtttga
    38281 cagaataaaa aaatctgctg ataagataaa atcagactca gatgttcttt tggtaatagg
    38341 tataggaggc tcttatttag gttcgagagc tgctatagat atggtaagtc attcttttag
    38401 gaatggactt aaaaaagagc aaagaaaggc tccagaagta tattttgtag ggcataatat
    38461 aagctcaaca tatattatgg atttattaga tataattgaa ggaaaggata tttctgtaaa
    38521 tgtaatatct aaatcaggaa ctactacaga accagctctg gcttttagaa tatttaaaga
    38581 ttacttagag aaaaagtatg gtaaggaaga agcaagaaag agaatttatg caacaacaga
    38641 tgcaagtaaa ggtgcactta gacagttagc tacagaagaa ggatatgaga cttttgtaat
    38701 accagatgat gtaggtggtc gtttttctgt attgacagca gttggattac ttcctattgc
    38761 tgctgctgga cttgatattg atgctatgat gaaaggcgca aatgatgcta gagaagcatt
    38821 tcaaaatcct gacttaaaaa gtaatgatag ttatagatat gctgttgcta gaacaatttt
    38881 acatagaaaa ggaaaagatg tagagttatt agtgaactat gaacctcaac tacattatgt
    38941 aagtgagtgg tggaaacagc tttatggaga aagtgaagga aaagaaaata aaggtttatt
    39001 ccctgcttct gtagatttct caacagattt acattctatg ggtcaataca tacaagatgg
    39061 aaaaaggctt ttatttgaga cagtacttaa tgttgaaaac tgtaagagaa atataactat
    39121 aagttcagag gaagtagact tagatggttt aaattattta gcaggtaaga ctgtagattt
    39181 tgtaaatcat aaagcttttg aaggaactct attggctcat acagatggaa aagtacctaa
    39241 tttagtaata aatatacctc aactagatga gtataatttt ggatatttag tttatttctt
    39301 tgagaaggct tgtggaataa gtggatattt attgggagtt aatccatttg accaaccagg
    39361 agtagaagct tacaagaaaa atatgtttgc tttactaggc aaaccaggtt atgaaaaaga
    39421 aaaggaagag ctagaaaaaa gacttaaata attttaaata gttaaggttt aattaagatt
    39481 aaaataatat aatgaaatca tcaaaaagga gtttactcaa aatagatgat ttcatttttt
    39541 ttatgaaaaa ttgggaaaaa tatattttga taatttatat tatattaaga tagggagtgg
    39601 tatgagatgt caagaagaaa gaaagggata agtttagtaa tattagttgc tataataagt
    39661 tcaatactta gtagttttct aacaataatt ttagttaagg acaatttagt aagcaaatct
    39721 acaggaagtt ctacgccgat agttgtaaat gatgatggta agagtcaaaa tatttatcaa
    39781 gcagttgcag aaaaagctac gccatctgtt gtaggtatta caacaactag tgttgatact
    39841 agtaatatgt ttgcaatacc aactgaaaca caaggtgtag gaactggaat catagttgat
    39901 tcaaatggat atatacttac taattctcat gttatatcag atggtcaagc tacaagtgta
    39961 aatgtattat tcaatgatgg ttcaacaact tcaggtaaag tagtatggtt tgaccaacaa
    40021 cttgatttag ctatagttaa ggttgataaa actggactaa caccagcaga atttgctgat
    40081 agtgacaaag taaaagttgg agatatatca atagcaatag gtaatcctct tggattagat
    40141 tttcaaaaaa cagttactca agggataata agtggattag atagaactat acaaacagaa
    40201 aaaactaata tgactggttt attacaaact gatgcaagta taaatgcagg aaatagtgga
    40261 ggaccattgt taaatcaaaa aggtcaagta attggtataa acacagcaaa agcttctcaa
    40321 gcagaaggat taggatttgc aataccaatc aatacagcta agagtatagt tgaagaagta
    40381 atcaaaaatg gaaaatatga aaaagtaact ttaggcataa aaggtacaga tgtatcaaat
    40441 tatgaagcag caacaggtac aaaattaagt actgataaag gtgtttatgt tgcagaagta
    40501 atatctggtt catcagcaga aaaagctgga gtaaaggtag gggatattat aactaaagta
    40561 ggagatacag atataacagg tatgaatgat ttaaataaaa agttgtatac tttctcaaaa
    40621 ggtgctagta caaaaataac agtaaataga ggcggaaaag cagtaacaat aaatgtgaat
    40681 ttctaaatat gaccaaaaag atagagacta catggtaaag tgtagtctct atttttattt
    40741 aatttttata gtatatacat ctaaattaat taaaatgatg tattgtttat agtttattgc
    40801 tatattttct tataaaaata aatttaataa atatttaaat ttaatttaca aaaacaatat
    40861 aaatatcata ataaaataaa attttttaat attactaaaa atatatagac aaaataataa
    40921 caaatatagt attatgtaat tgtagaaatg cttttcatag gtatattcta tgaagatgaa
    40981 ttgcataaaa atgaaaaaat ggaatggata ttatttaggg gtgaaaaatc atgaatccat
    41041 tagttataaa cttacaaaaa tgtagcatac atgatggacc agggataaga agtacagtat
    41101 tttttaaagg gtgtccactt gaatgtgttt ggtgtcataa tccagagagt caaacatata
    41161 caaaacaagt tttgtataat gaagaaagat gttcaaaatg tgaagcatgt ataaatatat
    41221 gccctcataa ggcaatttac aaaggtgaaa caaaaatatg cttagaccaa gataagtgtg
    41281 agttttgtga aacttgctta gactattgtg taaacaatgc aagagagatt gttggtcaag
    41341 agtattctgt aagagatttg gttaaagaga tagagaagga tagaattttc tatgaagaat
    41401 caggtggtgg agtaactcta tcaggtggag aagtaatggc tcaagatatg gacttcattt
    41461 gtggagtaat aaacatgtgc aaatcaaagg gaatccatgt agcaattgat acatgtggct
    41521 atgcaaagtc agaaaattat gaaagagttg ctaaatgtgc agatttgttt ttatatgata
    41581 ttaagcttat tgatgaagat aagcacataa aatttacagg aaaatcaaat gacttaatac
    41641 tgaaaaatgt taagatttta agtgaattag gggctaacat aaatataaga ataccattaa
    41701 ttgtaggagt aaatgtagat gatgaaaatt tagaggttaa aaaaatgata gagtttttaa
    41761 agcctttgaa tatacaagca gtaagtcttc ttccatatca taatattggt aaacacaagt
    41821 atgataaaat ttataaaaag tatgaaggag aagaactaca aagaccatca gaagaaaaat
    41881 tagaggaaat aaaaagactg tttgaagcaa gtaatttcaa tactaagatt ggagggtaat
    41941 aaaatggcaa gaggaacttt tgagagaact aaaaaattaa gagaagaaag tattaatgca
    42001 gaaccacaca tatctattga aagagcagta cttatgacag aagcttataa aaaatatgag
    42061 ggaagtgtag agattcctgt acttcgtgct ttatcattta agcattatat tgagaataga
    42121 actcttagca taaatgatgg agaattaata gtaggtgaaa aaggtgattc tcctaatgga
    42181 gcaccaacat atccagaaat ttgttgtcat acaatggaag atttagaagt aatgcacaat
    42241 agagatataa taaattttag cgtatcagaa gaagctagaa aaatacataa agaagaaata
    42301 attccttttt ggaaaaagag acaaacaaga gataagataa taaatgcaat gacacctgag
    42361 tggttagcag catatgaagc aggtatgttt acagagttta tggaacaaag agccccagga
    42421 catacagttt gtggagatac aatatataaa aaaggatttt tagatttaaa gaaagacata
    42481 gaagcaagat taaaagagct agattttctt aatgatttag atgcatataa taaaaaagca
    42541 gatttagaag ctatggcaat agcttgtgat gcaatggtta tattaggtaa aagatatgct
    42601 gagaaagcaa gacaaatggc agaagaagaa acagatgaag ctaagaaaca agatttatta
    42661 ctaattgctg aaacttgtga tgttgtacca gctcacaaac cagaaactta tcatcaagct
    42721 atacaaatgt attggtttgt tcatataggg gttactactg aacttaatat atgggatgct
    42781 tttactccag gaagacttga ccaacatcta aatcctttct atgaaagaga tgtagaaaat
    42841 ggaatactag atagagatag agcacaagaa ttacttgaat gtttatgggt taaatttaac
    42901 aatcagccag caccaccaaa agttggtata acattaaaag aaagtagcac atatacagat
    42961 tttgcaaata taaacactgg tggaataaat ccagatggtc aagatggtgt taatgaagtt
    43021 agttatataa tacttgatgt tatggatgaa atgaaattga tacaacctag ttcaaatgtt
    43081 caaataagta aaaagactcc tcaaaaattc ttaaagagag cttgtgaaat atcaagaaaa
    43141 ggatggggtc aaccagcatt ttataatact gaagcaatag ttcaagagct tatggaagct
    43201 ggaaaaacta tagaagatgc aagacttggt ggaaccagtg gttgtgttga aactggatgt
    43261 tttggtaaag aagcatatgt tctaactgga tatatgaaca ttccaaaaat acttgaatta
    43321 acattaaata atggatatga cccaattagt aaaaaacaaa taggtattga aactggagac
    43381 cctagaaatt tccaatctta tgaggaacta tttgaagcat ttaaaaagca attacattat
    43441 atgattgaca taaaaataga aggaaatgct gtgatagaaa atatatgtgc aaaacacatg
    43501 ccttgtccac ttatgtctac aatagttgat gattgtatag aaaaaggcaa ggattaccaa
    43561 agaggtggag caagatacaa cactagatat atacaaggtg ttggtatagg aactataaca
    43621 gatagtttaa cagcaataaa atataatgta tttgataaga aaaaattcga tatggataca
    43681 ttgcttaaag cacttgatgc taattttgaa ggatatgaag ctatacttaa tttagtttca
    43741 aataagactc ctaaatatgg aaatgatgat gattatgctg atgaaataat gcaagagata
    43801 ttcaatgcat attacaatga ggtaactggt agaccaactg tttgtggtgg agaatacaga
    43861 gtagatatgt taccaacaac ttgtcatata tactttggag aaattatggg agcaagtcca
    43921 aatggtagac tttgtgcaaa accagtttca gagggaattt cacctgaaaa aggtggagat
    43981 actaatggac ctacagcagt tataaaatct tgtgctaaga tggaccacat aaaaactggt
    44041 ggaacattat taaatcaaag atttgcacca tcagtagttc aaggagaaaa agggttagat
    44101 aatatggcta atctagtaag agcatacttt aatatggatg gtcatcatat acaatttaat
    44161 gtatttgata aaaatgtact gttagaggct caaaagaatc ctcaggatta taaagactta
    44221 atagttagag ttgcaggata tagtgaccat ttcaataatt taagtagaac actacaagat
    44281 gagataatag gaagaactga gcaaacattc taggtttgct tgtaaataaa acttcttact
    44341 atataaaatc gtaactgata taataaagta taaatggttt gattccattt ttaaaatttt
    44401 agattaatta tgagctaact ttctaaatag gaagttagct cgttaagttt aatgaaaaaa
    44461 tcgttaaatt tatatttagt aaatcataca catattagta agtaatacat acaaaagaat
    44521 aatttattat agttataata aggttatatt ttataaaaat aagataattt taagcagtta
    44581 aaataaagtc aatttagcta ctttaaaata aaactaatag aaaaaaggag atttgatatg
    44641 aaaactttag gatttattgg ttcagggaat atgggaagtg caatgatagg tggcatagta
    44701 cagtcaggat tagtaaaggc agaagatata actgtatcag atttaagcca agttgcctta
    44761 gataaagtaa aagaagaatt tggagtaaat actacaactg attcaaaggt agctgttaca
    44821 aattctgatg tggtaatagt agcacttaaa cctaatatat gcgaaaaggc tttaactcca
    44881 cttaaagaat taatagatgc aaataaaata atagtatcta tagcagcagg taaaactata
    44941 gaaagtctgg aaagttttat aggttcagat aaaaaaatag taagagtaat gcctaatact
    45001 ccagcccttg ttggcgaagg aatgtcagct ctttgtaaaa atagtaatgt aacagatgaa
    45061 gagttaaata tgattaaggc tctgtttgaa tcttttggtg aggcagaaat agtatcagaa
    45121 tatttaatgg atacagttac aggtattagt ggttcttctc ctgcatatgt atttatgttt
    45181 atagaagcta tggcagatgc agcagtatta gctggaatgc caagacaaca agcttataaa
    45241 tttgcatctc aagcagtaat ggggtcagct aagatggttc ttgaaactgg aaaacatcca
    45301 ggtgaattaa aagatatggt ttgttctcca gcaggaacta ctatagaagc tgttaaggta
    45361 ttagaagaag aaggctttag agcagcagtt ataaaatcta ttgttgcttg tatagataag
    45421 tctaaagata tgagtaaata acagatgtaa ttaagtttac tatatggttt cttgaattgt
    45481 ttttttagtg cttatttata tctatacata aatgtatttg gtataagtaa aataagagta
    45541 atttactata aaaaggaatt taatgattga gtga
//
LOCUS       DAMJVG010000027        43698 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.027, whole genome shotgun sequence.
ACCESSION   DAMJVG010000027 DAMJVG010000000
VERSION     DAMJVG010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 43698)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43698)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43698
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.027"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            94..996
                     /locus_tag="PC512_001594"
     CDS             94..996
                     /locus_tag="PC512_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDF2441340.1"
                     /translation="MFKKNKKQTENVKEKKVRTVKVGTHKKTVIALWVVLIASVSFGV
                     YKNFTAIDQHTTHEKEVIELRLQDTNGIENFVKNFAKSYYTWSNSKEAIDARTQAISG
                     YLTKELQDLNMDTIRTDIPTSSAITDVIVWSIEQSGTDTFSATYEVDQQIKEGEQTTA
                     VKATYTVKVHVDAGGNMVIIQNPTLAPAIEKSDYEPKTPEADASVDADTINDATAFLE
                     TFFKLYPTATEKELAYYVSGNVLESIGRDYLYSELVNPIFTVDGDNVKVKVAVKFIDN
                     QTKATQVSQFELVLHKESNWKIIG"
     gene            complement(1195..1530)
                     /locus_tag="PC512_001595"
     CDS             complement(1195..1530)
                     /locus_tag="PC512_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441341.1"
                     /translation="MTHMSADKLLLGFHLDHVSNLNELLRKVAHNNICIMSDRMTKVA
                     VWKPSVKTIQLVCMEYLNYIIDHSVIYEKIQCANWNGTEETNSIFNNSPSPLITLIYS
                     CDLQQNKTT"
     gene            1480..1689
                     /locus_tag="PC512_001596"
     CDS             1480..1689
                     /locus_tag="PC512_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441342.1"
                     /translation="MVKVKTKKKFVSTHMCQGEMPIYVRERYEKMLAVSIRAPNLEGM
                     VENFDKDLSRPNETDLIELKNAISK"
     gene            1782..4445
                     /gene="mgtA"
                     /locus_tag="PC512_001597"
     CDS             1782..4445
                     /gene="mgtA"
                     /locus_tag="PC512_001597"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016440611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HDF2441343.1"
                     /translation="MSKATLFDSRIKKYAYCRTSEIYRDIGSSPDGLSIEQIGSMREK
                     YGANSFNGRKNDTTMQRLRRAFINPFHVILFVLGIVSLVTDVFVASNFARNATTAIII
                     FSMIVISGVIRLIQELRAKSAAAQLDRLVHESVTVRRDGKLIEIPGEELVVGDIVLFS
                     AGDRVPADIRLTKITDLFISQAAITGESAIIEKSCRKLSYGEQDTLTQLENLAFMATT
                     VISGKGEGIVLAVGKDTLYGGFTKPDSDDKNSFKKGADSIAWVMIRFMAILVPIVFIL
                     LGITDGKWMESFAFALSVAVGLMPEMLPMVITACLAKGSLAMSKKQTIIKDINAMQSF
                     GSMDVLCMDKTGTLTNESILLEYYMDIFGNENAEVLDLAYLNSCYHSGVCNTIDNAIL
                     ACNTMPGREAHYANLLTKFQKADEIPFDYARKFVSTLVQDSNGNSQLIMKGDIEHIFS
                     RCNHVEYRGKLLPMGQDARQSVSSVVGEMLQDGMKVIAVARKNVGAQKKITPDDEWGM
                     TLVGYLSFFDAPKQTAKESVTALKRLKVIPKILTGDQAAIAVSVCRRVGIYTERILTG
                     TQLDEMTDCELKKAVEHTHVFAELTPGHKVRLVSAMQDNGHSVGFLGDGVNDIPALNE
                     ANVGISVDTAVDAAKDAADVVLLQKDLNVLEQGVMEGRKTFTNMLKYIKITASSNFGN
                     IFSIICASAFLPFLPMTSIQILLLNLLYDTLCIVLPWDNVDEEEMLSPRDWSGKTLRQ
                     FMLSFGPISSLFDIVTFLFLYYFLCPMLCGGATYLQLTDPSLQLQYVALFQTGWFLES
                     MWTQVLILHFLRTSKIPFFQSRASAPVISITLVGIIAFTSLTFVGGASLFGLTKLPLW
                     YFVFLLLVVSLYMLLNSVAKYFYKKKYQELI"
     gene            4461..4964
                     /locus_tag="PC512_001598"
     CDS             4461..4964
                     /locus_tag="PC512_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006566797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDF2441344.1"
                     /translation="MKKNISYIPMDSALEIWLLEKLLRDPPDSDCAKDLLSGIQEMIR
                     GEVSSLLLGASEESDWPVGTLSDRILAGDLEIYPRGRKVLIKGSEVNLTPKEFDILYF
                     LVQNKGEVFTKEQIYRAVWEEDYILDNSNIMAFIRKLRKKIEPAPDCPTYILTIWGIG
                     YKFNDQI"
     gene            5102..5779
                     /locus_tag="PC512_001599"
     CDS             5102..5779
                     /locus_tag="PC512_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018597221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HDF2441345.1"
                     /translation="MFYTDFILRIALSLTLGFLIGLERQLTGHPAGIRINVLICMGTS
                     FFTLFPMLYGSDQVFRVGSSIISGVGFLCSGVIFKDRGTVRGMNTAATLWCTAAIGIL
                     ASTGMYAMAITAATILIGSNLILRPFARKFHPITSSDESEKQYRISVTCQEKAEQDIR
                     LLLINSNSCKTLFLNNLESGDVVGDKVEIVAEYCSVGKSKNNILEGIVGQVLVIPEVI
                     SAGWEVL"
     gene            6026..6337
                     /locus_tag="PC512_001600"
     CDS             6026..6337
                     /locus_tag="PC512_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3784 domain-containing protein"
                     /protein_id="HDF2441346.1"
                     /translation="MDFTCIFFGILFTLAGFWLAFGKGYRHLSLWKNMPQEEKDKINI
                     VPLCRNVGEMIALNGIIFLMKGFLPGFSNHWFVFAIIAWLIVAGFDVWYIEKSVRYRN
                     Q"
     gene            6503..9268
                     /gene="mgtA"
                     /locus_tag="PC512_001601"
     CDS             6503..9268
                     /gene="mgtA"
                     /locus_tag="PC512_001601"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002571344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HDF2441347.1"
                     /translation="MNKKENRMAIRQTVEKAVIRDEQNRRIQFAATNPIKEVLKKLHT
                     TLRGLEVDEVSVSRAKYGTNKVTHEKKKSLAKRLVGAFINPFTAILFCLALVSTITDM
                     IFPYFSLFGSVPEDFDSLTVVIILTMVFISGTLRFVQESRSGNAAEKLLAMITTTCTV
                     TRRNYEKKELPMDDLVVGDIVHLSAGDMIPADVRILDAKDLFVSQASLTGESEPIEKT
                     PNVSAQKESVTDYTNIAFMGSNVISGSATAVVVCVGDHTLFGSMASAVAGEAVETSFT
                     KGVNAVSWVLIRFMLIMVPLVFFVNGITKGDWLAAFLFGVSIAVGLTPEMLPMIVTTC
                     LAKGAVSMSKKQTIVKNLNSIQNFGAIDILCTDKTGTLTQDKVVLEYHLNVNGEDDTR
                     VLRHAYLNSYFQTGYKNLMDLAIIHKTEEEEAADSRLIDLSENYVKVDEIPFDFTRRR
                     LTTVVQDNKGKTQMVTKGAVEEMLSICAFAECNGGVQPLTDDVRYRILETVDNLNDKG
                     FRVLAIAQKSNPSPIGAFGVKDECDMVLIGYLAFLDPPKESTADAIKALKDHGVITKI
                     LTGDNDKVTRTICKQVGLEVRNMLLGSDLEQMGDAELARVAESTDVFAKLTPDQKARV
                     VSVLRENGHTVGFMGDGINDAAAMKAADIGISVDTAVDVAKESADIILLEKDLMVLEQ
                     GIIEGRKTYANMIKYIKMTASSNFGNMFSVLAASALLPFLPMMSVHLIFLNLIYDLSC
                     TAIPWDNVDEEFITKPRKWDASSVGSFMIWIGPTSSIFDFTTYIFMYFVFCPLFVSNG
                     VLFNDLPAHFSGAELAMLQAQYIGMFQAGWFVESMWSQTLVIHMIRTPKLPFVQSRAS
                     APVTLLTMTGIIVLTIIPFTVFGTMLGFVALPAAYFAYLIPCILLYMTLATSLKKAYV
                     RHFGELL"
     gene            9281..9448
                     /locus_tag="PC512_001602"
     CDS             9281..9448
                     /locus_tag="PC512_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002587909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441348.1"
                     /translation="MNWKELWMTLFGTTEWLGLNIGFWVAMAVVLLIVIVMNVVFWSM
                     KPKKDTKESYK"
     gene            10499..10798
                     /locus_tag="PC512_001603"
     CDS             10499..10798
                     /locus_tag="PC512_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDF2441349.1"
                     /translation="MKHLHIQQLSTIGSSLKKHLNSTEHNAPICGFLQHITGIICLAQ
                     DQYVCIALVLFYCIKLFQKIFAVGYQIPPFMVSVSAKRGRSLFALATFAGKGVRL"
     gene            10795..11211
                     /locus_tag="PC512_001604"
     CDS             10795..11211
                     /locus_tag="PC512_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002592281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF2441350.1"
                     /translation="MKPSSFEGAIRLQFDCLARKVVGRTVKNYDRELGRRARRETPFC
                     DLSEMELNQIGAMDEYCVEFTSFDVFGSEVHIYDERLCEAIKELTESRRNILLMSYFL
                     EMTDAEIAEVMEMERFSVCRNRLHTLKLIKDMYEEE"
     gene            11216..11455
                     /locus_tag="PC512_001605"
     CDS             11216..11455
                     /locus_tag="PC512_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002592280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2441351.1"
                     /translation="MMKSTKKCPSFSTISSAADGNEVAIEKILNHYDAYISKASLRPF
                     YDEHGNMYIVLDMELKGRIRAALIKVILGFEVKVK"
     gene            11774..11917
                     /locus_tag="PC512_001606"
     CDS             11774..11917
                     /locus_tag="PC512_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDF2441352.1"
                     /translation="MNNIIRYSMQIAMLKQLLARKLISEKEYTLVKQRLMKDYKVLSD
                     ITA"
     gene            11980..13740
                     /locus_tag="PC512_001607"
     CDS             11980..13740
                     /locus_tag="PC512_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDF2441353.1"
                     /translation="MQEVEVIKAKNVLARQARGKAIERLRVAAYCRVSTDSEDQLNSY
                     KSQVQYYTDMIKKNKEWVLADIYADEAITGTQVTKREDFQRMINDCMNGEIDMVFTKS
                     ISRFARNTLDTLKYVRMLKERNIAVYFEDEKINTLTMDGELLLVVLSSVAQQEVENIS
                     ANVKKGLKMKMKRGELVGFQGCIGYDYHPEDKTITVNQEEAEIVRYIFNRYVDGAGGS
                     VIGQELESLGYKTKYGSSTWAPSTVIGIIKNEKYKGDILLGKTFTVDPISKRRLENMG
                     EEDKFYMKDHHEPIISEEVFEKAQEILNRRNKNRTTVGSGKREKYSRKYAFSCMLECG
                     FCGGTLTRRNWHSGSKYSKVIWQCVTATKKGKKFCKHSKGIPETAIEEAFVESYRLLC
                     DDNKDVLEEFLQRMDDTLSSSVVSKQLAKAEKEIDALEKKKSKLVDMRLEEIIDKETY
                     ESKYADLVSKQEQLVEERQKLQETSDNEKDIKKRLKEFKKTLEQNEVLDKFDRYVFES
                     IVEKVIVGGLDENGNVDPAQLTFVYKTGLKNSVDGAKFKTQRKNARGRHRTNELCSHD
                     SNEVDKMCSDSSNDTCGNCS"
     gene            complement(14229..14867)
                     /locus_tag="PC512_001608"
     CDS             complement(14229..14867)
                     /locus_tag="PC512_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441354.1"
                     /translation="MSNQRKDFDITNDMFQESIPITTKIILEDMPSNDELNHVFSKGC
                     ERKMKKRKIVLITLLLIGVLLLGSILYNLFLGKTANISMLKESWNFDIPIPNKEIEVF
                     DTQDSINGDGQSYFIQGFSEKNFKKVFNLKGGIVVSKDNINEIEKYIDKFKRDSVNIN
                     KSNKNKIEEDFKKYKLEVKKDDKYIYKRNYENYVVLIIKKDEQKLYSLIWNQ"
     gene            complement(15277..15453)
                     /locus_tag="PC512_001609"
     CDS             complement(15277..15453)
                     /locus_tag="PC512_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441355.1"
                     /translation="MFRDKMDRCTHMLTAYIGSSYDYCDFIDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     regulatory      complement(15507..15603)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            16400..16801
                     /locus_tag="PC512_001610"
     CDS             16400..16801
                     /locus_tag="PC512_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNHCP domain-containing protein"
                     /protein_id="HDF2441356.1"
                     /translation="MNYKNRKRAYYQENSCMDNFICKNCGCLVVPEGAGTQHRNHCPH
                     CLHSLHVDIIPGDRAADCDANMEPIGVWVRKNGEWAIIHRCTRCGHLSSNRIAADDNS
                     VKLMSIALKPLAQPPFPLERIIEKLEKEETE"
     gene            16798..17865
                     /gene="rsgA"
                     /locus_tag="PC512_001611"
     CDS             16798..17865
                     /gene="rsgA"
                     /locus_tag="PC512_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HDF2441357.1"
                     /translation="MNGMKQINLQDYGLNRNFITQSMEYHDLYLARIISQEKNFYQAV
                     CVNGVLFAEVSGKLRFEATIQSDFPTVGDFVMLDRCNNKNGNAIIHHVLHRKSLFVRK
                     AAGKVNEEQVVAANIDIVFLCMSLNKDFNIHRLERYLSLTWESGAIPVVVLTKSDLCD
                     NVHRKLQVVNSIALGVDVVVTSSIEPDGYKQISKYIKPGCTVALLGSSGVGKSSLINC
                     LMGGEFLNTKEIRIDDDKGRHATTRRELFLISGGGIVIDTPGMRELGMWDVSEGLDKS
                     FADIEAYFGKCHFRNCTHTSEPGCAIWEAIAHQELSPKRWESYRRLKTEAVFADNKSE
                     YLAKKEKKFKNISKINKKIRR"
     gene            18401..19099
                     /locus_tag="PC512_001612"
     CDS             18401..19099
                     /locus_tag="PC512_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441358.1"
                     /translation="MKISSQYRSQYSFRYESNINNTRINESMVKKNETVGKDTYLSNI
                     MKQKQELNDRIRDLKYRQEVYTKKINDAIKNLCKSEIRETTNNFSNIEIGIKNSIIEE
                     KNKSTMLDENSTYLNTNDEKESLITKESNEKIEEEILNDEKLEELEQKKDYKEDSNKK
                     EKVSEDLSLVGKTREELENMLKNFINLTQEEIMKLESRIEKLDKNAEEYKQNSKTNIF
                     DKTDEQKKHINVLI"
     gene            19277..20167
                     /locus_tag="PC512_001613"
     CDS             19277..20167
                     /locus_tag="PC512_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441359.1"
                     /translation="MKKNILTTMITMIIILMMSMTVMAEPYQEDETSSLKKQSANERN
                     QTNIGTMDGRVQTNAISKGANYDPKYPLKGMLTQLGLNTTGKEGWDLLYGGNPNGVEL
                     RADGKYYYINKGMEGLGFYAAALSGGSYQRIGFGKLDPIEVIADGNWISYKQAQDTLT
                     VIRNFLNSFDWRNASEMERANRAAKLVTEAKYADSKYCNIVYGNLVDKRGVCGSFASS
                     FHLLTRLMGMDSLSILNPSLNHAWNYIQIDGKWYRFDGSEISAFGGSLDFDYRKLKDA
                     TREMTTYYDAKALSILGFNQ"
     gene            complement(20560..21516)
                     /locus_tag="PC512_001614"
     CDS             complement(20560..21516)
                     /locus_tag="PC512_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDF2441360.1"
                     /translation="MENNTIQKQLRDLSKKIWHIYILNPEEENLKFIISLLDDNLALI
                     GTGKHEFYETLEEFIIGLEKDQTESEQIDFEIIDEWYSCTKVTDEAFIVYGTLWVIEK
                     DYLEKDIYVEMDTRFTMVYRVTDDMIKLIHVHHSIPNFDQMKDEYYPKTITEKAQEAL
                     AMANEFKLKSEKDLMTGLYNRHFFEVHIKEMLKTVSHGYFYIFDLDNFKQVNDIFGHV
                     RGDEILIHFSNILTKVFVNDAIIGRLGGDEFAVFEYSNQSKENVENKAKKVLELCLES
                     NSCSIGISKLENNSDTFQSLYKQSDYALYYSKRNNKGNFSWF"
     gene            22219..23214
                     /locus_tag="PC512_001615"
     CDS             22219..23214
                     /locus_tag="PC512_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2441361.1"
                     /translation="MSIIELNELTKSYRRFEKKAGFMGSVKSLFNRKYTEKTAISSFD
                     LKIEEGEFVGLIGQNGAGKTTLIKMLTGIIAPSSGEISVMGYYPNKLENNFKKQYAVV
                     MGQKSQLFFELTPADTFLLFKELYDISNEEYKKNLDYFIELFEVSDYLNVQVRTLSLG
                     ERMKMELIVALLHNPKILFLDEPTIGLDAIAQKQIRYFLKEVNETKGTTIILTSHYME
                     DIKSLCSRSIVVENSRKIYDGSTEKLFNYFQKYKKITVSFSNETNIVFPKDCKVVEQT
                     NHKISVIVPKERGNETIKWIFDKYDVKDVMIEEEDIGSIVERIYKKGSDEYYEQL"
     gene            23192..24055
                     /locus_tag="PC512_001616"
     CDS             23192..24055
                     /locus_tag="PC512_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HDF2441362.1"
                     /translation="MSIMSNYNEASSNDSMFYKFKQSIRRYYEVAKINFKVQLIWRFD
                     VVVNMVFTIVKILFAYILWKAIFGENKIVSGFTFNSMLSYYIISSFLAGIDMSKSTSE
                     EICNRVKLGTFSKYMIIPINVQNYFIAKNFGMTCFYFVFNMISAFVWIFIFKIDFAFT
                     SNPVQILISILMIFLGFIFMMKLHFFIGILSFKFLEISFLKMIIENIVEFITGTMIPL
                     VLLPETIVTVMKVFPFYYTTYLPSMLLIGRNSNEAIQGLIILALWVLFFSVVNKVMYK
                     RMRTLFDGVGI"
     gene            24052..24846
                     /locus_tag="PC512_001617"
     CDS             24052..24846
                     /locus_tag="PC512_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HDF2441363.1"
                     /translation="MMKKNLKIIFMLLKMKLSKMMVFRFDFFGAFFVDSSLFILQLLM
                     FNSIYSHVDSIGGWQQGEMLIFIGTFSLINAINMTIFFFGIYDIPRKIQEGELDYYIT
                     KPLDPLFRLTFENINIGSSPLILASILIVLYGISELNSEITLVMIIIYIFMVLLMTLL
                     FYDVCIILRTVSFFVISSSAIMRLEDNLLPMNMKIPGVIYEGIFKVLFYLILPYGIMS
                     TIPTQILAGTITINGLIYSILIVFLFTLFMWRFWKLGMRHYKSASS"
     gene            25131..26510
                     /locus_tag="PC512_001618"
     CDS             25131..26510
                     /locus_tag="PC512_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2441364.1"
                     /translation="MSDVYYSENHEQDNLYEQDNLLAQRFNLFTLLKFAFPTIFMMIF
                     MGLYTIVDTIFVSRFINTNALSAINIVCPIINLIVGIGTMLATGGSAIVARKMGNGDI
                     EGANKAFSLIVLSGVVIGVIITGIGIVFMDYIIIWLGASEVLIKYCRSYLFIILVFAS
                     ANILQVLFQCLFVTAGKPQFGLWLVLGAGCANIILDYVFIVLLQMGISGAALATGVGY
                     LIPTISGMVFFSKNKGLLKFCIPRLDKRILFEACFNGSSEMVGQLSTAVTTFLFNAMM
                     MKLIGEDGVAAITIIIYSQFLLTSLYIGFSMGVAPIISYNYGSENNTQLNHVFKICIL
                     FISVASLLVFIFSISCSPIIVEIFSQRGSRVYEIARSGFYIFSFSFIFCGYNIFTSSM
                     FTALSNGKVSAILSFLRTFGFITIGLLILPNILNINGIWLAVPSAEILTLFLTVFCIF
                     KYKNRYKYM"
     gene            26958..27671
                     /locus_tag="PC512_001619"
     CDS             26958..27671
                     /locus_tag="PC512_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2441365.1"
                     /translation="MDTCFNKKILLVDDEKDIVDLIEEVLINDGFKNIIKAYNGLDAI
                     SLCKIACPDVVILDIMLPDIDGIEVCKKIREFSYCSILFLSSKNDDIDKILGLSSGGD
                     DYITKPFSPREIAFRVKAQLRRQQYQSIVPSDSEVIKIGDITIDIEGNRVYKDRNEIE
                     LTGREYHLLSYMAQNVNKIIGKERLYEQVWGVYSSICDNTIMVHIRHIREKIEDNPSN
                     PKILITVKGLGYKLVNRID"
     gene            complement(27943..29481)
                     /locus_tag="PC512_001620"
     CDS             complement(27943..29481)
                     /locus_tag="PC512_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDF2441366.1"
                     /translation="MSLLKVTNLSQCFMDKSLYEKANFDLFKGEHIGVVGQNGTGKST
                     LIKILLGEVVPDSGEIKWQPNINIGHLDQYAEINRDTTISLYLHTAFEELYKIEKEMN
                     LLYQKSAISENEQYLIKASDYQEQLIASNFYSIDNEINKIANGLGLDSIGMNRVVREL
                     SGGQRAKVILAKLLLSNHDVLLLDEPTNFLDKEHVEWLSNYLNTFNGAFIVVSHDFDF
                     LEKISTGILDIEFGMIKKYHGKYSEFLKQKSHLREDYIRRYQAQQKKIEKEETFIRKN
                     KAGVNSKIARGRQKQLDKIERIAPPSFTGKPNIQFSEIEISAQNALTITNLEVGYYYS
                     LLPKLNFSVDGGQKIVITGFNGIGKSTLLKTLVKDIPRISGDFQFSEQVKIGYYEQDL
                     KWENPDKTPLQIVADKYPKLNTKEIRRHLARCGVKEEHVSRSVSTLSGGEQSKVKLCC
                     MMLSPCNFLILDEPTNHFDAETKDALQNALKQFRGSIILVSHEEKFYKGWIDKVFNIE
                     KQLV"
     gene            30363..30818
                     /locus_tag="PC512_001621"
     CDS             30363..30818
                     /locus_tag="PC512_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HDF2441367.1"
                     /translation="MDEIDLKIINSLKKNSRASTSEISRQINLSVPAVSERIRKIEQS
                     NLIQKYTIQINREKTKYKLLAFIFINTDLSKSMKEFKKTILEYDTVLECHHISGEYDY
                     LIKVLAEDTSNLEEFISVTLKEIGGIQKANTTIVLSTIKEEFNTIKDIF"
     gene            30867..31451
                     /locus_tag="PC512_001622"
     CDS             30867..31451
                     /locus_tag="PC512_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HDF2441368.1"
                     /translation="MKVLVFLAKGFETMEFSVFVDVMGWARNDYGHDIDVVTCGFKKQ
                     VMSTFNIQVLVDKTIEEVCVDDYDALAIPGGFEEFGFYDEAYDSSFLNLIREFNSKEK
                     IIASICVAALPVGKSGVLKNRKATTYHLKNGKRQRQLSEFDVNVVNEPIVVDKNIITS
                     YCPETAPHVAFKLLEMLTSKEQMDEVKLAMGFKL"
     gene            complement(31456..31779)
                     /locus_tag="PC512_001623"
     CDS             complement(31456..31779)
                     /locus_tag="PC512_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2441369.1"
                     /translation="MKKCLDNYSCPIEATLALIGGKYKTLILWHLKDTILRFNELKKL
                     IPKATPKMLTQQLRELESDGLIIRVVYPVVPPKVEYSLSDFGKSIIPILDSMCDWGSD
                     YLENL"
     gene            31931..32449
                     /locus_tag="PC512_001624"
     CDS             31931..32449
                     /locus_tag="PC512_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF2441370.1"
                     /translation="MNFVELAKKRYSCRNYQDRKVEKEKLEKVLDVARIAPTGGNRQP
                     QRLIVIQEKEGINKLSKAANIYDAPLAILVCGDKDKVWTRPFDGKQLTDIDTSIVTDH
                     MMLQATELGLASVWVCYFNPDIIREEFSLPDNLEPINILLMGYESKIPESPERHEKTR
                     VPLSEIVSYETL"
     gene            complement(32625..33293)
                     /locus_tag="PC512_001625"
     CDS             complement(32625..33293)
                     /locus_tag="PC512_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-binding protein"
                     /protein_id="HDF2441371.1"
                     /translation="MLEVSHKVKEIYPNIKFGVMVINITHSKPNKENFLVLKNSTIKN
                     IIEQHPEYNRKEKIKTEPVSSYIKYYKKFKKTYPVLLQLESILLKSKGIPDVGVTIES
                     MFLAELKNLLLTAGHDLDKMELPLKIELANGSEHFYGIGGKEHILTKDDLFLSDNIGI
                     LSSILNGPDNRTAITKDTKNIMYFVYGPDKISEKQIQDHLNDIKHYISSAFPDLKVNS
                     IDIF"
     gene            33408..34823
                     /locus_tag="PC512_001626"
     CDS             33408..34823
                     /locus_tag="PC512_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDF2441372.1"
                     /translation="MWITINRNSNISLSRQIYCEIKDMILDGSLKFEQKLPSSRTLSK
                     ELSVSRNTVLDAYNQLIAEGYLETRNGYGTIVAKGISGHKVDFKLNDTFRDEKDLHTN
                     KQKNYIDFRSGVPELKLFPRKELSKLYKQILYDLSDSDFRYGSTAGVWVLRVEISKYL
                     FRTRGIRCNPKNIMIVSGSTQGLSLISQLLYKSNKKVAVEDPIHKGLLKVISSIGYSV
                     VGIKVDDKGMNTNLIKSIKGISFVYTTPSHQYPLGGILPIQRRLELIKCATENDYYII
                     EDDYDSEFRYEGQPISSLYELSPNKVIYIGSFSKILSPAIRVGFMLLPDNILESYKTL
                     KMYSDVHTETILQHVLAEFIGNGGLEKYIFRMKKLYNRKRKYLIKVLNTEFKNEFKIK
                     GEAAGLHIVAHFYNVKFTESLIHKIFEAGIKVYPIQQYAIENILEYDYEIILGYAHLS
                     FDEIEKGVKILSKIIHMNQGT"
     gene            35046..35504
                     /locus_tag="PC512_001627"
     CDS             35046..35504
                     /locus_tag="PC512_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2441373.1"
                     /translation="MEIIDYIEENLTENLNLDKIAYIANYSKYHLHRMFTNVVGCTIH
                     QYIQRRRLTEAARQLIFTDKYIIDIAITVGYSTHQSFTLAFRNLYKESPQVYRNKDEF
                     YPIQQRFVLNLNHQIQSEKCISYANMNYKQRRDEINSYLNFNINCEVKVA"
     gene            35501..36085
                     /gene="clpP"
                     /locus_tag="PC512_001628"
     CDS             35501..36085
                     /gene="clpP"
                     /locus_tag="PC512_001628"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HDF2441374.1"
                     /translation="MSLVPHVIEQTGQGERSYDIYSKLLKDRIIFIGEEINDAIASLV
                     VAQLLFLESEDPDSDIIIYINSPGGSATSGFAIYDTMNYVRCDVSTICIGMAASMSAF
                     LLAGGTHGKRCALPNSEIMIHQPMGGAKGQATDVKIAVDNILKIKERLDKILSENTGK
                     SIEDIRRDTDRDNFMTALEAKEYGLIDYIMNRNE"
     gene            36397..37473
                     /locus_tag="PC512_001629"
     CDS             36397..37473
                     /locus_tag="PC512_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDF2441375.1"
                     /translation="MITISLCMIVKNEEEVIGRCLECVKDIVDEIIIVDTGSTDSTKE
                     IVSKYTDMVYDFEWIDDFSAARNFSFSKASKDYTMWLDADDIILEADREKLLKIKESL
                     DTSIDIVMAKYNVSFDENGNPTLSYYRERLFKRSSNHKWVDPIHEVVPLFGEVFYSDI
                     AISHKKLHRQDPLRNLRIFEKMISEGKTLEPRHQFYYSRELYYNARYKEAIEGFTKFL
                     DSSRGWIEDCISACRDLATCYYLINDEKSALYSLFRSFEFDEPRAEICCDIGKHMFDR
                     QKYKEAIFWYKVALTRDKNDTNGGFKSNDCYGYIPSIQLSVCYDRLGESDKAIYYHEK
                     TKEIKPNDSAVLHNENYFSKFKNS"
     gene            37540..39612
                     /gene="bclA3"
                     /locus_tag="PC512_001630"
     CDS             37540..39612
                     /gene="bclA3"
                     /locus_tag="PC512_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA3"
                     /protein_id="HDF2441376.1"
                     /translation="MLLIMSRNKYFGPFDDNDYNNGYDKYDDCNNGRDDYNSCDCHHC
                     CPPSCVGPTGPMGPRGRTGPTGPTGPTGPGVGATGPTGPTGPTGPTGNTGNTGATGLR
                     GPTGATGATGPTGATGAIGFGVTGPTGPTGATGATGADGVTGPTGPTGATGADGITGP
                     TGATGATGFGVTGPTGPTGATGVGVTGATGLIGPTGATGTPGATGPTGAIGATGIGIT
                     GPTGATGATGADGATGVTGPTGPTGATGADGVTGPTGATGATGIGITGPTGPTGATGI
                     GITGATGLIGPTGATGTPGATGPTGATGPTGVGVTGATGATGATGADGATGVTGPTGA
                     TGATGANGLVGPTGATGAAGTPGATGPTGATGPTGVGITGATGATGATGPTGADGATG
                     PTGATGNTGADGVAGPTGATGATGNTGADGATGPTGATGATGADGATGPTGATGATGV
                     AGATGATGPTGATGATGADGATGPTGATGATGADGATGPTGATGATGVTGATGPTGPT
                     GATGATGATGASAIIPFASGIPLSLTTIAGGLVGTPGFVGFGSSAPGLSIVGGVIDLT
                     NAAGTLTNFAFSMPRDGTITSISAYFSTTAALSLVGSTITITATLYQSTAPNNSFTAV
                     PGATVTLAPPLTGILSVGSISSGIVTGLNIAATAQTRFLLVFTATASGLSLVNTVAGY
                     ASAGIAIN"
     gene            39781..40542
                     /locus_tag="PC512_001631"
     CDS             39781..40542
                     /locus_tag="PC512_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase"
                     /protein_id="HDF2441377.1"
                     /translation="MKNKIEISMNNFVKNYHKSNNITTKWQELLFAYASAEDDMFQKL
                     KSVVGTSHAMPKDFLENGKTIITYFIPFDESVNNSNIGGFECSEIWARAYIETNMLIS
                     NLNDFLCEELEKIGANSYAIPGSYNFDSEKLVSDWSQRHVAFIAGLGTFGLNNMLITE
                     KGCCGRIGSIITSLELEPTKRPENEYCLYKHNNSCKKCVNKCVKEALKEDGFNRNKCY
                     EMCMINEKKYTYIGGCDICGKCIVGVPCSVINPSR"
     gene            40851..41129
                     /locus_tag="PC512_001632"
     CDS             40851..41129
                     /locus_tag="PC512_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441378.1"
                     /translation="MSYKKAIHILPEELLELIQEYVDGECIYIPRKSNNKKEWGSNTP
                     TREELSIRNMQIYEDYQVGYDLQYLSEKYYLSLKSIQRIVLQEKRKDI"
     gene            41422..41997
                     /locus_tag="PC512_001633"
     CDS             41422..41997
                     /locus_tag="PC512_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1062 domain-containing protein"
                     /protein_id="HDF2441379.1"
                     /translation="MKKITWEVEYISQLPVIRYCKKCGKKTEYICSGLFRVNAQHKYL
                     DIWLIYKCSNCDSTWNSTIYSRVNPKSLNPEILEQFHTNDYNLVKQYAMNMELLHRNG
                     AEVGIPEYKIVGQEININDLTQVHIISKYPCQLKVSTLLREKLGLSRKVFDEMLDCGI
                     IRSNSGVDLKKGKLNYEIMLDIGKEKQKSSN"
     gene            complement(42103..42936)
                     /locus_tag="PC512_001634"
     CDS             complement(42103..42936)
                     /locus_tag="PC512_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prenyltransferase"
                     /protein_id="HDF2441380.1"
                     /translation="MNVENQSLSDIEIILSHRYDNGADYWTTPDKRLIKGSPFSTLDS
                     VLYLLELGVNPDDTLLKECADLIFSTWREDGRFKLYPNGGIYPCHTANAANVLCHMGY
                     ASDIRMQKTFQHFLDTQYTDGGWRCNKFSFGRGPETEYSNPLPTLNILNAFRFSNYLN
                     KESKLDKAVDFLLDHWTIKKPIGPCHYGIGTLFMQVEYPFRNYNLFLYVYVLSFYNRA
                     KKDKRFLEALKILESKMIGNKIVVERVVPKLSKLSFCKKGESSEIATTHYYEILKNLE
                     K"
     gene            complement(43004..43633)
                     /locus_tag="PC512_001635"
     CDS             complement(43004..43633)
                     /locus_tag="PC512_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3786 domain-containing protein"
                     /protein_id="HDF2441381.1"
                     /translation="MDEKITKNNYNVPFDYVRKKLKELDPHTISNLSNIPFNNDLNRF
                     TLNFFDRQYIIDYPSGEVWNSNGSLCNNFELKILIVRYLINAKGIPRTNKYVTFKEIP
                     GGNVYYPNFLNRTLYRLSEVFTSQIDKYKLVMEKIGAEKVNMGDLAYRFTYMGNTSMV
                     FILWFGDDEFPPNSNILFDSNIVYYFNAEDLAVVPDTAINAILNKINQL"
BASE COUNT        15272 a         5944 c         7942 g        14540 t
ORIGIN      
        1 acccgatagg atatacagac ctaagtagta gttactggca acagcactta atcggtgcag
       61 gacgagtaaa acaatagaaa ggacttgaaa aatatgttta agaagaataa gaaacagaca
      121 gaaaatgtca aagaaaaaaa ggtacgtact gtcaaggtag gcacacataa gaaaaccgtg
      181 attgcattgt gggtggtgct tattgcaagc gtgagctttg gagtatataa gaattttacc
      241 gctattgacc agcacacgac ccatgaaaaa gaagtgattg agcttcgctt gcaggacacc
      301 aacgggatag aaaatttcgt gaagaatttt gcaaagtcct attacacatg gagtaacagc
      361 aaagaagcga ttgacgcaag gacgcaggca atcagcggtt atctgacaaa ggaattgcag
      421 gacttgaata tggataccat tagaacggat ataccgacca gctctgccat tacagatgtg
      481 attgtatgga gcattgaaca gtctggaacg gacacttttt ccgctaccta cgaagtagat
      541 cagcagataa aagaggggga acagacaaca gcggttaagg caacctatac cgtaaaagtt
      601 catgtggacg ctggcgggaa tatggtaatt attcagaacc ctacccttgc accagcaatc
      661 gagaaatcag actatgaacc aaagacacca gaagcagacg caagtgtaga cgcggatacc
      721 ataaatgacg ctactgcatt tctggaaact ttctttaagc tatacccaac agccacagaa
      781 aaggagcttg cttactatgt gtctggaaat gtgcttgagt ctatcggcag ggactacctc
      841 tattctgaat tggtaaaccc tatctttacg gttgatgggg acaatgtgaa agtcaaggtt
      901 gccgtgaaat tcattgataa tcagacaaag gcaacacagg tatcgcagtt tgaattagtg
      961 ctacataagg agagcaattg gaagattata ggataattat tgaaagcgtg catttcttta
     1021 ggaatttgca cgcttttgtt aagagcatta ttctttatat ttatgaaaga catcttaaac
     1081 aaagtattaa tggcttcgca aaactttttt cttaatatat ttggattaga aaaagcgcat
     1141 cttaattgta gacttactat acatatgaat tatgccagtc aacgtattta aaatttatgt
     1201 tgttttattt tgttgtaaat cgcaagaata gataagagta atcaatggtg aaggggaatt
     1261 attaaaaata ctattggttt cttctgtccc gttccaattt gcgcattgta ttttttcata
     1321 aattacagag tggtcaatta tgtagttcag atattccata caaactaatt gtattgtttt
     1381 tacactcggt ttccatactg ccacttttgt cattctatca ctcataatac aaatattatt
     1441 atgagcaact tttctaagta gttcatttaa atttgataca tggtcaaggt gaaaaccaag
     1501 aagaagtttg tcagcactca tatgtgtcaa ggggaaatgc ctatttatgt gcgagagcgc
     1561 tatgagaaaa tgcttgccgt atccatccgt gctccaaatt tagaaggaat ggttgaaaac
     1621 tttgataagg atttatctcg ccctaacgag acggatttga tcgagctgaa aaatgccata
     1681 tcaaagtaaa ttgcaagaaa aaagcaagaa tataaatata gcattttcag aacactgtgt
     1741 taaaatgtta ttacttatac ttataaagga ggggatgttt cgtgtcaaaa gcaacactat
     1801 ttgatagtcg tatcaaaaaa tacgcatact gtagaacatc agaaatttat cgagacattg
     1861 gctcatctcc ggatggttta tccattgagc aaatcggttc aatgcgggag aaatacggag
     1921 cgaacagctt caatgggcgg aaaaatgata cgacgatgca acggttgaga cgggcattta
     1981 ttaacccgtt tcatgtgatt ctttttgttc tgggcattgt ttctcttgtt acggatgttt
     2041 tcgtagcatc caattttgcg agaaatgcta ctaccgccat tatcatcttt tccatgatcg
     2101 taattagtgg cgtaattcgt ctgattcagg agctgcgagc aaagagcgct gctgctcagc
     2161 ttgatcgcct agttcatgaa agcgtcacag tgaggcgtga tggaaagtta atagagattc
     2221 ctggcgaaga attagtggta ggggatattg tactattctc tgcaggtgat cgtgttccgg
     2281 cggatatcag attgacgaag attacggatc tctttatctc tcaggctgcg attactggcg
     2341 agagcgccat cattgaaaag agctgccgaa aactcagtta cggagagcag gatacactga
     2401 ctcagcttga aaacctcgct tttatggcaa ccacagtcat cagtggaaaa ggggaaggca
     2461 ttgtactggc agtaggcaaa gataccctgt atggaggatt taccaaaccg gattctgatg
     2521 ataaaaattc ctttaaaaaa ggagccgatt ccatcgcctg ggtgatgata cgttttatgg
     2581 cgatattagt tcccattgta tttatattac tggggattac tgatggaaaa tggatggaat
     2641 cttttgcttt cgccctgtca gttgctgtag gtctgatgcc ggaaatgctt cctatggtta
     2701 ttacagcctg ccttgccaaa ggaagtcttg ctatgagcaa aaagcagacc attatcaagg
     2761 atattaatgc catgcagagc tttggtagca tggatgtgct ttgtatggat aaaacaggaa
     2821 cacttaccaa tgaaagcatc ctgctggaat attatatgga tatttttggg aatgaaaatg
     2881 cagaggttct tgatcttgct tatctgaata gctgctatca ttctggtgtc tgcaatacca
     2941 ttgataatgc cattcttgcc tgcaatacca tgccagggcg ggaagcccat tacgcaaatc
     3001 ttctgacaaa attccaaaaa gctgatgaaa ttccctttga ctatgctcgt aagtttgtca
     3061 gtacacttgt acaggatagc aatgggaata gtcagcttat tatgaaaggt gatattgaac
     3121 atatattctc acgctgcaac catgtagaat atcgtggaaa acttctcccc atggggcagg
     3181 atgcgagaca gagtgtatct tctgtagtag gtgaaatgtt acaggacgga atgaaggtca
     3241 ttgcggtggc acgaaaaaat gtgggagcgc aaaagaaaat aactcctgat gacgaatggg
     3301 gcatgactct agttggctat ctatccttct ttgatgcacc aaagcagaca gcaaaggagt
     3361 ctgtaactgc actcaaaaga ttaaaagtta tccctaagat tctgacaggg gaccaggcag
     3421 cgattgctgt gtctgtttgc cgccgggtgg gtatttatac agagcgtatc ttaactggta
     3481 ctcaactgga tgaaatgaca gactgtgaac ttaaaaaggc tgtggaacat actcatgttt
     3541 ttgcagagct tactccggga cataaggtgc gtcttgtctc tgctatgcag gataatggtc
     3601 attccgtggg atttcttggt gatggagtca acgacattcc ggcactgaat gaagcaaatg
     3661 tgggaatctc tgtagatacg gcagtggacg cagcaaaaga tgctgccgat gtggttttgc
     3721 tgcaaaagga cttgaatgtt ttggagcaag gtgtaatgga ggggcgaaaa acttttacca
     3781 atatgctgaa atatattaaa atcaccgcta gctctaactt tggaaatatt ttttccatca
     3841 tttgtgccag tgccttttta ccgttcctgc ctatgacttc aattcagatt ctgcttttga
     3901 atctgctgta tgatacgttg tgtattgtgc ttccttggga caatgtagat gaggaagaga
     3961 tgctgtcccc aagagactgg tccggcaaaa cactgagaca gtttatgctg tctttcggac
     4021 cgatcagttc tctgtttgat attgtcacct tcctattttt gtattatttc ctatgtccga
     4081 tgctatgtgg aggggcaacc tatctgcagc ttacagatcc ttccctgcaa cttcagtatg
     4141 tagcactgtt tcagactgga tggtttttgg aatctatgtg gacacaggtt ttgattttac
     4201 attttctgcg aacttccaag attccttttt tccagagcag ggcatctgca ccggtcattt
     4261 ctataactct agtggggatt attgctttta cttcccttac atttgtcggc ggtgcgtcgt
     4321 tgtttggact gacgaaatta cctctttggt atttcgtatt tttactgctg gtggtatctc
     4381 tctatatgct gctgaattca gtagccaaat atttttataa gaaaaaatat caagagttga
     4441 tttaagagga ggcattcatg atgaaaaaga atattagtta tattccgatg gattcggctc
     4501 ttgaaatctg gctattagaa aaactactaa gagatccacc ggacagtgat tgtgcgaagg
     4561 atttactttc tggtattcag gagatgattc gtggagaggt atcttcgtta ttgttaggag
     4621 catcagaaga aagcgattgg ccagtgggta ctctgtcaga tagaatcctg gcaggggatc
     4681 tggaaattta tccaagaggc agaaaagtac tgataaaagg ttctgaagtc aacctgactc
     4741 caaaggaatt tgatattttg tactttcttg tccagaacaa aggtgaagtt tttacaaagg
     4801 aacagattta tcgtgccgta tgggaggaag attatattct ggataacagc aacattatgg
     4861 cttttatccg gaagttgcga aaaaagattg aacctgctcc ggattgtccc acatatattt
     4921 tgaccatctg gggtattgga tacaaattta atgatcagat atgacaaaga cggactaaga
     4981 ccattttcgg tttcagtccg tctattttct taccaaatcg caagaaaatc gcaagacttt
     5041 agccatagga ttgtatttgg attttttata tactgttagt agttaaaggg aggtgtttca
     5101 tatgttttac acagatttta ttttgagaat tgccctctcc ttaacacttg gatttcttat
     5161 tggattagaa cggcaattga ctggtcatcc tgcaggtatt cgtatcaatg tgttaatctg
     5221 catgggtaca agtttcttta ccttgtttcc tatgctctac ggttcggatc aggtattccg
     5281 tgtcggaagc agtattatat ccggtgttgg ttttttatgc agtggtgtta ttttcaagga
     5341 cagagggaca gtacgtggaa tgaataccgc tgccacctta tggtgtactg cagcgattgg
     5401 aattcttgca agtacgggaa tgtatgcaat ggcgatcacc gccgctacta ttttaattgg
     5461 ttccaacctg attctacgtc cctttgcaag aaagtttcac ccaattactt ccagtgatga
     5521 atctgaaaag cagtatcgta tttcggttac atgtcaggaa aaggcagagc aggatatacg
     5581 cttattgctg attaacagca attcctgtaa gacgctcttt ttgaacaatc tggaaagcgg
     5641 tgatgtggtt ggtgacaagg ttgagattgt cgcagaatac tgttctgtcg gaaaatccaa
     5701 aaacaatatt ttagaaggaa tcgttgggca ggtattggta attccggaag tgattagtgc
     5761 tggttgggag gtgttgtgag tgaggagaga aatcgaagat ttgaaacgag caattctttt
     5821 tgctttctac cctgtattta caatcttatg tagctatttg ggttggaatt tctttgaaca
     5881 aagaatggta atctttaaga tatggtatca ggtgagtatt gtgatctggt ttattcttgc
     5941 tgttactatt attgtgctct tcattaaact tctgaagctg acaaaactaa gaaacaggtt
     6001 taagcattga aaggaggaac aaacgatgga ttttacatgt atcttttttg gaattttatt
     6061 tactcttgca ggcttttggt tggcctttgg aaaaggatat cgtcatcttt ccctgtggaa
     6121 aaatatgccg caggaggaga aagataaaat taatattgtc ccgctttgtc gtaatgttgg
     6181 agaaatgatt gcgttaaatg ggattatatt cttaatgaaa ggatttttgc cgggattttc
     6241 aaaccactgg tttgtatttg caataatcgc atggctgatt gttgccggct ttgatgtctg
     6301 gtatatcgaa aaaagtgtcc gctatcgcaa ccaataatcc acattgaggt ttcacataga
     6361 tattttttta agattgtgag gtgaaagaca tggactctga tgtcagtcca cgaaggcaga
     6421 gaatattata tgagaatttg gagattccgt gtcgctcata taatattcct tgcccctatg
     6481 aaaattcaag gaggtaagac caatgaacaa aaaagaaaat cgtatggcta ttcgtcagac
     6541 tgtagaaaaa gcagtcatcc gtgacgaaca gaaccgccgc attcaatttg cggcaaccaa
     6601 tcctattaaa gaagttttaa aaaaacttca taccacactt cgtggcttag aagtagatga
     6661 agtatccgta agtcgtgcta aatatggtac caataaagtc actcatgaaa aaaagaaatc
     6721 tctggcaaaa cgactggttg gcgcatttat caatccattt accgccattt tattttgtct
     6781 ggctttagta tccacaatta cagatatgat ttttccgtat ttttctctgt ttggcagtgt
     6841 gccagaggac tttgattccc tgactgttgt aatcatttta acaatggtat tcatttccgg
     6901 tacgcttcgt tttgtacagg aatccagaag cggaaatgca gcagagaaat tgttagccat
     6961 gattacgacc acttgtacag ttactcgtag aaactatgaa aaaaaagaac ttcctatgga
     7021 tgatttggtg gtgggagata ttgtgcatct ttctgctgga gatatgattc cggcggatgt
     7081 tcgtattttg gatgcgaagg atttgtttgt cagtcaggca agtcttactg gtgagagtga
     7141 acctattgaa aaaacaccca atgtaagtgc tcagaaagaa agcgtgactg attacacaaa
     7201 cattgctttt atggggagta atgtaatttc tggtagcgca acagctgttg ttgtttgtgt
     7261 tggcgatcat actctgtttg gctctatggc gtccgcagtt gctggagaag cggttgaaac
     7321 aagctttacc aagggtgtca atgccgtttc ttgggtattg attcgtttta tgctcattat
     7381 ggttccgctg gtgttctttg tcaatggtat caccaagggc gattggttgg cggccttctt
     7441 attcggcgtt tctattgctg ttggtttgac accagaaatg ttgccgatga ttgtaacaac
     7501 ctgtcttgcg aaaggcgctg tttccatgag caagaagcag acaatcgtta aaaacctcaa
     7561 ttccattcag aacttcggtg ctattgatat tctctgtact gacaagactg gcacgctgac
     7621 ccaggataag gttgtgctgg aataccatct gaatgtaaat ggcgaggacg atacgcgagt
     7681 actgcgtcac gcttacctca atagttactt ccagactggc tataaaaacc tgatggattt
     7741 ggcaattatc cataagacgg aggaagagga agccgcagat tcgcgtctca ttgacctgtc
     7801 tgaaaactat gtgaaagtag atgagattcc ttttgacttc acacgtcgtc gtctgactac
     7861 agtggtacag gataataagg gtaagaccca gatggtaaca aaaggtgctg tggaagaaat
     7921 gctctctatt tgtgcgtttg cagagtgtaa tggaggagtg cagcctctga ctgatgacgt
     7981 tcgttacaga attctggaga cagtggacaa tcttaacgat aagggattcc gcgtactagc
     8041 tattgcacag aagagtaatc cttccccaat cggcgcattt ggtgttaaag atgagtgtga
     8101 tatggtactg attggatatc tggcattcct tgatcctcca aaagaatcta ctgcggatgc
     8161 tattaaagct ctgaaagacc atggtgttat aaccaaaatt ttgacaggtg acaacgacaa
     8221 agtgactcga actatctgca agcaggtggg attagaggtt cgcaatatgc ttctcggttc
     8281 tgatttggaa caaatgggcg atgcagagct tgcaagagtg gcagagtcta cagatgtatt
     8341 tgcaaagcta acccctgatc agaaagcccg tgtggtttct gttctccgtg aaaatggtca
     8401 tacggtcggt ttcatgggtg acggtattaa tgatgctgca gctatgaaag ccgccgatat
     8461 tggtatttcg gtggataccg ccgtggacgt ggcaaaagaa tctgctgaca ttattctatt
     8521 ggaaaaagat ctgatggttt tggaacaggg tattattgag ggacgaaaga catatgccaa
     8581 catgatcaag tacattaaaa tgactgcttc atccaacttc ggcaatatgt tctcagtgct
     8641 tgctgcatct gctttgctac ctttcttacc aatgatgagt gttcatctta tatttctaaa
     8701 cttaatttat gatttatcct gtactgcaat tccttgggat aatgtggatg aggagtttat
     8761 taccaaacct cgtaaatggg acgcttccag tgttggaagt tttatgatct ggattggacc
     8821 aaccagttct atctttgatt ttacaaccta tatttttatg tactttgtat tttgtccatt
     8881 gttcgtatcg aatggtgtat tatttaatga tttgcctgct catttcagcg gtgcagaact
     8941 ggcaatgctt caggcacagt atatcgggat gttccaagca gggtggttcg tggaatctat
     9001 gtggagccag acattagtca ttcacatgat tcgtactcca aagctacctt ttgttcagag
     9061 tcgtgcatca gctccggtga ctttgctaac aatgactgga attatagttc tgaccattat
     9121 tccgtttact gtgtttggaa ctatgcttgg atttgttgca ttgcctgcag catactttgc
     9181 ttatctgatt ccatgtattc tgctgtatat gactttggca acaagtttaa aaaaagccta
     9241 tgtccgtcat ttcggagaac tgctttaagg aggtggaatg atgaactgga aagaactttg
     9301 gatgaccctt tttggaacta ccgaatggct tggtcttaat atcggctttt gggtggctat
     9361 ggcagttgtg ttgctgattg ttattgtaat gaatgtagta ttttggtcca tgaaaccaaa
     9421 aaaagacaca aaagagtctt ataaataaga tatcagtatg aatgaatcaa gggagatgca
     9481 cagtttttta ttgtggaatc tccctatcat atcaaggcgc attcaattgt ggcaatttag
     9541 tagtaaagta tgtgtttttt tatcattgaa ttacctataa atgctgtata taagtggata
     9601 attgtaattt cgatataaaa attatggtac ttaaaagaaa tttcgttttt tattgtttgt
     9661 ttacgcgtct ataacgaaat cgtgaaataa tattcaaagg tagattttat tatggaatgt
     9721 atgtctgtag aagaagcttc gataaaatga ggagatatct gaaagaagga taaaaaaatt
     9781 atgtaatgga aacagaatcc caaatctatt gtaacaacaa tgacaggtaa tgaatggtta
     9841 cgtagattga taattcctat tcaaattatt atctatctta tattgagtgg tgttttgtaa
     9901 ttacattttt atacaaaaag aatatgttga acgcacaatg ataaatattt tgtattcccc
     9961 aactaataga ataaagtttt tgcttggaaa gtatgttata taggcattat ggtttgtaat
    10021 gatcacgttg acagattata ccgctatata tgaagtcaaa gaacttaaat catttacaag
    10081 tgagataatc tatctaagtc taaaaaactg gatttctcaa tctattgtca atgagtccat
    10141 tacttattat ttgtgttttg caaagaaatg ttttctactc tagtttactt tttagttact
    10201 aaatatcggg aattggtttt gttggactat attgatctga aagtatacaa aatattattc
    10261 cgtggtctgc tgtaacccct ataagtttat tagatgcaca aggattgcta ccttatattt
    10321 caattctact ttgttatttt gcaagactga ttataaatac atactgcttt agagggttta
    10381 gtttagttct ttttgaactt ttgaataaga cgacggttat atagccgccg ttttattttt
    10441 gcctaacgtt ggacaaatta ctggatggtc ttgttttatc ggctctaggg gtagccgtat
    10501 gaaacactta catattcaac aactttcgac catcggtagt tcattaaaaa aacatttaaa
    10561 ttctacggaa cataatgctc ctatatgtgg ttttttacag catataacag gaataatttg
    10621 tttagcacaa gatcagtacg tctgtattgc ccttgtgctt ttttactgca taaaactttt
    10681 tcaaaaaatt tttgcggttg ggtatcaaat cccacctttc atggtgagtg ttagtgcgaa
    10741 aagaggtaga agtcttttcg ctttagcaac tttcgctgga aagggggtga gattatgaaa
    10801 ccatcttctt tcgagggcgc tatcagactt caatttgatt gtctagctcg caaggttgta
    10861 ggacgaactg taaagaacta tgaccgagag cttggcagac gtgcaagacg tgaaacgccg
    10921 ttctgtgatt tatctgaaat ggagttaaac cagatcggtg ccatggacga atattgcgtt
    10981 gagtttacgt catttgatgt atttggttca gaagtccata tctatgatga acgcttatgt
    11041 gaagctatca aagaattaac agaaagccga cgtaacattc tgcttatgtc ctactttctt
    11101 gaaatgaccg acgctgaaat tgcagaggtt atggaaatgg aacgattttc cgtatgtaga
    11161 aacaggctgc acacattaaa gcttattaag gatatgtacg aggaggaata aaaacatgat
    11221 gaagtctaca aaaaagtgtc catcattctc gaccatcagt tctgcagctg acggtaacga
    11281 ggtggcaatt gaaaagattt tgaaccatta tgacgcttac atatcaaaag ccagcctacg
    11341 cccgttctat gacgaacacg ggaatatgta tatcgtgctt gatatggaac tgaaaggcag
    11401 gatacgggca gcgttgatta aagtaatctt agggtttgaa gtcaaagtga agtaaatata
    11461 acagagagta tctaccacct cattttaact cttttccgtt ctttgacaag tgaatacagt
    11521 aatcagatac gtttgatata cgacgagcca gcggactgga acgccacgac cactgaaatg
    11581 gggaaagcag cgagcgatta tgccagtgaa ccgcaagcga tctttggaaa ggttgctgcc
    11641 atgactcgta tatctgaata atgatacacc cgtatgacac ggttcaccca tcagaatggg
    11701 aatggtgaaa gtccagtgga gctgccgaag ccgtctgatt acttccataa ataaaaaagc
    11761 aaggagggtt ttaatgaata atataattag gtatagtatg caaattgcta tgttaaaaca
    11821 actgcttgcc cgtaaactga tttctgaaaa agaatacact cttgtaaaac aaaggctgat
    11881 gaaagactat aaggtgcttt ctgacataac tgcttgaatt gtgtttttta aagtagtaca
    11941 ataacaatat gaaaggaaca caaaataagg aggtgtacta tgcaggaagt tgaagtaata
    12001 aaagcaaaaa atgttttggc aagacaagcc cgtggaaaag ccattgagcg tttgcgtgta
    12061 gctgcatatt gccgtgtaag tacagatagc gaagatcagt taaacagtta taaatcacaa
    12121 gttcagtatt atactgacat gattaagaaa aacaaggaat gggtgttagc tgacatttat
    12181 gctgatgaag caattacggg gacacaagta acaaaacgag aagattttca gcgtatgata
    12241 aatgactgta tgaatggtga aattgacatg gtatttacaa aatccatatc aagatttgcc
    12301 agaaatactt tagacacatt gaaatatgtt cgtatgctaa aagagagaaa tatcgccgtt
    12361 tattttgaag atgaaaaaat caatacactt acaatggatg gagagttatt gcttgttgtt
    12421 cttagttctg ttgcacagca ggaagtcgag aacatttcag ccaatgtaaa aaaagggttg
    12481 aaaatgaaaa tgaagcgcgg cgagctggta ggttttcaag gttgtattgg atatgattat
    12541 cacccagagg ataagacaat aactgtaaat caagaagaag cagagattgt cagatatatt
    12601 ttcaaccgtt atgttgatgg tgctggtggt tctgttattg gacaggagct tgaaagtcta
    12661 ggttataaaa cgaagtatgg gagttccaca tgggcaccat ctacggttat tggaattatt
    12721 aagaatgaga aatacaaggg tgatatactc ttaggcaaaa cttttactgt tgatccgatt
    12781 tccaaacgtc gccttgaaaa catgggtgaa gaagataaat tttatatgaa agatcaccat
    12841 gagccgatta ttagtgaaga agtttttgaa aaagcacagg aaattcttaa tcggagaaat
    12901 aagaaccgaa caacggtagg cagcggtaag cgtgagaagt atagcaggaa atacgcattt
    12961 agctgtatgc tagaatgtgg cttttgtggt ggtactttaa caagacgtaa ttggcacagt
    13021 ggctcaaaat acagcaaggt tatatggcaa tgtgtaacgg ctacgaagaa aggaaagaaa
    13081 ttttgtaaac atagcaaagg tattccagaa acagctattg aagaagcatt tgtagaaagt
    13141 tatcgtttat tatgtgatga taataaagat gttctggaag aatttttgca gagaatggac
    13201 gatactctta gtagtagtgt ggtgtcaaaa caacttgcaa aagcggaaaa ggagatagac
    13261 gcattagaga agaaaaaaag taaacttgtg gatatgcgtc tggaagaaat tattgataag
    13321 gaaacctacg aaagtaaata tgctgattta gtaagtaaac aagaacagct tgttgaagaa
    13381 agacaaaagt tacaagaaac ttctgataat gagaaagaca taaaaaaacg tttgaaagag
    13441 tttaagaaaa ctctggaaca gaatgaggtt cttgataaat ttgaccgcta tgtgtttgaa
    13501 agcattgttg aaaaagtaat tgtaggtgga cttgatgaaa acggaaatgt tgaccctgca
    13561 cagttgacct ttgtttataa aacaggcttg aagaatagcg tagatggtgc taaatttaaa
    13621 acacaaagga aaaatgcaag aggacggcat aggactaatg aattgtgttc acatgacagc
    13681 aacgaggttg ataaaatgtg ttccgatagt agtaacgaca catgtggaaa ctgtagctaa
    13741 gataatcaaa caatagtaat gtttatatag attatatact aataatatat tgtatttgcc
    13801 accgatttgc cactgtaaag cgatttcggt ggcaaattta gtctacaatg ttatcaaaaa
    13861 tctctaaagt tttattttta attctataaa acttattata attgtaattt taaaagaaat
    13921 agtcaatcta cagtagccag attttataca actcattttt ttcatagagt aatttacata
    13981 atctatagtt gaatattatt taatattttt ataattcatt agcaaatata ggcattacaa
    14041 atgttgataa acatgtgaaa gcacatatcc acttataatt atttttttta aaaccataaa
    14101 atcacctctt catttgttgt atgtttttat aacaaatgaa gaggtgattt ccagacaatt
    14161 taaaaggttt ttgtatattg actaaaattt atttttatta tttataattc ttaataatac
    14221 atatgtacct actgattcca tattaaactg tataattttt gttcatcttt ttttataatt
    14281 aaaactacgt agttctcata atttctctta tatatatact tatcatcttt tttaacttct
    14341 aacttatatt ttttaaaatc ttcttcaatt ttatttttat tacttttatt aatgttaaca
    14401 gaatctcttt taaatttatc aatatatttt tctatttcat taatattatc tttgcttaca
    14461 actataccac cttttaaatt aaaaactttt ttgaaatttt tttcagaaaa tccttgaata
    14521 aaataacttt gtccatctcc attaatacta tcttgagtat caaatacttc aatttctttg
    14581 ttaggtattg gtatatcaaa attccaagat tcctttagca ttgaaatatt agctgttttt
    14641 cctaaaaaaa gattatatag gatacttcct aataacaaaa cacctattaa tagtagtgtg
    14701 attaatacaa tttttctctt tttcattttt cgttcacaac cttttgaaaa aacatgattt
    14761 aattcatcat ttgaaggcat gtcttcaaga ataatttttg ttgtgatagg aatgctttct
    14821 tgaaacatat catttgtaat atcaaaatct tttctttgat tactcaatat ccatttcttc
    14881 taatatttct tttgattttt tctagtacat tgaatactct tatatacatt ctcctctttt
    14941 aaaattaaaa gttataaaag aataagttat ataaaaaatt attatatttt ttaatatagc
    15001 ttatttgcaa atttataatt ttgttaatct aatccttcaa actaaaaaat catttatatt
    15061 tacagaattt cattttaaga gatgtttatt ttcacataga taagagaatt taagttctca
    15121 tatttattat ttgatacaaa tttacatctt tattatatgt attttaaata aaaaataaaa
    15181 ttatgaatac tagaaatcta tcttaattag ctttctaaca taaggctatt taaagtagat
    15241 aaaactaaaa agggttctct agaaaaccaa atctatttaa ttatacttac ttactaatac
    15301 catcacttga tgcaaacaag attctaccac attttctccg tactctagta taaaatcatc
    15361 tagttgtgta tctataaaat cacaataatc atatgaacta ccaatataag cagtcaacat
    15421 atgtgtacat ctatccattt tatctctaaa catatatatt attatccccc taaaaaactt
    15481 tcataaaaac aaaaagaata tctctttttg gcaactggct gacataactc atagtttatt
    15541 ttataagcgt tagtccctat agctttgcgt cactaaattt ctctagtttt gccgatttag
    15601 ttttattcta caattacaat aatacaatag aattgcttat tattcaatat acttatttga
    15661 aaattaaata aatttacaaa tatgaacgtt attttatatc aaaaaaaata gactatgcat
    15721 gtagaatata tggaaaaact tgattgtagg ttttgtatga aaagacagtt gttattaatt
    15781 taagtgagat aaattgagca acaggcataa aatgagaaaa caaataatag cagttaattt
    15841 ttattattaa tactaggtga acattaaatt tcaaaatacc actagatttt atagaataag
    15901 aaaatgagac aaacataaat atatgaatat attaaattat acttgaacat acttatattt
    15961 tatgataaaa tttcaataat aattattagt gaaggagtgt cttgcctgat gtcagagtta
    16021 tatataatgg taaccaacaa ataaatagtt ggagacgcat atgggttctg tttaatcaga
    16081 atttttaagt gtatttttga tacatttgat tgttgtgtct tactctgcct ttatagataa
    16141 ctaacattag acaacaaata ataatattac atattacttt gttaaattgt ggtgtagtgg
    16201 gctttaatct gctacacttt tattaatttt acacagtatt attttgaata taattatgtt
    16261 gaaatagaag atactaaatt ttctagtcca caggggtttt ctgtttttgt gtaggtaaat
    16321 atgtatacca cataaaaagg cagatataaa tacctgtgga ctttttttgt agaaaataca
    16381 cgatacggag gaaataaaaa tgaattataa aaatagaaaa cgagcttatt atcaggaaaa
    16441 ttcctgtatg gataacttta tttgcaaaaa ttgtggttgc cttgtagttc ctgaaggagc
    16501 tggtacacaa catagaaatc attgtccaca ttgtttacat agtcttcatg tagatatcat
    16561 tcctggtgac cgtgctgcag attgtgatgc taatatggaa cctattggag tgtgggtgag
    16621 aaaaaatggt gagtgggcaa ttattcatcg ttgtacacgc tgtggacatc ttagttctaa
    16681 tcgtattgca gctgatgata attcagtgaa attaatgtca attgcattaa aaccactggc
    16741 acagccccct ttcccactag aaagaatcat tgaaaagttg gaaaaggagg aaacagaatg
    16801 aatggtatga aacaaatcaa tttacaagac tatggtctaa atagaaattt tattactcaa
    16861 agtatggaat atcatgattt ataccttgct cggattatct cgcaggaaaa gaacttttat
    16921 caagctgtat gtgtaaatgg tgtactgttt gcagaggttt caggaaagct gcgttttgag
    16981 gctactatac aatctgattt tcccacagtt ggtgatttcg ttatgttgga tcgttgcaat
    17041 aataaaaatg gtaatgctat tattcatcat gtgcttcata gaaaaagctt gtttgtgcgt
    17101 aaggctgctg gaaaggtaaa tgaggagcag gtggttgcag ctaatattga cattgttttt
    17161 ttgtgcatgt cactgaataa ggattttaac attcatagat tggagaggta tctgtcttta
    17221 acatgggaaa gtggagctat cccagtagta gtacttacta aatcagactt atgtgacaat
    17281 gtgcatcgta aattacaagt agttaattct atagccttgg gtgtagatgt agttgttacc
    17341 tcatctatag agccagatgg ttataaacag atttctaagt atattaaacc aggctgtact
    17401 gttgccttac ttggttcttc aggagttgga aaatcttcat taattaattg tctgatgggt
    17461 ggagaatttt taaatacaaa ggaaattcgc atagatgatg ataaaggaag acatgccacg
    17521 actagacgag agctattttt aatttcaggt ggtggtattg ttattgacac accaggtatg
    17581 agagagttgg gaatgtggga tgtttcagaa ggtttagata aaagttttgc agatatagaa
    17641 gcttatttcg gaaaatgtca ttttcgtaat tgtactcaca cctcagaacc aggctgtgct
    17701 atctgggaag ctattgctca tcaagaactt tcgcctaaaa gatgggaatc ctatcgtagg
    17761 cttaaaactg aagcagtatt tgcagacaat aaaagcgaat acttagcaaa aaaagaaaag
    17821 aaatttaaaa atatctcaaa aataaataag aagattagaa gataagtgta gtttttttgt
    17881 tcattctatg agtctatata ctattaatat attaaatttg ccatcaattt gttactttaa
    17941 tgtgattttg atggcaaatt tggtttgtgg tattatttaa agcaatttat taattttttt
    18001 aataaagttt gattttttat atgatgatat atacatgtga taatgtatac atatttgtta
    18061 cgataggctc ctttataaag aggtcttatg taagataaga aaaggcatat ttatactaat
    18121 acataataga gtatatgctt atgtatgata gagatgtttc ttaagagcaa aactgcaata
    18181 ttgctaattt ataaagtaaa aatatatgaa ttataaaata caaataatat atttataaaa
    18241 attattgttt taatttataa taaaaatttt ttgttgaaaa taatgctcga acctataaaa
    18301 ctattaacta atatttgtaa atgtatactt ttgatgataa aatataatta agttaagttg
    18361 gtttttataa acataaattt attttaagga ggtgaaataa atgaaaatat ctagtcaata
    18421 tagaagtcaa tattcattta gatatgaaag taatataaat aatacaagaa taaatgaaag
    18481 tatggttaag aaaaatgaaa ctgtaggaaa agacacttat ttatctaata ttatgaaaca
    18541 aaagcaagaa cttaatgata gaattagaga tttaaaatat agacaagagg tttatactaa
    18601 aaaaataaat gacgcaatta agaacttatg taaatcagaa ataagagaaa caactaataa
    18661 tttttctaat atagaaatag gtattaaaaa tagcattata gaagagaaaa ataaaagtac
    18721 aatgttagat gaaaattcaa cttatctaaa tacaaatgat gaaaaagaat ctttaatcac
    18781 taaagagtct aatgaaaaaa ttgaagaaga aatattaaat gatgaaaaat tagaagagtt
    18841 agaacaaaaa aaggattata aagaggattc taataaaaaa gagaaagtat ctgaggactt
    18901 atctttagta ggtaaaactc gtgaagagct tgaaaatatg cttaaaaatt ttataaattt
    18961 aacacaagaa gaaataatga aacttgagtc gagaatagaa aagttagata aaaatgctga
    19021 agaatacaaa caaaattcaa agactaatat atttgataaa acagatgaac aaaaaaaaca
    19081 tataaatgta ctgatttaaa caatatgttt taaaaaaata agtttattat ataatgaaaa
    19141 tataaaggta caatttcaat acacttctat taaaccaata atttatgaat cagatttaat
    19201 ttcaatttac taataaccat atatttatga gttaataatt ttatgtttta aaaagaatta
    19261 aataaggggg agtagtatga agaagaatat attaactact atgattacca tgattattat
    19321 attgatgatg agtatgacag taatggcaga gccatatcaa gaagatgaaa catctagctt
    19381 gaaaaaacag agtgcaaatg aacgtaatca gactaatata ggcacaatgg atggcagagt
    19441 gcaaacaaat gcaataagta aaggtgctaa ttatgaccct aaatatcctc ttaaaggaat
    19501 gttaacacaa cttggtctta atacaacagg taaagaggga tgggatttac tctatggagg
    19561 aaatcccaat ggagttgagc ttcgagcaga tggtaaatat tattatataa ataagggtat
    19621 ggaagggcta ggattttatg cggcagcatt gtcaggtggc tcatatcaga gaataggctt
    19681 tggaaaactt gaccctatag aagtaatagc tgatggaaat tggatttctt acaaacaagc
    19741 tcaagataca cttacagtaa tcaggaattt tttaaatagc tttgactgga gaaatgcatc
    19801 tgagatggaa agagctaata gagctgcaaa attggtaacc gaagcaaaat atgcagactc
    19861 taaatattgt aacatagtct atggtaatct ggttgataaa cgtggtgtat gtggaagttt
    19921 tgcaagtagc tttcatttat taacaaggtt aatgggaatg gattcactat ctatattaaa
    19981 tccatcatta aatcatgctt ggaactatat acaaattgat gggaaatggt ataggtttga
    20041 tgggtctgaa atatcagctt ttggtggatc attagacttt gattaccgta aattaaagga
    20101 tgcaacaaga gagatgacta cttactatga tgctaaggca ttgtctatat taggatttaa
    20161 tcaataaaaa tagggggagg cttcttatag agcctttttt tattgatttg aaatttaata
    20221 aggaatttta tatgaaaatt taatcaataa aagcaaaaaa ggctctttat aaagcctttc
    20281 taagtgtttt tttaagtaaa attttttata tcaacatcag ttttaatcaa aacatataac
    20341 attttggact tacttttaaa aataaaatta ttaaaatata atattaatca tgtttttagt
    20401 ttattatatt ctataatagt ggtcatgttg actattgtag ttttattaag aatagttggt
    20461 ttatataaat atatgcaaag atagcttgtt gtttacttta cttattagta tataggacaa
    20521 gatactctaa taaatttgcc tattttaata tcttttgtac taaaaccaac taaagtttcc
    20581 tttattattt cgttttgaat aatacaaagc ataatccgat tgtttgtata aagactggaa
    20641 agtatcagag ttattttcta atttagatat acctatagaa caagaattac tctctaggca
    20701 taattctaaa accttctttg ccttattttc aacattctct tttgattgat tactatattc
    20761 aaaaacagca aattcatctc caccaagtct tccaataata gcatcattta cgaatacttt
    20821 agtcaaaata tttgaaaaat gtattagtat ttcatctcct cgaacatgac caaagatatc
    20881 atttacctgt ttaaaattat ctaaatcaaa gatgtaaaag tatccatgtg aaacagtttt
    20941 aagcatttct tttatgtgta cttcaaaaaa atgtctattg tatagtccag tcataaggtc
    21001 tttttctgat tttagtttaa attcatttgc cattgctagt gcttcttgtg ctttttcagt
    21061 tattgtttta gggtaatact catctttcat ttggtcaaag tttggaatag aatggtgaac
    21121 atggataagt ttaatcatat catctgtaac tctgtatacc atagtaaatc gagtatccat
    21181 ttctacatag atatcttttt ctaggtaatc tttttctatt acccaaagag taccatatac
    21241 tataaaagct tcgtctgtaa ctttggtaca tgaataccac tcatctataa tctcaaagtc
    21301 tatttgctct gattctgttt ggtctttttc aagacctata ataaattctt ctaatgtttc
    21361 gtaaaattca tgttttcctg ttccaattaa tgcaaggttg tcatctaata aggaaataat
    21421 aaatttaagg ttttcttctt ctggatttaa aatataaata tgccaaattt tttttgataa
    21481 atctcttaat tgtttttgta ttgtattatt ttccatagat taccccctta agatttacag
    21541 tttatatttt aatgtattat aagttgaact cttattacaa tattattata atatagaact
    21601 aaagaaatta catcctgtat aagtaaaagt atatctttta taataaaaat attacagtaa
    21661 aataaccagt tttaatatac gtattatatt tttaatttat aaacgaatat tataaatgaa
    21721 atttaaattc aaccctgaag aaataagcta aatgtattag tatataaatc catacttgaa
    21781 cataaataac ctttatgata tgatatcaat aataatatta tgagaggagt gccttgatgt
    21841 cggagttata taatggtaac caacaattaa atagttggag acacatatat tctgtataat
    21901 cagaaatttc aagtgtattt ttaatacatt taatttttgt gtcttattct gcctttatag
    21961 ataactgaca tatgacaaca aatagtattt aaaatatata ttactttgtt aaattatggt
    22021 gtagtaggct ttaatctgct acacttttat taattttgta tagtattatt ttgataacta
    22081 ttttgaaata gagagcatta atttttctag tccacaggag ttttctgttt ttgtgctgtt
    22141 aaatataagc acagagaaag gcagatatat acctgtggac tttttttata taaattatga
    22201 aatatggagg tagttaaaat gagtataatt gaacttaatg aactgactaa atcttataga
    22261 agatttgaga aaaaggcagg atttatgggg agtgtaaagt ctttatttaa taggaaatat
    22321 acagaaaaaa cagctatatc gtcatttgat ttaaagatag aagaaggaga atttgttgga
    22381 ttaataggtc aaaatggagc tggcaaaact actcttatta agatgttaac tggtattatt
    22441 gcaccgtctt ctggagaaat atctgtaatg ggttattacc ctaacaaatt agaaaataat
    22501 tttaaaaaac aatatgctgt tgttatgggc caaaaaagtc aactattctt tgaattgaca
    22561 ccagcagata cgtttctttt atttaaagaa ttatatgata tatctaatga agaatataag
    22621 aaaaacttgg attactttat cgaattattt gaggtatctg actatttaaa tgttcaagtt
    22681 aggacgcttt ctttaggaga aagaatgaaa atggaactaa tagtagccct tctacataat
    22741 ccaaaaatat tatttttgga tgaaccaact ataggcttag atgctatagc ccaaaaacaa
    22801 attaggtatt tcctaaaaga agtaaatgaa acaaaaggaa ctactattat acttacttct
    22861 cattacatgg aagatattaa gagtctctgt agtagaagta ttgttgtaga aaatagccgt
    22921 aaaatatatg atggttctac agagaaacta tttaattatt ttcaaaaata taaaaaaata
    22981 acagttagtt tttccaatga aactaacatt gtatttccaa aagattgtaa agttgttgaa
    23041 caaacaaatc ataagatatc agtaattgtg ccaaaagaaa gaggaaatga aacgattaaa
    23101 tggatttttg ataaatatga tgttaaagat gtaatgattg aagaagaaga tataggtagt
    23161 attgtagaga ggatatataa gaaaggaagt gatgagtatt atgagcaact ataatgaagc
    23221 aagttcaaat gattcaatgt tttataaatt taaacagagt attagaaggt attatgaagt
    23281 agccaaaatt aactttaaag tgcaacttat ctggagattt gatgtggtgg ttaatatggt
    23341 gtttacgatt gtaaaaattt tatttgctta tattttatgg aaagcaattt ttggtgaaaa
    23401 taaaatagtc tctggtttta catttaactc tatgttatct tactatataa taagctcatt
    23461 tttagcaggt attgatatgt caaagagtac cagtgaagag atatgtaatc gtgtaaaatt
    23521 gggcaccttt tcaaagtaca tgattattcc aattaatgtt caaaattatt ttattgctaa
    23581 aaattttgga atgacatgtt tttattttgt atttaatatg atttctgcat ttgtatggat
    23641 ttttatattt aaaatagatt ttgcctttac atcaaatcca gttcaaatat taatttcaat
    23701 tttgatgatt tttctagggt ttatttttat gatgaaactc cacttcttta ttgggatttt
    23761 gtcatttaaa tttcttgaga ttagtttttt aaaaatgata attgaaaata ttgttgaatt
    23821 tattacagga acaatgatac cacttgtact cttaccagaa actatagtaa cagttatgaa
    23881 ggtatttcca ttttattata caacatattt gccatctatg ttactaatag gtagaaacag
    23941 caatgaggca atacaaggat taattattct agcattatgg gttttatttt tttctgtagt
    24001 aaataaagtt atgtataaaa gaatgagaac attatttgat ggggtgggta tatgatgaaa
    24061 aaaaatttga aaataatatt tatgttatta aaaatgaaat tatcaaagat gatggtattt
    24121 agattcgatt tttttggagc attttttgta gatagttcat tatttatatt acaacttcta
    24181 atgtttaata gtatatattc tcatgtagac tcaatagggg gatggcaaca aggagagatg
    24241 ttaatattta taggaacttt ctcattaata aatgcgataa atatgacgat tttctttttt
    24301 ggtatttatg atattccacg aaaaatccaa gaaggagaat tagactacta tattacaaaa
    24361 ccattagacc cactatttag gttaacattt gaaaatatta atattggttc atcaccatta
    24421 attctagcaa gtatacttat tgttttatat ggaatatctg agttaaactc agagataact
    24481 ttagttatga taataatata tattttcatg gtgttattga tgacattact tttttatgat
    24541 gtatgtatca tacttagaac agtttcattt tttgttatat catcttctgc gataatgaga
    24601 ttagaagata atttattgcc aatgaatatg aaaattcctg gtgtaatata tgaaggtatt
    24661 tttaaagtat tattctattt aatcttacca tatggaatta tgtcgacaat tccgactcaa
    24721 attttggctg ggacaataac aattaatgga ttaatatact caattttaat tgtatttttg
    24781 tttacattgt ttatgtggag attttggaag ttaggtatga gacattataa aagtgcaagt
    24841 agttaataaa ttagtaaaaa tagacaatgt ataactatat ataaatacgt ttcatatgac
    24901 actaaactat gtgaacaagt atttgcgcta aaggcactga aagctataaa atgattaaag
    24961 taaggattta aaagtttctt tagtagaaat ataattgtgt aaaaaagcaa gattaattaa
    25021 aactatatcc aaataattag atataattct tatgcagaaa ggaggtctgt aaatgtctaa
    25081 ttgtttggaa tatattttaa aaataattaa tgtacagaaa aataaacaaa atgagtgatg
    25141 tatattattc agaaaatcat gaacaagata atctttatga gcaagataat ttactggcac
    25201 aaagatttaa tttatttact ctattgaagt ttgcatttcc tactattttt atgatgattt
    25261 ttatggggtt gtatacaatc gtagatacta tatttgtatc aagatttatt aatacaaatg
    25321 ctctatcagc aattaatatt gtatgtccaa ttattaatct tatagttgga attggaacta
    25381 tgcttgccac tggaggaagt gctattgtag cacgtaagat gggaaatggt gatattgagg
    25441 gagcaaataa agctttttct ttaatcgtat tatcaggagt tgtaattggg gtaataatta
    25501 ctggtatagg tattgtattt atggattata tcattatatg gttaggagca agtgaagttt
    25561 taattaaata ttgtcgttca tatcttttta ttatcttggt ttttgcttct gcaaatatac
    25621 tacaagtatt atttcaatgt ttatttgtaa cagctggaaa gcctcaattt ggattatggc
    25681 tagtgttagg tgctgggtgt gctaatataa ttcttgacta tgtgttcatt gttctgttac
    25741 aaatgggtat tagtggagca gcacttgcaa ctggagtagg atacctaatt cctaccattt
    25801 caggtatggt tttcttttca aaaaataaag ggttacttaa attttgtata cctagactag
    25861 ataaaagaat attatttgaa gcttgtttta atggttcatc tgaaatggtg ggtcaactat
    25921 caacagcagt tactactttt ttatttaatg ctatgatgat gaaattaatt ggtgaagatg
    25981 gggttgcagc tattacaata attatttatt ctcaatttct tttaacttcg ctttatatag
    26041 gtttctcaat gggtgttgca ccaataataa gttataacta tggaagtgaa aataatacgc
    26101 agttaaatca tgtttttaag atttgtatat tatttatttc agtagcatct ttattggtat
    26161 ttatcttttc tatatcatgt tcaccaatca ttgtagagat tttttctcaa agaggaagcc
    26221 gagtttatga aattgcaagg tccggatttt atatattttc ttttagtttt attttttgtg
    26281 gatataatat ttttacctca tctatgttta cagcattatc aaatggaaag gtgtctgcaa
    26341 tattatcttt tctacgtaca tttggattta taactatagg tttattgata ttgccaaata
    26401 tattaaatat aaatgggata tggttagcag taccaagtgc tgagatttta accttatttt
    26461 taactgtttt ttgtatattt aagtataaga atagatataa atatatgtag atattaaata
    26521 aatagcttag atagatattt tatgttttaa taagtaattc aattagtggt agatatatac
    26581 tattgaaaat taaagttata attgatataa agaattaata aaaataacat ataaaagttt
    26641 aaaagggagt tgaacttaaa gtttgattag aaaaagtcaa ttttaagaca actcctttta
    26701 ttttactatt gtattaatct gtatctgtaa gtgtattagt ctaatattat aaactttgga
    26761 tgaaattaat tttctatagg ttttaatgta tcatacactt tattttaaag aaacttatct
    26821 taattttcat agtgattgaa tttgtctatt agagatgtta ctattagtaa tgtaaaagca
    26881 agagtagtga atataaaaaa caagatagtg atactgcaag attagaatat aataaatttt
    26941 tatggagaga tttcaatatg gatacatgtt ttaataaaaa aatattactt gttgatgatg
    27001 aaaaggatat agtagattta attgaagaag tactcataaa tgatggtttt aaaaacatta
    27061 ttaaagctta taatggtcta gatgctattt cgctgtgtaa gatagcatgt ccagatgttg
    27121 tcattcttga tataatgtta ccagatatag atggtataga agtgtgtaaa aaaattcgag
    27181 agttttcata ctgttctatt ctttttttat catcaaaaaa tgatgatatt gacaaaatac
    27241 taggtcttag tagtggggga gatgactata taacaaagcc attcagtcca agagaaattg
    27301 cttttcgagt taaagcgcaa ttacgtagac aacagtatca aagcattgta ccatcagata
    27361 gtgaagttat taaaatagga gatattacta ttgatataga aggaaaccgt gtatataaag
    27421 atagaaatga gattgagtta actggaaggg agtatcatct tttaagctac atggctcaaa
    27481 atgtaaataa aattatagga aaagaaagac tctatgaaca agtatgggga gtatatagta
    27541 gtatttgtga caatacaatt atggtgcata tacgacatat aagagaaaaa attgaagata
    27601 acccctcaaa tcctaaaata cttataacag ttaaaggact aggatataaa cttgtgaata
    27661 gaatcgatta gaatagattt taatattaat gaagatatct caagttgaat ttttagttaa
    27721 tgaggcattc ttttatgggt gaaatcaaat gtattttcgt tatctcaaca atgaagaaga
    27781 ggtctatctc tattttgaga tagcctcatt aagtttatat cctggtaatg tactttatgt
    27841 tctaataaaa tttttttagt ttatttgcag tgaaacatta actagaacat taaaatttgc
    27901 attgaaatac caattaaata atattgtata ttgtgtataa acttatacta attgtttttc
    27961 tatattaaat actttatcaa tccaaccttt ataaaatttt tcttcatggg aaactaggat
    28021 tatacttcct ctaaactgtt tcaaagcatt ttgtaaagca tcctttgtct ctgcatcaaa
    28081 gtgattggtt ggttcatcca gaataagaaa attacaagga gataacatca tacaacataa
    28141 tttaacctta gattgttcac caccacttaa agtagataca ctccttgaaa catgctcttc
    28201 cttcacacca catctggcta gatgacgtct aatctctttt gtatttaatt ttggatattt
    28261 atctgctact atttgaagtg gggttttatc aggattttcc cattttaaat cttgctcata
    28321 ataaccaatt ttaacttgtt ctgaaaactg gaaatctcca gatatacgag gaatatcttt
    28381 gactaatgtc tttaacaagg tagatttacc gattccatta aaaccagtta taactatttt
    28441 ttgacctcca tcaacagaga aatttaattt tggaagtaaa gaatagtagt atccaacttc
    28501 aagatttgtt atagtaagag cattttgagc cgatatttca atttctgaaa attgaatatt
    28561 tggttttcct gtaaaactag gaggagctat tctttctatt ttatccaatt gtttttgtct
    28621 tcctcttgca atttttgaat ttactccagc tttattttta cgtataaatg tttcttcttt
    28681 ttctattttc ttttgttgtg cttgatacct tctaatataa tcttctctta aatgtgattt
    28741 ttgtttaagg aactctgaat attttccatg atatttctta atcatgccaa attctatatc
    28801 aagaatacct gtagaaattt tttctaaaaa gtcaaaatcg tgggaaacta caataaatgc
    28861 cccattaaat gtatttaaat aatttgagag ccattcaaca tgctctttat ctaaaaagtt
    28921 tgttggttcg tctaataata gaacatcatg gttagaaagt agtaattttg ctaaaattac
    28981 ctttgccctt tgaccaccac taagctctct aacaacacga ttcattccta ttgaatctaa
    29041 tccaagacca tttgctattt tatttatttc attatctata gaatagaaat tacttgctat
    29101 tagttgttcc tgataatctg atgctttgat tagatattgc tcattttcag atatagcact
    29161 tttttgatag agtaaattca tttccttttc tattttataa agttcttcaa atgcagtgtg
    29221 taaatagagt gatattgttg tatctctatt gatttctgca tattggtcta aatggcctat
    29281 attgatatta ggttgccact tgatttctcc tgaatctgga acaacttctc ccaataaaat
    29341 tttaattaat gtacttttac ctgtaccatt ttggccaact acacctatat gttcaccttt
    29401 gaataaatca aagttagctt tctcatacag tgatttatcc ataaaacatt gtgataaatt
    29461 agttactttt aataaactca taattcaaac tccttttctt ttattaaaaa atttatggaa
    29521 ataaaaaaag cagaggaatg gcattgtaaa atgccgacct ctgcttttgg aaaaacaaaa
    29581 ggtcatagac aagcattgtt gtctatgacc agaaaatcta tattatctat cggcaaatag
    29641 gtaattttaa ataagcatag ccaaaaaact atactaaacc tatatttgcc gatgaagata
    29701 gaaagcttta agctttcaga ttaacctcta cacaacgctt catcgtatac atttgtgtag
    29761 agttaagttt tctaacaagt ttaactaatt ctatataaat cataattatt cacatcctaa
    29821 tcttagtatt aattctagtt tatctgtatt taaattgtac ttttgtactt tgtggattat
    29881 cttatttatt taaaatatgt tttattaatt atagcttaag ttatgttatc ataatactta
    29941 gttatagtca ataagaaagt tatatttact attattatat taatttagta aatctatcat
    30001 tacaaagtta tttgaagact cgctatcaat aaaattttat agtctataag aaaattaaga
    30061 ttatgagttt tataattttg atatagggat actattttca taaatattac aacatgtaga
    30121 agtatatgtc tattattgtt gaattttcaa tgatatatta aggttctaat atattataca
    30181 aaataaaaac attaattcaa cttaaataat tttaagtatt atatgtgttt tgattaaaga
    30241 aaactaaaat tttaaggaaa aataacatat ttgtattaaa ttttattgaa atgattaaat
    30301 ttatttactt aatgtaaatt attagctaaa attgtattaa ataattaagg aggtgagtag
    30361 ctctggatga aatagattta aaaataatta attctctaaa aaagaatagt agggcttcaa
    30421 cctctgaaat aagcagacaa attaatttat cagtaccagc agtctcagag cgtataagga
    30481 aaattgagca gtcaaattta attcaaaagt acactattca aattaatcgg gaaaaaacaa
    30541 aatataagct tttggctttt atatttatca atactgattt atctaaaagt atgaaagaat
    30601 ttaagaaaac tatattggaa tatgatactg tattagaatg tcatcatatt tcaggagagt
    30661 atgattactt aataaaagta ttagcagaag atacaagtaa tcttgaagag tttatatcag
    30721 tgactttgaa ggaaattggg gggattcaaa aagctaatac aaccattgtt ttatctacaa
    30781 ttaaagaaga atttaataca ataaaagata ttttttaaat aatttactag taaagtgtta
    30841 attatatttt aggaggaaaa tagaatatga aagttttagt ttttttagca aaaggttttg
    30901 aaactatgga atttagtgta tttgtagatg ttatgggatg ggctcgtaac gattatgggc
    30961 atgatattga tgtagtgact tgtggattta aaaaacaagt tatgagcaca tttaatatac
    31021 aagtattagt tgataagacg atagaagaag tatgtgttga tgattatgat gctctagcta
    31081 ttcctggagg atttgaagaa tttggatttt atgatgaagc atatgattca tcttttttaa
    31141 atctaataag ggagtttaat tcaaaagaaa aaataatcgc ttctatttgt gtggcagcat
    31201 tgccagttgg aaaaagtggt gttttaaaaa atcgtaaagc tactacatat catttgaaaa
    31261 atggtaaaag acaaagacag ttaagtgagt ttgatgtaaa tgtagttaat gaaccaattg
    31321 ttgtagataa aaatattata acctcatatt gtccagaaac agctccacat gtagctttta
    31381 agcttttaga aatgttgaca tctaaagaac aaatggatga agttaaatta gcaatgggat
    31441 ttaaactgta atggtttata gattttctaa gtaatcagaa ccccagtcac acatggaatc
    31501 taaaattgga ataatactct ttccaaaatc agatagcgag tattctactt ttggaggaac
    31561 aacaggataa accactctta taattaaacc atctgattct aattcacgta attgttgagt
    31621 taacatctta ggcgttgctt taggaattaa tttttttaat tcattgaacc tcaatatagt
    31681 gtctttaaga tgccaaagta taagtgtctt atatttacca ccaatcaatg caagtgttgc
    31741 ttctattggg caactgtaat tatctaaaca ttttttcatt tttgggctcc tttatttatt
    31801 ttaaagtatc tttttaggta ctatattaca aaaaagtgca ttattgtaat atagtaccat
    31861 agtgataaaa ttatagcata ggttaaataa atcatcaact tagcctaata aaacaatagg
    31921 gggtaaataa atgaatttcg ttgaacttgc aaaaaaaaga tattcttgcc gtaattatca
    31981 agatagaaag gttgaaaaag aaaaacttga gaaggtttta gatgttgcaa gaatagctcc
    32041 aactggtggt aatcgtcaac ctcaaagatt gattgttatt caggaaaaag aaggtataaa
    32101 taaactttct aaggctgcca atatatatga tgcgccatta gcaattcttg tatgtggaga
    32161 taaagacaaa gtttggacaa gaccttttga tgggaaacaa cttacagata ttgacacaag
    32221 tatagttaca gaccatatga tgttacaggc aactgaactt ggattggcaa gtgtttgggt
    32281 gtgctatttt aatccagata taattagaga agagtttagt ttgccagata atctagaacc
    32341 aataaatata ttattgatgg gatatgaatc taagatacca gagagcccag agagacatga
    32401 aaaaactcgt gttcctttaa gtgaaattgt ttcttatgaa actctttaat tataaaatta
    32461 agttattcat aggataaatg taataaagtg tttgttataa acaaaattca aaataaataa
    32521 tatctacata taattaattt tagtgaagta tatctagttt aactagaatg tatacttcac
    32581 taatttattt attcaaaata tttatgagga ttttaatata ttaactaaaa tatatcaatt
    32641 gaattaactt ttaaatctgg aaaagcactt gaaatatagt gttttatatc atttaaatgg
    32701 tcttgaattt gcttttctga tattttatca ggtccatata caaaatacat aatattttta
    32761 gtatcttttg ttatagctgt tcgattatca gggccattaa gaatactaga taatatacca
    32821 atattatctg ataaaaataa atcatctttt gttaaaatat gttctttacc acctatacca
    32881 taaaaatgtt cacttccatt tgctaattct attttcaaag gtaattccat tttatcaagg
    32941 tcatgacctg ctgttagaag aagatttttc aattctgcta aaaacattga ctcaattgtt
    33001 acacctacat ctgggatacc ttttgatttt aatagaatag attctaattg aagcaataca
    33061 gggtaagttt tcttgaattt tttataatac tttatataac ttgaaacagg ctctgtttta
    33121 attttttctt tgcgattgta ttctgggtgt tgttctataa tatttttaat tgtagagttt
    33181 ttaagaacta aaaaattttc tttattaggt tttgaatgtg taatatttat aaccataact
    33241 ccaaatttaa tattgggata aatttcttta actttatgtg atacctctaa cataatatag
    33301 actccttttt attttatatt ttatgatata atcttagcaa attaaaagtg gattttatag
    33361 ttccattttt atagtaattt tatagaacca cttttggagg tattagaatg tggattacga
    33421 ttaatagaaa tagtaatata tcattatcaa gacaaattta ttgtgagata aaagatatga
    33481 ttctggatgg aagcttaaag tttgagcaaa aactgccatc atctaggact ttatcaaaag
    33541 aactatctgt atctcgtaat acagttttag atgcatataa tcaattaatt gcagaaggat
    33601 atttggaaac aaggaatgga tatggaacaa ttgtagctaa aggaatatca gggcataaag
    33661 ttgattttaa gttaaatgat acttttagag atgaaaaaga tttacatact aataaacaaa
    33721 aaaattatat agattttcgt tcaggagttc cagaattaaa actatttcca cgcaaagaac
    33781 tttcaaagct atataaacaa atactgtatg atttatcaga ttcggatttc agatatggaa
    33841 gtacagctgg tgtatgggtt ttaagagtgg aaatatctaa gtatttattt cgtactagag
    33901 gaattagatg taatcccaaa aacattatga ttgtttctgg ttcaacacaa ggtttatctt
    33961 taatttcaca gcttttatac aaaagtaata aaaaggttgc tgtagaagac cctattcata
    34021 aaggcttatt aaaggttatt tcatctattg gatattcagt tgttggaatt aaagtagatg
    34081 ataagggaat gaataccaac ttaataaaat caataaaggg gatttctttt gtttatacta
    34141 caccttctca tcaataccca ttaggaggga ttttacctat tcaaagaaga ctagagctta
    34201 ttaaatgtgc aacagagaat gattactata taattgaaga tgattatgat agtgaattta
    34261 gatatgaggg tcaaccaatt agttctcttt atgaacttag cccaaataaa gtaatttaca
    34321 taggttcttt tagtaaaata ttatctccag ctattcgtgt tggatttatg ttattaccag
    34381 acaatatttt agaaagctat aaaaccttaa aaatgtactc tgatgttcat acagaaacaa
    34441 tattgcaaca tgtattagct gaatttattg gaaatggagg tttagagaag tacatattta
    34501 gaatgaagaa gttgtacaat agaaaacgta agtacctcat aaaagtttta aacacggaat
    34561 ttaaaaatga atttaaaata aaaggtgaag cagcagggct tcatatagtt gctcatttct
    34621 ataatgttaa atttacggaa agtttaattc ataaaatttt tgaagcaggt ataaaagttt
    34681 atcctataca acaatatgca attgagaata tattagaata tgactatgaa attatactag
    34741 gttatgctca tcttagtttt gatgaaattg aaaaaggtgt aaaaatactc agcaaaataa
    34801 tacatatgaa tcaaggtaca tagataaaac atgtagcaat ctacatataa tagatgtaat
    34861 taagtttaaa ctttaaaaga aatatatatt aatatttttg tataaaaata cctgatattt
    34921 ttttatcgat actttattgc tatacactaa attaagatag caatttatat taagaaaaaa
    34981 ctttttgcat aggttataat acttaaaagg agaggataga gttgaaaaca aatacagatg
    35041 ttattatgga gataattgat tatatagaag aaaatcttac agaaaatcta aatttagata
    35101 aaatagctta tattgctaat tattcaaaat accatttaca cagaatgttt acaaatgttg
    35161 taggatgtac tatccatcaa tacatacaga ggaggagact tactgaagca gctagacaac
    35221 ttatatttac agacaaatat attatagaca tagctattac agtaggatat tctacacatc
    35281 aatcttttac actagcattt agaaatttat ataaagaatc tccacaagta tatagaaata
    35341 aagatgaatt ttatcctatt caacagagat ttgttttaaa tctaaatcat caaattcaaa
    35401 gtgaaaaatg tatttcttat gcaaatatga attataaaca aagaagagat gaaatcaatt
    35461 cttatcttaa ctttaatatt aattgtgagg tgaaagtagc atgagtttag tgccacatgt
    35521 aattgaacaa acaggtcaag gggaaaggtc ttatgatata tattcaaaat tattaaaaga
    35581 tagaattata tttataggag aagaaattaa tgatgctatt gcaagtttag tagtagctca
    35641 attactgttt ttagaatcag aagacccaga ttcagatata attatatata taaatagccc
    35701 tggtggctct gctacatcag gatttgctat atatgatact atgaattatg tcagatgtga
    35761 tgtatcgact atttgtattg gtatggctgc aagcatgagt gcttttttac ttgcaggagg
    35821 aacacatgga aaaagatgtg ctttacctaa ttcagagatt atgattcatc agccaatggg
    35881 aggagctaaa ggtcaagcaa cagatgtaaa aatagctgta gataatatat tgaaaataaa
    35941 agaacgatta gataaaattc tttctgaaaa tacaggtaaa tcaatagaag atattaggag
    36001 agatacagat agagataatt ttatgactgc actagaggct aaagagtacg ggctgattga
    36061 ttatataatg aataggaatg aataaagtat caaagtatca tattaaaatg tctgttttac
    36121 aaatatatat ataatattaa ataagagtgt ctcaaaatga actttttagt ttatgggaca
    36181 ctcttttttg tatgaaatta aatatggttt tatcatttca acaattatta ccaaatttca
    36241 agtttaataa attctactat aaaaaataca taaaagataa ggttctttag taactttctg
    36301 tcgtcaaaag tttttataaa tttaataaca aaacaagaga aaataccata tattacttat
    36361 gtctgcaata tatagaagac aaaggagttg tacattatga ttacaataag tttgtgcatg
    36421 attgttaaga atgaggaaga agttataggc agatgcttag aatgtgtaaa ggatatagta
    36481 gacgaaatta taattgtaga tacaggttct acagattcca caaaagaaat agtctcaaaa
    36541 tatacagaca tggtgtacga tttcgaatgg atagatgatt tctctgctgc aagaaatttt
    36601 tcattttcta aagcttctaa agactatact atgtggcttg atgcagatga cataatttta
    36661 gaagctgata gagaaaaatt attaaagatt aaagaaagct tggatacttc cattgatatt
    36721 gttatggcaa aatacaatgt atcctttgat gaaaatggta acccaactct ctcgtattat
    36781 agagaacgat tgtttaaaag aagttctaat cataaatggg ttgaccctat tcatgaagta
    36841 gtacctcttt ttggagaggt attttattct gacattgcaa tatctcataa aaagcttcat
    36901 agacaggacc ctctaagaaa tcttagaatt tttgaaaaaa tgatttcaga aggaaaaaca
    36961 ttggagccaa gacaccaatt ctattattct agagagttgt actataatgc taggtataaa
    37021 gaagcaatag aaggttttac taagttttta gactcatcaa gaggatggat tgaggattgt
    37081 atcagtgctt gcagagattt agccacatgt tattacttaa ttaatgatga aaaaagtgcc
    37141 ttatattcat tgtttagaag tttcgaattt gatgagccaa gagcagaaat ttgttgtgac
    37201 ataggaaagc atatgtttga tagacaaaaa tataaagaag ccattttttg gtataaggta
    37261 gcattaacaa gagataagaa tgatactaat ggaggtttta agtcaaatga ttgttatgga
    37321 tatataccat ctatacaatt aagtgtctgt tatgacaggt taggagaatc agataaagct
    37381 atttattatc atgaaaaaac aaaagaaatc aaacctaacg atagtgctgt tttgcacaat
    37441 gaaaattatt ttagtaaatt taaaaatagt tgataggtca caatcatact aaatttgaca
    37501 tattatatat agagcttaaa agctcaaata tatcaggagg tgcttttaat aatgagtaga
    37561 aataaatatt ttggaccatt tgatgataat gattacaaca atggctatga taaatatgat
    37621 gattgtaaca atggtcgtga tgattataat agctgtgatt gccatcattg ctgtccacca
    37681 tcatgtgtag gtccaacagg cccaatgggt ccaagaggta gaaccggccc aacaggtcca
    37741 acgggtccaa caggtccagg agtaggggca acaggcccaa caggaccaac cggtccgact
    37801 ggtccaacag gaaatacagg gaatacagga gcaacaggat taagaggtcc aacaggagca
    37861 acaggggcaa caggcccaac aggagcgaca ggagctatag ggtttggagt aacaggtcca
    37921 acaggcccaa caggagcgac aggagcaaca ggagcagatg gagtaacagg tccaacaggt
    37981 ccaacgggag caacaggagc agatggaata acaggtccaa caggagcaac aggggcaaca
    38041 ggatttggag taacaggtcc aacaggccca acaggagcaa caggagtagg agtaacagga
    38101 gcaacaggat taataggtcc aacaggagcg acaggaacac ctggagcaac aggtccaaca
    38161 ggggcaatag gagcaacagg aataggaata acaggtccaa caggagcaac aggagcaaca
    38221 ggggcagatg gagcaacagg agtaacaggc ccaacaggcc caacaggggc aacaggagca
    38281 gatggagtaa caggcccaac aggagcaaca ggagcaacag gaataggaat aacaggccca
    38341 acaggtccaa caggagcaac aggaataggg ataacagggg caacgggatt aataggtcca
    38401 acaggggcaa caggaacacc tggagcaaca ggtccaacag gagcaacagg cccaacagga
    38461 gtaggagtaa caggagcaac aggagcaaca ggggcaacag gagcagacgg agcaacagga
    38521 gtaacaggtc caacaggagc aacaggggca acaggagcaa atggattagt aggcccaaca
    38581 ggagccacag gagcagcagg aacacctgga gcaacaggtc caacaggagc aacaggccca
    38641 acaggagtag gaataacagg agcaacaggg gcaacaggag cgacaggtcc aacaggagca
    38701 gatggagcaa caggtccaac aggagcaaca ggaaatacag gagcagatgg agtagcaggt
    38761 ccaacaggag caacaggagc aacaggaaat acaggagcag atggagcaac aggtccaaca
    38821 ggagcaacag gggcaacagg agcagatgga gcaacaggtc caacaggagc aacaggagca
    38881 acaggagtgg caggagcaac aggagcaaca ggtccaacag gagcaacagg agcaacagga
    38941 gcagatggag caacaggtcc aacaggagca acaggagcaa caggggcaga tggagcaaca
    39001 ggtccaacag gagcaacagg ggcaacagga gttacaggag caacaggccc aacaggccca
    39061 acaggagcaa caggagcaac aggagcaaca ggtgctagtg caataatacc ttttgcatca
    39121 ggtataccac tatcacttac aactatagct ggaggattag taggtacacc tggatttgtt
    39181 ggatttggta gttcggctcc aggattaagt atagttggtg gagtaataga ccttacaaac
    39241 gcagcaggaa cattgactaa ctttgcattt tcaatgccaa gagatggaac aataacatct
    39301 atttcagcat acttcagtac aacagcagca ctttcacttg ttggttcaac aattacaatt
    39361 acagcaacac tttaccaatc tactgcacca aataactcat ttacagctgt accaggagcg
    39421 acagttacac tagctccacc acttacaggt atattatcag ttggttcaat ttctagtgga
    39481 attgtaacag gattaaatat agcagcaaca gcacaaactc gattcttact agtatttact
    39541 gcaacagctt caggtctttc attagttaat actgtagcag gatatgcaag tgcaggaatt
    39601 gcaataaatt agattagata agaaaaggct tctaatatcg tattgatatt aggagctttt
    39661 ttaagaatga ttgatgaaca tagttttaat attaattagt gcgcatatta taaaatacta
    39721 ttatataata taaaataata acattaaatt ggaaatatag aattatctag gggtgatact
    39781 atgaaaaata agattgaaat atcaatgaac aactttgtaa aaaattatca taaatcaaat
    39841 aatataacta caaagtggca agaacttttg tttgcttatg catctgctga agatgatatg
    39901 tttcagaagc taaaaagtgt tgtaggaaca tctcatgcta tgccaaaaga ttttctggaa
    39961 aatggaaaaa ctataattac atattttata ccttttgatg aaagtgtaaa taatagtaat
    40021 attggagggt ttgaatgttc tgaaatatgg gcaagagcgt acatagaaac taatatgttg
    40081 atttcaaatt taaatgattt cttatgtgaa gaactagaga agataggggc taattcatat
    40141 gctattcctg ggtcgtataa ttttgacagt gaaaaattgg taagtgactg gtcacaaaga
    40201 catgtagcat tcatagcagg tcttggaact tttggtttaa ataatatgct tattacagaa
    40261 aaagggtgtt gtggaagaat aggaagcata atcacaagtt tagaattaga gccaactaaa
    40321 agaccagaaa atgaatactg cttgtataaa cataataata gttgcaaaaa atgtgtcaat
    40381 aaatgcgtga aagaagcttt aaaagaagat ggatttaata ggaataagtg ttatgaaatg
    40441 tgtatgataa atgaaaaaaa atacacttat ataggtggat gtgatatttg tggaaagtgt
    40501 atagttggag ttccttgttc agtaataaac ccatcaagat aatggattta agttgactaa
    40561 taattttaaa gatagtttat aatgaaaaaa ttttagttat caaaataaat ataatataaa
    40621 aactaaataa atgtgtttaa aaaatggata aataatttgt gttgattgac aaccagttat
    40681 actgttgata gacttatatg tatcgctgtg atatataagg agggttgaga ttttatgttt
    40741 gatttaatct ttatttttgc atagcaaggg ctattgcaac tatgaaattt aatatataaa
    40801 tagccctttg ctattcctaa tgaaaaatta ctatttaata ggagagcaaa atgagctata
    40861 aaaaagcaat acatatatta ccagaagaat tacttgaatt aatacaggaa tatgtagatg
    40921 gtgaatgtat ctatattcct agaaaatcta ataataaaaa agaatgggga agtaatacac
    40981 ctactcgtga ggagttgtca attagaaata tgcagattta cgaagactat caagttggat
    41041 atgatttgca atatttatcg gaaaagtatt atttatcttt gaaaagtatc caaagaattg
    41101 tattacaaga aaaaagaaaa gatatctaag gatgagccag tatagtttta taattatact
    41161 ggctcatttt cttttgataa aagtgtttga ggtatagttt cttttaagtg gatgatataa
    41221 tttaagtaat ttcaataact tatacagtag ctaacaaagc tggttgtaaa gtatctaata
    41281 agaagtagta gctttttata tgtttgaaat taaaatttat taaaattagg aggtcttgtt
    41341 ttgaaaaaaa tacttgatta tattccacct tttcataact ttctattaat ttagtaatct
    41401 tatagaaagg aaattgcatt tatgaaaaaa attacttggg aggtggaata tatctcccag
    41461 ttacctgtaa ttaggtattg taaaaaatgt ggaaaaaaga ctgaatatat ttgttcaggt
    41521 ttatttaggg ttaatgctca acataaatat ttggatatat ggttaatata caagtgttca
    41581 aattgtgatt caacatggaa ctcaactata tattctcgtg ttaatccaaa aagcttaaat
    41641 ccagaaatac tagaacaatt ccatacaaat gattataatc ttgttaagca atatgctatg
    41701 aatatggaac ttttacatag aaatggagca gaagttggta ttccagagta taaaatagta
    41761 ggacaagaaa ttaatattaa tgaccttaca caagttcata ttattagtaa atatccatgt
    41821 cagttaaagg tatcaacatt attacgtgag aaactaggtt tatctaggaa ggtatttgac
    41881 gaaatgttgg attgtgggat tattagaagt aactcaggag ttgatttaaa gaaaggtaaa
    41941 ttaaattatg aaattatgtt agatataggc aaggagaagc aaaagtcttc aaattgatta
    42001 gaataactaa cttaatatat tttcaggaac atcatttaaa aaaatagtga ctttaaaaaa
    42061 tttaaagcca ctatttttta atatgtttta tctatataac tattattttt ctaggttttt
    42121 taatatttcg taatagtgtg ttgtggctat ttcacttgac tcgccttttt tacaaaaaga
    42181 taatttagat agttttggaa ctacacgttc aacgacaatt ttattaccta tcattttaga
    42241 ttcaagtatc ttcaatgctt ctaaaaatct cttatccttt tttgcacgat tataaaatga
    42301 taaaacgtag acataaagga ataggttata attacggaaa ggatattcaa cttgcataaa
    42361 taatgtgcca attccatagt gacaagggcc gattggtttt ttaatagtcc aatggtcaag
    42421 tagaaaatct acagctttgt caagttttga ttctttattt agataattac taaaacggaa
    42481 tgcatttaat atattaagag ttggtagtgg atttgagtat tcagtttctg gacctcgacc
    42541 aaaactaaat ttattgcaac gccacccacc atcagtatac tgtgtatcta aaaaatgttg
    42601 aaacgttttt tgcattctaa tgtcagatgc atatcccata tgacagagta cgttagcagc
    42661 atttgcagta tgacaagggt aaatacctcc atttggatat agtttgaaac gtccatcttc
    42721 tcgccatgtg ctaaatatca ggtcagcaca ttctttaagt aaagtatcat cagggttcac
    42781 acctaattct aatagataaa gtacactatc aagagtagag aaaggagaac cttttattaa
    42841 acgcttatca ggtgtagtcc aatagtctgc accattatca tacctgtgtg ataatattat
    42901 ttcaatatct gataaagatt gattttctac attcattttt tactccattt catattatat
    42961 tctattaaat ctatcaaaaa ctttattata atattattta tatttataat tgatttattt
    43021 tatttaaaat tgcatttata gctgtatcag gaacaactgc taaatcttct gcattgaagt
    43081 aataaactat attagaatca aataatatat ttgaatttgg aggaaattca tcatctccaa
    43141 accaaagtat aaataccata gatgtattac ccatatatgt aaacctataa gctaaatctc
    43201 ccatgtttac tttttcagct ccaattttct ccataactaa cttatatttg tctatttgag
    43261 atgtaaaaac ttctgaaagc ctatatagag tcctgtttaa aaaatttgga taataaacat
    43321 tgcctcctgg tatttcttta aaagttacat atttattagt tctaggaata cctttagcat
    43381 tgattaaata tctaactatc aagattttaa gctcaaagtt attgcaaagg ctaccattac
    43441 tattccaaac ttctccactt ggatagtcta taatatattg tctatcaaaa aaattgagtg
    43501 tgaatctatt taaatcatta ttgaaaggta tattacttaa attactaatt gtatgagggt
    43561 ctaattcttt gagttttttt cgaacatagt caaatggaac attataatta ttttttgtta
    43621 tcttttcatc cataattttt tcctccaatt taaacaatta aaagtatatt tataaaaagt
    43681 tttcttatta ttaatttt
//
LOCUS       DAMJVG010000028        43329 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.028, whole genome shotgun sequence.
ACCESSION   DAMJVG010000028 DAMJVG010000000
VERSION     DAMJVG010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 43329)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43329)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43329
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.028"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            265..729
                     /locus_tag="PC512_001636"
     CDS             265..729
                     /locus_tag="PC512_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HDF2441382.1"
                     /translation="MATMTDIIEKFIKDLMEEDNSIQIQRNELANLFSCAPSQINYVL
                     TTRFTIDRGYYIESKKGGGGYVQIEKIRKSKDGHIRELLNEKIGSQISYKKAKELLEG
                     LKESDLINERELKLILYAIDDKSLCMPIYELKEKVRSNILKNIIIGLFSIEE"
     gene            736..1230
                     /locus_tag="PC512_001637"
     CDS             736..1230
                     /locus_tag="PC512_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrB/UvrC motif-containing protein"
                     /protein_id="HDF2441383.1"
                     /translation="MLCQKCNKNKASVYYNKIVNGEKTEMYLCSECAKENTEMNFNLD
                     MPFSMMDIFSNLGFQPKKELEEKLVCPKCNTTYSEFKNNGRFGCSECYNAFSSQVNPM
                     LQNIHGHIEHTGKAPKKSFYKISVENEIKELKEDLDRAIKNEEYELAAQFRDKIKYLK
                     GSID"
     gene            1246..2271
                     /locus_tag="PC512_001638"
     CDS             1246..2271
                     /locus_tag="PC512_001638"
                     /EC_number="2.7.14.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein arginine kinase"
                     /protein_id="HDF2441384.1"
                     /translation="MKENIVMKSRVRLARNLNNYPFPNKLDKECAMEIIEKVKNAFIN
                     SNLEQKEEFDFYKIEDLDQSKKMLMVEEHIISPDLAENDKSAVIVKKDKTISIMINEE
                     DHIRIQTICDDLNLEYAYSVANEIDDLLESSLEYAFNTKLGYLTSCPTNTGTGMRASV
                     MMHLPALSQLGYMDELYKISSQIGIAIRGIYGERTEALGNIYQISNQLTLGRTESNII
                     ENVSGLTKDAISKEIKAREILQKKLGIKLEDKIFRSIGTLENSRVMSSAEAMSHLSNI
                     KMGIEMNYIDKLDLRAIEQLMIGIQPAHQSIMYKSDDVENRDINRATYIRETLEKLRG
                     GMNCELQ"
     gene            2258..4705
                     /locus_tag="PC512_001639"
     CDS             2258..4705
                     /locus_tag="PC512_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HDF2441385.1"
                     /translation="MNFNRFTQRAKKAIDLAFESAKSLGHNIVGSEHILLGLLREEEG
                     IAAKVLSKVGFTEAYLEGKIVDMEGKGEEISEDIVLSPRSKQILELSGMFANKLKTNY
                     IGTEHILLAIIQEGEGIANKILNYAGVNDRTLAQLTIDMMGISDKNQYKAENSYTGNQ
                     NQAESKVLDKYGRNLTLYAKQNKIDPVIGREKEIQRVIQILSRRTKNNPVLIGDPGVG
                     KTAIAEGLATNIALGNVPETLKNKTLYSLEMGSLLAGAKYRGEFEERIKEVVDEVVKN
                     GNIILFIDEMHTIIGAGSTGEGSIDASNILKPALARGEIQVIGATTIDEYRKHVEKDS
                     ALERRFQPVMVDEPTKEDSIKILEGLRDKYEAHHKVKITDDAIKAAVELSTRYISDRY
                     LPDKAIDLIDEAASKVRLKENTPPSEIKKLELEIENIDKEKEEAVRCQDFEKAAKIRD
                     EQGLLKKQLEDVRERWNKSSKHSDLVDGEVIAEVVGLWTGIPVNKILEEEADRLLRLE
                     EILHNRVIGQEQAVKSISKAIRRSRAGLKDPNRPIGSFLFLGPTGVGKTELSKALAEV
                     QFGDENQIIRIDMSEYMEKHAVSRMIGSPPGYVGHDEGGQLTEKVRRNPYSVILFDEI
                     EKAHPDVFNILLQILDDGRLTDSKGRTVDFKNTIVIMTSNVGASTIGRQKTLGFSIAK
                     GDEEEKSQYEKMKENIMGELKQRFRPEFLNRIDDIIVFHSLNENHISKIVLLMAAKLQ
                     ERLKEMDIKLEMSDEAVKLISKSGFDLEYGARPLKRALQKELEDELSEAILKGNVKKG
                     SNVVAKVKDEKIVFETK"
     gene            4885..6258
                     /gene="radA"
                     /locus_tag="PC512_001640"
     CDS             4885..6258
                     /gene="radA"
                     /locus_tag="PC512_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HDF2441386.1"
                     /translation="MAKIKTKYVCQSCGYETAKWLGKCPECTKWNTFVEEIDQKSTKK
                     EVFIIDKSSSKPVSINSIESKEEERFTTDINELDRVLGGGIVKGSLVLVGGDPGIGKS
                     TLLIQVSSNVANLGKTVLYITGEESESQIKMRAKRLGINSENLYIFAENNLSIIESYL
                     ESVNPELIILDSIQTVFSPEISSAPGTVSQIKEGTSKFMKISKKMGISTFIVGHVTKE
                     GSLAGPKLLEHMVDTVLYFEGERYNTYRLVRAVKNRFGSTNELGVFEMRDLGLVELDN
                     PSKILISEKPKDVAGSVIISTVEGTRPMLLELQALVSPTSFGIPKRTSTGVDYNRVGM
                     LLAVLEKRVGLQIQNQDVYINIVGGIKINEPSIDLGIAISVASSFRNIPIDEDIAVTG
                     EVGLTGEVRAVSFIEKRIAECKKLGFKKIVVPRSNYDVVKETKGIEIWPVDNLRQAIN
                     IVLGRNQ"
     gene            6261..7331
                     /gene="disA"
                     /locus_tag="PC512_001641"
     CDS             6261..7331
                     /gene="disA"
                     /locus_tag="PC512_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA integrity scanning protein DisA"
                     /protein_id="HDF2441387.1"
                     /translation="MENFLDNKNMLYALKMISPGTPLRLGLNNVLRAKTGGLIVIATN
                     EDVMKIVDGGFAINAEYSPSYLYELAKMDGAIVLSGDVKKILFANAQLIPDYFIETSE
                     TGTRHRTAERVAKQTGAIVIGISQRRNVITVYRGNEKYVVEDISKIFTKANQAIQTLE
                     KYKTVLDQAVTNLNALEFNDLVTIYDVALVMQKMEMVMRVTSIIEKYVIELGDEGTLV
                     SMQLEELMGTTRIDQKLIFKDYNKENTEIKELMKKVKNLNSEELIELVNMAKLLGYSG
                     FSESMDMPIKTRGYRILSKIHRLPTAIIENLVNYFENFQQILDASIEELDEVEGIGEI
                     RATYIKNGLIKMKQLVLLDRHI"
     gene            7420..8514
                     /locus_tag="PC512_001642"
     CDS             7420..8514
                     /locus_tag="PC512_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HDF2441388.1"
                     /translation="MIRKVTRILFILLGFTIGITTYLTLMKDFEILTFGKETYGYIAA
                     VVAGIIIAILGYLIEPWVVNKVKEIAKIVDKELSKYPQTDILLGSMGLIVGFVIAYLL
                     SGLVNRIPIVGGILSLLLYLFLGYLGMKVALKSKNDLFNIGKLGRLANPIKDKDKDKE
                     NKKEVKAIPPKVLDTSVIIDGRIADICKTGFIEGKLIIPAFVLEELRHIADSSDDLKR
                     VRGRRGLDILNIIQKELNIEVEISERDFDDIAEVDSKLLKLAQVLNGKVVTNDYNLNK
                     VAQFQGVEVLNINELANAIKPVAIPGEDMVVQVVKEGKEAQQGVAYLDDGTMIVVDGG
                     RKYMNETIKVLVTSVLQTPAGRMIFAKPKN"
     gene            8643..10820
                     /locus_tag="PC512_001643"
     CDS             8643..10820
                     /locus_tag="PC512_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441389.1"
                     /translation="MRKKIISFLATFIIILTSASQYSFADDISTRGKVIFIDMNRTSM
                     SNMLRIKSLREELDNRGYIGLMNIRGDKGSDDRRSYASMGAGGRANVANEEDINFESS
                     SKDRNIVFESATGKSAKGINNLTINKSINENLNFGEYGSVLGSLGQSLSDNGLKASVL
                     GNSDIIENGQLIKNRNLCLTAMDEYGRIPNGNVDTINKKDLSMPYGISTDYDKLIVET
                     KETYKNNDVIFVELGDTYRLDLYKPNLNEKTYESMKDNIEKNIDIYLKNIFSMVEEND
                     TIYIASAFPSDLDYKNKRRLSPIIKLNGEGKGILSSSTTRREGIVTNLDVGVEILDNF
                     NIKNQNMVGRKYELINRDDNKEFLMDEYQKIVSISSIRSTILNGFVSIVFLSWIVAMI
                     AILFRKHISKNYKETTFFILKELLKIGIVMPLSFMITPIMNFKTPLAISLGIIIITLT
                     IYLISKVLIKNDLKNMLFFTGLTIVIMVIDAGFGSYLMKSNVMSYDCIIGARYYGVGN
                     EYQGVAIGSAIFTFAILLTYKNIPKWYIIVFSLVILITSASPIMGANVGSAISECVAF
                     LLFILLIYNVKIDFKKIVLLGIAVVFVLGVFVAIDMILGSNSHLGMFVKEIYFNGPGE
                     IIQTFSRKIEMNLKLAQTSAWVNILLTGIGVILVLMINQIRYFKQLMDEYPIVFKGFI
                     ASIAGCLVTLLVNDSGIVSSATAFIYVIVPMITLSINLTALKE"
     gene            complement(11006..11851)
                     /locus_tag="PC512_001644"
     CDS             complement(11006..11851)
                     /locus_tag="PC512_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2441390.1"
                     /translation="MNRNNFSHEIIEPIDNLDVNFKLFDDSGSYVANHWHNSLEIIYI
                     TSGDLQINMEGYTYNLKANECMFINSGIIHSTRCIYQNTSILLQVPLSFLNKYIPDFK
                     NCYFDFKVNANDNNYKKNSSKVKLILENMREIKLSSPPAANLLFTSLLFELLFELYTN
                     FKISVGNKNMKKTVLDLSKFEPVLEYTKINYKMPISINKIAKVAHLQPEYFCRKFKQY
                     MGQTYLEYLNDVRISHIYKDLINTNDTLCSILEAHGFTNTKLFYRIFKEKFKCTPKHI
                     RKKST"
     gene            12068..13234
                     /locus_tag="PC512_001645"
     CDS             12068..13234
                     /locus_tag="PC512_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulase family glycosylhydrolase"
                     /protein_id="HDF2441391.1"
                     /translation="MYIKGVNLGGWLVLEKWMTSSLFEGTEAEDEYYLPRQLSREAYE
                     SRIKTHRSEYITERDFATIKSMGFNSVRIPVPYFIFGDCEPFIGCVKELDKAFAWADK
                     YGLSILIDLHTVPGSQNGFDNGGISGICSWSQNPEYVAFTLNVLERLAKRYGMRHELY
                     GIQILNEPITERMWNIMNVPNRFKAVDKEMARGSKPNSLEFLRDFYIKAYRVMRPYMR
                     EENVIVFHDAFELKAWKDFMREEEFKNVVLDTHQYLMLAEADGCEQSIDSYLKYIREN
                     YAKDILQMQKYFPVICGEWSLFNSYVCGIDTNGGQSPLNGIESNIDKLSKDDKRELYR
                     KIAKAQLDAWRNGSGHYYWNYKLLLDTVNEEGWIGWDSWDLGKCVAQEWYPIEY"
     gene            13256..14902
                     /locus_tag="PC512_001646"
     CDS             13256..14902
                     /locus_tag="PC512_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HDF2441392.1"
                     /translation="MIKNPILPGFNPDPCICRKGDDYYLVVSSFEWFPGIPVYHSKDL
                     KNWELYTHILTDETKIDLKKLPSSKGIWAPCLTYCEEEDLFYIVYGIMNSMNARYFDV
                     DNYLITSKDIKGEWSEPVYLHSSGFDASIFHDDDGKKWIASLDWETREGYEKPGVICL
                     VEYCTKKKEIVGYPKRIWSGGTDRGCIEAPHITKRGDYYYIMCAEGGTGYGHSVTMGR
                     AKNIWGPYEKDSMNPIVTSIPGDFYERHDPDHLKPKYYNPESKLQKSGHGSYIETTSG
                     EVYLVHLTSRPFVPELRCTLGRETAIQKMKWTKDNWLRMEDESNLAKEYVSESKLEEH
                     LVSSIPSFDDFDSNELGLQYYAPRISPLSFADVKSRPGYVRIRGQESRTSLNKVSILA
                     RKLTSVYARITTKMEFYPEVHQHSAGLIMYYDNMNYINLRKYYSETLGQSALSIIHLE
                     NGEKTEFLNTRIPIKDIPIYLRLYIQGRKSYFEWSYDEKNYQRIGKVFDTTKFSDEYC
                     KYGEFTGTFIGLTCADRVKHKHYADFDFFEYIVDESKDVD"
     gene            14999..16372
                     /locus_tag="PC512_001647"
     CDS             14999..16372
                     /locus_tag="PC512_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2441393.1"
                     /translation="MNTEVNVKATTIRYEKISFFERISYGCGDLGCNIIYSAMSAFLL
                     FYYTNYADVSAAAVGSIMLVSRILDGFSDLTMGIIVDRTKSKYGKARPWILRMAIPFA
                     IAAVLLFSVPSNLGITSKLIYIFITYNLVSTVIYTAINVPYATLNSLITQNQYERGVL
                     SIFRMILATCGTLLINGLTLPLVEYFGNNLSAWTKTFFVFGIASIMVFFITFTGTKER
                     VKAVKQDRNEVIPFKIGIKSLFRNKYWIQITLCLVCIFIVFAINGGSSVYYAKFILGD
                     EKLFGPINMVSNISQIIAMFMVAPFIKKFGKRNVLIVGSIILISSNVMFIIVGQNHIG
                     VIFASAIKGIGSAGIASTMFAIVSDTIEYGEWKTGYRTEGLINSASSFGFKVGNGLGS
                     AILGAVLSIGGYVGTSATQSDLAIVSIKVCFIYLPIFITILQIIIMSFYKLDKEYSTI
                     LNELNTK"
     gene            16817..17770
                     /locus_tag="PC512_001648"
     CDS             16817..17770
                     /locus_tag="PC512_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HDF2441394.1"
                     /translation="MKKIGDLRLMMKCCSLYYEDNLNQQEIANQLGISRPTISRILKE
                     AFEQGIVKIQIVDVLKNDYQKIERSLERKYKLKEVIVVDDKQDALTQKQELARAVSEY
                     LTRVVKENDIIGVSIGTTLKEIPRYVEKSNCKNVTFIPLLGGIGDNEIDIHANQIAVS
                     LARAFGGDFKLLHAPAVMSDLSTKEKLCKDEKIKEVLDLIDKTTIAIVGIGNPMSLNS
                     TIMASGYMNEADIEDLKKYNSIGAICLQAFDKEGKTSILEFNQRVLGVKLEDLKKIKR
                     TIGVASGDEKIEAIKASLKAKFINSLAINHSLALKLLEDCD"
     gene            17808..18770
                     /locus_tag="PC512_001649"
     CDS             17808..18770
                     /locus_tag="PC512_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HDF2441395.1"
                     /translation="MSISKETLLEMYKRMNQARKFEEKVSWFFARGMVHGTTHLSVGQ
                     EASSVAAVMALEKGDLVSLTHRGHSQFIGMGIDLNKMMAELMGKETGFCKGKGGSMHI
                     ADIESGNLGANGVVGGGLTIAPGAALTQQYKKTGKIVLCSFGDGASNEGTFHEGINLS
                     SIWKLPIIFYCENNLYGMSTSIKRHMNIESIATRAASYGIEGISIDGYNPIEVYETVQ
                     KAAEKCRRGEGPVLIESRTYRWLGHSKSDANVYRTKEEIESWKAKDPIEFLKNYLIEN
                     NLSNEDELDKIQEFAKQSIEDAVEFAQNSPNPKIESLLEDVYAD"
     gene            18795..19781
                     /locus_tag="PC512_001650"
     CDS             18795..19781
                     /locus_tag="PC512_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HDF2441396.1"
                     /translation="MSTRELTYAQAIKEAMSEEMRRDENVIFMGEDIGIYGGAFGVSV
                     GMIDEFGPERVRDTPISEAAIAGAAAGAAATGLRPIMEVMFMDFVTISMDAIVNQAAK
                     MRYMFGGKAQVPMVVRCPGGSGTGSAEQHSQSLEAWFCHVPGVKVVAPSTPADAKGLL
                     KAAIRDNNPVIFVENKLLYRKKGFVPEDDYVIEIGKADIKREGTDVTVITYGRMLQSV
                     EEAAETLSKENINVEIIDLRTLYPLDKETIVKSVCKTGRVLICHEAAKTGGLGGEISA
                     LITESESFDYLDAPVKRICGKDVPIPYNPELEKAVVPRVDEIEEAIKSLIVR"
     gene            19794..20840
                     /locus_tag="PC512_001651"
     CDS             19794..20840
                     /locus_tag="PC512_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxo acid dehydrogenase subunit E2"
                     /protein_id="HDF2441397.1"
                     /translation="MVANKIKATPAARSQARKDNIKLDRLIGSGENGRIHLVDVLNYL
                     KDNKANTTPLARRIAEDLNIDLETIVGTGYNGKIRKCDVEKLTGKETIVSTNTSKSSE
                     KKELKIENENSRMFNTVEGIFEKPNPMRATVAKRMSESYFSAPVFTFNIEVDATELKV
                     LRAKLIDTVKESTGVKLTMTDLIVMAVSKILPNHQALNSAWTDEGIFRYKDVNIAIAV
                     GLDEGLYVPVVKNANKKSLKEIAKESKELAEKVKTGKLMPADQEGNTFTISNVGMYGI
                     TTFTPIINMPSSAILGVGATQDKFVPVNGEAKIKPIMNLSLTSDHRVIDGTVAAKFLK
                     DLKELLENPLSMLV"
     gene            21007..22737
                     /gene="lpdA"
                     /locus_tag="PC512_001652"
     CDS             21007..22737
                     /gene="lpdA"
                     /locus_tag="PC512_001652"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HDF2441398.1"
                     /translation="MSVEVIMPKAGVAMEEGTIVSWLKQEGEEVKIGEPILEITTDKV
                     NMEIESEGEGTLAVIIHKEEGEVLPVFTVIGVIAEKGENQEEVKAKYLSGNVSKEDIV
                     EENQNIEFKEEKINKKECNHDYDVVVIGGGPGGYLSALKAALLGGRVALVEENILGGT
                     CLNRGCIPTKTYIKTAEILEEIDQLSKRGVKVTVDKEQDIKKAIKYKNRVVKKLTAGV
                     GGLLKSRDVDVFNLKASVKEEHKVILSDGKVLDTENIIIATGSKVRILPIKGIESNLI
                     ITSTEALDLETVPEELVIIGGGVIGCEFAEIFNSRGSKVTIVEMEDRVIPRMDKELSE
                     SLKYSLSKKGINVLTKKKVSEFKEEGNNILVCIEGEEPIKADLCLYAIGREANLSGIE
                     DLDIKIDKGSIVVNSKMETSIPSIYAVGDVTGGVMLAHAAFKMGEVAASNALGVNKEV
                     DLGALPSCVYTIPEVASVGITEEDARKKYNVKVGKFNFAGNGRALASGQEQGYVKVVA
                     DAKYGEILGIHMFGCGVAELINHAASFKALEIPTDEASELIFGHPCTSEALMEALADV
                     NGECLHLPKK"
     gene            23155..26103
                     /locus_tag="PC512_001653"
     CDS             23155..26103
                     /locus_tag="PC512_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2441399.1"
                     /translation="MRQRIKNLIENEDKKNPLTDEAISSRLNIRREDVTFLRNELKIE
                     DSRQRRKVVLIKAIKDILKEEKTINKNDITRRLNSIGFTVSRFTVIQYLKEIQDSGDL
                     KLDKESDDKKEEIINNRENKDIAFDKLIGSSGSLSTIIKLAKAAILYPPHGLHTIIMG
                     PTGVGKSELAECMYKFAVESSRFPKNAPFIVFNAADYSENPQLLLSQLFGHVKGAFTG
                     ADENKEGLVSKADGGILFIDEIHRLPHEGQEILFQLIDKGMVRKLGETRLTHKIDVMI
                     ISATSEPIDSHLLNTFKRRIPVTIEIPELVARPLNERFDIINNFFLIEAQRMGANIHI
                     KSDVLKALMLYDCIGNVGQLRSDIQVACARGLLNQLTNKLKEVNISISDVPGYVKQGL
                     IKIRNCRGKIENYVDGDLIIDSNLQGEIEKKNEDIYTFPDEIYKLTERRHIDLLEQGL
                     DFDVINRIIGGELESCIQKYIKQVKKVSISNNLPDISPIVGKYIVELTYEVIKIASQY
                     LSSLEPNLHLCLAVHLKAAFERLKEGKVISNAHLKEIIGNYPVEYSVAEKVAQYLKER
                     YNINLPKEEIGIIAIYFKMSSRRDMSEQKKIGVLLMAHGRVASSVCEVTNKLLGINHA
                     RYLDMPFEKKPEEMIEEATTIIKDIDEGRGVIILVDMGSLSYFGDIISGKTGINIRTI
                     SRFDTLLSIEVIRRAVLPDLTIDEIVDEVKGIEPQVKEKVSKCNNTKVDFRKPIILTL
                     CITGLGGACKIKKILEENIKSITEKVDIEPIGMIEYPSLDLEIKQISNDKNVIAIVGT
                     IDPQIANIPFFSLVDINDKAKLNQINNLIDTNQIGETNKKYELSDLIHKEDIFVDLQV
                     KSKEEVLKYMSKKLREKGYVTKNFYKKVVERDNLFPTELSDEIAIPHTDGIDVIRPAI
                     SIAILKKPIVWSKSKVKIILLLAVDQKCFNPLSTLLSFIETDEFKKIKNIKDRDFIRE
                     MILDGVNENN"
     gene            26081..26545
                     /locus_tag="PC512_001654"
     CDS             26081..26545
                     /locus_tag="PC512_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2441400.1"
                     /translation="MESMKIISSNLIFKNIEVSNNEDALKFLGQRLFDEQYVKESYIQ
                     AVVAREKKYATGLPTEIYGVAIPHTDIVHVNEPGIAIGILNKPVKFIMMGTDDTEIDV
                     KVVFMLAVKEPQEQLQLLEKLMTIFQDKNILNNIVDLSEESVSDLLNSKLKN"
     gene            26658..26960
                     /locus_tag="PC512_001655"
     CDS             26658..26960
                     /locus_tag="PC512_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2441401.1"
                     /translation="MGVTNVAKKILVACGTGVCTSTIAINKLKKALQDIGKLDMVNIT
                     QCKVVEVASKAPDYDLIICTTQVSSSIKTPVINGLPFLTGVGMDKLINDVLEELEL"
     gene            27022..28386
                     /locus_tag="PC512_001656"
     CDS             27022..28386
                     /locus_tag="PC512_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425524.1"
                     /note="with GatAB forms a phosphoenolpyruvate-dependent
                     sugar phosphotransferase transporter for galactitol;
                     subunit IIC forms the translocation channel and contains
                     the substrate binding site; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HDF2441402.1"
                     /translation="MEGLYMEILNFIVGLGAQVMMPIIICIFGLILGTKLGKSLRAGL
                     TVGVGFIGLNTIIALLTDNLGPATQQMVKNLGLSLSIIDVGWPAASAIAFASTVGALI
                     IPIGLVVNIVMLITNTTQTVDVDIWDYWHFAFTGALVAGATQSVMWGVFASVANMVIV
                     LVMADLTAPGIEEYLGMPGISLPHGFTQAFVPIAIVVNKLLDLIPGINKIEINADTLQ
                     KKFGLFGEPLIMGSVIGVIIGIAAKYDIKGILQLGVTMGAVLILIPKMAALLMEGLLP
                     VSEAAQEFIEKRFKNRGKIYIGLDSAVGIGHPVTLSVALVLVPLTILIAAILPGNKVL
                     PFADLAVIPFALVLIVPITKGNVFRTLIIGIIIITSGLLIATNLAPLFTQMALNASFK
                     MPEGATMISSICDGANPLSWVFVKVMNYKVIGGVVFGVIALGMAIYNRNRIINENKKL
                     SIEE"
     gene            28421..28894
                     /locus_tag="PC512_001657"
     CDS             28421..28894
                     /locus_tag="PC512_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441403.1"
                     /translation="MKKYKYDSKRYLLSVTIPGFFMILILIYALFNNYTNFNLNIYSL
                     LIIVCTYGIFNTFISSSNPKKIIIDSKCIHFTSFMTTHKYEIKDIEKIRIREFYNKKI
                     YVKINDGNLFKGRYWIRTNMFNNSIALYSYFIELEECLYPDSLKFRNKKFENKNI"
     gene            29066..29716
                     /locus_tag="PC512_001658"
     CDS             29066..29716
                     /locus_tag="PC512_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HDF2441404.1"
                     /translation="MLLEKLRKEVLQASLDLLNYNLVTLTGGNVSGRDEQTGYIAITP
                     SGMDYRNLTPSDIVIVDVDGNIIDGKWKASVDLSDHLYIYKHREDINSIIHTHSTYSS
                     CFAILNEPIECASTTLANEVGGSVPVAKFSPPTSKKMGKCVIEAIGDKRACLLANHGV
                     IAVGPSVGHALTAAVMLEDSAKVYYLAKSIGTPVLLPDEEIQRARDVFFNVYGQDK"
     gene            29890..30822
                     /locus_tag="PC512_001659"
     CDS             29890..30822
                     /locus_tag="PC512_001659"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HDF2441405.1"
                     /translation="MYYLLNKSTNPYFNLALEEYLFLNDKYNDDIIIIWRNEESIFIG
                     KNQNPYQEVYHDVIEKGEIPILRRISGGGTVYHDLGNINMSFIQKDRQLHEIDFLEHT
                     KFMQKMLSTLGLDVSITERKDLFLNGKKISGSAQSIKRKNSLYHGTLLYDSDLNKLTK
                     YLNSNKATESNATKSVSSKVTNIKFLLEKDINYFLDYCVEYLKSNIKNIKELELDEED
                     IKSVYNIGEDKYKKIEWTYGKTPKFQVVLPFNNESKINIHVNRWKVSKFFISYDDNVI
                     NMDKLLDLNFFKEEIKESILENYPHYIDLINLIF"
     gene            31096..31809
                     /gene="ispD"
                     /locus_tag="PC512_001660"
     CDS             31096..31809
                     /gene="ispD"
                     /locus_tag="PC512_001660"
                     /EC_number="2.7.7.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HDF2441406.1"
                     /translation="MYSVIIVAAGSGRRMNLDINKQFIKLREKEIIAHTIQVFYENIN
                     IDEIVVCIKKEEEDFFKENIINKYNFKNIKIAYGGKERQDSIYNGLKKLDENCDIVLI
                     HDGARPFVDHRIINESIKVAKEKKAVVVGVPVSDTIKIVSDGTVQETPERNLLWAAQT
                     PQTFEYNLIIDAYEQAYKNNYYGTDDSMLVENIGQSVTMVMGSYENIKITSPEDLNIA
                     EQILNMEKRDEVNSRRRII"
     gene            31806..32291
                     /locus_tag="PC512_001661"
     CDS             31806..32291
                     /locus_tag="PC512_001661"
                     /EC_number="4.6.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 2,4-cyclodiphosphate
                     synthase"
                     /protein_id="HDF2441407.1"
                     /translation="MRIGLGYDVHKLTEDRKLIIGGVEIPHDKGLLGHSDADVLIHAI
                     MDSILGALALGDIGKHFPDTDEEYKGADSMKLLEHVYNLITSKGYKIGNIDSTIIAQS
                     PKMAPYIESMRSNISKVLNTDIDNINIKATTEEGLGFTGAKQGIASQSICLLLLTSQN
                     N"
     misc_binding    32386..32594
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            32658..34373
                     /locus_tag="PC512_001662"
     CDS             32658..34373
                     /locus_tag="PC512_001662"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HDF2441408.1"
                     /translation="MKMSKMFMPTLKEIPADAEITSHQLMVRSGMIKKMTSGVYNQLP
                     MGLRVFKKIEQIIREELNKKDCQEILCAALLPSELWKESGRWTAMGEEMFRLKDRTER
                     EYCLGPTHEEAFTDIIRQEITSYKQLPLNLYQIQVKYRDERRPRFGVMRTKTFTMKDA
                     YSFDVDDKGLDKSYQDMFDAYVSIFDRCGLENSPVQADSGAIGGSTSAEFMVKSEVGE
                     DEVVFCSGCDYAANVERAESCNLASQKEEMKELEEVHTPGAATIKELEEFLKTSPDKF
                     AKTLVYEADGKTVVVVVRGDREVNEIKVSNAIGSVIEFALATDDVVRKVTNAEVGFAG
                     PIGINADYVFIDKEIVEQRNIVVGANKTEYHIKNANYGRDFEGIVGDFRNVQEGDKCI
                     VCGKPLEIARGVEVGHIFKLGTKYSESMNANFIDKDGKSKPIVMGCYGIGVERTAAAI
                     IEQHNDEKGIIWPLSVAPYHVVIVPANMKNEEQISIAENIYNDLQAMGVEVLLDDRDE
                     RIGVKFNDSELIGIPMRITVGKNINEGKVEFKLRHKEDKEIIDIEEINEKVKAEFIRN
                     NVRLG"
     gene            34495..35940
                     /locus_tag="PC512_001663"
     CDS             34495..35940
                     /locus_tag="PC512_001663"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HDF2441409.1"
                     /translation="MAKNEKQFVEEITKMEDDFPQWYTDVITKTDLVDYAPVKGFMVV
                     KPYGYALWEKMQEFMDKKFKETGHKNCYFPLLIPESLLNKEAEHVEGFAPEVAWVTHG
                     GNKKLEERLCVRPTSETIICTMYAKWLKSYRELPYLYNQWCSVVRWEKSTRPFLRTSE
                     FLWQEGHTLHETAEEAQEETIQQLEVYKALCEELLAMPVVAGQKSESEKFAGGERTYT
                     IEAMMHDGKALQSGTSHFLGQHFTKAFDITFADREGNLANPYHTSWGASTRLIGGLIM
                     THSDNRGLVLPPRVAPIQVVIVPIAAKKGNVMETVDKIYADLKAKGVAVEVDDRDNYT
                     TGWKFNEWEMKGVPVRVEIGPKDIENNQAMVFRRDTLEKDSMPLEGLADAICDLFDVI
                     HNDMFEKARKHREDNTSIVENMDEFRKALEEKPGFIKTMWCGDAECEAKIKEETGATI
                     RCLPFEQENLGHKCVYCGKEADSMVVMAKAY"
     gene            36380..37861
                     /locus_tag="PC512_001664"
     CDS             36380..37861
                     /locus_tag="PC512_001664"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HDF2441410.1"
                     /translation="MNVRVRFAPSPTGFVHIGSLRTALYNYLFAKKMGGEYILRVEDT
                     DQSRLVEGAIENMLNAMKWAGVNHSEGVILDDSGKVVQKGEYGPYIQSQRLDIYQEYI
                     KQLLDSGKAYYCFCTKERLDEVRDAQRAAGETAKYDGHCKNLSKEEVEANIKAGIPYV
                     IRLRLPENHTIKFTDLVRGDMEFNTNDLDDQVLMKTDGFPTYHFAVVVDDYLMKITHV
                     IRGEEWVSSTPKHVYLYEAFGWEAPVFVHLPNILNKEKKKLSKRQGDVAVEDFKKKGY
                     LPEGLVNYVALVGWSPEDNQELFTMEELEKAFSVERVSKSGGVFDTEKLNWVNQHYIK
                     DGDDAYLTDLAIPFLIEDGFITEEEATNKYDFLKSMISVLKEKLQYVKEVTEHASIFF
                     GDKIEVETEEGREFLRLEHIPTLIDALREKIEKTEVLNAEFVQAMLKEIQKEYKIKGK
                     NLFMGSRIILTGQMHGPDLPKVMEVLGKETCLNRIAYVKNNIL"
     gene            38082..38237
                     /locus_tag="PC512_001665"
     CDS             38082..38237
                     /locus_tag="PC512_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441411.1"
                     /translation="MYSNIDDVKKELKELCLEYVTILEKLKDEKMITEETFEKCSSQK
                     KIFLEEQ"
     gene            38382..39779
                     /locus_tag="PC512_001666"
     CDS             38382..39779
                     /locus_tag="PC512_001666"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HDF2441412.1"
                     /translation="MKVYNTLTRTKEEFVPLEEGKVKMYVCGPTVYNYIHIGNARPFI
                     IFDTLRRYLEYRGYDVTYVQNFTDVDDKIINRSHEEGISPEEVAAKYIKEYFVDCDGL
                     GIKRATVHPQVTDNIQQIIEFIKELEDKGYAYAVNGDVYFDTNKFEGYGKLSGQKQED
                     LEAGARIEVNDQKRHPMDFVLWKAKKEGEPGWDSPWGEGRPGWHIECSVMSKRYLGET
                     IDIHAGGQDLTFPHHENEIAQSEARSGKTFSKYWMHNGYININDEKMSKSKGNFFTVR
                     DISKLYDLEIVRFFMLSAHYRNPVNFSDEMLNQAKAGLERLYNTKEKLEFTLSNLVES
                     PLTEKEVELVKELDDFRQKFIDAMDDDVNTADAVSVIFELAKLINSNVDENSSLEFAK
                     KCLDEFNELTGVLNIVNKKKDTVLDKDIEELIQKRTDAKKNKEFQLADDIRQQLLDMG
                     IVLEDTRQGVKWKRI"
     gene            39764..40177
                     /locus_tag="PC512_001667"
     CDS             39764..40177
                     /locus_tag="PC512_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HDF2441413.1"
                     /translation="MEKDIKMEKTELVTMSPLVLAYLGDTVYETYIREYLIRQNTQRK
                     VNDLHKLAIKYVKAKAQATIIHEIEIELTEEESKIYKRGRNQKSNTSPKNADIIDYKH
                     ATGFEALVGYLYLNNEIERLQYIINKGIKIIERDM"
     gene            40283..41041
                     /locus_tag="PC512_001668"
     CDS             40283..41041
                     /locus_tag="PC512_001668"
                     /EC_number="2.1.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent thymidylate synthase"
                     /protein_id="HDF2441414.1"
                     /translation="MKVKLISHTPEPEKVIAMAAKLCYSPVGTDEIEKDLTDESIEKF
                     LNMLLSIGHGSILEHASFTFSIEGISRACSHQIVRHRIASFSQQSQRYVKLEQFEYII
                     PPEIEKIEKAKELFIDSMKKDQENYDKLVEILFENHYNDLIKNGKNEKTAKRQAEKKA
                     IEDARYVFPNACETKMVFTINARSLFNFFEHRCCERAQWEIRNLAVEMLREVKKVAPI
                     LFKKTGPSCVNGSCPEGTMTCGDIVQVREKFKAL"
     gene            41054..41791
                     /gene="rlmB"
                     /locus_tag="PC512_001669"
     CDS             41054..41791
                     /gene="rlmB"
                     /locus_tag="PC512_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HDF2441415.1"
                     /translation="MASIEGRNPVIEAIKSDREIDKILIANSAKEGSIKKIIGMAKDK
                     NIIIQYVDKHKLDEVSTSHSHQGVIAYASEYKYYELDELIDLAKNKDEDPFFIILDEI
                     TDPHNLGSIIRTADAVGAHGVIIPKRRSVHITPVVAKASAGAVEYMPVCKVTNIVNTI
                     KRLKEEGLWIAAADMDGETFYKQNLTGPLGVVIGSEGFGISRLVKQNCDFIVKMPMIG
                     NVTSLNASVAGGILLYEIFRQRLDKSK"
     gene            41794..42321
                     /locus_tag="PC512_001670"
     CDS             41794..42321
                     /locus_tag="PC512_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HDF2441416.1"
                     /translation="MKKNINHYLIIDGYNIINAWDNLKELAKEDLEDSREKLIDDIIE
                     FSEFMGYKTIIVFDAYNVKNSREKVEKRKHITIVYTREHQTADSYIEKFITSLSKYDD
                     VKVATNDYAEQQMILGKGATRMSARELKLELDRSKNKMKEKNIGLRKKIQRNWLEERL
                     DKETLSKLENIRRKR"
     gene            42386..43033
                     /gene="sigH"
                     /locus_tag="PC512_001671"
     CDS             42386..43033
                     /gene="sigH"
                     /locus_tag="PC512_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigH"
                     /protein_id="HDF2441417.1"
                     /translation="MLVAKEKSYELVDNCQQDEYNIVLRASEGDKIALEYIITKYRNF
                     VKAKAKSYFLIGADKEDIIQEGMIGLYKAVRDFDGSKTNSFKCFAEICITRQIITAIK
                     TATRQKHIPLNSYVSLNKPIYDEESDRTLLDIIATSIVTDPEELIISKEELKNIESKM
                     NELLSDLELEVLELYLNGKSYQFIADKLKRDVKSIDNALQRVKRKLEKHLENRND"
     gene            43107..>43329
                     /gene="tuf"
                     /locus_tag="PC512_001672"
     CDS             43107..>43329
                     /gene="tuf"
                     /locus_tag="PC512_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887863.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HDF2441418.1"
                     /translation="MAKAKYERTKPHVNIGTIGHVDHGKTTLTAAITKTLYDRYQLGE
                     AVDFANIDKAPEERERGITISTAHVEYETP"
BASE COUNT        17761 a         4483 c         8124 g        12961 t
ORIGIN      
        1 aaatgtttag taataaagat gagaaggtat atttaaaata taaagtattt aaagttctga
       61 aatctaatca tgaagcaaaa aattagcatt tggttatcaa taaatataat aaataaaaac
      121 tcataattaa tgaaagaata aattcatgtc taaatttcta taaaaaattt aaatttatac
      181 aatttagggc tttaaaaatt taaataatag gtgtaaaata atagtcaaag aaagtcaaaa
      241 ataaaaaggt gtgtggtgat attaatggca actatgacag atataattga aaaatttatt
      301 aaagatttga tggaagaaga taatagcata caaattcaaa gaaatgaact agcaaacttg
      361 tttagttgtg caccatcaca aataaattat gtcttaacaa caagatttac aatagataga
      421 ggatattaca ttgaaagtaa aaaaggtggc ggaggatatg ttcaaataga aaaaatacga
      481 aaaagtaaag atgggcatat tagagaacta ctaaatgaaa aaataggaag tcagatatcc
      541 tataaaaaag caaaagaatt attagaaggt ttaaaagagt cggatttgat taacgaaaga
      601 gaattaaaat taatattata tgcaatagat gataaatcat tgtgtatgcc aatatatgaa
      661 ttaaaagaga aggtaaggtc taatatttta aagaatataa taataggatt atttagtata
      721 gaggagtgat aatttatgct atgtcaaaaa tgcaataaga ataaagcatc tgtatattat
      781 aataagatag tcaatggaga aaaaacagag atgtatttat gtagtgagtg tgcaaaagag
      841 aatacagaaa tgaattttaa cttagatatg cctttttcaa tgatggatat attttctaat
      901 ttaggttttc aacctaaaaa agaacttgag gaaaagctag tttgtcctaa atgcaataca
      961 acatatagtg agtttaagaa taatgggaga tttggatgta gtgaatgtta taatgcattt
     1021 agtagtcaag taaatccaat gcttcaaaat atacatgggc atatagaaca tacaggaaaa
     1081 gcacctaaaa aatcttttta taagataagt gtagaaaatg agattaaaga actaaaagaa
     1141 gatttagata gagctataaa aaatgaagag tatgaattag cagctcaatt tagagataaa
     1201 attaaatatt taaaaggttc tattgactaa gattggagtg atattatgaa agagaacata
     1261 gtcatgaaat caagagttag gctagctaga aatttaaata actatccatt tccaaataaa
     1321 ttagataaag aatgtgccat ggaaataata gaaaaagtaa aaaatgcgtt tattaattct
     1381 aacttagaac aaaaagaaga atttgatttc tataaaattg aagatttaga ccaatctaaa
     1441 aaaatgctta tggttgaaga acatataata agcccagatt tagcagaaaa tgataaaagt
     1501 gcagttatag taaaaaaaga taaaactata agtataatga taaatgaaga agaccatata
     1561 aggatacaaa ctatatgtga tgatttaaac ttagaatatg catatagtgt agcaaatgaa
     1621 atagatgatt tgttagaatc aagtttagaa tatgccttta acacaaagct aggttatcta
     1681 acatcttgtc caactaatac aggaacagga atgagagctt ctgtaatgat gcatttacca
     1741 gcattaagtc aactaggcta tatggatgaa ctttataaaa tttcatcaca aataggtata
     1801 gcaattagag ggatatatgg agaacgaaca gaagcattgg gaaatatata tcaaatatct
     1861 aatcaactta cacttggaag aacagagtct aatattatag aaaatgtaag tggacttaca
     1921 aaagatgcaa tttcaaaaga aataaaagct agagaaatat tgcaaaaaaa attaggtata
     1981 aaactagaag ataaaatatt tagatcgata gggacacttg aaaattcaag agtaatgagt
     2041 agcgcagagg caatgagcca tctatcaaat ataaaaatgg gaatagaaat gaactatata
     2101 gataaactag atttaagggc tatagaacaa cttatgatag gtatacaacc agcgcatcag
     2161 tcaataatgt ataagagtga tgatgttgag aatagagata taaatagagc aacatatatt
     2221 agagaaactt tggaaaaatt aagaggaggg atgaattgtg aacttcaata gatttacaca
     2281 aagagctaaa aaggcaattg atttagcgtt tgaatctgct aaaagtctag gacacaatat
     2341 tgtcggaagt gaacatatac ttttaggtct tttaagagaa gaagaaggta tagctgctaa
     2401 agttctaagt aaagttggat ttacagaagc ttatttagaa ggcaaaatag ttgatatgga
     2461 aggtaaggga gaagaaatct cagaagatat agtattaagt ccaagaagta aacaaatact
     2521 tgaattatca ggaatgtttg caaataaatt aaaaacaaat tatattggga ctgagcatat
     2581 attattagca attattcaag aaggtgaagg aatagctaat aagattttaa attatgctgg
     2641 agtaaatgat aggactttag cccaattaac aattgatatg atgggtatta gtgataaaaa
     2701 tcaatacaaa gcagaaaata gttacacggg caaccagaat caagcagaat ctaaagtact
     2761 tgataagtat ggaagaaatc ttacactata tgcaaaacag aataaaatag accctgtaat
     2821 aggtagagaa aaagaaatac aaagagtaat acaaatatta agtagaagaa ctaaaaacaa
     2881 tccagtgttg ataggagacc caggtgtagg gaaaacagcc atagctgaag gtctggctac
     2941 aaatatagcc ttaggaaatg ttccagaaac actaaaaaac aaaactttat actctttaga
     3001 gatgggttca ttattggctg gggctaagta tagaggagaa tttgaagaaa gaattaaaga
     3061 agttgtagat gaagttgtta aaaatggaaa cataatctta tttatagatg agatgcacac
     3121 aataataggg gctgggtcta ctggagaagg ctctatagat gcttcaaata tattaaagcc
     3181 agccttagca agaggagaaa tacaagttat aggtgcaact acaattgatg aatatagaaa
     3241 gcatgttgaa aaagattctg ctctagaaag aagattccaa ccagttatgg tagatgaacc
     3301 aactaaagag gactcaataa aaatattaga aggattaaga gataaatatg aagctcatca
     3361 taaagttaaa ataactgatg atgctataaa ggcagctgta gaattatcaa ctagatatat
     3421 atcagacaga tatctgccag ataaagctat agacttgatt gatgaagctg catcaaaagt
     3481 aagattaaaa gaaaatacac ctccttcaga aataaaaaaa ttagaactag aaatagaaaa
     3541 tatagataaa gaaaaagaag aagcagtaag atgtcaagac tttgagaaag cagccaaaat
     3601 aagagatgaa caaggtctac ttaaaaaaca attagaagat gttagagaaa gatggaacaa
     3661 gtcatctaaa cattcagatt tagttgatgg agaagttatt gctgaagtag tgggcttatg
     3721 gacaggaata ccagttaata aaattcttga agaagaggct gatagacttt tgagacttga
     3781 ggaaatactg cacaatagag ttataggtca agaacaagca gtaaaatcta tttcaaaggc
     3841 aatcagaagg tcaagagcag gtcttaaaga ccctaataga ccaattggtt catttttatt
     3901 tttaggtcca acaggagtag gtaaaacaga attatctaag gcattagcag aagtgcaatt
     3961 tggagatgaa aatcaaataa ttagaataga tatgtctgaa tatatggaaa aacatgctgt
     4021 gtcaagaatg ataggttcac ctccaggtta tgtaggtcat gatgaaggtg gtcaattaac
     4081 tgaaaaagta agaagaaatc catattcagt tatattattt gatgagatag aaaaagctca
     4141 tccagatgta tttaatattc tgttacaaat tctagatgat ggtagactaa ctgattcaaa
     4201 aggaagaact gtagatttta agaatactat tgtaataatg acatcaaatg ttggagcatc
     4261 tacaattggt agacaaaaaa ctttaggatt tagtatagct aaaggagacg aagaagaaaa
     4321 atctcaatat gaaaaaatga aagaaaatat aatgggtgaa ttaaaacaaa gattcagacc
     4381 agagttttta aacagaatag atgatataat tgttttccac tcactaaatg aaaatcatat
     4441 atcaaaaata gtacttttaa tggcagcgaa actacaagag agattaaaag aaatggatat
     4501 aaaattagaa atgagtgatg aggctgttaa attaatttct aaatctggat ttgacttaga
     4561 atatggagca agacctctta aaagagcttt acaaaaagag ttggaagatg agctatctga
     4621 agcaatctta aaaggtaatg tgaaaaaggg aagtaatgta gtagcaaaag tcaaagatga
     4681 aaaaatagtt tttgaaacta aataatttaa tagagttgca ttttaaaata ttgcaaatat
     4741 aagttttata atctaaacaa aattttaagg gcaatgaatc tataataatt cattgtcctt
     4801 aattatttta tttaatcttt acatattgtc tttcagatat gctaaaatta tagtatagaa
     4861 taaaaaatta aggatgataa aagtatggca aaaataaaaa caaaatatgt atgtcaatct
     4921 tgcggatatg aaacagctaa atggcttggt aaatgtccag aatgtacaaa atggaataca
     4981 tttgtagaag aaatagacca aaaaagcacc aaaaaagagg tctttataat agataaatct
     5041 tcatctaaac cagtcagtat aaactcaata gaaagtaaag aagaagagcg gtttacaaca
     5101 gatataaatg agttagatag agtgcttgga ggaggtatag ttaaaggctc tttagtgctt
     5161 gttggtggtg accctggtat aggtaaatca acacttttaa tccaagtatc tagtaatgtt
     5221 gccaatttag gaaaaactgt tttatatata actggagaag aatcagaatc tcaaataaaa
     5281 atgagagcta aaagattagg tattaactca gaaaatttat atatatttgc tgaaaataat
     5341 ttaagtataa ttgaatctta tttagaaagt gtaaatccag aattaataat tctagactca
     5401 attcaaactg tcttcagtcc agaaatatcc tcggcaccag gaactgtcag ccaaattaaa
     5461 gaaggtactt caaaattcat gaaaatttct aaaaaaatgg gaatttcaac gttcatagtt
     5521 gggcatgtta caaaagaagg ttcactagca ggaccaaaat tattagagca tatggttgat
     5581 actgttctat attttgaagg agaaagatat aatacttata gattagtaag agctgttaaa
     5641 aatcgatttg gttcaactaa tgaacttgga gtatttgaaa tgagggattt aggattagta
     5701 gaacttgata atccatctaa aattttaatc tctgaaaaac caaaagatgt agcaggttca
     5761 gtaataatat ctactgtaga aggtacgaga ccaatgttac ttgaattgca agcattagtt
     5821 tctcctacaa gttttggtat accaaaaaga acatctacag gagtcgatta caatagagta
     5881 ggtatgttat tagcagtatt agaaaaacgt gttggtttgc aaatacaaaa tcaagatgtc
     5941 tatataaaca tagttggagg aataaagata aatgaaccct caattgattt agggatagcc
     6001 atttctgtag catctagttt tagaaatata ccgatagatg aagatatagc tgttacagga
     6061 gaagtgggac ttacaggaga agttagagca gtaagcttta tagaaaagag aatagctgag
     6121 tgtaaaaaac ttggatttaa aaagatagta gttcctagaa gtaattatga tgttgtaaaa
     6181 gagaccaaag gcatagaaat atggccagta gataacttaa gacaagctat aaatatagta
     6241 cttgggagga atcaataaat atggagaatt ttctagataa taaaaatatg ctatatgcat
     6301 taaaaatgat atctcctgga actccactta gattaggtct aaacaatgta ctaagagcta
     6361 agactggtgg attaattgta attgcaacaa acgaagatgt aatgaaaata gtagatggag
     6421 gatttgctat aaatgcagaa tattcaccat catatctata tgaattagct aaaatggatg
     6481 gagctatagt tttaagtggt gatgtaaaga aaatattatt tgctaatgca caacttatac
     6541 ctgactattt tatagaaaca tcagagacag gaacaagaca tagaacagca gaaagagtag
     6601 caaaacaaac tggtgctata gtcataggaa tttcacaaag aagaaatgtt ataacagttt
     6661 atagaggaaa tgagaagtat gtagtcgaag atatatctaa gatatttact aaggcaaatc
     6721 aggctataca aactctggaa aaatataaga cagtattgga ccaagctgta acaaatttaa
     6781 atgccttaga gtttaatgat ttggtaacta tttatgatgt tgcattagtc atgcaaaaga
     6841 tggaaatggt aatgagagtt acaagtataa ttgaaaaata tgtgatagaa ttgggtgatg
     6901 aaggaacttt agtaagtatg caattagaag aattaatggg tacaaccaga atagaccaga
     6961 aattaatatt caaagattat aataaagaaa acacagaaat aaaagaactt atgaaaaagg
     7021 tcaaaaattt aaattcagaa gaactaatag aattggtcaa tatggcaaaa ctattagggt
     7081 atagtggttt ttcagaaagt atggatatgc ctataaaaac aagaggttat aggattctta
     7141 gcaaaataca tagactacca acagcaataa tagaaaactt agtaaattat tttgaaaact
     7201 ttcaacaaat tttagatgca tctattgaag aattagatga ggttgaagga ataggtgaaa
     7261 taagagcaac atatataaaa aatggactca taaaaatgaa acaattagtc ttattagata
     7321 gacacatatg atgaatttta aatgaatttt actacttttt tcttgaatat aatatacact
     7381 ttggtctata atagataagt ataactaggg ggtgaagcat tgataaggaa agtaacaaga
     7441 atattgttta ttttacttgg atttacaata ggtataacaa cctatttaac attaatgaaa
     7501 gattttgaaa tattaacatt tggaaaagaa acatatggtt atatcgcagc tgtagtagca
     7561 ggtataataa tagccatttt aggatatctt atagaaccat gggttgtaaa taaagtaaaa
     7621 gaaattgcta aaatagtgga taaagaattg tcaaaatatc ctcagactga tatattgtta
     7681 gggtctatgg gtcttatagt aggatttgtt attgcgtatt tattaagtgg attagtaaat
     7741 agaataccaa tagtaggtgg aatactatcc ttactattat atttattcct aggatatctt
     7801 ggaatgaaag ttgcgcttaa aagtaaaaat gatttattta atattggaaa actaggaaga
     7861 ttagcaaatc ctattaagga taaagataag gataaagaaa ataaaaaaga agtaaaagcc
     7921 attcctccaa aagtattaga tacaagtgta ataattgatg gaagaatagc tgatatttgt
     7981 aagactgggt ttatagaagg aaaacttatt attcctgctt ttgttttgga ggaactaaga
     8041 catattgcag attcttcaga tgatttaaaa agagtaagag gtagaagagg tctggatata
     8101 ttaaatataa ttcagaaaga attaaatata gaagttgaaa taagtgagag agactttgat
     8161 gatatagcag aagttgatag taaattatta aagcttgctc aggttttaaa tggaaaagtt
     8221 gttacaaatg attataactt aaataaagtt gctcaattcc aaggtgttga agtattaaat
     8281 ataaatgagt tagctaatgc tataaaacca gttgctatac caggtgaaga tatggttgtt
     8341 caagtggtta aagaaggaaa agaggctcaa caaggtgttg catatctaga tgatggaact
     8401 atgatagttg ttgatggagg aagaaaatat atgaatgaga ctataaaagt actcgttact
     8461 tctgttcttc aaactcctgc aggtagaatg atatttgcaa aacctaaaaa ttaatatgtt
     8521 caaagaaacc tataatttgg gctgtttatt ttaaatagat ggtccaaatt tatttattta
     8581 taacgataat gtttaatgta ttcttaaaga tggggattta aatcagaaag cagggagaat
     8641 ttatgagaaa aaagattata tctttcttag caacatttat cataatatta acatcagcaa
     8701 gtcagtatag ttttgcagat gatatatcaa cacgtggaaa agtaatattt atagatatga
     8761 atagaactag tatgagtaat atgttaagaa taaaatcatt aagagaagaa ctagacaata
     8821 gagggtatat tggcttgatg aatataagag gcgataaagg aagtgatgat agaaggtcat
     8881 atgctagtat gggtgctggt ggtagagcta atgtggctaa tgaagaagat attaattttg
     8941 aaagctcgag taaggataga aatatagttt ttgaatcagc tacaggaaaa agtgcaaaag
     9001 gtataaataa tttaactata aataagtcta taaatgaaaa tttaaacttt ggagagtatg
     9061 gttctgtatt agggtcatta ggacaaagtt tatctgataa tggattaaaa gcatctgtat
     9121 tgggtaattc agatataatt gaaaatggtc aacttataaa aaatagaaac ttatgtctaa
     9181 ctgcaatgga tgaatatgga agaataccta atggaaatgt agatactata aataaaaaag
     9241 acttatctat gccttatgga atatcaactg attatgataa attgattgta gagactaaag
     9301 aaacttacaa aaataatgat gtgatttttg tggagcttgg agacacatat agattagatt
     9361 tatataaacc aaatttaaat gaaaaaacat atgagagtat gaaagataac atagaaaaaa
     9421 atatagatat atatttaaaa aatatatttt ctatggttga agaaaatgac actatctaca
     9481 tagcaagtgc atttccaagt gatttagatt ataaaaataa aagaagactt tctccaataa
     9541 taaaattaaa tggagaaggg aaaggtatat tatcatcttc aactactaga agagaaggta
     9601 ttgtaacaaa tttagatgtt ggggttgaaa tattagacaa ctttaatata aaaaatcaaa
     9661 atatggttgg aagaaaatat gaacttatta acagagatga taataaagaa tttttgatgg
     9721 atgaatatca aaagatagta tctatttcaa gcataaggtc tacaatactg aatggttttg
     9781 taagtatagt tttcttgtca tggatagttg ctatgattgc aattttattt agaaagcata
     9841 tatcaaaaaa ttataaagaa acaacatttt ttatattaaa ggaactttta aaaataggaa
     9901 tagtaatgcc actgtcattt atgataacac caataatgaa tttcaaaaca ccattagcaa
     9961 tatctttagg aataattata ataacactta ctatatatct tataagtaaa gttttaataa
    10021 agaacgattt aaaaaacatg ctgtttttta ctggattaac catagtaatt atggttattg
    10081 atgctgggtt tggctcatat ttaatgaaaa gcaatgttat gagttatgat tgtataattg
    10141 gagctagata ttatggagta ggaaatgagt atcaaggtgt ggcaatcggt agtgcaatat
    10201 ttacatttgc aattttactt acatataaaa atataccaaa gtggtatata atagtttttt
    10261 ctttggttat cttaattaca agtgcatctc caattatggg agcaaatgtt ggaagtgcta
    10321 tttctgaatg tgttgcattt ttactattta tactattgat atataatgta aagatagatt
    10381 tcaaaaaaat cgtattatta ggtatagcag tagtatttgt attaggagtt tttgtagcaa
    10441 tagatatgat tttgggaagt aattcacatt taggtatgtt tgtaaaagaa atttacttta
    10501 atggaccagg agaaataata caaacattta gtagaaagat agagatgaat ttaaagctag
    10561 ctcaaaccag tgcatgggta aatatactgt taactggaat aggtgtaatt ttagttctta
    10621 tgattaatca gattagatac tttaagcaac tgatggatga gtatccaatt gtatttaaag
    10681 gatttatagc atcaatagca ggatgtttag taactctttt agtgaatgac tctgggattg
    10741 tgtcatcagc tacagccttt atttatgtaa ttgtacctat gataacatta agtataaatc
    10801 ttacagcatt aaaagaataa gtactgtatg aataatatgt aaatattaat acattaattt
    10861 aacttcttta tttacaaaat aaagaagaaa gtttataaaa aataaattat aataaaaaag
    10921 agtttatctc aaaattgatt attctaatca aattttaaga taaacttttt ttattataaa
    10981 gataaataac atataacctc atattttagg tagatttttt tcttatatgt ttaggagtgc
    11041 atttaaattt ttccttaaaa attctgtaaa ataattttgt attagtaaat ccatgagctt
    11101 ctaatatact gcataaggta tcatttgtgt taattaaatc tttataaata tgagaaatac
    11161 gcacatcatt taaatactct aagtaagttt gtcccatata ctgtttaaat tttctacaaa
    11221 aatattctgg ttgtaagtgt gctaccttag cgattttgtt aatagaaata ggcattttgt
    11281 aattaatctt tgtatattct aaaactggtt caaattttga caaatcaagt actgtttttt
    11341 tcatattttt attacctaca gatattttaa agtttgtata taattcaaat aaaagttcaa
    11401 ataataagct tgtaaagagc agattagctg caggaggaga actaagttta atttctctca
    11461 tgttttctaa tataagttta actttacttg aatttttttt atagttattg tcattggcat
    11521 taaccttaaa gtcaaaatag caatttttaa aatcagggat atatttgttt agaaaagaca
    11581 atggtacttg caataatata gaggtatttt gataaataca tctagttgag tgaataattc
    11641 cagaattaat gaacatacac tcattagctt ttaaattata agtgtaaccc tccatgttaa
    11701 tttgtaaatc accagaagtt atataaatta tttctaatga gttatgccaa tgatttgcta
    11761 cataactacc actatcatca aatagtttga aattaacatc taaattatca ataggttcaa
    11821 ttatttcatg tgaaaaatta tttctgttca taataatatc ctccttataa ttttaaatta
    11881 taaatagtaa atttataatg ttcaatatta aaaagataat atagactaat aaattagata
    11941 ataaacatac ttaagaaaac ggataaaatc aaatataata actgtatatt aaaataactt
    12001 aaaaaaatta ttttattata agtgcaaaat atacctattt aaataagata agaggggagg
    12061 attttatgtg tatataaaag gtgtaaattt aggaggttgg ttagttttag aaaaatggat
    12121 gacctcaagt ttatttgaag gcacagaagc tgaagatgaa tactatttac caagacagct
    12181 ttcaagagag gcatatgaat ctagaattaa gactcatcgt agtgaataca tcacagagag
    12241 agattttgca acgattaaat ctatgggatt taattcagtt cgtataccag taccatactt
    12301 tatttttgga gattgtgaac cattcatagg atgtgttaaa gaacttgata aagcatttgc
    12361 ttgggcagat aagtatgggc ttagtatatt gatagactta catacagttc caggaagcca
    12421 aaatggattt gataatggag gaatatcagg tatatgtagc tggtcacaaa atccagaata
    12481 tgtagcgttt acattaaatg tattagaaag acttgcaaaa cgttatggga tgaggcatga
    12541 attgtatgga atccaaattt taaatgagcc tataacagaa agaatgtgga acataatgaa
    12601 tgttccaaat cggtttaagg ctgtagataa ggagatggca agggggagta aacctaattc
    12661 attagagttt ttacgtgatt tttatataaa agcatatagg gtaatgcgtc cttatatgag
    12721 agaggaaaac gttatagtgt ttcatgatgc atttgaatta aaagcatgga aagactttat
    12781 gagagaggaa gaatttaaaa atgttgttct agatacacac caatatttga tgttagctga
    12841 agcagatgga tgtgaacaaa gtattgatag ctatctcaaa tatattagag aaaattatgc
    12901 taaagatatt ttacaaatgc aaaaatattt tcctgttata tgtggggagt ggagcttatt
    12961 taattcatat gtttgtggta tagatacaaa tggaggtcaa tcacctctaa atgggattga
    13021 atcaaatata gataaattat caaaagacga taaaagagaa ttatatagga agatagcaaa
    13081 agcacagctt gatgcatgga gaaatggaag tggtcactac tattggaatt ataagttatt
    13141 actagataca gttaatgaag aaggttggat aggatgggat agttgggacc taggcaaatg
    13201 tgtagctcaa gaatggtatc ctatagaata ttaaactaaa attggaggaa aagatatgat
    13261 taaaaaccct atacttccag gttttaatcc agatccttgt atttgtagaa agggagatga
    13321 ttattatctt gtagtttcat cttttgaatg gtttccaggt atacctgttt atcactctaa
    13381 agacttaaaa aattgggagt tatatactca tattttgaca gatgaaacaa aaatagattt
    13441 gaagaagctt ccttcatcta aaggaatttg ggcaccctgt ttgacttatt gtgaagaaga
    13501 agatttattt tacatagttt atggaattat gaactctatg aatgcaagat attttgatgt
    13561 tgataattat ttaattacat caaaagatat aaagggagag tggagtgaac cagtatatct
    13621 acactcatca ggttttgatg cgtctatttt tcatgatgat gatggtaaaa agtggattgc
    13681 atcattagac tgggagacta gagaaggata tgaaaaacct ggtgttatat gtttagtgga
    13741 atactgtaca aaaaagaaag aaatagtagg atatccaaag agaatatggt cagggggaac
    13801 tgatagaggt tgtattgaag caccacatat aacaaagcgt ggagattact attatataat
    13861 gtgtgcagaa ggtggaactg gatatggtca tagtgtaact atgggaaggg ctaaaaatat
    13921 atggggacct tatgaaaaag attcaatgaa tccaattgta acttcaattc caggcgattt
    13981 ttatgaaaga catgaccctg accatctaaa gcctaaatac tataatccag aatcaaaact
    14041 tcaaaaatct ggtcatggaa gctatataga aacaacatca ggtgaagtat atttagttca
    14101 tctaacatct agaccatttg taccagagtt aaggtgtact ttaggtagag aaacagctat
    14161 tcaaaaaatg aaatggacaa aggataattg gcttcgaatg gaagatgaaa gtaatttggc
    14221 aaaagaatac gtatcagaaa gtaaactaga agaacattta gtttcatcta taccaagttt
    14281 tgatgacttt gattcaaatg aattaggttt acagtactat gctcctagga tttcaccatt
    14341 atcatttgca gatgttaagt ctagaccagg atatgtaagg attagaggac aagaatcaag
    14401 aacatcatta aataaagtaa gcatattggc aagaaaatta acttcagtat atgcaagaat
    14461 aaccactaag atggagtttt acccagaggt acatcagcat agtgcgggtt tgataatgta
    14521 ttatgataat atgaattata taaatttaag aaagtattat agtgaaacat tgggtcaaag
    14581 tgcactatca ataatacatc ttgaaaatgg agagaaaacg gaatttttaa atactaggat
    14641 accaataaaa gatataccaa tatatcttcg tctgtatata caaggtcgta agtcatattt
    14701 tgaatggagt tatgatgaaa aaaactacca gagaatagga aaggtatttg atacaactaa
    14761 gttttcagat gagtactgta aatatggaga atttacaggt acgtttatag gattaacttg
    14821 tgcagatcgt gtaaagcata aacactatgc tgattttgat ttttttgaat atatagtaga
    14881 tgaatcaaaa gatgtcgatt aataaaatca ttactaaaat tttcagagca aaggtaaatc
    14941 ttatgctctg aaataagaaa cattagaagg caaatcttac aaaaaggagt atggtattat
    15001 gaatacagaa gttaatgtta aagcaactac gattagatat gaaaagattt cattttttga
    15061 aagaatttct tatggttgtg gggatttggg gtgcaatatc atatactcag ctatgtcagc
    15121 atttttgctg ttttattata ctaattatgc agatgttagt gcagcagctg taggtagtat
    15181 tatgcttgta tctaggatac tggatgggtt tagtgactta acaatgggaa ttatagtgga
    15241 tagaactaaa tccaaatacg gtaaggctag gccttggatt ttgagaatgg cgattccttt
    15301 tgctatagca gcagtattat tattttctgt tccatcaaat cttggtatca cttctaaatt
    15361 aatttatatt tttattacat ataacttagt ttctactgtt atttatacag caatcaatgt
    15421 accctatgca actctaaatt cacttataac tcaaaaccag tatgaaagag gagtattaag
    15481 tatatttaga atgatattag ccacttgtgg taccttacta ataaatggac ttacactacc
    15541 tctagttgaa tactttggaa ataatttatc agcatggact aaaacattct ttgtatttgg
    15601 aatagcatct ataatggtat tttttataac atttactgga accaaggaaa gagtaaaagc
    15661 agttaagcaa gataggaatg aagtaatacc atttaaaata ggtattaaat ctttatttag
    15721 aaataagtac tggatacaaa taacattatg tttagtttgc atatttattg tatttgcgat
    15781 aaatggtggt tcatccgtat attatgcaaa gtttattttg ggagatgaaa aattatttgg
    15841 tcctataaat atggtttcaa atatatccca aattatagct atgtttatgg ttgctccttt
    15901 tataaaaaaa tttggaaaaa gaaatgtatt aatagtaggt tcaataatat taatatcgtc
    15961 aaatgttatg tttataatag ttggacaaaa tcatatagga gtaatatttg caagtgctat
    16021 aaagggaata ggaagtgctg gaatagcatc aacaatgttt gctattgttt cagatactat
    16081 tgaatatgga gaatggaaga ctggatatag aactgagggg cttataaata gtgcatctag
    16141 ttttgggttt aaagtgggaa atggattagg ttcagcaata ttaggtgcag tattatcaat
    16201 tggtggttat gtaggaacat cagctactca aagtgattta gctatagtat caataaaagt
    16261 atgttttata tacctaccta tatttataac aatattacaa attatcataa tgtcttttta
    16321 taagcttgat aaagaatata gtactatact taatgaatta aatactaaat aatgaaaaag
    16381 tttcttataa agtcttaagt ttaattaagg tctattgtaa atgttcccta taaaaactat
    16441 tatatattta tgattattga agaattttta gagaagcgaa taataaaaat ataagaagac
    16501 tttaaatgat gaaatggttg gttttttaga aatgatttaa taagttattg ttatttaaag
    16561 cattataagt ggacaattaa tttttaattt atggagatga tatttaacaa ttagaagtaa
    16621 tatataatat gcactaagaa gcaatttttc aactatttat gaaggtggtg gtacaagaaa
    16681 agtatcacct tttttttgtt atacaaaaaa acagttgact ttttatatga accccttcta
    16741 taatgttact gaaattaagt aaaatgattg aacaaatgta aagataattg aaaagcttga
    16801 ttttggagga aagcaaatga aaaaaattgg agacttaaga ttaatgatga agtgttgttc
    16861 actttattac gaagataatt tgaatcaaca ggaaatagca aatcaattgg gaatatcaag
    16921 accaacaata tcaagaatat taaaagaagc ttttgaacaa ggaatagtaa aaatacagat
    16981 agttgatgtt ttgaaaaatg attaccaaaa aatagagaga agtttggaga gaaaatataa
    17041 attaaaagaa gtaatagtag tagatgataa acaggatgca ctaacacaaa aacaagaact
    17101 agcaagagct gtatctgaat atttaactag agtagtaaag gaaaatgata taataggtgt
    17161 ttcaatagga acaacactaa aagaaatacc aagatatgtg gaaaaaagta actgtaaaaa
    17221 tgttacattt atacctctat taggagggat tggagacaat gaaatagata ttcatgcaaa
    17281 tcaaatagcc gtaagtttag cgagggcttt tggaggtgat tttaaattat tacatgctcc
    17341 agctgttatg tctgacttgt ctacaaaaga gaaactttgc aaagacgaaa aaattaaaga
    17401 agtactagat ttaatagata aaacaactat agcaattgtg ggtataggaa atcctatgag
    17461 tttaaactca acaataatgg cttctggata catgaatgaa gcagatatag aagatttaaa
    17521 aaaatacaac tcaataggtg caatttgttt acaagccttt gataaagaag gaaaaacttc
    17581 tatacttgaa tttaatcaaa gagtattagg agtgaaactg gaagatttaa aaaagataaa
    17641 aagaacaata ggtgtcgctt caggagatga aaaaatagag gcaataaagg catcattaaa
    17701 agcgaaattt ataaatagtt tagcaattaa tcacagttta gcacttaaat tattagaaga
    17761 ttgtgactaa tagaaagata gataaaagtt aacaggaggg aatgtatatg tcaatatcaa
    17821 aagaaacatt gcttgaaatg tataagagaa tgaatcaggc tagaaaattt gaagagaaag
    17881 ttagttggtt ttttgcaaga ggtatggttc atggaacaac tcacttatct gtaggtcaag
    17941 aagcgtcaag tgtggcggct gtaatggctt tagaaaaagg agatttagta tcattaactc
    18001 atagaggaca tagtcaattt ataggaatgg gaatagacct aaataaaatg atggctgaac
    18061 ttatgggtaa agaaactgga ttttgtaagg gaaaaggagg ctcaatgcat atagcagata
    18121 ttgagtcagg taacttagga gcaaatggag ttgtaggtgg aggtcttaca atagctccag
    18181 gagctgcact tacacaacag tataaaaaaa caggcaaaat agttttatgt agttttggtg
    18241 atggagcatc aaatgaaggt acttttcatg aaggaataaa tttatcttca atatggaaat
    18301 tgccaataat attttactgt gagaataatt tatacggtat gtcaacaagc ataaaacgtc
    18361 atatgaatat agaaagtatt gccactagag cagcttctta tggaatagaa ggaatatcaa
    18421 tagatggata taacccaata gaagtatacg aaacagtaca aaaagctgct gagaagtgta
    18481 gaagaggaga aggacctgta ttaattgaaa gtagaactta tagatggtta ggtcattcaa
    18541 aatcagatgc aaatgtatat agaacaaaag aagaaataga atcatggaaa gcaaaagacc
    18601 ctattgaatt tttaaaaaat tatcttatag aaaataatct atctaatgaa gatgaattag
    18661 ataagattca agaatttgca aagcaatcaa tagaagatgc agtagagttt gctcaaaata
    18721 gcccaaatcc aaaaatagag tctttattag aggatgtata tgcagactaa gaatggtaaa
    18781 ggaggaaaat aaaaatgagt acaagggaat taacatatgc acaagcaata aaggaagcaa
    18841 tgtcagaaga aatgagaaga gatgaaaatg taatatttat gggagaagat ataggaatat
    18901 atggaggagc atttggtgta tcagttggta tgatagatga atttggacca gaaagagtaa
    18961 gggatactcc tatatcagaa gcagctatag caggagcggc agcaggtgca gcagcaactg
    19021 gcttaagacc tattatggaa gtaatgttta tggactttgt aacaatttct atggatgcaa
    19081 ttgtaaatca agcggcaaaa atgagatata tgtttggagg aaaagcacaa gttccaatgg
    19141 ttgttagatg cccaggaggt tctggaactg gttcagcaga gcaacattca caaagtttag
    19201 aagcttggtt ttgtcatgta ccaggagtaa aagtagttgc accttctaca ccagcagatg
    19261 ctaagggatt gttgaaagca gctataagag ataataatcc agtcatattt gttgagaata
    19321 aattgttata cagaaaaaaa ggttttgtgc cagaagatga ttatgtaatt gaaattggaa
    19381 aggcagatat taaaagagag ggtactgatg ttacagtaat tacttatgga agaatgttac
    19441 aaagtgttga agaagcagca gagactctat caaaagaaaa tataaatgtt gaaattatag
    19501 atttaagaac tttatatcca ttagataaag agactatagt aaagagtgta tgtaaaactg
    19561 ggagagtttt aatttgccat gaagcagcta agactggtgg gctaggtgga gaaatatcag
    19621 ccctgataac agaaagtgaa tcatttgatt atttagatgc tccagtaaaa agaatttgtg
    19681 gaaaagatgt gccaatacca tataatccag agttagaaaa agcagttgtc ccaagagttg
    19741 atgaaataga agaagcaata aaatctttaa ttgttagata aggagggata gatatggtgg
    19801 caaataaaat aaaagccaca ccagcagcta gaagtcaggc aagaaaagac aatataaaat
    19861 tagataggct gattggaagt ggagaaaatg gaaggattca tttagtagat gtgttaaatt
    19921 atttaaaaga taataaagca aatactactc ctttagctag aagaatagca gaagatttaa
    19981 atatagattt agaaactatt gtaggtactg gatataatgg aaagataaga aagtgtgatg
    20041 tggaaaaatt aactggaaaa gaaactattg tatcaactaa tacatctaaa tctagtgaga
    20101 aaaaagagct gaaaattgaa aatgaaaatt caagaatgtt taacacagta gaaggaatat
    20161 ttgaaaagcc aaatccaatg agagctactg tagcaaaacg aatgtcagaa agttatttta
    20221 gtgctcctgt atttacattc aatatagaag tagatgctac agaattgaag gtacttagag
    20281 caaagttaat cgacacagta aaagaatcaa ctggagtaaa attaactatg acagatttaa
    20341 tagtaatggc agtatctaaa atacttccaa atcatcaagc cttaaattca gcatggacag
    20401 atgagggtat atttagatat aaagatgtaa atatagctat tgcagttggt ttagatgaag
    20461 gcttatatgt tccggtagta aaaaatgcaa acaaaaagtc tttaaaagaa atagcaaaag
    20521 aaagcaaaga acttgcggaa aaagtaaaga cagggaaact tatgccagca gaccaagaag
    20581 gtaatacatt tacaataagt aatgttggaa tgtatggtat aactacattt acacctataa
    20641 taaatatgcc ttcaagtgca atcttagggg taggtgctac acaagataag tttgttccag
    20701 taaatggaga ggctaaaata aaacctataa tgaacttatc attaacatca gaccatagag
    20761 taatagatgg aacagtagct gcaaaattct taaaagattt aaaagaattg ttagaaaatc
    20821 ctttatcaat gcttgtatag gttttgatat tttgttactg atataaatag tttgaataga
    20881 ttatattatt ataattgttt cagtaaattt aaagctttta tatattaaga attattttta
    20941 acagtaacta tatgtgaata tgatttgctt aattaaaata tatgaaaata aataggagga
    21001 gagcctatgt cagtagaagt aataatgcca aaagcaggag tagccatgga agaaggtact
    21061 atagtatctt ggctaaagca agaaggcgaa gaagtaaaga ttggagaacc tatactagaa
    21121 ataacaacag ataaagttaa tatggagata gagtcagaag gagaaggtac acttgctgta
    21181 atcatacata aagaggaagg tgaagtatta ccagtattta cagtaatagg tgtaatagca
    21241 gaaaaagggg aaaatcaaga ggaagtaaaa gctaaatatt tatctggaaa tgtttcaaaa
    21301 gaagatatag ttgaagagaa tcaaaatata gaatttaaag aagaaaaaat aaacaaaaaa
    21361 gagtgtaatc atgattatga tgtagtggta ataggaggag gacctggggg atatttatca
    21421 gcattaaaag cagctctttt aggtggaaga gttgctttag ttgaagaaaa tatactagga
    21481 ggtacttgct taaatagagg ttgtatccct acaaagactt atataaaaac agcagaaata
    21541 ttagaagaaa ttgaccaatt atcaaagaga ggtgtaaaag taactgtaga taaagaacag
    21601 gacattaaga aggccataaa atataaaaat agagtagtta aaaaacttac agctggtgtt
    21661 ggcggattat taaaaagtag agatgtagat gtgtttaatc ttaaagctag tgttaaagaa
    21721 gagcataaag taattttatc agatggaaaa gttttagata cagaaaatat aataattgct
    21781 acaggttcca aagtaaggat attacctata aaaggaatag aatcaaattt aataataact
    21841 agtacagaag cattagattt ggaaacagtg ccagaagaat tagtaataat tggtggtgga
    21901 gtgattggtt gtgaatttgc agagatattc aattcaagag gttctaaagt aactatagta
    21961 gaaatggaag atagagtaat cccaagaatg gataaagagt taagcgaatc tttaaaatat
    22021 tctcttagta aaaaaggtat aaatgtatta actaaaaaga aagtttctga atttaaagaa
    22081 gaaggaaata acatattagt gtgcattgaa ggtgaagagc caataaaagc agatttatgt
    22141 ctatatgcta taggaagaga agctaatctt tctggcatag aggacttaga tattaaaata
    22201 gataaaggtt caatagttgt aaatagtaaa atggaaacaa gtataccaag catatatgca
    22261 gtaggtgatg ttactggagg tgtaatgtta gctcatgctg cttttaaaat gggagaggta
    22321 gcagcttcaa atgctctagg tgtgaataaa gaagttgact taggtgcatt acctagttgt
    22381 gtttatacaa ttccagaagt agcatcagtt ggtattacag aagaggatgc tagaaaaaaa
    22441 tataatgtaa aagttggtaa gtttaatttt gctggaaatg gaagagcttt agcttctggt
    22501 caagaacaag gatatgtgaa ggtagtagca gatgctaaat atggagaaat tttaggtata
    22561 catatgtttg gatgtggtgt agcagaactt ataaatcatg cagcatcatt taaagcgtta
    22621 gagataccta ctgatgaagc aagtgagttg atatttggtc atccatgtac ttcagaagct
    22681 ttaatggaag ctttggcaga tgtaaatgga gaatgtttac acttacctaa aaaataaatc
    22741 taaacataaa ttattaattt aagtctatta ttaatattaa tttatatcat aaaattttaa
    22801 aacacttact tagccatacc ccttattatg caaataattt atttgcataa taaggggtat
    22861 tttttatgga aaaatataga atatagaatc cttgtagttt ttgttgtaca aaaaagatag
    22921 taatataaaa taacattatc attttagaat gatttcaatt gtaattagga aaagtgattt
    22981 ttttgttttt aaaaaaagta ttatttgtaa aatataaaaa aaaatttctt aatatttgaa
    23041 taaaagaata gcttaattta aatgttatta ctttataaaa aaataataag tacaaaaaaa
    23101 acaatatatg gcatataagt tgctatataa ataataagga gggaacaatt ataaatgagg
    23161 caaagaataa aaaacttaat tgaaaatgaa gataagaaaa atcctttaac agatgaagcg
    23221 atttcaagta ggttaaatat tcgaagagaa gatgttacct ttttgagaaa tgagttaaaa
    23281 atagaagatt caagacaaag aagaaaagtt gttttaatta aagctataaa agatatttta
    23341 aaagaagaaa aaactataaa taaaaatgat ataacaagaa gattaaacag cattgggttt
    23401 acagtatcaa gatttacagt catacaatac ttaaaagaga ttcaagattc tggtgaccta
    23461 aaacttgata aagagagtga tgataaaaaa gaagaaataa tcaataatag agaaaataaa
    23521 gatatagcat ttgataaact tataggtagt agtggtagct taagtacaat tataaaacta
    23581 gccaaagcag caattcttta tccacctcat ggtcttcata ctattattat ggggccaact
    23641 ggtgttggaa agagtgagtt agcagagtgt atgtataaat ttgcagtaga atcatccaga
    23701 ttccctaaga atgcaccatt tatagttttt aatgcagcag attattcaga gaatccacag
    23761 cttttgctat cacagttatt tggacacgtt aaaggtgctt ttacaggagc tgatgagaac
    23821 aaagaaggat tagtatcaaa ggcagatgga ggaatattgt ttatagatga aatacataga
    23881 ttacctcatg aaggtcaaga aatactattt caactgattg ataaaggtat ggtcagaaag
    23941 ttaggagaaa caagactaac acataaaata gatgtaatga ttatttcagc aacttctgag
    24001 ccaatagatt ctcatttact taatacattt aaaagacgta tacctgtaac aattgaaata
    24061 ccagaattag ttgcaagacc attaaatgag aggtttgaca ttataaataa tttcttctta
    24121 atagaagctc aaagaatggg agcaaacata catataaagt cagatgtatt aaaagctctt
    24181 atgctttacg attgtatagg taatgtaggt caacttagaa gtgatattca agtagcttgt
    24241 gctaggggac tattaaacca acttacaaac aaactaaaag aagtaaatat aagcatatca
    24301 gatgtacctg gatatgtaaa acaaggtctt ataaaaatca gaaattgtag agggaaaata
    24361 gaaaattatg tagatgggga tttaattata gactcaaatc ttcaaggtga gatagaaaag
    24421 aaaaatgaag atatatatac ttttccagat gaaatataca aacttactga aagaagacat
    24481 attgatttat tggaacaagg tttagatttt gatgttataa atagaatcat tggaggagaa
    24541 ttagaaagtt gcattcaaaa atacataaaa caagttaaaa aagtttctat tagtaacaat
    24601 cttccagata taagtccaat tgttggaaaa tatatcgtag agctaactta tgaagtaatc
    24661 aaaatagcat cacaatacct aagttcacta gaaccgaatc tacatttatg tttagcagtt
    24721 cacctaaaag cagcttttga gagattaaaa gaaggaaaag taatatcaaa tgctcatttg
    24781 aaagaaataa taggaaatta tccagtagaa tattctgtag cagaaaaggt agctcaatat
    24841 ttaaaggaaa gatataacat aaacttacca aaagaagaaa taggtataat agcaatatat
    24901 tttaaaatga gtagtagaag agatatgtct gaacaaaaaa agataggcgt acttcttatg
    24961 gctcacggaa gagtagcatc ttctgtatgt gaggttacaa ataaactatt aggaattaat
    25021 cacgcaaggt atttagatat gccatttgag aagaagccgg aagaaatgat tgaagaagct
    25081 actacaataa taaaagatat tgatgaaggt agaggtgtga ttatattagt agatatgggt
    25141 tcactttcat attttggaga tattatttct ggaaagactg gaattaatat aaggacaata
    25201 tctagatttg atacattgct ttctatagag gttatacgaa gagcagtttt accagattta
    25261 acaatagacg agatagttga tgaagttaaa ggtatagagc cacaagtaaa agaaaaggtt
    25321 agtaaatgta acaatacaaa agtagatttt agaaaaccta taattttaac attatgtatt
    25381 actggattag ggggagcttg taagataaaa aaaatcttag aggaaaatat taaaagtata
    25441 actgaaaagg ttgatataga acctataggt atgattgaat atccaagtct tgatttagag
    25501 ataaaacaaa taagcaatga taaaaatgta atcgccatag ttggaacaat tgaccctcag
    25561 atagcaaata tccctttttt tagtctagta gacataaatg ataaagcgaa gttaaatcaa
    25621 ataaataacc taattgatac aaatcaaatt ggtgaaacaa ataaaaaata tgaattatca
    25681 gatttaatac ataaagaaga tatatttgtg gatttacagg ttaaatcaaa agaagaagtt
    25741 ctaaaatata tgagtaaaaa acttagagag aaaggttatg tgacaaaaaa tttctataaa
    25801 aaagtagtgg aaagagataa cttatttcca actgaattat cagatgaaat agcaatacct
    25861 cacacagatg gaatagatgt aattaggcca gctataagta tagccatctt aaagaagcct
    25921 attgtgtgga gtaaaagtaa agtaaaaata atacttttat tagctgtaga ccaaaagtgt
    25981 tttaatccat taagcactct actctcattt atagaaacag atgaatttaa gaagataaaa
    26041 aacattaaag atagagattt tattagggag atgatattag atggagtcaa tgaaaataat
    26101 tagtagcaat ttaattttta aaaatattga agtgtctaac aatgaagatg cattaaagtt
    26161 tttgggacaa cgtttgtttg acgaacagta tgtaaaagaa agttacatac aagctgttgt
    26221 agcaagagaa aaaaagtatg ctacagggtt accaacagaa atatacggag tggcaatacc
    26281 acatacagat atagtacatg taaatgagcc aggaatagca attggaatac tgaataaacc
    26341 tgtaaaattt ataatgatgg gtacagacga tactgaaatt gatgtaaaag ttgtatttat
    26401 gttagcagtg aaagagccac aagaacaatt gcaactatta gaaaaactta tgactatatt
    26461 tcaagataag aatatactaa ataatattgt tgacttaagt gaagaaagtg tgagtgattt
    26521 attaaactct aaattgaaaa attaaacatg taaagtatat taaaaatgta aaattaaaca
    26581 tgcaaagtat gttaaaaaat ataaaaagat tattaaagat ttctaactat agatatcttt
    26641 aaaataaaat aatttcaatg ggggtgacta atgtggctaa aaagatatta gttgcatgtg
    26701 gaacaggagt atgtacttca acaattgcta taaacaaatt aaagaaagca cttcaagaca
    26761 ttggtaaatt ggatatggtt aatattacac aatgtaaagt agtagaagtt gcatcaaaag
    26821 cacctgatta tgatttaata atttgtacta cacaagtatc tagtagtata aaaacaccag
    26881 tgataaatgg attacctttt ttaactggtg tcggaatgga taaattaatc aatgatgtat
    26941 tagaagagtt agaattataa ttaaaaaaat taaggaacat ggtctctaaa atcataagtt
    27001 ttagagactt aaaattaaat aatggagggt ctttatatgg agatattaaa tttcattgtt
    27061 ggtctaggtg cacaagtaat gatgccaata ataatatgta tttttggttt gatattaggt
    27121 acaaaactag gaaaatcttt aagagctggt ttaactgtgg gagttgggtt tataggtctt
    27181 aacactatta tagctttgct aacagataat ttaggtccag ctacacaaca aatggttaag
    27241 aatttagggc taagtttatc aataatagat gtaggatggc cagcagcatc agctatagct
    27301 tttgcatcaa cagtaggggc tttaattatt ccaataggtc ttgtggtaaa tatagttatg
    27361 ctaattacta atactactca aactgttgat gtagacatat gggattactg gcattttgct
    27421 tttacaggag ctttagtggc aggtgctact caaagtgtaa tgtggggagt atttgcatca
    27481 gtagcaaata tggtaattgt attggtaatg gcagatttaa ctgctccagg tatagaggaa
    27541 tatttaggta tgccaggtat atctcttcct catggattta cacaggcatt tgttccaatt
    27601 gctatagtag taaataaatt attagaccta ataccaggta taaataagat tgagataaat
    27661 gctgatacat tgcagaaaaa atttggatta tttggagaac ctttaataat ggggtctgta
    27721 ataggtgtaa taattggtat tgctgcgaaa tatgatataa aaggaatatt acaattaggt
    27781 gtaactatgg gagctgtatt aatattaatt ccaaagatgg cagcattatt aatggaagga
    27841 ttattaccag tatcagaagc tgcacaggaa tttattgaga agagatttaa aaacagaggc
    27901 aagatttata taggcttaga ttcagcagta ggaataggtc atcctgttac attatcagtt
    27961 gcactagtgt tggttccttt gactatactt atagcagcta tattgccagg aaataaagtt
    28021 ttaccatttg cagatttagc agtaattcca tttgcacttg tattaatcgt accaattaca
    28081 aagggaaatg tgtttagaac attaataata ggaataatta taattacttc tggattatta
    28141 atcgcaacta acttagctcc attatttacc caaatggctt taaatgctag ttttaaaatg
    28201 cctgaaggag caactatgat ttcaagtatt tgtgatggtg cgaatccatt aagttgggta
    28261 tttgtaaaag ttatgaacta taaagttatt ggaggagtag tttttggagt tatagcttta
    28321 ggaatggcta tttacaatag gaatagaata ataaatgaaa ataaaaagct atctatagaa
    28381 gaataaggtt aaaacaattt tattaaggag tgtataggtt atgaaaaaat ataaatatga
    28441 ttctaaaaga tacttactca gtgttacaat accaggattt tttatgattt taatattgat
    28501 ttatgcactg tttaataact atacaaattt taatttgaat atatatagtt tgttaataat
    28561 tgtctgtact tatggtatat tcaatacttt tatatcatca agtaatccta aaaaaattat
    28621 tattgatagc aaatgtatac attttacctc atttatgact acacataagt atgaaattaa
    28681 agatatagaa aagataagaa taagagaatt ttataataaa aaaatttatg taaaaattaa
    28741 tgatggaaac ctttttaaag gtaggtattg gataagaaca aatatgttta ataatagtat
    28801 agcattatat agctatttca ttgagttgga agagtgctta tatccagatt cactaaaatt
    28861 tagaaataaa aaatttgaga ataagaacat ataaaaataa aaaattgaat tgaagcctag
    28921 cttaatcttt tttgataaga tataagtttg aactttatac taaattttta gaattttcaa
    28981 tcaagacaat aacataatag ctaagcaatt agaacacaat taagatgtat aaggcatgta
    29041 tatgatgaat gggaggattt aattaatgtt attagagaaa ttaagaaaag aagtattaca
    29101 agcatcttta gaccttttaa actataattt agtgacatta acaggaggaa atgtaagtgg
    29161 gagagatgaa caaactggct atatagcaat caccccaagt ggaatggatt atagaaatct
    29221 tacaccaagt gatattgtta tagtagatgt agatggaaat attatagatg gaaaatggaa
    29281 agcatcagtg gatttatcag accacttgta tatatataag catagagaag acataaatag
    29341 tataattcat acacattcta catactcaag ttgttttgct attttaaatg aacctataga
    29401 atgtgcaagt acaactcttg caaatgaagt agggggttca gtaccagttg caaaattttc
    29461 accaccaaca tctaaaaaga tgggaaaatg tgttattgaa gcaattggtg acaaaagagc
    29521 atgtctttta gcaaatcatg gcgtaattgc agttggtcca tctgtaggac atgctcttac
    29581 agccgctgta atgttagaag attcagcaaa agtatattac ttagcaaaat caattggcac
    29641 accagtgcta ctgcctgatg aagaaattca aagagcgaga gatgtatttt ttaatgtcta
    29701 tggtcaggat aaataaatta gataaaattt taaaagtaat atgaaaatat agatattcaa
    29761 tgatattaag gagatttata atgatataat aagtttaata gttaagaagt aaaatatgaa
    29821 atgtaatagt atataaattc atttaagact aaaaagaata agataaaata aaaaggagtc
    29881 tgtatttcta tgtattactt attaaacaaa agcacaaatc cttactttaa tttggcatta
    29941 gaagaatatc tatttttaaa tgataaatat aatgatgata ttataatcat atggagaaat
    30001 gaagaatcca tttttatagg taaaaatcaa aatccatatc aggaagtata tcatgatgtt
    30061 attgaaaagg gagaaattcc tattttaaga agaatatctg gaggaggaac tgtttatcat
    30121 gacttaggta atatcaatat gtcattcata caaaaagata ggcaacttca tgagatagat
    30181 tttttggagc atactaagtt tatgcaaaag atgctttcaa ccttaggact agatgtatct
    30241 ataactgaaa gaaaagattt atttttaaat gggaaaaaaa tttcaggctc tgcacagtct
    30301 ataaaaagaa aaaattctct ttatcatgga actcttcttt acgattcaga tttaaataaa
    30361 ttaactaaat atttaaattc aaataaagca actgaatcaa atgcaactaa atctgtttca
    30421 agtaaagtta caaatattaa gtttttactc gaaaaagata taaattactt tttagattat
    30481 tgtgttgaat atttaaaatc taatataaag aatataaaag aacttgaatt ggatgaagaa
    30541 gatattaaaa gtgtatacaa tataggagaa gataaatata aaaagataga gtggacatat
    30601 ggtaaaacgc cgaaatttca agtagtgcta ccatttaata atgaaagtaa aataaatata
    30661 catgttaaca gatggaaagt atcaaaattt tttatttctt atgatgataa tgtaattaat
    30721 atggacaagt tgttagattt gaatttcttt aaagaagaaa taaaagagag tattttagaa
    30781 aattatccac attacataga tttaatcaat ttaatatttt aatataaaac ctctaatttg
    30841 ataaaattgt cttatatcaa actagaggtt tttaatattc ttgcatatta acaaccatta
    30901 caaaattgta aaattaaaaa caacactatt gaaaaatcaa tatatattgt aataaatata
    30961 tgtgtttttc attagcaaat agacattaac tatttataca actgaaaatt taatatataa
    31021 ttaatcagat ggttaaaata aaaatattaa aagttttaat aaatgatggt taaaaataaa
    31081 atacgaggtg ataccatgta tagtgttata attgttgcag cgggaagcgg aaggagaatg
    31141 aacttagata taaacaaaca gttcataaaa ttaagagaaa aagaaattat tgctcataca
    31201 attcaagttt tttatgaaaa tataaatata gatgaaatag tggtatgtat aaaaaaagaa
    31261 gaagaagatt tttttaaaga aaatataata aataagtata actttaaaaa tataaaaata
    31321 gcatatggcg gaaaagaaag acaggactca atatataatg gtttaaaaaa attagatgaa
    31381 aattgtgata tagtacttat ccatgatgga gcaagaccat ttgtcgacca tagaataatc
    31441 aatgaatcta taaaggtagc taaagaaaaa aaggctgtgg ttgtaggtgt tccagtaagt
    31501 gatactataa agatagtgtc agatggaaca gtacaagaaa ctccagaaag aaatttgctg
    31561 tgggcagcac aaacccctca aacctttgaa tataatctca taatagatgc ttatgaacaa
    31621 gcatataaga acaattatta tggtactgat gattcaatgt tggtagaaaa tataggtcaa
    31681 agtgtcacta tggtaatggg ttcttatgaa aacataaaaa taactagtcc agaagattta
    31741 aatatagcag aacaaatatt aaatatggaa aaaagagatg aagttaacag tagaaggaga
    31801 attatatgag aataggatta ggatatgatg tacacaaatt aacagaggat agaaaactta
    31861 taatcggtgg tgtagagata ccacacgata aaggtttgtt gggtcattct gatgctgatg
    31921 tattgataca tgcaataatg gattctattt taggtgctct agcattagga gatataggga
    31981 agcatttccc agatacagat gaagaatata agggagcaga tagtatgaaa ttattagaac
    32041 atgtgtataa tctaataaca agtaaaggat ataaaattgg taatatagac agtactataa
    32101 ttgctcaaag ccctaagatg gctccatata ttgagagtat gagaagtaat atatcaaaag
    32161 ttttaaacac agacattgat aatataaaca taaaggcaac aacagaagaa ggtcttggtt
    32221 ttacaggagc aaaacaggga atagcttcac aaagtatttg tttattattg ttgacaagtc
    32281 agaataatta atatattatt agtaataagt ttaatggata tcaagtaata ggcctatata
    32341 gaatatctat aatgtatgaa tttaagtgaa attaatataa atataaaatt agctatgata
    32401 aagaaatagt aaaatgatga aatcttcaca gagagaaaac ggtggtgaga gttttcaaga
    32461 ggaagtcttt gaacctgtct tttagcttaa aggtataaaa atctttacgg taggaaccgt
    32521 tatattccca aaagagagct attcatatag ctaactagag tggtaccgcg gaaattaaac
    32581 ctttcgtctc tatacttgta tagagatgag aggtttttta tattttcagg aagttaatat
    32641 tcaggaggaa tctattaatg aaaatgtcaa aaatgtttat gccgacatta aaagaaatcc
    32701 cagcagatgc tgagattaca agccatcaat taatggttag gtcaggcatg ataaaaaaaa
    32761 tgacttcagg tgtttataac caattaccaa tggggttaag agtgttcaaa aaaattgaac
    32821 aaataattag agaagaatta aataaaaaag attgtcaaga aatactttgt gcagccttac
    32881 ttccttctga attatggaaa gagtctggaa ggtggactgc tatgggtgaa gaaatgttta
    32941 gactaaaaga cagaacagaa agagagtact gtcttgggcc aacacatgaa gaagcattca
    33001 ctgatataat aagacaagaa attacttcat ataaacaatt gccactaaac ttgtaccaaa
    33061 tacaagtaaa atatagagac gagagaagac caagatttgg tgttatgaga actaagactt
    33121 ttacaatgaa ggatgcatat agttttgatg tagatgataa aggtttagat aagtcatatc
    33181 aagatatgtt tgatgcatat gtaagtatat ttgatagatg tggattggag aatagccctg
    33241 tacaggcaga ttcaggagct ataggaggtt ctacatcagc cgaatttatg gttaagtcag
    33301 aagttggtga agatgaagtt gtattttgta gtggatgtga ttatgcagcc aatgtagaaa
    33361 gagcagaatc ttgtaatcta gcatcacaaa aagaagaaat gaaagaatta gaagaggttc
    33421 atacaccagg agcagctaca ataaaagagt tagaagaatt tttaaaaact tctccagata
    33481 agtttgctaa aactttagta tatgaggcag atggaaaaac agttgtagtc gttgtaagag
    33541 gagatagaga agttaatgaa atcaaagtat ctaatgccat aggttctgtt atagaatttg
    33601 ctcttgctac agatgatgta gtgagaaaag taactaatgc agaagtagga tttgcaggtc
    33661 caataggtat aaatgctgac tatgtattta tagataaaga aattgttgaa caaagaaaca
    33721 tagttgttgg ggctaataaa actgagtacc atataaaaaa tgctaactat ggaagagatt
    33781 ttgaaggaat agttggagat tttagaaatg ttcaagaagg cgacaagtgt atagtatgtg
    33841 gtaagccact tgaaatagct agaggtgttg aagtaggaca tatatttaaa ctaggaacta
    33901 agtactcaga atctatgaat gcaaacttca tagacaaaga tggaaaatca aagcctatag
    33961 taatgggatg ttatggaata ggtgttgaaa gaacagcagc agctataatt gaacaacata
    34021 atgatgagaa aggtataata tggcctttgt cagtagctcc ataccatgtt gtgatagttc
    34081 cagcaaatat gaaaaatgaa gaacaaatat caatagctga aaatatatat aatgatttgc
    34141 aagctatggg tgtagaagtt ttattagatg acagagatga aagaataggt gtcaaattca
    34201 atgattcaga attaatagga atacctatga ggattacagt aggtaaaaat attaatgaag
    34261 gtaaagtaga atttaaactt agacataaag aagataaaga gataattgac atagaagaaa
    34321 taaatgaaaa agtaaaggca gagtttatca ggaataatgt taggttagga taataactta
    34381 aataagatat tgtatagata atcaaagttg tactttatag acaccatttt atctatatat
    34441 aaggatataa aatggtgttt ttttataaaa caaataaatg aggaggtaat taaaatggca
    34501 aaaaatgaaa aacaatttgt tgaagaaata acaaagatgg aagatgattt tccacaatgg
    34561 tacacagatg taataactaa gactgactta gttgattatg caccagtaaa aggttttatg
    34621 gttgtaaagc catatggata tgcattatgg gaaaagatgc aagaatttat ggataaaaaa
    34681 tttaaagaaa ctggacataa aaactgttat tttccattat taataccaga gagtttatta
    34741 aacaaagaag cagaacacgt tgaaggtttt gctccagaag ttgcatgggt aacacatgga
    34801 ggaaataaaa aattagaaga aagattatgt gtaagaccta cttcagagac tataatatgt
    34861 acaatgtatg cgaaatggtt aaaatcatat agagaattac catatcttta taatcaatgg
    34921 tgctcagttg ttagatggga aaaatcaact agacctttct taagaacatc tgagttttta
    34981 tggcaagaag gtcatacgtt acatgaaaca gcagaagaag cacaagaaga aacaatacaa
    35041 caattagaag tatataaagc gctatgtgaa gaattacttg caatgccagt tgtagctggt
    35101 caaaaaagtg aaagtgaaaa atttgcaggt ggtgaaagaa catatactat agaagctatg
    35161 atgcatgatg gtaaagcatt acaatcaggt acaagtcact tcctaggtca acactttact
    35221 aaggcttttg atattacttt tgcagataga gaaggaaatt tagctaatcc atatcataca
    35281 tcttggggag catctacaag acttataggt ggacttataa tgactcatag tgataacaga
    35341 ggtttagtat taccaccaag agtagctcca attcaagttg ttatagttcc tatagctgct
    35401 aaaaaaggaa atgtaatgga gactgttgat aaaatatatg ctgatttaaa agctaaggga
    35461 gtagctgtag aagttgatga tagagataac tatacaactg gatggaaatt taatgagtgg
    35521 gaaatgaaag gtgttccagt aagagttgaa attggaccaa aagatataga aaataatcaa
    35581 gctatggtat ttagaagaga tactttagaa aaggattcta tgcctttaga aggattagct
    35641 gatgctatat gtgatttatt tgatgttata cacaatgata tgtttgaaaa agcaagaaaa
    35701 catagagaag acaatacatc tatagttgaa aatatggatg agtttagaaa agctttagaa
    35761 gaaaagccag gattcataaa gactatgtgg tgtggagatg cagaatgtga agctaagatt
    35821 aaggaagaaa caggagcaac tataagatgc ttaccttttg aacaagaaaa cttaggtcac
    35881 aagtgtgtgt actgtggaaa agaagcagat agtatggtag taatggcaaa agcttactaa
    35941 aatacattta aataaaaact ggggtagaaa gtatttaata ctttatccca gtttttttgt
    36001 tttttatgag taataaaatg tatttgtaac tatgtcataa gataagtcat agatacttat
    36061 attaaaaaga atataataga gaactatttt taataattac atattaatga aagcaaaata
    36121 tttttgttat atagattttc aataaagcaa acaataaata taaatgaata ttagtaagga
    36181 gtgcttttaa tttttagaaa ataaatgact taaaagaaag atttatgaaa ttaaaactag
    36241 gattttctga tataataaac atgtgtattt ttaaataaaa aggatattat tattagattt
    36301 gattaaaaat aaacttgcaa aacaatgtac tagtttaata ttatagttat attgaataaa
    36361 atatcaggag gaagtaaaaa tgaatgtaag agtaaggttt gcaccaagtc caacaggatt
    36421 tgtacatata ggtagtttga gaactgcttt atataactat ttatttgcaa aaaaaatggg
    36481 cggagaatat atattaagag tggaagatac agaccaaagt agattagtag aaggtgctat
    36541 agagaatatg cttaatgcta tgaaatgggc tggggtcaac catagtgaag gtgttatatt
    36601 agatgatagt ggaaaagtag tacaaaaagg agaatatggt ccatatattc aatctcaaag
    36661 attagatata taccaagaat atataaagca acttttagat agtggaaaag cttattactg
    36721 tttctgtaca aaagaaagac tggatgaagt aagagatgct caaagagcag caggagaaac
    36781 agctaaatat gatggtcatt gtaagaatct ttctaaagaa gaagtagaag cgaatataaa
    36841 agcaggaata ccatatgtta taagattaag attgccagag aatcatacaa ttaagtttac
    36901 agacttagtt agaggagata tggaatttaa tactaatgac ttagatgacc aagtattaat
    36961 gaaaacagat ggatttccaa cttatcattt tgcagtagtt gttgatgact atttgatgaa
    37021 aattacacat gttataagag gagaagaatg ggtatcatct actccaaaac atgtttattt
    37081 atatgaagct tttggatggg aagcacctgt atttgtgcat ttaccaaata tacttaataa
    37141 agaaaagaaa aaattaagta aaagacaagg tgatgtagct gttgaagact ttaagaaaaa
    37201 aggatattta ccagagggat tagtaaacta tgtagcatta gttggttggt ctcctgaaga
    37261 taatcaagaa ttgtttacaa tggaggaatt agaaaaagcc ttctctgtag aaagagtctc
    37321 taaaagtggt ggagtatttg atactgaaaa attaaattgg gttaatcagc attatataaa
    37381 agatggtgat gatgcttatc taacagactt agcaatacca tttttaatag aagatggatt
    37441 tataacagaa gaagaagcta ctaataaata tgatttctta aagagtatga tatcagtact
    37501 taaagagaaa ttacaatatg taaaagaagt tactgaacat gcaagtatat tttttggaga
    37561 taaaatagag gtagaaactg aagagggaag agagttctta agattagaac atatacctac
    37621 tttaatagat gctttgagag aaaaaataga aaaaacagag gtattaaatg ctgagtttgt
    37681 tcaagctatg cttaaagaaa tacaaaaaga gtacaaaata aaagggaaaa atttatttat
    37741 gggctcaaga ataattttga cagggcaaat gcatggtcca gatttaccaa aagtaatgga
    37801 agttttagga aaagaaactt gcttaaatag aatagcttat gtaaaaaata atatattata
    37861 gtcataaaag tccgctaatt tagaagcgga ctttttttgt gttagtattt ggtgaaaata
    37921 tctgcttaag aaaatgaagg tatttaaggt aataaattta atatataaaa agcaaagcaa
    37981 aaatataaat aaaatatgaa taataaacta ataaaatatt aagcatagaa gaagggaatc
    38041 tattatttta gtttgattta attattaagg gggtaattac tatgtatagt aatattgatg
    38101 atgttaaaaa ggaattaaag gagctatgct tagaatatgt tacaatttta gaaaaattaa
    38161 aagatgaaaa aatgattaca gaagaaactt ttgaaaagtg ctcttctcaa aaaaaaatat
    38221 ttttagaaga acaatagagg atggtaatag tattattatt atgtagtttg aaagatagta
    38281 cgaaaaatga tagtaatact attatttatt gcaattttca actataatat aatatataat
    38341 gttaagaaga taatttataa aaatacagtg aggtgatgag tgtgaaagtt tataatacat
    38401 tgactagaac aaaagaagaa tttgttccat tagaagaagg aaaggtaaaa atgtatgtgt
    38461 gtggtccaac agtttataac tatatacaca taggtaatgc aagaccattt ataatatttg
    38521 atactctaag aaggtattta gagtatagag gatatgatgt aacttatgta caaaacttta
    38581 cagatgttga tgataagatt ataaatagaa gtcatgagga gggaatatct cctgaagaag
    38641 ttgcggctaa gtatataaaa gaatattttg tagactgtga tgggctagga ataaaaagag
    38701 ctactgttca tcctcaggtt acagataata tacaacagat tatagagttt ataaaagagt
    38761 tggaagataa gggatatgca tatgcagtaa atggtgatgt atattttgat acaaataagt
    38821 ttgaaggtta tggaaaactt tcaggtcaaa aacaagaaga tttagaggca ggggctagaa
    38881 ttgaggttaa tgaccaaaaa agacatccta tggactttgt tctttggaag gcaaaaaaag
    38941 aaggtgagcc aggatgggat agcccttggg gagaaggtag accaggatgg catatagaat
    39001 gttctgttat gtctaagaga tatttaggtg aaacaattga tatacatgca ggtgggcaag
    39061 atttaacatt cccacatcat gaaaatgaaa tagctcaaag tgaagctaga agtggaaaaa
    39121 cattctcaaa atactggatg cataatggat atataaatat aaatgatgaa aagatgagta
    39181 aatcaaaagg taatttcttt acagtaagag atatatcaaa attatatgat ttagagatag
    39241 taagattttt catgttatca gcacattata gaaatccagt aaactttagt gatgagatgt
    39301 taaatcaagc taaagcaggt cttgaaagac tatataatac taaagaaaaa ttagaattta
    39361 cgctaagtaa tttagtagaa tctcctttaa cagaaaaaga agtagagctt gttaaagaat
    39421 tagatgactt tagacaaaaa ttcatagatg ctatggatga tgatgttaat acagcagacg
    39481 cagtaagtgt aatatttgaa ttagctaagt taataaattc taatgtagat gaaaattctt
    39541 ctttggagtt tgctaaaaaa tgcttagatg aatttaatga acttacagga gtattaaata
    39601 ttgtaaataa gaaaaaagat actgtattag ataaagacat tgaagaattg atacaaaaaa
    39661 gaactgatgc aaagaaaaat aaagagtttc aattagctga tgatattaga caacaattac
    39721 tagatatggg aattgtatta gaagacacaa gacaaggtgt taagtggaaa aggatataaa
    39781 aatggaaaaa actgaattag ttactatgtc accattagtt ttagcatact taggtgatac
    39841 agtgtatgag acatatataa gagaatattt aattagacag aatacacaaa gaaaagttaa
    39901 tgatttgcat aaactagcta taaagtatgt aaaagctaaa gctcaggcaa ctataattca
    39961 tgaaattgaa attgagttaa ctgaagaaga gagtaaaatt tataaaaggg gaagaaatca
    40021 aaagtcaaat acttctccta agaatgcaga tattatagac tacaaacatg caactgggtt
    40081 tgaggcatta gtgggatatt tgtatttaaa taatgaaata gagagacttc aatatattat
    40141 caataaagga atcaaaatta ttgaaagaga tatgtaaata ttaaagagtg ttgtcttaat
    40201 aataagtaat aaggcaacac tttttttata actaatgtat aataaatata tagaaattag
    40261 taatgagaaa ggataaaaag ttatgaaagt aaaattaata tcacatacac ctgaaccaga
    40321 aaaagtaata gctatggcag ctaagctatg ttattcacca gttgggacag acgaaataga
    40381 aaaagactta acagatgaaa gtatagagaa atttttaaat atgttattaa gtataggtca
    40441 tgggtcaata ttagaacatg cttcatttac attttcaata gaaggtattt caagggcttg
    40501 ttcacatcaa attgttagac atcgtatagc tagtttttca caacaaagtc aaagatatgt
    40561 taaattagaa caatttgagt acataattcc tccagaaata gaaaaaatag aaaaggcaaa
    40621 agagttattt atagactcca tgaaaaaaga ccaagagaat tatgataagt tagttgaaat
    40681 attgtttgaa aatcattata atgacctaat aaaaaacggt aaaaatgaga aaacagctaa
    40741 aagacaagct gaaaagaaag caatagaaga tgctagatac gtatttccaa atgcatgtga
    40801 aacaaaaatg gtatttacta taaatgctag aagtttgttt aatttctttg aacatagatg
    40861 ctgtgaaaga gcacagtggg aaataagaaa tttagctgtg gagatgttaa gagaggttaa
    40921 aaaggttgct cctatattat ttaaaaagac cggtccaagt tgtgtaaatg gaagttgtcc
    40981 agaaggaact atgacttgtg gagatatagt tcaagttaga gaaaaattta aggccttgta
    41041 ggaggtgaat aatttggcga gtatagaagg aagaaatccg gtaatagaag caataaaaag
    41101 cgacagagaa atagataaaa tattaattgc aaattcagct aaagaaggtt caattaagaa
    41161 aataatagga atggctaaag ataagaatat aattattcag tatgttgata aacataagct
    41221 agatgaagta agtacaagtc attcacatca aggtgtaata gcttatgcaa gtgagtataa
    41281 gtattatgaa ttagatgagc taatagattt agcaaagaat aaagatgaag acccattttt
    41341 cattatatta gatgagataa cagacccaca taatttgggt tcaataataa ggacagcaga
    41401 tgcagtagga gcacatggag ttatcattcc aaaaagaagg tctgtacaca taactcctgt
    41461 agttgccaaa gcatctgctg gagcagtaga atatatgcca gtttgcaagg taaccaatat
    41521 agttaataca ataaaaagac tcaaagaaga agggctgtgg attgctgcag ctgatatgga
    41581 tggagaaact ttttataaac aaaatcttac tggtcctctt ggtgtagtaa ttggaagtga
    41641 aggttttgga atatctagat tggttaaaca aaactgtgac tttatagtaa aaatgccaat
    41701 gataggtaat gttacatctt taaatgcatc tgtagcaggt ggaatacttt tatatgagat
    41761 attcagacaa agactggata aaagtaaata ggcatgaaaa aaaatataaa tcattactta
    41821 ataatagatg gctacaatat tataaatgcg tgggacaatt tgaaagaact ggctaaagag
    41881 gacttagaag attctcgaga aaagcttatt gatgacatta tagaattttc tgagtttatg
    41941 ggttataaga ctataatagt ttttgatgct tataatgtta aaaattctcg agaaaaagtt
    42001 gaaaaaagaa aacacataac aatagtttat acaagagaac accaaacagc agatagttat
    42061 atagagaaat ttataacttc tttatcaaag tatgatgatg taaaagtagc cactaatgac
    42121 tatgcagaac agcaaatgat tttaggaaaa ggtgctacta gaatgtctgc aagagaatta
    42181 aagttagagt tagatcgttc caagaataaa atgaaggaaa aaaatatcgg tttgaggaaa
    42241 aaaattcagc gaaattggtt ggaggaaagg ttagataaag aaacattgtc gaaacttgag
    42301 aacattcgta gaaagcgttg aaattactag gttctttaga ctataatata cctataaatt
    42361 tgttttatat atgggggaga tttacatgtt ggtagcaaaa gaaaaaagtt atgagttagt
    42421 ggacaattgt cagcaggatg agtataacat tgtattaaga gcaagtgaag gggataaaat
    42481 agcactagag tacattatta ctaaatacag aaattttgta aaggcaaaag caaagtcata
    42541 ttttttaatt ggagcagata aagaagatat aatacaagaa ggaatgatag gcctttataa
    42601 ggcagttaga gattttgatg gaagtaagac caattcattt aaatgttttg cggagatatg
    42661 tataacaaga caaataataa ctgctataaa aactgcaaca agacaaaaac atataccttt
    42721 aaattcatat gtttctttga ataaaccaat atatgatgaa gagtcagaca gaacactttt
    42781 agatattata gctacaagta tagtaacaga tccagaagag cttataatta gtaaagaaga
    42841 gttaaaaaat atagaatcaa aaatgaacga attgttaagt gacttggaat tagaagtact
    42901 agaattatat ttaaatggaa agtcatacca gtttatagcg gacaagctta aaagagatgt
    42961 aaagtcaata gataacgctt tacaaagggt taagagaaaa ttagaaaaac atcttgaaaa
    43021 cagaaatgat taatagtaaa atacttacca taagcttatt gtgagcaaaa ttaatttata
    43081 tcgaaagata agggaggaaa ttcaaaatgg ctaaagctaa atacgaaaga acaaaacctc
    43141 atgttaatat agggacaata ggacacgtag accacggtaa aactacatta acagcagcaa
    43201 taacaaaaac attatatgac agatatcaat taggagaagc agtagatttc gcaaacatag
    43261 ataaagctcc agaagaaaga gaaagaggaa tcacaatatc aacagcacac gttgagtatg
    43321 aaacaccaa
//
LOCUS       DAMJVG010000029        41934 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.029, whole genome shotgun sequence.
ACCESSION   DAMJVG010000029 DAMJVG010000000
VERSION     DAMJVG010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 41934)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41934)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41934
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.029"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            302..1846
                     /locus_tag="PC512_001673"
     CDS             302..1846
                     /locus_tag="PC512_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HDF2441419.1"
                     /translation="MRNLQKKLMFFLFICIILQITYTTPVYSLCKLYKNNSINNFESI
                     VSNNQLISKHAIQIILIMAIICVILIFYIIYDKLNFKIKLQRIAYTDNLTGANTIDKF
                     VIDANKILCKNTQVKYALLYIDIDKFKYINDLFGYEVGNEILRNLTKIIKRNIFEEEM
                     FARISADNFIIIMKYIEEEDITKRLKTIFEELDLFNNNQEEKYKLVLSCGIYFILPED
                     RDINSIIDRANIPHKMAKGGHKSSYAFYDNKIHDQEIKEKEMENTMFSSLENKEFIIY
                     LQPKIELNTGEIQGSEALVRWKRPDKGLIPPNEFIPFFERNGFVINLDLYVLEEVCIY
                     LRKWIDAGINPVTVSVNVSRIHLYCNNFIETYKNIIDKYNIPAKYIELELTESIIFDN
                     FDILIDIMNNLKKIGFLISMDDFGSGYSSLNMLKEIPMDILKLDQKFIMETYNSKRSK
                     IIVTKVIEMAKELGMKVISEGVETEEQFKLLKEVKCDMAQGYLFGKPMPIEEFEHLIV
                     SNLVRG"
     gene            2022..2390
                     /locus_tag="PC512_001674"
     CDS             2022..2390
                     /locus_tag="PC512_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2441420.1"
                     /translation="MEWELDNNKPIYIQLVEHLKLKIISGEIKIGSKLETVRALAEDA
                     EVNPNTMQKALTELERQGLVYSQRTKGRFVTDDKEKIKAMKEEIANVEINTLKVTLEK
                     LGYDRDEMLKLITENLKGEL"
     gene            2392..3117
                     /locus_tag="PC512_001675"
     CDS             2392..3117
                     /locus_tag="PC512_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2441421.1"
                     /translation="MDKNISNVSQDGIVEFKGVNKSYGTKNVLKNIDLNIPKGKIVGL
                     LGPNGSGKSTMIKLMNGLLQPDNGEIMINGMKPSIDTKKIVSYLPERTYLNDWMKVSD
                     LLKFFYDFYSDFDVRRANEMIKSLDIDVNEKLKTMSKGTKEKVQLILVMSRNASIYIL
                     DEPIGGVDPAARSYILKTILKNYSEDSTLLIATHLISEIENICDEIIFISKGEIVLQG
                     DVEAIREEKGKSIDALFREEFKC"
     gene            3111..3875
                     /locus_tag="PC512_001676"
     CDS             3111..3875
                     /locus_tag="PC512_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2441422.1"
                     /translation="MLGKLLKYELKASGRIFIPLYIAILIVAVFNGIFMNTNILQVQG
                     IGILVLTSLFMALGVLTIVVTIQRFRKNLLGDEGYLMFTLPVSTSSLILSKCITALIY
                     AVLSFIVAVFTFGVLMLFGTSGILLPEILDLFNTSFKWISENFLDILLLVVVMFISYS
                     SFILLLYTSISMGQLPKFNKHRNIVAFASFIAINIVISIVGDAVGSILPNEDTNMVYH
                     LYQSPSFMLAILGSLVVAIALFFATKFILDKKLNLE"
     gene            4097..5347
                     /locus_tag="PC512_001677"
     CDS             4097..5347
                     /locus_tag="PC512_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2441423.1"
                     /translation="MKSYTKAKWSVWGIITFSFVLVLFLRMSTAVVSDNLANELGFNS
                     IQISNIASFCLYAYAFMQIPAGILIDKYGARKISSLGIIMASLGSILFGLIQSIELAY
                     ISRVIVGAGTSVILLCILKIQGRWFNKSEFASATAKFSFVGNLGGVLATFPLVFLSEL
                     VGWRNSFLLIGIIGVVIGCFMYIIVRDTPKEYGFNIDTEPYEKSEKVNIVDGIKSVIK
                     NKSTWYNSMIMFSFVGLTSAFISLWGVRYIMDVYGVSKSFSAFIVSFFTYGFIFGSII
                     MDFVFAKIRSSKFNIIKFGAMIDLFIWIVIVVVYQVKPPIIVLPISFFIMGCIVMSHL
                     QVFNDAKYKNKEIYSGLATSVINTFEFIGSGIINLIIAISLQVNSYNIVDGYKKGFVV
                     FIVLSIITIVSSHIGVKNDDFKAI"
     gene            5540..6424
                     /locus_tag="PC512_001678"
     CDS             5540..6424
                     /locus_tag="PC512_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HDF2441424.1"
                     /translation="MDTTKIDDISKLDLNNLDINKMDMGGIMESLLEWATTSGVKLII
                     GILILSIGFKIIKKFVNHVMLLLSKRDIDLTLRRFLKSLLLSVLKVAVIIIVLEYWGM
                     SLSSFAAVIASAGVAIGLALQGSLSNFAGGFIILLIRPFKVGDYVEAAGHGGTVEQIG
                     LFYTQLVTPDNKQILIPNGSVSNDSLINYSAKNTRRVDLTFSVGYEDDILHVRRVLKD
                     IVNNHKLIINEPEPFIGVVEHGDNAIKFATRVWCKTEDYWTIYLDLLEEVKVRFDEEG
                     ITIPYPKMDLTVKELNKI"
     gene            6783..7400
                     /locus_tag="PC512_001679"
     CDS             6783..7400
                     /locus_tag="PC512_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HDF2441425.1"
                     /translation="MCKKMYLLVVGILIAGLLTACNGSPTKDSEQAQDNTKKEANVSN
                     NALKDEKNNENLMEQDFKVPYTDAINIFKDKYKDADIVDLSLERDLNKFVYTVEGVDD
                     NNEYKMKIDANTKDVLEDKTEKLDSEDLNGVARKEKLDFNDIMTPQQAMEIALKEQNG
                     MVKEWSLDKDLDVTFYKIRIDKDKNEYDIKVDSKKGTVLKVEKED"
     gene            7508..10039
                     /locus_tag="PC512_001680"
     CDS             7508..10039
                     /locus_tag="PC512_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDF2441426.1"
                     /translation="MSLKSLKIKENLYWVGSLDPDLRVFDIIMYTPYGTTYNSYVLKG
                     TEKTVLFETVKDKHFDNYIERLNDLNIDFEKIDYIVVSHTEPDHAGSVEKLLDLAKNA
                     KVVASETAIKYLKEIVNKDFEYVAVTDGDTLSIGDKTLEFFSVPMLHWPDTIYTYIKE
                     DKTLVTCDSFGSHYSNDKIVNTLDEDEEKDYLDALRYYYDCIMGPFKPSMVTAIEKIK
                     DLDIDTVCPGHGPVLTENPRKIIDLYYNWSVNEQIKLEKEVTICYVSAHGYTKIMAEA
                     IKAYIEKNSNYKVNLFDVIEHKQEDILAKIAVSQGVLFGTPTILGDALKPIWDILISL
                     NPVLHGGKVASVFGSYGWSGEGIENAMERISQLRMTAVKPFAVNFKPSNEEIDKLHSY
                     TGKFLDKLNSTFGSKKKTKKFKCVICNEVFEGDSAPSVCPVCGAKEDQFIEVEEDEVT
                     FRKDTDEYFVIVGNGAAGFYAADAIRKRNKTCKITMISNEDELTYYRPALSDGINEEL
                     GSDFYMEDKDWYDKNNIVVILGTNVDKLDEVNKTIIVNDGAIKFDKLVIATGSRNFIP
                     PIKGHDLENVFTLRNIKDLYSVKEALEKSKKVVVIGGGLLGLEAAWEFRLKGLEVVVV
                     EAMDSILSKQLDKEGSKILEQCVRDTGIDVRLGVAVDGIEGDGKAQKVVFKDGDSVDC
                     DMVVFSIGVRANTQMVQDTSVKIDRGIVVDKTLQTNVKDIYACGDVAQVGNISLAIWP
                     SSVEMGKIAGANASGDNLTFESEVYPVSLDAMNVKVFSIGNIQNFDKEISSKDEGQRI
                     YKKLFMKDGSLVGAILINDLSCTVKLIRLISEKGDFEDIMKADIL"
     gene            10473..11174
                     /locus_tag="PC512_001681"
     CDS             10473..11174
                     /locus_tag="PC512_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanG-Cd-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HDF2441427.1"
                     /translation="MNENILIVDDEKEIADLIEVYLKNEGFTVYKFYTGKEALECIES
                     KNLDMAILDIMLPDIDGFHICQKIREKYYYPIIMLTAKIEDIDKIMGLTIGADDYITK
                     PFNPLEVVARVKTQLRRYMRYNNSYEQQSIIVNEYDIKGLIINKETHKCSLFGKEVAL
                     TPIEFSILWYLCEHQGKVVPSEELFEAVWGEKYLDNNNTVMAHIGRLREKIHEPSKNP
                     KFIKTVWGVGYTIEK"
     gene            11224..12306
                     /locus_tag="PC512_001682"
     CDS             11224..12306
                     /locus_tag="PC512_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF2441428.1"
                     /translation="MRTALMAFIAIIFIWILYSFILYGKFSIWIVSFFENAFRMEYKA
                     ALNLYQQIFRNSMELFMILAMVIVFFIIFRVYLNWFTKYFSEINQGIDSLIKEDVGEV
                     ALSPELLAIEKKINSIKHILEQRKFETQMAEQRKNELIVYLAHDLKTPLTSVIGYLTL
                     LRDESQISEELRKKYLSISLDKAERLEDLINEFFEITRFNLSNISLEYSTVSLTRMLE
                     QLTYEFKPTLMSKNLKYTLNVTPNMMIRCDVNKMQRVFDNLLRNAVYYSFEDTTIEIT
                     AVQEDDYIKLKFINHSNTIPEEKLERIFEQFYRLDTSRNSNSGRAGLGLAIAKEIVEL
                     HNGTITAHSENNIITFKVIIPIVGNL"
     gene            12567..13667
                     /gene="vanG"
                     /locus_tag="PC512_001683"
     CDS             12567..13667
                     /gene="vanG"
                     /locus_tag="PC512_001683"
                     /EC_number="6.3.2.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-serine ligase VanG"
                     /protein_id="HDF2441429.1"
                     /translation="MNNKKIAVIFGGNSTEYDVSLQSAFAVLENLNTEKYDIIPIGIT
                     REGNWYHYIGDYNNIQNNTWFERDTDIIPVIVSQNRVKNGIIEFLIPDAVSQNHIPNS
                     AIESCENDIKYTKLDFVFPVLHGKNGEDGTVQGLFELAGIQVIGCGTLSSALCMDKDK
                     SHKLVHSEGIKVPKSILLKYSDKFNVAELSKDLTYPLFIKPVRAGSSFGISKIYKKEE
                     LQVAVDLAFEHDNEVIIEENIDGFEVGCAVLGNNDLLVGRVDEIELSKGFFDYTEKYT
                     LKSSKIHMPARIDLDCEKRIQETAKIIYRTLGCSGFARVDMFLTPSGEIIFNEVNTIP
                     GFTSHSRYPNMMKGIGLSFEEILDKIIEVYIK"
     gene            13664..14470
                     /locus_tag="PC512_001684"
     CDS             13664..14470
                     /locus_tag="PC512_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HDF2441430.1"
                     /translation="MMNNILLDKNKEDKMTNTILLTKDKVYDGNLILVNAFLPVKTSE
                     DIDLIPVDTRFPSILMKREATNILQNILKSICGINEIVPVSGYRTAEEQQDIYSSSLR
                     DNGKDFTKKFVALPNHSEHQTGLAIDLGLKKEVIDFICPEFPYNGICNEFRKAALHYG
                     FIERYQCKKEEITGISQEPWHFRYVGYPHSEIINKMNLALEEYIEYIKRFSYTNCLKI
                     EDKEKIIEIFYVPIHTKEEVRISIPEQCVYQISGNNKDGFIVTFWRNRKD"
     gene            14488..16626
                     /gene="vanT"
                     /locus_tag="PC512_001685"
     CDS             14488..16626
                     /gene="vanT"
                     /locus_tag="PC512_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine racemase VanT catalytic subunit"
                     /protein_id="HDF2441431.1"
                     /translation="MIRNKSYAGLDYFRIIAALLIIAIHTSPLLSYSKMADFVLTSII
                     ARIAVPFFFMLSGFFLISTYNYNCNKLKSFLKNVLFIYGIAIVIYIPLNIYTGYFSMN
                     NLVPNIIKDIVFDGTLYHLWYLPASIIGASIAYFLVKKLGLKYSLVITIVIYVIGMFG
                     DSYYGFLEKIPLLKNLYGYIFEVSDYTRNGIFFAPVFFILGGIISNKSNYMSTKNSLI
                     GFLISFLLMLCEGMFLHKLGVQRHDSMYIMLLPCMYFLFTALTFLKGSRARLLRTSSL
                     IIYIIHPMMIVVIRMFSKIFGIQTVLVDNSLIHYIVVSIASFIASIIIILILKPLKKD
                     LKGEHKVNTNRAWIEIDLNNLEHNVKMIQKAMPEDCELMAVVKANAYGHSAFEVATCA
                     NQIGVKAFAVATIDEGIDLRRYGILGEILILGYTNPIRAKELHKYNLTQSVIDLNHAI
                     SLNKQKYNIKSHIKIDTGMHRLGFDVNDVRSILKAFKLKYLDICGIFTHLCVSDSLKD
                     EDVDFTNKQIECFYKLIDFLLKKGIKIPKVHIQSSYGFFNYPNLKCNYVRIGIALYGI
                     LSFPNDTTKLQLDLRPVLSLKSQVILIRKIQKDDSFGYGRVFIASRDSVIAILSIGYA
                     DGIPRNLSCGKSYVIINGCRAAIVGRICMDQLAVDITDIPNVEVGNTAIIIGRDNLSE
                     LSVSEVANNSCSISNELLSRVGRRLNVIKK"
     gene            16940..17560
                     /locus_tag="PC512_001686"
     CDS             16940..17560
                     /locus_tag="PC512_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HDF2441432.1"
                     /translation="MQYIQELLDLTQNYWVLATIIGLLSAFIESFIPALPLVAIVTAN
                     AAIQGLFIGCLLSWIGSGLGTTSLFLLISRFNDSKLFNKLRNSKTEKAISWMDKQGFK
                     LLFIAYACPFMPGCLVTIASAFGKKDLKDFVPAMLAGKFVMFIVISYVASDIEGFITS
                     PLKIASFILLVFLSWKIGNRVNKNLENHNYDFHHKKHHNDKDDKMI"
     gene            complement(17726..18262)
                     /locus_tag="PC512_001687"
     CDS             complement(17726..18262)
                     /locus_tag="PC512_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HDF2441433.1"
                     /translation="MIKETHERGGYIFALLILPFINNLYLVKYDIAYKIVLIIIYIYF
                     AYLGSLFPDIDMRGSYISKKFMLIYKLFGSRFRHRGFTHSLIALLLIYSFFKSLTIFT
                     NNNIVFSCLSSGFIIGYLSHLCLDLITKEGIELFYPITINISLLPIKTNSKTEKFISK
                     LLNFIVIFLIGYQFYILL"
     gene            complement(18375..19049)
                     /locus_tag="PC512_001688"
     CDS             complement(18375..19049)
                     /locus_tag="PC512_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HDF2441434.1"
                     /translation="MSLFIISQCITSFAFTPENNKFKVKPLPYAYDALEPYIDKETMK
                     LHHDKHYQAYVDKLNAALEKYPELYNYSLCELLQNLDSLPKDIATTVRNNAGGAYNHK
                     FFFDIMTPEKTIPSESLKEAIDRDFGSFEKFKQEFQKSALDVFGSGWAWLVATKDGKL
                     SIMTTPNQDSPVSKNLTPIIGLDVWEHAYYLKYQNRRNEYIDNWFNVVNWNGALENYK
                     NLKSQD"
     gene            19252..21126
                     /gene="asnB"
                     /locus_tag="PC512_001689"
     CDS             19252..21126
                     /gene="asnB"
                     /locus_tag="PC512_001689"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HDF2441435.1"
                     /translation="MDGNISIYYKGDISKKEDIKFKIKESVNNTRLSSRIEYKDEEKT
                     FDFERFNVIDAIYGNKPFEKDGKVIVFNGNIYNYHEIKEELIKKGHNFTTNDDIEVLL
                     ASYIEFGKNCVHKIKGMFNFIIYDRENESIFGARDLFGIKPLYYINKENAIIFSSEYK
                     FLLEYMKNLNINERSLQSYFSFQYVLPEDTMIQGIRLIPAGHYFRVENGILSLKRYNK
                     LEFRSSTKFFYTKNHLGNRDVNEDDIRNIVVDSIVTHMEEEKEIGTFLSGGIDSSIIT
                     TVASQINPNIKSFSAGFSVKGYSELEVAKKTADKLGIENIQINITQDEYIKSLPNVIY
                     SLDDPIADPSEVGLYFLIKEAGKHVKVALSGEGADELFGGYNIYKEYSTMKSVVNSPT
                     YIKSILGRVSELMPNIKGRNYLYRATTPLEKRYIGNAKVFENSEVKRFFFKYKEKNIY
                     EYLLSNLYRDAQKNNYDYISKMQHIDVNTWLQGDILQKISKLSTAEQVELRVPFLYKD
                     VFDVAKNLRMEQKINKNNTKVLLREAFREIVPEHVVQRKKLGFPTPIRVWLKDSLGDI
                     VKETIYNSNVDEFIDKKYAIKLLDTHLKGHRDNSRKIWTIFTFCLWHQLFIEHKNVEY
                     "
     gene            complement(21218..22654)
                     /locus_tag="PC512_001690"
     CDS             complement(21218..22654)
                     /locus_tag="PC512_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HDF2441436.1"
                     /translation="MICTIKPLKISIKKSTEPLIEFISDTTYKNKRSSYIKEVYFTRY
                     IGVDDSIDKYIEKIKNIDTYFFNNPTIPYIRLNNLKINFDKEQTDKMLKIFNIYNSSK
                     FNSWDLYNIDFPCKIENDTLNWTKKIAFKNTLDLFSTSMPNCTSSIIKNFAVKLLCWI
                     DYFLPKLFYNKVKTTISPKIVYFGNIKRQELFFLYFLSQLGCDILYINPNKDILDLYP
                     ECSKFSTLFELSRKTPNILEIPFERHITNINYSENTNKTSPTTNKPNSKNTLNNTNLT
                     SKKIVQDEEVELSYEDLAKLSASVVMIVVCNNENKPFKSGSGVVINNEGYILTNLHVV
                     NDGYSFLVRFENDDKVYTSYQIIKYHSDYDLAVIKVDRKCKPIPVKVSKKPVRGQKIV
                     AIGSPLGLFNTVSDGIISAFRDFETVQMIQFTAPISSGSSGGALLDMFGNLLGLISAG
                     YDDGQNLNLAVESNLVKIFANNFIEIVN"
     gene            22983..23561
                     /locus_tag="PC512_001691"
     CDS             22983..23561
                     /locus_tag="PC512_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_126936537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HDF2441437.1"
                     /translation="MGITLSKGQKVDLTKGNPGLKNILVGLGWDTNKYDGGFDFDLDT
                     AAFLTGASGSVTNDGDFVFYNNLKHTSGAVEHLGDNRTGEGDGDDEQIVVDLSKIPGE
                     ISKISFTVTIHDATERRQNFGQVSNSYIRIVDKDTNEELIKYELGEDFSIETAIVVAE
                     IYKHNGEWKFNALGSGFEGGLAALCGNFGINL"
     gene            23600..24178
                     /locus_tag="PC512_001692"
     CDS             23600..24178
                     /locus_tag="PC512_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_126936537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HDF2441438.1"
                     /translation="MAIVLKKGQKIDLTKGNPGLKNIKLGLGWDTNSFDSGYDYDLDV
                     SVFMVGESQRVEKDEDFIFYNNLKHPSGAVEHLGDNRTGEGDGDDEEILVNLETMPKH
                     IQKIAVTVTIYEAAERRQNFGQVSNSYIRVLNSENDEEILRYDLGEEFSIETAITVCE
                     IYKYNGEWKFSAVGAGFEGGLEALCRNYGLNV"
     gene            24264..24893
                     /locus_tag="PC512_001693"
     CDS             24264..24893
                     /locus_tag="PC512_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HDF2441439.1"
                     /translation="MSINLSKGDKIDLKKSNPGLSNILVGLGWDPVQQSGGGFFKSLF
                     GGGQADIDCDASVFMLNQEGKLSGIKDLIYFGNLKSACKSVLHTGDNLTGEGTGDDEQ
                     ILVNLDKVPSNIHKLLFVVNIYNCVDRKQHFGMIENAYIRVEDQGNKKEIAKYNLSDN
                     YSEKTTLIVGAIYRKDGSWQFKAIGEGTKDAGLKEVMQNLDRIECAYGI"
     gene            24883..27642
                     /locus_tag="PC512_001694"
     CDS             24883..27642
                     /locus_tag="PC512_001694"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HDF2441440.1"
                     /translation="MEFNNDIKYYNVDKEEVTKDLSVNPEKGLSESEVKTRREKYGLN
                     EFTPKEEGSFWDDLKESLSEPMIVILIIAAVVSAVIGETHDAIGIVGAIAIGIAIGMI
                     TEGRSKKAAEALSKLTENIEVKVLRDGEVHQISKSELVPGDIVYIETGDMVPADGRLI
                     ESINLKIREDMLTGESDDVSKKCDVVVSMEEIESKGAVVVQEPIPAKQINMVFGGTLV
                     AYGRGALVVTSIGDNSEMGKIAQNLSETDEQTPLQIKLGNLGGLIAKVSSAVAGLLFI
                     FMVFQMISKNVLNVDMSGILPFLESIDPVKTAFTVCVALIVAAVPEGLPTMINMTLAI
                     TMQKMAKINALVTKKEACETIGSVSVICSDKTGTLTENRMTVEVAYVDGRYIESSEEE
                     INSYFEENCMINSTADVEHNDGDIKYLGSATECALLLYYKNVDYRQVRKNSNIVAQNP
                     FTSDSKRMTSVIGQDNHHVLLSKGAPEVLLELCSHIQRGKDIVPLTENIKHEILEEIK
                     KLQIKSMRTLGFAYKEISQAEEEAAVTAESDAMNVSAMENNLVFSGFVGIRDPLRKDV
                     IESVNTANKAGVSVKMLTGDNINTARAIGEELGLLKNNMRVVEASYIDTLDDEELKQE
                     IQSISIVARSKPDSKMRIVSALQKSGDVVAVTGDGINDAPALSKADVGIAMGISGTEV
                     SKNAADIILTDDSFSTIVKGIKWGRGIYDNFQRFVQFQLTVNVIAFLVAIISQVMGQE
                     MPFTTIQLLWVNIIMDGPPALALGLEPVRDHVLNRKPVDRKANIISKSMVYTIVLNAF
                     YITAILMLQSTFNFLGVDEAHKGTVMFALFAFSALFNAFNCREFNADSIFPNFTHNKL
                     ALQIIVLTGIAQVIFTQLFQDFFNSVAMDFMTWVKVLCVAASVIVVNEVVKCIIRLVK
                     PKKTA"
     gene            27729..29291
                     /locus_tag="PC512_001695"
     CDS             27729..29291
                     /locus_tag="PC512_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceG family protein"
                     /protein_id="HDF2441441.1"
                     /translation="MGDSKVFEKIFSSQSDRGNYTPSKGYLSYFISYIGLEDEVLYNL
                     EIFKTKQNIDSKKDIALFTDVIANPSDFDIINYFKSGLQKYRTSMEDVDINILGFEEI
                     DYKIKQAMDRVLKEEEKEFTNDRVKQNFIVKIMAWIKIYIGALDINKNEAPKVIFYGD
                     IKKHEVYLLLILYLAGFDVLYLNPNSKSNIDILKSERYNIEFEEANIIEEKISFEERV
                     ILGEKIDKSSVKKAFTVGAEASKRISEELLNDAGFIKPWQLQDRKIKNLLLSSTVDEI
                     SIYWNQPLKLRPGFKFNDAIVEAPNFLSKINGIYNDKNEYIKFLDLLRDSESSTFIEF
                     NGDVDRFSKAFTREAFSLSFLLDSKGAIDKNSVLNNKDYSISTLALNQQIMILEKVEE
                     LLEGSMFLNGLSGEDKIKGLFTVLHMDKKFVHMMNNFDYSLINPKLIIYMYKSIVFDK
                     EIVFLMLLLSKIGFDIIILCPGGENNIENVINNQLIDVHRLDKMVYDLKLNSLENDIP
                     LLKKIFGKRRRF"
     gene            29292..30428
                     /locus_tag="PC512_001696"
     CDS             29292..30428
                     /locus_tag="PC512_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HDF2441442.1"
                     /translation="MGININSFSKDKNSVEVTENLPTAVQEENFDIMEYTNNKKNELR
                     KSKEVEALTSLIEVENPDTILQFGRKASEGVARVSDSLLNTIKLNRNEENSKMLVHLT
                     KIMDKFDLDDFQETKEPNFVQKLFKKANNAIEMMFQKYETLGGEVEKIQIELEQYERD
                     IALSNKQIGAMLNENFEFYNELQKYIVAGEMAIEEMDNEILPFFKQKSETSGDQMDVV
                     NYQELLKVYDMLNQRVYDLRIAENIAIQTIPMLRGMQHNNYGLIRKINSAFVVTLPVF
                     KQCLSQAILLKKQELQAKSLKALDDKTNELLLRNAQNVSTQSAQIARMAGTSSVQIET
                     LEKMYNTIKSGIDETMRIEENNRALIKDNTKRLEELNTTIIYNK"
     gene            30492..31568
                     /locus_tag="PC512_001697"
     CDS             30492..31568
                     /locus_tag="PC512_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HpcH/HpaI aldolase/citrate lyase family protein"
                     /protein_id="HDF2441443.1"
                     /translation="MKYFDYICKDDLERIFLKEPEDFSAKTEKDVLKYALGAFLYVPA
                     TQYNMIYKSIIGDVKGVRPLAICLEDAVGVNGELEAIENLRLILKNISNESITNKDGI
                     PLIFVRIKDVEQLLRIKEIIIKNRHSITGILIPKANSELIENCIEALDSMNLQDMYVI
                     PIIETKEFIYNEKKELSFTNLYNAILRHKSRILSIRVGITDILGMYGIRRDKNFSIYN
                     NLICSSFILDIITYLQRPELDIPISGGVSEFFDMTNKDIRNKYIEEILLDKYHGLIGK
                     TVIHPMQIQIVQALSTVSYEDFTDALDILDSTDSKYGVSKGVLGERMNETNPHFLWAK
                     KTLILSKIYGVLNKGVDYEELLKF"
     gene            31546..32784
                     /locus_tag="PC512_001698"
     CDS             31546..32784
                     /locus_tag="PC512_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyltransferase family protein"
                     /protein_id="HDF2441444.1"
                     /translation="MKNCLNFNCEIDIIDNPLNLELNDFLDVGIRNNSKRRFLFISKK
                     LGKHLACKPSEMDNLGKLMATIYNEKNKEESNGTVIAFAETGTAVGHSFFDYLCGDYE
                     FIHTTREQFDELENLEFLEEHSHATDQNLYFGMLNNFKFGDEIILVDDEITTANTCMN
                     IIRKIQSIYPKKKYTICSILNWVSDENLSKVTRLERELDCKIDFVYLFKGNFKFYIDE
                     DIISNYNDNYSITKLETISSDKVNLVVNHIYVDLEDYIGNKKYVKYTGRFGINRREQF
                     RLKEIVKRESKKITMASKESLKNEKEKILFLGTEEFMYIPMLFAKEKENQYDIYYHST
                     TRSPIINIDKNNYPIKSKFMLKSFYNIDIQNYIYNIDKHNFSKCYLFVELNKSENSYL
                     EFIDIIKKTSIKELTIVCCS"
     gene            32838..33926
                     /locus_tag="PC512_001699"
     CDS             32838..33926
                     /locus_tag="PC512_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine protease StiP family protein"
                     /protein_id="HDF2441445.1"
                     /translation="MRDFSTYSKDDVIFLLKDISNLIEEEGNKERELKIQNGRHYSEM
                     IPIEYEVSEDYLNLYHEKLRENKDKLAFSIGVMCEKIIKKNGNDVVLVSLARAGTPIG
                     ILAKRYIRSKYNVSLPHYTISIIRDKGIDMNAIEYIVKNHPSSKIQFLDGWTGKGTIS
                     KELEKACDELNVKFKKYFDSTLAVLADPAGYSGLYGIREDFLIPSACLNSTVSGLVSR
                     TVLREDLISKNDFHGAKFYRHLKDKDESMNYIETIEECFKNQFKNISDEVENWESDII
                     TRDGYFDVLNIKEKYNITDINFIKPGVGETTRVLLRRVPYKILVKDLNDKSLDHIFIL
                     AKEKNVEVEQMDLKAYKCCGIIKNMKDI"
     gene            33954..34745
                     /locus_tag="PC512_001700"
     CDS             33954..34745
                     /locus_tag="PC512_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HDF2441446.1"
                     /translation="MIVFSDLDRSIIYSNKFLNADSKYANIEIYREKEISYISLDTIN
                     LIKQIQYYGMFIPTTTRTVEQFKRIEFNKYGIYFPWSITSNGGVILKDNEILKSWSEK
                     IDKLKSDYEPIESMIHKFKDYLNVDGITNFKVAEDTFFYIVVDLSRFNLDSIKEYTNI
                     LESKNWKFYVSGRKIYFIPKEISKENAIKYLTKELGIEYFYAVGDSIMDYGMLNISNK
                     SYVLKHGDINKNEIENSFISSSFNGMSGTEEILSNILDENCLLNI"
     gene            complement(34860..35414)
                     /locus_tag="PC512_001701"
     CDS             complement(34860..35414)
                     /locus_tag="PC512_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HDF2441447.1"
                     /translation="MNIDVGSKIRSLRKSKNISISTLAKNSDLSTGLISQIERNMVVP
                     SIVAMWKISKALDINIGYFFEEIGREDSDIVVKKNNRKKIVTNDSTKFYELLVPNLSG
                     KKIEFILVTLDGHTHKNSEFVTHEGEECGYIIKGKMKITLGNKEYLLEEGDSFYFNST
                     IPHVYENYDDEVCISVWAMTPPSF"
     gene            35610..36812
                     /locus_tag="PC512_001702"
     CDS             35610..36812
                     /locus_tag="PC512_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 domain-containing protein"
                     /protein_id="HDF2441448.1"
                     /translation="MKSFVSPDNIWVLWAVVTGWAAFSIYLEQKYNWASKVSGAIIAL
                     VGAMLLSNLNIIPVESVVYDQVWGYVVPLAIALLLYQCNIKKIWKESGRLLIIFLVGS
                     VGTVLGAMIGFLALKNVVPDLNIVAAMMTGSYIGGNVNFAAMSGAFDAPGELVSATVV
                     ADNLLMALYFFVLIAIPSIGFFRKHFKHPHVDEMESIGITEGETVAANYWGRKEISLK
                     DIAIAIGSAFIIVAVSVELSTWFKAIIPLSNPFLAMLNTLFGNQYLIITTLTMLFATF
                     MPNFFGDIKGAQELGTFLIYIFFVVVGVPASITLIIQKSPLLLLYCGIMVLINMLVTF
                     IVAKIFKFSLEEAILASNANIGGPTTAAAMAISKGWSKLVGPILIVGTFGYIVGNYFG
                     LLVGNILI"
     gene            36869..37849
                     /locus_tag="PC512_001703"
     CDS             36869..37849
                     /locus_tag="PC512_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HDF2441449.1"
                     /translation="MIFDGHSDTWADVTIRRLNGEKDVFRRIHLDNFKRANIEGAIFV
                     IWIDPPYDKEPEKRVKQIISSIKDEIEDMKDVVNIVKKYSDIDKGISENKINILIGLE
                     GLSHIGRNIDLLDYFYKEVGARHASLTWNEQNELATGCLGDENRGLTEIGKKAVNKME
                     KLGMIVDVSHLNEKSFWDLMSVASKPVIASHSNARSLCDAKRNLTDNQLKEISNTGGL
                     VGINSFRGFTNSNPKKQDLIHLVDHIDYMVNLIGIEHVSFGFDFSDYLGKETIGSFTG
                     NASVPSVDGLESTHTAQNIVVELENRGYKKKDIELISSGNFYRLFKDILK"
     gene            38097..39050
                     /locus_tag="PC512_001704"
     CDS             38097..39050
                     /locus_tag="PC512_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HDF2441450.1"
                     /translation="MKKRYLVIGIIILSYFSLFIGAEDINIMHIFAKNQHKLMIFIMS
                     RIPRLISILIAGVGMSIAGLIMQQISKNKFVSPTTGATIDAAQFGIVICMLLVPTASI
                     FTKTIIAFVFSLVGTFTFMKIIGKLQFKNIIFVPLVGIMFGNIIGSMTDFIAYKYDLS
                     QNVSSWMQGDFSMILKGNYEILYITIPLIILAYIYANKFTVVGMGMDFATNLGLSYKR
                     IVNIGLIIVALVTVCVVVTAGNIPFIGLIVPNIVSLYMGDNIRASIWYTGLLGAIFVL
                     ICDIFGRIIIYPYEISIGLTVGVIGSILFLYLILRRNVNEA"
     gene            39040..39996
                     /locus_tag="PC512_001705"
     CDS             39040..39996
                     /locus_tag="PC512_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HDF2441451.1"
                     /translation="MKLSLNQKIYFVSILLFISIALFIIYGIDMNHLEYALSQRIPKI
                     FAMVLGGGCIAFTTVVFQTITNNQILTPSVLGLDSLYVMIQTIIVFIFGSSSSLIINE
                     NYNFIINVAMMIGASLLLYKTLFEKNKNNIFFLILVGMIFGTLFKSATTFIQVMIDPN
                     EFLALQTSIMASLNNINTNVLLIAFIIIIAIIPFIYDEIKYLDVLSLGKEQAINLGVD
                     FDKAVKKMIILIAILVSISTALIGPMTFLGLLLANITREIFKTYKHTYLISGSMLIGM
                     ITLIIGQFFIQHVFKFDTTLSVVINFIGGIYFIQLLLKGANR"
     gene            39993..40748
                     /locus_tag="PC512_001706"
     CDS             39993..40748
                     /locus_tag="PC512_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2441452.1"
                     /translation="MIEIKNIFKRYKNKNVVDDVSFSIEKGKITSFIGPNGAGKSTVL
                     SIVTRLIGGDGGEVIIEGKSLTNYSNKELAKKIAILKQSNNITLKLTIRELVGFGRFP
                     YSEGNLTKEDENYIDEAIEYMKLTDIQHKYLDELSGGQRQRAYIAMVIAQDTEYILLD
                     EPLNNLDMNHSVQMMKVLRSLCDELDKTIVLVMHDINFASCYSDNIVALKNGKVKKVG
                     RTDEIVNEKVLEDIYEMNFNIKNINGNRICIYF"
     gene            40840..41805
                     /locus_tag="PC512_001707"
     CDS             40840..41805
                     /locus_tag="PC512_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF2441453.1"
                     /translation="MNKKAAIVAAVAIIGLVTVFALGGSKKNESKTSENSNNTMKITH
                     NLGETDVKLNPKKVVVFDYSALDTMDALGVAENLVGLPKASLPASLEKYKDDKYADLG
                     GLKEPDLEGIKSANPDLIIINGRQEDFYEQLSKIAPTISTSKDDKKYLESVKNNIDKI
                     AKIFGVEEKANQEFSKIEKKIETLNKKVTDKNLNALTIMVNEGNLSVFGEESRFSILY
                     NSFGFENKDKNIKESSHGQNITFEYIAKQNPEVMFVIDRGIATGSDVKESSTAKSVLN
                     NDIIKSMDAYKNDNIIYLDSPTWYVNDGGLTSLNKMIDDASKAVN"
BASE COUNT        16319 a         4322 c         7232 g        14061 t
ORIGIN      
        1 gaaaagaaaa tattaaaatt ataatataaa aataaaattt ttcagacaat ttaaacaaaa
       61 ataatcacct tttaataaat aattatatgc caaaataatc caatttattt tctattatac
      121 ctatatgaaa tatataaatc aatagttaag acaatgaata tactacattc tataattata
      181 gtagcagaaa attttacaaa attaaagtag atataaacta tccattttac aagaaatgga
      241 aacttttgag atgtacttat ttgctaataa aatagaggtg ttttaatggg aggaaatttt
      301 tatgaggaat ttacaaaaaa aattgatgtt ttttttattt atttgtataa ttttacaaat
      361 tacatacaca acaccagtct attctttatg caaactctat aaaaacaact ccataaataa
      421 ctttgagtct attgtgtcta ataatcagct tattagcaaa catgcaatac aaataatact
      481 tattatggct ataatatgtg taatacttat attctatata atatatgata aattaaattt
      541 taaaattaaa ttgcaaagga tagcatatac agataatctt acaggagcaa atactataga
      601 taaatttgta attgatgcta acaaaatact atgtaaaaat actcaagtaa agtatgcttt
      661 attatatata gatattgata aatttaaata tataaatgat ttatttggat atgaagttgg
      721 gaatgaaatt ttgcgtaatt taacaaagat tattaagagg aatatatttg aagaggaaat
      781 gtttgcaaga atatctgcgg ataattttat tataattatg aaatatatag aagaagaaga
      841 tataacaaag aggttaaaaa ctatatttga agaattagac ttgtttaata ataatcaaga
      901 agaaaaatat aagttagttt taagttgtgg aatctatttt atacttccag aagatagaga
      961 tatcaactca atcatagata gggctaatat acctcataaa atggcaaagg gaggacataa
     1021 aagttcatat gcattttatg ataataagat tcatgaccaa gagataaaag aaaaagagat
     1081 ggaaaataca atgttttcaa gtctagaaaa taaagaattt attatatact tacaacctaa
     1141 gatagaactt aatacaggag agatacaagg ttcagaagca cttgttaggt ggaaacgtcc
     1201 tgataaaggg ctaatacctc caaatgaatt tatcccattt tttgaaagaa acggttttgt
     1261 tataaattta gatttatatg tgcttgaaga agtatgtata taccttagaa aatggattga
     1321 tgcaggaata aatccagtta ctgtttcagt taatgtttca aggatacatt tatattgcaa
     1381 taattttata gaaacataca aaaatataat tgataaatac aatatacctg caaagtatat
     1441 agaacttgaa ttaacggaga gtatcatatt tgataatttt gatattttaa ttgatataat
     1501 gaataattta aaaaaaatag gatttttaat atctatggat gattttggct cagggtactc
     1561 atcattaaat atgttaaaag aaattcctat ggatatctta aaacttgacc aaaaatttat
     1621 tatggaaact tataatagta aaagaagcaa aataattgtt actaaagtaa tagaaatggc
     1681 aaaagagttg ggtatgaaag tcatatcaga aggagttgag acagaagaac agtttaaact
     1741 tttaaaagaa gtaaagtgtg atatggcaca aggatatttg tttggaaagc caatgccaat
     1801 tgaagaattt gaacatttaa ttgtatctaa cttggtaaga gggtaattaa tctgtaatat
     1861 aaagaattta ataaattgtg ttaaaaatgg actctaatgt agtgttcatt ttttttgtaa
     1921 aattttttat acttttacta aaaagtaatt gacatatact ttgtattatt atattattgt
     1981 attaacaact taatacaata atataataag gaggcatgaa catggaatgg gaacttgata
     2041 ataacaaacc tatatatata caattagtag aacatttaaa gttaaaaata atttcagggg
     2101 aaattaaaat aggatctaaa ttagaaacag tgagagcact agcagaagat gcggaagtta
     2161 atccaaatac aatgcaaaag gctctaacag aacttgaaag acaaggttta gtttatagtc
     2221 agagaactaa aggaagattt gtaacagatg ataaggaaaa aataaaagct atgaaagagg
     2281 aaatagctaa tgtggagata aatacattaa aagtaacctt agaaaagctt ggatatgata
     2341 gagatgaaat gctaaaactt attacagaaa atctgaaagg agaattataa aatggataaa
     2401 aatataagca atgtttctca agatggaata gttgaattta aaggtgtaaa caagagttat
     2461 ggaactaaga atgttttaaa aaatattgat ttaaatatac caaagggaaa aatagtcggg
     2521 ctgttaggac ctaatggaag tggcaaaagt acaatgatta agctaatgaa tggattatta
     2581 cagcctgata atggtgaaat tatgataaat ggaatgaaac catccataga tactaaaaaa
     2641 atagtttcat atttaccaga aagaacttat ttaaatgatt ggatgaaggt atcagattta
     2701 cttaagtttt tctatgattt ttatagtgat tttgatgtta gaagagcaaa tgagatgatt
     2761 aaaagcttag atattgatgt aaatgaaaag ctaaagacaa tgtctaaagg aactaaagaa
     2821 aaagttcaac ttattttagt aatgtcaaga aatgcgagca tatatatatt ggatgaacct
     2881 ataggtggtg ttgacccagc tgcaaggtca tatatactta agactatatt aaaaaattat
     2941 tctgaagata gtactttact gattgctacc catttaataa gtgaaataga aaacatatgt
     3001 gatgagataa tattcatatc aaaaggagaa atagtgttac aaggagacgt tgaagcaata
     3061 agagaagaaa aaggaaaatc tatagatgca ttatttaggg aggaatttaa atgttaggta
     3121 aattattaaa atatgagtta aaagcaagtg gaagaatatt tataccgtta tatatagcca
     3181 tattgatagt agctgtattt aacggaatat ttatgaatac aaatatactt caggtacagg
     3241 gaataggaat actagtatta acaagtcttt ttatggcatt aggagtttta actattgtag
     3301 ttacaattca aaggtttaga aaaaatcttt tgggggatga aggttattta atgtttactc
     3361 ttcctgttag cactagttca cttatattat ctaaatgtat aacagcactt atatacgctg
     3421 tacttagttt tatagttgca gtattcactt ttggagttct tatgcttttt ggtacttctg
     3481 gaattttact acctgaaatt ttagatttgt ttaacactag ttttaaatgg atttctgaaa
     3541 actttttaga tattttatta ttagtagtag taatgtttat ttcatattca tcatttattt
     3601 tgttattata tacatcaatc tcaatgggac aattaccaaa attcaataaa catagaaaca
     3661 tagtggcatt tgcttctttt atagctataa atatagtaat atcaattgtt ggagatgcag
     3721 ttggaagcat cttaccaaat gaagatacaa atatggtata tcatctttat cagagtccta
     3781 gttttatgct tgcaatactt ggtagtcttg tagttgcaat agcgttattt ttcgctacaa
     3841 aatttatatt agataaaaaa ttaaatttag aataaatgtt tttatatgga gccatctttt
     3901 gagtaatgtt aaaagatggc tcttattatt tatgtagtta attcatgtat ataatatgaa
     3961 tagtgtttta tttctagtta aatatataca tatgttgtat aatgatattg cgtgtaaaaa
     4021 tttgtaagaa taactataca ctttatataa gttatatcaa gaaaatttaa aaatatatgg
     4081 atttgaggga gaagatatga aaagttatac aaaggctaag tggagtgttt ggggtataat
     4141 tacattttca tttgttttag tattattttt aaggatgtca actgctgttg tttcagacaa
     4201 tttagcaaat gagttaggtt ttaattctat acaaatttca aatatagcat ccttttgcct
     4261 atatgcatat gcatttatgc aaatacctgc aggaattttg attgataaat atggagcaag
     4321 aaaaattagc agtcttggaa taataatggc aagtttaggg tcaattttat ttggtttgat
     4381 tcaaagtata gaattagcat atatttctcg tgtaattgta ggggcaggaa catcagtaat
     4441 attactttgt attttaaaaa ttcaagggag atggtttaat aagtcagaat ttgcttctgc
     4501 aacagctaaa ttttcatttg taggaaattt aggtggagtt cttgctactt ttccacttgt
     4561 gtttttgtct gaacttgttg gttggagaaa ttcattttta ttaatcggta taattggtgt
     4621 tgtaattgga tgttttatgt atattattgt tagagataca ccaaaagagt atggattcaa
     4681 tatagatact gaaccctatg aaaagtcaga gaaggttaat attgttgatg gtattaagtc
     4741 tgttataaag aacaaatcaa catggtataa ttcaatgata atgttctctt ttgtgggtct
     4801 tacaagtgca tttataagct tgtggggagt aagatacata atggacgttt atggtgtgag
     4861 taagagtttt tctgcgttta tagtatcatt ttttacatat ggatttatat ttggttcaat
     4921 aattatggat tttgtatttg ctaaaataag gtctagcaaa tttaatataa taaaatttgg
     4981 ggcaatgata gatttgttta tatggattgt aattgtagtt gtataccagg taaaaccacc
     5041 aattatagtt ttaccaatat cattctttat tatgggatgt atagttatgt cacatctaca
     5101 ggtttttaat gatgccaagt ataaaaataa agaaatttat tctggactgg caactagtgt
     5161 tattaatact tttgaattta taggaagtgg aattattaat ttgattatag ctatctcttt
     5221 acaagtaaat tcatataata tagttgatgg atataaaaaa ggttttgtag tatttatagt
     5281 actaagtatt ataactatag tatcatctca tataggggta aaaaatgatg attttaaggc
     5341 tatatagtgt tttattaata gtttaattta gtattatatt ttgcatatat atataacaaa
     5401 tagtttgcat tttcctaaga tgtataattg gaatataaat cttgtttact atgtacaaat
     5461 ggtattgtat tatattaaat agaaaataag aactttaaac tataatattg gttctaaaat
     5521 ataaggtaag gagtttttta tggatacgac gaaaatagat gatataagca agttagattt
     5581 aaataattta gatattaata agatggatat gggaggtata atggaaagtc tattagaatg
     5641 ggctactaca agcggagtaa aacttataat aggcatactt atactttcta ttggatttaa
     5701 aataataaaa aaatttgtaa accatgttat gttattactt agtaaaagag atattgattt
     5761 aactttaaga aggtttttga agtctcttct tttgagtgta cttaaagttg ccgttataat
     5821 cattgttctg gaatattggg gaatgagttt gtccagtttt gctgctgtga tagcatcagc
     5881 aggggtagca ataggtttgg ctttacaagg tagtctatca aattttgctg gaggatttat
     5941 tatactattg attagacctt ttaaagtagg agattacgta gaagcagcag gccatggagg
     6001 aacggttgaa caaataggac ttttttatac acaattggtt actccagata ataaacagat
     6061 acttatacct aatggttctg tatcaaatga tagtctaata aactattcag caaagaatac
     6121 tagacgagtt gatttgactt ttagtgtagg gtatgaagat gatatactac atgttagaag
     6181 agtacttaaa gatattgtta ataatcataa attaataata aatgaaccag aaccatttat
     6241 aggagtagta gaacatggag ataatgctat taaatttgca actagagttt ggtgcaagac
     6301 agaagattat tggacaattt atcttgattt actagaagag gttaaagtta ggtttgacga
     6361 agaaggaatt acgattccat atcctaaaat ggatttaacg gtaaaagaat taaataaaat
     6421 ttaatttttt tatgtagtgt ttaaatttaa gaatattata tagatatatt tataagattt
     6481 gtgaaaaatt aataagtcct gttattttgt aagtgaaaat ataaaaaatg ggagtgtctc
     6541 aaaatgaact ttttagttca tgaggcactc tttttgtatg aaatcaaata tatttttatt
     6601 atttcaacaa taaaaaagag gtctgtttct attttgagac aatattattt ttatgtagat
     6661 ttaatcttaa tgagtataaa gttttaaaac tactaaaata ggaggaattt taatataaaa
     6721 gggtaaataa agggtttaga gggcataata tagaataaat taattattta aggagggttt
     6781 ttatgtgcaa aaaaatgtat ttattagtgg taggtatact tatagcaggt ttattaactg
     6841 catgtaatgg gagtccaact aaggattcag aacaagcaca agataataca aaaaaggagg
     6901 caaatgtatc aaataacgct ttaaaagatg aaaaaaataa tgaaaattta atggaacaag
     6961 attttaaagt gccatacaca gatgcaataa acatatttaa agacaaatac aaagatgctg
     7021 atatagtaga tttaagtctt gagagagatt taaataaatt tgtttatact gtggaaggtg
     7081 tagatgataa taatgaatat aagatgaaaa ttgatgctaa tacaaaagat gtattagaag
     7141 ataaaacaga aaagttggat tcagaagatt taaatggagt cgctagaaaa gaaaaattag
     7201 attttaatga cataatgaca cctcaacaag ctatggaaat tgcattaaaa gaacaaaatg
     7261 gaatggttaa agagtggagt ttagataaag atttagatgt tactttttat aaaataagaa
     7321 tagataaaga taaaaatgaa tatgacataa aagtagattc taaaaaggga actgtattga
     7381 aggtagaaaa agaagattag aagatttaaa ctatctttaa aataatttct tttttgaata
     7441 aaatttgttt aaaatataac aagtagggta taaagagact aaataactat tttaggagga
     7501 gtacggtatg tcattgaaat cgctaaaaat aaaagaaaat ttatattggg taggttcgct
     7561 tgaccctgat ttaagagtat ttgacataat tatgtataca ccttatggaa ctacttataa
     7621 ttcatatgta ttaaaaggaa cagaaaaaac agttttattt gagacagtta aagataagca
     7681 ttttgacaat tatattgaaa gattaaatga tttaaatata gattttgaaa aaatagacta
     7741 tattgttgta agtcatactg aaccagacca tgcaggaagc gttgaaaagc ttttggattt
     7801 agctaaaaat gcaaaagtag tagcttcaga aacagcaatt aaatatctta aggaaatcgt
     7861 aaacaaagac tttgaatatg ttgcagttac agatggagat acattatcaa ttggggacaa
     7921 aactttagaa tttttctctg tacctatgct tcattggcca gataccatat acacatatat
     7981 aaaagaggat aaaactcttg taacatgtga ttcatttggt agtcactata gtaatgataa
     8041 gatagtaaat acacttgatg aagatgaaga aaaggattac ttggatgctt tgagatacta
     8101 ttatgattgt ataatgggac catttaaacc atctatggta actgccatag aaaagataaa
     8161 agatttagat atagatactg tatgtccagg tcatggtcca gtattaactg aaaatcctag
     8221 aaaaattata gacctttatt acaactggag tgtaaatgaa caaataaagt tagaaaaaga
     8281 agttacaatt tgttatgttt ctgcacatgg atatacaaag attatggcag aagctataaa
     8341 agcatatatt gaaaaaaata gcaactataa agtaaattta tttgatgtaa tagagcataa
     8401 gcaagaagat attttggcaa aaatagcagt atcacaaggt gtattatttg gaacaccaac
     8461 aatattagga gatgcgttaa agcctatatg ggatatatta atatcgttaa acccagttct
     8521 tcatggtgga aaagttgctt cagtatttgg ttcatatgga tggagtggag aaggtataga
     8581 aaatgctatg gagagaataa gtcagcttag aatgacagca gtaaaacctt ttgctgttaa
     8641 ctttaaacca tcaaatgaag agattgataa attacattct tatacaggta aattcctaga
     8701 taagttaaat tctacttttg gaagtaaaaa gaaaactaag aaatttaaat gtgtaatttg
     8761 taatgaagtt tttgaaggtg atagtgctcc tagtgtatgc cctgtatgtg gagctaagga
     8821 agaccaattt atagaagttg aagaagatga agttactttt agaaaagata ctgatgaata
     8881 tttcgtaata gtaggaaatg gagcagctgg tttttatgca gcagatgcta taagaaaaag
     8941 aaataaaact tgtaagataa ctatgatttc taatgaagat gagttgactt actatagacc
     9001 tgcactttct gatggtataa atgaagaact tggttcagat ttctacatgg aagataaaga
     9061 ttggtatgat aaaaataata tagtagtaat attaggaacg aatgtagata aattagatga
     9121 agtgaataaa actattatag tgaatgatgg agctattaaa tttgataagc ttgtaatagc
     9181 tacaggaagt agaaacttta taccaccaat taagggtcat gatttagaaa atgtgtttac
     9241 tcttagaaat ataaaagatt tatatagtgt aaaagaagca ctagaaaaat ctaagaaagt
     9301 tgtagtgatt ggtggcggtt tattgggact tgaagctgca tgggaattta gactaaaagg
     9361 attagaagta gtagtagttg aagccatgga tagcatacta tcaaaacaac ttgataaaga
     9421 aggcagtaaa atattagaac aatgtgtaag agatacagga atagatgtaa gattgggtgt
     9481 agcagttgat ggtattgaag gtgatggaaa agctcaaaaa gttgtattta aagatggaga
     9541 tagtgttgac tgtgatatgg tagtattttc aattggtgta agagcaaaca ctcaaatggt
     9601 tcaggataca tctgtaaaaa ttgacagagg tattgttgta gataagacat tacagacaaa
     9661 tgttaaagat atatatgctt gtggagatgt tgcacaagtg ggaaatatta gtttagcaat
     9721 atggccatct tcagtagaaa tgggaaaaat agcaggggca aatgcaagtg gagataattt
     9781 gacatttgaa agtgaagtat atccagtttc attagatgca atgaatgtaa aagtatttag
     9841 tattggtaat atacaaaatt ttgataaaga aatttcatca aaagatgaag gtcaaagaat
     9901 atataaaaaa ttatttatga aagatggttc attagttgga gctatactta taaatgattt
     9961 aagctgtact gttaaattga taagattaat atctgaaaaa ggtgattttg aggatattat
    10021 gaaggctgat atactataat ttaaatacat taaaataaaa aggagttgtc ttaaaattga
    10081 tttttttcta atcaaatttt aaattcaact ccttttttga atttttatat aaaataacat
    10141 ggaaatttta gtaatgtctg tggttacata cataggttta attgtttttt atatggattg
    10201 tctctggtat aataaattga attgtgtttg actgatagat atttttattg aaagttaata
    10261 cctgttatgc gataataagg acgtgttagg ggagttttta taataacaat taatctcagt
    10321 ttttgtgttc caatagtagc atcaacacat tctgatgtag tagttctttt cttataaaaa
    10381 ttagttacaa atatgcttgt aattatttga tatgtaaatt taccaatatt ataaatgatg
    10441 acctcgataa taaggagagt gaaaaataat ctatgaacga aaatattttg attgtggatg
    10501 atgaaaaaga aatagcagat ttaattgaag tatatttaaa aaatgaaggt tttacagtat
    10561 acaagtttta tacaggtaag gaagctctag aatgtattga atctaaaaat ttggatatgg
    10621 ctattttaga tattatgctt cctgatattg atggatttca tatttgccag aaaattcgag
    10681 aaaaatacta ttatcctatc attatgttaa cagctaaaat tgaagatata gacaagataa
    10741 tgggtttaac cataggtgct gatgattata taacaaagcc atttaaccct ttggaagttg
    10801 ttgcaagagt aaagacacaa ttaagaagat atatgcgata taataattct tatgaacaac
    10861 agtcgataat tgttaatgag tatgatatta aaggattgat tatcaataaa gaaacacata
    10921 aatgtagttt atttgggaaa gaagtagcat taacaccgat tgaattttct attctttggt
    10981 atttatgtga acatcaagga aaagtggttc cttctgaaga attgtttgaa gctgtatggg
    11041 gagaaaaata tcttgataat aataacacag ttatggctca tatagggcga ttacgtgaaa
    11101 aaattcatga accttctaaa aacccgaaat ttataaaaac tgtatgggga gtaggttata
    11161 caattgaaaa gtaaaaatat taaagtcaat cctgacttta ctcaagtgag aaataaaatt
    11221 tttatgagaa cagctttaat ggcatttata gccattattt tcatatggat tttatattct
    11281 tttatattgt atggtaagtt ttctatctgg atagtatcat tctttgaaaa tgcttttcgt
    11341 atggaatata aagctgcatt gaatttatat cagcagattt tccgtaatag tatggagctc
    11401 ttcatgatac tagctatggt gattgtgttt tttataatat tccgtgttta tttaaattgg
    11461 tttacaaaat attttagtga aataaatcaa ggtattgact ctcttatcaa agaagatgtt
    11521 ggagaagtgg ctttatctcc agagttattg gcaatagaaa agaaaataaa ctcaattaaa
    11581 catatacttg aacaacgtaa atttgagaca caaatggcag aacaacgtaa gaatgaactt
    11641 attgtttatc ttgcacatga tttaaaaaca ccacttacat cagttatagg gtatctgaca
    11701 ctacttcgag atgaaagtca gatttctgaa gaactgcgaa aaaaatattt atctatttcg
    11761 ttggataagg cagagcgtct tgaagattta attaatgaat tctttgaaat tacaaggttt
    11821 aatttatcaa atatatcact tgaatacagt acagtaagct taactcgtat gcttgaacaa
    11881 ctaacatatg agtttaaacc tactttgatg agtaagaatt taaaatatac actgaatgtt
    11941 acaccaaata tgatgataag gtgtgatgtt aataaaatgc aacgtgtatt tgataactta
    12001 ttacgaaatg ctgtttatta tagttttgaa gatactacta ttgaaataac agctgtacag
    12061 gaggatgatt atataaagct taaatttata aatcatagca atacgattcc agaggaaaaa
    12121 cttgagcgta tttttgaaca attttacagg ttggatacat ctcgtaattc aaacagtggt
    12181 agagctgggt tgggacttgc tatagctaaa gaaatagtgg agcttcataa cgggacaata
    12241 acagctcata gcgagaacaa tataattacc tttaaggtta ttattccgat tgtaggaaat
    12301 ttgtaagaat ttaagtataa aaaaatagga aattctttag gataaataaa taaagagcac
    12361 tcttgttatt gatataatta ctgtatcaaa acaagagtgc ttttattttg atacagtaat
    12421 tatatcaata gaaaaatgtg aaaatatatt atgtggaaca gatgcaattg taagtgaagg
    12481 ttgattggat ttgaaataga aaaagtattt taacatgttt ctgtagattg tataaaaata
    12541 aataaatcaa caaaggagaa tcaaagatga ataataaaaa aattgcagtt atatttggtg
    12601 gaaactcaac agaatatgat gtatcattac aatcagcttt tgcagtactt gagaatttga
    12661 atacggaaaa atatgatatt ataccaattg gaattacaag ggagggtaat tggtatcatt
    12721 atattggaga ttataataat atccagaata acacttggtt tgaaagggat actgatataa
    12781 ttccagttat tgtttcgcag aaccgtgtca aaaatggtat tattgaattt ttaattcctg
    12841 atgctgtttc tcagaatcat attccaaata gtgctattga atcatgtgaa aatgatatta
    12901 aatacactaa acttgatttt gtgtttcctg tactgcatgg aaaaaatgga gaagatggaa
    12961 cagtgcaggg gttatttgaa ttggcaggta tacaggttat tggatgtggt actctttctt
    13021 cagcattatg tatggacaaa gacaaatcac ataaacttgt tcattcagaa ggtattaaag
    13081 taccaaaatc aatattacta aaatactcag ataaatttaa tgtggctgaa ctgtcaaaag
    13141 acttaactta tccattattt ataaaacctg tgcgtgcagg ttcatcattt ggtattagta
    13201 aaatttataa aaaagaagag ttacaagtag cagtagactt ggcttttgaa catgataatg
    13261 aagtaataat tgaggaaaat attgatggtt ttgaggtagg gtgtgcagtt ttaggaaaca
    13321 atgacttact tgttggaaga gtagatgaaa tagaattgtc aaaaggattt tttgattata
    13381 cagaaaaata tacattgaaa agttcaaaaa ttcatatgcc agctagaatt gatttggatt
    13441 gtgagaaaag aatacaagag acagcaaaaa ttatttatag aactcttgga tgttctggat
    13501 ttgctagagt agatatgttt ttaactccat ctggtgaaat tatttttaat gaagtcaata
    13561 caattcctgg ctttacttct catagtcgtt atccaaatat gatgaaaggt attggactgt
    13621 cttttgaaga aatattggac aagataattg aggtgtacat aaaatgatga ataatatttt
    13681 attagataaa aataaagaag ataaaatgac aaatactatc ttattgacta aagataaagt
    13741 ttatgatggg aatctaattc tagtaaatgc ttttttacca gttaaaacat ctgaagatat
    13801 agatttaatt cctgtagata caaggtttcc aagtattctt atgaaacgtg aagctacaaa
    13861 cattttacaa aatattttaa aaagtatatg tggaataaat gaaatagtac ctgtaagtgg
    13921 atatcgtact gcagaggaac aacaagatat atattcaagt tctctgcgtg acaatggaaa
    13981 agactttact aaaaagtttg tagcacttcc aaatcacagt gaacatcaga cagggcttgc
    14041 tattgattta gggttaaaga aagaagttat agattttatc tgccctgaat ttccttataa
    14101 tggtatttgt aatgagtttc gtaaggcagc actacattat ggttttatag agcgttatca
    14161 gtgtaaaaaa gaagaaataa caggaatatc tcaagaacca tggcattttc gttatgtggg
    14221 atatccgcat tctgagatta tcaataaaat gaatctcgct cttgaagaat atatagaata
    14281 tattaagaga ttttcgtata caaattgttt aaaaatagaa gataaagaaa aaattataga
    14341 aatcttttat gtgcctattc atactaaaga agaagtgaga atctctatac ctgaacaatg
    14401 tgtatatcaa atatcgggta acaataagga tggttttatt gtgacatttt ggagaaatag
    14461 aaaggactaa gaaatggagg aacaagaatg attaggaata aatcttatgc agggcttgat
    14521 tattttagga ttatagctgc attacttata attgcaattc atacatctcc attattatca
    14581 tatagtaaaa tggctgactt tgtgttaact agtataattg ctcgtattgc tgtgccattc
    14641 ttttttatgc tatcaggctt ttttctaatt tcaacatata attataattg taataaactg
    14701 aaatcttttc taaaaaatgt attatttatt tacgggatag ctattgtaat ttatattccc
    14761 ttaaatattt acactggata tttttccatg aataatttag tgcccaatat tattaaggac
    14821 attgtatttg atgggacttt atatcattta tggtatcttc ctgcatcaat tattggtgca
    14881 agtattgcat actttcttgt aaaaaaacta ggtttaaagt actcactagt aatcactatt
    14941 gttatttatg taattggtat gtttggtgat agttattatg gttttttaga aaaaatacca
    15001 ctattaaaga atttatatgg gtatattttt gaagtatcag attatacacg aaatggtata
    15061 ttttttgcac ctgtattttt catacttggt ggaataatat ctaataaatc taattatatg
    15121 tcaactaaaa atagcttgat tggatttctt atatcattct tacttatgtt atgtgaggga
    15181 atgtttttac ataaactagg ggtacagcgt catgatagca tgtatattat gttattgcca
    15241 tgtatgtatt tcttatttac agccttaaca tttttgaaag gttctcgagc taggttattg
    15301 cgaacatcat cattaattat ttatattata catcctatga tgattgttgt tattcgtatg
    15361 ttttctaaaa tattcggaat acaaactgtc ttggttgaca atagccttat tcattatata
    15421 gtggtaagta tagcatcttt tatagcttct ataattatta tattgattct taaacctcta
    15481 aaaaaagact tgaaaggaga acataaggta aataccaata gagcttggat tgaaattgat
    15541 ttaaataatt tggaacataa tgtaaagatg atacaaaaag ctatgccaga agattgtgaa
    15601 ttgatggcag ttgtaaaagc taatgcctat ggtcatagtg cttttgaagt agcgacttgt
    15661 gcaaaccaaa taggtgtaaa agcatttgca gtagcaacaa tagatgaggg gattgattta
    15721 cgtcgatatg gaatactagg agaaatattg attcttggat atactaaccc aataagggca
    15781 aaggaacttc ataaatacaa tcttacacag agtgttattg accttaatca tgctatctct
    15841 ttaaacaaac agaaatacaa cataaaatca cacattaaaa ttgatacagg tatgcacaga
    15901 ctgggttttg atgttaatga tgtgaggtca attttaaagg catttaaatt aaaatactta
    15961 gatatatgtg gcatatttac acacttgtgt gtttcagata gtctgaaaga tgaagatgta
    16021 gactttacaa ataaacaaat tgaatgtttt tataagttaa ttgattttct gttaaaaaaa
    16081 ggtataaaaa ttcctaaagt acatattcaa agtagttatg gtttttttaa ttatcccaat
    16141 cttaagtgta attatgtaag aattggaatt gcattatacg ggatattaag ttttccaaat
    16201 gatacgacta aattgcaact tgatttacga cctgttttat ccttaaaatc acaagtaatt
    16261 cttattagaa aaatacaaaa agatgatagt tttggatatg gaagagtctt tattgcaagc
    16321 agagatagcg taattgctat attatctatt ggctatgccg atggtatacc tagaaattta
    16381 tcctgtggaa aaagttacgt aataataaat ggttgtagag cagcaatagt gggtcgaatt
    16441 tgcatggacc aacttgctgt tgatattaca gatataccta atgtagaagt tggtaatacg
    16501 gcaataataa taggaagaga taatttatct gaattatctg tttctgaagt tgcaaataac
    16561 tcatgtagta tatcgaatga attattgagc agagtaggaa gaaggttaaa tgttataaag
    16621 aagtaactca attaaatagt aatatttgtt gtactgtgta atttatttta ctctgactag
    16681 acatttttag taatattatg tctaatatat attttttata acttacatga caatttaagt
    16741 tataaaaagg tgatgtttca gatttttatt ttgaaacatc accttttttg ttataatata
    16801 taataaaata attatacctt aactgtaaac ttatatagat tatttacttt ttaatattag
    16861 attcattttt tgagattggt atataataaa catatagagt atataataat agttaaagtt
    16921 aaaaaagggg aaaagcaata tgcagtatat acaagaacta cttgatttga ctcaaaatta
    16981 ttgggtgtta gccacaataa tcggcttatt aagtgcattt atagaaagct ttataccagc
    17041 cttaccactt gttgctatag ttacagcaaa tgctgcaata caaggattat ttattggatg
    17101 tttgttatca tggattggct caggacttgg gacaacttca ttattcttat taataagcag
    17161 atttaatgat agtaagcttt ttaataagtt gagaaatagt aaaactgaaa aagcaataag
    17221 ttggatggat aaacagggat ttaagttatt atttatagcg tatgcctgtc catttatgcc
    17281 cggttgttta gttactatcg catcagcttt tggtaaaaaa gatttaaaag attttgtgcc
    17341 agcaatgttg gcaggaaaat ttgtaatgtt tatagttata agttacgtgg caagtgatat
    17401 agaaggtttt ataacaagtc ctttaaagat agcatcattt atattattgg tgtttttgtc
    17461 atggaagatt ggaaatagag taaataaaaa tcttgaaaat cataattatg atttccatca
    17521 taaaaaacat cacaatgata aagatgataa aatgatttag cttgtacgaa ataaaacgta
    17581 tcttaaaatg atttagtact aaattatttt aagatacgtt ttattttttg tattaaggta
    17641 caaaattttt agttcttttg taaactaaaa tatataaaac ttatttatac ttagttcaaa
    17701 atattgttat ttattttttc tacaactata ataaaatata aaattgatat ccaatcaaaa
    17761 aaataactat gaaatttaat agcttagata tgaatttttc tgtttttgag ttagttttta
    17821 taggtagtaa agaaatgttt atagtaatgg gataaaacaa ttcaatacct tctttagtaa
    17881 taaggtcaag acacaagtga gatagatatc ctattataaa cccactggac aaacatgaga
    17941 aaactatatt attgttagtg aagattgtca gagatttaaa aaaactataa ataagtaata
    18001 aggcaattag actgtgagta aaccctctat gtctaaacct acttccaaat aatttgtata
    18061 ttaacataaa ttttttactt atgtaagaac ctctcatatc tatatctgga aataaagaac
    18121 ctaaatatgc aaaataaata taaattataa ttaatactat tttatatgca atatcgtatt
    18181 taactaggta cagattgttt ataaagggga gtatcaaaag tgcgaatata taacctcccc
    18241 tttcatgtgt ttcttttatc atataaaaat cctcctgaat cgtcactata aacattatat
    18301 tggtaaattt agactatctt ttattatatt atatagcaaa cataagtttt tttcaaaagg
    18361 attttaatat ttaattaatc ttgagatttt aaatttttgt aattttctaa agcaccattc
    18421 caatttacta cattaaacca gttgtcaatg tattcatttc ttctattttg atattttaaa
    18481 tagtaagcat gctcccaaac atcaagtcct attataggag ttaggttttt acttacaggg
    18541 ctatcctgat ttggagtagt cataatagat aatttcccat ctttagtagc tacaagccaa
    18601 gcccaaccag aaccaaagac atctaaagca gatttttgga actcttgctt aaatttttca
    18661 aaagaaccaa agtctctatc aatagcttct tttaaagatt cagaaggtat ggttttttct
    18721 ggcgtcatta tatcaaaaaa gaatttatga ttataagctc cacctgcatt atttcttaca
    18781 gttgtagcaa tatctttagg taaagaatct aaattttgca ataattcaca taaagaataa
    18841 ttataaagct caggatattt ttcaagagca gcatttaatt tatcaacata agcttgataa
    18901 tgcttatcat gatgcagttt cattgtttct ttatctatat aaggttcaag tgcatcatat
    18961 gcataaggta atggtttaac cttaaatttg ttattttcag gtgtaaaagc aaatgaagtt
    19021 atgcactgtg agattataaa taaagacata ataactggta ttaatatttt tttcttcata
    19081 aaaatcacct cctaatatag tatttctaga aataaaaaaa atatgaaata ttaacagata
    19141 atttataaga atttaatagc aatttcattt taaattgaat aagttttaaa gccaaagaca
    19201 aaactatgaa atatagaata agactaaagg acagaaagga attttgatta tatggacggc
    19261 aatatttcaa tttattataa aggtgatata tctaaaaaag aagatattaa atttaaaata
    19321 aaagaatctg taaataatac aagactttct agtagaatag agtataagga tgaggaaaaa
    19381 acttttgatt ttgaaagatt taatgtaatt gatgctattt atggaaataa accatttgaa
    19441 aaagatggaa aagttattgt ttttaatgga aatatatata actatcatga aataaaagaa
    19501 gaattaatta aaaaaggaca caattttact acaaatgatg atattgaagt cttattggca
    19561 tcttatatag aatttggtaa gaattgtgta cataagatta aaggaatgtt caactttata
    19621 atctatgata gagaaaatga aagtatattt ggagcaagag atttatttgg gataaaacca
    19681 ctctattata taaataagga aaatgcaata attttttcct cagagtataa gtttttactt
    19741 gaatatatga aaaatttaaa tataaatgaa agaagcttac aaagttattt ttcatttcaa
    19801 tatgtacttc ctgaagatac tatgatacaa ggaataaggc tgataccagc aggtcactat
    19861 tttagggtag aaaatggtat actatcttta aagagatata ataaacttga gtttagaagt
    19921 agtacaaaat ttttttatac taaaaatcac ttaggcaata gagatgtgaa cgaggatgat
    19981 ataagaaata tagtagtaga ttcaatagta actcatatgg aagaggagaa agaaattgga
    20041 acatttctgt ctggtggaat agattcatct attataacta ctgtggcttc acaaattaat
    20101 ccaaatataa aatctttttc tgcaggcttt agtgtcaaag gatatagtga attagaagta
    20161 gcaaagaaaa cagctgataa gttaggtata gaaaatatcc agattaatat aacacaagat
    20221 gaatatataa aatcattacc gaatgtaatt tattctttgg atgaccctat agcagaccct
    20281 tcagaagtag gtctttattt cttaattaaa gaggcaggta aacatgttaa agtagcattg
    20341 tctggagaag gagcagatga attatttgga ggatataata tatataaaga gtatagtact
    20401 atgaaatcag ttgtcaattc acctacttat attaaaagta tattaggaag agtttcagaa
    20461 cttatgccaa acataaaagg aagaaattat ctttatagag ctacaacacc attagaaaaa
    20521 agatatatag gaaatgcaaa agtttttgaa aacagcgaag taaaaagatt cttttttaag
    20581 tataaggaaa agaatatata tgaatacctg ttgtctaatt tgtatagaga tgcacaaaaa
    20641 aataattacg attatataag taaaatgcaa catatagatg tgaatacatg gcttcaaggc
    20701 gatatacttc aaaaaattag caaactttct acagctgagc aggttgaact tagagtacca
    20761 tttttatata aagatgtatt tgatgtagca aaaaatttaa gaatggagca aaaaataaat
    20821 aagaataata caaaagtttt acttagagag gcgtttagag aaatagtccc agaacatgtt
    20881 gttcaaagga aaaaattagg atttccaact ccaataagag tttggttaaa agattctcta
    20941 ggggatattg taaaggaaac tatttataat tcaaatgtag atgaatttat agataaaaaa
    21001 tatgcaataa aacttttaga tacgcatctt aaaggtcata gagataattc gagaaaaata
    21061 tggactatat ttacattttg tctatggcat caattattta ttgagcataa aaatgtcgag
    21121 tattaatact tttttcaata ttaatcagag ggcaaaagca tgcaatgttt tcaccctcct
    21181 gattattatg gaataggata agtagaattt tgattgatta gtttactatc tcaataaaat
    21241 tattggcaaa tattttgaca agattacttt caacagctaa atttaagttt tgtccatcat
    21301 catatccagc ggaaatcaat cctagtaagt ttccaaacat atctaaaaga gctcctcctg
    21361 aactaccact agagattgga gctgtaaatt gtatcatttg aaccgtttca aaatcacgaa
    21421 aagctgaaat aattccatct gaaactgtat taaaaagacc tagagggctt ccaattgcaa
    21481 ctattttttg acctctcaca ggttttttac tgactttaac aggtattggc ttgcattttc
    21541 tatcaacctt tatcacagct aaatcataat ctgaatggta ttttataatt tggtaagatg
    21601 tataaacttt atcatcattt tcaaatctaa ctaaaaatga atacccatca ttgactacat
    21661 gaagattcgt aagtatataa ccttcattat ttattactac tccagaaccg ctcttaaacg
    21721 gtttattttc gttattgcac acaacaatca taacaacaga agctgataac tttgcaaggt
    21781 cttcataaga aagttctact tcctcatctt gtacaatttt tttagatgtt agatttgtgt
    21841 tattaagtgt atttttagag ttaggtttat tcgtagtagg agaagtctta ttggtatttt
    21901 cactgtaatt tatatttgta atatgccttt caaaaggtat ttctaatata tttggagtct
    21961 tcctagaaag ttcaaataga gtagaaaatt ttgaacattc aggatataaa tcaagaatat
    22021 ctttatttgg atttatatat aaaatatcac acccaagttg tgataaaaaa tataagaaaa
    22081 aaagttcttg ccttttaata tttccaaagt atactatctt tggtgaaata gtagtcttca
    22141 ccttgttata aaataattta ggtagaaaat agtctatcca acacaaaagt ttaactgcaa
    22201 agtttttgat gatagaggat gtacaatttg gcatacttgt ggaaaataaa tctaaagtat
    22261 ttttaaatgc aatcttttta gtccaattta aggtgtcatt ttctatttta catggaaagt
    22321 cgatattata taaatcccaa ctgttaaact tagaactatt ataaatatta aaaattttaa
    22381 gcatcttatc tgtttgttct ttgtcaaaat ttatttttag attgtttaat ctaatatagg
    22441 gaattgtagg attattaaaa aaataagtat ctatattttt aattttttct atgtatttat
    22501 caattgaatc atcaacacct atatatcttg taaagtagac ttctttaata tatgaagaac
    22561 gcttattttt ataggtagta tcagatataa attcaattag aggttcagta gactttttta
    22621 ttgaaatctt taatggttta atagtacaaa tcatattttt tctcctataa taagatgata
    22681 taatctatta taaaacaact taaaacaata tagtacaata attttgtagt ttcaaaataa
    22741 aatatgtact tgtttatata aatgatatat aattacatat taaacatagc ttttatgcat
    22801 ttaataaagt atgtaaaatc tatgtaaaaa gtaagaaata taaacatttt tttaattata
    22861 ttttaaaaat atcaagcaag ttttattcac aaatgaataa aaaatgttat aatatgatta
    22921 aagaaaaaga taaataatta gcaagatttg tttagctaaa attaacaagg gagcgataaa
    22981 ttatgggtat aacattatca aaaggccaaa aggttgattt aactaaagga aatccaggtc
    23041 ttaaaaatat tttagtaggt ttaggatggg atactaacaa gtatgatggt ggatttgact
    23101 ttgatttaga tacagcagca tttttaacag gagcaagtgg aagtgttact aatgatggag
    23161 attttgtatt ttacaacaat ttaaaacata catctggagc agttgagcat ctaggagata
    23221 acagaactgg cgaaggtgat ggagatgatg aacaaatagt tgttgattta tctaagattc
    23281 ctggagaaat aagcaagatt tcttttactg ttacaattca tgatgcaaca gaaagaagac
    23341 aaaattttgg acaagtaagt aattcttata taagaatagt agataaagac acaaatgaag
    23401 agttaataaa gtatgaatta ggagaagatt ttagtataga aacagctata gtagtagctg
    23461 aaatatataa gcacaatgga gaatggaagt ttaatgcact aggttctggc tttgaaggtg
    23521 gtcttgctgc attatgtgga aactttggaa taaacttata atttcaacta taacaataaa
    23581 ctaaaggggg atattttcca tggctatagt attaaaaaaa ggacaaaaaa tcgatttaac
    23641 taagggaaat ccaggtctta aaaatataaa acttggacta ggatgggata caaattcatt
    23701 tgatagtggc tatgattatg atttagatgt aagtgttttc atggttggag aatctcaaag
    23761 agttgaaaaa gatgaagatt ttatattcta caataactta aaacatccat ctggagcagt
    23821 tgaacactta ggtgataata gaactggtga aggtgatgga gatgatgagg aaatattagt
    23881 gaatttagag acaatgccaa agcatataca aaagatagct gtaacagtta caatatatga
    23941 ggctgctgaa agaagacaaa attttggaca agtaagcaac tcatatataa gagtattaaa
    24001 ttctgaaaat gatgaagaaa tattaagata tgacttaggt gaagaattta gtatagaaac
    24061 tgcaattaca gtatgtgaga tatataagta taatggagaa tggaagttta gtgcagttgg
    24121 agcaggattt gaaggtggct tagaagcact ttgtagaaac tatggcttaa atgtttaatt
    24181 taagcaatat aatatattaa atataaataa cctatacaaa taatgtatag gttatattat
    24241 ataaaatttt gtggaggttt agtatgtcga ttaatttatc aaaaggtgat aaaatagatt
    24301 taaaaaaatc taacccagga ctgagtaaca tacttgtagg tctaggatgg gaccctgtgc
    24361 aacaatctgg cggaggtttt tttaaatcgt tatttggtgg aggacaagct gatatagatt
    24421 gtgatgcatc tgtatttatg cttaatcaag aaggtaaatt aagtggaata aaagatttaa
    24481 tttattttgg aaatctaaaa agtgcctgta aatcagtttt gcatacagga gacaatctaa
    24541 ctggtgaggg tacaggtgat gatgaacaaa tcctagttaa tttggataaa gttccatcaa
    24601 atattcataa attattgttt gtagtaaata tatacaattg tgtagataga aaacaacact
    24661 ttggaatgat agaaaatgcc tatataagag ttgaagacca aggtaataag aaagagatag
    24721 caaaatacaa tctatctgat aattattctg aaaaaactac tcttatagta ggagctatat
    24781 atagaaaaga tggaagttgg caatttaaag caattggtga aggaacaaaa gatgcgggtc
    24841 ttaaagaagt aatgcaaaat ttagacagga ttgagtgtgc atatggaatt taataatgat
    24901 atcaaatatt ataatgtaga taaagaagaa gttacaaaag acttatctgt taatcctgaa
    24961 aaaggtttat cagaatcaga agtcaagact agaagagaaa aatatggttt gaatgaattt
    25021 actccaaaag aagagggtag tttttgggat gatttaaagg aaagtttaag tgaaccaatg
    25081 atagttatct tgattattgc agcagtagta agtgcagtaa ttggggaaac tcatgatgca
    25141 atagggattg taggtgctat agcaataggt atagcaatag gtatgattac agaaggtcgt
    25201 tctaagaaag cagcagaggc tctttctaag ttgactgaaa acatagaagt aaaagtattg
    25261 agagatgggg aagtacatca aatttctaag agtgaattgg taccaggtga tatagtatat
    25321 attgaaactg gtgacatggt acctgctgat ggtagactta tagaaagtat aaaccttaaa
    25381 attagagaag atatgttaac aggagaatct gatgacgtat ctaaaaagtg tgatgtagta
    25441 gtttctatgg aagagataga atctaaagga gcagtagtag tacaggaacc aatacctgca
    25501 aaacagataa atatggtgtt tggtggtaca cttgtagctt atggtagagg agctctagtt
    25561 gtaacttcaa ttggagataa tagtgaaatg ggtaaaattg ctcaaaactt atcagaaaca
    25621 gatgagcaaa ctccacttca gataaaactt ggaaatttag gtggtttgat agccaaagtt
    25681 tctagtgcag tagcaggatt actatttata tttatggttt tccaaatgat aagtaagaat
    25741 gtattaaatg tagatatgtc tggaatatta ccgtttttag aatcaataga cccagttaaa
    25801 acagcattta cagtatgtgt tgcgttgata gttgcagcag tgccagaagg tcttccaact
    25861 atgataaata tgacacttgc aataacaatg caaaaaatgg ctaaaataaa tgcattggtt
    25921 accaaaaaag aagcttgtga aacgataggt tctgtttctg taatatgttc agataaaact
    25981 ggtacattaa ctgaaaatag aatgactgta gaagttgcat atgttgatgg cagatatatt
    26041 gaaagttcag aagaggaaat aaatagttat tttgaagaaa actgtatgat aaactctaca
    26101 gctgatgtag agcacaatga tggtgatatt aagtatttag gaagtgctac tgaatgtgca
    26161 ttgcttttat attacaaaaa cgtagattat agacaagtta gaaaaaattc taatatagta
    26221 gctcaaaatc cttttacttc agattcaaag agaatgactt ctgttatagg tcaagataat
    26281 catcatgtac tattatcaaa aggagcacca gaagtcttac ttgaattatg ttcacatatt
    26341 caaagaggaa aagacatagt tccattaact gaaaatataa aacatgagat tttagaagaa
    26401 ataaagaaat tgcaaataaa atcaatgaga actttagggt ttgcatataa agaaatctca
    26461 caagctgaag aagaagcagc agtaactgct gaaagtgatg ctatgaatgt aagtgcaatg
    26521 gaaaacaatt tagtatttag tggttttgtt ggtataagag acccacttag aaaagatgtt
    26581 atagagtctg taaatacagc aaataaagct ggtgtttctg taaaaatgct tacaggagat
    26641 aatataaata cggcaagagc tataggtgaa gagttaggcc tattaaaaaa taatatgaga
    26701 gtggttgaag cttcatatat agatacttta gatgatgaag aattaaaaca agagatacaa
    26761 agtatttcaa tcgtggcaag aagtaaacca gatagtaaaa tgagaatagt ttcagctctg
    26821 caaaagagcg gagatgttgt tgcagtaaca ggtgatggta taaatgatgc tccagcactt
    26881 tcaaaagcag atgttggtat agcaatgggt atatctggta cagaggtatc taaaaacgca
    26941 gcagacataa ttttaactga tgatagtttt agtaccattg taaaaggtat taaatggggt
    27001 agaggaattt atgataactt ccaaagattc gttcaattcc aattaactgt aaatgtaatt
    27061 gcatttttag tggctataat atctcaagtt atgggacaag agatgccatt tactacaata
    27121 caattattat gggtaaacat cattatggat ggaccaccag cactagcatt aggtttagag
    27181 ccagttaggg accatgtgtt aaacagaaaa cctgttgata gaaaagccaa tataatttct
    27241 aagtcaatgg tgtatacaat agtattaaat gcattttata taacagcaat actaatgtta
    27301 caatctacat ttaatttctt aggagttgat gaagcgcata agggaacagt aatgtttgcg
    27361 ttatttgctt ttagtgcact gtttaatgca tttaactgta gagagtttaa tgcagatagt
    27421 atcttcccta attttacaca taacaaatta gcactacaaa taatagtgtt gacaggaatt
    27481 gcacaagtaa tatttactca gctattccaa gatttcttta actctgtagc aatggatttt
    27541 atgacatggg taaaagtttt atgtgtagca gcaagtgtaa ttgtggttaa tgaagttgta
    27601 aaatgtataa taagactggt aaaaccaaaa aagactgctt aaaacaaatt ttttagaaga
    27661 aaacagactg actcaaaata tgaattttgg gtcagttctg aataaacatt taaattggga
    27721 ggatagttat gggtgactca aaggtatttg aaaaaatatt ctccagccaa tcagatagag
    27781 gaaattacac tccttcaaag ggatatctaa gttattttat ttcgtatatt ggtttagaag
    27841 atgaagtttt gtacaatctc gagatattta aaacaaaaca aaatattgat agcaaaaaag
    27901 atattgcttt atttactgat gttatagcaa atcctagtga ttttgatatt ataaattatt
    27961 ttaaaagtgg acttcaaaaa tatagaacta gcatggaaga tgtagatata aatattttgg
    28021 gatttgaaga gattgattat aaaataaagc aagcaatgga tagagtgtta aaagaagagg
    28081 aaaaagaatt tactaatgat agagttaaac aaaattttat agtgaaaata atggcatgga
    28141 taaaaattta tatcggtgct ttagatataa ataaaaatga agctccaaaa gtaatatttt
    28201 atggagatat aaaaaaacat gaagtttatt tactcttaat attatacttg gcaggttttg
    28261 atgttttata tcttaatcca aattcaaaga gtaatataga tattttaaaa tcagaaagat
    28321 acaatataga gtttgaagaa gccaacataa tagaagaaaa aatttctttt gaagaaaggg
    28381 ttattttagg ggaaaaaata gataaaagtt ctgtaaaaaa agcttttact gttggggcag
    28441 aagcatcaaa gcgtataagt gaggaattgt taaatgatgc aggatttata aaaccttggc
    28501 aactccaaga tagaaaaata aaaaatctac ttctaagttc aactgttgat gaaatatcaa
    28561 tatactggaa tcaaccactt aaattaagac caggatttaa gtttaatgat gctattgtag
    28621 aagctccaaa ttttctttct aagattaatg gaatatataa cgataagaat gaatatatta
    28681 agtttttaga tttattaaga gattcggaaa gttcaacatt tattgaattt aatggagatg
    28741 tagatagatt ttcaaaagct tttacaagag aagcttttag tttatccttt ttattggatt
    28801 caaaaggtgc aatagataaa aactctgttt taaataataa agattattcc atatcaacat
    28861 tagcattgaa tcaacaaatt atgattttag agaaagtgga agagttgtta gaaggaagta
    28921 tgtttttgaa tggtttaagt ggagaagaca agataaaagg tctatttaca gtacttcaca
    28981 tggataagaa atttgttcat atgatgaaca atttcgatta ctcacttata aacccaaaat
    29041 tgattatata catgtacaag agtattgtat ttgataaaga aatagttttt cttatgcttt
    29101 tacttagtaa gattggattt gatattatca tattatgtcc aggaggagaa aacaatatag
    29161 agaatgttat aaataaccaa ttgattgatg tacacagatt ggataaaatg gtatatgacc
    29221 ttaaattaaa ttcgcttgaa aatgatatac ctttacttaa aaaaattttt ggaaagagga
    29281 gacgatttta gatggggata aatataaata gtttttcaaa agataagaac tctgtagagg
    29341 ttactgagaa tttgcctaca gcagttcaag aagaaaactt cgatataatg gaatatacaa
    29401 ataataaaaa aaatgaactg agaaagtcta aggaagttga ggcattgaca tctcttatag
    29461 aagtagaaaa tccagatacg attttacagt ttggtaggaa agcatctgaa ggagtagcaa
    29521 gagtttctga tagcctttta aatacaataa aattaaatag aaatgaagaa aattctaaaa
    29581 tgctggttca tttaactaaa ataatggaca agtttgattt agacgatttt caagaaacta
    29641 aggaaccaaa tttcgttcaa aaacttttca aaaaagctaa taatgccatt gaaatgatgt
    29701 ttcaaaagta tgaaacattg ggaggagaag ttgagaaaat tcaaattgag cttgaacaat
    29761 acgaaagaga tatagcactt tctaataagc aaataggtgc tatgttaaat gaaaactttg
    29821 agttttacaa tgaacttcaa aaatatattg ttgctggaga aatggcaata gaagaaatgg
    29881 ataatgaaat actacctttc tttaaacaaa aatcagagac tagtggagac caaatggatg
    29941 ttgtcaatta tcaagaacta ttaaaagttt atgatatgtt aaatcaaaga gtctatgatt
    30001 taaggatagc agaaaatata gctatccaaa caatacctat gcttagaggt atgcaacata
    30061 ataattatgg tttaattaga aaaataaata gtgcatttgt cgtaacttta ccagtattta
    30121 aacaatgttt atctcaagct atattactta aaaagcaaga attacaagca aaatctctaa
    30181 aagcacttga tgacaaaact aatgaattat tgcttagaaa tgcacaaaat gtaagtactc
    30241 aaagtgcaca aatagctaga atggctggaa caagttctgt tcaaatagaa acattggaaa
    30301 aaatgtacaa tactattaaa tctggtatag atgaaactat gagaatagaa gaaaacaata
    30361 gagctttaat taaggataat acaaagagat tggaagaatt aaatacgact ataatttata
    30421 ataagtagta ttatattaag ggctaatttg tataaagttg gccctttcta tgtatatgag
    30481 gaggctagac attgaaatat ttcgattata tctgcaaaga tgatttggag agaatttttt
    30541 tgaaggagcc agaagatttt agtgctaaga ctgaaaaaga tgtgttgaaa tatgcactgg
    30601 gcgctttttt atacgttcca gctactcaat ataatatgat ttataagagt attatagggg
    30661 atgttaaggg agttagacca ttagctattt gtttagaaga tgctgttgga gtaaatggag
    30721 agttagaggc tatagaaaat cttagattaa ttttaaaaaa tattagcaat gaaagtataa
    30781 ctaataaaga tggaatacca ctaatttttg taagaataaa agatgtggag caactgttga
    30841 gaattaaaga gattataatt aaaaatagac attctataac aggaatatta attcctaaag
    30901 caaattcgga gttaatagaa aattgtatag aagctttaga ttctatgaat cttcaagata
    30961 tgtatgttat tccgataata gagacaaaag aatttatata taatgaaaaa aaagaactta
    31021 gttttactaa tttgtacaat gctattttaa gacataagtc aagaatatta agcattagag
    31081 taggcataac tgatatatta gggatgtatg gtataaggag agataagaac ttctctatat
    31141 ataataattt gatttgttct tcatttatat tagatataat cacatatctt caaagaccag
    31201 agttagatat acctataagt ggtggagtat cagaattttt tgatatgacg aataaggata
    31261 taagaaataa gtatatagaa gaaatattat tggataaata tcatggatta attggaaaga
    31321 ccgtaattca tccaatgcaa attcaaattg tacaagcgct atctacagta tcatatgaag
    31381 attttactga tgctttggat atactggata gtacagacag taagtatggt gtgagcaagg
    31441 gtgtattagg agagagaatg aatgaaacaa atccacattt tttatgggct aaaaaaacat
    31501 tgattctatc taaaatatat ggtgtattaa ataaaggagt agactatgaa gaattgctta
    31561 aattttaatt gtgagattga cattattgat aatccattga atttagaact aaatgatttt
    31621 ttagacgtag gaataagaaa taatagcaaa agacgttttt tgtttatctc aaagaaactc
    31681 ggtaaacatt tagcatgtaa gccaagtgag atggataatt tgggaaaatt aatggctaca
    31741 atttataatg aaaaaaataa ggaagaatca aatggtactg ttatagcttt tgctgaaact
    31801 ggtacagctg ttgggcatag tttttttgat tacttatgtg gagattatga atttattcat
    31861 actactagag agcagtttga cgagttagaa aatctggaat ttttagagga acattcccat
    31921 gcaacagacc agaatttata ctttggtatg cttaacaact ttaaatttgg agatgagata
    31981 atattggttg atgatgagat taccacagcc aatacatgca tgaatataat taggaaaatt
    32041 caaagcattt atcctaaaaa gaaatacact atatgctcaa tactcaattg ggtaagtgat
    32101 gaaaatttaa gtaaagttac tcgtttagaa agagagctag attgtaagat agattttgta
    32161 tacttattta aaggaaactt taaattttat atagatgaag atattatttc aaattacaac
    32221 gataattata gtattactaa attagagact atttcaagtg ataaagtaaa tttagtagta
    32281 aatcatattt atgttgattt agaagattat attggaaata agaaatatgt aaaatataca
    32341 ggaagatttg gaattaatag aagagaacaa tttagattaa aagaaatcgt taagagagaa
    32401 agtaaaaaaa taactatggc cagtaaagaa tctttaaaaa atgaaaaaga aaagattcta
    32461 tttttaggta ctgaagaatt tatgtatata cctatgctgt ttgcaaaaga aaaagaaaat
    32521 caatatgata tatactatca ttcaacaaca agaagtccaa ttattaatat tgataagaat
    32581 aattatccta ttaaaagtaa atttatgcta aagagttttt ataatataga tattcaaaat
    32641 tatatttaca atatagataa acataatttt tctaagtgtt atttatttgt agagctgaat
    32701 aaaagtgaaa attcttatct agaatttatt gatataatta aaaaaacaag tataaaagaa
    32761 ttaactatag tatgttgtag ctaaagtgtt ttaacaggat aaaatatatc acgattttaa
    32821 gataggagtt gagtcatatg agagatttta gcacgtattc taaagatgat gttatttttt
    32881 tattaaaaga tatatcaaat ttaattgaag aagaaggaaa taaagaaaga gaattaaaaa
    32941 tacaaaatgg tagacattat tcagaaatga taccaataga gtatgaagtt agtgaagatt
    33001 atctgaattt atatcatgag aaactaagag aaaataaaga taaacttgca ttttctatag
    33061 gagttatgtg tgaaaaaata attaaaaaaa atggaaatga tgtagtacta gtttcacttg
    33121 ctagagcagg aacacctatt ggtattttgg caaaaagata tataagaagc aagtataatg
    33181 taagtttacc tcactataca atctctataa taagagataa gggaatagat atgaatgcaa
    33241 ttgaatatat agtaaagaat catccgagct caaaaattca atttttagat ggatggactg
    33301 gtaaaggaac tatatcaaaa gaacttgaaa aagcatgtga tgaacttaat gttaaattta
    33361 aaaaatattt tgactcaaca cttgctgtat tagctgaccc tgctggatat tcaggacttt
    33421 atggaattag agaagatttc ttaataccaa gtgcatgttt aaattcaaca gtttctggtt
    33481 tagtaagtag aactgtacta agagaggatt taattagtaa aaatgacttt catggagcta
    33541 agttttatag acatttaaaa gataaagatg aatctatgaa ctatatcgaa actatagaag
    33601 aatgttttaa aaatcaattt aagaatatat ctgatgaagt tgaaaactgg gaaagtgaca
    33661 ttataacaag agatggatac tttgatgttt taaatataaa agaaaagtat aacataacag
    33721 atattaactt tatcaaacca ggtgtagggg aaacgactag ggttttactt agaagagttc
    33781 cgtataagat tcttgttaaa gacttaaatg ataaatcttt agaccatata ttcatattag
    33841 ctaaggagaa aaatgttgaa gttgaacaaa tggatttaaa agcctataaa tgttgtggaa
    33901 taataaaaaa tatgaaagat atttaggaaa tatattagac aggagaatat tgaatgattg
    33961 ttttttcaga tttagacagg agtatcattt actccaataa atttttaaat gctgatagta
    34021 aatatgctaa tatagaaatt tatagggaaa aagaaatatc ttatatatct ttagatacta
    34081 taaatttaat aaagcaaata caatattatg gtatgtttat acctacaact actagaacag
    34141 tggagcaatt taagcgtata gaatttaata aatatgggat ttattttcct tggagtataa
    34201 cttcaaatgg aggagttata cttaaagata atgaaatatt gaaatcatgg agtgaaaaaa
    34261 tagataaact aaaatctgat tatgagccca ttgaaagtat gattcataaa tttaaagact
    34321 atttgaatgt agatggaata actaatttta aagttgcaga agatacattt ttttatatag
    34381 ttgttgattt atcaagattt aatttggatt caatcaaaga atatacaaat atattggaat
    34441 caaaaaattg gaagttttat gtgagtggca gaaaaatata ttttatacca aaagaaattt
    34501 caaaagaaaa tgctataaaa tacttgacta aagaattagg aatagaatat ttttatgcag
    34561 ttggagattc tattatggac tatggtatgc ttaatatctc aaataaatcc tatgtattga
    34621 agcatggtga tataaataaa aatgaaatag aaaattcatt tatatcaagt tctttcaatg
    34681 gaatgagtgg aactgaagag atactatcta acattttaga cgagaactgc ctacttaata
    34741 tataatgact gatatataaa taataaacta gaaaaatctg aaataaatta tagtaaagtt
    34801 tatcatacta atttatttca gatttttatc aatttatatt taagtaagaa ctcaatatgt
    34861 taaaatgaag gtggagtcat tgcccagact gagatacata cctcatcatc ataattttca
    34921 tacacatgtg gtatagtact gttaaaataa aaactatctc cttcctccaa tagatattcc
    34981 ttatttccaa gtgttatctt cattttacct tttattatat agccacattc ttctccttcg
    35041 tgtgtcacaa attcactgtt tttgtgtgta tgaccatcta gtgtaacaag tataaattct
    35101 atttttttcc cagataaatt aggaacaaga agttcgtaaa attttgtaga atcattagtt
    35161 actatttttt ttcgattatt tttctttact actatatcag agtcttctct tccaatctct
    35221 tcaaaaaaat aacctatatt tatatcaaga gcttttgata ttttccacat tgctacaata
    35281 gatggaacaa ccatattacg ctcaatttga cttattaagc ctgtacttaa atctgaattt
    35341 tttgctaaag tagagatact tatattttta gattttctaa gagatctaat tttgcttcca
    35401 acatctatat tcattagata caaaccccct cagacatgat tataacatat aatttataaa
    35461 gattaataaa ataaaaaaaa agttttacaa tacaagtatt ttttatgcta tattgaattt
    35521 tctgaaaaga tgcattataa tagtattaat attcaatata ttgaatattg ataacgatat
    35581 tttaatttaa tgaaatggag gtaattaaga tgaagagttt tgtaagtcct gataatattt
    35641 gggtattatg ggcagttgta actggatggg cagcatttag tatttatttg gaacaaaagt
    35701 acaattgggc atcaaaagtg tcgggagcaa taatagctct tgtaggagca atgttattat
    35761 caaatctaaa tattatacca gtagagtctg ttgtatatga ccaagtatgg ggatatgttg
    35821 ttcctttagc catagcttta ttgttatatc aatgtaacat taaaaagata tggaaagaaa
    35881 gtggaagatt gctcattata tttcttgtag gttctgtagg aactgtactt ggagctatga
    35941 ttggattttt agcattaaaa aatgtagtac cagatttaaa tattgttgca gctatgatga
    36001 caggttctta tataggtgga aatgtaaact ttgctgctat gtcaggggcg tttgatgcgc
    36061 caggagaatt agtatcagca acagttgtag cagataatct tttaatggca ttatatttct
    36121 ttgtcttaat agctatacca tcaattggat tttttagaaa acattttaaa catccacatg
    36181 tagatgaaat ggaaagtata ggtataactg aaggagaaac agtagcagca aattattggg
    36241 gaagaaaaga aatatcttta aaagatatag caatagccat tggtagcgct tttataattg
    36301 tcgcagtatc tgtagaacta tcaacttggt ttaaagctat aataccatta tcaaatcctt
    36361 ttttagcaat gttaaatact ttatttggaa atcaatatct aataataact actttgacta
    36421 tgttgtttgc cacatttatg cctaatttct ttggtgatat aaaaggagca caggaattgg
    36481 gtacattttt aatatatata ttctttgttg tagtaggtgt tcctgcttca ataacattaa
    36541 taattcaaaa atcaccatta ctacttttat actgcggaat aatggtacta ataaacatgc
    36601 tagttacatt tatagttgca aaaatattta agtttagttt agaagaagct attcttgcat
    36661 ctaatgcaaa tattggtggt cctacaacag cagcagctat ggcaatatca aaaggatggt
    36721 ctaagctagt agggccaata cttatagttg gaacatttgg atacatagtc ggtaattatt
    36781 ttggtctttt agtaggaaat attttgatat aattttacgt gaaaaaaagt tgttttttag
    36841 aaagattttt atttaattgg aggttgttat gattttcgat ggacattcag atacttgggc
    36901 agatgtaaca ataagaaggc ttaacgggga aaaagatgta tttagaagaa tccatcttga
    36961 taattttaaa agagcaaata tagaaggagc tatttttgta atatggatag acccaccata
    37021 tgataaagag cctgaaaaaa gagttaaaca aattataagc tctataaaag atgaaattga
    37081 agatatgaaa gatgttgtaa acatagtaaa aaaatattca gatatagata aaggtataag
    37141 tgaaaacaaa ataaatattt taattggtct tgaaggatta agccatattg gaagaaatat
    37201 agatttacta gattattttt ataaagaagt tggtgcaaga catgcatcat taacttggaa
    37261 tgaacagaat gaacttgcta caggatgttt aggggatgaa aatcgtggtt taactgaaat
    37321 aggtaaaaaa gcagtcaata aaatggaaaa attgggcatg atagtagatg tgtcacattt
    37381 aaatgaaaaa tcattttggg atttaatgtc tgttgcaagt aagccagtta tagcttctca
    37441 ttctaatgct aggagtttat gtgatgctaa aagaaatctt acagataatc aattaaaaga
    37501 aatttcaaat acaggtggat tagttggaat aaatagtttt agaggattta ctaatagtaa
    37561 tcctaagaag caagatttaa tacatttggt tgaccatata gactatatgg taaatcttat
    37621 aggtatagaa catgtatctt ttggttttga ttttagtgat tacttaggga aagagactat
    37681 aggttctttt actggaaatg ctagtgtgcc aagtgtagat ggtcttgaaa gcacacatac
    37741 agcacagaac atagtagtag agcttgaaaa tagaggttat aaaaagaaag atatagagtt
    37801 aatctctagt ggtaattttt ataggctctt taaagatata ctaaaataat ataataaaga
    37861 acttaaattt ataaaatagt atatttatac aaataatatc tacatattta aattggcgtt
    37921 cataatttat taaattaaat tttaatgtta ctagaagttt caattctagt aacatttttt
    37981 atgttaaaaa cagatataga tatatattga caatgataat tattattgat aaactataaa
    38041 agtgaaaatg ataataattt tcattttaat taataaaaga tttttaagga gggagaatga
    38101 agaaaaggta tttagtcata ggaataataa ttttgtctta tttttcttta tttataggag
    38161 ctgaagatat aaatataatg catatatttg ccaaaaatca gcataaactt atgatattta
    38221 tcatgagtag aataccaaga ttaataagta tattgattgc tggtgtagga atgagcatag
    38281 caggtcttat aatgcaacag ataagtaaga ataaatttgt atcacctaca acaggtgcta
    38341 caatagatgc agcacaattt gggatagtaa tatgtatgct tttagtacca actgcctcta
    38401 tttttacaaa gacaataata gcatttgtat tttctcttgt agggactttt acgtttatga
    38461 aaataatagg gaagttacaa tttaaaaata taatctttgt accattagta ggtataatgt
    38521 ttggaaatat aataggttct atgacggatt ttatcgcgta taaatacgat ttgagtcaaa
    38581 atgttagttc ttggatgcaa ggtgactttt ctatgatact taaaggaaat tatgagatat
    38641 tatatatcac aatacccctt ataatattag catatattta tgcaaataaa tttactgttg
    38701 ttggtatggg tatggatttt gcgacaaact taggtcttag ttacaaaaga attgtcaata
    38761 taggtctgat aatagtagca cttgttacag tatgtgtagt cgttacagct ggtaatatcc
    38821 cttttatagg tctaatagtt cccaatatcg tatccttgta tatgggtgat aatataagag
    38881 caagcatatg gtatactggt ttacttggag cgatatttgt acttatatgt gatatttttg
    38941 gaagaattat tatttatcca tatgaaatat ctatagggct tacagttgga gttataggaa
    39001 gtatactatt cctttattta atattaagga ggaatgtaaa tgaagcttag tctcaatcaa
    39061 aaaatttact ttgtaagtat attactattc atatcaatag cactttttat aatttatgga
    39121 atagacatga atcatttaga atatgcatta tcacaaagaa taccaaaaat atttgctatg
    39181 gtattaggtg gaggatgtat agcatttact actgtagtgt ttcaaacaat tacaaacaat
    39241 caaatattaa caccaagtgt actaggttta gattcattgt atgtaatgat tcaaactata
    39301 atagtattca tatttggttc aagcagtagt ctgattataa atgaaaatta taattttatt
    39361 attaatgtag ctatgatgat tggagcttca ttgttattat ataagacgtt atttgaaaaa
    39421 aataaaaata atattttctt tttaatccta gtaggaatga tatttggaac cttatttaaa
    39481 agtgcaacaa catttattca ggtaatgata gaccctaatg aatttttagc tttacaaact
    39541 agtataatgg caagtttaaa caatataaac actaatgtat tgttaatagc atttataata
    39601 attattgcca taataccttt tatatatgat gaaataaagt atttagatgt attgtcgtta
    39661 ggtaaagaac aagcaattaa tttaggtgta gattttgata aagcagttaa aaaaatgata
    39721 atattaatag caattttagt ctcaatatca acagcactta ttggacctat gacattttta
    39781 ggacttttac ttgctaatat aacaagagaa atttttaaaa catataagca tacatacttg
    39841 atttcgggtt ctatgttgat agggatgatt acattgataa taggtcaatt ttttatacaa
    39901 catgtattta agtttgatac aactttaagt gtagtaataa attttatagg aggaatttac
    39961 tttattcaat tactattaaa gggggcaaat agatgataga gataaaaaat atatttaaaa
    40021 gatataagaa taaaaatgtt gtagatgatg tctcttttag tatagaaaag ggaaagataa
    40081 catcttttat aggaccaaat ggagctggaa aaagtacagt actatcaata gttacaagac
    40141 ttataggagg tgatggtgga gaagtaataa tagaaggaaa aagcttgact aattatagca
    40201 ataaagaatt agcaaaaaaa atagctattc ttaaacaatc taacaatata actttaaagc
    40261 ttacaataag agaattagtt ggatttggaa gatttccata tagtgaaggt aatctaacta
    40321 aagaggatga aaattatatt gatgaagcaa tagaatatat gaagttgact gatatacaac
    40381 ataagtattt agatgaattg agtggaggtc aaagacaaag agcttatata gcaatggtaa
    40441 tagctcaaga tacagagtac atattacttg atgaaccact gaacaatttg gatatgaacc
    40501 attccgtaca gatgatgaag gtacttagaa gtctttgtga tgagttagat aagactatag
    40561 tattagtaat gcatgatata aattttgcat catgttattc agataatata gttgcattaa
    40621 aaaatggaaa agttaaaaaa gtaggtcgta cagatgagat agtaaatgaa aaagttttag
    40681 aagatattta tgagatgaat tttaacatta agaatataaa tggaaatcga atctgtattt
    40741 atttttaaaa tattgtatat gaaaataaac ttgctatatg attttttata aagtttttaa
    40801 attaaaataa agattaatag gagagaggaa aatattgata tgaataaaaa agcagcaata
    40861 gtagcagcag tagctattat aggattagtg acagtgtttg cattaggtgg aagtaaaaag
    40921 aatgaatcaa aaacatcaga aaattcaaat aatactatga agataactca taacttggga
    40981 gaaacagatg taaaattaaa tcctaaaaaa gtagtggtat ttgattattc ggctttagat
    41041 acaatggatg cattaggtgt agctgagaat ttagtaggac ttccaaaagc gagtttacca
    41101 gcatccttag aaaaatataa ggatgacaag tatgcagatt taggaggatt aaaagaacca
    41161 gatttagagg gtataaagtc ggcaaatcca gatttaatta taataaatgg aagacaagaa
    41221 gatttttatg agcaattgtc aaaaatagca ccaacaataa gtacaagtaa agatgataag
    41281 aagtacttag aatctgttaa aaataatata gacaaaatag caaaaatatt tggagtagaa
    41341 gaaaaagcaa atcaagaatt tagtaaaatt gaaaagaaaa tagaaacttt gaataaaaaa
    41401 gtaacagata aaaatttaaa tgctttaact ataatggtaa atgaaggtaa tttaagtgta
    41461 tttggtgaag aatcaagatt tagtatatta tacaatagtt ttggatttga aaataaagat
    41521 aaaaatataa aagaatcaag tcatggacaa aatattactt ttgaatatat agctaaacaa
    41581 aatccagaag ttatgttcgt tatagataga ggaatagcta ctggcagtga tgtaaaagaa
    41641 agctcaactg caaaatctgt tttgaacaat gatataataa aatctatgga tgcatataag
    41701 aatgataata taatatattt agattcacca acatggtatg taaatgatgg tggtctaaca
    41761 tctttaaata aaatgataga tgatgcttca aaagcggtaa attaataatc cgatataatc
    41821 aaaatatatt ttttataaaa tgattatcaa ataaactagg agtttttaag aactcctagt
    41881 ttattttttg cataaaaaag atatagttta aacaataata ttatctataa taag
//
LOCUS       DAMJVG010000030        40566 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.030, whole genome shotgun sequence.
ACCESSION   DAMJVG010000030 DAMJVG010000000
VERSION     DAMJVG010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 40566)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40566)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40566
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.030"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            51..227
                     /locus_tag="PC512_001708"
     CDS             51..227
                     /locus_tag="PC512_001708"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441454.1"
                     /translation="MNLKKKEKIVKPVLKKLTEIVLNILSKKILNYAIYAISVLIVTK
                     VVINIDLYISILYY"
     gene            328..1065
                     /gene="cas6"
                     /locus_tag="PC512_001709"
     CDS             328..1065
                     /gene="cas6"
                     /locus_tag="PC512_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endoribonuclease Cas6"
                     /protein_id="HDF2441455.1"
                     /translation="MSRISIFMESCNGKFPNENSMLSVSFIKNILNAENKDFAKNIFN
                     YGEERKNNKQIKDINTAIYIPNLIRSKNELLVDGDIIFNISFYNYSMFSKLYNGILKV
                     KELEYKGYRFKIKNIKIHKEHEIKENGVIFKTMSPIIVKNKEGKYLDVEDSNYIECLN
                     YIANLTLESIRGSGLRKPLEFIPLNFKKRVLKEKIRGFKEREFYYINAYAGTFFLKGN
                     MEDLNALYKMGIGYRRTENAGMVDILK"
     gene            1070..2545
                     /locus_tag="PC512_001710"
     CDS             1070..2545
                     /locus_tag="PC512_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441456.1"
                     /translation="MREIKAKFYRSGDIVRDIGIVYFCELLMDLKNELEKNDYKLKFT
                     CELNRNYLSLESAEYIDPKYISDYILENQLFKVFKNGKKETLEKIFSNIDNLTYVNFI
                     EELDKSSATEKQKEGIKKDFKNRRFPYVRNSGKYGLNTSLENMEKNVKRIVDIVIKSN
                     IEIDEIDKLDLKQYEEKDSVCNVCNINKTTKLDIDLRERKDSKYNFLFRGAEKSGFKR
                     SGQVESNICFECEFFNLMCLLYINLKRPMVFAYTNDLRELAFLNHKIMLKRKMYSDKS
                     FYKKLLHEKISSIRLYRIDIDTNKGIILKFDSIIEYKELLKKIELIDIIDNYNFSREP
                     MNTRNLGKKMINNGNLSNLKELLLDNISVLRQLTGTSREMDFVSSSYNIGLYIKLCWI
                     VDGREEYKMKNYIESNLIYSRVGKDLFNKMTDESRRKNFSMKVIQLLKSNDRTQLFQT
                     IMHVLVSNGILIGEGFVEGLMQSSELELNTNVGLFIQEIMK"
     gene            2565..3581
                     /gene="cas7i"
                     /locus_tag="PC512_001711"
     CDS             2565..3581
                     /gene="cas7i"
                     /locus_tag="PC512_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein
                     Cas7/Cst2/DevR"
                     /protein_id="HDF2441457.1"
                     /translation="MNEKRVKGVTLTILTESPVPLSYDQGYGNYTPIKKEQYRDKVHA
                     KTSIATITYDLRRILHQEYGWNLSNIVFGKKGNIYPSIKKNVGCVDENGLETDVFGYL
                     IPLKEKGSISKASPLRIIPFRSLNSYRGSTQLITNRGFLSSEFGRKYYDEREENEVLR
                     DENFPTTQALAIEETLSDYYVYTITLELDRIGVVEVEEDGKLLLPEERKFMSKELREK
                     AVKDILDAITVFTRNIKHSSVLLKPLAVMGGAFDKVVPFFWDDVDYNADSGEINLEGV
                     IETIESYSLKESNTILAINDRLKISNKKELNKFNLSKYPVKEIKNLADRLEIGEDNMW
                     YLKE"
     gene            3597..4394
                     /gene="cas5"
                     /locus_tag="PC512_001712"
     CDS             3597..4394
                     /gene="cas5"
                     /locus_tag="PC512_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas5"
                     /protein_id="HDF2441458.1"
                     /translation="MKVLQCKLKQPTAHYRDPKVFQNEYISTLNLPSKTTIMGMITYL
                     CDRRLNSDIDIGIIGTHHHRELEFSRGENIDFWNEYTNMRKGKDKEKFLLQGNYYDYY
                     KEHKAQNSILNYEVLKEVELTIFISCKDDEELEFIRKKLESPCKYANLGRKEDFVIPS
                     EKGCFVKEVELKEVIPMNTRDAIKENIKLKNTYVRVDLRDKENVETIINQGVLIALPY
                     KYKDLEANRDDRVYEFCHYIYVDNDGIYPKNIKVNVCIDTKEVFTWL"
     gene            4421..6829
                     /locus_tag="PC512_001713"
     CDS             4421..6829
                     /locus_tag="PC512_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HDF2441459.1"
                     /translation="MKNIMQKEILAKSYNLRTNQQEQTLVEHIKDLFEVLESILELNL
                     YSDKDVEILKICCALHDLGKINSIMQQKMEINNKISYSCSEEERKKLESDKKSLKKIA
                     RHNIFSGAFLKDILEKMNLSEEDKLYIYKSIMLHHGNYEDYMRLSISKVQEEIYEYIE
                     KGILEKEEFNLKDIESYINSILNVDFKFGEDVLDYDYIDKLSESMFIDSDYNNGQIDD
                     SVLNYRKFKYILYKGMLNLIDHSASSRQKGIKFYNDFTDEEIDNMILNEIYKSQGNLE
                     KNNIEFNTIQKRLRELSGRNVLTVAFTGSGKTAADYRKTFKRKFFLVPNKISAESFYR
                     KNIFQNKNDLDTRSSNDYIGLLHGDINLYSENEDNGEHDFVLTLRDIDLSINFCKPCV
                     IATVDQLLLSMFKFPGYEKIFAAVKNASITVDEVHLLEPKMFLILIYFMQFACKYLDV
                     DFHLMTATLPKSYKEQMINKGIIFQEESNENVTDKGEIVFIESNKEEEICEGKDVKVS
                     FIKEKEIKSIVEDALENKQKILIIKNTIDSVNRTYEFLKENLSDKYGGVDIDVLHSRF
                     KFKDKKEKYSKILNGEGDIWISTQSVEISLDLDFNIIISDLATMDSLIQRMGRCNRNN
                     KYEYGNFYILPSEDKIYDNKLKNTTKNILKDILKTNSIFTMGIRKTILDDYYDNSVVK
                     KYFEENFISCDKEIKNIYGINKEIFDGLDLIFNFEPYKNIVDSKKEAAKIFRDVDVSY
                     KIILEEDFYKEDRELQQDSIQVSGFIFNRLYYYGLISKVEGYMVLKSSSKFEYNSTVG
                     LILK"
     gene            7271..8218
                     /gene="prmA"
                     /locus_tag="PC512_001714"
     CDS             7271..8218
                     /gene="prmA"
                     /locus_tag="PC512_001714"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HDF2441460.1"
                     /translation="MNNWIEVTIKTTTEAVEPITNILYEQGAGGAVIEDPKDFLFQKK
                     NELDWDYVEEEVFKKNEEDDVLIKTYVSEEKNVMEFVEIIKQKVLGLKDFGIDIGEGS
                     VSLDQVNEADWANAWKAYYKPTKVGQRVVVKPTWEDYAMQEGDLIIELDPGMAFGTGT
                     HETTSMCIRELEKYVNKDSKVFDIGCGSGILAIAAAKLGAKEVVAVDLDEVAVKVAKE
                     NVLENKVEKSVSVMHGNLTDVIKDKADVIVANIIADIIKILAKDVQNFMKEDAIFISS
                     GIILDKVEEVKESLIENGFEIVEVQKLGEWSAIVSKLKK"
     gene            8237..8995
                     /locus_tag="PC512_001715"
     CDS             8237..8995
                     /locus_tag="PC512_001715"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HDF2441461.1"
                     /translation="MDRFFVEKNNINLQDKTCTIEGEDVKHISKVLRCKLGEKLEICD
                     KNNNEYICEIMNIDKSIVNLEILEKVDINRESELKVRLYQGLPKAPKMEMILQKLTEV
                     GVEEIILVQTKRSVVKVDDKKEDKKFERWERIIYEAAKQSKRGKIPKLRGVLSFKEAL
                     EDMKKNNVNICPYENERTVSIKHALKKCDSNIDSVGIFIGPEGGFSEEEIEQIQKNNC
                     NVVSLGPRILRTETASVVASTIALYELSDLGGEK"
     gene            8997..10295
                     /gene="mtaB"
                     /locus_tag="PC512_001716"
     CDS             8997..10295
                     /gene="mtaB"
                     /locus_tag="PC512_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-
                     methylthiotransferase MtaB"
                     /protein_id="HDF2441462.1"
                     /translation="MKKVAFYTLGCKVNQYETEAMLELFEKDGYEQVNSEEYADVYVI
                     NTCTVTHMSDRKSRQYIRRVKKKNPDAIIAVVGCYSQVSPEEILDIEEVNLVMGTNDR
                     RKIVEEIKKINSSKKVSTVDDIMKVKAFEEIEISQTNGKTRAFMKIQDGCDRFCTYCI
                     IPYARGRVRSRDIDSIVDEVKKLANNGYKEVVLTGIHVASYGKDLKDRDIKLLDVIKQ
                     INQIEKIERIRLSSVEPILFTDEFVNEVLKMDKVCPHYHLSLQSGCDETLKRMNRRYT
                     TLEYKTIVDRLRSKMPDVAITTDVIVGFPGETNEEFKKTYEFLKEIELSQMHIFKYSP
                     RKGTPAATMENQVDPQMKHFRSEQLLNLSKVNFNKFATKFIGRELDVLFEQNIEGNKY
                     EGLTSNYIRVVVESDKNIQGQILKVKINDVKDEYVEGILL"
     gene            10338..10688
                     /locus_tag="PC512_001717"
     CDS             10338..10688
                     /locus_tag="PC512_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine triad nucleotide-binding protein"
                     /protein_id="HDF2441463.1"
                     /translation="MDCIFCKIANGEIPSTKVYEDDRVLAFNDLNPVAPYHILVVPKK
                     HYDSLIDIPDKEMDIVSHIHVVINKIAKEKGFDQTGFRVINNCGSDGGQEVKHLHYHI
                     LAGKKLPNYEAGQN"
     gene            10851..11030
                     /locus_tag="PC512_001718"
     CDS             10851..11030
                     /locus_tag="PC512_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HDF2441464.1"
                     /translation="MSEVRVRENETLDSALRRFKRQCAMSGIMSEVRKREHYDKPSVK
                     RKKKAEAARRKNAKK"
     gene            11060..11503
                     /locus_tag="PC512_001719"
     CDS             11060..11503
                     /locus_tag="PC512_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HDF2441465.1"
                     /translation="MSLKQKLQEDLKSSMKNKDTVRKSVVTLIRASIKQYEVDNRVEL
                     DEDGIIDVIAKQLKQRRDALVEFEKAGREDLIKETEGEIEVLKEYLPQQLSEEELEEI
                     VKSTISEVGATSMKDMGKIMSVIQPKVKGRADGKLINKLVKQNLQ"
     gene            11614..12111
                     /locus_tag="PC512_001720"
     CDS             11614..12111
                     /locus_tag="PC512_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HDF2441466.1"
                     /translation="MIISVKEIRNFLINIFIPLIIGYLSSILTMIISGTDISTYYLQL
                     TKPSFAPPAFIFPIVWTILYILMGISSYLILRKGYNLPKVRDAIFYYGLQLVLNFIWS
                     ILFFGFGLRFTALIDIIIMILVSIIMISKFSKIDKRSGYINLIYLMWLVYAGFLNYFI
                     WFINK"
     gene            12304..12867
                     /gene="raiA"
                     /locus_tag="PC512_001721"
     CDS             12304..12867
                     /gene="raiA"
                     /locus_tag="PC512_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HDF2441467.1"
                     /translation="MQIIVSGRQMKLTDGIKGYVDGKLSRLEKYLDPESEVKVTVSAK
                     KDRQKVEVTIIPINGQIIRAEDVEDDLYAAIDIVCDKLSRQVVKYKTKVKDKVQNNKS
                     IRFENLDFIDNSSEFDDYDYDDEEDENIVIERRKKFNVKPMSSEEAILQMELVGHNFY
                     MFRNQDNFEINIVYKRKAGGYGLIEQD"
     gene            13080..13316
                     /locus_tag="PC512_001722"
     CDS             13080..13316
                     /locus_tag="PC512_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YabP/YqfC family sporulation protein"
                     /protein_id="HDF2441468.1"
                     /translation="MLEISTDLQVNQPVITVTSNTFISIENYLSILEYEVDLIRIKTK
                     VKTIKISGDKLSLKYITDSEIGIKGIIYNVEYVD"
     gene            13329..14672
                     /gene="yqfD"
                     /locus_tag="PC512_001723"
     CDS             13329..14672
                     /gene="yqfD"
                     /locus_tag="PC512_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YqfD"
                     /protein_id="HDF2441469.1"
                     /translation="MISFIRGYYVIVVEGVGLEQFLNHLIRNGISVYNVTRIKNTKME
                     FHIDRQDIKEFKNVYRGSKFDIKVKQKTGVPFIIKRVYKHKGMWICALVSLFLLMSTS
                     QFVTDVYIQSPEGIKKEALRNELYKVGVRPGVYKKSIDRKEVRDHMMSKFNDVAYLSI
                     NVKGTNIFVTVTKKAESLKSTDQSNYCNVIALKNGIIEKVIPRSGKSVIKSGDIVQKG
                     DVLLNGANTKSIPEVWASTFYESTKKASYVDTVNKKTGEKKNIYTLSFYDKEFTMRKN
                     IKYKDYVVENKEKKLSIGNYTFPIKIKTSTFYETKKVEVKRNKEELKKELSEKALKEL
                     EYIIPASARIIDVKHNFKVNKNMLEYLITVQTSENIAKIYPLSKSEAERFIKEESKPD
                     EGEEEVPSNPEKRPLNDIRNEFDEDNKDNKDQNNSDENNSNQNSNNSQNNNSNNN"
     gene            14611..15726
                     /locus_tag="PC512_001724"
     CDS             14611..15726
                     /locus_tag="PC512_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HDF2441470.1"
                     /translation="MKIIVIKIVIIVKIIIAITTNKIKLKILGGLIQLIIQKKFTIAD
                     GNFERELFGNFDENVKLIEKTLNIDVILREGNIILIGEEKNVDSALKLMNELHQTVSN
                     GKHLDKQSISYSLSLLLEGSEQKIKELEGTIVITQRGKAVQPKTLGQKEYIKLIENND
                     ITFGVGPAGTGKTYLAVAMAVKAFKRDEVSRIILTRPAVEAGESLGFLPGDLKDKVDP
                     YLRPLYDALFEMLGADKFNKYLERGTIEVAPLAFMRGRTLDNSFIILDEAQNTTSEQM
                     KMFLTRLGFGSKAVVTGDVTQTDLPQNKKSGLIQATEILKGVPGIGSIMLTDRDVVRH
                     ELVQRIIRAYEKHDKREEFKKEERKKAKMQEKTFKRK"
     gene            15783..16244
                     /gene="ybeY"
                     /locus_tag="PC512_001725"
     CDS             15783..16244
                     /gene="ybeY"
                     /locus_tag="PC512_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HDF2441471.1"
                     /translation="MDLILDDRQDKLEVSEELIEKIKDIIIECLDYEGYDDNYEVSLS
                     FVDNKEIHELNREYRGVDRVTDVLSFPLLSDDFEDVELEEESLGDIVVSLERALEQSI
                     EYNHSFEREVCFLICHSMFHLLGYDHDTDENTKEMREKEEHILNKLNITRE"
     gene            16250..16969
                     /locus_tag="PC512_001726"
     CDS             16250..16969
                     /locus_tag="PC512_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HDF2441472.1"
                     /translation="MKPEKTRQGIIKAFNAAIEGILYTFKFERNMKIHYLGSVAVLII
                     SLFFNFSKLEMIMLLMSICLVVVAEMFNTAIEKAVDLVTDEYHVLAKIAKDVAAGGVL
                     VAALNSVVVGYILFYDKLTDISGILIYKIRESELHITLICILLVLIAVVVVKALTSTG
                     TPLKGGMPSGHAALAFAIATAITLMTERVVASTLAYIMAVLVAQSRIEGKIHTFWETI
                     AGALLGVLIAILVFQLGMFYN"
     gene            17088..17489
                     /locus_tag="PC512_001727"
     CDS             17088..17489
                     /locus_tag="PC512_001727"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HDF2441473.1"
                     /translation="MDNIELLRLAEDARQHSYAPYSGFRVGAALLTKSGKVYTGCNIE
                     CASLGGTNCAERTAIFKAISEGDKDIYKIAIASDNSENNEQTYPCGICRQVIIEFGSD
                     IKIITGYTKGEVFEHSIKDLLPNYFSGNDLK"
     gene            17553..18446
                     /gene="era"
                     /locus_tag="PC512_001728"
     CDS             17553..18446
                     /gene="era"
                     /locus_tag="PC512_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HDF2441474.1"
                     /translation="MFKSGFVSIVGRPNVGKSTLMNNVVGEKIAIMSDKPQTTRNTIQ
                     AVYTDEEMQIVFLDTPGIHKPKNKLGEFMVKAATEAFKNVDLILFVVDDSKKIGPGDR
                     KIIEDLRSVKTPIILVVNKIDQLDQKDELFDIIKMYDREGIFKEIVPISALKGKNTDT
                     LIKVIQNYLEEGPKYFPDYMITDQPERVLIAELIREKVLHYLNDEIPHGVAVEIEKMK
                     ARNDKEIVDVSAVIYCERDSHKGIIIGKNGRKLKGIGKSARQDIELLLGSQINLQLWV
                     KVKENWRNLQNYINNFGYNDK"
     gene            18458..19837
                     /gene="mgtE"
                     /locus_tag="PC512_001729"
     CDS             18458..19837
                     /gene="mgtE"
                     /locus_tag="PC512_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HDF2441475.1"
                     /translation="MDRKLDASQDLLYEVKSLIDNNKVLELRELIEEYHIIDIFDIME
                     NLEEDMKIQLFEVLPLDMASSILEEGSVEFFISILSKLDVEHSKNILELMSLGDMADK
                     LSELEEEEREHIINLLNQENADYVKELLFYDEDSAGGTMTTGYISINKDMTALEAIDH
                     MREEAEEAETIYYIYVVDDEEKLVGVLSLRELIIARDANIVEDLMSENIISVYVDEDR
                     EEAVRLVSKYNLIAIPVVDRQEKLKGIITVDDIIDVMEEEATEDMYKFAGSSEHEREV
                     AEKENPTLREQIISALRGRLPWLIITLVGGLLASLILSNLDYIMNPVYAPLVFFIPVV
                     IGMGGNIGTQSSSVTVITLSNKDLNFSNVVREGIVGIITGLLCSIITGIVIYFVMRKL
                     DIVLIVSISLFINMVLGATIGAFMPVLLKKMDADPSTVSSPIISTALDITGIAVYFII
                     TTALLSKIV"
     gene            19910..20065
                     /locus_tag="PC512_001730"
     CDS             19910..20065
                     /locus_tag="PC512_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqzL family protein"
                     /protein_id="HDF2441476.1"
                     /translation="MNNISWEVFKKTGSIDAYLYFCDCKNIHEEIEEVREKKEDDDNP
                     EHPGDST"
     gene            20031..20804
                     /gene="recO"
                     /locus_tag="PC512_001731"
     CDS             20031..20804
                     /gene="recO"
                     /locus_tag="PC512_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HDF2441477.1"
                     /translation="MIILNTQGIVLKAIRYKESDIILTLFTRKLGKVSAIAKGAKKNK
                     SSLLSSSQLFSYSNFTLKKQGNMYKVTQSEIIKSFYNISYDIEAFSYATYITKLVENS
                     ILENQTNNRLFILLAQTLYLYTQDNTDNRFITAAFELKFLDYIGFKPIVNKCINCECK
                     ILQNSVFNIYEGGILCSKCSKLFDNNIKLDLTTISLMEYVLRNDILTCSKAKVSKYIT
                     HELENILDKYLKVYVDNINFKSLHVLQSVKNNKGVDNDE"
     gene            20797..21396
                     /locus_tag="PC512_001732"
     CDS             20797..21396
                     /locus_tag="PC512_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4342 domain-containing protein"
                     /protein_id="HDF2441478.1"
                     /translation="MSSNITIEMVDSVFERVPGATYAEAKEALVMCNGDVIEAVIYLE
                     NKKNTCNCKAKSAKETMEEVFGKDGENIKFQLKELLRKSSVVRIIVEKDGKTMMNIPL
                     TVGVVGLAFVPLATLVGLSAAVISKYRIKVQNEEDGEIVDLGELNEEKLHVLKNMITN
                     AAKDVKDVVVDKKEDDKDVTADLMKEESEKNKEDEDENK"
     gene            21556..22434
                     /gene="glyQ"
                     /locus_tag="PC512_001733"
     CDS             21556..22434
                     /gene="glyQ"
                     /locus_tag="PC512_001733"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HDF2441479.1"
                     /translation="MNFQEMILALQKYWSKQGCIMMQPYDIEKGAGTMNPNTFLRSLG
                     PEPWQVCYVEPSRRPADGRYGENPNRLYQHHQFQVILKPSPDNIQELYLESLKEIGID
                     PSEHDIRFVEDNWEAATVGAWGLGWEVWLDGMEITQFTYFQQVGNIECELETGEITYG
                     LERLAMYIQEVDSVYDLKWNDKITYGEVFNKAEYENSMYAFELCDADMLFNLFDIYEK
                     EALRLMENGLVIPSYDYVLKCSHAFNTLDARGAIGVSQRASFIGRVRNMAKTVAETFV
                     KQREEMGFPLLKDGDK"
     gene            22434..24500
                     /locus_tag="PC512_001734"
     CDS             22434..24500
                     /locus_tag="PC512_001734"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HDF2441480.1"
                     /translation="MKNYLLFEIGVEEMPSRFVGSTLEQLKNNLSKLFDENRIAFDKI
                     NAYGTPRRLTLVVEGLSDRQSDLEEEIKGPAKKIAVDAENNLTKPALGFIKSKGLSES
                     DIYFKQVGKEEYIFATIKQDGKETSEVLKDILPETIKSVVFPKAMRWGGKNLKFARPI
                     RWIVALLNDKVLEFDLEGIISSNVTKGHRFLGESTIEVDSIEDYFEKLEKNYIVLDQN
                     KRKEMIRKQCIEVANSLGGEVEFDEDLLEEVTYLVEYPTAFYGEFDVDYIKLPKEVVI
                     TPMKQHQRYFPVLKEGKLLPNFIAVRNGDSYRIDNVKAGNEKVLEARLADALFFYRED
                     TKRNLESYIEKLKTVVFQVKLGTIYDKTLRLEKLSADILDSLGLVDEKADTIRAAKLS
                     KADLVTGMVGEFDELQGFMGKEYAKVGGENDVVSEAIFEHYLPRFAGDILPKTNAGVA
                     LSIADKLDSIAGFFAIGIQPTGSQDPYALRRQALGILSILMDRKVAVDIKILIEHALD
                     NYSELDFNKEEVVEQIMNFFNERVKNLFKDLGIRYDVVDAVLSSDINDVSDMHMRALE
                     LNNWLEKDELVEMLTAFNRVSTLAQKAESDKIDESLLKEDAEIKLYNEFKQVKVKVNE
                     LLKDKKYGIALDEFASLRPVVDNLFDTVMVMDNDEAIKNNRLALLKQVYDTMLGICDL
                     SKIVYK"
     gene            complement(24666..26213)
                     /locus_tag="PC512_001735"
     CDS             complement(24666..26213)
                     /locus_tag="PC512_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite/sulfite reductase"
                     /protein_id="HDF2441481.1"
                     /translation="MDNFKKILLNELPNFKEYSSKFLNGEINKMQYKGFSGGYGVYAQ
                     RDKKSFMIRLRVSAGVLSQYQLNKIYEIAIKHNLDKIHLTTRQAIQLHDLSINSIVDI
                     MEEGIKNDIFTRGGGGNYPRNVGLSPLSGVDPSEVFDVTPYAVATDKYFIKNATTYHL
                     PRKLKVSYSNCYTDTAHCSIQDLGFVATLKNDEPYFRVFLGGGLGKQPKVALELDELI
                     KPKDALYCVEGMIKFFMDYGNYENKNRARVRYMVESLGEELFLEKFKEYYKLEKENGS
                     LELNIEEIDYSKPGVKIDIQDSRLIPQKQDGLYTVYIHPVGGILLTKDLSTLLKELDN
                     VENPMIRLGMTEGLYILNLNGNEAKRILEISKTISCNSQLEQSISCIGVPICQMGIQN
                     SQKMLHEIIDYFRLQNNEEILNKAPKLYISGCLNSCGVHQVGSIGLCGKKKNVDGIST
                     DAFELFVGGSFEIGKTRLGKSLGDFKASDIPEMLYKISDASSGNFYEWVNSNDNILNK
                     ITDKYKI"
     gene            26493..27260
                     /locus_tag="PC512_001736"
     CDS             26493..27260
                     /locus_tag="PC512_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HDF2441482.1"
                     /translation="MGEIINALDRALDIILLLYHEKREMGITEISKAMGVYKSTVHRT
                     LVTLENKGFVIQNAENGKYWLGINLYAIGMVVGEKMSLTEIVKPYTKKLNQEFNEVVN
                     VSILEERAQDSPRSIIIHKEYGSNQLLSVNPSVGSSSECYCSAVGKCLMAFNDSIDFE
                     KYRKTPIHKYTEHTIDNWDDMMLFLAKIKEQGYAIDDEELEHGLTCIGAPILDKNNKA
                     IAAISLSGPTIRMREGDFEYKIKRVIETAKSISELFR"
     gene            27543..27740
                     /locus_tag="PC512_001737"
     CDS             27543..27740
                     /locus_tag="PC512_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF2441483.1"
                     /translation="MEKVKLSVERCKGCYLCIEACKKDAISLSDYTNKKGFVTIKVDE
                     EKCIQCGACYTMCPDLVFEIL"
     gene            27769..28845
                     /gene="vorB"
                     /locus_tag="PC512_001738"
     CDS             27769..28845
                     /gene="vorB"
                     /locus_tag="PC512_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HDF2441484.1"
                     /translation="MQSLLIKGNEALAEGAIRGGCRFYAGYPITPQSEILEMMAWRQK
                     EVGGVFIQGESEIASVNMVMGASALGARAMTSSSGPGFSLKQEGIAYWVSAGLPAVVA
                     CVQRYGIGDGFIGAGQDNYWQAVKGGGNGDYHLIVLAPNSVQENMDMAYESFELAEKY
                     MHPVLILSDATIGQMVEPCIAPPMKEYDMDKAPWAAKGTPVGEKNKVITDITYFEDQD
                     TWQKGYIEKMRKVQEDEQRWEEIEIEDAEVVFVAYGISSRIAEGAVRDARAKGMKLGL
                     IRPKTLWPYPRKAFKKLSDSLKGLVTVEMNMMAQMKEDVIIACDNRFPVYSVATAQYM
                     AEVNQLIDFAQQIIDGKAKQEEVF"
     gene            28848..29567
                     /locus_tag="PC512_001739"
     CDS             28848..29567
                     /locus_tag="PC512_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HDF2441485.1"
                     /translation="MAKKAPAIMMCENMFCGGCGHSIVDRIIGEVLTEMDICQDTIIC
                     SDIGCNHMFQFSMNVDVVVPPHGKMGAAMAAMKRVRPDKYIFTIAGDGGAYAIGLGET
                     MSAATRNDNVIFLVMNNNMFAMTGGQMAPTTIEGQYTASTPAGRNYADHGSTFDVVKV
                     MGNLDIAYLARGTITNPKEINTTKRYIKKALEKQKEKKGFCLIEVLVPCPTNWGLKPV
                     DAMKRIENELVPKYPLGEFID"
     gene            29580..30119
                     /locus_tag="PC512_001740"
     CDS             29580..30119
                     /locus_tag="PC512_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HDF2441486.1"
                     /translation="MLNEIICAGFGGQGVLTAGKIIMYVAYKAEKKITWFPSYGNEMR
                     GGSANCNVVVSDEKIANPCVKNPDILLGMNSVSVDKYESLMKKNGYMFVNESLVSKDR
                     KYREDINVIKVPVTEIAQNLGNEKAANICMLGAMVKSLDLFTKEEFESGMCEYFENQG
                     KGKFNSKNVEAFEAGYDYE"
     gene            30276..31334
                     /gene="buk"
                     /locus_tag="PC512_001741"
     CDS             30276..31334
                     /gene="buk"
                     /locus_tag="PC512_001741"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HDF2441487.1"
                     /translation="MKVLVINPGGTSTKISVFQDENEILKKNITHTREDLKNFSKVFD
                     EYDYRKQLIVDILSSENHSINSFDAVVGRGGLMKAIKGGTYTVSEEMIEDMRNEINGE
                     HASNLGALLAKTIADEIGVQSFVVDPVSVDEFDDVSRITGISDIEKASWLHALNHKAV
                     SRKIAQKLGGKYEDYNFIVAHLGSGISIVAHKQGKMIDGSGGRSDGPFSPERSGGLLA
                     YPLIELCYSGKYTHDEMVAKVSSIGGMYDYLGTKDMIEIENRIKEGDEKAKLIMDAFI
                     YQVAKEISMYGASLSGNVDRVILTGGISHSEMVVKGVAEKVSYLAPIEIVPGEMEMEA
                     LALGALRVLNGEEIAKTY"
     gene            31352..32245
                     /locus_tag="PC512_001742"
     CDS             31352..32245
                     /locus_tag="PC512_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional enoyl-CoA hydratase/phosphate
                     acetyltransferase"
                     /protein_id="HDF2441488.1"
                     /translation="MLKDFNNLLEEAKKLEPVIVSVAVAEDKEVLKAVKSATDLNIIK
                     PILVGDKDKIESISREIGLKGHEIIGCQNPDESVKKAVEIVKNKEAKVLMKGLVNTSV
                     YMRAILNKETGLRTGRLLSLLAVYELPQYHKLLYCTDSGINVSPNLNQKKDIMTNALL
                     TMKSIGMENPKTAILTANEMVDPKIQSTVDANLLVEMEKSGEIPKCIVEGPIAFDVAF
                     DAHAAEHKGIKSNIAGDVDLLVFPNIEAGNILGKSWLRFNKAKWAGIVLGATNPIILG
                     SRSDTAEIKINSIALACLASQ"
     gene            32275..33483
                     /locus_tag="PC512_001743"
     CDS             32275..33483
                     /locus_tag="PC512_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDF2441489.1"
                     /translation="MKYAKRMDMVKASAIRDSQKKIAQKVASGGTVISFAAGLPDPNL
                     FPIEEISEITQKVLNERGKFALAYGPTKGEDELLDLLVKRMKEEENIDTKAENIIITT
                     GSQQGIALSAMILLEKGDVVVTENPSYLGAINAFRPYECDFLGVDTDEEGMVTDDLDK
                     LLSENSNIKVIYVIPTFQNPTGKTWSLQRRKDFMEVVNKYDVIVIEDNPYGEIRFTPE
                     PLPTLKSLDTKDKVLYLGSFSKVLCPGFRVAWMCGNVDIIDKAELLKQGIDLQSNQFS
                     QVQVIEFLKKYNLNEHIEKIRAEYKKRCLLMLDAMKKHFPEEAKYTEPDGGMFIWVEL
                     PESINVDDLLDKAIDAGVAYVSGESFFANNGPKNTMRLNYTTMSEEQIVKGVEILAEV
                     IKKELNYACE"
     gene            33507..34766
                     /locus_tag="PC512_001744"
     CDS             33507..34766
                     /locus_tag="PC512_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2441490.1"
                     /translation="MGEKENGIKFGKLMFQLVIIAISWELVYIIPFIQYTLYDPILKA
                     LECTNTQLGFLLTIYGLGNIFGAPIGGWLADRFDYRKIILGSVFLNGVVSFLFAFNMN
                     YPFAVATWVGCAITSLVMNYPSMVKILRVIGKDNQGKVYGFNEAMVGVSGVVMGAIFL
                     YIYTCFATPTLGMRWVMISLGILSIAMCPVLWFVIKDVDIKEEREEAGEKMSAGDFIT
                     VLKSPNTWLVGISIFCVYSFTVTMSYFTPYITSVLGGSVALSGALAIIRQHGLKLFGA
                     PFGGYCADKLKSPTKVLLPIYVFGIAVIVLFLVLPASTPMTIFIALTFVVGILGYMGK
                     GIYYAVQDEVKVPVKYSATTIGIAAALGFSPDVFQFALIGHWIDTYGNKGYTYTFIFQ
                     IAILVIGILSCLYILKVKKRRASKLEA"
     gene            35411..36874
                     /locus_tag="PC512_001745"
     CDS             35411..36874
                     /locus_tag="PC512_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine:cation symporter family protein"
                     /protein_id="HDF2441491.1"
                     /translation="MTDLVNTINGIVWSPVLVAMCLCIGLYFSLKLKFFQIRDVKEMF
                     TLLLEGDSSHVGISSFQGFATSMAGRIGTGNIAGVAVAIAMGGPGALVWMCIMATLGS
                     ATAFVESTLAQIYKDEHDGQYRGGPPYYFEKGLGWKKCSVLFSIVAIISYTFFMPGTQ
                     SNTLYLAMNQAFGFSKMTIAVASSIALAIIIFGGIKRIGLFAEKVVPIMGGAYLIMTL
                     VIIITNISLVPEAIVTMFKSAFGFGSVFGGMLGSAISWGVKRGIYSNEAGEGSGTYGA
                     AAAEVSHPAKQGLVQAFSVYVDTLLICMATGIMIVITGMYNVTGVCTALPGVEPGPQY
                     VQSAINTLHPQLGDIFIAIVLLLFTFTTLLAFSYMMETNVSYLVTRIKAEKHEKYIIN
                     VCRFMLIACAAMCCFIEPLTSWALGDICIGVLTYINLIAIFTLKKPAIKAYYDYIRQK
                     KMGIKRSDRTFNPIELDIRNAEFWENRYLKEDKHELN"
     gene            36930..38066
                     /locus_tag="PC512_001746"
     CDS             36930..38066
                     /locus_tag="PC512_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDF2441492.1"
                     /translation="MKERIIQVADSKKEKILGLCQSLYDEPEIALQEYKSAKKISEFL
                     REEGFDVEENLAGMATAFKATKKNGDGPKIAFIAEYDALPGNGHACGHHLIASMGVGA
                     GIALSSILDTYKGEVSIIGTPAEETGDGKPYLIEHGVFDGYDAAMMIHPNSKTCVTPE
                     IIAIGGLDFIFTGKASHAGAKPYNGINALDAVVLLYNNINALRQQLVDGTRIHGIILE
                     AGTAANVIPDMGKVRLEIRAKEQNYFDEVVEKVKNCARGAAIATGCELEFYHFEPTCQ
                     GLNENKVLVDIFTKIMEEFGIYEDEQVMLGSTDMGNLSQIMPCIHPLMKFSENGEELH
                     TKEFLEASINSYAKDRVIDGIKILALTGFNLFENPELLKKMKEE"
     gene            38302..39417
                     /locus_tag="PC512_001747"
     CDS             38302..39417
                     /locus_tag="PC512_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HDF2441493.1"
                     /translation="METLEVRNIELSGTNYEIGYRLGELVANMPEIIEGQINKSNLVS
                     KKEEKEMIELFDKYCPGLNEELQGFADAIQVNCNQILYYTMTYLKPGCSQVALAPELT
                     ENGHVLFARNFDFSHNMEDFVLCKTKVNGKYAHIGTTVMQFGRGEGMNECGLGVSQSS
                     CGIPVGNSDGLRKPAIVGLQFWAVIRYLLENCKDVDEALEYLKDMPIAYNINLLLADK
                     SGNIALVETLDGKKEVNIINSLESKREYFLHSTNHTHIDKLHKLEPQSMKNSIHRYKL
                     IKEYINKSKKIGEKELMNLLSSKYPNGLSCNYYNDFFGTLKSIVMDLNIGKFNILWGG
                     LENKWESYYLKNDIKSITQRININIEKAPSDFFDFIE"
     gene            39569..40438
                     /locus_tag="PC512_001748"
     CDS             39569..40438
                     /locus_tag="PC512_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF2441494.1"
                     /translation="MDYLKYFKKAVMYIENNLHENITVNDVAKETGYSYYHLTRLFKS
                     MFGESVGSYIKKRRLVSSTKELLYSDKKVIDIAIGSGFESSEAFSRAFKSIYKVSPIE
                     YRKNRIDVFVGKKKKLELDFMRHLVGNITIKPVIKEIEKIKVIGIKDKVILENNSLPD
                     LWEKFRKVHHIVPNTLPSKRVFGICEAISEIHLVSESMEFNEIIGLEVNSYDVIPNSF
                     VSKTIKEGKYAIFTHTGSLDNLDKTYEYIWGTWFLSSKEELDIRDDFEVYDERFLGPS
                     NVNSQIDIYIPIK"
BASE COUNT        16295 a         4103 c         7489 g        12679 t
ORIGIN      
        1 taatggaaat acagtttaat aaatataaaa agagaaagag ggaattttaa atgaatttga
       61 agaaaaaaga gaaaatagtt aagcctgttt taaagaagct tacagaaata gtattaaata
      121 tattatcaaa aaaaatatta aactatgcta tatatgcaat ttctgttttg atagtaacaa
      181 aagttgttat aaatatagat ttgtacatat ccatattgta ttattagata tcttatagat
      241 ataaaaaatt aatagatata tatctattaa ttttttatat tacaaataga gaataatgaa
      301 ttatactaga aagtaggagg tgaaaatatg agcagaattt caatttttat ggaatcatgt
      361 aatggcaaat ttccaaatga aaattcaatg ttgtcagttt cctttataaa aaatatttta
      421 aatgcagaaa acaaagattt tgctaaaaac atatttaact atggggaaga aagaaaaaac
      481 aataagcaaa taaaggatat aaatacagcc atttacatac caaatcttat aagaagcaaa
      541 aatgagttac ttgttgatgg agatataata ttcaatataa gtttttataa ttattctatg
      601 ttcagtaaat tatacaatgg aattttaaaa gtaaaggagc tagaatataa aggttataga
      661 tttaaaataa aaaatataaa aatacataaa gaacacgaga taaaagaaaa tggtgttata
      721 tttaaaacta tgtctcctat aatagtaaag aataaagaag gtaaatattt agatgtagaa
      781 gattcaaatt atatagaatg tttaaactat atagctaatc taactctgga gagtataaga
      841 ggtagtgggc ttagaaagcc attggaattt atacctctta acttcaaaaa aagagtgtta
      901 aaagaaaaga ttcgtggatt taaagagaga gaattttact atataaatgc ttatgcagga
      961 acattttttt taaaaggaaa tatggaagat ttaaatgcac tgtataaaat gggaattgga
     1021 tatagaagga cggaaaatgc aggaatggtt gatatattaa agtagcgagg tgagagaaat
     1081 aaaagctaaa ttttatagat caggtgatat tgtaagagat attggcattg tttacttttg
     1141 tgaattacta atggatttaa aaaacgaact agaaaaaaat gattataagc taaaatttac
     1201 ttgtgagttg aatagaaatt atttatcttt agaatctgca gaatatatag accctaagta
     1261 tatatctgat tatatattag aaaatcaact ttttaaggta tttaaaaatg ggaaaaagga
     1321 aaccttagaa aaaatattta gtaatataga taatttaaca tatgtaaatt ttattgaaga
     1381 attggataaa tcttctgcaa ctgagaaaca aaaggaaggg attaaaaaag attttaaaaa
     1441 cagaagattt ccatatgtta gaaatagtgg taagtatgga ttaaacacga gtctagaaaa
     1501 tatggaaaaa aatgtaaaaa gaatagtcga tattgtgatt aaatcaaata tagagataga
     1561 tgaaatagat aaacttgatt tgaaacaata tgaagaaaaa gatagtgtat gtaatgtttg
     1621 caatataaat aaaacaacaa aactagatat tgatttaaga gaacgaaagg actctaagta
     1681 taacttttta tttagaggtg cagaaaaatc aggttttaaa agaagtggac aagttgaaag
     1741 taatatttgt tttgagtgtg aatttttcaa cttaatgtgt cttttatata taaatttaaa
     1801 aagaccaatg gtttttgcat atacgaatga tttaagagaa ttagcatttt taaatcataa
     1861 gataatgctt aaaagaaaaa tgtattcaga taaatcattt tataaaaaac ttttgcatga
     1921 aaaaataagt tcaattagac tatataggat tgatattgat acgaataaag gtataattct
     1981 aaaatttgac tctattatag agtataaaga attattaaaa aaaattgaac ttatagatat
     2041 tatagataat tataattttt caagagagcc aatgaatact agaaatttgg gtaaaaaaat
     2101 gattaataat gggaatttat caaatttaaa agaattatta cttgataata taagtgtttt
     2161 aaggcaacta actggaactt ctcgagaaat ggattttgta tctagttcat ataatatcgg
     2221 tttatatata aaattgtgtt ggattgtaga tggaagggag gagtataaaa tgaaaaacta
     2281 tatagaaagt aatttaatat attcaagagt aggtaaagac ttatttaata aaatgacaga
     2341 tgaatccaga agaaaaaatt tttctatgaa agtgattcaa ctacttaagt ctaatgatag
     2401 aactcagcta tttcaaacta taatgcatgt gttagtttct aatggaatct taataggaga
     2461 agggtttgta gaaggtctaa tgcagagttc tgaattagaa ttaaatacga atgtaggtct
     2521 atttattcaa gaaatcatga aataaaaaag ggggaaaatt taaaatgaat gaaaaaagag
     2581 taaaaggagt aacattaact atactgacag aaagcccagt tccactttcg tatgaccaag
     2641 ggtatggaaa ttatacacca ataaaaaaag aacaatatag agataaagta catgcaaaaa
     2701 ctagtatagc tacaataaca tatgatttaa gaagaatact ccatcaagaa tatggttgga
     2761 atttaagtaa tattgttttt ggaaaaaaag gaaatatata tccatctatt aagaaaaatg
     2821 taggatgtgt agatgaaaat ggattagaga ctgatgtatt tggttattta ataccactta
     2881 aagagaaagg ttctataagt aaggcttctc cgcttagaat aatacctttt aggtcactaa
     2941 attcatatag aggttcaaca cagttgataa caaatagagg ttttttaagt agcgaatttg
     3001 gtagaaaata ttatgatgag agggaagaaa atgaagtact tagagatgaa aactttccaa
     3061 caacacaagc attagcaata gaagagactt tatcagatta ctacgtttat acaataacat
     3121 tggagcttga tagaatagga gtagtagaag tagaagaaga tggaaagtta cttttaccag
     3181 aagaaagaaa atttatgagt aaggagttaa gagaaaaagc agtaaaagat atattagatg
     3241 caattactgt gtttacaaga aacataaaac attcatcagt actattaaaa ccacttgcag
     3301 taatgggtgg agcttttgat aaagttgtac catttttttg ggatgatgta gattataatg
     3361 ctgatagtgg tgagataaat ttagagggag tcatagaaac tatagaaagt tatagcctta
     3421 aagaaagtaa cacaatactt gctatcaatg acagattaaa aatttctaat aaaaaggaat
     3481 taaataagtt taatttaagt aaataccctg taaaagagat taaaaatcta gcagatagat
     3541 tggaaattgg agaagataat atgtggtatt taaaagagta ggaggttttt tgaattatga
     3601 aagtattaca atgtaaactt aagcaaccaa ctgctcacta tagagaccca aaagtatttc
     3661 aaaatgaata tataagtact ttaaatttac catctaagac cacaataatg ggaatgataa
     3721 cgtatttatg tgatagaaga ttaaactctg atatagatat aggaataatt ggaacacatc
     3781 atcatagaga actagaattt tcaagaggag agaacattga tttttggaat gaatatacaa
     3841 atatgagaaa aggcaaagat aaagaaaagt ttttgcttca aggaaactac tatgattact
     3901 ataaagaaca taaagctcaa aatagcatat taaactatga agttcttaaa gaagtagaac
     3961 tgactatatt tatttcttgc aaggatgatg aagaacttga atttattaga aaaaagcttg
     4021 aaagtccatg taaatatgca aatttaggaa gaaaagaaga ttttgtaata ccaagtgaaa
     4081 aagggtgttt tgtgaaagaa gttgagttaa aagaggttat acctatgaat actcgtgatg
     4141 ctataaaaga aaatataaaa ttaaagaata catatgtaag agttgactta agagataaag
     4201 agaatgtcga gactataata aatcaaggtg tattgattgc attaccttat aaatataaag
     4261 atttagaagc aaatagagat gatagagttt atgagttttg ccattatata tatgttgata
     4321 atgatggtat atatcctaaa aatattaagg taaatgtatg tattgataca aaagaagttt
     4381 ttacatggct ttaaattatt ttgaaagata ggtgtttatc atgaaaaata tcatgcaaaa
     4441 agaaatatta gctaagtcat ataatttaag aactaatcaa caagagcaaa cattagttga
     4501 acatattaag gatttatttg aagtattaga atctatatta gaactaaatc tatattcaga
     4561 taaagatgta gagatactaa aaatatgttg tgctttgcac gatttaggaa aaattaattc
     4621 aattatgcaa caaaaaatgg agattaataa taaaatatcg tatagttgct cagaagaaga
     4681 gaggaaaaag ttagagtctg acaaaaaatc tttaaaaaag atagcaagac ataatatatt
     4741 ttctggagca tttttaaaag atatattaga aaaaatgaac ttgtcagaag aagataagtt
     4801 atatatatat aaaagtataa tgttacatca tggaaactat gaagattata tgaggttaag
     4861 tattagtaaa gttcaagaag aaatttatga gtatattgaa aaaggcattt tagaaaaaga
     4921 agagtttaat ctgaaagata tagaaagtta tataaatagc attttaaatg tagactttaa
     4981 atttggtgaa gatgtattgg attatgatta catagataaa ttaagtgaaa gtatgtttat
     5041 agacagtgat tataacaatg gtcaaataga tgattcagtt ttaaattata gaaagtttaa
     5101 gtatatttta tataaaggga tgctgaactt aatagaccat agtgcatcaa gtagacagaa
     5161 aggtataaaa ttttataacg attttactga tgaagaaatt gataatatga ttttaaatga
     5221 gatatataag agtcagggta atttggaaaa aaataatata gagttcaata ctatacaaaa
     5281 aaggttgaga gaactttctg gaagaaatgt tctgactgtt gcatttacag gttcaggaaa
     5341 aacagctgca gattatagaa agacttttaa aagaaaattc tttttagtgc caaataaaat
     5401 atcagcagaa agtttttata gaaaaaatat ttttcaaaat aaaaatgatt tagatacaag
     5461 aagtagtaat gattacattg gattacttca tggagatata aacttatatt cagagaatga
     5521 agataatgga gaacatgatt ttgtattgac attaagggat atagatttga gtataaactt
     5581 ttgtaaacct tgtgtaattg caacagttga ccagttatta cttagtatgt ttaaatttcc
     5641 gggatatgaa aaaatattcg cagccgtaaa aaatgcatct ataactgttg atgaagtaca
     5701 tttattggaa ccaaagatgt ttttgatttt gatatatttt atgcagtttg catgcaagta
     5761 cttagatgtt gattttcact taatgacagc tacacttcca aaatcatata aagagcaaat
     5821 gataaacaag ggaattattt ttcaagaaga aagtaatgaa aatgttactg ataaaggaga
     5881 aatagttttt attgagagca acaaggaaga agagatttgt gaaggtaaag atgtaaaggt
     5941 ttcttttata aaggaaaaag aaatcaagtc aatagttgaa gatgctttag aaaataaaca
     6001 aaaaattctt ataataaaga atactattga ttcagtcaat agaacatatg agtttttaaa
     6061 agaaaattta tctgataagt atggtggtgt agatatagat gttttacata gtagatttaa
     6121 gttcaaagat aaaaaagaga aatatagtaa aatattaaat ggagagggtg atatttggat
     6181 atcaactcaa tcagtagaaa tatccttgga tttggatttc aatataataa taagtgattt
     6241 agcaactatg gatagcttga tacaaagaat gggtagatgt aatagaaata ataaatatga
     6301 atatggaaac ttttatattc tacctagtga agataaaatt tatgataaca aacttaagaa
     6361 cacaactaaa aacatcttaa aggacatatt aaaaactaac tctattttta caatgggaat
     6421 tagaaaaact attttggatg attactatga taatagtgta gtcaaaaaat attttgaaga
     6481 gaattttata agttgtgata aagaaattaa gaatatttat ggtataaata aagaaatttt
     6541 tgatggattg gatttaattt ttaattttga accttacaaa aatattgttg atagtaagaa
     6601 ggaagcagct aaaattttta gagatgttga tgttagttac aaaattattc tggaagaaga
     6661 tttttataag gaagatagag agttacaaca agattcgatt caagtatcag ggtttatatt
     6721 taatagatta tattattatg ggttaataag caaagtagaa ggatacatgg tactaaaatc
     6781 tagtagtaag tttgagtata atagtactgt aggcttaatt ttgaagtgag catatgttta
     6841 aatataatat acctttagac attgaaaata caaaaagtac tactgtaagc tcactgtaaa
     6901 aactattttt ttaaaaggaa aaataagttg tgagatagag tgtttacaag tgtatataga
     6961 taataaattt gaggtttaag attaactaag tgggtttcag gtacatcgcg aaaataatta
     7021 taagttggag attttgtatg tttaagatta actaagtgga tttcaaatat tgatatagta
     7081 gatataatag aagttttatt attaggttta aaattaacta atcggatttt taaatattct
     7141 gactattata taaggatatt attagcttga atttaaaacc aataatataa aacaacaaaa
     7201 tattatattt atgatataat aaaagttatg gaaaaacagg aatattacta tagagaagag
     7261 aggtaaactt atgaataatt ggatagaagt aactataaaa acaacaacag aagcagttga
     7321 acctataacg aatatactat atgaacaagg agctggagga gctgtaatag aagacccaaa
     7381 agacttttta ttccaaaaga aaaatgaact agactgggat tatgttgaag aagaagtatt
     7441 taaaaagaat gaagaagatg atgttcttat aaaaacttat gtttctgaag aaaaaaatgt
     7501 gatggaattt gtcgaaataa taaagcaaaa agttttaggg ttaaaagatt ttggtataga
     7561 tataggtgaa ggaagtgtat cattggacca agtaaatgaa gctgattggg caaatgcatg
     7621 gaaagcatac tacaaaccaa caaaagtagg acaaagggta gtagtaaagc ctacatggga
     7681 agattatgct atgcaagagg gggatttaat catagagctt gaccctggaa tggcatttgg
     7741 tacaggtaca catgagacta ctagtatgtg cattagagaa ttagaaaagt acgtgaataa
     7801 agattctaaa gtatttgata ttggctgtgg tagtggaatc cttgcaatag cagcagctaa
     7861 attaggagca aaagaagttg tagctgtaga tttagatgaa gtggctgtaa aagttgcaaa
     7921 agaaaatgtt cttgaaaata aagttgaaaa aagtgtatct gtaatgcatg gtaatttaac
     7981 tgatgtaata aaagataaag cggatgtaat agttgcaaat ataatagctg atataataaa
     8041 gatacttgca aaagatgttc aaaactttat gaaagaagat gctatattca tatcttcagg
     8101 tataattttg gataaagtag aagaagttaa agaaagctta attgaaaatg gatttgaaat
     8161 agttgaagtt caaaaattag gtgaatggtc agcaatagtt tctaagctta aaaaataagg
     8221 gatatggtga cgtataatgg atagattttt tgttgaaaaa aataatataa atctacaaga
     8281 taaaacttgc actatagaag gtgaagatgt aaaacatatt tcaaaagttt taagatgcaa
     8341 attaggtgag aaacttgaaa tatgtgacaa gaataataat gagtatattt gtgagataat
     8401 gaatatagat aagagtatag ttaatttaga aattttagaa aaagttgata taaatagaga
     8461 atcagaactt aaagtaaggc tataccaggg acttccaaaa gctccaaaaa tggaaatgat
     8521 acttcaaaaa ttaactgaag tgggtgtaga agaaataata ttagttcaaa ctaagagaag
     8581 tgttgttaaa gttgatgaca aaaaagaaga taaaaaattt gaacgttggg aaagaataat
     8641 ttatgaagca gcaaagcaaa gcaaaagagg taagatacca aaattaagag gtgttttaag
     8701 ttttaaagaa gctttagaag atatgaaaaa aaataatgta aatatttgcc cttatgaaaa
     8761 tgaaagaaca gtttcaataa aacatgcact aaaaaaatgt gattctaata tagatagtgt
     8821 tggaattttt ataggtccag aaggtggatt ttctgaagaa gaaatagaac aaatacaaaa
     8881 aaataattgt aatgttgtat cattggggcc tagaatatta agaactgaga cagcttctgt
     8941 tgtagcatca acaatagctt tgtatgaact aagtgattta ggaggagaaa aataaattga
     9001 aaaaagtagc tttttataca cttgggtgta aagttaatca atatgaaaca gaagctatgc
     9061 tagaactatt tgagaaagat ggttatgaac aagtcaatag tgaagagtat gctgatgttt
     9121 atgttataaa tacatgtaca gttactcata tgagtgatag aaaatctcgt caatatataa
     9181 gacgagttaa aaagaagaat ccagatgcaa taatagccgt tgtaggatgt tattctcagg
     9241 tatctccaga agaaattttg gatatagaag aagtaaattt agtcatgggc acaaatgata
     9301 gaagaaagat tgttgaagaa attaaaaaga taaattcaag taagaaagtt agtacagttg
     9361 atgacataat gaaagttaaa gcttttgaag aaatagaaat cagccaaact aatggaaaga
     9421 ctagagcatt tatgaaaata caagatggat gtgacagatt ttgtacttat tgtatcattc
     9481 cttatgcccg aggacgcgtt agaagtagag atattgatag tatagtcgat gaagtgaaaa
     9541 aattggctaa taatggctat aaagaggttg tattaacagg aatacatgtt gcctcttatg
     9601 gaaaagattt aaaggatagg gatattaaac ttcttgatgt aataaaacaa ataaaccaga
     9661 tagaaaaaat agaaagaatt aggcttagtt ctgttgaacc aattttattt acagatgaat
     9721 ttgtaaatga agttttaaag atggataaag tttgtcctca ttaccattta tcacttcaaa
     9781 gtggatgtga tgaaactcta aaaagaatga atagacgata cacaacttta gagtacaaaa
     9841 ctattgtaga tagattgaga agtaaaatgc cagatgtggc aataactaca gatgtaatag
     9901 taggttttcc tggagagaca aatgaagagt ttaaaaaaac gtacgagttt ttaaaagaaa
     9961 tagagctttc acaaatgcat atttttaaat attcaccaag aaaaggaact ccagctgcaa
    10021 ctatggaaaa tcaagttgac cctcaaatga aacactttag aagtgaacaa cttttaaatt
    10081 taagtaaagt aaattttaat aaatttgcaa ctaaatttat cggccgtgag ttggatgttt
    10141 tatttgaaca aaatatagaa ggcaataaat atgagggatt aacttcaaat tatataagag
    10201 ttgttgttga aagtgacaaa aatatacaag gtcagatatt aaaagtgaaa ataaatgatg
    10261 taaaagatga atatgtagaa ggaattttgc tataacatgt agaaattata atatttataa
    10321 gataggaggt ggaaagaatg gattgtattt tttgtaaaat agcgaacgga gaaatacctt
    10381 caactaaagt ttatgaagat gatagagtct tagcttttaa tgacttgaac ccagttgctc
    10441 catatcatat attagttgta cctaaaaaac attatgatag tttaattgat attcctgata
    10501 aagagatgga cattgtgtca catattcatg ttgttattaa taaaatagct aaagagaaag
    10561 gttttgacca aactggattc agagtcataa ataattgtgg aagtgatgga gggcaagaag
    10621 ttaaacattt gcactatcat attttagctg gtaaaaagct tcctaattac gaagcgggac
    10681 aaaactaaac taaattattg aaaaattgag ttccttcttg ataaaaatac ttgataaaag
    10741 taaaaattta gtttataata aacaaagtgt taggttgtaa tgcatattat gcaaaaagaa
    10801 catagttaca gtcccagcat aattgcgcta ttggagggag ggaaaaagaa atgtcagaag
    10861 taagagttag agagaatgaa acattagaca gcgctttaag aagattcaag cgtcaatgtg
    10921 caatgtctgg catcatgtca gaagtgagaa aaagagagca ctatgataag ccaagcgtta
    10981 agcgtaagaa aaaagctgaa gcagcaagaa gaaaaaacgc taagaaatag tagtaaataa
    11041 gaataaagag gtgaagggga tgtcccttaa gcaaaagtta caagaggatt tgaaatcttc
    11101 gatgaaaaac aaagatacag tgagaaaatc tgtagtaact ttaataagag cttctataaa
    11161 gcagtatgag gttgataata gggtcgagct tgatgaagat ggaattatcg atgtaatagc
    11221 aaaacaatta aagcaacgta gagatgcatt agttgaattt gaaaaagctg gaagagaaga
    11281 cttaataaaa gaaacagaag gtgaaattga agttttaaaa gagtacctac ctcaacaatt
    11341 aagcgaagaa gagttagaag aaattgtaaa atctactata tctgaagtag gggcaacttc
    11401 tatgaaggat atgggaaaaa taatgtcagt tatccaacca aaagttaaag gaagagctga
    11461 cggaaaactt ataaataagt tggtaaaaca aaacttacaa tagattgata tagcctagag
    11521 agaaatctct aggcttttta tagtttttgg gaataacgag tcatatttga gcatatctat
    11581 aatcaaagaa aattttgaaa gaaggggaaa aatttgatta tatcagtaaa agagattagg
    11641 aattttttga taaacatatt tataccacta ataataggtt acttaagtag catcttaaca
    11701 atgattatca gtggaacaga tatttcaacc tattatttac aactcacaaa gccaagcttt
    11761 gcaccaccag cttttatctt tcctatagtt tggactatat tgtacatatt gatgggtata
    11821 tcttcatacc taatattaag aaagggttac aacttaccta aagtaagaga tgcaattttt
    11881 tattatggat tacaacttgt attaaacttt atttggagta tactattttt tggatttgga
    11941 cttagattta cagctttgat agatataata ataatgattt tggtttctat aataatgatt
    12001 tcgaagtttt ctaaaataga taagagatct ggatacataa atttgattta tttaatgtgg
    12061 cttgtttatg caggattttt gaactatttt atatggttta ttaataaata gaatgtaaag
    12121 attttgtaaa ttaccctgta cttttaataa tatcataaca aacgaaaaat aaatagacta
    12181 ttaaaaataa tcattttcat atacaataat attaatttaa atacaataaa tttataaaaa
    12241 ttgtatttaa agattaacat attaaagtat tagaattgga aaggcttgaa gggagaggtt
    12301 tttatgcaaa taatagtatc tgggagacaa atgaaattaa ctgacggaat aaaaggatac
    12361 gtagatggaa aattaagtag gttagaaaaa taccttgatc ctgaatcaga agtgaaagta
    12421 acagtaagtg cgaaaaagga tagacaaaaa gtggaggtta caataattcc tattaacggt
    12481 caaataataa gagcagaaga cgtagaagat gacttatatg cagcaattga tattgtttgt
    12541 gacaaattaa gtagacaagt tgtcaaatat aaaactaaag ttaaagacaa agttcaaaat
    12601 aataagagca taagatttga aaatcttgac tttatagata atagcagtga atttgatgat
    12661 tatgattatg atgatgaaga agatgagaat atagtaatag aaagaagaaa gaaatttaat
    12721 gtaaaaccta tgagttctga ggaggcgata cttcaaatgg aactagtagg acacaatttc
    12781 tatatgttta gaaaccaaga taattttgaa ataaacatag tgtataagcg taaagctggt
    12841 ggatatggtt taatagaaca agattaataa aaattgtata cgtttagatt ttatataaga
    12901 aaaaataaaa aggtaatcat gttgattttt tatcaatatg attacctttt tcttgtttaa
    12961 ataatatatt agatattagg tatttattat ataaaaattt taaaactaat ctgttacaac
    13021 atcaataaag tgcataaata cctatttcaa gcataaaatt aattaagggg gtaatgctta
    13081 tgttagaaat atccactgat ttacaagtaa atcaaccagt tattactgtt acaagtaata
    13141 cgtttattag tatagaaaat tatctatcaa tattagaata tgaagttgat ttaataagaa
    13201 taaagactaa agttaaaaca attaaaatat ctggggataa actttcactt aagtatatta
    13261 ctgatagtga gataggtata aaagggatta tctacaatgt tgagtatgtt gattaggagg
    13321 agatacactt gataagtttt ataaggggat actatgttat agttgtggaa ggagtaggac
    13381 tcgaacaatt tttaaatcat cttataagaa atgggataag tgtttacaat gtaactagaa
    13441 taaaaaatac taaaatggag tttcatatag atagacaaga tataaaagaa tttaagaatg
    13501 tttatagagg aagtaagttt gatataaagg taaagcaaaa aactggggtc ccttttatta
    13561 tcaaaagagt ttataagcac aaaggtatgt ggatttgtgc tcttgtttct ttatttttat
    13621 tgatgtctac atcacagttt gtgacagatg tatatataca atctcctgaa ggtataaaaa
    13681 aagaagctct tagaaatgag ctttataagg ttggagtaag accaggagtc tataagaaga
    13741 gtattgatag aaaagaagtt agagaccata tgatgtcaaa atttaatgat gtggcatatt
    13801 tatctatcaa tgtaaaagga acaaatatat ttgttactgt tacaaaaaag gcagaatccc
    13861 taaaatctac agaccaatca aattattgta atgtaattgc tttaaaaaat ggtataatag
    13921 aaaaggtaat ccctagaagt ggtaaatcag ttattaaatc tggagacata gtccaaaagg
    13981 gagatgtctt attaaatgga gctaatacca agtcaatacc agaagtatgg gcaagtactt
    14041 tttatgagtc cacaaaaaag gcaagttatg tagatactgt aaataaaaaa actggagaaa
    14101 agaaaaatat atatacacta agtttttatg ataaagagtt tacaatgaga aaaaatataa
    14161 aatataaaga ttatgttgtt gaaaataaag aaaaaaaact atcaatagga aactatactt
    14221 ttccaataaa gataaaaacg agtacttttt atgaaacaaa aaaggttgaa gtaaaaagga
    14281 ataaagaaga gttaaaaaaa gaattatctg aaaaagcttt aaaagagtta gaatacataa
    14341 tcccagcttc ggctagaata atagatgtaa aacataactt taaggttaat aaaaatatgt
    14401 tagaatattt aataacagtt caaactagtg aaaatattgc taaaatttat cctcttagta
    14461 agtcagaagc agaaaggttt ataaaggaag aaagtaaacc agatgaaggt gaagaggaag
    14521 ttccttccaa tccagaaaaa agaccattaa atgatataag aaatgagttt gatgaggata
    14581 ataaggataa taaagatcaa aacaattctg atgaaaataa tagtaatcaa aatagtaata
    14641 atagtcaaaa taataatagc aataacaact aataaaatta aacttaaaat cttaggagga
    14701 ctaattcaat tgataataca aaagaaattt acaatagcag atggtaactt tgaaagagag
    14761 ttatttggca actttgatga aaatgtaaaa ttaatagaga agactttaaa tatagatgta
    14821 atacttagag aaggcaatat aattttaatt ggagaagaaa aaaatgtaga ttctgcatta
    14881 aaacttatga atgaattaca ccaaactgta tcaaatggta agcatttaga taagcagagt
    14941 atttcttatt cattatctct tttgcttgaa ggaagtgaac aaaaaataaa agaacttgag
    15001 gggacaatcg tcataactca aaggggaaaa gctgttcaac ctaaaacttt aggtcaaaaa
    15061 gaatatataa aacttataga aaataatgat ataacttttg gtgttggacc tgctggaaca
    15121 ggaaagactt atcttgcggt tgctatggca gtaaaagctt ttaaaagaga tgaagttagt
    15181 agaattatac ttacaagacc agctgtggaa gcaggagaga gtctaggttt tttaccagga
    15241 gatttaaagg acaaagttga cccatattta agaccactat atgatgcctt atttgaaatg
    15301 ttgggtgctg ataaatttaa taagtattta gaaagaggta ctattgaggt tgcaccactt
    15361 gcatttatga gaggtagaac acttgataat tcatttataa tattggatga agctcaaaat
    15421 actacttctg aacaaatgaa aatgttttta actagacttg gatttggctc taaagctgta
    15481 gttacaggag atgtaactca aacagattta ccacaaaata agaagagtgg tctaatacaa
    15541 gctacagaga ttcttaaagg tgttccaggt attgggtcta taatgctaac agatagagat
    15601 gttgtaagac atgagttggt acaaagaata ataagagctt atgagaagca cgacaaaaga
    15661 gaagaattta aaaaagaaga acgtaaaaaa gcgaaaatgc aggaaaagac tttcaaaaga
    15721 aagtaaaagt gtagtaatat agatatatag cattattaat gaataaaaag taggtgtagt
    15781 gaatggattt gatactagat gatagacaag ataaattaga agtaagtgag gagttaattg
    15841 aaaagataaa ggatataatc atagaatgtt tagattatga aggatatgat gataattatg
    15901 aagtgagtct ttcttttgta gataataaag agattcatga attaaataga gaatatagag
    15961 gagttgatag agtgactgat gttttatcat ttcctctttt aagtgatgat tttgaggatg
    16021 ttgagttaga agaagaatcc ctaggtgaca tagtagtatc tcttgaaaga gccttagaac
    16081 agagtataga gtataaccat agctttgaaa gagaagtatg ttttttaata tgtcatagta
    16141 tgtttcatct tttaggttat gaccacgata cagatgaaaa tacaaaagaa atgagagaaa
    16201 aagaagaaca catattaaat aagttaaaca taacaaggga gtagttttta tgaaaccaga
    16261 aaaaactcgt caaggtataa ttaaagcatt taatgcagct atagaaggga tattgtatac
    16321 atttaaattt gaaagaaata tgaaaataca ttatttaggt tcagttgctg ttcttataat
    16381 aagtttgttt tttaactttt caaaattaga aatgataatg ttacttatgt ccatatgctt
    16441 agttgtagtt gctgaaatgt ttaatacagc tatagaaaaa gctgttgatt tagtaactga
    16501 tgaatatcat gttcttgcta agatagcaaa agatgttgca gctggaggcg ttctagtggc
    16561 agcactaaat tcagtagtag ttggatatat tttgttttat gataaattga cagatatatc
    16621 tggaatatta atttataaaa taagagaatc agaattacat ataaccttga tatgtatatt
    16681 attggttctt atagctgttg tagttgtaaa agcattgact tctacaggta ctcctctaaa
    16741 aggaggaatg ccaagtggtc atgctgcctt agcatttgct atagcaactg caattacact
    16801 tatgactgaa agagttgttg cctctactct tgcatatata atggctgtat tagttgccca
    16861 aagtagaatt gaaggaaaaa tacatacctt ttgggagact attgctggag ctttgttagg
    16921 tgtgttgata gctatattag tatttcagct tggaatgttc tataattaaa ataaatgtac
    16981 ataaaatatt taaaataaaa caaatctgtg ctaattaaat ttttatgata taatgtagag
    17041 tattaaataa aaataacttt taattattgt atacaggagg agttgttgtg gataacatag
    17101 aattgttaag gttggcagaa gatgccagac aacattctta tgctccttac tcaggtttta
    17161 gagtaggtgc agctctttta actaagagtg gtaaagttta tactggatgt aatatagaat
    17221 gtgcatcatt aggtggaaca aattgtgcag aaagaacagc tatttttaaa gcaatatcag
    17281 agggtgataa ggatatctat aaaatagcta tagcaagtga taactcagaa aataatgagc
    17341 aaacatatcc atgtggaata tgcaggcagg taattataga gtttggttct gatataaaaa
    17401 taataacggg atatactaaa ggagaggtgt ttgagcatag tataaaggat ttgttgccaa
    17461 actatttctc tggaaatgat ttaaaataaa tttaaaagta taaataaatt taagtaatta
    17521 aaacaagaag ataaaaagtt aggagacagt taatgttcaa atcaggtttt gtcagtatag
    17581 tgggtagacc aaatgtagga aaatctactt taatgaataa tgtagttgga gaaaaaatag
    17641 ctataatgag tgataagcct caaactacaa gaaatacaat acaagcagta tatacagatg
    17701 aagaaatgca gatagtattc ttagatacac caggtattca caaaccaaaa aataaattag
    17761 gtgaatttat ggtaaaggca gcaacagaag cttttaaaaa tgtagattta atattatttg
    17821 tagttgatga ttctaaaaaa ataggtcctg gagatagaaa gataatagag gatttaagaa
    17881 gtgttaagac accaataatt ttagttgtaa acaaaataga ccaactagac caaaaagatg
    17941 agctatttga tataatcaaa atgtatgata gagaaggcat ttttaaagaa atagtaccaa
    18001 tatcagcatt aaaaggaaag aatacggata ccttaataaa agttatacaa aattatttag
    18061 aagaagggcc aaagtatttt ccagattata tgattacaga ccagccagaa agagtattaa
    18121 tagcagaact tataagagaa aaagttcttc actatcttaa tgatgaaata cctcatggtg
    18181 tagctgttga aattgaaaaa atgaaagcga gaaatgataa ggaaatagta gatgtatctg
    18241 ctgtaatata ctgtgaaaga gattcacata agggaataat aataggaaaa aatggtagga
    18301 aactaaaagg aataggtaag tcagcaagac aagatataga attgctttta ggttcacaaa
    18361 taaatcttca attatgggtt aaagtcaaag aaaattggag aaatttacaa aattatataa
    18421 ataattttgg atataatgat aaataaaggt gggttatatg gataggaaac tggatgcttc
    18481 ccaagattta ttatatgaag taaaatcatt aattgataat aataaagtat tggagttaag
    18541 agaattaata gaggaatatc atataattga tatattcgat ataatggaaa atttagagga
    18601 agacatgaaa attcaattat ttgaagtact tcctttagat atggcatctt ctatattaga
    18661 agaaggtagt gtagagtttt ttattagtat tttatctaaa ctggatgtag aacactcgaa
    18721 aaatatactt gaacttatgt ctcttggaga tatggcagac aagttgagtg aacttgaaga
    18781 agaagaaaga gaacacataa taaatctttt gaatcaagag aatgccgatt atgtaaaaga
    18841 gttactattc tatgatgaag attctgctgg tggaacaatg accactggat atatttctat
    18901 aaataaagat atgacagctc ttgaggctat agaccatatg agagaagaag ctgaagaagc
    18961 tgaaactatt tattatatat atgtggttga tgatgaagaa aaactagttg gagtattgtc
    19021 attaagagaa ttaataatag ctagagacgc aaatatagta gaagatttga tgagtgaaaa
    19081 tataatctct gtttatgtag atgaagatag agaagaagca gtaagattag tatctaaata
    19141 caatttaata gcaattccag tagtagacag acaagaaaaa ttaaaaggaa taataacagt
    19201 agatgatata attgatgtaa tggaagaaga agcaactgaa gatatgtata aatttgcagg
    19261 aagttcagaa catgaaagag aagttgctga aaaagaaaac cctacattga gagagcaaat
    19321 aatatcagca cttagaggac gattaccttg gttaattatt accttagttg gagggttgtt
    19381 ggcttcgtta atactttcta acttagacta tataatgaat cctgtatatg ctccattagt
    19441 attttttata cctgtagtaa ttggtatggg tggaaatatt ggaactcaat catcatctgt
    19501 tacagtaata acattatcta ataaggattt aaattttagc aatgtggtta gagaaggtat
    19561 tgtaggtatt attacaggtc ttttgtgtag tataataaca ggtattgtaa tttactttgt
    19621 tatgagaaag ttagacattg tattaattgt ttcaatatca ttatttataa atatggtttt
    19681 aggtgcaaca ataggtgcgt ttatgcctgt tttattaaaa aaaatggatg cagacccatc
    19741 tacagtttca tcaccaatta tatctacagc tcttgatata actggtatag cagtttactt
    19801 tataataaca acggcattat tgtcaaaaat tgtttaataa ctttatgtat gatttatcct
    19861 cttcttacta aaaatataag tataaatgta agaagggggt tttttaaaaa tgaacaatat
    19921 cagttgggaa gtttttaaaa aaacaggtag tatagatgca tatttatatt tctgtgattg
    19981 caaaaacata catgaagaaa ttgaagaagt aagggagaaa aaagaagacg atgataatcc
    20041 tgaacaccca ggggatagta cttaaagcta taaggtataa ggaaagtgat ataatactta
    20101 cactatttac aagaaagctt ggaaaagtat ctgcaatagc aaaaggagct aaaaaaaata
    20161 agagctcttt gctttcatca tcacagttat tttcttatag caattttacc ttaaaaaaac
    20221 aaggtaatat gtacaaggtt actcaaagtg aaataataaa aagtttttat aatatatcct
    20281 atgatataga ggcattttct tatgctacat atattacaaa attagttgaa aattctatac
    20341 ttgaaaatca gactaataat aggctattta tattacttgc gcagactctg tatttgtata
    20401 cacaggataa tacagacaat aggtttataa cagcagcatt cgagttaaaa tttttagact
    20461 atataggatt taaacctata gtaaataaat gcattaattg tgaatgtaaa attttacaaa
    20521 attctgtgtt taatatctac gaaggtggta tactatgtag taagtgtagt aaactttttg
    20581 ataataatat aaaattagac ttaacaacta taagtcttat ggaatatgta ttaagaaatg
    20641 atattttaac atgtagtaaa gctaaagtat caaaatatat aacacatgaa cttgagaata
    20701 ttctagacaa gtatttgaaa gtttatgttg ataatattaa ttttaaatca ttacacgtat
    20761 tgcaaagtgt aaaaaataat aagggagtgg ataatgatga gtagtaatat aactattgaa
    20821 atggttgatt cagtctttga aagagttcca ggagcaactt atgcagaagc aaaagaagca
    20881 ttagtaatgt gcaatggaga tgtaattgag gcagtaatat atttagaaaa taaaaaaaat
    20941 acttgtaatt gtaaagcaaa atctgctaaa gaaactatgg aagaagtatt tggcaaagat
    21001 ggagaaaata taaagtttca attaaaagag cttcttagaa aaagtagtgt agtgagaata
    21061 atagttgaaa aagatggaaa aactatgatg aatattcctt taacagttgg agttgttgga
    21121 ttagcttttg taccattagc tactttagtt ggattatcag ctgctgttat aagtaaatat
    21181 cgtataaaag ttcaaaatga agaagatgga gaaattgtag atttaggtga attgaatgaa
    21241 gaaaaacttc acgttttgaa gaatatgata actaatgcag caaaagatgt gaaggatgta
    21301 gtagttgaca aaaaagaaga tgacaaagat gtaactgctg accttatgaa agaagaatct
    21361 gaaaagaata aagaagacga agacgaaaat aaatagatat aaagtgactt ttaaaaaatg
    21421 aagagaagat aattataaga attatcacta acattgacaa attttataga atttgatatt
    21481 ctaaaagttg tagaagaact attaaaatag cctttcgtgt agacgagagg ctttattgtt
    21541 ataggaggga tttttatgaa ttttcaagag atgatactgg cgttgcaaaa atactggtca
    21601 aagcaaggtt gtatcatgat gcaaccttat gatattgaaa aaggtgcggg aactatgaat
    21661 cctaatactt ttttaagatc attaggacct gagccttggc aagtatgcta tgtagagcct
    21721 tcaagaagac cagcagatgg aagatatggt gaaaacccaa acagactata tcaacatcat
    21781 caattccaag ttatactaaa accttctcca gataatatac aagaattata tttggaaagt
    21841 ttgaaagaga ttggaattga cccaagtgag catgacataa gatttgttga agataactgg
    21901 gaagctgcta cagttggtgc ttggggactt ggatgggaag tttggctaga tggtatggaa
    21961 ataactcaat ttacgtattt tcaacaagta ggtaatattg aatgtgagct tgagacagga
    22021 gaaattacat atggattaga aagattagct atgtacattc aagaagttga tagtgtttat
    22081 gatttaaaat ggaatgataa aataacttat ggtgaagtat ttaataaagc tgagtatgaa
    22141 aactcaatgt acgcatttga attatgtgat gcagatatgt tgtttaatct gtttgatata
    22201 tatgaaaaag aagcattaag acttatggaa aatggccttg taataccgtc atatgactat
    22261 gtgttaaaat gctctcatgc atttaataca ttggatgcaa gaggtgcaat aggagttagt
    22321 caaagagctt catttatagg tagagttaga aatatggcaa agactgttgc agaaactttt
    22381 gtaaaacaaa gagaagaaat gggattccct cttttaaagg acggtgacaa ataatgaaaa
    22441 attatctttt atttgaaatc ggtgttgaag aaatgccatc aagatttgta ggcagtacac
    22501 tagaacaatt aaaaaacaat cttagtaaat tatttgatga aaatagaata gcttttgata
    22561 aaataaatgc ttatgggaca ccaagaagac ttactttagt agtcgaagga ttgagtgata
    22621 gacaaagtga tttagaagag gaaataaagg gtcctgctaa aaaaattgct gttgatgcag
    22681 aaaataattt aacaaaacca gcattaggat ttataaaaag caaaggatta agcgaatctg
    22741 acatatattt taaacaagtt ggaaaagaag aatatatatt tgcgactata aagcaagatg
    22801 gaaaagaaac ttcagaagta ctaaaagaca tattaccaga gactataaaa tctgtagtat
    22861 tcccaaaagc tatgcgttgg ggaggaaaaa atcttaaatt tgcaagacct ataagatgga
    22921 tagttgcatt gttaaatgat aaagtattag agtttgattt agaaggaata atatcttcta
    22981 atgtaacaaa aggtcataga tttttaggtg aaagtacaat agaagttgat tctatagaag
    23041 attattttga aaaattagaa aaaaattata tagttttaga ccaaaacaag agaaaagaaa
    23101 tgataagaaa acaatgtata gaagtagcaa attctttagg tggagaagtt gaatttgatg
    23161 aagatttact tgaagaggta acttatttag ttgaatatcc aactgctttt tatggagaat
    23221 ttgatgtgga ttatataaaa ctaccaaaag aagttgttat aactcctatg aaacaacatc
    23281 aaagatattt tccagtactt aaagaaggaa aactgttacc taactttata gctgttagaa
    23341 atggtgattc ttacagaata gacaatgtta aagctggaaa tgaaaaagtt ttagaagcaa
    23401 gacttgcaga tgctttattt ttctatagag aagatactaa gagaaactta gaaagctaca
    23461 tagaaaaatt aaaaactgtt gtattccaag taaaattagg aactatttac gacaaaactt
    23521 taagacttga aaaattaagt gctgatatac ttgatagttt aggtttagta gatgaaaagg
    23581 cagatactat aagggctgct aaattatcta aggcagattt agttactgga atggtaggag
    23641 aatttgatga attacaaggt tttatgggaa aagaatacgc aaaagttgga ggagaaaatg
    23701 atgttgtaag tgaagctatt tttgaacatt atcttccaag atttgcagga gatatacttc
    23761 ctaagactaa tgcaggggtt gccttatcaa tagctgataa gttggattca atagcaggtt
    23821 tctttgctat aggaatacaa ccaacaggtt ctcaagaccc atatgcttta agaagacaag
    23881 ctttaggtat acttagtata cttatggaca gaaaagttgc tgtggatata aaaatactta
    23941 ttgaacatgc tttagacaat tattctgaat tagattttaa taaagaagaa gttgttgagc
    24001 aaataatgaa tttcttcaat gagagagtaa aaaatctatt taaagattta ggaataagat
    24061 atgatgttgt tgatgctgtt ttaagttctg atataaatga tgtttctgat atgcatatga
    24121 gagctttaga gcttaataat tggctagaaa aagatgaatt agtggagatg cttactgcat
    24181 ttaatagagt ttctactcta gctcaaaaag cagaaagtga taaaattgat gaatctttat
    24241 taaaagaaga tgctgaaatt aaactttaca atgaatttaa acaagtaaag gtaaaagtta
    24301 atgaattatt aaaggataag aaatatggta ttgctttaga tgaatttgca tctttaagac
    24361 cagtagttga taatttattt gatacagtta tggtcatgga taatgatgaa gctattaaga
    24421 acaatagact tgctttactt aaacaagtat atgatactat gctaggaatt tgtgatttat
    24481 ctaaaattgt ttataaataa aatttaaact atttataaga aataaggctg tctcaaaata
    24541 gagatagtct tatttttcat tgttgagatg atgaaaatat atttgatttc atagaaaaag
    24601 agtgtctcat aaactaaaaa gttcattttg agacacccat gttttttgta agtaaatata
    24661 ataaattata ttttatactt atcagttatt ttgtttaaaa tattatcatt tgaatttacc
    24721 cattcataaa aattgcctga agatgcgtcc gatattttat aaagcatttc aggaatatca
    24781 ctagctttaa aatctccaag tgattttccc aatctagtct tacctatttc aaaactgcct
    24841 ccaacaaata attcaaatgc atctgtagat ataccatcaa cattcttctt tttaccacat
    24901 aaacctatgc taccaacttg atgaacacca catgaattta aacatcctga tatatataac
    24961 ttaggtgctt tatttaaaat ttcttcatta ttttgtaatc taaaataatc tatgatttca
    25021 tgtaacattt tctgactatt ttgtatgccc atttgacaaa ttggaacacc tatgcaagat
    25081 atactttgtt ctaattgaga attacaacta atagttttac ttatttctaa tattcttttt
    25141 gcttcatttc catttaaatt taaaatatat aatccctctg tcattcctag tctaatcata
    25201 ggattttcaa cattatctaa ttctttaagt aaagtactta aatcctttgt taacaaaata
    25261 cctccaactg gatgtatata tacagtgtat aaaccatcct gtttttgagg tattagtcta
    25321 gaatcttgta tatctatttt aactccaggt ttagagtaat ctatttcttc aatattgagt
    25381 tcaagactac cattttcttt ttctaattta tagtattctt taaatttttc taagaatagt
    25441 tcttcaccaa gtgattcgac catatatcta accctagctc tgtttttatt ttcataattt
    25501 ccataatcca taaagaattt aatcatacct tcaacacaat ataaggcgtc tttcggcttt
    25561 ataagttcat caagttctaa agcaactttg ggttgtttac ctagacctcc acctaagaaa
    25621 actctgaaat atggttcatc atttttcaaa gtagcaacaa atcctaagtc ttgtatacta
    25681 caatgagcag tatctgtgta acaattagaa taagaaactt ttaattttct aggtaaatgg
    25741 tatgtagtag catttttgat aaaatattta tcagtagcaa ctgcatatgg agtaacatca
    25801 aagacttcac tagggtcaac tccagataat ggagataatc cgacatttct aggataatta
    25861 ccaccaccac ctctagtgaa tatatcattt tttattcctt cttccatgat atcaacaatt
    25921 gaatttatag ataaatcgtg taattgtata gcttgtctag ttgttaagtg tatcttatct
    25981 aagttgtgtt taatagctat ttcatagatt ttattaagtt gatactgaga taaaactcca
    26041 gcagatactc taagtcttat cataaaagat tttttgtctc tttgagcata aacaccatat
    26101 ccaccagaaa atcccttata ttgcatttta tttatttctc catttaaaaa ttttgaagaa
    26161 tattctttaa aattaggtag ttcatttaac aatatctttt taaaattatc cattatttca
    26221 cctcattgtt agtcttgtat aaaaatatat ctattgtata atagatatat atattattat
    26281 ctagtcagga taaaaatata acagaataat tctattaaaa gtaagaataa taaggacata
    26341 gtgagtattt tgtttttatt ttacaaatta agtataatat ttttgtttta taaaatataa
    26401 ttaagataaa tagataattt tgtaatttta atatataata tttagtagag tgtgggagta
    26461 gcacttaata tttgcaggag gagtttttgt atatgggaga aataataaat gcattagata
    26521 gagccctaga cataattttg ctgttatatc atgaaaagag agaaatggga ataactgaaa
    26581 taagtaaggc tatgggagta tataaaagta ctgtacatag aactttggtt actcttgaaa
    26641 acaaaggttt tgttatacaa aatgcagaga atggtaagta ttggctagga ataaatttat
    26701 atgcaatagg tatggttgtg ggagaaaaaa tgtcattgac tgaaatagta aaaccatata
    26761 cgaaaaaatt aaatcaagaa tttaacgaag tagttaatgt atctatatta gaagaaagag
    26821 ctcaagattc tccaagaagt atcataatac ataaagagta tggttcaaat caattacttt
    26881 cagtaaatcc atccgttggt tcaagtagtg aatgttattg ttcagcagtt ggtaaatgtc
    26941 ttatggcatt taatgattct atagattttg aaaaatatag aaaaacacca atacacaagt
    27001 atacagaaca tacaattgat aattgggatg atatgatgct ttttttagca aaaataaaag
    27061 aacaaggata tgctatagat gatgaagaac tagaacatgg actaacttgt attggagcac
    27121 ctatcttaga taaaaataat aaagctattg cagccataag tttgtcaggt ccaactataa
    27181 gaatgagaga aggggacttt gagtataaga ttaaaagagt tatagaaact gcaaaaagta
    27241 tatctgaact ttttagatga tttttaatct cgataataaa aataggctat atttaaattg
    27301 ttatttgtaa atatcagttt aaatgtagcc tatttttctt taatctaaaa ttaaatattc
    27361 ttaaaattta aaatgttatt gaaatatata agcgaatgtg ttatctttta attaagcaat
    27421 aaaaatagaa caaggttcta tactatagaa caaaattgat gcatatatag tatttataca
    27481 aaatataaat attatatatt taaaattaag taaaaatatt acataaaggg gagatttgag
    27541 aaatggaaaa agtcaagttg agtgttgaaa gatgtaaggg atgctatctt tgtattgaag
    27601 cttgcaaaaa agatgcaata agtctttctg actacacaaa taaaaaaggc tttgtaacta
    27661 ttaaagtcga tgaagaaaaa tgtattcaat gtggcgcttg ttatacaatg tgccctgatt
    27721 tagtatttga gatattataa attattttta ttagagggga gaaaaggtat gcaaagttta
    27781 ttaattaaag gaaatgaagc tttagcagaa ggtgctatac gtggtggttg cagattttat
    27841 gcaggttatc caataacgcc acaatcagaa atattagaaa tgatggcatg gagacaaaaa
    27901 gaagttggag gagtatttat ccaaggtgaa tcagaaatag ccagtgtaaa tatggttatg
    27961 ggagcaagtg cacttggagc aagagctatg acttcttcat ctggtccagg attttcatta
    28021 aaacaagaag gtattgcata ttgggtatca gctggtttgc cagcagttgt agcatgtgtg
    28081 caaagatatg gtataggtga tggatttata ggagctggtc aagataatta ttggcaagca
    28141 gtaaaaggcg gtggaaatgg agattatcat ttaatcgtgt tagcacctaa tagtgttcaa
    28201 gaaaatatgg atatggcata tgaatctttt gaattggctg aaaaatatat gcatccagta
    28261 cttatacttt ctgatgctac aataggtcaa atggtagaac cttgtatagc accaccaatg
    28321 aaagaatacg atatggataa agctccatgg gctgcaaaag gaacacctgt aggagaaaaa
    28381 aataaagtaa taactgatat aacatatttt gaagaccaag atacatggca aaaagggtat
    28441 atagaaaaaa tgagaaaagt tcaagaagat gaacaaagat gggaagagat agaaatagaa
    28501 gatgctgaag tggtatttgt ggcatacggt atttcatcaa gaatagcaga aggtgcagtt
    28561 agagatgcta gagcaaaagg aatgaaatta ggtctaataa gaccaaaaac attgtggcct
    28621 tacccaagaa aagcatttaa gaaattaagt gattcattga agggacttgt aacagttgaa
    28681 atgaacatga tggcacagat gaaggaagat gtaattatag catgtgataa tagatttcca
    28741 gtatattcag tagcaacagc tcaatatatg gcagaagtaa atcaattaat agattttgct
    28801 caacagatta tagatggaaa agctaagcaa gaggaggtat tttaattatg gctaaaaaag
    28861 caccagcaat aatgatgtgt gaaaatatgt tctgtggagg ctgtggacac tctatagtcg
    28921 atagaattat tggagaagta ttaacagaaa tggatatatg tcaagataca attatatgtt
    28981 cagatatagg ttgtaatcat atgtttcaat ttagtatgaa tgtagatgtt gtcgttccac
    29041 ctcatggtaa aatgggagca gcaatggcag ctatgaaaag agttagacca gataaatata
    29101 tatttacaat agctggagat ggtggagctt atgcaatagg gcttggagaa actatgtcag
    29161 ctgctactag aaatgataat gtaatatttc ttgttatgaa caataatatg tttgcaatga
    29221 caggagggca aatggctcca actactatag aaggtcaata tacagcttct actccagcgg
    29281 gtagaaatta cgcagatcat ggttcaacat ttgatgttgt aaaagttatg ggaaatttag
    29341 atatagcata tctagcaaga ggaacaataa ctaaccctaa agaaataaat acaacaaaaa
    29401 gatacatcaa aaaagctcta gaaaaacaaa aagaaaagaa aggtttttgc ttaatagaag
    29461 tgcttgtacc atgtccaaca aactggggat taaagccagt agatgctatg aagagaattg
    29521 aaaatgaact tgttccaaag tatccacttg gagaatttat tgattaggga ggaaataata
    29581 tgttgaatga aattatatgt gctggttttg gaggacaggg agttcttaca gcaggaaaaa
    29641 ttataatgta tgttgcatat aaggcagaaa agaaaattac atggttccca tcttatggaa
    29701 atgagatgag gggaggaagt gcaaattgca atgttgttgt aagtgatgaa aaaattgcaa
    29761 atccttgtgt aaaaaatcca gatatactat tgggaatgaa cagcgtatca gtagataagt
    29821 atgaaagttt aatgaaaaaa aatggttata tgtttgtcaa tgaatcacta gtaagtaagg
    29881 atagaaagta cagagaagac attaatgtta taaaagtacc tgttactgaa atagcacaaa
    29941 atttaggcaa tgaaaaagct gctaacattt gcatgttagg tgctatggta aagagtttgg
    30001 atttatttac aaaagaagaa tttgaaagtg gtatgtgtga atactttgaa aatcaaggca
    30061 aaggtaaatt caattctaaa aatgtagaag catttgaagc tggatacgac tacgaatgaa
    30121 tattttaaat atttaaaata attattgaaa tacttatttt tatatgttag tatttaatta
    30181 ataaaatata gaacgtcgtt ctgaacaata ggacgaagtc tttaggtcgg aatacaagaa
    30241 cgacgttctg tatagtagaa ctagggggtg ttaaattgaa agttttagta ataaatcctg
    30301 gtggtacatc cacaaaaatt tctgttttcc aagatgaaaa tgaaattttg aaaaaaaata
    30361 taacccatac aagagaagat ttaaaaaatt tttctaaagt atttgatgaa tatgattata
    30421 gaaaacaact gatagtagat attttaagta gtgagaatca tagtataaat tcttttgacg
    30481 cagtagttgg tcgtggtgga cttatgaagg ctataaaagg tggtacctat actgtgagtg
    30541 aagaaatgat tgaggatatg agaaatgaaa taaatgggga acatgcatca aatttaggtg
    30601 cattattagc taaaactata gctgatgaaa taggagtaca atcatttgta gtagacccag
    30661 tttctgtaga tgaatttgat gatgtatcga ggattacagg aatatcagac atagaaaaag
    30721 caagttggtt acatgcatta aaccataaag ctgtttcaag aaaaattgca caaaaactag
    30781 ggggaaaata cgaggattat aactttattg tagctcattt aggttcagga atatcgattg
    30841 tagcacataa acaaggcaaa atgattgatg gaagtggtgg taggtctgat ggtccatttt
    30901 ctccagaaag gagtggtgga ttacttgcat atcctcttat agaattgtgt tactccggaa
    30961 aatatactca tgatgaaatg gtcgcaaaag taagttcgat tgggggaatg tacgattatt
    31021 taggaacaaa ggatatgata gaaattgaaa acagaatcaa ggagggtgat gaaaaggcaa
    31081 aacttataat ggatgcattt atttatcaag tagcaaaaga aatttctatg tatggagctt
    31141 cactttcagg gaatgtagat agagttatct tgacaggagg gatatctcac tcagaaatgg
    31201 tagtcaaagg agtagcagaa aaagtttcat atctagctcc aatagagata gtaccaggag
    31261 agatggaaat ggaggcactt gctctagggg cacttagagt acttaatgga gaagaaatag
    31321 caaaaactta ttaatattta ggagaaagag tatgttaaaa gattttaata atttattaga
    31381 agaggctaaa aagcttgaac ctgttattgt aagtgttgct gttgcagaag acaaagaagt
    31441 attaaaggct gtgaaatcag caacagattt aaacattata aagccaattc ttgtaggaga
    31501 caaggataaa atagaaagta tatcaagaga aattggatta aaaggtcatg aaataatagg
    31561 ttgtcaaaat cccgatgaat cagttaaaaa agctgtagag atagttaaaa ataaggaagc
    31621 taaagttctt atgaagggat tagtaaatac aagtgtctat atgagagcta tattaaataa
    31681 agaaacgggt cttagaacag gaagattatt aagtttgctt gcagtatatg aattacctca
    31741 atatcataaa cttctttatt gtactgatag tggaataaat gtatcgccaa acttaaatca
    31801 aaaaaaagat ataatgacaa atgcacttct tactatgaaa agtataggca tggaaaatcc
    31861 taaaactgcg atacttactg caaatgaaat ggtagaccct aagatacaat ctacagtgga
    31921 tgccaaccta cttgtagaga tggaaaaatc gggagaaata ccaaagtgta tagtggaagg
    31981 tccaatagca tttgatgtag catttgatgc acatgcagca gaacataaag gtattaaaag
    32041 taatattgct ggtgatgttg atttattagt atttccaaat atagaagcag ggaatatatt
    32101 aggaaagtca tggcttagat ttaataaagc taagtgggca ggtatagttt taggagcaac
    32161 aaatccgata attttaggtt cacgttctga cacagctgaa ataaaaataa attcaatagc
    32221 attagcgtgc ctagcatcac aataagaaat tattattaag gaggaaaaag tattatgaaa
    32281 tatgcaaaaa gaatggatat ggtaaaagct tcagctataa gagattctca aaagaaaata
    32341 gctcagaagg tagcaagtgg tggaactgtt atatcttttg ctgcagggct tcctgaccca
    32401 aatttatttc caatagaaga gataagtgaa ataactcaaa aagtacttaa tgaaagggga
    32461 aaatttgccc tagcatatgg acctactaaa ggtgaagatg agttgttaga tctattagta
    32521 aaaagaatga aagaagaaga aaatattgat acaaaagcag aaaatattat aataactact
    32581 gggtcacaac aagggatagc attaagtgct atgattttat tagaaaaggg agatgtagta
    32641 gttacagaaa atccaagtta cttaggtgca ataaatgcat ttagacctta tgaatgtgat
    32701 tttttaggag tagatacaga tgaagaagga atggtaacag atgatttaga caaattatta
    32761 tctgaaaatt ctaacataaa ggtgatatat gtaataccaa catttcaaaa ccctacagga
    32821 aaaacatggt ctttacaaag aagaaaagat tttatggaag tcgtgaataa atatgatgtc
    32881 atagtaatag aggataatcc ttatggagaa ataagattta caccagaacc tctacctaca
    32941 cttaaatctc ttgatactaa agataaagta ttgtaccttg ggtcattttc aaaggtatta
    33001 tgtccaggat ttagagttgc ttggatgtgt ggtaatgtag acatcataga taaggcagaa
    33061 cttttaaaac aaggtataga tttacagtca aatcaatttt cgcaagtaca agtaatagaa
    33121 tttttaaaga aatacaactt aaatgaacat atagaaaaaa taagagcaga gtataagaaa
    33181 agatgtctgc taatgttaga tgctatgaag aaacatttcc cagaggaagc taaatataca
    33241 gaaccagatg gaggaatgtt tatatgggtt gaacttcctg aaagtataaa tgtagatgat
    33301 ttattagata aagccattga tgctggagtt gcttatgttt ctggagagtc cttctttgca
    33361 aataatggtc caaaaaatac tatgagactt aactatacaa caatgtcaga agaacaaatc
    33421 gttaaaggtg ttgagatact tgcagaagtt ataaaaaaag aactcaatta tgcttgtgaa
    33481 taaatataaa aagtgagggt ttaaatatgg gagaaaaaga aaacggtata aagtttggaa
    33541 agttaatgtt tcaacttgtt attatagcaa tatcttggga attagtttat attataccat
    33601 ttatccaata tacattatat gatccaattc taaaagcatt agaatgtaca aacactcaac
    33661 taggttttct acttacaatt tatgggttag gtaatatatt tggagctcct ataggaggct
    33721 ggttagcaga tagatttgat tatagaaaga taattttagg ttctgtattt cttaatggag
    33781 tagtatcatt tttatttgca tttaatatga actatccatt tgcagttgct acttgggtag
    33841 gttgtgcaat cacatcatta gttatgaact atccttctat ggtaaaaata cttagagtta
    33901 taggaaaaga taatcaaggt aaggtttatg gatttaatga agctatggtt ggagtttctg
    33961 gagtagtaat gggagcaata ttcttatata tttatacatg ctttgcaact cctacattgg
    34021 gtatgagatg ggtaatgata tctttaggaa tattatcaat agcaatgtgt ccagtattat
    34081 ggtttgtaat taaagatgta gatattaaag aagaaagaga agaagcaggt gaaaaaatgt
    34141 ctgctggtga ttttataaca gtactaaaat caccaaatac ttggctagta ggaataagta
    34201 tattctgtgt atattcattc acagttacaa tgtcttattt tacaccatat ataacatctg
    34261 tacttggagg ttctgtagca ttatctggtg cattagcaat aataagacag catggtctaa
    34321 aattatttgg agcaccattt ggaggatatt gtgcagacaa attaaaatct cctacaaaag
    34381 tacttttacc aatatatgta tttggtatag cagtaatagt tttattccta gtattacctg
    34441 catcaactcc aatgactata ttcatagctt taacatttgt agtaggtata ttaggttaca
    34501 tgggaaaagg tatatattat gcagtacaag atgaagtaaa agttccagtt aaatattcag
    34561 caactactat aggtatagct gcagctttag gattttcacc agatgtattc caatttgcat
    34621 taataggaca ctggatagat acttatggca ataaaggtta cacatataca tttatattcc
    34681 aaatagcaat tctagttatt ggaatactat cttgtttata tatattaaag gttaaaaaga
    34741 gaagagcaag taaattagaa gcttaaatat tcaatttggt aattaagtat atataaatac
    34801 aatacttatt ttgatgaatg tgattgtata aataacataa aaaatatcaa tagattaagt
    34861 tttataataa tgtttagaga ataaagtata aaaatcaaaa tgttatcaag ttttctaggt
    34921 tttaacataa agttacccct gaaggtgtaa aattgagtgg caattattat ctattttctt
    34981 acctacataa acctatttaa tttaaattct aagagatttt aaaaatagat ggtagttgta
    35041 ctcaatttta aacctcataa taaatacgaa aatttaaaat ctaactagat actatttaat
    35101 tatatattaa taaatatata ttgtactatt tatataataa taatttcagg cttttcatta
    35161 tatgtattcc aatttatatt gtttgattat tattcaaaca cacgtcgtta aaaattttat
    35221 aaatttatgt ttagatatga ttaatactct tgattttaga aataaatatt tgtagattgt
    35281 agattaaaga taatataaat aaatagaagg tagatttttt agatatatta atataaagat
    35341 tatataaaat attgaaatat agctgtttaa attattgtct ataaatataa aatgaatggt
    35401 ggtgagttaa gtgaccgatt tagttaacac cattaatgga attgtttggt cacccgtatt
    35461 agttgcaatg tgtttgtgta taggattata tttttcattg aaattaaaat tttttcaaat
    35521 aagagatgta aaagaaatgt ttactctctt gcttgaagga gatagttctc atgttggtat
    35581 atcatcattt caaggttttg ctacatctat ggctggaaga atagggactg gaaatatagc
    35641 tggtgtagct gtagcaatag caatgggagg tccaggagca ttagtatgga tgtgtataat
    35701 ggctacatta ggttcagcaa ctgcatttgt agaatctact ctagctcaaa tatataaaga
    35761 tgagcatgat gggcagtata gaggaggacc tccatattat tttgaaaaag gtcttgggtg
    35821 gaaaaagtgt tcagttttat tttcaatagt tgcaataata agttatacat tttttatgcc
    35881 tggtacacaa tcaaacactt tatatctagc aatgaatcaa gcatttggat tttcaaaaat
    35941 gacaatagca gtagcatctt ctattgcatt agcgataata atttttggag gaattaaaag
    36001 gattggttta tttgctgaaa aagtagtacc tataatgggt ggagcatacc ttattatgac
    36061 attagtaata attataacaa atattagttt agttccagag gctattgtaa caatgtttaa
    36121 atctgcattt ggatttggtt cagtttttgg aggaatgcta ggttcagcaa tatcttgggg
    36181 agtaaaaaga ggtatatact caaatgaagc aggagaaggt tctgggactt atggtgcggc
    36241 agcagcagaa gtgagtcatc cagccaaaca aggattagtt caagcatttt ctgtttatgt
    36301 agacacatta ttaatatgta tggctacagg tattatgatt gtaataacag gaatgtataa
    36361 tgttacaggt gtttgcacag cactgccagg tgtagaaccg ggaccacaat atgtacagag
    36421 tgcaataaat acattacatc cacaattagg tgatattttt atagcaatag ttttattatt
    36481 atttacattt acaactttat tagccttctc atatatgatg gagactaatg tatcttactt
    36541 agtaactaga attaaagcag aaaaacatga aaagtacata attaatgtct gtagatttat
    36601 gcttatagca tgtgcagcaa tgtgttgttt tatagaacca cttacaagct gggcattagg
    36661 tgatatatgt ataggtgtat taacatatat aaatttaatt gccatcttta cactaaaaaa
    36721 accagctata aaggcatatt atgattatat aagacagaag aagatgggaa taaaaaggag
    36781 tgatagaact tttaacccta tagagttaga tataagaaat gctgagtttt gggaaaatag
    36841 atacttaaaa gaggataagc atgagttaaa ttaaagttat aataaaatat aaaaattact
    36901 aaataaattt agtgggaggt aagattggta tgaaagaaag aataatacaa gtggctgatt
    36961 caaagaaaga aaaaattcta gggctatgtc aatctttata tgatgaacca gaaattgctt
    37021 tgcaagaata taaatctgct aaaaaaatat cagaattttt aagagaagag ggttttgatg
    37081 ttgaggaaaa cttggcaggt atggctacag cttttaaagc aaccaagaaa aatggagatg
    37141 gtcctaaaat agcatttata gcagaatatg atgctcttcc aggcaatgga catgcatgtg
    37201 gacatcattt aattgcatct atgggagttg gagctggaat agctctttca agtatactgg
    37261 atacttacaa gggagaagta agtataattg gaacacctgc tgaagaaact ggagatggaa
    37321 agccttactt gatagaacat ggtgtatttg atggctatga tgcagcaatg atgatacatc
    37381 caaattcaaa aacttgtgta acacctgaaa ttatagcaat aggaggtcta gatttcatat
    37441 ttactggaaa agcatctcat gcaggagcta agccatataa cggaataaat gctttagatg
    37501 cagtagtatt actatataat aatataaatg cactaagaca acaattagta gatggaacga
    37561 gaatacatgg tattatacta gaagcaggaa ctgctgcaaa tgtaatacct gatatgggaa
    37621 aagtaagatt agagataagg gcaaaagaac aaaattactt tgatgaagta gtagaaaaag
    37681 tgaaaaattg tgctagaggt gctgcaatag ccactggatg tgaacttgaa ttttatcact
    37741 ttgaaccaac ttgccaagga ttaaatgaaa ataaagtttt ggtagacata tttacaaaga
    37801 ttatggagga atttggaata tatgaagatg aacaagtaat gttaggttca acagatatgg
    37861 gaaatttaag tcaaataatg ccatgtatac atcctttgat gaagttttct gaaaatggag
    37921 aagaactaca tacaaaagaa tttttggagg cttctataaa ttcatatgca aaagatagag
    37981 taattgatgg tataaaaata ttagctttaa caggatttaa tttatttgaa aatccagagt
    38041 tattgaaaaa aatgaaggaa gagtagaact tagactattt ttaattatac tctttaaaat
    38101 aagaagagtg tctcaaaatg aactttttag tttatgagac actctttttt gtatgaaatt
    38161 aaatatattt ttattatttt aacaatgaaa aagaggctta tctgttttta tatgaccttt
    38221 tttaacttgt agcacaaaat atcatgaatg attacaattc gaatgataaa atcgattata
    38281 agatatatag gaggggtaca tatggaaact ttagaagtaa gaaatattga attgagtggt
    38341 acaaattatg agataggata cagactagga gaattggttg ctaatatgcc agagataata
    38401 gaaggtcaga ttaataaatc taatctggta agcaaaaaag aagaaaaaga gatgatagag
    38461 ttgtttgata aatattgtcc aggtcttaat gaagaattgc aaggttttgc tgatgcaatt
    38521 caagtgaatt gtaatcaaat tttatattat actatgactt atcttaaacc aggttgtagt
    38581 caagttgcat tagcaccaga attaactgaa aatgggcatg tactatttgc acgtaatttc
    38641 gatttctcac acaatatgga ggattttgtt ttatgtaaaa ctaaggtaaa tggaaaatat
    38701 gcacatatag gtactaccgt tatgcaattt ggaagaggtg aaggtatgaa tgaatgtggc
    38761 ttaggtgtaa gtcagtcatc atgtggtatt cctgtaggca attcagatgg tttaagaaaa
    38821 ccagcaattg taggtttaca gttttgggct gttattagat atttgttaga aaattgcaaa
    38881 gatgtagatg aagcattaga atatttaaaa gatatgccaa ttgcatacaa tattaattta
    38941 ttgcttgcag ataagtctgg aaacattgca cttgtggaga ctttagatgg gaaaaaagaa
    39001 gtaaatataa tcaatagttt agaaagtaaa agagaatatt ttttacactc tactaatcat
    39061 acacatattg ataaacttca taaattagag ccacaatcaa tgaaaaattc tattcataga
    39121 tataaattaa ttaaagaata tataaataag tctaaaaaaa ttggagagaa agagttaatg
    39181 aatttattgt cttcaaaata tccaaatggc ttatcttgta attactataa tgattttttt
    39241 ggaactttaa aaagtatagt tatggattta aatataggaa agtttaatat tttatggggt
    39301 ggactagaga ataaatggga gagctactat ttaaaaaatg acattaaatc tataacacag
    39361 aggataaaca taaatattga aaaagcacca tctgactttt ttgatttcat tgaataaaaa
    39421 atgtatttaa ttattctaaa taattaggat atataaatca actaaaagtt tttatttatc
    39481 gtattgaatt agttataata ttttagtata gtaaaaaata gtgctatttt acatatttaa
    39541 agagtttaag tagaagagag gtgccatatt ggattactta aagtatttta aaaaagctgt
    39601 aatgtatatt gagaataatt tacatgaaaa tataactgta aatgatgtgg caaaagaaac
    39661 tggatattct tattatcatt taacacgctt atttaagtct atgtttggtg agagtgtagg
    39721 aagttatata aaaaaaagac gattagtaag tagtacaaaa gaacttttat atagtgataa
    39781 aaaagtgata gatatagcta ttggtagtgg atttgaatct tcggaagcat ttagcagagc
    39841 atttaaatct atatacaagg ttagccctat agaatataga aaaaatagaa ttgatgtatt
    39901 tgttggtaaa aagaaaaaat tagagttaga ttttatgaga catcttgttg gaaatataac
    39961 gattaaacca gttataaaag aaatagaaaa aataaaggta ataggtataa aggataaagt
    40021 aattttagaa aataattcat tacctgactt gtgggagaaa ttcagaaaag tacatcatat
    40081 tgtcccaaat actttgccat caaagagagt ttttggaatc tgtgaagcaa tctctgaaat
    40141 acacctagtt agtgaaagta tggaatttaa tgagataata ggacttgaag ttaatagtta
    40201 tgatgtgatt ccaaattcat ttgtttcaaa aactattaag gaaggaaagt atgctatatt
    40261 tactcatact ggtagcttag ataatttaga caaaacttat gaatatatat ggggtacttg
    40321 gtttttaagt tcaaaagaag aacttgatat aagagatgat tttgaagtat atgatgaacg
    40381 atttttaggt cctagtaatg tgaactcaca aattgatatt tatataccta taaaataatc
    40441 tataagaaaa ctaaaaaata atttgattaa gaaatagatg ttcgtaaaag agcatctatt
    40501 ttttattttt atcagattta gataatttta ataataaaag aaataaaaat aagttcttaa
    40561 atttct
//
LOCUS       DAMJVG010000031        40366 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.031, whole genome shotgun sequence.
ACCESSION   DAMJVG010000031 DAMJVG010000000
VERSION     DAMJVG010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 40366)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40366)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40366
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.031"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(260..1099)
                     /locus_tag="PC512_001749"
     CDS             complement(260..1099)
                     /locus_tag="PC512_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDF2441495.1"
                     /translation="MSDIKNEVSKKTLSKKDVIKSWLRWFFFAQSNYNYERLQSTAFS
                     HSMLPVLKKLYPDKEELKQEVETHLAFFNTEPICGCVIHGITIAMEEEKANGADEISG
                     DGMNAIKTGLMGPLAGIGDTLTQGVITPIVLAVCIGLTEGGASIAGPILFVIAQYIIM
                     TSISFGMWTNGYKYGKKAVESILQGGIVNKVIEGASILGTLVMGGLVGRFINLSTPIS
                     YTSGDFKFSLQTDLLDKIFPGLIPLVLTLLVLFALKKGLSPIKIMFILIVVGAITGIL
                     GLF"
     gene            complement(1123..1881)
                     /locus_tag="PC512_001750"
     CDS             complement(1123..1881)
                     /locus_tag="PC512_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2441496.1"
                     /translation="MHISLIQAVLIAIFYYLSWSPWLTYVGFFTWNRPLLAGFVTGII
                     LGDPVQGAIIGAGINMIYLGFISAGGAQMGDPAFAGYVGTALAIASKLDVSTAMAIAV
                     PLGTVATVLWIGKMTVNSFFAHWADREVQKGNVDRVAFINIVPPQILLFAMSFIPALL
                     VVYFGPNAIDGMLEVMNDNVLHVFNVIGAMLPALGIAMNLKLIGNKFTMPFFILGILM
                     AVYFKVDIIVISVIGVILALTITSIKYGKDSATS"
     gene            complement(1928..2401)
                     /locus_tag="PC512_001751"
     CDS             complement(1928..2401)
                     /locus_tag="PC512_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2441497.1"
                     /translation="MSNIALTRIDDRLIHGQVITAWCKITSAKRIVIVDDLVVKDPFI
                     VQVLQMAAPSTVKVEVHDVESGAEVLKSYNGDENLIVLVKYPKTVLGLVNSGVDLKEL
                     NVGGMGAGLGRKSFYKNISVSDEEKEIFRELISKDVKCFIQIVPDAKKIDVGTLL"
     gene            complement(2430..2846)
                     /locus_tag="PC512_001752"
     CDS             complement(2430..2846)
                     /locus_tag="PC512_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2441498.1"
                     /translation="MIHMAGIIIATHGNMAKAMLESAELIVGKQENVETLGLNHGDSI
                     DEFSRKLEDGIEKYKDEGVLVLLDFYGGTPFNTSAIIINKFAKVCELECLTGVNLPML
                     LELFLNRDTMKLKDLKNLCEEVGISGIKDVKTVLKL"
     gene            complement(2893..3945)
                     /locus_tag="PC512_001753"
     CDS             complement(2893..3945)
                     /locus_tag="PC512_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HDF2441499.1"
                     /translation="MKSVRFYGIRDTRVEDVDVPKILEKDDVIIKVKVAGICGSDISK
                     YSKTGPHMVGEILGHEFSGEVAQVGKEVRSFKIGDRVAVCPAMPCFECDECKKGLYSR
                     CNNVAIIGNKELGGCFAEYTKVKERNLIKIPDEISYETAAALEPVCIAGHGLFRSEAK
                     VGDTVVVLGTGPIGLFSIQWAKIFGSTKIIAVDVFDEKLDLAKELGADICINAKEKNI
                     VEEIKRLTDGDGADIVIESAGTPLTCGQVLLLAKKGGTVLYAGVPYGDVALTREQFEK
                     IVRSELTVKGTWFGNSFPFPGKEWSAGLYHMQKGDMNVEKLVTHRINLEEVPAYFEKV
                     YKRDIFFGKIMINIDN"
     gene            4341..5021
                     /locus_tag="PC512_001754"
     CDS             4341..5021
                     /locus_tag="PC512_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HDF2441500.1"
                     /translation="MKKVYQGKTKDVFELDNGNYLLKFKDDVTGKDGVFDPGENSVGL
                     SIDGIGRANLETSVKFFEILNNAGIKTHYVSANLEEATMEVLPAKVFGNGLEVICRYR
                     AVGSFLRRYGSCVEEGAKLDCYVEATLKDDDRCDPLITSEGLEALNIMTQAQFDSMKS
                     MTQKISNIVRDTIAEKGLELYDIKFEFGFYNDEVILIDEIASGNMRVYKDGVIVDPMD
                     LTALLLDK"
     gene            complement(5154..5474)
                     /gene="sugE"
                     /locus_tag="PC512_001755"
     CDS             complement(5154..5474)
                     /gene="sugE"
                     /locus_tag="PC512_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000118520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter SugE"
                     /protein_id="HDF2441501.1"
                     /translation="MKWLFLFVAGLFEVFWAFQLKNSHGFSKLTPSILTVVGMIVSFY
                     FLSLALKHLPLGTSYAIWTGIGTVGTAIVGMAILNEPISISRIACIGFIVVGIVGLKL
                     LSTN"
     gene            5856..6683
                     /locus_tag="PC512_001756"
     CDS             5856..6683
                     /locus_tag="PC512_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HDF2441502.1"
                     /translation="MNFYKIAVCQMITTENKIENINHAVDMVTEAAINGSKIVVLPEM
                     FNCPYENKYFPKFAEEYPGETTTILSKLAEKHGIYLVSGSIPELEDGKIYNTCYVFDK
                     NGALIGKHRKMHLFDIEVTGKVSFKESDTLTAGNDVTVIDTEYGKVGIAICYDIRFPE
                     LSRLMALKGAEIVILPAAFNMTTGPAHWELSIRMRALDNQIFYVGAAPARNMNASYIA
                     FGNSRISDPWGRIIAQADEKECIIYADIDRDLIPDIRQQLPLLKHRRTDLYELNTLK"
     gene            7505..8179
                     /locus_tag="PC512_001757"
     CDS             7505..8179
                     /locus_tag="PC512_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2441503.1"
                     /translation="MNNKILVVDDEEGIITLLKDYFEMNGYEVYTAQSGKGALKKISK
                     NPDIILLDINMPEIDGIEVCNRIRDYVSCPILFLTARIENTDKINGFRAGADDYIVKP
                     FDLDELGARVSAHLRREKRKSNQTKIKFYNDLTIDYEKRLICIDNNQISLSKKEFDIV
                     ELLSMNPGQVFDKEKIYDRVWGYNSNGNSDVIMEHIRKIRIKLSKHTLENYIETVWGV
                     GYKWIK"
     gene            8167..9327
                     /locus_tag="PC512_001758"
     CDS             8167..9327
                     /locus_tag="PC512_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF2441504.1"
                     /translation="MDKINNMSLKKAFFVLTLSSLIIASTLTTFSYILLNNLYNSIQD
                     KYLKTPINTGFITIVQNNVNQFSDYDKTLLNIINILQLVLPLIFFIGLLLLADIIFYK
                     VKLKTPIEILNKGAMEISNNNLDFCLEYNNNDELGNLCNAFEKMRSELNKNNIKMWTM
                     INDRKQLNAAFSHDLRNPLTVLKGYSNYLTKYIPTGKLSDEKILSTTQLMSEHINRIE
                     YYVENMSNAQRLEDLVVSKSMSNINKFIENLDENISIIAKQEGKSFTLKSQINNINLF
                     FDENIILRVVENIISNAFRYARNNVSILIYLEQELLTFVIEDDGIGFSKESLKLALRP
                     FYRDKTLNDSNAHFGMGLYISKILCEKHGGSISIENNSTNSAKITAKFSTRN"
     gene            9598..10071
                     /locus_tag="PC512_001759"
     CDS             9598..10071
                     /locus_tag="PC512_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HDF2441505.1"
                     /translation="MLSFTFCSLPFWICYFWCGISDIFDGLIARKLRQQSGIGAKLDS
                     IADFIFSVTILVTVGKNIALPMYLWWCIVAIALLRLISYSIGFFKYRTFSSLHTLMNK
                     ITGISIFAFPLLYICFGLDVAGIMICIVAFLSSFEEIAIMIKSKELNRDIKSIFM"
     gene            10357..11025
                     /locus_tag="PC512_001760"
     CDS             10357..11025
                     /locus_tag="PC512_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2441506.1"
                     /translation="MIIKAKQLSKIYGSNNNKVIALNNVNLEINSGEFVSVIGPSGSG
                     KSTLLHILSGLDNPTSGQVLLDDKDIYKHTEKELSALRRKSFGFVFQQFNLLPVLTAS
                     ENISMPVLLDKKQPDKEYLNEISSLLGIADRLNHLPHELSGGQQQRVAIARALIAKPD
                     IIFADEPTGNLDSKSGSEVMNLLIKTSKQFGKTLVVITHDDRIAKLADRKISIIDGVL
                     MEVK"
     gene            11028..13496
                     /locus_tag="PC512_001761"
     CDS             11028..13496
                     /locus_tag="PC512_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2441507.1"
                     /translation="MKNYLSLSIKELKSQKLMTTFIIIAIVLSTIMTTVVGQSIGILQ
                     NLRIEQARSFNGDRHVSFHQLTKNQVDDIKKDDRVYQAGTSITLGSSKIKDSGISVLV
                     KEYDKTGLSNYPKLMKLKSGNLPKDKNEIALDENTLKLMGIKPRLGVTIPMNLDISLL
                     NDTIPPYNYTANFKLSGILEDDYTGYVSGIVNGIVGKGASENLLPKRYILSSLDFKIK
                     QQEKFQEIVNQLAKKINLSHNSIQYNWIYLNALKIQFEKDENSSNSDGISMIILVSLF
                     VALLVLLASGLVIYNILKISVTKKIKEYGCLRAIGAEPNQIYKIVILQILILCTIAIP
                     IGAVIGIISSKGITGMVTNILNPDILLANDNKEITELIHKNTTAYIFPLVLSTSISLI
                     FSLISALPSAIYASHVSPKIAMAGSTTKIKRKIKREKTIKNFERHLAWLNLKRNKGRT
                     IITILSLFMSITVFVALSEFSNVLDVSRSVSNLKEGDFSLTNEISGFDKSILDKIDKM
                     KNVNRTSFIKYSEYKQGEIDTDINFENSGEMLKIIGIDEQTLKDLMPSITDSILEDFK
                     NGSICFIKNPIAISTPGVKTRHTNLKPKDNITINKKQLDIYSTVDKMFFLQGNGWING
                     VDVIVYDSVYNTLTNKNKFNQINIYAKDKSKLEQIRLSIEQICENNPGSHWISYIESD
                     KQLKESFKQIEFLAWAVILFVGLIGTLNIINTTHTNINTRTNEIGVKRAIGMSNSSLY
                     KMFLWEGVYYGIFATIFGSIAGYVSAIIINMATIEKLDFTNIPITSILQATIISILAC
                     IIATLIPLRKVKKMNIIDCIDVNL"
     gene            complement(13735..15159)
                     /locus_tag="PC512_001762"
     CDS             complement(13735..15159)
                     /locus_tag="PC512_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2441508.1"
                     /translation="MKNQSLITQFRHTFIFIIIASIVATVITYVFALYLYIHSLNKDI
                     YPPNYYERQVPRIEKYINEKNITLLSQSNEEGLKRTIRGDDMLYQVVDNNGNILYGTN
                     PKKLFKTKEELFNNFINKTVRKGGYIHTVPIKGDNGKIEGAVILFYQVKITFANIRGR
                     FVFAVIIMALFSPFLYIVGFTRWLSKRFVKNINQPLHLLIDASKKIKEKDLDFEIDYY
                     SDNELGKLCSAFSEMKDELKGSLSAQWKMEQERVEMVEALAHDLKSPLSIILGYTDAL
                     IGNNTDDNEKLHRYLTVIRENTEKSAALVQKMQYTSDLEKSNIQLNLVPINLPEFLRQ
                     KVQDYELQAHQKEVELILKMQGNIQSPIQIDVDRLTRIFDNIISNSLQYTPSGGNISI
                     TVKDEKNCISYEICDSGRGFSSKDLKKALDKFYRGDEARQTKGGHSGLGLYIVKQLVE
                     QLGGSVKIENSKSGGACVKFWHSI"
     gene            complement(15178..15870)
                     /locus_tag="PC512_001763"
     CDS             complement(15178..15870)
                     /locus_tag="PC512_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2441509.1"
                     /translation="MSKILIIDDEMDLVMLLEDELKAKGHEVLIAYDGQAGIELSKQE
                     PDLIILDIMMPKMNGFEVCQAIRDDVLCPIIFLSAKQSETDKIKGLTFGGDDYVTKPF
                     GLRELMARIEANLRREKRSQYINEENKRSTLYFGKLCLYMKERAIKIDGKNIDLTKIE
                     YDIVELLALHAGQVFSREQIYEKVWGCDSEGDSSTVVERVKKIRAKFSAVTPEKEYIS
                     TVWGIGYKWNKM"
     gene            complement(15925..16701)
                     /locus_tag="PC512_001764"
     CDS             complement(15925..16701)
                     /locus_tag="PC512_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutG family
                     permease subunit"
                     /protein_id="HDF2441510.1"
                     /translation="MIKLLSSEWLRAKRTAVQWLTLFMPIIFSLCVVFYLTTKSGSTQ
                     EFAFEGFFTVWTVFIIPIGVGILAGFIVQEEELAGNFNGFLCVGISRVRLYLGKFLFL
                     LFCLTICTFIATLILCIGMSIAVPSGATIWLFLSAAGLVVIGTLPLLAIHLWVSFAWG
                     MGASIGISIGGILMAAILGLTSVGEKVWAFVPWTWPVKLGMLPGIYFIKEAGTISTEA
                     FYSKVMQTASIELIVVAIGLIIFLIGGVIWFKMWEGRKSY"
     gene            complement(16698..17468)
                     /locus_tag="PC512_001765"
     CDS             complement(16698..17468)
                     /locus_tag="PC512_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="HDF2441511.1"
                     /translation="MNALQSELLKYKRTFMGKLIVFFPVSFAAYAFIMQSTLMQNPLS
                     QTTSWAWQSLLALIFNWWSFLFLPIGFALFATLVAFQEKKAGNYRALRTHNVSPMTLW
                     INKVIAMAVYSFISTLVLIVVTIITGLILKAGPVPFGQIIGASIVCWVVSLAILPLQL
                     WLATWKGMFLSMGVGALGMIFGVLAATKPFWIAVPWSWAVRMVCPIINIHPNGTILEA
                     GDPLLNTSVIPIGIVVSLVVFIVLTALTAAWFNRRDDK"
     gene            complement(17465..18169)
                     /locus_tag="PC512_001766"
     CDS             complement(17465..18169)
                     /locus_tag="PC512_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HDF2441512.1"
                     /translation="MKDLILETKNLSKRYGEQMAVNNVSLQIERNSIYGLLGPNGAGK
                     STTLKMLVGLLRPTNGRIIFDRKPWKRESLAKIGSLIESPALYGNLTAEENLLVHTKI
                     LGIPKDKIYEVLEIVNLKNTGKKRASQFSMGMKQRLGIAIALLSDPELLILDEPTNGL
                     DPFGIQELRELIASFPKKGITVILSSHILSEVAQVVDNIGIINGGRLLFQGMPDPNEN
                     LEEFFTDVILKGGQNR"
     gene            complement(18424..18936)
                     /locus_tag="PC512_001767"
     CDS             complement(18424..18936)
                     /locus_tag="PC512_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441513.1"
                     /translation="MKKISQEKISTHIQEVPQEKIEQWKSLYEKYKSILKVNSKSVLE
                     IIEFLKRKYVIVEETSEEFKHVVINNIKLNKPFSQKISSDKELKPIVFTIPNEGNAKK
                     LYDTQEEIYSGCKIIVGMEFETGYVFVEGSDELNDEITSFKGLDKYDINNYYLVANYI
                     RCLKKYKLID"
     gene            19262..19519
                     /locus_tag="PC512_001768"
     CDS             19262..19519
                     /locus_tag="PC512_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441514.1"
                     /translation="MILNRAELFRGYSLNRFNEICNILSVNKIKYKYKVKNNAYSKKP
                     FFNEITLGNLGQKEDFSYEYLIYVHKDDYEQAESLINSKLR"
     gene            19662..20288
                     /locus_tag="PC512_001769"
     CDS             19662..20288
                     /locus_tag="PC512_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HDF2441515.1"
                     /translation="MKINIKSKLSEFIKQNNLFDDSRIISYLPNITIETDKIKTIMIN
                     EVVPTNTNDDFYSVDKDADYLKTTIPLFDSAGIKVSNINDILDMGIYITNAVKLPKSE
                     YTITRDTIKLHMPILEEEIKLFKNLEVVMLMGDVAKKSFNMITKKHIKKNVIPSISTY
                     KLRNNELYYDNLRVFPSYIMTGGNILIEKSKFEMASEDIKKMFEIING"
     gene            complement(20535..21314)
                     /locus_tag="PC512_001770"
     CDS             complement(20535..21314)
                     /locus_tag="PC512_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901940.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HDF2441516.1"
                     /translation="MNSKIYYFSGTGNSLVVSNILKETLNGSKEVIPLAIHRKENNID
                     INEDILVIVFPVYFADVPDIVKSFVEKLNFNINTHIYAIATCNGVAGHSLFTIDKLLK
                     KRGKKLSAGFLINMPGNALITPPDVEEERLKNQTNRVAEIAKCINNLEIGNIEGKNNL
                     KSHIDSVVLRLVGKNMQIATTKFFAENKCNRCGTCKRVCPVENISIVDKKPKWGNECE
                     RCLACFHWCPKEAINVKKSFLTNRKKYHHPDITVKDIFLDK"
     gene            complement(21382..21843)
                     /locus_tag="PC512_001771"
     CDS             complement(21382..21843)
                     /locus_tag="PC512_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2441517.1"
                     /translation="MGGARDYLNGGKMKDFEKLYEATTKLVSTSLKVKDDLKKMFKQN
                     GYDITTDHYALLRFLWEQDGISQIDLCEKSCKDKSNTTRILDVMKNKGLIVRKVDVKD
                     RRKFQIFLTDLGRELEEPLNEIASIYATETFKSISDEELPLFTDILDRIGK"
     gene            complement(21819..22496)
                     /locus_tag="PC512_001772"
     CDS             complement(21819..22496)
                     /locus_tag="PC512_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF2441518.1"
                     /translation="MIITVINGSPRKNGATSKVLTYLYKDIERLIPDVKINYFDLSEV
                     NPSYCIGCLNCYKMGKCINQNDKVEYIHDIITKSDGVIFGSPTYGSSVTGLFKVFTDR
                     AHMMLERLLYRKPCIAVTTYENARGSKAISFIKSMVLDSGGYVCGSLSIKTGFNQNPI
                     TEKVESKIQKVSKKFIYCIEEKKNPPVLSQIYNFIAINAVLKPMAFKDIEQYKGIIDR
                     WEEQGII"
     gene            22729..23115
                     /locus_tag="PC512_001773"
     CDS             22729..23115
                     /locus_tag="PC512_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2441519.1"
                     /translation="MKKLPHISEAEYQVMKIIWKYAPISTTEVIEKLVETSTWSPKTI
                     QTMLLRLVKKGALTYEKNSRVFVYTPLVKEEEYVATESSSFLNRFYNGTLNSMVLNFL
                     ENDKLSEDDIEELREILNKRTTKGDK"
     gene            23118..24917
                     /locus_tag="PC512_001774"
     CDS             23118..24917
                     /locus_tag="PC512_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaR1 family beta-lactam sensor/signal
                     transducer"
                     /protein_id="HDF2441520.1"
                     /translation="MYAPFFIRFLLSTLTLSILIVVILLAKKVFKKHISAKYQYNIGF
                     ILLIMLIIPFVPLKYINLGNVFNYLYTFNQLGSSTNRTSMIKNSSNSVINNSNALNDF
                     SVSLNQVNFDSLNILLLISWIIGILIMIAITIHCNIKIKNMKKSIQILKDEEIVFIFE
                     KCKKDIGINKDFILCKSPIINTPITFGYFKPHIILPDKSISKLSLKDIKYILLHELQH
                     FKNKDILINYIMCFLQILYWFNPLVWYAFKEMRIDREIACDISVLKKLNKDSHIEYGQ
                     TLINFVDNISRPSNLTLTSDIGGSKKQIKKRLLKIMDFHNESNTLKFKSILIFTLIAL
                     IVFGNIPKLSIMADINEKYRPTNEQTVYEDLSQYFKGFDGSFVMYDLKSKQYHIYNKE
                     KSKTRISPNSTYKIYSALLGLENGIITRNNSHIPWDGKHHSNSSWNEDQDLFSAMENS
                     VNWYFQTLDKKTGLKNIQTYLRQIGYGNYDVSGGISNFWLESSLKISPIEQVELLESF
                     YTNKFKFEDKNIETVKDSLLISKKDGVSLFGKTGTANINGKDVNGWFIGYVEKNENTY
                     FFATNIQSKDYSNGSSASKITLSILNDKKIYNP"
     gene            complement(25272..27146)
                     /locus_tag="PC512_001775"
     CDS             complement(25272..27146)
                     /locus_tag="PC512_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2441521.1"
                     /translation="MNKYNKIANELIKIIGEDNIISITHCATRLRVMVKDREIINDKK
                     VEKVDEVKGVFFTSGQYQIILGTGIVNKVYAEVEKMGLKTLSKKEQDELVKNNETGFK
                     KVMRTLADIFVPIIPVIAATGLFLGLKGCLFNDNVLGLFGMSSANIPLYIQTLVSVLT
                     ETAFAFLPAIIVWSAFKVFGGTPVIGLVIGLMLVSPILPNAYSVADPSNEIEAIMAFG
                     FIPIVGCQGSVLTAIVTAFIGANLEKWFRKHMPNVLDLIFTPFFVMLITMLVILLGVG
                     PIMHTIELKMVDIISLLIDLPLGIGGFIIGFTYPLAVITGLHHTYVMIETSLLANTGF
                     NALITLCAMYGFANIGTCLAFMKKSKNNQVKQTAVGAMLSQLFGISEPVLFGIQLRYN
                     LKPLIIMCASSGLGAAILSILHIQSNSYGLAVLPSYLMYIYDGYNLITYLLVSIFVVA
                     FCFIVTCLFGVPKEAINEDEDEELVFNENNENFVSPAKGKIVALENVPDETFSKKMLG
                     DGFAIDIIDGKIVSPISGKLETVVSSGHAFGIKGTNGEVLIHVGIDTVALNGDGFDVA
                     VKQGDMVKQGDVLVNVDLKRIHELGKSTLTMVLFPDGKKVNILDINKDVKIGQRICVE
                     "
     gene            complement(27151..28815)
                     /locus_tag="PC512_001776"
     CDS             complement(27151..28815)
                     /locus_tag="PC512_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HDF2441522.1"
                     /translation="MEKKWWQKEIVYQIYPRSFQDSNNDGIGDLQGIISRLDYLKNLG
                     ITSLWLCPIFKSPMDDNGYDISDYLDIASEFGSMEDLKELIKESKDRGIKIILDLVLN
                     HTSDEHPWFQEALKNPESPYHDYYIFKKGNDLPNNWRSVFGGSVWEKVENRDEYYFHS
                     FGKKQPDLNWENPILRSELYQMINTWSQMGVAGFRVDAITFIKKNLSFQSLESDGVDG
                     LVKCTKTVRNQPGIEKMLYELKENTFKKYDCMTVAEAAGISYDQLGDFIGEDGFFSMV
                     FDFKHADLDVASGSEWFKRISWTIPDLRKCILDSQMYVQEHGWAANFIENHDQPRATT
                     KYLLQYERNDDAVKMLGAMYFFLRGTPFIYQGQELGMTNFKRDTINDFNDLSSIDQYY
                     RSIDESYSEEEALEFVNLRSRDNARTPFPWADKENAGFSDTTPWLKVIENYKDINAQS
                     QINNSESILEFYKKMIKLRQDSEYSDCLIYGSIEPIDIESDDIIAYRRQLDLVVIDCY
                     YNFSDKPVEIRVEEKYDIVFQNLDDINLLNKTVRLKPFHAVLLKVR"
     gene            complement(28829..29650)
                     /locus_tag="PC512_001777"
     CDS             complement(28829..29650)
                     /locus_tag="PC512_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDF2441523.1"
                     /translation="MKLYKLLILDIDGTLRDEVYGIPESAKHAIRLCQKNHCSVVICT
                     GRSMGTIQDDVLSLGVDGYIAGGGNYIQYHGELLYNQSFNQRLIKEVVCLLKKREVAF
                     SIESQEKVFMNQKAKEIFETMNQLKGTNSCINKQHIQEKITYENNIEEYKSQDIHKIC
                     LWSNEKVFDEVKNILQDKMELAQRDISSQYYEIIQKDFHKGKAIKRLQERLGVTQKET
                     ICFGDGQNDVVMFQASDVTIAMKNSHQQLKDIATSICEDIFDNGIYKELKRRNII"
     gene            complement(29749..30513)
                     /locus_tag="PC512_001778"
     CDS             complement(29749..30513)
                     /locus_tag="PC512_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF2441524.1"
                     /translation="MKIEGLFNKYYNSFTANDKYICECILNHKEDCIKLSIDEFADKY
                     HISTSALSRFAQKLQLPGYSELRVIIRLNETEVEYKNQSKHQLMDCYNKVIDDIEKKD
                     CSIMFERMKKANRIIVFGEGYSQERVAKEMKRIFLPTGKIIYDVYGYDMIQALNHFIK
                     TDDMIFFISLNGDASTIIDFAKEMRMKGIYMVSITKMISNPLARLCDENLYIQSISIS
                     VDKQLDYDVTTPYFILIELLYIKYKMYLESEHIPRK"
     gene            complement(30510..31259)
                     /locus_tag="PC512_001779"
     CDS             complement(30510..31259)
                     /locus_tag="PC512_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF2441525.1"
                     /translation="MRLESLVNQNYDNLNENDKIIIKQILICQREYRNFSCEKIANEC
                     NVSRATLLRLCRKIGLDSFSDLKYLLKNNQLEFVNNDNNFHDVCENYRLLMNELQKIS
                     FQDICKIIYDAETIYIYGTGNEQKSLAQEIKRIFLSVGKCVIDLFDIGEIEFMRESFQ
                     KNDLFIIISLSGETKAGIEIAKFINNHIHTISLTRLDNNTIATLCEYNLYVETQKLDT
                     LQAISYEVVGAFYALLDLLHMNYIEYRRRKE"
     gene            complement(31763..32368)
                     /locus_tag="PC512_001780"
     CDS             complement(31763..32368)
                     /locus_tag="PC512_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2441526.1"
                     /translation="MKIKENVLMLDSTRGSNCFIVFDKEIILIDTGLPFMGKNIIKEL
                     KTLGIKLTDIKHILLTHHDVDHISNIKLLKEKTGAKVWAHVEDIPFIIGEKDRPGFKK
                     FIGKAISRRLIKDVEPYGENMQIGNIKIIHTPGHTPGHVCMIFEAVLFAGDLVKNKNG
                     NIVPYPNPWNWDYKKMVKSIRELDNLKYEWICMSHGTPCIK"
     gene            32547..33185
                     /locus_tag="PC512_001781"
     CDS             32547..33185
                     /locus_tag="PC512_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2441527.1"
                     /translation="MSELSKRDKEKIQRENEIIDKAEKLFCLNGFDNTTMNELAKEVE
                     YTKRTIYKYFSCKEDLFFAVVLRGYKRLWDNVKIESAKGKTGFEKIKLSYFAFHKFYS
                     VEPSLLCLMGMIGIVNSEKSDTDMLFKEKFFSFNKFMFDEIQGMFEIGKNDRSIRHDI
                     EIPTLMYSSIFTLTGFFNLLSVTGKSYLNNFNIDEEKFIETTLALLIDSIKA"
     gene            33317..33979
                     /locus_tag="PC512_001782"
     CDS             33317..33979
                     /locus_tag="PC512_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2441528.1"
                     /translation="MAKILLLEDDDTITFGIKTSLEKKNHTVCCYNTIAEAKKNFDKT
                     IDLILLDLNLPDGIGYEFCQYVKSIEDTPVIFLTVRDDEKDIIRGLDMGADDYVVKPF
                     LLSVLQSRINAVLRRTHSNTNNTITCENISLNKVEVKAYLDNVEVPLTAGEYKLLLSL
                     MENKNRAMTRTKLLEMLWDVDGNFVNDNTLTVTIKRLREKLKNPPCIKTLRGIGYRME
                     DS"
     gene            33979..35160
                     /locus_tag="PC512_001783"
     CDS             33979..35160
                     /locus_tag="PC512_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2441529.1"
                     /translation="MKTPRNINSTVVFIIFCLIVTFLLSVILTTITSFNEYNVLSKAL
                     GASYEYNPKSTESILKSLKNSSDKDFKTGNEILSKHGYSKSTFWSKNFFYFLVISFGI
                     ISTMATVIYIIKHRTNKQKLSRINNLTQYLEEVNLGKESVLLRCEDEFSHLEDEIYKT
                     VGELRCSKEFALKERQTLSDNLADIAHQLKTPITSMSLMAQLLSENCPDEEIDYINRL
                     TNQISRLERLVSSLLTLSKLDASTLIFESKLIDVHSLLTYAIEPIEGSLREKHQTFTI
                     EASPSVEFEIDINWTLEALLNILKNCSEHIEDGGYIVAYYSQNPLYVEIIIEDNGKGF
                     AQEELPYIFNRFYRGKNASKDSIGIGLALSKSIIERQNGTLHAENCHNGGARFIIKFY
                     T"
     gene            complement(35341..38001)
                     /locus_tag="PC512_001784"
     CDS             complement(35341..38001)
                     /locus_tag="PC512_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2441530.1"
                     /translation="MNILQEYTLDFVRRNKRSSIAIMLAILLTTTMMSSLCGLLYTMW
                     TDFIRLSIEKEGNWHGELFDYTYGSDLPLIENFSSVDDVMVKGQWYVGKINDEKRDYI
                     IYRNATSEYWNSMPEKDTIIEGRRPNNANEIALSKQYFENNPSVKIGDKITLPIGYRI
                     LNGKPLEPIAPKSKGESFKKISEATLTIVGKVDVSTSSVIPAYTALGYLDKTSIKPND
                     SITVYLRFKNIRDTYKELPKLAKSLGWKTNEYGKYNLKYNSNYLLKMLVFSPEQKASM
                     SSISKFSTPIMYLTIAIFTVAVFVMVIYNAFSLSANARLTQLGILSSVGASPKQIKRS
                     VVFEGFLLTIIPLPIGLFLGWLLCNRLIVYVNSVNYHTDVPEVVFTYGIPAFLPAVLL
                     TIVTVWISALIPARKVSKISPIEAIRQGDSVKIKKSHKYSLGKIFGIEGELASNALRA
                     RKKSYRTATISLTLSFLLLTCFLHIIANQEGAKAVYGSDNYKDQRDIAVYLENSEPIE
                     SAFIEKLDNTEGVKSSLYYQKMSASTWLTEKDASKELAKNGGFKSIVSSKKYSPIERD
                     GKFRIISNIIGLDDKSFTEYCRQISVDPKLFYNTKNPTSIVYNKEEDINRSTRRNKVY
                     IDYLNLSIGDNIKLNEKVYDEDKGDYTYNMKVGAITSTLPKIVDTSSKYTLMQIVPMS
                     MVQEISKNYDEVSRLRSNRLIGVFKVNNREDIPRVREKLESIYNKDYGSGDYSIEDVL
                     ESEKQKASGIKTMNLIVGFITGLLAMIGLSNVLATVSGNIRSRRQEFAMLRSVGLSPE
                     GIKKMLILEGLFLGITPLLLSIPVQIGIVYAFLRINEIYFIEYLPFAPISTIIGFTIL
                     ILFIVIASYMTGYKQLKNENIVESIKNETI"
     gene            complement(37998..38681)
                     /locus_tag="PC512_001785"
     CDS             complement(37998..38681)
                     /locus_tag="PC512_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2441531.1"
                     /translation="MEILKCENLTKIYGSNQTRVTALNNVNLSVQKGDFVSIVGASGS
                     GKSTLLHLLGGVDRPTSGKIYVEDTEISSLKEEALAVFRRRKVGLIYQFYNLIPTLDV
                     RKNILLPMLLDKRKVDEDRFSEIVSILGLSDRLNHLPSQLSGGQQQRVSIARSLIYRP
                     AILLADEPTGNLDRKNSEEIVDLLNLSNKRFNQTILLITHDEKIALEANRIVTMEDGV
                     IVSEKVVKK"
     gene            complement(39025..39978)
                     /gene="blaCDD"
                     /locus_tag="PC512_001786"
     CDS             complement(39025..39978)
                     /gene="blaCDD"
                     /locus_tag="PC512_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDD family class D beta-lactamase"
                     /protein_id="HDF2441532.1"
                     /translation="MKRKKNFIWIAILLVGVVMVMYYVGKKHNDINQKTDKNYIKSEL
                     NKSELNKSKIENNDKNKKEKINMVDYSDCFEGISGGAIFYNTKNKEYNIYNKELIETR
                     RSPCSTFKIVSTLIGLEKGVINSKESVMGYDGTEYPNKNWNKNLSLEEAFKESCVWYY
                     KKLIDKVDAKSVQNILDDLKYGNCDISEWEGDLKNGKGHLNGFWLESSLQISPKEQVQ
                     TMAKIFEGDTNFKKEHINILRDIMKIDINDKNINVYGKTGTGFDEKNKRVDAWFVGML
                     EREGDTYYFAIKSDDSNKEITGPKVKEIAINIIKKYYSVRE"
BASE COUNT        14226 a         6576 c         4932 g        14632 t
ORIGIN      
        1 ttaattaaat taaataaatt tatatttttt tgaaatcact taatatttta tataaaaatg
       61 aaaaagcacc tcattctgat taaaaatctt tctgagatac tttttaaaat attaaatact
      121 acatatagct tacataagtt taaaatttaa tctattataa aattacccta attgccaaac
      181 tttttaatat aaattttcca acatcctaca aatataatca atagatatag aatcctaact
      241 tacaccaata tatatttatt taaaatagtc ctaaaatacc tgtaatagct cccactacta
      301 tcagtataaa cattattttt attggagaaa gacctttttt taaagcaaag agtactaata
      361 aagtaagtac caaaggaatt aacccaggaa atatcttatc gagtaaatcc gtttgaagac
      421 taaatttaaa atcaccacta gtataactta ttggtgtaga taaattaata aacctaccta
      481 caagtccccc catgactaag gtacctagta tagaagcccc ttctataacc ttatttacta
      541 ttccaccttg aagtatactt tcaacggctt ttttcccata cttatatcca tttgtccaca
      601 ttccaaaaga aattgaagtc attattatat attgagctat tacaaataat ataggtcctg
      661 caattgatgc tcctccctca gttaaaccaa tacaaacagc caacactata ggagttataa
      721 ctccttgagt taaagtatcg ccaattcccg ctagtggacc catcaagcct gttttgatag
      781 cattcatacc atctccactt atttcatctg ctccattagc tttttcttct tccatagcta
      841 ttgttattcc atgtataaca catccacata taggttctgt gttaaaaaat gctagatgag
      901 tctccacttc ttgttttaac tcttccttat ctggatataa ttttttaagt actggcaaca
      961 ttgaatgtga aaaagctgtt gattgcaatc tttcataatt gtaattagat tgtgcaaaga
     1021 aaaaccatct taaccatgat tttattacat ctttcttgct taacgttttc ttagatactt
     1081 cattttttat atctgacata atattttccc cctcacatgt atttaagatg tagcactatc
     1141 ttttccgtac ttaattgaag taattgtaag agcaagtatt actccaataa cagatattac
     1201 tattatatct actttaaaat aaacagccat tagtattcct aatatgaaaa agggcatagt
     1261 aaacttgttt ccaatcaatt ttaaattcat agcaatccca agtgctggca acatagcccc
     1321 aattacatta aatacatgta acacattatc attcattact tccaacatac catctatcgc
     1381 atttggacca aaataaacaa ctaataatgc tggtataaaa ctcattgcaa ataacagtat
     1441 ctgtggtggt actatattta taaatgctac tctatcaaca ttcccttttt gaacctctct
     1501 atcagcccaa tgtgcaaaaa aagaatttac tgtcatcttt ccaatccaaa gtacagttgc
     1561 aacagttccc aatggtacag ctattgccat tgcagtactt acatctagct tagatgctat
     1621 agctaaagca gtacctacat atcctgcaaa agctgggtcc cccatctgag ctccccctgc
     1681 tgatataaaa cctagatata tcatatttat acctgctcct ataattgctc cttgaacagg
     1741 gtctcctaat ataattcccg ttacaaatcc agccaataga ggtctattcc atgtaaaaaa
     1801 tccaacataa gtcaaccacg gactccaaga aagataataa aaaattgcta ttaatactgc
     1861 ttgaattagt gaaatgtgca tattcttcct ccctattttc ttttaaagat ttacaagata
     1921 gtcttcttta caataatgtt cctacatcaa ttttctttgc atctggtact atttgtataa
     1981 agcatttaac atcttttgat attagctctc taaatatttc tttttcttca tctgacacag
     2041 atatattttt ataaaaactt tttctaccaa gccctgctcc catacctcca acattcaatt
     2101 cctttaaatc taccccgcta tttactaaac ctaagacagt tttagggtat ttgaccaata
     2161 ctattaaatt ttcatctcca ttatatgatt ttaagacttc agcacctgat tctacatcat
     2221 gtacttcaac cttaacagtt gatggagctg ccatttgtaa aacttgaact ataaatgggt
     2281 cctttactac taaatcatcc acgattacta tcctttttgc tgatgtaatc ttacaccaag
     2341 cagtaataac ttgcccatgt attaatctat catcaattct tgttaatgct atattactca
     2401 taattattcc tccagatttt taatttattt tacaacttta aaacagtttt aacatctttg
     2461 attcctgata tcccaacttc ctcacataaa ttcttcaagt cttttaactt catagtatct
     2521 ctgtttaaaa ataactctaa aagcataggt aaatttacac ctgtcaaaca ttctaactca
     2581 cataccttag caaatttatt tattataata gcagatgtat taaatggagt tccgccataa
     2641 aaatcaagca atactaaaac cccttcatcc ttatatttct caattccatc ttctaacttt
     2701 ctactaaact catctatgct gtcaccatgg tttaatccta aagtttctac attttcctgt
     2761 ttgcctacta ttaattcagc actttctaac attgctttag ccatatttcc atgtgtggct
     2821 ataattattc ctgccatatg aatcatacct ttcttaacct tttttatatg gattattatt
     2881 tagtactcta atctaattat ctatattaat cattatctta ccaaagaaaa tatccctttt
     2941 gtatactttt tcaaaataag ctggtacttc ttctaaattt attctatgtg ttactaattt
     3001 ttcaacattc atgtcaccct tttgcatatg atacaatcca gcactccatt cttttcctgg
     3061 gaatggaaag gagtttccaa accaagttcc ctttacagtt aattcacttc ttactatctt
     3121 ttcaaattgc tctctagtca aagctacatc cccatatggt acacctgcat acaatactgt
     3181 acctcccttt ttagctagca acagtacttg accacatgtc agtggagtac cagccgattc
     3241 aataacaata tctgcaccat ctccatcagt taaccttttt atttcttcta caatattctt
     3301 ttcttttgca tttatacaaa tatctgcccc taactctttt gccaagtcta acttctcatc
     3361 aaatacatcc acagctatta tttttgtaga accaaatatt tttgcccatt gtattgaaaa
     3421 taatcctatt ggacctgtac caagtactac aacagtatct ccaactttag cttctgacct
     3481 aaaaagacca tgtcctgcta tacatactgg ttctagcgca gcggcagtct cataacttat
     3541 ctcatctggt atttttatta aatttctctc tttcaccttt gtatactctg caaaacaacc
     3601 tccaagttct ttatttccta ttattgctac attattacat cttgaataca agcctttttt
     3661 acattcatca cattcaaaac atggcatagc tggacaaaca gcaactctat ctcctatttt
     3721 aaaactcctt acttctttac caacctgtgc cacttctcca gaaaattcat gccctaaaat
     3781 ttctccaacc atatgtggac ctgtctttga atattttgat atatcagaac cacatattcc
     3841 agctactttt actttaatta ttacatcatc tttttctaat atttttggta catccacatc
     3901 ctccactctt gtgtctctta taccatagaa tctaactgac ttcactatta accaccccta
     3961 ctttttattt gagaatatat ccctattgtt tatatgttaa atatctaaag caactttcat
     4021 gccaatatat gtaagcattg tattcatgca ttttataaaa ttatcattaa atgtgtgtca
     4081 aagtgtgtca aaagtttctt atattaaaac ttatgtgtgt caatataaac gacactaaca
     4141 ttttatatta gttctcttat tataagtttt ataaaatgta ctttttttgt tatttttata
     4201 aaattgttcg gaaatttccc ttctatttgt gatataatat taaatataag gtatcaatat
     4261 aaattttcat gcgaatatca gaactttttt gacactaatg ccttattcaa tataataatt
     4321 taactttttg gaggttgttt atgaaaaaag tgtatcaagg aaagactaaa gatgtttttg
     4381 aattagataa tggaaattac ttacttaaat ttaaagacga tgtaactggt aaagatggag
     4441 tatttgaccc aggcgaaaat agtgtaggtc taagtataga tggaattggt agagctaatt
     4501 tagagacatc tgttaagttc tttgaaattc taaacaatgc tggaattaaa actcattatg
     4561 taagtgctaa tttagaagaa gcaactatgg aagttctacc agcaaaagtt tttggtaatg
     4621 gattagaagt tatttgtcgt tatagagctg ttggtagttt cttacgtcgt tatggttcat
     4681 gtgttgaaga aggtgctaaa ctagattgtt acgtagaagc aactttaaaa gatgatgacc
     4741 gttgtgaccc tcttataaca tctgaaggtt tagaagcttt aaacattatg actcaagctc
     4801 aatttgattc aatgaaaagc atgactcaaa aaatttctaa catagttcgc gatactatag
     4861 ctgaaaaagg tcttgagctt tatgatatta aatttgaatt tggattctac aatgatgaag
     4921 taatcttaat agatgaaata gcatctggaa atatgcgtgt ttataaagat ggtgtaatag
     4981 ttgaccctat ggatttaact gctcttttat tagataaata gtatatacat ataatttaca
     5041 aatataataa acttataaat aagataagct atgaagtaaa gactttttaa atgttgatta
     5101 tttttaaaca ttttctcgcc tttaatttca tagcttattt aaattaatat actctaatta
     5161 gtagataata gctttaaccc tacaattccc accacaataa aacctataca tgcaattctt
     5221 gatatactaa taggctcatt taaaatagcc atgcctacaa tagctgtacc gacggtacca
     5281 attccagtcc atattgcata tgaagttcca agtggaagat gttttagtgc taatgacaaa
     5341 aaataaaaac ttacaatcat tccaacaaca gtaagtatac ttggagttaa tttagaaaat
     5401 ccatgtgaat tttttagttg aaaagcccaa aacacttcaa acaaacctgc aacaaacaaa
     5461 aataaccatt tcataaattc atccctcttt tcaaatatgt ctcttatttt tccaataaaa
     5521 taacctgaga aatattataa aatatctccc aggtttttgt ccttccgtgt tcacaacaaa
     5581 aactatgttg tgggttttat ctcggaccag accaatcatt aataattgcg gaaccctata
     5641 aaactctatt aattattcta ttttatctat aataatacta tcaacatata taaaaaaagt
     5701 caatatatgg gttccatata taataaaaat aacttttata taccttttaa tattcttatt
     5761 cacttctctc catacccatt tgggtcaatc taagaatatc taatttttat ttaatatgtt
     5821 ataataacat aaaaatattg aaaggagtaa tttctatgaa tttctataaa attgcagtat
     5881 gtcagatgat tactacagaa aataaaattg aaaatatcaa tcatgctgta gatatggtaa
     5941 cagaagctgc catcaatgga tctaaaattg tagttttgcc agaaatgttt aactgtccat
     6001 atgaaaataa atattttcct aaatttgctg aagaatatcc aggtgaaaca acaacaatat
     6061 tgagtaaatt agctgagaaa catggaattt atctagtttc tggtagtatt cctgagttag
     6121 aagatggaaa aatctataat acttgctatg tatttgataa aaatggagct ctaattggaa
     6181 aacatcgtaa aatgcactta tttgacattg aagttacagg aaaagttagt tttaaagaat
     6241 cagatactct tacagctgga aatgatgtta ctgtaataga taccgaatat ggaaaagttg
     6301 gtatagctat ttgttatgat attcgtttcc ctgagttatc acgtttaatg gctcttaaag
     6361 gtgctgaaat cgttatcttg cctgctgcat ttaatatgac tactggtccc gcccattggg
     6421 agttatctat aagaatgcgt gctttagata atcagatatt ctatgttggt gctgcacctg
     6481 ctagaaatat gaatgcttcc tacatagctt ttggaaattc aagaatttca gacccttggg
     6541 gaagaataat tgctcaagct gatgaaaaag aatgtattat ttatgctgac attgatagag
     6601 atttaattcc tgacataaga caacagttac cacttcttaa gcacagaaga actgatttat
     6661 atgaacttaa tactttgaaa taaaacagaa cataacccca taaatcataa attaagtgtt
     6721 aaaaaaattt atggggttct cattaatttg atttaaaatt aatttcataa aaataatact
     6781 aatattaatt taattaaata atactaataa ttactaatga ttatgctaat tatcagcatt
     6841 tactaattta atcactatta gttatttctt ttattaaata tctttacttt ttttacttat
     6901 tatgtcttct agctttacat ttggattata gtatttcttt ctatttttag tcacatcttt
     6961 ctattgaatt acttgcttaa aacaccaatg cacacattcc agacaatgtt cacaattatg
     7021 taaaaatctt gctctacctt cttcaatgtt gatattatct ctcctagttg atattatctt
     7081 tcctaaaatt tcttttaatt aaaaaacaac attcgttgat atatcgagta tattttaagc
     7141 aactgaaaaa aacaataata attgatatat caactaatta atgtagatta attcattttt
     7201 ataatttata tactttttaa ttaatctacc tttttaatta aaattcttcc tttctattta
     7261 tccattttaa acttaaatta taagatttca tcagctgtgt ttttgcattc caataagtat
     7321 taaatatcaa atatatattc tattaaaatt tctaataatt tcatccttga tttatttaat
     7381 atataaaaat atactaactt taatgattaa gttttgaaat ataactaaga atttgagatt
     7441 ttattgagat ttttatacta aagtatacat actatacaag cttaatttag aagggagcat
     7501 tcttatgaac aataaaatac tcgtcgtaga tgatgaggaa ggtataataa cactcttaaa
     7561 agattacttt gaaatgaatg gttatgaggt ttacactgct caaagtggaa aaggcgcatt
     7621 aaaaaaaata tccaaaaatc cagatattat tctacttgat ataaacatgc ctgaaataga
     7681 tggaattgaa gtttgtaata gaattagaga ttatgtatca tgccctattc tatttcttac
     7741 agctagaatt gaaaatactg acaagataaa tggttttcgt gctggtgctg atgattatat
     7801 tgtaaaacct tttgatttag acgaacttgg agctagagta tctgctcatt taagacgtga
     7861 aaaaaggaag tcaaatcaaa ctaaaattaa attttataat gatttaacga tagattacga
     7921 aaaaaggtta atttgtatag ataataatca gatttcactt tcaaaaaagg aatttgatat
     7981 agtagaactt ctctctatga atcctggaca agtatttgat aaagaaaaaa tctatgatag
     8041 agtctgggga tacaatagca atggaaatag tgatgttata atggaacaca ttagaaagat
     8101 acgaatcaaa ctatcaaaac atactctgga aaattatata gaaacagtct ggggagttgg
     8161 ttataaatgg ataaaataaa taatatgtca ttaaaaaaag ctttctttgt tcttacttta
     8221 tcttcactaa ttatagcatc aacacttact actttctcat acattttgct taataatcta
     8281 tataattcta tacaagataa gtatttaaaa acacctataa atacgggttt tataaccata
     8341 gttcaaaaca atgtgaacca atttagtgat tatgataaaa cgttacttaa tataatcaac
     8401 atacttcagc ttgtacttcc acttatattt tttataggac ttttattatt agctgatata
     8461 attttttaca aggtaaaatt aaaaacaccc atagaaatac tcaataaagg tgcaatggaa
     8521 atatccaaca acaatttaga cttttgctta gagtataata ataatgatga attaggtaat
     8581 ctatgtaatg cttttgaaaa aatgaggtct gaactaaata aaaacaacat aaagatgtgg
     8641 actatgatta atgatagaaa acaacttaat gctgcttttt ctcatgattt aagaaatccc
     8701 ctaacagttc taaaaggtta ctcaaactat ttaacaaaat acataccaac aggtaagctt
     8761 agtgatgaga agattttatc aaccacacaa cttatgtctg agcatattaa cagaattgaa
     8821 tactatgtag aaaatatgag taatgctcaa cgattagaag atttagttgt ttcaaaatct
     8881 atgtcgaata taaacaagtt tatagaaaac ttagatgaaa atatatctat cattgctaaa
     8941 caagaaggaa aatcttttac acttaaaagt caaataaata atataaatct attttttgat
     9001 gaaaatatca ttcttagagt cgtcgaaaat ataatatcga atgcttttag atatgctaga
     9061 aataatgtat ccatacttat atatcttgaa caagaactcc ttacctttgt aattgaagat
     9121 gatggtatag gatttagtaa ggaatctcta aaattagctt taagaccttt ctatagagat
     9181 aagactttaa atgacagcaa tgcacacttt ggtatgggtc tttatatctc aaaaatatta
     9241 tgtgaaaaac atggtggctc tatttctatt gaaaataatt ctactaacag tgctaaaatt
     9301 actgctaaat tctcaacaag aaattaaaat gattttgtaa gctttcactg ctattatata
     9361 aaatttgtta gtttagaatt tataaaatgt atttcaattt ataaccaata tatatactat
     9421 tttgtagaaa ttgtaagagt tgcttcaatt ataatatttt ggcaaaaggc atttgaaaca
     9481 ataatagaaa tatatattta aatatgtaga atagtatgaa attagaattt tggaggtgat
     9541 tatattaaaa gttttgctaa taatattaca ttctctcgta ttgtgtttgc attgctaatg
     9601 cttagtttta cattctgttc actgcctttc tggatatgtt atttttggtg tggaattagt
     9661 gatatatttg atggtcttat tgcccgaaag ttgagacaac aaagtggaat aggtgcaaag
     9721 ttagatagta ttgctgattt cattttttcg gttacaattt tggttactgt cggaaaaaat
     9781 attgctcttc ccatgtatct atggtggtgt attgttgcaa tagcattgtt acggttgatt
     9841 agttacagta ttggtttttt taagtatcgc acattttcat cgcttcatac tttgatgaat
     9901 aaaatcactg gaatttctat ctttgcgttt ccattactct atatttgctt tggtcttgat
     9961 gttgcaggaa ttatgatatg tatcgtggct tttctttctt cttttgaaga aatagcaatt
    10021 atgataaaat caaaagaatt aaatcgtgat ataaaaagta tatttatgtg aaaacttaga
    10081 atttgtgaca aaaataattt atataataat gaggaagtaa aacataaaaa attatccaca
    10141 agtttatgtg taaaatagtt ttaaagcaat agagttgtat tgtaaagcct ttagtgcata
    10201 aattacattt taaattaaaa atgatactga aactgcttat cagcactgcg aattatccgc
    10261 aaatagtgaa gactttttag atttaagcta aaagttggga aaaaattgag ttttaaaact
    10321 tacactcttc ttatatagaa aaggagagtg ttttttatga ttataaaagc aaaacaatta
    10381 tcaaaaatat atggttctaa taacaataaa gttatcgcac ttaataatgt aaatttagaa
    10441 ataaactcag gtgaatttgt ttctgtaatt ggaccttctg gaagtggaaa aagcacactt
    10501 ttacatattt taagtggatt agataatcct acctctggac aagtgttact tgatgataaa
    10561 gatatatata aacacactga aaaagaacta tctgcactta gaagaaaatc ctttggattc
    10621 gtctttcaac aatttaatct tttacctgtt ctgacagcat ctgaaaatat ttcaatgcct
    10681 gtacttctag ataaaaaaca acctgataaa gaatatttaa atgaaatctc atcattactt
    10741 ggaattgcag atagactcaa tcatcttccc catgaacttt caggtggtca acaacaaaga
    10801 gttgcaattg ctagagcact tattgcaaaa ccagatataa tatttgctga tgagcctaca
    10861 ggaaacttgg acagtaaaag tggcagtgaa gttatgaatc ttcttataaa aacttcaaaa
    10921 cagtttggaa agactttagt ggtaattact catgatgata gaattgcaaa acttgctgat
    10981 agaaaaattt caattattga tggtgttctt atggaggtga aatagaaatg aagaattacc
    11041 tttcactttc aataaaagaa ttaaaaagcc agaaacttat gactacattc atcattatag
    11101 caatagtact atcaactatt atgacaactg tggttggaca gtcaattggt atcctacaaa
    11161 atttaagaat tgaacaagcc cgttctttta acggtgatag acatgtatcc tttcaccaac
    11221 ttactaaaaa tcaagttgat gacataaaga aagatgatag agtttatcaa gctggtactt
    11281 caataactct tggcagtagt aaaataaagg attctggtat ctctgtactt gtaaaagagt
    11341 atgataaaac aggactttcc aactacccca aattaatgaa attaaaatct ggaaatttgc
    11401 ctaaagataa aaacgaaata gccttagatg aaaacacact aaagcttatg ggtataaaac
    11461 caagactagg agtgactata cctatgaatt tagatatttc acttttaaat gatacaatac
    11521 caccatataa ttacacagct aactttaaat tgagtggtat tttagaggat gattatacag
    11581 gatatgtaag tggtatagta aacggtattg taggcaaagg tgcatcagaa aatctattac
    11641 ctaagagata tattttatcc tctttggatt ttaaaataaa acagcaagag aagtttcaag
    11701 aaatagtaaa tcaattagct aaaaaaataa atctttctca caattcaatt caatataatt
    11761 ggatttactt aaatgctctt aaaatacagt ttgaaaaaga tgaaaatagt tctaatagtg
    11821 atggtatatc tatgattata ttggtatctt tatttgttgc cttattggtt ttactggctt
    11881 ctggacttgt aatctacaat attttaaaaa tctctgttac aaagaaaatt aaggagtatg
    11941 gatgtttaag agcaatagga gctgaaccaa accagatata taagatagtt attttacaaa
    12001 tcttaatttt atgtactatt gccataccta ttggagctgt aattggaatt atatcttcta
    12061 aaggcataac tggaatggtc actaatatct taaatccaga tatacttcta gcaaatgata
    12121 ataaagaaat tactgagctt atacataaaa acacaacagc atatatattc ccattagtat
    12181 taagcactag tatatctttg attttttcac ttatttcagc attaccatca gcaatatatg
    12241 cttcacatgt ctctcccaaa attgctatgg ctggcagtac taccaaaatc aaaagaaaaa
    12301 ttaaacgaga aaaaacaata aaaaactttg aaagacatct agcctggcta aacttaaaaa
    12361 gaaataaagg aagaactata ataaccatac tatcattatt tatgagtata acagtattcg
    12421 ttgcactgag tgagttctct aatgtattag atgtatctag gtcagtaagt aatttaaaag
    12481 aaggagattt ttccttaaca aatgaaatat ctggttttga taagtcaata ctagataaaa
    12541 tagataaaat gaaaaacgtc aatcgcactt cctttataaa gtactctgaa tacaaacagg
    12601 gcgaaataga tacagatata aattttgaaa atagtggtga gatgttaaaa atcattggaa
    12661 ttgatgagca aactttaaaa gacttaatgc cttctattac agattctata ctagaagact
    12721 ttaaaaatgg ttctatctgt tttataaaaa atccgattgc tatttctaca ccaggtgtaa
    12781 aaactagaca tacaaattta aaacctaaag ataatatcac aattaacaaa aaacaactag
    12841 atatatatag tacagtagat aaaatgttct ttttacaagg taatggctgg ataaatggtg
    12901 ttgatgttat tgtatatgat tctgtttata acaccttgac aaataaaaac aagttcaacc
    12961 agataaatat ttatgctaaa gataaatcaa aattagaaca aataagattg tctattgaac
    13021 agatttgtga aaataatcct ggctctcatt ggatatcata tattgaatca gataaacaac
    13081 ttaaagagag ttttaaacaa atagaatttc tagcatgggc agttatatta tttgtgggat
    13141 tgattggtac tttaaacatc attaacacaa ctcatacaaa tataaatact aggactaatg
    13201 agattggagt taaaagagct attggtatga gtaatagtag cttatataag atgtttttat
    13261 gggaaggtgt ttattatgga atttttgcta ctatatttgg ttcaattgct gggtatgtca
    13321 gtgctattat tataaacatg gcaactatag aaaagcttga ttttactaat ataccaatta
    13381 cttcaatttt acaagctact attatttcta tacttgcatg tattatagct actcttattc
    13441 cgttaagaaa agttaaaaag atgaatataa ttgactgtat agatgtcaat ttataactat
    13501 tttacagata ataaataaat taaattatca atgactgtct ctattttctt ttaaatctaa
    13561 ctaataaatc tttttaacta taatataagc tttaaaaaag gcctgtctca aaatagagat
    13621 aagccttttt tcattgtcga aataatgaaa atatatttaa cttcacaaaa aaagagtgcc
    13681 tcacgaatta aaaatttcgc tttgagacac tcccctttaa tttaaaatat atagttaaat
    13741 gctatgccaa aatttcacac atgctccacc tgattttgaa ttttctattt taacagaacc
    13801 tccaagctgt tccactaatt gttttacaat gtaaagccca agaccagaat gtcctccttt
    13861 agtctgccta gcttcatctc ctcgataaaa cttatcaaga gcctttttta aatctttaga
    13921 gctaaaccct ctaccagaat cacaaatctc ataagaaata caattttttt catcctttac
    13981 agtaatacta atattaccac ctgatggagt gtattgcaga ctgttggata tgatattatc
    14041 aaaaattcgt gtcaacctat ccacgtcgat ttgaattggg gattgtatat tcccctgcat
    14101 tttcaatata agttcaactt ccttttgatg agcctgtaat tcatagtctt gtaccttttg
    14161 cctcaaaaat tcaggtaaat ttataggaac aagatttaat tgtatatttg acttttctaa
    14221 gtcagacgta tattgcatct tttggacaag agcagcactt ttttctgtat tttctcttat
    14281 cactgtaaga tacctatgaa gtttttcatt gtcatctgta ttattaccaa taagtgcatc
    14341 tgtatatccc aaaataatag aaagaggaga ttttaaatca tgtgctagag cttccaccat
    14401 ttcaacacgt tcctgctcca tcttccactg tgcagataaa gagcctttta attcgtcttt
    14461 catttcagaa aatgcactac aaagtttacc gagttcatta tctgaataat agtcgatttc
    14521 aaaatcaagg tccttttctt ttatcttctt ggacgcatca atcaatagat gtaatggttg
    14581 attgatattc tttacaaagc gcttagaaag ccatctagta aaacccacga tatatagaaa
    14641 tggagaaaac agagccatta taataactgc aaatacaaat ctccctctaa tatttgcaaa
    14701 ggtgattttc acttggtaga atagaataac agctccctca atctttccat tatccccttt
    14761 gattggaaca gtatggatat aaccaccttt acgaacagtt ttattgataa aattattaaa
    14821 taattcttct tttgttttaa atagtttttt ggggttagta ccatataaaa tattgccatt
    14881 attatccaca acttgatata gcatatcatc cccacgaatc gttcttttta aaccttcttc
    14941 attcgattgt gataacaaag ttatgttttt ttcattgatg tatttttcaa ttctaggaac
    15001 ttgtcgctca taatagtttg gtggatagat atccttattt aaggaatgaa tatacaaata
    15061 gagagcaaat acataagtaa tcactgtggc aactatactg gctattataa taaaaataaa
    15121 agtatgtcta aattgggtaa taagggattg atttttcatt taataacctc tctctcttta
    15181 cattttattc cacttatacc caatacccca aactgtggaa atatattctt tttctggtgt
    15241 cacagcagaa aacttagctc gtattttttt tactcgttca acaacagttg aggaatcacc
    15301 ttcagaatca cacccccata ctttttcata gatttgttct cttgagaaaa cttgtcctgc
    15361 atggagtgct agtaattcaa caatatcata ctctattttt gttaaatcaa tattcttacc
    15421 atcaatttta attgcacgtt ccttcatata taagcataac ttcccaaaat acaaagtaga
    15481 tctcttgttc tcttcattga tatactgtga acgcttttcc ctacgcagat tagcttcaat
    15541 ccttgccata agttcacgca gtccaaatgg ctttgttaca taatcatccc ctccaaaggt
    15601 caaccctttg attttgtcgg tttctgattg ctttgcactt aaaaatataa ttgggcataa
    15661 aacatcatct ctaattgcct gacatacctc aaatccattc attttaggca tcataatatc
    15721 cagtataata aggtcaggct cctgttttga taactctata cctgcctgac catcataagc
    15781 tatcaacact tcatgtcctt ttgccttcaa ttcatcctca agtagcatta ctaggtccat
    15841 ttcatcatca ataatcaata ttttactcaa tataacacca cctttctctt atgggaaggt
    15901 cagtattaaa acaatattcg tctactaata acttttcctt ccctcccaca ttttaaacca
    15961 aataacgcct cctatcaaga atataatcaa acctattgct actactataa gctctatact
    16021 agctgtttgc atcactttag agtaaaatgc ctcagttgaa atagttccag cttctttaat
    16081 aaaataaatt cctggaagca tacctagttt tactggccat gtccatggaa caaatgccca
    16141 tactttttca ccaacgctag ttaatccaag tattgctgcc atcaaaattc caccgatact
    16201 aataccaata gatgcaccca taccccatgc aaaactcacc caaagatgaa tagctaatag
    16261 tggaagtgtc ccaatcacca caagtcctgc tgctgacagg aataaccata ttgttgctcc
    16321 agatggcact gcaatactca ttcctatgca aagtatcaac gtagcaataa atgtgcatat
    16381 agttaggcaa aacagaagaa aaagaaattt tcccagatat aatctaacac gagaaatacc
    16441 tacacataaa aaaccattaa aatttccagc aagctcttcc tcctgcacta taaatcctgc
    16501 taaaatacct actccaatag gaatgatgaa tacagtccat actgtaaaaa atccttcaaa
    16561 agcaaattct tgtgtacttc cagatttagt tgtgagataa aaaaccacac ataatgaaaa
    16621 aataataggc ataaaaagag taagccactg gacagctgtc ctctttgctc gaagccattc
    16681 tgatgataat agctttatca tttgtcatcc ctcctattga accaagctgc agtaagtgct
    16741 gttaatacta taaacacaac caaagaaaca acaatcccaa taggaatcac tgaagtattc
    16801 aaaagtgggt ctccagcttc taatatagta ccgttaggat gtatgttgat gattgggcat
    16861 accattctaa ctgcccaact ccaaggtact gcaatccaaa atggttttgt cgcagcaagg
    16921 acaccaaata tcatacctaa agctccaact cccatactta ggaacatacc tttccatgta
    16981 gctagccata gctgaagtgg aagtatagca agagaaacaa cccagcatac aatacttgcc
    17041 cctataatct gtccaaaagg aactggacca gctttcaata ttaaaccagt tataattgtt
    17101 acgactatta aaactagcgt tgaaataaaa ctgtagactg ccatagctat aactttatta
    17161 atccaaagtg tcataggaga cacattgtgt gtacgtaaag cacgataatt tccagctttt
    17221 ttttcctgga aagctaccaa agtagcaaac aatgcaaatc caataggcag aaataaaaat
    17281 gaccaccagt taaaaattaa tgctaaaaga ctttgccacg cccaagaagt tgtttgagat
    17341 aatggatttt gcatgagtgt tgattgcatt ataaatgcat atgctgcaaa agacactggg
    17401 aaaaaaacaa taagtttacc cataaatgtt cttttatact ttaaaagttc tgattgtaaa
    17461 gcattcatct gttttgtcct cctttaagaa taacatctgt aaaaaattct tctagatttt
    17521 cattagggtc aggcattcct tgaaataata gtcgtcctcc atttataatt cctatattat
    17581 ctacaacttg agcaacctct gatagaatat ggctagaaag aattacagtt ataccttttt
    17641 ttggaaaaga agcaatcaat tcacgcaatt cttgaatgcc aaaggggtca agaccattgg
    17701 ttggttcatc tagtattaac aactctgggt cactcaaaag tgcaatagct attcctaacc
    17761 tttgtttcat acccatagaa aattgtgaag ctctcttttt acctgtattt ttcaaattta
    17821 ctatttccaa cacttcataa attttatctt taggtattcc caatattttt gtatgtacta
    17881 acaaattttc ctctgctgta aggtttccat acaatgcagg ggattctatt aaagaaccta
    17941 tttttgcaag agattctcgt ttccaaggct ttctatcaaa aataatacga ccatttgttg
    18001 ggcgaagaag accaacaagc attttaagtg ttgtggactt tcctgctcca tttggtccta
    18061 aaagtccata tatactattt cgttcaattt gtagagaaac attgttaact gccatttgtt
    18121 ctccatatct ttttgataag ttttttgttt caagaattaa atctttcata ttaatttctc
    18181 ccttcttgta ataccttaaa tctgttacta agagaatact aacatgaaaa aataacaatt
    18241 ctataacacc tactaatttt aataaaattt aaaataaaaa atagagttac caattttatt
    18301 ttggcaactc tatttaagtt tatgttttac agttatatta gatttaagct tagtttcatt
    18361 atcacactaa cttcaaattt actctataat ccttaaatca aacactaatt tattaatcaa
    18421 acactaatct attaatttat atttctttag acatctaata tagtttgcta ctaaataata
    18481 attatttata tcatatttat ctaatccttt aaaagaagtt atttcatcat taagctcatc
    18541 actaccttct acaaaaacat aacctgtttc aaattccata cctacaataa tcttacagcc
    18601 actataaatt tcctcttgag tatcgtacaa tttttttgca tttccttcat ttggaattgt
    18661 aaatacaata ggttttaatt ctttatcact ggaaatcttt tgtgaaaaag gcttgtttaa
    18721 cttaatatta ttgataacta catgtttaaa ttcctctgaa gtttcttcta ctattacata
    18781 ttttcgcttt aaaaactcta ttatttctaa aacagactta gaatttactt ttaaaatact
    18841 tttatatttt tcatataaag atttccactg ttcaattttt tcctgtggta cttcttggat
    18901 atgtgtactt attttttctt gagatatttt tttcaattaa actctccttt caatacttaa
    18961 atatccttat aaatctcaca tgactaaagt tacaaggttc ctacttaata gaattttgca
    19021 tacttaaata tgtcttatta attctctaca ggatatctcc gtagttccta cgattcttac
    19081 ataagttact tattttaaat tgttattagt tagattataa aaattattta ttttatcact
    19141 aatataatac tcttaaaaac tttacaaatc aatttaaatt tgctaccttt tatttataac
    19201 aacttatagt acatttctcc tatgcttttc aatatattac ttttaaaagg aggttttcat
    19261 tatgatttta aatagagctg agcttttccg aggatattct ttaaatagat ttaacgagat
    19321 atgcaatata ttatcagtaa ataaaattaa atataagtat aaagtgaaaa ataatgctta
    19381 ctctaaaaaa ccttttttta atgaaataac acttggcaat ttaggccaaa aggaagattt
    19441 ctcttatgag tacttaattt atgttcataa agacgattat gaacaggcag agtctctaat
    19501 aaattctaag ttgcgataga ttatctataa aacatgacat tctgttgtca tgttttatat
    19561 gttattatac tttcaaatat gctactatat tttcaaaatt gtgtgcttta aaactagctt
    19621 tttttagtaa tttaaagctt aaaactaagg agactcgtta tatgaaaata aatataaaat
    19681 caaagttaag tgaatttatt aaacagaaca atctttttga tgacagcaga ataatatcct
    19741 atcttcctaa tataacaata gaaacagaca aaataaaaac tataatgatt aatgaggttg
    19801 tcccaactaa caccaatgac gatttttata gtgtagataa agatgctgat tatttaaaaa
    19861 ctactattcc tttatttgac agtgcaggaa taaaagtatc taacataaat gatatcctag
    19921 atatgggtat ctatataact aatgcagtaa aacttcctaa atcagaatat acaataactc
    19981 gtgatacaat taaattacat atgcctattt tagaagaaga aattaaatta tttaaaaacc
    20041 tagaggtagt aatgttaatg ggagatgttg caaaaaaatc ttttaatatg attactaaaa
    20101 agcatataaa aaagaatgtc atcccttcca tttcaacata taaacttcgt aataatgaac
    20161 tttattatga taatttaaga gtatttccat catatattat gactggtgga aacatactga
    20221 ttgaaaaatc aaaatttgaa atggcatcag aagatataaa aaaaatgttc gagattataa
    20281 acggttgata ttacaaaata ataaaaacta atataaaata aaaagtgcct caaaaacttc
    20341 tatttatgag gcacttttat tttatattag tgtaactata tactattaac ataatttatt
    20401 atttatattg ttccttttaa tctctattcc atttagtcta ggtaacatta ctctttacaa
    20461 gattacttta tatttctttt atatctctaa cgtttttatt taataaaaca attattaata
    20521 caagtcaaat atatctattt atctaaaaat atatctttta cagtaatatc tggatggtga
    20581 tacttcttcc tattcgttaa aaaagatttt tttacattaa tagcctcttt tggacaccag
    20641 tgaaaacaag ctaggcatct ttcacactca ttaccccact ttggcttttt atcaactata
    20701 cttatattct ctacaggaca aaccctttta catgtcccac atctattaca tttattttct
    20761 gcaaaaaatt tagtagttgc aatttgcata ttcttaccta ctaaacgaag tacaacacta
    20821 tctatatgtg actttaaatt gttttttcct tctatatttc caatctccaa gttattgata
    20881 cattttgcaa tctcagctac cctattagtc tgatttttca atctttcttc ttcaacatct
    20941 ggaggtgtta tcaaagcatt tccaggcata ttgattaaaa aaccagcaga taattttttc
    21001 cccctttttt taagtaactt atctatagta aataaactat gtccagctac cccattacaa
    21061 gtggcaatgg catatatatg agtattaata ttaaaattta atttctctac aaaagacttt
    21121 actatatcag gaacatcagc aaaataaaca ggaaaaacaa ttaccaatat atcttcattt
    21181 atgtctatat tattttcttt tctatgtata gctaagggta taacttcttt acttccattt
    21241 aacgtttctt ttaaaatatt tgaaactact agcgaatttc ctgttccaga aaaataataa
    21301 atcttactat tcattcttat ccctctttct atatttctac atcatcaata gttaaaaagt
    21361 ctcttaaaat aggatttata tttactttcc aattctatcc aaaatatcag taaacaaagg
    21421 caattcttca tcagagatag atttaaatgt ctctgttgca tatatacttg caatttcatt
    21481 taatggttct tctaattctc tacctaaatc tgttaggaat atttgaaact tacgtctatc
    21541 tttaacatct actttacgga caattaatcc cttatttttc ataacatcta agattcttgt
    21601 cgtattagat ttatccttac atgatttttc acataaatct atctgagaaa ttccatcttg
    21661 ctcccataga aaccttaata acgcataatg gtcagttgtt atatcatatc cattttgttt
    21721 aaacatcttt tttaaatcat cttttacttt taacgaagta cttactaact tagttgtagc
    21781 ttcatatagt ttctcaaaat ctttcatttt acctccattt aaataatccc ttgctcctcc
    21841 catctatcaa ttattccctt atattgctca atatctttaa aagccattgg ctttaaaaca
    21901 gcatttatag caataaaatt atagatttga gaaagcacag gtggattttt cttttcctct
    21961 atgcaataaa taaatttttt agataccttt tgtatctttg attctacttt ttcagttata
    22021 ggattttgat taaatccagt ttttatagat aaactaccac aaacataacc tcccgaatct
    22081 aagaccatgg attttataaa agaaattgct tttgaaccac gtgcattttc atatgtagta
    22141 actgctatac atggcttacg atacaataat ctttcaagca tcatatgtgc tctatctgta
    22201 aacaccttga aaagtccagt tacactactt ccataagttg ggctaccaaa tataacacca
    22261 tcactcttag taattatatc atgaatatac tctactttat cattttgatt gatacacttg
    22321 cccattttat aacaatttaa acaaccaata caatatgatg gattgacctc acttaaatca
    22381 aaataattaa tttttacatc tggtattaat ctttctatat ctttatacaa gtaagtcaaa
    22441 acttttgatg tagctccatt ttttctaggg cttccattta taactgtaat tatcatttct
    22501 atatctcctt tttagttgtt atatcaacaa taagtatatc aactatattt ttagctgtca
    22561 atataaacca tttatttaaa gctatactta cacagcttaa ataaaagttt tatttaacta
    22621 catgtgctta tttaatcaac tataaatgaa ttatttttaa taattgacaa actaaattaa
    22681 tgataatata ctttatgtat tacaaatgta agtagaagga ggtatagtat gaaaaagtta
    22741 ccacatattt cagaagcaga atatcaagtt atgaaaatta tttggaaata tgctcctatc
    22801 agcactactg aagtaattga aaagttggta gaaacaagta catggagtcc taaaacaatt
    22861 caaacaatgt tattgagatt agttaaaaaa ggagctttaa catatgaaaa aaatagcaga
    22921 gtattcgttt atactccact tgttaaagaa gaagaatacg tagctacaga aagtagttct
    22981 tttttaaatc gtttttataa tggtactctt aattctatgg tactaaactt tttagaaaat
    23041 gataaactat ctgaagatga tattgaggaa ctgagagaaa tcttaaataa aaggacgact
    23101 aagggggata aataaatatg tatgccccat tctttatacg atttttactc agtacattaa
    23161 ccttatcaat attaattgtt gtaattttac ttgccaaaaa agtatttaaa aaacatattt
    23221 ctgcaaagta ccaatacaat attggattta tattgcttat aatgttaata attccatttg
    23281 tccctcttaa atatattaat cttggaaatg tatttaacta tttatatact tttaatcaac
    23341 ttggaagcag tactaatagg acttctatga taaaaaatag ttcaaattct gtaattaata
    23401 actcaaatgc attaaacgat ttttcagtat ccctaaatca agttaatttt gatagtttaa
    23461 atattttatt actaatatca tggataattg gaattttaat catgatagct attactattc
    23521 attgcaacat taaaataaaa aatatgaaaa aatcaataca aattttaaaa gatgaggaga
    23581 tagtatttat atttgaaaag tgtaaaaaag atattggtat aaataaggat tttatactat
    23641 gcaaatcacc tattataaat acacctatta catttggata ctttaaacca cacattatat
    23701 taccagataa gtctatatct aaattatctt taaaagatat aaaatatatc ttacttcatg
    23761 aattacaaca ttttaaaaat aaagatatac tgataaatta tataatgtgc tttcttcaaa
    23821 tattatattg gtttaatcct cttgtatggt atgcatttaa agaaatgcgt atagaccgtg
    23881 aaattgcatg tgatatttca gttttaaaaa agcttaataa agatagtcat atagaatatg
    23941 gacaaactct aataaacttt gtggataata tttcaagacc atcaaatctt acacttacat
    24001 cagatattgg tggttcaaaa aaacaaataa aaaagcgact attgaagata atggattttc
    24061 ataatgaatc aaatacgtta aaattcaaaa gcattttaat ttttacattg atagctttaa
    24121 ttgtatttgg aaatattccc aaactatcta ttatggcaga tatcaacgaa aaatatagac
    24181 ctacaaatga acaaactgtg tacgaggact taagtcagta ttttaaaggt tttgatggaa
    24241 gttttgttat gtatgattta aaatccaagc aatatcatat ttacaataaa gaaaaaagta
    24301 aaacaagaat ttctccaaat tctacttata agatttatag tgccttattg ggattggaaa
    24361 atgggataat aacaagaaat aattcacata tcccttggga tggaaagcat cattctaata
    24421 gttcttggaa tgaagaccaa gacttatttt ctgctatgga aaactccgta aactggtact
    24481 ttcagactct agataaaaaa acagggctaa aaaacataca aacttatctt aggcaaattg
    24541 gatatggcaa ttatgatgtt tcaggtggta tctcaaactt ttggctagaa tcttcattaa
    24601 aaatatcacc tattgaacag gtagaattac ttgaaagttt ttatacaaat aagtttaaat
    24661 ttgaagataa aaatatagaa acagtaaaag attcattgtt aatatcaaaa aaggatgggg
    24721 tatcactttt tggtaaaaca ggcactgcca atataaatgg aaaagatgta aatggttggt
    24781 ttataggtta tgtggaaaaa aatgaaaata cttatttctt tgctacaaat attcaaagca
    24841 aagattattc taatggtagt tcagcatcta agataacatt atccatatta aatgacaaaa
    24901 aaatctataa tccttaatat atttactgta cattctaaaa aattcacata attttcatat
    24961 taattatcaa ttaaattcat atacaaggct tattatataa acatagaaga tagtaaaact
    25021 agcttaaaaa cataatataa taccctatac aaatagtggc aactctccct cacatcctca
    25081 attgttgcca ctatttaatt ttttgtatga agttaaatat attttcatca tttcaacaat
    25141 ttgggtgcaa tacaatctct attttgaaac aacctcttta attgttttag agtttatgaa
    25201 ttatttctca tactttaaaa agattgaatt actcttgata atcttctttt gtagtcatta
    25261 catatcacct actactcaac acatattctt tgacctattt ttacatcctt gtttatatcc
    25321 aaaatattta ccttcttacc atctggaaac aataccattg tcaaagtaga ctttcctaat
    25381 tcatgtattc tctttaaatc aacattaaca agaacgtctc cctgtttaac catatctcct
    25441 tgtttaacag caacatcaaa gccatctcca tttaatgcaa ctgtatcaat tccaacatga
    25501 attaatactt ctccattagt tcctttaatc ccaaatgcat gtccacttga aaccactgtt
    25561 tctaatttac ctgaaatagg agaaacaatt tttccatcta taatatcaat agcaaaacca
    25621 tcacctaaca tttttttaga aaatgtttca tctggtacat tttctaatgc aacaattttc
    25681 cccttagctg gagacacaaa gttttcatta ttttcattaa acactaattc ttcgtcttca
    25741 tcttcattta tagcttcttt aggcactcca aataaacatg ttacaataaa gcagaatgca
    25801 accacaaata ttgatactaa taagtatgtg attaaattat atccatcata gatatacatt
    25861 aaataagaag gtaaaactgc taatccatat gaattagatt gaatatgtaa aattgataat
    25921 attgctgctc ctaaacctga agatgcacac ataataatca aaggctttaa attatatcga
    25981 agctgaatcc caaataaaac aggctcactt ataccaaaaa gttgagatag cattgctcca
    26041 accgcagttt gtttaacttg attattttta gattttttca taaatgctag acatgttcca
    26101 atattcgcaa atccatacat tgcacaaaga gtaataaggg cattaaatcc tgtatttgct
    26161 aatagtgatg tttcaatcat tacataagta tgatgtaagc cagtaataac agctaatgga
    26221 tatgtaaatc caataataaa tcctccaatt cctaaaggca aatcaatcaa taagctgatg
    26281 atatcaacca tttttaattc tattgtatgc attatagggc ctacacctaa caaaataact
    26341 aacattgtta ttagcataac aaaaaatggt gtgaaaataa ggtctaatac attaggcata
    26401 tgtttacgga accatttttc aagattagct ccaataaatg ctgtaacaat agctgttaaa
    26461 acacttcctt gacaacctac aataggaata aatccaaatg ccataattgc ttcaatttca
    26521 tttgatgggt cagcaacaga atatgcatta ggaagtattg gggaaactaa cataagtcca
    26581 ataacaagtc caataacagg tgttcctcca aatactttaa atgctgacca tacaataatt
    26641 gctggtaaaa aagcaaatgc tgtttctgta agaaccgaaa caagtgtctg aatatacaat
    26701 ggaatatttg cagaagacat tccaaataat ccaagtacat tatcattaaa caaacaaccc
    26761 tttaatccca agaataatcc tgttgctgca ataactggaa taataggaac aaatatatct
    26821 gctagagttc tcataacttt cttaaatcca gtttcattat ttttaactaa ttcatcttgt
    26881 tctttttttg ataaagtttt taatcccatt ttttcaactt ctgcataaac tttattaact
    26941 attcctgttc ctaaaataat ttgatactgt ccagaagtaa agaaaacccc tttaacctca
    27001 tcaacttttt caactttctt atcattaata atttctctat ctttaaccat cactcttaat
    27061 cttgtggcac aatgtgtaat agaaataata ttatcttcac caataatttt aataagctca
    27121 tttgctattt tattatattt attcattttt ctacctcact ttcaataata ctgcatgaaa
    27181 tggtttcaaa cgcactgttt tatttaatag atttatatca tctaaatttt ggaatacaat
    27241 atcatatttt tcttctactc ttatttctac aggtttatca gaaaaattat aataacaatc
    27301 aataactacc aaatctaatt gccttctata cgcaataata tcatcacttt ctatatcaat
    27361 aggttctatt gaaccataaa tcaaacaatc agaatactca ctatcttgtc tcaactttat
    27421 catcttttta taaaattcta aaatactctc tgaattgtta atctgactct gtgcattaat
    27481 atctttataa ttttcaataa cctttaacca tggtgttgta tctgaaaaac ctgcattttc
    27541 tttatctgcc catggaaatg gcgttcttgc attatctcgg cttcttaaat tcacaaattc
    27601 taacgcttct tcttctgagt aactttcatc tattgaacga tagtattggt caatgctaga
    27661 taaatcatta aaatcattta tggtatctct tttaaaattt gtcattccta attcctgtcc
    27721 ctgataaata aatggggttc ctcttaaaaa gaaatacatt gctcccaaca tttttactgc
    27781 atcatcattc ctttcgtatt gcaaaagata ctttgttgta gctcttggtt ggtcatgatt
    27841 ttcaataaaa ttagctgccc atccatgttc ctgaacatac atttgactat ctaaaatgca
    27901 ttttcttaaa tctggaattg tccatgaaat tcttttaaac cactcactac cagaagcaac
    27961 atctaagtca gcatgtttaa agtcaaagac cattgaaaag aaaccatctt ctccaataaa
    28021 atcacctagc tggtcatagc taatacctgc tgcttcagca acagtcatac aatcatattt
    28081 tttaaacgta ttttctttta attcataaag cattttttct attccaggct gatttctaac
    28141 tgtttttgta catttaacaa gaccatcaac accatcactt tctaaacttt gaaaacttaa
    28201 attctttttg atgaatgtaa tagcatcaac tctaaatcct gccactccca tttgagacca
    28261 ggtattaatc atttggtaaa gttcacttct taatattgga ttttcccaat taaggtcagg
    28321 ttgtttttta ccaaaagaat gaaaataata ttcgtctcta ttctctacct tttcccaaac
    28381 acttccacca aaaacagacc tccagttatt tggtaaatcg tttccttttt taaaaatata
    28441 ataatcatga taaggacttt ctggattttt taatgcttct tgaaaccaag gatgttcatc
    28501 acttgtatga ttaagaacta aatctaatat aattttgatt cctctatctt tactttcttt
    28561 aattaactct tttaaatctt ccatacttcc aaattcactt gcaatatcca aataatcact
    28621 aatatcatac ccattatcgt ccataggtga tttaaaaatt ggacataacc acaatgatgt
    28681 aatacctaaa ttttttaaat aatctaaacg agaaataatt ccctgtaaat ctccaattcc
    28741 atcattatta ctatcttgaa agcttcttgg ataaatttga taaacgattt ctttttgcca
    28801 ccatttcttt tccataaatt actccttttt atatgatatt tcttcttttt aattctttat
    28861 aaattccatt atcgaatatg tcctcacata tagatgtcgc tatatcttta agttgttgat
    28921 gactattttt cattgcaatt gtaacgtctg atgcttgaaa catgacaaca tcgttttgac
    28981 catcaccaaa acatatggtt tctttttgag ttactcctaa tctttcttgt aatctcttaa
    29041 ttgctttgcc cttatgaaaa tctttttgaa taatttcata atactgacta gaaatatctc
    29101 tctgtgctaa ttccatttta tcttgtagta tatttttcac ttcgtcaaat accttttcat
    29161 ttgaccataa acaaatttta tgtatatctt gtgacttata ctcttcaatg ttattttcat
    29221 atgttatttt ttcttggata tgttgtttat ttatacaaga attagttcct ttcaactgat
    29281 tcattgtttc aaatatttct ttggcttttt gattcatgaa aactttttcc tgactctcaa
    29341 tcgaaaaagc aacttctctc ttttttaata aacaaacaac ttcctttatc aatctttgat
    29401 taaaagattg attataaagt aattcaccat gatattgaat gtaattacct cctcctgcaa
    29461 tatatccatc aactcctaat gataaaacat catcttgtat tgtacccata cttcttccag
    29521 tacaaataac aacactgcaa tgattctttt gacataaacg tatagcatgc tttgcagatt
    29581 ctgggattcc atatacctca tctctaagcg taccatctat atcaagtatt aataatttgt
    29641 acaatttcat cttcctttct tactatcaaa atcataatag cattcaaaaa aaaagatatc
    29701 aatattttga tatcttttaa aaaatatgtt catttttagc acaaattttc attttcgggg
    29761 aatatgttca ctttctaaat acatcttgta tttaatataa agcagttcaa ttaaaataaa
    29821 ataaggtgtt gttacatcgt agtccagttg tttatctaca gaaatagata tagattgaat
    29881 atacaggttt tcatcacata atcttgctaa aggattactt atcatttttg taatagaaac
    29941 catataaatt cctttcattc tcatttcttt agcaaaatca ataattgtag atgcatctcc
    30001 attcaatgaa ataaagaaaa tcatatcatc tgtttttata aaatgattaa gtgcctgaat
    30061 catatcataa ccataaacat catatataat tttccctgtt ggtaagaaaa tccttttcat
    30121 ctctttagca actctttcct gagaataacc ttctccaaag acgattatac gatttgcctt
    30181 tttcattctt tcaaacataa tcgaacaatc cttcttctct atatcatcta tcaccttatt
    30241 ataacaatcc attaattggt gtttactttg atttttatat tctacttctg tttcatttaa
    30301 gcgtataata actcttaatt cactatatcc aggtaattgt agtttttgag caaaacgaga
    30361 aagtgcactt gtagatatat ggtatttgtc tgcaaattca tctatagaaa gtttaataca
    30421 atcttcttta tgattaagaa tacactcaca gatatactta tcatttgctg taaatgaatt
    30481 ataatattta ttgaaaagtc cttcaatttt cattcttttc tccttctata ctctatgtaa
    30541 ttcatatgaa gcaaatctaa tagagcataa aatgctccta cgacttcata agatatagct
    30601 tgtaatgtat caagtttttg cgtttcaaca tacagattat actcacaaag tgttgcaatt
    30661 gtattattat caagcctagt taaagaaatc gtatgtatat gattgttgat aaattttgca
    30721 atttcaattc ctgcttttgt ttctccagac aaagaaatga taataaataa atcatttttt
    30781 tgaaatgatt ctctcataaa ttcaatttca cctatatcaa ataagtcaat aacacattta
    30841 cctactgaaa gaaatattct ctttatttct tgagctaaac ttttctgttc attacctgtc
    30901 ccataaatat aaattgtttc tgcatcatat attattttac aaatatcttg aaatgatatt
    30961 ttttgtaatt cattcattaa tagtcgataa ttctcgcaaa catcatgaaa attattatca
    31021 ttattaacaa attctagttg attattttta agtaaatact ttaaatcaga gaatgaatct
    31081 aatccaattt ttctacaaag ccttaataaa gtagctctag aaacattaca ttcatttgca
    31141 attttttcac acgaaaaatt acggtattct ctttgacaaa tcaatatttg tttaataata
    31201 attttatcat tttcatttaa attatcataa ttttggttaa ctaacgattc taatctcatt
    31261 ttttccactc cctaaatatt attttaatat acattagttg ctttttctag ggaagagttt
    31321 taaataataa ggataaaata atcatttgat tttattttta ttaaaataaa aataacctgc
    31381 taaaagcagg caccaaaaag tacttatcct ttcgaacatg tactttagat attgctttct
    31441 tcggaagctt catctcttca tactctaaaa tatagttttt tctaactcaa aagtattttc
    31501 catggtagaa attactttaa ttcatctgcc atttactttt tatcttattt aataattact
    31561 attacttgaa tatttacttc tttaagtaaa tttcatagtt aacaaagcta aaactattat
    31621 tatagatgtt aaaatacaaa attgtaagta ttgttataaa tatgcttaca gctacaaata
    31681 tacatgatat attaaaaaga agctgtaaat tattatcata catacaagca actatgcctc
    31741 tattaatcca tgttaatttt tattatttaa tacaaggagt tccatgagac atacatatcc
    31801 attcatattt taaattatcc aattctctta tagatttcac catcttttta taatcccaat
    31861 tccatggatt aggataagga actatatttc cattcttatt tttgactaaa tcacctgcaa
    31921 ataatacagc ttcaaaaatc atgcagacat gccctggagt atgaccagga gtatggataa
    31981 tttttatatt cccaatctgc atattctctc cataaggttc aacatcctta atgagccttc
    32041 tggaaattgc ctttccaata aacttcttaa acccaggtct atccttctct cctataataa
    32101 aaggtatatc ctctacatga gcccatactt ttgctcctgt tttttctttc aataatttaa
    32161 tattagatat atggtcaaca tcatgatgag ttaataaaat atgcttaata tctgtaagtt
    32221 taatgccaag tgtttttaat tctttaatta tatttttccc cataaaagga agacctgtgt
    32281 ctataagaat aatttcttta tcaaacacaa taaaacaatt tgagccacga gtactatcta
    32341 acattaatac attttctttt atcttcataa ataaattccc cttatttggt attttaccta
    32401 tataattaat taataaagtt ataaatagtt ataatacttg atattaattt tattttttat
    32461 taaagtatac tataggtata caagtattat atttacataa gtataccatc agtatacttt
    32521 tttatcaata gaaaggaata atttatatgt cagaattatc aaaaagagat aaagaaaaaa
    32581 tacaaagaga aaatgagatt attgataaag cagaaaaatt attttgtctt aatggatttg
    32641 ataatacaac tatgaatgaa ttagcaaaag aagttgaata tactaaacgc accatataca
    32701 agtacttttc atgtaaagaa gatttattct ttgctgttgt cttaagagga tataaaagac
    32761 tttgggataa tgttaaaata gaaagtgcaa aaggcaaaac agggtttgaa aaaataaaac
    32821 tttcatactt tgcttttcat aaattttact ctgtagaacc ttctctatta tgccttatgg
    32881 gaatgattgg tattgtaaac tctgaaaaat cggatactga tatgctgttt aaagaaaagt
    32941 ttttttcttt taataaattt atgtttgatg aaatacaagg aatgtttgaa attggaaaaa
    33001 atgatagaag tattaggcat gatattgaaa tacctactct tatgtattca tcaatattta
    33061 cacttacagg attttttaat ttactatctg taacaggaaa atcatacctg aacaacttta
    33121 atatagatga ggaaaaattt attgaaacaa ctcttgctct tttaatagat tcaattaaag
    33181 cataaaccta agtttataaa ttaaagttta tatacttaaa tgataatttt ttctatctct
    33241 aatataaaaa atattaaaca taaaactaat aacttagtta atggaataac taaattactg
    33301 aaaggattaa aagtaaatgg ctaaaatact tcttttagaa gatgatgata caattacatt
    33361 tggaataaaa acttcccttg aaaagaaaaa tcacactgta tgttgttata atacgattgc
    33421 tgaagctaaa aaaaattttg ataaaactat tgatttaatt ctgcttgatt taaatctacc
    33481 tgatggtatt ggatacgagt tttgccaata tgttaaaagt atagaagata ctccagtgat
    33541 atttttgaca gtccgtgatg atgaaaaaga cattatacgt ggattagata tgggtgcaga
    33601 tgactatgtg gttaaaccgt ttttgctctc agtacttcag tccagaatta atgcagttct
    33661 tagaagaact cattcaaata ctaacaatac tattacatgt gaaaatataa gcttgaataa
    33721 ggttgaagtc aaagcatatt tagataatgt tgaagtacct ttgacagcag gagaatataa
    33781 acttcttcta agtcttatgg aaaataaaaa tagagctatg actcgtacaa agttactaga
    33841 aatgctctgg gatgtagatg gtaatttcgt aaatgataac actcttactg ttacaataaa
    33901 acgtcttaga gaaaaattaa aaaatccacc ttgtataaaa acgttaagag gcataggata
    33961 tagaatggag gacagctagt gaaaactcca agaaatatca acagtacagt tgtttttata
    34021 atattctgct taattgtaac ttttttattg agtgtaattc taacaactat aacttctttt
    34081 aatgaataca atgtactgtc taaggctctt ggtgcatcat atgagtacaa tcctaagtct
    34141 acagaaagta tactaaaatc actgaaaaat tctagtgata aggattttaa aacaggaaat
    34201 gaaattttat caaaacatgg atattctaaa agtacatttt ggagtaaaaa ctttttttat
    34261 tttctagtga tatcgtttgg tataatttca acaatggcta cagttatata tataatcaaa
    34321 catagaacaa ataagcaaaa actgagtaga ataaacaatc ttactcaata cttagaagaa
    34381 gtgaatttag gaaaagagtc tgtactttta cgatgtgaag atgaattttc tcaccttgaa
    34441 gatgagatat ataaaacagt tggggaactt cgttgttcaa aagaatttgc tttaaaagaa
    34501 agacaaactc tttcagataa tcttgcagat attgctcatc aacttaagac tccaattact
    34561 tctatgtcac ttatggcaca attactttca gaaaattgtc cagatgaaga aatagattat
    34621 attaacagac ttacaaatca aatctcaaga cttgagagac tagtttcatc tttacttaca
    34681 ttatcaaaat tggatgcaag tactttaata tttgaaagca aacttataga tgtacattct
    34741 cttcttactt atgcaattga gcctatagaa ggttctttaa gagaaaaaca tcagacattt
    34801 actatcgagg cttctccttc ggtagaattt gaaatcgata ttaattggac tttagaagct
    34861 cttttaaata ttcttaaaaa ttgtagtgag catatagaag atggtggata tatagttgct
    34921 tattatagtc aaaatcctct atatgttgag attatcatag aagataatgg taaggggttt
    34981 gctcaggaag aacttccata tatttttaat agattttatc gtggtaaaaa tgctagtaag
    35041 gacagtattg gtatagggct tgctctatca aagtctatta tagaacgtca aaatggtact
    35101 ctacatgcag aaaattgcca taatggtggt gcaagattca taattaaatt ttacacataa
    35161 aatgctggat tataggtaaa atacctataa tccagctata tctatattct atgttatcta
    35221 ttgttttagt aatatacttc tatttacatt taaggtttta ttaaacaaac aacttaacta
    35281 tccctatact tgtaagtagt cttaaatcga aacctttaaa taagttcaaa tagattttgt
    35341 ttatattgtt tcatttttta tagattctac tatattttca ttcttcaact gcttgtatcc
    35401 tgtcatatat gatgctatta caataaaaag tatcaatata gtaaaaccta ttattgtaga
    35461 tataggtgca aatggtaaat actctataaa atatatttca tttatacgta gaaaagcata
    35521 cactattcct atttgcacag gaatactaag tagtaatggt gtaattccta agaataaacc
    35581 ttccaaaata agcatctttt ttatgccttc tggagataat ccaacagaac gcaacatagc
    35641 aaactcttgt cgtctacttc taatatttcc tgacactgta gcaagtacat ttgataatcc
    35701 aatcatagcc aataaacctg taataaagcc tactattaaa ttcatggtct ttattccact
    35761 agccttttgt ttttcacttt ctaaaacatc ctcaatacta taatctcctg aaccatagtc
    35821 tttattataa atggactcta atttttctct tactctagga atgtcctcac gattatttac
    35881 tttaaatact cctatcagcc tatttgaacg taacctactt acttcatcat aatttttaga
    35941 tatttcctgt accatagaca ttggaactat ttgcattaat gtatactttg aactagtatc
    36001 tactatttta ggaagtgtgc ttgtaatagc tcccactttc atgttgtaag tataatcccc
    36061 tttatcttcg tcatatactt tttcatttaa tttaatgtta tctcctattg aaagatttaa
    36121 ataatctata tatactttat ttctacgtgt actacgatta atatcttcct ccttattata
    36181 tacaattgag gttggatttt ttgtattata aaataacttt gggtctacag aaatttgcct
    36241 acaatattct gtaaaactct tatcatcaag cccaattata tttgaaatta tacgaaactt
    36301 gccatcacgt tctataggag agtatttttt agatgaaact atacttttaa atcctccatt
    36361 tttcgcaagt tcttttgatg catctttttc agtcagccaa gtggaagcag acattttttg
    36421 ataatatagt gaacttttta caccttctgt attatctaat ttttcaatga aagcagactc
    36481 tataggttca ctattttcca aataaactgc tatatctctt tggtccttat aattatcact
    36541 tccataaaca gcttttgctc cttcttgatt tgcaattata tgcaaaaaac atgtaagtaa
    36601 taaaaaagat aatgttaaag atattgttgc agtacgataa gattttttac gagcacgtag
    36661 tgcgtttgat gcaagttctc cttctattcc aaatatcttt cctaatgaat atttatgcga
    36721 ctttttgatt ttaacactat ctccttgtcg tattgcttct ataggagata tctttgatac
    36781 ttttcgtgct ggtataagtg cagaaatcca gactgttact attgtaagta aaactgctgg
    36841 cagaaaagca ggaataccat aagtaaatac cacttctgga acatcagtat gataattaac
    36901 tgaattaaca taaactataa gcctattaca caataaccat cctaaaaata aacctattgg
    36961 taatggtata attgtcagta aaaagccttc aaacactaca gaccttttaa tttgttttgg
    37021 tgatgcacca acactagata atatccctaa ctgagtaagt ctagcatttg cagacagtga
    37081 aaacgcgttg taaatcacca ttacaaacac ggctactgta aaaattgcta ttgtaagata
    37141 cataatagga gttgaaaatt ttgatatact actcatagat gctttctgtt ctggtgaaaa
    37201 gactaacatc tttaaaagat aattactatt gtatttaaga ttgtattttc catattcatt
    37261 agtcttccat cccaatgatt tagcaagttt tggaagttcc ttatacgtgt ctcttatatt
    37321 tttaaatcgc aagtacacag ttatactatc attaggtttt atacttgttt tatcaagata
    37381 tccaagagct gtatatgcag gtattactga tgaagtagaa acatctacct ttcctactat
    37441 tgtcaatgta gcctctgaaa tttttttaaa actttcccct ttcgattttg gggctatggg
    37501 ttcaagaggc tttccattta agattctata tcctattggg agagtaattt tatcaccaat
    37561 ttttacactt ggattattct caaaatattg ttttgataat gcaatttcat tagcattatt
    37621 tggtcgacga ccctctatta tagtatcctt ttctggcata gaattccaat actctgatgt
    37681 agcatttcta taaattatat aatctctttt ctcatcatta attttgccta cataccattg
    37741 tccttttacc attacatcat caactgaaga aaaattttca attaatggta agtcacttcc
    37801 ataagtatag tcaaacaatt caccatgcca gttaccttct ttctcaattg aaagtcttat
    37861 aaaatctgtc cacatggtat acaacagtcc acacaaagaa gacatcatgg ttgtagtaag
    37921 taatatagct aacattatag ctatactact acgtttattg cgtcgtacaa agtctaaggt
    37981 gtattcttga agaatattca tttcttcacc accttttcag agacaatcac tccatcttcc
    38041 atagttacaa tacgatttgc ctctagtgct attttctcat catgagtaat aagaagtatt
    38101 gtctgattaa atcgtttatt tgataagttt aacaagtcta caatttcttc tgaatttttt
    38161 ctatcaagat taccagttgg ctcatctgct aataaaatag ctggtctata gattaaactt
    38221 ctagctatag ataccctttg ttgttgtcca cctgaaagtt gacttggaag atggtttaat
    38281 ctatcagata atcccaatat agatacaatc tcagagaatc tatcctcatc cacctttctt
    38341 ttatcaagta acatgggtaa taatatattt tttctaacat caagggtagg tataagatta
    38401 taaaattgat aaataagacc tacttttcta cgtctaaaaa ctgcaagagc ttcttccttt
    38461 aaacttgata tttctgtatc ttcaacataa atctttccag atgtaggtct atctactccc
    38521 ccaagcagat gtaacaatgt agatttgcca gaaccagatg ctcctacaat ggatacaaaa
    38581 tcaccttttt gaactgataa atttacatta ttaagggctg tcactctggt ttgatttgaa
    38641 ccatatattt ttgtgagatt ttcacatttt aatatttcca tatacaatca tctcctttat
    38701 ggttaaattt tagcaaccta aaatgacatt atagtgacat gaatacaaat ataaattact
    38761 attaaaaata ttgtttagtt tttgcacatt atttaaaatt ataatataaa acaaaaacta
    38821 tgcaatatat tttatttata cttttaatat attacatagt ctttaaaagg tattaacttt
    38881 aaatctatag gtattcaatt taataatcaa tagcaagtat tttatgtact aaaggagttt
    38941 tgctctatat agactcaatt tagtaaaatt atttaataaa tattacagac tataggtaaa
    39001 taatatttac aaataaaatt aagtttattc ccttacacta taatatttct taattatatt
    39061 aattgcaatt tcctttacct ttggccctgt aatttcttta ttggaatcat ctgatttaat
    39121 agcaaaataa taggtgtcac cttcacgctc tagcatacca acaaaccatg catccacacg
    39181 tttatttttt tcatcaaatc ctgttccagt ttttccatat acatttatgt ttttatcatt
    39241 tatatctatt ttcataatat ctcttaaaat attaatatgc tcttttttaa agtttgtatc
    39301 tccctcaaat atttttgcca ttgtttgcac ttgttctttt ggagatattt gtaatgaaga
    39361 ttctaaccaa aatccattta aatgtccctt tccatttttt aaatcgcctt cccattcgct
    39421 aatatcgcaa ttcccatact ttaaatcatc taaaatgttt tggacagatt tagcatcaac
    39481 tttatctatc aattttttgt aataccaaac acaagactcc ttaaatgcct cttctaaact
    39541 aagattttta ttccaatttt tatttggata ctctgtacca tcatatccca taactgattc
    39601 ttttgagttt attacccctt tttctaaacc aattaaagtt gaaactattt taaaagtaga
    39661 acatggtgac cttcttgttt caattaattc tttgttatat atattatatt ctttattttt
    39721 agtattataa aaaatagctc ctccactaat accttcaaaa caatcactat agtcaaccat
    39781 attaattttt tcttttttgt ttttatcatt gttttcaatt ttggatttat ttaattcaga
    39841 cttatttaat tcagatttta tataattctt atcagttttt tgatttatat cgttatgttt
    39901 tttccctaca taatacatta ccataactac accaaccaat aagatagcta tccaaataaa
    39961 attctttttt cttttcataa tttatatcat ctcccatatt taaatttata acctactatt
    40021 aaaatagtag acattatttg taatatactc caatctaggt tctacttata agaaacaaga
    40081 ctaaatgaat agctgtatct cttatatttt cttcacctag tacaattatg ttgattaaac
    40141 ctattgcgaa gataattagg taactattaa taacatcctg tcctcctttt aatttgtgat
    40201 ataataattg attccacatt taaaacttac tattgtaata tttaaatatt acaatagtaa
    40261 gttttaaatg tcaagttagt ttaggaaagt tattttaatt gtataattgt tattacattt
    40321 ataaaatatg gcatgtttaa aattattttg ctattgggag gattaa
//
LOCUS       DAMJVG010000032        40080 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.032, whole genome shotgun sequence.
ACCESSION   DAMJVG010000032 DAMJVG010000000
VERSION     DAMJVG010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 40080)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40080)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40080
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.032"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            280..735
                     /gene="smpB"
                     /locus_tag="PC512_001787"
     CDS             280..735
                     /gene="smpB"
                     /locus_tag="PC512_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HDF2441533.1"
                     /translation="MAGKKILATNKRARHEYFIEETYECGIELKGTEVKSIRQGKVNL
                     SDGFASVDNSEVFLKQVHISPYEQGNIFNVDSLRVRKLLLHKHEIRKLIGATTIKGYS
                     LIPLSLYLKNGKVKVEIALAKGKKLYDKRQDMAKKDAQRRIEREMTGKY"
     gene            893..1242
                     /gene="ssrA"
                     /locus_tag="PC512_001788"
     tmRNA           893..1242
                     /gene="ssrA"
                     /locus_tag="PC512_001788"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            1357..3384
                     /locus_tag="PC512_001789"
     CDS             1357..3384
                     /locus_tag="PC512_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HDF2441534.1"
                     /translation="MSIDNNFNHVAFLWNIAESLRGTYKEEDYRKVMLPLIVIRRFDC
                     LLDDYDREIIKSVYEEYDFLPEEERDELVIVDLKENHDINLQFYNVSDFTWKKLLDDS
                     ENIKSNFEEYLNGFSNNVKEIIGKFKFKDEINQLDKKDKLYAVLSKMYEVDLHINSVS
                     NNKMGYIYEEMLRRFTENSAAGEQYTPREVIRLCMEILFMGKENFLTEEGKVISIADF
                     CCGTGGMLSIAEDYVEKINPSAIVNVYGQELLDESFAICQADMLMKGQNPDNIRLGNT
                     LTQDRFNGEKIRFLISNPPFGVTWKDEEKKVKEEADLGFDGRFGAGTPRVSDGSLLFL
                     QNMISKMYDDEEGSRIAIIFNGSPLFTGDAGSGESNIRKWIIENDLLEGIIALPTDMF
                     YNTGIATYIWVLTNKKEAKRKGKIQLVNASEYYQLMRKSLGNKRKEISLEQIEQIKEI
                     YEKFEESENSKIFDNEDFGYRKVTIERPLKLSFKVNEEAIENVKNTTQFINLAVSKKK
                     DIEVKEKEEAEGKIKQDKLIKLLESFDNTLEYMDRDKFIKDLKAKSKEFDIQLSAGLI
                     KAIVNTIGVRNEDAEVCKDSKGNIESDSSLKDTESIGLKDDVYEYFEKEVKPHVNDAY
                     IDESSINNIGYEIPFTRHFYKYEELRSFAEIMKEVESLESEIALKIRKVLG"
     gene            3384..4775
                     /locus_tag="PC512_001790"
     CDS             3384..4775
                     /locus_tag="PC512_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010233411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HDF2441535.1"
                     /translation="MGYRYRSDDELKDSGVEWLGKIPKDWEVRQLKRVLSDRKENNEP
                     IKTSNILSLTIEKGVIPYSEKGTGGNKAKEDLTQYKLVYPNDIVLNSMNVIVGAVGLS
                     KYFGCASPAYYMLYKINANDDIRFYNYIFKSKLFQDSLKGLGNGIMMKQSETSGKLNT
                     IRMRIPMEKLSSVKIPIAFNLDQEKIANFLDEKTSQFDSIISKKEKLIERLEEAKKSL
                     ISEVVTGKVKVVKTDDGYELIKRSSEEMKDSGVEWLGEIPKEWDIKRLRFLGKLQNGI
                     SKSSDSFGYGYPFVSYSNVYRNIELPHIVEGLVNSTEEERKIYSVEEGDVFFTRTSET
                     VEEIGFASTCMKTIDNSTFAGFLIRFRPNDKRLYKGFSKYYFRCDLNRKYFVKEMNLV
                     TRASLSQNLLNNLSVVLPKYEEQVEIYNALELKVSYINLSINKLKYQIEKLKEAKQSL
                     ISEAVTGKIEILD"
     gene            4837..6108
                     /locus_tag="PC512_001791"
     CDS             4837..6108
                     /locus_tag="PC512_001791"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441536.1"
                     /translation="MDKNIFQININTDVLIRLRNQINEEYYISYRKEFYDKNNKKHRA
                     WDKICAIMDRLDDTVDYLNKLKLNTGKYRRSAFDFFEFMNQASVVMDCITHLAKIFEV
                     PYEEVETSTEIFNELGKEGKGTDKKYFEYLRSLCSVHPMETSRHKIYQENSFECSPYV
                     VWNDKSIWTNDASDLYAVVYTSKDNDSFKRIHIYMNQIFEYVKRRVNFIENIIEHIEK
                     YQQEIIEIFRNTPIKKEEDFESYIDYLRNLKKEIEIRYGNDSFHELNYLIELFDLPLS
                     NPDNEEKMNLYKNALKYAIKFEHNSIQNMTNEGYKNNGILYPQVNITTTLLEELISLN
                     SGSEERRKYRYAIEKTSYLSYDSCWSDREWAYDQIDDMMPFLERYVTFDKAQSDFEHY
                     VLVKLALYLECLENECLINKNVPNDKKFRIK"
     gene            6143..9124
                     /locus_tag="PC512_001792"
     CDS             6143..9124
                     /locus_tag="PC512_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HDF2441537.1"
                     /translation="MLPKEKHLEESIENHLVSIGYEQGHSQEFDLENCLFVDDLFRFL
                     ENTQKELLDEFKYNRGSNYKKAFIDLLNSNIKRRGLISVLRNGVEDIMMNGKFQLFYN
                     KPNLTTNKTAYENYKQNIFKITRQLKYSSKHNNTLDIVLSLNGFPVIVMELKNQFTNQ
                     NVYNAIKQFKKDRNPKETLFGFNQRVLVYFAVDTDEVYMTTELKGDKTFFLPFNKGNN
                     RGKGNPVVEGKEKTSYLWEEILTKDSLLDIIKRFYFIQEDDKGNQRAIFPRFHQLDAV
                     RKIVEDLKINKVGKNYLIQHSAGSGKTNTIAWTSHRLSSLHDEENNAIFDSIIVVTDR
                     KVLDKQLQNAIYQLEHKNGLVVKIDEDKNSSDLADAIVNRAKIIITTIQKFQYALPKI
                     EQLDKRRYAVIIDEAHSSTSGENMNALKETLAGKTLEEAKVIDAENEKNEKSSIDKMN
                     ELIEKRTNLGNISFFAFTATPKNKTMQVFGRIGEDGLPHEFHLYSMKQAIEEGFILDV
                     LKNFMPISVYYKVGKKIIDNPEFDKGEAKRAINKFVSLNEHNIRQKVETIVDDFVDNR
                     SMWLEGKAKGMIVTASRLHAVRYKLAIDQYIKEKGYDMKALVAFSGTVKDGDDEYTEV
                     GMNKEVAPDITDSNLPNIFDKNEFKLLIVAEKYQTGFDQPKLCAMYVDKKLDGVKTVQ
                     TLSRLNRTYPNKQTFILDFQNSVEDIQDAYKPYFEMTNIDKVTDPNVVNDLWYQLHEY
                     AVYTDEEVNDFTVLFYKEKRTSSQDAKMNNLIDKAVERYCYLEEDDEKKSDEFKKKCQ
                     KYITFYNFLIQIYPIKNLNLLRLQVYLVALLKKLPKKSKQRIDLDDMLSLDYYKLQKL
                     GLDDKKGTDISLYNGEGELVGISETATSRVSEADEEYLEDIIKKINDVFGVGLTEDDR
                     IMINTYEEMFKNDKDIMDIAKANSYEDLVSTFGKKYFKRGIVKTKNRNDRLVKEILTN
                     NNLQNYMIHYLAEKIYEEANR"
     gene            complement(9183..9353)
                     /locus_tag="PC512_001793"
     CDS             complement(9183..9353)
                     /locus_tag="PC512_001793"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441538.1"
                     /translation="MNNDKPFIEFEEEVDFILTECKKEGVSIDRDTIELILDLDLKFL
                     ELKGIATPLEDE"
     gene            9634..9969
                     /locus_tag="PC512_001794"
     CDS             9634..9969
                     /locus_tag="PC512_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441539.1"
                     /translation="MIKLWKKEDLNLLLEYPKEVVENVDNVINILDENYGCNRKLTDD
                     GGYVCIIEDIKEVENLKSNILKGLVEEFSDVIYEDEVNTYNSTLYLLSSDYSVTVISK
                     NEETEYLLK"
     gene            10033..10491
                     /locus_tag="PC512_001795"
                     /pseudo
     CDS             10033..10491
                     /locus_tag="PC512_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427593.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="JAB domain-containing protein"
     gene            10631..10924
                     /locus_tag="PC512_001796"
     CDS             10631..10924
                     /locus_tag="PC512_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441540.1"
                     /translation="MFKKENRYMTKEIAENLPIEIAILLWNLIDDLTTEKDYLQLFEI
                     NPIGLGVVEIVHKQEVPEYEARIYIQNDKIKDKLKIYVIDNVEYRTMMFSNEY"
     gene            10951..11547
                     /locus_tag="PC512_001797"
     CDS             10951..11547
                     /locus_tag="PC512_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441541.1"
                     /translation="MINNKSEIINKLFFNELKELIDKYNNIDDKTVDVIEKIFTCIED
                     EEIKNYLIRDNCKLQELVNTYNKLEDLNIDEAIFFAWYNLTINTISIDKASEYYDDLT
                     TSNYIEVENHIIYTNERDLRKYAEDELETMLSMEHHIDRLLHKDMLIDMWLNNTSKEE
                     VIEEILMSDDIEDILNLSPEYAFTLANGIEYRYSEKEE"
     gene            11700..11969
                     /locus_tag="PC512_001798"
     CDS             11700..11969
                     /locus_tag="PC512_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003487728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mor transcription activator family protein"
                     /protein_id="HDF2441542.1"
                     /translation="MTNNNNNCDYKGIYADMVEVLGEEIVIKLHKYYRGQQITFPMKL
                     YSIEYVERYIVKNYRTKTIKEMCRELGYTEGWIKQLINKNRLNSK"
     gene            11995..12237
                     /locus_tag="PC512_001799"
     CDS             11995..12237
                     /locus_tag="PC512_001799"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441543.1"
                     /translation="MILTVLAILMGTGIFFLINSMLDITYFGCGPIGFLWFGCFIVSY
                     AILTSLGGIVLGLLKWIVIGLIILFVIGLIANKIND"
     gene            12443..13576
                     /locus_tag="PC512_001800"
     CDS             12443..13576
                     /locus_tag="PC512_001800"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012938.1,HMM:NF016983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosome-binding GTPase"
                     /protein_id="HDF2441544.1"
                     /translation="MQDFDFISETIKKFQSDLENMDKVNILVVGKTGVGKSTLINNIF
                     REELAETGIGRPVTQHLKKISKEGLPINLYDTKGLELEEDVQETIKKEILDEIENCNR
                     NSLERNDKSELMHVCWYCINTSVARCEETDIKWINELSEKIPVIVVLTQGFPRKKARE
                     LKSSIDDLNLNCKNVIPVLAEQLVEEEDEIVIKSYGLDKLVEVTYQVIPKEVKKAFVN
                     VQKVDIKKKVEESRKWVLGYVGGSGAIGFSPIPFSDAPLLATAQVAMISHITVIFGLQ
                     VDKALLTAIVSSIGGVTSATLLGKTLVSNILKFIPGAGTIAGGAISGSVAALTTTALG
                     MAYISVLEYILNENMKGNEVNNTEIAEKMKDAYKDQLGMLSKK"
     gene            14340..14585
                     /locus_tag="PC512_001801"
     CDS             14340..14585
                     /locus_tag="PC512_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441545.1"
                     /translation="MRSVTVEDGDERFAIEKIYIKSLQRYEVRICLYRDCRDRINKLI
                     PRPVDLTMDKFVALILVGLKAGVLDDDFKQELIKGLA"
     gene            14933..16294
                     /locus_tag="PC512_001802"
     CDS             14933..16294
                     /locus_tag="PC512_001802"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441546.1"
                     /translation="MKGNINKKDIDLSKITFDKFLEDEGLQNRERDYLYVDDYDNTLD
                     TQEFKLHIIEENTDNTYIDKDKYWYLDLDDSLFEYEEDEDTIAKTLYSLIDIRIKFLK
                     HVEYRKYINLGVIDEEYFDEIKSFLKFYIVAKTKKNELGNSNLKQMAIDIFDKERFED
                     DISDDDMENISEWIGEDQNFKMFYDKVCRDLSNSTQDKEILKLAGIRNNKVKHYKGRK
                     ISRKCKLELKSLTKMWEYETKLTHDANKAHKKIKSNMLEKMTDKNYKNIYEYLNNEII
                     NSNEEYKNIYFYSLELKLANELRKCTLKNLNKIKDIENQVKFISYTIAYIHIVPVLTI
                     REKLSDKLFNILSTNEGKDIEKFTKEVSLIMRIINIECLELLNIVSKNNYYKNFSEKE
                     LEEFKSIYNINNGRKSFENKYKIKVDYNIDDVRKYGEVIKAINIESKKKIVDRIKKKR
                     KSN"
     gene            16484..16801
                     /locus_tag="PC512_001803"
     CDS             16484..16801
                     /locus_tag="PC512_001803"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441547.1"
                     /translation="MTNFKSVKVELILLIECEEGNRNELEGMIDEGVLNEKEYSLTIL
                     GSTEYEDNARAIYILMNTGGSYEKNLQRLSRLHLKIENLLKDTNVKYRGISLVPNIVK
                     WDK"
     gene            16813..18576
                     /locus_tag="PC512_001804"
     CDS             16813..18576
                     /locus_tag="PC512_001804"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441548.1"
                     /translation="MSKAINREELIKLYEEIGLNVLDNNTVMNSSNKKICNFLVNIIE
                     QRVIDGKMYLCINAMGINGELLSEVILDSNTINRTTWVIENWGFKYSIDKKYINDFIE
                     LIQHLCMNIKTKYIYDHTGWIYQDNKWIYLHGGGVIGGSDVQVELDESIDNYILPDKI
                     SDINKACEMSLKLVDLIEDDKGIIFSSLVYLSPLIEIISRKIKPPENIVWTYGKTGSR
                     KTAVSKVVLSHFGDFNKKIPATFNDTITAIELKANKLKDSLYLCDDFAPKQDFRDKKI
                     QDSKAESIIRMYGDRVGKGRSSNKLDIKDAKRPRGMILITGEDVICGESSNARLLSIE
                     LNRSSVDLNILTELQNNSHLLGEAMRGYIEWLLSEMGNIDELSNILLYNFKSYRDEIR
                     EQYKDDIHGRTIESSAWILVGFSCMLNYIRDKGVIDKYEDDEYMDRAIKVVERLIEEQ
                     IKLISRNSPIDIFLNTLKESINSKSIRIATLNDQNQVIEDKLEYICGYKDKEYYYFYT
                     DKVYSFIEFENKKRGIHLGISQRQLVKQLRDSGIVKVDSNNDSPKKTIHTKDASDSTG
                     YTTIRPRMLQIERSIIENFQI"
     gene            18639..18794
                     /locus_tag="PC512_001805"
     CDS             18639..18794
                     /locus_tag="PC512_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441549.1"
                     /translation="MTETYKISIGRKDLYSKDYKVVERTDYEKRHTVNISRSLVDILS
                     ILVKEDR"
     gene            18881..20446
                     /locus_tag="PC512_001806"
     CDS             18881..20446
                     /locus_tag="PC512_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDF2441550.1"
                     /translation="MTGKKAVVYARFSSDNQRDESIDAQLRAINEYADKNNIKIVNQF
                     IDRAKSATSDKRPEFQNMIKFCEADTTGISMVIVHKLDRFSRDKYDSAMYKQKLKVKG
                     IRVVSVLENLDNSPESLILESVIEGMAQYYSANLAREVAKGQKENALKALHNGGDAPL
                     GYDVAHDKTYTVNEEEAQAVKIIFDRYIKGYSYSKIIDELNILGYKTKRGNKFGKNSL
                     HGILNNEKYTGVYVFNKTQRKGVDGKRNGHKQKSEEEIIKIEGGMPQIIDKGVFKQAQ
                     DMIQKRKKTPGAHKATTTYLLTGLIKCGECGHAFQGNKRKDSYGNEYVSYRCGCRKQK
                     RECNNREIKRDYLEEFILQELEKNILNDEAIPILSKALNEKLNDKNESNAELLKNLEQ
                     KLDKVNKEISNILNAIMNGIVNSMLKDKLDELEQVKFNLDLKMNELKIENKVVDGVGV
                     TEDQIRGMFSRFKEFVLERNIPECKKFIGDYIKEVIVYKDHIEVIFNVVFCFVDNDIT
                     HDLHIITERGKIT"
     gene            20592..21884
                     /locus_tag="PC512_001807"
     CDS             20592..21884
                     /locus_tag="PC512_001807"
                     /inference="COORDINATES: protein motif:HMM:NF014177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HDF2441551.1"
                     /translation="MADIFTVLNYQGSKKRLLDFIYENTQEYIDSDKAFLDICSGTSA
                     VAYNMKRHFTVYTNDSENYAYQISNSIVKNNERYNFSQSDEMIIREKYNINLQRLNNI
                     FNDMVNQEDMLLEQEDADGLIELYSNCPCIWKNNVDIEIEGNTIQSIYDLRKCKRDIP
                     NVLFTLYYSSSYFGIKQSMEIDSIRYAIEFIESEITKSILFTSLFFAMKECVFAKDGH
                     MAQPLNMETGKKRMLRLKARSIYDIFIDKLKEFNTEEFVLSQKENKCFNKDFRTLLET
                     EESIKDEVGFIYIDPPYTDMQYSRYYHILNTVVLYDYPEISLSRGTISKGIYREGRYQ
                     SPLSQRKHALNEIDFLFSFCKENKINVALSYAYPIDTEKQATNRYTASIDDLINVAKK
                     HFGDNVKVVHEEYSHANNRNSDKKNVLEYLIMGIHNKE"
     gene            21887..23506
                     /locus_tag="PC512_001808"
     CDS             21887..23506
                     /locus_tag="PC512_001808"
                     /inference="COORDINATES: protein motif:HMM:NF013704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HDF2441552.1"
                     /translation="MDKINKLKERIANIEATNKNDIYSSNLYWSQKPFNICDEIIEHL
                     SEDGDIIFDPFMGSGVTVIEALKKEYKRNAIGCDINDAPIFIVKTLLEKYNVPKIEKD
                     IKELNNKLSKLSTYYSTKCRECGEVVTISKTIFDKENRNAKCELKSIHYKCKECKNDF
                     KGEPNETEISKFFIDEELKNIDDFQFIANSRLAVGEGDTVRTIFSNRNLIVLDKILGH
                     IDEYKNSESYEPMKYILLSILHLSKITDTHSNSQWPLWIPKKDCVEKNVVELFIKNSK
                     KTIKALKLASKYLCENRENVELIKNLDRGKFKLIKDGVQNIEDDVIPNEFVDLIITDP
                     PYMGQVLYSEYMQLYKPFMDLEFELENEIVISSAPARDKGKVLYFDMMNSAFENISRV
                     LKVGKYMCMYFHDSNLDVWDNIIDIMTNNNLKYMGQIHVSKNKNTLKNILSPKKSLNG
                     DCIIFFKKDLNINYDINEVDNIEDKINNIAQAIIDIKGYASTPELYDNGALEYIISNG
                     KLKEISKKYKDLTSIFEQRFNWDKERGVWTV"
     gene            complement(23631..24782)
                     /locus_tag="PC512_001809"
     CDS             complement(23631..24782)
                     /locus_tag="PC512_001809"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441553.1"
                     /translation="MKKLTIRLKDDFHKDLLDLVAFKNDSINSYVINLIKNDLSKNTN
                     LLRSYDNMIRDNITNVLITQKINELKAIQDGIFKEYKVNDILSNSKIYEVMTANSLNH
                     ILIPGHSGSRDAKDEFGNEFEYKHFKKSSSNHSWTFNDFSDTSIAKLKKAKAVIFAHI
                     NDVDFPYPGKLDWYYSIPGDIMCEYLLKYTQSIQNSRKMINVSPNQLESRLNASKIIP
                     SAQNGVYDKYLSAIYKASSELEELTGVKNLLTSNKFWELIVALELNHQVNPEQGGREG
                     AHDAYDSEGNPYEYKVSKNHAWNFQDISDNVLNKYYNDKAIILAVVDKENIEVEHIYS
                     TEPADVVPLLRKKLQEKINRCLEKGSPIRRLQVSLSKSDLTRVNAKKLY"
     gene            25288..25503
                     /locus_tag="PC512_001810"
     CDS             25288..25503
                     /locus_tag="PC512_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3791 domain-containing protein"
                     /protein_id="HDF2441554.1"
                     /translation="MDERKLEFSIFCIEALAEKLNIDSEGVYKLLKHDTDILDNYIIP
                     CYEALHSQSKGYIVEDLMQVLKEKGVI"
     gene            25503..25982
                     /locus_tag="PC512_001811"
     CDS             25503..25982
                     /locus_tag="PC512_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3990 domain-containing protein"
                     /protein_id="HDF2441555.1"
                     /translation="MIVYHGSYCVVKTPSITFSRDSLDFGKGFYVTSIKTQAINWTER
                     FKKRGKKAYLNSYSLDIDKLKENCKVKIFDSYNLEWLDFIIECRNMSDIYMKYDIIIG
                     GIADDKIYNTIELYQDNLIEKDEALKRLKYYKPNEQICITNQNVIDKYLKFRYEEEV"
     gene            25988..26218
                     /locus_tag="PC512_001812"
     CDS             25988..26218
                     /locus_tag="PC512_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441556.1"
                     /translation="MEANKTLLQILYKKIILEFSKQTGKSLEESMDYLYTSETYKLIS
                     EGVSDMHCKGHIYLAQELMLENGLMYHKGYPR"
     gene            complement(26334..27500)
                     /locus_tag="PC512_001813"
     CDS             complement(26334..27500)
                     /locus_tag="PC512_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDF2441557.1"
                     /translation="MATKRANGEGSIGKYKDGWRSRIMIGYNEDGKPLRKEFYGKTQK
                     EVKDKLDAYKKQYYLSSDISDDKITLEHWFYNWLFEYRIKDLKPKSFERYESIYRNYI
                     KDTDLGNVKLKYLRVSHIQKYYNRLLDSNKSIPTIRQINTKLKTCLSEAEKQGLIQRN
                     YCTMVNIPVEKKENKLEILTLEQQKSFIKAIDGHKLEVLFLLALGTGLRLGELLGLKW
                     FDIDFKKSNLTVKRTLQRTYFIDKTGNRELKVLEQGPKTSNSYRTVPIPKDVLNKLKE
                     HKVNQNTDILKAGELYINNNYVFCNELGIPIDDKRPLRNLKSILNSLNIEPIKFHGLR
                     KTYATRLFENDVPPKTVQVLMGHYDISITLNIYTQVMEDKKVEAVEKLDKIFSL"
     gene            complement(27490..28242)
                     /locus_tag="PC512_001814"
     CDS             complement(27490..28242)
                     /locus_tag="PC512_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HDF2441558.1"
                     /translation="MNKSYIPKYTHKFPTNIPHGDKKYTLTYIRRMISEFVYDMGNLE
                     NNPFTFPEVQTLLDGITVGGHKLSDQNQILNIKSSWDYVIKLSNKENLSLNKDTICSI
                     HKIVAKDEALIVGDFRNGNIGIAGTTQYECIEATLLNDLFVNDINIINKITNPLEKAI
                     IINLWLSYCQFFYDGNKRTARLTSNLILINNDIGVLSIPAKHKQEYNTLMLNFYETLE
                     ADEVIKFLLEKCITFFDGYNYKSYKELFKNGN"
     gene            complement(28334..28825)
                     /locus_tag="PC512_001815"
     CDS             complement(28334..28825)
                     /locus_tag="PC512_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2441559.1"
                     /translation="MMNNTIGEKIKQYRKSINMSRDELANKIGCSVHAIAKYEQNQRM
                     PSLDMIRKIATALSIAINKLIVEENDLDTLTNNNINLKVFDKELDLVIHILENYGYDI
                     KTDYKKKFEITDNADTIKPINLNFSDFKDFSKNLNWVINGLVENFIQENSNGLIEDED
                     EEY"
     gene            complement(28822..29020)
                     /locus_tag="PC512_001816"
                     /pseudo
     CDS             complement(28822..29020)
                     /locus_tag="PC512_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729178.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(29077..29838)
                     /locus_tag="PC512_001817"
     CDS             complement(29077..29838)
                     /locus_tag="PC512_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2441560.1"
                     /translation="MQIGKNLKKIRKQKELTQIQLAEISGISRNALINYENDKRIPSI
                     DTLSKLAKALKIEKTIFYFDIENEVMTNEDVLYLLQSLFPEEYYSFDEFLNAISNLME
                     DDIRITSSLLLGAWSDKDQYYKLGEKLELNENQVYNWILSDCISNTELDFSLHPDDIK
                     EIIKNDVLTKQSIDELLDIGLSEESIETIYDYFSDSTDNGSNIRLKKLISQKENITIK
                     NNDYFKLLQENNELKEKNEKLENTLKEIKKLLTKI"
     gene            29985..30185
                     /locus_tag="PC512_001818"
     CDS             29985..30185
                     /locus_tag="PC512_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2441561.1"
                     /translation="MGINLKIFRIKKGLKQQELADRVGISRYYLSNLETGKANNPSND
                     LMIKLSRALDTTVEELFFSKED"
     gene            30189..30503
                     /locus_tag="PC512_001819"
     CDS             30189..30503
                     /locus_tag="PC512_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441562.1"
                     /translation="MKENNNLEVLKTLQATLNIIVKNEEEAQEKKQGYKIIENAKRNK
                     AELITCKEASKLYPIGESKFRQLCHSKNKGFPCIWINNRVYIIKNKLDDWFIENANGI
                     KL"
     gene            30525..31268
                     /locus_tag="PC512_001820"
     CDS             30525..31268
                     /locus_tag="PC512_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441563.1"
                     /translation="MSNKGWIKLYRELLDKSIWKDIKPERKVILITLLLMASHKENHV
                     FIDNKKIKIKFGQFISSYSKIAERCGKGVSYQMVRSCLLVFKNAGFLTYETTNKYIVI
                     TIENWELYQENIENQQPNQQTINNQSTTIKNIKNENNIIYSEIISKFNSTCIELSKVK
                     KLTDTRKRRINSRIKEYDKETVLEVINIVSKTSFLNGNNNTGWKANFDWIMNSSNFTK
                     ILEGNYNSKEIVINKETGIYNPDDSQLKW"
     gene            complement(31974..33887)
                     /locus_tag="PC512_001821"
     CDS             complement(31974..33887)
                     /locus_tag="PC512_001821"
                     /inference="COORDINATES: protein motif:HMM:NF020926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1998 domain-containing protein"
                     /protein_id="HDF2441564.1"
                     /translation="MSIKLDDKTHNLRINQATSVFGPGAMLDFIDQTLMTAHPNYWTN
                     TIKIQDDRLQATLRVNELRTPPTIDDRSSVPFVRFPRWYFCPKCRKFMPIEDWEKLYK
                     NAHKDKPMKIPICLTCSTKKSTKQLVPTGIITICEHGHIDDFPWVKWVHFRNKSGRKE
                     ICENPQILMKTGKSNLGLEGIELECSCGAKANMKGAFMRLKSSKSNDYGVPSEYKEMF
                     KCSGNSPWYNKKVNKCTKYSFASQRGASNVYYPKIESSIIIPPYSDTLNSKVLSSKGY
                     DTFKKFLDRAIKKNKLERFMDEDFEDFASDIAKETGFDTDKVSIVLKDLLPFEDSSPS
                     TTTRNQYREEEYEALIGNIDAKSKKTNDFTIEEQNLSDYDIPNFSKIVLVKRLREVRA
                     LTGFSRVNPPDNNIFGEEDIDDSCNDTKVISLRSRDCKKSFYPASEVRGEGIFIEINN
                     DMVKSWISSNPKIQDNASILNSRYNKDINVNDKAYRKITPKFLLLHTLAHLIIRELSF
                     VCGYATSSLRERIYCNNSENEKVMSGILVYTASGDSEGTLGGLVRQGMHDSLPSILNS
                     ALNRALWCSNDPICIDSTGQGRNSLNLGACHSCTLLPETSCEEYNLLLDRSMLIGDMD
                     NRDIGFFKNLILI"
     gene            complement(33889..37416)
                     /locus_tag="PC512_001822"
     CDS             complement(33889..37416)
                     /locus_tag="PC512_001822"
                     /inference="COORDINATES: protein motif:HMM:NF012493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HDF2441565.1"
                     /translation="MNCSELRDKTLDLVRKELLGPGSEDLCENIKYEIITDSPIERYS
                     TGILYPLNNNIDVSNTSEYDGEDNVFTSDDTQNELDRAISMSNETLPSSMGMTFFLKK
                     DAEVINFRVNYATYRNALYTDCHVKYTGDDFYSSNTINEYVELRGSFLYLKQKLTSEK
                     VYNLLKKHDLLDNAEAKFVLYKLANQCPDDENKTGGYVRVPHENLIVSIDMDKNYIKK
                     PISKDLDIVLSKRIYSNDFVSITCMLVNSQSGPKKYNNTIFQPELMVLAEDNNDLEFI
                     DIFTAGSVNTFKKLDSEEISLDLLYRNKKTFATGHGVAIDQDIQNDALIKLCTEFIPH
                     FEVPKLDFNVDELSDVSRELLSMKNLSDISDLSKDKKIYFLYKFVDAYDIWIDDLEED
                     SKDLSDVFKDVAYEHIKNCRDTKSRMLEGINLIKSNDEVYRAFSLMNRAILMQRCHSI
                     HITDRLPGSNNLDYIDYSNDNSAWRPFQLAYILTCLSSIENPDSKHRDLVDLLWIPTG
                     GGKTEAYLGLSAFTIFLRRIRNKENGNGTAIIMRYTLRLLAAQQFIRASILICACEII
                     RKENKSELGKKEISIGLWIGSDQTPNFNDEAEEMLNNLTGNNIKFRSSINSEYELDNL
                     KSKYNKFQLLKCPWCGTKLVKEWDKTSKKAVGDWGYRIKSRPKKFYLCCPEEDCSFED
                     MLPIQVVDEEIYNNPPTLLFGTVDKFAMITWTTEVASLFALDDDNSNLSPELIIQDEL
                     HLISGPLGTMVGLYETALDAMCSYKGIKPKIIASTATIRKAQNQVKNLYNRNVAQFPP
                     PGLTSSNSFFVKEMPLSKKRGRLYVGVIPSGKTQVTVEVRLMSALLQRLKMMENVELN
                     LLDKYWTLVSYFNSIRELGKCSTLLNDDIKDNMERLCKRVSAHPYQSLRNLNEQRELT
                     SRLTSTKINTTLDELSNTLTSNNLTVDTLLASNMISVGVDVDRLNLMVVVGQPKLTSE
                     YIQASSRVGRSNEGLIFTLYNPTKTRDRSHYEQFFSYHQSFYKFVEPTSITPFSEPAR
                     ERGMHAVLISMIRHILGLQANDLASRFSKNMDGVEDLKNFIIDRSIDIFRENNQNADD
                     NIVNEFKSEISSELDIIMDLWHDKAQISDKDNLLHYYKRPSKFDNKIYNNLLIPYDKD
                     VITNEKQTLNSMRNVDKQCTVEIIELEEN"
     gene            complement(37434..40052)
                     /locus_tag="PC512_001823"
     CDS             complement(37434..40052)
                     /locus_tag="PC512_001823"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441566.1"
                     /translation="MLTTNIHYILDNDICEIYFNKQRLTNSKYYQDNINVLNYIINEK
                     NNNLIINYNDKYIYAIYLLNIAINSYLNNTLNPNNHILTKLDKGMPLLYKGQIVIFKN
                     INNTHITLGHKNKTDTTLIPIDSAYMLITYNGHLEVNSMGKTPASKTFQTKNVLSSLG
                     FSDLKNMTGVINDSTLIILPCKDDISDLVSNIKIKDINNTYKFTELFPCSYISSTGAE
                     TDYPGNHAKQIPLLKFTTNISSAFEIIKSDKSIKNVFIIGDYPIYKHINDFERILNRK
                     RIESVNIVTSNSNISNILDLPNIDNLNIYSWSKDVLLTYSQDFENTSTFQKLWLDKLI
                     NKNICTTSVDSNISDLIHQARKSLYYISKYDFDISIKNSLMMCSYSLLKILENTPFNL
                     DFLEETIKLLNLNIATPSAKLENIKYLISSTSPDLELSALFDDVIVKFERIINELSDN
                     NTKFNTLNKLVSSYKYKTFTPNTPVILLQKQYEAIILKNLLKSRNINLQVISAEKFKD
                     SKTIKNLIMFGFYDLKYLDILNSDLIINITLYLYNSELSKYNYYMNQINSARNKIEKN
                     NKIYNLLDIKPFKPTYETNKLEAYSTDSPISDDDSMDEYISNYKFDINLNEIILSLSI
                     NQGIYNSKKEHVTSFMISDNNEYIFCTKKAIAYSIDWDKKSVRKKKLSEAKVNDWFLF
                     VDDYLNEEGELVINVIQKLLELNLLPSHYLDDYKLTNSWKSELKNYISYSKYNYNDVS
                     NSLAVLGEKINPITIKNWVTNKRLIGPIYLKTFEKIFKVIDSKLDHTEVYDATKSIRS
                     LHTKIKKSIDTFVSDNFFSSKSDIIKDEVSAVVLSMLGNTNDYVTPVQIREIHSCDKY
                     LSPHLVNKVLDLYSVY"
BASE COUNT        15905 a         4434 c         6293 g        13448 t
ORIGIN      
        1 tataatatgt aatatttttg ttttgaaatt tataaattag tattactggt tagagttagt
       61 ttagtattaa gtatattcga agtagttttt tagctatttt catacattta tattacttaa
      121 ttatatatag cctaactaac ttaatatatc agtgaaatat tgactaaaat gcctaaatat
      181 gttatcatac aagttagtca aataatttgg caacattaaa tatttagtaa atttctaaca
      241 tttatggaac aaatttctag caaagaaggt gagatttata tggctggtaa aaaaatatta
      301 gcaacaaaca aaagagcaag acatgaatat tttatagaag aaacttatga atgtggaatt
      361 gaattaaaag gaacagaagt aaaatcaata agacaaggca aagttaacct aagtgatgga
      421 tttgcatctg tagataatag cgaagtattt ttaaaacaag ttcatataag tccatatgag
      481 caaggaaata tattcaatgt tgattcttta agagttagaa aactattact tcataagcat
      541 gaaataagaa agcttattgg agcaactact ataaaggggt attcacttat accacttagt
      601 ttgtatctaa aaaacggtaa agttaaagta gagattgcct tagcaaaagg taaaaaacta
      661 tatgataaac gtcaagatat ggctaagaaa gatgcacaaa gacgtataga aagagaaatg
      721 acaggtaagt attaaactag ataaaactgt attttttaga ataaaattct ttattatcta
      781 gaacataaca ttgattttta ttcttaaaag tattatatta tatatacatt aaaaatttaa
      841 taaaaatggt gataaagttt gagaaaagtc tactggacta taaactactc aagggggcgt
      901 aaaggtttcg acgtgggttt ggaacttgag gctgcatgtc gtgttactct gggtcacgta
      961 aaaactgggg aactttaaaa taaacgcaga cgataatttc gcgatagcag cctagttgct
     1021 gctcgtccct cttagtcctc ctgccgacta agactggacg tcattatgca gggaactact
     1081 ttaggggtgt ctcgacttga agtagattaa ttgggactgg ctaagcatag agcctgccac
     1141 ttggcgctat gtgaggtgag atattagtga agttggctaa gcatgtagat gcagcaagga
     1201 aaagatttgc ggacaggggt tcgactcccc tcgtctccac cattgaaatc cacgaaaaca
     1261 tattgatagt ttagtcaata tgtttttttt gtgccttgaa atgatataat tataatataa
     1321 actaatgtaa aatttaacta aaaggagata gtataagtga gtatagataa taattttaac
     1381 catgttgcat ttctgtggaa tatagcagaa agtttaagag gtacatataa agaagaagac
     1441 tatagaaaag taatgttacc actaatagta ataagaagat ttgattgtct attagatgat
     1501 tatgatagag aaataataaa atcagtatac gaagaatacg acttcttacc agaagaagaa
     1561 agagatgagc tagtaatagt agacttaaaa gaaaatcacg acataaactt acaattttac
     1621 aatgtaagtg attttacatg gaaaaaacta ttagatgata gtgaaaatat aaaatcaaac
     1681 tttgaagaat atctaaacgg attctcaaac aatgtaaaag aaataatagg taaatttaaa
     1741 tttaaagatg aaataaatca attagataaa aaagacaagc tatatgcagt tcttagcaaa
     1801 atgtatgaag tagatctaca tataaactca gtatctaaca ataaaatggg atacatatac
     1861 gaagaaatgt taagaagatt tacagaaaac tcagcagcag gagagcaata cacaccaaga
     1921 gaagttataa gactttgtat ggaaatacta tttatgggta aagaaaactt ccttacagaa
     1981 gaaggaaaag taatatctat agcagacttt tgttgtggta ctggaggaat gctttcaata
     2041 gctgaagact atgtagaaaa aataaatcca agtgcaatag taaatgtata tggacaagaa
     2101 ctacttgatg aatcattcgc aatatgtcag gcagatatgc taatgaaagg gcaaaatcca
     2161 gataacataa gacttggaaa tactttaaca caagatagat ttaacggaga aaaaataaga
     2221 tttttaatat caaatccgcc ttttggtgta acttggaaag acgaagaaaa gaaagtaaaa
     2281 gaagaagcag acttaggttt tgatggaaga tttggagcag gtactccaag agtaagtgat
     2341 ggttcattac ttttcctaca aaatatgata agtaaaatgt atgatgatga agaaggaagt
     2401 agaatagcta taatatttaa cggaagtcca ttatttacag gagatgcagg aagtggagaa
     2461 tcaaacatta gaaaatggat aatagaaaat gatttactag aaggtataat agcactacct
     2521 actgatatgt tctacaatac aggaatagct acatatattt gggtacttac taacaaaaaa
     2581 gaagctaaaa gaaaaggtaa gatacaactt gtaaatgcta gtgaatatta tcaattaatg
     2641 agaaaaagct taggaaacaa aagaaaagaa ataagtcttg aacaaataga acaaataaaa
     2701 gaaatatatg aaaaatttga agaaagtgaa aatagtaaaa tatttgataa cgaagatttt
     2761 ggatatagaa aagtaacaat agaaagacct ttaaaactaa gctttaaagt aaacgaagaa
     2821 gctatagaaa atgtaaaaaa tactactcaa tttataaatc ttgcagtttc taagaaaaaa
     2881 gatatagaag ttaaagaaaa agaagaagct gaaggaaaaa taaaacaaga taagttaata
     2941 aaacttttag aaagctttga caatacttta gagtatatgg acagggataa atttataaaa
     3001 gatttaaaag ctaaatcaaa agagtttgat atacaacttt cagcaggact tataaaggct
     3061 atagttaata ctattggtgt aagaaatgaa gatgcagaag tttgtaaaga tagcaaaggt
     3121 aatatagaaa gtgatagttc attaaaagat actgaaagta taggtcttaa agatgatgta
     3181 tatgagtatt ttgaaaagga agtaaagcct catgttaatg atgcttatat agatgaaagt
     3241 agtataaata atataggata tgagatacca tttactagac atttttataa gtatgaagag
     3301 ttaagaagtt ttgctgagat tatgaaggaa gtagaaagtt tagaaagtga gatagcacta
     3361 aagataagga aggtgctagg gtaatgggat acagatatag aagtgatgat gagttaaagg
     3421 atagtggagt tgagtggtta gggaagattc ctaaggattg ggaagtcaga caattaaaaa
     3481 gggtactatc agatagaaaa gaaaataatg aacctataaa aacaagtaat atactgtcat
     3541 tgacaataga aaagggagtt attccatatt ctgaaaaagg tactggtggt aataaagcta
     3601 aagaagattt aacacaatac aaattagtat atccaaatga tattgtatta aatagtatga
     3661 atgtaattgt tggtgcagta ggactatcaa aatattttgg gtgtgcgagt cctgcatatt
     3721 atatgttata taaaataaat gctaacgatg atataagatt ttataattat atttttaaat
     3781 ctaaattatt ccaggatagt ttaaaaggat taggtaatgg aataatgatg aaacaatcag
     3841 aaacttcagg taagttaaat acgatcagaa tgagaattcc aatggaaaaa ctaagttcag
     3901 taaagatacc aattgctttt aacttagatc aagaaaaaat agcaaacttt cttgatgaaa
     3961 agacttcaca gtttgattca attatatcta agaaagaaaa gttaatagaa agattagaag
     4021 aagcaaagaa aagccttata agtgaggttg ttactggtaa ggttaaggtt gttaagactg
     4081 atgatgggta tgagcttata aagagaagta gtgaagagat gaaggatagt ggagttgagt
     4141 ggttaggtga gatacctaag gaatgggata taaaaagact tagattttta ggaaaactac
     4201 aaaacggtat aagtaaaagt agtgattcat tcggttatgg ttatccattt gttagttata
     4261 gtaatgtata tagaaatata gaattaccac atatagtaga aggtctagta aattcaactg
     4321 aagaagaacg taaaatttat tcagtagaag aaggagatgt attctttaca agaacttcag
     4381 aaacagtaga agaaattggt tttgcttcta cgtgtatgaa aactattgat aattctactt
     4441 ttgcaggatt tttaataagg tttagaccga atgataaaag actatacaaa ggattttcta
     4501 aatattactt tagatgtgat ttaaatagaa aatattttgt aaaagagatg aatttagtaa
     4561 ctagagcatc tttatctcaa aatcttttaa ataatctttc tgttgtattg cctaagtatg
     4621 aagaacaagt tgagatatat aatgcacttg aattaaaagt tagctacatt aatttatcga
     4681 ttaataagtt aaagtaccaa atagaaaaac taaaagaagc taaacaaagt ttaataagtg
     4741 aagcagtaac aggaaaaata gagatactag attaacttct agtatcttaa tatagatata
     4801 gattatacat acaaagttaa ataaaaggga gaattaatgg ataaaaatat atttcaaatt
     4861 aatataaata cagatgtact gataagatta aggaatcaaa taaatgaaga atattatata
     4921 tcttatagaa aagaatttta tgataaaaat aataaaaaac atcgcgcttg ggataaaata
     4981 tgtgcaataa tggataggct tgacgatact gtagattatt taaataaact caaattaaat
     5041 acaggtaaat atagacgaag tgcatttgac ttctttgaat ttatgaatca ggcttccgta
     5101 gtaatggatt gtataacaca tcttgcaaaa atatttgaag taccatatga agaagttgaa
     5161 acttcaactg aaatttttaa tgagcttgga aaagagggta aaggtacaga taaaaaatac
     5221 tttgaatatc tacgttcatt gtgttcagtc catccaatgg aaactagtag acacaaaata
     5281 taccaagaaa atagttttga atgtagtcct tatgtagttt ggaatgataa aagtatatgg
     5341 actaatgatg ctagcgattt atatgcagtg gtatacacaa gtaaagataa tgatagtttc
     5401 aaaagaattc atatatatat gaatcaaata tttgagtatg taaaaagaag agtaaatttt
     5461 attgaaaata taatagaaca tatagaaaag tatcaacaag aaataattga aatttttagg
     5521 aatactccaa taaagaaaga agaagatttt gaaagttata tagattattt aagaaatcta
     5581 aaaaaagaga tagaaataag atatggtaat gattcttttc atgaattaaa ctaccttata
     5641 gaattatttg atttgccatt atcaaatcct gataatgaag agaagatgaa cttatataaa
     5701 aatgctttaa aatatgctat caaatttgag cataatagta ttcaaaatat gacaaatgaa
     5761 ggttataaga ataatggaat attatatcca caagtgaata taacaactac attactagaa
     5821 gagctaattt cattaaatag tggtagtgag gagagacgta agtacagata tgcaatagaa
     5881 aaaacatcat atctaagcta tgatagttgt tggagtgata gagaatgggc atatgatcaa
     5941 atagatgata tgatgccttt tttagaaaga tacgtaacat ttgataaagc tcaaagtgat
     6001 tttgagcatt atgtattggt aaaactagca ctttatttag agtgcttaga aaatgaatgt
     6061 ttaataaata agaacgttcc taatgataaa aagtttcgta ttaaataatt atagctaata
     6121 aaatagggag agggaggata ttatgttacc aaaagaaaaa cacctagaag aatctattga
     6181 aaatcattta gtttcaattg gatatgaaca aggtcattca caagaatttg accttgaaaa
     6241 ttgcttattt gtagatgatt tatttagatt cttagaaaat actcaaaaag aattactaga
     6301 tgagtttaaa tacaacaggg gaagtaatta caaaaaagct tttatagatt tattaaattc
     6361 aaacatcaaa agaagaggtc ttataagtgt acttagaaat ggtgtagaag atataatgat
     6421 gaacggaaaa tttcaattat tctacaacaa accaaatcta actactaata aaacagcgta
     6481 tgaaaattat aaacaaaata tattcaaaat aacaagacaa ttaaaatata gctcaaagca
     6541 caacaatact ttagatatag tattatcttt aaatggattt cccgttatag taatggaact
     6601 taaaaatcag tttactaatc aaaatgtgta taatgctata aagcaattca aaaaagatag
     6661 aaacccaaaa gaaactttat ttggatttaa tcaaagagtg ttagtatatt ttgcagtaga
     6721 tactgatgaa gtttatatga caacagagct aaaaggagat aaaacattct tcttaccgtt
     6781 taataaaggt aacaatagag gtaagggaaa tcctgtagta gaaggaaaag aaaaaacttc
     6841 ttatctttgg gaagaaatac ttactaaaga tagtttactt gatattataa aaagatttta
     6901 ctttattcaa gaagatgata aaggtaatca aagagcaata tttccaagat ttcatcaatt
     6961 agatgcagta aggaagatag tagaagattt aaagataaat aaagtaggta aaaattatct
     7021 tatccaacat agtgctggta gtggtaagac taacactata gcatggactt cacataggtt
     7081 atcaagtctt catgatgaag aaaataatgc tatatttgac tctataattg tagttacaga
     7141 cagaaaggta cttgataaac aattacaaaa tgctatatat caattagagc acaaaaacgg
     7201 acttgttgtt aagatagatg aagataaaaa ttcatcagac ttagcagatg ctattgtaaa
     7261 tagagcaaag attattataa ctactattca aaaattccag tatgcactac ctaagataga
     7321 acaacttgat aaaaggcgtt atgcagtaat tatagatgaa gcacattctt caacatctgg
     7381 tgaaaatatg aatgcattaa aagaaacttt agcaggaaag actttagaag aagctaaggt
     7441 aattgatgcg gaaaatgaaa agaatgaaaa gtctagtata gataagatga atgagcttat
     7501 agagaaaaga acaaatttag gaaatataag tttctttgct tttacagcta ctcctaagaa
     7561 taagactatg caagtatttg ggaggatagg tgaagatgga ctacctcatg aatttcattt
     7621 atattctatg aaacaagcga tagaggaagg atttatatta gatgtactaa aaaactttat
     7681 gcctataagt gtttattaca aagtaggaaa gaaaattatt gataaccctg agtttgataa
     7741 gggagaggct aagagggcta taaataagtt tgttagttta aatgagcaca atataaggca
     7801 aaaggttgaa actatagtag atgattttgt agataatagg tctatgtggt tagaaggtaa
     7861 agctaaaggt atgatagtta ctgcaagtag attacatgct gttagatata aactagctat
     7921 agaccaatat ataaaagaaa aaggatatga tatgaaagca cttgttgctt tttctggtac
     7981 tgtaaaagat ggtgatgatg agtatacaga ggtaggtatg aataaggaag tagcaccaga
     8041 tattactgat tcaaatttac ctaatatatt tgataaaaat gaatttaagc tattaatagt
     8101 tgcagaaaag tatcaaactg gatttgacca accaaaactt tgtgctatgt atgtggataa
     8161 aaaactagat ggtgttaaaa ctgttcagac tttatcaagg cttaatagaa cttatcctaa
     8221 taaacaaaca tttatattag atttccaaaa tagtgtggaa gacatacaag atgcatataa
     8281 gccatatttt gaaatgacta atattgataa ggtaacagat ccaaatgtag taaatgacct
     8341 ttggtatcag ttacatgaat atgcagtata tactgatgag gaagtaaatg attttacagt
     8401 attattctat aaagagaaaa gaacttcttc tcaagatgct aagatgaata atttaattga
     8461 taaggcagtt gaaaggtatt gttatttaga agaagatgat gaaaaaaaat ctgatgagtt
     8521 taagaaaaaa tgtcaaaagt atattacttt ttataatttt ttaattcaga tttatcctat
     8581 aaagaactta aatcttttaa gattgcaagt ttatttagta gcacttttaa agaagttacc
     8641 taaaaagagt aaacaaagaa tagaccttga tgatatgtta agccttgatt attataaatt
     8701 gcaaaagctt ggattagatg ataaaaaagg aacggatata tccttatata atggagaagg
     8761 tgagttagtt ggtatatctg aaactgcgac ttctcgtgta agtgaagctg atgaagagta
     8821 tttagaggat ataattaaaa aaataaatga tgtttttggt gtaggactta cggaagatga
     8881 tagaattatg ataaatactt atgaagagat gtttaagaat gacaaggata tcatggatat
     8941 agctaaagct aatagttatg aagatttagt tagcactttt ggtaagaagt attttaagag
     9001 aggtatagtt aaaaccaaaa atagaaatga tagattagtt aaggagatat taactaataa
     9061 taatttacaa aattatatga ttcattattt agctgaaaag atatatgaag aggcaaatag
     9121 ataagatacc tatagagagc taattaactc tccataggta ctttattatg agctattgta
     9181 tattattcat cttctaaagg tgtagcaatt ccttttaatt ctaaaaactt taagtctaaa
     9241 tcaagaataa gctctatagt atctctatct atagaaacac cttctttttt acactcagta
     9301 agtataaaat caacttcttc ttcaaactct ataaatggtt tatcgttatt catatttttg
     9361 ctcctttgat taaatataat gtatttactt taaattatat caaagaagag aaaaaaataa
     9421 cattatttgt aaaaaactat atatatataa tatatagttt taccatatat agataaactg
     9481 tttttaatta aattataaat atatattata ttaatgaatc tatattaaat agatagttga
     9541 gtaagtagta ataccaaaaa tattaaaaag agatgttggt agaaatacga acatctcttt
     9601 tttagtgcaa aaaattaaaa ggaggaagtt aatatgatta aattatggaa gaaagaagat
     9661 ttaaatttat tattagaata tccaaaggaa gtagttgaaa atgttgataa cgtcattaat
     9721 attcttgatg aaaactatgg atgtaacaga aaattaacag atgatggtgg atatgtgtgt
     9781 ataattgagg atattaaaga agtagaaaac ttaaaatcaa atatattaaa ggggttagta
     9841 gaagagttta gtgatgtaat atatgaagat gaagttaata catataattc aacactatac
     9901 ttgttatcta gtgattatag tgttactgta atttctaaaa atgaagaaac tgagtactta
     9961 cttaaataag catatacatt gataaggtgt atatgcttat tttaatttta ataaataaag
    10021 gagaaaagca gaatgaataa aaagagaact cctgccaaga gagttgatat agttttactt
    10081 aaattagtaa aagaacgtag tgttctatat gaaactagaa aaataagtaa tctttatgat
    10141 gcttatagat tagcaaagaa ttttttataa atagtgctag agaaaagttt gtagtggtat
    10201 gtttagatac aaagaattgg ccagtagcat agaggttgta agtataggca ctgtaaattt
    10261 atctatggta tatccaagag aaatatttaa agtagctata ttaaccaatt catctgaaat
    10321 gatatgcttt cacaatcacc caatgggtaa tactgacttt agcaaggaag atagttataa
    10381 ctaatatgct acagaagcgt ggagaaatat tatgcattga attagtagat acatatagtt
    10441 attgtagatg aggataaata ctttagcttt aaagaaaact gtaggatata agagtcttag
    10501 cttaaataaa ttaggctaag gctttttcta tgttccaaaa caattaaaaa taaatcaaat
    10561 ttaggttaag cccggaaagc ccttgaaaaa aataatacat ataaatttaa aactaaatag
    10621 gagttgtaac atgtttaaaa aagaaaatag gtatatgaca aaagagatag ctgaaaatct
    10681 accaattgaa atagctatac tactatggaa tttaatagat gacttaacta cagaaaaaga
    10741 ttatctacaa ctatttgaaa taaatcctat aggattagga gtagttgaga tagttcataa
    10801 gcaagaagta cctgaatatg aagctaggat atatatacag aatgataaaa ttaaagataa
    10861 attaaaaata tatgttatag ataatgttga atatagaaca atgatgtttt caaatgaata
    10921 ttagttaatg attaaaggag agagagtaat atgataaata ataaatctga aataattaat
    10981 aagttatttt tcaatgaatt aaaagagtta atagataaat acaacaatat agatgataaa
    11041 actgtagatg taatagaaaa gatatttaca tgtatagaag atgaagaaat aaagaattac
    11101 ctaataagag ataattgtaa gctacaagag ctagtaaata catacaataa acttgaagat
    11161 ttaaacatag atgaagctat attctttgct tggtacaact taactataaa tacaatatct
    11221 atagataaag caagtgagta ctacgatgat ttaactacaa gtaactatat agaagtagaa
    11281 aatcatataa tatatacaaa tgaaagagat ttaaggaagt atgctgaaga tgaattagaa
    11341 actatgttaa gcatggaaca tcatatagat agattactac ataaagacat gttaatagat
    11401 atgtggttaa acaatacttc aaaagaagaa gtaatagaag aaatattaat gagtgatgat
    11461 atagaagata tattgaattt atctccagaa tatgcattta cattagctaa tggaatagaa
    11521 tatagatact cagaaaaaga agaataaaat aagtatatgt actgaaaaat acgggcttta
    11581 agggcttata cattaaagta catatttgaa aataccatag attttacaag agaaaatcag
    11641 aatgaaactt tttcaaatac tagttattat taattagtgc tagaaaagga ggtggagtga
    11701 tgactaacaa caataataat tgtgattata agggcatata tgcagatatg gttgaggttt
    11761 tgggtgaaga aatagtcatt aaattacata agtattatcg tggacaacaa ataacatttc
    11821 caatgaaact atattctatt gaatatgtgg aacgatatat agtgaagaat tatagaacaa
    11881 aaacaataaa agaaatgtgt agagagttag gatatacaga gggatggata aagcaattaa
    11941 ttaataaaaa tagattaaat tcaaagtaat tagagaagga gattgacagt agatatgata
    12001 ttaacagtat tagcaatact tatggggaca ggtatatttt ttctgattaa ttcaatgcta
    12061 gatataacgt attttggatg tggcccaata ggatttttat ggtttggatg ttttattgtg
    12121 tcatatgcaa tattaacatc attaggtggt atagttttag gattgttaaa gtggatagta
    12181 ataggattga ttatactatt tgtaatagga ttaatagcga ataagataaa tgattaaatt
    12241 actgtagatt attttgataa aataattatt taatatattg aggcattaca tgatagaaga
    12301 ataaatataa atgacttaaa atctttaact taactaaaca aaaaatatat tatttattac
    12361 aaaaaatgac aaaaaaatta aatattatat tgtattatga caatataaaa cattggagtt
    12421 tataaattag gaggaatatt ttatgcaaga ttttgatttt ataagtgaga caataaagaa
    12481 atttcaatcc gatttagaaa acatggataa ggtaaatata cttgttgtag gtaaaacagg
    12541 agtaggtaaa agtacattaa taaataatat atttagagaa gaattagcag aaactggaat
    12601 tggtagacct gtaacacaac acttgaaaaa aataagcaaa gaaggattac caataaattt
    12661 atacgataca aagggattag agttagaaga agatgtgcaa gagactataa aaaaagagat
    12721 attagatgaa atagaaaatt gtaatagaaa ttcattagaa agaaatgata aaagtgagtt
    12781 aatgcatgta tgttggtatt gtataaatac atcagtagct agatgtgaag aaactgatat
    12841 aaaatggata aatgagttaa gtgaaaagat accagtaata gttgtattga cacaaggatt
    12901 cccaagaaaa aaagcaagag aattaaaatc tagtattgat gatttaaatt taaactgtaa
    12961 gaatgtaatt ccagttttgg cagagcaact agtagaagaa gaggatgaga tagttataaa
    13021 gtcatatggt ttagataaat tagtagaagt tacatatcaa gtaataccaa aagaggtcaa
    13081 gaaagctttt gttaatgtac aaaaggtaga tataaaaaaa aaggttgaag agtcgagaaa
    13141 atgggtttta ggatatgtag gaggatcagg agcaatagga ttttcaccaa taccattttc
    13201 agatgctcca ttattagcaa ccgcacaagt tgctatgata tctcatataa cagtaatatt
    13261 tgggttacaa gttgataaag ctttactaac ggcaattgta agttctatag gaggggttac
    13321 atcagctact ttactaggaa aaacattggt atcgaatata cttaagttta taccaggagc
    13381 tggaactata gcaggtggag cgataagtgg ttctgtagcg gcattaacaa ctacagcatt
    13441 aggaatggca tatataagtg tattagaata tatactaaat gagaatatga aaggtaatga
    13501 ggttaataat actgaaatag ctgaaaaaat gaaagatgca tacaaagatc aattaggaat
    13561 gttatctaag aaataattaa ttcaagataa agtataagat taattatagg gaaaaagtaa
    13621 aatttaaagg tatatttggt aaaacataaa caaaaatgat aatggcgtca atattatttg
    13681 ttgtcatatg tagtagctta gtatatatat tattgagtga taggtttaat cataagttaa
    13741 tttacttaga gaaagatata ttagatttaa gaaataaaaa tttgtaacta gctaataaag
    13801 gatcagtata gaaacagata aacaagagga taatgtagat attaaatcta aaaacactaa
    13861 taatgaagaa tataaaactt caaaactatt taggcactag atagagtatt tgctataatg
    13921 aataagctaa tagagaaatt aaaacgttta tagtaagata actaattcaa atacatttag
    13981 tggacttcaa ggaacatttg atacactatc aaactatggt agccaattga tagaccaatc
    14041 atctaaattg aatttatcaa atgttggatg gttagaaata tctgatataa ttacaagtat
    14101 aggaaaggac tattagattc tgaaaatatg tcatttgaag cattaaatat aatgggaaaa
    14161 ataggaaaat ttataaatta tattgaaatt aattatatta actaattaaa tattgataca
    14221 taatgccttg ctacagttaa atgtggcaag gcattatttt tgtaaagaaa ggaagaatta
    14281 acatggcgaa gcaaagtaaa gaggaactat ttgaaaaaga aactaaatat tgcaagataa
    14341 taagaagtgt aacagtagaa gatggagatg aaagatttgc aatagagaaa atatatatta
    14401 agtcattaca aagatacgag gttagaatat gcctgtatcg tgactgccga gatagaatta
    14461 ataaacttat tccaaggcct gtagatttaa ctatggataa gtttgtagca ttaatactgg
    14521 taggattaaa ggctggtgta ctagatgatg atttcaagca agaactaatt aaaggtttag
    14581 cttaggaggt agaatatgac aatagaagag tttactagtg gagtaatgtt tgggatttca
    14641 atttttagtg cagtattaaa gcaagtatta gaaaataaaa aatagtatac aggaggtatg
    14701 agtatgattg gatttataat aggaagtata ataggaattg gactatgtat tagtatagag
    14761 atactgatat cgaaaaatgc cataatatac taagttatat ttaaattatt aatagattca
    14821 tatataattt atttaagccc ttaaagccca gataagttat attaaagtaa agtttgtatt
    14881 tatgtaaatt aaataatata tattattata aatttgaaag gactttataa atatgaaagg
    14941 caatataaac aaaaaagata tagatttaag taaaataaca tttgataagt ttttagaaga
    15001 tgaaggatta caaaatagag agagagatta cttatatgta gatgattatg acaatacttt
    15061 agatactcaa gaatttaaat tacatataat tgaagagaat actgataaca catatataga
    15121 taaagataaa tactggtatt tagatttaga tgatagttta tttgaatacg aagaagatga
    15181 agatactatt gctaaaacat tatatagtct aatagatatt agaattaaat ttttgaaaca
    15241 tgttgagtat agaaaatata taaatctagg agtaatagac gaagaatatt ttgatgagat
    15301 taaatcattt ttgaaatttt atatagtagc aaaaacaaag aaaaatgagc taggtaattc
    15361 aaatttaaag cagatggcta tagatatttt tgataaagaa aggtttgaag acgacatatc
    15421 agatgatgat atggaaaata taagtgaatg gataggagaa gatcaaaact ttaaaatgtt
    15481 ttatgataaa gtttgtaggg atctctcaaa ttctacacag gataaagaaa tattaaaatt
    15541 agcaggaatc aggaataata aagtaaaaca ttacaaagga agaaaaatta gtagaaaatg
    15601 taaattagaa cttaaatcat tgactaaaat gtgggagtat gaaactaaac tgactcatga
    15661 tgcaaataag gcacataaga aaataaaatc taatatgctt gaaaaaatga cagataagaa
    15721 ttataaaaat atatatgaat atttaaataa tgagattata aatagtaatg aagaatataa
    15781 aaatatttat ttttatagct tagaattaaa gttagcgaat gaattaagaa agtgtactct
    15841 taaaaactta aataaaatta aagacataga aaatcaagta aaatttattt cttatactat
    15901 tgcttatata cacatagttc cagttttaac gataagagag aaactaagcg ataagttatt
    15961 taatatattg tcaactaatg aaggtaagga tatagaaaaa tttactaaag aagttagtct
    16021 tataatgaga attataaata tagaatgttt ggagttatta aatatagtta gtaagaacaa
    16081 ctattataaa aattttagtg aaaaggaatt agaggagttt aaatctattt ataatataaa
    16141 taatggaaga aagtcatttg aaaataaata taaaataaaa gtagattata atatagatga
    16201 tgtaagaaag tatggagagg ttataaaagc aataaatata gaaagtaaga agaaaattgt
    16261 agatagaatt aagaagaaga gaaaatctaa ttagattttc tctatttttt ttgaaaaaaa
    16321 taaaaaatat ttggtgaaaa cgtttatctt taggtgatat gagtagtcat tatttattat
    16381 ataatcatat ttgtaggaac gagctaatta ataaaatcta agaacaatag cttaatgatg
    16441 aaaaagtacg gcctttcggg ctttgacaac aggaggtata ttaatgacaa actttaaaag
    16501 tgtaaaggta gaattaattc tacttattga atgtgaagaa ggaaatcgta atgaattaga
    16561 aggtatgatt gatgaaggtg tattaaatga aaaagaatat agtttaacta tattaggtag
    16621 tacagagtat gaagataacg caagggctat ttacatactt atgaatacag gaggatcata
    16681 cgaaaaaaac ttacaacgat taagtagatt acacttgaaa attgaaaact tacttaaaga
    16741 tacaaatgtt aaatatagag gtatatcttt agtaccgaat attgttaaat gggataaata
    16801 ggaggaatac aaatgagcaa ggcaataaac agagaagaat taattaaatt atatgaggaa
    16861 ataggattaa atgttttaga taataacacc gttatgaatt catctaataa aaagatatgt
    16921 aattttttag taaatataat agaacaaagg gttatagatg gaaaaatgta tttatgtata
    16981 aatgctatgg ggattaatgg agagctatta tcagaggtaa tattagattc gaataccata
    17041 aatagaacta catgggtgat tgaaaattgg ggttttaaat attctataga taaaaaatat
    17101 attaatgact ttattgaatt gatacaacac ttatgtatga atataaaaac taagtatata
    17161 tatgaccata caggatggat atatcaagac aataagtgga tatatctaca tggaggagga
    17221 gttataggag gttcagatgt tcaagttgag ttagatgaat caatagataa ctatatacta
    17281 ccagataaaa ttagtgacat aaataaagca tgtgaaatga gtttaaagct agtagactta
    17341 atagaagatg ataaaggtat tatattctct tcattagttt acctatctcc acttattgaa
    17401 attatcagta gaaaaattaa accaccggaa aatatagtat ggacatatgg aaaaacagga
    17461 tcaagaaaaa cagcagtatc aaaagttgta ttaagtcatt ttggtgattt taataaaaaa
    17521 attccagcta catttaatga tacgattaca gctattgaat taaaagctaa taagttaaag
    17581 gatagcttat acttatgtga tgactttgca cctaaacaag actttaggga taaaaaaatt
    17641 caagactcaa aggcagaatc cattataaga atgtatggag atagagtagg gaaaggacgc
    17701 tcaagtaata agttagatat aaaggatgct aagagaccta gaggaatgat attaataaca
    17761 ggtgaagatg tgatatgtgg agaatcatct aatgctagat tattatcaat agaattaaat
    17821 agaagttcag tagatttaaa tatactaact gaattacaga ataatagtca tttgcttgga
    17881 gaagcaatga gaggatatat agaatggtta ttatctgaaa tgggaaatat tgatgaatta
    17941 tctaatatat tattatataa ctttaaatct tacagggatg aaattagaga acaatataaa
    18001 gatgatatac atggaagaac tattgagtct agtgcatgga tattagtagg ttttagttgt
    18061 atgttaaatt atattagaga taaaggtgtt atagataagt atgaagatga tgagtacatg
    18121 gatagagcga ttaaagttgt agaaagatta atagaagagc agataaaatt aatatcgaga
    18181 aactcaccta tagatatatt tttaaataca ttaaaggaat caataaattc aaagtcaata
    18241 agaatagcaa cattaaatga ccagaaccaa gttatagaag ataaattaga atatatatgt
    18301 ggatataagg ataaggaata ttattacttt tacacagata aagtatattc ttttatagaa
    18361 tttgaaaata aaaaaagagg tatacatttg ggaataagtc aaagacaact agtgaaacag
    18421 ttaagagata gtggaattgt gaaagttgat tctaacaatg attctcctaa aaaaactatt
    18481 catacaaaag atgctagcga ttcaacagga tatacaacaa taagaccaag aatgcttcag
    18541 atagaaagaa gtataattga gaactttcaa atataactta taatcaagag tgcttatgta
    18601 ctcttgatta tattctatga taaatggagg atataaatat gacagaaact tataaaatca
    18661 gcataggaag aaaagattta tattctaaag actataaggt agttgaaaga actgactatg
    18721 aaaagagaca cacagttaat ataagtagaa gcttagtaga catactttct atacttgtaa
    18781 aagaagatag atagattaaa atatggttac acacttagtg ttagtgtgta gcctttaata
    18841 tagattaaaa ttagtatatt taaactttgg aggaaataat atgacaggaa agaaagcagt
    18901 agtatatgca cgctttagtt cagataatca aagggacgaa tcaatagatg ctcaattaag
    18961 agcaataaat gaatatgcag ataagaataa tataaaaata gttaatcaat ttatagacag
    19021 agcaaaatca gcaacatcag ataaaaggcc agagtttcaa aatatgatta aattctgtga
    19081 agcagataca acaggaatat ctatggtaat agttcataag ctagatagat tttctagaga
    19141 taagtatgat tcagctatgt acaaacagaa attaaaagta aaaggaataa gagttgtaag
    19201 tgtattagag aacttagata attcgcctga atccctaata ttagaatcag ttatagaggg
    19261 aatggcacaa tattacagtg ctaatttagc gagggaagtt gctaaaggtc agaaagaaaa
    19321 tgcccttaaa gcccttcata atggaggcga tgcaccatta ggttatgatg tagcacatga
    19381 taaaacatat acagttaatg aagaagaagc tcaagcagta aagattatat ttgatagata
    19441 tattaaagga tattcatata gtaagataat agatgaacta aatatcttag gatataagac
    19501 taaaagaggt aataaatttg gtaagaatag cttacatgga atattaaata atgagaaata
    19561 tacaggagta tatgtattta ataagactca gagaaaaggt gtagatggaa aaagaaatgg
    19621 acataagcaa aagagtgaag aggaaataat aaaaatagaa ggtggtatgc cacaaataat
    19681 agacaaagga gtatttaaac aagcacaaga tatgattcaa aaaagaaaga aaactccagg
    19741 tgcacataaa gctactacta catatctatt aacaggacta attaaatgtg gtgaatgtgg
    19801 acatgcattt caggggaata agagaaaaga ttcttatgga aatgaatatg tttcatatag
    19861 atgtggatgt agaaagcaaa agagagaatg taataataga gagataaaaa gagactattt
    19921 agaagagttt atattacaag aacttgaaaa gaacatatta aatgatgaag ctataccgat
    19981 tttaagtaaa gcattgaatg agaagctgaa tgataagaat gaaagtaatg cagagctact
    20041 taaaaatcta gagcagaaac tagataaggt aaataaagag ataagtaata tactaaatgc
    20101 tataatgaat ggtatagtaa atagcatgtt aaaagataag cttgatgagc tagaacaagt
    20161 aaagttcaac ttagatttaa aaatgaatga actaaagata gaaaataaag ttgtagatgg
    20221 tgtaggtgta acagaagatc aaataagagg tatgttttca agatttaagg aatttgtact
    20281 agagagaaat atacctgaat gtaagaagtt tataggagac tatataaagg aagtaatcgt
    20341 atataaagac cacattgaag tcatattcaa tgtggtcttt tgttttgttg acaatgatat
    20401 aactcatgat ttacatatta tcacagaaag gggtaaaatt acatagtaaa tatatatttt
    20461 ataaaagtaa atatcagata ttatttagat aaaaattatt tttgaaaata ttagttttaa
    20521 aaaatatatt tatataatta taaaataaaa tggtataata aaactttaaa tatgataaag
    20581 aggtgagact attggcagat atatttacag tactaaatta tcaaggtagt aaaaagagat
    20641 tattagattt tatatatgaa aatacacaag aatatattga ttctgataaa gcttttttag
    20701 atatatgctc aggaacgagt gcagtagctt ataatatgaa aagacacttt acggtttata
    20761 caaatgatag tgaaaattat gcatatcaga tatctaattc aattgttaag aataatgaaa
    20821 gatataactt tagtcaatca gatgaaatga tcataagaga aaaatataat attaatttac
    20881 aaagattaaa taatattttt aacgatatgg taaatcagga agatatgtta ttagaacaag
    20941 aagatgcaga cggtttaata gagctatatt caaattgccc atgtatatgg aaaaataatg
    21001 ttgatattga aatagaaggc aatacaatac agagtatata tgatttaaga aaatgtaaac
    21061 gagacatacc gaatgtgtta ttcacattgt attattcaag tagttacttc ggcataaagc
    21121 agtctatgga gatagattct attagatatg ctattgaatt tatagaaagt gaaataacaa
    21181 agagcattct ttttacaagt ttatttttcg caatgaaaga gtgtgttttt gctaaagatg
    21241 gtcacatggc acagccatta aatatggaaa caggcaagaa aagaatgtta agattaaaag
    21301 caagaagtat atatgacata tttatagata aattaaagga atttaatact gaggagtttg
    21361 tattatcaca aaaggagaat aagtgcttca ataaagactt tagaacatta ttagaaacag
    21421 aagaaagtat aaaagatgaa gttggtttta tatatataga ccctccgtat acagatatgc
    21481 aatactcaag atattatcat attcttaata cagttgtttt gtatgattac ccagaaatat
    21541 cattgagtag aggaactata tcaaaaggga tatatagaga aggtagatat caatcacctc
    21601 ttagtcaaag aaaacatgca ttaaatgaga ttgatttctt atttagtttc tgtaaggaaa
    21661 ataaaataaa tgtagcatta agttatgcat atccaataga tacagaaaaa caagcaacta
    21721 atagatatac ggctagtatt gatgatttga taaatgtagc caaaaaacat tttggagata
    21781 atgttaaggt agtacatgaa gaatatagtc atgcaaataa tagaaatagt gataaaaaga
    21841 atgtacttga atatttaata atgggtatac acaataagga gtaaatatgg ataaaattaa
    21901 taaattaaaa gagaggatag ctaatataga agcgacgaat aaaaatgata tatattcttc
    21961 taacttatat tggtcacaaa aaccattcaa tatatgtgat gaaattattg aacatttaag
    22021 tgaagatgga gatataatat ttgatccgtt tatgggatct ggggttacag ttatagaggc
    22081 tttgaaaaaa gagtataaaa gaaatgctat tgggtgtgat ataaatgatg caccaatatt
    22141 tatagtaaaa acattattag aaaaatataa tgtgcctaaa atagagaaag atattaaaga
    22201 gctaaataat aaattaagta aattatcaac ttactattca acaaaatgtc gtgaatgtgg
    22261 agaagtagtt actatatcga aaactatatt cgataaggag aataggaatg caaagtgtga
    22321 gctaaagtct atacattata aatgtaagga atgtaaaaat gactttaaag gtgaaccaaa
    22381 tgaaactgaa atatctaaat tctttattga tgaagaatta aagaatatag atgattttca
    22441 attcatagcc aattcaaggc ttgcagttgg cgaaggtgat acagtaagaa ctattttttc
    22501 aaatagaaat ttaatagtat tagataaaat attaggacat atagatgaat ataaaaatag
    22561 tgaatcttat gagcctatga agtatatttt attatctatt ttacatttaa gtaagattac
    22621 agatacacat tctaattctc agtggccttt atggattcct aaaaaagact gtgttgaaaa
    22681 aaatgtagta gaattattca taaagaatag taagaaaacc attaaggcat taaaactagc
    22741 atctaaatat ttatgtgaaa atagagaaaa tgtagaacta atcaaaaatc tagatagagg
    22801 gaaatttaaa ttgataaaag atggagttca aaatatagaa gatgatgtta tacctaatga
    22861 atttgtggac ttgataataa cagatccacc atatatggga caagttttat attcagagta
    22921 tatgcagtta tataaacctt ttatggattt ggaattcgaa ttagaaaatg aaatagttat
    22981 atcaagtgcc ccagctagag ataaagggaa agtattatat tttgatatga tgaattctgc
    23041 atttgaaaat atatctagag tattaaaggt aggtaaatat atgtgtatgt acttccatga
    23101 tagtaatcta gatgtatggg ataatataat agatataatg accaataata atttgaaata
    23161 catgggacaa attcatgtaa gtaagaataa aaacactctt aaaaacatac ttagtcctaa
    23221 gaagtcgtta aatggagatt gtataatttt ctttaagaaa gatttaaata taaactatga
    23281 tataaatgaa gtagataata tagaagataa gataaataat attgcacaag ctattataga
    23341 tataaaagga tacgcatcaa ctccagagtt atatgataat ggagcactag agtatataat
    23401 atcaaacgga aaactaaaag agatttctaa aaagtataag gatttaacaa gtatatttga
    23461 gcaaagattt aattgggata aggaaagagg ggtatggact gtataataaa taaaaagcat
    23521 ctatagataa ttatagatgc tttttattta tattttatag taaactaaat atttaataat
    23581 ttctaatttt tatacaatat gttaaaggat tggctatcca aagatattat ttaatataat
    23641 tttttagcat taactctagt taaatcactt ttagataatg aaacctgtaa tcttctgata
    23701 ggagaaccct tttctaaaca tctattgatc ttttcctgta acttcttacg aagaagagga
    23761 actacatctg ctggttcagt tgagtagata tgttcaactt ctatattttc tttatcaaca
    23821 actgctaata ttatagcttt atcattataa tatttattta gtacattatc agatatatct
    23881 tgaaagttcc aagcatgatt tttagaaact ttatattcat aaggattacc ttcactatca
    23941 taggcatcat gagcaccttc tcgtccacct tgctctgggt ttacttgatg gtttaattct
    24001 aatgcaacta ttaattccca aaacttatta cttgtaagta aatttttaac tcctgttaat
    24061 tcttcaagtt cacttgaagc tttataaata gcacttagat atttatcata aacaccattt
    24121 tgagctgatg ggattatctt acttgcattt aatctagact ctagttgatt agggctgaca
    24181 tttatcattt ttctggaatt ttgtatactt tgagtatact ttagtaaata ttcacacatt
    24241 atatctccag gtatagagta ataccaatca agctttccag ggtaaggaaa atcaacatca
    24301 tttatatgag caaatataac tgccttagct ttctttaatt ttgctatact tgtatccgaa
    24361 aaatcattaa acgtccaaga atggttagag ctacttttct tgaaatgttt atattcaaac
    24421 tcatttccga attcatcttt tgcatctcta gaaccactat gtccaggtat tagtatgtga
    24481 ttaagtgaat tagcagtcat aacttcatat attttgctat tagaaagtat atcatttact
    24541 ttatattctt taaaaatacc atcttgtata gcctttagtt catttatttt ctgtgttatt
    24601 aaaacatttg ttatattatc tcttatcata ttatcatagc tccttaataa attagtattt
    24661 ttagataagt catttttaat tagatttatc acataactat tgatgctatc atttttaaat
    24721 gctactaaat ccaataaatc tttatgaaaa tcatccttga gtcttatagt tagttttttc
    24781 aagctatcac ctcggatatt aattagatgt gccgtcgaga taagtataat taagcaggtt
    24841 tataaagtca aggattaaaa aaattaaatt atagatatat aaaagtatat atagcaatat
    24901 agataaatag ctaaactatt aatcgtgggt attattcttg cgattcgtct ccaccaattt
    24961 tgaaaaaaga atgatgaaat acttggaaat actagtcttt gttgactagt attttttatt
    25021 ttggagaaga aatccaccaa ccgtacccca accacagaaa atgaggtttt tttgggggta
    25081 tattggggtg catttaggct gtataaaaag tttttatttg tttattattt tatttgttta
    25141 ttattttatt tgtttattat gataataggt aacatagaat tttaatatct actttatgat
    25201 ataatatttt tataaatgta agacagttta agttgttaat tagtaaaaat atatattata
    25261 taagcttgat aggagttgag gtttgtaatg gatgaaagaa aactagaatt ttctattttt
    25321 tgcattgaag ctttagcaga aaaattgaat atagattcag aaggagttta taaacttctt
    25381 aaacatgata ctgatatttt agataactat ataatacctt gctatgaagc actacattct
    25441 caaagtaaag gttacatagt ggaagattta atgcaagtac ttaaagaaaa gggtgtgata
    25501 taatgattgt atatcatggt tcatattgtg tggtaaagac gcctagtatt accttttcaa
    25561 gagattcttt agattttgga aaaggattct atgtaaccag tataaagaca caagcaatta
    25621 actggacaga gcgttttaaa aaaagaggta aaaaagcata tttaaatagt tattctttag
    25681 atattgataa attaaaagaa aactgcaagg taaaaatctt cgatagttat aatttagaat
    25741 ggcttgattt tataatagaa tgtagaaata tgagtgatat atatatgaaa tatgacatta
    25801 taataggtgg tattgctgat gataagattt acaatacaat agaactgtat caagataatc
    25861 ttattgaaaa agatgaagct ttaaaaagat taaaatacta taaaccaaat gaacaaatat
    25921 gtataaccaa tcaaaatgta atagataaat atttaaagtt taggtatgaa gaggaggtat
    25981 aatgattatg gaagcaaata aaacattatt acaaatacta tataaaaaaa tcatattaga
    26041 attttccaaa caaacaggta agagcttgga agaaagtatg gattatttat atacttctga
    26101 aacatataaa cttataagtg agggtgtatc agatatgcac tgtaagggtc atatatactt
    26161 ggctcaagaa ttaatgttag aaaatggatt aatgtaccat aagggctatc caagataaat
    26221 aattaaaact agatacgaaa taaggataca atataatata aaattaattt gtatccttat
    26281 tttgattttg taattaacta tatgaaatca caatatttat atgtatttga tttttacaat
    26341 gaaaatattt tatccaactt ttctacagct tcaactttct tatcttccat aacttgagta
    26401 tatatattca aagttattga tatatcataa tgacccatta aaacttgtac agttttagga
    26461 ggaacatcat tctcaaaaag tctagtagca taagttttcc taagaccatg aaactttata
    26521 ggctctatat ttaagctatt taatatagac tttaaattcc ttaaaggtct tttatcatct
    26581 atagggatgc ctaattcatt gcaaaataca taattattat ttatatataa ttctccagcc
    26641 tttaatatat ctgtattttg atttacttta tgctctttca atttatttaa aacatctttt
    26701 ggaataggta cagttctgta agaatttgat gtctttggcc cttgctctaa tactttaagc
    26761 tctctatttc cagttttatc tataaaatat gttctttgaa gagttctttt aactgttaaa
    26821 ttagactttt taaaatcaat atcaaaccat ttaagtccta ataattctcc taatctaagt
    26881 ccagtaccaa gagcaagtaa aaataatacc tctaatttat gcccatctat agcttttata
    26941 aaactctttt gttgttcaag agtcaatatt tcaagtttgt tttctttttt ctcaactggt
    27001 atatttacca tagtacaata gttacgttgt ataagacctt gtttttcagc ttctgataag
    27061 caggttttca gtttagtgtt tatttgcctt atagtaggta tacttttatt ggaatcaagc
    27121 aatctattgt aatatttttg tatgtgagat actcttaagt actttaattt aacattgcct
    27181 aaatcagtat ctttaatata attacgatag atgctttcat atctttcaaa tgacttgggt
    27241 tttaaatctt ttattctata ttcaaataac caattgtaaa accaatgctc taaagttatt
    27301 ttatcatctg aaatatcaga gcttaaataa tattgttttt tataagcatc taatttatct
    27361 ttaacttcct tttgagtctt accataaaat tcttttctca gtggtttacc atcttcatta
    27421 tagccaatca ttatacggga acgccaacca tctttatatt ttccgataga gccttctcca
    27481 ttagctcttt tagttgccat ttttaaacag ctccttatat gatttatagt tatatccatc
    27541 aaagaatgta atacatttct ctaataagaa ttttataact tcatcagctt ctagtgtttc
    27601 atagaagttt agcattaatg tgttgtactc ttgtttatgt ttagctggta ttgatagaac
    27661 tcctatatca ttatttataa gtattaggtt tgaggtaagt ctagcagttc ttttgttgcc
    27721 atcatagaag aattggcaat aggacaacca taaatttatt attatagcct tttctaatgg
    27781 gttagttatt ttatttatga tatttatgtc atttacaaat aaatcattta atagagtggc
    27841 ttctatgcat tcatattgag tagtaccagc tatacctata ttaccatttc tgaaatctcc
    27901 aacgattaga gcttcatctt ttgcaactat tttatgtata gagcaaattg tatctttatt
    27961 taaagataag ttttctttgt tacttaattt tattacataa tcccatgatg attttatatt
    28021 tagtatttga ttttggtcac ttaatttatg tccgcctacg gttataccat caagtaatgt
    28081 ttgtacttct gggaatgtga aggggttatt ttctaggtta cccatatcat atacaaattc
    28141 acttatcatt cttctaatgt atgttaaagt atatttttta tctccatgag gtatattagt
    28201 agggaattta tgtgtgtatt ttggtatata tgatttattc atgattttag ctcctttcat
    28261 atctaatttt tatttattaa ctatgaatgt ataaaagtta ataggtaaac tcatattttg
    28321 aaaatgtgca atactaatat tcttcatcct catcttcaat aagaccatta gagttttctt
    28381 gtataaaatt ttcaacaaga ccatttatca cccaatttag atttttggag aagtctttga
    28441 agtcagagaa gtttaggtta attggtttta ttgtatctgc attatctgta atttcaaact
    28501 tttttttata gtctgttttt atatcataac cataattttc taatatgtga attactaaat
    28561 ccaactcttt atcaaatact tttaaattaa tattattatt tgttaaagta tctaaatcat
    28621 tttcttcaac aatgagttta tttatagcaa ttgataaagc agtagctatt tttcttatca
    28681 tatctaaact aggcattctt tgattttgct catatttagc tatagcatga actgaacaac
    28741 caatcttgtt ggctagctca tcccttgaca tatttatcga ttttctatat tgtttaatct
    28801 tttctccaat tgtattattc atcataattt caccttaaat atatcatcaa acaatgattg
    28861 tacttctaaa catgtaaagg agttattttc tagattatcc catatcatat actaaattac
    28921 tcataactct cttagtgtat gttagagtat attttttatc tccatgaaat aaattagtag
    28981 gggatttata tgtgtatttt agcatatatg atttattcat aattgtaact ccattcatag
    29041 ttttttatca ttgctttaga tagtattgat attattttat attttagtta gtagtttttt
    29101 tatttcttta agtgtatttt caagcttttc atttttttcc tttagttcgt tattttcttg
    29161 taataattta aagtaatcat tatttttaat agtaatattt tctttttgag atattaattt
    29221 ttttagtcga atattacttc cattatctgt tgagtcacta aagtaatcat agattgtttc
    29281 tatactttct tctgatagac caatatctaa taattcatca attgattgtt ttgtaagaac
    29341 atcattttta ataatttctt ttatgtcatc aggatgtaat gaaaaatcta attcagtatt
    29401 agatatacaa tctgaaagta tccaattata aacttgattt tcatttagtt ctaatttttc
    29461 accaagttta taatattggt ctttatcaga ccaggcacct agcaataaac ttgaggtaat
    29521 tctaatatca tcttccataa gatttgaaat agcatttaaa aattcatcaa aagaatagta
    29581 ttcttctggg aataaagact gtaaaaggta taaaacatct tcattagtca ttacttcatt
    29641 ttcaatatca aaataaaaga tagtcttttc aattttcaaa gctttagcga gttttgataa
    29701 ggtatctata ctaggtattc ttttatcatt ttcataattt attagagcat ttcttgagat
    29761 gccactaatt tcagcaagtt gaatctgcgt tagctctttt tgttttctta tcttttttaa
    29821 gttttttcca atttgcaata ttatcacctc gtataaagta tatcccaaaa gtacacaaat
    29881 gagaacagaa aaataatata ttcttattaa cagtacacat atatcgacat tataattaaa
    29941 atgtaaagtt tacgaatgta aactagaaaa aaggaggaaa aagtatggga atcaatttaa
    30001 aaatatttag gattaaaaaa ggtctaaagc aacaagaact ggcagataga gttggtatat
    30061 caagatatta tttatcaaac ttggaaacag gtaaggctaa taatccaagc aatgatttga
    30121 tgattaaact atctagagct ttagatacaa cagtagaaga attatttttt agtaaggagg
    30181 attaaaatat gaaagagaat aataatttag aggttttaaa gacattacaa gccactttaa
    30241 acattattgt aaagaatgaa gaagaagcac aagaaaaaaa gcaaggatat aaaattattg
    30301 aaaatgcgaa aagaaataaa gctgagctta taacatgtaa agaagcatct aagctttatc
    30361 ctataggaga atcaaaattt aggcagttat gtcattctaa aaacaaagga ttcccttgta
    30421 tatggataaa taatcgagta tacataataa aaaataaatt agatgattgg tttattgaaa
    30481 atgcaaatgg tatcaagtta tagtcttaaa gtaggtgttt gcaattgagc aataaagggt
    30541 ggataaagct ttatagggag ttgttggata aatcaatttg gaaagatatt aaaccagaaa
    30601 gaaaggtaat attaataact ctattactta tggctagtca taaagaaaat catgttttta
    30661 tagataataa aaagataaaa ataaagtttg gacaatttat ttcttcatat agcaaaatag
    30721 ctgaaagatg tggtaaagga gttagttatc aaatggttag aagttgtttg ttggttttta
    30781 aaaatgctgg ttttctaaca tacgaaacaa caaacaagta tatagtaata actattgaaa
    30841 actgggagct ttatcaagag aatatagaaa atcaacaacc taatcaacag actattaaca
    30901 atcagtcaac aacaatcaag aatataaaga atgaaaataa tattatatat agtgaaatca
    30961 taagcaaatt taactcaact tgtattgaac tttcaaaggt caagaaacta acagatacaa
    31021 gaaagaggag aataaattca agaataaaag aatatgataa agaaactgta ttagaggtta
    31081 taaatatagt tagtaaaaca agttttctga atggaaataa taatacagga tggaaagcaa
    31141 attttgattg gataatgaat tcaagtaatt ttactaagat actagaggga aattataata
    31201 gcaaggaaat tgtcataaat aaagagacag gaatatataa tccagatgac tcacaattaa
    31261 agtggtaagg aggttatatt ataaataatt caaacaactt aattaaaaat acagaagcag
    31321 agcaatcaat taaattacac taagttagtt ataaatcttt catatatttg ttttttaagt
    31381 atctctaata tcgtttaaat tacactaagt tagttgcaga tataccagaa aatatatata
    31441 aaattatgcg taaactatat tgttatgagt acaaataata tttacctatt cattaaaaaa
    31501 cttaactaag aatttaattt atattattga agtatcaata attttggaaa gtagaaaatt
    31561 ataccccaat aataccccaa ctacaaaaat agacaataaa aaataaccag aaaaattgct
    31621 tcaacatcat gaccaaatag ccatatacct atacttataa aaaccaacaa aacaatcaaa
    31681 taaccactta taaattctcc tcggtctcca ccattggaat ccacgaaaac atattgattt
    31741 aatagttaat atgtttttta ttttgaaaaa tcatatataa tataaattaa tagtttattt
    31801 aaaaatttca gtatgagcac aaaattatat aattattggg aattagttat aataagtaat
    31861 ttctagtaag aatgatttgc aaaaaataat aatttaaata caaaaaacta aaggatagaa
    31921 gtcataaaat taacttttaa cctttagtta tataaataaa aaattagtta ttactaaatt
    31981 aaaattagat ttttaaagaa cccaatatct ctattatcca tatcaccaat taacatgctt
    32041 ctatcaagta ataaattata ctcctcacag ctagtttcag gcaataaagt acatgaatgg
    32101 catgctccta gatttaaaga atttctacct tgaccagtac tatcaataca tattgggtca
    32161 ttagaacacc aaagagcacg attaagagca ctatttaata tagatggtaa tgaatcatgc
    32221 ataccttgcc taactaatcc tcctaaagta ccttcagagt caccacttgc agtgtaaact
    32281 aaaattccag acataacttt ttcattttcg gaattattac aatatatacg ttccctaagt
    32341 gaagaggtag catatccaca aacaaaacta agttctctta taattaaatg agctaaagta
    32401 tgtagtaata agaatttagg tgtaattttt ctataagctt tgtcattaac attaatatct
    32461 ttattatatc tagaatttaa aatagatgca ttatcctgta ttttaggatt agatgaaatc
    32521 cagcttttta ccatatcatt atttatctct atgaaaatac cttcacctct aacctcagat
    32581 gcaggataaa aagatttttt acaatctcta gatcttaaac ttataacctt agtatcatta
    32641 cagctatcat ctatatcttc ttcaccaaat atattattat caggtggatt gactctacta
    32701 aacccagtta atgcccttac ttctctaagt ctttttacta acactatttt actgaagttt
    32761 ggaatatcat aatcagatag attttgttct tctattgtaa agtcattagt ttttttagat
    32821 ttagcatcta tatttccaat taaagcctca tattcttctt ctctatattg atttctagtt
    32881 gttgttgatg gtgaagaatc ttcaaaaggc aataaatctt tcaaaactat ggatacttta
    32941 tcagtatcaa aacctgtttc tttagcaata tcactggcaa agtcctcaaa atcctcatcc
    33001 ataaagcgtt ctaacttatt ctttttaata gcacgatcta agaatttctt aaatgtatca
    33061 taacctttac tagatagcac tttagaatta agagtatcag agtatggtgg tataataatt
    33121 gaactttcta tcttaggata atatacatta gaggcacctc tttgagaagc aaatgaatat
    33181 ttagtgcatt tatttacttt tttattatac caaggcgaat taccagagca tttaaacatt
    33241 tccttatatt cactaggtac accataatca ttagatttag aagattttaa acgcataaat
    33301 gcgcccttca tattagcttt agctccacag ctacattcaa gttctatacc ttctaatcct
    33361 aggttacttt ttccagtctt cattaatatt tgaggatttt cacaaatttc ttttcttcca
    33421 gatttatttc taaaatgaac ccattttacc catggaaaat catcaatatg accatgttca
    33481 caaatagtaa ttataccagt aggtactaat tgtttagtag acttttttgt gctacaagta
    33541 aggcaaatag gtattttcat aggtttatct ttatgagcat ttttataaag tttctcccaa
    33601 tcttctatag gcataaattt tctacatttt ggacaaaagt accatctagg aaacctaaca
    33661 aaaggaacag aagatctatc atctatagtt ggaggtgttc ttagttcatt aaccctcaat
    33721 gtagcctgaa gcctatcatc ttgtatttta attgtattag tccaataatt tggatgagca
    33781 gtcattaatg tttgatcaat aaaatctagc atagctcctg gtccaaaaac acttgtagct
    33841 tgatttattc ttaaattatg agttttatca tctaatttta tagacatatt aattttcctc
    33901 caattctata atttcaacag tacattgttt atcaacattt ctcatagaat ttaatgtttg
    33961 tttttcattt gtaataacat ccttatcata aggaattaaa agattattat atattttatt
    34021 atcaaattta ctagggcgct tataataatg caataaatta tctttatcag atatttgagc
    34081 tttatcatgc cataaatcca ttataatatc taattcagat gaaatctcag atttaaattc
    34141 atttactata ttatcatcag cattttgatt attttctcta aatatatcga tagatctatc
    34201 tattatgaag ttttttaaat cttctacacc atccatattt tttgaaaatc gacttgcaag
    34261 atcattagct tgaagtccta aaatatgtct aatcatactt attaatactg catgcatgcc
    34321 tctttctcta gctggttcag agaaaggtgt aatactagta ggttcaacaa atttatagaa
    34381 tgattgatga taactaaaga actgttcata atgagatcta tctcttgttt ttgtaggatt
    34441 atataatgta aatataagtc cttcattact tctaccaact ctactgctag cttgtatgta
    34501 ttcagatgtt aacttaggct gaccaactac taccattaaa tttaatctat caacatcaac
    34561 accaactgaa atcatattac tagctaatag agtatcgaca gttaaattat tagaagtaag
    34621 agtattagat agttcatcta aagttgtatt tatcttagta gaagtaagtc tactagtaag
    34681 ctctctttgt tcatttaggt tccttaatga ttgataaggg tgggctgaga ctcttttaca
    34741 taatctttcc atgttgtctt ttatatcgtc atttaaaagt gtgctacact tacctaattc
    34801 tctgatacta ttaaaataag atactagtgt ccaatattta tccaataaat tcaactctac
    34861 attctccatc attttaagtc tttggagtaa tgctgacata agtctaacct ctacagtaac
    34921 ttgagttttt ccagatggaa taacacctac atatagtcgg ccacgttttt tacttaaagg
    34981 catctcttta acaaagaaag agttactaga tgttaatcct ggaggtggaa actgagctac
    35041 attacgatta tatagatttt taacttgatt ttgtgctttt cttatagtag cagtagaagc
    35101 tataatctta ggttttatac ccttatagct acacatagca tcaagtgcag tttcatataa
    35161 acctaccata gtacctaaag gtccagaaat aagatgaagc tcatcttgaa ttattaactc
    35221 aggagataag ttgctattat catcatctaa agcaaaaaga ctagctactt ctgtagtcca
    35281 agttatcatt gcaaatttat caactgtacc aaataaaagt gttggagggt tattataaat
    35341 ctcctcatct acaacttgta taggtaacat atcttcaaat gaacaatctt cttcaggaca
    35401 gcataagtag aatttcttag gtctagattt aattctatag ccccaatcac caacagcttt
    35461 tttagaagtt ttatcccatt ctttaacaag ttttgttcca caccaaggac attttagtaa
    35521 ttggaattta ttatattttg attttaaatt atctaactca tattcactat ttatactaga
    35581 tctaaactta atgttattac ctgttaagtt attaagcatt tcttctgcct catcattaaa
    35641 gtttggagtt tgatcactcc caatccacaa accaatagaa atctcttttt tcccaagttc
    35701 agacttattt tcttttctaa taatttcaca ggcacaaatt aatatacttg ctcttatgaa
    35761 ttgttgtgca gccaatagcc ttagtgtata tctcattatg atagctgtac cgttaccatt
    35821 ttctttgttt cttattcttc ttaagaagat agtaaaagca gatagaccta agtaggcctc
    35881 cgttttacct ccaccagtag ggatccaaag aaggtcaact aaatctctat gtttagagtc
    35941 aggattttct atcgaagata aacatgtaag tatataagca agctggaatg gtctccaagc
    36001 agaattatca tttgagtaat ctatatagtc aaggttatta gatccaggga gtctatccgt
    36061 aatatgtata gaatgacatc tttgcataag tatagctcta ttcattagag aaaatgctct
    36121 gtatacttca tcattagact taattaaatt tataccttct agcattctag acttagtatc
    36181 tctgcagttt tttatatgct catatgctac atctttaaaa acatcactaa gatcttttga
    36241 atcttcttct agatcatcta tccaaatatc ataagcatca acaaacttat aaagaaaata
    36301 tattttctta tctttactaa gatcagagat atctgataaa tttttcatag acagtaattc
    36361 tctagaaaca tcacttaatt catctacatt aaagtccaat ttaggtactt caaaatgagg
    36421 aataaactca gtacaaagtt ttattaaagc atcattttga atatcttgat ctatagctac
    36481 accatgacca gtagcaaaag tttttttatt tcggtaaagt aagtctaaag atatttcctc
    36541 agaatctaac tttttaaaag tatttactga tccagctgta aaaatatcta taaactctaa
    36601 atcattgtta tcttcagcta ataccattag ttcaggctgg aaaatagtat tattatattt
    36661 cttaggccca gattgactat taaccagcat acaagtaata ctaacaaagt catttgaata
    36721 aattctttta gataaaacta tatctaaatc tttagatata ggttttttaa tatagttttt
    36781 atccatatct attgatacta ttaagttttc atgtggaaca cgaacataac caccagtctt
    36841 attctcatca tcagggcatt ggttagctaa cttgtataaa acaaatttag cttcagcatt
    36901 atcaagtaaa tcatgctttt ttagtaaatt ataaaccttc tcagatgtta gtttttgctt
    36961 aagatatagg aatgatcccc taagttctac atattcatta attgtattgc tagaatagaa
    37021 gtcgtcacca gtatatttaa catgacagtc tgtatataaa gcatttctat aagtagcata
    37081 atttaccctg aaatttatta cttctgcatc tttttttagg aaaaaagtca tacccataga
    37141 agaaggtaaa gtttcattag acatacttat agctctatct agttcatttt gtgtatcatc
    37201 tgatgtaaat acattatctt caccatcata ttcagatgta ttacttacat caatattgtt
    37261 attaagtgga tataaaatac ctgttgaata acgctctatt ggactatctg ttattatttc
    37321 atattttata ttttcacaaa gatcttccga accaggtcca agaagttctt ttcttacaag
    37381 atctagggtt ttatctctta gttcactaca attcatattt acctcctatt tatttaataa
    37441 acactatata agtctaaaac tttgttaaca aggtggggtg acagatactt atcacaactg
    37501 tgtatttctc gtatttgtac aggtgtaaca taatcatttg tattcccaag catacttaaa
    37561 acaactgcag acacttcatc tttaattata tctgatttac tgctaaagaa attatcagat
    37621 acaaatgtat ctatagattt ttttatttta gtgtgcaaag agcgtatact tttagtagca
    37681 tcatatacct cggtatgatc taatttagaa tctataactt taaatatctt ttcgaaagtt
    37741 tttaaatata taggacctat taatctttta tttgttaccc agtttttgat tgttatagga
    37801 ttaatctttt cacctaaaac agctaaactg tttgatacat cattataatt atatttacta
    37861 taagatatat agtttttaag ttctgatttc catgaattag ttaatttata atcatcaaga
    37921 taatgagatg gcaataaatt aagttctaat agcttttgta taacattaat aactaattca
    37981 ccctcttcat ttaagtaatc atcaacaaat aaaaaccagt cattaacttt agcctctgaa
    38041 agtttctttt tcctaacact ttttttatcc caatctattg aataggctat tgcctttttt
    38101 gtacagaata tatactcatt attatcagaa atcatgaatg atgtaacatg ttctttttta
    38161 gagttgtaaa tcccttgatt tatagataga gataatataa tttcatttaa atttatatca
    38221 aatttataat tagatatata ttcatccata gaatcatcat cagaaatagg actatcggta
    38281 gaataagctt ctaatttatt ggtttcataa gttggtttaa aaggttttat atcaagtaag
    38341 ttatatattt tattattttt ttcaatttta tttcttgcag aatttatttg attcatatag
    38401 taattatatt tggataattc actattatat aaatacagtg taatatttat aatcaaatca
    38461 ctatttaaaa tatctaaata tttcaaatca tagaatccaa acataataag attttttatt
    38521 gtttttgaat ctttaaattt ttcagcagaa ataacttgta aatttatatt tctagatttt
    38581 aataaatttt taagtataat agcttcatat tgtttttgta gcaatataac aggtgtattt
    38641 ggtgtaaatg ttttgtattt atatgaagat actaatttat ttagtgtatt gaatttggta
    38701 ttattatcag ataattcatt tataattctt tcaaatttga ctataacatc atcaaataat
    38761 gcacttaatt ctaaatctgg gctagtactt gaaattaaat attttatatt ttctagcttc
    38821 gctgaaggag ttgctatatt taaatttaaa agctttatag tttcttctaa aaaatctagg
    38881 ttaaaaggtg tattttctaa gattttaaga agagagtaac tacacatcat aagtgagttt
    38941 tttatggaaa tatcaaaatc atacttagat atgtaataaa gtgattttct agcctgatgt
    39001 atcaagtcag agatattaga atcaacagaa gtagtacata tatttttatt tataagttta
    39061 tctagccata atttctgaaa agtagaggta ttttcaaaat cttggctata ggttaacaga
    39121 acatctttag accaagagta tatatttaga ttatctatat ttggtaaatc taatatattg
    39181 cttatatttg aatttgaggt tacaatattt acactttcta tcctttttct atttaaaatt
    39241 ctttcaaaat catttatatg cttataaatt ggataatcac ctattataaa tacatttttt
    39301 atagacttat cagatttaat aatttcaaat gcactagaaa tattagttgt aaatttaagt
    39361 aaaggtattt gcttagcgtg atttccagga taatcagttt cggcaccagt tgatgaaata
    39421 tatgaacatg gaaatagttc agtaaactta taagtattat taatatcttt tattttaata
    39481 ttactaacta agtcagatat atcatcttta caaggcaata taatcagtgt agaatcattt
    39541 attactccag tcatattttt taagtctgaa aaacctaaag atgatagaac attctttgtt
    39601 tgaaaagtct tagatgctgg agttttgccc atagaattga cttctaaatg accattatag
    39661 gttataagca tataagccga gtcaataggt ataagtgttg tatccgtttt atttttatgt
    39721 cctaaagtta tgtgtgtatt atttatattt ttaaatataa ctatttgacc cttgtagagc
    39781 aggggcatac ctttatcgag ttttgtaaga atgtgattat ttgggtttaa tgtattattt
    39841 aagtatgagt ttatagctat attcaacaaa taaatagcat atatgtattt gtcattataa
    39901 ttgataatta agttattatt tttttcattt ataatataat ttaatacatt aatattatct
    39961 tgataatact tagaatttgt tagcctttgt ttattaaaat aaatttcaca tatatcatta
    40021 tcaagaatat aatggatatt tgtagttaac atttaaatct cctttagtag ttactattgt
//
LOCUS       DAMJVG010000033        39998 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.033, whole genome shotgun sequence.
ACCESSION   DAMJVG010000033 DAMJVG010000000
VERSION     DAMJVG010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 39998)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39998)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39998
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.033"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            343..1203
                     /locus_tag="PC512_001824"
     CDS             343..1203
                     /locus_tag="PC512_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDF2441567.1"
                     /translation="MKKQKSPILLEMLGLFFGCISMSIGINMFLKPHTIAPGGLSGLS
                     LVLNKVTGLPVSAIMLIIGVPLVILAFRIMGTKNSLKTLFGTVVFSAIVQLTDPLSKL
                     RFTNDLLLSSIAGGILVGIGLGIMFKSDASTGGTDLIALILSKKFPGIKATKFMSCLD
                     GMVVISSGIVNRSLETALYSGIALCVLIKIADMIMEGFDHSKAFFIISDEPESLRQAI
                     TEELDRGLTILDGKGGYTRENKEVLLVVVSKKQELYLKRLVKRTDPTAFVIVTDVHEV
                     LGEGFKNLEN"
     gene            complement(1442..1999)
                     /locus_tag="PC512_001825"
     CDS             complement(1442..1999)
                     /locus_tag="PC512_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2441568.1"
                     /translation="MSDSEYPQMKTLETRNCILRPASLDDVEDFFDCYKNKIVVKHLP
                     FSEHKSLEDTRKFIKSFFLNPYKKGKIGHFAIVYKRDNKVIGNMGFNNINPKALEAEI
                     GICINPSYWGHDFATEITKRVIQYGFRELNLNKIIAITYEENQNSTKSLDLLGFKCTG
                     KYIKKIHTGNTVKNVPCYQYELKKQ"
     gene            complement(2189..3076)
                     /locus_tag="PC512_001826"
     CDS             complement(2189..3076)
                     /locus_tag="PC512_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF2441569.1"
                     /translation="MNIKLELYKVFNAVVNNKSFSLAAKELFMSQPAVSQSIKQLEEQ
                     LDTLLFYRNNKGVKLTPEGKILSEHVTTALKLISSGEDRINKFKKLEYGSLKIGVGDT
                     AARFFLLKYLEIFHKKYPHIHVSTINRTSRELISLLKDGNIDIAIINMPIEDDTLNIV
                     ECIEIHDIFVCANDYIEYKGRKISLEELNTLPLIMLENKANSRLYVNEYFLSKGIKLN
                     PDIELGSHELLLEFAYINLGVSCVIEEFSIDYLENEKLFKLDIKEPIPKRNIGYCHLK
                     DISLSLATKEFLSMISNNI"
     gene            3195..4394
                     /locus_tag="PC512_001827"
     CDS             3195..4394
                     /locus_tag="PC512_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003493023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coenzyme F420-0:L-glutamate ligase"
                     /protein_id="HDF2441570.1"
                     /translation="MDRLVGTVSRGVRAPIIRQGDDLVKIVVDSVLNASKSENFEVRD
                     KDVIAVTEAVVARAQGNYAHVDNIAKDVKDKFGDDTVGVIFPILSRNRFAICLKGIAK
                     GCRKVVLMLSYPSDEVGNHLISIDELDDKGINPWSDVLTEEKYRELFGYNKHTFTGVD
                     YVDYYKNLIKDCGAEVEIVFANNPKTILNYTTSILTCDIHTRQRTKRILRQNGAKKVY
                     SLDDIMTASVDGSGYNDQYGLLGSNKATEETVKLFPINCDEVVNKIQGNIKEITGKDV
                     EVMVYGDGAFKDPVGKIWELADPVVSPAYTKGLEGTPNEVKLKYLADNDFADLSGDEL
                     KEAISKYIVEKDNKSDDLTGNMVSQGTTPRRLTDLIGSLADLTSGSGDKGTPIIYIQG
                     YFDNYTK"
     gene            complement(4588..7143)
                     /locus_tag="PC512_001828"
     CDS             complement(4588..7143)
                     /locus_tag="PC512_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDF2441571.1"
                     /translation="MMSLVKFSIQYIKHYKKQSISIVLSIVLSVALLTGIGSLVHSAD
                     KSRIEKIREDSGDYHYFYKVDKEQLNKIKENKKSKEYTVDRLGVTKPKNQIDEPFIIE
                     FLNADSSYLDMTGRKLLKGTLPSKDGEIVLDTYSLNNLNVNKEIGTEINLDGKIYKLC
                     GILSSLSNPETALEGFVNDYFQPKEKDSYIVYVKYDENKNIKKQNYKFMKKFNISKEK
                     TYINWSLSVEFGVKPPKNIEKYNIFEFLKNLELNTNAIILLVGVFGAAAVYSIFHVSI
                     LQRISQYGVLEVLGANNKQLLFLLFLELFLLFIVGFPIGCFLGIGVASTIYEQFPHIF
                     LSSDIVPGAFFISEKSIYLGFLFILLLLILIAVRVVHQLNKYSSIESMKNFKITNKKK
                     RILESVKHSNMTKVLSHKYMTQKKGMFIGILFSLSLGGIIFLCSSYSIQLTKNNNELT
                     MKADDGLNSDYQITMQTTDFDVGIPKDKISRLNNVEGISKVYPVRYLFGAMQIKEEQL
                     FWKNFFKPLEKDYRIKTFFDGICTKQNEGGYLLKTNIYGYNNGMLEGLNSYIIDGEIN
                     THDMVKNNKVIVRLPMDGTGMYDAVDINPGDTIKVKVPKTMKPTDEIVKFKEENKNDY
                     TTKEFVVAATVKRVMANNIYFIGDYGMDIVMTNGQMKNNFDIENYNSVSIKKTEDSNS
                     EELSENIKSVVSDVKRCIVTDYTIAIEKNNTYLNQKLLFIYGIVFVLLAISLFHIINT
                     VSYLIFSRRHEFGILRAMGITDNKFLLMMIREGFLYGFYASIIMVIGSVIGQFMIYFM
                     VKRVYLYINPILKINTPLYIGMIILNITISIVAVIIPVRQILKSDIISEINKN"
     gene            complement(7140..7826)
                     /locus_tag="PC512_001829"
     CDS             complement(7140..7826)
                     /locus_tag="PC512_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2441572.1"
                     /translation="MSILVTNNLVKHYGKGETKVKALNGVSIEIERDTFTAIVGTSGS
                     GKSTLLNIIGGLDNPTSGDVIIKGKNISKIGKKDLTVFRRRNIGFIFQNYSLMPVLNT
                     YDNIALPVTLDKGNHIDHEYIEMLMKTLGIWDKRLKFPSELSGGQQQRVAIARALANK
                     PALILADEPTGNLDSKTTMEVVCLLKESSAKFHQTILMVTHNENIAQVCDSIIHIEDG
                     VVVNTGGELL"
     gene            complement(7903..8811)
                     /locus_tag="PC512_001830"
     CDS             complement(7903..8811)
                     /locus_tag="PC512_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2441573.1"
                     /translation="MFILAFIICTVVIFIVSTKINRKRYDELNLMLNQILEGKEVTYP
                     DTKDTRASKISHQVKKIKDMIEIEVEQSKSEKEAIKGLISNMSHQLKTPLSNITIYCE
                     LLENINISTLQKKEFLQKMKNETFKIDWLLQSLFKMTKLEDGVIEFEVEELLIKDTLI
                     QSISTIFNKAEAKNIRINLEPFSDIKLVHNKKWTIEAIVNVLENAIKYSPSDSTITIS
                     VIKMELYTKITIKDEGIGIDSRELNDIFKRFYRSKNVENQNGTGIGLYLTRLILEKEN
                     GNIIVESKLGSGCCFSIFLQNCKSLN"
     gene            complement(8813..9484)
                     /locus_tag="PC512_001831"
     CDS             complement(8813..9484)
                     /locus_tag="PC512_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2441574.1"
                     /translation="MNLLIIEDDINLNEGLFYAFENDGFNVFKAYTKQEGLNIFNSKN
                     IDFIILDCNLPDGDGFDVCQIIREKSDIPIIMLTARDSEIDEVKGLEIGLDDYITKPF
                     SLSVLKARVKVAIRKKSNNKVIYSNGIKLDQKLLKVYKNKECLELSSVEYKLLSYLIE
                     NKGQILLKEQILHHIWDSEENYVDDNIVSVNIRRLRVKVEDDPSNPKYIKTAYGMGYL
                     WNEVE"
     gene            9746..10810
                     /locus_tag="PC512_001832"
     CDS             9746..10810
                     /locus_tag="PC512_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S ferredoxin"
                     /protein_id="HDF2441575.1"
                     /translation="MKRVDERNTMFARANYKKDSTAYNDYYKKNPDKKEIDDSIRNRP
                     NLCSEGTMTYNELNSPMASSAFDFLSDIKSLCEGKVSDTKVDVDAKSMTKKIKGLAKQ
                     YGASVVGITKLKDYHIYTNRGRHEENYGEEINLTHKYAIVFGCEMDKEMINRAPMICE
                     VIETSKCYVDASIVGMILSYYIRNLGYDARNHMDANYLVMPVFIARDAGLGDIGRNAI
                     LTNKDYGSRLRLGVVTTDIPLLEDEYVDFGLEDFCKVCKKCSFNCPSHSLSNDIKIGD
                     DGKYNWVIEHETCYIKWRYLGTDCGMCISACPFSQNLETIKNTTSFKGNNELIQKALD
                     EYTSKFGKRIFIPGNPSWLK"
     gene            10968..11654
                     /locus_tag="PC512_001833"
     CDS             10968..11654
                     /locus_tag="PC512_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2441576.1"
                     /translation="MEKILVVEDDSILNKTLSYNLIEDGYIITSKFTAKSALKSIFEC
                     EFDLIILDINLPDKSGFELCNEIKENYNIPIIFLTANDMECDMIKGYELGALDYITKP
                     FNINIFKQKIKAFLNHLTIKTKQDYYKDGYLEINFSELSANINGNQIIFTPLEYRTLK
                     LLTENPKSILTRKVLLEKLWDIDANFVDEHTLTSVISRIRSKIEKDNLKYIKTVYGMG
                     YMWLGERNEF"
     gene            11644..12675
                     /locus_tag="PC512_001834"
     CDS             11644..12675
                     /locus_tag="PC512_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2441577.1"
                     /translation="MNFKKFSFSSIYLIIAVGIIFTAILFSISIYLITGDLKLIALLL
                     IYTMVLCGFIALIIFLLHKKIVIFCSKICHTLDSMMNSEDNIEIELEEETILSRINHR
                     LIRMYEVIQENRNSIAIEKADLQELVSDISHQIKTPIANLKMINTTLLNQTFKTEIQK
                     DFLMDMENQLDKLDFLMQSMVKTSRLETGIITLSKKKNSIYETIATALSGILFDAEKK
                     NIEVTVDCDPNLYIIHDKKWTSEAIFNILDNAVKYTSSNGKIRVATECWVMYTKIDII
                     DNGKGISESRQAEIFKRFYREEDVHDIEGIGIGLYLSRKIISLQGGYIKVTSDIGKGS
                     TFSIFLPNK"
     gene            12757..13422
                     /locus_tag="PC512_001835"
     CDS             12757..13422
                     /locus_tag="PC512_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2441578.1"
                     /translation="MSILQVINLKKYYGQSSNITKALDGVTLSIEKGEFISIVGTSGS
                     GKSTLLNMMGGLDNPTSGKVIIKGKELSTMSDEQLTIFRRRNIGFIFQNYNLVPLLNV
                     YENIILPIGLDGETIDKDFINEIINMLSLEEKLYDIPSNLSGGQQQRVAIARALVTKP
                     AIILADEPTGNLDSRTSSDVLSLLKVTSKKFNQTIVMITHNNEIAQLTDRIIRIEDGK
                     IVN"
     gene            13435..15852
                     /locus_tag="PC512_001836"
     CDS             13435..15852
                     /locus_tag="PC512_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2441579.1"
                     /translation="MFRNNNRTFIRKIALNDLKINKLKTYLSGIIIMISTCLLLTVTL
                     VSYNASVDLVNASPYHAIYKSVDEKAKNILYKNKNFSGVGTYKLIGSNKKTDCIMSIV
                     YADDTAIKLMNFQPLKGKLPTNKNEIAISEKYLQEFGLDKDIGDSIKLNYYDDITNKE
                     VQCDFIIVGFLENYYQDNAKQYYTVVSNDYFKNIASTPLQNKSNTFDESRPDTVDVLV
                     KLSEENTEKDSASIKTQLNKIGLSLGIKKYNIYLNDNYIESNLIDGEQIITVLVVGIV
                     VLFSSVFVIYSIFYISVVNSVQMYAKLKSLGMTSFQLKKIISLQGNILSIIFIPLGVI
                     ASCIIAYIIQPLAWQMIADLFIILILSLVMFLTVRISLFKPARIISKISAIEAMQYTE
                     TKFRKKAKNFSYINIKNLALKNIESNRKKNLIALISLSISGVLFISIANLANSIDFKK
                     QLSQQFVYNEDYIISIKSDNLYEHITEIQQNNPLTDSLKNEIKSIHGVKKLIESKSIK
                     SNIIEPYIKDRDEKQFITLIKGITPELSKSLEEYIVSGKIDYTHLDSDSLIINKYRTK
                     YYGLNLKVGDTVTFNIFSGNDIIKKKMKIIGIIDNSNTGGMFFASDKTLESLTPYNTN
                     LDFSILIDKKHSKEVEEKLLSIIQKNSNLMLYSYEDDYRMITRAFQYIIIASYIFVGL
                     ISCFGILNMTNTLINSVLIRKKEFALLQAVGMTRKQLRNMLYREGLNISIKAICTSST
                     LGYFGSNLLCTFIKDVIRLDFINFKFSIFTILIFSFVLIGIQVLVTELLVRNIEKKSL
                     TERLRSQ"
     gene            complement(16033..16824)
                     /locus_tag="PC512_001837"
     CDS             complement(16033..16824)
                     /locus_tag="PC512_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDF2441580.1"
                     /translation="METKQYLIDFYNTYDEDSRLALKHGMVEFLTTMHYIDKYIKSGD
                     CVLEIGAATGRYSHTLARQGYDVDAVELVEHNIEVFHKNTQSNENISITQGNAMDLSV
                     FPDNKYDITLLLGPLYHLYNKEDKQQALHEAIRVTKPGGVVFAAYVISDGCLIDEGFH
                     RGNINVSEYIEKGLIDPQTFAAKSEPKDLFELVRKENIDDLMSAFNVTRLHYVASDGL
                     ALYMREAVDSMDDDAFALYLKYHLATCEREDLVGVTSHAIDIFRK"
     gene            complement(16857..17444)
                     /locus_tag="PC512_001838"
     CDS             complement(16857..17444)
                     /locus_tag="PC512_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2441581.1"
                     /translation="MPPKVKITKEMILNTVLDITREVGFEAVNARSIASKLQCSTRPI
                     FTCYENMNELKNEFLAFAYEYYNQYVVNYSNSKSVSPYLLLPLSYIEFAQEETHLFKL
                     LFINDLDLMMEEANDFYKEIDNEKKARLFSESIGIELECAKVIFLDLFLYTHGIAVLT
                     ATKKLTLDRYSAEKMLKNILTAFIRQEKPDWNLSI"
     gene            complement(17621..19012)
                     /locus_tag="PC512_001839"
     CDS             complement(17621..19012)
                     /locus_tag="PC512_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="benzoate/H(+) symporter BenE family transporter"
                     /protein_id="HDF2441582.1"
                     /translation="MERLARREQPHIKFGMFKIRIPFIHYRFEKPEAIQGIISSMTSL
                     GTIGLSTQILGLPYEVAWSMAIINSILYCLHVFMGDPVVPGWITASITLTTAYLLKFS
                     MGIERIQALTALQIDLGIIFILMGITGVAGKLVSKIPNSIKGGILMGVGISTIISEFN
                     PKGRFDSYPISITVGILVACFVMFSERFDTLKVKNKFLFHLGEYGVVSAILVSLIVGI
                     FSKEIEIPRFSFDNLVYIVDFKNLINTVSPFGIGFPSVMLFIQGIPMAFMIYIIAFGD
                     FITGENLVLSESENRKDEYIDFNSNRSNVISGIRNIFMAIFSPYIPMCGPLAATLTGS
                     VAQRYKVGKEAMQSVFSGMGTLVWVSAIFICFYPIAQIATPLIPLALSVTLLVQGYLC
                     TKLSMELCNTGVEKGLIGLMGGVIAAKGGTWGLAVGFILYFILIDSKKRKEKDINSIE
                     DCVYEILDKKKSI"
     gene            complement(19202..20500)
                     /locus_tag="PC512_001840"
     CDS             complement(19202..20500)
                     /locus_tag="PC512_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase/BAAT N-terminal
                     domain-containing protein"
                     /protein_id="HDF2441583.1"
                     /translation="MKVNVYNVESFVDERLKIMVSDLIPNTKLKISVKMEFPWCKGEE
                     FSSYGVFCSNEKGEVDLDLVEPIEGTYKADNCMGLIYSLEKSKTEGKNFAENISIDKP
                     IIMNMIFETSIERKEVELKRIFKSEDITTKYISDEFIGKLFYKQNSNNKTILMLGGSD
                     GNLDALDLLAAPLASRGFNVLTVAYFALEGLPDKLEEVPLEYFEKVFEWISENEITST
                     KEIFVHGTSKGGELAFLLASRYEQIKKVVVSQPHIYCFQALNGLMSGNDTSSWSYKGE
                     PFPYIKVDNDIFFEEQKKNISKDIPFGFNSTYKKSLKRAENRKEARIKIENSKADILM
                     IAGKEDNIWNSYEACLEALEIFEENNYPYNVELLTYNNMGYPLPIPYIMPLKETLCMS
                     MSRGIFSSGGTVEGNSKGQFESWNRTIEFYKKPLSSDLNN"
     gene            complement(20857..21732)
                     /locus_tag="PC512_001841"
     CDS             complement(20857..21732)
                     /locus_tag="PC512_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HDF2441584.1"
                     /translation="MITFDVNGAIIRFDDTKNNYNKIRKIFKLYALEISKNFERDCLN
                     SFQNLKQISDRGLSLGEKYIEESFKKGIETIVSFGIITIDIDTFKSVYCEKYLDFKRL
                     FNNLNKTFIIPNKNKKNGHASFLEIESTIKKMSNYLYNDCFKIHYAVVDALIENRITA
                     VHSYIDEESIKKSNALFNNYKDGFIGKADECKVVKQIITLNPYREDVYEFLVKEDGDF
                     SKEIERLTEFLGYDIREYKASLMDIYINELMESDENDVENAKEKIEKYARYIGCSDEN
                     LYVARVNAIYTFANA"
     gene            complement(21925..22611)
                     /locus_tag="PC512_001842"
     CDS             complement(21925..22611)
                     /locus_tag="PC512_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HDF2441585.1"
                     /translation="MFGVIANSLAIAGGCIVGLIIKGGLPQRVSDTIMNGIALCVLYI
                     GISGALEGKNTLVTIISVAVGALIGELIDIDKWVNKLGAFLQSKFSKGNKKDSIAEGF
                     ISSSLLFCIGAMAVVGSLESGLTGSHDTLFVKSVIDGIASIIFTASLGIGVMFSAISV
                     FLYEGIICVGASFLNGFLSDPVVTEMTAAGSLLIIGLGLNVLKLTNIKVANLLPAIFI
                     PILFGVFGII"
     gene            complement(22660..23193)
                     /locus_tag="PC512_001843"
     CDS             complement(22660..23193)
                     /locus_tag="PC512_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HDF2441586.1"
                     /translation="MSDLNNKKEQDENESSMNETKIYDILDKLNVEYDVVEHEAVYTA
                     EQLVILDGITKGCQCKNLFLRNAKGNKYYLIVVKGEKQVDLNSLKDKIGSSRLSFASP
                     ERLYNVLKLLPGSVNPFSLINDTERKVELYIDKDVIKEDYLNFHPNINTKTVNISRKG
                     FEEFLEYLKYPIQSIDV"
     gene            complement(23237..23869)
                     /locus_tag="PC512_001844"
     CDS             complement(23237..23869)
                     /locus_tag="PC512_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclase family protein"
                     /protein_id="HDF2441587.1"
                     /translation="MKVFDLTHVTHNDMPVYAEPNRPDIKKVAIIEENGYQETLISVF
                     SHNGTHMDSPRHMYTKGETLDKLDIENFVGKAYVLELEKGNENIELEYLKKYEDEIKN
                     SDFIIFKSGWSKFWDKKQYYVGYPTLTKEAANYIANTNIKGIGIDMLSVDRYDTSVFE
                     VHHILFEKGKIIIENLTNLENVPEKFLFIAAPFKYNDADGAPVRAIAIVE"
     gene            complement(23959..25038)
                     /locus_tag="PC512_001845"
     CDS             complement(23959..25038)
                     /locus_tag="PC512_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HDF2441588.1"
                     /translation="MKIAIFLGAGASAAENLPIQNELFSEYFKKLNPTNYNTKMNREL
                     YIFFKQMFNIDIVKDNIDNANFPTFEEVLGLLDLAEQRKEAFRNFGLENLNNRSDSIR
                     FLRQYLILLMAEAIHNTPRTDNKYHKLLVENLLENDLLLDTTFISANYDIHIDNTVTG
                     LRDKNDLPIMLDYGVEFTNFKEELNWRKPKEPLIKLYKIHGSLNWLYCPICNSVTLTP
                     HEGGVMKLIENSSETKCLECGELTEPIIVPPTYFKNMSNIFLSNVWNETEKTLRDTDL
                     LIFCGYSFPEADMHIKYMLKRVQTNRKKPPLKIMVFNNHSQKQRITLKKEEGRYKRFL
                     GEDVIFTDNSFQDFSVNPLRFIKNI"
     gene            complement(25171..26517)
                     /gene="pepV"
                     /locus_tag="PC512_001846"
     CDS             complement(25171..26517)
                     /gene="pepV"
                     /locus_tag="PC512_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HDF2441589.1"
                     /translation="MKEQIKEKVNSLQDEMISSIQESVKIPSVISEATENCPFGENVD
                     KALRGILDLCKSLGFKTVYKDGYYGYAEIGQGEKMIGILGHVDVVPEGDLESWNYPPF
                     EAVLEDGKLYGRGTQDDKGPTISAIYAVKALMDLNVDFNKRIRFIFGADEENLWRCIN
                     KYKENNEEIPNYGFTPDSRFPITNAEKGLLQVHLTCDSKSDIELSVGKALNAVPGKAI
                     YIGKYSDKLKKELDKLNFEYTVEGNKICIIGKSVHSAASDTGINAVARLCIALNNIGI
                     DSNIIKFLAEVIGEDANGNNIIPNCKDDVSGKLTVNIGRVTIDNEKEFAGIDVRIPVT
                     YKKDDFVKELKKMTDKYNLNYEEYDFLDSIYVPEDTLLVKTLRKVYEEETGLDGTPLS
                     SGGATYARALDNCVAFGAIFPGKPETEHQANEYLIVEDIIKATQIYALSIYELLKI"
     gene            complement(26586..27866)
                     /locus_tag="PC512_001847"
     CDS             complement(26586..27866)
                     /locus_tag="PC512_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine gamma-lyase family protein"
                     /protein_id="HDF2441590.1"
                     /translation="MLNETKELLKDYYGIDDDTFKLSQEIMEEIKDKFEEIKEIREYN
                     QYKVLKAMQESKLSDMHFNWTTGYGYNDIGREKIEEIYSKVFNTEDALVRPIIVNGTH
                     ALTLCIQGIVRPGDEILSVTGRPYDTLEGVIGIREEKGSLKEYGVTYDDVDFLEDGNL
                     DLEGIKNKINDRTKLVMIQRSKGYSWRKSLSISDIKEAIEVIKSVKPEAIVMVDNCYG
                     EFLDTKEPTDVGADVMAGSLIKNPGGGLALTGGYIAGRKDLIELISYRMTSPGIGKEC
                     GLTFGTTRNVLQGFFLAPYIVSQAVMGAIFCSRAFEKLGYDVLPKYDDLRSDIIQCIR
                     LNNADEVISFCEGIQEAAPVDSYVKPVPWDMPGYESEVIMAAGAFIQGSSIELSADAP
                     IRPPYNVYFQGGLTFDHSKMGTLKAIEFIKKLKK"
     gene            complement(27993..28253)
                     /gene="hfq"
                     /locus_tag="PC512_001848"
     CDS             complement(27993..28253)
                     /gene="hfq"
                     /locus_tag="PC512_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone Hfq"
                     /protein_id="HDF2441591.1"
                     /translation="MKNTVLNLQDLFLNNARKERIPVTIYLVNGVQVKGLVKGFDSYI
                     ILIEGDNRQQNMIYKHAVSTIQPGKYINLTNQNQNNNNNNNR"
     gene            complement(28367..29302)
                     /gene="miaA"
                     /locus_tag="PC512_001849"
     CDS             complement(28367..29302)
                     /gene="miaA"
                     /locus_tag="PC512_001849"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HDF2441592.1"
                     /translation="MKKIPLIILTGPTAVGKTDLSIKLAKDMNAEIISADSMQIYEYM
                     DIGSAKVTEEEMQGVKHYLIDEVKPDYPFSVSEFQQRAKKYIHEINEKEKCVLVTGGT
                     GLYLNSLIYNMDFAQSDANNELREELQKQLAEKGIDYMHNKLKELDEESANRIHKNNT
                     KRVIRALEVCLSGKKMNDFSSDLKFNEEYQPIIIVLNRDREHLYQRINMRVDIMIKNG
                     LVEEAKKLLSMGFKKDMISMQGIGYKEILKYLDGEYTYEEAIEIIKRDSRRYAKRQIT
                     WFKRYKTAKWFDLDQYENIDELKNEIILYIKDSIK"
     gene            complement(29340..31307)
                     /gene="mutL"
                     /locus_tag="PC512_001850"
     CDS             complement(29340..31307)
                     /gene="mutL"
                     /locus_tag="PC512_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HDF2441593.1"
                     /translation="MKNIINILDDLTINKIAAGEVVERPSSVVKELIENSIDAGANKI
                     SIDIIDGGKSLIKITDNGIGIPSSEVEKSFLRHATSKIKKIDDLYDLYSLGFRGEALA
                     SISAVSKLEMTTKTKDEIIGTKIYVEGGKIISKEPIGSTNGTTIIIKDIFFNTPARQK
                     FLKSTHAETINISDLINKLAIGNPNIQFKYTNNNKQMLNTPGDGKLVNTIRSIYGKEI
                     TENIIDVEFKCNHFKMNGYIGNNNIYRSNKNLQHIYINKRFVKSKIIIDAITESYKSI
                     IPIGKHAVCFLNIEVDPSCIDVNIHPNKLEIKFEKEQEVYIELRDFLKVKLIHSNLIG
                     KYATYSDKKTQPRIAINSREKSTDYKLRNNDLLESTPKNSNITKGKDEVIEVVTLSSE
                     KPINEFQSVSEVLNASVEDDVKNINYLSEDSANDNIQEEFQVDGIKNEGNYYLGDSIK
                     DSEEEYLCSSKRKFSLYGYFVIGVVFNTYIILSKDDSMYLLDQHAAHERILYERYMEK
                     FYRQDINMQILLDPVVIEVSNIDMLQIENNLELFMKFGFELEIFGNNHIMVRCVPTIF
                     GVPETEKFILQIIDNIEEITSNYDLKGERFASMACRSAIKANDKIYDIEIKSLLEQLE
                     KCENPFTCPHGRPIMVEISKTEIEKMFKRIM"
     gene            complement(31318..34161)
                     /gene="mutS"
                     /locus_tag="PC512_001851"
     CDS             complement(31318..34161)
                     /gene="mutS"
                     /locus_tag="PC512_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HDF2441594.1"
                     /translation="MQIDMNKLTPMMKQYLEVKNRYKDCILFFRLGDFYEMFFEDALV
                     ASKALEIALTGKACGLEERAPMCGVPFHSANSYISKLVENGYKVAIGEQMEDPSTAKG
                     IVRREVIRVITPGTVLDGNLLENKKNNYLLSLYKDGTNIGLTYVDISTGETNATCLNE
                     DKVIEEIAKIHPTEIIINDLDFIEKLRDIATVSNIYINESFSDNYLDINILKEYFPDV
                     YLQKLKFDDKGLIKSSLSILLNYIYNTQKQITSNINNINIYNSSEYMVLDMFTRTNLE
                     LTQTIRGNKKKGSLLHVLDKTSTAMGGRLLRKYVEEPLINKSKIENRLDVIEEIKDDF
                     ILREDLNDILKNIYDIERICGKIAFERVTPKELIHLKNSIEKLPNLKDTINLSNAKIL
                     KEYVSEMDKLDDIYNLIDEAILEEPTITIKDGNIIKSDFSDELKELREISKNGAFLVK
                     EIENREREKTGVKSLKIGFNKVFGYYIEITKANFKQAKLDETYIRKQTLSNAERYITP
                     ELKEIEEKILHAEEKIKSLEYEIFVEIRDTIYKNIDRIQKVAKTIANIDVFVSLATVA
                     HINNYVKPAINENNKLDIRNGRHPVVENIVGEENFVPNDTYLNRGENIINIITGPNMS
                     GKSTYMRQTAIIALMAHIGSFVPAESADIPILDRIFTRVGASDDLSQGQSTFMVEMNE
                     VSLILKNATERSLVILDEIGRGTSTYDGISLAWSIVEYIQKNIRCKTLFATHYHELTD
                     LEEEFKEVKNYSIAVKEDGEGIIFLRKIIPQGADKSYGIYVAKLAKLPDEVIERAKYI
                     LKDLEKNHVYNSVAINGDKENNNIINSNLDEELVKVNQSNFKNKYESLKIEHELIVKD
                     YKHIKKDYDKLNSKFKALNDEVALMKQNDDKEKINQEDSVKEVALTQISFDSVNRDIL
                     SEEILNLDILNMTPLDAINSLYNLQRKAKEIKS"
     gene            complement(34322..35056)
                     /locus_tag="PC512_001852"
     CDS             complement(34322..35056)
                     /locus_tag="PC512_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2441595.1"
                     /translation="MLTQMNFYHNKKVKVSIENVSKTYKDIEVLKDISIDVYEGEFVS
                     ILGPSGCGKSTIFNIITKLTDYDSGKVNINGKYSYMYQKDLLLPYKTIIDNVSLPLIL
                     KKEKKSKARSMVKPYFEVFGLSGYEDKYPSELSGGMRQRANFLRTFINSNDIMLLDEP
                     FGALDSLTKTSMQKWLLDVKKKVNSTILLITHDIDEAIMLSNRIYVISKKPSIVKKEF
                     VIDSRKLNEDNLENIIKLKKEIISLL"
     gene            complement(35025..36038)
                     /locus_tag="PC512_001853"
     CDS             complement(35025..36038)
                     /locus_tag="PC512_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2441596.1"
                     /translation="MNFKKLGILGLVSVFTLATITGCSSNNNKDKNNDKDTSSKKVTM
                     VLDWTPNTNHTGLFVALDKGYYKEEGLDVEIVQPPESGAETLVATGKADFGISYQEQV
                     TYAKTSEDPLPIKAVATVIQHNTSGFASPKEKNITTAKDFEGKTYGGWGSPSEEAVFK
                     AVMKKNGADFNKLKIVNTGQDDFFAAMKTVDFAWIFEGWDAVKADLIGYDLNFIPVKD
                     LDERLDYYTPLIISNETVLKNNPELAKKFLKATTKGYEYAIKNPEESAKILVKHAPEV
                     DEKLALKSQEYLASKYKDDAPRWGEMKDSVWNNYTSFLKEYKLIDKDMKASDAYTNEF
                     LPQ"
     gene            complement(36060..36830)
                     /locus_tag="PC512_001854"
     CDS             complement(36060..36830)
                     /locus_tag="PC512_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2441597.1"
                     /translation="MKNLEIIDKVKDSIYPIATFLFILILWQSMVGVLEVPQYILPTP
                     VDIINVFFKDYQNLSIHAVVTIGEAILGFIVAIIISLVIGILMDFVSIIKKCLYPIML
                     VTQMIPTIIIAPLFMIWFGFGTMPKVLMVMLTCFFPILISFVDGIENIDKDYLNLFKT
                     MDSNKVNTFIHLKFPMAMDKFFSGLKISATYAVMAATVAEWLGGTKGLGVYMLRSKSA
                     YALDKVFASTILVVIFSLMFVGIVQAVKKVVIRHRLID"
     gene            complement(36805..37095)
                     /locus_tag="PC512_001855"
     CDS             complement(36805..37095)
                     /locus_tag="PC512_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MTH1187 family thiamine-binding protein"
                     /protein_id="HDF2441598.1"
                     /translation="MVIADIAVMPLRPYKGEEEMYKVVDACIAEIEKSGLKCEIGAMS
                     TTVEGDFDEVFELLKKVHKIPFNLGCERVITVARVDEKAGGLTIDEKLRNHR"
     regulatory      complement(37226..37325)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     regulatory      37945..38034
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            38087..38263
                     /locus_tag="PC512_001856"
     CDS             38087..38263
                     /locus_tag="PC512_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441599.1"
                     /translation="MFMDKMDRCTHILTAYICSSRDYCNFIDTQLNDFILEYGENVVE
                     SCLHQVMVLVSRYN"
     gene            complement(38378..38734)
                     /locus_tag="PC512_001857"
     CDS             complement(38378..38734)
                     /locus_tag="PC512_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2441600.1"
                     /translation="MDIDNNFEEFPNIEERQKDFNCSIGFTMTVIGSKWRAIILWHIL
                     KQEPIRYSQLKKEVVHISHKILSQELKYLERDGLIKRISYPTIPPKVEYLSTKRGKSL
                     ESILLELCNWGKQYMR"
     gene            38990..39903
                     /locus_tag="PC512_001858"
                     /pseudo
     CDS             38990..39903
                     /locus_tag="PC512_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007061260.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family isomerase"
BASE COUNT        13630 a         6213 c         4647 g        15508 t
ORIGIN      
        1 taataaatcc ttttgataac atataaaagt aagataaatt tttccattaa ataccttata
       61 attatacaca aaatctctat atacgttaaa cagtatagag aaaattttca tagaaccatc
      121 tttatagggg atactttata aaagaataaa aaaattataa tatataaaaa cttcatagga
      181 gagtaacaac atcagtaaaa atatgaaaac actatataaa aattcaaaaa tattaagaat
      241 aatgaaatac ttgaaattgc ttatatcaag aaattttata taatataaac tggtcaaata
      301 tgttataata ttaaattgtg acaagttcat ggaggtgttt atatgaaaaa acaaaagtcg
      361 ccaattttac ttgaaatgct tggactattt tttggttgta tatcaatgag tattggtata
      421 aatatgtttt taaaaccaca tacaattgct cctggaggac ttagtggtct atcattagta
      481 ctaaacaagg ttacaggact tccagtatca gctatcatgt taattatagg tgtcccatta
      541 gtaatacttg cttttagaat tatgggtaca aaaaattcat taaaaacttt atttggaaca
      601 gttgtatttt cagctatagt tcaattaaca gacccattat caaaactaag atttactaat
      661 gacttattat tgtcttctat tgcaggagga atcctagttg gtataggttt aggaataatg
      721 tttaaatcag atgcttctac tggaggaaca gacttaattg cactcatact tagtaagaaa
      781 ttcccaggaa taaaagctac aaaattcatg tcatgcctag atggaatggt tgttatatct
      841 tctggtatag taaatcgtag tttagaaact gctctttact ctggtatagc actttgtgta
      901 ttaataaaaa tagcagatat gataatggaa ggatttgacc attcaaaagc attttttatt
      961 atctctgatg agcctgaaag tttaagacaa gctataactg aagaacttga tagaggtctt
     1021 actattcttg atggtaaagg tggatacact agagaaaata aagaagttct attagtcgta
     1081 gtttctaaaa aacaagaact ttatctaaag agattagtta aaagaactga ccctactgca
     1141 tttgttattg ttacagatgt acatgaggtt cttggagaag gatttaaaaa tttagagaac
     1201 taataaaaat taatatttta agtatatata ctattttaat taaaatacga tttattcaaa
     1261 aagagtgtct cataaacttt ttagttcatg agacactctt ttttgtataa aatcaaatgc
     1321 attttcagta ttttaacaat aaaaacagga ttatctatat tttgaggcaa ccactttatt
     1381 gaaattttat ttagaaaaca atcattacta aataaccagc atagatatta aatgattata
     1441 tctattgttt tttcaattca tattgataac aaggaacatt tttcacagta tttccagtat
     1501 gaattttttt gatatacttt cctgtacatt taaatcctaa taaatctaat gattttgtag
     1561 aattttggtt ttcttcatag gttattgcaa ttattttatt taagtttagt tctctaaatc
     1621 catactgtat tactcttttt gttatctcag tagcaaaatc atgtccccaa tagcttggat
     1681 ttatacatat acctatttct gcttctaatg ctttaggatt tatattatta aaccccatat
     1741 tcccaataac tttattgtct cttttatata ctatagcaaa gtggccaatt ttcccttttt
     1801 tatatggatt tagaaaaaat gattttataa actttcttgt atcttctaaa gatttatgct
     1861 cactaaatgg taaatgtttt actactattt tatttttata acagtcaaaa aaatcttcaa
     1921 catcatctaa tgatgcaggt cttagtatac aatttctagt ttctaaggtt ttcatttgag
     1981 gatattcaga atcagacatt tctaatcccc ctttatacat taatctaaat atactgttca
     2041 tatttaaaat acgatattaa ttatataaat gttctcaaat taaccttatt tttattttta
     2101 ataaaaacta attactatat gaatctttca aatttacgaa tttatctcta tttttatatt
     2161 aaattacttg tgaaatatgt attctaaatt atatattatt agatatcatg cttaaaaatt
     2221 ctttggttgc taaggataaa gatatatctt ttaaatggca gtaacctata tttctcttag
     2281 gtattggctc ttttatatct aatttaaaca atttctcatt ttccaaataa tctatgctaa
     2341 attcttctat aacacaagac actccaagat ttatatacgc aaattctaaa agtaattcat
     2401 gagaacccaa ttctatatcc gggtttagtt ttataccttt tgataaaaaa tattcattta
     2461 cataaagtct tgaatttgct ttattttcta gcattattaa aggcaatgtg tttaattctt
     2521 ccaatgatat tttcctacct ttgtattcta tgtaatcatt tgcacataca aatatatcat
     2581 gtatttcaat acactcaaca atatttagtg tatcatcttc tattggcatg tttataattg
     2641 ctatatctat attcccatct ttgagtaaag atataagttc tctactcgtt ctatttattg
     2701 tagatacatg tatatgtgga tacttcttat gaaaaatttc taaatatttt aacaagaaaa
     2761 aacgtgcagc tgtatctcct actcctattt tcagagaacc gtattctaat tttttaaatt
     2821 tatttattct atcttctcct gatgatatta actttaatgc agtagtgaca tgttcactta
     2881 gaattttccc ctctggagtt aattttactc ccttattgtt tctataaaat aataaagtat
     2941 ctaattgttc ttctaattgc tttattgact ggcttacagc tggctgtgac ataaacaatt
     3001 ccttagcagc aagagaaaaa ctcttattat ttacaactgc attaaaaacc ttataaagtt
     3061 caagttttat attcatatat aattactcct tatgtcaaat attagtatta tttattttac
     3121 ttataattat atttgaatta taatatacat ggtactaata tgacaatatt aattctttag
     3181 gaggatttta gataatggat agattagttg gaactgtttc aagaggggtt agagcaccta
     3241 ttataagaca aggagatgac ttagttaaaa tagttgttga ttctgtttta aatgcgtcaa
     3301 aaagtgaaaa ctttgaagtt agggacaaag atgtaattgc cgttacagaa gctgttgtag
     3361 ctagagcaca gggaaattat gctcacgttg acaatattgc aaaagatgta aaagataaat
     3421 ttggagatga tactgttggg gttatattcc caattttaag tagaaatcgt tttgctatat
     3481 gtttaaaagg aattgcaaaa ggatgtagaa aagtcgtatt aatgttaagc tacccttctg
     3541 atgaagttgg aaatcactta ataagtattg atgaacttga tgataaggga ataaatcctt
     3601 ggtcagatgt tttaacagaa gaaaaataca gagaactatt tggatataac aagcatacat
     3661 ttactggtgt agattatgtt gattattata agaatttaat caaggattgt ggtgcagagg
     3721 tagaaatagt atttgcaaac aatccaaaaa ctattcttaa ctatacaaca agtattttaa
     3781 cttgtgatat acatacaaga caaagaacaa agagaatttt aagacaaaat ggagctaaaa
     3841 aagtatattc acttgatgat ataatgacag caagtgtaga tggtagtggt tacaatgacc
     3901 agtatggact tttaggttca aacaaagcta cagaagaaac agtaaaatta ttccctataa
     3961 attgtgatga agttgtaaac aaaatccaag gtaatataaa agaaataaca gggaaagatg
     4021 tagaagtaat ggtttatgga gatggagctt ttaaagaccc tgtaggtaaa atatgggaat
     4081 tagctgaccc agtagtatct cctgcttata caaaagggct agagggaact ccaaacgaag
     4141 taaaattaaa atacttagca gataatgatt ttgctgactt atctggtgat gagttaaaag
     4201 aagcaatttc aaaatacata gttgaaaaag ataataaatc tgatgattta acaggaaaca
     4261 tggtttctca aggtactact ccaagaagat taacagacct tataggttct ttagcagatt
     4321 taacatctgg aagtggagat aagggtactc ctattattta catacaagga tatttcgata
     4381 actatacaaa atagtatgtt ttaataagat ttaatttttt tggattatat atattaacat
     4441 gaaaatttat taaaacctct taatagatat gacttttcaa gagttatatc tattaagagg
     4501 tttatttaat gttcacagat aagatatatt taaataattt aaacaagatt gtcagaaagt
     4561 tatataatct taaaaattta tataactcta attcttattt atttctgaaa taatatcact
     4621 cttcaaaatt tgtcttactg gaataattac agcaactata ctaatagtga tatttaaaat
     4681 aatcatacct atgtatagag gtgtatttat tttaagaatt ggatttatat ataaatatac
     4741 acgttttacc ataaaataaa tcataaattg tccaataaca cttccaatta ccattataat
     4801 acttgcatag aatccatata aaaaaccttc tcttatcatc ataagtaaaa acttattatc
     4861 cgtaataccc atagctctta aaattccaaa ctcatgtctt cttgaaaaaa ttaagtagct
     4921 tactgtattg attatatgga acaaacttat tgcaagaagt acaaatacaa taccatatat
     4981 aaataagagt ttttgattta agtaggtatt atttttttca atagcaatgg tataatctgt
     5041 tacgatacat ctttttacat cacttacaac actttttatg ttctcagaca attcctcact
     5101 gttactatct tctgtctttt ttatacttac tgaattataa ttttcgatat caaagttatt
     5161 tttcatttgc ccattcgtca taactatatc cataccataa tcaccaatga aatatatgtt
     5221 atttgccatc acacgtttta cagtagcagc aactacaaat tcttttgttg tataatcatt
     5281 cttattttct tctttaaatt taacaatttc atctgttggt ttcattgtct ttggcacttt
     5341 aacttttatt gtatctcctg gatttatatc aactgcatca tacatcccag ttccatccat
     5401 aggtagtcta actataacct tattattttt aaccatatca tgggtattaa tctccccatc
     5461 tataatataa gaatttaatc cttctaacat accattgtta taaccataaa tatttgtttt
     5521 taaaagatag ccaccttcat tttgctttgt acaaatacca tcaaaaaaag tctttatcct
     5581 gtaatctttt tcaagaggtt taaagaaatt tttccaaaat agttgttctt ctttaatttg
     5641 catagctcca aataaatatc ttactggata gacttttgat attccctcaa cattgtttaa
     5701 tcttgaaatt ttatcttttg gtatacctac atcaaaatct gttgtttgca tagttatttg
     5761 gtagtcagaa tttaaaccat catcagcttt cattgtaagt tcattattat ttttagtaag
     5821 ctgtatagag taactagaac atagaaatat aattccacca agtgataatg aaaacaaaat
     5881 tccaataaac attccctttt tttgagtcat gtatttatga gataatactt ttgtcatgtt
     5941 agagtgtttt acactttcta atattctctt tttcttatta gtaatcttaa agtttttcat
     6001 agattctata ctagagtatt tattcaactg atgtacaaca cgtacagcaa ttaaaattaa
     6061 caacaataag ataaataaaa agcctaaata aatagatttt tcacttataa aaaatgctcc
     6121 tggaacaata tcactactca aaaatatatg tggaaattgt tcatatattg tagacgctac
     6181 tccaatacct aagaagcaac ctataggaaa tccaacaata aaaagtaaaa ataactctaa
     6241 aaatagtaga aataaaagtt gtttattatt agcgcctaat acttctaaaa ccccatattg
     6301 tgatattctc tgaagtattg aaacatggaa aatactatat actgctgctg caccaaacac
     6361 tccaacaagc aatataattg catttgtatt tagttctaaa ttttttaaga actcaaatat
     6421 attatatttt tctatatttt ttggtggttt tactccaaat tcaactgaaa gagaccagtt
     6481 tatataagtt ttttcttttg atatgttgaa ttttttcata aatttataat tttgcttttt
     6541 aatattttta ttttcatcat attttacata aactatataa gaatcctttt ctttaggctg
     6601 aaaataatcg tttacaaatc cctccagagc agtttctggg tttgaaagac ttgataaaat
     6661 accacataac ttatagattt taccatctaa attgatttct gttccaattt ctttgtttac
     6721 atttaaattg tttagagaat atgtgtcaag tactatctct ccatctttac taggaagagt
     6781 tccttttaat aattttctac ctgtcatgtc taaatatgaa gaatcagcat ttaaaaattc
     6841 tataataaaa ggttcatcta tctgattttt aggttttgta acgccaagtc tatctacagt
     6901 gtattccttt gattttttat tttctttaat tttattaagt tgttccttat ctactttata
     6961 gaaataatga taatctccac tatcttccct tatcttttca attctacttt tgtctgcact
     7021 atgaactaaa gaaccaattc ccgtcaataa tgctactgat agtactatgc ttaaaactat
     7081 agatatagat tgttttttat aatgctttat atattgaatt gaaaatttta ctagagacat
     7141 catagtaatt caccaccagt attaaccaca actccatctt caatatggat aattgagtcg
     7201 catacttgtg ctatattttc attgtgtgtt accataagta tcgtttgatg gaattttgca
     7261 ctactttctt ttaataaaca taccacttcc attgtagttt tactatcgag atttcctgtt
     7321 ggttcatctg ctaatataag cgcaggttta tttgccaaag ctctagcaat tgctaccctc
     7381 tgttgttgac caccagatag ttcgcttgga aattttaaac gcttatccca aattcccaat
     7441 gtcttcatca gcatttcaat atattcatgg tctatatggt ttcctttatc taatgtaaca
     7501 ggaagagcta tattatcata agtgtttaat acgggcatta aactgtagtt ttgaaatata
     7561 aatcctatat ttcttcttct aaacactgtc aaatcttttt ttcctatttt agatatgttc
     7621 tttcctttaa ttattacatc acctgaggtt ggattatcta atccacctat aatatttaac
     7681 aatgtgcttt ttccagaacc agaagttcca actatagcag taaatgtatc tcgttcaatt
     7741 tctatactta ctccatttaa ggcttttact ttagtctcac cttttccata gtgttttact
     7801 aaattattcg tcactaatat actcatttaa tttctccttt caatacagat atatgttcta
     7861 taaaatattg taagtgacga taattacact catcctacaa aattagttta aactcttaca
     7921 attctgtaag aagatactaa aacaacatcc acttcctagt ttagattcta ctataatgtt
     7981 tccattttct ttttctaaaa ttaatcttgt aagatataga ccaatccctg tgccattttg
     8041 gttttcaaca tttttacttc tgtaaaatct tttaaaaata tcatttagtt ctctactatc
     8101 aatacctatt ccctcatctt taatagtaat cttcgtatat agttccattt ttattacaga
     8161 aatagtaatc gtgctatctg atggtgagta ttttattgca ttttctaaaa catttacaat
     8221 tgcttctatg gtccactttt tattatgaac taattttatg tctgaaaatg gttcgagatt
     8281 tatccttata tttttagctt ctgctttatt aaagatagta ctgatacttt gaataagagt
     8341 atctttaatt agtagttctt ctacttcaaa ttctataact ccatcctcta atttagtcat
     8401 tttaaataag gattgtaaca gccagtcaat cttaaaagtt tcatttttca tcttttgtaa
     8461 aaactccttc ttctgtaatg tggaaatatt tatattctcc agaagttcac aataaatggt
     8521 tatatttgaa agtggagttt ttaattgatg tgacatattt gatattaaac ctttaatcgc
     8581 ttctttttct gactttgact gttctacctc tatttctatc atatccttaa ttttttttac
     8641 ttggtgagaa atttttgacg ctcttgtatc ctttgtatct ggataagtaa cttctttacc
     8701 ttccaatatt tgatttaaca tcaaatttaa ttcatcatat ctttttcgat ttattttagt
     8761 agatactata aatataacaa ctgtacatat tataaaggct aatataaaca tattattcta
     8821 cctcattcca taaataaccc attccataag ctgtttttat atattttgga ttagatgggt
     8881 catcctctac ttttactcta agtcttctta tatttacaga tacaatatta tcatcaacat
     8941 aattttcttc gctgtcccaa atatggtgta aaatttgttc ctttaataat atttgacctt
     9001 tattttcaat tagataactt agaagcttat attctacaga gctaagttcc aaacattctt
     9061 tatttttata tacttttagt aacttttggt ccaattttat tccattggaa tatattactt
     9121 tattattcga tttttttctt attgctactt tgactcttgc ctttaataca gataaagaaa
     9181 atggttttgt aatataatca tcaagcccta tttctaatcc ttttacttca tcaatttctg
     9241 agtctcttgc agtaagcatt ataattggta tatctgactt ttcccttatt atttgacata
     9301 catcaaatcc atctccatct ggaagattgc agtctaagat tataaaatct atatttttac
     9361 tattaaatat atttaatcct tcttgttttg tataagcctt aaatacatta aatccatcat
     9421 tctcaaatgc ataaaaaaga ccttcattta agtttatatc atcttcaata attaataagt
     9481 tcaattttac tctcctttag attttttaga taaataatta ttttcttgca ttatcatact
     9541 aaaaatattt taattttatt tatttcacta aaaagattgt atttaaattt gttttcaaaa
     9601 taaaaacatt ataatcaagc atatagttat atatttccca atttaattac gcttaaattg
     9661 aaaatataac tttattctta tataattaaa ttatacaaca ataaagttat attttttaaa
     9721 tatattttta ctagggggaa tagaattgaa aagggttgat gagagaaata ctatgtttgc
     9781 aagagcaaat tacaaaaaag atagtactgc ttataatgac tattataaga aaaatcctga
     9841 caaaaaagaa attgatgata gtataagaaa tagaccaaat ttatgtagtg aaggaacaat
     9901 gacttacaat gagttaaact ctccaatggc aagtagtgca ttcgattttt tatctgatat
     9961 caaatcttta tgcgaaggaa aagtttctga tactaaagta gatgtagatg caaagtcaat
    10021 gacaaaaaaa attaagggtc ttgcaaagca gtatggagct tctgtagttg gtataactaa
    10081 attaaaagac tatcatattt atacaaatag gggtagacat gaagaaaatt acggtgaaga
    10141 aattaatcta actcataagt atgcaattgt atttggatgt gagatggata aagaaatgat
    10201 aaatagagct ccaatgatat gtgaagttat agaaacatca aagtgctatg tggatgcatc
    10261 tatcgtcggc atgattttaa gttactatat aagaaattta ggatatgatg ctagaaatca
    10321 tatggatgct aattatttag taatgcctgt ttttatagct cgtgatgctg gtttaggaga
    10381 tataggaaga aatgctatac ttacaaataa agattatggc tctagactta gattaggtgt
    10441 tgttactaca gatattcctc ttttagaaga tgaatatgtt gattttggac tagaagattt
    10501 ttgtaaggtc tgtaaaaaat gctcttttaa ctgcccttct cattcgcttt ctaatgatat
    10561 taaaattggt gatgatggaa aatataattg ggtaattgaa catgagacat gctatattaa
    10621 atggagatat ttaggtacag attgtggtat gtgtatatct gcttgcccat ttagccaaaa
    10681 tctcgaaact ataaagaata ctacttcatt taagggtaat aatgagctta ttcaaaaagc
    10741 tttagatgag tatacttcaa aatttggtaa aagaatattt atacctggaa atccatcttg
    10801 gttgaaataa ttttatttaa taaagaatct gtactagaat ttatcatagg acaggttctt
    10861 tattaaatat ataaattttt aaatactttt tctcgtttat aacaattcag caatgttttt
    10921 agtctataat tgacattata aaatattaaa ctaaaaggag taactgtatg gaaaaaatat
    10981 tagtagtaga agatgattct atattaaata aaactctatc atataaccta attgaagatg
    11041 gatatataat tacttcaaaa tttacagcta aatctgcact aaagtctatt tttgaatgtg
    11101 aatttgattt aataattttg gatattaatt taccagataa aagtgggttt gaattatgta
    11161 atgaaataaa ggaaaattac aatataccaa taattttttt aactgctaat gatatggaat
    11221 gtgatatgat taaaggctat gaacttggag ctttggatta tataacaaaa ccatttaata
    11281 tcaatatatt taaacaaaaa attaaagctt ttttaaatca tcttacaata aaaacaaaac
    11341 aagattacta taaggatgga tatcttgaaa ttaacttttc tgagttatct gccaatataa
    11401 atggaaatca aattatattt acaccattag aatatcgtac tttaaaactg cttactgaaa
    11461 atcctaaaag tattttaaca aggaaagtac ttttagaaaa actctgggat atagatgcta
    11521 actttgtaga tgaacatact ttaacatctg ttataagtag gattagaagc aaaattgaaa
    11581 aagacaatct taagtatatc aaaacggtat atggtatggg atatatgtgg ttaggtgaaa
    11641 gaaatgaatt ttaaaaaatt ttcttttagt tctatttatt taataattgc tgttggtata
    11701 atttttacag ctattttatt tagtatctca atttatctaa taactggtga tttaaaacta
    11761 attgctctat tattaatata tacaatggta ctttgtggat ttatagcatt aataatattt
    11821 ttacttcata aaaaaatagt tatattttgt tctaaaatat gtcacacttt agatagtatg
    11881 atgaatagtg aagataatat tgaaattgaa ttagaagaag aaactatttt atcacgtatc
    11941 aatcacagat taattagaat gtatgaagtt attcaagaaa atcgcaatag tattgctata
    12001 gagaaagctg atttacaaga actagtttct gatatatctc atcaaattaa aactcctatt
    12061 gcaaatttaa aaatgattaa tactactcta ctaaatcaaa catttaaaac agaaattcaa
    12121 aaggattttt taatggatat ggaaaaccaa ttagataaat tagatttttt aatgcaatct
    12181 atggtaaaaa cctccagact agagacaggt ataatcacac tatctaaaaa gaaaaattca
    12241 atttatgaaa caattgctac agcacttagt ggaattttgt ttgatgctga aaaaaagaat
    12301 attgaagtta cagttgattg tgacccaaat ttatatataa ttcatgacaa gaaatggact
    12361 tctgaagcta tttttaatat attagataat gctgtaaaat acacaagttc taatggtaag
    12421 atacgtgtag ctacagaatg ttgggttatg tatacaaaaa tagatattat tgataatgga
    12481 aaaggaatat cagaaagtcg ccaagcagaa atctttaaaa gattttatcg tgaagaagat
    12541 gtccatgaca tagaaggtat tggaataggt ctctatcttt caagaaaaat tatatctctt
    12601 caaggtggct atattaaagt tacatcagat attggaaaag ggtcgacttt ttctattttc
    12661 ttacctaata aataaatttt taaaaatttc atttgtaatg attctgcaac attttggttt
    12721 tatactgtat ttacaagatg ttaaggaggt attattatga gtattttaca agtaattaat
    12781 ttaaagaaat attatggaca aagttcaaac attacaaaag ctcttgatgg tgtaactcta
    12841 tctattgaaa aaggcgaatt tatttctatt gtaggtacat ctggtagtgg caaatccaca
    12901 ttattaaata tgatgggagg attagataat cctacatctg gaaaggttat tataaagggt
    12961 aaggaattat ctactatgtc tgatgaacag cttacaatct ttagacgcag aaatataggt
    13021 tttatatttc aaaattataa tcttgttcct ttacttaatg tatatgaaaa tattatctta
    13081 ccaataggat tggatggaga gaccatagat aaggatttta taaatgaaat tataaatatg
    13141 ctttctcttg aagaaaaatt atatgatata ccaagtaatc tttctggtgg tcaacagcaa
    13201 cgtgttgcta tagctagagc acttgtaaca aaaccagcta ttatactagc tgatgaacca
    13261 acaggtaacc ttgatagtag aactagttca gatgtactga gtttacttaa agtgacaagt
    13321 aaaaaattca accaaacaat tgtaatgatt acacacaata atgaaattgc acaactaact
    13381 gatagaatta ttcgtattga agatggaaaa attgttaact aggaggtgta gtatatgttt
    13441 agaaataata atcgcacatt tataagaaaa atagctttaa atgatttaaa aattaataaa
    13501 cttaaaacat atctttcagg tatcattata atgatttcta catgtttatt attaacagtg
    13561 accttagttt catataatgc ctctgtagat ttagttaatg catctccata tcatgctata
    13621 tataaatctg tagatgaaaa agcaaaaaat atactatata aaaataaaaa ctttagtggc
    13681 gtaggaactt acaaattaat tggaagtaat aaaaagacag attgtattat gtcgattgtt
    13741 tatgcagatg atacagcaat taaacttatg aattttcaac cattgaaagg caaactacct
    13801 acaaataaaa atgaaattgc tatttcagaa aaatatttac aggaatttgg tttagataaa
    13861 gatattggag atagcattaa attaaattat tatgatgata ttacgaataa agaagttcaa
    13921 tgtgatttta ttattgttgg atttctagaa aattattatc aagataatgc caagcaatac
    13981 tatacagtcg tttcaaatga ttattttaag aatatagctt ctacaccttt acaaaataaa
    14041 agtaatactt ttgacgagtc aagacctgat actgtagatg tattagttaa actatcagaa
    14101 gaaaatacag agaaagattc agcttcaatt aagacacagt taaataaaat tggtttatct
    14161 ttaggtatta agaaatataa tatatactta aatgataact atattgaatc aaatttaatt
    14221 gatggtgagc agattattac agttttagta gttggaatag ttgttctttt ttctagcgtt
    14281 tttgttatat atagtatttt ttatatttca gttgttaatt cagttcagat gtatgctaag
    14341 ttgaaatcgt taggtatgac ttcttttcag ttaaaaaaaa ttatttctct acaaggaaat
    14401 attttgtcaa ttatttttat tccattaggg gttatagctt cttgtataat tgcttacata
    14461 attcaaccat tagcatggca aatgatagct gatttattta taattttaat tttatcactg
    14521 gtaatgtttt taactgttag aatttcttta tttaaaccag ctagaattat ttctaaaata
    14581 tctgctattg aagccatgca atatacagaa actaaattta gaaaaaaagc aaaaaatttt
    14641 agttatataa atataaaaaa tctagcatta aagaatatcg agtcaaatag aaagaaaaat
    14701 ttgattgcat taatatcgct aagcattagt ggagttttat ttatttcaat cgctaatctt
    14761 gctaattcaa tagatttcaa aaaacaacta tctcaacaat ttgtctataa cgaagattat
    14821 ataattagca ttaagagtga taacttatat gagcatatta cagaaatcca acaaaataat
    14881 ccactaacag attctcttaa gaatgaaatt aaatctattc atggagtaaa aaaattaatt
    14941 gaatccaaat caattaaaag taatattata gaaccttaca tcaaagatag agacgaaaaa
    15001 caatttatta ctctaattaa aggtattacg cctgaacttt caaaatcact tgaagaatat
    15061 attgtcagtg gaaaaataga ctatacacat ttagattcag atagtttaat tataaataaa
    15121 tatagaacaa aatattatgg attaaattta aaagttggag atacagttac atttaatatc
    15181 tttagtggaa atgatattat taaaaagaaa atgaaaatta taggaatcat tgacaattcc
    15241 aatacaggag gtatgttttt tgcttcagac aaaactttag aatctctaac accatataat
    15301 acaaatttag atttttctat tttaatagat aaaaagcatt ctaaagaagt tgaagaaaag
    15361 ttgttaagta taattcagaa aaattcaaat ttaatgcttt attcatatga agatgattat
    15421 agaatgatta ctagagcatt tcaatatata attatagctt catacatttt tgttggttta
    15481 atttcttgct ttggtatact aaatatgacc aataccctaa taaacagcgt tttaattaga
    15541 aaaaaagagt ttgcattact tcaagccgtt ggaatgacaa gaaagcaact gcgaaatatg
    15601 ctttatagag aaggtctaaa cataagtatc aaagctatat gtacttcaag tacactaggt
    15661 tattttggtt caaatctact ttgcactttt ataaaagatg taattagatt agactttatt
    15721 aattttaaat tttctatatt tactatttta attttttcat tcgtattaat tggtatacaa
    15781 gttttagtga ctgaattact tgtaagaaat atagaaaaaa aatcacttac agaacgctta
    15841 cgttctcagt aagaatgtat ataaaaaata gccatttttt atacaagttt taatatgatt
    15901 ttttaaaagc tatagggata gaaaattttg actttacata attttctatc cctatacttg
    15961 tttttatttt atacagatac acttacttat atctccgagc aacatcacca gagacataaa
    16021 caagcatatt ccttattttc taaatatgtc aattgcatga cttgtaaccc ctactaaatc
    16081 ttcacgttca caagtagcaa ggtgatattt taaatataat gcaaatgcat catcatccat
    16141 agagtctact gcttcacgca tatataaagc caaaccatct gatgcgacat aatgcagtct
    16201 agttacatta aatgcagaca tcaaatcatc aatgttttct ttacgtacaa gctcaaacaa
    16261 atcctttggt tcagacttag cagcaaatgt ctgtggatca atcaaacctt tttcaatata
    16321 ttcagataca ttaatatttc ctctatggaa cccctcgtca atgagacagc catcagatat
    16381 aacatatgca gcaaaaacca caccaccagg ttttgttaca cgaattgcct catgtaaagc
    16441 ttgttgttta tcttctttgt tataaagatg atatagtggt cctaacagta acgtaatatc
    16501 atatttatta tctgggaaaa cagataaatc catagcatta ccctgagtaa tgcttatatt
    16561 ttcatttgat tgagtatttt tatggaaaac ctctatatta tgttcgacta attccactgc
    16621 gtcaacatca tatccctgac gtgccagtgt gtgagaataa cgaccagttg cagcgccaat
    16681 ttcaagcaca caatcacctg attttatgta cttatcaatg taatgcatag tagtgagaaa
    16741 ttccaccatt ccatgtttta atgcaagtcg actatcttca tcataagtat tataaaagtc
    16801 aattaagtat tgttttgttt ccataatttc acctcttcta tattagttaa taaacatcaa
    16861 atagacaaat tccaatctgg tttttcttgt cttataaaag ctgttaatat atttttcaac
    16921 attttttcag cactatatct atctaatgtt aatttttttg ttgctgttaa gacagctatg
    16981 ccatgagtat aaagaaataa atctaaaaat attacttttg cacattccaa ctctattcca
    17041 atgctttccg aaaaaagtct tgcctttttt tcattgtcaa tttctttata aaaatcattt
    17101 gcctcttcca tcatcaaatc taaatcattt ataaataaca acttaaataa atgagtttct
    17161 tcttgagcaa attcaatgta tgaaagcgga agcagtaaat aaggacttac acttttagaa
    17221 ttactataat taacaacata ctgattatag tattcatatg caaaagcaag aaattcattt
    17281 tttaattcat tcatgttttc gtaacaagta aaaattggtc gagtggaaca ctgtaattta
    17341 cttgcaatac tcctcgcatt tacagcttca aatcccactt ctcttgtaat atccaagact
    17401 gtattcaaaa tcatttcttt tgttatcttt actttaggtg gcatatatgt tcacctctcc
    17461 attaaatttt tataaaacac atatgttata taactatagt aacatatcaa gaaattatgt
    17521 caagaaaaag ctttgcattt ttttgcaatt cctaaaactt ataaataaaa catgagttgc
    17581 aattaatcta ttaatagata acagcaactc agattttcct ttaaatactc ttctttttgt
    17641 ctaatatttc atatacacaa tcttctattg aattaatatc tttttctttt ctttttttag
    17701 aatcaattaa aatgaaatac agtataaaac ctacagcaag tccccatgtt ccgcctttag
    17761 cagcaattac acctcccata agtccaatca atcccttctc aacacctgta ttacatagct
    17821 ccattgatag ctttgtacat aaatatcctt gaactaaaag tgttactgac aatgctaatg
    17881 gtataagagg tgtagcaatc tgcgcaattg gataaaaaca gataaaaatt gctgaaaccc
    17941 atactaatgt acccatgcca ctaaaaacag actgcatggc ttcctttcca accttgtacc
    18001 tttgagcaac acttcctgta agtgtcgcag ctaatggacc gcacattggt atatatggag
    18061 aaaagattgc cataaaaata tttcttatcc cacttataac attagaccta tttgaattga
    18121 aatctatata ttcatctttt ctattttcac tttcagaaag tactaagttt tcacctgtta
    18181 taaaatcacc aaaggcaatt atgtatatca taaaagccat tggtatccct tgtataaata
    18241 acattacact tggaaaacct attccaaaag gagatactgt atttatcaga tttttaaaat
    18301 ctactatgta aactaaattg tcaaaactaa atctaggaat ttctatttct ttactaaata
    18361 tacctactat taaactcact aaaatagctg atactacacc atattctcct aaatgaaata
    18421 aaaatttatt cttaactttt agagtatcaa atctttcaga aaacattaca aaacaagcaa
    18481 ccaaaattcc tactgttata gatataggat aagaatcaaa tctcccttta ggattaaact
    18541 ctgatattat agtcgatata ccgacaccca ttagtattcc acctttaata gaatttggta
    18601 tcttactaac taactttcca gctacaccag ttatacccat taaaataaat attattccta
    18661 aatctatttg taaagctgtt aatgcttgta ttctttcaat gcccatgctg aactttaaca
    18721 aatatgcagt tgtaagagtt atagaagctg taatccagcc aggtacaact gggtctccca
    18781 taaaaacatg caaacagtat aatattgagt taatgatagc catactccat gccacttcat
    18841 agggtaatcc caaaatttgt gtactaaggc caattgtgcc taaacttgtc atacttgata
    18901 ttataccttg aatagcttct ggtttctcaa atctgtaatg tataaatgga attcttatct
    18961 taaacattcc aaattttata tgaggttgtt cccttctagc gagtctttcc ataacttcac
    19021 tccacctttc aataactctt ataagtttac aactttataa ttgtttataa attatcaatg
    19081 tcattaaaat tagtatataa catgcaaatt atataaacaa taaattaaat ctataaaatt
    19141 gatagatttt gtgcatatat agaaagaccg cttcattttt agttacttaa atcacttaat
    19201 attagttatt taaatcactt gataaaggtt ttttataaaa ttcaatagtt ctattccatg
    19261 attcaaactg tccttttgaa tttccttcta cagttccacc tgaagaaaaa atccctctac
    19321 tcatactcat acataaagtc tcctttagag gcataatata tggaattggt aacggataac
    19381 ccatattatt gtatgttaat aattctacgt tatatggata attattttct tcaaagattt
    19441 ctaatgcctc taaacaagct tcataactat tccatatgtt atcttctttt ccagcaatca
    19501 taagtatatc tgctttggaa ttttctattt ttattctagc ctcttttcta ttctctgctc
    19561 ttttaagact tttcttataa gtactattaa atccaaatgg aatatctttt gatatatttt
    19621 ttttctgttc ttcaaagaat atatcattgt ctactttgat atatggaaat ggctctcctt
    19681 tatatgacca tgatgaagta tcatttccac tcatcaatcc attaagagct tggaaacaat
    19741 aaatgtgagg ttgtgatact acaacctttt taatttgttc atatcttgaa gcaagtaaaa
    19801 aggccaattc tccacccttt gatgtcccat gtacaaatat ttctttagta ctggtaattt
    19861 cattttcact aatccactca aatacttttt caaaatattc taatggaacc tcttctaatt
    19921 tatctggtaa cccttctaaa gcaaagtatg caactgttag tacattgaat cctctagatg
    19981 caagtggagc tgctaaaagg tctagagcgt ctaaatttcc atcagaacca cctagcatta
    20041 aaattgtttt attattagaa ttttgtttat aaaataattt tcctataaac tcatcagata
    20101 tgtattttgt ggtaatatct tctgatttaa atattctctt taattcaact tcttttcttt
    20161 caatagaagt ttcaaatatc atattcataa ttattggttt atcaatagat atattttctg
    20221 caaaattttt accttcagtt ttagattttt ccagcgaata aattaacccc atacaattat
    20281 cagccttata agtaccttct ataggttcaa ctaaatctaa atctacttct cctttttcat
    20341 ttgaacaaaa cactccataa gatgaaaatt cttctccctt acaccatgga aattccattt
    20401 tcacacttat tttaagttta gtatttggaa ttaagtctga aaccataatc ttaagtcttt
    20461 catccacaaa tgattctaca ttgtatacat ttactttcat aatctatttc tccttataat
    20521 aattatttat gttttatata aaacagcttt atctaataca agataaataa atttttaaat
    20581 taagacacca tattgactat ttcattttat caacatattt catctttgtc aacatattgt
    20641 cttttttagt aatttaaaat tatggtctat atgaaatcca gttgattttt ggctaattaa
    20701 agataggaat gctattaggt ttagaatata tatattcaaa ataaaaaacc actcatttaa
    20761 agaatggttt ttaatataaa ctatttgtta ttaataagga tattttttta tttaaattta
    20821 tataatcgaa catctaatat ttaatgttta ataaaattat gcatttgcaa aagtatatat
    20881 ggcattaact cttgctacat ataaattctc atcactacat ccaatatatc tagcatattt
    20941 ttcaatcttt tcttttgcat tttcaacatc attttcatcg ctctccatta actcatttat
    21001 ataaatatcc attaatgacg ctttatattc tcttatatca tagcctaaaa attcagtcaa
    21061 tctctcaatt tccttactaa aatctccatc ttcttttacc aaaaattcgt atacatcttc
    21121 cctatatgga tttaaagtta ttatttgttt tactactttg cattcgtcag ccttcccaat
    21181 aaaaccatct ttataattat taaataaggc attagatttt tttatagatt cttcatcaat
    21241 ataagaatgt accgcagtta tacgattttc tataagggca tctacaacag cataatgaat
    21301 tttaaaacaa tcattgtata aataattgct cattttcttt attgtcgatt ctatttctaa
    21361 gaagctcgcg tggccatttt ttttattttt atttggtata ataaaagttt tattcaaatt
    21421 attaaaaagt ctcttaaaat ctaaatattt ttcacaataa acacttttaa aggtatcgat
    21481 atctatagtt ataattccaa aacttactat agtctcaatt cctttcttaa aagactcttc
    21541 tatatatttt tctcctaaac ttaaacctct atcagatatt tgctttagat tttgaaaact
    21601 atttaaacaa tctctttcaa agtttttaga tatttctaaa gcatataatt taaagatttt
    21661 ccttatctta ttataattat tttttgtatc atcaaatctg ataatagctc catttacatc
    21721 aaaagtaatc attgagtttt aacctcccca ttagtttcat caataaaata aatttaatat
    21781 aaactttata atcataatat taaacttatt tatactataa ttattaattt gatgataaaa
    21841 gctattttcc ttctaaataa aaaatttgtc taaagtttct aaaaaattta gacaaatctt
    21901 aggttattac tctttaaatt atttttaaat tattccaaat acgccaaata atattggtat
    21961 aaatatagct ggtaacaaat tggctacttt tatattcgtt aatttaagta catttagacc
    22021 aagtcctata attaataaac ttccagctgc tgtcatttct gtgactacag gatcacttaa
    22081 aaatccattt aaaaatgatg ctcccacaca tataatacct tcatacaaaa atacagatat
    22141 tgcagaaaac attacaccta tacctaaaga agcagtaaat ataattgaag ctattccatc
    22201 tataacagat tttacaaata aagtatcatg acttcctgta agaccacttt ctaatgaacc
    22261 aactactgcc atggctccta tacagaataa taaactagat gatataaaac cctctgctat
    22321 agaatctttt ttatttcctt tagaaaattt actttgtaaa aaagcaccca acttatttac
    22381 ccatttgtca atatctatta attctcctat cagagcacct acagctacgg atattattgt
    22441 cactaatgtg ttttttcctt ctagtgctcc tgatatacca atgtacaata cacataaagc
    22501 aattccattc attatagtat cgcttactct ttgaggtaat cctcctttta ttataagacc
    22561 tactatacat ccacctgcaa ttgctagact atttgctatt actccaaaca ttttttctcc
    22621 cctcgattag ctaattgaaa tttatcctat tattaaaacc taaacatcta tactttgtat
    22681 tggatatttt aaatattcca aaaattcttc aaaacctttt ctagatatat ttacagtttt
    22741 agtatttatg ttaggatgaa aatttaagta atcttcttta attacatctt tatctatgta
    22801 aagctcaact tttctttctg tatcatttat taatgaaaaa ggatttacac ttccaggaag
    22861 aagtttaagt acattgtata gtctttcagg tgaagcaaac gataatctag aacttcctat
    22921 cttatcttta agtgagttta aatcaacttg tttttctcct ttaactacaa taagataata
    22981 cttatttcct ttggcatttc ttaaaaataa atttttacat tgacacccct ttgttattcc
    23041 atctaaaatg actaattgct ctgctgtata tacagcttca tgctctacta catcatattc
    23101 aacatttaat ttatccaaaa tatcatatat tttagtttca ttcatgctag attcattttc
    23161 atcttgttct tttttattat ttaaatcact catacttttc tccttaaaca cttcatcata
    23221 atatcattgt gaggtattat tctactatag ctattgctct tactggagct ccatcagcat
    23281 cattatactt aaatggtgct gctataaata gaaatttttc tggaacattt tctaaatttg
    23341 taagattttc tatgattatt tttccttttt caaataaaat atgatgcact tcaaatactg
    23401 atgtgtcata tctatccact gatagcatat ctattcctat gccttttata ttagtattag
    23461 ctatatagtt tgcagcttct tttgttaatg taggataacc tacatagtac tgctttttat
    23521 cccaaaattt tgaccaacct gatttaaata ttataaaatc actatttttt atttcatctt
    23581 catatttttt tagatattct aattctatat tctcatttcc cttttcaagt tccaatacat
    23641 aagcttttcc aacaaaattt tctatatcca acttatctag ggtctcacct ttagtataca
    23701 tatgtcttgg tgaatccata tgagttccat tgtgagaaaa tacactaatt aatgtttctt
    23761 gataaccatt ttcttcaata atagctactt tcttgatatc tggtctatta ggctctgcat
    23821 atacaggcat gtcattatgt gtcacatgag ttaaatcaaa aaccttcatc tttatatacc
    23881 ccctatgttt ttattttcta ttatatacct aaattcattt tatttctatc agattttatt
    23941 ccattatata ccatactact atatattttt tataaacctc aagggattta ccgaaaaatc
    24001 ttggaaagaa ttatcagtaa atataacatc ttcacccaaa aaacgtttat accttccttc
    24061 ttctttcttt aaagtaattc tctgtttttg tgaatgatta ttaaaaacca ttatcttaag
    24121 aggaggtttt tttctattag tctgcactct ttttaacatg tattttatgt gcatatcagc
    24181 ttcaggaaat gaatatccac aaaatattaa aaggtcagta tctcttaaag ttttttctgt
    24241 ttcattccaa acattactta aaaatatgtt tgacatattc ttaaaatatg ttggtggcac
    24301 tataataggt tctgttaact caccacactc taaacatttt gtctctgaac tattttcaat
    24361 aagcttcatg acaccacctt catgtggtgt aagagttaca ctattacaaa tggggcaata
    24421 aagccaattc aatgacccat gtatcttata taatttgatt aatggttctt ttggttttct
    24481 ccaatttaac tcctctttaa aatttgtaaa ctccacacca taatcaagca taattggcaa
    24541 atcattctta tctcttaatc cagtaactgt attgtctata tgtatatcat aatttgcact
    24601 aataaaagta gtatcaagaa gcaaatcatt ttccaaaaga ttttcaacta aaagtttatg
    24661 atatttatta tctgttctag gtgtattatg aattgcttca gccattagca gtattaaata
    24721 ttgtcttaaa aaacgtatac tatcacttct gttatttaga ttttctagtc caaaatttct
    24781 aaatgcttct tttctttgtt ctgctaagtc taaaagacct aaaacttctt caaaggtagg
    24841 aaaatttgca ttatctatat tatcttttac tatatcaata ttgaacatct gtttaaagaa
    24901 aatatacaat tctctattca ttttggtatt ataatttgtg ggatttagtt ttttaaaata
    24961 ttcgctaaaa agttcatttt gaataggtag attctctgct gctgaagctc ctgctcctaa
    25021 aaatattgct attttcatat agttcctcct aatataaata ttactcctat ttttatatcc
    25081 attaaatatc catatcattt attttatgat acaacaataa agctgtcttt tactagaaaa
    25141 aatcctatta caagacagcc ttatattata ttaaatcttt aataattcgt aaatagaaag
    25201 agcatatatt tgagtagctt ttataatatc ctctactatt aagtattcat tagcttggtg
    25261 ttctgtttct ggttttcctg gaaaaatagc tccaaatgca acacaattat ctaaagctct
    25321 tgcgtatgtt gctcctccag atgaaagtgg tgttccatca agaccagttt cttcttcata
    25381 tacttttcta agtgtcttaa caagaagagt atcttctgga acatagattg aatccaagaa
    25441 atcatattct tcataattta aattgtattt atctgtcatt ttctttaact cttttacaaa
    25501 atcatccttt ttgtatgtta ctggaatcct tacatctatt cctgcaaatt ctttttcgtt
    25561 atcaatagtt actctaccta tatttactgt tagtttacct gatacatcat ccttgcaatt
    25621 aggaattata ttgtttccat tagcatcttc accaataact tctgctaaaa acttaattat
    25681 attagaatct atacctatat tattaagagc tatacaaagt ctagccactg catttatacc
    25741 agtatcactt gctgctgaat ggacactttt tccaattata cagattttat taccttcaac
    25801 agtatactca aaatttaatt tatcaagttc tttttttaat ttatcagagt attttccaat
    25861 atagattgct ttacctggaa ctgcatttaa agcctttcca actgacaact ctatatcact
    25921 tttgctatca caagtcaaat gaacttgtaa aagacctttc tctgcatttg ttattgggaa
    25981 tctagaatct ggagtaaatc catagtttgg tatttcttca ttattttctt tatatttatt
    26041 tatacatctc caaagatttt cttcatcagc cccaaaaatg aatcttatcc tcttattaaa
    26101 gtctacattt aaatccataa gagctttcac tgcataaatt gctgatattg taggtccttt
    26161 atcatcttgt gttcctcttc catacaattt accatcttct aaaacagctt caaatggagg
    26221 gtaattccag ctttctaaat caccttctgg aaccacatca acgtgaccaa gtatacctat
    26281 cattttttca ccttgtccta tttctgcata tccataatat ccatctttgt atactgtctt
    26341 aaatcctaaa gatttacata agtctaatat acctcttaaa gctttatcta cattttcacc
    26401 aaatgggcaa ttttcagttg cttcagatat aacactaggt atttttacac tttcttgtat
    26461 tgaagaaatc atttcatctt gtagagaatt tactttttct ttaatttgct ctttcatatt
    26521 atcacccttc aattttcatc ataatatact aataaatatt ttgacctttt aaaaaaaaaa
    26581 tatgcttatt ttttcagttt ttttataaat tcaatcgctt ttaaagtccc catttttgaa
    26641 tggtcaaatg taagtccacc ttgaaaataa acattataag gaggtcttat tggagcatct
    26701 gcacttaatt ctatagaaga accttgtata aatgctcctg ctgccattat gacttcactt
    26761 tcgtatccag gcatgtccca aggaacaggt tttacataag aatcgactgg tgcagcttct
    26821 tgtatacctt cacaaaaact tattacttca tcagcattat taagtctaat acattgaata
    26881 atatcacttc ttaagtcatc atattttggt aatacatcat atcctaattt ttcaaaagct
    26941 cttgagcaaa agatagctcc cattacagcc tgagatacta tataaggcgc caagaaaaaa
    27001 ccctgaagta catttctagt tgttccaaaa gtaagaccac attcttttcc tattccagga
    27061 gaagtcattc tataagatat aagctcaatc aaatcttttc taccagctat atatccacct
    27121 gtcaatgcaa gcccaccacc aggatttttt attaaagagc cagccataac atctgctcca
    27181 acatcagtag gctctttggt atctaaaaac tcaccataac aattatcaac cattactata
    27241 gcttctggtt taacagactt tattacttct atagcttctt ttatatcact aattgaaagt
    27301 gattttctcc aagaatatcc ttttgacctt tgtatcataa cgagtttagt tctatcattt
    27361 attttgtttt taattccttc taaatctaag tttccatcct ctaaaaaatc tacatcatca
    27421 tatgtaacac catactcttt caatgaacct ttttcttctc ttatgcctat aactccctct
    27481 aaagtatcat atggtctacc agtaacagat aaaatttcat ctcctggtct aactatacct
    27541 tgtatacata aagtaagtgc atgtgtacca tttacaatta ttggtcttac aagagcatct
    27601 tctgtattaa atactttaga ataaatttcc tctatttttt cacgaccaat atcattatat
    27661 ccatatcctg tagtccagtt aaagtgcata tcacttagtt tagattcttg catagctttt
    27721 aaaactttat attgattata ttctcttatt tcttttattt cttcaaactt atcttttatt
    27781 tcttccatta tttcttgcga tagtttaaaa gtatcatcat ctattccata gtagtctttt
    27841 aataattctt ttgtctcatt aagcatttta tcacctgtct ctttattatt ttatttaaac
    27901 atgtaaagga gactatttta ctaaaacaaa taaattatag tttataagtt agtataagtc
    27961 tcctctcaat catcttaaat taaattaatt atctatctgt tgttattatt attgttgttt
    28021 tggttttgat ttgttagatt aatatacttt ccaggttgta tagttgatac agcatgttta
    28081 taaatcatgt tttgttgtct attatcccct tctattaata ttatataact atcaaacccc
    28141 tttacaagcc ctttaacttg cactccatta actaaatata tagtaacagg tatcctttct
    28201 ttccttgcat tatttaaaaa caaatcttgt aaatttaaaa ctgtattttt cattagattt
    28261 gtaccctccc aagattaaat tgaacttcta aaatattcct accttatatt ctatataagt
    28321 tatgacaaat tttcaatatt aagttgtata cttaaaaatt tatatattat tttatagaat
    28381 ctttaatata taagattatt tcatttttta attcgtctat attttcatat tggtctaaat
    28441 caaaccattt tgctgtttta tatcttttaa accatgttat ctgacgtttt gcataccttc
    28501 tagaatctct tttaattatt tcaatagctt cttcgtatgt atattctcca tccagatact
    28561 ttaatatctc tttataacct ataccttgca ttgatatcat atctttttta aatcccatac
    28621 ttaaaagttt ttttgcctct tcaaccaatc catttttaat cataatatca actctcatat
    28681 ttattctttg atacaaatgt tctctatctc tatttagaac tattattatt ggttgatatt
    28741 cttcattaaa ttttaaatca cttgaaaaat cattcatttt cttaccactt agacaaactt
    28801 caagagctct tatgaccctt ttagtattgt ttttatggat tctattagca gattcttcat
    28861 caagttcttt taacttatta tgcatgtaat ctattccctt ttcagcaagc tgtttttgaa
    28921 gttcttctct taattcatta ttggcatcag attgtgcaaa atccatatta tatattaaag
    28981 agtttaaata aagtcctgtg cctccagtta ctaaaacaca tttttccttt tcatttattt
    29041 catgtatata tttttttgct ctttgttgaa actctgaaac tgaaaatgga tagtcaggct
    29101 taacttcatc tataaggtaa tgcttcactc cttgcatctc ttcctctgta acttttgcac
    29161 ttccaatatc catatattca tatatttgca tagaatcagc tgaaattatc tctgcattca
    29221 tatcttttgc taattttatt gacaaatctg tttttccaac agcagttgga cctgtaagta
    29281 ttataagtgg tatttttttc ataacattcc tttccatata ttttaaatat ccaaatattt
    29341 tacataattc ttttaaacat tttttctatt tctgtcttag atatttcgac cattataggt
    29401 cttccatgag gacatgtaaa tggattctca cacttttcta gctgttccaa taaacttttt
    29461 atttcaatat cgtatatttt atcatttgct tttatagcag acctacatgc catagatgca
    29521 aatctctctc cttttaaatc ataattactt gtaatttctt ctatattatc aattatttga
    29581 agtataaatt tctcagtttc aggtactcca aatatagtag gaacacatct taccattata
    29641 tgattattgc caaaaatttc tagctcaaaa ccaaatttca taaataactc caagttattt
    29701 tcaatttgaa gcatatctat atttgatact tcaataacca ctgggtctaa aagtatttgc
    29761 atatttatat cttgtctata gaacttctcc atatatcttt catatagtat tctttcatgt
    29821 gcagcatgtt ggtccaacaa atacatagaa tcgtctttgc tcaaaattat ataagtatta
    29881 aatacaactc caattacaaa atatccgtat aaagaaaact tgcgttttga actacacaag
    29941 tattcttctt cactgtcctt aatactatct cctaagtaat aatttccttc atttttaatt
    30001 ccatcaactt gaaactcttc ttgtatatta tcatttgcac tatcttcact tagataatta
    30061 atgtttttta catcatcttc tacacttgca tttaggactt cacttactga ttgaaattca
    30121 tttattggtt tttcacttga taaagtaaca acttcaatga cttcatcctt acctttagta
    30181 atattactat ttttaggagt agattctaat aaatcattat ttcttaattt ataatctgta
    30241 cttttttctc tactgttaat agcgattcta ggttgtgttt ttttatcact ataagtagca
    30301 tattttccaa taagatttga gtgtattaat ttaaccttta aaaaatctct aagttctata
    30361 tacacttctt gttctttttc aaatttaatt tcaagtttat tggggtgtat atttacatct
    30421 atacatgatg ggtctacttc tatatttaag aagcacactg catgtttacc tattggaatt
    30481 atagacttat aactttctgt tattgcatct atgattattt tactttttac aaatctttta
    30541 tttatataga tatgttgtaa gtttttattt gaacggtata tattgttatt acctatatat
    30601 ccattcattt taaagtgatt gcacttaaac tctacatcta ttatattttc cgttatttct
    30661 tttccatata tacttctaat agtgtttaca agttttccat cccctggagt atttagcatc
    30721 tgtttattgt tatttgtata tttaaattga atgtttggat tacctattgc aagtttattt
    30781 atcaaatcac ttatgtttat agtttctgca tgagtagatt ttaaaaattt ctgtcttgct
    30841 ggtgtattaa agaaaatatc ttttataatg atggtagttc cattagtaga acctattggt
    30901 tctttcgata ttatttttcc accttcaaca tatattttag ttcctattat ttcatcttta
    30961 gttttagtcg tcatttctaa ttttgataca gctgaaatag atgccaatgc ttctcctcta
    31021 aaaccaagag agtataaatc atacaaatca tcaatttttt taattttact agtagcatgt
    31081 ctcaaaaatg atttttcaac ttcacttgaa ggtattccta ttccattatc tgtaatctta
    31141 attagacttt ttcctccatc aattatatct atggaaattt tatttgcacc tgcatcaatg
    31201 gagttttcaa taagttcttt tactacagaa gaaggtcttt ctacaacttc acctgctgct
    31261 atcttattta tagtcaaatc atctaggatg ttaattatat ttttcatttt tacacctcta
    31321 agattttatt tcttttgctt ttctttgaag attataaaga gagtttatag catctaatgg
    31381 agtcatattt aaaatatcca gatttaaaat ttcttctgat agtatatctc tatttacact
    31441 atcaaaagag atttgagtta aggctacttc ttttacagaa tcttcttgat taattttctc
    31501 tttatcatca ttttgcttca ttaaagcaac ttcatcattt aatgctttaa atttagaatt
    31561 taatttatca taatcctttt ttatatgttt gtagtctttt actataagtt catgttctat
    31621 ttttagagat tcatatttat tcttaaaatt actttgattt accttaacta attcttcgtc
    31681 caaattacta ttaattatat tattgttttc tttatctcca tttattgcaa cactgttgta
    31741 aacatgattt ttttccaagt ctttaagtat atattttgct ctttctatga cttcgtctgg
    31801 taatttagct aatttagcaa catatattcc ataactcttg tctgctccct gaggaattat
    31861 ttttcttaaa aatattattc cttccccatc ttctttgact gctattgaat aatttttaac
    31921 ctctttaaac tcttcttcta aatcagtaag ttcatgataa tgtgttgcaa ataatgtctt
    31981 acatctaata tttttttgaa tatattccac tattgaccat gctaaactta taccatcata
    32041 ggtactagtt ccacgaccta tttcatctaa tataactaaa cttctctctg ttgcattttt
    32101 taatataagg gatacttcgt tcatctctac cataaaagta gattgacctt gagataaatc
    32161 gtcactagct ccaactcttg taaatattct atctaatatt ggaatatcag cagactctgc
    32221 tggtacaaat gagcctatat gtgccataag agctattata gcagtttgcc tcatatatgt
    32281 tgatttacct gacatattag gaccagttat tatgttaata atgttttctc cacgatttaa
    32341 ataagtatca tttggaacga aattttcctc tcctactata ttttcgacaa caggatgtct
    32401 accatttctt atatcaagtt tattattttc atttattgct ggttttacgt agttatttat
    32461 atgtgcaact gttgcaaggg acacaaaaac atctatatta gctatagtct tagccacttt
    32521 ttgtattcta tctatgtttt tatatattgt atctcttatc tctacaaata tctcgtattc
    32581 taaagattta atcttttcct ctgcatgtag tatcttttct tctatttcct ttaattctgg
    32641 agttatatat ctttctgcat tactaagtgt ttgctttctt atatatgtct catctagctt
    32701 tgcctgttta aagttggctt ttgttatttc tatataatac ccaaaaactt tattaaatcc
    32761 tatttttaat gatttaactc ctgttttttc tctttccctg ttttctattt cctttacaag
    32821 aaaggctcca ttcttagaaa tctctcttag ttccttaagt tcatcactaa aatctgattt
    32881 aattatgttt ccatctttta tggttatcgt aggttcttct agaatagctt catctattaa
    32941 attgtatata tcatctaatt tatccatttc tgaaacatac tcttttagga tttttgcatt
    33001 tgataaattt atagtatctt ttaaattagg taacttttct atcgaatttt ttaagtgaat
    33061 taactctttt ggtgttactc tctcaaatgc tatctttcca catattcttt ctatatcgta
    33121 tatattttta agtatatcat ttaggtcttc tcttaatata aagtcatctt ttatttcttc
    33181 tattacatct aatctatttt caattttaga tttatttatc aaaggttctt ctacatattt
    33241 tcttaaaagt ctacctccca ttgctgtaga agttttgtca agtacatgta ataatgaacc
    33301 ttttttctta ttccctctta tagtttgagt aagttctaaa ttagttctag taaacatatc
    33361 tagaaccata tattctgatg aattgtatat atttatatta ttaatgttag atgttatttg
    33421 tttttgagta ttgtatatat aattcagaag aattgataag cttgacttta ttagaccttt
    33481 atcatcaaac tttagttttt gtagataaac atctggaaaa tattctttta atatatttat
    33541 atccaaatag ttatcactaa aactttcatt tatgtatata ttacttacag tagctatatc
    33601 tctaagcttt tctataaagt ctaaatcatt tataattatt tcagttggat ggatttttgc
    33661 aatttcttca attaccttat cttcatttaa acatgttgca ttagtttctc ctgtacttat
    33721 atcaacataa gttagaccta tattagtacc atccttatac aaagataata aataattatt
    33781 ctttttattt tcaagtaaat ttccatctaa aactgtacca ggagtgatga cccttataac
    33841 ctctcttcta acaattcctt ttgctgtaga tgggtcttcc atttgttcac ctattgctac
    33901 tttatatcca ttttcaacta attttgatat atatgaattg gctgagtgga aaggaacacc
    33961 acacatagga gcacgttctt ctaaaccaca agcttttcct gtcaatgcta tttcaagagc
    34021 ttttgaagct actaatgcat cttcaaaaaa catttcataa aaatctccaa gtctaaaaaa
    34081 cagtatacag tctttatatc tattttttac ttcaagatac tgtttcatca taggagttaa
    34141 tttattcata tctatttgca ttatcaaacc tccttctttt ctaattaaat attatatcat
    34201 agtagatgat tattattaac acaatatata aaattttgac atataactaa aaacaatcca
    34261 aaatgtatac tcacattttg gattgctaag tttaatgctt attaaataaa aatatttttt
    34321 tttacaataa agatattatt tcttttttaa gtttaatgat attttcaagg ttatcttcat
    34381 ttaactttct actatctata acaaattctt tctttactat tgatggtttt tttgaaataa
    34441 cataaattct gtttgatagc attatagctt cgtcaatatc atgagttata agaagtattg
    34501 ttgaatttac ttttttctta acatctaaaa gccatttttg catggatgtt ttagttaatg
    34561 aatcaagtgc cccaaaaggc tcatctaaaa gcattatgtc attagaattt ataaaagttc
    34621 tcaagaagtt agctctctgt ctcattcctc cagaaagttc tgaaggatat ttatcttcat
    34681 atccgcttaa tccaaacacc tcaaaataag gttttaccat tgacctagct ttactctttt
    34741 tttctttttt taaaattagt ggtagtgaca cattatctat tatagtttta tatggcaaga
    34801 gtaaatcttt ttgatacata taactatact taccatttat attcactttg ccactatcat
    34861 aatctgtaag tttagttata atattaaaaa tagtactttt tccacatcca cttggcccta
    34921 atatagaaac aaactcacct tcataaacat caatacttat atcttttaaa acttcaatat
    34981 ctttataagt ttttgataca ttttctatag atacttttac ttttttattg tggtaaaaat
    35041 tcatttgtgt aagcatcact tgccttcata tccttatcta ttaatttata ttcttttaag
    35101 aatgatgtat agttgttcca tacactatct ttcatttctc cccatcgtgg tgcatcatct
    35161 ttgtacttgc ttgctaaata ttcttgactc tttaaagcta gtttttcatc tacttcaggt
    35221 gcatgtttta ctaaaatttt tgctgattct tctggatttt ttattgcata ttcataacct
    35281 tttgttgtag cttttaagaa ttttttagca agctctggat tatttttaag cacagtttca
    35341 ttagaaatta taagtggtgt ataataatcc aatctctcat ctaaatcttt tactggtata
    35401 aagtttaagt catatccaat taaatcagct ttaactgcat cccaaccttc aaatatccat
    35461 gcaaaatcta cagttttcat agctgcaaag aaatcatctt gaccagtatt aactatcttt
    35521 aacttattaa aatcagctcc atttttcttc ataactgctt taaaaacagc ttcttctgat
    35581 ggagagcccc aaccaccata agtttttcct tcaaaatctt tagctgttgt tatattcttt
    35641 tcttttggtg atgcaaaccc agaagtatta tgttgtataa cagttgctac agcttttatt
    35701 ggaagtggat cttcactagt ctttgcataa gtaacttgtt cttgatagct tataccaaag
    35761 tcagcttttc ctgttgctac taaagtttct gctccacttt caggtggttg tactatttca
    35821 acatccaaac cttcttcttt atagtaaccc ttatcaagtg ctacaaataa tccagtatga
    35881 tttgtatttg gtgtccaatc aagcaccata gttacttttt tagaagaagt atctttatca
    35941 ttgtttttgt ctttattgtt atttgaagaa catccagtta ttgttgccaa tgtaaaaaca
    36001 cttactaaac ctaatattcc taacttttta aaattcataa ttgcctccct caaatacctt
    36061 taatctatta atctatgtct tataacaact ttttttacag cctgtacaat tcctacaaac
    36121 attaaactaa atataactac taatatagta gatgcaaata ctttatcaag tgcatatgca
    36181 ctttttgacc taagcatata aacaccaagt cctttcgttc cacctagcca ttctgcaaca
    36241 gttgctgcca ttacagcata cgttgcagat attttaagtc cagaaaaaaa tttatccatt
    36301 gccataggaa atttaaggtg aatgaatgta ttaactttat ttgagtccat agtcttaaat
    36361 aaatttaaat aatctttatc aatattctca atgccatcta caaaacttat taatatagga
    36421 aaaaaacaag taagcattac catcaatact tttggcattg ttccaaatcc aaaccatatc
    36481 ataaagagtg gtgctataat tattgtaggt atcatctgtg taaccaacat aataggataa
    36541 agacattttt ttattattga tacaaaatcc atcaatattc caattaccaa tgatattata
    36601 attgcgacta taaaaccaag tattgcttct cctatagtaa ccacagcatg tatggataaa
    36661 ttttgataat ctttaaaaaa cacattaatt atatctactg gtgtgggtag tatatactga
    36721 ggaacttcta aaactcctac catagattgc caaagaataa gtataaacaa aaatgttgct
    36781 attggatata tactatcttt gactttatct atgatttcta agtttttcat ctatagtcag
    36841 acctccagct ttttcatcta ctctagctac tgttatgact ctttcacatc caagattaaa
    36901 agggatttta tgtacctttt ttaataattc aaaaacttca tcaaaatcac cttcaacagt
    36961 agtgctcatt gctcctattt cacatttaag accacttttt tcaatttcag caatacaagc
    37021 atctactact ttatacatct cttcttcacc tttgtaaggt cttagtggca ttactgctat
    37081 gtctgcgatt accatttaaa tcactccttt aaaaataatt aatacctact aggtatattt
    37141 tgttttttat taaaaaattt tattactaaa aagatattat atttaaataa aagaaaagtc
    37201 ttatccaaaa taggataaga cttattttta tcttaactgg tctccctaca ctggcattat
    37261 ccaaacaggt tcaaagggtc gagataaaat ctcctctcag cacattagct ccccgaaata
    37321 tattatatct tttctacttg attatactac acttatcata ttttaacaaa ttttttattt
    37381 atattagata ttttatccgt tcaaaaatat ctaatataaa ttgtacatta ttacaccaaa
    37441 taaattatct taaaatggta atttatcaac atcttccaaa actagattaa ctgaattttc
    37501 tagtttttat tttgctattt caagcatatt tggatgtata tcaattccat acaaatattg
    37561 tgctaaattt ctgttttcac tcatctaatt tgcaatcgtt acaaattaca gattagaaat
    37621 agcttttaga ctctacttat ctttatctac aaaaaatcct tcaataaatt cattaataat
    37681 attcagtaat ctaaaaataa acctctatct agatttttaa gatacaagcc ttttaggaag
    37741 tatcttttgt gataatataa aaattactca tcattatcat caaaatcctc agcaaccaac
    37801 attttagata agaatcaaac tctataatat aattatttta tccaatttat ttttgagaaa
    37861 taaaatattt ttttaatttt taaatttttt aatatgcacc ttgaaaaaag aaacgttttc
    37921 ctatattatg gtaatagtag aataaaacta aataggcaaa actagagaaa tttagtgacg
    37981 caaagctata gggactaaga cttatgaaat gagttatgtc agccagttgc caaagagata
    38041 ttttcttttt gtttttatga atgtttttta gggggatata tgatatatgt ttatggataa
    38101 aatggataga tgtacacata tactaactgc atatatatgc agttcacgcg attactgcaa
    38161 ttttatagat acacaattaa atgattttat actagaatat ggagagaatg tggtagaatc
    38221 ttgtttgcat caagtgatgg tattggtaag cagatataat taaagaaatt ttattttcta
    38281 gaaaaccctt tttagtttta tctacgtttt ataattcatt aaagaactaa ttaaaataag
    38341 cttcattata tatttttcat aaagtaaaca gttgagttta tctcatatac tgtttacccc
    38401 aattacataa ttctaataat atagattcta atgatttacc acgtttagta gacaaatatt
    38461 caacttttgg aggaatagtc ggataagaaa tcctcttaat aagtccatct ctttcaagat
    38521 actttaattc ttgtgacagt atcttatgac ttatatgaac aacttctttt tttaattgac
    38581 tgtaacgtat tggctcttgt tttaaaatat gccataaaat aattgccctc catttacttc
    38641 ctatcacagt catggtaaaa ccaattgaac aattaaaatc tttttgtctt tcttcaatat
    38701 ttggaaattc ttcaaaatta ttatctatat ccatctcaat cctctctttc aaaatagtaa
    38761 gtatctaact aaaaagtgca ttcttgttta gcgtactaat tcgtaatata atcttgattg
    38821 tagtatagag ccttacataa tactactttt ttagatgtat atgtttaaac tttaatatag
    38881 acatatgtta ttttattaat tttatttaaa cagataataa taaataataa tttatctcaa
    38941 gttttctatg tagataaact aatctaatgt ttagaaagga ttatataata tgaataaaaa
    39001 atttcgtctt tatcaagttg actcattaca aaagaaaaat ttacaggtaa tccagctggt
    39061 gtaattacaa atgctgatgg cttatctgaa tcacaaatgc aaaaaatagc aagagaatta
    39121 aataattcag aaactgcttt tattttcaat aacttggcta aaaatcatca agaaaattat
    39181 gatgtacata tcagattttt tacactaact aatgaggttc ctatatgtgg tcatgctact
    39241 attgctgccc attatgttag agcagtagaa aaccaattca ataacaaaac agtatttcaa
    39301 aaaactagtg ctggaatatt accagttgat attataaaaa aagataatga ttatgaaata
    39361 attatgacac aaggaaaaat tgaagtatct ccaccgttac aacaaaccta tcaaaaaaga
    39421 ttacttaatg catttggtat tttaaaggaa gatattcgta cagattgtcc tattgccata
    39481 tcatctacag gacattcaaa agttatgatt ggaataaagg aattatcaac attaaatagt
    39541 ttatctccaa atttatatga attatcgaaa ataagtcaag aaataaaatg taatggatat
    39601 tatattttta cattacataa taaagaaact ctacaagttc atggaagaat gtttgctcct
    39661 gcaattggta tttcagaaga ccctgttaca ggaaatgcta atggaccctt aggtgcgtac
    39721 cttgtacatt ataaagtaat acctacaccc aacacagagt ttatatttga agcagttcaa
    39781 ggagaaacaa taaaacgcaa aggcaagatg ttagtaaaag taattatttt agataataaa
    39841 ccagttgaag taaaaataat tggaaaagct gtaattgcat tctcaacaaa catagaaatc
    39901 taattataga ttccttctaa gtaaattttt gaacttttta atactaattt aataacaaac
    39961 taatttatat acaatcaaat taattttttt attatttg
//
LOCUS       DAMJVG010000034        39398 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.034, whole genome shotgun sequence.
ACCESSION   DAMJVG010000034 DAMJVG010000000
VERSION     DAMJVG010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 39398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39398
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.034"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            57..446
                     /locus_tag="PC512_001859"
     CDS             57..446
                     /locus_tag="PC512_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2441601.1"
                     /translation="MVLNLDFNSDKSIYVQIKEEITKAIASGELKINESLPSVRSMAE
                     NIGVNLHTVNKSYNELKEEGFLNIDRRKGAIVAQLPMKIDNTTRQKNKLDLELLVAKS
                     YLSGISKEEFLSLSSSLFDKYEVKYYE"
     gene            439..1530
                     /locus_tag="PC512_001860"
     CDS             439..1530
                     /locus_tag="PC512_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1648 domain-containing protein"
                     /protein_id="HDF2441602.1"
                     /translation="MSKIECLFTIFPVLILMYATFYFMPYFVGKKHIYGVSIDQEHKN
                     YNYFIKLDKEFKKLLSLGFIIDFILVFILVFTFNKLELSYFIGIIGFLLYESILYIHT
                     HKKAKKLKSEIYSKLGHIDIDSKLIVDMDFINKKNKIIKKFKIIYLIPILFTLGMSIF
                     IAFNYNQLPDSIATHWNINGSPDVFIDKSFLNVFKLIGTDFCLMVLLYITSIGSIKSR
                     IKIDTNRIEESRVENIKYLNKIGYLFLILMIIMTTQFFTTLLSIKTKLSTAMNITTLL
                     VIIYLIATYINSPNLKFNSSYSPEEDEKYWIAGIMYNNPNDPSLMVNKRFGIGWTINF
                     GNPLGKILYIAIALLLIFSLFSLIKSLLL"
     gene            1650..2126
                     /locus_tag="PC512_001861"
     CDS             1650..2126
                     /locus_tag="PC512_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HDF2441603.1"
                     /translation="MLSKAEIKYFNECASEILSSEKVQLMRTFPHHGNVSCLEHSLSV
                     AYYSYLLCKKLHLSVDIQSVIRGALLHDFFLYDWHYKGDRKGLHGFTHPREALKNATL
                     FFQINEKETDIILKHMWPLTVKPPRYKEAFIVCLLDKFCCLVETLKIHSLLSPYHV"
     gene            2512..2979
                     /locus_tag="PC512_001862"
     CDS             2512..2979
                     /locus_tag="PC512_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HDF2441604.1"
                     /translation="MFKEMRLKKREMTKEDTVEVLKNGEFGTFSTISENGYPYGVAVN
                     YVYFNDSIYFHCARNGHKLDNISKNNKVSFLVVANESVIPDKFSTTYSSAIVFGKACT
                     VENEEKKNALVEIIKKYSKGFFEEGMKYIEKDMNLTTVVKIEIDHISGKASRL"
     gene            complement(3039..3611)
                     /locus_tag="PC512_001863"
     CDS             complement(3039..3611)
                     /locus_tag="PC512_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HDF2441605.1"
                     /translation="MKVAVIFHSVCGSTYLLAREYKEALEEMNIEVDIFRVSDEVAKT
                     LPQYYLINSKEYKDEFESINVIKSGKEILDYDAIFMGSPTYYGNVSGPMKMFMDSFSD
                     IWVGTPLSGKIFGCFATAGSQHGGGELALQAMNIFAQHMGMTLLSVPCSVRGGYPAYG
                     ILHIAGDNSDIRPNDDAKIGIRDYLKRLNI"
     gene            complement(3674..4771)
                     /locus_tag="PC512_001864"
     CDS             complement(3674..4771)
                     /locus_tag="PC512_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HDF2441606.1"
                     /translation="MLLKSLTRKIEKKYPLNLAEDWDNVGLIVGDFDMDVKKVLVSLE
                     ANEDVIDEAISKNIDLIVTHHPFIFGKINKINSGDLKGRLIQKLIKNDISLYSMHTNF
                     DIAFDGLNDYFMEIMEFGNSKVLDITKSENLYKLAVYVPHNYSDELRKVLSNSGAGHI
                     GNYSDCTFSIEGEGQFKPLEGSNPFLGSVNDIETVNEVKIETVVPQKLLGGVISSMLD
                     AHPYEEVAYDLYKLENKGEIFGLGRISKLDKSMTLESLSRKIKEKLNMKHIRVVGNLS
                     TDITKVAVVTGAGSEFVKKAKRQGAEVLITGDVKYHEAQDALDIGMCIVDCGHFDTED
                     IFKNVMKRFLDEFSEIEVIKSNVYLNPFSTI"
     gene            complement(4785..5474)
                     /locus_tag="PC512_001865"
     CDS             complement(4785..5474)
                     /locus_tag="PC512_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HDF2441607.1"
                     /translation="MKLTDRLLKIASLVSDGKKIADIGTDHGYIPVYLLKEGKVPFAV
                     LADVNKGPLDNAHKEVIQNNLLDKVDLRLGSGIEILEIGEVEEVIIAGMGGILISELL
                     EAKKEVAHNVEKLILQPMQAQEELRYYLLNNGYEILEEVLVREDFRIYEIIVAKYTGK
                     NTIIEDEIYYEVGIKLLENKDSLFNDFIEKKIKTYSSIVNKLEGKNGEAIDKKRKESE
                     VAIKKLENLIK"
     gene            complement(5639..6805)
                     /gene="rpoD"
                     /locus_tag="PC512_001866"
     CDS             complement(5639..6805)
                     /gene="rpoD"
                     /locus_tag="PC512_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HDF2441608.1"
                     /translation="MENKSNKKELKKVTAKTLIEKGKKQGSLTLAEIMEAFSETELDK
                     DQVENLYETLGNLGIEITETKNYKADIDFSVADDDLSIGHLDEDAEAISHDDSSAIEI
                     ETVDLSLPKGISIDDPVRMYLKEIGKIPLLKPHEEVEFARRMHEGDEIAKQRLVEANL
                     RLVVSIAKRYVGRGMLFLDLIQEGNLGLIKAVEKFDYTKGYKFSTYATWWIRQAITRA
                     IADQARTIRIPVHMVETINKLIRVSRQLLQELGRDPKPEEIAKEMEMTEDKVREIMKI
                     AQDPVSLETPIGEEEDSHLGDFIPDDDAPAPAEAAAYSLLKEQIEDVLGSLNDREQKV
                     LKLRFGLEDGRARTLEEVGKEFDVTRERIRQIEAKALRKLRHPSRSKKLRDYLD"
     gene            complement(6823..8613)
                     /locus_tag="PC512_001867"
     CDS             complement(6823..8613)
                     /locus_tag="PC512_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HDF2441609.1"
                     /translation="MNDIKDIIEEIKARCDIASIISEYMNIKQSGANYKGLCPFHGEK
                     TPSFYINTSKQIYKCFGCGEGGDVINFVMKMENLDFMDAVKILANKCGIEINTNMNEE
                     TRIKIEKSKKFQDIHTEAARFYLSNLLGSKNLGYEYLRIRGLDDKIIKKFGLGFSLDS
                     WNSLMNTLISKGYKKQDLLECGLIAKNRDGTNCYDKFRNRVMFPIFDYRGNIIGFGGR
                     VLDDSLPKYLNSPDTLIFNKKQNLYGLNFARKNLESKTIVLVEGYMDLISLYQYGIKN
                     VVATLGTALTEQQGILIKRYADTAIISYDSDEAGIKATLRAIDILTKLGINVKVLDLK
                     DAKDPDEFVRKYGLSDYKKAMDVSTHYIKYKIDHLKKEFNIQKDEERVKFAKEASKII
                     KQLTSPVEIDFYTKYLSNQIDINVESIKREVYGKNYNKPYNNKNQKKIEEKVIEKVEV
                     RQDGKQLVEETLIKIMLEDKKIREIALLKVEESDFLLKESKEILNYMIKNQELDKITI
                     DKLKSLNISEEYLKELNSISLNSINLENTKEIEGIITNIRKNSLEEQINSLLREQQEL
                     ENNNDMKEVDGRVMEIALKIVEINKILKSL"
     gene            complement(8868..9653)
                     /gene="aroF"
                     /locus_tag="PC512_001868"
     CDS             complement(8868..9653)
                     /gene="aroF"
                     /locus_tag="PC512_001868"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HDF2441610.1"
                     /translation="MKENLFNNNSKIEINTNNKKITVKKDKLIIAGPCAIESYEQLLE
                     TAKFVKSQGANILRGGAYKPRTSPNSFQGLKKEGLEILKAVKDEVGMAVITELMDVRD
                     MDELYSISDIIQIGSRNMQNFTLLSEVGKQNKPVMLKRGIASTITEWIGASEYIAIEG
                     NSNIIMCERGIRTYNDYTRNTLDLAAVPIIQKETGLPVVVDPSHATGVRYLVKPMSLA
                     SFACGADGIMVEVHPDPENALSDGAQSLCFNEFEDLMKSINNY"
     gene            complement(9634..10140)
                     /gene="folK"
                     /locus_tag="PC512_001869"
     CDS             complement(9634..10140)
                     /gene="folK"
                     /locus_tag="PC512_001869"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HDF2441611.1"
                     /translation="MNKAYLGIGTNMGDRFDNLSRACELLKNSDSIYKVKESSLYETK
                     PWGYTEQADFLNMCVEIETEFEPYELLEYCQEIERELHRERIVHWGPRTIDVDVLFFN
                     DVVSTDERLTIPHPRIQDRAFVLIPLMDLNEELIINEKTIKEHLNLLSAEEREEVKEL
                     VGYERKPI"
     gene            complement(10133..10498)
                     /gene="folB"
                     /locus_tag="PC512_001870"
     CDS             complement(10133..10498)
                     /gene="folB"
                     /locus_tag="PC512_001870"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HDF2441612.1"
                     /translation="MDKILLSNLGFYGYHGVLKEENFLGQKFFVDMELYIDSREAGLS
                     DDINKSVSYAEVYNVVKDITENKQFNLLEALAENIAEEVLNKFILINGVMVRVRKPEA
                     PVNGIYDYFGVEIRRTRDE"
     gene            complement(10509..11300)
                     /gene="folP"
                     /locus_tag="PC512_001871"
     CDS             complement(10509..11300)
                     /gene="folP"
                     /locus_tag="PC512_001871"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HDF2441613.1"
                     /translation="MFDYGKRTYIMGILNVTPDSFSDGGDFNNLDIAIQHAKDMVDQG
                     ADIIDLGGESTRPGHSYVDSDEELRRVIPVIKKLKQELDIPISIDTYKADVAEEALKL
                     GVTMVNDVWGLRKDKNMASVIGKYDAEVCIMHNQDGTNYDKDIMESIKDFFKVSIEMA
                     MSCGVKKEKIVLDPGVGFGKDFEQNIEVLRRLNELKDLGYPILLGTSRKSVIGKVLPV
                     EPKKRLEGTIATTVLGIRDGVDIVRVHDVYENLMAARMTDAIYRK"
     gene            complement(11364..11936)
                     /gene="folE"
                     /locus_tag="PC512_001872"
     CDS             complement(11364..11936)
                     /gene="folE"
                     /locus_tag="PC512_001872"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HDF2441614.1"
                     /translation="MNKVDKEKIQHAVREILEAIGEDPDREGLIETPNRVARMYEEIF
                     SGLSEEPRDHLKVLFADEKHEELVLVKDIPFYSCCEHHLVPFFGKAHIAYLPKGGRLT
                     GLSKLARVIDTLAKRPQLQERITKNAADIIMEELQPYGVLVVVEAEHMCMTMRGVKKP
                     GSKTVTSAVRGIFEKDIASRAEAMSLITMK"
     gene            complement(11962..12663)
                     /locus_tag="PC512_001873"
     CDS             complement(11962..12663)
                     /locus_tag="PC512_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441615.1"
                     /translation="MIGCIYEVYNEEMTKIIENQNTLAVYLVGSSKDVDFTLYDVVIN
                     DIDVFVFVKEGEKQERILFKKKGIEFDVNYFSKDGVKKLLSNREYFFVKEMKDAKVLF
                     DRENISHIIKDISRDIYLEGPSKMSLEEKSFIKQDIGAKILNLKNKEKFDVFEYHFLT
                     NLYLKDIIIGYFNINDKWVPKDKKLLKVLKKENNELFELVSKVSENYDYQRLLDVYNY
                     IFKEIETKEVIKLIF"
     gene            complement(12697..13440)
                     /locus_tag="PC512_001874"
     CDS             complement(12697..13440)
                     /locus_tag="PC512_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class IV"
                     /protein_id="HDF2441616.1"
                     /translation="MKNNVGFDSSLSKFGIGLFETIRVKNGIAVDLDIHIERMLSSIN
                     CLDLDINYKKDFLINEIVTYIKKENVINKALRITVFDEGYNISIRDIPYNQETYEKGF
                     KLAISPIVRGNSLIHRHKTTNYFENIYTKNIANKTGYNDGIFLNSEGVILECSMSNIF
                     FIKGERVYTPSDRLPILNGIIKKRIIEICDELHIELIENEINISEISSFDFVFVTNSL
                     MGAIKVTEIDKIKFNKENVVFDKIVKLLE"
     gene            complement(13430..14779)
                     /gene="pabB"
                     /locus_tag="PC512_001875"
     CDS             complement(13430..14779)
                     /gene="pabB"
                     /locus_tag="PC512_001875"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HDF2441617.1"
                     /translation="MIREINTKLNSFEIFTIFRNEHDSFILDSAMDKEKLGRYSFISS
                     QPFKVLKYKDTDENPLEVLKEELHKYRVVNDTNLPFVGGAVGYLSYDLGNYIENLPRT
                     AVDDIEMPDMYFGFYNHVIVIDHLVQKTYIATPNIDIELEEKIIDDIEQRILKEEKKG
                     IDSICYEEKEVTPIRLKSNFTKEEFKNAVQSVREYIRQGDIYQANLTQRFSGETELTS
                     FELYRDLRRFSPAPFGAFLNFEDAHILSNSPERFIRCVNKRIETRPIKGTRPRGKDKE
                     EDLRLQQELRNSEKDRAELLMIVDLERNDIGRISKTGSVKVPELFVIEPYANVNHLVS
                     TVVGELKDDKDATDVIKATFPGGSITGAPKIRAMEIIDELEPTQRNVYTGSIGYIGFN
                     GDMDFNIAIRTIIKNDKKVYFQVGGGMTWDSDPDEEYQETLDKAKSIMKALRGYYEE"
     gene            complement(14781..15365)
                     /locus_tag="PC512_001876"
     CDS             complement(14781..15365)
                     /locus_tag="PC512_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HDF2441618.1"
                     /translation="MILMIDNYDSFVYNLVQYIEELGEAVVVKRNNEIKISDIEELNP
                     EVIVLSPGPCSPKEAGICIDIVEHFKGKKPILGICLGHQTIGHVFGGDIIKAQQPVHG
                     KVYSINHTNKGVFRGLKNPLNVTRYHSLIVDSNTVPKELEITAITDKGEIMGIRHKKY
                     LIEGVQFHPEAILSEYGHEMLKNFITEARERVHM"
     gene            complement(15389..16108)
                     /locus_tag="PC512_001877"
     CDS             complement(15389..16108)
                     /locus_tag="PC512_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDF2441619.1"
                     /translation="MTSWKKKTVYKCLIAVALFCGIVLISNFSKVSALMMDTNGNVLI
                     KHGSREKKLIAITFDDGPHPKETSQVLDVLKKYNVKATFFIAGKHAKWYKEPLVRASK
                     EGHEIGNHTFNHPDISNLSSSQIEEEIVKCEDILKEVTGKKPTLFRPPFGSYREKDLI
                     EIAKKHDYKVVLWTGVDVKDWKNPGANSIADKIINKVQNGDIILLHDYATNDTVEALD
                     MFIPKMIEKGFKFVTVSELIK"
     gene            complement(16136..17200)
                     /locus_tag="PC512_001878"
     CDS             complement(16136..17200)
                     /locus_tag="PC512_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HDF2441620.1"
                     /translation="MKRLIALVLVVLIVLFYSPELLKEGYDLKEKFFQSEIWNEFLDK
                     ININDNSKKDKKEKSQNLQSNNTEGENLGESDIKNFEKISLGDNLSYVLSSIGKPGRI
                     DISEYGFDWYVYNQYGKEFAMVGLENDEVVALYSNSINSCENQDIKLNQDRQTVRTKI
                     TPLKYKRKGNTRYIINSENQYDIISKEGKYITIFYDIHEENRVCSYLIIDKSTEDEFK
                     NLYPDDSEELKKCFELEVIDLVNSVRNQRGLNSLRYSEQATLSSRKHSEDMRDNNFFD
                     HVNKKNETPFDRMKREGIVYTSAGENIAAGQINAIYAHEAWMNSEGHRKNILGNYNNI
                     GVGVIFGGSYKTYYTQNFYK"
     gene            complement(17344..18153)
                     /locus_tag="PC512_001879"
     CDS             complement(17344..18153)
                     /locus_tag="PC512_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441621.1"
                     /translation="MNLSKEYVNLYDNYLKYINEVNKEIRSIKNMKKRVLKRGDFAPE
                     NEVLELEGKTIRDIDDVDTKKPKNKIYKFSNGDVYVGKFLEGKMEGKGSYTFFVDEGT
                     VMEYIGEFKEDKKNGKGNFIFSNGNEYIGYFEEDMMSGIGNMLYSSKDEYIGTWKNGK
                     KDGKGIYKWSDGCIYAGEFKGGKMEGYGICYNSKGEVLYEGEWKNNLIHGKGTYIWEK
                     GKKYIGEFMHGKKHGQGTFYLNNELVYEGTWKFDKPSIFDRTLDEIFSLRL"
     gene            complement(18395..19261)
                     /locus_tag="PC512_001880"
     CDS             complement(18395..19261)
                     /locus_tag="PC512_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDF2441622.1"
                     /translation="MSEVKNTLQKHPVLRYSTMLFGMLMTSIGINGFLRPAHLLSGGA
                     TGIATSINYLTNINVGLLTFLINIPIFILGFIYLEKEFCISSLVNMIVFSLLLGATQE
                     ISNIIPIHDILLQSVYGGILSGLGVGVVFRTRSSQGGTDIIAAILKIKKNIEMKDTAL
                     AINGLIVLTGSFLFGLDLALYTLIGLFLNAYSMSFIKDAMNYQKSVMVMSNEVDLIAE
                     DIMKSLVRGVTFLDAEGAYTHQKKKIIYTIVSSNEIPKIKDIALKYDKKAFISVNDVT
                     EVKGRGFKAKDL"
     gene            complement(19781..20470)
                     /locus_tag="PC512_001881"
     CDS             complement(19781..20470)
                     /locus_tag="PC512_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HDF2441623.1"
                     /translation="MYNVLQTPVFGIIVTIVFFNLGRYIQRKTSNPICNPLLIAIVGI
                     ILFLSISKIPYENYKIGADSLNFFLGPVTVVLAVPLYKQFELFKKHMFEIIVGIGCGI
                     VISFVSVLIIGKIANSDVSIINSLIPKSITTPMGISLANSLNGVESITVVAIIFTGIF
                     GGMVASTVFKLGNINHPVAKGIALGTSAHALGTTKAFELGEIEGAMSGVSIGVSGTIT
                     VILIPIIMNFI"
     gene            complement(20463..20834)
                     /locus_tag="PC512_001882"
     CDS             complement(20463..20834)
                     /locus_tag="PC512_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HDF2441624.1"
                     /translation="MKVFNQLVIILSIWVIGEYISSFIQGIILIPGSIVGMLLLFLLL
                     QFKVLDLSSIENVSGFFLDNMAIFFIPAGVSLIKSLDLIRENVLVLLLVICLSTLIVM
                     YTTGIIVEKMIKKKEEGQKNV"
     gene            complement(21016..22362)
                     /locus_tag="PC512_001883"
     CDS             complement(21016..22362)
                     /locus_tag="PC512_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HDF2441625.1"
                     /translation="MPRKILDISLIEDNKSDLTFFNIEEEDGDETLKALKQSYVTTNY
                     KEETLLNLQGALNSKSDTTSKELKLESYKRYNNALDLAYKNYITSAINMVNKALEINP
                     KDIDILNLRGLLKLLKCDFAKSFESFYTALCYENNHISRKYVNLISSEDFKTFLGRYN
                     HSIRFINEELNYESIHILENIIEEEPELIEPYVILSLLYDKLGNVKKREGYLDKLKEL
                     DKDNPVFEKNEEEKEDTSKKEEIKKVKRKKSILPYIIVGCVLIGMGIYLIQSKKRIEN
                     LNNQISSKEEKLSETDKKLGETSKKLEKTNKELNEVKNKEPEREITVADEEDLYYQAL
                     NLKKNKEYEKAIDNFKSVVSSGKTKKYISESIYQLAITNKLLGNKDEAIKYYKKYINT
                     YTKNDQYYDDSYYELGMFYYDNGDLKNAQQTFYSLRSEVPDSMYNNSKIKEILSEK"
     gene            complement(22544..23137)
                     /locus_tag="PC512_001884"
     CDS             complement(22544..23137)
                     /locus_tag="PC512_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fis family transcriptional regulator"
                     /protein_id="HDF2441626.1"
                     /translation="MNLNNITNYVQSICENISNVLDVDVTLVTKDLTRIAGTGIFRGK
                     IGETISEKSVYSLVLKDGKSYVINKEIEENCNKCANRENCKELADICTPVKMGEHILG
                     ILGIAAFNEEQKEKILSKDKELTAFVRSMSDLISFKLDELYKQEVKTIDDLEREAIEN
                     AIKKYGSNTEGMKKVAEALNIGIATLYRKVKKFNIKS"
     gene            complement(23202..24671)
                     /locus_tag="PC512_001885"
     CDS             complement(23202..24671)
                     /locus_tag="PC512_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HDF2441627.1"
                     /translation="MSNVNKKLVIAIGAVALVVIIFIGIMCMQFKGEKIAKNTYVNGV
                     NIGKLTKSQAKQELAKKYKLENVDFNYNDKSWKVKSKDLNLSTDLDKTVENAYNLNRK
                     SAFFGNLSKTISANFGKKSNLVVAINYDKNKLKAEMEKIAKEIDVDVKDATLDISGEK
                     VKVIPDSDGLKMDISKSMENFDNQTKKGNYKNELVVKATPAKVKKEQLANIDTNLGTY
                     STTFKTSQINRSINIKLATDNISNVLLMPGETFSFNKHTGKRSKENGYKSAPVIMEGE
                     MEEDYGGGVCQVSSTLYNSVLYAGLEIVNVKNHTIPSSYVPKGRDATVADSGIDFLFK
                     NNLKHPVYIKNYVSGNQIVCNIYGSAEDKQNITISTKLDGVSQTTMKRVNDPTMPKGK
                     EKVDKSGRNAYSVSTYRTFNDANGKKIKTEKIANSYYPKKEGIILVGTMEPKPEEKPN
                     TDENKNNQNTNNQNPNNQQKPETPPTDNKPNETQPQPQA"
     gene            complement(24786..26177)
                     /locus_tag="PC512_001886"
     CDS             complement(24786..26177)
                     /locus_tag="PC512_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HDF2441628.1"
                     /translation="MNFRDLFEKAVDFIDEKRKSIVAISLSTLGVIALIIVFFLSSNE
                     FSVGNEANELLKIIEKRQYSIAVDYYTSIEKKFSDSKMERFNKSVSKKINKLLLNSGD
                     KYLDGDISQESFIGLINTVKELNKISIDVDDLLAQADRVREMYKEENTTYDIAINYIS
                     TVSILNGMGSNLDVYKQNIETIKESRDVYDSAVKDQKAYKYYEAIEKYNKVLKEDEKY
                     YSMAQNGKEQCIEEMYDYYISRAEEANTSGDYERALQYIEYLKDDYSDDEKVQSLEKK
                     YKKNLSLYTLTSDDIINVIAKKSGKDKANLSINSLPQMIKNNKYYYAEVYEYDKLINE
                     VLVSAKTKDLYSYKDGKKDYKVDYGDGYFRILEDGSYQFGITKDKAKFVLTNTLDEKE
                     NKYKKIEILDIEKADRYVKSKKSLEELFGKYKNIYYYAVVNKGLFRGKEVYAINIYNE
                     KIYAISENGLNEY"
     gene            complement(26343..26591)
                     /locus_tag="PC512_001887"
     CDS             complement(26343..26591)
                     /locus_tag="PC512_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441629.1"
                     /translation="MMICFAMTFALVLINSVMGVHIGLDYYFLMGSVLTVCLTIGIVL
                     CNARKIFDSKAIHKTRTKTVSNNKKQKSHSRDIKRKIS"
     gene            26857..28986
                     /locus_tag="PC512_001888"
     CDS             26857..28986
                     /locus_tag="PC512_001888"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HDF2441630.1"
                     /translation="MPNLPSLGSKAPDFKANTTNGPIRLSDYKGNWIVLFSHPGDFTP
                     VCTTEFLCFAKYYDEFKKRNTELIGLSVDSNSSHLAWMYNISLLTGVEIPFPIIEDRD
                     MRIAKLYGMISKPMSDTSTVRSVFIIDNNQILRTILYYPLTTGRNIPEILRIVDALQT
                     SDRDNIVTPANWFPGMPVILPYPKNYKELKNRVNSCNKKYSCMDWYLCFVPDNYNDEE
                     VSKKIDNTCSWKKEHTKNIENECNCEHEHHDYLNKALDCKQEHKTDIKDDCNHEKKHT
                     KNTNKVHNSKQDKFKDKSCDEMNFNYDKDESCDKINSSYNKEDSSYEDFYKHNYKNYD
                     YTSEKNTKKIAMKTLKDSKKLVRPQITDPYNPIVENANCPDINPIVAEYVLGNPTNVD
                     AQLLDAVIFAFAEIDQSGNLFIPYPRFLNQLLALKGEKPSLKVIVAIGGWGAEGFSDA
                     ALTPTSRYNFARQVNQMINEYALDGIDIDWEYPGSSASGITSRPQDRENFTLLLTAIR
                     DVIGDDKWLSVAGTGDRGYINSSAEIDKIAPIIDYFNLMSYDFTAGETGPNGRKHQAN
                     LFDSDLSLPGYSVDAMVRNLENAGMPSEKILLGIPFYGRLGATITRTYDELRRDYINK
                     NGYEYRFDNTAQVPYLVKDGDFAMSYDDALSIFLKTQYVLRNCLGGVFSWTSTYDQAN
                     ILARTMSIGINDPEVLKEELEGIYGQF"
     gene            complement(29243..29842)
                     /locus_tag="PC512_001889"
     CDS             complement(29243..29842)
                     /locus_tag="PC512_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease H family protein"
                     /protein_id="HDF2441631.1"
                     /translation="MAKQKFYAVKKGKNIGVYNTWDECKKQVNGFSGAEYKSFSTFQE
                     AKEYIDGSEKLSFQEDKEFIEAYVDGSYEHSVKMYGSGVVILKNNEVIKTYSEKGKEK
                     TLVSMRNVAGEIEASKIAMQYCIDNNVQNLILYFDYEGIEKWCTGVWKTNKEGTIAYK
                     NFYDSIKNKLNVKFTKVKAHSGNKYNEEADKLAKKAIGV"
     gene            complement(29860..32979)
                     /locus_tag="PC512_001890"
     CDS             complement(29860..32979)
                     /locus_tag="PC512_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HDF2441632.1"
                     /translation="MDNIISVLNDVVFLDIEVSGLDCLNSEILEVGAVKVKDWKIYTY
                     ESLIKNKFEVPVEVFSVCKNLDKNDLEIANEIELVEDRLVNFVEDSFIICHDLSLKKK
                     FLEYHMPKLKNKFIDLIELAVILEPYHKDYSLEYLKNTLTNCNSKVENRALSDAIDII
                     NIVNCLLVKFNNYEKTTLEPLSFKINSYLKKFNLPTWEWSKFLEEANYDLSNNINIKK
                     EYNIFDSKEEKKKERETLKILNEEEKNYEELLKYKTIWENKEGFTYEYRPGQYELTKT
                     IRELFRNSEDEEKIACIEAPTGIGKSVGYLLPAILEARINKKRLLISTDTKELQIQLI
                     NKDIPNVLDSLGLNGKVSYGYIKGKNNYICIDRLEAYIDDYESQNPTKGEILSLIFLK
                     RLVEGGKYGDIEEINYLVFDNFKEISTHLRNVSCDPNMCRPKKCKKDCLYKNRIEELK
                     EEHITVVNHSLLAKWPYKDEKPLENIIVDEAHNLTEKGYDFFSSIINSKSLRYLLQEI
                     YPYEFIQNSSFIYKKYSRNMRKIKAFDKFYNVLKIGREDKQKIARSINLIIEEIDSIL
                     KFGNCNEYNNVSNYNLRWELNLQIDEIVGKLKKDGIDTEISYRAYSEKIKLSCEKIIK
                     NLVSIIIIIYRNIDDDSIDKEADIYKFGKAKTRDLEDIKIIFEIFLEYDEKDDYARIV
                     EIDKNYNDFEFRVVPLKIADLFEENILSQLEKGIFLSATLSLSESMSYFKNTLGIDRV
                     KNVEKIIEPIFDYKNRVSVVGFSDICEYRNSEFPNEMSKIISNISKITEGHTLALFNS
                     KDRQEKTYEILKKYLHSFNLEIYADKKGIRHLNDLNRKCVVLGSKGCFEGVDIPGDGL
                     VCVTLDKLPNLNPKDPLYFTIMKKYGIDYYTINYPQMTIKVKQAMGRILRSKYDYGCF
                     VIFDVGTNISVLKRLEKDLHDCKISKVNSNEFYTYIRRHLNKYRSLILKSVIFDTIKA
                     LNVDAKMDNNDVDKDIIKKDINENIRQRAVKGEVYHIDIIKKDMKVKYFDRNYLINLD
                     IFMREEDKN"
     gene            33200..34024
                     /gene="pdaA"
                     /locus_tag="PC512_001891"
     CDS             33200..34024
                     /gene="pdaA"
                     /locus_tag="PC512_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="delta-lactam-biosynthetic de-N-acetylase"
                     /protein_id="HDF2441633.1"
                     /translation="MKKDSLKKYIMIGAFALILFGIASINFKSLDKTKTQISSPTLDT
                     HEYDWYFNPREDGKQPSPIKEADFFKKYGAYYVGNPNEKVIYLSFDAGYESGNTPKLL
                     DTLKKHNAKAQFFVVESYIKSNPELIKRMEKEGHLVCNHSKSHPSMAGITDFEKFKEE
                     ITSVEKAYKDVTGKEMPKYFRPPMGKFSEQSLKYTQDLGYKSIFWSFAYVDWYEKKQP
                     THEFAKNKIYSRTHPGAIVLLHPNSSTNTEILDEVLTHWEKEGYKLKTLDYLNNKK"
     gene            complement(34121..34906)
                     /locus_tag="PC512_001892"
     CDS             complement(34121..34906)
                     /locus_tag="PC512_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2441634.1"
                     /translation="MIVKIDNTLEKEFWQYVSHEESLNLFIIGYVENYGFSSQYQDIW
                     SQVEDGNITSIILKNKSTLIIYSFKNNFNIGEMKNHIKDLDVESISGKKCVIDRLISK
                     YKDFYEKLDNKFCVLKEIKEIDFSNMKEYKIENAQEKDIDEIGKLLNRSDYKVSKNYI
                     EERKVHLKEGNVRAYFIRNDDTMISTVSTGMETSFLAMVVSVSTDKRYRGKGLASYMV
                     YNLSKELLLEGKVPCLFYNNDVAGKIYHNIGYKEINEWTILFK"
     gene            35371..35736
                     /locus_tag="PC512_001893"
     CDS             35371..35736
                     /locus_tag="PC512_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2441635.1"
                     /translation="MKIRAEYTCLLEIVHDIIKGKWKTILIFELRQSNKTFSELQHNI
                     YGINQKMLIQQLKELRDFGIIDKISSAGYPLHVEYFLTNRGKKMLKAVEIMQEIGIEY
                     MLEHGQQEILDNKGICYNK"
     gene            35814..36368
                     /locus_tag="PC512_001894"
     CDS             35814..36368
                     /locus_tag="PC512_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HDF2441636.1"
                     /translation="MSIALILIDIQNDYFKNGKCELFQSEETAENAKKILLFFRKNNL
                     PVIHIQHISTDKTASFFLPNTHGSEINKIVFPLDNEEIITKHTPDSFFETDLQSILEK
                     KNITNLVICGMMSHMCIDTSVRTAKKLRYDITLISDACTTKNLSWNNIEINANTVHQV
                     FMASLQNSFADVKNTDKFLSNYHK"
     gene            36588..37262
                     /locus_tag="PC512_001895"
     CDS             36588..37262
                     /locus_tag="PC512_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HDF2441637.1"
                     /translation="MNHHILIQFEYIARIITAGFCGALIGYERKNRLKEAGIRTHFIV
                     ALASALIIIVSKYGFNDIVGTPGIGLDPARVAAQVVSGIGFLGAGLIFIRNQSVSGLT
                     TAAGIWATAGTGLAIGSGLYLVGIVSSIIIVIVQITLHRDRKWMKLPTAEQVSLKISN
                     STDSIEYIEGKFKKSNIEIINMNIKRLDGDWLEVVIYTKLPKGYKKTNLLKLFSDNPL
                     IETLEI"
     regulatory      37617..37713
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            37767..37943
                     /locus_tag="PC512_001896"
     CDS             37767..37943
                     /locus_tag="PC512_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441638.1"
                     /translation="MFRDEMDKCTHMLTAYISSLYDYCDFIDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     gene            complement(38131..38370)
                     /locus_tag="PC512_001897"
     CDS             complement(38131..38370)
                     /locus_tag="PC512_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441639.1"
                     /translation="MKCSNCGSVNIEKGILTTGGIYAETIGLKYRGDGKLDKVINKTF
                     PVQSTIYSDLCLDCGEIVRTYIKDNTDRNWCKDKK"
     gene            complement(38504..39313)
                     /locus_tag="PC512_001898"
     CDS             complement(38504..39313)
                     /locus_tag="PC512_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2441640.1"
                     /translation="MKDYYKIGEISKIYGIGRDSLMYYEEIGILRPVRDINGYRMYNI
                     SDIWKLNLIKEFRSLNFPMKKIKEYLDDRSIESTKNILNEELDLIDKKIAEFISHKEN
                     IIKRLSSIESVIQNTKIDEIEVVYIEKRKALELNADIKRDEDFDFLIQKLQKEYEDRF
                     NILGNNNIGSAFSTEAINKGIFNEFKSVFCFLESNEKVYNIVFDEGYYVTLNYTGSNS
                     NNKIYMEKVFKFIEENNYKIIADPIEIYKIDIHETGIVEEFVTEIQVPITK"
BASE COUNT        12791 a         6634 c         4083 g        15890 t
ORIGIN      
        1 gttatactat gtatataaca atcgttttca tttataaagc ataatggagg ttttttatgg
       61 ttttaaattt agattttaat agtgataaat ctatttatgt acaaattaaa gaagaaataa
      121 ctaaggctat agcttcagga gaattgaaaa taaatgaatc acttccatct gtaagaagta
      181 tggctgaaaa tattggtgta aatttacata cagtgaacaa atcctacaat gaattaaaag
      241 aagagggatt cttaaatatt gatagaagaa aaggtgctat tgtagctcaa ctaccaatga
      301 aaatagataa tacaactcgt caaaaaaata aacttgactt ggaattattg gtggcaaaat
      361 cttatttatc aggtattagt aaagaagaat ttttgtcact aagttcaagt ttatttgaca
      421 agtatgaggt gaaatattat gagtaagatt gaatgtctat ttacaatatt tccagttcta
      481 attttgatgt atgctacatt ttattttatg ccctattttg taggtaaaaa acacatctat
      541 ggagtttcta tagaccaaga gcataaaaat tataattact ttataaagtt agataaagaa
      601 tttaaaaaac tattatcttt aggttttatt atagacttta tattagtttt tattctggtc
      661 tttacattta ataaattgga actttcctat tttattggta ttataggttt tttattatat
      721 gaaagtatac tatatattca tacacataaa aaagctaaga agcttaaatc agaaatttat
      781 tctaaattag gtcatataga tatagattca aaattaatag tagatatgga ttttataaat
      841 aagaaaaata aaataataaa aaaatttaaa ataatctatt taataccgat actatttact
      901 ttgggaatga gtatttttat agcatttaat tataatcaat tgccagactc aattgccact
      961 cattggaaca taaatgggtc tcctgatgtt tttatagata aatcatttct taatgtattt
     1021 aaattaatcg gtactgactt ttgtttaatg gttttattat atataacttc cattggatcc
     1081 ataaagtcaa ggattaagat agatacaaat agaattgaag aaagtagagt tgaaaacatt
     1141 aaatatttaa ataaaattgg ttatttgttt ttaatattga tgattataat gacaacacag
     1201 ttttttacta ctcttttatc aataaaaaca aaactatcaa ctgctatgaa tattacaacg
     1261 cttttagtta taatttattt aatagcaaca tatattaatt ccccaaattt aaaattcaac
     1321 tcatcttatt ctccagaaga agatgagaag tattggatag caggcatcat gtataataat
     1381 ccaaatgacc catcattaat ggttaataaa aggtttggta ttggatggac tataaatttt
     1441 ggcaatcctc ttggaaaaat actatatatt gctatagctt tacttttaat tttttcattg
     1501 tttagcctaa taaaatctct cttactttaa aataccataa aaggtatctt acttgtatta
     1561 ttgggtatta tattttgtag gataagaaat atttcatatt atcgttgaag tatagtattt
     1621 atatattact aagaatggag attttcataa tgttgtcaaa agctgaaatc aaatatttta
     1681 atgaatgtgc ttctgagata ctttcttctg aaaaagttca acttatgaga acatttcctc
     1741 atcatggcaa tgtttcatgt cttgaacata gtttgtcagt agcatattat agttatctat
     1801 tatgtaaaaa attgcactta agtgttgata ttcaaagtgt tattagagga gctttactac
     1861 acgacttttt tctttatgat tggcattaca aaggtgatag aaaaggatta catggattta
     1921 ctcaccctag agaagcatta aaaaatgcaa ctttattttt tcaaataaat gaaaaagaaa
     1981 cggacataat tttaaaacac atgtggccac ttactgttaa gccacctaga tacaaagaag
     2041 catttattgt atgtttgttg gataaatttt gctgtttagt tgagacttta aagatacatt
     2101 ctttattatc tccttaccat gtataggaca attcccacaa cacttttata acttaatttt
     2161 gaagaggtat taagtattat attcaacttg atacctcttt actatttatt attttatata
     2221 ataatatttt ctttataata tagttataaa taacaacttc taccctcgat aacttcccct
     2281 tcttatagac atgcttacta tcttaaataa caagaaacca gctattaaat ttattagtat
     2341 tgtttatact actctaacaa taatatcata aataaacctc caaatagctt ctctttcact
     2401 accttttatc ttaaactata tttttttctt aaaatttgta aaaaacatag cataatcttt
     2461 ataaatgttc taaaatttaa tttaagcatc aaaattagaa aggatgatat tatgtttaaa
     2521 gaaatgagat tgaaaaaaag agaaatgaca aaagaagata ctgttgaagt attaaaaaat
     2581 ggtgaatttg gtactttttc cactatatct gaaaatggtt atccttatgg agttgctgta
     2641 aattatgtat actttaatga ttctatttac tttcattgtg caagaaatgg gcataagtta
     2701 gataatatat cgaaaaacaa caaagtttct tttttagtag ttgctaatga aagtgttatt
     2761 ccagataaat ttagtactac ttattctagt gctatagttt ttggaaaagc ttgcactgta
     2821 gaaaatgaag aaaagaaaaa tgctcttgta gaaataataa aaaaatattc taaaggattc
     2881 tttgaagaag gcatgaagta catagagaag gatatgaact taacaactgt tgttaaaata
     2941 gaaattgacc atatttctgg taaagcttca cgtttataat taagtaaaaa tacctaaaag
     3001 tatatacagt cgcttttagg tatttttata tgatattctt atatgttaag tctttttagg
     3061 taatctctta tacctatctt ggcatcatca tttggtctta tatcagaatt atctcctgct
     3121 atatgaagta ttccatacgc tggataacct cctcttactg aacatggaac tgacaaaaga
     3181 gtcattccca tatgttgggc aaatatattc atagcttgca aagctaattc tcctcctcca
     3241 tgttgtgaac ctgctgtagc aaaacaacca aatattttac cactcaaagg agtacctacc
     3301 caaatatcag aaaaactatc cataaacatc ttcattggtc cagatacatt tccataatat
     3361 gttggtgaac ccataaatat agcatcataa tctaatattt cttttccaga tttaattaca
     3421 tttatacttt caaattcgtc tttgtattct ttggaattta tcaaataata ttgaggaagt
     3481 gtttttgcaa cttcgtcact tactctaaat atatctacct cgatattcat ttcttcaagc
     3541 gcttctttat attctctagc taataaatat gtactcccac aaacactatg aaaaattact
     3601 gctactttca tcattatccc cctaattaaa ctcaaattta ttttttatat agtattttta
     3661 ttatcaaaca ctgctaaata gtactaaatg gattcaaata tacattactt tttattactt
     3721 caatttcact aaattcatct aaaaatctct tcataacatt tttgaatata tcttctgtat
     3781 caaaatgacc acaatccact atacacattc caatatcaag tgcatcttgt gcctcatgat
     3841 actttacatc acccgtaatt agtacttctg caccttgtct cttagctttt tttacaaatt
     3901 ctgaaccagc tcctgttaca acggctactt tcgttatgtc tgtactaagg tttccaacta
     3961 ctcttatgtg tttcatattt aatttctctt ttattttcct tgaaagactt tctaatgtca
     4021 tacttttatc aagtttactt attctaccta gtccaaatat ctcaccttta ttttctaact
     4081 tgtacaaatc atatgcaact tcttcataag gatgtgcatc taacatagaa cttattaccc
     4141 cacctaaaag cttctgtggt actacagttt caattttaac ttcatttaca gtttctatat
     4201 catttacact tccaagaaac ggattagagc cttctaatgg cttaaattgt ccttcacctt
     4261 ctattgaaaa cgtacaatca ctataattcc ctatatgacc tgctcctgaa ttacttaaaa
     4321 cctttctaag ttcatctgaa tagttatgtg gaacgtatac tgctaattta tacaaatttt
     4381 cgcttttagt tatatctaaa acctttgaat taccaaattc cataatttcc ataaaatagt
     4441 catttagacc atcaaatgct atatcaaaat tcgtatgcat agaataaagt gatatatcat
     4501 ttttaataag tttttggata agtctgcctt ttaaatctcc actattaatt ttattaattt
     4561 tcccaaatat aaaaggatga tgtgtcacaa ttaaatctat atttttggat atagcttcat
     4621 caataacatc ttcattagct tctaaagata ccaatacctt ttttacatcc atatcaaaat
     4681 ctccaactat aagacctaca ttatcccaat cctctgctaa gtttagagga tacttttttt
     4741 caatttttct agttagactc tttaatagca tatatacctc ctatttattt tattaaattt
     4801 tcaagttttt ttattgcaac ttcgctttcc tttctcttct tatctatagc ttccccattt
     4861 ttcccttcta atttattaac tatagaacta tatgtcttta tctttttttc tataaaatca
     4921 ttaaaaagag aatctttgtt ttctaaaagc tttattccaa cctcataata tatctcatct
     4981 tctattatag tatttttacc tgtatatttg gcaacaatta tctcatatat tctaaaatct
     5041 tctctcacta aaacttcttc taaaatttca tatccgttgt ttaaaaggta atatctaagt
     5101 tcttcttgtg cttgcattgg ctgtaatatt aatttttcta cattatgtgc tacttctttt
     5161 ttagcctcga gaagctcact tatcaagatt ccacccatac cagcaattat cacttcttct
     5221 acttccccta tttcaagtat ctctatacca gaacccaatc gtaaatcaac tttatctaaa
     5281 agattgttct gtatgacttc tttatgtgca ttgtcaagag gtcctttatt aacatccgct
     5341 agcactgcaa atggtacttt tccctctttt aacaaatata ctggtatgta tccgtggtcc
     5401 gtccctatat cagctatttt tttaccatct gacactaatg atgctatttt caataatcta
     5461 tctgttaatt tcaaatataa ttctcctttc aattcccttt atttatagga tttaatccaa
     5521 gttatagata ttagactgaa ataactacaa aaataaaatt aaatctttac tacaaaatag
     5581 ccatgagata tcacttatct catggcattt atcacaaaaa catcaatgat gtatcttttt
     5641 agtctaaata atctctaagt ttttttgatc tacttggatg tcttagtttt cttagtgctt
     5701 ttgcttctat ctgtcttatt ctctctctag ttacatcaaa ctcttttcca acttcctcaa
     5761 gagttctggc tctaccatcc tcaagaccaa atctaagctt taatactttt tgttctctat
     5821 catttaatga accaagtaca tcttctattt gttcttttaa taaagaatat gctgctgcct
     5881 ctgctggggc tggagcatca tcatctggaa taaagtcacc taaatggcta tcttcttctt
     5941 ctcctattgg tgtttctaaa gacacagggt cttgagctat tttcattatt tctcttactt
     6001 tatcttctgt catttccatt tcttttgcaa tttcttctgg ttttggatct cttccaagtt
     6061 cttgaagtag ttgtcttgat actcttatta gcttatttat agtctctacc atatgaactg
     6121 gtattcttat agttctagct tggtctgcaa tagcacgtgt tatagcttgt cttatccacc
     6181 atgttgcata agtactaaac ttatatcctt ttgtatagtc aaatttttcg actgctttta
     6241 taagacctaa atttccctct tgtattaaat ccaagaaaag catacctctt cctacatatc
     6301 tttttgctat acttacaact agtcttaagt ttgcttcaac taacctttgt tttgctatct
     6361 catcaccttc gtgcatcctt ctagcaaatt ctacttcttc atgtggttta agtagaggaa
     6421 tttttcctat ttcttttaag tacattctta cagggtcatc tatacttatc ccttttggta
     6481 aagataaatc cacagtttct atttctattg cagaagagtc atcatgtgaa attgcctctg
     6541 catcttcatc taagtggcct atacttaaat cgtcatcagc aaccgaaaaa tctatatcag
     6601 ctttatagtt ttttgtttct gttatttcta ttcccaaatt tcctaaagtc tcataaagat
     6661 tttctacttg atccttatca agttcagtct ccgaaaaagc ttccattatc tctgcaagtg
     6721 tcagagaacc ttgctttttt cctttttcta ttaatgtctt agcagtaacc ttttttaact
     6781 cttttttatt cgatttattt tccacactca aacctccttt ctctacaagc tctttaaaat
     6841 tttatttatc tcaactattt ttaaagcaat ttccataact ctaccatcta cctctttcat
     6901 atcattatta ttttctaatt cttgttgttc tctcaacaag ctattaattt gctcttctaa
     6961 tgagtttttt ctgatatttg ttattattcc ttctatttct tttgtgttct ctaagtttat
     7021 actattcaaa gaaattgaat ttaattcttt taagtattct tcggatatgt ttaaactttt
     7081 caatttgtca atagttattt tgtccaattc ttgattttta atcatgtaat ttaaaatttc
     7141 tttactttct ttcaataaaa aatcactttc ttctacttta agtaacgcta tttctctaat
     7201 ttttttgtct tctaacatta tttttattag agtttcttca actaattgtt ttccgtcttg
     7261 tctgacttcg actttttcaa ttactttttc ttctattttc ttttgatttt tgttattata
     7321 tggcttattg taatttttac cataaacttc tctctttata gactcgacat taatatctat
     7381 ttgattgctt aaatactttg tataaaaatc aatttcaaca ggacttgtca attgttttat
     7441 aattttagaa gcttcttttg cgaacttcac tcgttcttca tctttttgaa tgttaaattc
     7501 ttttttaaga tgatctattt tatattttat gtagtgagta gaaacatcca tagctttttt
     7561 ataatcacta agtccgtatt ttcttacaaa ttcatctggg tctttagcat cttttaagtc
     7621 taacactttt acattgatac ctaatttagt aagtatatct atagctctta aagtcgcttt
     7681 tattcctgct tcatcagaat cataagatat aatagcagtg tccgcatatc tctttattaa
     7741 aatgccttgt tgttcagtca aggctgttcc aagggttgct actacatttt ttataccata
     7801 ctgataaagc gaaattaaat ccatatatcc ttcaactaag actatagttt tactttctaa
     7861 attttttcta gcaaaattta atccgtataa gttctgtttt ttattaaaaa ttaacgtgtc
     7921 tggagaattt aagtattttg gcaaagaatc gtctaatact cttcccccaa atcctattat
     7981 atttcctcta taatcgaata taggaaacat aactctattt ctaaatttat catagcaatt
     8041 agttccatct ctattttttg caattagacc gcactccaat aagtcttgtt ttttatatcc
     8101 tttactgatt agagtattca taagtgaatt ccatgaatcc aaagaaaatc ctaaaccaaa
     8161 tttcttaata attttatcat ctagtcctct tattcttaaa tattcatacc caagattttt
     8221 gcttcccaat aagtttgaaa gataaaatct agctgcttcc gtatgaatat cttgaaattt
     8281 cttagatttt tctattttaa tcctagtttc ttcattcatg ttagtgttaa tttctatacc
     8341 gcatttattt gctaaaattt ttacagcatc cataaaatcc aaattttcca ttttcatgac
     8401 aaaatttatt acgtctccac cttcaccaca accaaaacac ttataaatct gttttgacgt
     8461 atttatataa aaagaaggtg tcttttcgcc atgaaatgga cataatcctt tgtaattagc
     8521 tccagattgt tttatattca tatattcaga tattatactt gctatatcgc atctagcttt
     8581 tatttcttca ataatgtctt ttatatcatt catattatca ccttctggtg taattttttg
     8641 tgttaacatt tctattctac actatattct aaatttgtca atcactcaat atacacaatt
     8701 cgactttttt tattgatatc cttcttatta atcaaaaaat ttttattttt tatattaatt
     8761 ctatcaatat taaatcttta tttatattaa ataatctaac tatcaaatta taacttataa
     8821 atttacctta gcaacgatta cgaataaaaa agaggctctt gcctctttta ataattatta
     8881 attgatttca ttaaatcttc aaattcatta aagcaaagag attgagcacc atctgacaaa
     8941 gcattttctg ggtcaggatg tacttctacc attattccat ctgctccaca tgcaaaagat
     9001 gccagtgaca taggttttac caaatatcta actccagtgg catggcttgg gtctaccaca
     9061 acaggaagac ctgtttcctt ttgaataatg ggtactgcag ctaaatctaa tgtatttcta
     9121 gtataatcat tatacgttct tatacctctc tcacacatta taatattact atttccttct
     9181 attgctatat attcagaagc acctatccat tcagtaattg tggaagctat tcctcttttt
     9241 aacataacag gtttattttg ttttcccact tcacttaaaa gagtaaagtt ttgcatattt
     9301 cttgacccaa tttgaattat atcacttata ctatacagtt cgtccatatc tcttacatcc
     9361 ataagttctg taataacagc cataccaact tcgtctttaa ccgcttttaa tatttcaaga
     9421 ccttcttttt ttaatccttg aaatgaattt ggagatgttc ttggcttgta tgctccacct
     9481 cttaaaatat ttgctccctg actttttaca aatttagcag tctccaaaag ttgctcataa
     9541 ctctctattg cacatggtcc agctattata agtttatctt tttttacagt tatctttttg
     9601 ttatttgtat ttatctctat ctttgaatta ttattaaata ggttttcttt cataacctac
     9661 aagctccttt acttcttctc tttcttcagc agataggagg tttaaatgtt cttttattgt
     9721 tttttcattt attataagtt cttcatttaa atccataagt ggtatcaaaa cgaaagctct
     9781 atcttgaatc cttggatgag gtattgttag tctttcatca gtggaaacta catcattaaa
     9841 aaatagtacg tctacatcta tagttcttgg tccccaatga actattctct ctctgtgtag
     9901 ttctctctct atttcttgac aatattctaa caactcataa ggttcaaact ctgtttctat
     9961 ttctacacac atatttagaa aatctgcttg ttctgtatat ccccatggtt ttgtttcgta
    10021 taagcttgat tcttttactt tatatataga atcactattt ttcaaaagtt cacatgctct
    10081 tgataaatta tcaaatctat cacccatgtt agtacctatt cccaaataag ccttattcat
    10141 ctcttgttct ccttatctca acaccaaaat agtcataaat accatttaca ggagcctcag
    10201 gctttctaac tctgaccata actccattta taagtataaa tttattcaag acttcttcag
    10261 caatattttc cgctaaagcc tccaaaagat taaattgttt attttcagta atatctttaa
    10321 caacattgta aacctcggca tagcttacag atttatttat atcgtcacta agacctgctt
    10381 ctcttgaatc aatataaagt tccatgtcga caaagaattt ctgacctaga aaattttctt
    10441 ctttaagaac accatgatat ccatagaatc ctagattact aagtaatatt ttatccatta
    10501 tattatacct actttctata tattgcatca gtcattctag ctgccattaa attttcataa
    10561 acatcatgta ctctaactat atctacgcca tctcttatac caagaacagt agtagctatt
    10621 gtaccttcta atcttttttt aggctcaact ggaagtactt ttcctattac tgattttctg
    10681 gatgtcccaa gcaaaatagg ataccctaaa tcttttaatt catttaatct tctcaatact
    10741 tcaatatttt gttcaaaatc cttgccaaat cctacacctg ggtcaagtac tattttttct
    10801 ttttttacac cacaactcat tgccatttct atacttacct taaaaaagtc ttttattgac
    10861 tccattatat ctttgtcata gtttgtccca tcttgattat gcattataca cacttctgca
    10921 tcatattttc ctattacaga agccatattt ttatcttttc taagacccca aacatcattt
    10981 accatagtga cacctaattt taatgcttct tctgcaacat ctgccttata agtgtctatt
    11041 gatattggta tatccaattc ctgtttaagt ttttttatta cagggattac tcttcttagc
    11101 tcttcgtctg agtctacata gctatgacct gggcgtgtag actctcctcc taggtctatt
    11161 atatctgcac cttggtcaac catatctttt gcatgttgta ttgctatgtc caagttatta
    11221 aaatctcctc catcagaaaa actatctgga gttacattta atattcccat tatataagtt
    11281 cttttaccat aatcaaacac aattaatgac actcccttaa attaaatttt atctcaataa
    11341 atgattatat ctataataaa ttactacttc atagtaatca aactcatagc ctcggctcta
    11401 gacgcaatgt ccttttcaaa tattcctctc actgctgatg taacagtttt tgaacctggt
    11461 ttttttacgc ctctcattgt catgcacata tgttcagctt ctactactac taagacacca
    11521 taaggttgta attcttccat tattatatct gcagcatttt tagtgattct ttcttgtaat
    11581 tgtggtcttt ttgccaatgt atctattact ctagcaagtt tagaaagccc tgtaagtctt
    11641 cctccttttg gtaaataagc aatatgagct tttccaaaga aaggaactag atgatgctca
    11701 caacatgaat aaaatggaat atcttttacc aatactaact cttcatgttt ttcatctgca
    11761 aaaagaactt ttaaatggtc tcttggttct tcactaagac cagagaatat ctcttcatac
    11821 atcctagcaa ctctatttgg agtttcgatt agaccttctc tatctgggtc ttccccaatt
    11881 gcctctagta tttctcttac tgcatgttgt atcttttctt tatcaacttt attcatttaa
    11941 actcccccca ttgatttgtg actagaagat tagttttata acctcttttg tctcaatttc
    12001 tttaaaaata taattataaa catctaaaag tctttgatag tcataatttt cacttacttt
    12061 tgacactagt tcaaaaagct cattattttc tttttttaaa acttttagca attttttgtc
    12121 ttttggtacc catttatcat ttatattaaa gtacccaatt attatatctt ttaaatataa
    12181 attcgtcaaa aaatgatatt caaaaacatc aaatttttct ttatttttta aattcaatat
    12241 ttttgctcca atatcttgct ttataaaaga cttttcctct aatgacattt tactaggtcc
    12301 ttctaagtaa atatctctac ttatatcttt tataatatgt gatatattct ccctatcaaa
    12361 cagtacttta gcatctttca tttctttcac aaagaaatat tccctatttg ataataattt
    12421 ttttacacca tcttttgaaa agtaatttac atcaaattct attccctttt ttttaaacag
    12481 tattctctct tgtttttccc cttcttttac aaaaacgaac acatcaatat cgtttatcac
    12541 tacatcataa agagtaaaat ctacatcttt actagaaccc actaaatata cagccaaagt
    12601 gttttggttt tctattattt tagtcatctc ttcattgtat acttcataaa tacaacctat
    12661 catcttttgt ctccaacaaa ttgttaatat tttaatttat tctaataact tcactatttt
    12721 atcaaaaaca acattttctt tattaaattt tattttgtca atttctgtaa cctttatagc
    12781 gcccataaga ctatttgtga caaaaacaaa atcaaaacta ctaatttctg atatattaat
    12841 ttcattttct atcaactcta tatgtaattc gtcacaaatc tctataatcc ttttttttat
    12901 tattccattt aatatcggta atctatcact aggagtgtac actctttctc cttttataaa
    12961 gaaaatattg ctcatagaac attctaatat tacaccttct gaatttaaaa atataccatc
    13021 attataacca gtcttatttg cgatattttt ggtatatatg ttttcaaaat aattagtagt
    13081 cttatgtcta tgaattaaac tattccccct aactattgga gatatagcta atttaaaccc
    13141 cttctcatac gtctcttgat tatatggaat atccctaata gatatattat aaccttcatc
    13201 aaaaacagta attctaagtg ctttattaat gacattttct ttttttatat atgtaacaat
    13261 ttcatttatc aagaaatctt ttttatagtt tatatctaaa tccaaacaat ttattgagct
    13321 tagcattctt tctatatgga tatctaaatc tactgctatt ccatttttaa ctctaatagt
    13381 ttcaaacaaa ccaattccaa atttacttaa actactatca aaacctacat tattcttcat
    13441 aatatcccct caaagccttc attatggatt tagctttatc aagtgtttct tgatattctt
    13501 catctgggtc agaatcccaa gtcattcctc ctccaacttg aaagtagact tttttgtcat
    13561 ttttgattat tgttctaatt gctatattaa aatccatatc accattaaaa cctatataac
    13621 ctattgaacc agtatataca tttctttgcg ttggctctaa ttcgtctata atttccattg
    13681 ctctaatctt aggtgctcct gttatagacc cccctggaaa agttgctttt attacatcag
    13741 tagcatcttt atcatctttt aactcaccta caactgtgga aactaagtga tttacatttg
    13801 catatggttc aattacaaat agctctggaa ctttaacact tccagtttta gatattctcc
    13861 caatatcatt tctttctaaa tctactatca taagtagttc agctctatct ttttcactat
    13921 ttctaagttc ttgttgaagt cttaaatctt cttctttatc tttccctctt ggacgagtac
    13981 cttttattgg tctagtttct attctcttat taacacatct tataaatctt tctggagaat
    14041 ttgataatat atgtgcatct tcaaagttta agaatgcccc aaatggtgct gggctaaatc
    14101 ttcttaagtc cctatacaat tcaaagcttg taagttctgt ttctccactg aacctttgtg
    14161 ttaaattagc ttgatatata tctccttgtc ttatgtactc tctaacactt tgaactgcat
    14221 ttttaaattc ttcctttgta aaattagatt taagtcttat aggtgttact tctttttctt
    14281 cataacatat gctatctata ccttttttct cttcttttaa tattctttgt tctatatcat
    14341 ctattatctt ttcttctaat tcgatatcta tgtttggagt agctatataa gttttttgca
    14401 caagatggtc tataactatt acatgattat aaaatccaaa atacatatca ggcatctcaa
    14461 tatcatctac agcagttcta ggtaaatttt ctatgtaatt acctaaatca taagataaat
    14521 atcccacagc acctcctaca aatggaagat tagtatcatt tacaacccta tacttatgta
    14581 gttcttcttt taaaacttct aaaggatttt catcagtatc tttatacttt aataccttaa
    14641 atggttggct acttataaaa gaatatcttc ccaatttttc tttatccata gcactatcta
    14701 atataaaact gtcatgttca tttctaaaaa tagtaaatat ctcaaaagaa tttaatttag
    14761 tatttatctc tcttatcata ttacatatgt accctttctc tagcttctgt tataaaattt
    14821 ttaagcattt catgaccata ctctgacaaa atagcttctg gatgaaactg tactccttct
    14881 attaaatatt tcttatgcct aattcccatt atttcccctt tatcagtaat tgctgtaatt
    14941 tctaattctt ttggaactgt attggagtca actattagtg aatgatacct agtgacattt
    15001 aaaggatttt taagtcccct aaaaactcct ttattagtat ggttgatact atatactttt
    15061 ccatgcacag gctgttgtgc ttttataata tctcctccaa aaacatgtcc aatagtttgg
    15121 tgacctaaac aaattcctag tataggtttt ttccccttaa aatgctcaac aatatctatg
    15181 caaataccag cttcttttgg agaacacggt cctggagata acacaattac ctctggattt
    15241 agttcttcaa tgtcacttat tttgatttca ttatttcttt ttactacaac tgcttcccct
    15301 aattcttcta tatattggac taggttgtat acaaaagaat cataattgtc tatcataaga
    15361 atcatactgt aaatctcccc cctaaaaatt attttatcaa ctcagaaact gttacaaatt
    15421 taaaaccttt ttcaatcatt tttggaataa acatatctaa agcttcaact gtatcattag
    15481 ttgcataatc atgcaaaagt attatatctc cattttgtac tttattaatt attttatctg
    15541 caatgctatt agctcctgga tttttccaat ctttcacatc tacacctgtc cataaaacaa
    15601 ctttatagtc atgctttttt gcaatttcta ttaagtcttt ttctctataa cttccgaatg
    15661 gtggtctaaa taatgtaggt tttttcccag ttacttcctt caaaatgtct tcacacttaa
    15721 caatctcctc ttctatctga ctagaactta aattacttat atcaggatga ttgaaagtat
    15781 gatttcctat ctcgtgacct tctttacttg ctcttactaa tggttcttta taccattttg
    15841 catgttttcc agctataaaa aaagtagctt ttacattgta tttctttaat acatctaaaa
    15901 cttgactagt ttctttagga tgaggaccat catcaaaggt aattgctatt agcttttttt
    15961 cccttgaacc atgtttaatc aaaacatttc cattagtatc catcatcaaa gcagaaactt
    16021 tactaaaatt agatattaac actattccac aaaacaaggc tactgctatt aagcacttat
    16081 atactgtctt ttttttccat gatgtcattt tttaacttcc tttcaaatat tttagttatt
    16141 tataaaaatt ttgagtgtaa tatgttttat agcttcctcc aaatattact ccaactccaa
    16201 tattattata gttccccaaa atattttttc tatgtccttc agagttcatc caagcttcat
    16261 gcgcatatat tgcattaatc tgtcctgctg ctatgttttc tccagctgaa gtatatacta
    16321 taccttctct tttcattctg tcaaatggag tttcattctt cttatttaca tggtcaaaaa
    16381 aattattatc tctcatatct tcactatgtt ttcttgaact caaagttgcc tgttcactgt
    16441 atctcaatga gtttaaccct ctttgatttc taacactatt tacaaggtct ataacttcaa
    16501 gttcaaaaca ttttttaagt tcttcgctat catctggata taaattttta aactcatctt
    16561 cagtgctttt atcaattatt aaatatgaac aaactctatt ttcttcatga atatcgtaga
    16621 aaattgtaat atacttacct tccttactta ttatatcata ttgattttct gagtttatta
    16681 tatatctggt atttcctttt ctcttatatt ttaatggtgt aatcttagtt ctcactgttt
    16741 gtctatcttg atttagtttt atatcttgat tttcacatga attaatagaa ttactataaa
    16801 gtgctactac ttcatcattt tcaagtccaa ccattgcaaa ttcttttcca tattgattat
    16861 atacatacca atcaaaacca tattcactaa tatcaattct accaggtttg ccgatacttg
    16921 ataaaacata gcttaaatta tctcctaagc ttattttttc aaaattcttt atatctgact
    16981 ctcctaagtt ctccccttca gtattatttg attgtaaatt ttgacttttt tcttttttat
    17041 ctttcttaga attatcattt atatttattt tgtctaaaaa ttcattccat atttcacttt
    17101 gaaaaaactt ttcttttaaa tcatatcctt cttttaataa ttcaggacta taaaataaaa
    17161 caataagtac tactaacact aaagcaatta atctcttcaa tatatctctc cttcttaaaa
    17221 tcaatcaaaa ttttttaata ttgcatttat taagttaata ttgatagtgt atactaatca
    17281 atatcattca tacctattta cagtaagtat tagaaaaaag ctttatctac taattagata
    17341 aagctacagt ctcaaggaaa atatttcatc taatgttcta tcaaatatag atggcttatc
    17401 aaatttccaa gtcccttcat aaaccaattc attatttaga taaaaagttc cttgcccatg
    17461 ttttttacca tgcataaatt cacctatata ctttttacct ttttcccata tataagttcc
    17521 cttaccatga atcaaattat tcttccattc tccttcataa agtacttccc ctttactatt
    17581 atagcaaata ccgtaccctt ccatctttcc acctttaaat tcacctgcat atatacatcc
    17641 atcactccac ttataaatac cttttccatc tttttttccg tttttccaag ttccaatata
    17701 ttcatcttta ctactatata acatatttcc aataccgctc atcatatctt cctcaaaata
    17761 acctatatat tcatttccat ttgaaaatat aaagtttcct tttccatttt ttttatcttc
    17821 tttaaattct cctatgtact ccataactgt tccttcatct acaaaaaaag tatatgagcc
    17881 tttcccctcc atctttccct ctaagaattt ccctacatat acatccccat ttgaaaattt
    17941 atagatttta ttttttggtt tttttgtatc gacatcatct atatcgcgta ttgtttttcc
    18001 ttccaattct aatacttcat tttccggagc aaaatcgccc ctttttaaaa cacgtttctt
    18061 catgttcttt atacttctaa tctctttgtt tacttcattt atatatttca aataattatc
    18121 atacaaatta acatattctt tagataaatt cataatgcca ttcctccaac gttattccta
    18181 ggtattttac taaatctatt aaatttatta tatcctaata gtggtcatgt tttctacata
    18241 ttaagtaatt ttttcaattt taattttaaa atgatatctt ttaaagtgat acacaaatca
    18301 ttaataaaac ctttattttc gtatactaaa tttaaataag ctgagagata taatatacaa
    18361 atttacatta taaactccca gcttgtaaaa ttttctataa atcttttgct ttaaaccctc
    18421 ttccctttac ttctgtaaca tcatttacag atataaaggc ctttttatca tacttcaaag
    18481 ctatatcttt tatctttggt atctcatttg atgaaactat tgtatatata atcttctttt
    18541 tttgatgagt gtatgcacct tctgcatcta aaaaagttac acctctaact aaactcttca
    18601 ttatatcttc tgctattaaa tcgacttcat ttgacattac cataacagat ttttggtaat
    18661 tcattgcatc tttaataaaa ctcattgaat acgcatttag aaatagacct ataagagtgt
    18721 ataatgctaa atccaaccca aataaaaaac ttcctgtaag tactatcaag ccatttattg
    18781 ctaaagcagt gtctttcatt tctatattct tcttaatttt tagtattgca gctattatat
    18841 ctgtaccacc ttgagaagac ctagttctaa atacaactcc gactcctaaa ccagataata
    18901 taccaccata tacactttga agcaatatat catgtatagg tataatatta cttatttcct
    18961 gagttgctcc taataataat gaaaatacaa tcatatttac caaacttgaa atacaaaact
    19021 ctttttcaag gtatatgaac cctaagataa atattggaat attgattaaa aatgttaata
    19081 aacctacatt tatatttgtc aaatagttta tagatgttgc tatacctgta gcacctccac
    19141 taagcagatg tgctggtctt aagaacccat ttattcctat agatgtcatc aacatcccaa
    19201 atagcattgt tgaatatctt aaaactggat gtttttgtag ggtattctta acttcactca
    19261 tttctttctc ccttcaatct ttctaaatct ttagaatttt aaaagcttac tcttacatat
    19321 attattcctg atgtaataga taatatttca aataaatttt ttttataatt tcttgaactg
    19381 tcatctatta catcatctat tatattatct ttttcatata tgtctagtgc aatcttttat
    19441 attctaatct ttaaaaacgt tcaaatcatc tcatttatgc cttaaatgaa actttttcta
    19501 gcataatatg atactgctta ttatttaact tgcaatatag taaatttata gtattttttt
    19561 ctaaatatct attttagcag taatttattt tattttagca aattcaagtt tagtaattgt
    19621 ctctttataa ttaattccta aatgaaattt ttctttttat aatttcagta catgattttt
    19681 ttatttcatt atttgcattt ttttcgttca gtttttattt taaatttttt ttattttatt
    19741 ttgttttaag tattcaaggt actcatctta attttatttt ttatataaaa ttcattataa
    19801 ttggaattag tattactgta attgtaccag agactccaat agaaacacca ctcatagctc
    19861 cttctatttc tccaagttca aaagcctttg tagttcctaa agcatgtgca gatgttccaa
    19921 gagcaattcc tttagcaact ggatgattta tattccccag tttgaatact gtagaagcaa
    19981 ccataccacc aaaaatacct gtaaaaatta tggctacaac tgttattgat tctacaccat
    20041 ttaaagaatt tgctaaagat attcccattg gtgttgttat agattttgga attagtgaat
    20101 ttattatact tacatctgaa ttagctattt tgccaattat caatacagat acaaaagaaa
    20161 tcactatacc acaacctatt cctacaataa tctcaaacat atgcttttta aataattcaa
    20221 attgtttata aagtggaact gcaagtacta ctgtgacagg acctaaaaag aaatttagac
    20281 tatcagctcc tatcttgtaa ttctcataag ggattttaga tatgcttaaa aacaatatta
    20341 ttcctacgat tgcaattaat aaagggttac atataggatt acttgttttt cgttgaatgt
    20401 atcttcctaa attgaaaaaa actattgtta ctattatacc aaatactggt gtctgtaata
    20461 cattatacat ttttttgtcc ttcttccttc ttttttatca ttttctccac aataattcca
    20521 gtagtataca ttactattag tgtacttaaa catatgacta ataaaagcac taatacattt
    20581 tcccttatta ggtctaatga ctttataagt gatacacctg ctggaataaa aaatatagcc
    20641 atattatcga ggaaaaatcc acttacattt tctatactac tcaagtctaa aactttaaat
    20701 tgtagtagta gaaataataa tagcatacca actatactcc caggaataag tataattcct
    20761 tgtataaagg aacttatata ctctcctatt acccagatag ataaaattat taccaattga
    20821 ttgaaaactt tcattttcca cctccaaaaa ttaaagagat tgcttcaaat catatatttg
    20881 tagttttatc aacaagcaaa tatctttctt taaaatagaa agttataatt tgacacaatc
    20941 tctttttaaa tttattttta ttttaattta ataaaataca tacttggttg tttcaaaaaa
    21001 cttaactata taaacctatt tttcacttaa aatttctttt atttttgaat tgttatacat
    21061 actgtctgga acttcacttc tcaaactata aaaagtctgt tgtgcatttt ttaaatcgcc
    21121 attatcataa taaaacatac ccaactcgta atatgaatca tcataatact ggtcattttt
    21181 agtataagta tttatatatt ttttgtaata ttttatagct tcatccttat ttcctaataa
    21241 tttatttgtt attgctaatt gatatattga ctcagaaata tattttttag ttttaccaga
    21301 agaaactaca cttttaaaat tatctatggc tttttcatat tctttgtttt tctttaaatt
    21361 tagagcttga taatataaat cttcctcatc agctacagtt atctctcttt ctggttcttt
    21421 atttttaacc tcatttaatt ccttattcgt tttttctaat tttttactcg tttctcctaa
    21481 ctttttatca gtttcactta acttttcctc tttactactt atttggttat tcaagttttc
    21541 tattctcttt ttgctttgaa tcaaatatat ccccatacct attaaaacac agccaactat
    21601 aatatatggc aaaatacttt tctttctttt tacttttttt atttcttcct ttttacttgt
    21661 atcttctttt tcttcttcat ttttttcaaa tacaggatta tctttatcta gctctttaag
    21721 tttgtctaaa tatccttctc tcttttttac attacctagt ttatcatata acaaagataa
    21781 aattacatat ggctctatta gttcaggttc ttcttcaatt atgttctcta aaatatgtat
    21841 tgactcataa tttaattctt catttataaa tcttatagaa tgattgtatc ttcctaaaaa
    21901 agttttaaaa tcttcagatg aaattagatt tacatatttt ctagatatat gattattttc
    21961 ataacataaa gcagtataaa aactctcaaa tgatttagca aaatcacatt ttaataattt
    22021 taaaagacct ctaagattta gtatatcaat gtctttagga tttatctcca gagctttatt
    22081 aaccatatta atggcactag ttatataatt tttatatgct aaatccaatg cattgttata
    22141 tcttttatat gattctaatt ttaactcctt agacgttgta tctgactttg aatttaaagc
    22201 tccttgcaag tttaatagag tttcttcttt ataatttgta gtcacataac tctgttttaa
    22261 tgcttttaat gtttcatcac cgtcttcttc ttctatatta aaaaaagtca aatcactttt
    22321 attatcttct atcaaagata tatctaaaat ttttctaggc atgctttcta tgtcttgttt
    22381 tatatcttta actaaaataa tactcacctc cactctaaaa tatatattta agataacata
    22441 tttaatatgt caagtcaaaa ctatacatat ttttccacca ttctcataat aaaaaaggta
    22501 atcctcttct tttcataaaa aggttacctc tttttcaata ctattaactt ttaatgttga
    22561 atttttttac ttttctatag agtgtagcta tacctatatt taatgcctca gctacttttt
    22621 tcataccttc tgtattactt ccatatttct ttatggcatt ttctatagct tccctctcaa
    22681 ggtcatctat agtcttaact tcttgtttat aaagttcatc tagtttaaaa gatattaaat
    22741 cagacatact ccttacaaaa gcagttaact ccttatcttt tgaaagtatc ttttcttttt
    22801 gttcttcatt aaacgcagct atacccaaga ttccaagtat atgctctccc attttaacgg
    22861 gagtacatat atcagctaac tctttacaat tttctctatt tgcacattta ttacagttct
    22921 cttctatttc tttatttata acataggatt tcccatcttt taaaacaaga gagtacactg
    22981 acttctctga tattgtctct cctattttac ctctgaatat tcctgtacct gctatcctag
    23041 ttaaatcttt tgtaactaaa gtaacatcta catccaagac attagaaata ttctcgcaaa
    23101 tactttgaac gtaattcgtt atattattta aattcaaagt aatccctcct atttagattt
    23161 atatttttta ttactctaca taaatcctat tcttgagaac tttaagcttg cggttgtggt
    23221 tgtgtctcat taggcttatt atcagttggt ggtgtttctg gtttttgttg attatttggg
    23281 ttttgattgt ttgtattttg attattctta ttttcgtctg tatttggttt ttcctctggt
    23341 tttggttcca tagtcccaac taatataata ccttccttct taggataata tgaattagct
    23401 attttttcag ttttaatttt tttaccattt gcatcattaa atgttctata tgttgataca
    23461 gaatatgcat ttcttccact tttgtctact ttttctttac ctttaggcat tgtagggtca
    23521 ttaactcttt tcattgtagt ttgtgaaacg ccatctaatt ttgttgatat tgttatattt
    23581 tgtttatctt ctgcacttcc atatatattg caaacaattt gatttcctga aacgtaattt
    23641 tttatgtaaa ctggatgctt tagattattt ttaaataaga aatctattcc actatctgca
    23701 acagttgcat ctcttccttt tggaacataa cttgatggta tagtatgatt ttttacatta
    23761 acaatttcta aacctgcgta tagcacagaa ttgtataacg tagatgaaac ttgacaaact
    23821 cctccaccat aatcttcttc catctcacct tccattatta caggtgcact tttatatcca
    23881 ttttccttac ttcttttccc tgtatgttta ttaaatgaga aagtttctcc tggcataagt
    23941 aatacattac ttatattatc tgttgctaat tttatgttta tacttctatt tatttgagaa
    24001 gttttaaatg ttgttgaata cgtacctaaa tttgtatcta tattagcaag ttgctctttt
    24061 tttacttttg ctggagtagc ttttactact aactcatttt tatagttacc ttttttagtt
    24121 tgattatcaa aattctccat actcttagaa atatccattt taagaccatc agaatctggt
    24181 ataaccttga ctttttcacc acttatatca agtgtagcat cttttacatc tacatctatt
    24241 tctttagcta tcttttccat ttctgctttt aatttatttt tatcataatt tatcgcaact
    24301 actaagttgc tttttttgcc aaaatttgct gaaatagttt ttgatagatt gccaaagaaa
    24361 gcactctttc tatttaaatt atatgcgttt tctactgttt tatccaggtc agtagataaa
    24421 tttaaatctt tgctctttac tttccagctt ttatcattgt aattaaaatc aacattctct
    24481 aatttgtatt ttttagctaa ttcctgtttt gcttgtgatt tagttaattt tccaatattt
    24541 actccattaa catatgtgtt ttttgctatt ttctcccctt taaattgcat gcacattatg
    24601 cctataaaaa ttattactac taatgctaca gctccaatag ctataactag ctttttgttc
    24661 acattactca tcccatactt ctccttacaa taaaattatt tatatatccc tattattata
    24721 ttactacata atgcgcctta aaaccccaaa aactttttaa ttatatatta atttaatatt
    24781 attaattaat attcatttag tccattttct gatatggcat atattttttc attgtaaata
    24841 ttaatagcat aaacttcttt gcctctaaat aagcctttat ttactacagc ataataataa
    24901 atatttttat attttccaaa caattcttct aaactctttt tactttttac atatctatct
    24961 gctttctcta tatctaatat ctcaatcttt ttatacttat tttctttttc atcaagagta
    25021 ttagttaaca caaacttagc tttatctttt gtaataccaa attgataact tccatcttct
    25081 aatattctaa agtatccatc accataatct actttgtaat cttttttacc atctttatat
    25141 gaatataaat ctttagtttt tgcacttacc aaaacttcat ttattaattt atcatactca
    25201 tatacttcag cataatagta tttattattt tttatcattt gtggaagtga atttatagat
    25261 agatttgcct tgtctttgcc acttttttta gctattacat ttataatgtc atcagatgtt
    25321 aaagtataca atgataaatt ctttttatat tttttttcta aactctgtac cttttcatca
    25381 tctgaataat cgtcttttaa atactcaata tattgtaatg ctctttcata atctccagaa
    25441 gtatttgcct cttcagctct acttatatag taatcataca tttcttcaat acattgttct
    25501 ttcccatttt gagccatact gtaatacttt tcatcttctt ttaatacttt attatacttt
    25561 tcaatagctt cataatactt atatgctttt tggtctttta ctgctgagtc ataaacatct
    25621 ctagactctt tgattgtttc tatattctgt ttgtatacat ctaggttact acccatacca
    25681 tttaatattg aaacagtact tatgtagtta atggcaatat cataagtagt attttcttct
    25741 ttatacattt ctctaactct atcagcttga gctaataagt catccacatc tatacttatt
    25801 ttgtttaatt ctttcacggt atttattaat ccaataaaac tttcttgact tatgtctcca
    25861 tctaaatatt tatcaccact atttaatagc aatttattta tttttttaga aacagactta
    25921 ttaaaccttt ccatttttga atcagaaaac tttttttcta tacttgtgta gtaatcaaca
    25981 gctatagaat actgtctttt ctctataatc tttaacaact cattagcttc atttcctaca
    26041 ctaaactcgt tactacttaa gaaaaatact attatcaaag caattacacc taatgttgat
    26101 aatgaaatcg caactataga tttccttttt tcatcaataa aatctacagc cttctcaaat
    26161 aaatctctaa aattcattat agttccctct ccatttaata atctttatat tttatggtaa
    26221 actaaatttc ttattggtta ttatatcata attcttgaaa aaaaataaaa acacaagtta
    26281 aatcgtgttt ttattttacc tatcaatcat tattttatac ataaatattt cctttacata
    26341 aattatgata tctttctttt tatatcccta gaatgactct tttgtttttt attattactg
    26401 acagttttcg ttcttgtctt gtgtatagct ttgctatcaa atatttttct agcattgcat
    26461 aaaacaattc caattgttaa acaaactgta agcacacttc ccatcaaaaa gtaataatcc
    26521 aatcctatat gtactcccat aactgaattt attaacacta atgcaaaagt cattgcaaaa
    26581 catatcatca tggagataac taaaattctt agaatttttt tcaatccact cacctcgtat
    26641 aatcactaaa attgacacta ccccttatcc attactatac caaattagta aaaaaatagc
    26701 aattactatt gtcatttata ttaggaaaat attaaatctt tttaataaat atcttttttt
    26761 gacataagga ttacttaact tttaataaaa tagtaacact aatatgtatt aattaataga
    26821 ataaaataaa tgataattta ttgaggggtg atttacatgc caaatttgcc aagtttaggg
    26881 tcaaaggctc ctgattttaa agccaataca acaaatggtc ctattagact ctctgactat
    26941 aagggtaatt ggattgtttt attttcacat cctggtgatt ttacaccagt ttgtactaca
    27001 gaatttttat gttttgctaa atattatgac gaatttaaaa aaagaaatac agaactaatt
    27061 ggtctaagtg ttgatagtaa cagttcacat ttagcttgga tgtataatat ttctttactt
    27121 acaggtgtag aaattccatt tcctattata gaagatagag atatgagaat tgccaagtta
    27181 tacggcatga tatcaaaacc aatgagtgat acatcaactg ttcgctctgt atttattata
    27241 gataataatc aaattctaag aacgattctt tattatccac taactacagg aagaaatatt
    27301 ccagaaatac ttagaatagt agatgcactt cagactagtg atagagataa tatagttact
    27361 cctgcaaact ggtttcctgg aatgccagtg attttacctt atcctaaaaa ctataaggaa
    27421 ttaaaaaata gagttaacag ttgtaataag aaatattcat gtatggactg gtacttatgt
    27481 tttgtaccag ataattataa tgatgaagaa gtgagcaaga aaattgataa tacttgtagc
    27541 tggaaaaaag aacatactaa aaacattgaa aatgaatgta actgtgaaca tgaacatcat
    27601 gactacctga acaaagctct tgactgtaaa caagaacaca agactgatat taaagatgat
    27661 tgcaatcatg agaaaaaaca tactaaaaat actaacaaag ttcacaactc caaacaagat
    27721 aagtttaaag ataagtcttg tgatgaaatg aattttaact atgataaaga tgaatcttgt
    27781 gacaaaataa attctagcta taacaaagaa gatagtagtt atgaagattt ctataaacat
    27841 aattataaaa actacgatta tactagcgaa aaaaatacta aaaaaatagc tatgaaaact
    27901 ttaaaagatt ctaaaaaatt agttagacca caaataacag acccatacaa tccaatagtt
    27961 gaaaatgcaa actgtccaga tataaatcca attgtagcag aatatgttct tggaaatcca
    28021 actaatgtag atgctcaact attagatgca gttatatttg cttttgctga gatagaccag
    28081 tctggaaatt tgtttattcc ttatcctaga tttttaaatc aattacttgc tcttaaaggt
    28141 gaaaaaccta gcttaaaagt aattgtagct attggaggtt ggggagctga aggattctct
    28201 gatgcagcat taacacctac atctagatat aattttgcaa gacaggtcaa tcagatgata
    28261 aatgaatatg ctttagatgg aatagatata gactgggaat atcctggaag tagtgcatct
    28321 ggaataacat caagacctca agatagagaa aactttacac tcttactaac tgccataaga
    28381 gatgttatag gagatgataa atggcttagt gtagctggaa caggagatag aggatatata
    28441 aattcaagtg ctgaaataga taaaatagct cctataatag attattttaa tcttatgagt
    28501 tatgatttta cagcaggtga aacaggccca aatggtagaa aacatcaagc aaatcttttt
    28561 gattcagact tatctttgcc aggatatagt gttgatgcaa tggtaagaaa tcttgagaat
    28621 gctggaatgc cttctgaaaa aatccttctt ggtataccat tttatggaag attaggtgct
    28681 actataacaa gaacttatga tgagcttaga agggattata taaataaaaa tggatatgaa
    28741 tatagatttg ataatactgc tcaagttcca tatttagtta aggatggaga ttttgcaatg
    28801 tcatatgatg atgctttatc aatattctta aaaactcaat atgttcttag aaattgtcta
    28861 ggtggtgtat tctcatggac atcaacttat gaccaagcaa atatactggc tagaaccatg
    28921 tctattggta taaatgaccc tgaagtatta aaagaagaac ttgaaggtat ttatgggcaa
    28981 ttctaataga atgtaggaaa attttatagt tatataaaaa gcagatttta ttatattaaa
    29041 taagttgtat ctaattaata ctattattaa ttgtttataa attagatact tattttttca
    29101 taatacaatc tgctttttta atcaaaattt atttaattat aagttgttta attacaagtt
    29161 gtttaattac aagttgttta attataaagt aggaatttag atatactctt ataccatgta
    29221 attatgtata aatatttttt tattatacac caatagcttt tttagctaat ttatctgctt
    29281 cctcattata cttatttcca gaatgagctt taacctttgt aaattttaca ttaagcttat
    29341 tcttaatact gtcatagaaa tttttatatg ctatagttcc ttctttattt gttttccaaa
    29401 ctccagtaca ccacttttca atcccttcat agtcaaagta taaaatcaag ttttgaacat
    29461 tattgtcaat acagtactgc attgcaattt tagaagcctc tatctctcca gctacatttc
    29521 tcatacttac taaagttttc tcttttcctt tttcactata agtttttata acttcattat
    29581 tttttaaaat cacaacaccc gaaccataca tttttactga atgttcataa cttccatcta
    29641 catatgcttc tataaactcc ttatcttctt gaaaactcaa tttttctgac ccatcaatat
    29701 attctttagc ttcttgaaaa gtagaaaaac tcttatattc agctcctgag aatccattta
    29761 cttgtttttt gcactcatcc catgtattat atacacctat atttttacct tttttcacag
    29821 cataaaactt ttgttttgcc aaatatatca ctcccactct taatttttat cttcttctct
    29881 cataaatata tctaaattta taagatagtt tctatcaaaa tattttactt tcatatcttt
    29941 ttttataata tcaatatggt acacttctcc ttttacagct ctttgtctta tattttcatt
    30001 tatatctttt tttataatat ccttatcaac atcattgtta tccattttag catcaacatt
    30061 caacgctttt atagtatcaa atataacaga ttttagtatt aaacttctat atttatttaa
    30121 atgtcgcctt atataagtat aaaactcatt gctattaacc tttgaaattt tacaatcgtg
    30181 taaatctttc tctaatctct ttaacacact tatattagtt cctacatcaa aaatcacaaa
    30241 acatccatag tcatatttgc ttcttaaaat tctccccata gcttgcttta cctttatggt
    30301 catttgagga taatttatag tatagtagtc tataccatac ttcttcatta tagtaaaata
    30361 caaagggtct tttggattta gattcggaag cttgtctaaa gttacacaaa ccaaaccatc
    30421 ccctggaatg tctacgcctt caaaacatcc ttttgagcca agtactacac attttctatt
    30481 taaatcgtta aggtgtctaa tccccttttt atcagcataa atttctaagt taaaactatg
    30541 taagtatttt ttcaatattt cataagtttt ttcttgtcta tctttactat taaaaagagc
    30601 taatgtatga ccttctgtaa tctttgatat attagatata attttactca tctcatttgg
    30661 aaattcagaa tttctgtact cacaaatatc agaaaatcca actacagaga ctctattttt
    30721 ataatcaaaa attggttcta taatcttttc cacattctta actctgtcta ttcctaatgt
    30781 atttttaaaa taagacatac tttcagataa actcaaagtt gctgataaaa atattccttt
    30841 ttctaattga gataaaatat tttcttcaaa taaatctgct atttttaatg gcactactcg
    30901 aaattcaaag tcattataat tcttatcaat ttcaactatc cttgcataat catccttttc
    30961 atcatactct aaaaagattt caaatataat ctttatatcc tctaaatctc ttgtctttgc
    31021 ctttccaaat ttatatatat ctgcttcttt atctatacta tcatcatcaa tattcctata
    31081 aattattatt attattgaaa ctaaattttt tattattttc tcacaactca actttatctt
    31141 ttcactatag gctctataac ttatttcagt atctatacca tcctttttta gttttcccac
    31201 aatttcgtct atttgcaaat tcagttccca tcttaaatta taattactta cattattata
    31261 ttcattacaa ttaccaaact ttaatattga atctatctct tcaataatga gatttatact
    31321 tctagcaatt ttttgtttat cttctcttcc aatttttaat acattataaa atttatcaaa
    31381 agcctttatt tttctcatat ttctactata ttttttatat ataaagctac tattttgaat
    31441 aaactcgtaa ggataaattt cttgtaataa ataccttaaa gactttgaat ttataatgct
    31501 tgaaaagaaa tcatatcctt tttcagtcaa attatgtgct tcatctacta ttatattttc
    31561 taaaggtttt tcatccttat atggccattt agctaatagt gaatgattta ctactgttat
    31621 atgttcttct tttaattctt ctattctgtt tttatataaa caatcttttt tgcatttttt
    31681 aggtctgcac atatttgggt cacaacttac atttcttaag tgagtactta tttccttgaa
    31741 gttgtcaaac actaaataat ttatttcttc tatatctcca tacttgccac cttcaactaa
    31801 tctcttcaaa aatattaaag ataaaatttc tcctttagta gggttttgag actcataatc
    31861 atctatatat gcttccagtc tatctataca aatatagtta ttttttccct ttatatatcc
    31921 gtaacttact tttccattta gacccaaaga atctaacaca tttggaatat ctttatttat
    31981 taattgtatc tgcaattcct ttgtgtcagt agaaattaat aatctttttt tattaattct
    32041 agcctctaat attgcaggca ataaatatcc tacactttta cctataccag ttggtgcctc
    32101 tatacatgca attttttctt catcttcgct atttctaaac aactctctta ttgttttagt
    32161 aagctcatat tgaccaggtc tatattcata tgtaaatcct tctttattct cccaaatagt
    32221 tttgtatttt aataattctt cataattttt ttcttcttca tttaaaattt ttaaggtttc
    32281 tctttccttc ttcttttctt cttttgagtc aaatatatta tattcttttt ttatatttat
    32341 attatttgat aaatcataat ttgcctcttc taaaaatttg ctccattccc atgttggaag
    32401 attaaatttt ttaagatatg aatttatttt aaaactcaat ggctccaaag tagttttttc
    32461 atagttatta aattttacta aaaggcaatt tacaatattt attatatcaa tagcatctga
    32521 taaagctcta ttttccactt tagaattaca atttgttaaa gtatttttta agtattctaa
    32581 gctataatct ttatgatatg gttctaaaat aactgctaat tcaattaaat caataaattt
    32641 gttttttaac tttggcatat gatactcaag aaactttttt ttcagactta aatcatgaca
    32701 tataatgaaa ctatcttcta caaaatttac aagtctatct tccaccagtt ctatttcatt
    32761 agctatttct aaatcatttt tatctaaatt tttacatact gagaatactt ctacaggtac
    32821 ctcaaatttg ttttttatta atgattcata ggtatatatt ttccagtctt taaccttgac
    32881 agctccaact tctaaaattt ctgaatttaa acaatctaat ccactaactt ctatatctaa
    32941 aaaaacaaca tcattcaata cacttattat attatccatt tttatatccc ttcaagttaa
    33001 accagcctaa cttatttaca atcatttctc tttatatttt atcatttata tacactttat
    33061 ttaagataat taatatcaac tttatatctt acagtaaact tctttcattt attatttgta
    33121 tatgtgaata tttttaacta taaatattca aactatatta taagaaatat actttaaatt
    33181 ttaaataaga ggtgaaattg tgaaaaaaga tagcctaaaa aaatacatta tgataggagc
    33241 atttgctcta atactttttg gaattgctag tataaatttt aaatcattag ataaaacaaa
    33301 aactcaaatt tctagtccaa cactcgacac acatgaatat gattggtatt ttaaccctag
    33361 ggaggatggt aaacagccat cacctataaa agaagctgat ttttttaaaa aatacggagc
    33421 ttattatgta ggaaatccca atgaaaaagt tatatatcta tcatttgatg ctggatatga
    33481 aagtggaaac actccaaaat tattagatac gcttaaaaaa cacaatgcta aagctcaatt
    33541 tttcgtagtt gaaagttata taaaaagcaa tccagagtta ataaagcgta tggaaaaaga
    33601 aggacattta gtttgtaatc attcaaaaag ccatccatca atggcaggta ttacagattt
    33661 tgaaaaattc aaagaagaaa ttacaagtgt agaaaaagca tacaaagatg ttactggaaa
    33721 agaaatgcct aagtatttta gacctccaat gggtaaattt agcgaacaat ctttaaaata
    33781 tacacaagat ttaggatata aatcaatatt ttggagtttt gcttatgtag attggtatga
    33841 aaagaaacaa cctactcatg aatttgccaa aaacaaaatt tattcaagaa ctcatcctgg
    33901 tgcaatagtt ttactgcatc caaattcatc aacaaatact gagatattag atgaggttct
    33961 tacacattgg gaaaaagaag gttataaact taaaacactt gattatttaa ataataaaaa
    34021 atagtatcat aaatttaaaa aaactctatc atgaattata gtaaaaatat agttatttat
    34081 aaatacttta attctcgata gagtttttta ttttttatag ctatttaaaa agaattgtcc
    34141 attcatttat ctctttgtat cctatattat gatatatttt acctgctaca tcattattat
    34201 aaaaaagaca tggaactttt ccttctaaca acaattcttt actcaaattg taaaccatat
    34261 aacttgcaag tccttttccc ctatatcttt tatctgtact tacagagacc accattgcca
    34321 aaaaactagt ttccatacca gttgacacag tgctaatcat agtatcatca tttctaataa
    34381 aatatgctct tacatttccc tcttttaaat gaacttttct ttcttctatg taatttttac
    34441 ttactttata gtctgaccta tttaaaagtt ttcctatttc atcaatatct ttttcctgag
    34501 cattttctat tttatactcc ttcatgttgg aaaaatctat ttcttttatt tcttttaata
    34561 cacaaaattt attatctagt ttttcataaa aatctttgta tttacttatt agtctatcta
    34621 ttacacattt ttttccactt atgctttcta catctaaatc ttttatatga ttcttcattt
    34681 ctcctatatt aaaattattt ttaaaactat aaattataag tgttgactta ttttttaata
    34741 ttatagaggt tatatttcca tcttctacct gagaccatat atcttgatat tgagagctaa
    34801 atccataatt ctcaacgtat ccaattatga ataaatttaa actttcttca tgtgatacat
    34861 attgccaaaa ttctttttct aaagtattat ctatttttac aatcaagcag atatcctcct
    34921 tctatgttaa taatgatata ccttataatt tatagtatca tttaaaatca ttatattcta
    34981 ccaaatattc taaattttta aatatctatg caatatgttc gtatttattt ttatattctg
    35041 ttactgcttc actccaagct tcttctactg aaatacctct cttatttgca attttttgtg
    35101 ctaattctat tattttcata gcttttcttg atatattcat atatattcct cctctaaatt
    35161 atcataagtt attttaaagt taaatttcta tagtcatgtt atatatttat ttacttatat
    35221 cttactaatt atttatgtac taaatatgaa ctacaataga agaaatttag aacttaataa
    35281 aacataaaat ttatatacag ttcatatata tttgtcatat cacaagacaa gtgatataat
    35341 ttattatcat tttactgggg gtgatatgct atgaaaataa gagctgaata tacatgtctt
    35401 cttgaaattg tacatgacat aatcaaagga aaatggaaaa ctatccttat atttgaatta
    35461 agacaatcta ataaaacatt ttctgaattg caacataata tttatggaat aaatcaaaaa
    35521 atgttgattc aacaattaaa agagttacgt gattttggga ttattgataa aataagttct
    35581 gctggatatc cattacatgt tgaatatttt cttactaatc gtggtaaaaa aatgttaaaa
    35641 gcagtggaaa taatgcaaga aataggaatc gaatatatgc ttgaacatgg tcaacaagaa
    35701 attctagata ataaaggaat ttgctacaat aagtaatcct atacatacca aaaagtaagt
    35761 aatttacatt ttttacaata gtattataat aaaaataaat aggaggtata atcatgtcta
    35821 tagctttaat attgattgat attcaaaatg attattttaa aaatggaaaa tgtgaattat
    35881 ttcaatcaga agaaactgct gaaaatgcta aaaaaatact actgtttttt agaaaaaaca
    35941 atttaccagt tattcatata cagcatatat caacagataa aacagcttct ttttttcttc
    36001 ctaatactca tggttcagaa ataaataaaa ttgtttttcc actagataat gaagaaatta
    36061 taactaaaca cacaccagat agtttctttg aaacagattt gcaaagtatc cttgagaaaa
    36121 aaaatattac taatctagta atctgtggaa tgatgagcca tatgtgtatt gatacaagtg
    36181 taagaacagc aaagaaactt cgatacgaca taactctaat aagcgatgca tgtacaacga
    36241 agaatttatc ttggaataat atagaaatta atgcaaatac tgtacatcaa gtattcatgg
    36301 catcactaca gaacagtttt gcagatgtaa aaaacacaga taaattttta tctaactatc
    36361 acaaataaaa acatacacta tgttaaaaga gcaagtttga tttatttaag cttgctcttt
    36421 aatcatttaa aattagatgc tttctatcat ttttatatac ataatatacg tttatacatt
    36481 ttatattcat atataactat tatataaatt ttaaacttta ctatattcac ataaaaaatg
    36541 tagtattata gtatatataa tattatatag aagggggtgc tagataaatg aaccatcata
    36601 tattgattca atttgaatat atagcaagaa tcattactgc tggtttctgt ggggctttaa
    36661 ttggatatga gagaaagaat agactaaaag aagctggaat acgcactcat tttatagtgg
    36721 cattagcttc agcacttata atcattgttt ccaagtatgg atttaatgat atagtgggta
    36781 ctccaggtat tggtctagac ccagcccgcg ttgcagcaca agttgtcagt ggtataggtt
    36841 ttttaggtgc tggattaata tttattagaa atcaatcagt aagtggtctt actacagctg
    36901 ctggtatatg ggcaacagct ggtacaggtc ttgccattgg ctctggatta tacttagttg
    36961 gtattgtttc aagtatcatt attgttattg tacagataac acttcataga gataggaaat
    37021 ggatgaaact ccctacagca gagcaagttt ctcttaaaat ttctaacagc actgattcca
    37081 tagaatatat tgaaggtaaa tttaaaaaat ctaatattga aattataaac atgaatatta
    37141 aacgccttga tggggattgg ttagaagtag ttatatatac taagttacct aaaggatata
    37201 aaaaaacaaa tttattaaaa ttatttagcg ataatcctct tatagaaact ttagaaatat
    37261 aatataaaaa ttgaagctta aaaataataa tatatttaat caaggtcaat atataaataa
    37321 ttacgggatg agtctatata aaattcatcc cttgtttttt gccattcata tatatttttt
    37381 caagatattt ttgttcatct attatctagc caagtaactc ttgtgaacta aactttttaa
    37441 tacaaaaact tcaatacaaa actaaatata atttttatta aatattctac atgtatagtt
    37501 tatttcttga gtgaaaaata gatttcatat tgttaagata ctgttaaata tttcaatttt
    37561 ctgacaagta tgttgaacaa taacttatcc tagtgtatta ttttagttgt agaataaaac
    37621 taaatcggca aaactagaga aatttagtga cgcaaagcta tagggactaa cgcttataaa
    37681 ataaactatg agttatgtca gccagttgcc aaaaagatat tgttcttttt gttttatgaa
    37741 agttttttag ggggatagta atatatatgt ttagagatga aatggataaa tgtacacaca
    37801 tgttaactgc ttatatcagt agtttatatg attattgtga ttttatagat acacagctag
    37861 atgattttat actagagtac ggagaaaatg tagtagaatc ttgtttacat caagtgatgg
    37921 tattggtaag taagtataat taaatagaaa ttgttttcta gagaaccctt tttagtttta
    37981 tctacattta aaaatgttat tatattaaaa aactaatctc ccctatatgc aaagttttct
    38041 tccatataac aatttcttcc catttatact ttttcacttg tatctttaat aaaattcaac
    38101 ttcaaatatt aatatacttc aaaaattatt ctatttctta tctttacacc aattcctatc
    38161 agtattatcc tttatatagg ttctaactat ttctccacaa tctaaacata aatctgaata
    38221 tatagtagat tgtactggaa aagttttatt tataacttta tctaattttc catctcctct
    38281 atattttaat ccaatagttt cagcatatat gccaccagtt gttaaaattc ccttttcaat
    38341 atttacactt ccacaattag aacatttcac atttataacc ccctaaacaa ttattttttc
    38401 atgctatctt ataatttaaa atataatttg ctaccgattt tataacacag tggcaaatca
    38461 acattttttc attctattta ccatctaatc cattgaaata tagctattta gttataggaa
    38521 cttgaatttc cgttacaaac tcctctacaa ttccagtctc atgtatatct atcttataga
    38581 tttctatagg gtcagcaatt atcttataat tattttcttc tataaattta aacaccttct
    38641 ccatatatat cttattatta gaattactcc cagtataatt taaagttaca taatatcctt
    38701 catcaaaaac tatattatat actttctcat tactttccag aaaacaaaat acagatttaa
    38761 actcattaaa tataccttta ttaattgctt cagtagaaaa ggcagaacca atattgttgt
    38821 ttccaagtat attaaatcta tcttcatatt ctttctgaag tttttgaatt aaaaaatcga
    38881 agtcttcatc cctctttata tcagcattta attctaaagc ttttcttttt tctatatata
    38941 caacctctat ctcatctatt tttgtatttt gaattacact ttcaattgaa ctcaatcttt
    39001 ttataatatt ttccttatgg cttataaatt cagctatttt tttatcaatt aaatcgagtt
    39061 cttcatttaa aatatttttc gtagactcta tacttctgtc atctaggtat tcttttattt
    39121 tcttcattgg aaagttcaag cttctaaatt cttttattaa atttaatttc catatatctg
    39181 atatattata cattctatat ccatttatat ctctaactgg tcttagaatg cctatttctt
    39241 cataatacat taatgaatct ctacctattc catatatttt agatatctct cctattttat
    39301 agtaatcttt catttatata ataaactcct ccgaaatctt atttttattt taaatcaaca
    39361 ttattactct ataatactat agtattagaa tatactaa
//
LOCUS       DAMJVG010000035        38956 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.035, whole genome shotgun sequence.
ACCESSION   DAMJVG010000035 DAMJVG010000000
VERSION     DAMJVG010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 38956)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38956)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38956
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.035"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            119..769
                     /locus_tag="PC512_001899"
     CDS             119..769
                     /locus_tag="PC512_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic nucleotide-binding domain-containing
                     protein"
                     /protein_id="HDF2441641.1"
                     /translation="MKAEKTSIYPIIKNNLNKISIVEYKKGQRFVASDKDLQEVFFII
                     EGVALVECTTRGGNKFLVDIVPENEFIGKISYIYEHNLKCDIFAKTNIKLFRFEKNVF
                     EEFYLKPDFIALFHRKCTRRIYELYKTRMVRELFSCTEVIAYCISNKQENNVCNIKAI
                     RNFSEIYSISRKSRYHSLLKLTEKEIVKKMGNTYEILNYDELHKLAFEVKEFLEDE"
     gene            complement(909..2285)
                     /locus_tag="PC512_001900"
     CDS             complement(909..2285)
                     /locus_tag="PC512_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2441642.1"
                     /translation="MQELFSLKDENKRFYKILLSLCIPIIIQNLISTSVNVIDTIMIS
                     SLGETSVASVGVANQFFFLFNMSLSGITGGAGVFISQFYGKKDVSNIRKVTGLTCVLA
                     IVLSFVFVIPALLTPKPIIHIFSYDSEVVKLCIDYFSIAVFSYPLIAVSTVFSTGSRG
                     VRNPKLGMICSAFALVTNVILNYGFIFGNFGLPALGVKGAALATVIARICELILMITY
                     VYLYKKDYILKFGLKNLKAIDKIFIKSFSSKSFPIFVNDSVWAIGTVLYSVAYARAGT
                     SAIAASQIATSTGNFFIMTAVCIASGASIMLGNELGADHIKRAIEYAKKFSILVFSAG
                     LILGIILILNIPLLLKMFSVSDSLASDITKIFFIMGILMALKSFNTLVIIGILRSGGD
                     TKYALFLELGCMWLASIPLTFIAAFKGAPIFVLVLLTYSEEVVKFIFGVPRALSKKWA
                     INIVKEID"
     gene            complement(2301..4214)
                     /locus_tag="PC512_001901"
     CDS             complement(2301..4214)
                     /locus_tag="PC512_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDF2441643.1"
                     /translation="MIVLSCNNLNKSFGIDSILENISFTVNEGDKIGIIGVNGTGKTT
                     LFKIISGIYGYDSGDIYTSKDCEIGYLEQNTNFYSDNTILEEVLEVFKNLIEMESYLR
                     ELEVKISEESTKTNSPIIEKIMDEYSHKLELFSDLNGYGYKSEAKGVLKGLGFSDNDM
                     DKPISILSGGEKTRVLLGKLLLKKPTLLLLDEPTNHLDSEAIEWLEVFLKQYKGTVML
                     ISHDRYFLDQSVNRIFEVHNKKLKVYNGNYSKFVELSKIEKELELKKFEDQQKEIKKQ
                     EESIERLKAYGREKHLKRARSKEKALDKVDVLDKPEAYRKKARIQFTPSVQSGNDVLQ
                     IRDVSMGYGERILFKDLDLDIYRGEKVALIGANGVGKSTLFKIITNELQPLSGNIKFG
                     TNVHVSYFHQEQKTLNLDNTIIDEIWENNTHLTQTTLRNMLGAFLFVDEEVFKKISTL
                     SGGERARVAILKLILSNANLLLLDEPTNHLDIDSKEVLEEALTNYDGTIFTISHDRYF
                     LNTVVDKILVLDENGITEYLGNYDYYIDKKRQIQEMSIIEEKEEKTRTQIKDEKRKER
                     EQREIEKKNRIKRQNIEKEIEKLEIEIEKLDILLCQEEVYSNPDKAKEVSQEKINLEN
                     NLASLYDEWEEFM"
     gene            4350..4982
                     /locus_tag="PC512_001902"
     CDS             4350..4982
                     /locus_tag="PC512_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HDF2441644.1"
                     /translation="MLGNKNISMAVIRRLPKYHRYLGDLLDRDIQRISSKELSDIIGF
                     TASQIRQDLNNFGGFGQQGYGYNVEALHTEIGKILGLDRPYNAVLVGAGNLGQAIANY
                     AGFRKAGFEIKALFDANPRMIGLKIREFEVLDSDTLEDFIKNNNIDIAVLCIPKNGAQ
                     EVINRVVKAGIKGVWNFAPLDLEVPKGVIVENVNLTESLFTLSYLMKEGK"
     gene            5121..5660
                     /locus_tag="PC512_001903"
     CDS             5121..5660
                     /locus_tag="PC512_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA C4-type zinc finger protein"
                     /protein_id="HDF2441645.1"
                     /translation="MVFVEELWKKAIEFHGHECPGLAIGFKAALAAKKYLGCKQSGDE
                     EIVCISENDACGIDGIQVVLSCTMGKGNLLLRMTGKSVYHFFNRENGKSIRIYVKSKP
                     FEMDREGYKRYLLESDFEEIFEITDTKLRLPEKARIFKSLKCEVCGEFASEQYIRIEE
                     GKKVCLDCFDKYERFYEEY"
     gene            complement(5836..6006)
                     /locus_tag="PC512_001904"
     CDS             complement(5836..6006)
                     /locus_tag="PC512_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004619190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF2441646.1"
                     /translation="MAYKITDACISCGACEAECPVSCISAGDDAYVIDAGSCIDCGSC
                     AGACPVDAPQPE"
     gene            6291..7358
                     /locus_tag="PC512_001905"
     CDS             6291..7358
                     /locus_tag="PC512_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HDF2441647.1"
                     /translation="MKNKLVYICIMSLLLFVVGCSNNPNKESTIKKDSKNNQSQVKEE
                     KREPVKKDITISFAGDVTMGNYKGSSYYGSFDHEFKRQGEDYNYFLKNVKPVFEKDDL
                     TVVNLEGPLTTASNAKEKKFAFKGKPGYVNILKSGSVEAVSIANNHSEDYFEEGMKDT
                     QFILDENKINYFGLGKDAVVDVKGIKVGLLGYNGLSTEYNEKNLKQMEDDIKSLKKKS
                     DVVVVYFHWGIELDYYPDKKQKDFAHYAIDKGADLVMGSHPHVIQGIEKYKNKYIAYS
                     LGNFCFGGNKNPSDTDSYIYQQTFTFSDNKLTSIKEPNIIPTSITSSNSRNNYQPKIL
                     DGSEKDRVLNKLEKISKDLNK"
     gene            7528..9429
                     /gene="cooS"
                     /locus_tag="PC512_001906"
     CDS             7528..9429
                     /gene="cooS"
                     /locus_tag="PC512_001906"
                     /EC_number="1.2.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic carbon-monoxide dehydrogenase
                     catalytic subunit"
                     /protein_id="HDF2441648.1"
                     /translation="MACNTCKMCESADKKLESFVASKDVETAFHRTEDQKVKCGFGLQ
                     GVCCRLCSNGPCRVTPKSPRGICGADADTIVARNFLRAVASGAACYLHVVENTAKNLK
                     NVGITKGVVKGEKTLNQLAEMFGIESDEKYDKCIKVADKVINDLYKSRDDKMELVEKI
                     AYAPRVKKWKELGIMPGGAKSEVFDAIVKSSTNLNSDPVDMLVNCLNLGISTGLYGLT
                     LTNLLNDVMLGEPVIRMAPVGFNVIDPDYINIMITGHQHSTFANFQDRLKDEDVIKLA
                     QSVGAKGFKLVGCTCVGQDLQLRGEHYQEVFAGHAGNNFTSEAVLSTGAIDIVLSEFN
                     CTIPGLEPIADKYKVKMVCLDDVAKKANAECIGLDRSKLDELSNTLIEKALESYKERR
                     GSIEIDIPKDHGFEQSLTGVSEKNLKAFLGDSWKPLINLIAEGKIKGVAAVVGCSNMT
                     AGGHDVNTVELTKELIKKDIIVLSAGCSTGGLENVGLMSPGAEELAGENLKEVCKTLG
                     IPPVLNFGPCLAIGRLEIVATELAAELGIDLPQLPLVLSAPQWLEEQALADGAFGLAL
                     GLPLHLALPPFITGGKLVTEVLTEKLKDLTGGHVIVNPDPKSSANQLEEIIIDRRKNL
                     GLKDVECNA"
     gene            9422..9895
                     /locus_tag="PC512_001907"
     CDS             9422..9895
                     /locus_tag="PC512_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HDF2441649.1"
                     /translation="MHRIFINKDLCTGCKSCVLACMLKHNKDYDMYTLDLENIDNDSR
                     GHIELDSRHNNPVPILCRHCDEPECVLACMSGAMHKDSESGIVSYDEEKCGSCYMCVM
                     SCPYGLLKPDDRSKQNILKCDLCKDEEYPRCVANCPSGAIELQKEENDELCSVRG"
     gene            9870..11096
                     /locus_tag="PC512_001908"
     CDS             9870..11096
                     /locus_tag="PC512_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDF2441650.1"
                     /translation="MNYVVLGASAAGINAVKTLRELDKDSNIVVISKDENVYSRCMLH
                     HVISEHRTLKQINFVDEDFMEQNNVKWIAGKTVKGIDINKKVVQTEDITVNYDKLLIA
                     TGASSAIPPIKNLRDGNFVYSVRNIDDIYKIKEKAQNSKNVVIIGAGLVGIDALVGLF
                     KYEQLNISVAFMEKYILDRQLDEYTASVYENKFKEKGVKFYPSASIQEIVLDNSKNVT
                     GVAFSNGEVLDADMVIVATGVKPNADFLDGTGIEYDRGIIIDDMCQTTQKDIYAAGDV
                     VGKNAIWPLAVKQGIVAAYNMVGKDKKIEDEFAFKNSMNFMDIPTISIGMNTPVDDSY
                     KVLTRHGINDYKKFVFKDNVIYGAVIQGDISYVGVLTYLIKNKVEIYDLENRIFDICY
                     ADFFNIKENGEFCYSV"
     gene            complement(11235..12422)
                     /locus_tag="PC512_001909"
     CDS             complement(11235..12422)
                     /locus_tag="PC512_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDF2441651.1"
                     /translation="MNITKNFLKDYLEKFGETPFLVRLKDEEEFLIGEGSPQFKVIVN
                     NDISKSELLKSTSLALGEAYINRDIEVEGDLFLTLNLLLKQIDKFNIDNSAVKHLLHS
                     SNSMRHQKKEIHAHYDIGNDFYSLWLDKTLSYSCAYFRNDNDTLYDAQVNKVHHILTK
                     LNLEEGMSLLDIGCGWGFLLIEAAKKYKIHGVGITLSEEQFKEFNARIKEENLQDYLE
                     VRLMDYRELKKSDLMFDRVVSVGMLEHVGRENYELFIKNVNAVLKDGGLFLLHYISGL
                     QESYGDPWIKKYIFPGGVIPSLREMIHICSDYKYHTIDVESLRLHYVKTLLYWQKNFS
                     ENLPKIKEMFDDKFIRMWDLYLCSCAAAFNTGIIDIHQILFTKGIKNDLPLTREYMYN
                     CSK"
     gene            12695..13519
                     /locus_tag="PC512_001910"
     CDS             12695..13519
                     /locus_tag="PC512_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HDF2441652.1"
                     /translation="MEVYALVGSSGTGKSFKALEFAYENDIEYIIDDGILIYKNKVLA
                     GISAKQANTTIEAVKRAIFYNLEHRQEVREAIKKENIRKILIIGTSKKMVNQIVERLS
                     IGRVCKFINIQDISTKYEIEIAKQARKEGNHVIPVPAVEIKSMASGLSINSLKRLFRK
                     GNNRNMVVLEKTIIRPTFSYIGKFYISADVIKQIIEYEVYNFGSIDRINKINIENCNN
                     FMNIFVSININDLETIKKIEDIQQTIKKSIEKMTLVNVQKIDINIHKIKKINFLQC"
     gene            13648..14913
                     /gene="gluD"
                     /locus_tag="PC512_001911"
     CDS             13648..14913
                     /gene="gluD"
                     /locus_tag="PC512_001911"
                     /EC_number="1.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-specific glutamate dehydrogenase"
                     /protein_id="HDF2441653.1"
                     /translation="MSGKDVNVFEMAQSQVKNACDKLGMEPAVYELLKEPMRVIEVSI
                     PVKMDDGSIKTFKGFRSQHNDAVGPTKGGIRFHQNVSRDEVKALSIWMTFKCSVTGIP
                     YGGGKGGIIVDPSTLSQGELERLSRGYIDGIYKLIGEKVDVPAPDVNTNGQIMSWMVD
                     EYNKLTGQSSIGVITGKPVEFGGSLGRTAATGFGVAVTAREAAAKLGIDMKKAKIAVQ
                     GIGNVGSYTVLNCEKLGGTVVAMAEWCKSEGSYAIYNENGLDGQAMLDYMKEHGNLLN
                     FPGAKRISLEEFWASDVDIVIPAALENSITKEVAESIKAKLVCEAANGPTTPEADEVF
                     AERGIVLTPDILTNAGGVTVSYFEWVQNLYGYYWSEEEVEQKEEIAMVKAFESIWKIK
                     EEYNVTMREAAYMHSIKKVAEAMKLRGWY"
     gene            15126..15716
                     /locus_tag="PC512_001912"
     CDS             15126..15716
                     /locus_tag="PC512_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M56"
                     /protein_id="HDF2441654.1"
                     /translation="MHFKSKDLNLKYLVLFLKIVYWFNPFICIMEKYMDLDCELYCDE
                     RVLKNCTVQQKQEYALTIVNSMKRSTNFSNKFVAGLNKQSDIRKRVINMFSEKHKNGI
                     LRALIISLFSSITFFKFDSTSIIEENDFLERSRYTFEGRQEDMFVTIDFIYADVPIKL
                     RKEHEENCRVNGIVPKDSDSIEIIPRFYKDCMDLKK"
     gene            16046..17179
                     /locus_tag="PC512_001913"
     CDS             16046..17179
                     /locus_tag="PC512_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M56"
                     /protein_id="HDF2441655.1"
                     /translation="MSNFILNGIFRTVIVSSLSILLILIFKKNVFKRFSKKFNYYIWM
                     IVVIKLFLPFTYYTFTINILRSKKHININNINLEGFNNVSTISNNIILYTWIITVVVY
                     LIYTIFKYIKLKNLINDLSYDVDDREIVNLYKNILEEFNITKDIKLKYSYEVETPAFF
                     NSCVLLPPHEYKLKELDWIFRHELMHFKSRDLYLKYVILFLKTVYWFNPFIYIMDKHI
                     DLDCELYCDERVLKNRNSEEKKDYALTILNAMRKGSNTSNKFIAGLHKQSDIKKRVMN
                     MFNEKYKNGILMALTLCLLSSITFLKVNSTSIVNLNVLPKGFEDLRTVSSIRFSVIGF
                     TYADAPKNMREEYKINCESLGLIPKDSDKIEVGIEYYDSLLND"
     gene            18095..19117
                     /locus_tag="PC512_001914"
     CDS             18095..19117
                     /locus_tag="PC512_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HDF2441656.1"
                     /translation="MKKKILIPVFASVMALSVSSIVNADEVNDSSQNKDDKTNTELNL
                     GEYKEVKYKVAKIKDGVAIKIREEGQVQNIAYSGDEFTVLGTQGEWVKVKVEDGEGWL
                     ATRYVDISEGVGYTNADKVNLRKDKSESSEVIEELEKGSSLLVLEDNGDWLKVKDGET
                     EGYVKSSYISDKAPVIEEPQVNPSIDQNVDSTNNNQQNNANTNQQNNNSNVPTANSNA
                     VQAVLNLAYSKQGCPYVWGAEGPNTFDCSGFTQYVYRNAVGKNIPRTSKAQSKYGQTV
                     SKANLQPGDLVFFTTNGSGSVSHVGIYVGGGNMIHSPSTGKTVSVTSINSSYYTARFV
                     TAKRIL"
     gene            19414..20334
                     /gene="pyrB"
                     /locus_tag="PC512_001915"
     CDS             19414..20334
                     /gene="pyrB"
                     /locus_tag="PC512_001915"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase"
                     /protein_id="HDF2441657.1"
                     /translation="MLKSRNLIQPEDFSIEEIDEILELAQKIIDNPSKYSRICEGKLL
                     ATLFYEPSTRTRLSFESAMNRLGGRVVGFSEPNSSSASKGETLGDTMRIVSGYVDIIA
                     MRHPQSGAASEAARYTEVPFINAGDGKNQHPTQTLTDLLTIKSLKGTLESHTIGLCGD
                     LKYGRTVHSLVKAMARYKNTKFVFIAPEELKMPDYIKEAIKGHAYYETNNLDDVIGSL
                     DVLYMTRVQQERFEDKSEYERLKNYYILNKAKLEKASKDMLVMHPLPRVNEIDIDVDS
                     DDRAVYFKQAKYGMYVRMALIIKLLGINED"
     gene            20373..21065
                     /locus_tag="PC512_001916"
     CDS             20373..21065
                     /locus_tag="PC512_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HDF2441658.1"
                     /translation="MYKILENIYIGEDMYRMKVKGNFEGKMGQFYMLRAWDTYPVLSR
                     PISIHDIDEEGITFLYKVVGEGTQILSNLKVNDTIKLEGPYGNGYAKVDGKVALVGGG
                     IGVAPLYLVAKNIKNCDAYLGFREDVILEDEYKQVCNKVYTTVGNTFVTDIIDVEKYD
                     YILTCGPTPMMEKLVKMVEGTKTRIMVSLENHMACGVGACLVCTCKTNGGNKKTCKDG
                     PVFWGEDVIFNG"
     gene            21058..21960
                     /locus_tag="PC512_001917"
     CDS             21058..21960
                     /locus_tag="PC512_001917"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HDF2441659.1"
                     /translation="MGNLSVKFGSVEFKNPVIMASGTFGFGKEYNEIYDIQKLGGISS
                     KGLTLNKKPGNNGMRVHETPSGMMNSVGLENPGVQGFIDYELPFFSKLDLVRIANVGG
                     GTLEDYLLGVQMLNDKPIDIIELNISCPNVKAGGMAFGIKNEVAREVVREVRNITKLP
                     LVIKLSPNAEDIVGMAKVCEEEGADGVSLVNTFKAMAIDIKNRRPVFENVYAGLSGPA
                     IKPIALRMVHEVCKNVNIPVMGMGGITKATDAIEFIMAGATCIQVGTANFMNPRIGIE
                     IIDGINEFMDREGIKSLDEIRGII"
     gene            22045..22629
                     /locus_tag="PC512_001918"
     CDS             22045..22629
                     /locus_tag="PC512_001918"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HDF2441660.1"
                     /translation="MSKVDVVDILKKSDALLEGHFLLSSGKHSNRYVQCAKVLRFPEY
                     AAEVLSTVVEQIKDLDIDLVVGPAMGGVIVSYELGRQLGKEAVFTERKDNTMELRRGF
                     EVKKGAKIIIAEDVVTTGKSTMETKRVLEALGGEVVGVACIADRTNHDIGMPIYSAIK
                     LDIQVYESDECPLCKEGKLPVVKPGSREFKELGM"
     gene            22844..23770
                     /locus_tag="PC512_001919"
     CDS             22844..23770
                     /locus_tag="PC512_001919"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HDF2441661.1"
                     /translation="MKNQLNENHKKVVFFGVGAVGATFAEQFFNSKYDFKILCDNERK
                     KRYLEEGFIINGKRYDFDYVTKDEYKQEADFIIIGLKYNNLKENIKELDGLVGKNTVI
                     MSLLNGVDSEEIIGERFGIEKMVYSYVTNIDAKKINNNIIHTTNGIIVFGNKDNSEDR
                     KTNIITEVFDDVNIEYTLSKDIQRDMWWKYMVNIGVNQTSAILGAPYGVFQSSEHLRE
                     LAKSAMREVVAIAQAKDISLTEDDVEHSLHRILEHSKEGRTSMLQDVEAHRLTEVDMF
                     SKNICKLGKKYNIPTPINQTFFYMIKVIESRF"
     gene            complement(23822..24712)
                     /locus_tag="PC512_001920"
     CDS             complement(23822..24712)
                     /locus_tag="PC512_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF2441662.1"
                     /translation="MFEELKTFVAVVEYKNFTKAGEYLNLSQPSVSKHIKNLENYFKV
                     VLINRSIKQKTIFITESGQILYKRAKEILNLLNITYHDVSQVSDAITGHLKIGASLTI
                     GEYILPNFLALFSKKYPDIDVEVFIKNTSIVSSHVKDYILDIGLIEGTCSSPSFIQEY
                     FFEDKMVLALPYKSHLLKDFSFDKLQNQKWIVREDGSGTRDYLDMFLSVKEIIPKSMM
                     VFGSNYAVKESVRNNLGITIVSNLVTSLPVLNNELSVIELGSSYNRHFSYIFPKDITL
                     SKAATIFIEELKIFSNLNSI"
     gene            24900..25931
                     /locus_tag="PC512_001921"
     CDS             24900..25931
                     /locus_tag="PC512_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HDF2441663.1"
                     /translation="MLKKKSSLTLKTIREILPGLFVSVLVGYISIFISILIPKVGAAS
                     ISIFLGMFVGNLFLNQKVFQKGYKFSETDLLSYSIVLLGATLSVSTLIDLKVSGILFI
                     ILQMTITIIAALYIGKKLGFEENFRFLMASGNAVCGSSAIGATVPVVNATDKEKGIAV
                     TIVNVTGIFLMFLLPIISQFLYSHELVKTSAMIGGTLQSIGQVVASGAIVGENVKDLA
                     TIFKIVRVIFLVVVVLVFGHMKNQSNREILEEEKDEIKKKKVTIPWYVIGFFITCALF
                     SMNIIPQEVSVLCKEISNKLEIIALAAIGLKVNVKDLVKQGKEVSLYGLFVGIVQVVS
                     AVVLIKIFI"
     gene            26225..27100
                     /locus_tag="PC512_001922"
     CDS             26225..27100
                     /locus_tag="PC512_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA glycosylase"
                     /protein_id="HDF2441664.1"
                     /translation="MNVYEKGNGVILEGVTDFDPVHIFECGQCFRWHKQEDGSYTGVA
                     KGRILNVKKENDKIYLNNTNLKEFNSIWYNYFDLGTDYTEIKNKLKNMDEYLNKATEF
                     GWGIRILRQDGWEMLISFIISSNNRIPMIQRAIENLSRKFGKYIGEYEGNEYYAFPTP
                     EELNKASQEEIRACQTGFRDKYIKSTTQAVIENNDEVSEYTNLSTEDCRKELLKFNGV
                     GPKVCDCIALFGMQKYDSFPVDVWVKRVMQEFYIDEDMSLPKMRTYGIDKFKEMSGFA
                     QQYLFYYARELGIGK"
     gene            27118..28608
                     /gene="cls"
                     /locus_tag="PC512_001923"
     CDS             27118..28608
                     /gene="cls"
                     /locus_tag="PC512_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HDF2441665.1"
                     /translation="MGVIGTIFLFYLIISYLAGAIISVIILLENRDPAKTMSWLLMFI
                     IFPGVGLMIYAISGRNIRKRKLFKTQKLANNIKEKKLFDTLEKITEIVELEKESIKQN
                     KLLRDEEDGSYRKRVINMLLKTGMFPFTKNNKVDVFVDGNEKFKRLIEDIREAKDHIH
                     LEYFIIKDSEIGRVLKEELIKKAKEGIKIRILYDDVGCWRFWFNRKFFREMREVGIEI
                     AAFLPTKFPIIGGKLNYRNHRKIVVIDGIIGYTGGINIGDEYLGKNDKFGYWRDTHIR
                     IKGISVYMLQMTFLIDWYYTTKEVLVTKNYFPSVGNVGESMIQVVASGPDSDWEDIHY
                     AYFSAICQARKNVYIETPYFIPDESLLKAIKSAALSGVDVRIIFPKIADHKIVNIASY
                     SYFEEILRAGGKVYLYNKGFIHSKVVIIDDKIASAGTANMDLRSFMLNFEVNAFIYDE
                     EVIRVMTDDFFEDLSHCEELNLEVFKNRNIIQKIKESVARLFSPIL"
     gene            28801..29085
                     /locus_tag="PC512_001924"
     CDS             28801..29085
                     /locus_tag="PC512_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012062101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HDF2441666.1"
                     /translation="MKIRPLADRVVIKKVEAEEKTASGIVLPGAAKEQPQIAEVVEVG
                     PGGIVEGKEIKMELTVGDKVIFQKYSGTEVKIEGQEYTILRQSDVLAVIE"
     gene            29118..30746
                     /gene="groL"
                     /locus_tag="PC512_001925"
     CDS             29118..30746
                     /gene="groL"
                     /locus_tag="PC512_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729227.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HDF2441667.1"
                     /translation="MAKEIKFSEETRRALEAGVNKLADTVKVTLGPKGRNVILDKKFG
                     SPLITNDGVTIAKEIELEDRFENMGAQLVKEVATKTNDVAGDGTTTATVLAQAIIREG
                     LKNVTAGANPILLRKGIQKAVTVAVEELKNQSRIVETQEAISQVASISAGDEEVGKLI
                     AEAMEIVGKDGVITVEESQTMNTELDAVEGMQFDRGFVSAYMVTDVDKMEAVLNDPYI
                     LITDKKISNIQELLPVLEQIVQQGKKLLIIAEDVEGEALSTLVVNKLRGTFDVVAVKA
                     PGFGDRRKEMLQDIAILTGAQVISEELGYDLKEADLSMLGRASSVKVTKESTTIVDGS
                     GDKKAIEDRVTQIKHQVEQTTSDFDREKLMERLAKLAGGVAVVKVGAATEVELKERKL
                     RIEDALNATRAAVEEGIVAGGGTAFVSVIPAIGTLIESLEGEVKLGAQIVKKALEEPL
                     RQIAINAGLEGAVIVQNVVNSEAETGFDALNEKYVNMIEAGIVDPTKVSRSALQNAAS
                     IASTFLTTEAAVADLPEKEDVGMPGMGGGMPGMM"
     gene            31008..31748
                     /gene="larB"
                     /locus_tag="PC512_001926"
     CDS             31008..31748
                     /gene="larB"
                     /locus_tag="PC512_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel pincer cofactor biosynthesis protein
                     LarB"
                     /protein_id="HDF2441668.1"
                     /translation="MDLRKLLEEVKNENIDIDFALEKLKDLPYEDLGYANIDHHRELR
                     NGYPEVIYCEGKSDEHILGIIDKMNQKSSNILGTRCRKETFLKIKEIYNHAEYEEASK
                     ILKIQNHDIENIGKGKIVIATGGTSDIPVADEAYHTAKFLGNDVDRIYDVGVAGIHRL
                     LNKRHKIDSARVIVAVAGMEGALASVIGGLVDVPVIAVPTSVGYGANFGGLAALLAML
                     NSCASGISVVNIDNGFGAGYLASMINKL"
     gene            31832..32566
                     /gene="larC"
                     /locus_tag="PC512_001927"
     CDS             31832..32566
                     /gene="larC"
                     /locus_tag="PC512_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel pincer cofactor biosynthesis protein
                     LarC"
                     /protein_id="HDF2441669.1"
                     /translation="MSEKILYFDIISGISGDMTLASLLNLGVPKEIFLEEIHKLRMSD
                     EFNINISSKTENGIVGTKVEVITKEKHTHRNLVDIFEVIDKSTLNENVKSKAKKIFMV
                     IGEAEAKVHGTTIDKIHFHEVGAIDSIVDIVGASILVDLLCVDKVCASTVSVGSGFVK
                     CEHGIIPIPAPATIEILKGVPIKLNNVNGECTTPTGAAIIKVLCDEFVDELEFSPKQI
                     GYGIGHKKFEVPNILRTVLGEKKKKN"
     gene            32596..33015
                     /locus_tag="PC512_001928"
     CDS             32596..33015
                     /locus_tag="PC512_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF111 family protein"
                     /protein_id="HDF2441670.1"
                     /translation="MSSEIYSYLYEKILDEKALDIYTESIYMKKNRPATKVSILCNES
                     DLEKFIKILLLETSTFGVRYNAYNREILERKFVKLDTKYGVVTVKLGYYKGKLVKATP
                     EYNECKTIAKNEDIPIKKVFADINFRIKEEFSENLLT"
     regulatory      33075..33176
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            33397..34932
                     /gene="guaA"
                     /locus_tag="PC512_001929"
     CDS             33397..34932
                     /gene="guaA"
                     /locus_tag="PC512_001929"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HDF2441671.1"
                     /translation="MKHELVLVIDFGGQYNQLIARRVRENNVYCEILPCTASIERIKE
                     KNPKGIIFTGGPNSAYLEDSPTISKEIFELGVPILGICYGIQIMSHVLGGVVRKGNKQ
                     EKEYGKTAITYGKSSLFEGITTNSVWMSHTDLIEKVPEGFTIVANTNDCPVAAMENVE
                     RNLYGVQFHPEVEHCLEGDKILTNFLYNICKVKGDWTTDSFIEDKIKELKEKIGDKKA
                     LCALSGGVDSSVAAVLIHKAIGDNLTCIFVDHGLLRKNEGNDVERIFREKFDINLIRV
                     NAEDRFLSKLKGVSEPEAKRKIIGEEFIRVFEEESNKLGKMDFLVQGTIYPDVIESGH
                     GNAATIKSHHNVGGIPEDVDFQEIVEPLRELFKDEVRKIGLELGIEEGLIFRHPFPGP
                     GLGIRVIGDVTKEKCDILREADAVYMDELRKAGLYREIWQAFATLPDVKTVGVMGDER
                     TYAYLVGLRAVTSSDGMTSDWYKMPYDVLERISNRIINEVDGVNRVVYDITSKPPGTI
                     EWE"
     gene            complement(35009..36055)
                     /locus_tag="PC512_001930"
     CDS             complement(35009..36055)
                     /locus_tag="PC512_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003460085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDF2441672.1"
                     /translation="MPAYKDEQRKSWYASFYFTDFDGDRKKKIKRGFKTKKEALEFER
                     EFLNKSKMSTDMSFESLIEEYMHDMSSRLKLSTLETKKYLINFRILPFFKSLKINEIT
                     ATHIRRWQNELLKSDYSQTYIKTINNQLVAVLNYAVKYYNLPSNPAHLAGSIGKKNAD
                     EMNFWTLEEFKKFIEFEKKSEPRLAFEILFWTGLRLGELLALTPKDIFENKISVEKSY
                     IRLNGEDIVSSPKTPKSKRVVPIPHFLYNNIKDYLSKLYDLKDNERIFKFAKSYLSKE
                     LDRCCKLSNVKRIRVHDLRHSHASLLVNMDVNILTIAERLGHEKVETTWNTYSHLYPN
                     KQLEVAQKLDNLNI"
     gene            complement(36132..36347)
                     /locus_tag="PC512_001931"
     CDS             complement(36132..36347)
                     /locus_tag="PC512_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2441673.1"
                     /translation="MLKKLRKKKRMTQLELAEKMRRNRSYISKLENQEYKDIGISTIL
                     DLSIALEEDFLELCKYYKLQEIKRRGK"
     gene            complement(36781..37182)
                     /locus_tag="PC512_001932"
     CDS             complement(36781..37182)
                     /locus_tag="PC512_001932"
                     /inference="COORDINATES: protein motif:HMM:NF013540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2441674.1"
                     /translation="MQTLAEIIKEYRSEHNLSLREFSNLCGVSHTYIDKIEKNRDPRN
                     GKAVEPTLDMLEKMSFGLNLTLKELLTKLGKIQPNTQQDDELLKKVNSKEDNEVNELI
                     NRLASLDSDDKNAIKKMIDNAYYKAVNTKKE"
     gene            37347..37559
                     /locus_tag="PC512_001933"
     CDS             37347..37559
                     /locus_tag="PC512_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019161272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2441675.1"
                     /translation="MKNNLQYIRKESRISQKKFADKIGISRPYLSRIENGKVNPSLEI
                     AHKISLETGKTINEIFFDFTVNHSKL"
     gene            complement(37854..38072)
                     /locus_tag="PC512_001934"
     CDS             complement(37854..38072)
                     /locus_tag="PC512_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2441676.1"
                     /translation="MTKFKDNIKLVRKQMNMTQKQFASLFGISERAYQYYESGSREPN
                     IETLILISNKLNVSTDFLLGLSPNQNRN"
     gene            38191..38379
                     /locus_tag="PC512_001935"
     CDS             38191..38379
                     /locus_tag="PC512_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2441677.1"
                     /translation="MNNNLKLQREKVGLTQLEVAQKAKITERSYQYYEAGERLPNIRT
                     ALKIARILNTNCEKLFNE"
     gene            38421..>38956
                     /locus_tag="PC512_001936"
     CDS             38421..>38956
                     /locus_tag="PC512_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HDF2441678.1"
                     /translation="MNNLQLNNKNTITTLEIADMLEINHWEVLRKLEGTEKTKGIIDI
                     LNDNNFVVVDYFIKSAYLDLKNENRKCYNVTKLGCDFLANKFTGEKGIIFTARYVKRF
                     NKMEQELKEQQPKLPTTYKEALQQLLIEVEEKEQLQLENQEKDKVIQLQQPKVLFADS
                     VASSDNSILVGELAKLLR"
BASE COUNT        15197 a         4327 c         6666 g        12766 t
ORIGIN      
        1 gtagaatgga tttgtcaagt ttaatttagt tgtaattcta tcttttatta aaaataacat
       61 aaattaaaac atataaataa aatattttat acaatatatt gtaaaggagg taactttgat
      121 gaaagcagaa aaaacaagta tatatccaat tattaaaaat aatttaaaca aaatatcaat
      181 tgttgaatat aaaaagggtc aaagatttgt agcatcagat aaagacttac aagaagtgtt
      241 ctttataata gagggagttg cattagtgga gtgtactact agaggaggaa ataaatttct
      301 tgttgacatt gtacctgaaa atgaatttat aggcaaaatt agttacatat atgaacataa
      361 tttgaaatgt gatatatttg caaagactaa tataaaatta tttcgatttg aaaaaaatgt
      421 atttgaagag ttttatctca aaccagattt tattgcacta tttcacagaa aatgtacaag
      481 aagaatatat gaattatata aaaccagaat ggtaagagaa ctattttctt gcacagaagt
      541 tattgcctat tgtatatcaa ataaacaaga aaataatgtc tgcaatataa aagctattcg
      601 taatttcagt gaaatctatt caattagtag aaaaagtaga taccattctc tgctaaagtt
      661 aactgaaaag gagatagtaa aaaaaatggg taatacatat gaaattttaa actatgatga
      721 attacataaa ttggcatttg aagtaaaaga atttttggaa gatgagtaaa aattgttact
      781 taatcaaaat aaagtataat aatttctgta aaaaatagaa atagtctcac tgaaaatcaa
      841 aaatacttta gttattttca atgagactgt ttagaaatat tgtatactta taatgtatag
      901 tataattatt aatcaatttc ctttactata ttaatagccc attttttaga taatgctcta
      961 ggaacaccaa atataaactt aaccacttct tcactataag tgagcaaaac gagtacaaat
     1021 ataggtgcac ctttaaatgc agctataaaa gttagaggaa tagaagctaa ccacatacat
     1081 cctaattcta aaaatagagc atatttagta tctcctccac ttcttaaaat accaattata
     1141 accaatgtat taaaagattt aagagccatt agtattccca ttataaagaa tatcttagtt
     1201 atatcagaag ctaagctatc agaaacacta aacattttta ataataatgg tatatttaaa
     1261 attaaaataa ttccaagtat taaaccagct gaaaatacaa gtatagaaaa ctttttagca
     1321 tattcaatgg ctcttttaat atggtcagct ccaagttcat ttccaagcat aatagatgca
     1381 ccagatgcaa tacatacagc tgtcattatg aagaaattac ctgtactggt tgctatctgg
     1441 ctagctgcta tagcagaagt accagctctt gcatatgcaa cagaatacag gacagttcca
     1501 attgcccata cagagtcatt tacaaatata ggaaagcttt ttgatgaaaa agattttata
     1561 aaaattttat caatagcttt tagatttttt agaccaaact ttaatatata gtctttttta
     1621 taaaggtaaa cataagtaat cattaaaatt aattcacata ttctagcaat aacagtagct
     1681 agagcagcac cttttacacc caatgcagga agaccgaagt taccaaatat aaatccataa
     1741 tttaaaataa catttgttac aagtgcaaat gcactacaaa tcatacctaa cttaggattt
     1801 ctaacacctc ttgaaccagt actaaataca gtacttacag caattaatgg ataactaaat
     1861 actgcaatac taaagtaatc tatacaaagt tttaccacct cagaatcata cgaaaatatg
     1921 tgtataattg gctttggtgt tagtaaagca ggaataacaa atacaaaact taaaacaatt
     1981 gccaatacac aagtaagacc tgtgactttt cttatattac tcacatcctt ctttccataa
     2041 aactgtgaaa taaaaactcc agcacctcct gtgataccag ataaggacat attaaaaaga
     2101 aagaaaaatt ggtttgcaac tccaactgaa gctacagatg tttcccccaa actacttatc
     2161 ataattgtat ctattacatt tacagaagta gaaattaagt tctgtatgat aataggtata
     2221 cataaagata gaagtatttt ataaaatctt ttattttcgt cttttaaaga aaatagttct
     2281 tgcaaataat cctctccttt ttacataaat tcttcccact catcatatag agaggcaagg
     2341 ttattttcta aattaatttt ttcttggcta acttctttag ctttatctgg attagagtat
     2401 acttcttctt gacataaaag tatatctaat ttttcaattt caatctctaa cttttcaatt
     2461 tctttttcta tattttgtct ttttattcta tttttctttt ctatttctct ttgttctctc
     2521 tcttttcttt tttcatcttt tatttgagtt ctagtttttt cttctttttc ttctataata
     2581 ctcatctctt ggatttgcct ttttttatct atataataat cataatttcc cagatattca
     2641 gtaattccat tttcatctaa aactaaaatt ttatcaacaa cagtatttag aaagtatcta
     2701 tcatgtgata ttgtaaatat agtcccatca taattagtta aggcctcttc aaggacttcc
     2761 ttagaatcaa tatctaggtg attagtaggc tcatctaata acaataagtt tgcatttgat
     2821 agtataagtt taagtatggc aactctagct ctttctccac cactcaatgt agaaatcttc
     2881 ttaaaaactt cttcatctac aaataaaaat gcccctaaca tatttctcaa agtagtttga
     2941 gtaagatgag tattattttc ccaaatctca tcaattattg tgttatctaa attaagagtt
     3001 ttttgttcct gatggaagta ggaaacatgt acattagttc caaatttaat attgccacta
     3061 agaggttgta gttcattagt tattatttta aataatgtag atttgccaac accatttgca
     3121 cctataagtg caactttttc ccctctatat atatctaaat ccaagtcttt aaaaagtatt
     3181 ctttctccat aacccataga tacatctcta atttgaagaa catcattacc actctggaca
     3241 gaaggcgtaa attgtatacg agcttttttc ctataagctt ctggtttatc taaaacatct
     3301 actttgtcta atgctttttc tttacttctt gcacgcttta ggtgtttttc tctaccataa
     3361 gcttttagtc tttcaattga ttcttcttgc ttttttattt ctttttgttg gtcttcaaat
     3421 ttcttaagct ctagttcttt ttctatttta gataactcaa caaatttaga gtagttacca
     3481 ttatatactt taagcttttt attgtgaact tcaaaaattc tatttacgga ttggtctaag
     3541 aaatatctat catgagatat taacatgaca gtccctttat attgttttaa aaatacttct
     3601 aaccattcta ttgcttcaga gtctaagtgg ttagtaggtt catcaagtaa caatagagtt
     3661 ggtttcttaa gaagtaattt tcctaaaaga actctagttt tttcaccacc agaaagtatg
     3721 cttattggct tatccatatc attgtcacta aatcctaatc cctttagaac tcctttggct
     3781 tcagatttat atccatatcc atttaaatct gaaaataatt ctagtttatg tgaatattca
     3841 tccatgattt tttctataat tggagagttt gtttttgtac tttcttcaga tattttaacc
     3901 tccaattctc ttaaatagga ttccatttct atcaaatttt taaaaacttc tagtacttct
     3961 tccaaaatag tattatccga ataaaaattg gtattttgtt ctaaatatcc gatttcacaa
     4021 tctttagaag tgtaaatatc tccactatca tatccataaa ttcctgaaat tattttaaat
     4081 aaagtagttt ttccagtacc attaacaccg attataccaa ttttatcgcc ttcatttact
     4141 gtaaaactaa tattttctaa tatagaatct ataccaaaac ttttatttaa gttattacat
     4201 gacaaaacaa tcataaattt ctacctcctt gaactatcta aaattataat gttttgatat
     4261 aatataatca aggttatatg tattagtttt gaaaaagaaa tattttattg tgaatcaaac
     4321 aaaaaagagg acacttttag gaggtgaaga tgttgggaaa taaaaatata tcaatggcag
     4381 ttataagaag gctcccaaaa tatcatagat atcttggaga cttattagat agggatatac
     4441 aaagaatatc ttctaaagaa ttgagtgata taatagggtt taccgcttct caaataagac
     4501 aagatttaaa caactttggt ggatttggac aacaaggata tggttataat gtagaagctc
     4561 ttcatactga gataggtaaa attcttgggt tggatcgacc atacaacgca gttcttgtag
     4621 gagcaggtaa cttaggacaa gctatagcca attatgcagg atttagaaaa gctggattcg
     4681 agataaaagc tttatttgat gcaaatccta gaatgatagg tttaaagata agagagtttg
     4741 aagtattaga ttcagatact ttagaagact ttataaaaaa caataatata gatattgctg
     4801 tattatgtat acctaaaaat ggagcacaag aagttattaa tagagttgta aaagctggaa
     4861 tcaaaggtgt atggaatttt gcacctttag atttagaagt tccgaaaggt gttatagttg
     4921 aaaatgtaaa cttaacagaa agtttattta ccttatcgta tttaatgaaa gaaggaaagt
     4981 agacaactta aacatattaa taatgagcag ttgtaaagag tattgagaaa gtcagaagat
     5041 ttaatattaa atcctctggc tttttgaaat attaggataa aaatttaaat aatgtatgga
     5101 aataaacaat attaaggaga gtggtttttg tggaggaatt atggaaaaag gcaattgaat
     5161 ttcatggtca tgaatgtcca gggttagcta taggatttaa agcagcactt gcagcaaaaa
     5221 aatatttagg atgtaaacag tcaggagatg aggaaattgt atgtatttct gaaaatgatg
     5281 cttgtggaat agatggtata caagtagtgc taagttgcac aatgggtaag ggaaatttac
     5341 tacttaggat gactggaaaa tcagtatatc atttctttaa tagagaaaat ggaaaatcta
     5401 taaggatata tgtaaagtca aaaccatttg agatggatag agaaggatac aaaagatatt
     5461 tattagaaag tgattttgaa gaaatatttg agattacaga tactaagtta agacttcctg
     5521 aaaaagcaag aatatttaaa tcccttaaat gtgaagtgtg tggtgaattt gcatctgagc
     5581 aatatataag gattgaagaa ggaaagaaag tatgtcttga ttgttttgat aaatatgaaa
     5641 gattttatga agagtattaa aattataaat tagattaaag ttaaaagtat tagatatgtg
     5701 ctaacagtat tttaagatga attaggtagc aacataataa agtatataaa taatattaat
     5761 tgaatcatac ataattaaaa agaggctgat tagtatttat aaaataaaat cagtctcttt
     5821 atgaataacg aattattatt ctggttgagg tgcatctaca ggacaagctc ctgcacaaga
     5881 accacagtct atacaagaac cagcatctat aacatatgcg tcgtctccag ctgatataca
     5941 gctaacaggg cattcagcct cacaagcacc acagcttata caagcgtcag taattttata
     6001 tgccattttg aaatcctccc ttttatatgt attgtaattc aataacatta taacaaatat
     6061 tattgaatat aacaattaaa ttaattctac aacaaaaact ttattatgat attcttgttt
     6121 taaagtttta caataaagtt taatctgctt atatttttat ttattttaaa gaagtttatt
     6181 ttaaaaataa aattaaattt aaaaagttat gtattgatta tatttaaaaa tgttatactc
     6241 taaaaaagta tattttattt aaaaatttat taatacaaag gagatttact atgaaaaata
     6301 aattagttta catatgtatt atgagtctat tgctatttgt agtaggatgt tctaataatc
     6361 caaataagga aagtaccatt aaaaaagact ctaagaataa ccaaagccaa gttaaagaag
     6421 aaaaaagaga acctgtgaaa aaagatataa ctataagttt cgctggtgat gtaactatgg
     6481 ggaactataa aggttcatca tattatggca gttttgacca tgaatttaaa agacaaggag
     6541 aagattacaa ttattttctt aaaaatgtaa aacctgtatt tgaaaaagat gacttaacag
     6601 tggttaattt agaaggtcca cttactacag cgtcaaatgc aaaagaaaaa aaatttgcat
     6661 ttaaaggaaa gcctggatat gtaaatattt taaaatctgg aagtgtagag gcagtaagta
     6721 ttgcaaataa tcattcagaa gattattttg aagaaggaat gaaagataca cagtttatat
     6781 tggacgagaa taaaataaat tattttggat tagggaaaga tgctgttgta gatgtcaaag
     6841 gaattaaagt gggtctatta gggtataatg gattatcaac tgaatataat gaaaaaaatt
     6901 taaaacaaat ggaagatgat attaagtcct taaaaaagaa atcggatgtt gttgtagtgt
     6961 actttcattg ggggatagaa ttagattatt atccagataa aaaacaaaaa gattttgctc
     7021 attatgctat agacaaggga gcagatttag ttatggggtc tcacccacat gtgattcaag
     7081 gaatagaaaa gtataaaaat aagtatatag cttatagtct agggaatttt tgctttggag
     7141 gaaataagaa tccttctgat acagatagtt atatatatca acaaaccttt actttttcag
     7201 ataataaatt aacttcaatt aaagagccaa atataatacc aacttcaata acatctagta
     7261 actccagaaa taattatcaa ccaaaaatat tggatggaag tgagaaggat agagttttaa
     7321 ataaacttga aaaaataagc aaagatttaa ataaataaaa tgtaaaaaaa aataaatata
     7381 tatatttatt ttaataattt atattttgtt tagggtatgg taaatcgtgg tattaaataa
     7441 gtagatttta atagttaaat tatagtcaat tataataaag ctatttaatc tactttttta
     7501 atataaaaat ataaggggga atttgtaatg gcttgtaaca cttgtaaaat gtgcgaaagt
     7561 gcagacaaga aattagaaag ttttgtagct tcaaaggatg ttgaaacagc atttcataga
     7621 acagaagatc agaaagttaa gtgtggtttt ggacttcagg gggtttgttg tagactctgt
     7681 tcaaatggac catgtagagt aactcctaaa tcaccaagag gtatatgtgg agcagatgca
     7741 gacactatag tagcaagaaa ctttttaaga gcagtagcat caggagcagc ttgttattta
     7801 catgtggtag aaaatacagc taagaattta aaaaatgttg gaataactaa aggtgttgtt
     7861 aaaggagaaa aaacattaaa tcaattagca gagatgtttg gaatagaaag tgatgaaaag
     7921 tatgataaat gtataaaggt tgcagacaaa gttatcaacg atttgtataa atcaagagat
     7981 gataaaatgg aattagtaga aaaaatagct tatgcaccta gagtgaaaaa gtggaaagag
     8041 ttaggtataa tgcctggtgg tgcaaagtca gaagtttttg atgcaatagt aaaatcatca
     8101 acaaatttaa acagtgaccc agtagacatg ctagttaatt gtttgaactt aggtatatca
     8161 acaggattat atggtcttac actaactaat cttttaaatg atgttatgtt gggagaacca
     8221 gttataagaa tggctcctgt aggatttaat gtaatagacc cagactacat aaatataatg
     8281 ataacaggtc atcaacattc aacatttgca aatttccaag atagattaaa agatgaagat
     8341 gttataaaat tagctcaatc tgttggcgca aaaggattta agttagtagg atgtacatgt
     8401 gttggtcaag atttacaatt aagaggagaa cattatcaag aagtatttgc tggacatgca
     8461 ggtaacaatt ttacaagtga ggctgtttta tcaactggag caatagatat agttctttca
     8521 gaatttaact gtactatacc agggcttgaa ccaatagcag ataaatataa agtaaaaatg
     8581 gtttgtttag atgatgttgc taaaaaagcg aatgcagaat gcataggttt agacagaagt
     8641 aaattagatg aacttagtaa cactttaata gaaaaagcat tggagtctta taaggagaga
     8701 agaggaagta ttgaaataga tataccaaaa gaccatggat ttgaacaatc tttgactggt
     8761 gtaagtgaaa agaacttgaa agcgttttta ggagattcat ggaaacctct tattaattta
     8821 attgcagaag gaaaaattaa aggtgttgca gctgttgtag gatgttcaaa tatgacagca
     8881 ggaggacatg atgtaaatac tgttgaactt actaaagaat tgattaaaaa agatataata
     8941 gtactatctg caggatgttc tactggagga ttagaaaatg ttggtcttat gtcacctgga
     9001 gcagaagaat tggcaggaga aaacttaaaa gaagtatgta agactttagg aataccacca
     9061 gtattaaact ttggaccatg tctagctata ggaagactag aaatagtagc aacagaatta
     9121 gcagctgaac ttggaattga cctaccacaa ttaccattag tgctttcagc tccacaatgg
     9181 ttggaagaac aagcattagc tgatggagct tttggtcttg cccttggctt acctcttcat
     9241 ttagctttac ctccatttat aacaggagga aaattggtaa cagaagtatt aacagaaaaa
     9301 ttaaaagact taacaggagg acatgttata gtgaatccag accctaaatc ttcagctaat
     9361 caattagaag aaataataat agatagaaga aaaaatttag ggttaaagga tgtggaatgc
     9421 aatgcataga atttttataa ataaagattt atgtacagga tgtaagagct gtgtactagc
     9481 atgtatgcta aaacacaata aagattatga catgtacact cttgatttag aaaatataga
     9541 taatgatagt agagggcata tagaattaga tagtagacat aataatccag ttccaattct
     9601 ttgtagacac tgtgatgaac ctgaatgtgt attagcatgt atgagtggtg caatgcataa
     9661 agatagtgaa agtggaatcg tttcatatga tgaagagaaa tgtggttcat gttatatgtg
     9721 tgtaatgtct tgtccatatg gattattaaa gccagatgat agaagcaagc agaacatact
     9781 taaatgtgat ttatgtaaag atgaggagta tcctagatgt gtagctaatt gcccaagtgg
     9841 agcaattgaa ttacagaagg aggaaaatga tgaattatgt agtgttaggg gctagtgcag
     9901 ctggtataaa tgcagtaaaa acattaagag aattagataa agattcaaat atagtagtaa
     9961 tttctaaaga tgaaaacgta tattcaagat gtatgttgca tcacgttata tctgaacaca
    10021 gaactttaaa acaaataaat tttgttgatg aagattttat ggagcaaaat aatgtaaaat
    10081 ggattgcagg taagactgtt aaaggtatag acataaataa aaaggtagtt cagacagaag
    10141 acattactgt aaattatgat aaacttttaa tagctacagg tgcatcttct gctattcctc
    10201 ctataaaaaa tttaagagat ggaaattttg tatattctgt gagaaacata gatgatattt
    10261 ataaaataaa agaaaaagca caaaattcta aaaatgtagt tataataggt gctggtttag
    10321 ttggtataga tgcattagtg ggattattta aatatgagca gttaaatatt tctgtagctt
    10381 ttatggaaaa gtacatttta gatagacaat tggatgaata tacagcatca gtgtatgaaa
    10441 ataagttcaa agaaaaaggt gtaaaatttt acccaagtgc atcaatacaa gaaattgtat
    10501 tggataacag taaaaatgtt acaggtgttg cattttcaaa tggtgaagtt ttagatgcag
    10561 acatggtaat tgtagctaca ggggttaaac caaatgctga ctttttagat ggaacaggaa
    10621 tagaatatga tagaggtata ataatagatg atatgtgcca aacaacacaa aaagacatat
    10681 atgcagcagg agatgttgta ggtaaaaatg ctatttggcc tctggcagta aagcaaggaa
    10741 ttgtagctgc ctataatatg gttggaaaag ataagaagat agaagatgaa tttgctttta
    10801 aaaatagtat gaatttcatg gatataccaa ctatttctat aggaatgaat acacctgtag
    10861 atgatagcta taaagtatta accagacatg gaattaatga ttataaaaag tttgttttta
    10921 aagataatgt aatctatgga gcagttatac aaggagatat ttcatatgta ggtgtattaa
    10981 cttatttaat aaaaaataaa gttgaaatat atgatttaga aaataggata tttgatatat
    11041 gttatgcaga cttttttaat ataaaagaaa atggagaatt ttgttatagt gtatagtata
    11101 tacgtggagt aaggtttata aatacagtaa atcaataaat agagttattc taaaataaga
    11161 aaaatgacaa atcttattta gaaatagctc tattttttgt aattaaattt aaattatatt
    11221 caatttgtaa aatattattt tgaacaatta tacatatact ctctagttag aggtaaatca
    11281 ttttttatac ctttagtgaa aagtatttga tgtatatcta taataccagt gttgaaagca
    11341 gcagcacaag aacaaaggta taaatcccac attcttataa acttatcatc aaacatttct
    11401 ttaatctttg gaagattctc agagaaattt ttttgccagt atagtaaggt ttttacataa
    11461 tgtaatctta aactttctac gtctatagta tgatatttgt aatcactaca aatatgtatc
    11521 atttctctta ggctaggaat aactcctcct gggaaaatat atttttttat ccaagggtct
    11581 ccataagatt cctgcaatcc acttatatag tgaagtaaaa acaatccacc atcttttaaa
    11641 acagcattta cgtttttaat gaaaagttca tagttttctc taccaacatg ttcaagcatc
    11701 ccaacgctta caactctatc aaacataagg tctgattttt ttaattctct atagtccata
    11761 agtcttacct caagatagtc ttgaaggttc tcttctttaa ttcttgcgtt aaattcctta
    11821 aattgctctt cgctaagtgt aattccaacg ccgtgaattt tatatttttt tgcagcttct
    11881 attagtaaaa atccccaacc acaaccaata tcgagaaggc tcataccttc ctctaaattt
    11941 agtttagtta atatgtggtg aactttattg acttgagcat cataaagagt atcattatca
    12001 tttctaaagt atgcacaaga ataactaagt gtcttatcta accataagct ataaaaatcg
    12061 ttgccaatgt catagtgggc atgtatttct ttcttttgat gtctcattga atttgatgag
    12121 tgcaatagat gttttacagc tgaattatca atattgaatt tgtctatttg ttttaaaagt
    12181 agatttaaag ttaagaataa atctccctca acttcaatgt ctctatttat gtaggcttct
    12241 ccaagtgcta aagatgtact ttttaatagt tcagacttgc taatatcatt atttactata
    12301 actttgaact gaggggagcc ctctccaatt agaaattctt cctcatcttt aagcctaact
    12361 agaaatggtg tttcaccaaa tttctctaaa tagtctttta aaaaattttt tgtaatattc
    12421 atattaccag ctccttctaa tgtaaatcca gtaagtttcc ctgcttaaaa tatattatag
    12481 tccttttttt aaaaaagtaa aattttttca ataaattttt tatttaaagg aaatttattt
    12541 tttgtaaaga aatttcatgt tgtagtatat tttttgctta taaattttgg tactggatat
    12601 aatattaaac tgttaatgat ataataaatt taatctataa agtaaataaa attttgtaat
    12661 aaatagttaa agctatttta taaggagata tatgatggaa gtatatgctt tggttgggtc
    12721 aagtggcaca gggaagagct ttaaggcttt agagttcgca tatgaaaatg atatagaata
    12781 tataattgat gatgggattt taatatacaa aaacaaggtt ttagctggga tatcggcaaa
    12841 acaagcaaat actactatag aagcagttaa aagggctatt ttttataatc tggagcatag
    12901 acaagaagtt agagaagcaa ttaaaaaaga aaatataaga aaaattctta ttattgggac
    12961 atcaaaaaaa atggttaatc aaattgtaga gagattgtca attggaaggg tttgcaagtt
    13021 tataaatata caagatataa gtactaaata tgaaatagaa atagcaaaac aagctagaaa
    13081 agaaggaaat catgtaattc ctgttccagc agttgagata aaaagtatgg caagtggtct
    13141 tagtataaat tctttgaaga gactttttag aaaaggaaat aataggaata tggtagtttt
    13201 agaaaaaaca attataagac caacttttag ttatatagga aagttttata ttagtgctga
    13261 tgtaattaaa cagattattg aatatgaagt atacaacttt ggaagcattg atagaataaa
    13321 taaaatcaat atagagaatt gcaataattt tatgaatatt tttgtaagta taaatatcaa
    13381 tgatttagaa actataaaaa aaattgaaga catacaacag acaataaaaa agtctattga
    13441 gaaaatgact ttagttaatg tacaaaaaat agatattaac attcataaaa ttaaaaaaat
    13501 aaacttcctc caatgttaaa aaataaactg agaaaatgat atactaattt gcaataaagt
    13561 gtgctataat taaactgtaa atttaggaaa tggttttttc taaatggagt atacataatt
    13621 ataacgtatt tataaggggg ctttcaaatg tcaggaaaag atgtaaatgt cttcgagatg
    13681 gcgcaatctc aagtaaaaaa tgcatgtgat aaattaggta tggaaccagc agtttatgaa
    13741 ttattaaaag aacctatgag agttatagag gtttcaattc cagtaaaaat ggatgatggt
    13801 tctataaaaa cttttaaagg atttagatca caacataatg atgcagtagg gccaacaaaa
    13861 ggtggaataa gattccatca aaatgtttca agagacgaag taaaagcttt atctatatgg
    13921 atgactttca agtgttctgt aacaggtata ccatatggtg gaggtaaagg tggaataata
    13981 gtagatccat caactttatc tcaaggtgaa ttagaaagat taagtagagg atacatagat
    14041 ggaatatata aattaatagg tgagaaagtt gacgttcctg caccagacgt aaatactaat
    14101 ggtcaaataa tgtcttggat ggttgatgag tacaataaat taactggaca aagttctata
    14161 ggtgttataa ctggtaagcc agttgaattt ggtggttctt taggaagaac agctgctact
    14221 ggatttggtg ttgctgttac tgcaagagaa gctgctgcta aattaggaat agatatgaaa
    14281 aaagctaaaa tagctgttca aggtatagga aacgttggtt cttatacagt tcttaactgt
    14341 gaaaaacttg gtggtactgt tgtagctatg gctgaatggt gtaaatcaga aggttcttat
    14401 gctatataca atgaaaatgg tttagatggt caagctatgt tagattatat gaaagaacat
    14461 ggtaacttat taaacttccc aggagctaag agaatatctt tagaagagtt ctgggcttca
    14521 gatgttgata tagtaatacc agctgcatta gaaaactcta taactaaaga agttgctgaa
    14581 tctataaaag ctaaattagt ttgtgaggct gctaatggac caactactcc agaggctgat
    14641 gaagtatttg ctgaaagagg aatagttctt actccagata tattaactaa tgctggtgga
    14701 gttacagttt cttacttcga gtgggtacaa aacttatatg gatactactg gtcagaagaa
    14761 gaagtagagc aaaaagaaga aatagctatg gttaaagcat ttgaatctat ttggaaaatc
    14821 aaagaagagt acaatgttac aatgagagaa gctgcttaca tgcattcaat taagaaagtt
    14881 gctgaagcta tgaaattaag aggatggtac taagatttac tcttaataaa taataggata
    14941 taattattta agatataaag gggctgtaca tagtacagcc cttaaattat gtggcttaca
    15001 atgaagtaag ctatttttgt tttaacttat aaataacttg ataaattatg taatttagaa
    15061 tgtatttttt accaccacat gattacaaat tagaggagtt agattgaatt tttagacatg
    15121 aacttatgca ttttaaaagc aaagacctta atttaaagta tctagtatta tttttaaaaa
    15181 tagtatattg gtttaatcca tttatatgta taatggaaaa atatatggat ttggattgtg
    15241 aactttattg tgatgagaga gttttaaaaa attgtactgt acaacaaaag caagaatatg
    15301 ctctaactat tgtaaattca atgaaaagaa gtacaaattt ttcaaataaa tttgtagctg
    15361 gattaaataa acaatctgat attagaaaaa gagtaataaa catgttcagt gaaaaacata
    15421 aaaatggtat cttaagggct ttgattataa gcttgttttc ttctattaca ttttttaaat
    15481 tcgattcaac tagtattatt gaagagaatg atttcttaga gaggtcaaga tatacgtttg
    15541 aaggaaggca agaagacatg tttgtaacaa tagattttat atatgcagat gtacctataa
    15601 aacttagaaa agagcatgaa gaaaactgta gagtcaatgg aatagtacca aaagattcag
    15661 attcaataga aattattcct agattttata aagattgtat ggatttaaaa aaataagtta
    15721 gacttaatat tgatgttgat attatgaatt ttttatattt aagcaattga aaattttatt
    15781 atagattcaa ttttatatgt gtttaagtat gaaatttata gatagttgaa ataattaaat
    15841 atgattgatg cataggaatc attactaagc tataattaat tataggggag tttaaataaa
    15901 ttatgagtta cacaatcata aaatgataaa aatagttatc tgttacaaaa aatgtatctt
    15961 tttaattaat aaagataata tgaaaactta aaaggcaaat aaacttaaat ataaaatact
    16021 cttaaataag ataggagaaa aatgtatgtc taactttatt ctaaatggga tttttagaac
    16081 agttatagta agtagtctaa gcattcttct gatattgatt ttcaagaaaa atgtatttaa
    16141 aagatttagc aaaaaattta attattatat atggatgata gttgttatta aattattttt
    16201 accatttaca tattatactt ttacaataaa tatcttgaga agtaaaaaac acattaatat
    16261 taataacata aatttagagg gatttaataa tgtttcaact ataagtaata atattatatt
    16321 gtacacttgg attataactg tagtagtgta tttaatttac actatattta aatatataaa
    16381 acttaaaaat ttaataaatg acttatctta tgatgttgat gatagagaga ttgtaaatct
    16441 ttataaaaat atattagaag aatttaatat aacaaaagat ataaaactca aatactctta
    16501 tgaagttgaa acaccagcat tttttaattc atgtgtactt ttgccaccac atgagtataa
    16561 attgaaagag ttagactgga tttttagaca tgagcttatg cattttaaga gtagggacct
    16621 ttatttaaaa tatgtaatcc tatttttaaa aacagtatat tggtttaatc catttatata
    16681 tataatggat aaacatatag atttagattg tgaactttat tgtgatgaaa gagttttaaa
    16741 aaatcgaaat tcagaggaaa aaaaggatta tgctttaaca attctaaatg caatgagaaa
    16801 aggttcaaat acttcaaata aatttatagc tggacttcat aagcaatctg atattaaaaa
    16861 gagagttatg aatatgttta atgaaaagta caagaatggt atattaatgg cattaacttt
    16921 atgtttatta tcttctatta cttttttgaa ggttaattca actagtattg ttaatcttaa
    16981 tgtattacct aaaggatttg aagacttacg aactgttagc agtatacgtt tttcagttat
    17041 aggatttaca tatgcagatg ctcctaaaaa tatgagggaa gaatataaaa taaattgtga
    17101 atcattaggt ttgataccta aagactctga taaaatagaa gttggtatag aatattatga
    17161 cagtctattg aatgattaaa taaatattat tttaacagat attaattata aagttttgaa
    17221 tagtaatttg ttgagaaata aatatatcct tataaaaata gatacttata taccaagaat
    17281 aaaaaatagt caagatagta cacaaggata tacttataaa gaacttaaat aagtgaaata
    17341 aattattaat tataaggttt ataattttaa aaaattagat aaattcaggt gtaaaatact
    17401 ataaaacaca attcggaaaa gtgtatgttg aacttcattt aaaatggaat ttcaaagttg
    17461 ctatagtaag tagtttaagc attcttctta tattaatctt tgagaataat gtatttaaaa
    17521 aagttagtaa aaaatttaac tattgtatat taatgatagt tgctattgat atattatcta
    17581 aaaaaattaa gtatgaaaag attactgcta ggacaatctt ttcatactta atttttaata
    17641 tttatattat ccaaaatttt catcttttta acttagaatt tgagaatcac tattaggaaa
    17701 taggctttga tttatgtagg gttaaaaatt tcacagaata tctaacttta tactaaatcc
    17761 atcaaaaaat atacgccata caaaagcgca taaaaaaaca cataaaacaa tatttatgcg
    17821 cactttaacc tcgaatggta caaaattctt tacttttaca gacccatatt atataattaa
    17881 gtaaataatg tatatttagg tgacatattg gataagctaa tttatttatt ttattaatat
    17941 aataatacta taaaagttat ataaagtggt ttacaaaaaa gttacagata gagcttttat
    18001 taatgtattg tgtattagta ttttatcctt aggtacactt cacctacaaa atagaatcat
    18061 aagataatta tgggaaaatt ttaggaggtt tatcgtgaag aaaaagatat taataccagt
    18121 atttgcatca gttatggcat tatcagtaag ttcaattgta aatgcagatg aagtaaatga
    18181 ttcatctcaa aataaggatg ataaaacaaa tactgaatta aatttaggtg aatataaaga
    18241 agtaaaatat aaagttgcaa aaataaaaga tggagtagct ataaagataa gagaagaagg
    18301 tcaagttcaa aacatagctt attctggaga tgaatttacg gttttaggaa ctcaaggaga
    18361 atgggttaag gttaaagttg aagatggcga aggttggtta gctactagat atgtagatat
    18421 atctgaaggt gtaggatata ctaacgctga taaagtaaac ttaagaaaag ataagagtga
    18481 aagttcagaa gtaattgaag agctggaaaa aggaagttct ttattggttt tggaagataa
    18541 tggagattgg ttaaaagtta aagatgggga aacagaagga tatgtaaaat catcttatat
    18601 atctgataaa gctcctgtaa tagaagagcc acaagtaaac ccaagtattg accaaaatgt
    18661 agattctaca aataataatc aacaaaacaa tgcaaatact aatcaacaaa ataataattc
    18721 aaatgtgcca acagctaact ctaatgcagt tcaagctgta cttaacttgg catattctaa
    18781 gcaaggttgt ccatatgttt ggggagcaga aggaccaaac acttttgact gttctggatt
    18841 tacacaatat gtgtatagaa atgcagtagg aaagaatata ccaagaacat ctaaagcaca
    18901 atctaaatat ggacaaactg taagtaaagc aaatttacaa ccaggagatt tagtattctt
    18961 cacaactaat ggttctggtt ctgttagtca tgttggaata tatgtaggtg ggggtaatat
    19021 gatacactca ccatcaacag gaaaaacagt tagtgtaact agtataaatt catcatacta
    19081 tacagcaaga tttgttacag caaaaagaat attataatcg gtttgtaata tgacaaattg
    19141 ataaatacat aaatatatat aaacgctcta tattatattt aatttaatca tggaaacaaa
    19201 ataatgatta tattttaaat gtactataga gcgtttttgt atcactttaa atctaatcaa
    19261 gattcaagtt aatatgactg ttaaatagga gccttttcat atgatgatta tttgtgcaat
    19321 cccttgacag gatagggtaa aggtggtaag ctactaacag tacaaaaata cttttaattt
    19381 tagttcagag aggctaaaaa aggaggacga aagatgttaa aatcaagaaa tttaatccaa
    19441 ccagaagact tttcaataga agaaatagat gaaatattag aattagctca aaagataatt
    19501 gacaatccgt caaaatattc tcgtatatgt gaaggaaaac tattagctac attattttat
    19561 gaaccatcaa caagaacaag attaagcttt gaatctgcta tgaacagatt aggaggacgt
    19621 gtagtaggct tttcagagcc aaattcatcc tctgcatcaa aaggtgaaac tctaggagat
    19681 acaatgagga tagtatctgg ttatgttgat ataatagcta tgagacatcc tcaatcaggt
    19741 gcagcttcag aagcagctag atatacggaa gtgccattta taaatgcagg agatggcaaa
    19801 aaccagcatc caactcaaac acttacagac ttacttacta taaaatcatt aaaaggaact
    19861 ttagaaagcc atacaatagg attatgtggt gatttaaaat atggaagaac tgtgcattct
    19921 ttggttaagg ctatggcaag atataaaaat acaaagtttg tatttatagc acctgaagag
    19981 ttaaaaatgc cagattatat aaaagaagct ataaagggac atgcatatta tgaaactaat
    20041 aatttggatg atgttatagg aagcttggat gttttatata tgactagagt tcaacaagaa
    20101 agatttgaag ataaatcaga gtatgaaaga cttaaaaact attatatttt aaataaagct
    20161 aaattagaaa aggcgtctaa agatatgtta gtaatgcatc cattaccaag agtaaatgag
    20221 atagacatag atgtagatag tgatgataga gctgtatatt ttaaacaagc taaatatgga
    20281 atgtatgtta gaatggcttt aataataaaa cttttaggta taaatgaaga ctaatagtta
    20341 tcatataata gtaaaacaaa ggagattttg ggatgtataa aattctggaa aatatatata
    20401 taggcgaaga tatgtataga atgaaagtaa aaggtaattt tgaaggtaaa atgggacaat
    20461 tctatatgtt aagagcatgg gatacttatc cagtactttc aagacctata agtatacatg
    20521 atatagatga agaagggata acttttcttt ataaagtagt aggagaagga actcaaattt
    20581 tgagtaacct aaaggtaaat gatactataa aattggaagg cccttatggt aatggatatg
    20641 ctaaggttga tggaaaggta gctctagtag gaggaggaat cggtgtagct ccactatatt
    20701 tggttgctaa aaatataaaa aattgtgatg catatcttgg ctttagagaa gatgttatat
    20761 tagaagatga atataaacaa gtatgtaata aagtatatac aacagtagga aatacttttg
    20821 taacagatat aattgatgtt gagaaatatg attatatatt aacatgtggt ccaactccaa
    20881 tgatggaaaa attagttaag atggtagaag gtactaaaac gagaattatg gtatctcttg
    20941 aaaaccatat ggcttgtgga gtaggtgcct gtttagtatg tacgtgtaaa actaatggag
    21001 gaaataaaaa gacttgtaaa gatggtccag tgttctgggg agaggacgtg atttttaatg
    21061 ggtaatttaa gtgtgaaatt tggaagtgta gaatttaaaa atccagtaat aatggcgtct
    21121 ggaacttttg gatttggaaa agaatataat gagatttatg atatacaaaa acttggtggt
    21181 ataagtagca agggtcttac tttaaataaa aaacctggta acaatggtat gagagttcat
    21241 gagacaccat ccggtatgat gaatagtgtt gggcttgaaa accctggagt tcaaggattt
    21301 atagactatg aattaccttt ttttagtaaa ctagacttag tcagaatagc taatgttgga
    21361 ggtgggacat tagaagacta cttattaggg gttcaaatgt taaatgacaa gcctatagac
    21421 attattgaat taaatatatc ttgcccaaat gtcaaagctg gtggaatggc ttttggtata
    21481 aaaaatgaag tggcaagaga agttgttcgt gaggtaagaa acataacgaa actgccttta
    21541 gtaataaaat tatcacccaa tgcagaagat attgtaggaa tggcaaaagt ttgtgaagaa
    21601 gaaggtgctg atggagtttc attagttaat acttttaaag caatggcaat tgatataaaa
    21661 aatagaagac cagtatttga aaatgtatat gctgggttat ctggaccagc tataaaacct
    21721 atagctttga gaatggtaca tgaagtgtgt aaaaatgtaa atatacctgt aatgggaatg
    21781 ggcggaataa ctaaagccac agatgctata gagtttataa tggcaggagc tacttgtatc
    21841 caagttggaa ctgcaaattt tatgaatcct agaataggta ttgaaataat agatggaatt
    21901 aatgaattta tggatagaga aggaataaaa agtttagacg aaataagagg aattatataa
    21961 ggtagaataa atagtatttt aaagataaaa aatatagatt aaataaacaa taattttata
    22021 acattaacat ggaggaaaaa taatatgagt aaagtagatg tagtggatat attaaagaaa
    22081 agtgatgcat tgttggaggg acatttttta ttatcttcag gaaaacacag taatagatac
    22141 gtacaatgtg caaaagtatt aagatttcca gaatatgctg ctgaggtatt aagtacagtt
    22201 gttgaacaaa taaaagactt agatatagac ttagtagtag gaccagctat gggtggagta
    22261 atagtttctt atgagttagg aagacaatta ggaaaagaag ctgtatttac tgagagaaaa
    22321 gacaatacaa tggagttaag aagaggattt gaagttaaaa aaggagcaaa gataataatt
    22381 gctgaagacg ttgtaactac tggtaaatca actatggaga caaaaagagt attagaagcc
    22441 ttaggtggag aagttgtagg tgttgcatgt atagcagata gaactaatca tgatataggt
    22501 atgcctatat atagtgctat aaaacttgat attcaagttt atgaatctga tgagtgtcct
    22561 ttatgtaagg aaggaaaatt accagttgtt aagcctggaa gtagggagtt caaggaatta
    22621 gggatgtaat aaaaacttaa ttatttatag tgttacttaa aaaatgtaaa ttttttagag
    22681 taaaaatttg taatataaca tataacttaa aaataaaaag cagttagcct tataaatgaa
    22741 ggttagctgt tttttttgtt aaaaatatat ttacaaaata agagatagta gcagtacaat
    22801 ataagtataa ggtaaaagta ttatatatta gggaggggta agtatgaaaa atcaattaaa
    22861 tgaaaatcat aaaaaggttg tattttttgg agtaggtgct gtaggagcta cttttgcaga
    22921 acaatttttt aactctaaat atgattttaa aattctttgt gataatgaaa gaaagaaaag
    22981 atatttagaa gaaggattta taataaatgg aaaaaggtat gattttgatt atgtaactaa
    23041 agatgagtat aaacaagagg ctgattttat aattataggt ctaaaatata ataatttaaa
    23101 agaaaatata aaagaattag atggattagt tggaaaaaat acagttataa tgtctctgct
    23161 aaatggagtt gatagcgaag agataatagg agaaagattt ggaattgaaa aaatggtata
    23221 ttcatatgtt accaatatag atgcaaagaa aatcaataat aatattatac acactactaa
    23281 tgggataatt gtatttggta acaaagataa tagtgaagat agaaaaacta atataataac
    23341 cgaagtcttt gatgatgtaa atatagaata tactttatca aaagatattc aacgagatat
    23401 gtggtggaag tacatggtta atattggtgt aaatcaaact tcagctatac ttggtgcacc
    23461 ttatggagtt tttcagagtt ctgagcattt aagagaatta gcaaaatctg caatgaggga
    23521 agttgttgct atagcacaag caaaagacat atctcttaca gaagatgatg tggaacattc
    23581 attacataga atactagaac attcaaaaga aggaagaaca tcaatgcttc aagatgtgga
    23641 agctcataga cttacagaag tagatatgtt ttctaagaat atctgcaaac ttggaaaaaa
    23701 atataacata cctactccta taaatcagac tttcttttat atgataaaag taattgaaag
    23761 tagattttaa agggtctttg taagaaatat tgataattat tgattttaaa ttttattaat
    23821 gttatatact atttaagtta ctaaatattt ttaactcttc aatgaaaata gttgctgctt
    23881 ttgataaagt tatatctttt ggaaatatat atgagaaatg tctgttgtag ctgcttccaa
    23941 gctctatgac agacagctca ttgtttagaa caggtaagct tgtcactaga ttagagacta
    24001 ttgtaattcc taaattattt ctaacagatt ctttgacagc ataattactt ccaaaaacca
    24061 tcatactttt tggaataatt tctttaacac ttaaaaacat atctaaataa tctctggttc
    24121 cagaaccatc ctccctgact atccattttt ggttttgaag tttatcaaaa ctaaaatctt
    24181 ttaataaatg actcttgtat ggaagtgcta aaaccatctt atcttcaaaa aaatattctt
    24241 gaataaatga aggggaagag caagtgcctt caataagacc aatgtctaaa atataatcct
    24301 taacatgaga agatacgatt gatgtatttt ttataaaaac ttctacatct atgtcaggat
    24361 actttttaga aaataatgct agaaaatttg gtaaaatata ctctccaata gttaaacttg
    24421 caccaatctt taagtgacca gttatagcat ctgaaacttg gcttacatca tgataagtaa
    24481 tatttaaaag atttaatatt tctttagctc ttttgtacaa gatttgtcca ctttctgtta
    24541 taaaaatggt tttttgttta atagacctgt ttataagcac aactttaaaa taattttcta
    24601 gattttttat gtgtttactt acacttggtt gtgatagatt taaatattcc ccagctttag
    24661 taaagttttt gtattcaaca acagctacaa atgtttttaa ttcttcaaac aattttttgt
    24721 ctcctttacc taatgaaatt ttacattttt tatatacttt ctacagataa ttatactata
    24781 tataataacc attaaaaaca ttaatcatta cgatattata tatttatttt acttatggtt
    24841 attacaatta tatactattg ctatgaagaa aactatatta attataaggt aggtatatta
    24901 tgttaaagaa aaaaagcagt ttgacattaa aaactataag ggaaatatta ccaggactgt
    24961 ttgtatcagt attagtaggt tatattagta tatttatttc tattttaatt cctaaggtag
    25021 gggcagcatc aatttctata tttttaggta tgtttgtagg aaacctattt ttaaatcaaa
    25081 aggtatttca aaaaggttat aaattttcag agacagattt gttatcatat tcaatagtac
    25141 tattaggagc aacactcagt gtatctacct taatagactt aaaagtttca ggaattttat
    25201 ttataatatt gcaaatgaca ataacaataa tagctgcact ttatataggt aaaaaactag
    25261 gatttgaaga aaactttaga tttctaatgg caagtggaaa tgcagtatgt ggttcttctg
    25321 caataggagc aacagttcca gtggttaatg cgacagataa agaaaaggga attgcagtaa
    25381 ctattgtaaa tgttactggt atatttctta tgtttttact tccaataata tctcaatttt
    25441 tatatagcca tgaacttgta aaaacttcag caatgatagg tggaactttg caatcaattg
    25501 gtcaggttgt agcaagtgga gcaattgttg gagaaaatgt aaaagattta gctactattt
    25561 ttaagatagt aagagtaata tttctagttg ttgttgtatt agtatttgga catatgaaaa
    25621 atcaatctaa tagggaaatt cttgaagaag aaaaggatga gataaaaaag aaaaaagtga
    25681 ctataccatg gtatgtaatt ggattcttta taacttgtgc acttttttca atgaacatta
    25741 taccacaaga agtatctgtg ttgtgcaaag aaataagtaa caaactagaa ataatagctt
    25801 tagcagcaat tggattaaag gttaatgtaa aagatttagt gaaacaaggg aaagaagttt
    25861 ctttatatgg tttatttgta ggtatagtac aagttgtatc agctgtagtt ttaataaaaa
    25921 tatttatata gcataaaaat agtatttgta atattaattt gattaattaa aataatatga
    25981 tactaataat ttataatata aataaaaaat gaatttcgat aagtttaagt gggtataaac
    26041 ttatagaaat tcatttttta tttaaggtaa aaatttaaag taaaatatta ttttacataa
    26101 taataacctt ataaattttg aaattactta tctttgtgtt aaaataagta aaatgcacat
    26161 attagagcta agtttttaag taaataaaca aaatgaaaat ataaatatta aggagatttg
    26221 gtatatgaat gtttatgaaa aaggtaatgg agttatacta gaaggagtaa cagattttga
    26281 cccagtacat atatttgagt gtggtcaatg ttttagatgg cacaaacaag aagatggctc
    26341 atacactgga gttgcaaagg ggagaatatt aaatgtcaaa aaagagaatg ataaaatata
    26401 tttaaataat actaatttaa aggagtttaa cagcatttgg tataattact ttgatttagg
    26461 aactgattat acagaaataa agaataagct aaaaaatatg gatgaatatt taaataaggc
    26521 tactgaattt ggatggggaa taagaatatt aagacaagat ggatgggaaa tgcttatatc
    26581 atttataatt tcctctaata ataggattcc tatgatacaa agagctatag aaaatttatc
    26641 aagaaaattt ggtaagtata taggtgaata tgaaggtaat gaatactatg cattcccaac
    26701 accagaagaa ctaaataagg cctcacaaga ggaaataaga gcatgtcaaa caggttttag
    26761 agataagtac ataaaaagta ctacacaggc agttatagag aataatgatg aggtatctga
    26821 atatacaaat ttaagtactg aggattgtag aaaagagctt ttaaaattta atggagtagg
    26881 accaaaagta tgtgattgta ttgcattatt tggtatgcaa aaatatgatt cttttccagt
    26941 tgatgtttgg gttaagagag ttatgcaaga attttatata gatgaagaca tgagtttacc
    27001 taaaatgaga acttatggaa tcgataaatt taaagaaatg tctggatttg ctcaacagta
    27061 cttattttac tatgcaagag aactcggtat aggaaaataa attaaggggg agaaattatg
    27121 ggagtaatag gaacaatatt tctgttctat ttaattatat catatctagc tggagccata
    27181 atttctgtga ttatattgct tgaaaataga gaccctgcaa aaacaatgtc ttggctattg
    27241 atgtttatta tatttccagg tgtaggttta atgatatatg ctatttcagg tagaaatatt
    27301 agaaaaagaa aattatttaa gactcaaaaa ctagctaata atataaaaga aaagaaacta
    27361 tttgatacat tagaaaagat aacagaaata gttgaattag aaaaagaatc tataaaacaa
    27421 aataagcttt taagagatga agaggatggt agttatagaa aaagggtaat aaatatgttg
    27481 ttaaagactg gtatgtttcc ctttactaaa aataataaag tggatgtatt tgtagatgga
    27541 aatgaaaagt ttaaaagact tatagaagat ataagagaag ccaaagacca tattcattta
    27601 gagtacttta tcatcaaaga tagtgaaata ggtagggtgt taaaagaaga acttataaaa
    27661 aaggctaaag aaggcattaa gataagaatt ttatatgatg atgtaggatg ctggagattt
    27721 tggtttaata gaaaattttt ccgagaaatg agggaagtag gtatagaaat tgcagcattt
    27781 ttacctacaa aatttcctat aataggaggg aaattaaact atagaaatca cagaaaaatt
    27841 gttgttattg atggaataat tggatataca ggtggaataa atataggaga tgaatattta
    27901 ggcaaaaatg ataagtttgg atattggaga gatactcata ttaggattaa gggtatttct
    27961 gtatacatgc ttcaaatgac atttctgatt gattggtatt atacgacaaa agaagtatta
    28021 gtgactaaaa attatttccc aagtgtaggg aatgttggtg aaagtatgat acaagttgtt
    28081 gcgagtggtc cagacagtga ctgggaagat attcattatg cttatttttc tgcaatatgt
    28141 caggctagaa aaaatgttta tatagaaact ccatatttta ttccagatga aagtctacta
    28201 aaagctataa agagtgctgc tcttagtgga gttgatgtga gaataatatt tcctaaaatt
    28261 gcagaccaca agatagtaaa tatagcatct tattcatatt ttgaagaaat attaagagca
    28321 ggtggtaaag tttatttata taataaagga tttatacatt ctaaagtcgt aataatagat
    28381 gataaaattg cttctgcagg tacagctaat atggatttaa gaagttttat gcttaacttt
    28441 gaggtaaatg catttatcta tgatgaagaa gttattaggg taatgacaga tgatttcttt
    28501 gaggatttaa gtcactgtga agaacttaat ttggaggtat ttaagaatag aaatatcata
    28561 caaaaaatca aagaatctgt agcaagatta ttttcaccaa tattataaaa aattattaaa
    28621 aaaggtattg aaaattatgt gtgattggta tattataata attgttagca ctctattaga
    28681 tagagtgata ataaataaaa agtatatata taaatctaca tatataagta gtattaattt
    28741 aaaaataact aaaaacatag gcgaactagt ctatacttaa tattttagga ggcgtgaata
    28801 atgaaaataa gaccattagc tgacagagta gtaattaaaa aagtagaagc agaagaaaaa
    28861 actgcaagtg gaatagtttt accaggagca gctaaagagc aacctcaaat agctgaagtt
    28921 gtagaagttg gaccaggtgg aatagttgaa gggaaagaaa taaaaatgga attgacagtg
    28981 ggagataagg ttatattcca aaaatattct ggaacagaag ttaagataga aggacaagaa
    29041 tacacaatac taagacagag tgatgtatta gctgttattg aataaatata gaataaattt
    29101 attaggaggg gtttaaaatg gctaaagaaa ttaaattttc agaggaaaca agaagagctt
    29161 tagaagctgg tgtaaataaa ttagcagata cagtaaaagt aacattagga cctaaaggaa
    29221 gaaatgttat attagataaa aaatttggtt ctccacttat aactaatgat ggagtaacta
    29281 tagcaaaaga gatagaacta gaagatagat ttgaaaatat gggtgctcaa ttagttaaag
    29341 aagtagcaac taaaactaat gatgtagctg gagatggtac tacaactgct acagttttag
    29401 cacaagctat aataagagaa ggtttaaaga atgtaacagc aggggctaac ccaatacttt
    29461 taagaaaagg aatacaaaaa gcagtaacag tagcagtaga agaattaaaa aatcaatcaa
    29521 gaatagtaga aacacaagag gctatatctc aagttgcttc tatatctgct ggtgatgaag
    29581 aagttggaaa attaatagca gaagctatgg aaatagtagg taaagatgga gttataactg
    29641 ttgaagagtc tcaaactatg aatactgaat tagatgctgt tgaaggtatg cagtttgata
    29701 gaggatttgt ttctgcatat atggttacag atgtagataa aatggaagca gttttaaatg
    29761 acccatatat attaattact gataaaaaaa tatctaacat acaagaatta ttaccagttc
    29821 ttgaacaaat agttcaacaa ggtaaaaagt tattgataat agctgaagat gtagaaggtg
    29881 aagcattatc tacattagta gtaaataaat taagaggaac atttgatgta gtagcagtta
    29941 aagctccagg ctttggagat agaagaaaag aaatgcttca agatatagca atacttacag
    30001 gtgctcaagt aatatcagaa gaattaggtt atgatttaaa agaagctgat ttatctatgc
    30061 taggtagagc ttcatctgtt aaggtaacta aagaaagtac tacaatagta gatggttctg
    30121 gagataaaaa agctatagaa gatagagtaa ctcaaattaa acatcaagta gagcaaacta
    30181 cttcagattt tgatagagag aaattaatgg aaagattagc taaacttgct ggaggagtag
    30241 ctgttgtaaa agttggagct gctacagaag tagagttaaa agaaagaaag ttaagaatag
    30301 aagatgctct taatgcaact agagcagctg tagaagaagg aatagtagct ggtggaggaa
    30361 ctgcttttgt tagtgttata ccagcaatag gaacactaat tgagagttta gaaggagaag
    30421 ttaaactagg tgctcaaata gttaaaaaag cgttagaaga gccattaaga caaatagcta
    30481 taaatgctgg tcttgaaggt gctgtaattg tgcaaaatgt tgttaattct gaagcagaaa
    30541 ctggatttga cgcattgaat gaaaaatatg taaatatgat agaagctggt atagttgacc
    30601 caactaaagt tagtagaagt gctttacaaa atgctgcatc aatagcaagt actttcttaa
    30661 ctactgaagc tgctgttgct gaccttcctg aaaaagaaga tgtaggaatg ccaggaatgg
    30721 gtggcggaat gcctggtatg atgtaattta aaaaatttaa aatataaatt ttaatataaa
    30781 gaactatttc gacttagatt ttaaactcta agttgaaata gttcttttgt atatatctaa
    30841 tttttgtata tctataaatt caatacacat atttagataa tcagtatcta gtttgtaata
    30901 atattttaga gtagtattgt tattttttag gttatgattt tagatatata ttaattaagg
    30961 tataattgtt gatagagaat aaatcaaatt taaaaggatg cgataatatg gacttaagaa
    31021 aattgcttga agaagttaaa aatgaaaata ttgatataga ttttgcgtta gaaaagttaa
    31081 aagatttacc ttatgaagac cttggatatg caaatataga ccatcataga gaattaagaa
    31141 atgggtatcc ggaagttatt tattgtgaag gtaagagtga tgagcatatt ttagggatta
    31201 ttgataaaat gaatcaaaaa agttctaaca tattggggac aaggtgcaga aaagaaactt
    31261 ttctgaaaat taaagaaatc tataatcatg ctgagtacga agaggcgtct aaaattctta
    31321 agattcaaaa tcatgatata gagaatatag gaaaaggtaa aattgtgatt gctacagggg
    31381 gaacttctga tataccagta gcagacgaag cttatcatac agctaagttt ttaggtaatg
    31441 atgttgatag aatatatgat gttggagtgg caggtataca taggctttta aataaaagac
    31501 ataaaataga tagtgctaga gtaatagtag ccgttgcagg tatggaaggt gctcttgcaa
    31561 gtgtaattgg tggactggtt gatgttccag taatagctgt tccaacttct gttggatatg
    31621 gagcaaattt tggaggatta gcagcattac tagctatgtt aaatagctgt gcatctggaa
    31681 tatctgttgt aaatattgat aatggatttg gagcaggata tttagcatca atgataaata
    31741 aactgtaaat acattgatat aaattaaaca aaactatata ataaaattta atttctatta
    31801 tatttttact attaaaattg aggagacata tatgagtgaa aaaatacttt attttgatat
    31861 aataagcggt atatcagggg atatgaccct tgcaagttta ttaaatttag gtgtgcctaa
    31921 ggaaattttt ttggaggaaa ttcataaact aagaatgagc gatgaattta atataaacat
    31981 cagctcgaaa actgaaaatg gaatagtagg tacaaaagta gaagtaatta caaaagaaaa
    32041 acatacacat agaaatttag tggatatatt tgaggttata gataaaagca ctctaaacga
    32101 aaatgtaaaa tctaaagcaa aaaaaatatt tatggtaatt ggagaagcag aagcaaaagt
    32161 tcatggaact acaatagaca agatacattt tcatgaggta ggggctatag attcaattgt
    32221 agatatagta ggagcttcta tattagttga cttactttgt gtagataaag tttgtgctag
    32281 tacagtgtct gttggttcag gatttgtaaa atgtgaacat ggaattatac ctatacctgc
    32341 acctgcaact atagaaattt taaaaggtgt gccaattaaa ttaaataatg taaatggaga
    32401 atgtacaact ccaacaggag ctgcaatcat aaaagtcttg tgtgatgagt ttgtagatga
    32461 gcttgaattt tctccaaagc aaattggata tggtataggt cataagaagt ttgaagtacc
    32521 aaatatactc agaactgtat taggtgaaaa aaaaaagaag aattaattta tgaaattagt
    32581 gcaaacattg atgatatgtc ttcagaaatc tattcttatt tgtatgaaaa aatattagat
    32641 gagaaagcat tagatattta tacagagagc atttatatga agaagaatag accagcaaca
    32701 aaagtatcaa ttttatgtaa tgaatcagat ttagaaaaat ttattaaaat attactttta
    32761 gaaactagta cttttggagt gagatataat gcatataata gagaaattct agagagaaaa
    32821 tttgtaaaat tagatacaaa atatggagtg gttacagtaa aactagggta ttataaagga
    32881 aaactagtca aggctactcc agaatataat gaatgtaaaa ctatagcaaa aaatgaagat
    32941 attcctataa aaaaagtgtt tgctgatata aattttagaa taaaagaaga atttagtgaa
    33001 aacttattga cataagtaat aaattttgat aaattaatat tcagccttat taaataaaag
    33061 taaacagaaa aaaatatata aaatataaac tcactcgtat atgctcagaa atatggtctg
    33121 agagtctcta ccaagatacc gtaaatatct tgactatgag tgaaattatt ataccaaaag
    33181 acctagttaa gtaaatgtgt aggctgagtt aaactcccta tgtgttggct ataagataaa
    33241 ggtattttgg aagcctgtat agtaatttca cttttgctag aaattatgga agttactata
    33301 caggtttttt gtgtaaaaag atttaatata atttagactg tattgtgtta aaataaatat
    33361 ataaaaacta tattatacaa ggagagatgt aaatttatga aacatgaatt agtacttgta
    33421 atagattttg gaggacaata taatcagttg atagctagaa gagttagaga aaacaacgta
    33481 tattgtgaaa tacttccatg tactgcaagc atagaaagaa taaaagaaaa aaatcctaaa
    33541 gggataatat ttacaggcgg tccaaatagt gcgtatttag aagattctcc aacaatatca
    33601 aaagaaatat ttgaactagg agtaccaata cttggaatat gctatggtat tcaaataatg
    33661 tctcatgtat tgggtggagt tgtaagaaaa ggtaataaac aagaaaaaga atatggaaaa
    33721 acagctataa cttatggaaa atcatcatta tttgaaggaa taactacaaa tagtgtatgg
    33781 atgagtcata cagatttaat agaaaaagtt ccagaaggat ttactatagt tgcaaatact
    33841 aatgattgtc cagtagcagc tatggaaaat gtagaacgaa acctatatgg agttcaattc
    33901 catccagagg tagaacactg tttggaaggg gacaagatac ttacaaactt cttatataat
    33961 atttgtaaag taaaaggtga ctggactaca gattcattca tagaagataa aataaaagaa
    34021 ttaaaagaaa aaataggcga taaaaaagct ttatgtgctt taagtggagg agttgattct
    34081 tctgttgctg cagttcttat tcataaagca attggggaca acttaacttg tatatttgtt
    34141 gaccatggtt tacttagaaa aaatgaagga aatgatgtag aaagaatatt tagagagaaa
    34201 tttgatataa atttaataag agttaatgca gaagatagat tcttatctaa attaaaagga
    34261 gtttctgaac cagaagctaa gagaaaaata ataggtgaag aatttataag agtatttgaa
    34321 gaagaatcaa ataaattagg aaaaatggat ttcttagtac aaggaacaat ctatccagat
    34381 gttatagaaa gtggacatgg aaatgctgct actataaagt ctcatcataa tgttggtgga
    34441 atcccagaag atgtagactt ccaagaaatt gtagaaccat taagagagtt atttaaggat
    34501 gaagttagaa aaataggatt agagcttggt atagaagaag gattaatatt tagacatcct
    34561 ttcccaggac caggtctagg aataagagtt ataggtgatg taactaaaga aaaatgtgat
    34621 atattaagag aagctgatgc tgtttatatg gacgagctta gaaaagcagg tttatacaga
    34681 gaaatatggc aagcttttgc aacattacca gatgttaaga ctgttggagt tatgggtgat
    34741 gaaagaacat atgcttattt agttggttta agagcagtta cttcttctga tggaatgact
    34801 tctgactggt ataagatgcc ttatgatgta ttagaaagaa tttctaatag aataataaat
    34861 gaagttgatg gagtaaatag agtagtttat gatataactt ctaaacctcc tggaactatt
    34921 gaatgggaat agtaaataaa aaagtcgtaa gccttgtatt ttcaaggttt gcgactttta
    34981 aaaaaatctt tgtgatacta aaatgatact atatatttaa attatctagt ttttgggcaa
    35041 cttcaagttg cttatttggg tataaatgtg aatatgtatt ccaagttgtt tctacttttt
    35101 catgccccaa tctttctgct atagttaata tatttacatc catatttacc aataatgacg
    35161 catgagaatg tctcaaatca tgcactctaa ttctttttac attagataac ttacagcatc
    35221 tatctagctc tttagaaaga taacttttag caaatttaaa tattctttca ttatctttta
    35281 agtcatatag cttagataga taatctttta tattattata taagaaatgt gggataggga
    35341 caacacgttt acttttagga gttttaggag aagaaacaat atcctctcca tttagtctta
    35401 tgtagctttt ttcgacgctt attttatttt cgaaaatatc ttttggagta agagctaaca
    35461 actcccctag tctaagacct gtccaaaata aaatttcaaa tgctagtcta ggttctgatt
    35521 tcttttcaaa ttcaataaat tttttaaact cttctaatgt ccaaaagttc atttcatctg
    35581 cgtttttttt accgatagaa cctgccaaat gagcaggatt agaaggcaag ttataatatt
    35641 taactgcata atttaataca gcaacaagct ggttgtttat cgttttaata tatgtttggc
    35701 tataatcact ttttaataat tcgttttgcc atcttcttat atgtgttgca gtaatttcat
    35761 ttatttttag acttttaaaa aaaggtaaaa ttctaaagtt tattaaatac tttttagttt
    35821 ctaatgtaga taattttaat ctagaagaca tatcgtgcat gtattcttct atgagacttt
    35881 caaaactcat atcagtactc attttagatt tattcaaaaa ttctctttca aactctagag
    35941 cttctttttt agttttaaaa cctctcttaa ttttcttttt cctatcccca tcgaagtctg
    36001 taaaataaaa gctagcatac caactttttc tttgttcgtc tttgtaagca ggcattttag
    36061 acacccccaa ttatgtcatt ttaatattac aataattata acatgttaga tatgctatct
    36121 aaataattgt tttattttcc tcttcttttt atttcttgaa gcttgtaata tttacacagt
    36181 tctaagaagt cttcttctag tgctatagat aagtctaata tcgtagatat acctatatct
    36241 ttgtactctt gattttctag ttttgatata taacttctgt tacgtctcat tttttctgct
    36301 aattctagtt gtgtcattct tttctttttt cttaattttt tcaacattta ttaaaatcca
    36361 ccttttaatt atttttatga catttttata attaatagtt tgtgtaattt cttgtaaaaa
    36421 atgttcctca ttagaacatt ttttggtgga aaaatgtgtt aaaatgtaag taagaaaagc
    36481 actttcaaag cactataaaa atagtgctga aatagataaa caaataaaag taataaggag
    36541 gaaagataga ttctagaggg aaatcattat catttttaag aacgtatgtt cagttggtgg
    36601 gatagaaaaa tactttacag gggatggttt atttgaatga gaatgaaaat atgagtttat
    36661 atgtcagtaa gttaaaagaa gtattgaaaa ataattcaga agagtataaa aaaataagag
    36721 ctaaaataaa tgaaatttat aatctaaatg aaaagaaaga ataaaagggc tttagctctt
    36781 ttattctttc ttagtattaa ctgctttata ataagcatta tctatcattt tttttattgc
    36841 atttttatca tctgaatcta aagatgctaa tctatttatt agttcgttaa cttcattatc
    36901 ttcttttgag ttaacttttt ttaataattc atcatcttgt tgagtgttag gttgtatttt
    36961 acctaattta gttaatagct cctttaaagt taaatttaat ccaaaactca ttttttcaag
    37021 catatctaaa gtaggttcaa cagctttacc attccttggg tctctgtttt tttctatctt
    37081 atctatatat gtatggctca caccacaaag attagaaaat tctctaagag ataagttatg
    37141 ttcacttcta tattctttaa taatttctgc taatgtttgc ataatttcac acctcaccta
    37201 aataatagtt gacttaatta tatcagaaaa atgtaaacta ttgttaacaa aaataaaaat
    37261 ttagtaaaaa ataattgaca agagtaaaaa aaagacgtat actatgatta acaaaaaggt
    37321 tataaataaa gttaggaggg attaatataa aaaataattt acaatatatt agaaaagaat
    37381 ctagaatatc acaaaaaaaa ttcgctgata agataggtat atcaagaccg tatttatcta
    37441 gaatagaaaa cggtaaggtt aatccgagtt tagaaatagc gcataaaatc tcgctcgaaa
    37501 cagggaaaac aataaatgaa attttttttg attttactgt aaatcatagt aaactataag
    37561 gttttaattg taccttgaaa actaaatata aaatatttta aaggagcaag tatatgaaaa
    37621 ataaagaaaa agaaataatc attagaggaa ttttaatagg aattttttat tttttaggaa
    37681 ttgtatttag taatactttt tttaaataat aaatagaagg ggtaggtgaa ataccaactc
    37741 cccaaatcaa aataacactt tggaagttaa atatagaata ttcaaaagag gtgattagat
    37801 ggaaatagag caaacaacaa tacgcctgct aaaaagcaga cgaaagttga atattaattt
    37861 ctattttggt taggcgaaag acctaacaaa aaatctgtag atacattaag tttgttagaa
    37921 attaatatta aagtttctat atttggctct cttgaacccg attcataata ttgatatgca
    37981 cgttctgaga taccaaacaa actagcaaat tgcttttgag tcatattcat ttgctttctt
    38041 actagcttaa tattatcttt gaatttagtc ataactacac gctccaataa aaaaataaat
    38101 aaatttcttg acacgaacaa tattagcgtg taatatataa aacatagcac gaacaatatt
    38161 ggcgtgttaa ataaaaagga gagggtgaaa ataaataaca atttaaaact acaacgtgaa
    38221 aaagttggct taacgcaatt agaggttgct caaaaagcca aaataacaga gagaagctat
    38281 caatattatg aagctggcga acgtctccca aacattcgta cagctttaaa gatagctaga
    38341 attttaaata ctaattgtga aaaactcttt aatgaataat agcataaaag gactcagatt
    38401 acaagaaagg agctttagat atgaataatt tgcaacttaa caataaaaat acaataacaa
    38461 cattagaaat tgctgatatg ttagaaatta accattggga agtattgaga aaattagaag
    38521 gcacagaaaa aacaaaagga attattgata ttcttaacga caacaatttt gttgtggttg
    38581 attactttat aaaatcagct tatttagatt taaaaaatga aaatagaaaa tgttacaatg
    38641 taacgaaatt aggctgtgac tttttagcaa ataaatttac tggagaaaaa ggaattattt
    38701 ttacagctag atatgtaaaa agatttaata aaatggagca agagttaaaa gaacaacaac
    38761 ctaaactacc aactacatac aaagaagcat tacaacagtt attaatagaa gttgaagaaa
    38821 aagaacaatt acaattagaa aatcaagaaa aagataaggt aattcagtta cagcaaccaa
    38881 aagtattatt tgctgattcg gtagcgtctt ctgacaattc aatcctagtt ggagaattag
    38941 caaagttgct tagaca
//
LOCUS       DAMJVG010000036        38930 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.036, whole genome shotgun sequence.
ACCESSION   DAMJVG010000036 DAMJVG010000000
VERSION     DAMJVG010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 38930)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38930)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38930
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.036"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(212..823)
                     /locus_tag="PC512_001937"
     CDS             complement(212..823)
                     /locus_tag="PC512_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDF2441679.1"
                     /translation="MKMVKKLILSTIMALVLVLTIGCSNAEEKVKSNFEANLAALEMY
                     KYDEKGISDALTEAEYKQIQTYNSKDKVSMIAQLTPLYGKENAEKIYETIVKLIQGVE
                     KTVTVESSSKDKITLKVVSKALDTSKVMSEANTLVKSYVTDEKNYDKKEKEVQDDMTK
                     MIIDLYNKKPTKEVTTMITYTKKDGKWQPPSNIQKLCEGIYTI"
     gene            complement(915..1904)
                     /locus_tag="PC512_001938"
     CDS             complement(915..1904)
                     /locus_tag="PC512_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HDF2441680.1"
                     /translation="MLLLKKDDIKKVFTMRDAIEADKEAFRIYCEGKSVNPLRTNISV
                     PSQDASMLFMPGYIEELGCGGIKIVSVFPKNAQKGKPVIPATVLLLDGETGEVSAVLD
                     GTYVTQIRTGAASGAAIDVLAKKDSKIGALIGLGGQGEPQLEAMIEARNLDEVRVFSR
                     NKESREKFAEEMNLKLSKYNTKIVAVESSDEAINNADVIVLATPSKQPVLNGNLVKKG
                     ALISAVGSYMPDMQELCPNCLTRASKIFFESTDAVLSESGDILIPLKEGKISKDDFSG
                     DLGNVINGTIPGREDDDEIIVFKTVGIGVQDVVTAKRIYDKAKENGIGIDWKW"
     gene            complement(1971..2834)
                     /locus_tag="PC512_001939"
     CDS             complement(1971..2834)
                     /locus_tag="PC512_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 and DUF4163 domain-containing protein"
                     /protein_id="HDF2441681.1"
                     /translation="MKFFKVDTKAKVLRYVFVLTLTIMAVLAIKHDYKYNNLRKDASI
                     NLNSNKEAVTVMSNQSLPKGNTNSKQTLSVSTIGSKTIVKNDEYLESTINMPVITNSN
                     KIVERSTNDKIKNDIFEFYNKSYKEAKQYLKDNPDEKNKFVANVDFELKKNTDSALSI
                     KVRYYTYSGGAHGFYQDIAYNVDMRTGKFLELMDLFKDNTKYKEVIDEEIKRQIAELE
                     KKDEENIGIYNFKGIKENQNFYLQDENLVVYFDLYDITPYAAGIPEFSINKALISSML
                     KPEYVDLFDLK"
     gene            complement(2940..3536)
                     /locus_tag="PC512_001940"
     CDS             complement(2940..3536)
                     /locus_tag="PC512_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheB"
                     /protein_id="HDF2441682.1"
                     /translation="MERFNNMVIAIGASVGGTEAILEIIKDLPKSTPGIVVVQHMPAI
                     FTYMYAQRLDKQCIMNVREAKNNDRVEQGNVLIAPGGYQMKLCTDKQGYYVTCEKGER
                     ISGHCPSVDVLFDSVAEVAGKNSIGIILTGMGYDGANGLLKMKENGSFTIGQDENSCI
                     VYGMPMVAFDRGSVMLQLPLGEISNCLIRHINILKQKD"
     gene            complement(3576..4379)
                     /locus_tag="PC512_001941"
     CDS             complement(3576..4379)
                     /locus_tag="PC512_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-glutamate O-methyltransferase CheR"
                     /protein_id="HDF2441683.1"
                     /translation="MIKLTDEEFIVLVNYVKKEYGIDLSKKRALIEGRLYNTMIEKKL
                     SSFSQYMNLLFKDKTGNEAINLINRLSTNHTFFMREPQHFEFIQNSILPFWEENNKIR
                     NINIWSAGCSSGEEAYSIAMTLDDYFGYNKELWNIKIIATDISTNSLEKAKRGIYIES
                     NVNNVPELWKKKYFIDNKDGTFKICDKIRKSVIFKPFNLMNDFSYQHFDLIFCRNVMI
                     YFDLKTREELINKFYNATKKDSFLFVGHAEVINRSSTKYKYVKPAIYKR"
     gene            complement(4415..4855)
                     /locus_tag="PC512_001942"
     CDS             complement(4415..4855)
                     /locus_tag="PC512_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheW"
                     /protein_id="HDF2441684.1"
                     /translation="MAKDEIIKQVLTFYVNDVIYGIELENVIETIRFQSITYVPCLPT
                     YISGVINLRGRIIPVINMHIKYNLPKADYNERTCIIITKVDEYQVGIIVDKVVDVIHI
                     ENLNLLETTNSNNTNINKDIKEIAKVEDNSILILDIRKFLINSI"
     gene            complement(4868..6970)
                     /locus_tag="PC512_001943"
     CDS             complement(4868..6970)
                     /locus_tag="PC512_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheA"
                     /protein_id="HDF2441685.1"
                     /translation="MRQMLDMFIFETSLLLEQLDEIMIQIEKEKVFTHNNINETFRIM
                     HTIKGSASMMGLDNISALAHSVEDLFYAIREGKIEVLDNDLLFDLVFQSLDFIRRDID
                     ELQSRGCISSDYSNFIEGIEEYVSTLELSSSMKSKDNANLESKDEKEVIDSNFEYKED
                     SDVVKIIFEQGCMMENVRAFMLVFELRDYCEFIDFYPKDVETNAESTEYIKSYGFYIQ
                     FVAKEDKAIVYKTIEDNLYVKEYINISKKEIEMKNTSNNDAVENKLKDNNKVSKSYQN
                     NYTEDEIQEDVLNEKTDMEKDSLSEENEHLPISKQSIMSVNLEKLDLLQNIVGEIVIM
                     ESMVVNSVNSTGVDIDNFNKATRQLHKLTDELQDIVMSMRMIQIAGVFQKMHRIVRDM
                     NKKLDKNVELITIGAETEVDKSVIDNLAEPFMHLIRNAMDHAIEPIEERIAKGKEEVG
                     KIVLSAENLGGEAVISISDDGRGIMRDKILAKAKEQGLLKHQSNEYTDDEVNSLIMTP
                     GFSTKESITEFSGRGVGMDIVRKSIEKVGGSIEVKSKQDEGTTFTIKIPLTLSIVEGM
                     KFKVGDSLFTLPISSIRRTFKLTDLNQIITEGNKTELITIYGACIPIIRLHKIYNIQT
                     KVTNLMNGNMIIIENEHKAVCIFVDEIIGNQQVVVKPFPVYFNRFNIKNKGLSGCTIL
                     GDGSISLIIDADSIIEIY"
     gene            complement(7231..8934)
                     /locus_tag="PC512_001944"
     CDS             complement(7231..8934)
                     /locus_tag="PC512_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing protein"
                     /protein_id="HDF2441686.1"
                     /translation="MKREVKLSKLAIVLLIIIVLAVLAGIFSSISSYKAFEKVEKSIN
                     DMNNLRTQSQYIKDTTREISDVLRRYVFTGEKKNKDIYEKELYGKTRESALNKLEKIG
                     LTKSESNKILEAKEISDSLVPTEQSAIKAVESNDKSKAQSIIFGSDYINSQEKMDSLI
                     NEFQEDIVTRSNSKIVEVKKELQSLILRTIFILSLLIILTIIEYTVIKLKIVIPINKV
                     EKHFSRIASGDLRTSIDVEESKSEIGLLVSSVKKMQSMLLNYIDLIDSTLTSIAKGDL
                     RVEIDQEFIGDFKSIKISLESIINSFNGDFSEINLSAEQVASASEQVAAGAQALSQGA
                     TEQASSVEELASTINEISDGIKKCADSASLACEVSDQSASQVGFGSRCMDDMMTSMGE
                     ISEKSSEISKIIKTIDEIAFQTNILALNAAVEAARAGQYGRGFAVVADEVRSLAGKSA
                     KAAQNTAILIEEAIKTVENGVRIAKETANALDLVVNGVEKTTNYINGISSAVHSQEVA
                     ITQILSGIEQISIVVQMNSATAEESAAASEEMSAQAQILKELVEKFHLKESEVRESSW
                     V"
     gene            complement(8960..9919)
                     /locus_tag="PC512_001945"
     CDS             complement(8960..9919)
                     /locus_tag="PC512_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDF2441687.1"
                     /translation="MKNKQQGTILVVDDSVLMCDLIDKTLTKDNFKVKKAFNAIEAKE
                     FIEEFIPDIILLDIILPDNSGFEFCKEVKSNARTADIPIIFITSKNTDTDIVKGFGVG
                     AIDYMVKPFSMTELKARVIAHLEVKKSQDKLKKINNELESSLEKLNRLVVRDYLTGLY
                     NRRHIINQLMEQRRINKYSETSISLILGDIDDFKVINDTYGHEAGDFVLTVISSIIKK
                     NCRQIDTVSRWGGEEFLIMLTNTPIEGAKILSERIRKEIKEFDFNYKEHKIKCTITLG
                     VVEVNSNISLEENISLADKAMYEGKNLGKDCSVVSTMKGLKKI"
     gene            complement(10055..10573)
                     /locus_tag="PC512_001946"
     CDS             complement(10055..10573)
                     /locus_tag="PC512_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-binding chemotaxis protein CheW"
                     /protein_id="HDF2441688.1"
                     /translation="MRFPDDPYLDYGLIDEGIKYLKFRVDEQDFGVELEKVIEITGNQ
                     EIIFIPELPTYSKGIINLRGKIIPIIDMRLRLKKDELMTTNCMYIVVTEIKDLVVGFV
                     VDRVDDIVSLEKSKISPPPRVTIEYSDYFVSGVGELEGKIITLLDLEKLLTDKDEVLI
                     DELINGFDCTIM"
     gene            complement(10616..11101)
                     /locus_tag="PC512_001947"
     CDS             complement(10616..11101)
                     /locus_tag="PC512_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheD"
                     /protein_id="HDF2441689.1"
                     /translation="MNREIVVNIADMKIAYRPNVLVTYALGSCVGVCLIDKVAGIGGM
                     LHVMLPYSKDAINIENKCKFADTGINELIKSMENIGANRIYIKAKIAGGAQMFLGSSN
                     SVIASIGHRNVEAVKKTLLGLNIPILAEDTGMNYGRTIRFYTETGELLVDSINKGKKK
                     L"
     gene            complement(11098..11715)
                     /locus_tag="PC512_001948"
     CDS             complement(11098..11715)
                     /locus_tag="PC512_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheC"
                     /protein_id="HDF2441690.1"
                     /translation="MINYLELDDVHIDALREIGNIGSGNAITALASMINSNVEVLIPM
                     VKILEYNEATNLLGGPENKVVCILLDMKGDINGMFMFLLDESITQLMLSSLFNKEEAF
                     LDEIEAIEISAIKEIGNIMASSYVNAIASMLNMTISVSIPDICIDMVGAVLNVPMIRF
                     SDVGDKVLFIENKFKMSDNYFTSHILMIPEMSSLREILVRLGLEV"
     gene            complement(11780..12142)
                     /locus_tag="PC512_001949"
     CDS             complement(11780..12142)
                     /locus_tag="PC512_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HDF2441691.1"
                     /translation="MENKILIVDDAIFMRMIIKEALSKSGYNNLIEANDGEEACNIFK
                     YEKPDLMLLDITMPKKDGLEVLREIKKLDSSAKVVMCSAIGQENMIVEAIKLGALDFI
                     VKPFKTETLVKVVDNALK"
     gene            complement(12886..13383)
                     /locus_tag="PC512_001950"
     CDS             complement(12886..13383)
                     /locus_tag="PC512_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HDF2441692.1"
                     /translation="MNYEIVEINEKIVIGISKETTNKDGQAVNDIGELWKKFMGKGIY
                     NAIKGKKNDKTIGLYTDYQGDFTSPYSFVACCEVNSNSDKEKNLEELNTNNTVGESII
                     SKVIPAGKYAKFVIVGGQKEVGDFWFEFWQMDFDRTYISDFEEYQCNTFDTKKQEVHI
                     YIGIK"
     gene            complement(13558..14469)
                     /locus_tag="PC512_001951"
     CDS             complement(13558..14469)
                     /locus_tag="PC512_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YafY family transcriptional regulator"
                     /protein_id="HDF2441693.1"
                     /translation="MKINRLTEIIVILLNKKLVTAKELADRFEVSTRTIYRDIETLSM
                     SGVPVYMTKGKGGGISLIEEYSIDKAILSKKDKESLIVALKTLQATKYPEINSVVNKI
                     GSIFGEQNFSNWIEIDFTEWGSNFNEDDKFTKIKEAILRRNTINFNYVNSLSSQTNRT
                     VEPLKLMYKSKTWYLYGFCKLKDDFRIFRISRIRNLSIKDEVFSRKIIEEVCLNDSKV
                     IKENTITLKLRFKEKMLFRVFDDFNKDLITKNEDDTYDVITEFPIGEWIYGYILSFGD
                     NVEVLEPKDVRDNVITRLRELSKIYSL"
     gene            15394..16245
                     /locus_tag="PC512_001952"
     CDS             15394..16245
                     /locus_tag="PC512_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3100 domain-containing protein"
                     /protein_id="HDF2441694.1"
                     /translation="MEINKKHFIQVFLTCLILVVICEFIGQRTIAIGKASIVLFPMLY
                     AVIIGLIITPDLLGKKIKALKKVVGEKEINIAGEVVGIALVMLGIKYGTTVGPNIDKI
                     IQAGPAFIAQEFGHILAPIVALPLALMFGMKREAVGATASISREPSLGVISEKYGINS
                     PEGSGVLGTYLMGTVLGTIYFSVLGSISIYSGLHPYALGMACGVGSGSMMTAAAGSLS
                     TMVPPEMADTILAYAATSNMMSSITGIIFLVFVSLPFTNFMYKILEPKFSRNKKTKEI
                     KSTEGEC"
     gene            16249..16719
                     /locus_tag="PC512_001953"
     CDS             16249..16719
                     /locus_tag="PC512_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441695.1"
                     /translation="MFANLNLKKSSYQLLVMSVIGVIILIGQRISVGTSIVTALPGMV
                     MLILAAMAAMIIKDLFPKSIFPAFGFATIIGLLLSMPYSPTSEVFLTNTNNINFMAIT
                     TPLLAFAGISVGNKIEALKEMSWKIVIISLIVFTTIFFACASIAHIVLSIQGKI"
     gene            16732..18042
                     /locus_tag="PC512_001954"
     CDS             16732..18042
                     /locus_tag="PC512_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2441696.1"
                     /translation="MNKEQLKSLVIKTIDENREKILKIGQGIYKNPEYGYKEFKTTEA
                     VSNFFEQELNLSVEKNIAVTGCKADANSSKKGPHISILGELDGISCKEHKDANEIGAS
                     HTCGHNIQIAGMLGAAVGLVKSGVLEHLDGKVSFMATPAEEFIELEYREQLKKEGKIT
                     YFGGKQELIKRGYFDDIDISMMFHASDLGEDKALVGPESNGFVGKKVKFIGKESHAGS
                     APHDGINALNAAMLAINNVNALRETFKESERVRFHPIITKGGDIVNVVPADVHMESYV
                     RARTINGMIDANERINKALMAGGMAVGADVEITEIPGYLPILRYKSLDNLFKNNLEDL
                     GLKGKVIDGGDFTGSFDFGDVSHIMPTLHPMIGGVKGALHTRDFEIVDEDLAYIIPAK
                     AMALTVVDLLFDNAKDAKDILDTFTPVMTKEEYLTFLEKHDKTL"
     gene            18254..19000
                     /locus_tag="PC512_001955"
     CDS             18254..19000
                     /locus_tag="PC512_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2441697.1"
                     /translation="MFNAGNRIINTWLYPIQDGFVLIDTGYENGFKHFKKRISKFNIK
                     IKDIRYIFLTHAHDDHVGFLNQILDESPNTKIVMHDKALEILYKGQNSFIGGCTSRTA
                     FLFCQIMKLFGKGEHSFSPLKQEFEKRCILVSDKNRKEIEKELNGKIIDTPGHTADSI
                     SLLIDEGVLFCGDSAMNGFPSTHKITIFAESKLEFIQSWKTIINTKPKMIYPGHGKPF
                     EYSKLEQNLIYVNKINLYPLHNSKDIHRFL"
     gene            19362..20903
                     /locus_tag="PC512_001956"
     CDS             19362..20903
                     /locus_tag="PC512_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HDF2441698.1"
                     /translation="MNDNVVKKKNFFDRTLNRIETVGNKLPDPVTIFLGLCVLLLILS
                     SLVGSMGISVVHPGTGETITAVNLLTVEQLQILLGNIVSNFQGFAPLGLVLVTMIGAG
                     VCDKTGLMTATIKASVSKIPETRVTLVVMTIGMLANIASDAGTILFPPLAALVYLGVG
                     RHPLIGLFSGYAAVCLGFAANIMISVNDILAASFTVPAAQMIDSGFQANATMNLFFMI
                     ASTFVLILLATWVTEKIVAPRFGKYEGNAELDVDGSLSDVEKKGLKKAGISILIYVAI
                     IVALSVIGKKPFLADPETGDLLSNNAPLMKGMVPIIALAFFIPGVVYGKTIGKIKKDK
                     DVVSIMASAMSDMGGYIILAFAASQFLQLFTNSNLGLILAVKGGEFLKSAGINGPLLL
                     IGFIILSCFINLFIGSASAKWAILAPIFVPMFMMVGYNPALTQMAYRIGDCITNPLSP
                     LFPYFPIILAFTRKYDKDAGMGTVIANMIPYSISFLIVWTILLILFMVFNIPLGPGIL
                     PSYSM"
     gene            20938..22044
                     /locus_tag="PC512_001957"
     CDS             20938..22044
                     /locus_tag="PC512_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HDF2441699.1"
                     /translation="MLDKNRLINNFMDMVRIDSPSNQELEMSKWLVNYLKERNIDAII
                     DDAGEKYGGNTGNVIAYIKGEEGSRPLCLCAHMDQVQPCLGVKPILDGNVVRSDGTTT
                     LGADDKAGIAAILEALEHVITEKIPHRDIYLCFTICEEAGMHGVKNFNPDNLPCKDMV
                     ILDSGGAIGSIAYKAPAQQSIKISFHGKKAHAGIEPEKGLNAILVASHAISNMHIGRI
                     DSLTTSNIGKIEGGGATNIVTDKVTLTAEIRSHIPETLEYELNHMEKCCKDAASKFNT
                     TYTFEHSMSYPSFELSRDSHVFKLSEEAIRQVGVVPNPMVIGGGSDANILANLGYNCA
                     ILSLGMYDVHTVNEYVNIDELYDTAKIVYHMIKL"
     gene            complement(22375..23661)
                     /locus_tag="PC512_001958"
     CDS             complement(22375..23661)
                     /locus_tag="PC512_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDF2441700.1"
                     /translation="MIVGIIGPSDSGFKIKDDLKQIDSDLKTKIYVREKVVDTIEVIS
                     KCEDECDAIIFTGCAVYEFIKSKYEISKPHSFVPRSGTSIMKAFWAIKSANIKLDKFS
                     IDVVDRYVVEDALKEFDIKATSVFCNPFSLEVGESELVEWHIKLFEENKTDIMLTGFG
                     AVYNELKERGYPVFRLQATIQLIKESYDKVKSEYALSKARFSQIAVEILSLIDYKEKI
                     DNYYSDMIKKSDMDKLVVNYVRSIQGSLFLLGRNDYVVFVHKGVADNEYNYDKLFNLK
                     REIKDMGFSLSIGIGTGVTAYQAENNAHKALRHSIDSKEIGIYLVDEDENIRGPLASE
                     NELNYSLMLSDEKVIEISKKTGMSCESVAKIIAINENRKSKIYDSKELAEYLNVSERS
                     ARRILNKIVNAGLGRICAKETSIGGGRPKNITEILF"
     gene            complement(23784..26882)
                     /locus_tag="PC512_001959"
     CDS             complement(23784..26882)
                     /locus_tag="PC512_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HDF2441701.1"
                     /translation="MDVINLIDELDEIVYVSSLDTYELLYINEIGKKAMGLNDISHLK
                     CYKALQGKDSPCEFCTNSILKEDEYYIWENTNTRTNRHFILKDKLIKWEGKHARLEIA
                     LDITEKEDISKSIAEKLEIKELLVGCIKHLITESNFSDAVNLVLTNIGKFHKADRAYV
                     FEVSEDRTKVTNTYEWCNEGVDEQKQALTNLDINELKNWFLLFEQKGFVIIDDIENIK
                     EEQPIEYEILKPQKIESLMTSSLKQDDKVVGFIGVDNPHKAVGDTSLLTSLSYFLLTE
                     MKKRKVENKLNYMSYYDFLTGAYNRNKYIKYIDNFQKGKVKSIGVVFVDINGLKDIND
                     NFGHANGDSAIVSACVIIKKYFHSYNVYRIGGDEFVVLCEDISKQLFEELVSWLSEEF
                     KDEMIYSVAVGSIWSDDNIDIHKLIKVADERMYQDKKRYYNKNKLRNNEMKVISDLAD
                     STNNILFKHKELVDKVYFDDLMIKGYSKAYEKLAYNTYDIILSICIDTNLITPIYQSE
                     SNIFSFPIKENLEKTFSYIKKYLIHPDDIILFNDNHLLKSLDSLNNSKQDDLELNFEY
                     RRLGIDKKYYWALIYMLKISSKNKLGEKQTHILVAIKNIDYLMQLHKNQKDTLTGLYN
                     YESFCEQISLMLKRYPDKRYAIIMMDIDKFKVINDIYGVRGGDKALIYVAELIQKNIG
                     SNGICCRMYADVFCIFYESYSDRDIHKVIYKIKNSLNRKKFEYMLVPCFGVYRILDNH
                     IPITNACEMAGYAHKKVKKQSINNYIFYDDTIRNDALEEKQMEREMEYALENGQFHVY
                     LQPKYNLNANKIVGAEALVRWVHPEKGIIPPIKFISLFEKNGFIIRLDMYVWEQVCSL
                     IRKWIDLGEEPVPISVNVSRLHLHNPHFKEIVLSLINKYSIPKSFLELELTESLFIKN
                     IKLFTKIIADLRMDGIVLNMDDFGSAYSSLNMLKNINIDTLKIDCGFFNEEGITDREK
                     IVLKHTIAMAKDLDMDVVAEGVETKEQAEFLVSLDCVVIQGYYYCKPIPSSDFEKLLY
                     QK"
     gene            27607..27759
                     /locus_tag="PC512_001960"
     CDS             27607..27759
                     /locus_tag="PC512_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441702.1"
                     /translation="MKIFSFLLFVVGICFCIAGFMGHSSAFSGATLSFFATTMIAVRQ
                     VKTKKK"
     gene            complement(28052..28756)
                     /locus_tag="PC512_001961"
     CDS             complement(28052..28756)
                     /locus_tag="PC512_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2441703.1"
                     /translation="MEIKPLVLIVEDDKPICKFIKVSLETQNYRCVETDNGGTAISLI
                     HSLDPDLIILDLGLPDIDGIEVIGRVRACAKTNKIIVVSAREHERDKVEALDGGADDY
                     LTKPFSVTELLARVRVALRNKAQQDNINNDAPKSFEVKNLKIDYENHIVSINGEEIHL
                     TPIEYKIIELMSKYSGRVLTHKFIIDKVWGNYYESENQSLRVFMASIRRKIEKNPAQP
                     EYILTEVGVGYRMADE"
     gene            complement(28747..30354)
                     /locus_tag="PC512_001962"
     CDS             complement(28747..30354)
                     /locus_tag="PC512_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4118 domain-containing protein"
                     /protein_id="HDF2441704.1"
                     /translation="MKKERLQHEDLKEYDYDEDGYLSKKIIIKDFIKTILVMTIATGI
                     SVVFEKVGFNESNIILVYILGVLFATSITYGYFFGILSSVIGVLSFNFFFTHPLYTFL
                     AYRKDYPMTFCIMLMAAIITSTLTSRIKREVRLSHKREKMIRLLYENNKTLLKAKNKN
                     QIIEFCGSNLVNILNRTVIVTIADENNNLGKPSIYICNNDGSENIFHSVLEKEAIKEA
                     FRTGNPVGIGTKYCKNSSAYYFPIKGQESNVLGVIGVACFKIDIITENEKILLEAVST
                     QVALAIDRENLFEKNKKANLEAERERLRGNLLRSISHDLRTPLTSILGSSSTILENDD
                     VIDKETRVELLKNIYEDTSWLTHSVENILSMTRIDEGKLDIEKRPEVVDEIIAESILR
                     VKKFANSRDIKTNIPDEIIIVHVDVLLIEQVLVNLIDNAIRHTPKNSKIELTVKKESN
                     QVLFEVADNGKGIPNEDIGNIFNRFYTKNKSRNLERRGIGLGLEICKSIVEAHGGEIV
                     AFNNPSGGATFRFSIPMYDEEGKDKWK"
     gene            complement(30608..31786)
                     /locus_tag="PC512_001963"
     CDS             complement(30608..31786)
                     /locus_tag="PC512_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441705.1"
                     /translation="MEKLSDKRRVKAVSMETFVFIVLLAVGFGYVGSIMGAGMMFKVI
                     MSTAHALLLDTVFLIMAMAVLAGALSALLSEFGVISLVNKIFKGLMRPIWGLPGASIA
                     GVVATYLSDNPAIIPFAKDKTFTQYFKKYQVPALCNLGTAFGMGLIVTTFMIAQGKEY
                     VLPAIIGNVGAIIGSIISVRIMLTFTKKYYNYDPKNDTEKQINDKGAKLEEFREIRDG
                     NVFQRTLDAILEGGKLGVEMGMAIIPGVLVVCTLVMLLTFGPSTDPATGQAVYTGAAY
                     EGIKLLPAIGDKISFIIEPLFGFTSPEAIAFPVTALGAVGAAISLVPEFIKSGAITPN
                     DIAVFTAMGMCWSGYLSTHIGMMDALDARPLAGKAILSHTIGGLCAGICAHFIFMLVG
                     "
     gene            complement(32012..32506)
                     /locus_tag="PC512_001964"
     CDS             complement(32012..32506)
                     /locus_tag="PC512_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HDF2441706.1"
                     /translation="MHLFIEVIAAFFTALSFGVLFNMKGKNLILAGIGGSIAWFSYKF
                     LLNMGVTENLCFFIATVCFAIYCELCARIYMTPATTLSVCCLIILVPGYGIYNTMYSV
                     LTNNYIKAVEYGVSTLSCASSIALGLVFITTVFRKVNLYGVLTKIKENEKYKKSINKI
                     KQQK"
     gene            complement(32507..33268)
                     /locus_tag="PC512_001965"
     CDS             complement(32507..33268)
                     /locus_tag="PC512_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HDF2441707.1"
                     /translation="MDIDRILNFSSNAGKAMLQSGGETYRVEETIARICQSFGIDHVD
                     VFATPTAVMASVFVDGKLHSAIKRISSRRVDLNLVHEVNSLSRAISINNLDIELCEKI
                     LDEISEDNYYSDLITIFFAGIAAATFSILFGGNVEEFIAAFTVGILTKFVIMYLSKSS
                     LNDFFVNAIGAVIIASCSILILKLGFIKTLDHLIAGAIMLLVPGLALTNALRDLLDGQ
                     LISGLAKLAEVFFVGVSIAVGMFLVLGLYFKLGGI"
     gene            33990..36824
                     /locus_tag="PC512_001966"
     CDS             33990..36824
                     /locus_tag="PC512_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2441708.1"
                     /translation="MLRKDKVLLSLHKLCENMTLKDLQSDKTGFTTIEIANHSSLDRS
                     NTSKELNNLYNEKKVLKISGKPILFLHASIIENLIGRTLNSDEFSINNCNELLKSSKN
                     DSEDIFSTLLGHDSSLKLPIEKAKSAILYPPKGLNTLLIGPTGVGKSTFAETMYKYAV
                     ESKIFSSESKFVVFNCAEYAENANLLLSNLFGYVKGSFTGANKDKFGIVAQADGGILF
                     LDEIHRLPPEGQEMLFLLMDKGIYRRLGESDIVHKANVFIVCATTEDIHSSLLGTFLR
                     RIPVTINLPALQDRSLKERLSLIKYFFIIESKYTNATIKVHKDVIKSLLLYDCFGNIG
                     QLKSDIQLMSARAFLNYKTGLKDNIEIDLSLVPDYIYIGLLKLNENRSNLNKLSELDY
                     MLFYEFNGNNLEVEYTKELSKYNIDTSNNGFKYSTEIPYLENDIRSMFINYMEKYSTK
                     LLSISSVTHSDYTSNEIFKVINPKIYYAVEHSLKEAEKISRNKYTKQTYIALSMHISA
                     LIENINQDTYNPKYNLYNDKIFLDKDLNIAKIVLSIIENDLQTSLPKDEVKFISMFLN
                     SMYLEPNNQSESIGVIILAHGNSTASSMCDVANSLLGTNHCNAIDMPLDVKVSTILDK
                     TIELVKECDEGKGVLLLTDMGSLIAFGELISEKTKIKTRSIEMVSTPIVLEAVRKSTL
                     PEMTLDELANSLSSLNPYIGRAAIDSTEINYPEKSREYVIITTCITGYGSAMKVADFI
                     NSSLKNISKYNINLVPHNIESFKMYKNKFSNTKILAVVGSVDFNVANTPFIHIEELLN
                     GYGLDMLNKIIEGTFNANSITNIKETNLSYNSLIINFMTQNLELLDSVKLFNYVNSSL
                     FTIIELIDENLKSKFKLGYILHCSFMIERCFKNTTFPYNNITELISKNHELYSLIREA
                     FKPTEAYFNILIPDEEIAYIIDMINEYLNK"
     gene            36867..38111
                     /locus_tag="PC512_001967"
     CDS             36867..38111
                     /locus_tag="PC512_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HDF2441709.1"
                     /translation="MEDEILKGKIKQLTILALIFIFITPVFAFADTPPVPNSSRAALL
                     IDQETKRILFEKNIDEKMPLASLSKMMTFLLAIEAVDKNQVKETDMVKIDKSTASVGG
                     STCKLKDGDEISLGELMQGLMLVSGNDAAIAIAKHIGKTEKNFVNMMNKKAEEIGMID
                     TYYFNPNGLPIYTDPEHKEPPIENMSTAHDIVTLGKYMYDHYENQVTRITTMQVYNDT
                     KKDFTHYNTNPLLVSVPGVDGIKTGYTDNAGYCLAFSMMVPKDAKNERNHRLIGVVLG
                     DGNKKNRISSSATLLKYGKDNFHSKKIAHKGDIIETPCVDGIDDFKITVKVDKDLYGV
                     VSDNENINPKVVFKNMNYPIHKGDIVGVVKYYNDSGKFVGSVDVKSESNIGCIPLKDK
                     IKIKVAKINKKLEIKNSVCFKA"
     gene            complement(38651..>38930)
                     /locus_tag="PC512_001968"
     CDS             complement(38651..>38930)
                     /locus_tag="PC512_001968"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441710.1"
                     /translation="EEKIAEVTKLVGKVTADNLEASKVTLKAATDAIEEAKTAGWTES
                     EVQSFAGYEDIAKVQGEITALEPSSTIFRANLFSTLTRFVTDSFKINK"
BASE COUNT        13087 a         6474 c         4518 g        14851 t
ORIGIN      
        1 tatttaataa aaaaattacc taatacagta aattaattgg taagataaat tatttattat
       61 tagtaaagta aattatttac tatttatcaa gataaattat ttataaaata aatcatttat
      121 aaaatataat ttatactttg aaaataaaat aaactatctt ccaaacattt tattatatgc
      181 ttaaaagata gttttgtgtc tttaaaataa attaaattgt atatattcct tcacataact
      241 tttgtatatt actaggtggt tgccatttac catctttttt agtatatgta atcatagttg
      301 taacttcctt agttggtttc ttattgtaaa ggtctataat catttttgtc atatcatctt
      361 gaacttcttt ttctttttta tcgtaattct tttcatcagt tacataagat tttactaaag
      421 tgttcgcttc actcattact ttactagtat ctaaagcttt acttacaact ttcaaagtta
      481 tcttatcctt actagaagat tccactgtta ctgtcttttc aacaccttga attaatttaa
      541 caattgtttc gtatatcttt tcagcatttt ctttaccata aagaggtgtc aattgagcaa
      601 tcattgaaac cttgtccttg ctgttataag tttgaatctg tttatattca gcttctgtta
      661 atgcatcaga aattcctttt tcatcatact tatacatttc taatgcagct aaattagctt
      721 caaaattcga ctttactttt tcttctgcat tagaacaccc tatagttaga actaaaacta
      781 gagccataat cgtagataat attaactttt ttaccatttt catacaaaca tcctccctca
      841 attaaaataa taaaaaattt atttatcaac attataacat aaatttgtct aactatagaa
      901 ttattttgaa tattttacca cttccagtct attccaatac cgttttcttt tgctttatcg
      961 tatattcttt ttgctgttac gacatcttgt acacctatcc caacagtttt aaatacaatt
     1021 atctcatcat catcttctct tccaggaata gttccgttta taacattccc taaatcacca
     1081 ctaaaatcat ctttacttat cttaccttct tttaatggaa ttaatatatc tcctgactca
     1141 gataaaactg catctgttga ttcaaaaaat atcttagacg ctctagttaa acagtttggg
     1201 cacaactctt gcatatctgg catatatgaa cctactgcac ttattaaagc tccttttttc
     1261 actaagtttc cattaagtac tggttgtttt gatggagtag ctaaaactat cacatctgcg
     1321 ttatttatgg cttcatcaga tgattcaact gcaactattt tagtattata tttacttaat
     1381 tttaagttca tttcttctgc aaatttttct ctactttcct tgtttctact aaaaactctt
     1441 acctcatcca aatttctagc ttctatcatg gcttcaagtt gtggctcacc ttgtcctcct
     1501 agacctatca aagctccaat cttagaatct tttttagcca atacgtctat agctgctcca
     1561 gaggctgctc cagtacgaat ctgagttaca taagtgccat ccaatactgc actaacttct
     1621 ccagtttctc catctaataa tagtactgtt gctggaatta ctggtttgcc tttttgagca
     1681 tttttaggaa atacagatac aatttttatt cccccacagc ctaattcttc tatgtatcct
     1741 ggcataaata acatactagc atcttgactt ggaacagata tattggttct caaaggattt
     1801 acactctttc cttcacaata aattctaaaa gcttccttat cagcttcaat tgcatctctc
     1861 attgtaaata ctttttttat gtcgtctttt tttaaaagta gcatttttat acccccaatt
     1921 ttaataagtc tctatgctaa atattatagc ataacattta atttaatctt ctatttcaaa
     1981 tcaaataaat ctacatactc tggttttagc atagaactta tcaacgcttt atttattgaa
     2041 aattctggta ttcctgctgc atatggagtt atatcatata aatcaaaata tacaactaga
     2101 ttctcatctt gcaaataaaa gttttgattc tcttttatac ctttaaaatt atatattccg
     2161 atattttctt catccttttt ttcaagttca gctatttgtc ttttaatttc ttcatctata
     2221 acttctttat atttagtatt atccttaaac aagtccatta attctaaaaa ttttccagtt
     2281 ctcatatcca cattatatgc tatatcttga taaaatccat gtgctccacc actataagta
     2341 taatatctca cttttatact aagagcagaa tcagtattct ttttaagttc aaagtctaca
     2401 tttgcaacaa acttattttt ctcgtcagga ttatccttaa gatactgctt tgcttcttta
     2461 tatgatttat tataaaattc aaatatgtca ttttttatct tatcatttgt agacctttca
     2521 acaattttat ttgaatttgt tattacaggc atgtttatag tactttctaa atactcatca
     2581 tttttcacta ttgttttact tcctattgta cttactgata aagtttgttt actatttgta
     2641 ttaccctttg gtaatgactg gttactcata acagtcactg cttccttatt actatttaaa
     2701 ttaattgaag catctttcct taaattatta tatttatagt catgtttaat tgccaaaaca
     2761 gccattatag tcaatgttaa aacaaataca tatcttaaaa ctttagcttt tgtatcgact
     2821 ttaaaaaatt tcatattatc attttcctcc taaatataaa tctctcttat tatatttgga
     2881 gtttctaggg ttttttatcc atataattta ataaaagatt aatttttatt tataaaaaat
     2941 taatcttttt gttttaaaat attaatatgt cttatcaaac agtttgaaat ttcaccaaga
     3001 ggtaattgta acataacaga acctctatca aaagctacca ttggcattcc atatactata
     3061 caagaatttt catcctgtcc aattgtaaat gaaccatttt ctttcatttt taaaagtcca
     3121 tttgctccat cataacccat acctgtaagt attattccta ttgaattttt acctgctact
     3181 tctgctactg aatcaaacaa aacgtctact gatggacagt gaccacttat tctttctccc
     3241 ttttcacaag ttacataata tccttgttta tctgtacaca atttcatctg gtaaccccca
     3301 ggtgcaatta acacatttcc ttgttcgact ctatcattat tcttagcttc tcttacattc
     3361 ataatacact gcttgtcaag ccgttgtgca tacatataag taaatatagc tggcatatgt
     3421 tgaactacaa caatccctgg tgttgatttt ggtaggtctt ttataatttc aagtattgct
     3481 tctgtaccac ctacagatgc gcctatagca ataaccatat tattaaaacg ttccacatta
     3541 ccgcctccaa aaaatcatat atcaaaaata cctttttatc gtttatatat agcaggtttt
     3601 acatatttgt atttagtact acttctgttg attacttctg catgtcctac aaacaaaaaa
     3661 ctatcttttt tggtagcatt ataaaattta tttataagtt cttctcttgt ttttaaatca
     3721 aaataaatca taacatttct acaaaaaatc aaatcaaaat gttgatatga gaaatcattc
     3781 attaaattaa acggcttaaa aattacactt tttctaatct tatcacaaat tttaaatgta
     3841 ccatccttgt tgtctataaa atacttcttc ttccataact caggaacatt gttaacattt
     3901 gattctatgt atatacctct tttagctttt tcaagtgagt tagttgaaat atctgtggct
     3961 atgattttaa tgttccacaa ctctttatta tatccaaaat aatcatccaa agtcatagct
     4021 attgaatacg cttcttctcc actagaacat cctgcactcc atatatttat gtttcttatt
     4081 ttattatttt cttcccaaaa aggaagtata ctattctgta taaactcaaa atgttgaggt
     4141 tctctcataa aaaatgtgtg gttagtactc aatctattta ttaggtttat agcttcattt
     4201 cctgtcttat ctttaaataa tagattcata tattgactaa aagaactaag ttttttctct
     4261 atcattgtat tgtataagcg accttcaatt aacgctcttt ttttacttaa atcaatacca
     4321 tattcttttt ttacatagtt tacaagaact ataaattctt catctgtgag ttttatcatg
     4381 caaaaacttc ctcctgctaa tttatcagaa ctaactatat gctattaatc aaaaactttc
     4441 gaatatctaa aattaatata gaattatctt caactttcgc aatctctttt atatctttat
     4501 taatattagt gttgttagaa ttagtcgtct ctagtaaatt tagattttct atatgaataa
     4561 catcaacaac tttatctaca ataattccaa cttgatactc atcaaccttt gtaattatta
     4621 tacaagttct ctcattataa tcagctttag gaagattgta ctttatatgc atattaataa
     4681 ctggtattat tcttcctctc aaattaataa ctccacttat atatgttgga agacatggta
     4741 catacgttat tgattgaaat cttatggttt caatcacatt ttctaattct attccataaa
     4801 taacatcatt gacataaaat gttaatactt gtttaataat ttcatcttta gccatacttt
     4861 aaatccccta atatatttct ataatgctat ctgcatctat aattaaactt atacttccat
     4921 ccccaagtat tgtacatccc gataaaccct tattttttat attaaatcgg ttaaaataaa
     4981 ctggaaatgg tttcacaaca acttgctgat tacctattat ttcatcaaca aaaatgcata
     5041 ctgctttatg ctcattttca ataattatca tattaccatt catcagattg gttacttttg
     5101 tttgaatatt atatatttta tgtaacctta taatgggaat acatgctcca tatattgtaa
     5161 ttaactctgt cttatttcct tctgtaatta tttgatttaa gtctgtaagt ttaaatgttc
     5221 ttcttatgga tgatattggt aaagtaaata gtgaatctcc aactttaaac ttcataccct
     5281 ctactataga aagagttaat ggtattttta tagtaaaggt tgtcccttca tcttgtttac
     5341 tttttacttc aattgaacct ccaacttttt caatactttt acgaacaatg tccatgccta
     5401 ctcctcttcc agaaaattca gttatagatt cttttgtaga aaagcctgga gtcataatca
     5461 aagaattgac ctcgtcatca gtatactcat tactttgatg tttaagaaga ccttgttcct
     5521 tagcttttgc caaaatctta tctctcataa tgcctctacc atcatctgaa atacttatca
     5581 cagcttctcc gcctagattt tcagcagata aaactatctt tcccacttct tctttacctt
     5641 tcgctatacg ctcctcaata ggctctattg catggtccat agcatttctt ataaggtgca
     5701 taaaaggttc tgctaaatta tcaattacac tcttatctac ctctgtctct gctcctatag
     5761 ttattaactc tacattttta tctaattttt tattcatatc tcgtacaatt ctatgcattt
     5821 tttgaaatac accagcaatt tgaatcatac gcatagacat tactatatct tgcaattcat
     5881 ctgtaagctt gtgtaattgt cttgttgcct tattgaaatt atctatatca acacctgtag
     5941 aatttacgct atttacaacc attgattcca taattacaat ttctccaact atattttgaa
     6001 gtaagtccaa tttttctaaa tttacactca taatactctg cttacttatt ggtaaatgtt
     6061 cattttcttc acttagacta tctttttcca tatcagtttt ttcatttaaa acatcttctt
     6121 gtatctcatc ttctgtatag ttattttgat aacttttact tactttatta ttatctttta
     6181 atttattttc tactgcatca ttgtttgatg tatttttcat ttctatttct tttttactaa
     6241 tatttatgta ttcttttaca tagagattat cttctatagt tttataaact attgccttat
     6301 cctctttagc tacaaattgt atataaaacc cataactttt aatatactct gtagactctg
     6361 catttgtttc tacatctttt ggataaaaat ctataaattc acagtaatct ctaagttcaa
     6421 atacaagcat gaaagctctc acattttcca tcatgcaacc ttgttcaaag attattttta
     6481 ctacatcaga gtcttctttg tattcaaaat ttgaatcgat tacttctttt tcgtctttac
     6541 tttctaaatt tgcattatcc tttgatttca tagaacttga taattccaaa gtactcacat
     6601 actcttcaat tccttcaata aaattagagt aatcagaaga tatacaacct cttgattgta
     6661 actcatctat atctcttctt ataaaatcta atgattgaaa gactaaatca aataataggt
     6721 cattgtctaa aacttctatt ttaccttcac gtatagcata aaacaagtct tctacactat
     6781 gtgctaaagc agatatattg tctaacccca tcatagatgc tgaacctttt atcgtatgca
     6841 ttattctaaa agtttcatta atgttgttat gagtaaatac tttctctttt tctatttgaa
     6901 tcataatttc atctaattgt tcgagtaata aacttgtctc aaatataaac atatctaaca
     6961 tttgtctcat actcggttca atataattca catttatcac ctacgaccta caaataattt
     7021 tctattatat atgcatctca taatttaaat ccttgatgat tctcttatct cactatatgt
     7081 acctcataat ttaaatacac aattattctc ttacttcaat atatatacat ctcataattt
     7141 aaatacatga taattctctt atttcaatat atatacatct cataatttaa atacatgata
     7201 attctcttac ttcaatattc acctcataat ttaaacccat gatgattctc ttacttcact
     7261 ttcctttaga tgaaattttt ctactaattc ttttaaaatt tgagcttgag cagacatctc
     7321 ttctgaggct gctgcacttt cctctgctgt tgctgagttc atttggacta ctatggaaat
     7381 ttgctctatt ccagataaaa tctgtgtaat tgctacttct tgactatgta cagccgaaga
     7441 aataccatta atataattag tagttttttc tacaccattt actaccaagt ccaatgcatt
     7501 tgcagtctct ttagcaattc tgacaccatt ttctactgtt ttaatagctt cttctatgag
     7561 aatagctgta ttttgagctg cttttgcact tttaccagcc aaagacctaa cttcatctgc
     7621 tacaactgca aatcctctac catattgacc tgctcttgct gcttcaacag ctgcatttaa
     7681 tgcaagaata ttagtttgga atgctatctc atctattgtt ttgattattt ttgatatttc
     7741 actcgatttt tcacttattt cacccattga tgtcatcata tcatccatac atctacttcc
     7801 aaaaccaact tgtgatgcag attggtcaga tacctcacat gcaagactag cactatctgc
     7861 acacttctta attccatctg atatctcatt aatcgtggaa gctaattctt ctactgaact
     7921 agcttgttca gtagcaccct gtgaaagagc ttgtgcacct gctgcaactt gttctgaagc
     7981 acttgcaact tgctctgctg ataaatttat ttcagaaaaa tcaccattaa aagagtttat
     8041 tatactttct aaagatattt taattgattt aaaatcacct ataaattctt ggtctatctc
     8101 tactcttaaa tctccttttg caatactagt taatgtactg tctataaggt ctatgtaatt
     8161 taaaagcata ctttgcatct ttttgacaga actcactaat agccctattt cagatttact
     8221 ttcttcaacg tctatacttg ttcttaagtc cccagatgca attcttgaaa agtgtttttc
     8281 tactttatta ataggaatca ctatttttaa ttttattact gtatattcta ttattgtcaa
     8341 tattattaaa agggaaagta taaatattgt tcttaatatt agactttgta attctttttt
     8401 tacctctaca attttggaat ttgaacgggt aactatatcc tcttgaaatt catttattaa
     8461 agaatccatt ttctcttggg agtttatata gtcactacca aaaattatac tttgagcttt
     8521 actcttatca ttactttcga ctgcctttat tgcactttgt tctgttggta ctaaagaatc
     8581 tgatatttct tttgcttcta agattttatt tgactcgctc tttgtaagac caattttttc
     8641 taatttgttt aaagctgatt ctcttgtttt tccgtataat tctttttcat aaatatcttt
     8701 attctttttt tctcctgtaa atacatatct tcttaataca tcacttatct ctctagttgt
     8761 atcttttata tactgacttt gagtcctcaa attattcata tcattaatac ttttttctac
     8821 tttttcaaat gctttataag atgaaataga agaaaaaatc cctgctagaa cagccaatac
     8881 tataataatc agcaatacaa ttgctaattt agaaagcttt acttctcttt tcatatctgt
     8941 actccttcat aaagtaagtt tatatctttt ttaatccttt cattgtactc actacgctac
     9001 aatcttttcc taagttttta ccctcataca ttgctttatc tgctaaggat atgttttctt
     9061 ctaatgatat atttgagttt acttctacta ctcctaatgt aatagtgcac tttattttat
     9121 gttctttata gttgaaatca aactccttta tctctttacg gattctttct gaaagtatct
     9181 tagcaccttc tattggagta tttgtgagca ttatcaaaaa ctcttctcca ccccatcttg
     9241 atacagtatc aatttgtcta caattctttt ttattatact tgatattact gttaacacga
     9301 aatcccctgc ttcatgccca taagtatcat tgataacctt aaagtcatca atatcaccaa
     9361 ggataaggga tattgatgtt tcactatatt tattaattct tctttgctcc ataagctgat
     9421 taattatatg tcgcctattg taaagacctg taagataatc tcttacaacg agtctattca
     9481 atttttcaag agaagattcc agttcattat ttatcttttt taatttatct tgagatttct
     9541 ttacttcaag atgagctata acacgagctt ttaattctgt catactaaaa ggtttcacca
     9601 tatagtcaat tgctcctaca ccaaatcctt ttactatgtc tgtatctgta ttttttgaag
     9661 ttataaaaat tataggtata tctgctgtac gagcattaga ttttacttcc ttacaaaact
     9721 caaaaccaga gttatctggt aaaattatat caagcaaaat aatgtctggt ataaattctt
     9781 caataaattc ttttgcctct attgcattaa atgctttttt aaccttaaaa ttatcttttg
     9841 taagtgtttt atctattaag tcacacatca gaacactatc atcaacgact aaaattgttc
     9901 cctgttgctt atttttcata tacaaacctc tcttaaacat aatatattca aattttaatg
     9961 atttaaaatt tttatactta ataattatac cactatattc ttaaatgttc tcatcacaat
    10021 ctttttataa taacactcca actacatccc tatgttacat gatagtgcaa tcaaacccat
    10081 tgattaattc atctattaaa acttcatctt tatctgtcaa aagtttctct aaatctagta
    10141 aagtaattat tttaccttct aattctccaa ctccacttac aaaataatcc gaatattcta
    10201 tagtaactct tggtggaggt gatattttac ttttttctaa gcttactata tcatcaactc
    10261 tatcaaccac aaatccaact accaagtcct ttatttcagt tactactata tacatgcaat
    10321 ttgtagtcat taattcatct tttttaagtc tcaaacgcat gtctattatc ggaatgattt
    10381 ttcctcttag atttattatg cctttagaat atgtaggtag ttctggaata aatataattt
    10441 cttgatttcc agtaatttct attacctttt caagttcaac cccaaagtct tgctcatcta
    10501 ctctaaactt tagatactta attccttcat caattagtcc ataatctaaa tatgggtcat
    10561 ctggaaatct catttaatac ctccctccta aaatacactt tctatgaaat atatattata
    10621 atttcttctt acctttattt attgaatcta caagtaattc acccgtctca gtgtaaaaac
    10681 gtattgttct accataattc atacctgtgt cctcagctaa tattggaata tttaatccta
    10741 aaagagtttt ttttactgcc tcaacattcc tatgtcctat acttgcaatt actgaattgc
    10801 tacttcctaa aaacatctga gcacctccag caatttttgc ttttatatat attctatttg
    10861 cacctatatt ctccatagat ttaatgagct catttattcc tgtgtcagca aatttacact
    10921 tattttcaat gttaatagca tctttactat atggcaacat aacgtgtaac attccaccaa
    10981 ttccagctac tttatctatc aaacatactc ctacacaaga accaagtgca taagtaacta
    11041 aaacatttgg tctataggct atcttcatat ctgcaatgtt cactactatc tctctattca
    11101 tacttctaat cccaacctca cgagtatttc tctaagtgag ctcatttctg gaatcatcaa
    11161 aatgtgacta gtaaaataat tatcactcat tttaaattta ttttctataa ataagacttt
    11221 gtcaccaaca tctgaaaatc ttatcatagg tacatttaga acagctccaa ccatatcaat
    11281 acatatatct ggaattgaaa cacttatagt catgtttaac atagatgcaa tagcatttac
    11341 atatgaactt gccataatat ttcctatttc cttaattgct gaaatttcaa ttgcctcaat
    11401 ctcatctaaa aaagcttctt ctttattaaa aagagaactt agcataagtt gagttattga
    11461 ttcatccaac aaaaacataa acattccatt gatatcacct ttcatatcga gtaaaataca
    11521 tactactttg ttttctggac caccaagcaa atttgtcgct tcattatatt caagtatctt
    11581 gaccataggt attaatactt ctacattgct atttatcatg gatgcaagtg cagtaattgc
    11641 attcccagag cctatattac caatttctct aagagcatct atatgaacat catcaagttc
    11701 taaataattt ataatataaa cccctccctt tattattgca tttatttgct tttcattgta
    11761 ttagtgtata tttacacttt tattttaaag cattatctac aactttaact aatgtttctg
    11821 ttttgaaggg cttcactata aaatctaacg ctccaagttt tatggcttct acaatcatat
    11881 tctcttgtcc tattgcagag cacattacaa ccttagcact tgaatccaac ttttttattt
    11941 ctcttagcac ctctaaacca tctttttttg gcattgtaat atcaagcaac atcaaatcag
    12001 gcttttcata tttaaatata ttacacgctt cttctccatc atttgcttct attaaattat
    12061 tatagccact tttactcaga gcttctttaa ttatcattct cataaaaata gcatcatcta
    12121 ctatcaaaat tttattttcc ataaaactaa ctcctccata tgtacaacaa taaacgcttt
    12181 tatcttcagt tattgtctat actatctgac tatttttcgc tacacaataa atacatttca
    12241 ttgataaata aaagtaatta tttatgccat attatactta attctcttaa cataatttgt
    12301 caacaaaaaa acttatatat ctattgtaat atatgtttgg cgttttgacg agttattaaa
    12361 aatataattg tataaaacat aaaaagttat caaaagtaat taaattataa taaaacaact
    12421 ttataccttt tttatgtttg tataaaaaaa tttttcagat tcattaaaat catttctgta
    12481 gattcatata ggatttgact ttctcaatat ctaatagata gttgtttatt tacttaatta
    12541 tatttctcta tatgtattat cgattaaatt agatttagct ttatacatta ttttttatat
    12601 ttttcaaatt gtatactcat aaatccagaa gtattctaat gtgtttataa tacttttttt
    12661 catattttaa attaaataac aaatcattat atttacaagt atcatttatc aataaacaat
    12721 attaaatgaa gaatatgtct gaagattcaa agtgatactg ataatattaa ttactaaaaa
    12781 agcagtaaat cttttacaga tttactgctt atagttataa ataataaaac tatctataat
    12841 aaatgtacta tactcaatac ttcattcaat atagtaataa caaatctact ttattcctat
    12901 ataaatatga acttcttgtt tctttgtatc aaaagtatta cattgatact cttcaaaatc
    12961 acttatataa gtcctatcaa aatccatttg ccaaaactca aaccaaaaat ctcctacttc
    13021 tttttgacct cctactataa caaactttgc atacttacct gctggtataa ctttactaat
    13081 aatactttct ccaacagtat tattagtgtt taattcttct aaattcttct ctttatcaga
    13141 attactattt acttcacaac atgcaacaaa gctatacgga cttgtaaaat caccctggta
    13201 atctgtatat agacctattg tcttgtcatt ctttttaccc tttatagcat tatatatccc
    13261 tttgcccata aattttttcc acaattcacc tatatcattt accgcttgtc catctttatt
    13321 tgtagtctcc ttcgatattc ctataactat tttctcattt atctctacta tttcataatt
    13381 catactttat acctcacttt gtttttatta atatatttta ttttgaacta attcaattat
    13441 aatttataat atacgacacc tttatgtcat atttttaata taattaaact cagtgagata
    13501 ttatatacta aatgcaagat attatatatt taataaaatc tttaatctag cattatatta
    13561 taatgaataa attttagaca actcccttag tctagttatt acattatccc taacatcttt
    13621 aggttcaagt acttcaacat tgtcaccaaa tgataaaata tatccataaa tccattcacc
    13681 aataggaaat tctgtaatta catcatatgt atcatcttca tttttagtta ttaaatcctt
    13741 attaaaatca tcaaatactc taaaaagcat cttttcttta aacctcaatt tcaacgttat
    13801 agtattttcc ttaattactt tagaatcatt caaacatact tcttctatta tctttcttga
    13861 aaatacttca tcctttatag ataaattcct tatcctacta attctaaata tcctaaaatc
    13921 atcttttagt ttacaaaatc catacaagta ccaagtctta ctcttataca taagcttcag
    13981 tggttcgaca gttctgtttg tctggcttga caaactattt acataattaa aatttatagt
    14041 attacgcctt aaaatagctt cttttatttt tgtaaattta tcatcttcat taaaattact
    14101 tccccattca gtaaagtcta tttcaatcca gtttgaaaaa ttctgctctc caaatattga
    14161 gccaatttta tttactactg aatttatttc tggatactta gtcgcctgta atgttttcag
    14221 tgccactatt aaactctctt tatctttttt tgacaatata gccttgtcta tagaatattc
    14281 ttctattaaa gatatccctc ctcctttgcc tttcgtcata tatactggta ctcccgacat
    14341 agacagagtt tctatatctc tatatatggt tcttgtagaa acttcaaatc tatctgccaa
    14401 ctctttagct gttactaatt ttttatttaa tagaattact attatttctg ttaatctatt
    14461 tattttcatt cattaccacc tactaaaatt attaaattta tttaatctaa attaatcata
    14521 ctaattttta aataaataaa atcttagaat cttatctaaa ttattcttac atgattttat
    14581 ttactttcta ttatctttct cactttggat attatcatct taatttattt attactatat
    14641 caatttactt attatcatct catttgttat cgtcttactt aatttactta tttctatatc
    14701 aattcactta ttattacctc acttgttatc atcttactta atttacttat ttctatatca
    14761 atttacttat tatcatctca tttgttatcg tcttacttaa tttacttatt gctatgtcaa
    14821 ttcatttatt attatctcac ttgttatcgt cttatttaat ttacttattt ctatatcaat
    14881 tcacttatta tcatcttaat tcatttgatt attatcattt actttattca atttctatat
    14941 caaaaattag tatttgtact taatacttaa aattaattta aagtctttac atattattta
    15001 ttttttattg taatattaat ttccatactt tgctaagcta cttccactca tttattttaa
    15061 aatttcaatt tactatttct caattctata ttattatttt tcaattttat attactaatt
    15121 ttaaagcttt ttagctatta ttcctacaat atttaaacaa ttttttaata ataaagctat
    15181 attacaatat attcaaaata tgtaatattt tagatatttt tcgttgacaa tgttaaattt
    15241 ttgttttatc cttaattaag gacatgttat tgacatttct gaaacttatt tgaaatagtt
    15301 ttttcatttt atttaggaaa acgtattata cctaagaaaa cgtattttct catttcagat
    15361 aagtaaaata tttattcttt tggggaggaa atcatggaaa ttaataaaaa acattttatt
    15421 caagtatttt taacttgctt aatcttggta gtaatatgtg aatttatagg gcaaagaact
    15481 atagctattg gaaaagcctc tatagtactg ttccctatgc tttatgcagt tataattgga
    15541 cttataataa caccagattt attaggtaaa aaaattaaag cacttaaaaa agtggttgga
    15601 gaaaaagaaa taaatattgc tggtgaagtt gttggaattg cactagtaat gcttggtata
    15661 aaatatggta ctacagttgg accaaacatt gacaaaataa ttcaagctgg accagcattt
    15721 atcgctcaag aatttggtca tatacttgca ccaatcgttg cattacctct tgcattaatg
    15781 tttggaatga aaagagaagc tgttggagct actgcaagta taagtcgtga accttcttta
    15841 ggagttatat cagaaaaata tgggataaac tcaccagaag gtagtggtgt acttggtaca
    15901 tatttaatgg gaacagttct tggtactata tactttagtg tactaggttc aatatctatt
    15961 tatagtggtc ttcacccata tgctttggga atggcctgtg gtgttggtag tggaagtatg
    16021 atgacagcag ctgctggttc attatctacc atggtaccac ctgaaatggc agatacaata
    16081 cttgcctatg ctgcaacaag caatatgatg tctagtataa caggaattat attcttagtt
    16141 tttgtatcct taccatttac taattttatg tataagattt tagaacctaa attttcgaga
    16201 aataaaaaaa ctaaagaaat taaatctaca gaaggagagt gctaataaat gtttgctaat
    16261 ttaaatttaa agaaaagttc atatcaatta ttggttatgt ctgttattgg agttataatt
    16321 cttataggac aaagaattag cgttggtaca tctatagtta cagctcttcc tggtatggtg
    16381 atgctaatat tagctgctat ggcagctatg attataaaag atttatttcc taaatcaatc
    16441 tttccagctt ttggatttgc aactataatc ggccttttac ttagtatgcc atatagtcca
    16501 acatctgaag tattcttaac taacactaat aatattaact ttatggctat aactactcca
    16561 ctactagctt ttgcaggaat ttctgttgga aacaaaatag aagctttaaa agaaatgtca
    16621 tggaaaatag ttataatttc acttattgta tttacaacta tattctttgc atgtgcgagt
    16681 atagctcata tagttttaag tattcaaggt aaaatatagg aggaatttat tatgaataaa
    16741 gaacaattaa aatctctagt aataaaaact atagatgaaa atagagaaaa aatattaaaa
    16801 ataggtcaag gaatatacaa aaatccagaa tatggatata aagaatttaa aactacagaa
    16861 gctgtttcaa acttttttga gcaagaatta aatttatctg tagaaaaaaa tatagcagtt
    16921 acaggatgca aagcagatgc aaattctagc aagaaaggtc ctcatatatc tatacttgga
    16981 gaattggatg gtatatcatg taaagaacat aaagatgcta atgaaatagg tgcttctcat
    17041 acttgtggac ataatattca aatagctgga atgttaggtg ctgctgttgg tttagtaaaa
    17101 agtggcgttt tagaacattt agatggtaaa gtatctttta tggctactcc tgctgaagag
    17161 tttattgagt tggaatacag agagcaatta aaaaaagaag gaaaaataac ttattttggt
    17221 ggaaaacaag aattaataaa aagaggttat tttgatgata tagacatatc tatgatgttt
    17281 catgcttctg atttaggaga agataaggct ctagttggtc ctgagagtaa tggatttgtt
    17341 ggaaaaaagg ttaaatttat aggtaaagaa tctcatgctg gttctgctcc acatgatgga
    17401 ataaatgctt taaatgcagc aatgcttgct ataaacaacg tgaatgcact tagagaaact
    17461 tttaaagagt ctgaaagagt tagattccac cctatcatca caaaaggtgg agatatagta
    17521 aatgttgttc ctgctgatgt tcatatggaa tcatatgtta gagctagaac tataaatggt
    17581 atgattgatg ctaatgaaag aataaataag gctttgatgg ctggtggaat ggcagttgga
    17641 gctgatgttg agataactga aattcctgga tatcttccaa tattacgata caaaagtctt
    17701 gataatttat ttaaaaacaa tcttgaagat ttaggtctaa aaggaaaagt tattgatggt
    17761 ggagatttta caggctcttt tgattttgga gatgtgtctc atataatgcc tactcttcac
    17821 cctatgattg gtggtgtaaa aggagctctt catacaagag attttgaaat agttgatgaa
    17881 gatttagctt acataattcc tgctaaagca atggcactta cagttgtaga ccttcttttt
    17941 gataatgcta aggatgctaa agatatatta gataccttta ctccagttat gactaaagaa
    18001 gaatatctaa cattcttaga aaaacacgat aaaactttat aagtctattt ttataatagg
    18061 gtggtatcta ctgtaaaagt tataccactc tttgtttttg taacagtata cttcttttct
    18121 tttagttttt agattaaact aagatatatt atcctcctta aaacttttag agctacgttg
    18181 aaatatcagt agaactatgc tatattcttt ctaattaata taaatttcta ttctaattca
    18241 aggtggtgaa aaaatgttta atgcaggaaa tcgaattata aatacatggt tgtaccctat
    18301 tcaagatggc tttgtcttga ttgatactgg atatgaaaat ggttttaaac atttcaaaaa
    18361 acgaatttct aaattcaaca taaaaatcaa agatattcga tacatatttc taactcatgc
    18421 tcatgatgac catgttggtt ttctaaatca gattctagac gaatctccta atacaaagat
    18481 tgttatgcat gataaagctt tagaaattct atataaaggt caaaactctt ttattggtgg
    18541 ttgtaccagc cgtactgcct ttctcttttg ccaaattatg aaactatttg gaaaaggtga
    18601 gcatagtttt tctccactta aacaagaatt tgaaaaaagg tgtattcttg tgtctgacaa
    18661 gaatcgtaaa gaaattgaaa aagaactaaa tggaaaaatt atagatacac caggacatac
    18721 tgctgattca atttcactac taattgatga aggtgtttta ttttgtggag attctgcaat
    18781 gaatggattt ccaagtactc acaaaattac catatttgca gaaagcaaac tagaatttat
    18841 tcaatcttgg aaaacaatca tcaatacaaa acctaaaatg atttatcctg gacatggaaa
    18901 accatttgaa tacagtaaat tagaacaaaa tctaatctat gtaaataaaa taaatttata
    18961 tcctctacat aattcaaaag atattcacag gtttttgtag aaaatacaaa gtaaatttat
    19021 ttgattaatt aaaaaatcta acactttact acgctactta ttttaataac ttaatcttcc
    19081 actagctttt cataaaattt tgttttaaaa ttaattttaa agcgcatatg ttatttaaat
    19141 acattagata aaattcgtca ttaatctact taaagcatat ttaactaaca ccactcaacc
    19201 agaaaattca gaaaactgca ttgacacagg aaaaagttta ttttatactt tttttaggac
    19261 atattgtgga cacgtcttaa atcgacaaac agaatttaaa ttgtaagatt aaccacaata
    19321 cttatttttt aattatattt ttaaacatta gggaggatat tatgaatgat aacgtagtta
    19381 agaagaaaaa cttttttgac aggacattaa acagaataga aactgttggt aataaactac
    19441 cagacccagt tacaatattt ttagggttat gtgtactttt acttatacta tctagtctag
    19501 ttggttctat gggtatatca gtagttcatc ctggtactgg agaaactata accgctgtaa
    19561 atttattgac tgtagaacag cttcaaattc ttttaggaaa catagtcagc aatttccaag
    19621 ggtttgctcc tttgggtcta gttctagtaa ctatgatagg tgctggtgta tgtgacaaaa
    19681 caggacttat gacagcaaca atcaaagcat cagtaagcaa gattcctgaa acaagagtaa
    19741 ctcttgttgt aatgactata ggtatgcttg ccaatatagc ttcagatgca ggtacaatat
    19801 tatttccacc attagctgca cttgtatatc ttggtgttgg tagacatcca cttataggtt
    19861 tattttctgg atatgcagca gtctgtctag gatttgccgc aaacattatg ataagtgtca
    19921 atgatatact tgctgcaagt tttacagttc cagcagctca aatgattgat tctggatttc
    19981 aagccaatgc aacaatgaac ttatttttta tgatagcatc aacttttgtt ctaatacttt
    20041 tggcaacatg ggtaacagaa aaaattgtag ctcctagatt tggtaaatat gaaggaaatg
    20101 cagaactaga tgttgatgga agtcttagtg atgtagaaaa gaaagggctt aaaaaagctg
    20161 gtataagtat attaatatat gtggctatta tagtagctct tagtgtaatc ggtaaaaaac
    20221 cattcttagc tgacccagaa acaggagatt tactatcaaa caatgctcct cttatgaaag
    20281 gtatggtacc tataatagca ctagcatttt tcatacctgg tgttgtatac ggaaaaacta
    20341 taggtaaaat aaagaaggat aaggatgtag tctctataat ggctagtgca atgagtgata
    20401 tgggtggata tataatacta gcatttgctg cttcacaatt tttgcaatta ttcacaaata
    20461 gtaatttagg tctgatacta gctgtaaagg gcggagaatt tttaaaatca gcaggaataa
    20521 atggaccttt attgttgata ggatttatta tattatcatg ttttataaat ttatttatag
    20581 gtagtgcatc tgcaaagtgg gctattcttg cacctatatt tgtaccaatg tttatgatgg
    20641 ttggatacaa tccagcactt actcagatgg cttatcgtat aggtgattgt ataacaaatc
    20701 cacttagccc attatttccg tacttcccta ttatactagc attcacaaga aaatacgata
    20761 aagatgctgg tatgggtact gtaattgcta atatgatacc atactctata tcattcttaa
    20821 tagtgtggac tatactatta atattgttta tggtatttaa tattccacta ggacctggaa
    20881 tacttccttc atatagcatg taatttattt aaatctttct aaaaggagaa ataatttatg
    20941 ttagataaaa atagacttat aaataatttt atggatatgg ttagaattga tagcccatct
    21001 aatcaagaat tagaaatgtc taagtggttg gtaaactact taaaagaaag aaatatagac
    21061 gccattatag atgatgcagg tgaaaaatat ggtggtaata caggtaatgt cattgcctat
    21121 ataaaaggtg aagaaggaag tagaccactt tgtttatgtg cacacatgga ccaagttcaa
    21181 ccttgtttag gtgtaaaacc aatactagat ggtaatgtag ttagaagtga tggaactact
    21241 acacttggtg cagatgataa agctggaata gctgctatac ttgaagcttt agaacatgtt
    21301 attacagaaa aaataccaca tagagatatt tatctttgtt ttacaatctg tgaggaagcc
    21361 ggtatgcatg gtgtcaaaaa ctttaatcct gacaacttgc cttgtaaaga catggtgatt
    21421 ttagattctg gtggagctat tggttcgata gcatacaaag ctcctgctca acaatctata
    21481 aaaatctctt ttcatggaaa gaaagcacat gctggtatag aacctgaaaa agggttaaat
    21541 gctatattag tagcctctca tgcaataagc aacatgcaca taggcagaat agattcattg
    21601 actacttcaa atataggtaa aatagaaggt ggtggagcta caaacatagt aactgataag
    21661 gttacattga ctgctgaaat taggtctcat atacctgaaa ctttagagta tgagcttaat
    21721 catatggaaa aatgttgtaa ggatgctgca tctaaattta atactactta tacttttgaa
    21781 catagtatgt cttaccctag ttttgaactt agtagagata gtcatgtttt caagttaagt
    21841 gaagaagcaa taagacaagt tggtgttgtt ccaaatccaa tggtaattgg tggtggaagt
    21901 gacgcaaata tattagctaa tcttggatat aattgtgcta tattaagtct aggtatgtat
    21961 gatgtacaca cagttaatga atatgtaaat atagacgaat tatatgatac tgccaaaata
    22021 gtttatcata tgattaaatt ataaatatca taatataact ctttaaatta taaaaataaa
    22081 aacctatgta tcttcaactt tataagttat atattaaagt tgttttacat aggttttagt
    22141 attttatata ataatttgtt ttaacatttt tcataataag cttcaatatt ttgcataata
    22201 atttgttcta gcatttttaa taacaagctt tagtatttta tattaataat ttattctagt
    22261 attttacata atcatttgtt ctaatttttt tcataataag ctttaatact ttatatagta
    22321 atttgttgta gaattttata caatataatg atttatacag ttttataaaa tatcttaaaa
    22381 cagtatttca gtaatatttt ttggtcttcc tccaccaata ctagtctctt ttgcacatat
    22441 tcgacctaaa cctgcattta ctattttatt taatatacgt cttgcacttc tttcacttac
    22501 atttagatac tctgctaact cttttgaatc ataaatctta ctttttctat tctcatttat
    22561 agcaataatt tttgcaactg actcacaact cattccagtc tttttagata tttcgattac
    22621 cttttcatca gatagcatca aagaataatt taattcattt tcggaagcta aaggtcctct
    22681 tatgttttca tcttcatcta ccaaatatat accaatttct tttgaatcta tggagtgtct
    22741 taatgcttta tgtgcattat tttcagcctg atacgcagtt actccagtac caattcctat
    22801 actaagagaa aagcccatgt cttttatctc tctctttaga ttgaatagct tatcataatt
    22861 atactcatta tcagctaccc ctttatgaac aaatacaaca taatcatttc ttccaagtaa
    22921 aaataaggaa ccttgaatac ttcttacata gtttactaca agcttatcca tatctgattt
    22981 ttttatcatg tcagaataat agttatctat cttctcttta taatctatta aactcaatat
    23041 ttcaacagca atttgagaaa atcttgcctt acttagagca tattcactct ttaccttgtc
    23101 ataactttct ttgattaatt gtatagtagc ttgtaaacga aatacaggat agcctctttc
    23161 ttttaattca ttatatactg caccaaaacc agttaacatt atatccgtct tattttcttc
    23221 aaataatttt atatgccatt ctacaagttc agactctcct acttccaaag aaaatggatt
    23281 acaaaataca ctcgttgctt taatatcaaa ttctttaagt gcatcttcca caacatatct
    23341 atcaactaca tctatactga atttatctaa ttttatattt gcacttttta ttgcccaaaa
    23401 tgccttcatt atactcgtcc cacttctcgg tacaaatgaa tgtggcttac ttatctcata
    23461 cttagatttt ataaattcat aaactgcaca tcctgtaaat ataatagcat cacattcgtc
    23521 ttcacattta gaaataactt ctattgtatc tactactttt tctcttacat atattttagt
    23581 ctttaaatca ctgtctatct gttttaaatc atcctttatc ttaaacccag agtctgaagg
    23641 acctataata cccactatca taaacttcgc tcctaatcca taaatattat actttttaaa
    23701 aattatatcc tcactatttt ctacttctat ttaattattt tgaactactc catcctacct
    23761 acatttagaa tggaataatt agcttatttt tgataaagta acttctcaaa atcagaactt
    23821 ggaataggct tacaataata ataaccttga attaccacac aatctaaact cactaaaaat
    23881 tcagcttgtt cttttgtctc tacaccttct gccactacat ccatatctaa atcttttgcc
    23941 atggctatag tgtgctttaa aactattttt tctctgtctg tgattccttc ctcattaaag
    24001 aaaccacaat ctatctttaa tgtatcaata ttaatatttt ttaacatatt taatgaagaa
    24061 tatgctgaac caaagtcatc catatttaaa acaataccat ccattctaag gtcggctatt
    24121 atcttagtaa ataattttat atttttaata aataaacttt ctgtaagctc taattctaaa
    24181 aaagattttg gtatactata tttatttatt aaacttaaaa caatttcttt aaaatgtgga
    24241 ttatgcaaat gtaatcttga tacatttaca gagataggaa ctggctcttc acctaaatct
    24301 atccattttc taatcaaaga acatacttgt tcccatacat acatatctaa tctgataata
    24361 aacccattct tctcaaatag tgaaataaat ttaattggag gtattatacc tttttctgga
    24421 tgaacccatc taaccaatgc ttctgcacca acaattttat ttgcattaag attatactta
    24481 ggttgtaaat atacatggaa ttgcccattt tcaagtgcgt attccatttc cctttccatc
    24541 tgtttttctt caagtgcatc atttcttata gtatcatcat aaaatatata gttgttgata
    24601 ctttgtttct ttactttttt gtgagcatat cctgccattt cacacgcatt tgtaattgga
    24661 atatgattat ccaaaattct ataaacccca aaacatggta ctaacatata ttcaaatttt
    24721 tttctattta agctattttt aatcttataa attactttat gaatatctct atcagagtaa
    24781 ctctcataaa aaatgcaaaa tacatctgca tacatacgac aacatatacc attagaacca
    24841 atgttttttt gaatcaactc tgcaacatat attaaagctt tatctcctcc tctaactcca
    24901 taaatgtcat taattacctt gaacttatct atatccatca ttataattgc ataacgcttg
    24961 tcaggatatc ttttaagcat taaacttatt tgttcacaaa aactttcata attgtatagt
    25021 cctgttaatg tatctttttg gtttttatgt agttgcataa gataatctat attttttata
    25081 gcaactaaaa tatgtgtttg tttctcacct aacttatttt tactactaat ctttaacata
    25141 taaattaatg cccaatagta ctttttatct attcctaaac gtctatactc aaaatttagt
    25201 tctaaatcgt cttgcttgct attattaaga ctatcaagag attttagaag gtggttatca
    25261 ttaaataata ttatatcatc aggatgaatt aaatattttt ttatgtatga aaaagttttt
    25321 tcaagatttt cctttatagg aaaactaaaa atattgctct ctgattgata aattggagta
    25381 attaaattcg tatcaatgca aatagataaa attatatcat atgtattata agctaatttt
    25441 tcataagctt tagaataccc ttttatcatt aaatcatcaa aataaacctt atcaactaac
    25501 tctttatgtt taaataaaat attattcgtc gaatcagcta agtcactaat tactttcatt
    25561 tcattatttc taagtttgtt cttattataa tacctcttct tatcttggta cattctctca
    25621 tcagcaactt taattagctt atgtatatca atattatcgt cactccaaat actgcccact
    25681 gctacactat atatcatctc atccttaaat tcttcactta accaactcac taattcttca
    25741 aatagttgtt ttgatatatc ttcacataat acaacaaact catctcctcc aatacggtaa
    25801 acattataag aatgaaagta tttttttatt attacacatg ctgacacaat agcagaatcg
    25861 ccattagcat gtccaaagtt atcattaata tcttttaacc catttatatc tacaaataca
    25921 actcctatgg atttaacttt tcctttttga aaattatcta tatacttaat atatttattt
    25981 ctattatatg caccagtcaa gaagtcatag tagctcatat aatttaattt attttctact
    26041 tttctttttt tcatctcagt taataaaaaa taagataggg atgtcaaaag agaggtatct
    26101 ccaacagctt tatgtggatt atcaactcca ataaacccta ctactttatc atcttgtttt
    26161 agtgaagatg tcattaaact ttcaattttt tgaggtttta aaatttcata ttctattggc
    26221 tgttcttctt ttatattttc tatatcatca attattacaa aacctttttg ttcgaataat
    26281 aaaaaccaat tctttaattc attaatatca agatttgtta gtgcctgttt ttgttcatca
    26341 acaccttcat tgcaccattc atatgtatta gttacttttg ttctatcttc tgatacttca
    26401 aaaacatatg ctctatcagc tttatgaaat ttaccaatat tggttaatac aagatttaca
    26461 gcatcagaaa aattagattc tgttataaga tgtttaatac atccaactaa taactccttt
    26521 atctctaatt tttctgctat tgacttactt atatcttcct tttctgtaat atcaagagct
    26581 atttctaatc gtgcatgttt gccctcccat ttaattaact tgtcctttaa tataaaatgt
    26641 ctatttgttc gagtattcgt attttcccat atgtaatatt catcttcttt taaaatagag
    26701 tttgtacaaa attcgcaggg agaatctttc ccctgtaatg ctttataaca ttttaaatgg
    26761 gatatatcat taagtcccat tgcctttttc ccaatttcat taatatataa aagttcatat
    26821 gtatctaaag aagaaacata tacaatttca tccaactcat ctattaaatt tattacatcc
    26881 atttatatat atctcctttt attcattttc cagattgaat ttttaaagct tttaaaattt
    26941 tgctatatat ttggcaatga tattatactt ctttatgttt taaaatagta ccttaatgag
    27001 gttctatttt ttagtaaata gaattattat tgtgtcaatc gtacaataga gttttgtaat
    27061 acttaattta atatatttat aattaactat cttattatgt atttacaatt aattctcata
    27121 taaatgacaa atctccacct caattaagta ttccaatcat atatgaggat aatacttcat
    27181 tcatttaaaa atataaaact attatatatt aaaatttctt caataataaa ttatttagat
    27241 tgttactttg atatattata taatatcaca aaggctgata taaaaagaca aaaagggcaa
    27301 tttttttata tcaaaaaaaa tgttaaattg atattatcca tatataaatt gatattatcc
    27361 atataggtgc tatatttaac aattctactt acttccctta cacttattag catatagtta
    27421 ttaagagttt gttgcaaaac aacacttagc acactttaaa aagtgtggtc taataagtaa
    27481 tcaacgaaga agacataata aagcataaaa taggatatac ttttccacgt catcaaaatt
    27541 gaggatttta ttattaatat atgataaaat atgcttaata aattaaattt taatgggaga
    27601 atagttatga aaatatttag tttcttgttg tttgtagtgg gaatatgttt ttgtattgct
    27661 ggatttatgg ggcattcctc agctttttct ggtgcaacat tgagtttttt tgcaactaca
    27721 atgatagctg taagacaagt caaaactaag aaaaaatgaa ataggcaaat cctaacttta
    27781 taagttaata ttacataagt aattagtcta aaattagata ctttttctat tacaaaaata
    27841 catcatccac tttgtattct cttaaaaaaa ataaaatagc tatgtaaatt caagattaga
    27901 tagactaact ctctatccat ttcattgtaa aatatacata gctatttgta ttcgatttaa
    27961 aatacttaga ttttcttaca taacaaataa tttctatctg attattactc atgttcattt
    28021 attaaccact cagcaactaa tcatttagta tctattcatc cgccatacgg taacctaccc
    28081 caacctcagt caaaatatat tctggctgag caggattctt ttcaattttc cttcttatac
    28141 ttgccataaa aactctaagc gactgatttt cactttcata gtaatttccc caaactttat
    28201 ctattataaa cttatgggtt aagactcttc ctgaatactt agacatcaac tcaataatct
    28261 tatattcgat tggagttaaa tgtatttctt caccattaat tgacacaata tgattttcat
    28321 aatctatctt taggttttta acttcaaaag actttggagc atcattattt atattatcct
    28381 gttgagcttt atttctaaga gccacacgta ctctagccaa aagctctgtt acactaaaag
    28441 gtttagttaa ataatcgtct gctcctccat ctaaagcttc caccttatct ctctcatgct
    28501 ctctcgctga aacaacaatt attttattag tctttgcaca tgccctaact cgtcctatta
    28561 cctcaatccc atcaatatct ggtagtccta aatccaaaat tatcaaatct gggtcaagag
    28621 aatgtataag tgatatagct gttcctccat tatctgtctc tacacaccta taattttgag
    28681 tttcaagaga tacttttata aatttacaaa ttggcttatc atcttctaca attagaacta
    28741 atggctttat ttccacttgt ctttcccctc ctcatcatac ataggtatgc taaatctaaa
    28801 tgtagctcct ccagaaggat tattaaaggc gacaatttct ccaccatgag cttctactat
    28861 agatttacat atctccaatc caagaccaat acctcttctt tcaagatttc tagacttatt
    28921 cttagtataa aacctattaa aaatattccc gatatcttca tttggtattc cttttccatt
    28981 atctgcaact tcaaatagta cttgatttga ctcttttttt acagttagtt ctatcttaga
    29041 atttttaggt gtatgcctta tagcattatc aattagattt actaacactt gttctattaa
    29101 taatacatcc acatgaacga ttattatctc atctggaata tttgttttta tgtctctact
    29161 attggcaaac tttttgactc ttaatataga ttcagctatt atttcatcaa caacctctgg
    29221 tcgtttttca atatccaatt ttccttcatc tattctggtc atactaagta tattctcaac
    29281 agaatgagtt agccaactcg tatcttcata tatatttttc aataattcta ctctagtttc
    29341 tttatctatc acatcatcat tttcaagtat tgttgaagat gaacccaata tacttgtaag
    29401 tggagttctt aaatcatgag aaattgacct aagcaagttt cctcttaacc tctctctctc
    29461 tgcctcaagg tttgcttttt tatttttctc aaataaattt tctctatcaa ttgccaacgc
    29521 aacctgtgtt gaaactgctt ctaatagtat cttttcattt tctgtaataa tatctatctt
    29581 aaaacacgca acacctataa caccaagaac atttgattct tgacctttta tagggaaata
    29641 atatgcactg ctgtttttac aatattttgt cccaattcca actgggttac ctgtcctaaa
    29701 agcttctttt atagcttcct tttctaatac tgaatggaat atattctcac ttccatcatt
    29761 gttacaaata taaatacttg gcttacctag attattattc tcatctgcaa tagtcactat
    29821 tacagttcta tttaatatat ttactaaatt agacccacaa aattcaataa tttgattttt
    29881 attttttgct ttaagcaacg ttttgttatt ctcatagagc aatcttatca ttttttctct
    29941 cttatgagaa agtctcactt ctctttttat cctagaagtt aaagtacttg ttataattgc
    30001 tgccattagc ataatacaaa aggtcatagg ataatctttt ctataagcta aaaaagtata
    30061 taatggatgc gtaaagaaaa aattaaatga tagcactcct attactgaag aaagtattcc
    30121 aaaaaaatat ccataggtta tacttgtagc aaatagtaca cctaatatgt atactagtat
    30181 aatattagat tcattaaaac ctaccttttc aaaaactact gatattccag tagcaattgt
    30241 cataaccaat atagttttta tgaagtcctt aataattatc tttttactga gatagccatc
    30301 ttcatcataa tcatactctt ttaagtcttc atgttgtagt cgttcctttt tcatttacta
    30361 caattcctcc ttattgttac tgtttaaatt ggctctattt tatataatac aattttatca
    30421 taataaattc aatcaataca tttaattaat gtacttaaat tactaaaagg tgctgtctta
    30481 aaatgaaaat aaatctctat ttcaaaacag cacctatata tttaaattac taatttagtt
    30541 tttacatact taaatcaata gttttattca atttcataaa ttataatact tcaattataa
    30601 aacatttcta tccaacaagc ataaatataa agtgggcaca tatacctgca cataaaccac
    30661 ctatagtatg cgaaagtatc gctttaccag ccaatggtct tgcatctaaa gcatccatca
    30721 tacctatgtg tgtacttaaa tatccactcc aacacatacc cattgctgtg aatactgcta
    30781 tatcattagg agttatagcg cctgatttta taaactctgg tactaaagat attgctgctc
    30841 caacagctcc taatgcagtt acagggaatg ctattgcctc tggtgatgtg aatccaaata
    30901 atggttctat tatgaagcta atcttatcac caatagcagg taataatttt ataccttcat
    30961 atgcagctcc tgtgtaaaca gcttgacctg tagcagggtc tgtagatggt ccaaaagtta
    31021 ataacataac taatgtacaa actactaaaa ctcctggtat tatagccata cccatttcaa
    31081 cacctaactt accaccttca agtatagcat ccaatgttct ttggaataca ttaccatccc
    31141 ttatttctct aaactcttca agttttgcac ctttatcatt tatttgcttt tcagtatcat
    31201 ttttagggtc ataattataa tactttttag taaaagtcaa cataattcta acactaataa
    31261 tactacctat tattgcccca acattaccta ttatagctgg tagtacatat tctttacctt
    31321 gagctatcat aaaagttgtt acaataagtc ccataccaaa ggctgttcct aaattacata
    31381 aagcaggtac ttgatacttc ttaaaatatt gtgtaaatgt tttgtcttta gcaaatggta
    31441 taatagctgg attatcagat aaatatgttg caactactcc tgctatacta gcaccaggta
    31501 agccccatat aggtctcata agacccttaa atatcttatt aactaaagat attactccaa
    31561 actctgaaag caatgcacta agtgcacctg caagaactgc catagccatt attaaaaata
    31621 ctgtgtctaa taaaagcgca tgtgctgtac tcattattac tttaaacatc attcctgcac
    31681 ccatgatgct tcctacatat ccaaatccta ccgccaatag tacaataaat acgaaggttt
    31741 ccatacttac tgccttgact cttctcttat ccgacagctt ttccatcttg aaatcttccc
    31801 ccttttaatt ttaaattaag gttcctaaca ttggtacaaa ttttttggta caaactgagt
    31861 tctaaaactt acactcgtaa tgcaagttgt cagttttttg aaataaaaaa aaattacgtt
    31921 tatagaataa gaatatcctc tttaatttgg atactcttat tctattttat gttattatat
    31981 tatcatcctt ttgtttaaaa gtcaattttt tctatttttg ttgtttaatt ttatttatac
    32041 tctttttata tttttcattt tcttttatct ttgtaagtac tccatataag ttgacttttc
    32101 taaatacagt agttataaat accaatccta atgcaattga acttgcacac gataatgtac
    32161 tcaccccata ttctacagct tttatataat tattggtcaa aacagaatac atagtattat
    32221 atattccata acctggcact aatattatta aacagcaaac acttaatgta gttgctggag
    32281 tcatataaat tcttgcacat aactcacaat atatcgcaaa acaaactgta gctataaaaa
    32341 aacataagtt ttctgttact cccatattta aaagaaattt atacgaaaac caagctatac
    32401 ttccaccgat tcctgctagt attaagtttt ttcctttcat attaaatagc actccaaagc
    32461 ttaaggcagt aaaaaaagct gctattactt ctataaacaa atgcacttat atccccccta
    32521 acttgaagta caatccaagt accaagaaca ttcctactgc tatagataca cctacaaaaa
    32581 atacttctgc taattttgca agaccagaaa tcaactgtcc atctaacaaa tctcttaatg
    32641 cattagtcaa agcaagcccg ggaactaaga gcattattgc tcctgctatt aaatggtcta
    32701 acgtctttat gaatccgagc tttaaaatta aaattgaaca agaagctata ataactgctc
    32761 caattgcatt tacaaaaaag tcattaaggg aagatttact taaatacata ataacaaact
    32821 tagtcagaat cccaacagta aatgcagcta taaattcttc cacatttcct ccaaataata
    32881 tcgaaaaagt tgctgctgca atacctgcaa aaaatattgt tattaaatcc gagtaatagt
    32941 tatcttcact tatttcatct aaaattttct cacataattc aatatctaaa ttatttatac
    33001 ttattgctct tgataatgag ttaacttcat gaaccaagtt taggtctact cttcttgagc
    33061 ttattctttt aattgctgaa tgtaatttcc catctacaaa tacagatgcc attacagctg
    33121 ttggagttgc aaatacatct acgtggtcta ttccaaaaga ttgacatatt ctagctatcg
    33181 tttcttcaac tctataggtt tctcctccac tttgcaacat agctttacct gcatttgagg
    33241 aaaagtttaa aattctatct atatccacaa aacatatctc ccattctttt atagtattat
    33301 tcatatttta atacaagata ttatttattt aaactatttt aaataattca tatccaacat
    33361 ttacatttta tgaaaaaact tgttttttat gcttgtcaaa atcaaatttt aagcttgttt
    33421 acaccataaa atggctgaat taatatttga caaacacttt caaccattta tataaccttc
    33481 taaattgtat aactttttac tacaaataaa attatatctc ttttaattct ttctcttgag
    33541 tatttagctt atagtaactt catatttata tatgtacaat ataaaacatt atttttatga
    33601 tacaaaatat aatttgtaaa tgtatatatg tattaactgt gtatatataa attattctta
    33661 accttatcag ttttttcata tatcttcatc tataccgacc atatattaat tacattgacc
    33721 atatattaat aaatgatatt acatagactt aagtatatta aaaaacttaa atttagttat
    33781 ttaacaacat aatactctaa tttaatctat aaaaatccat acctaatata atgcaactct
    33841 tattttaaca ccatctatta cacaaaacaa catattaaaa agtaaaatac aaaatatcta
    33901 ctataaacct tattttaata ctgaatatat attataatat atttaatgta gcttaaatat
    33961 agtttaaaca taaagaaagg aaacggtata tgctaagaaa agataaagtt ctattatctc
    34021 tacataaatt atgtgaaaat atgactttaa aagaccttca atcagataaa acaggattca
    34081 ctacaataga aattgctaac cattcatctc ttgatagaag taataccagt aaagaattaa
    34141 ataacctata caatgaaaaa aaagttctga aaatatctgg taagccaatt ttatttctac
    34201 atgctagtat tatagaaaat ttaattggcc gtactttgaa cagtgatgaa ttttctataa
    34261 ataattgtaa tgagctactt aaatcaagta aaaatgactc agaagatatt ttttcaacat
    34321 tacttggaca tgattctagt cttaaactac ctatagaaaa agctaaatct gctatactct
    34381 atcctccaaa aggtcttaat acattactaa taggacctac tggtgttgga aaaagtacat
    34441 ttgctgaaac aatgtacaaa tatgctgtag aaagtaaaat cttttcttct gaaagcaaat
    34501 tcgtagtatt taactgtgct gaatatgcag aaaatgctaa cttattatta agtaatttat
    34561 ttggttatgt caaaggttct tttactggtg ctaataagga taaattcggc atagttgcac
    34621 aggctgatgg aggcatatta ttcttagatg aaatacacag attaccacca gaaggtcaag
    34681 agatgctttt tcttttgatg gacaaaggca tatacagacg attaggagaa tctgacattg
    34741 tgcataaagc taatgtcttt attgtgtgtg ccacaacaga agatatacat tcttctctgc
    34801 ttggaacttt tttaagaaga atccctgtta caatcaacct acctgcttta caggataggt
    34861 ctttaaaaga aagattatct cttattaaat acttctttat tatagaatca aaatacacca
    34921 atgcaactat aaaagttcac aaagatgtaa ttaaatcatt actcctttat gattgttttg
    34981 gtaatatagg tcagcttaaa tctgacatac aacttatgag tgcaagagcc ttcttaaatt
    35041 acaaaactgg acttaaggat aatatagaaa tagatttatc ccttgttcct gattacatct
    35101 atattggtct tttaaaattg aatgaaaatc gtagtaatct aaataaatta tcagaacttg
    35161 attatatgct tttttatgaa tttaatggta ataacttaga agttgaatat acaaaagaac
    35221 tatctaaata caatatagat acatcaaaca atggatttaa atactctaca gagattcctt
    35281 atctggaaaa tgatataagg agtatgttta taaattacat ggaaaagtac tctacaaaat
    35341 tactttcgat atcttcagta actcattctg attatacaag taatgagatt tttaaagtaa
    35401 tcaatccaaa gatttactat gctgttgaac attctttaaa agaggctgaa aaaatatcga
    35461 gaaacaaata cacaaaacaa acttatattg ctctttcaat gcatataagt gcacttatag
    35521 aaaatataaa tcaagacaca tataatccta agtacaattt atataatgat aaaattttct
    35581 tagataaaga tttaaatata gctaaaatag ttttaagtat aattgaaaat gacttacaaa
    35641 catctttacc taaagatgaa gtaaaattta tatccatgtt tctaaatagc atgtatcttg
    35701 aaccaaacaa tcaatctgaa agtataggag tcataatact tgctcatgga aattcaacag
    35761 caagcagtat gtgtgatgta gcaaattcat tgcttggtac aaaccattgt aatgcaattg
    35821 acatgcctct tgatgtaaaa gtaagtacca tacttgataa aactatagag ttggtaaaag
    35881 aatgtgacga aggtaagggt gtacttcttt taacagatat gggctctctt atagcttttg
    35941 gagaacttat ttcagaaaaa acaaaaatca aaactcgctc aattgaaatg gtatctactc
    36001 caatagtttt agaagcagta agaaaaagta cactaccaga aatgactttg gatgaattag
    36061 ctaattcctt aagctcttta aatccatata ttggacgagc agcaatcgat tcaacagaaa
    36121 taaactatcc tgaaaagtca agagagtatg taataataac tacttgtata acaggatatg
    36181 gttcagctat gaaagtagca gactttataa attcttcact taaaaatatt agtaaataca
    36241 atattaattt agttcctcat aatatagaaa gttttaaaat gtataagaat aaatttagta
    36301 atactaaaat tctggcagtt gttggaagtg tagattttaa tgtagctaac acccctttta
    36361 tacacataga ggaactacta aatggatatg gcctagatat gctaaacaaa ataatagaag
    36421 gtacattcaa tgccaatagt attacaaata taaaagaaac aaatctatca tacaacagtt
    36481 taataataaa ctttatgacc caaaacttag agcttttgga ctctgttaaa ttattcaact
    36541 atgtcaattc ttccttattt acaataatag aattaataga tgaaaactta aagagcaaat
    36601 ttaagctagg atatatacta cattgctctt ttatgataga aagatgtttt aaaaatacaa
    36661 cttttccata taataacatt actgaattaa ttagtaaaaa tcatgaacta tatagtttaa
    36721 tacgtgaagc ctttaagcca acagaagctt attttaatat tttgatacca gacgaagaaa
    36781 ttgcttatat aatagacatg attaatgagt atctaaataa ataaaattta tagcacttat
    36841 tttgtgcata ttaattaata tatgaaatgg aggacgagat tttgaaagga aaaataaaac
    36901 agttaacaat acttgcatta atttttatat ttataactcc tgtatttgca tttgcagata
    36961 ctccaccagt accaaattct tcaagagcag cactacttat agaccaggaa actaaaagaa
    37021 tattatttga aaaaaacatt gatgaaaaaa tgccattagc gagtttaagt aaaatgatga
    37081 cctttttatt ggcaatagaa gcagttgata aaaatcaagt taaagagact gatatggtga
    37141 aaatagacaa gtctacagct tcagtaggag gttctacttg taaacttaaa gatggtgatg
    37201 aaatatctct aggtgagctt atgcagggtc taatgctagt atctggaaat gatgctgcta
    37261 tagccatagc taaacatatt ggtaaaactg aaaagaattt tgtaaatatg atgaacaaga
    37321 aagcagaaga aataggaatg attgatacgt attattttaa tccaaatggg cttcctatat
    37381 atactgaccc agaacataaa gaacctccta ttgaaaatat gtcaactgct cacgatatag
    37441 ttacacttgg aaagtatatg tacgaccatt atgaaaatca agttacaaga ataaccacta
    37501 tgcaagtata taatgatact aaaaaggatt ttacacatta taacacaaat cctctgcttg
    37561 tttcagtacc tggtgttgat ggaataaaga caggatatac agataatgct ggatattgcc
    37621 ttgcattttc tatgatggta cctaaagatg ctaaaaacga aagaaatcat agattgatag
    37681 gtgttgtact tggtgatggt aacaagaaaa atagaatttc ttcttccgct actttattga
    37741 aatatggtaa agataatttc cattctaaaa agatagcaca taagggtgat attatagaga
    37801 ctccttgtgt tgatggtatt gatgatttta agataacagt taaggttgat aaagatttgt
    37861 atggtgttgt ttcagataac gaaaatatca atcctaaggt agtgtttaaa aatatgaatt
    37921 atcctatcca taagggagat attgttggtg ttgtaaagta ttataatgac tctggtaaat
    37981 ttgttggaag tgttgatgta aaaagtgaaa gtaatatagg atgtattcct ttgaaggata
    38041 agattaagat taaggttgct aagataaata aaaaacttga gattaaaaat tctgtttgtt
    38101 ttaaagcata gtaaagcata ttattaaaag ggtatgttaa atttataaag actccacttt
    38161 gtggagtctt tttgtttttt acaaaaaatt aaaatagtgg caacaattga ggatgtgagg
    38221 gagagttgcc actattttgt atagggtatt atattatgtt tttaagctag ttttactatc
    38281 ttctatgttt atataataac tcttgtgtgt gaatttaatt gataattaat atgaaaatta
    38341 tgtgaagttt taagttagtt gacttagact attgtaaatt ttttcagaaa aattctgttc
    38401 ataagtctat tagaccaccg aattatttac ctataatatt ccgatcaaaa aatctattct
    38461 tttttaaaag taaggtcatg attattgtac atatataaaa attccgaaaa ttaatctaca
    38521 cactagtaac attaagtata ataaatttat tttagtaaaa ctattaaaat aacctcataa
    38581 gaaactatag attaaatcaa tcaatctaat ctacagtttc ttgattattc cttaatattt
    38641 ataatttaca ttatttgttt attttaaaac tatctgttac aaatctagtc aatgttgaaa
    38701 ataaattcgc tctgaatata gtagatgatg gttctaatgc agttatctca ccttgtactt
    38761 ttgctatatc ttcatatcct gcaaaacttt gaacttctga ttctgtccac cctgctgtct
    38821 ttgcttcttc tattgcatca gttgctgctt ttaatgttac ttttgatgct tctaaattat
    38881 ctgctgttac ttttcctact agttttgtta cttctgctat tttttcttct
//
LOCUS       DAMJVG010000037        38113 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.037, whole genome shotgun sequence.
ACCESSION   DAMJVG010000037 DAMJVG010000000
VERSION     DAMJVG010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 38113)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38113)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38113
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.037"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            32..1144
                     /locus_tag="PC512_001969"
     CDS             32..1144
                     /locus_tag="PC512_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5009 domain-containing protein"
                     /protein_id="HDF2441711.1"
                     /translation="MNSRIKSIDIIRGLSIALMIVCNNPGTWMRMYPQLRHAVWHGVT
                     LADFAFPFFVISLGVTIPISINSKLKNNKSTLSIILSIFKRSILLILFGFFLNYLGNP
                     DLDTVRILGVLQRMGLVYFVTSLAYLLLKKLNVGSTATIITFLCIATFIIVGYYILAK
                     PYGFELEGSLAQLVDLHFFKGHLYKPEFEPDGFLTSIVAISSGMLGCTMGCVLLKENL
                     GEYKKFFKILVMSIILLIGAFIFNQYFPFNKRLWSSSFVLLMAGSYGILLSIFYFICD
                     IKNKSKIFTPIIALGSSPIFTYMCLEILSHVFWNVPKLTNKVDYPTTLVEWTTYELIT
                     PWAGTTWDSLIFSLLYVLFWVIVMSIMYKKKIFIKI"
     gene            1398..3422
                     /locus_tag="PC512_001970"
     CDS             1398..3422
                     /locus_tag="PC512_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF2441712.1"
                     /translation="MKKTTKLLATGMLSVAMVAPNVALAAENTTANTESNSDININLQ
                     RKSVVLGSKSNASVKFKEKLNADSITLNFMCYDMPLEATLNYNEKTDSYEGVINYNKD
                     PEYLNVWELQSIKINGKDEQKVLNKEDLESMGLNLKDYDVTQEFIISDANSTKAVNEY
                     MRKTSAPVKKLAGATRFETAVEISKQGWKDGSSKVVIVNGELAADGITATPLASTYDA
                     PILLANKDDIPESTKAELKRLNPSDVIIIGDDGSVSQKAVSQIKSAVNVNVTRIGGVD
                     RHETSLLIAKEIDKYHDVNKIYIANGYAGEYDALNISSKAGEDQQPIILANKDSVPQG
                     TYNWLSSQGLEEAYYIGGSQSLSSKIIDQISKIAKNGTSKNRVSGADRHETNANVIKT
                     FYPDKELSAMLVAKSDIIVDSITAGPLAAKLKAPILITPKTYVSAYHNTNLSEKTAET
                     VYQIGDGMKDSVINSIASSLSKHNAPTEPDNSGSAAGKTVVIDPGHGGSDSGATSGLN
                     GGAQEKKYTLNTALATTEYLRSKGINVVMTRDTDKTMALGERTALSNTIKPDLFTSIH
                     YNASNGAGNGVEIYYKVKDKNGGTTKTAASNILKRILEKFNMKNRGIKTRTLDNGKDY
                     LYVLRNNNYPAILVECAFIDNKSDMDKLNTAEKVKTMGTQIGIGIEDTVK"
     gene            3642..4328
                     /locus_tag="PC512_001971"
     CDS             3642..4328
                     /locus_tag="PC512_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HDF2441713.1"
                     /translation="MSGYTNDECEIPKIKSYPGADKEIASEIDYSIVKGTVLFDLYQR
                     IMDLVLSIIGLVIGLPLIAIFGILIKIEDKGPITYKQERLGKCGRRFYIYKLRSMRTD
                     AEKFGAQWAEKDDPRITKVGKFIRKTRIDEIPQLFNILKGDMGLIGPRPERPNFTVQF
                     NEEIPGFINRLAIKPGLTGWAQVNGGYEITPEEKLKEDIYYIKNRSILLDFKILFKTV
                     KVVLTGDGAR"
     gene            4423..5478
                     /locus_tag="PC512_001972"
     CDS             4423..5478
                     /locus_tag="PC512_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp7"
                     /protein_id="HDF2441714.1"
                     /translation="MIKKISTILSLVLLISISSTIGVFADANPKRELIEGSIPEISTE
                     LNKRAFKDSKEVILVNEESIVDSISATPLAYAKNAPIVVTKSKNLGRVTRNYLKELGP
                     EKVTIVGGLKAVSKDAERNIEKMGMKVERIRGKDRYDTSLKIAREMYRTVGFDEAFLL
                     SSTTGLENAISVYSYAAKSGMPIIWAKDEGFEEQIDFLKGKNLKKIYALGDSKEFIAE
                     IDSNLKNIEGIKQINKSSTNVDLIKKFYDEKDIKKIYTARLDFGSRSDVNEYISLGVV
                     SAKENMPILICSDNLSRAQDKFLKDSNINDVVEVGYTVGDYSLFKSIFNLTFLSCIVL
                     ILLLLLITFRALRYESK"
     gene            5593..7149
                     /gene="murJ"
                     /locus_tag="PC512_001973"
     CDS             5593..7149
                     /gene="murJ"
                     /locus_tag="PC512_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HDF2441715.1"
                     /translation="MSKTAKAALWIMAATMFSKVLGFLRELVLANFYGTGMYADVFVL
                     TLNIPGLIIAVIGSAVATTYIPMYFETKKRLGDEGALKFTNNVLNICYIMAIVIAIIG
                     LLFTEQFVTVFAAGFRNDPAKFQAAILFTKIMISGVLFLSGSKIFSSFLQVNDSFVIP
                     GLIGIPYNIIIIAAIALSAGKNVWILPAGALLAMASQLLFQLPFAFKKSYKYKPYINL
                     KDESIKELVNLVLPMLVGVAVGQLNIFVDRLLATTLGDGKLSALNYANRLNEFVMALF
                     VTSIITVIYPKLAKMSGKDNKEGFISTIVKSSNCIILVVLPISIGAIILAEPLVRILF
                     QRGKFDALSTDLTSIALRLYSLGLLACGVRDVLYRAFYSLSDTKTPMINGSIALIINI
                     VLNLILIRPLGHAGIAISTSTSNIITVILLFISLKKKNGYFGGDKIIKTGLKSLVASG
                     VMAVATLLIYNNLYAFMGSGTIKEIISVGAGVLGGASVYTVLIVLFKVEEMDLAFEFL
                     RKGKQKLLRR"
     gene            7195..8901
                     /locus_tag="PC512_001974"
     CDS             7195..8901
                     /locus_tag="PC512_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HDF2441716.1"
                     /translation="MDYKNNYEMWLNSPYFDEQTKNELLSIKDDEKEIQDRFYKNLEF
                     GTGGLRGIIGAGTNRINIYTVRRATLGVLNYIMKTQGEEGKQKGIVIAHDSRYMSREF
                     CIEVAKTLSAYGVKAYIFEELKPTPELSFAVRYLKCAMGIVITASHNPKEYNGYKVYD
                     SDGGQICIDMANDIIAEVNKIDDYSTIKSIDFEEALSKNLITILDNEVDDEFIKAVKK
                     QVLRQNIIDEYGKKLKIIYTPIHGTGNKPVRKVLNECGFENVMVVKEQELPDSNFSTV
                     KYPNPEEKSVFNIAIEMAKNNGTDLIIGTDPDCDRVGIVVKDSSGEYVVLNGNQVGSL
                     LVRYILESLVEENKLPKNNPTIIKTIVTSELGAKIAKAYNVDCLNTLTGFKFIGEKIK
                     AFEESNDRSFIMGYEESYGYLIGTHARDKDGVVSSLMICEMAAYYSSKGMNLYEALID
                     TYNKFGYYKEDLKSVTLKGIDGIKKIKEMMLYFRSVKIDNVADVKVDKILDYKDGVDD
                     LPKSDVLKFLLEDGSWIAIRPSGTEPKIKFYFGANSDNQEDVEFKLNNLISYILNVVD
                     SI"
     gene            8923..9996
                     /locus_tag="PC512_001975"
     CDS             8923..9996
                     /locus_tag="PC512_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate guanylyltransferase"
                     /protein_id="HDF2441717.1"
                     /translation="MKVYNVIMAGGGGTRFWPLSRQEVPKQLINLSGEDALINETINR
                     IDSLAKKDDLFIVTNEKQLEALKDIVKDKCLDSNILPEPCARNTAAAIGFAAFNIMKK
                     YGDGVMCVYPADHYIKDEKEFKSILEKAIYIAENNDKLVTIGITPTFPSTGYGYINFN
                     RENTIEDVAYEVVEFVEKPNYEIAKEYVNSKKYVWNSGMFVWKVSKILEDFKRYLPKV
                     YEKLEDISKYLGTKEEMEKIKEIYPTIQSISIDYGIMERSNDVIVVPGDFGWNDVGSW
                     DSLGAIYPTDDEGNIKRGENITIDTKNSIIYSDDKLISTIGISDLIVVSTNDAVMVCR
                     KDKAQDVKKIVEQLKEEDRQEYM"
     gene            10008..10730
                     /locus_tag="PC512_001976"
     CDS             10008..10730
                     /locus_tag="PC512_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDF2441718.1"
                     /translation="MIPKKIHYVWFGGPKGNIENICINSWKEKLPEYEIVEWNEKNFD
                     IEKEIKGNKFLEECYKRKLWAFISDYTRIKVLYEQGGVYMDTDMQILKDITPLLENNR
                     LVCGYEDDREYINGAIIGVEKGHPFLKDLLEYYEKEVLTSSLFTIPKIMTHLMEKNYK
                     KIDPNNYEEGIRVYDKEYFYPFGFKEDFTPECITENTFGIHWWGKSWAKKRNYFLESK
                     HLTGVNKIWKCCKIFASNTLRS"
     gene            10746..11903
                     /locus_tag="PC512_001977"
     CDS             10746..11903
                     /locus_tag="PC512_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide polymerase"
                     /protein_id="HDF2441719.1"
                     /translation="MKTLNDDRNIMIRKYLYIFVLFIILLRKYMISFIDPNMDIGMIK
                     SALFYSSIGILMLLFLFDKRKSITEMVLVGVCVLLYLLNREGAILLIVLLAVSAKQID
                     DKFIVKNYLIISACFLMVAILLFNLFPSLIFNQEVHYRYIEKIDMLVTRMDFGLGNPN
                     SVFYHMVTIYAAYIFLRYKDYNKWDRILLFGSAFFVYQTTYSRTGFFTILAGLIFVEI
                     IRWIDIKKIKGLPMLLKTLPVILTLFSVIIGTVFDKSTLLNRLLASRPKFWNVYLAEK
                     GNFLKPFGNSYSPAIKATNPLDSSYVYIISVLGVVACILFMYLMYKGIESFIEKDKKA
                     YLVALFIFLLYSFAENLLLEASFSFAVVLLIKEVILNDKREIDLWKMKSRR"
     gene            11906..12745
                     /locus_tag="PC512_001978"
     CDS             11906..12745
                     /locus_tag="PC512_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDF2441720.1"
                     /translation="MLISLIMPTLNRYDDIYLLMDSLENQTYKNFELIVVDQNDNSKV
                     KEIVDKYIDKLDIKYIKSSKKGLSYNRNVGIDNAVGQIIGFPDDDCVYENDTLEKVIN
                     FFNKNKDYKIYSCKTMDSNKVDAFKKMYDGTCDITSSNVLDTITSITFFIDFEGKDYT
                     RFDEKLGVGGEFGAGEEIDYVLNLLSLGFKGKYFGNDIIYHPAKKHSKSKEKYQKDYN
                     YGRGFGALCKKEIVYRKNYKFAKVMVSKLVRNIGGLILSSNRDYHSATIKGRINGFRQ
                     YKL"
     gene            12760..13935
                     /locus_tag="PC512_001979"
     CDS             12760..13935
                     /locus_tag="PC512_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HDF2441721.1"
                     /translation="MDKVKFLINMLLAFFIYPFNKHKFNGRDIWLIGGHSGDIYNDNS
                     KFFYEYMLKEHNDVETYWVVNKDSKVFDKIPGKKLIRGSVENYLYYYNSKAIVFSHAP
                     SADIAPYNFAVPVLNYFHKKTIKVFLNHGTISFKKRKPMNKKFKNIIDNLYKSYNIVT
                     ASSEFERNVMVNDWGMLDDSVYIIGNARYDNLPTNEVAQTRDILYTPTWRDWIKFSSG
                     KFTDTDYFKNIMNFLNDDKLNKILDEKDINVKIYMHHLMHEFIDDIKENITGKRIVFL
                     DKGVTLANEIRKSAANITDYSSVAIDFLYMNRPILFYQFDLDEYMEKVDSYIDLKSEM
                     FGSLAYNNDEAVNKLIDIIENNFEVMDNQKNERNKFFRYNDNKNCKRIYDCVLSKIK"
     gene            13964..14713
                     /locus_tag="PC512_001980"
     CDS             13964..14713
                     /locus_tag="PC512_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDF2441722.1"
                     /translation="MKKNLVSIITPMYNSEKFIEATIKSVLNQTYQEWEMLIIDDCST
                     DNSPNIVKSYMQQDSRIKCIKTETNKGVSNARNLALSKATGQFIAFLDSDDQWNSSKL
                     EKQVNFMLENDYVISFTSYELMDENDKKLNKVIKVPPNVDYRRLLKGNILGCLTVVID
                     KSKLDFEIRMSGVRHEDYVLWLSILKKGHIAHGINEVLALYRKSSNSLSGNKIKAAMW
                     TWNIYRNIEKIPLYKAIYYFINYGINGIKKS"
     gene            14735..15643
                     /locus_tag="PC512_001981"
     CDS             14735..15643
                     /locus_tag="PC512_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDF2441723.1"
                     /translation="MYKYKFTVFTPTYNRAHLLENLYNDLKAQTYDFNDFEWLIVDDG
                     SSDSTKELVEKFISENKLNIRYIYKENGGKHTAINLGVKNADGELFFIVDSDDGLIKD
                     SLEIANDEWDSLENKEGFSGVVGLCVYPSGDLIGTEMPEDKKICHFADLYFKYGVKGD
                     KSIVFVTDELIKFPFPERKEVRFLPESVVWNEMSKYYKVICVNKPMIIRDYLDDGLTK
                     NILSKNALRGRALEFLYLINQNTYPLSRYPYMWIKNYINLARYSLLSDSHYFGELRKV
                     SDKLLYLALFPLGYYKYIGQRKLVSK"
     gene            15691..16443
                     /locus_tag="PC512_001982"
     CDS             15691..16443
                     /locus_tag="PC512_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDF2441724.1"
                     /translation="MNEPLVSIITPVYNSEEFLSETIKSIQNQTYKNWQLLLVDDCSK
                     DNSSEIIKSFRKEDARIKYIKLEKNSGAAVSRNVGIKNAEGRFIAFVDSDDLWDSRKL
                     EIQIEYMLKENVGFSFTSYRYMRQDGSKTNKVARAPKKIDYEGLLRNTIIGCSTVVID
                     KEIVGEFSMPLVRRGQDTATWLQLLKKEKYAYGIQEDLVNYRLVGNSISSNKIKALKR
                     TWNTYRNVENLSLPKSLYVFCFYVFNAIKKRV"
     gene            16421..17764
                     /locus_tag="PC512_001983"
     CDS             16421..17764
                     /locus_tag="PC512_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose/GDP-mannose dehydrogenase family
                     protein"
                     /protein_id="HDF2441725.1"
                     /translation="MPLKKEYKFYILGGKKMKIAIAGTGYVGLVTGVCLAEVGNENVV
                     CVDVDEQKVKSMKLGIAPIYEEGLEELMVKNYNRGRIDYTTDYKKAYEDVDVILIAVG
                     TPERSDGSANLDYIKVVAKQIAETVTKDTLVVIKSTVPIGTNEEIEDYINRNLKNDVK
                     VELASNPEFLSQGTAVKDTLHASRIVIGVESEWAREILEEIYKPFNQPIIVTNRNSAE
                     MIKYASNNFLALKISFMNDIANLCEIAGANIEDVALGMSYDDRIGSKFLKAGIGYGGS
                     CFPKDTKALHWLSEHNGYELKTVKAAIEVNESQKLKLVRKASKLVESFQDMKVAVLGL
                     TFKPDTDDIREAPSIPNIKYLLERGARVTVYDPIGVNNTKKIFGDSILYADSVDDAIE
                     DAEICFIMTEWKDVLNYDIHKYKEKMKNPLVLDGRNCYKIKDMEELGIEYYSIGR"
     gene            17770..18861
                     /locus_tag="PC512_001984"
     CDS             17770..18861
                     /locus_tag="PC512_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDF2441726.1"
                     /translation="MKTVCYLADGSNPHTLKWCSFFKNKGYDIHVISLNGGHMEGIKI
                     YNFGSNVEELKNENISKKTGYLGSIKQIKKLVNEIKPDILHAQYASSYGFIGSLLGYH
                     PYIISVWGTDIYDFPNNGFIQKQIIKHNFRKADYIFSNSRDMAKEANKYTAKHVDVTF
                     FGVDMDRFKPMEVEKEDAFVIGIIKSLEKKYGIEYLIQAFKMLKDEYKDKKIILKIGG
                     SGSQMDNLINLAKELGIENDVQFLGRISPENVSKTFNSFDVTVFPSLREGFGVAAIES
                     EACEVPVIVTNVGGHPESVWENETGLIVEPKQPEEIKNAIIKLMENDELRLNMGKKGR
                     QFVRENYEVNLNFNDIEKIYDSIFDKYKK"
     gene            18945..20858
                     /locus_tag="PC512_001985"
     CDS             18945..20858
                     /locus_tag="PC512_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HDF2441727.1"
                     /translation="MRESIDLEKESFFNRLFKKYKFRHLTLLILDICSVLVAFRMSLS
                     LTGNLNAFTTNDIIISVCIYIVLHIVSFRLFKCYNTLWRYAGEEEIISIFVATLAYLI
                     PIYIINKLLGFDYPIMFYVLNTIFIIMFTSGARIAYRAIRIVMNKTYSRGKVSNILII
                     GAGDAGEMVIQELKRNPELKKVAVAIIDDDKNKIGRIIHNVKIVGTTSDIKDVVEKHN
                     VDEIIFSIANIEKRRKKEIIDVCKNTNCKIKTIPGIYEIIDGKVDIKQIREVEIEDLL
                     GREPIKTNLREISNYIEGKVILITGGGGSIGSELCRQIAGFNPKELIIVDNYENNAYS
                     IQQELLRKYKNKLDLKTVIASIREEKRMDEIFNKYKPEVVFHAAAHKHVPLMESSPGE
                     AIKNNIFGTLNIAGLSSKYRAKKFVLISTDKAVNPTNIMGATKRAAEMIIQTMNAESQ
                     TEFVAVRFGNVLGSNGSVIPLFKKQIEDGGPVTVTHPDIIRYFMTIPEAVGLVIQAGA
                     MAKGGEIFVLDMGEPVRILDLAKNLIKFSGFEPDVDIKIEFSGLRPGEKLYEELLMSE
                     EGLLDTEHKKIFIGRPIDVDREKITKYLKLLREITNNEEVEKIDGIMRELVPTYIKPE
                     DANIKEIATTREK"
     gene            21057..21764
                     /locus_tag="PC512_001986"
     CDS             21057..21764
                     /locus_tag="PC512_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HDF2441728.1"
                     /translation="MMNIKNKKHILKKFIAMVLIAGVVTVEAGAITASAAEPTNSPMS
                     ATVDQCDFLNVRSGASANDAVVGKINTGDKVEVLELHSNGWIKIKSVDNVTGWVNGDY
                     LTIQGGNVDAKVQNVLNLAFKQQGKPYRWGATGPNAFDCSGFTSYVYKNGAGVNLPRV
                     SRSQATVGKKVSRAELKPGDLVFFGSGGSINHVGLYVGDSKFIHSPQTGDVVKVTSMA
                     PGTNYARRLITATRVLQ"
     gene            22066..24177
                     /locus_tag="PC512_001987"
     CDS             22066..24177
                     /locus_tag="PC512_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding glycosyl-hydrolase Cwp19"
                     /protein_id="HDF2441729.1"
                     /translation="MKKISILVLSLIMTLTMCSVSSFADSSNDKEMRAAWISTVYNLD
                     WPKTKNNEAKQKKEYTDLLDKLKSVGINTAVVQVRPKSDALYKSNINPWSEYLTGTQG
                     KDPGYDPLPFLIEEAHKRGMEFHAWFNPYRITMADESIDKLPANHPAKKNPSWVVKHG
                     NKYYYDPGLPEVRKYIVDSIAEVVQNYDIDGVHFDDYFYPGVSFNDTATYQKYGKGQN
                     KDDWRRENVNTLLRDVKASIKSIKPNVVFGVSPAGIWRNKSSDPTGSDTSGNESYVGT
                     YADTRAWIKQGLIDYVVPQLYWPIGLKAADYSKLVAWWANEVKGTNVDLYIGQGIYKQ
                     GQSSYGGQNIAKEIVQQVTLNRKYSEIKGSMYFSAKDIANSTSIQKDLKSLYSSSEEP
                     VTPPSNVKVEKLRGDERYDTAVAISKKGWATNSDTVVLVNGYSIVDGITSTPLATSND
                     APILLVNKDNIPTSTKNELKRLNPSKVILIGGNNSIGDKVESEIKDTLSNVSINRVGG
                     SDRYSTSLMIAKELVKTNPVEKLYITSGTGEADSLSIASKAGEEKQPIVLVSKDNVSD
                     EVYNWISDLKVKDAYFIGGNLSISDSVINKLDKVITNDVSKNRIAGENREETNGKVIQ
                     KFYPNAEYSSMFVSKSNQLVDALTSGPLAAKLKSPVVMLGNSVTSAQKTALEPKKTTL
                     VYEAGDGINQNTLNTFLNLVK"
     gene            complement(24375..25340)
                     /locus_tag="PC512_001988"
     CDS             complement(24375..25340)
                     /locus_tag="PC512_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HDF2441730.1"
                     /translation="MSKLKKFVILLAFLVVIFPISVYGYFYYKLSAIHDSSISSDLLD
                     NNDHKNEDGIINILLMGTDARPNEDSSRSDAMMILTIDNKHNDIKLTSLARDSYVDIP
                     GHGKQKLTHAYAYGQADLLIQTIEENFNIDIQNYACVNFESFMYIIDAIGGVEVTVEK
                     GEIRELNKFIPETYKWSKSDDKGSIQYIRNSGKQTLNGYQALSFARIRHNDTAFARDG
                     RQRQIIQAIIKKTETLPVTKYPGLLDAVLPYVKTNMKPNAILSLGAQVLKMGDLNIKQ
                     FEFPIDDEIHSTGGIYGKAGWVLRFDPDTLDILHDFIFNDIEFKQ"
     gene            complement(25625..26581)
                     /locus_tag="PC512_001989"
     CDS             complement(25625..26581)
                     /locus_tag="PC512_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HDF2441731.1"
                     /translation="MSGLKKFVIFLALLVIAFPVSIYGYVFTKLKTIQDDSINTEALS
                     SNDYKNEENITNILLLGTDARPGEEVSRSDAMMILTIDNKNKSLKLTSLNRDTYVNIP
                     GHGEQKLTHAYVYGQANLLIETIEENFQLDIQNYAVVDFFSFMDIVDALGGVTVTVDK
                     SEIRELNKFIPETYKWNKNDNKGSLKYIRNSGEQKLNGYQTLAFSRIRKNDSTDERDR
                     RQRSVIQSLINGVKDLPVTKYPNLVNTILPYVKTNMNPNEIISLGKELLSIGNLNLKS
                     MEFPLSTENGRKIGNAGYVIPFEEYELDAMHDFIFKDIMVED"
     gene            26949..27737
                     /locus_tag="PC512_001990"
     CDS             26949..27737
                     /locus_tag="PC512_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDF2441732.1"
                     /translation="MIKLIATDLDGTLLDEKSEINPEFYKVFKKLRERGIMFSAASGR
                     QYQNLIKKFEDIKDDMMFISENGTLVVYKGKEILSNPLNKELVNEIIETTRSIKGKKI
                     VMSGKKYAYIESKDEAFIQEVSTYYAKFKIVEDLTKVEGDILKIAVFDFKGAEHNNNI
                     YFEKFSDRAQVCISGVEWLDLTAKGANKGSAIKKVQKMLDIKYEETMVFGDQLNDVEM
                     MKSAYHSYAMENANEHLKQIARFRAKRNTENGVVDKIKEVIKIG"
     gene            complement(27860..28330)
                     /locus_tag="PC512_001991"
     CDS             complement(27860..28330)
                     /locus_tag="PC512_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4358 domain-containing protein"
                     /protein_id="HDF2441733.1"
                     /translation="MKKILILFFSIILSLGMVSCSSSGDYKNVSTSKIKKALKSSDLL
                     IKESKIFDAKDFNYFNDVEEDIIQGFVINSSEKLSLEDIIVIKTDEVDKIYKTLENYK
                     KDMIQAPFGEGHGEKINSEIANNTIIEKAGRYVYLISAENATQIENKILNIIKK"
     gene            28469..29113
                     /gene="uppS"
                     /locus_tag="PC512_001992"
     CDS             28469..29113
                     /gene="uppS"
                     /locus_tag="PC512_001992"
                     /EC_number="2.5.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="di-trans,poly-cis-decaprenylcistransferase"
                     /protein_id="HDF2441734.1"
                     /translation="MRIPKHVGIIPDGNRRWASQNGMTKDKGYESGIDPGLESYRLCR
                     DLGCEEVTFYGFTTDNTRRPSVQTKAFTKACIDAANILIDEGAALLVVGNTKSPMFPE
                     ELLPYTNRIKAKEGQIKANLLVNYGWYWDLNNISGVENVNKNNIQDYIQSFDVSRLDL
                     IIRWGGRRRLSGFLPVQSIYADFYVIDNYWPDFKSDDIKDAFSWYDTQDVTLGG"
     gene            29156..30061
                     /locus_tag="PC512_001993"
     CDS             29156..30061
                     /locus_tag="PC512_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF2441735.1"
                     /translation="MKKKLLDGKITLIICKSVKIYTKKGEEMSKGNNNNNSRNKSKKT
                     SHLNRKKRKLNKKKLAVLICFTVLFLFIAFKATQGVVALVKSMDKSNKTSQQQNVNSE
                     QFDLGNEEENKKKKYTVFIDPGHGGNDKGTESKTSNRYEKDLNLQIAKKLANKLSKQK
                     DIQVVVSRTDDTYISLKDRAILANNSSADVLVSIHLNAEKNGNTATGIETWYRNKATD
                     GSKELAQTVQSTIVSYVKVRDRGIVENNFEVLRESNMPAILIECGFLTTPSEEQKIIN
                     EKYQDQLAEGIVQGVLSYLDSKGNK"
     gene            30376..31923
                     /locus_tag="PC512_001994"
     CDS             30376..31923
                     /locus_tag="PC512_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF2441736.1"
                     /translation="MNKNSMTRIYSLNKIIFIIIGILGIVLLTRHIEVDIKVLILILL
                     TLFSINVFISYLKIKLYEDKINLGLINNSDKFINITKDENFLKHVQNYIISNEKENCV
                     MACFDLCRLKLINDIYGYELGDEVLNNILSNLKNYFGKEAIYGKLKSDVFVLIIKLEN
                     REQKIPYLVNLIKNKIVILSQIDSFKMDINIEASIGIYKFNNNEIDIKKAIDNADMAR
                     LKSKGLKHIEYVEFDNAMEEEIQSIMKIERDLFLAIKNKEFVIHYQPKVDSSTGNIIG
                     SEALIRWLHPSLGMVGPNKFIPIAEKNGLINNIGRWLIQEVFITINKWISEGINVLPV
                     SINLSRVELYKNDLVDFFKLMFNTYNIPKELIELEITETTALRDVKFISERLYEIKSL
                     GMNISLDDFGVGNSNFINLKGIPLDIIKIDRSLILDIVTNTKTKFMVKAIVNLSHDLN
                     VTVICEGVEDMHQVKVLSELGCNFIQGYVFFKPLDEMNYKKLLTDGSYINLKDTLLDK
                     CMTVEEE"
     gene            31926..32324
                     /locus_tag="PC512_001995"
     CDS             31926..32324
                     /locus_tag="PC512_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HDF2441737.1"
                     /translation="MISEDVDYSIRIIRAIFNNGEDKPIDAKMILKSEDIPILTLYRL
                     LRKLCANNILTFNKEDGKTYMLNVSLDTISLRTIVEVIDGKIYINKCTRYVSNCSNCL
                     KGCKVNRELLEIEKEIYKLLSRKSIRQILE"
     gene            32364..34097
                     /locus_tag="PC512_001996"
     CDS             32364..34097
                     /locus_tag="PC512_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HDF2441738.1"
                     /translation="MDDISQDNFLLSKEYENSLDVDTKKASGIYYTPKIIVDYIVKKT
                     LKNHDIIKNPYPRILDISCGCGNFLLEVYDILYDLFEENIYELKKKYDENYWTVDNIH
                     RHILNYCIYGADIDEKAISILKDSLTNKKVVNDLDESDIKINLFCCDSLKKKWRYKFD
                     YIVGNPPYIGHKKLEKKYKKFLLEKYSEVYKDKADLYFCFYKKIIDILKQGGIGSVIT
                     PRYFLESLSGKDLREYIKSNVNVQEIVDFLGANIFKNIGVSSCILTFDKKKTKETYID
                     VFKIKNEDICINKFETLEELLKSSKFEHFNINQRLLSDEWILVNKDDETFYNKIQEKC
                     KYSLEDIAISFQGIITGCDKAFILSKDDVKLNLVDDKFLKCWIKSKNINKYIVDKSEY
                     RLIYSNDIDNENTNKRILDEIIGLYKTKLENRRECKSGIRKWYELQWGREKLFFERKK
                     IMYPYKSNENRFAIDYDNNFSSADVYSFFIKEEYLDKFSYEYLVGILNSSVYDKYFKI
                     TAKKMSKNIYDYYPNKVMKIRIFRDNNYEEIENLSKQIISILLNKSIDKGKVEKLQIK
                     MDNLIMDSLGI"
     gene            34329..35540
                     /locus_tag="PC512_001997"
     CDS             34329..35540
                     /locus_tag="PC512_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HDF2441739.1"
                     /translation="MKGLVLEGGGTKGAYQIGAYKALRELGIEFQGVTGTSIGALNGA
                     YIIQNDIEVMEDIWLNYDYTHFMNIDRETYERFKNVDFTTKNLNAVFELINKARKNEG
                     IDISPLRQLMETTLNEDIIRKSKKDFGLVTVWWDKKINPYPLYIEDIPKGRLIDYLIA
                     SSSLPIFQTNMMDDKLYLDGMFCDNMPIGLLEDKGYEDVVVIRLIDDFIGKMNLNRHQ
                     NINIKTIIPSEYLGGSLNKDRDNVEKNIRLGYLDTMKAYERCTGIKYYFDVEYKYNEE
                     YCFDKFRSMSNETIQYICNLLNIKRDASLRTVMESVIPKLGEVLGLPKDFSYKDLFYC
                     IYEKKLEENNINRIKLYDFNKVIDVVNTNIDSNRNLASNFEVRPKISIKKNKNTKLLT
                     NCIIKDIKNQS"
     gene            35733..35993
                     /locus_tag="PC512_001998"
     CDS             35733..35993
                     /locus_tag="PC512_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr family phosphocarrier protein"
                     /protein_id="HDF2441740.1"
                     /translation="MEKVVSIKNASGLHARPAGMFVKKAAEFKSTVEVVAKDKTVNAK
                     SIMGIMSLGLAQGEELKLVVNGEDEEVALAAMVELVESGFGE"
     gene            36347..38059
                     /gene="ptsP"
                     /locus_tag="PC512_001999"
     CDS             36347..38059
                     /gene="ptsP"
                     /locus_tag="PC512_001999"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HDF2441741.1"
                     /translation="MAYKGIGASPGVALGKALVVEHSELVIEKKSIDNVEAEIAKLED
                     AVAVSKEELVKVKEKASEELGAEEAEIFEAHLLVLEDPELIGSAIDKIKTESVNAEYA
                     LNEIKEMFVSMFESMDNEYMKERAADIKDVTNRILRHILGIKVVDLSALSEEVVLIAH
                     DLTPSDTATMNKKMVLGFLTDIGGRTSHTAIMSRTLEIAAIVGLNDITSKVKDGDFVV
                     FNGDTGEVIVNPDEETINKYTELKAKYEDERKALQLLKGKPSVTLDGKHVELAGNIGT
                     PNDIEGLIKNDAEGVGLYRTEFLYMDRDSFPTEEIQYEAYKAVLEGMDGKPIVIRTLD
                     IGGDKELSYLSMEPEMNPFLGYRAIRLCLDRKDIFKTQLRALYRASVHGRLRIMFPMI
                     SSLEELLQAKEVVKEVLAELDSEGVAYAKDVEIGMMIEVPSAAVISDVLAKHVDFFSI
                     GTNDLIQYTCAVDRMNQKISYLYNQFNPAVLRLIKTVIDNAHKEGKWAGMCGESAGDQ
                     KMIPILLGMGLDEFSMSPISILPARKLITSVKESDMKKLADDVLNMGTAEEIKSYIEK
                     TFNI"
BASE COUNT        15246 a         3988 c         6745 g        12134 t
ORIGIN      
        1 aatttcaaat aatgctgtag attctaaact tatgaatagt aggattaaat caatagatat
       61 aataagaggg ctatcaatag ccctcatgat agtctgcaat aatcctggga cttggatgag
      121 aatgtatcct caattaagac atgctgtatg gcatggtgta acacttgcag attttgcatt
      181 tccttttttt gttatatctt taggtgttac aattccaata tcaataaata gtaaactaaa
      241 aaataataaa tccacactga gtataatact tagtatattc aagagaagta tcttattgat
      301 attatttgga tttttcttaa attacctagg aaatcctgat ttagatactg taagaatact
      361 tggagtactt caacgtatgg gattagtcta ttttgtgact agtttagcat atttactgct
      421 aaaaaaatta aatgttggaa gtactgctac aataattact tttctatgta tagctacatt
      481 tataatagtt gggtactaca tcttagcaaa accttatgga tttgagctag aaggttctct
      541 tgcacagtta gtggatttac atttcttcaa aggacatttg tacaagccgg aatttgaacc
      601 agatggtttt ttaactagta tagtagcaat ttcttcaggt atgttgggat gcactatggg
      661 atgtgtactt ttaaaagaaa acctaggaga atataaaaaa ttctttaaaa tactggttat
      721 gagcataatc ctgctaatag gtgcttttat ctttaatcag tattttccat ttaataaaag
      781 attatggtct agctcatttg tacttttaat ggctggcagt tatggtatat tactgtcaat
      841 attttatttt atatgcgaca tcaaaaataa aagtaaaata tttaccccaa taatagcact
      901 tggaagtagc cccattttta catatatgtg ccttgagata ttgagtcatg ttttttggaa
      961 tgttccaaaa cttacgaaca aagtcgatta tccaactacc ttggtagagt ggactacata
     1021 tgaacttata acaccttggg caggtacaac ttgggattct cttatatttt ctttattgta
     1081 tgtcctattc tgggttatag taatgtctat aatgtacaag aaaaaaatat ttattaaaat
     1141 ttagtgcaat atttttagat gataaagtct ttgatttgtt caaatataca gaaactatca
     1201 aatataatca aaatttctcc tcgataaaat ttaaaaacca tgccataaaa gattacaaaa
     1261 agtttacaat ttgtaatttt ttgtgctata atgaaaaaag atttacataa tattgaattt
     1321 atgtaatata aaacaagctt aagatgtatt aaaaaagatt taaagattta aagaaccaaa
     1381 aaattagggg ggatatgatg aaaaaaacaa caaaattatt ggcaacagga atgttgtctg
     1441 tagcaatggt ggcaccaaat gtagctttag cggctgaaaa tactactgca aatacagaat
     1501 ctaattcaga tattaatata aatttacaaa gaaaaagtgt agtgttagga agtaaatcta
     1561 atgcaagtgt aaaatttaaa gaaaaattaa atgctgattc aataacatta aattttatgt
     1621 gttatgatat gccacttgaa gctactttaa attacaatga aaagacagat tcatatgaag
     1681 gtgtaataaa ctataacaaa gacccagaat acttaaatgt atgggaactt caaagcataa
     1741 aaataaatgg taaagatgaa cagaaagttt taaacaaaga agacttagag tctatgggat
     1801 taaatcttaa ggattatgat gttacacaag agtttataat aagtgatgca aattcaacaa
     1861 aagcagtaaa tgaatatatg agaaaaactt ctgcaccagt aaaaaaactt gctggagcta
     1921 ctagatttga aactgctgtt gagataagta aacaaggttg gaaagatggg tctagtaagg
     1981 ttgtaatagt taatggagaa ttagcagcag atggaattac agctactcca cttgcatcta
     2041 catatgacgc accaatatta cttgcaaata aagatgatat accagaaagt acaaaagcag
     2101 agttaaaacg tctaaatcca agtgatgtaa taattatagg tgatgatggt tcagtttcac
     2161 aaaaggcagt gtctcaaatt aaatctgctg taaatgtaaa tgtgactcgt attggtggag
     2221 ttgatagaca tgaaacatct ttacttatag caaaagaaat agataagtat catgatgtta
     2281 ataaaatata catagcaaat ggatatgctg gtgaatatga tgctcttaat atttcatcaa
     2341 aagctggtga agaccaacaa cctataatat tagctaataa agattctgta ccacaaggta
     2401 catataattg gttatcttca caaggtttag aagaagctta ttacataggt ggtagtcaaa
     2461 gtttatcatc aaaaattata gaccaaatat ctaaaatagc aaaaaatggt acttcaaaaa
     2521 atagagtttc tggagcagat agacatgaaa caaatgcaaa tgtaattaag actttctatc
     2581 cagataaaga gttgagtgca atgttagttg caaaatctga cataatagtt gattcaataa
     2641 cagcaggacc tttagcagct aaattaaaag ctccaatact tataactcca aaaacttatg
     2701 tttctgcata ccataataca aatttatcag aaaaaacagc agaaacagta tatcaaattg
     2761 gtgatggaat gaaagatagt gttataaatt ctatagcatc tagtttatca aaacacaatg
     2821 caccaacaga accagataat tcaggttcag cagcaggaaa aactgtagtg atagacccag
     2881 gtcatggggg ttctgattca ggggcaacaa gtggattaaa tggtggagca caagaaaaga
     2941 aatatactct taatacagca ttagcaacta ctgaatattt acgttcaaaa ggtataaatg
     3001 ttgttatgac tagagataca gataaaacaa tggctttagg agaaagaaca gcattatcaa
     3061 atactataaa gccagattta tttacaagta tacattacaa tgcgtctaat ggagctggta
     3121 atggtgtgga aatttattac aaagtaaaag ataaaaatgg tggaacaact aagactgcag
     3181 catcaaatat cttaaaaaga atactagaaa aatttaacat gaaaaataga ggaatcaaga
     3241 caagaacact tgataatgga aaagattacc tatatgtgtt aagaaataac aattatccag
     3301 caatacttgt tgaatgtgca tttattgaca ataagagcga tatggataag ttaaatactg
     3361 cagaaaaagt aaaaacaatg ggaactcaaa ttggaatagg aatagaagat acagtaaaat
     3421 aaaatagaaa atattaaagc aaaacatatc atctcctgtt ataatgtaaa atataacaag
     3481 agatgatata tttttgtaaa gaatcaaatt gtttacaatg atgtttcttg tattgataat
     3541 ctgctcatta ttgagtataa tatagaaata agtcaaaaat aagatagaaa taagttgaaa
     3601 ttaagaatta aaaaaatttt tattccaata tggaggtaac tatgtctgga tatactaatg
     3661 atgagtgtga aatacctaaa attaaaagct atccaggggc agataaagaa attgcaagtg
     3721 agattgacta tagcatagta aaaggaacag ttttattcga cttgtaccaa agaattatgg
     3781 atttagtttt atctataata ggacttgtga taggtttacc tttaatagca atatttggaa
     3841 ttcttattaa aatagaggac aaaggaccaa taacttataa gcaagaaaga ctaggaaaat
     3901 gcgggagaag attctatata tataaattga gatctatgag aacagacgca gaaaaatttg
     3961 gcgcacaatg ggctgaaaaa gatgatccta gaataactaa ggttggaaag tttattagga
     4021 aaactagaat tgatgagatt ccacagctgt ttaatatatt aaagggggac atgggcttaa
     4081 taggtcctag accagagaga ccgaacttta ctgttcaatt taatgaggaa atacctggat
     4141 ttatcaacag gctcgctata aaacctgggc ttacaggttg ggcacaagta aatggtggat
     4201 acgaaatcac tcctgaagaa aaacttaaag aagatattta ctatataaaa aataggagta
     4261 tattacttga ctttaagata ctctttaaaa ctgttaaagt agtattgaca ggagacggag
     4321 ctagataatt ttaaaatatt agattactaa tcaatgaaaa agctctttaa aaagagcttt
     4381 tttattgtca aaaaatacaa aaaagaaaag gaatgagaac ttatgattaa aaaaatttct
     4441 actatattat cgttagtttt gttaatctct atttctagta cgataggagt atttgcagat
     4501 gcaaatccca aaagagaatt gatagaaggg agtataccag agatttcgac agaattaaat
     4561 aaaagagcat ttaaggattc taaagaagta attcttgtaa atgaagagtc aattgtagat
     4621 agtataagtg caacaccttt agcatatgca aaaaatgctc caatagttgt aactaagagt
     4681 aaaaatcttg gtagagtaac aagaaattat ctaaaagaac taggtccaga gaaggttacg
     4741 atagtaggtg gtttaaaggc agtatctaaa gatgctgaac gtaatataga aaaaatggga
     4801 atgaaagtag aaagaataag agggaaagac agatatgata catctttaaa gatagctaga
     4861 gaaatgtata gaacagtagg atttgatgaa gcatttttac ttagctcaac aacaggatta
     4921 gagaacgcca tatctgtata ttcttatgcc gctaaaagtg gaatgccaat aatatgggct
     4981 aaagatgaag ggtttgagga acaaattgat ttcttaaaag gcaaaaatct taaaaaaata
     5041 tatgcattag gtgattcaaa agagtttatt gcagagattg attctaactt aaaaaatata
     5101 gaaggaataa agcaaataaa taagtcaagt acaaatgttg atttaataaa gaagttttat
     5161 gatgaaaaag atataaagaa aatctatact gctagattag actttggtag tagatctgat
     5221 gtaaacgaat atatttcttt gggagtagta tcagcaaaag aaaatatgcc aatactgatt
     5281 tgtagtgata acttaagtcg tgcacaagat aaattcttga aagatagcaa tataaatgat
     5341 gtagttgaag ttgggtatac agtaggtgat tatagtctat ttaagagcat atttaatcta
     5401 acattcttat cttgtatagt attaatacta ttattactat tgattacatt tagggcactt
     5461 agatatgagt cgaaatagtt tttgatttat aaggaagctt ttcataggtt aaatttactt
     5521 aattagaata atgtttataa gcagttttaa aagttctact tttagagttt aaattagata
     5581 aggagaaaga agatgtcaaa aacagctaaa gcagcattgt ggattatggc agccactatg
     5641 ttttcaaaag tattaggttt ccttagagaa cttgtacttg caaatttcta tgggacaggt
     5701 atgtatgcag acgtatttgt attaacatta aatatacctg gtttaatcat agcagtcata
     5761 ggctctgcag ttgctacaac ttatatacct atgtactttg agacaaagaa aagactcgga
     5821 gatgaaggtg ccttaaaatt tactaataat gttttaaata tatgctatat aatggctata
     5881 gtaatagcta ttattggtct tttatttaca gagcaatttg ttacagtatt tgcagcagga
     5941 tttagaaacg accctgctaa gttccaagca gcaatattat ttactaaaat aatgatttca
     6001 ggagttttat tcctgagtgg aagtaagata tttagttcgt ttttacaggt gaatgacagt
     6061 tttgtaattc ctgggcttat aggaatccca tataatatta taataatagc agcaatagca
     6121 ctaagtgcag gtaaaaatgt atggatactg ccagcaggag cattattggc tatggcgagt
     6181 cagctattgt ttcaactgcc atttgcgttt aagaagtcct acaagtataa gccatatata
     6241 aatttaaagg atgagtctat aaaagagtta gtcaacctag tattgcctat gttggtagga
     6301 gtagctgttg gacagttaaa tatatttgtt gaccgattat tggcaaccac tttgggtgat
     6361 ggaaagttgt ctgctcttaa ctatgcaaat aggctaaatg agtttgttat ggcattattt
     6421 gttacatcta taataacagt tatatatcct aaactagcaa aaatgtctgg taaagataat
     6481 aaagaaggat ttataagcac tattgtaaaa tcttcaaatt gtattatatt ggtggtgctt
     6541 cctatatcta taggagctat tatattagca gagcctcttg ttagaatatt attccaaagg
     6601 ggtaaatttg atgcgttatc aacagacctt acatctatag cgcttagatt atattcacta
     6661 ggtttattgg cttgtggagt aagagatgtc ttatataggg cattttactc tctttcagat
     6721 acaaaaacac caatgataaa tggaagtata gctttaataa taaatatagt tcttaattta
     6781 atattgataa gaccattggg tcatgcaggt attgctatat caactagtac atcaaacata
     6841 attacagtta tattattatt tatatctctt aaaaagaaaa atggatattt tggaggggat
     6901 aaaattataa agactggtct aaaaagtttg gtagcatctg gtgtgatggc agtagctact
     6961 ttattgatat ataataatct atatgcattt atgggttcag gaacaattaa agaaattata
     7021 tcagttggag ctggagtatt aggtggagct tctgtatata ctgtattgat agttttattt
     7081 aaggtagaag agatggattt agcttttgaa tttttaagaa aaggaaaaca aaaactactt
     7141 agaagataga taattacctt gaaattttaa attagagtca gaaaggatga aaatatggat
     7201 tataagaata attatgagat gtggttaaat tctccttatt ttgatgaaca aacgaaaaat
     7261 gagctattaa gtataaaaga tgatgaaaaa gaaatacaag atagatttta taaaaattta
     7321 gagtttggaa caggtggttt aagaggtata ataggagcgg gaactaatag aatcaatatt
     7381 tatactgtta gacgtgcgac actgggcgtt ttaaattata tcatgaaaac tcaaggagaa
     7441 gaaggtaagc aaaagggaat agttatagca catgatagta gatacatgtc tagggagttt
     7501 tgtatagaag tagcaaagac tttaagtgct tatggtgtaa aggcttatat ttttgaagaa
     7561 ttaaagccta caccagaact ttcttttgct gttagatatt taaagtgtgc tatgggaata
     7621 gtaataacag caagtcataa tcctaaagaa tacaatggat ataaagtata tgactcagat
     7681 ggtggtcaaa tctgtataga tatggcaaat gatataatag cagaagttaa taagattgat
     7741 gattacagta ctattaaaag tatagatttt gaagaagctt tatctaaaaa tttaataact
     7801 atattagata atgaagtaga tgatgagttt ataaaagctg ttaagaaaca agttttaaga
     7861 caaaatataa tagatgaata cgggaaaaaa ttaaaaataa tatatacacc tattcatggt
     7921 acaggaaata agccagtaag aaaagtctta aatgaatgtg gttttgaaaa tgtaatggta
     7981 gttaaggagc aagaattgcc agattctaat ttttcaacag taaagtatcc taatcctgaa
     8041 gaaaagtcag tgtttaatat agctattgaa atggcaaaga ataatggcac tgatttgata
     8101 ataggaacag accctgattg tgatagagta ggtatcgttg taaaagattc aagtggtgaa
     8161 tatgtagtct taaatggaaa tcaagtcggt tcacttttag ttagatatat attagagagt
     8221 ttagttgaag aaaataaact tcctaaaaac aatcctacaa taataaaaac tatagttaca
     8281 tcagaactag gtgcaaaaat agcaaaggct tataatgtag attgtttaaa tactttaaca
     8341 ggatttaaat ttataggaga aaaaataaaa gcgtttgaag aaagcaatga tagaagtttt
     8401 ataatgggat atgaggaaag ctatggttac ttaattggaa ctcatgctag agataaggat
     8461 ggtgttgtat cttcacttat gatatgtgaa atggcagcat actattcttc aaaaggtatg
     8521 aacttgtatg aagctttgat agatacatat aataaatttg gatactacaa agaggactta
     8581 aagtcagtaa ctttaaaagg catagatgga ataaaaaaaa taaaagagat gatgctttac
     8641 tttagaagtg ttaaaataga taatgtggct gatgtaaaag tagataaaat tttagactat
     8701 aaagatggtg ttgatgattt acctaagtca gatgtactta aatttttact tgaagatggc
     8761 tcttggatag ctataagacc ttcaggtaca gaacctaaaa ttaaatttta ctttggagca
     8821 aattcagaca atcaagaaga tgtagaattt aagttgaaca atttaatatc ttatatatta
     8881 aatgtagtgg attctatata aaaagctaag gggagataaa caatgaaagt atacaatgtc
     8941 ataatggctg gaggaggagg aactcgtttc tggccactta gtagacaaga agtacctaaa
     9001 cagcttataa atttaagtgg agaagatgct ttaataaacg aaactataaa cagaatagat
     9061 tctctagcaa aaaaagatga tttatttata gtaaccaatg agaagcaatt ggaagcttta
     9121 aaggatatag taaaagataa atgtttggat agtaatatat tgccagagcc atgtgccaga
     9181 aatacagcag cagctatagg ctttgcagca tttaacataa tgaaaaaata tggtgatggt
     9241 gttatgtgtg tatatccagc tgaccattat ataaaagatg aaaaagaatt taaatctatt
     9301 ttggaaaaag ctatctatat agcagaaaat aatgataaac tagtaactat tgggataact
     9361 cctacatttc catcaacagg atatggatac ataaatttta atagagaaaa tactatagaa
     9421 gatgttgcat atgaggtagt ggagtttgta gaaaaaccaa actatgaaat tgctaaagaa
     9481 tatgtaaact ctaaaaagta tgtatggaat agtggaatgt tcgtatggaa ggtatctaaa
     9541 atactagaag attttaagag atacttgcca aaagtatatg aaaaattaga agatataagt
     9601 aaatacttag gaacaaaaga agaaatggaa aaaataaaag aaatataccc aactatacaa
     9661 tcaatctcta tagattatgg tattatggaa agaagtaatg atgttatagt agttcctggt
     9721 gattttggat ggaatgatgt tggttcttgg gattctctag gtgcaatata tccaactgat
     9781 gatgaaggta atatcaaaag aggtgaaaat attactatag atactaaaaa ttcaattata
     9841 tattcagatg acaaattaat atcaacaata ggtattagtg atttgatagt agtatctaca
     9901 aatgatgcag ttatggtttg tagaaaagat aaagctcaag atgtcaaaaa aatagtagag
     9961 cagttaaaag aagaagatag acaagaatat atgtaggagg tgttcatttg attcctaaaa
    10021 aaatacatta tgtatggttt ggtggtccaa aaggaaatat agaaaatata tgtataaatt
    10081 cttggaaaga aaagcttcca gaatatgaga tagtagagtg gaatgaaaaa aactttgata
    10141 tagagaaaga aataaaagga aataagtttt tggaagaatg ttataaaaga aaactttggg
    10201 cattcatatc tgattataca agaataaaag tactctatga acaaggtgga gtttatatgg
    10261 atacagatat gcaaatatta aaggatataa ctcctctttt agaaaataat aggctagtct
    10321 gtgggtatga agatgataga gagtatataa atggtgctat aataggtgta gaaaaaggac
    10381 atcctttttt aaaagactta ttggagtatt atgaaaaaga agtacttact tcttcattgt
    10441 ttacaatacc aaagataatg actcatctta tggaaaagaa ttataagaag attgatccaa
    10501 ataattatga agaaggaata cgtgtttacg acaaagaata tttttatcct tttggattta
    10561 aagaagactt tacaccagaa tgtataacag aaaacacttt tgggatacat tggtggggaa
    10621 aaagttgggc taaaaagaga aattatttct tagaaagcaa acacttaaca ggtgtaaata
    10681 agatatggaa gtgttgtaaa atatttgcaa gtaatacttt acgaagctaa aagggagaaa
    10741 gtaaaatgaa gactttaaat gatgatagaa atattatgat tagaaaatat ctttatatat
    10801 ttgttttgtt tatcatatta cttagaaagt atatgatatc atttattgac ccaaatatgg
    10861 atatagggat gattaaatca gcgttatttt attcttcaat aggaatacta atgctacttt
    10921 ttttatttga taagagaaaa agtataacag aaatggtact agttggagtt tgtgtcttac
    10981 tttatttatt aaatagggaa ggagctatat tattaatcgt tttattagct gtatcagcta
    11041 agcaaataga tgataaattt atagttaaaa attatttaat aatatcggca tgttttttaa
    11101 tggtagctat attattattt aatttatttc cttcattaat atttaatcag gaagtccact
    11161 atagatatat agaaaaaata gatatgcttg ttacaagaat ggattttgga cttggtaatc
    11221 caaatagtgt attttatcat atggttacta tatatgcagc atatatattc ttaagatata
    11281 aagattataa taaatgggat agaatacttt tatttggttc tgcatttttt gtttatcaaa
    11341 ccacatatag tagaactgga tttttcacta tattagcagg attaatattt gtagaaataa
    11401 taagatggat agatataaaa aaaataaaag gactaccaat gctcctaaag acattaccgg
    11461 taatacttac tttatttagt gtaattattg gtacagtatt tgataaaagc actttattaa
    11521 atagattatt agcaagtaga cctaagttct ggaatgtata cttggctgaa aaggggaact
    11581 ttctaaaacc ttttggaaat tcatatagtc ctgctataaa agcaactaat ccattagata
    11641 gttcttatgt atatataatt agtgtactag gagtagttgc ttgtatatta tttatgtatt
    11701 tgatgtataa aggaatagaa agctttatag aaaaagataa aaaagcatat ttagtagctt
    11761 tatttatatt tttactatac tcttttgcag aaaatttatt attagaagct tcatttagtt
    11821 ttgcagtagt attactaata aaagaagtga tattaaatga taaaagggaa atagatttgt
    11881 ggaagatgaa aagtaggagg tagtaatgtt aatatcatta ataatgccaa cattaaatag
    11941 atatgatgat atatacttac ttatggacag cttagaaaat caaacttaca aaaactttga
    12001 acttatagta gtagaccaaa atgataatag caaagttaaa gaaatagttg ataaatacat
    12061 tgataagtta gatataaagt atataaaaag ctctaaaaaa ggattgagtt ataacagaaa
    12121 tgtaggcata gacaatgctg tagggcaaat tataggtttc cctgatgatg attgtgtcta
    12181 cgaaaatgat acattagaaa aagttataaa tttctttaat aaaaataaag attataaaat
    12241 atacagttgc aaaactatgg attcaaataa agttgatgca tttaagaaaa tgtatgatgg
    12301 aacttgtgat atcacaagtt ccaacgtttt ggatactata acatccataa ctttttttat
    12361 tgattttgaa ggtaaagact atacaagatt tgatgaaaaa ttgggtgttg gtggagagtt
    12421 tggtgctggt gaagagatag attatgtttt aaacttattg agtttaggtt ttaaaggaaa
    12481 atactttgga aatgatataa tttaccatcc tgcaaaaaaa cattctaaat ctaaagaaaa
    12541 gtatcaaaaa gattataact atggaagagg ctttggagcg ctttgcaaaa aggaaatagt
    12601 ctatagaaaa aattataagt ttgcaaaagt tatggtatca aaacttgtaa gaaatatagg
    12661 aggtcttata ttgagttcca atagagatta tcatagtgcc actataaaag gaagaattaa
    12721 tggatttaga cagtacaagt tataatgagg atggtgttta tggacaaggt taaattttta
    12781 ataaatatgc ttttggcttt ttttatatat ccatttaata agcataagtt taatggtaga
    12841 gatatctggc ttataggtgg acattcaggg gatatataca atgataattc aaagtttttt
    12901 tatgagtata tgctaaaaga acataatgat gtagaaactt attgggtagt aaataaagac
    12961 agtaaagtat ttgataaaat tccaggcaaa aaattaataa gaggaagtgt agaaaactat
    13021 ctgtattatt acaattcaaa agctatagta ttttcacatg caccatcagc agatatagca
    13081 ccatacaatt ttgctgtacc tgttcttaat tattttcata aaaaaacgat aaaagtgttt
    13141 ttaaatcatg ggactataag ttttaaaaaa agaaaaccta tgaacaaaaa gttcaaaaat
    13201 attatagata acctatataa aagctataat atagttacag caagttctga atttgaaaga
    13261 aatgttatgg taaatgattg gggaatgtta gatgactcag tttatataat tggaaatgca
    13321 agatatgaca atttaccaac aaatgaagtt gcacaaactc gagatatatt atatactcct
    13381 acatggagag attggataaa atttagttca ggaaaattta cggatacaga ttattttaaa
    13441 aatataatga attttttaaa tgatgacaaa ttaaataaaa tattagatga gaaagatata
    13501 aatgtaaaaa tttatatgca tcatcttatg catgagttta tagatgatat aaaagaaaat
    13561 ataacaggaa aacgaattgt gtttttagat aaaggggtaa ctctagcaaa tgaaatcaga
    13621 aaatcagctg caaatataac tgattattca agtgtagcca tagacttttt gtatatgaat
    13681 agacctatct tgttttacca attcgatttg gatgaatata tggaaaaagt tgattcatat
    13741 atagatttaa aaagtgaaat gtttgggtct ttggcttata ataatgatga agccgtgaat
    13801 aaacttattg atattattga aaataatttt gaggttatgg ataaccaaaa aaatgaaaga
    13861 aataagtttt tcagatataa tgataataag aactgcaaga ggatatatga ttgtgtatta
    13921 agtaaaatta aataaatatt ttataaatga tgaggaaggt aatatgaaga agaatttagt
    13981 atctataatt actcccatgt ataattctga aaaatttatt gaagcaacca taaaatcagt
    14041 attaaaccaa acttatcaag aatgggaaat gttaattatt gatgattgct caacagataa
    14101 tagtcctaat atagtcaaat cttatatgca acaggatagt agaataaaat gtataaagac
    14161 tgagactaat aagggtgtct ctaatgctag aaatttagca ctaagtaagg caacaggaca
    14221 atttatagct tttttagata gtgatgacca atggaatagt agtaagttag aaaaacaagt
    14281 aaattttatg ttagaaaatg actatgtaat ttcatttact tcatatgaac tgatggatga
    14341 aaatgataaa aaattaaaca aagtaataaa agttccacct aatgtagatt atagaagatt
    14401 attaaaagga aatatcttag gatgtcttac tgttgtgatt gataagtcta aattggattt
    14461 tgaaataaga atgagtggtg taagacatga agattatgtt ttatggttat cgatattgaa
    14521 aaaagggcat attgctcatg gaataaatga agttctagca ttatatagaa aatctagcaa
    14581 ttccctaagt ggtaataaaa taaaagctgc tatgtggact tggaatatat atagaaatat
    14641 agaaaaaata cctttataca aagctatata ctactttatt aattatggaa taaacggaat
    14701 caaaaaaagt tagacagaga ggaagattta attaatgtat aaatataaat ttactgtatt
    14761 tactccgacg tataacagag ctcatttact tgaaaatttg tacaatgatt taaaagctca
    14821 aacttatgat ttcaatgatt ttgaatggtt gattgttgat gatggaagta gcgacagtac
    14881 taaagagtta gttgaaaaat ttatatcaga aaataaatta aatataagat atatatacaa
    14941 agaaaatgga ggaaaacata ctgcaataaa tctaggtgta aaaaatgcag atggagagct
    15001 atttttcatt gtagatagtg atgatggttt aattaaagat tctcttgaaa ttgctaatga
    15061 tgagtgggat tctttagaga ataaagaagg atttagtgga gttgttggac tttgtgtata
    15121 tccaagtgga gatttgatag ggacagaaat gcctgaagat aagaaaatat gtcactttgc
    15181 agacctatat tttaagtatg gcgttaaggg agataaaagc atagtatttg taactgatga
    15241 gcttataaaa tttccttttc cagaaagaaa agaagtgaga tttttaccag aaagtgtagt
    15301 atggaatgaa atgtctaaat actataaagt tatatgtgta aataaaccta tgataataag
    15361 agattatttg gatgatggtt tgactaagaa tatattaagt aaaaatgcat taagaggtag
    15421 agcattagag tttttatatt taataaatca aaatacatat ccattaagta gatatccata
    15481 tatgtggata aaaaattaca taaatttagc cagatactca ttgttgtctg atagtcatta
    15541 ttttggtgaa ttaagaaaag tatctgataa attgttgtat ttagcattat tcccattagg
    15601 atattacaaa tatattggac aaagaaaatt agtatctaag taaacttgtt ggtatagtac
    15661 tgctagttgc tatataagga gagtaaaaat atgaatgagc ctttagtatc gataattact
    15721 cctgtttata attcagaaga gtttttatca gagacgataa agtcaatcca aaatcaaact
    15781 tataaaaatt ggcagctttt attagtggat gattgttcta aggacaattc aagtgaaatt
    15841 ataaaaagtt ttcgaaaaga agatgctaga ataaaatata taaagcttga aaaaaattct
    15901 ggagctgcag tatctagaaa tgttggtatt aagaatgcgg aaggtcgatt tattgcattt
    15961 gtagatagtg atgatttatg ggatagtaga aaattagaga ttcagataga atatatgtta
    16021 aaagaaaatg taggtttttc ttttacatct tatagatata tgagacaaga tgggtcaaaa
    16081 acgaataagg ttgcaagagc tcctaagaaa attgactatg aaggattact tagaaatact
    16141 ataataggat gttctacagt ggtcattgat aaggagattg taggagagtt cagcatgcct
    16201 ttggtaagaa gaggacaaga tactgcaacc tggttacagt tacttaaaaa ggaaaaatat
    16261 gcatatggga ttcaagaaga tttagtgaat tacagattag ttggaaattc tatatcaagt
    16321 aacaagataa aagcattaaa acgaacttgg aatacttata gaaatgttga aaatttaagt
    16381 ttaccaaaaa gtctatatgt attttgtttc tatgttttta atgccattaa aaaaagagta
    16441 taagttttat atacttggag gtaaaaaaat gaaaatagct atagctggga cgggatatgt
    16501 aggtttggtt acaggtgttt gtctagcaga ggtaggcaat gaaaatgtag tctgtgttga
    16561 tgtagatgaa caaaaagtta aatcaatgaa acttggaata gcacctatat atgaagaagg
    16621 cctagaagaa cttatggtta aaaattacaa cagaggaaga atagattaca ctacagacta
    16681 taaaaaagct tatgaagatg tagatgtaat attaatagct gtaggtacac ctgagagaag
    16741 tgatggttca gccaacctag attatataaa ggtagttgca aagcaaatag ctgaaactgt
    16801 gacaaaagat actctagtag taataaaatc tacagttcca attggtacaa atgaagagat
    16861 agaagattat ataaatagaa acctaaaaaa tgatgtaaaa gtagaacttg catctaatcc
    16921 agagttttta tcacaaggaa cagcagtaaa agatactcta catgcttcaa gaatcgttat
    16981 aggtgtagaa agtgaatggg ctagagaaat attagaggaa atctataagc cttttaatca
    17041 acctataata gttacaaata gaaatagtgc tgagatgata aaatacgcat caaataactt
    17101 cttagctctt aaaatatcat ttatgaatga tattgcaaat ctttgtgaaa tagcaggagc
    17161 taacatagaa gatgtagctt taggaatgag ttatgatgat agaataggaa gtaagttttt
    17221 aaaggcggga ataggatatg gtggttcttg ctttccaaaa gacacaaaag ctcttcactg
    17281 gttatctgaa cataatggtt atgaattaaa aacagtaaaa gctgcaatag aagttaatga
    17341 aagtcaaaaa cttaaattag ttagaaaggc atctaagtta gtagagagct ttcaagatat
    17401 gaaggttgct gttttaggtt tgacttttaa gccagacact gatgatataa gagaagcacc
    17461 atctatacca aatataaaat atttgctcga aagaggggca agagttactg tatacgaccc
    17521 aattggtgta aataatacta agaaaatatt tggtgactct atactttatg ctgattctgt
    17581 agatgatgcg atagaagatg cagagatatg ttttataatg acagaatgga aagatgtatt
    17641 aaattatgat atacataagt ataaggaaaa gatgaaaaat cctttagtcc ttgatggaag
    17701 aaattgttat aaaattaaag atatggaaga gttaggaatt gagtattatt cgataggaag
    17761 gtaaatatta tgaagactgt ttgttattta gctgatgggt caaatcctca tactttaaaa
    17821 tggtgtagtt tttttaaaaa taaaggatat gacattcatg taatctcttt aaatggaggt
    17881 cacatggaag gaataaaaat ttataatttt ggttctaatg tagaagaact aaaaaatgaa
    17941 aatatttcta aaaaaacggg atacttaggt tcaataaagc agataaagaa gctagtaaat
    18001 gaaataaagc cagatatatt gcatgcacag tatgcaagta gttatggatt tataggaagt
    18061 ctacttgggt atcatccata tattatttct gtttggggta ctgatattta tgatttccct
    18121 aataatggtt ttatacaaaa acaaattata aagcataact ttagaaaagc agactatatc
    18181 ttttcaaata gtagagatat ggctaaagag gctaataaat atacagctaa acatgtagat
    18241 gtaacctttt ttggagtaga tatggatagg tttaagccta tggaagtaga aaaagaagac
    18301 gcttttgtaa taggaattat aaagagttta gaaaaaaaat atggaataga atatttaata
    18361 caagcattta agatgcttaa agatgaatat aaagataaga aaataattct taaaataggt
    18421 ggctctggaa gtcagatgga caacctaata aatttagcta aagaattggg tatagaaaat
    18481 gatgttcagt ttttaggaag aatatctcca gaaaatgtaa gcaagacttt taattctttt
    18541 gatgtaactg tatttccttc tttaagagag ggatttggag tggcagctat agaatcagaa
    18601 gcatgtgaag tacctgttat agttacaaat gtaggaggac atccagaatc tgtatgggaa
    18661 aatgaaactg gcttaattgt agaaccaaaa caaccagaag aaataaaaaa tgctataata
    18721 aaactaatgg aaaatgatga acttagactt aatatgggta agaaagggcg tcaatttgtt
    18781 agagaaaatt atgaggttaa tttaaacttt aatgatatag aaaaaattta tgattctata
    18841 tttgataaat ataaaaaata aaatgaaaaa atacagcaaa agatagatgt tgttggctat
    18901 gcttaggtgc gtagcttttg ctgtttaaag gagggcttct agttatgcga gaaagtatag
    18961 atttagagaa agaaagcttt tttaataggc tttttaaaaa atataaattt agacatttaa
    19021 cactattaat tctagatatt tgtagcgtac tagtagcgtt tcgaatgtct ttaagcttga
    19081 caggtaattt aaatgcattt accactaatg atataataat ttcagtgtgt atatatatag
    19141 tacttcatat agtatcattt agattgttta agtgctacaa cacattatgg agatatgcag
    19201 gagaagaaga aattatatct atttttgtgg caactttagc ttatttaatt ccgatttata
    19261 taataaataa attattaggg tttgattatc ctataatgtt ttatgtatta aatacaatat
    19321 ttattataat gtttacaagt ggcgcaagaa tagcctatag agctataaga atagtcatga
    19381 acaagacata ttctagagga aaggtttcaa atatccttat aattggtgca ggagatgcag
    19441 gagaaatggt tatacaggaa ctaaaaagaa atccagaact taagaaagta gcagtggcta
    19501 taattgatga tgataaaaat aaaattggaa gaataatcca taatgtgaaa attgtaggaa
    19561 caacttcaga tataaaagat gtggtagaaa agcacaatgt agatgagata atcttttcaa
    19621 tagcaaacat agagaaacgt agaaaaaaag agattattga tgtatgtaaa aacactaact
    19681 gtaaaataaa gacaatacca ggaatttacg aaattataga tggaaaagtt gatataaaac
    19741 agattagaga agtagagata gaagacttgt tgggtagaga gcctataaaa acaaatttaa
    19801 gagagataag taattacatt gagggaaaag taatcctaat aactggagga ggaggctcaa
    19861 ttggttcaga gctttgtaga cagattgcag gatttaatcc taaagagctt attatagttg
    19921 ataattatga aaataatgct tactcaatac aacaagaatt acttagaaaa tataaaaata
    19981 aattagattt aaagacagta atagcatcaa taagagaaga aaaaagaatg gatgaaatat
    20041 ttaataaata taaaccagaa gtggtatttc atgcagcagc acataaacat gttcctctta
    20101 tggaatcgag ccctggcgaa gctataaaga ataatatatt tggaacttta aacatagctg
    20161 gcttgtcttc aaaatataga gctaagaaat ttgtccttat atctacagat aaggctgtaa
    20221 accctactaa cataatggga gctactaaaa gagctgctga aatgattata cagactatga
    20281 atgctgaaag ccagactgaa tttgttgctg ttagatttgg aaatgtgctt ggtagtaatg
    20341 gtagtgtaat tccacttttt aagaagcaaa ttgaagatgg cggaccagtg acagttactc
    20401 atccagatat tattagatat tttatgacaa taccagaagc agtaggctta gtcatacaag
    20461 ctggggctat ggctaaaggt ggagaaatat ttgtacttga tatgggagaa cctgtaagaa
    20521 tattggattt agcaaaaaac ttaattaaat tcagtggatt tgagccagat gttgatataa
    20581 aaattgaatt ttctggtctt agaccaggag aaaagttata tgaagaacta cttatgtcag
    20641 aagaaggtct gttggataca gagcataaaa agatttttat tggtagacca atagatgttg
    20701 atagagaaaa aataacaaaa tacttaaaac ttttaagaga aattactaac aatgaagagg
    20761 ttgaaaaaat agatggtatt atgagggaat tagtgccaac ttatattaaa ccagaagatg
    20821 ctaatatcaa agaaattgca acaactagag aaaagtagaa tatatttcta atttgtaacc
    20881 agggggagca aaaagaaaca aatatatact aaaaagaaac aaaagattac aaaaagatta
    20941 caaaaagatt acaaaaaagg ttgcaattta ttttgatgta agatagaatg ttaattagga
    21001 attggaaacg aaggaacaaa atgttaaatt ttcgaaagga ttaggtattt gagattatga
    21061 tgaatattaa aaataaaaaa catatattga aaaaatttat agctatggtg ttaatagcag
    21121 gagttgtcac agtagaagca ggagcaataa cggctagtgc agcagagcca actaattcac
    21181 ctatgagtgc aacagtagac cagtgtgatt ttttaaatgt aagaagtgga gctagtgcaa
    21241 atgatgcagt agtaggaaag ataaacacag gagacaaagt tgaagtttta gaattacatt
    21301 caaatggatg gattaaaata aaaagtgttg acaatgttac aggatgggta aatggagatt
    21361 atttaactat tcaaggtgga aatgtagatg caaaggtaca aaatgtttta aacttagcat
    21421 ttaagcaaca aggtaagcca tatagatggg gagcaactgg accaaatgct tttgattgtt
    21481 ctgggttcac ttcttatgtc tataaaaatg gagcaggagt taatttacca agagtatcaa
    21541 gatcacaagc aacagtagga aagaaagtat caagagcaga attaaaacca ggagatttag
    21601 ttttctttgg ttcaggtggt tcaataaatc acgttggatt gtatgtagga gattctaaat
    21661 tcatacattc accacaaaca ggagatgtag taaaagttac tagcatggct ccaggaacta
    21721 attatgcaag aagacttata actgctacac gtgttttaca ataataatag atattgattt
    21781 acataggatt gaatattaac attaaatata taattacatt taatgtttta catagagatt
    21841 taagagttta gtaatattaa aatagtgatg aacgttataa aaacagcaaa gaagataaat
    21901 ttctttgctg ttttttttat aataaattat ttcatattat aatcaaatat caaatataaa
    21961 ttttaactat attattcaat atttgacaga taatatgaat tttagatata cttaataaga
    22021 agtatattgt agaaaaaata aatttaaaaa attaaggggg atgaaatgaa aaaaataagt
    22081 atattagtat tatcattgat aatgacactt actatgtgta gtgtaagttc atttgctgat
    22141 tcatcaaatg ataaagaaat gagagctgct tggatatcta cagtttataa tttagactgg
    22201 cctaagacta agaataatga agccaagcaa aaaaaggaat acacagattt attggacaaa
    22261 ttaaaaagtg taggaataaa tacagcagtg gttcaagtaa gaccaaaatc agatgcttta
    22321 tataaatcaa atataaaccc atggtctgaa tatcttaccg gtacacaagg taaagaccct
    22381 ggatatgacc cattaccatt tttaatagaa gaagcacata aaagaggaat ggaatttcat
    22441 gcatggttta atccatatag aataactatg gcagatgaga gcatagataa attgccagca
    22501 aaccatccag caaagaaaaa tccaagctgg gtagttaaac atggaaataa gtattactac
    22561 gacccaggtt taccagaagt tagaaagtac atagtggata gtatagcaga agtagttcaa
    22621 aattacgata tagatggagt tcattttgat gattacttct atccaggagt aagtttcaat
    22681 gatactgcaa cataccaaaa atatggaaaa ggacaaaata aggatgattg gagaagagaa
    22741 aatgtaaata ctctacttag agatgtaaaa gcgtctataa agagtataaa gcctaatgtt
    22801 gtatttggtg taagcccagc aggtatatgg agaaataaga gtagtgaccc aacaggttca
    22861 gatacatcag gtaatgaaag ttatgtaggt acatatgcag atacaagagc atggataaaa
    22921 caaggattga ttgactatgt agttccacaa ctttactggc caattggtct taaagcagca
    22981 gattattcta aattagtggc atggtgggct aatgaagtaa aaggaacaaa tgtagactta
    23041 tacataggac aaggtatata taagcaaggt caatcgagtt atggtggaca aaatatagca
    23101 aaagaaatag tacaacaagt aacattaaat agaaagtata gtgaaataaa aggtagtatg
    23161 tatttctcag ctaaagatat agcaaatagt acttctatac aaaaggattt aaagagttta
    23221 tattctagta gtgaagaacc agttactcca ccatctaatg ttaaagtgga gaaattaaga
    23281 ggcgacgaaa gatatgacac agcagtagca ataagtaaaa aaggttgggc tacaaattca
    23341 gatacagtag tattagtaaa tgggtactct atagttgatg gtataacatc aacaccactt
    23401 gctacatcaa atgatgctcc tatactattg gtaaataagg ataatatacc tacatccact
    23461 aagaatgagt taaaaagact taatccaagt aaagttattt taattggagg aaataactct
    23521 attggagata aagttgagag tgagataaaa gatacattgt caaatgtatc aataaataga
    23581 gttggtggtt cagatagata tagtacatct ttaatgatag caaaagaatt agtaaaaact
    23641 aatccagtag aaaaactata tataacaagt ggtacaggtg aagcagattc tctttctata
    23701 gcttcaaaag caggagaaga aaagcaacca atagtattag tatcaaaaga taatgtaagt
    23761 gatgaagttt acaattggat atcagattta aaagtaaaag atgcttattt tataggtggt
    23821 aatctaagta tatctgattc agtaataaat aagctggata aggtcattac aaatgatgta
    23881 tctaaaaata gaatagctgg agaaaataga gaagaaacaa atggaaaagt aatacaaaaa
    23941 ttctatccaa atgctgaata ttcatcaatg tttgtaagta aaagtaatca attggtagat
    24001 gcattaacat caggtccttt agcggctaaa ttaaaatcac cagtagttat gcttggaaat
    24061 agtgtaacat ctgctcagaa aactgcttta gagcctaaga aaactactct agtatacgaa
    24121 gctggagatg gtataaatca aaacacatta aacactttct taaacttagt taagtaataa
    24181 aaaagttaat ttaaaataca gagtatttta caaatgtaga ttaaaatgaa aattatcatg
    24241 ataaattaga aaataaaaaa gaactatatg cattttgtaa tcaagtgtac acagcaactt
    24301 gaaaataatt atgcgatata gttctttttt agtaattaat cttatacttt ttaataaact
    24361 ttatgttgaa ttttttattg tttaaactct atgtcattaa atataaaatc gtgtaatatg
    24421 tctaaagtat ctgggtcaaa tctaagaacc catccagctt ttccatatat accacctgta
    24481 ctatgaattt catcatcaat aggaaattca aattgcttaa tatttaagtc acccattttt
    24541 aaaacttgag ctcctaaaga aagtattgca ttaggcttca tgttagtttt aacatatgga
    24601 agaactgcat ctaataaacc tggatattta gtaacaggta aagtttccgt tttcttgatt
    24661 atagcttgta taatctgtct ctgtctgcca tctctagcaa aggctgtatc gttgtgtctg
    24721 atacgtgcaa aagatagtgc ctgatatcca tttagagtct gctttccaga gtttctaatg
    24781 tattgtatgc tacctttatc atcactttta ctccatttat aagtttcagg aataaattta
    24841 tttagttctc gtatttctcc tttttcaaca gtaacctcaa cgccaccaat agcatcaatt
    24901 atatacataa atgattcgaa attaacacaa gcataatttt gaatatcaat attaaaattc
    24961 tcttcaattg tttgtattaa taaatcagct tgtccataag cataagcatg agtaagtttt
    25021 tgtttaccat gaccagggat gtctacatag ctatcacgag ctaatgatgt aagtttgata
    25081 tcattgtgtt tgttatcaat agtaagtatc atcatagcat ctgaccttga agaatcttca
    25141 tttggtctag catctgttcc cataagtagt atgttaatta tcccatcttc atttttatgg
    25201 tcattgttat ccaataaatc actacttatg ctcgagtcat gaatagcaga taatttataa
    25261 taaaaatatc catagacact tatagggaat attactacca agaaagccag tagtataaca
    25321 aatttcttta attttgacaa aagtacccct tctttcttct ttttcctgta tattttttaa
    25381 tagcatacac ttaattatat taaagtattg agatatattc aatacttgtt tcagttacaa
    25441 aaaaaagaca atgatataat ttataagaaa atttatcgac ctatatatat agttaaaagt
    25501 atatataata tattttttaa aagtaattta tattttaaaa taaaaacaca ccccataaat
    25561 acaaagtaat ttgcatttaa gaggtatgta tttatcatca aattattggt ttgttttgga
    25621 atttctaatc ttcaaccata atatctttaa atatgaaatc atgcattgca tctagttcat
    25681 attcctcaaa aggtattaca tagcctgcat tacctatttt tctaccattt tcagtagaaa
    25741 gaggaaactc catagatttc aaatttaaat ttcctatact taaaagttct tttcctaaag
    25801 atattatttc attaggattc atattagttt ttacatacgg aagtattgtg ttaactagat
    25861 taggatattt agtgactggt aaatccttaa caccatttat taaactctgt ataacacttc
    25921 tttgtcttct atctctttca tctgtactat cattttttct tatacgagaa aatgcaagtg
    25981 tctgatatcc atttaatttt tgctcaccag aatttcttat atatttaaga gaacctttat
    26041 tgtcattttt attccattta taagtttcag gaataaattt atttaattct cttatttcac
    26101 tcttatcaac agtaacagta actccaccta aagcatcaac tatatccata aaagagaaaa
    26161 agtcaactac ggcgtagttt tgtatatcaa gttggaagtt ttcttctata gtttctatta
    26221 ataagttagc ttgtccatat acgtaggcat gtgttaattt ttgttctcca tgtcctggta
    26281 tattaacata agtatctcta tttaatgaag ttagcttaag acttttattt ttattatcaa
    26341 tagtaagtat catcatggca tcagaacgag aaacttcttc tcctggtctt gcatctgtac
    26401 ctaacaataa tatgtttgtg atattttctt cgtttttata gtcattacta ctaagcgcct
    26461 ctgtatttat actatcatct tgtatagttt ttaatttagt aaaaacatat ccatatatac
    26521 taacaggaaa tgctataact aaaagggcta gaaatataac gaactttttg agtcctgaca
    26581 ataatatccc ctactttcta aattttttaa ttacacatag ttaattatat taaaaatttg
    26641 ttacataagc aataaaaaac acaataaatt agcataagtt tgtcataata taattatttt
    26701 tatagcattt tatagaagaa agtgtgtagt tattattgat tttattggaa tataattgta
    26761 tgaagactta aatttttata aactaatgtg tatattgaaa aaaatatttt cctgaatgta
    26821 gttatagcat cttatgaaag gtgcaaattg taatttaaaa tttttagtgt ataataagaa
    26881 ttgaaaattc aaaccgataa aaattaataa aaaataatta taaattaata atttggggga
    26941 ggaaatgtat gataaaatta atagcaacag atttagatgg aactttgtta gatgaaaaga
    27001 gcgaaataaa tccagagttt tataaagtat ttaaaaaatt aagagagaga gggataatgt
    27061 tttctgctgc tagtggcagg cagtatcaaa atctgataaa aaaatttgaa gatataaaag
    27121 atgatatgat gtttatatca gaaaatggaa cactagtagt atataaagga aaagaaatat
    27181 tatcaaatcc tttaaataaa gaattagtaa atgaaatcat agagacaaca agaagtataa
    27241 aagggaaaaa aattgtaatg agtgggaaaa aatacgctta tatagaaagc aaagatgaag
    27301 cgtttataca agaggttagt acttattatg caaagtttaa aattgtagaa gatttgacga
    27361 aagtagaggg agacatattg aagatagctg tgtttgactt caaaggtgca gaacataata
    27421 ataatatcta ctttgaaaag ttttctgata gagctcaagt atgtatttct ggagtggagt
    27481 ggcttgattt aactgcaaaa ggtgcaaata aagggagtgc cataaaaaaa gtacaaaaaa
    27541 tgttagatat aaaatatgaa gaaactatgg tatttggtga ccagttaaat gatgtggaaa
    27601 tgatgaaaag tgcctatcat agttatgcca tggaaaatgc aaatgaacat ttgaaacaaa
    27661 ttgctagatt tagagcaaaa agaaatactg aaaatggcgt tgtagataag ataaaagagg
    27721 ttataaaaat tggatagtca tatgtataga tgaaaaagat tattttgaag aaatcaaaaa
    27781 aatatcaatg taattttgat aaataagttt atttatgcga aaattacatt gatatttaat
    27841 aaacatcaat aatagatatt tattttttta tgatattcag tattttgttt tctatttgag
    27901 ttgcattttc agcagaaatt aaataaacat acctacctgc cttctcaatt atagtattat
    27961 ttgctatttc agaattgatt ttttctccat gtccttctcc aaaaggtgct tgtatcatat
    28021 cttttttata attttctaga gttttataga ttttatctac ctcgtcagtt tttataacga
    28081 taatatcttc tagagataat ttttcagaag aattaattac aaaaccttga attatgtctt
    28141 cctctacatc attaaaatag ttaaaatcct ttgcatcaaa gatttttgat tcctttataa
    28201 gtaaatcaga agattttaat gcttttttta tttttgatgt agaaacgttt ttgtaatcac
    28261 cacttgaaga acaactaacc attcctaatg ataagattat cgaaaaaaac aatattaaaa
    28321 tttttttcat gataaacctc caagtttttt aaactctgtc ttaaattagt ttactacata
    28381 attatataaa aataaatgta tttaatgtta cagttttgat taataatgta atattttgat
    28441 aataatacct attgagaggt gattagaaat gagaatacca aaacatgtag gaattatacc
    28501 ggatggaaat agaaggtggg caagtcaaaa tggtatgaca aaagataaag gatatgaaag
    28561 tggaatagac cctggactag agtcttatag attatgtaga gatttaggct gtgaagaggt
    28621 gactttttat ggatttacaa ctgataatac aagacgtcca tcagtgcaga caaaagcttt
    28681 tacaaaagca tgtattgatg ctgcaaatat attaatagat gaaggtgctg ctttattagt
    28741 tgtaggaaat acaaaatcgc caatgtttcc agaagaatta ttaccatata ctaatagaat
    28801 taaagccaaa gaaggtcaaa taaaagcaaa tcttctggta aattatggtt ggtattggga
    28861 cttaaataat atatcaggag tagaaaatgt aaataaaaat aatatacagg attacataca
    28921 gtcatttgat gtatccagac tagacttgat aatcagatgg ggtggaagaa ggagattaag
    28981 tggtttcctt cctgtacaat caatttatgc agatttttat gttatagata attattggcc
    29041 agattttaag agtgacgata taaaggacgc atttagttgg tatgatacac aagatgtcac
    29101 tttaggtgga taattaaaaa tattctgatt taaggttgta gagtgtttta aattattgaa
    29161 aaaaaaactt cttgatggta aaataacact aataatatgt aaaagtgtaa aaatttatac
    29221 caagaagggt gaagaaatgt caaaaggcaa taataacaat aattcaagaa acaaatctaa
    29281 aaagaccagt catctgaata gaaaaaagcg aaaattaaat aagaaaaagt tagcagtgtt
    29341 gatttgcttt acagttttat ttttatttat tgcatttaag gctactcaag gtgtagtagc
    29401 tttggtaaaa agtatggata aaagtaataa aactagtcaa caacaaaatg ttaactcaga
    29461 acaatttgac cttggtaatg aagaggaaaa taaaaagaaa aaatatactg tatttataga
    29521 cccaggtcat ggaggcaatg ataaaggaac tgaaagcaag accagtaata gatatgaaaa
    29581 agacctaaat ctacaaattg caaaaaaatt agcaaataaa ttatctaaac aaaaggatat
    29641 tcaagtagta gtatccagaa ctgatgatac atatatatca ttaaaggata gagctatctt
    29701 agcaaataat agttctgctg atgtgcttgt ttctattcat ttaaatgcag agaaaaatgg
    29761 taatacagca acaggtatag aaacttggta taggaataaa gctacagatg gttcaaaaga
    29821 acttgcacag acagtacaaa gtactatagt atcctatgtt aaagttagag ataggggaat
    29881 agttgaaaat aactttgaag tacttagaga atcaaatatg cctgctatat taatagagtg
    29941 tggtttttta acaacacctt cagaggaaca aaaaataata aatgaaaaat atcaagacca
    30001 acttgcggaa ggaattgttc aaggtgtact ttcataccta gattctaaag ggaataagta
    30061 aattaacttt actttaatgt gaggataaat ttaaaagttt aactgtgtaa attgtattaa
    30121 ctttatttcg taatgttgga aatattgttt gaatttagaa actatgaaat tagaaattat
    30181 tttatctata tctaatttca tagttttttt tgcaaaaaat ttatagttat aaaattttaa
    30241 aaaataaatt tagtataatg taatgtagtt atttatatgt gattttaact tgcattgatt
    30301 tgctatcaat tgtgctttat aattagtata tataaagttt aactgtaaga taatttaaaa
    30361 aataggggaa tttatatgaa taaaaatagc atgacaagaa tttacagttt aaataaaata
    30421 atttttatta taattggaat tttaggaata gttttactca caagacatat tgaggtagat
    30481 attaaagttt taattttaat tttattaacc ttgtttagta taaatgtatt tatttcatat
    30541 cttaaaatta agttgtatga ggataaaatt aatttaggat tgataaataa ttcagataag
    30601 tttataaata ttactaaaga tgagaacttc ctaaaacatg ttcaaaatta tattatcagt
    30661 aatgaaaaag aaaactgtgt aatggcttgt tttgatttat gtagactcaa acttataaat
    30721 gatatatatg gttatgagct aggggatgaa gtgttaaata atattttaag taacttaaaa
    30781 aattattttg gaaaagaagc tatttatgga aagttaaaaa gtgatgtttt tgtattaata
    30841 ataaagcttg aaaataggga acagaagatt ccttatttag taaatcttat taagaataaa
    30901 attgtgatac taagtcagat tgacagtttt aaaatggata taaatattga ggcttctatt
    30961 ggaatttata aatttaacaa taatgaaatt gatataaaaa aagctataga taatgctgat
    31021 atggcaaggc ttaaatcaaa aggactaaag cacatagagt atgtagaatt tgataatgct
    31081 atggaagaag aaatacaatc aattatgaaa atagagagag atttattctt ggctattaaa
    31141 aataaagagt ttgtaattca ctatcaacct aaagttgatt caagtacagg taacattata
    31201 ggttcagagg cattgataag atggttgcac ccatcattag gcatggttgg accaaataag
    31261 tttataccta tagctgaaaa aaatggtctg ataaacaata ttggtagatg gctaattcaa
    31321 gaagttttta ttaccattaa caagtggatt tcagaaggta taaatgtctt accagtctca
    31381 ataaatcttt ctagagtaga actatataaa aatgatttag ttgatttttt taaactgatg
    31441 tttaatacat ataatattcc aaaagaactt atagaattag aaattacaga aacgacagca
    31501 ctaagagatg taaaatttat aagtgaaagg ctttatgaga ttaaatcttt aggtatgaat
    31561 atatcattag atgattttgg agtaggtaat tcaaatttta tcaaccttaa ggggatacca
    31621 ctagatatta taaaaattga taggtcactt atattggata tagttacaaa tacaaaaaca
    31681 aagtttatgg tgaaagcaat tgttaacctt tcacatgatt taaacgtaac tgttatatgt
    31741 gaaggggtag aggatatgca tcaggtcaaa gtcttaagtg aactgggatg taatttcata
    31801 caaggttatg tattttttaa acctttggat gagatgaatt ataaaaaact tcttactgac
    31861 ggaagttata taaatctgaa agatactctt ttagataaat gcatgacagt tgaggaggag
    31921 taaggatgat ttcagaagat gtagattatt caataagaat cataagagct atatttaata
    31981 atggagaaga taaaccaata gatgctaaaa tgatattaaa aagtgaagat ataccaatac
    32041 taacactata cagactgctt agaaagcttt gtgcaaacaa tattcttact tttaacaaag
    32101 aagatggcaa gacatacatg ttaaatgtgt cattggatac aataagtcta agaactattg
    32161 tagaagtaat tgatggaaaa atatatataa ataaatgtac gagatatgta tctaattgca
    32221 gtaattgctt aaaaggttgt aaagtaaatc gtgaattgct agaaatagaa aaagaaattt
    32281 ataaactttt atcgagaaaa tctataagac aaatactaga ataaaaaatt ttcagctatg
    32341 ataataattg gaggttttcg gttatggatg atatatctca agataatttt ctactgtcta
    32401 aagagtatga gaatagctta gatgtagata ctaaaaaagc aagtggaata tattatactc
    32461 ctaaaataat tgtagattat attgtgaaaa aaactttaaa aaatcacgat ataattaaaa
    32521 atccatatcc acgaatactt gatatttcct gtgggtgtgg aaattttctt ttagaagtat
    32581 atgatatttt atatgactta tttgaggaaa atatatatga attgaaaaag aagtatgatg
    32641 aaaattattg gactgttgat aacatacacc gtcatatatt aaactattgt atatatggtg
    32701 ctgatattga tgaaaaagct ataagtatat taaaagatag cttaacaaat aaaaaggtag
    32761 taaatgattt agatgaatct gatataaaga ttaatctatt ttgttgtgat agtcttaaaa
    32821 agaaatggcg atataagttt gattacatag tgggtaatcc accctatatt ggtcataaaa
    32881 aacttgaaaa gaaatataaa aaatttctcc tagaaaaata tagtgaagtt tataaggata
    32941 aagctgactt atatttttgt ttttataaaa agattataga tattttaaag caaggaggga
    33001 ttggcagtgt tataactcca agatattttt tagaaagtct atcaggtaaa gatttaagag
    33061 aatatattaa atcaaatgtc aatgttcaag aaatagtgga ttttttaggt gcaaatatat
    33121 ttaaaaatat aggggtatct agttgtattc taacttttga taagaaaaaa acaaaagaga
    33181 catatataga tgtatttaaa atcaaaaatg aggatatatg tataaataaa tttgaaacat
    33241 tggaagaact tctaaagagt agcaaatttg aacattttaa tataaatcag agattgctat
    33301 ctgacgaatg gatacttgta aataaagatg atgaaacttt ttataataag atacaagaaa
    33361 aatgtaaata tagcttggaa gatatagcaa taagttttca aggaataatt acagggtgtg
    33421 ataaagcgtt tattttaagt aaagatgatg taaagttgaa ccttgtagat gataaatttt
    33481 taaaatgttg gataaaaagt aagaatataa ataaatatat agtagataaa agtgaatata
    33541 ggctaatata ctcaaatgat atagataatg agaatacaaa taaaaggata ctagatgaaa
    33601 ttatagggct atataaaaca aaattagaaa acagaagaga atgtaaaagt ggaataagga
    33661 aatggtatga acttcaatgg ggtagagaaa agcttttctt tgaaagaaaa aagataatgt
    33721 atccttataa atcaaatgaa aatagatttg ctatagatta tgataataat ttttcaagtg
    33781 cagacgtata ttcttttttt ataaaagaag agtatttaga taaattttca tatgaatatc
    33841 tagttggaat tttaaattcc agtgtttatg ataaatactt taaaataact gctaaaaaaa
    33901 tgagtaaaaa tatatatgat tactatccta ataaggttat gaagataagg atttttaggg
    33961 ataataatta tgaagagata gagaatttat caaagcaaat aatatcaatt ttattaaata
    34021 agtctataga taaaggaaaa gtagaaaaat tgcagataaa aatggataac ttgataatgg
    34081 attctttagg tatataagca gttgtaagta ttaaaaaatt ataatctttt aattgtttat
    34141 ttaaatttag aaataaaaag ttagccatat aaaaaatatt aaaaatatat acttttcaat
    34201 atttttttga taaaataaga atgaatttgt gcaattttat ttttctccaa taactaaaaa
    34261 tagttttttg aattaatatt tgcttaagaa taaaaatcag aaacgttttt gatatagtag
    34321 gtgataatat gaaaggatta gttttagaag gtggaggaac aaaaggagcc taccaaatag
    34381 gtgcatataa agctttaaga gagcttggta tagagtttca aggagtaact ggcacatcaa
    34441 ttggtgcttt aaatggagca tatataattc aaaatgatat tgaagtaatg gaagatattt
    34501 ggttaaatta tgactatact cattttatga atattgatag agaaacctat gagaggttta
    34561 aaaatgtaga tttcactact aaaaatctca atgcagtgtt tgagcttata aataaagcta
    34621 gaaaaaatga aggtatagat ataagcccat taagacaatt aatggagaca acattaaatg
    34681 aagacataat aaggaaatca aaaaaagact ttggacttgt tacggtctgg tgggataaaa
    34741 aaattaatcc atatccattg tatatcgaag atatacctaa aggaagattg attgattatt
    34801 taattgctag ttccagtttg cctatttttc aaacgaacat gatggatgat aagttgtatc
    34861 ttgatggaat gttttgtgat aacatgccaa taggactctt ggaagacaaa ggttatgaag
    34921 atgttgttgt aattaggttg attgatgatt ttattgggaa aatgaatcta aatcgacatc
    34981 aaaatataaa tataaaaact ataataccat cagaatatct aggaggttct cttaataaag
    35041 atagagataa tgtagaaaaa aacatccgac taggttactt agatactatg aaagcatatg
    35101 aaagatgcac tggaattaag tattattttg atgtagagta taaatataat gaagaatatt
    35161 gttttgataa atttagaagt atgagcaatg aaacaataca atatatctgt aatttattga
    35221 atataaaaag agatgcttca cttagaactg ttatggaaag tgtaatacca aagcttggtg
    35281 aggtgcttgg attgccaaag gatttttcat ataaagattt gttttactgt atatatgaaa
    35341 agaaacttga agaaaataat ataaacagga taaaattata tgattttaac aaggttatag
    35401 atgttgtaaa tacaaatatt gattctaata gaaatttagc ttctaatttt gaagttagac
    35461 ctaaaattag tattaaaaag aacaaaaaca caaaattatt gacaaattgt attataaaag
    35521 acataaaaaa tcaaagttaa ataaaaaaca aaaaaaaatt tgtaattata ctcgaaaaaa
    35581 gtgtatatta gtagtataat atttttgtag cactagtggg aacaaaaaat gaccatagga
    35641 caaaaaagta ccacttagta ccattaaagt aaaaaacagg aaaacaattt taaaaaatat
    35701 aaaatgtaaa gtttatagga ggatttaaaa aaatggaaaa agtagttagt atcaaaaatg
    35761 caagtggatt acatgctaga ccagcaggaa tgtttgttaa gaaggcagct gaatttaaat
    35821 caacagtaga ggttgtagca aaagacaaaa ctgtaaatgc aaaatcaata atgggaataa
    35881 tgagtttagg tttagctcaa ggagaagaat taaagttagt tgtaaatgga gaagatgaag
    35941 aagtagcttt agctgcaatg gttgaattag ttgaaagtgg atttggagaa tagatataat
    36001 aattttttaa aaatttgata tttagaatct aatattactt aaagtaaagt aacagagaag
    36061 tattaaacat atacagacca acatttgtag atatttaatt tctttgttac tttcatgttt
    36121 atttaatcag aagattaaga ctattgttaa ttgggtataa aaatataaat attttagaaa
    36181 atgaaataag atatttttaa tcataaattc agagtaaaaa tacagtaaca aatagtttat
    36241 aaaattttat aaaaaattat aagtaaataa aactataaaa atgtaaatta tttatataaa
    36301 tttataaagt ttatgtgcta gatgatattt tttaggaggt agagttatgg cttacaaagg
    36361 aataggtgct tctcctggtg ttgctttagg gaaagcgtta gtagttgaac atagtgaatt
    36421 agtaattgaa aaaaaatcta tagataatgt tgaagctgaa attgctaaat tagaagatgc
    36481 agttgcagtt tctaaagaag aattagtaaa agttaaggaa aaggcttctg aagaattagg
    36541 agcagaggaa gcagaaatat ttgaagcaca tttattagtt ttagaagacc cagagttaat
    36601 tggttctgca atagataaaa ttaaaactga aagtgtaaat gcagagtatg ctttaaatga
    36661 aataaaagag atgtttgtta gcatgtttga gtctatggac aatgagtaca tgaaagaaag
    36721 agcggcagat ataaaagatg ttacaaatag aatacttaga catatattag gaattaaagt
    36781 tgttgattta tctgctttaa gcgaagaagt tgtattaata gcacatgatt taactccatc
    36841 agacacagca actatgaata aaaaaatggt tttaggattt ttaactgata taggtggaag
    36901 aacttctcat actgctatca tgtctagaac tttagaaata gctgcaatcg ttggattaaa
    36961 tgatataact tcaaaagtta aggatggaga ttttgtggtt ttcaatggag acacaggtga
    37021 agtaatcgtg aatcctgatg aagagactat aaataaatat actgaattaa aagctaagta
    37081 tgaagatgag agaaaagcat tacagctatt aaaaggaaaa ccatctgtaa ctttagacgg
    37141 aaaacatgtg gaattagctg gtaatatagg aacacctaac gatatagaag gtctaataaa
    37201 gaatgatgct gaaggtgttg gtctttatag aacagaattt ttatacatgg atagagattc
    37261 tttcccaaca gaagaaatac aatatgaagc atacaaagct gtattagaag gaatggatgg
    37321 aaagcctata gttataagaa cattggatat aggtggagat aaagaattaa gttatttaag
    37381 tatggaacct gaaatgaatc cattcttagg ttacagagca ataagacttt gcctagatag
    37441 aaaagatata tttaagactc aattaagagc tttatataga gctagtgttc atggaagatt
    37501 aagaatcatg ttcccaatga tttcatcttt agaagagttg ttacaagcta aagaagttgt
    37561 aaaagaagtt ttagcagaac ttgattctga aggtgtggct tatgctaaag atgtagaaat
    37621 tggtatgatg atagaagttc catctgctgc tgtaatatct gatgtattgg ctaaacacgt
    37681 agatttcttc tctataggaa ctaatgattt aattcaatac acttgtgcag ttgatagaat
    37741 gaatcaaaag ataagctatc tttacaatca atttaatcca gctgttttaa gacttataaa
    37801 gactgttata gacaatgcac ataaagaagg caaatgggca ggtatgtgtg gagaatctgc
    37861 tggagaccaa aaaatgatac caatactttt aggtatggga ttagacgagt tctctatgtc
    37921 tccaatatca atacttcctg ctagaaagtt aataacttca gttaaagagt cagatatgaa
    37981 aaaattagct gatgatgtac ttaatatggg tactgctgaa gaaataaaaa gctatataga
    38041 aaagactttt aatatataat taatgttata tagttactaa aattcatttt tctaaataac
    38101 aaaattatat ttt
//
LOCUS       DAMJVG010000038        37895 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.038, whole genome shotgun sequence.
ACCESSION   DAMJVG010000038 DAMJVG010000000
VERSION     DAMJVG010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 37895)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37895)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37895
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.038"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(39..899)
                     /locus_tag="PC512_002000"
     CDS             complement(39..899)
                     /locus_tag="PC512_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-ADP-ribose hydrolase"
                     /protein_id="HDF2441742.1"
                     /translation="MAMKWRDYADDVNLFEDFDKTIKPLTDEQRRKNINTLIAYFSKE
                     VPSKIYNLSNDEIKPRDILRGLLNVYPPKEIAPEILNMLHNLLLIECEERELVDVNDI
                     EEVEEGIAIWRGNITNLRADAIVNAANNKLLGCLQPLHLCVDNEIHSCAGPRLREDCD
                     KIIKKQGHLEYTGDAKITRGYCLPAKFVVHTVGPIVSGGQPSKEQEKQLLHCYKSCLN
                     TIKEIDEIKNIVFCGISTGVFGYPKKEAANLAVSRVRLWLKENPEKNLKVVFNVFTEE
                     EEEKYRRIFK"
     gene            complement(1216..2544)
                     /locus_tag="PC512_002001"
     CDS             complement(1216..2544)
                     /locus_tag="PC512_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HDF2441743.1"
                     /translation="MEKFSVVIAGGGSTYTPEIILMLLDNLDRLPLRAIKLYDNDEER
                     QNKVAKACEILIKEKDPNIEYLATTCPKEAYTDVDFCLAHIRVGKLEMRELDEKIPLK
                     HGVVGQETCGPGGIAYGMRSIEGVLENIDYMEKYSPNCWMLNYSNPASIIAEAVRRLR
                     PNSRVINICDMPIGMEHNIARIAGLKSRKHMDIRYFGLNHFGWYTSIKDKKGNELLPK
                     LVEHIKEYGFINGEEGMKNDKKDSWFETNLFTKEIVKTDLTTIPSSYLKYYLFPDYVV
                     NHSDVNYTRANEVIDGREKEVFGSCALIEKQGHSKGSGLKIGIHAEFIVDLATALAFN
                     TQERMLLIVQNNGAIENIQDDAMVEIPCIVGKDGYEPLSIGKIPTFQKGLIEQQLAVE
                     KLVVDAWIEKSYNKLWQALMLSKTVPSATVAKELLDDLIEANKNYWPKLN"
     gene            complement(2692..3021)
                     /locus_tag="PC512_002002"
     CDS             complement(2692..3021)
                     /locus_tag="PC512_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDF2441744.1"
                     /translation="MVPEMEEKVFSIISEAGDAKSDVMMSLKEIKKGDYNKAKHLLNS
                     ASEKIQTASKHHLELLSNAMNSEDSGTDFLVVHSEDHYSNALFAHSLVSELVDIFEMM
                     DPRINKN"
     gene            complement(3045..4334)
                     /locus_tag="PC512_002003"
     CDS             complement(3045..4334)
                     /locus_tag="PC512_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2441745.1"
                     /translation="MEALQNNLRRFLLPIAQKIEKQRHLQAIKEGMISITPIIIVGSL
                     SMLFMALNNMLPEGSAKTLLSENMDTLLIPNKFTMSLLSIYSAFFIAQALAKKYNLNH
                     VEIGMTAVVAQLVVCGQVVDGVLDTSYLDAQGLFVSILVALLVVDITKFMNDKNLVIR
                     FPKEVPSVVNKSFRNLTPMIVCIMLFTAIAAITKNVSGQPLPAIIMNFLAPAISSVDN
                     VFAVTIILFITQLLWFFGLHGAAITSSIWMPIAATYMAENATLIAAGGDPKYVFTIGF
                     YYGFLQVTGSGITLGLVYLMSRSKCKSFNSMGKVVILPSLFGINEPVIFGTPIVMNPY
                     MFVPFVFGPVLVGALNFMALKVGLVGLPIAEPPGFLPPGVAAFLMTLDWKAIVLVFAS
                     IILMTLIYYPFFKIMEKEELNKNAELATTLDDDSFDF"
     gene            complement(4350..4676)
                     /locus_tag="PC512_002004"
     CDS             complement(4350..4676)
                     /locus_tag="PC512_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2441746.1"
                     /translation="MNILLVCANGASTGVLVEKMKSFCSEHEKLKTKTINIEATSFEN
                     LKSYIEANDTDVVLVAPQIRFKEDDVVEACKNYKIAVGLIDTKHYGRMDAPSVMKSAI
                     ELYKNR"
     gene            complement(4811..5440)
                     /locus_tag="PC512_002005"
     CDS             complement(4811..5440)
                     /locus_tag="PC512_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441747.1"
                     /translation="MQDKILRDKKANDPWARMTTRNGFSADEIISSFQKAIRRNMVEE
                     ACEFAYELYISSPELEDKLWRRILTISVEDIGMGDPSAVIIINNLNQVRKEYSYADGD
                     RPLFFIHAIRYLCACEKDRSSDLLKNIIIKGFAMGKVPEVMDVALDKHTYRGLEMGRD
                     SFHFLNEASIVIPEKEVDNDYKERYLKILEKYKQEEVIDTAFKFNHWQY"
     gene            complement(5656..8313)
                     /locus_tag="PC512_002006"
     CDS             complement(5656..8313)
                     /locus_tag="PC512_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2441748.1"
                     /translation="MIYKKDKVMKVLESSYRENEKGITANQLSEKTGIARNNISTYLN
                     QLFNEGMVTKIKGRPVYYIPANLNLNKNELLDTQSELLGIKKGTKVENKIKKDSFETL
                     IGKEHSLRPIIEKCKVAMLYPTNGLHTIIYGETGVGKSMIARYMYDYSIDSGIRKNKA
                     PFVTFNCADYANNAQLLMGHIFGVEQGAYTGAESSRKGLLEIANGGILFLDEIHRLPA
                     EGQEMLFTFIDKGTFKRLGDATKERESKVLIICATTENPTSTLLDTFNRRIPMKIEIP
                     SLRDRTMIERMELVKNFFKEESKSISISIKVHKEIIKSLLLYDCKNNVGQLQNDIKLA
                     VANGYLRYKRDNKEPVYIEKKYFDKSINEVSDDYREKSIKADEVITHGIEYFVFTSLG
                     EEEVINYNDINIINAVNTNLNKSVEMNIADASLFNNVKFKSMCESIRQIIKEDEEIDI
                     SESIFKSMAIYIKSVLDKSSSTNNIDLNQIRRNNRSEFKTALKIVGIIENEFDLFLSI
                     ETVAYITLFIVQAKQDEQNKIVNNINIIVAMHGETTASSMVKAVGDIIGKCSAISFDM
                     KLDKSYDEVIVDFKNLINNIDNKDVLLFTDMGSLNSFDEIIKKEKKCGVRVIPMVTTL
                     TVLEAVQKANMGLPLNDVYNSITNTRKHYFGTNEIQNKENLSKTIIIASHVSEGVDNK
                     TRKILEEKMSRYLDGIDIISVPYKTEKDLSLNITKLKESSNIVAVINEQRINIRGIDY
                     ISKKDIDKDENINKLKNIIKISIGYDDVVEGLKTSLKSSNYNRIFKDIKYVSDELFLV
                     FNIEKKYDKVIGLMMHLAFMVDGLIGNTREIEKLDKEKTLDYHKSLSKIKDIVSQLDK
                     KYNIEINEKECYQILLILEYAEIIEKDYQ"
     gene            complement(8672..9616)
                     /locus_tag="PC512_002007"
     CDS             complement(8672..9616)
                     /locus_tag="PC512_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009527644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2441749.1"
                     /translation="MNREKILEIKNLKQYFHLDKSTTVKAVDDISFDIYKGEIFGLVG
                     ESGSGKSTTGKTIIRLHESTGGEVIYKGNCISDKKTYKFIKKDVNKSMQIIFQDSTSS
                     LNPRMTIADIISEPLKIQGICKNKTDRMNKVYEMLKLVGLDRSYANKYPSDFSGGQRQ
                     RIGIARALSVDPEFIIADEPIASLDVSIQAQIVNLFKKLQQEKNLTCLFIAHDLSMVR
                     HISDRIGVMYNGKLVELADSNELYNNPIHPYTKSLLSAIPVPDPRYAKSRNRIEYNSN
                     GYDCSNEKSLSWIEVSDGHFVYSSKSEINKYQQNLKVV"
     gene            complement(9609..10634)
                     /locus_tag="PC512_002008"
     CDS             complement(9609..10634)
                     /locus_tag="PC512_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2441750.1"
                     /translation="MEHLLEVNNLSVSFKVEEGEVQAVRNVSFNLKKGETLAIVGESG
                     CGKSVLCKSLMRILPYNGYIKNGEVLLKSSDLVKKSEKEMEDIRGKNISMIFQDPMTS
                     LNPTISIGKQIAEAVIIHQGISKSEAKKRAIELIELVGIDNPEKRFKQFPHHFSGGMR
                     QRIVIAIALACNPDVLIADEPTTALDVTIQAQIIDLIKDLQHKIGLSIIFITHDLGVV
                     ATIADRIAVMYAGKIVEIGTVEDIFYDPRHPYTWGLLGSLPTLDSQDDYLYNIPGMPP
                     NLLNPPKGDAFAIRNKNALKIDYEKEPPMFKINDTHSAATWLLHPDAPEVDVPVRVNC
                     GRVISNE"
     gene            complement(10709..12277)
                     /locus_tag="PC512_002009"
     CDS             complement(10709..12277)
                     /locus_tag="PC512_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2441751.1"
                     /translation="MKLKKLKVLSLVMILSLMAGCSSGGDKDKKADTPKDGKVLVYGS
                     NDYTSINPALYEHGEINSLIFNGLTAHDENNKVVPCLAKDWKFDEATNTYTFNLRDDV
                     KWHDGEKFTANDVKFTIETIMNPDNASEIASNYEDITKIDVVNDNTIKITLKAPNTAM
                     LDYLTVGVLPKHALEGKDIATDEFNQKPIGTGPFKLEKWDKGQSITLVKNSDYFVKEP
                     GLDKVVFKIVPDDKAKAMQLKSGELDLAQITPKDMSNFEKDEKNFKVNIMKTADYRGI
                     LYNFNSKFFKDKKAKGLPNALSYAIDRKAIVDSVLLGHGVPAYSPLQMGPYNNPDIEK
                     FEYNPEKAKQEIEKLGWKLGSDGIYEKEGTKLAFEITAGESDQVRVDMAKICAQQLKE
                     IGVDAKAVVVTETDWANQDAHLIGWGSPFDPDDHTYKVFGTDKGANYSAYSNPTIDKI
                     LQKARETEDKDEKLKLYKQFQVEMTKDMPYTFIAYIDAIYVGKPNIKGLTPDTVLGHH
                     GVGVFWNIADWTIE"
     gene            complement(12390..13301)
                     /locus_tag="PC512_002010"
     CDS             complement(12390..13301)
                     /locus_tag="PC512_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2441752.1"
                     /translation="MKPQYSDFEIVGENYILVAEDEHIETKKTLSKKIKELPYISIII
                     LSIIVIGSVFSSFIMTHEPTYMDLASSNLAPNKTFLFGTDSMGRDIYSMIWYGGKISL
                     FIGLFSTVISTVIGIVYGSISGSASELVDDAMMRFTEIILSIPSILIIIFVQAILGNS
                     NPVSMSIVIGITSWMNISKIVRTEVRQIKNSEYILAAKSMGGGFFYVLKQHLLPNFVA
                     SIMFMVVTNIGAAIGTESTLSFLGIGLPIEIVSWGSMLSLSEEALLSNRWWIILIPGI
                     FLVTTLVCITNIGNYIRKNNNKKSSNL"
     gene            complement(13285..14271)
                     /locus_tag="PC512_002011"
     CDS             complement(13285..14271)
                     /locus_tag="PC512_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2441753.1"
                     /translation="MLKDILKKLLQFILVMFLLSFIVFYMARLAPGDPLISYYGDGVE
                     RMSTQEKENAMKKLGLDEPIYSQYIKWISNASKGEFGISFKYKQNVTSVINDVYINTI
                     ILGGSGYILTFVLALLLGIFCTLHEDKLIDRIICKLGTITNCIPSFWVALVLILIFSI
                     NLSILPSSGAYSMGEESSILSRISHLILPLTVLILSHLWYYTYMIRNKLLEEIREDYV
                     LLCKAKGLNNRTIVFKHCLRNIMPSYISIMAISIPHILGGTYVVEKVFSYPGLGTLCF
                     ESAKYHDYNMLLVLCLITGALVVFGNMLAQIINNKIDPRMKYDRGDTNEATI"
     gene            14631..15032
                     /locus_tag="PC512_002012"
     CDS             14631..15032
                     /locus_tag="PC512_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDF2441754.1"
                     /translation="MLLKELYSKTMYTVEENFKENGLTHQQIIVIKLIAHNQELTISQ
                     LCDEMSLAKGTVSGIISRLEQIGYIEKFKKSNDKRNTYVKFTTTGFEFATNFKIKMQE
                     SFDDIFKNCDENELSDLVKNLRNILAKVKER"
     gene            15035..15433
                     /locus_tag="PC512_002013"
     CDS             15035..15433
                     /locus_tag="PC512_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03987 family protein"
                     /protein_id="HDF2441755.1"
                     /translation="MNYKLILAIVFITSALIFYTIGVFGERKAKILKKKHVIIFWLGF
                     IFDTLGTFTMSNIANSHTFEVKSALSQNLHSITGLLAIVLMLFHASWATFVLYKDDEE
                     KKKFFHKFSIVVWTIWLVPYFIGMFIGMAG"
     gene            complement(15883..16107)
                     /locus_tag="PC512_002014"
     CDS             complement(15883..16107)
                     /locus_tag="PC512_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifU family protein"
                     /protein_id="HDF2441756.1"
                     /translation="MREKVEKVLEEKIKPVLQRDGGDVELIDVNENGVVLVRLQGACS
                     GCPGATMTIKAIIENVLVSEVPGVTQVLGV"
     gene            complement(16142..17509)
                     /locus_tag="PC512_002015"
     CDS             complement(16142..17509)
                     /locus_tag="PC512_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2441757.1"
                     /translation="MKEYIINNVEEIREELIDLSKKIWENPELAFEEKYASSIQKEYL
                     KSKGFKIEEVENLPTGFIASFGEGKPVIGILGEYDALPELSQCVSAERKPLVEGKAGH
                     GCGHNLLGVAGVGAVVSIKKLIEENKFNGTIKYFGCPAEEEGGGKTAMCINGCFDDVD
                     CAFTWHPFDINAPWRGGSLANLSVKFKFKGITAHAAQAPHNGRSALDAVEIMNVGANY
                     LREHVIDSIRMHYVITNGGGRPNVVPGFAESWYFIRGKKAKDAEHVLDRLIKVAQGAA
                     MMTETEMEYKVTDGIYDYIPNQCLTDLVYDNMVFVGCPKNTPEEEEFAKKLCDTLTRE
                     ERLGVATSLQNDKSIVESYIHKEIVDGDKDKGLAGSTDVGDVSYVIPVAQFAMAAWPV
                     GIASHTWQSCSSAGSNIGFSAMINSAKVLACSAYDVFMDTKIIDEAKIEFDKSLDGQK
                     FKPLV"
     gene            complement(17593..19128)
                     /locus_tag="PC512_002016"
     CDS             complement(17593..19128)
                     /locus_tag="PC512_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441758.1"
                     /translation="MLNNLSNININENNLIKNQYSISLLKECLNCKVIDEREVYNIQQ
                     EISLILMDLIKKYTNGQSTSVKTEVAEKLLISIWYAIDAYINKLGDIEKRVVELTAKN
                     VKKVYLGGIEILEEELVRLKDFYKLMMSRKLDTNSIAYNDTLMELSSFFKSYIVKFEA
                     QDVPVSIDYPLALDDMDVKGIYYVKNYIESIDIENRFCNLFKKKDREKLFYDYGVTYK
                     IDCDAILVNLFELIINNCIFSTILGNEVTNLEISKYEYEFLEKQFKNMYNNITEDKVI
                     DSEESNIIELIEVDDSFNTEVDSNLDYNDFEEINREIRINKKITLLLMEAIEVLIKRL
                     SIEDEDVIRYIKKYEKIFIESVLSSIKSNTFKSMVTVSKNKKEHLEDYIVDDESKLDD
                     ESFREIFNEILDSTSIIEKIRIIKENINAKKDFIDILESECLFGEEYLMLFASLSELE
                     LAILGSVVFYEDIRMREINILEFMLNEKTETTLWKIEYIKFMKRQSEDKIYSIEEHMN
                     KIN"
     gene            complement(19151..19585)
                     /locus_tag="PC512_002017"
     CDS             complement(19151..19585)
                     /locus_tag="PC512_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441759.1"
                     /translation="MISPIILSSINQNLKEIERNELLETNIESGDYGLALSESDVKDI
                     INSRDNTLKGYGRIELDIKVTKQLIENIYTSQYTNVDNYLEAINDMQEIFYYLKNETD
                     DKICDDEIIEILGEFYEKFSGNMDNVRGEADEFAKKFKFGEV"
     gene            complement(19845..20756)
                     /locus_tag="PC512_002018"
     CDS             complement(19845..20756)
                     /locus_tag="PC512_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CGNR zinc finger domain-containing protein"
                     /protein_id="HDF2441760.1"
                     /translation="MNKKIELIGNFASDWIRYSDYEYKITEEDELYIVPTEDAVFTMY
                     NPFDVADDIIVDIIRIGQEALQDISKETKEMKLKKEVLEFVKKYGLLGLIYSSVYNRD
                     IVGEERVLMIEKNYITKENILSTDEYVNMFIPFASDEDVYFKKYRRGIDVSKREESPK
                     FFGKRPLILDLVFSKFYTEQLDWIVSFAKDMCKHFNQICVYKNTSNLLTESVTIMSGG
                     FNPQKIGFSISQLDKPIIAWEFDSLKTAIETIYAFAITSEPSSLNKCKYCGKIYIPTN
                     SKSQYCSPSCRNCSNVKKSRSRAKKDK"
     gene            21052..21405
                     /locus_tag="PC512_002019"
     CDS             21052..21405
                     /locus_tag="PC512_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HDF2441761.1"
                     /translation="MDRKRELKQLYKEMKFDTGVFIIKNDITKKIYLGKSNDIKSKFN
                     SLKFQLGAGSCMIKELNNEWKKYGEKAFTFEVLELIKHDDNKTEKDYLEELDILEMVW
                     LEKLKEDNTYEIYSI"
     gene            complement(21624..22565)
                     /locus_tag="PC512_002020"
     CDS             complement(21624..22565)
                     /locus_tag="PC512_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp25"
                     /protein_id="HDF2441762.1"
                     /translation="MRISKKVLALGISALLLSVSFPTSINALDKIENIQGVDKYETAG
                     LISDKQDFTTAVLINADSTMVDGIAASGLAGVNNAAILLTNKDDIPEATLQRLNRVTK
                     IYVIGGENSISKDVEKMLLMRRMQVIRIDGVDRVDTSYKIAGEIEKIKNSDKMFLVNG
                     FKDEADAVSVASVAYRDGAPIILTKDIPSAEEDTDLDPWFGVSPVPVYAIGGESTLSD
                     YIVSRYRATRIGGVDRYQTNKNVIEKFYNGAKEFYITSGDDLVYALVASPLAKNAPVV
                     LVSNKSDKSILSGASKVTAIGISDKSIIEQCLDAVKK"
     gene            complement(22666..23901)
                     /locus_tag="PC512_002021"
     CDS             complement(22666..23901)
                     /locus_tag="PC512_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HDF2441763.1"
                     /translation="MKILHIITQKPNSTGSGIYLSGMIKGFEKIGHKQAVIAGIDVND
                     DVNCFPSEVSFYPVKYNCGELNFPVVGMSDSMPYESTRYKDLNIDMINRLKYQFKVNI
                     DKAMNDFKPELIICHHLYLLTAFVREMVKDIKVMSICHGTCLRQLNTIDLEKEYIIAN
                     IRKLDLIFALHENQKYDIIKTFGVSQSKVVVIGSGYNDDIFYNKNYKIKDDKIKIVFA
                     GKICKSKGLIPFIKAISKLKYSKDLIEVNFAGTGSDIESYNEIVKLASKSPFKMNFLG
                     KLEQRDLAELFNRSQIFVLPSFYEGLPVVVLEALSCGTDVITTDILGVKEWIGSEINN
                     SGKIEYVSLPFMEKEGIPKDEELYDFENNLYNAIDSKIQSLLNNSNKKTSVDMSKKTW
                     DGLAYRINEVILMDELCLI"
     gene            complement(23945..24799)
                     /locus_tag="PC512_002022"
     CDS             complement(23945..24799)
                     /locus_tag="PC512_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441764.1"
                     /translation="MALNIRNYSLLCNQGTAKFNEDVVGINPFGAWVLDGATGLNGKN
                     LVSTESDARWYVQWWNRYLYKNINKEESLKSIINTGIIEVKKEYELRLNGFKVEKLDL
                     PSSSIVVVKFHENKVEYFLLGDCALFIKNGDSKVIKDRSICKFDNTVFDEMSKLSNLE
                     EMAFDEIRTSVMDTIVSNRLKKNTKEGYWILDFDEEAVENSIYGYIEIKKDFQLMLTS
                     DGFTSACDRYNLIKEEELIRIAEKFGIGYIHNKVRDFEDNDYKAVKVPRFKVKDDSSC
                     LYLDIYND"
     gene            complement(24927..26102)
                     /locus_tag="PC512_002023"
     CDS             complement(24927..26102)
                     /locus_tag="PC512_002023"
                     /EC_number="2.1.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolecarboxamide
                     formyltransferase"
                     /protein_id="HDF2441765.1"
                     /translation="MARELELKYGCNPNQKPSKIYMKNGELPIEVLNGKPGYINFLDA
                     FNSWQLVKELKEATGLPAATSFKHVSPAGAAVGVPLSDTLKQIYFVDDLELSPLACAY
                     AMARGADRMSSYGDFIALSDVCDKETATIIAREVSDGIIAPGYTDEALEILKGKRKGN
                     YNIVKIDENYTPEPIETKDVYGITFEQGRNEILINEDLLKDIPTDNKIFTDSAKRDLI
                     IALITLKYTQSNSVCYAKDGQVIGVGAGQQSRIHCTRLAGNKADTWYLRQHPKVLNLK
                     FKKDIGRPDRDNTIDVYLSDDYMDVLADGIWQNFFEEKPEPLTGEGKRAWLKTLTGVA
                     LGSDAFFPFGDNIERAKRSGVSFIAQPGGSIRDDNVILTCNKYNIVMAFTKNRLFHH"
     gene            complement(26201..27085)
                     /locus_tag="PC512_002024"
     CDS             complement(26201..27085)
                     /locus_tag="PC512_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HDF2441766.1"
                     /translation="MKFVTFCSSNEEKIGVFNSETNSIYEINSLGLSKLYTDMNDFIE
                     NVSTGDLEKIKNNSFENAKCYKLEEVKLCSPIVRPKKDIICLGLNYKDHVNEIPDGVI
                     KNVVMPDYPIYFSKRADKIIGVDDKISLHGDLVEKLDYESELAVIIGKEGINISKEDA
                     YEYIFGYTIVNDISERALQDKHVQWFRGKSLDTHTSMGPCIVHKEEFEHPLKLDISSV
                     VNGEVRQDSNTEYFIFDIPTIINDLSRGMTLKPGDIISTGTPAGVAMGMNPQVYLKHG
                     DIVECKVEGIGVLKNIVD"
     gene            complement(27317..28003)
                     /locus_tag="PC512_002025"
     CDS             complement(27317..28003)
                     /locus_tag="PC512_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDF2441767.1"
                     /translation="MKYSYKKCIIDSILLMFIVQILRMILNYVLLSQFEFTLENFNII
                     NLISFTLVGLSLILFLKDNSLYNKVRNRKITEAFEENKNNILIEKCKLILFVVVLSLA
                     IIVTYCTKGYVLFNVTMMTLSVLIVPIFEELFFREYIWNYLSNFIKSKSKIICITSIL
                     SGIYNIGYIDVIRNYVILYNNSSYTFEVIISKIMIGTVFGIVLGLVKYRFRDVGFCIL
                     LRSLFAIFIR"
     gene            complement(28031..28342)
                     /locus_tag="PC512_002026"
     CDS             complement(28031..28342)
                     /locus_tag="PC512_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDF2441768.1"
                     /translation="MGIFKTKMDEDWKVNYIKEFNEMRDSYESKLQKKQFEVDSLKSE
                     LDRLRSYKNSLKPKEKQITDDDINNIKSLRRDGLSYKEISNQTSWSKATVSRVLNGLY
                     D"
     gene            complement(28531..29052)
                     /locus_tag="PC512_002027"
     CDS             complement(28531..29052)
                     /locus_tag="PC512_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF2441769.1"
                     /translation="MIGFLKKRRSIRKYKDVEVEKEKLDKILKAALLAPSSKGLRTWE
                     FIVVDDKEKLINLSQCRTKGGGFFLKNAPLAIVIIADKEKNDVWIEDASIAASYIQLQ
                     AHELGLGSCWIQVRNRMHDDNIEADKYIREELKVPSKYSVECIISIGYPDEEKKAYGD
                     SDLDYKKVHFNNF"
     gene            complement(29149..29643)
                     /locus_tag="PC512_002028"
     CDS             complement(29149..29643)
                     /locus_tag="PC512_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2441770.1"
                     /translation="MIRKANMNDLESIMQIIKSTVEEMKTYNNTQWDENYPLEKDFVS
                     DIKKQDLYIYEVDGEVAGFICLNYEEPEEYLGLNWSSNKKAMVIHRMAVNPNFRKTGI
                     ASKLVDFAEKLAVENNVSYLKSDTYSINSKMNLLLTKCGFIKIGEMSFLGKEKSFYCY
                     DKIL"
     gene            complement(29677..30150)
                     /locus_tag="PC512_002029"
     CDS             complement(29677..30150)
                     /locus_tag="PC512_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2441771.1"
                     /translation="MVVSVEVCLIKTLDSNILREVGTLSRAVNSINDIKYKELKLQKG
                     QFTFLTRICENPGINLVELSNMLKVDKATTTKAIQKLIKAGYVDKKQDKFDKRGYNLT
                     PTDKSLEVYELIIEEENRSIEICFDNFTDEEKQVVTKLLEKMSKNVENEWFKVKR"
     gene            complement(30476..31471)
                     /locus_tag="PC512_002030"
     CDS             complement(30476..31471)
                     /locus_tag="PC512_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocitrate/isopropylmalate dehydrogenase family
                     protein"
                     /protein_id="HDF2441772.1"
                     /translation="MYKVTLIPGDGIGPEVAKAMKKVVEATGVEIEWEEVNAGEAVIE
                     EYGTPLPEYIIDSIKKNKIAIKGPITTPVGKGFRSVNVTLRQALDLYVNLRPIKSFKG
                     IKSRYEDVDLVVVRENTEDLYAGIEHKIGDYAAESIKIITRSASERIVDFACNYVKDN
                     KRKKVTAIHKANIMKMSDGLFLDVFREVASKHGVEYDDLIVDAAAMNLVLNPENYDVM
                     VMPNLYGDILSDLGAGLVGGLGIIPSANIGKDCAIFEAVHGSAPQIAGQNKANPTALI
                     QSSVMMLRYLGEYENAQKIETALEKVFLEGSKLTVDLGGSASTTEFADEVCKYIV"
     gene            complement(31493..33418)
                     /locus_tag="PC512_002031"
     CDS             complement(31493..33418)
                     /locus_tag="PC512_002031"
                     /EC_number="4.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aconitate hydratase"
                     /protein_id="HDF2441773.1"
                     /translation="MGDNIVYKIIKKHIVDGEAVAGSSIGIKIDQTLTQDSTGTMTYL
                     QLEAMGIDKVKTKRSVAFVDHNMLQQGFENADDHKYIQTVADKYGVYFSKPGNGICHQ
                     VFLERFSTPGDTLLGSDSHTPTAGGVGMMAIGAGGLDVALAMAGGAYYIKAPKVCKVN
                     LVGKLNNMVSSKDIILEVLRKQTVKGGVGKVYEYGGEGVKSLSVPQRATITNMGAELG
                     ATTSIFPSDEKTLEFFKSQGREEAWIELKPDADAVYDEEITINLDELKPLAAKPHSPD
                     NVDEVENIGKIKIDQVAIGSCTNSSYEDLMKVAQILKGNKVHKDVSLVIAPGSRQVME
                     MIARNGALADIISAGARILENSCGPCIGMGQSPGTDSVSLRTFNRNFYGRSGTLSAQV
                     YLVSPEVAAVSAIKGVLTDPREFDIKFTNLDVNEFLIDDSMIIKPADVGSDVEVVRGP
                     NIKPFPLNTELSQSIGGKVILKTEDNITTDHIMPSNAKLLPFRSNIPYLANYCFNTVD
                     TEFPQRAKDNNGGFIVGGDNYGQGSSREHAALAPLYLGVKGVIVKSFARIHKANLINS
                     GIIPMEFCDEKDYENISLLDNLEIPNILDNLGSGILEVKNTTKGTSFKVKVELSAKEV
                     DVLKAGGKLNYTKNQAN"
     gene            complement(33443..34636)
                     /gene="nifV"
                     /locus_tag="PC512_002032"
     CDS             complement(33443..34636)
                     /gene="nifV"
                     /locus_tag="PC512_002032"
                     /EC_number="2.3.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homocitrate synthase"
                     /protein_id="HDF2441774.1"
                     /translation="MCVISKDRAKEIKIVDTTLRDGEQTAGVVFANREKIMIAEMLSD
                     LGVDQIEVGIPTMGGDEKNVIKHICSRNLKSDIMAWNRAVIKDVEESISCGVDAVAIS
                     ISVSDIHIENKLRTSRGWVLENMAKTVEFAKKNGLYVSVNGEDASRADIDFLTEFINV
                     GKQAGADRFRYCDTVGVMNPFSIKNAIETLYERTNFDIEMHTHNDFGMATANALAGIA
                     AGANYVGVTVNGLGERAGNAALEEVLMALKCVYKCDLNNIDTRKFRGICEYVAQASGR
                     ILPTWKPVVGDNMFIHESGIHADGALKDPHNYEPFDPSEVNLERKIVIGKHSGRAAVV
                     NKLSEYEMYISPENATKLLNAIRATSIRLKRSLMDKEILQLYCDILAHEKGTTEEEAV
                     RGSYI"
     gene            35098..36207
                     /locus_tag="PC512_002033"
     CDS             35098..36207
                     /locus_tag="PC512_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDF2441775.1"
                     /translation="MDFKSLGISENTINILKKSGITTPTPIQKESIKLIKEGKDVIAE
                     AQTGTGKTLAFLLPIFENISLDINDIQVLILSPTRELAIQITEEAMKLKESKDVSILA
                     AYGGKDIGSQIKKLKGNIHMIIATPGRLLDHLNRKTIDLSKLKTFVLDEADQMLLMGF
                     KNEVEAILKETSNKKQTLCFSATINSQVKKLAYRYTKNPVVVSIQKEEITLNNIKQEV
                     VETTDRKKLDALCKVLDEDNPFMAIIFCRTKRRVDNLEEALAIRGYNCQKLHSDIAQS
                     KRERIMKSFRNLDIQYLIATDVASRGLDISGVSHIYNYDLPETPEDYIHRIGRTGRAG
                     EEGYTCAFIDPKNERMLSEIETAIESKISRRIIEL"
     gene            complement(36584..37768)
                     /locus_tag="PC512_002034"
     CDS             complement(36584..37768)
                     /locus_tag="PC512_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441776.1"
                     /translation="MQKSVKKAKVTGSMLAIFGVASVLFSSHAGGGFATGNQETQYYV
                     QYGWTAPLMAILAMIILTATMREVIIMYNNNNCRNYKDLFCELWRPYPKLEIIWEIYY
                     YLMVLIAVSAVIAGAAAVFQSIGVNYFVAVFIIGVVLLVFTIFGAMLVSKAATAMTIA
                     ILVCTLTIFIVGIKAKVPEITEILSNRTSFTPGYIKPILNTFIYAGFQSVVIPTLAGC
                     SRPLLKNSKEATKAMIISFVMNAIALGLAVTMLMGWYREIIAAGQTTLPTLYVAGQSG
                     NHTIYIIYNVALFLCLMSTGVTTIFGLVNRFEDHKALSFLSSRMKRRVFTACAIMVVS
                     MLISLTGLSNIVKYGYGYCGYLGLFTIVIPFLTLGHYKNKKFAKENPEAKWPAELNEN
                     VN"
BASE COUNT        12186 a         6805 c         3959 g        14945 t
ORIGIN      
        1 ttatataata agtattttta ggattctgtt acataatatt atttaaatat tcttctatat
       61 ttctcttctt cttcttcagt aaacacatta aatacaactt ttaaattttt ttcaggattt
      121 tcttttagcc atagtctaac tctacttaca gcaagattag ctgcctcttt ttttggataa
      181 ccaaatacac ctgtagaaat tccacaaaaa acaatatttt ttatttcatc aatttctttt
      241 attgtattta aacatgattt ataacaatga agcagttgct tttcttgctc tttacttggc
      301 tgaccaccag atacaatagg tccaacagta tgtactacaa attttgcagg taaacaataa
      361 cctctagtta tcttagcatc tccagtatat tctaaatgcc cttgtttttt tattattttg
      421 tcacaatctt ctctaagtct aggacctgcg catgaatgta tctcattatc cacgcataga
      481 tgtaatggtt gtaaacaccc taataacttg ttatttgcag catttactat tgcatctgct
      541 cttaaattcg ttatattacc tctccatatg gcaatccctt cctctacttc ttctatatca
      601 tttacatcta ctaactctct ttcttcacat tcaatcaaca ataaattatg taacatatta
      661 agtatctctg gagcaatttc ttttggtgga tatacattca aaagtcctct aagtatatct
      721 ctaggcttaa tttcatcatt tgataaattg tatattttag aaggaacttc ttttgaaaaa
      781 tatgcaatta aagtgtttat attttttctt ctttgttcgt cagttagagg cttgatagtt
      841 ttatcaaaat cctcaaataa atttacatca tcagcataat ctctccactt catagccatc
      901 tctccattct tgtattttag acttaaaaat aattatgtat ttatgtacat atttatttat
      961 ttctataaac acctacataa atcctgttaa aagtgtaaat tttttattat acaacttctc
     1021 tggttatttc tattgattga tagtaaatta ttgtacctaa atttaatcca actaacaagt
     1081 aactaaacct actttcctaa ctgcaaaata cactatgttt gccacttgta tctcatttgt
     1141 agataaataa agtccctaca aatacattaa ctaggctatg tactaaactg taggaacttt
     1201 aaaaatatat tattcttaat taagttttgg ccaataattt ttatttgctt ctattaaatc
     1261 atctagtaat tcttttgcaa ctgttgcact aggaactgtc ttagatagca taagtgcttg
     1321 ccacaattta ttataagact tctcaatcca agcatcaact actaattttt caactgctaa
     1381 ttgttgttct attaaacctt tttggaatgt tggtattttc cctattgata atggttcata
     1441 cccgtctttt ccaactatac atggaatttc aaccatagca tcatcttgta tattttctat
     1501 agctccatta ttttgaacta tcaataacat acgctcctgt gtattaaaag ctagagctgt
     1561 agctaaatcc actataaact ctgcatgtat tcctatctta agcccactgc ccttagaatg
     1621 tccttgcttt tctatcaatg cacatgaacc aaaaacttct ttttctcttc catcaataac
     1681 ttcattggca cgagtataat ttacatcaga atgatttaca acataatctg gaaatagata
     1741 gtactttaag taactacttg gtattgtagt taaatctgtt tttactattt ctttagtaaa
     1801 taaattagtt tcaaaccaac tatctttctt gtcatttttc attccttctt caccatttat
     1861 aaaaccatat tcttttatat gttctactaa ttttggtaaa agttcatttc cttttttatc
     1921 tttaattgaa gtataccaac caaagtgatt taatccaaag tatcttatat ccatatgttt
     1981 acgagatttg agtcctgcaa tccttgctat attatgttcc atacctattg gcatatcaca
     2041 aatatttatt accctagaat taggtctcaa ccttctaaca gcttccgcta ttattgatgc
     2101 tggattagaa taatttaaca tccaacaatt tggagaatac ttttccatat aatctatgtt
     2161 ttcaagaaca ccttctatag acctcattcc ataagctatt ccacctggtc cacaagtttc
     2221 ttgaccaact accccatgtt ttagaggtat cttttcatct agttctctca tttcaagttt
     2281 tccaactctt atatgagcta aacaaaaatc tacatctgta taagcctctt tagggcatgt
     2341 tgttgctaaa tactctatat tagggtcctt ttcctttatt agtatttcac aagctttagc
     2401 taccttattt tgtctttctt catcattatc atataatttg attgctctta atggtaacct
     2461 atctaagtta tctagcaaca ttaatatgat ttctggggta tatgtacttc ctcctccagc
     2521 tattactact gaaaattttt ccataataat atctcctttt ctatttaaaa atttactgta
     2581 tttataaata aatttataaa tactagtact ttaaagtaaa agggagttca tttattaaat
     2641 ctattgattt aataaactat agccaaactt caagcactat ttacaagaaa tttaattctt
     2701 attaattctt gggtccatca tctcaaatat atctacaagt tcagatacta aagaatgagc
     2761 aaataatgca tttgaataat ggtcttcaga gtgcacaact aaaaaatcag tcccactatc
     2821 ttcactattc atagcatttg atagtaattc taaatgatgc tttgatgctg tttgtatttt
     2881 ctctgaggct gaatttaaaa ggtgttttgc tttattgtag tcaccttttt ttatttcctt
     2941 aagagacatc attacatcac ttttagcatc tcctgcttct gatattatac taaatacttt
     3001 ttcttccatt tcaggtacca tatccttctc cttctaatga cttgttaaaa atcaaagcta
     3061 tcatcatcta atgttgtagc taattctgca tttttattta attcttcctt ctccattatc
     3121 ttaaagaatg gataatatat caaggtcata agtattatac ttgcaaatac taatacgatt
     3181 gccttccaat ctaatgtcat caaaaatgct gcaacccctg gaggtaaaaa gcctggtggt
     3241 tctgcaatag gtaatcctac taatcctact tttaatgcca taaaattaag tgctccaacc
     3301 aatacaggtc caaatacaaa tggtacaaac atatatgggt tcataactat tggtgttcca
     3361 aatattaccg gctcatttat tccaaatagt gatggtaaaa tcacaacttt tcccatacta
     3421 ttaaaactct tacacttact tcttgacata aggtacacta atcccaaagt tattcctgaa
     3481 ccagttactt gcaagaaacc atagtaaaat cctattgtaa acacatattt tgggtctcct
     3541 cctgctgcta tcagtgttgc attttctgcc atatatgtag ctgctattgg catccatata
     3601 cttgaagtta ttgctgctcc atgaagccca aagaaccata ataattgagt tataaatagt
     3661 attatagtta ctgcaaaaac attatctaca ctgcttatag ctggtgctaa gaaattcatt
     3721 ataatagctg gtagtggttg acctgagaca tttttagtta ttgctgctat tgctgtaaat
     3781 aacattatac atactatcat tggagttaaa tttctaaaac ttttatttac tacactaggt
     3841 acttcttttg gaaatctaat tacgagattt ttatcattca taaacttagt aatatcaact
     3901 actaaaagtg ctactaatat acttacaaat aaaccttgtg catctaaata acttgtatct
     3961 aatacaccat ctactacttg tccacataca acaagttgtg caacaactgc tgtcatgcct
     4021 atttctacat gattaagatt atatttttta gctagtgcct gagctataaa aaatgctgaa
     4081 tatatagata ataaactcat agtaaattta ttagggataa gtaatgtatc catattttca
     4141 gataataatg tttttgcact tccttcaggt aacatattgt ttaatgccat aaataacata
     4201 cttaaagaac caacaattat tattggggta atgcttatca taccttcttt tatagcttga
     4261 agatgccttt gtttttcaat cttttgtgct attggaagaa gaaatcttct taaattattt
     4321 tgaagtgctt ccatttttat tccccccaat tatctatttt tatataattc gattgccgac
     4381 ttcataacag aaggagcatc catacgacca taatgcttag tatctattaa accaactgct
     4441 attttgtaat tcttacaagc ttcaactaca tcatcttcct taaacctaat ttgtggtgct
     4501 acaagtacta catctgtatc attagcttca atgtatgatt ttaaattttc aaatgatgtt
     4561 gcctctatat ttatagtttt agtttttaac ttttcatgct cactacaaaa acttttcatc
     4621 ttttccacaa gtacacctgt tgaagctcca tttgcacata ctaataaaat attcataatt
     4681 accctcctac aatatctaac ctcttttatt ttctaatttt ttatcagcca attcttactc
     4741 taattcctat cagtttttac tttaattctt attattttat tttaattctt attaatattt
     4801 actctaattc ttagtactgc caatgattaa acttgaaagc cgtatctata acttcttctt
     4861 gcttatattt ttctaatatt tttaagtatc tttctttata atcattatct acttcttttt
     4921 ctggtattac tatactagct tcatttaaaa agtggaatga atcccttccc atttctaatc
     4981 ctctatatgt atgcttgtca agtgccacgt ccataacttc tggaacttta cccattgcaa
     5041 atccttttat aattatattt tttaataaat cacttgatct atctttctca catgcacaaa
     5101 gatatcttat tgcatgtatg aaaaataaag gtctgtctcc atctgcatat gaatattcct
     5161 ttcttacttg atttaaatta tttatgatta ttacagctga tggatccccc attcctatat
     5221 cttcaactga tattgtaagt atccttctcc atagcttatc ttctaattct ggtgatgata
     5281 tatatagttc ataagcaaat tcacaagctt cttccaccat atttcttctt atagcttttt
     5341 gaaatgacga tattatttcg tctgcactaa atccgtttct tgtagtcatt cttgcccatg
     5401 ggtcatttgc ctttttatct cttaatattt tatcttgcat attatttact cctttttatt
     5461 taaattttaa ttatttatat tactcattta ataatataag caagtattat gccagttttt
     5521 ttagacactt taaaacactg ttatttcaat catttttatc atcaaaactt agatactttg
     5581 tctaagtata tttatatgtg tctaatatta atattatttt agactaaaaa aaaattacca
     5641 aataagtttt tatactcatt ggtaatcttt ttcgattatt tctgcatatt ctaatattaa
     5701 taatatttga tagcactctt tttcattaat ttctatatta tattttttat ctaattgaga
     5761 tactatatct tttattttgc ttagactctt gtgataatca agtgtttttt ctttatcaag
     5821 cttttcaatt tctctagtat ttccaatcaa cccatctacc atgaaagcta aatgcatcat
     5881 aagtccaatt actttatcgt atttcttttc tatattaaat actaaaaaca attcatcaga
     5941 cacatatttt atatctttaa atattctatt ataattagag ctttttaagg atgtctttaa
     6001 accttcaact acatcatcat aacctatact tatctttata atatttttta atttattgat
     6061 attttcatcc ttatctatat cttttttgct aatatagtca attcctctaa tattaattct
     6121 ttgttcattg attactgcaa caatattact actttcttta agtttcgtaa tatttaaact
     6181 taaatctttt tctgttttat atgggacaga tataatatct attccatcta agtacctact
     6241 catcttttct tctaatattt ttcttgtttt attatctaca ccttctgaaa catgtgatgc
     6301 tataataatt gttttagaca gattttcttt attttgaatt tcattagttc caaaatagtg
     6361 ctttctcgtg ttagtgatag agttgtatac gtcatttaaa ggtaatccca tattggcctt
     6421 ctgaactgct tctaacacag ttaatgtcgt caccatagga attactctta ctccacactt
     6481 tttttctttc tttataattt catcaaagga gtttaatgaa cccatatctg taaatagtaa
     6541 tacatcttta ttgtctatat tattaattaa atttttaaaa tctacaataa cttcatcata
     6601 gcttttatct aacttcatat cgaaagaaat agcactgcac tttccaataa tatcaccaac
     6661 tgcttttacc atactacttg ctgtagtttc tccatgcata gcaactataa tattaatgtt
     6721 attcactatt ttattttgtt catcttgttt agcttgtact atgaataatg taatatatgc
     6781 tacagtttct atagataaaa ataaatcaaa ttcattttca attattccaa ctatttttaa
     6841 tgctgtttta aattcacttc tgttatttct tctaatttga ttcaaatcta tgttgtttgt
     6901 agagctactt ttatccaata cgctttttat ataaattgcc attgacttaa atattgattc
     6961 acttatgtct atttcttcat cttctttaat aatttgtctt attgattcac acatgctttt
     7021 aaacttaaca ttattaaata gagaagcatc tgctatattc atttctacag atttattaag
     7081 attagtattt actgcattaa taatatttat atcattgtag ttaataactt cttcttctcc
     7141 taatgacgta aatacaaaat attctattcc atgtgttata acttcatctg ctttaataga
     7201 cttctctcta taatcatcac tcacttcatt tatagattta tcaaaatatt ttttctctat
     7261 ataaactggt tctttattat ctcttttata tcttagatat ccatttgcaa cagctaattt
     7321 tatatcattt tgaagttgac ctacattatt tttacaatca taaagtaata gtgatttaat
     7381 tatttcttta tgtactttta ttgaaataga aatacttttt gattcttcct tgaaaaaatt
     7441 tttgactaat tccattcttt caatcattgt cctatctctc aatgatggta tttctatttt
     7501 cattggtatt cttctattga atgtatctaa tagtgttgat gtcggatttt ctgtagtagc
     7561 acatattatt aataccttag actctctttc tttcgttgca tctcctagtc ttttaaatgt
     7621 tcccttatct ataaaagtaa acaacatttc ttgaccttct gctggtagtc tatgaatttc
     7681 atctaaaaat agtatccctc catttgcaat ttccaaaaga ccttttctgg aagattctgc
     7741 acctgtataa gctccttgtt ctaccccaaa aatatgtccc ataagtaatt gtgcattatt
     7801 agcataatca gcacaattaa atgttacaaa aggagcttta ttttttctaa ttccactatc
     7861 tatagaataa tcgtacatat atctagcaat catactcttt cctactcctg tttctccata
     7921 gataatagta tgaagtccat ttgtaggata gagcattgcg accttgcatt tttctattat
     7981 aggtcttaaa ctatgttctt tacctattag tgtttcaaaa ctatcttttt ttattttgtt
     8041 ttctactttt gttccttttt ttatgccaag caactcactt tgtgtatcaa gcaattcatt
     8101 cttgttaagg ttaagatttg cagggatata atacacaggt cttcctttta tcttcgtaac
     8161 cataccctca ttgaataatt ggtttaaata tgtacttata ttgtttcttg caattcctgt
     8221 cttttctgat aattggttag ctgtaatccc tttttcattt tccctatatg atgattctaa
     8281 aactttcatt actttatctt ttttatatat cattacaagc tcccctacat tatagtattt
     8341 tattaactaa aacccctata cacactttat tttttaataa actcttattc tttaactaag
     8401 gttataattt atcaaacttt ccttacttta aattatagaa aattattgta gaaaaaataa
     8461 gattattgct cattttttct acattactat ttttaatttt atagtacttt cttaacaaca
     8521 tactttactt gtttttaatt ttattatatt tgaatttatt atatttgaaa agtagaaata
     8581 aaaaacccta ttttggagta gttttaaaat ttctccaaaa atagggtttt agtttgtatt
     8641 tcaaataaat acctgttcaa gtatttttat actaaacaac ttttaaattt tgttgatatt
     8701 tatttatttc tgatttagaa gaatatacaa aatgtccatc tgaaacctca atccaactta
     8761 atgacttttc atttgaacaa tcatatccat tagaattata ctctattcta tttcttgact
     8821 tagcatatct agggtcagga acaggaattg cagaaagtag tgattttgta tatggatgaa
     8881 taggattatt atacaattca tttgaatctg ccaattctac taattttcca ttatacataa
     8941 ctcctatacg gtcactaata tgtctcacca tagataaatc atgagctata aataaacaag
     9001 ttaaattctt ttcttgttgc aattttttaa ataaatttac tatttgtgct tgtatagaca
     9061 catccaaaga agctataggc tcatcagcta ttataaattc tgggtctact gaaagagctc
     9121 gtgctatgcc aatacgctgt ctttgtccac ctgaaaaatc agatggatac ttatttgcat
     9181 aacttctatc aagtcctact agctttagca tctcatatac tttattcatt ctatctgttt
     9241 tatttttaca gataccttga atttttagtg gctctgaaat tatatctgca attgtcatac
     9301 gtggatttaa tgatgaagta gaatcttgaa aaataatctg catacttttg tttacatctt
     9361 tttttataaa tttgtacgtt tttttatctg atatgcaatt tcctttgtaa attacttctc
     9421 caccagtaga ttcatgtagt cttattatag ttttaccagt tgtagatttt cctgaacccg
     9481 actctcctac caatccaaat atctcaccct tatatatatc aaaacttata tcatcaactg
     9541 cttttacagt agtacttttg tccaaatgaa aatattgctt taagtttttt atttccagta
     9601 ttttttctct attcattaga aatcaccctt ccacaattta ctctaactgg tacatctact
     9661 tcaggtgcat ctgggtgcaa taaccaagtt gctgcactat gtgtatcatt aattttaaac
     9721 attggtggct ctttttcata atctatctta agtgcatttt tattccttat tgcaaaagca
     9781 tctccttttg gtgggttcaa taaatttgga ggcattccag gtatattata taaatagtca
     9841 tcctgcgaat ctaaagtagg taatgaaccc aacaaccccc aagtatatgg atgtctaggg
     9901 tcataaaata tatcctctac agttcctatt tctacaatct ttcctgcata cataactgct
     9961 attctatcag ctatagttgc aactactcct aaatcatgag ttataaatat tattgacaaa
    10021 cctattttat gttgtaaatc ctttattaaa tcaattattt gagcttgtat agttacatct
    10081 aaagcagttg taggttcatc agcaatcaat acatctggat tacaagcaag tgctatagct
    10141 attactatac gttgtctcat tccacctgaa aaatgatgtg gaaattgttt aaatcttttc
    10201 tcaggattat caattccaac caattcaata agctctatgg ctctcttttt tgcctcactt
    10261 ttacttatac cttgatgaat gattacagct tctgcaattt gctttcctat tgatatagtt
    10321 ggattgagag atgtcatagg gtcttgaaat atcattgata tattctttcc tcttatatct
    10381 tccatctctt tttcagactt cttaaccaaa tcacttgatt taagtaaaac ctctccattt
    10441 ttaatatatc cattgtatgg gagtatcctc atcaaactct tacacagtac agatttccca
    10501 caaccagatt ctccaactat agccaatgtc tcaccttttt ttagattaaa agatacattt
    10561 cttacagcct gaacttctcc ttcttctact ttaaaactta cagatagatt attaacctcc
    10621 aataaatgtt ccaaaaacca tcaaccccta tgctattcaa accttaggga tatattttta
    10681 tccctaaggt ttctaattaa tttcagtatt attcaattgt ccagtcagct atgttccaga
    10741 atacacctac accatgatga cctaaaactg tatcaggtgt taatcctttt atgtttggtt
    10801 ttccaacata tattgcatct atataagcaa taaatgtata aggcatatcc ttagtcattt
    10861 ctacttggaa ttgtttatat aactttaatt tttcatcttt atcttctgtt tctcttgctt
    10921 tttgaagtat tttatctata gtaggattag agtaagcact gtaatttgca cctttatctg
    10981 ttccaaatac tttatatgta tggtcatctg ggtcaaatgg acttccccaa cctattaaat
    11041 gagcatcttg attagcccaa tctgtttcag ttacaacaac agctttagca tcaacaccaa
    11101 tttcttttaa ctgttgtgca catattttag ccatatcaac tctaacttgg tcactctcac
    11161 ctgctgttat ctcgaaagct aacttagtac cttctttttc atagattcca tcagaaccta
    11221 atttccaacc tagcttttca atttcttgtt tagctttttc tggattatat tcaaactttt
    11281 ctatatcagg attattatat ggtcccattt gtaaaggtga atatgctggt acaccatgtc
    11341 ctaataatac actgtcaact attgcttttc tatctattgc atagcttaaa gcatttggta
    11401 atcctttagc ttttttatct ttaaagaatt tagaattaaa attgtataat atacctctat
    11461 agtcggctgt tttcattata tttactttaa aattcttttc gtctttttca aagttagaca
    11521 tatctttagg agttatttga gctaggtcta attctcctga ttttaattgc attgccttag
    11581 ccttatcatc tggaacaatc ttaaagacta ctttatctaa tcctggttct tttacaaaat
    11641 aatcactatt cttaacaagt gttatacttt gacctttgtc ccatttttca agtttaaatg
    11701 gtccagtacc tattggtttt tgattaaatt catcagtagc tatatcctta ccctccaaag
    11761 catgttttgg taatactcct actgttaaat aatcaagcat tgctgtattt ggagctttta
    11821 aagtaatttt tatagtatta tcattaacca catcaatttt tgttatatct tcataatttg
    11881 atgctatctc agaagcatta tctggattca ttatagtttc tattgtaaac ttaacatcat
    11941 ttgctgtaaa tttctctcca tcatgccact taacatcatc tcttaaatta aaagtatatg
    12001 tatttgttgc ctcatcaaat ttccagtcct ttgctagaca aggaaccacc ttattatttt
    12061 catcatgagc tgttaatcca ttaaatatta acgaatttat ttctccatgt tcatatagtg
    12121 caggatttat acttgtatag tcattacttc cataaacaag cacctttcca tctttaggcg
    12181 tatctgcctt cttatctttg tctcctccac tagaacaacc tgccattaga ctaagtatca
    12241 ttactaaact taaaactttt aacttcttta atttcatgat gctccccctt ttgcttttta
    12301 taaaatattt ttcaaagctt tgaccccatt tatttaaata gatatttcaa atacctcagt
    12361 atttgcttat ttaatactca aatgctgatt tataaattac tagatttttt attattattc
    12421 tttcttatat aattacctat atttgttata cacaccaatg tggtaaccaa aaatataccc
    12481 ggaatcagta taatccacca tctatttgaa agtaatgctt cctctgacaa agataacata
    12541 cttccccaag aaacaatttc tattggtaaa ccaattccta aaaagctaag tgtcgattca
    12601 gtaccaatag ctgcgcctat gtttgttaca accatgaaca ttattgatgc cacaaaattt
    12661 ggaagtaaat gttgctttaa tacatagaag aatcctcctc ccatgctctt agctgctagt
    12721 atgtattcgc tattttttat ttgtctaact tctgttctca ctatcttaga tatattcatc
    12781 caacttgtta tccctattac tatggacata gatactggat ttgaatttcc aagtatagct
    12841 tgtacaaata ttataattaa tattgaaggt atactaagta tgatttctgt aaacctcatc
    12901 attgcatcat ctacgagttc agatgccgaa ccacttatac taccataaac aattcctata
    12961 acagttgata ttacagtgga aaatagtcct ataaataaag atatttttcc tccataccat
    13021 atcatagaat atatatctct acccattgag tctgttccaa ataaaaaagt tttatttgga
    13081 gctaaattag aacttgctaa atccatgtat gttggttcat gtgtcattat aaaagatgag
    13141 aatacacttc caatgactat gattgataaa ataataattg atatatatgg taattcttta
    13201 atttttttag ataaggtttt ctttgtttct atatgttcat cttctgctac taaaatataa
    13261 ttttctccta caatttcaaa atcactatat tgtggcttca ttagtatcac ctctatcata
    13321 tttcattcta gggtctattt tattgtttat aatttgagct aacatattcc caaatactac
    13381 taaagcccct gttattaagc ataaaactaa taacatatta taatcatgat actttgcact
    13441 ttcaaaacaa agtgttccta acccaggata agaaaaaact ttttcaacta cataagttcc
    13501 tcctagtata tgaggtatcg aaatggccat tatactaata tatgatggca ttatatttct
    13561 caggcaatgc ttaaaaacaa tagttctatt atttaaacct tttgctttac ataaaagcac
    13621 ataatcttct cttatttcct ctagtaattt atttcttatc atatatgtgt aataccatag
    13681 atggcttaat ataagtactg taagaggtaa gattagatgt gatatcctac ttaatatact
    13741 ggactcttct cccattgaat aagcaccact acttggaagt atacttaagt ttatactaaa
    13801 tataagtatg agtactaagg caacccaaaa tgatggaata cagttggtta ttgttcctaa
    13861 tttgcatatg attctatcaa tgagcttatc ttcatgtaat gtacaaaata ttcctaacaa
    13921 taaggctagc acaaaggtaa gtatatatcc tgaaccacct aatattatag tgtttatata
    13981 gacatcattt ataacagaag taacattttg tttatattta aatgaaattc caaattcccc
    14041 ttttgatgca tttgaaatcc attttatata ttgactgtat attggttcat ccaaaccaag
    14101 ttttttcata gcattttctt tttcttgtgt actcattctt tctactccat ccccatagta
    14161 agagattaat gggtctcctg gagcaagtct tgccatgtaa aaaacaataa aagataataa
    14221 aaacattact aaaataaact gcaacaactt tttcagtata tcctttaaca aaccccaacc
    14281 cccctttgtt gcaataaaaa aaaccacata aaagcaaacg taaagtaacg ttaaaacctt
    14341 cgtggttcca ttatcattaa acaaaattaa attttctata tttatctatg agttaatttt
    14401 agcatcattt attaactgtg taaacaaact ttttaaaaat tgttaaaatt tcatcaaatt
    14461 attttattta tacctaaaat aaaattttta tattctattc ttcattattt tctataaaat
    14521 tataaaattt taggttgact atataagaaa agtatattat attagtttgt atgcaaacca
    14581 tttaagaggt gattttattg aaaagtaatt atgactgttt tagaatagcc atgctcttaa
    14641 aagaacttta ttctaaaact atgtacacag tagaagaaaa ttttaaagaa aatggattaa
    14701 cacaccaaca gattatagtt ataaaactga tagctcataa tcaagaactt acaatatcac
    14761 aactatgtga tgaaatgtct ttagctaaag gtacggtttc aggcataatc agcagattag
    14821 aacagattgg atatatagaa aaattcaaga aatctaatga taaaagaaat acatacgtta
    14881 agtttacaac aacaggattt gaatttgcca caaattttaa aattaaaatg caagaaagtt
    14941 ttgatgatat ttttaaaaat tgtgatgaaa acgaattgag tgacttagta aaaaatctta
    15001 gaaatatatt ggcaaaagta aaggagagat aattatgaat tataaattaa tacttgcaat
    15061 agtatttata acatcagctt taattttcta cactataggt gtatttggag aaagaaaggc
    15121 aaaaatttta aaaaagaaac atgtaattat attttggctt ggttttatat ttgatacttt
    15181 aggaacattt acaatgagta acatagccaa cagccatact tttgaagtaa aatctgcttt
    15241 atcacaaaac cttcatagta ttacaggtct tcttgcaatt gtgcttatgc tttttcatgc
    15301 aagttgggct acttttgtcc tatacaaaga tgatgaggaa aagaaaaaat tctttcataa
    15361 gtttagtata gttgtatgga ctatatggtt agttccatat tttataggta tgtttattgg
    15421 tatggctgga tagtaaaata aaaagtgtgt aagaaatact gtaggtaaat ttgtataaga
    15481 caaatttatc tacatccttc tttcacactt ttacatattt atttataata ctccattatt
    15541 tctttcatgt ttcttaatac ctatatagaa tatttaatta tttctatagt attttattat
    15601 tttctcacac tttttcatat atatattgtt ttactatttc ttcatatgta tatatgaaat
    15661 attccattat ttctataaat gttttattat ctttctcata ctttttcata tatatattgc
    15721 ttcactattt tttcttattt cttcatatac atatgaaata tttcattatt tctataatgt
    15781 tttattatct ttctcatact ttttcatata tattgcttca ctattttttt tacttcttta
    15841 ttaaatactt atgtataaca tacatttaat aaacgctaac tattaaacac ctaatacttg
    15901 agttactcct ggaacttcac tcaccaaaac attttcaata atagctttga ttgtcatagt
    15961 cgctcctgga cacccactac atgccccttg tagtctaact aaaaccacac cattttcatt
    16021 tacatctata agctctacat ctccaccatc tctttgtaat actggtttta tcttttcctc
    16081 aagcactttt tcaacttttt ctctcatagc tattcccccc agaaatattt tattagcaaa
    16141 attataccaa tggtttaaat ttttgtccat ctaatgattt atcaaattca atttttgctt
    16201 catcaataat tttagtatcc ataaatacat cataagcact acaagccagt actttagctg
    16261 aatttatcat agcagaaaat cctatatttg aacctgctga tgaacatgac tgccatgtat
    16321 gacttgcaat tccaacaggc caagctgcca ttgcaaattg agccactggt attacataac
    16381 ttacatctcc aacatcagta gaaccagcta gtcctttatc tttgtcaccg tcaactattt
    16441 ccttgtgtat atagctttct acaatagatt tatcattttg taatgatgtt gctacaccta
    16501 atctttcttc tctagtaaga gtatcacaca acttttttgc aaattcttct tcttcaggag
    16561 tatttttagg gcaaccaaca aaaaccatat tgtcataaac taaatcagtc aaacattggt
    16621 ttggtatata gtcatatatt ccatctgtaa ccttatactc catttcagtt tctgtcatca
    16681 ttgctgctcc ttgagctact tttattaatc tatcaagaac gtgttctgca tcctttgctt
    16741 ttttacctct aataaagtac caactttcag caaatccagg aactacatta ggtcttccac
    16801 caccattagt tataacatag tgcattctta tagagtcaat aacatgttct ctcaaataat
    16861 tagctccaac attcataatt tcaacagcat caagtgcgct tctaccatta tgaggagctt
    16921 gagctgcatg ggctgttatc cctttaaatt taaattttac agataagttt gccagacttc
    16981 cacctctcca aggtgcattt atatcaaaag gatgccatgt aaatgcacaa tctacatcat
    17041 caaaacagcc atttatacac atagctgtct ttcctccacc ttcttcttca gcaggacaac
    17101 caaaatattt tattgttcca ttaaatttat tttcttctat taattttttt atagaaacaa
    17161 ctgctcctac acctgctaca cccaacaggt tgtgcccaca tccatgtcca gcttttcctt
    17221 ctaccaatgg ctttctttct gcacttacac attgtgatag ctctggtaaa gcatcatatt
    17281 ctccaagtat gccaatcaca ggtttaccct ctccaaaact tgctataaat ccagtaggta
    17341 aattttctac ttcttcaatt ttaaatcctt ttgactttag gtattctttt tgaatgctac
    17401 ttgcatactt ttcttcaaag gctaattctg gattttccca tattttctta gataaatcaa
    17461 ttaattcttc tcttatttct tcaacattat ttatgatata ctctttcata attttcctcc
    17521 aaatatatgt atttttgata tgctttacag attatattat atactaacat tctatttatt
    17581 cacaattttt tgttaattaa ttttattcat atgctcttct atggagtata tcttatcttc
    17641 actttgcctc ttcataaatt taatgtactc tatcttccat aaagtagttt cagttttctc
    17701 atttaacata aattctaata tattaatttc tctcattcta atatcttcat aaaatactac
    17761 actacccaat attgccaatt ctaattcact taatgatgca aacaacatta aatactcttc
    17821 tccaaataaa cattcagatt caagaatatc gataaagtct tttttagcat tgatattttc
    17881 ctttattatt cttatttttt caattataga tgtactatct aatatctcat tgaatatctc
    17941 tctaaacgat tcatcatcca atttactttc atcatcaaca atataatctt ctaagtgttc
    18001 ctttttattt ttactcacag ttaccatact tttaaaagtg ttacttttta ttgagcttag
    18061 cacagattca ataaatatct tttcatattt tttaatatat cttattacat cttcatcttc
    18121 tatgcttaat ctttttatta atacttcaat tgcttccata agtagtaaag ttattttttt
    18181 atttattcta atttctctgt taatttcttc aaaatcatta taatccaaat tactatctac
    18241 ttcagtgtta aaactatcat ctacttcaat caattcaatt atattacttt cttcagagtc
    18301 tataacttta tcttcagtaa tattattgta catattttta aattgttttt ctaaaaattc
    18361 atactcatat tttgaaattt ctaaattagt cacttcattt cctaaaatag tagaaaaaat
    18421 acaattattt ataataagtt caaataaatt tacaagtata gcatcacaat ctattttata
    18481 agtcacccca tagtcataaa ataatttttc tctatctttt ttcttaaata ggttacaaaa
    18541 tctattttct atatctatac tctcaatata attcttcaca taataaatac ccttaacatc
    18601 catatcatct agtgccaatg gataatctat acttactgga acgtcctgag cttcaaattt
    18661 tacaatataa cttttaaaga aacttgataa ctccatcaag gtatcattat atgctattga
    18721 attagtatcc aattttctac tcatcattag tttataaaaa tcttttagcc taactaactc
    18781 ttcctctaat atttcaatgc ctccaaggta cactttttta acattcttag cagtcaactc
    18841 cacaactctt ttttctatat ccccaagctt atttatatat gcatcaatag cataccatat
    18901 tgaaatcaac agtttttcgg caacttctgt ttttactgat gtgctttgac catttgtata
    18961 ttttttaatc aaatccataa gtattagaga tatttcttgt tgtatattat atacttctct
    19021 ttcatctatc actttacaat ttagacattc cttaagtaga gatatggaat attggttctt
    19081 tattaaatta ttttcgttta tattaatatt acttaaatta tttaacatac aaaatctctc
    19141 ctatcatata ttaaacttct ccaaatttaa atttctttgc aaattcgtct gcttctcctc
    19201 ttacattgtc catattgcct gaaaattttt cataaaattc acccagtatt tctataatct
    19261 catcatcaca tatcttgtca tcagtttcat tttttaaata ataaaaaatt tcttgcatat
    19321 cattaatagc ctctaaataa ttgtccacat ttgtatattg tgatgtatat atattttcta
    19381 ttaactgttt tgtaactttt atatctaatt ctattcttcc ataccccttt aaagtattat
    19441 ctctcgaatt tattatatct tttacatcag attcagaaag agctagacca taatctccag
    19501 attctatatt agtttcaagc agttcatttc tttctatttc ctttaaattc tgatttatag
    19561 aactcaaaat aataggtgat atcattttta aattctcctt ttttattttt tccattgact
    19621 ttttttgttt tttatgctat acttaaatta atttatatta ttttaccaac cacttataat
    19681 agtagtgtta aaagtggttt ttgtcaactc aaaattacta tctcaattaa acttttcaat
    19741 tttctcaaca aaaaaatacc atcatttaga tatataactt tctataacaa cttttaattc
    19801 agtagttatt tactaaaatc taaacaatga tatatttatt aattttattt atcttttttg
    19861 gctctacttc tacttttctt tacatttgag caatttctac aagaaggtga acagtattga
    19921 gatttagaat ttgtaggaat ataaatttta ccacagtact tgcatttatt taaagaagaa
    19981 ggttcacttg taattgcaaa ggcatagata gtctcaatag ctgttttcaa agaatcaaac
    20041 tcccatgcaa taattggttt atctaattgg cttatagaaa atcctatctt ttgaggatta
    20101 aaccctccag acataatagt aacactttca gttaatagat tagatgtatt tttatataca
    20161 caaatttgat taaaatgctt acacatatct ttagcaaaac ttacaatcca atctagttgt
    20221 tcagtgtaga actttgaaaa tactaaatct aaaatcaatg gtctctttcc aaaaaacttt
    20281 ggagattctt ctctctttga tacatctata ccccttctat actttttaaa atacacatct
    20341 tcatcacttg caaatggtat aaacatgttt acatattcat ctgtactcaa tatattctct
    20401 tttgtaatat aattcttttc aatcatcagt actctttctt ctccaactat atctctatta
    20461 tatacacttg aatatattaa acccaataat ccatactttt ttacaaattc aagtacttct
    20521 ttctttagtt tcatttcttt tgtctctttt gatatatctt gtaatgcctc ttgtcctatg
    20581 cgaattatat ctactattat atcatctgct acatcaaatg ggttatacat ggtaaacaca
    20641 gcatcttctg ttggaactat atataattca tcttcttcag taattttata ttcataatca
    20701 ctatacctaa tccaatcact tgcaaaattc cctattaatt ctattttttt attcataata
    20761 atcattcaca cctttcaatg taatatataa tttcatatta ctattacact tttagtttat
    20821 tccatatttt ctacactgtc aactattctt tttatatttt tagcatatta aaatttataa
    20881 tagcctttat aatggatttc tagagctaaa tttcttgttt attgatgact aattcataat
    20941 taaatttata aaaactattt acatataaaa ttaatctctt tataattgat atgtaatata
    21001 tttttacact tacatattac atatcaatta taaagagagg tatctaaaat catggataga
    21061 aaacgtgaat taaaacaatt atacaaagaa atgaaatttg acacaggtgt attcataata
    21121 aaaaatgata ttactaaaaa gatttacctt ggaaaaagta atgacataaa aagcaaattt
    21181 aactctctca aatttcagct tggtgctggc tcatgtatga taaaagaatt aaataatgaa
    21241 tggaaaaaat atggtgaaaa agcatttaca tttgaagttt tagaacttat aaaacatgat
    21301 gataacaaaa cagagaaaga ttatttagaa gaactagata ttttagagat ggtttggtta
    21361 gaaaaattaa aggaagataa tacttatgaa atttattcca tataaaaaat catataatat
    21421 aagaaaagga gatagtatat caaaatagac atttagttca taagatactt ttttatataa
    21481 aataaagtat cttttcataa ttttaacaat gaaaaagagg cttatctcca tttgatagcc
    21541 tcttcccata tattttatac cattataaaa tgaacaatct actaattttc aatgtgtata
    21601 ttcattttac taataacact ccattacttc tttacagcat ccaaacattg ctctataata
    21661 ctcttatcac ttatacctat tgctgttact ttactagctc cacttaatat actcttatca
    21721 cttttatttg aaactaaaac aacaggagca ttttttgcaa gtggtgatgc aactaaagca
    21781 taaactaaat cgtctccact tgttatatag aactcttttg ctccattata gaacttttca
    21841 ataacatttt tattagtttg atatctatca acaccaccaa ttctagttgc tctatatctg
    21901 ctcactatgt aatcacttaa tgtagactct cctccaatag catatactgg aacaggagaa
    21961 actccaaacc atgggtctaa gtctgtgtct tcttctgctg aaggtatatc ttttgtcaat
    22021 attataggag ctccatctct ataagcaaca gatgcaacac ttactgcatc agcttcatcc
    22081 ttaaatccat ttactaaaaa catcttatca ctgtttttaa ttttttctat ttcacctgca
    22141 attttataac ttgtatctac tctatctaca ccatcaattc ttataacttg cattcttctc
    22201 ataagtaaca ttttttctac atctttactt atagaatttt ctccacctat tacatatatc
    22261 ttagtaactc tattcagtct ttgaagcgtt gcttctggta tatcatcctt attagttaat
    22321 aaaatagctg cattatttac tcctgcaaga ccacttgcag caatcccatc taccattgta
    22381 gaatctgcat tgataagaac tgctgttgta aaatcttgct tatctgaaat aagcccagct
    22441 gtttcatatt tatctactcc ttgaatattt tcaatcttat ctagtgcgtt tattgatgtt
    22501 ggaaaactaa cacttaacag taatgctgaa atacctaacg ccaatacctt tttactaatc
    22561 ctcataaatt acctccctaa aacaaatata tttagtatta gtataatata aaatcattta
    22621 aaaatagtgt aaaaatagtt acactttttt ataatttaaa taattttaga ttaaacacaa
    22681 ttcatccatt aaaataactt catttattct atatgctaag ccatcccacg ttttttttga
    22741 catatctaca gatgttttct tatttgagtt attcaataaa gattgtatct tagaatctat
    22801 tgcattatac aaattatttt caaaatcata taactcttca tcttttggaa taccttcttt
    22861 ctccataaaa ggtagagaaa catattctat ctttccagaa ttattaatct cactaccaat
    22921 ccactcttta acaccaagaa tatcagtagt gattacatct gtgccacaag ataaagcttc
    22981 taaaactaca actggtaatc cctcataaaa tgatggtaac acaaatattt gtgacctgtt
    23041 gaatagctca gctaaatctc tctgttctaa ctttcctagg aaattcattt taaatggaga
    23101 cttacttgcc agtttaacta tctcattata tgattcgata tcgcttccag tacctgcaaa
    23161 attgacttct attaaatctt tactatattt taatttagat atagctttta taaatggaat
    23221 cagtcccttt gatttacata tcttacctgc aaatactatt tttattttat catcctttat
    23281 tttataattt ttattataaa atatatcatc attataacca ctaccaatta caactacttt
    23341 actttgactt actccaaaag tctttataat atcatatttc tgattttcat gaagagcaaa
    23401 tattaaatct aatttcctta tatttgctat tatgtattct ttctctaaat caatggtatt
    23461 taactgtctt aaacaagttc catgacaaat agacataacc tttatatctt ttaccatttc
    23521 cctaacaaat gcagttaaaa ggtacaaatg atgacatatt ataagttctg gtttaaaatc
    23581 attcatagcc ttatctatat ttactttaaa ttgatatttc aatctattta tcatgtctat
    23641 atttaaatct ttatatcttg tactttcata tggcatagaa tcactcatac ctacaacagg
    23701 aaaatttaac tccccacaat tatactttac tggataaaaa cttacttcac ttggaaaaca
    23761 atttacatca tcatttacat ctatacctgc aattacagct tgcttatgac cgattttttc
    23821 gaatcctttt atcataccag acaaatatat accactacct gtactatttg gtttttgtgt
    23881 tattatatga agaattttca cttttcactt gcctcctttc taaaattaaa tagttttata
    23941 cagtctaatc attatatata tctaaatata aacaagatga atcatctttt actttaaatc
    24001 ttggcacttt aaccgcttta tagtcattat cttcaaaatc ccttacttta ttatgtatat
    24061 atcctatacc aaatttttct gctatacgta tcaattcttc ttcttttatt agattatatc
    24121 tatcacatgc acttgtaaaa ccatcactcg ttagcatcaa ttgaaaatct ttttttattt
    24181 caatgtatcc atatatagaa ttttccacag cttcctcatc aaaatccaat atccaatagc
    24241 cctcttttgt atttttcttc aatctattgc ttactattgt atccataaca ctagttctaa
    24301 tctcatcaaa tgccatctct tccaagttag aaagtttact catttcatca aatacagtat
    24361 tatcaaattt acaaatactc ctatctttta taactttgga atctccattt ttaataaaca
    24421 aagcacaatc tcctaataaa aaatactcta ctttattttc atgaaatttt acaacaacta
    24481 tagaactaga tggtaaatct aatttttcaa ccttaaaccc atttaatctt agttcatact
    24541 ctttttttac ttctattatt ccagtattaa taatactctt taatgattct tctttattta
    24601 tatttttata taaataccta ttccaccact gaacatacca ccttgcgtca ctttcagttg
    24661 acactaaatt ttttccatta agtcctgtag caccatctaa aacccatgcc ccaaatggat
    24721 ttataccgac tacatcttca ttaaatttag ctgttccttg attacataat aggctatagt
    24781 ttcttatatt taaagccata tcaacctcca aattgaatat ctaaaaataa agttctattt
    24841 aaaattatac agcaaataaa aaaatctaca acaaaacttg ttgtagattt ttacttaatc
    24901 tatattatct ttatactttc agtattttaa tgatggaata atctattctt agtaaatgcc
    24961 atgactatgt tatacttatt acaagttaat ataacattat catcacgaat agaaccacct
    25021 ggttgtgcta taaaacttac cccacttctt tttgcacgtt ctatattatc tccaaatggg
    25081 aaaaatgcat ctgaaccaag tgctactcct gttaaagttt taagccatgc tctttttcct
    25141 tctccagtta gaggctctgg tttttcttca aaaaagtttt gccatatgcc atcagcaagc
    25201 acatccatat aatcatcaga aagatataca tcaatagtgt tatctctatc tggacgacct
    25261 atatcctttt taaattttaa gtttaatact ttaggatgtt gacgaagata ccaagtatca
    25321 gctttgttac ctgcaagtct agtacaatga atacgtgatt gttgacctgc acctacccct
    25381 attacttgtc catctttagc ataacaaaca gaatttgatt gtgtatattt taatgtaata
    25441 agagctataa ttaaatcacg ttttgcacta tctgtaaaaa ttttattatc agttggaata
    25501 tcttttaata ggtcttcatt tattaatatt tcatttctac cttgttcaaa agtaattcca
    25561 taaacatcct ttgtttcaat aggttcagga gtataatttt catctatttt tacaatatta
    25621 tagttgcctt tacgctttcc ttttaatatt tcaagggctt catctgtata tcctggagct
    25681 attataccat cagaaacctc tcttgctata atagttgcag tctccttatc acatacatct
    25741 gaaagtgcta taaaatcgcc ataagaagac attctatctg ctcctcttgc cattgcataa
    25801 gcacaagcta atggagaaag ctctaaatca tcaacaaaat atatttgctt taaagtatct
    25861 gataaaggta cccctactgc tgctcctgct ggacttacat gtttaaatga agttgctgct
    25921 ggaagacctg tagcttcttt taattccttc acaagttgcc aactattaaa tgcatctaaa
    25981 aaatttatgt atccaggttt tccatttaat acctctatag gaagttctcc attcttcata
    26041 taaatctttg atggtttttg atttggatta cagccatact ttaattctag ttctcttgcc
    26101 atatactcat ccctctctat aataaattaa tcataagttt gattaatcct atattaatta
    26161 aattattcgt actaataaaa ttatatggca tatttatcca ttaatcaact atatttttta
    26221 aaactcctat tccttcgact ttacattcaa ctatatcgcc atgctttaaa tatacttgag
    26281 gattcatccc catagcaacc cctgctggag ttccagttga aattatatct cctggcttta
    26341 gagtcattcc tcttgataaa tcatttatta tagtaggtat atcaaatata aagtactctg
    26401 tattagaatc ttgtcttact tctccattta ctacactact tatatctaat tttaaaggat
    26461 gttcaaattc ttctttatgt actatacaag gtcccataga tgtatgtgtg tctaagcttt
    26521 ttcctctaaa ccattgaaca tgtttatctt gaagtgctct ttcacttata tcatttacta
    26581 ttgtatatcc aaatatatat tcataagcat cttcttttga tatatttata ccttctttac
    26641 ctatgattac tgcaagttct gattcatagt ccaacttctc taccaaatct ccatgtaagc
    26701 ttatcttatc atccactcca attattttgt ctgctctctt agaaaaataa attggataat
    26761 ctggcataac tacgtttttt ataactccat ctgggatttc attgacatgg tctttatagt
    26821 ttagacctaa acatataata tcttttttag gtcttacaat tggggaacat aatttaactt
    26881 cttctaactt ataacacttt gcgttttcaa atgaattgtt ttttattttt tctaaatctc
    26941 ctgtagatac gttttcaata aaatcattca tatcagtata taatttactt aatcctaaac
    27001 tattaatttc atatatacta tttgtttctg aattaaatac acctattttt tcttcattgc
    27061 tactacaaaa agtcacaaat ttcattttta ttcctccatt caataagttg attaatatta
    27121 tttaattttt attagtttat ataaattgta attcataata tttatatgtc aatacatatt
    27181 tatatatttt aaaaatattc aaataatttt tattaaattt attagttatt aatatataag
    27241 tgctttataa aacacaaata aaataaggtt gatttaaaat taaatttaaa acaaccttat
    27301 aaaccgatta tactatctac ctaataaata tagcaaataa gctcctcaat aatatacaaa
    27361 accctacatc tctaaaccta tacttaacta atccaagtac aataccaaaa acagtaccta
    27421 tcataatttt tgaaataata acttcaaagg tgtagcttga attgttatac aatattacat
    27481 aatttcttat aacatctatg tatcctatat tataaattcc agatagtata gatgttatac
    27541 agataatttt actctttgac tttataaaat tacttagata gttccatata tattctctaa
    27601 aaaataactc ttcaaatatt gggactatca atacagacaa agtcatcata gttacattaa
    27661 aaagtacata tcccttagta caataagtta caattattgc taaagataaa accacaacaa
    27721 aaagtatcag cttacacttt tcaataagta tattgttttt attttcttca aaagcttctg
    27781 tgatttttct atttctaacc ttgttataca aagaattatc ttttaaaaat aaaattaacg
    27841 ataaaccaac taatgtaaaa gaaattaagt ttataatatt aaaattttca agagtaaatt
    27901 caaattgact tagaagtaca taattcaaaa tcatccttaa tatttgaact ataaacatca
    27961 ataaaataga atctattatg cattttttgt aactatactt catcccaatt taaatcaccc
    28021 catgtatatg ctaatcgtaa agtccattta ataccctact tacagttgct ttgctccaac
    28081 ttgtttgatt tgaaatttct ttatagctta agccatctct tcttaaactc tttatattat
    28141 ttatatcatc atcagtaatt tgtttttctt ttggcttaag gctattttta tagcttctta
    28201 gtctatccaa ttctgatttc aaactatcta cctcaaactg ttttttttga agtttactct
    28261 cataagaatc tctcatttca ttaaactctt taatgtagtt tactttccag tcctcatcca
    28321 tttttgtttt aaatataccc atactttaac ctccttaaat tttgttactc aagttatgta
    28381 tcgattataa acattaattt ctatatttat ctttaaaatc cttgtacata acccctagat
    28441 aagttagtaa aattcagata tatttttaca attttaagta tatattaaca atagaaaaaa
    28501 atataatgtc ttaatacaac atattatata ctaaaagttg ttaaaatgaa cctttttata
    28561 gtctaaatca gagtcaccgt atgctttctt ttcttcatca ggatatccta tagaaattat
    28621 acattctaca ctgtacttgc taggtacttt taattcttct ctaatgtact tatcagcttc
    28681 tatattatca tcatgcattc tatttcttac ttgtatccaa caagaaccta aacctagttc
    28741 atgagcttga agttgtatgt atgaagcagc tatacttgca tcctctatcc aaacatcatt
    28801 tttttcttta tctgcaataa ttacaatagc taaaggtgca ttttttaaga aaaatccacc
    28861 acctttagtt ctacattgag ataaattaat tagcttttct ttatcatcta ccactataaa
    28921 ttcccatgtt ctaagcccct ttgatgatgg agctaaaaga gcagctttta atattttatc
    28981 taatttttct ttttctactt caacatcctt gtattttcta atacttcttc ttttctttag
    29041 aaatccaatc atataaatca tccctttcat aatagcatac actaggttat attatgccct
    29101 tactaatgct gaaaatctat tatttatccc ttgtattata aatgctcttt ataatatttt
    29161 atcataacag tagaaagatt tctcctttcc taaaaaactc atttctccga tttttataaa
    29221 accacacttt gtaagtaata aattcatttt tgagtttatt gaatatgtat cgctctttaa
    29281 gtatgataca ttgttttcta cagctaattt ttcagcaaaa tcaactaact tagatgctat
    29341 tcctgtcttt ctaaagtttg gatttacagc cattctatgt attaccattg cttttttatt
    29401 agatgaccaa tttaagccta aatattcttc tggctcttca taattaagac atataaaccc
    29461 tgctacttct ccatccactt cataaatata taaatcttgt ttcttaatat ctgaaacaaa
    29521 gtctttttct aatggatagt tttcatccca ttgtgtatta ttataagtct tcatttcttc
    29581 cactgtagat tttataattt gcataatgct ttctaaatca ttcatattcg cttttctaat
    29641 cataaaaata tctccttaag ttaatgtatt tatttactat ctctttactt taaaccattc
    29701 attttctacg tttttgctca ttttttctaa taacttagtt accacttgtt tttcttcatc
    29761 tgtaaaatta tcaaaacata tctctatact tctattctct tcttcaatta tcaactcata
    29821 aacttccaaa gatttatcag ttggagttaa attatatcct cttttatcaa acttatcctg
    29881 ctttttatct acatatcctg cctttattaa tttttgtata gccttggttg ttgtagcctt
    29941 gtctaccttt aacatatttg ataattccac aagatttata ccaggatttt cacagattct
    30001 tgtcaaaaat gtaaattgtc ctttttgtaa ctttaattcc ttgtacttaa tatcatttat
    30061 tgaatttact gctctagata aagtacctac ttctcttaat atattactat ctaaagtctt
    30121 aatcaaacac acctccactg aaactactat ggctaaagtc aaatagtttc tgttttataa
    30181 aatttcacat aatcaatata ttcattttta gttgaaagtt caactttttt aaattttacc
    30241 atattttggt tgaaagttca attaaaaata ataaatttat ttaatctttc tttgcatatt
    30301 aatcaattaa ttttaaaatt aaaatggata tcccaaaatt aactttttcg tttatgagga
    30361 actctctttt gtataaaatc aaatatattt tatcattcca ataaaaaagg cttatctcta
    30421 ttttgagaaa gcctctttcc ttcaatctat attttacttt ttccctaaat aaaatctata
    30481 caatatactt acacacctca tccgcaaact ctgtagtaga agctgagcca cccaaatcta
    30541 cagtcaattt acttccttca agaaatactt tttctaaagc tgtttctatt ttttgtgcat
    30601 tttcatattc acctaagtat ctaagcatca ttactgatga ttgaataagt gctgttggat
    30661 tagccttatt ttgacctgct atttgtggag cacttccatg aacagcttca aatatcgcac
    30721 aatctttacc aatatttgca cttggaatta tacctaaacc tccaacaagc ccagcaccta
    30781 aatctgatag tatatctcca taaagatttg gcattaccat tacatcataa ttttctggat
    30841 ttaaaactaa gttcatagct gctgcatcta caatcaaatc atcatattct acaccatgtt
    30901 ttgatgcaac ttctctaaac acatctaaaa acaatccatc agacattttc attatatttg
    30961 ccttatgtat agctgtaact ttttttctct tattatcttt aacatagtta catgcaaaat
    31021 caacgattct ttcacttgca cttcttgtta ttatctttat actttcagct gcataatcac
    31081 ctattttatg ttctattcca gcatataaat cttctgtatt ttctcttaca accactaaat
    31141 caacatcttc atatcttgat tttatcccct taaaactttt aataggtctt aaattgacat
    31201 acaaatctaa tgcctgtctt aaagttacat ttacactcct aaatccttta cctacaggag
    31261 tagtaattgg gccttttata gctattttgt tcttttttat actatctata atatattcag
    31321 gaagtggagt accatactct tcaataactg cctctcctgc attaacttct tcccattcta
    31381 tttctactcc agtagcttct actacctttt tcatagcttt cgcaacttct ggtcctattc
    31441 catctcctgg tataagtgtc actttataca ttcaatattc cctcttttca tattaattag
    31501 cttgattttt agtgtagttt aattttccac cagcttttaa tacatcaact tcttttgctg
    31561 acaattctac tttgacctta aaagaagttc ctttagttgt attcttaact tctaaaattc
    31621 cactacctag attgtctaaa atatttggta tctccagatt atctaaaaga gatatatttt
    31681 cataatcttt ctcatcacaa aactccattg gaattatacc actatttatc aagttagcct
    31741 tgtggattct tgcaaagctc ttaactatta cccctttaac acctagatat aatggtgcta
    31801 aagctgcatg ttctctactt gaaccttgac cataattatc tccaccaact ataaatccac
    31861 cattattgtc ttttgctctc tgaggaaatt ctgtatctac agtattgaaa caatagtttg
    31921 caagatacgg tatattactt ctaaaaggaa gtaacttagc atttgatggc attatatggt
    31981 cagtagttat attatcttct gtctttaata taacttttcc acctatagac tgacttagct
    32041 ctgtattaag agggaaaggt tttatattag gtcctctaac tacttctaca tcacttccta
    32101 catcagcagg tttaattatc atgctatcat ctatcaaaaa ttcatttaca tctaaatttg
    32161 taaatttaat atcaaattct cttgggtctg taagcactcc cttgattgca cttactgctg
    32221 ccacttctgg acttactaaa tatacttgtg ctgacaaagt cccacttcta ccatagaaat
    32281 ttctattgaa agttcttaaa gacacagagt cagtacctgg agattgaccc ataccaatac
    32341 atggaccaca agaattttct agtattctag ctccagcact tattatatct gccaaagccc
    32401 catttctagc aatcatctcc ataacttgtc ttgaacctgg tgctattacc aaactcacat
    32461 ccttatgtac tttatttcct ttcaggattt gtgctacttt cattaagtct tcataagaag
    32521 aatttgtaca acttcctatt gccacttggt ctattttaat cttgcctata ttttcaactt
    32581 catctacatt gtctgggcta tgaggttttg cagctaatgg ttttaattca tccaagttta
    32641 tagtaatctc ttcatcataa actgcatctg catctggttt tagctctatc catgcctctt
    32701 ctcttccttg actcttaaaa aattctagtg ttttttcatc acttgggaag attgaagtag
    32761 ttgctccaag ttcagccccc atatttgtta ttgtagctct ttgtggaaca gataggcttt
    32821 tgacaccttc tccaccatat tcataaactt tacctactcc accttttaca gtttgttttc
    32881 ttaacacttc taatattata tcttttgatg ataccatatt atttaatttt ccaactagat
    32941 tcaccttaca gacttttggt gcttttatat agtatgctcc tcctgccatg gctaaagcaa
    33001 catctaatcc accagctcca atagccatca tgcccacacc tccagcagta ggtgtgtggc
    33061 tatcagaacc taaaagtgta tctcctggtg ttgaaaatct ttctaaaaat acttgatgac
    33121 aaataccatt tcctggctta gagaaataaa ctccatattt atctgccact gtttgtatat
    33181 acttatggtc gtctgcattt tcaaatcctt gttgtaacat attatggtct acaaatgcca
    33241 cacttctttt agtctttact ttatctattc ccatagcttc tagttgaaga tatgtcattg
    33301 ttccagtaga atcttgtgtt aaagtttggt ctatttttat accaattgaa cttccagcaa
    33361 cagcttctcc atctactata tgttttttaa ttattttata aactatatta tctcccatat
    33421 tttcctccta aacaattata tcttaaatat atgaacctct aactgcttct tcttctgttg
    33481 tgcctttctc atgtgctagt atatcacaat ataattgaag aatttcttta tccattaaac
    33541 ttctttttaa tcttatagat gtagctctta tagcatttaa tagcttggta gcgttttctg
    33601 gagaaatata catttcatat tcactcaact tatttacaac tgcagctctt cctgaatgtt
    33661 tacctattac tatttttctt tcaagattta cttcacttgg gtcaaatggt tcatagttat
    33721 gtgggtcttt taaagctcca tctgcatgta taccagattc atgtataaac atattatccc
    33781 caactactgg tttccatgta ggaagtattc ttcctgatgc ctgtgctaca tactcacata
    33841 ttcctctaaa ttttctagta tctatattat ttaaatcaca tttataaaca cacttaagtg
    33901 ccattaaaac ttcttctaat gctgcatttc ctgctctttc acctaatcca tttactgtaa
    33961 caccaacata atttgctcct gctgctattc ctgcaagtgc atttgcagtt gccatcccaa
    34021 agtcattatg tgtatgcatt tctatatcaa aattagttct ttcataaaga gtttctattg
    34081 cattctttat agaaaaagga ttcataactc ctactgtatc acagtatcta aatctatctg
    34141 cccctgcttg ttttccaaca tttataaatt cagttaagaa gtctatatct gctcttgaag
    34201 catcttctcc atttactgaa acatataatc catttttctt tgcaaattca actgttttag
    34261 ccatattttc taaaacccag cctctagaag ttctcaattt attttctata tgaatgtcag
    34321 atactgatat tgatatagct actgcatcaa caccacaaga aatagattct tcaacatctt
    34381 ttattactgc tctattccaa gccattatat ctgattttaa atttctacta catatgtgct
    34441 ttattacatt tttttcatct ccacccatag taggtatacc aacttcaatt tggtcaacac
    34501 ctaggtcact taacatttca gcaatcatta ttttttctct atttgcaaat acaaccccag
    34561 ctgtttgctc tccatctctt aaagtagtat ctactatttt tatttccttt gctctatctt
    34621 ttgatataac gcacatatta atgcccccct tagtatactt ttaattttaa aacattaagt
    34681 cttatttttc attgatacct ctaacttatg attatttttt tattttttat tcattttaat
    34741 ttcatttgca atttattttt ttagcttttc atatcttgta atctattata ttactttgta
    34801 tcatttattg cactatattt tttctttttt gtgaaaactt cttaaaaatg aaagttatta
    34861 tgtttttctt gcattttaat ttaattttta aatagattta ttttcaaaaa acctttaaaa
    34921 ataaacctat aaaattccta ctaaaattta atttaagtta cattccattt taaagtatct
    34981 taatatattt ttaagctata taaataataa ttaaaaaatt tactaaaaat acttataaat
    35041 atgatattat taattggtta ataaaaaaga aaatttttca tgaaaggtaa gataacaatg
    35101 gatttcaaaa gcttagggat tagtgaaaat acaataaata ttctaaaaaa atcaggaata
    35161 acaacaccta cacctataca aaaagaaagt attaaactaa taaaagaagg aaaagatgta
    35221 atagcagaag ctcaaactgg aacaggaaaa acactagctt ttttacttcc gatatttgaa
    35281 aatatatcat tagatataaa tgatatacaa gtacttatac tttctcctac aagagaacta
    35341 gctattcaaa taacagaaga agctatgaaa cttaaagaat ctaaagatgt aagtattctt
    35401 gcagcatatg gaggaaaaga tattggttct caaataaaga aactaaaagg aaatattcat
    35461 atgattatag ctacaccagg taggctttta gaccatctaa atagaaaaac aatagacctt
    35521 agtaagttaa agacttttgt tttagatgaa gcagaccaaa tgttgcttat gggatttaaa
    35581 aatgaagtgg aagctatttt aaaagagact tcaaacaaaa agcaaacact atgcttttct
    35641 gcaactataa attctcaagt aaaaaaatta gcttatagat acacaaaaaa tcctgttgta
    35701 gtttctattc aaaaagaaga aatcactctt aataatataa aacaagaagt agtagaaact
    35761 acagatagaa aaaaattaga tgccttatgt aaggtactag atgaagataa tccttttatg
    35821 gcaataatat tttgtagaac taagagaagg gttgacaatc ttgaagaagc tcttgctata
    35881 agaggatata attgtcaaaa acttcatagt gatattgctc aatcaaaacg agaaagaata
    35941 atgaaatcat ttagaaattt agatatacaa tacttaatag ctacagatgt agcttctcgt
    36001 ggtcttgata tatctggagt aagtcatata tataattacg atttaccaga aacaccagaa
    36061 gactacatcc accgtattgg tagaactggt agagctggtg aagaaggcta tacatgtgct
    36121 tttattgacc ctaaaaatga acgaatgtta agtgaaatag agacggctat agaatctaaa
    36181 attagtagaa gaattataga attataattt atagattgct taaaatacca atgccacaca
    36241 aacactgtaa tatatagaaa gctacagaaa acatgtatca atctatactt tgctgttata
    36301 ctattttata ttaaagaaaa aagaggctat ccaaagtagg attagtctct tttattgtca
    36361 aaataatgaa aatatatttg acttcatata aaaaagagtg ccttataaac taaaagtcca
    36421 ttttgagaca ccctcttttt atcttttatt cttagtttta tattgcttgt ttatagttgt
    36481 ttaatattag attttgcaaa taatcttaat aaacatgcag atatattatc tatagtattc
    36541 ttatctatag tattctcttt agcaatattt tttgctacta catctaattt acattttcat
    36601 ttaattccgc tggccattta gcttctggat tttcctttgc aaacttctta ttcttataat
    36661 gtcctagtgt aaggaatgga attactatag tgaatagacc aagataacca caatatccat
    36721 atccatattt aacaatatta cttaatcctg taagtgatat aagcattgac actaccatta
    36781 ttgcacaagc tgtaaatacc cttcttttca ttcttgaaga aaggaaagaa agtgctttat
    36841 ggtcttcaaa tctatttaca agaccaaata tagtagttac tcctgtagac attaaacaaa
    36901 ggaataatgc aacattataa attatgtata tagtatgatt tccagattga cctgcaacat
    36961 aaagagtagg gagtgttgtt tgcccagcag caataatttc tctataccat cccattagca
    37021 tagttacagc aagtcctaat gcaattgcat tcataacaaa tgaaattatc attgccttag
    37081 tagcttcttt tgagttctta agaagtggtc ttgaacatcc tgcaagtgta ggtataacaa
    37141 ccgattgaaa acctgcataa ataaaagtat taagtattgg cttgatatag ccaggtgtga
    37201 aactcgttct atttgataat atttcagtta tttctggtac tttagctttt ataccaacaa
    37261 taaaaatagt aagagtacat actagaatag ctattgtcat tgctgtagct gctttagata
    37321 caagcatagc accaaatata gtaaagacaa gaagtacaac tccaataata aatacagcta
    37381 caaaataatt tactcctata ctttgaaata ctgctgctgc acctgctata acagcactta
    37441 cagctattaa aaccattaga tagtaatata tctcccatat tatttcaagt tttggatatg
    37501 gtctccaaag ctcacaaaat aaatccttat aattcctaca attgttatta ttatacatta
    37561 tgataacttc tctcatggta gcagtaagta taatcattgc taaaattgcc ataagtggtg
    37621 ctgtccatcc atactgcaca tagtactgag tttcttgatt ccctgtagca aatcctcctc
    37681 ctgcatgtga actaaaaaga acgcttgcaa caccaaaaat ggctaacata gagcccgtta
    37741 cttttgcttt ctttacactt ttttgcatga aatcatcctc cctaaaatga tattaaaagt
    37801 ttttatttta acactttatt gataaaacaa taacattttt gctcattaaa ttcaactata
    37861 tttttccaat gactttacat tttcaactta tttct
//
LOCUS       DAMJVG010000039        34740 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.039, whole genome shotgun sequence.
ACCESSION   DAMJVG010000039 DAMJVG010000000
VERSION     DAMJVG010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 34740)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34740)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34740
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.039"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(441..2828)
                     /gene="cadA"
                     /locus_tag="PC512_002035"
     CDS             complement(441..2828)
                     /gene="cadA"
                     /locus_tag="PC512_002035"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HDF2441777.1"
                     /translation="MEANNSIKKEFILGGLNCAHCAEEINNKVSKLQEVKSSNLNFIN
                     KKLTVNIKESFNEDTTIEKIIDIIDSTDPGLDIQISSKENAASKTSIKKELILGGLNC
                     AHCAEEINNKVSKLKEVESSNLNFVNKKLTVNISNNFEEDDVINKIKEIINSTEPGLD
                     IQVGSTDKVKGRTTEKSGAVNDTNKKELIPLIIGALVYIFGIYQTATGYESQFSNIVF
                     IVAYVIVGGDVLLRAIRNISKGRVFDENFLMALATVGALTIGELSEAVGVMLFYKVGE
                     YLQGVAVGKSRKSITSLMQIRPDYANLKVNSEVKVVSPEEVNVGDIIVVKPGEKVPLD
                     GVVVDGVSMLDTSALTGESVLREVEKGDEILSGVINKNALLSIEVTKSFGESTVSKIL
                     DLVENSSIKKSKTENFISKFSRYYTPIVVIAALLIAFVPPLVISGEVFSDWLYRGLIF
                     LVVSCPCALVLSIPLSFFSGIGFASKNGILIKGSNYLEALRSVDTVVFDKTGTLTKGV
                     FNVTKLNPEGISEEELLEYAAIAEVNSNHPIAKSILSYYNKKIDLDTIDSYEEIAAYG
                     IRVKHNGNFILAGNEKLMKKENISYSSAKEVGTVVYIAVDKVYRGYIVISDEVKEDSK
                     NAIRSLKEIGVKEVVMLTGDNEKVAKNIAQELELDTVYSNLLPNEKVDRLEDLYEGRT
                     EKEKIAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVLMTDEPSKISKAIEIA
                     NKTNKIVWQNIIFALGVKIIVMILGAGGVATMWEAIFADVGVALIAVVNAMRAMR"
     gene            complement(2851..3216)
                     /locus_tag="PC512_002036"
     CDS             complement(2851..3216)
                     /locus_tag="PC512_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2441778.1"
                     /translation="MREEINDCNCNIVHEEIVTEAKSTMPDEEMLYDLAELFKVFGDT
                     TRVKILYALFANEMCVCDIASLLNMTHSAISHQLRVLKQARLVKFRREGKTVYYSLDD
                     SHISQIFDCGLNHIRETYK"
     gene            3415..4263
                     /locus_tag="PC512_002037"
     CDS             3415..4263
                     /locus_tag="PC512_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441779.1"
                     /translation="MSNKKKKDLDTSYMPYLDPANYADYITNEEIPQDELRNDPQISN
                     GYTKIPNNQNINNLYPNNVNHYPKSSNSPNNLPNTNNTSGNMNYNTSATNNMPNNMNN
                     NTGMPNNMSNNMNSNMGMPNNMPNNMNSNMGMPNNMPNNMNSNMGMPNNVPNNMNSNM
                     GMPNNMSNNMNSNMGMPNNMSGNMNNNMYGNTGMPNNMNSNMGYNMNNTMGIPNFSCN
                     QNMPPNVLMMIPGVICHNTMQGMPVVMPSTMPPNIYPTPYGSSNMSVQGIPQATNIEE
                     FDEEEM"
     gene            complement(4700..5788)
                     /locus_tag="PC512_002038"
     CDS             complement(4700..5788)
                     /locus_tag="PC512_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441780.1"
                     /translation="MNFNFAKATNSRLMGSLGLIINWIDDENNHFCQYFLLDAEGLGL
                     ADYVSLNNPTQEEAYMEEERLMGGFGSDRVELTKDESLFLVSYFGNKNLYYDKLLPGD
                     KCEYIDIIKNYKTDLTIEKLYNKICKRVDEEVEFINYMTMRFIAWDRESLKYFSGSDE
                     IANMHITNINGTLLKNVVSDKGQGRYISEALYEDNDGYYICKIAFCISKCYETGFRIN
                     SLLVTDKEPMYDFEVFDEISKSEFVSVYSVNSPEEFAGVFYRENPFLLKSNMNEGIFF
                     TRFNFNNDHVKENVYIINNDMKAIYYLMGNKFFIGTYNENDCNYINEISQSNYSDYIK
                     FEEKFFFEQNALYDFAESGSLDFDDFLE"
     gene            5913..6641
                     /locus_tag="PC512_002039"
     CDS             5913..6641
                     /locus_tag="PC512_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family hydrolase"
                     /protein_id="HDF2441781.1"
                     /translation="MKNIAAFFDIDGTLYRDSLMVEHFKKLIKYDIIDQKNWYKHARD
                     TFMDWDKRQGNYDDYLLEICDLYVDSLKGLDKTCINFTSDQVIKLKADRVYKYTRSRI
                     EWHLNQGHIVIFISGSPGFLVEKMAKKYNVTDFLGSDYVFENNIFTGTVIPMWDSISK
                     NNAINDFVVKYDLDLSNSYAYGDTNGDINMLKRVGNPIAINPTKELLSQISLDEEISK
                     NVEIIVERKDIIYSLSTDVNIVDI"
     gene            complement(6843..7334)
                     /locus_tag="PC512_002040"
     CDS             complement(6843..7334)
                     /locus_tag="PC512_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441782.1"
                     /translation="MSIKVAYGGVLLALNVILLTLTNIIPVNTLFIMGLASLLVSIVI
                     MEWGFKSGIAFYIGSIVLGFIVMASKSQWIVYSLTFGIYGIVKYLIEKDRSIYIEYFM
                     KLVFANIMILILYFLLRTIVYIPINIFIIGSFEIAFIVYDYVYSSFIGYYNNRLRKML
                     FKK"
     gene            complement(7345..7788)
                     /locus_tag="PC512_002041"
     CDS             complement(7345..7788)
                     /locus_tag="PC512_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441783.1"
                     /translation="MYSNTYNNENFMRARSFIENSEFKKAYDFLKTLTDKCAEWYYLT
                     GFSAMNIGYYEEGEDFLKRAKFMEPENSEYSDALRSYTQYRNDYSNRADNYNRRRRND
                     LDGCCCCCCDDCCCCLGDDCCENCAKLWCLDSCCECFGGDLITCC"
     gene            complement(7778..8617)
                     /locus_tag="PC512_002042"
     CDS             complement(7778..8617)
                     /locus_tag="PC512_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441784.1"
                     /translation="MFGYVKINKMDLTFREYDYYKAYYCGLCKYLKRNHGEISRFSLN
                     YDITFLIVLLTAVYNPESISTEEVCIVNPFKKKKVITNDITEYAASMNILLTYYKLED
                     NLMDDKRIKDKLAYYIYKNKLKLAYEKYPEKAEYIKQQLNELNKLEKDKNINIDEVSS
                     IFGNIMGEVFVYKKDENERNLRMIGFNIGKYIYLLDAYEDLDEDFKKGRYNPFIEYID
                     KNDELKEKVKKIIVTSLGFLARGIDNLNLNKNVGIIENIIYSGVYLRYINILESRGGK
                     NVQ"
     gene            complement(8836..10221)
                     /locus_tag="PC512_002043"
     CDS             complement(8836..10221)
                     /locus_tag="PC512_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2441785.1"
                     /translation="MDNLNKKFLMEYIDEIQGELRDISDKIWKNPELQYKEYYASNLQ
                     KECLKKHGFSIEGLEGMDTAFVASYGEGRPVIAVLGEYDALDGLSQKVSTTKEPIVDG
                     GAGHGCGHNLLGTGSIGAVIAVKELIKLKKLKGTIKYYGCPAEEDLSGKVLMIKKGFF
                     DGIDCAFSWHPFDINTPIRIPTLANYSVKFRYNGISAHAAQAPYNGRSALDAVELMNI
                     GCNYLREHIFDNCRVHYVTTNGGKMPNIVPDFAEVWYYIRGVKMEHVRDVFGRIVDIA
                     KGAALMTGTIMEYDIISGVYDYIPNTILTDILSQNMKLVGVQNYNEDDYYFADKLAET
                     VSIDKRSSVSSVLSGNKDITKMNLHDEVTDDTFTHNNCISLSLDIGDVSYIIPTAQCS
                     CSVWPIGISAHTWQSCASAGSDMGFKAMLLASKSISCSINDVMLDELVINKAKKELKD
                     TVGSFKYIPII"
     gene            complement(10394..11137)
                     /locus_tag="PC512_002044"
     CDS             complement(10394..11137)
                     /locus_tag="PC512_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HDF2441786.1"
                     /translation="MKKVLIVGESWVKNITHIKGFDTFVTTHYEEAVKWLKEAIESGG
                     YETVHMPAHVAADSFPYKLEELNEYDCIILSDIGSNTFLLSNSTFIDCNSNPDRLELI
                     KEYVNNGGALIMVGGYMSFTGIDAKARFGETAIKDVLPITMIDKDDRVEKPAGIIPEV
                     IDSEHPVLKGIPTEWPKFLGYNKTVARDNCPVLATIGGDPFVAVGEFGKGKSAIFSSD
                     CAPHWGPKEFTDWKYYNKLWVNMLDWLTC"
     gene            complement(11157..12419)
                     /locus_tag="PC512_002045"
     CDS             complement(11157..12419)
                     /locus_tag="PC512_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDF2441787.1"
                     /translation="MKKILLDTLNSKKQEYIDYLKELVSIKTEDVGHGILGGFEKEGQ
                     EYIEKLANYIGFSVDRQEMSEELIKKAKNIYKEGNLGHNYQDRYNLICKYSDDLPGKT
                     IVFNGHVDTMPPGDISKWKYNPYRATEDNGKLYGLGTADMKSGLIASILAVKLIKDSG
                     LNVPGNVKIMSVVDEEGGGNGTINAVMNGIDGDCCIICEPSEQNLIVAHMGFVFFEVE
                     VKGVSLHCGSKWEGVNAIEKAMLLLQDIKELEHNWLMIYKHPLLPSPTINLGVINGGT
                     AGSTVPDKCVFNLCVHFLPNIMSYEQVVNDVTNVIMTRANGDLWLKDNKPNINIYQSG
                     LGFEMDKDSDFVVNAHKILEETLGKKLEIKGSTAGNDARVMKNLAEIPTLILGPGSIE
                     QCHSIDEYVEIKEYLDSILMYASLILNL"
     gene            complement(12603..13601)
                     /locus_tag="PC512_002046"
     CDS             complement(12603..13601)
                     /locus_tag="PC512_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter permease"
                     /protein_id="HDF2441788.1"
                     /translation="MSSITKHKEEKSSPLLTKLTSVFRDQGSAAVGLVIIFIIMSVAS
                     SNFLTLDNLINVGRQISINAILAVGMTFVIITGGIDLSVGAVIALVGTFWATTVVNYN
                     APIWVGMILALAIGTILGVIKGAIISTQKLPPFIVTLAMLTIISGASFVFTGGRPISV
                     NTDAFKMLGRGYIGPIPIPVIIMIIVVIAGHFLLKRTNFGRHVHAVGGNEEAARLCGV
                     KVNKVIVKVYALAGLLTALAGIILSSRLASGSPTVGDGAELDAIAAVVLGGTNMMGGS
                     GSIVGTCIGVGIIGILGNGLNLLSVSSYNQMIIKGLVMLFAIWINNIKLKKSAKSK"
     gene            complement(13585..15096)
                     /locus_tag="PC512_002047"
     CDS             complement(13585..15096)
                     /locus_tag="PC512_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HDF2441789.1"
                     /translation="MSNIILKLSNIAKEFPGVRALDNVNFELFHGEVHALLGENGAGK
                     STMIKILTGAHSKTSGKFIFEGKEIENISPDISKKIGINAIYQELTVFDELTVAQNIF
                     MGKEINGKVLTNDKKMNEEAKKIFDNMGIDINPNSLVKELSIAQKQMVEIARVLSSET
                     KVLIMDEPTSSISKKETEILFRLINDLKESGVSIIYISHRMEELFEICDRITIMRDGK
                     TISTLNTKDVSSEEELVNLMIDRKLDQFFPKRKVEIKEEIMRVENLTKNNVFNDISFN
                     IRKGEILGIGGLVGSKRSEIVEAIFGLRTYDSGKIYLNNEEVKFKTPSDAIENGLGLI
                     TEDRKGTGLFLQMSVKENTTMAGLKKISKFKSIIDRKKEKEILEKYIEALKIKTPHMN
                     QVIQSLSGGNQQKAIIARWLLLQPDILIMDEPTRGIDVNAKAEIYNLMGDLVESGVSI
                     IMISSEIPELISMSDRIMVMREGHISGFLEGEEMVENNVLKLAFGGKINEFNN"
     gene            complement(15150..16112)
                     /locus_tag="PC512_002048"
     CDS             complement(15150..16112)
                     /locus_tag="PC512_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HDF2441790.1"
                     /translation="MRVRKILSLGIAGILAIGMLTGCSMEGPSKSDNKGGSDKKDLTI
                     GVSTITLQHQFFIDIDEGIKEKAKELGVKVIVNDPDQDVAKQTSAIEDFIQQNVDGMI
                     VLGTDNSAIVPAVEGAFEKMPVVTVDAVLNTENITSYVGTVSYDAGKKLGEYTKKYID
                     EKLGGKSEIAIVTDLKSQIQMQRIDGFKDALKGSANVKILNSQPGYDREESLNTVENL
                     IQSNPDVDIIYATAENSVLGAKAALESAKNKDVKIVGFDLTEEASSGITDGTILAMIQ
                     QQPKEMGRLAVEAVVKAIKGEKVEKNIPVPALLYDKENIKDFKN"
     gene            complement(16160..17050)
                     /gene="rbsK"
                     /locus_tag="PC512_002049"
     CDS             complement(16160..17050)
                     /gene="rbsK"
                     /locus_tag="PC512_002049"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HDF2441791.1"
                     /translation="MGNIVVIGSVNMDMVCSVDKRPEKGETVLGNSFFTSPGGKGANQ
                     AISASKLGANVKMISCIGEDGLGEELIRNFRTNKVDYSLVSRNNHKSSGVAVITLCEN
                     DNSIVVVPGTNELVDIELIKKNEEEIKNADIVLLQLEIPLKTINYVVNFCFENRIRVL
                     LNPAPAVKLNEDIIEKVTYLTPNEHEYKIVFDTNEGIEEVLKKYPNKLVITEGKNGAR
                     FYDGEEIKHVSCISVDVQDTTGAGDTFNGALAVAITEGKNLYTAVEYAVVVSGLSVTK
                     LGAQSGMPYKEDVEKYLNNK"
     gene            complement(17092..18105)
                     /locus_tag="PC512_002050"
     CDS             complement(17092..18105)
                     /locus_tag="PC512_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDF2441792.1"
                     /translation="MSITIKEIGELAGVSKTTVSKVINNKDENISQATREKILKIMKE
                     KNYVPNKLAQSLVTKKTNTIGLLIPDIRNPFFTDVSRGVEDKANEEGYNIILCNTDED
                     AKKEYEGIRTLSERMIDGIIFAASSNTNWKEANYKDIKIPTVLIDKKISMNKETLKGI
                     VKINNFEGAYIATKHLLDIGNKKIIYLSGPLQNEIAVDRLEGYKKALIECNLSYNPAY
                     VFEGKYKIEWGQEFIKNLEKIDFDAIFCANDLIAIGVIRGLKERGLSIPNDISVVGFD
                     DIQTSSLISPSLTTVKQPSYDIGYKASEILINCLRGDKKESFDELIFKPELVIRDSTK
                     ESE"
     gene            complement(18333..19310)
                     /gene="bioB"
                     /locus_tag="PC512_002051"
     CDS             complement(18333..19310)
                     /gene="bioB"
                     /locus_tag="PC512_002051"
                     /EC_number="2.8.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin synthase BioB"
                     /protein_id="HDF2441793.1"
                     /translation="MEKYIIKLKNKVLREKEISYEEALNLISLDTNNKNDFDILLKSA
                     NEIREYFMGRKADLCTIMNAKSGKCSEDCKFCAQSSYYKTGVEEYSLLDYNEILNRAK
                     EMESKGVHRFSLVTSGKGMSGKEFNNILNIYEGLRENTNLKLCASLGIIDYEQAKMLK
                     SAGVTTYHHNVETCRDNFHNICTTHTYKDRIKTIKDAKKAGLDVCVGGIIGMNESEEQ
                     RLKMAFEIRELNVKSFPINILNPIKNTPMENYDVLEPMEILKTTAVFRFIIPNVYIRY
                     AGGRLSLKGYDKVGFNGGVNSAIVGDYLTTVGSGIENDKKMIIEQGFEL"
     gene            complement(19516..19779)
                     /locus_tag="PC512_002052"
     CDS             complement(19516..19779)
                     /locus_tag="PC512_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441794.1"
                     /translation="MKIYYEKENSKKANVNNIPSVFAFNFLRNFLTSKEYEETRKEYF
                     INNLTKSQVNQAMKDLKWLFREYEGLEVITMESLDGVKTRIVL"
     gene            complement(19849..20922)
                     /locus_tag="PC512_002053"
     CDS             complement(19849..20922)
                     /locus_tag="PC512_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HDF2441795.1"
                     /translation="MEKSKVYFCDLYSNSQNKNVPNNVRRLFDEAGFKDLIEKNDQVA
                     IKLHFGEKGNTTYMSPVAVRQVVDKVKDCEGKPFLTDTNTLYTGSRTNSVDHLTTAIE
                     NGFAYAVVNAPVIIADGLYSRNYENVKIDKKHFESVKIGGEIYNSSAMIVMSHFKGHE
                     AAGFGGALKNLAMGCASAAGKQMQHSDVTPVVKEKKCVGCGKCVNSCPTKAISIVDKK
                     AVIDSDVCYGCGECPTVCPTRAVTIQWESDSDVFVEKMAEYAYGAVSNKKDKVGYITF
                     VMNVTPLCDCVPWSGRPIAHDIGILASTDPVAIEQACYDLICKEMGHDVFKHEHPHVN
                     GTRIIDYACEMGMGSKEYELIKL"
     gene            complement(21181..21939)
                     /locus_tag="PC512_002054"
     CDS             complement(21181..21939)
                     /locus_tag="PC512_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2441796.1"
                     /translation="MREYIAFTKKEFKENLRNYKLFSLIILFLIFGISSPISAKFMPD
                     LIAHFAPTLKVTAAPTALDSWTQFFSNISGLGMSLTLIIFCNILSNEYSKGTLVIMLT
                     KGLSRSSIVLSKFSVTVIIMTIGFWLSFLFAYGYTMYFWPTANLNHIIFSAFNLWLIG
                     IMYISVLILGCVLFRPAFASVLLVLVATLLLSLISIPKQIAPYTPNFLMSKNIDLISG
                     KVAMPEFIIPIIITVLISIVCLLAAVILFNKKPV"
     gene            complement(21936..22853)
                     /locus_tag="PC512_002055"
     CDS             complement(21936..22853)
                     /locus_tag="PC512_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2441797.1"
                     /translation="MNIVSINGLSKGFGNRKIIDNLNFTVPEGSVFGFVGKNGAGKTT
                     TMKMVLGLLKPDSGTIDVCGEKVTYGKTSSNRHVGYLPDVPEFYNYMRPLEYLSLCGE
                     ITGLSKKEIQIRSEELLSLVGLRNEKRRIGGFSRGMKQRLGIAQALLSRPKLLICDEP
                     TSALDPVGRKEILDIMLKIKDSTTVIFSTHILSDVERICDHVAILNKGSIALSGTLSE
                     IKSMHGKDRLLLEFASNDEIQKFKSSDGIKSLLKDSEETNMEIVLHGKDIKAIQKTVI
                     STLAEMNLCPVKMELIELSLENLFLEVVK"
     gene            complement(22853..23053)
                     /locus_tag="PC512_002056"
     CDS             complement(22853..23053)
                     /locus_tag="PC512_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLDc_N domain-containing protein"
                     /protein_id="HDF2441798.1"
                     /translation="MENLMEYLPLLVPVIILDLILIITALVHVLRHPNYKIGNKAIWI
                     IVVLFISLIGPILYFTIGRGEE"
     gene            complement(23058..24152)
                     /locus_tag="PC512_002057"
     CDS             complement(23058..24152)
                     /locus_tag="PC512_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2441799.1"
                     /translation="MNELNIAKTLILKRKEKGITQDELANYIGVSKASVSKWETGQSY
                     PDITFLPQLATYFNITVDELICYEPQMMKEDINKLYNKLCKDFTVKPFDEVMDEIREI
                     IKKYYSCFPLIFRMGLLIVNHYDIVDEKKRELLISEALEIFIRIQETCNDIDICRQAK
                     SMEATCYILLNQPIQVIDLLQNSNFPMINESILLAQGQMMNGQMDEARETFQLGAYQN
                     LISLVQNLVGILQNADKLQMKEIERRILAISDIFELDTLSPAIMLSSYLTQAQINLIH
                     GDNEGAIKSLRKYVDLATRDIYPIIIHGDDFFNKLDRWISEIGTGITRDDTIVKAGIV
                     AAIKNNPMFSVLSENKEYKFLIEKLSLLEE"
     gene            complement(24662..24802)
                     /locus_tag="PC512_002058"
     CDS             complement(24662..24802)
                     /locus_tag="PC512_002058"
                     /inference="COORDINATES: protein motif:HMM:NF021468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2185 domain-containing protein"
                     /protein_id="HDF2441800.1"
                     /translation="MNGEGCILSNKITKECYKVGYMIREKSIDIYPDSGWGFMTWDEN
                     GE"
     gene            complement(25112..26419)
                     /locus_tag="PC512_002059"
     CDS             complement(25112..26419)
                     /locus_tag="PC512_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDF2441801.1"
                     /translation="MDISRSVDNSLNRTIEFLKELIKIDSQQGEPISQCPFGIGPKKS
                     LDKTLDYCASLGFSVKNIDNYIGYAEIGEGEELIGIPMHLDIVPPGEGWSVDPFSGAV
                     IDNIIYGRGVIDNKGAVSMLIHVLKNIEDMYPTINKRIRLIFGTNEETGMKCIKYYLD
                     KGEEIPSMGFTPDAMYPVVNGEKGRVHIRIEKEIKIDKSKPYIIVSGGTKENVVPSHC
                     TAKIINGIISELTTKGVAVHASNPEKGENAISKMVIKIVEDNMDFQHREDIELVSKYL
                     CSDYYGDALGINQYDEVFKNTTLNLGILKVNEEKIVCELDIRYGKNIVLNNIIDRFKK
                     VFCNGWKIEVIVHKDLHYVDESNLVLKKLLEAYEEVTDENGYTIAMGGGTYASWFKDM
                     VAFGPKFLAYKTGGHGVDERVPINHIRKNMEIYTLALIKLLEL"
     gene            complement(26484..26963)
                     /locus_tag="PC512_002060"
     CDS             complement(26484..26963)
                     /locus_tag="PC512_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-2-amino-thiazoline-4-carboxylic acid
                     hydrolase"
                     /protein_id="HDF2441802.1"
                     /translation="MSEKMYTEKEYLEGIRGATGERAVWFYLLMKEAEKLGANPDDIC
                     KEAIYGFGKMRGQKYNVADTPGKMAEMLYNSKGQKVFEMELVENTDENGVLKFHHCPL
                     DAAWKEYGLTKEERKEICRLACYGDYGRVDCAQGVKLDFAQKCAHDDEVCELVFTKK"
     gene            complement(27010..27873)
                     /locus_tag="PC512_002061"
     CDS             complement(27010..27873)
                     /locus_tag="PC512_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDF2441803.1"
                     /translation="MQEIKNKEVKNGQGPTEVNKTRVLTKKDVTKTYLRWWWTAELSN
                     SFERMQALAVCASFTPALEKLYKRKEDLVDALKRHLQFFNTQAIWGGLIHGTVLAMEE
                     EKATEGKIPGEVISGVKNGLMGPLAGIGDTLDFGTFQTIFLALGASFGAEGSVIGAFF
                     PIMFSILLFCEGYYLFHLGYSLGRDSIKKILSGGIVNKIIDGASILGMFMMGALSATT
                     VKLSTPLSFDIGGKAIVVQDTLNMIAPGLLPLGVVFFVYWGMKYKKWTITKLLVILVV
                     LALVGSFIGIF"
     gene            complement(27873..28628)
                     /locus_tag="PC512_002062"
     CDS             complement(27873..28628)
                     /locus_tag="PC512_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2441804.1"
                     /translation="MESVLMLAIVTGLWYWFAAGLAGYTLFSTLKSPLFIGFSLGLLW
                     GDVTTGMIVGASIEMVYLGMVAAGGNIPSDKCLAALIAIPVALQTGVNAEVAVSIAVP
                     LGVIGVLVNNLRRTGNAVLVHKADKYAEEGNTKGIWRCATLYSLIFGFVLRFPIVFVC
                     NFFGADLVQSLLDVIPQWLMNGLTVMGGILPALGFATTIFTIGKNKFLPMFIIGFFMV
                     QYFEISITAAAIFGVCIALLITFMKEDKRVGEV"
     gene            complement(28655..29143)
                     /locus_tag="PC512_002063"
     CDS             complement(28655..29143)
                     /locus_tag="PC512_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2441805.1"
                     /translation="MAKITLVRVDHRLIHGQVITKWVKIAQAQKIIIVDDFLGQDEFM
                     ADIYKMAAPSGVEVVILTAEDAGQAFQNNTLGDKNIFILFKNVDMANKAYKAGLKYEK
                     IQLGGIPNEAGKKMVFTAVSLGNEDVEQLNELNENGVEIVLQVIPEESSMTYENALKK
                     FK"
     gene            complement(29161..29562)
                     /locus_tag="PC512_002064"
     CDS             complement(29161..29562)
                     /locus_tag="PC512_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIC"
                     /protein_id="HDF2441806.1"
                     /translation="MNKYKVIILCHGTWGKVLVEETNKNFGLSNQYEVLSLSSEKDVS
                     VFMKEVEEVVDKEDVKIIISDLYGGSTSSVAIAVAIRRGIDAINGLSLQTILIVDEEL
                     SKEDKLHTLPERIVKKNNNLCVDLIKEFKKI"
     gene            complement(29565..30062)
                     /locus_tag="PC512_002065"
     CDS             complement(29565..30062)
                     /locus_tag="PC512_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2441807.1"
                     /translation="MSLVKYCRCDDRLIHGQVIYKWVKHLGVKKIVVVDDETTNDVIA
                     KGLIKMAAPKNIDLSILTVSESRRYFYNNQADDNVFVLIKNLDTANRMIEEGINIKKL
                     IVGRIPTGIGKKKISQNVYINKKEFLLIDEFIKKNINVSIQMVPDEEEVELNQNINRY
                     KGEFI"
     gene            complement(30086..30490)
                     /locus_tag="PC512_002066"
     CDS             complement(30086..30490)
                     /locus_tag="PC512_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2441808.1"
                     /translation="MIGIIVMTHGSFSEEIIKSCELIAGPAERTAAIKLNRNDNIEDL
                     NKNFVEKLNELDEGDGVLVLADLLGGSPSNVASLNLKKGGKFHALTGVNLPMLLEALI
                     NREGKSLEELAEACIEAGQTGINNINKVLSSM"
     gene            complement(30720..33287)
                     /locus_tag="PC512_002067"
     CDS             complement(30720..33287)
                     /locus_tag="PC512_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2441809.1"
                     /translation="MTQKKLSRKEKVLICLKRLTEEHLNFNNGIRFGFDAEYIATEVG
                     INRSNASKELNQLIKESIIIKIKGKPVQYLYKESIESILGKKLNKGIFDNINSINEYS
                     ENDSIKDEYILESIKKENNIFNLVGCDGSLRSQIEQAKAAVIYPPKGLSTLIIGPTGV
                     GKSIFAEYMYKYSLTIKEDSDNAPFIIFNCADYSDNQQLLLAQLFGYVKGAFTGADKD
                     KYGIVHEANNGVLFLDEVHRLSAEGQEMLFLLMDKGIYRRLGEANKVHECRVMIIAAT
                     TEDPETAMLETFLRRIPVTIKIPSLEERGFQERMKLICYFFKEESVRIGVKLKVSKEV
                     IKAFILYKCKGNIGQLKSDIQLICARAFLDYMTYKRECVYVRLSLLPNNIRESLYGNN
                     RKEEFVQNFSFIGKDDIIFLPEEKDFESENLLIENKKYDLDFYGMIKETWNKLQQEGI
                     KESQIRSVIDGDIQKYSYNLMNTFIYNSSNQTAYNNIVNDSIATTVKYILQKHDKWSK
                     REGLDKLIKAIALHIQNLIERIKIGNIVKHPNKDEIMKERAYEYNIAKEILSNMSLMY
                     GVEFPEDEAIFLATFLYLSYVGLNEESIAILVIMHGESTASSMVNVANTLLDCNHAVA
                     INMGLEDRVQDILVQAVEIANKIDKGKGILILTDMGSILTFAKVIRDATGKEVKAIDM
                     VSTPIVIEATRKALTPEMTLEKLYFNIIESIKKHYGDMEVTYAEKDNGGRYFDRLLID
                     NISKTLTFLNGEKAYFILKEVINRISEHYSLVIQDELLVKFIFHCSCMIERVIIKESL
                     VYKSYEERISRNKELYLVIKESFKLVEETFDIIISDMEYANILDIFESQYDTDKFKS"
     gene            33453..34196
                     /locus_tag="PC512_002068"
     CDS             33453..34196
                     /locus_tag="PC512_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase"
                     /protein_id="HDF2441810.1"
                     /translation="MNFLSDLHTHSIVSGHGYSTLLENINYCKENGIKILGTSEHGPK
                     MPGSPHRWYFHNIQNIPRIINNIIILRGCEANILDIKGNIDLEPFVIPRLDYLILSFH
                     EAVFSPNTLENNTKALINAINKHDNIEILGHLGNPNYPIDYELIIKLAIEKNILIEIN
                     NCSIKGVSRNGSSDNCKYIATLCKKYGAKIILTSDAHICFDIGNYEYSENILKEINFP
                     DELIMNYPKKLINHFHQKGKLLDVDYTNI"
BASE COUNT        11262 a         6360 c         3560 g        13558 t
ORIGIN      
        1 cttaaaaata attcgtcaat actttttaaa attatttttt aaaaatattt actttcttat
       61 attacataat ttattgaatg gcagtcatac tgttggttta gagtatttta acacacacat
      121 tttgttgtaa aaattacaac tattaatata atatatatac aatcataagt attataattt
      181 ttatgaatct aatttaaact taatataaac ttattaataa accttctatg tctaaatttt
      241 aaaattacaa tataaaagct ctacactaaa taaatacatt aaataaacat aatggataat
      301 gaatataaat ttatatatgc aaagcgctcc aataaaaagg taccaataaa gttaaaagaa
      361 acttattgat acctttcatt attacatact tcaatatata attataagtt ttttaaatag
      421 tatggattta catttatccc ttatctcata gctctcatag catttactac tgctataagt
      481 gccacaccta catcagcaaa tatagcttcc cacatagtag ctactcctcc agcacctagt
      541 atcataacta taatttttac tcctagagca aatattatgt tttgccacac tatcttatta
      601 gtcttgtttg ctatttcaat tgctttagat atcttgctag gctcatctgt cataagcact
      661 acatctgcag cttcaatagc agcatctgaa cctaagcctc ccatagctat accaacatca
      721 gcacgagcta atactggagc atcatttatt ccatcaccta caaacgctat tttctctttt
      781 tcagttcttc cttcatataa atcttctaat ctatctacct tttcattagg aagtaaattt
      841 gagtaaactg tatccaattc taattcttga gcaatatttt ttgctacttt ctcattatct
      901 ccagttaaca ttacaacttc ttttacccct atttctttta agcttcttat ggcattttta
      961 ctatcttctt ttacttcatc agagataact atataacctc tatatacttt atcaacagca
     1021 atatagacta ctgtgcctac ttctttagct gatgaataag atatattttc ttttttcata
     1081 agtttctcat tacctgctaa tataaaattg ccattatgct ttactctaat tccataagct
     1141 gctatttcct cataactgtc tattgtatct aaatcaattt ttttattata gtaacttaat
     1201 atggactttg ctattggatg atttgaattt acctccgcaa tagctgcata ttctaataat
     1261 tcttcttctg atataccttc aggatttaac ttagttacat tgaacacacc tttagtaagt
     1321 gttcctgttt tatcaaatac tactgtatct acacttctta aagcttctaa atagttactt
     1381 cctttaataa ggataccatt tttagatgca aacccaattc cactaaaaaa actaagtggt
     1441 attgataaaa ctaatgcaca agggcaagaa acgactaaga atatcaatcc tctatataac
     1501 caatcactaa atacctcacc tgagattaca agtggtggca caaatgctat taataaagca
     1561 gctattacta ctattggagt atagtatctt gaaaacttag atataaagtt ttctgtcttt
     1621 gattttttaa tgctagaatt ttcaacaagg tcaagaatct tagaaactgt tgattctcca
     1681 aaactctttg taacttcaat actcaataaa gcatttttat ttataacacc tgataagatt
     1741 tcatctcctt tttcaacttc tctcagcact gactctcctg tgagtgcaga agtatctaac
     1801 atagaaactc catctactac tacaccatct aatggtactt tttcaccagg ttttactact
     1861 attatatcac ctacatttac ctcttctggt gacaccacct taacttcaga attaactttt
     1921 agatttgcat agtctggtct tatttgcata agtgaagtta tagactttct ggatttacca
     1981 actgcaacac cttgtaaata ctctcctact ttatagaaaa gcataacccc tactgcttct
     2041 gataactccc ctattgttaa tgctcctact gttgctagag ccatcaaaaa gttctcatca
     2101 aatactcttc cttttgatat atttcttatt gctcttaaaa gcacatcacc acctactatt
     2161 acataggcaa ctataaatac tatattgcta aactgacttt cataacctgt agctgtttga
     2221 tatataccaa atatatatac aagtgctcca attataagtg gaattaattc tttcttattt
     2281 gtatcattta cagctcctga tttttcagta gttctccctt ttactttgtc agtagaccct
     2341 acttgtatat caagccctgg ctctgttgaa tttattattt cttttatttt atttataaca
     2401 tcatcctctt caaagttatt acttatattt actgtaagtt ttttatttac aaagtttaaa
     2461 ttagaagatt caacttcttt taatttagaa actttgttat taatctcttc tgcacaatga
     2521 gcacagttta atcctcctaa tataagctct tttttaattg atgttttact agctgcattt
     2581 tctttagaac ttatttgtat atcaagacct ggatctgttg aatctattat atctattatc
     2641 ttttctatag tagtatcctc attaaaactt tcctttatat ttactgtaag ttttttattt
     2701 ataaaattta aattggaaga tttaacttct tgtagtttag aaactttatt attaatctcc
     2761 tctgcacagt gagcacaatt taatcctcct agtataaatt cttttttaat tgaattattt
     2821 gcttccatat atattcactc ctctcattta tcatttataa gtctctctaa tatgatttaa
     2881 tccacaatca aatatctgac ttatatgact atcatctaat gagtaataca ctgtttttcc
     2941 ttctcttcta aactttacta atctagcctg ctttaatact ctaagttgat gagatattgc
     3001 agaatgagtc atatttaata aactcgctat atcacataca cacatttcat ttgcaaataa
     3061 tgcatataat atctttactc tagtagtatc cccaaatact ttaaataatt ctgctaaatc
     3121 atataacatt tcttcatctg gcatagttga tttagcctct gttactattt cttcatgtac
     3181 tatattacaa ttacaatcat ttatctcttc tctcattttt aatcctccat tattttaata
     3241 tatgaataac tgttcatatg ttcattatat gttatcattt ctaaatttgc aacaataatt
     3301 tttattaatt taatataaat agaatgcaca tattataaac ttttttaata tatatattat
     3361 tagaataagt ttttgtaaac ttttttatag ttttctagga ggtgcaagtt taatatgagt
     3421 aacaagaaaa aaaaggattt agatactagt tacatgcctt acttagaccc agcgaactat
     3481 gcagattata ttactaatga agaaattccc caagatgaat tgagaaatga ccctcaaatt
     3541 tctaatggtt atacaaaaat acctaataac cagaacataa ataacctata tcctaataat
     3601 gtaaatcatt atcctaaaag tagtaattct ccaaacaact tgcctaacac aaataataca
     3661 tccggaaata tgaattacaa tacatctgct acaaataata tgcctaataa catgaataat
     3721 aatacgggta tgcctaataa tatgtctaac aatatgaata gtaatatggg tatgcctaac
     3781 aatatgccta ataacatgaa tagtaatatg ggtatgccta acaatatgcc taataatatg
     3841 aatagtaaca tgggcatgcc taacaatgtg cctaataaca tgaatagtaa tatgggtatg
     3901 cctaacaata tgtctaataa tatgaatagt aatatgggca tgcctaacaa tatgtctggc
     3961 aatatgaata acaatatgta tggtaataca ggtatgccta ataacatgaa cagtaatatg
     4021 gggtataata tgaacaatac tatgggtatt cctaacttct catgtaatca aaatatgcct
     4081 cctaatgtac ttatgatgat accaggagtt atatgtcata atacaatgca aggtatgcct
     4141 gtagttatgc ctagtactat gcctcctaat atatatccta ctccttatgg ttctagtaat
     4201 atgtctgtac aaggtatacc acaagctact aatattgagg aatttgatga ggaagaaatg
     4261 taatatatat ttttttaagt aagttgtata aaacattaat aattgaccat aataataaat
     4321 gtattcctca taatattccc ccaatattat tataggtata gaaagttgac tgaatatgcg
     4381 cttattcggt caacagatat taacataatc taataagata aacatagaaa aagtcagata
     4441 aaatttaatt ttatctgact ttttcattta aaaatgctct cttgtgttgg tgattcagaa
     4501 tagtatggta ctcgtatttg agactaatat tggcaaacaa cataaagaaa aatataaatt
     4561 ttttataata aactgtataa aattttaata attgaccaca ataataaatg tattcctcat
     4621 aatattcccc caatattata gaaataaatt taagcgagat taaattcagt taatctcgct
     4681 taaataatgt ctaaatttat tattccaaaa aatcatcaaa atctaatgaa cctgattctg
     4741 caaaatcata taatgcattt tgctcaaaga aaaatttctc ttcaaattta atatagtcgc
     4801 tataattaga ttgacttatt tcattgatat aattgcaatc attttcgtta taagtaccaa
     4861 taaaaaactt atttcccatt aagtaatata tagctttcat atcattattt attatatata
     4921 cattttcttt tacatggtca ttattaaaat taaatctagt aaagaatata ccttcattca
     4981 tattactttt taacagaaat ggattttctc tataaaatac tcctgcaaat tcttcaggtg
     5041 aatttacact gtaaacactt acaaattcac ttttagaaat ctcatcaaat acctcaaaat
     5101 catacatagg ttctttatct gtcactaata gagaattaat tctaaaacca gtttcataac
     5161 acttacttat gcaaaaagca attttacata tataatatcc atcattatct tcatataaag
     5221 cttcacttat atatctgcct tgacctttat cacttaccac gtttttaagt aatgttccat
     5281 ttatattagt aatgtgcata tttgcaatct cgtcacttcc agaaaagtac tttaaacttt
     5341 ctctatccca tgctataaat ctcatggtca tatagtttat aaattcaact tcctcgtcaa
     5401 ctcttttaca tattttattg tataattttt ctatagttaa atctgtttta tagtttttta
     5461 taatatcaat atactcacat ttatctcctg gcaatagctt atcataataa agattcttat
     5521 taccaaaata agatactaaa aataaagatt catccttcgt taattcaact ctatctgaac
     5581 caaatcctcc catcaatctt tcttcttcca tataagcttc ttcttgtgtt gggttattta
     5641 aactcacata atccgctaat cctaatccct ctgcatctaa taaaaaatat tgacaaaagt
     5701 gattgttttc atcatctatc caatttatta taagacctaa actgcccata agtctagaat
     5761 ttgtagcctt tgcaaaatta aaattcatat agtcacatcc tttaaactct aaaatacttg
     5821 ttttttaata tataaattat tatacatata ttttaacaac ttagatacaa tttataatat
     5881 aatataagga aatgattaat tgaggtggtc ttatgaaaaa tatagcagct ttttttgata
     5941 tagatggtac tctttataga gactctctta tggttgaaca ttttaaaaaa ttaattaaat
     6001 acgatataat tgaccaaaaa aattggtata aacatgctag agacactttt atggattggg
     6061 ataaaagaca aggtaattat gatgattatc tattagaaat atgtgacctt tatgttgatt
     6121 cactaaaagg attagataaa acctgtatca actttacaag tgaccaagta attaaattaa
     6181 aagcagatag agtttataaa tacacacgtt caaggattga gtggcatcta aatcaaggac
     6241 acatagttat atttatatct ggtagccctg gatttcttgt tgaaaaaatg gcaaaaaaat
     6301 ataatgtaac cgattttcta ggaagtgatt atgtctttga aaacaatata tttacaggca
     6361 cagttattcc aatgtgggat tctataagta agaataatgc tataaacgat tttgttgtaa
     6421 agtatgattt agatttatca aactcgtatg cctatggaga tactaatggt gatataaata
     6481 tgctaaaaag agttggaaat ccaatagcaa taaatccaac aaaggaactt ttatctcaaa
     6541 tatcacttga tgaggaaatt tctaaaaatg ttgagataat agtagaaaga aaagatatta
     6601 tttattctct atctacagat gtaaatatag tggatattta atttatacta tctattttaa
     6661 aaacttatat tatatctaat atttatatct aacatataaa agctttgact aaaaatcaaa
     6721 gcttttatat gttgcactaa gaatatatta aatttagctt tatgctttaa tgtatattca
     6781 tatatatcat ttacacttat ctaaactaca atttcattaa aattaaatat aaaaatcaac
     6841 tattattttt taaatagcat ctttcttaat ctattattgt aataacctat aaaagaactg
     6901 taaacatagt catatactat aaaggctatc tcaaatgaac ctataataaa tatgtttatt
     6961 ggaatataaa ctattgttct taataaaaaa tacaatataa gtatcattat atttgcaaat
     7021 actaatttca taaaatactc aatatatata gacctatctt tttctataag atattttaca
     7081 ataccatata ttccaaaggt aagtgaatat acaatccatt gagacttact tgccatcact
     7141 ataaatccta aaactataga acctatataa aaagcaattc cactcttaaa gccccattcc
     7201 attattacaa ttgatactaa aagtgatgct aaccccataa taaacaatgt atttacagga
     7261 ataatgtttg taagagtcaa caatatcaca tttaatgcta ataaaactcc tccataagca
     7321 acttttatac tcatatttat catcctaaca acaagttatt aaatctccac caaaacattc
     7381 acaacatgaa tctaaacacc aaagtttagc acaattttca caacaatcgt cacctagaca
     7441 acaacagcaa tcatcacagc aacagcaaca acatccatct aaatcattac gtcttcttct
     7501 attataattg tcagccctat tgctataatc atttctatat tgtgtataac ttctaagtgc
     7561 atcactatat tcactatttt caggctccat aaattttgct ctttttaaga agtcttcacc
     7621 ttcttcataa tatcctatgt tcattgcaga aaaaccagtt aaataatacc actctgcaca
     7681 tttgtcagtc aaagttttta aaaaatcata tgctttttta aattcactat tttctatgaa
     7741 tgatcttgct ctcataaaat tttcattatt ataagtatta ctgtacattc tttccacctc
     7801 tactttctaa tatattaata tatcttaaat aaacaccaga ataaattata ttttctatta
     7861 ttccaacatt tttatttaga tttagattat caattcccct agctaaaaat cctaatgatg
     7921 ttactattat tttttttact ttttctttta actcatcatt tttatcaata tactctataa
     7981 atggattata tcttcctttc ttaaaatctt catctaaatc ttcataggca tctagtagat
     8041 atatatactt acctatatta aaacctatca ttcttaagtt tctctcattt tcatcttttt
     8101 tatagacaaa tacttcaccc attatatttc caaatatact agatacttca tctatattta
     8161 tatttttatc tttttctaac ttatttaatt catttagttg ttgttttata tactctgctt
     8221 tttcaggata cttttcatat gctaatttta atttgttttt atatatataa tatgccaatt
     8281 tatcttttat gcgtttatca tccattaaat tatcttccaa tttataatac gttaaaagaa
     8341 tattcatact tgctgcatat tctgtaatat catttgtaat tacctttttc tttttaaatg
     8401 gatttactat acacacttcc tctgtactta tagactctgg gttatatact gctgttaata
     8461 aaacaattaa aaatgttata tcatagttca aagaaaacct agagatttct ccatgatttc
     8521 tttttaagta tttacatagt ccacaatagt aagctttgta ataatcatat tctctaaatg
     8581 ttaaatccat tttgtttatt ttaacatatc caaacataaa tactcctttt tgtactattt
     8641 tttatttaga ttatatatag tataacactt tttatcaaga ttatataatt tacagtattc
     8701 taagaaactt aaaaaattcc ttctaatcat tgtatcttaa atttaaaata attagaaggt
     8761 tgggttaaaa ataatattaa attatatact tatattaact catacaagtt agttatgctt
     8821 atatcaattt aagttttaaa taattggtat atatttaaaa ctacctacag tatccttcaa
     8881 ttcttttttt gctttgttta taaccaattc atcaagcatt acatcattta ttgaacatga
     8941 tatagattta gatgccaata acattgcctt aaatcccata tcagaacctg cactggcaca
     9001 agattgccat gtatgggcag aaataccaat aggccaaact gaacaagaac actgtgctgt
     9061 aggaattatg tagctaacat ctccaatatc taatgataat gatatacagt tattatgagt
     9121 aaatgtatca tccgtaactt catcatgcag attcatctta gtaatatcct tatttccact
     9181 taatacacta gaaacactac ttcttttatc tatagacact gtctcagcta atttatctgc
     9241 aaaatagtag tcatcttcat tatagttttg cacacctact aatttcatat tttgtgatag
     9301 aatatctgtt aatattgtat ttggaatata gtcatatact ccacttataa tgtcatattc
     9361 cataatagta ccagtcatta atgctgctcc ttttgctata tcaacaatcc taccaaatac
     9421 atctcttaca tgctccattt taactcctct tatgtaatac cacacttctg caaaatcagg
     9481 aactatattt ggcatttttc caccattagt agttacatag tgtactctac aattatcaaa
     9541 tatatgttct ctcaaataat tacaacctat attcataagt tctactgcat caagtgcact
     9601 tcttccgtta taaggagctt gtgctgcatg ggcactaatc ccattatatc taaatttcac
     9661 agagtaatta gcaagtgttg gtattcttat tggagtattt atatcaaatg gatgccaact
     9721 aaaagcacaa tcaattccat caaaaaaacc tttttttatc atcaatactt ttccagataa
     9781 atcttcttct gctggacatc catagtattt tatagtccct ttcagctttt ttagtttgat
     9841 taattccttt actgcaatta cagctcctat tgaacctgta ccaagtaagt tatgtccaca
     9901 tccatgacct gcaccaccat ctacaatagg ttctttagta gtggatactt tttgagacaa
     9961 accatctaaa gcatcatatt ctcccaaaac tgctataact ggtctacctt ctccataact
    10021 agccacaaat gctgtatcca taccttctaa tccctctata ctaaaaccat gtttttttaa
    10081 acattctttt tgtaaatttg aagcatagta ttctttatac tgaagttctg gatttttcca
    10141 tatcttatct gatatatctc ttaattctcc ctgtatctca tctatatatt ccatcaaaaa
    10201 ctttttattt aaattatcca tattaattat ataaacctcc ctgtttctaa taacttatcg
    10261 attatcagcc aaaatgacta attttaactg atttaaaaat attttctacc atacaaccat
    10321 tttatacaat aaaacctctt gacttgtaag tttcatttta tcaagtaaga ggttttcaag
    10381 ttttataaaa tttttagcat gttaaccaat caagcatatt aacccataat ttattatagt
    10441 atttccaatc agtaaattct tttggacccc agtgaggtgc acagtcagaa ctaaagatag
    10501 cagattttcc ttttccaaac tcgccaacag ctacaaatgg gtctcctcca atagttgcta
    10561 aaacaggaca attatctcta gctactgttt tgttatatcc taaaaacttt ggccattctg
    10621 ttggtatacc ttttaatact ggatgttcag agtcaataac ttctggaatt attcctgctg
    10681 gtttttcaac tctatcatct ttatctatca ttgttattgg taatacatct ttgatagcag
    10741 tttctccaaa tctagctttt gcatctattc ctgtaaatga catatatcca cctaccatga
    10801 ttaacgcccc accattattt acatactctt tgattagttc aagtctatct ggattactat
    10861 tgcaatctat aaaagtacta ttagataata agaacgtatt agaacctata tcagataata
    10921 ttatacagtc atactcattt aactcttcta atttatacgg aaaactatct gctgctacat
    10981 gtgcaggcat atgaactgtc tcatatcctc cagattctat tgcttctttc aaccacttta
    11041 cagcttcttc ataatgagtt gtaacaaacg tatcaaaccc ttttatatga gttatatttt
    11101 ttacccaaga ttcccctact attaatactt ttttcattta tatattcctc ctacttttat
    11161 aagtttaata ttagacttgc atacataagt atactatcta aatactcctt aatttcaaca
    11221 tattcatcaa ttgaatgaca ttgttctatt gaacctggcc ctaatataag tgttggtatt
    11281 tcagctaaat ttttcattac tctcgcatca ttgccagctg ttgaaccttt tatctctaat
    11341 ttttttccta gagtttcttc tagtatttta tgtgcattca ctacaaaatc agaatccttg
    11401 tccatctcaa aacctaaccc tgattgatat atgtttatat ttggtttatt atctttaagc
    11461 cataaatctc cattagccct tgtcattatg acatttgtta catcatttac aacttgttca
    11521 taactcatta tatttggcaa gaagtgtaca cataaattaa atacacactt atctggcaca
    11581 gtagaacctg ctgttccacc atttattaca cctaaattta ttgtaggtga aggtaatagt
    11641 ggatgtttat atatcataag ccagttatgt tccaactctt ttatatcttg aagcaacaac
    11701 atagccttct caattgcatt tacaccctcc cacttactac cacagtgaag agacacacct
    11761 ttaacctcaa cttcaaagaa tacaaatccc atatgtgcaa ctattaagtt ttgttctgat
    11821 ggttcacaaa ttatgcaaca atctccatca ataccattca taactgcatt tatggtacca
    11881 tttccgccac cttcttcatc tactactgac attattttta cattaccagg tacatttaga
    11941 ccactatctt ttataagctt tacagctaat attgatgcta taagtccaga tttcatatca
    12001 gcagttccaa gaccataaag ttttccatta tcttctgtag cacgatatgg attatatttc
    12061 cacttactta tatcacccgg tggcatagtg tctacatgac cattaaatac aattgtctta
    12121 ccaggtaaat catcactata cttacaaatt aaattatatc tatcttgata attgtgacct
    12181 agatttcctt ctttatatat attttttgct tttttaatta attcttcgct catttcttgt
    12241 ctatccacac taaaacctat gtaatttgca agtttttcaa tatattcctg tccttctttt
    12301 tcaaatccac ctagtattcc atgaccaaca tcttcagtct ttatacttac aagttctttt
    12361 aaataatcta tgtattcttg ttttttacta tttaatgtat ctaagagaat ttttttcata
    12421 tttcctccta agatttattt ttacatttaa aatttcaagt ctaatctcat ctatttaagc
    12481 catagtaaac tttttcactt agcatattct cattcaatgt ataaagatgt atgcaaatta
    12541 aagtataaaa atatatacaa aaacttaata atttttatag tttataagct aaaatttaat
    12601 tactatttag atttagctga tttttttaat tttatattat ttatccatat agcaaataac
    12661 attaccaaac cttttataat catttgatta tatgaagata cacttaataa gtttaatcca
    12721 tttcctaata ttcctattat tccgacacct atacatgtac ctactataga accagaacca
    12781 cccatcatat tagtaccacc aagcacaacg gctgctatag catccaattc tgctccatct
    12841 ccaacagttg gtgaacctga tgccaaacgt gatgatagta ttatcccagc taatgctgtt
    12901 agtagtccag ctagtgcgta tacttttact ataactttat ttacttttac tccacataat
    12961 ctagcggcct cttcatttcc acctactgca tgtacatgac gtccaaaatt agttcttttt
    13021 aatagaaaat gtcctgctat tacaactata atcataatta taactggtat tggtattggt
    13081 ccaatatatc ctctaccgag catcttaaat gcatctgtat ttactgatat aggtcttcct
    13141 cctgtaaata caaagcttgc cccacttatt atcgttaaca tggctaaagt tacaatgaat
    13201 ggaggtagtt tttgtgttga aataattgca ccttttatga ctcctaatat tgtccctatt
    13261 gctaatgcaa gtatcatacc tacccatata ggtgcattat aattcactac tgttgtagcc
    13321 caaaatgtac ctactaaagc aattactgct cctacactta aatctattcc tcctgtaatt
    13381 attacaaatg tcatacctac tgcaagtatt gcatttattg atatttgtct tccaacatta
    13441 attaaattat ctaaagttaa aaagttagat gaagctacac tcattattat aaaaattatt
    13501 acaagtccta cagctgcact cccttggtct ctaaatacac ttgttaattt tgtcaataat
    13561 ggagaagatt tttcttcttt atgcttagtt attgaactca ttaattttac ctccgaaagc
    13621 caattttaat acattatttt caaccatttc ttcaccttct aaaaatccac ttatatgacc
    13681 ttctctcata accattattc tgtcactcat tgatattaat tctggtattt cagaagatat
    13741 cattattata cttacaccac tctccactaa atctcccatt agattgtata tctctgcctt
    13801 agcatttaca tctatacctc tggttggttc atccataatc aatatatctg gttgtaataa
    13861 aagccatctt gctattatag ctttttgttg gtttccacca cttaaacttt gtataacttg
    13921 attcatatgt ggtgttttta tctttaaagc ttctatgtat ttttctaaaa tctctttttc
    13981 cttttttcta tctataattg atttaaactt agatatcttt tttaacccag ccatagttgt
    14041 attttctttg acactcattt gtaaaaacaa tccagtacct tttctatctt ctgttattaa
    14101 tcctagtcca ttttctattg catctgatgg agttttaaac tttacttctt cattgtttaa
    14161 atatattttt ccagaatcat atgttctaag tccaaatata gcttctacta tttcacttct
    14221 cttacttcca actagtccac ctattcccaa tatttcacct tttcttatat taaagctaat
    14281 atcattaaaa acattgttct tagttagatt ttccactcgc ataatttctt cttttatttc
    14341 tacttttctt tttgggaaaa attggtctag ctttctatct atcattaaat taactaattc
    14401 ttcctcagac gatacatctt tggtatttaa agtcgaaatc gttttcccat ctcgcattat
    14461 agttattctg tcacaaatct caaagagttc ttccatccta tgggatatat atattatact
    14521 aactccactc tcttttaaat catttataag tctaaaaagt atttcagtct cttttttact
    14581 tattgaagaa gtaggttcat ccattattaa tactttagtt tctgatgata aaactcttgc
    14641 tatttctacc atttgttttt gagctatact aagctctttg actaaactat ttggatttat
    14701 atctattccc atattatcga aaatcttttt agcctcttca ttcatttttt tgtcattggt
    14761 taagactttg ccatttattt cttttcccat aaaaatattt tgtgctactg ttaattcgtc
    14821 aaaaactgtt agttcttgat atatggcatt tatacctatc tttttagaga tatctgggga
    14881 tatattctct atttctttgc cttcaaaaat aaattttcca gaagttttcg aatgtgcacc
    14941 agttaaaatc tttatcattg ttgatttacc agcaccattt tcacccagta gtgcatgaac
    15001 ttcgccatga aataactcaa aattaacatt atctaatgct ctgacaccag gaaattcttt
    15061 agcaatatta cttaacttca gaattatatt actcataatg acactccttt ttaaatagga
    15121 tttctttcaa ataatctcat tttattttac taattcttaa agtcttttat attttcctta
    15181 tcataaagta aagctggtac tggtatattc ttttctacct tttccccttt tatagctttt
    15241 actactgctt ctacagctaa acgtcccatc tctttaggtt gttgttgaat catagcaaga
    15301 atagttccat ctgttattcc acttgatgct tcttcagtta agtcaaatcc tacaatctta
    15361 acatccttat tttttgcaga ttcaagtgca gctttagctc ctagtacact attttcagct
    15421 gttgcatata ttatatctac atctggatta gattgaatta agttttctac tgtattaaga
    15481 gattcttctc tgtcatatcc tggttgtgaa tttaatatct taacatttgc tgaacctttt
    15541 aatgcatctt taaatccatc tattctctgc atttgtattt gagattttaa atctgtcact
    15601 attgctattt ctgactttcc acctaacttt tcatctatgt attttttagt gtattcccct
    15661 aattttttac cagcatcata actaactgtt cctacataac ttgtaatatt ttcagtattt
    15721 aatacagcat ctactgtaac tactggcatt ttttcaaatg ctccttctac tgctggtact
    15781 atagccgaat tatcagttcc aagtactatc attccatcta cattttgttg tataaaatct
    15841 tctattgctg atgtttgctt agctacatct tggtctgggt catttactat aactttcaca
    15901 cctaattctt tagctttttc ttttattccc tcatcaatat ctataaaaaa ttgatgttga
    15961 agagttattg tagatactcc aatagttaaa tctttcttgt ctgaaccacc tttattatct
    16021 gatttacttg gtccttccat tgaacaccct gttaacattc ctattgctag tattccagca
    16081 attcctaaag ataaaatttt tctcactctc ataattaacc tccattttta atagttttaa
    16141 atttgaacaa attagatttt tatttattat ttaaatattt ttcaacatct tctttataag
    16201 gcataccaga ttgtgcacct agtttagtta cagacagacc tgatactact actgcatatt
    16261 ctactgctgt atataaattt ttcccttctg ttatagccac tgccaatgct ccattaaatg
    16321 tatctcctgc tcctgtggta tcttgaacat caacacttat acaagataca tgcttgattt
    16381 cctcaccatc ataaaatcta gctccatttt ttccttctgt tattacaagt ttatttggat
    16441 atttttttaa tacttcttct atcccttcat ttgtgtcaaa aactatctta tattcatgtt
    16501 catttggtgt taagtaagtt actttttcta ttatatcttc atttagtttt actgctggtg
    16561 ctggatttaa taaaacccta atcctatttt caaaacagaa attcactaca taatttattg
    16621 tttttaatgg aatctctaat tgtagcaata ctatatctgc attctttatc tcttcttcat
    16681 tctttttaat taattctata tctactagct cattagtccc tggtacaaca acaatactat
    16741 tatcattttc acataatgtt ataacagcaa caccagaact tttgtgatta tttctggata
    16801 ctaagctata atcaacttta ttcgttctaa aatttcttat taactcctct cctaagccat
    16861 cttcccctat gcatgatatc atttttacat ttgctcctag tttagaagct gagatagctt
    16921 gattagcccc ttttcctcca ggtgatgtaa aaaaactatt acctaatact gtttctcctt
    16981 tttctggtct tttatctaca gaacatacca tgtccatgtt tacacttcct atgacaacta
    17041 tgtttcccat tacattactc ctttacatat ctatttatgt ctctcgtgct gttattcact
    17101 ttcttttgtt gaatctctta tgaccaattc tggtttgaaa atcaattcat caaacgattc
    17161 ttttttatct cctcttaaac aatttatcaa tatttcactg gctttatatc ctatatcata
    17221 agacggctgt tttactgtgg taagagaagg gcttattaga cttgatgttt gaatatcatc
    17281 aaatcccacg acacttatat catttggtat acttaatcct ctttctttaa gacctcttat
    17341 gacacctatt gcaatcaaat catttgcaca aaatattgca tcaaaatcta tcttttctaa
    17401 attttttata aattcttgtc cccattcaat cttatatttt ccttcaaata cataagcagg
    17461 attgtagctt aaattgcact cgattagagc ctttttatat ccttctaatc tatctactgc
    17521 tatttcattt tgaagtggac cacttaggta tattattttc ttatttccaa tatctaataa
    17581 atgttttgta gctatatagg ccccttcaaa gttatttatt ttaacaattc cttttaaggt
    17641 ttctttgttc atacttatct tcttatcaat caagacagtt ggtattttta tatctttata
    17701 atttgcttct ttccagtttg tatttgaaga tgctgcaaat ataattccat ctatcatcct
    17761 ctctgatagt gttcttattc cttcatattc ttttttagca tcttcatctg tattacataa
    17821 aattatattg tagccttctt cattagcttt gtcttctaca cctcttgata catctgtaaa
    17881 gaatggattt cgtatatctg gtataagaag ccctatagta ttagtttttt tagttactaa
    17941 actttgtgct aatttatttg gtacataatt tttttccttc attattttca aaattttttc
    18001 tcttgttgcc tgacttatat tttcatcttt attattaatg acttttgaca cagttgtttt
    18061 agaaacacca gccaattcgc caatttcttt tatagttata ctcaagaagt tcacccccaa
    18121 aatttaggaa accgttttac ttaaccggtt acctagatac tatcacatct tttttccatt
    18181 tgcaaccatt ttatataaat tttgatattt ttcccttttt tcaaaatatt gcaacttata
    18241 attcaatttt aatatttaaa ttaatctgaa aaaaaaatta atatactttt ataattatct
    18301 aaaagtatat taattaattt aagcagtatt tattaaagtt caaatccttg ctctataatc
    18361 atttttttat cattttcaat cccacttcca acagttgtca aataatcacc aacaattgca
    18421 gaatttactc ccccattaaa tccaactttg tcatatccct ttaatgatag ccttccacca
    18481 gcatacctta tgtacacatt aggaattata aacctaaata ctgctgttgt ttttagtatt
    18541 tccattggtt ctaatacatc ataattttcc attggtgtat tcttaatagg atttaaaatg
    18601 tttattggaa atgattttac atttaattct cgtatttcaa aagccatttt tagtctctgt
    18661 tcttcactct cattcattcc aattataccg cctacacata catctagccc agctttttta
    18721 gcatctttta tagtttttat cctatcttta tatgtgtgtg ttgtacatat attatgaaaa
    18781 ttatctctac acgtctcaac attgtggtga tatgtagtca cacctgctga cttcaacatt
    18841 ttagcttgct cataatctat aatacctaaa gatgcacata attttaaatt agtattttcc
    18901 ctcaatcctt catagatatt taaaatatta ttaaactcct ttcctgacat acctttacca
    18961 cttgtaacca atgagaatct atgcactcct ttactctcca tctctttagc tctatttaag
    19021 atttcattgt aatctaataa tgaatattct tctacaccag ttttataata agaagactga
    19081 gcacaaaatt tacagtcttc actacatttg ccagatttag cattcattat cgtacataaa
    19141 tctgcttttc ttcccataaa atattctctt atttcatttg cagattttaa tagaatatca
    19201 aaatcgtttt tattatttgt atcaaggctt attaaattaa gagcttcttc ataacttatt
    19261 tctttttctc tcaatacttt attttttaat tttattatgt atttttccat atatcctcct
    19321 atttgtcaac ttaatatttt tatgtagttt acttattata tatagtattg catatataac
    19381 atttattggt caactttatt ttagacacaa gtttactata cacaaaaaaa tactgcttca
    19441 aaacaatatt agtatataga ttatacatat tattattaaa gcagtatttt ttattagaat
    19501 ataattctta ctggtttata aaactatcct tgtcttaact ccatccaagc tttccattgt
    19561 aataacttct aagccttcat attctctaaa tagccatttt aaatccttca tggcttgatt
    19621 aacctgactt tttgttagat tatttataaa atattctttt ctagtttcct catactcttt
    19681 gctagtcaaa aagtttctta gaaaattaaa cgcaaataca cttggaatat tgtttacatt
    19741 agccttcttg ctgttttcct tctcatagta aattttcata aatgcatact cctttgatac
    19801 ttttagattt ctcttacaat aattatatgc atttaagtgc tactattctt ataattttat
    19861 taattcatat tctttacttc ccatacccat ttcacatgca tagtctatta ttctagttcc
    19921 atttacatga ggatgttcat gtttgaaaac atcatgaccc atttccttac aaatcaaatc
    19981 atagcatgct tgttcaatag ctacagggtc tgttgatgct aatattccta tatcatgggc
    20041 aattggtcta cctgaccaag gtacacaatc acaaagtgga gttacattca taacaaaagt
    20101 tatataccct accttgtctt ttttatttga tactgctcca taagcgtatt ctgccatctt
    20161 ttcgacaaac acatctgagt cactttccca ttgtatagtt actgctctag ttggacagac
    20221 agttggacat tctccacatc cataacatac atcagaatct ataactgctt ttttatccac
    20281 tatacttata gcttttgtag gacaagaatt aacacacttt ccacaaccta cacacttctt
    20341 ttcctttact actggagtaa catcagaatg ttgcatttgt tttcctgctg cacttgcaca
    20401 tcccatagct aagtttttta atgctcctcc aaaacctgct gcttcatgac ctttaaaatg
    20461 actcattact atcattgcag aagaattata aatttctcca cctattttta cactttcaaa
    20521 atgttttttg tctattttta cattctcata atttctacta tataatccat ctgcaattat
    20581 tactggtgca tttacaactg cataagcaaa tccattttct atagcagttg taagatggtc
    20641 tacagaattt gttctactcc ctgtatacag tgtatttgta tctgttaaaa atggctttcc
    20701 ttcgcagtct ttaaccttat caaccacttg tctaactgcc acaggactca tatatgtagt
    20761 atttcccttt tctccaaagt gaagtttaat tgcgacttgg tcattttttt ctattaaatc
    20821 tttgaatcct gcttcatcaa ataatcttct tacattgttt ggtacgtttt tattttgcga
    20881 atttgagtat aaatcacaaa aatatacttt tgacttttcc atatctacac ccctttaaaa
    20941 tatttactta tactaatttt atcactttta aagtaatttt tagtatattt taacataatt
    21001 aaatattctt atatttattt gatacaaata atattatttg tattattttc tacacttaat
    21061 tctatatatt aaactacacc taaaaatcaa aaagacttga aacttaagtc caagtctttt
    21121 tgatttttag gtgtagtttt taacaacata agattacttt accttgtgat aaaggtatta
    21181 ttaaactggt tttttattaa ataaaataac agctgctagt aaacatacta tagaaataag
    21241 aactgttata ataattggaa taataaattc tggcattgcc actttccctg aaatcaagtc
    21301 tatatttttt gacatcaaga aattaggagt ataaggtgca atctgtttag gaatagaaat
    21361 taaactcaat aagagagttg ctaccaatac aagtaaaaca ctggcaaatg ctggtctaaa
    21421 tagtacacac ccaagaatta atacactaat atacataatt cctataagcc ataaattaaa
    21481 tgctgaaaat ataatatgat taagatttgc agttggccaa aaatacattg tatagccata
    21541 agcaaataaa aaactcaacc aaaaaccaat tgtcataata atcaccgtaa cagagaattt
    21601 agacaatact atagatgaac gtgataaacc tttagtcagc ataataacaa gtgtcccttt
    21661 agaatattca tttgataaaa tattacaaaa aataattaga gttaaactca taccaagacc
    21721 agagatattg ctaaaaaatt gtgtccaaga atctaaagca gttggtgcag cagtaacttt
    21781 taaagtcggt gcaaaatgag caatcaagtc tggcataaat tttgcagaaa taggactact
    21841 tataccaaat attagaaata aaataattaa actaaataat ttataatttc ttaaattctc
    21901 tttaaattct ttttttgtaa atgctatgta ttctctcact ttactacctc caaaaataaa
    21961 ttttcaagtg ataattctat tagttccatc tttactggac aaagattcat ttctgcgagc
    22021 gtagatataa ctgttttttg tattgctttt atatctttac catgcaaaac aatttccata
    22081 ttagtttctt ctgaatcttt tagtaaggat ttaataccat cactagactt aaacttttga
    22141 atttcatcat tacttgcaaa ctccagtaaa agtctatcct ttccgtgcat actttttatt
    22201 tctgaaagtg taccactaag ggcaatgctt cctttgttta atatagcaac atggtcacag
    22261 attctttcaa catctgatag tatatgtgtt gaaaatatta cagttgttga gtctttgatt
    22321 ttaagcataa tatctaatat ttcttttcga ccaacagggt caagtgcact tgttggttca
    22381 tcacaaataa gtaatttggg gcgtgaaagc aaagcttgag ctataccaag tcgttgcttc
    22441 attccacgag aaaacccacc tattcgtctc ttttcatttc taagacccac aagtgataac
    22501 aactcttcac tccttatctg tatttctttt tttgaaagtc ccgtaatttc accacaaaga
    22561 gaaagatatt caagtggtct catataattg taaaactctg gaacatcagg cagataacct
    22621 acatgacgat tagaacttgt tttcccatag gtcactttct caccacaaac atctatagtt
    22681 ccactatctg gtttaagtaa cccaagtacc attttcattg ttgtagtctt acctgcacca
    22741 ttcttaccta caaacccaaa gactgaccct tctggtacag taaaatttaa attatctatt
    22801 atctttcgat taccaaaacc ttttgataat ccatttattg agacaatatt catcattctt
    22861 cacctcttcc tattgtaaaa tacaaaattg gtcctattaa actaataaac agtactacaa
    22921 taatccatat tgccttattt ccaattttat aatttggatg tctcaacaca tgaacaagtg
    22981 cagtaattat aagtattaaa tctaaaataa taacaggaac caaaagtggt aagtattcca
    23041 tcaaattttc cataatctta ttcctccaat aaagataatt tttctataag aaatttgtat
    23101 tctttgtttt cacttaatac agaaaacatt ggattatttt taatagcagc aacaatacct
    23161 gcttttacga ttgtatcatc acgtgtaata cctgttccaa tttcagaaat ccatctgtca
    23221 agtttattaa aaaagtcatc cccatgtatt ataattgggt atatatcacg tgttgctaaa
    23281 tctacatatt ttcgtaatga tttaatagct ccttcattat caccatgtat taaattaatt
    23341 tgtgcctgtg ttaaatatga agaaagcata atagcaggag ataatgtatc aagctcaaat
    23401 atatctgaaa ttgctagaat acgtctttct atttccttca tttgtaattt atctgcattt
    23461 tgcaaaatac ccactagatt ttggactaat gatataaggt tctgatatgc accaagttga
    23521 aatgtttctc ttgcttcatc catttgacca ttcatcattt gcccttgtgc aagaagtata
    23581 gattcattta tcatgggaaa attgctgttt tgcaataaat caatcacttg tatgggttga
    23641 tttaacaata tataacaagt tgcctccata ctttttgctt gacggcaaat atctatgtca
    23701 ttacaagttt cctgtatacg aataaatatt tctaatgctt cactaattaa tagttcacgc
    23761 tttttttcat ctacaatatc atagtgatta actattaaaa gacccatccg aaaaatcaaa
    23821 ggaaaacatg aataatattt ttttatgatt tctcttattt catccatgac ttcatcaaat
    23881 ggtttaaccg taaagtcttt gcacagttta ttatacagtt tattaatatc ttccttcatc
    23941 atttgaggtt cataacatat taactcatca acggtaatgt tgaaatatgt cgcgagttgc
    24001 ggtaaaaagg ttatgtcagg atagctttgt ccagtttccc atttagatac agaagcttta
    24061 gaaacgccta tataatttgc aagttcatct tgtgtaattc ctttttcttt acgctttaaa
    24121 atcagcgttt ttgcgatgtt taattcattc atgtcaatcc ctccttatgt ataattatat
    24181 ccttaaacat gtaaagctaa caagcgattt gaagttgact tttgacgaaa aaatcaacca
    24241 cagagaaaca aataaacaag tatataaaat atatatttaa atttatcttt aatctccttt
    24301 gtaaaatatg taaactttgt aaataaaatc catattatat aaaactaata gttaatctat
    24361 ctaaatacag tttttattta tcacgttttt aaatattttg tgtaaaacct cttttaatat
    24421 aaacacctta ttttcatttc tcatttcata ttctttttaa aatactgaat ataactcttc
    24481 gattttccat ttaatccttt tataaagtta ttattcgtat ttattcctct aattataaca
    24541 ggcaactatc atgtattggt atttgtctat tatataaaaa tctataaaag aaaagcagtc
    24601 aatcatttag attaactgct tgtacatata tcttattaaa ctgtataaac tataattttt
    24661 attattctcc attttcatcc caagtcataa atccccatcc actatctgga taaatatcga
    24721 tagacttttc tctaatcata taaccaactt tataacactc ttttgttatt ttattagata
    24781 gtatacatcc ttctccattt atctaattcc atttaattaa cttttctttt caaccttaac
    24841 ttttataaaa tcatcttttt taataatttc atacttattt tctcttcaac atcatcaaat
    24901 gagggtgtct caaaattaac tttttacttc ataaggcact cttttttgta tgaagtaaaa
    24961 tatattttca tcatttcaac aataagtaag aggcttatct ctattttgag acagccccat
    25021 ttgatggtgt tgaacattta aataaggttg aactcgtttt atctctcttt ttaagatatc
    25081 tgtaaatttg cacataaagt ctcttcttct tttacaattc taatagtttt attaaagcca
    25141 aagtatatat ctccatattc tttcgtatat gatttattgg tactctttca tctactccat
    25201 gaccaccagt tttatacgct aagaacttag gtccaaacgc caccatatct ttaaaccaac
    25261 ttgcatatgt gccaccaccc atagcaattg tatatccatt ttcatctgtt acttcttcat
    25321 aggcttctaa taatttttta agtactaaat tactctcatc cacataatgt aagtctttat
    25381 gaacaataac ctctattttc caaccattac aaaaaacctt tttgaatcta tctattatat
    25441 tgtttaaaac tatattttta ccatacctta tatctaactc acatacgatt ttttcctcat
    25501 ttacttttaa tattcctaaa tttaaggtag tgtttttgaa tacctcatca tattgattaa
    25561 tccccaatgc atctccataa taatcactac aaaggtattt tgaaactaat tctatatctt
    25621 ctctatgctg aaaatccata ttatcctcaa ctatctttat taccatttta gatatagcat
    25681 tttctccctt ttcaggatta cttgcatgta cagctactcc tttagtagtt aactctgaaa
    25741 taattccatt aataattttt gcagtacaat gagatggaac aacattttct ttagttcctc
    25801 cacttactat tatgtaaggt ttacttttgt caattttaat ttctttttct atccttatat
    25861 gaacccttcc tttttctcca ttaaccactg gatacatagc atctggagta aatcccatac
    25921 ttggaatttc ttcaccttta tctaagtaat atttgataca tttcatacct gtctcctcat
    25981 ttgtaccaaa aattaatctt attcttttat taattgtagg atacatatcc tctatgtttt
    26041 tcaatacatg tataagcata gatacagcac ccttattatc tatgacacct cttccataaa
    26101 taatattgtc aattactgct cccgaaaatg ggtctacact ccacccctct cctggtggaa
    26161 ctatatctaa atgcattgga atccctatta attcctctcc ctctccaatt tctgcatatc
    26221 caatataatt atcaatattt ttaacactaa aacctaaact agcacagtaa tctaaagttt
    26281 tatctaaaga ttttttaggt cctataccaa aaggacattg tgaaataggt tcaccttgtt
    26341 gtgaatcaat ttttatcaat tcttttagaa attctatggt tctatttaaa ctattatcta
    26401 cacttctgct tatatccata aatcaaccta ctttctatct ttttaaagcc tgtccttaaa
    26461 gaacaggctt ttagcattaa aaattatttt tttgtaaata ctaattcaca aacttcatca
    26521 tcatgagcac atttttgagc aaaatctaat ttaacacctt gtgcacagtc aactcttcca
    26581 taatccccat aacaagctaa tctacaaatt tcttttcttt cttctttagt taatccatat
    26641 tctttccaag cagcatctaa tggacagtga tggaatttta aaacgccatt ctcatctgta
    26701 ttttctacta attccatttc aaacactttt tgtcctttac tgttatataa catttctgcc
    26761 atttttcctg gagtatctgc tacgttatat ttttgacctc tcattttacc aaatccatat
    26821 attgcttctt tacatatatc atctggatta gctcctaatt tttcagcttc tttcataaga
    26881 agatagaacc atactgctct ttctcctgtt gctcctctaa ttccttctaa atattccttt
    26941 tctgtataca ttttttctga catttctttc tcctcctaaa attaaattct atattttaat
    27001 cactgtgaat tagaatattc caatgaatga ccctaccaat gctaatacaa ccaaaattac
    27061 taataactta gttattgtcc acttcttgta tttcattccc caatatacga agaatacaac
    27121 accaagtggt aataaacctg gagcaatcat atttaatgta tcttgaacaa caattgcttt
    27181 accaccaata tcaaatgata gcggagttga aagcttaact gtagttgcag ataatgctcc
    27241 catcataaac attcctagaa ttgaagcacc atcaattatc ttattgacaa taccacctga
    27301 tagaattttc ttaattgaat ctctacctaa agaatatcct aaatgaaata agtaataacc
    27361 ttcgcaaaat agtaatatac taaacattat tgggaaaaat gcacctataa cacttccttc
    27421 tgctccaaat gaagcaccta aagctaagaa tattgtttga aatgtaccaa aatctaaagt
    27481 atctccaatt ccagccaaag gtcccataag accattctta acacctgaaa taacttctcc
    27541 tgggattttt ccttcagtag ctttctcttc ttccatagct aaaactgtac cgtgaattaa
    27601 tcctccccat atagcttgag tattaaaaaa ttgtaagtgt ctctttaacg catctactaa
    27661 atcttctttt ctcttatata acttttctaa agcaggagtg aaacttgcac aaactgctaa
    27721 tgcttgcatt ctttcaaaag agttggataa ttctgctgtc caccaccatc ttagatatgt
    27781 ttttgttaca tctttctttg taagtactct tgtcttatta acttcagttg gaccttgtcc
    27841 atttttaact tctttatttt ttatttcttg cattatactt cacctaccct tttgtcttct
    27901 ttcataaagg taattaaaag agctatacaa acaccaaata ttgcagctgc agtaattgat
    27961 atttcaaaat attgaaccat aaaaaatcct ataataaaca ttggtaagaa tttattttta
    28021 cctatagtaa atattgttgt tgcaaaacct aatgcaggta atataccgcc cattactgtt
    28081 aatccattca ttaaccattg tggtataaca tctaataatg attgaactaa atctgctcca
    28141 aaaaagttac atacaaaaac tattggaaac cttaaaacaa acccaaatat taaagaataa
    28201 agtgttgcac atctccagat gccttttgta ttaccttctt cagcatactt atctgcctta
    28261 tgaaccaata cagcattacc agttcttctt aagttattaa ctaatactcc tataacacct
    28321 aaaggtaccg caatagatac tgcaacttct gcattaacac cagtttgaag tgctactggt
    28381 attgcaataa gagcagctag acatttatct gatggaatat ttccccctgc tgcgaccatt
    28441 cctagataaa ccatttctat acttgcacca acaatcatac cagttgttac atcaccccaa
    28501 agtaatccaa ggctaaaacc tataaataaa ggagacttta gtgttgagaa aagggtatac
    28561 cctgcaagac ctgctgcaaa ccaataccat aatcctgtta caattgccaa catcaaaaca
    28621 gattccattt ataattcctc ctaatttata ttttttattt aaatttcttt aacgcatttt
    28681 catatgtcat agatgattcc tctggtataa cttgtaggac tatttcaacc ccattttcat
    28741 taagttcatt aagttgttct acatcctcat ttcctaatga aacagctgta aacaccattt
    28801 tctttcctgc ttcatttgga atacctccta attgaatctt ttcatattta agtccagctt
    28861 tataagcctt atttgccata tcaacatttt taaatagaat aaatatattt ttatctccta
    28921 aagtgttgtt ttggaatgct tgtcccgcat cttctgctgt taaaataact acttctactc
    28981 ctgatggtgc tgccatttta tatatgtcag ccataaattc atcttgacct aagaagtcat
    29041 caactattat tattttttga gcttgagcga tttttaccca ttttgttata acttgcccat
    29101 gaattaatct gtggtctact cttactaatg ttatttttgc cattatattc acctcataat
    29161 ttatattttt ttaaattctt taattaaatc cacacaaagg ttattatttt ttttgacgat
    29221 tctttctggt aatgtatgta atttatcttc tttgcttaat tcttcatcta cgattaaaat
    29281 tgtctgtaag ctaagtccat ttattgcatc tattcctctt cttatagcaa cagctattgc
    29341 aacacttgat gtagatcctc catataaatc tgatattata attttcacat cttctttatc
    29401 tactacttct tcaacctctt tcataaatac agaaacatct ttttcagaac ttagtgataa
    29461 aacttcatat tgatttgaca atccaaagtt tttatttgtt tcttctacta agacttttcc
    29521 ccaagttcca tggcacagta tgattacctt atatttattc attgctaaat aaactctcct
    29581 ttatagcgat taatattttg gtttaattct acttcttctt catcaggtac catttgaatt
    29641 gatacattaa tattcttttt aataaattca tctattaaaa gaaactcttt tttattaatg
    29701 tatacatttt gagatatttt cttttttcct attcctgtag gtattcttcc aacaataagt
    29761 tttttgatat taatcccttc ttctatcatt ctatttgcag tatctaaatt tttaattaat
    29821 acaaaaacgt tatcatcagc ttgattatta taaaaatatc tccttgattc acttacagtt
    29881 aatattgata aatcaatatt ctttggtgct gccattttta tcaaaccttt agcaataaca
    29941 tcattggttg tttcatcatc tactactact atctttttta cacctagatg cttaacccat
    30001 ttatatataa cttgaccatg tattaatcta tcatcacatc tgcaatattt tactaaagac
    30061 atttttaatc aaactccttt ttctattaca ttgagctaag aactttatta atattgttta
    30121 taccagtttg tcctgcttca atacatgctt ctgctaactc ttctaaactt tttccctctc
    30181 tattaattaa agcttcaagt agcattggaa gatttactcc agtaagtgca tgaaacttgc
    30241 cacctttttt aaggtttaaa cttgcaacat tacttggcga acctcctaat aggtcagcta
    30301 atactaaaac tccgtcacct tcatctaatt catttaactt ttctacaaaa tttttattta
    30361 agtcttcaat attatcattc ctatttagtt taattgctgc tgttctttct gctggtcctg
    30421 caataagttc acagcttttt ataatttctt cactaaaact cccatgagtc ataactatta
    30481 ttcctatcac caatttcacc tcacttttct tgtcactttt tatataagca attgccgtgc
    30541 caacttatgt gtatcaataa caaatggcta ttttacagga tttaatcaaa actttttact
    30601 caattttttt taaaaactta ttatttcgat atgtatcaaa agattttttc aacctgtatc
    30661 aaatctgtat caaaaaaagt aaaaaaaaga tagccttttg gctattttta aattttgtat
    30721 caacttttga atttatctgt atcatattgt gattcaaata tatctaatat atttgcatat
    30781 tccatatctg aaataattat atcgaatgtc tcttctacta gcttaaaact ttcttttata
    30841 actaaatata attctttatt tctactaatt ctttcttcat atgatttata aactaaagac
    30901 tcttttatta ttactctttc aatcatacat gaacaatgaa atataaactt tactaaaagt
    30961 tcatcttgaa ttactaaaga atagtgttca ctaattctat taattacttc ttttaatata
    31021 aaataagcct tttccccatt taaaaaagtc aaagttttac taatattatc aattagtaat
    31081 ctatcaaaat atctaccacc attatctttt tcagcatatg taacttccat atctccataa
    31141 tgtttcttta tagattctat aatattaaaa tataatttct ctaatgtcat ttctggagtt
    31201 agagcctttc tagttgcttc tattacaata ggtgtactta ccatatctat tgcttttact
    31261 tcttttcctg tagcatcacg aataacttta gcaaatgtta aaatagaccc catatcagtt
    31321 aaaattaaaa ttccctttcc tttatcaatt ttattggcta tttctacagc ttgtactaaa
    31381 atatcctgaa ctctatcttc taatcccata ttaattgcca ctgcatggtt acaatccagt
    31441 aaagtattgg ctacattcac catgctagat gctgtagatt caccatgcat tatgactaat
    31501 attgctatac tctcctcatt taatcccaca tacgataaat aaagaaatgt tgctaaaaaa
    31561 attgcttcat cttctggaaa ctctactcca tacattaatg acatgttaga taatatttct
    31621 tttgctatgt tatattcata tgctctttcc ttcataattt catctttatt aggatgcttt
    31681 actatatttc caatctttat tctttcaatt aaattctgaa tatgtaaagc tatagctttt
    31741 attaatttat ctaatccttc tcttttgctc catttatcat gcttttgtaa aatatatttt
    31801 acagtagttg caattgaatc attaacaatg ttgttataag ctgtttgatt actactatta
    31861 tatataaaag tattcattaa attataggaa tacttctgta tgtctccatc tataacactt
    31921 ctaatttgtg actctttaat accttcttgt tgaagtttat tccaagtttc ttttatcatt
    31981 ccataaaaat ctaaatcata ttttttattt tctattaata aattttcact ttcaaaatcc
    32041 ttttcttctg gtaaaaaaat aatatcatct tttccaataa aactgaaatt ttgtacaaac
    32101 tcctcttttc tattatttcc atataatgat tctctaatat tatttggtag aagagagagc
    32161 cttacatata cacattccct tttataggtc atataatcta aaaaagctct tgcacaaatt
    32221 aattgtatat cgctttttaa ttggcctatg tttcccttac acttatataa aataaatgcc
    32281 ttaataactt cttttgaaac ctttaactta acaccaatcc taacactctc ttctttaaaa
    32341 aaataacata taagcttcat tctctcttga aagcctcttt cctctaaaga cggaatcttt
    32401 atagttacag gtattcttct taaaaacgtt tccaacattg ctgtttctgg gtcttctgta
    32461 gtggctgcaa ttatcataac tctacactcg tgtaccttat tagcctctcc taaccttcta
    32521 tatatccctt tatccataag cagaaatagc atttcttgtc cctctgcaga taatctatga
    32581 acttcatcta aaaacaatac tccattatta gcttcatgta caataccata cttatcttta
    32641 tcagctccag taaatgctcc ttttacatat ccaaaaagct gcgctaataa taattgctga
    32701 ttatcagaat aatcagcaca gttaaatatg ataaatggtg cattatcact atcttctttt
    32761 atagttaaac tatacttata catatattct gcaaatatag atttaccaac tcctgtaggt
    32821 cctattatta atgtactcaa ccccttaggt ggatatatta ctgctgcttt agcctgttct
    32881 atttgggacc ttaaacttcc atcacatcct actaaattaa aaatattgtt ctcttttttt
    32941 atactctcta aaatatactc atctttgata gaatcatttt cactatattc gtttatagag
    33001 ttaatattat caaatatccc tttatttagt ttctttccta aaatactctc aatactttct
    33061 ttatataagt actgaacagg cttacccttt atctttataa taatactttc ttttattaat
    33121 tgatttaatt ccttactagc attacttcta tttataccta cttcagtagc tatatattct
    33181 gcatcaaatc caaatctaat gccattatta aagttcaagt gttcttctgt taaccttttc
    33241 aagcaaatta aaactttttc tttccttgat agcttctttt gtgtcatagt taacctcccc
    33301 tataagcagt aatactgtta aacatttatt attaagctta attctacaat attttaatat
    33361 ttttgtctaa ttatgtaact attgattttc tttcctattc gttttataat ataaattacg
    33421 ttaccctcat cttttataga ggaggaattt atatgaattt tttatcagat ttacacaccc
    33481 actctatagt cagtggtcat ggctatagca ctttactaga aaatattaat tattgtaaag
    33541 aaaatggaat taagatacta ggtacatctg aacatggtcc taagatgcct ggttctcccc
    33601 acagatggta ctttcacaac attcaaaata tcccaagaat cataaataac attataattt
    33661 taagaggctg tgaagcaaat atactagata ttaaaggaaa catagaccta gagccttttg
    33721 taattcctcg cttagattat cttattttgt catttcacga agctgtgttt tctccaaata
    33781 cattagagaa taatactaaa gctttaataa atgcaataaa taagcatgat aatattgaaa
    33841 tattaggaca ccttggaaac ccaaactacc caatcgacta tgaattaatc attaaattag
    33901 ctatagaaaa gaatatctta atagaaataa ataattgttc tattaaaggc gtgtcaagaa
    33961 atggtagctc ggataactgt aagtatattg ctacactttg caaaaaatat ggtgctaaaa
    34021 tcatactgac ttcagatgct cacatttgtt ttgacatagg taactatgag tattctgaaa
    34081 atatcttaaa ggaaattaat tttccagatg aattaataat gaattatcct aaaaaactta
    34141 ttaatcattt tcaccaaaaa ggtaaattac tagatgttga ttatacaaat atctaagtaa
    34201 taatacatgc ttactttaac tcccataaaa attttaatac tatttatatt atatgaaata
    34261 aagaaattat aataaagaag ctatttaata aagcttaatt acttttatga acttgatgga
    34321 ttgatatggt ctatgatagc aatagaaatt ataacatttt taataaactt agttttatat
    34381 accttatagt ataaatctaa aaaagcatca tctaaaaagg agctgtcaca tgagcaaatt
    34441 aaatttgttc tatgatagct ctttttttac ttattttaat taggtatatt tttaattatt
    34501 ttatataaag cttatgttct aagtaaaatt atgcataaca aacaaaggta taaaaatacc
    34561 attttttcag ataatattta attataaata ataaatttag aatacttctt ttaaatgatg
    34621 agagtctaga aatttttatg tgtattcttt aaataaaaat ttccagactc tagccccttt
    34681 ttgaatattt taaaatttaa cttaaactaa gcaaattcta taatagctta tctctaaata
//
LOCUS       DAMJVG010000040        33772 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.040, whole genome shotgun sequence.
ACCESSION   DAMJVG010000040 DAMJVG010000000
VERSION     DAMJVG010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 33772)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33772)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33772
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.040"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            256..702
                     /locus_tag="PC512_002069"
     CDS             256..702
                     /locus_tag="PC512_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441811.1"
                     /translation="MAISDLAFGTECLKTSFQMLFSVISLVNINLLQAQILIAIGGLI
                     SILAMVSLTLFLSAKCKDSLTSMLIAFSICLIPMGIGVSWIGYLLPPGGIGFKISLLY
                     QMTSFNFLHLGGMSFWTPHIILFFSVIEIPIFIFLAIRTYCKHQVP"
     gene            1083..2000
                     /gene="pstC"
                     /locus_tag="PC512_002070"
     CDS             1083..2000
                     /gene="pstC"
                     /locus_tag="PC512_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HDF2441812.1"
                     /translation="MIVKSRLVGLEKNDNNGNKTKYVIEKVAKNIFLLSALVAVASLL
                     LIIGFVFYKGLRPFIFEGYSFIDFLTGADWVPSANKFGISSMIVASIFATLGALVIGV
                     PVGILTSVFIAEVAPKRLAKIMSPAVELLAGIPSVLYGVFGLAVIVPTIQGIFNLPKG
                     QSLLAIVIVLAVMMLPTIISVSETAIRAVPKAYKEGSLALGASKIETIFKVVLPAAKS
                     GVLAAVVLGVGRALGETMAVILVAGNSPVMPTAITDSVRPLTTNIALEMGYAFGTHQE
                     MLFATGVVLFTFILILNLVLNKLSNKAVN"
     gene            2002..2826
                     /gene="pstA"
                     /locus_tag="PC512_002071"
     CDS             2002..2826
                     /gene="pstA"
                     /locus_tag="PC512_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003460575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HDF2441813.1"
                     /translation="MRKFKENLLKSLVYLSALFTIVSLVVIVGFIFIKGIGNMNFNFL
                     FSNYSASGDGGILPMIITTLYTVVVSIVVATPIGILAAIYLQEYAKKGKAVTAIRFAT
                     ESLSGIPSIVYGLFGGIFFVVTLKMGYSIVAGSLTVAIIILPVIIRTTEEALKTVPQA
                     YRESSLALGATKFQTLYKVVLPSAIPGILSGVILSVGRIIGESAAILLTAGTVAKMPG
                     GIFDSARTLTVHSYLLTKESGDIATAASIGIVLIVIVLALNMLARFVAKKLNKANY"
     gene            2845..3609
                     /gene="pstB"
                     /locus_tag="PC512_002072"
     CDS             2845..3609
                     /gene="pstB"
                     /locus_tag="PC512_002072"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HDF2441814.1"
                     /translation="MELIDKIKMSVKDLDLFYGDKQALKKINMDIKENKVTALIGPSG
                     CGKSTFIRTLNRMNDLIEDVTIKGNISVDGEDIYTSDDVINLRTKVGMVFQKPNPFPM
                     SIYDNVAYGPRTHGLRDKKQLDKIVEESLKGAAIWDEVKDRLKSSALGLSGGQQQRIC
                     IARAIAMRPEVILMDEPTSALDPISTLKVEELIEDLKKDYTIVIVTHNMQQAARISDE
                     TAFFLNGEVIEFSDTKTMFTTPVDKRTEDYITGRFG"
     gene            3637..4290
                     /gene="phoU"
                     /locus_tag="PC512_002073"
     CDS             3637..4290
                     /gene="phoU"
                     /locus_tag="PC512_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HDF2441815.1"
                     /translation="MVNNSLDISIDTLKEQTVLMMEKCEEAIEKSVTCMIEKDLEGAR
                     KVVEDDEEINKLREEIRDKSIELIVLKQPMARDLRFIYSLGNISIELERIGDYAANIA
                     REMLKIGGEAYIKELIDIPKMAKECKSMMSQTREALILFDASIAYDVGTKDDIVDGLY
                     EQVQIDCLKIMHENSNTIDQGVKLLLIGRYLERIGDHITNVCEKIIFAIEGKMVEIG"
     gene            4448..5317
                     /locus_tag="PC512_002074"
     CDS             4448..5317
                     /locus_tag="PC512_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDF2441816.1"
                     /translation="MKLQKMGMRTIKTGISVTLCMILGDYLVENMFYSLVACIISVQD
                     TVKGSLKTGINRVEGTILGGIIGFIFAIIKAGDPFLCGLGVMCSIYLCNLFKIKSVVV
                     ACVTFLAIHLGVGNSDPVYYSLHRVLDTSVGVLFGVLVNYYVARPNYLNSVIDEFKKI
                     EELSMLLIEDKILRKENLNVEKFEEEVEKLEEIYSKLIDELDYSLSETNIEKIENALR
                     ICREIHFHMQSIELLENKLYLKEHTYKYLKKTYNVDKLDWNIDEEKSPVFNYHLMKIM
                     IEIELLRKLNKSY"
     gene            5404..6840
                     /locus_tag="PC512_002075"
     CDS             5404..6840
                     /locus_tag="PC512_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase"
                     /protein_id="HDF2441817.1"
                     /translation="MNTRNDNSKILEIYKMKLFGELVKAVWNDDIEDIENLPNKILNE
                     DLKDNLNNYFSGKFDKDTMVNLIRVTMGLDVTEDTDKNLKESLHEAVNLDEVKRPIIS
                     VISDACKYCDENNKEDESCKIRSKHINCNEEDVCSACGDCVSRCKLGAISDKIEFIPM
                     IKLLKDIKSPVYAIVAPAFVGQFGKDVSPGKLRTALKKIGFEDMIEVALAADMLTAKE
                     AYDYYEHMKKDEEGCFITSCCCPIWVSLIQNSFPQILENVSPSVSPMIACGRAVKILN
                     PDAKVVFIGPCMAKKKEAMLEDIKDAVDFVLTFKELQEIFDALELNPAIMDESNRVEA
                     SLSGRVYARTGGVSKAVKLSVRRIDKNIKFEEKAFEGTKECMDGLKKVLNKEIEATFI
                     EGMGCVGGCVGGPKRILSVEEGTKNVDEYSESTNMETPFDNLNVLQFLTSLGIKRVES
                     LGEKEEEKVKKIFSRDIKSNKKENKYKK"
     gene            6888..7715
                     /locus_tag="PC512_002076"
     CDS             6888..7715
                     /locus_tag="PC512_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDF2441818.1"
                     /translation="MKIKDNKAVFHVFIRIFLIAVLILTGTLLEEKINNVPVENISSK
                     GENTLELLSQSNTLGEIIYKASQEETKGPGATSEKVAYITIDDGPSKYTNALLDILKE
                     NDVKATFFMLNQNMKNHKEEVRRVLEEENSIGFHSVSHDIHKLYKSPEVTVGEFNTCN
                     NTLQEITGQSSKLIRLPYGSKPYMPEGSYNKLMANDYLIWDWNLDTQDWKSSTSQIVS
                     NILYYGRKRDELVVLIHEKEQSLNALNNIIRILKERGYTILPITENITPKNFWQENL"
     misc_binding    8011..8273
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            8349..11015
                     /locus_tag="PC512_002077"
     CDS             8349..11015
                     /locus_tag="PC512_002077"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HDF2441819.1"
                     /translation="MENTNLSKTYNPKDFEARLYKKWMDEGYFKSKPNPDKKPFTIMM
                     PPPNITGQLHMGHALDHTLQDILIRWKRMDGYEAFWLPGTDHASIATEVKVVERIKKQ
                     EGKTKYEIGREEFLKRAWEWKDEFGGKISNQLKQLGDSCDWDKERFTMDEGCNEAVIE
                     FFVSLYEKGHIYRGNRIINWCPDCKTTLSDAEVEHEEHDGNFYHIKYPLKDSEDFLEI
                     ATTRPETMIGDTGIAVNPEDDRYKHLIGKTAILPLVGRELPIVADSYVDLEFGTGAVK
                     MTPAHDPNDFEVGLRHNLEQLNTMNEDGTMNEVCGKYEGMDRFECRKAIVADLKEQGY
                     LIKIKEHNHNVGTCYRCHTVVEPRLSEQWFVKMEELAKPAIDILKKGELEFVPDKFDK
                     TYLQWLENIRDWCISRQLWWGHQIPAYYCQECGEIVVARKMPDKCPKCGSTHFKQDED
                     ALDTWFSSALWPFSTLGWPNKTEALDYYYPTSVLVTGYDIIFFWVVRMAFAGMFCMNE
                     KPFDHVLVHGLVRDSQGRKMSKSLGNGIDPLEIIEQYGADALRFTLTTGNSPGNDMRF
                     YMERVEFARNFANKLWNASRFVFMNIDEDIIKNMTRESVKEDLTLADKWIISRANNIV
                     KEATNNMDKFDLGIALQKIYDFTWSEYCDWYIEMVKPRLYGEDANAKSAALYTLTYVL
                     EKILKLLHPYMPFITEEIYTHLPTVEGCIIVSEWPKYNEEDNMAEEEDMMNLLMEGIR
                     SIRNVRAEMNVPPSKKAKLIIIPSEEKIEAIELGKDYFITLASASNVEIAKDKSNVPE
                     DAVGVVIDGVEIFIPLNELVDFEKEIERLSKEKKKLEGEIKRVNGKLANQGFLAKAPE
                     SLIEEEKAKKEKFEEMIKSVEERLTNLESKIK"
     gene            11440..12150
                     /gene="rgaR"
                     /locus_tag="PC512_002078"
     CDS             11440..12150
                     /gene="rgaR"
                     /locus_tag="PC512_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RgaR"
                     /protein_id="HDF2441820.1"
                     /translation="MFRVVICDDEKIQRSILKEFTEKLLSERCLNYQILEFSCGEDLI
                     SKYPEKIDIIFLDIQMKDINGIEVAKKIRKFDEKVEIIFTTAFSEYAPQGYEVRAYRY
                     LVKPIEYSNFAMGVNLCIDNLQRKKERYIVLNSKKGFNRILIDSILYVETVKRDLVVH
                     TIGRDYKANMSMKQAEKLLCENGFFRCHTSFIVNLRRIEDLRDNTITINEQFIPISKY
                     RLKDLKVALTSLLCDIMY"
     gene            13196..14227
                     /locus_tag="PC512_002079"
     CDS             13196..14227
                     /locus_tag="PC512_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HDF2441821.1"
                     /translation="MENICDMNNKVKVAVLDTGIDKEHDYLKDNLVGGIAFECMHDYI
                     FISDKFDDEDGHGTACASIIKKEYEDVELFVIKILRKDGITNIKVLEEALRYLLDTNI
                     RLINLSLSVIGVESVKGLFEVCYELFRKGKIIVCSLANDFDLSYPAMFNNVIGVRGFT
                     LDGDDSFWYNKKYDVQCVMDSNSYISCDINNSYRLPPKCNSYLSAKLTGKIAKILSEK
                     PGITISDLNDKLESLATRNHWDSCDFDECSRIVNFKLDLYDKENALFMKVADVVRDCL
                     DIEENNEKLFKGSLFNKEIGLVYDNCFNLLKKLEHRFDIKFNYMDISKYDLVSIYTLT
                     ELVERYKNL"
     gene            14360..15658
                     /locus_tag="PC512_002080"
     CDS             14360..15658
                     /locus_tag="PC512_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HDF2441822.1"
                     /translation="MKYEEALEYISQTNKFGIRLGLENIGKLLELLGNPQETLNIIHV
                     AGTNGKGSVCSFVSNILRECGYKVGLYTSPYLETFTERIRVNGQNIPQDDVARIIELI
                     KEKIEIMVKEGYAYPTEFEVVTAMAFYYYSEQKVDFVALEVGLGGRYDATNIITKSLV
                     SVIVSISLDHTGILGDTIEKIAYEKAGIIKENGVVLVYDQTDEAKDVIKSVCKEKKAK
                     YIEVDFDDINIKKSDINSQIYDCTVMKETYRDLEIKLIGEHQINNSILAISVIKYLKD
                     INKLANINEESIRKGLINTKWPGRIEKIKENPIFIIDGAHNEDGAKSLAKALDKNFKG
                     RKLTLLIGMLEDKDIDSVLEILLPHFNKVITTTPSNPRAINSDILREKVLKYVDDVTS
                     KHEIEDAVNYTLETSSEDDIIISAGSLYMIGTVRTLVKKL"
     gene            complement(15772..16017)
                     /locus_tag="PC512_002081"
     CDS             complement(15772..16017)
                     /locus_tag="PC512_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03905 family TSCPD domain-containing
                     protein"
                     /protein_id="HDF2441823.1"
                     /translation="MKVTFNPSGVCCREMIFEVDENNVIVDAEFIGGCNGNLSGLRSL
                     IIGQNALEVADKLNGIDCGGKGTSCPDQLSKAIRQSI"
     gene            16165..17031
                     /locus_tag="PC512_002082"
     CDS             16165..17031
                     /locus_tag="PC512_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YncE family protein"
                     /protein_id="HDF2441824.1"
                     /translation="MKIYISNYLSKSISIVDYSTLELEKEIVLEDNIYPHHFCIEKEK
                     NLIYIPSSSNGILYVLDLSNDKIIDTVSIGGSLSQVVLSDNELFVANEDSNSIYVLDK
                     NTLNPIGIIGVDNMPHGFDFDRESKKLYVPCINSIVCIDTINKNIQKKINMDFRAWHI
                     ELDKQKKEMYISTLDGKLIIIDEVSMDIKKVLYEFLLPVEIRFNYSGKKVYVADLGYN
                     NVRILDYTTSRYIGNIEINGIPQGLEISKDEKLLFVSDTQENSVKVYETANNKLIKEI
                     KVGKEPTTIICL"
     gene            complement(17035..17571)
                     /locus_tag="PC512_002083"
     CDS             complement(17035..17571)
                     /locus_tag="PC512_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4364 family protein"
                     /protein_id="HDF2441825.1"
                     /translation="MFENSSEELAYHKLLILYILEKIKMDLTNSQITQVVLETEMMNY
                     FSLQQLLSQLMESKFLTTYKDSDREYYALTQRGVESLEYFFNRIPTSVTEKIDKYIDS
                     NKENLLADTQVKSSFVKQSDNEFIVNLRVIENQSNLIDLNLNVSSEKQAKLICNNWKN
                     NASYMYAEVIDLLIRDIH"
     gene            complement(17762..17965)
                     /locus_tag="PC512_002084"
     CDS             complement(17762..17965)
                     /locus_tag="PC512_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta-type small acid-soluble spore
                     protein"
                     /protein_id="HDF2441826.1"
                     /translation="MSNSNRTVVPEAKAALNQMKLEIANEIGLSNYENIDKGNLTARE
                     NGYVGGYMTKKLVEMAERQMAGK"
     gene            18256..19020
                     /locus_tag="PC512_002085"
     CDS             18256..19020
                     /locus_tag="PC512_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDF2441827.1"
                     /translation="MKREVKRTKALIYSVLFFSLLLVLIFVFVYGIKYICSKSDNSKM
                     PIYKVDTNEKKIALSFDVAWGTDNMDDILKILDKHNVKATFFLVGSWVDDNEEIVKAI
                     DEKGHEIGNHSNTHANLKEISKEDITKEIETTSEKIYNITGKRTNLFRPPFGDVNNKA
                     MDICSDLGYKVIKWDVDSIDWKELGPNHVIEKVIKESQPGSIVLFHANINDVDNYLDT
                     IISRLKKDGYSLVKISDLLYKDNYVVDSNGVQKTKN"
     gene            19409..20722
                     /gene="prdC"
                     /locus_tag="PC512_002086"
     CDS             19409..20722
                     /gene="prdC"
                     /locus_tag="PC512_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase-associated electron transfer
                     protein PrdC"
                     /protein_id="HDF2441828.1"
                     /translation="MNKLYSILLKQHVGGPDKPVVSVGDVVKKGTLIAEPTGLGANIY
                     ASVSGKISEINDQAIVIEADEVQEDTFEPLKGEGILDLIKEAGVVGMGGAGFPTHVKL
                     NIDLNGGTILANAAECEPLLAHNIKEIEERPEIVYQGIKYAMEVTNAGKGMLAIKSKH
                     PKAIEAFKKVIKPGDNIEVAELVDMYPMGEERAIVRDVLGKLLEPTQLPSEANAVVIN
                     VETLTRIVEAVEQKRPVISKNITVVGQLNSGKESIVFEDVPIGTTVGELIERAGGIKG
                     EYGEIILGGPFTGKATTLDAPITKTSGGIIVTMPFVNEKRKMGLLVCACGPNEERMRD
                     IATKMGVTDIVSVQKCKQAQEIKGALKCENPGHCPGQAQKCIEFKKAGAEVILIGNCT
                     DCSNTVMGSAPKLKLGVYHITDHVMRTVNHPLIRRIKGDVRLKIK"
     regulatory      21126..21211
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            21793..24042
                     /locus_tag="PC512_002087"
     CDS             21793..24042
                     /locus_tag="PC512_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-Gln thioester bond-forming surface protein"
                     /protein_id="HDF2441829.1"
                     /translation="MKTKIKKSSIISLVIAFSMVFTAFTPIVSYADEVTSNDTILNGE
                     EQSNGQTSDVEKPSDGQVPDGEKPSDSQVPDVEKPSDGQVPDGEKPSDSQVPDGEKPS
                     DGQVPDGEKPSDGQIPDGEKPSDGQIPDGEKPSDGQIPDGEKPSDGQMPDGEKTSDSQ
                     TPDVEKPSDGQMPDGEKPLDEQTPEEEKPLEEEIVIEEMSLKQDIDKILDMTLSQINK
                     IVYNFWEDEEDVKADEQSEINQVFTSEDSFISLWYDKKAKVKNSCLLKEIDGSDRPYH
                     DLRFDDITKTLTFDYVIKGLVGASSKDDKYVIEGEDGEQTAFCYNNHLRPPSSNGKSP
                     YLPAEDFNGQENQNEEAVKSILYAGSEFDGFGYKQQFNLGGEENELMTYSATQSAIWI
                     ILGQMDEQERLKQYQGSINLCDKLIERAKTEEERAEYQKKKEVAINIKAYLEALLKAG
                     REELKPNNTGKPSLSNGLTKINFEKNEDGTYETEAVALVGYSGVVKLKLPDGVTAYDG
                     DGNIIGTGEVEISTQQKFKLKSVGKPDAKANISAVSYDYIFPKAIQYYKAVLDLGQKD
                     HSSSLPSSKQNLLSYTIEKKNGQEVNFNIGLPTDDDDVVNPPVPPIDDDVVNPPVPPT
                     DDTNGHKPKPSPPIDDTVINPPVPPMDDTIINPPVPPTEDAVLNPPVPPMEDAVLNPP
                     VPPTEDTVLNPPVPSVSDTVEKTPELSRDDTIIKSPKTGDETQLMSYVFISVIAICGL
                     AYQCKIKRN"
     gene            24449..26209
                     /gene="prdR"
                     /locus_tag="PC512_002088"
     CDS             24449..26209
                     /gene="prdR"
                     /locus_tag="PC512_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 dependent transcriptional regulator
                     PrdR"
                     /protein_id="HDF2441830.1"
                     /translation="MFSIPEVKKVEEVMDTKFTTIDEDTRIEDAIKEMIKSNTKTLMV
                     IDSSDQLKGIISMTDIHNLYEMHKKYEGQPVKLIMKKDVIYVNEGLTLDECRDIMILK
                     NIGILPVLRDNKIIGVLKQEHIRDYLYMHLEDYGLTLKYIIGQIKEGICAINNEGVVI
                     LWNKFMEERYDIKSEDIVGRPMNEFLENTISEKVLNSKVGMSDLYFTDKKENMYALVH
                     ANPIFYKEEFIGVVCTEVDVTEAKILALELEKVNDTLKYLKNEVKNLSKGSFDKILGK
                     SYKLEKSKAIAKQVARTNSSIFIWGESGTGKEVFARAIHDYSERKGQFIPVNCSAIPN
                     ELFESEFFGYESGAFTGASKKGRIGIFELAKDGTVFLDEIADLPLSMQAKLLRVLQEK
                     EIRRVGGDTTIKINPRIISATNKDLSKMVKAEKFREDLYYRLNVVEIKIPPLRERKED
                     IGLLVHSFLEEICKQNNKPVLTISKDVIDIFQNYRWKGNIRELKNTIENIVVLSQNSK
                     IDVDDVPSYMMDSTNNSTEEEEYPLDLTKATQKIEIKNITKALKMSNGNKAKAAKILN
                     IPRTTLYYKIDQYKIDVSKI"
     gene            26638..28518
                     /gene="prdA"
                     /locus_tag="PC512_002089"
     CDS             26638..28518
                     /gene="prdA"
                     /locus_tag="PC512_002089"
                     /EC_number="1.21.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-proline reductase (dithiol) proprotein PrdA"
                     /protein_id="HDF2441831.1"
                     /translation="MSITLETAQAHANDPAVCCCRFEAGTIIAPENLEDPAIFADLED
                     SGLLTIPENGLTIGQVLGAKLKETLDALSPMTTDNVEGYKAGEAKEEVVEETVEEAAP
                     VSEAAVVPVSTGVAGETVKIHIGEGKNISLEIPLSVAGQAGVAAPVANVAAPVASAAA
                     EVAPKVEEKKLLRSLTKKHFKIDKVEFADETKIEGTTLYIRNAEEICKEANETQELVV
                     DMKLEIITPDKYETYSEAVLDIQPIATKEEGELGSGITRVIDGAVMVLTGTDEDGVQI
                     GEFGSSEGELNTTIMWGRPGAADKGEIFIKGQVTIKAGTNMERPGPLAAHRAFDYVTQ
                     EIREALKKVDNSLVVDEEVIEQYRREGKKKVVVIKEIMGQGAMHDNLILPVEPVGTLG
                     AQPNVDLGNMPVVLSPLEVLDGGIHALTCIGPASKEMSRHYWREPLVIRAMEDEEIDL
                     VGVVFVGSPQVNAEKFYVSKRLGMLVEAMEVDGAVVTTEGFGNNHIDFASHIEQIGMR
                     GIPVVGVSFSAVQGALVVGNKYMTHMVDNNKSKQGIENEILSNNTLAPEDAVRIMAML
                     KNAIEGVEVKAPERKWNPNVKLNNIEAIEKVTGEKIVLEENEQSLPMSKKRREIYEKD
                     EN"
     gene            28599..28883
                     /locus_tag="PC512_002090"
     CDS             28599..28883
                     /locus_tag="PC512_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441832.1"
                     /translation="MDRLKYISSETFYEGIIVDIKGGGVTIDLKGRLGQFKIPNRMLI
                     TDYELKIGQEVGFMLSYPEVLSPEPNQEYVENIRREKEKQAEMQSKQEEK"
     gene            28921..29646
                     /gene="prdB"
                     /locus_tag="PC512_002091"
     CDS             28921..29646
                     /gene="prdB"
                     /locus_tag="PC512_002091"
                     /EC_number="1.21.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:29371..29373,aa:Sec)
                     /transl_table=11
                     /product="D-proline reductase (dithiol) protein PrdB"
                     /protein_id="HDF2441833.1"
                     /translation="MSLTTVQGLQSEIFVPITPPPVWTPVTKELKDMTIALATAAGVH
                     LKSDKRFNLAGDTTFRAIPNTATVDEMMVSHGGYDNGDVNKDINCMFPIDRLHELAAE
                     GFIKGVAPMHYAFMGGGGNQHVFTEETGPAIAAKLKEEGVDGVVMTAGUGTCHRTAVI
                     VQRAIEEAGIPTIIIAALPPVVRQNGTPRAVAPLVPMGANAGEPHNIEMQTHILRDTL
                     EQLVAIPSAGKIVPLPYEYKAHV"
     gene            29726..30484
                     /gene="prdD"
                     /locus_tag="PC512_002092"
     CDS             29726..30484
                     /gene="prdD"
                     /locus_tag="PC512_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase cluster protein PrdD"
                     /protein_id="HDF2441834.1"
                     /translation="MEEKIMRRLVIKPFHMNEVNFGSKTSIKKDVLTIDLSSIDEIKE
                     REELITDIKVDIIKPGDYDREINTIMDIIPISTKVLGRLGEGITHTLTGVYVMLTGAD
                     EDGNQMHEFGSSEGILKDQMVFGRYGTPSVEDYIIHVDVTLKGGLPFERTLPLAAFRA
                     CDDFIQEIRASLKMEDGRNATQVREYFDKIRPNAKKVVIVKQIAGQGAMYDNQLFSKE
                     PSGFEGGTSIIDMGNVPMIISPNEYRDGALRAMT"
     gene            30499..30966
                     /locus_tag="PC512_002093"
     CDS             30499..30966
                     /locus_tag="PC512_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase"
                     /protein_id="HDF2441835.1"
                     /translation="MGIGPSTKETSLHHFRDPLLDIVESDKDVDLLGVIVVGTPDGNE
                     NKTFVGQRTAAWLEAMRVDGAIVSSDGWGNSHVDYANTFEEIGKRDIPVVGVTFNGTQ
                     AKFVVSNQYMDTIVDMNKSKEGIETEVVGENNTNEIDAKKALAFLKLKMRKHG"
     gene            30984..31466
                     /locus_tag="PC512_002094"
                     /pseudo
     CDS             30984..31466
                     /locus_tag="PC512_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428088.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase"
     gene            31486..32493
                     /locus_tag="PC512_002095"
     CDS             31486..32493
                     /locus_tag="PC512_002095"
                     /EC_number="5.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline racemase"
                     /protein_id="HDF2441836.1"
                     /translation="MKFSRSIQAIDSHTAGEATRIVVGGIPNIKGNSMPEKKEYLEEN
                     LDYLRTAIMLEPRGHNDMFGSVMTQPCCPDADFGIIFMDGGGYLNMCGHGTIGAMTAA
                     IETGVVPAVEPVTHVVMEAPAGIIRGDVTVVDGKAKEVSFLNVPAFLYKEGVEVDLPG
                     VGTVKFDISFGGSFFAIIHASQLGLKIEPQNAGKLTELAMKLRDIINEKIEIQHPTLA
                     HIKTVDLVEIYDEPTHPEATYKNVVIFGQGQVDRSPCGTGTSAKLATLHAKGELKVGE
                     KFVYESILGTLFKGEIVEETKVADFNAVVPKITGSAYITGFNHFVIDEEDPLKHGFIL
                     K"
     gene            32613..33494
                     /locus_tag="PC512_002096"
     CDS             32613..33494
                     /locus_tag="PC512_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HDF2441837.1"
                     /translation="MVAILKALYVVFAAIFAVVFGKDVAKANKEGKLEEQSTPKVAVT
                     GFITDFFDTLGIGSFAPTIAMSKALKLNIPDKKMPGTLNVAHTIPVVTEAFIFTSIIP
                     VDGVTLVSMVVAAAVGSYIGAGIIAKMDERKIQLVMGVTLALTAILMLLGHPWINVLP
                     GGGNELGLTGVKLVIGVIGNFILGALMTAGIGLYAPGMAMVYFLGMSAKVAFPIVMGS
                     CALLMPVASMKFIKEDAYTKKASVIIAICGLIGVFVAAYIVKTLPMDILKALVIVVIA
                     YTSATMIMAANKNKKTA"
BASE COUNT        13427 a         3752 c         6195 g        10398 t
ORIGIN      
        1 aaatagttaa ataataagat taagaatttc ttaataaatc cagaagatgc tttcgattat
       61 ataatatttt atatttttat attattaatt atatgtgttg caatcgctgc acctactttt
      121 tctggtgagt atcagacaca atcagatagc atccttcgtt gtacgaaaca tggacatatt
      181 cgtctagcgt ttactaaaat attagctcta ttttctatat ttataataat gtttgttata
      241 tgtatttcta tccatttggc aatttctgat ttagcttttg gtactgaatg tttgaaaacc
      301 tcatttcaaa tgttgttttc tgtcattagt ctagtaaata taaatttact acaagcacag
      361 attcttatag ctattggtgg tctaatttca atacttgcaa tggttagttt aacattattt
      421 ttatctgcaa aatgtaagga ttctcttact tctatgctga ttgctttttc tatttgctta
      481 attcctatgg gaataggtgt tagttggatt ggatacctat taccaccagg gggaattggt
      541 tttaagatta gtttattata tcaaatgaca tcatttaatt tcttacactt aggaggtatg
      601 agtttttgga caccacacat tatactgttt ttctcagtga tagaaatacc tatttttata
      661 tttttggcta ttcgtaccta ttgcaaacat caagtaccgt aacaatttga tggaaataat
      721 agtgatataa actagaggat acaataatta tatatgtagt ataaaagtta aatttagtta
      781 acaaatctta atagcagata taggtaataa attatacata aactgtatta ttatctatat
      841 ctgctatttt aatatagaga aacaacagta tattgtaaag taaatgtcaa atatagtttt
      901 aaaagtaaaa ttaatgttaa aaagtaaata taattttaca cttgcttaac ttaatcctaa
      961 tatagattta acttaaaaaa agtagaataa aagtatagga aatttgatga agacgaatta
     1021 taaaaaatta aattttgaat acagaacgaa aatcgataag tatattttaa tgggagggta
     1081 ttatgatagt aaaatctaga ttagtaggtt tagaaaaaaa tgacaataat ggcaataaga
     1141 caaaatacgt aattgaaaaa gtagcaaaaa atatttttct acttagtgct ttagtagcag
     1201 ttgcaagttt acttttgata ataggattcg tattttataa aggattaaga ccatttatat
     1261 ttgaaggata ttcatttata gactttttaa ctggtgcaga ttgggttcct tctgccaata
     1321 aatttggaat atcatctatg atagtagcat caatatttgc aacacttgga gcacttgtta
     1381 taggagtacc tgttggtata ttaacctctg tatttatagc agaagtagca cctaaaagat
     1441 tagcaaaaat aatgtcacca gcagttgaac ttttagcagg tataccttca gtattatatg
     1501 gtgtatttgg tcttgcagtg atagttccaa ctatacaagg tatatttaat cttccaaaag
     1561 gtcaaagttt gttagcaata gtaatagtat tagcagtaat gatgttacca acaataatat
     1621 ctgtatcaga aacagcaata agagcagtac caaaagcata caaagaaggt tcattagcac
     1681 ttggtgcatc aaaaatagaa acaatattca aagttgtatt acctgctgca aaatctggag
     1741 tattagccgc agtagtgtta ggagtaggaa gagctttagg tgaaacaatg gcagtaatac
     1801 ttgttgcagg caactcacca gttatgccaa ctgcaataac agatagtgta agaccactta
     1861 caactaatat agcacttgaa atgggatacg catttggtac acatcaagaa atgctatttg
     1921 caactggagt agtattgttt acatttatat taattttaaa cttagtttta aataaacttt
     1981 caaataaggc ggtaaattaa gatgagaaag ttcaaagaga atctattgaa gtcattagta
     2041 tatctatcag cactatttac aatagtatca ttagtagtta tagtgggatt tatatttata
     2101 aagggaattg gcaacatgaa ttttaatttc ttatttagca attattcagc atcaggtgat
     2161 ggtggtatac ttccaatgat aattacaaca ttatatacag tagtagtttc tatagttgta
     2221 gcaactccta taggaatatt ggctgctata tatttacaag aatatgctaa aaaaggaaaa
     2281 gcagttacag ctataagatt tgcaactgaa agtttatcag ggataccatc tatagtatat
     2341 ggattatttg gaggaatttt ctttgtagtt acattaaaaa tgggatattc catagttgca
     2401 ggttcactta cagttgcaat aataatatta ccagtaataa ttcgtacaac agaagaagct
     2461 ttaaaaacag ttcctcaagc ttatagagaa tcatcattgg cattaggagc tacaaaattt
     2521 caaactttat ataaggtagt acttccaagt gcaataccag gaattttatc tggagtaatc
     2581 ttatcagttg gtcgtataat tggagaatca gctgcaatat tacttacagc aggtactgta
     2641 gccaagatgc caggtggaat atttgatagt gcaagaacat taactgtaca ctcatactta
     2701 ctgactaaag agagtggaga tatagcaaca gcagccagta taggaattgt tttaatagta
     2761 attgtattag cactaaacat gctagcaaga tttgttgcta agaaattaaa taaagctaat
     2821 tattaaattt aagaggtgtg aataatggaa ttaatcgata agataaaaat gagtgtaaaa
     2881 gatttggatt tattttatgg tgataagcaa gcattaaaga aaataaatat ggatataaaa
     2941 gagaataagg ttactgcttt aataggtcca tctggatgcg gaaaatcaac ttttataaga
     3001 acgttaaata gaatgaatga cttaatcgaa gatgtaacaa ttaaaggaaa catttctgtt
     3061 gatggagagg acatatatac ctcagatgat gttataaatc ttcgtactaa agtaggaatg
     3121 gtatttcaaa agccaaatcc atttcctatg agtatatatg ataatgtggc atatggtcct
     3181 cgtacacatg gactaagaga taagaagcaa ttagataaaa ttgtagaaga aagcttaaaa
     3241 ggtgcagcta tttgggatga ggttaaagac aggcttaaat catctgcact aggactttct
     3301 ggtggtcaac aacagcgtat atgtatagca agagcaattg ctatgagacc agaagttatt
     3361 cttatggatg aacctacatc tgctttagac ccaatttcaa cattaaaagt agaggaactt
     3421 atagaggatt taaaaaaaga ctacacaata gtcatagtta cacataatat gcaacaagct
     3481 gctcgtatat cagatgaaac agcttttttc ttaaatggag aggttataga atttagcgat
     3541 acaaaaacta tgtttaccac tcctgtagat aaaagaacag aagactatat aacaggtaga
     3601 tttggttaaa atatataact ataaaggagt tagacaatgg tcaataatag tttagatata
     3661 agtattgata ctttaaaaga acaaacagtg cttatgatgg aaaaatgtga agaagcaata
     3721 gaaaagtctg tgacttgtat gatagagaag gatttagagg gtgcaagaaa agtagtagaa
     3781 gatgatgaag aaataaataa attaagagaa gaaataagag ataagagtat agagctaata
     3841 gtattaaagc aaccaatggc aagggactta agatttattt attcattagg taatatatct
     3901 atagagctgg aaagaatagg agattatgca gcaaatatag ctagagaaat gttgaagata
     3961 ggtggagagg cttatataaa agagctaata gatattccta agatggcaaa agaatgtaag
     4021 tctatgatgt ctcagactag agaagcttta atcttatttg atgcaagtat agcttatgat
     4081 gttggaacta aagatgatat tgtagatgga ttgtatgaac aagtacaaat tgattgttta
     4141 aaaataatgc atgaaaactc aaataccata gaccaagggg taaaacttct acttatagga
     4201 agataccttg aaagaattgg agaccatata acaaatgtat gtgagaagat aatttttgca
     4261 attgagggta aaatggttga gataggataa aaaactgctt taaagcagtt tttttattgt
     4321 ctaaattaag aaagaattga taaaaaaata tgattaatgg gtaaatttaa aaaattgtga
     4381 tatactagga acatattaaa tatgaggatg cgtattttat ataaggtgct ttttaggagg
     4441 tggaactttg aaacttcaaa agatgggtat gaggactata aaaacaggaa ttagtgtcac
     4501 tttatgtatg attcttggtg actatttagt agagaatatg ttttattctc tggtagcatg
     4561 tataatttct gttcaagata cagtaaaagg ttctttaaag acgggaatca atagagtgga
     4621 aggtactatt ttaggtggta taataggatt catatttgca atcattaaag ctggagaccc
     4681 atttttatgt ggtctaggag taatgtgctc aatatattta tgcaatctgt ttaaaataaa
     4741 gtcagtagta gttgcctgtg taacctttct ggctatacat ctaggtgtag gaaatagtga
     4801 ccctgtgtat tattctttac atagggtgtt agatacatct gtgggtgttt tgtttggagt
     4861 acttgttaat tattatgttg ctagaccaaa ttatctaaat agtgttatag atgagtttaa
     4921 aaagatagaa gaactttcaa tgttgcttat tgaagataaa attcttagaa aagaaaattt
     4981 aaatgtagag aaatttgaag aagaagtaga aaaattagaa gaaatatatt caaaacttat
     5041 tgatgagttg gattatagtt tgagtgaaac taatatagaa aaaattgaga atgccttaag
     5101 gatatgtaga gaaatacatt ttcatatgca gtctatagag ttacttgaaa ataaacttta
     5161 tttgaaagag catacatata aataccttaa gaaaacatat aatgtggata agctagactg
     5221 gaatatagat gaagaaaaaa gccctgtatt caactatcat ctaatgaaaa taatgattga
     5281 aatagagttg ttgagaaagc taaataaatc atattaataa tagtagttaa ataataaata
     5341 aaaaatagta tctttgtaaa tattaaacat atataagttt aatttatgga ggtactattt
     5401 tttatgaata ctagaaatga caattctaaa atactagaaa tatataaaat gaagcttttt
     5461 ggcgaacttg taaaagcagt gtggaatgat gatatagagg atattgaaaa cttacctaat
     5521 aaaattttaa atgaagattt aaaggataat ttaaataatt attttagtgg aaaatttgat
     5581 aaagatacta tggtaaattt aattagggta actatgggat tggatgttac agaagataca
     5641 gataaaaatt taaaagagtc actgcatgaa gctgtaaatt tagatgaagt caaaagacca
     5701 ataatatctg taatatcaga tgcttgcaaa tattgtgatg aaaataataa ggaagatgag
     5761 tcatgtaaga taagaagtaa gcatattaat tgtaatgagg aagatgtatg tagtgcttgt
     5821 ggtgattgtg tatcaagatg taagttgggt gcaatttcag ataaaataga atttatacca
     5881 atgataaaat tgttaaaaga tataaagagc cctgtatatg caatagttgc accagctttt
     5941 gtaggacagt ttgggaaaga tgtaagccct ggtaaattaa gaactgcatt aaaaaagata
     6001 ggatttgaag atatgataga agttgctttg gcagcagata tgcttactgc aaaagaagca
     6061 tatgattatt atgagcatat gaaaaaggac gaagaaggat gctttataac tagttgttgc
     6121 tgtcctattt gggttagttt gatacaaaat agttttcctc agatattgga aaatgtatca
     6181 ccatccgttt ctcctatgat tgcttgtggg agagctgtaa aaattttaaa tccagatgct
     6241 aaagttgtat tcataggtcc ttgtatggca aaaaagaaag aagcaatgtt agaagatata
     6301 aaagatgcag ttgattttgt gcttacattt aaagagttgc aagaaatatt tgatgcatta
     6361 gagttaaatc cagcaataat ggatgagagt aatagagtag aggcgtccct ttcaggtaga
     6421 gtttatgcta gaacaggagg tgtaagtaaa gcagttaagt tatcagttag aagaattgac
     6481 aaaaatataa aatttgaaga aaaggcattt gaaggaacaa aagagtgcat ggacggtcta
     6541 aagaaagttc taaataaaga aatagaagct acatttatag aaggaatggg gtgtgtagga
     6601 ggctgtgtag gaggtccgaa gcgtatttta agtgtggaag aaggtactaa gaatgttgat
     6661 gaatatagtg aaagtacgaa tatggaaact ccatttgata atttaaatgt attacaattt
     6721 ttaacttctt tgggaatcaa aagagtagaa tctttaggag aaaaagaaga agaaaaggtt
     6781 aaaaaaatat ttagtagaga tataaaaagt aataagaaag agaataaata taaaaaataa
     6841 ctttttaagt cttaaactta tgcttttata aaagggagat atgggggatg aaaattaaag
     6901 ataataaggc tgtttttcat gtatttataa ggatatttct tatagctgtt ttaattttaa
     6961 ctggaacatt attggaggaa aaaattaata atgttccagt tgaaaatata agttcaaaag
     7021 gtgaaaatac actggaactg ctttctcaaa gtaatacttt aggagaaatc atatacaaag
     7081 catctcaaga agaaacaaaa ggtccagggg ctacttctga aaaagtagca tacataacaa
     7141 tagatgatgg tccatcaaaa tatacaaatg cactacttga tattttaaaa gaaaatgatg
     7201 tcaaagcgac atttttcatg cttaatcaga atatgaaaaa ccacaaggaa gaagtaagga
     7261 gagtcttgga agaagaaaac tcaataggtt ttcatagtgt aagtcatgat atacataagt
     7321 tatataaaag cccagaagta acagttgggg aatttaatac atgcaataat actctacaag
     7381 aaataactgg tcagagttca aaattaataa gattaccata cggaagtaaa ccatatatgc
     7441 cagaaggttc atataataaa cttatggcaa atgattattt aatttgggac tggaatttgg
     7501 atacacagga ttggaagtct tctacaagtc agatagtaag taatatatta tattatggaa
     7561 gaaaaagaga tgaattagta gtattaattc atgagaaaga gcaaagttta aatgctttaa
     7621 ataatattat aagaatctta aaagagagag gatatacaat attgccaatt acagaaaata
     7681 taacacctaa aaatttctgg caagaaaact tataataaat ttaaatatag taaaagataa
     7741 agtaaattat ttataaaata aaacatataa tataaaaaat acgaataaga ggtatactgt
     7801 aaggataata taaaattaat gagaaagcat taaaattaaa ataaaataat cttgcaatta
     7861 ttgacattat aagacagaat aactgtaaaa acatatttta aaatataaca actatataaa
     7921 agagaataga cataattaag aaaattcaga aaaaataaaa taaaaataat tgacaaagag
     7981 aataatattt gtatataata atatgtaata ttaaagactg agaagaagag gagtaagtaa
     8041 atactactaa aagagaggaa aattcactgg ctgtaagatt ttctaagtat aagatttact
     8101 gaatgtagct ttggagtttc taaactgaac tataagtaag tttagacggt tagaaccgtt
     8161 aaattctttg agagtcaaag ttgataaaat aacattaacc aataatttaa ttatatgtta
     8221 atgtatttta agctttggaa ttaaggtggt aacgcgagct tttcgtcctt tttaaagagg
     8281 atgaagagct cttttttatt tctaaagata tttaaaaaat ttatttataa aatacaggag
     8341 gcaggacaat ggaaaatacg aatttatcaa aaacttataa cccaaaagat tttgaggcta
     8401 ggctatataa aaaatggatg gatgaagggt attttaaatc taaaccaaat ccagataaaa
     8461 aaccatttac aataatgatg ccaccaccaa atataacagg gcaattgcat atgggacacg
     8521 ctcttgacca tacacttcaa gatatattaa tcagatggaa acgtatggat ggatatgaag
     8581 ctttttggct tccaggaact gaccatgctt ctatagcaac agaagttaaa gttgttgaaa
     8641 gaataaaaaa acaagaaggc aagacaaagt atgaaatagg tagagaagaa tttttaaaga
     8701 gagcctggga atggaaagat gaatttggag gaaaaatatc taatcagctt aaacaactag
     8761 gtgattcttg tgattgggat aaagaaagat ttactatgga tgaagggtgt aatgaagcag
     8821 ttatagaatt ttttgtaagc ctatatgaaa aaggtcacat atacagagga aatagaataa
     8881 taaactggtg cccagattgc aaaactactt tatcagatgc agaagttgaa catgaagaac
     8941 acgacggaaa cttttatcat ataaagtacc cactaaaaga tagtgaagac tttttagaaa
     9001 tagctacaac tagacctgag acaatgatag gagatactgg tatagcagta aatccagaag
     9061 atgatagata taaacattta ataggaaaaa cagcaatact tccattagta ggaagagaac
     9121 ttccaatagt tgcagatagt tatgttgatt tagagtttgg aactggtgca gttaagatga
     9181 ctccagcaca tgaccctaat gattttgaag taggattaag acataatctt gagcagttaa
     9241 atactatgaa tgaagatgga actatgaatg aagtttgtgg aaaatatgaa ggtatggata
     9301 gatttgagtg tagaaaagct atcgtagcag acttaaaaga acaaggttac ctaattaaga
     9361 taaaagagca taatcataat gtaggaactt gttatagatg ccatacagta gttgagccta
     9421 gattatcaga gcaatggttt gttaagatgg aagaacttgc aaaaccagct atagatattc
     9481 ttaaaaaagg agaattagaa tttgttccag ataaatttga taaaacttat ttacaatggc
     9541 tagaaaatat aagagattgg tgtatatcaa gacaattatg gtggggtcat caaataccag
     9601 cttattattg tcaagagtgt ggagaaatag tagttgctag aaaaatgcca gataagtgtc
     9661 ctaaatgtgg aagcactcat tttaaacaag atgaagatgc cttagatact tggttcagtt
     9721 ctgcattatg gcctttctct actctaggat ggccaaataa gactgaagct ttagattatt
     9781 attatccaac aagtgtactt gttacaggat acgatataat attcttctgg gtagttagaa
     9841 tggcatttgc aggtatgttc tgtatgaatg aaaagccatt tgaccatgtt ttggttcatg
     9901 gattagtaag agattctcaa ggtagaaaaa tgagtaaatc tttaggaaat ggtatcgacc
     9961 cattggagat aatcgagcaa tatggagctg atgccctaag atttacatta acaactggaa
    10021 attccccagg aaatgatatg agattctata tggaaagagt agaatttgct agaaactttg
    10081 caaataagtt gtggaatgca tcaagatttg tatttatgaa tattgatgaa gatataatta
    10141 aaaacatgac tagagaaagt gttaaagagg acttaactct agctgataaa tggataatat
    10201 caagagcaaa taatattgta aaagaagcaa ctaataacat ggataagttt gatttaggaa
    10261 tagcacttca aaagatatac gattttactt ggtcagaata ctgtgactgg tatattgaaa
    10321 tggttaaacc tagattatat ggggaagatg caaatgctaa atctgcagca ttatatacat
    10381 taacttatgt tcttgaaaag atattaaaat tattacatcc atatatgcca tttataacag
    10441 aggaaatata tactcatctt cctactgttg aaggatgtat aatagtatct gaatggccaa
    10501 aatataatga agaagataac atggctgaag aagaagatat gatgaactta ttgatggaag
    10561 gtataagaag tataagaaat gtgagagcag aaatgaatgt accaccttct aagaaagcta
    10621 aattgataat aatcccaagt gaagaaaaaa tagaagctat tgagcttggt aaagactatt
    10681 ttataacttt agcatctgct tcaaatgtag agatagcaaa agataaatct aatgttccag
    10741 aagatgcagt tggagtagtt attgatggtg ttgaaatatt tatacctctt aatgaattag
    10801 ttgattttga aaaagaaatt gagagattat ctaaagaaaa gaaaaagtta gaaggcgaaa
    10861 taaagagagt taatggaaag cttgcaaatc aaggtttctt agcaaaagct cctgaaagtt
    10921 taattgaaga agaaaaagca aaaaaagaaa aatttgaaga gatgattaaa tctgttgagg
    10981 aaagattaac aaatttagaa tctaaaataa aataaatata agaattagta aaaacataca
    11041 aaaagtatat attctatact ttttgtatgt ttttctttat atatatacaa atatgatgtt
    11101 ataattcttt acagatgtgt tatattttta ttttatgttg tgaatatatg aattttatgt
    11161 cttaaaattt ataagcaata aaaatttgat atattatgat gtttaatata gggtaataaa
    11221 tacatattat atttatttta ctatattttt ttacataata tatctagaaa agtataggaa
    11281 tttatcgtaa tttaagttta aatattaaag agaatttcta taagtagttt aatcgacaat
    11341 ttaaatttat aaagaaattt aaatttgaaa gctagtgagt acagtttgga aattgaaata
    11401 aagtaaacta aatgatattt tagatttgga ggtgatatta tgttcagggt agttatatgt
    11461 gatgacgaaa aaatacaaag aagcatacta aaagagttta cagaaaaact tttgtctgaa
    11521 agatgtctaa attatcaaat actggaattt tcctgtggag aagatttaat atccaaatac
    11581 ccagaaaaaa ttgatattat atttttagat atccaaatga aagatatcaa tggaattgag
    11641 gtggctaaaa aaataagaaa gtttgatgaa aaagtagaaa ttatatttac aacggctttt
    11701 tcagagtatg ccccccaagg ttatgaagtt cgtgcttata gatatttagt aaagcctata
    11761 gagtatagta actttgcaat gggtgtaaat ctttgtattg ataaccttca aagaaagaag
    11821 gagcgttata tagttttaaa tagtaaaaaa ggatttaata gaatactgat agattctatt
    11881 ttatatgttg aaactgtaaa gagagattta gttgtacata caataggtag agattataaa
    11941 gctaatatga gcatgaaaca agcagaaaaa ttactgtgtg aaaatggctt ttttagatgt
    12001 catacaagtt ttattgttaa tttaagaaga atagaagatc ttagggataa tacgattact
    12061 attaatgaac aatttatacc tataagtaag tatagactta aagatttaaa agtagcatta
    12121 acaagcttgt tatgtgatat aatgtattaa ttttaaaaag gtaattgaaa atatcgtaaa
    12181 aaagatttaa tgtcatcaca gggctattga ttgaaactgt cttaatatat aaaatgttat
    12241 ttatattaag acagttttat tatgcaaaat agcagtttat agacttttaa tatggtttaa
    12301 tatgtatatg tagagtttcc attataatag catgattatt aattagtagc ttgattatca
    12361 atatactatt attgattttt atatgtatta tatgtatttt tagaatatga ttaccttttt
    12421 aaaataatga ctatttataa aactctatag atatttgttt catttagcta tgcatacttt
    12481 aattaattat attaatattt aatggagtac aatataaata ttaaagcgac atcttatagt
    12541 ttattgaacc tatagtaatg aattaataaa tagtttaatt ctatgaaaag atttcctttt
    12601 atgcaattta tttattgaaa tatgatataa tatataaagg tgtaagtatt agttgttaaa
    12661 ataatattta tattagtttt tatgcatact tggtataagt ttttcatata ttgattaaaa
    12721 ttgatgttga tttattattt ttagtatttt ttcacctttt gattcatact ttgtagaatg
    12781 gtgtattttc taaaactgat tataagacaa gttcattcaa attagcattt ttatatcata
    12841 taaataattg ttccccctaa ataagattta gatgtatagt attaaaatca aaaagtataa
    12901 aataaaattg atgcttaatc atagataaat attaataaaa tatacaaggg gattgtctaa
    12961 taaaaagata atctcctttt ttacaaataa ttctaaattg tgatataaat ctaaaaattt
    13021 tatcttaaca tttaaccatt taatgataat aattgatata ataaatataa attaaatata
    13081 tggtgtactt attttatgtt tttagcaaga aatatagcat ttaaaagata aattgtgcaa
    13141 cttaaatcaa agtttaagat gaactattaa catagatata ttaaaaactt ttgtaatgga
    13201 gaatatatgt gatatgaata ataaagttaa ggttgcagta ttagatacag gaatagacaa
    13261 agaacatgat tacttaaaag ataatttagt tggaggaatt gcttttgaat gtatgcatga
    13321 ttatatcttt atatcagata aatttgatga tgaagatggt catggaactg cttgtgcatc
    13381 aataataaag aaagagtatg aagatgtaga gttatttgta ataaaaattt tgagaaaaga
    13441 tggtattaca aatataaaag ttcttgaaga agcattaaga taccttttag acactaacat
    13501 aagattaatt aatttaagtt tatcagtcat aggagtagaa agtgttaagg gcttatttga
    13561 agtttgttat gaattgttta gaaaaggaaa aataatagta tgttcactcg ctaatgattt
    13621 tgacttaagt tatccagcta tgtttaacaa tgttataggt gtaagaggat ttactttaga
    13681 tggagatgat tcattttggt acaacaaaaa atatgatgtt caatgtgtta tggatagcaa
    13741 ttcatatata agttgtgata taaataattc ctatagatta ccaccaaaat gtaatagtta
    13801 tttatcagca aagcttactg gtaaaatagc taagatatta tcagaaaaac caggcataac
    13861 aatatctgat ttaaatgata agcttgaatc attagcaact agaaatcatt gggatagttg
    13921 tgattttgat gagtgtagta gaattgtaaa ctttaaattg gatttgtatg acaaagaaaa
    13981 tgctcttttt atgaaagttg ctgacgttgt tagggattgc ttagatattg aagagaataa
    14041 tgaaaaactc tttaagggta gcctttttaa taaggagata ggcttggttt atgataattg
    14101 ttttaatctg ttgaaaaagc tagagcatag atttgacata aagtttaatt atatggacat
    14161 ctcaaaatat gacttagttt caatatatac actgactgaa ttagtggaaa gatataaaaa
    14221 cttataaata aagatttgta gctaaattta atgtagaagg tattaaatta tatgtattct
    14281 ttgtcggtag attaaaagta aaaaatatac tataattaga tagcataaga gaaaatgcca
    14341 atacaggggg agttagataa tgaaatatga agaagcatta gagtacatat cacaaactaa
    14401 taaattcggt ataagattag gattagaaaa tatcggaaag ttattagaat tattaggaaa
    14461 tccacaagaa actttgaata taatacatgt agctggaact aatggaaaag gttctgtgtg
    14521 ttcttttgtt tctaatatac taagagagtg tggatataaa gttggtttat atacatctcc
    14581 atatttagaa acttttactg agcgtataag agtaaatgga caaaatatac cacaggatga
    14641 tgttgctaga ataattgagt taataaaaga aaaaatagag attatggtaa aagaaggcta
    14701 tgcatatcca acagaatttg aagtggttac tgcaatggca ttttattact attcagaaca
    14761 aaaggtagac tttgtggcat tagaagttgg tttaggtggc agatatgatg ctacaaatat
    14821 aataacaaaa tcacttgtaa gtgtgatagt atctataagt ttggaccata caggtatact
    14881 tggagataca atagaaaaaa tagcgtacga aaaggctgga ataataaagg aaaatggagt
    14941 agtactagta tatgaccaga ctgatgaagc aaaggatgtt ataaagtcag tttgtaaaga
    15001 gaaaaaagct aaatatatag aagttgattt tgatgatata aacataaaaa aatcagatat
    15061 aaattctcaa atatacgatt gtactgtaat gaaagaaact tatagagacc ttgaaataaa
    15121 attgataggc gaacatcaaa taaacaattc tatcttggca attagtgtaa taaaatatct
    15181 aaaagacata aataaattag caaatataaa tgaagaatct ataagaaaag gacttataaa
    15241 tactaaatgg ccaggaagaa tagaaaagat aaaagaaaat ccaattttta taatagatgg
    15301 tgcacataat gaagatggag caaaatcttt ggcaaaagca cttgataaga attttaaagg
    15361 tagaaaatta accttattaa taggtatgtt agaagataaa gatattgata gtgttttaga
    15421 gatattgttg ccacatttta ataaggtaat aacaacaaca ccaagtaacc caagagccat
    15481 aaattcagat atattaagag aaaaagtatt aaaatatgta gatgatgtaa catcaaagca
    15541 tgagatagag gatgcagtaa attatacatt agaaacatca agtgaggatg atattataat
    15601 aagtgcaggt tcattatata tgattggtac agtgagaact ttagtaaaga aattataatt
    15661 ttataaaata agtatacaaa taaaaatata aaaaagagtt gtctaaaaaa tggacaactc
    15721 tttttatata aaataagttt ttaataattt tactgatgtt tatataagta attatataga
    15781 ttgacgtata gctttagata attggtctgg gcaagaagta ccttttccac cacagtcaat
    15841 accatttaat ttatcagcaa cttcaagagc attttggcca attattaagc ttctaagtcc
    15901 tgataaatta ccattacatc ctcctataaa ttcagcatca acaatcacat tattttcatc
    15961 aacttcaaaa atcatttctc tacaacatac accacttgga ttaaatgtta ctttcattaa
    16021 aaagacctcc attaaatatt atttcttttt ttaacattaa taataatacc aaatatatgc
    16081 gtaataatgc aactataaag cataatacaa gctaatgaaa taatatatta ttgtagtata
    16141 tgtattgtag agaggagggg ttatatgaaa atctatattt ctaactactt atcaaagagt
    16201 attagcatag ttgattattc tacacttgaa ctagaaaaag aaatagtatt agaagataat
    16261 atatatccac accatttttg catagaaaaa gaaaaaaatt taatatacat acctagttca
    16321 agtaatggga tactctatgt cttagattta agtaatgata aaataattga tactgtctct
    16381 ataggaggaa gtcttagtca agttgtactt agcgataatg aattgtttgt ggcaaatgaa
    16441 gattctaata gtatatatgt actagataaa aacacattaa atccaatagg aattattgga
    16501 gttgataata tgccacatgg atttgacttt gatagagaaa gcaaaaagtt atatgtaccg
    16561 tgtataaact cgatagtatg tatagataca attaataaaa atatacaaaa gaaaataaat
    16621 atggacttta gagcttggca tatagaactt gataaacaaa agaaagaaat gtatatatca
    16681 acacttgatg gaaagcttat aataatagat gaagtaagca tggatataaa aaaggtatta
    16741 tatgaatttt tattaccagt agaaataaga tttaattata gtggcaaaaa agtttatgtt
    16801 gctgatttgg gttataataa tgtaagaatt ttagattata caacgagtag atacattgga
    16861 aatattgaaa taaatgggat tccccaagga ttagaaatat ctaaagatga aaagttacta
    16921 tttgtatcag atacacaaga aaattcagta aaagtttatg aaactgcaaa taacaaatta
    16981 ataaaagaaa tcaaggtagg aaaagagcct acaactataa tttgtttgta ggctttaatg
    17041 tatgtctctt ataagtaaat cgataacttc ggcatacata taagatgcat tatttttcca
    17101 gttattgcaa ataagttttg cttgtttctc tgatgaaaca tttagattta aatctattaa
    17161 gttagactga ttttctatga ctctaaggtt gacaataaat tcattatcac tttgttttac
    17221 aaaactagac tttacttgag tatctgctag tagattttct ttgttagaat ctatatactt
    17281 gtctattttt tcagtaacac tagtaggtat tcgattaaag aagtattcta gactttctac
    17341 gcctctttga gtaagagcat aatattctct gtcagagtct ttatatgtag tcaaaaactt
    17401 agattccata agctgagata aaagctgttg taatgaaaaa taattcatca tctcagtctc
    17461 taatactact tgagttattt gagaattagt taaatccatt ttaatttttt ctaatatata
    17521 taaaattaaa agtttgtgat aggctaattc ttcagacgag ttttcaaaca taaatatcat
    17581 cctccgtcaa actatttcta tatataatat attaaactaa tttgtacaaa attaaaagaa
    17641 caatttgtat tgtattatta atctttaata attcatataa aaacaatttt ataaataaat
    17701 atagaaaaac agggctgcta attagcagcc ctgttgatac ccaggtgtca aaatttacta
    17761 tttattttcc agccatttgt ctttcagcca tttcaactaa tttcttagtc atatatccac
    17821 caacatatcc attttctcta gctgttaagt tacctttgtc tatgttttca tagttagata
    17881 aacctatttc gttagctatt tctaatttca tttggtttaa agcagctttt gcttctggaa
    17941 ctactgttct gtttgaattt gacatagtaa atttcctcct caaataatta gtttatgatg
    18001 tctaacaaca cttttattta tgtgatgtta atactaattt ctccaaaata aaaataatat
    18061 atacagaaaa ataaaggtaa aaatgtaaaa aatataaaaa aattaaataa atgagtattt
    18121 tagagagttt aattaggtca atataggttt tattttttta gttattgtct tataaattaa
    18181 atattacagt acttttttga gctgaaaaaa aataaatttt aaatatagaa gaaattattt
    18241 caaaggggga atagtatgaa aagagaagtt aaaaggacta aagctttgat atatagtgtt
    18301 ttattttttt cattattatt agtgttaata tttgtttttg tttatggaat aaaatacata
    18361 tgttctaaat ctgacaattc aaaaatgcct atatataaag ttgatacaaa tgagaaaaaa
    18421 atagctttga gttttgatgt agcatgggga actgataata tggatgatat tttaaaaatt
    18481 ttagataaac ataatgtaaa agcgaccttc tttttagttg gtagttgggt ggatgataat
    18541 gaagaaattg taaaagctat agatgaaaaa ggacatgaaa ttggaaatca ttcaaatact
    18601 catgccaatt taaaggaaat atcaaaagaa gacataacaa aagagataga aactacatca
    18661 gaaaaaatat ataatataac aggaaaaagg actaatttat ttagacctcc ttttggggac
    18721 gtaaacaata aagctatgga catttgtagt gatttaggtt ataaagtaat taagtgggat
    18781 gtagattcta tagactggaa ggagcttgga ccaaatcatg taattgaaaa agtaataaaa
    18841 gaatctcaac ctggttcaat agttttattc catgctaata taaatgatgt agataattat
    18901 ttggatacta taataagtcg actaaaaaaa gatggataca gtctagtcaa aatatctgat
    18961 ttgttgtata aagataatta tgtagttgat tccaatggag tgcaaaaaac taagaattaa
    19021 taagtaataa atgtatattt taagtaaagt tgtgataaat tatatagtat atgttagaaa
    19081 agtgtcgata aaaagacggt gtctattttt tgacactttt tatacatgta tgcaatatca
    19141 ataattatag attaaattga ttaaaaaagt gtctaataat tgactttttt ttgatgggtt
    19201 taaaaattta gaagaattaa tgaatgctgt aagacagtat ttccaaaggg tataagtttg
    19261 tttaaaagtt ggcatagaaa ttgctttgtt aataagcgat atgttctata gaaataaaca
    19321 atatgttaag accttataat agaaaaatag cattaacatt atttgaacag cttataaaaa
    19381 aattaatata cttaaggggg cgtactagtt gaacaaacta tattctattt tattaaaaca
    19441 acacgttggt ggtccagata agccagtagt aagtgttgga gatgtagtaa aaaaaggaac
    19501 tctaatcgca gaaccaactg gattaggggc aaatatttat gccagtgtta gtggaaaaat
    19561 aagtgaaata aatgaccaag cgatagtaat tgaagctgat gaagtacaag aagatacttt
    19621 tgaaccatta aaaggagaag gtatacttga cttaattaaa gaagctggag tagtaggaat
    19681 gggtggagca ggattcccta ctcatgtaaa attaaacata gatttaaatg gtggaacaat
    19741 attagcaaat gcagctgaat gtgaaccttt attagctcat aatataaaag aaatagaaga
    19801 aagaccagaa atagtttatc aaggtataaa atatgctatg gaagttacta atgctggaaa
    19861 aggtatgcta gcaataaaaa gtaagcatcc aaaagcaata gaagctttca aaaaagtaat
    19921 aaagccagga gacaacatag aagttgcaga actagttgat atgtacccaa tgggagaaga
    19981 gagagcaata gtaagagatg ttctaggaaa attacttgag ccaactcaat taccttcaga
    20041 ggctaatgca gtagtaataa acgtagaaac actaactaga atagtagagg ctgttgagca
    20101 aaaaagacca gttatatcta aaaatataac tgtagttggt caattaaaca gtggaaaaga
    20161 atctatagtg tttgaagatg tgccaattgg aacaactgtc ggagaattaa ttgaaagagc
    20221 tggtggaata aaaggtgaat atggtgaaat aatcctagga ggacctttca ctggtaaagc
    20281 tactacttta gatgctccaa taactaaaac tagtggtggt ataatagtta ctatgccatt
    20341 tgttaatgaa aagagaaaaa tgggtctttt agtttgtgca tgtggaccta atgaagaaag
    20401 aatgagagat atagcaacta aaatgggagt tactgatata gtatcagttc aaaaatgtaa
    20461 acaagctcaa gaaattaaag gtgcattaaa atgtgaaaat ccaggacact gtccaggaca
    20521 agctcaaaaa tgtattgaat ttaagaaagc tggagcagaa gttatattaa taggaaactg
    20581 tactgactgt agtaacacag taatgggttc tgcaccaaaa ttaaaattag gtgtatatca
    20641 tattactgac catgtaatga gaacagttaa tcacccatta ataagaagaa taaaaggtga
    20701 cgtaagatta aaaataaaat aatagataaa tagaagttag acatctttag aagtaaaact
    20761 taaaagttac ttctaaggat gttttttaat gtattttgag ggcaatatat atattgtaaa
    20821 ataaatggaa aaaatagaca aaatatgcta gatattgtat aatgataaca atagctatta
    20881 caattaatat tggacaaaaa taatgatact caagtatgtg gtttgtatta atatgcatat
    20941 tatattaagt caactatccg atagagtaaa aggtttttgt gatatttgaa gatactctat
    21001 agtatctttt ttattataaa aactaatttt tgtcttttat tagataagta tctaggatac
    21061 taatttatat tttattgagt tgttaaaaaa gtgcacttaa aaagttaaaa aagaaaaatt
    21121 aaaaacctat ttatagaaac tgtgaagtat atcttaaacc tgggcactta aaagatatat
    21181 ggagttagta gtgcaacctg ctataaatat aaataggagt aacttttaat tgtcaaaaat
    21241 atataaaata aatacataaa taagtaatta atagaagata gatataaata tatttttgaa
    21301 atgctccctg cattcataac gagtgtagag tggcagatat ctgcccaaaa ctcctttaat
    21361 tgctggaagt tcctaaagct aactaaacca caacataatc atgaaataag gataagtgtg
    21421 atagagtgtg catttaataa gcacttgagg ttacgaaagt agaaaaaatt agttagatag
    21481 cataaggtta aatcctaagt gccttgaaaa tggataatca gcaggtaagc ttcgaaaaga
    21541 agaaacttca acgactagag agaaatctcg tacctacaag tgtggggaaa tggggagtac
    21601 ctaatttatg gttaggtaat gatatagtct gtgcttaata gaaatattaa gaagttcata
    21661 ggagaactgg ttaggagtaa cgaccctaat tgaacacact aaagatgtat tattgaataa
    21721 gattcatata atatttaata attttaatta tattaagtga atacaatata tgtttttagt
    21781 atcaggagaa ttttgaaaac aaaaattaaa aaatcaagta taatcagttt agtaattgct
    21841 tttagtatgg tatttactgc atttacacca atagtatctt atgctgacga agtgactagc
    21901 aatgatacaa tacttaatgg agaagaacaa tcaaatggtc agacatcaga tgtagagaaa
    21961 ccatcagacg gtcaggtacc agatggggag aaaccatcag acagtcaagt accagatgta
    22021 gagaaaccat cagacggtca ggtaccagat ggggagaaac catcagacag tcaagtacca
    22081 gatggggaga aaccatcaga cggtcaggta ccagatgggg agaaaccatc agatggtcag
    22141 ataccagatg gggagaaacc atcagatggt cagataccag atggagagaa accatcagat
    22201 ggtcagatac cagatgggga gaaaccatca gatggtcaga tgccagatgg agagaagaca
    22261 tcagatagtc agacgccaga tgtagagaaa ccatcagatg gtcagatgcc agatggggag
    22321 aaaccattag atgagcaaac tccagaagaa gaaaaaccat tggaagaaga aatagttata
    22381 gaggaaatga gtttaaaaca agatattgat aaaattcttg atatgacttt atctcaaata
    22441 aataaaatag tatataactt ttgggaagat gaagaagatg taaaggcaga tgaacaatca
    22501 gaaattaacc aagtttttac ttcagaagac tcatttatta gcttatggta tgacaaaaaa
    22561 gcaaaagtaa aaaattcttg tttactaaaa gaaatagatg gttcagatag accttatcat
    22621 gatttaagat ttgatgatat tacaaagact ttaacttttg actatgtaat aaagggtctt
    22681 gtaggagcaa gctcaaaaga cgacaaatat gtaatagaag gtgaagatgg agagcaaact
    22741 gcattttgtt acaataatca tttaagacca ccaagtagta atggaaagag tccatattta
    22801 ccagcagaag attttaatgg tcaagaaaac caaaatgaag aagcagttaa atctatacta
    22861 tatgcaggtt ctgaatttga tggatttgga tataagcaac aatttaattt aggtggagaa
    22921 gaaaatgaat tgatgactta ctcagctact caaagtgcaa tttggattat tcttggacaa
    22981 atggatgaac aagaaagact taagcagtat caaggttcta taaacctttg tgataaactt
    23041 atagaaagag caaaaactga agaggaaaga gctgagtatc agaagaagaa agaagtagcg
    23101 ataaatataa aagcttattt agaagcattg ttaaaagcag gtcgtgaaga gttaaagcca
    23161 aataatacag gaaaacctag tttgagtaat ggtttaacta agattaactt tgaaaaaaat
    23221 gaagatggta cttatgaaac agaagctgta gccttagtag gttatagtgg tgtagtaaag
    23281 ttaaaactac cagatggagt aactgcttat gatggagatg gtaatataat aggtacaggc
    23341 gaagtagaaa tttcaacgca acagaaattt aaacttaaga gtgttggaaa accagatgcc
    23401 aaagctaata tttctgctgt atcttatgat tatatttttc caaaagctat tcaatattat
    23461 aaggcagtgc ttgatttagg acaaaaagac cattcatctt cattaccatc tagcaagcaa
    23521 aatttattaa gttatacaat agagaaaaag aatggtcaag aagttaactt taatataggt
    23581 ttaccaacag atgatgatga tgttgtaaat ccaccagtgc caccaataga tgatgatgtt
    23641 gtaaatccac cggtgccacc aacagatgat acaaatggac ataagccaaa accatcacca
    23701 ccaatagatg atacagtaat aaatccacca gtaccaccaa tggatgatac aataataaat
    23761 ccaccagtac caccaacgga ggatgcagtg ttaaatccac cagtgccacc aatggaggat
    23821 gcagtgctaa atccaccagt gccaccaaca gaggatacag tgttaaatcc accagtacca
    23881 tcagtaagtg atacagtgga aaaaactcca gaactatcaa gagatgatac aataataaaa
    23941 tcaccaaaaa caggtgatga aactcagcta atgtcatatg tatttattag tgtcattgca
    24001 atttgtggat tagcgtatca atgtaaaata aaaagaaatt aatctagatt attattaagt
    24061 ttaaaataaa aagtctcaaa ttgatttata agtcattttg gggctttttt atgtaaatat
    24121 aatatgcaaa tatagtttgt ttaaaaatat ctattttaat tatattctta aatttattat
    24181 tggatacagg cattcattaa ttgtttgatg aatagaaaaa tgttttgaag gtgaaaatag
    24241 tattgaaaaa ataatatact aagggtataa ttcatttgat ttcatttgta taaatttaat
    24301 tataaatttt aaagtgatta tataaattta aatgctaatt acttaataaa ttttaataat
    24361 aattatttaa taaataatta ttataatatg ctagaataaa tatatataaa taagttttga
    24421 tgaggtacta ctataaaggg gggactttat gttttcgata ccagaagtaa aaaaagtaga
    24481 agaggtaatg gatacaaaat ttacaactat agacgaagac acaagaattg aagatgcaat
    24541 aaaagaaatg ataaaaagca acacaaaaac tctaatggta atagattcat ctgaccaatt
    24601 aaaaggcatt atatccatga cggatataca taatctttat gagatgcata aaaagtatga
    24661 aggtcaacca gtaaaactta taatgaagaa ggatgtaata tatgtcaacg aaggtttaac
    24721 cttagatgaa tgtagagata taatgatatt aaaaaatata gggattcttc ctgttcttag
    24781 agataataaa attattggag ttctaaaaca agagcacatt agggactatc tatatatgca
    24841 tttagaagat tatggattaa ctttgaagta tattataggt caaattaaag aaggaatttg
    24901 tgctataaat aacgaaggtg ttgttatctt gtggaataag tttatggagg aaaggtatga
    24961 tataaagtct gaagatatag ttggtcgacc gatgaatgaa tttttggaaa atactatttc
    25021 agaaaaagta ctaaatagta aagttggaat gagtgacttg tattttacag ataaaaaaga
    25081 aaatatgtat gcattagttc atgcaaatcc tatattttat aaagaagaat ttatcggtgt
    25141 tgtatgtaca gaagttgatg ttacagaagc taagatatta gctcttgaac ttgaaaaagt
    25201 aaatgataca ttaaaatatc taaagaacga agtcaaaaat ttatctaaag gtagttttga
    25261 taagatttta ggtaaaagtt ataaattgga aaaatcgaaa gcgattgcaa aacaagtggc
    25321 tagaacaaat agtagtatat ttatttgggg cgaaagtggt acaggtaaag aagtatttgc
    25381 aagagctatt catgattata gtgagagaaa agggcaattt atacctgtta actgtagtgc
    25441 cataccaaat gagttatttg aaagtgagtt ttttgggtat gaatcaggtg catttacagg
    25501 agcaagtaaa aagggtcgaa taggtatatt tgaacttgca aaagatggaa ctgtattttt
    25561 agatgaaatt gccgatttac ctcttagtat gcaagcaaag ttgcttagag tattacagga
    25621 aaaagaaata agaagagttg gtggagatac cacaataaaa ataaatccta gaataatatc
    25681 agctaccaat aaagatttga gtaaaatggt aaaggcagaa aaatttagag aagatttata
    25741 ctatagatta aatgttgttg aaataaagat tcctccactt agagagagaa aagaagacat
    25801 aggattattg gttcatagct ttttagagga gatatgtaaa caaaataata agcctgttct
    25861 tacaattagc aaagatgtaa tagatatatt tcagaattat agatggaaag gtaatattag
    25921 agaattaaaa aatacgattg aaaatattgt tgtattgtca caaaattcta aaatagatgt
    25981 ggatgatgta ccaagttata tgatggattc tacaaataat agtactgaag aagaagagta
    26041 tcctttagat ttaacgaagg caactcaaaa aattgaaata aagaatataa ccaaggcact
    26101 taaaatgtct aatggaaata aagctaaagc agctaagata ttaaatatac ccagaacaac
    26161 tttgtattat aagatagacc aatacaaaat agatgtgtct aaaatatgac acatgactaa
    26221 attttgacaa aatgataaac tttaatttaa aacctagtaa agccaacact tgtataagtg
    26281 ttgtgtatat agatgtgtta aaaaaaatga aaaagtgttg attaattgac actttttttg
    26341 tttgagaaaa tgtttacaaa tacaaaaaat aacatatttt aaataaatat ttatataata
    26401 tttggctaaa aatagcgata gatgaagaat ctattataga aaaaatcttt ttgttaataa
    26461 gttggcatag gaattgctta taatataaag tgactttaag tgagaaaaaa ataatattaa
    26521 tcataacaaa ttatgtaggt tttaatttac ttaatttctc agttaagggg ttacctgttg
    26581 aggaattgag atttaaaata ataaataaga aaataatgta aggaggtatt ttatactatg
    26641 tcaataactt tagaaacagc tcaagcccat gcaaatgacc cagcagtttg ttgttgtaga
    26701 tttgaagcgg gaacaattat agcgccagaa aacttagaag atccagcaat atttgcagac
    26761 ttagaggatt ctggattatt aacaatacca gaaaatggat taactatagg tcaagtacta
    26821 ggagctaagt taaaagaaac tttagatgca ctttctccaa tgactacaga taacgtagaa
    26881 ggatacaaag caggagaggc taaagaagaa gtagtagaag aaacagtaga agaagcagct
    26941 ccagtatcag aagcagcagt agttccagta agcacaggag ttgcaggtga aacagttaaa
    27001 atacacatag gtgaaggtaa gaacataagc ttagagatac ctttatcagt agctggtcaa
    27061 gcaggagttg ctgctccagt agcaaacgtt gctgctccag tggcaagtgc agcagcagaa
    27121 gtagctccaa aagttgaaga aaagaaactt ttaagaagct taactaaaaa acactttaaa
    27181 atagataaag ttgaatttgc tgatgaaact aaaatagaag gaactacttt atacatcaga
    27241 aacgcagaag aaatatgtaa agaagctaat gaaactcaag agttagttgt agatatgaag
    27301 ttagaaataa taactcctga taaatatgaa acttacagtg aagctgtatt agatatacaa
    27361 ccaatcgcta ctaaagaaga aggcgaatta ggttcaggta taactagagt tatagatgga
    27421 gctgtaatgg tattaactgg tacagatgaa gatggagttc aaataggtga atttggttct
    27481 tcagaaggtg agttaaatac tactataatg tggggtagac caggtgctgc tgacaaaggt
    27541 gaaatattca tcaaaggtca agtaacaata aaagcaggaa ctaacatgga aagaccagga
    27601 cctttagctg ctcaccgtgc atttgactat gtaactcaag aaataagaga agcattaaag
    27661 aaagttgaca actctttagt agttgatgaa gaagtaatag agcaatacag aagagaaggt
    27721 aaaaagaaag ttgttgttat aaaagaaata atgggacaag gtgcaatgca tgataaccta
    27781 atattaccag ttgagccagt tggtacatta ggagctcaac caaacgttga cttaggaaac
    27841 atgccagttg tattatctcc acttgaagta ttagatggtg gtatccatgc attaacttgt
    27901 ataggacctg catcaaaaga aatgtcaaga cattactgga gagagccatt agtaataaga
    27961 gctatggaag acgaagaaat agatttagta ggtgttgtat ttgttggttc tccacaagta
    28021 aatgctgaga aattctatgt atctaagaga ttaggtatgt tagttgaagc tatggaagtt
    28081 gatggagctg tagtaactac tgaaggtttc ggaaacaacc atatagattt cgcatctcac
    28141 atagagcaaa taggtatgag aggtatacca gtagttggtg taagtttctc agctgttcaa
    28201 ggtgctctag ttgttggtaa taaatacatg actcacatgg tagacaacaa taagtctaag
    28261 caaggtatag agaatgaaat attatctaac aacactttag ctccagaaga tgctgttaga
    28321 ataatggcta tgcttaaaaa tgctatagaa ggtgtagaag ttaaagctcc tgaaagaaaa
    28381 tggaatccaa atgttaaatt aaataacata gaagctatag aaaaagttac aggagaaaaa
    28441 atagtattag aagagaatga gcaatctcta ccaatgagta agaagagaag agaaatatac
    28501 gaaaaagacg aaaactaaaa tttagatact aactaagatt tagacaataa cataaattta
    28561 gatccaagtt taaaacagta tagagaggta gaattataat ggataggtta aaatatatct
    28621 catcagagac tttttatgaa ggtattatag ttgacatcaa aggcggtgga gtgactatag
    28681 acctaaaagg tagacttgga caatttaaaa tacctaatag aatgcttata actgactacg
    28741 aacttaagat aggtcaagaa gttggattca tgctaagcta tcctgaggta ttaagtccag
    28801 agcctaatca agagtatgta gaaaatatta ggagagaaaa agaaaaacaa gcagaaatgc
    28861 aatcaaaaca agaagaaaaa taataaataa tcgtttgaaa atagaaggga gaggaaatat
    28921 atgagcctta caacagtaca aggacttcaa tctgaaatat tcgttccaat aacacctcct
    28981 ccagtttgga ctcctgtaac taaagaatta aaagatatga ctatagcttt agctacagca
    29041 gctggtgttc atttaaaatc tgacaagaga tttaatctag caggagatac tacatttaga
    29101 gctataccta atacagctac agttgatgaa atgatggtat cacatggtgg atatgacaat
    29161 ggagatgtaa acaaagatat aaactgtatg ttccctatag atagattaca tgaattagct
    29221 gcagaaggat ttatcaaagg agtagctcct atgcactatg cattcatggg tggtggagga
    29281 aaccaacatg tcttcactga agaaactggt cctgctatcg ctgctaaact taaggaagag
    29341 ggagtagacg gtgtagttat gacagctggc tgaggtactt gccatagaac tgccgtgatc
    29401 gtgcagagag caatagagga agctggaata cctacaataa taatagcagc tcttcctcca
    29461 gtagttagac aaaacggaac tcctagagca gttgctccat tagttccaat gggtgctaat
    29521 gctggtgaac cacataatat agaaatgcaa acacatatat taagagatac attagagcaa
    29581 ttagttgcaa taccatctgc tggtaagata gttccattac catacgaata taaagctcac
    29641 gtttaaaatg taatttatat ttgaaaatat agaacccttc tcctacacgg ttaggagagg
    29701 ggttttaaga acaaaggtgg atattatgga agaaaaaata atgagaagac ttgttataaa
    29761 accgtttcat atgaatgaag ttaatttcgg ttcaaaaact tctataaaga aagatgtact
    29821 tacaatagat ttatcaagta tagatgaaat aaaagaaaga gaagagttaa taacagacat
    29881 aaaagtagac attataaaac ctggagatta tgacagagaa attaatacta ttatggacat
    29941 tataccaata tcaacaaaag ttttaggcag actgggagag ggtattacac atactttaac
    30001 gggtgtatat gtaatgttaa ctggtgcaga tgaagatgga aatcaaatgc atgaatttgg
    30061 ttcttcagaa ggaattttga aagaccaaat ggtatttggg agatatggaa ctccatcagt
    30121 tgaagattat ataatccatg tagatgtaac tttaaaggga ggtttacctt ttgaaagaac
    30181 acttccactt gcagcattca gagcatgtga tgattttata caagaaataa gagcgtcttt
    30241 gaaaatggaa gacggaagaa atgctactca agttcgtgaa tattttgaca aaattcgacc
    30301 aaatgcaaaa aaggttgtca tagtaaaaca aatagcaggt caaggtgcta tgtatgacaa
    30361 tcagttattc tcaaaggaac ctagtggatt tgaaggagga acatcaatta tagatatggg
    30421 aaatgtacct atgattatat ctcctaatga atacagagat ggtgccctta gagctatgac
    30481 ttaagagagg tggatattat gggaatagga ccttcaacaa aagaaacatc tcttcatcac
    30541 tttagagacc cacttttaga catagttgaa agtgataagg atgtagattt acttggagta
    30601 atagtagtag gaactccaga tggaaatgaa aataaaacct ttgtgggaca aagaacggcc
    30661 gcttggctgg aagccatgag agtagatgga gctatagttt catcagatgg ttggggaaac
    30721 tcacatgttg actacgctaa cacatttgag gaaataggaa aaagagatat acctgtagtt
    30781 ggagttacat ttaatgggac tcaagctaag tttgttgtaa gcaatcaata tatggatacc
    30841 atagttgata tgaacaaatc aaaagaaggt attgagacag aagtagttgg agaaaacaac
    30901 acaaatgaaa tagatgctaa aaaagctttg gcatttttaa aacttaaaat gagaaaacat
    30961 ggataaaaaa tttaagtaag ggaatgagtt ttgtgggaat ttctacatca atgaaaaaca
    31021 catcacttca tatatttaga gacccgttac tagatttgat agataatgat tctgacatag
    31081 acttgttagg agtggttgta gttgggacat cagagcacaa tgaatggaaa acatttttag
    31141 caactagact tggaagatgg attgaatcat tgcgacctga tggagtgatt ataactttag
    31201 atatggcagg aaaccagcac attgatttta caaatgctat agcagagttt gtaaaatcag
    31261 atatacctac agtaggtctt actattatgg gagcagatgg attagtaatt accaatccat
    31321 agttggataa agctaccata attgattata aaaagacaac aggctacata gaaacagaag
    31381 tagttggaga caatcacatg gatgaagttg atgttaaaaa agcattggct ttcctaaaat
    31441 taaaaatgcg taaagacgca aaataaacct aagggggaat ttgatatgaa atttagcaga
    31501 agtatacaag ctatagactc tcatacagca ggtgaagcaa ctagaatagt tgtaggtgga
    31561 atacctaaca taaaaggaaa ttctatgcct gagaaaaaag aatatttaga ggaaaatcta
    31621 gattatttaa gaactgctat aatgttagag ccaagaggac ataatgatat gtttggttct
    31681 gtaatgactc aaccttgttg cccagatgct gactttggaa taatcttcat ggatggtggc
    31741 ggatacctta acatgtgtgg ccatggtaca ataggagcta tgacagcagc tatagaaaca
    31801 ggtgtagttc cagcagtaga gcctgtaact catgtagtta tggaagctcc agcaggaata
    31861 ataagaggag acgttacagt tgtagatgga aaagctaaag aagtatcatt cttaaacgta
    31921 ccagctttct tatataaaga aggtgttgaa gttgacttac caggtgttgg aactgttaaa
    31981 tttgacatat catttggtgg aagcttcttt gctataatac atgcaagtca attaggttta
    32041 aaaatcgaac ctcaaaatgc tggtaaatta actgaactag ctatgaaact tagagatata
    32101 ataaatgaga aaatagaaat acaacatcca actttagctc atataaaaac tgtagactta
    32161 gttgaaatat atgatgagcc aactcatcca gaagctactt acaaaaatgt agttatattt
    32221 ggtcaaggtc aagttgacag atctccatgt ggaactggaa caagtgctaa attagctact
    32281 ttacatgcta aaggtgaatt aaaagtagga gaaaaattcg tatatgaaag tatattagga
    32341 actttattca aaggtgaaat agttgaagaa actaaagttg cagatttcaa tgctgtagta
    32401 cctaaaataa ctggttctgc ttatataact ggatttaatc attttgtaat agatgaagaa
    32461 gacccactta aacatggatt tattcttaaa taagtaataa ataaattagg aaattaaaat
    32521 agaatagtag ccacttgtcg gttgctattc tatagctttt aggctataag attcagaata
    32581 tatgaaaaaa taaaaaaata ggaggatgga ttatggtagc aatcttaaag gcattatatg
    32641 tagtattcgc agcaatcttt gcagttgtgt ttggtaaaga cgtagctaaa gcaaacaaag
    32701 aggggaaact agaagaacaa agtactccaa aagttgctgt aacaggattt ataacagact
    32761 tctttgatac attaggaata gggtcatttg ctccaacaat agcaatgtca aaggctttaa
    32821 agttaaatat accagataaa aaaatgcctg gtacattaaa cgtagcacat actattccag
    32881 ttgttacaga agcattcata tttacatcaa tcataccagt tgatggtgtt actttagtat
    32941 ctatggttgt ggcagcagca gttggttcat atataggtgc aggaataata gctaagatgg
    33001 acgagagaaa aatacaactt gttatgggtg taactttagc attaacagca atattaatgt
    33061 tattaggtca tccttggatt aacgtattac caggtggagg aaatgaatta ggtcttactg
    33121 gtgttaaatt agtaataggt gtaataggta actttatact aggagcttta atgacagctg
    33181 gtataggttt atatgctcca ggtatggcaa tggtttattt cttaggaatg tctgcaaaag
    33241 ttgcattccc aatagttatg ggttcttgtg cattattaat gccagttgca agtatgaaat
    33301 tcataaaaga agatgcatat actaaaaaag catcagttat aatagctata tgtggtttaa
    33361 taggagtttt cgtagctgca tatatagtaa aaactctacc aatggatata ttaaaagcat
    33421 tagtaatagt agttatagct tatacttctg ctacaatgat aatggctgca aataaaaaca
    33481 aaaagactgc ttagttaaag actacttagt gtttattaaa tattacagct aataataaag
    33541 attataaact gctttaaaat attgaattaa tattttaggg cagtttttta tttactaaat
    33601 taatataaag caattaacat gccaattatg taatatatat agtgatttag tagatttaat
    33661 gtaaaaaacg ttgtattttt aaagaataaa gcataattta aagctaaata tttaaatttt
    33721 ataatcaata agttcaataa atgttcatat attaatacag attaataaaa at
//
LOCUS       DAMJVG010000041        33396 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.041, whole genome shotgun sequence.
ACCESSION   DAMJVG010000041 DAMJVG010000000
VERSION     DAMJVG010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 33396)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33396)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33396
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.041"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            177..833
                     /locus_tag="PC512_002097"
     CDS             177..833
                     /locus_tag="PC512_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441838.1"
                     /translation="MKKGDFIWSGVLICIIAVLAIPSSREVFMEATGAHPYIGGFLKF
                     AVLATMGDLLGARILYKDWKIPVGVFYRAIVWGIIGVVTTYGMSIYSSGVGQAQVDGM
                     LPFEGIAFANALFKSATMNILMSPTVFLFHKVMDCFIDKKYEVGKGIKVKLKDVVNIV
                     DWNAYLGFSVLKTIPFFWIPCHTIVFLFPAEYRVIASAFASIALGLILALANKSKVAV
                     "
     gene            complement(1341..2612)
                     /gene="sleC"
                     /locus_tag="PC512_002098"
     CDS             complement(1341..2612)
                     /gene="sleC"
                     /locus_tag="PC512_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore cortex-lytic protein SleC"
                     /protein_id="HDF2441839.1"
                     /translation="MQDGFLTVSIIDATNNRPIQNAVVNIYSMSNGSQSSSTLYQNLR
                     SNESGQVTGLVLPAPDVDYSLQPSDVRPYSQYIVEAIADGYETVVIEGTQLLATIEAR
                     QGVPMSPRTRSKRSFSRQSELIFDIGEHTLYGTYPPKIPESNLKPLPPPTGFVVLDNP
                     VVPEFIVVHDGLPEDSSAPNYWIPFKEYIKNIASSEIYSTWPEQTIYANVIAIISFTL
                     NRVFTEWYRNKGYNFTITSTTAYDHKFINNRNLFEPINVVVDAIFNTFIKRPPTSRQP
                     LLAQYCDGQKSQCPDQMTQWGSKDLGDQGYDYESILRYFYGDEIVFERAPIVSGVPVS
                     FPGTTLQVGSSGQYVRTIQNQLNAISNSYPAVPKVIEDGIYGTDTENAVKIFQGIFGL
                     PQSGVVDFKTWYEISRVYVATTRIASLNPLI"
     gene            2857..3573
                     /locus_tag="PC512_002099"
     CDS             2857..3573
                     /locus_tag="PC512_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HDF2441840.1"
                     /translation="MKLDLFLLAIVPILIGMFWIRSKDRYCREPLIHLIKFFLIGAFL
                     SVIIILLENLLMKFNVFEGYSELIYVSFVVAGLVEEGVKALILIPALIKEKHFTEKLD
                     GIIYSVFLALGFATIENMVYIFSESRNLALQVGINRAVISIPAHVMFAITMGYYISKY
                     KFEGNKNKRREYLFMAVLIPILLHGVFDFILMIEYRWAIILLIVYVIILWKINLDKLE
                     KYMNHSKKVFFGNLRKKKKK"
     gene            3652..4962
                     /locus_tag="PC512_002100"
     CDS             3652..4962
                     /locus_tag="PC512_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HDF2441841.1"
                     /translation="MTELPNEFLEDIEEILKDEYDDFIKSYEESKTTGLRINTLKIDK
                     KKLFDLELFDLNQIPWAEEGFYYDDKIDRPGRNPLHEAGAYYLQEPSAMSVIPKADIK
                     EGEKVLDMCAAPGGKSTYILSKLNDTGLLVSNEINASRIKALGENLERFGARNCIITN
                     TDSNSLRKTFNGYFDKVIIDAPCSGQGMFRKDEVAISDWSYAKVVECQSIQKEIIRDG
                     YKMLKKDGILIYSTCTFSREENEHVINEFISEYPHAELIEMERLWPHKIKGEGHFVAK
                     IKKLEEEECNVKELKIKNLDKEIKDYREFEKKFLKVDFYSNKKNKFYLRGENLYLLPE
                     IYPDTKKLKVLRYGLHLGVLKKNRFEPSHALSHYLKVEDVKNVENFSVQSESILKYLK
                     GDVVNSNDSRGWVLVSVEGIPLGWGKESSGVIKNHYPKGLRKVF"
     gene            5062..5598
                     /gene="lepB"
                     /locus_tag="PC512_002101"
     CDS             5062..5598
                     /gene="lepB"
                     /locus_tag="PC512_002101"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HDF2441842.1"
                     /translation="MGEAVKKEVVEWIKVIVIALVLAFAITRFIVPTIVKGESMYPTL
                     VERDYLIVNRIAYKVGEPKYKDIIVFKTDLTEENGKKKDLVKRVIGVPGDHVKIQDSK
                     VYVNDKLLDETSYIHNNRTDGDIDIVVPEGKLFAMGDNREKSLDSRYDEVGLVDEHTI
                     LGKVLVRLYPFSKIGTID"
     gene            5764..6300
                     /gene="lepB"
                     /locus_tag="PC512_002102"
     CDS             5764..6300
                     /gene="lepB"
                     /locus_tag="PC512_002102"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HDF2441843.1"
                     /translation="MNETIKEEIVEWIKIIITALFFAFIITRFIKPTLVNGESMYPTL
                     KSHDYLVANRMTYKLSEPKCGDIMIFKTDLLQENGRKKELVKRVIGVPGDHLKIKDSK
                     VYINGKLLNEVSYIHDNYTEGDIDMVIPKGKVFAMGDNREVSLDSRYKEVGLVDEENI
                     KGKVILRVFPFTDIGIFE"
     gene            6310..7065
                     /locus_tag="PC512_002103"
     CDS             6310..7065
                     /locus_tag="PC512_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM barrel protein"
                     /protein_id="HDF2441844.1"
                     /translation="MAVGIASLLFNIEEALNICESIKQITHLEIGIDNISECSELCKY
                     KERISKLGLSIGIHLPMELNTCENIEYIRNSWINFIEKIEFELKGFDLRYFNLHLGYV
                     MTNRVRKNRDKYLGNSVDFLDKLNTNSYVCIENTYSKGGDFSNIGNISYDFEYIFKRI
                     KNSKICFCYDTGHCLIDEDAYVKNLKDKIRLIHLSDNDGINDTHVGIGRGILSEEGIK
                     EVLTLDAEYLVLEINYEDIEDTISKLNNIVGEG"
     gene            7139..8806
                     /locus_tag="PC512_002104"
     CDS             7139..8806
                     /locus_tag="PC512_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside kinase"
                     /protein_id="HDF2441845.1"
                     /translation="MKKINLKIEGKDKEYSLEENSPGIRLGDIAKEFCDEHKGYITLA
                     VVDNKLKELNCRVKKDCEINFLDTTNEDGERVYFRVMSFIFVMACREIFWDSRVTIEH
                     SLSDGLYCEVHIDRKLKEADVENIKNKMKEIVNNDYVIEKIEVTRNEAISIFENNEMY
                     EKAELLKYKEYDSAKVYKCRNYIDHFYGYMLPSTGYIKSFDIKLYNGGVIILGPSEED
                     KTLPMKFVPQPKLSSVYYEAEEWSRLMGIDKVVSLNKIIENNEYGDIIRTFEALHEKK
                     LSQIADMIKDGNKRVVLIAAPSSSGKTSFAHRLSIHLRVNNLNPISISLDDYFIDRKH
                     TPLDEYGNYDFESIYAIDLEKFNLDLKKLLAGEEIDDIRFNFKEGKREYTGKKIKIDS
                     NQPIILEGIHGLNPILTSSIPDEDKFKIYISALTQINLDDHNRIPTADLRMIRRIVRD
                     YNFRGYSADNTILQWASVRRGEKKNIFPYQEEADAIFNSACVYELAVLKRFAKPLLEE
                     IKEDNPAHIEATRLLKFLQYFVELDDTSDIPGISILREFIGGSKIVD"
     gene            9339..10268
                     /gene="glsA"
                     /locus_tag="PC512_002105"
     CDS             9339..10268
                     /gene="glsA"
                     /locus_tag="PC512_002105"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HDF2441846.1"
                     /translation="MNTLDETLLKEIISSNKKYTNYGQVASYIPELKNARRNDLGICI
                     IDSENNLYSAGNCSTKFTIQSISKPIVLAMALMDNDWEDVFSNVGMEPSGDPFNSIMK
                     LEINDTKKPCNPMINAGAIVTTSLINGSCLEEKEERMLSFFRKLAKNDNIGINYDVYK
                     SEKMTGDRNRAMAYLLKSDGFIRGNVEDVLDLYFKQCSIEIDSVDLARIGINLANYGV
                     DIENGEHLMSEMVSRIVKTFMMTCGMYDASGEFAIKVGIPAKSGVGGGIMASVPGRMG
                     IGVYGPALDKKGNSVAGVKVLEELSNKLKLNIF"
     gene            10366..10929
                     /locus_tag="PC512_002106"
     CDS             10366..10929
                     /locus_tag="PC512_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2441847.1"
                     /translation="MKEVLVLRDLECIKAIAHPRRIDILKAFDKSPLSAKQLSQLLEE
                     PHAKINYHIKMLYKVGILELVEEKIKSGIVEKYYYPSAKNVVIGNRILNFSLDNGEEK
                     EELYISKFENMSEVFYKAAEEDVLENENIVDYHDISLTHDELVELSDTMKSKIDEILN
                     KRQHNVEGSKYDIAMVIVPTLEEECPS"
     gene            11417..12253
                     /locus_tag="PC512_002107"
     CDS             11417..12253
                     /locus_tag="PC512_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HDF2441848.1"
                     /translation="MIKLGTHLSIAKGFANAAETAVYIGANTFQFFSRNPRGGNAKEF
                     DEKDIIKFQEIRKENNFAPLLAHAPYTMNLGGTKDDVYEFATRVIDEDIRRMDSLGIE
                     YMCFHPGSHVGGGVDFGIDRIVKGLNNAIKGDENITILLETMSGKGTEIGFKFEQLKS
                     IIDKIEHKEKIGVCLDTCHIFSAGYDIVNDLDGVLEEFDKVIGIERLKTVHLNDSMMP
                     FGDKKDRHAPIGEGKIGLKALIDFMEHPSLKHLPFFLETPFDDEGHKKELKMIKEILS
                     SK"
     gene            12537..13532
                     /locus_tag="PC512_002108"
     CDS             12537..13532
                     /locus_tag="PC512_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HDF2441849.1"
                     /translation="MRNLGNTNMKIKRVGFGGIPIQRITQDDTNLVINELEKQGINFI
                     DSARGYTISEEAIGIAIEGKRDKFFLATKSMSRDYDSMKRDVEISLNNFKTDFIDLYQ
                     FHNVKEEEYDNLFKDKMAYSALLEAKEQGKIKHIGITSHNLNTIEKAIEDGKFDTIQF
                     PYNIVEGQADEVFKKAHEKGIGIIVMKPLAGGALDNATLAIKYILSKDYIDVVIPGME
                     SVEQVRQNVAVLENLVLDEKDNKEIEEIRNSLGKKFCRRCEYCMPCAVGINIPLSFLC
                     EGYYTRYGLKEWAKEKYEVMDVKPTECIDCGLCESRCPYELPIREMLKTVVEKLG"
     gene            complement(13789..14193)
                     /locus_tag="PC512_002109"
     CDS             complement(13789..14193)
                     /locus_tag="PC512_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HDF2441850.1"
                     /translation="MIKITIPGRPISKSNFKLHNINGQAWMPSKGKYSKYLAYENMIA
                     GFINQQYQGETVEENLITVLKLFFPNKRMGDLHNYPKSICDGIEKSGIIKNDKQLKPV
                     LLFDFIDKDNPRVEIELYPVSKYDISYNIFEK"
     gene            15034..15948
                     /gene="queG"
                     /locus_tag="PC512_002110"
     CDS             15034..15948
                     /gene="queG"
                     /locus_tag="PC512_002110"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HDF2441851.1"
                     /translation="MDNKELKAFCNLIGLNCVGVAGVDKYDNLEKILKNRQQKGYLTG
                     MEEPIIESRINPRHIMKDANSIIVCAFPYHINRQEKNKNSNLSKYCHGKDYHIVVKDF
                     LQQICDYISKTVTDFKYKLFADNGPLVDRYLAYLSGIGYFGINNNIITDEYGSYVFIG
                     YIVNNYKFEEDKPLEKSCFKCGKCVKYCPGNAILGNYDMNPKKCLSYITQKKGDLSEK
                     EKVVLKNGKKVFGCDICQEVCPHNVEIPTTHILEFKENIIDYLDYDEIQNISNKEFKR
                     RYGDRAFSWRGRNIIKRNMEIILDKYDD"
     gene            16054..18291
                     /locus_tag="PC512_002111"
     CDS             16054..18291
                     /locus_tag="PC512_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2441852.1"
                     /translation="MKYNNTSEINPLDYILGQERAVEAMELGLKINNPAYNIYIAGEP
                     GTGKSTYALKVLNEYASKKNTHKDWCYIYNFENPREPIIVELEKGFGRELKKDMEKLI
                     ESLLEDFKNAFESENFEIEKNKLLDEYEIEKDMLLKQIKKYGEEKGFKLKQSKMGIVF
                     IPLKEEEDESDESDEEFYKAKRELENMAIQVVYKIRNLEEIAEKAVLELEEEIAKLVV
                     EPHIKRLCEKYENYDKIQTYLENIKKDIIEYMYLFYLDEEELKDKYDKEHFIKYKINL
                     FVDNGSSKNKESAPVVVEINPSPANLFGKAEYDYANGNIKTDFTKLLSGAFHRANGGY
                     LVLYADQLLKYTMSWEILKKTLQTKKVILETQTAIKPENMPLDVKLVLIGSHYIYDIL
                     YRYDEDFEKYFKVFVDFDSEMDKNEDNEEGIARFIAYQCDKNNLRHFTKSAVEEVIKF
                     STRLSGDLEKLSTKFNKIMEVVIEGSAYAEFRNSEYTKQCDVKKAISEKRKRINRVET
                     HMDESIENGFTLIETEGRKVGVINGLSVLSTGEYSFGRASRITATTSPGSKGIVNIER
                     EVNMSGSIHNKGVLILGGYLSENFAQDLLLSLNAYVCFEQNYGGIDGDSASSAELYVL
                     LSSLSGVSIKQNIAVTGSINQKGDIQVVGGISEKIEGFYSICKTKGLNGEQGVIIPRK
                     NQRNLVLSDEVNDAVRDGKFKIYTVERVEEAIEILTDVKFEEIKKLVKEKLISFSKIQ
                     TVSKE"
     gene            18489..19706
                     /gene="nth"
                     /locus_tag="PC512_002112"
     CDS             18489..19706
                     /gene="nth"
                     /locus_tag="PC512_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HDF2441853.1"
                     /translation="MKNVNLKEINEKDVILEEEINKKGMDKKNIIEKEEINKKGIDKK
                     DIIEKEEINKKGIDKKDIIEKKEINKKGIDKKDIIEKKEINKKEMDKKDIIEKEEINK
                     KGMNKKDIIEKEEINEKEIDKMIGKKDEIIDEKDIENFMDIEEDKKSIKVSKKSTKKG
                     ETEKKTKKSSSNKATQKTSKETKSKFKIKNESANEKDVNKILDELEKLYPDAKCELNY
                     GTAFELLIATILSAQCTDVRVNKVTSELFKKYNTARDFANLSIEEISKEIKSCGLYKS
                     KSQKIKDTSEQLCELYDGEVPDSLEKLIKLPGVGRKTAGVVLSNAFNHPAIAVDTHVF
                     RVSNRIGIVDEPNPQKTEFALMEAIPKERWSHSHHVLIFHGRRMCKARNPECASCPIK
                     EDCNYYKELNETK"
     gene            19900..20370
                     /gene="trmL"
                     /locus_tag="PC512_002113"
     CDS             19900..20370
                     /gene="trmL"
                     /locus_tag="PC512_002113"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HDF2441854.1"
                     /translation="MSLNIVLVEPEIPQNTGNIIRTCAATGSTLHLVKPLGFSLDDKH
                     LKRCGLDYWDIADIQYYDSFEELQEKYPNSKYFFSTTKAKQSHSDVKYEENCFIVFGK
                     ETKGLPEPLLKANMDTCIRVPMLDVEKARSLNLSNSVAIVVYEALRQIGYPNMR"
     gene            20406..21254
                     /locus_tag="PC512_002114"
     CDS             20406..21254
                     /locus_tag="PC512_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HDF2441855.1"
                     /translation="MKNLKIICDSLSDVPKDLLDKYDIDIVSLTVILEEREYKDRIDI
                     SGDEFYKKLREENVYPKTSQATYAQFKEIFEKYTNEDREILYIAGSATATGTYQSAVM
                     AKNDVDGKIYTYDSNLLCMGTGLLVIKAGELASEGKSVAEILPVLDELKEKAFVIFSV
                     DTLEYLQKGGRISSTKAAIGSILNIKPILEIRDGLVSQISQVRGKKNVISKMMELIKS
                     NCGDDLSDQIVYIGYSDDFKEKEQLSKVMQDELRPKEIRFFQIGVCIGAHAGPGVTGI
                     ICLKNK"
     gene            21559..22563
                     /locus_tag="PC512_002115"
     CDS             21559..22563
                     /locus_tag="PC512_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF2441856.1"
                     /translation="MRFKRILILMLTVAMIAGMLVGCANNPSNNPSSSKDNKSDISDK
                     SNSKKSVSMILDIEGTNNEAMNNSALLALNNAQKKLNIDTNKVESDDSSTFSNSIDIL
                     CNDNYDLIIAVGARFAKPLEMVAKKYPKQQFAIIDYEYDKQPSNITSISYEDNKSGYL
                     AGLIAGKMTESDKVGFIGGTKSSSRDKFESGFREGVKFSNSSIKDISVEYADVFKDSK
                     SVESIAKKMMDNGVDIIFSTTEDDSKAVIDAVRAKNKKVIATNKDQHELAPENVISSI
                     VKDFENPTYNLIQSFVKGNYKGGKVIENTVKSGSTGLAQNSSQNIPPDVLEYVNKNNK
                     "
     gene            22689..23801
                     /locus_tag="PC512_002116"
     CDS             22689..23801
                     /locus_tag="PC512_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF2441857.1"
                     /translation="MKIKRILMACFVVVFTIFILAICNFDFGFDKVNKNNSNIDSAKS
                     KQSESKSLPTSAEKDKSNSKSKNKEDDTEDDSYVRKTIGVLLDTENLNNESYNNNVLS
                     ALKRADEDFDVRIKLEKPKTSKSFKESIEKLHKYEPDLIIAVGARFAEPIKEAATEYP
                     KQQFAIVDYTYKVQPANVISVSFQDNVTGYLAGLIAGKMTDTGKVGFIGGVEGSSRDK
                     YESGFRKGLKTSNKDAELLVKYSNIFENPESARTIAKEMRDSDRDVVFSATEDDSKRA
                     IQVARENGGKVIAINKDQYDMAPDNVISSIIKDVEQPVYELIKNVAKDGFKGSKVMEF
                     KIKDGELGLTSKSSRNIPPDVLEYIKKEYNKVKDTY"
     gene            24291..25052
                     /locus_tag="PC512_002117"
     CDS             24291..25052
                     /locus_tag="PC512_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441858.1"
                     /translation="MEFTREPFILDDDLCLALVDKRISYLMENELKLRNIEIIKTIEC
                     KELYESIKYHPDICICNLGKGDIIVAPNVYNQYKELLSRYKFNIIKGEANLLNRYPYD
                     IPYNIAIVGDYAIHNFKYTDKAILDYIENNKLKKINIEQGYSKCSICIVDRTSIITSD
                     KGIWKSMKNTEIECLLIEKGHINLFEMNYGFIGGCTGLISKDKLAFCGDVKKHPDYER
                     IKSFVESKNKEIVTLSCENLLDIGSIVPLMTRKER"
     gene            25055..25873
                     /locus_tag="PC512_002118"
     CDS             25055..25873
                     /locus_tag="PC512_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sporulation protein YtxC"
                     /protein_id="HDF2441859.1"
                     /translation="MVEKDNISSMKFLRNNNVNDRLIYTNDIVEVVIDSAKQEVLNKK
                     ILNGTKAEQRALNIDEISTEITSMIISIMKEKLLKEYILKCYGRTYPEDKNNIYIYSL
                     NIFAKKEIFMRETVFTRVRNYIEENDFINVEGFIRFRMREFMKYISAIGDIAVEEYLI
                     KKDQDEFIRVLKYFIDTQEEKIDLLKVHIMEDNTFVLYDKNGNKIDSIDDEEIINMVI
                     RENLNYEDFLISTLLTLCPKKIEILDLLNNNCSKEIIDTVEAIFENKVSIIMEN"
     gene            26053..26655
                     /locus_tag="PC512_002119"
     CDS             26053..26655
                     /locus_tag="PC512_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF445 family protein"
                     /protein_id="HDF2441860.1"
                     /translation="MDNLIRILILAVIGGFIGYVTNVVAIRLIFRPIEPIKIPILNIE
                     IVGLIPKRRAEIAANVGEIIQEEFLSMDEILANIITDEDKEEVVRYIKARVKIIIHEK
                     VSFIPSGIKNMIQDYLGEIIESEVKQSIDELSKNIINKANERIDIQKMVEDKINELDL
                     YELEEIIIRIAKKELKHIEFLGLVLGFLIGIAQGLITMFI"
     misc_binding    27114..27351
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            27415..29334
                     /gene="thrS"
                     /locus_tag="PC512_002120"
     CDS             27415..29334
                     /gene="thrS"
                     /locus_tag="PC512_002120"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HDF2441861.1"
                     /translation="MIKVALKDGSIKEFENAISVMDVAKSISEGLARNVVAASVNGEV
                     VGLDHIIDTDCDLNLFKFEDKEGKEVFRHTSAHILAQAIKRLYPEAKLAIGPSIENGF
                     YYDIDLDHRLVPEDLEKIEAEMKKIAKEDLKIERFELPRNEALELMKEQGEDYKVELI
                     SDLPESEIISFYKQGDFTDLCRGPHLPSTKKVKAVKLQSVAGAYWRGDENNKMLQRIY
                     GTSFEKNKDLEEYLHLLEEAKKRDHRKLGKELGLFMIPEEGPGFPMFLPKGMELKNEL
                     LKFWREIHRKAGYIEIESPIILNRKLWETSGHWYHYKENMYTVKIDDEDYAIKPMNCP
                     GGLIYYNSQLHSYRDFPMRVAELGRVHRHELSGALQGLMRVRAFTQDDSHIFMLPEQI
                     KDEIKGVANLIDGIYKTFGFEYNLELSTRPENSMGSDEEWEAAENGLREALEELGLPY
                     TINEGDGAFYGPKIDFHLKDCLGRTWQCGTIQLDMQLPRQFDNTYIGQDGEKHRPVMI
                     HRVAFGSIERFIGILIEHYAGKFPVWLSPTQVKILPISDKFMDYANEVKKELFDKGIR
                     VELDDRAEKIGFKIREAQLEKVPYMLIVGEKEVADNNVSVRSRDKGEIGSIKLDEFIA
                     SISKEIESRESIIQD"
     gene            30102..31193
                     /locus_tag="PC512_002121"
     CDS             30102..31193
                     /locus_tag="PC512_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HDF2441862.1"
                     /translation="MIEKVEEKSKIIKTSKEYKRTIIEEKDKEWTKKLNDILSRSSFS
                     NDELDKIKALIPKEILTNENVGEVVTEDGYAKPEYDEVFKSLFTLNNEYDLLVNFIND
                     ILKDAPYANRNIKPFTQIKRIIRVETDPTINYIGEKRPKLDILAEDEENNHINIEMQR
                     AFENDYLERAEYYLSRVHGRKLEEGKEYKEIGKTIGIHILNHVKYNHIEDYVNCLRLT
                     MDGHPDIYSSKTALYFIELPKIHKSDYIVNRIMLWGKLISNPSNLDVRVIAKNDSIIK
                     KALDRLKELGSNEEYLLNLKRGAYIMNKSRNFKEEIERETAIRVAKEKDYKIIIMLKK
                     NGFKLDDILNKFNDFDLSEDEIKEVYENN"
     gene            31863..33203
                     /locus_tag="PC512_002122"
     CDS             31863..33203
                     /locus_tag="PC512_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDF2441863.1"
                     /translation="MIKSSLFWNIFIAISFMIEWFLCKKMLDYTSEKRISNKKINFCV
                     VGIIVFADIIYFFDVPPNIRVIISMIITIAFYKISYDVGFIKSVLISLIYWMLLIATD
                     ALSISLTVWLNSINDMSSMGTGDIYRIESIILGKILLIVSLLLYRALKIKLNIEINKR
                     TLFYIVIPIVANIASFFVIFEYIFNPGSGSLIHNFQFVMISVVLLISSITLVLIAKKL
                     QQYNTLVVENNMIKNTLKYENEYYEDIEKKYLKTRLLSHDMKNHILCINAMIKKGIDV
                     TSYLNNLQVEIQSNDLLFNTGNFILDAILSEKKEVCDKNDIELKIGINFSCCEAVELV
                     DICHIFSNILDNAIEACNKIDSGNRVICVKGDVMQNFYLIRVENTKMNKIITKNGDIL
                     TDKKGSLHGLGIKSVKNSVNKYGGNVVIEYDDKKFVVKIAIPLRNVKKAVNHVI"
BASE COUNT        13326 a         3142 c         6097 g        10831 t
ORIGIN      
        1 gataatggtg gatagagtag taagaaaata aatagataaa gggatagaat aaatttaaat
       61 atggaaaatg aatatctaat aataagtgat taataaataa ttgtagatag attgtaaatt
      121 aaataaatct ttaatagaaa ggagaactat ttatatatta aatagtattt ataaatatga
      181 aaaaaggcga ttttatatgg agtggagttc ttatttgtat tattgctgtc ttagcaatac
      241 caagtagtag agaagtattt atggaagcaa caggtgcaca tccatatatt ggaggttttt
      301 taaagtttgc tgtattagct acaatgggag atttacttgg tgctagaatt ttgtataagg
      361 attggaaaat accagtagga gtattttata gagcaatagt ttggggaata ataggtgtag
      421 ttaccacata tggaatgtca atctactcat caggtgtagg tcaagcacaa gtggatggta
      481 tgcttccatt tgagggaata gcttttgcaa atgctctatt taagagtgca actatgaata
      541 tactaatgtc accaactgta tttttattcc ataaggttat ggactgtttt atagataaaa
      601 aatatgaggt tggaaagggg attaaggtaa aacttaaaga tgtggtaaat attgtggact
      661 ggaatgctta ccttggtttt agtgttttaa aaactatacc atttttctgg ataccatgtc
      721 atacaattgt attcttattc cctgctgagt atagagtaat tgcttctgca tttgcatcta
      781 tagctttagg tctaatattg gctttagcta ataagtctaa agttgcagtt taggttcact
      841 gatgaagata gtagtattat ttaaattagg aataactttt taaattaata ttatttgtat
      901 ttataataaa taataattta tataagaagt aatattctaa gtgatggata gtgttttaaa
      961 taataagaag taatactcta agtgatagat agtgttttaa ataataagga gtaatactct
     1021 aagtgagaag tagcatttta aataataagt gagattttaa ataaaaagta ggtttttcgt
     1081 tagaatagca ttttattaaa cttaaaaata aatataatat tttaaagaaa tctaagttgc
     1141 taagcactgt ttttaagaag cttaaaatcc cccatttaaa gttttaagat tctaaaaaaa
     1201 caagttataa ctaaaaaatg gctgttaaga ctacaatact tataagtaat acttatggta
     1261 tatattagtt cataacagcc atttttattt taaattaata attttattca ataatttgag
     1321 tttatgttct aaatcaagct ttaaattaaa ggatttaaag aagctattct agttgtagct
     1381 acataaactc tggatatttc ataccatgtt ttaaaatcta ctactccgct ttgaggtaaa
     1441 ccaaagattc cttggaatat cttaacagcg ttttctgtat ctgttccata gataccatct
     1501 tctataactt ttggtacagc tggataagaa ttagatatag catttaactg attttgtatg
     1561 gttctaacat actgtccaga agaaccaact tgtagtgtag taccagggaa tgacactggt
     1621 acaccactta ctataggcgc tctttcaaat actatctcat ctccatagaa atatcttagt
     1681 atactctcat agtcatatcc ttggtcacct aagtctttac tgccccattg agtcatttgg
     1741 tcaggacatt gggatttttg tccatcacaa tattgtgcta atagtggctg tcttgatgta
     1801 ggaggtcttt ttataaaagt attaaaaata gcatctacaa ctacgttaat tggttcaaat
     1861 aagtttctat tatttataaa cttatggtcg tatgctgttg ttgaagttat tgtaaagtta
     1921 tatcctttat ttctatacca ttcagtaaag actctattta aagtaaatga tattatagct
     1981 attacatttg cataaattgt ctgttcaggc caagttgaat atatttcaga tgatgctatg
     2041 tttttaatgt actctttaaa tggaatccaa tagtttggag ctgatgaatc ttctggcaaa
     2101 ccatcatgaa ctactataaa ttcaggcact acagggttat ctaatacaac gaaaccagta
     2161 ggaggtggta atggttttaa gttactttct ggaatcttag gaggataagt accatataga
     2221 gtatgttctc ctatgtcaaa aatcaactca ctttgtcttg agaaagaacg cttacttctt
     2281 gttctaggag acatgggaac tccttgtctt gcttcaattg tagctaacaa ctgtgttcct
     2341 tctatgacaa ctgtctcata tccatctgct atggcttcca ctatatactg gctataaggt
     2401 ctaacatcag atggttgtag agagtaatct acatctggtg ctggtaatac taaaccagtc
     2461 acttgaccag attcattact tcttaggttt tggtataaag ttgatgagct ttggctacca
     2521 ttagacattg aatatatgtt tactactgca ttttgaatag gtctattgtt agtagcatca
     2581 attatgctta ctgttaagaa accatcttgc atcaaatcac cctttcttta aatgaattta
     2641 gttcccttat atttcaagat atgaatatag cttaaaattt gttaaataat atagatataa
     2701 atttaaattt ttttgagtat ttgagtatat ttgtatttaa ataatttaaa ataatttaat
     2761 gtatatttta gtatgtattt aaaacacgaa taagttaaaa ataagtagat gatataaatc
     2821 ataaataaat caaaaatttt gaaaggaaaa taatctatga agctagattt atttttatta
     2881 gcaatagttc ctatattgat aggaatgttt tggataaggt ctaaagatag atattgtaga
     2941 gaacccctaa tccatctaat taaatttttt ttaataggtg cttttctaag tgttataatt
     3001 atacttttag aaaatttact gatgaagttt aatgtatttg aagggtattc agaactaata
     3061 tatgtatcat ttgtagttgc aggacttgta gaagaaggtg taaaagctct gatactgatt
     3121 cctgccctaa ttaaagaaaa acactttact gaaaagttag atggtattat ttactctgta
     3181 tttttagctt taggatttgc aacaattgaa aatatggttt atattttttc tgaaagtaga
     3241 aatctagcac tgcaagttgg tattaatagg gcagttatct ctataccagc tcatgtaatg
     3301 tttgcaatta ctatgggcta ctatatttct aagtataaat ttgagggaaa taaaaataaa
     3361 agacgtgagt atttgtttat ggcagtgtta attccaattt tattacatgg agtttttgat
     3421 ttcatattga tgatagaata tagatgggct attatattac ttatagttta tgtaataatt
     3481 ttgtggaaga taaatcttga taaacttgag aaatatatga atcactctaa aaaagtgttt
     3541 ttcggtaatc ttaggaaaaa gaagaagaaa taaaatttaa aggaaagaca taaataatta
     3601 aagtataata aatgacacac aagtaaagca gattgaaggg ggattataga tttgacagaa
     3661 ttaccaaatg aatttttaga agatattgaa gaaatactaa aagatgaata tgatgatttt
     3721 ataaaaagtt atgaggaaag taagactact gggcttagaa taaatacttt aaaaattgac
     3781 aagaaaaaat tatttgattt ggagttgttt gatttgaatc aaataccatg ggcagaagaa
     3841 ggtttttatt atgatgataa aattgacaga cctggtagaa atccactgca tgaggctgga
     3901 gcatactatt tgcaagagcc ttctgcaatg agtgtaatac caaaggcaga tattaaagag
     3961 ggtgaaaaag ttctcgatat gtgtgctgct cctggtggaa aatctacata tatactatct
     4021 aagctaaacg atacaggttt attggtttct aatgaaatta atgctagtag aattaaggct
     4081 ctaggggaaa atttagagcg atttggagcg agaaattgta ttataacaaa caccgattct
     4141 aatagcttaa gaaagacgtt taatgggtat tttgataagg ttattataga tgcaccttgt
     4201 tctgggcaag gtatgtttag gaaggatgag gttgccatat cagattggag ttatgcaaag
     4261 gtagtagaat gtcaatccat ccaaaaagag attataagag atggatataa aatgttaaag
     4321 aaggatggca ttttaattta ctcaacttgt actttttcaa gggaggaaaa tgagcatgtt
     4381 ataaatgagt ttatcagtga atatccacat gcagaactta ttgaaatgga aagattatgg
     4441 cctcataaga taaagggaga aggtcatttt gttgccaaaa taaaaaaatt agaagaagaa
     4501 gaatgtaatg tcaaagaatt aaaaataaaa aatttagata aagaaataaa ggattatagg
     4561 gagtttgaaa agaaattttt aaaggttgat ttttatagta ataaaaaaaa taaattttat
     4621 ttaagaggag aaaatttgta cctacttcct gaaatatatc cagatacgaa aaaactaaaa
     4681 gtattgagat atggtttgca tttaggggtt ttaaagaaga atagatttga gccttctcat
     4741 gcactatctc attacttaaa agttgaagat gtaaaaaatg ttgaaaactt cagtgtacag
     4801 agtgaatcaa ttcttaaata tttaaaaggg gatgttgtaa attctaatga tagtagagga
     4861 tgggttttgg tttcggttga aggaatacct ttaggttggg gaaaagaatc ttctggtgta
     4921 attaagaatc attatcctaa aggtcttaga aaagtatttt aaactattag aaaaaagaag
     4981 tataatattt atattgtagg tttatggtag attattttgc tgtagattga cttaatattt
     5041 aacacagagg agacgatttt agtgggtgaa gcagttaaaa aagaagttgt agaatggata
     5101 aaagtgattg tcatagctct tgttttggca tttgcaataa ctcgttttat agtgccaaca
     5161 atagtcaaag gagaatcaat gtatcctaca ttagttgaac gtgattattt gatagttaac
     5221 agaattgcgt acaaggtagg agagccaaaa tacaaagata taatagtatt caaaaccgac
     5281 ttaacagagg aaaatggaaa gaaaaaagat ttagtaaaaa gagttatagg tgttcctggt
     5341 gaccatgtaa aaatacaaga ctccaaggta tatgtaaatg ataagttgtt agatgagact
     5401 tcctatatac ataataatcg tactgatgga gatattgata tcgtagttcc agaaggaaaa
     5461 ttatttgcaa tgggagataa tagagaaaaa agtttagata gtagatacga tgaggttgga
     5521 ttggtcgacg agcataccat tttaggaaag gttctagtca gattgtatcc attttctaag
     5581 ataggaacta ttgactaaac atataaaatt tggagcaatc gctgattagc tgaaatcacc
     5641 agaccataca caatagttgt ctatataaaa aagacaacac cttatttagt agacttatct
     5701 aaaagatagt gtttaagaga cattatcaat aaagataata taactataaa ggagaatttg
     5761 tgaatgaatg aaactattaa agaagagatt gtagagtgga taaaaataat tattactgca
     5821 cttttttttg catttattat aactcgtttt ataaaaccaa cattagtaaa tggagaatca
     5881 atgtacccaa cacttaaatc acatgattat ttggtagcaa acaggatgac atataagtta
     5941 tcagaaccaa aatgtggaga tataatgata tttaagactg atttattaca agagaatgga
     6001 aggaaaaaag agcttgtaaa aagggttata ggtgttcctg gtgaccatct aaaaattaag
     6061 gattctaagg tttatataaa tggtaagtta ttaaatgaag tttcatatat acatgataat
     6121 tatactgaag gcgatattga tatggtgatt cctaagggaa aagtatttgc gatgggagac
     6181 aatagagaag ttagtttaga cagtagatat aaagaagtgg gattagtaga tgaagaaaat
     6241 attaaaggaa aagttatttt aagagtattt ccttttacag atataggtat ttttgagtag
     6301 gtgatttgta tggcagttgg tatagcgtcc ttattgttta atattgagga ggctttaaac
     6361 atttgtgaga gtataaagca aataactcat ttagagattg gaattgacaa tatatctgaa
     6421 tgtagtgagt tatgtaaata taaagagaga atttctaagt taggattatc tatagggata
     6481 cacttgccta tggaattaaa tacttgcgaa aacatagagt atatacgaaa ttcatggata
     6541 aattttattg agaagataga atttgaacta aaaggatttg atttaaggta ttttaacctt
     6601 catttgggat atgttatgac aaatagagtt agaaagaata gagacaaata tttaggaaat
     6661 agtgtggatt ttttagataa attaaataca aattcatatg tatgtataga gaatacttat
     6721 tcaaaaggtg gggatttttc aaatattgga aatatatctt atgattttga atatatattt
     6781 aagaggatta aaaattctaa gatttgtttt tgttacgata ctggacactg tttaattgat
     6841 gaggatgctt atgtaaagaa cttaaaggat aaaataagac tgatacactt aagtgataat
     6901 gatggtatca atgatacaca tgttggtata ggaagaggaa ttttatctga agaggggatt
     6961 aaagaggtct taacattaga tgcagaatat ttagtattag aaataaatta cgaagacatt
     7021 gaagatacta taagtaaatt gaataatatt gtaggagagg gttaaatacc tctctttatc
     7081 ttgttgatat gcctcattaa ttaaaattta tattcatcaa aaggaaggag atgttgaagt
     7141 gaaaaaaata aacttaaaaa tagaaggaaa agataaggaa tattcattag aagaaaattc
     7201 ccctggaatc agattgggag atatagcaaa agaattttgt gatgagcata agggttatat
     7261 aacacttgca gttgtagaca ataaactaaa agagctaaat tgtagagtta agaaggattg
     7321 tgagataaat tttttagata ctactaatga agatggagag agagtttact ttagagtcat
     7381 gtcatttata tttgtaatgg catgtagaga aatcttttgg gatagcagag ttacaataga
     7441 acattcacta tcagatgggc tatattgtga agttcatata gatagaaagc ttaaagaagc
     7501 agatgttgaa aatataaaaa acaagatgaa agagatagta aacaacgatt atgttataga
     7561 aaaaattgaa gttacaagaa atgaagctat ttctatcttt gaaaataatg aaatgtatga
     7621 aaaggcagag cttttgaaat acaaagagta tgatagtgct aaagtatata agtgtagaaa
     7681 ctatatagac catttttatg gttatatgtt gccatcaact ggttatataa aatcatttga
     7741 tattaagctt tataatggag gcgttataat tttaggacct agtgaagaag ataagactct
     7801 tcctatgaaa tttgtacctc aacctaagct atcaagtgta tattatgaag cagaagaatg
     7861 gtcaagactt atgggaattg acaaggtagt atctcttaat aaaataatag aaaacaatga
     7921 atatggagat ataataagga catttgaagc attgcatgaa aagaagctat ctcaaatagc
     7981 ggatatgata aaggatggca ataagagagt agttttaata gcagctccat cttcatctgg
     8041 aaaaacaagt tttgctcaca gattatcaat acatcttaga gtaaataatt taaatcctat
     8101 ttcaatttct ttagatgatt attttataga tagaaaacat actcctttag atgaatatgg
     8161 aaattatgat tttgaatcaa tttatgcaat agatttagag aagtttaact tagacttaaa
     8221 gaaactttta gctggtgaag aaattgatga tataagattc aattttaaag aaggtaagag
     8281 agaatacact ggtaaaaaga taaagataga ttcaaatcag ccaattatat tagaaggtat
     8341 acatgggcta aatcctattt taacatcatc tataccagat gaagataaat ttaagatata
     8401 cataagtgcc cttactcaaa taaatttgga tgaccataat cgaatcccta ctgctgattt
     8461 gagaatgata agaagaattg ttagagacta taattttaga ggatatagtg ctgataatac
     8521 tattttacaa tgggcatcag ttagaagagg agaaaagaag aatatattcc cgtaccaaga
     8581 ggaggcagat gctatattta actctgcttg tgtatatgaa ttggcagttt taaaacgatt
     8641 tgcgaaacct ttgttggaag agataaagga agataatcct gcacatattg aagctactag
     8701 attactaaag tttttgcagt attttgttga attggacgat acttctgaca taccaggtat
     8761 ttcaattctt agggaattta ttggaggaag taaaatagtt gattaatgtg tgtattatag
     8821 attgttttat gaagattaaa tggcatagca agtagtgtta ttggtttatg ttaagtatat
     8881 taagtgtaaa gtggagaatt aaattgatac agattttaaa gtttgagttg atatataaaa
     8941 aggcttgttt tatacttttg tatgaagcaa gctttttatt ttaaatttta cttttttgtt
     9001 taatattttg ttagtttatg tgattatttt ttaaaagagt aaaagagtaa aagagtaaaa
     9061 gagtaaaaga gtaaaagagt aaaaggtgtt gggttagaaa tttttggtgt tataaaaatt
     9121 taaattactg gattattaga ttgctggatt gctaaattac taggttgtta aattattgaa
     9181 ttactaaatt attaagctct ttaaactatt taaattgttt gaaaaatgaa ttgattcttg
     9241 tagaaaataa ttttaaagta taattttttt taacattgtt ttattatagt ataaacttgt
     9301 gctaaaatag aatatataac ataatataag aggtgcatat gaatacgtta gatgagacat
     9361 tattaaaaga aattataagt tctaataaga agtatactaa ttatggacaa gtcgctagtt
     9421 acatcccaga attaaaaaac gctagaagaa atgatttagg aatttgtatc atagatagcg
     9481 aaaataatct ttatagtgct ggaaactgta gcacaaagtt tactatacaa agtatttcaa
     9541 aaccaattgt gcttgctatg gcacttatgg ataatgattg ggaagacgtt ttttcaaacg
     9601 ttggaatgga gccaagtggg gacccattta attcaataat gaaacttgaa attaatgaca
     9661 caaaaaaacc ctgtaatcca atgataaatg caggggctat agtaaccact tcccttataa
     9721 atgggagttg tttagaagaa aaagaagaaa gaatgcttag tttctttaga aagttagcaa
     9781 aaaatgataa tataggaata aactatgatg tctataagtc tgaaaaaatg actggagata
     9841 gaaacagagc tatggcttac ttattgaaaa gtgatggatt tatcagaggg aatgtagaag
     9901 atgttctaga cctttatttt aaacaatgct caattgagat agattctgta gatttagcga
     9961 gaattggaat aaatcttgca aattatggag tagatataga aaatggtgag catttaatga
    10021 gtgaaatggt ttctaggatt gtcaagacat ttatgatgac ttgtggaatg tatgatgctt
    10081 ctggggaatt tgctattaaa gttggcattc ctgcaaaatc tggagttggg ggtggtataa
    10141 tggcttctgt gccgggacgc atggggattg gtgtttatgg acctgcgctt gacaaaaaag
    10201 gtaacagcgt cgcaggagtt aaagttttag aggagttgtc aaataaactc aaattaaata
    10261 ttttttaaaa tattaagaaa ggattttttt gacaacaaca tataatttaa tatataatta
    10321 aattgtaaag aaatatgaat taaataaatt ttttaggagg ggtcaatgaa agaggtattg
    10381 gtattacgag atttggagtg cataaaggct attgcgcatc cacgtagaat agatattcta
    10441 aaagcatttg acaaatcgcc attgtcagca aaacaattat ctcaattatt ggaagaacct
    10501 catgcaaaaa taaactacca tataaaaatg ttatacaaag ttggtatttt agaattagtt
    10561 gaggaaaaaa taaagtcggg gattgtggaa aagtactatt atccaagtgc aaaaaatgtg
    10621 gttataggga ataggatact taatttttct ttagacaatg gggaagaaaa agaagaattg
    10681 tacatatcaa aatttgaaaa tatgagtgaa gttttttata aggcagcaga ggaagatgtt
    10741 ttagaaaatg aaaatatagt tgattatcat gatatttctc ttactcatga tgaattagtt
    10801 gaacttagtg acactatgaa gtcaaagata gatgaaattt taaataaaag acaacacaat
    10861 gttgaaggtt ctaagtatga tatagctatg gttatagttc ctactcttga ggaggaatgt
    10921 cctagttaga gaattaatta tggattaatt aaagatataa tattagagat tgaacatcaa
    10981 aatttactta ataatcaaaa aatagttttt ggtatgggta aaacaatgat ttttaatctc
    11041 tatttttttg tttttttata cctattgtat ttgtaaataa tatgtatagt gtaagatgta
    11101 tacactatct aagaagtgct tagataatat acaaagtatg taagattata atatttgaaa
    11161 ttgattaaaa tgggtataat taaagtgtaa atattaaaat taaaaattaa tataaattaa
    11221 atcaatgcta gaaatatgtt aaaagaggac tgagattagt tgggatagaa catcccttag
    11281 agcttacgaa tttttagtga aaaagtacta tcaaatagga atctccatct tcatatgttg
    11341 gctaaatgta gttaaggtgg agtagttcaa aattaaaatt gagtacaagt agtagtacaa
    11401 ataaaaggag attaatatga ttaaattagg aacacatctt tcaatagcaa aaggatttgc
    11461 taatgcggct gagacagctg tatatattgg tgcaaataca tttcaatttt ttagtagaaa
    11521 tccaagagga ggaaatgcta aagaatttga tgaaaaagat ataattaaat ttcaagaaat
    11581 tagaaaagaa aataattttg caccactgct tgcacatgca ccatatacta tgaatctggg
    11641 tggtacaaag gatgatgtat acgaatttgc aacaagggtg atagatgagg atataagaag
    11701 gatggactca ttaggaattg aatacatgtg ttttcatcct ggaagtcatg taggtggtgg
    11761 tgtagatttt ggcatagata gaatagtaaa aggattgaac aatgccataa agggtgatga
    11821 aaatataact atacttcttg aaactatgtc gggaaaggga actgaaatag gttttaaatt
    11881 tgagcaatta aaaagtataa tagacaaaat tgagcataaa gaaaaaatag gtgtgtgtct
    11941 tgatacatgt catatttttt cagctggtta tgatatagtg aatgatttag atggggtttt
    12001 ggaagaattt gataaggtta taggcataga aagattgaaa actgtccatc taaatgatag
    12061 tatgatgcca tttggagata aaaaagacag acatgctcct ataggggaag gaaagatagg
    12121 attaaaagca ttaattgatt ttatggaaca tcctagtcta aaacatttac catttttctt
    12181 agaaactcct tttgatgatg aaggtcacaa gaaagagctt aaaatgataa aagaaatact
    12241 atctagtaaa taaaccttta ttaaaaatat gtgaaatact tcaccctcaa cataattagg
    12301 gtggagatac aatcatgaaa tgtgataatt taaattaatg gataggaata acaaaaattg
    12361 tatacaaatt aactgggtat aaagtatgat tatattatga atagactgat ataaaatata
    12421 attatactat gaatagtatg taaatatatt gcaaagattc tcataatttg ttgtataatt
    12481 aaagatgaca tatttatatt atataaaaaa ttattaaaag ttaggtgggg aaagatatga
    12541 gaaatttagg caatactaac atgaaaataa agagagttgg ctttgggggc attccaatac
    12601 aaaggattac tcaagatgat actaacttag ttataaatga gttagaaaaa caaggaataa
    12661 actttattga tagtgcaaga gggtatacaa taagtgagga agcaatcgga attgccattg
    12721 aaggaaaaag agataaattt ttcttagcta ctaaaagtat gtccagagat tatgattcaa
    12781 tgaagagaga tgttgaaata agtttaaata attttaaaac tgattttata gatttatatc
    12841 aattccataa tgttaaagaa gaggagtatg ataatctttt taaagataaa atggcttata
    12901 gtgccctttt agaggcaaag gagcaaggta agataaaaca tattggtata actagtcaca
    12961 atttaaatac tatagaaaaa gctatagaag atggaaaatt tgacactata caattccctt
    13021 acaatatagt tgaaggacaa gcagatgaag tgtttaaaaa agctcatgaa aaaggaattg
    13081 ggataatagt aatgaaacct ttagctggag gtgctttaga caatgcaaca ctggctatta
    13141 aatatatact atctaaagat tacatagatg tagttatacc aggtatggag agtgttgaac
    13201 aggttagaca aaatgtcgct gtacttgaaa atcttgtgct agatgaaaaa gataataagg
    13261 aaattgaaga aataagaaat tctttaggta aaaaattctg tagaagatgc gaatattgta
    13321 tgccttgtgc tgtaggaata aatataccat tgagtttttt atgtgaaggt tattatacta
    13381 gatatggatt aaaagagtgg gctaaagaaa aatatgaggt tatggatgtt aaacctactg
    13441 agtgtattga ctgtgggctt tgcgagagta gatgtccata tgaacttcct ataagagaaa
    13501 tgcttaagac tgttgttgaa aagctaggat agattttatt tattgaaatc ggtgtattaa
    13561 atttactccg atttcttttt attagatgtg gtcttatata caaatattaa atttacatag
    13621 ttatagctat tatataaatt taatatttgt ttaatactta ttaaatattt acttaatgct
    13681 ttttaaaaac atttgtttga gtatagacat aacacaatta ttattgttgt attagtatag
    13741 tttcaaatac tggagtatca atataatgtc gaataacaca taaaatcttt atttttcaaa
    13801 aatattatag gatatatcgt atttagatac tggataaagt tcaatttcaa ccctagggtt
    13861 atctttatct ataaaatcaa ataaaagtac tggcttaagt tgtttatcat tttttattat
    13921 tccacttttt tcaataccat cacaaatact ttttggataa ttatgtaaat cccccattct
    13981 cttatttggg aagaataatt tcaagactgt tattagattt tcttcaacag tttccccttg
    14041 atactgttgg tttataaaac ctgcaatcat gttttcgtat gcaagatact tagaatattt
    14101 tccctttgaa ggcatccatg cttgaccatt tatgttatga agcttaaaat tagatttact
    14161 aataggtcta cctggaattg ttattttaat caaatttttc accatcctta tacagtattt
    14221 attataatct gtatatgatt taaaagcaaa ttgttattta aagtgttttt acagagcttg
    14281 tttgtaaaat tttccacttt agatgtagta atataagata agtattttgc ttacaaattt
    14341 taaaatttga tatatgatgg gcatattcat attagactat tataagacct tcataatatt
    14401 aataagtata agtttagtaa agagagtaaa aagaaatcca tataagtcaa gtaaagactt
    14461 aataaatggc aatgtaaatg ggatattaat tataagaaaa aatcaatctt tttgcttaac
    14521 tatagaaaga atgtcaaaat ataactaatg atatttgaag ttttagagtt tatattaaaa
    14581 ggtaagaagg ttaagtgggt aaaaaaggtt gaatagatta aaaaggctaa gtatctaaaa
    14641 gagttaagta ggtaaaaaag ttaaataagt aaatgaaaaa ggctaagtat ctaaaagagt
    14701 tagtaggtaa aaaagttaaa taagtaaata aaaaagatga agtatctaaa agagttagta
    14761 ggtaaaaaac taaataggta aaaagatgaa gtatctaaaa gagttagtag gtaaaaaatt
    14821 aaataggtaa aaagacgaag tacctaaaag agttagtagg taaaaaaatt aaatagataa
    14881 aaagacgaag tatctaaaag agttaagcag gtaagaaaat tgaatagcta aaaagattaa
    14941 gtatttaaaa gagttagtag ctagaaaagg ttaaaaagac taaaaaaatt aaataaattt
    15001 aaaaagtcaa ttagattaaa aaggaataat tttatggata ataaggaatt aaaagcattt
    15061 tgtaatttaa taggattaaa ctgtgtagga gtagcagggg tagataaata tgataattta
    15121 gaaaagatac ttaagaacag acaacaaaaa ggttatttaa ctggtatgga agaaccaata
    15181 attgagagca gaattaaccc aagacatata atgaaggatg ctaactctat aatagtctgt
    15241 gcatttccat atcatataaa tagacaagaa aagaataaaa attcaaattt atcaaaatat
    15301 tgtcatggaa aggattatca cattgtagta aaggactttt tacaacaaat ttgtgattat
    15361 atttctaaaa cagtaacaga ttttaaatac aagttatttg ctgataatgg accattagtt
    15421 gacaggtatt tagcttattt atcaggaata ggatattttg gaataaataa taatatcata
    15481 actgatgaat atggttctta cgtatttata gggtatatag taaataatta taaatttgaa
    15541 gaagataaac cactagaaaa aagttgtttt aaatgtggta agtgtgtaaa atattgtccg
    15601 ggaaatgcta tattgggaaa ttatgatatg aaccccaaaa aatgtttatc atatataact
    15661 caaaaaaaag gagatttgtc agagaaagaa aaagttgttt taaagaatgg caaaaaggta
    15721 tttggatgcg atatttgtca agaagtatgt ccacataatg ttgaaatacc aacaactcat
    15781 attttggaat ttaaagaaaa tataatagat tatttggatt atgatgagat acaaaatatt
    15841 tcaaataaag aatttaaaag gagatatgga gatagagctt ttagctggag aggtagaaat
    15901 ataataaaga gaaatatgga aataatttta gataagtatg atgactaata ataagagtct
    15961 gtttcatata ctttaatgtg tatttacttt aacacttgtt gtgtaaaagt catattatat
    16021 cattaaagtt aaatatgggg aggtggggga atattgaaat ataataatac atctgaaata
    16081 aatccactag attatatatt gggtcaagaa agagctgtag aagctatgga attagggttg
    16141 aaaataaata atccagcgta caacatatat atagctggtg aacctggaac tggtaaaagt
    16201 acttatgcct taaaggtttt aaatgagtat gcatccaaaa aaaatacgca taaagattgg
    16261 tgttatatat ataattttga aaaccctaga gagcctatta tagttgaatt agaaaagggg
    16321 tttggaagag aacttaagaa agatatggag aaattaattg aaagtctttt agaagatttt
    16381 aaaaatgcgt ttgaaagtga aaattttgaa atagaaaaaa ataaacttct ggatgaatat
    16441 gaaatagaaa aagatatgct tttgaagcaa attaaaaaat atggagaaga aaaaggattt
    16501 aaattaaaac agagtaaaat gggaatagtt tttatccctt tgaaagaaga ggaagatgaa
    16561 agtgatgagt ctgatgaaga gttttacaaa gctaaaagag aactagaaaa tatggcgata
    16621 caggtcgtat ataaaattag aaacttagaa gaaatagctg aaaaagcagt gttagagctt
    16681 gaagaagaga tagctaaact tgtagtagaa cctcatatca agagattgtg tgaaaaatat
    16741 gaaaattatg ataagattca aacttatctg gaaaatataa agaaagatat aatagaatat
    16801 atgtatttat tctatttaga tgaagaggag ttaaaagata agtatgataa agagcatttt
    16861 attaaatata aaattaacct atttgtagac aatggaagct caaagaataa agaatcagca
    16921 cctgttgtag tagagataaa cccaagtcca gcaaatctat ttggaaaggc agagtatgat
    16981 tatgcaaatg gaaatataaa gactgatttc acaaaactat tatcaggagc atttcatagg
    17041 gctaatggtg gttatttagt actttatgca gaccaattac taaaatatac aatgtcttgg
    17101 gaaattctta aaaagacttt gcagactaaa aaagtaatat tggaaacaca aacagcaatt
    17161 aaaccagaaa atatgccatt ggatgttaaa ttagtactga ttggaagcca ctatatatat
    17221 gatattttat atagatatga tgaagatttt gaaaaatatt ttaaagtatt tgtagacttt
    17281 gatagtgaaa tggataaaaa tgaagataat gaagaaggaa tagcaagatt tatagcatac
    17341 caatgtgata agaataattt aaggcatttt actaaatcag cagttgaaga ggttattaaa
    17401 tttagcacta gattatctgg tgatttagaa aaattatcaa ctaagtttaa taaaataatg
    17461 gaagttgtaa tagaaggaag tgcttatgca gagtttagaa attcggagta tacaaagcag
    17521 tgtgatgtta aaaaagcaat aagtgaaaag agaaaaagaa tcaatagagt ggaaacacat
    17581 atggatgaat caattgaaaa tggatttact ctaatagaaa cagagggaag aaaagtagga
    17641 gtgataaatg gtttgtcagt cttaagtaca ggagaatact cttttggtag agcttcaagg
    17701 attacagcga ccactagccc aggaagtaaa ggcatagtaa atatagaaag agaagtaaat
    17761 atgagtggct ctatacataa caaaggagta cttatattag gtggctatct ttctgagaat
    17821 tttgcacagg atttactatt gtcactaaat gcatatgttt gttttgaaca aaattatggt
    17881 ggaatagatg gagatagtgc atcttctgca gaattatatg tactattatc atctcttagt
    17941 ggagtatcaa ttaaacaaaa tattgctgtt acaggttcta taaatcaaaa gggtgatata
    18001 caagtagttg gtggtataag tgaaaagata gaaggatttt attctatatg taaaactaaa
    18061 gggttaaatg gtgagcaagg cgtcataatt cctagaaaaa atcaaagaaa tctcgtttta
    18121 tcagatgaag ttaatgatgc agtgcgagat ggaaaattta agatatatac tgttgaaaga
    18181 gtagaagagg ctatagagat attgacagat gttaaatttg aagaaataaa gaaattggta
    18241 aaagaaaaat taatatcttt cagcaagata caaactgtgt caaaagaata agtttattat
    18301 agaatttaat gggtatttat gtataataaa aagcaagaac tttaataggt ttttgctttt
    18361 tttgtaaata tatataaatt aaattcttat tttgtatgtt ttatatattg atgtttattt
    18421 ttttgttgat atgattaaac tatttataaa tagcgtttta taaattggta ttttgaaggg
    18481 ggataattat gaaaaatgta aatctaaaag agataaatga aaaagatgta attttggaag
    18541 aagagataaa taaaaaagga atggataaga aaaatataat tgagaaggaa gagataaata
    18601 aaaaaggaat agataagaaa gatataattg agaaggaaga gataaataaa aaaggaatag
    18661 ataagaaaga tataattgag aagaaagaga taaataaaaa aggaatagat aagaaagata
    18721 taattgagaa gaaagagata aataaaaaag aaatggataa gaaagatata attgagaagg
    18781 aagagataaa taaaaaagga atgaataaga aagatataat tgagaaggaa gagataaatg
    18841 aaaaagaaat agataaaatg attggtaaaa aagatgagat aattgatgag aaagatatag
    18901 agaattttat ggatattgaa gaagataaaa aaagtatcaa agtaagtaaa aaaagtacta
    18961 aaaaaggtga aacggagaaa aaaacaaaga agagtagttc taataaggct acacaaaaaa
    19021 caagtaaaga aactaaaagt aagtttaaaa ttaaaaatga gtcagcaaat gaaaaagacg
    19081 taaataagat tttagacgag ttagaaaaac tgtacccaga tgctaaatgt gagttaaatt
    19141 atgggacagc ctttgaactt ttaatagcaa ctattttatc agcacaatgt actgatgtaa
    19201 gagtgaataa agttacttca gagttgttta aaaagtacaa cacagctaga gactttgcta
    19261 atttgagcat tgaagaaatt agtaaagaga taaagagttg tggtctttac aaaagcaagt
    19321 ctcaaaaaat aaaggataca tctgaacagc tatgtgaatt atatgatggt gaagtacctg
    19381 atagcttaga aaagcttata aaattacctg gtgttggaag aaaaacggca ggggttgtac
    19441 ttagtaacgc ttttaatcat ccagcaatag ctgtagatac tcatgtattt agagttagca
    19501 atagaatagg aatagtggac gagccaaatc ctcaaaaaac agaatttgca cttatggaag
    19561 ctataccaaa agaaagatgg tcacactcac atcatgtatt aatttttcat ggaagaagaa
    19621 tgtgtaaagc tagaaatcca gaatgtgcaa gttgcccaat aaaagaagat tgtaattatt
    19681 ataaagaact taatgaaacg aaataacttt tagaaagtaa gttgtacaag agggattttc
    19741 tgatataata atacttgtga aaatgttaga taaaaaacta ttatatacat gaaataaaaa
    19801 ttattattaa cattatttta tataatagta taatattatt gttattctgt ttataaaata
    19861 aaatttgata aataaaagcg atacttaggg aggattaaaa tgtcattaaa tatagtatta
    19921 gtagaaccag aaatacctca aaatacagga aatataataa gaacctgtgc agcaacaggt
    19981 tcaactttac atttagtaaa accactgggt ttttcattgg atgataaaca cctaaaaaga
    20041 tgtgggcttg actattggga tatagctgat atacaatatt acgatagctt tgaagaatta
    20101 caagaaaagt atccaaatag taaatacttt ttttctacaa caaaggctaa acagtcacat
    20161 tcagatgtga aatatgaaga aaattgtttt atagtatttg ggaaagaaac aaagggatta
    20221 ccagaacctt tgttgaaagc aaatatggat acttgtatta gagtgcctat gttggatgtt
    20281 gaaaaagcta ggtcattaaa tttatcaaat tcagttgcta ttgtagtgta cgaggcttta
    20341 agacaaatag gatacccaaa tatgaggtag tttcaacaag cctaaatgag aaaggagcat
    20401 acttaatgaa aaatctaaag ataatctgtg acagtttatc ggacgtgcca aaagatttgt
    20461 tagataaata tgatatagat atagtttcat taacagttat actggaggaa agagaataca
    20521 aggatagaat tgatatatct ggagatgaat tttataaaaa gcttagagaa gaaaatgtat
    20581 atccaaaaac ttctcaagct acttatgccc aatttaagga aatttttgag aaatatacaa
    20641 atgaggatag agagatactt tatatagcag ggtctgccac agctacaggt acgtatcaaa
    20701 gtgctgtaat ggcaaagaat gatgtagatg gtaaaatata tacatatgac tctaacttgc
    20761 tttgtatggg aactggttta cttgtaataa aagcaggaga acttgcaagt gaaggaaagt
    20821 ctgttgctga aatattgcct gttttggatg aattaaaaga gaaggctttt gttatatttt
    20881 cagtagatac attggaatat ttacaaaagg gaggtagaat atcatctact aaggcagcaa
    20941 taggaagtat attaaatata aaaccgattc ttgaaataag agatggatta gtttcgcaaa
    21001 tatctcaagt aagaggaaag aagaatgtaa tttctaagat gatggaattg ataaaatcaa
    21061 attgtggtga tgatttatca gaccaaattg tatatatagg atatagtgat gattttaagg
    21121 aaaaagaaca attatctaag gttatgcaag atgaattaag acctaaagaa attagatttt
    21181 tccaaattgg tgtgtgtata ggtgcacatg ctggtcctgg tgttactggt atcatatgct
    21241 taaaaaataa ataatatatt tttggatgac attatttatt tttttattaa attaggatag
    21301 aatattaatt attgagatgt taaattggat ttattttgga tgaaattaag tgttgatata
    21361 ttagatttag tttgtaggga agtgtgtaaa tagataagaa tctattgcac acttttttat
    21421 agtaagattt attaaaaaaa tttcaaaatg tacttgtaaa ttgtatataa aaaaattata
    21481 aataggatgt aaaagtaaat aggatgtaaa agtaaatagg atataaaaat atcgtaaatg
    21541 tatgaggagt gaaatttaat gcgtttcaaa agaatattga tattgatgtt aactgtagca
    21601 atgatagctg gaatgttggt tgggtgtgct aataacccaa gcaataatcc tagctctagc
    21661 aaagataata aaagtgatat aagcgataaa agtaattcaa aaaaatctgt atcaatgata
    21721 ctagatattg aaggaacaaa taatgaagct atgaataatt cagctttatt agcattaaac
    21781 aatgctcaaa agaaacttaa tatagataca aacaaagtgg aatcagatga ttcctcaact
    21841 ttttctaata gtatagatat tttatgtaat gacaattacg atttaattat agctgtagga
    21901 gctagatttg caaaaccatt ggagatggta gccaagaaat atccaaagca acaatttgca
    21961 attatagact atgagtatga caagcaacct tctaatataa cttcaatttc ttatgaagat
    22021 aataaatctg gatatctagc tggattaatt gctggaaaaa tgactgaaag cgataaggtt
    22081 ggttttatag gaggaacaaa gagttctagt agagataaat ttgaatcagg ttttagagag
    22141 ggtgttaaat tttctaatag tagtataaag gatatttcag ttgagtatgc agatgttttt
    22201 aaagatagca aatcagtaga atctatagct aaaaaaatga tggataatgg agtggatatt
    22261 attttttcta ctactgaaga tgattcaaaa gctgtaatag atgcagtaag ggcaaaaaat
    22321 aaaaaagtta tagcaacgaa taaagaccaa catgagttag ctccagaaaa tgttataagt
    22381 tctattgtaa aagattttga gaatcctact tataatctga tacaaagttt tgtaaaagga
    22441 aattataaag gcggaaaagt tatagaaaac acagttaagt ctggaagtac tgggcttgcc
    22501 caaaatagtt ctcaaaatat tcctccagat gtgttagaat atgttaataa gaacaataaa
    22561 taatctacta taatatccaa gaatacttat gactttagtt atgaggtgaa ttggatgtta
    22621 taatagacat atatagaaag acatatgcag aggtaggtca gacctatcta aatcagggag
    22681 tgaattttgt gaaaataaaa aggatattga tggcttgctt tgtagtagtt tttacaattt
    22741 ttatattagc tatatgtaat tttgattttg ggtttgataa agtaaataag aataattcta
    22801 atatagatag tgctaaatcg aaacagagtg agtctaaaag tttgccaact tcagcagaaa
    22861 aggataaatc aaatagtaaa agtaagaata aagaagatga cacagaagat gattcatatg
    22921 taagaaaaac tattggagta ttgttagata ccgaaaactt aaataacgaa tcatataata
    22981 acaatgtact atcagcctta aaaagggctg acgaagattt tgatgttagg ataaaacttg
    23041 aaaaaccaaa gacttctaaa agttttaaag agagtataga aaaactgcat aagtatgaac
    23101 cagatttgat aatagcagtt ggagccagat ttgcagagcc aattaaagaa gctgctactg
    23161 aatatcccaa acagcaattt gcaatagttg actatactta taaagttcag ccagctaatg
    23221 taatttctgt atcatttcaa gataatgtta ctggatattt agcaggactt attgcaggta
    23281 aaatgactga tactgggaag gttggtttta taggaggagt tgagggttct agtagagata
    23341 agtatgaatc tggatttaga aaggggctta aaacttcaaa taaagatgct gagttactag
    23401 ttaagtattc aaatatattt gaaaaccctg aatcagctag aactattgca aaggaaatga
    23461 gagattctga tagagatgtt gtattttcag ctacagagga tgatagtaaa agagctattc
    23521 aggtagcaag agaaaatgga ggtaaagtta tagctattaa taaagaccaa tacgatatgg
    23581 ctccagataa tgtaataagt tcaattataa aagatgtaga acaacctgta tatgaactga
    23641 taaagaacgt tgcaaaagat ggttttaagg gaagtaaagt aatggaattt aaaataaaag
    23701 atggagaact tggcttgact tcaaagagca gtagaaatat accaccagat gttttggaat
    23761 acataaaaaa agagtataac aaagtgaaag atacatatta attattgatg tagaagatta
    23821 taaaaatata ctgcttaagt ttagattggt gataaaagga tatatttatt aaatttgtgc
    23881 taactgtaca aaatatattg attaagttta gattagtgat aaaaagatat atttattaaa
    23941 tttgtgttaa cagtatggaa tatactgctt aagtttagat tggtgataaa aggatatatt
    24001 tattaaattt agtctaactg tacaaaatat attgattgag tttagattag caataaaaag
    24061 atatatttat taaatttgtg ctaactgtac ggaatatact gcttaagttt agattagtga
    24121 taaaaagata tatttattaa atttgaacca actgtacaaa gctatactaa ttaagcttag
    24181 attaactata taaaattata acaataagtg tgtgggcaga aaaattctgc tacacacttt
    24241 atttatattc acataaaaaa tttatcaaaa aaaagaaaaa ggagtaaaaa atggaattta
    24301 caagagaacc atttatacta gatgacgatt tgtgtctagc tttggtggac aaaagaatta
    24361 gttatctaat ggaaaatgaa ttaaaattaa gaaatataga gataataaaa acaatagaat
    24421 gtaaagaatt atatgaaagc ataaaatatc acccggatat atgtatttgt aatttaggaa
    24481 aaggagatat aattgttgcg ccgaatgtat ataatcaata caaagagtta ttaagtagat
    24541 ataaatttaa tataattaag ggagaagcta atttattaaa tagataccct tatgatatac
    24601 cttacaatat tgcgatagtt ggtgactatg ctatacacaa ttttaagtat actgacaaag
    24661 caatattaga ttatattgaa aataataaac ttaaaaagat aaatatagag cagggctatt
    24721 ctaaatgctc aatctgtata gtagatagaa cgtctataat aacatcagat aaaggtattt
    24781 ggaaaagtat gaagaataca gaaatagagt gtttattgat agaaaaaggt cacataaatt
    24841 tatttgagat gaattatgga tttataggtg gatgtacagg gttgatttct aaggataaac
    24901 tagctttttg tggagatgtt aaaaaacatc ctgactatga acgtataaaa agttttgtag
    24961 aaagtaaaaa caaggagata gttacactta gctgtgaaaa tttactagat ataggttcta
    25021 tagttcctct catgacaaga aaggagcgat aactttggtt gagaaggata atatttcttc
    25081 catgaaattt ttgaggaata ataatgtaaa cgatagatta atatatacga atgacattgt
    25141 agaagtagtg atagattctg caaagcaaga agtgttaaat aaaaaaatac ttaatggtac
    25201 taaagctgaa caaagagctt taaatattga tgagatatca acggaaataa ctagtatgat
    25261 aataagtata atgaaagaga aacttttgaa agaatacatt ctaaaatgct atgggcgtac
    25321 atatcctgaa gataaaaata atatatacat atattcactg aacatatttg ctaaaaaaga
    25381 gatttttatg agagaaacag tatttactag ggtgagaaat tatatagaag aaaatgattt
    25441 tataaatgta gaaggtttta ttagatttag aatgagagaa tttatgaaat atatttctgc
    25501 tataggtgat attgcagttg aggagtattt aataaagaaa gaccaagatg aatttataag
    25561 agttttaaaa tactttatag atactcaaga agaaaagatt gatttgctta aagttcatat
    25621 aatggaagat aatacatttg ttttatacga taaaaatgga aataagatag acagtataga
    25681 tgatgaagaa attataaata tggtaataag agaaaattta aattatgagg actttttaat
    25741 aagtacctta ttaactctat gtcccaaaaa aatagaaata ttggatttgt taaataataa
    25801 ttgctcaaag gaaattatag atactgtaga agcaattttt gaaaataaag ttagtataat
    25861 tatggaaaac tagaatctaa gcatataaaa gctatccata taaaattaaa aaaattcttt
    25921 ttaaatcgac acaaaagact tataattgta tataaagcta tagtataact agtgttatta
    25981 agtataaaga atatctactt gattaataca atatagctgg caaatataca attgataagg
    26041 agtaatttta taatggataa tttaattagg atactgatat tagctgttat tggtggattt
    26101 ataggttatg ttacgaatgt agttgctata agactgatat ttagaccaat agagcctatt
    26161 aaaataccta ttttaaatat agaaatagta ggtcttatac caaagagaag agcagaaata
    26221 gcagcaaatg taggagaaat aattcaagaa gaatttcttt ctatggacga aatacttgca
    26281 aatatcatta ctgacgaaga taaggaagaa gttgtaagat acataaaagc aagggtaaaa
    26341 attataatac atgagaaagt ttcatttatc ccgagtggta taaaaaacat gatacaagat
    26401 tatctaggag agataattga gtctgaagtt aagcaaagta tagatgaatt gagtaaaaat
    26461 ataataaata aagcaaatga acgtatagat atacaaaaaa tggtcgaaga taagattaat
    26521 gaactagatt tatatgaatt ggaagagata ataataagaa tagctaagaa agaattaaaa
    26581 catatagagt ttttggggct tgtcttaggg tttttaatag gtatagctca agggttaatt
    26641 actatgttta tttaaatata tgagaagtag catttattta agtactaatt atatttacct
    26701 atttgagtga attacttatt aatagcattt agatattaat tgtatttatt tatttgattg
    26761 tgttacttat taatagtatt taagtattta ctgtactact tattaactat attaagtatt
    26821 gattgtattt aagtatacaa aacctaaaaa gagtacaaaa attagaagtt agttttaata
    26881 aaaattagtt ttagtattta tctagtcata tctatcatgc atgtggatac gttttaaaaa
    26941 ttttaaattt atgaaaatat tataatatca ctataaatca agagattaat ttaatataaa
    27001 aatataagaa tattggttta cagctgattg agatgaaaaa taatgggtaa ttaatatatt
    27061 acattaatgt tgattgatgt ataactatct gttataatga aaatatatta aaaatcatag
    27121 tgttgaagag gaagagtaga gtagaaacca ttctcagaga atttgggtct atggctgaga
    27181 gcccatgtaa taggtctatt tgaaaactac cttggagctg agcttattag cagtatttgt
    27241 tttgtactat acgtgaaagt gctcgggtga cgaccttata gtcatcaaga gggttgtata
    27301 tacttgtata cgccaacttg ggtggaaccg cgaattaata tcgtcccaaa catatttggg
    27361 gcgatttttt attacaaaaa atctaaaaat tatttcaata aggaggaaaa aacaatgatt
    27421 aaagttgctt taaaagatgg ctcaataaaa gaatttgaaa atgctatttc tgttatggat
    27481 gtagctaaat ccattagtga aggattagct agaaatgtgg tagcagcgtc tgtgaacgga
    27541 gaggttgtag gtctggacca cattatagat actgattgtg acttgaattt atttaagttt
    27601 gaagataaag aaggtaagga agtttttaga catacatcag cacatatatt agctcaagct
    27661 ataaaaagac tttacccaga agcaaagctt gctataggac caagtataga aaatggattc
    27721 tactatgata tagatttaga ccatagatta gttccagagg acctagagaa aatagaagct
    27781 gaaatgaaaa aaatagctaa agaagattta aaaatagaaa gatttgaact tcctagaaat
    27841 gaagctttag agcttatgaa agaacaagga gaagactata aggtagaact tatatctgat
    27901 ttacctgaaa gtgaaataat atctttctac aagcaaggtg attttactga tttatgtaga
    27961 ggaccacatt taccatctac taaaaaggta aaagctgtta aattacaaag tgtagcaggt
    28021 gcatattggc gtggtgacga aaataataag atgcttcaaa gaatatatgg aacttctttt
    28081 gagaaaaaca aagacttaga agagtactta catttactag aagaagctaa aaagagagac
    28141 cacagaaaat taggtaaaga attaggatta tttatgatac ctgaagaagg tccaggattc
    28201 cctatgtttt taccaaaagg tatggaactt aaaaatgaat tattaaaatt ctggagagaa
    28261 atacacagaa aagctggata tattgagata gaatctccaa tcatattaaa tagaaaatta
    28321 tgggagactt caggacactg gtatcattac aaagaaaata tgtatacagt taaaatagat
    28381 gatgaggatt atgctataaa acctatgaac tgtcctggtg gattaattta ttataactct
    28441 caactacatt catatagaga tttcccaatg agagttgcag agcttggtag agttcataga
    28501 catgagttat ctggtgcatt acaaggatta atgagagtta gagcatttac tcaagacgat
    28561 tcacatatat tcatgttacc agagcaaatt aaggacgaaa taaaaggagt agctaactta
    28621 atagatggta tatacaaaac ttttggattt gaatataatt tagaattatc tacaagacca
    28681 gagaactcta tgggaagcga cgaagagtgg gaagcagcag aaaatggatt aagagaagct
    28741 ttagaagagt taggtctacc atatactatt aatgagggtg atggagcatt ctatggtcct
    28801 aagatagact tccatctaaa agattgttta ggaagaactt ggcaatgtgg tactatccaa
    28861 ttagatatgc agcttccaag acaatttgat aatacttata ttggtcaaga tggtgaaaag
    28921 catagaccag ttatgattca tagggttgct tttggtagta tagaaagatt tataggtata
    28981 ttaatagagc attatgctgg taaattccca gtttggttat ctccaactca agttaagata
    29041 cttcctatat ctgataaatt tatggattat gcaaatgaag ttaagaaaga gttatttgat
    29101 aagggtataa gagttgaatt agatgataga gctgaaaaaa ttggatttaa gataagagaa
    29161 gctcagcttg aaaaagtgcc atacatgcta atagtaggtg aaaaagaagt agctgataat
    29221 aatgtttctg ttagatcaag agataaaggt gaaataggta gtattaaatt agatgaattt
    29281 atagctagta tttcaaaaga aattgaatca agagaaagta ttattcaaga ctaatatata
    29341 ttatattagt agctaagata ttgttatata agataagttt aatcaatatg ttgatatgtt
    29401 gatgcatagt gattaaattt atgaaaagat gagtataatt agaggtacag ttaatcatat
    29461 ttttatgatt aatgtacctc tagttttttg tatggtagat ttattaataa atatatcata
    29521 gaagtgtttt gaacatggaa atatttatgt gcattcttta aataaacgtt tattttttga
    29581 gtgataatta agtgcttgtt ggtaaggtta tggctgtaaa aatcataact ttattttcat
    29641 atttgttcca ttttcataaa aattattatc cctttaagaa aatttcttaa tcctcttgaa
    29701 atatttcctt tttagtctaa agttaaattt ctttcttcaa aatgaatatt taaatgaact
    29761 aaaatttaag tacattttct aatcttatga gtctattttt catagataat tgccctataa
    29821 tagaagaatc tatgttggtg ctatgtggtg acaataacag cattgtcagt gattaattaa
    29881 tgctttataa atgattaatt agtgttttat gttatttttg gacttaccct ctatacatag
    29941 attaatttat ttaactttag atagagagag aatgtcaagt acatacacag acattagagt
    30001 ttaagaaagt gtttatggag caagaacttt taaaagaggt agtgacttag tttaatttca
    30061 agaaatgata aatacaaaag aggaaaaaga gaggtgttga aatgatagaa aaagtagaag
    30121 aaaaatctaa gattattaaa acatcaaaag aatataagcg aactataatt gaagaaaaag
    30181 ataaagaatg gaccaaaaaa ttaaatgata tacttagtag aagtagtttt tctaatgatg
    30241 aattagataa aatcaaggcg ttaattccaa aagagatttt gactaatgaa aatgttggag
    30301 aagttgtgac tgaagatgga tatgctaagc ccgagtatga tgaggtattt aaatcattgt
    30361 tcactttaaa taatgaatat gatttacttg taaattttat aaatgatatt ctaaaagatg
    30421 ctccatatgc taacaggaat atcaaaccgt tcactcaaat aaagagaata attagagttg
    30481 aaactgatcc aacaattaat tacattggag agaaaagacc taaacttgat attttggctg
    30541 aagatgaaga aaataatcat ataaatattg agatgcaaag agcttttgag aacgattatt
    30601 tggaaagagc tgaatattat cttagtcgtg tacatggtag aaagttagaa gaaggtaaag
    30661 agtataaaga aattggaaaa actattggaa tacatatact aaatcatgta aaatataatc
    30721 acatagaaga ttatgtaaat tgcctgagat taacaatgga cgggcatcca gatatttatt
    30781 ctagtaaaac tgcattatat tttatagagc ttccaaaaat tcataaatct gactatatag
    30841 taaatagaat tatgctatgg ggaaaactta ttagtaatcc ttctaactta gatgtaagag
    30901 ttatagctaa gaatgattct attattaaaa aagcacttga tagattaaaa gaattaggta
    30961 gcaatgaaga atatttatta aatctgaaaa gaggtgctta tatcatgaat aaaagtagaa
    31021 attttaaaga agagattgaa agagagacag caattagagt tgcaaaagaa aaagattata
    31081 aaataattat aatgttgaaa aaaaatggtt ttaaattaga tgacatatta aataaattta
    31141 atgattttga cttaagtgaa gatgagataa aagaagtata tgaaaataat tgatgataaa
    31201 taaaaagtga acttatataa gtttgctgaa tcggagtctg gaaatattta tgtgtatttt
    31261 ttaatgaatg aaaatttatt ttaaaaacaa taatttagaa gtacagttaa ttatattttt
    31321 atgatactgt acttctagtt ttttctattg tagatttatt atttactaat aaatctacaa
    31381 tagaaatgct tttgttgtaa gaatcatttt atctaatgat tgttttttat aatagttaaa
    31441 tttccatttg tagtgtttaa atataaatct ataacagcat ttctataaat gttataaatc
    31501 actataatga ttcaactcaa agttactgct taaagaagca gagattttat caaggtatat
    31561 catggaaaaa aatattttat tgtaatattt ataagatttt attatggaaa taatgtaaaa
    31621 actttataaa taatatattt tatacctagt tatagataaa tttatatagt tattattaaa
    31681 aaaagcaata aaaagtttaa ttcaatttag caaatttagt gatataatta aaaaagaaaa
    31741 gaaatatgga cttatttgga ataattttga caatctattt actacacgtg tagagtcgta
    31801 tataattaaa ttatacataa aatataaaaa aataatttag taatacgtta ggagaaagta
    31861 ttatgataaa gtcaagctta ttttggaata ttttcattgc gatatccttt atgatagaat
    31921 ggtttctttg taagaaaatg ctagattata caagtgagaa aaggatttct aacaaaaaaa
    31981 taaacttttg tgtggtaggt attattgttt ttgctgacat aatatatttt tttgatgtac
    32041 ctccaaatat aagagtaatt atatctatga taattactat tgcattttat aaaatctcat
    32101 atgatgtggg gtttataaag tctgtattaa tatccttaat ttattggatg ttactaatcg
    32161 ccacagatgc tttgagtata tctttaacag tttggcttaa ttctataaat gacatgagta
    32221 gtatggggac gggagatata tacagaattg agtctataat attgggaaag atacttttga
    32281 ttgtgtcttt gcttttatat agagccttaa agataaaact taatatagaa ataaataaaa
    32341 ggacattatt ttatatagtt attcctatag tcgctaatat agcatctttt tttgtaattt
    32401 ttgaatacat atttaatcca gggtctggta gcttaataca taatttccaa ttcgttatga
    32461 tttctgttgt attgcttata tcaagtatca ctttagtttt aattgctaaa aaattacagc
    32521 aatataatac tttagttgta gaaaataata tgattaaaaa tactttgaag tatgaaaatg
    32581 agtattatga agatatagaa aagaaatatt taaaaactag attactaagt catgatatga
    32641 aaaatcacat cttgtgtata aatgctatga ttaaaaaagg tattgatgtt acttcttatt
    32701 taaataattt gcaggtagaa attcagagta atgacttgtt atttaatact ggtaatttta
    32761 tattagatgc tatattaagt gaaaagaaag aggtttgtga taagaatgat atagaactaa
    32821 aaataggaat aaattttagt tgttgtgaag ctgttgaatt agtggatata tgtcatatat
    32881 tttcaaatat tttagacaat gcaattgagg catgtaataa aattgatagt ggaaatagag
    32941 ttatttgtgt taaaggtgat gttatgcaaa atttttattt aataagagtt gaaaatacta
    33001 agatgaataa gattattact aaaaatggag atattttgac agacaaaaaa ggttctcttc
    33061 atggacttgg aataaaaagt gtaaaaaact ctgtaaataa gtatggtggt aatgttgtaa
    33121 ttgaatatga tgataaaaaa tttgtagtta aaattgctat tccacttaga aatgtgaaga
    33181 aagcagttaa tcatgtgatt taaatgtata taaatttgat gtgtagaaat ttaatatata
    33241 agaattaatg tataaaagtg atgcatagaa gtttaatata taagaattaa tgtataaaag
    33301 tgatgtatag aagtttaata tataagaatt aatgtataaa agtgatgtat agaagtttaa
    33361 tatataagaa tttaatatgt ataaaagtga tgcata
//
LOCUS       DAMJVG010000042        33314 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.042, whole genome shotgun sequence.
ACCESSION   DAMJVG010000042 DAMJVG010000000
VERSION     DAMJVG010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 33314)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33314)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33314
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.042"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            <1..582
                     /locus_tag="PC512_002123"
     CDS             <1..582
                     /locus_tag="PC512_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF2441864.1"
                     /translation="NHIGLDLGIKEFCISSCGDFIENPKYLKKSLNKLAKLQRELSRK
                     TIGSLNRNKARLKVAGLQEHIANQRNDFLQKLSTKLIKENDIICIEDLQVKNMIRNRK
                     LSRLISDVSWSEFIRQLEYKANWYGRKIVKVGKFFASSQICNKCGYKNEEVKDLNIRE
                     WICPSCNETHDRDINASINILKEGLRLITIQNK"
     gene            700..1005
                     /locus_tag="PC512_002124"
                     /pseudo
     CDS             700..1005
                     /locus_tag="PC512_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438308.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
     gene            1018..1923
                     /gene="truB"
                     /locus_tag="PC512_002125"
     CDS             1018..1923
                     /gene="truB"
                     /locus_tag="PC512_002125"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HDF2441865.1"
                     /translation="MNKIISILKPTGMTSHDVVSRVRKILNIKKVGHTGTLDPDASGV
                     LPICIGKATKVCEVILNKDKSYICELTLGISTDTYDASGEILKKVDDFKFSNEDIERA
                     FDTQRGEINQLPPIYSALKVNGKRMCDLVRSGRQSEITLKTRRVNIKDIKILSIKGNK
                     VMFYVECSKGTYVRSICHDIGEYLGCGAHMSFLNRTSSGKFDLDNSITLEELELFYEN
                     KTLDKYLYDIDYVLDSFNYVVLNPNAIKYYSNGGSIDDKRFLKNNFDKDDEFVRVYST
                     DNFLGLGKLSKHNNTISVKSDKMFI"
     gene            2054..2983
                     /locus_tag="PC512_002126"
     CDS             2054..2983
                     /locus_tag="PC512_002126"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HDF2441866.1"
                     /translation="MVIIKSIKEIANIKESVITIGNFDGVHKGHQVLIGKTVEHAKKE
                     NIQSIVFTFANHPVNYFRPNSTKNIISNDDKIKLLEDLGIDIVVIIPFDEYMTKIPAK
                     DFVDEILVKKLKAKKIVIGHDFTFARAKEGNVNLLKSLEHEFGFEVEVIKPIKINDVR
                     VSSTYIRSLVSQGDMANVKEYLGRNYKLEGCVIHSKHLGRTIGFPTANIDLKNNMLVP
                     KRGIYASIVHIGDETYFGATNVGYNPTVNGKTLSIETNILEFDRDIYGENIIVEFLER
                     IRDERKFNSIDDLKNQLYNDTNYVYENYVCKNK"
     gene            3087..3344
                     /gene="rpsO"
                     /locus_tag="PC512_002127"
     CDS             3087..3344
                     /gene="rpsO"
                     /locus_tag="PC512_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002843739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HDF2441867.1"
                     /translation="MINKSEIIKEYGRAEGDTGSPEVQIALLTARINELNGHLKTHKK
                     DHHSRRGLLKMVGRRRNLLAYLKEKDLEGYRALIAKLGLRK"
     gene            3584..4429
                     /locus_tag="PC512_002128"
     CDS             3584..4429
                     /locus_tag="PC512_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HDF2441868.1"
                     /translation="MKIKLVCDSLCDIPDEISEKDYIEIVPLTVIFNDREYIEGVDIK
                     KEEFYKKVKEIKQIPKTSQATYMEFKEVFDKFITEGYHIICMTGAANASGTFQSAMIA
                     KNDVNENEKIHIFDTRNLSLGSGQYVIKACELLEEGLGFEEIIDELENTRSSVRLLFA
                     PYTLDFLKQSGRVPVATALIGNMLNIKPIFFFDNGEAKLVNKVRGIKNIASKLVDIIL
                     EMNEGSLEGKIVTIGCGDNLHDCEILKDEVNKRIKARRVLFTRGGVSICSHTGPDILA
                     ISCSN"
     gene            4554..6665
                     /gene="pnp"
                     /locus_tag="PC512_002129"
     CDS             4554..6665
                     /gene="pnp"
                     /locus_tag="PC512_002129"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HDF2441869.1"
                     /translation="MFEHKIFKMDFAGRELSVEIGKICEMASGSCIVRYSDSMVMVNT
                     TKSAKPRDGIDFFPLSVDYEEKLYSVGKIPGGFLKREGKPSEKAILTSRLIDRPIRPL
                     FPKGFRNDVQVVATVLSVDQDCTPDIVAMIGSSIALSISDIPFNGPTGSVCVGLVDGA
                     FVVNPNAEQREKSSMHLVVSGTKEAIMMVEAGADEVPDEVMLDAILFAHQEIKKIVEF
                     IEGIVAEVGKEKMPVELYHAGEEITQLVREFATDKMKKAVQTFEKLERMENMDRVKEE
                     TLAHFEETLEDFEDFVGDIEEVLQDIIKEEVRKLIVHENVRPDNRKLEEIRPIWCETG
                     MIPRAHGSAIFTRGQTQVLNVATLGALGDVQKLDGLDEEENKRYMHHYNFPAYSVGEA
                     RPSRGPGRREIGHGALAERALLPVIPSQEEFPYAIRLVSEVLSSNGSTSQASVCGSTL
                     SLLDAGVPIKDMVAGIAMGLIKHDGKVAVLSDIQGMEDHLGDMDFKVAGTEYGITAIQ
                     MDIKIDGIDKEILQRALKQAKEGRIHILGEMRKTISQPKPELSPYAPKIVKMQINPDK
                     IKDVIGPGGKIITKIIDETGVKIDIEQTGEVFISGIEIDMIKKAQELINNIVVEPEVG
                     KTYKGKVSRIMNFGAFVEILPGKEGLLHISHIAHERVAKVEDVLNIGDEVEVKVTEID
                     EKGRVNLSRKVLLPKPEHKNK"
     gene            6931..7674
                     /locus_tag="PC512_002130"
     CDS             6931..7674
                     /locus_tag="PC512_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDF2441870.1"
                     /translation="MIMMVLNKSKLKKIIILILVVLLVLSGGVMVLKLFNNKPVFNLF
                     NGVDLPYERGTKDKSGYVALTCNIDLGWETEYVESILETLKKENVKITFNVTGKWAEK
                     NKDELLKIKKQGHEIGNHGYKHLDYSTLSYEDNYEQIETSKKIIEEIIGEKTKFFQAP
                     AGSFGPETVKAAKALGYTSIKWDADTIDWKYKDQPEVIIDRMKKKDIKDSSIILMHPT
                     NATTKCIDDIIAIVREKGLKPGKLSDVFK"
     gene            7832..9079
                     /locus_tag="PC512_002131"
     CDS             7832..9079
                     /locus_tag="PC512_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HDF2441871.1"
                     /translation="MYKTKILENGLTIIGEEIPYLKSITLGIWINAGSRIEEAQVSGI
                     SHFIEHMMFKGTKNRTSKEIASSIDNLGGQINAFTSKECTCYYVKLIDEHIDTGIDVL
                     SDMILNSKFDKNDIDKERLIILEELKMYEDSPDDLSYDLLVENIYANDGLGMNIIGTK
                     ESLYNITRESMLEYLNKYYIPNNAVISIAGNFNFDDMVEKIKSKFGHWEKKNLSIDIS
                     EAKFNPCFISKNKDTEQVNLAMCLKGIPFENDEEVYSMAVVNNIFGGSISSRLFQKIR
                     EEKGLVYSIYSSQTLYRKCGELGIFASMSTENLQDVYNLIKKEIENIRENYLTEKEIS
                     ESKEQLKGNYILDLESTSSRMMSTGKSMLLSKKVKTTDEILECINNVNINSIKKVVDK
                     VFNIENIGTCIVGRDVEKILHLD"
     gene            9114..9359
                     /locus_tag="PC512_002132"
     CDS             9114..9359
                     /locus_tag="PC512_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlmC/YmxH family sporulation protein"
                     /protein_id="HDF2441872.1"
                     /translation="MNLSEIAGKEIVNLVTGERLGVIGECDLILDETTGDILALLIPK
                     EKGFFARRKDKSFLEVPWRNVKKIGNDMIIIEYEGYI"
     gene            9369..10592
                     /gene="dapG"
                     /locus_tag="PC512_002133"
     CDS             9369..10592
                     /gene="dapG"
                     /locus_tag="PC512_002133"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HDF2441873.1"
                     /translation="MSILVQKFGGTSVESYEKMNEVCKIVKAYKKNDEELQLVLVVSA
                     MGRKGAPYATDTLINLCSAVNDEPSKRELDLIMSCGEIISGTILANLLNAQGIDSVFF
                     TGQQAGIITSDEYSNAKIKYINPKKVKRALDDGKVVVIAGFQGVTDDGEITTLGRGGS
                     DTSAVAIGKALECETVEIYTDVDGIMTADPRVEPNAKVLSFIDYEEVFQMADKGAKVI
                     HPRAVQLAKSGNITLAIKNTMNPTFEGTKIGSLCRHLEDNIEYEQERDFKVAVANKDS
                     VAQVKIKSAEEVFTEVLNEIEKKLITIDMINFFISEKAFVVEDADIKSLKEILDKFEL
                     DYEVNRDCAKVTLICSRIADEMSGIMSKVVRGLSKAGVSLLQTSDSNMTISCLVSEED
                     MHTAVHAIHQQFYLK"
     gene            10705..11439
                     /locus_tag="PC512_002134"
     CDS             10705..11439
                     /locus_tag="PC512_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="HDF2441874.1"
                     /translation="MKDYREDNEKFDKDNCSEESSCEERECIKQFGTNEMPPQPPKDI
                     QCITIIGEIEGHFIGNPQKKATKYEHIIPMLYSIEESNDVKGVLVVLNTVGGDIEAGL
                     AIAELLNSTSKKVVTLVLGGSHSIGVPLATAGDYSFIAPTATMIIHPVRTTGLVIGIN
                     ETFEYFKKMQDRIIQFIIRTSNIKKDVLEKLMHEKDELVSDVGSVLIGKEAVDYGLID
                     EVGGLKEALKKLRELIKESEEEKNND"
     gene            11562..13973
                     /locus_tag="PC512_002135"
     CDS             11562..13973
                     /locus_tag="PC512_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HDF2441875.1"
                     /translation="MATKKKKKKKVNTLSFNAEYHNLITIFIGVFLLYSLNSNSMGWI
                     PVLMQNLFKGLFGGLSIAIPFIVIITGLLGFFDGNEYIYRLRKTKLYYIIILFIFVFY
                     GLLNAGTLPVDSPLKGNMFDDVMKLGVSGQGSGLIATTIAYYMSKIFGIAGGWLISIF
                     ALILSVMFIFNISIKDLVSNAKSKSKASKDSNLTFKDKIANMKKSAIDMMTDEVDDTT
                     INKKPGFFKGLMSKGLNNDDEEDEYFEEENSDGVDDKTIKIVGFNKAEDEYLEILEGT
                     QSMPELDVLKELQKATNENPVVDTKPEKKVDIAKPNLNIEKTQPMSIVAEPVNEDYSN
                     YKKPSIELLNKVNKKSDENGKKKVLKNASLLEKTLSDFGVEAKINQVTVGPTITRYEI
                     QPSPGVKVSKIVNLTDDIALSLAAKSIRIEAPIPGKSAIGIEVPNEEAQMVGVREVLE
                     SEEFNNFNSPLAMGLGKDVAGKIIIGDIGKMPHLLIAGSTGSGKSVCVNTLISSILYK
                     ANPDEVKLLLIDPKVVELANYNGIPHLLIPVVTDPKKAANALNWAVTEMNRRYKLFAD
                     AQVKDVTSYNEKAEEKLPKIVIIIDELADLMMASANDVEDYICRLAQMARAAGMHLIV
                     ATQRPSVDVITGVIKANIPSRIAFAVSSQTDSRTILDMGGAEKLLGKGDMLFYPLGAA
                     KPVRLQGAFISESESEKVIDFVKSQVKDGIKYEEDIIETISKVNTSKGSDEDEFLSEA
                     IEFVVESGQASASMLQRRFKIGFNRAARLIDSMEERGIIGASEGSKPRKVLISKQDLQ
                     NLEGE"
     gene            13976..15034
                     /gene="mnmH"
                     /locus_tag="PC512_002136"
     CDS             13976..15034
                     /gene="mnmH"
                     /locus_tag="PC512_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-selenouridine(34) synthase MnmH"
                     /protein_id="HDF2441876.1"
                     /translation="MSVIKIEKALKLDKVIFVDVRTEGEYEEDHILNAINMPLFKNNE
                     HNEVGTIYKMQGKHEAIQKGFDYVSYKLKDIYLQAAELALNYDNIVIYCARGGMRSGS
                     IVNLLSSLGVNVYQLEGGYKAYRNFVLEYLRHVMDTKNFVSVHGLTGTGKTDLLHLLD
                     EKGIDVLDLEGIAKNSGSTFGFITFDKKPPSQKNFETKLFESIFFSKENYIFVESESK
                     RVGSVTVPNEIFEAMTREGHHILLECDIENRVDRLCRDYIYDKDEGNILILKECINKF
                     RKRLGNKVVDDYIDLLESGEYKELVKRYLLEYYDPLYMHSVEKYKYSKIINFNDTQKA
                     LEDVIDLYESILEGESEC"
     gene            15028..16362
                     /gene="rimO"
                     /locus_tag="PC512_002137"
     CDS             15028..16362
                     /gene="rimO"
                     /locus_tag="PC512_002137"
                     /EC_number="2.8.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12 methylthiotransferase
                     RimO"
                     /protein_id="HDF2441877.1"
                     /translation="MLKIALESLGCSKNLVDAEIMMGILNNKGYKLIGDFEEADVIIV
                     NTCGFIESAKQESIDTIINFAELKKTGNLKLLIVTGCLAQRYSEELKTEIPEIDAIVG
                     TGSYQNIDKILKELSEMHQIVSLNDIEFVFNEDLPRYISTPSYMAYLKIGEGCSNNCT
                     YCIIPKLRGKYRSRKFEDIIKEAKKLAESGVKELVVIAQDTTKYGFDLYGKERLSELL
                     EELAKIDGFKWIRVMYSYPESITEELIQVIKKYDNICSYFDMPIQHASNNILKLMNRK
                     TTKEDILNKINLIRSNIPDAILRTTIIVGFPGETEDDFKQLVDFVEEVKFDRLGAFAY
                     SREEDTPADRLPNHIDEEVKIQRRDTLMMIQQKISEELNDKKIGKTYEVLIEEQIEDN
                     VYTGRTQGDAEEIDSIVYVKSVDNLEVGEFVSVQINDAMEYDLMGDVLYELA"
     gene            16349..16891
                     /gene="pgsA"
                     /locus_tag="PC512_002138"
     CDS             16349..16891
                     /gene="pgsA"
                     /locus_tag="PC512_002138"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HDF2441878.1"
                     /translation="MNLPNKLTLFRIFLIPVFVLIMLLNVPNKFLIACIIFIIASITD
                     ALDGKIARKYNLVTDFGKFMDPLADKLLVISALTCMIEDHLVSSWMVIIIVARELTVS
                     ILRAIAAADGKVIAAGNSGKLKTITQMVSIVFLLLGAQFENVLILNIGEILILIATLL
                     TLYSGWEYLYKNKELFMSSK"
     gene            17179..18225
                     /gene="recA"
                     /locus_tag="PC512_002139"
     CDS             17179..18225
                     /gene="recA"
                     /locus_tag="PC512_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HDF2441879.1"
                     /translation="MSVDQEKLKALNEALGKIEKDFGKGSVMKLGEATSMSIDVISTG
                     AIGLDIAIGIGGLPRGRIVEVYGPESSGKTTVALSCVASAQKDGGIAAFIDAEHALDP
                     VYAKALGVDVDNLIISQPDTGEQALEIAEALIRSGAIDIIVIDSVAALVPKAEIDGDM
                     GDSHVGLQARLMSQALRKLTGSIKKSNCVAIFINQLREKVGIMFGNPETTTGGRALKF
                     YSSVRLDVRKIDTIKQGDKVIGSRTRVKVVKNKVAPPFKQAEFDIMYGEGISKIGDLL
                     DIAADVDIVKKSGSWYSYNDTKLGQGRENVKKFLEDNLDLTTEIDEKVRAFYNLNEEH
                     EESGISVSKEIVEE"
     gene            18401..19942
                     /gene="rny"
                     /locus_tag="PC512_002140"
     CDS             18401..19942
                     /gene="rny"
                     /locus_tag="PC512_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HDF2441880.1"
                     /translation="MDVIDSVVMIVIGAAVGIIAGYFVRKNISEAKIGQAENLAKEII
                     DKAHHDSETVQKEKLLEAKEEIHKWRTEAERENRERRTEVQKYEKRVVQKEEVLDRKL
                     QNLESKEVNLSEKLKVVEKKEEEVEVIKTQQLEKLESISGITSDKAKEIILTNAERDV
                     RREMSIMIKEIESQAKEEADKKSREIIGYAIQKCAADHVAETTVTVVSLPNDEMKGRI
                     IGREGRNIRTLETLTGIDLIIDDTPEAVILSGFDPIRREIARIALEKLIADGRIHPAR
                     IEEMVEKARKEVDNIIKEYGEQAAFETSVHGIHPELIRLLGRLNYRTSYGQNVLKHSI
                     EVAHIAGIMAAEIGADIRLAKRAGLLHDIGKAVDHEMEGTHVEIGMDLLRRYKESKEV
                     IHAMSTHHGDYEPQTVEAVLVTAADAISAARPGARRETLEAYIKRLEKLEEIANSYEG
                     VEKSFAIQAGREIRIMVKPEAINDEEIHLLARDMTKKIEDELEYPGQIKVSIIRETRA
                     IEYAK"
     gene            20577..22358
                     /locus_tag="PC512_002141"
     CDS             20577..22358
                     /locus_tag="PC512_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HDF2441881.1"
                     /translation="MSQYININSQLDALKLKEFEKIFYENINEDVKVVPKVTPFKGIN
                     TDLLYVKDGRILFIKFMDTTEDIFFILEEELLEVMNEEYELLKLKMGQKNRNISYNYV
                     YIMPYVEVEETYEFEEFVNNNIIDKNKLQDIMNKGSLEEYLNDENDEINLNLFLLDIC
                     SEYYIINDKLHLNEKFKKISFYNDDYKYTATMMEDVQIKDVVSIKYGNTLIEGGSGIG
                     KTAIMLSRAIKLAKVYPHHKLVIFTHTKQLCNELRERIELLYKDNNNLEVHTFSSFIF
                     KLAKKFNLIVDYNMLKNDYEKTFNNLVKQAQNIIKNKNMFKAIFIDEAESFLEYEIDF
                     IREFLYKTKFIFNVCSCNSLNISNRLNIFKKLYNGIEFDDKIILSKNYRQAKEIVDFT
                     NKFSNNSNSYINELRPNTEFSTFFYTKALRGGNKSVDIIKVSDLDDQISSVIWEIEYL
                     ISKKGLDYSEVAIVYPYNKKKLKSGKTIYFQYMLKKALEEAKIPYICAEDNLTNISKK
                     VGTTIANIYAIKNLEYKAVIVCELEMLYNQTINDIEQDYQVNDFVGDLNKVYLAMSRA
                     TDYLSIVTTFNEEASDIIRLITESKDI"
     gene            complement(22440..22970)
                     /gene="lepB"
                     /locus_tag="PC512_002142"
     CDS             complement(22440..22970)
                     /gene="lepB"
                     /locus_tag="PC512_002142"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HDF2441882.1"
                     /translation="MSVKKEIFDWIKSIAMAIVLAFVILQFIRPSIVSGESMYPTLDD
                     KDYLILNRISYKVGKPEKGDIVVFKTNLVDGETGKKKDLIKRVIATEGDRIKISNSKV
                     YVNGKLLNEPYIHNNYTSGDIDTVVPKGKLFAMGDNRENSNDSRFPDVGMVDEDEVLG
                     KVMVRLLPLDNIGKVD"
     gene            complement(23010..23834)
                     /locus_tag="PC512_002143"
     CDS             complement(23010..23834)
                     /locus_tag="PC512_002143"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HDF2441883.1"
                     /translation="METFSLLEIFKAVILGIVQGITEWLPVSSTGHMILVDEFIKLNF
                     SNTFISTFLVVIQFGSILAVLVIFFRKLNPFDSAKNIKQKKETVRLWLKVIIAVIPSG
                     VIGILFEDDIDRLFFNSTVVAIALIVYGIIMIGLEKRNKKPKYKDFSQVTYKLALCIG
                     LFQCLALIPGTSRSGSTIIGAVLLGTSRYVAAEFSFFLAIPTMLGASALKLLKAGFGF
                     TGFEWLILGVGSVVAFVVSIVVIKFFMDYIKKHDFKVFGYYRIVLGIVVLAYFFLL"
     gene            24091..24999
                     /locus_tag="PC512_002144"
     CDS             24091..24999
                     /locus_tag="PC512_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDF2441884.1"
                     /translation="MYSTKILDDYEYETFNVFSTKLNPNTKHDYLSKVILFKEFLKGK
                     ELIYATKEDCKNFVDYIQTKYAKSTCEKIYSYLHSFYNFLKKEGYIDINPFRYVEKPT
                     VTRIKTKDDVLSIQEINKLIGILPKLNIRDRVIIVCLVTTGCLLNELVSLKWKDLMVD
                     ENDNSYVRLGKGRKERVVKLHPYFFKLLEDYRNYSGLPEVIIPSDDFIFTTQKSNSIT
                     DRNVRLIVKKALDLAGLSQYSARDFRHSFAAISLRLGADESDVKNQLGWSDKYYAIRY
                     KYVLNFVDSEIVDYLIEKDNLDINKK"
     gene            25143..26588
                     /locus_tag="PC512_002145"
     CDS             25143..26588
                     /locus_tag="PC512_002145"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HDF2441885.1"
                     /translation="MIDNKYTTYSNPLTDRYCSKDMSYIFSPQFKFSTWRRLWVALAE
                     GEHELGINITEEQLDELRANIDNINFDEARKIEKEVRHDVMSHVKAYGLQCEKAKGII
                     HLGATSAYVGDNTDVIQMNEALKLLRVKLVNLINNLKEFALKYKDMPALGFTHFQAAQ
                     LTTVGKRACLWAQDLILDLEDLNYRIDNMKLRGVKGTTGTQASFLSLFEGDHEKVKEL
                     DKKICKKMGYHSSYAVSGQTYTRKLDYQVISILSGIAQSMHKMTNDIRLLQSLKELEE
                     PFEKNQIGSSAMAYKRNPMRSERIASLSKYIISESISPAMVQATQWLERTLDDSANKR
                     LAIPQAFMAADAILEIGINVTDGLVVYENMINRRVNEELPFMATETILMEAVKRGGDR
                     QELHEIIREYSMKAAYRVKHEGKDNNLIELIMNDDSFKMSKEEILSIMDPKNFIGRAP
                     EQVVEFVNEVVEPAIKDYKEDLGKVDVDLRV"
     gene            26899..27351
                     /locus_tag="PC512_002146"
     CDS             26899..27351
                     /locus_tag="PC512_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2441886.1"
                     /translation="MNYIVKDTISFLVKTFPKIYSSLYLEDLKKFAPDYNVNKTQLRA
                     LVFIKNYGVISMTDLCSKLNIEKGSLTSMVDDLTDKKYVTRKRDLVDRRKYLIDITEE
                     GDKIATDFMDKLSDGLGEKLSKLTEEDRKKYLEAINTLQYILNKEEFR"
     gene            27763..29340
                     /locus_tag="PC512_002147"
     CDS             27763..29340
                     /locus_tag="PC512_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDF2441887.1"
                     /translation="MKQKMKGFFLQLGKSFLLPIALISAAGIFLGISSAFSNPNIVSD
                     MPFLANNFIQGILGFTKAITGVLFGNLAIFFAISISVGLAKEEKAVSAFSGFVGYLVL
                     HTSVNYMLGCRGIIAEPDMMREMGQAVTLGIQTLELGVFGGIVVGIITASLHNKYYNI
                     KLPDYLGFFGGTRFVPIITTVVFSILGIIIPYIWPYVNTIIQSVGIGIASLGYLGTFV
                     FGFLERLLIPFGLHHILNAMFRFTEVGGSLVVGGQEVFGALNIFLAQLSDPETISFST
                     EATRFLAQGKIPIMVFGLPAAAYAMYKTAKPENRSKVKGILLAGALATFVTGITEPLE
                     FSFLFVSPILFVIHAFLSGISFMMMHIFGVAIGNTQGGIIDLVVFGVMQPNTKWIYSI
                     ILGLVYAIVYYNVFKILILRFNLQTPGREEITDINFDLKPLSNKVEIAQSGETTKRAL
                     SIIKYLGGKDNIEDITNCITRLRVVVKDMSKVDENAFKKYTGAMGVIKVSDKDIQIIY
                     GPSVSQVRDEVSFAMSI"
     gene            29488..30240
                     /locus_tag="PC512_002148"
     CDS             29488..30240
                     /locus_tag="PC512_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF2441888.1"
                     /translation="MNLIDKLDINQKKLSTNEISLLNYFLKNSEKINQKKIKDIANET
                     FNSTAYIVRFCQKLGFSGYSEFKNFLVFSYSNRNERNKEFTKSQSDIFTDVMDTQNLI
                     NVENIDMCLNEIHNSKHIYFFGVGSSRLVCTEMSQRFSAIGVNVKYYDDSTLMYLAAS
                     NITKDDLVIAVSMSGETAQVIKACNIAKTNQVKVISLTNISVNSLSNIADIKLFVSSP
                     QYNFNSVNYTSRVPALSLMEYMFHKYIEKYNR"
     gene            30379..31719
                     /locus_tag="PC512_002149"
     CDS             30379..31719
                     /locus_tag="PC512_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HDF2441889.1"
                     /translation="MKKRYNIAIVGGGSTWTPGLLKSLCKMSDRFPLNKVTMLDVVEE
                     RQRLIGEFGKILFKEEYPKATLEYTTNPDEAFIDVDFVFVQMRTGGLKMRELDEKIPL
                     QFGLVGQETCGAGGFAYGLRSIGDMIEMVKTVRKYSPKAWILNYTNPAAIVAEALKRV
                     FPDDKRLLNMCDQPVNLLRSYGRLLDMDSRTFEPVYFGLNHFGWFTHLYDKNGEDLVP
                     KIKDLVANSGFQPVDAEQRDKSWLDTYGMVKDMLEDVPDYLPNTYVQYYLYPDKKVAK
                     SNINCTRAREVMNGREKRVFEECKSVIEKGTSIGSNLVHNDAHGEFIVEVAEAIAHNK
                     HQIAIVITENNGAISNLPDDAMVEVAAILTKNGPRPLHVGNIPTFYKGLLEGQLAYEK
                     LAVDAYFEQSYEKAILSLTLNRTIISPTKARQVLDALIKVNKDYWPTLYKENEK"
     gene            complement(31831..33027)
                     /locus_tag="PC512_002150"
     CDS             complement(31831..33027)
                     /locus_tag="PC512_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDF2441890.1"
                     /translation="MNYSNRVSAMQASPIRKLVPFAQAAKDKGIKVYHLNIGQPDIKT
                     PKGFFDAVKNFDSEVLEYATSEGIPELLEALQNYYKTYDMNFEKDELLVTNGGSEALL
                     FTMMAVCDPGDNLLVPEPFYTNYNGFGQSVNVEVNAVTTKAENGFHLPSKEEILSKVD
                     DKTKAIILSNPGNPTGAIYTKEELNILAEIAKEKDLWIIADEVYREFVYDGLEYTSCG
                     NLEGVQDRVIIIDSVSKRYSACGARIGSIACKNKGLIAQILKLCQGRLCVPTLEQIGA
                     VELYKTPVSYFKEVNEEYKKRRDVLYNELMKVEGVICKKPTGAFYIVAKLPVENAEDF
                     TIWMLKEFNKDNETVMVCPAEGFYATPGLGRDEIRLAYILNEKDLHRAATLLKEGLEQ
                     YVALQK"
BASE COUNT        13380 a         3640 c         5895 g        10399 t
ORIGIN      
        1 aatcatatag gtttagattt aggaattaaa gaattttgta tctcaagttg tggagacttt
       61 atagaaaatc ctaagtatct taagaagtca ttaaacaagc ttgctaaatt acaaagagaa
      121 ttatcgagaa aaacaatcgg tagtttaaat agaaataaag caagattaaa agttgcagga
      181 cttcaagaac atatagctaa tcaaagaaat gattttctac aaaaactatc tactaaatta
      241 ataaaagaga atgatattat ttgcatagaa gatttacaag taaagaatat gattagaaat
      301 cgtaaactat ctcgcttaat ttcagatgta tcatggtcag aatttattcg tcaattagaa
      361 tacaaggcta attggtatgg tagaaaaatt gtaaaggtag gtaaattctt tgcaagttca
      421 caaatatgca ataaatgtgg gtataaaaac gaggaagtta aggatttaaa tataagagaa
      481 tggatttgtc ctagttgtaa tgaaactcac gatagagata taaatgcaag tataaatata
      541 ttaaaagaag gattaagact aataacgatt caaaataaat aacttatgta agaaccgtag
      601 gaactacggg gatagcctgt ggagaattag taagacatat tttaatatgc aaaattctgt
      661 gaagcaggaa ccctgtgact ttagtcatgg gaggttcagt caaaggtatc tagtatagtt
      721 ttaactcaag acatgatgaa tagaaataat attagcttta atgatgttga tggaataaca
      781 acatatacaa gagacataaa aggtatagaa gttggaattt tatttaaaga gaaaaaacaa
      841 aatgaaatta aagtgagttt taggtcaaaa aattatgttg atgtaagtga aatagccaag
      901 ttatttggtg gtggtggtca tgtaagggct gctggatgta ctattagaga tagtattgat
      961 aatgcaaaga aaatggtact agaggcagtg ttaaaatcaa tttaaggtga cagtaaaatg
     1021 aataagatta taagtatatt gaaacccaca ggtatgacat ctcatgatgt tgtaagtaga
     1081 gtgagaaaga ttttaaatat aaaaaaagtt ggtcatacag gtactcttga cccagatgct
     1141 tcaggtgttt taccaatctg tatagggaaa gctacaaaag tatgtgaagt tattttaaac
     1201 aaagataaat cgtatatatg tgagcttact ttaggtataa gtacagatac ttatgatgct
     1261 tcaggtgaaa ttttaaaaaa agttgatgat tttaaattta gtaatgaaga catagaaaga
     1321 gcttttgaca cacaaagagg agagataaat caacttcctc caatttattc agctttaaag
     1381 gtaaatggaa agagaatgtg tgatttagta agaagtggta gacaatctga aattacttta
     1441 aaaacaagaa gagtaaatat aaaagacata aaaatactaa gtataaaagg taataaagta
     1501 atgttttatg ttgagtgttc taaagggact tatgtgagaa gcatttgcca tgatatagga
     1561 gaatatctag gttgtggagc tcatatgtcg tttttgaata gaacatcttc tggtaaattt
     1621 gacttagata attcaataac attagaagaa ttagaattat tttatgaaaa taaaacttta
     1681 gacaaatact tatatgatat agattatgtc cttgattcgt ttaattatgt tgtattaaac
     1741 cctaatgcta taaaatatta tagtaatggt ggctcaatag atgataaaag gtttttaaaa
     1801 aataatttcg ataaagatga tgaatttgta agagtataca gtacagataa tttcttagga
     1861 ttaggaaaat tatcaaaaca caataataca ataagtgtta aaagtgataa gatgttcata
     1921 taaccaatgt atttaaaaaa acaacaaaag agatagtact ataataactt ctatagtcta
     1981 tctcttttac ttatgctata atagtttgtg aataagttaa gagtaaatta tattttagcg
     2041 gggaacattt attatggtga ttataaaatc tataaaagaa atagcaaaca taaaagaaag
     2101 tgtcattacc ataggaaatt ttgatggtgt acacaaagga catcaagttc ttataggaaa
     2161 aacagttgaa catgcaaaaa aagaaaatat acagagtatc gtatttacat ttgcaaatca
     2221 tcctgtaaat tactttagac caaactcaac aaaaaatatt ataagcaatg atgataaaat
     2281 aaaattatta gaagatttgg gaatagatat agttgtaatc ataccatttg atgagtatat
     2341 gactaaaata cctgcaaagg atttcgtaga tgagatacta gtaaaaaaat taaaagctaa
     2401 aaagatagta attggacatg actttacatt tgcaagggca aaagaaggca atgttaatct
     2461 attaaaaagc ttagaacatg aatttggttt tgaggtagaa gtaataaaac ccatcaaaat
     2521 caatgatgta agagtgagta gtacttatat tagaagttta gtatcccagg gtgatatggc
     2581 taatgtcaag gaatatttgg gtagaaatta caagttagaa ggttgtgtta tacattctaa
     2641 acaccttgga agaactatag gattcccaac ggcaaatatt gaccttaaga ataatatgct
     2701 cgttccaaag agaggtattt atgcttctat tgtacatatt ggagatgaga cttattttgg
     2761 tgctacaaat gtaggctata acccaacagt taatggaaaa actttgtcta ttgaaacaaa
     2821 tattttagag tttgatagag atatttatgg ggaaaatata attgttgaat ttttggaaag
     2881 aataagagat gaaagaaagt ttaattcaat agatgactta aaaaatcaat tgtataatga
     2941 tacaaattat gtgtatgaaa actatgtttg caaaaacaag taatgtatga taaaatgatt
     3001 aaggaaaata accattactc agcatttgaa tactccaatc aatgcttagt aataggcgtt
     3061 tctaaaaaaa tacggaggta atctaaatga taaacaaatc agaaataata aaagaatatg
     3121 gaagagctga aggggatact ggttctccag aagtacaaat agctttatta acagctagaa
     3181 taaacgagtt aaatggacat ttaaaaactc ataagaaaga ccaccattca agaagaggac
     3241 tattaaaaat ggttggtaga agaagaaact tattagctta cttaaaggaa aaagatcttg
     3301 aaggatatag agcattaata gctaaattag gattaagaaa gtaatttcat tctttataaa
     3361 aaagcaggta tagtgtatac ctgctttttt atagttaatt cattataaag taaaatagtt
     3421 aataataaaa gtagtttata tgttataaaa aattataaaa tgaataatat tgggtaagaa
     3481 tattaaaata gtatacaaat acataatcaa tttaaaagga aagacaggat aaatatagaa
     3541 attttataac aggataatta gttggaataa ggaggatatt attttgaaaa taaagttagt
     3601 atgcgatagt ttgtgcgata ttccagatga aatatcagaa aaagattata tagagatagt
     3661 tccacttaca gttattttta atgataggga atatatagaa ggagtagata taaagaaaga
     3721 agagttttat aaaaaagtaa aagaaatcaa gcaaatacct aaaacttcac aagctacata
     3781 tatggagttt aaagaagtgt ttgataagtt cataacagaa ggttatcata taatctgtat
     3841 gacaggggct gcaaacgcat caggaacttt tcaaagtgct atgatagcta aaaatgatgt
     3901 aaatgaaaat gaaaaaatac atatatttga tactagaaat ttatctctag gtagtggaca
     3961 atatgttata aaggcatgtg aacttcttga agaaggactg ggatttgaag aaattataga
     4021 tgaattagaa aatactcgca gtagtgtaag attgcttttt gcaccatata cacttgattt
     4081 tttaaagcag agtggaagag ttccagttgc aactgctttg ataggaaata tgttaaatat
     4141 aaagcctata tttttctttg ataatgggga agctaagttg gtaaataagg ttagaggaat
     4201 aaagaatata gcaagtaaat tggtcgatat aattttagaa atgaatgaag ggtctttaga
     4261 aggaaaaatc gtcacaatag gttgtggaga taatttacac gattgtgaaa tattaaaaga
     4321 tgaagtaaat aaaagaataa aagcaagaag agtattattt actcgaggag gagtttctat
     4381 ttgctctcat acagggccag atatattggc tataagttgt tctaattagt agtaatataa
     4441 ggtttttgca tatatatgtg aagataattt tatattgtta atttatagta tttttgataa
     4501 tatagtaaat agagtgatat acgtgttttt taataagagg aggacaagca ttaatgtttg
     4561 aacataaaat atttaaaatg gattttgcag gaagagaact ttctgtagaa ataggaaaga
     4621 tttgtgaaat ggctagtggt agttgtatag ttcgatacag tgatagtatg gtaatggtaa
     4681 atacaactaa atcagccaaa cctagagacg gaatagactt ttttccttta agtgtggatt
     4741 atgaagaaaa attatactct gtaggtaaga tacctggagg ttttttaaag agagaaggca
     4801 agccttcaga gaaagctata cttacatcaa gattgataga tagaccaata agacctttat
     4861 tcccaaaagg atttagaaat gatgttcagg tagttgcaac agttctatca gtagaccaag
     4921 attgtacacc agatatagta gcaatgatag gttcttcaat agccctttct atatcagaca
     4981 taccatttaa tggaccaaca ggttcagtat gtgttggcct tgtagatggt gcatttgttg
     5041 taaatccaaa cgcagagcaa agagaaaaaa gttcaatgca tctagttgtt tcaggtacaa
     5101 aggaagcaat aatgatggtt gaagccggag ctgatgaagt tccagacgag gtaatgcttg
     5161 atgctatttt atttgctcac caagaaataa aaaaaatagt tgagtttata gaaggtatag
     5221 ttgcagaagt tggaaaagaa aaaatgcctg ttgaattata ccatgcagga gaagaaataa
     5281 ctcaattggt tcgcgaattt gcaactgata agatgaaaaa agcagttcag acttttgaaa
     5341 agttagagag aatggaaaat atggatagag ttaaagaaga aactttagct cactttgaag
     5401 aaactttaga agattttgaa gattttgttg gagatataga agaagtatta caagatataa
     5461 taaaagaaga agtaagaaaa cttatagtac atgaaaatgt aagaccagat aatagaaaac
     5521 ttgaagaaat aagacctata tggtgtgaaa ctggcatgat acctagagct catggttcag
     5581 ccatatttac tagaggacaa actcaagtac ttaatgttgc tactttaggt gctttaggag
     5641 atgttcaaaa actagatggg ttagatgaag aagaaaacaa gagatatatg catcattata
     5701 atttccctgc atatagtgtt ggagaagcta gaccatcaag aggaccagga agaagagaaa
     5761 taggacatgg tgctttagca gaaagagctt tattaccagt aataccatct caagaagaat
     5821 ttccttatgc tattagatta gtttctgaag tattaagttc aaatggttct acatctcaag
     5881 caagtgtatg tggctcaaca ttatctttac ttgatgcagg tgtacctata aaagatatgg
     5941 ttgcaggtat agcaatggga cttataaagc atgatggtaa ggttgcagtg ctttcagata
     6001 tacaaggtat ggaagaccat ttaggcgata tggactttaa agtagctgga acagagtatg
     6061 gtataacagc aatacaaatg gatataaaaa ttgatggtat agataaagaa attctacaac
     6121 gtgctttaaa acaagctaaa gagggtagaa tccatatact aggagagatg agaaaaacta
     6181 tatctcagcc aaaaccagaa ctttcaccat atgcacctaa gattgttaaa atgcaaataa
     6241 atcctgacaa gataaaagat gtaataggac ctggtggaaa gataataact aagataatag
     6301 acgaaactgg agttaagata gatattgaac aaactgggga agtatttata tcaggtattg
     6361 agattgatat gattaagaaa gctcaagaac ttataaataa tatagtagtt gaaccagaag
     6421 taggaaaaac ttataaaggt aaggtaagta gaataatgaa ctttggagca tttgttgaga
     6481 tacttccagg aaaagaagga ttacttcata tatctcatat agctcatgaa agagttgcca
     6541 aagttgaaga tgtattgaat ataggggatg aagttgaagt taaagttaca gagattgatg
     6601 aaaaaggaag agttaattta tcaagaaaag ttcttttacc aaaaccagaa cataaaaata
     6661 aataacttat tatataatta aaagcaaagt cttaggattt tgctttttta aatacaaaaa
     6721 agtagataat tttaaaatga tagttatgga tggcttatag ttctttttct gtcaggcttt
     6781 actcttataa agaagctatt taaaagctga ttaatagaga gctttattga tatatataga
     6841 atcacttaag ttatatttag tgcataaaca gagcttattt ttaatagtat taaataagaa
     6901 acaatttgta cataattagg gggagtttta atgataatga tggtacttaa taagagtaag
     6961 ctcaaaaaaa tcataatact aattttagta gtgttattag tattatcagg aggggtaatg
     7021 gtattaaagt tatttaacaa caagccagta tttaatttat ttaatggtgt agatttacca
     7081 tatgaaagag gtacaaagga taaaagtgga tatgttgcat taacctgtaa tatagacctt
     7141 ggatgggaaa cagagtacgt agaatccatt ttagaaacac ttaaaaaaga aaatgtaaag
     7201 attacattta atgtaactgg aaaatgggca gaaaagaata aggatgaatt attaaagata
     7261 aaaaaacaag gacatgaaat aggtaatcat ggatacaaac atttagatta ttctacatta
     7321 tcatatgaag acaattatga gcaaatagag acctctaaaa agataattga agaaattata
     7381 ggtgaaaaaa ctaaattttt tcaagcacca gcaggttctt ttggtccaga aacagtaaag
     7441 gctgctaaag cattagggta tacttctatc aaatgggatg ccgatactat agattggaaa
     7501 tacaaagacc aaccagaggt aatcattgat agaatgaaga aaaaagacat taaagatagt
     7561 agtataattt taatgcatcc aaccaacgca acgacaaaat gtatagatga tattatagct
     7621 attgtaagag aaaaaggact aaaaccagga aaacttagtg atgtatttaa gtagacaaag
     7681 tataaatatt tggttaagat tgtataagtt gtagttgaat taattaaaag actgacttat
     7741 aatgtaatac atataaaaaa taaatataat taaaacatag tgttttcaat aatccaatat
     7801 gaaacaaaga ataaattgtt aggagaatgt aatgtataag acaaaaatac tggaaaatgg
     7861 gcttacaata attggtgaag aaataccata tctaaagtca ataacattag gtatttggat
     7921 aaatgcaggc tctaggatag aagaagcaca ggtgagtgga atttctcatt ttatagagca
     7981 tatgatgttt aaaggaacca aaaacagaac atcaaaagag attgctagtt caatagataa
     8041 tttgggtggt caaataaatg catttacaag taaagaatgt acatgttatt atgtaaaact
     8101 aatagatgag catatagata caggaattga tgtattgagt gatatgatac taaattctaa
     8161 atttgataaa aatgatatag ataaggaaag acttataata ttggaagaac ttaagatgta
     8221 tgaagactct ccagatgact tatcttatga tttattagtg gaaaatatat atgctaatga
     8281 tggattagga atgaatataa ttgggacaaa agaatctctg tacaatataa ctagagaatc
     8341 catgttagaa tacttaaata agtattatat tccaaataac gctgttattt ctatagctgg
     8401 aaactttaac tttgatgata tggtggagaa aatcaaatca aaatttggac actgggaaaa
     8461 gaaaaattta agtatagaca taagtgaggc taagtttaat ccttgcttta tatcaaaaaa
     8521 taaagatact gaacaggtga acttagctat gtgcctaaaa ggtattcctt ttgaaaatga
     8581 tgaagaagtc tattcaatgg cagtggtaaa taatattttc ggtggaagta taagctcaag
     8641 gctttttcag aaaataaggg aagaaaaagg tttagtatat tcaatatact catcacagac
     8701 attatatagg aaatgtggtg aattaggtat atttgcaagc atgagtacag aaaatttaca
     8761 agatgtatat aatttaataa agaaagaaat tgaaaatata agagaaaact atcttacaga
     8821 aaaagaaata tctgaaagca aggaacagtt aaaaggaaat tatatattgg atttagaaag
     8881 tactagcagt agaatgatgt ctactggtaa atctatgtta cttagcaaaa aagtaaaaac
     8941 tacagatgaa atacttgaat gtataaataa tgttaatatt aattcaataa agaaggttgt
     9001 tgataaggta ttcaatatcg aaaatattgg tacatgtata gttggaagag atgtagaaaa
     9061 gattctacac ttggattaat attgaaaaaa gtaaatctct ggaggtataa aatatgaatt
     9121 tatctgaaat agcaggtaag gaaatagtta acttggtcac aggagaaaga ttgggggtca
     9181 ttggagaatg tgaccttata ctagatgaaa ctacaggcga tatattagcg cttctaattc
     9241 caaaagaaaa aggatttttt gccagaagaa aagataagtc atttttagaa gtaccatgga
     9301 gaaatgtaaa aaaaataggt aatgacatga taattataga atatgaggga tatatttagg
     9361 aggaaaaaat gagtatttta gtgcaaaagt ttggtgggac atcagtagaa tcatatgaaa
     9421 aaatgaatga agtatgtaag atagtaaaag catacaaaaa aaatgatgaa gaattacaat
     9481 tagtattagt agtttcagca atgggaagaa aaggagctcc atatgctaca gatacactta
     9541 taaatttgtg tagtgcagta aatgatgagc caagtaaaag agaacttgat ttaataatgt
     9601 cttgtggaga aataatatca ggaacaattc ttgctaattt attgaatgca caggggatag
     9661 attctgtttt ctttactggt cagcaagcag gtataattac aagtgatgaa tattctaatg
     9721 caaagataaa gtatataaat cctaaaaagg taaaaagagc tttagatgat ggtaaggttg
     9781 tagttatagc tgggttccag ggtgtaacag atgatggaga aataactact cttggaagag
     9841 gcggaagcga tacatcagca gttgctattg gtaaagcttt agaatgtgaa acagttgaaa
     9901 tttacactga tgtggatggt ataatgactg cagaccctag agtagaacca aacgctaaag
     9961 tattgagttt tatagactat gaggaagtat tccaaatggc tgacaaaggt gcaaaagtaa
    10021 tacatccaag agcagtacag ttggctaaaa gtggaaatat aactttagcc ataaagaata
    10081 caatgaatcc aacttttgaa ggtacaaaaa taggttcttt atgtagacac ttagaagaca
    10141 atatagaata tgaacaagaa agagatttta aggttgctgt tgcaaataaa gatagcgtag
    10201 cacaagttaa gattaagtca gcagaagaag tgtttacaga agtattaaat gagatagaaa
    10261 agaaacttat aactatagat atgataaatt tctttatatc agaaaaagca tttgttgtag
    10321 aagatgctga tataaaatca ttaaaggaaa tactagataa atttgaatta gattatgaag
    10381 taaatagaga ctgtgctaag gtaacattga tatgttcaag aattgctgat gaaatgtctg
    10441 gtatcatgtc aaaggtagtt agaggattat caaaagcagg ggtatctctt ttacaaacat
    10501 cagactcaaa tatgactata tcttgtttag ttagtgaaga agatatgcat acagcagtac
    10561 atgctataca ccaacaattt tatttaaaat aaactgtata atacaattat tttttaatca
    10621 aatttaagaa tttcatatat atcttaatat atttgattta tttggtaaaa ctaaattaaa
    10681 tataattttg ataggagttt ttttatgaaa gattatagag aagataatga aaaatttgat
    10741 aaagataatt gtagtgaaga atctagttgc gaagagagag aatgtataaa gcaatttggt
    10801 accaatgaaa tgccacctca acctcctaaa gatattcaat gtataactat aattggagaa
    10861 attgagggac attttatagg aaatcctcaa aaaaaagcta caaagtacga gcatataatt
    10921 ccaatgctat actcaattga ggaaagtaat gatgttaaag gagtgttagt tgttttaaac
    10981 actgttggag gagatattga agcaggttta gctattgcag aacttttaaa cagtacatct
    11041 aaaaaagtag ttactcttgt tctaggagga agtcatagta taggtgttcc tcttgctaca
    11101 gcaggagatt actcatttat agcaccaaca gcaaccatga ttatacatcc agtgcgaact
    11161 actggtcttg tgattggtat aaatgagact tttgaatatt ttaaaaagat gcaagataga
    11221 ataattcaat ttataataag aacatcaaat atcaaaaaag atgtacttga aaaacttatg
    11281 catgaaaaag atgaacttgt aagtgatgtt ggtagtgtat taataggaaa agaagctgtg
    11341 gattatggtc ttatagatga agttggagga ctaaaagaag cacttaaaaa attaagagag
    11401 cttataaaag aatctgagga agaaaaaaat aatgattaaa atttgtttaa ataataaaat
    11461 ttatgatata atgatgtaat aaagtaggag tgttagtgtt aaggcattag cactttttgc
    11521 tgtgaagggg taaaacttgc taaaaataag gagtgatatt aatggccacg aaaaagaaga
    11581 aaaaaaagaa ggtaaatacc ttaagtttta atgcagaata tcataattta ataacaatat
    11641 ttataggtgt atttttatta tatagtttaa attctaattc tatgggatgg atacctgtgt
    11701 taatgcaaaa tctttttaag ggactatttg gagggctttc aatagcaata ccatttatag
    11761 taattataac aggactttta ggattttttg atggaaatga atatatatat aggctaagaa
    11821 agactaaact atactacata attattttat ttatatttgt attttatgga ttattaaatg
    11881 caggaactct tcctgtagat agcccactaa aaggtaacat gtttgatgat gttatgaaat
    11941 tgggtgtaag tggacaaggt agtggtttga tagcaacaac tattgcgtat tatatgagta
    12001 aaatatttgg tatagcaggt ggatggttaa taagtatctt cgcacttata ctttctgtaa
    12061 tgtttatatt taatatttct ataaaagatt tggtgtcaaa tgcaaaatca aaatctaaag
    12121 catctaaaga cagcaattta acgtttaaag ataaaattgc aaatatgaaa aaatctgcaa
    12181 tagatatgat gactgatgaa gtagatgata ctactataaa taaaaaacca ggtttcttta
    12241 aagggttaat gtcaaaaggt cttaataatg atgatgaaga agatgaatat tttgaagaag
    12301 aaaatagtga tggtgtagat gataaaacta taaaaatagt tggatttaat aaggcagaag
    12361 atgagtattt agaaatatta gaaggaactc aaagtatgcc agagttagat gttttaaaag
    12421 aattacaaaa agctaccaat gaaaatccag ttgtagatac taaaccagaa aaaaaagttg
    12481 atatagctaa acctaattta aatatagaaa aaactcaacc tatgagtatt gtagcagagc
    12541 cagttaatga ggattattca aactataaaa agcctagcat tgagctttta aataaagtaa
    12601 ataagaagtc tgatgaaaat ggtaaaaaga aagtgttgaa aaatgcttct cttttagaaa
    12661 agacactatc agattttgga gtggaagcaa aaattaatca agttacagtt ggacctacta
    12721 taacaagata tgaaatacaa ccaagtccag gagtcaaggt aagtaaaatt gtaaatttaa
    12781 ctgatgatat agctttaagt ttagcagcta aaagtataag aattgaagcc ccaattcctg
    12841 gtaaaagtgc aattggaata gaagttccaa atgaagaagc tcaaatggtt ggtgtgagag
    12901 aagttctaga aagtgaagaa tttaataatt ttaactctcc tcttgcaatg ggacttggaa
    12961 aagacgtagc aggaaaaatt ataattggag atataggtaa gatgccacac ttactaatag
    13021 ctggttctac aggttcagga aagagtgtgt gtgtaaatac attaataagt agtattttat
    13081 ataaggcaaa tcctgatgaa gtaaaattac tattaataga cccaaaagta gttgaacttg
    13141 caaattataa tggaatacca catctattga taccagtagt tactgaccct aaaaaagctg
    13201 caaatgcttt aaattgggca gttacagaga tgaatagaag gtacaaatta tttgcagatg
    13261 ctcaagtaaa agatgtaaca agttataatg agaaagcgga agaaaaactt cctaaaatag
    13321 taataataat agatgagtta gcagatttaa tgatggcaag tgcaaatgat gtagaagatt
    13381 atatttgtag attagctcaa atggcaagag ctgctggaat gcacttgatt gtagcaactc
    13441 aaagaccatc tgttgacgtt ataacagggg taataaaggc taatatacca tctagaatag
    13501 catttgcagt atcatctcaa actgattcaa gaacaatcct tgatatgggt ggtgcagaga
    13561 agcttctagg taaaggtgat atgttattct atccacttgg tgcagcaaaa ccagttagac
    13621 ttcaaggggc attcatatca gagagtgagt cggaaaaagt aatcgatttt gtaaaaagtc
    13681 aggttaaaga tggaataaaa tatgaagaag atataattga aactatatct aaggttaata
    13741 cttcaaaggg tagtgatgag gatgagtttt tgagtgaagc gatagaattt gtcgtggaaa
    13801 gtggtcaagc atctgcctct atgctacaga gaagatttaa aataggattc aatagagcag
    13861 ctagacttat agattctatg gaagaaagag gaataattgg agcaagtgag ggaagtaaac
    13921 cgagaaaggt attaataagc aaacaggatt tgcagaattt agaaggtgaa tagaattgtc
    13981 agttataaaa atagaaaaag cacttaagct agataaagta atatttgtag atgtgagaac
    14041 tgaaggagaa tatgaagaag accatatatt gaatgcaatc aatatgcctc tttttaaaaa
    14101 taatgaacat aatgaagttg gaacaattta taagatgcag ggaaaacatg aagcaataca
    14161 aaaaggattt gactatgtat cgtataaatt aaaggatata tatttacaag cagcagaact
    14221 tgcattaaat tatgataata ttgtcatata ttgtgcaaga ggcggaatga gaagtggcag
    14281 tatagtaaat ttattatcat cattaggtgt aaatgtatat caacttgaag gtggatataa
    14341 ggcttataga aattttgttt tagagtattt aaggcatgta atggatacaa aaaactttgt
    14401 atctgttcat ggattgactg gtacaggaaa gactgatttg ttacatttat tagatgaaaa
    14461 aggaatagac gtgctggatt tagaaggcat agctaaaaac agtggttcta cctttggttt
    14521 tataactttt gataaaaagc caccatctca aaagaacttt gaaacaaaac tatttgaaag
    14581 tatatttttt tcgaaagaga attatatatt tgtcgagagt gaaagcaaac gagttggaag
    14641 tgttacagtt ccaaatgaaa ttttcgaggc aatgacacga gaaggacatc atatattatt
    14701 agaatgtgat attgaaaata gagttgatag actttgtaga gattatattt atgataaaga
    14761 tgaaggtaat atattgattt taaaagaatg tataaacaag tttagaaaaa gattgggtaa
    14821 taaagtagta gatgattata ttgatttatt agaatcaggt gaatataaag aacttgtaaa
    14881 aagatatctt ttagaatact acgacccact ttatatgcat tcagtagaga aatataagta
    14941 tagtaagatt ataaatttta atgatacaca aaaagcttta gaagatgtta tagacttata
    15001 tgagagtata ttggaaggag aaagtgaatg ttaaaaatag cattggaatc attaggatgc
    15061 tcaaaaaatt tagtagatgc agaaataatg atgggaattt taaataacaa aggctataaa
    15121 ttaattggag attttgaaga agctgatgta attatagtaa atacatgtgg gtttatagag
    15181 tcagctaaac aagaatctat agatacgata ataaactttg cagagttaaa aaaaactggc
    15241 aatttgaagt tgttgatagt aacagggtgt ctagcccaaa gatattctga agaattaaaa
    15301 actgaaattc ctgaaataga tgctatagta ggaacaggaa gctatcaaaa tatagataaa
    15361 atacttaaag aattaagtga aatgcatcaa attgtaagcc ttaatgatat agagtttgta
    15421 tttaatgaag atttaccaag atatatatct acacctagct atatggccta tttaaaaatt
    15481 ggagaaggat gttccaataa ttgtacttat tgtataatac caaaactaag aggtaaatat
    15541 agaagtagaa aatttgaaga tataattaaa gaagctaaga aattagctga atctggagta
    15601 aaagaacttg tggttatagc acaggatacg acaaagtatg gttttgattt atatggaaaa
    15661 gaaagattat cagaactttt agaagaactt gcaaaaatag atggatttaa gtggataagg
    15721 gttatgtatt catatccaga atctataaca gaagaattga tacaagttat aaagaaatat
    15781 gataatatat gtagttactt tgatatgcca atacagcatg caagtaacaa tattttaaaa
    15841 ttaatgaata gaaaaactac taaagaagat atattaaata aaatcaatct gataagaagt
    15901 aatataccag atgctatact tagaactaca ataatagtag ggtttcctgg tgaaacagaa
    15961 gatgacttca aacaacttgt ggactttgtt gaagaggtta aatttgatag acttggtgca
    16021 tttgcatatt caagagaaga agatacacca gcagatagat tgccaaacca tatagatgaa
    16081 gaagtaaaaa tacaaagaag agatacttta atgatgattc aacaaaaaat atctgaagaa
    16141 cttaatgaca aaaagatagg aaaaacttat gaggtgttaa tagaagaaca gatagaagat
    16201 aatgtatata caggaagaac acaaggtgat gcagaagaaa ttgacagtat agtgtatgta
    16261 aaaagtgtag acaatcttga agtaggagaa tttgtaagtg ttcaaataaa tgatgcaatg
    16321 gaatacgatt taatgggaga tgttttatat gaacttgcct aacaagttaa ctttgtttag
    16381 aatattttta ataccagtat ttgttttaat tatgttgctc aatgtaccaa ataaattttt
    16441 aatagcttgt attattttta taatagcttc aattactgat gctttagatg gaaaaatagc
    16501 tagaaaatac aatctagtca ctgactttgg aaaatttatg gacccattag cagataagtt
    16561 attggttatt tcagcactta catgtatgat agaagaccat cttgtaagta gttggatggt
    16621 aattataata gtggctagag agcttacagt tagcatatta agagctatag ctgctgctga
    16681 tggaaaagta attgctgctg gaaacagtgg aaaacttaaa acgataactc aaatggtatc
    16741 tatagtgttt ttattgttag gtgctcagtt tgaaaatgta ttgatattaa atattggtga
    16801 aattctcatt cttatagcta cactacttac attatattct ggatgggaat atctatataa
    16861 aaataaagag ctttttatgt cttctaagta aaaaattatg ctttaataaa taaaaactaa
    16921 tgattaataa ataaaaaata acaacttaaa attttaaaaa tgtaaaaaag ggtatactat
    16981 tatagtatac ctcttttcat tttaagaata ttttcttttg tgtatataat tattaataat
    17041 ggtttataaa taaaatgtaa tgaataaaaa tataatcatt agtagcgttt ttaaattgac
    17101 taggtttgat ttatgttata taattaatat ataacaagag aacaaatgtt tgtagataaa
    17161 tgaagggatg gtatagagat gagtgtagat caagaaaaat taaaagcgtt gaatgaagct
    17221 ttaggtaaaa ttgaaaaaga ttttggtaaa ggttcagtaa tgaaattggg agaagcaaca
    17281 tctatgtcta tagatgttat atcaacagga gcgattggtt tagacatagc tattggtata
    17341 ggaggtctac ctagagggag aatagttgaa gtatatggtc cagaatcttc tggtaaaact
    17401 actgttgcgc ttagttgtgt agcatcagct caaaaagatg gaggaatagc tgcatttata
    17461 gatgcagaac atgcacttga cccagtatat gcaaaagctt tgggtgtgga tgttgataac
    17521 ctaataatat ctcaaccaga tacaggtgaa caggctttag agatagcaga ggcattgata
    17581 agaagtggag cgatagatat aatagtaata gactcagtag cagcattagt tccaaaggct
    17641 gaaatagatg gagatatggg tgattctcat gtaggtttac aagctagact tatgtcacaa
    17701 gcacttagaa agttaactgg ttcaattaaa aaatcaaatt gtgttgctat atttataaac
    17761 cagttaagag agaaagtagg aataatgttt ggaaacccgg aaactactac tggaggacgt
    17821 gcactaaaat tctattcatc agttagattg gatgttagaa aaatagatac aataaaacaa
    17881 ggtgataaag ttataggtag tagaactaga gttaaagttg ttaaaaacaa agtagcacca
    17941 ccatttaagc aagctgaatt tgatataatg tatggagaag gaatttcaaa aattggagac
    18001 cttttagata tagctgctga tgtagatata gttaaaaaat caggttcatg gtatagttac
    18061 aatgatacta aacttggaca aggaagagaa aatgttaaaa aattcttgga agataattta
    18121 gatttaacta ctgaaataga tgagaaagtt agagcatttt acaatttaaa tgaagaacat
    18181 gaagaatcag gtatttcagt atcaaaagaa attgtagaag aataagtaaa aatacaaaaa
    18241 aataactagt aattaaagac atgccacgct ccctattagc ttgacacaat gttgaaaaaa
    18301 ttataaaatt aagtgaggat aaaatatcta aatttaattt taattattag gaatattttt
    18361 taatcatagt gatgacattt tgggattatt aacgaaggag gtggatgtca tagatagtgt
    18421 agtaatgatt gtaataggtg cagctgttgg tattatagct ggatattttg ttagaaaaaa
    18481 tatatctgaa gcaaaaattg gacaagctga aaacttggcc aaagaaataa tagataaagc
    18541 acaccacgac tcagaaacag tacaaaaaga aaaattacta gaagctaaag aagagatcca
    18601 taagtggaga acagaagctg aaagagaaaa cagagaaaga agaacagaag tacaaaagta
    18661 tgaaaaaaga gtagtacaaa aagaagaagt cttagataga aaattacaaa atttagaatc
    18721 taaagaagta aacctaagtg aaaaattaaa ggtagtggaa aagaaagaag aagaagttga
    18781 agtaataaaa actcaacagt tagaaaaatt agaaagtata tcaggaatta cttctgataa
    18841 ggccaaagaa atcatcttaa ccaatgcgga gagagatgta agacgtgaaa tgtctataat
    18901 gataaaagag atagaaagtc aagctaaaga agaagctgat aagaaatcaa gagaaattat
    18961 aggatatgca attcaaaaat gtgcagcaga tcacgtagcc gaaactactg taacagtagt
    19021 aagcttgcct aatgatgaaa tgaaaggtag aataataggt agggaaggta gaaatataag
    19081 gactttagaa accttaacag gtatagacct tataatagat gacactccag aagccgtaat
    19141 tttatcagga tttgatccaa taagaagaga aattgcaaga attgctctag aaaaattaat
    19201 agcagatgga agaatacatc cagctagaat tgaagaaatg gttgaaaagg cgagaaaaga
    19261 agttgacaat attataaaag aatatggtga acaagctgca tttgaaacta gtgtacatgg
    19321 gattcatccg gaattaataa gattattagg tagacttaac tatagaacta gttatggaca
    19381 aaatgtactt aaacattcta tagaagttgc tcatatagct ggtataatgg ctgctgaaat
    19441 aggagcagat attagattgg ctaagagggc aggtttatta catgatatag gtaaggctgt
    19501 agaccatgaa atggaaggta cacatgttga aataggtatg gatttactta gacgttataa
    19561 agagtctaaa gaagttatac atgccatgag tactcatcat ggagattacg agcctcaaac
    19621 agtagaggct gtattagtta cagcagcaga tgcaatatca gctgctagac ctggtgcgag
    19681 aagagaaact ttagaagcat atataaagag acttgaaaaa ttagaagaaa tagctaattc
    19741 atatgaaggt gtagaaaaat catttgctat acaagctggt agagaaataa gaataatggt
    19801 aaaaccagaa gctataaatg atgaagaaat acatctattg gctagagata tgactaagaa
    19861 aatagaggat gaacttgaat atcctggaca aataaaagta agcataataa gagaaacaag
    19921 agctatagag tatgcgaagt aaaagaaata atatctaaat aataagaaaa tatttttaga
    19981 aatttaaatt tgccacaaga tatgataata tatcttgtgg cttttaaatt gtttaagttt
    20041 aattttatat aatgcaaaaa taatctaagt gctaaaagtg ctacttacaa aagattaata
    20101 aaataaagct ttatatatgt attatttata taattatcca agtttgtttg atataatgaa
    20161 gttgtaaaat caatacttta ctacaaaata aatagtaaat actacagtaa aatctaaaaa
    20221 taggatataa tagtattaat ataagaagat tataaataaa acctgctaat gaaaatagat
    20281 tatttttagt aggtttttaa attttttata ataaatctta tttttggcta acaagattta
    20341 ttttttttaa gactttactt attattttaa gcattaatta tgaaatttat cattttatta
    20401 tttacagaaa gtattttata acaataaata tctatactta ttgcaaaatt tttttagcag
    20461 ttttgtattt atttgtattt attttgaatt tatttactaa atttgcctat aaaaagtata
    20521 tataaaaata tagttcaaaa tggtataatt aagtataaca gaaggaggta atgtaagtga
    20581 gccaatacat aaatataaat tctcagttag acgccctaaa attgaaggag ttcgagaaaa
    20641 tattttacga aaatatcaat gaggacgtta aagtagtgcc aaaagttact ccttttaaag
    20701 gaataaatac cgatttgttg tatgttaaag atggaagaat tttatttata aaatttatgg
    20761 atacaacaga agatatattt tttattttag aagaagagtt acttgaagtt atgaatgagg
    20821 aatatgaact tttgaaacta aaaatgggac aaaagaatag aaatataagt tataactacg
    20881 tttacattat gccatacgtt gaagttgagg aaacatatga atttgaagaa tttgttaata
    20941 ataatataat agataaaaat aagcttcaag atataatgaa taagggttcg ctggaggaat
    21001 atcttaatga tgagaatgat gaaataaact taaatttatt tttactagac atatgttcag
    21061 aatactatat aataaatgat aaacttcatc taaatgaaaa atttaaaaaa atttcattct
    21121 acaatgatga ctataagtat acagcaacta tgatggaaga cgttcaaatt aaagatgttg
    21181 tttctattaa atatgggaat acacttattg aaggtggttc tggtataggc aaaacagcaa
    21241 ttatgctttc tagggctata aaattagcaa aagtatatcc acatcataaa ttagtcatat
    21301 ttacacatac aaaacaattg tgcaatgagc ttcgagagag gatagagtta ttatacaaag
    21361 ataataacaa tttagaagtt cacacattta gttcttttat atttaaacta gctaaaaaat
    21421 tcaatttaat tgtagattat aacatgttaa aaaatgatta cgaaaagacc tttaataatc
    21481 ttgtaaaaca agcacagaac attataaaaa ataaaaatat gttcaaggct atttttattg
    21541 atgaagcaga aagcttttta gagtatgaaa tagattttat aagggagttt ttatataaaa
    21601 caaaattcat atttaatgtg tgttcttgta actccttgaa tatctctaat agattgaata
    21661 tatttaaaaa attatataat ggtatagaat ttgatgataa gattatctta agtaaaaatt
    21721 atagacaagc taaagagatt gtagatttta caaataaatt ttcaaataat tctaactcat
    21781 atatcaacga attaagacca aatacagaat ttagtacttt cttttatact aaagcactta
    21841 gaggtggaaa taagtctgtt gatataataa aagtaagtga ccttgatgac caaataagtt
    21901 ctgtaatctg ggaaattgag tatttaataa gtaaaaaagg tcttgattat tctgaagttg
    21961 ctatcgttta tccttacaat aagaagaaat taaaaagtgg aaaaaccatt tactttcaat
    22021 atatgttaaa aaaagcattg gaagaggcaa aaattcctta tatatgtgca gaagataatt
    22081 tgacaaatat aagtaagaag gtaggaacta caatagcaaa tatatatgca ataaagaatt
    22141 tagagtataa agcggtaata gtatgtgaat tagagatgtt atacaatcaa actataaatg
    22201 atattgaaca agattatcaa gtaaatgact ttgtaggaga tttaaataag gtttatttag
    22261 ctatgagtag agcaacagac tacctaagta tagtaacaac ttttaatgaa gaagcaagtg
    22321 atataataag acttattaca gaatcaaaag atatttagta aaaaaatatt tgtaatttaa
    22381 gaaaataaaa agagactgag atttgtaaaa taaactttac caattcagtc tcttattttt
    22441 tagtctactt tcccaatatt atcaagaggt aatagtctca ccataacctt accaagaact
    22501 tcatcttcat caaccatacc tacatcaggg aatctactat cattactatt ttctctatta
    22561 tctcccattg caaatagttt accttttgga acaacagtat ctatatctcc agaagtatag
    22621 ttattgtgta tatatggttc atttaataat tttccattta catacacttt agaatttgat
    22681 atttttattc tgtcaccttc agtagctata actcttttta ttaagtcttt tttctttcct
    22741 gtttctccat caactaaatt ggttttaaaa actacaatat cgcctttttc aggtttacca
    22801 accttgtatg atatcctatt taaaatcaga taatctttat catctaaagt aggatacatt
    22861 gattctccac ttacaataga aggtcttata aattgtagaa ttacaaatgc aagtacaata
    22921 gccatagcta ttgacttaat ccaatcaaat atttcttttt taacactcat aacttttctc
    22981 cttatcattt gttattaaat tagaatacat tataatagaa agaaataagc aagaaccact
    23041 atacccaaga ctattctata ataaccaaat actttgaagt catgtttttt gatatagtcc
    23101 ataaaaaatt taataactac aattgaaaca acaaatgcta ctacagaacc aacacctaaa
    23161 ataagccatt caaatccagt aaatccaaat ccagctttta gaagttttaa tgcactagct
    23221 ccaagcattg tagggatggc taagaagaat gaaaactctg ctgctacata tctagaagta
    23281 ccaagtaata ctgcacctat tatagtagaa ccagacctag atgtacctgg tataagagct
    23341 agacactgga ataatcctat acaaagagct aatttatatg taacttgaga aaaatcttta
    23401 tacttaggtt ttttatttct cttttcaagc cctatcatta ttataccata tacaataaga
    23461 gcaatagcaa ctactgttga attaaagaat aatctatcta tatcatcttc aaacagtatt
    23521 ccaataactc cagatggtat aactgcaatt ataaccttaa gccataaacg gactgtttct
    23581 tttttctgct taatattctt tgcgctatca aaaggattta attttctaaa aaatataaca
    23641 agtacagcta atattgaacc aaattgaatt acaactaaaa atgtacttat aaatgtattt
    23701 gaaaaattca attttataaa ctcatcaact aatatcatat gccctgtact acttactggt
    23761 agccattctg ttattccctg aactatgccc aaaatgactg ccttaaaaat ttcaagcaaa
    23821 ctaaatgttt ccaaatcaaa atacctccaa tacaaattta tagtagcata ttttattcat
    23881 agattaataa aaaaatgcca ccttttacta acttataata ccatagtact gtgtagtgca
    23941 caatggaaga ttgatatttt cataaaacct tcacaatata acaaaataaa cttaaaagtt
    24001 atctattgaa taaggggtat atttgagggg gaaatatatg gtatagtaaa agtatagcta
    24061 ttttatttta tgaaaaggaa aggagttatt atgtatagta caaaaatact agatgattat
    24121 gagtatgaaa cttttaatgt tttttctaca aaattaaatc caaacacgaa acacgattat
    24181 ttatcaaagg ttatactgtt taaagaattt ttaaaaggga aagaattgat ttatgctacg
    24241 aaagaagatt gtaaaaattt tgtagactat atacagacta aatatgcgaa atcaacttgt
    24301 gaaaagatat atagttattt acatagtttt tataacttct taaaaaaaga aggatacata
    24361 gatataaatc catttagata tgtagaaaaa cccacagtaa caagaataaa aacaaaagat
    24421 gatgttctaa gtatacaaga aataaataaa cttataggta tcctaccaaa attaaatata
    24481 agagatagag taataatagt ctgtctagtt actactgggt gtttattaaa tgaattagtt
    24541 agcttaaagt ggaaagacct tatggtagat gaaaacgata actcatatgt aaggttaggt
    24601 aagggaagaa aagaaagagt agttaaatta catccatact tttttaaact tttagaagat
    24661 tacaggaatt attctgggct tccagaggta ataataccta gtgatgattt tatttttaca
    24721 actcaaaaga gtaattctat aacagataga aatgtcagac ttatagtcaa aaaagcatta
    24781 gatttagctg gactttctca atattcagca agagatttta gacattcatt tgcagcaata
    24841 agtttaaggc ttggggcaga tgaaagtgat gtaaaaaatc agcttggatg gagtgataaa
    24901 tactatgcaa ttagatataa gtatgtatta aattttgttg atagtgaaat agtggattac
    24961 ttaattgaaa aagataattt ggatataaat aaaaaatagt aataaataaa aaatactata
    25021 tataaatgtg aacaaaaaat aaaaaagtct tgttatagtt cgtaaaatta tatataatta
    25081 tttatgtact aatgtgtaca cagtaatcac acgacaaaag atttaaggaa ggtgctaata
    25141 taatgataga taataaatat actacttact caaacccact tacagacaga tattgtagca
    25201 aggacatgag ttatatattt tctccacaat ttaaattctc tacatggaga aggttatggg
    25261 ttgcacttgc agaaggtgaa catgagttag gaatcaatat aactgaagaa caattagatg
    25321 agctaagagc taatatagat aatataaatt ttgatgaagc tagaaaaata gaaaaagaag
    25381 taagacatga tgtaatgtct cacgtaaaag cttatggttt acaatgtgaa aaagccaaag
    25441 gaataataca tttaggagca acatctgcat atgttggaga taatacagat gttatacaaa
    25501 tgaatgaagc tttaaaactt ctaagagtaa agcttgtaaa tttaataaac aatttaaaag
    25561 aatttgcact taagtacaaa gatatgccag ctcttggatt tacacacttc caagctgctc
    25621 aacttacaac agtaggaaaa agagcttgtt tatgggctca agatttaatt cttgatttgg
    25681 aagatttaaa ctatagaata gacaacatga agttaagagg agttaaaggt actactggta
    25741 ctcaagcaag ttttttaagc ttatttgaag gagaccacga aaaagtaaaa gagttagata
    25801 agaaaatttg taaaaagatg ggataccatt cttcctatgc agtaagtgga cagacatata
    25861 ctagaaagtt agattatcaa gtaataagca tactatcagg gatagctcaa agtatgcata
    25921 agatgactaa tgatataaga cttttacaaa gtttaaaaga attagaagag ccatttgaaa
    25981 aaaatcaaat aggttcatca gcaatggctt ataagaggaa tccaatgaga agtgagagaa
    26041 tagcatcttt atctaagtat ataatctctg aatctataag ccctgcaatg gtacaagcca
    26101 ctcaatggtt agagagaaca ttagatgact cagccaataa gagattggca atacctcaag
    26161 catttatggc agcagatgct atacttgaaa tagggataaa tgtaactgat ggtttagtag
    26221 tatatgaaaa tatgataaat agacgtgtaa atgaagaact tccttttatg gctacagaaa
    26281 caatacttat ggaagctgta aaaagaggtg gagatagaca ggaattacat gaaataataa
    26341 gagaatattc tatgaaagct gcctatagag taaagcatga aggcaaggat aataacttaa
    26401 ttgaacttat aatgaatgat gattcattta aaatgagcaa ggaagaaata ctatctataa
    26461 tggacccaaa aaactttata ggtagagctc cagaacaagt tgtagaattt gtaaatgaag
    26521 ttgtagaacc tgctataaaa gattataagg aagacttagg aaaagtagat gtagacttaa
    26581 gagtatagaa ttgtacagat aaaatataat taaaaacggc tatcttattt ataaataaga
    26641 tagccatttt aatgggctag cgtcttctct ccaccgctgt gaagagttct tctttactta
    26701 ctataccatg aatttaataa aatagctata taaataatat ttaataggaa taatataaat
    26761 aaaaataaaa aaatgataag attactaatt aaatttaaac attcagcaaa aactattgta
    26821 cttgcaatat ttttaatgta aactgaaata aagttattta gataatttaa taaattttaa
    26881 aacaaccgag gtgattatat gaactatata gtaaaagata ccataagttt tttagtaaaa
    26941 acatttccta agatttattc tagcctgtac ttagaagacc taaaaaaatt tgcaccagat
    27001 tataatgtaa ataaaacaca attaagagca ttagttttca taaaaaatta tggagtaata
    27061 agtatgactg atttatgctc taagttaaat atagaaaaag gcagtttaac tagtatggtt
    27121 gatgatttaa ctgataagaa gtatgtaaca aggaaaagag atttagttga tagaagaaaa
    27181 tatctaattg acattactga agagggagat aagatagcaa ctgattttat ggataaatta
    27241 agtgatggtt taggagaaaa actttctaaa ttaactgaag aagacagaaa aaaatattta
    27301 gaagcaataa atactcttca atatatatta aacaaagaag aatttagata gaaaaaatat
    27361 aaaaattttt gtatttaata gtactaagat taattctttg ttattcattt aactatataa
    27421 ttataagtct aaatacaatc taaaaagtac atcttaaatt ttcttgatgt acttttttat
    27481 aatttcttat acattttcgt atttgttagt acgtactcat atctctttgt gtaatttata
    27541 tttttccatt ttatattcaa taattttatt ttctaagctc tttttaaatt tatatatgtt
    27601 acaacgttac tatgtctttg tttgaaaaaa tttacagttt tgaaaaaatt actatttatg
    27661 taaaaatatt ttaaaacaaa ttataaagtt tcaaaaacaa aataaaaata tataattatg
    27721 acatagaaaa cgttttaaaa atttaaaaat ggagggatag aaatgaaaca aaaaatgaaa
    27781 gggttctttt tacagttagg aaaatcattt ttattgccaa tagcattaat atctgcagca
    27841 ggtatatttt taggaataag ttcagcattt tcaaatccta atatagttag tgatatgcct
    27901 tttttagcaa ataattttat tcaaggaata ttgggtttta caaaagctat aacaggagta
    27961 ctttttggaa acttagcaat attctttgct atatcaatat ctgttggtct tgctaaagaa
    28021 gaaaaagcag tttctgcatt ttctggtttt gttggttatt tagtattaca cactagtgta
    28081 aattatatgt tagggtgtag ggggattatt gctgaacctg acatgatgag agaaatgggt
    28141 caagctgtaa ctttaggcat acaaacatta gaattaggag tatttggtgg aattgtagtt
    28201 ggtataataa cagcatcatt acataataaa tactataata taaaactgcc agattattta
    28261 ggattctttg gtggaactag gtttgttcca ataataacaa cagtagtatt ctctattttg
    28321 gggataataa taccatatat atggccatat gtaaatacaa ttattcagag tgtaggtatt
    28381 ggtatagcta gtttaggata tttaggaaca tttgtatttg gatttcttga aagactttta
    28441 ataccatttg gattacatca tatattaaat gctatgttta gatttactga agtaggaggt
    28501 tctttagttg tgggagggca agaagtattt ggagcattga acatattctt agctcaacta
    28561 agtgaccctg aaacaatcag tttttcaaca gaagcaacta gatttttagc tcaagggaaa
    28621 atacctataa tggtatttgg tcttcctgct gctgcatatg ccatgtataa aactgcaaag
    28681 cctgaaaata ggtcgaaggt taaaggtata ttactagctg gtgctttagc aacatttgta
    28741 acaggaatta cggaaccatt ggaattttca ttcttatttg tatcaccaat attatttgtt
    28801 atacatgcat ttttatcagg tatatcattt atgatgatgc atatatttgg agtagcaata
    28861 ggaaatactc aaggtggcat aatagattta gtagtatttg gagttatgca accaaataca
    28921 aagtggattt attctataat acttggttta gtgtatgcaa tagtttatta taatgtattt
    28981 aagattttga tacttagatt taacttacaa actccaggac gagaagaaat aacagatata
    29041 aattttgatt taaaaccttt atcaaataaa gtagaaatag ctcaaagtgg agaaactact
    29101 aagagagcat tatctataat taaatattta ggtggtaagg acaatataga agatataaca
    29161 aactgtataa ctcgcttaag agtagtagtt aaagatatga gtaaagtaga tgaaaatgct
    29221 tttaaaaaat atacaggtgc aatgggagtt ataaaagtat ctgataaaga tatccaaata
    29281 atttatgggc catctgtatc tcaagtaaga gacgaagttt cttttgcaat gtctatttaa
    29341 agtaaatatt aaaaggcaat actaatttat aatttgtatt gtctttttta tagtataata
    29401 aacataagat aaatgctgta tagtgtatat ttatataata aatatgagaa agttgtttaa
    29461 ctacaaatca ttattatgga ggtataaatg aacctaatag acaaattaga tataaatcaa
    29521 aaaaaattat ctacaaatga aatatctctt ttaaactatt ttctaaaaaa ttctgaaaaa
    29581 ataaatcaaa aaaagattaa agatatagca aatgaaactt ttaattcgac tgcatacata
    29641 gtaaggtttt gtcagaagct cggcttttct ggatatagtg aatttaaaaa ctttttagtt
    29701 ttttcatatt caaatagaaa tgaaagaaat aaggagttta ctaaaagtca aagtgatatt
    29761 tttactgatg ttatggatac acaaaattta ataaatgtag agaatataga tatgtgttta
    29821 aatgaaatac ataattctaa gcatatatat ttttttggtg ttgggtcttc tagattagta
    29881 tgtactgaaa tgtctcaacg tttttcagct ataggtgtaa atgtaaaata ctatgatgat
    29941 tcaactctca tgtatttggc tgcatcaaat attactaaag atgaccttgt aattgctgta
    30001 tctatgtctg gagagactgc tcaagttatt aaggcatgta atatagcaaa aacaaatcaa
    30061 gttaaagtaa tttctctgac aaatataagt gtcaattcat tatcaaatat agctgatata
    30121 aaattatttg tatcttctcc acaatataat tttaatagtg ttaactatac atctagagtg
    30181 ccagcacttt ctcttatgga atatatgttt cataaataca ttgaaaaata caatagatga
    30241 aaaaaattac aattttgaaa aaaatactaa aattgaacta tttttaatga ttacctaaaa
    30301 gtattcatgt agaaaacttt atatattata atcatcttac aagttagtta ataaaaaaca
    30361 ggggtgatta atatgacaat gaaaaaaaga tacaatatag ctatagttgg aggaggcagt
    30421 acttggactc caggactttt aaagtcttta tgtaaaatga gtgatagatt tcctctaaat
    30481 aaagtaacta tgttagatgt agtagaagaa cgtcaaagat taatagggga atttggaaaa
    30541 atattattta aagaagaata tcctaaagca acacttgaat atactacaaa cccagatgaa
    30601 gcatttatag atgtagattt tgtatttgtt caaatgagaa ctggtggtct taagatgcga
    30661 gaattagatg aaaagattcc tctacaattt ggactggttg gtcaagaaac ttgtggagct
    30721 ggtggatttg cttatgggtt aaggtctata ggtgatatga tagaaatggt taagactgta
    30781 agaaaatact ctcctaaagc atggatatta aattatacaa atcctgctgc tattgttgca
    30841 gaagcattaa aaagagtatt tccagatgat aaaagattac ttaatatgtg tgaccaacca
    30901 gttaacttgt taaggtctta tggaagattg ttagacatgg attcaagaac atttgagcct
    30961 gtatactttg gattaaatca ctttggatgg tttacacatt tgtatgataa aaatggtgaa
    31021 gatttggtac ctaagataaa agatttagta gcaaactctg gattccaacc tgttgatgca
    31081 gaacaaagag ataaatcttg gttagacact tatggaatgg ttaaagatat gttggaagat
    31141 gtaccagatt acttacctaa tacatatgta cagtattatc tatatcctga taaaaaagta
    31201 gctaaatcaa atataaattg tactagagca agagaagtta tgaatggaag agaaaagcgt
    31261 gtatttgaag aatgtaaatc tgttatagaa aaaggaacat ctataggttc taatttagtg
    31321 cataatgatg ctcatgggga atttatagtt gaagttgcag aagcaatagc tcataacaaa
    31381 caccaaatag ccatagttat aacagaaaat aatggggcta ttagcaactt acctgatgat
    31441 gcaatggtag aagtagctgc gattcttaca aagaatggac cgagaccttt acatgtaggt
    31501 aatataccaa cattttataa gggactgtta gaaggtcaac tagcttatga aaagttagca
    31561 gttgatgcat actttgaaca atcttatgaa aaagctattt tatctttaac attaaataga
    31621 actataatct ctccaactaa ggcaagacaa gttttagatg ctttaattaa agtgaataaa
    31681 gattactggc caacactata taaagaaaat gaaaaatagt caggtctaag tcttaattaa
    31741 tatattaatt aagaaatgtc cccttttcaa ataatatctg aaaaggggac attttatatc
    31801 attaaattta tataaattaa gtttaaaaaa ttatttttgt aaagctacat attgctctaa
    31861 accttctttt aataatgtag cagctctatg aaggtctttt tcatttaaga tgtaagctaa
    31921 tcttatttca tcacgtccta aacctggagt agcatagaat ccttcagcag ggcaaaccat
    31981 aactgtttca ttatctttgt taaattcttt taacatccaa attgtgaaat cttctgcatt
    32041 ttcaactggt aatttagcaa ctatatagaa agcaccagtt ggttttttac atataacacc
    32101 ttcaaccttc attaattcat tgtataatac atctcttctt tttttgtact cttcattaac
    32161 ttctttgaag taagaaacag gagttttgta taactcaaca gctcctattt gctctaatgt
    32221 aggaacacaa agtcttcctt gacataattt aaggatttga gcgataagac ctttattttt
    32281 gcaagcgata gaaccaattc tagcaccaca agcactgtat ctcttagaaa cactgtctat
    32341 tattataact ctatcctgta caccctctaa gttaccacag cttgtatact caagcccatc
    32401 ataaacaaat tctctataaa cttcatctgc tattatccat aaatcttttt ctttagctat
    32461 ttcagctagg atattaagtt cttcttttgt ataaattgca ccagttggat ttcctgggtt
    32521 agaaagaatt atagccttag ttttatcatc tactttagac aatatttctt ctttagatgg
    32581 aaggtggaaa ccgttttctg cctttgttgt aacagcatta acttctacgt ttacagattg
    32641 accaaatcca ttgtagtttg tatagaatgg ttctggaact aatagattat ctcctgggtc
    32701 acaaactgcc atcatagtga aaagtaaagc ttcactacca ccattagtta ctaataattc
    32761 atctttttca aaattcatat cgtaagtttt atagtaattt tgaagtgctt ctaataattc
    32821 tggaatacct tctgatgtag catattctaa gacttcgcta tcaaagtttt taacagcatc
    32881 aaaaaatcct ttaggagttt ttatgtctgg ttgtcctatg tttaagtgat atactttgat
    32941 tcctttatct tttgctgctt gtgcaaatgg aacaagtttt ctgattggag aggcttgcat
    33001 tgcactaact ctgtttgaat aattcatttt aataccccct atttaattta aatacgtata
    33061 ttgtattatg taaattgtat gtttgaatac aagacatctt tacaagataa taataacata
    33121 cttatgggta aaaatcatca aaaaaaatta atatagcttt aaaataaact tttaacaaat
    33181 tatagtaaaa tacccatgtt tatgccacta aattatgtat tcataaatta atttatagta
    33241 agataatatt ctgatatact gatagtgatt ttttagttat aatctttcag ctatagacaa
    33301 aatatataat aata
//
LOCUS       DAMJVG010000043        32640 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.043, whole genome shotgun sequence.
ACCESSION   DAMJVG010000043 DAMJVG010000000
VERSION     DAMJVG010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 32640)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32640)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32640
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.043"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(<1..231)
                     /locus_tag="PC512_002151"
     CDS             complement(<1..231)
                     /locus_tag="PC512_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2441891.1"
                     /translation="MNYNLIKVIFSLFKKKSGYTFTNFLNKVRVEKSKKYILKKDLSI
                     LDVAVLIGFNSQNYYSIIFKKFNNFTPIEYKNI"
     gene            502..693
                     /locus_tag="PC512_002152"
     CDS             502..693
                     /locus_tag="PC512_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441892.1"
                     /translation="MERLMELIERKFLKDVELLELEDIENVIECKMTQPYNAHYNEYL
                     VKVKNGDEVEEYFVYLKHR"
     gene            complement(782..1594)
                     /locus_tag="PC512_002153"
     CDS             complement(782..1594)
                     /locus_tag="PC512_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mrp/NBP35 family ATP-binding protein"
                     /protein_id="HDF2441893.1"
                     /translation="MADCNSCPSKGNCNSQSNCSIENNPNNKFGKIIGVMSGKGGVGK
                     STVTALLANKLNKMGYKVGILDSDITGPSIPRLMGVKNVKAYSDGSYIYPVENSNNIK
                     VMSINLMIDDENEPVVWRGPLLGGVVKQFYTDVLWEELDYLLIDMPPGTGDVALTVMQ
                     SIPISGIVMVSVPQDLVSMIVSKAVNMAKKMNINVLGVIENMSYIQCPDCSKKIKLFE
                     GESTEKFLDDLDLELLGELPMTKEIIDITHNGVTEISDDLDSILTNVVEKIK"
     gene            2016..3167
                     /locus_tag="PC512_002154"
     CDS             2016..3167
                     /locus_tag="PC512_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004452985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2441894.1"
                     /translation="MELRPRSAKLEEFDKVIELINYVFRISRNHKPTMMEEFPLLLSK
                     NNIENMIIISEDDKVVSDVNYLIQDVSIQGNRLKVAAIGGVCTHPDYEKRGYSSKILD
                     KVEEKMFYDGVDIVIISGTRSLYSRRNCSLVKSFYKYTIKPEDVKIAYEIVEFDETNF
                     EKDNDLDKMIELYNQNSTRFIRTRDEFQKLLHAATIAWGPIGYKKVFIKENNNIIGYL
                     IIRTIKKEDSTVGEVAEIGLNSVNVENILKYVANKFGLESLNYKVHVKNLKDQLKCNG
                     TKSLDYQQGTMKIINFTKLCDSLRSYFSQYVDFELLKYMEFKQVENKYIIKYKEEELV
                     IENLDKLNKLFFEKNEEQYNEFKHLKNIYEFATKAFPVDFPWTANLNYQ"
     gene            3285..3923
                     /locus_tag="PC512_002155"
     CDS             3285..3923
                     /locus_tag="PC512_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423639.1"
                     /note="Presence of a B(12) (cobalamin)-binding domain
                     implies dependence on cobalamin itself, in one of its
                     several forms, or in some unusual lineages, dependence on
                     a cobalamin-like analog; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-dependent protein"
                     /protein_id="HDF2441895.1"
                     /translation="MDILDDIAECILNMGVDNIENLVKIAIDKNIDVEDIYEYGLNKG
                     MIGALDKFENKEYYLSEVIVCTDALNKGINLLKGTGKVKKKSKGVILMSVVEGDTHEI
                     GKNIVKVMVEATGYKVIDLGVNRKSEDIIEEAIKNNVDIIGLSSMMTTTMENMKSVID
                     ELNMIEIDKRPKVIIGGGPVSMEFAEEIGADGYSSNAPKAVKLINKLIGGEV"
     gene            3924..4946
                     /locus_tag="PC512_002156"
     CDS             3924..4946
                     /locus_tag="PC512_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase"
                     /protein_id="HDF2441896.1"
                     /translation="MFSDMTLLQYINSEDRGFFLPDMGTNGLFLINKKAYEVYDSVDL
                     QLELAKTMDKYFESDFIYSFCDGITFCETLGLDTLRPDYDFPSVLTHTITDRDKLRKL
                     DVPDPYTSGRMPLNIESLSVISKSIKKPLYESIQGPFTLAGQLAGATQLLRCIITDKK
                     FVEELLEFTTELVRRYAVAANKAGAKYISIAEPTSVTLSKDRFDEFIVKNLNKIYNEL
                     DCWKGMHICGDTRELLDNMLSCNIDAVSLDQILDYEEIAPMIPRDIVLIGNLDPIKLL
                     GRSKPDKIRRETLKLLKKMRRYDNFLCDFGCNCLNTTPVENLQAAIKAGRISYKELDR
                     IDIDEL"
     gene            4936..5556
                     /locus_tag="PC512_002157"
     CDS             4936..5556
                     /locus_tag="PC512_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441897.1"
                     /translation="MNYNSNKNKYLLKDINLDDIFIDKNIVLKFLGYGNRKAPDTISK
                     IVEREIRNINDILDIKIYISEVDINKTPKECKKAFAVLYTIGDKIDFKMNDYMENCNM
                     MAGLALDKVGIVCLDCINEKIKMYLKGKYDSLKISHEIYPGDKDFEVERQKDIYNYVK
                     NKYNSIEIEINDYHQLSPIKSVAMLILMGDEENLESRCSKCPRKCF"
     gene            complement(5680..6366)
                     /locus_tag="PC512_002158"
     CDS             complement(5680..6366)
                     /locus_tag="PC512_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HDF2441898.1"
                     /translation="MKTYKFIFFDADDTLFDFKKSESHAFKKLLSEFDLEFNFENYIE
                     SYRNISDKLWLDLEKNIITLNELKLLRFELFANKISLDVDSETLSKMYLNFLGECTFL
                     IPGAIDILQYLKKKYTIVIITNGISAVQKKRLENSKIKEYIDGMVVSEELKISKPNPE
                     IFKYALKKFNCHDKSSALIIGDSLTSDILGGINSGIDTCWLNSNNSINYTNHIPTYEI
                     NTLIELKKLL"
     gene            complement(6380..6925)
                     /locus_tag="PC512_002159"
     CDS             complement(6380..6925)
                     /locus_tag="PC512_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2441899.1"
                     /translation="MNDLNLGEKIAEVRKKQNLSIRDLAKLADVTPSLLSQIERGLAN
                     PSVNSLKSIASSLNVPLFTFFVSEVDKKNLIVRHDNRKKVILPGSKEVIYEILIPDSS
                     GNLEFAIMDLAPNTSSCVDRITHNGDEIAYVLEGEVKLFMDDDEFTLSKGDSVKVPLG
                     TKHKWQNDSNSESKVIFAVIL"
     gene            7153..8400
                     /locus_tag="PC512_002160"
     CDS             7153..8400
                     /locus_tag="PC512_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HDF2441900.1"
                     /translation="MQITTFGAIFGLLIAIILIIKKFQAVYSLMLGAFIGGLVGGANI
                     TQTVDFMANGAMNISPSILRALASGVLAGSLIKTGAVDKISEQIVKIFGEKRALFSIA
                     ISTMVLAGVGVNLDVSIITVAPIGLYIGRKLNYSKLSILLAMLGGGKAGNIISPNPNT
                     IAVADNFSVNLSSVMMANIIPAIIGVVITVILASILINKGNKVQSYEILEQREDLPSL
                     FKSLCGPIIAIFLLFLGNVSPIVIDPMIALPIGGIVTLIVTGNLNNSREYLAFGLSKM
                     QGVCILLLGTGTIAGIIQMSELQQSTIGALQFLNMPQFLLAPVSGILMSLATASSTAG
                     ATIASSTFHDAIINGGLSPISGASIVNAGSSVFEQLPHGSLFHTSAGSINMDIGERFK
                     LIPYEALIGIVMTIISTSIQLVL"
     gene            8487..10481
                     /locus_tag="PC512_002161"
     CDS             8487..10481
                     /locus_tag="PC512_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HDF2441901.1"
                     /translation="MNKKKIVIIGIIYSFLVVFSLTNMYVNMEYNLNVFEYIKKSLPF
                     TEEEKKWLEKHKNLIYSSDQSSPPLRYKGKEDGQYKGIIVDLINSLSIQIGRDFYFKP
                     NNWWKESFVNSIDDSIKFFDLIPSKERANKFIFTDPIYTLSANILKDKKSQDINSYMD
                     LKGKTVAIPEGDYSINFLKQKIQDINILLTPDIKTGVNHLMSGKVDAVVGDEPVLRYY
                     INNYGLSNKYSVLSNPIYTKKAVLAVPKQYEELVSILNKGIFKLQKNGVYKDLKKKWY
                     STYNEVDDILYERGIVPSIYLFIGIILISIYVFYSYTYLLKIEIKRKTEQVIENKKTL
                     EATFNSITDIIMLVDENNNIVESNKVLYDFMGEMSYKIADLISMIKGVIENTFSENTN
                     KTSEIEIHNKILKINTFPVEYKKNNTEYIVVLIKDITNDKIVEAKLLRENKMISIGQL
                     ASGVAHEIRNPLGIIRNNCYLLKDNVTMEEVNDCVKSIESNVDRASNIITNLLNFARI
                     SDDNLEHINIRNFIENIVKLQYKMLQLKNVEIKIDCEHNLVCYINGESLKHVFINLIS
                     NSIDAIHQDGKIIIYCYEKNYCLFIDFKDNGEGIKEDALKDIFNPFYTTKPIGEGTGL
                     GLYITYNEIKKNNGDISVESKLGVGTCFHIKIPLNKEVTI"
     gene            10481..11803
                     /locus_tag="PC512_002162"
     CDS             10481..11803
                     /locus_tag="PC512_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent Fis family transcriptional
                     regulator"
                     /protein_id="HDF2441902.1"
                     /translation="MKILLVDDELEYGVVMKKILQKKGYLVDIALSGEEAINIIKKDK
                     NYDLVLSDVMMKNMDGVQLLDRIKSINRDIEVILVTGYGSIENAVDAMKRGALSYFIK
                     SNPIENLLEEVEKVKASKISVSVQKNNLEFTLESKNRDFNNIIKIAKKAACKDVNILI
                     LGESGVGKDILARYIHSISPRKNEIFVPVNCCSFSENLLESELFGHEKGSFTGAVDSR
                     KGRFELSNKGTLFLDEIGDIPLNVQVKLLRTLEDKSIERIGSNKSIKVDFRLICAMNK
                     EPKVEISNGNIREDFFYRISTITITIPPLRKRREDLTTLIEFFLNKYQIEHDKKIHSI
                     DKEVKDFLLNYNYPGNIRELKNIINRLVVLSEEGNLSKDNLNLISNNVYIDDKISIRP
                     LREIRKEFECEYIEKVLSLCGNNISNTAKKLEISRRQLTNKISEYNIK"
     gene            12082..13368
                     /locus_tag="PC512_002163"
     CDS             12082..13368
                     /locus_tag="PC512_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006807454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase component B
                     subunit"
                     /protein_id="HDF2441903.1"
                     /translation="MKLELGNIFIKNVEFGEKTEVKDGVLYISSEEIEKIVLEDERIV
                     SVNVELARPGESIRIAPVKDVIEPRVKIGDESKIFPGIINKVKTVGSGRTHVLLGACV
                     VTCGNIVGFQEGVIDMSGPTAKYTPFSKTNNICIVIKAKDGIDTHDYEEAARIAGLKI
                     GAYVGEAGREVEPDEVIVYETKPLLKQVKEYPDLPTVAYVHMLQSQGLLHDTYYYGVD
                     AKQIVPTFMYPTEIMDGAIISGNCVAPCDKVTTFHHLNNPVIHDLYKRHGKDLNFIGV
                     ILTNENVFLVDKERSSDMVAKLIEFLGVDGVLVTEEGYGNPDTDLMMNCRKCSEVGAN
                     VVLITDEFPGKDGKSQSIADATKEADAVVSCGQGNLVVHFPAMEKIIGTLDYVEMMIG
                     GYKGCLNEDGSMDAELQIIIASTIANGYNHLTARYY"
     gene            13454..14761
                     /gene="grdB"
                     /locus_tag="PC512_002164"
     CDS             13454..14761
                     /gene="grdB"
                     /locus_tag="PC512_002164"
                     /EC_number="1.21.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:14501..14503,aa:Sec)
                     /transl_table=11
                     /product="glycine reductase complex selenoprotein B"
                     /protein_id="HDF2441904.1"
                     /translation="MSKIRVVHYINNFFAGIGGEEKADIPPEKRAGVVGPGIAFQSQF
                     NDDAEIISTVICGDTYFGENIESATQELLKMIKEESPDLFIAGPAFNAGRYGVACGTI
                     CKAVEEELNIPVITGMYKENPGVDMFKLDLHIVSTGNSAASLRKVVPIMTKLGLKLVR
                     GEEIGPPEEEGYIMRGIRKNFFHELRGSERAIDMLVKKMKGESFETEYPMPEFDRVTP
                     MKPVKDLSKIKLALVTSGGIVPIDNPDKIESSSATKYGIYDLTDMDSMSNKEFTTIHG
                     GYDRAYVLENPNLVVPLDVVRELEKEGVIGELVDYFITTTGTGTSVGNSKRFGEEFSK
                     KLLEDDVDAVILTSTUGTCTRCGATMVKEIERAGIAVVHICTVVPISLTIGANRIVPA
                     VGIPYPLGNPMLGEEESKKIRKNIVLKALNALTEDIEEQTVFE"
     gene            15039..15770
                     /locus_tag="PC512_002165"
     CDS             15039..15770
                     /locus_tag="PC512_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2441905.1"
                     /translation="MIRKKVYILISIAICDDESYMLNHLKENIELYMKQKNLLYNIEL
                     FNKVEDLLCNHEKFNIVFLDIQMEEINGMQAARKLRSYGNECFIIFVTVLNEFVFDAF
                     EVDAINYLIKPLSNEKLYKTLDKIVTKLDDNESNYITIQKGYSYWKLKLADILYCEVI
                     KRKIYVHLKKETVDYYETIENLERSLPTNFFRCHRSYIINLQYVYGYENGNAVMESGD
                     RIPVSRLRQQIFSKVMLEFMKNRRI"
     gene            15772..17130
                     /locus_tag="PC512_002166"
     CDS             15772..17130
                     /locus_tag="PC512_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDF2441906.1"
                     /translation="MINLFSSDLFLKYSFLFSFIVYRILMVIVQYYFLISFTNVNSKF
                     WCFILYSIISIFLIIINTYFNLYNLFSSQILFFLMTFLFVKYIIKQSTVLSIVSTLLV
                     YLIEQLVYGFTAPLNYLIFTSDINTDIYKFDINMGLSSLITIIIAGFIYWYSSKKFNI
                     KVMNFDKYIAILMIPLLLIILFMQSFEYSSNINIDTSLGIVKLLLNTSITEEIQAFLF
                     SIIGTICVFFSLFTFKKLIQALEDDKERAIMNQQIHAQKNYIEEAKSRLSQTISFRHD
                     FNNHLAIVNGLLKKDQILKAQDYLNKLEKVTSDLSFSCNTQNIVIDALFNNKLSIAKQ
                     LGIEVDCEVIIPQSTNMNDFDLCIVFANAIDNAIKACRVVDKQNRYLKLSTKLEGGFF
                     MIEIKNSYNPINNYTSGSGIGLLNIKEIAKKYQGAISIDKTSDYFQINVLLVISLHCA
                     SI"
     gene            17169..17654
                     /locus_tag="PC512_002167"
     CDS             17169..17654
                     /locus_tag="PC512_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441907.1"
                     /translation="MYLNRESLIYRNEEVTKMKVGNINGQAPITNGLDSCQSEVQGLE
                     QKKKSLQDEIEKVRSDKSIDGETAKLKIEALKKEMEEIENKIQELKGNKAKKTNKEEN
                     NVSEVNNNLLERKKEPSNNENVKQLYDVFERSNVDEQWDNTYRVLQDDKNLKVKFNRP
                     I"
     gene            complement(17917..18153)
                     /locus_tag="PC512_002168"
     CDS             complement(17917..18153)
                     /locus_tag="PC512_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441908.1"
                     /translation="MLLTHIYFNGQFKQTIELYKQAFNATVKTLIEDSCYLLIVHNEI
                     VIHNKFLILNDFGNKNGVSISEGYQPTDKIQTAS"
     gene            complement(18308..18532)
                     /locus_tag="PC512_002169"
     CDS             complement(18308..18532)
                     /locus_tag="PC512_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HDF2441909.1"
                     /translation="MTVYNLKLGQKGIIDNIAGNEKLMKRLLALGLIDGTEVEVKKIA
                     PLNDPIVIRFRGFDLAIRKSDAKNINLKNN"
     gene            complement(18629..19882)
                     /locus_tag="PC512_002170"
     CDS             complement(18629..19882)
                     /locus_tag="PC512_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:glutamate symporter"
                     /protein_id="HDF2441910.1"
                     /translation="MITLSFDIVQTLTLSIFFFLIGNLLKNKVNFLNNFCIPAPVIGG
                     LLFCFLNLFFKYFNIADISISGNLMPNFITFFFTTIGLEISINLIKKGGSVLFRYWIL
                     CGVLAFCQNILAITISKIIKLEPLLGLMCGNVSMEGGHGYSAAFGLTIENLGIEGAVG
                     VGLSAATIGLIMGGILGCPVAKFLINKYKLKPSSNIDLSIPRYNRNLKRFGSKFFRNK
                     NRIKNNNFSETITPSVFLEQVLLIFICINTGEIISRCFYITFNILLPSVVTCMFSAVI
                     FRNLNDKINILELNFKLIDFLKELSLGIFLTLSLMNIDLFELSTLLPPILLIVTFQVI
                     FIILFSIFICFRVLGKDFDSAIIISGLIGHGIGATPNALANMSSLTQKYGDSPKAFLV
                     VPLVSGFLLDAISIPCILFFINILT"
     gene            20142..21131
                     /locus_tag="PC512_002171"
     CDS             20142..21131
                     /locus_tag="PC512_002171"
                     /EC_number="3.5.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HDF2441911.1"
                     /translation="MFENLPKIDLHCHLDGSVRVETMLDIAIKEKIDLPSNNMDEIKK
                     LAKVSFNCTSLDEYLEKFDLPLKVMQSKENLKRITFELLEDASRENVKYIEIRFAPLL
                     HTQKGMSVKNIIEGIIEGIREAESIYDIKGNLILGCMRTMTSKEALLVIEEGKSFVNK
                     GVVAVDLCGPEKEGFCKEYKDVFKLAREYGYKVTIHAGEAASGENVLDAINILKADRI
                     GHGVKIKDHKKAYNLVKDKKILLELCPTSNVQTKTVDSYEAHPFYTFYKDNLHVSINT
                     DNRTVSDINLSSELNVIFDTFKLGLEDYKIIYRNAVEASFADKETKEYLNSLI"
     gene            21203..21943
                     /locus_tag="PC512_002172"
     CDS             21203..21943
                     /locus_tag="PC512_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EcsC family protein"
                     /protein_id="HDF2441912.1"
                     /translation="MKDYEDVVYIKLVKKELEEWKKNILKKPSIFDKASKGIQNKFNG
                     VLPDKYHEIITSSIKVMTKTVLFGYKYATKPPLRNMSLEEREKLVLEKAKTYKTTAMI
                     EGAGTGAGGILLGLSDFPLLLGIKVKFLYDVASIYGYDVKDYRERIYILNILQLAFSS
                     QQHINKTFKLMNNWDEYVNSLPEDINDFDWRTFQQEYRDYLDLAKFLQLMPGIGAFVG
                     FYVNGKLIDKLCETAVSAYRLRIRELKL"
     gene            22159..23310
                     /locus_tag="PC512_002173"
     CDS             22159..23310
                     /locus_tag="PC512_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacyl-CoA dehydratase"
                     /protein_id="HDF2441913.1"
                     /translation="MTNLPKQFDSFNEARQKGFINAKELKESGKKMVGVFCTFTPVEI
                     PMAAGATVVGVCGVSEEPIPDAERVLPRNLCPLIKSSYGHAITDTCPYFYFSDLLIGE
                     TTCDGKKKMYEELAKVKPTYVMHLPNTSKGEFAYKLWKDEMIRLKEEVEKSLGVTITE
                     EDIRTAIKDKNEERELLKEFYALGKLQPSALTGLELHNVLYQAGFKFDRAELKHSLRK
                     VIDDMKERYEKGECPVQKDKPRILITGSPIGGISEKIVKTLEDAGASVVAYELCGAIR
                     SNDLLVDEEIEDVYDALTQKYINIGCSCMMNNDNRIELLDRIIDEYNVDAVIDVVLQA
                     CHTFNIESYRIREFVTKEKNKPFMSLETDYSKSDTEQLRTRFEAFVEML"
     gene            23335..24090
                     /locus_tag="PC512_002174"
     CDS             23335..24090
                     /locus_tag="PC512_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyglutaryl-CoA dehydratase"
                     /protein_id="HDF2441914.1"
                     /translation="MFSIGVDSGSVATKGVLFDGEKIIKKIIIPTGWSPKSTSKQVYE
                     LLSSEIDKKDIKKVVGTGYGRGVMDFADKKVTEITCHTRGIYFLNKNIRTILDVGGQD
                     SKVINLDRDGNVFNFIMNDKCAAGTGRFLEITSNLLGSDIESIDTLAKGYEPVNISSM
                     CTVFAESEIVSLLAQNISTGEVAAGILKSIANKSTSMLARGEVIDEVAFTGGLAKSKE
                     LVKMIEEILGKKIFIAEDTQIIGALGAAVIGFR"
     gene            24282..26669
                     /locus_tag="PC512_002175"
     CDS             24282..26669
                     /locus_tag="PC512_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding cysteine protease Cwp13"
                     /protein_id="HDF2441915.1"
                     /translation="MKKFTSKKVTRFVALFLISILVMSTIPVSADNSNTLNQIKKAEY
                     SETYKQYLNDAKNGCTEKYNGIIPNPYQLEGTQIQSKGRTAPTSYDPRKLGLMTSIKN
                     QEDLGICWDFAAMATLESFLKLNNYGDYDLSEEHLRWWASDGEYGWSVNDMNGALNYE
                     AMGYLTSWSGPKLEKDIPYNGRVSKAQGAKKPTNMNTAPTVFNVTDAVCVSNDINSTK
                     NAILQYGAVTSGYYEDIKYQSDDQNSYYCPTKSFNTNHAISIVGWDDNYSKDNFNANI
                     RPSKNGAWLIKNSWGDYNSEGGYFWISYEDKTLMSDIDNFSIKGGKKPNDDEKMYQHD
                     YASIVPLISKKITAANVFDFNRGDETLKSVMFLTESIGAKYEVYYAPVVNGIPQENNM
                     KKLKEGTAQYSGYITVPIDSFDIPEGKGAIVVSIEGKNGESTIGSESNVPGYDTFKAK
                     ANLGESYIIDNTGKFFDINRDSNFYPCNFTIKAVTEKSSGESIPNESLIGSDRYETAI
                     KVSQNGFNSSENVVLVNGSSIVDALAATPFTSAINSPILLTQKEALNSKTKAEIQRLG
                     AKKVYLIGGENSISKEIEQQLKSLNISIERISGSDRYKTSLLLAQKLNGIKNVSQIAV
                     VNGVKGLADAISVGAAAAENNIPIILANEKSELQGADEFLNSLNIEKSYIIGGTASLS
                     NNLESKLKNPTRLSGSSRDETNSKIIDNFYKKDTLKNAFVVKNGIKNQNDLIDGLAVG
                     PLGAKTGSPVILVGDKLADSQKEVLKNKTLEKVTQVGGGANKNAFKELVKLKSAK"
     gene            complement(26900..27133)
                     /locus_tag="PC512_002176"
     CDS             complement(26900..27133)
                     /locus_tag="PC512_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HDF2441916.1"
                     /translation="MATTTKNRFYDYVQENLNKYVEVHSYFSSCPLYGEIIEADSLSI
                     TLCSRYIDESNPTLNETYTLYLPLSSIISIRTL"
     gene            27422..28012
                     /locus_tag="PC512_002177"
     CDS             27422..28012
                     /locus_tag="PC512_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2441917.1"
                     /translation="MPKSYSDKEREYIIKRLKEEARLCMEQYGIRKTTVDELVKRVKI
                     PKGTFYLFFQSKELLFFEVLRDIHDSIQKEILYEINRVDESITCEQLTDIFMKFYRMV
                     DSTSILNLMINGEFEILVRKLPDSIIEEYFRHDDFEIGEIISCIPNAKNKDIESFSGA
                     FRAVFLTMLYKREVGSNCFEDALRLMINGLVIQLME"
     gene            28126..28971
                     /locus_tag="PC512_002178"
     CDS             28126..28971
                     /locus_tag="PC512_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2441918.1"
                     /translation="MIKVDDLSFSYTDRDFLQNINFEVGKGEILGFLGPSGAGKSTLQ
                     KILIGMITNYGGSVIVNGVESKRHSNKFYENIGVDFEFPSLYEKLTAIENLKYFGSLY
                     SKKLLSIDELLKSVGLENESNKRVSEYSKGMKSRLNFIKALLHNPDILFLDEPTSGLD
                     PSNSKVMKDIILSEKSKGKTIILTTHNMLDATELCDRVAFIVNGKISALDTPHNLIMS
                     KGAIKVRYTYFDNGEKTSECFLNNTANDKNLNMLIEKNKLLSIHSSEPTLNDIFIEIT
                     GRNLQ"
     gene            28968..29651
                     /locus_tag="PC512_002179"
     CDS             28968..29651
                     /locus_tag="PC512_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2441919.1"
                     /translation="MRLKNLILGDIKFQFKYGFYFLYLFLSIIYICIINVFPTFMREK
                     IAIIMIYSDPAAMGLFFMGAIVLLEKSQRVLNSLAVSPVKVSEYILSKVISLGVISSI
                     VAMFIAITLNLDNIIISTIGTFFSSIIFSLLGLIIASKASSLNQFIVLSIPIEIICFI
                     PPILNVLLDTKSYANLYPFNICISLISGDKNFIMINILILISIIIIIYFITYYFICSS
                     WKKVGGVKL"
     gene            29648..30364
                     /locus_tag="PC512_002180"
     CDS             29648..30364
                     /locus_tag="PC512_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2441920.1"
                     /translation="MIKIINAFKQEFEQIKRDAMLFIVCVSPILCGVFIKFGIPLIQN
                     ISLNKFYYQLNLEPYFLMFDLLLAFITPFMFFFASTMVILGEIDDSISRYLIVTPLGK
                     TGYLISRFGIPGILAFIITMILLIFFSLTKISLLLNLSISLLVLLQGVIISILVISLS
                     SNKLEGMVITKFSGVFMMGILAPFFILNKAQYILFFLPTFWISKAFKEDNYVYMFISI
                     VISLIWILLLFKKFSKKIVK"
     gene            30461..30724
                     /locus_tag="PC512_002181"
     CDS             30461..30724
                     /locus_tag="PC512_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2441921.1"
                     /translation="MKNKIKILREKLGLTQEQLGRLVGTSRQAINAIETGKNEPSIWL
                     AYDISRIFNEPIESVFLFEESERKSRAQISRGEYYGYKKDKNI"
     gene            30696..31151
                     /gene="def"
                     /locus_tag="PC512_002182"
     CDS             30696..31151
                     /gene="def"
                     /locus_tag="PC512_002182"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HDF2441922.1"
                     /translation="MAIRKIRTFDDEILRKKSKYVENVDNKIREILNDMAETMYNTPN
                     GGGLAACQVGVLKRLVVIDLGEGLIKLVNPEIIEQEGEQIVVEGCLSFPEVWGKLKRP
                     KKVTVQALNEYGEKIEIKGSGFMAKCLCHEIDHLNGIVFTDKIIEHVKL"
     gene            31203..31664
                     /locus_tag="PC512_002183"
     CDS             31203..31664
                     /locus_tag="PC512_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine dimer DNA glycosylase/endonuclease V"
                     /protein_id="HDF2441923.1"
                     /translation="MRLWHKDLIDVLPKNQLVSQWRELLAIKGSIDKKGTPNHLLVNK
                     VLNYSIDEFKFYTKIVHDEMLKRNYKPNELKYTSILKWKNRNFANDISNEHSLNLENL
                     YDDWHNKMYLKQCLYNLEEKATCGGIPINEWNILLCKYSKDYELWSGNIMF"
     gene            31714..32616
                     /locus_tag="PC512_002184"
     CDS             31714..32616
                     /locus_tag="PC512_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF2441924.1"
                     /translation="MYNKIKYIPINCEIACNKLKRSMPYKWDLNIYRGCEHGCKYCYA
                     IYSHKYINSNNYFEEIYVKTNIVEKLERQLKSSKWKKEVINIGGVTDSYQPIEADYKI
                     MPEILNLLIKYKTPAIISTKSDLILRDYDLIDKLSRITYINVASTITTVNEDTQRLIE
                     PNGVDSMRRFKMLKEFRKTNASVGLHIMPIIPYITDDFDNINSLFRHAKECNVHYVLP
                     GTLYLRGITRGVFFDFVKKEFPELFDKLSILYSAGSLNREYKNQLYKMVNELRYKYSL
                     SSSYSKIMKEKLKNSGDVQISFFD"
BASE COUNT        12985 a         3418 c         5345 g        10892 t
ORIGIN      
        1 aatattttta tattcaattg gtgtaaagtt attaaacttt ttaaaaatta tactatagta
       61 attttgacta ttgaatccaa ttagtacagc aacgtctaaa atagacaagt ctttttttaa
      121 tatatacttt ttgctttttt caactctaac tttatttaaa aaattagtaa aagtatatcc
      181 actttttttc ttaaacaaag aaaaaataac ttttattaag ttgtaattca ttacatatat
      241 tacttactgt tatatcttct gagtaatttt tgtgaatata atttatagtt ttctttaagt
      301 tttctttaca taaaactaag agttggtcta tgtttcattt tatcaaggca tatttattaa
      361 aaaatcaatc tctatttgtt aaaataattt atgaatgatg ttagaaactg taatatattg
      421 gatataatat aataaacaga taaactctgc attaagagga tatatagttt atcttaatta
      481 taggggaagt gaggatatat tatggaaaga ttaatggaac tcatagaaag aaaattttta
      541 aaggatgtag aacttttaga attagaagac atagaaaatg taatagaatg caaaatgaca
      601 cagccatata atgctcatta taatgaatat ttagtaaaag taaaaaatgg agatgaagta
      661 gaagaatatt ttgtgtattt aaaacataga taaacataaa agaggtttat atttatttgt
      721 atgattataa aataaataca agcctctttt tttgataaat ataaaattat aaaattttta
      781 tttatttaat tttttcaaca acattagtca atattgaatc taaatcatca ctaatttctg
      841 taactccatt atgagtaata tctataattt ctttagtcat aggaagttct cctaaaagct
      901 ctaagtctaa atcatctaaa aacttttcag tagattctcc ttcaaataac ttgatttttt
      961 tagaacaatc aggacattgg atataactca tattttcaat aactccaagg acatttatgt
     1021 tcattttttt agccatatta acagcttttg atacaatcat agataccaaa tcttgaggta
     1081 ctgaaaccat aactattcca cttataggaa tagattgcat aactgttaag gcaacatctc
     1141 cagtaccagg aggcatatct attaataaat agtctaattc ttcccaaagt acatcagtat
     1201 aaaattgctt tacaacccct ccaagtaaag gtcctctcca aacaacaggt tcattttcat
     1261 catctatcat aaggtttata gacattactt ttatgttatt tgagttttct acagggtaaa
     1321 tataagagcc atcagaataa gcttttacat tttttacacc cataagtcta ggaatacttg
     1381 gtccagttat atctgagtct aatataccaa ccttatatcc cattttgttt agcttattag
     1441 caagtaaagc agttacagtt gattttccaa ctccaccctt cccactcata acaccaatta
     1501 tttttccaaa tttattgtta gggttatttt caatagaaca atttgattga ctattacaat
     1561 ttccctttga tggacatgaa ttacaatctg ccatatctat tacctccaaa ctttaatatt
     1621 tattagatta tttgtaacct acatatacta ttttagtaca attgaaccat aaagtcatta
     1681 tttaaaagca acttagaaga ttttctattg atttattcat agactatagc aaaaagaata
     1741 caataaaaaa attataacat tcttgaaaaa gtgattattt caatttagtt atagaactta
     1801 gtcatataaa tatatagaaa atattttaat atattataca taacgggtta ttttataagt
     1861 ttaactataa attaggttta tattttataa aaatttgcta aaaaaaacaa ttaaaaattg
     1921 taaagaaaaa agatataatt agaactgtag taataaatgt tttattatag ataatagagt
     1981 tttaagtatc ttaaataata tttggaggaa tatgaatgga attaagacca agaagtgcaa
     2041 aattagaaga atttgataaa gtaatagaat taataaacta tgtatttaga atatcaagaa
     2101 atcataaacc aactatgatg gaagaatttc ctcttttact aagtaaaaat aatatagaaa
     2161 atatgattat aatatcagaa gatgataaag tggtttctga tgtaaactat ctaattcagg
     2221 atgtatctat tcaaggaaac agattgaagg ttgcagctat aggtggagta tgtactcatc
     2281 cagattatga aaagagaggc tattcatcta agatattgga taaagtagaa gaaaaaatgt
     2341 tttatgatgg tgtagatatt gtaattatat caggaacaag aagtctatac agtagaagaa
     2401 attgtagttt ggtaaagagt ttttataaat atacaataaa acctgaagat gtaaaaatag
     2461 catatgaaat agttgaattt gatgaaacta attttgaaaa agataatgat ttagataaaa
     2521 tgattgaact atataatcaa aatagtacta gatttataag aacgagagat gagtttcaaa
     2581 aactattgca tgcagcaact attgcctggg gaccaattgg ttacaagaag gtatttataa
     2641 aggaaaataa taatataata ggatatttga taataagaac aataaaaaaa gaagattcta
     2701 ctgtaggaga agttgctgaa atagggttaa actctgtaaa tgttgaaaat atattgaaat
     2761 atgttgcaaa taaatttgga ttagaatctt taaattataa agtacatgtg aaaaatctta
     2821 aagaccagtt gaaatgtaat gggacaaaat ctttggatta tcaacaagga actatgaaaa
     2881 taataaattt tactaagttg tgtgatagtt taagaagtta ttttagtcaa tatgtagatt
     2941 ttgaattact aaaatacatg gaatttaaac aagttgaaaa taaatatatt attaaataca
     3001 aagaagaaga acttgtaata gaaaatttgg ataagcttaa taaactgttt tttgaaaaaa
     3061 atgaggaaca gtacaatgaa tttaaacatc taaaaaatat atatgaattt gctacaaagg
     3121 catttcctgt agattttcca tggactgcaa atttaaatta tcaatagttt tagatgatat
     3181 taaataaaat tgattgatac ctagagttag tccttgttaa ataagagaaa ttattggata
     3241 ttgaaaaagc aattttgtaa gtaattagaa aggatgagta ttatatggac atacttgatg
     3301 atatagcaga atgtatatta aatatgggtg tagataatat agagaattta gtaaaaattg
     3361 ctatagataa aaatattgat gtggaagata tttatgaata tggtttaaac aaaggtatga
     3421 taggagcttt agataagttt gagaataagg aatactatct ttcagaagtt atagtatgca
     3481 cagatgcatt aaataaaggt attaatcttt tgaagggaac tggaaaagta aagaaaaaat
     3541 caaagggagt aattctgatg tctgtagtag aaggagatac tcatgagata ggaaaaaata
     3601 ttgtaaaagt aatggtagaa gccactggat ataaggttat tgacttaggt gtaaatagaa
     3661 aaagtgaaga tataatagaa gaagctataa aaaacaatgt agatataata ggcttatctt
     3721 caatgatgac aactacaatg gaaaatatga aatcggttat agacgaactt aatatgattg
     3781 agatagataa aagaccaaaa gtaataattg gtggaggacc tgtaagtatg gagtttgcag
     3841 aagaaatagg agcagatgga tacagttcaa atgctccaaa agcagttaaa ttaataaata
     3901 aacttatagg aggtgaagtt taaatgtttt cagatatgac tttacttcag tatataaata
     3961 gtgaagatag aggttttttt ctgcctgata tgggtacaaa tggattgttc ttaataaata
     4021 aaaaggcata tgaagtatat gatagtgtag atttgcaatt agaattagca aagactatgg
     4081 acaagtattt tgaatcagat tttatatact cattctgtga tgggattaca ttttgtgaaa
     4141 ctctgggttt agatacatta agaccagatt atgattttcc aagtgtattg acacatacta
     4201 taactgacag agataaatta agaaaattag atgttccaga cccttatacg agtggacgta
     4261 tgccactcaa tatagagagc ttatcagtta tatcaaaaag tattaaaaaa ccactatatg
     4321 aatcgataca aggtccattt acacttgcag gtcaattagc tggagctact caacttttaa
     4381 gatgtataat aactgataaa aaatttgtag aagaattatt ggaatttaca actgaattgg
     4441 taagaagata tgctgtagct gcaaataaag caggagcaaa atatatttca atagcagagc
     4501 caacatcagt aaccctaagt aaagatagat ttgatgaatt tatagtaaaa aatttaaata
     4561 aaatctacaa tgaacttgat tgttggaaag gtatgcatat atgtggagac accagagaat
     4621 tattagataa tatgctaagt tgtaatatag atgcagtaag tttagaccaa attttagact
     4681 atgaagaaat tgctccaatg attcctagag atatagtttt gattggtaat ttagacccaa
     4741 taaaacttct tggacgttct aagccagata agattagaag agagacacta aaattgttaa
     4801 agaagatgag aagatatgat aactttttat gtgattttgg ctgtaactgc ttaaatacca
     4861 ctccagtaga aaatttacaa gcagctataa aggcaggaag aattagttat aaagaattag
     4921 ataggattga tattgatgaa ttataatagt aataaaaata aatatctttt aaaggatata
     4981 aatttagatg atatttttat agataagaat attgtgctaa agtttttggg gtatggaaat
     5041 agaaaagctc cagatacaat tagtaaaatc gttgaaagag aaataagaaa tataaatgat
     5101 attttagata tcaagatata tataagtgaa gttgatatta ataaaacacc taaagaatgt
     5161 aaaaaagcat ttgctgtact atatacaata ggggataaaa ttgattttaa gatgaatgac
     5221 tatatggaaa attgcaatat gatggcaggg ctggcattgg ataaggtagg tatagtatgt
     5281 ttagattgta ttaatgagaa aataaaaatg tatttaaaag gaaagtatga tagtctcaaa
     5341 atatcgcatg aaatatatcc aggagataaa gattttgaag tagagagaca aaaggatatt
     5401 tataactatg taaaaaataa atataatagt atagaaatag aaattaatga ttatcatcaa
     5461 ctatccccca taaaaagtgt tgcaatgctt attttaatgg gggatgaaga aaatttagaa
     5521 tcaagatgta gtaagtgtcc tagaaaatgc ttttagttaa ttttcaagac taagatttgt
     5581 tttgtgtata aattgcaata atttttttgg tcattttatg tataaactaa aaaaattatt
     5641 gcaaagtaat attctattta atttgaacag acttacaaac tatagtagtt tctttaattc
     5701 aataagtgta tttatttcat aagttggtat atgattagta taatttatac tgttattgga
     5761 atttaaccaa caagtatcta ttcctgaatt tattccacct aagatatcag aggttaagct
     5821 atccccaatt attaaggcag aagatttatc atgacaatta aactttttga gagcgtattt
     5881 aaatatttca ggatttggtt ttgatatttt caactcttca gatacaacca ttccatcaat
     5941 atattctttt atttttgaat tttcaagtct tttcttttga actgcagaaa ttccatttgt
     6001 tattataaca atagtatact tttttttaag atattgtaat atatcgattg cacctggaat
     6061 taaaaatgta cattcaccta aaaaatttaa gtacattttg ctaagagttt cagaatcaac
     6121 atccaaagat attttatttg caaaaagttc aaatctaagt aatttaagtt cattcaaagt
     6181 tataatattt ttttcaaggt cgagccaaag cttatcactt atatttctat atgactctat
     6241 ataattctca aaattaaatt ctaaatcaaa ctcagataga agttttttaa aagcatgtga
     6301 ttcacttttc ttaaaatcaa ataaagtatc atctgcatca aaaaatataa atttatatgt
     6361 cttcatggtt tttactcctt tacaagatga ctgcaaaaat tactttactt tcactatttg
     6421 agtcattttg ccatttatgt tttgttccta aaggaacttt tacactatct cctttggaca
     6481 aagtaaattc atcatcatcc ataaaaagtt taacttctcc ctccaaaaca tatgcaattt
     6541 catctccatt atgagtaatc ctatcaacac aagaagaagt gtttggagct aaatccataa
     6601 ttgcaaattc taaattacca ctagagtctg gaattaaaat ctcatatata acttctttgc
     6661 ttccaggtaa aataactttt tttctattat catgtcttac tatcaagttt tttttatcta
     6721 cctcagatac aaaaaatgta aataaaggaa cgtttagaga agaggctata gattttaatg
     6781 aatttacaga tggattagca agacctcgtt ctatttggct caataatgat ggtgtaacat
     6841 cagctagttt tgctaaatct cgaatactta agttttgttt ttttcgaact tcagctattt
     6901 tttcccctaa atttaaatca ttcatataaa tatcctctct ttttaattta aaaaatatta
     6961 acttaaaata atcaagtaaa atgattatgt agtatgaaat tattataaca tatagaatta
     7021 ggttttgaaa aaactatgtt caatataatt aaataaatta aaatataatt gacaaagtgg
     7081 atacagaata cttaaaatat atttaaataa aattaagcaa aagatagtta atttatgata
     7141 ggaggggata ttatgcaaat aacgactttt ggagctatat ttggtttatt aatagcaatt
     7201 attttaatta taaaaaaatt tcaagctgta tatagtttaa tgctaggagc atttattgga
     7261 ggattagttg gaggagcaaa tataacacaa actgtagatt ttatggcaaa tggagctatg
     7321 aatatatcac catcaattct tagagctttg gcatcaggtg tattagctgg aagtttaata
     7381 aaaacagggg cagtagataa aatatcagaa cagattgtaa aaatatttgg tgaaaagagg
     7441 gctttatttt cgattgccat ttcaactatg gtacttgctg gagtaggcgt aaatttggat
     7501 gtatctataa taactgtagc acctatagga ttatatatag gtagaaaatt aaattattct
     7561 aaattgtcaa tactattagc tatgttggga gggggtaaag caggtaatat aatatcacca
     7621 aatccaaata ctatagcagt agcagataat ttttctgtca atctctctag tgttatgatg
     7681 gcaaatataa ttccagcaat tattggagtt gttattacag ttattttagc aagtatatta
     7741 ataaataaag gaaataaagt acaatcatat gaaattttag agcaaagaga agatttacca
     7801 agtttattta aatcattatg tggtccaatt atagctatat ttctattgtt tttaggaaat
     7861 gtatctccta tagttataga cccaatgata gcccttccaa taggaggaat cgtaactcta
     7921 attgtcacag gaaacttgaa caattcaaga gaatatttag cttttggatt atctaagatg
     7981 caaggggtat gcatattatt acttggaaca gggactatcg caggaattat acagatgtct
     8041 gaattacaac agagtacaat aggtgcttta caatttttaa atatgccaca atttttattg
     8101 gcaccagttt cgggtatact tatgtcatta gcaacagcat catcaacagc tggtgctact
     8161 atagcatcat ctacttttca tgatgctata ataaatggtg ggctatcacc gatttcaggt
     8221 gcctcaatag taaatgctgg gtctagtgta ttcgagcaat taccacatgg ctcactattt
     8281 catactagtg caggtagtat aaacatggat ataggtgaaa gatttaagtt aattccatat
     8341 gaagcattga taggaatagt aatgactata atttcaacat ctattcaatt agttttataa
     8401 taaatataaa tatttaatga aaaaagtagg attttgttat taaatattga atttattata
     8461 gtaaaaaaga agattggagt tttaaagtga ataaaaaaaa gattgttatt atagggatta
     8521 tttattcatt tttagtagta ttttcactta caaatatgta tgtaaatatg gagtataatc
     8581 taaatgtatt tgaatatatt aagaagtcac ttccatttac agaagaagaa aaaaagtggt
     8641 tagaaaaaca caagaatttg atttacagct ctgaccaaag ttcacctcct ttgagatata
     8701 aaggtaagga agatggacag tataagggaa ttattgttga tttaataaat tctctgtcaa
     8761 ttcaaattgg tagagatttt tattttaaac caaataattg gtggaaagaa tctttcgtaa
     8821 attcaataga tgatagtata aagttttttg acttgattcc atcaaaagaa agggcaaata
     8881 aatttatatt tactgaccca atatacactt tgagtgcaaa tatattgaaa gataaaaagt
     8941 cccaagatat aaatagttac atggatttaa aggggaaaac agtagcaatt ccagaaggtg
     9001 attattctat aaatttttta aagcaaaaaa ttcaagatat aaacattttg ttgactccag
     9061 atataaagac tggagtcaac catttaatgt ctggaaaagt agacgcagtt gttggtgatg
     9121 aaccagtatt gcgatactat ataaataatt atggactttc aaataaatac agtgttttaa
     9181 gtaatcctat atatactaaa aaagcagttc ttgctgtacc taaacaatat gaagagctgg
     9241 ttagtatttt aaataaaggc atttttaaac ttcagaaaaa tggagtgtat aaagatttaa
     9301 agaaaaaatg gtattctacg tataatgaag ttgatgatat attgtatgag cgaggaattg
     9361 tgcctagtat ttatcttttt ataggtataa ttttaatatc aatttatgtt ttttatagct
     9421 atacatattt gttaaagata gaaatcaaaa ggaaaacaga acaggtaata gaaaataaaa
     9481 aaactttaga ggcaactttt aatagtatta cagatataat aatgcttgta gatgaaaata
     9541 acaatatagt agaatcgaac aaagtactat atgactttat gggtgaaatg agttataaga
     9601 tagcagattt gattagcatg ataaaaggtg ttattgaaaa taccttctct gaaaatacta
     9661 ataaaactag tgaaatagaa atacacaata aaattttaaa gataaacact tttcctgtag
     9721 agtataaaaa aaataatact gagtatatag tagttcttat taaagatata actaatgata
     9781 aaatagtaga ggcgaaatta cttagagaaa acaaaatgat atctatagga caattagctt
     9841 ctggggtagc acatgagata agaaatcctt tgggtataat aagaaataat tgctatctct
     9901 taaaagataa cgttacaatg gaagaagtaa atgattgtgt taaatcaata gaaagtaatg
     9961 tagatagggc aagtaatata ataaccaact tgttaaattt cgcaagaata tcagatgata
    10021 atttagaaca tataaatata agaaatttta ttgaaaatat agtgaaactt caatataaaa
    10081 tgttacagtt aaagaatgtt gaaataaaaa ttgactgtga acataattta gtatgctata
    10141 taaatggaga atcgttaaaa catgtattta taaatttaat ttctaattca atagatgcaa
    10201 tacatcaaga tggaaaaatt attatatact gttatgaaaa aaattattgt ttatttatag
    10261 attttaaaga taatggtgaa ggaataaaag aagatgccct aaaggacata tttaatccct
    10321 tctatacaac aaaaccaatt ggtgagggaa ctggtttagg tttatacatt acttataatg
    10381 agattaaaaa gaataatgga gatataagtg ttgaaagtaa attgggggtt ggaacttgtt
    10441 ttcatataaa aattccatta aataaagagg tgactatata atgaaaatac tattagttga
    10501 tgatgagcta gaatatggag tggtaatgaa aaaaattcta caaaagaagg gctatcttgt
    10561 agatatagca ctaagtggtg aagaagctat aaatataatt aaaaaagata aaaattatga
    10621 tttggttttg tctgatgtta tgatgaaaaa tatggatgga gtacagctat tagatagaat
    10681 taaatctatt aatagagata tagaggttat attagttaca ggatatggaa gtattgaaaa
    10741 tgcagttgat gctatgaaaa gaggagcttt atcttatttt ataaaaagta atcccattga
    10801 aaatttatta gaagaagttg aaaaggtaaa ggcaagtaaa atatctgttt ctgtacaaaa
    10861 aaataatctg gaatttactt tggaatctaa aaatagagat tttaataata tcataaaaat
    10921 agcaaaaaaa gctgcttgta aagatgttaa tatattaatc ttgggggaat ctggtgtagg
    10981 aaaagatata ttagctagat atatacatag cataagtcca agaaagaatg agatatttgt
    11041 acctgtaaat tgttgttctt tttcagaaaa tctattggag tctgagttgt ttggtcatga
    11101 aaaaggttct tttacaggag cagtagatag tagaaaaggt agatttgaac tttcgaataa
    11161 aggaactcta tttttggatg aaataggaga tatacctcta aatgttcagg taaaactttt
    11221 gaggacactt gaggacaaat ctatagagag gataggaagt aataaatcta ttaaagttga
    11281 ctttaggtta atttgtgcta tgaataaaga accaaaagtg gaaatatcaa atggaaatat
    11341 aagagaagat tttttttata gaataagtac aataacaata actataccac cgctaagaaa
    11401 gagaagagaa gacttaacta ctcttataga atttttctta aataagtacc aaattgaaca
    11461 tgataaaaag atacactcga ttgataagga agtaaaggat tttttattaa attacaatta
    11521 tccaggaaat ataagagaat taaaaaatat aataaataga cttgtagttt taagtgaaga
    11581 aggcaattta tcaaaagaca atttaaattt aatatcaaat aatgtataca tagatgataa
    11641 aataagtatt agacctttaa gagaaataag aaaagagttt gaatgtgagt atattgaaaa
    11701 agttttatct ttgtgtggaa ataatatttc aaatacagct aaaaaattgg agattagtag
    11761 aagacagtta accaataaaa tatcagagta taatattaag tgagaaaaaa acttctcatt
    11821 aagtgagaaa aaaatttctc aaactgtatt aaaagataaa cagaaaaaat ctgtttatct
    11881 ttttttatta taattttaaa aattaatatt tacaataatt attgctaaat tcaatattgg
    11941 tgtaaattaa aaatgaaaat ttctatgaca ttaatacata gaatatatat tttaaataat
    12001 tggcatagaa aatgctttat atattaataa acgtaataaa tacttttaat tgcgattaaa
    12061 tatattaagg gggattttca tatgaagcta gagctaggga atatatttat aaaaaatgtt
    12121 gaatttggag aaaagacaga agtaaaagat ggagtactat atattagtag cgaagaaata
    12181 gaaaagatag tattagaaga tgaaaggatt gtaagtgtaa atgttgaact tgcaagacct
    12241 ggcgaatcaa taagaatagc tccagttaaa gatgtaatag agcctagagt taaaattgga
    12301 gatgaaagca aaatatttcc tggaattata aataaagtga agactgtagg aagtggaaga
    12361 acccatgtac ttttaggagc ttgtgttgta acttgtggaa atatagttgg atttcaagaa
    12421 ggcgtaattg atatgagtgg tcctactgct aaatatacac ctttttcaaa aacaaataat
    12481 atatgtattg ttataaaagc aaaggatggt atagatactc atgattatga agaagcagct
    12541 agaattgcag gattaaaaat aggtgcatat gtaggtgagg caggaagaga agttgagcca
    12601 gatgaagtca ttgtatatga gacaaagcca ttattaaaac aagtaaaaga atatccagac
    12661 ctgccaacag tagcatatgt tcacatgtta caatcacaag gacttttaca tgacacttat
    12721 tactatgggg tggatgctaa acagatagtg cctacattta tgtatccaac tgaaataatg
    12781 gatggagcta taatatctgg aaactgtgta gcaccatgtg ataaggttac aacattccat
    12841 catttaaata atccagttat acatgactta tataaaagac atggaaaaga tttaaacttt
    12901 ataggagtta ttttgactaa tgagaacgta ttcttagtcg ataaagagag aagctctgat
    12961 atggtagcta aattaataga atttttagga gttgatggag ttctagtgac agaagaaggt
    13021 tatgggaatc cagatactga cctaatgatg aattgtagaa aatgtagtga agttggagca
    13081 aatgtagttt tgataacgga tgaatttcct ggaaaagatg gcaagagtca atctatagca
    13141 gacgctacta aggaagcaga tgcagttgtt tcttgtggtc aaggaaatct agtggttcat
    13201 ttcccagcaa tggaaaaaat tataggaact ttagattatg ttgaaatgat gataggtggg
    13261 tataaaggat gcttaaatga agacggaagc atggatgcag agctacaaat tataatagca
    13321 tcaactatag caaatggcta taatcatttg acagcaagat attattaaat aagtatttga
    13381 atataaagtt ctgttgatat aatcattggt ctaattgatg taacaactat aaagtgattt
    13441 ggaggattaa gagatgagta aaatcagagt ggttcattat ataaacaatt tctttgctgg
    13501 tataggtgga gaggaaaaag cagatattcc gccagaaaaa agggctggtg tagtaggacc
    13561 tggaatagca tttcagagtc aatttaatga tgatgcagag ataatctcaa ctgtaatttg
    13621 cggagatacg tattttggtg aaaatattga gagtgcaact caagaacttt taaaaatgat
    13681 aaaagaagaa agccctgatt tatttattgc aggcccagca tttaatgcag gtagatatgg
    13741 agtagcttgt gggactattt gtaaggcagt tgaagaagag ttaaatattc ctgtaattac
    13801 aggcatgtat aaagaaaatc caggtgtaga tatgtttaaa ttagatttgc atatagtgtc
    13861 tacaggaaat tcagcagcaa gtcttagaaa ggtagttcca ataatgacaa aactaggtct
    13921 taaattggtt agaggtgagg aaataggacc tcctgaagag gaaggatata taatgagagg
    13981 aataagaaaa aatttcttcc atgaacttag agggtctgaa agagcaattg atatgttggt
    14041 taaaaagatg aaaggggaaa gctttgaaac tgagtatcca atgcctgaat ttgatagagt
    14101 tacacctatg aaacctgtta aagatttatc taagataaaa cttgccctag taacttctgg
    14161 agggatagtt ccaattgata atccagacaa aattgaatct tcaagtgcta ctaaatatgg
    14221 aatttacgat ttaacagata tggattctat gtcaaataaa gaatttacaa ctatacatgg
    14281 ggggtatgac agagcatatg tccttgaaaa tccaaattta gttgtaccac tagatgtagt
    14341 tagagagctt gaaaaagaag gtgtaattgg agaattagta gattatttta taactactac
    14401 aggaacagga acgagtgttg gcaattctaa gagatttgga gaagagtttt ctaaaaaatt
    14461 gttagaagat gatgtagatg ctgtaatttt aacttctaca tgaggtactt gtactcgttg
    14521 tggagcaacg atggtaaaag agattgagag agctggtata gcagttgttc atatatgtac
    14581 agtagtacca atatcactta caataggagc taatagaatt gttccagcag tagggatacc
    14641 atatccactt ggaaatccta tgttaggaga agaggaaagt aaaaaaatta gaaagaatat
    14701 agttttaaaa gctttaaatg cactaacaga agatatagaa gaacaaacag tatttgaata
    14761 ataaaaatac aacacaacac tgaaataaaa aaagatatca aaaaataatt ttttaaaatt
    14821 attttacgat atcttttttt tattaggtaa attcgaaatt tgcatttttt aaaattaaat
    14881 ttataaaagt gataaattag tttattataa tattgataca caaattcaaa ttagatatac
    14941 tatgaaaagc gagattatta cattttggaa caaatattca acatattaga tcatattaat
    15001 tgaacagaaa aaattaactt tatataataa ttagaataat gataagaaag aaggtgtata
    15061 tattgatttc aattgccatt tgtgatgatg aatcctatat gctaaatcat ttaaaggaaa
    15121 atatagaatt atacatgaag cagaagaatt tattatataa tatagagctt tttaataaag
    15181 tagaagattt actatgcaat catgaaaagt ttaatattgt atttttagat atacagatgg
    15241 aagagattaa cggaatgcag gcagctagaa aattaaggtc atatggtaat gagtgcttta
    15301 taattttcgt tacagtttta aatgaatttg tatttgatgc ttttgaagta gatgctataa
    15361 attatctgat aaaacctcta tctaatgaga aactatataa aactttggat aaaatagtta
    15421 caaaacttga tgataatgaa agtaattata tcacaataca aaaaggttat tcatattgga
    15481 aattaaaact tgctgatatt ttatattgtg aagttataaa aagaaagatt tatgttcatt
    15541 taaagaaaga gactgtagat tattatgaga ctattgaaaa tttagagaga agtttaccaa
    15601 caaatttttt taggtgtcat cgtagttata taatcaattt acaatatgta tatggatatg
    15661 aaaatggtaa tgcagttatg gaaagtggag atagaatacc tgtttctaga ctacgtcaac
    15721 aaatattttc aaaagttatg cttgagttca tgaaaaatag gaggatataa gatgattaat
    15781 ttattttctt ccgatttatt tttaaagtac agttttttat tttcttttat tgtatataga
    15841 attttaatgg taatagtgca atactatttt ctaatcagtt ttacaaatgt taattcaaaa
    15901 ttttggtgtt ttattttata ttcgataatt tcaatttttt taatcattat aaatacatat
    15961 tttaatttat ataatttatt ttcttcacag attctatttt ttcttatgac ttttttattt
    16021 gtaaagtaca taataaaaca atctactgtt ttatctatag tatcaacttt gttagtatat
    16081 ttaattgaac aattagtata tggatttaca gctccattaa attacttgat atttactagt
    16141 gatataaata cagatattta taaatttgat ataaatatgg gactatcttc tttaattact
    16201 attataatag ctggatttat atattggtat agttctaaaa agtttaatat taaggtcatg
    16261 aactttgata aatatatagc aattttgatg attccattgt tgcttataat attatttatg
    16321 caatcatttg aatatagttc aaatataaat atagatacaa gtcttgggat tgtaaagctg
    16381 ctattaaata cttctataac tgaagaaatt caagcttttc ttttttctat aattggaact
    16441 atatgtgtat ttttttctct atttaccttt aagaaactaa ttcaagctct cgaagatgac
    16501 aaggagaggg caattatgaa tcaacagatt catgctcaaa aaaactatat tgaagaagcg
    16561 aaatcacgat tatcacaaac tatatccttt agacatgatt ttaataatca tttagctatt
    16621 gtcaatggat tgttgaaaaa agaccaaatt ttaaaagcac aagattattt aaataagctt
    16681 gaaaaagtaa caagtgacct atcattttct tgtaatacac agaatattgt tattgatgct
    16741 cttttcaaca ataaattaag tatagcaaaa caattaggca tagaggtaga ttgtgaagta
    16801 attatacccc aaagcactaa catgaacgat tttgacctat gtatagtgtt tgctaatgct
    16861 attgacaatg caattaaagc ttgtagagtt gtagataaac aaaataggta tttaaagctt
    16921 tccactaagt tagagggtgg attttttatg atagaaataa aaaatagcta taatccaata
    16981 aataattata caagtggctc aggtataggt cttttaaata taaaagaaat tgctaaaaaa
    17041 tatcaagggg ctataagtat agataagaca tcagattatt ttcaaataaa tgtattgctg
    17101 gttatttcat tacattgcgc tagtatttga taacaatttc attgaaaata gtatttgtaa
    17161 gctatattat gtacttgaat agagaaagtt tgatatatag aaatgaggag gttactaaaa
    17221 tgaaagttgg aaatataaat ggtcaagcac caattacaaa tggtttagat agttgtcaaa
    17281 gtgaggtaca aggcttagaa caaaagaaaa aatcattaca ggatgaaata gagaaagtaa
    17341 gaagtgataa aagtattgat ggtgaaacag ccaaattaaa aatagaagct ttaaaaaaag
    17401 aaatggaaga gattgaaaat aaaattcaag agttaaaagg aaataaagca aaaaaaacaa
    17461 ataaagaaga aaataatgtt tcagaagtaa ataataatct attagagaga aaaaaagaac
    17521 cttctaataa tgaaaatgta aaacaattat atgatgtttt tgaaagaagc aatgtagacg
    17581 aacaatggga taatacttat cgtgttctcc aagatgataa aaacttaaaa gtaaaattta
    17641 atagacctat atagtttatt tataaaaata gttaatattt taattatcac cactttttag
    17701 aagaatacac actttatttt aaagacccac atatttattt acagttagca catttatatg
    17761 tggttttata actattattt acaagtctat attgataact tttacatagt atataatgtt
    17821 taaatactta ttcaaattta tctatacata aacaaaaaaa gagattttaa aatctctttt
    17881 tagattgttg acttatggct ttttgattta ataaaatcaa gaagccgttt gaattttatc
    17941 tgttggctga tacccttctg atattgaaac accatttttg tttccaaaat cgtttaaaat
    18001 taagaactta ttatgaatga ctatttcatt atgaacaata agcagataac atgaatcttc
    18061 aatcaatgtt ttaacagtag cattaaatgc ttgcttatac agttctatcg tttgtttgaa
    18121 ctgtccatta aagtaaatat gagtcaataa cataactata tctacacaaa ttaatataaa
    18181 ttttttatac tgtacattat ctaactgttg attatctgta ttacaacatg attgaattta
    18241 aaaagccatc aacacataga atgttgatgg cctgaaaata gatttaaaat ctctttttta
    18301 ttatatatta attatttttt aaatttatat tttttgcatc agattttcta atagctaagt
    18361 caaaccctct aaatctaatc actatagggt cattaagagg agctatcttt ttcacttcaa
    18421 cttcagtgcc atctattagt cctaaggcta gaagtctctt cataagtttt tcatttccag
    18481 ctatattgtc tataattccc ttttgtccaa gttttaagtt gtaaacagtc attattaaca
    18541 cctcctaatg aaaatcatta tcaaacttta tatttataat atataacaaa aagagcaaat
    18601 tgtcaatata taacaaaaaa taaacatact aagttagtat gtttataaaa aatagtatac
    18661 atgggatact aatagcatct agcaaaaaac cacttactaa tggtacaact aaaaaggctt
    18721 ttggagaatc accatatttt tgtgtcaaag aactcatatt tgccagagcg ttcggagtag
    18781 ctcctattcc atgtccaatc aaaccactta ttatgatggc agaatcaaaa tcttttccaa
    18841 gtactctaaa gcaaataaat attgaaaata ggattataaa gattacttga aaagttacta
    18901 ttaagagaat aggaggtaat aatgtagata attcaaataa atctatattc ataagtgata
    18961 aagttaaaaa aattcccaat gaaagttctt ttaaaaaatc tataagttta aaatttaatt
    19021 ctagtatatt tatcttatca tttaaatttc taaaaataac agccgaaaac atacaagtta
    19081 caacagaggg taatagtata ttaaacgtta tatagaagca tctacttata atttctcctg
    19141 tatttataca aataaatatg agaagaacct gttccaaaaa tacagatggt gttattgttt
    19201 cggagaagtt attatttttt atcctattct tatttctaaa aaatttactt ccaaatctct
    19261 ttagatttct attatatcta ggaatcgaca agtctatatt tgatgatggt tttaatttat
    19321 atttatttat tagaaattta gctacaggac atcccaatat accacccata ataagtccta
    19381 ttgttgcagc agataatcca accccaactg ctccttctat accgagattt tctattgtaa
    19441 gtccaaatgc agcagaataa ccatgaccac cttccataga tacatttcca cacataagcc
    19501 ctaaaagagg ttcaagtttt ataatctttg atattgtaat agctaatata ttttgacaaa
    19561 atgccaatac tccacacaaa atccaatatc taaataatac actaccacct ttctttataa
    19621 gatttatgct tatttcaagt cctatagttg taaaaaagaa ggttatgaaa tttggcatta
    19681 aatttccact tatagatata tctgctatat taaaatattt aaaaaataaa tttagaaaac
    19741 aaaataatag acctcctatt actggtgcag gtatacagaa attatttaaa aagttaactt
    19801 tattcttcaa taaattacca attaaaaaga agaatataga tagtgtcaag gtttgcacta
    19861 tatcaaaact taaggtaatc aaaataagtc ctcctttgta attcaaagtt ttaattatat
    19921 aacttaaatt cttatgtatt gaaattttat tatcaaatgt atattaataa atgtatatta
    19981 aaaagaatca gtagatataa ttagatagtc ataaattaaa ttaaaatatt ttaatgagat
    20041 atgacttttt tagaattaaa aaccgtagta tattgatata atagaaataa gacttaaaaa
    20101 tctgttgata gtattattta taagtacagt aggaggataa aatgtttgaa aatttaccta
    20161 agatagattt acattgccac ttagatggaa gtgttagagt agaaaccatg cttgatatag
    20221 ctattaaaga gaaaatagat ttaccttcaa ataatatgga tgaaataaaa aaattagcaa
    20281 aggtttcttt taattgtact tcactagatg aatatttaga aaaatttgat ttacccttaa
    20341 aagtaatgca atctaaggaa aatttaaaaa gaattacttt tgaacttttg gaagatgcaa
    20401 gtagagaaaa tgtaaaatat attgaaatta gatttgcacc attacttcac acccaaaaag
    20461 gtatgagtgt taaaaatata attgagggta taattgaagg aattagagaa gctgaaagta
    20521 tttatgatat aaaaggcaat ttaatattag gttgtatgag aacaatgacc tcaaaagagg
    20581 cattattagt aattgaagaa gggaaatcat ttgtaaataa aggtgttgta gcagtagact
    20641 tgtgtggtcc agagaaagag ggattttgta aggaatataa agatgttttt aaattagcaa
    20701 gagaatatgg atataaagtt acaatacatg caggagaagc tgcaagtgga gaaaatgtat
    20761 tggatgctat aaatatttta aaggcggata ggattggtca tggggtaaaa attaaagacc
    20821 ataaaaaggc gtataattta gttaaagata aaaaaatatt gcttgaatta tgtccaacta
    20881 gtaatgtaca aactaagaca gtagattctt atgaagcaca tccattttat actttttata
    20941 aagataattt acatgtaagt ataaatactg ataatagaac tgtatcagat ataaatttaa
    21001 gttcagaact aaatgttata tttgatactt ttaaactagg attagaagac tataaaataa
    21061 tttatagaaa tgcagtagaa gctagttttg cagataaaga aactaaagag tatttgaata
    21121 gtttaattta atagataaaa atatttaaac tttaaattaa gctattaaat tgataaaaat
    21181 acattgtatt aggagaaaaa atgtgaaaga ttatgaagat gttgtttata ttaaactagt
    21241 caaaaaagaa cttgaagaat ggaagaaaaa tatattaaag aaaccttcta tatttgacaa
    21301 agcatcaaag ggtatacaga ataaatttaa tggagtattg ccagataaat atcatgaaat
    21361 aattacttct tctataaaag taatgacaaa aaccgtactg tttggatata aatatgctac
    21421 aaagccacca cttagaaata tgtcattaga agaaagagaa aaattagttt tagaaaaagc
    21481 taaaacttac aagactacag caatgattga aggggcagga acaggggcag gaggaatcct
    21541 cttaggttta tctgattttc ctttgctttt aggtattaaa gtgaaatttt tatatgatgt
    21601 agcttcaata tatggatatg atgttaaaga ttatagagaa aggatttata tattaaatat
    21661 attacagttg gctttttcta gtcaacagca tataaacaaa acttttaaat tgatgaataa
    21721 ctgggatgaa tatgtaaata gtctaccaga agacatcaat gattttgatt ggagaacatt
    21781 tcaacaagag tatagggatt atttagattt agctaagttt ttacaactaa tgcctggaat
    21841 aggagcattt gtaggatttt atgtgaatgg aaaattaatt gataaattat gtgaaactgc
    21901 tgtgtctgct tatagattga ggattcgaga gcttaagtta taagaaaaat tataacataa
    21961 aaaattagtt atacaatata tctatatgta tctaattttg cattgataaa aacaattatg
    22021 gataaaaggt aaagcatgat agaatctaat gtagaggttt gtattttaat ggaaaaattt
    22081 agtttttatt gcttaagata caaattgaat tacgaagaga ttgaattatg aagagaagta
    22141 attgggagga atattttcat gacaaatttg ccaaaacaat ttgatagctt caatgaagct
    22201 agacaaaaag gatttataaa tgcaaaggaa cttaaggaaa gtgggaaaaa gatggttgga
    22261 gttttctgta catttactcc agttgaaatt ccaatggcag ctggagcaac tgtagtaggt
    22321 gtatgcggcg ttagtgaaga gccaatacct gatgcagaaa gggtgcttcc aagaaatctt
    22381 tgtcctttaa ttaaatcaag ctatggacat gcaataacag atacctgtcc ttatttctat
    22441 ttttctgatt tgttgatagg agaaaccact tgtgatggta agaaaaaaat gtatgaagaa
    22501 cttgcaaaag ttaagccaac atatgtaatg catttgccaa atacttcaaa aggagaattt
    22561 gcctataaac tttggaaaga tgaaatgata agattaaaag aagaggttga gaaatcttta
    22621 ggtgtaacta taactgaaga agatataaga actgctataa aagataaaaa tgaagaaaga
    22681 gaacttttaa aagagtttta tgcacttggt aaattacaac catctgcact tacaggcctt
    22741 gagttacata atgttttata tcaagcaggt tttaaatttg accgtgcaga acttaaacat
    22801 tctttaagaa aagttataga tgatatgaaa gaaagatatg aaaaaggtga atgtcctgtt
    22861 caaaaagata agccaagaat attgataaca ggttctccta ttggtggaat aagcgaaaaa
    22921 atagttaaaa ctttagaaga tgcaggggca tcagtcgttg catatgaact ttgtggagct
    22981 attagatcaa acgatttatt ggttgatgaa gaaatagaag atgtatatga tgctttaaca
    23041 caaaaatata taaatatagg ttgttcttgt atgatgaata atgacaatcg tattgaatta
    23101 ttagatagaa taatagatga atataatgta gatgctgtaa tagatgtagt tttacaagca
    23161 tgtcatacat ttaatataga aagttataga ataagagaat ttgttacaaa agaaaaaaat
    23221 aagccattta tgtctcttga aactgattat tcaaaatcag atactgaaca attaagaact
    23281 agatttgaag cgtttgtaga gatgttgtag gaataaataa aagtaggagg aactatgttt
    23341 agtataggag ttgactcagg gtcagtggca acaaagggtg tgctatttga tggtgaaaaa
    23401 attattaaga aaataattat accaactgga tggagcccta aaagtacatc taaacaggtc
    23461 tatgagttgc taagtagtga aattgacaaa aaagatataa aaaaggtggt aggtacaggt
    23521 tatggaaggg gagtaatgga ttttgctgat aagaaagtaa cagaaataac ttgtcatact
    23581 agaggtattt actttttaaa caagaacata aggactattt tagatgtagg tggtcaagat
    23641 agtaaagtta taaatttaga tagagatgga aatgtattta actttataat gaatgataag
    23701 tgtgctgcag gaactggtcg atttttagag attacttcta accttttagg aagcgatatt
    23761 gaaagtatag atacattagc taaaggatat gaaccagtta atatatctag tatgtgtaca
    23821 gtttttgctg agtctgaaat tgtaagtctt ctagctcaaa acatttctac tggagaggta
    23881 gcagcaggga tacttaaatc tattgcaaat aaatccacct caatgttagc aagaggtgag
    23941 gtaatagatg aagttgcatt tactggaggg cttgcaaaaa gtaaagaact agtaaaaatg
    24001 atagaagaaa tactgggtaa aaaaattttt attgcagaag atactcaaat aataggagct
    24061 ttaggagctg ctgtaatagg atttagataa aaacatataa aaagaaaatg agaagctgaa
    24121 tttattataa ataaattcag ttttttattt tattttattt atttataaag gaaaactttg
    24181 gtataattga tttaaatgat tgtatatttg taaatacttg atatttagtc atatataaca
    24241 ttataatttt aaaaattagc tcaaaataag ggggagaaag cgtgaaaaaa tttacttcaa
    24301 aaaaagtaac aaggtttgtt gcgctgtttt taatatctat tttagtaatg tcaacaattc
    24361 ctgtatcagc tgacaatagc aatacattga atcagataaa aaaagcagaa tacagtgaga
    24421 cgtataaaca atatctaaat gatgctaaaa atggatgtac agaaaaatat aatgggatta
    24481 taccaaatcc atatcagttg gaaggtactc aaatccaaag taaaggaaga acagctccaa
    24541 catcttatga ccctagaaaa ttaggtctta tgacatcaat aaaaaatcaa gaggatttag
    24601 gaatctgttg ggattttgct gcaatggcaa ccttagaaag tttcttaaag ttaaataatt
    24661 atggagacta tgatttatca gaagaacact taagatggtg ggcttcagat ggtgaatatg
    24721 gatggtctgt aaatgatatg aatggtgctt taaattatga agctatggga tatttaacat
    24781 cttggtcagg tcctaaatta gaaaaagata tcccatacaa tggtagagta tctaaagcac
    24841 aaggagcaaa aaaaccaact aatatgaata cagcacctac tgtttttaat gtgacagatg
    24901 ctgtgtgtgt aagcaatgac ataaattcta caaaaaatgc tatattacag tatggagctg
    24961 taacatctgg ttattatgaa gatattaaat atcaaagtga tgaccaaaat tcatattatt
    25021 gtccaacaaa aagttttaat acaaatcatg ctatttcaat tgtaggttgg gatgataact
    25081 attctaaaga taattttaat gcaaatatta gaccatcaaa aaatggtgct tggttaataa
    25141 aaaatagctg gggagattat aattctgagg gtggatattt ctggatatct tatgaagaca
    25201 agacacttat gtctgatata gataattttt caatcaaagg tggtaaaaaa ccaaatgatg
    25261 atgagaagat gtatcaacat gactatgcaa gtattgtacc tttaatttca aaaaagataa
    25321 cagctgcaaa tgtatttgat ttcaatagag gcgatgaaac tctaaaatct gtaatgttct
    25381 taactgaaag tataggagct aagtatgaag tatattatgc tccagtagta aatggtatac
    25441 ctcaagaaaa caatatgaaa aaattaaaag aaggtactgc ccaatattca ggatacataa
    25501 cagttccaat tgattctttt gatataccag aaggaaaggg tgcaattgta gtcagtatag
    25561 aggggaaaaa tggagagtca actataggtt ctgagtcaaa tgtaccagga tatgatacat
    25621 ttaaagcaaa agctaattta ggtgaaagtt atatcataga taatactgga aaattctttg
    25681 atataaatag agatagtaac ttctatccgt gtaattttac tataaaagct gttacagaaa
    25741 agtcttctgg tgagagtatc ccaaatgagt ctttaattgg tagtgataga tatgaaactg
    25801 ctatcaaagt tagtcaaaat ggtttcaatt cttcagaaaa tgtagtttta gtaaatggca
    25861 gttcaatagt agatgcattg gcagcaactc cttttacatc tgctataaat tcaccaatat
    25921 tattgacaca aaaagaagct ttaaattcaa aaactaaagc tgagatacag agattaggtg
    25981 ctaagaaagt atacctaata ggtggagaaa attctataag taaagaaatt gaacaacaat
    26041 taaaaagctt aaatatatcg atagagagaa tatcaggaag tgatagatac aagacaagtt
    26101 tattattagc tcaaaagtta aatggtataa aaaatgtatc tcaaatagca gttgtaaatg
    26161 gagtgaaagg attagctgat gcaattagtg taggcgctgc agcagcagaa aataacatac
    26221 caatcatact tgcaaatgaa aagagcgaat tgcaaggagc tgatgaattt ctaaattcat
    26281 taaatataga gaaatcttat attattggag gaacagcatc cctatcaaac aatctagaaa
    26341 gtaagttaaa aaatccaact agattatctg gtagtagtag agacgaaact aattcaaaga
    26401 taatagataa tttttataaa aaagatactt taaaaaatgc atttgtagtt aaaaatggaa
    26461 tcaagaatca aaatgattta atagatggat tggcagttgg tcctttagga gcaaaaactg
    26521 ggtcaccagt aattttagtt ggtgataaat tagctgatag ccaaaaagaa gttcttaaaa
    26581 ataagacttt agaaaaagta actcaagttg gtggaggagc aaataaaaat gcatttaaag
    26641 agttagtaaa attaaaaagt gctaaataga gtacttaagt attaacatat attagtgtgt
    26701 attagtaact tatcttaata aaagctgaaa ataattactt caaattattg ataaataaga
    26761 taatcaatga ttgtaaagtt ttgttttcag ctttaaattt atgtagtata agtttaaaaa
    26821 cataaaaaag ggttacttta tatagaaata tagaaaatct tacattttat atataaataa
    26881 cccatattta attaactttt tatagtgttc taatagatat tattgaactt aatggtaaat
    26941 ataatgtgta agtttcattt aaagttggat tagattcatc tatatatctt gagcaaagtg
    27001 taattgataa gctatctgct tctataattt caccatatag aggacaactg ctaaagtaag
    27061 aatgtacttc aacatattta tttaagtttt cttgaacata atcgtaaaaa cggttttttg
    27121 tagtagtagc cataaaatca actcctttat tttttattaa agttgaaact tttaaaaaga
    27181 taaatatgat tacttctatt agaaactaag ttaaaaaata agcaaataga tatgaaaatt
    27241 agaataatat attatttata tcttaattat aacactagat aataaaaaat gctatataaa
    27301 attcagaatt ttcgaaagtt tttaagctta tttttaaata tactaataat actattgaca
    27361 ttagatagaa aaagtattat attgactata taaattattt tagtcaaact ggagggaaaa
    27421 gatgcctaaa tcatattctg ataaagaaag agagtatata ataaaaagac ttaaagaaga
    27481 agcaagattg tgtatggagc aatatggtat tagaaaaact actgttgatg agcttgtaaa
    27541 acgggtaaaa ataccaaaag gaacttttta tctatttttt caatcaaaag aattactctt
    27601 ttttgaggta ttaagagata tacatgactc tatacaaaaa gaaatcttat atgagataaa
    27661 tagagtagat gaaagtatta catgtgaaca attgacagat atatttatga aattctatag
    27721 gatggttgat agtacttcaa ttttaaatct catgataaat ggagaatttg agatattggt
    27781 gagaaagtta ccagattcta taattgaaga atactttaga catgatgact ttgaaattgg
    27841 agagattata tcttgcatac caaatgcaaa aaataaagac atagaaagct ttagtggagc
    27901 atttagagca gtttttctta ccatgctata taagcgcgag gttggaagta attgttttga
    27961 agatgcttta agattaatga taaacggatt agttatacaa cttatggaat agaatttaaa
    28021 ttttgtttgc taataacttt tattaaaaat tattaacaaa caaaaaaatt atattttatt
    28081 gaccatatag tcaaaatagt caaaaatttg aaagggtgat attgaatgat taaagttgat
    28141 gatttatcat ttagttatac agatagagat tttttacaaa atattaactt tgaagtagga
    28201 aaaggggaaa tactaggatt tttaggacca tcaggtgcag gaaaatctac attacaaaag
    28261 attctaattg gaatgataac taattatgga ggaagtgtca ttgtaaatgg agtagagagt
    28321 aaaagacact caaataaatt ttatgaaaat ataggagttg attttgaatt tcctagttta
    28381 tatgaaaagt tgactgcaat agaaaattta aaatattttg ggtctctata ttctaaaaaa
    28441 ctactatcta ttgatgagtt attaaaatca gtaggactag aaaatgaatc aaataaaagg
    28501 gtatctgagt attcaaaagg tatgaaatct cgattaaatt ttataaaagc tttattacat
    28561 aatccagata ttttattttt agatgaacca acaagtggtc ttgacccatc aaatagcaag
    28621 gttatgaaag atataatttt atcagaaaaa tcgaaaggta agactattat tttaacaact
    28681 cataacatgt tagatgcaac agagctttgt gacagagtag cgttcattgt aaatggtaaa
    28741 atatctgctt tagatacacc acataatctt attatgtcaa aaggagctat taaagttaga
    28801 tatacttact ttgataatgg agaaaaaact tctgaatgtt ttctgaacaa tactgctaat
    28861 gataaaaatt tgaatatgct tattgagaaa aataaacttt tatcaataca tagtagtgaa
    28921 ccaacattaa atgatatttt tattgagata acagggagga atttacaatg aggctaaaaa
    28981 atcttatttt aggagatata aagtttcaat ttaagtatgg tttttatttt ttatatcttt
    29041 ttttaagtat tatatatatt tgtattatca atgtatttcc aacttttatg agagaaaaaa
    29101 tagctataat tatgatttat tctgacccag cagcaatggg attgtttttt atgggagcta
    29161 ttgtacttct tgagaaaagt caaagggttt taaattcctt agctgtatct ccagtaaaag
    29221 tatctgagta tattttatca aaggtaattt cattaggagt aatatctagt attgtagcta
    29281 tgtttattgc tattacatta aatttagata atattataat atcaactata ggtacctttt
    29341 tttcttctat tatattttct ttgcttggat tgataattgc aagtaaagca tctagtttga
    29401 atcagtttat tgttttaagt attcctattg agattatatg ctttattcca ccaatactga
    29461 atgtacttct tgacacaaaa tcatatgcaa atttgtaccc ttttaatata tgtatttctc
    29521 ttattagtgg agataaaaat tttataatga ttaatatttt aattttaata tcaattataa
    29581 taataattta ttttataact tattatttta tttgtagcag ttggaaaaag gtaggtggag
    29641 taaaactatg ataaagatta taaatgcgtt taaacaagag tttgaacaaa ttaagagaga
    29701 tgctatgctt tttatagtat gtgtttctcc aatattatgt ggagtattta taaaatttgg
    29761 aataccatta atacagaata tatcacttaa caagttttat tatcaattaa atttagagcc
    29821 gtatttcttg atgtttgatt tacttttagc ttttattaca ccttttatgt tcttttttgc
    29881 ttctacaatg gtcatattgg gagaaattga tgacagcatt tcaagatatt taatagtaac
    29941 tccgcttggt aaaactggtt atcttatttc acgatttgga ataccaggta tcttagcatt
    30001 tattattact atgattctac ttatcttttt ttctctaact aaaatttctc tcttgttaaa
    30061 cttatcaatt tctttattag ttttattaca aggagttatt atatcaatat tagtgatttc
    30121 tttatcatca aataaactag aaggaatggt aattacgaaa ttctcaggtg tttttatgat
    30181 gggtatttta gcaccatttt ttattttaaa taaagcacaa tatattctgt tcttcttacc
    30241 aactttttgg atatcgaagg catttaagga agataattat gtctatatgt ttatttcaat
    30301 tgttatatca ttaatatgga ttttattatt atttaaaaag tttagtaaaa aaatagttaa
    30361 ataagaaaat ttaatatata aatgtaaggt tgacttgaca gtaatgttga aaaatgttac
    30421 atttaagatg taaagttaac cttacatgaa tggagcaaat atgaaaaata aaataaagat
    30481 attaagagaa aaattaggat tgacacaaga acaactaggg agattagttg gaacatctag
    30541 acaggctata aatgctatag aaactggtaa aaatgaacct tcaatatggt tggcatatga
    30601 tatttcaaga atttttaatg aaccaattga aagtgtattt ttatttgaag aaagtgaaag
    30661 aaaatcaaga gcacagataa gtaggggaga atattatggc tataagaaag ataagaacat
    30721 ttgatgatga aattttaaga aaaaagagta agtatgtaga aaacgtagat aataagataa
    30781 gagaaatatt aaatgacatg gcagagacca tgtacaatac tccaaatgga ggaggattag
    30841 ctgcatgcca agtaggagta ttaaagcgat tagttgttat agatttagga gaaggactta
    30901 ttaagcttgt taatcctgaa attattgaac aagaagggga acaaattgtt gttgaaggat
    30961 gtttaagttt tcctgaagta tggggtaaat taaaaagacc aaaaaaagtt acagtgcaag
    31021 ctctaaacga atacggtgag aaaatagaaa ttaaaggttc aggttttatg gcaaaatgtc
    31081 tttgtcatga gatagaccat ttaaatggta tagtttttac agataaaatt attgaacatg
    31141 taaaattgta agatagattg gttattgaat ttataaaata ttttatagta aggagttaaa
    31201 ttatgagatt atggcataag gatttaattg atgtattacc taaaaatcaa ttagtaagtc
    31261 aatggagaga gctacttgct ataaaaggtt ctatagataa aaaaggtact ccaaaccatc
    31321 tattagtgaa taaagtattg aattatagta tagatgaatt taaattttat acaaaaattg
    31381 tacatgatga aatgttaaaa agaaattata aacctaatga acttaaatat acaagtatat
    31441 taaaatggaa aaatagaaat tttgcaaatg atatatctaa tgaacatagt ttaaatttag
    31501 aaaatttata tgatgattgg cataataaaa tgtatttaaa gcaatgctta tataatttag
    31561 aagaaaaagc aacatgtgga ggaataccaa taaatgaatg gaatatatta ctttgtaaat
    31621 atagtaaaga ttatgaattg tggtctggaa atatcatgtt ttaattacta tagattaaca
    31681 ttatagtatt attgtatata aagaggtgat tatttgtata ataaaataaa atatattcca
    31741 ataaattgtg aaatagcttg taataaatta aaaaggagta tgccatataa atgggattta
    31801 aatatttatc gtggatgtga gcatggatgt aaatattgtt atgctattta ctctcataag
    31861 tacatcaact ccaataatta ttttgaagag atttatgtaa aaacaaatat agtagaaaaa
    31921 cttgagagac aacttaaaag cagtaaatgg aagaaagaag taatcaatat aggaggagtt
    31981 acagatagtt atcaaccaat agaagctgac tataaaatta tgccagaaat attaaacctg
    32041 ctaataaaat acaagacacc agctattatt tctacaaagt cagatttaat tttaagagat
    32101 tacgatttaa ttgataagct atctaggatt acatatatca atgtagcatc tacaattacc
    32161 acagtaaatg aagatacaca aaggcttatt gagccaaatg gtgtggattc aatgagacga
    32221 tttaaaatgt taaaagaatt tagaaaaact aacgcatcag ttggtctaca tattatgcca
    32281 attataccat atattacaga tgattttgat aatataaatt cgctatttag acatgcaaaa
    32341 gaatgtaatg tacattatgt tttacctggg actttatact taaggggtat aactagaggt
    32401 gttttttttg actttgttaa aaaagagttt cctgaattat ttgataaatt atcaatacta
    32461 tatagtgcag gttcacttaa tagggagtat aaaaatcaat tgtataaaat ggttaatgaa
    32521 cttagatata agtattctct atcaagcagt tactctaaaa taatgaagga aaagttaaaa
    32581 aactcaggag atgtacagat atcttttttt gattagtttt atataaaaaa atttttttta
//
LOCUS       DAMJVG010000044        31822 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.044, whole genome shotgun sequence.
ACCESSION   DAMJVG010000044 DAMJVG010000000
VERSION     DAMJVG010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 31822)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31822)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31822
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.044"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(<1..197)
                     /locus_tag="PC512_002185"
     CDS             complement(<1..197)
                     /locus_tag="PC512_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF2441925.1"
                     /translation="MNREKLVAFIRYLSLFILVVSYLKNVENTLYPVITMIILFLIII
                     NNQVRFFSLSNENKFILISYF"
     gene            381..725
                     /locus_tag="PC512_002186"
     CDS             381..725
                     /locus_tag="PC512_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YraN family protein"
                     /protein_id="HDF2441926.1"
                     /translation="MNNKEKGDFGEKVAVNYLLSKGAKILEKNYRLKIGEIDIIAKME
                     DEIIFVEVKSRSNIKFGYPCESVSFKKRKKIIGVANYYIIKNNLNNTPVRFDVIEVYL
                     LEKRINHIMNAF"
     gene            756..2357
                     /locus_tag="PC512_002187"
     CDS             756..2357
                     /locus_tag="PC512_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YifB family Mg chelatase-like AAA ATPase"
                     /protein_id="HDF2441927.1"
                     /translation="MLSIINSSNLVGIDSFLVKVEVDVSNGIPSFNIVGLPGKEIKEA
                     RERVKSAILNSGYKFPSTRIVVNLSPADIKKEGAFLDLSISIGLLRELIKKDENYIRE
                     SMFIGELSLDGKIRKVRGILPIIMGAKTQNIKRIFIPIENIKESLFVDEIDIIPIKSL
                     KECVDFLNEEIKVDKVRIMSFLDDKSRKENEELEKDNSYIDCKYTKINNEESKYDEDF
                     KDVKGNYFVKRSAEIAAAGNHNMFMIGPPGSGKTMIAKRVRTILPDISVEEMIEVSKV
                     YSILGMINETKGIIDKRPFRAPHHTTTKQSLIGGGMDARPGEIALAHRGILFLDEIAE
                     FDRKILETLRQPIEDGYVNISRVKYSAKYPCRVLLVAAMNPCPCGYYMSETECRCRSN
                     EIDRYINKISGPLLDRFDIFVEVNSIKYSDFNSLKQEESSQKIKRRVENARKIQINRF
                     KKDNIKNNSEIKAYNLFKYCKLEKEASKTAEMIFNKYNLSSRSYTKLLKMARTIADLE
                     ERDLINSQCIIEAFSFRKAYYSYFK"
     gene            2376..3476
                     /gene="dprA"
                     /locus_tag="PC512_002188"
     CDS             2376..3476
                     /gene="dprA"
                     /locus_tag="PC512_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HDF2441928.1"
                     /translation="MEKRDTYLWLKSIGGITTKTIEIIENEIVNIEDIFDFSEKEIYN
                     LKNISLNIRKNIVKYRGHAYLENIKELLYKKAIKYICKYDKEYPENLKNIYNAPKLLF
                     YKGDIGLVNNNFNIAIVGSRKPTAYGINCAKTISCQLSQYGVNIVSGLAIGIDAYSHI
                     GCMSGKSKTIAVLGSGVDNPLPKQNLHLSNKILENGGLLLSEYNINSTVAPYHFSNRN
                     RIISGLSDGVVVVEAAIKSGALITVDFALEHGKNVFAIPGNINSQMSRGCHKIIKEGA
                     KLIENIDDILNEYNIFNIIDKKINQKYDNISLNAKSKQIIEAIKREGNLHIDSICDYT
                     GIEIKYVNSIINELVLNELVVEMNNKTYSLNV"
     gene            3509..5596
                     /gene="topA"
                     /locus_tag="PC512_002189"
     CDS             3509..5596
                     /gene="topA"
                     /locus_tag="PC512_002189"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HDF2441929.1"
                     /translation="MAKTLVIVESPAKAKTIEKFLGKSHYTVKASVGHVRDLPKSKLG
                     VDIENNFEPQYINIRGKGDVIKELKKEAKKSKQVYLATDPDREGEAISWHLAHILNLD
                     ESEDCRIEFNEITKDAIKKAIKHPRNIDINLVDAQQARRVLDRLLGYQISPILWQKVR
                     KGLSAGRVQSVTTKLICDREKEIKAFIPKEYWTIDVEAKTVKDKDITLKFYGKNDEKI
                     ELENEEAVNEILKEMEGKDLKVEKIESKSRRKSAPKPFTTSMLQQEGANKLFFTTKKT
                     MMIAQELYEGIDIEGEGTVGLISYIRTDSKRISDEAKEKAKGYIVNNLGENYYKNTGD
                     KKEKKDTKKVQDAHEAIRPTSVDRTPESIKASLSKDQYKLYNLIWRRFVASQMEDSVF
                     DILNVECKIGDIVFKATGSKMKFDGYTKVYNFSEREDKILPSIEKGDILNIENILPDQ
                     HFTQPPARYTEASLVKTLEELGIGRPSTYAPTIATILNREYVEKQGTSLCPTELGIIV
                     TDILENNFHKFIDVDFTADMESKLDVIEEGNTDWKKIVSESYAPLKEAIEEALENIEK
                     VNMDEETDEICENCGSNMVIKYGRFGKFMACKNYPDCKTTRPIMNKIGVKCPKCEEGD
                     IILRKSKRGKAFYGCSNYPNCDFVAWNKPTGEFCEKCGSYMVEKVTKSETKTVCSNKE
                     CNKETKEHNDGKE"
     gene            5761..6546
                     /gene="codY"
                     /locus_tag="PC512_002190"
     CDS             5761..6546
                     /gene="codY"
                     /locus_tag="PC512_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HDF2441930.1"
                     /translation="MASEVLQKTRKINKTLQTSGGSSVSFDLLAGALGDVLSSNVYVV
                     SAKGKVLGLHLNDVQDSSVIEDEYTKQKKFSDEYTQNVLKIDETLENLNGEKILEIFP
                     EEHGRLQKYTTVVPILGSGQRLGTLVLSRYSNSFNDDDLVIAEYSATVVGLEILRAIG
                     EELEEEMRKKAVVQMAIGTLSYSELEAVEHIFAELDGKEGLLVASKIADRVGITRSVI
                     VNALRKFESAGVIESRSLGMKGTHIRILNDKLTDELKKLKNNQ"
     gene            6653..7918
                     /locus_tag="PC512_002191"
     CDS             6653..7918
                     /locus_tag="PC512_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HDF2441931.1"
                     /translation="MPLADKIRPKTMNDVIGQSHIIGNGKILSKILQSNFLPNMIFFG
                     PPGVGKTTVAEIIAERSNKSFYKINATNSSLEDIKKVISELGSINNVNGVLLYIDEIQ
                     SFNKKQQQSILEFMENGSITLIASTTENPYHYVYKALLSRSTVFEFKPLEKLDVEKGL
                     KRAVEVLNEDSYMDIECNNNAIEDIAILSDGDMRRALNILEVVVYSTKPNKDNITYID
                     SDVIRASTFNKIINYDKNGDSHYDILSAFQKSIRGSDPQASIHYLARLIKGGDLISIC
                     RRLLVIASEDIGLAYPNAIVIVKACVDSAMQLGFPEAKIPLAEATILLATSPKSNSAC
                     IAIMKAMDELDKEFVKDIPNSIKDSHYSGSKEIGRGCGYKYPHNFKNHYVKQQYLPDS
                     IKDSIYYIPQENKTEKNIKKYLEYLNSDF"
     gene            7949..8719
                     /locus_tag="PC512_002192"
     CDS             7949..8719
                     /locus_tag="PC512_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2441932.1"
                     /translation="MIIKLNSTYHSRVMKYLKKEPEYNLFIIGDIERYGYGNNFLNIW
                     ADVGEHGEIKAILLKYFEFMIFYSDGEYDVEGFYNLLRNTNYEEISGKICAVDALAKR
                     LGLNNLKVVDFCKLQTKKFLIDNNCNAKVKRIRLGNLKKTVKLYDLIDEFHSTTLENL
                     KNGLRTGRGYCIEINKQVVSMAKSTSENRTHAMIIGVGTHPKYRAKGLATKCLIKLCS
                     ELLRENKIPCLFYDNEEAGKIYKKLGFENIGKWGIYSK"
     gene            8828..9274
                     /locus_tag="PC512_002193"
     CDS             8828..9274
                     /locus_tag="PC512_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HDF2441933.1"
                     /translation="MKLSTKGRYGLKAMFELALNQDNGPVSLKFIAKKQKISDQYLEQ
                     IFSSLKKSGLVKSVRGAQGGYLLSKNAEDITVGDILVVLEGPVALSDCVLDEDVCENS
                     NMCVTKIVWEKMKKGIEDVIDSITLKDMINDYNKNKLENDITNIKK"
     gene            9292..10485
                     /gene="nifS"
                     /locus_tag="PC512_002194"
     CDS             9292..10485
                     /gene="nifS"
                     /locus_tag="PC512_002194"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase NifS"
                     /protein_id="HDF2441934.1"
                     /translation="MEKRRLYMDYSATTPIKKEVLDAMMPYLTDYFGNASSFHTFGRE
                     AKDALDKAREQVAALINAEPSEIYFTAGGSESDNWTLEGVAYANKNKGNHIITSKIEH
                     HAILHTCEYLAKHHGFEITYLDVDSEGKVDLKQLEDSIKDTTILISIMFANNEIGTIQ
                     PIKEISEIAKKHKILFHTDAVQATGNIPVDVKELGIDLMSMSSHKIYGPKGVGALYIR
                     KGVRLHNFVHGGAQEKSKRAGTENIPAIVGYGKAAELAKENMQNHVETLTRLRNKLID
                     GVLERIPYTRVNGSLDNRLPGNANFAFQFIEGEGILLLLDMLGIAGSSGSACTSGSLD
                     PSHVLLAIGLPHEIAHGSLRLTVGDFTTDDDIDYILENLPKVIERLRSMSPLYDDAKK
                     QGLVK"
     gene            10539..10979
                     /gene="nifU"
                     /locus_tag="PC512_002195"
     CDS             10539..10979
                     /gene="nifU"
                     /locus_tag="PC512_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly scaffold protein NifU"
                     /protein_id="HDF2441935.1"
                     /translation="MQYSDKVMEHFMNPRNMGEIDNASGVGEVGNPTCGDIMKIFLDI
                     DGDVIKDVKFKTFGCGSAIASSSMATEMIKGKTIKDALELTNKAVAEALDGLPPVKMH
                     CSVLAEQAVKAALIDYAQKNNIHIPELDGYVIDDAHDHDVEEEE"
     gene            11268..12347
                     /gene="mnmA"
                     /locus_tag="PC512_002196"
     CDS             11268..12347
                     /gene="mnmA"
                     /locus_tag="PC512_002196"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HDF2441936.1"
                     /translation="MNKKVMIGMSGGVDSSVAAYLLKQQGYDVIGVTMKLWQDDDVVE
                     IEGGCCSLSAVEDARRVANKIGIPFYVLNFREVFKEKVIDYFIDEYLEGKTPNPCIAC
                     NKHIKFDDFYKKARQIGCDYVATGHYAKIEKDESTGRYLLKKSVTDKKDQTYALYNLT
                     QEQLEHTLLPIGDYEKDRVREIAKEMGMAVHNKPDSQEICFVKDNDYANYVKKHSKKR
                     IEEGFFVDTKGNILGKHKGILYYTIGQRKGLGITFGKPMFVIDINPINNTIVLGDNED
                     LFKKELIAKDVNFISIDTLEEPLRVQAKIRYSAKPSPATIHRVGEDTIKIVFDEAQRA
                     ITKGQSVVMYDGDIVVGGGIIEKSL"
     misc_binding    12490..12728
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            12796..15435
                     /gene="alaS"
                     /locus_tag="PC512_002197"
     CDS             12796..15435
                     /gene="alaS"
                     /locus_tag="PC512_002197"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HDF2441937.1"
                     /translation="MEKMGLNEIRSKFLEFFESKGHYVANSYSLVPNNDKSLLLINSG
                     MAPLKNYFSGVEVPPSVRMCTSQKCIRTGDIENVGITARHATFFEMMGNFSFGDYFKR
                     ESIKWGWEFVTEWLNIPEDKIWVTVYEEDDDSYDIWAKEMNFPEERMVRLGKDDNFWE
                     IGTGPCGPCSEIYFDRGEEYGCDNPDCKPGCDCDRYLEFWNHVFTQFDRDEEGNYSLL
                     ENKNIDTGMGLERMGCIMQGVDTIFEVDTIKSILEAVEKLTGVKYGENPKNDISIRII
                     TDHIRAVTFLVSDGVLPSNEGRGYVLRRLLRRAARHGKLLGVKELFLQKLIDEVIKVN
                     DKAYPVLVEKESYIKKVVGIEEEKFNETIDQGTEILNSYIEVLKNEGKTVLSGQEAFK
                     LYDTYGFPIDLTKEILEEEHLSVDEEAFNEEMEKQKERARNARGNMDGESWKEDPLSK
                     LESTVDSTFNGYSEIYGEGTIEAIVKDDELVQSAEEGDKVSIVLDNTTFYPEGGGQVG
                     DCGLITNENLVLEVLNTKKGANNSIKHIGIIKSGRISNGDKVKTLVDRETRMSAARNH
                     SATHLLHKALREVLGEHVNQAGSLVTPERLRFDITHFEAISNEELKVIEEKVNNVILS
                     SLDIKCDIMNIKEAKEKGATALFGEKYGDEVRVVSMGDYSTELCGGTHLTNTSQVGMF
                     KILSEGGVAAGVRRIEAITGKAVYEYLKERDGIISEVCVNLKSKEDNLIQRISSLLEE
                     NKNLSKELHDMKAKMSLQSVDSIFDSKVEVNGVNLITNKFEGMDMDTLRETADNLRDK
                     LGSGVVVLANVVDDKVNFVVTATKDVLDKGIHSGNIVREVAKIAGGKGGGRPNMAQAG
                     ASDVSKVDQALSYASEVIKTQVK"
     gene            15460..15717
                     /locus_tag="PC512_002198"
     CDS             15460..15717
                     /locus_tag="PC512_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HDF2441938.1"
                     /translation="MEKDLDYTMKFEGIPEDRMSVGDTIDFVYKALVEKGYNPINQII
                     GYLLSGDSSYITSHKNARAIIKKFERDEILEEVITHYLNRK"
     gene            15727..17898
                     /locus_tag="PC512_002199"
     CDS             15727..17898
                     /locus_tag="PC512_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441939.1"
                     /translation="MRKKIMSLFAIVIMIFVSTASYGFAEEKGKVIFIDMNRTNLGSM
                     MNIPILKNEIEKRGYVALMNIRGDQGTDDRRSCASMGAGTRASVTTEDYINFQKVDQD
                     TAKAFEVATGQKAKEINDLGINRSINENLEYGEYGANLGSLGKTLSENGLKTSVIGNA
                     DIIENNQLVKNRNLCLVAMDQYGRIDSGNIDNINKKDSKMPFGISTDYDKLLDETKKS
                     YKNSDAIFVELGDTYRLDMYRLNLNDNTYDTMKKNIVKNINKYLEQVFSMVGENDTVY
                     IASAFPSDLDYKNKRRLSPIIKFSGEGKGLLESATTRKAGIVANLDVGVDILGTFGLE
                     NKEMVGRSYTLVNKEDNISYLKSLYERIVSISSIRSTIINGFVGVISASWVIAMFAIF
                     FRNYMPHKERVFKVLKEFIKLGIIMPLSFMLAPLMNFKTPISISLGIFATTLILYLLG
                     RKLFKDNDIKHMGFFATLTILVIVIDSVFGTYLMQNNIMSYDAVIGARYYGVGNEYEG
                     VTIASAVFGLAVLLHYKKVSKLLVVIFSLIILITSAYPSMGANVGGAISECVAYLLFI
                     MLIYDIKIDFKKAVLLAVSAVVVVFAFAALDILSGSESHLGMFVQRIFLNGPGEILQT
                     FGRKIQMNMQLAQTSVWVNILLVGIGVIAVLIFKPSRHFRKIMNNFPILFKGFIASMV
                     GCIITLLVNDSGIVAASTASIYILIPLIIISINMIIFEKNN"
     gene            18104..18529
                     /gene="ruvX"
                     /locus_tag="PC512_002200"
     CDS             18104..18529
                     /gene="ruvX"
                     /locus_tag="PC512_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HDF2441940.1"
                     /translation="MLDGRIMGLDVGDKTIGVAVSDLMGLTAQGVKTIKRVGKKKDIE
                     ELKAIIKEKQVNKIVSGLPKNMNGTLGPQGEKVIKFCELVKAETGIDVEFWDERLSTV
                     AAERSLLEADVSRQKRKKVIDMLAAVIILQGYLDFKINS"
     gene            18607..18894
                     /locus_tag="PC512_002201"
     CDS             18607..18894
                     /locus_tag="PC512_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HDF2441941.1"
                     /translation="MEENIINLIDENGVESQFEIILTLEAEGKEYAILMPLDDEEAEE
                     ALIFRIDEDEEGEILIPLESDEEYETVVAVYTAIMEEEGLNYDEDESNGLN"
     gene            19176..19634
                     /locus_tag="PC512_002202"
     CDS             19176..19634
                     /locus_tag="PC512_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HDF2441942.1"
                     /translation="MANTMDLLKDKLKETGFKITPQRRAIVEILLKHDHSHLSSEEIY
                     DLVRVDCPEIGLATVYRTMQLLDEIGLISKLNLDDGCIRYEISLHKEDCHNHHHLICK
                     NCGKIMEAKEDLLDNIEKEIQSLYKFKILDHDVKFYGLCDECNGVSDSEE"
     gene            complement(19751..20488)
                     /locus_tag="PC512_002203"
     CDS             complement(19751..20488)
                     /locus_tag="PC512_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HDF2441943.1"
                     /translation="MRGKTHCAIGILTAIQTSLIFKIPISLVDILVSATFAVLPDLDK
                     SNSMVSNFILKNNVSKYIYRIFIYAVNIIIFFISININDNFYLSAIITFVAIIIIEAK
                     LTHTFLRKVFLSLIFILLAICLYIIEVEIYFTIFCLMLSIFPWLKHRSFSHSIFATII
                     VYFLLKQIELITNINNLSFYGTIGYASHMFLGDLFTKQGIPIFYPLSEKKISLGFLTV
                     GGPFSNFIEKSFIFVLIGLIIFSILKL"
     gene            20705..22381
                     /locus_tag="PC512_002204"
     CDS             20705..22381
                     /locus_tag="PC512_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HDF2441944.1"
                     /translation="MQLFKKNTNKIKVMALGGLNEVGKNMTVVEYKDEIIVIDAGLSF
                     PEDEMLGVDIVIPDITYLVKNRDKIKGIFITHGHEDHIGALPYILKKINVPVYGARLS
                     IGLIQVKLKEHKMNNVKLNVIGPRQVIKLDNMEVEFLKNNHSIPDAYSIAIHTDQGII
                     YHTGDFKIDLTPIDGDVMDMHRICELSKKGVLLMLADSTNAEKPGFTMSEKTVGVGLD
                     ELFAKGNGRRIIVATFASNIHRLQQIINTAEKFNRKVAISGRSMVNVVGVAKELGYLD
                     ISDDMLIDLNDICKYEDSELVIITTGSQGEPMSALARMAFSEHKKVEIKSGDLVIISA
                     HPIPGNEKLISRVINFLFEKGAEVVYSDIADIHVSGHACQEELKLIHALVRPKFFMPA
                     HGEYRMLKRHAEIAEQLGMDKENIFVMQTGDVLELDKNSAKVANRIQTGNILVDGLGV
                     GDVGNIVLRDRKHLSEDGLMIVVVTISKDEGKVLAGPDIISRGFVYVRESEDLMDGAK
                     DIIKNVLNECEEKNIKEWAYLKNNIKENLKEYLYQKTKRNPMILPIIMEV"
     gene            22589..22789
                     /locus_tag="PC512_002205"
     CDS             22589..22789
                     /locus_tag="PC512_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore protein"
                     /protein_id="HDF2441945.1"
                     /translation="MDDVSRQNAIKALKQTKMEIAGEYGMNYEDAFEIIENASNKGVL
                     EGYFKKLEKKKNLGQGISRHLE"
     gene            22843..24006
                     /locus_tag="PC512_002206"
     CDS             22843..24006
                     /locus_tag="PC512_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HDF2441946.1"
                     /translation="MKKLASTALAILIALTPLSFSFANNKENADANQLNISSKSAILM
                     DVGSGQILYEKDAHKKLPPASVTKVMTMLLIVEALDSGKIKLDDEVQVSETASSMGGS
                     QIFLEPGETQKVDTLLKGIAVASANDACVAMAEHLAGSVEGFVDRMNAKAKELNMNDT
                     HFANTNGLPVANHYTSAHDIALMSRELLKHEMISKYLTTWMDKVVVGKKQVTVGLANT
                     NKLIKHYQGATGVKTGFTQEAKYCLSASAKRGNTHLVAATLGAETSPERFNDASSLLT
                     YGFANYESVKLCSKGDNIATLTLDKADENKVKLVAKEDLNALIKKGSSKEFEKKIEIV
                     KNPKMPIKKGTVLGKIKICKDKKVIGEVELINTKDINKASYLQMLQRIIDNMI"
     gene            complement(24217..24639)
                     /locus_tag="PC512_002207"
     CDS             complement(24217..24639)
                     /locus_tag="PC512_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2000 domain-containing protein"
                     /protein_id="HDF2441947.1"
                     /translation="MENKNSKCVMVIDENLPMGIISNTAAIMGITLGKHAPETVGPDV
                     IDKTGNSHLGIIDIPVPILKGNKEIIKDLRKKLYTLEFNDLTVVDFSDVAQSCNLYEE
                     FTQKIASVPEDELQYFGIAIYGNKKKVNKLTGSMPLLR"
     gene            complement(24660..25496)
                     /locus_tag="PC512_002208"
     CDS             complement(24660..25496)
                     /locus_tag="PC512_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF2441948.1"
                     /translation="MRQEERTVCFDRELKIEAYRFKGIMQKFPNHFHEHYVIGFIEKG
                     QRYLSCKNKEYTTSTGDLLLFNPFDSHTCEQIDDKVLDYRCINIKPEIMKKTVFEITG
                     KNYLPKFNQPVIFRSELVPLLQELHYIIMEEELDFKKEELFFFLIEQLIEEHTEPNLQ
                     SNLENTNIEIQAVCDYLENNYAEHIILDELSTIAGMNKYSLLRNFTKLKGITPYRYLE
                     NIRVNKAKKLLEKGVEPIDAAIQTGFVDQSHFTNFFKNFIGLTPKQYQNIFINDDSNN
                     FK"
     gene            25794..26390
                     /locus_tag="PC512_002209"
     CDS             25794..26390
                     /locus_tag="PC512_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HDF2441949.1"
                     /translation="MLSMNIGEIVASLVGIAMAISIHEFGHAYSAHLLGDDTAKAYGR
                     MTLNPVRHVDPIGLLAMFILKIGWAKPVPVNPNNFKNYKIGNLIVSLAGVFCNVLTAI
                     LCVIINKYVHMYAINTIAEYVFLYSIGFAAFNLLPIPPLDGWGVISTFVPYKWNEYLY
                     KFESMSYIILLIALFTGMYRIILTPIYAVLLKIVYLFV"
     gene            26420..27139
                     /locus_tag="PC512_002210"
     CDS             26420..27139
                     /locus_tag="PC512_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HDF2441950.1"
                     /translation="MKYNIQLQVYEGPLDLLYDLITKHKIDIKDISIIDITKQYLNYL
                     KMLDKMDLEITSEFITMASKLLEIKSKYLLYKQKDEEEDPRIELMEKLEEYRKFKVAS
                     QDIKENITYVNERFYRNKEEIIIDDNVDLEDISIEAIKNILPYIFKVKTSQIENANDE
                     KLDKIVRKKIISVEEKILYIRDIIKEKIEVTFTNIIKSYENDEIIATFLSILELIKEK
                     EIVVVQDIFFDDILIRKSSEC"
     gene            27141..27680
                     /gene="scpB"
                     /locus_tag="PC512_002211"
     CDS             27141..27680
                     /gene="scpB"
                     /locus_tag="PC512_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HDF2441951.1"
                     /translation="MKREDIKYIIESVMFAYGEPISIKELNYIINKELSSKEIEIMLN
                     LLIEEYREQNRGIQIIKLENKYQMCTNKDYAEYIKKIIEPKKKKSLSQATLETLTIIA
                     YKQPITKVEIEDIRGVKCDKVLQTLFENELIREAGRLNKIGKPIIYKTTDEFLKLLNI
                     ESLEELPPIENYQEVATNE"
     gene            27842..28471
                     /locus_tag="PC512_002212"
     CDS             27842..28471
                     /locus_tag="PC512_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2953 domain-containing protein"
                     /protein_id="HDF2441952.1"
                     /translation="MELNELFNFKYLIIAVIFIISVTMLILISHINILIIADIKNKDI
                     CLKLNIKYMFNLININRQLYPAENSKNNDKKEGMKNNIDSSILLADDLLSIYRLLKKI
                     KIHELYSNINFGTGNIGLTSSVYVLINTLYGNLFNMIDAEKMYLNVNPDFTKDYVLGN
                     IRIHIRPRIKALFNIIIMINKIMNKNKGNKEGDSNESNRFDTESYGNNS"
     gene            28425..28853
                     /gene="ytfJ"
                     /locus_tag="PC512_002213"
     CDS             28425..28853
                     /gene="ytfJ"
                     /locus_tag="PC512_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GerW family sporulation protein"
                     /protein_id="HDF2441953.1"
                     /translation="MRATGSIQSLMETTLETIKGSIDANTIIGDPIKTDTTVVVPISK
                     VTIGFGIGGGEYSKGYDDKDREIELKNEKSDTNFAGGSAGAISVQPVAFVVVESGETR
                     IMSLDSNINLVDNILSITPRVLEKIQNISQSNKNQDKNNM"
     gene            29101..29541
                     /locus_tag="PC512_002214"
     CDS             29101..29541
                     /locus_tag="PC512_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2441954.1"
                     /translation="MSDKELSILLLESMNNFHNLIKIINNERYKKDKVLTERQFFALV
                     KIRKHDKIELKNLSRDLHVSTSSLCILLNKLVEQEYVYREEDSRDRRNTFYGITKNGE
                     KILDNEILKFVSIISDKMDCLDIDNKDKLFTSLEESKNIIEQLF"
     gene            29557..31008
                     /locus_tag="PC512_002215"
     CDS             29557..31008
                     /locus_tag="PC512_002215"
                     /EC_number="3.4.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl aminopeptidase"
                     /protein_id="HDF2441955.1"
                     /translation="MNIKYSKEILKSLENAITVVALFEGEDVSTTFDKINMISRNFNS
                     KENSIDTVTLIENNNLVNVCLVGFGKRELLNREKIRIIGGNLCKKLKNILKNEAYKSS
                     DVNVLNLNLNSDEIGSFVEGILLGNYKFDKYKTKIKDFERKEVDTITIFTEKEVECQI
                     EKAKILANSTIIARNLVNEPSNVIYPKTLAVETVKLGAEFGFNVDVYEEEKIKALGMD
                     AFFAVSRGSINKPRFIVMRYFGDKESTDILGLVGKGLTYDTGGYSLKSNASMLDMKTD
                     MAGAASVIGAMCAISQSKLKKNVIAVVAACENALSGGSYKPGDIISSMAKKTIEVLNT
                     DAEGRLTLADAIYYIINNEKVTKVVDVATLTGAALTLLGNVATPIVTNNDDFYCELEK
                     AATLSGERVWKMPIYDEFKDMIKGEEADLKNTGGKNAGCITAGAFIGEFVGNTPWIHM
                     DIAGTSTSSKSIGYKAKGATGEPVRTLYYLAEI"
     gene            complement(31099..31767)
                     /locus_tag="PC512_002216"
     CDS             complement(31099..31767)
                     /locus_tag="PC512_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YwaF family protein"
                     /protein_id="HDF2441956.1"
                     /translation="MFKIFLFSSEQFVSLFIFGLFLYYCPKLTKNILPYSYTVEKIIC
                     TLLVIIMALEQLLLISSGNYSTLNSLPIGINYICIYLCIAILIFKQYHLFNIFFSWSL
                     VCSVGELIFSKNLGYEFPSLIYFIFIFSKCLIIYADIYMVDVRKFRVNRYALRDNLAI
                     CFIYFSFIFLLNTFTNSRYYYGFLSHSTTAIFTFIFVTSIMYIPALLFNRDTFILEKK
                     KKSK"
BASE COUNT        12949 a         3269 c         5683 g         9921 t
ORIGIN      
        1 aaaaagtaag aaataagtat aaatttattc tcatttgata aagaaaaaaa tctaacttga
       61 ttatttatta taattagaaa taatattatc atagttatga ccggatacaa tgtattttca
      121 acatttttca aatagcttac aactaatata aataaagata aatatcgtat aaaagcaact
      181 aatttttctc tgttcattaa aggcactcct ccaaaaaaat aaacttttac tatgaaaact
      241 agaataatat cataaaagaa taaagtcaat aaaagtattt attaatattg atggaaataa
      301 aatcaatcca aaaacttgaa tagtaaaatt gtatactgac aataatttaa aagtgaaaat
      361 ttaatgtatt ggagtgaata atgaataata aagaaaaagg tgattttgga gaaaaagtag
      421 cagttaatta tttgctatca aaaggagcaa agatactaga aaaaaattac agattaaaga
      481 taggggaaat agatataata gcaaaaatgg aagatgaaat tatatttgtg gaggtgaaat
      541 caaggtctaa cataaagttt ggctaccctt gtgaatctgt aagcttcaaa aaaagaaaaa
      601 agataattgg agttgcaaat tattatatta taaaaaataa cttaaataac actcccgtaa
      661 gatttgatgt tatagaggta tatttattag aaaaaagaat aaatcacata atgaatgctt
      721 tttaaaaaag ataatgtttt tggaaaggat taaatatgtt aagtattatt aattcaagca
      781 acttagtagg aatcgacagc tttttagtta aggttgaagt agatgtaagc aatggaatac
      841 ctagttttaa tattgttggt cttccaggca aagaaattaa agaagcaaga gaaagagtaa
      901 agtcagcaat tcttaatagt ggatataaat ttccaagcac gagaatagtt gtaaatttat
      961 caccagcaga tataaaaaaa gaaggagctt ttttagattt atctataagt ataggccttt
     1021 taagagagtt aataaaaaaa gatgaaaatt acataagaga aagtatgttt ataggagaat
     1081 tatcattaga tgggaaaata agaaaagtaa gaggtatatt gcccataatt atgggtgcaa
     1141 aaactcagaa cataaaacgt atttttatac caattgagaa cataaaagaa agtctatttg
     1201 tagatgaaat tgatataatt cctattaaaa gtttaaaaga atgtgtcgat tttttaaacg
     1261 aagagataaa agtcgataaa gtaaggataa tgtctttttt ggatgataag tcaagaaaag
     1321 agaacgaaga attagaaaaa gataatagtt atatagattg caaatatact aagattaata
     1381 atgaagaaag taaatatgat gaagacttta aagatgtaaa aggaaattat tttgtaaaga
     1441 ggagtgcaga aattgctgct gctggaaatc ataatatgtt tatgattgga cctccaggct
     1501 caggaaaaac tatgattgca aaaagagtaa ggacaatttt accagatata agtgtagaag
     1561 aaatgataga agtaagtaag gtctatagta tattgggtat gataaatgaa actaaaggaa
     1621 taattgataa aagacctttt agagcacctc atcatacaac tacaaagcaa tctttaattg
     1681 gaggaggaat ggatgcaaga cctggagaaa ttgctttagc acatagaggt atcttatttt
     1741 tagatgagat agccgaattt gatagaaaaa tacttgagac tttaagacaa cctatagaag
     1801 atggatatgt aaatatatcc agagtaaagt acagtgcaaa atatccttgt agagtactgt
     1861 tagttgcagc tatgaatcca tgtccatgtg gttattatat gtcagagaca gagtgtagat
     1921 gtagaagtaa cgaaattgat agatacataa ataaaatatc aggtccattg ttagataggt
     1981 ttgatatttt tgtagaagtt aattctataa aatattcaga ttttaattct ttaaaacaag
     2041 aagaaagctc tcaaaaaata aagagaagag tagaaaatgc tagaaaaata cagataaata
     2101 gatttaagaa ggataatata aaaaataata gtgaaattaa agcttacaat ttatttaaat
     2161 attgtaaact ggaaaaagaa gcttcaaaaa cggctgagat gatatttaat aaatacaacc
     2221 taagcagtag aagttataca aaacttttaa aaatggcaag aacaatagca gatttagaag
     2281 aaagagactt gataaattca cagtgtatta tagaagcttt ttcatttaga aaggcttatt
     2341 atagttattt taaatagttt tttgaggtgg attttatgga aaaaagagat acttatttat
     2401 ggttaaaatc aattggtgga ataacaacaa aaacaattga aataatagaa aatgaaatag
     2461 taaatattga agatatattt gatttttctg aaaaagaaat atataattta aaaaatataa
     2521 gcttgaatat tagaaaaaat atagtaaaat atagaggtca cgcttattta gaaaatataa
     2581 aagaactact ttacaaaaaa gcgattaaat atatttgtaa atatgataaa gaatatcctg
     2641 aaaatttaaa gaatatatac aacgctccaa agttattatt ctacaaaggt gacataggct
     2701 tagttaataa taattttaat atagctatag taggttcaag aaaacctaca gcctatggaa
     2761 ttaattgtgc aaaaacaata agttgtcaac tatcccaata tggagttaat atagtaagtg
     2821 gattagctat aggaatagat gcatactcgc acataggttg tatgagtgga aaatctaaaa
     2881 ctatagcagt acttggttca ggagtagaca atcctcttcc aaaacaaaat ttacatttat
     2941 caaataaaat attagaaaat gggggattat tattatcaga gtataatatt aactcgacag
     3001 tagccccgta ccatttttct aatagaaata gaattatcag tggtttaagt gatggagtag
     3061 ttgttgtaga agcagcaata aaaagtggtg cactaatcac agtggatttt gctcttgaac
     3121 atggaaaaaa tgtttttgca atacctggta atataaattc tcaaatgagt agaggttgtc
     3181 ataaaattat aaaagaaggt gcaaaattaa ttgaaaatat agatgatatt ttaaatgaat
     3241 ataacatatt taatattatt gataaaaaaa taaatcaaaa atatgataat ataagtctaa
     3301 atgccaagtc taagcaaata attgaagcta taaaaagaga aggaaacttg catatagata
     3361 gtatttgtga ttatactggt atagaaataa agtatgtaaa ttcaataatc aatgaattag
     3421 tactaaatga gttagtagta gaaatgaata ataaaacgta cagtttaaat gtataaatta
     3481 agattaggta gtgggggtgt atggttttat ggccaaaaca ttagtcatcg tagaatcgcc
     3541 tgcaaaagct aaaactatag aaaaattttt agggaaaagt cattacacag ttaaagcatc
     3601 agttggtcat gtcagagatt tacctaaaag taaattaggt gtagatatag aaaataattt
     3661 tgaacctcaa tatataaata taagaggaaa aggcgatgta ataaaagaat taaaaaaaga
     3721 agctaaaaaa tctaaacaag tatatctagc aactgaccct gatagagaag gtgaagctat
     3781 atcatggcat ttagctcata tactaaattt agatgaatct gaggattgta gaatagagtt
     3841 taatgagata actaaggatg caattaaaaa agcaattaaa catcctagaa atattgatat
     3901 aaatttggtt gatgcacaac aggcaagaag agtgctagac agacttttag gttatcaaat
     3961 aagtcctata ttatggcaaa aggttagaaa aggtcttagt gcaggtagag tgcaatctgt
     4021 tacaacaaag ttaatttgtg acagagaaaa agaaataaag gcatttattc caaaagaata
     4081 ctggacaata gatgttgagg ctaagacagt aaaagacaaa gatataactt tgaaatttta
     4141 tggtaaaaat gatgaaaaga ttgaattaga aaatgaagaa gctgtaaatg aaatactaaa
     4201 agaaatggaa ggtaaagatt taaaggttga gaagatagaa tctaaatcaa gacgtaaatc
     4261 agctccaaaa ccatttacaa caagtatgct tcaacaagaa ggagcaaata agttattttt
     4321 tactactaaa aaaacaatga tgatagcaca agaattatat gaaggtatcg acatagaagg
     4381 tgaaggtact gttggtctta tatcatatat aagaactgac tctaaaagaa tatctgatga
     4441 agcaaaagaa aaagctaagg gctatatcgt aaacaattta ggagaaaact actataaaaa
     4501 cactggtgat aaaaaagaaa aaaaggatac taaaaaggtt caagatgccc atgaggcaat
     4561 aagaccaacc tcagttgata gaactcctga gagtataaaa gcctcattga gcaaagacca
     4621 gtacaagtta tacaatttaa tttggagaag atttgtagct agtcaaatgg aagattcagt
     4681 gtttgatata ctaaatgtag aatgtaaaat aggcgatatt gtatttaagg caactggttc
     4741 aaaaatgaaa tttgatggtt ataccaaggt atataatttt tcagaaagag aagacaaaat
     4801 tttaccaagt atagaaaaag gagatatatt aaatatagaa aatatattgc cagaccaaca
     4861 ttttacacaa ccaccagcaa gatatacaga agctagttta gtaaaaacac tagaagaact
     4921 aggtataggt agaccaagta cgtatgctcc aacaatagct actatactga atagagagta
     4981 tgttgaaaag caaggaacaa gtctatgtcc aacagaactt ggaataatag ttactgatat
     5041 tttggaaaat aatttccata aatttataga tgtagatttt actgctgata tggaaagtaa
     5101 acttgatgtt atagaagaag gcaatacaga ttggaaaaag attgtatcag aatcatatgc
     5161 accacttaaa gaggctattg aagaagctct tgaaaatata gaaaaagtaa atatggatga
     5221 agaaactgat gagatttgcg agaactgtgg gtctaatatg gttatcaaat atggtagatt
     5281 tggaaagttt atggcttgta aaaactatcc cgattgtaaa acaactagac caattatgaa
     5341 taaaattggt gttaaatgtc caaaatgtga agaaggagat attatactta gaaaatctaa
     5401 aagaggtaaa gctttttatg ggtgttctaa ttatccaaac tgtgactttg tagcttggaa
     5461 taagccaaca ggagagtttt gtgagaagtg tggttcatat atggttgaaa aagtgactaa
     5521 atctgaaaca aaaacagtgt gttctaataa agaatgtaat aaagagacaa aagagcataa
     5581 tgacggaaaa gagtgaaaat tgaaaaaaat cacataattc tcttgaaaaa ggttccaatc
     5641 tatgataatc tttcaagtgt aaacaactaa tagaaaaata aattttcatt aaatgtgaaa
     5701 ataatattag aaaatataaa aggttattaa aaggcctaaa tttcatgagg agatgattaa
     5761 atggcaagtg aagtgttaca aaaaacaagg aaaataaata aaacattaca aacaagtggt
     5821 ggaagcagtg tctcttttga tttactggcc ggagcattgg gcgacgtttt aagttctaat
     5881 gtttatgtag taagtgcaaa aggtaaagta ctaggtcttc atttaaatga tgttcaagac
     5941 agttcagtta tagaagatga gtatactaag caaaagaaat tttcagatga atatactcaa
     6001 aatgtgttaa aaattgatga aacattagaa aatttaaatg gtgagaagat attagaaatc
     6061 tttcctgaag aacatggaag attacaaaaa tatactacag tagttccaat attaggaagc
     6121 ggtcaaagat taggaacatt ggtactttca agatattcaa attcattcaa tgatgatgat
     6181 ttagtaatag ctgaatacag tgcaactgtt gttggtcttg aaatattaag agcaataggt
     6241 gaagaattgg aagaagaaat gagaaagaaa gctgtagttc aaatggcaat aggcactctg
     6301 tcctactccg agcttgaagc agttgaacat atttttgctg aattggatgg aaaagaaggt
     6361 ctacttgtag caagtaagat agctgataga gttggtataa ctaggtctgt aatagtaaat
     6421 gcacttagaa aatttgagag tgcaggtgtg atagaatcaa gatcattagg tatgaaaggt
     6481 actcatataa gaatacttaa tgacaaactt acagatgaat taaaaaaatt aaaaaacaat
     6541 caataatcta tattttatag gtttagatta gaaaaggtat ctatttcaaa tagatacctt
     6601 ttttagacga attattaagg taatgataag tatattaaaa aggagtgaga aaatgccttt
     6661 agcagataaa ataagaccaa aaacaatgaa tgatgtaata ggtcaaagtc atataatagg
     6721 taatggaaaa atattgtcta agatattaca atctaatttt ttaccaaata tgatattttt
     6781 tggtcctcct ggtgttggta aaactacagt agcggaaata atagcagaaa gaagcaataa
     6841 aagcttctat aaaataaatg ctactaattc atctttagaa gatataaaaa aggtgatatc
     6901 agagcttgga agtataaata atgtaaatgg agtcctatta tatatagatg aaatacaaag
     6961 ttttaataaa aaacagcaac aatcaatatt agaatttatg gaaaatggga gtataacttt
     7021 gattgctagc actacagaaa atccatatca ttatgtatat aaagctcttt taagtaggtc
     7081 tactgtattt gaatttaaac ctttagaaaa acttgatgta gaaaaaggac tgaaaagagc
     7141 tgttgaagta ttaaatgaag atagctatat ggatattgag tgtaataata atgctattga
     7201 agatatagca attctttctg atggagatat gagaagagcc ttaaatattt tagaagtggt
     7261 agtctattca actaaaccaa ataaggataa tataacttat atagattcag atgtaataag
     7321 ggcatctaca tttaataaaa ttataaacta tgacaaaaat ggtgatagtc attatgatat
     7381 tttaagtgca tttcaaaaat ctataagagg aagtgaccca caggcatcta tacactatct
     7441 agcaagactt ataaaaggtg gggatttgat aagtatatgt aggagacttt tagtaatagc
     7501 tagtgaagat ataggtttag cttatccaaa tgctattgta attgtaaagg catgtgtaga
     7561 ctcagctatg caacttggat ttccagaagc gaaaatacca ttagcagaag ctactattct
     7621 tttggctaca tctccaaagt ctaattctgc atgtatagca ataatgaaag ctatggatga
     7681 actggataaa gagtttgtta aggatatacc aaatagtata aaggattctc actattctgg
     7741 ttctaaagaa ataggtaggg gttgtggata caaatatcct cataatttta aaaatcatta
     7801 tgtaaagcaa cagtatttac cagatagcat aaaagatagt atttattaca taccacaaga
     7861 aaataaaact gagaaaaata taaaaaaata tttagaatat ctaaatagtg atttttagac
     7921 tgaactttat gtatcggggg tagatattat gattataaaa cttaactcaa cttatcacag
     7981 tagagttatg aaatacttaa aaaaagaacc tgagtacaat ttgtttataa taggggatat
     8041 tgaaagatat ggatatggaa ataatttttt aaatatatgg gcagatgtgg gtgaacatgg
     8101 tgaaataaag gcaatattac ttaaatattt tgaatttatg atattttatt ctgatggaga
     8161 gtatgatgtt gaaggttttt ataatctact tcgtaatact aattacgaag aaatatctgg
     8221 gaaaatatgt gctgtagatg ctttagcaaa gagattagga cttaataatt taaaggtagt
     8281 tgatttttgc aaacttcaaa ctaaaaagtt tttgatagat aataattgta atgcaaaggt
     8341 taaaagaatt aggcttggaa atctaaaaaa gacagtgaaa ctttatgact taatagatga
     8401 atttcacagt acaactttag agaatttaaa aaatggacta aggacaggta gaggatattg
     8461 tatagagatt aacaaacagg tggtgtcaat ggcaaagagt acttcagaaa ataggactca
     8521 tgcaatgata attggagtag gaacacatcc taaatataga gctaaaggac ttgctacaaa
     8581 atgcctaatt aaactatgtt cagagttact gagagaaaac aaaattcctt gtttgtttta
     8641 tgataatgaa gaggctggaa agatatataa aaaactagga tttgaaaaca ttggaaaatg
     8701 gggaatttat tcaaaataaa aaattaaaat taatcttgac aaaattagta gggtataata
     8761 aaattatctt gaaagtaatt cctactaaaa cagtatgaat tagatttcta tatagaggtg
     8821 ataatatatg aagttgtcta ctaaaggtag atatggacta aaagcaatgt ttgaattagc
     8881 attaaatcaa gacaatggac cagtatcatt aaaatttatt gctaagaagc aaaaaatatc
     8941 agatcagtac ttagaacaaa tattttcatc tttaaaaaaa tcgggtctag taaaaagtgt
     9001 gagaggtgct caaggaggtt atttgctttc aaagaatgct gaagacataa cagtaggaga
     9061 tatacttgta gtattagaag gaccagttgc attatctgac tgtgtactag atgaagatgt
     9121 atgtgaaaac tcaaacatgt gtgtaacaaa aatagtttgg gaaaagatga aaaagggtat
     9181 agaagatgtt atagattcaa ttactcttaa agatatgata aatgactata acaaaaataa
     9241 attagaaaat gatataacaa atattaaaaa atagatttgg agatgaatgt aatggaaaaa
     9301 agaagattgt atatggatta ttctgcaaca acacctatta aaaaagaagt attggatgca
     9361 atgatgccat acctaacaga ttattttggt aatgcatcta gttttcacac attcggaaga
     9421 gaagcaaaag atgctttgga taaagcaaga gaacaagtag cagcccttat aaatgctgaa
     9481 cctagtgaaa tatattttac agcaggtggt tcagaaagtg ataactggac actagagggt
     9541 gtagcttatg ctaataaaaa caaaggtaat catataataa cttcaaaaat agagcaccat
     9601 gcaatacttc atacatgtga atacttagca aaacatcatg gatttgaaat aacttattta
     9661 gatgttgata gcgaaggaaa agtagactta aagcaactag aagattcaat aaaagatact
     9721 actatactta taagcataat gtttgcaaat aatgaaatag gaactataca gcctattaaa
     9781 gaaatatccg aaatagctaa aaaacataag atattattcc acactgatgc agtacaagct
     9841 acaggtaata ttccagtaga tgttaaagaa ttaggaatag atttgatgag tatgtcttca
     9901 cataaaatat atggaccaaa aggtgtagga gctttataca taagaaaagg tgtaagactt
     9961 cataactttg tccatggtgg agcacaagaa aaaagcaaaa gagctggtac agaaaatata
    10021 cctgcaatag ttggatatgg aaaagcagca gaattagcta aggaaaatat gcaaaatcat
    10081 gtagaaactt taactcgtct tagaaataag ttaatagatg gtgtgttaga aagaatacct
    10141 tacacaagag taaatggtag cttagataat agattgccag gaaatgcaaa ctttgcattc
    10201 caatttatag aaggtgaagg aatactttta ttattagata tgttaggaat tgctggttca
    10261 agtggttctg catgtacttc tggttcatta gacccttcac atgtacttct tgcaataggt
    10321 ttaccacatg aaatagcaca tggttcatta agacttacag ttggagattt tacaacagat
    10381 gatgatatag attatatact agagaactta ccaaaagtaa tagaaagact tagaagcatg
    10441 tcaccacttt atgatgatgc gaagaaacaa ggtttagtaa aatagacata aagataaagc
    10501 ataaaaaata gacataaatt gagtaggagg aaaagataat gcaatatagt gataaagtta
    10561 tggaacattt tatgaatcca agaaatatgg gagaaattga taatgcaagt ggtgtaggtg
    10621 aagttggaaa ccctacatgt ggagatataa tgaagatatt tttagacata gatggagatg
    10681 taataaagga tgttaagttt aaaacatttg gctgtggttc agctatagca agttcttcta
    10741 tggcaactga aatgataaaa ggaaaaacta taaaagatgc attagaactt acaaataaag
    10801 ctgttgcaga agctttggat ggtttaccac cagtaaagat gcattgttca gttttagctg
    10861 aacaagctgt aaaagcagcc cttatagatt atgctcaaaa gaacaatatc catataccag
    10921 aattggatgg atatgttata gatgatgctc atgaccatga tgttgaagaa gaagaataaa
    10981 aataagtgat tgtgttatga gaagtttaca atgattaaaa agaagtacta atgatataat
    11041 taggacataa aaaatagctg tttttaaaat ggctattttt tattgcctaa attaagtatt
    11101 ttaacttgat ttagaggtta attagttaac aaaataatcc ataagattca aataataaag
    11161 atgattattt ttttagaaaa tagaacaagc tatattttaa ataagtacaa tacttgctct
    11221 atatggtata ataataagta atgcaaaaga tgaggtgaaa tttgtttatg aataaaaaag
    11281 taatgatagg tatgagtgga ggagttgata gctctgtagc tgcatatctt ttaaaacaac
    11341 aaggatatga tgtcattggt gttactatga agttgtggca agatgatgat gttgttgaaa
    11401 ttgaaggtgg ttgttgctct ttatctgctg ttgaagatgc tagaagggta gcaaataaaa
    11461 taggtatacc attttatgtt ttaaatttta gagaagtgtt taaagaaaaa gtaatagatt
    11521 attttataga tgaatatttg gaaggaaaaa ctcctaatcc ctgtatagct tgtaataaac
    11581 atataaaatt tgatgatttt tataagaagg ctagacaaat aggttgtgat tatgtagcta
    11641 caggtcacta tgcaaagata gaaaaggatg aaagtacagg aagatatttg ctaaaaaaat
    11701 ctgttacaga taaaaaagac caaacttatg cactttataa tcttacacaa gagcaactag
    11761 agcatacttt attgccaata ggtgactatg aaaaagatag agtaagagaa attgctaagg
    11821 aaatgggtat ggcagtacac aataagcctg atagtcaaga aatttgtttt gttaaagata
    11881 atgactatgc aaattatgta aaaaaacatt ctaaaaagcg tattgaagaa ggtttttttg
    11941 tagatactaa aggcaatata cttggaaaac ataagggtat attatattat actataggcc
    12001 aaagaaaagg gcttggaatt acttttggaa aaccaatgtt tgtaatagat ataaatccaa
    12061 taaataatac catagttctt ggagacaatg aagatttatt taaaaaggaa cttattgcta
    12121 aagatgttaa ctttatatca atagatacgt tagaagaacc cttaagagtt caagccaaaa
    12181 taagatattc agcaaaacca tcaccagcta ctattcatag agtaggagaa gatactatta
    12241 aaatagtttt tgatgaagct caaagagcta ttactaaagg tcaatctgta gtaatgtatg
    12301 atggagatat tgtagtaggt ggaggtataa tcgagaaaag tttataaaaa catctaaaaa
    12361 attaaaaaaa taagcaataa agtatattaa gagtaaataa agtttataaa ataaatttat
    12421 tgtatatgaa aatatagtat tgattaattt tgtaaaattt agtaatataa ttagtatatt
    12481 aattaaaaaa caaatacagt gataaggaat agtaaaatat ttgatgtctt acagagagag
    12541 ggaaatgctg gaagccctta gaatatgata tttgaagcag ccttttagta gcaatcttga
    12601 acaatttatc ttttataaag aagatttaag tagagattga cggtagttac gttatagcta
    12661 aggttttccg aagatatcat actttgtatg ataattaggg tggtaccgcg attgtcctcg
    12721 cccctataaa tttatttata gggacgaggt tttttattta aacgaaaaaa taaaatttat
    12781 taggaggaac atgatatgga aaagatggga ttaaatgaaa taagaagtaa gtttttagaa
    12841 ttttttgagt caaaaggtca ttatgtagca aatagttatt ctttagtacc aaacaatgat
    12901 aagagtttgt tacttataaa ctcaggtatg gcacctttga aaaactactt ttcaggtgta
    12961 gaagtacctc caagtgtgag aatgtgtaca tctcaaaaat gtataagaac aggagatata
    13021 gaaaatgtag gtataactgc aagacatgct acattctttg aaatgatggg taatttctca
    13081 tttggagatt actttaaaag agagtcaatc aaatggggat gggaatttgt tacagaatgg
    13141 ctaaatatac cagaagataa gatatgggtg actgtatatg aagaagatga tgattcttat
    13201 gatatatggg caaaagaaat gaatttccca gaagaaagaa tggttagact tggaaaagat
    13261 gataatttct gggaaatagg tacaggtcct tgtggtcctt gttcagaaat atattttgat
    13321 agaggagaag aatatggatg tgacaatcca gactgtaaac caggctgtga ttgtgatagg
    13381 tatttagaat tttggaacca tgtatttact caatttgata gagatgaaga aggaaattat
    13441 agtctattag aaaacaagaa tatagataca ggtatgggtc ttgaaagaat gggatgtatt
    13501 atgcaaggcg tagacactat ctttgaagtt gatacaatta aatctatact agaagcagtt
    13561 gagaagttaa caggagtaaa atatggagag aatccaaaaa atgatatatc aataagaata
    13621 ataactgacc acataagagc tgtaacattc ttagttagtg atggagtgct tccatcaaat
    13681 gaaggaagag gatatgttct tagaagactc cttagacgtg ctgctcgtca tggtaagtta
    13741 ttaggagtaa aagaattatt tttacagaaa ctaatagatg aggttataaa agtaaatgat
    13801 aaagcatatc cagttttagt tgaaaaagaa agttatatta aaaaagtagt tggaatagaa
    13861 gaagaaaaat tcaatgaaac tatagaccaa ggaacagaaa tattgaactc ttatatagaa
    13921 gtattaaaaa atgaaggaaa gactgtccta agtggtcaag aagcttttaa actatatgat
    13981 acttatggct tccctataga cttaactaaa gaaatattag aagaagaaca tctatctgta
    14041 gatgaagaag cttttaatga agaaatggaa aagcaaaaag aaagagctag aaatgctaga
    14101 ggaaatatgg atggagaaag ttggaaggaa gaccctctat caaaattaga atctacagtt
    14161 gacagtacat ttaatgggta tagtgaaatt tatggtgaag gaactattga agctatagtt
    14221 aaagatgatg agctagttca aagtgcagaa gaaggcgata aggtatctat agtactagat
    14281 aacactactt tctatcctga aggtggagga caagttggag attgtggatt gataactaat
    14341 gaaaacttag ttttagaagt attaaatact aaaaaaggtg ctaataatag tataaaacat
    14401 ataggtataa taaaatcagg aagaataagt aatggggaca aagtaaagac actcgtagat
    14461 agagaaacta gaatgtcagc tgcaagaaat cacagtgcta cacatttact tcataaggca
    14521 ttaagagaag tattaggaga acatgttaat caagctggtt ctttagtaac tccagaaaga
    14581 cttagatttg atattactca ctttgaagca atatcaaatg aagaattaaa agtaatagaa
    14641 gaaaaagtaa ataatgttat tttatcatct ttagacataa aatgtgatat tatgaatata
    14701 aaggaagcta aagaaaaagg agctacagca ctatttggtg aaaaatatgg tgatgaggta
    14761 agagtagttt ctatgggaga ttattctaca gaactttgtg gaggaactca cttgacaaat
    14821 acttctcaag taggaatgtt caaaatatta tctgaaggtg gagtagcagc aggtgtaaga
    14881 agaatagaag caataacagg aaaagctgtt tatgaatacc taaaagaaag agatggaatt
    14941 atctctgaag tttgtgtaaa cttaaaatct aaagaagata atttaattca aagaataagt
    15001 tctttattag aagaaaataa aaacttatct aaagaattgc atgatatgaa agctaagatg
    15061 agtttacaat cagttgattc tatttttgat tctaaagttg aagtaaatgg agttaatttg
    15121 ataactaata aatttgaagg tatggatatg gatacactaa gagaaacagc agataatcta
    15181 agagataagc ttggttctgg tgtagtagta cttgcaaatg tagtagatga taaagttaac
    15241 tttgtagtta ctgccactaa agatgtatta gataagggaa tacattcagg taatattgtt
    15301 agagaagttg caaaaatagc tggaggaaaa ggtggaggaa gacctaatat ggcacaagca
    15361 ggagctagtg atgtatctaa ggttgaccaa gctttaagct atgcaagtga ggttattaag
    15421 acacaagtta aataacattc actcaaggag gtttttagtt tggaaaaaga tttagactac
    15481 actatgaaat ttgaaggaat accagaagat aggatgagtg taggagatac tattgatttt
    15541 gtatataaag cattagttga aaaaggatat aaccctataa atcaaattat agggtatctc
    15601 ctttctggtg attctagcta tataactagt cataaaaatg caagagctat aattaaaaaa
    15661 tttgaaagag atgagatact tgaagaagta atcacgcact atctgaatag aaagtaggtc
    15721 aaataaatga gaaaaaagat tatgtcgttg tttgcaatag tcattatgat ttttgtatca
    15781 actgctagct atggttttgc tgaagaaaaa ggcaaggtca tatttattga tatgaatagg
    15841 accaatcttg gaagtatgat gaatattcca atcttgaaaa atgagataga aaagagaggc
    15901 tatgtagctc tcatgaatat aagaggggat caaggtactg atgatagaag gtcttgtgca
    15961 agtatgggtg caggaacaag agctagtgta actactgaag actatatcaa ttttcaaaaa
    16021 gtagaccaag atactgctaa agcttttgaa gtcgcaacag gtcaaaaagc taaagaaata
    16081 aatgatttag gcattaatag atctataaat gaaaatcttg agtatggaga atatggagca
    16141 aatttagggt cattaggaaa aactttatca gaaaatggtt taaagacatc tgtaattgga
    16201 aatgctgata taattgaaaa taatcaatta gttaaaaaca gaaacttatg tttagtagct
    16261 atggaccaat atggaaggat tgattcaggt aatattgata atattaataa gaaagattct
    16321 aaaatgccat ttggaatatc tacagattat gataaattac tagatgaaac taaaaaatcc
    16381 tataaaaata gtgatgctat atttgtagaa cttggagata catatagatt agatatgtat
    16441 agattaaatc taaatgataa tacttatgat acaatgaaga aaaatattgt aaaaaatata
    16501 aataaatatc ttgaacaagt attttctatg gttggagaaa atgacactgt ttatatagca
    16561 agtgcatttc caagtgacct agattataag aataagagaa gactttctcc aataataaaa
    16621 tttagtggag aagggaaagg tctactggaa tctgccacaa caagaaaggc tggaattgtt
    16681 gccaatttag atgttggagt agatatacta ggtacatttg gtcttgaaaa taaagagatg
    16741 gtaggtagaa gttatacttt agtaaataaa gaggacaata ttagctatct aaaatcactt
    16801 tatgaaagga tagtgtctat atcttcaata aggtcaacta ttataaatgg ctttgtaggc
    16861 gtaatatctg cttcttgggt aattgccatg tttgcgattt tctttagaaa ttatatgcca
    16921 cataaagagc gtgtattcaa agtacttaag gagtttataa aattaggcat aataatgcca
    16981 ctatcattta tgttagctcc tttgatgaat tttaaaactc caatttcaat atctttggga
    17041 atatttgcaa ctacgctaat attatacttg ttaggtagaa aattatttaa ggacaatgat
    17101 ataaagcaca tgggattttt tgcaacactt actattttag tcatagttat agattctgta
    17161 tttggaacat acttaatgca aaataacata atgagttatg atgctgtcat aggagctagg
    17221 tactatggtg taggaaatga atatgaaggt gtaactatag caagtgcagt atttggctta
    17281 gcagtattat tacattataa gaaggtatct aaattacttg ttgtaatttt ttcattaata
    17341 atacttataa ctagtgcata tccttcaatg ggtgcaaatg ttggtggagc tatatcagaa
    17401 tgtgtagcat atttgttgtt tataatgctt atatatgaca ttaaaataga ttttaagaaa
    17461 gctgtattat tagctgtttc agctgtagtt gtcgtttttg catttgcagc tttagatata
    17521 ctttcaggta gtgaatctca tttaggtatg tttgtacaga gaattttcct aaatggacca
    17581 ggagagatat tacaaacatt tggaagaaaa attcaaatga atatgcaact agcacagaca
    17641 agtgtatggg taaatatttt acttgtagga attggagtaa ttgcagtgct tatatttaaa
    17701 ccatctagac actttagaaa gataatgaat aattttccaa tcttgtttaa agggtttatt
    17761 gcatctatgg ttggttgtat aattactctt ttagttaatg attctggaat agttgctgca
    17821 tctacagcat ctatatatat acttatacca ctaataataa taagtataaa tatgataata
    17881 tttgaaaaaa ataactaaaa aaatttttac tgttcatata ggatttaaat aaaaaatgca
    17941 atatgattat taatgtaaac tggatgctta cataaaaaat catattgcaa tttttatgat
    18001 tgataatgta aaattctatg aagcagtaag cctgtgacct tagttatgag aggttcagaa
    18061 tatgtattta atctatagaa tataaataga taaaggagga actatgttag atggaagaat
    18121 aatgggtctt gatgttggtg ataaaactat tggagttgct gtgagtgatt tgatgggatt
    18181 aactgcacaa ggtgtaaaaa caataaaaag agttggcaag aaaaaagata ttgaagagct
    18241 aaaagcaata ataaaagaaa aacaagtaaa taaaattgta tcaggattac caaaaaatat
    18301 gaatggaact ttaggtccac aaggagaaaa agtaatcaag ttttgtgaat tggtaaaagc
    18361 agaaacaggt attgatgtag agttttggga tgagaggctt tctacagtag cggcagagag
    18421 gtctttatta gaagcagatg ttagtagaca aaaaagaaaa aaggttatag atatgttggc
    18481 agcagtaata attttgcaag gatatttaga ttttaaaata aattcataaa agaactataa
    18541 aattgaatac ttatgatata taatataaat aataaaaata aaaataaatt tgaggtgaat
    18601 gacattatgg aagaaaatat aataaattta atagacgaaa atggcgttga aagccaattt
    18661 gaaataatat taacattaga agcagaagga aaagagtatg caatattaat gcctttagat
    18721 gatgaagaag ctgaagaagc tttaatcttt agaattgatg aggatgaaga aggtgaaatc
    18781 ttaatacctt tggaaagtga tgaagagtat gaaactgttg tagctgtgta tactgctata
    18841 atggaagaag aaggtttaaa ttacgacgaa gatgaatcaa atggacttaa ctagataagt
    18901 aattaagttt gtatataaaa atcagatatt tattatattt gctttaatta aaccttatta
    18961 attgtaaaag catttatagt atatatctgt ttttttgttt tttattaaaa ataccaaaaa
    19021 atttatgaat tttggtgaat aatatatctt ttatgggtat atatttatat tatgagaata
    19081 aattaaattt atttaaatgt cttgacaaaa aatgaattat caattacaat attatttaat
    19141 aaagattatc aattgaaaat agtaagggtg atgttatggc aaatacaatg gatttattaa
    19201 aagacaagtt aaaagaaact ggttttaaga ttacgccaca aagaagagca atagttgaaa
    19261 tattgcttaa acatgaccat tcacatctaa gtagtgagga aatctatgat ttagttaggg
    19321 ttgactgtcc tgaaataggc ttagctactg tatatagaac aatgcagcta ttggatgaaa
    19381 taggattaat atcaaaacta aacttagacg atggatgtat aagatatgag attagtctac
    19441 ataaagaaga ctgtcataat catcatcatc ttatttgtaa aaattgtgga aagataatgg
    19501 aagctaaaga agacctttta gacaatatag aaaaagagat acaatcattg tacaaattta
    19561 aaatacttga tcatgatgtt aaattttatg gactatgtga cgagtgtaat ggagtaagcg
    19621 attcagaaga ataaacttct attgcttaat gtcgatggaa gaatagtata gaacttttat
    19681 attctatgct attcttccat tttttattat aaaccatcta taaaatgcaa atatacagtt
    19741 ttcaaagtga ttatagtttt aatattgaaa atataattaa tcctataagt acaaaaatga
    19801 atgatttttc tatgaaatta ctaaatggtc ctccaacagt taaaaaccct aaagaaattt
    19861 tcttttcgct taggggataa aaaattggta ttccttgctt tgtaaataaa tctcctaaaa
    19921 acatatggct tgcataacca atcgtaccat aaaaagataa attattaata ttagtgatta
    19981 attctatctg ttttagtaaa aaatatacta ttatagttgc aaatatgcta tgagaaaaac
    20041 ttctgtgctt taaccagggg aaaattgaca acattagaca aaaaattgta aaatatattt
    20101 caacttctat gatgtataag catatagcta atagtataaa tattaatgat agaaaaactt
    20161 ttcttagaaa tgtatgggtt agttttgctt caataattat aattgcaaca aatgtaatta
    20221 ttgcgcttaa ataaaaatta tcatttatat ttattgaaat aaagaaaata ataatattaa
    20281 cagcatatat aaaaattcta tatatgtatt tggatacatt gttttttaga atgaaatttg
    20341 agaccataga attagattta tccaaatcgg gtagtacagc aaaagtagct gaaactaaaa
    20401 tatcaactaa agatatagga attttaaata ttaaagatgt ctggatagct gttaagattc
    20461 ctattgcaca atgagtttta ccacgcataa atcctcctaa attatccgat attaaatcat
    20521 ataatattta gaggatatca aaataaaata ggtttgtcaa aataatacgt taaatgtatt
    20581 ttaaatatag cttaaaatat gatacgaatt atggtacaat aagaataact ggtagcgagt
    20641 gcgtgatttg atattattta tgattgtaga acgtgttaaa aaattaaata gacagaagga
    20701 gatgatgcaa ttgttcaaaa agaacaccaa taagataaag gtaatggcct tgggtggact
    20761 taacgaagtt ggaaaaaata tgactgttgt tgagtataaa gatgaaataa ttgttataga
    20821 tgctggactt agttttccag aggatgaaat gttaggagta gatatagtta taccagatat
    20881 aacttattta gtaaaaaata gggataaaat aaagggtata tttattacac atggacatga
    20941 agaccatata ggagctcttc catatatatt aaagaaaata aatgtacctg tatatggggc
    21001 aagacttagt ataggtctta tacaagtaaa acttaaagaa cataagatga ataatgttaa
    21061 gttaaatgtt ataggtccta gacaagttat aaagcttgat aatatggaag tagagttttt
    21121 gaaaaataac catagtatac cagatgctta ctctattgca atacacacag accaaggtat
    21181 aatataccac acaggagatt ttaagattga cttgactcct attgatggag atgttatgga
    21241 tatgcataga atctgtgagt tgagcaaaaa aggagttctt ttaatgctgg ctgatagtac
    21301 taatgcagaa aaaccaggat ttactatgtc tgaaaagact gttggggtag gtcttgacga
    21361 attatttgca aaaggaaatg gcagaagaat tatagttgct acctttgcat ccaacataca
    21421 cagattacaa caaataataa atactgctga gaagtttaat agaaaagttg ctatatcagg
    21481 tcgctcaatg gtcaatgtag ttggagttgc aaaagaatta ggatatctag atatttctga
    21541 tgacatgctt atagatttaa atgatatatg taagtatgaa gatagtgaat tagtgataat
    21601 aacaactggt tcacaaggtg aacctatgtc agctcttgct agaatggctt tttcagagca
    21661 caaaaaagta gaaataaaga gtggcgattt agttataata tctgctcatc caataccagg
    21721 aaatgaaaaa ttaatatcaa gagtaatcaa tttcttattt gaaaaaggag cagaagtagt
    21781 atacagtgat atagctgata tacacgtttc tggacatgcc tgtcaagaag aattaaaact
    21841 tatacatgca ttagttagac caaagttttt tatgccagct catggtgaat atagaatgtt
    21901 aaaaagacat gctgaaatag ctgaacagct tggtatggat aaagaaaata tttttgtcat
    21961 gcaaacagga gatgttttag aattagataa aaactctgct aaggtagcaa atcgtataca
    22021 aacaggaaac atattagttg atggtctagg agtaggcgat gtaggtaata tagttttaag
    22081 agatagaaag catttatcag aagatggtct tatgatagtt gtagttacta tttctaagga
    22141 tgagggtaaa gttttagcag gtccagatat aatttccaga ggattcgtat atgtaagaga
    22201 atcagaagat ttaatggatg gagcaaagga tataattaag aatgttctaa atgaatgtga
    22261 agagaaaaat attaaagaat gggcttattt aaagaataat attaaagaaa acctaaaaga
    22321 atatttatat caaaaaacta aacgaaatcc aatgatactt cctatcataa tggaagtata
    22381 atataaaaaa actataaatt tgaaaattag acctcttgta atttttaaag taatatcaaa
    22441 aatccaattg atattatctt aagaattaca agaggtcttt ttaatacttg atttaaaaaa
    22501 atatatatat tacataaaat accaattata acaatctttt attagtaaaa actacttata
    22561 tataaatttt actgatagga ggattcttat ggatgatgtt tcaagacaaa atgctataaa
    22621 agctttaaaa caaacaaaaa tggaaatagc aggagagtat ggaatgaatt atgaagatgc
    22681 ttttgaaata atagaaaatg cgtctaataa aggtgtttta gaaggttact ttaaaaagct
    22741 tgaaaagaaa aaaaatttag gtcaaggtat atctaggcat ttagaataaa aaaagttaaa
    22801 tgtgagaaaa taagtttaaa taaactttaa gaggtgacat cgatgaaaaa attagctagt
    22861 actgctttgg ctatattaat tgcgcttact cccttaagct tttcttttgc aaacaataag
    22921 gaaaatgctg atgccaacca actaaatata tcttcaaaat cagcaatttt gatggatgtt
    22981 ggtagtggac aaattttata tgaaaaggat gctcataaaa agcttcctcc tgctagtgta
    23041 actaaggtaa tgactatgct acttatagta gaagctttag attcaggcaa gattaaactt
    23101 gatgatgaag ttcaagtaag tgaaactgca tctagtatgg gtggtagtca aatattccta
    23161 gagccaggag aaactcaaaa ggttgataca ttgttaaaag gtatagctgt tgcttctgca
    23221 aatgatgctt gtgttgctat ggctgaacac ttagctggaa gtgttgaagg gtttgttgat
    23281 agaatgaatg ctaaagcaaa agagttaaat atgaatgata ctcattttgc aaatacaaat
    23341 ggacttccag ttgcaaacca ctatacatct gctcatgata tagctttaat gtctagagaa
    23401 ctattaaaac acgaaatgat aagtaaatac ttaactacat ggatggataa ggttgtagta
    23461 gggaagaaac aagttacagt aggtcttgca aatactaaca aacttataaa gcattatcaa
    23521 ggagcaactg gtgttaaaac tggctttact caagaagcga aatactgttt atcagcatct
    23581 gcaaagagag gtaatactca tctagttgct gcaactttag gagcagagac ttctccagaa
    23641 agatttaatg atgcctctag ccttttaacc tatggatttg ctaattatga aagtgttaag
    23701 ttatgtagta aaggtgataa tatagcaaca cttacattgg ataaggctga tgaaaacaaa
    23761 gttaaattgg ttgctaaaga agatttaaat gctcttatta aaaaaggaag ttctaaagaa
    23821 tttgagaaga aaattgaaat agtaaaaaat cctaagatgc caattaaaaa aggaactgtt
    23881 ttaggaaaga taaagatatg taaagataaa aaagtaatag gcgaagtgga attaataaat
    23941 actaaagata taaataaggc aagctatcta caaatgcttc aaagaataat tgataatatg
    24001 atataaataa ttatcagatg aaatataatt ataatacaca aagatatgat tataatacac
    24061 ataaaaaata cccttatgta attatttgcc ataggggtat ttttatttac tatatagaag
    24121 tattttataa tcttatgatt tttatagaaa tatagaaaag tttatgtatc ttaaaatatc
    24181 atttgattta atatcatata tagggttgtt taacaattat ctaagtaaag gcatactacc
    24241 agtaagttta ttcactttct ttttattccc ataaattgct atcccaaaat actgtaactc
    24301 atcttctgga acactagcaa tcttttgtgt aaattcttca taaagattgc aactttgtgc
    24361 tacatctgaa aaatctacaa cagttaaatc gttaaattcc aaagtatata attttttacg
    24421 taaatctttt attatttctt tgtttccttt taaaataggt acaggaatgt caataattcc
    24481 taagtggcta ttacctgttt tgtcaattac atctggccca acagtttctg gggcatgttt
    24541 tcctagtgta attcccatta tagctgctgt attggatata attcccattg gtaaattttc
    24601 gtctattacc atgacacatt ttgaattttt attttccatt tttatttctc ctttttacct
    24661 tatttaaagt tgtttgaatc atcatttata aatatatttt gatactgctt tggtgtaaga
    24721 ccaataaaat tcttaaaaaa gtttgtaaag tgactttggt ctacaaatcc tgtttgtatc
    24781 gcagcatcta taggttctac gcctttttct aaaagctttt tagctttgtt tacccgtata
    24841 ttttctaggt atctatatgg tgtaatacct tttaatttcg taaaattacg aagtagagag
    24901 tacttattca tacctgctat agtgcttaat tcgtcaagta ttatatgttc agcataatta
    24961 ttttctagat aatcacatac tgcttgaatt tctatatttg tattttccaa gttagattgc
    25021 aaatttggct ctgtatgttc ttcaattaat tgttcaatta ggaagaaaaa aagctcttcc
    25081 tttttaaaat ccaattcttc ttccatgatt atatagtgta attcttgtag tagaggtact
    25141 aactcactgc gaaatataac aggttgatta aattttggta aataattttt acctgtaatt
    25201 tcaaagacgg tttttttcat tatttctggc ttaatattaa tacatctgta atcaagtact
    25261 ttatcatcta tttgttcaca agtatgacta tcaaaagggt taaaaagtag caaatctcca
    25321 gtacttgtgg tatactcttt atttttacaa gataaatatc tttgaccttt ttctataaaa
    25381 ccaattacat aatgttcatg aaaatggttt gggaattttt gcattatgcc tttaaatcta
    25441 tatgcttcaa tttttaattc cctatcaaag catactgtgc gttcttcttg tctcacttag
    25501 gtaacctcct ttcatgttat acaaagtgta acacatattt ttttatactt cttgtataat
    25561 attgactaag agacaataat gtcaattcat gtcaatataa tattacactt acagtaggtg
    25621 taattattat attttcacaa tgaatatgat ataataataa aagttataaa ataaaaagca
    25681 aattttaatt ttatgcctag aagttaaaat tattataatg taaaataatt ttgattataa
    25741 gctatttaat tgttataata atattaaaaa tttaatttag gagatgtaca ttaatgttaa
    25801 gtatgaatat aggagaaata gtagcaagtt tagttggtat agctatggca atatcaatac
    25861 atgagtttgg ccatgcttat tcagctcact tattgggaga tgatacagct aaagcttatg
    25921 gtagaatgac attaaatcct gtaagacatg ttgacccaat aggtcttttg gctatgttta
    25981 tccttaagat agggtgggca aagccagtac cagtaaatcc aaataacttt aaaaactata
    26041 agataggaaa cctgatagtt tcacttgcag gcgttttttg taatgttttg actgctatac
    26101 tgtgtgtaat tatcaataag tatgtgcata tgtatgctat aaatacaata gctgaatatg
    26161 tgtttttata tagtattgga tttgcagctt ttaacttact tccgatacct ccacttgatg
    26221 gatggggagt tatatctaca tttgtaccat ataaatggaa tgaatatttg tataaatttg
    26281 aaagtatgag ttatataatt ttattaattg ctttatttac tggtatgtat agaataatat
    26341 taacaccaat atatgcagtg ttgctaaaaa tagtatattt atttgtttaa tataataaac
    26401 agattaaaga gggattgata tgaagtataa tatacaatta caagtctatg agggaccatt
    26461 agatttactt tatgatttaa taacaaagca taaaatagat ataaaggata tatccataat
    26521 agatataact aagcagtatc taaattattt gaaaatgcta gataaaatgg atttagagat
    26581 aactagtgaa tttataacta tggcatcaaa acttttagag ataaagtcta aatatctgct
    26641 ttataagcaa aaagatgaag aagaagaccc aagaatagaa cttatggaaa agttagaaga
    26701 atatagaaag tttaaggtag catcacaaga tataaaagaa aatataactt atgttaatga
    26761 gagattttat agaaataaag aagagataat tattgatgac aatgtggatt tagaagatat
    26821 atcaattgaa gcaataaaaa atatacttcc atacatattt aaagttaaaa catcacagat
    26881 agaaaatgct aatgatgaga aactagataa aatagtaagg aagaaaataa tatctgtaga
    26941 agaaaaaata ttatatataa gagatattat aaaagagaag attgaagtta cttttacaaa
    27001 tattataaaa tcatatgaaa atgatgaaat aatagctact tttttatcta tattagagct
    27061 tataaaagaa aaagaaatag tcgtagtaca agatatattt tttgatgata ttctaataag
    27121 aaaaagttcg gagtgttaaa atgaaaagag aagatataaa gtatattata gaatctgtta
    27181 tgtttgcata tggtgagcca ataagtataa aagaattaaa ctatataata aataaagaac
    27241 tttcatcaaa agaaatagag attatgttaa atttacttat tgaggagtac agagaacaaa
    27301 atagaggtat tcaaataatc aagttagaga ataagtacca aatgtgtaca aataaagact
    27361 atgcagaata tataaagaag attattgaac caaagaaaaa gaaaagtttg agccaagcta
    27421 cattagaaac tcttactata attgcctaca aacaaccaat aacaaaggta gaaatagagg
    27481 atataagagg agtaaaatgt gataaggtat tacaaacttt gtttgaaaat gaacttataa
    27541 gagaagctgg tagattgaat aagataggga aaccaataat ttataaaaca acagatgaat
    27601 ttttaaagtt gttgaatata gaaagtcttg aagaattgcc acctatagaa aattatcaag
    27661 aagtggcaac aaatgaataa aaatataaaa tcacaataat ttagtatgta attttaaatt
    27721 ttaaaagatt taaaatgctc taagttgttg tgtttttttg tataaatata aaattataat
    27781 tctcttaaaa taaatatgga taattaagta taaatagtaa ttttttgatg ataatataaa
    27841 catggagctt aatgaattat ttaattttaa gtatttaata atagctgtaa tttttattat
    27901 aagtgtaact atgttgattt taatatctca tataaacatc ttaataatag ctgatataaa
    27961 aaacaaagat atttgtttaa agcttaatat aaaatacatg tttaatttaa taaatataaa
    28021 tagacaactt tatccagctg aaaatagtaa aaataatgat aaaaaagagg ggatgaagaa
    28081 taatatagat tcaagtatat tattagctga tgaccttttg agcatttata gattattaaa
    28141 aaagataaaa atacatgaac tttattcaaa tattaatttt ggaactggaa atattggctt
    28201 aacatcttct gtatatgtat tgataaatac tttgtatgga aatttattta atatgattga
    28261 tgcagaaaaa atgtatttaa atgtaaatcc agattttaca aaagattatg ttttaggaaa
    28321 tataaggata catataaggc caagaataaa agctttattt aatattataa taatgattaa
    28381 taaaattatg aataaaaata aaggaaataa ggaaggtgat agtaatgaga gcaacaggtt
    28441 cgatacagag tcttatggaa acaactcttg aaacaattaa aggttctata gatgcaaata
    28501 ctattatagg agaccctata aaaacagata ctacagtggt tgtacctata tcaaaggtta
    28561 caattggctt tggtatagga ggaggagaat actcaaaagg atatgatgat aaagataggg
    28621 aaattgaatt aaaaaatgaa aaatcagata cgaattttgc tggaggtagc gcaggggcta
    28681 tatctgtaca accagtagca tttgtagtag ttgaaagtgg agagactaga ataatgagtt
    28741 tagacagtaa tatcaatcta gtggataata tattatctat aactcctaga gtattggaga
    28801 aaattcaaaa tatatcacaa agtaataaga atcaagataa aaacaatatg taagaataaa
    28861 atatttttaa atatgtatat agttttaggt aaagtagtgg ggttagtata aatcccacta
    28921 ttttgttgtg tactttaaac atttatatct aataagattt tagtttaaaa caatttaaat
    28981 agataataaa gttgatatat agtataatta taaaaagaaa agaagtatta tattatagat
    29041 atataaacgc atttgagata taagagggag ttataaatca ttagttttga ggtgaatgtt
    29101 atgagcgata aagaattatc tattttgttg ttagaaagta tgaataattt tcataattta
    29161 ataaagatta ttaataacga aagatataaa aaagataagg ttcttacaga aagacagttc
    29221 tttgccttag taaaaataag aaaacatgat aaaatagagc ttaaaaatct aagtagagat
    29281 ttgcatgtat ctacttctag tctgtgtata ctacttaata aattggttga gcaagagtat
    29341 gtatataggg aagaagatag tagagataga cgaaatactt tttatggaat aactaaaaat
    29401 ggagaaaaga tattggataa tgaaatacta aagtttgtat ctataataag tgataaaatg
    29461 gattgcctag atatagataa taaagataaa ttatttactt ctttggaaga gtctaaaaat
    29521 ataatagaac aattatttta aaaaggagaa tttattatga atataaagta ttctaaagaa
    29581 atattaaaaa gtttagaaaa tgctataaca gtagtagctc tatttgaggg agaagatgtt
    29641 tctacgacat ttgataaaat aaatatgata agcagaaatt ttaattctaa agaaaatagt
    29701 atagatactg taacattgat tgaaaataac aatttggtaa atgtttgtct tgttggtttt
    29761 ggtaagagag agttattgaa tagagaaaaa attagaatca taggtggtaa tttgtgtaaa
    29821 aaattaaaaa atatattgaa aaatgaagca tataagagta gtgatgttaa tgtactgaat
    29881 cttaatttaa atagtgatga aataggttct tttgtagaag ggatattact tggaaattat
    29941 aagtttgata agtataagac aaaaattaag gattttgaaa gaaaagaagt tgatactata
    30001 actatattta ctgaaaaaga agttgagtgt caaatagaaa aggctaaaat attagctaat
    30061 tcaactataa tagctagaaa tctagttaat gaaccatcaa acgtaatata tccaaaaaca
    30121 ttagcagtag aaacagttaa acttggtgca gagtttgggt ttaatgttga tgtttatgaa
    30181 gaagaaaaaa taaaggcatt gggaatggat gcttttttcg ctgtttcaag aggctcaatt
    30241 aataaaccaa gattcatagt aatgagatac tttggagata aagaaagtac agatatatta
    30301 ggtttagtag gtaaaggatt gacttatgat actggtggat attctttaaa atcaaatgct
    30361 tctatgctag atatgaagac agatatggct ggtgctgcga gtgttatagg tgctatgtgt
    30421 gctatatctc aaagtaaatt aaagaaaaat gttatagcag tagtggctgc atgtgagaat
    30481 gctttatcag gaggttcata caaacctgga gatataatta gttctatggc aaagaaaact
    30541 attgaagttt taaatacgga tgcagaaggt agacttacat tagctgatgc aatatactac
    30601 attataaaca atgaaaaagt aacaaaggtg gttgatgtag ctacattaac tggtgctgct
    30661 ttaacattgt taggtaatgt tgcaactcct atagtaacaa ataatgatga tttttattgt
    30721 gaattagaaa aagctgccac tttatcaggg gaaagggtat ggaagatgcc aatttatgat
    30781 gaatttaaag atatgataaa aggagaagaa gcagacctta aaaacactgg tggtaaaaat
    30841 gctggatgta taacagcagg agcttttatt ggtgaatttg ttgggaatac tccttggata
    30901 catatggata tagcggggac aagtacatca tcaaaatcaa ttggatacaa agcaaagggg
    30961 gctacaggag aacctgttag aacattgtac tatttggcag aaatctaaaa aacaattata
    31021 aaatataatt tataaagcca cgtggatatt tttgtaattt aagattatct atgtggcttt
    31081 attttttatt taaataaatt atttactctt tttctttttt tcaagtataa aagtatctct
    31141 attaaataaa agagcaggta tgtacataat actagtaaca aaaataaacg taaaaatagc
    31201 agttgtgcta tgacttaaaa aaccataata gtacctagag ttggtgaatg tgtttagtaa
    31261 aaatatgaat gaaaaataaa taaaacatat agctaagtta tctctaagtg catatctgtt
    31321 aactctaaat tttctaacat caaccatata tatatctgca taaattatca agcacttaga
    31381 gaagataaag ataaaatata ttaagctagg aaattcatag cccaagtttt tagaaaaaat
    31441 gagttctcca actgaacaaa ctaaactcca agaaaaaaat atattaaaaa gatgatactg
    31501 cttaaaaatt agtatggcta tacacagata tatacaaata taattgattc caattggtaa
    31561 agagtttaga gtactataat tacctgaaga aataagtaat aattgctcta gagccataat
    31621 tattacaagt aatgtacaaa ttatcttctc aactgtatag ctataaggta aaatattttt
    31681 ggttagtttt ggacaatagt ataaaaataa tccaaatata aagagactta caaattgttc
    31741 actagaaaaa agaaaaattt taaacatata acattctctc ctataataaa tttaatatgt
    31801 atctatataa atatattcat ta
//
LOCUS       DAMJVG010000045        31482 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.045, whole genome shotgun sequence.
ACCESSION   DAMJVG010000045 DAMJVG010000000
VERSION     DAMJVG010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 31482)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31482)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31482
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.045"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(125..694)
                     /locus_tag="PC512_002217"
     CDS             complement(125..694)
                     /locus_tag="PC512_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDF2441957.1"
                     /translation="MIIIYGYCRVSTKNQTDNNSLYQQQQEILNKYNDAKIIKETYTG
                     TTTNRPKFEKIISSLKKGDLLVATKLDRLARSTSEGIQLIEGLFAKEVSVHILNIGLL
                     ENTSMGKFFLTTLLAVAELERNMIIERTQLGKEFAKKKKDFKDGRPKKYSNQQIQYAL
                     GLLNSKPYREVVKMTGISKSTLIRAKKSI"
     gene            897..1124
                     /locus_tag="PC512_002218"
     CDS             897..1124
                     /locus_tag="PC512_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDF2441958.1"
                     /translation="MNSLLKEAIDELKNIHCGEVFLLKELFKGYEWNRLEMNIRLKLG
                     KLFLYEVVTNPNLNVEVINKNSAYQQMYKKK"
     gene            complement(1343..2086)
                     /locus_tag="PC512_002219"
     CDS             complement(1343..2086)
                     /locus_tag="PC512_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HDF2441959.1"
                     /translation="MENYQSTNTCTYNILYVQFNEDFERSKYFSYDVKYPVIYNIRNQ
                     STYVNPVILNNINNAVRMTVNNFKNGLQEEEREYNNATSQNSLPKQSYWVSTSYAVTF
                     NKNYVLSMILNLMGFANNYGPKYNTLNNYNIDLTTGKELLLNDIFRDGVDYINIITDY
                     IKSQINENREMYYSNVELVIPEDQAFYLTDNGIIIYFGVDEIAPESFGIPKFELKFSD
                     FGNFINLRFYCISPDIYVQSRGRAKHFMG"
     gene            2254..3126
                     /locus_tag="PC512_002220"
     CDS             2254..3126
                     /locus_tag="PC512_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDF2441960.1"
                     /translation="MLLLADKWKDYELIDMGNGEKLERWGSYVLRRPDPQVVWPMESE
                     WALWKNPHGHYHRSNKGGGQWEHKKRYPEQWTINYKNLKFHIKPTGFKHTGLFPEQAA
                     NWDWMIEKIKKANRPIKVLNLFAYTGGATVACASAGAEVCHVDAAKGMVNWAKENIEL
                     SGLKNQTVRFIVDDVVKFVEREIRRGKKYDAIIMDPPSYGRGPKGEVWQIEEKLYSFV
                     DLCMGVLSDNPLFFLINSYTTGFSPIVLENVLSTTIGKKTNTGDIYGGELGIPASRDG
                     KILPCGIFGRWEKK"
     gene            3126..3791
                     /locus_tag="PC512_002221"
     CDS             3126..3791
                     /locus_tag="PC512_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HDF2441961.1"
                     /translation="MIKVIYEDNHLLVVEKPVNILSQGDNTNDKDMVNLLKDYIKKKY
                     NKPGNVYIGLIHRLDRPVGGVMVFAKTSKAASRLSEQVRSKTFKKTYLAVVHGKIKSN
                     SDILKDFLYKNKKTNMVTVVKKSHKDAKEAELNYNVLDFKENLSLVQVNLKTGRSHQI
                     RVQFASRKHPLYGDQRYGKEINKIGQQISLWSNKIEICHPTTKEKMEFTCHPPDKYPW
                     NIF"
     gene            3812..4669
                     /locus_tag="PC512_002222"
     CDS             3812..4669
                     /locus_tag="PC512_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2441962.1"
                     /translation="MSKKFSIGEMSKLHKISIQTLRYYDQIDLFKPVHVDQESNYRYY
                     SIDQFSQLDIIKYLKYLGMPLKEIKSKLDENNEEILKLLTNKINIVDEKIKELELIKK
                     VLSTKKETMEKGMKVDEVGKIVRKHIPRRSILSIEYEEGLSSEETMELSRRQIANILE
                     DNISVFYGGVSGLVSIDKFLKEDKVIYDNSFVTVERDLFDIKSQKHITEISSGDFICM
                     TYKGPYKENYTAFKKLVDYVEYKRIPIENYIYEIPIIDPLSTNNEEELLTEIQIQVKK
                     REIDLRCLV"
     gene            complement(4825..7371)
                     /locus_tag="PC512_002223"
     CDS             complement(4825..7371)
                     /locus_tag="PC512_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDF2441963.1"
                     /translation="MNIFNKVALQGLKKNRTRTLVTIIGVVLSAAMITAVTTFGVSLM
                     NYMTNGAIIKYGDWHVQFLDVDSSFVQEQRVNDEVANTATFENIGYATLEGNRNPDKP
                     YLFIAGFSKEAFDTLPITLISGRLPENSREILVSSKVATDGGVKFAVGDTISLDVGKR
                     MSENEKLGQSDPYTAGSEVFVPQDKKTYTVVGICRKPVFEESSAPGYTLITKEDKQVK
                     TDSLSLFVTLKNPHQIRSYISSTKDHASIFNDNVLRFIGVSDNNLFNMFLYSVGGIVL
                     AIIMLGSIFLIYNSFNMSLNERTHQFGILSSVGATAKQLRNSVLFEGICIGAIGIPIG
                     VAIGIVSIGLVISVIAKNFANILYVNVPLTLTLSIPAIIVAAVVSMVTILISAYIPAR
                     KAANTPVMECIRQTNEVKIESKSVKTSKLTQRVYGLEGVLAMKNFKRNKKRYRSIVLS
                     LVLSIVLFISTSALVADLKQMSNQRSEVTDQDIIFSTQGMKDNEMLKLYDKLKTANGV
                     YEGLYQKLMTYSCVAKVSELTDDYLNYEGSHSMSEMLELPVDMQFLDDRTYLNIIKSL
                     GLPAEEYTGQNAKLIAVSMVTKDNNIIDIFNSSSMNVSLTPETNGKLEIPERQNVNIS
                     FVKVVPPDSPPGIRSSDVKKASFRVLAPYSAKDKFEIPGVSTGIESLSFQSKNPTQSV
                     AEMEQIIESEGVTNEYNLYNMYGMMDENRNYIFIANVFAYTFIIMISLISIANVFNTI
                     STNIKLRRRELAMLRSVGMSEHDFQKMMNFECAFYGMRALFFGLPIAVISSWLIHKVM
                     VTDDIDFVIPWFSIGISIFSVLFIVFITMLYTINKIKKENIIDALRDDMA"
     gene            complement(7371..8057)
                     /locus_tag="PC512_002224"
     CDS             complement(7371..8057)
                     /locus_tag="PC512_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2441964.1"
                     /translation="MAFLKIEDLCKVYGKNENKVTALDHVSLTIEKGEFTAIIGSSGS
                     GKSTLLHSIAGVDVPTSGKIYLEGQDVYGQSNEKLAIFRRRQVGLIYQFHNLIPTLNV
                     VENITLPILMDKRKVNQERLNDLLELLGLKERKTHLPNQLSGGQQQRVAIGRALMNAP
                     AVMLADEPTGSLDSKNGQEIIQLLKESHSKYHQTLIIVTHDENIALQADRIICISDGK
                     VVRDERKVNR"
     gene            complement(8140..9129)
                     /locus_tag="PC512_002225"
     CDS             complement(8140..9129)
                     /locus_tag="PC512_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2441965.1"
                     /translation="MFRNREFRKFAILFLLITILTVALGFAISIMTGILSIVSATTFG
                     IAFFVFTKNRYKSIAQISEQINLVLHNANHLYIAESDEGELSILQSEITKMTLRIREQ
                     NYALKKEKEHLADSLADIAHQLRTPLTSVTLILSLLENTSDEDERKELIRETEELLIR
                     MDWLITSLLKLSRLDAGIVVFQKEQIDVNNLISSALHQLLIPMELHNITLHIDIPKGV
                     RILGDLNWLSEAIQNIFKNCMESVGDNGKIDIICEDNFLFTQLTIHDNGAGFKKEDLP
                     CLFNRFYRGKNSSTAGYGIGLALCKTIIMRQGGTITAQNHPQGGAIFVIRFPK"
     gene            complement(9116..9802)
                     /locus_tag="PC512_002226"
     CDS             complement(9116..9802)
                     /locus_tag="PC512_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2441966.1"
                     /translation="MKRIFLVEDDKAIAKNLILLLNSEGFIVTHVSTRSEALVEIAKN
                     KFDLALIDISLPDGNGFTICTEIKEKQDIPVIFLTASGDESSVVTGLNMGADDYITKP
                     FRPRELIARIRTALRKSGRFGSTFEICGLYVDTATGVVKKNGNEVFLSALEYRLLLVF
                     ISNPKSIITRVRLLDELWDAAGEFVNDNTLTVYIKRLREKIEDDPSSPQIILTVRGTG
                     YRLGGSYVSK"
     gene            complement(10302..13508)
                     /gene="carB"
                     /locus_tag="PC512_002227"
     CDS             complement(10302..13508)
                     /gene="carB"
                     /locus_tag="PC512_002227"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HDF2441967.1"
                     /translation="MPKLDSIKKTLVLGSGPIIIGQAAEFDYSGTQACQALKEEGIEV
                     VLVNSNPATIMTDKEIADKIYIEPLTIEFIEKIIEKEKPDSLLAGMGGQTGLNLAVEL
                     HDAGILDKYNVKVIGTSIESIKKGEDRDLFREVMKEINQPVIVSDIVTNLEAGLEFAN
                     KIGYPVVVRPAYTLGGTGGGIADTEEELREILSHGLQLSPVGQVLLEKSIKGWKEIEY
                     EVMRDGNGNCITVCNMENVDPVGVHTGDSIVVAPSQTLSDEEYQLLRKASIDIINAIE
                     VQGGCNVQIALNPHSLEYAIIEINPRVSRSSALASKATGYPIAKVAAKIALGYTLDEI
                     ENAVTKKTYACFEPTLDYVVVKIPKWPFDKFRHANRKLGTKMMATGEIMSIGSNFEAA
                     ILKGIRSLETGKYSLVHAPSEGRTLEELKARVVVPDDERLFDLAEMIRRGYKVEMISE
                     ITGVDKWFINKFKWIVEQEEKLKVLKIEDLDKEYLHELKKKGFSDKGISDLMKISPEK
                     LYELRSLYNIQPVYKMVDTCGGEFEALSPYYYSTYEQYDEVVVSDKRKVVVLGSGPIR
                     IGQGIEFDYCSVHCVKSLRKMGIETIIVNNNPETVSTDFDTSDKLYFEPLTEEEVLNI
                     IEKEKPEGVILQFGGQTAIKLAKFLHEKNIPILGTDFRDIDAAEDREKFDDLLERLDI
                     NRPKGKGVWTTNEGVEIAKELGYPVLVRPSYVLGGQGMEITYNEEKLIQYLDDAFDRD
                     HKNPVLIDKYLTGREIEVDAICDKEDILIPGIMEHLERAGVHSGDSTTMYPSQNISDE
                     IKEKIVEYTKKIALDLNVLGMVNIQFIEFQNELYIIEVNPRASRTVPYISKVSGVPIV
                     DLATKCMLGAKLKDLGYSTGVYKEPKLVSVKVPVFSMSKLSKVEVSLGPEMKSTGEVL
                     GVGENLEEALYKGFLAAGRHMSDERGVVLATVNNHDKDEFIEIAKDMKELGYTFVATE
                     GTAKSLRENGIEADIVNRIEEPRPNILDAIRNKQVDIVINTPTKGNDSTRDGFKMRRT
                     AIEFSTEIMTSLDTLKALVEVKKKHLNKDKLKVYNIAE"
     gene            complement(13701..14750)
                     /gene="carA"
                     /locus_tag="PC512_002228"
     CDS             complement(13701..14750)
                     /gene="carA"
                     /locus_tag="PC512_002228"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002845470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HDF2441968.1"
                     /translation="MKARLILEDGTVFIGKAFGYLEESVGEVVFNTSMIGYGEVLTDP
                     SYYGQIVTMTYPLVGNYGINLSSAESEKVQVKGFIVREKSDSPSNFRCEIDIDQYLKQ
                     NKVIGLEGIDTRALTKILRNNGTMKGIITLEDSKLEDVKHKLDKFSNTEAVRTVTRKE
                     VEHIKGNGPKVAVMDFGVKRNILRSFIARGCDITIFPATTSPEDVLSINPDLIFLSNG
                     PGDPEDLEDVIENIKALIGKKPIVGICLGHQLLALALGGKTAKLKFGHRGGNHPVKDL
                     EEGKVFITSQNHGYYVSEVPEQMKVTHINLNDNTVEGMRHEKLDVYSVQYHPEACPGP
                     KDNDYIFDKFLELVK"
     gene            complement(15007..18213)
                     /gene="carB"
                     /locus_tag="PC512_002229"
     CDS             complement(15007..18213)
                     /gene="carB"
                     /locus_tag="PC512_002229"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HDF2441969.1"
                     /translation="MPKLDSIKKTLVLGSGPIIIGQAAEFDYSGTQACQSLKEEGIEV
                     VLINSNPATIMTDKEVADKIYIEPLTIEFIEKIIEKERPDSLLAGMGGQTGLNLAVEL
                     YEKGILDKYGVKIIGTSVESIKKGEDRDIFREVMKEINQPVIVSDIVTDLQAGLDYAL
                     TIGYPVVVRPAYTLGGTGGGIADNEEELREILSHGLQLSPVGQVLIEKSIKGWKEIEY
                     EVIRDSKGNCIVVCNMENIDPVGVHTGDSIVVAPTQTLSNKECAMLKKASLDILNAVE
                     VQGGCNVQFALNPHSFEYAVIEINPRVSRSSALASKATGYPIAKVSSKIALGYTLDEI
                     ENAVTKKTYACFEPTIDYVVAKIPKWPFDKFKKANRKLGTKMMATGEIMSIGSNFEAA
                     ILKGIRSLETGKYSLVHTPSEERSIEELKKRVVVPDDERLFDLAEMIRRGYKVEMIEQ
                     ITGIDKWFINKFKWIVEQEEKLKVMKIEDLTKDYLLELKKKGFSDKGISDLMKISPEK
                     LYELRSLYNIKPAYKMVDTCAGEIDAISPYYYSTYEQYDEVVVSDKKKVIVLGSGPIR
                     IGQGIEFDYCSVHCVKSLRKMDIETIIINNNPETVSTDFDTSDKLYFEPLTEEEVLSI
                     IEKEKPEGVILQFGGQTAIKLAKFLHEKNIPILGTDFDDIDAAEDREKFDDLLERLDI
                     NRPKGKGVWSLNEGIEVANELGYPVLVRPSYVLGGQGMEITYNEEKLSQYLQDAFDRD
                     HKNPVLIDKYLTGREIEVDAICDKEDILIPGIMEHLERAGVHSGDSTTMYPSQNISDE
                     IKEKIVEYTKKIALDLNVLGMVNIQFIEFQNELYIIEVNPRASRTVPYISKVSGVPIV
                     DLATKCMLGAKLKDLGYGTGVYKEPKLVSVKVPVFSMSKLSKVEVSLGPEMKSTGEVL
                     GVGENLEEALYKGFLAAGRHMSDERGVVLATVNNHDKDEFIEIAKDMKELGYTFVATE
                     GTANSLRENGIEADIVNRVEESRPNILDAIRNKQVDIVINTPTKGNDSTRDGFKIRRT
                     AIEFSTEIMTSLDTLKALVEVKKKHLNKDELKVYNIAE"
     gene            complement(18266..19309)
                     /gene="carA"
                     /locus_tag="PC512_002230"
     CDS             complement(18266..19309)
                     /gene="carA"
                     /locus_tag="PC512_002230"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HDF2441970.1"
                     /translation="MKGKLILEDGTVFEGKAFGYLKEAIGEVVFNTSMAGYGELLTDA
                     TYYGQIVTMTYPLIGNYGINLEDVESNKVQVKGLIVREKSDNPNNFRCEMDIDTYLKQ
                     NKVIGLEGIDTRALTKIIRNNGTKRGIITLENVSLQDVQSKLEEHCNKDSVKNVTRKE
                     IENIKGTGAKVVVIDFGVKNSVLESLKACNCDITIVPAMTTVEEILNINPDLILLSNG
                     PGNPEDINDIVENIKKLIGKKPLTGIGLGHQILALALGGKTSKLVFGHRGGNHPVKCL
                     ETGKVFITSQNHGYNVSEMPENTEVTHINLNDNTIEGMRHKELPIYSVQYIPEYTTKE
                     DLDCIFNKFLALI"
     gene            complement(19335..20051)
                     /gene="pyrF"
                     /locus_tag="PC512_002231"
     CDS             complement(19335..20051)
                     /gene="pyrF"
                     /locus_tag="PC512_002231"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HDF2441971.1"
                     /translation="MINGKEKLIVAIDTDEFDKAKELIDRLEDSVDIFKVGLEQYVAT
                     KGKTIDYLKEKGKKIFLDLKFHDIPNTMKSAVKAAVRDNVWLMTIHVSDMEGMRQCAL
                     IAREEAERLNIEKPLVVGVTVLTSLSNQDLQDIGCNMTTEELAIKRAKLAKESGIDGV
                     VCSAQEVDKIVEACGTDFITVCPGIRPKSAEVGDQKRVVTPSDAIKKGAHYLVVGRPI
                     TKAENPRESAINIVREIENA"
     gene            complement(20427..21062)
                     /locus_tag="PC512_002232"
     CDS             complement(20427..21062)
                     /locus_tag="PC512_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1847 domain-containing protein"
                     /protein_id="HDF2441972.1"
                     /translation="MYKCGKCNLRGCSNGNMDKLMKICPTREIELQQKAKQLYEEEEN
                     RKIAYNAGLVEAEGYCQYTRLKEIIEFAKKCGYKKIGIAFCIGLKREMQTVQKIFEHH
                     GFEVFSVICKNGAMPKSTIGLEASQTISKCSDEVMCNPIGQALFLNEAKVDLNVILGL
                     CVGHDTLAMKYMEAPITTLVVKDRVTGHNPVAAIYNAESYFEKKLFDKDEE"
     gene            complement(21086..22000)
                     /locus_tag="PC512_002233"
     CDS             complement(21086..22000)
                     /locus_tag="PC512_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441973.1"
                     /translation="MELYEAIFYRKSVRNFSSKKIKKPLMEEIKRSCKNLEYLNEDLN
                     IKAHVVDRGHIIHFLMGKECKVKAPHYIVVTSDKGEDYLQNIGFATEGVVLRLTTLGI
                     ATCWLEGNLKREDILEFVDIGNKNFEEDEEDDLDYLAGIKTEEDDENKIENPYIIIAF
                     GYPAKNEELFRTRYARPDRKPVKDMINKINRNRKWKDILELTRRAPSVKNSQPWYFHK
                     DERGLHLFEKRPKKHCEDMNKVSLGVALRHFDIACIKNKIDVSYEKLPIRNKIGKSYF
                     ITVVEHVKPEEETQEENVTLEKEESQDE"
     gene            22601..23830
                     /locus_tag="PC512_002234"
     CDS             22601..23830
                     /locus_tag="PC512_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HDF2441974.1"
                     /translation="MNLNRNLEKYAELAIKVGVNIQPGQILLIKSPIECADFARNALK
                     EAYKCGAKNVYIEWSDEESTLIKYLYAPDEAFHEFPKWTAEQYVDIAKEGGAFLSVYA
                     QNPDLLKDVDPERVANFQKASGKALKEWRSYTLTDKCKWNIVSVPTKDWAKKVFPNLS
                     EDKAIEKLWDAIFKCSRVDGQDPIKAWEEHNENLKSKMDFLNKNNFKTLKYKSSKTDL
                     TLDLPKGHVWLSGASKDPNGISFNPNIPTEEIFGMPHKFKVNGTVYSTKPLVYGGNII
                     DNFFLTFKDGKIIDFSAEKGLDTLEKLIETDEGSHYLGEVALVPYNSPISNTDIIFYN
                     TLYDENASCHFAIGSAYKTCLEGGNNLKDEELDEHGVNDSLTHVDFMIGSADMDIIGE
                     TYDGKQIQIFKNGNWAF"
     gene            complement(24035..26416)
                     /locus_tag="PC512_002235"
     CDS             complement(24035..26416)
                     /locus_tag="PC512_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homocysteine S-methyltransferase family protein"
                     /protein_id="HDF2441975.1"
                     /translation="MEIRQYLKNNILIFDGAMGTMLQQKGLKLGENPEVFGLQNPDKL
                     IEIHTAYLEAGSNVILTNTFGCNELKLDSKYTVEEVIDNAVLVARKAIENVDNTKPRY
                     VALDIGPIGEMLEPMGTLSFDKAYEIFKRQVLQGVKSGVDVIVIETMMDLYEAKVAVL
                     AAKENSDLPIFCTMTFDEGGRSFTGCMPECMVATIEGLGVDAIGVNCSLGPKQLLPIV
                     EKIASRATVPVMVQANAGLPNIVDGEAIYDVDAKEFFEGVKKFVEVGATIIGGCCGTN
                     PSFIKEISENINSVTKGCIEKIDKCVVCSPSKFVEVQSPTVVGERLNPTGRKSLQEAL
                     KNENVDYAINLGLEQVNAGAQILGVNVGLPEIDEKKLMPKLIREIQAVVDTPLQVDSS
                     NVEALEQGLRYYNGRTIVNSVNGKEESLESILPIVKKYGSCVVGLTLDEKGIPKKAEE
                     RFEIAKRIVNRAVSYGIKPKDIFIDCLSLTVSAQQEEAIETIKAITMVKTLGVKTILG
                     VSNISFGLPNRKALNASFLTLALGAGLDLAIINPNEYSMMEAINSFKILNNTDKGCIN
                     YINQYSNINNSKKSDSSTKIDKDLPLDILVERGLKDEAKNVTLNLLKEKDENYILDEI
                     LIPALDKVGKRYDSGDIFLPQLIQSAETVKVSLNTIKETLLSKSSNNVSKGKIIVATV
                     KGDIHDIGKNIVKIMLENYGYEVIDLGKDVPIEEVVEVAKKRNIKLVGLSALMTTTVQ
                     SMKDTIQALRDNEINAKVFVGGAVLTEEYAEEMGADYYSKDAKSAVEIAKLNF"
     gene            complement(26388..27113)
                     /locus_tag="PC512_002236"
     CDS             complement(26388..27113)
                     /locus_tag="PC512_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Vitamin B12 dependent methionine synthase,
                     activation domain protein"
                     /protein_id="HDF2441976.1"
                     /translation="MENNLIGREDISINQSEVLRYLQYRGQEIDKDLKYTIDECVAIT
                     KNKINPRYLSRIYPIRINKDNVVELEGTNLTLESKYVYELLKECNECVIMAATIGIDI
                     EKEIRRHSYSNLTKGLIIDSCGTTAIEEVCDIVQNNLEKVFLKQDKFITMRYSPGYGD
                     LPIEKNIDILNVLNAQKQIGLTITSNGIMIPRKSVVAIIGISNTRINKSKKEKSCENC
                     KNYRNCTYRKGANSCGNKTISEK"
     gene            complement(27103..27558)
                     /locus_tag="PC512_002237"
     CDS             complement(27103..27558)
                     /locus_tag="PC512_002237"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HDF2441977.1"
                     /translation="MEKVESFKLDHTKVKAPFVRKCSVLDGVKGDKVTKFDLRFLQPN
                     VESFGTAAMHGLEHLLATYLRDTLDGVIDLSPMGCRTGFYLILWGDVDAKTVKIGLEE
                     ALKKVLESDKMPAATAIECGNYRDLSLFGAKEYAKDVLDKGFSLNIYGE"
     gene            complement(27840..29021)
                     /locus_tag="PC512_002238"
     CDS             complement(27840..29021)
                     /locus_tag="PC512_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDF2441978.1"
                     /translation="MKNKSLLNHMFRPILDLIISCALTSMLILTSMYIIKSLYVNSDM
                     SVVNQLVYQARDFRSLIGYDLFYPFLFTITSLAIYSIISYKRNKQIVDFIRKTNRKNQ
                     KLEIIKSAVNLMDEGNLEKSIDIEYDLDILKDKEKDDIDELAHKINNIVHQLRNITIE
                     ERQAQQTKTDLITNVSHDLRTPLTSIMGYLGVIEEGKYKDEVQMMYYVDIAYEKSKNL
                     NVLINDLFELTKMQNNTIKLNKIEINLVELLSQVVSQFEIYFKQEFMVSRINFNEEKL
                     IVKADPNKLVRAFENLITNAVKYGKDGHYVDIVTEKKEDMAVVKVINYGEPIPVLDLP
                     NIFDRFYRVEKSRNRNVGGSGLGLAITKNIVNLHDGEITVSSDKYQTVFEVQLPIIQS
                     A"
     gene            complement(29011..29703)
                     /locus_tag="PC512_002239"
     CDS             complement(29011..29703)
                     /locus_tag="PC512_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2441979.1"
                     /translation="MNNTVLVVDDEKEIRDLIEIYLLNSGYNVIKAEDGKEALDILKK
                     ENIHLMILDIMMPKMDGIEVCRKVRESLNIPILMLSAKSEDMDKIQGIMTGADDYLTK
                     PFNPLELTVRVKSLIRRAYYFSGANNEDKDVIKVGVVIIDKEKHSVTVAGNEIILTSR
                     EFDILYLLANNKGRVYSTEEIFEKVWKEKYYQSNNTVMVHMSRIRDKIEKYTDGEKII
                     HTVWGVGYKIEK"
     gene            complement(29837..30553)
                     /locus_tag="PC512_002240"
     CDS             complement(29837..30553)
                     /locus_tag="PC512_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HDF2441980.1"
                     /translation="MKKFKLIGAIILVVFISVFISKDRLLKKDKDPIVAAQHDSEQDV
                     EANSQNKNHSNSISNILLVNKTNGISKNYTPENITKVNIPFVEEATEEEKQMAGEPAK
                     AVEDLVKQANSEGIQFLGSSAYRSYDTQLDTYTRRVKSQGREKADAYVAKPGYSEHQT
                     GLCIDLTNPERWFVGSTKEAKWLAENAHKFGFIIRYPEGKEDITGTAYEPWHIRYVGK
                     DAAEEIYSKGLTLEEYLQNK"
     gene            30678..31412
                     /locus_tag="PC512_002241"
     CDS             30678..31412
                     /locus_tag="PC512_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine(32) synthetase TtcA"
                     /protein_id="HDF2441981.1"
                     /translation="MSIQKLLSKARKAIQDFDMIQENDKIAVGLSGGKDSLTLLHILK
                     SYQRFSPQNFELIAITLNTGGVDNSPLDKLCKEINVPFYEFQTDIKEIVFDIRQEKNP
                     CALCANLRRGALNDNAKKLGCNKVALGHHKDDAIETFLMSMFYEGRVNCFSPKTYLDR
                     QDLTVIRPMVYIEEYMTKKISKDSNYPIITNPCPANGHTRREYIKNLIANLNKEMPDF
                     KRNVFGALNNSEKLFIWDKEKIKNFK"
BASE COUNT        10033 a         5626 c         3818 g        12005 t
ORIGIN      
        1 taattaaaaa tactctataa aagctaaaaa gtttttctat tcgctacatc taaaaataat
       61 tagatagagg tataaatgta tttagtttat ttatacctct agtcttttat aaattatatc
      121 tctactaaat tgatttttta gcacgaataa gtgtgctctt ggagatacca gtcatcttca
      181 caacctctct atatggctta gaatttaata accccaatgc atattgtatc tgttgattgc
      241 tgtatttctt tggcctacca tctttaaagt cctttttctt tttagcaaat tcttttccta
      301 attgagtacg ttctattatc atatttctct caagttctgc aactgcaagt aatgtagtca
      361 aaaagaattt acccattgaa gtattttcta aaaggcctat atttaaaata tgaacactta
      421 cttctttagc aaataaacct tctattagtt gtattccttc tgatgtactt ctagctagtc
      481 tatccagctt agttgcaaca agtaagtctc ccttttttag agatgatata attttttcaa
      541 atttaggcct gtttgtagta gtgcctgtat aagtttcctt tattatttta gcatcattat
      601 atttattcaa aatttcttgc tgttgctgat acaaactgtt gttgtctgtt tgattttttg
      661 tacttacacg gcaatatcca tatataataa tcatcacttc ctaacataaa gattttgtac
      721 agaagttacc cagaagcttg tttttactta tctttatcca ttttactaaa acgatttttg
      781 ggtgtcaata ctgttaactt ttgacaccat aataattcct ttataatttg tttgactatg
      841 tcaaaaatta ccaatataat gaaattaatg agtttataca aattggagga aataatatga
      901 atagtctgtt aaaagaagca atagatgaat taaaaaacat ccattgcggg gaagtttttt
      961 tattaaaaga attgttcaaa ggctatgaat ggaacaggtt ggagatgaat atcagattga
     1021 aattaggaaa actttttttg tatgaagtgg taactaatcc caatttaaat gtagaggtca
     1081 tcaataaaaa ttctgcttat cagcaaatgt ataaaaaaaa atagtgactt aaatgtatat
     1141 aatagtataa tcttcttatt gattcaaaag ttaaaacttt taatacaaaa caatcattct
     1201 attttaacat ttatcaatat gtctaaattt atataattaa cacatacgaa tagtattgtt
     1261 taaatcacat tatttaagat agataaatct taaccctact ccagcataaa tactaaaata
     1321 gggcttagaa ttatctatat ttttatccca taaaatgctt agctcttcct cttgattgaa
     1381 catatatatc tggggaaata caatagaagc gtaaatttat aaaatttcca aagtcagaaa
     1441 acttcagttc aaacttaggt ataccaaaac tttcaggtgc tatttcgtca acgccaaaat
     1501 agatgataat tccattatct gtaagataaa atgcttggtc ttcaggtata actaactcaa
     1561 cattagaata atacatttct ctattttcat ttatttgaga tttaatgtaa tcagtaatta
     1621 tattaatata atcaactcca tctctaaaaa tgtcattaag taaaagttct tttccagttg
     1681 tcaaatctat attgtaatta ttcaatgtat tgtatttagg cccatagtta ttagcaaacc
     1741 ccataaggtt taatatcata ctcagtacat aatttttatt aaaagtaact gcgtaactgg
     1801 tagataccca atagctttgt tttggaagtg aattttgaga agttgcgtta ttatattctc
     1861 gttcttcttc ctgtaagcca tttttaaaat tatttacagt cattcttaca gcattgttta
     1921 tgttatttaa aataactggg tttacatacg tggattgatt tctaatattg tatataacag
     1981 gatactttac atcatatgaa aaatacttac ttctttcaaa atcttcatta aattgtacat
     2041 ataatatatt atatgtacag gtatttgtag attgataatt ttccattaaa atcctccccc
     2101 ttttataaaa aaatcagata caatataata tgcttaaaac agtaataatg ttaatggtaa
     2161 atgtaaagaa tagaaagtat ctaaaacagc aaaaaatgac taattttgtg gtataataca
     2221 taggattgag agttatttta taggaggaaa aatatgttat tattagcaga taaatggaaa
     2281 gattatgaac ttatagatat gggaaatgga gaaaaattag aacgttgggg aagttatgta
     2341 cttagaagac cagacccaca ggttgtatgg ccaatggaat ctgaatgggc tttatggaaa
     2401 aaccctcatg gacattatca cagaagcaat aaaggtggag gtcaatggga acacaaaaaa
     2461 agatatccag aacaatggac tataaattat aaaaacttaa agtttcacat taaaccaact
     2521 ggctttaaac atactggatt attcccagag caagcagcta actgggattg gatgatagag
     2581 aaaataaaga aagctaacag acctataaaa gtgttgaatc tttttgcata tacaggtgga
     2641 gctactgtag catgtgcatc tgctggtgca gaagtatgtc atgttgatgc tgcaaaaggt
     2701 atggttaatt gggcaaaaga aaatatagaa ttatcaggtc ttaaaaatca aacagtaaga
     2761 tttatagtgg atgatgttgt aaagtttgtt gaaagagaaa taagaagagg taaaaaatat
     2821 gatgcaataa taatggaccc tccttcttat ggaagaggtc ctaaaggaga agtatggcaa
     2881 atagaagaaa agttatacag ttttgtagat ttatgtatgg gagttttatc agataaccct
     2941 ttatttttct taattaattc ttatacaaca ggattttctc caatagttct tgaaaatgta
     3001 ttgtctacaa caataggtaa aaagacaaat acaggagata tatacggtgg ggaattagga
     3061 ataccagctt ccagagatgg taagatactt ccttgtggta tatttggaag atgggagaaa
     3121 aaataatgat aaaagtcata tatgaagata accatttatt agttgtagaa aaaccagtta
     3181 acatattgtc tcaaggagat aatactaatg ataaagatat ggtaaatctt ttaaaagact
     3241 atattaaaaa aaagtataac aaacctggaa atgtatatat tggtttaata catagattgg
     3301 atagaccagt aggtggagtt atggtgtttg caaaaacatc aaaagcagca tctagattgt
     3361 ctgagcaggt aagaagtaag actttcaaaa aaacttatct agctgttgtt catggcaaga
     3421 taaaatctaa ctcagatata ctaaaagatt ttttatataa aaataaaaaa actaatatgg
     3481 taactgtagt gaaaaaaagc cataaagatg ccaaagaagc tgaacttaac tataatgtat
     3541 tagattttaa agaaaatcta agtttagttc aagttaattt aaagactggt cgttctcatc
     3601 aaataagagt tcaatttgca agcagaaaac atccattata cggagaccaa agatatggca
     3661 aagaaataaa taagattgga caacaaatat ctctttggtc caataagata gaaatttgcc
     3721 atcctactac aaaagaaaaa atggaattta catgtcatcc acctgacaaa tatccatgga
     3781 atatatttta aatctcaaat gaggtgatta tatgagtaaa aaattttcaa taggagaaat
     3841 gtctaaactt cataaaataa gcatacagac actaaggtac tatgaccaaa tagatttatt
     3901 taaacctgtt catgttgacc aagaaagcaa ttacagatat tactcaattg accaattttc
     3961 acaattagat attataaaat atttaaaata tttaggtatg cctttaaaag aaattaagtc
     4021 aaagcttgat gaaaataatg aagaaattct aaaattacta acaaataaaa ttaatatagt
     4081 ggatgaaaaa attaaagaat tagagcttat aaagaaggta ctaagcacaa agaaagaaac
     4141 tatggaaaaa ggtatgaaag tagatgaagt tggtaaaata gtgagaaaac atattccacg
     4201 aagaagtatc ttatctatag agtatgaaga aggattaagt agtgaagaaa ctatggaact
     4261 ttccagaaga caaatagcaa atatattaga agataatata tctgtgttct atggtggagt
     4321 aagtggactt gtatctatag ataaattttt aaaagaagat aaagttattt atgacaatag
     4381 ttttgttact gttgaaagag acttatttga tataaaatca caaaaacata taacagaaat
     4441 ttcatctggt gattttattt gtatgacata taaagggcct tacaaagaaa attataccgc
     4501 ttttaagaaa ctggttgatt atgttgaata taaaagaata cctattgaaa attatatata
     4561 tgaaatacct ataatagacc ctctgtctac aaacaacgaa gaggaacttc taacagaaat
     4621 tcaaatacaa gttaaaaaga gagaaattga cttaagatgt ctagtgtagt aatctagttt
     4681 acttacacat cttaatatag ttgtctatta tcaacatatg atttttctag atagtgattc
     4741 ctaacagtga gattttcaaa aaataggagg aaatatggct aatgctaatt ccctcctatt
     4801 tttaattaag ccatatcatt ttaattaagc catgtcatca cgaagtgcat caataatatt
     4861 ttcttttttt atcttattaa tagtatacaa cattgtaata aatactataa ataaaacact
     4921 aaatatacta attccaatac taaaccatgg aatcacaaaa tcaatatcat ctgtaaccat
     4981 tactttatga attagccatg aagaaattac tgctatagga agtccaaaga acaatgctct
     5041 catgccataa aaggcacact caaaattcat catcttttgg aaatcatgct cagacattcc
     5101 tacagagcga agcatggcaa gttctctacg acgtaactta atattagttg aaattgtatt
     5161 aaacacattg gcaatcgaaa tcagagaaat cataattatg aaagtataag caaaaacatt
     5221 ggcaataaaa atgtaattac ggttctcatc catcattcca tacatattgt acagattgta
     5281 ctcattcgta actccctcac tctcaataat ttgctccatt tctgcaactg actgagtagg
     5341 atttttcgat tgaaagctta aactttcaat tcctgtagaa acaccaggaa tctcaaactt
     5401 atctttggct gaataaggag ccaatactct gaagcttgct ttcttcacat ctgaacttct
     5461 gattcctgga ggagaatcag gtggcactac tttgacaaat gaaatattca cattttgtct
     5521 ctcaggtatc tccaacttgc cattagtttc aggagtgagg ctaacattca tagaagaact
     5581 gttgaaaata tcaataatat tattatcctt tgttaccata gaaacagcaa tcagttttgc
     5641 attttgtcca gtatattctt ctgctggtaa tccaagactt ttaataatat tcagataagt
     5701 tctatcatca agaaattgca tatctactgg taattcaagc atttcactca tagaatgtga
     5761 accctcatag ttcaaataat cgtctgtaag ctcacttact ttggcaacac atgaataggt
     5821 cataagtttc tgatacaaac cttcgtaaac accatttgca gtttttagct tatcgtaaag
     5881 cttcaacatt tcgttgtctt tcataccttg tgtagaaaaa ataatatcct ggtcagtaac
     5941 ctctgacctc tgatttgaca tctgttttag gtctgctact aaagcacttg tagatataaa
     6001 tagaactatg cttaaaacaa gcgacaatac aatacttcga taacgtttct tgtttctttt
     6061 aaagtttttc atagcaagaa ctccctcaag accataaact cgctgtgtta gttttgatgt
     6121 cttcacagat ttagattcaa tttttacctc atttgtctga cgaatacact ccatcactgg
     6181 tgtgttggca gcctttcttg ctggtatgta agcagaaatt aagattgtaa ccatacttac
     6241 cactgctgca acgatgattg cagggataga caatgttaat gtcaacggaa cgtttacata
     6301 gagaatattt gcaaagtttt tagctatgac agaaatcaca agtccaatac tgactatacc
     6361 gattgcaaca ccaattggta taccaatcgc accaatgcaa attccttcaa atagcaccga
     6421 atttcgtaac tgttttgctg tagctccaac agatgaaagt attccaaatt gatgtgttcg
     6481 ctcgttcaat gacatgttaa atgaattata tattagaaaa attgagccta gcatgattat
     6541 ggcaagcaca atgccaccaa ccgagtacaa aaacatattg aacaaattgt tatcagaaac
     6601 acctatgaag cgcaacacat tgtcattgaa aatggaagca tggtctttag tgctacttat
     6661 gtaagagcga atctgatgtg gatttttcaa tgtgacaaaa aggctaagac tgtcagtctt
     6721 gacttgttta tcttctttgg ttatcaaggt atatcctggt gcagaagatt cttcaaatac
     6781 gggctttcta cagataccca caactgtata agttttctta tcctgtggca caaaaacttc
     6841 actcccagca gtgtatgggt cactctgacc aagcttttca ttttcactca ttcgtttccc
     6901 tacatccaaa gaaatagtat cacctactgc aaatttgaca ccaccatctg tcgcaacttt
     6961 acttgaaaca agaatctctc tactattttc aggtaatctt ccagaaatta aagttatagg
     7021 caaagtatca aaagcttctt tgctaaatcc agcaataaaa agatatggtt tatctggatt
     7081 tctgttacct tcaagtgttg catagccaat attttcaaat gttgcagtat ttgcaacttc
     7141 atcattgact ctttgttcct gtacaaaaga agaatccaca tccaaaaact ggacatgcca
     7201 atcaccatat tttataatag ctccatttgt catatagttc atcaaagaaa ctccaaaggt
     7261 agtaactgct gtaatcatag cagctgacag aacaactcct ataattgtta caagagttcg
     7321 agtgcgattc tttttcaatc cttgcagagc aactttgtta aaaatgttca ttaacgattc
     7381 accttcctct catcacgcac tacttttcca tctgaaatac agataattct atctgcctgt
     7441 aaagcaatgt tttcatcatg tgtgacaata atgagagttt ggtgatattt actatggctc
     7501 tctttcagta actggataat ctcttgtcca tttttactgt ctaagctacc tgtaggctca
     7561 tcagcaagca taactgctgg tgcattcatc aatgcacgac caatggcaac acgttgctgt
     7621 tggccaccag aaagttgatt tggtaaatgt gtttttcgtt cttttaaacc aagcaattct
     7681 aacaagtcat ttaaccgttc ttgattgacc ttacgcttat ccataagtat aggcaatgtg
     7741 atattttcta ctacatttaa tgtgggtatc agattgtgaa actgataaat caatccaact
     7801 tgtcgcctac gaaaaatagc aagtttttca ttgctttggc catatacatc ttgcccctcc
     7861 agatatatct ttccacttgt tggtacgtct actcctgcaa tggaatgtag tagtgtagat
     7921 ttaccagaac cagaagaacc aatgattgca gtaaactctc ctttttcaat agtaagtgag
     7981 acatggtcaa gtgcagtaac cttattttca ttcttaccat aaaccttaca taaatcttca
     8041 atctttaaaa acgccattat ataagtctcc tttcatattt tataaatata tcataggact
     8101 ttcaacttac atttaagtga catttaaatg agagattcgt cactttggaa aacgaataac
     8161 aaatattgca ccaccttgtg ggtgattttg tgcagtaatt gttcctcctt gtctcataat
     8221 aatcgtctta caaagtgcca atcctattcc ataaccggct gtgcttgaat ttttcccacg
     8281 ataaaatctg ttaaatagac atggtaaatc ttctttttta aagcctgctc cgttgtcatg
     8341 aatagtaagt tgagtaaaca aaaagttgtc ctcacaaatg atatcaattt ttccattatc
     8401 acccacactc tccatgcagt ttttaaatat attttgaatt gcttctgaaa gccaatttaa
     8461 atcacccaaa atccttactc cttttggtat atcaatatgt aaagtgatat tgtgcagttc
     8521 catgggaatc aaaagttgat gaagtgcaga actaatcaaa ttattcacat caatttgttc
     8581 tttttgaaag actacaatac ctgcatctaa acgtgataat tttaaaaggg aagtaatcag
     8641 ccagtccatt cgtataagta attcctctgt ttctcgtatc aactcttttc tctcatcttc
     8701 atcagaagta ttctctaaca gtgacaaaat aagagttact gatgtaagag gagtgcgaag
     8761 ctggtgggct atgtcagcta gtgagtcagc aaggtgttct ttttcttttt tcaatgcgta
     8821 attttgctct ctaatacgta acgtcatttt agttatttca ctttgcagaa tagaaagttc
     8881 accctcatct gattcagcaa tatacagatg gttagcatta tgaagcacaa gattaatttg
     8941 ttctgaaatc tgtgcaatac ttttgtatcg atttttagta aacacaaaaa atgctattcc
     9001 aaaggtagtg gcagaaacaa tagaaagtat tccagtcata atactgattg caaatcccag
     9061 ggctacagtg agaatagtaa ttaataagaa taaaatagca aattttcgaa actctctatt
     9121 tcgaaacata acttcccccc aatctatacc ctgtcccacg aacagtcaaa attatttgtg
     9181 gacttgaagg gtcatcttct atcttctctc gcaagcgttt gatgtacaca gtcaatgtgt
     9241 tgtcattaac aaactcacct gccgcatccc acaattcatc aagtaatctt accctcgtaa
     9301 taatactttt aggattgcta ataaacacca ataacaaacg gtattctaaa gctgaaagaa
     9361 aaacctcatt gccattcttt ttcacaacac cggttgccgt atctacataa agcccacaaa
     9421 tttcaaaagt tgacccaaaa cgcccacttt ttcgtagtgc tgttctaatt cgcgcaatca
     9481 gttcacgtgg acgaaaaggt ttagtaatat aatcatctgc acccatattc agtccagtaa
     9541 caacacttga ttcatcaccg gaagctgtca aaaagataac aggaatgtct tgcttttctt
     9601 tgatttctgt gcaaatcgta aacccatttc catcaggtaa agaaatatca ataagtgcca
     9661 aatcaaattt attcttagca atctctacaa gtgcttcact tcttgtggat acatgggtta
     9721 ctataaatcc ttctgaatta agcaaaagaa taagattttt ggcaattgct ttatcatcct
     9781 caactaaaaa tatccgtttc atttactttc atcctccttt attttattag ttttatatat
     9841 tccagcagag caatagtaca ctactatttt acttatcatt acacaatttt cagtagtttc
     9901 ttttgttctt atataatcca tgcataatac ctccattgat ttattatatt tcttataaca
     9961 taaatacaca agataagaca aaaaacataa tgtaagtgca agttttttaa ctcactaact
    10021 tataaacata cactcctact aacactactt tcttgatgac acatcttaca agcttatatt
    10081 catacatcaa tgaaaaatta aatttatcca tttattaaaa taaaaggcaa tagcttctat
    10141 agctaatgcc ctttatctta aaatgattta aatactatac aatttttata aatggctata
    10201 aataaactcg tatagaatat aaaatttatc tacagtcttt tgttatacaa aatttataac
    10261 ctcttataga acaaatttac cactttgcaa acttatcact tttactcagc tatattataa
    10321 acttttaatt tatctttgtt taaatgtttc ttcttaactt ctactaaagc ttttagcgta
    10381 tccaaagatg tcattatttc agtagaaaat tcaatggctg ttcttctcat cttaaatcca
    10441 tctcttgtag agtcatttcc tttagttggt gtatttatta ctatatcaac ttgtttattt
    10501 cttatagcat ctaatatgtt tggtctaggc tcttcaattc tatttactat atcagcctct
    10561 attccatttt ctcttaaact cttcgctgtt ccttctgtag caacaaaagt atatcctaat
    10621 tctttcatat cttttgctat ctctataaac tcatctttat catgattatt tacagtagca
    10681 agtactactc ctctttcatc agacatatgt ctacctgctg ccaagaaccc tttatataag
    10741 gcttcttcta aattttctcc tacacctaga acttctcctg tagacttcat ttcaggtcct
    10801 agacttactt caactttaga taatttagac attgagaata ctggtacttt tactgatact
    10861 aattttggct ctttgtaaac tcctgtacta tatcctaaat cctttaattt agctcctaac
    10921 atacacttag tagccaagtc aactattggt actccactta ctttacttat atatggaact
    10981 gttctactag ctctagggtt aacctcaatt atatataatt cattttgaaa ttctataaat
    11041 tgtatattaa ccataccaag cacattaagg tctaaagcta tttttttagt gtattctact
    11101 attttttctt ttatttcatc agatatattt tgacttggat acattgttgt actatctcca
    11161 gagtgaactc cagctctttc taaatgctcc attataccag gtatcaatat atcttcttta
    11221 tcacatatag catctacttc tatttctcta ccagttagat atttatctat aagtactgga
    11281 tttttatggt ctctatcaaa tgcatcatcc aaatactgaa ttagtttttc ttcgttataa
    11341 gttatttcca taccttgacc accaagtaca taagatggtc taactaatac tggataacct
    11401 aactccttag caatttcaac accttcatta gttgtccata caccttttcc ttttggtcta
    11461 tttatatcta gtctctctag taaatcatca aatttttctc tatcttctgc tgcatctata
    11521 tctctaaagt ctgttcccag tataggtata tttttttcat gtaaaaactt agccaatttt
    11581 atagctgttt gtccaccaaa ctgtagtatt acaccttctg gtttttcttt ttctattata
    11641 tttaaaactt cttcttctgt taatggttca aaatacaact tatcagatgt atcaaaatcc
    11701 gtacttacag tttcagggtt attgtttaca attatagttt ctattcccat ttttcttaaa
    11761 gattttacac agtgaactga acaatagtca aattctattc cttgacctat tcttattgga
    11821 ccagaaccca atactacaac ttttctctta tcactaacta ctacctcatc atattgttca
    11881 taagttgaat agtaataagg tgatagagct tcaaattctc ctccacatgt atcaaccatt
    11941 ttataaactg gttgtatatt atataaactt ctcaattcat ataatttttc tgggcttatc
    12001 ttcattaagt cagatatacc tttatcagaa aatccctttt tctttaattc atgtaaatat
    12061 tctttatcta agtcttctat ttttagaact tttaactttt cttcttgttc tactatccat
    12121 ttaaatttat ttataaacca cttatcaaca ccagttattt ctgatatcat ttctacttta
    12181 tagcctcttc ttatcatttc agctaagtca aatagtctct catcatcagg tactactact
    12241 ctagccttta attcttctaa tgttctacct tctgatggag catgaaccaa tgaatatttt
    12301 cctgtttcaa gtgatcttat acctttaaga atagcagcct caaagttact tcctatactc
    12361 atgatttcac cagttgccat catcttagtt cctaattttc tattggcatg tctaaattta
    12421 tcaaatggcc actttggtat ttttactacc acataatcta atgttggctc aaaacaagca
    12481 taagtttttt tagttactgc attttctatc tcatccaaag tataacctaa agctatctta
    12541 gctgctactt ttgctattgg gtatcctgta gcttttgatg ctagggctga tgacctacta
    12601 actcttggat ttatttctat tatcgcatat tctaaactat gtgggtttaa agctatttga
    12661 acgttacatc caccttgaac ctctattgca tttattatgt ctattgatgc ctttctaagt
    12721 agttgatact cttcatcact tagagtttga cttggagcaa caactatact gtctcccgta
    12781 tgaactccaa ctgggtctac attttccata ttacatacag ttatacagtt tccatttcca
    12841 tccctcatta cttcgtattc tatttctttc caacctttta tactcttttc aagaagaact
    12901 tgtccaacag gacttagctg tagtccatgt gaaagtattt ctcttaattc ttcctcagta
    12961 tcagctatac ctccaccagt tccacctagc gtatatgctg gtcttacaac tactggatat
    13021 cctatcttat tggcaaactc aagacctgct tctaaatttg taactatatc actaactatt
    13081 actggttgat ttatttcttt cattacttct ctaaataaat ctctatcttc gccctttttt
    13141 atagattcta tagatgttcc tataactttt acattatatt tatctaatat accagcatca
    13201 tgtaattcta cagctaagtt taatcctgtc tgaccaccca tacctgcaag taaactatct
    13261 ggtttttctt tttctattat tttttctata aattctattg ttaatggttc tatatatatt
    13321 ttatctgcaa tttctttatc agtcattata gtagctgggt tactatttac taatacaact
    13381 tcaattccct cttcttttaa tgcttggcag gcctgtgttc ctgaatagtc aaactctgca
    13441 gcttgaccta ttattattgg ccctgaccct aatactaaag ttttctttat actatctaat
    13501 ttaggcataa ctctttctcc ttatctaaac aattttcaca gttcttatct tcatcatcta
    13561 tacaatcaac tttaattact ttattttatc ttaaattcaa atttactcat caatacatct
    13621 atttaataca tctatgttaa ttaaaccaaa ctttttgatt taagttattc ttgtttttta
    13681 gttagctatt ctaatgttat ttattttact aattctaaaa atttatcaaa aatatagtca
    13741 ttatcttttg gtcctgggca agcttcagga tggtattgaa cactgtatac atctagtttc
    13801 tcatgtctca ttccttcaac agtattatca tttaaattta tatgtgtcac tttcatttgt
    13861 tcaggaactt ctgaaacata ataaccatga ttttgagaag ttataaatac ttttccttct
    13921 tctaaatctt taactggatg atttccacct ctatgcccaa atttaagttt agcagttttt
    13981 cctccaagag ctaaagctaa aagttgatgt cctaagcata ttccaactat aggtttttta
    14041 ccaataagag cttttatatt ttctataaca tcttctaggt cttctgggtc tccaggtcca
    14101 tttgacaaga atattaagtc agggtttata ctcaatacat cttctggaga tgttgtagct
    14161 ggaaatattg ttatatcaca tccacgagct ataaatgatc ttaatatatt tctttttact
    14221 ccaaaatcca taacagccac ttttggacca tttcccttta tatgctctac ttcttttctt
    14281 gtaacagttc taactgcttc tgtatttgaa aacttatcca atttatgttt aacatcttct
    14341 aatttactgt cttctaatgt aattatacct ttcatggttc cattatttct aagtatctta
    14401 gtcaaagctc ttgtatctat tccttcaagt ccgataactt tattttgctt taaatattgg
    14461 tctatatcaa tttcacatct aaaattactt ggagaatcac ttttctccct tactatgaat
    14521 ccctttactt gaactttttc agactctgct gatgataaat ttataccata atttcctaca
    14581 agaggataag tcatagtaac tatttgacca tagtaagaag ggtctgttaa aacttcacca
    14641 tatcctatca ttgaagtatt aaatactact tctcctacac tttcttctaa atatccaaat
    14701 gcctttccta taaaaactgt tccatcttct aatattaacc ttgctttcat actacagtac
    14761 ctcctataat tctctttaga caaactaaag aacattaact aaatataagc ttttaaatat
    14821 ctatatctat ttttcacttt tacattctag ttttatactt atttacattt attttttatc
    14881 tttttctatt atactacaaa tttcttaaaa aaaagaagtt atctcaaaag taaaaactcc
    14941 tagaaaaaat aacctctttt ttttatttaa taattaaatt cttaaactat acaatcaact
    15001 taatttctat tcagctatat tgtaaacttt taactcatct ttatttaaat gtttcttctt
    15061 aacttctact aaagctttta gtgtatccaa agatgtcatt atttcagtag aaaattcaat
    15121 agctgttctt cttatcttaa atccatctct tgtagagtca tttcctttag ttggtgtatt
    15181 tattactata tcaacttgtt tatttcttat agcatctaat atgtttggtc tagattcttc
    15241 tactctattt actatatcag cctctattcc attttctctt aagctattag ctgttccttc
    15301 tgtagcaaca aaagtatatc ctaattcttt catatctttt gctatctcta taaactcatc
    15361 tttatcatga ttatttacag tagcaagtac tactcctctt tcatcagaca tatgtctacc
    15421 tgctgccaag aaccctttat ataaggcttc ttctaaattt tctcctacac ctaggacttc
    15481 tcctgtagac ttcatttcag gtcctagact tacttcaact ttagataatt tagacattga
    15541 gaatactggt acttttactg atactaattt tggctctttg taaactcctg taccatatcc
    15601 taaatccttt aatttagctc ctaacataca cttagtagcc aagtcaacta ttggtactcc
    15661 acttacttta cttatatacg gaactgttct actagctcta gggttaacct caattatata
    15721 taattcattt tgaaattcta taaactgtat attaaccata ccaagcacat taaggtctaa
    15781 agctattttt ttagtgtatt ctactatctt ttcttttatt tcatcagata tattttgact
    15841 tggatacatt gttgtactat ctccagagtg aactccagct ctttctaaat gttccattat
    15901 accaggtatc aatatatctt ccttatcaca tatagcatct acttctattt ctctaccagt
    15961 tagatattta tctataagta ctggattttt atggtctcta tcaaatgcat cttgtaggta
    16021 ttgagataat ttttcttcgt tataagttat ttccatacct tgaccaccaa gtacataaga
    16081 tggtctaact aatactggat aacctaactc attagcaact tcaatacctt cgttaagtga
    16141 ccatacaccc tttccttttg gtctatttat atctagtctc tctagtaaat catcaaattt
    16201 ttctctatct tctgctgcat ctatatcatc aaaatcagtt cccagtatag gtatattttt
    16261 ttcatgtaaa aatttagcca attttatagc tgtttgtcca ccaaactgta gtattacacc
    16321 ttctggtttt tctttttcta ttatacttaa aacttcttct tctgttaatg gttcaaaata
    16381 cagcttatct gatgtatcaa agtctgtact tacagtttca gggttattgt ttatgattat
    16441 agtttctatg tccatttttc ttaaagattt tacacagtga actgaacaat agtcaaattc
    16501 tataccttga cctattctta ttggaccaga acctaatact atcacctttt tcttatcact
    16561 aacaactacc tcatcatatt gctcataagt tgaataatag taaggagata tagcatctat
    16621 ctcacctgca caagtatcaa ccattttata tgctggtttg atattgtata gacttctcaa
    16681 ttcatataat ttttctggac ttatcttcat taggtcagat atacctttat cagagaatcc
    16741 ctttttcttt aattcaagaa gatagtcttt agttaaatct tcaattttca taacttttaa
    16801 tttttcttct tgctctacta tccatttaaa tttatttata aaccatttat ctatacctgt
    16861 aatttgttct atcatttcta ctttatagcc tcttcttatc atttcagcta aatcaaatag
    16921 tctctcatca tcaggtacta caactctttt ctttaattcc tcaatgcttc tctcctcaga
    16981 tggtgtgtga actaatgaat attttcctgt ttcaagtgat cttatccctt taagaatagc
    17041 agcctcaaaa ttacttccta tactcataat ttcaccagtt gccatcatct tagttcctaa
    17101 ttttctattt gcttttttaa atttatcaaa aggccatttt ggtatttttg ccaccacata
    17161 atctatagtt ggttcaaaac aagcataagt ttttttagtt actgcatttt ctatctcatc
    17221 taaagtataa cctaaagcta tttttgatga aactttagct attggatatc ctgtagcttt
    17281 tgatgctaaa gctgatgacc tactaactct tggatttatc tctataactg catattcaaa
    17341 actatgtgga ttaagtgcaa attgaacgtt acaaccacct tgaacttcta ctgcatttaa
    17401 tatatctaaa gatgcttttt taagcattgc acattctttg ttacttaaag tttgagttgg
    17461 agcaacaact atactgtctc ctgtatgaac tccgactggg tctatatttt ccatgttaca
    17521 tacaactata caatttccct ttgaatctct tattacctca tattctattt ctttccaacc
    17581 ttttatactc ttttcaatta atacttgtcc aacaggactt aattgtagac catgtgaaag
    17641 tatttctctt aattcttcct cattatcagc tataccccca ccagttccac ctagtgtgta
    17701 tgctggtctt acaactactg gataaccaat tgtaagtgca taatcaagac ctgcttgtaa
    17761 atctgtaact atatcactaa ctattacagg ctgatttatt tctttcatta cttctctaaa
    17821 tatatctcta tcttcacctt ttttgataga ttctactgaa gtacctatta tttttactcc
    17881 atatttatct agtatgcctt tttcataaag ttcaactgct aggtttagcc ctgtttgtcc
    17941 acccatacct gcaagtaaac tgtctggtct ttctttttct attatttttt ctataaattc
    18001 tattgttaat ggttctatat atattttatc tgccacttct ttatcagtca ttatagtggc
    18061 tggattacta tttattaata caacttcaat cccttcctct ttcaaagact ggcaagcttg
    18121 tgttcctgaa tagtcaaact ctgcagcttg acctattatt attggtcctg accctaatac
    18181 taaagttttc tttatactat ctaatttagg cataaatttt tctccttatc taaatggttt
    18241 ttactatctg taaataatac taaatctata ttaatgctaa gaatttatta aatatacaat
    18301 ctaaatcttc ttttgttgtg tattctggaa tgtactgaac actatatatt ggtaattcct
    18361 tatgtctcat tccttctata gtattgtcat ttaaatttat gtgagttact tctgtatttt
    18421 ctggcatttc tgaaacatta tatccatgat tttgagaagt tataaatacc tttccagttt
    18481 ctaaacattt aactgggtga ttacctcctc tatgtccaaa tacaagcttt gaagtctttc
    18541 ctcctaatgc caatgctaaa atttgatgtc ctaaacctat tcctgtcaat ggctttttgc
    18601 ctattaattt ttttatattt tcaactatat catttatatc ctctggattt cctgggccat
    18661 tagataataa gattaagtca ggatttatat ttaaaatttc ttctactgta gtcattgctg
    18721 gtactatagt tatatcacag ttacaagcct taagagactc tagtacacta tttttaacac
    18781 caaagtctat aactacaact ttagctccag taccttttat attttcaatt tcttttcttg
    18841 taacattttt tactgaatct ttgttacaat gctcttctaa tttagactga acatcttgta
    18901 atgatacatt ttctaaagtt ataattcctc tcttagttcc attgtttcta ataattttag
    18961 ttaatgctct tgtatctatt ccttcaagtc ctattacctt attttgcttt agatatgtgt
    19021 ctatatccat ttcacatcta aaattatttg ggttatcact tttttctctt acaataagtc
    19081 cttttacttg caccttattt gattcaacat cttctaaatt tattccatag tttcctataa
    19141 gtggataagt catagtaact atttgtccat aataagttgc atctgtcaat agttctccat
    19201 acccagccat tgaagtatta aatacaactt ctccaatagc ttcctttaga tatccaaatg
    19261 cttttccttc aaatactgtt ccatcttcta aaattaattt ccccttcatg taagctacct
    19321 cccaaatatt ttatctaagc attttctatt tctcttacaa tattaatagc tgattctctt
    19381 ggattttctg cttttgttat aggtcttcca acaactaaat aatgagcacc tttttttatt
    19441 gcatctgatg gagttacaac tcttttttgg tctccaacct ctgctgattt aggtcttatt
    19501 cctgggcaaa ctgttataaa atcagttcca catgcttcta ctattttatc tacttcttgc
    19561 gctgaacaaa caaccccatc tattcctgat tcttttgcca gtttagctct ctttatagct
    19621 aactcttctg ttgtcatatt acatcctatg tcctgtaaat cttggttgct taatgaagtt
    19681 aaaactgtta ctccaactac taatggcttt tctatattta atctttctgc ttcttcccta
    19741 gcaattagtg cacattgtct cattccttcc atatctgata catgtattgt cattaaccaa
    19801 acattatctc tcactgcagc tttcactgca cttttcatag tatttggtat atcatggaat
    19861 ttaaggtcta aaaatatttt tttacctttt tctttaagat aatctattgt tttacctttt
    19921 gtggcaacgt attgctctag ccctacctta aatatgtcta cactatcttc taatctgtct
    19981 attagttctt tagctttatc aaattcgtca gtatcaattg caactatcaa tttttcttta
    20041 ccatttatca tttttacatc tcctttttaa taaagcctaa ataatcataa aaaaatcctc
    20101 acaccaaaag aggcataagg attttatcta tacataactc tattcattag ctatgagata
    20161 tctttcccag tctctctgga ctagtttaaa agactttatt atatttaaat ttttatttta
    20221 tactcatcaa aaacctctag aagatttact agaggttata tactaacatt atctataacc
    20281 ctttagtctc tctggactac tttaaggaat ttagctgtaa tatttttctt tatttatata
    20341 actttatgta tctataggat aatttaaagt tttatctttt ttataattaa accactaatt
    20401 gctttttatg tcaataagtc tttgaattat tcttcatctt tatcaaacaa ttttttctca
    20461 aaatatgatt ctgcattata tattgcagca actggattat gcccagttac tctatctttg
    20521 acaactaaag ttgttatagg agcttccata tatttcatgg ctaaagtatc gtgaccaaca
    20581 cataatccaa gaattacatt aaggtcaacc ttagcttcat ttaaaaataa agcttgtcct
    20641 attggattgc acattacctc atctgaacac tttgatattg tttgagatgc ttctagtcca
    20701 attgtactct taggcattgc cccattttta catataacag aaaatacttc aaacccatga
    20761 tgttcaaata ttttttgcac tgtttgcatt tctcttttta gtccaataca aaatgctatg
    20821 ccaatctttt tataaccaca ctttttagca aactctataa tctcttttag tctagtatat
    20881 tgacaatacc cctctgcttc aactaatcca gcattataag ctatttttct attctcttct
    20941 tcttcataaa gttgctttgc tttttgttgt agttcaattt ctctagttgg acatatcttc
    21001 attaatttat ccatatttcc attagaacag cctctaagat tacattttcc acacttatac
    21061 atatccaata tccccttcca aaattttatt catcttgcga ttcttctttt tctagagtta
    21121 cattttcttc ttgggtttct tcttctggtt tcacatgctc gactacagtt ataaaatatg
    21181 attttcctat tttattcctt ataggaagtt tttcatatga aacatctatt ttatttttta
    21241 tacaagctat atcaaaatgt cttaaggcta cacctaagct aaccttattc atatcttcac
    21301 agtgtttctt aggtctcttt tcaaataaat gaagacctcg ttcatcctta tggaaatacc
    21361 acggttgaga attttttaca gatggagctc ttcttgtcaa ttctaagata tctttccact
    21421 ttctattcct atttatctta tttatcatat cttttactgg ctttctatca ggtctagcat
    21481 atctcgtcct aaacaactct tcattttttg ctggatatcc aaatgctatt attatataag
    21541 gattttctat tttgttttca tcatcttctt ctgtttttat tccagctaga taatctaaat
    21601 catcttcctc atcttcttca aaattcttat tcccaatatc tacaaattcc aagatatctt
    21661 ctctctttaa gtttccttcc aaccagcaag tagctattcc caatgttgta aggcgcaaaa
    21721 ctacaccttc tgtagcaaat cctatattct gtaaatagtc ctcacctttg tctgatgtaa
    21781 ctactatata atgaggtgcc tttactttac attccttacc catcaaaaaa tgtattatat
    21841 gacctctatc aacaacatgt gctttaatat ttaaatcttc atttaagtat tctaaatttt
    21901 tacaacttct ttttatttct tccatcaatg gcttttttat cttcttactg gaaaaatttc
    21961 ttacagattt tctataaaaa atggcttcat aaagctccat ttatgccctc ctaactgaaa
    22021 tcttctgacg tataaactct ataaatttat ataaatactt tatatttttt atagttttat
    22081 ttcctttttc ctcctgccct attttgaaat tcataagaat atctactcta gtttaatata
    22141 gcattcaaaa ggcttaaatt ctaccttatc aatgtctata cattagcata atttttttat
    22201 ttgattttct atgctaattt aaataacaac actagctatt acctttttaa ttaagctttg
    22261 ccagaaaaat tttttttcat ttataaatat ctatctcatt attatattat aagttttttt
    22321 cggtattctt gtatagcttt tcactaaaaa agtattttta tttctacttt aatattatta
    22381 tcaacaaaaa acatactgct taaataagtt tgttatcctc ataatttgtt ttaattaaaa
    22441 tatttttttt atttctcaat ctataaagta taaatatttt gaatatgacc caaaatctaa
    22501 gtaaagttat aatattttat aagttgttca atattaaaaa cataagtaat gttataatac
    22561 tttataagtt attcaatatt aaaaatatag gaggataaat atgaatttaa atagaaattt
    22621 agaaaaatac gctgaattag caataaaagt tggagttaac atacagccag gtcaaattct
    22681 acttataaag tcaccaatag aatgtgctga ttttgcaaga aatgcactta aagaagcata
    22741 taaatgtggt gctaaaaatg tttatataga gtggtctgat gaagaaagta ctcttattaa
    22801 atacttatat gctccagatg aagcatttca tgagttcccc aaatggacag cagaacaata
    22861 tgtagatata gcaaaagaag gtggggcatt tttatcagtc tatgcccaaa atccagattt
    22921 attaaaagat gttgaccctg aaagagttgc aaattttcag aaggcatctg gaaaagcttt
    22981 aaaagaatgg cgttcttaca ctctaactga taaatgtaaa tggaatatag tctctgtgcc
    23041 aacaaaagat tgggcaaaaa aagtgtttcc aaatttatca gaagataaag caatagaaaa
    23101 actgtgggat gctatattta aatgttcaag agtagatggt caggacccta taaaagcatg
    23161 ggaagaacat aatgaaaatc ttaaatctaa aatggacttt ctaaataaaa ataactttaa
    23221 aactttaaaa tataaatcct caaaaactga tttgactcta gacttgccaa agggtcatgt
    23281 ttggctaagt ggagcatcca aagaccctaa tggaataagt tttaatccga atattccaac
    23341 tgaagagatt tttggaatgc cacataagtt taaagtaaat ggaactgttt atagtacaaa
    23401 acctcttgtt tatggtggaa acataattga caatttcttc ttaacattta aagatggtaa
    23461 aataatagat ttctctgctg aaaagggact agatacacta gaaaaactta ttgaaacgga
    23521 tgaaggctct cattatttag gagaagtcgc tcttgttcca tacaactcac caatatccaa
    23581 tacggatata attttttata atactctata tgatgaaaat gcttcttgcc actttgcaat
    23641 tggttctgct tataagactt gtctggaagg tggaaataat ttaaaagatg aagaattgga
    23701 tgaacatggt gtaaatgaca gtttaacaca tgtagatttt atgattggtt ctgctgatat
    23761 ggatattatt ggtgagactt atgatggaaa gcaaatacag atttttaaaa atggtaattg
    23821 ggctttttaa catatgattt taactaaaaa gggctgatgg aagttatacc agacttccca
    23881 gcccttttta atgttgatga taaatatttt ttatattaat taatctcatt attatagatt
    23941 aattcctatt gttttaaaca taagtatcta aaacttatat ttatattata tataaaatat
    24001 cctatttagt aaaaccttta ttttaattta tatgctaaaa atttaacttt gctatttcaa
    24061 cagcagactt tgcatccttt gaataataat cagcacccat ttcttcagcg tattcttctg
    24121 tcaaaactgc acctcctaca aatacctttg catttatctc attatctctc agtgcctgaa
    24181 ttgtatcttt catactttga acagtcgtag tcataagtgc acttaatcct actaatttta
    24241 tatttctctt tttagcaact tccactactt cttcaatagg gacatcttta cctaaatcta
    24301 taacttcata tccataattt tctagcatta tttttactat atttttccca atatcatgga
    24361 tatcaccttt tactgtagca actattattt ttcctttgga tacattattg ctacttttac
    24421 ttaataaagt ttcctttatt gtatttaatg aaacttttac cgtttctgct gattgaatca
    24481 attgtggtaa aaatatatct ccactatcat atctttttcc tactttatca agagcaggaa
    24541 ttaaaatctc atctaatata taattttcat ccttctcttt taaaagattc agtgttacat
    24601 tttttgcttc atcttttaat cctctttcaa ctaaaatatc caagggcaaa tctttatcaa
    24661 tctttgtaga tgaatccgat ttttttgaat tatttatatt gctatattga tttatatagt
    24721 ttatacatcc tttatctgtg ttatttaata ttttaaaaga attgatagct tccatcatac
    24781 tatattcatt tggatttata attgctaaat caagccctgc ccctaaagct aatgttagaa
    24841 aagaagcatt aagtgctttc ctatttggaa gaccaaatga aatatttgaa acacctaata
    24901 tagtttttac tcctagtgtc tttaccattg ttatagcttt tatagtttct attgcttctt
    24961 cttgttgtgc tgaaacagtt aatgataaac agtctataaa tatatctttt ggttttatcc
    25021 cataagaaac tgctctatta actatccttt ttgctatttc aaatctttct tcagcctttt
    25081 taggtatccc cttttcatca agtgtaagtc caaccacaca tgaaccatac tttttaacta
    25141 ttggtaatat actttctaaa gactcctctt tgccatttac agagtttact attgttctac
    25201 cattataata tctaagtcct tgctctaagg cctctacatt ggaagaatca acttgtaaag
    25261 gtgtatctac tactgcttga atctctctta ttaattttgg cattagtttt ttttcatcaa
    25321 tctctggaag accaacattt actccaagta tttgtgctcc agcatttact tgctctaaac
    25381 ctaaatttat agcataatca acattttcat tttttaatgc ttcttgtaga gattttctac
    25441 ctgtgggatt caatctttct ccaacaactg taggcgattg tacttccaca aattttgatg
    25501 gtgaacagac tacacattta tcaattttct cgatacatcc ctttgtaaca gaatttatat
    25561 tctcagatat ttcttttata aaacttggat tcgtaccaca acatccacct attatagtag
    25621 caccaacttc aacgaacttt ttaacccctt caaaaaattc ttttgcatcg acatcatata
    25681 tagcctctcc atcaactata tttggaagac ctgcatttgc ttgaaccata acagggactg
    25741 tagctcttga tgctattttt tcaactattg gtaaaagttg tttaggtcct aatgaacaat
    25801 taactcctat tgcatctaca cctagacctt ctatagtagc caccatacat tctggcatac
    25861 atccagtaaa acttcttcca ccttcatcaa atgtcatagt acagaaaata ggtaaatcag
    25921 agttttcttt tgctgctaat acagctactt tagcttcata taaatccatc atagtctcta
    25981 ttactattac atcaactcca gatttaacgc cttgtagtac ttgtctttta aatatttcat
    26041 atgctttatc aaaacttaaa gtacccatag gctctagcat ttctcctata ggaccaatat
    26101 ctaaagctac atatcttggt ttagtattat ctacattttc tatagctttt ctagccacca
    26161 aaacagcatt gtcaatcact tcttctacag tatacttact atctaatttt agttcattac
    26221 atccaaaagt atttgtaaga attacattcg aacctgcctc taagtatgct gtatgtattt
    26281 ctataagttt atctggattt tgaagaccaa atacttctgg attttcacct aactttaacc
    26341 ctttttgttg aagcattgtt cccattgcac catcaaatat taatatatta tttttcagat
    26401 attgtcttat ttccacaaga gttcgctccc tttctatatg tacagtttct atagttttta
    26461 caattttcac acgacttttc tttcttagat ttatttattc ttgtattaga aatacctata
    26521 atagccacta ctgactttct cggtatcata attccattag aagtaattgt tagacctatt
    26581 tgtttttgag cattcaaaac gtttaatata tctatatttt tttctattgg taaatctcca
    26641 tatcctgggc tatatcgcat agttataaat ttatcttgct ttaaaaaaac cttttctaaa
    26701 ttattttgaa caatgtcaca cacttcttct attgctgttg ttccacatga atcaattatt
    26761 agtccttttg ttaaatttga ataagagtgt cgtcttattt ctttttctat atctatccct
    26821 atagtagctg ccataattac acactcatta cattctttta aaagttcata tacatattta
    26881 ctctctaatg ttaaatttgt tccctctaat tctacaacat tatctttatt tattctaata
    26941 ggataaatcc tagataaata tctaggattt attttatttt tagttatagc tacacattca
    27001 tcaatagtat atttaaggtc tttatctatc tcttgacctc tgtattgtaa atatcttaaa
    27061 acttcacttt gatttatgct tatatcttct cttccaatta aattattctc catatatatt
    27121 taaagaaaat cctttatcta aaacatcttt tgcatattcc tttgccccaa ataaagataa
    27181 gtctctgtag tttccacatt ctatagctgt agctgctggc attttatctg attcaagaac
    27241 tttttttaat gcttcttcta aaccaatctt aactgttttg gcatctacat ctccccatag
    27301 tattaaataa aatcctgttc tacatcccat tggagataag tctattacac catctaatgt
    27361 atctcttaaa taagtagcta aaagatgctc taaaccgtgc atagcagcag ttccaaaact
    27421 ttctacattt ggctgtaaaa atctcaagtc aaatttagtt actttatctc cctttactcc
    27481 atcaagtaca ctacactttc ttacaaaagg agcttttact tttgtatggt ctagcttaaa
    27541 actttctact ttttccatta tttaatcctc cattatactt taaaatttgt tacattaatt
    27601 ctaaaaaaaa ctcttcctat ctattattga taagaagagt atattatttc aagtcatctc
    27661 atcgttgtta gcaggaccac ctgataaaag gttggtatag gatcactgag ctaactctct
    27721 cccctaactc ttgataagta tcttattaaa ctgacttaaa ttatatatta cttttttatt
    27781 tttgtaaaca ctttattgtt ataatattta tatcacataa tcgtactttt attttataac
    27841 taagctgatt gtattattgg cagttgtact tcaaacacag tttgatattt atcgcttgaa
    27901 acagtaattt ctccatcatg taaatttaca atattttttg taatcgcaag acccaatcca
    27961 gaacctccaa catttctatt tctcgatttt tcaactctat aaaatctatc aaatatattt
    28021 ggtaaatcta acactggaat tggttcccca taatttatca cttttacaac cgccatatct
    28081 tcctttttct ctgtgactat atctacataa tgcccatctt ttccatattt cacagcatta
    28141 gttataagat tttcaaatgc tcttaccaat ttatttggat cagcttttac aattaatttt
    28201 tcttcattaa aattaattct actaaccata aattcttgtt taaaataaat ttcaaattga
    28261 gatactactt gacttaataa ctctactaaa tttatttcta ttttgtttaa ttttattgta
    28321 ttattttgca ttttagtcaa ttcaaacaaa tcatttataa gaacatttaa atttttcgat
    28381 ttttcatatg caatatcaac atagtacatc atctgaactt catctttata cttaccttct
    28441 tctatcactc ctaaataacc cattatggat gtcaaaggtg ttcttaagtc atgtgacaca
    28501 tttgttatta aatctgtttt tgtctgctga gcttgtctct cttcaatagt tatatttcta
    28561 agttgatgga ctatattatt gattttatgt gctagttcat caatatcatc cttttcttta
    28621 tcctttaata tatctaaatc atactcaata tctatacttt tttctaagtt accttcatcc
    28681 attaaattta cagcactttt aatgatttct aatttttgat tttttctatt agtctttctt
    28741 ataaaatcta caatttgctt atttctcttg tacgatataa tggaataaat tgctaatgat
    28801 gtgattgtaa ataaaaatgg ataaaataaa tcatacccta taagacttct gaaatctctt
    28861 gcttgatata caagttgatt aactacagac atatcactat tgacatataa tgattttatt
    28921 atatacatac ttgttaaaat aagcattgaa gttaaagcac agcttattat aagatctaat
    28981 atgggtcgaa acatatgatt taataaactt ttatttttca attttatatc ctactcccca
    29041 tacagtatga attatttttt ctccatctgt atatttttca attttatccc ttattctgct
    29101 catatgaacc attacagtat tattagattg gtaatatttc tctttccata ccttttcaaa
    29161 tatttcttct gtactatata ctctgccttt attatttgct agtaaatata atatatcaaa
    29221 ttctcttgat gtcaaaatta tttcatttcc agccactgtt acactatgtt tttccttatc
    29281 tataattact actccaacct ttatgacatc tttatcttca ttattagcac cactaaaata
    29341 atatgctctt ctaatcagcg acttcactct cacagtaagt tcaagtgggt taaatggttt
    29401 tgtcaaatag tcatctgcac cagtcattat cccttgtatt ttatccatgt cttctgattt
    29461 tgcacttaac ataagtattg gtatattcaa actttctcta acttttctac aaacttctat
    29521 cccatccatt ttaggcatca ttatatccaa tatcattaaa tgaatatttt ccttttttaa
    29581 aatatctaga gcctcttttc catcttcagc tttaattaca ttatatccac tatttaaaag
    29641 atatatctct ataaggtctc ttatttcctt ttcatcatcc acaacaagaa ctgtattatt
    29701 catttttaca catcctaact taatctttgt atatagcttt attcatataa aattatacta
    29761 tattttagtt agtgtaatct ataaatttat taatttctaa atttccaata taatacaaat
    29821 tatttacaca tttatattat ttattttgta aatattcttc taaagttaat ccttttgaat
    29881 aaatttcctc agcagcatcc ttaccaacat atctaatatg ccatggttca tatgctgtac
    29941 ctgttatatc ttctttacct tcaggatatc ttattataaa tccaaacttg tgagcatttt
    30001 ctgccaacca tttagcttct tttgtacttc caacaaacca tctttctgga tttgttaaat
    30061 caatacaaag tccagtttgg tgctcactgt aaccaggctt tgctacatat gcatctgcct
    30121 tttctcgccc ctgagatttt acccttcttg tataagtatc cagttgagta tcataagatc
    30181 tgtatgctga agaccctaaa aactgtattc cttctgaatt agcttgctta actaaatctt
    30241 caactgcctt tgcaggttct cctgccattt gtttttcttc ctctgttgct tcttcaacaa
    30301 aaggtatgtt taccttagta atattttcag gagtatagtt tttgctaatt ccatttgtct
    30361 tgtttaccaa taatatattt gatatactat ttgagtgatt tttattttga gaatttgcct
    30421 caacatcttg ttctgaatca tgttgagcag ctactattgg atctttatct ttcttaagta
    30481 atctatcttt agatataaat acacttataa atactactaa aataatggct cctattaatt
    30541 taaatttttt cataattaaa tcttctcctt tttgttatgt ttgctataat gttaatttta
    30601 gagtataaga cttaagtatt ttataagtaa atcttaaata aatcttaaat ttaatatttt
    30661 taaaggatgg tgataaaatg tctatacaaa aacttctaag taaagctcgt aaggctatac
    30721 aagattttga tatgatacaa gaaaatgata aaattgcggt tggactttct ggtggaaaag
    30781 atagtttaac tctacttcat atacttaaaa gttatcaaag attttctcca caaaactttg
    30841 aattgatagc cataacatta aatactggag gtgttgataa ttctccacta gataaattgt
    30901 gtaaagaaat aaatgttcct ttttatgaat ttcaaactga cataaaagaa attgtatttg
    30961 atataagaca agaaaagaat ccttgtgcat tgtgtgctaa tttaagaaga ggtgctttga
    31021 acgataatgc taaaaaactt ggatgtaata aagtagctct tggtcatcat aaagatgatg
    31081 caattgagac atttttaatg tctatgtttt atgagggtag agtaaattgt ttttccccaa
    31141 agacatacct agacagacag gatttaacag ttataagacc tatggtttac atagaagagt
    31201 atatgactaa gaaaatttca aaagattcta actatcctat tatcacaaat ccctgccctg
    31261 caaatggtca tactaggaga gagtacataa aaaatcttat tgctaattta aataaagaga
    31321 tgcctgattt taaaagaaat gtatttggtg ctttaaataa ttctgagaaa ttgtttatat
    31381 gggataaaga gaagataaaa aattttaaat aataattaaa atttttaaat aaaaaagcaa
    31441 gattgtatta attgtaaata atctttatat aatctacaca at
//
LOCUS       DAMJVG010000046        31049 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.046, whole genome shotgun sequence.
ACCESSION   DAMJVG010000046 DAMJVG010000000
VERSION     DAMJVG010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 31049)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31049)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31049
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.046"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(118..654)
                     /locus_tag="PC512_002242"
     CDS             complement(118..654)
                     /locus_tag="PC512_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
                     /protein_id="HDF2441982.1"
                     /translation="MEYKSPVYGIIAVPIEKIESNDYNPNAVAPPEMQLLYKSIKEDG
                     YTMPIVCYYNEEKDKYIIVDGFHRYRVMLENEDIYDRENGLLPVSVIDKSLDERMAST
                     IRHNRARGSHNVDLMSKIITELCEIGKSDEWISKHLGMEVDEILRLKQITGLAYLFKD
                     KEFGNAWIPFGSDIEEEN"
     gene            complement(672..1985)
                     /locus_tag="PC512_002243"
     CDS             complement(672..1985)
                     /locus_tag="PC512_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3440 domain-containing protein"
                     /protein_id="HDF2441983.1"
                     /translation="MDKRYLESDVFEAFQERLSYLFNEFDYIYVSFSGGKDSGLLLNL
                     VLDYKRKNNISSKIGVFHQDFEAQYSLTTEYVEKVFEDNIEDIEPYWVCLPMATRTAV
                     GNYEMYWYPWDDEKEELWVREMPVKEYIINQKNNPFTYYKYKMRQESLAKQFGRWIRD
                     IHEGAKVVCLLGTRAAESLQRYCSIVNKQHGYKGKCWITKEFKNVWTASPIYDWEIED
                     IWLAHYKFDYDYNKIYDLFYKAGVAPRKMRVASPFNDSAKESLNLYRILDPDVWVKLV
                     ARVQGVNFTSIYGKTKAMGYRSVKLPYGHTWKSFTYFLLDTLPENIRNSYIKKFSTSI
                     EFWQNTGGGLSEIVIRELLRKGYKIELNGVSNHTKDKKSRVIFLDDIPDDTDDIKFTK
                     DIPSWKRMCYCILKNDHMCRFMGFGPTKEQRIRTEYIKKKYEKIH"
     gene            2340..2780
                     /locus_tag="PC512_002244"
     CDS             2340..2780
                     /locus_tag="PC512_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HDF2441984.1"
                     /translation="MYERMLDKSNKPCLSQIIEYIGKDGYARLCKLETYLKTQYNLSR
                     ELRFPFGNNYGWGYKYSHKSFHLFYAFFEKGAFTVLIQIGDKQVPAVEKTLVALTPKA
                     KELWVTRYPCGNNGGWIKYRILEDADLLDIIQYIRAKKSPPKQN"
     gene            complement(2965..3153)
                     /locus_tag="PC512_002245"
     CDS             complement(2965..3153)
                     /locus_tag="PC512_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441985.1"
                     /translation="MNKNNNLVIICMFIGMILGMAIGCAIGISKGNVGITMCYGLIFG
                     MIIGICIGTVIKNSNKKE"
     gene            4200..4595
                     /locus_tag="PC512_002246"
     CDS             4200..4595
                     /locus_tag="PC512_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441986.1"
                     /translation="MNILKMKKTGIFLGGVLFGTVGVKILSSDCVKKTCTRATAGALK
                     VKDSVLETTTKIQENVEDILAEAKEINEQEDLSTSKVNVVQDTLKCEQEVLKTETIKT
                     VEDTNSNSIKCEEIKDNVIEEKNSTCTTE"
     gene            4638..6737
                     /locus_tag="PC512_002247"
     CDS             4638..6737
                     /locus_tag="PC512_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HDF2441987.1"
                     /translation="MNFYIKHEIRGRIRFDLQLGKLNNKQSDTLLYYLTSINGITKAK
                     VYDRTGDAVIYYNGEREYIIREITKFSFNNSKIENLVPEHTSRELNNYYRDKLANKLL
                     VKSISKIFFPKSLRFFLIGLHSIKYFKKGLSSLLNKKIEVSVLDATAIGISIFRKDIN
                     TAGSVMFLLGIGELLEEWTRKKSIDDLAQSMSLNIEKVWLRKGDTEILIPISEIKEGD
                     LVSVTMGNMIPLDGVIVSGEAMVNQASLTGESLAVNKKEGSYIYAGTVIEQGNIVMCV
                     KEKAGTTRFQKIVTMIEESEKLKSSVESKFEHLADTLVPYSFLGSILTYAITRNPIKS
                     LSILMVDFSCALKLSIPISVLSAMRECNNNNITVKGGKFLEGVACADTIVFDKTGTLT
                     KAQPTVSDIITFQNYNKEDMLRLAACLEEHFPHSIANAVVYEAEKQGLSHKEMHTEVE
                     YIIAHGISTKVDDKKVVIGSKHFVFEDEKCTIPDGEEDKYNNLSDEYSHLFMAISGKL
                     SAVICINDPLRKEAKYVISNLRECGIKKIVMMTGDSEKTAKSIASKVGVDEYYSEVLP
                     EDKANFVKSEKLKGRKVIMIGDGINDSPAISESDVGIAMSEGAEIAREISDITISADN
                     LNNLIVLKQISNKLMKRVDLSSKFIIGFNLGLILLGVGGFVRPSTSAFLHNASTVGIS
                     LNSMTNLLENTNTYNYH"
     gene            complement(6962..12172)
                     /locus_tag="PC512_002248"
     CDS             complement(6962..12172)
                     /locus_tag="PC512_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosome-binding GTPase"
                     /protein_id="HDF2441988.1"
                     /translation="MANKLYSEIVNLLEEGRDELRKYDLKEKSILLFLGASGVGKSTC
                     INYLKGCVMEEKTDEETGQIYITAKDSAVEIGNGVYSKTLCPEVVDIANRDFSLCDCP
                     GFFDNRGAEYMIAGAMLVRETISTSSKVKGMVVILDYQSLLDSRHTLLIETGKNLKDM
                     LGDYAKYKENFFFLINKIPKTLIGNVTEEKIRNILEKAKEDLDSQEKDYDGCKELVYL
                     LNVALSDGVSIKLCNPLDKQPEKLLDEMKNLPETFEKTDLGLMLTASCKIEIQKAVDV
                     TYKDLEKLLVPYIESVKKGMEDSISILSSINSLKDKKIQLDKMYTDLCSRTNNMKEIM
                     EFVQELSYGDGVQKVNILEETRLLLELNSYCSETHIVGLSELLKSLLKNTLEDTLKDI
                     KYWIAEEEYREEEAKKLEDAEYRIEKIQSCTYIKSYEKENVLSIYIPIPKVNLSDLTK
                     IISGYQLNILSSIYMYGDCELKIDCNMEKEVFSGKNIVLLTEKLHIPEGTYSINVSGK
                     DAEKLVGESSIYDGMNGRNGNNAGTSGDIILSFKEIEKRGELKLYVDGGRGGNGQDGK
                     KGDTGITGEAGANAKIGSKKESKEFANVKGTKYYVVKAEKGKQGGTGGTGGNGGNAGL
                     GSKSGQVYLLGKAPLLKSAISKKDGNHGLAGKGGSGGAGGAGGLGGIRGIYEETIRYI
                     GTSPPMDNSDRNYYYFDRYVFNHALNQKQAADDGEKLNALYEEHKDWIISKREDSGSA
                     GAEGTAGHSGDALKEKELLKQEYSLSIDTFFYEFFERFGFSGIKGYRNLRLLCAVGIL
                     EADILELSHIYEIFHAVEKIEMQLNREILQKYYSFEKKNKAVLSLDDMNTKKEFYKEA
                     KEIYEYLINKLMQSDRIESFVGKNQNFSEWSMILFALEQKTAFYVQMIEESEIGGNRV
                     TDIRSLTDYLDKTLRELEQGKKDELKEGYFNTYKESILTQIESGNQQIEVLKNELENK
                     MLSVNAKMNLLIQEIIKMKEDEQEDIEELKKKQAKLEEQMKTQLILSGIQSALSLLTA
                     FSGVGQACLGAFDSAKSLKENLSAKEEEYKWTNRMVNFSDFKLDSDGMRFVLGEQLSE
                     DRKNALDKMTYNLAGVDEERRTKFDQIKEIIVKSIDDDNYADKADDIQRAKEGLSESE
                     YKEIYTKIQKKEIGMLEANYNNKQQKDKLAALEKSKQAIERQQKTSKIKNALSIGSSA
                     CSLINTAISGVNNCLNVKSSFESKIEVVKEAIKDKENNIKKLDELNTQMVEFKDKTLK
                     ESVIPFVEKFDSTVKNQDIFENEISKLKMKEVLTELSTKFGSLKMENSEEISIIFKKV
                     QDMMETQIIITDKIDKKKDNLAMGELIYQMSDSGNQMNEYQKKLIHQIELNQVRYLCQ
                     VEAAAFQLWTFPFGSNIVNILNRCHVGITEDENEVINQAKEQNRQIREFLDQDAYQWQ
                     KTDNHILKVALTGSLDGKSRVGFENTYSLYDCNEEEVKKLLTGDEISFEVPLNKNFDA
                     IKYVTMYANIPNLRRNILEDSLKVKVHIHLYDSGYFSLYDDKKDVYYQYVFPQNYINI
                     THGLDVKYNDSDSINSIWSSVEDKGIEKFKNAGLNSGRSPYSMAKISLKAHFNKKLSY
                     DSLTNEQKKKLESYFDKPSKYAWSDSIDILKSLGYIDFKGILSKSWYEIKKDIDSDGE
                     IMKHFSILQVDLLERIIYEQTSILKENIPNLTIELVGCGIYVESEFNYLKQNDLKCYE
                     ERLVENTIIG"
     gene            complement(12187..14682)
                     /locus_tag="PC512_002249"
     CDS             complement(12187..14682)
                     /locus_tag="PC512_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2441989.1"
                     /translation="MPENNNQLLEEITLLLNEGKVAINKAENQNLILILGGTGCGKST
                     AINYLAGCVMMEVEDEDTGISYIDCLDPVAEIGSGAVSQTLYPNIVNMRKPIEGMDAK
                     LCDTAGFSDNRGVAHDISAAVSLGEVFKNSASICAVIVLIPEADILDSRLTKVLDLFQ
                     QLNMCLHKENFKGSITFFISKSFLGRTEKQIYNVIKRKYEQLCENLDSNIEEKAWLFE
                     ELLKDNGKNIHLCKPLASDEREGLLKQVLELDEVKDKTSAFQYPISADARLVLDTLIK
                     EIQNNIVSSLEDYVKAYTEDFINIIGSITMIQEIAKYDEVVKVFKNWLESTTSLTIER
                     FINVLAKQSGLFLQDSCMKLQNKIKGNLDIIDALSKYTEHGTGEILLPSVHMEFIIEK
                     ASKKIMEQNFIIIRKNLEKVLVSYEVQKQVFTLPNREKLMEVANKKDYVYSVSDFNSI
                     LTNVTVTQNEELEDSITRLSAYGEEGNEIIREFIGKYILNPFIVKTININDKKGIEIR
                     ALIPNLVISSVLEYFKNRKVDDNVSTFMFFAKDTIYMDDNLGMNFASEKNIILASNNL
                     DVGSNVKINVSGKSGELVDNSMYGKNGEDGRDAGNIYLYIKEEIRNYRLTLIANGGNG
                     SKGIDGENGETGASGSNGADAGYTSYFHGQMFKGYFEKGTSGKKGEKGGAGGNAGRGG
                     NAGKKGNIYFISDSEEQKNRIINHCDITVKDGEAGPNGRPGLGGYGGSGGYHGYNTLS
                     FSPSGIDKTVYYTGYFTSWDYKLDSIIKYHIEFSGGSWNEGKTGPAREYAEYGDRGDN
                     GGFNAPNTKLSTAVSKVEENLIKEKYQGYCSEI"
     gene            complement(15365..15652)
                     /locus_tag="PC512_002250"
     CDS             complement(15365..15652)
                     /locus_tag="PC512_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441990.1"
                     /translation="MRLNVTKQNTIEVENSRKEDVYFVIVDNVFFERQGDVFNSITNN
                     NLNNYDVKILPTDNVFLELKITSTKDLEPVFIVVEDRQYNHGSIMFKPVLV"
     gene            complement(15672..15947)
                     /locus_tag="PC512_002251"
     CDS             complement(15672..15947)
                     /locus_tag="PC512_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441991.1"
                     /translation="MSLFVGGWSKFRAVEEEDLKVFNEAVGMLEGVGYEPLIVSTQVV
                     AGTNFKFICNATSVTNPPQNYLAEIVVFKPLPCDEHNATITSINIIK"
     gene            complement(16584..16763)
                     /locus_tag="PC512_002252"
     CDS             complement(16584..16763)
                     /locus_tag="PC512_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2441992.1"
                     /translation="MGKDRFEKVYSQGKINATEIWVDKETGVNYVFHYYGHAAGFTPL
                     LDREGKPVISPIVSK"
     gene            complement(17048..18523)
                     /locus_tag="PC512_002253"
     CDS             complement(17048..18523)
                     /locus_tag="PC512_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2441993.1"
                     /translation="MKRKPQYLIIFEHIIQQIYTGKITIGDRLDSIKSMSEEYMVSKN
                     TIKTVIKMLSEKGFIETKAGSRPVLIQSTSKQSIESDLLYEKILQISEIYKIFSLIFP
                     SIAMYNIKRFTSKDFEELNEIIDCMEKNSSNYLVFKEQRLKYINKLISKTNNFLIHHF
                     CEIIQHDVIISQLAYNFDNLDNLDNCCIDFFRNKYIEQVRKTYLYGLDGNLIEFKKLL
                     TYMYKACRESILKMVENRAPQSIDTSSFNSVTLEKCYLYDLIVSDVICQIFEGNIKIG
                     DCLPSITSIINRYNVSLPTVRSAYNELNELGIAKTINGKGTYITLFSEYDDDYINTEE
                     GAKRLSLLLDAMEFVTITLEDVVLLLGNKMDLIAVDKIETHLRYLQNNCEECKVYPDF
                     VLLCKIVDYTQIYVLQETFLHLKQYMIFGIYLERFFHEEYNEILKTRFDVCFEILRYL
                     KKGDVERFAESFSNIFKESLQYLKKVISSLNVDMRVKLDIL"
     gene            19592..20770
                     /locus_tag="PC512_002254"
     CDS             19592..20770
                     /locus_tag="PC512_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF2441994.1"
                     /translation="MKYHIFLIITTILIIELCNIYICKIASFRNKNITIHKNYKYIFL
                     IKPLTFLIIIFTKLPLPLYYILFYIVSHKLLLSRKSSTNNHFIPNMAVISFCILHLIT
                     VSTISLVKNTSPDIIFANMTYKLISILIASILDFILWYSMNKIKEHIYIITQNQIEFS
                     LFLKFIWFTLGYILFDSIQITFAPPSSLTSYFILGSNILLILQLIIFINHIYSIEKNI
                     YLEKEHNRLKMIKQEQLLKVNLLKKKANIDELTSAYNRKFAFEKIQHYIDNNLLFSLI
                     YIDLDKLKTINDTYGHLAGDNYIINFSSIVIENLGIDDIFARIGGDEFIVIMPKSNEN
                     TTKEFIEKISKIMDNTISFSYGIVEVSSENKMTVEEIINIADIRMYTNKQNNHKRNNN
                     "
     gene            21120..22001
                     /locus_tag="PC512_002255"
     CDS             21120..22001
                     /locus_tag="PC512_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF2441995.1"
                     /translation="MPAYLFDSNSIANIYRVFPISFSFIVTGLYFSYKNNKNNKINFE
                     AVLEDKKNLIFLLSLMFGMYLYLCLSLSIYYTVGNVLILKLYGIKSAIIVLVGNYIAE
                     RYSFRITQIKGYDIKNQIEYVESVKTEYEINKLNDIVYTDLLTGFYNRPFVNQKLSEW
                     TSNHYKFTLCFTDLNSLKPVNDKFGHQFGDKYISTTAQIIKKLINVENSLLFRYGGDE
                     FLFLLQNTSCVEAEKIMININYELSKISNTDEYPYALSISYGLVEWDGISDIETLISK
                     ADSLMYENKLKNKSTLN"
     gene            22192..22359
                     /locus_tag="PC512_002256"
                     /pseudo
     CDS             22192..22359
                     /locus_tag="PC512_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418025.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
     gene            complement(22619..25186)
                     /locus_tag="PC512_002257"
     CDS             complement(22619..25186)
                     /locus_tag="PC512_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002602373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, phosphate dikinase"
                     /protein_id="HDF2441996.1"
                     /translation="MIYYVLPLEHKQATIEIVGGKGMSLSKLLTAGIPVPDGFHVTTA
                     SYQIFVETNHIQSRINKLLDGIDSNNTSQLEDVSKKIGELFHNGEMPQEVSDAIKMAY
                     AGLGNISVAVRSSATAEDLPDASFAGQQETYLNIQGEDKVIDSVKRCWASLWTARAIA
                     YRVKNNIKHEIVALAVVVQKLAFSDSSGIMFTLNPINGRRSEMIINAAWGLGEAVVSS
                     LVTPDTIVVDKDSERIISYEVANKEIMTVRTSEGTEETMVPERLRKKYALTRNQVMQL
                     IQLGKKIEKYYQMPMDVEWALEKDKLYIVQARPITVLPPEWVLPEQDVVYTKGSLAEH
                     LPNPVTPLFATLGLEIVNRASELLWIDMFGKSAKKLLPKNGAYTVINGYVYLSAKSNP
                     LLIAIKSLSPRSLRRTLMNSVARWETARKGYEDAIKQWEEKPLHTMNAHQIMEGIQTI
                     FYAACIYFTRIQLTLPAASISETLFTKLFQGAVRRAGITDTSVFLLGFDTIVLQSEKE
                     LWGISEWVKQNNSINLYLQNSPAIKIAEDFMSSVVPVGVSQEVWIEWKNRINKYFKEF
                     GRTAYEFDFAHSTPQETLTPTFESVKTFVEGKGESPFLRQTTFEKRRKHAEEEILQHI
                     GGLRKKLFFKLLHWAQETSPMRENAIYLMGMGHPLIRCMFQEISERFIRGGAISHLDD
                     IYWLTKSELEVLIEQLDKNKSLSDMNGIIPVRKAELKKYMGYVSPSKLPEKNKKTISQ
                     AQQKQKDGKIVLTGIGTSTGVVTAPACVLNSPADFESFQPGSVLVAVTTTPAWTPLFS
                     SASAIVTDIGGPLSHSSIVAREYGIPAVMATHIATRAIKSGQMITVDGLAGTVTFDE"
     gene            complement(25189..25794)
                     /locus_tag="PC512_002258"
     CDS             complement(25189..25794)
                     /locus_tag="PC512_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002591427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2441997.1"
                     /translation="MPKGIVLTPEQQAERREKIVAVALSLMAENGFQKTSMREIAVLA
                     NMGKSSLYDFFKTKDEIVVYAVEKEIEKTIQQVHRIIDGEPSPQQCLRKIMLNHLRFP
                     EQYRTVLMWLNTESDYLEEEYRKRLKDARYAYQDIIKSVIDNGVTTGIFRKTDTALVT
                     RLLINSMLSISYTSRPLDSSEKMLDETMNIFLHGIMNDGGE"
     gene            complement(26168..27628)
                     /locus_tag="PC512_002259"
     CDS             complement(26168..27628)
                     /locus_tag="PC512_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HDF2441998.1"
                     /translation="MFNELKTKENVYKNLINGKWVESNSRKPIEIYSPIDNSLVGKVQ
                     SMTKHEVDEVIKNTKESIKVWAEMPVYKRANIFHKAADLLLENIDEIANILVLEIAKD
                     IKSARAEVERTADFLRYTADVGKNMEGEAISGDNFPGGTRNKMSYVSRVPLGTVLAIS
                     PFNYPVNLSMSKIAPALIGGNAVVLKPATQGAISALHVVEIMRKAGIPDGVLNTITGR
                     GSEIGDYVVTHKGINFINFTGSTEVGQHISKISGMVPLLLELGGKDAAIVLEDADLDF
                     AAKNIVSGAYSYSGQRCTAVKRILVQESVADKLVGKIKPLVEKLTIGNPMDEVVITPL
                     IDNKATDFVQGLVDDALHKGAKLITGNVRKNNLFYPTLLDNVNVDMKIAWEEPFGPVL
                     PIIRVKDINQAIEIANQSEYGLQSSVFTSDIDKAFYIADKLEVGTVQINNKTERGPDH
                     FPFLGVKASGMGTQGVKYSIEAMTRPKAVVVNVREL"
     gene            27982..28560
                     /locus_tag="PC512_002260"
     CDS             27982..28560
                     /locus_tag="PC512_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2441999.1"
                     /translation="MAKSFTEIEKDNIRKRLISECEINWSKYGYKKTNIDELCSKSGI
                     AKGSFYTFFDSKEKLFFEVLNGIQNRLISSVDEILSNMPPKEGFAKALKMLYRLYDKN
                     PFLYSPNNTDYITLLNKIPKEMLSQLEYSNVQSFYSLIERHNLKLKIEKEKAFGVCNA
                     LLSSLLLKEDIGYDYIEVFDFMVDNLVEHILE"
     gene            28611..28844
                     /locus_tag="PC512_002261"
     CDS             28611..28844
                     /locus_tag="PC512_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442000.1"
                     /translation="MIELIQRLNDIIYKINDKLNIHTKLVDPSSELMPLYSMLSIIVS
                     IFLIILGIKVRKKFLIIIAIISIIINILIILDR"
     gene            28853..30103
                     /locus_tag="PC512_002262"
     CDS             28853..30103
                     /locus_tag="PC512_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2442001.1"
                     /translation="MVKSSNTFNKNFNLMILGQIISLFGASILKFALSLYILDITGKA
                     EIFATILAVSSIPIIVFSPIGGAIADIFNRRNLMVIFDFSSSLTVLILAVFLFNNNGS
                     ILLVGIIMTILSVISTMYQPTVQSSTPLLVDNEHLMNANGIVAGVASLTNIAGPVLGG
                     VLYGVIGINAIIVISCVSFFLSAIMEIFIQIPFIKQEQNSNIIKTIFTDIKDGIVHIC
                     KENRFILKILFLAIAINLFLSSMLIVGIPYIVKITMGASNFLYGLAEGAISFSSLVAA
                     VSIGIFSKHLKITNLHISFIICAVMFIPMAVSVYPFILNTGFPVPFLIFIVSSMLIFF
                     TTTLISIYVITVTQLKTPNELLGKVMSILFAGTAIAMPLGQVMYGKLFDLLSDRVYII
                     ILGVGFITLLIAFVSKITLRNENL"
     gene            30264..30833
                     /locus_tag="PC512_002263"
     CDS             30264..30833
                     /locus_tag="PC512_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HDF2442002.1"
                     /translation="MSYMPTLEQAWEILRKYNKEEFHIRHAQIVSGVMRYYAKEYDPE
                     RVEFWEIVGLLHDLDFEMYPDEHCVKQRELMTELDLDKSIIDSTISHGYGLTGSDVKP
                     EQFMEKVLFAVDELTGLIGAAAIMRPSKSVSDLELKSVKKKFKDKSFAAGCSRDVIRS
                     GAEMLGWELDKLIQTTIEAMRSLIPEMAI"
BASE COUNT        10486 a         5292 c         3755 g        11516 t
ORIGIN      
        1 taggataatt ttcctactct tttttctgta cttacatata atattaaaac tctttatttt
       61 ttaatatata ttttaaattt tcttttttaa taaatctttt tcttttaata aatctattta
      121 attttcttct tctatatcag agccaaaggg aatccatgca ttaccaaact ctttatcttt
      181 aaataaataa gctaatccag ttatttgctt caatctaaga atttcatcaa cttccatacc
      241 caggtgcttt gatatccatt catcagattt tccaatttca caaagttcag ttataatttt
      301 actcattaaa tccacattat gagaacctct tgcacgattg tgtcgaatag tacttgccat
      361 tctttcatca agagatttat caattactga aacaggaaga agtccatttt ctctatcata
      421 tatatcctca ttttcaagca ttactctata tctatgaaaa ccatctacaa taatatactt
      481 atccttttcc tcattataat aacagacaat tggcattgta tacccatctt cttttatact
      541 tttatacaac aactgcattt ctggtggggc tactgcattt ggattatagt cgttagattc
      601 tatcttttcg attggcactg cgatgattcc atatacagga cttttatatt ccatagcatc
      661 ttaactccta tctaatgaat tttttcatat ttcttcttaa tatattccgt tctaattctc
      721 tgttcttttg taggaccaaa tcccataaat ctacacatat ggtcattttt taaaatacaa
      781 taacacattc ttttccaact tggtatatct ttggtaaatt taatatcatc cgtatcatca
      841 ggtatatcat ccaaaaatat gactctactc tttttatctt ttgtatgatt tgaaactcca
      901 tttaattcta ttttataacc ttttctcaac aattcacgta taactatttc tgacaaacca
      961 ccacctgtat tctgccaaaa ctcaatagat gttgaaaatt ttttaatata gctattcctt
     1021 atattttcag gtaaggtatc aagcaaaaaa tatgtgaaac ttttccatgt gtgtccatat
     1081 ggcaatttaa cactacgata tcccatagct tttgttttgc cataaataga agtaaaatta
     1141 actccttgta ctctagcaac caatttcacc catacatctg ggtccaatat tctgtataaa
     1201 tttaaactct cttttgctga atcattaaaa ggtgatgcca ctctcatttt tcttggagct
     1261 actccagctt tatagaataa gtcataaatt ttattatagt catagtcaaa tttatagtgt
     1321 gctaaccata tatcttctat ttcccaatca tatataggag atgccgtcca gacattttta
     1381 aattccttag ttatccagca ctttccttta tatccatgct gtttattcac aatagaacaa
     1441 taacgttgta gagattctgc tgctcgtgtt cctaataagc aaacaacttt tgcaccttca
     1501 tgtatatctc taatccatct accaaattgt tttgccaaac tttcttgtct cattttatat
     1561 ttataataag taaaaggatt atttttttga tttattatgt attctttgac tggcatttcc
     1621 cttacccata actcttcttt ctcatcatcc catggatacc aatacatttc ataatttcct
     1681 acagcagttc ttgtagccat tggtaaacac acccaatatg gttcaatatc ttcaatatta
     1741 tcttcaaata ctttttcaac atattcagta gtcaaactat attgagcctc aaaatcttga
     1801 tgaaatactc ctattttgga acttatatta ttctttctct tataatccaa aactaaattt
     1861 agcagtaaac cactatcttt tcctccgcta aaagatacat agatataatc aaattcatta
     1921 aaaagataag aaagtctttc ttgaaaagct tcaaatacat cggattctaa atatctctta
     1981 tccatttgaa ttatcccctt tcaattagaa gtttataaaa ccttacaatg caatattatt
     2041 atgctttttt agcagtaatc agcataaatt atacattatt taaatacaca aatccaacta
     2101 actacatata attataatgt aattatactt ttgtattata aactatattt tatcattatt
     2161 ttacattttt ttccaatata tataaatatc atatttttct attagctaaa actaattact
     2221 ttatatttct acgtattagt ataataatac ataaaaactt gaataatgca taaaaacttg
     2281 acatactgtt gtcataatta ctttgctata attaaaagta aaaatggagg taaattctaa
     2341 tgtatgaacg tatgcttgat aaaagcaata aaccctgttt gtctcaaata atagaatata
     2401 taggtaaaga tggatatgca cgattgtgta agttggaaac ttacttgaaa actcaatata
     2461 atttatcaag agaacttcga tttccttttg gaaacaatta tggttggggt tacaaatata
     2521 gccataaatc ttttcattta ttttatgctt tttttgaaaa aggtgcattt actgttctga
     2581 ttcagatagg tgacaagcaa gttccagcag tagaaaaaac gttggtagct ttgacaccaa
     2641 aagctaaaga gctctgggtc actcgttatc cttgtggcaa taatggaggc tggattaagt
     2701 atcgtatttt agaagatgca gacttacttg atattattca atatataaga gcaaaaaaat
     2761 ctccacctaa acaaaattaa cttttatttt ttgtgattta aatatagtgt atataaattc
     2821 cattctttcc atataaaaaa aataatataa aaaatatcta ttagtataac ttatttagta
     2881 tgtcttattc tactttttac agataattaa aaagttttat cataaataaa tcataactag
     2941 acatcctagt aaatcaaaat taatttattc ttttttatta gaatttttga taacagtccc
     3001 tatacatatg ccaattatca ttccaaaaat tagaccataa cacattgtga tacctacatt
     3061 tcctttagaa atacctatag cacaacctat agccattcca agtatcatgc ctataaacat
     3121 acatataata actaaattgt tgtttttatt catagttttc tccattcaat atattttaaa
     3181 ttgcctagct cgccttctta gcttaaaaca aagaaatata aattaacttt ctttcattct
     3241 aatatctgct tgtataaatg tcaaacaaca catttcttgt cataacctcc tctttttgaa
     3301 gtaagtacaa tctcccagac gcaataatat caatttccta aaaccattta agtaactttt
     3361 atatttacat aatatttaca atcataaact atatttttat tcatttatac atcataaaca
     3421 ctccctacta atcattatta tacttaaaat aatgttcatt tataataata tatctaacac
     3481 actttaattg aaaaaaataa aactttgcct ttcattccca tatataaata agtatacttt
     3541 ttgatgctct attacaaatc aactaaatta attgatataa attatcattt tctgttgaaa
     3601 ataccattcg cacatgctat acttaattgc ataaatggta ataaatgtca tatgatttta
     3661 caaatctatt aataacaatt attactttta ctgtatttta aattttttgg actaaatatc
     3721 aagaactttc taaaatacaa agtacaaaaa atttatataa gttataaatt tatatgaact
     3781 agataagctc aaacaatatg ttatgtataa actgtgtagt attcggttat aaatttatat
     3841 aaattatata agctagataa agtattacct caactatata agctagatat ataaattgca
     3901 tatataagct atataagaat tatttcaact atataaacta catatgtaaa ttatatacat
     3961 aagctagata tataaactag atatataaac tagatatata aactgcatat ataagctata
     4021 taagaattat ttcaactata taaactacat atgtaaaatt catgtaaatt tactaatata
     4081 aatcaaataa aattactaaa ctctctaaac taattttgta aaacatactc tatttttaac
     4141 atttgttacc ttatacataa gtacaaacaa aatctaacta aatgaaagga taatgtaaaa
     4201 tgaatatttt aaaaatgaaa aaaacaggga tatttttagg aggagtactt tttggtactg
     4261 taggtgttaa gatactttca agtgattgtg ttaaaaaaac ttgcactcgt gcaacagcag
     4321 gagcattgaa agttaaagat tctgttcttg aaacaactac gaaaattcaa gaaaatgtag
     4381 aagatatttt agctgaagca aaagaaatca acgagcaaga agacttatct acatctaagg
     4441 taaacgttgt acaagatact cttaaatgcg aacaagaagt tcttaaaact gaaactataa
     4501 aaactgtaga agatactaat tctaatagca ttaaatgtga agaaatcaaa gataacgtaa
     4561 ttgaagaaaa aaatagtact tgtacaacag aatagattta atgattatta tgattaataa
     4621 tatcaggagg aagtaaattg aatttttata taaaacacga aataagaggt cgtatacgct
     4681 ttgacttaca acttggcaaa ttaaacaaca agcagtccga tactctctta tattatttaa
     4741 cttctataaa tggtattacc aaagcaaaag tttacgatag aactggtgat gcagtcattt
     4801 attacaatgg tgaaagagaa tacataataa gagaaatcac taaattcagt tttaacaata
     4861 gcaaaataga aaacctagtt cctgaacata ccagcaggga attaaacaat tattatagag
     4921 acaaattagc aaataaactg ctagtcaaaa gtatctccaa aatatttttt ccaaagtcct
     4981 taagattttt tttaattgga cttcattcta taaaatattt taaaaaaggt ctctcttccc
     5041 tgctaaataa aaaaatagaa gtttctgttt tagatgccac tgctataggt atttctattt
     5101 ttagaaaaga tatcaatacg gctggttcag ttatgtttct tcttggtatc ggtgaactat
     5161 tagaagaatg gactagaaaa aaatctatag acgacttggc tcaaagtatg tcactaaaca
     5221 ttgaaaaagt atggttaaga aaaggtgaca ctgaaatcct aattccaatt tcagagataa
     5281 aggaaggaga tttagtaagt gtaactatgg gaaatatgat tccattggat ggagttatag
     5341 tatcaggaga agcaatggtc aatcaggcat cacttacagg tgaatccctt gcagttaaca
     5401 aaaaagaagg atcttacata tatgctggaa ctgtaataga gcaaggcaat attgttatgt
     5461 gcgtcaagga aaaagctggt actactagat tccagaaaat agtaactatg attgaggaat
     5521 ctgaaaaact aaaatcttct gtagagagta aatttgaaca tctagcagat acattagttc
     5581 catacagctt tttaggaagt atattaacct atgcaattac tagaaaccct ataaaatcac
     5641 tctctatatt aatggtagat ttctcttgtg cattaaaact ctctatccct atttcagtac
     5701 tatcagccat gagagaatgt aacaataaca acattactgt aaaaggtgga aaatttcttg
     5761 aaggtgttgc atgtgcagat actattgtat ttgataagac aggcacatta acaaaagctc
     5821 aaccaactgt ttcagatata attacattcc aaaattataa taaggaggat atgttaagac
     5881 ttgcagcttg cttagaagaa cacttcccac actccatagc aaatgcagta gtttatgaag
     5941 ctgaaaaaca agggcttagt cacaaagaaa tgcatacaga agtagaatat attattgctc
     6001 atggcatttc aacaaaagtt gatgataaaa aggttgtaat aggtagcaaa cattttgtat
     6061 ttgaagatga gaagtgtact atcccagacg gtgaggagga taagtacaat aatctatcag
     6121 atgagtattc acacctattt atggcaatat caggtaaatt atcagcagtt atttgcataa
     6181 atgacccttt acgaaaagaa gcaaaatatg taatttcaaa tttaagagaa tgcggaataa
     6241 aaaagattgt gatgatgact ggagatagcg aaaaaacagc taaatctata gcaagtaaag
     6301 ttggtgttga tgaatattat tcagaagtct taccagaaga caaagccaat tttgttaaaa
     6361 gtgaaaaact caaaggtcgc aaagtaatta tgattggtga tggaatcaat gattctcctg
     6421 ctatttcaga atcagatgtc ggaattgcaa tgagtgaagg tgctgaaata gcaagagaga
     6481 tttcagatat taccatatca gcagataatt tgaataattt aatcgtttta aagcagatta
     6541 gtaataagct tatgaaaaga gttgatttaa gttctaagtt tattatcggc tttaatttag
     6601 gtttgatttt acttggtgta ggtggatttg ttagaccaag tacatctgcc tttttacaca
     6661 acgcatctac tgtcggaata agtttaaaca gtatgacaaa tttattggaa aacaccaata
     6721 cttataacta ccattaatct ccattacata aaacatatga tataaaaaat ttataattca
     6781 tctttttaaa aaaatatgtc ttaaaattag cttttttcta atcaaaatta tataaagcat
     6841 actttacaaa ttttaaactc aacttatttc tattttttac aaaaaaggag atgattcaaa
     6901 ttttcatttt gaaacatccc cttttgtaaa tttctttaaa atttatatat taattatatt
     6961 ttcaaccaat aattgtattt tcaaccaatc tttcttcata gcattttaaa tcattttgct
     7021 ttagataatt aaattcagac tctacataaa taccacagcc taccaattca attgtcaaat
     7081 taggtatatt ttcctttagt atactagtct gctcataaat aattctttcc aataaatcaa
     7141 cttgtaatat agaaaaatgc ttcataatct ccccatcact atctatatct ttcttgattt
     7201 cataccaact ctttgacaaa attcccttaa aatcaatata ccctagactc ttcaatatat
     7261 ctatactatc gctccatgca tacttactag gtttatcaaa gtatgactct agtttcttct
     7321 tctgctcatt tgtaagtgaa tcataagaaa gcttcttatt aaaatgtgcc ttcaaagaaa
     7381 tcttagccat agaatatgga cttctaccag agtttaatcc tgcatttttg aacttttcaa
     7441 ttcctttatc ttctactgaa gaccatattg agtttattga atctgaatca ttgtatttaa
     7501 catcaagacc atgtgtaata tttatatagt tttgtggaaa tacatattga taatagacat
     7561 cttttttatc atcatataga gagaagtatc cactatcata taaatgaata tgcaccttta
     7621 cttttaaact atcctctaaa atatttcgtc taaggttcgg gatatttgca tacatggtta
     7681 catattttat ggcatcaaag tttttattta atggaacttc aaaactaatt tcatctcctg
     7741 tcaaaagctt tttcacttct tcttcattac aatcatatag agaatatgta ttttcaaatc
     7801 ccacacgtga tttcccatct aaactgcctg ttaatgctac cttcaaaata tggttatctg
     7861 ttttttgcca ttggtaagca tcttggtcaa gaaactctct aatctgtcta ttttgctctt
     7921 tcgcctgatt tataacctcg ttttcatctt ctgtaatccc tacatggcat ctatttaaga
     7981 tatttactat attgcttcca aatgggaatg tccatagttg aaaagctgct gcctcaacct
     8041 gacacaagta tctaacctga tttaattcaa tttgatggat aagttttttc tgatattcat
     8101 tcatctgatt accactatct gacatttgat aaatcaattc tcccattgca agattatctt
     8161 ttttcttatc aatcttatca gtaatgataa tttgagtttc catcatatcc tgtacttttt
     8221 taaatattat agaaatctcc tctgaatttt ccatttttaa gcttccaaac tttgtgctta
     8281 attcagttaa aacttccttc atctttaatt tacttatctc attttcaaaa atatcttgat
     8341 ttttaactgt actatcgaat ttttctacaa atggtataac agattctttc aaagttttat
     8401 ctttaaattc caccatttga gtattcaatt catctaattt cttaatatta ttttctttat
     8461 ctttaattgc ctctttaact acctctattt tactctcaaa actagatttt acattaagac
     8521 aattattaac accactaatc gcagtattta taagagaaca agcagaactt ccaatactca
     8581 atgcattttt aattttagat gtcttttgct gtctttcaat agcttgttta cttttctcta
     8641 gtgcagctaa cttatctttt tgctgtttat tattgtaatt tgcctccaac atacctattt
     8701 cttttttctg gatttttgtg taaatttcct tatactcgct ttcacttaac ccctcttttg
     8761 ctctttgaat atcgtcagct ttgtctgcat aattatcatc atctatagac ttaactataa
     8821 tctccttaat ttggtcaaat ttagttcttc tttcttcatc aacacctgcc aaattataag
     8881 tcattttatc taaagcattt tttctatctt cacttagctg ttctccaagt acaaatctca
     8941 taccatcaga atccaattta aaatctgaaa aattaaccat cctgttagtc catttgtatt
     9001 cctcttcttt agctgaaaga ttttccttca aagattttgc actgtcaaat gcccctagac
     9061 aagcttgacc aacaccacta aatgcagtca gtaaactcaa tgcgctttgt attccagaaa
     9121 gaattaactg tgttttcatt tgttcctcaa gttttgcctg tttctttttt agttcctcta
     9181 tgtcttcttg ttcatcttct ttcatcttta taatttcttg aatcaacagg ttcatttttg
     9241 cattaacaga aagcatttta ttctcaagtt cattttttaa aacctctatt tgttgatttc
     9301 cagattcaat ttgagttagg atactttcct tatatgtatt gaaatatcct tcttttaact
     9361 catctttctt cccttgttcc aattctctta aggtcttatc cagataatct gtcaaagaac
     9421 gaatatctgt aacacgattt cctccaattt cactttcttc aatcatctgc acataaaatg
     9481 ctgtcttctg ctcaagtgca aataaaatca tactccattc gctaaaattc tgattttttc
     9541 ctacaaaaga ttctattcta tcagactgca tcaatttatt tataaggtat tcatagattt
     9601 cctttgcttc tttataaaat tctttctttg tattcatatc atccagagaa agtactgctt
     9661 tatttttctt ctcaaaacta tagtacttct gaagtatttc tctatttaat tgcatctcta
     9721 ttttctcaac tgcatgaaaa atttcataaa tatgtgaaag ttctaaaata tcagcttcta
     9781 aaattcctac tgcacacaac agtctaagat ttctataacc tttaattcca gaaaaaccaa
     9841 atctctcgaa aaattcatag aagaatgtat ctattgacaa agaatactcc tgctttaaca
     9901 attccttttc ttttagtgca tctccagagt gaccggctgt tccctctgct ccggctgaac
     9961 ctgaatcttc acgtttgcta attatccagt ccttatgttc ttcataaaga gcatttaatt
    10021 tctctccatc atctgctgct tgcttctgat ttaaagcatg attaaacaca tatctatcaa
    10081 aataatagta gtttctatca ctattatcca ttggaggaga ggtacctata tatcttattg
    10141 tttcttcata tatacctcta attccaccaa gacctcctgc accaccagct cctccagagc
    10201 ctccttttcc tgctaaacca tgatttccat cttttttact tatagcactt tttaataaag
    10261 gagcttttcc aaggagataa acctgtccag acttgcttcc aagacctgca tttccaccat
    10321 tacctcctgt gcctccagtt ccaccttgtt ttcctttttc tgcttttacc acatagtatt
    10381 ttgtaccttt aacattagca aattcttttg actctttttt agaacctatt ttagcatttg
    10441 ccccagcttc tccagttatc cctgtatctc ctttttttcc atcttgtcca tttccaccac
    10501 gtccaccatc tacgtaaagt ttaagttctc ctcttttttc tatttcttta aaagataata
    10561 tgatatcacc tgaagtacct gcattattgc catttcttcc attcattccg tcgtaaatag
    10621 aactttctcc aaccaatttt tctgcatcct taccagatac gttgattgaa taagtccctt
    10681 ctggtatatg taatttttct gtaagtagta caatattctt acctgagaag acttctttct
    10741 ccatattaca gtcaattttc aactcacaat ctccatacat atatatagat gacaaaatat
    10801 taagttgata accagatatt attttagtca aatccgataa attcacttta ggtataggaa
    10861 tatatataga aagtacattt tctttctcat atgattttat atatgtacaa ctttgaatct
    10921 tctctatcct atactctgca tcttcaagct ttttggcttc ttcttcccta tattcttctt
    10981 ctgctatcca atatttgata tcttttaatg tatcttctaa agtatttttt agcaatgatt
    11041 ttaacaactc acttagacca acaatatgag tctcactaca gtaactattt aactctaaaa
    11101 gaagacgtgt ttcttctaat atattcactt tctgtacgcc atcaccatat gaaagttctt
    11161 gtacaaactc cataatctct ttcatattat tagtcctact acataaatct gtatacatct
    11221 tatctaattg aatcttttta tcttttagac tatttataga agatagaatg gaaatagaat
    11281 cttccatacc ttttttaaca ctttctatat aaggaactaa aagtttttct aggtctttat
    11341 aggttacatc aacagctttt tgtatttcta ttttacaaga agcagtaagc atcaacccca
    11401 aatctgtttt ttcaaatgtt tcaggtagat ttttcatttc atccaacaac ttttctggct
    11461 gtttatctag tggattacat aatttaatag atacaccatc tgataatgct acatttaata
    11521 agtacactaa ttccttacaa ccgtcgtaat ctttctcttg actatctagg tcttcttttg
    11581 ctttttccaa tatatttctt attttttctt ctgttacatt accaattagt gttttaggta
    11641 ttttattgat aagaaagaag aaattttctt tatactttgc ataatcacca agcatatctt
    11701 tcaaattttt gcctgtttct atcaataatg tatgtctaga gtccagtagg gattgatagt
    11761 ctaaaataac taccatccct tttacctttg aagatgtgga aatagtttcc cttacaagca
    11821 tagcaccagc aatcatatac tctgctccac ggttatcaaa aaaacctggg caatcacata
    11881 atgaaaaatc tctatttgca atatctacaa cttctggaca taaagtctta gaatatacac
    11941 catttccaat ttcgacagct gaatcttttg cagttatata tatttgtcca gtctcttcat
    12001 ccgttttttc ttccatcaca cagcctttta aataatttat acaagtactc tttccaacgc
    12061 ctgaagcacc taagaataac aaaattgact tttcttttaa gtcatatttt ctaagctcgt
    12121 ctcttccttc ttccaaaagg tttacgattt cactataaag tttatttgcc atacatccat
    12181 ccctttctat atttcggaac aatagccttg atatttttct ttaataagat tctcttctac
    12241 ctttgaaaca gctgttgata acttagtgtt tggagcatta aatcctccat tgtctcctct
    12301 atctccatat tcagcgtatt ctcttgctgg tcctgtttta ccttcattcc agcttccacc
    12361 actaaattct atatgatatt taattatact atctaactta taatcccaac ttgtaaaata
    12421 tcctgtatag tatacagtct tatctatacc acttggagaa aatgaaagtg tattatatcc
    12481 gtgatagcca ccacttcctc catatccacc taaacctggt ctaccatttg gacctgcttc
    12541 tccatctttc actgttatat cacaatgatt aattattcta tttttttgtt cctctgaatc
    12601 tgaaatgaag taaatattac ctttcttacc agcatttcca cctcttccag catttccacc
    12661 agctccacct ttttcacctt ttttgccact tgtacctttt tcaaaatacc ctttaaacat
    12721 ctgtccgtgg aaataacttg tatatcctgc atcagctcca ttacttccag aagctcctgt
    12781 ttcaccattt tccccatcta ttcctttaga accatttcct ccatttgcaa tcagtgttag
    12841 acgataattt ctaatttctt ctttaatata taagtaaata ttacctgcat ctctaccatc
    12901 ttcaccattt ttcccataca tagaattatc tacaagttct ccgctctttc cacttacatt
    12961 aatttttaca ttactaccta catcaagatt gttagaagca agaataatat ttttctctga
    13021 tgcaaagttc attccaaggt tatcatccat ataaatagta tctttagcaa agaacataaa
    13081 tgtagaaaca ttgtcatcta cttttctatt tttgaaatat tccaatacac tgctaattac
    13141 taagtttgga attaatgctc ttatttcaat acctttctta tcattaatat taattgtttt
    13201 tactataaat ggatttaaaa tgtatttacc aataaattct ctaattatct cattaccttc
    13261 ttctccatat gcacttaatc ttgttatact gtcttctaac tcttcatttt gtgtaactgt
    13321 aacatttgtc aaaattgaat taaaatcact tacactatat acataatcct ttttatttgc
    13381 aacttccatt aatttttctc tatttggtaa tgtaaatacc tgtttttgca cttcataaga
    13441 aactaaaact ttttctaaat tctttcttat tataatgaag ttttgttcca ttatcttctt
    13501 acttgccttt tctataataa attccatatg tacagaaggt aataaaattt ccccagttcc
    13561 atgttctgta tatttactta aagcatcaat tatatctaag tttcctttta tcttattttg
    13621 taatttcatg caactatctt gtaagaataa tccactttgt ttggctaata cgttgataaa
    13681 tctctctata gtaagacttg ttgtactttc caaccagttt ttaaatactt ttacaacctc
    13741 atcatatttt gctatttctt gaatcattgt tatacttcca ataatattga taaaatcttc
    13801 tgtatacgcc ttaacataat cttctaggct agatacgata ttgttttgaa tttcttttat
    13861 caacgtatct aaaactaatc ttgcatctgc actaattgga tattggaatg ctgatgtctt
    13921 atctttaact tcatctaatt ctagtacttg ctttaataag ccttccctct catctgatgc
    13981 aagtggctta caaagatgaa tattttttcc attatctttt agcaattctt caaataacca
    14041 agctttttcc tctatattac tgtctaaatt ttcgcataat tgttcatatt ttctttttat
    14101 aacattatat atttgttttt ctgttcttcc taagaaactt tttgaaatga aaaaagttat
    14161 actaccctta aaattttctt tatgaagaca catatttaac tgttggaaca ggtctagtac
    14221 ttttgtaagt ctagaatcta atatatctgc ttctggtatc aatacaatta ctgcacatat
    14281 agatgcagaa tttttaaata cttcacctaa tgaaactgct gcactaatat catgggctac
    14341 tcccctattg tcgctaaaac ctgcagtatc acataatttt gcatccattc cttctattgg
    14401 ttttctcata tttacaatgt tcgggtataa agtttgagaa acagctcctg aaccaatctc
    14461 tgccacaggg tctaagcaat caatatatga tataccagta tcttcatctt ctacttccat
    14521 cattacacat cctgcaagat agttaattgc agtacttttg ccacatcctg tcccaccaag
    14581 aattagaatt aaattttgat tttcagcctt atttattgct acttttcctt catttaataa
    14641 gagtgttatt tcttctaaaa gttgattgtt attttctggc atttattttc ccccttggtt
    14701 atatatttta tttaaataaa gtttaatccc ttaagtagat tgcaaagttt ttatactata
    14761 tttaaatttg ttttttattt tttattttta ataaatttgc attttcacta aatttgtatt
    14821 ttcactcaat aattattctt ctttgtttat taaaataact gtgttgtata atataatctt
    14881 tatcaacaca gttattttat ttaatgcgct tattttattg tattttatgt aatacagttg
    14941 ttttttatat tatatgtcca ttattttcct gtggttatta catatagatt tttaattata
    15001 tttgtaccat taatttaaac attcctatac tactgcttaa gttttacacc tataccagct
    15061 tgaatatttt atttttattt gcttaaatag ttcaactata ctggtttaaa taggttatct
    15121 ttatttgctt aaatagttca actatactgg tttaaatagg ttatctttat ttgcttaaat
    15181 agttcaacta tactggttta aataggttat ctttatttgc ttaaataagt tcaactatac
    15241 tggtttaaat aggttatctt tatttgctta aattagttca actatactgg tttaaatagt
    15301 tttcctttag tttaaataat tcacctatac ctacttgaat agttcacttt tatttgctta
    15361 aattctatac caatactggc ttaaacatta tactaccatg attgtattgt ctatcttcaa
    15421 ctacaataaa aacaggttct aaatctttag tagatgttat ttttaattct aaaaaaacat
    15481 tatcagttgg taatattttt acatcataat tatttaaatt attattcgtg atactattaa
    15541 atacatcacc ttgacgttca aaaaaaacat tatcaactat tacaaaataa acatcttctt
    15601 ttctactatt ttcaacctct atagtatttt gtttagttac atttagtctc atcttccacc
    15661 tcctattaat attacttaat tatattaata cttgtaattg ttgcattatg ttcatcacaa
    15721 ggaagaggtt taaaaacaac tatctctgct aaataattct gtggaggatt tgtaactgaa
    15781 gtagcattac aaataaattt aaaatttgtt cctgctacaa cttgagtaga aacaataagt
    15841 ggttcataac caaccccttc taacattcct acagcttcat taaatacttt taaatcttct
    15901 tcttcgacag ctctgaattt tgaccatcca ccaacaaaaa gactcatata aaaacctcct
    15961 ttatatatat atttatttat atatatagta gtaccaattt tctcaatatt caatattttc
    16021 tgtgtaactg gtcaatgaaa atgcataact ggataaaaat acttataaaa taacttaact
    16081 ttacatataa atagcttaat ttacatgtaa taagattatt ctacaatatg aaatacatct
    16141 tattttgaat atattctaaa tacaataatg gatattttca attattatac ttagaaaata
    16201 tccattactt aatttgtttt atttaaaatc acatagagac tttattattt tttttattgc
    16261 atgaatagct atttcaggta tcataaggtg atataccccc tccttgaaac cacaaaaaac
    16321 ataacaaact ttacgaatct tgtcttaaaa gaccacaggt acattcctta tttgtggatt
    16381 ggagtagcca taacaagcaa attttacaat ttttatgatg acaaaaatca ataaaatcgc
    16441 ttagtatata acacgaaata ctacttgttg ctattaagaa tagttagata ggaagtatgc
    16501 attataccaa taaaggaatc aataaagaaa gttaaaacat ccctacaaat taaaaatctg
    16561 ttacattttt ctatatttaa acgttattta cttacaattg gagaaataac aggttttcct
    16621 tctcggtcaa gtaaaggcgt aaatccggct gcatggccat aatagtggaa tacatagttc
    16681 acacctgttt ctttatccac ccaaatctcc gttgcattta tttttccttg tgaatatact
    16741 ttttcaaatc tatcttttcc cattttataa tcctccatat ttttgattgg tctatgcctt
    16801 cttcacttaa gtagaaaaaa tacataactt atttttttaa ttctaatatg agcacgtaaa
    16861 aatgtcaaac agcttattta atttcataac ttcatgttac tgttcgtaac cttgtctgtt
    16921 tacttacact gcattacagc accattttat cctttacatt attgtattgc acacagtaaa
    16981 aatgcttact ttattggatt tttcaactaa aaaaaggatt ttttctccac agaacattta
    17041 ctatttttta taatatatct aattttactc tcatatcaac atttaatgaa gatataacct
    17101 ttttcaaata ttgtaaagac tccttaaaaa tattagaaaa agattctgca aatctctcaa
    17161 catctccttt ttttaaatac ctaagtatct caaaacatac atcaaaacgt gttttcaaaa
    17221 tttcattata ttcttcatga aaaaatctct ctaaatagat tccaaatatc atatattgtt
    17281 ttaaatgtaa aaatgtttcc tgtaatacat aaatttgtgt ataatctact atcttacaaa
    17341 gtaaaacaaa atctggataa accttacact cttcacaatt attttgtaag taccttaaat
    17401 gagtttctat tttatctaca gctatcaaat ccattttatt tcctagtaaa agtactacat
    17461 cctcaagagt aatcgtaaca aactccatag catccaaaag caaactcaac cttttagctc
    17521 cttcttctgt atttatataa tcatcatcat attcagaaaa aagtgttata tatgttccct
    17581 tgccattaat tgttttagca attcccaatt catttagctc attataggca cttctaactg
    17641 ttggaagaga tacattatat ctattaatta tcgaagtaat tgatggtaga caatctccta
    17701 ttttaatatt gccttcaaaa atttgacaaa ttacatctga aacaattaag tcatataaat
    17761 aacatttttc caacgttaca gaattaaaac tacttgtatc tatactttgt ggagcacgat
    17821 tttctaccat tttaagtatg gattctctac aagctttata catatatgtt aatagttttt
    17881 taaattcaat tagattcccg tccaatccat ataagtaagt ttttcttacc tgctctatgt
    17941 atttattacg aaaaaagtct atacaacaat tatccaagtt atccaagtta tcgaaattat
    18001 aggccaattg tgaaataatg acatcatgct gaataatctc acaaaaatgg tgaatcagga
    18061 aattatttgt tttacttatt agtttattta tatattttag cctttgttct ttaaagacta
    18121 aataattaga actatttttt tccatacaat cgataatctc gtttaattct tcaaagtctt
    18181 tagatgtaaa tcttttaata ttgtacatag caatagaagg aaatattaaa ctaaaaatct
    18241 tatatatttc tgatatttgt aaaatcttct catataataa gtcagattct attgattgtt
    18301 tactcgtact ctggattaaa actggtctag aaccagcttt tgtctctata aagccctttt
    18361 ctgagagcat ttttattaca gtttttatag tattttttga taccatatat tcttctgaca
    18421 tgctttttat agaatcaagc ctatctccaa tagtaatttt accagtataa atttgttgaa
    18481 ttatatgctc aaaaataatt aaatattgtg gttttctctt catatttttc ctcttcgata
    18541 aattagattt attgtttttt gtaaggtata tttactttta tttaataggg caaaatagtt
    18601 gcttattttt tcctcataat ctataattaa tatagaccat ttatatatat ggtctaagtt
    18661 ttataatact gtaatgcagt aaaatagcat attgtagcta tactacagca aattaacata
    18721 ccattgtagt atattaattg gaataatttt aagtacttca aaattccagc aaaacatata
    18781 tgtgtttttg atattatgta tattcgttaa tagaatagct atacttgttt tacataataa
    18841 attatatgat acttgctata tgtaattact atatttaata cacataacta ttatacttac
    18901 tatatgtaat tactatattt gatacacata attattatac ttactatata taattactat
    18961 acttggacac ataactatta tacttgctat atgtaattac tatactttat acacatagtt
    19021 attatacatg ctatatataa ttactacact tggacacata actactatat ttactatatg
    19081 taattatact atacgtggac atatagttat catacatact atatgtaatt actatacttg
    19141 gacacataac tattatattt gctatgtgta attatactat acttggacat atagttatca
    19201 tacatactat ataattacta tacttggaca cattatcata catactatat gtaattacta
    19261 tacttataca catagttatc atatatacta tatataatta ctatacttgg acacatagtc
    19321 atcatacatg ctatatgtaa ttactatact tatacacata actattatac tttccataca
    19381 taattactat atttggacac atagttatca tacatactgt atattaagat ataatacttt
    19441 ttaaatttta tataacacag acacatgcaa taaaaaagaa ggtatccata ataagctctt
    19501 tgcatgtacc taaataaaaa ctgtaaaata gaatatataa aatctaatct attttaagta
    19561 aatacaattt cactttaaaa gaggatgtac tatgaaatac catatatttt taatcataac
    19621 tactatatta ataatcgaac tatgtaacat ttacatatgc aaaatagcat cttttagaaa
    19681 caaaaatata actatacata agaattacaa atatattttt ttaataaaac cattaacctt
    19741 cttgataata atattcacaa aattaccatt accactatat tatatattgt tttacatagt
    19801 aagtcataaa ttgctcttaa gcagaaaaag ttctactaac aaccatttta ttcccaatat
    19861 ggcagtaata agtttttgta ttttacacct tattactgta agtacaatat cacttgttaa
    19921 aaatacaagt ccagatataa tatttgcaaa tatgacctat aagttaatta gtattttaat
    19981 agcttctatt ttagatttta tcttatggta ctctatgaat aaaataaaag agcatattta
    20041 tataataact caaaatcaaa tagagttcag tctattttta aaatttatct ggttcacttt
    20101 aggatatata ttatttgata gtatacaaat tacatttgct ccaccaagtt ctctaacttc
    20161 ctactttata ttgggaagta acatattatt aatcttacaa ctaattatat tcatcaatca
    20221 tatatattcc attgaaaaaa atatttattt ggaaaaagaa cataatagac taaaaatgat
    20281 aaaacaagaa caattactaa aagtaaattt attaaagaaa aaagccaaca ttgatgaatt
    20341 aacatcagca tataatcgaa aatttgcttt tgaaaaaata cagcattaca ttgataacaa
    20401 tttattattt tcattgatat atatcgattt ggataaatta aagacgataa atgatacata
    20461 tggacattta gctggggata actatattat taacttctca agtatagtta ttgaaaactt
    20521 aggaatagat gacatatttg ctagaatagg aggagatgag tttatagtta ttatgcctaa
    20581 atctaatgaa aacaccacaa aagaatttat agagaaaata agtaaaatta tggataatac
    20641 gatatctttt agctatggta ttgtagaagt ttctagcgaa aacaaaatga ctgtagaaga
    20701 aattattaat attgctgata ttagaatgta cactaataaa caaaataatc ataaaaggaa
    20761 caataactaa aatgaatatt tacatgagct tacttgtagt ctcactatgt tttttatctt
    20821 attatctcta tcattataat ttttttaaat atctggacat aatgattaat aactctaaaa
    20881 ataaatacac agtatatatt atatattcta tatttaatta tttaattttt attatttgta
    20941 cttatttaaa gtttcatcta attataaatt ggacaatttt tatgttgatt ttattcatac
    21001 aaattaaagt aacttataaa atctccacaa taaaaaacat tttttattca ctaaactgct
    21061 ccatcattgg tttagcaata aatatatttt ttaggtcttt aatgtcaata gtgttaaata
    21121 tgccagcata tttatttgat agtaattcta ttgcaaatat ttacagagta tttcctatat
    21181 catttagctt tatagttaca ggactatatt tcagttataa aaataataaa aataataaga
    21241 ttaactttga ggcagtttta gaggacaaaa aaaacttaat tttcttattg agccttatgt
    21301 ttggaatgta cttgtatcta tgtttgagtt tgtcaatata ctatactgtt ggaaatgtat
    21361 tgattttaaa attatatgga atcaagtctg ccataatagt tttggtaggt aactatattg
    21421 cagaaagata tagctttaga attactcaaa taaaaggtta tgatattaaa aatcaaatag
    21481 aatatgtaga aagtgtaaag acagagtatg agattaataa attgaatgat attgtatata
    21541 cagatttact gacaggtttc tacaatagac cttttgtgaa tcaaaaacta tcagaatgga
    21601 catcaaatca ctacaaattt accttatgtt ttactgattt aaatagctta aaacctgtaa
    21661 atgataaatt tggacaccaa tttggtgata aatacatatc cactactgct caaataataa
    21721 aaaaacttat aaatgtagaa aattccttac tatttagata tggtggagat gaatttttat
    21781 tccttttaca gaatacaagt tgtgtagaag cagaaaagat aatgattaat ataaattatg
    21841 aattatcaaa aataagtaat accgacgagt atccttatgc tctttccata agctatggat
    21901 tagttgagtg ggatggaata tccgatattg aaactttaat atcaaaggca gattctttga
    21961 tgtatgaaaa taagcttaaa aataaatcta ctttaaacta gctagttcag atattctaca
    22021 aaatatatat tataagatag tactaagaat gtcaaaatat atagattttg caaatattga
    22081 atacagttta ctaatgaatg cactggatgt aagtgttagt aaacacctat tagatgaaca
    22141 ctttactgtt gtttgggcta atgaccgtta ttatgaaatg ttcggctata cctagctaaa
    22201 aagttaaaaa tgaccactgt agccgaggga atagagacta gttttcaaaa agatttcttg
    22261 caagaaatag actgtgatat gttacaagga tacgtgttct ctagaccttt accaataaaa
    22321 gactttgaaa aacttatgtt tcaaaactcc tccaattaac aatataaaat tgcttattat
    22381 aagtgatatt attgtatcaa caaataaagg aattgtctca aaattgattt tttctaatca
    22441 aatttttatt ttgagacatt ctcatttttt tgcataagaa aatacccacc aagctacggt
    22501 ttttcttacc gctgttcggt gggtattagt agtattatga aatctgaaaa ctttaagtat
    22561 tactacttcc gctagcgcaa tcacaaaggt cgaaagcttc aaagcgaaaa taggcttttt
    22621 actcatcaaa cgtcaccgta cctgccaacc cgtccaccgt tatcatttgt ccgctcttaa
    22681 tagctcgtgt ggcaatgtgt gtagccataa cggctgggat gccatattca cgtgcgacaa
    22741 tgcttgaatg gctaagagga ccaccaatgt ccgttacaat cgcacttgca gatgaaaata
    22801 atggtgtcca tgctggagtt gtggtaactg caaccaaaac acttccaggt tgaaagcttt
    22861 caaaatctgc tggactattc agtacacaag ctggagccgt cacaacacca gtactggtac
    22921 caatgcccgt caacacaatt ttcccatctt tctgcttctg ttgtgcttgt gatatagttt
    22981 ttttgttttt ctctggcaac ttggatggtg acacataacc catgtatttt ttaagttcag
    23041 cttttcgaac aggtattatc ccgttcatat cagatagaga cttgttttta tccaactgct
    23101 ctataagtac ctccaattcc gattttgtga gccaataaat atcatctaaa tgtgaaatag
    23161 ctcctcctcg tatgaatcgt tctgagattt cctgaaacat acaacgaatc agaggatgtc
    23221 ccattcccat caaataaata gcattttcac gcataggaga ggtttcctgt gcccaatgga
    23281 gcaacttaaa aaatagtttt ttacgcaatc cacctatgtg ttgtaaaatc tcttcttctg
    23341 catgttttct acgcttttca aacgtggtct ggcgtaaaaa aggactttcc ccttttcctt
    23401 ccacaaatgt ttttacggat tcaaaagttg gtgtaagtgt ttcctgcggt gtggaatgcg
    23461 caaaatcaaa ctcataagcg gtacgaccaa actctttaaa gtacttattg attcgatttt
    23521 tccattctat ccatacttcc tgtgaaactc caacaggcac aactgaagac atgaaatctt
    23581 ctgctatctt tattgcagga ctgttttgca gataaaggtt gatgctgtta ttttgcttta
    23641 cccattctga aataccccac aactcctttt ccgattgcag aacaatcgta tcaaacccaa
    23701 gcaggaaaac ggaagtatcc gttataccag cacgtcgaac tgctccttga aataattttg
    23761 taaataatgt ttcactgata gaagcagcag gcaatgtaag ctgaatcctt gtgaaataaa
    23821 tacatgcggc ataaaatatt gtctgaatac cctccataat ttgatgggcg ttcatagtat
    23881 gcaggggctt ttcttcccat tgtttaatag catcctcata tccttttcgt gccgtttccc
    23941 agcgtgcaac gctgttcata agtgtcctac gtaaagagcg tggggaaagg gatttgatag
    24001 caatcaaaag tggatttgat ttagcagaaa gataaacata tccattaata accgtatatg
    24061 ccccgttttt tggtaataat tttttcgcac ttttaccaaa catatctatc cataaaagct
    24121 ctgatgcacg gtttacgatt tcaagaccaa gcgtggcgaa caaaggtgta acaggatttg
    24181 gcaaatgttc tgccaaactt ccctttgtgt atacaacatc ctgttctggc aatacccatt
    24241 ctggtggcag aacagtaatt ggacgagcct gaacaatgta caatttatct ttttccagtg
    24301 cccactctac atccataggc atttgataat acttctcaat tttctttcca agctgtatca
    24361 gttgcattac ctgattacga gtaagagcat atttttttct caacctttca ggaaccatgg
    24421 tttcttctgt tccttctgaa gtacgaaccg tcataatctc tttatttgcc acttcatacg
    24481 atataattcg ttcggagtcc ttatccacta cgattgtatc gggtgtaact aagctagaaa
    24541 ccaccgcttc accaagcccc catgcagcgt taataatcat ttcgctacgt ctaccattga
    24601 ttgggtttaa cgtaaacata ataccagatg aatcggaaaa tgcaagcttt tgtactacaa
    24661 cagcaagtgc gacaatctcg tgctttatat tattcttcac acgataagca atagcacgag
    24721 ctgtccataa ggaagcccag catctcttta cagagtcaat aactttatct tcaccttgta
    24781 tgttaagata agtttcctgc tgacctgcaa aagaagcgtc aggtaaatct tcagcagtcg
    24841 cagacgaacg gacagccacc gatatgttcc ctaatccagc ataagccatt ttaattgcgt
    24901 ccgacacttc ctgtggcatt tctccattat ggaaaagctc ccctattttc ttagatacat
    24961 cttcaagttg gctggtatta ttggaatcaa taccatctag cagtttatta attcgagact
    25021 gaatatggtt cgtctcaaca aaaatctggt atgaagcagt cgtaacatga aaaccgtctg
    25081 gcacagggat gcctgctgtc aatagttttg ataaagacat cccttttcca ccaacaattt
    25141 caatggttgc ttgtttatgt tccagtggca agacataata aatcataatc attcacctcc
    25201 atcattcata attccgtgca gaaatatatt cattgtttca tccaacattt tttccgaact
    25261 atccaatggt cgtgacgtgt agctgattga taacatggag ttaattaaca aacgtgtcac
    25321 aagagcggta tccgttttgc gaaagatgcc tgtggtcaca ccattatcaa ttaccgattt
    25381 tataatatct tgatatgcat aacgagcatc tttaagtctc tttcgatact cttcttctaa
    25441 ataatcagat tctgtattta accacatcag tacagttcta tactgctctg gaaatctaag
    25501 atgattaagc atgatttttc taaggcactg ttgtggtgaa ggttcaccat caataatcct
    25561 atgaacttgt tggatagttt tttctatttc tttctcaact gcatatacaa caatctcgtc
    25621 tttcgttttg aaaaaatcgt atagacttga ctttcccatg ttggctaaaa ctgcaatttc
    25681 tctcattgat gttttttgga atccattttc agccataaga ctcaaagcaa cagcaactat
    25741 tttttctcgg cgttctgctt gttgttcggg tgtaagcaca attccttttg gcatagggcg
    25801 atacctcctt ttagcgacca ctggtcgttt cttttttatt tatcatacag cgaccaacgg
    25861 tcacttgtca aggttaattt ttttcattgt atatggtact cgagataaaa atgttcattt
    25921 tagaaattgc tctatttaag tagaaatagg cttcatcatt agaaaacaag actataaatt
    25981 tgagatattt atcatgttca aatttcatca atatcaaagt ttaagatatt aataaaaaaa
    26041 gaattactaa gaaataacat ataaagattc aaaaaaggag ttgaacttaa aattcaatta
    26101 caaaaaatca aatttaagac aactccttta ttctttatct ctactattct ttatctctat
    26161 ttatttatta caactcccta acatttacca ctactgcctt aggtctagtc atagcctcga
    26221 ttgaatactt aacaccttga gttcccatac cagatgcctt tacacctaaa aatgggaagt
    26281 ggtctggacc tctttcagtc ttattattta tttgaacagt accaacttca agtttatcag
    26341 ctatataaaa tgccttatca atatcacttg taaatactga tgattgaagc ccatactctg
    26401 attgattagc aatttcaatt gcttgattta tatctttaac tcttataatt ggaagtactg
    26461 gaccaaatgg ttcttcccaa gcaattttca tatcaacatt tacattatct aacaatgttg
    26521 gatagaataa attatttttt ctaacattgc ctgttattaa ctttgctcct ttatgtaatg
    26581 catcatcaac caacccttga acaaaatcag ttgctttatt atctataaga ggagtgataa
    26641 ctacttcatc cattggattt ccaattgtca acttctctac caatggcttt atttttccga
    26701 ctaatttatc cgccacactc tcttgtacta aaattctctt tactgccgta catctttgtc
    26761 ctgaatatga atacgctcca gatactatat tcttagctgc aaaatctaag tctgcatctt
    26821 ctaatactat agccgcatct tttccaccaa gctccaataa taatggtacc attccagata
    26881 ttttagatat atgctgacca acttcagtac taccagtaaa gttaataaaa ttaattcctt
    26941 tatgcgttac aacataatct cctatctcac tacccctacc tgtaatagta ttaagtactc
    27001 catctggtat cccagctttt ctcataattt ctaccacatg aagtgcgcta atagcccctt
    27061 gtgtagcagg ttttaataca actgcatttc caccaataag tgctggagca atctttgaca
    27121 ttgataaatt tacaggataa ttaaaaggag atatagctaa aacagtacct aatggaaccc
    27181 ttgaaacata agacatctta tttcttgttc caccagggaa attatctcca ctaatggctt
    27241 caccctccat attttttccc acatcagctg tgtatcttaa aaaatctgct gttctctcaa
    27301 cttctgccct tgcagatttt atgtctttgg ctatttcaag taccagtata ttagctatct
    27361 catctatatt ttctaacaat aaatcagcag ccttatgaaa tatattggct ctcttatata
    27421 caggcatttc agcccatact tttatactct cttttgtgtt ttttataacc tcatctacct
    27481 catgttttgt catagattgt actttcccaa caagagaatt atctattggt gagtaaattt
    27541 ctattggctt tctcgaatta gattctaccc attttccatt tattaaattt ttatatacat
    27601 tttcttttgt tttaagttca ttaaacatat ttttattcct ctctctgata taactttgtg
    27661 tatttaaatt atagccattt attcgttatg taaacatttc tttttttcat aaacgtttac
    27721 ctataaaaaa attttaagtt aacgtttttc tacattcttc tattttaata acatactcgc
    27781 tccaaatcta tataggtcac actttaatat caatatacta atataccaat ataccaatat
    27841 accaatatac caatatacca atataaatat tataaacata aatcacttga caaatttata
    27901 agtagacaat attatatatc tatgacttaa aatattttta aagtcataga tatcatatat
    27961 agatagaaag gattgataaa aatggctaaa agttttacag aaatagaaaa agacaatata
    28021 agaaaaagac taatttcaga atgtgaaatc aactggtcta aatatggata caaaaaaact
    28081 aatattgatg aactttgttc aaaatcagga attgcaaagg gttcattcta cacattcttt
    28141 gattcaaaag aaaagttatt ttttgaagta ttaaatggaa tccaaaacag acttatatca
    28201 tcagtagatg aaattttaag taacatgcct ccaaaagaag gctttgcaaa agccttaaag
    28261 atgttgtatc gattatatga taaaaaccca ttcttatatt caccaaataa tactgattac
    28321 atcactttat tgaataagat acctaaagag atgctttcac aacttgaata cagcaatgta
    28381 caaagttttt atagcttaat tgaaagacat aatctcaagt taaaaataga gaaagaaaaa
    28441 gcctttggtg tttgcaatgc cctactgtca agcctattgc taaaagaaga tattggatat
    28501 gactacattg aagtatttga ttttatggta gacaatcttg tagaacacat acttgagtaa
    28561 taatttaaaa taaattttct aaacatttct ttataactag gaggagtaat atgattgaat
    28621 taatacaaag actaaatgat attatttaca aaataaatga taaactaaat atccacacaa
    28681 aacttgtaga ccctagcagt gagctcatgc cactttactc tatgttatct ataatcgttt
    28741 ctatatttct aataatatta ggtattaaag taagaaaaaa attccttata ataattgcta
    28801 ttatatcaat tattataaat attttaataa tcttagatag gtaggtacat atatggtaaa
    28861 atcctcgaac acttttaata aaaacttcaa cttgatgata ttaggtcaaa taatctcatt
    28921 gtttggtgca tcaatactta aatttgcttt atctttatac atacttgata taactggtaa
    28981 agcagaaata tttgctacta tactagcagt atcttcaatc ccaattatag tattctcccc
    29041 tattggtgga gctattgcag atatattcaa cagaagaaac ttaatggtta tttttgattt
    29101 ttcaagtagt cttacagtac taatcttagc agtattctta ttcaacaata atggttcaat
    29161 attacttgta ggaattatta tgaccatatt atcagtcata agcacaatgt atcaaccaac
    29221 tgttcagtca agtacacccc ttttagttga taatgagcat ttaatgaatg caaatggtat
    29281 tgtagctgga gttgcatctc ttacaaatat tgcaggacct gtattaggag gtgtcttgta
    29341 tggtgtgatt ggaattaatg caattatagt tataagttgt gtaagtttct ttctatctgc
    29401 aattatggag atatttatac agattccttt tatcaaacaa gagcaaaaca gcaacattat
    29461 aaaaactata tttactgata taaaggatgg tattgttcat atatgtaaag aaaatagatt
    29521 tatactaaaa atactttttt tagctatagc aataaactta tttttaagct ctatgttaat
    29581 agttggtatc ccctatatag taaaaatcac tatgggagct agtaacttct tatatggtct
    29641 agcagaagga gcaatttctt ttagttcact ggtagctgct gttagtattg gtattttctc
    29701 aaaacatcta aaaatcacta atttgcatat ttcctttatt atatgtgcag ttatgttcat
    29761 accaatggcg gtttcagtat atccatttat attaaacaca ggatttccag ttccattttt
    29821 aatctttata gtatcatcta tgctaatatt ttttacaacg actcttatct caatatatgt
    29881 tataacagtc acacaattaa aaactccaaa tgaactctta ggaaaagtaa tgtcaattct
    29941 ttttgcagga acagcaattg caatgcccct tggtcaggtt atgtatggta aactttttga
    30001 tttattatca gatagagtgt acatcattat actaggagtt ggatttatta cattacttat
    30061 agcatttgta tcaaagataa cattgaggaa cgaaaatctt tagatacaaa gaatttagat
    30121 ataaagattt aattttcact aatttctgaa tttaaatgca aaattgtgta tcagtatgtt
    30181 gacgttttag aaattgattg atataatcaa tggaaaataa actttataaa aattcaaaat
    30241 attcagctag aggagtgata aaaatgagtt acatgccaac tttagaacaa gcatgggaaa
    30301 tattaagaaa atacaataag gaagaatttc atataagaca tgctcaaatt gtatctggag
    30361 ttatgagata ctatgcaaag gagtacgacc ctgaaagagt agaattttgg gaaatagttg
    30421 gacttttaca tgatttagat tttgaaatgt atcctgatga acattgtgtt aaacaaagag
    30481 aattaatgac agagcttgat ttagataaat caataatcga ttctacaata agtcatggat
    30541 atggattaac tggttcagat gttaaaccag agcaatttat ggagaaagta ttatttgctg
    30601 tggatgaact tactggttta attggtgctg ctgcaataat gcgtccttca aagagcgttt
    30661 ctgatttaga attaaaatct gttaagaaga aatttaaaga taaatcattt gctgctggct
    30721 gttctcgaga cgttataaga agtggtgcag aaatgcttgg atgggaactt gataagctta
    30781 tccaaacaac tatagaagct atgagaagct tgattccaga gatggcaata tagctcctcc
    30841 atacatatac catagaagtt acatctttaa agagcatttc tctttttgat gcaacttctt
    30901 tttatatttt gtagaataaa aagtttaata ttttaaactc actatataat ctataataaa
    30961 tactataaat aatataatgt ataatagtca taaactttct aaccttaaaa gtttctaata
    31021 atcaataaac aattctaata tacaaatgt
//
LOCUS       DAMJVG010000047        29988 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.047, whole genome shotgun sequence.
ACCESSION   DAMJVG010000047 DAMJVG010000000
VERSION     DAMJVG010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 29988)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29988)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29988
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.047"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            69..1073
                     /locus_tag="PC512_002264"
     CDS             69..1073
                     /locus_tag="PC512_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HDF2442003.1"
                     /translation="MIIHKFIIHVLDKNSDTPILNDFEGRVSQDMDLFFQKKISKVSR
                     DNDIRTAVFNDYSNNLIKKCCEQIIYDESSFLNNSKEIAAYLFDVMKLNATLKSCDLA
                     ICLYSQKDEKKVAILKLDYNKSYTHSIEFKDDKFNIQMSKNEINIQETKTVKIAALVG
                     LSGMNDEYHLRVLDKDAEKEEANSKFITEFLNATKVKDDKYKTKMFKSTAENWITNAL
                     GNDIKQAEDVRSILNYTLKEKHEIDINNFVDKTIKDDKLKDSFKEHMEEKGLDKGFSI
                     DKKWVEKKLKKRNIKTDNGFDIKGNLTDFEDPMKYTVRQNQNGSIDIIIKNVKFYEEK
                     "
     gene            1082..1249
                     /locus_tag="PC512_002265"
     CDS             1082..1249
                     /locus_tag="PC512_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442004.1"
                     /translation="MTNKEMCKSKNLDEREIYKEFGKEICASCISDRVDCESKDCDIA
                     YENWLEKDAER"
     gene            1334..1606
                     /locus_tag="PC512_002266"
     CDS             1334..1606
                     /locus_tag="PC512_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442005.1"
                     /translation="MITTQMYKINNEIFLNDLCLEENKEMTIWVEKNKDTHEFIWLKI
                     ANVNGKLAIFIQDIENAVIKEWQGQIAYKKVIYQIEYEQVEKGEID"
     gene            1629..1859
                     /locus_tag="PC512_002267"
     CDS             1629..1859
                     /locus_tag="PC512_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019678173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3850 domain-containing protein"
                     /protein_id="HDF2442006.1"
                     /translation="MIHELKILPQYFKEVVNGNKNFEVRKNDRGFKKGDLLVLQEFDG
                     EKYTGLEIRKEIIYLLDNSNYLQDGYVVLGIK"
     gene            2013..2411
                     /locus_tag="PC512_002268"
     CDS             2013..2411
                     /locus_tag="PC512_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442007.1"
                     /translation="MQKDVWLYSWDNKYLSSDEYESKEEAIQAAKEELKEFGNFGESI
                     YVGKKEEVSIPNIDIEEALECIQKKIDDEVGECGEDWFENICVEDMIILSNRVNEVFE
                     KWIDEFGYKPYWFKLTDKEEIELNEVANES"
     gene            2401..2844
                     /locus_tag="PC512_002269"
     CDS             2401..2844
                     /locus_tag="PC512_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HDF2442008.1"
                     /translation="MKVNFTIDGEPKAKARPRMSTANGKAYTPDQTILYENWIRLMYN
                     STVKHFFEGNVKMTVICYFDITKKDREALQKNKVNTKAYKNAIDKVEGLIRPNKKPDL
                     DNIIKSVADSLNGIAYKDDSQIVEVVSKKYYSDRPRVEVELEDVS"
     gene            2867..3043
                     /locus_tag="PC512_002270"
     CDS             2867..3043
                     /locus_tag="PC512_002270"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442009.1"
                     /translation="MKKFIYINRHRVYIRNLFKISAIYKENHYIREFKSECLSNNTLN
                     AVIESSVRIGFGSK"
     gene            3148..3654
                     /locus_tag="PC512_002271"
     CDS             3148..3654
                     /locus_tag="PC512_002271"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442010.1"
                     /translation="MSKTKKEFFNATKKQLSNYKQLSTNIIKLKNEIQMLKDNSVGDL
                     MKGISYDSVKTGKTNKTSNMIEDAIVNVSDLITEKEIELYEAEIIKSTIDLAIRNLKP
                     IHRQIIELKYIDGLMWQEMVDIVHLEERQLSVRASQAISSISIALFGKKALIEQEPLF
                     ELLDYKLN"
     gene            4195..4872
                     /locus_tag="PC512_002272"
     CDS             4195..4872
                     /locus_tag="PC512_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bro-N domain-containing protein"
                     /protein_id="HDF2442011.1"
                     /translation="MLKILQEKNVKVMWSKNGEEVWFNANDVGEELGIVNIRDTLRNI
                     DREYKKKFNESTVGDSYTRNFKDKLPNFGTTFVTEEAVYNMSFRSNKPEAKLFTKWVT
                     KTLKQIRIHGYYIATEKDQEWLDIRTEGKKVRKDFTDEIQEFVYYATSQGSNKPQMYY
                     KHFTELVRKKLGIPKGVKRDELNQSELFDIQALERIISMKLPKLIDKDMNYKEVYKKI
                     KELIEMI"
     gene            4935..5636
                     /locus_tag="PC512_002273"
     CDS             4935..5636
                     /locus_tag="PC512_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442012.1"
                     /translation="MQDVKEKVKQDYIKGMKQKEISAKYDISLNTLKSWIKRYNWASE
                     KKKGAPKNKRGAPIGNKNATGPPGNKNAEKFGFFSKYLPEETRELIQEISIKDKFDIL
                     WEQITIQYAAIIRAQKIMYVKDKEEMIKELKKHESTENGEKIEYEFQFAWDRQASFLN
                     AQSRAMSELRSLIKQYDEMIHKDWNLATEEQKNRVEKLKCEVDNLKKSDTGDDSKIWV
                     EAIQNIAMKRGVNNG"
     gene            5629..7038
                     /locus_tag="PC512_002274"
     CDS             5629..7038
                     /locus_tag="PC512_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase B"
                     /protein_id="HDF2442013.1"
                     /translation="MDKALLTLLDCYWDNPVWFAEDMLNFKADKWQSDVLMALAQTPK
                     VSIRSGQGVGKTGLESIATVWYLSTRPFPKVVATAPTRQQLYDVLWAEIAKWLSNSKV
                     EKLLEWTKTKVYMKGFEERWWATARTAVKPENMQGFHEDYMLFVVDEASGVADPIMEA
                     ILGTLSGAENKLLLCGNPTRTSGTFYDSHNRDRDLYKTFKVSSLDSPRTSKDNIEMLK
                     RKYHEGSDPWRVRVLGEFPKGESDSLISLEAVETSTIREVNISNDYILNIGADIARYG
                     DDETIIAPRIGGKVFDLLTYSKKDTMETVGNILRAVDKFKNMYHQINRVKIKTDDDGL
                     GAGVTDRLKEVIRHERLKYEVIPIQNGSSAIEKDKYYNKASEMWDNMREELDANLSSF
                     IQNKEAIIQLPNDDKLIKQLSNRKYTVDSKGKIQIESKKEMKKRIGESPDRADAVIYS
                     FAENNNTDLSLLKGGSVWG"
     gene            7029..8531
                     /locus_tag="PC512_002275"
     CDS             7029..8531
                     /locus_tag="PC512_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDF2442014.1"
                     /translation="MGIISYVKKLFKRPAGEIMRMSSGNIGVYKLDDSRVDYELAREL
                     YQNKNANYKLGSSFVRPIVNSTTGFMGVPHFQIEDEEAQYILDEFVLDNTSKMLKTHT
                     DSLKQGDCYIWITREERENPLYPDKKVRLIYNFISPEEVKEIILDPTTKEPIAYILES
                     QNEWTDLGENKRKAKVKQIITAESRFVEVEGDKIEGLEEGETPNVWGFIPIIHFKNEA
                     DETLKYGQSDIEPIEPLLKAYHDVMLHALKGSKMHSTPKLKLKLTDVASFLAHNFGVE
                     DPVKFAKEGGKINLDGHEILFLNKDEEAEFVEVKSAIGDAKELLKLLFYCIVDVSETP
                     EFIFGVHTPSALASVKEQMPIMVNKIRRKREQFTNSWQLLARMVLIMSSNSSGMKYSS
                     YDVTIGWDEVNPRDDKELAETLEKVCSALDKALEGGFISEESTVNFLAQYIDTMSNYI
                     SDDPEIVGEREKIIKTKMLKYRLDDSQGLNDESNEIEKEINKIKDNNGNG"
     gene            8518..9531
                     /locus_tag="PC512_002276"
     CDS             8518..9531
                     /locus_tag="PC512_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442015.1"
                     /translation="MAMDKSTSELITVAGEYKKWALEARKKFIDLRLKQDDEIRTMYI
                     NITRNITKEIRKGNLSDFNKVRLKQILKQLTQEIKILNEQLVFNFDEYLNKNVETATS
                     YSKNILINAVETAQITKVTKTMIQKAFYDINIRTVEAYYTRVKDGLFLSDRIWSKCKK
                     YREDMKVILQTAVTEGQDCVKTAKMLDKYVLKGKKTLVDEYPNMIKRIGNRVPQNISY
                     EALRLARTEMTSAYGDGVLASAMINPATIGIQFMLSMAHPHTDICDEICGEDNFGLGK
                     GVYPINEAPVYPFHPHCLCIMLTVVQPLDILVGRLKNWIKNPMNDVPLEMWYQEVYGN
                     LNF"
     gene            9551..10885
                     /locus_tag="PC512_002277"
     CDS             9551..10885
                     /locus_tag="PC512_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442016.1"
                     /translation="MNVITGEMDSMNALISSIKPSDIPLAKDIDIEALKSIDDDPLEV
                     VVEIPATKSKRGWNYTAKSLKDIVDYTNENTLNGFLGHQKAENISTEFALPVTHWIGA
                     EMKGDKAYFRGLIDADATNLKRWIRTKRIKEVSIFGYPKLKKSAKGEMNVIGYEPLSI
                     DWTPLHRPGMPTSIVGMEMSPNGEQLDGTFEALRIDLREALKAKFSINDNNSYLYIQN
                     IRYDNNTVIYELEQNGLCKLYSIPFTIVENKINLGEEIEVIKKISYEAKGEMKGEENK
                     LEGKELIKNVKGLLQTGEISYSEVIQGIGLTKEIVTGEMEDVKSSLKAEKELREVKKV
                     LGIVGEMDTVEVAKKASKALENEKKEAWNCIVNKVIKDKVSGEIAQTLVKKMLNVEEG
                     SSEEVITGEIENILNDEFVKNTMSNMYKDNPTTTGLLNSSNNGSLTTKKNRI"
     gene            10901..11284
                     /locus_tag="PC512_002278"
     CDS             10901..11284
                     /locus_tag="PC512_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2190 family protein"
                     /protein_id="HDF2442017.1"
                     /translation="MAFKGQPTPSTITQITRAKISDGKSVRVILSEGESTKTQQFYLI
                     NGFFGVAMQDGEKGDEVTLQIEQAEYETDNIVTSEAFEAGKLIYWDNTAKKFTTTSAS
                     NRLVGRVTDGKDSNNVIWFILLPQQ"
     gene            11303..12340
                     /locus_tag="PC512_002279"
     CDS             11303..12340
                     /locus_tag="PC512_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate ammonia-lyase"
                     /protein_id="HDF2442018.1"
                     /translation="MAFKVISQENLLEQKRKETLQEDIPFIVNGEMEYVTKKISNGEM
                     ETLELNKPLGEMMTFSSTSNLKELLRKVVLDVELGREQVQLLYKPIYDSIADSNLPQV
                     MDAKWALQGNCVFLEHIEGEEIKFGTINAENGPVARIQTYATGFEYTKEMKDFNQTFS
                     VEILNKSIGESYNALLNHIHLSPIINFNYKASNKTAFKGETNDPIWLGIWRTLTQAQK
                     DTVIAKRQGNILMASSADQIEIEMALNGGHLLNGSMYPSIKNISTVIYYDGWEVTVGK
                     KTYSYKGVTPGKGYLIRPKRGFKELIKRDLTTEVGNADLSKLVENQIVGHCYRGAFAA
                     VEENVQEISFR"
     gene            12380..12718
                     /locus_tag="PC512_002280"
     CDS             12380..12718
                     /locus_tag="PC512_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442019.1"
                     /translation="MTPARDLIEKLRLLLNDKDKKSFTDEELNLFLEEADCIYCAASQ
                     GWILKSLQYENTVGEMYEYKVGQETYKSSSIKDLVSVAYQNADKFKDMCTNKKEKGSF
                     MLGISTEFEI"
     gene            12715..13092
                     /locus_tag="PC512_002281"
     CDS             12715..13092
                     /locus_tag="PC512_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442020.1"
                     /translation="MINIDRRRKDIIRTININPTNITITSIKKTEIDGAFEETETEIK
                     CVVRIFNEKTAEKQISSEKQGTFSSIRTYGMLVSNDVILEVNSRDSLEFECIYGRMKI
                     VNIYPQIVKGELCGYQCSLERID"
     gene            13094..13504
                     /locus_tag="PC512_002282"
     CDS             13094..13504
                     /locus_tag="PC512_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442021.1"
                     /translation="MSAFTNAINDINRKKAGMLVLCMSASAMLEGEAKANARWTDRTS
                     HARQSLNAKTLSGGNNFIIRLSHGAEYGGILEEGSKPHVITPKSAQALYWRGASHPVK
                     SVQHPGTKATPIIKPTIDKNIGKIGNMIFRYWSD"
     gene            13505..14326
                     /locus_tag="PC512_002283"
     CDS             13505..14326
                     /locus_tag="PC512_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442022.1"
                     /translation="MRAGIRKALIDNIKELKGCYEPNVPNKDTKKPYMVVVQGQDNDH
                     GETIGFERSIEVWIYEGRTTFKKLDKLTKQVVEVLDMNTIVDESENEAFTCIYKGTSE
                     NDIVVEEWDAIARGIRFSVIALEDKEDTTNDRWVEALSRHTKDLLEIESYKDNWKKNF
                     IAPCALWRTTHIENKRINYHLIEITKTMKCHVVSKNKDEIVKLLETLETSLIIDKRVR
                     LREDKNMYLTLVSVVEDRESDMFTTGQLTAVFKMIGKIKREGPTMDKIYGNGNLK"
     gene            14339..14542
                     /locus_tag="PC512_002284"
     CDS             14339..14542
                     /locus_tag="PC512_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442023.1"
                     /translation="MAETNNKKINVSKQEEKYLKSDFIKNSEALGYGKMVVAGALFNC
                     KKEELTKAEFEKLIKDFLEREVK"
     gene            14544..15965
                     /locus_tag="PC512_002285"
     CDS             14544..15965
                     /locus_tag="PC512_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath subtilisin-like
                     domain-containing protein"
                     /protein_id="HDF2442024.1"
                     /translation="MATGTWNEKERKEIPGFYNRFKTQAEKSTNTGLKGRLAMPIRAN
                     WGDVGKVVTIKNDLRQLKNLFGDDMNYSAFKLGKLALLGNVKELLLYRLVDGNQKKGT
                     LTLKDTTENSAKDVIKLETKYPTARNFNVTIKSNLVDSDKKDFIFFENTKQLFSSSIK
                     GTIDEIVLEINSNLDNEYVIATKVADSDTILANVVNQALEGGNDGCTSITNESYLKAL
                     EEFERYSFDSFVLDGVADEALQETTKAWVAKNKELGKDILLFLGGKTEDNIKQINDKS
                     KSFNDENIVNVGSSAYYENIKYTPSEVAVYIAALSVSKGITGSICNAKTIFEEVEPRL
                     SQSEVKECLKSGTLVLDFDDGDVIIVDDVNTFKKYVDDKNEAMGYISNIMFINTINKD
                     TSLKRKEFVGKIFNDATGQTTVICALKKYFEELMSQGIISEFNVDIDTELQATAKADE
                     FYWKWDAVKVDVMKKIYGTGYLG"
     gene            15981..16394
                     /locus_tag="PC512_002286"
     CDS             15981..16394
                     /locus_tag="PC512_002286"
                     /inference="COORDINATES: protein motif:HMM:NF020949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442025.1"
                     /translation="MYNDDYIEEASFLNGSDVVILIDGVEELYMEEIKADFEQDEQSI
                     KLLGCQNEISRVGTTKGSFSLNGYKTDSKFAKLGFRSFEIIYNLSNSETLGYESIRLK
                     NCRLKKLPLINSKAGEIVKIEVEGSFRGYDLLNEL"
     gene            16478..16969
                     /locus_tag="PC512_002287"
     CDS             16478..16969
                     /locus_tag="PC512_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442026.1"
                     /translation="MSEIYKRELENEVVEDNDLDEEIEETNEDRLKMKEDEIIAKLLE
                     DSPVPQRTVFLDRLGIPITLKALTEKEISKIRKECTKIVKVQGRREEKLNDDEFTLAL
                     IEKGTVKPNFSNQKLLNAMKVTNAREFIKRKFLAGELSKISDQILELSGFYDEISDDD
                     IKN"
     gene            16975..17127
                     /locus_tag="PC512_002288"
     CDS             16975..17127
                     /locus_tag="PC512_002288"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442027.1"
                     /translation="MGGRLTVLNNIFVKHHVPPDVYVKKNLMSQRLMKVFTQNEIEQE
                     NKAMKK"
     gene            17170..21420
                     /locus_tag="PC512_002289"
     CDS             17170..21420
                     /locus_tag="PC512_002289"
                     /inference="COORDINATES: protein motif:HMM:TIGR01760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HDF2442028.1"
                     /translation="MYHIDVVISAKGDGETKSKLSAMEKYMKQTEKRMQTLNRIKVNP
                     AIKATDKASSVVNRVNNNMNKAKKTVTARIKATDNASPVANRASNNVNKAKKTVTARL
                     KATDNASSTVNKVNNKIKEVAKPVPPVIIRGQDESSSIIDKVKAKIQNLKADTIIKIK
                     SQADEAINTISRTKNKLQEFVSKRYEAAVKIRDEASSALRGLTGKIDSFVSGAISKFA
                     RLATTAGALIGGIGVGSAVKGFATFEQSMKNTQAVSGATGKEMEALTAKARQLGRETS
                     FTAKDAGDAMYYMGMAGWKSEQMIKAIPDVLNLAAAGGTDLALTSDIVTDGLTALGMT
                     ANDTTEFVDVMAATITNSNTSVELMGETFKYVGSMGGALGVSMKDLSLATGLMASASV
                     KGSMAGTSLRGGLVRLIKPPEEAASAIKKYGIELKKNKNGSLDLAGTIGSLREKLGGL
                     KDVEKGVAISSIFGRTAMAGWAAVVNASESDFNKLTTAIAESEGEAKRIADMKLDTLS
                     GQFEILKSAIDDVRISVGQRLGPMTRGFVEDLIKKMPQIGDAIVGVVEKFVNNFDKIK
                     AGFQVLLPAIGSVIASVMVLKATFAFGGAIKSLSLLASTFGTAKLVAFGLTVGIGAIV
                     IAFAGMTVAISNNKTAMMDLQTRFGSFGEYVTTIMETVGGVIKLTLGNLLIMLGGIGK
                     GIGILLSDKSWDEKASSLKNLFGKTTAEIKTNTKEALSDINGETSNATALLKKSTSKE
                     LQGVTKAFSTAFDQSKNVTEKKSSDIARALTNGLKGLDDQSLTMMRGLNDNMAIILSG
                     VTADMKPSDKVNKITKNLDDAFKAGKLSAQEYRSSIQETLNFISKYSADSSNNLKQGM
                     SDAFNAFKEGTNIGGLKDGVTGMLNSLKATGPQALETLKGLGGKASEIFKGVDFNSSI
                     DAQKTKVLQNLNSLGLEGTQAIDTLRTIFSQASSALDTTNLKQGLSNTFNSFKEGFNS
                     GGIKNAINSMLGTINQAGPQMQQALGKMDGKMGQVFANVDFSTPIETQASKVLENLNN
                     LGIEGPKALETVRSIFAQASSQIQGSASQTAQQANQEVANALTQGNPAVQQAGQQLGT
                     DLTNGVVNGVQAGVPVVQQKSNELATATQNGVTNAVNSATPQIDNSNLTSGIDTAFNQ
                     ATATVQQGASSMYNGAKQSFTQLAQIGREAGSSLYNGATTSFNMLATNVRVACSSMYN
                     GARTSFTSLSSSAISAISAMCSSVVSQVSAMSSQIISYWNSVRATVSAPITASFNVKT
                     TQTTVKRTVNESSGGILGNILDRFADGGVATRTSICGENGAEMVIPLTNTRRSRAIEL
                     YEQTGKMLGLGSTPSQKVGNSNIVNNVRQFPLANVLDTDNKEYKEATPNSVNSSNNTI
                     NLGGISINVQNSDNKEEMIQELLSQVESGIREALQDIG"
     gene            21502..22245
                     /locus_tag="PC512_002290"
     CDS             21502..22245
                     /locus_tag="PC512_002290"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442029.1"
                     /translation="MWQKFKSMNGILKIIIGIIAIILLPITLVLLSIEFLVKAIGSKK
                     KAKIALGCILVFLTTLCTRNVYNVLSIEKEEHIPVKQVSYNDKDKGKSENNIQEQQQK
                     KEESKKLEEQKKNEEKEQNNEPTKFFTDVYLKNKNCVNMTSYEGIKSNLDIFGYKYEV
                     IEPNETTLRQINVYDNQSNDTIQFQFYENDTGEEVVTVMQYNKKDEPDKSVAISDGFH
                     TQPPKFQNHINNTNKEVNSIEEQINFMFN"
     gene            22314..22985
                     /locus_tag="PC512_002291"
     CDS             22314..22985
                     /locus_tag="PC512_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HDF2442030.1"
                     /translation="MVIDIYLKNEKEKIDFHFPVNPQDSLSIKKEKRFETVDIVNLGE
                     FDIKKEGEKIREISFKTFLPNLYDASYCRYSELKNPIEVVAMLEKWVDQAEPLRLIIT
                     GFGYNGLVTISSFSNTQTAGREEDRDIEITFRTYRELKIETLKKDTKSNTKTDLKDNR
                     PNTQTKSKIYTVKASDTLYKIAKNLLGKGSRWPEIYNIPENKKVIGKNPNIIKKGQKL
                     VIPSK"
     gene            22982..23944
                     /locus_tag="PC512_002292"
     CDS             22982..23944
                     /locus_tag="PC512_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdQ"
                     /protein_id="HDF2442031.1"
                     /translation="MKIILNGKYDIANFNEGITLSEAIDGVAYKMDVSLVEPKQLKDI
                     NIKKGDKIILIDIAYESKKEETIFDGVVWETRRSEKSKKLTLSCRERTVYMEESEEQY
                     QFKENTATQRIEYYCKQWNIPYYNLANTGKKLAKVIHKTNILDMIKKDLKETATKGGD
                     LFRVRMDNKLKLFKLGTNANVYKLDSILEDANFTSSFNDAVTSVKVLGKSKDENTKAP
                     IIGTYKKDADKFGTLQKIKQDEKIKNAKEAKKAAEAMFNSGEETISVDCAVDINRIRA
                     GDKVSLKSKEYYVIDVTHTLDSRPKMKLNIGSLEYIRRKFYNND"
     gene            23937..24302
                     /locus_tag="PC512_002293"
     CDS             23937..24302
                     /locus_tag="PC512_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442032.1"
                     /translation="MTDARFNGIARILKENMNKSVANGTFGMGCELAEITANGLKVNG
                     YKDEIQDYLVLENLTLKEDYFTFSDEALSGEYRHKHKIETPKELKPLRIGDNVLVAVM
                     GAEFVVIGRVVNAKPISSK"
     gene            24277..24735
                     /locus_tag="PC512_002294"
     CDS             24277..24735
                     /locus_tag="PC512_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HDF2442033.1"
                     /translation="MPNLFPQSETFETVELKNNDENELDLKGSFLFDFEKGEFVKNAD
                     GTLKKCDKVQAYKQWCQKAILTPRYKKAAYTNIYGSEIKDLIASNLSQSAKELEITRL
                     IKETILVHPYTKEVGEFSFNWLENSRLVEYEFDVLTIDDENIVIDGNIKR"
     gene            24744..25880
                     /locus_tag="PC512_002295"
     CDS             24744..25880
                     /locus_tag="PC512_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HDF2442034.1"
                     /translation="MERELPIPVFLTEDEDSVHERMLSNFQDVSTLEGDFIYDATRPT
                     AEQIAELKQLGLQNNLKIAFPQTSYGTYLEWLGECKGVFKNQPTKATGVITFTGVQGT
                     IITKGTIVTTIATDEKQSIEFELLETKTIGENETVDIKAESRIVGTIGNVSKGSISVL
                     LGSISGVKSITNKEDFRGGTDIEDEEHFRERVLVAEQEDKLSGASSDYIRWAKEVDGV
                     GYAYVVSEWAGAGTVKVLILDKNRKAATQELIDKVQEYIYPLNISEGENRDGKAPIGA
                     LVTVVTPDTLLINVKASFIFSNGFSEETVLNNLKTKIDKYLDKIDLGGTVSYNAIQAI
                     VGSMMLTDEGIEDFSNLTINDVKENIKLQDQVVGIGEIVNEVVG"
     gene            25877..26506
                     /locus_tag="PC512_002296"
     CDS             25877..26506
                     /locus_tag="PC512_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012705217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmfQ family protein"
                     /protein_id="HDF2442035.1"
                     /translation="MIASKKGKEMLLTLSPIYEQSIIMQSLYEAIGSEFDNLELLDEE
                     IELQLFPQSATWGLGFWENRVGLITNLDEDMETRRRKVIAKLQSKYIMTPKRMSMILQ
                     SYTGANIKINENISPYTFGVELTSTQGFPKDLEDLYKRVNVIKPSHLAVSYKLVSLLK
                     SKTYFAQTAIMSEEITIYPYTSKEVKASVKAKFALAHNMSSETLTVYPR"
     gene            26519..27625
                     /locus_tag="PC512_002297"
     CDS             26519..27625
                     /locus_tag="PC512_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDF2442036.1"
                     /translation="MADEQFYTILTNIGKAKIANAGMLGKPVVLEKIQAGDGGGNYYN
                     PTEEQTALKNKVWEGNINAFDNDENNPNWIIATACIPGSIGGFTVREMGLIDNEGDMI
                     AICKSPETYKPKIDNGAMKDLYLKFIIEVSNVEKVTLVVDPTAIFLTKKDEEKILTNI
                     NKLDTKIDTTKIELTSNIETAKTELNTRIDTENEKQNIKIDQLIAGGSNVASTQTITI
                     DDWVEDAESGFKATVTHGLLTQRIVVNIIDATTKENVVTNFKIIDDNSIEIRSEVKVE
                     LNVYVINGNAETHFINATVDDNRVSEMTTYSSKKIEDSISRIQLIDTSISITDANNRF
                     TSNKLDGVLEEIMVEISGQRTKGITIVNNLIDMI"
     gene            27639..28277
                     /locus_tag="PC512_002298"
     CDS             27639..28277
                     /locus_tag="PC512_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442037.1"
                     /translation="MTTKLTDNASLEELMTTLENVQADFQTGKNNISSALGSPFIGTD
                     KFGTTKTKIETLKNVLVETINSKNVSATSSETFTNLIEKVNWVFQSIEIFSLKNRIQA
                     TIVNTPSIVYNEVSSIKGTLRFTGELQSSKMRADYATAKIEILCGNRKEYFYVTDNTP
                     GASSSLVRFTKDIIVEKGMDIKVQILLTSVGAGNLDGSYAARAEIEELKILR"
     gene            28287..28499
                     /locus_tag="PC512_002299"
     CDS             28287..28499
                     /locus_tag="PC512_002299"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442038.1"
                     /translation="MKKQVYYNSLDEKEKIIDENSNLYIIEIYETLNENYLVLSSSPA
                     EDKELSYEELENELLIITNELQGGLL"
     gene            28499..28681
                     /locus_tag="PC512_002300"
     CDS             28499..28681
                     /locus_tag="PC512_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015981517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442039.1"
                     /translation="MNINNVVVRILAERILNKGLNPLKNREFELDDVTNTDYRTAVED
                     YIIKQSGVVEGAEPTK"
     gene            28781..28999
                     /locus_tag="PC512_002301"
     CDS             28781..28999
                     /locus_tag="PC512_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442040.1"
                     /translation="MKKIIVICILVLMLIIPTMGEIFIMVENIKLEGLEQNPTSCYIS
                     NPGIMGEAKCDAAYFIIAADFVNNLKVK"
     gene            29007..29498
                     /locus_tag="PC512_002302"
     CDS             29007..29498
                     /locus_tag="PC512_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HDF2442041.1"
                     /translation="MHLKDLDNSRSFLIQKLGGNMNLTIVFLATNIFIKLVILAIAFD
                     TLLGCLRAIKTHQFNSSFGINGGIRKVAMIACIFFLAVVDILTKFNFLFMLPQDWVDF
                     LRLNHLGISEFFSILFILYESVSILKNMYLCGLPVPKKLKDRIGNLLDTMTDELNVKG
                     GSK"
     gene            29498..>29988
                     /locus_tag="PC512_002303"
     CDS             29498..>29988
                     /locus_tag="PC512_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF2442042.1"
                     /translation="MKICITVGHSILKSGACTSADGVVNEYQYNKSLAPVLADRFKKE
                     GHKADVIICPEKQFKTKDEEKTYKIPRVNSGGYDLLIELHLNSSGVGAFGTELFYYSE
                     KGKEYAQRVVDKLSKPFIRKKGDKEVGNRGAKLDKSLYILNSSKPTAILIESFFCDNK
                     EDY"
BASE COUNT        12362 a         3271 c         5848 g         8507 t
ORIGIN      
        1 gaagttataa aaaatactat aagcgagaag attatagaac gctttaaaaa tttataaggg
       61 gtgaaattat gataatacac aaatttataa tacatgtttt agataagaac agcgatacac
      121 caatactaaa tgattttgaa ggtagagtta gtcaagatat ggacctattt tttcaaaaga
      181 aaataagcaa agtatcaaga gataatgaca tcagaacagc agtatttaat gactatagta
      241 acaatctaat taagaagtgt tgtgaacaaa ttatttatga tgaaagttca tttttaaata
      301 actctaaaga gattgcagct tatttatttg atgttatgaa attgaatgct acattaaaat
      361 cttgcgactt agcaatttgc ttatactctc aaaaagatga aaagaaagtt gctatattaa
      421 aacttgatta taacaagtca tatactcatt caatcgagtt taaagatgat aaatttaaca
      481 tacaaatgtc taaaaatgaa attaatatac aagagactaa gacagtaaaa attgctgctt
      541 tggttggttt gagtggaatg aatgacgaat atcatcttag ggttttagac aaggatgcag
      601 aaaaggaaga agctaattct aagtttatta cagagtttct aaatgctact aaagtgaaag
      661 atgacaagta caagactaag atgtttaaaa gtacagccga aaattggata actaatgctc
      721 ttggaaatga tataaaacag gcagaagatg taagaagtat attaaattat actttgaaag
      781 aaaagcatga aattgatata aataattttg ttgataaaac aattaaagat gataagttaa
      841 aagatagctt taaagaacat atggaagaaa aaggtcttga taaaggattt agtatagata
      901 aaaaatgggt tgagaaaaag cttaaaaaga gaaatataaa aactgacaat ggctttgata
      961 taaaaggtaa tctgactgat tttgaggacc caatgaaata tacagtaaga caaaatcaaa
     1021 atgggtctat agatataatt attaagaatg taaaatttta cgaagaaaag taggtgagca
     1081 tatgactaat aaagaaatgt gcaagtcaaa gaatcttgat gaaagagaaa tatataagga
     1141 atttgggaaa gagatttgtg ctagttgcat aagcgatagg gtagattgcg aaagtaaaga
     1201 ttgtgatata gcatatgaga attggctaga gaaggatgct gaaagataat tataaaaata
     1261 aagtcaaggt aagtttgtga atgaaactag aatgttatag acttactttg acttatagga
     1321 aggaggtgag attatgatta ctactcaaat gtataagata aataatgaga tatttctaaa
     1381 tgatttatgt ttagaagaaa ataaggaaat gaccatatgg gtagaaaaga ataaagatac
     1441 acatgaattt atatggttaa aaatagcaaa tgtaaatggc aagttagcta tatttataca
     1501 agatattgaa aatgcagtaa taaaagaatg gcaaggtcaa atagcatata aaaaagttat
     1561 atatcaaata gaatatgaac aagttgaaaa aggtgaaata gactaaaact tttaaagggt
     1621 gtgagcttat gatacatgaa ttaaaaatat tacctcaata ttttaaagaa gttgtaaatg
     1681 ggaacaaaaa ttttgaagtt aggaagaatg atagaggttt taaaaaaggc gacttgttgg
     1741 tgttgcagga atttgatgga gaaaaataca caggtcttga gatacgcaaa gaaattattt
     1801 atttacttga taatagcaat tatctgcaag atgggtatgt tgttttagga ataaaataaa
     1861 tgttttgtga ctaggaagtg agtttatgaa acgaagaaga tgcagttggt gtggcaagct
     1921 gttttatctt aaggaaaaat ctaaggagat ttattgttgt aaggactgta gaaagaaggc
     1981 taataagaaa aataaatagt ggaggtatta atatgcaaaa agatgtttgg ttatatagct
     2041 gggataacaa atatttaagt agtgatgagt atgaaagtaa agaagaagct atccaagcag
     2101 ctaaagaaga acttaaagag tttggaaatt ttggagaaag tatttatgtt ggtaaaaaag
     2161 aggaagttag tatacctaac atagatatag aagaagcatt agaatgtatt caaaaaaaga
     2221 ttgatgatga agttggagag tgtggggaag attggtttga aaatatatgt gttgaagata
     2281 tgataatact tagtaatagg gtaaacgaag tatttgaaaa atggatagat gaatttggat
     2341 ataaaccata ttggtttaag cttacagata aagaagaaat agaactaaat gaggtagcca
     2401 atgaaagtta attttacaat agatggagaa ccaaaggcga aagcacgtcc tagaatgagt
     2461 acagcaaatg gtaaggctta tacacctgac caaactatat tatatgaaaa ctggattaga
     2521 ctcatgtata actctacagt aaagcatttc tttgagggta atgtgaaaat gacagttatt
     2581 tgttactttg acattactaa aaaagataga gaagcactac agaaaaataa ggtaaatact
     2641 aaagcgtata agaatgctat agacaaggta gaagggttaa taagaccaaa taagaaaccc
     2701 gatttagaca atataattaa gtctgtagct gacagtttaa atggtatagc ttataaagat
     2761 gattctcaaa tagtagaagt agtgagtaag aaatattata gtgacagacc aagagttgag
     2821 gttgaactgg aagatgttag ttaaggagaa tattaaggtt aataatatga aaaaatttat
     2881 ttatataaat aggcatagag tatatataag aaatttattt aaaatatcag ctatatacaa
     2941 agaaaatcat tatattagag agtttaaaag tgaatgttta tctaataata ctttaaatgc
     3001 agtaatagaa tcttctgtaa gaataggatt tggtagtaag taaaaagaaa aaaaggagca
     3061 ttacttcacg ctcctacttg tcaaaaatat aaaactttta tatgcaaata ttattataac
     3121 ataaataatt gataggagtg tgtgagtatg tctaaaacta aaaaagagtt ttttaatgca
     3181 actaagaaac aactttctaa ttataaacaa ttaagtacaa atataataaa actaaaaaat
     3241 gaaatacaaa tgttgaaaga taattcggtt ggggatttaa tgaaagggat aagttatgat
     3301 agtgtcaaaa caggtaaaac aaacaaaact agcaatatga ttgaggatgc tattgttaat
     3361 gtatcagact taataacaga aaaagaaata gagttatatg aagcagaaat aattaaatct
     3421 acaatagatt tagccataag aaatttaaaa cctatacaca gacaaattat tgaacttaaa
     3481 tatatagatg gtctaatgtg gcaagaaatg gttgatatag tacatttaga agaaagacaa
     3541 ttaagtgtaa gagctagtca agctattagc tcaatatcaa tagcactgtt tgggaagaaa
     3601 gcattaatag agcaagaacc actttttgaa ttgttagatt acaaactaaa ttaaaaagta
     3661 agagtaattt tgagtgctga aaatgtgcag gtttttttgt tttagacatg agataatagt
     3721 attgtggaaa taaagatttc cctctcaaaa cttaatattt gactagggtt aagggattgc
     3781 cctagtcact acgaacagac taggcagggc gtgaggacgc tgttagttca attctaacta
     3841 tgttcaaaac ctattaatac actatatgta gtagttgaat taagattaaa atctcataca
     3901 attttgtatc ttaattcaga agtctaaaaa ccgagtgggg cttggtaacc tcactcacca
     3961 tgcaagtact ggtttaatct aggttcgatt cctggaactt gctcccttta ataatatgta
     4021 tcccccatta aaaaggctta gattaacttc taggtctttt ttaatacaaa aatttattaa
     4081 aaatgcacgg catgcactat tcagatatgc atgtcatgca tgtctaaagt cgaatattta
     4141 atattttcga tggctcaaat tgaggggtcg aaaataaaaa caggaggtag tagtatgttg
     4201 aaaattttac aagagaaaaa tgtaaaagta atgtggtcca aaaatggaga agaagtttgg
     4261 tttaatgcaa atgacgtagg agaggaacta ggcatagtaa atattcgtga tacattaaga
     4321 aatatagata gagaatataa aaagaaattt aatgagtcta ctgtcggaga ttcctacact
     4381 agaaacttta aagataaatt gcctaacttc ggtactactt ttgttacaga agaagctgtg
     4441 tacaatatgt catttagaag taataaacca gaagcaaagt tatttacaaa atgggttaca
     4501 aaaacactta aacaaattag aatacatggt tattatattg ctacagaaaa agaccaggaa
     4561 tggctggata taaggacaga aggcaaaaaa gtaagaaaag attttacaga tgaaatacaa
     4621 gagtttgtat attatgctac tagtcaaggt agcaataaac ctcagatgta ttataaacat
     4681 tttactgaac ttgtaagaaa aaaattaggt attccaaaag gtgtgaaaag agatgagtta
     4741 aatcaaagcg aactatttga tatacaagca cttgaaagaa ttatatctat gaaattacct
     4801 aagttaatag ataaagatat gaattataaa gaggtatata aaaagattaa ggaattaata
     4861 gaaatgattt aagggactgt cttgatggag ggtctttttt aattcccaaa acgacaaaca
     4921 aacgaggtgg tgatgtgcaa gatgtcaaag aaaaggtaaa acaagattac ataaaaggta
     4981 tgaaacaaaa ggaaatatca gcaaagtatg acattagttt aaacacttta aagtcatgga
     5041 taaaaagata caattgggct agtgagaaaa agaagggtgc acctaaaaat aaaagaggtg
     5101 cacccatagg taataaaaat gccactggtc ctcctggaaa taaaaatgct gaaaagtttg
     5161 gtttcttctc aaaatatcta cctgaagaaa ctagggaatt aatacaagaa atatctataa
     5221 aagataaatt tgatattctt tgggaacaga taacaattca atatgcagca ataataagag
     5281 cacaaaagat aatgtatgtt aaagacaagg aagaaatgat taaggagtta aagaaacatg
     5341 aaagcacaga aaatggtgag aagatagagt atgaatttca atttgcatgg gataggcaag
     5401 catcttttct taatgcacag agtagggcta tgagtgagtt aaggagttta attaaacagt
     5461 atgatgaaat gattcataag gattggaatt tagctacaga ggagcagaaa aatagagttg
     5521 aaaagttaaa atgtgaagtt gataacctaa agaaaagtga tactggagat gattcaaaaa
     5581 tttgggttga agctatacaa aatattgcaa tgaaacgtgg tgttaacaat ggataaagct
     5641 ttattgacac tattagattg ttattgggat aatcctgttt ggtttgcaga ggatatgtta
     5701 aattttaaag ctgacaagtg gcaatctgat gttctgatgg ctttagctca aaccccaaaa
     5761 gtatctatta gaagtggtca aggagtaggt aaaactggat tagaaagcat tgcaactgta
     5821 tggtatttaa gcactagacc ttttccgaaa gtagttgcta cagctccaac acgacaacaa
     5881 ttatatgacg tactatgggc tgaaatagct aaatggctaa gtaatagcaa ggttgagaag
     5941 ctacttgagt ggactaaaac aaaagtgtat atgaaaggct ttgaagaaag atggtgggct
     6001 acagctagaa cagcagtaaa gcccgagaat atgcaaggtt ttcatgaaga ttatatgtta
     6061 tttgttgttg atgaagcttc gggagttgct gaccccatta tggaagctat attgggaaca
     6121 ttatcaggtg cagaaaataa gcttctttta tgcggaaacc caactagaac gagtggaacg
     6181 ttttacgata gccataatag agacagagat ttatataaaa catttaaagt atcttcttta
     6241 gacagcccta gaacatcaaa agataatatt gaaatgctaa aaagaaagta ccatgaaggt
     6301 tctgaccctt ggcgtgtcag agtacttgga gagtttccaa aaggtgaaag tgattcttta
     6361 atatctttag aagctgttga aacaagcaca ataagagaag tgaatatatc taatgactat
     6421 atattaaata taggggcgga tatagcaaga tatggtgatg atgaaaccat aatagctcca
     6481 agaataggtg ggaaagtatt tgatttatta acttattcaa aaaaagatac aatggaaaca
     6541 gtaggaaata tattaagagc agttgataaa tttaaaaata tgtatcatca aattaacaga
     6601 gtaaaaataa aaacggatga tgatggctta ggtgcaggtg taacagatag attaaaagaa
     6661 gttataagac atgaaagact taaatatgaa gttataccta ttcaaaatgg ttctagtgct
     6721 atagaaaaag ataagtacta taataaagct tctgaaatgt gggataacat gagggaggaa
     6781 ttagatgcaa atttaagtag ttttatacaa aataaagaag ctataataca gcttcctaat
     6841 gatgataaac ttattaaaca actatcaaat agaaaatata cagtagattc aaaagggaaa
     6901 atacaaatag aaagtaaaaa ggaaatgaaa aaaagaattg gagaatcacc cgatagagct
     6961 gatgcagtaa tatattcgtt tgcagaaaat aacaatactg atttatcttt actgaaaggg
     7021 ggtagtgtat ggggataata tcttatgtaa aaaagctatt taaaagacct gcaggagaga
     7081 ttatgcgtat gtctagtgga aacattggcg tatataaatt agacgattct agagttgatt
     7141 atgagttagc aagagaactg tatcaaaata aaaatgctaa ttacaagtta ggttctagtt
     7201 ttgttagacc gattgtcaat tcaacaactg gttttatggg tgtacctcat tttcaaatag
     7261 aagatgaaga agctcaatat atattagatg aatttgtttt agataacaca tctaaaatgt
     7321 taaaaacaca tacagatagt ttaaagcaag gtgattgtta tatttggata actagagaag
     7381 aaagagaaaa tcctttatat cccgataaaa aagttagatt aatatataac ttcatatcac
     7441 ccgaagaagt gaaagaaata atattagacc ctacaacaaa agagcctata gcttatatat
     7501 tagaaagtca aaatgaatgg actgacttag gagaaaacaa gagaaaggct aaggtaaaac
     7561 aaataataac tgctgaaagt agatttgttg aggttgaagg tgataagata gaaggtttag
     7621 aagaagggga aacgcctaat gtatggggtt ttataccaat aatacatttt aaaaatgaag
     7681 ctgatgaaac attgaaatat gggcaaagtg atatagaacc aatagaacct cttttaaaag
     7741 cttatcatga tgttatgtta catgcgttaa aaggtagcaa aatgcactct actccaaaac
     7801 taaagttgaa attaactgat gttgcaagtt ttttagcaca caattttggt gttgaagacc
     7861 cagttaaatt tgccaaagaa ggtggaaaga taaatcttga tgggcatgaa atactattct
     7921 taaacaaaga tgaagaagct gagtttgtag aagtaaaatc agccataggt gatgctaagg
     7981 agcttttaaa gcttcttttt tattgcatag tagatgtatc tgaaacaccc gagtttatat
     8041 ttggagtaca tacacctagt gctttagctt ctgtaaaaga acaaatgcct attatggtaa
     8101 ataagataag aagaaaaaga gaacaattta caaatagctg gcaattactt gcaagaatgg
     8161 ttttaataat gagttctaat tctagtggta tgaaatattc atcttatgat gtgactatag
     8221 gttgggatga agtaaatcca cgagatgata aagaattagc tgaaacacta gaaaaagtat
     8281 gtagtgcatt agataaagct ttagagggtg gatttattag tgaagaatca acagtaaact
     8341 ttttagcaca gtatatagat acaatgagca attatataag tgatgaccct gaaatagttg
     8401 gagaaagaga aaagataata aaaaccaaga tgttaaaata cagattagat gactctcaag
     8461 gtttaaatga tgagtcaaat gaaattgaga aggaaataaa taaaataaag gataataatg
     8521 gcaatggata aaagtacttc ggaattaata actgttgcag gggagtacaa gaaatgggca
     8581 ttagaagcta gaaaaaaatt tatagattta aggctcaagc aagatgatga aataagaaca
     8641 atgtatatta acataacaag aaatattaca aaagaaataa gaaaaggaaa tctttcagac
     8701 tttaacaaag ttaggttaaa acagatacta aaacaattaa cacaagaaat aaaaatatta
     8761 aatgaacaac tagtatttaa ttttgatgaa tacttaaata aaaatgttga aacagctact
     8821 agttactcta aaaatatttt aattaatgca gttgagacag ctcaaataac taaagtaact
     8881 aaaactatga tacaaaaagc tttctatgat attaatataa gaactgtaga agcttattat
     8941 acaagggtta aggatggttt atttttatct gatagaattt ggtctaagtg taagaagtac
     9001 agagaagata tgaaagttat attacaaaca gcagtaacag aaggtcaaga ctgtgttaaa
     9061 acagctaaga tgttagacaa atatgtttta aaaggtaaga aaactttagt tgatgaatat
     9121 ccaaatatga taaaaagaat aggaaataga gtacctcaaa atataagtta tgaagcttta
     9181 agattggcaa gaactgaaat gacatcagct tatggtgatg gggttttagc ttctgcaatg
     9241 attaaccctg caaccatagg tattcagttt atgttgtcca tggcacatcc tcacacagat
     9301 atatgtgacg aaatatgtgg agaggataat tttggtttgg gtaaaggtgt ttatcctata
     9361 aatgaagctc ctgtatatcc attccaccct cattgtttgt gtattatgct tactgtagtt
     9421 caaccattag atatattagt tggaaggttg aaaaattgga ttaaaaatcc tatgaatgat
     9481 gtacctcttg aaatgtggta tcaagaggtg tatggaaatt tgaattttta aattgaaagg
     9541 tggtgattaa atgaatgtaa taactggaga aatggactca atgaatgcgt taatatctag
     9601 tataaaacct tctgatattc ctttagctaa agatatagac atagaagctt taaaatctat
     9661 agatgatgac cctcttgagg tagttgttga gataccagct acaaaatcta aaaggggatg
     9721 gaattatact gctaaaagct tgaaagatat tgtagattac actaatgaaa atactcttaa
     9781 tggcttttta ggacatcaaa aagctgaaaa tatatcaact gaatttgcac tacctgtaac
     9841 gcattggata ggtgcagaaa tgaaagggga taaagcttat ttcagagggc tgattgatgc
     9901 tgatgcaaca aatttaaaaa gatggattag aactaaaagg ataaaagaag ttagtatatt
     9961 tggttatcca aaacttaaaa agagtgctaa aggcgaaatg aatgttatag gatatgagcc
    10021 actatctatt gattggactc ctctacatag accaggtatg ccaacaagta ttgtaggtat
    10081 ggaaatgagt cctaatggcg aacagttaga tggaactttt gaagctttaa gaatagattt
    10141 aagagaagct ttaaaagcta agttttctat taatgataat aattcatatc tctatataca
    10201 aaacataaga tatgataaca atactgtcat atatgagttg gagcaaaatg gattatgcaa
    10261 gctttatagt ataccattta ctatagttga aaataaaata aatctaggtg aagaaattga
    10321 agtaataaag aaaataagct atgaagctaa aggagaaatg aaaggagagg aaaacaaatt
    10381 ggaaggaaaa gagttaataa aaaatgtcaa aggattactg caaactggtg aaatatcata
    10441 ttcagaggtc atacaaggaa taggcttaac taaggaaatt gtgacaggag agatggaaga
    10501 tgtaaaaagt tcattaaaag cagaaaaaga attaagagaa gtgaaaaaag tacttggaat
    10561 agtaggagag atggacacag ttgaagtggc aaaaaaggct tcaaaagctt tagaaaatga
    10621 gaaaaaggaa gcttggaact gtatagttaa taaagtaatt aaagataaag tgtcaggtga
    10681 aatagctcaa acattagtta agaaaatgtt aaatgttgag gaaggctcaa gtgaagaagt
    10741 aataacagga gaaatagaaa atatattaaa tgatgagttt gtaaaaaata caatgtctaa
    10801 tatgtataaa gataatccaa caacaacagg attattaaac tctagcaata atggaagttt
    10861 aacaactaag aaaaatagaa tataaaggag tgatgtttat atggcattta aaggtcaacc
    10921 aacgccaagc acaataacac agataacaag agcaaaaata agtgatggga aatctgtaag
    10981 agttattctt tcagaaggtg aaagcactaa aacacaacaa ttttatctta taaatggatt
    11041 ctttggagtc gctatgcaag acggagaaaa aggcgatgaa gttactttgc aaatagagca
    11101 agctgaatac gaaacggata atattgttac atcagaagct tttgaggcag ggaaattgat
    11161 ttattgggat aatacagcta agaaatttac tactacatct gcaagtaata ggctagttgg
    11221 tagagtaaca gatgggaaag acagtaataa tgtaatttgg tttatattat tacctcaaca
    11281 atagaaaagg agtgataaat atatggcatt taaagtaatt agtcaggaaa atttgctgga
    11341 acaaaaaaga aaagaaactt tacaagaaga tataccattt atagtaaatg gtgaaatgga
    11401 atatgtaaca aagaaaatat caaatggaga aatggaaacc ttggagttaa ataagccact
    11461 tggtgaaatg atgactttta gctcgacttc aaatttaaaa gagttattaa gaaaagttgt
    11521 attagatgtt gaactaggca gagagcaagt acaactatta tataaaccaa tctatgacag
    11581 tatagcagat tctaatttac cacaagttat ggatgctaag tgggctttac aaggtaactg
    11641 tgtattccta gagcatatag aaggtgaaga aattaaattc ggtacaataa atgcagaaaa
    11701 tggtccagtt gcaaggatac aaacttatgc aactggtttt gagtatacaa aagaaatgaa
    11761 ggattttaac caaacattta gtgttgaaat attaaataaa tcaattggtg agagttacaa
    11821 tgccttgtta aaccacatac atctaagccc aataataaat tttaattata aagcttctaa
    11881 taagacagct tttaaaggtg aaactaatga cccaatatgg ctaggaattt ggagaacatt
    11941 aacacaagca caaaaagata cagttatagc aaaaagacaa ggtaatatat taatggcttc
    12001 tagtgctgac caaattgaaa tagaaatggc gttaaatgga ggacatttat taaacggaag
    12061 catgtatcca tctataaaaa atatatcaac agtaatttat tatgatgggt gggaggttac
    12121 tgttggtaaa aaaacatatt cttacaaagg tgttacacca ggcaaaggat atttgataag
    12181 acctaagcga ggatttaaag agttaataaa gagagattta acaacagagg ttggaaatgc
    12241 tgatttaagt aagttagtag aaaatcaaat tgtaggtcat tgttatagag gtgcttttgc
    12301 agcagtagaa gaaaatgtac aagaaataag ttttagataa aacactcata agagtgttat
    12361 ttttatgagg tgataatata tgacaccagc tagagattta atagaaaaat taagactatt
    12421 attaaatgat aaagataaaa aatcatttac agatgaagaa ttaaacttgt ttttagagga
    12481 agcagactgt atttactgtg cagcttctca aggatggata ttaaaatctt tacaatatga
    12541 aaatacagta ggggaaatgt atgagtataa agtgggtcaa gaaacatata aaagctctag
    12601 tataaaagac ctagtatctg tagcttatca aaatgcagat aaatttaagg atatgtgtac
    12661 taacaaaaaa gaaaagggaa gttttatgtt aggaattagc acagaatttg aaatatgata
    12721 aatattgata gaagaagaaa agatataata agaactatta atataaaccc cactaatatt
    12781 actataacta gtattaaaaa aaccgaaata gatggagctt ttgaagaaac tgaaacagaa
    12841 ataaaatgtg ttgttagaat atttaacgaa aagacagcag agaagcaaat atcaagtgaa
    12901 aagcaaggta catttagttc tattagaaca tatggaatgt tagtaagtaa tgatgttatc
    12961 ttagaggtta acagtagaga ttctttagag tttgagtgca tatatgggag aatgaaaata
    13021 gttaatatat atcctcaaat tgtaaaagga gaactttgtg gatatcaatg ttcacttgaa
    13081 aggattgatt aaaatgagtg ctttcacaaa tgcaataaat gatataaata gaaaaaaagc
    13141 aggtatgctt gtactttgta tgagtgcaag tgcaatgcta gaaggtgaag ctaaagcaaa
    13201 tgcacgttgg acagatagaa catcacatgc aagacaaagt ttaaatgcta aaacacttag
    13261 tggaggaaat aattttatca ttagattatc tcatggtgca gaatatggag ggatacttga
    13321 agaaggctca aaaccacatg ttattactcc aaaatcagct caagccctat actggagagg
    13381 tgcttcacat cctgtaaaat cagttcaaca tcctggtaca aaagcaacgc ctattataaa
    13441 accaactatt gataaaaata taggtaaaat aggtaatatg atttttaggt attggagtga
    13501 ttaaatgagg gcaggaataa gaaaagcctt aatagataat ataaaagaat tgaaaggttg
    13561 ttatgaacct aatgtaccaa acaaagatac taaaaaacct tatatggtag ttgtacaagg
    13621 gcaagacaat gaccatggag aaacaatagg ttttgaaaga agtatagaag tatggattta
    13681 tgaaggtaga acaacattca agaaattaga taaattaact aaacaagttg ttgaagtctt
    13741 agatatgaat actatagttg atgaatctga aaacgaagct tttacttgca tttataaagg
    13801 tacaagtgaa aatgatattg ttgttgagga atgggatgct atagcaagag gtataaggtt
    13861 tagtgtaata gctttagaag ataaagaaga tacaactaat gataggtggg tagaagctct
    13921 atctaggcac acaaaggatt tattagaaat agagagttat aaagataatt ggaagaaaaa
    13981 ctttatagct ccatgtgcat tatggcgaac tacacatatt gaaaataaaa gaattaacta
    14041 tcatttaatt gagattacta aaactatgaa atgtcatgtt gtaagtaaaa ataaagatga
    14101 aatagttaag cttcttgaaa cattagaaac aagcttaata atagataaaa gagtaagact
    14161 tagagaagat aagaatatgt atttaactct tgttagcgta gttgaggata gggaatcaga
    14221 tatgtttaca actggacaat taacagctgt gtttaaaatg ataggaaaga taaaaagaga
    14281 aggtcctact atggataaaa tttatggtaa tggaaattta aaataggagg tgcaagaatt
    14341 ggctgaaaca aataataaaa agattaatgt aagtaagcaa gaagaaaaat atttgaaaag
    14401 tgattttata aaaaatagcg aagcacttgg ctacggaaaa atggtagttg caggtgcttt
    14461 atttaattgt aagaaagaag aacttacaaa agcagaattt gagaaattaa taaaagattt
    14521 cttagaaaga gaggtgaaat aaaatggcaa ctggtacatg gaatgaaaaa gaaagaaaag
    14581 agatacctgg tttttataac aggttcaaga ctcaagcaga aaaatctaca aacacaggat
    14641 taaagggtag attagcaatg cctattaggg ctaattgggg agacgttggc aaggttgtaa
    14701 caataaaaaa tgatttaaga cagcttaaaa atctatttgg ggatgatatg aattattcag
    14761 ctttcaagct aggcaaattg gctctgttag ggaatgtaaa agagttatta ctatatagac
    14821 ttgtagatgg aaatcaaaag aagggtacat taacactaaa agatactaca gaaaatagtg
    14881 caaaagatgt aattaagtta gaaactaagt atccaacagc tagaaacttt aatgtaacaa
    14941 taaaatccaa tttagtagat tcagataaaa aggactttat attctttgaa aatactaaac
    15001 agttatttag ttcaagtatt aaaggcacta tagatgaaat agtactagaa ataaactcaa
    15061 atttagataa tgagtatgta attgcaacta aagtagctga tagcgataca attctagcaa
    15121 atgtagtaaa tcaagcttta gagggtggga atgatggttg cacatctatt actaatgagt
    15181 cttatctaaa agcactagaa gaatttgaaa gatatagttt tgactctttt gtacttgatg
    15241 gtgtggctga tgaagcattg caggaaacta caaaagcttg ggtagctaaa aataaagaat
    15301 taggaaaaga tatactactt tttctaggtg gaaaaacaga ggataatata aaacagataa
    15361 atgataaatc aaaaagtttc aatgatgaaa atatagttaa cgttggaagc tcagcttatt
    15421 atgaaaatat aaaatataca cctagtgaag tagctgttta cattgctgct ctttctgtaa
    15481 gtaaaggtat aacgggtagt atatgtaatg caaaaactat atttgaagaa gtagaaccac
    15541 gattaagtca atcagaagtt aaagagtgtt tgaaaagtgg tacattggtc ttagattttg
    15601 atgatggaga tgtgattata gttgatgatg tgaacacatt taaaaaatat gtagatgata
    15661 aaaacgaagc aatgggatat atctctaata tcatgtttat taatactata aataaagata
    15721 cttcattaaa aagaaaagag tttgtaggta agatatttaa tgatgcaaca ggtcaaacaa
    15781 ctgttatatg tgcattgaag aaatattttg aagaattgat gagtcaaggt attatatcag
    15841 aatttaatgt tgatatagat acagagcttc aagcaactgc caaagcagat gaattttact
    15901 ggaagtggga tgctgttaag gttgatgtca tgaaaaaaat atatggtact ggatacttag
    15961 gataaaggag gttatagatt atgtataatg atgattatat agaagaagcc agttttctga
    16021 atggttctga tgtagttata cttattgatg gtgtagaaga gctatacatg gaagaaataa
    16081 aagctgattt tgagcaagat gagcaaagta ttaaactgtt agggtgtcaa aatgaaatat
    16141 caagggttgg tactactaaa ggttcattct ccttgaatgg atataagaca gattcaaaat
    16201 ttgcaaaatt aggatttagg tcttttgaaa taatatataa tttatctaat tctgaaacat
    16261 taggatatga aagtattaga ttaaagaatt gtagattaaa aaaattgcct cttataaatt
    16321 ctaaagctgg tgaaattgta aaaatagaag tagagggaag ttttagagga tatgatttgt
    16381 taaatgaact ttaaaacaaa ataatgttgt actttaaagc tatgaacaat taattttgtt
    16441 tgtagctttt taaaattaaa aatattggag gaatagtatg tcagagatat ataaaagaga
    16501 gttagaaaat gaagtagtag aagataatga tttagatgaa gaaatagaag aaacaaatga
    16561 agatagattg aagatgaaag aggatgaaat aatagcaaag ctattggagg attcaccagt
    16621 tcctcagaga actgtgtttt tagatagatt aggaatacca attactttga aagcattaac
    16681 agaaaaagag attagtaaaa taagaaaaga atgcactaaa attgtaaagg tccaagggcg
    16741 aagagaagaa aaattaaatg atgatgagtt tactctagca ttaatagaaa aaggaactgt
    16801 aaaacctaat ttttctaatc aaaaattact taatgctatg aaagtaacaa atgctagaga
    16861 atttataaag agaaaattct tagctggaga attaagtaaa ataagtgacc aaatattaga
    16921 attatccggt ttttatgatg aaataagtga tgatgatata aaaaactaat aaaaatgggg
    16981 ggacgactga ctgttttaaa taacatcttt gtcaagcatc atgttccccc agatgtttat
    17041 gttaagaaaa atttaatgtc tcaacgctta atgaaagtat ttactcaaaa tgaaatagag
    17101 caagagaata aagctatgaa aaaataaata tctacagaaa ggtaggtgag ggaaatagct
    17161 aaaaaggaaa tgtatcatat tgatgttgtc ataagtgcaa aaggcgacgg agaaacaaaa
    17221 agcaaactaa gtgctatgga aaaatacatg aagcagacag aaaaaaggat gcaaacactt
    17281 aataggataa aggttaatcc tgctataaaa gctactgata aagcttcaag tgttgtaaat
    17341 agagttaata acaatatgaa taaagcaaaa aaaactgtta cagctagaat aaaagctaca
    17401 gataacgcga gtccagtagc caatagagct agcaataatg ttaataaagc taaaaagaca
    17461 gtaacagcaa ggttgaaagc tacagataat gcgagttcta ctgttaacaa agttaataat
    17521 aagataaaag aagttgctaa gcctgtacct cctgtaatca tacgaggaca agatgaatct
    17581 agttctataa tagataaagt aaaagctaag attcagaatc taaaagctga tactatcata
    17641 aaaataaaat cacaagctga tgaagctata aatactattt ctcgaactaa aaataaatta
    17701 caagaatttg tgagtaagag atatgaagca gcagttaaga ttagagatga agctagttca
    17761 gcacttagag ggcttacagg aaaaatagat tcttttgtaa gtggagctat tagtaaattc
    17821 gctagactgg ctactaccgc aggagcttta ataggtggaa ttggtgtagg ttctgctgta
    17881 aaaggatttg ctacttttga acaaagtatg aagaatacac aagccgtaag tggagcaaca
    17941 ggaaaagaaa tggaagcttt aactgcaaaa gctagacagc ttgggagaga aactagtttt
    18001 acagctaaag atgcaggaga cgcaatgtat tacatgggta tggcaggatg gaagtccgag
    18061 caaatgataa aagcaattcc tgacgttctt aacttggcag cagcaggagg aacagactta
    18121 gcgttaacga gtgacattgt gactgatgga ctaactgcat taggaatgac tgcaaatgac
    18181 acaactgaat ttgttgatgt gatggcagca acaataacta attcaaatac aagtgttgag
    18241 ttaatgggtg aaacatttaa atacgtaggc tctatgggcg gagcattagg agtatctatg
    18301 aaagatttat ctcttgcgac aggtctaatg gctagtgcaa gtgtcaaggg aagtatggca
    18361 ggtacttcgt taagaggagg tctagttaga ttaataaagc caccagaaga agccgcatct
    18421 gcaattaaaa aatatggaat agaattaaag aaaaataaaa atggaagttt agacttggca
    18481 ggaacaatag gaagtcttag agagaaatta ggaggattaa aagatgttga aaaaggtgtt
    18541 gcaatatcct ctatatttgg tcgtactgca atggcaggtt gggcggctgt agtaaatgct
    18601 agtgaaagtg actttaataa gttaactaca gctattgcag aaagtgaagg agaagctaag
    18661 agaattgctg atatgaagtt agatacctta tcaggacaat ttgaaatttt aaaaagtgct
    18721 attgatgatg taaggataag tgtaggtcaa agactaggac ctatgacaag aggatttgta
    18781 gaagatttaa ttaagaaaat gccacaaatc ggtgatgcta tagttggagt agtagaaaag
    18841 tttgttaata atttcgataa aataaaagca ggatttcaag tattattgcc tgcaattggt
    18901 tccgttatag cctctgttat ggtacttaaa gccacatttg cttttggagg agccattaaa
    18961 agtttaagtt tacttgcaag tacttttggt acggctaaat tagttgcctt cggattaaca
    19021 gttggaatag gggctattgt tatagctttt gcaggaatga ctgttgctat ttctaataat
    19081 aaaactgcta tgatggactt acaaacacgt tttggttcgt ttggtgagta tgttactaca
    19141 ataatggaga ctgttggtgg agtcataaag cttacgttag gtaacttgct tataatgtta
    19201 ggtggaattg gaaaaggaat aggaatactt ttatctgata agagctggga tgaaaaagct
    19261 tcatcactta aaaatctatt tggcaaaaca acagcagaaa ttaaaacaaa tacaaaagaa
    19321 gctttatcag atataaatgg agaaacttct aatgcaacag ctctattaaa aaagtctact
    19381 tcaaaagagt tacaaggtgt tactaaagct ttctcaacag catttgacca atctaaaaat
    19441 gtaacagaga agaaatctag cgatatagct agagcattaa caaatggatt aaagggttta
    19501 gatgaccaat ctcttactat gatgagaggt ttgaatgaca atatggcgat aattttatct
    19561 ggtgtgacag cagatatgaa acctagtgac aaagttaata aaatcaccaa aaatcttgat
    19621 gatgctttca aagcaggtaa attaagtgca caagaataca gaagtagcat acaagagact
    19681 ttaaatttta taagcaagta tagtgcagat tcttcaaata atttgaaaca aggtatgagt
    19741 gatgctttca atgccttcaa ggaagggaca aatataggcg gattaaaaga cggagtaaca
    19801 ggaatgttga actctttaaa agcaactggt ccacaagctt tagaaacctt aaaaggttta
    19861 ggaggaaaag caagtgagat tttcaaagga gtggatttta attcttctat agatgcacag
    19921 aaaactaaag tattacagaa tttaaatagt ttaggattag aaggaacaca ggctatagat
    19981 actttaagaa ctattttctc acaagcatca tctgctttgg atactacaaa tttaaagcaa
    20041 ggtttaagca atacatttaa ctcttttaaa gaaggattta atagtggagg aataaaaaac
    20101 gctataaata gtatgcttgg aactattaac caagcaggtc cacaaatgca acaagcatta
    20161 ggcaaaatgg atggaaagat ggggcaagta tttgctaatg tagactttag tactccaata
    20221 gaaacacaag ctagtaaagt tcttgaaaat ttgaataatc taggaataga aggaccaaaa
    20281 gctttagaaa ctgtaagaag tatatttgct caagcttcaa gtcaaataca aggttcagct
    20341 tctcaaacgg cacaacaagc gaatcaagaa gtggctaatg ctctaactca aggtaatcca
    20401 gctgtacaac aagcaggaca acaattaggt acagatttga ctaatggtgt agtaaatgga
    20461 gtacaggcag gagtgccagt tgtacagcaa aaaagtaatg aacttgctac agcaacacaa
    20521 aacggagtaa caaatgctgt aaatagtgca actcctcaaa tagataattc aaatcttaca
    20581 agtggtatag atacagcatt caatcaagct actgcaacag ttcagcaagg ggcgagtagt
    20641 atgtataatg gtgctaaaca aagttttaca caactagcac aaataggtag agaagcaggt
    20701 tcaagtcttt ataatggtgc tacaacttct tttaatatgt tagcaacaaa tgttagagtt
    20761 gcatgtagta gcatgtacaa tggagctaga acatctttta cgagtttaag cagttcagct
    20821 ataagtgcca tttctgctat gtgtagttct gtagtaagcc aagttagtgc catgtcgagt
    20881 caaattatca gctattggaa tagtgtaaga gcaacagttt cagcaccaat tacagcatct
    20941 tttaatgtta agactactca aacaacagtt aaaagaaccg taaatgaaag tagtggtgga
    21001 atactgggta atatactaga ccgttttgct gatggtggag tagcaacaag aacttctatc
    21061 tgcggagaga atggagctga aatggttatc cctcttacaa acactagaag aagtagagca
    21121 atagaattat atgaacaaac aggtaaaatg ttaggattag gttcaactcc ttctcaaaaa
    21181 gtaggtaatt ctaatattgt aaataatgtt agacaatttc ctcttgcaaa tgttttagat
    21241 acagataata aagaatataa agaagctaca ccaaacagtg ttaattcttc taataatact
    21301 ataaatttag gcggaatatc tataaatgtt caaaatagtg ataacaaaga agaaatgata
    21361 caagaactat tatctcaagt agaaagtgga ataagagaag cattacaaga tattggataa
    21421 tgtcgaattg ttgctaaaaa aatcttcctc ataaatgata taatattgtt aaaatatgca
    21481 aatttatgag ggggaaattt tatgtggcag aaatttaaaa gtatgaatgg aattttaaaa
    21541 attattattg gaattatagc tataattctt ttaccaataa cattggtttt gttatctatt
    21601 gagtttttag ttaaagctat tggaagtaag aaaaaagcta aaattgcatt aggttgcata
    21661 ttagtttttt tgacaacact ttgtactaga aatgtttata atgtactaag tatagagaaa
    21721 gaagagcata ttcctgtgaa gcaagtttct tataatgata aagataaggg aaaatccgag
    21781 aataatattc aagaacaaca acaaaagaaa gaagaatcaa aaaaattgga agaacaaaaa
    21841 aagaatgaag aaaaagagca aaacaatgaa ccaacaaagt tttttactga tgtatattta
    21901 aaaaataaaa attgtgttaa tatgacatct tatgaaggta taaagtcaaa cctagatata
    21961 ttcggttata aatatgaagt tatagagccg aatgaaacta cattaagaca gattaatgta
    22021 tatgataacc aaagtaatga taccattcaa tttcaatttt atgaaaatga tactggagaa
    22081 gaagttgtaa cagttatgca atacaataaa aaagatgaac ccgacaaatc tgttgcaata
    22141 agtgatggtt tccatacaca accaccaaaa tttcagaatc atattaataa tacaaataag
    22201 gaagttaata gcatagaaga acaaataaat tttatgttta attaatattt gtataatact
    22261 ttaaagctct tacagtttgt aggagctttt tattgtaaaa aagaggtgat aacttggtaa
    22321 tagatattta tctaaaaaat gaaaaagaaa aaatagattt tcattttcca gtaaatccac
    22381 aagattcttt atctataaaa aaagaaaaaa ggtttgaaac tgtagatata gtaaacttag
    22441 gtgaatttga tataaaaaaa gaaggggaga agataagaga aatatcattt aaaacatttc
    22501 tgcctaactt atatgacgct tcttattgca gatacagcga gttaaaaaat ccaatcgaag
    22561 tagtggcaat gcttgaaaaa tgggtagacc aagccgaacc tttaagactt attataactg
    22621 gttttggcta caatggatta gtcacaatat ctagttttag caatactcaa acagcaggaa
    22681 gagaagaaga tagagacatt gagataacat ttagaactta cagagaactg aagatagaga
    22741 cattaaaaaa agatacaaaa agtaatacta aaacagattt aaaagataat agacctaata
    22801 cccaaactaa atctaaaata tatactgtta aagcaagtga tacattatat aagatagcta
    22861 aaaatctttt aggtaagggt tcaaggtggc cagagattta taatataccc gaaaacaaaa
    22921 aagtcattgg taaaaatcct aatataatta aaaaaggaca aaagttggtg ataccttcta
    22981 aatgaaaata atattaaatg gaaaatatga tattgcaaat tttaacgagg gaataacatt
    23041 aagtgaagct atagacggag ttgcatataa gatggatgta tcattagtag aacctaaaca
    23101 acttaaagat ataaatatta aaaaaggtga taaaataatt ctaattgata tagcatatga
    23161 gagtaaaaaa gaagagacaa tatttgatgg agttgtatgg gaaactagaa ggagtgaaaa
    23221 gagtaagaaa ctaacattgt cttgcagaga aagaacagtt tacatggaag aatcagagga
    23281 acaatatcag tttaaagaaa atacagcaac acagagaatt gaatattact gtaagcaatg
    23341 gaatataccc tattacaact tagctaatac agggaagaaa cttgctaaag taatacataa
    23401 gacaaatata ctagatatga taaaaaagga cttaaaagaa acagcaacaa aaggtggaga
    23461 cttatttaga gtaaggatgg ataataaatt aaaattattc aagcttggta ctaatgcaaa
    23521 tgtatataaa ttagatagta tattagaaga tgctaacttt acaagtagtt ttaatgatgc
    23581 agtaacaagt gtaaaagttt taggtaagag taaagacgaa aatacaaaag cgcctataat
    23641 tgggacatat aaaaaagatg ctgataagtt tggaacacta caaaagatta aacaagatga
    23701 aaagataaaa aatgctaaag aagctaagaa agcagcagaa gcaatgttca atagtggaga
    23761 ggaaacaata agtgtagatt gtgcagtaga tataaataga ataagagcag gtgacaaagt
    23821 aagtttaaaa agtaaagaat attatgttat agatgtcact catacactag attctagacc
    23881 gaaaatgaag ctgaatatag ggtctttaga atatataagg aggaaatttt ataataatga
    23941 ctgatgctag atttaatgga attgctagaa tattgaaaga aaatatgaat aaaagtgtag
    24001 caaatggcac ttttggaatg ggttgtgaac ttgcagaaat aacagcaaat ggattaaaag
    24061 taaatggcta taaagatgaa atacaggact atctagtatt agagaattta acattaaaag
    24121 aagattattt tactttttca gatgaagctt taagtggaga atatagacat aagcataaaa
    24181 tagaaactcc aaaggaattg aagccactac gtataggcga taatgtgcta gtagctgtta
    24241 tgggagctga atttgtagta attgggaggg ttgtaaatgc caaacctatt tcctcaaagt
    24301 gaaacttttg aaactgtaga attaaaaaat aatgatgaaa atgaattgga cctaaagggt
    24361 tcttttttat ttgattttga aaaaggtgaa tttgttaaaa acgcagatgg aacactaaaa
    24421 aaatgtgata aggtgcaggc gtacaaacaa tggtgtcaaa aggctatatt aacacctaga
    24481 tacaaaaaag cagcttatac aaacatttat ggaagtgaaa taaaagactt aatagctagt
    24541 aacttatctc aaagtgcaaa agagcttgaa ataactagat taataaaaga aactattttg
    24601 gttcatcctt acacaaaaga agtaggagag tttagcttta attggttgga gaatagcagg
    24661 ttagtagagt atgaatttga tgtactaaca atagatgatg aaaatatagt aattgatggc
    24721 aatataaaaa ggtaggtgat tatatggaaa gagagctacc tataccagta tttttaacag
    24781 aagatgagga ctctgtacat gaaaggatgt taagcaactt tcaagatgtt tctacattag
    24841 aaggtgactt catctatgat gcaacaagac ctacagcaga gcagatagct gaattaaaac
    24901 aactaggatt acaaaataat ttaaagatag catttcctca gacttcttat ggaacttatt
    24961 tagagtggct tggtgaatgt aaaggagtat ttaaaaatca accaactaag gctactggag
    25021 ttattacatt tacaggtgta caaggaacta tcattacaaa aggaactata gtaactacta
    25081 ttgcaactga tgaaaaacag agcatagaat ttgagcttct tgaaaccaaa actataggag
    25141 aaaatgaaac agtagatatt aaagcagaaa gtaggattgt aggaactata gggaatgtgt
    25201 ctaaaggtag tatatccgtt ttactaggtt ctattagtgg tgttaaatca attactaata
    25261 aagaagattt cagaggtgga acagatatag aagatgaaga acattttaga gaaagagttc
    25321 ttgtagcaga gcaagaagat aaacttagtg gagctagttc agattatatt cgttgggcta
    25381 aagaagttga tggagttgga tatgcttatg tagtttcaga atgggctgga gcagggacag
    25441 taaaagtatt aatactagat aaaaacagaa aagcagcaac acaagaatta atagataagg
    25501 tccaagaata tatatatcca ttgaatatat cagaaggaga aaatagagat gggaaagctc
    25561 ctatcggtgc attagttaca gttgtgacac ctgacacatt acttattaat gtaaaagcta
    25621 gttttatatt tagtaatggc tttagtgaag aaactgtatt aaacaatcta aaaactaaga
    25681 tagataaata tttagataag attgatttag gggggacagt ctcatacaat gctatacagg
    25741 cgatagtagg ctctatgatg ctgacagatg aaggtataga agacttttct aatcttacta
    25801 taaatgatgt aaaagaaaat ataaaattgc aagaccaagt ggtcggaata ggggaaatag
    25861 ttaacgaggt ggttggatga tagcttctaa aaaaggtaaa gaaatgcttc ttacattatc
    25921 tcctatttat gaacaatcta tcataatgca aagcttatat gaagctatag gaagcgaatt
    25981 tgataatcta gagttattgg atgaagaaat agaattacaa ttattccctc agagtgcaac
    26041 atggggtttg ggcttttggg aaaatagagt agggttgatt actaacttag atgaagatat
    26101 ggaaactaga agaagaaaag taattgctaa acttcaaagt aaatatatca tgacgcctaa
    26161 aagaatgtct atgatactcc aatcttatac aggtgcaaac ataaaaataa atgaaaatat
    26221 atctccatat acttttggtg ttgaattaac cagtacccaa ggttttccta aagatttaga
    26281 agatttatat aagagagtaa atgttataaa accttctcat ttagctgtaa gttataagtt
    26341 agtttcttta ttgaaaagta aaacctattt tgcacaaaca gcaattatga gcgaagaaat
    26401 aactatatat ccgtacacaa gcaaagaagt aaaagcaagt gttaaagcca agtttgcact
    26461 agctcataac atgagttcag aaacattaac agtgtatcca agataggagg tggtataaat
    26521 ggctgatgaa caattttaca cgatactaac aaatataggt aaagctaaga ttgctaatgc
    26581 aggaatgtta ggtaagccag tagttttaga gaagattcaa gcaggagatg gtggaggaaa
    26641 ttattataat ccaacagaag aacaaacagc attaaaaaat aaagtttggg aagggaatat
    26701 aaatgctttt gataatgatg aaaataatcc taactggatt attgcaacag catgtatccc
    26761 tggttcgata ggcggattta cagttagaga aatgggtctt atagataatg aaggagatat
    26821 gattgcaatt tgcaaaagcc ccgaaactta caagccaaaa attgataatg gagctatgaa
    26881 agatttgtat ttgaaattta tcatagaagt atctaatgta gagaaagtga cattagttgt
    26941 tgaccctaca gctatttttc taactaaaaa agatgaagaa aaaatattaa caaatattaa
    27001 taaactagac actaaaatag atacaaccaa aatagaatta acaagcaaca tagaaactgc
    27061 taaaacagag ttaaatacta gaattgacac agaaaatgag aaacaaaata ttaaaattga
    27121 ccaattaatc gcaggtggtt caaatgtggc atctacccaa acgataacaa ttgatgattg
    27181 ggtggaggat gcagaaagtg gattcaaagc aactgtaaca catggtttgt taacacagag
    27241 aatagttgta aatattatag atgctactac aaaagaaaat gtagttacaa actttaaaat
    27301 tatagatgat aattctatag aaattagaag tgaggtaaaa gttgaattaa atgtctatgt
    27361 gataaatgga aatgcagaaa ctcattttat taatgcaact gtggatgata acagagtgtc
    27421 tgaaatgact acttattcgt ctaagaaaat agaggattct attagccgta tacagcttat
    27481 agataccagt ataagtatta cagatgctaa taatagattt acaagtaata agttagatgg
    27541 ggtattagaa gaaataatgg tagaaataag tggccaaagg actaaaggaa ttactatagt
    27601 aaataattta atagatatga tataagcgag gtgaaaatat gacaacaaag ttaactgata
    27661 atgctagttt agaggaactt atgactacat tagaaaatgt acaagctgat tttcaaactg
    27721 gtaaaaataa tatatctagt gcattgggta gtccttttat tggaacagat aaatttggta
    27781 caactaaaac aaaaatagaa acattaaaaa atgtattagt ggagacaatt aattctaaaa
    27841 atgtttcagc aacatcatct gaaacattta ctaatttgat tgaaaaagtt aactgggttt
    27901 ttcaatcaat agaaattttt tctttaaaaa atagaattca ggctacaatt gtaaacactc
    27961 ctagcatcgt ttacaatgaa gtatctagta taaaaggtac attaagattc acaggcgaac
    28021 ttcaatcgtc taaaatgcgt gctgattatg caacagcaaa aatagagata ctatgtggaa
    28081 accgaaaaga atacttttat gttactgaca atactcctgg tgcatcttct tctcttgtaa
    28141 gatttacaaa agatattatt gttgagaagg gcatggatat aaaagtacaa atattattaa
    28201 catctgtagg agcaggaaat ttagatggtt catatgcagc tcgtgcagaa atagaagaat
    28261 taaaaatatt aaggtaggaa taaattatga aaaaacaagt atattataat tctttagatg
    28321 aaaaagaaaa aataattgat gaaaactcta atttatatat tatagaaata tatgaaactt
    28381 taaatgaaaa ttatttagta ttatcaagta gtccagcaga agacaaagaa cttagttatg
    28441 aagaattaga aaatgaatta ttaattataa ctaatgaatt acagggagga ttgttgtaat
    28501 gaatataaac aatgttgtag taagaatatt agcagagaga atattaaata aagggttaaa
    28561 tcctttaaaa aatcgagaat ttgagttaga tgatgtaact aacacagact ataggacagc
    28621 agtagaggat tatataatta aacagagtgg agtagtagaa ggagcagaac caacaaagta
    28681 ggttcttttt ttatataaat taaaaataat ttcctttttt agttatatat tttttattct
    28741 tatctataat aaaaaaattc tattaaaagg agattgaaaa atgaagaaaa taattgtaat
    28801 ttgcattcta gttctaatgt taattatacc tactatgggg gagatattta taatggtaga
    28861 aaatataaag ctagaggggc tagaacaaaa cccaacaagt tgttacattt ctaatccagg
    28921 gattatggga gaagcaaaat gtgatgcagc atactttatt atagctgcag atttcgttaa
    28981 caatttaaag gtaaaataat aaattaatac atttaaagga cttagataat tctaggtcct
    29041 ttttaataca aaaattagga ggaaatatga atttaacaat agttttttta gcaacaaata
    29101 tatttataaa attagtaata ttagcaatag catttgatac actgttaggt tgcttaagag
    29161 caataaaaac acatcagttt aactcaagtt ttggaataaa tggtggaata agaaaagtcg
    29221 caatgatagc atgtatattt tttctagcag tagttgacat tcttacaaag tttaactttt
    29281 tatttatgtt accacaagat tgggttgatt tcttacgact aaatcatctt ggaatatctg
    29341 aatttttctc tattttattt attctatatg aaagtgtaag tatattaaaa aacatgtatt
    29401 tgtgtgggtt accagtgcct aaaaaattaa aagatagaat aggtaactta ttagatacta
    29461 tgacagatga attaaatgtt aaaggaggta gtaaataatg aaaatatgta taacagtagg
    29521 acacagtatt ttaaaaagcg gagcatgtac ttctgctgat ggagtagtta acgagtatca
    29581 atacaataaa tctcttgccc cagtgttagc agatagattt aaaaaagaag gtcataaggc
    29641 agatgtaata atatgcccag aaaagcagtt caaaactaag gacgaggaaa agacttataa
    29701 aatacctaga gttaatagtg gaggatatga cttacttata gagttgcatt taaattcaag
    29761 tggtgtagga gcttttggaa cagaattatt ttactatagt gaaaaaggga aggaatatgc
    29821 gcagagggtg gtagataaac tgtctaaacc tttcataaga aaaaaaggag ataaagaagt
    29881 aggtaataga ggtgctaaat tagataaaag tttatatatt ttaaatagtt ctaaacctac
    29941 tgcaatacta attgaaagtt tcttctgtga taataaagaa gattatga
//
LOCUS       DAMJVG010000048        28140 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.048, whole genome shotgun sequence.
ACCESSION   DAMJVG010000048 DAMJVG010000000
VERSION     DAMJVG010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 28140)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28140)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28140
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.048"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            58..822
                     /locus_tag="PC512_002304"
     CDS             58..822
                     /locus_tag="PC512_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDF2442043.1"
                     /translation="MFAEERIQAILNILKKEGRVTVKELSSKFNVTEDCIRKDLKNIE
                     KISSIRRIYGGAVLARETLENQDTKDRKEINIPTKKIIAEKAFNLIEDRETIFLDIST
                     INILLAKLLAESNKKVTLVTNMLDILNVVTSKPNNLNIISTGGLLNLSLDGFVGTPTI
                     EFISKYKFDKTFMGSCGVDVFNSSLTTFEIEDGLTKKAIINSSKKVFIVMEDKKFKFD
                     GNFKFAHLEDISSIITEKTPTPDIVDILSEFNVNVL"
     gene            complement(1111..1332)
                     /locus_tag="PC512_002305"
     CDS             complement(1111..1332)
                     /locus_tag="PC512_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442044.1"
                     /translation="MDRLKRDMKNMKEDLKEGVKKTAYVMKNTAEDLKDDAQGAMVNL
                     EMKKDEMMERYEQKKFSKELEKQMKNEMK"
     gene            complement(1733..3010)
                     /locus_tag="PC512_002306"
     CDS             complement(1733..3010)
                     /locus_tag="PC512_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HDF2442045.1"
                     /translation="MRRIFDKWEKLSIKYKLFSITTSLLIALALIIYLILYFLLPSYY
                     HEYKIESLQESLKSLVDSSIHFDTYTLEERLYYMAKDQNLAILLKDNQGKIVYGKNEV
                     VILRYSKYMINSLEDEYRTSIPIYTKDAKDGPYTLELVMPLQPIDEANEVIRKLMPYI
                     ISIAILIAIIGAYIYSIVITKPLINIIESEREQEYRRKDFVATISHELKTPITIISGQ
                     IEGMIYSVGKYKDRDTYLKKSYECTQELKDLVNEMIEVSKSEILEKDLKLVSINISEL
                     LNRLVKRQVFLIEEKHMKTILKIEENLEIKADQERITKAINNIINNAIKYSPEESELI
                     IRLYDKNKRISKKTSNQRVVLEIENTGVTIEKRYLEEIFNPFYRIEKSRSRKTGGSGL
                     GLYIVSQIFKSHGFDYSIKNKENSVVFTVEFKN"
     gene            complement(2994..3662)
                     /locus_tag="PC512_002307"
     CDS             complement(2994..3662)
                     /locus_tag="PC512_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2442046.1"
                     /translation="MNSSILVIEDDSNIQELISEFLSAEGYQVDTANDGLEGIQKFKQ
                     GSYDLVILDIMMPNLDGYGVCKMIRKSSSVPIIFLTALNDEGDQLKGFDLECDDYITK
                     PFSFNLLIKRVEAILRRSNKTINDKFIVFEKLKLDLNTYIAEIDGEPIELTLKEFNIL
                     KALIEKYPQVITREGLLDSIWGYDYYGDTRIVDAHIKNIRKKISLPYIKTVKGIGYTL
                     EKDI"
     gene            complement(3822..6323)
                     /locus_tag="PC512_002308"
     CDS             complement(3822..6323)
                     /locus_tag="PC512_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HDF2442047.1"
                     /translation="MSSNKVVESYKITGMTCAACAKAVERVTKKMDGVYDQNVNIATE
                     KLKIEYDNSKVNFDDIKQVVEKAGYGIIKEESNKKIDMKIDGMTCAACAKAVERVVKK
                     LDGVESISVNIATDKANIDYDPSKVKLSQIKAAIEKAGYKPIEEVRNKVDVDEDKLRK
                     EREMKSLFVKFIVAIVFAVPLFYIAMGPMIIKPIGPWPLPEIINPMTNTFNYALIQLI
                     LVIPVMIAGYKFYINGFKSLFSLSPNMDSLVAIGTLAAFLYSLYTTLQIANGQIQGMH
                     HHQLYYESAGIIIALILLGKYLESKSKGKTSEAIKKLMGLQPKTAIVLVDGKEVETPI
                     EEVEIGDILLVKPGTKIPVDGVVIEGYTSVDESMLTGESIPVEKNVGSKVTGASINKN
                     GVIKFKAEKIGGDTALAQIIKLVEDAQGTKAPIAKLADTVSGYFVPIVIAIAVVASLL
                     WFLIGGKDIVFVLTIFISVLVIACPCALGLATPTAIMVGTGKGAENGILIKGGEALES
                     AHKVNTVIFDKTGTITEGKPKVTDIVLNNNVKEEYLIKIASSAEKGSEHPLGEAIVKY
                     GEEKNIKFEKVDNFKAIPGAGIQVTINDESILLGNRKLMNDNNIKLGDLEEKSNILAS
                     QGKTPMYIAVDGNLSGIIAVADVVKESSKKAIEILHDMGIKVAMVTGDNAKTANAIAN
                     QVGIDMVLAEVLPEDKSKEVEKLQNQGKFVAMVGDGINDAPALAKADIGIAIGSGTDV
                     AIESADIVLMKSDLIDVPTAIKLSHETIKNIKQNLFWAFGYNTIGIPVAAGILYVFGG
                     PLLNPMIAAAAMSLSSVSVVSNALRLKNFKAYKRD"
     gene            complement(6614..6805)
                     /locus_tag="PC512_002309"
     CDS             complement(6614..6805)
                     /locus_tag="PC512_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1450 domain-containing protein"
                     /protein_id="HDF2442048.1"
                     /translation="MIRVCPNCSNVDVNKLKTLVGEENVKTGCIGQCRAFKKEAVGII
                     DNELEIKETEAEFFEACKE"
     gene            complement(6953..7195)
                     /locus_tag="PC512_002310"
     CDS             complement(6953..7195)
                     /locus_tag="PC512_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442049.1"
                     /translation="MLEVTKIIIKYFASESDTFVKEEVCNFEELLKWSHKFIEGKKIE
                     DVLYIKSKENYKVNVIKSLEIKELEIVRKQQIPPYM"
     gene            7407..9230
                     /gene="typA"
                     /locus_tag="PC512_002311"
     CDS             7407..9230
                     /gene="typA"
                     /locus_tag="PC512_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HDF2442050.1"
                     /translation="MSQKHKIINIAVIAHVDAGKSTLVDAFLSQSGVFRKNEVVKDCV
                     MDSNDLEKERGITIYSKNCAINYEDYKINIVDTPGHSDFSSEVERVMKTVDTVILLVD
                     ASEGPMPQTRFVLQKSLEFGLKPILFINKIDKKDQRAEEVVNEVFDLFVDLNATDEQC
                     EFPIIYGIAKQGIAKLEMDDDSEDLSPLFKTIVNHVEAYPNYDNEPLQFQISALAYDD
                     YVGRLGIGRIYKGTLKNNTQVAICREDSVVSKGKVSKLSVYEGLKQVEVDEATSGEIV
                     VIAGIPDISIGETICDLDSPLPMEMIKIEEPTLSMNFLVNDSPFVGKSGKFVTTRHLK
                     DRLEKELEVNVGLKVEPLDTTDGYKVSGRGELHLSILLENMRREGYEVGVSKPEVLMH
                     KEDGKLMEPIERVVVNCPEVYSGTIINELNMRKGMMESMSIEGDYVKIEFLAPTRGLL
                     GYRSEFINATRGEGTLVRSFEKFEEFKGEIPSRGNGVLIAQGPGVTMGYSLNALSDRA
                     VMFVDPGVEVYEGMIIGMNSRKDDMVVNPCKNKKMSNVRASGSDDAIKLSPPRIFTLE
                     EALEFIEDDELVEITPDSIRLRKRFLNEHDRLRYNKSRQGK"
     gene            complement(9320..10228)
                     /gene="trxB"
                     /locus_tag="PC512_002312"
     CDS             complement(9320..10228)
                     /gene="trxB"
                     /locus_tag="PC512_002312"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HDF2442051.1"
                     /translation="MVDIIVIGAGPAGLTSAIYAMRAGLSVTVFEKNIYGGQVASTSE
                     VENYPAVQKISGVEFSNNIYNQAVAQGVDIQFDEVEEINLEGKVKVVKTSSGEHKAKA
                     VILANGVERRKLGCAGEQEFTGRGVSYCATCDGAFFKDKEVAIVGGGNTALEDALFLA
                     NNCTKVYLIHRRDSFRGEEVLEKSVKARENIEILYSHGVEKIEGEKTVSKIEVKNLKT
                     EEKRTIDVSGIFIAIGLKPNNKMFENVLDLDEGGYIISDESCTTSVEGVYVAGDSRTK
                     FLRQIITAASDGAIAAVQAANYINVE"
     misc_binding    11030..11261
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            11369..12850
                     /locus_tag="PC512_002313"
     CDS             11369..12850
                     /locus_tag="PC512_002313"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HDF2442052.1"
                     /translation="MYYSSTRGTEEKVTASQAIIKGISNDGGLYVPSEFPNVKNELIN
                     LVNLTYSQIAFFVLSKFLCDFTEDEIKNCIENAYDEKFDCSSIAPLNKVNDTYFLELY
                     HGPTLAFKDMALTIMPHLLKTSIKKDNLEKDVVILTATSGDTGKAALEGFKDIDKIKI
                     IVFFPEDGVSPVQKLQMKTQTGKNTYVVGIKGNFDDAQSGVKKIFSDKEFNQKLLDNN
                     YILSSANSINIGRLLPQVAYYFYSYMKLVSNSDINLNDKINFVVPTGNFGNILAGYYA
                     KQMGLPINKLICASNDNNVLYDFFKTGVYDKNRTLKLTTSPSMDILISSNLERLLFEI
                     SNRNTDIVNKLLSDLSDKGVYKISDDMEKNLASFYGEYSNEEEVKSTINNVFKNYNYL
                     IDTHTAVAYNCYEKYKKETSDNTKTVIVSTASPFKFSEDVLKSIDCDFKDLDDFAIID
                     RLSSISKIDIPKPIKNLKNAEILHKDIYEKDELKLAIKKFLKV"
     gene            12860..13753
                     /locus_tag="PC512_002314"
     CDS             12860..13753
                     /locus_tag="PC512_002314"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HDF2442053.1"
                     /translation="MLEIIVPATSANIGPGFDCLGIALNIYNKFYVEEIESGLEIEGC
                     EDAYKNENNLVYTSMKYFFDRVKPEKIPAGIKIKIQSEVPICRGLGSSASCIVAGVIA
                     ANALSGANLDKNQLLNIASEIEGHPDNVAPAILGNMIVSVTDNENIHYDIIKIPEELK
                     FCAMIPNFKLSTEKARGVLPKEIPYSDGVFNVSRVALLISALLNKNFDLLKVACQDKL
                     HQDYRGTLIENYNDIVEKSEQLNSIGVFLSGAGPTIMSLIKENDDSFVDNMKNYLQKL
                     KSDWEIKELCCDSNGAVLNII"
     gene            13877..14938
                     /locus_tag="PC512_002315"
     CDS             13877..14938
                     /locus_tag="PC512_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015617764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitronate monooxygenase"
                     /protein_id="HDF2442054.1"
                     /translation="MIIKELIIRDLVAKVPIIQGGMGVGISRSSLAGAVAKLGGVGVI
                     SGVQIGYDEEDFETNTINANLRAIKKHISKAKEISNGGIIGINFMVAMKEYETYVKEA
                     VKAGVDLIISGAGLPNKLPSLVKGSNVKIAPIVSTAKAANVILKMWDRKEKTTADLIV
                     VEGPKAGGHLGYSNEELDNIDSIDYDKEFVEILKVANTYGEKFGRNIPVVAAGGITSS
                     SDVKKYIDMGASGVQVGTRFVATYECDAHENFKMAYINASEEDVHIVKSPVGLPGRAI
                     RNKFIEEVKINRPEIKKCYNCLIPCNPKETPYCISQALINAVKGDVENSLLFCGNDAY
                     KIDKLSTVEDVINELISEL"
     gene            complement(15093..15605)
                     /locus_tag="PC512_002316"
     CDS             complement(15093..15605)
                     /locus_tag="PC512_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HDF2442055.1"
                     /translation="MSDFKEILAEEIKNNPFGLIGKDWTLITAENEGKVNTMTASWGG
                     LGVMWGKDVAFVVIRPQRYTKEFIDNTDKFSLTFFDEDFRKELSYCGKVSGREEDKIS
                     QIGFNIEHLNDTPYFKEAKMAIICKKMYSQKLEPQCFIAEGIDGRWYPQKDYHTLYIA
                     EITNVLVKED"
     gene            16125..17060
                     /locus_tag="PC512_002317"
     CDS             16125..17060
                     /locus_tag="PC512_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HDF2442056.1"
                     /translation="MIRYYKTIDSKLEKLSFFEDGCWINLVEPNHSEINEISNLLNID
                     VESIESALDEEERSRIDVEDNHTLILIDIPVDESDSNSSHYTTIPLGIILTEEAIVTV
                     CDAQTKILNDFIVGHIKDFFTFKKTRFLLQILHKNAAYYLHYLRKINKMTIIIEREIY
                     KSMKNKELVQLLELEKSLVYFSTSLKSNELVLNKMVRTAGIKKYPDDEDLLEDVIVEN
                     RQALDMAKIYGDILSRIMDAFSAIISNNQNNVMQILTVVTLIFSIPTIISGFFGMNVI
                     NMPFSNNPNGFWIILLITSIICIVITFFMSRNKLL"
     gene            complement(17152..19023)
                     /locus_tag="PC512_002318"
     CDS             complement(17152..19023)
                     /locus_tag="PC512_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sel1 repeat family protein"
                     /protein_id="HDF2442057.1"
                     /translation="MKNTKFSIKKIKNISNDPKVVHTKGALLEKMGKMESAIELYKSA
                     ALDNYVKSQYTLGNIYESKKQFKEAEKWYSMAYKSGSEDAAFDLGNMYYKLDGYEYAI
                     YWYEKIANLGYLQAQNNLGVCHFKMKDFVRCEKWLKTAADKNLGKACFNLGVLYTFLE
                     KDDEAYEYYKKGSVLLDDDAKYNLAILNGKKKDNKSTVSLYKQLYKSGHMKGCFNLGM
                     IMEINDNLEDAEKYYKKSADRDDVKSEYRLAYVYDRKEELGDAIYYYEKAIEKNHTLS
                     KYRLANLYNRENEIEKAKTYYKMAAEDDITEAKNNLAGIYFEEKDYENAIKYYEDAIA
                     VGCKSSLENLGDLYYQNQDIEKAISYYSRIPNNVSCQIKLGNIYEDLNNIEEAISWYK
                     KASENGDTRSSYRLGCIYESLGNTKNARKYFEMASSKNHMNARIHLGRIYFREGKLEE
                     SKMMFDTPANENNVYAQHMVGLIYDMFYKDYVNSKFWYEKARAQGCVESIYNLGQIYL
                     KLNDDAEAEKYYKEGIKYGSKKCEYMLAGLYYKKSLDMYISLANEEYDNCEEIVEGFP
                     NLNIDFDEVLIPPFKLQEEVIDEEEYVPIYILNIKESLDSMLEGLETEMIIDEEHDS"
     gene            19213..20139
                     /locus_tag="PC512_002319"
     CDS             19213..20139
                     /locus_tag="PC512_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HDF2442058.1"
                     /translation="MNFSNIFIQVAVLFIIILVGYFVRKFNLLDDHCTSKLSTLTMTV
                     FLPSMIISSMQINFDSKMIQKILLLLFTSLIMYIVSIIIAFLLKYILKCNDKKDLGIY
                     QYIVVFSNVAFMGYPVIEAVLGHEAIFYTAIFNLPFNLFSFTLGIYLLSKGSTSRGFS
                     IKSLISPATIAIVIGLFLFVTGLRLPQFINEPLEMLGSITTPISMIIIGSLLANSSAL
                     DCFVNKKLYIVTFIRLLVLPVIVYFILKGWINDKMILAIPVVISSMPAAANTAIMANQ
                     YDSNITLASQCVFFTTLFSVISIPFISILLLS"
     gene            20278..20424
                     /locus_tag="PC512_002320"
     CDS             20278..20424
                     /locus_tag="PC512_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442059.1"
                     /translation="MDMDLLFKIVFAIVAIGVSVKIIKTVASLAFKIALILLIILFVY
                     RMFL"
     gene            complement(20529..21053)
                     /locus_tag="PC512_002321"
     CDS             complement(20529..21053)
                     /locus_tag="PC512_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2442060.1"
                     /translation="MSKPIDITIRPIRREDAQAFNEIRRTYSVMRNTLALMSDRVDKT
                     EAMLASLGENDYMFVAETNNNGEKDVIGFAGLHVNSSPRLRHSAEIGISVAENYQGRG
                     VGKKLMEQLLDIADNWIMLTRVGLEVIVDNEKGLNLYKKLGFEIEGTKKYAVIRDGKF
                     EDVYIMGRYNKNLI"
     gene            complement(21106..21330)
                     /locus_tag="PC512_002322"
     CDS             complement(21106..21330)
                     /locus_tag="PC512_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442061.1"
                     /translation="MIIKLTKDNFNFRFKQYEGMFFHAEVVEGMESIRYKITKDKEGT
                     ELKEFGSTHIKDNMIYVPQVEAYIDLNSIK"
     gene            21527..22651
                     /locus_tag="PC512_002323"
     CDS             21527..22651
                     /locus_tag="PC512_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3810 domain-containing protein"
                     /protein_id="HDF2442062.1"
                     /translation="MSKKTKYFSLILFPIALLLNFIASKVPNIVEKYYSQFIDKIIVQ
                     ILSKVSGIFPFSLYEITMYIIVISIFLFLCCTLSTIFNKKKKLNIYLKNSILNILSIV
                     SIVYFLFVVLWGINYNRIPLETTLINNYNLKNNTSIQSKQYSVKELTKLYKFLVIKAN
                     ETRKLTLQDKNGIVKSNTDYNGVINRAQLGYDNILDILPGVSGSYSKPKYIISSNLMC
                     YTGITGIYFPFTGEANVNIAIPDLYIPCTVEHEMAHQRGFASEDEANFIAYLTSIKHP
                     NIDFNYSGYILALNYTASALSKVDYNAYVDISAGISDSVRRDLKNESEFWQKYEGKIN
                     EISNEFNNSYLKANSVTEGTQSYGKMVDLLLTYYELYPYN"
     gene            complement(23125..23949)
                     /locus_tag="PC512_002324"
     CDS             complement(23125..23949)
                     /locus_tag="PC512_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442063.1"
                     /translation="MRYKKISSLPILVVALLITGTTTTFSLSTTNSEKTNVYLANTVS
                     TVTKKVSDIQSSKGLVYNENIPLFINNSKIQYDDTPYHWPSNVISLTNSSEKAIMDYE
                     ITCLAYDKNGKPLELYWDAQNVAADGEVGSVGFSPAGVDYGIVTGISPVSPKSYSHTY
                     RKMQQSPPQDIISMFEKQQGKAWVENWLKEWKQMEKEYAKQNAIAPGKNQNDAFLLFD
                     KWKQSTGEHGVKYIISCVKQVTFNDGSVWKNSAYENWLKSFQGKEVSNSVLENYYK"
     gene            complement(24297..25352)
                     /gene="ispG"
                     /locus_tag="PC512_002325"
                     /gene_synonym="gcpE"
     CDS             complement(24297..25352)
                     /gene="ispG"
                     /locus_tag="PC512_002325"
                     /gene_synonym="gcpE"
                     /EC_number="1.17.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="HDF2442064.1"
                     /translation="MSYERRKTREVSVGTVKIGGENPISIQSMTNTDTRDADATIAQI
                     KRLEEAGCDIVRVAVPDIKAAKNIAKIKSSVNIPIIADIHFDYKLALEAIEQGVDGIR
                     INPGNIGSIERVKMVVEKCKERNLKIRIGVNGGSLEKELLKKYGSATAEALVESAMGH
                     IKILEDLDFHNIVISLKSSDIYKTVDAYELISKKVDYPLHIGITESGSVHKGTIKSSI
                     GVGALLLKGIGDTVRISLTGDPVEEVIVGKQILRSLGLLNDKIKVISCPTCGRCNIDL
                     ISVVNEVEEKIGSMEKNITVAIMGCAVNGPGEAREADIGIAGGKGEGLLFKKGEIVRM
                     IDGNKLVDELLEEIEKL"
     gene            complement(25534..26538)
                     /gene="rseP"
                     /locus_tag="PC512_002326"
     CDS             complement(25534..26538)
                     /gene="rseP"
                     /locus_tag="PC512_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HDF2442065.1"
                     /translation="MTIIAALILFSIIVLIHELGHFIFAKRSGIKVNEFSIGMGPKIY
                     SVKKDTEYSIRALPIGGYVSMEGEDEEQISPNSFGNKSILQRFSTIVAGPIFNIILAA
                     ILLVPVFLYIGSPTTKLGKIMPDTPAQAVGLQVGDKINKINGNSVKTWDEVANIINTS
                     SGGELKLSITRDGSDKVVNVTPKNNNGKYEIGIQPQREKDFLGSIVNACKTTVDMTKQ
                     MLTFLGQMITGRVPGGIGNAVAGPVGVIGMVSDAARTGIINVVYLAAVISLNLGIVNL
                     LPIPALDGWRILMLLLEAVRGGKKLDPNKEGMINVVGFGALMLFMLFITYKDILRLFQ
                     "
     gene            complement(26551..27705)
                     /locus_tag="PC512_002327"
     CDS             complement(26551..27705)
                     /locus_tag="PC512_002327"
                     /EC_number="1.1.1.267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate reductoisomerase"
                     /protein_id="HDF2442066.1"
                     /translation="MKKISILGSTGSIGKQTLDVVRDNRDKFEIVAISANSNIELLLE
                     QIVEFKPKYVTVFEENKALKLKEMLPKNIEIEVLAGMEGLKIISSLDEVDVLLTAVVG
                     MIGLVPTLCAIKKGIDIALANKETLVTAGELVMKEAEKYNVNILPVDSEHSAIFQCLN
                     GENKKNIEKIILTASGGPFRGKKKGELANITKNEALKHPNWSMGRKISIDSSTLMNKG
                     LEVIEARWLFGVEQENIDVVVHPQSIIHSMVQYTDSSIIAQLGCPDMRLPIQYALTYP
                     DRMESSFERMNFSKFSTLTFEEPDLETFPCLKLAYECLKMGGTYSSVLNSANEVLVSE
                     FLEDKIGFYDIPYYIEKTLEVHSSISEPTLEEILETDRWSRAYVANLIKK"
     gene            complement(27869..28072)
                     /locus_tag="PC512_002328"
     CDS             complement(27869..28072)
                     /locus_tag="PC512_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2442067.1"
                     /translation="MISYAPLWKLLIDRKIKKMEFVNISGISISVLGRLGNDKSVSMD
                     TMEKICLALDCKIEDVVEIKKSI"
BASE COUNT         9500 a         4454 c         3305 g        10881 t
ORIGIN      
        1 attgtatttt atcttataat atttactata atactatatt gcgaaaagag gtagaaaatg
       61 tttgcagaag aaagaatcca agctatatta aatatcctaa aaaaagaagg tagagttact
      121 gtcaaagagc tcagttctaa atttaatgtt acagaagatt gtataagaaa agatttaaaa
      181 aatatagaaa agatttcttc aataagaaga atttatggag gagctgtact agctagagaa
      241 acactagaga atcaggatac aaaagacaga aaagaaatta atattccaac aaagaaaata
      301 atagcagaaa aagcatttaa tttaattgaa gatagagaaa ctatattttt agatatctct
      361 acaattaaca tcttgcttgc gaagttgtta gctgaaagta ataaaaaagt aacacttgtt
      421 acaaatatgc tggatatact aaatgtagtt acttcaaaac caaataattt aaatataatt
      481 tccactggag gtttattaaa tctcagttta gacggttttg tcggtactcc aactatagag
      541 tttatatcga aatataagtt tgataagact tttatgggaa gttgtggagt agatgtattc
      601 aactcttcac ttacaacttt tgaaattgaa gatggtctta cgaagaaggc tataataaat
      661 tcaagtaaaa aagtatttat agttatggaa gataaaaagt ttaaatttga tggaaatttc
      721 aagtttgctc atttagaaga tattagttct ataattacag aaaaaacgcc tactcctgat
      781 atagtagata ttttatcaga atttaatgta aatgttttat aagtttaatt atatgtttta
      841 taggatttct tataaatata aatttttatt tgataaatat tcttaaaaac atatttctat
      901 aatatttatt ttatccttag tatctatttt ttaaaatcta gttctataac atctacttta
      961 tccttatgtc tatttataaa actaatttga aatagacttt ctaaatctaa tacagttatt
     1021 tttagaaagt ctatttcctt aaataaacta tttaatatta ctggctactt tttatatgaa
     1081 tacaataatt tgttattcat aaataaaagc ttatttcatt tcattcttca tttgcttctc
     1141 taattcttta gaaaatttct tttgttcata tctttccatc atctcatctt ttttcatttc
     1201 taagtttacc atagcacctt gtgcatcatc tttcaaatct tcagctgtat ttttcataac
     1261 ataagctgtc tttttaacac cttcttttaa atcttctttc atatttttca tatctctttt
     1321 taatctatcc atcaaaacta cctcctctgt aaatataata cttcctatat ttatttttcc
     1381 caaagtacat atatttattt gtaatatcaa ttataatttt taagtcttaa atatagttta
     1441 aactatctaa atctatacat ttcaataaat taaatatttt ttatttcaaa ataaaaataa
     1501 cactaagcat agattatatg ctcggtgtta ttttttaaat tcatagtaac ttaattgttg
     1561 ggttactata atgatgactt atatggagga tgtaaggaaa tctcatcatt atagttggtg
     1621 tattttatgg ttttaagctt ctttatattt atataataca gtttcattat gaattttttg
     1681 tgattttaaa atgaactatt attgaaagtt atatattctt tataataagt aattaatttt
     1741 taaattctac tgtgaatact acagagtttt ctttgttttt tatgctataa tcaaacccat
     1801 gacttttaaa aatttggctg actatataaa gtccaagtcc acttcctcca gtttttcttg
     1861 aacgagattt ttctattcta taaaatggat taaatatttc ttctaaataa cgtttctcga
     1921 tagttacacc agtattttca atttctaaaa ccactctttg attagaagtc tttttactta
     1981 ttcgtttatt tttatcatag agtctaatta taagctctga ttcttcagga gaatatttta
     2041 tggcattatt tattatatta ttgattgcct tagttattct ctcttggtct gctttaattt
     2101 ccaaattttc ttctattttt aaaatagttt tcatatgttt ttcttctatt aaaaatactt
     2161 gtctctttac aagtctattt aataattcac ttatatttat tgataccaat ttcaaatctt
     2221 tttcaagtat ttctgatttt gaaacctcta tcatttcatt tactaaatct tttaattctt
     2281 gtgtacactc atacgatttt ttcagataag tatccctatc cttatactta cctacactat
     2341 aaatcatacc ttcaatttga ccacttatta tggttattgg agtttttagt tcatgtgata
     2401 ttgtagcaac aaaatccttc cttctatatt cctgttctct ctcactctct attatgttta
     2461 taagaggctt tgttattaca attgaatata tatatgctcc aataatcgct atcaatattg
     2521 ctattgatat gatgtatggc attagttttc ttataacttc gtttgcttcg tcaattggtt
     2581 gtaatggcat aacgagttct aaagtatatg gaccatcttt tgcatcttta gtatatatag
     2641 gtatagaagt tctatactca tcctcaagac tattaatcat gtacttacta tatcttaaaa
     2701 taactacttc attcttacca tatacaattt taccttggtt atcttttaat aaaatagcca
     2761 aattttggtc tttagccata taataaagtc tttcttctaa agtatatgta tcgaaatgaa
     2821 ttgaactatc tactaaagat ttcaaacttt cttgaagaga ctcaatttta tactcatgat
     2881 aatatgatgg caataaaaaa tataaaatta gatatattat taaagctaat gctattaata
     2941 atgatgtcgt tattgaaaat aacttatact ttatacttaa cttttcccac ttatcaaata
     3001 tccttctcaa gtgtatatcc tattcctttt acagttttaa tatatggtaa tgatattttt
     3061 tttcttatat tttttatatg tgcatcaaca atcctagtat ctccataata gtcataaccc
     3121 catatactat ccaaaagacc ttccctagtt ataacttgtg gatacttttc tatcaaagct
     3181 tttaatatat taaactcttt tagtgtaagt tctataggtt ctccatctat ctctgcaata
     3241 tatgtgttta aatctaattt taatttttca aaaactataa atttgtcatt tatagtcttg
     3301 ttacttcgcc ttaaaattgc ttctactctt tttataagaa gattaaatga aaatggtttt
     3361 gttatataat catcacattc taagtcaaac cctttaagtt ggtctccttc atcatttaaa
     3421 gcagttaaaa atataattgg aacgcttgat gactttctta tcattttaca aactccataa
     3481 ccatctaagt ttggcatcat tatatctaat attactaaat cataacttcc ttgcttaaac
     3541 ttttgtatac cttccaaccc atcatttgct gtatcaactt gataaccttc tgcacttaaa
     3601 aattctgata ttaactcttg tatatttgaa tcatcttcaa ttacaagtat tgacgaattc
     3661 attctatcaa tcctttctat tttatttaaa atttcgtata ttacttatat tttatcttat
     3721 tgttgtgaat tttacatgaa aaaagagcta tcttaatttg taaattaatc cttttaattt
     3781 aaagatagct cttttggata cattttattt aatttattaa tctaatctct cttatatgcc
     3841 ttgaagtttt taagtctaag tgcatttgat acgactgaaa ctgaacttaa gctcattgct
     3901 gctgctgcaa tcattgggtt taataaaggt cctccaaata catataatat tcctgctgct
     3961 acaggtatac caattgtatt atatccaaat gcccaaaata ggttttgttt tatatttttt
     4021 atagtttcat gactaagttt aattgctgtt ggaacatcaa ttaaatcact cttcataagt
     4081 actatatccg cagattcaat ggctacatcc gttccacttc ctattgctat ccctatatct
     4141 gcttttgcaa gagctggggc atcatttatt ccatccccta ccattgcaac aaactttcct
     4201 tgattttgta gtttttcaac ttcttttgac ttatcttctg gtaaaacctc tgccaaaacc
     4261 atatctatac cgacttgatt tgctatagca tttgcagttt tcgcattatc tccagttacc
     4321 attgcaactt ttattcccat atcatgaagt atttctattg cttttttact actttctttg
     4381 actacatctg caactgctat tatacctgat aaatttccat ctacagctat atacataggt
     4441 gttttacctt ggcttgccaa tatatttgat ttttcttcta aatctccaag ctttatatta
     4501 ttgtcattca taagctttct atttccaagt aatatacttt catcattaat agtaacttgt
     4561 ataccagcac ctggtatagc tttaaaatta tcaacttttt caaattttat attcttctct
     4621 tctccatact taactattgc ttctccaaga ggatgttctg aacctttttc tgcacttgaa
     4681 gcaatcttga taagatattc ttcttttaca ttattattta atactatatc tgttactttt
     4741 ggctttcctt ctgttatagt acctgtctta tcaaatatca ctgtatttac tttatgtgca
     4801 gattctagtg cctctccacc ttttatcaag attccatttt ctgcgccctt tccagtccca
     4861 accattatag cagttggtgt tgctaatcct aatgcacaag gacaagcaat tacaagtact
     4921 gatataaata tagtaagtac aaatactata tcttttcctc ctattaaaaa ccacaataat
     4981 gatgcaacta cagctattgc aattactatt ggtacaaaat atccagatac agtatcggca
     5041 agtttagcaa taggtgcttt tgtaccttgt gcatcttcaa ctaactttat tatttgggca
     5101 agagcagtat ctccaccaat tttttcagcc ttaaacttaa taacaccatt tttattaata
     5161 ctagctcctg tcaccttact tccaacattc ttttctactg gtatactttc acctgtaagc
     5221 attgattcat caactgatgt atatccttct attacaactc catccacggg tattttagtt
     5281 cctggtttta ctaatagtat atctcctatc tctacttctt ctataggagt ttcaacttct
     5341 ttaccatcaa ctaacactat tgcagtttta ggttgtagcc ccataagctt tttaattgct
     5401 tctgatgttt ttccttttga ttttgattct aaatatttac caagtaagat aagtgctatt
     5461 attattcctg cactttcata atacaactga tgatggtgca taccttgaat ttgtccattg
     5521 gctatttgta gtgtcgtata tagactatat aaaaatgcgg ctaatgttcc tattgcaact
     5581 aaagaatcca tattagggct taaagaaaaa agtgatttaa acccatttat ataaaattta
     5641 taaccagcta tcattactgg tattactaaa attaactgaa ttaatgcata attaaaagta
     5701 tttgtcatag gatttataat ttctggcaaa ggccatggcc ctataggctt tattatcata
     5761 ggtcccattg ctatataaaa cagaggtact gcaaatacta ttgcaactat aaatttaaca
     5821 aataaagact tcatttctct ttcttttctc aatttatctt catccacatc aaccttattt
     5881 cttacctctt ctattggttt atatccagct ttttcaatag ctgcttttat ttgagataat
     5941 tttacttttg atgggtcata gtctatatta gctttatctg ttgcaatatt cacactaata
     6001 ctttctactc catccaattt ttttaccact ctctctacag cttttgcaca agctgcacat
     6061 gtcattccat caattttcat atcaattttt ttattacttt cttcctttat aattccatat
     6121 cctgcttttt ctacaacctg ctttatatca tcaaaattaa ccttagaatt atcatattct
     6181 attttaagtt tttcagtagc tatatttaca ttttggtcat atactccatc catcttctta
     6241 gttactctct ctactgcctt tgcacaagct gcacatgtca tacctgtaat tttataactt
     6301 tctaccactt tatttgaact cataataaaa tcttcctttc tttcaatata ttttcagcta
     6361 atttgtaacg ttttattttg atatgtaata ttgataaatt acttatttag aaatctatat
     6421 tttcattata ccccctatag gtatattaaa tcaatatttt tttaataaat aaatgtatta
     6481 gttatattta tttgtattta atagaaaagt atactcataa ttaaatgtat atataaaaat
     6541 agagcatcta aattgtttaa tgcttataca atttagatgc tctatttatt ataatttata
     6601 ttttatttaa aatttattct ttacatgctt caaaaaactc tgcttctgtt tcctttattt
     6661 caagctcatt gtctattatt ccaacagctt cttttttaaa tgctctacac tgacctatac
     6721 aaccagtctt tacattttct tctccaacca aagtttttag cttatttaca tccacatttg
     6781 aacagtttgg acatactctt atcatattta agttcctcct aattaatgtc taattaatac
     6841 ttttataccc aaatataaac tttataaaag tttttttaat ataaattatt accatatata
     6901 ccatttatat cctattgcga gtattacata ttaattttat atattattaa tactacatgt
     6961 acggtggtat ctgttgtttt ctcactattt ccaattcctt aatttctaaa gacttaatca
     7021 catttacttt atagttttct ttagacttta tatacaaaac atcttctatc tttttacctt
     7081 caataaattt atgagaccac ttaagaagtt cttcaaaatt acaaacttct tcttttacaa
     7141 aagtatcact ttcacttgca aaatatttaa ttattatttt ggttacttcc aacatatatc
     7201 atcctttact cttttattaa tctttttatc tattaaggtt attatttgtc taaaaaattt
     7261 ttttaaacag aataattttc agatgcaaaa ctaacagttt tatccaattt aaactatatt
     7321 aatacaattt aatatattcc tccttgtacc taataatata ttgtgctata attaataagt
     7381 tattttaatc gaagggagca acaaaaatgt cacaaaaaca taaaattata aatatcgcag
     7441 ttatagccca cgttgacgct ggaaaatcaa cattggttga tgctttcctt tctcaaagcg
     7501 gtgtttttag aaagaacgaa gtagttaaag actgcgttat ggacagtaac gaccttgaaa
     7561 aagaaagagg cataactata tattcaaaaa actgtgcaat aaactatgaa gattacaaaa
     7621 taaacatagt tgatactcca ggacacagtg acttttcttc tgaagttgaa cgtgttatga
     7681 aaactgttga cacagttatt ctattagttg atgctagtga aggcccaatg cctcaaacta
     7741 gattcgtttt acaaaaatct ttagagttcg gtttaaaacc aatattattt ataaacaaga
     7801 ttgataaaaa agaccagaga gcggaagaag tagttaatga agttttcgat ttatttgtag
     7861 acttaaatgc aacagatgag caatgcgaat ttcctataat atatggtatt gctaaacaag
     7921 gtattgctaa acttgaaatg gatgatgata gtgaagacct ttctcctcta tttaaaacta
     7981 ttgtaaatca cgttgaagct tatcctaatt acgataatga acctctacag ttccaaatat
     8041 cagctcttgc atatgatgat tatgtaggta gacttggtat aggtagaatt tacaaaggta
     8101 ctcttaaaaa caatacacaa gttgctatat gtagagaaga ttctgttgta tctaaaggaa
     8161 aagtatcaaa actttctgtg tatgaaggtt taaaacaagt tgaagttgat gaagctacta
     8221 gtggagaaat agttgttata gctggtattc ctgatatatc tataggtgaa actatatgcg
     8281 atttagatag tccactacct atggaaatga taaaaataga agagcctact ctttctatga
     8341 acttcttagt aaacgactct ccattcgttg gaaaaagtgg aaaattcgtt acaactagac
     8401 atttgaaaga tagacttgaa aaagaacttg aagtaaatgt tggtcttaaa gttgaacctc
     8461 ttgatactac tgatggatac aaagtttctg gacgtggaga gcttcactta tctatactac
     8521 ttgaaaatat gagacgtgaa ggttatgaag ttggtgtttc taaacctgaa gttttaatgc
     8581 ataaagaaga tggaaaacta atggaaccaa tagaaagagt tgttgtaaac tgtcctgaag
     8641 tttactctgg tactattata aatgaattaa acatgagaaa aggtatgatg gagtctatgt
     8701 caatagaagg agactatgta aaaatagagt tcttagcacc tactcgtggt cttttaggat
     8761 atcgaagtga atttataaac gctactcgtg gagaaggtac tttagttcgt tcatttgaaa
     8821 aatttgaaga atttaaagga gaaatacctt caagaggaaa tggtgtttta atagcacaag
     8881 gacctggtgt tactatgggg tattctctta atgccttaag tgatagagct gtaatgtttg
     8941 tagaccctgg tgtagaagtt tacgaaggta tgataattgg tatgaattcc agaaaagatg
     9001 atatggtagt caatccttgt aaaaacaaga aaatgagtaa cgtacgtgct tctggttcag
     9061 atgatgctat aaaattatct cctcctagaa tatttactct tgaagaagct ctagagttta
     9121 tagaagatga tgaattagtt gaaattacac ctgattctat aagacttaga aaaagattct
     9181 taaatgaaca tgatagatta agatataaca aatctagaca aggtaaataa aacgtacatt
     9241 tacctctaat taacaaaata gccatatagt actgaaaaat tatttcagtt tatatggcta
     9301 tttttatttg aaatttatat tattcaacat ttatataatt agctgcttga acggctgcaa
     9361 tagctccatc tgatgctgct gttattattt gacgtaaaaa cttagttcta ctatctcctg
     9421 ctacatatac accttctact gatgttgtac aagactcatc tgaaattata tatccacctt
     9481 catccaaatc aagaacattt tcaaacattt tattattagg tttaagacct atagcaataa
     9541 aaataccact aacatctata gttctttttt cttcagtctt taagtttttt acttctattt
     9601 tcgatacagt cttttctcct tctatttttt ctacaccatg actgtaaagt atctcaatat
     9661 tctctcttgc tttcacagat ttctccaaca cttcttcacc tctaaaacta tctcttctgt
     9721 gaattaaata cacttttgta caattattag ctaaaaataa agcatcttct agtgcagtat
     9781 ttcctccacc tactatagca acttctttat ctttaaaaaa ggctccatca catgttgcac
     9841 agtaagatac tcctctacct gtaaattctt gttcccctgc acaacctaat ttacgtcttt
     9901 caactccatt tgcaagaata acagcctttg ctttatgttc acctgaagaa gtttttacaa
     9961 cctttacttt tccctctaaa tttatctctt caacctcatc aaactgaata tcaacacctt
    10021 gagcaactgc ttgattgtat atattattag aaaattctac cccagaaatc ttttgaactg
    10081 ctggataatt ttctacctca gaggtacttg caacttgacc tccataaata tttttttcaa
    10141 atactgtaac gcttaaccct gctctcatag cataaattgc tgaagttaaa cctgctggtc
    10201 cagcaccaat tacaatgata tctaccataa cgtttacctc tctttatatt attatttctt
    10261 atatattatt ctcatcattc ttatacttta ctattattat ccatatatac tataaacaaa
    10321 acattatttt ttattaatta actttatttt acatatatat aaaaaaactg caaataaaaa
    10381 ttaactttta tttacagttc tcacttattt atataattca aaaccttatt ggttatcatt
    10441 tacagtgtct tctaatatat tgctttctga tatatatgat agaattgaaa gtccatacat
    10501 aaccaaaact aatgctgctg ttataagtac tattcccata tttaatacct ccttttgttt
    10561 acagtatact attattatgt gaaatattta tgaatttaat ttgaatatat atgtaatttc
    10621 acactaacaa tttcttcaaa ttaaacatta ttaactatat acttttgttg aaccaattat
    10681 gattaatagt ttaaatatta gcactattta cttatattta tatgatatac catataatta
    10741 catttttcaa attaaagttt tgtaaacttt ttttgtaata tagtgtagta taaaattgta
    10801 atattacaga tatttaatag ttatcttttg attactttca ttaaaaacag cttcatcact
    10861 atgaaaatct aggtttttaa acttttaaaa aagttaaaaa aatatttttc taatactcaa
    10921 tttgattaca atttttttac aatttaaaaa atattttttc caaattttta tattaatact
    10981 tgactttgtc tgttttataa actagaataa ttaataatat taagaatatt gaaaggcatt
    11041 gattaggaag agtaaatctg aatcgattac cagagaagga aactactagc tgaaatgttt
    11101 ccctaattag aaggattgaa aactacctag gagcttctat ccgaagttat cttaatgatt
    11161 ttagtaggaa tagacgtttt tattacttgc gttaaagtat caagtggatt ttttaaaatc
    11221 aatttgggtg gaaccgcggg aaacagattc tcgtcccttt tttagggatg agggtctttt
    11281 tttattacct aaattcagtt tttaaaatat tctgtatcta atttaattag ctaattaaaa
    11341 atttaaaata tatggaggat tataaaaaat gtattattca agtacgagag gcaccgaaga
    11401 aaaagtaact gcatcacaag caataataaa aggaatatca aatgatggtg gtctttatgt
    11461 tccaagtgaa tttcccaatg taaaaaatga acttataaat ttagtaaatt taacgtattc
    11521 tcagatagca ttttttgtac ttagtaaatt tttatgtgat tttactgaag atgaaattaa
    11581 aaattgtata gaaaatgcat atgatgaaaa gtttgattgt agtagtatag ctccattaaa
    11641 taaagtaaat gatacttatt tcttagaact atatcacggt ccaactttag catttaaaga
    11701 tatggcactt actataatgc ctcatcttct taaaacatct ataaagaaag ataatttaga
    11761 gaaagatgtt gtgattctta ctgctacatc tggagataca ggtaaagctg cacttgaggg
    11821 atttaaagat atagataaaa taaagataat tgtattcttc ccagaagatg gtgtaagccc
    11881 agtacaaaaa cttcaaatga aaactcaaac tggaaaaaat acatatgtag ttggtataaa
    11941 aggaaatttt gatgatgcac aatcaggtgt aaagaagatt ttttctgata aagaatttaa
    12001 tcaaaaacta ttggataata attatatatt atcttctgca aattcaatta atataggaag
    12061 acttcttcca caagttgcat actattttta ttcatatatg aaattagtta gcaatagtga
    12121 tataaattta aatgataaaa taaattttgt tgtcccaact ggtaattttg gtaatattct
    12181 agctggatat tatgccaaac aaatgggtct tccaataaac aaattaatat gtgcatcaaa
    12241 tgataataat gttctttatg atttctttaa aactggtgta tatgataaaa atagaacatt
    12301 gaaattaact acttctcctt ctatggatat attaatttca agtaatttag aacgattact
    12361 gtttgaaata tcaaatagaa atactgatat tgtaaataag cttttatcag accttagtga
    12421 taaaggagtc tacaaaataa gtgatgatat ggaaaaaaat ttagcctcat tctatggaga
    12481 atattcaaat gaagaagaag ttaaaagcac gataaacaat gtgtttaaaa attataatta
    12541 tttgatagat actcatactg ctgttgcata caattgttat gaaaaatata aaaaagaaac
    12601 ttctgataac acaaaaactg ttattgtaag tactgcaagt ccattcaagt tttctgaaga
    12661 tgttctaaag tctatagatt gtgattttaa agaccttgat gactttgcta taattgatag
    12721 attatcaagt atttctaaaa tagatattcc aaaacctatt aaaaatctta aaaatgcaga
    12781 aatactacat aaagatattt atgaaaaaga tgaattaaaa ctagctataa aaaaattctt
    12841 aaaggtatag gtgattatta tgttagagat tatagttcct gcaacaagtg ctaatatagg
    12901 tccaggattt gattgtcttg gaattgcgtt aaatatatac aataaatttt atgttgaaga
    12961 aattgaaagt ggtcttgaaa tagaaggttg tgaagatgct tacaaaaacg aaaacaactt
    13021 agtttataca tctatgaagt acttttttga tagagttaaa ccagaaaaaa tacctgctgg
    13081 tatcaaaata aaaatccaaa gtgaagtacc tatatgtaga ggtcttggca gtagtgcctc
    13141 ttgtatagta gctggagtta tagctgcaaa tgctctatca ggtgctaatt tagataaaaa
    13201 tcaattacta aatatagctt cagaaataga aggtcaccca gataatgttg ctcctgctat
    13261 tttaggaaat atgattgtat ctgttactga taatgagaat atacattatg atattataaa
    13321 aattcctgaa gaacttaaat tttgtgcaat gatacctaat tttaagttat caacagaaaa
    13381 agctagaggt gttttaccaa aggaaatacc atattctgat ggggtattca atgttagtag
    13441 agttgcttta ctaatatctg ccttactaaa caaaaacttt gacctactta aagtagcttg
    13501 tcaagacaaa ttgcatcaag attatagagg aactctaatt gagaactaca atgatattgt
    13561 tgaaaaatct gaacaattaa atagtattgg agtattttta agtggagctg gacctactat
    13621 aatgtcttta ataaaagaaa atgatgatag ttttgtggat aatatgaaaa attacctaca
    13681 aaaactaaaa tctgattggg aaataaaaga gttatgttgc gattctaatg gagctgtttt
    13741 aaatataata taattatcgt cttctataca aaatataact actcttttat tataatttgt
    13801 agtataataa ttaggactag gtaataatat taagtattat aatctagttc tttaaacatg
    13861 tttacattga ggagggatta tcataaaaga gttaataatt agagatttag ttgcaaaagt
    13921 tcctataatt caaggtggaa tgggcgttgg tatatctagg tcatcactag ctggtgcagt
    13981 tgctaagctt ggtggtgttg gtgtaatttc tggagttcaa attggatatg atgaggaaga
    14041 ttttgaaact aatactataa atgcaaattt aagagctata aaaaaacata tttctaaggc
    14101 caaagaaatc tcaaatggtg gtattattgg tattaatttt atggtagcta tgaaagaata
    14161 tgaaacatac gtaaaggaag ctgttaaagc tggtgtagac cttataatat ctggagctgg
    14221 attacctaat aagctaccat cattagtaaa gggaagtaat gtaaaaatag cacccatagt
    14281 ttcaactgca aaagctgcta atgtaatttt aaaaatgtgg gatagaaaag agaaaactac
    14341 tgctgactta atagttgttg aaggtccaaa agctggtggt caccttggat actctaacga
    14401 ggaacttgat aacatagatt ctatagacta tgataaggaa tttgttgaaa ttttaaaggt
    14461 tgcaaatact tatggagaaa aatttggtag aaacatacca gtagttgctg ctggtggtat
    14521 aacttctagt agtgatgtta aaaaatatat agatatgggt gcaagtggtg tacaagttgg
    14581 tacaagattt gttgctactt acgaatgtga tgcccatgag aactttaaaa tggcatacat
    14641 aaatgctagt gaagaagatg ttcatatagt taaaagtcct gtaggtcttc ctggacgtgc
    14701 cataagaaac aaatttatag aagaagttaa aataaatcgt ccagaaataa agaagtgcta
    14761 taattgtttg attccttgta atccaaaaga aactccttac tgtatttctc aagctctaat
    14821 caatgcagtt aaaggagatg ttgaaaattc acttttattt tgtggaaatg atgcctataa
    14881 aattgataaa ttaagtactg ttgaagatgt tatcaatgaa ttgatttctg aattataatt
    14941 taaagaaaac taaattaaaa ttttatcaag ctaaggagtt taaatacgtt atttattaat
    15001 ctttataaac atatttatgt ccttagcttt tttgtgtcaa tttcctttta ttgaaatttt
    15061 aatttaatta gagatagtat taacccttat aactaatctt cttttacaag tacattggtt
    15121 atttcagcta tatataaagt atgataatct ttttgtggat accatcttcc atctatacct
    15181 tcagcaataa aacattgggg ttcaagtttc tgactataca tttttttgca tataatagcc
    15241 attttagctt ccttaaaata aggtgtatca tttaagtgtt ctatattaaa tccaatctgt
    15301 gatatcttat cctcttctct accagatact tttccacaat atgaaagctc tttacgaaaa
    15361 tcttcatcaa aaaatgtaag agaaaattta tctgtattat ctataaattc cttagtataa
    15421 cgctgtggtc ttattactac aaaagcaaca tcttttcccc acataactcc aagccctccc
    15481 cagctagcag tcattgtatt cactttacct tcattttctg ctgttataag tgtccaatct
    15541 ttacctatca atccaaatgg attattttta atctcttctg ccaaaatttc tttaaaatca
    15601 ctcatatctc taataacctc tcattctctt atatttatat tccttttatt ttcatgataa
    15661 attataaatg aagtctagtt ttgaaaataa aatacttttt taaatatatt attgcaaata
    15721 agtaaatata tatatacact cttatttttt aatatattta ataatttcac tcagaatata
    15781 tatattcttt actcaaatta aatataactt atatacttta tgtgtaaatt atggtaaaaa
    15841 tattatttaa tcaaatcaaa acttgattta tatacctgga aaaggtatta tattaaagag
    15901 tgcttaaaat acgcatttca taaatagcta tatataaaat aataaataag gagagtgatg
    15961 ggcaatggat actagtccgt tgcggagaga attttttaca ttttcatcac ttaataatat
    16021 ctaaaatcaa aactaataca tatattcagt tatataaatt agttaattaa tagatactat
    16081 taaatgatga gatttatata aaactgaata aaggatgtgt tgccatgata agatattaca
    16141 aaactataga ttcaaaatta gagaaactta gtttttttga agatggctgt tggataaatc
    16201 ttgttgaacc taatcatagt gaaatcaacg aaatttctaa tttattaaat atagatgtag
    16261 aaagcataga atctgcacta gatgaagaag aacgctcaag aatagatgtt gaagacaatc
    16321 atactcttat acttatagat ataccagtag acgaaagtga ctctaattct tctcattata
    16381 ctacaatacc cttaggtatt atactaactg aagaagctat tgtaacagtt tgtgatgcac
    16441 aaactaagat tttaaatgac tttatagttg gtcatattaa agattttttt acgtttaaaa
    16501 agactcgctt tttgcttcaa attcttcaca aaaatgcagc ttattacttg cattacttaa
    16561 gaaaaataaa taaaatgaca atcataatag agcgagaaat ttacaaatca atgaaaaaca
    16621 aagaattggt tcaattattg gaattagaaa aatctttggt atacttctct acctcactaa
    16681 aatctaatga acttgtttta aacaaaatgg ttagaactgc tggtataaag aagtatccag
    16741 atgatgaaga cctattagaa gatgttatag ttgaaaatag acaggctctt gatatggcta
    16801 aaatatatgg agatatattg agtagaatta tggatgcttt cagtgcaatt ataagtaata
    16861 atcagaataa tgttatgcaa attttaacag tagttacact aattttctca atacctacaa
    16921 taatatcagg attctttggt atgaatgtca tcaacatgcc attttctaat aacccaaacg
    16981 gattttggat aatacttctt attacctcta taatatgtat agtgattaca tttttcatgt
    17041 caagaaataa gctattataa aatattaata aaaaagccat tagaattaat tgatttacat
    17101 ttatcctaat ggcttttata tatttaaatc tatataatct tataatactt tttaactatc
    17161 atgttcttca tctataatca tttcagtttc aagcccttct agcattgaat ctaaactttc
    17221 ttttatattt agtatataaa ttggtacata ctcttcttca tctattacct cttcttgcaa
    17281 cttaaatgga ggaattaata cttcatcaaa gtctatattt aaatttggaa agccttctac
    17341 tatctcttca caattatcgt actcttcatt tgctaaagaa atgtacatat ctaggctctt
    17401 tttataataa agacctgcaa gcatatactc acacttctta cttccatatt taataccttc
    17461 tttataatat ttctcagctt ctgcgtcatc atttaatttt aaataaattt gacctaaatt
    17521 atatattgat tcaacacaac cttgtgctct agccttttca taccaaaatt tagaatttac
    17581 ataatcttta tagaacatat cataaattaa tcctaccata tgttgagcat acacattatt
    17641 ttcattggca ggtgtatcaa acatcatttt agactcttcc aatttacctt ctctaaaata
    17701 aattctacct agatgtatac gagcattcat atggtttttg ctacttgcca tttcaaaata
    17761 ctttctagca ttttttgtat ttcctaagct ctcatatata caccccaatc tataactaga
    17821 cctcgtatct ccattttcag atgctttctt ataccaactt attgcttctt caatattatt
    17881 taaatcttca tagatatttc ctaatttgat ttgacaagat acattatttg gaatcctcga
    17941 ataatacgaa atcgcttttt ctatatcttg attctgataa tataaatccc ctagattttc
    18001 aagggaactt ttgcatccaa cagctatagc atcctcataa tatttaatag cattttcata
    18061 atctttttct tcaaaatata tacctgccag attatttttt gcttctgtta tatcatcttc
    18121 agcagccatt ttataataag tttttgcctt ctctatctca ttttctctat tatataaatt
    18181 agcaagtcta tacttagaaa gtgtatgatt tttttctatt gctttctcat aataataaat
    18241 tgcatctccc agctcttctt ttctatcata tacatatgca agcctatact cagacttcac
    18301 atcatctcta tcagcactct ttttataata cttctctgca tcttctaaat tatcatttat
    18361 ttccataatc atacccaagt taaagcaacc tttcatatga cctgacttgt acaactgttt
    18421 atataaactt actgttgatt tattatcttt cttttttcca tttaatattg ctaaattata
    18481 ttttgcatca tcatctaaaa gcacagaacc ttttttatag tattcatatg cttcatcatc
    18541 tttctccaaa aaagtatata atacccctaa attaaaacaa gctttaccta aattcttgtc
    18601 tgctgctgtt tttaaccatt tttcacacct tacaaaatct ttcattttaa aatggcatac
    18661 acctaaatta ttttgtgctt gtaaataacc taaatttgct atcttttcat accaatatat
    18721 agcatattca tagccatcta acttatagta catattacct aaatcaaaag cagcatcttc
    18781 acttccactt ttatatgcca ttgaatacca cttttctgct tctttaaatt gttttttact
    18841 ttcatatata tttcctaaag tatattgaga ttttacgtaa ttatccaatg cagcactctt
    18901 atacaactct attgcgcttt ccatcttacc catcttttca aggagggcac ccttagtatg
    18961 tacgactttc gggtcattag atatattttt tatttttttt atagaaaatt ttgtattttt
    19021 cattattcgc tacctaccca ttttataaaa tatattctct caaacattat tatacattat
    19081 aatctacaat taatgctata atattgaatt tttacctttt gtcactatat tgtaacatta
    19141 aattttaaat tttataatca ttagatttta ttatgtaatt ggtatataat gtatatatag
    19201 gggggacatt ttatgaattt cagcaatatt tttatccaag ttgcagtttt atttataatt
    19261 attttagttg gatattttgt cagaaaattc aacttattag atgaccactg cacatctaag
    19321 ctttcaactt tgacaatgac agttttttta ccatcaatga taattagctc catgcaaatt
    19381 aactttgata gtaaaatgat acaaaaaata ctattgttat tatttacatc tttgattatg
    19441 tatatagttt caattataat tgcattttta ttgaaataca ttttaaaatg taatgataaa
    19501 aaagatttgg gaatatacca gtatatagtt gttttttcaa atgttgcttt tatgggttat
    19561 cctgtaattg aagcagtttt aggtcatgaa gcaatattct atactgcaat attcaatttg
    19621 ccttttaact tattttcttt cactttagga atttatcttt tatctaaagg cagtacaagt
    19681 agaggttttt caataaaatc acttataagc cctgctacaa tagctattgt tattggactt
    19741 tttttatttg taacaggact taggttaccc caatttataa acgagccact tgagatgttg
    19801 ggaagtataa ctacaccaat atccatgatt atcattggaa gcttacttgc taattcttca
    19861 gctctcgatt gttttgtcaa caaaaaatta tatatagtca cttttataag attattggta
    19921 cttcctgtga ttgtgtattt tattctaaaa ggatggataa atgataagat gattttagct
    19981 ataccagtag taatttcttc aatgcctgct gctgcaaata ctgctataat ggctaatcaa
    20041 tatgactcca atataacact agcttcacaa tgtgtgtttt ttacaacact attttcagtt
    20101 atatctatac cttttataag tattttactc ttatcttgat ttattttttt atgtattata
    20161 taataacata ttcaataaat tacaaatata aacattttat tgtagtatat tgatggaatt
    20221 ttttcctaga tatttgtcaa taatatctat atgtattata gaataggagg cttaaatatg
    20281 gatatggatt tactctttaa aatagtattt gctatagttg ctataggtgt ttctgtaaaa
    20341 atcattaaaa ctgttgctag tttagctttt aaaatagcgt tgatattgct aataatttta
    20401 tttgtatata gaatgttttt gtaaacattt aaaaataagt tttttaacac aatagagaag
    20461 taaaatagat tatctttaat gtaaattttt tattaaagac actctatttt acttctctat
    20521 tagcttattt aaattaaatt tttattatat cttcccataa tataaacatc ttcaaatttt
    20581 ccatctctga ttacagcata ttttttagtt ccctctattt caaaacctag ctttttatat
    20641 aaatttaatc ccttttcatt atccacaatt acttctaatc ctactctagt taacataatc
    20701 caattatctg ctatatctaa aagttgttcc ataagcttct tacctactcc tcttccctga
    20761 taattctctg caacacttat tcctatttct gcgctatgtc tcaatcgtgg agaagaattt
    20821 acatgtaacc cagcaaaacc tattacatct ttttctccat tattattagt ttcagctaca
    20881 aacatataat cattttctcc caaagaagct aacatagctt cagttttatc gactctgtca
    20941 ctcattaatg ccaaagtatt tctcataaca ctgtatgttc ttctaatttc attaaaagct
    21001 tgtgcatctt ctcttcttat aggtcttatt gttatatcta taggcttact catattggat
    21061 tccccctcaa acataatctt tatttttaat taaaatttta catctttatt ttatactgtt
    21121 caaatctatg tatgcttcta cctgaggtac atatatcata ttatctttta tatgtgtact
    21181 tccaaattct tttaattctg taccttcttt atccttagtt attttatatc taatggattc
    21241 cataccttca actacttcag catgaaaaaa cataccttca tattgtttaa atctaaaatt
    21301 aaaattgtct ttagtaagtt ttattatcat atttttatct actccttata taattgatat
    21361 ttttcttatt attagttgta tatatactgc ttattcatat taatatatta taacttatca
    21421 tttatttagt ataaagttat aaatagatat atttatactt attttacaat ctttcttcaa
    21481 ttgatatata atatgtttat ataaactaat gtatgtgagg tgaaatatga gcaaaaaaac
    21541 aaaatatttt tctttaattc tctttcctat tgctttgctt ttaaatttta tagccagcaa
    21601 agttccaaat attgttgaaa aatattactc ccaattcata gataaaataa ttgtacaaat
    21661 attgagtaaa gtttctggaa ttttcccatt ttctctctat gagattacaa tgtacataat
    21721 agttatatct atcttcttat ttttatgttg tactttatct acaattttta ataagaaaaa
    21781 aaaattaaac atatatttaa aaaattccat tttaaatata ttatccattg tatcaatagt
    21841 ctactttctt tttgtagtgc tttggggaat aaactataat aggattccac tagaaaccac
    21901 acttataaat aactataatt taaaaaacaa tacctctatc caatcaaaac aatatagtgt
    21961 taaagagctt actaaattat ataaattcct tgtaattaaa gcaaatgaaa ctagaaaact
    22021 cacattacaa gataaaaatg gtattgtaaa atctaataca gattataatg gtgtcataaa
    22081 tagagctcaa ctaggatacg ataatatctt ggatatatta cctggtgtta gtggtagtta
    22141 ttctaagcct aagtatatta tttcatcaaa tctaatgtgc tatacaggaa taactggtat
    22201 atactttcct tttacaggtg aggcaaatgt aaatatagca atacctgact tatatattcc
    22261 ttgtacagtt gaacatgaaa tggcacatca aaggggattt gctagtgaag atgaggctaa
    22321 ttttatagcg tatcttactt ctataaaaca ccccaatatt gattttaact attctggata
    22381 tattttagct ttaaattata ctgcttctgc tttaagtaag gttgattata atgcatatgt
    22441 tgatatttct gctggcattt cagattctgt ccgtagagat ttaaaaaatg aaagtgaatt
    22501 ttggcaaaaa tatgaaggta aaattaatga aatttctaat gagtttaaca attcttactt
    22561 aaaagctaat agcgttactg aaggtactca gagttatggt aaaatggttg atttattgct
    22621 aacttattat gaattatatc catataacta aacactacaa ttcaaaattt tattcatata
    22681 cagctgatat taaatcagct gttttctatt taaataaatt atttaacttc aagcaatctt
    22741 atataatttg atagtactta tactatctgt ataacatttc aattctaact attttagtta
    22801 aaacatttct attatctttt ttaataaatg ttttaactaa aatttttaaa acataaaact
    22861 tccacattat ttcactatct atataaaaat ctaaaaattc acatataaaa ttacataact
    22921 aaaaaatcat aaatttatag aaaacatata ttcaaaataa aaaagcatgt atcaaaactt
    22981 gacacatgct tataatctta tgtatatata tcattttgtc acaataaaaa tttacttgta
    23041 acactgatat ttttaaacaa aatagtcctt atttaattaa attaacatta attaaattcg
    23101 tactcatttt gctatcatta aacattactt atagtaattt tctaatacac tatttgaaac
    23161 ttccttccct tgaaaacttt tcaaccaatt ctcatatgct gagtttttcc atacactacc
    23221 atcattaaat gttacttgtt ttacacaaga tataatgtac tttacaccat gctctccagt
    23281 tgattgtttc catttatcaa acaatagaaa ggcatcattt tgattcttac ctggtgctat
    23341 tgcattttgc tttgcatatt ctttctccat ttgtttccat tctttcaacc aattttctac
    23401 ccatgccttg ccttgttgtt tttcaaacat acttattata tcctgtggtg gtgattgttg
    23461 catttttcta taagtatgtg aatatgattt tggagacaca ggagatatgc ctgtaacaat
    23521 accatagtct acaccagctg ggctaaatcc aacacttcct acttcgccat ctgctgccac
    23581 attttgagca tcccaatata gctcaagtgg ttttccattt ttatcatatg ctaagcatgt
    23641 aatttcataa tccataattg ccttttcact gctatttgtt aagcttataa cattgctagg
    23701 ccaatgatat ggagtatcat catactgtat tttgctatta tttataaata atggaatatt
    23761 ctcattataa acaagacctt tactactttg aatatctgat accttctttg tgacagtact
    23821 taccgtattt gctaagtata catttgtttt ttctgaattg gtcgtactaa gagaaaatgt
    23881 tgttgtcgtt ccagtaatca gcaaagcaac aactaaaata ggtaagctag atattttttt
    23941 atatctcaca attcttcacc tctttttcta ttaacttata ataaaacaat ttaccaaaac
    24001 attaaaatct atgttaacat aatttaccaa ctgttctagt aactatatcc tatcatagtt
    24061 actatcaagt ttcaatacta ttgatggaaa ttttcactat attaaatctt tttttaattt
    24121 tataaattta caatatgatt taactcatac atatatagtc aaattagaat ataagtttct
    24181 tacatttaat gaagtttata aaataaaaaa tgactagata attaaatact gtaaataaaa
    24241 acttattaca aaagtattta aaaatctagt caattaatat atatatgaat tgtatactat
    24301 aatttttcaa tctcttctag caactcatca actaatttgt taccatcaat cattctaact
    24361 atttcaccct ttttaaataa aagaccttca cctttacccc cagcaatacc tatatctgcc
    24421 tctctggctt caccaggtcc atttacagca cagcccataa ttgcaacagt gatatttttt
    24481 tccatactac caatcttttc ttcaacctca tttacaacac taattaagtc tatattacat
    24541 ctaccacatg tagggcatga tataacttta atcttatcat ttaaaagtcc caaacttctt
    24601 aaaatctgtt taccaacaat aacctcttca acagggtcgc ctgttaaaga tattctaaca
    24661 gtatctccaa ttcctttaag aagaagtgct cctaccccta tagaagactt tattgttcct
    24721 ttgtgaacac ttccagattc tgtaattcca atatgaagag gataatcaac tttttttgat
    24781 attaattcat atgcatcaac agttttataa atatcggatg attttagaga tataactata
    24841 ttatgaaaat ctaagtcttc aagaatctta atatgtccca ttgcactttc aactaatgct
    24901 tcagcagttg cagagccata cttttttaaa agttctttct ctaaagaacc tccattaact
    24961 ccaattctaa tttttaaatt tctttccttg catttctcaa ctaccatctt aactctctct
    25021 atacttccaa tattaccagg atttattctt attccatcca caccttgttc tatagcttca
    25081 agggctagct tataatcgaa atgtatatct gcaataattg gtatatttac actagacttt
    25141 atctttgcta tatttttagc agctttaata tcaggaacag caactctaac tatatcacaa
    25201 ccagcttcct ctaatctctt tatttgagct attgtagcat ctgcatctct tgtatcagta
    25261 tttgtcatag attgtatact tataggattt tctcctccta tttttacagt tcctacactt
    25321 acttctctcg tctttcttct ctcgtaactc atattccacc tctatatatt attttatatt
    25381 gaatctcttt aaatattaaa atattataac ctacatgtat attataaatt aaaaagctat
    25441 ctagttaaat aagaataaat ttcatatata aaaattaatt tattcttatt taaaactaca
    25501 tagcctattt tcttaaaatc tctaaaaact aaatcattga aataatctta gtatatcttt
    25561 atatgtgata aaaagcataa ataacattaa agctccaaaa ccaacaacat ttatcatgcc
    25621 ttctttattt gggtcgagtt ttttaccacc tctaacagct tctagtaaca gcataagtat
    25681 tctccatcca tcaagtgctg gtattggtaa tagatttact atacctaaat ttaagcttat
    25741 gacagctgct aaatacacta catttatgat gcctgtacga gcagcatctg ataccatacc
    25801 aataacacct actggtcctg ctacagcatt gccaatccct cctggtacac gtcctgtaat
    25861 catttgacct agaaatgtta gcatctgttt tgtcatatct acagtagttt tacatgcatt
    25921 tactattgac cccaaaaagt ctttttctct ttgtggttga atccctattt catactttcc
    25981 attgttattt ttaggtgtta catttacaac tttatcactt ccatctctag ttatactaag
    26041 ttttaattct ccaccagaag aagtatttat tatatttgca acttcatccc aagtcttaac
    26101 agaattacca ttaattttat ttatcttatc tcctacttga agccctacag cctgtgcagg
    26161 agtatctggc attatctttc ctaatttagt cgttggagaa cctatataca aaaatactgg
    26221 aactaaaagt attgctgcta atattatatt gaatattggt cctgctacaa tagtactaaa
    26281 tctttgtaat atagacttgt ttccaaaaga atttggactt atttgttctt catcttcacc
    26341 ttccatgctg acatatccac caattggaag tgctcttata gaatactctg tatctttttt
    26401 tacactatat atcttaggcc ccatacctat agaaaactca tttactttga taccacttct
    26461 ttttgcaaat ataaaatgtc ctaactcatg tattaataca attatactaa atagtattaa
    26521 tgcggctatt atagtcataa attcaccttc ctattttttt atcagatttg caacataagc
    26581 tctactccat ctatctgttt ctaagatttc ttctaatgtt ggttcactta tgctactatg
    26641 aacttctaaa gtcttctcta tgtaatatgg tatgtcatag aaaccaattt tatcctctaa
    26701 aaattcactt actaaaactt catttgctga atttaaaaca gaggaataag ttcctcccat
    26761 ttttaaacac tcatatgcca attttaaaca tggaaaagtt tctaaatctg gttcttcaaa
    26821 agttaaagta ctaaattttg aaaaattcat tctttcaaag ctactttcca ttctatctgg
    26881 atatgtaaga gcatactgta ttggtagtct catatctgga catcctaatt gagcaattat
    26941 tgagctatct gtatactgca ccattgaatg aattatgctt tgtgggtgaa ctactacatc
    27001 tatattttct tgttctactc caaataacca tctagcttct atcacttcaa gtcctttatt
    27061 cataagcgtt gaagaatcaa tacttatttt tcttcccata ctccaatttg gatgcttcaa
    27121 agcttcattt ttagttatat ttgcaagttc tccctttttc tttcctctaa atggaccacc
    27181 agatgctgta agtattatct tttctatatt ttttttattt tctccattta gacattgaaa
    27241 tatagcacta tgttcactat caacaggaag aatatttaca ttgtattttt ctgcttcttt
    27301 cattacaagt tcaccagcag ttaccaacgt ttctttattc gctaatgcta tgtctattcc
    27361 cttctttata gcacaaagag ttgggactaa tcctatcata cctactacag cagttaaaag
    27421 gacatccact tcatcaagtg atgatattat ttttaatcct tccattcctg ctaaaacttc
    27481 tatttctata tttttaggca acatttcttt taatttcaat gctttatttt cctcaaaaac
    27541 tgttacatat ttaggtttaa actctactat ctgttctagc aataattcaa tattactgtt
    27601 agctgatatt gcaactatct caaacttatc tctattatct ctaactacat ccaaagtttg
    27661 tttacctata gagcctgtag aacctaaaat tgatatcttt ttcatataat aatcctttct
    27721 aataataaat ataccctgtc aaaacattat aacactacta aaacaattat ttttactatt
    27781 catagaaatt tcatatatta ttccacagat taaaattaat ctattatttt ttgtattttg
    27841 tggaatatta taaaatattc tagtattatt aaatgctctt ttttatttcc acaacatctt
    27901 ctattttaca gtctagtgct aaacatatct tctccattgt atccatagaa acagatttat
    27961 catttcctag tctgcctaaa acagaaatac ttatacctga tatatttaca aattccattt
    28021 tctttatttt tctgtcaatt aacaatttcc ataatggagc gtatgaaatc atgttatcac
    28081 ctcgcaaaat atattctatc acattttatc tattttggaa aattttcatc tatttagata
//
LOCUS       DAMJVG010000049        27366 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.049, whole genome shotgun sequence.
ACCESSION   DAMJVG010000049 DAMJVG010000000
VERSION     DAMJVG010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27366)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27366)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27366
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.049"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(<1..896)
                     /locus_tag="PC512_002329"
     CDS             complement(<1..896)
                     /locus_tag="PC512_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009243519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HDF2442068.1"
                     /translation="MKLKHIAIIGSLFPILFSIVLFFGVLMSADSDDENSNFSSGITG
                     MNLSAEVLKHQPMVEKYAKEYGISEYVNVLLAIIQVESGGTAKDVMQSSESLGLPPNS
                     LDTESSIKQGCKYFASLLSSCKNQGINDLNVAIQSYNYGGGYVGYVAGKGKKHTFNLA
                     ESFAREKSGGKKVTYTNPIAVAKNGGWRYGYGNMFYVELVNQYLTVPQVSGELAQKVM
                     NEALKYQGWKYVYGGSNPNTSFDCSGLTQWCYGKAGISLPRTAQMQYDATQHIPLSQA
                     KAGELVFFHSTYNAGSYVTHVG"
     gene            complement(893..3085)
                     /locus_tag="PC512_002330"
     CDS             complement(893..3085)
                     /locus_tag="PC512_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HDF2442069.1"
                     /translation="MKERIQSAFTKKKIFHFLKMALFVVALSLILLSLLGTVAHATGL
                     VDDTINAENLYSKYPLSNYQLDFYVDNSWAWLPWNWLDGIGKSVQYGLYCITNFVWTI
                     SLYLSNATGYVVQEAYKLDFINDMADSIGQSIQTLAGVTSSGFSTSGFYVGFLLLIIL
                     VVGLYVAYTGLIKRETSKALHAVINFVVVFILSASFIAYAPDYIKKINEFSSDISTAS
                     LDLGTKIMLPNSDSEGKDSVDLIRDSLFSIQVEQPWLLLQFGNSNAEEIGTDRVEALV
                     SASPENEDGKTREEVVKTEIESNDNNNLTIPQVVNRLGMVFFLLFFNLGITIFVFLLT
                     GMMLFSQILFIIFAMFLPISFLLSMIPSYESMAKQAIVRVFNTIMTRAGITLIVTVAF
                     SISSMFYNISTDYPFFMVAFLQIVCFAGIYMKLGDLMSMFSLNANDSQSMGRRIFRRP
                     YLYMAHRARRMERRLAGAVTAGGVAGAVAGSTVSNARTTRNNSAKDNRGNTSSSMGQR
                     AGSKVGAVLDTKNKVKDKANAMKETVKDIPTQTAYAVHSAKEKAKTSVSDFKRGMVQE
                     QQSRQSGRLEKQEQHKKNIADKRMELQKAQEARQARKTDGSATTGATRPHERPVTASA
                     IPKTNVEKTQEVKRPATTSTSKAGEPVKTNSVKERPLSSGTSDGKIPQSAQTVHSKNV
                     EKVVSHETHQNYKAERTTKAQTVEQAKRTTEHTEKNRNLVTKKGQKKK"
     gene            complement(3085..5535)
                     /locus_tag="PC512_002331"
     CDS             complement(3085..5535)
                     /locus_tag="PC512_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2442070.1"
                     /translation="MFPIKYIDNNLVWNKDNEVFAYYELIPYNYSFLSAEQKFIVHDS
                     FRQLIAQSREGKIHALQIATESSIRSMQEQSKRLVTGKLKEVAYQKIDEQTEALVSMI
                     GDNQVDYRFFLGFKLMVTEEQLNLKNLKKSAWLTFKEFLHEVNHTLMNDFVSMPNDEI
                     NRYMKMEKLLENKISRRFKVRRLEINDFGYLMEHLYGRDGIAYEDYEHQLPKKKYKKE
                     TLIKYYDLIRPTRCVIEESQRYLRLEHEDKESYVSYFTVNAIVGELDFPSSEIFYFQQ
                     QQFTFPVDTSMNVEIVENRKALTTVRNKKKELKDLDNHAYQAGSETSSNVVDALDSVD
                     ELETDLDQTKESMYKLSYVIRVSADDLDELKRRCDEVKDFYDDLNVKLVRPAGDMLGL
                     HSEFLPASKRYINDYVQYVKSDFLAGLGFGATQQLGENTGIYMGYSVDTGRNVYLQPS
                     LASQGVKGTVTNALASAFVGSLGGGKSFCNNLLVYYSVLFGGQAVILDPKSERGNWKE
                     TLPEIAHEINIVNLTSDKDNAGLLDPFVIMKNVKDAESLAIDILTFLTGISSRDGEKF
                     PVLRKAVRSVTQSETRGLLHVIDELRCEDTAISRNIADHIDSFTDYDFAHLLFSDGTV
                     ENAISLDNQLNIIQVADLVLPDKDTTFEEYTTIELLSVSMLIVISTFALDFIHSDRSI
                     FKIVDLDEAWAFLNVAQGEILSNKLVRAGRAMQAGVYFVTQSSGDVSKESLKNNIGLK
                     FAFRSTDINEIKQTLEFFGIDKEDENNQKRLRDLENGQCLLQDLYGRVGVVQIHPVFE
                     ELLHAFDTRPPIQRNEVE"
     gene            complement(5522..5911)
                     /locus_tag="PC512_002332"
     CDS             complement(5522..5911)
                     /locus_tag="PC512_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDF2442071.1"
                     /translation="MKKIRSYTGIWNVEKVLYAINDFNLPFPVTFTQITWFVITEFII
                     ILFGDMPPLSMIEGAFLKYFGIPAFLTWFMSQKTFDGKKPYSFLKSQITYALRPKITY
                     AGKAVKLQKEIFNETITAVRSVSYVPD"
     gene            complement(6029..6532)
                     /locus_tag="PC512_002333"
     CDS             complement(6029..6532)
                     /locus_tag="PC512_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HDF2442072.1"
                     /translation="MIDDMAVYIANLGKYNEGYLVGAWFTFPIDEEDVKEKIGLNEQY
                     EEYAIHDTDNFPIEIGEYVSIDELNEMYEMIEELPDYIVDCLDEFIGHYGTLEEVVEH
                     KDDIYYYPDCETMTDVAYYYIDELQALGDIPPSLQNYIDYEAYGRDLDMGGCFIATSR
                     GMCEIPY"
     gene            complement(6535..7038)
                     /locus_tag="PC512_002334"
     CDS             complement(6535..7038)
                     /locus_tag="PC512_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HDF2442073.1"
                     /translation="MQETRVLVETKRTTGEETTSYWFDLPIEVAEFEEKLGVSTESQD
                     YRIIEKLLPYADEVHEHTSVYQLNELDYMYRQLSSDMQEEYTMLHTVYENLEALYICR
                     NVITLYPDCKSMIDVARQKLMNDPTFKHLSEDCQEYYFDFETYASHLQEHGKFLVTEH
                     GIFELPE"
     gene            complement(6957..7253)
                     /locus_tag="PC512_002335"
     CDS             complement(6957..7253)
                     /locus_tag="PC512_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005339688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDF2442074.1"
                     /translation="MNDIFRDMQAKVGCENISDLPSYKRKVWHEMKQLNLADYEEKQL
                     EDFSKYVFGMSCQTLKDVMKQQKGREEQCRKQGYWWKRKEQLAKKQHHTGSTCR"
     gene            complement(7350..7952)
                     /locus_tag="PC512_002336"
     CDS             complement(7350..7952)
                     /locus_tag="PC512_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2442075.1"
                     /translation="MDKVVIYIHGKGGNAEESSHYKPLFSDCDVVGLNYTAQYPWEAK
                     EEFPSLFDLICKHYKSVQIVANSIGAYFAMNALSDKQIEKAYFISPIVNMEKLIADMM
                     YWANVTEDELRDKKEIKTTFGETLSWEYLCYVKENPTTWKIPTNILFGEKDNLTSYAT
                     ISEFTKQTNATLTVMRNGEHWFHTEEQMKFLDEWINKSAR"
     gene            complement(8037..8198)
                     /locus_tag="PC512_002337"
     CDS             complement(8037..8198)
                     /locus_tag="PC512_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442076.1"
                     /translation="MAIVVIGIYLGFKREFSKLIGFLVVALVAVGLVFNAGGVKDVLL
                     ELFNKIIGA"
     gene            complement(8365..10275)
                     /gene="ltrA"
                     /locus_tag="PC512_002338"
     CDS             complement(8365..10275)
                     /gene="ltrA"
                     /locus_tag="PC512_002338"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HDF2442077.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNHILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
     gene            complement(11017..11151)
                     /locus_tag="PC512_002339"
     CDS             complement(11017..11151)
                     /locus_tag="PC512_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017143882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HDF2442078.1"
                     /translation="MWELLKDLLLVSFGMGIGVVLMCILTVGKEADRCMEEIKEREDN
                     "
     gene            complement(11159..12358)
                     /locus_tag="PC512_002340"
     CDS             complement(11159..12358)
                     /locus_tag="PC512_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HDF2442079.1"
                     /translation="MNETDFLTALKEKRCAYGVSQTRLAIMANISREHLSRIEAGKVT
                     LTEDMKHTLLEAVEKFNPNNPMFLLFDYVRIRFPTMDIKHIIKDILKLNIGYMLHEDY
                     GHYKYTEHYHIGDVFVYVSQDEEKGVLLELKGKGCRQFESYLLAQERSWYDFFTDALV
                     EGGVMKRLDLAINDRTGLLDIPELIRKCENEECISKFRSFKSYGSGELVKHNETDKYG
                     MGHTLYIGSFSSEVYFCCYEKNYEQYAKLGIPIEEVPIKNRFEIRLKNERAYYAVVEL
                     LTHYDAELTAFSIINQYIRFADKEPDKRKSDWKTNVRWAWFIGEGRPPVKLTTQPEPY
                     TLERTLNWLQRQVAPTLKMLKQIDKDNQTEYLETIEKQAKLTERHYQIIKQQTATVEE
                     MVANVKE"
     gene            complement(12560..13954)
                     /locus_tag="PC512_002341"
     CDS             complement(12560..13954)
                     /locus_tag="PC512_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008787614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2442080.1"
                     /translation="MKMILNKGHRIRASDKNLVYHFSIGTLLFVFIAVILLLNMKQLM
                     RTDWEHFSLLDNGLTLSTYNFITLLIATGVCALVAFLYYRFCYDSFKKLLHRQKLARM
                     ILENKWYEADTVQDSGFFTDLQSRSREKIIWFPKIYYQMEKGLLHIRCEITLGKYQDQ
                     LLRLEDKLESGLYCELTDKTLHDGYIEYTMLYDMIANRITIDEVKAENGCLRLMKNLV
                     WEYDALPHALIAGGTGGGKTYFLLTLIEALLHTNAVLYILDPKNADLADLGTVMGNVY
                     HTKEEMIDCVNAFYEGMVQRSEEMKRHPDYKTGENYAYLGLPPCFLIFDEYVAFFEML
                     GTKESVSLLSQLKKIVMLGRQAGYFLIVACQRPDAKYFSDGIRDNFNFRVGLGRISEL
                     GYGMLFSSDVKKQFFQKRIKGRGYCDVGTSVISEFYTPLVPKGHDFLQTIGSLAYARQ
                     DGTATCEAKGDGTD"
     gene            complement(14071..14556)
                     /locus_tag="PC512_002342"
     CDS             complement(14071..14556)
                     /locus_tag="PC512_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006776881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442081.1"
                     /translation="MAKEKGSFKEFLSAIAPEHQAFVEKLNTKLIEQGCDLVIKEAKS
                     GYTASYQLEKKTVMNWVFRKTGVFARIYGDNAGKYEDIIASLPADMQKKMTTSRDCKR
                     LIDPNACSDTCVKGFVYALNGDTHKKCRNDGMLFVLTNETAEHIAGLVCAEVNVRKSA
                     L"
     gene            complement(14654..15037)
                     /locus_tag="PC512_002343"
     CDS             complement(14654..15037)
                     /locus_tag="PC512_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014080829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HDF2442082.1"
                     /translation="MRLANGIVLDKEKTFGVLKFSALRHEVRAENDDGSTSEEITRRT
                     YDLKCSVQERMIQVSIPADIPVKDYPYNAEVELVNPVADTVANASYRGVNVDWYIKAD
                     DIILKNKGGQVGNPQNHAPQGQPKK"
     gene            complement(15052..15378)
                     /locus_tag="PC512_002344"
     CDS             complement(15052..15378)
                     /locus_tag="PC512_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005337695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HDF2442083.1"
                     /translation="MELKYVVPNMAQTFGNLEFAGENKIEQQRINGRFTPVSRSYNLY
                     SDVQRADDIIVTIPAKAGEKHFKPEQRVKLINPKITADGKAVKGRGFTNYILTADDML
                     PAEESK"
     gene            complement(15614..18658)
                     /locus_tag="PC512_002345"
     CDS             complement(15614..18658)
                     /locus_tag="PC512_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HDF2442084.1"
                     /translation="MKKILKRLCTGVLAFATVVTALPTTLVHAESKQYWTESEERVGI
                     VEKVMNDGSIGSTFNEGHLTVEGEDAYCIDINTDFKNGYKTRADASSRMSADQISDVA
                     LSIEYVKQYTDNHNGISKNHAYLLRQLVVWQRLSVHLGWQCDNVRASYDEIPKATQDE
                     VFAGAKAFVKENKGRYECGGYIYSGEGQELGQFWAKLNVGNAKLQKTSNNTSITNGNG
                     NYSIAGATYGVFSDKDCTKQIATLTTDDSGNTEVAEVKATTVYIKELSAPLGYKVDTT
                     VYSLKVEAGKTATLKVSDTPKVTDTLIELFKIDMETQKANPQGNASLEGAEFTWKYYA
                     GFYNKDNLPAEATRTWVTKTTAETDSNGTTHYITKLADAYKVSGDSFYMQDGKAFLPL
                     GTLTVEETKSPTGYLLDGAYMQANGSEEQIKALYLTQITEDGDLAVLTGSNQFSVSDK
                     VIRGGVKIQKRDLETKDTKPQGSATLKDTAFDIISLNDNAVLVEGKIYKKNEVVKTIH
                     TDIEGIASTSADLLPYGNFRIVEKQAPNGYLTDGAKPIDFTITENGKIVDLTDEAHSI
                     YNQIKRGDIEGVKIGAGTHKRLADVPFRITSKTTGESHVVVTDDNGQFSTSSKWASHK
                     HNTNAGKTSEDGVWFGTSEPDDSKGALPYDTYIIEELRSDSNKGMELIPPFEIVVSRN
                     NLVIDLGTLTDEYEKEITIHTTATSKDGEKTILAGKEVTIVDTVKLDGLTKGTKYQLK
                     GWQMLKEENAEIIIDGKRVESDYTFVADDEEMKVEISYTFNASELGGKNLVTFEELYD
                     LSNPDEPMKVAEHKDIEDDGQTVLITERIIKIHTTATDKDGNKELEAGKDVTIIDTVT
                     LEGLEVGTKYKLVGWQMLKEENAELLINGKRVESDYTFIADSETMKVEVTFTFDATSL
                     DGKQLVTFEELYDLSNPNEPKKVTEHKDIEDEGQTITFKEKPEVPEKPETPTTPEKPS
                     RPTDSPKTGDNTNVMAFLVMLLTSAGGLAGTYLYKRRKMKKS"
     gene            19186..20193
                     /gene="asrA"
                     /locus_tag="PC512_002346"
     CDS             19186..20193
                     /gene="asrA"
                     /locus_tag="PC512_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit AsrA"
                     /protein_id="HDF2442085.1"
                     /translation="MKLKLDSSKFNEGLNYLKKDYKIFAPVLIPFKGTFSDTDVIRYK
                     EVNAFEEMEFAKKANFSPKDVVLPINQVLFYFTEKEFKESDLDNKKILIFLRACDING
                     IKRLDEIYLNNGEEKDYFYKNIRDKVKFALVGCKESFRNCFCVSMDSNKTDNYSIGLN
                     IEGDTLYLDIKDSEFEVFNGEATEFNVDYVTDNLISVDVPENIDSNEMIGNSIWDEYD
                     TRCIGCGRCNFVCPTCSCFTMQDIFYKENENVGERRRVWASCQVDGYTDIAGGNSFRK
                     KQGERMRFKTMHKIHDFKKRFGYHMCVGCGRCDDACPQYISFSKCIEKINDLVISKEE
                     V"
     gene            20194..20985
                     /gene="asrB"
                     /locus_tag="PC512_002347"
     CDS             20194..20985
                     /gene="asrB"
                     /locus_tag="PC512_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit AsrB"
                     /protein_id="HDF2442086.1"
                     /translation="MNPYIPVSAKILDIVKHTDKEWTFRVNCNTKGVLPGKFYEISIP
                     KYGESPISVSGYGEDYIDFTIRNVGKVTSELFNYKEGDSFFIRGPYGNGFDVSLYEGR
                     EIVVVAGGSALAPVRGIVEYFYNNKEKCEKFKLIVGFKSPKDILFADDLKRWSKKLDI
                     LVTVDGAEEGYSGNVGLVTKYIPELDMKDINNTSIVVVGPPMMMKFTVEEFLKRDLDE
                     KNIWVSYERKMCCGIGKCGHCKMDDTYICLDGPVFDYSYAKNLID"
     gene            20998..21969
                     /gene="asrC"
                     /locus_tag="PC512_002348"
     CDS             20998..21969
                     /gene="asrC"
                     /locus_tag="PC512_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite reductase subunit C"
                     /protein_id="HDF2442087.1"
                     /translation="MIRDLNTKKVMKNAYRITKTKYETSLRVRVPGGLIDPESLAVVS
                     KIASEYGNGQVHITTRQGFEILGINMEDMEEINKIIQPVIEKMNINQSEKNAGYPAAG
                     TRNIAACIGNKVCPKAQYNTTEFAKRIEKAIFPNDLHFKVALTGCPNDCIKARMNDFG
                     IIGMALPIYEKDRCVNCGACVKKCSKISVGALKTENNKVVRDKDKCIGCGECVLNCPT
                     NAWTRDEKKYYRLAIMGRTGKKNPRLAEDFLLWVDEDSIIKIILNTYRYVEKYIDKDA
                     PGGKEHIGYIIDRTGFMEFKKWALEGVELPEITKMYENIYWSGIKYL"
     gene            22026..22802
                     /locus_tag="PC512_002349"
     CDS             22026..22802
                     /locus_tag="PC512_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HDF2442088.1"
                     /translation="MHKETLDKLTNAAINKINLLNTSKVKYLVSSAFAGLYVGIGILL
                     IFTIGGLLTDAGSPMTKIVMGLSFAIALSLVIMTGTELFTGNNMVMSAGMLNKGVSIK
                     DTSKIWAYSWVGNLIGALVLGIIFVGTGLVDKGPVAEFFANTAASKASMPFTALFFRG
                     ILCNILVCVSVLCSFRTNSDTAKIIMIFLCLFAFITSGFEHSVANMTIYSVSLFSPTI
                     STVTIGGAIYNLVAVTLGNIVGGALFMGLGTYILGKEKLN"
     gene            23073..25091
                     /locus_tag="PC512_002350"
     CDS             23073..25091
                     /locus_tag="PC512_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDF2442089.1"
                     /translation="MTKKLVISKTKLFIFIIAFISIFIYLFGSKNTLIGVGIVTAMLT
                     LLERDLTISPIKNLLKYLAINIILGILSFFAVQNMYLGVLLNFIALFIIGYVFSYDLK
                     RAVYVPFGLMYIFMVSIPVGKSEFPMRLSALAVGAVIIMIAQFVMNRNRMKNVGDKEL
                     ISICDELLEKISLLKNTINDDSSIIKSSMRKIDSCNYRINSISKNLKMVIFDNRKDDF
                     YISIRGIDIMNILFSLERISLILERYKKDSKEFEDEDIKNILEESSINSKSDVLVVAT
                     KEINYIKMCLENKDTITDKEILGFRDYVIAQDTKNINLKEIYSVLENLYEFLVDYKKV
                     KSRDEKKAERKSKIPHEFKRLSIYKKNFNLNSIRFSYAVKIALATAVAGFIMDYFHLR
                     DGRWIMLTVFSLTQPYAENCIQRSRKRIEGTFIGAVIFIVLFSIIKDSTLRSLIVLLA
                     GYINSYVVDYRKLMVCVTVSALGSAVVMGDPNVLTISRISYVALGAIIALIVNKFILP
                     YDAKTGYQHVIEMYKGIVKNIIDEVNKSIENVADVYYIKNLLLIPSLIEDRLMLINAI
                     YKDKHQEDFLENQKLLISNMYNLYINVNKNKIKDEDVEKILRDTNYISNYNVDKYDEG
                     RSVILESIVNTKSLGDKIICLNLLQTLNGVKEMYRISNITKVSIKEAA"
     gene            25306..26163
                     /locus_tag="PC512_002351"
     CDS             25306..26163
                     /locus_tag="PC512_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2442090.1"
                     /translation="MSKDVKVKRNKKYDTFSITMELERPLLYDEVENKDDKNNNRKFN
                     IKNKIFKGIGILFVLILLGFFIWINKTYEPQKLAKEALVSNSKVEVTVNENISFTPKG
                     RKVSKGLILYPGAKVEIESYAPLARKIAESGYEVVIVKMPLNLAILGTNKAQKVMDSY
                     NNIEHWVIGGHSLGGVAASNFARDNKLIEGVVFLASYPMGDELKELGKKVISIWGSKD
                     GVVNFKSLVESKQKLPDDTTYVEIEGGNHAQFGDYGKQKGDNDAIISQEKQLNITANS
                     IIKFLKNIS"
     gene            26260..27129
                     /locus_tag="PC512_002352"
     CDS             26260..27129
                     /locus_tag="PC512_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF2442091.1"
                     /translation="MEYDMPLYRPPSEAYSLIIQVTLGCSHNKCTFCSMYKSKKFKIK
                     PLEVIKNEIDIFRRYYKHVERIFLADGDALIIPMEKLRDIILYIKEVFPECERITMYG
                     SPKSIEKKSDDELKELRKLGVKMIYLGLESGSNEVLEDIKKGFSSEQLIKVGRKVKKS
                     GIKLSATVIAGLGGTKKTHQHAVDTGKMLGAISPDYVGVLSLMVEPNTELYDLLKAGE
                     FTILEDKAVLQEIKEMIKNIDANEKIVFRSNHASNYANLKGVLPDDKQRLIDEIDYYL
                     SNQKLKREEYRRL"
BASE COUNT         8310 a         5033 c         5026 g         8997 t
ORIGIN      
        1 attcccacat gggtaacata cgaaccagcg ttataggttg aatggaaaaa gaccaactcc
       61 ccagcttttg cctgcgataa agggatatgc tgggttgcgt catattgcat ttgtgccgtt
      121 ctcggtaaag agataccagc ttttccataa caccattgcg tcagtcccga acagtcaaag
      181 gaagtgttgg gattgctacc gccatacaca tatttccagc cttgatattt caacgcttca
      241 ttcattacct tttgtgccag ttctcccgat acctgcggaa cagttaaata ctgattgact
      301 aattccacat aaaacatatt tccatagcca taccgccagc ccccattttt cgcaacggct
      361 atcgggttgg tgtaggttac ttttttaccg ccagatttct cacgggcaaa gctctctgca
      421 aggttaaaag tatgtttctt tccttttcct gccacatatc ccacatagcc accgccatag
      481 ttataggact gtatcgccac attcaaatca tttattcctt gatttttgca ggaagaaagc
      541 agggacgcaa aatatttaca cccctgcttg attgagcttt ctgtatctaa cgagttgggc
      601 ggtaaaccaa gactttctga actctgcatg acatcttttg ccgtaccgcc actttctact
      661 tgaatgatag ccagtaacac attcacatac tcagaaatac cgtattcttt agcgtacttt
      721 tccaccatag gctgatgttt caagacttct gcggataaat tcatacccgt aatgcccgaa
      781 gaaaagttgc tgttctcgtc gtcgctgtcc gcactcatca gtaccccaaa gaaaaggact
      841 atggaaaaga ggataggaaa cagactgcca atgatagcga tatgtttcaa tttcattttt
      901 tcttctgtcc tttcttcgtt acaaggttac ggttcttttc agtatgttct gttgtacgct
      961 ttgcttgttc aactgtttgt gcctttgtgg tacgttctgc tttgtaattc tggtgtgttt
     1021 catgcgatac cactttttct acatttttac tatgtactgt ctgtgccgat tgtggaattt
     1081 ttccgtcaga tgtacccgaa gataagggac gttctttcac actatttgtt ttgactggct
     1141 cgcctgcttt ggaagttgaa gttgtagcag gacgtttgac ttcctgtgtt ttctcaacat
     1201 ttgtttttgg aatggctgaa gctgtgactg gtcgctcatg gggacgggta gctcccgttg
     1261 tcgctgatcc gtccgtcttt cgtgcctgcc ttgcttcttg tgctttttga agttccatac
     1321 gcttgtcagc gatattcttc ttatgctgtt cctgcttttc caagcgtccc gactgtctgg
     1381 attgttgttc ctgcaccatg ccacgcttga agtccgatac acttgttttt gctttttcct
     1441 ttgcggaatg gacggcataa gcggtctgtg tcggtatatc cttgaccgtt tctttcatag
     1501 cgtttgcctt gtctttgacc ttattcttcg tatctaagac agcacccacc tttgaaccag
     1561 cacgttgtcc catgctggaa gatgtattcc ctcggttgtc ttttgctgaa ttattccttg
     1621 ttgtccttgc attagaaacc gtactgccag ccaccgcacc agcaacaccg ccagcggtaa
     1681 cagcaccagc aagccgtctt tccatacgcc tagccctatg tgccatataa agatacggtc
     1741 tgcggaaaat tcttcgtccc atgctttgac tgtcgttagc gttcaaagag aacatactca
     1801 ttaaatcgcc taacttcatg tagataccag cgaaacacac tatctgcaag aacgccacca
     1861 taaagaacgg gtagtctgtg gaaatgttat aaaacatact ggaaatgcta aatgccaccg
     1921 ttacaatgag cgtaattcct gcccttgtca ttatggtatt aaataccctc acgattgcct
     1981 gctttgccat gctttcatag ctcggtatca tggatagtaa aaagctgata ggtaaaaaca
     2041 tggcgaagat aataaaaagt atctggctga acaacatcat acccgtaagc aagaatacaa
     2101 atatcgtgat acctaagttg aagaacaaga ggaagaacac catacctaaa cggtttacga
     2161 cttgcggtat cgtcagattg ttgttgtcgt tactttcgat ttctgttttc acgacttcct
     2221 ctctggtttt gccgtcctcg ttctctgggc ttgccgatac aagagcttct acacggtctg
     2281 tcccgatttc ctctgcgttg ctgttcccaa actgtaagag tagccacggc tgttccactt
     2341 gaatagagaa taggctgtcc cttatcaagt ccacgctgtc cttgccctcg ctgtcagagt
     2401 ttgggagcat gatttttgtt cccaagtcca aagaagcggt actgatgtcg cttgaaaatt
     2461 catttatctt tttgatgtag tcgggagcat aggcaataaa tgaagccgac aaaataaaca
     2521 ccacaacaaa gttgataacg gcgtgaagtg ccttgctggt ttctctttta atcagtcccg
     2581 tataggcaac atatagtccc accactaaga taatgagaag caggaaaccg acatagaagc
     2641 cagaggttga aaaaccgctt gaggtaacgc ctgcaagggt ctgtatgctc tgcccgatac
     2701 tgtctgccat atcattgatg aagtccagct tgtaggcttc ctgcactaca tagcccgtgg
     2761 cattacttaa atataaactg atagtccaga caaaattagt gatacagtac aaaccatatt
     2821 gtactgattt tccaatcccg tccagccagt tccacggcaa ccaagcccag ctattatcca
     2881 catagaagtc aagctgatag ttggaaagcg gatatttgga atatagattt tctgcgttta
     2941 tcgtatcgtc cacaagcccc gtcgcatgag ccaccgtccc cagaagtgaa agcaggataa
     3001 gggagagtgc caccacgaac agagccattt tgagaaagtg gaaaatcttc ttttttgtga
     3061 acgcactctg tatcctttct ttcatcactc cacctcattt ctctgtatag gcggtctggt
     3121 atcaaaggcg tgtagcagtt cttcaaagac ggggtgtatc tgtaccacgc cgacacgccc
     3181 gtataagtcc tgcaacaagc attgtccgtt ctccaaatca cgaagtcgct tctgattgtt
     3241 ttcgtcctct ttgtcgatac cgaaaaattc taaagtctgt tttatctcgt tgatgtcagt
     3301 agaacggaaa gcgaatttta agccgatatt gtttttcaga ctttcctttg acacgtcccc
     3361 agaagattgc gtaacgaaat acacacctgc ctgcatagct cgtccagcac gcaccagctt
     3421 gttagataaa atttcgcctt gtgccacatt taagaacgcc cacgcttcat caaggtctac
     3481 gattttgaag atagagcggt cgctgtggat aaaatctaag gcaaaggtac taatcacaat
     3541 cagcatggaa accgatagta attcaatggt cgtgtattcc tcaaaagtcg tgtccttatc
     3601 tggcagtaca aggtcggcta cttgaatgat attgagctga ttatctaaac tgatagcatt
     3661 ttccaccgtt ccgtctgaaa acagaagatg tgcaaaatca tagtctgtaa agctgtcgat
     3721 atggtctgcg atattgcgtg aaattgcggt atcttcacag cgtaactcgt ctatcacatg
     3781 aagcaagccc cttgtttcac tctgggtaac agaacgcacc gccttacgaa gtacggggaa
     3841 tttttcgccg tccctagagg aaataccagt taaaaaggtt agtatgtcga ttgccagact
     3901 ttcagcgtct ttcacattct tcataatcac aaacgggtca agaagccctg cgttgtcctt
     3961 gtcgcttgtt aggtttacga tattgatttc atgggcgatt tctggaagtg tttctttcca
     4021 gtttccacgc tctgattttg ggtctaagat aaccgcttga ccgccaaaca aaacagaata
     4081 gtacacaagc aggttattac agaatgactt cccaccgcca agcgaaccaa caaaagcaga
     4141 agcaagggca tttgtaactg taccttttac gccttgactg gcaagggacg gttgcagata
     4201 tacatttctt cccgtatcaa cggaatagcc catatagata cccgtgtttt cccctaactg
     4261 ctgtgtcgca ccaaaaccaa gcccagctaa gaagtctgat tttacatact gcacataatc
     4321 attgatatat cgcttgctgg ctggtagaaa ttcagaatga agccccagca tatccccagc
     4381 aggacgtact aacttcacat tcaaatcgtc ataaaaatct ttgacttcat cacaacggcg
     4441 tttcagttcg tccaaatcat cagcagacac acggataaca taagagagct tatacatact
     4501 ttcttttgtc tggtctaaat cggtttccag ctcgtccacg ctgtctaaag cgtctactac
     4561 atttgagctg gtttcacttc cagcttgata agcgtgatta tcaaggtctt tcagttcctt
     4621 tttcttgttg cggacggtcg ttaatgcttt tcggttttcc acgatttcta cattcatgct
     4681 cgtatcaacg ggaaaggtaa attgctgttg ctggaaatag aagatttcac tagacggaaa
     4741 atcaagctcg cctacaatcg cattgacggt aaaataggac acataacttt ccttgtcctc
     4801 atgttccaat cgtaaatatc gctggctttc ctcaatcaca caccttgtcg ggcggataag
     4861 gtcgtaatac ttgataagtg tttctttctt atactttttc tttggtagct ggtgctcata
     4921 atcttcatag gcgataccgt ccctgccgta aagatgttcc ataagatacc caaagtcatt
     4981 gatttccaga cggcgaacct taaagcgacg ggagatttta ttttccagta acttttccat
     5041 tttcatgtaa cggttgattt catcattcgg catggaaaca aagtcgttca tcagcgtgtg
     5101 gttcacttca tggagaaact ctttgaacgt cagccacgcc gattttttaa ggttcttcag
     5161 attgagctgt tcttccgtaa ccatgagttt aaagccaaga aaaaagcggt agtccacttg
     5221 attgtcccca atcattgata ctaacgcttc ggtctgttcg tctatcttct ggtaagcgac
     5281 ttcctttaat ttccccgtaa ccaatctttt tgactgctcc tgcatacttc ttatagagct
     5341 ttccgtggca atctgcaaag catgaatttt accctcacgg gactgtgcga ttagctgtcg
     5401 gaaactgtca tgcacgataa atttctgttc tgcggataag aaagaatagt tatacggtat
     5461 cagctcatag taggcgaaca cctcattgtc cttgttccag acaaggttgt tgtcaatata
     5521 tttaatcggg aacataactc acactcctta ctgccgtgat tgtttcgttg aatatttctt
     5581 tttgcagttt tacggctttt cctgcataag tgattttcgg tcgcaacgca taggttatct
     5641 gtgatttcaa aaagctgtat ggcttctttc cgtcaaaggt tttctgcgac ataaaccaag
     5701 tgaggaaagc aggaataccg aagtatttta aaaatgctcc ctcaatcatg gaaagtgggg
     5761 gcatatcccc aaacagaatg atgataaatt ctgtaatcac aaaccatgta atctgtgtaa
     5821 aggtaacggg aaagggcaag ttaaagtcat tgattgcata caagactttt tctacattcc
     5881 agatacccgt gtagcttcta atctttttca agttctttca actcctctca taagtttcta
     5941 aatggaaaag gacagccctg tttcagactg tcccttaaag agaaatacgc cgtcagtagc
     6001 aacaatgctt gtcgctgatc ttccagcgtt aatatggtat ctcgcacatt cctcggcttg
     6061 ttgcaatgaa gcaaccgccc atatccaaat ctcgcccgta tgcttcatag tcaatatagt
     6121 tctgcaagct agggggaata tcgccaagtg cctgcaattc atctatgtag taataggcaa
     6181 catctgtcat ggtttcacag tcgggataat agtaaatatc gtccttgtgt tccacgactt
     6241 cctccagcgt cccataatga ccaataaatt cgtccaaaca atccacgata tagtcgggaa
     6301 gttcctctat catttcatac atttcattga gttcatcaat ggaaacatac tccccaatct
     6361 caatcgggaa gttatcggta tcatggattg cgtattcttc atactgttca ttcaagccga
     6421 ttttttcttt cacatcttcc tcgtcaatag ggaaagtaaa ccaagcaccg actaaatagc
     6481 cctcattata cttgccaaga ttagcgatat aaactgccat atcatcaatc atacttactc
     6541 tggcaattca aagataccgt gttccgttac taaaaatttc ccgtgttcct gcaagtgtga
     6601 agcataggtt tcaaagtcaa aatagtattc ttgacagtcc tcggataaat gtttgaatgt
     6661 agggtcattc atcagctttt gccttgcaac atcaatcatg cttttacagt cgggataaag
     6721 cgtaattaca ttcctgcaaa tataaagtgc ttctaaattt tcatacaccg tatgaagcat
     6781 tgtatattct tcctgcatat cgcttgaaag ctggcgatac atataatcta attcattgag
     6841 ctggtacacg cttgtatgct catggacttc atcagcataa ggcaacaatt tttcaataat
     6901 gcggtaatct tgactttctg tactgacacc taacttttct tcaaactcgg caacctctat
     6961 cggcaggtcg aaccagtatg atgttgtttc ttcgccagtt gttcttttcg tttccaccag
     7021 tacccttgtt tcctgcattg ttcctcacgt cctttctgtt gtttcatcac atcttttaaa
     7081 gtctggcatg acataccaaa cacatatttt gaaaaatctt ctaactgttt ttcttcatag
     7141 tcggcaaggt tcagttgctt catttcatgc cacaccttac gcttgtaaga gggcaggtct
     7201 gaaatgtttt cacaaccaac ttttgcctgc atatctctaa aaatatcgtt cattacatca
     7261 ctccaatctg aaatttaggt aagaaaaaag cagtcaatcc taagactaac tgctttgtgt
     7321 gtatggatat gaagttgtca aactgggatt tatctggcag acttgtttat ccactcatca
     7381 agaaatttca tttgttcttc cgtgtgaaac caatgctctc cgtttctcat aacagtaagt
     7441 gttgcattag tttgttttgt aaattcagat atagttgcat aagaagtcaa gttatctttc
     7501 tcaccaaata aaatatttgt tggaattttc catgtagttg gattttcttt tacataacag
     7561 agatattccc atgagagtgt ttctccaaaa gttgttttaa tttctttttt atctcgaagt
     7621 tcatcttctg taacatttgc ccaatacatc atatctgcaa tcagtttttc catattcaca
     7681 ataggtgaaa taaaatatgc tttttctatt tgcttatctg ataaggcgtt catagcgaaa
     7741 taggcaccta tgctatttgc aactatttga acagatttgt aatgtttgca aatcaaatca
     7801 aaaagtgatg gaaattcttc ttttgcttcc catggatatt gtgcagtata gttgagtcca
     7861 accacatcac aatcactaaa aagaggtttg taatgtgaag actcctctgc atttccacct
     7921 ttaccatgta tataaataac tactttatcc ataatagttg tcctcctcaa cttcaaattt
     7981 gtcgctttct tcatatccac attatatcat tctcatatca gcaccacaat aaaattttac
     8041 gcaccgataa tcttattgaa cagctctaac agtacgtctt tcacaccgcc agcattgaat
     8101 accaatccaa cggcaacaag ggcaactacc aagaagccga taagtttaga aaactcacgt
     8161 ttgaacccta agtagatacc aataaccaca atcgccataa gcactaagct ctgggcgttg
     8221 cttaaaaacc atgtgtatat ggataggtaa gttcctgata ttataaatat ctcaaacttt
     8281 tccccccatt cacacggagc gtgcgacttt caacgcactc cgcgttccat cgtgtttata
     8341 ttgaaaagta tttatgtagt agacctatat caagtttaat tcttgattgc cagctaatac
     8401 tctatattta tttagtctta tgagctggac tttatttagc ttcaatagag ctatatattt
     8461 ttgtattgtt tcttctgttt tagcgtgtat tagacggtgt accgcctctt ttaccaaaat
     8521 atgattttta taatcgtcat ttccaccagc tccagttggt acaatatgat gacaatgtat
     8581 ttcattagct tgttgaaatt cttccagagt tatagcacat tttccatgtt gagcagaaaa
     8641 tagcgaaatt cgattgtctg cgtattctat tgtgcgattt tccaaagata atttcattaa
     8701 ctggtacatc agtaatttat caacacttag attggtgtgg ataaattttc ttccctctag
     8761 agtgtagcaa ttcgctaaat acacctttgc cattggtttt ctgtgttgga tatatccaac
     8821 agggaaaata ggttcgccct cgccagcaac ataccggagc attttagatt taccatatct
     8881 tgttgcctcc tttgtcgtaa gttgtctgcc tgtttttctc aatctgcccc ttttgtttgt
     8941 acctaatctg ttagtgaaga tagccattac agctctattc agtttcatac aatccagatt
     9001 tacattcgtt gcaatctgat aataattttg catacctaat accattgaat tataaagtct
     9061 tgtttcttct aattccgttt tcccttttga gggagaagca attttctttg cctgtgatac
     9121 cagcttgtct ttttggtttt tgaattgttt atcacttata tgtgatttaa caactaactt
     9181 ctttcttctc ggtatcattt taatcttgaa accaagaaag tcggagtatc tttttctaac
     9241 atttacaatt cttgtttttt cttgtgatac ttccaatttt aatcgttgtt caatccattg
     9301 agtgattgct attttggctt tttcagcact ttccttgtag cggcagaaaa ctctaaaatc
     9361 atctgcataa cgaaccatat acatttcctt taactttgtt ttcttcattt ctttgtaagc
     9421 gttgctttta catgggctac cgcttttatt gatatgaacc acatagtttt ttgtaacagg
     9481 attttcctgc cattggcttt ctacccaatg gtctaactca ttaagaacaa tgtttgctag
     9541 tagtggggat attattcccc cttgcggagt tcctttctct ggatatgtta ttgtaccgtt
     9601 agtcattttg attggagctt ttaatatcct ttttaaaatg aatatcaagt gcttgtcccg
     9661 tattcccata gcccatatct gttttatcag cttggaatgg ttcacgttgt caaagaaacc
     9721 cttaatatca aattcaatca cataatgtag ctggctgatt tgtaggcggt tataggttgc
     9781 ttttattgca ttttcaactg acctattagg tctgaaacca tagctgtttt cactaaattt
     9841 agcttcgcag attggttcta atacttgttt tatacattgt tgtataagcc tgtcccacat
     9901 acaaggaata cctagaggtc tggttttacc atttggtttt ggtatttctt ttcgcctcac
     9961 tggcttaggt cgatacccat gtggactgcc tgcaacaatg tatcttactt ttttgacaac
    10021 tgtttctgct ggcaatttgc caatatcttt aattattgta ccgtctgttc ctgctgtttt
    10081 actgcctgca tttgctttga tatttcgata tgccagtaat atattttctc tcgataggat
    10141 aatatccata agatgagtga aaatatctcc attcttactt ttggcatata aatcatcaaa
    10201 ggtgttttgc atttcgtaat attcagcgtg tcttaaatct tctacacaca atgtttcatt
    10261 tttattttta ggcataaggc ttcactcctt tgcttgaaat tgagtgagct tttttatctt
    10321 actcgtaatc cttattgaaa caacataata cttttctaat atatacacga cttgagggca
    10381 ttcctccatt ctcattacaa gaatttctta ggttcgccct ctgcttttca gcattagttc
    10441 aactgcttat tgttcttcgt cagtttattc tcttgatgag aacccaatac ctttcctcgt
    10501 tccgataatc ttatctatac atatatatcc ttaggtcact agctataagc ctgctggctt
    10561 gataccgcct gtaacgttat atggcatttc ataacctata ttcttacttt gccacaccag
    10621 ctacgatttc tcgtaccttt gcatttctac aaagttcaaa tttagacccg tacattcgct
    10681 gtttcgtcag ttccttatag aacattctaa ccatagatat tttatagacc cccgacctgt
    10741 tggatacgct acccgcctct ggatagtttt cgatagaaga tatatgttca tcaactatta
    10801 cggtatcttt cagccgtctt taccgagctt caaacattct gagtttcctc atacaatgct
    10861 tgtcggaggc tcagggcagg cgtttcagag cgttacttca tcattccacc tgtcagatta
    10921 tcagttctcc taataaccaa actttttcgt tcttttatta gtgccttagc ttttcactaa
    10981 ggaacgagtc gcacataaat tttgtccgaa attcatttaa ttgtcctctc tttctttgat
    11041 ttcttccata catctgtcag cttctttgcc gacagttaaa atgcacatca agactacacc
    11101 gatacccatt ccaaatgata ccagcaataa gtctttcaat aattcccaca ttttttcatc
    11161 actcctttac gttggcaacc atttcttcaa ccgtggctgt ctgttgcttg attatctggt
    11221 agtgtcgttc ggtcagtttt gcctgctttt caatcgtttc cagatactcc gtctgattgt
    11281 ccttgtctat ctgcttcaac atcttcaagg tcggtgcaac ctgcctttgt agccagttga
    11341 gtgtacgctc cagcgtgtaa ggttctggct gtgttgtcag ctttacgggc ggtcgcccct
    11401 cgccaatgaa ccaagcccag cgtacattgg ttttccagtc gctttttcgc ttgtctggtt
    11461 ctttatcagc gaagcggata tattgattga taatagaaaa tgctgtcagt tctgcgtcat
    11521 aatgtgtcag cagttccaca acagcataat aggcacgttc atttttcaaa cgtatctcaa
    11581 atctattttt tatggggact tcctcaatcg gtatgccaag tttggcgtac tgttcgtaat
    11641 tcttttcata acagcagaag tacacttcac ttgaaaatga accaatatac agcgtgtgtc
    11701 ccataccgta tttatccgtt tcattatgct ttaccagctc tccagaacca tagcttttga
    11761 aagaacggaa tttagaaata cattcctcat tctcgcattt tcgtatcagc tctggaatat
    11821 caagtaagcc cgttcggtca ttgattgcca aatcaagacg cttcattaca ccgccctcaa
    11881 ccaatgcgtc cgtgaagaag tcataccaac ttcgctcttg tgccagcaga tagctttcaa
    11941 actggcgaca gcctttgcct ttcagttcca gcaggacacc tttttcttcg tcctgcgata
    12001 catacacaaa cacatctccg atatggtaat gctcggtgta tttgtaatgt ccgtaatctt
    12061 cgtgaagcat atagccgatg ttgagcttca atatatcctt gatgatatgc tttatatcca
    12121 ttgtgggaaa acggatacgc acataatcaa acagcaggaa catgggattg ttgggattga
    12181 atttttccac cgcttctaaa agcgtatgtt tcatgtcctc ggtcagcgtt acctttcctg
    12241 cttcgatacg gctcaaatgt tcacggctga tatttgccat gattgcaagc cttgtctgcg
    12301 atacgccgta tgcacagcgt ttttctttca aggcggttaa aaaatcagtt tcattcagtt
    12361 gtcatacccc caatcgtgat aattttgtga tattgtgata atttcaaggc tttatcacaa
    12421 aaggcgaaat gtacgaaaaa cccttatttc atgcggtctt gcaaaggttt ttgtggaagt
    12481 ttccgccgta attgtgcccc tctgttagat aatgaggggc ttgtatctgc tggcgtggct
    12541 aacgccacac cagcaacggc tagtccgtgc cgtcgccttt cgcttcgcac gtcgccgtcc
    12601 cgtcctgcct tgcgtatgca agtgagccta tggtctgcaa aaaatcatgt ccttttggaa
    12661 ctaagggtgt gtaaaattca cttatgacgc ttgttcccac atcacaatag ccacgtccct
    12721 tgatacgctt ctggaaaaac tgttttttca catcagaact gaacagcata ccgtaaccta
    12781 attcgctgat acgccccaag ccaacacgga aattaaaatt atctctgata ccgtccgaga
    12841 aatattttgc gtctggacgc tggcaggcaa caataaggaa atatcctgct tgtcgtccta
    12901 acatgacgat tttctttagc tggctaagta ggctcacact ttcttttgtc cccagcattt
    12961 caaaaaacgc cacatattca tcaaagataa gaaagcaggg cggtaaacca agataggcat
    13021 agttttcgcc cgttttatag tctgggtgtc gcttcatttc ttcgcttctt tgtaccatgc
    13081 cctcataaaa ggcattgaca caatcaatca tttcttcttt ggtgtgatac acatttccca
    13141 ttaccgtacc taaatctgca aggtcagcgt tcttcgggtc taatatgtaa agaacagcgt
    13201 tcgtatgtaa cagagcttca ataagcgtca gcagaaaata cgttttaccg ccaccagtcc
    13261 caccagcaat cagagcgtga gggagtgcgt catattccca tacaagattt ttcatcagcc
    13321 taagacagcc gttttctgct ttcacttcat caatggtaat gcggttcgct atcatatcat
    13381 aaagcatggt gtattcgata taaccgtcat gtaacgtctt gtcggtcagc tcacaataca
    13441 agccactttc caatttatcc tctaaccgta agagctggtc ttgatatttt cctaatgtaa
    13501 tttcacagcg gatatgaagc agtccttttt ccatttgata ataaatcttt ggaaaccaga
    13561 tgattttttc ccttgatctg ctttgcaggt cagtaaaaaa accgctgtct tgtacggtgt
    13621 ctgcttcata ccacttgttt tccagtatca ttcgtgccag cttttgacgg tgcaggagct
    13681 tcttgaaact gtcataacag aagcggtaat acagaaaagc gaccaatgca caaacaccag
    13741 tcgctatcag tagggttatg aagttgtaag tggaaagcgt caaaccgttg tctaataagc
    13801 tgaaatgctc ccaatcggta cgcatgagct gtttcatatt cagtagcagg ataaccgcaa
    13861 tgaatacaaa cagaagcgtc cctatggaaa agtggtagac aaggttcttg tcgctggctc
    13921 tgatacggtg tcctttgttt aaaatcattt tcataaatca atcactcctt tctgggtacg
    13981 aaaaaagcag tcaatcctaa gactaactgc tttgtgtgta tggatatgaa gttgtcaaac
    14041 tgggatttat tgttcttaac ttttctgtcg ttataaagct gacttacgca cattaacctc
    14101 tgcacagacc agcccagcta tatgctccgc tgtttcattt gtcagtacaa agagcattcc
    14161 gtcattacgg cattttttat gtgtgtcgcc attcaaggca taaacaaaac cttttacaca
    14221 ggtatcacta caggcattag ggtcaatcag tctcttgcag tcacgagaag tagtcatttt
    14281 cttttgcata tcagcaggaa gcgaagcgat tatatcctca tactttccag cgttgtctcc
    14341 gtaaatccgt gcaaaaacac ctgtcttgcg aaacacccaa ttcattactg ttttcttctc
    14401 tagttggtat gaagcggtgt aaccgctttt tgcttccttt attacaaggt cacagccctg
    14461 ctcaataagt ttggtattaa gtttctcgac aaacgcttgg tgttctggcg cgattgccga
    14521 tagaaattct ttgaatgaac ctttttcttt tgccattatc tttttcctcc acaaatttca
    14581 atttatccgt ttcttcatac acatattata acagttgctt atatccgcta caatgaaaat
    14641 ctagtttgcc agcttatttc tttggttgcc cctgcggtgc atggttctgt ggattgccta
    14701 cttgaccgcc tttattcttc aagataatat cgtcagcctt gatataccag tccacattga
    14761 cacctcgata gctggcgttt gctaccgtat cggctacggg attgacaagc tctacctctg
    14821 cattatacgg atagtccttg acgggaatat cagcaggaat tgatacttgt atcatacgtt
    14881 cctgcacact acatttcaaa tcataggttc ttcgtgtgat ttcttcactt gttgaaccgt
    14941 cgtcattttc tgctcgcacc tcatgtctga gggcagagaa cttcaataca ccgaaagttt
    15001 tttccttgtc taatacaata ccgtttgcta atctcataat catttacccc cttacttgct
    15061 ttcctcggct ggcaacatat catcagccgt taagatatag tttgtgaacc ctcgtccttt
    15121 gaccgcttta ccgtctgcgg taatctttgg attgataagt tttactcgct gttctggttt
    15181 gaaatgcttt tcgcctgctt tcgctggaat ggttacgata atatcatcag ccctttgtac
    15241 gtcagagtac aagttgtagc ttcttgatac gggcgtaaag cgtccgttaa tgcgttgctg
    15301 ttcaatcttg ttttcgccag caaattccaa gtttccaaaa gtctgtgcca tgttcggcac
    15361 tacatatttt aattccatag tgttttacct cgtttctttc ttctttttta agtttgttga
    15421 ttgtgctttc ttattctggg aattagggaa ataccagtaa tcccccagat agtaaagggt
    15481 aaatcaatgc ttcgcaccct tgactatccg tgtgcttgca ggttgttggc agacaagcca
    15541 gaataagtaa acgtctgccg tttgacagct tcggcagaga gcgtgatttt tcttttctca
    15601 taccgttacc gccttatgat ttcttcattt tacggcgttt gtaaagatat gttccagcca
    15661 gtccaccagc agatgtaagc aacattacca gaaatgccat gacatttgtg ttgtcgcccg
    15721 ttttaggact gtctgttggt ctgctcggtt tttctggtgt tgttggcgtt tcgggtttct
    15781 ctgggacttc tggtttttcc ttaaaagtaa tcgtctgtcc ctcgtcctca atgtccttat
    15841 gctcagtaac ttttttcggc tcgtttggat tgcttaaatc atacaattct tcaaaagtta
    15901 caagctgttt gccgtcaaga gaagtagcgt caaaggtaaa ggtaacttcc actttcatag
    15961 tttcgctgtc agcgataaac gtataatcac tttccacacg ttttccattt ataagaagct
    16021 ctgcattttc ttctttcaac atctgccagc ccacaagttt atactttgta ccaacttcca
    16081 agccctctaa ggttacagta tcaatgattg ttacgtcttt tcctgcttca agctctttgt
    16141 taccgtcctt atcggtagca gttgtatgta ttttgatgat acgttctgta ataagtaccg
    16201 tctgcccgtc gtcctcaata tctttatgct ccgcaacttt catgggttcg tctggattgc
    16261 ttaagtcgta taattcctcg aatgttacca gatttttacc gccaagctcg gacgcattga
    16321 atgtataaga aatttccact ttcatttctt catcatcagc aacaaaggta taatcgcttt
    16381 ctacacgttt cccgtcaatg ataatctcgg cgttttcttc ctttaacatc tgccagcctt
    16441 ttaactgata cttagtgcct tttgtaagtc cgtctaattt gacagtatca acgattgtta
    16501 cctcttttcc tgcaaggatt gtcttttcgc cgtctttact ggttgctgtg gtatggatag
    16561 tgatttcctt ttcgtattca tcagtcaaag tccctaaatc aatcacaaga ttatttcttg
    16621 ataccacgat ttcaaatggt gggataagtt ccatgccttt gttgctgtca gagcgtaatt
    16681 cttcaataat gtaagtatcg taaggcaacg cacctttgct gtcgtctggt tcagaagttc
    16741 caaaccatac accgtcctcg cttgttttgc cagcgttggt attgtgcttg tgcgaagccc
    16801 attttgaaga agtggagaat tgcccattat cgtcagttac cacaacatga ctttcgcccg
    16861 ttgtcttgct tgtgatccta aagggaacat cagcaagacg cttgtgtgtg cctgcaccga
    16921 ttttcacgcc ctcaatatcc ccacgcttaa tctgattgta gatagagtgg gcttcgtctg
    16981 ttaagtccac gatttttccg ttttctgtga ttgtaaaatc aatcggcttc gcaccgtctg
    17041 tcaagtaacc gtttggagct tgtttctcaa cgatacggaa attcccgtaa ggcaaaaggt
    17101 cagcagaagt agaagcgata ccctcaatat ccgtatggat tgtttttaca acttcgtttt
    17161 tcttgtatat cttgccctca accaataccg cattatcatt taaggaaatg atgtcaaagg
    17221 cagtatcttt caaagtggca cttccttgtg gtttggtatc tttggtttct aaatctcgtt
    17281 tctgaatttt gacaccgcca cgaatgactt tatctgatac ggaaaactgg ttacttccag
    17341 ttaatacggc aaggtcgccg tcctcggtaa tctgcgtaag gtataaggct tttatctgtt
    17401 cttcactacc attcgcctgc atatatgcac cgtctagtaa gtagcccgtt ggcgatttcg
    17461 tttcttcgac cgttagtgta ccaagaggta aaaacgcttt tccgtcctgc atatagaagc
    17521 tatcgccaga taccttgtat gcgtctgcta attttgtgat gtaatgggtt gtcccgttac
    17581 tgtctgtttc agcggttgtc tttgtaaccc atgtacgagt agcttcggca ggaagattgt
    17641 ctttattgta gaagcctgca taatatttcc atgtaaactc cgccccctct aaagaagcgt
    17701 tcccttgtgg gttggctttc tgtgtttcca tgtcaatttt aaaaagctca atcaaagtat
    17761 cggtaacttt tggcgtatca gatactttca aagtcgctgt ctttccagct tcgactttta
    17821 aggaatacac cgtagtatca actttatacc ccaatggtgc agataattct ttgatatata
    17881 cggtagtagc tttgacttct gcaacctctg tatttccgct gtcgtcagtc gtaagggtag
    17941 caatctgttt ggtgcaatcc ttatcggaaa agacaccgta agtcgcacca gcgatagagt
    18001 aatttccgtt accgttagta atgctggtat tattggaagt cttttgaagt ttggcatttc
    18061 cgacatttaa cttcgcccag aattgcccta attcctgccc ctcgccagag tagatataac
    18121 cgccgcattc atagcgtcct ttgttttctt tcacaaaggc ttttgcacca gcaaacactt
    18181 catcttgtgt tgcctttggt atttcatcat aagaagctcg cacgttatca cattgccagc
    18241 ctaagtgaac actcaatctt tgccacacaa caagctgtct taaaaggtag gcgtgatttt
    18301 tgcttatccc attgtggttg tcggtgtatt gcttcacata ttcgatagat aaggcaacat
    18361 cacttatctg gtcggcactc atacgggagc ttgcgtcagc tctggtcttg tagccgttct
    18421 taaaatctgt gttaatatcg atacaataag cgtcctcgcc ctcaacggtc aaatgcccct
    18481 cgttaaaggt agaaccaatc gaaccgtcat tcattacttt ttcaacgata ccgacacgtt
    18541 cttcactttc cgtccagtat tgcttgcttt ctgcatggac aagtgtagtc ggtaaagcag
    18601 taacgacagt cgcaaaggca agtacgcccg tacacaatcg tttcaatatc tttttcataa
    18661 ttctaaatgc tcctttcatt ttgggtaata aaatagccgt ccataatgaa cggctggaaa
    18721 tagaaaagga acgtcaattt aggcgttcca tagtctatga aatattcaat ttttttcttg
    18781 cttcaatact gatgtgccgt accatatctt tgcatatcta ggaaaacttg cgtatcaagg
    18841 ctcattcatt ggtagtaaat tagtagtaaa ttgatgtgtt tgtttccttg aaaatgctga
    18901 tagatactat gttttagcgg ataatcaact ttttagtatg ttttttgcat aaaaattgag
    18961 tagatagtag ttttattgta cttaatgatt gtatttaagt gattagattt gaaattgaat
    19021 aatgtagata ataaaaaaat attaacagaa cttaataaac tccattaata tttttttatt
    19081 atttttgaaa ctgtgataat tatcacggaa gcatagaaaa taaagtgtta agatttaaac
    19141 aagatagtaa gtaagtaaaa ctaaaatata agaaaggtga taaaaatgaa actaaaatta
    19201 gattcatcta agttcaatga aggtctgaat tatctaaaaa aagactacaa gatatttgca
    19261 ccagttttaa taccatttaa aggtactttt tcagatactg atgttataag atacaaggag
    19321 gtaaacgctt ttgaagaaat ggaatttgct aagaaagcaa acttttcacc aaaagatgtt
    19381 gtacttccca taaatcaagt attgttttat tttactgaaa aagagtttaa ggaaagcgat
    19441 ttagacaaca agaaaatttt aattttctta agagcttgtg acataaatgg tataaaaaga
    19501 cttgatgaaa tatatctaaa taatggtgaa gaaaaagatt atttttataa aaatatcaga
    19561 gataaagtaa agtttgcact tgtagggtgt aaggaaagtt ttagaaactg tttttgtgtg
    19621 agcatggatt ctaacaaaac tgataattat tcaattggat taaatataga aggagataca
    19681 ctgtacttag atataaagga tagtgaattt gaagtattta atggagaagc aactgaattt
    19741 aatgttgatt atgtaactga taatttaata tctgtagatg tgccagagaa tattgattca
    19801 aatgaaatga taggaaattc aatatgggat gaatatgata caagatgtat aggatgtggt
    19861 agatgtaatt ttgtatgtcc aacatgttca tgttttacaa tgcaggatat tttctataag
    19921 gaaaacgaaa atgtaggtga gagaagaagg gtttgggctt cttgtcaagt agatggatat
    19981 acagatatag caggtggaaa ttcttttaga aaaaaacaag gcgaaagaat gagatttaaa
    20041 actatgcata aaatacatga ttttaaaaaa agattcggat atcatatgtg tgttggctgt
    20101 ggaagatgtg atgatgcctg tccgcaatac atatcatttt caaagtgtat agaaaaaata
    20161 aatgatttag taattagtaa ggaggaagta taaatgaacc catatatacc agtaagtgca
    20221 aaaatactag atatagttaa acatactgat aaagaatgga cttttagagt aaactgcaat
    20281 acaaaaggtg tattgcctgg aaagttttat gagatatcta tacctaaata cggtgaaagt
    20341 ccaatatcag tatcaggata tggagaggat tatattgact ttacaataag aaatgtagga
    20401 aaagtaacta gcgagttgtt taattataaa gaaggagatt ctttttttat aagaggtcct
    20461 tatggaaatg gatttgatgt atccctttat gaaggaagag aaattgtagt agtggcagga
    20521 ggaagtgcat tagcccctgt aagaggaata gttgaatatt tttataataa taaagaaaaa
    20581 tgcgaaaagt ttaaattaat agtaggattt aaatcaccaa aagatatttt atttgcagat
    20641 gatttaaaga gatggagtaa aaaacttgat attttagtta ctgtagatgg agcagaggaa
    20701 ggatatagtg gtaatgtagg attagtaaca aaatacatac cagaattgga tatgaaagat
    20761 ataaacaata cttctatagt tgtagttgga cctccaatga tgatgaaatt tacagtagaa
    20821 gaatttttaa aaagagattt agatgaaaag aacatttggg tttcttatga aagaaaaatg
    20881 tgttgtggaa taggtaaatg tggacattgt aaaatggatg atacttacat atgtttagat
    20941 ggaccagtat ttgattattc atatgctaaa aatcttattg attagggggt gaagtttgtg
    21001 ataagagatt taaataccaa aaaagtaatg aaaaatgctt atagaattac aaaaacaaaa
    21061 tatgagactt ctttaagagt tagagtacct ggaggtctta ttgaccctga gagtttagct
    21121 gtagtttcta aaattgcaag tgagtacggc aatggacagg tgcacataac tacaagacag
    21181 gggtttgaaa tattaggaat aaatatggaa gatatggaag aaataaataa aattatacaa
    21241 cctgttattg aaaaaatgaa tataaatcaa agtgagaaaa acgcgggtta tccagcagca
    21301 ggtacaagaa atatagcagc ttgtatagga aataaagtct gtccaaaggc tcaatataat
    21361 acaactgaat ttgctaaaag aatagaaaaa gctatatttc caaatgattt acattttaaa
    21421 gtggctttaa ctggttgtcc aaatgattgt ataaaagcta gaatgaatga ctttggaatt
    21481 attggtatgg ctttaccaat atatgaaaag gatagatgtg taaattgtgg agcatgtgta
    21541 aaaaaatgtt ctaagatatc tgttggagca ttaaaaacag aaaataataa ggtggtaaga
    21601 gataaagata agtgtatagg ctgtggagag tgtgtactaa attgcccaac aaatgcatgg
    21661 actagagatg agaaaaaata ctatagatta gctataatgg gtagaacagg aaagaaaaac
    21721 cctagactag cagaagattt tcttttatgg gtagatgagg acagcataat aaagataata
    21781 cttaatactt atagatatgt agaaaagtat atagataaag atgcaccagg aggaaaagaa
    21841 catataggat atataattga tagaacagga tttatggaat ttaaaaaatg ggcacttgaa
    21901 ggtgtagagc ttccagaaat aactaaaatg tacgaaaaca tatactggag tggaattaaa
    21961 tatctataaa ttgagtaaaa catatatttg aataaattaa aatttaatag aaggaagagg
    22021 gagttatgca taaagaaact ttggataaat taactaatgc agctataaat aagataaatt
    22081 tattaaacac aagtaaagta aaatatttgg tatcttctgc gtttgcagga ctttatgtag
    22141 gtataggtat acttttgata tttactattg gaggactttt gactgatgca ggttcaccta
    22201 tgactaagat agtaatgggg ttatcatttg caatagcact aagtttggtt ataatgacgg
    22261 gaacagagtt atttactgga aacaatatgg ttatgtctgc tggtatgtta aataaaggtg
    22321 taagtataaa agatacttct aaaatatggg catacagttg ggtaggtaat ttaatcggag
    22381 ctttggtttt aggcattata tttgtaggaa ctggtctagt agacaaagga cctgtagctg
    22441 aattttttgc aaatacagca gctagtaaag catccatgcc atttacagct cttttcttta
    22501 gagggatttt atgtaatatt ctagtatgtg tatcagtgtt gtgttcgttt agaactaata
    22561 gtgatactgc aaaaataatt atgatattct tatgtttatt tgcttttata acatcaggtt
    22621 ttgagcatag tgtagcaaat atgacaattt atagtgtttc attattttca ccaacaataa
    22681 gtacagttac tattggagga gctatttata atttagtagc tgtaacactt ggaaatattg
    22741 ttggaggagc tttatttatg ggtcttggaa cttatatatt aggtaaagaa aagcttaatt
    22801 aaatttattg tataaattat aactctcttg ataaatacat ttttagtatt gttgagagag
    22861 ttatttttat atttttgaaa aaatatttga aacaaaaaaa atatgggagc atacgaaaat
    22921 atatcggtta tatatataaa aaatacgttt atatatgaat tatatagttc taaatataaa
    22981 aaaagttaaa gtcctaccgt aaaaaagcgc attttgaata agataacaaa tatgataaaa
    23041 ttggtcttgt tgaaattttt aggggggata tgatgacaaa gaaactagta atatcaaaaa
    23101 caaagttgtt tatttttata atagcattta tttctatatt tatatattta tttggaagta
    23161 aaaatacact tataggtgta ggtatagtaa cagctatgct aacactcttg gaaagagatt
    23221 taactatttc tccaattaaa aatttactga agtatttagc aataaatata atcttaggaa
    23281 tactatcatt ttttgcagta caaaatatgt atttaggagt tttattaaat tttatagcat
    23341 tatttataat agggtatgta tttagttatg acttaaaaag agcagtatat gtaccctttg
    23401 gtctaatgta tatatttatg gtaagtatac ctgtaggaaa aagtgaattt cctatgagat
    23461 tgtcggcttt agctgttgga gcagttataa taatgattgc tcaatttgtt atgaatagaa
    23521 ataggatgaa aaatgtcgga gataaagaac tgatatctat atgtgatgaa ttattagaaa
    23581 aaattagcct tttaaaaaat actattaatg atgatagttc tataattaaa tctagtatga
    23641 gaaaaataga tagctgtaat tatagaataa attctatatc taaaaatttg aaaatggtta
    23701 tttttgataa tagaaaagat gacttttata tcagtattag aggtatagac ataatgaata
    23761 ttttattttc attagaaaga ataagtttaa tcctggaaag atacaaaaag gatagtaaag
    23821 aatttgaaga tgaagatata aaaaatattt tagaagaaag tagcataaat agtaaatcag
    23881 atgttttagt tgtagcaacg aaagaaataa actatattaa gatgtgttta gaaaataaag
    23941 ataccataac tgataaagag atattaggat ttagagatta tgttattgct caggatacta
    24001 aaaatataaa tttaaaagaa atttatagtg ttttagaaaa tttatatgag tttttagtag
    24061 attataaaaa agtaaaatca agagacgaaa agaaagctga aagaaaatca aagatacctc
    24121 atgaatttaa acgactatca atatataaga aaaactttaa tttaaattct ataagatttt
    24181 cttatgcagt aaagattgct ttagctacag ctgtagcggg ttttattatg gattatttcc
    24241 atttaagaga tggaagatgg ataatgttaa ctgtcttttc attaacacaa ccttacgcag
    24301 aaaattgtat acaaaggtct agaaaaagaa tagaaggtac atttatagga gctgtaatat
    24361 ttattgtatt attttcaata ataaaagata gtacattaag gtcgttaata gttcttttag
    24421 cagggtatat aaactcttat gtagttgatt atagaaaatt aatggtatgt gtaactgttt
    24481 cagctcttgg ttcagcagta gttatgggag acccaaatgt tttaacaata agcaggattt
    24541 catatgtagc attaggagca attattgcat taatagtaaa taagtttata ttaccatatg
    24601 atgctaaaac aggctatcaa catgttatag aaatgtataa aggaatagtt aaaaatataa
    24661 ttgatgaagt caataagtct atagaaaatg tagctgatgt ttactatata aaaaatttat
    24721 tattgatacc atcacttatt gaagatagac ttatgttgat aaatgctata tataaagata
    24781 aacatcaaga ggatttttta gaaaatcaga aattactaat aagtaatatg tataatctat
    24841 atataaatgt taataaaaat aaaataaaag atgaagatgt tgaaaaaata ttgagagata
    24901 ccaattatat ttcaaattac aatgtagata agtatgatga aggaagaagt gtaattttag
    24961 agagtattgt aaatactaaa agtctaggtg acaagataat atgtctaaac ttactgcaaa
    25021 ctctaaatgg tgtcaaagaa atgtatagaa taagtaatat aactaaagtt tcaataaaag
    25081 aagcagctta gatattaaat tatagaatag ccatatattt aaaataaagt atatggctat
    25141 ttgttttata aaatactaaa agaaaataat atataaaaaa caaaaaacat atatttatga
    25201 attttatatg aaaatagtta aaatattgat ttttttcatt ggttgaaaaa acaatttact
    25261 taggataaac tataatagta ttcaaatatt atgggggtta gatttatgag taaagatgta
    25321 aaggtaaagc gtaataagaa atatgataca tttagtataa ctatggaact tgagagacct
    25381 ttactttatg atgaggttga gaacaaagat gataaaaata ataatagaaa atttaacata
    25441 aagaataaga tatttaaggg aataggtata ctatttgtat tgattttgct tggctttttc
    25501 atatggataa ataaaacata tgaacctcaa aagctggcaa aagaagctct agtcagcaat
    25561 agtaaagttg aagtaactgt aaatgaaaac atttcattta caccaaaagg aagaaaagtt
    25621 tctaaaggtt taattttgta tccaggagct aaagtagaaa tagaatctta tgctccactt
    25681 gcaagaaaaa tagcagaaag tggatatgag gttgtaatcg taaagatgcc acttaatcta
    25741 gctatacttg gaactaataa ggcacagaaa gttatggatt cttacaacaa catagaacat
    25801 tgggtaatag gaggtcattc attaggagga gttgcagcat caaattttgc acgtgataat
    25861 aaattaattg aaggcgttgt atttttagct tcttatccaa tgggtgatga gttgaaagaa
    25921 ttaggaaaaa aagttatatc tatatggggg agcaaagatg gagtagtcaa ttttaaaagt
    25981 cttgtagaat caaaacaaaa acttcctgat gatacaactt atgttgagat tgaaggagga
    26041 aatcatgcac aatttggaga ttatggaaaa caaaagggag ataatgatgc tattataagt
    26101 caagaaaaac aacttaatat tactgccaat agtatcatta aatttttaaa gaatatatct
    26161 taaactaaaa tttaaaaaat ataattttat aagttattat ttaaagtaaa tattaataat
    26221 ataatagaat gaatatttta ttacaagggg gattttaata tggaatacga tatgccactt
    26281 tacagaccac caagtgaggc ttatagtctt ataatacaag tcacactagg atgttctcat
    26341 aacaaatgta cgttttgtag tatgtacaaa tctaaaaaat ttaaaataaa gccactagaa
    26401 gtaataaaaa atgaaattga tatatttaga agatattata agcatgtaga aagaatattc
    26461 ttagcagatg gagatgcatt gataatacca atggagaaat taagagatat tatcttatat
    26521 ataaaagaag tttttccaga gtgtgaaaga attactatgt acggctctcc taaatctata
    26581 gagaaaaaat ctgatgatga acttaaagaa ttaagaaaac ttggtgttaa aatgatttat
    26641 ctagggcttg aaagtggaag caatgaagta ttagaagata ttaagaaagg ttttagtagt
    26701 gaacaattaa taaaagttgg tagaaaagtt aaaaaaagtg ggattaaatt atcagccact
    26761 gtaatagcag gtcttggagg aactaaaaaa acacatcagc atgcagttga tacaggaaaa
    26821 atgttaggag caatttcacc agattatgtg ggtgtactta gtttaatggt agaacctaat
    26881 actgaacttt acgatttact taaggcagga gagtttacaa tactagagga taaggctgtg
    26941 ttacaagaaa ttaaagagat gataaagaat atagatgcta atgaaaaaat tgtatttaga
    27001 agtaatcatg catcaaatta tgctaattta aaaggtgtat tacctgatga taaacaacgt
    27061 ctaattgatg aaattgatta ctatctaagt aaccaaaagc taaaaagaga agaatataga
    27121 agactatagt ttttgatata tcaatctata ttgataggta aatactaaga ttatttagat
    27181 acaaaaaatc atgctacatt aatagttgct tactattgat gtagcatgat ttttttatta
    27241 aaaaacaaaa tggtatattc atatataata tatcaataat aatgaaaatg tgaactagtt
    27301 taatagaatt ttacctatta taataaaaac aggaatttaa ataataaaaa gtaaagtaac
    27361 ttttta
//
LOCUS       DAMJVG010000050        27357 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.050, whole genome shotgun sequence.
ACCESSION   DAMJVG010000050 DAMJVG010000000
VERSION     DAMJVG010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27357)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27357)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27357
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.050"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(<1..598)
                     /locus_tag="PC512_002353"
     CDS             complement(<1..598)
                     /locus_tag="PC512_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HDF2442092.1"
                     /translation="MLNETRKKQLTEVCQDLIRNASYSGQEENVVKAIEENFALLGFD
                     SWSRDRYGNIVGCIKGNKPGKKILFDGHIDTVPVPDASKWSVPPFEARIVDGKIYGRG
                     TSDMKGQVSAMMAAVSYFAEDTNKDFEGELYVAGVVHEEIFEGVSAREISKAVQPDYV
                     VIGESSELNLKIGQRGRGEIVVETFGKPAHSANPEKGIN"
     gene            complement(931..2145)
                     /gene="dpaL"
                     /locus_tag="PC512_002354"
     CDS             complement(931..2145)
                     /gene="dpaL"
                     /locus_tag="PC512_002354"
                     /EC_number="4.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HDF2442093.1"
                     /translation="MREIKWKLNNLPKSEEKEKGIEFLKDEEIAKAKAFHESFPQYEK
                     TPLVKLDNLAKSLGVSGIYVKDESYRFGLNAFKVLGGSYSMGRYLAQRLNTDISELGY
                     DKLTSKEIKEKLGEITFFTATDGNHGRGVAWTANKLGQKSVVLMPKGSSEFRLNKIKG
                     EGADASITDLNYDDAVRLANDYAEADDHGVMVQDTAWDGYEEIPAWIMQGYGTMAKEA
                     IEQLKEYGVDRPTHVFVQAGVGSLAGAVQGYVASIYDECPITVVVEADEADCYYKSAE
                     AGDGKPRFVGGDMPTIMAGLACGEPNTIGFEVLKNYSSAFVSAPDWVSAKGMRILGNP
                     LRGDEKVISGESGAVTTGALVSILESEDLKDLREALKLDENSKVLLISTEGDTDPDKY
                     RDIVWNGECQSK"
     gene            complement(2759..3296)
                     /locus_tag="PC512_002355"
                     /pseudo
     CDS             complement(2759..3296)
                     /locus_tag="PC512_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427977.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="2'-5' RNA ligase family protein"
     gene            complement(3373..5178)
                     /locus_tag="PC512_002356"
     CDS             complement(3373..5178)
                     /locus_tag="PC512_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2442094.1"
                     /translation="MLSKLKEFQQEMIKYTETVASVLDVDIEIVDDRLIRISGTGLYK
                     SKINESVVTEGFIYDNVIQTGQELVVLDICDNQLCIECSHYMKCLNKVIIAVPIKYNN
                     RTIGVIGAISTDKTKKVEISAKIDNYLKFVNHICDLISMKIEEHEASKNSSRKMDMMI
                     EIIENVEKGVIILDINSKISYINNIALKKLDIDKNIIENIVNIVSVESSSNGHELLEI
                     DIDNKIYNINAKIIPVYPYINQYDKIIIFDKTYINHKGHGKVNSGWGNSDIESIIGNS
                     EAMLKVKERTKKLAKSNSTVLITGESGTGKELIARAIHAEGSRWNKPFIAINCAAIPE
                     NLLESELFGYIKGAFSGASSGGKVGKFELANEGVIFLDEIGDLSMPLQAKLLRVLQER
                     KFARIGSNKLIDLDIRVIAATNKNLLKLVNEGKFRDDLYYRLNVIPINLPPLRERKDD
                     IEAIMMKFASKYSLELGIQLNKIEENVMNMLINYNWPGNIRELENAVEYMMNLVGDDG
                     IIYKDMLPLDILNYYNINGNIYKNKDVNIIFEDDIVGGIVENQERILSIKELELTYIN
                     KLLNKYGRDTKTKKKIAKDLGIGLATLYRKLEEEQ"
     gene            complement(5574..5951)
                     /locus_tag="PC512_002357"
     CDS             complement(5574..5951)
                     /locus_tag="PC512_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003483933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HDF2442095.1"
                     /translation="MSKVVIATEKAPGAIGPYSQAIQVGNIVSTSGQLPIDMKTGELV
                     SDPKEATKASLDNVKAILEQAGTSMDKIFKTTVFVKDLKDFNDINEVYATYFKENPPA
                     RSCVQVAQLPKDAVLEIEAMAVL"
     gene            6856..7341
                     /locus_tag="PC512_002358"
     CDS             6856..7341
                     /locus_tag="PC512_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442096.1"
                     /translation="MSKSELTAETTEEMLEVLSGKDYDIACHLHELGKSLDCKIEPKT
                     GARSYKIVYSTKKPKRSLFTIECNEKKWRVKANLFHLNTYKDAVEECSKTIKDSITKT
                     RTCKKCNSKCIGGSSFELDGKSYLTCIGSGHYFANMEEMDWKNLEKLITKENNIMQES
                     V"
     gene            complement(7541..8080)
                     /locus_tag="PC512_002359"
     CDS             complement(7541..8080)
                     /locus_tag="PC512_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF2442097.1"
                     /translation="MSKNVLIVSASPRKGGNSDLLCDQFIQGVLESKNQVEKIFLKDK
                     DINYCTGCGACYEKEANCSQTDDMGEILEKMIGADVIVLATPVYFYTMNAQMKTMIDR
                     TCSRYTEICDKDFYFIVTAADENVADMERTIEGFRGFTSCLNGSKEKGIVYGVGAWNV
                     GDIKGSKAMKQAYEMGKLA"
     gene            complement(8073..8486)
                     /locus_tag="PC512_002360"
     CDS             complement(8073..8486)
                     /locus_tag="PC512_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2442098.1"
                     /translation="MTISEVSKKYELSADTLRYYERIGLIPPVNRNKSGIRSFTEEDC
                     EWVNFIKCMRGAGLSIETLIEYVAMFQQGSSTIKARKELLIEQRNQLAKRIEEMQKTL
                     ERLNFKIDRYEEGIIEKEKVLKSSRNKKMEAVSYE"
     gene            complement(8522..9643)
                     /locus_tag="PC512_002361"
     CDS             complement(8522..9643)
                     /locus_tag="PC512_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HDF2442099.1"
                     /translation="MEAKKLGFGLMRLPIKDENDVTTIDMEHLNKMVDTFLERGFTYF
                     DTAYVYHMGKSEIALRESLVKRHKRESFTIATKLPLMALKKKEEQETIFNEQLEKCGV
                     DYFDYYLLHNIGVSHYEVAKKFDSFKFIEEKKKEGKIKNIGFSFHDSAELLDKVLSEH
                     PEVDFVQLQINYLDWDNESIQSRKCYEVAEKHNKPVIVMEPVKGGTLAKIPEKAEKLL
                     NDYNPDMSISSWAIRFAASKDNVMMVLSGMSNMEQLLDNTGYMQNFKPFVQEEYNIID
                     EAVEIINESILIPCTACQYCVEGCPKNIAIPNYFALYNAEKQALNTGFSTQMVYYNNY
                     TKTYGKASDCIECKQCEESCPQHIKIIDALKNVAETFEK"
     gene            10242..11894
                     /locus_tag="PC512_002362"
     CDS             10242..11894
                     /locus_tag="PC512_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp21"
                     /protein_id="HDF2442100.1"
                     /translation="MNKKNLAILISGMMFFSSSSAIFADNTTKQERLIGKTRYETAVE
                     VSKLGWVQSKTAIIVNGNSIQSALCANPFAKLKNAPILLVNNNSIENSTKAELKRLGV
                     DNVYIVDSGNSISSKVENEIKSLNIKINKIVGNNIYEMSTNVLKEIDKIKKIENVAVV
                     NGLKGLSDAVSIASPAAIHNMPIILVSDENSNDSSINFLNNRSIKKSYIVGGNKILSD
                     NTVKKYPNRERISGSDRNNTNAKIIDKFYKDKKINNVFVAKDGINQENALVDSLSIGV
                     LAAKENSPIMISNGSLVNSQKEFIKNKDIDEITQVGGGYNQKAFEDILKLKNVNIRNK
                     TKKISLIQAKEILKQALPGSNILVCYYDEDDNEYDCKVIKDNILYEIEIDAYSGKIIE
                     IEKDDDLNDNNLGTQNISLDKAKSIALDAIPNGNLIYCKYDAEDNEYEAKVIKNKKTY
                     ELEISAFDGRIVDIDMDNDSDDDFDDNDKNNSNTNDNSSIISAEKAKSIMLDKVPGGK
                     IVKFKYDEDDKEYEGEIIKGKTEYEITINAITGKILEFEIDD"
     gene            complement(12277..13203)
                     /locus_tag="PC512_002363"
     CDS             complement(12277..13203)
                     /locus_tag="PC512_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conserved phage C-terminal domain-containing
                     protein"
                     /protein_id="HDF2442101.1"
                     /translation="MSNSFYQLNSAVLYFNEKRDVNRIRFNHYVMRKENIQRLKGTLP
                     RGQFMMTVRKAASDLDVSISTISRLVNEFIDLGILRLISRGVKGNCCSVYSYVCSESS
                     NAEIVTKNGDIFKNIEKYIDATINNNQKTMKYKHRNELFKNSNTNIYSRINQESIDKD
                     YDLIIHTGYETENETKKKELLKNNLNKKNLNKNTFENSDEDLTEDSTYKNPESIHEII
                     IRKLNSESGKNFKADLSITKALIDKRLKEGYSLEDFYKVIEAKVRRWRYTDMEIYIEP
                     TILFGYEFESYLNEESSLSACNYGDMCYEDMY"
     gene            13793..14713
                     /locus_tag="PC512_002364"
     CDS             13793..14713
                     /locus_tag="PC512_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF2442102.1"
                     /translation="MTNAKSKKEYLNRICKVQDYIEEHLHEPLSLDELSNIAGFSKFH
                     FHRIFKAIEKETLAQYVNRLKLENATAFLIHRTDMTVTDIAHYFGFTDSAVFSRAFKN
                     YYKISPIKYRNNYSKNCKEPYKISQYNRSISKPKCKNTREVKGEIEILELDNMNTIYT
                     RYTGSYGNLTSTFPKLLERLFTYASEQNLLGLENTQILAIYHDNPQFTQEHQLRTSIC
                     MTIPDNIVVKENDNLGNMIIPSGKYLVGHFDISKSEYSDAWDFMYNEWLSNGNYKLRA
                     SFPFEVYLNNPHNHPQNRHLVDIYLPIEPF"
     gene            14799..17219
                     /locus_tag="PC512_002365"
     CDS             14799..17219
                     /locus_tag="PC512_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HDF2442103.1"
                     /translation="MKEIKINGAKIHNLKNIDVSIPKDKLVVATGVSGSGKSSLMFDI
                     VFEEGRKQYLQSLGILAGIDSEDKFDNIQGLAPTIAVQQNIIRQSNPRSTVGTRTNIL
                     NMLTLLYSVEGQIMCTMCDTPVSDNLICNNCGYEEERLRPSYFSYNSSDGMCMKCSGH
                     GAYFEINIEKLVLDKHDTLKQVLDRAKITPGYLRVFSKKFNDYLDIQFLQLPEEIRNE
                     VLYGHYENGKKSSSLSKVFHNRYKRGEDLNGVYTMTACSDCNGFKIGEEARRVLLNGK
                     HIGELGKMTILEIDDFLKLLINQGNLNTFGTNLVNDILSKTQHLIESRLGHLSLYREM
                     STLSGGEMQRLFLNSHLDSEMDSLIYVLDEPTAGLHESEKIDILKSLKKLKDLGNTVI
                     VVEHDKNTIEMAEHIIDIGPKAGVEGGQLVYQGDLEGLLQSDKSLTGQYLSGKYPMPN
                     RTSNKNITHTDKIPCITIQNANTNNLKNVTVSLPLGAMVGISGKSGSGKSSLISDTLL
                     PLLRSQFNNHTINNQINSSESEIGEEDDYAVVETIADRLIGTKHISGYSEISQSPIGK
                     NMNSTPASYIGIWDKIRTLFAGQPESLEQGFTAGHFSFNSKGACPKCSGSGYEKVWLG
                     NNLSIDHICSECQGKRFNDESLSIKYKNKNIHDILNMSVSESVHFFKDIPNIVSHLNV
                     LEQIGMGYIKLGQPTPTLSGGESQRIKLAKEIGKKRNGNILYVLDEPTTGLSLYDTSK
                     LIQLLDELVENGNSVIVVEHDIDVLNVCDWIVELGPEGGDKGGYIIAEGSPKTLKENP
                     KSITGRYL"
     gene            17219..18241
                     /locus_tag="PC512_002366"
     CDS             17219..18241
                     /locus_tag="PC512_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HDF2442104.1"
                     /translation="MNKNNCLDLIFEKVDPSSVGMSSEKLSQLEPLIISQYSNINGII
                     IARKGKIVFEKYYNGYNADDTFHVASVTKSIISALIGIAIDKGYIKDVDQKVVDFFPE
                     YTCSPSEICKKAVTIRHLLTMTAPYPFKNMTESLERLCKQKDWIKYTLNQLGQKGEIG
                     TFKYSSAGTHLLSAIITKTTGKSAREFANEYLFKPIGMKVIPDYDMKDFGFEDFFGKN
                     LKGWAKDRQGYSIGGWGLTLSARDMLRFGFLYLNDGIWNNKRIISKSWIEESVKMNSN
                     EYGYLWWLCKKDGVLWYSAMGTGGNAICCIPQYDLVIAIPSKIVFKPRDRWEFIEKYI
                     LTSIID"
     gene            18394..19140
                     /locus_tag="PC512_002367"
     CDS             18394..19140
                     /locus_tag="PC512_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2442105.1"
                     /translation="MDTYTTSEVADLIGVHPNTVRLYEELNLIPKPKRNTNGYRIFND
                     FHIEQFRFARTALKIEVVQRGLRKDALEIVRTSANRDFDKAISLVNQYLQQLEIEKSN
                     AEEALTIVAQILNGNTPETNKLFLTRKETAEHLNVTIDTLRNWEMNGLLKVKRKQNGY
                     RVYTDEDIKRLKIISALRCANYSLSAILRMLNALSSSPNTNIKTVLDTPKDDDEIISV
                     CDKLITSLKEAEHNAKTMKSHLQIMKKQFS"
     gene            19226..20476
                     /gene="cme"
                     /locus_tag="PC512_002368"
     CDS             19226..20476
                     /gene="cme"
                     /locus_tag="PC512_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter Cme"
                     /protein_id="HDF2442106.1"
                     /translation="MENKNTNSTWKKKVILFLASQYISLFGSSLVQMAMIWYVTLQTS
                     SGVWVTVLTVCSFIPQMIISFFAGVWADYYNRKVLIIVSDSTIAISTLVLILFMMSSN
                     GTTSELIAISVISVIRSLGSGVQTPAVNAMIPQLVPEEHLMRFNGINSSLQSIVQFIV
                     PIVAAAILGFGNKINQVLLIDVFTAIIAIVLLIFIKIPKHDIPKQTEKVSFFADMVSG
                     IKYCFSDKFIRKVLFTYGAFMLLCVPSGFLIGLLIERTFGKGYIYLSIIEMIGFLGMV
                     LGGLIIGVFGGFKNRNKTFFLAILSYAIFSIILGLVTQAWQFFIFMFFTNFSIPIIQA
                     SAMTMLQEHVAPQMLGRVLSLPIIIYTGFIPLGMMIFGPMADVISINNLIIIAGIILL
                     FFALAIPYSKQFYKQGISKSNESE"
     gene            complement(20993..22006)
                     /locus_tag="PC512_002369"
     CDS             complement(20993..22006)
                     /locus_tag="PC512_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2442107.1"
                     /translation="MIGLRYQLKSIKKDKMCIISFFLPVVMAILINFMGTIDISSLGE
                     IRFGIVKDTLPVQTEQWLKKYGMVSVYDTKMHLIREIKDIKTDTIGVVRDGKGIKTVF
                     YGNEINAIKNVGKTLPEMFRLKGDLKDVEVTILPKDSILKEFQNVFIAMILITAMFMG
                     CTFNAMNIISEKEDGISFINEVLPQSRSQYIIQKVFLGLLCGCLSSMITVFICLDISI
                     LDMIMMLLLVVFSAFISSLIGLFIGKLSEGLMVGIVYIKIVMILFIGTPLLIYLLGVN
                     TSGIGNLCYIMPSVATFNGIMEIINGNVIIIKDIVILAVHCVVWFMIYIILDKKRKLS
                     FSR"
     gene            complement(22009..23037)
                     /locus_tag="PC512_002370"
     CDS             complement(22009..23037)
                     /locus_tag="PC512_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2442108.1"
                     /translation="MYSKFFTLVKKDFWMMIYGKFFVLTLGSLILYSCYINFGYVKFM
                     DEDSYHNNVYLYNPENISMSASPLINQVSSIGELKAKLDEDTSAVCIDMSSSKPKVIL
                     HESIKGVDNYRADYALSLLSSEKDHNSKISDNNAIIQINDKDTSEIKQRKDMTCEILF
                     FEIVAIGFLGIASLLFKEKQMGVMRITGILPVKRSLFILSKIFAFFICDLCFTVLLVV
                     FNIGFLEGIKILPQVLVQASILSIIMSLIGIGCSMLLRDFKQFSLIYLVVAVFITTPI
                     FLSANTSFEIDWIKYHPFYHVYSQLKNAFFMNFSKELVYFVVCSLTIIVLFLLVKYIF
                     NKELVREG"
     gene            complement(23037..23882)
                     /locus_tag="PC512_002371"
     CDS             complement(23037..23882)
                     /locus_tag="PC512_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2442109.1"
                     /translation="MIKVRELKFSYGKDKQILHGLNFEVKEGEIFGFLGPNGSGKSTT
                     QKILNGVLKGYNGHVSIFGKEVKAYTESLYQKIGVLFEFPYLYTNLSAIDNLEYFSSF
                     YPKNQRRDIYELLDLLEFKKEFINKPVSSYSKGMKQRISMARALVSNPKLLFLDEPTS
                     GLDPSGAVLFRKIIEEERKKGTTIFLTTHNMLDADLMCNNVAFIADGKIMVIDKPKNL
                     KMKNSNNKVEVEFVYNGNRDIEIVDIQELESGITFKYDEILSVHSKEPTLEEVFIKYT
                     GRMLV"
     gene            complement(24313..25443)
                     /locus_tag="PC512_002372"
     CDS             complement(24313..25443)
                     /locus_tag="PC512_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2442110.1"
                     /translation="MNSLRKIIEKLKNVDISNWIKQNFGLYSVRKKVFLLSKLSGALI
                     ILFYLVVEEFSINSKFEFWIWFIILVIFIMSIDFLLGKFISEPITSINKSAKSMSQLD
                     FSNPCTVNTNDEFGELSRSLNTMSTNLQQALSDLESANIQLEKDVNKERMLLEQRKEL
                     VDTISHEMKTPLGIIRAYTEGLIDEVDEEKKKNYMNVIIEETDRMNNMIVSLLDLSAL
                     EAGVSKLNPERFDFIEFVETVAGRLLIDIPDANFYFTYDLPEYEVFVVADKMRMEQVV
                     ENLVINAKKHVVYNGNLDLSITCENGLLLFEIYNDGRFIEQDEISKIWSKFYRSVQSQ
                     RTGGSGLGLAIVSQILTMQGLEYGVNNRDRGVEFYFMIPIDE"
     gene            complement(25440..26111)
                     /locus_tag="PC512_002373"
     CDS             complement(25440..26111)
                     /locus_tag="PC512_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2442111.1"
                     /translation="MAKILVVEDEKRMQNIIVEYMQKGGYTCITADDGVEALTILKSN
                     NIDLMILDIMMPYLDGFSVCRVSREMTNIPIIILTAKGEEEDKLKGYEYGADDYITKP
                     FSPKVLLAKVNALLRRYTTDIPKNSLSLGKIFIMVASRQVYVEDKLIDLTYKEFELLR
                     LFMENPNQVFSREKLLNCIWGYDFEGNTRTVDTHIKTLRKKLGSEGHHIVTLIRSGYK
                     FEVKE"
     gene            complement(26314..26964)
                     /locus_tag="PC512_002374"
     CDS             complement(26314..26964)
                     /locus_tag="PC512_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HDF2442112.1"
                     /translation="MDFISSILQGLLSILFNFTGDFGISIVLITLIVKLVLMPLSLKQ
                     RFSVKKQQELAEKMEYIKEKYKNDTKELEKQIQVSSVESMKSMLGCLIVLVQMPVVYA
                     LYHVCLDMTKEFTTIIIPWIANLGTFDNLFILPCIYTLIMLASNLVNYIPYLKINSQV
                     KFNKQMAVVTTITSLILTVRTPVAIGLYFITSAIYSLIEDICFRIYFNRKNRIVTK"
BASE COUNT         9491 a         4424 c         3298 g        10144 t
ORIGIN      
        1 catttatacc tttttctgga ttagcagagt gagctggttt accaaaagtt tctactacta
       61 tttctcctct acctctttga cctatcttta agtttaattc tgaagattca cctattacaa
      121 cataatcagg ttgaacagcc ttacttatct ctctagctga aacaccttca aatatttctt
      181 catgaacaac acctgctaca tacaattcac cttcaaagtc tttgttagta tcttctgcaa
      241 agtatgaaac agcagccatc atagcactta cttgcccctt catatcagaa gttcctctac
      301 catatatttt cccatctact attctcgctt caaaaggagg aacactccat ttacttgcat
      361 ctggaactgg aactgtatct atatgcccgt caaataatat ttttttacct ggtttatttc
      421 cttttataca tcctactata tttccatatc tatctcttga ccaactatca aaacctagta
      481 aagcaaaatt ttcttctata gcttttacta cgttttcttc ttgacctgaa taactagcat
      541 ttcttattaa gtcttggcat acttcagtta attgtttttt tcttgtttca tttaacattt
      601 tgatattccc ccatataatt tttagtttgt tgacgtttta ttttgatatt tcactttttt
      661 aatttattag catttcactt aatctattga ttttttattt ctttatattt tatttattaa
      721 atttttattt agactttatt ttaattttat ttggttttat ttaattttat ttagttttta
      781 ttttgaattt ttcatttgct ttactttttc atttatttag atttttcatt tgttttagtt
      841 tttattttat ttaaagtttt cacttattta agtttttatt ttccttaaat ttttcattta
      901 tttgttaagt ttttattttc cttaagtctt ttatttactt tggcattcac cattccaaac
      961 tatatctcta tatttatcag ggtcagtatc tccttctgta cttattaata atactttaga
     1021 gttctcatct agtttcaaag cttctcttaa gtcttttaaa tcttcacttt caaggattga
     1081 aactaatgct ccagttgtaa ctgctccaga ttctccagag attactttct catctcctct
     1141 tagagggttt cctaatattc tcataccttt agcagatacc cagtctggtg ctgaaacgaa
     1201 tgctgatgaa taatttttta acacttcaaa acctatagtg tttggttctc cacaagcaag
     1261 ccctgccatt atagttggca tatctcctcc aacaaatctt ggttttccat ctccagcttc
     1321 tgctgattta tagtaacaat cagcctcatc agcctctact actactgtta ttgggcattc
     1381 atcatatatt gaagcaacat acccttgaac tgcaccagca agtgaaccaa ctcctgcttg
     1441 aacaaatacg tgtgttggtc tatctactcc atattctttt aattgttcta tagcttcttt
     1501 agccatagtt ccatatcctt gcattatcca tgctggtatt tcttcatatc cgtcccatgc
     1561 tgtatcttga accattactc catggtcatc agcttctgca taatcattag ctaatcttac
     1621 tgcatcatca tagtttaagt ctgttatact agcatctgca ccttctcctt tgattttatt
     1681 taatctaaat tcagaagaac cttttggcat taatacaaca gatttttgac ctaatttatt
     1741 agctgtccaa gcaactcctc taccgtgatt tccatctgta gctgtaaaga aagttatttc
     1801 tcctaatttt tcttttattt ctttcgaagt caatttgtca taccctaact cagatatatc
     1861 tgtatttaat ctttgagcta agtatctacc catagagtaa gaaccaccta aaactttaaa
     1921 tgcgtttaag ccaaatctat aagattcgtc tttaacatat attccgctta cgcctagtga
     1981 ttttgctaag ttatctaatt taactaaagg agtcttttca tattgtggaa agctttcatg
     2041 aaaagcttta gcctttgcaa tctcttcatc ttttaaaaat tcaattcctt tttctttttc
     2101 ctctgattta ggtaagttat ttaatttcca ttttatttct ctcatttatt ttatattccc
     2161 ctttcaaatt tttcggtgtc attttaattt tttatctttg tgccttatag caaagcaatt
     2221 accgtgccaa tattatttat tctaaaaaca atttttttat gttggaatta catactttta
     2281 taaaatttct ttaaagttta taaattttga gtgtgaaaaa taagatttat aaaagaaaaa
     2341 attctcatat tgggaaattt ttatcaatac gagaattatc aattcgagaa atcgtttatt
     2401 tatcttaatt cttcctttat tatgctctta ttttttatat gtctattgtt ttgtcagata
     2461 tattactact tttattttct ataaatatat ggctataacc ttcttacgca taaactctat
     2521 aaatttatat actttattac ccaaatattc tttattaccc aaagcctcca aaatggctta
     2581 aatcttttca tagcttctta cagaagttta catggtcgtc cccccaataa gcaaaagtgc
     2641 aatatgtgta ccattgtgcc ctacttgcga ctattgagct gtcgaaattc gcaacttcgc
     2701 atttatctga tgaaatgcac tatacaaaat attcataaca tccacaacag agttaaagtt
     2761 acctattcat attcactgta aaaatttctt ccacaggaaa tgtaatttta accaatccta
     2821 ttgagacaaa ctcaccactt atttttttga actcacgcag taatacatca cttgcccgaa
     2881 aaaaagcctc actttcatca tctccagtaa gtgctattgt gcaatggggt acccaacgat
     2941 tggggtggta ccattcccaa ccatttgaat caaaatcttg tagtacctca tataattctc
     3001 tctgaaactg atacattgct attcattata ggtgatacaa acaccgtttt agtatcatta
     3061 aacatgccta ctgaaccaat gtaagcaggt attaccttat ggttttgtgc aaaccccttt
     3121 agcttgtcta tgcaacaagc ctcatccaca tcattgaaac aagccaaagt aagatgaggt
     3181 cttgttttcc attctaagta cttcgtacta attttttcat cagcgatttt tttagataaa
     3241 tcaaaaagtt gcttttccgt ttttttatca taatatagct ctatcgcata ttgcataata
     3301 acacctccac cataaagtaa aaatacctat ctataaaaac acacaaatac ctatcatttt
     3361 aatattatat tactactgtt cctcttccaa ttttctatat agtgtagcca aacctatgcc
     3421 taagtctttt gctatcttct tcttcgtctt tgtatctctt ccatacttat tcaacaactt
     3481 gtttatgtaa gtcaactcta attctttaat tgaaagtatc ctttcttgat tctctactat
     3541 ccctccaact atatcatctt caaatattat atttacatcc ttatttttat aaatatttcc
     3601 attaatatta taatagttta aaatatctaa tggaagcata tctttatata ttattccatc
     3661 atctccaacc aaattcatca tatattcaac tgcattttcc agttccctta tatttcccgg
     3721 ccaattatag ttaatcaaca tattcattac attttcttct attttattta actgaatacc
     3781 taattctaaa gaatatttag aagcaaactt catcattatt gcctcaatat catcctttct
     3841 ttccctaaga ggtggcaaat ttataggaat tacattcaat ctatagtata aatcatccct
     3901 aaacttacct tcatttacta atttcaataa gtttttattt gtagcagcaa tcactcttat
     3961 atctaaatct ataagtttat ttgacccaat tctcgcaaat tttctctctt gtaaaactct
     4021 aagtaacttt gcttgtaaag gcattgacaa atctcctatt tcatcaagaa atataacacc
     4081 ttcatttgca agttcaaatt tacctacttt ccctccacta ctagctccac taaatgcacc
     4141 ttttatatag ccaaatagct cactttcaag gagattttct ggaatagcag cacagtttat
     4201 cgcaataaat ggcttgttcc atctgctacc ttcagcatgt atagccctag caattagctc
     4261 tttacccgta ccactttccc cagttataag tacagttgaa tttgactttg ctaatttctt
     4321 agttctctct tttactttta acattgcttc tgaatttcca attatagact ctatatcact
     4381 atttccccag ccactattca cttttccatg tcctttatga ttgatatatg tcttgtcaaa
     4441 tattattatt ttgtcgtatt gatttatata tggatatacc ggaattattt tggcatttat
     4501 attataaatt ttgttatcaa tatcaatttc tagtaattca tgtccatttg aggaagattc
     4561 aacagatact atatttacta tattttctat tatattttta tctatatcta atttttttag
     4621 agctatattg tttatataag atattttgct atttatgtct agtattataa cgcctttttc
     4681 aacattttca atgatttcta tcatcatatc catttttcta ctgctatttt ttgacgcttc
     4741 atgttcttct attttcatag aaattaaatc gcatatatga ttgacaaatt ttaaataatt
     4801 atctattttt gcacttattt ctactttttt agttttatct gtgctaatag caccaattac
     4861 tcctatagtt cgattattat actttattgg aactgctatt attactttat ttaggcattt
     4921 catgtaatgg gaacattcta tacaaagctg attatcacat atatccaata cgactaattc
     4981 ctgacctgtc tgtataacat tgtcataaat aaagccctca gtaacaacgc tttcatttat
     5041 ctttgattta tacagacctg taccactaat tcttattaat ctatcgtcaa ctatttcaat
     5101 atctacatct aacacactag ctactgtttc agtgtatttt atcatttctt gttgaaattc
     5161 ttttaattta cttaacatag tttcccccat tagaatttaa tttaccaaat tatcagttta
     5221 gctatatttt aacatatagt cactctttaa aatatatata aaacattact tatttatata
     5281 tttgcgttaa aacagacaat attaatttat aaaaagtttg ttttatatag taaccttaat
     5341 tataatatgc agacaataaa ataaatcaca atacaataat aaaaaaaagc tttcctcata
     5401 taacaaatat atttttgaca taaaaatata cattatatga gaaaagctca atagttaaat
     5461 atttagatag atttttatat agactttttt aatataaact tttttaattg tagacttttt
     5521 ttattagttt ttaattttta ttagttttgt tattggtttt attgttataa tacttataat
     5581 actgccattg cttcaatttc taaaactgca tcttttggta attgagcaac ttgtacacat
     5641 gaccttgctg gtggattttc tttaaaatat gtagcatata cttcattaat atcattaaaa
     5701 tcctttaaat cttttacgaa tactgtagtc ttaaatattt tatccatact tgtaccagct
     5761 tgttctaata ttgcttttac attatctaaa gaagcttttg ttgcttcttt tgggtcagat
     5821 actaactcgc cagtcttcat atctattgga agttgacctg atgtagaaac tatgtttcca
     5881 acttgaattg cttgagaata tggtccaatt gctcctggag ctttctctgt agctattact
     5941 acttttgaca tgacttcacc tcctattatt aagttatatt tacaggaaaa taaaatttcc
     6001 taaacaccaa tattaatacg aacctttaga ttaaacttca aatctaaaac ttcaaataat
     6061 caatacttag atgattatgt ttatttgtgt cttgttaact tttattaaag caattaacgt
     6121 gccaaacttt atttatatat aaaattttgt gaagtcattc aaaatagtta cttctgaatt
     6181 ttttcgtaaa aaaacgctct aaaattactt ttttatgatg tcaatttttt tctcatatct
     6241 agaaatttac caacatgaga attcttgttt tgagaattta cagattaaag ttatttttta
     6301 accttaaatt ctgaacctcc catgactaaa gtcacagggt tcctgcttca tagaattttg
     6361 cataatcaag ttattacata tgaaagaact atagttgaca atcccactat tataaataat
     6421 aaaaccttta cccatacctt atttacccta gttatcatag agcctattga aaatataaca
     6481 gctaaatata ataataacca aaaaattatc aatatctacc actgttgctg aaaatccaaa
     6541 aaactacctt ttgatagtat tacttaacaa tctaattaat ctcataataa atttacaact
     6601 tataaataaa ttgttatatt ggccgtatct caacaacttt ctcctttcct agttttaaat
     6661 cttttataga attgtaccac gtctaagtaa attttcatac tattaagtct tatttctaat
     6721 aaatcattag ctctcattct atgcccaata atgtaagatt gcagtaattt tattgatttt
     6781 aatagtttta tttaatatac ttatattaat tattttcata tgaaattatt atttatatag
     6841 ggggattttt ttaatatgag caaaagtgaa ttaacagcag aaacaacaga agaaatgtta
     6901 gaagtactaa gtggtaaaga ttatgatatt gcatgtcatt tacatgaact tggtaaatca
     6961 ttagattgta aaattgaacc aaaaacaggt gctcgttctt acaaaatagt atattcaact
     7021 aagaaaccaa aacgtagctt atttactatt gaatgtaatg aaaaaaaatg gagagttaaa
     7081 gcaaatcttt ttcatctaaa tacatataaa gatgctgtgg aggaatgctc taaaactatt
     7141 aaagatagta taactaaaac tcgtacttgt aagaaatgta attcaaagtg tattggaggt
     7201 tcttcgtttg aattagatgg aaagtcttac ctgacttgca taggaagtgg tcattatttt
     7261 gcaaatatgg aagaaatgga ttggaaaaac ctagaaaaat taattactaa agaaaataat
     7321 attatgcagg aatctgtata gttttttaag ggtaattatt aaaatatatg agtaacaaca
     7381 gatacttaaa taggcataaa aaaataaagg gtataataag gatatagaat aaaaataaat
     7441 gatatagcac aaagaggctg tctcaaaata cagataagcc tctttttatt gttgaaatga
     7501 taagaatata ttcaatttta tacaatttta tacaaacata ctacgccaac ttacccattt
     7561 catatgcctg tttcattgcc ttacttccct taatatcacc tacattccaa gcacctacac
     7621 catatactat acctttttcc ttagaaccat ttagacatga tgtaaatcct ctaaatcctt
     7681 ctattgttct ttccatatca gccacatttt catctgctgc tgtaacgata aaatagaaat
     7741 ctttatcaca aatttcagta tatctagagc aagttctatc aatcatagtt ttcatttgcg
     7801 cattcatagt ataaaaataa actggagtcg ctaaaacaat cacatctgcc ccaatcattt
     7861 tttcaagaat ttctcccatg tcatctgtct gtgaacaatt tgcttctttt tcataacaag
     7921 caccacatcc agtacaatag ttaatatctt tatcttttaa aaatatcttc tccacttgat
     7981 ttttagattc taatacccct tgtataaact ggtcacacaa taaatcagaa tttccacctt
     8041 ttctaggact agctgatact attaatacat ttttactcat aagatactgc ctccattttc
     8101 ttatttctac tgctctttaa tactttttct ttctcaataa taccttcttc atatctatca
     8161 atcttaaaat ttaatcgttc caaagttttt tgcatttctt ctattctttt tgctagttgg
     8221 tttctctgct ctattaaaag ttcttttcta gctttgatag tactgctccc ttgttgaaac
     8281 atagctacat actcaattaa tgtctcaata gaaagacctg cacctctcat acactttatg
     8341 aaattaaccc actcacaatc ttcttctgta aaagacctaa ttccactttt atttctattt
     8401 acaggtggta ttaaaccaat tcgttcataa tatcgtaaag tatccgctga aagctcgtat
     8461 tttttactaa cttctgaaat cgtcatacat atcttctcct cttgatattg tatagattga
     8521 attatttctc aaaggtttct gctacattct ttaaagcatc tataatttta atgtgttgag
     8581 gacagctttc ttcacattgt ttacattcaa tacaatctga ggcctttcca taagttttag
     8641 tataattatt atagtagacc atctgtgttg aaaatccagt attaagagct tgtttttctg
     8701 cattgtacaa cgcaaaatag tttggaatag cgatattttt tggacagcct tctacacaat
     8761 actgacaggc agtacaagga attaaaattg attcgttgat aatctctact gcttcatcta
     8821 taatattata ttcctcttgt acgaatggtt tgaaattttg catatatcct gtattgtcta
     8881 ataattgttc catatttgac atcccactta agaccatcat aacattatct ttacttgctg
     8941 caaaacgtat tgcccaagat gaaattgaca tatctggatt gtagtcattc aataatttct
     9001 ctgctttttc tggtatcttt gcaagtgtac ctccttttac tggctccata acaattacag
     9061 gcttattatg cttctctgcc acctcgtagc attttctaga ttgtatgctt tcattatccc
     9121 aatctaaata attaatctgt aattgcacga agtctacttc tggatgctca ctcaagactt
     9181 tatccaataa ttctgcacta tcatgaaaag aaaaaccaat attctttatt tttccttctt
     9241 ttttcttttc ttcaataaac ttaaagctat caaatttttt agctacttca taatgtgaca
     9301 cgcctatatt gtgtaaaaga tagtagtcaa aatagtctac accacatttt tctaattgct
     9361 cattaaaaat ggtttcttgc tcttcttttt tctttaaagc cattaatgga agttttgtag
     9421 ctatagtaaa actctctctt ttgtgtcttt ttactagaga ttctctaagt gctatctcac
     9481 tttttcccat gtgatacaca taggccgtat caaaatatgt aaatcccctt tctaaaaaag
     9541 tgtctaccat tttatttaaa tgttccatat caatagttgt aacatcattt tcatctttta
     9601 ttggtaaacg cattaatcca aatcctaatt tttttgcctc cattgtttta cttccccctt
     9661 taaaacttgt ttgttttttc tctctacttt aactattctt acaagtatat aattcttgta
     9721 taattatact ttactacttg gagttaactt caagtcaata gattttttta tttttaagac
     9781 aaatattata aaaatacagt tctttaatat taatccatta catgtttctt tcaccctcca
     9841 attctcaaac ttcacaaact ccaacatgta aagaaatata tactttaaga aattcagtcc
     9901 attaatatta ctacaaatac tttttagata tgtttaaaaa gaaatttcac ctaaaatatt
     9961 tataaaagat ttagaaatag gtcttgtgtc tattttaaaa tatataaaac agtgataaag
    10021 acttatttat aagataaaaa atgaatagtg tatacccttt ttaaaaagtt ttttcctttt
    10081 tatatttgtg atacaatgtt aaatataaaa aggaaaattt tgtattaaag aaatcttatt
    10141 tgttgatttt gtaacttcaa actcagtatc aatttgattt taagattata ttttattaag
    10201 tatgctaaat aacaaatttt taaagattgt gaggtaaaaa tatgaataag aaaaatttag
    10261 ctatattaat atcaggtatg atgttttttt ctagttcttc agcaattttt gcagacaata
    10321 ctacaaagca agaaagatta ataggtaaaa caagatatga aacagcagta gaagtaagta
    10381 aattgggatg ggttcaatca aaaacagcca ttatagttaa tggtaattct attcaaagtg
    10441 cgctttgtgc aaatccattt gctaagctaa agaatgcacc tatactttta gtaaacaaca
    10501 acagtattga aaattcaact aaggctgagc ttaaaaggct tggtgtagat aatgtgtaca
    10561 ttgtagatag tggaaatagc atttcttcta aagtagaaaa tgaaataaaa tcacttaaca
    10621 taaaaataaa taaaatagta ggaaacaata tatatgaaat gtctacaaat gtacttaaag
    10681 aaatagataa gataaaaaag atagaaaatg ttgcagttgt aaatggacta aagggactat
    10741 ctgatgcagt tagtatagct tctccagcag caatacataa tatgcctata atattagtat
    10801 cagatgaaaa cagcaatgat agtagtataa atttcttaaa caataggtct ataaaaaaat
    10861 cttacatagt tggaggaaat aagattttat cagacaatac agtaaagaaa tatccaaaca
    10921 gagaaagaat cagtggttca gatagaaaca atactaatgc aaaaattatt gataaatttt
    10981 ataaagataa aaaaataaat aatgtatttg tagctaaaga tggtattaac caagaaaatg
    11041 cattagtaga ttcattatca ataggagtac tagctgctaa agaaaattct cctataatga
    11101 tatctaatgg tagccttgta aatagtcaaa aagaatttat taaaaataaa gatatagatg
    11161 aaataacaca agtaggagga ggatataatc aaaaagcatt tgaagatatt ttaaaactaa
    11221 aaaatgtgaa cataagaaat aaaactaaaa aaatatcttt aatacaggct aaagaaatat
    11281 taaaacaagc tcttccagga agcaatattt tagtttgtta ttatgatgaa gatgataatg
    11341 aatatgactg caaagttata aaggataata tcctatatga gatagaaatt gatgcctact
    11401 ctggtaaaat aatagaaatt gaaaaagatg atgacttaaa tgataataat ttaggtacac
    11461 aaaatatatc attggataaa gctaagtcta tagcattaga tgctattcct aatggtaatt
    11521 taatctattg taaatatgat gctgaagata acgaatatga ggctaaagta ataaaaaata
    11581 agaaaacata tgaattagag ataagtgcat ttgatggaag aattgtagat attgacatgg
    11641 acaatgattc tgatgatgac tttgatgata atgataagaa taactctaat actaatgaca
    11701 acagttctat tattagtgct gaaaaagcta aatcaataat gctagataaa gtgcctggtg
    11761 ggaaaatagt aaaatttaag tatgatgaag atgacaaaga atatgaaggt gaaataataa
    11821 aaggaaaaac tgaatatgag ataacaatta atgcaattac tggtaaaata ttagaatttg
    11881 aaatagatga ttaataaaaa atataaatag atgattaata aaaaatatat attctattaa
    11941 ttattacaag caataaagcc ataaatattg aaattttcaa tatttatggc tttattttat
    12001 ttttttaatt taaatccaca ttatgccatt atatatatct atgcactctt gtaaaatggg
    12061 ttatatttct ccagtatatt aaaaaaagtg agtgtctcaa aataaatctt ctaactcata
    12121 aagcactctc ctttgtatta aatcaaatat attttcatca tttaaacaat taagaagaga
    12181 cttctctcta ttttgagaca actccatttt aatacactat ttatacataa acatatttta
    12241 aacaactaaa aagcaactaa tatcttaata aatatctcaa tacatatctt cataacacat
    12301 atcaccataa ttacaagcag ataaagaact ctcctcattt aaatacgact caaattcata
    12361 cccaaacaga attgttggtt ctatatatat ttccatatct gtatatctcc atcttcttac
    12421 ctttgcctct ataaccttgt aaaaatcttc taaactatac ccttctttta atcttttatc
    12481 tataagtgcc ttagttatac tcaaatcagc tttaaaattt tttcctgatt cactatttaa
    12541 ttttcttata ataatttcat gtatgctttc tggatttttg taagtagaat cttcagtcaa
    12601 atcttcatcc gaattttcaa aggtattttt atttaaattc tttttattta aattattttt
    12661 taataattct tttttctttg tctcattttc tgtttcatac ccagtatgaa ttatcaaatc
    12721 ataatctttg tctatactct cttgatttat acggctgtat atgttggtat tactgttctt
    12781 aaacaactca tttctatgtt tatatttcat tgttttttgg ttattgttaa tagttgcatc
    12841 aatgtatttc tctatatttt tgaaaatatc accattcttt gttacaattt ctgcattact
    12901 actttcagaa caaacataac tatatacaga acaacaattt ccctttactc ccctacttat
    12961 taatctcaat atacctaaat ctataaattc atttacaagt ctacttattg tagatataga
    13021 tacatcaagg tcagatgcag ctttccttac tgtcatcata aattgtcctc ttggcagagt
    13081 tccttttaat ctttgtatat tttcttttct cattacatag tgattaaacc ttattctatt
    13141 tacatctctt ttttcattaa aatataatac tgctgaattt aattgataaa aactattact
    13201 catattccca ctcctccaat ttaaatatat aatttgttgt aaagttttta gatttttaaa
    13261 taacttatta aatgattatt tttattaaaa agtattcttt gatattttca ttttaaagtt
    13321 ttaagtataa taagttaata gtgtagattt aactttttta tttaaacaat aaacttaata
    13381 ttatttttaa tataaaaatt ttattaaatt tagtatgtaa ttttttaatc ttattttatt
    13441 ccatctatac tcttatgcta agtaataact ttgataatat ttccctaact tatgtttcaa
    13501 ctggtttata ttgcaattta tttaattaca gcttatttgc ataataattc gtccatatca
    13561 taagttgtgt atttatataa atacacaatt aaaaataaat cactatggta tactaattat
    13621 tacgaagact atacttatat gcaaagacaa atataaggca tcttatatct tttatcaatt
    13681 ataaaaaatt aaacgctatc ttatttatca taaattacaa aaacataaaa ttttattact
    13741 atattgctat aaattaattg atacacattt tacacaataa ggagggctat atatgacaaa
    13801 tgctaaaagt aaaaaagaat atctaaatcg tatttgcaaa gtgcaagact atatagaaga
    13861 acatttacat gaacctcttt ctcttgatga actttctaat atagcaggtt tttcaaaatt
    13921 tcattttcat agaatcttca aagcaataga aaaagaaact ttggcacaat atgtaaatag
    13981 gctaaaacta gaaaatgcaa ctgcttttct tattcataga actgacatga ctgttactga
    14041 tattgcacac tacttcggct ttactgattc agcagttttc tcgagagcat ttaaaaatta
    14101 ctataaaata agccctataa aatatagaaa caattatagc aagaattgca aagaaccata
    14161 taaaatttct cagtacaata gaagcatatc aaaacctaaa tgtaagaata ctagagaggt
    14221 taaaggtgaa attgaaattc tagaacttga taatatgaat actatttaca ctagatatac
    14281 tggttcatat ggtaatctaa ccagtacttt cccaaaactt ttagaacggt tattcacata
    14341 tgcaagtgag cagaatctac ttggacttga aaacacacaa atattagcca tttatcatga
    14401 taatccacaa tttacacagg agcatcaatt aaggactagt atttgcatga ccattccaga
    14461 taacattgtt gtcaaagaga atgacaatct tggcaatatg ataatacctt ctggaaaata
    14521 tcttgtggga cattttgata tttcaaaatc tgaatatagt gatgcgtggg attttatgta
    14581 taatgaatgg ctatcaaatg gtaattataa gctacgtgcc tccttccctt ttgaagtata
    14641 tcttaacaac ccacacaatc accctcaaaa tagacacttg gtcgatatat atttacctat
    14701 agaacctttt taataacctc acctaatcta ttcttgtatt aaggattaat atatccctat
    14761 tttacggttt gataaaattg ataaaatgag gtgaaccaat gaaagaaata aaaattaatg
    14821 gagcaaagat acacaatctt aaaaatatag atgtttctat tccaaaagat aagcttgttg
    14881 ttgcaacagg tgtcagtggc tcaggtaagt ctagccttat gtttgacatt gtatttgagg
    14941 aagggcgtaa acaatatctg caatctttag gtatacttgc aggtattgat agtgaagata
    15001 agtttgataa tattcaaggt ttagctccca ctatagctgt tcaacaaaat attattcgcc
    15061 agagcaatcc tcgttcaaca gtaggcacaa gaaccaatat tctcaacatg cttacactat
    15121 tgtattcagt ggaaggtcaa ataatgtgta ctatgtgtga tactcctgta agcgataatc
    15181 taatttgcaa taattgtgga tatgaggaag aacgattaag accaagttat ttctcataca
    15241 actcttcaga tggaatgtgt atgaagtgct ctggacatgg tgcatatttt gagattaata
    15301 ttgaaaaatt agtccttgat aagcatgata ccctaaaaca agtcttagat agagcaaaga
    15361 ttacacctgg atatttgaga gtattttcta aaaaattcaa tgattattta gacatacaat
    15421 tcttacaact acctgaagaa ataagaaatg aagtactcta tggtcattat gaaaatggta
    15481 aaaaaagttc ctctttatca aaggtatttc acaatcgtta caaaaggggc gaagatttaa
    15541 atggagttta tactatgact gcctgttcag attgcaatgg ttttaaaatt ggtgaagaag
    15601 cacgtagagt acttttaaac ggaaaacata ttggagaact tggaaaaatg acgattttag
    15661 aaattgatga tttccttaaa ctcttaataa atcaaggtaa tttaaacaca tttggtacaa
    15721 atcttgtaaa tgatatttta tccaaaactc aacatttaat agaatcacga ttaggtcatc
    15781 tatccttata ccgagaaatg tcaactttga gtggtgggga aatgcaaaga ctatttttaa
    15841 attcacatct cgattcagag atggactcat taatttatgt gcttgatgaa ccaacagctg
    15901 gattgcatga atcagaaaaa atagacatct taaaatcact aaagaaactt aaagatttag
    15961 gcaatacggt catagtagtt gagcatgata aaaacacaat tgaaatggca gaacatatta
    16021 ttgatattgg tccaaaagct ggtgttgaag gtggtcaatt agtatatcaa ggagatttag
    16081 aaggtctact tcaatccgac aaatcactta ctggacagta tctatctgga aaatatccaa
    16141 tgcctaatag aacaagcaat aaaaacatta cacatactga taaaatacct tgtataacta
    16201 ttcaaaatgc aaatacaaat aatcttaaaa atgtaactgt atcattacct ttgggtgcta
    16261 tggttggaat atctggaaaa tcaggtagtg gcaagagttc acttatatca gacaccctac
    16321 ttcctcttct tagaagccaa tttaataacc atactatcaa taatcaaata aattcttcag
    16381 agagtgaaat aggtgaggaa gacgattatg cagttgttga aactattgca gatagactga
    16441 ttggtactaa acatatttct ggatattcag agatatctca atctcctata ggcaaaaata
    16501 tgaactcaac tcctgcttct tatattggta tatgggataa gatacgtaca ctatttgcag
    16561 gtcagccaga atcgttagaa caaggattta cagctggtca tttctcattt aactccaaag
    16621 gggcttgtcc taaatgtagt ggtagtggat atgaaaaggt ctggttggga aataatctaa
    16681 gtatagacca tatatgcagt gaatgtcagg gaaaaagatt taatgatgaa tctttatcta
    16741 ttaaatataa aaataaaaat atacatgata ttttaaatat gagtgtttct gaatctgtac
    16801 atttcttcaa agatattcca aatattgttt cacacttaaa tgtattagaa caaataggta
    16861 tggggtatat aaaattaggc caacctacac cgactttaag tggtggtgaa tcccaaagaa
    16921 tcaaacttgc aaaagaaatt ggtaaaaaac gaaatggtaa tatcctttat gtattggatg
    16981 agccaactac tggtctaagt ctatatgata cttctaagtt gattcaatta ttagatgaat
    17041 tggttgaaaa tggaaattct gtaattgttg ttgaacatga tatagatgta ttaaatgttt
    17101 gtgactggat tgttgagctt ggtccagaag gtggtgacaa aggaggttat ataattgcag
    17161 aaggttctcc aaaaactcta aaagaaaatc caaaatctat aacagggagg tatctttaat
    17221 gaataaaaac aattgcttag acttaatttt tgaaaaagta gacccttcaa gtgttggtat
    17281 gagttcagaa aagctttcac aacttgaacc tttaataatc tcacaatata gcaatataaa
    17341 tggtataatt attgcaagaa aaggaaaaat tgtctttgaa aagtactata atggatataa
    17401 tgctgatgat acttttcatg ttgcatcagt tacaaaaagt attatatcag ccttaatagg
    17461 tattgcaata gataaaggat atataaaaga tgttgaccaa aaggttgttg atttttttcc
    17521 tgaatatact tgtagtcctt ctgaaatatg taaaaaagca gtaactatac gtcacctact
    17581 tacaatgact gcaccatacc cttttaaaaa tatgactgag tctttagaaa gactttgcaa
    17641 acaaaaagat tggataaaat ataccttgaa tcaacttggt caaaaaggcg aaattggtac
    17701 tttcaaatat tcttcagctg gaacgcacct actttcagct attataacaa aaactactgg
    17761 aaaatctgct cgtgaatttg ctaatgagta cttatttaaa cctattggta tgaaagttat
    17821 accagattat gatatgaaag attttggttt tgaagatttc tttggaaaaa atcttaaggg
    17881 ttgggcaaaa gatagacagg gttattctat aggtggctgg ggacttacat tgagtgctag
    17941 agatatgttg cgatttggtt ttctgtattt aaatgatggt atttggaata ataaacgtat
    18001 tatatctaaa tcgtggattg aagaatcagt taaaatgaat agtaatgaat acggttatct
    18061 gtggtggcta tgtaaaaaag atggtgtttt gtggtattca gcaatgggaa ctggaggaaa
    18121 tgctatttgt tgtattccac aatatgactt agtaatagcc ataccatcta aaatagtgtt
    18181 taaacctcgt gatagatggg agttcattga aaaatatata cttacttcta taatagatta
    18241 attactcttt cataaactaa ttactctttc ataaactaat tactctttca taaactaatt
    18301 actcttagat agccaaaccc tccattataa caccagactt ttgtttggtg ttattatgac
    18361 taatactata tatctaaaag gagttgaata ctaatggaca cttacacgac atcagaggta
    18421 gcagatttaa ttggtgtaca tcctaataca gtacgtttat atgaagaact aaacttaata
    18481 cctaaaccta agcgtaatac caatggttat cgtatcttta atgattttca tatagaacaa
    18541 tttagatttg ctcgtacagc cttgaaaatt gaagtggtac aaaggggatt aagaaaagat
    18601 gcccttgaga ttgtaagaac atcagcgaat agggactttg ataaggctat tagtcttgta
    18661 aatcaatact tgcaacaatt agaaatagaa aaatctaatg ccgaggaagc acttactatt
    18721 gttgcacaga ttttaaatgg aaatactcca gaaacaaata aactcttttt aactagaaaa
    18781 gaaactgcag aacacttaaa cgttacaata gatactttaa gaaattggga aatgaatggt
    18841 ttgttaaaag taaaaagaaa acaaaatggt tatcgtgtat atactgatga agatataaaa
    18901 cgacttaaaa ttataagcgc acttcgttgt gcaaactatt ctctttcagc tattttacga
    18961 atgttaaatg ctttatcttc tagtcctaat actaatatta aaactgtcct tgacactcca
    19021 aaagatgatg acgaaattat ctcagtgtgt gacaaactga taacttcatt gaaagaagct
    19081 gaacataatg caaaaaccat gaaatctcat cttcaaatta tgaaaaaaca attttcctag
    19141 ccctccactc taactccaga ctttgatttg tgtgttatcc ttaagagcaa gaaaaattca
    19201 acacacaaat caaaggagga ataggatgga aaataaaaat actaattcta catggaagaa
    19261 aaaagtcatt ctttttttag caagtcaata tatttcctta tttggctcat cacttgtaca
    19321 aatggcaatg atatggtatg tcacacttca gacatcatca ggtgtatggg taacagtttt
    19381 aactgtatgc tcctttatac ctcaaatgat aatttctttt tttgctggtg tatgggcaga
    19441 ctactacaat cgaaaggtac tcataattgt atcagattca acaattgcta tatctacatt
    19501 agttctaatt ctatttatga tgtcatcaaa tggcacaaca agtgaattaa tagccatatc
    19561 agtaatatct gttatacgtt cactaggaag tggtgtacaa acacctgctg taaacgcaat
    19621 gattcctcaa cttgtaccag aagaacattt aatgcgtttt aatggtataa atagtagtct
    19681 acagtctata gtacaattta tagttcctat tgtagctgct gcaatacttg gatttggtaa
    19741 taaaataaat caagttcttt taattgatgt atttactgca attattgcta ttgtattatt
    19801 aatattcatc aaaattccta aacatgatat accaaaacaa actgaaaaag tctcattttt
    19861 tgcagatatg gtatcaggga taaagtactg tttttcagat aagttcatta gaaaagtgct
    19921 ttttacttat ggagcattca tgcttctttg tgttccatca ggatttctta taggacttct
    19981 tattgaacga acatttggca agggttatat atacctgtct attattgaaa tgattggatt
    20041 tttaggtatg gttttaggtg gattgattat aggagttttt ggtggtttta aaaatagaaa
    20101 taagaccttt tttctagcaa tattatccta tgctattttt tcaattattc taggtcttgt
    20161 aacacaagct tggcaatttt ttatatttat gttttttacg aatttttcaa ttccaatcat
    20221 tcaagcatca gctatgacta tgttgcaaga gcatgtagca ccacaaatgc taggtagagt
    20281 tcttagctta cctattatta tatatactgg ttttattcct cttggtatga tgattttcgg
    20341 accaatggca gatgtaattt ctattaataa tttaataatc atagcaggga ttatactttt
    20401 attttttgct ttggctatcc cctattcaaa acaattttac aagcaaggaa tatctaagtc
    20461 aaatgaatcc gagtaatata tttaaatagt ttaactcgat ttatctggtt aaaaatgaag
    20521 gggcttaaaa tggacttttt aatttatgaa gaaaattttt tatatgaaat caaatatatt
    20581 ttatcatttc aacattgaaa aataggttta tctttatttt gagtccctct ctttatagca
    20641 aataatattt tgatactatc tttattaact ttatataata atacctttac ttgtaggtta
    20701 taatgatgaa atttatcaaa tcatataata atacctccat ttatatcata aattaaattt
    20761 atagtacaaa tggaggaaaa taaagtattt atatagttta agtacctatt aagttttcca
    20821 ctaagtagct ctaattgtac tgaacttctt actaaattat attgaataat tataaaataa
    20881 aactaactat tacactacat aaattaaagt atacaaattg cactacataa attacactat
    20941 acaaagtata ttaaatcacc tattaaattg tcccaattat aattatactg agttatctac
    21001 taaaagataa ctttcttttt ttatctaaaa taatatatat cataaaccat actacacaat
    21061 gtacagccaa aattacaata tctttgataa taatgacatt accattaata atctccataa
    21121 taccattaaa tgtagcaact gaaggcatta tatagcataa attccctata ccactggtat
    21181 taacccctag aagatatatt aacaaaggag tacctataaa taaaatcatt actattttaa
    21241 tataaacaat tcctaccata agaccttctg acaactttcc aataaataaa cctataagtg
    21301 atgaaataaa tgctgaaaat acaacgagta acaacatcat tatcatatct aatattgaaa
    21361 tatccaaaca tataaataca gttatcattg aagataaaca cccacataaa agacccaaaa
    21421 atactttttg tataatatac tgacttctac tctgtggcaa aacttcattt ataaatgata
    21481 ttccatcttc tttttccgat ataatattca ttgcattaaa ggtgcatccc ataaacatag
    21541 cagtaattaa aatcatagca ataaaaacat tttgaaactc ttttaaaata ctatctttag
    21601 gcaatattgt aacctcaaca tcttttaaat caccctttag tctaaacatc tctggcaatg
    21661 tctttccaac attttttata gcattaatct catttccata aaacacagtt tttattcctt
    21721 taccatctct aacaactcca attgtgtccg ttttaatatc cttaatttca cgtattaaat
    21781 gcatttttgt gtcatataca cttaccatac catacttctt taaccactgc tctgtttgta
    21841 caggaagtgt atccttcact ataccaaaac gtatctctcc taatgaagat atatcaattg
    21901 ttcccataaa atttattaaa atcgccataa caactggtaa aaagaaggaa attatacaca
    21961 ttttatcttt ttttatactc tttaactggt aacgtaatcc tatcaagatt atccctccct
    22021 aaccaattct ttattaaaaa tatattttac aagtaaaaat agaactatta ttgtcaaaga
    22081 acacactaca aaataaacta attcttttga aaaattcatg aaaaacgcat ttttaagctg
    22141 actataaaca tgatagaagg gatgatattt aatccaatct atttcaaaag atgtatttgc
    22201 agatagaaat ataggtgtag ttatgaatac agcaaccaca agatatataa gagaaaattg
    22261 cttaaaatct ctcaataaca ttgagcatcc tattccaatc aaagacataa taattgataa
    22321 aatactagct tgaactaata cttgtggaag tatttttatt ccttctaaaa atccaatatt
    22381 aaatactact aaaagaactg taaaacatag gtcacatata aaaaaagcaa atatctttga
    22441 taatataaaa agacttcttt ttacaggtaa aataccagta atacgcatta ctcccatctg
    22501 cttttcttta aataataaag aggcaatccc taaaaatcca atagctacaa tttcaaagaa
    22561 taaaatctca caagtcatgt cttttctttg ttttatctca gatgtatcct tatcattaat
    22621 ttgaattatt gcattgttgt ctgatatttt gctattatgg tctttttctg atgataataa
    22681 tgacaatgca tagtcagctc tataattgtc aactccttta atactttcat gtaaaattac
    22741 tttcggctta ctggaactca tatcaataca aactgcactt gtatcttcat caagttttgc
    22801 ttttaattca cctatagaag aaacttgatt aattaatgga gatgcactca tgcttatatt
    22861 ctctggatta tatagatata cattattgtg ataactatct tcatccataa actttacata
    22921 accaaaatta atataacacg aataaagtat gagagagcca agtgtcagca caaaaaattt
    22981 accataaatc atcatccaaa aatctttttt tactaaggta aaaaatttag aatacattac
    23041 actaacatcc ttcctgtgta tttaataaaa acttcttcta gtgtaggttc ttttgaatgt
    23101 acacttaaga tttcatcata tttaaaagtt attccagatt ctaactcttg tatatctaca
    23161 atttcaatat ctcgatttcc attatataca aattccactt caactttatt attgctattt
    23221 ttcattttta aatttttggg tttatctatt accataatct ttccatctgc aataaaagcc
    23281 acattgttac acattaaatc tgcatctagc atattatgag tagtcaaaaa gatagttgtt
    23341 cctttttttc gttcttcttc aataatctta cgaaatagta cagctccaga tgggtcaagt
    23401 ccactagtag gctcatctaa aaataacaac tttggattac ttaccaatgc tcttgccatg
    23461 ctaatacgtt gcttcatacc ttttgagtag gatgatacag gcttatttat aaactctttc
    23521 ttaaactcta acaaatctaa gagttcatat atgtctctcc tttgattttt aggataaaaa
    23581 gacgaaaaat attctaaatt atcaattgca cttaaattgg tatataaata aggaaattca
    23641 aataaaacac caatcttttg atataaagat tctgtgtatg ctttaacttc cttaccaaaa
    23701 atggatacgt gaccattgta accttttaaa acaccattta agattttctg tgttgtggat
    23761 tttcctgaac cattaggtcc aaggaatcca aagatttctc cttcttttac ttcaaaatta
    23821 agtccatgca atatctgttt atcttttcca taagaaaatt ttaactctct tacttttatc
    23881 atctatcata acctccttta tcattttttt gtcgtctatc ccaccatttt ataaatttaa
    23941 ttttaagcgg aatagaaagc aatattatca atataatagt caaccatgta taccatttca
    24001 taagtactcc cccttgtaac cttatttaat tacgcttcta ttttttaatt tatttaacct
    24061 attttatttc tatttggtga aatcagagtg tctctcttgt gaaatcgaag tgaaataata
    24121 aaaagcttaa taaaaaatct tgttttcatc aggaaaacaa gactttttat taagcttttc
    24181 attaagcttt ttattagact ttttcattaa gctttttcat taagtttttt tattttattc
    24241 tctttaaata cttacgtata caaataaaaa tattttacat cagatactta taatttataa
    24301 attaatacta aattattcat caattggaat cataaaataa aactctactc ctctatcacg
    24361 attattcact ccatattcta acccttgcat tgtaagtatt tgtgaaacaa ttgcaagccc
    24421 tagacctgaa cctcctgtac gctgagattg aacactacga taaaacttag accaaatctt
    24481 tgaaatctca tcttgctcta taaacctacc atcattataa atttcaaata aaagcaagcc
    24541 attttcacat gtaatcgata aatctaaatt accattatat acaacatgct tctttgcatt
    24601 aataactaga ttctctacta cttgttccat tctcatttta tctgccacta caaaaacttc
    24661 atactctggc aaatcatatg taaaataaaa attggcatct ggtatatcaa ttaaaagacg
    24721 acctgccaca gtttcaacaa actctataaa atcaaaacgc tctgggttaa gtttagaaac
    24781 tcctgcttcc aatgcagata agtctaataa tgatacaatc atattgttca ttctatcagt
    24841 ttcttctatt ataacattca tataattttt ctttttttct tcatcaactt catctataag
    24901 cccctctgta tacgcacgta taatgccaag tggagtcttc atttcatgtg aaattgtatc
    24961 taccaactcc tttctttgtt ccaatagcat tctttcctta tttacatcct tttcaagttg
    25021 aatatttgca ctttctaggt ctgataatgc ctgttgtaga tttgtagaca ttgtattcag
    25081 gctcctagaa agttctccaa attcatcatt agtatttaca gtacatggat tagaaaaatc
    25141 aagttgggac atactttttg cagatttatt tatagatgtg attggttctg aaataaattt
    25201 tcccaataag aaatcaatac tcataataaa tataaccagt attataaacc aaatccaaaa
    25261 ttcaaattta gagtttatcg aaaattcttc aacaaccaga taaaataata taattaacgc
    25321 tcctgataat ttagaaagta aaaacacttt ttttctaact gaatatagtc caaaattttg
    25381 tttaatccaa tttgaaatat ctacattttt cagtttttct ataatctttc ttaaactatt
    25441 cattccttaa cctcaaactt atatcctgaa cgaattaatg taactatatg gtgtccttca
    25501 ctaccaagct ttttgcgtaa ggtttttata tgtgtatcta cagttcgtgt gtttccttca
    25561 aaatcatatc cccatataca atttaaaagt ttctctctgg aaaaaacttg attagggttt
    25621 tccataaata aacgcaataa ttcaaattct ttatatgtta aatcaatcaa tttatcttct
    25681 acatacactt gtcttgatgc taccataata aaaatctttc ctaaactcaa tgaatttttg
    25741 ggaatatcag tagtgtatct acgtaacaaa gcattaactt ttgctaaaag tacttttggg
    25801 ctaaatggtt ttgttatata atcatctgcg ccatattcat aaccctttaa tttatcctcc
    25861 tcttcacctt tagctgtcaa tataataata ggtatattag tcatttcacg tgaaactcta
    25921 cacactgaaa atccatctaa atacggcatc ataatatcca atatcattaa atctatattg
    25981 ttgctcttta atattgtaag tgcctcgact ccatcatcag cagttataca agtatatcct
    26041 cccttttgca tatattctac aataatattt tgcattcttt tttcatcttc tacaactagt
    26101 attttagcca tttctattta tcacctcttt tttgtaggct ttattttagt ttatattaat
    26161 ttatttattt ttcaactatt tttttatagt attttttata gcattttgat agtatttttt
    26221 agactattct taatggaatt gatatcatag ataaaaatag cctactaact ttttctatgt
    26281 tagcaggcta aaatatttct aataataatt atattatttt gtcactattc tattttttcg
    26341 attaaaatat attctaaagc aaatatcttc aattaatgaa taaattgcac ttgttataaa
    26401 gtacagacct atggctactg gagttctaac agttagtata agacttgtta tggtagtcac
    26461 cacagccatt tgtttgttaa actttacttg agaatttatt tttaaatatg gtatataatt
    26521 cactaaattt gaagctaaca taattaatgt atatatacaa ggtaatataa acaaattatc
    26581 aaatgtacct aaattagcaa tccatggaat tataattgtt gtaaattcct ttgtcatatc
    26641 taaacataca tgatataaag catatactac tggcatttga accaaaacta taagacatcc
    26701 cagcatactc ttcatacttt ctacagaact tacttgtatt tgcttttcca attctttagt
    26761 atcattctta tacttttctt ttatatattc cattttttca gctaattctt gctgtttttt
    26821 tacagaaaat ctttgtttta atgatagtgg cataagtact aatttaacta ttaaagttat
    26881 aagtacaata gaaattccaa aatcacctgt aaaattaaat aatatactta ataatccttg
    26941 caatatactt gaaatgaaat ccattttatt ctctcctttt tatttttaaa ctttagaatt
    27001 tataatagat tcatttcaaa ttaaaacaaa ctacaatacc tccaaatatc atatttctga
    27061 aaaactatat actgtttagg cagtcgttct tcagaatatg taattctatt tacaaatatg
    27121 tctcttatta aaacatactt aattttatga tttaagaggt ctttacaaaa ataaaatata
    27181 cttccaatga tagataccaa taatgtcata taaattagta catataacat actatccata
    27241 tctaatctca tcacatcacc tcttcatcac ttgtatttat ttttagacaa tttcaagtcc
    27301 taaataattc caacatttat atttagtttt aaataattat agtatagaaa actccta
//
LOCUS       DAMJVG010000051        27343 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.051, whole genome shotgun sequence.
ACCESSION   DAMJVG010000051 DAMJVG010000000
VERSION     DAMJVG010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27343)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27343)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27343
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.051"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            551..1258
                     /locus_tag="PC512_002375"
     CDS             551..1258
                     /locus_tag="PC512_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDF2442113.1"
                     /translation="MIFTKSNKYDKDFLMKNMMGPNCIKILEELTSKIKLEKGMRILD
                     LGCGKGISSIFLAKEFDATVFATDLWIEPTENYKRFKEFKLDDKIFPIQAEAHELPYA
                     EGFFDAVISIDSYHYFGNKEGFLDNHISPLVKEGGILAMAMPGLKEDFVDCIPDELIP
                     FWQDNMNFHSITWWNKLWSESESVIVEKCEALNCHDEAWKDWINCDNSYAINDKKMME
                     VENGKYFNTISLIARTK"
     gene            1857..2357
                     /locus_tag="PC512_002376"
     CDS             1857..2357
                     /locus_tag="PC512_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2442114.1"
                     /translation="MIEGIKFIKAEEKYIYSYWQTFDKIAKERKYLAMDEAFPFEETV
                     EFIKNIINKNLPQLFIIDLESDNCIGWCDVLPKTEKVGYLGMGILKEYREKGIGSNLL
                     KQIIDLSKEYGYEKIELDVFKSNSRAIHVYKSLGFVEVNTISSGFTWNDRPVKEEVIQ
                     MELTLI"
     gene            complement(2607..3386)
                     /locus_tag="PC512_002377"
     CDS             complement(2607..3386)
                     /locus_tag="PC512_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442115.1"
                     /translation="MNKNILNNSFPEVPESFHNSLSKTLNSLPEREENYKMINNKTHK
                     LPFRKGLVATLAITLILSTTALAVGHIYSLVGKSSTKATYTSIPTTEQVKKDFNFTPN
                     IVSEFSNGYKFKGAYTVNKKAFDKENNVLGKSKALSFEYKNGNDEISLDTANNVLGKS
                     SDNLKVVDTYKDINISYEAFAQKFVPEGYKMTEQDKIDEKSGKYTFSVGPNNESDKVE
                     VNKFKFLTWKQDGVYYSFTVQDSNLSMNDLVKMAHEVIDAK"
     gene            complement(3383..3862)
                     /locus_tag="PC512_002378"
     CDS             complement(3383..3862)
                     /locus_tag="PC512_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF2442116.1"
                     /translation="MDKTTFTNNILESEQTLYRVSKSILGNDQDCEDAVNNAILKAYE
                     KLDSLKEEQYFKTWLIRIVINECNSLRRKRLKSLSFEDVFKNKKIDEKDDYSDLYTAI
                     QSLPKKIKIPIVLYYIEGYSVDEVKEILDIPQGTVKSRLSRGRRLLKTKLENTEVII"
     gene            4848..5855
                     /locus_tag="PC512_002379"
     CDS             4848..5855
                     /locus_tag="PC512_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HDF2442117.1"
                     /translation="MGKYQDSKKVVRNYFEALENATGDEVENVLKQHMKSDYNWKGVY
                     PFREQEGTENVADVFWKPLKKSLSNMQRRQDIFIAGTNEIDNSEWVMSMGHFMGLFDN
                     DWLGIKHTRKMISLRYAEFNCVQDGKIAKTGLFVDIIGFMIQAGVNPLPPQTGSYFVY
                     PGPIDHNGLLFEDADEVEGVKTLALVNKMVDDLSELNESGAMGCPPEILEKSWAKDMI
                     WYGPGGIGASYTIPRYQEQHQLPFRNNLKGKTFNGHVCRFAEGNFACFFGWPNLTNVP
                     CGGFLGLPGGEVKADMQVVDVYYRKGDKLQENWVLIDIPYWLKQQGLDILERTKSIFN
                     A"
     gene            5893..7320
                     /locus_tag="PC512_002380"
     CDS             5893..7320
                     /locus_tag="PC512_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ester cyclase"
                     /protein_id="HDF2442118.1"
                     /translation="MASTNKNNATSKEEEKEVSTSGLESCTVKENKAKMNQTNFSNIN
                     ENQTNENKTNTYKRNIDKGNIDKGNIDKTNTNKSDINKVNIDTVDTDKLNTNTLTKKN
                     KKVIFKGEDNMSSTKIYYGDSLEVTPVGVMDYNDFSKQTKREQEIPGFDSKYRDFVDY
                     IMKITHNIWEEKGIGVIYDTYHNNVTMHCGSSNLVGIKDVISNTLQTLHAFPDRRLIG
                     QNVIWSNFGADGFLSSHRVLSTATNLGDSNFGPATGRKINFRTVIDCATTNNRIHEEW
                     LVRDNLWIVTQLGLNPQEVAKSMAKASESKVLSLQSTYGICESMDGQFMPTKYQAKDD
                     SAGEMMLEMTSRIYNYKYINEVKKYYHDNAVVHFICDKDLNGYDEIQGMIVSLLASIP
                     NGSYEVERVTCNQREKNEGYDVSVRWRLRGINEGIGFFGQPSGKHIEVMGINHYHILQ
                     GKVKEEWITFDGMDVLKQMYMGVEE"
     gene            7462..8727
                     /locus_tag="PC512_002381"
     CDS             7462..8727
                     /locus_tag="PC512_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2442119.1"
                     /translation="MKTTVEIENDIILGKDYSNLKRGIAFFSIALIYFFYCYNFMVGT
                     FIKPTMIYALADGGFGFSLKQTEEIFAVMSFGTIPGTFIFGVISTKIGKKRTLISVAL
                     LIGLTTFIPMLSPTNIMLWKIARLCTGVVLGGVFGTAMPLVADMFPSKYRGKLAAILT
                     ALFSLAMIFGGKVYGVLGDANWQILMYTAIIPPIVGAILAIFFVPDDLEYTKELVKKG
                     KETGEKISYISMYKGKYLWIGLGTILLSGANFTAYSAFSNNATTYLVTRIGMSAAVAG
                     SIYSLQGIGQLVGYLFWGSIADKFGRKIPFIGMALAAVFVFIYTKLGGDNTTTFYMIS
                     VLLGVAVGYSGAWGAYYTELFPSKYRSLSSGMSFNGGRIISTFAIPAIAGTASGTLGM
                     MTIFYISIAVFVAGAIVWLFLPETLNNKK"
     gene            8769..10367
                     /locus_tag="PC512_002382"
     CDS             8769..10367
                     /locus_tag="PC512_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HDF2442120.1"
                     /translation="MISSIDVCIIIGYLLLMLVIGYYSGKDNKNQEDYFLAGRSMPWI
                     PIALSVAATMISANGFIGGPGWAYVDGMYPVMVNITVPLAIFFALSITTPVIYKLKIT
                     SIYEYMGLRLGNYSRGLTIIQFFINSLIQASSMVYIPVLIIQMITGWSLYALVPIVVL
                     VSIIYTLLGGIKAVIWTDSIQMIVVISAVFIVIIVALKGMNLSFFDTLQIAQQSGKLN
                     TFDFSRDISVTNTFWATLIGGTVMWIRYFCFDQSQVQRVLTSKSLKCAKNSFVVSAFV
                     MNLVYYFMLLVGVILFVFYGGRTFETSNEIMITFILNELPVGAIGIIIAGVFAAAMSS
                     IDSILNSMTTVFTKDIYEFYFKKDNKESSLKVTMIITVVIGVVMTGFIIMGFGGSIKS
                     ILDLVGNYISYFAGPATGAFVLAMFTYKANDKGVSIGFIVGLVLGFFISNKYNVSWLW
                     NPAIGATITLIFGYIFSVILKKNHNADDIKKYTAFGMRNHLISQGMDKVDGVSIVPFS
                     LGKQELIVLAFFIIQYIILFLIQF"
     gene            10402..11424
                     /locus_tag="PC512_002383"
     CDS             10402..11424
                     /locus_tag="PC512_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDF2442121.1"
                     /translation="MNQKKVHYNKSATSKDVARLAGVSQSSVSRAFGSANGKGVKPEV
                     RERIFRVANEIGYVPNLVARGMISGKTNVIGLIVGDSLGPFYNRIINLFVEKIQEIGK
                     QCLVFKVPRQQSIDSIISKVIQFQVEAVIITASAMNKVMAETCEENNIPVILFNRFIP
                     GIKISTVYVDPIEGGGMAAEYLLKKGHKNIGYIQFTRETSEEMEKKIGFYSKLRQSGI
                     HNLKEESANYDYDSGYEAGKRMLALSNPPTAIFCTSDLIAIGVMDAARFEYKLRVPED
                     LSVIGYDDIQMASWKSYNLTTIRQPLDLLIEKTINILKSLLNEENPESVVEMLKPELI
                     ERGSTL"
     gene            complement(11812..13215)
                     /locus_tag="PC512_002384"
     CDS             complement(11812..13215)
                     /locus_tag="PC512_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2442122.1"
                     /translation="MKMLNNFFKKINNPAPVFAQTKMERDNQTDDSLSTKPKTTFRDV
                     AGLDEVKEELFEIVDFMKSPQKYQKMGAKIPKGVLFYGPPGTGKTLLASAVAGETNSS
                     FFNVTGSEFVEKYVGVGAKRVRTLFEKARKEAPSIIFIDEIDAVGAKRHLESNNEKDQ
                     TLNQLLVEMDGFNKDSNVLIIGATNRLDLLDEALLRPGRFDRHIHIGAPNYHTRFEIL
                     KVHTDDKPIDKSVNLELLAKKTHGFNGAHLSNIANEAAIFAVRDDSECITSEHFDKAL
                     ERVIAGLESKNSALVEKEKKIVAYHEAGHALVSDIVGICPIQKISIVPRGQALGYVLQ
                     LPDEDRYIYTKDELIGKIKILLAGKASEELIFNHKSTGAKDDLKKVTEIANQMVCEYG
                     MSNLGFMTIDGNDKTFLCDKVQKEANRIVEICYKETLEMLKDNLEDLHSVSKFLFEKE
                     TMTHEELKDLIGKEAVN"
     gene            14082..14591
                     /locus_tag="PC512_002385"
     CDS             14082..14591
                     /locus_tag="PC512_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HDF2442123.1"
                     /translation="MSKELAINEQIKDKEIRVLSPTGEQLGVMPTKEAQAMANSKNLD
                     LVQISSNANPPVCKIMDYGKFRYEQARKEKEAKKKQKTIVVKEVRLRPGIEQNDLNTK
                     ANNAIKFLKKGDKVKVELRFRGRELGHKDIGKEVMLKFLDIIKEFGEPTKAPAFEGNN
                     MVVIIDPKK"
     gene            14619..14813
                     /gene="rpmI"
                     /locus_tag="PC512_002386"
     CDS             14619..14813
                     /gene="rpmI"
                     /locus_tag="PC512_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HDF2442124.1"
                     /translation="MPKMKTHRGAAKRLKKTGTGKLKRAKAFKKHILTKKSAKTKMNL
                     RKSTLVSDGDAKRIAQLLPY"
     gene            14869..15225
                     /gene="rplT"
                     /locus_tag="PC512_002387"
     CDS             14869..15225
                     /gene="rplT"
                     /locus_tag="PC512_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HDF2442125.1"
                     /translation="MARVKKAMNARKKHKKILKLAKGFRGSRSKLYRPANTFVMKALK
                     NAYIGRKLKKRDFRKLWIQRINAAARMNGISYSRLMNGLKLSGIEVNRKMLSEMAIQD
                     PEGFAKLAEVAKAKLA"
     gene            15535..16080
                     /locus_tag="PC512_002388"
     CDS             15535..16080
                     /locus_tag="PC512_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442126.1"
                     /translation="MNEKLMDCFVNPIKCKLLIEIFSNNRTTAKQLGEKFQDISKATL
                     YRYLNKMLKDDIIKVVEENKIRGTVEKVYAMKLDIADDVNKIIDENSGEEYAQLFTQY
                     MMGFLREFYEYAERKEKDILKDGSGFSVCPVYASIDEIVEVSKKIASILEPLRNNSHE
                     EGRRMHSIGVIITPPKEDEGK"
     gene            16067..16231
                     /locus_tag="PC512_002389"
     CDS             16067..16231
                     /locus_tag="PC512_002389"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442127.1"
                     /translation="MKGNKSDLHEVEPIYTENRFMIYICIQSKVSLLGLYFIVSFHLS
                     NDLEWYNEVF"
     gene            16520..18445
                     /locus_tag="PC512_002390"
     CDS             16520..18445
                     /locus_tag="PC512_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDF2442128.1"
                     /translation="MKIKFVIMPLVIFLMVLFVGCQSTKDTEVKAKYTEIKILGTGDL
                     HSILTDSMVSYVNEEREKNKNLLMVDAGDFYGTQSREMWEWSSGKKLINIKRNGRAEY
                     DDIIKSSKDEVPIVKDMAKLKYDAVVLGDNEFVSNDKQSLDKLVSDFKNNNMPLVSAN
                     IYEQSGENYVQPYVMKNIKTDEGNVKVGILGLTIKEVGETLGLEDFEKDKKARELGEQ
                     ADYKGKLYANDLVEDAKKWIKVMEKESPDIIVAVVHSGEEPKTDRNPGNRIKELATTV
                     DGIDAIVAGHTHEKIDEHKYKNKSGDEVIVTQPGWHGDRVSEINFKLNKENGKWDIKE
                     KSSKLKIIDKEVSIVATADLHSHFSDKLTVDLVNERSNPIEPVVVDAGDFLDPQTDEM
                     TQWYKEWKSIRDNNSDKTISRCPMVMDMNQGMYDAVVLGNHEFVSEKDEFWSDERLLD
                     AVIEDFEQVAISVLSANIYRQSGKNYVKPYIIKDVETSEGNVKVGILGLTIKEVGKGL
                     KNVNLQEQFQYKDKLYANDLVEDAKKWVKVMKKKKPDIIVAVVHSGEEPKNPKHPGNR
                     IKELATTVDGIDAIVASHTHEKIDEHEYKNKSGEKVIVTQPGEHGKYYSKITFKVNKE
                     KGSWIINDKFSKTIEVE"
     gene            18846..20750
                     /locus_tag="PC512_002391"
     CDS             18846..20750
                     /locus_tag="PC512_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDF2442129.1"
                     /translation="MKIKFIIVASIIFLIVLLVGCQSTKDTEINVLATSDLHSIIPDN
                     LISYVEEERKYDENLLMVDAGDFFDMQSGEMNKWFTGQKLVRFKDGIPEYKKIAEPRE
                     GEVPLAKKMAKLKYDAVTFGNHEFVSNDKQSLDKLVSDFKNNNIPLVSANVYEQSGEN
                     YVKPYVMKNINTDKGTVKVGILGLTIKEVGERSRFKSFEQDKKARELGEQPQYKGKLY
                     ANDLVEDANKWVKVMEKKEKPDIIVAIVHSGEEPKNPKNPGNRIKELATTVEGIDAIV
                     AGHTHEKIEQHTYKNNSGEEVIVTQPGAHGNSISKINFKLDKKNDKWFIKDKYSELKI
                     FGKEVNIITTSSLNPKFSDEMAVNLFNERDRDVQPIFIDTGDFLNTNTKEMTKWAKEW
                     QYNENKGIYKKINEWPIVYLGYDAVVLGSHEFTEDKETFEEKKSTLDYIIENFEEMKI
                     PVLSANIYDESGENYVKPYIIHNVETREGNIKVGVLGLTTTDKDEEDLSSSSLSKDSK
                     TSKIPEETGKLYTNNLVKDASEWVKVMQKESPDVIVAVVHSDNNSTLKNPSSEVKKLA
                     MSVDGIDAIVVGHTKNKVEEHIYKNKSGDEVIVTQSGEDCYSKISLELRKENGKWNII
                     NKYSKAIKMK"
     gene            21020..21799
                     /locus_tag="PC512_002392"
     CDS             21020..21799
                     /locus_tag="PC512_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HDF2442130.1"
                     /translation="MSYKKIAIITGANSGFGKEFLKLLINEEEITEIWAVARNKARLN
                     QLVDEFGSKVKIFSKDLSKIEEVKEIGTFLSKENVCIKYLINNAGFAKFCSYNDLSID
                     ESINMIDLNISAVVALGLICIPYMQKGSHIMNISSQASFQPLPYQNIYSSTKAFIRNY
                     TRALNVELKSKGINAIAVCPGWMSTNLFKRGIVVAEKGTKNFPGIVSPDIVAKKALKD
                     AKKNKDISVYGINTKSSHLLAKLLPQKMMMKVWLMQQHIKE"
     gene            complement(22109..22930)
                     /locus_tag="PC512_002393"
     CDS             complement(22109..22930)
                     /locus_tag="PC512_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002572585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallohydrolase"
                     /protein_id="HDF2442131.1"
                     /translation="MKLKIVGSGGMSIIPSSFCKCKICEEARQKGGRYERLGPSLYID
                     DIKMLIDTPEDIAVACNRQKISEVKHISISHHDPDHVKGIRIVEKIGCDFITGENNPI
                     GFYALPEVIEDINRTNLDCLKYYGNVINCISINETSHVKINNFDIDLINNNPDRNITF
                     YVIKENEKKVIYACCNPKPFTHSDMYFDADVLIISLVSDDGILNDGTKLKDTPFKDEI
                     FTLDEIVEIKNYYRIKKIIITHIDEIWGKSYGYYSELEKKLDNIYFAYDGMEIIV"
     gene            complement(23605..24423)
                     /locus_tag="PC512_002394"
     CDS             complement(23605..24423)
                     /locus_tag="PC512_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2442132.1"
                     /translation="MFKIGDFSKLSKISIRMLRHYDEIGLLTPSHTNKTNGYRYYSAD
                     QLSTTNRIHALKDMGFGLYSIKEILTEYNDKESLIKYLNIHHSQVKEQLEDTQKKLLK
                     IETTIKRIGGNDIMKNYDVTIKNFAPKYMMTLRRVIPTYQDEGMLWHQVFLETKDQNV
                     QIEPPKYSKAVFYDTGYKEDYVDVEVQVAVSGKYKDTEHVKFKTVPSVTAATAIVNGN
                     FNQVADACEAIGNWISDNNYDVDGPMFNIYHVSPGNDSNPDNWVTEVCFPVKKK"
     gene            24591..25172
                     /locus_tag="PC512_002395"
     CDS             24591..25172
                     /locus_tag="PC512_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2442133.1"
                     /translation="MKSNDKDARERIIEVTLNLLNEVDDIEEITVRKIAERANVGVGL
                     INYHFKTKDNLLSTAIGDVMSNIIAELYDDSVYTLRPIEDLKNLLKKLCDTGLHYEKV
                     LPFVLNQCITNGDMQAELDIVPMLRKIFGNKKDEMSLRIIALQIILPIQISALSTESF
                     QLYSGINIKNKYERDKFIDILIENIIGEDVDVR"
     gene            25169..25363
                     /locus_tag="PC512_002396"
     CDS             25169..25363
                     /locus_tag="PC512_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442134.1"
                     /translation="MKIITIGSSLITVLLFLSTMVCGFWIKNNKVTDASSIKFHMNSA
                     IFTGIFLLISTILLIIYIKK"
     gene            complement(25527..27269)
                     /locus_tag="PC512_002397"
     CDS             complement(25527..27269)
                     /locus_tag="PC512_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M3"
                     /protein_id="HDF2442135.1"
                     /translation="MVKSKKKIFVFLILIAVFIIFASYIRNYTNDTKKDSVRGTIPFE
                     KMEYKRPNIQSICENINKCNDKLLTAKTAKEQLNLFNEVDKIYQDFYSTLTIAKIRNN
                     IDSSDEFYSKEYKYLMSKSVDVDMSYKDFQDRFVTSKFSKELEKELGKDTFNYLKNIG
                     KLNSKEVEGLLKKEQDLVVKYEDLLAKSTVSIDGIEVDFEEALSRPNLSPEEYVKIYS
                     DYLKKYNPIFGNIFLELIQTRTEIASKQGFKNYIDYAYMNLNKDYSQEEAKKFRQDVK
                     DYIVPLYREISSKPSDSSIYIKVYKNRSFRKFDKVLEDISPKLKESFDYMKKYDLYDY
                     SSGKNKSPGGYTTYINKYKAPFLFNTWDNSFLGVTSFAHEFGHFYNYYNSINLNNKMQ
                     PSIDVCEVHSTSLEILFYKYFDDFFGKQSEAIKKEHLSIVLNTIIDACLYDEFQEIIY
                     KNPYMSLNDINKLFFDLEEEYGVSNNILREKNAPFWILVSHNFQVPFYYLSYGLASDV
                     SLQIWQLSQEDYRKAVDVYMDFLNQNTDAGFKDVVEKVNLQLPFQNGNLEEISSTLYD
                     YFGIDNPLELKNAS"
BASE COUNT        10303 a         3125 c         4558 g         9357 t
ORIGIN      
        1 taaagtgtca aatatgcact aaattaaata agttaattag tatataggtt aaagtggaag
       61 taattaaaac ttattaagta ttagaaaatg acttcttatt agagtaagta tctaaaatga
      121 tataaaaatt atgattactc attaaagtga ctattataga gtggataaga ttactcatta
      181 aagcgattac tgtggagtag ataaaattac tcactaaaat aactatcata gagtggataa
      241 gattactcat taaagcgatt actgtagagt agataaaatt actcactaaa ataattatca
      301 tagagtggat aagattactc attaaagcga ttgctgtgga gtagataaaa ttactcacta
      361 aaataactat cacagtagat aagattattc attaaagtta ctatcacaga gtggataaaa
      421 ttacacatta aaattgtctg ttaaagaatg aataaaaaag agattgctca atataagaag
      481 catataaaaa ataaaaaatc aaacgtataa aatttaataa ataataactg atagggaaag
      541 gaaagataga atgatattta caaaaagtaa taaatacgat aaggactttc tcatgaaaaa
      601 tatgatggga cctaattgta taaaaatatt ggaagaatta acaagtaaga taaaactaga
      661 aaagggaatg cgtattttag acttaggttg tggtaaaggt atatcttcga tatttttagc
      721 aaaggaattt gatgctactg tatttgcaac agatttatgg atagaaccaa ctgaaaacta
      781 taaaagattt aaagagttta aattggatga taaaatattt ccaatacagg cagaggcaca
      841 tgaactacct tatgcagaag gtttctttga tgcggtgata agtatcgatt cttatcacta
      901 ttttggaaac aaagaaggat ttttagacaa tcatatatca cctcttgtaa aagagggggg
      961 aatacttgct atggcaatgc ctggattaaa agaagatttc gtggattgta taccagatga
     1021 actcattcca ttttggcaag ataatatgaa cttccattca attacatggt ggaataaact
     1081 ttggtctgaa tcggagtctg tgattgtaga gaaatgtgaa gctttaaatt gtcatgatga
     1141 agcttggaag gattggataa attgtgataa ttcatatgct ataaatgaca aaaaaatgat
     1201 ggaagtagag aatggaaagt attttaatac aatttctttg atagcgagaa ctaaataatt
     1261 gtgatgaatt tataaaagta taagataagt agaaatataa gttgaatgag agtataagaa
     1321 gcatagaaat ataagttgaa ttaaagtaga aggtaaataa aaatgtaagt taaataaaga
     1381 gtttatacaa aaatgatttt ttagattatt tatacccaat cgagttgctt aggtcagttg
     1441 ggtattttta ttttttaaag ttaaattgca aatactattg tgtgatatat attttaatac
     1501 taaatgtttg ttttataaga aataaactaa tagaaaaaat agttttaaca atgaaagcaa
     1561 aaaaggtatt gatgaagatt aaaaatttta tagtaccatt ttatatattt tattatactt
     1621 taaatcaaat ttcaaaatga ttaagtatat atacccaaaa gattaaagaa ctatatttat
     1681 tatactatta aaaattattt taatagagat acaagagata gatatattgg ttttaatttt
     1741 atagaaatat acaaagatat tttaagctaa tatatagtaa tttatatagc attataaaat
     1801 agaatcatat aaaataagtt aactacaatc aaaaattaaa aaggggaaat gttaagttga
     1861 tagaaggcat aaaatttata aaggcagaag aaaagtatat ttattcgtat tggcaaactt
     1921 ttgataaaat agcaaaagag aggaaatatc tagctatgga tgaagccttt ccttttgaag
     1981 aaacagttga atttataaaa aatattataa ataaaaactt accacaactg tttataattg
     2041 atttagaatc agataactgt attggttggt gtgacgtttt acctaaaact gaaaaagttg
     2101 gttatttagg catgggtatt cttaaagagt atagggaaaa aggtatcgga agtaatcttt
     2161 taaaacaaat tattgattta tcaaaagaat atgggtatga aaaaattgag cttgatgtat
     2221 ttaaaagtaa tagtagagct attcatgttt ataaatcttt agggtttgta gaggtaaata
     2281 caatatctag tggttttaca tggaatgata gacctgtaaa agaagaagta attcaaatgg
     2341 agcttacact tatataaaat aaagttaaag tctttaaaat tccatataca cttgtataaa
     2401 ataaagttaa agcccttaaa attccatata aaagaaatat ttttaagggc tttttaataa
     2461 tgcttctttt gaaggtagct aaatatctaa aattttatat attaaattta aagaaaatat
     2521 aaagatggaa gatacaacca tgtttactaa taaaaaaatt aaagtcataa ataataaact
     2581 cataaacaac ttattattac ttatgtttat tttgcatcta ttacttcatg agccatttta
     2641 actaagtcat tcatagataa atttgagtct tgaactgtaa aagaatagta aactccatct
     2701 tgtttccatg tcaaaaactt aaatttatta acttcaactt tgtctgattc attatttggc
     2761 cctacactaa atgtgtattt gcctgatttt tcatcaattt tatcctgttc tgtcatttta
     2821 taaccttctg gtacaaactt ttgtgcgaat gcttcataag aaatattaat atctttgtaa
     2881 gtatctacaa cttttagatt gtcagaactc ttcccaagta cattatttgc tgtgtcaaga
     2941 gatatttcat cattgccatt tttatattca aaactaagtg cttttgattt tcctaaaaca
     3001 ttattttctt tgtcaaatgc ttttttattt acagtatatg ctcctttaaa tttatatcca
     3061 ttactaaatt cagaaactat attaggggta aagttaaagt ctttttttac ttgttctgta
     3121 gttgggatag atgtataggt agccttagta cttgattttc caaccaaact atatatatgt
     3181 cctactgcaa gggctgttgt gctcaatatc aaagtaatgg ctaaagttgc aactaagcct
     3241 tttctaaatg gtaatttgtg tgttttatta ttaatcattt tataattttc ctctctttct
     3301 ggtaaactat ttagtgtttt gcttaaacta ttatgaaaac tttctggaac ttctggaaac
     3361 gaattattta atatattttt attcatatga ttacctccgt gttttctaat ttagttttta
     3421 ataatcttct tcctcttgat aatctacttt ttacagttcc ttgaggtata tctaatattt
     3481 ccttaacttc atctactgaa taaccttcaa tatagtaaag gactattgga attttaattt
     3541 ttttaggtag actttgaata gcagtataca aatcgctata gtcatctttt tcatcaattt
     3601 ttttgttttt gaagacatct tcaaatgata gagattttaa tcgtttgcgt cttaatgaat
     3661 tacattcatt tatgactatt ctaatcagcc atgttttaaa gtattgttct tccttaagag
     3721 aatccaactt ttcatatgct tttaaaatag cattgttgac ggcatcttca cagtcttggt
     3781 cgtttcctag aatagactta gatactcgat acaaagtctg ttctgattca agtatattgt
     3841 ttgtaaatgt agttttatcc aactaagttc cttcccttct atgcaaatcg tagcgctact
     3901 tttttgtctt tcacttatta gataaaattt tactatagat ggttcacttt ttttatgatt
     3961 atttgataaa tttaagtttg aaagttttgc ctattctata caaatattct ataatatatt
     4021 ttttctagta ttttcccctc atatataaag ccatgtagat atattaaact ttagaagcca
     4081 tttatatatt tagttttata gtaagtcttt atattgagta attagaaaat agtaagtatt
     4141 taatgttgag tagttagaat aacaatgctt ttggattatt tacttcatgt acagatttaa
     4201 aataagttct ttaaatagca actttttgaa aaaacgcaaa aatattttat gttgtctgat
     4261 tatatttata gatgtgaaac aatattgtat agagtaaaag tatatagaag atgattacat
     4321 agagtttata cttgaatttt acaaatataa ttatcaaaat actgtcaaag agaaaaatag
     4381 ttttgatgaa cgtttttatc aaattgctac agagacaggg ctaagtgcta atactgtata
     4441 taaagtattc aataaaataa taaatagtgg aaaaactgaa tttacatcaa aggaattagc
     4501 tactatatgt ggtgtaagta ttagaactat ggacaggatt atacttagat tgtgtgattc
     4561 tggttattgt gaggtagtga gtgaacagct tatgagcaag tatggtagac ccagtagaat
     4621 attacgtttt aaaccttttc tgttgtttta aatagatata agtcaaaaat taaattttta
     4681 tgataacatt ttctttacaa ttttttagat atatgttaat atttagaaaa atgcatatgt
     4741 attcataaaa taaacttaaa acagctaaaa aatcattaaa aaggaaattg tatgcatgaa
     4801 atgagaaagt taatttataa cttaaataaa tctgggagga gataattatg ggaaaatatc
     4861 aggattcaaa aaaagttgta agaaattatt ttgaagcatt agaaaatgct actggggatg
     4921 aggttgaaaa tgtcttaaag caacatatga aatcagatta taactggaaa ggtgtgtatc
     4981 catttcgtga acaagaaggc actgaaaatg tagcagatgt attttggaag cctttaaaaa
     5041 aatcattgag taatatgcaa agacgacaag atattttcat tgcaggaaca aatgagattg
     5101 acaatagtga atgggtaatg agtatggggc attttatggg actttttgat aacgattggc
     5161 ttggcattaa acatactcgt aaaatgatta gtttaagata tgcagaattt aactgtgttc
     5221 aagatggtaa aattgctaaa actggattat ttgtagatat aattgggttt atgattcaag
     5281 caggagttaa tccattgcca ccacaaacag gttcatattt tgtatatcca gggccaattg
     5341 accataatgg attacttttt gaagatgcag atgaagttga aggagtaaaa actttagcat
     5401 tagtaaataa aatggtagat gatttatctg aattaaatga aagtggtgct atgggatgcc
     5461 caccagaaat acttgaaaaa tcttgggcta aagatatgat ttggtatggt ccaggtggaa
     5521 ttggtgcttc ttatactata cctagatatc aagagcaaca ccagctacca tttagaaata
     5581 atttaaaagg aaagactttc aatgggcatg tatgtagatt tgcagaaggt aattttgctt
     5641 gtttctttgg atggcctaat ctgactaatg taccatgtgg aggtttttta ggattaccag
     5701 gtggagaggt taaagcagat atgcaagttg ttgatgttta ttatcgtaag ggcgataaac
     5761 ttcaagaaaa ctgggtgtta attgatattc cttattggtt gaaacaacaa gggcttgata
     5821 ttcttgagag aactaaaagt atttttaatg cttagttatg catacgtatt ctaaaataaa
     5881 gggggatata aagtggcatc taccaacaaa aataatgcaa caagtaaaga agaagaaaaa
     5941 gaagtttcta caagtgggct tgaatcatgt acggttaaag aaaacaaagc taaaatgaat
     6001 caaactaatt ttagtaatat aaatgaaaat caaacaaatg agaataaaac gaacacatat
     6061 aaaagaaata tagataaagg aaatatagat aaagggaata tagataaaac aaacacaaat
     6121 aaatccgaca taaataaagt taacatagat acagtggata cagataaatt aaatacaaat
     6181 actcttacta aaaaaaataa aaaagttata tttaaggggg aagataatat gtcatctaca
     6241 aaaatttact atggagattc attagaagta acgcctgttg gagtaatgga ttacaatgat
     6301 ttttcaaaac agacaaaaag ggaacaggaa atacctggat ttgattctaa gtatagagat
     6361 tttgtagatt atattatgaa gattacacat aatatctggg aagaaaaagg tataggtgtt
     6421 atttatgata catatcacaa taatgttaca atgcattgtg gctcttcaaa tttagttggt
     6481 attaaagatg ttatttccaa tactcttcaa acattacatg cgtttcctga tagaagatta
     6541 attggtcaaa atgtaatatg gtctaacttt ggtgctgatg gttttttatc ttctcaccgt
     6601 gttttgtcta cagcaactaa cttaggtgat agtaattttg gaccagcaac aggtagaaaa
     6661 ataaacttta gaactgtaat tgattgtgcc acaactaaca atagaatcca cgaagaatgg
     6721 ttggttagag ataatttatg gattgttact caattaggat taaaccctca ggaagtagca
     6781 aagagtatgg caaaggcaag tgaatctaaa gtgcttagtt tacaatcaac ttatggtatc
     6841 tgtgaatcta tggatggtca atttatgcca actaagtatc aagcaaaaga tgattctgct
     6901 ggcgaaatga tgcttgaaat gacaagccgt atttataatt ataaatatat aaatgaagtt
     6961 aaaaaatact atcatgataa tgcagtagta cattttatat gtgataaaga tttaaatggt
     7021 tatgatgaga ttcaaggaat gattgtaagt ttacttgcat caattccaaa tggaagttat
     7081 gaagtggaaa gagtaacttg taatcaaaga gaaaaaaatg aaggttatga tgtatctgta
     7141 agatggagat tacgtggaat aaatgaaggt ataggatttt ttggacagcc ttctggaaag
     7201 catatagaag taatgggaat caatcattat catatactac aaggtaaagt aaaggaggag
     7261 tggataactt ttgatggtat ggatgtatta aaacaaatgt atatgggagt agaagaataa
     7321 agctgtttag agtataaata gttttgaaat atatagggaa gtattgcttt ataaaattta
     7381 agtggggaat gtatatgaaa aatagatgtt taaactttta gcaaaattat gactaaattt
     7441 aaaaggggga attataaaaa tatgaaaaca acggttgaaa tagaaaatga tatcatatta
     7501 ggaaaagact attcaaacct aaaaagagga attgcatttt tttcaattgc tttaatatac
     7561 tttttttatt gctacaattt tatggtgggt acttttatta aaccaacaat gatttatgct
     7621 ttagcagatg ggggatttgg tttttcatta aaacaaacag aagaaatatt tgcagttatg
     7681 tcttttggta caattccagg tacatttatt tttggggtga tttctacaaa aattgggaag
     7741 aagaggactt taattagcgt tgctttactg attggattga caacatttat accaatgtta
     7801 tctcctacaa atattatgtt atggaaaata gcacgtttgt gtacaggagt agtgttggga
     7861 ggcgtatttg gaacagctat gcctttagtt gcagatatgt ttccaagtaa atatcgtggt
     7921 aagttagctg ctatattaac tgctttattt tcattagcaa tgatttttgg tgggaaagta
     7981 tatggcgttt taggtgatgc aaattggcaa atattgatgt atactgcgat tataccacct
     8041 atagttggag ctatcttagc aattttcttt gtgccagatg atttggagta tacaaaggaa
     8101 ttagttaaaa agggaaaaga aactggtgaa aagattagct atataagtat gtataaggga
     8161 aaatacttat ggattggatt gggaacgatt cttttatcag gtgcaaattt tacagcatat
     8221 tcagcatttt caaataatgc aactacatac ctagtgacaa gaataggaat gtcagcagca
     8281 gtggctgggt ctatatatag tttacaagga attggtcaat tagtaggata tttattctgg
     8341 ggttcaattg cagataaatt tggaagaaaa atacctttta taggtatggc attagcagca
     8401 gtatttgttt ttatatatac aaaattaggt ggagataata caacaacatt ctatatgata
     8461 tcagtattac taggtgttgc tgttggatat tctggagcat ggggagcata ctacacagag
     8521 ttgttcccaa gtaaatatcg ttcgttgtca tctggtatgt catttaatgg aggaaggatt
     8581 atatctacgt ttgcaatacc tgctatagct ggtacagctt ctggtacttt aggtatgatg
     8641 actatctttt acatatcaat cgcagtcttt gtagcaggtg ctattgtatg gttattctta
     8701 ccggagacgt taaataataa aaaataaaat actaggaatt tattttgtta cttagaaagg
     8761 ggtggcttat gatttcatca attgatgtat gtattataat aggatatttg ctattaatgt
     8821 tagttattgg ttattattca ggaaaagata ataaaaatca agaagattat ttcttggcag
     8881 gtaggtcaat gccatggatt ccaattgctt tatcagttgc agctactatg attagtgcaa
     8941 atggctttat aggtggtcct ggatgggcat atgtagatgg aatgtatcca gtaatggtta
     9001 atattacagt acctttagca atattttttg cactgagcat taccacccca gttatctata
     9061 aattaaaaat aacctctata tatgaatata tgggacttcg tttaggaaat tattcaagag
     9121 gattaactat tattcaattt tttattaatt cattgattca agctagttct atggtatata
     9181 ttccagtgct tattattcaa atgattactg gctggtcact ttatgcttta gtcccaatag
     9241 ttgtacttgt atcaattata tatactctat taggtgggat taaggcagtt atatggactg
     9301 atagtattca aatgatagta gtaataagtg ctgtatttat agtaattatt gtagccttaa
     9361 aaggaatgaa tctaagtttc tttgatacat tacaaattgc acaacagagt ggaaaattaa
     9421 atacatttga tttcagtagg gatatttcag tgacaaatac tttttgggct actttaattg
     9481 gtggaactgt aatgtggata agatactttt gttttgacca atctcaagta caaagagttt
     9541 taacatctaa atctttaaaa tgtgcaaaaa attcttttgt agttagtgca tttgttatga
     9601 atttagttta ctactttatg ctattggtag gagtaatttt atttgttttt tatgggggaa
     9661 ggacatttga aacttcaaat gaaataatga ttacttttat tttaaatgaa cttccagtag
     9721 gagccattgg aattattatt gcaggtgtgt ttgcagcagc aatgtctagt atcgactcta
     9781 tattaaacag tatgacaact gtttttacga aggatattta tgagttttat ttcaaaaaag
     9841 acaacaaaga atcatcatta aaagttacaa tgattataac tgtagttata ggagttgtta
     9901 tgacaggttt tattattatg ggatttggag gaagcatcaa atcaattctt gaccttgttg
     9961 gtaactatat ctcatacttt gctggaccag ctacaggtgc atttgtacta gcaatgttta
    10021 catataaagc taatgataaa ggagtatcta ttggttttat tgtagggtta gttttaggat
    10081 tttttatttc taataaatat aatgtgagtt ggttgtggaa tccagcaata ggtgctacaa
    10141 taacattgat atttggatat atttttagtg tcattttaaa gaaaaatcat aatgcagatg
    10201 atattaaaaa atacactgca tttggtatga gaaatcacct tatttctcaa ggaatggata
    10261 aagtagatgg agtatctata gtgccatttt ctttaggtaa acaagaacta attgtattag
    10321 ctttttttat tatccaatat attatattat ttttgataca attttaagaa gaaatactag
    10381 atatttaagg agaaatacta aatgaatcaa aagaaagttc attataataa atcggctacc
    10441 tcaaaagatg ttgcaagatt ggcaggagta tctcaatcat ctgtttcaag agcatttggt
    10501 agtgcaaatg gaaagggcgt aaaacctgaa gtaagagaaa gaatttttcg tgtagcaaac
    10561 gaaataggat atgttcctaa tttggtagca cggggaatga ttagtggaaa aactaatgtt
    10621 ataggattga tagttggtga tagtctaggt ccattttaca atagaattat caatttattt
    10681 gtagaaaaaa ttcaagagat aggtaaacag tgtctcgttt ttaaagttcc tagacaacaa
    10741 agtatagata gtataatttc aaaagtaatt cagtttcaag tagaagctgt gattattaca
    10801 gcttcggcca tgaataaggt gatggctgag acttgtgaag aaaacaatat tcctgtgatt
    10861 ctttttaatc gttttatacc tggtataaaa ataagtacag tctatgtaga cccaattgaa
    10921 ggtgggggaa tggctgctga atatctgctt aagaaaggtc ataagaatat aggatatatt
    10981 caatttacga gagaaacaag tgaagaaatg gaaaagaaaa ttggatttta ttctaagtta
    11041 agacaaagtg ggattcataa ccttaaagaa gaatctgcaa actatgatta tgattctgga
    11101 tatgaagcag gtaagagaat gttagcatta tcaaatcctc caacagcaat tttttgcaca
    11161 agtgacttga tagctattgg tgtaatggat gctgcaaggt ttgagtacaa gttgagggtg
    11221 ccagaggatt tatcagtgat aggatatgat gatattcaaa tggcttcatg gaagagttat
    11281 aatttaacga cgattagaca gccactagat ttgttgattg aaaaaacaat taacatactt
    11341 aagtccttat taaatgaaga aaatccagag tcagttgttg aaatgttaaa acctgaattg
    11401 attgaaagag gttctacact ttaagtggta gatatttaat taagtggtag atacctaatt
    11461 aagttgtaga tatctgataa gaaattttta agttttcaat cgttctaaat tgtgagtata
    11521 aaaatctact aaatttagtt atgtaaaata taaattataa gtgtagaaac taggctacta
    11581 gcttttatac cacttcaaac attactggag gtagttaagt ttacatcagt ttagttttat
    11641 gtagatataa tattctgtaa atagacaaaa ttaaaatatg taagtgtctc aaaatgaaat
    11701 ttttagttta tgaggcactt ttttgtataa aatcaaatgt atttttataa ctttaacaat
    11761 aaaaagaggc ttatctctat tttgagacag cctcaaattt ttaaaactat attagtttac
    11821 agcttctttt cctatcaaat cttttaactc ttcatgagtc atagtttctt tttcaaataa
    11881 gaatttagaa acagaatgta aatcttcaag attatccttt aacatctcta aagtctcttt
    11941 ataacaaatt tcaactatac gatttgcttc cttttgaacc ttatcacata agaaagtctt
    12001 atcatttcca tcaatagtca taaatcctaa gttactcata ccatattcac aaaccatttg
    12061 gttagctatt tcagtgactt tctttaagtc gtcctttgca ccagtagatt tatgattaaa
    12121 tattaattct tctgaagcct ttccagcaag taatattttt atttttccaa tcaactcatc
    12181 cttagtataa atatatctat cttcatcagg taattgaaga acataaccta atgcttgtcc
    12241 tctaggaact atagatattt tttgtatagg acaaattcct actatatcac ttacaagagc
    12301 atgtccagct tcatgatatg ctactatttt tttctctttt tcaaccaatg cagagttttt
    12361 agattctagc cctgcaataa ctctttcaag tgccttgtca aaatgttctg atgtaataca
    12421 ctcactgtca tctctaactg caaatatagc tgcttcattt gctatatttg aaagatgagc
    12481 cccattgaaa ccatgagttt ttttagctaa aagttctaga tttacagatt tgtctatagg
    12541 tttgtcatct gtatgtacct ttagaatttc aaatctagtg tgatagtttg gtgcacctat
    12601 atgaatgtgt ctgtcaaatc ttcctggtct aagtaaagct tcatctaata agtcaagtct
    12661 attggtagca cctattatta atacattgga atctttatta aatccatcca tttcaactaa
    12721 aagttggttt agtgtttggt ctttttcgtt gttactttca agatgtctct ttgctcctac
    12781 agcatctatt tcgtctataa atattatact tggagcttct tttctagctt tttcaaatag
    12841 agttctaact ctttttgctc ccacacctac atatttttca acgaactctg aaccagtaac
    12901 attgaaaaat gatgagtttg tttcaccagc tacagcagat gcaagtaggg ttttacctgt
    12961 tcctggagga ccataaaata atactccttt aggtattttt gcacccattt tttgatattt
    13021 ttgtggtgac ttcataaaat cgactatttc aaatagttct tcttttactt catctaatcc
    13081 agcaacatct ctaaatgtag tctttggttt tgtagaaagt gaatcatctg tttgattatc
    13141 tctttccatt tttgtctgtg caaagacagg agctggattg ttgattttct taaaaaagtt
    13201 gtttagcatt ttcatattca cacctcaggt aattaattat tgttaatcaa ttttatattt
    13261 tccatattta ctatttttta ttatttattt ttcatggaaa aaatatacat gttatctaaa
    13321 taaaaataaa tttgtaagat gtatgaaaaa atgaatttat gtatatagag atttctactt
    13381 atgtattgaa taaagtatta caaattataa attatgtatt gattatatat tgagtaaagt
    13441 attataaagc atgtattgat taagtattga ataaaatatt acaaatttag ttgaaatgaa
    13501 aatgataaaa aatcttgtac tatattttac aaatcatata aatagagaaa ttgttgtagc
    13561 acaaagtagt aggtagtata ttagaatata atataggatt tgttgtgtag tatagtagca
    13621 tattagaata taatatagga tttgttatgt agtatagtag tatattagaa tacaatatag
    13681 aatttgttgg gtagtatagt gttatattag aatacaatat aggatttgtt atgtagaata
    13741 tatagagtca tgtagaatat aaatatataa aaggattttg ggtataaatt taaaaattaa
    13801 tagcaaaatg agtagtatag acatataatt agtagtagga agtaattaaa tttttcctaa
    13861 acaaaaaaaa tagttgcaaa taatttgatt aagtgatata gtagataagg taagaataaa
    13921 acaaagaaga agtccgcttc tcaccttacg ccggaggtta gtaaggtaaa tataagttaa
    13981 agcttaattt taatttaagt ttgtttaaat ttggtaactt atattgcgga tgattacgtc
    14041 atccgctttt tattttataa aaattttgga ggtgtcctac aattagcaaa gaattagcaa
    14101 tcaatgaaca aataaaagat aaggaaataa gagtcctttc accaacaggt gaacaacttg
    14161 gagtaatgcc tactaaagaa gctcaagcaa tggctaatag caaaaactta gatttggttc
    14221 aaatctcgtc gaatgcaaat ccaccagtat gtaagataat ggattatgga aagtttagat
    14281 atgagcaagc gagaaaagag aaagaagcta agaaaaaaca aaaaactata gttgtaaaag
    14341 aagtaagact tagaccaggt attgaacaaa atgatttaaa tacgaaagct aataatgcta
    14401 taaagttcct taaaaaaggg gataaagtca aagttgaact tagatttaga ggaagagaat
    14461 taggacataa agacataggt aaagaagtta tgcttaagtt tttagatata ataaaagagt
    14521 ttggagaacc aacaaaagcc cctgcatttg agggtaataa tatggttgta attatagatc
    14581 caaaaaaata gatgattaac tgagaggagg aatttgtcat gcctaaaatg aaaactcata
    14641 gaggtgcagc aaagagatta aagaaaacag gaactggaaa gttaaagaga gctaaagctt
    14701 ttaaaaaaca tatattaact aaaaaatctg caaaaactaa aatgaactta agaaaatcaa
    14761 ctttagtaag tgatggagat gctaagagaa tagcacaatt attaccatac taagatacag
    14821 attgtaaata ataactatag aagagggata taaaaggagg tcataacgat ggcaagagtt
    14881 aaaaaagcta tgaacgctcg taaaaagcat aagaaaatat taaaacttgc aaaaggattc
    14941 agaggatcta gaagcaaatt atatagacca gcaaatacat tcgtaatgaa agcattaaaa
    15001 aatgcttata taggaagaaa gttaaagaag agagacttca gaaaactttg gatacaaaga
    15061 ataaatgcag ctgctagaat gaatggaata tcttattcaa gattaatgaa tggattaaaa
    15121 ttatctggta ttgaagttaa cagaaaaatg ttatctgaaa tggctataca agacccagaa
    15181 ggatttgcaa aattagcaga agttgctaaa gcaaaattag cttagtattg aatcatgaga
    15241 tgtaaagtct ttgagttata taaataattc aaggactttt ttattttttg aaaaatactt
    15301 attagtgtca tgtacaacca attttataat gataaataaa ataagcaata caatagaatt
    15361 ttatgagatt tattataaga attgttacaa ttatttatga tagctataaa aagtcatagt
    15421 aaaaatgata ttgatgtatg ttgatatatg tataaagctt tcaatcaatc ttgaattaat
    15481 attatcaaca tgataatatt atcttattaa taatataaat aagggggaga taatatgaat
    15541 gaaaaactaa tggattgttt tgtaaaccca attaaatgca agttattgat tgaaattttt
    15601 tcaaataatc gaactacagc taaacaatta ggagaaaaat ttcaagatat atcaaaggca
    15661 acactttatc gttaccttaa taaaatgttg aaagatgata ttataaaagt agttgaagaa
    15721 aataaaataa ggggaactgt tgaaaaagta tatgctatga agttagatat agctgatgat
    15781 gtgaacaaaa ttatagatga gaactctgga gaagaatatg ctcaactgtt tactcaatat
    15841 atgatgggat ttttaagaga attttatgaa tacgctgaaa gaaaggaaaa ggatatccta
    15901 aaagatggtt caggattttc tgtctgtcca gtatatgcta gtattgatga gatagttgaa
    15961 gtgagtaaaa aaattgctag tatactagaa cctctaagaa ataactcgca cgaagaaggc
    16021 agaagaatgc attctatagg agtgataatc actccaccta aagaggatga agggaaataa
    16081 atctgattta catgaggtag agccaattta cacggaaaat cgttttatga tttacatatg
    16141 tatccagagc aaagtatctc tgcttggatt gtacttcatt gtatcatttc atctatctaa
    16201 tgacttggag tggtacaatg aagtttttta atttttcata tcaatgccta aagaaatgaa
    16261 ctttagacca catatgcaat taggttacat tatacaatta gaccagatat acaaaataaa
    16321 aatcagtatt tttatagcag ataaattgac tgttattctt cttaaaaatc atctattagt
    16381 tattgttagc atattgaaag aaattatagg aatctattga ataaatgaat attgcccata
    16441 atcatataaa ctgctatagt ttaaaataaa gcaggacgtt aaattttata gtaatctaaa
    16501 aatttaagag ggggatttta tgaaaataaa atttgttatt atgccattgg tgatattttt
    16561 aatggtatta tttgtggggt gtcaaagtac aaaagataca gaagttaaag caaaatatac
    16621 agaaattaaa atattaggta caggtgattt gcattcaatt ttgacagact ctatggtttc
    16681 atatgtaaat gaggaaaggg aaaagaataa aaatctgctt atggtagatg cgggagattt
    16741 ctatggtaca caaagtagag aaatgtggga atggtcttct ggaaaaaagt taattaatat
    16801 taaaagaaat ggtagagcag agtatgatga cataattaag agtagtaaag atgaagtacc
    16861 tatagttaaa gatatggcaa agttgaaata tgatgctgta gttttgggag ataatgaatt
    16921 tgtttcaaat gataagcaaa gtcttgataa actagtttct gattttaaaa ataataatat
    16981 gccattggta tcagcaaata tatatgaaca atctggagaa aattatgtac aaccatatgt
    17041 aatgaaaaat attaagacag atgagggcaa tgtaaaagtt ggaatactag gtcttactat
    17101 aaaagaagta ggggaaaccc ttggtcttga ggattttgaa aaggataaaa aagctagaga
    17161 gcttggagaa caagctgatt acaaaggaaa attatatgca aatgatttag tagaagatgc
    17221 aaagaaatgg ataaaagtta tggaaaaaga aagtccagac ataatagttg cagttgtaca
    17281 ctcaggggaa gaacctaaaa cagatagaaa tccaggaaat agaataaaag agttagcaac
    17341 tacagtggat ggaatagatg caattgtagc tggtcatact catgaaaaaa tagatgaaca
    17401 caaatataaa aataaatctg gagatgaagt aattgttaca caaccaggtt ggcatggaga
    17461 tagagtatca gagattaatt tcaaattaaa taaagagaat ggaaagtggg acataaagga
    17521 aaagtctagt aaattaaaaa taattgataa agaagtaagt atagttgcta ctgcagattt
    17581 acattcacat ttctctgata aattaacagt tgaccttgtt aatgaacgta gtaacccaat
    17641 tgaacctgtt gtagtagatg caggcgactt cttagaccct caaacagatg aaatgactca
    17701 atggtataaa gagtggaaaa gtataagaga taataatagt gataaaacga ttagtagatg
    17761 cccaatggtc atggatatga atcagggaat gtatgatgca gtagtacttg gaaatcatga
    17821 atttgtatcc gaaaaagatg aattttggtc agatgaacgc cttttagatg ctgttataga
    17881 ggattttgaa caggtggcaa tttctgtgtt atcggcaaat atatataggc aatctggtaa
    17941 aaattatgtt aaaccatata ttataaaaga tgtggagacg agtgaaggta atgtaaaagt
    18001 aggaatattg ggacttacta taaaagaagt aggtaaaggt cttaaaaatg taaacttaca
    18061 agagcaattt caatataagg ataaattgta tgcaaatgat ttagtggaag atgcaaagaa
    18121 atgggtaaaa gttatgaaaa agaaaaaacc agatataata gttgcagttg tacattcagg
    18181 agaagaacca aaaaatccaa aacatccagg aaatagaata aaagaactag caactacagt
    18241 agatggaata gatgcaattg ttgctagtca tactcatgaa aaaatagatg agcatgaata
    18301 taaaaataag tctggagaaa aagttatagt gacacaacca ggtgagcatg gtaaatatta
    18361 ttctaaaatt acctttaaag taaataaaga aaagggttcg tggattatta atgataaatt
    18421 cagtaaaaca attgaggttg aataacttta taaaatttat agataaagta aattatctga
    18481 tattgacatg atatataaga taaagtttct aatattagta taatgcataa tgtgaaatat
    18541 tttaataata agagaataaa caagacaaat aaaaatattt taacatgtaa gatatagtat
    18601 gaactattat actaatgctt actttataat ttgaacatgt tagaataagt cttatttgaa
    18661 aattttagtg tattagagta agtattattt taccagtaaa aaatattgag aactatatgt
    18721 agatttgctt aaaaaggaat ttacatatag ttcttttcgt ataataaata gtacaatctt
    18781 atatggtaaa gataaagtgt gatattaaat tttattatca tccaaaatct aaggaggagt
    18841 ctcttatgaa aataaaattt attatagtag catcaataat atttttaata gtattacttg
    18901 tggggtgtca aagtactaaa gacacagaaa tcaatgtact cgccacaagt gatttacatt
    18961 caattattcc agataattta atttcctatg tagaagagga gagaaaatat gatgagaatc
    19021 tacttatggt agatgcagga gatttttttg acatgcaaag tggtgagatg aataagtggt
    19081 ttactggtca aaaattagta agatttaaag atgggatacc agagtacaaa aaaatagctg
    19141 aaccacgtga aggagaagtt ccattggcta aaaaaatggc aaagctgaag tatgatgcag
    19201 ttacatttgg gaatcatgaa tttgtatcta atgacaagca gagccttgat aaattggttt
    19261 ctgattttaa aaataacaat ataccattag tatcagcaaa cgtatatgaa caatctggag
    19321 aaaactacgt aaagccatat gtaatgaaaa atataaatac tgacaaggga actgtaaagg
    19381 ttggtatact tggtctgact ataaaagaag taggggaacg ttcaaggttt aaaagttttg
    19441 aacaagataa aaaggctaga gaacttgggg aacaacctca atacaaaggg aaattatatg
    19501 caaatgattt agtagaagat gcaaataagt gggtaaaggt tatggaaaaa aaagaaaagc
    19561 cagatataat agttgccatt gtacactcag gtgaagagcc aaaaaatcct aaaaatccag
    19621 gaaatagaat aaaagaacta gcaacaactg tagagggaat agatgctatt gtagcaggtc
    19681 atacacatga aaaaatagaa cagcatacat ataaaaataa ttctggtgaa gaagtaatag
    19741 taacacagcc tggagctcat ggtaatagta tatcaaagat taattttaag ttggataaga
    19801 agaatgataa gtggtttata aaagacaaat atagtgaatt aaagattttt ggaaaggaag
    19861 taaatataat tacaacttct agtctgaatc caaaattttc agatgaaatg gcagttaatt
    19921 tgtttaatga aagagataga gatgttcaac ctatatttat agatactgga gattttttaa
    19981 atactaatac aaaagaaatg actaagtggg ctaaagagtg gcaatacaat gaaaataaag
    20041 gcatctataa aaaaataaat gaatggccaa ttgtatatct tggttatgat gctgtagtac
    20101 ttggtagcca tgaatttaca gaggataaag agacttttga ggaaaaaaaa tctacattgg
    20161 attatattat agaaaacttt gaagaaatga agataccagt attatcagct aatatatatg
    20221 atgaatctgg agaaaattat gtaaaacctt atataattca taatgtagaa actagggaag
    20281 gaaatataaa ggttggagta ttaggtctta ctactactga taaggatgaa gaagacttaa
    20341 gtagctcaag cttaagcaaa gactcaaaga cttcgaaaat tcctgaagaa acaggaaagt
    20401 tatatactaa taatctagta aaagatgcaa gcgaatgggt aaaagttatg caaaaggaaa
    20461 gtcctgatgt gattgttgca gttgtacatt cagataataa tagtactcta aaaaatccaa
    20521 gtagtgaagt caaaaaactt gcaatgtcag tagatggaat agatgctatt gttgtaggtc
    20581 atacgaaaaa taaggtagaa gaacatattt acaaaaataa gtctggggat gaggttatag
    20641 taacacaatc tggagaagat tgttattcaa aaataagtct tgaactaaga aaagaaaatg
    20701 gcaagtggaa tatcataaac aaatatagta aagcaataaa aatgaagtga atttattgat
    20761 atataaacca ttattaacac tgatttttat aatataataa atactgattc tataatataa
    20821 ttaacactac tttttaaata taatcaatac cgattctata atattaacac tattttttat
    20881 gctatataac aattattgaa aatgatataa atataatatc tcaaataata tgaatataac
    20941 atctgaatag agggtgtttt atttgtaaaa aataagttta cagtttgagc gtataaactt
    21001 atggtaaagg agaataatta tgagttataa gaagattgca attataacgg gtgctaatag
    21061 tggttttggt aaagagtttc taaagttatt aataaatgaa gaagaaataa cagaaatatg
    21121 ggcagttgca agaaacaagg cgagattaaa tcaattagta gatgaatttg gaagtaaggt
    21181 aaaaattttt tcaaaagatt tatcaaaaat agaagaagta aaagaaattg gtacattttt
    21241 aagtaaagaa aatgtatgta taaaatacct tataaacaat gctggttttg caaaattctg
    21301 ttcatacaat gatttaagta tagatgaatc tattaatatg attgatttaa atattagtgc
    21361 tgttgtagca ttgggactta tatgtattcc atatatgcaa aagggaagcc atatcatgaa
    21421 tatttcttca caagcatcat tccagccatt gccatatcaa aatatttata gttcaactaa
    21481 agcgtttata agaaattata caagagcatt aaatgttgaa cttaagagta aagggataaa
    21541 tgcaattgct gtatgtccag gttggatgag tacaaatcta tttaagagag gtatagttgt
    21601 agctgaaaaa gggacaaaaa atttcccagg catagtgtct ccagacattg ttgccaaaaa
    21661 agcattgaag gatgcaaaga aaaataagga tatttctgtg tatggtataa atacaaaatc
    21721 cagtcattta ttagcaaaac tattgccaca aaaaatgatg atgaaggttt ggttaatgca
    21781 acaacatatt aaggaataag agtttcggta attaagtatc agttggagat tcaatctgtt
    21841 atatattatg agaagttttg ttgagcaaat aataattgtg acaaaacggc ttatctagtg
    21901 ccgataagcc gtctataatg tatataaaat atatttttga ttttacttta tttagatatt
    21961 gaagtattaa aatatgtagg acttgaaatt ttataaagat aaatactatg atattttgta
    22021 aaaactgaga tatgttgata ttacatagtt taactatact gttaaattga agttttctta
    22081 ttttgcatta tgcttattac ttaatgattt agactataat ttccatacca tcatatgcaa
    22141 aataaatgtt atcaagtttc ttttctaatt cactgtaata accatatgat tttccccata
    22201 tttcgtcaat atgtgtaatg ataatctttt taattctata atagttttta atttcaacaa
    22261 tctcatctaa agtaaatatt tcatctttaa atggtgtgtc tttaagtttt gtaccatcat
    22321 ttaatatacc atcatcagaa actagactta ttattaaaac atcagcatca aagtacatat
    22381 cactatgagt aaatggcttg ggattacagc aggcatatat gacttttttt tcattctctt
    22441 tgataacata gaaggttata ttcctgtctg ggttattgtt aatcaaatca atatcaaaat
    22501 tatttatctt tacatgcgaa gtttcattaa tagaaatgca atttataaca ttaccataat
    22561 atttaagaca atcgagattc gttcggttta tatcttcaat tacttcagga agcgcataaa
    22621 agccaattgg attattttct cctgtgataa agtcacatcc tattttttcg acaattctaa
    22681 tacccttaac atggtctggg tcatggtgag aaattgaaat atgttttact tccgatattt
    22741 tttgtctgtt acaagctact gcaatatctt caggtgtgtc tatcagcatt tttatatcat
    22801 caatatataa acttggccct aatcgttcat atcttccgcc tttttgtctg gcttcttcac
    22861 atattttgca tttgcaaaat gaacttggaa taattgacat accgccacta ccaacaattt
    22921 ttaatttcaa agttattaca ccaccttctt aaaatattag attatataaa taatctacaa
    22981 tcacaactga ttaacaaaat tatgagttaa taaattatat cacatgtaaa tatgaaagaa
    23041 tagtatgaaa tttttataaa catatattaa atgtttctca atgaaattga ctttgtatat
    23101 gaactgaatg acttattcaa tatggataag acatttttct tgtaataaga tatgattgtc
    23161 ctataaggtt tatgtaattt tgatataatt tgatataata tattgattaa caacatacat
    23221 gttattggtg agcatatttc tatagaatgg aatatataat tttttatatt tatcattgta
    23281 ttattgtcta aagaaagtta aaaagagtag agcacaaagg aattatttgt actttactct
    23341 tttattgttt tgttaaaaaa actaatttat attagtgatt aaaatatatt taactagagt
    23401 ataaggatag tatataatct tataattgat ttatctgaca aattaagata atatcctaat
    23461 taaattgtag atatttatac ataacactaa aagtaatttg tttaacaaat taagataata
    23521 tcctaatcaa attgtaggta tttatacata acactaaaag taatttgtct aacaaattaa
    23581 aatattatcc aattaatata aaaattactt ctttttaact gggaagcata cctctgttac
    23641 ccaattatca ggattactat cgttgccagg gcttacatga taaatattaa acataggacc
    23701 atccacatca tagttattat ctgatatcca attaccaata gcctcacaag cgtctgcaac
    23761 ttgattgaaa tttccattaa caattgcagt tgcagcagtc acacttggaa cagtcttaaa
    23821 tttaacatgt tcagtatctt tatactttcc agatacagca acttgtactt caacatctac
    23881 ataatcttct ttatatccag tatcataaaa aactgcttta gaatactttg ggggttcaat
    23941 ttgaacattc tggtcttttg tctctaaaaa tacttgatgc cataacattc cttcgtcttg
    24001 gtaagttggt ataacccttc taagtgtcat catatatttt ggtgcaaaat tctttatagt
    24061 tacatcataa tttttcataa tatcatttcc tccaattctt ttaatagtgg tttctatttt
    24121 taatagtttt ttctgtgtat cttctaattg ttcttttact tgagaatggt ggatatttag
    24181 atattttatg agactttctt tatcgttata ttctgtcaaa atttctttta tagaatacaa
    24241 gccaaagccc atatctttta gtgcatggat tctgtttgta gtagaaagtt ggtctgcact
    24301 atagtatcta tatccattag ttttattcgt atgagaagga gttaaaagtc ctatttcatc
    24361 ataatgacgt aacatacgaa tactaatttt acttagcttt gaaaaatcgc ctatcttaaa
    24421 catgtttttg tctcctttat aaaggtactt ttagcttaat attaatataa accatatcat
    24481 aatgttagag tcaactaaaa ttataattaa attatattga catatgatga aaaaaatatt
    24541 atactgaaca tgttcagaac cgaaaatgtt aattgttttg gaggtctatt atgaaaagta
    24601 atgataaaga tgctagagaa cgtataattg aagttacatt gaatctttta aatgaagtag
    24661 atgatattga ggagattaca gttagaaaaa ttgctgagcg tgcaaatgtt ggagttggtt
    24721 taataaatta tcattttaaa acaaaggata atttgttgag tactgccata ggagatgtga
    24781 tgtcaaatat aatagcagag ctatatgacg atagtgtata tactctaaga cctattgaag
    24841 atttaaaaaa tttattaaaa aaattgtgtg atactggatt acattatgaa aaagtgcttc
    24901 cttttgtatt gaatcaatgt ataaccaatg gagatatgca agcagaactt gatattgtcc
    24961 ctatgcttcg taaaattttt ggaaataaaa aagatgaaat gagtctaaga atcattgccc
    25021 tgcaaattat tttaccaata cagatttctg ctttatctac agaatcattt cagttataca
    25081 gtggtataaa tataaagaat aaatatgagc gagataaatt cattgatatt ttaatagaaa
    25141 atattattgg agaggatgtt gatgtaagat gaaaattata actattggtt caagtcttat
    25201 cactgtttta ctttttcttt caactatggt ttgtgggttc tggattaaga ataataaggt
    25261 aacagatgca agttctatta agttccatat gaatagtgct atttttacag ggatattttt
    25321 attgatttcc acaatccttt taattatata tataaaaaaa taataatatt attaataaat
    25381 aaagtatcag aaattataaa gacaagagtc ttaaaaattt ctgatacttt accatataat
    25441 tttattaaac attaattgtg tgtgaaaaaa tatcacttat ttcaatctaa tactaaatct
    25501 taagagtgag tataaagtat tagaaattaa gaagcatttt ttagttcaag tggattatct
    25561 ataccaaaat aatcatataa agtagagctt atttcctcta aatttccatt ttggaaaggt
    25621 aattgtaaat ttaccttttc taccacatct ttaaatccag catcagtatt ttgatttaaa
    25681 aaatccatat atacatcaac agcttttctg taatcttctt gtgataattg ccatatctga
    25741 agtgatacat cagatgcaag accataactc aagtaataaa aaggaacttg gaagttatga
    25801 gatacaagta tccaaaaagg agcatttttt tctctaagta tattattgga aactccatat
    25861 tcttcctcta aatcaaaaaa caatttattg atatcattta gactcatata tggattcttg
    25921 tatataattt cttgaaattc atcataaaga caagcatcaa taatagtatt taaaacaatc
    25981 gataagtgtt ctttttttat agcttcagat tgtttaccaa aaaaatcatc aaaatattta
    26041 taaaatagaa tttctaaaga tgttgaatga acttcacata catctatact tggttgcatc
    26101 ttattattta agttaatact gttgtagtaa ttataaaaat gaccaaactc atgagcaaaa
    26161 ctagtaacac ctaaaaaaga attgtcccat gtattaaaca agaaaggtgc tttatattta
    26221 tttatataag tagtatatcc tccaggtgat ttgttttttc cagaagaata atcgtacaag
    26281 tcatattttt tcatatagtc gaagctctct tttagttttg gagatatatc ttcaagtact
    26341 ttatcaaact tcctaaatga gcgattttta tatactttaa tataaataga agaatcagat
    26401 ggtttagatg aaatctctct atataatgga actatgtaat cttttacatc ttgtctaaat
    26461 tttttagctt cttcttgaga atagtctttg tttaggttca tataggcata atctatataa
    26521 ttcttaaatc cttgcttact tgctatttca gttcttgtct gtataagttc taagaatatg
    26581 ttaccaaata taggattgta tttttttaag taatctgaat aaattttcac atattcttca
    26641 gggctaagat ttggtcttga caaggcttct tcaaagtcta cctctatacc atctattgat
    26701 actgtagatt tagctaataa atcttcatat tttacaacta ggtcttgctc ttttttaagc
    26761 aaaccttcaa cttctttaga attaagtttt ccaatgttct ttagataatt aaatgtatcc
    26821 tttccaagtt ctttttctaa ttctttagag aatttagaag ttacaaatct atcttgaaag
    26881 tctttgtatg acatgtcaac atctactgat ttactcataa gatacttata ttccttagag
    26941 taaaattcgt ctgatgaatc tatgttattt ctaatttttg ctatagtaag tgtactgtaa
    27001 aaatcctgat aaattttatc aacttcatta aataaattta attgttcctt agctgtttta
    27061 gctgttaaaa gtttgtcgtt acacttgtta atgttttcgc aaattgactg tatattagga
    27121 cgcttatatt ccattttttc aaaaggaata gttcctctaa cagaatcttt ttttgtatca
    27181 ttagtataat ttcttatgta tgatgcaaat ataataaaaa ctgcaattaa aattagaaaa
    27241 acaaatattt tcttcttgga tttaaccata aaaatcctcc aatcatggat atagttatta
    27301 attattttac tatattaaat ataaaaaatg catgttaaga aaa
//
LOCUS       DAMJVG010000052        26583 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.052, whole genome shotgun sequence.
ACCESSION   DAMJVG010000052 DAMJVG010000000
VERSION     DAMJVG010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 26583)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26583)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26583
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.052"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(130..324)
                     /locus_tag="PC512_002398"
     CDS             complement(130..324)
                     /locus_tag="PC512_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442136.1"
                     /translation="MFQVINFLCLFCVGFLVLDVMIYFCKDAMDIFEGTTNVNKVKSI
                     NVWADRVRANSYSYENKIAK"
     gene            complement(633..2162)
                     /gene="lysS"
                     /locus_tag="PC512_002399"
     CDS             complement(633..2162)
                     /gene="lysS"
                     /locus_tag="PC512_002399"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HDF2442137.1"
                     /translation="MKNNQQSNEEAQIQEDLSEVLQVRRDKLKKLQESGRDPFKESRY
                     DRTHYSMDIKDNFDSLEGKTTKIAGRIMSKRIQGKAGFIDIQDQEGRIQSYVRLDAIG
                     EEEYSVFSTYDIGDIVGIEGEIFKTKKGEISVKAKSVVLLCKSLQVLPEKYHGLKDQE
                     LRYRQRYVDLIVNPEVKNAFLIRTKALKALRAYLDDRGFLEVETPILNTIAGGANARP
                     FITNHNTLHIPMYLRIANELYLKRLIVGGFDKVYEMGRMFRNEGMDLKHNPEYTAIEL
                     YQAYADYTDMMEITENVIAHMAEVATGSMIVNYQGTEINFTPPWKRMSMEDCVKEYSG
                     VDFSTINTDEEALEVAREKGIEIKPGMRRGEVINAFFEEFGEDKLIQPTFITHHPVEV
                     SPLSKRNVEDPRRTDRFEAFANKWELANAFSELNDPIDQKGRFIDQLRKRELGDDEAF
                     EMDEDFLKALEVGLPPTGGLGIGIDRVIMLLTNSPSIRDVLLFPTMKPIDNNPNKEEE
                     N"
     gene            complement(2177..2656)
                     /gene="greA"
                     /locus_tag="PC512_002400"
     CDS             complement(2177..2656)
                     /gene="greA"
                     /locus_tag="PC512_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003514606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HDF2442138.1"
                     /translation="MEENKEFLLTQEGYDKLEEELENLKVVKRKEVAERIKVAISFGD
                     LSENAEYDEAKKEQAQVEERILKLENMVRKAVIIDESKIDLNVVTIGSIVKVKDLEFD
                     EEVEYTIVGSTEADPYDGKISNESPVGKALLGRAAKEVVEVQVPDGVAKFEILEIRR"
     gene            complement(2765..3733)
                     /gene="dusB"
                     /locus_tag="PC512_002401"
     CDS             complement(2765..3733)
                     /gene="dusB"
                     /locus_tag="PC512_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HDF2442139.1"
                     /translation="MKIGNLELKNKVFLSPMAGVTDLPFRLICKEQGCGLLYTEMING
                     KALCYDDENTKKMLKIEEEEHPVAVQIFGSEPEFMGRAAEIMNDYSNEILDINMGCPA
                     PKVVKNGDGSALMKNPKLAEEVLRAVVKNSKKPVTLKIRKGWDDNSVNAVEIAKIAED
                     CGISALAIHGRTREQFYTGKADWDIIAEIKKNLSIPVIGNGDVFTIEDSINMLDKTGC
                     DAIMIGRGAQGNPWIFKRINHYMNTGEILPEPTLNEKISTAIKHLKLAVEEHGEYVAV
                     REMRKHIAWYLKGLRNSAKLRDEINKIEDYQEVVSKLEYYMEDSLT"
     gene            complement(3870..4640)
                     /locus_tag="PC512_002402"
     CDS             complement(3870..4640)
                     /locus_tag="PC512_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III pantothenate kinase"
                     /protein_id="HDF2442140.1"
                     /translation="MLLVFDVGNTNMVLGIYKGDKLVNYWRIKTDREKTSDEYGILIS
                     NLFDYDNVNISDIDDVIISSVVPNVMHSLENFCIKYCKKQPLIVGPGIKTGLNIKYDN
                     PKQVGADRIVNAVAGIEKYGAPSILVDFGTATTFCAISEKGEYLGGTIAPGIKISSEA
                     LFQSASKLPRVELAKPGMTICKSTVSAMQSGIIYGYVGLVDKIISMMKKELNCDDVKV
                     IATGGLAKLIASETKSIDYVDGFLTLEGLRIIYEKNQE"
     gene            complement(4659..5249)
                     /locus_tag="PC512_002403"
     CDS             complement(4659..5249)
                     /locus_tag="PC512_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDF2442141.1"
                     /translation="MMNTSASVRKVNVRKMTIIGVLSAISIMLSMTPLGFIPVGPTKA
                     TIMHIPVIIGAIMEGPIVGAAIGFIFGISSLLNAITNPTVTSFVFINPLVSILPRVMI
                     GVLAYYVYQLIIKATNKVYISGLITGAIGSLLNTAGVLGMIYVLYADKYLHAMGKSGS
                     AGKVIMALAAANGVPEAIVGALVVAAVATVLKKSKK"
     gene            complement(5433..6401)
                     /locus_tag="PC512_002404"
     CDS             complement(5433..6401)
                     /locus_tag="PC512_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P1 family peptidase"
                     /protein_id="HDF2442142.1"
                     /translation="MYNNILDIEGLKVGQVEDRNGLTGCTVVICEEGATCGVDVRGSA
                     PGTRETDLLDPVNMVQKVHAVVLAGGSAYGLESTCGVSRYLEEKGIGFDVGVGKVPIV
                     VGAVLFDLGVGSFKCRPDLKMGYRACEVANTDILNQGNYGAGCGATVGKIRGQEYAMK
                     GGIGSYSIKLDNGLIVSALIAVNALGDVYENGKVIAGALNDKKTETIDTYKLMKQGES
                     KGGFSVDNTTIGIIATNAKLTKAGCKKISQMGHDGYAKSIFPIHTPHDGDTIFTISTG
                     EIEADITLVGSLAVEVVEKSIINAVKKADSVENIMAYKDIVKKREI"
     gene            complement(6394..7371)
                     /locus_tag="PC512_002405"
     CDS             complement(6394..7371)
                     /locus_tag="PC512_002405"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HDF2442143.1"
                     /translation="MRDKIIEIILNNKSEFISGEELSKQLGVSRAAIWKHMKALKEEG
                     YNIESVNKKGYRLAENPTDLLSPQNIYYKLDTEFIGKNIEHLDTIDSTNEHAKRIAIN
                     SVDGTVILSEHQDMGKGRLGRRWDSKPHEGIWMSIILKPDMEPFKAPFITLIAGASVT
                     KALNNLGANTLIKWPNDVILNGKKICGILTELSAEIERTNYVVLGIGINVKIMDFEQE
                     IADKATSLYKEGYMLSRVDIVRNVLTEFEKLYLDYTVNNSKEKTLKICRDYSAIIDKN
                     IYVLKGDNRELVKCLDINEEGNLLVQRSDGSIKEIISGEVSIRGEKGYV"
     gene            complement(7686..9656)
                     /gene="ftsH"
                     /locus_tag="PC512_002406"
     CDS             complement(7686..9656)
                     /gene="ftsH"
                     /locus_tag="PC512_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HDF2442144.1"
                     /translation="MNKLLKGAGFYLLVFIIIVGIVQFSGKPTEKIKDLKFSEVYREL
                     TDENISRLYFVNQTSVEGTIKDTNTKFKSYVPTEVMGNKLADEVLDQAKAGKLTFGGE
                     AKPSTPWFVEMLPTLLLIFFMVIIWFVFMNQSQGGGGKVMSFGKSKAKVHKDDEKTRV
                     TFKDVAGLDEEKEDLQEVVDFLKNPKKYIELGARIPKGMLMVGPPGTGKTYLSRAVAG
                     EAGVPFFSISGSDFVEMFVGVGASRVRDLFEQAKKSAPAIIFIDEIDAVGRKRGAGLG
                     GGHDEREQTLNQLLVEMDGFGVNQGIIIMAATNRPDILDPALLRPGRFDRQVVVGTPD
                     VKGREAIFKVHSRNKPLSDDVKMDVLARRTPGFTPADIENLMNEAAILTARKREKKIK
                     METIEEAITKVIAGVAKKSKVISEKERRLTAYHEGGHAVCAHVLEEVSPVHQVTIVPR
                     GRAGGFTMQLPVEDKFYATKNEMKENIVVLLGGRVAEELVLKDVSTGASNDLERVTAT
                     ARSMVTKYGMSSKLGPMSFDSDDEVFLGNSFSSKRNYSEEVAFEIDQETKRIVDGAYD
                     KTRSILQENMDRLEYVAQALLIYETLDAEQFVKAFNKELPLNEIENAVTEENSSKEVE
                     EQLTIKLEKDEEERNNVIDINKNLEDKSDKDK"
     gene            complement(9690..11078)
                     /gene="tilS"
                     /locus_tag="PC512_002407"
     CDS             complement(9690..11078)
                     /gene="tilS"
                     /locus_tag="PC512_002407"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HDF2442145.1"
                     /translation="MIFDKVLSTINKHNLIQKGDKIVLGLSGGPDSVCLLHVLNRLKK
                     DFNIEIYAAHLNHQIRGIEAQKDALYVSKLCEDMGIIFFVKSINVPKYCENEGLSLEE
                     GARKLRYEMFYEIKDKIKANKIAIGHNLNDQAETVMMRIMRGTGLKGLKGIDYIRDNC
                     IIRPILDVERNEIEEYCEAYNLNPRIDKTNLENIYTRNKIRLDLLPYMKDNFNSNVIE
                     SIVRMSNSLKSDNDYIEKEAEAKFREVSNIKEKGFVEINLDDFVCLHDAIKVRVLRNS
                     IKHILGDTNFVDQRHIEDIMSLEDNSKVNKMLTLPRNIFVYRKKDSIILTNEEIVNEE
                     IEFYYNVPSNGFIKIKELKQIIETQVMSIDRYKSMKLDNSSKGFDFNKVKGGIVIRSR
                     RQGDKIKLAMGSKKVKDLFIDLKIPREERCKIPIITDSEGIICVGDYKISENYKIDEN
                     TKEVLKINFNKL"
     gene            complement(11261..11689)
                     /locus_tag="PC512_002408"
     CDS             complement(11261..11689)
                     /locus_tag="PC512_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HDF2442146.1"
                     /translation="MEEKSLSVKISINTRQYDEKGNMDTIEMTAFGKIFYKNDGIYVI
                     YKEKEEDIEITNTIKILKNQVSIKKFGAINSTMLFKCGESSTTKYVTPQGTLLIDIDT
                     RELDINIQEGEHIKLKIDYNIKVQDLFLGRNKIDIYIGTK"
     gene            complement(11706..12512)
                     /locus_tag="PC512_002409"
     CDS             complement(11706..12512)
                     /locus_tag="PC512_002409"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HDF2442147.1"
                     /translation="MNNKPIGVFDSGLGGLTVLKEIMKILPNEDIIYFGDTARIPYGS
                     RSKETIIKYTFQAINFLKTKGVKAIVIACNTATARSLKEAQEKYDIPIIGVIEAGART
                     AVSSTKNKIVGIIGTEGTISSKAYNLEISKIDESIEIVNKACPLFVPIVEEGWANTEV
                     AKLTAKIYLQELKEKNIDSLVLGCTHYPILKRTIGEEVGEHIKLVNPAKETAKDLKKI
                     LEVQNIINNTEIHGTYQYYVSDIPEKFSDIAREFLKKKIDKIQKVEIQKY"
     gene            complement(12714..13199)
                     /locus_tag="PC512_002410"
     CDS             complement(12714..13199)
                     /locus_tag="PC512_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase"
                     /protein_id="HDF2442148.1"
                     /translation="MATLLALTFIFMPIKEVFAYEPTENIKKVNKQEKNIAKKEVINL
                     SDNDLMLLSKLVAGEARGESYEGQVAVAAVVINRVLDPRFPDTIEEVIYQKNAFSVVL
                     DGSIKMAPTDSARKAAQEALYGTDPTNKAVYFWNPEIATCKWINRLNPYMRIGNHVFA
                     K"
     gene            complement(13250..13909)
                     /gene="spoIIR"
                     /locus_tag="PC512_002411"
     CDS             complement(13250..13909)
                     /gene="spoIIR"
                     /locus_tag="PC512_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein R"
                     /protein_id="HDF2442149.1"
                     /translation="MRKIKIRLGLLILSLISVISIMTIVINGEVKKVDNISKDYKDKL
                     IRFHVIANSNTDEDQELKLKVRDEVIKYLQPKLQNSKSIKESEAIIKKEYSSLEEISK
                     NIILKNGYNYSVKVGIQYSNFPTKQYSNIVLPAGEYKALKIIIGKGEGKNWWCVMFPP
                     LCFVDESNGVIDKSTDDKLKEVLTDKEYKLIKQDTPKKTSRVKIKFKVLEVVKDLEKK
                     F"
     gene            complement(14054..14734)
                     /locus_tag="PC512_002412"
     CDS             complement(14054..14734)
                     /locus_tag="PC512_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2442150.1"
                     /translation="MENLTKLNLDNYKPLRDVVFENLREAILEGKLKPGQRLMEVQLA
                     EQLGVSRTPVREAIRKLELEGLVVMLPRKGAYVANMSLKDIMDVLEVRASLEGLAAYL
                     AAERISDEDIKKLKDISEEFKKSTLESDVDALLKLDVEFHECIFKATNNKKLIQLINS
                     LWEQVYRFRVTYMSAYDTSHNIVEEHKYLLDAIIKGDSELSKKYATEHIEKAEQFMID
                     KAMISKDL"
     gene            complement(14718..15608)
                     /locus_tag="PC512_002413"
     CDS             complement(14718..15608)
                     /locus_tag="PC512_002413"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HDF2442151.1"
                     /translation="MDFIRLKSRAKINLSIDVLGKRQDGYHFVEMIMQTIDLYDIVKI
                     KELDEDEIKVKSTSLDIPLDEDNIVYKAAKILKNKFYIKKGVEIFIEKNIPVAAGMAG
                     GSSNAAAVLVGLNHLWELRLSEDELKEIGLNLGADVPFCISGRPALAQGIGEKLTNIK
                     GLPCDTNILICKPDLFVSTKEVYQGLDLNNIKKRPNNKYLIECLKSEDIKAVSESMVN
                     ILENVTIGKHKEISDIKQVMMKNNALGSMMSGSGPTVFGLFKNKEDALIGKKELLKKY
                     KQVYVVNSSQKGVEICGEFN"
     gene            complement(15726..17276)
                     /locus_tag="PC512_002414"
     CDS             complement(15726..17276)
                     /locus_tag="PC512_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3794 domain-containing protein"
                     /protein_id="HDF2442152.1"
                     /translation="MELIKDVIKVDNRIDFGKFQTFIEAEAVVPDKKLDVYEIVKTEG
                     YISLKKIEMADGKILCRGSFNYNVIYIADDKNTISNVDGKVDINEVIEKDNVVQDMEY
                     MLFSEVEHMDCTIMNERKIKVGALMNIRGSLFEKQRLDIVKDVAQVEGIQKHRKEICF
                     QDIVGIEKAESSIRDTITINTEEIQSIISLNPCVKVKESRVTDNKVIIGGVLEINPLA
                     CTYEGELVELDRVGIEFTQFVEVPGVSDGMTEEVLLSMSDFNHIFKQNSESNTGLLEI
                     DCMACCKVKVTDEVTREVLQDAYSPQKIIKFDHKPIQLNKTLRRSEETFMVREGIRND
                     NDDIQIKDIVSVCPTMSIENSYIEGNKSIIQGIIKVEILFVPVEGLKLVYKISEEIPF
                     EHDIEMDNLTDTASVFNTACIDKVEVDLNRDQIDLIIKIKRFTEALDKKAENFIIKGE
                     DQGVYDLSKAPSIIVYICKEGDTFWNIAKKYNTTENEIAELNDIKLDEPIKPGKCLIL
                     EKKVVLVD"
     gene            complement(17370..17636)
                     /locus_tag="PC512_002415"
     CDS             complement(17370..17636)
                     /locus_tag="PC512_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HDF2442153.1"
                     /translation="MATVQTLDKIRVSLERHIGKKILLKANKGRKQIITKEGILEKVY
                     PSVFVIKLDDESNGYPRVSYSYSDLLTSNVKLQVFRDQDKLQIS"
     gene            complement(17784..18644)
                     /gene="yabG"
                     /locus_tag="PC512_002416"
     CDS             complement(17784..18644)
                     /gene="yabG"
                     /locus_tag="PC512_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation peptidase YabG"
                     /protein_id="HDF2442154.1"
                     /translation="MKVGDIVARKSHNKDIVFKIVSFGVDENNEKIAILKGIAFRVIA
                     DAYIDDLELVKAPDIKDILIDKNVENLLYKSVRKAKERQKRMTRAVPKLQLNPNTYGM
                     PGKVLQIDGDKEYLKICLDVYAQLGIPAVGVAVSEQNQYKEVRALLEKYNPDILVITG
                     HDAMTIKRGDIEDMSNYRNSSNFVKTVKEARKWQPNLDNLVIFAGACQSNYEKIISAG
                     ANYASSPGRIMIHALDPVFIVEKIACSRIDVVVPIDEVIEQTITGVKGIGGSETRGKF
                     RWAMPKTILH"
     gene            complement(18728..19666)
                     /locus_tag="PC512_002417"
     CDS             complement(18728..19666)
                     /locus_tag="PC512_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HDF2442155.1"
                     /translation="MKFIDLHCDTIAKLMENVETSELKSNKYSVDIDRLKKGDSLAQT
                     FALFVDTEEVKHPFDYCMSMANKFHEEMKKNSDEIALATNYEEIMKNQSEGKLTALLS
                     IEEGAVLEGKLENLKKFYDLGVRMMTISWNHVNELSFPHNKVEYREKGLTDFGREVVH
                     KMNELGMLVDVSHISDGGFYEIAKISSKPIIATHSNSRAMMNHSRNLTDDMIKVLANK
                     GGVTGINFFHLFLSDKSESKLEDMVRHIKHIVNVGGIDVVSLGSDFDGIDSKVEIEDI
                     SQMGKLYEPLKKEGFSEDDIEKIYYKNALRVIKEVL"
     gene            complement(19776..19937)
                     /locus_tag="PC512_002418"
     CDS             complement(19776..19937)
                     /locus_tag="PC512_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442156.1"
                     /translation="MFILRFADDDDNLSVKDFTSLTDLKKYISENNIDKTWHQIEEVK
                     KVIPNLKEE"
     gene            complement(19947..20444)
                     /locus_tag="PC512_002419"
     CDS             complement(19947..20444)
                     /locus_tag="PC512_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC-C domain-containing protein"
                     /protein_id="HDF2442157.1"
                     /translation="MSLYTEWRNLSDNHESQEAEVKFWEEYLKVEAGIYNEILNNKMD
                     VVEGKVSELAEKFGTTNEFFMGFIDGISESLKEDIVLEEVEADKEVSIKIDWEKLYNN
                     MVTVEAHWLYNLQGWEDILPADQRKEIIKAYKKSKTIVKEAKIGRNDSCPCGSGKKYK
                     KCCGK"
     gene            complement(20559..21269)
                     /locus_tag="PC512_002420"
     CDS             complement(20559..21269)
                     /locus_tag="PC512_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0489 family protein"
                     /protein_id="HDF2442158.1"
                     /translation="MENYEYSGFYIEKPVGNNVFSYDKRENKSIYVPKLINGTLNDVR
                     LGNEVVFNEVDENKEIKAKGLENMVEYVLGNKKIYVFDNHNHAFYFWAKSLLKGEFTK
                     GCKLVHVDQHKDTREPENYDVDVNNLKDVFRYTNEVLNVGSFIKPALKYNIFSELIII
                     DSLYGFDLEVESEFVLDIDLDIFSSDMDYIPFELKFYKIKNLIKKAKVITIATSPYFI
                     NQEYAIKVLKELFNYDII"
     gene            complement(21445..21975)
                     /locus_tag="PC512_002421"
     CDS             complement(21445..21975)
                     /locus_tag="PC512_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442159.1"
                     /translation="MDIRALPIRITKEEAIEIAKSGKNSLFSKLILKNKYAHEVRLHY
                     IEFKIITLKIHKTKSIFKNRRYSNDINELKILVNGSTGSGSIVQDFPTYEVVKNVDCN
                     IVQYSDKDERRVKAKANKMAMRLTHRFMGGIPEIEIVKIESIFRPYWVVFFGKVELNR
                     RVSYLPIEADGFVIGM"
     gene            complement(21992..22222)
                     /locus_tag="PC512_002422"
     CDS             complement(21992..22222)
                     /locus_tag="PC512_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442160.1"
                     /translation="MSKLVSKVKKDLEIKWLGIDGFLVLLYFLITGFIFYGILTRNDI
                     IVGKIIPYGVMSVVIVIFFDYIYRVLKMTRKK"
     gene            complement(22237..23631)
                     /locus_tag="PC512_002423"
     CDS             complement(22237..23631)
                     /locus_tag="PC512_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HDF2442161.1"
                     /translation="MLTFWENGIIVIFAFILLGIGYYFSRNVKDMESYYLGNRSLPWS
                     LIVGTLVASWYGGVGTVGSVEYAAIYGISAWAVWSIAAHIGRMPLALWVGPRIHIRTN
                     ITVPDLLESFYGKHVAIIGAILMFIYCAQLGEITAMGTIGNVAWKIDKELIGLIMVGV
                     VVVLTVLGGLMGVAITDMVLFFCMVFGLTMVMPGQFEQIGGFQGLTEALKDAPQLMHP
                     TKGMSAMKALMLIVYSFGAYSDPTFYQRFSAADSPKVGRRALLTCFSLWICFDMVLTM
                     TGLIVRATYPEMAPAAGYITLVLDTLPQGIRVIFIIGILGSIISTLDSYYLAAGATLA
                     NDIYGRITKKELSQKQLVKFTRIGVCLAAVMGLSVAFRFENVYDACIFVGSIWMGSAF
                     VPIVGGLLGNGRRTSMGGILGMIVGGVTFGYFKIFPVQSFELEPLVIAIPFSFIAWMI
                     GNRIGENLNTQNNL"
     gene            complement(23757..25010)
                     /locus_tag="PC512_002424"
     CDS             complement(23757..25010)
                     /locus_tag="PC512_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2442162.1"
                     /translation="MESKNNVKRFLIIFILAFGTTAMYSLPYMKSSFYDPMQQALALS
                     HTQIGNLLSLYGLVGMVSYFIGGWFADRFSVRKLITFSLIASGILGFYFSTFPSYSMI
                     LLIFVLWGFTTILTFFSASVKVVRMQGSESEQGRIFGFYEGLSGVSGTLISFIGLYFF
                     GKFAEITVGFKYVVWLYSAASIICGILLFFLVEEKKDSGASDEGLSIKSLLKVVTMPK
                     AWLIGLIIFSTYLVFSSLTYLSPYLSEVYVMPMTLVSALSIIRTYVIKMGASPVAGVI
                     TDKVGSSIRVMFVGFILMTVSTAAYLVIPKSTGFIWIAVINMIILSVILFGFRGIYFA
                     SVSESNISLETTGAVVGFASFIGFSPDAFYYTIAGNWLDKYGQTGYTYIFILSVVCAV
                     IGIFATYALNKINKRENKGLNNKIA"
     gene            complement(25061..26215)
                     /locus_tag="PC512_002425"
     CDS             complement(25061..26215)
                     /locus_tag="PC512_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDF2442163.1"
                     /translation="MSNNINQDLETKIIHWGHSADPTTGALATPICQTATFAAKTVEH
                     FEELCMTWGYVYTRECNPTLTELEAKLAMLENAESAISSTSGMGAITSTILALVKSGD
                     HIVSSDGIFSHTKLFMSELLSKFGVEVTFVDAVNPQNVKEAMRPNTKIVYIESPLNPS
                     LDLVDIKTIAEIAHENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLG
                     GAVAGSKELIDLVRWPSLCCFTGASLPPMSAWMILRGMKTLDMRMKKHCENGLAVAEF
                     LEEEENVELVKYPALKSHPQYELCKTQMNGLGGGVVSFKLKDGINGLTRDQASRRLMN
                     SLELATIATSLGEEHTLVQMNGENLIRIAVGLESSNDIINDFKQAIEKLK"
BASE COUNT         8153 a         5134 c         2620 g        10676 t
ORIGIN      
        1 tttcgtcaat actttttttg ttttttattt taaaaaaggt tataactttt gtttttttta
       61 ataaatataa ttaaaactaa tagatataac ccttgatatt acaaacaata catgcatata
      121 taattttacc tattttgcaa ttttattttc ataagaatat gaattagctc tcactctatc
      181 tgcccaaaca tttatactct taactttatt aacattagtt gtaccctcaa aaatatccat
      241 tgcatcctta caaaaatata tcataacatc aagaaccaaa aatccaacac aaaataaaca
      301 taaaaaatta attacttgaa acatcagaca ttcccccaat aattttttat atatagtatt
      361 ctcataaatt attcttttta ccttctcata aattattcta aatattttca taataaatta
      421 ctttcaatca tattttctaa atataaagtc tcaatcaaca aaaactaata tcaatttcta
      481 acgtttgttg gtaatttata aattaaatat ctaaaagaat ctttgaagca tataaaaagc
      541 attctacact gacattttaa ataaaattta gctatttatt gataatttaa tagctaaact
      601 ttatttaaaa cttagtagaa tgctaatatt tcttagtttt cttcttcttt atttggattg
      661 ttatcaatag gtttcatagt cgggaataat aatacatctc ttatagatgg agagttagtt
      721 aataacataa ttactctatc tatacctatt cctagtcctc ctgtaggagg tagacctacc
      781 tctaatgctt ttaagaaatc ttcatccatt tcaaaagctt catcatcacc taattctctt
      841 tttcttaatt ggtctataaa tcttcctttt tggtcaatag ggtcattaag ttcagaaaat
      901 gcattagcta actcccactt attagcaaat gcctcaaatc tatcagttct tcttgggtct
      961 tcaacatttc tcttagataa tggagatact tcaactggat gatgagttat aaatgttggt
     1021 tggattaatt tatcttctcc aaattcttca aagaaagcat ttattacttc tcctcttctc
     1081 attccaggtt ttatctctat acctttttct ctagcaactt ctagtgcctc ttcatctgta
     1141 tttatagtag aaaaatctac accagaatat tctttaacac aatcttccat actcattctt
     1201 ttccaaggtg gtgtaaagtt tatttctgtt ccttgatagt taactatcat acttcctgta
     1261 gcaacttcag ccatatgtgc aataacattt tctgttattt ccatcatatc agtatagtct
     1321 gcatatgctt gatataattc tattgcagta tattcaggat tatgttttaa atccatacct
     1381 tcatttctaa acattcttcc catttcataa actttatcaa atccaccaac aataagtctt
     1441 tttaaataca attcattcgc tattcttaaa tacattggta tatgtaaagt attatgatta
     1501 gttataaatg gtctagcatt tgccccacct gctatagtat ttaatattgg agtctcaact
     1561 tctaaaaatc ctctatcatc taagtatgct cttaatgctt ttaatgcttt tgttctaatt
     1621 aaaaaagcat tttttacttc tggatttact attaagtcaa catatctttg tctatatctt
     1681 agttcttggt cttttaatcc atgatatttt tctggtaaaa cttgtaaaga tttacatagt
     1741 aatactacag atttagcctt tacagatatt tcaccttttt tagttttaaa gatttctcct
     1801 tcaattccaa ctatatctcc aatatcatat gttgaaaata cactatattc ttcctctcct
     1861 atagcatcta gtcttacata agattggatt cttccctctt ggtcttgaat atctataaag
     1921 ccagctttcc cttgtattct cttgctcatt atacgtcctg ctatttttgt agttttaccc
     1981 tcaagagaat caaagttatc ttttatatcc atagaataat gagttctatc atatctactt
     2041 tctttaaaag gatctctacc tgattcttgt aattttttta gtttatctct tcttacttga
     2101 agtacttcac taaggtcttc ttgaatttgc gcttcttcat tgctttgttg attatttttc
     2161 atttttttcc tccaaattat cttcttattt ctaatatttc aaacttagca actccatcag
     2221 gaacttgcac ttccacaact tctttcgcag ctctacctaa aagtgctttc cctacaggag
     2281 attcgtttga tattttacca tcatatgggt ctgcttctgt cgaaccaact atagtatatt
     2341 caacctcttc atcaaattct aaatccttaa ctttaactat tgatcctatt gtaacaacat
     2401 taaggtctat tttgctttca tctatgataa cagcttttct aaccatattt tctaatttta
     2461 aaattctttc ttcaacttgt gcttgttcct ttttagcttc atcatactca gcattttcag
     2521 ataaatcacc aaaagatata gcaactttta ttctctctgc aacttctttt ctctttacaa
     2581 cctttaagtt ttctaattct tcttctaatt tatcatatcc ctcttgtgtc aataaaaact
     2641 ctttattttc ttccattata aatacaactc cttcacaaat ttcttaggaa ttttcctaat
     2701 tatattttaa aaattttata atcttttttt aatttatgcg ctatattata agtcactatt
     2761 atttttatgt caaggagtct tccatatagt actccaattt cgacacaact tcttgatagt
     2821 cttctatttt gttaatttca tcccttaatt ttgcagagtt tctaagtcct tttaaatacc
     2881 aagcgatgtg ttttctcatt tcccttacag ctacatactc tccatgttct tctactgcaa
     2941 gttttaaatg cttaatggca gtacttattt tttcgttaag agttggctct ggcaaaatct
     3001 cgcctgtatt catataatgg tttattcttt taaatatcca agggttacct tgagcacccc
     3061 tacctatcat tatagcatca caaccagttt tgtctaacat atttattgaa tcttctattg
     3121 taaatacatc accatttcct ataacaggta tactcaaatt tttcttaatc tctgcaatta
     3181 tatcccagtc tgctttgcct gtataaaact gttctctagt tcttccatgt attgctaaag
     3241 cacttattcc acaatcctct gctatctttg ctatttcaac agcatttaca ctattatcat
     3301 cccagccttt tcgaatcttt aaagtcactg gcttttttga gttcttcact actgccctca
     3361 atacctcttc tgcaagctta ggatttttca taagtgctga accatctcca tttttaacta
     3421 cttttggagc tggacacccc atatttatat cgagaatctc atttgaataa tcattcatta
     3481 tctctgctgc tcttcccata aactctggtt ctgaaccgaa tatctgaact gctacaggat
     3541 gttcttcctc ttctatctta agcatttttt tagtattttc atcatcatag caaagtgcct
     3601 taccatttat catttctgta tataaaagcc cacatccttg ttctttacaa attaatctaa
     3661 atggaaggtc tgttacacct gccataggtg atagaaaaac tttatttttc aattctaaat
     3721 ttcctatttt cattgttttt ctcctatttt tgcctttatt ttgtgattta actttaaatt
     3781 cttatttcct cattataata taccacatat agctagaaat ctatcataaa aagggaattg
     3841 gatatataac ccaattccct gtatattaat tattcttggt ttttttcata tattattctc
     3901 aatccttcta gtgttaaaaa accatctaca taatctatac ttttcgtctc tgaagcaatc
     3961 agtttagcta acccacctgt agctataacc ttaacatcat cacaattcaa ttctttcttc
     4021 atcatactta ttattttgtc aactaaacca acatatccat aaattattcc agattgcatg
     4081 gctgatacag tactcttaca aatagtcata cctggcttag ctaattctac tctaggtaat
     4141 ttagacgcac tttgaaataa cgcctcacta gatattttta ttcctggtgc tattgttcca
     4201 cccaaatatt cacctttttc agagatagca caaaatgtag ttgctgttcc aaaatcaaca
     4261 agtatacttg gtgctccata cttttctatc cctgctacag cattaactat tctatctgcc
     4321 ccaacttgtt ttggattatc atattttata tttagacctg tttttatgcc tggacctact
     4381 attaatggct gttttttaca gtactttata caaaagtttt caagagaatg cataacattc
     4441 ggaactacag atgatattat aacatcatca atatcactta tattcacatt atcataatca
     4501 aataggttac ttattaggat tccatattca tcagacgttt tttctctatc tgttttaatt
     4561 ctccagtaat taactaattt gtcaccttta tatataccta aaaccatatt agtatttcca
     4621 acatcaaata ctagaagcat atgtcattaa ccttctttct attttttgct tttcttaagt
     4681 acagtggcaa cagcagctac tactaaagcc cctactattg cttctggcac cccatttgct
     4741 gcggcaagag ccattattac ttttcctgct gaaccacttt tacccattgc atgaagatac
     4801 ttgtcagcat ataagacata tatcattcct aaaactccag ctgtatttaa cagagaacct
     4861 attgcccctg taattaaacc tgatatgtat accttatttg tagccttaat tattaactga
     4921 tatacataat aagctaatac acctatcata actcttggta atattgaaac taatggattt
     4981 ataaaaacaa aagatgttac tgttgggttt gttatagcat ttaagagact tgatatccca
     5041 aatataaatc ctattgctgc cccaactatt ggtccttcca taatagctcc aataataact
     5101 ggtatgtgca ttatagttgc ttttgtaggt ccaactggaa taaatcccaa tggagtcata
     5161 gatagcataa tagaaatagc tgatagtact cctattatag tcatctttct tacatttact
     5221 tttcttactg atgcacttgt gttcatcata aaaaatacac ctccgttcca gctcattaag
     5281 atgccggact acttaatttt ttaatttttt tcgttttttt cttataacta tgagtcaagc
     5341 taccattgta ggatgcccgc tctaacaaga ataattttat caagatgagt tgccattgtc
     5401 aacaatttga caagaaaaat atgctaattt catcatattt ctcgtttttt tactatatct
     5461 ttatatgcca ttatattttc tacactatcc gcttttttta ctgcatttat tatacttttt
     5521 tccacaacct ctacagccaa tgaacctact aatgttatat ctgcttctat ttctcctgtt
     5581 gatattgtga atattgtatc tccatcatga ggtgtatgga taggaaaaat agacttagca
     5641 tatccatcat gtcccatttg agatatcttt ttacatccag ctttggttaa cttagcattt
     5701 gttgcaatta tcccaattgt agtattatct acactaaatc cacctttact ttcaccttgt
     5761 ttcattaatt tatatgtatc aattgtttct gtctttttat catttaaagc accagctata
     5821 accttaccat tttcataaac atctccaaga gcatttacag caattaatgc agatacaatt
     5881 agaccattat ctaattttat agaatagcta cctattccgc ctttcatagc atattcctga
     5941 cctcttatct ttccaacagt ggctccacaa cctgctccat aatttccttg atttaaaata
     6001 tcagtatttg caacttcaca agctctataa cccatcttta aatctggtct acatttaaag
     6061 ctccctactc ctaaatcaaa taaaactgct cctacaacta taggcacttt acctacacct
     6121 acatcaaatc caattccttt ttcttctaag tatctactta caccacaagt ggattcaaga
     6181 ccatatgcag aacctccagc caaaactact gcatgaactt tttgaaccat atttacaggg
     6241 tctaataaat cggtttctct agtacctgga gcagagcccc ttacatcaac accgcaagta
     6301 gctccttctt cacatattac tactgtgcac ccagtaagac catttctatc ctcaacctgc
     6361 ccaaccttta agccttctat atccaaaata ttattataca tatccttttt ctcctcttat
     6421 agaaacttca cctgaaataa tttcttttat acttccatca cttctttgaa ctaataaatt
     6481 tccctcttca tttatgtcta aacatttcac tagttctcta ttatctcctt ttaatacata
     6541 tatattttta tctataattg cagaataatc tctacatatt tttaaggttt tttctttgga
     6601 attatttaca gtataatcta aatataattt ttcaaattca gtcaatacat tcctaacaat
     6661 atctactctg gataacatat acccttcttt atacaatgat gtggctttgt cagctatttc
     6721 ttgttcaaaa tccattattt taacatttat tccaattcca agaacaacat aatttgttct
     6781 ttcaatttca gcagataact ctgttaatat accacatatt ttttttccat ttaaaataac
     6841 atcatttggc cattttatta atgtatttgc tcctagattg tttaaagctt tcgttacact
     6901 tgctcctgct attaaagtta taaatggggc tttgaatggt tccatatctg gttttaatat
     6961 aatactcatc cagattcctt catgaggttt tgaatcccat cttcttccca atcgtccttt
     7021 ccccatatct tgatgttcac ttaaaatcac agtcccatct acactattta tagctatcct
     7081 tttagcatgt tcatttgttg aatctatagt gtcaagatgt tcaatatttt ttccaataaa
     7141 ctctgtatct aatttatagt aaatattctg tgggcttaat aaatcagttg gattttccgc
     7201 taatcgatac ccttttttat ttacagattc tatattatat ccctcttctt ttaaggcttt
     7261 catatgtttc catatagctg cacgtgacac ccctaattgt tttgataatt cttctcctga
     7321 aataaattca gatttattat ttaatataat ctctattatt ttatctctca tatttcacct
     7381 ctaatatgac ataatttcat gacttatttt cttctaataa ataattatac attattaata
     7441 tacttttaat actattaatt ttaaatttcc tttttaatta ttataatggt tgttttatat
     7501 tttatattga tgatttatat aattttacat tttatttaaa taattttaaa ataataaaaa
     7561 aactgaaagt atcaattaaa ttaatacatg caaatataat ttgcttatta atttaatatt
     7621 atactttcag ttttagtatt taatccacat cagataataa tcttaaaatg accaaggtct
     7681 taaaactatt tatctttatc agatttatct tctaaatttt tatttatatc aataacattg
     7741 tttctttctt cttcatcttt ttctaatttt atagttaatt gttcttcaac ttctttagaa
     7801 gaattttcct ctgtaactgc attttcaatt tcattcagag gtaactcttt attaaatgct
     7861 tttacaaatt gttctgcatc taaagtttca tatataagta aagcttgtgc tacatactct
     7921 aatctatcca tattttcttg taatatactt cttgtcttat catatgcacc atcaactata
     7981 cgctttgttt cttggtctat ctcaaaagca acttcttcag aataatttct cttacttgaa
     8041 aaactattac ctaggaatac ttcatcatca ctgtcaaatg acattggacc aagtttagaa
     8101 ctcattccat actttgttac catacttctt gcagtagctg taactctttc taagtcattt
     8161 gaagcacctg tagatacatc cttaagtact agctcttctg ctactctacc accaagtaaa
     8221 actacaatat tttctttcat ttcatttttt gtagcataga acttatcttc aacaggaagt
     8281 tgcattgtaa accctccagc tcttcctctt ggaactattg taacttgatg aacaggactt
     8341 acttcttcaa gtacatgggc acaaactgca tgccctcctt catggtatgc tgtaagtctt
     8401 ctttctttct cacttattac tttcgatttt ttagccacac ctgctataac ctttgttata
     8461 gcttcttcta tagtttccat cttaattttc ttttctcttt ttctagctgt taatattgca
     8521 gcctcattca ttaagttctc tatatcagca ggagtaaatc ctggtgttct tctagccaag
     8581 acatccattt ttacatcatc acttaatggt ttatttcttg agtgaacttt aaatatagcc
     8641 tctctacctt ttacatctgg tgtaccaaca acaacttgtc tgtcaaatct tcctggtcta
     8701 agtaaagctg ggtcaagtat atctggtcta tttgtagctg ccatgattat tataccttga
     8761 tttaccccaa atccatccat ttcaactaga agttgattaa gagtttgctc tctttcatca
     8821 tgacctccac caagacctgc acctcttttt ctaccaactg catcaatttc atctatgaat
     8881 atgatagctg gagcactttt cttagcctgt tcaaataaat ctcttactct tgaagcacca
     8941 accccaacaa acatctcaac gaaatcagaa ccacttatac tgaaaaaggg aactcctgct
     9001 tctcctgcaa ctgctcttga tagatatgtt ttaccagttc caggaggtcc taccataagc
     9061 attccttttg gtattcttgc acccaattca atatatttct taggattctt taagaaatct
     9121 actacctcct gcaaatcttc tttttcctca tctagtccag ctacatcttt aaatgtaact
     9181 ctagtttttt catcatcttt atgaacctta gcttttgatt tgccaaaact cataaccttt
     9241 ccgcctccac cttgagactg attcataaac acgaaccaaa taatcaccat gaagaatatt
     9301 aacagtaatg taggcaacat ttcgacaaac caaggtgtag atggcttagc ttcaccacca
     9361 aaagttagtt tcccagcctt agcttggtct aacacctcat ctgcaagttt atttcccatc
     9421 acttctgttg gaacatatga cttaaacttt gtatttgtat cttttatagt accttctaca
     9481 gaagtttgat ttacaaagta taatcttgat atattctcat ctgttaattc tctatatact
     9541 tcagagaatt ttaaatcttt tattttttct gtaggcttac ctgagaattg aactatacct
     9601 actataatta taaaaacaag tagataaaaa cctgcccctt ttagcaactt attcaatata
     9661 gaagccctcc tttcatacat tgctttgccc tataatttgt taaaattaat ttttaatact
     9721 tcttttgtgt tttcatcaat tttataattt tcactgattt tataatctcc aacacatatt
     9781 attccttcac tatctgtgat tataggaatt ttacatcttt cttctcttgg gatttttaaa
     9841 tctatgaata aatctttcac ttttttactt cccatagcaa gctttatctt atcaccttgc
     9901 cttctgcttc ttattactat accccctttt accttattaa aatcaaaccc tttagatgaa
     9961 ttgtctaatt tcatactctt atacctatct atgctcatta cttgggtctc aataatttgt
    10021 tttaattctt ttattttaat aaacccatta ctaggtacat tgtaataaaa ttcaatttcc
    10081 tcattaacaa tttcctcatt cgttaatatt atactgtctt tttttctata aacaaatata
    10141 tttcttggaa gagttaacat tttatttact tttgaattat cttctaaaga cattatatct
    10201 tctatatgtc tttggtcaac aaaattagta tctcctagta tatgttttat ggaatttcta
    10261 agaactctaa ctttgatagc atcatgtaag caaacaaaat cgtctaaatt tatctctaca
    10321 aagccttttt cttttatatt tgaaacttct ctaaatttag cttctgcctc tttctcaata
    10381 taatcgttat cactttttaa actattgctc atcctcacta tagattctat tacatttgaa
    10441 ttaaaattat ccttcatata tggtaaaagg tctaacctta tcttatttct agtgtatata
    10501 ttttctaaat ttgttttatc tatcctcgga tttaaattat aagcttcaca atactcctct
    10561 atctcatttc tttccacgtc taatatgggt ctaattatgc aattatctct aatataatca
    10621 attcccttta agccttttaa acctgttcct ctcatgatac gcatcataac cgtttcggct
    10681 tggtcattga gattatgacc tattgctatt ttattggctt taatcttatc cttaatttca
    10741 taaaacattt catatcttag cttccttgct ccttcttcta atgataatcc ctcattttca
    10801 caatattttg gtacattaat agactttaca aagaatataa ttcccatatc ctcacaaagt
    10861 ttagatacat ataatgcatc tttttgagct tctatccctc ttatttgatg gtttaaatgt
    10921 gctgcatata tttctatatt aaaatctttt tttaatctat ttagtacatg caataaacaa
    10981 actgaatcag gtcctccaga aagacctaaa actattttat cgcctttttg tattaaatta
    11041 tgtttattta tagtacttag taccttatca aatatcatat ttatccctct tacacttagt
    11101 tttattcact tttaagtata ctttctataa aaaaacgcta aacccttgta tcaattttaa
    11161 gaaattaaag tttaatataa atataataat accaaataaa ttaaataaaa ggtagttttt
    11221 tcactacctt tataaaattt ctggaaaata gccatagtta ttatttagta cctatgtata
    11281 tatctatttt attcctacct aaaaataaat cttgtacctt tatattatag tctattttca
    11341 attttatgtg ttccccttct tgtatattta tatctaattc tcttgtatca atatcaatta
    11401 ataaagtacc ttgtggggtc acatactttg tagtactact ttctccacat ttaaacagca
    11461 ttgttgagtt aatagcacca aactttttga tactaacttg atttttaagt atctttatag
    11521 tattagttat ttctatatct tcttcttttt ccttgtaaat aacatatatt ccatcatttt
    11581 tataaaaaat tttaccaaag gcagtcatct ctatggtgtc catatttcct ttttcatcat
    11641 attgtctagt atttatactt atttttacac tcaacgattt ttcctccata gattcttcat
    11701 ataaactagt atttttgtat ttctactttt tgaatcttat caattttttt ctttaagaac
    11761 tctcttgcta tatctgaaaa tttttcaggt atatctgata cataatattg ataagttcca
    11821 tgaatttctg tattgtttat aatattttgc acctctaaaa tcttttttaa atcctttgca
    11881 gtctctttag ctggattaac aagttttata tgctctccaa cttcttcacc tattgttctc
    11941 tttaaaatag gataatgagt acatcctaac actaaagaat ctatattttt ttctttcaat
    12001 tcttgtaaat atatctttgc tgtcagttta gccacttctg tatttgccca tccttcttca
    12061 acaataggca caaataaagg acatgcttta ttaacaattt ctatactctc atctatttta
    12121 gatatttcca agttgtatgc ttttgaactt atagttcctt cagttcctat tattcctaca
    12181 attttgtttt ttgtagaact tacagctgtt ctagctcctg cttctataac tccaattatc
    12241 ggtatatcat atttttcttg agcttctttt aagcttcttg cagtagcagt gttacatgct
    12301 ataactatag cttttacacc ttttgttttt aaaaagttta tagcttgaaa agtatattta
    12361 attatagttt ctttggatct tgaaccatat ggtattctgg cagtatctcc aaagtatatt
    12421 atatcctcat ttggtaatat cttcattatc tcttttagaa ctgttaatcc acctaatccc
    12481 gaatcaaaaa ctcctattgg tttattgttc atctttatac aacacctact ttacattttt
    12541 gtgtttaaca acaacttatt tatcgctaaa atttatattt atattcataa ttaatatatt
    12601 attacctaaa tgattattat agtttatttt acacaaaaaa taaaggagct atcttaaatt
    12661 agaaaataat ttctacaaaa agacaactcc tttcactact taaaaattta aatttatttt
    12721 gcaaacacat gatttcctat tctcatataa ggattcaatc tatttatcca tttgcaagtg
    12781 gctatttctg gattccaaaa atatactgct ttattagttg ggtcagttcc ataaagagct
    12841 tcctgagctg ctttacgtgc tgagtctgtt ggtgccatct ttattgaacc atcaagcaca
    12901 actgagaaag catttttttg atatatgact tcttctattg tgtctggaaa tctagggtcc
    12961 aatactctat ttattactac agctgctaca gcaacctgtc cctcatagct ttctcctcta
    13021 gcttctcctg caaccaactt agataataac atcaagtcat tatcagataa atttattact
    13081 tctttctttg ctatattttt ttcttgtttg tttactttct taatattttc tgttggttca
    13141 tatgcaaata cctctttaat aggcataaat ataaaagtca aagctaatag tgtagccatc
    13201 agtttactcc acctgtccat gattaaaacc actccttaca ttcttatttt taaaattttt
    13261 tctctaaatc cttgactact tcaagtactt taaatttaat ttttactcta cttgtttttt
    13321 ttggtgtatc ttgttttatt aacttatatt ctttatcagt taaaacttcc ttcaacttat
    13381 catctgtaga tttatctatc actccattag attcatcaac aaaacatagt ggagggaaca
    13441 taacacacca ccagtttttt ccttcacctt tcccaatgat aatctttaat gctttatatt
    13501 caccagctgg aagaactata ttagaatatt gtttagtagg gaaattgcta tattgtatac
    13561 ctacctttac actgtaatta tatccatttt taagaataat atttttactt atttcttcca
    13621 aactactata ttcctttttt ataatagctt cactttcttt tatacttttt gaattttgaa
    13681 gctttggctg taaatatttt attacttcat ctctaacttt tagtttaagt tcttggtctt
    13741 catctgtatt gctgtttgct ataacatgaa atcttattaa tttatcttta taatcttttg
    13801 atatattgtc tacttttttt acctcaccat ttattactat tgtcattatt gatatgactg
    13861 atataagact taatattaat agtcccaatc taatcttaat ttttctcatt gaaaattccc
    13921 cctcaagata aatttatatc atcaattatg tccaattaaa tttaatttat tcataatatt
    13981 ttttaatact aataaaaaaa gctatcttaa aatgattaca atcattttaa aatagctttt
    14041 taaaccttat attttataag tctttactaa tcatagcctt atctatcata aactgctctg
    14101 ctttttctat atgctctgta gcatacttct tggatagctc actatcacct ttaattatag
    14161 catcaagtaa atatttatgc tcttcaacaa tattatgtga tgtatcataa gcagacatat
    14221 aggtaactct aaatctatat acttgttccc acaatgagtt tattaattgg attaattttt
    14281 tattattagt tgctttaaat atacattcat gaaattctac atcaagtttt aataacgcat
    14341 ctacatcgga ttccaaagtg ctttttttaa attcttctga tatatcttta agctttttaa
    14401 tatcttcatc actaattctt tcagcggcaa gatatgctgc taagccttct aggcttgctc
    14461 ttacttctaa tacatccata atatccttta atgacatatt tgccacatac gcaccttttc
    14521 taggcaacat aacgactaaa ccttctaatt caagctttct tattgcctct ctcactggag
    14581 tcctacttac tcctaattgt tctgctagtt gcacttccat tagcctttga ccaggcttta
    14641 attttccttc taagattgct tctcttaaat tctcaaagac tacatctctt aatggcttgt
    14701 aattatccaa gttcagttta gttaaattct ccacaaattt caaccccttt ttgactgcta
    14761 ttaacaacat acacctgttt atattttttt aataattctt tttttccaat tagagcatct
    14821 tctttatttt taaatagtcc aaaaactgta ggaccacttc cactcatcat agaacctaaa
    14881 gcattatttt tcatcattac ttgttttata tcacttattt ctttgtgttt acctatagta
    14941 acattttcaa gaatatttac catgctttct gatacagctt ttatatcttc agattttaaa
    15001 cactctatca aatatttatt atttggtctt tttttaatat tattcaaatc taatccttga
    15061 taaacttctt tagtagaaac gaataagtct ggtttgcata tcaatatatt tgtatcacat
    15121 ggtaaacctt tgatgtttgt tagcttttct ccaatacctt gagctaaggc aggtcttcct
    15181 gatatacaaa aaggaacatc tgcgcccaaa ttaagtccta tttcttttaa ttcatcttca
    15241 gataatctaa gttcccatag gtgatttaaa cctactaata ctgcggctgc attagaactt
    15301 cctccagcca tccctgctgc tacaggaata tttttttcta tgaatatttc tacacctttt
    15361 tttatataaa atttattttt aagtattttg gcagctttat aaacaatatt atcttcatct
    15421 aaaggaatat ctaaactagt gctttttacc tttatttcat cttcgtctaa ttcttttatc
    15481 tttactatat cgtataaatc tatcgtttgc attatcattt caacaaaatg ataaccgtct
    15541 tgcctttttc ccaagacatc aatggataaa tttatttttg ctctactctt tagtcttata
    15601 aaatccattc tatcctcctt gtttaaagaa taatgcatca ctaacaataa tattatacta
    15661 caaaaaataa aataataggg tattataata ccctattata cttaattact ttaaattttt
    15721 taatattaat ctactaatac gacttttttt tctaaaataa gacacttacc aggcttaatt
    15781 ggttcatcaa gttttatatc attaagttct gcaatttcat tttctgttgt attgtatttt
    15841 tttgctatat tccagaaagt atctccttct ttgcatatat atacgattat gctaggagct
    15901 ttagataaat catatacacc ttggtcttct cccttgataa taaaattttc tgctttctta
    15961 tctaatgctt cagtaaatct cttaattttg ataatcaagt ctatctggtc cctattcaaa
    16021 tcaacttcga ctttatcaat acatgctgta ttaaacacag atgctgtatc agttagatta
    16081 tccatttcta tatcatgttc aaatggaatt tcctcactaa ttttataaac caattttaaa
    16141 ccttcaactg ggacaaataa aatttcaact tttatgattc cttgtataat gcttttattt
    16201 ccttcaatat aactattttc tatagacatg gttggacaaa cgcttacaat atcttttatt
    16261 tgtatatcat cattatcatt tcttatgcct tctctaacca taaatgtttc ttcactacgt
    16321 cttaaagtct tatttaattg aataggtttg tggtcaaatt ttattatctt ttgaggcgaa
    16381 tatgcatctt gtaatacttc tcttgtaact tcatctgtaa cttttacctt acaacaagcc
    16441 atacaatcta tttctaaaag acctgtgttg ctttcactat tttgcttgaa aatatgatta
    16501 aaatctgaca tagacaacaa tacttcttca gtcataccat cactaactcc agggacttct
    16561 acaaattgag taaactcaat acctactcta tccaactcta caagttcacc ctcatatgta
    16621 caagctaacg gatttatttc taatactcca ccaataataa ctttattgtc agtcactcta
    16681 ctttctttta ctttaacaca tggatttaaa cttattatag attgaatttc ctctgtgttt
    16741 attgttatag tatctcttat agaactttct gctttttcta ttccaactat atcttgaaaa
    16801 caaatttcct ttctgtgctt ttgtatgcct tccacttgcg ccacatcttt tacaatgtct
    16861 aacctttgct tttcaaacaa acttcccctt atattcataa gagctcctac tttaatcttt
    16921 ctctcattca ttatagtaca atccatatgc tctacttctg aaaataacat gtattccata
    16981 tcttgaacaa cattgtcttt ttctattact tcgtttatat ctacttttcc gtctacatta
    17041 gaaatagtat ttttatcatc tgcaatatag attacattat aattaaaact acctctgcaa
    17101 agtatcttcc catctgccat ttcaattttt ttaagtgata tgtatccttc tgtttttaca
    17161 atttcatata catctaattt tttgtctggt acaactgcct ccgcttcaat gaatgtttga
    17221 aattttccaa agtctattct attgtcaact ttaattacat ctttaattaa ttccatagtc
    17281 tacctcctta agtattataa aaatatcaca ctatatttat atttaaggag caaaaaaaaa
    17341 attacaccta tttttaaata ggtataattt taacttattt gtaatttatc ttgatctcta
    17401 aaaacttgca actttacatt agatgttaat aaatctgagt aactataaga tactctagga
    17461 tatccattac tttcatcatc taactttata acaaacacgc ttggataaac tttttctagt
    17521 ataccctctt ttgtaataat ctgctttctt cctttattag ctttcaacaa tattttcttt
    17581 cctatatgtc tctctaagct tactcttatc ttatctagag tttgaacagt agccacaata
    17641 tcaccttctt taacgtttat atgtttacat aatatcacat ataaacattt ttgtcaaatg
    17701 tttaaactaa ttattttata tattttttgc aaaaatgtca atactatttt tgaagatata
    17761 cagtataatt atgttaattt ttgctaatgt aatattgttt ttggcattgc ccatctaaat
    17821 tttcctctgg tttcagaacc accaattccc ttaacacctg taatagtctg ctctataacc
    17881 tcatcaatag gaactactac atcaattctt gaacaagcaa ttttctccac tataaaaaca
    17941 gggtctaatg catgtatcat tatccttcca ggcgaacttg catagtttgc tcctgcactt
    18001 attatttttt cataatttga ttggcatgct cctgcgaata tgacaagatt atccaaattt
    18061 ggttgccatt tacgtgcttc ttttactgtt ttaacaaaat ttgaagagtt tctatagtta
    18121 ctcatatctt ctatatctcc tctttttatt gtcattgcat catgacctgt tattactagt
    18181 atatccggat tatatttttc tagtagtgct cttacttctt tatactgatt ttgctctgaa
    18241 acagctacac ctactgcagg tattccaagt tgagcatata catccaagca aatttttaaa
    18301 tattctttat ctccatctat ctgtagtact tttccaggca ttccatatgt gttaggattt
    18361 aattgaagtt ttggaactgc tctagtcatt cttttttgtc tttctttagc ttttcttact
    18421 gacttatata ataaattttc tacattttta tctattaata tatcttttat atcaggtgct
    18481 tttactaatt ctaggtcatc aatataagca tctgctatta ctctaaatgc aattcccttt
    18541 agtatagcta ttttctcatt attttcatct acaccaaaag agactatttt aaatactata
    18601 tctttgttat gtgactttct agctacaatg tctcctacct tcatagttaa acctccaata
    18661 aatttttatc ttagtttata ctatgttcga tataaaactt tgtttcctaa tgtcaaaaaa
    18721 acatttctta taatacttct tttatcactc ttaaagcatt tttatagtat atcttttcta
    18781 tatcatcttc actaaaccct tcttttttta gaggttcata cagtttaccc atctgagata
    18841 tatcttcaat ctcaactttt gaatctattc catcaaaatc tgaccctaga gatacaacat
    18901 ctattcctcc aacatttaca atatgtttta tgtgtctaac catatcttca agtttacttt
    18961 cacttttatc acttaaaaat aagtggaaga agtttatacc tgtaactcca cctttatttg
    19021 ctaatacttt aatcatatca tcagttaaat ttctagaatg attcatcatt gctcttgaat
    19081 tagaatgtgt agcaattatt ggtttagaag aaatctttgc aatttcataa aatccaccat
    19141 ctgaaatatg agaaacatca accaacattc ccaattcatt catcttatgt accacttctc
    19201 ttccaaaatc agtaagccct ttttctctat attctacttt attatgagga aagctcaatt
    19261 cattcacatg attccaactt attgtcatca ttctaacccc taagtcgtaa aatttcttta
    19321 aattttctaa tttaccttca agtactgcac cttcctcaat agataaaaga gctgtaagtt
    19381 taccttctga ttggtttttc ataatttctt catagttagt agctaaagct atttcatcac
    19441 tatttttttt catttcctca tgaaatttat ttgccatact catgcaataa tcaaaaggat
    19501 gttttacttc ttcagtatca acaaaaagag caaatgtttg agctaatgaa tccccctttt
    19561 tcaatctgtc tatatcaaca gaatatttat tagacttaag ttcacttgtt tctacatttt
    19621 ccattaattt tgctatagta tcacaatgta aatcaataaa tttcatattt ataccccctg
    19681 tatattttat atttatatct aaaaatagaa atagttgtcc ttatagacaa ctattgacaa
    19741 ctatttttta atattctttt taatattact taatcttatt cttcttttaa gttaggtatt
    19801 acttttttaa cttcttcaat ttgatgccat gttttatcta tattattttc actaatatat
    19861 ttttttaaat cagttaaaga tgtaaaatct ttaactgata aattgtcatc atcatctgca
    19921 aatcttaaaa taaacatgag actcccttac tttccacaac atttcttata tttttttccg
    19981 cttccacatg ggcatgaatc atttcttcct atttttgctt ctttaactat tgttttagac
    20041 ttcttataag cctttattat ttcttttctt tggtctgctg gtagtatatc ttcccaacct
    20101 tgtaaattat atagccaatg agcctcaaca gttaccatat tgttatataa tttttcccaa
    20161 tctattttta tagaaacttc tttatcagct tctacttctt ctaaaactat atcttctttt
    20221 aagctttcac ttattccatc tatgaatccc atgaaaaatt cattagtagt tccaaatttt
    20281 tcagccaatt cacttacttt accttcaaca acatccattt tattatttaa tatttcattg
    20341 tatattccag cttcaacttt caaatattct tcccagaatt ttacttctgc ttcttgactt
    20401 tcatgattat cacttaaatt tctccattca gtatataaac tcatactttt tcctcctaag
    20461 tatacctata tttttatagt ttttatagta taaaatcttt tagttagatt ggaagtttct
    20521 tctttttgat tataccatat tctatttaaa gttaactctt atattatatc ataattaaac
    20581 aattctttta atacttttat agcatactct tggtttataa aataagggct tgtcgcaatt
    20641 gttattactt tggctttttt aattaagttt tttatcttgt aaaatttgag ttcaaatggt
    20701 atatagtcca tatcacttga aaatatatcc aaatctatgt caagaacaaa ctctgattct
    20761 acttctaaat caaatccata tagactatct attattatta attctgaaaa tatgttatat
    20821 tttaaagcag gttttataaa acttcccaca tttaaaactt catttgtata tctaaataca
    20881 tcttttagat tatttacatc tacatcatag ttctcaggtt ctctagtatc cttatgttgg
    20941 tctacatgca ctaacttgca tccttttgta aactcaccct ttaacaaaga ctttgcccaa
    21001 aaataaaatg catggttatg attgtcaaac acatatatct ttttatttcc caggacatat
    21061 tcgaccatat tctccaatcc ttttgctttt atttccttat tttcatctac ttcattaaat
    21121 actacctcat tgcctaacct tacatcattt aatgtaccat ttataagttt tggaacgtat
    21181 atgctcttat tttctctttt atcatatgaa aatacattat ttcctactgg tttttctata
    21241 taaaatccac tatattcata attttccata aaactttatt tcctccattg ttatataaat
    21301 atataagtta taattttaaa aattaaaatg cacttattgt aaatcatatc atctattata
    21361 gaaaacatct tatataacta aatataatat cttctctcaa tatgtattat acaataagtg
    21421 taaaatatat ttatataaaa tatactacat tcctataaca aaaccatcag cttcaattgg
    21481 aagataacta actcttctat tcaactccac ctttccaaaa aatactaccc aatatggtct
    21541 aaaaatactt tcaattttaa ctatttcaat ctctgggatt cctcccataa acctatgagt
    21601 taatctcata gccattttat ttgcctttgc ttttactctt cgttcgtcct tatcactata
    21661 ctgcacaata ttacaatcca cattttttac aacttcatat gtaggaaaat cttgtactat
    21721 actaccagaa cctgtagaac cattcactaa aatttttaat tcatttatat cattagaata
    21781 tctcctattc ttgaaaatgg atttcgtttt gtgaatttta agtgtgataa ttttaaactc
    21841 tatataatga agtctaactt catgagcata tttgttcttt aatattagct tactaaataa
    21901 agaatttttt ccacttttag ctatctctat agcttcttct tttgtaattc ttataggtaa
    21961 cgctcttata tccataaaat cattctcttt cttatttttt tcttgtcatt tttaaaactc
    22021 tatatatata atcaaaaaat attacaatta caactgacat aactccatat ggaattattt
    22081 ttccaactat aatatcattt ctagtcaata taccataaaa tataaatcct gttattaaaa
    22141 agtacaataa tactagaaaa ccgtctattc caagccattt tatttctaaa tcttttttta
    22201 ccttagacac taatttagac atagcagttt ctccttttat agattatttt gtgtatttaa
    22261 attttcacct attctattac caatcatcca tgcaataaat gaaaaaggta tagctatcac
    22321 aagaggctct aactcaaagc tctgaactgg aaatatttta aaataaccaa aagtcactcc
    22381 accaacaatc attcctaaaa taccacccat agatgttctt cttccatttc caagaagccc
    22441 acctactata ggtacaaatg ccgaacccat ccaaatactt cctacaaata tacatgcatc
    22501 atatacattt tcaaatctaa atgctacgct aagccccata actgctgcta aacatacacc
    22561 tattctagta aactttacta attgtttctg agataactct ttttttgtaa ttcttccata
    22621 tatatcattt gctaatgtag ccccagctgc tagataatag ctatccaatg ttgatattat
    22681 agaacctaaa attcctatta taaatattac tcttattcct tgtggtaatg tatctaaaac
    22741 taaagttata tatccagcag ctggagccat ttctggataa gtagctctta ctataagtcc
    22801 tgtcatagtt aacaccatgt caaaacatat ccatagtgaa aaacaggtta ataaggctct
    22861 tcttccaacc ttaggagaat ctgctgctga aaatctttga taaaaagttg ggtctgaata
    22921 agctccaaaa gaatatacaa ttaacatcaa tgctttcata gctgacatac cctttgtagg
    22981 gtgcataagc tgtggtgcat ctttgagtgc ttctgtaaga ccttgaaacc ctcctatttg
    23041 ttcaaattga cctggcataa ccatagttaa accaaatacc atacaaaaaa acaataccat
    23101 atctgtaatg gcaactccca taagcccacc aagtactgta agtacaacga ctactcctac
    23161 cattattaat cctattaatt ctttatctat tttccatgct acgttaccta tagttcccat
    23221 agcagttatt tctccaagtt gtgcacaata tataaacatc aaaattgccc caattatagc
    23281 aacatgcttg ccataaaaac tttccagtaa atcaggaact gttatattgg ttcttatatg
    23341 aatccttgga ccaacccaca atgctaaagg cattctccca atatgtgcag ctattgacca
    23401 aactgcccat gcagatattc catatatagc cgcatactct acactaccta ctgtaccaac
    23461 tcctccatac catgatgcaa ccaaagttcc tactattaag gaccatggta aacttcgatt
    23521 tcctaggtaa taactttcca tatcttttac atttctagaa aaataataac ctattcctaa
    23581 taatataaat gcaaatataa ctataatccc attttcccaa aatgttaaca tatctaatct
    23641 ccacattctt atattttaat ttttaacttt aatatctaaa tatgaacaac tctacccatt
    23701 tccataaaaa taggtagagt tatataataa ttataagtat ttaagtaatc ttgttattaa
    23761 gcaattttat tgtttaaacc tttattttct cttttattta ttttatttaa agcataagta
    23821 gcaaatatcc ctataactgc acatactaca gataaaataa atatatatgt atatcctgtt
    23881 tgtccatatt tatctaacca attacctgca atagtgtaat aaaacgcatc tggagaaaat
    23941 cctataaatg aagcaaatcc aactactgct cctgtagttt ctaaagatat attagactct
    24001 gaaacagatg caaagtatat acctctaaat ccaaataaaa ttacacttag tattatcatg
    24061 tttattacag ctatccatat aaatcctgta ctcttaggaa taaccaagta agcagctgta
    24121 cttactgtca ttaatataaa tcctacaaac attactctta tagatgaacc aactttatct
    24181 gttataacac cagcaactgg agatgctccc atttttataa cataagttct tattattgat
    24241 aaagcagaaa ctagagtcat tggcattaca taaacttctg ataagtatgg acttaaataa
    24301 gttaaacttg agaatactaa ataagttgaa aatattataa gaccaattag ccaagccttt
    24361 ggcattgtaa ctacttttaa caatgactta atacttaatc cttcatctga tgctccacta
    24421 tcttttttct cttccactaa gaaaaataga agtataccac atattataga tgctgcagaa
    24481 tataaccata ctacatattt gaatcctact gttatttcag caaatttacc aaagaagtaa
    24541 agacctataa aagaaattaa tgtacctgat acacctgata acccttcata aaaaccaaat
    24601 attcttcctt gctctgactc acttccttgc attctaacaa ccttaacaga ggctgagaag
    24661 aaagttaata ttgttgtaaa tccccataat acaaatatta aaagtatcat actatatgat
    24721 gggaatgtag agaaataaaa tccaagtatt cctgaagcaa ttaaagaaaa agttattaat
    24781 tttctaactg agaatctatc tgcaaaccat cctcctataa aataagatac cattcctact
    24841 aatccatata aactcaataa gttccctatt tgtgtatgac ttaatgctaa agcttgttgc
    24901 attgggtcat aaaatgatga tttcatatat ggtaaactat acatagctgt tgttccaaat
    24961 gccaatatga atattatcaa aaatctttta acattatttt tgctttccat tgattctctc
    25021 tccttaaaat tttattgttt ataatctcat tcatataatt ttattttaat ttttctattg
    25081 cttgtttaaa atcatttatt atatcatttg aagattctaa tcctacagct attcttatta
    25141 gattttcccc attcatttga actaatgtat gctcttcccc taagcttgtt gctattgttg
    25201 caagctctaa agaattcatt aatcttctac tagcttggtc tcttgtcaat ccattgatac
    25261 catccttaag tttaaatgaa actacacctc cacctaaacc attcatttga gttttacaaa
    25321 gctcatattg aggatgagat tttaatgctg gatactttac caattccaca ttctcttctt
    25381 cctctaaaaa ttctgctact gctaatccat tttcacaatg ctttttcatc ctcatatcta
    25441 acgttttcat accccttaaa atcatccatg cactcattgg tggtaaagat gctcctgtaa
    25501 aacaacataa acttggccat ctaactaaat ctattaattc ttttgaacct gctactgctc
    25561 cccctaaagt atccccatgt ccatttataa acttagtaag actatgtatt actaaatctg
    25621 cacctaaatc tattggtctt tgtacaattg gtgtcccaaa agtactatca actatagcta
    25681 agcttttatt ttcatgagca atttctgcta ttgtttttat atctactaag tctaatgatg
    25741 gatttaaagg actttctata taaactattt tagtatttgg tctcattgct tcttttacat
    25801 tttgtggatt tactgcatct acaaatgtaa cttcaactcc aaatttagat aacaactcag
    25861 acatgaataa tttagtgtgt gaaaatattc catctgaact aactatatgg tcaccacttt
    25921 ttaccaatgc taatatagta gatgttattg cccccatccc tgatgtacta gatatggcac
    25981 tttctgcatt ttcaagcata gccaacttag cttctaactc tgtaagagta ggattacact
    26041 ctcttgtata cacatatccc catgtcatac acaactcttc aaaatgctct actgtctttg
    26101 cagcaaatgt tgctgtttga catattggtg tagccaatgc acctgttgtt gggtctgcac
    26161 tatgtcccca atgtattatt tttgtctcta aatcttgatt aatattgtta ctcattttga
    26221 tttcctccca ttttgactta tttatacaac gttttcccta ccaaatttca tcaatttagc
    26281 ttagtcttaa tacatttttt caagtatact tttttatttg ttataatttc taaaaatatg
    26341 acacttattt tgttttttta cagttctaat tataaactct atagtaacta tagagtcaat
    26401 atgtttttga tatttttttt acaatgttta aaatagtcag tacaaaaata ggtatatctt
    26461 agaataacta aagtcatcct aagatatacc tatttttata tcacaatata aataattaca
    26521 tataagcatt agttttttta tcataaatag atttttcaag atttatcatc ttttcataaa
    26581 tat
//
LOCUS       DAMJVG010000053        26296 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.053, whole genome shotgun sequence.
ACCESSION   DAMJVG010000053 DAMJVG010000000
VERSION     DAMJVG010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 26296)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26296)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26296
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.053"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(255..398)
                     /gene="scfA"
                     /locus_tag="PC512_002426"
     CDS             complement(255..398)
                     /gene="scfA"
                     /locus_tag="PC512_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="six-cysteine ranthipeptide SCIFF"
                     /protein_id="HDF2442164.1"
                     /translation="MENKHVKTLSQATLKQSAAKGGCGECQTSCQSACKTSCTVANQE
                     CER"
     gene            complement(464..826)
                     /locus_tag="PC512_002427"
     CDS             complement(464..826)
                     /locus_tag="PC512_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04086 family membrane protein"
                     /protein_id="HDF2442165.1"
                     /translation="MGKSNYIFKGLGYAYIITLAVLLVYNLFLTFTDIGGDNITMVSS
                     FITTISAAIGGFYTSKHMKEKGLMYGLLVGLLYIVCIFLTVFLAQEKFVFEIGMIYKL
                     LLISAAGGIGGVLGVNFK"
     gene            complement(884..1177)
                     /gene="yajC"
                     /locus_tag="PC512_002428"
     CDS             complement(884..1177)
                     /gene="yajC"
                     /locus_tag="PC512_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HDF2442166.1"
                     /translation="MPQQQIIMSIGLWVVVIAIFYFLMIRPQKKKDKQLKEMRSSLSV
                     GDKVITIGGIVANVAKVEDDVVILELGPNRTKVPFEKWAIGTVKSKKEEIEED"
     gene            complement(1311..2432)
                     /gene="tgt"
                     /locus_tag="PC512_002429"
     CDS             complement(1311..2432)
                     /gene="tgt"
                     /locus_tag="PC512_002429"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HDF2442167.1"
                     /translation="MYAVRYELIKTCKQSGARLGRLHTPHGIIETPIFMPVGTQATVK
                     SMTPEELKEIGSQIILSNTYHLYMRPGHELIKRAGGLHKFMNWDKPILTDSGGFQVFS
                     LGPLRKIKEEGVEFRSHLDGSKHFLTPEKAMEIQNALGSDIMMAFDECAPYPSDREYV
                     KNSLERTTRWLKRCKDAHNNTDKQALFGIIQGGMYKDLREQSAKEITNIDLPGYAIGG
                     LSVGEPKPLMYDVLEHTTPLMPKDKPRYLMGVGSPDDLVEGVIRGVDMFDCVLPTRIA
                     RNGTAMTSQGKVVVRNATYAEDFTPLDPECDCYACKNYSRAYIRHLIKANEILGARLI
                     TTHNLHFLLNLMKQIRQAIMEDRLLDFRNEFFAKYGYEI"
     gene            complement(2511..2996)
                     /locus_tag="PC512_002430"
     CDS             complement(2511..2996)
                     /locus_tag="PC512_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442168.1"
                     /translation="MHSLQKQKKNNPILKIAFIFERVLAVVVLIAVFLGTIDVLRLMW
                     GAYIVDFQNPVQYSQLNDFLAQILLLVIGVELVVMLSLHIPGAFIEALLYAIARKMLL
                     LPKNEGMIDVLIGVIAIAGLFAIKKFLVTKDKSALNIMSIHDEEAIKEQQNKEDEDKS
                     I"
     gene            complement(3008..4033)
                     /gene="queA"
                     /locus_tag="PC512_002431"
     CDS             complement(3008..4033)
                     /gene="queA"
                     /locus_tag="PC512_002431"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HDF2442169.1"
                     /translation="MKTSDFKFDLPQELIAQVPIEDRASSRLMVLDKETGNIEHKVFR
                     DIIEYLNPGDCLVLNNTRVIPARLIGEKLETGGKIEFLLLKRTEEDTWQALVKPGKRA
                     KVGTKFSFGNGKLIGEVVDLSDEGSRIIKFHYDGIFEEILDELGNMPLPPYITARLDE
                     KERYQTVYSKHNGSAAAPTAGLHFTEELLNKIKEKGVDIAFVTLHVGLGTFRPVKVED
                     VLNHKMHSEYYMVSQEAADKINRAKENGKNVICVGTTSCRTIESACNEYGKMKETSGW
                     TEIFIYPGYKFKVLDKLITNFHLPESTLIMLVSAICGKDNVLNAYNEAVKERYRFFSF
                     GDAMIIK"
     gene            complement(4351..5370)
                     /gene="ruvB"
                     /locus_tag="PC512_002432"
     CDS             complement(4351..5370)
                     /gene="ruvB"
                     /locus_tag="PC512_002432"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HDF2442170.1"
                     /translation="MQGFEDENRIITSTMKMEDIDIENSLRPKTLEDYLGQEKSKEQL
                     SIFIEAAKSRNEQLDHVLLYGPPGLGKTTLASIIANEMGVNLRITSGPAIERAGDLAA
                     ILTNLNENDVLFIDEIHRINRSVEEVLYPAMEDFCLDIIIGKGPSARSIRLDLPKFTL
                     IGATTRAGMLTNPLRDRFGVICKLDYYTVDELSKIVLRSSSILDAEIQSNGALELAKR
                     SRGTPRIANRLLKRVRDFAQVRADGKITDKVAKDALELLGVDSLGLDFVDEKLLMTII
                     EKFRGGPVGLDTLAASIGEDRNTIEDVYEPYLLQLGFINRGPRGRVAMPLAYEHLKIP
                     YPNEK"
     gene            complement(5477..6079)
                     /gene="ruvA"
                     /locus_tag="PC512_002433"
     CDS             complement(5477..6079)
                     /gene="ruvA"
                     /locus_tag="PC512_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HDF2442171.1"
                     /translation="MYSYIKGTVEEIYIDSIVVENNGIGYKINVSSNTIMNLQVGEAT
                     KIYTKLIVREDDMSLCGFVSREELKMFELLTSVSKIGPKVALSILSFASPAQLGAYIL
                     SEDIGKLSKAPGVGKKTAERIVLELKDKVDKNNIEFEPTLLSQKPTLISQDESVDALV
                     ALGYTLSESKEAVQKCKKDGMNTEAIIKKALTYIMSKSLK"
     gene            complement(6072..6581)
                     /gene="ruvC"
                     /locus_tag="PC512_002434"
     CDS             complement(6072..6581)
                     /gene="ruvC"
                     /locus_tag="PC512_002434"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crossover junction endodeoxyribonuclease RuvC"
                     /protein_id="HDF2442172.1"
                     /translation="MIILGIDPGIAIVGYGIIEYKNSKFKVIDYGAVTTPAHMNISRR
                     LELVYKGIDTIVKNYNIDEVGMEELFFNKNVKTAITVAQARGVTMLACAHNGKPVYEY
                     TPLQVKQGVVGYGRADKAQVQQMVTSFLSLKKVPKPDDVADALAVAICHAHSNKLEKT
                     LKNIGGKYV"
     gene            complement(6924..7553)
                     /locus_tag="PC512_002435"
     CDS             complement(6924..7553)
                     /locus_tag="PC512_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442173.1"
                     /translation="MFEKKKKELFPWKISALILVGVFVLSSGVYIGTRLKHNGVQTGE
                     VVSTSANMNEKSKEAFGLNKNCEVWLQSEGENETNYKRTLTMAGIVPESLLDKTKSEI
                     VSYFKKEYPTKKIKSMDKNEIILVESKYSDNKDVQAMDVTIKGKYTIENDNGNIALYK
                     YDDSGSKTLVEKTKIRVDSLPKTVQDEIKKGVVMDTEEEAYSRLEDFAS"
     gene            7756..8079
                     /locus_tag="PC512_002436"
     CDS             7756..8079
                     /locus_tag="PC512_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1540 domain-containing protein"
                     /protein_id="HDF2442174.1"
                     /translation="MERINCNVINCSHNNSHICYADKIFINGEKAHNDRHTCCSSFLD
                     ESIYSNLSSNVNNRNCEELVCTVKNCKYNKDGSLCTLDNILVAPETDRVNLYIETCCS
                     SFECK"
     gene            8347..9201
                     /locus_tag="PC512_002437"
     CDS             8347..9201
                     /locus_tag="PC512_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442175.1"
                     /translation="MSTFYIQFLYFVIYSFIGWCCETTYCSVLQKQFVNRGFLNGPFC
                     PIYGFGALAIVATLTPFVHTIPLLFLFSIIITSIMEYCTSFILEKIFNMTWWDYSKHK
                     FNIHGRVCLENSLMFGVLSLIVMLIVHPIVVDFINSISKNVLFIFAISIEIYFVLDLV
                     ITVHTILQLNGKLKQINLIIKELKDKKEYYKLITQETIENKLESLVENRLDTLEDRFE
                     ILKEKENYRYAKNRIDELKNKLNTLLSNHKLLHRRIIKAFPNISSNKHTDILNKIKEN
                     IKSIKKDK"
     gene            complement(9387..10823)
                     /locus_tag="PC512_002438"
     CDS             complement(9387..10823)
                     /locus_tag="PC512_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HDF2442176.1"
                     /translation="MREVKPISIDILNTFKQVDEDRLNKLLADELKHLDRKIVVLDDD
                     PTGVQTVHDISVYTDWDKDSMEQGFNEKNSMFFILTNSRGFTVAQTTKAHKEISKNIV
                     DVSKKVNKDFIIISRSDSTMRGHYPLETNLLKSEVERLSEKLFQGEIIMPFFKEGGRF
                     TIDNVHYVKEGEILVPAGMTEFAKDKSFGYKSSDIGEWCEEKTNGKYKSSDMIYISSK
                     ELRELNIEAITEKLKKAEGFNKIIVNATDYVDVKVFTIAFIRAVNSGKEFMFRSAAAI
                     TKILGGVSDKELLTKDELVSKGNTNGGIILVGSHVNKTTQQLEELKNCKYPIEFIEFN
                     QHLVLQENGLKNEVKRVIKVVEEKISRGKTVAVYTRRERFDLDTNDKDKQLMISVEIS
                     DAVTSIIGMLNVRPNFIIAKGGITSSDVGTKALRVKKATVMGQIKPGIPVWMTGKESK
                     FPNMPYIIFPGNVGEISTLRESVEILMG"
     gene            complement(10894..12276)
                     /locus_tag="PC512_002439"
     CDS             complement(10894..12276)
                     /locus_tag="PC512_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HDF2442177.1"
                     /translation="MITGYGLLIAFVISIGILLVSIIKFKVNPFLALLITSIITGFMV
                     RMPINEISTTISTGFGNTLGSIGIVIGLGIIFGNILSESRATESIAKGLLAKTGEKNS
                     ALAVTTAGFLISIPVFMDAAFVIMMPIIKYVSRVTKKSLMVFVCALGVGTIVGHALVI
                     PTPGPLAVAANVNANVGSFILYSIIVAFPAALIGGWIYGKRFEKYPAYAIDENDREKN
                     LEQGKDSIKIEDDDSSKVPGFGISMFSLLFPILLILISNVFSMFLEKGSTMSGVLAFI
                     GDKNIAILLGILVAIGFLKKYINKPMGDVVIEAADSAGLILLITGSGGAFGSVINASG
                     IGNFLVDTMSGLSISVVVLGFLLSALLRISQGSATVALVTTSSILGPTILATGMSPVL
                     VGLAICAGGVGFSLPNDSGFWVLSRFSGLSVKDTLNSWTIGGTIAGVVAFIMVLLLSV
                     INGIIPLPGL"
     gene            complement(12412..13317)
                     /gene="garR"
                     /locus_tag="PC512_002440"
     CDS             complement(12412..13317)
                     /gene="garR"
                     /locus_tag="PC512_002440"
                     /EC_number="1.1.1.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-3-oxopropionate reductase"
                     /protein_id="HDF2442178.1"
                     /translation="MEGYKMKLGFIGLGIMGKPMAKNLLKDGCNLLVYDINKSAVDEL
                     ISCGAKYASVLEMGQECDIVFTILPNGTIVQDILFGMDGLAKTLKEGSIVVDMSSVTP
                     TESILCANKLKDMGLEFIDSPVSGGEPKAIDGTLAFMAGGKEEIYKKVEPFFNIMGSS
                     SILIGDNGSGSVTKLTNQVIVNLTIAAVSEAFVLAAKAGADPEKVYKAIRGGLAGSTI
                     LDAKIPMIMNRDFKPGGKISINLKDIKNVMQTAHNLDVPLPMTSQLLEIMQTLKVHGH
                     LEDDHSGIAQYFEKLAGVEIKKHNN"
     gene            13713..14384
                     /locus_tag="PC512_002441"
     CDS             13713..14384
                     /locus_tag="PC512_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2442179.1"
                     /translation="MATFKRLQEQAYDYLKELILSGEMIENEIYSETKLASEIGISRT
                     PIRDALQRLSQDGFIDIIPSKGFRIHQITANEIVEIFQIRSAIEGFCTFLITSQYKEA
                     RAVETISKLKHLLDKQKDILLGDKNLNSFAEYDTLFHTTIVSYAQNTEFDKMFNNYMY
                     RIKKLALDSLSHEGRLETTLKEHTDIFNNIANGCIEDIYRTTLIHMETPKYINLEDFC
                     NNKLF"
     gene            14487..15035
                     /locus_tag="PC512_002442"
     CDS             14487..15035
                     /locus_tag="PC512_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442180.1"
                     /translation="MIFLNEDVVTNETIDKDYAIEEVRMACKHFGDLYFYFSKVLFEE
                     FGEDKTSEILRKVLFERSEERAIAMRERAHENGDELIADNIISTTDVPFLGWVPEFEE
                     LHCPYGASWLLRFEENPWFKKFASLYCDVTDTTVAEVFTGDTSHKITKNILWGDKSCE
                     RIYFHDDKVSEGKYTYGNKNCK"
     gene            15297..15605
                     /locus_tag="PC512_002443"
     CDS             15297..15605
                     /locus_tag="PC512_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442181.1"
                     /translation="MFNKIYEKKEFIVFQVKKGYVVYNTRKSFEEGHTHLKHFEAAKT
                     AIDLAINKKIPRSKDGYYLTSLIRISDDGYYIDKLSELLYVREQKGKKEKYCNSGYQM
                     "
     gene            complement(15767..17557)
                     /locus_tag="PC512_002444"
     CDS             complement(15767..17557)
                     /locus_tag="PC512_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2442182.1"
                     /translation="MKKSKGFKKTIGRLLPFVKKYKFSFIIAIICIISAATMNALAPK
                     TEGLIITQLTKDVISIAKGVPGASVNFDYVTKILVILACIYFANAIFTYTSSFLLTNA
                     IQNTMRDLRNEVENKIRRLPISYFDSNSFGDVLSRISNDVDTISNALQQSFMQIVNSI
                     LVIILALSMMFTINIYMALIALFIIPISYFVSKFVVKKSQSRFSLQQNALGKLNGKVQ
                     EMYTGFNEIKLYGKEEDSIKEFKKVNQELCENGFKAQFISSMMNPMVSLVTYFGIAAV
                     AVVGSIYAVSGGITVGNLQAFVRYIWQINQPLSQMTQLSTVIQSSFAAIERVFEILDE
                     EEEIPDVENPVKIENVKGNVTFEHVNFGYGENSTLIEDLNAEVKSGQMVAIVGPTGAG
                     KTTLINLLMRFYDVKKGAIKIDGVDIRDMKRKDLRSMFGMVLQDTWLFNGTIFENIEY
                     GRFGATKEEIIQAAKVANVHHFITTLPDGYNMFLNEEASNISLGEKQLLTIARAFISD
                     PSILILDEATSSVDTRLELMLQKAMRNLMNGRTSFVIAHRLSTIRNADLILVMNNGSI
                     IEQGNHDELMEKGGFYEKLYNSQFADKESE"
     gene            complement(17557..19284)
                     /locus_tag="PC512_002445"
     CDS             complement(17557..19284)
                     /locus_tag="PC512_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003496244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2442183.1"
                     /translation="MKLILSYLKNYKLLIVLNILAIFSFALVELGIPTIIAKIIDNGI
                     ANQNIAYIKQMGIVIVIISIIGVVGSILLGYCSAKVSTSVTRDIRNDIFEKSQEFSHT
                     EYNKFGISSMITRTTNDAFQIQQFVNILLRTALLTPVMFIISIIMTIRTSVELSIVLA
                     ISVPFIIIGVAIIAKVSQAISSKQQKGLDKLNLISRENLTGIRVIRAFGNDDYETERF
                     EKTNTYYANVSKKLFKLMSITQPAFFLLLNIAVLAVFWISSEKINIGELQVGQLVAFL
                     EYLFHAMFSIMLFSMVFIMYPRAEVSANRIKELLNEEPLIKNPENGIKDTENKGIIEF
                     DNVTFTYPDGEASVLKDISFTAKTGETVAFIGSTGSGKSTLINLIPRFYDVTEGSIKI
                     NGVDIREYDLKALRKKIGFIPQKSLLFTGSIANNIRFGKHKAGESELEYSAKVAQAYE
                     FISKKPRKFDELISEGGANVSGGQKQRLSIARAIIRRPEIYIFDDSFSALDFKTDAIL
                     RAKLKKETKDAIVLIVAQRISSIIDADKIIVLNEGQVVGMGTHKELLKNCEIYYEIAT
                     SQLKKEELE"
     gene            complement(19529..19795)
                     /locus_tag="PC512_002446"
     CDS             complement(19529..19795)
                     /locus_tag="PC512_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase family protein"
                     /protein_id="HDF2442184.1"
                     /translation="MNLEPKKLIEQIGKEKDKKDIWIVGGGDIVKLFMKDNLIDDYYI
                     YILPIILGRGISLFKSGIDKTNLNFKKASNIGELVKLEYSKKQK"
     gene            20093..21205
                     /locus_tag="PC512_002447"
     CDS             20093..21205
                     /locus_tag="PC512_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HDF2442185.1"
                     /translation="MKISEVATPNFLLDLDQLEKNIDKIQQICTNNNKQLWPMLKTHK
                     STYIARLQKNAGASGFLVGTLDEGEALIKAGFEDIMLAYPYMGEVNINRIVTMASKIN
                     LICATDNIECAKAYSEAFSKSKIECKLLIIVDCGLHRFGVEPEKVVELATEISKLENI
                     KIVGISSHPGQVYGCSSPEGVPDVCVQEDSSMEKAYKALTDNGFNIEIVASGSTPTVE
                     SEAASKTITAVRPGNYVYYDAIQIGLGCATEDMCALTVVCTVISKNSSGYYLIDCGSK
                     CLGLDKGAHGNSSIVGYGRVCGHPELTIDSLSEEVGKIKVNGETDIKIGDRIRIIPNH
                     SCSTANLTSNLLGFRGDTIEKVIEVDIRENSKQIIL"
     gene            complement(21569..22078)
                     /locus_tag="PC512_002448"
     CDS             complement(21569..22078)
                     /locus_tag="PC512_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside recognition protein"
                     /protein_id="HDF2442186.1"
                     /translation="MSQQNTGNAIVNSKPKKTAVEIFMGGAKKGFYIGVEQILPAMIM
                     GYVIVQFLQLTGLVDILGNIFGPVMGIFGLPGESVLVLIAAFFAKAAGAATAANLFAQ
                     GLITAPQATILIMPCMLMGTLVGHYARIVLVANASTKYRMLLLAVPIFDAIVGMLIVR
                     VLLTVMGLM"
     gene            complement(22080..22727)
                     /locus_tag="PC512_002449"
     CDS             complement(22080..22727)
                     /locus_tag="PC512_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442187.1"
                     /translation="MDVTAGDNKVTWKGYLSLFVLIVLFSGVFKDSQGFLKALDFANL
                     TGSFGTIADGVDFMGKGGTGAKDGFLFALTLIPTVCFAVGLIDVVESMGGMKAASKIF
                     NPLLRPLLGIPGIAGIAFVSSFTSSDVASIMTKELFESGEITDDERTIFVAYQYAGSA
                     VILNTINTQAPLLPIALLALGPIILIEIFCKILGANLVRLIIGVRNKKNKAKEAV"
     gene            complement(22741..23913)
                     /locus_tag="PC512_002450"
     CDS             complement(22741..23913)
                     /locus_tag="PC512_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDF2442188.1"
                     /translation="MNTYLNEISKFVDENREEIVSLWKEIVNIESYTHCKESVNKLAK
                     RLKFEFEKEGLDCELVDVGDNGSTLIGTLGSNINKKPIIFSGHMDTVFETGTFGENPF
                     KIIEGKAYGPGVLDMKGGIIISLYVIKALNKIGYKERPIKIVFSGDEEIGHKDSTGAD
                     VILREAKGGLCAFNMETGLVDNSLCVGRKGRIGCNIHVKGVETHAGNDFEGGRNAIEE
                     MANKILRIQKLTNLDVGTTVSVSVIKGGRVENSIPEDCSIKVDLRFEKVEEMENVKEQ
                     VREICKETYIEGTSTEVNFISEMMPFETTEDVMRFHTFVNEVSKENGFGELNAKRLGG
                     SSDASYLTIANVPAICSFGVRGEWNHTSREYAVVDSMFERVKLISTVILNLDKFEV"
     gene            24181..25557
                     /locus_tag="PC512_002451"
     CDS             24181..25557
                     /locus_tag="PC512_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442189.1"
                     /translation="MKYKIGFLTTSYFMSDKFKQALKELNDTCEITFIELKGENPFNN
                     LPNIYYEQVDNFDGFVCSGIVPYSELIINIKDIKVPLNFLKLDERDFYKYLFKLLNSQ
                     KDIDFTKSFMDFLREDNNYYDIYSLIDSNKCPYTIKDFNIPQPVYDFKKLNDKLLEIH
                     LDLLRDNKINLSFTRNYIISCELNKLGYDCIYMVPSTESILNTFKSLVNEITLQNLDK
                     NKSATCIVTVNSSEYINEDLIFKNDEIQNQIYNTILNSLSRHGFYGVQVKKNDMKIEI
                     HTTKEMLNNMTNNYTDFFISEDLKEIKYSLNIGWGIGNTNIHAEQNARQANGKSASLN
                     GNCTFIVNDTNDTIGPLYSNKNSNNIEDSSIANKVASFIPLSNTNVSKIMCMINDRNS
                     NNVSAEILSNYMNITLRSANRILSILYKAGIATIVNTKLDNQRGRPKKIYKVDFLSFL
                     NKMQKLNS"
     gene            complement(25808..26167)
                     /locus_tag="PC512_002452"
                     /pseudo
     CDS             complement(25808..26167)
                     /locus_tag="PC512_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891108.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
BASE COUNT         8908 a         4448 c         3082 g         9858 t
ORIGIN      
        1 ttagagttta aaattaaaaa ttattctaat acatgtaatt gataaaaaat aaaatataag
       61 agtagctact ttaaaataaa tgctcttaca tgattagata tttttgcata attaaacgat
      121 aagaaatcaa atttacttct acataaatag aatatatatt tttatataat aattgaaaat
      181 aaaagaggat acctcataat gataaaagaa tcactttgag ataccctctt acaaacaact
      241 aaatcaataa ttttctatct ttcacactct tgatttgcaa ctgtacaaga agttttacaa
      301 gctgattgac aagaagtttg acactctcca catccacctt ttgcagcact ttgctttaaa
      361 gtagcttgag ataaagtttt tacatgttta ttttccattt tcaacgcctc catttctaat
      421 tgtttcctat tgattatatc ataaaactac tttaatataa actctattta aagttgacac
      481 ccaatacgcc tccaatgcct cctgctgctg atattagcaa taacttataa atcatcccta
      541 tttcaaatac aaacttttct tgtgctaaaa acacagtcaa aaaaatacat actatgtaca
      601 aaagtcctac taaaagccca tacataagtc ctttttcttt catgtgtttt gaagtgtaaa
      661 accctcctat agctgcagaa atagtagtta taaatgatga gaccatagtt atattatctc
      721 caccaatatc tgtaaatgtc aaaaataagt tatacactaa taaaacagcc aaagttatta
      781 tatatgcata tcctagacct ttaaaaatat aattagattt tcccataaaa aaacctcctc
      841 tcaaattaat atatattcga gaaaaggctt ttaaattact aatttagtct tcttctattt
      901 cttctttttt agatttaaca gttcctatag cccatttttc aaatggaact ttagttctat
      961 ttggtcctaa ttctaatatt acaacatcat cttcaacttt agctacatta gctactattc
     1021 cacctattgt aatgaccttg tctcctacac ttaggctgct tctcatttct tttaattgtt
     1081 tgtctttttt cttttgaggt ctaatcatta ggaaataaaa gattgcgatt actactaccc
     1141 atagacctat actcataatt atttgttgct gtggcattaa tttttcactc ctttgtaaat
     1201 tatactcttt tgtaaatcat aataaatgtt tatataacaa tttactttct ctatctttga
     1261 gtactattga atattatata ttaaaatgat tataattaat agtgcaaaac ctatatttca
     1321 tatccatatt ttgcaaaaaa ttcatttcta aaatcaagta atctatcttc cattatcgct
     1381 tgtcttattt gtttcattaa atttaataaa aagtgaagat tatgagtagt tattaatctt
     1441 gcacccagta tttcatttgc ttttataagg tgtcttatat aagctcttga atagttttta
     1501 caagcataac aatcacattc agggtcaagt ggagtaaagt cttcagcata agttgcattt
     1561 ctaactacta ctttaccttg gctagtcatt gcagttccat ttctagcgat acgagtaggt
     1621 agaacacaat caaacatgtc tactcctctt ataacacctt ctactaagtc atctggacta
     1681 ccaactccca ttaggtatct tggtttatcc tttggcataa gtggagttgt atgctctaac
     1741 acgtcataca taagtggttt tggttctcca acactaagtc caccaatagc atatcctggt
     1801 aaatcaatat tagttatttc tttcgctgat tgttccctta agtctttata catcccacct
     1861 tgtattatac caaataaagc ttgcttgtcg gtattattat gggcatcttt acatcttttt
     1921 aaccatcttg ttgttctttc taaagaattt tttacatatt ctctatctga tgggtatggt
     1981 gcacactcat caaatgccat cattatgtct gaacccaatg cattttgtat ttccatagct
     2041 ttttctggag ttagaaaatg ttttgaacca tctaagtgtg acctaaattc tacaccttct
     2101 tcttttatct ttcttaaagg ccctagacta aatacctgga accctccact atctgtaagt
     2161 attggtttat cccaattcat aaacttatga agaccaccag ctctttttat aagttcatga
     2221 cctggtctca tatataaatg gtatgtgtta ctaagtatta tttgtgaacc aatctctttt
     2281 aattcttctg gtgtcataga ttttacagtt gcttgagttc caactggcat gaatattggt
     2341 gtttcaataa tcccatgtgg agtgtgtaat cttcctaacc ttgcaccact ctgcttacaa
     2401 gtctttatca attcgtatct tactgcgtac ataaagttct ccttaatcat atttatttct
     2461 cattatttct taagatatat ttgtaataag ctattcatat aatttattgt ctaaatagat
     2521 ttatcttcgt cttctttgtt ctgttgttcc ttaattgctt cttcatcatg aatactcatt
     2581 atattaagag cactcttgtc ttttgttact aaaaactttt ttatagcaaa tagtcctgct
     2641 atagctataa ctcctattaa aacatctatc ataccttcat ttttaggcag tagcaacatt
     2701 tttctagcaa ttgcgtaaag taatgcctca ataaatgctc ctggtatatg aagagatagc
     2761 attactacaa gttcaacacc tattactaaa agtaatattt gtgctaaaaa atcattaagc
     2821 tgactgtatt gtactggatt ttgaaaatca actatatatg ctccccacat aagtcttaga
     2881 acatctatag ttcctaaaaa tactgctatt agaactacta ctgctaaaac acgttcaaat
     2941 ataaaagcaa tctttaatat agggttattc tttttttgtt tttgtaaact atgcatccat
     3001 tacctcccta ctttataatc atagcatctc caaaactgaa gaatctatat ctttctttta
     3061 ctgcctcatt atatgcattt aaaacattat cctttccaca aatagcactt actaacatta
     3121 ttagtgtaga ctctggtaag tgaaaattag taataagttt atctaaaact ttaaatttat
     3181 aacctggata tataaatatt tctgtccatc cactagtttc tttcatcttt ccatactcat
     3241 tacaagctga ttctatagtt ctacaactgg tagtaccaac acatattaca ttttttccat
     3301 tttcctttgc tctatttatt ttgtcagctg cttcttggct aaccatataa tattctgaat
     3361 gcatcttgtg atttaaaaca tcctctactt ttactggtct aaaagttcct aagccaacat
     3421 gtagagttac aaaggctata tctacacctt tttcttttat tttatttaac aattcttctg
     3481 taaaatgtaa tcctgctgta ggtgctgctg ctgaaccatt atgctttgaa taaacagtct
     3541 ggtatctttc tttttcatct agtctagcag tgatatatgg aggtagtggc atatttccaa
     3601 gttcatccaa tatttcttca aaaattccat cataatggaa ttttataatt cttgaacctt
     3661 catctgataa atctacaact tctccaatta gctttccatt tccaaaagaa aatttagtcc
     3721 ctacttttgc tctttttcct ggttttacta aagcctgcca agtatcttcc tctgttcttt
     3781 ttaataataa aaactctatt ttacctccag tttcaagctt ctctcctatt aatctagctg
     3841 gtataactct agtattattt aatactaagc aatctcctgg atttaaatat tctattatat
     3901 ctctaaatac tttatgttca atattacctg tctctttatc taataccatc aatcttgagc
     3961 tagctctatc ttctatagga acttgagcta taagttcctg tggtaagtca aatttaaaat
     4021 cacttgtttt caatgttaaa cttcctctct taaaatttct ccagctacaa taatatcaaa
     4081 aaaacaactt attttccaca atattaccat aatctatcaa gaaattgcta tttttaacag
     4141 acaccatatc cacaatatat agatattttt ccacgatata catgtcttat ccacaatata
     4201 tagatacaat acacacaatt tttatcgtgt ttatccacag tatctacaga tataattacc
     4261 attttgtgga tatgtttgaa tttttagcca ttttagaaat attttaattt aatgactctt
     4321 ttattttata aatactcgta taatctattt ttatttttca ttaggatatg gaatttttaa
     4381 gtgttcatat gctaatggca tagctactct tcctctagga cctctattta taaatcctaa
     4441 ttgaagcaaa tatggctcat atacatcttc tattgtattt ctatcttctc cgatagaagc
     4501 tgccaatgta tctaaaccca ctggtcctcc tctaaatttt tctattatag tcataagaag
     4561 cttctcatct acaaaatcga gacccaaact atcgactcct aaaagttcca gagcatcttt
     4621 tgccacctta tcagttattt ttccatcagc tctgacttgt gcaaaatctc taactctttt
     4681 tagtaatcta tttgctatcc ttggagtccc tcttgaacgt tttgcaagtt ctaatgctcc
     4741 attagactgt atctctgcat ctaagatgct tgaagaccta agtactattt ttgaaagttc
     4801 atcaactgta taatagtcca atttacaaat aacaccaaat ctatctctaa gtggatttgt
     4861 aagcatacca gctcttgtag tagctccaat aagtgtaaat ttaggaaggt caagtcttat
     4921 gcttctagca gatggccctt tccctattat tatatctagg caaaaatcct ccattgctgg
     4981 atataaaact tcttcaacac ttctattgat tctatgaatc tcatctataa ataaaacatc
     5041 attttcattt aaattcgtaa gtatggctgc caaatctcca gctctttcta ttgcaggtcc
     5101 tgacgtaatt cttaaattta cccccatctc atttgctatt atacttgcta gtgtagtttt
     5161 tccaagacct ggtggtccat ataaaagcac atggtctaac tgctcatttc tagatttagc
     5221 tgcttctata aatatactaa gttgttcttt ggatttttct tgacccaaat aatcttctaa
     5281 agtttttggt cttaaactat tttctatatc tatatcttcc atcttcattg tagaagttat
     5341 tatcctattt tcatcttcaa aaccttgcat ttatacccct cctctcatac ttttgaaaat
     5401 ctactttata tattttcaaa tttacataaa ctccttaaat attgttttaa aatccaaata
     5461 ttataaaatc caaatactat ttcaaggatt tactcattat atatgtaagt gctttcttta
     5521 taatagcttc tgtattcata ccatcttttt tacatttttg aactgcctct tttgattccg
     5581 acaaagtata gcctaaagct acaagtgcat ctacagactc atcttgtgat atcaaggtag
     5641 gtttttgtga taataatgtt ggttcaaact ctatgttatt tttgtctacc ttatccttaa
     5701 gctctaagac gattctttct gctgtctttt taccaacacc aggagctttg gataattttc
     5761 caatgtcttc acttaaaata tatgctccta actgtgctgg tgatgcaaat gatagtattg
     5821 aaagcgccac tttaggtcct attttagata cagatgttag taattcaaac atcttaagtt
     5881 cttccctact tacaaaacca caaagactca tatcatcttc tcttacaatt aatttagtat
     5941 atatttttgt ggcttctccc acttgtaaat tcattattgt attggatgat acatttattt
     6001 tatatcctat cccattattt tcaacaacta tactgtctat ataaatttct tctactgtac
     6061 cttttatata actatacata cttaccacct atattcttta gagttttttc aagtttgttt
     6121 gaatgagcat ggcaaatagc cacagctaaa gcatctgcaa catcatctgg ttttggaact
     6181 ttttttagac ttaaaaatga agttaccatc tgttgaactt gtgccttatc tgctctccca
     6241 tatccaacta caccttgttt tacttgaagt ggagtgtatt catatacagg cttcccatta
     6301 tgagcacatg caagcatagt aacacctcta gcttgtgcaa ctgttatagc tgtttttaca
     6361 ttcttgttaa agaataattc ttccattcca acttcatcta tattgtaatt ctttactatt
     6421 gtatcaattc ctttatacac aagttccaat cttctcgata tattcatatg ggcaggtgtt
     6481 gtaactgctc cataatcgat tactttaaac ttgctatttt tgtattcaat tataccatat
     6541 ccaactatgg ctatacctgg gtcaatcccc aatattatca ttttttaaaa ttccccctaa
     6601 aaataaaaga aataccaaaa tgtatttctc ataaaaactt atgttctaaa tcattatatc
     6661 ataaataata ttaacaaatc ataaaatgct ctatgtaaaa tataaaatca aataaaaaag
     6721 ttatatcaaa gcaagatttt acctcaatat aacttttata tttattacaa ataaattatt
     6781 gtatttttat aggaattaaa tgtgactaca attttaatac taatctattt aatactaatc
     6841 tatttaatat taaattattt attattaatt tacttagtat ttaacttact tagtatttaa
     6901 cttaaaataa tattaattta ctattaactt gcaaagtctt ctaatcttga ataggcctct
     6961 tcttcagtat ccataactac accttttttg atttcatctt gaactgtttt aggaagtgaa
     7021 tctactctta tttttgtttt ttctactaat gttttgcttc cactatcatc atatttatat
     7081 agtgctatat ttccattatc attttcaata gtatatttac cttttatagt aacatccatt
     7141 gcttgtacat ctttattatc actatattta gattctacca atatgatttc atttttatcc
     7201 atactcttta tttttttagt tggatattct tttttaaaat atgatactat ttctgacttc
     7261 gtcttatcta ataatgactc tggaactatt cctgccattg taagtgttct cttatagtta
     7321 gtttcatttt cgccttcact ttgaagccaa acttcacaat ttttatttaa tccaaaagct
     7381 tcttttgact tttcattcat attcgcacta gtacttacaa cttcaccagt ttgaactcca
     7441 ttgtgtttta atcttgtccc tatataaact ccgctactta atacaaatac tccaaccagt
     7501 attaaggcag atattttcca aggaaataat tcttttttct tcttttcaaa cattgattac
     7561 gcctcctttt tctattattt tctccaagct gtaagttttt atacaattta ggtaaatttt
     7621 agaagaaaat atatttatat ttcaaattac tctaagaata gatattttct aaaaggtagt
     7681 tttctcttaa tggttatatt cttgtaatta tatggacata atttataata aataatcgtt
     7741 taggaggtaa taactttgga aagaataaac tgtaatgtaa ttaactgttc acataacaac
     7801 agccatatat gttatgcaga taaaattttt ataaatggtg aaaaagctca caatgacaga
     7861 catacttgtt gtagttcatt tttagatgaa tctatttata gtaatttatc tagcaacgtt
     7921 aataatagaa attgtgagga attagtttgt actgtaaaaa attgtaaata caacaaagat
     7981 ggtagcttat gtacacttga taatatattg gttgctcctg aaactgatag agtaaacctt
     8041 tatattgaaa catgttgctc tagtttcgaa tgtaaatagt catagtataa atataagggt
     8101 gtcaaatgta attaaactaa catagtgtag agtatctaca actattagtt tgattatact
     8161 tgacaccctt atttatttta aataaaattt cattattata accatgttta taatgttcta
     8221 actgtaatta aatttgataa atttctataa attggtataa tcaatatgta aattgaattt
     8281 agtaaattaa tcataaaaat aaaatatcga gtatatagtg ttatactaac tagaaatgag
     8341 gtgcttatga gtacatttta tattcaattt ctttattttg taatttatag ctttatagga
     8401 tggtgttgtg aaactacata ttgttcagtt ttacaaaaac aatttgtaaa tagaggtttt
     8461 ttaaatggtc cattttgccc tatatatgga tttggagcat tagcaatagt tgctaccttg
     8521 actccttttg tacacactat tcctttgttg tttttgttta gtataattat aactagcata
     8581 atggagtatt gtacgagctt tattttagaa aaaatattta atatgacttg gtgggattat
     8641 tctaaacata aatttaatat tcacggaaga gtttgtctgg aaaactcact tatgtttggt
     8701 gtattatcat tgattgtaat gcttatagta catcctattg tggttgactt tattaactct
     8761 atctctaaaa atgtgctatt tatatttgct atatctatag aaatttattt tgttttagat
     8821 ttagttatca cagtccatac aattttacaa ttaaatggta agttaaaaca aatcaatctt
     8881 ataattaagg aattaaaaga taagaaagaa tactacaaac ttattacaca agaaactata
     8941 gaaaacaaac ttgaatcttt agttgaaaat agactggata ctttggaaga taggtttgaa
     9001 atacttaaag aaaaagaaaa ttatcgctat gctaaaaatc gtattgatga gctaaaaaat
     9061 aaacttaata ctttgctgtc taaccacaaa ttacttcata gacgtataat caaagcattc
     9121 cccaacataa gctctaataa gcatacagat attttaaata aaatcaaaga aaatattaaa
     9181 tcaattaaaa aagataaata ataaaataaa cacataagtt aaataataaa aatactaata
     9241 cataagatta aggtttagaa tattttttgt aaaatactct aaaccctaat taatatacta
     9301 ttatttttaa tcttaattta taattttagt ttattttaat tttaactcag taaatttaag
     9361 cgtttaaact tcaatacact aatatactac cccatcaata tctcaactga ttctctaagt
     9421 gtgctaatct ctcccacatt tccagggaaa attatatatg gcatattagg aaatttgctt
     9481 tctttgcctg tcatccatac tggtatacca ggttttatct gtcccattac tgtagctttt
     9541 tttactctta gtgctttagt accaacatca ctagaagtaa ttccaccctt agctataata
     9601 aaatttggtc ttacattaag cataccaatt atactggtaa ctgcatctga tatttctaca
     9661 gaaatcataa gctgtttatc tttatcattc gtatccaagt caaaacgctc tcgtctagta
     9721 taaacagcaa cagttttacc cctgcttatt ttttcctcta caacttttat aactcttttt
     9781 acctcatttt ttagaccatt ttcttgaaga actaaatgtt gattaaattc tataaattct
     9841 atcggatatt tacaattttt aagttcttct aactgttggg tagtcttatt cacatgtgaa
     9901 ccaacaagta taattcctcc attggtatta ccttttgata ctaattcatc cttagtaagt
     9961 agttccttgt cactcactcc gccaagtatt tttgttatgg cagcagcgct tctaaacata
    10021 aattccttac cactatttac tgctcgtata aacgcaattg taaatacctt tacatctaca
    10081 taatcggttg catttacaat aattttattg aatccttcag cttttttaag tttttctgtt
    10141 atagcttcaa tatttagctc tctaagttct tttgacgaaa tatatatcat atcactagat
    10201 ttgtactttc catttgtctt ttcttcacac cactcaccta tatcagatga tttatatcca
    10261 aaagatttat cttttgcaaa ttcagtcatt cctgctggta caagtatttc tccttcttta
    10321 acataatgta cattatctat agtaaaccta ccaccttctt taaaaaatgg cattattatt
    10381 tcaccctgaa ataacttctc cgataatctc tctacttcgc tttttaataa attagtttca
    10441 agaggataat gtcctctcat agtagaatca ctacgactta tgattataaa atccttatta
    10501 actttctttg atacatccac aatattcttt gaaatttctt tatgtgcttt tgtagtttga
    10561 gcaacagtaa atccccttga attggtaagt ataaaaaaca tactattttt ctcattaaaa
    10621 ccttgttcca tactatcctt atcccaatca gtataaacag aaatatcatg aactgtttgt
    10681 acacctgttg ggtcatcatc taatacaaca atttttctat ctaaatgctt aagctcatct
    10741 gcaagaagtt tatttaatct gtcctcatct acttgtttaa aagtattaag tatatctatg
    10801 ctaattggtt ttacttctct catttaaaac gcccctttat gtaatttgta tagtctaaat
    10861 gtaatttata tgatataaac aatagtttgt tatttataga cctggaagtg gtataattcc
    10921 atttataaca ctaagcaata aaaccattat aaatgctaca actccagcaa tggttcctcc
    10981 aattgtccaa gagtttaaag tatctttaac tgataatcca ctaaatcttg aaagtaccca
    11041 gaatccagaa tcatttggaa gggagaaacc aactcctcca gcacatatag caagccctac
    11101 taaaactggt gacattccag ttgccaaaat tgtaggtcct aaaattgatg atgttgttac
    11161 taaggctaca gtagcagaac cttgagaaat tctaagcaag gcacttaata agaatccaag
    11221 cactacaact gatatactaa gaccagacat agtatcaact aagaagttac ctataccact
    11281 tgcatttata acactgccaa acgcaccacc tgaccctgtt atcaataata ttagccctgc
    11341 tgaatcagca gcttcaataa ctacatctcc cataggttta tttatgtatt tctttaaaaa
    11401 tcctattgcc accaatattc caagaagtat tgctatgttt ttatctccta taaatgcaag
    11461 tactccactc attgtagaac ctttttctaa gaacatacta aatacatttg atataagtat
    11521 aagaagtatt gggaacaata aagaaaacat agaaattcca aaacctggta ctttagaaga
    11581 atcatcatct tcaattttta tgctatcttt tccctgctct aaattttttt ctctatcatt
    11641 ctcatcaata gcataagctg gatatttttc aaaacgtttt ccataaatcc atccacctat
    11701 aagagctgct ggaaaagcaa caattataga ataaagtata aaactaccta catttgcatt
    11761 tacatttgct gcaactgcta aaggtcctgg tgtaggtatt acaagtgcat gacctactat
    11821 agtcccaact cctaaggcac atacaaaaac cattagagat ttcttagtta ctctcgaaac
    11881 atacttaatt ataggcatca ttataacaaa agctgcatcc ataaaaactg gaattgaaat
    11941 taaaaaacct gctgtagtta ctgctaaagc actgtttttt tctccagtct tagctaacaa
    12001 cccctttgca atagattctg ttgctcttga ttctgaaaga atatttccaa atattattcc
    12061 aagtccaatt acaataccta tactacctaa tgtatttcca aatccagtcg atattgtggt
    12121 tgatatttca tttataggca ttctaaccat aaagcctgta attatagatg ttatcagtaa
    12181 tgccaaaaac ggatttactt taaatttaat aatcgataca agtaaaattc ctatagatat
    12241 aacaaatgct atcaaaagtc catatcctgt aatcataatc tttacccctt tatcattcta
    12301 ctttattatt tatcaatttt atttttcttt tactatgata acttaacctc gctgtattta
    12361 tataatctaa tcctaataat atgtatttaa ttatattgat atatttaaat attaattatt
    12421 gtgttttttt atttcaacac ctgccaactt ttcaaaatac tgtgctattc cactatggtc
    12481 atcttccaaa tgtccatgta cttttaatgt ctgcataatt tctaataatt gacttgtcat
    12541 aggtagtggt acatctaaat tgtgtgctgt ttgcattaca ttcttaatat ctttcaaatt
    12601 aatagatatt ttcccacctg gtttaaaatc acgattcata atcattggta tcttcgcatc
    12661 caatattgta ctaccagcta ggcctcctct tattgcctta tatacttttt ctgggtctgc
    12721 acctgctttt gctgcaagta caaatgcctc agaaactgct gctatcgtca aattaacaat
    12781 tacttggttt gtaagttttg taacacttcc actaccatta tctccaatta aaatagatga
    12841 gcttcccatt atattaaaaa atggttctac tttcttataa atttcttcct taccaccagc
    12901 cataaaagca agtgtaccat caatcgcttt tggctcccct ccacttactg gtgagtctat
    12961 aaattctaag cccatatctt ttaatttatt tgcacacaat atggattctg taggagtaac
    13021 tgaactcata tcgactacta tacttccttc ttttaaagtt tttgccaatc catccatccc
    13081 aaacaatata tcctgcacaa tagttccatt tggaaggatt gtaaatacaa tatcacattc
    13141 ttgacccatt tctaaaacac ttgcgtattt tgctccacat gatataagtt catccacagc
    13201 agatttatta atgtcataca ccaaaagatt acatccatct tttaataaat tttttgccat
    13261 tggctttccc attattccta atccaataaa tcccaatttc attttataac cctccatatc
    13321 ttcacatttt tgaaaacgtt ttttatgttt tagagtatac tacataccag tataccggtc
    13381 aatataaaat ataaaagtat ttattttaac aataaatagt aatttttaaa gtcatttatt
    13441 atatttagtc atcctatata agttttaata catactattg ttttcaaata taatatacta
    13501 cttttacagt tttgtatttt aactaatttc aattagtttt aattaatctg cctttaatgt
    13561 taatcatgct tcacacttca ataatttttt atatttttta atcttatctg caatttaaat
    13621 tgcaaaagat tgaccttatt ttcactatgt tgtatgctta aaattatata agtttttgta
    13681 tttttatatt gtttaggggg gtattattaa gtatggctac atttaaaaga ttacaagaac
    13741 aagcatatga ctacttaaaa gaattgatac tatctggaga aatgatagaa aatgaaatat
    13801 attctgaaac aaaacttgct agtgaaatag gtatctctag aacacctata agagatgctc
    13861 ttcaaagact tagtcaagat ggatttatag atataatccc aagcaaagga tttagaatcc
    13921 atcaaattac agcaaatgaa attgtagaga tattccaaat acgctctgca atagaaggat
    13981 tttgtacttt tttaattaca agtcaataca aagaagctag agcagtagaa actataagta
    14041 aattaaaaca tcttttagat aaacaaaaag atattttatt aggtgataaa aatttaaact
    14101 catttgcaga atacgataca ttatttcaca caactatagt ttcatatgct caaaatactg
    14161 aatttgacaa aatgtttaac aattatatgt acagaataaa aaaattagct ctcgattcat
    14221 tgtcacatga aggaaggctt gaaacaacat taaaagagca cacagatatt tttaataata
    14281 ttgcaaatgg atgtattgaa gatatttaca gaactactct cattcatatg gaaactccta
    14341 aatacattaa tttagaagat ttttgtaaca ataagttatt ttagcattat actttcattt
    14401 attaaaaata tatctatctc aaattaattt cctaatttat aaaaaatatt ctataattat
    14461 attgtaacta atacttattc taaggagtga tttttttgaa cgaagatgtt gtaactaatg
    14521 aaactattga caaagattat gctattgaag aagttcgtat ggcatgcaaa cattttggtg
    14581 atttatattt ttatttttcc aaagtgttat ttgaagagtt tggtgaagat aaaactagcg
    14641 aaatattaag aaaagtttta tttgaaaggt ctgaagaaag agctattgct atgagagaga
    14701 gagctcatga aaatggagat gaattaattg cagacaatat tattagcaca actgatgttc
    14761 catttctagg atgggttcct gaatttgaag agttacattg cccctatgga gcttcctggc
    14821 ttttaagatt tgaggaaaat ccttggttta aaaaattcgc ttctctttac tgtgatgtta
    14881 cagatactac tgtagctgaa gtatttacag gagatacgtc ccataaaata acaaaaaaca
    14941 ttctatgggg agataaaagt tgtgaaagaa tatatttcca tgatgacaag gtatctgaag
    15001 gtaaatatac ttatggaaat aaaaactgta aataaataat ttaaattttc tatattcata
    15061 tactatattt tgtacttttt catataaata ttataactag tcttttattt tacttttgtt
    15121 taacctaaag ataatttact tttaatctat atgaattatc atataaataa tcagaaagtt
    15181 atctttataa attatagttt tagatttata atttataaaa tatttatgtt ctttgtaaaa
    15241 ttttttagaa gcttctaatg ttatgctata aaactatctt gagaagggct gattgaatgt
    15301 ttaataaaat atatgaaaag aaagaattta tagtttttca agttaaaaaa ggttatgtag
    15361 tttataatac tagaaagagt tttgaagaag gtcatacaca tttaaagcat tttgaagcag
    15421 caaagacagc tattgattta gcaataaata aaaagattcc tagaagcaaa gatggatatt
    15481 atctgactag tttaattcgc ataagtgatg atggttatta cattgataag ttaagcgaat
    15541 tgttatatgt tagagaacaa aaaggtaaaa aagaaaagta ctgtaattct ggttatcaga
    15601 tgtaacaaga ctagttgtga attataagta ccaatcataa gtacctttgg tcttaaaatc
    15661 aaagagtatc agtaaatcta taaaaaaaca acttactgat actcttttta attatatgat
    15721 taatatttga atttgataca aaattttata caaaagttta tgttatctat tctgattctt
    15781 tgtctgcaaa ttggctatta taaagcttct cataaaatcc acccttttcc attaattcat
    15841 catgattccc ctgctctata atacttccat tattcataac taaaatcaag tcagcattgc
    15901 gaattgtaga aagtctatgt gctataacaa aactagttct accattcata agatttctca
    15961 ttgctttttg aagcataagt tccagcctag tatcaacaga actcgtagct tcatcaagta
    16021 tcaatattga agggtctgat ataaaagctc tagctatggt taaaagctgt ttttccccta
    16081 gagatatatt agatgcttct tcatttaaaa acatattgta tccatctgga agagtggtta
    16141 taaagtgatg aacatttgct acttttgctg cttgtataat ttcttcttta gtagctccaa
    16201 atctaccata ttctatattt tcaaaaatgg ttccattaaa taaccatgta tcttgaagca
    16261 ccataccaaa cattgaacgc aaatctttac gtttcatatc tcttatatct actccatcaa
    16321 ttttaatagc acctttcttt acatcataaa acctcatcaa taagtttatt aatgttgttt
    16381 tacctgctcc agtaggtcca acaatagcta ccatctgacc actttttact tctgcattta
    16441 aatcttctat taaagttgaa ttttctccat atccaaaatt aacatgctca aatgtaacat
    16501 ttccttttac attttctatc ttaactggat tttcaacatc aggtatttcc tcttcttcgt
    16561 ctaaaatttc aaatacacgt tctatagctg caaaagaaga ttgtattact gtagataact
    16621 gagtcatttg tgaaagtggc tgatttatct gccatatata acgcacaaat gcttgtaaat
    16681 ttcctactgt tattcctcca cttactgcat atatagaacc gacaactgcc acagctgcaa
    16741 ttccaaagta agttactaat gaaaccatag gattcatcat acttgatata aattgtgcct
    16801 taaatccatt ttcacaaagt tcttgattta cttttttaaa ttcttttata gaatcttctt
    16861 ctttaccata tagttttatt tcattaaatc cagtatacat ttcttgtact ttcccattta
    16921 attttccaag agcattttgt tgcaatgaaa atctactttg agattttttt actacaaatt
    16981 tagatacaaa ataactaatt ggaattataa aaagagctat aagagccata tatatattaa
    17041 ttgtaaacat cattgaaagt gccaaaatta tgactaagat tgagtttaca atttgcataa
    17101 aactctgctg caatgcattt gatattgtat ctacatcatt tgatatacga cttaatacat
    17161 ctccaaaact attactatca aaataactaa taggcaatct tcttatttta ttttcgactt
    17221 catttcttaa atctctcatt gtgttttgaa tagcattggt aagtagaaaa cttgaagtat
    17281 acgtaaaaat tgcattggca aaatatatac atgctaaaat caccaatatt tttgttacat
    17341 aatcaaaatt tacggaagcc cctggtactc cttttgcgat actaattaca tctttagtca
    17401 attgtgttat tatcaatcct tcagttttag gtgcaagtgc attcatagta gctgctgaaa
    17461 ttatacatat aatagctata ataaaggaaa atttatattt ctttacaaat ggaagaagtc
    17521 taccaattgt tttcttaaaa cctttagact ttttcattat tctaattcct ccttttttaa
    17581 ctgagatgtt gcaatttcat agtatatttc acagtttttt aataattctt tatgagttcc
    17641 cattcctaca acttgtcctt cattgagtac tataatctta tcagcatcaa taatagaact
    17701 aattctctgg gcaacaatca atacaattgc atcttttgtt tccttcttca atttagcacg
    17761 aagtattgca tcagttttaa agtcaagtgc agaaaaacta tcatcaaaaa tgtatatttc
    17821 aggtcttctt ataatagccc ttgcaataga aagtctttgt ttttgacctc ctgatacatt
    17881 tgctccacct tcactaatca attcatcaaa ctttctaggt ttttttgata taaactcata
    17941 tgcttgtgca acttttgcgg aatattctaa ttctgactct cctgccttat gtttcccaaa
    18001 tctaatatta tttgctatgc taccagtaaa aagcagtgat ttttgaggta tgaatcctat
    18061 cttttttctt aaagctttta aatcatattc tcttatatct actccattta tcttaatact
    18121 accttctgtt acatcataaa atctaggtat caagttaatt agagtacttt tcccactacc
    18181 agtacttcct ataaaagcaa ctgtttcacc tgtttttgca gtaaatgaaa tatccttaag
    18241 tacagaagct tctccatctg gataggtaaa agttacatta tcaaattcta tgataccctt
    18301 attttcagta tccttaattc cattttcagg attttttatc aatggttctt catttaaaag
    18361 ttcttttatt ctatttgcag atacctctgc tcttggatac ataataaata ccattgaaaa
    18421 aagcataatt gaaaacatgg catggaaaag atattccaaa aatgcaacca actgtccaac
    18481 ttgaagctct ccaatattta tcttctcact tgaaatccaa aatacagcca aaacagctat
    18541 atttaatagt aaaaagaatg ctggttgagt aattgacata agcttaaata gtttcttaga
    18601 aacattagca taatatgtat ttgttttttc aaatcgctct gtttcataat catcatttcc
    18661 aaaagctcta attactctta ttccagttaa attttctctc gatataaggt ttaatttatc
    18721 tagtcctttt tgttgttttg aagatattgc ctgagatact tttgctatta ttgctactcc
    18781 aataattata aaaggtactg atatagccaa tactatagaa agttccacac ttgttctaat
    18841 tgtcattatt atacttataa tgaacataac tggagttaat aaggcagtcc ttagtagtat
    18901 attaacaaat tgttgaattt gaaatgcatc attcgttgtt cttgtaatca ttgaagaaat
    18961 tccaaattta ttgtattcag tatgtgaaaa ttcttgtgat ttctcaaata tgtcatttct
    19021 tatatctctg gttacacttg ttgatacctt agcagaacaa taacccaaca atatactacc
    19081 tacaacccct ataatagaaa taataacaat cactattccc atttgtttta tgtaagctat
    19141 attctgattt gcaataccat tgtcaattat tttagctatt atagttggaa tccccaactc
    19201 gactaatgca aaactaaata tagccagtat gtttaatact attaataact tataattctt
    19261 taaataactt aaaattaatt tcatattttt ctcctttctt aatttttgag atagtgtaat
    19321 catgtaataa tactaaattt ataaatgctt aattttataa aaaaaggaga aaagagttaa
    19381 cgcactctct tctccagcat attcttttta atacaccctc cgacaagtcg cttatatgtt
    19441 aacatatttg acaagtaatg tcaattcata tagccaaaag tcttttaaat gcttcatttc
    19501 ataacattgt aacaaattgg catgtaattt atttttgttt tttactgtat tccaatttta
    19561 caagttctcc aatattacta gctttcttaa aattcaaatt agtcttatct ataccagact
    19621 taaatagtga aatccctctc cccaatatta ttggcaatat atatatataa taatcatcaa
    19681 ttaagttatc tttcataaat aattttacta tatcgcctcc accaactatc caaatatctt
    19741 ttttatcctt ctcttttcca atttgctcaa ttaatttttt aggttctaaa ttaatttata
    19801 gtgtgattat tctatgtaaa catcactttt ttactcattc aataataccc tattaataaa
    19861 tcctcaaact aatttaaata aactttgcat aaaattaaaa atatattata taaataattt
    19921 aaaaccacac taacttattg aaaattctaa ttattacaaa taaatattgc tctctgttaa
    19981 cgctagttct ataatataat tataagctat taatattata aagacgatat tactaatata
    20041 ataattataa tacttatagt taatttactt ttgttgaaag gtggtaaata acatgaaaat
    20101 ttcagaagtc gctactccaa attttttgct agatttagac cagttagaaa agaatataga
    20161 taaaattcaa caaatttgta caaataataa taaacaactt tggcctatgc ttaagacaca
    20221 taaaagtact tacatagcga gacttcaaaa aaatgcaggt gctagtggtt ttctagttgg
    20281 aacacttgat gaaggtgaag ctctgataaa agcaggtttt gaagatatta tgttggctta
    20341 tccttacatg ggagaagtaa atataaatag aattgtgact atggcatcaa aaataaattt
    20401 aatctgtgct acagataata tagaatgtgc taaggcttat agtgaagctt tttctaaatc
    20461 aaaaatagag tgcaagctac ttattattgt agattgtggc ttacaccgtt ttggggttga
    20521 accagagaaa gtggttgaac ttgctactga aatttctaag ctagaaaaca taaagattgt
    20581 tggtataagt tcgcatccag gtcaagtgta tggttgtagt tctccagaag gtgttccaga
    20641 tgtttgtgtt caagaagatt cttctatgga gaaagcatac aaagctctaa ctgataatgg
    20701 atttaatata gaaattgtcg cttctggtag tactccaaca gttgaatctg aagctgcttc
    20761 taaaactata actgctgtaa gacctggaaa ctatgtatac tatgatgcta tacagatagg
    20821 tttaggttgt gctactgaag atatgtgtgc tcttactgtt gtgtgcactg taatctcaaa
    20881 aaatagcagt ggatactatt taattgattg tggaagtaag tgccttggac ttgataaagg
    20941 tgcacatgga aatagtagta ttgttggtta tggtagggta tgtggacatc cagaacttac
    21001 tattgattca ctttcagaag aagttggaaa aattaaagta aatggtgaaa ctgatataaa
    21061 aattggtgat agaataagaa ttatacctaa tcattcttgt tccactgcaa acttgacaag
    21121 taatttatta ggttttagag gagatacaat agaaaaagtc atagaagtag atattcgtga
    21181 aaattcaaaa caaatcatcc tttaaaaaca gatttattct gatattaaca tgaaagtata
    21241 tttttcttaa aattatttct aataactaat gttaatgttg gataaataaa aaacataaat
    21301 tctagaaata taaatttaaa agaagaggct gtctcaaaat agagataagc ctctctttca
    21361 ttgttgaaat tatgaaaata tacttgattt catacaaaaa gagtatctca tgaactaaaa
    21421 agttcacttt gagatactct ctttttttaa ttaatataca cattaattac tatcttagtt
    21481 tattactata tatcaattac tactcattaa tccttgtata tattaattct tatatatcat
    21541 ttatagttag gttataattt tatgttattt acattaatcc cataacagtg agtaaaactc
    21601 ttactattaa catccccact attgcatcaa atataggaac tgccaacagt aacattctat
    21661 acttagtact ggcatttgct acaagcacta ttctggcata atgaccaact agagtaccca
    21721 ttaacataca tggcataatt aatatggttg cttgtggtgc agtgattaga ccttgtgcaa
    21781 ataagtttgc agctgtagct gctcctgctg ccttagcaaa gaatgctgct atcaaaacta
    21841 aaacagattc cccaggtagt ccaaaaatac ccattactgg tccaaaaata tttcctaaaa
    21901 tatcaactaa accagttaat tgtaaaaact gcactattac ataacccatt atcatggctg
    21961 gtaatatctg ttcaacacct atgtaaaaac ctttttttgc tccccccata aatatctcaa
    22021 cagcagtttt cttaggttta ctatttacaa ttgcatttcc agtattttgt tgactcatac
    22081 tacacagcct ccttagcctt attcttttta tttcttacac ctatgattaa tctaactaga
    22141 ttagcaccaa gtattttaca gaatatctct ataaggatta ttggacctaa tgccaataat
    22201 gctattggta aaagtggagc ttgagtattt attgtgttca gtataacagc tgaaccagca
    22261 tattgatatg ctacaaatat agttctttca tcatctgtta tttccccact ttcaaataat
    22321 tctttcgtca ttattgaggc tacatctgaa ctagtaaatg aagatacaaa tgctattcct
    22381 gctattccag gtataccaag cagaggtcta agcaatggat taaatatctt tgatgccgct
    22441 ttcattcctc ccatagattc aactacatct ataagaccta cagcaaaaca gacagttgga
    22501 atcaaagtca gagcaaataa gaaaccatct tttgctcccg ttcctccttt acccataaag
    22561 tctacaccat ctgcaatagt accaaatgaa cctgtcagat tagcaaaatc taatgcttta
    22621 aggaagcctt gactatcttt aaacactcct gaaaataata ctatcaatac aaataaagat
    22681 aaataccctt tccatgttac cttattatct ccagctgtta catccatata aaatccccct
    22741 ttatacctca aatttatcta agtttaaaat aactgtagaa attaatttca ccctctcaaa
    22801 catagaatct actactgcat attctcttga tgtgtggttc cattcccctc ttacaccaaa
    22861 tgaacagatt gcgggaacgt ttgcaatagt caaataacta gcatctgaac tacctccaag
    22921 tctcttagca tttaattctc caaatccatt ttcttttgac acttcattta caaatgtatg
    22981 aaatctcata acatcttctg tagtttcaaa tggcatcatt tcacttataa aattaacttc
    23041 tgtagaagtt ccttctatgt aagtttcttt acatatctct ctaacttgtt ctttaacatt
    23101 ctccatttct tctacttttt caaatctaag gtctactttt atactacaat cttctggaat
    23161 agaattttcc actcttccac ccttaatcac acttacactt actgtagttc caacatctaa
    23221 attagtcaat ttttgtatgc gtagtatctt attagccatt tcttctatag catttcttcc
    23281 accttcaaaa tcattacctg cgtgtgtttc tacacctttt acatgtatat tacatcctat
    23341 tcttcctttt ctacctacac acaaactatt atctactaat ccagtttcca tattaaaagc
    23401 acaaagacca ccttttgctt ccctcaatat aacatctgca cctgttgaat ccttatgtcc
    23461 tatctcttca tctccagaaa atactatttt tattggtctt tctttgtatc ctattttatt
    23521 taatgcttta ataacatata aggaaattat tataccaccc ttcatatcta aaacacctgg
    23581 gccatatgct tttccttcta ttattttaaa tggattctct ccaaatgtac ctgtttcaaa
    23641 gacagtatcc atgtgacctg aaaaaattat aggcttttta tttatattag aaccaagtgt
    23701 acctatcaat gtactaccat tatctccaac atctactaac tcgcaatcta aaccttcttt
    23761 ttcaaactca aactttaatc tcttagccaa tttatttacg ctttctttac aatgtgtata
    23821 gctttctata ttaacaatct ctttccataa tgaaactatt tcttctctat tctcatcaac
    23881 aaacttagaa atttcattta aatatgtatt cataatcttc tcctttattt tcaaataaaa
    23941 tgtatttctt tcctaaaatc taagtttatt ttaggaaatc ttaaaagact agtccttaat
    24001 tacaaaatag cacaattatt cttgacagtc aacatatttt tcagtctttt ttatattttc
    24061 tgatttttct ttaaattttc cttttgtaaa ataaattgac gcgttttatc tactattata
    24121 aaatgaggtt ataaattgat tgattagtta ctatactctc gaaattttaa aggaggtttt
    24181 atgaaatata aaattggttt tttgacaaca tcttatttta tgtcagataa gtttaaacaa
    24241 gctcttaaag aattaaatga tacttgtgaa attacattta ttgagctcaa aggggagaat
    24301 ccttttaata atttacctaa tatatactat gagcaagtag ataattttga tggatttgta
    24361 tgcagtggta tagttccata tagtgaactt ataataaata taaaagacat aaaagttcca
    24421 ttaaattttt taaagcttga tgaaagagat ttttataaat acttattcaa attattaaat
    24481 agccaaaaag atattgactt tacaaaatca tttatggatt ttttaagaga ggacaacaat
    24541 tattatgata tatattcatt aatagactct aataaatgtc catatacaat taaagatttt
    24601 aatatccctc aacctgtata tgactttaaa aaattaaatg ataaattatt ggaaatacat
    24661 ttagacttat tgcgagataa taagattaac ctttctttta ctagaaatta catcattagt
    24721 tgtgaactta ataaacttgg atatgattgt atttacatgg ttccatctac agaatcaatc
    24781 ctgaatacat ttaaatctct ggtgaatgaa ataacattac aaaacttaga caaaaataaa
    24841 tctgcaactt gtatagttac agtaaatagt tcagagtaca taaatgaaga tttgatattt
    24901 aaaaatgatg agatacaaaa tcaaatatat aacactatat taaattctct atcaagacat
    24961 ggattttatg gagttcaggt caaaaaaaat gatatgaaaa tagagataca cactactaaa
    25021 gaaatgttaa acaatatgac caataactat acagattttt ttatttcaga agatttaaaa
    25081 gaaattaaat atagcttaaa tataggttgg ggcattggaa atacaaatat tcatgcagag
    25141 caaaatgctc gtcaagctaa tggtaaatct gcttctttga atggaaactg tacttttata
    25201 gtaaatgata ctaatgatac aataggccct ttatattcaa ataaaaattc taataatatt
    25261 gaagatagct caatagccaa taaagttgct tcttttatac ctctatctaa tacaaatgta
    25321 tctaaaatca tgtgtatgat taatgataga aattcaaata atgtgtcagc agaaatatta
    25381 tcaaactata tgaacataac tcttagaagt gctaatagaa tattgagtat cttatataaa
    25441 gcaggaattg caactattgt aaatacaaaa ctcgataatc aaagaggaag gcccaaaaaa
    25501 atatataaag ttgatttctt atcttttcta aataagatgc agaaattaaa ttcttaatat
    25561 ttaatttttt aataagaaca atgtattttc tctaatttta aagaatcaaa atgtttaaat
    25621 tttattagaa tatacaactt tttactttaa aatacctaaa ccttttatca gtgaaataaa
    25681 ccataatata tcgtaactta ttagaaaaac aaaataattt catatacaaa taataaaata
    25741 gccactacaa tccataattt gcagtggcta ctttttacac tatcacttat tacttaattt
    25801 ttaaaaatta attgtatttt ttaaataatt tatacatacc tattatcagt aaagcaataa
    25861 atacaagtat atctataaaa ataattattg taacatgtct ggcaatattg taaataaaaa
    25921 gtatagagaa tatttctata gacaacgcta caaaacacat aaaattcgtt aaataatctg
    25981 caatagtgtc actataaaaa gcatgtattt gtaaccatct ccatataaat ggacgtaaaa
    26041 ggattctgaa tacaacacaa atgacagggt aggcataaat aaatttttta tctacataat
    26101 tagctacacc attattccat tggataggaa tttgaggtgg caactttgga aatactgtta
    26161 ttgcaattta aacactacct ctctattcta ttaatttata actataatat agtcttaaat
    26221 attttcactc tataaaattg tatatttagt atatcttaaa atcaaactaa ttatctttta
    26281 taagttttca tacaat
//
LOCUS       DAMJVG010000054        25929 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.054, whole genome shotgun sequence.
ACCESSION   DAMJVG010000054 DAMJVG010000000
VERSION     DAMJVG010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 25929)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25929)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25929
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.054"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            115..669
                     /gene="tcdR"
                     /locus_tag="PC512_002453"
     CDS             115..669
                     /gene="tcdR"
                     /locus_tag="PC512_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin sigma factor TcdR"
                     /protein_id="HDF2442190.1"
                     /translation="MQKSFYELIVLARNNSVDDLQEILFMFKPLVKKLSRVLHYEEGE
                     TDLIIFFIELIKNIKLSSFSEKSDAIIVKYIHKSLLNKTFELSRRYSKMKFNFVEFDE
                     NILNMKNNYQSKSIFEEDICFFGYILKELSGIQRKVIFYKYLKGYSDREISVKLKISR
                     QAVNKAKNRAFKKIKKDYENYFNL"
     gene            987..8087
                     /gene="tcdB"
                     /locus_tag="PC512_002454"
                     /gene_synonym="toxB"
     CDS             987..8087
                     /gene="tcdB"
                     /locus_tag="PC512_002454"
                     /gene_synonym="toxB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_074049122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin TcdB"
                     /protein_id="HDF2442191.1"
                     /translation="MSLVNRKQLEKMANVRFRTQEDEYVAILDALEEYHNMSENTVVE
                     KYLKLKDINSLTDIYIDTYKKSGRNKALKKFKEYLVTEVLELKNNNLTPVEKNLHFVW
                     IGGQINDTAINYINQWKDVNSDYNVNVFYDSNAFLINTLKKTVVESAINDTLESFREN
                     LNDPRFDYNKFFRKRMEIIYDKQKNFINYYKAQREENPELIIDDIVKTYLSNEYSKEI
                     DELNTYIEESLNKITQNSGNDVRNFEEFKNGESFNLYEQELVERWNLAAASDILRISA
                     LKEIGGMYLDVDMLPGIQPDLFESIEKPSSVTVDFWEMTKLEAIMKYKEYIPEYTSEH
                     FDMLDEEVQSSFESVLASKSDKSEIFSSLGDMEASPLEVKIAFNSKGIINQGLISVKD
                     SYCSNLIVKQIENRYKILNNSLNPAISEDNDFNTTTNTFIDSIMAEANADNGRFMMEL
                     GKYLRVGFFPDVKTTINLSGPEAYAAAYQDLLMFKEGSMNIHLIEADLRNFEISKTNI
                     SQSTEQEMASLWSFDDARAKAQFEEYKRNYFEGSLGEDDNLDFSQNIVVDKEYLLEKI
                     SSLARSSERGYIHYIVQLQGDKISYEAACNLFAKTPYDSVLFQKNIEDSEIAYYYNPG
                     DGEIQEIDKYKIPSIISDRPKIKLTFIGHGKDEFNTDIFAGFDVDSLSTEIEAAIDLA
                     KEDISPKSIEINLLGCNMFSYSINVEETYPGKLLLKVKDKISELMPSISQDSIIVSAN
                     QYEVRINSEGRRELLDHSGEWINKEESIIKDISSKEYISFNPKENKITVKSKNLPELS
                     TLLQEIRNNSNSSDIELEEKVMLTECEINVISNIDTQIVEERIEEAKNLTSDSINYIK
                     DEFKLIESISDALCDLKQQNELEDSHFISFEDISETDEGFSIRFINKETGESIFVETE
                     KTIFSEYANHITEEISKIKGTIFDTVNGKLVKKVNLDTTHEVNTLNAAFFIQSLIEYN
                     SSKESLSNLSVAMKVQVYAQLFSTGLNTITDAAKVVELVSTALDETIDLLPTLSEGLP
                     IIATIIDGVSLGAAIKELSETSDPLLRQEIEAKIGIMAVNLTTATTAIITSSLGVASG
                     FSILLVPLAGISAGIPSLVNNELVLRDKATKVVDYFKHVSLVETEGVFTLLDDKIMMP
                     QDDLVISEIDFNNNSIVLGKCEIWRMEGGSGHTVTDDIDHFFSAPSITYREPHLSIYD
                     VLEVQKEELDLSKDLMVLPNAPNRVFAWETGWTPGLRSLENDGTKLLDRIRDNYEGEF
                     YWRYFAFIADALITTLKPRYEDTNIRINLDSNTRSFIVPIITTEYIREKLSYSFYGSG
                     GTYALSLSQYNMGINIELSESDVWIIDVDNVVRDVTIESDKIKKGDLIEGILSTLSIE
                     ENKIILNSHEINFSGEVNGSNGFVSLTFSILEGINAIIEVDLLSKSYKLLISGELKIL
                     MLNSNHIQQKIDYIGFNSELQKNIPYSFVDSEGKENGFINGSTKEGLFVSELPDVVLI
                     SKVYMDDSKPSFGYYSNNLKDVKVITKDNVNILTGYYLKDDIKISLSLTLQDEKTIKL
                     NSVHLDESGVAEILKFMNRKGNTNTSDSLMSFLESMNIKSIFVNFLQSNIKFILDANF
                     IISGTTSIGQFEFICDENDNIQPYFIKFNTLETNYTLYVGNRQNMIVEPNYDLDDSGD
                     ISSTVINFSQKYLYGIDSCVNKVVISPNIYTDEINITPVYETNNTYPEVIVLDANYIN
                     EKINVNINDLSIRYVWSNDGNDFILMSTSEENKVSQVKIRFVNVFKDKTLANKLSFNF
                     SDKQDVPVSEIILSFTPSYYEDGLIGYDLGLVSLYNEKFYINNFGMMVSGLIYINDSL
                     YYFKPPVNNLITGFVTVGDDKYYFNPINGGAASIGETIIDDKNYYFNQSGVLQTGVFS
                     TEDGFKYFAPANTLDENLEGEAIDFTGKLIIDENIYYFDDNYRGAVEWKELDGEMHYF
                     SPETGKAFKGLNQIGDYKYYFNSDGVMQKGFVSINDNKHYFDDSGVMKVGYTEIDGKH
                     FYFAENGEMQIGVFNTEDGFKYFAHHNEDLGNEEGEEISYSGILNFNNKIYYFDDSFT
                     AVVGWKDLEDGSKYYFDEDTAEAYIGLSLINDGQYYFNDDGIMQVGFVTINDKVFYFS
                     DSGIIESGVQNIDDNYFYIDDNGIVQIGVFDTSDGYKYFAPANTVNDNIYGQAVEYSG
                     LVRVGEDVYYFGETYTIETGWIYDMENESDKYYFNPETKKACKGINLIDDIKYYFDEK
                     GIMRTGLISFENNNYYFNENGEMQFGYINIEDKMFYFGEDGVMQIGVFNTPDGFKYFA
                     HQNTLDENFEGESINYTGWLDLDEKRYYFTDEYIAATGSVIIDGEEYYFDPDTAQLVI
                     SE"
     gene            8209..8709
                     /gene="tcdE"
                     /locus_tag="PC512_002455"
     CDS             8209..8709
                     /gene="tcdE"
                     /locus_tag="PC512_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin-like glycosylating toxin export protein
                     TcdE"
                     /protein_id="HDF2442192.1"
                     /translation="MHSSSPFYISNGNKIFFYINLGGVMNMTISFLSEHIFIKLVILT
                     ISFDTLLGCLSAIKSRKFNSSFGIDGGIRKVAMIACIFFLSVVDILTKFNFLFMLPQD
                     CINFLRLKHLGISEFFSILFILYESVSILKNMCLCGLPVPKRLKEKIAILLDAMTDEM
                     NAKDEK"
     gene            8788..8949
                     /locus_tag="PC512_002456"
     CDS             8788..8949
                     /locus_tag="PC512_002456"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442193.1"
                     /translation="MKLIMKTREQMPRDTQVLNTYNFEASVHYYIDDKVVYQTLVHKD
                     GAWSVGKIY"
     gene            9038..9220
                     /locus_tag="PC512_002457"
     CDS             9038..9220
                     /locus_tag="PC512_002457"
                     /inference="COORDINATES: protein motif:HMM:NF022413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442194.1"
                     /translation="MRDEGQNDIENKYQTLINDLIDSLKVIGKIYKEIKTLKKYKICL
                     QITIRQSPYLIEESIN"
     gene            9437..17569
                     /gene="tcdA"
                     /locus_tag="PC512_002458"
                     /gene_synonym="toxA"
     CDS             9437..17569
                     /gene="tcdA"
                     /locus_tag="PC512_002458"
                     /gene_synonym="toxA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_105161403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin TcdA"
                     /protein_id="HDF2442195.1"
                     /translation="MSLISKEELIKLAYSIRPRENEYKTILTNLDEYNKLTTNNNENK
                     YLQLKKLNESIDVFMNKYKTSSRNRALSNLKKDILKEVILIKNSNTSPVEKNLHFVWI
                     GGEVSDIALEYIKQWADINAEYNIKLWYDSEAFLVNTLKKAIVESSTTEALQLLEEEI
                     QNPQFDNMKFYKKRMEFIYDRQKRFINYYKSQINKPTVPTIDDIIKSHLVSEYNRDET
                     VLESYRTNSLRKINSNHGIDIRANSLFTEQELLNIYSQELLNRGNLAAASDIVRLLAL
                     KNFGGVYLDVDMLPGIHSDLFKTISRPSSIGLDRWEMIKLEAIMKYKKYINNYTSENF
                     DKLDQQLKDNFKLIIESKSEKSEIFSKLENLNVSDLEIKIAFALGSVINQALISKQGS
                     YLTNLVIEQVKNRYQFLNQHLNPAIESDNNFTDTTKIFHDSLFNSATAENSMFLTKIA
                     PYLQVGFMPEARSTISLSGPGAYASAYYDFINLQENTIEKTLKASDLIEFKFPENNLS
                     QLTEQEINSLWSFDQASAKYQFEKYVRDYTGGSLSEDNGVDFNKNTALDKNYLLNNKI
                     PSNNVEEAGSKNYVHYIIQLQGDDISYEATCNLFSKNPKNSIIIQRNMNESAKSYFLS
                     DDGESILELNKYRIPERLKNKEKVKVTFIGHGKDEFNTSEFARLSVDSLSNEISSFLD
                     TIKLDISPKNVEVNLLGCNMFSYDFNVEETYPGKLLLSIMDKITSTLPDVNKNSITIG
                     ANQYEVRINSEGRKELLAHSGKWINKEEAIMSDLSSKEYIFFDSIDNKLKAKSKNIPG
                     LASISEDIKTLLLDASVSPDTKFILNNLKLNIESSIGDYIYYEKLEPVKNIIHNSIDD
                     LIDEFNLLENVSDELYELKKLNNLDEKYLISFEDISKNNSTYSVRFINKSNGESVYVE
                     TEKEIFSKYSEHITKEISTIKNSIITDVNGNLLDNIQLDHTSQVNTLNAAFFIQSLID
                     YSSNKDVLNDLSTSVKVQLYAQLFSTGLNTIYDSIQLVNLISNAVNDTINVLPTITEG
                     IPIVSTILDGINLGAAIKELLDEHDPLLKKELEAKVGVLAINMSLSIAATVASIVGIG
                     AEVTIFLLPIAGISAGIPSLVNNELILHDKATSVVNYFNHLSESKKYGPLKTEDDKIL
                     VPIDDLVISEIDFNNNSIKLGTCNILAMEGGSGHTVTGNIDHFFSSPSISSHIPSLSI
                     YSAIGIETENLDFSKKIMMLPNAPSRVFWWETGAVPGLRSLENDGTRLLDSIRDLYPG
                     KFYWRFYAFFDYAITTLKPVYEDTNIKIKLDKDTRNFIMPTITTNEIRNKLSYSFDGA
                     GGTYSLLLSSYPISTNINLSKDDLWIFNIDNEVREISIENGTIKKGKLIKDVLSKIDI
                     NKNKLIIGNQTIDFSGDIDNKDRYIFLTCELDDKISLIIEINLVAKSYSLLLSGDKNY
                     LISNLSNTIEKINTLGLDSKNIAYNYTDESNNKYFGAISKTSQKSIIHYKKDSKNILE
                     FYNDSTLEFNSKDFIAEDINVFMKDDINTITGKYYVDNNTDKSIDFSISLVSKNQVKV
                     NGLYLNESVYSSYLDFVKNSDGHHNTSNFMNLFLDNISFWKLFGFENINFVIDKYFTL
                     VGKTNLGYVEFICDNNKNIDIYFGEWKTSSSKSTIFSGNGRNVVVEPIYNPDTGEDIS
                     TSLDFSYEPLYGIDRYINKVLIAPDLYTSLININTNYYSNEYYPEIIVLNPNTFHKKV
                     NINLDSSSFEYKWSTEGSDFILVRYLEESNKKILQKIRIKGILSNTQSFNKMSIDFKD
                     IKKLSLGYIMSNFKSFNSENELDRDHLGFKIIDNKTYYYDEDSKLVKGLININNSLFY
                     FDPIEFNLVTGWQTINGKKYYFDINTGAALTSYKIINGKHFYFNNDGVMQLGVFKGPD
                     GFEYFAPANTQNNNIEGQAIVYQSKFLTLNGKKYYFDNDSKAVTGWRIINNEKYYFNP
                     NNAIAAVGLQVIDNNKYYFNPDTAIISKGWQTVNGSRYYFDTDTAIAFNGYKTIDGKH
                     FYFDSDCVVKIGVFSTSNGFEYFAPANTYNNNIEGQAIVYQSKFLTLNGKKYYFDNNS
                     KAVTGWQTIDSKKYYFNTNTAEAATGWQTIDGKKYYFNTNTAEAATGWQTIDGKKYYF
                     NTNTAIASTGYTIINGKHFYFNTDGIMQIGVFKGPNGFEYFAPANTDANNIEGQAILY
                     QNEFLTLNGKKYYFGSDSKAVTGWRIINNKKYYFNPNNAIAAIHLCTINNDKYYFSYD
                     GILQNGYITIERNNFYFDANNESKMVTGVFKGPNGFEYFAPANTHNNNIEGQAIVYQN
                     KFLTLNGKKYYFDNDSKAVTGWQTIDGKKYYFNLNTAEAATGWQTIDGKKYYFNLNTA
                     EAATGWQTIDGKKYYFNTNTFIASTGYTSINGKHFYFNTDGIMQIGVFKGPNGFEYFA
                     PANTHNNNIEGQAILYQNKFLTLNGKKYYFGSDSKAVTGLRTIDGKKYYFNTNTAVAV
                     TGWQTINGKKYYFNTNTSIASTGYTIISGKHFYFNTDGIMQIGVFKGPDGFEYFAPAN
                     TDANNIEGQAIRYQNRFLYLHDNIYYFGNNSKAATGWVTIDGNRYYFEPNTAMGANGY
                     KTIDNKNFYFRNGLPQIGVFKGSNGFEYFAPANTDANNIEGQAIRYQNRFLHLLGKIY
                     YFGNNSKAVTGWQTINGKVYYFMPDTAMAAAGGLFEIDGVIYFFGVDGVKAPGIYG"
     gene            complement(17904..18602)
                     /gene="tcdC"
                     /locus_tag="PC512_002459"
     CDS             complement(17904..18602)
                     /gene="tcdC"
                     /locus_tag="PC512_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin anti-sigma factor TcdC"
                     /protein_id="HDF2442196.1"
                     /translation="MFSKKNDGNEFSNEGKGSSKKIIKFFKSTKGIALLAFILGVFFG
                     NISSPACSEDHEEVISNQTSVIDSQKTEIETLNSKLSDAEPWFKMKDDEKKAIEAENQ
                     RKAEEAKKAEEAKKAEEQRKKEEEEKKGYDTGITYDQLARTPDDYKYKKVKFEGKVIQ
                     VIEDGDEVQIRLAVSGNYDKVVLCSYKKSITPSRVLEDDYITIRGISAGTITYESTMG
                     GNITIPGIAVEKIN"
     gene            19028..19273
                     /locus_tag="PC512_002460"
     CDS             19028..19273
                     /locus_tag="PC512_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pathogenicity locus"
                     /protein_id="HDF2442197.1"
                     /translation="MGELQKIPGVGKATEKSLIMLGYTTIKSLKDANPAQMYEKECLI
                     RGQHIDRCQLYVYRCAVYFASTENPEPEKLKWWYWKD"
     gene            complement(19491..19760)
                     /locus_tag="PC512_002461"
     CDS             complement(19491..19760)
                     /locus_tag="PC512_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HDF2442198.1"
                     /translation="MFESRCGVCCDSCTKKEQVNCTGCPTMEKPFWGGECKVKTCCES
                     KELNHCGECDTFPCDMLLNKGKDQGFDPMVNIEQCRKWLEETVSN"
     gene            complement(20638..21375)
                     /locus_tag="PC512_002462"
     CDS             complement(20638..21375)
                     /locus_tag="PC512_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2442199.1"
                     /translation="MLRKSVLGEILKLKNSFIWYVLLALPLISVLIGSGNFYLNQGIL
                     KKEWYSLWTQVSLFYGEFFFPILIAIFCAYICRLEHMNHNWNNVMTLPVNLKNIFLSK
                     LTVVSILTAITQVFFVIFYIVAGNMFGFSGSVPKELTGWIAKGWIISISIASIQLYMS
                     IKIRSFATPIGISLCLSLFGMGLIVAKPAVGIFFPYSMLGSAMGVIKQSALNVNDTIV
                     TICVAFITTIVFSEIANRNFRKNDVIS"
     gene            complement(21387..22148)
                     /locus_tag="PC512_002463"
     CDS             complement(21387..22148)
                     /locus_tag="PC512_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2442200.1"
                     /translation="MKYLGLEFYKLKRKKIILMTFLFVAVEIMWCIINSNRAITRNPD
                     MLGGFEYSYMFMSFASLNGLFFPILISIITSRISDIEHKGDTWKLLKSSVTSLNSIYL
                     SKFLCSAILVSIPVLMQVLSIVLFGHFRGVIESISVSLLLKYTLGTILVSIAIIALHL
                     WIATVIPNQMIAITFGMIGSFIGLTSGLFYQGIRRLFIWSYYLELSPLSYAYDNVLGS
                     SVYRIDMNFSITILVFLIGMLIYYIGRNHLLKKEV"
     gene            complement(22148..23062)
                     /locus_tag="PC512_002464"
     CDS             complement(22148..23062)
                     /locus_tag="PC512_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2442201.1"
                     /translation="MEMIIRTQRLSKEYNKIFRVKDIDLRVPQGAVYGFLGPNGAGKS
                     TTLKMLLGLAKPTQGNINILGKELNEKNRISILKDIGSLIESPSYYGHLTGLENMTIM
                     QKLLDLPKKNVNEALKIVRLENQKNKKVSQYSLGMKQRLGIAMAIMKFPKLLILDEPT
                     NGLDPAGIEEIRELIKSLPEKYGMTVLISSHLLSEIDQIATSIGIINHGELVFQDSIK
                     ELHNRGQSQIAIKTKNVVSAQKLLNTKGYMSLIQDGYLTIENLKDSDVAKINGMLVHS
                     NIDVFRIEEHKKSLEDIFLELTGKAVTL"
     gene            23233..23940
                     /locus_tag="PC512_002465"
     CDS             23233..23940
                     /locus_tag="PC512_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2442202.1"
                     /translation="MESIKDKKILVVDDHKELLKMIDEILRKEGFSRVFLASSYEEAV
                     RVFRNVKPDCAILDVVLPDGDGFSIMRKIRETSKIPVIFLSARGEDEDRLIGLGLGAD
                     DYIVKPFLPKELTLRLVGILNRVYVPIEEEELPVFKLGDSVVVNLNSACVEKDGQEIS
                     LTAKEHSLLLKLYENKGRIVTNDSLCQAIWGDDMYGYENTLMVHVRRVREKIEKTPST
                     PKHLITVRGLGYKLMIN"
     gene            23985..25391
                     /locus_tag="PC512_002466"
     CDS             23985..25391
                     /locus_tag="PC512_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2442203.1"
                     /translation="MDSVKYILRRFIGSSILISLLFIVLNIAGFLLFSYMLFVSKYSD
                     NLDTSDSREIKSNLIMIEDNLILRNGKFILDDSSKEVLHKNKVWAMLIDNNGDRIWGF
                     DLPKEIPSHYTLTDVAKFSRFFLKDYPVYVWEHPNGILVTGYPKDKYTKFNLTYTVKE
                     IEQFPMLIIGMFLVNAIVTFLIALFIGLKMVKSIKPIITGIKLMSKGEPVLLQEKGIL
                     SDISKSINTVSKELQMKDEKLRKKEEARSNWIAGISHDIRTPLSMIIGYAGELEESSS
                     LSNREQEQVSIICNQGIKIRELVNDLNLVSKLEYNMQALNCDKIRVSAFLRELISEFI
                     NNNLDNDFYVEFDILNEDIIIDADKKLLKRAISNLIQNSITHNQQGCNIRVTSKSDLD
                     FCYIIVEDDGKGMSQERINSLLKSQNGLSEAYAKGQNHGLGILIVSGIINAHRGKLDI
                     TSIDSQGLKTILKLPLIK"
BASE COUNT        10135 a         2999 c         3927 g         8868 t
ORIGIN      
        1 tcatataaaa tttaatttat ttgccgatta tataattata atgactgatt taattccgat
       61 gttgtcaaaa ttttcaaata aatcatcatt ataaatataa gagaggatga ttttatgcaa
      121 aagtcttttt atgaattaat tgttttagca agaaataact cagtagatga tttgcaagaa
      181 attttattta tgtttaagcc attagtaaaa aagcttagta gagttttaca ttatgaagag
      241 ggagaaacag atttaataat attttttatt gaattaataa aaaatattaa attaagtagc
      301 ttttcagaaa aaagcgatgc tattatagtc aaatatattc ataaatcatt actgaataag
      361 acttttgagt tgtctagaag atattctaaa atgaagttta attttgtaga atttgatgaa
      421 aatatcttaa atatgaaaaa taattatcaa agtaagtcta tttttgagga agatatttgt
      481 tttttcggat atattttgaa agaattatct ggtattcaaa gaaaagttat tttttataaa
      541 tatttaaaag gatattctga tagagaaata tcagtgaaat taaaaatatc tagacaagct
      601 gttaataagg ctaaaaatag agcatttaaa aaaataaaaa aagactatga aaattatttt
      661 aacttgtaat taatgagctt aaagaaatat ttacaataga aatcaaattt tagaattaac
      721 tttattgtaa aatcaataac ttaatctaag aatatcttaa tttttatatt ttatatagaa
      781 caaagtttac atatttattt cagacaacgt ctttattcaa tcgaagagca aattaatcaa
      841 ctgagtgtct tcaatttaaa atgttaggaa gtgaatgtat atgaaaacct aagtagatat
      901 tagtatattt tataaataga aaggaggata tataaaagag ttttatcatt tagatgtaaa
      961 aatattatag taaaggagaa aattttatga gtttagttaa tagaaaacag ttagaaaaaa
     1021 tggcaaatgt aagatttcgt actcaagaag atgaatatgt tgcaatattg gatgctttag
     1081 aagaatatca taatatgtca gagaatactg tagtcgaaaa atatttaaaa ttaaaagata
     1141 taaatagttt aacagatatt tatatagata catataaaaa atctggtaga aataaagcct
     1201 taaaaaaatt taaggaatat ctagttacag aagtattaga gctaaagaat aataatttaa
     1261 ctccagttga gaaaaattta cattttgttt ggattggagg tcaaataaat gacactgcta
     1321 ttaattatat aaatcaatgg aaagatgtaa atagtgatta taatgttaat gttttttatg
     1381 atagtaatgc atttttgata aacacattga aaaaaactgt agtagaatca gcaataaatg
     1441 atacacttga atcatttaga gaaaacttaa atgaccctag atttgactat aataaattct
     1501 tcagaaaacg tatggaaata atttatgata aacagaaaaa tttcataaac tactataaag
     1561 ctcaaagaga agaaaatcct gaacttataa ttgatgatat tgtaaagaca tatctttcaa
     1621 atgagtattc aaaggagata gatgaactta atacctatat tgaagaatcc ttaaataaaa
     1681 ttacacagaa tagtggaaat gatgttagaa actttgaaga atttaaaaat ggagagtcat
     1741 tcaacttata tgaacaagag ttggtagaaa ggtggaattt agctgctgct tctgacatat
     1801 taagaatatc tgcattaaaa gaaattggtg gtatgtattt agatgttgat atgttaccag
     1861 gaatacaacc agacttattt gagtctatag agaaacctag ttcagtaaca gtggattttt
     1921 gggaaatgac aaagttagaa gctataatga aatacaaaga atatatacca gaatatacct
     1981 cagaacattt tgacatgtta gacgaagaag ttcaaagtag ttttgaatct gttctagctt
     2041 ctaagtcaga taaatcagaa atattctcat cacttggtga tatggaggca tcaccactag
     2101 aagttaaaat tgcatttaat agtaagggta ttataaatca agggctaatt tctgtgaaag
     2161 actcatattg tagcaattta atagtaaaac aaatcgagaa tagatataaa atattgaata
     2221 atagtttaaa tccagctatt agcgaggata atgattttaa tactacaacg aataccttta
     2281 ttgatagtat aatggctgaa gctaatgcag ataatggtag atttatgatg gaactaggaa
     2341 agtatttaag agttggtttc ttcccagatg ttaaaactac tattaactta agtggccctg
     2401 aagcatatgc ggcagcttat caagatttat taatgtttaa agaaggcagt atgaatatcc
     2461 atttgataga agctgattta agaaactttg aaatctctaa aactaatatt tctcaatcaa
     2521 ctgaacaaga aatggctagc ttatggtcat ttgacgatgc aagagctaaa gctcaatttg
     2581 aagaatataa aaggaattat tttgaaggtt ctcttggtga agatgataat cttgattttt
     2641 ctcaaaatat agtagttgac aaggagtatc ttttagaaaa aatatcttca ttagcaagaa
     2701 gttcagagag aggatatata cactatattg ttcagttaca aggagataaa attagttatg
     2761 aagcagcatg taacttattt gcaaagactc cttatgatag tgtactattt cagaaaaata
     2821 tagaagattc agaaattgca tattattata atcctggaga tggtgaaata caagaaatag
     2881 acaagtataa aattccaagt ataatttctg atagacctaa gattaaatta acatttattg
     2941 gtcatggtaa agatgaattt aatactgata tatttgcagg ttttgatgta gattcattat
     3001 ccacagaaat agaagcagca atagatttag ctaaagagga tatttctcct aagtcaatag
     3061 aaataaattt attaggatgt aatatgttta gctactctat caacgtagag gagacttatc
     3121 ctggaaaatt attacttaaa gttaaagata aaatatcaga attaatgcca tctataagtc
     3181 aagactctat tatagtaagt gcaaatcaat atgaagttag aataaatagt gaaggaagaa
     3241 gagaattatt ggatcattct ggtgaatgga taaataaaga agaaagtatt ataaaggata
     3301 tttcatcaaa agaatatata tcatttaatc ctaaagaaaa taaaattaca gtaaaatcta
     3361 aaaatttacc tgagctatct acattattac aagaaattag aaataattct aattcaagtg
     3421 atattgaact agaagaaaaa gtaatgttaa cagaatgtga gataaatgtt atttcaaata
     3481 tagatacgca aattgttgag gaaaggattg aagaagctaa gaatttaact tctgactcta
     3541 ttaattatat aaaagatgaa tttaaactaa tagaatctat ttctgatgca ctatgtgact
     3601 taaaacaaca gaatgaatta gaagattctc attttatatc ttttgaggac atatcagaga
     3661 ctgatgaggg atttagtata agatttatta ataaagaaac tggagaatct atatttgtag
     3721 aaactgaaaa aacaatattc tctgaatatg ctaatcatat aactgaagag atttctaaga
     3781 taaaaggtac tatatttgat actgtaaatg gtaagttagt aaaaaaagta aatttagata
     3841 ctacacacga agtaaatact ttaaatgctg cattttttat acaatcatta atagaatata
     3901 atagttctaa agaatctctt agtaatttaa gtgtagcaat gaaagtccaa gtttacgctc
     3961 aattatttag tactggttta aatactatta cagatgcagc caaagttgtt gaattagtat
     4021 caactgcatt agatgaaact atagacttac ttcctacatt atctgaagga ttacctataa
     4081 ttgcaactat tatagatggt gtaagtttag gtgcagcaat caaagagcta agtgaaacga
     4141 gtgacccatt attaagacaa gaaatagaag ctaagatagg tataatggca gtaaatttaa
     4201 caacagctac aactgcaatc attacttcat ctttgggggt agctagtgga tttagtatac
     4261 ttttagttcc tttagcagga atttcagcag gtataccaag cttagtaaac aatgaacttg
     4321 tacttcgaga taaggcaaca aaggttgtag attattttaa acatgtttca ttagttgaaa
     4381 ctgaaggagt atttacttta ttagatgata aaataatgat gccacaagat gatttagtga
     4441 tatcagaaat agattttaat aataattcaa tagttttagg taaatgtgaa atctggagaa
     4501 tggaaggtgg ttcaggtcat actgtaactg atgatataga tcacttcttt tcagcaccat
     4561 caataacata tagagagcca cacttatcta tatatgacgt attggaagta caaaaagaag
     4621 aacttgattt gtcaaaagat ttaatggtat tacctaatgc tccaaataga gtatttgctt
     4681 gggaaacagg atggacacca ggtttaagaa gcttagaaaa tgatggcaca aaactgttag
     4741 accgtataag agataactat gaaggtgagt tttattggag atattttgct tttatagctg
     4801 atgctttaat aacaacatta aaaccaagat atgaagatac taatataaga ataaatttag
     4861 atagtaatac tagaagtttt atagttccaa taataactac agaatatata agagaaaaat
     4921 tatcatattc tttctatggt tcaggaggaa cttatgcatt gtctctttct caatataata
     4981 tgggtataaa tatagaatta agtgaaagtg atgtttggat tatagatgtt gataatgttg
     5041 tgagagatgt aactatagaa tctgataaaa ttaaaaaagg tgatttaata gaaggtattt
     5101 tatctacact aagtattgaa gagaataaaa ttatcttaaa tagccatgag attaattttt
     5161 ctggtgaggt aaatggaagt aatggatttg tttctttaac attttcaatt ttagaaggaa
     5221 taaatgcaat tatagaagtt gatttattat ctaaatcata taaattactt atttctggcg
     5281 aattaaaaat attgatgtta aattcaaatc atattcaaca gaaaatagat tatataggat
     5341 tcaatagcga attacagaaa aatataccat atagctttgt agatagtgaa ggaaaagaga
     5401 atggttttat taatggttca acaaaagaag gtttatttgt atctgaatta cctgatgtag
     5461 ttcttataag taaggtttat atggatgata gtaagccttc atttggatat tatagtaata
     5521 atttgaaaga tgtcaaagtt ataactaaag ataatgttaa tatattaaca ggttattatc
     5581 ttaaggatga tataaaaatc tctctttctt tgactctaca agatgaaaaa actataaagt
     5641 taaatagtgt gcatttagat gaaagtggag tagctgagat tttgaagttc atgaatagaa
     5701 aaggtaatac aaatacttca gattctttaa tgagcttttt agaaagtatg aatataaaaa
     5761 gtattttcgt taatttctta caatctaata ttaagtttat attagatgct aattttataa
     5821 taagtggtac tacttctatt ggccaatttg agtttatttg tgatgaaaat gataatatac
     5881 aaccatattt cattaagttt aatacactag aaactaatta tactttatat gtaggaaata
     5941 gacaaaatat gatagtggaa ccaaattatg atttagatga ttctggagat atatcttcaa
     6001 ctgttatcaa tttctctcaa aagtatcttt atggaataga cagttgtgtt aataaagttg
     6061 taatttcacc aaatatttat acagatgaaa taaatataac gcctgtatat gaaacaaata
     6121 atacttatcc agaagttatt gtattagatg caaattatat aaatgaaaaa ataaatgtta
     6181 atatcaatga tctatctata cgatatgtat ggagtaatga tggtaatgat tttattctta
     6241 tgtcaactag tgaagaaaat aaggtgtcac aagttaaaat aagattcgtt aatgttttta
     6301 aagataagac tttggcaaat aagctatctt ttaactttag tgataaacaa gatgtacctg
     6361 taagtgaaat aatcttatca tttacacctt catattatga ggatggattg attggctatg
     6421 atttgggtct agtttcttta tataatgaga aattttatat taataacttt ggaatgatgg
     6481 tatctggatt aatatatatt aatgattcat tatattattt taaaccacca gtaaataatt
     6541 tgataactgg atttgtgact gtaggcgatg ataaatacta ctttaatcca attaatggtg
     6601 gagctgcttc aattggagag acaataattg atgacaaaaa ttattatttc aaccaaagtg
     6661 gagtgttaca aacaggtgta tttagtacag aagatggatt taaatatttt gccccagcta
     6721 atacacttga tgaaaaccta gaaggagaag caattgattt tactggaaaa ttaattattg
     6781 acgaaaatat ttattatttt gatgataatt atagaggagc tgtagaatgg aaagaattag
     6841 atggtgaaat gcactatttt agcccagaaa caggtaaagc ttttaaaggt ctaaatcaaa
     6901 taggtgatta taaatactat ttcaattctg atggagttat gcaaaaagga tttgttagta
     6961 taaatgataa taaacactat tttgatgatt ctggtgttat gaaagtaggt tacactgaaa
     7021 tagatggcaa gcatttctac tttgctgaaa acggagaaat gcaaatagga gtatttaata
     7081 cagaagatgg atttaaatat tttgctcatc ataatgaaga tttaggaaat gaagaaggtg
     7141 aagaaatctc atattctggt atattaaatt tcaataataa aatttactat tttgatgatt
     7201 catttacagc tgtagttgga tggaaagatt tagaggatgg ttcaaagtat tattttgatg
     7261 aagatacagc agaagcatat ataggtttgt cattaataaa tgatggtcaa tattatttta
     7321 atgatgatgg aattatgcaa gttggatttg tcactataaa tgataaagtc ttctacttct
     7381 ctgactctgg aattatagaa tctggagtac aaaacataga tgacaattat ttctatatag
     7441 atgataatgg tatagttcaa attggtgtat ttgatacttc agatggatat aaatattttg
     7501 cacctgctaa tactgtaaat gataatattt acggacaagc agttgaatat agtggtttag
     7561 ttagagttgg ggaagatgta tattattttg gagaaacata tacaattgag actggatgga
     7621 tatatgatat ggaaaatgaa agtgataaat attatttcaa tccagaaact aaaaaagcat
     7681 gcaaaggtat taatttaatt gatgatataa aatattattt tgatgagaag ggcataatga
     7741 gaacgggtct tatatcattt gaaaataata attattactt taatgagaat ggtgaaatgc
     7801 aatttggtta tataaatata gaagataaga tgttctattt tggtgaagat ggtgtcatgc
     7861 agattggagt atttaataca ccagatggat ttaaatactt tgcacatcaa aatactttgg
     7921 atgagaattt tgagggagaa tcaataaact atactggttg gttagattta gatgaaaaga
     7981 gatattattt tacagatgaa tatattgcag caactggttc agttattatt gatggtgagg
     8041 agtattattt tgatcctgat acagctcaat tagtgattag tgaatagata aaaatatgtt
     8101 aaatatatcc tcttatactt aaatatataa aaataaacaa aatgatacac tacataaagt
     8161 gttctatcta atatgaagat ttaccaataa aaaggtggac tatgatgaat gcacagtagt
     8221 tcaccttttt atatttctaa tggtaacaaa atattttttt atataaacct aggaggcgtt
     8281 atgaatatga caatatcttt tttatcagag catatattta taaagttagt aattttaact
     8341 atatcatttg atacattatt aggatgttta agtgcaataa aaagtcgtaa atttaattct
     8401 agttttggaa tagatggagg aatcagaaaa gtagcaatga tagcatgtat atttttttta
     8461 tcagtagttg acattcttac aaagtttaac tttttattta tgttaccaca agattgtatc
     8521 aattttttaa gactaaaaca tcttggaata tctgaatttt tctctatttt atttatttta
     8581 tatgaaagtg taagtatatt aaaaaatatg tgcttatgtg gattaccagt acctaagaga
     8641 ttaaaggaaa aaatagcaat tttactagat gcaatgacag atgaaatgaa tgctaaggat
     8701 gaaaagtaag taatggtaga tataataaag atattaacaa ataaaaagtg ttatccaaat
     8761 aagaatagct gaaagttatc ataattcatg aaactaataa tgaaaacgag ggagcagatg
     8821 ccaagagaca cacaagtatt aaatacatat aatttcgaag caagtgttca ttactatata
     8881 gatgacaagg tagtatatca aacattggtt cacaaagatg gtgcatggtc agttggtaaa
     8941 atctattaag ctacattagt tacagatatc acaaactata atagttaaac atagaaatat
     9001 gtgtaaattg tgatggaaat tattcaaaaa cacaaaaata cgtgatgaag gacaaaatga
     9061 tatagaaaat aagtatcaaa ccttaataaa tgatttaatt gatagtttaa aagttatagg
     9121 aaaaatatat aaagaaataa aaacattaaa aaaatataag atatgtttac aaattactat
     9181 cagacaatct ccttatctaa tagaagagtc aattaactaa ttgagtatct ttaaattgaa
     9241 atgttaggaa gtgatttaaa tatgaaaact taaattataa aaaatcaata ttaatttatt
     9301 tttaaaaaat agaaaggagt gtataagatt tattttcaaa gtttaaaaac aagaaaatca
     9361 atttaaattt cagaaggaat aaatgtggtt atagaagtgg atttattatc aaaaataata
     9421 atactaggag gtttttatgt ctttaatatc taaagaagag ttaataaaac tcgcatatag
     9481 cattagacca agagaaaatg agtataaaac tatactaact aatttagacg aatataataa
     9541 gttaactaca aacaataatg aaaataaata tttacaatta aaaaaactaa atgaatcaat
     9601 tgatgttttt atgaataaat ataaaacttc aagcagaaat agagcactct ctaatctaaa
     9661 aaaagatata ttaaaagaag taattcttat taaaaattcc aatacaagcc ctgtagaaaa
     9721 aaatttacat tttgtatgga taggtggaga agtcagtgat attgctcttg aatacataaa
     9781 acaatgggct gatattaatg cagaatataa tattaaactg tggtatgata gtgaagcatt
     9841 cttagtaaat acactaaaaa aggctatagt tgaatcttct accactgaag cattacagct
     9901 actagaggaa gagattcaaa atcctcaatt tgataatatg aaattttaca aaaaaaggat
     9961 ggaatttata tatgatagac aaaaaaggtt tataaattat tataaatctc aaatcaataa
    10021 acctacagta cctacaatag atgatattat aaagtctcat ctagtatctg aatataatag
    10081 agatgaaact gtattagaat catatagaac aaattctttg agaaaaataa atagtaatca
    10141 tggtatagat atcagggcta atagtttgtt tacagaacaa gagttattaa atatttatag
    10201 tcaggagttg ttaaatcgtg gaaatttagc tgcagcatct gacatagtaa gattattagc
    10261 cctaaaaaat tttggcggag tatatttaga tgttgatatg cttccaggta ttcactctga
    10321 tttatttaaa acaatatcta gacctagctc tattggacta gaccgttggg aaatgataaa
    10381 attagaggct attatgaagt ataaaaaata tataaataat tatacatcag aaaactttga
    10441 taaacttgat caacaattaa aagataattt taaactcatt atagaaagta aaagtgaaaa
    10501 atctgagata ttttctaaat tagaaaattt aaatgtatct gatcttgaaa ttaaaatagc
    10561 tttcgcttta ggcagtgtta taaatcaagc cttgatatca aaacaaggtt catatcttac
    10621 taacctagta atagaacaag taaaaaatag atatcaattt ttaaaccaac accttaaccc
    10681 agccatagag tctgataata acttcacaga tactactaaa atttttcatg attcattatt
    10741 taattcagct accgcagaaa actctatgtt tttaacaaaa atagcaccat acttacaagt
    10801 aggttttatg ccagaagctc gctccacaat aagtttaagt ggtccaggag cttatgcgtc
    10861 agcttactat gatttcataa atttacaaga aaatactata gaaaaaactt taaaagcatc
    10921 agatttaata gaatttaaat tcccagaaaa taatctatct caattgacag aacaagaaat
    10981 aaatagtcta tggagctttg atcaagcaag tgcaaaatat caatttgaga aatatgtaag
    11041 agattatact ggtggatctc tttctgaaga caatggggta gactttaata aaaatactgc
    11101 cctcgacaaa aactatttat taaataataa aattccatca aacaatgtag aagaagctgg
    11161 aagtaaaaat tatgttcatt atatcataca gttacaagga gatgatataa gttatgaagc
    11221 aacatgcaat ttattttcta aaaatcctaa aaatagtatt attatacaac gaaatatgaa
    11281 tgaaagtgca aaaagctact ttttaagtga tgatggagaa tctattttag aattaaataa
    11341 atataggata cctgaaagat taaaaaataa ggaaaaagta aaagtaacct ttattggaca
    11401 tggtaaagat gaattcaaca caagcgaatt tgctagatta agtgtagatt cactttccaa
    11461 tgagataagt tcatttttag ataccataaa attagatata tcacctaaaa atgtagaagt
    11521 aaacttactt ggatgtaata tgtttagtta tgattttaat gttgaagaaa cttatcctgg
    11581 gaagttgcta ttaagtatta tggacaaaat tacttccact ttacctgatg taaataaaaa
    11641 ttctattact ataggagcaa atcaatatga agtaagaatt aatagtgagg gaagaaaaga
    11701 acttctggct cactcaggta aatggataaa taaagaagaa gctattatga gcgatttatc
    11761 tagtaaagaa tacatttttt ttgattctat agataataag ctaaaagcaa agtccaagaa
    11821 tattccagga ttagcatcaa tatcagaaga tataaaaaca ttattacttg atgcaagtgt
    11881 tagtcctgat acaaaattta ttttaaataa tcttaagctt aatattgaat cttctattgg
    11941 tgattacatt tattatgaaa aattagagcc tgttaaaaat ataattcaca attctataga
    12001 tgatttaata gatgagttca atctacttga aaatgtatct gatgaattat atgaattaaa
    12061 aaaattaaat aatctagatg agaagtattt aatatctttt gaagatatct caaaaaataa
    12121 ttcaacttac tctgtaagat ttattaacaa aagtaatggt gagtcagttt atgtagaaac
    12181 agaaaaagaa attttttcaa aatatagcga acatattaca aaagaaataa gtactataaa
    12241 gaatagtata attacagatg ttaatggtaa tttattggat aatatacagt tagatcatac
    12301 ttctcaagtt aatacattaa acgcagcatt ctttattcaa tcattaatag attatagtag
    12361 caataaagat gtactgaatg atttaagtac ctcagttaag gttcaacttt atgctcaact
    12421 atttagtaca ggtttaaata ctatatatga ctctatccaa ttagtaaatt taatatcaaa
    12481 tgcagtaaat gatactataa atgtactacc tacaataaca gaggggatac ctattgtatc
    12541 tactatatta gacggaataa acttaggtgc agcaattaag gaattactag acgaacatga
    12601 cccattacta aaaaaagaat tagaagctaa ggtgggtgtt ttagcaataa atatgtcatt
    12661 atctatagct gcaactgtag cttcaattgt tggaataggt gctgaagtta ctattttctt
    12721 attacctata gctggtatat ctgcaggaat accttcatta gttaataatg aattaatatt
    12781 gcatgataag gcaacttcag tggtaaacta ttttaatcat ttgtctgaat ctaaaaaata
    12841 tggccctctt aaaacagaag atgataaaat tttagttcct attgatgatt tagtaatatc
    12901 agaaatagat tttaataata attcgataaa actaggaaca tgtaatatat tagcaatgga
    12961 ggggggatca ggacacacag tgactggtaa tatagatcac tttttctcat ctccatctat
    13021 aagttctcat attccttcat tatcaattta ttctgcaata ggtatagaaa cagaaaatct
    13081 agatttttca aaaaaaataa tgatgttacc taatgctcct tcaagagtgt tttggtggga
    13141 aactggagca gttccaggtt taagatcatt ggaaaatgac ggaactagat tacttgattc
    13201 aataagagat ttatacccag gtaaatttta ctggagattc tatgcttttt tcgattatgc
    13261 aataactaca ttaaaaccag tttatgaaga cactaatatt aaaattaaac tagataaaga
    13321 tactagaaac ttcataatgc caactataac tactaacgaa attagaaaca aattatctta
    13381 ttcatttgat ggagcaggag gaacttactc tttattatta tcttcatatc caatatcaac
    13441 gaatataaat ttatctaaag atgatttatg gatatttaat attgataatg aagtaagaga
    13501 aatatctata gaaaatggta ctattaaaaa aggaaagtta ataaaagatg ttttaagtaa
    13561 aattgatata aataaaaata aacttattat aggcaatcaa acaatagatt tttcaggcga
    13621 tatagataat aaagatagat atatattctt gacttgtgag ttagatgata aaattagttt
    13681 aataatagaa ataaatcttg ttgcaaaatc ttatagtttg ttattgtctg gggataaaaa
    13741 ttatttgata tccaatttat ctaatactat tgagaaaatc aatactttag gcctagatag
    13801 taaaaatata gcgtacaatt acactgatga atctaataat aaatattttg gagctatatc
    13861 taaaacaagt caaaaaagca taatacatta taaaaaagac agtaaaaata tattagaatt
    13921 ttataatgac agtacattag aatttaacag taaagatttt attgctgaag atataaatgt
    13981 atttatgaaa gatgatatta atactataac aggaaaatac tatgttgata ataatactga
    14041 taaaagtata gatttctcta tttctttagt tagtaaaaat caagtaaaag taaatggatt
    14101 atatttaaat gaatccgtat actcatctta ccttgatttt gtgaaaaatt cagatggaca
    14161 ccataatact tctaatttta tgaatttatt tttggacaat ataagtttct ggaaattgtt
    14221 tgggtttgaa aatataaatt ttgtaatcga taaatacttt acccttgttg gtaaaactaa
    14281 tcttggatat gtagaattta tttgtgacaa taataaaaat atagatatat attttggtga
    14341 atggaaaaca tcgtcatcta aaagcactat atttagcgga aatggtagaa atgttgtagt
    14401 agagcctata tataatcctg atacgggtga agatatatct acttcactag atttttccta
    14461 tgaacctctc tatggaatag atagatatat caataaagta ttgatagcac ctgatttata
    14521 tacaagttta ataaatatta ataccaatta ttattcaaat gagtactacc ctgagattat
    14581 agttcttaac ccaaatacat tccacaaaaa agtaaatata aatttagata gttcttcttt
    14641 tgagtataaa tggtctacag aaggaagtga ctttatttta gttagatact tagaagaaag
    14701 taataaaaaa atattacaaa aaataagaat caaaggtatc ttatctaata ctcaatcatt
    14761 taataaaatg agtatagatt ttaaagatat taaaaaacta tcattaggat atataatgag
    14821 taattttaaa tcatttaatt ctgaaaatga attagataga gatcatttag gatttaaaat
    14881 aatagataat aaaacttatt actatgatga agatagtaaa ttagttaaag gattaatcaa
    14941 tataaataat tcattattct attttgatcc tatagaattt aacttagtaa ctggatggca
    15001 aactatcaat ggtaaaaaat attattttga tataaatact ggagcagctt taactagtta
    15061 taaaattatt aatggtaaac acttttattt taataatgat ggtgtgatgc agttgggagt
    15121 atttaaagga cctgatggat ttgaatattt tgcacctgcc aatactcaaa ataataacat
    15181 agaaggtcag gctatagttt atcaaagtaa attcttaact ttgaatggca aaaaatatta
    15241 ttttgataat gactcaaaag cagtcactgg atggagaatt attaacaatg agaaatatta
    15301 ctttaatcct aataatgcta ttgctgcagt cggattgcaa gtaattgaca ataataagta
    15361 ttatttcaat cctgacactg ctatcatctc aaaaggttgg cagactgtta atggtagtag
    15421 atactacttt gatactgata ccgctattgc ctttaatggt tataaaacta ttgatggtaa
    15481 acacttttat tttgatagtg attgtgtagt gaaaataggt gtgtttagta cctctaatgg
    15541 atttgaatat tttgcacctg ctaatactta taataataac atagaaggtc aggctatagt
    15601 ttatcaaagt aaattcttaa ctttgaatgg taaaaaatat tactttgata ataactcaaa
    15661 agcagttacc ggatggcaaa ctattgatag taaaaaatat tactttaata ctaacactgc
    15721 tgaagcagct actggatggc aaactattga tggtaaaaaa tattacttta atactaacac
    15781 tgctgaagca gctactggat ggcaaactat tgatggtaaa aaatattact ttaatactaa
    15841 cactgctata gcttcaactg gttatacaat tattaatggt aaacattttt attttaatac
    15901 tgatggtatt atgcagatag gagtgtttaa aggacctaat ggatttgaat attttgcacc
    15961 tgctaatacg gatgctaaca acatagaagg tcaagctata ctttaccaaa atgaattctt
    16021 aactttgaat ggtaaaaaat attactttgg tagtgactca aaagcagtta ctggatggag
    16081 aattattaac aataagaaat attactttaa tcctaataat gctattgctg caattcatct
    16141 atgcactata aataatgaca agtattactt tagttatgat ggaattcttc aaaatggata
    16201 tattactatt gaaagaaata atttctattt tgatgctaat aatgaatcta aaatggtaac
    16261 aggagtattt aaaggaccta atggatttga gtattttgca cctgctaata ctcacaataa
    16321 taacatagaa ggtcaggcta tagtttacca gaacaaattc ttaactttga atggcaaaaa
    16381 atattatttt gataatgact caaaagcagt tactggatgg caaaccattg atggtaaaaa
    16441 atattacttt aatcttaaca ctgctgaagc agctactgga tggcaaacta ttgatggtaa
    16501 aaaatattac tttaatctta acactgctga agcagctact ggatggcaaa ctattgatgg
    16561 taaaaaatat tactttaata ctaacacttt catagcctca actggttata caagtattaa
    16621 tggtaaacat ttttatttta atactgatgg tattatgcag ataggagtgt ttaaaggacc
    16681 taatggattt gaatactttg cacctgctaa tactcataat aataacatag aaggtcaagc
    16741 tatactttac caaaataaat tcttaacttt gaatggtaaa aaatattact ttggtagtga
    16801 ctcaaaagca gttaccggat tgcgaactat tgatggtaaa aaatattact ttaatactaa
    16861 cactgctgtt gcagttactg gatggcaaac tattaatggt aaaaaatact actttaatac
    16921 taacacttct atagcttcaa ctggttatac aattattagt ggtaaacatt tttattttaa
    16981 tactgatggt attatgcaga taggagtgtt taaaggacct gatggatttg aatactttgc
    17041 acctgctaat acagatgcta acaatataga aggtcaagct atacgttatc aaaatagatt
    17101 cctatattta catgacaata tatattattt tggtaataat tcaaaagcgg ctactggttg
    17161 ggtaactatt gatggtaata gatattactt cgagcctaat acagctatgg gtgcgaatgg
    17221 ttataaaact attgataata aaaattttta ctttagaaat ggtttacctc agataggggt
    17281 gtttaaaggg tctaatggat ttgaatactt tgcacctgct aatacggatg ctaacaatat
    17341 agaaggtcaa gctatacgtt atcaaaatag attcctacat ttacttggaa aaatatatta
    17401 ctttggtaat aattcaaaag cagttactgg atggcaaact attaatggta aagtatatta
    17461 ctttatgcct gatactgcta tggctgcagc tggtggactt tttgagattg atggtgttat
    17521 atatttcttt ggtgttgatg gagtaaaagc ccctgggata tatggctaaa atatatgttt
    17581 gataaaaaat tattcctgtg ctactaagaa attattttta tataataaat attgagattt
    17641 aattaaaagt catgtgttat tgtaatacat gacttttagt taaaattttt ctatcattta
    17701 ataatctatt attcttgact attttataat aaaattcata tatggaaata ttaatactaa
    17761 ataattaata gttgataaaa aatagataat atgctaaaag caaaaactaa tttagagcct
    17821 tgtaactgtt tatttgcaat tataaaaaca tctttaaaca tattgactat aatataaaat
    17881 attaactata atacaaaaca atattaatta attttctcta cagctatccc tggtatagtt
    17941 atatttccac ccatagttga ttcataagtt atagttccag cacttatacc tcttatagtt
    18001 atgtaatcat cctctaatac tcttgaagga gttattgatt ttttataact acatagtaca
    18061 accttatcat aatttccaga cacagctaat cttatttgca cctcatcacc atcttcaata
    18121 acttgaataa ccttaccttc aaattttacc tttttgtact tataatcatc aggtgttcta
    18181 gctaattggt cataagtaat accagtatca tatcctttct tctcctcttc ttcttttttg
    18241 cgttgttctt cagccttttt agcttcttca gcttttttag cttcttcagc tttacgttga
    18301 ttttcagctt caatagcttt cttttcgtcg tctttcattt tgaaccatgg ttcagcatca
    18361 gacaatttgc tatttaaagt ttctatttct gttttttgag aatctataac tgatgtttgg
    18421 ttagaaatga cctcctcatg gtcttcagaa caagctggtg aggatatatt gccaaaaaac
    18481 acgcctaaaa taaatgccag tagagcaata ccctttgtgc tcttaaagaa tttaattatt
    18541 ttcttagagc ttccttttcc ttcattacta aattcgttac catcattttt tttagaaaac
    18601 ataatacaat ctccctttta ttagatatat tttattttaa aagttaaaaa cttaaaataa
    18661 ctagttgact aaaaattata tattcatatt ttcctaaaat atatttcccc taagcataat
    18721 tttacaaaat aaagtaagaa gattcaatat attttgaaaa aataagataa aaatgtcaga
    18781 ttataatata attttcttga aggtgaattt tatatattaa attaaacata aagtatttta
    18841 tttgtataaa actatattat gatgtaatta agtgactcag tgatttagag gtggtaaaat
    18901 atatatatat gaaagagcat aaataaattg atataataaa aaattaaata ttaaatatta
    18961 actataataa aaaaatatct ggtaataggt ataatataaa aagaatatac cagaaagaag
    19021 gtgaagtatg ggagaactac aaaaaattcc aggggtaggg aaagcaacag aaaaatcttt
    19081 aatcatgtta ggatatacaa ctattaaatc acttaaagat gcaaacccag cacaaatgta
    19141 tgaaaaggaa tgtttaatac gtggacagca catagacaga tgtcagttat atgtatacag
    19201 atgtgcagta tattttgcat caactgaaaa tccagaacca gaaaaattaa agtggtggta
    19261 ttggaaagat taaaaaatca aaaaagttag acataaaaaa gagttgaata tccgttttaa
    19321 ataataaaaa ctaatactca actctttttt agtcgtaaat tttatgtaaa tctatttgta
    19381 tggctaaata tacccatcaa taaatgtata aatataccaa tcaacaaatg actaaacata
    19441 ctacctaaca aaggattaaa taaattactt aacaaagcat tctaaaacaa ttaattagaa
    19501 actgtttctt caagccattt tctacattgc tcaatattta ccatagggtc aaaaccttgg
    19561 tcttttccct tatttaaaag catatcacaa gggaaagtat cacattcacc acaatgatta
    19621 agttccttac tttcacagca agttttaacc ttacattctc caccccaaaa tggtttttcc
    19681 atagttgggc aaccagtgca atttacttgt tctttttttg tacaactgtc acaacagaca
    19741 ccacatcttg attcaaacat gttcaaacat cctttccatt atttaaaaat attataaaat
    19801 gattttagat gaatacaaaa gtgcaaatag ttgattttag gtcatctaaa tgttaaacat
    19861 aaaattatta gtactggtaa atttataaaa actattccaa aaatcttttt gaatatttca
    19921 aaacacaata aattacttca aatccctttg aatatatttt acagcattat agattgcttt
    19981 aaatctcttt gaatattcta caagactata gattagttta aatccctttg aatatatttt
    20041 acaacattat agattgtttt aaatctcttt gaatattcta caagactata gattagttta
    20101 aatccctttg aatatttcaa aacaccatag attactttaa atccctttga atattctata
    20161 acactataaa ttacttttaa cttttatata accataaagt ttttatctgg cactttaaat
    20221 ggagttttat atcaaatttg ccttccatcg aataaccaaa cttaatttaa ttacacattc
    20281 caagagtcaa atattcattc aatatatttg ataattctat gttatagcta taattaaata
    20341 tagattatta aagttaaata tttatttaat atattgaatg attttttacc tatatttaat
    20401 taagtttcat tatataatat aaaaattgtt tttgcattaa gttttaatat aatacataat
    20461 aattttaaat aataacatta ttatatattt tttaatttta ggagtatatc tattatatag
    20521 cgagtagata aaacatataa aattcaaata aaagatatat atttttaaat aaaatggata
    20581 tagatttcaa ctaaaaagaa tataaatttc aaaccccaaa atatctagca tttaccatta
    20641 agaaataaca tcattctttc taaaatttct attggcaatt tcagaaaata ctatagtagt
    20701 aataaatgca acacatattg taactatagt gtcattaaca tttaaagcag attgctttat
    20761 aacccccata gcactaccta acatagaata agggaaaaat ataccaacag caggttttgc
    20821 tactattaat cccataccaa atagagaaag gcaaagacta ataccaatag gagttgcaaa
    20881 acttctaatc tttatagaca tgtataattg tatagaagct attgaaatag aaataatcca
    20941 acctttagca atccaaccag tcaattcttt aggtacacta ccagaaaaac caaacatatt
    21001 tcctgcaact atataaaaga taacaaagaa aacttgtgta atagctgtaa gtattgaaac
    21061 tactgtaagt ttagataaaa agatattttt taaattaact ggcagtgtca ttacattatt
    21121 ccaattatga ttcatatgtt caagcctaca aatatatgca caaaagattg cgattaagat
    21181 aggaaagaaa aattccccat aaaaaagact aacttgagtc cataagctgt accattcttt
    21241 tttgagtatg ccttgattta gataaaaatt accagaacca atcaacacac ttataagtgg
    21301 caaagctaat aatacatacc atataaaaga attttttaac tttagaattt ctcccaaaac
    21361 tgacttcctt aacatttaaa tccctcctat acttcttttt ttaataaatg atttcttcca
    21421 atataataaa ttagcattcc aattaagaaa actaaaatcg taatagaaaa attcatatca
    21481 attctataga cagatgaacc taaaacatta tcataagcat aacttaaagg tgataactct
    21541 aggtaataag accatataaa caatctacga ataccttgat aaaacaaacc tgatgtcaaa
    21601 cctataaaac taccaatcat gccaaatgta attgcaatca tttgatttgg aattacagtt
    21661 gcaatccata ggtgtagtgc aatgatagca atacttacaa gaattgttcc taatgtgtat
    21721 tttaaaagta aagatacaga aattgactca ataacccctc taaaatgtcc aaacaacaca
    21781 atagataaca cttgcatcaa tacaggtata gataccaaaa tagcagaaca taaaaattta
    21841 gataaataaa tactatttaa agatgtcaca gaagatttta aaagcttcca tgtatctcct
    21901 ttatgttcta tatcgcttat acgtgatgta attattgata ttaagatagg aaagaataga
    21961 ccatttaaac ttgcaaaact cataaacata taggaatatt caaatccacc taacatatct
    22021 ggattacgtg taatagctct atttgaattt atgatacacc acattatttc aacagctaca
    22081 aataaaaagg tcatcagaat aatcttcttt cttttaagtt tataaaattc tagaccaagg
    22141 tatttcatta taaagtcacc gccttaccag taagttctaa gaatatatct tccaagcttt
    22201 ttttatgttc ttctattcta aatacatcta tatttgaatg gacaagcata ccatttattt
    22261 tagccacatc tgagtctttt aaattttcaa tagtcaagta cccatcttgt ataagtgaca
    22321 tatatccttt agtatttaat agtttttgtg cagatacaac attcttagtt ttgatagcaa
    22381 tctgactttg acctctatta tgaagttctt ttatgctatc ttgaaaaacc agttcgccat
    22441 gatttattat tcctattgat gtggcaattt ggtcaatttc acttaaaaga tggctagaga
    22501 ttagaacagt catcccgtat ttttctggta gagattttat taattctcta atttcctcaa
    22561 tccctgctgg gtcgagtcca tttgtaggtt catcaagtat taataatttg ggaaacttca
    22621 ttattgccat agcaatacca agacgttgct tcatacctaa agaatattga ctaacttttt
    22681 tatttttttg attttctaac cttacaattt ttaatgcttc atttacattt tttttaggta
    22741 aatctaagag tttttgcatt atggtcatgt tttcaagccc tgtaagatga ccatagtatg
    22801 atggagattc tatcaaagaa cctatatctt ttaaaattga tattctattt ttttcattta
    22861 actctttacc taaaatatta atatttcctt gtgtgggttt agcaagtcca agaagcattt
    22921 taagagtggt agattttcca gctccattag gacccaaaaa accatataca gctccttgtg
    22981 gaactcttag gtctatatcc tttactctaa atattttatt gtattccttt gaaagtcttt
    23041 gtgttctaat tatcatttcc atatgtttca tccccttttt taatctgtgc ttattgattc
    23101 ttttaactta tatcagtata ataacttggt tacatttcaa ttagctgaaa tttaccttac
    23161 aataacctta aaagtctatt taggcaaagt tgtgaaaatg ggtatatggt atactaaagg
    23221 agggtgatga ttatggagtc aataaaagat aaaaaaatac ttgtggttga tgaccacaag
    23281 gaattattaa aaatgataga tgaaatcctg agaaaagagg ggtttagtag agtattttta
    23341 gcatcaagtt atgaggaagc tgttagggta tttagaaatg taaagccaga ttgtgcaatt
    23401 ttagatgttg tattgccaga tggagatggt ttttctatta tgagaaaaat tagagagaca
    23461 tctaaaatac cagtgatttt tctctctgca agaggtgaag atgaagatag attgattggt
    23521 ttgggcttag gggctgacga ttatatagta aagccatttt taccaaagga acttacttta
    23581 aggcttgtgg gtatattaaa tcgtgtatat gtgcctatag aagaagagga gttgccagta
    23641 tttaaactgg gagattctgt tgttgtgaat ttaaatagtg catgtgttga gaaagatggg
    23701 caagagattt ctttaacagc taaagagcat tcgttgcttt taaagttgta tgaaaataaa
    23761 gggagaattg ttactaatga ttcactatgt caagccattt ggggagatga tatgtatgga
    23821 tatgaaaata cccttatggt tcatgttaga agggttagag agaagataga aaaaactcca
    23881 tctacaccta aacatcttat tacagtaaga ggtcttggat ataagttgat gattaattaa
    23941 ttttagatat tagaataaaa gaaatcaaga ggagtgattt aattttggat agtgtaaagt
    24001 acatattgag gcgatttata ggttcaagta tcttgatttc attacttttt attgtattaa
    24061 atatagcagg ttttcttctg ttttcatata tgctatttgt atctaaatac tctgataatt
    24121 tagatacaag tgatagcaga gaaataaaat caaacttgat tatgattgaa gataatttga
    24181 ttttaagaaa tggaaagttt attttagatg attctagtaa ggaagtacta cataaaaata
    24241 aagtttgggc aatgttaatt gataacaatg gagatagaat atggggattt gatttaccaa
    24301 aagaaattcc aagtcattat actttgacag atgtagcaaa gttttcaagg ttctttttaa
    24361 aggactatcc tgtgtatgta tgggaacatc caaatggaat attagtaaca ggttatccaa
    24421 aagacaagta cactaagttt aaccttactt atacggttaa ggaaatagaa caatttccta
    24481 tgttaataat aggtatgttt ttggttaatg caatagttac ttttttaata gctctattca
    24541 taggtttaaa aatggtgaaa tctataaaac caattattac tggcataaag cttatgtcaa
    24601 aaggagaacc agtactttta caagaaaaag gaatactaag tgatatttca aaatctatta
    24661 atactgtatc taaagagttg caaatgaaag atgaaaaact taggaagaaa gaggaagcta
    24721 ggtctaactg gattgcagga atatctcatg atataagaac tccactttca atgataattg
    24781 gatatgctgg agaacttgaa gaaagcagta gcctttcaaa tagagaacaa gagcaagtgt
    24841 ctattatatg caatcaaggg attaaaatca gagaattagt aaatgaccta aatttagtgt
    24901 ctaaacttga atataatatg caagcattga attgtgataa gattagagtt tctgcgtttt
    24961 tgagagagct tatttctgag tttataaata ataatttgga taatgacttt tacgttgaat
    25021 ttgatatact aaatgaagat attattatag atgcagataa aaaattatta aaaagggcta
    25081 ttagtaattt aatacaaaat agtataactc ataaccaaca aggatgtaat ataagggtta
    25141 cctctaagtc tgatttagat ttttgctata taattgttga agatgatgga aaaggtatga
    25201 gtcaagaaag aattaatagt ttattaaaga gccaaaatgg actaagtgag gcatatgcca
    25261 aaggtcaaaa tcatggtcta ggtattttga tagtatctgg cattattaat gcacatagag
    25321 gtaaattaga tattacgagc attgatagtc agggactaaa aacaatacta aaattacctc
    25381 taattaagtg atattttata aaataataac agataagaat gaagaatgaa aatattttga
    25441 aaataatttt attctttatt gacaaattaa ctctattaga gtagaataag gataaattct
    25501 tttcttgtca agttttatta aagtaaagag taacttgtgc tttatgcgct tatggctgag
    25561 ttactcatgg tatcaaaatt ttcatagaaa taatattttg gaattattgt aaggttatta
    25621 aattctttag ataattccat tttttttatt ttttagttaa tatttaattt tattattgac
    25681 aaaaaaattc tactaaaata gaattatggt atagtgtttt ttaattttaa gaaaaaatat
    25741 aatgacatcc taaaaaagtt ttaattatac gctgttctgt gtagttataa tagcttctat
    25801 gtaactattg taagtatatt attatagtta tttatttaaa gtacgataaa tgttttaaat
    25861 tgaagtattt tgcgccattg agttctacta aagtagagtt tttgtgtagt atttttagaa
    25921 ataacatat
//
LOCUS       DAMJVG010000055        25843 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.055, whole genome shotgun sequence.
ACCESSION   DAMJVG010000055 DAMJVG010000000
VERSION     DAMJVG010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 25843)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25843)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25843
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.055"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            198..641
                     /locus_tag="PC512_002467"
     CDS             198..641
                     /locus_tag="PC512_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2442204.1"
                     /translation="MIEIKTIEINKKSQIDLLILADPCEEMIDKYLNKGTMYALYDNK
                     ELTCIAVVNEISKEICELKNIATYEHFQNMGYASKMIYHLLDVYSKKYSSMVVGTSES
                     GVPFYEKFGFVYSHKIKNFFVDNYPEPIFEGELQCVDMLYLSYNF"
     gene            813..983
                     /locus_tag="PC512_002468"
     CDS             813..983
                     /locus_tag="PC512_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442205.1"
                     /translation="MDSNNNTIKSTVKKGISFGSCLAMIISYTAWKSIPWAIFHGLMS
                     WIYVLYYWVKYA"
     gene            1356..2477
                     /locus_tag="PC512_002469"
     CDS             1356..2477
                     /locus_tag="PC512_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HDF2442206.1"
                     /translation="MKEKLEEKSKIIKTSKEYKRTIIEEKDREWTQKLNDILSRGDFS
                     NEKLDKIKDLIPKEILTSENVGEVVTEDGYAKPEYDEVFKSLFTLNNDYDLLANFIND
                     ILKDAPYANRNIKQFTQIKRIIKVETDPTINYIGEKRPRLDILAEDEERNHINIEMQR
                     ALEEDYLERAEYYLSRVHGRKLEEGKEYKEIGKTVGIHILNHVKYNHIEDYVNCLRLT
                     MDGHPDIFSSKTALYFIELPKIRKSSCIANRVLIWGKLIDNPSHIDIRILSKTDYVIK
                     RALDRLKELGSNEDYLLNLKRGAYIMNKSRNFKEEIFQEGIEKGIEKGIEKGIAKGKR
                     EEKFNIIIKLKNKGYNLSEICDIIDDLNKSEVEKVYNQN"
     gene            2682..3170
                     /locus_tag="PC512_002470"
     CDS             2682..3170
                     /locus_tag="PC512_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3841 domain-containing protein"
                     /protein_id="HDF2442207.1"
                     /translation="MKFYTIQTLEFWNNNKNNKYLSNDYSFILEDFDIPYKWMYSQMT
                     NRIYEFDDSMIWVWTKRPDLRCSGYLEKGKKGVLLEIEISEDNVLLSEFDLWHLPLMD
                     ITVELYEDEQIEKKVSWERIFDLELCSKLNEVNIEDLTLQGVTSKVPLSNVKLIKEFV
                     AK"
     gene            3256..3663
                     /locus_tag="PC512_002471"
     CDS             3256..3663
                     /locus_tag="PC512_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442208.1"
                     /translation="MSKQQTGIKSTLISEILGISYCIGATLVNKYFFKGSSIEYLPII
                     IWVLAMGAQWVYNKKYDDLIDEASKCILSRVNDIAIKVLFFSVAIVSIFLVTLDINVS
                     NLNIGMSLLVILFIQSLLKLILFIYFDRKGIYN"
     gene            3664..3882
                     /locus_tag="PC512_002472"
     CDS             3664..3882
                     /locus_tag="PC512_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2442209.1"
                     /translation="MSVLLKTKIKSYREKNLMTQGELAKSVGVRRETIVHLENGRYNP
                     SLKLAMDIAKVFDTTVEELFEFIEENNI"
     gene            4956..5251
                     /locus_tag="PC512_002473"
                     /pseudo
     CDS             4956..5251
                     /locus_tag="PC512_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427875.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            5659..6348
                     /locus_tag="PC512_002474"
     CDS             5659..6348
                     /locus_tag="PC512_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2442210.1"
                     /translation="MDILLVEDDKNIREMVYDFLISENYSVKTAIDGNTAIEIFKNYS
                     FDIILLDLMLPKSSGFEVLKYIRSVSVVPVIITTAKDSDTDKMLGLNLGADDYITKPF
                     SIVELLARIKANIRRATVYSSSRNSQDMVIRYKDLIINISKYVVSKNGIDLNLTHTEF
                     EIVKLLATNQGRAFSKEQLYNAIWKEPYYGNENVLNTHINRLRNKLSDGIEKNNYIKT
                     LWGIGYKMEEE"
     gene            6348..7265
                     /locus_tag="PC512_002475"
     CDS             6348..7265
                     /locus_tag="PC512_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF2442211.1"
                     /translation="MELFLVVISIVLFALYLKERNKSKKMESDYKYINSRLRDITNDD
                     EINYILVPSDISIVKETAVDINKLVEKFYSRQINYNRSEKAILQIFTNISHDLRTPIT
                     VLKGYIEMLYLQSQKEELSSSMRAIVEKMQTNSNELVNSINNLFNMAKIQSGDMILNL
                     QKSNLTQLCHEIILEFYDLLDKENFNVEVNIEDRPIYANVDTEALQRILKNLIDNAIK
                     YGSDGRFLGISLYEKEKHVFIDIEDKGSGISETEKEHIFTRAYTADRKKGNGLGLAIS
                     QGLANSMGGSIYVNSRPNVKTVFTVKLKS"
     gene            7338..8264
                     /locus_tag="PC512_002476"
     CDS             7338..8264
                     /locus_tag="PC512_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2442212.1"
                     /translation="MNYIIETHQLKKIYKDKAVVNAVNIHVKKGEIYGFVGPNGAGKS
                     TVMKMLLNLVNPNSGEIVMFGKKVAETDFEILKKIGTIIENPYLYENLTAKQNLDLHC
                     EYMGYYNKEHISEVLECVGLSKQSNKKVSKYSLGMKQRLAIARAILTKPELLILDEPI
                     NALDPEGIREMRELFRKLNTDYGITIFISSHILSEVEQIADTIGIIQDGKLIKEISMS
                     DIHKYQTDYVEVDVDNVELAGYLLEKEFGIKDFKITSESCIEIYDLRKDVKEISKIFI
                     QNQIGINSIGRKQSSLEDYFFQTTGTGGKETL"
     gene            8261..8941
                     /locus_tag="PC512_002477"
     CDS             8261..8941
                     /locus_tag="PC512_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2442213.1"
                     /translation="MIHLMKLELKKVGLKRYFLFSMLGIFLCMFFVFTGLNDKSTSIY
                     DYDVTFRTISLFFCFYYIILFAVLNVAYIINEYTNKTILILFSYPLDRKKLILSKLLL
                     ITTLMISSMIVGYICCFTFVVVLDKYFNLVIGDFHISILSYWIPGAIKSIIVFCSLGI
                     WTFVVGMIRKSIPVTLVSSIIFINLRQFILAGTNTTQDSLISVFIIVGITVIGIYYIL
                     NHKVTEID"
     gene            9039..9374
                     /locus_tag="PC512_002478"
                     /pseudo
     CDS             9039..9374
                     /locus_tag="PC512_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427885.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
     gene            10478..11128
                     /locus_tag="PC512_002479"
     CDS             10478..11128
                     /locus_tag="PC512_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2442214.1"
                     /translation="MKVKSNLDEILYHKIIESLIRGEYSVGQKILLNDLCEKFEVSRT
                     PVVQAVKMLNKDGVLTIMTNGKVYVPEYEYDMVKQVCETRTLIETYALEKMMQEEEEV
                     FQQKLDVIKRYSDKCEEYYRQEKSVELALADLELHKAIVEGANNEILNDVYVGIQGRF
                     IVVNYLIRPLKNRNYEGTVQDHFEILKFIEDRDTKKAVDKLRNHIQGTIKRFCEDE"
     gene            11455..13521
                     /locus_tag="PC512_002480"
     CDS             11455..13521
                     /locus_tag="PC512_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HDF2442215.1"
                     /translation="MKEVVESLKKITKERIENTMKKLFTSETFLEYQFISDCQISPDG
                     GYTAFIVKKADIKENGYTSQVYILNNKTGELKQITSINSVGAYAWEDENTILFPALRN
                     EKVKEAVKNGKQCMSYYALSLNGGEAEELFRLPIKGGKLNPIGKGLYAVIDSYDNDRP
                     IVEGLPEEEQQKKINAYNKRHYEHFKEIPYAVNGEGYISRKRKRLYVYDSNINELKAI
                     TAPMFNVVGMKISDGKILYIGQEFKDVKGLKNGVYVFDTNTNTNVCILEKDKYIIKGF
                     ELYQNQVILNLTDALSYGNGENGDFYTIDIDTKEMKLLSGHQHHCIGNTVTSDVKMGA
                     GQTTKVDGEYIYYTSTVDMDCIIERIHIPTGKQEKVTQTGSVDFIDVKDGNIVCVGCL
                     GNGLPEVYTVENGTLCKKTHLNDHILEEYKISVPEYIESKGSSKWEIQGYVYKPVDYE
                     VGKKYPAVLAIHGGPRLTYGPYFMHEIQVFTSAGYFVFFCNPRGSEGRGNAFADIRKQ
                     FGDIDYIDFMEFTDTVLEKYTDIDKTKLAVEGGSYGGFMTNWIIGHTNRFAVACAQRS
                     IANWSGMEGTTDIGYYFCKGQTGASHMENHELQWKQSPLAYADKCVTPTLFLHGEKDY
                     RCYMQEAFQMFSALKIHGCPTKLCLFEGENHELSRSGRPKQKLQRLVEMLDWFSVYIK
                     KDNIGQ"
     gene            13538..15493
                     /locus_tag="PC512_002481"
     CDS             13538..15493
                     /locus_tag="PC512_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HDF2442216.1"
                     /translation="MEKIKIENSDIFEYIFPHDISCSPDGKHIAYIISNINEEKDCYE
                     HDLYVMDIKTEKQIHMTQTKDVTSFSWISNTELLFTSKRNKPKSGTTDFYTISIEGGE
                     AKKAFSIPKACSVPVSLGNKLWLLTTKNPTDSKKSEPDRAVEGVDYWTFTDKPFIRDG
                     ENFSQRRRVTLELYQEGENITKAITPKFCEVAGVDVSSDKNRILYTGQIYEDCATPFS
                     GLWEYHIDSGETKELVPQGKYQISLAKYIGKDKVMLQASTLDRSITQNHDIFILDLST
                     NEINMIASPDGMYATLLDVDAVYGGGRSNKVIGDKFIGARICRTMTEFNEFDTKTGNI
                     RIITKVDAFTSFDIYDNTMYTVMLKDYELAEIYSIDMTTGTMKKMTAFSKPYLDTHKV
                     SLPEKLTFVAKNKEEVDGFVIPPIDAKEGEKYPAVLFIHGGPKWAYGYMFTHLKQCVT
                     SKGMYVIYCNPHGGDGYGEKFLEMVERWGYVDYEHLMEFVDTCIEKYPGIDADRLGVA
                     GGSYGGYMTNWIIGHTDRFKAAVSQRGISNLITASLIIDFGDRIMKQTCGDKTPWNHE
                     EVLWNHSPIKYVKNVKTPTLFLHSDRDYRCFMGDTFQMFTALKQLGVDTEMYLFHGDT
                     HGLSRNGRPSNRIARANAIVDWFERYL"
     gene            15509..16699
                     /locus_tag="PC512_002482"
     CDS             15509..16699
                     /locus_tag="PC512_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HDF2442217.1"
                     /translation="MSDMLLWFSVVLVLFAIGDLIASKTKAKVSAVFVTLLLFLILFV
                     TKAIPADIIEKAGMTAAASWSVPMIMFSMGTMLNVKQFIDEWRTVLTAWLGIVAVIVC
                     VSLCIPLFGKSTVLTSIPVINGALPATTIMTQAALEKGLTLAAATATVVFAIQKFIGT
                     PIASRAALQEANRLLVEYHEAKSKGIDLANVDTDKKEAENTGTKVKQAFCEKYDKYYS
                     TNVCIFFIALFSYLGYELSEIIHVNYSIVCLVVGVIVTRIGIVPKDILEKGKIKGFIN
                     MVVFAAVIPSLAKVSLTDLISLFVPIVGMFAASIIGIFLMMKVLPGWKIIGSKPLAFG
                     VGFCQMLGFPTTYLISNEVCNAVGETEEERAYLMSKIMPKLVVGGMACMISIVVAGLM
                     VPML"
     gene            17848..18222
                     /locus_tag="PC512_002483"
     CDS             17848..18222
                     /locus_tag="PC512_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2442218.1"
                     /translation="MKVLISNTSDKPLYQQIKEQIKEAIFTEELKEGDAMPSIRNFAN
                     DLKVSILTIRRVYEELENEGFLTRQVGIGTFISTGNLEILRDSKRRIVEQKMADMIKD
                     AKALGITQIELQEMMDILYEED"
     gene            18224..19081
                     /locus_tag="PC512_002484"
     CDS             18224..19081
                     /locus_tag="PC512_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2442219.1"
                     /translation="MENILEVYNLNKTYTDFSLSNISFALPEDCITGFIGVNGAGKTT
                     TIRSILDVVKRDSGKIKIFGKDFDGNEKELKNRIGVVFDDSYFYEELSMAEMKSIIAP
                     SYDNWCEEDYQQNMKRFNLNPKQKIDTLSKGMKMKFALALALSHKAEFLIMDEPTSGL
                     DPLIRSQILDILTGYMKKCGRGVFFSTHITSDLDKIADMIVMIDNGRIILEREKDTLL
                     DEHRKVKGDIQFLNDETKKLFLNLEITGYGFIGITSKINEVQKNMPDILIERPTIEDI
                     MLAYIERRE"
     gene            19084..19722
                     /locus_tag="PC512_002485"
     CDS             19084..19722
                     /locus_tag="PC512_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HDF2442220.1"
                     /translation="MLIHLVKKDILIVKKYVLLILFIAIGIPLFILWRLPPFAQILGF
                     VLSIIFSEFMLCQYLLLKESQYSKASVLLCSTPYPRRGLVQSKYVLFAMVFIYCTLVY
                     WIENLLIPQIGTFDLTYILIVLLISSIIYGVYMPIQYKLGYETTKFFFVMIIMASSFV
                     LPLTIAHSNFEIPFIYQYPSMIVNIVLFLLSLIILLASMFISIKIFSNKELV"
     gene            20728..21462
                     /locus_tag="PC512_002486"
     CDS             20728..21462
                     /locus_tag="PC512_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2442221.1"
                     /translation="MNLAKGLDVLKISSNVFGEDKVMYIPVIYTEDDATLIDTGLPGQ
                     GDLIIDALNKSNTSFDKLKNIIITHHDIDHIGNINYLREKSKNNIKVYAYKSEISYIT
                     GEETPFKLYMLEQMVDKIDDKMLSMLNVMGLGFKSSYTKVDVSLDNHEKLNLGEEIEV
                     IHTGGHTRGHICLYLKESKVLIAGDLLQVENGELKPVDVMYSNKQELKDAIKNISNYD
                     IETIVFSHGGLYQRNIIGTLKNLIIE"
     gene            22258..23514
                     /locus_tag="PC512_002487"
     CDS             22258..23514
                     /locus_tag="PC512_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HDF2442222.1"
                     /translation="MIEKFKTLIWIKMIIRIKSVYKTYGGLFFLGLIGIPVGAIIGLI
                     DTIFGTVLLKVTDIRETYPMYLIPFLAVVGVVIAYCYFKFGGKSSKGMNLIFEVGHGE
                     EEIIPLRLVPFIISGTWLTHLFGGSAGREGVAVQIGATFSHWVGKRLPIKNASSIFLV
                     TGMAAGFAGLFETPIAAILFAMEVLVAGSLEYQSLFPAFTASFTASAVSKALGLEKFS
                     FALSSKVVFDLSIFWKLIVLGIIFGMVGGAFAWCLKLSKRKIGNRLKNPMIRIAIIGV
                     CLSVLFLLFYKGRYSGLGTNLIQNSFYGGEIYSFDWLLKFILTILTLSAGFQGGEVTP
                     LFSIGASLGVLLAGFFNLPIELVAALGYASVFGSATNTFFAPVFIGAEVFGYSYLPYF
                     FVVCAISYIFNMDKSIYSLQKISTKQ"
     gene            23577..24770
                     /locus_tag="PC512_002488"
     CDS             23577..24770
                     /locus_tag="PC512_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HDF2442223.1"
                     /translation="MLTSLALIFLLGMASGGIFKRIKLPNLLGMLLTGIILGPYVLNL
                     IDNSILDISSDLRKIALIIILTRAGLSLDINDLKKVGRPAVLMCFIPATFEIIGMIVL
                     APKLLGVSILEAAVMGAVVGAVSPAIIVPKMLKLMEEGYGTEKSIPQMLLAGTSIDDI
                     FVIVMFTVFTGLAQGNSISAISFLQIPVSIILGVIVGAVIGIYLAVFFKKVHMRDSAK
                     GVLLLSISFLMISLETALEGIVPFSGLLAVMSIGIFLQIKYRVVARRLSIKYSKLWVG
                     AEILLFVLVGATVDISYAFKAGIGAVILIFGVLLFRMVGVFFCLIKTNLTIKERLFCM
                     IGYIPKATVQAAIGGVPLAMGMASGQLILTLAVLAILITAPLGAFGIDVTYKKLLTSV
                     KGENK"
     gene            24971..25351
                     /locus_tag="PC512_002489"
     CDS             24971..25351
                     /locus_tag="PC512_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2442224.1"
                     /translation="MCLKKLSKLELVIMKFIWNLDIKTNSYEIIDYMKEEHNLPEKVA
                     LKTLSKLSKKRFLYVQETGKCMYYTVAIKEKAYLEFISRNVQNLLKNNFIRNLLVSFH
                     EEELTEEKIKSLENWVVNWEEAYV"
BASE COUNT         9851 a         2703 c         4366 g         8923 t
ORIGIN      
        1 ctaatattat agatgaatat tagtattgat attctaggta attgctagag ctgatattat
       61 aatttattat taatattaat attctaggga attatcacta tattttaaaa agtaaaaata
      121 tatatcaaaa tgaactaaat aagtactgta agaagtttgt taaattaagg tttgaataaa
      181 gtgagggtgg agaacttatg atagaaataa aaactataga aataaataaa aaaagtcaaa
      241 ttgacctttt aatattagct gacccatgtg aagaaatgat tgataaatat ctcaataaag
      301 gaactatgta cgcattgtat gataataaag aacttacttg tatagcagtt gtaaatgaaa
      361 tttccaaaga aatatgtgaa ttaaaaaaca ttgctacata tgagcatttt caaaatatgg
      421 gttatgcctc aaagatgatt tatcatcttt tagatgttta tagtaaaaaa tattcatcaa
      481 tggttgttgg tacatctgaa agtggagttc ctttttatga gaagtttgga tttgtttatt
      541 cacataaaat taaaaacttt tttgtagata attatccaga accaatcttt gaaggagaat
      601 tacaatgtgt tgacatgttg tatctatcat ataactttta gataggataa tatttttagg
      661 ttaatataat taattaattc atataattat cggaattata atttataaat tatgtataat
      721 aagagtataa tttatttaga agctgttata ttgtattaga ttcaaataag atatataata
      781 acttgtttat tttgaatttt ggaggattaa ttatggattc aaataataat actataaaat
      841 caactgttaa aaagggtatt tcttttggtt cttgtttagc aatgattatt tcttatactg
      901 catggaaatc tattccatgg gctatttttc atggcttaat gagttggata tatgtacttt
      961 attattgggt taagtatgca tagattaaat taataaataa gtatgtaata ttgtaaagtt
     1021 taagaaacaa aatgtaaggg agtgtctcga agtgaacttt tagtttataa ggcactcttt
     1081 tttgtattaa ataaaatata ttttcattac ttaaacaatg aaaaagatga gtatctctat
     1141 tttaatacat acccttatat tcattcattt atcaacaata gttttaaaaa gaaagctatc
     1201 taaaatctat tgtaatctaa gtgcttctct ttaaagtctt aactttagta atgatatata
     1261 agtttataag gttcttattt caataatgca aattttactt agaagttcag actttggtat
     1321 gaagaaatgg gtaataataa aaaagaggtg ttgatatgaa agaaaaatta gaagaaaaat
     1381 ctaagattat taaaacatca aaagagtata aacgaactat aattgaagaa aaggacagag
     1441 aatggaccca aaaattaaat gacatactta gtagaggtga tttttctaat gaaaaattag
     1501 ataaaatcaa ggatttaatt ccaaaagaaa tattgactag tgaaaatgtt ggagaagttg
     1561 taactgaaga tgggtatgct aagcctgagt atgatgaggt atttaaatca ttgtttactt
     1621 taaataatga ttacgattta cttgcaaatt ttataaatga tatcctcaaa gatgctccat
     1681 atgctaatag gaatatcaaa cagttcactc aaataaaaag aataattaag gttgaaaccg
     1741 acccaacaat taattacatt ggtgagaaaa gacctagact tgatattttg gctgaagatg
     1801 aagaacgtaa ccatataaat attgagatgc aaagagctct tgaagaggat tatttggaaa
     1861 gagctgaata ttatcttagt cgtgtacatg gtagaaagtt agaagaaggt aaagaatata
     1921 aagaaattgg aaaaactgtt ggaatacata tactaaatca tgtaaaatat aatcacatag
     1981 aagattatgt aaattgcctg agattaacaa tggacgggca tccagatatt ttttctagta
     2041 aaactgcatt atattttata gaacttccaa aaattcgtaa atccagttgt atagcaaaca
     2101 gagttctaat atggggtaaa cttattgata atccttctca tatagatatt agaatactat
     2161 ctaaaacgga ttatgttatt aaaagagcac ttgatagatt aaaagaatta ggtagtaatg
     2221 aggactattt attaaattta aagagaggtg cgtatattat gaataaaagt agaaatttta
     2281 aagaagaaat ttttcaagaa ggtattgaaa aaggtatcga aaaaggtatc gaaaaaggta
     2341 ttgcaaaagg gaaaagagaa gagaaattta atatcatcat aaaattaaaa aataaaggat
     2401 acaatttgag tgaaatatgc gatattatag atgatttgaa taaatcagag gttgaaaaag
     2461 tctataatca aaactaatac tatgattgag atggcactag ataaatacaa agcttcctct
     2521 tttaaattta aattaatata aaactttgtt atttaaatat ggtagatata aagagatata
     2581 taaataatag gtacaaagag gtgtataaat aaaggagata attcaaaata aaagtttgaa
     2641 ccatctcctt cttatagaaa aacaaagggg ttgatttata tatgaaattt tatactatac
     2701 agactttaga attttggaat aacaataaaa acaataaata tctatcaaat gattattctt
     2761 ttatattaga agactttgat attccataca aatggatgta tagtcaaatg acaaatagaa
     2821 tatatgaatt tgatgatagt atgatatggg tttggacgaa gagacctgat ttaagatgta
     2881 gtggttattt agaaaaagga aaaaaaggtg ttttacttga aatagaaata agtgaagaca
     2941 atgtgttatt atcagaattt gatttatggc atttaccttt aatggatatt actgtagagc
     3001 tttatgaaga tgaacaaatt gaaaagaagg taagttggga aagaatattt gacttagaac
     3061 tgtgttcaaa attaaatgaa gttaatatag aagatttgac attgcaagga gtgacatcta
     3121 aagtgcctct atctaatgta aaattaataa aagaatttgt tgcaaaataa tatttttatt
     3181 gaaatttatt caaaaaagtt atatatttat aacaagaggt gttataaata cataactttt
     3241 taagggggat tttatatgtc taaacaacaa actggtatta aatcaacact tatttcagaa
     3301 atattgggaa tttcttattg tattggagct acattagtaa ataagtattt ttttaaagga
     3361 agtagtattg aatatcttcc tataattatt tgggtattag ctatgggagc tcagtgggtc
     3421 tataataaaa agtatgatga tttaattgat gaggcatcaa aatgtatact atcaagagtt
     3481 aatgatattg caataaaagt attgtttttt tctgtagcta tagtatctat atttcttgta
     3541 actttggaca taaatgtgtc aaatttaaat ataggaatgt ctttattagt cattttgttt
     3601 attcaatcct tgttgaagtt aattctattt atatattttg acagaaaggg gatatacaat
     3661 taggtgtcag tattactaaa gacaaaaatt aaatcctata gagaaaagaa ccttatgaca
     3721 caaggtgaac ttgcaaagtc agtaggagta agacgtgaaa ctattgtaca tttagaaaat
     3781 ggtcgctaca atccttcttt aaaactggca atggatattg ctaaggtatt tgatacaact
     3841 gtagaagagt tgtttgaatt tattgaagaa aataatattt aaatttcatg tattacttat
     3901 gcattagaga atgaattaat tataggtaaa aaaccaagct tatagattag agaataaatg
     3961 acttatagat gaaaaaccaa gctaatggat taaagagtga atgatttata gattaagaag
     4021 taagcttata gattagagaa taaatgactt atagatgaaa aaccaagcta atggattaaa
     4081 gaatgaatga tttatagatg aaaaagaaag cttatagatt agagaataaa tgacttatag
     4141 atgaaaaacc aagctcatag attaaagaat gaatgattta tagatgaaaa agaaagctta
     4201 tagattagag aatgaattaa ttataggtaa aaaacaagct aatagattaa aaaatgaatg
     4261 atttatagat taagaagtaa gcttatagat tagagaataa atgacttata gattaagaag
     4321 taagcttata gattagagaa taaatgactt ataaataaaa accaagctta tagattagag
     4381 aataaatgac ttataaataa aaaccaagct tatagattag agaatgaatt aattataggt
     4441 aaaaaccaag cttatagatt aaaaaatgaa tgatttatag atgaagaact aaacttatag
     4501 attaaaaaat aaatgactta tttatagatg aaaaaccaaa cttatagatt aaaaaataaa
     4561 tgatttatag atgaagaact aaacttatag attaaaaaat aaatgactta tagatgaaaa
     4621 atcaagctca tagattaaag aataaataac ttattagatg aaaaaccaag cttatagata
     4681 agaagtccat gcttataagc cagaaaatga atagtttaat agattaaaaa atacatattt
     4741 gtgaattata gaatgaataa ctccataaac tagaaaattt ataataatat ctatatgaaa
     4801 attagaatta ttttatcaca aaaaaattaa gttaaataaa tatgaaatta cttccaaata
     4861 tacttccaaa aacatgtaat cgcatatata atataattat aaaaataata aatattttta
     4921 tagtagtagt taattattaa taaggagggg tcaaaatgcc tagcatgatt atggaagttg
     4981 taggagtact atttatagct attggattaa tcttgacatt cattgaaata aaaggaaatt
     5041 tcccttcttt ttatggtttt ggtcaaaatt aaaatgctgt aggtattata gcagcaggaa
     5101 ttgctttaat tttctttaga aatggcatag atacatagat tctatagcta cttatggtgt
     5161 atttttagca atagaacttg ttgtaatagt tgcatatttc ttaataagaa aaaaatttac
     5221 taaagaagat aaacatttaa gaactaatta actaaattat ctactataaa attggaaaat
     5281 taaaaacaaa taaaagtttg tttttaatta tttaaaatcc aaatttgatt atttttaaag
     5341 aaactatgtt ctgtataaaa ctagaatgtg gtttcttttt tatgtataaa atatttttta
     5401 gcaaaagtta aaaggtgttt tataatataa aatagttaat tgtagatgtt aataaaagaa
     5461 aattatgtat attttagata aagataagag agtatactat attttaattc ttttttcaat
     5521 aaagcttatt gaaaagaact ttaacttaga agagtatcac caaattgcag atacaatatc
     5581 ataagcagtt atttattgac aacccttttt aataaatata tcatttgaag tatactgacg
     5641 aaaaggagtt gaataataat ggacatctta ttggttgaag atgataagaa tattcgagaa
     5701 atggtatacg attttctgat tagtgagaat tactctgtta aaactgccat tgatggaaat
     5761 acagctattg aaatatttaa aaattattca tttgatatta ttttactgga cttgatgtta
     5821 ccaaagtcta gtggttttga agtattaaaa tatatacgaa gtgtgagtgt tgttcctgtt
     5881 attattacta ctgcgaaaga tagtgacaca gataaaatgc tagggcttaa tctaggtgca
     5941 gatgattata ttacaaagcc tttttcaatc gtagaattgc ttgcaagaat taaagctaat
     6001 attagacgtg caacagtgta tagcagttca agaaactctc aagatatggt tattcggtat
     6061 aaggatttga ttataaacat atcaaaatat gtagtttcaa agaatggaat tgacttaaac
     6121 ttaacacata cagaatttga aattgttaaa ttactagcga ctaatcaagg acgtgctttt
     6181 tcaaaggaac aattatacaa cgctatttgg aaagaacctt attatggaaa tgaaaatgtg
     6241 ctaaatactc atattaacag gttaagaaat aaattgtctg atggtataga aaaaaataat
     6301 tatattaaaa ctctttgggg aattggctac aaaatggagg aagaataatg gagttatttt
     6361 tagttgtaat ttcgattgta ctatttgctc tctacttaaa agaacgaaat aaatcaaaga
     6421 aaatggaaag tgattataag tatatcaatt caagacttcg tgacataaca aatgatgatg
     6481 aaattaatta tattttagta ccatctgata tttcgattgt aaaagaaaca gcagtagata
     6541 taaataaact tgttgaaaag ttttacagca ggcaaattaa ttataataga agtgaaaaag
     6601 cgatattgca aatatttaca aacatatcac acgatttacg aactcccatc acagtattaa
     6661 agggttatat tgaaatgcta tatcttcaaa gtcaaaaaga agaattatct tcttcaatga
     6721 gagcaattgt ggaaaaaatg caaacaaatt caaatgagct tgttaattca ataaataacc
     6781 tgtttaatat ggcaaaaatc caatctggag atatgatatt aaatcttcaa aaatccaatc
     6841 taacacaatt atgtcatgag attattttag agttttatga tttgctagat aaagaaaact
     6901 ttaatgttga agttaatatt gaagatagac ctatatatgc aaatgttgac acagaagcat
     6961 tacaacgtat actcaaaaat ttaattgata atgctataaa atatggttca gatggtagat
     7021 ttttagggat ttcactatat gaaaaggaaa aacatgtttt tatagatatt gaggataaag
     7081 gttcaggtat ttctgaaact gaaaaagagc atattttcac aagagcttat actgctgaca
     7141 gaaaaaaagg caatggttta ggtttggcta tttctcaagg gcttgcaaac tctatgggag
     7201 gttcaattta tgtaaatagt agacctaatg taaaaacagt ttttacggta aaattgaaaa
     7261 gttagaaaaa agttagattt aaaagagaga aaagacaatt ttattttgta tactgttttt
     7321 agaaaggagg gagtatgatg aactatatca tagagaccca tcaattaaag aaaatatata
     7381 aagataaagc tgttgttaat gctgttaata ttcatgtgaa aaagggagaa atttatggat
     7441 ttgttggacc aaacggggca ggtaaaagta cagtaatgaa aatgttgcta aatcttgtta
     7501 atccaaattc tggagaaata gttatgttcg gtaagaaagt ggcagaaact gattttgaaa
     7561 tattaaaaaa gattggtact attattgaaa atccgtattt atatgagaat ttgactgcta
     7621 aacagaatct tgatttacac tgtgaatata tgggttatta taacaaagaa catatatcag
     7681 aggtattgga atgtgtcgga ttgtcaaagc aatcaaacaa gaaagtttca aaatattctt
     7741 tagggatgaa acaacgtctt gcaatagcta gagcaattct tactaaacca gaattattga
     7801 ttcttgatga acctataaat gcactcgacc cagaggggat aagagaaatg cgagaattat
     7861 tccgtaagtt aaatacagat tatggaataa ctatatttat ttctagtcat attctttcag
     7921 aggtagaaca aattgcggac actattggaa ttattcaaga tggtaaactt attaaagaaa
     7981 tttctatgtc agatatacac aaatatcaaa cagattatgt tgaagtagat gtagataatg
     8041 tggagcttgc tggatacttg ttagaaaaag aatttggaat aaaagacttt aaaattactt
     8101 cggaaagttg tattgaaata tatgatttac gaaaagatgt aaaagaaata tccaaaatat
     8161 ttattcaaaa tcaaattggt ataaatagca ttggacgtaa acaaagttct ttagaagatt
     8221 acttcttcca aactacaggt acaggaggta aagaaacact atgatacatt taatgaaact
     8281 agagctaaaa aaagttgggc taaaaagata ttttttattt tcaatgctgg ggattttctt
     8341 atgtatgttt tttgtcttta ctggattgaa tgataaatct acttcaatat atgattatga
     8401 tgttacattt aggacaatca gtttattttt ctgtttttac tatattatat tatttgctgt
     8461 gttgaatgtg gcatatataa taaatgaata tacaaataaa acaatcttga ttttattctc
     8521 ttatccactt gaccgtaaaa aacttatttt atcaaagtta cttttgatta cgactcttat
     8581 gatatcatca atgatagttg gatatatctg ttgttttaca ttcgttgttg tgttggataa
     8641 gtattttaat ttagttattg gagattttca tatttcaatt ttatcttatt ggataccagg
     8701 agcaattaaa agtattattg tattttgctc attaggtata tggacattcg ttgttggaat
     8761 gataagaaaa tcaatacctg ttacccttgt cagttcaatt atttttatca atttaagaca
     8821 atttatttta gctggtacaa atacaactca agacagtttg atttctgttt ttattatagt
     8881 tggtataact gtgattggta tatattatat actaaatcat aaagttactg aaattgacta
     8941 gatactgtgg ataggagggt agttattaat tgtatcttct tgggataata atgatttgct
     9001 attatatcag ctattattaa tattattaga gttttaataa tattgcacaa ccatttgaag
     9061 ttgagccaaa gcttgatgaa ttaattgaat ggtactatag tcagagtgaa gtatctatta
     9121 aagttatagc tgaatttcat tatagatttg aattgataca tccatttcaa gatggtaatg
     9181 gtcgcatagg tagatttgtt atgctaaaac agatgttaga aaataatctt cctataaaaa
     9241 ttgtatcttg ggatagtgag gaattgtata gaaactcctt aaattcttgt agtttaggta
     9301 attatgtccc tttaattgaa tatttatcaa gtttagaaga ttttagagaa gtatataaaa
     9361 tgttatggaa ataattgttt gcagcaaaaa aagtttttat ataaatatat ttttatctat
     9421 gctatttaac gctaatttct tagttattct tagcttggac tatacccact attttaacta
     9481 tataaaatag tggatatagt ttaactatct ctttataact atttttatgt atcttagttg
     9541 tttcttaata tggggacagt tcataaaact aaaagtgatt tttaatttta tcatttataa
     9601 tttaccatta catcagaaaa atgcttatca ttagaatttt cataaaaggt acctattttt
     9661 ttcaattaac tgaatcaatt ctattagtct taatctttca tatttcaaat tgataatata
     9721 agaaaataaa aaataaaaaa ttttaaattt tttatttatt gcgaaaaaaa taaaaaggtg
     9781 ctatactttt tgtaacatat tattcaaatt attaagagat agtaaacatt tatagtttaa
     9841 tttgtagtac actagcatga tttgcagaac aatgaattaa tctatagtat aatagtttaa
     9901 tttaaagtac aacgatttaa tctatagtac actagcatga tttgaagtac aacgatttaa
     9961 tctatagtac actagcatga tttgaagtac aacgatttaa tctatagtat aatagtttaa
    10021 tttgaagtac aacgatttaa tctatagtac aataacttga tttgaagtat aacgatttaa
    10081 tctatagtac aataacttga tttgcaatac aatgaattaa tctatggtat aatagtttaa
    10141 tttgaagtac aatgaattaa tctatagtat aatagtttaa tttgaagtac aacgatttaa
    10201 tctatagtat aatagtttaa tttgaagtac aatggtttaa tctatagtat aatagtttaa
    10261 tttgaagtac aacgatttaa tctatagtac aataacttga tttgcaatac aatgaattaa
    10321 tctatagtat aagagcatga tttacagtac aataatttaa attgtagtac aaaagtacta
    10381 tcaaataaga atttctactt taaaaatatt actaaaagta attaaagtcc agtaattcaa
    10441 tataatatgg caaaagaata gaaataaggt gagagtagtg aaagtaaagt caaatttaga
    10501 tgaaatttta tatcataaga ttattgaaag tcttattcgt ggtgaatact ctgtaggtca
    10561 aaaaatatta ctaaatgacc tttgtgaaaa atttgaagta agcagaacac cagttgtaca
    10621 agcagtaaaa atgctaaata aagatggagt gcttactatt atgacaaatg gtaaagtgta
    10681 cgtaccagag tatgaatatg atatggtaaa acaagtttgt gaaacgagaa cactgattga
    10741 aacatatgct ttagaaaaaa tgatgcaaga agaggaagag gtttttcaac aaaagctaga
    10801 tgtaataaaa agatactctg ataaatgcga ggagtactat cgtcaagaaa aatctgtaga
    10861 acttgcacta gcagatttgg aattacataa agccattgta gaaggggcaa ataatgagat
    10921 tttaaatgat gtatatgttg gtatacaagg aagatttata gtagtgaact atttaattcg
    10981 accattaaaa aatcgtaatt atgaaggaac agtacaagac cattttgaaa tattaaaatt
    11041 cattgaagac agagatacaa aaaaagcagt agataaacta agaaatcata ttcaaggaac
    11101 tattaaaaga ttctgtgaag atgaataata agttttgaag ttactatata tacttatcta
    11161 ttaagttgct aaatgtagtc taagtataat ctaattatag tttaaacata atctaaatat
    11221 aatctaataa atataatcta aatatagtgt aaataagtct aagtatgaat taaatataga
    11281 ttaagtatag attaagtata gattaagtat gaattaagca tgaattaagc atggattaaa
    11341 tatactttaa attacaaata ttacaaggaa gccagaaggc ttcctaaaaa aataaccttt
    11401 ataaaatttt ttattttaaa tttaaaattt tttattttaa atttaaaata aaaaatgaaa
    11461 gaggtggtag agagtttgaa aaaaattact aaagaaagga tagaaaatac tatgaaaaag
    11521 ctatttacga gtgaaacatt tttggaatat caatttataa gtgattgcca aatatcacca
    11581 gatggaggat atacagcatt tattgtaaaa aaagctgata tcaaagagaa tggttacaca
    11641 agccaagttt atatattaaa caataaaact ggcgaattaa aacaaataac gtctataaac
    11701 tctgttggag catatgcctg ggaagatgaa aatactatct tgttccctgc tttgcgaaat
    11761 gaaaaagtaa aagaagctgt caaaaacggt aagcaatgca tgagttacta tgctttatct
    11821 ttaaatggtg gagaagcaga agaacttttt agactcccta tcaaaggtgg taaattgaat
    11881 cctataggaa aaggtttgta tgcagttatt gattcttatg acaatgaccg acctattgta
    11941 gagggattgc cagaagaaga acaacagaaa aaaataaatg cttataacaa aagacattat
    12001 gaacatttca aagaaattcc ttatgctgtc aatggggagg gatatattag cagaaaaaga
    12061 aaacgcctat atgtatacga cagtaatata aatgagttga aggcaattac agcacctatg
    12121 tttaatgttg taggtatgaa aataagtgat ggaaaaatct tatatatagg gcaagagttt
    12181 aaagatgtaa aaggtttgaa aaatggggtc tatgtatttg atacaaacac aaacacaaat
    12241 gtctgtatat tagaaaaaga taagtatatt ataaaaggtt ttgaattata tcaaaatcaa
    12301 gtgatactaa acctaactga tgctttatct tatggaaatg gagaaaatgg agatttttat
    12361 actattgata ttgatacgaa agaaatgaaa cttctttcag ggcatcaaca tcattgtatt
    12421 ggaaatacag taacatctga tgttaaaatg ggtgctggtc agacaacaaa ggtagatgga
    12481 gaatatattt attacacttc tacagtagat atggactgca ttattgaaag aatacatatt
    12541 ccaacaggaa aacaggaaaa agtaacacag acaggttcag ttgattttat agatgtaaaa
    12601 gatggcaata ttgtatgtgt gggttgttta ggaaatggat taccagaagt ttatacagta
    12661 gagaatggaa cattgtgtaa gaaaacacat ttaaatgacc atattttaga ggaatataaa
    12721 atttctgtgc cagaatacat agagtcaaaa ggaagttcta aatgggaaat acaaggatac
    12781 gtatataaac cagtagatta tgaggtgggg aaaaaatatc cagctgtatt ggcgattcat
    12841 ggaggaccaa gattgacata tggaccatat tttatgcatg agatacaggt atttacaagt
    12901 gcaggttact ttgtattctt ctgtaaccca agggggtctg aaggtcgtgg caatgctttt
    12961 gcagatatta ggaaacagtt tggagatatt gattatatag attttatgga atttacagat
    13021 actgtacttg aaaaatatac agacattgat aaaacaaaat tggctgttga aggtggaagt
    13081 tatggtggat ttatgacgaa ttggataatt ggtcatacaa accgttttgc tgttgcttgt
    13141 gctcagcgtt ctattgcaaa ctggagtggc atggagggta caacagacat tggttattat
    13201 ttctgcaaag gacaaacagg tgcttctcat atggaaaacc acgagcttca atggaaacag
    13261 tcacctcttg cttatgctga taaatgtgtt acaccgactt tatttttaca tggtgaaaaa
    13321 gactatagat gctatatgca agaagcattc cagatgtttt cagcattgaa aattcatggg
    13381 tgtcctacaa aactttgtct atttgaagga gaaaaccatg aactgtctcg ttctggtaga
    13441 ccaaaacaaa agctacaaag attagttgaa atgctagatt ggttttcagt atatataaaa
    13501 aaagataaca taggacagta gaaaggagaa tataaaaatg gaaaaaataa agattgaaaa
    13561 ttcagatatt tttgaatata tattccctca tgatatttct tgttcacctg atggaaagca
    13621 tattgcttat attatatcaa atatcaacga ggaaaaagac tgctatgaac atgacttata
    13681 tgtgatggac atcaaaacag aaaaacaaat acatatgact caaacaaaag atgtaacatc
    13741 atttagttgg atttctaata cagaactcct ttttacatct aaaagaaata agccaaaatc
    13801 aggtacaaca gatttttaca ctatttctat agaaggagga gaagcaaaaa aagcattttc
    13861 tattccaaaa gcttgtagcg tacctgtatc acttggaaat aaattgtggt tactgacaac
    13921 aaaaaatcca acggattcta aaaaatcaga accagatagg gcagtagagg gtgtagatta
    13981 ttggacattt acagataaac cttttataag agatggagaa aatttttctc aaagaagacg
    14041 tgtaacatta gaattatatc aagaaggtga aaatataaca aaagccatta caccaaaatt
    14101 ttgtgaagta gcaggtgtag acgtttcttc tgataaaaac agaattttat atactggtca
    14161 gatttatgaa gattgtgcaa ctcctttttc tggactttgg gagtatcata tagacagtgg
    14221 tgaaaccaaa gaacttgtac cacaaggaaa gtaccaaata agtttggcaa aatatattgg
    14281 caaagataaa gtaatgttgc aagcttcaac attagaccgt tctatcacac agaatcatga
    14341 tatttttata cttgatttga gtactaatga aataaatatg attgctagtc cagatggtat
    14401 gtatgctaca ttgctggatg tagatgcagt atatggtggt ggacgtagta ataaagttat
    14461 aggagacaaa tttattggtg caagaatttg cagaactatg acagaattta atgagtttga
    14521 tacaaagaca ggtaatatac gtatcatcac aaaagtagat gcttttacat cttttgatat
    14581 ttacgacaac accatgtaca cagtaatgtt gaaagattat gagttagcag aaatatatag
    14641 cattgatatg actacaggta caatgaaaaa aatgactgct ttttctaaac catatttaga
    14701 tactcataag gtttcattac ctgaaaaatt gacgtttgta gcaaaaaata aagaagaagt
    14761 tgatggtttt gttataccac ctatagatgc taaagaaggc gaaaaatatc ctgctgtatt
    14821 gttcattcat ggtgggccta aatgggcata tggctatatg tttacacact tgaagcagtg
    14881 tgtaacatca aagggaatgt atgtgattta ttgtaaccct catggtggtg acggttatgg
    14941 tgaaaaattc ttagaaatgg tagaaagatg ggggtatgtt gactatgagc atcttatgga
    15001 atttgtagat acttgtattg aaaaatatcc tgggattgat gcagaccgct taggggttgc
    15061 agggggaagt tacggtggtt atatgacaaa ctggataatt ggtcatacag accgtttcaa
    15121 agcagcagtt tctcaaagag gtattagtaa cttgattaca gcttctttaa ttattgactt
    15181 tggggataga attatgaagc agacttgtgg agataagacg ccttggaatc atgaggaggt
    15241 tctttggaat cattcaccta ttaaatatgt gaaaaatgtt aagacaccaa cattgttctt
    15301 acatagtgat agggattata gatgttttat gggggatact ttccaaatgt ttacagcatt
    15361 aaaacagctt ggtgtagata cagaaatgta tttgtttcat ggagatacac atggattgtc
    15421 tagaaatgga agaccatcta atagaattgc aagagcaaat gctattgtag attggtttga
    15481 aagatattta taataagggg gttattctat gagtgatatg ttattatggt ttagtgtcgt
    15541 attagtttta tttgctattg gggatttaat tgcaagcaaa acaaaagcaa aagtatcagc
    15601 tgtatttgtt acactacttt tatttttgat tctatttgtc acaaaagcaa taccagctga
    15661 tattattgaa aaagcaggta tgaccgcagc agctagttgg agtgttccaa tgattatgtt
    15721 tagtatggga acaatgttga atgttaaaca atttatagac gaatggagaa cagtattgac
    15781 agcatggctt ggaattgtag cagttatagt ctgtgtctca ttatgtattc ctttgtttgg
    15841 aaaatcaaca gtattgacaa gcataccagt tataaatgga gctttacctg ctactactat
    15901 tatgacacaa gcagcactag aaaaaggact gacacttgca gcagctacag caacagttgt
    15961 atttgcaatt cagaagttta ttggtacacc aatagcttca agagcagcgt tacaagaggc
    16021 aaaccgtctt ttagtagaat atcatgaagc aaaatcaaaa ggcattgatt tagcaaatgt
    16081 tgatactgat aagaaagaag cagagaatac aggcacaaaa gtaaaacaag ctttctgtga
    16141 aaaatacgat aaatattatt ctacaaatgt ttgtatattt tttatagcat tattctctta
    16201 tctagggtat gaactttcag agattattca tgtaaattat tctattgtat gtcttgttgt
    16261 tggtgttatt gtaacacgta ttggtattgt gccaaaagac attttggaaa aaggaaaaat
    16321 caagggattt atcaacatgg ttgtgtttgc agctgttatt ccttctttag caaaagtttc
    16381 tttgacagat ttaattagtc tttttgtacc aattgtgggt atgtttgcag cttctatcat
    16441 tggtatattc cttatgatga aggtgttacc aggttggaaa attatcggtt ctaaacctct
    16501 tgcttttgga gtagggtttt gtcagatgtt gggattccca actacatatt taatttcaaa
    16561 tgaagtgtgt aatgctgttg gagaaacgga agaagaaaga gcatatttga tgtctaagat
    16621 tatgcctaag ctggtagttg gtggtatggc ttgtatgatt tctattgtgg tagctggtct
    16681 tatggtacca atgttgtaga taggtttcat agttaaaaaa gtggtattaa tttataggag
    16741 aagctaaaaa gtagtattaa tttataaaat aattttatat tagttaattt gttataagaa
    16801 tattttcttt ttataattat aattttgatt ttataagata gcagattttt tatttgctat
    16861 gctaatagtt ataatttgtt tttatttgct aaaatgcaac tttaatttga tttatgtata
    16921 atatagggta tttaataata tttttgaaga atttttataa aaaattaaaa agaggagaaa
    16981 aaagggagtg ccacaaagtg aactttttag ttctaaggca ctcttttttg tacgaaatcg
    17041 aatatatttt caacgtttta aaagtgagaa agagacttat ctctagtttg agatagccaa
    17101 ttttaattat taaaattatt ttttgtttta tttatcaaag agtattcgtg ttttagaagt
    17161 tagtattttt tattttatat atacaaggtt ttccgtttct aatgttttct tttttaaaat
    17221 aattagggta ttcaattata gtaaaaggtg gatggtattt tggagtgata ttatttaaag
    17281 cacagtattg aatgttgaaa tcctcacatt ttagagtatt atcttttgta atcaaaaaaa
    17341 tcttctatac ttatagcaag gttacttctg caaatattcc atacataata atatcccaat
    17401 ttaaattttt ttaatataga gtttacctct agtctacact cttgaataac tctttcctct
    17461 atccaaattc ttataaattc atcccattta ttactattta tttattatta tctaaatttt
    17521 ttagtatgtt tgtaattaga aatggattta ttcctttatg ttttttataa atagtttata
    17581 acttaattta tcattaaaca aatcattcat acaggattac tttttctttt atatattcaa
    17641 ttcttacttt taataaatat ttaatacatc ctatcttatg tagttttaaa aagtgtttat
    17701 ggctattaac aatctctaat atttcattca tatttatttt gtcatagtaa tattttacat
    17761 cttttatatt gacaaaaaag tgctctaagt gtatagtgtg tatatgataa catcacactg
    17821 aaagtgataa aaagggggtg ataaaaaatg aaagtgctca tttctaacac atcagataag
    17881 ccattatacc aacaaattaa agagcaaatt aaagaagcaa tatttactga agaactgaaa
    17941 gaaggggatg caatgccatc cataagaaat tttgctaatg atttaaaagt tagtattttg
    18001 actattagac gagtgtatga agaacttgaa aatgaaggct ttcttacacg ccaagttgga
    18061 ataggaacat ttatttcaac tggaaattta gaaatactaa gagactcaaa gagacgtata
    18121 gttgaacaaa aaatggcaga tatgattaaa gatgcaaaag cactaggaat tacacagata
    18181 gagttacaag aaatgatgga tattctatat gaggaggatt aatatggaaa atattttaga
    18241 agtttataac ttaaataaga cttataccga tttttcatta tctaatataa gctttgcatt
    18301 accagaagat tgtataaccg gatttatagg tgttaatgga gcaggaaaaa caacaacaat
    18361 ccgttcgata ttggatgtcg taaagcgtga tagtggaaaa ataaaaatct ttggtaaaga
    18421 tttcgatgga aatgagaagg aattaaaaaa tcgaattgga gttgtctttg atgattcata
    18481 tttctatgag gagttgtcaa tggcagaaat gaaaagtatt attgcacctt catatgataa
    18541 ttggtgtgaa gaagattatc aacaaaatat gaagcgtttt aatcttaacc caaaacaaaa
    18601 gattgataca ctttcaaaag gaatgaaaat gaaatttgct ttagcattag cattatcgca
    18661 taaagctgag tttttaatta tggatgagcc tacaagtggt ttagacccac taatccgtag
    18721 tcagatactt gacatactaa caggatatat gaagaaatgt ggtcgtggtg ttttcttttc
    18781 cactcatata acatctgatt tagacaaaat agcagatatg attgttatga ttgacaatgg
    18841 acgtattata ttagagcgtg aaaaagatac tctattggac gaacatagaa aagtaaaagg
    18901 ggatattcaa tttctaaatg atgaaaccaa aaaattattt ttaaatttag aaattacagg
    18961 ttatggtttt atagggatta cctcaaaaat taatgaagtg caaaaaaata tgccagatat
    19021 tttaatagag cgtcctacaa ttgaagatat tatgcttgca tatattgaaa ggagagagta
    19081 attatgttga ttcatttagt taaaaaagat attctgattg taaaaaaata tgtattgttg
    19141 atattattta ttgcaatagg aatcccatta tttatattat ggcgtttacc tccatttgca
    19201 caaatattgg gatttgtact atcaattata ttttcagaat ttatgctgtg tcagtatcta
    19261 ttattaaagg agagtcaata ttcaaaagca tctgtattac tttgttcaac tccttatcct
    19321 agacgtggct tagttcaatc taagtatgtt ttatttgcaa tggtatttat ctattgtaca
    19381 ttagtttact ggattgaaaa tttacttatt ccacaaatag gaacttttga cttgacatat
    19441 attttgattg ttttattaat aagttctatt atttatggag tttatatgcc tattcaatac
    19501 aaattaggat atgaaacaac aaaattcttt ttcgtgatga taatcatggc ttcatcattt
    19561 gtattaccat taactatagc tcacagcaat tttgaaattc catttatata tcagtatcca
    19621 tccatgatag tgaatattgt attgttcctt ttaagtttaa ttatactgtt agcttcaatg
    19681 tttatttcta ttaaaatttt tagtaataag gagcttgtat aaggtaaggg ggacttttat
    19741 atgccacatt taccagattg ggctgtttta ctttgtatct tacttccaat agtatataaa
    19801 gcttgtcaga tatttaaaag taaaaaatag agtatatatt tatattgcca tttttattga
    19861 gtgaagttag atggtatgaa aaggttactt gaaaataaag ttacttggtg tgggagagta
    19921 acatcataat attatagatt atatgtttct tgtgaatcaa tttgtatttt ttaataggga
    19981 atatccagta attttgtttt ccattgatta tttttcaatt atgagtatga ttgtgtgtat
    20041 tgtataccat cttttaaggt gtttttaaaa aattatatcg tcaaaatata aatctaagga
    20101 atcctataaa taaagctttt taattttaga aaactaataa aaagtaggac gttaataaaa
    20161 agaagctgtc tcaaaataga gataagcttc tttttcattg ctgaaatgac gaaaatataa
    20221 ttgatttaat ataaaaaaga gtgctttatg aactatttat tttgaacagt agatacactt
    20281 gcactcaatt tagttactcc taagctttat gaactaaaag tttattttga agcttatttt
    20341 tattaaaaga gattttattt ttctaaataa tcatctatat acagtattgc gtttctttta
    20401 tttattcata atttattttc ttattaaagt ttttctatat tcatattttc tatattactt
    20461 tacttttaat tttatacgaa ttatcaaaaa taaaatagtt attagaaaaa aataaaagta
    20521 attgcaaagc ttgcaattac ttacttctat attaattact ataccataaa ataacaaaaa
    20581 aatcaagtcg agtaatcctt caacttaaat gatatactag gtattaataa tttttaatta
    20641 ataaaatata actagaggaa aatctacatt ttctcaattt ctttaattaa attgacctct
    20701 aattaagtaa ttataaggag aaaaattatg aatttagcaa agggattaga tgttttaaaa
    20761 atttcatcaa atgtattcgg tgaagataaa gttatgtata ttcctgtaat ctacacagaa
    20821 gatgatgcaa cacttattga cacaggtctt ccgggtcaag gtgatttaat aattgatgct
    20881 cttaataaaa gtaacacgag ctttgataag ttaaaaaata taataatcac tcatcatgat
    20941 atagaccata taggaaacat aaattatcta agagaaaaat ctaagaataa tatcaaagta
    21001 tatgcataca aaagtgaaat cagctatata acaggagaag aaactccttt taaactttat
    21061 atgttggaac aaatggtaga taaaattgat gataagatgc ttagtatgct aaatgttatg
    21121 ggacttggat ttaaatcatc atatactaaa gtagatgtgt cattagataa ccatgaaaaa
    21181 ttgaatctag gtgaggaaat agaagttata catacaggag gtcacactag aggtcacata
    21241 tgtctttatt taaaagagtc taaagtactt attgctggag atttgttaca ggtagaaaat
    21301 ggagaactta agcctgttga tgtgatgtac agcaacaaac aagagttaaa agatgctatt
    21361 aaaaatataa gtaattatga tatagaaacg atagttttta gtcatggtgg attatatcaa
    21421 agaaacataa ttggaacatt gaaaaaccta attattgagt agtactatat gatttacaat
    21481 aatttcttaa attacttaaa attatatcta aagatgtaga atcaaaatta aatataagta
    21541 ataagaattt tgctttaaaa ttatacttaa gtgttaaggg tgatatgtag tattacaagt
    21601 attttagaat ataatttttt atagtaattt taaagttcta caatacttca gttgaaaaat
    21661 atttaacagc atagtataat aggaaagaaa atattttaaa taaactttag tatacaaagt
    21721 gaagaaaaat atttaaatca tgtatcataa tgcaaagtaa agaaaatcat ttaaattata
    21781 tatcataaaa ataatatgaa gtattgaaca ctcataatat tagagacttt aatattttaa
    21841 ttgataggtt atattattta taacattaaa aatacaattt acataaaata gacatatgaa
    21901 aaataaaaaa ttatataata attatgggaa tgaggttctc ccttggatga taatatccta
    21961 aactgccaat gagctgatga cttctatgat atcatagatg ccaccagctt tttttgttgt
    22021 ttaaatcgat aaaatggagg tgaagtactt actaaatttt tattttttaa atttgaagaa
    22081 atatttaatt aatagaaaaa atagtagatt atatgttaat tattttatta agaatgggtt
    22141 aagagtgtac ctatatccta tcaatttaaa aaacaattat gatagtcatt acattgacta
    22201 cagttgatgt aataaaactt tcaaaaaatc ttatgatgca aatagaaagg aattaaaatg
    22261 atagaaaaat ttaaaacttt aatatggatt aaaatgataa taagaattaa aagcgtttat
    22321 aaaacatatg gtggactatt ttttttagga ctcataggta taccagttgg tgcaattata
    22381 ggtcttatag ataccatatt tggaacggtt cttctaaaag ttacagatat tcgagaaaca
    22441 tatccaatgt atctgatacc atttttagca gtagtaggag ttgttattgc ttattgctat
    22501 tttaaatttg gaggaaaaag tagtaaagga atgaatctaa tatttgaggt agggcatgga
    22561 gaagaagaaa ttattccttt aagattggtt ccatttataa tatcaggtac atggttaacc
    22621 catttatttg gtggtagtgc aggacgagaa ggagttgctg ttcagattgg tgcaactttt
    22681 tcacattggg taggtaaaag gttgcctata aaaaatgctt ctagtatttt tctagtaact
    22741 ggtatggcag ctggttttgc aggattattt gagacaccaa tagcagcaat actatttgct
    22801 atggaggttt tggttgctgg ttcactggag tatcaatcgc tttttcctgc gtttactgct
    22861 tcttttacag caagtgcagt atcaaaagct ttagggttag agaaattttc ttttgcactt
    22921 tcttctaaag ttgtatttga cttgtcaata ttttggaagc ttattgtttt aggaattatt
    22981 tttggaatgg ttggtggagc atttgcatgg tgtctgaaat tgtcaaaaag aaaaataggg
    23041 aatagattaa aaaatcctat gataaggatt gctattattg gagtatgtct tagtgtatta
    23101 ttccttttat tttataaagg aagatattca ggtttaggga caaatttaat tcaaaatagt
    23161 ttctatggtg gagaaattta ttcatttgac tggctgttaa agtttatact tacaatactg
    23221 actttgtcag caggttttca aggaggagag gttacacctt tgttttccat tggagctagt
    23281 cttggtgtat tgttagcagg attttttaat ttgccaattg aattagttgc agcgcttggc
    23341 tatgctagtg tctttggtag tgctacaaat actttttttg cacctgtatt tataggggca
    23401 gaagtttttg ggtacagcta tttaccttat ttctttgtag tatgcgctat ttcatatata
    23461 tttaatatgg ataaatctat ttattcacta caaaaaattt caacaaaaca ataaataaaa
    23521 caacataatg tatgattaga agagaaagaa tattagagaa aggatagggt aggaatatgt
    23581 tgacaagttt agctttgatt tttttattag gaatggcctc gggaggtatt tttaagagga
    23641 taaaattacc taacttattg ggaatgttac ttacgggaat tatattaggt ccatatgttt
    23701 taaatttgat tgataattca atactagata tttcttctga ccttagaaag attgcattga
    23761 ttattatatt aacaagggct ggattatctt tagatataaa cgatttgaag aaagtgggaa
    23821 gacccgctgt acttatgtgc tttattccag ctacttttga aattatcgga atgatagttt
    23881 tagcaccaaa gttactaggc gtttctatat tggaagcagc agtcatgggt gcagtagtag
    23941 gagcagtttc tcccgcaatt attgtaccta aaatgcttaa attaatggaa gaaggttatg
    24001 gtacagaaaa aagtattcca cagatgcttt tagcaggaac ttctatagac gatattttcg
    24061 taattgtgat gtttacagta ttcacaggat tggcacaagg aaatagtata tcagctatta
    24121 gctttttaca aattccagta tcaattatat taggtgtaat agttggagca gtgattggaa
    24181 tctatttagc agtatttttt aagaaggttc atatgagaga ttctgctaaa ggggtgttgc
    24241 ttttaagtat ctcattttta atgataagtt tagagactgc tttagagggt attgtgccat
    24301 tttctggatt attagcagtt atgagtattg ggattttcct tcagataaaa tatcgtgtag
    24361 ttgcaagaag attgtctata aagtattcga aactatgggt tggtgctgaa attctcttgt
    24421 ttgttttggt aggggcaaca gtagatataa gttatgcatt taaagcagga attggagctg
    24481 taattttaat atttggagtt cttttattcc gtatggtagg agtattcttc tgccttatta
    24541 agacaaattt gacaataaag gaaagattgt tctgtatgat tggctatatt ccaaaggcta
    24601 cagtacaggc ggcaatagga ggtgtaccac ttgcaatggg gatggcatct ggacaactta
    24661 ttttgacgtt agcagttcta gctatactta taactgcacc tcttggagct tttggaattg
    24721 atgtaactta taaaaaatta ttaacttctg taaaaggcga gaataagtaa aaataaagat
    24781 tattttaact ggtaagttat attttggaaa aggattatac tattgaatac aatataaaaa
    24841 aatcatttgg gagattaaga aggtagaagt taagaacaga ttttaaggta tgttatgatt
    24901 attagaattg attttgtgaa attattattg taatatttaa ttatatagat aaagaagcgg
    24961 agtgataact atgtgtttaa aaaaattatc aaaattagag ttagttatta tgaaatttat
    25021 ttggaattta gatataaaaa ccaattcata tgagattatt gattatatga aagaagaaca
    25081 taatttacca gaaaaagtag ctttaaaaac tttatcaaaa ctatcaaaga aaagattctt
    25141 atatgttcaa gaaacaggca agtgtatgta ttatacagtt gcaatcaaag aaaaggcata
    25201 tttagagttt atatcaagaa atgtgcaaaa tcttttgaag aataatttta taaggaattt
    25261 attagtatca tttcacgaag aggagctaac agaggaaaag ataaagtcgt tagaaaactg
    25321 ggtagtaaat tgggaagaag cttatgtata aatgttatta tttttattac aatttagata
    25381 attttggttt tgtaagctct gcaactattt ttagatggtt gcagagttta tttttatttt
    25441 ttattccctt aagcaatact taaaagtaaa cgcatttata tttactaact tcaattactt
    25501 ctaatactta aattgctttt taaaaatatt ttgatatgtc atctctatag taatctagaa
    25561 cttgtttcta ttctttatat aaagttttta tgaatgatat atataatatt cgttcatttg
    25621 attaaaaata acaaaatatt aaataattct actctgatag tttgttaaaa aaataataaa
    25681 aaatattaat aaacaaaaaa aaatatctta agagaggaga atgttctaaa atataaaaag
    25741 gtttctagat ttcataaaag atactatttt agtcttgaaa atatttagtt taaaaagatt
    25801 ttaatttaat gattgattaa gttaaaaatg tgtatgtaat aaa
//
LOCUS       DAMJVG010000056        25609 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.056, whole genome shotgun sequence.
ACCESSION   DAMJVG010000056 DAMJVG010000000
VERSION     DAMJVG010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 25609)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25609)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25609
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.056"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(<1..1000)
                     /locus_tag="PC512_002490"
     CDS             complement(<1..1000)
                     /locus_tag="PC512_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HDF2442225.1"
                     /translation="MKRVYIDFEMNMPNSKSKRAVFNSDIIAIGAVMYDEKTKNIDKF
                     KSLIRPVSNEELYPHIQELTHISSEELKSAPSYEEVMRKFKKWLGIFSDIKGIYTFGN
                     LDLTCFNNTDMRSAKKNNHPRFVNNIRDLFVDIKEKYINCGMRCMNYISLKNLLEFVN
                     LEFSGDAHDPLNDAYNLFILDEAITNNVDIQNLLIIRDIIRPPFNDINSNLDNCFNKF
                     KESLYKKEGNYNIVDFSVEIIKTVRMYLLTIIDVNIQNLEIMKDISKKMDTIDKLKDI
                     EEGYFYLLEDVYFDMKDVLEDLMLYRMNEDEYKYEIKNIIKMFDEDLDNEKIYINKC"
     gene            complement(1048..1908)
                     /locus_tag="PC512_002491"
     CDS             complement(1048..1908)
                     /locus_tag="PC512_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine(32) synthetase TtcA"
                     /protein_id="HDF2442226.1"
                     /translation="MSELSGKGCEIIVPFEERLPVRDIEKSIIKKYRKNLWSKFMKAI
                     RDYKLVEEGDKIAVAISGGKDSILMAKMFQELKKHGQVNFDVEFIAMDPGYHANIRQL
                     LIDNCEYLNIPIHLFDSRIFEIADEIAKDYPCYMCARMRRGALYSKAEELGCNKLALG
                     HHYDDVIETTMLNLLCAGNFKTMLPKLNSTNFEGIKIIRPLYYIREEHIIRFIQNSGI
                     WPLNCACMVAAKKTGNKRYEIKDLIKSLESNFKNVEKSIFKAAENVNLDSVLGWQKDG
                     EKHSFLENFE"
     gene            2177..2386
                     /locus_tag="PC512_002492"
     CDS             2177..2386
                     /locus_tag="PC512_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat associated protein CotJA"
                     /protein_id="HDF2442227.1"
                     /translation="MENKTRDIKKNCGPSLARPYINNQIFTEMYCLSDALKFGTIFPE
                     LNLLESEMYNKELYAKPKKYRGGRR"
     gene            2386..2652
                     /locus_tag="PC512_002493"
     CDS             2386..2652
                     /locus_tag="PC512_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein CotJB"
                     /protein_id="HDF2442228.1"
                     /translation="MKDSSRAELMRKVQETSFACVDMNLYLDNHPDDKNAINTYNSLC
                     NQFAQARYAYENKYGPLTNFGYAPSRCPWQWADQPWPWDREFNY"
     gene            2681..3253
                     /locus_tag="PC512_002494"
     CDS             2681..3253
                     /locus_tag="PC512_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000265278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HDF2442229.1"
                     /translation="MWIYQKTIQHPVNIKTCDPRMAKFLITQFGGPNGELAASLRYLS
                     QRYTMPTGNMRALLTDIGTEELAHVELICTMVYQLTSDASPEELKAAGLGSNYAQNGY
                     GIYPTDSNGVPFDVRPIAVMSNPVTDLHEDMAAEQKALATYYQLINLTDDVDVIDVLK
                     FLGQREIIHYQRFGEALMDAYELEESQKMF"
     gene            complement(3488..4678)
                     /locus_tag="PC512_002495"
     CDS             complement(3488..4678)
                     /locus_tag="PC512_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HDF2442230.1"
                     /translation="MNFNQKRIAASIMATAIIMPTMGNLAYANESEVESVSIESRTIT
                     GNAVNFRKGPGTNHESMGKLYKGDKVEYVGKEGSWVKVKYNGNTGYVHGNYVAINSLG
                     SSNESSDTSVKSTKVVTAKGLNFRTGPSTSSSKISTLGYGTEVGYISESNGWSKISSN
                     GRVGYVSSKYLGTSVNDSTNENAENSSNDLVKGTKVVTAKSLNVRTGPGTSHSKIATL
                     SYGTEVGSISESGGWTKISYGNQTGYVSSQYLAEKGSVDTSIPSYSTNSPSQGADSVI
                     SFAKTLLGKPYVWGAEGPNSFDCSGFTQYVMKKSVGVSIPRVSRDQSKYGTYVNRGDL
                     RSGDLVFFDTQGSNNGSVSHVGIYIGNGDMIHASSGSSKKVTISNINSSYYSSRYVNA
                     RRVL"
     gene            complement(4938..5369)
                     /gene="dut"
                     /locus_tag="PC512_002496"
     CDS             complement(4938..5369)
                     /gene="dut"
                     /locus_tag="PC512_002496"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HDF2442231.1"
                     /translation="MYNLKVKKLNDDAIIPNFAHKGDAGMDLYSIEEVVIPPGETKLI
                     KTGICIELPTMTEAQVRPRSGLALKHSVTVLNTPGTIDEGYRGELKIILINHGKNDFK
                     VEKHMKIAQMIVKPIYDINIEEVKELSDSERGKGGFGSTGF"
     gene            5482..7710
                     /locus_tag="PC512_002497"
     CDS             5482..7710
                     /locus_tag="PC512_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="HDF2442232.1"
                     /translation="MKLVLAEKPSVAKTIASFLGAKTRQDGYFEGNDYIITYAVGHLV
                     SLYDMKDYDKDKYSGSWKMNNFPFVPEDKFKFKIDSSKTKQFNTVKKLLNRKDVEYVI
                     NATDNDREGELIAFLIFLLAKNKKPVKRILVNEWTPEDITRGIKNLKDEDEMRNLQAA
                     GYTRLITDWLIGINFTSVATLKYGNGKLLNIGRVILPTVKLVYDRDMEILNFVPKTYY
                     EIEGHFKAEAGEYKGKYVKGKESKFDTLEDANKIIASITSETGKILDKKVTMSKEYAP
                     KLFSLTSLQGYITSKYSNFTSDKVLNVCQSLYEGNGKGGYITYPRTDSIFLEESLASK
                     ASQTLDKLKVGLEYENKIKFSKTKRVFDSSKVDSHSAIIPTYIIPKSLSKDEQLVYDA
                     IKDRFVANFMPPAEYENTEIKTEVDNCTFLTKGKVLKSKGYLEVYNKEEKNDLLPLVN
                     KDDVVDVLEIKPLTKQTTPPKPYTEDTLLKAMKNCGKNVPEEDTTVLSGYSIGTSATR
                     ADVLKKISQVGYVKKKGKSYSITDLGKNLVEIFPVKDLFDVDYTGKLEKSLSDIQKGK
                     YTRKEYLTNIISFIYQNVNIIKQDASKNINTEAYTFDSKTKKFTKTKEKKQKKDVTNT
                     EKEVAISKDSNNKKEVKNGDENQSLGKCPICQGDVLEFDKGFACKNHKECKFVIWKND
                     KYLSLYKKKVNKTMVKNILKKGETKVKSLTAKNGNKFDATLKYDKNPDTGYFNWKIEF
                     DN"
     gene            complement(7821..8306)
                     /locus_tag="PC512_002498"
     CDS             complement(7821..8306)
                     /locus_tag="PC512_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2442233.1"
                     /translation="MDNNNILKIADSFLDFLFVLENNIFKESDLLKKFQNNSDIMKAY
                     FEECPMAPSHAKVILYLMTSNSSSISQIASNLGILKSNMTPIIDRLVEHGLVNKFPDP
                     KDRRILRVELTDKAFKLFDAVKAILKESLVKKLSNLSEEELTLLDEHTLKLSEIVKKL
                     G"
     gene            8558..9781
                     /locus_tag="PC512_002499"
     CDS             8558..9781
                     /locus_tag="PC512_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HDF2442234.1"
                     /translation="MKRYLIVFLMCSSLFLVGCGKTEESEPEKPIAVSVQKAIGGEIE
                     NTNSFSGTTKVKDETAVTAQTVGTVQEVYVKLGQNVRKGDELLSISSPELENSVKQSK
                     ASLDLAKASYSSATGGSLEAQVNQAKTALDNAKIQYEESQRNYDNNKILYEQEVISLD
                     QFKKIEFSLEQTKQQLDSAQRAYDTATSKSIPQAKALAKKQLDQAQVSYNLAMSNLDK
                     LTLTSPVDGTITAKNFDSKEMITQSQPAFIISNPNILEVDLNVAESDIGKFKKDGNVD
                     VIIEDQRILGKIDYVPSVVDPQTSLYPVKVLVNNTNNKFKAGMSAQVNLSVEKENGAV
                     TVPKKAIFEENGKKYVYIATKDNIAKKHLVQTGIVTEDKIEIKSGVSDKDTVIIGGIS
                     LISDGTKIFPVEKEK"
     gene            9785..12919
                     /locus_tag="PC512_002500"
     CDS             9785..12919
                     /locus_tag="PC512_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HDF2442235.1"
                     /translation="MNLTQTSVKRPLTIIMVFLVLIVFGGIGYKKMSINLMPDIEIPV
                     VMVMTTWTGAGPQDVDEQVSQKVDESLSAVSNVKSTISSSQESVSMVVAQFEFGTNLD
                     EIMNDVRSKVDALQTSLPDDAAKPTVLKLDMNAQAIGQLVISGGNENSSQALRKYAED
                     VIQPKIESIDGVTSADLKGGEKAQVNVIADPAVLSNYGVSLSTIKGVLSSSNKTFPYG
                     SITQGEDKIVLRAIDKLESLDDIKQIQIPVKGGNTVRLDNLCSVDYGYADKDSIYRYN
                     GKDSLVIDISKQQDANTVKVMQSAYKYVDELNKENPQFKIKIANDTSSYISESINSVM
                     SNLLISAVIAFIVIFAFLKSVRASLVVAVAIPISIIGAIAILYFTGESLNLITASSLV
                     ISVGMVVDNATVVIENIFKYRKSGRLSLDDCAIEGTRTVTNAILASTLTTIAIFLPIM
                     FTEGIAKITFGALGKTLIASLAFSFIGAITLVPSVFAKLSRGKNSQKMQEKDSPIFDK
                     VSEAYKKLLSVCLRHQRLVVISSLLIFVASLFGMGFIGMDFMPAADKGELSISIELPK
                     GLSLESNDYYVSMTEKKVSDIPEIKTLITTLTSDSNNSKASIAIELESQKNRKRTTDE
                     IEKEIIDRVATVPDCKINVSQNSSVMGGAGGADFTLEMKGPDLDVLKILGKEAEKEFS
                     SIKGFRNVETSLTDTTQEAQFTIDKHKAQEYGVNTAEIAGMLRTAINGDSVTTATIDD
                     YKVDVNLKFKADTIDSLEDIKQLKVNSATGKEVPLGAFSDIKMADGLQSISRTDGDFS
                     VNITATLDNLDAGTATKLALEKTNKMVIPKDYSIGVGGETEMMNESMASLGFSMVIAI
                     ALVYMVMVAQFESFSKPFIIMFCVPFAFVGVVLSLLVSGQSLSTVGMLGIILLIGIVV
                     NNGIVLIDYIEQLRKTNRNNDLIGLVSIGCAARLRPVLMTTATTILGMLPTALSLGEG
                     GETMQPLAIVIMGGLTVSTLITLVLIPTIYLIFDKWENKFSDKMPKIFGKITDKIGSI
                     KRKIIKKPKLKAKV"
     gene            12953..14251
                     /locus_tag="PC512_002501"
     CDS             12953..14251
                     /locus_tag="PC512_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HDF2442236.1"
                     /translation="MSKIVAISCGVGIITANLIPVYADNNTSSINKVDNSILSDSNKR
                     TSEKEILTAREAVSAALKNSEKLKMKSEEIKMLKEKLEVQDEFDSFTGSDNSFPYDQI
                     GLLKNQSEQAKGFMEDQIANDITNKFNDLVSRENELDKIKNNLEIKTKEIKDMKLKKD
                     LGLVTSLETESAELELQTLQNTQKAKLQELKNNQDYFKLLTNIDLNNYQLDKEYRFES
                     FRVGGSVDSYMEGKVNEYLKYDQLILERTEESFNDKDENKADLPDRPNLTRPVAPTKP
                     EQGNLTDDEYKVLMDKYEKDYDRYKKEVEAYNLERQTYAAGLTTYANYLQQKFNTENG
                     LVTLEDSKKALKKGLIDSYAQLLALEDTIQITKKQLDLSEKQLKNTKLRYDLGLITLT
                     DYKKQVVSNEDAKNSYDTLIVNYNSLKNGIEKPWILNTGK"
     gene            complement(14540..14785)
                     /locus_tag="PC512_002502"
     CDS             complement(14540..14785)
                     /locus_tag="PC512_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HDF2442237.1"
                     /translation="MTKCPKCGKEVSSRPGSICPRCGFKVADESLKIRCPEPSCRALV
                     SRKLDYCPKCGCKLRGYNISEFVNMVRCKIDETFDKK"
     gene            complement(14999..17626)
                     /locus_tag="PC512_002503"
     CDS             complement(14999..17626)
                     /locus_tag="PC512_002503"
                     /EC_number="2.7.9.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, phosphate dikinase"
                     /protein_id="HDF2442238.1"
                     /translation="METKYVYSFGEGSKDMKSLLGGKGANLAEMTKIGLPVPPGFTIT
                     TEACNDYYVNNESIRAEIIKEIEEHLATLEKDLNKTLGCNKNPLLVSVRSGAVFSMPG
                     MMDTILNLGLNDNSVVGLAEATQNERFAYDSYRRFIQMFSDVAMEVPKYKFENVLDRV
                     KEAKGYTVDTELTTDDLKEIVKEFKAIYKKEIKNDFPQDPKEQLMLAIEAVFRSWNNP
                     RAIVYRKLNDIAHNLGTAVNIQSMVFGNMGETSGTGVAFTRNPATGENKLFGEFLMNA
                     QGEDVVAGIRTPQNISTLADVMPAVFDEFVKITHILEGHYKDMQDIEFTIENERLYIL
                     QTRNGKRTAAAAINVAVDLVEAGIIDEKEAIMRIEPNQLDQLLHPKFEDKALKEAKVI
                     AKGLPASPGAASGKVYFNADDVVKANEKGEKVVLVRLETSPEDIEGMVKAEGILTARG
                     GMTSHAAVVARGMGKCCVAGCGEIKVDEFNKEIRALDDVVIKEGEYISIDGSTGNVYL
                     GDVKKTEVSLTGNFEKLMNWVDKHKCMMVRTNADNPRDARAAIEFGAEGIGLCRTEHM
                     FFDEARLPAVREMILSNTVEQREKALEKILPMQREDFVELFKVMDGKPVNIRLLDPPL
                     HEFLPHDDETIEELSKSMGIKVSDIKKRIVDLDEFNPMLGHRGCRLAITYPEICVMQS
                     KAIIQGAIEAIKAGVKVSPEIMVPLVGEVNELKIIRKMIVETVDAIIKEEGIEVPYTV
                     GTMIEIPRACLTADEIAQEADFFSFGTNDLTQMAFGYSRDDAGKFLGQYVDEEILEKD
                     PFQVLDQNGVGKLVKMGAKLGREVKPELKLGICGEHGGEPSSVEFCYSVGLNYVSCSP
                     FRVPIARLAAAQASIKNPR"
     gene            complement(17687..18529)
                     /locus_tag="PC512_002504"
     CDS             complement(17687..18529)
                     /locus_tag="PC512_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HDF2442239.1"
                     /translation="MLVKNLIIYAVSDSVGETAQQVAKACMSQFYVNETYEIKRFPYM
                     INKGVLLETLENAKAENALIVYTLVDEELCSIVERYCEREGLSCIDLMTDILREISKR
                     TGRKPKREAGIIRKLDESYFKRVEAIEFAVKYDDGKDPRGVLQADIILVGISRTSKTP
                     LSMYLANKNIKVANVPLVPEIPIPKEVFEIDTKKIIGLTNSPEKLNEIRTQRLKALGL
                     SSKANYANLERILQELDYSEEIMKRIGCPVINVSNKAIEETAGIILDIMKENGLKIYK
                     EIEI"
     gene            complement(18536..19174)
                     /locus_tag="PC512_002505"
     CDS             complement(18536..19174)
                     /locus_tag="PC512_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2442240.1"
                     /translation="MIIIQLNERQLKIIDIVKENEPITSESIASSLNVTRATLRSDLA
                     ILTMTGILDARPKVGYFYSGVSEINLIGKSVKEKTVEDIMSMPVLAKKDESIYDVIVT
                     MFLSDVGSIVIIDENEELCGVVSRKDLLKATIGGSDINKMPIGMIMTRTPNVVTLTKG
                     ASVLLASRKIIEHEVDSIPIVEYKGEDKNHMRVVGRISKTNITKLFLEIVDN"
     gene            complement(19610..20902)
                     /locus_tag="PC512_002506"
     CDS             complement(19610..20902)
                     /locus_tag="PC512_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HDF2442241.1"
                     /translation="MLDLNRKLAKLEEEGKKIKVALIGAGHMGNGMVSQMANMKGIEA
                     SIVVDINLELAHKAFTDAGIDEEIIDNVTNEKDAEIKLQEGKVLTCNDFLVACKTKSI
                     DVVIDATGGIAIGAEIALNSILNKKHIVMLNAETDCVVGPILKKLADDAGVIFTGSAG
                     DEPGAVMELFDFADAMGFEVRVIGKGKNNKLDLDCNPDTVREEAERKGASPHMIASFK
                     EGTKTMVEMALMCNATGFVPDVRGGHGIEATVNEVPKKYALKSEGGVLDNYGVVDFVN
                     GIAPGVFVVVAHKLKAVNDELKYLSMGDGPNYILYRPYHLCSLETPLSAAMAVLDHKA
                     TIVPKAGLVAEVMTIAKKDLKKGEFMDGYGAYTCYGTIEKYDVAKAMNAVPIGLISKK
                     TKVVKDIKKGEVITYDMVEIEKDTTLYHLRQLQEKIFG"
     gene            complement(20939..21295)
                     /locus_tag="PC512_002507"
     CDS             complement(20939..21295)
                     /locus_tag="PC512_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HDF2442242.1"
                     /translation="MKYEVKISGIGSLVKELMDESNCLIIYDETINDDDLKDISVIHS
                     IATLKSDVEIGDTLTIGNRDYCIVSVGDIAQKTLREIGHCTIKFDGKCEVNLPGEIHV
                     EIGNPDITIGDLITIS"
     gene            complement(21330..21689)
                     /locus_tag="PC512_002508"
     CDS             complement(21330..21689)
                     /locus_tag="PC512_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442243.1"
                     /translation="MKLLVILFVAYILNTIFIMKQNKLYFKTLNRAKKKGDIVSTGKK
                     KSYFSKGSIAIISSDSDGFIKFGEILKGRTVMAKFKEIEEIEGLDIYSAEQKFKDEES
                     IVQAIKFIKEKINVSFN"
     gene            complement(21758..23731)
                     /locus_tag="PC512_002509"
     CDS             complement(21758..23731)
                     /locus_tag="PC512_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HDF2442244.1"
                     /translation="MSVTEKIPSIDRKIFKILIMCSKKEFVSINSIANELNVTTRSVR
                     TYIKQLNKDLGNDIAVIKYIKGQGYKLEIKDEQILNKIIDMNRKNVFSLNSKEDRVEF
                     ILNYLIELDGFITLDSLADEMCVGRTTLVNDFQYVEKVLASYNLNLIKKQNTGMKLNG
                     NELDIRLFILNQLYKNSRKDFSNSKYFKGIKKEEIINLEEKLLTLFKKNNFYVTDEML
                     REVINYIVVLVYRVKEEKKVKDYDVKFDLLKSYDEYFIAREIKHIISGMFECTLNDEE
                     IIYLTIPLVSGNAPASECALNSSRISKNIDELMENIFNQIYVDMGIFINEDELRVGLG
                     YHLSFTLNRLLFNIKLKNVLLEEIKQNYILPFKLAQIAGKVIEKKYNLEVSEDEIGYI
                     AIHFSGYLERNSSRFYSIKKIAIICSTGLGTAKLLKIRVEKLIGNNPKIDTLSSFNLR
                     NINLDEYDIVFTTIDLDTSNINTIVLKINTIFDENKLREQLKTVLCLREGNIDTTNST
                     NLLINNLLDEDKFMILNEKTILASLEKMMDHLMDLGCIDDKFRKNIVNREEKSPTVFD
                     KGLLFPHSVNEKSDKFLMAVGILEEPIEYANRSIKIILMTMFPCENKIDSDLLVKIYE
                     EVLKIGQDVKLTNKISKCRTFLEFKKVLLKNLI"
     gene            complement(23953..24966)
                     /locus_tag="PC512_002510"
     CDS             complement(23953..24966)
                     /locus_tag="PC512_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HDF2442245.1"
                     /translation="MEENKILKIEKGTSGWGGPLYIKKEGNRNKILSMTAGGIHEVTL
                     KIKELLGCEIVDGFKTGVSDEEVAVVIIDCGGTARCGVYPKKKIPTINVNPVGKTGPL
                     AKFITEEYYVSDVNPNCISVVDGEDMPQKSQENKSENKSSIRKPDNYDEVKSKAQGEY
                     AKKNIILSIGQGAGQVVSKFYDAGRDTIQMVMNNVIPFMAFVSMLMGIILASGLGDWI
                     ARVISPLAGNIGGLLIISVICTLPFLSPILGPGAVIAQVVGTLVGTQIGLGAIPAYLA
                     LPALFAINGQAGCDFVPVGLSLGEAEPETVEYGVPALFYSRLITGPIAVIIAYGVAVF
                     ALR"
     gene            complement(24979..25524)
                     /locus_tag="PC512_002511"
     CDS             complement(24979..25524)
                     /locus_tag="PC512_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HDF2442246.1"
                     /translation="MENVITGLSKGAEWFIGLFQKGGEQFIGLVSGTLPTLIVLMVAI
                     NSLIKIIGEERVNNWASKLGKNSFTRYILLPLVSVFFLGNPMCYTFGRFLKEEHKAGF
                     YDAAVSFVHPITGLFPHANAGELFVWLGISAGLTTLGKETTTLALWYFIVGLIVIFIR
                     GIVTEKMYAFLTRKNRATNKA"
BASE COUNT         8762 a         4268 c         3257 g         9322 t
ORIGIN      
        1 tacatttatt tatatatatt ttttcattat ctaagtcttc atcaaacatt tttattatat
       61 tttttatctc atacttgtac tcatcttcat tcattctata aagcattaaa tcttctagta
      121 catctttcat atcgaagtac acatcttcta ataaataaaa atagccttcc tctatatctt
      181 tcaatttatc tatagtatcc atttttttac ttatatcttt cataatttct aaattttgta
      241 tatttacatc tatgattgtt aataagtaca ttctcacagt ttttattatt tcaacagaaa
      301 aatctacaat attataattt ccttcttttt tatataatga ctccttaaat ttgttaaaac
      361 aattatctaa attagaattt atatcgttaa atggtggtct tattatgtca cgtattatta
      421 aaagattttg tatatctaca ttatttgtga ttgcctcatc caaaataaat aaattatatg
      481 catcatttaa tgggtcatgg gcatctccac taaactctaa gttaacaaat tcaagtaaat
      541 ttttcaatga tatatagttc atacatctca taccacaatt tatatatttt tcttttatat
      601 ctacaaataa atctctaatg ttatttacaa accttggatg gttatttttt ttagcacttc
      661 tcatatctgt gttattgaaa catgtcaaat ccaaattacc aaaagtatat attcctttaa
      721 tatcagaaaa tatgccaagc cattttttaa actttctcat gacctcttca taacttggtg
      781 cactcttcaa ttcttcagaa gatatatgtg ttaattcttg tatatgagga tacaactcct
      841 cattacttac tggtcttatt aaagatttaa atttatcaat attttttgtt ttttcatcat
      901 acataactgc tccgattgca attatatcag aattaaatac tgctcttttt gatttagaat
      961 ttggcatatt catttcaaaa tctatatata ctcttttcaa tataaacacc ctttccaatt
     1021 gtttatagtg attcttttta actattttta ttcaaaattt tctaagaaag aatgtttctc
     1081 cccatctttt tgccaaccaa gtactgaatc aagatttaca ttttctgccg ccttaaatat
     1141 agatttttct acatttttaa aatttgattc taagctcttt attaagtctt ttatctcata
     1201 tcttttatta cctgtttttt tagcagcaac catacatgca caatttaatg gccatatacc
     1261 actattttga ataaatctta taatatgttc ttctcttata taataaagtg gtcttataat
     1321 ttttatacct tcaaaattag tagaattaag tttaggaagc attgttttaa aatttccagc
     1381 acacaataaa ttaagcattg ttgtctctat tacatcgtca taatgatgac ctaatgcaag
     1441 tttgttacac cctaattctt ctgcctttga atataatgct cctctcctca ttcttgcaca
     1501 catatagcat ggataatctt ttgctatttc atctgctatc tcaaatatcc ttgaatcaaa
     1561 taaatgtatt ggtatattta gatactcaca attatctata agtaattgtc ttatatttgc
     1621 atgatatcca gggtccatag caataaattc aacatcaaaa ttaacttgtc catgtttttt
     1681 taactcttga aacattttag ccataagaat actgtctttt ccaccagaaa tcgctacagc
     1741 tatcttatca ccttcttcaa ccaatttata atctcttatt gccttcataa acttagacca
     1801 taaatttttc ctatattttt ttattatact tttttctata tctcttactg gaagtctttc
     1861 ctcaaaagga actataattt cacagccttt tcctgatagt tcactcatct aatcacctcg
     1921 tatatttatg ttaataatat tttacaaaaa agtctacctt catccacaaa atactataat
     1981 ttttacttta attttactaa ataatttata gtttacaata acacataaac ttataataac
     2041 ataaataacc tctttctttt attatctttt ttatttttct catttaatat tttattatta
     2101 gtaacgattt ttaaatgatt gaatattata cactagatag agttacctat ctatttacaa
     2161 caaggaggtt ttcatcttgg aaaataagac tagagatatc aaaaaaaatt gtggtccatc
     2221 tttggctaga ccatacatta ataatcaaat tttcacagaa atgtactgcc tttctgatgc
     2281 attaaaattt ggaactatat ttccagaact aaacttacta gagtctgaaa tgtacaacaa
     2341 agaattatat gctaagccaa aaaaatatag aggaggtaga agataatgaa agactcatct
     2401 agagctgaac ttatgagaaa agttcaggaa acatcttttg catgtgttga tatgaactta
     2461 tatttagaca atcaccctga tgataaaaat gctatcaaca cttataattc attatgtaat
     2521 caatttgcgc aagctagata tgcttacgaa aataaatacg gtcctttaac taactttggg
     2581 tatgctccaa gtagatgccc ttggcaatgg gctgaccaac cttggccttg ggacagagaa
     2641 tttaattatt agacatcaag tattggagga ttgaaaattc atgtggatat atcagaaaac
     2701 tatacaacac ccagttaata taaaaacttg tgaccctaga atggctaaat ttcttataac
     2761 tcaatttggt gggccaaatg gagaacttgc tgcatcttta agatatttaa gccaaagata
     2821 tacaatgcct actggtaata tgcgtgcact tttaacagat attggtacag aagaactagc
     2881 tcacgttgag cttatatgta ctatggttta tcagttaact tctgatgcaa gcccagaaga
     2941 gttaaaagct gcaggtcttg gttcaaacta tgctcaaaat ggatatggaa tttatccaac
     3001 agattcaaat ggtgttccat ttgatgtaag acctatagca gttatgtcaa atcccgtaac
     3061 cgatttacat gaggatatgg cagctgaaca aaaagcactt gcaacttatt atcaacttat
     3121 aaacctaaca gatgacgttg atgttataga tgtattaaaa ttcttgggtc aaagagaaat
     3181 aattcattat caaagatttg gtgaagcctt aatggatgct tacgagttag aagaatctca
     3241 aaaaatgttc taaaattttt atttgtataa ctattattat ttgataattt ataatttact
     3301 gttgtgttaa aatttataaa aaatataaat ataatttatt ttctataaac agagaaaata
     3361 aataaaaagc aggtatcaat caaatagtaa catgtattat actatacatt actatcaata
     3421 ttgtacctgc tttcatatta taagcaataa agaaaaatct atttattagg ttttataata
     3481 aaaacaatta taaaactctt cttgcattta catatctact tgaatagtag ctactattta
     3541 tattagatat tgttactttt tttgatgaac ctgaagatgc atgtatcata tctccatttc
     3601 ctatgtatat tccaacatga cttacagaac cattatttga accttgtgta tcaaagaata
     3661 ctaaatctcc acttctaagg tctcctctat ttacatatgt tccatactta ctttggtctc
     3721 tagatactct tggtatacta actcctacag attttttcat aacgtactgc gtgaatccag
     3781 aacagtcaaa actatttgga ccttctgctc cccatacata tggttttcca agtagtgtct
     3841 ttgcaaaact tattacacta tcagctcctt gacttggaga attagtcgaa taagatggaa
     3901 ttgaagtatc aacagaacct ttttcagcaa ggtattgact tgacacatat ccagtttgat
     3961 tgccataact tatttttgtc catcctccac tttcagaaat acttccaacc tcagtaccat
     4021 aacttaatgt agctatttta gaatgacttg tacctggtcc tgttctaacg ttcaatgact
     4081 ttgctgttac aacctttgta ccctttacaa ggtcatttga actgttttca gcattttcat
     4141 ttgtagagtc atttacacta gttcctaaat atttacttga aacataacct actctaccat
     4201 tagaacttat ttttgaccat ccatttgact cagatatgta tccgacttca gtcccatatc
     4261 ctagtgttga tattttagaa ctacttgtac ttggtcctgt tctaaaattt aatccttttg
     4321 ctgttacaac ttttgtcgac ttaactgaag tatcactact ttcattgcta cttccaaggc
     4381 tatttattgc tacataattt ccatgcacat aacctgtgtt tccattatat ttaactttta
     4441 cccaagaacc ttcttttcct acgtactcaa ctttatcacc tttgtaaagt ttccccattg
     4501 attcatggtt tgtacctggt ccttttctaa aatttaccgc attccctgtt attgttctgc
     4561 tttctatact cacactctct acttcagact cattagcata tgctaaattc cccatagtag
     4621 gcattattat cgcagttgcc attatactgg ctgctattct cttttgatta aaattcataa
     4681 ctttccactc atctcctctt ttctactatc tttatttcac ttcaaaatat aaaagaaata
     4741 attgacacta tcaaaatatc aattatttct tttatattaa tattattaca aatttgtaac
     4801 tatttgtcta tagtaatatt tgcttaccat aaattaccat gtataaattt taatctttaa
     4861 tagcctgtaa tttagtaata tagccatctt ttaccttttt taaaaatggc tatatttttt
     4921 aacttttttg taacttttta aaatccagtt gagccaaacc caccttttcc tctttcggag
     4981 tcacttaatt cttttacttc ttctatgtta atatcataga taggttttac tatcatttga
     5041 gcaattttca tatgcttttc aaccttaaaa tcatttttac catgatttat taatataatt
     5101 ttaagctctc ctctgtatcc ttcgtcaata gttcctggtg tatttaatac agtaacagaa
     5161 tgctttaagg caagcccact tctaggtctt acctgcgctt ctgtcatagt aggaagctct
     5221 atacatatcc cagttttgat aagtttagtc tctccaggag gtattacaac ctcttctata
     5281 gaatacaaat ccataccagc atcacctttg tgagcaaaat taggtattat agcatcatca
     5341 tttaattttt ttacttttaa attgtacatc ttatatctcc tttcaacttt ctataaatat
     5401 tataacttaa atttcgacct cttgaagttt tttatttttt tgtggtaata taattattag
     5461 tgttttaaag gaggattttt tatgaaactt gtacttgctg agaaaccatc tgtggcaaaa
     5521 actatagcat catttttagg tgcaaagacc agacaagatg gttactttga aggaaatgat
     5581 tatataatta cttatgcagt tggacactta gtatcattat atgatatgaa ggattatgat
     5641 aaagataaat actctggctc ttggaaaatg aacaatttcc catttgttcc tgaggataag
     5701 tttaaattta agattgatag ttctaaaact aaacaattca acactgtaaa aaagcttttg
     5761 aatagaaaag atgtagaata tgtaataaat gccactgata atgaccgaga aggagaactt
     5821 atagcatttt taatattttt actggcaaaa aataaaaaac cagtaaaaag aatcttggta
     5881 aatgaatgga caccagaaga tattacaaga ggtataaaaa acctaaaaga tgaagatgaa
     5941 atgagaaatc ttcaagctgc tggatatact aggcttatta ctgactggtt gattggaata
     6001 aatttcactt ctgttgctac attgaaatac ggaaatggga aactattaaa cataggtagg
     6061 gtaattcttc caacagttaa attagtctat gatagagata tggaaatact aaactttgtt
     6121 cctaaaactt attatgaaat agaagggcat tttaaagctg aagctggtga atataaaggt
     6181 aaatatgtta agggtaaaga aagtaaattt gatacacttg aagatgcaaa taaaattata
     6241 gcttcaatta catctgaaac tggtaaaata ctagataaaa aagttactat gtcaaaggaa
     6301 tatgcaccaa aactttttag tttgacatca cttcaaggat atataacttc taagtattcc
     6361 aattttacat ctgataaggt tttaaatgtc tgtcaatctc tctatgaggg taatggtaag
     6421 ggtggataca taacttaccc tagaactgat tccattttct tagaagaaag tttggcttca
     6481 aaagcttctc aaactttaga taaattaaag gttggtcttg aatatgaaaa taaaattaaa
     6541 ttttctaaaa ctaaaagagt ttttgattct tctaaagtag actcccatag tgctataatt
     6601 ccaacttata taattccaaa aagtttatct aaggatgaac aattagttta tgatgccata
     6661 aaagatagat ttgtagcaaa ctttatgcct cctgctgaat atgagaatac agaaattaag
     6721 actgaagtag ataattgtac tttcttaaca aaaggtaagg tgcttaaatc aaaaggatac
     6781 cttgaggtat ataataagga agaaaaaaac gatttacttc cacttgtaaa taaagatgat
     6841 gttgtagatg tgttagaaat aaaaccatta actaagcaaa ctactccacc taaaccgtat
     6901 actgaggaca cacttttaaa ggctatgaaa aattgtggta aaaatgtgcc tgaagaagat
     6961 acaacagtgc tatctggata ttcgattgga acatcagcca cacgtgctga tgtgttaaag
     7021 aagataagtc aagtgggcta tgtaaagaaa aaaggtaaat cttattctat aacagacctt
     7081 gggaaaaatt tagttgaaat ttttcctgtt aaagacttat ttgatgtaga ttatactgga
     7141 aaacttgaaa aaagtttaag cgatattcaa aaaggaaagt atacaagaaa agaatatctt
     7201 actaatatca ttagttttat atatcaaaat gtcaatatta taaaacaaga tgcttcaaaa
     7261 aatataaaca cagaagcata tactttcgat tcaaaaacta aaaaatttac taaaacaaaa
     7321 gaaaaaaaac agaaaaaaga tgtaactaat actgaaaaag aagttgctat atcaaaggat
     7381 tctaataaca aaaaagaagt taaaaatggt gatgaaaatc aatctcttgg caaatgcccc
     7441 atttgtcaag gtgatgtact agaatttgac aaaggctttg cttgtaaaaa tcataaagaa
     7501 tgtaaatttg ttatttggaa aaatgataag tatttaagtc tttataaaaa gaaagttaac
     7561 aaaacaatgg tcaaaaatat tttaaaaaaa ggtgaaacta aagtaaaatc tttaactgct
     7621 aaaaacggta ataaatttga tgctacatta aaatatgata aaaatccaga tactggctat
     7681 ttcaattgga aaatagagtt tgacaactaa atattcataa gaaaagaaat agcagtagta
     7741 taataatcta tattatatta ctgctatttc ttttcttatg aagtttcaac ttttttaata
     7801 gtgactttta caatcacact ctaacctaat ttctttacta tttctgataa ctttaatgta
     7861 tgttcatcta ataaagttag ttcctcttca gaaagattag ataatttttt tactagagat
     7921 tctttgagaa tagcttttac tgcatcaaat aatttaaatg ctttatctgt taattcaacc
     7981 ctaagaatcc ttctatcttt tgggtcagga aatttattga ctaaaccatg ttccactaat
     8041 ctgtcaataa tcggagtcat atttgatttt aaaattccta aattagaagc tatttgagaa
     8101 attgatgatg aatttgatgt cataagataa agaattacct tagcatgtga tggagccatt
     8161 ggacattctt caaaataagc tttcattata tcagagttat tttgaaactt ttttaacaaa
     8221 tcgctttctt taaatatatt attttcaagc acaaataaaa aatctaaaaa agagtccgct
     8281 attttaagta tattgttgtt atccatattt gtaacatccc ttcaatagat aatataataa
     8341 aacattgttg tttaatatag tataaattat aaactattaa taaatttaaa acaagaaaaa
     8401 gttattgact cataataatt ataaatttat aatcaaatta gagaattata aattgccaat
     8461 aaagggaagt tttttaatta gtctaaaact aaacttaaat tataagacac tttaaattct
     8521 acaacaagct agtgtgcaat atataatagg aggagatatg aaaagatatt taatagtttt
     8581 cttaatgtgt agttcactgt ttttagttgg atgtggaaaa acagaagaat ctgaacctga
     8641 gaaaccaata gcagtttctg ttcaaaaagc aataggtgga gaaattgaaa acacaaattc
     8701 tttctcagga actacaaagg ttaaagatga aacagctgtt actgcacaga ctgttggcac
     8761 agttcaagaa gtgtatgtaa aacttgggca aaatgtaaga aaaggagatg aattattgag
     8821 tataagcagt ccagagctag aaaatagtgt aaagcaaagt aaagcctcac tagatttagc
     8881 aaaagcaagt tattcaagtg ccactggtgg ttcattagag gcacaagtaa atcaggcaaa
     8941 aacagctctt gacaatgcaa agattcaata tgaggagtct caaagaaatt atgacaataa
     9001 taagattctt tatgaacagg aagtcattag tttagaccaa tttaaaaaaa tagaattttc
     9061 tttagagcaa acaaaacaac agttagattc tgctcaaaga gcatacgata cagcaacttc
     9121 aaaaagtata cctcaagcta aagcacttgc taaaaaacag cttgaccaag ctcaagtatc
     9181 atataattta gcaatgagta atttagacaa attaacatta acatctccag tagatggtac
     9241 aataacagct aaaaactttg attcaaagga aatgataaca caatcacaac cagcttttat
     9301 tatttctaat cctaatatac tagaagttga tttaaatgta gcagaatcag atataggtaa
     9361 atttaagaaa gatggaaatg tagatgttat aattgaagac caaaggattt taggaaaaat
     9421 agattatgta ccttcagtag ttgaccctca gacatcttta tatcctgtta aagtacttgt
     9481 aaataataca aacaacaaat ttaaggcagg tatgtctgct caagtaaact taagtgttga
     9541 aaaagaaaat ggtgctgtta cagtacctaa aaaagcaata tttgaagaaa atggtaaaaa
     9601 atatgtatac atagcaacaa aagacaatat agcaaagaaa cacttggttc aaactggaat
     9661 tgtaacagag gataaaatag aaattaaaag tggtgtaagt gataaagata cagtgattat
     9721 cggagggata agtcttattt ctgacggaac taagatattt cctgtagaaa aggagaagta
     9781 gactatgaat ttaacacaga cttccgttaa acgtcctctc acaatcataa tggtcttttt
     9841 agtattaata gtttttggtg gtattggata taaaaaaatg tcaataaatc taatgcctga
     9901 tatagaaata ccagttgtaa tggtcatgac tacttggaca ggtgctggtc ctcaagacgt
     9961 tgatgaacaa gttagtcaaa aagttgatga aagtttatct gccgtttcaa atgtaaaatc
    10021 tactatatca agttcacaag aaagtgtttc tatggtagtt gctcagtttg aatttggaac
    10081 taatttggat gaaataatga atgatgttag gtctaaagtt gatgcattac agaccagcct
    10141 cccagatgat gcagctaaac caacagtttt aaagctggat atgaatgcac aggctatagg
    10201 tcaacttgtc atatctggag gaaatgaaaa tagttcacaa gccttaagaa aatacgctga
    10261 agatgtaatt cagcctaaaa tagaatccat agatggtgtt acttcagcag accttaaagg
    10321 tggagaaaaa gcacaggtta atgtaatagc tgacccagct gttctttcaa attatggagt
    10381 tagtttatcc actataaaag gtgtcttatc ctctagtaat aaaacattcc cttatggttc
    10441 aattactcaa ggtgaggata aaatagtttt aagagcgatt gataaattag aatccctaga
    10501 tgatataaaa cagattcaaa ttcctgtaaa aggaggaaat acagttagat tagataatct
    10561 ttgtagtgta gattatggat atgcagacaa agatagtatt tatagataca atggaaaaga
    10621 cagtttggta atagatattt ctaaacaaca agatgccaac actgtaaaag ttatgcagag
    10681 tgcatacaaa tacgtagatg aattgaataa ggaaaatcct caatttaaaa ttaaaattgc
    10741 taatgataca agttcataca taagtgaatc aataaacagt gtaatgagca acttgcttat
    10801 aagtgctgtt atcgcattta ttgtaatatt tgctttccta aaaagtgtaa gagcttcact
    10861 agttgttgca gttgcaatac caatttctat aataggtgct atagcaattc tctactttac
    10921 tggtgaaagt ttaaatctta ttactgcaag ttcattggta atttcagttg gtatggttgt
    10981 tgataatgct acagttgtaa ttgaaaatat atttaaatat aggaaaagtg gtagattgag
    11041 tcttgatgat tgtgctattg agggaacaag aactgtaaca aatgcaatac ttgcatcaac
    11101 attgaccaca atagcaatat tcttacctat catgtttaca gaaggtatag ctaaaataac
    11161 ttttggggca ttaggtaaaa cactaatagc ttcactagca ttctccttta taggtgcaat
    11221 tacactcgtt cctagtgtat ttgcaaaatt aagcagagga aaaaatagtc aaaagatgca
    11281 agaaaaagat agtcctatat ttgataaggt aagtgaagca tataaaaaat tattaagtgt
    11341 atgtttgaga catcaacgct tagttgtaat atcaagttta cttatttttg tagcttcctt
    11401 atttggaatg ggatttatag gtatggactt tatgcctgca gcagacaagg gtgaattatc
    11461 tatttctata gaacttccaa aaggtcttag cctagaatcc aatgattact atgtatctat
    11521 gactgagaaa aaagtctcag atattccaga aattaaaact ttaataacaa ctttgacatc
    11581 agattcaaat aatagtaaag caagtatagc aattgaatta gaatctcaaa aaaatagaaa
    11641 aagaactact gatgaaatag aaaaagagat aattgataga gtggctactg taccagattg
    11701 taaaataaat gtaagtcaaa acagtagtgt tatgggtgga gctggaggag cagacttcac
    11761 attagaaatg aaaggtcctg atttagatgt attaaaaata ctgggaaaag aagctgaaaa
    11821 agaatttagc tctataaaag gatttagaaa tgttgaaact tctcttacag atacaacaca
    11881 agaagctcaa tttactatag ataaacataa ggctcaagaa tatggtgtaa ataccgctga
    11941 aattgcaggc atgttacgta cagcaataaa tggtgactcc gtaaccactg ctactattga
    12001 tgattacaaa gtggatgtaa acctaaaatt taaagcagat actattgata gcttagaaga
    12061 tataaagcaa ctaaaagtaa actctgcaac tggaaaagaa gttcctcttg gtgccttttc
    12121 agatataaaa atggcagatg gtctacaatc tatatctagg actgatggag atttttctgt
    12181 aaatataact gctacacttg acaatttaga tgctggtact gctacaaaac tagcactaga
    12241 aaaaacgaat aaaatggtaa ttcctaaaga ttactctata ggtgttggtg gtgaaacaga
    12301 aatgatgaat gaatctatgg caagtcttgg attttcaatg gtcatagcta tagcattagt
    12361 ttatatggta atggtagctc agtttgaatc atttagtaaa ccatttataa tcatgttctg
    12421 tgttccattt gcattcgttg gagttgtgct ttcgcttcta gttagtggtc aaagtttaag
    12481 tactgtcggt atgctaggta taatcttact tatcggtatt gttgttaata atggtatagt
    12541 tcttattgac tacatagagc aacttagaaa aacaaatcgt aacaatgatt taattggttt
    12601 ggtttcaatt ggttgtgcag caagattaag accagtctta atgactacag caacaacaat
    12661 tttaggtatg ttgccaacag cactatctct tggtgaaggt ggagaaacta tgcaaccact
    12721 agccatagtt ataatgggtg gtctaactgt atctacactt ataactttgg tgcttatacc
    12781 tactatatac ttaatatttg ataaatggga aaataagttt tcagacaaaa tgcctaaaat
    12841 atttggtaag ataacagata aaataggaag tataaaacgt aaaataataa agaaaccaaa
    12901 attgaaagct aaagtttaaa tagaatggag ggtgattgta ttgaataaaa aaatgagcaa
    12961 aatagttgca attagctgtg gtgttggtat aataactgcc aatttaatcc cagtttacgc
    13021 agataataat acttcttcta taaacaaagt tgataattct attttaagtg actcaaataa
    13081 aagaacatct gaaaaggaaa ttttgactgc tagagaagct gttagtgctg cacttaaaaa
    13141 tagtgaaaaa ttaaaaatga aatcagaaga aataaaaatg ttaaaagaaa agttagaagt
    13201 acaagatgag tttgatagtt ttactggaag tgacaactcg tttccatacg accaaattgg
    13261 acttcttaaa aatcaaagtg aacaggctaa aggctttatg gaggaccaaa tagcaaatga
    13321 tattactaat aaatttaacg atttagtttc aagagaaaat gagctagata aaataaaaaa
    13381 caatcttgaa ataaaaacta aagaaattaa agatatgaaa ttaaaaaaag atttagggtt
    13441 agtaacatct ttagaaactg aatcagctga acttgaactt caaacactac aaaatactca
    13501 aaaagctaaa cttcaagaac taaaaaacaa tcaagactat tttaagttat taactaatat
    13561 agatttaaat aattatcaat tggataaaga atatagattt gaatctttta gagtaggtgg
    13621 ctcagttgat tcatatatgg aaggtaaggt taatgaatat ttaaaatacg accaattgat
    13681 tttagaacgt acagaagaaa gctttaatga taaagatgag aacaaagcag atttaccaga
    13741 tagacctaac cttacaagac cagttgctcc tacaaaacca gagcaaggta acctaactga
    13801 tgatgaatac aaggttctta tggataagta tgaaaaagat tatgatagat ataaaaaaga
    13861 agttgaagca tacaatcttg aaagacagac ttatgctgct ggccttacta cttatgcaaa
    13921 ttatcttcaa caaaaattta atactgaaaa tggtctagta acattagaag acagtaaaaa
    13981 agctcttaaa aaagggttaa ttgatagcta tgctcaatta cttgctttag aagatacaat
    14041 tcagattact aaaaaacaac ttgatttatc agaaaaacaa ttaaaaaata ctaaattaag
    14101 atatgattta ggattaatta ctctaactga ttataaaaaa caagtggtaa gtaatgaaga
    14161 tgctaaaaat agctatgaca ctcttattgt gaattataac tcactaaaaa atggtataga
    14221 aaaaccttgg atacttaata ctggaaaata attctggtaa atagaaagat tactttaaca
    14281 tacgtttgat taaaaaatag ttatgcatac tcgtggcttt agtcatggaa gattcagaag
    14341 gcaaataata gaaatagatt agtaaaaata tatttactta taaaactgta tacttttata
    14401 gaggctatct caaaatagag ataagcctct tttttattgt ttaaattata aaaatatatt
    14461 tgattccata caaaaagagt gccttctgaa ctaaaaagtt cattttgaga caccctcaaa
    14521 agcttaactc taaatttaat tattttttat caaatgtttc atctatttta catctcacca
    14581 tgttaacaaa ttcagaaata ttatatcctc taagtttgca tccacattta ggacaataat
    14641 ccagtttcct agataccaaa gccctacaac taggttctgg acatcttatt tttagactct
    14701 catctgctac tttaaatcca catcgtgggc atatactacc tggacgtgat gatacttcct
    14761 ttccacattt aggacacttt gtcaacttta tcccctccag taaactcaat ttaattgata
    14821 gttgaaattt ctctctacaa taatatatgc aatataatta aatacgtttc acttacaact
    14881 atataagtta aatttttata ataaaaatcc cctatattca atttacaaat acttaatttg
    14941 atacattgaa caatagggga ttttattttt atttagttac atattttgca gtctattatt
    15001 atctaggatt ttttatagat gcttgagctg ctgcaagtct agcaattggc actctaaatg
    15061 gtgaacaaga tacatagtta agtcctacac tataacagaa ctctactgaa gatggttctc
    15121 ctccatgctc tccacatatt cctagtttta attctggttt aacttctcta cctaatttag
    15181 ctcccatctt aactaactta ccaacaccat tttggtctag tacttggaat gggtcttttt
    15241 ctaatatttc ttcatctaca tattgaccta agaatttacc agcatcatct cttgaatatc
    15301 caaatgccat ttgagttaag tcattagtac caaaactgaa gaagtctgct tcttgtgcta
    15361 tttcatcagc agttaaacaa gctctaggta tttctatcat agtacctaca gtataaggaa
    15421 cttctatacc ttcttctttt attatagcgt caacagtttc tactatcatt tttcttatta
    15481 tttttaactc atttacttct ccaactaatg gaaccattat ctctggagaa actttaacac
    15541 ctgctttgat tgcttctata gcaccttgta ttatagcttt agattgcatt acacatattt
    15601 caggataagt tattgcaagt ctacaacctc tgtgtccaag cattgggtta aactcatcta
    15661 aatcaactat tctcttctta atatcactta cttttattcc catagatttt gaaagttctt
    15721 ctatagtctc atcatcatga ggcaaaaatt catgtagtgg tgggtctagt aatcttatat
    15781 taactggttt tccatccata actttaaata actctacaaa atcctctctt tgcattggta
    15841 atattttttc aagagctttt tctctttgtt ctactgtatt agataatatc atttctctaa
    15901 ctgctggcaa tctagcttca tcaaagaaca tatgctcagt tctacataga cctatacctt
    15961 ctgcaccaaa ctctatagct gcacgagcat ctctaggatt atctgcatta gttctaacca
    16021 tcatacattt gtgtttgtct acccagttca ttaatttttc aaaatttcca gttaaagata
    16081 cttctgtttt cttaacatct cctaggtaca catttcctgt agaaccatct atagaaatgt
    16141 attctccttc ttttataact acatcatcaa gtgctcttat ttctttatta aactcatcaa
    16201 cttttatttc tccacatcca gcaacacaac atttacccat acctctagca acaactgctg
    16261 catgtgacgt cattccacct ctagctgtaa ggattccttc tgctttaacc attccttcta
    16321 tatcttctgg agatgtctct agtctaacta aaactacttt ttctcctttt tcatttgctt
    16381 ttactacatc atcagcattg aaataaactt taccacttgc tgcacctggt gatgctggta
    16441 aaccttttgc tataaccttg gcttctttta atgccttatc ttcaaatttt ggatgtaata
    16501 attggtctaa ttgattaggc tcaattctca tgatagcctc tttttcatca attattccag
    16561 cttcaactaa atcaaccgct acatttattg ctgctgctgc tgttctctta ccatttctag
    16621 tttgtagtat atataatctt tcattttcta tagtaaactc tatatcttgc atatctttat
    16681 aatgaccttc aagtatatga gtaattttta caaattcatc gaatacagct ggcattacat
    16741 ctgcaagagt tgatatattt tgaggagttc ttatacctgc aacaacgtct tcaccttgtg
    16801 cattcattaa aaattcacca aataatttat tttctcctgt agctggattt ctagtaaatg
    16861 caacacctgt accactagtt tctcccatat taccaaatac cattgattga atatttactg
    16921 ctgttcctaa gttatgagct atatcattca atttacggta tacgattgca cgaggattat
    16981 tccatgatct aaatacagcc tctattgcaa gcattaattg ctcttttggg tcttgtggga
    17041 aatcattttt tatttctttt ttataaattg ctttaaattc ttttactatt tcttttaaat
    17101 catcagttgt aagttctgta tcaactgtgt atccctttgc ttcttttact ctgtctaata
    17161 cattttcaaa tttatatttt ggaacttcca tagcaacatc agaaaacatt tgtatgaatc
    17221 ttctgtaact atcatatgca aatctttcat tttgtgtagc ctctgctaag ccaacaacac
    17281 tattgtcatt aagacctagg ttaagaattg tatccatcat tcctggcata gagaatactg
    17341 caccagaacg aactgatact aataatggat tcttattgca tcctaatgtt ttatttaagt
    17401 ctttttctaa agtagctaaa tgctcttcta tttcttttat tatctctgct cttatacttt
    17461 cattgttaac ataataatca ttacatgctt ctgttgttat agtgaatcca ggagggacag
    17521 gtaagcctat cttagtcatt tctgctaaat tggcaccttt acctcctagt aaagatttca
    17581 tgtctttgct tccttcacca aaactataaa catacttagt ttccattgtt aaatccccca
    17641 ttaatctttt tattttaatt tatatcattt ttattaatag acattattaa atttctattt
    17701 ctttgtatat ctttagacca ttttctttca ttatgtctaa aattatacct gctgtttctt
    17761 ctattgcctt atttgaaacg tttattactg ggcatccaat tcttttcatt atctcttctg
    17821 aataatctaa ctcctgaagt attctttcta aattagcgta gtttgcttta ctggacaatc
    17881 ctaaagcttt taatctttgg gttcttatct cattcagctt ttcaggtgaa ttagtaagac
    17941 ctattatttt tttagtatct atctcaaaca cttctttagg aattggtatt tctggaacta
    18001 atggaacatt agctactttt atatttttat tagctaaata catactcaaa ggagttttag
    18061 atgttcttga tattcccact aaaattatgt ctgcttgaag aacacctcta gggtcttttc
    18121 catcatcata tttcactgca aattctatag cttcaactct cttaaagtaa gattcatcta
    18181 attttctaat tataccagct tctcttttag gttttcttcc tgttctcttg cttatttctc
    18241 ttagtatatc tgtcattaaa tctatacaac taagaccttc tctttcgcaa tatctttcaa
    18301 caatactgca taattcttca tcaactaatg tatatacaat taaagcgttt tcagcttttg
    18361 cattctccaa agtttcaagt agtactcctt tattaatcat gtatggaaat ctttttattt
    18421 cataagtttc attcacataa aactgagaca tacatgcctt tgcaacttgt tgtgcagtct
    18481 cccctactga atctgatact gcatatataa ttaggttttt caccagcata cctccttaat
    18541 tgtcaactat ttctaagaat agcttagtta tgttggtttt tgatattctc ccaacaactc
    18601 tcatatgatt tttgtcttct cccttatatt caacaatcgg aatcgaatct acttcatgtt
    18661 ctattatttt tcttgaagct aataaaacac ttgctccttt agttaaagtg actacatttg
    18721 gagttcttgt cattatcata cctattggca ttttatttat atcagaacct cctatagttg
    18781 cttttagcaa gtcttttctg gaaacaactc cacataactc ttcattctca tctataataa
    18841 ctatactccc tacatcagat aaaaacatag tgactattac atcatatata ctttcatcct
    18901 tcttagctag tacaggcatg ctcattatat cctctactgt tttttctttt acacttttac
    18961 caattaaatt tatttcacta actcctgaat aaaaatatcc aacttttggt cttgcgtcta
    19021 atattcctgt cattgttaat atagctaaat cagatctaag tgtagcacga gtcacattca
    19081 agctggaggc aatactttca ctcgttattg gttcattttc cttaactata tctataattt
    19141 ttagttgtct ttcattaagc tgaataataa tcaccttctt tcattgtgct atacttttta
    19201 tcttttcgca tcttatatag tatattatat aactatatat accattctgt aaacagattt
    19261 tttattgaat acgatatatt ttttactaag ttctctcgct taaagatatt tattatatat
    19321 taatggggga tatttcttta attaatagaa ctatattagt attacagtta atattataat
    19381 acataattgg tcattttaat tcattttata ttaaaatttt taataatatt atttcaatgt
    19441 gaatataaaa ttgcagaact aattcaaaat aatttttacg actacaaata acctataata
    19501 tacttttaaa gaaagtatcc taacaagaat atataaaaat ttaaaagggt tgatttaaaa
    19561 ataaccatca acccttttta ctaatatcta tttatattac catcaaatct tacccaaata
    19621 ttttttcttg caattgtctt aaatgatata aagtagtatc tttttctatc tctaccatat
    19681 cgtaagttat aacttcacct tttttaatat cttttacaac tttagtcttt ttacttatca
    19741 aaccaatagg tacagcattc atagcctttg ctacatcgta tttttctata gtaccatagc
    19801 atgtatatgc tccatagcca tccataaact cacctttttt caaatctttc ttagctatag
    19861 tcataacttc tgctactagt ccagctttag gtactattgt agccttatgg tctaagactg
    19921 ccatagctgc tgataaagga gtctctaaac tacataaatg atatggtcta tataatatgt
    19981 aattaggtcc atcacccata cttaaatatt ttagttcatc attaactgct tttaatttat
    20041 gggctactac tacgaaaact ccaggtgcta taccatttac aaaatcaact acaccataat
    20101 tatctaatac tccaccttcg ctttttaatg catatttctt aggtacttca ttaactgtag
    20161 cttcaatacc atgaccacct cttacatcag gcacaaatcc agttgcatta cacattaaag
    20221 ccatttctac cattgtttta gttccttctt taaaagaagc tatcatatga ggtgaagctc
    20281 cttttctttc tgcttcttct ctaactgtat caggattaca atctaaatct aatttattat
    20341 ttttaccttt acctatcact ctaacttcaa accccattgc atctgcaaaa tcaaataatt
    20401 ccattactgc acctggctca tctcctgcag aacctgtaaa tattactcca gcatcatctg
    20461 ctaatttttt aagtattggt ccaacaacac aatcagtttc agcatttaac ataactatat
    20521 gttttttatt taaaatagag tttaatgcta tctctgcacc aattgcaata cctccagttg
    20581 catctataac tacatctatt gacttagttt tacaagccac aagaaaatca ttacatgtca
    20641 atacttttcc ttcttgtaat tttatttctg catccttttc atttgttaca ttatctataa
    20701 tttcttcatc tattcctgca tcagtaaaag ctttatgagc caactccaaa tttatatcta
    20761 caacaataga agcttcaata cctttcatat ttgccatttg gcttaccatt ccatttccca
    20821 tatgcccagc tcctataaga gctactttta tttttttacc ttcctcttcc aattttgcaa
    20881 gttttctgtt taaatctaac ataccaattc ctcctgttat aataatttta ttttcaaatt
    20941 aagaaatagt tattaaatct ccaatagtta tatctggatt tcctatttcc acatgtattt
    21001 ctcctggtaa atttacttca cattttccat caaatttgat tgtacaatgc ccaatttctc
    21061 taagagtctt ctgagcaata tcaccaactg aaactataca ataatctcta ttccctatag
    21121 taagtgtatc tcctatttca acatcacttt ttaacgttgc tattgaatga attacagata
    21181 tatcctttaa gtcgtcatca ttaatggttt catcatatat aataagacaa ttgctttcat
    21241 ccattaactc tttaactaaa ctgcctatcc cacttatctt aacttcatat ttcatgacat
    21301 tcctcctgat aatttatatt tatattgagt taattaaaag aaacatttat tttttctttt
    21361 ataaatttta tagcttgtac aatactctct tcatctttaa atttttgctc tgcactatat
    21421 atatctaatc cttctatttc ttcaatctct ttaaatttag ccattactgt acgtcctttt
    21481 aaaatttctc caaactttat aaacccatct gaatctgaag atataatggc tatacttcct
    21541 ttagaaaaat agcttttctt tttgcctgta gacactatat cacccttttt tttagctcta
    21601 tttaaagttt taaaatacaa tttattctgc ttcattataa atatagtatt taaaatataa
    21661 gcaacaaata aaatcactaa taatttcata tttatacacc ttccaaaaat cacattattt
    21721 ttaaatctgt ataacaacta taaatgctgt acaatagtta tataaggttt ttaagtaaca
    21781 cctttttaaa ttctaaaaaa gttctacatt tacttatctt attcgttaat tttacatctt
    21841 ggcctatctt taaaacttct tcataaattt ttactaataa gtctgagtct atcttattct
    21901 cacatggaaa cattgtcata agaattattt ttatacttct atttgcatat tctattggtt
    21961 cttctaaaat tccaactgcc attaaaaact tatctgattt ttcatttaca gaatgaggaa
    22021 ataataaacc tttatcaaat actgtgggag atttttcttc tctattgact atattttttc
    22081 taaacttatc atcaatgcat cctaaatcca taagatggtc catcattttt tctaatgaag
    22141 caagtatagt cttttcattt aatatcataa atttatcttc atctaacaaa ttatttatta
    22201 gtaaatttgt agaattagta gtgtcaatat tcccttctct taggcacaat actgttttta
    22261 attgttctct tagtttgttt tcatcaaata ttgtatttat ttttaatact attgtattta
    22321 tatttgatgt gtctaaatca atagttgtaa aaactatatc atattcatct aagttaatat
    22381 ttctcaaatt aaaacttgaa agagtatcaa ttttaggatt atttcctatc agtttttcta
    22441 ctcttatttt caatagtttt gctgttccta gacctgtact acatataatt gctatttttt
    22501 ttattgaata gaatctactg ctatttcttt ctaaatatcc actgaaatgg attgctatat
    22561 atccaatctc atcttctgaa acttctaagt tatacttttt ctctattact tttcctgcta
    22621 tttgtgctaa tttaaatgga agtatataat tttgcttaat ctcttctaac aaaacatttt
    22681 ttaactttat attaaataat agcctgttta aagtaaaact aagatgatat cctagaccta
    22741 ctcttaattc atcctcattt ataaaaatac ccatatcgac atatatttga ttaaatatat
    22801 tttccatcaa ctcatcaatg tttttactaa ttctactact atttaaagca cattctgatg
    22861 ctggtgcatt tccactaact aacggtatag ttaaataaat aatttcttca tcatttaaag
    22921 tacattcaaa cattcctgat attatatgtt ttatttccct agcaataaag tattcatcat
    22981 atgatttaag taaatcaaac tttacatcat aatcttttac tttcttttct tcttttactc
    23041 tatagactaa aactactatg tagttaataa cttctcttaa catttcatct gtaacataaa
    23101 aattattttt tttaaataaa gtcaatagtt tttcttctaa atttatgatt tcttcttttt
    23161 tgattccttt aaaatacttt gaattactga aatctttcct tgagttttta tacaactgat
    23221 ttaatataaa cagtctaata tcaagttcat ttccatttaa tttcatacct gtattctgtt
    23281 ttttaatcaa gtttaaatta tatgaagcca aaactttttc tacatactgg aaatcattta
    23341 ctaaagtagt tcttcctaca cacatctcat cagctaaact atcaagtgta ataaatccat
    23401 ctagttctat caagtaattt agtataaact ctactctatc ttcttttgaa tttaatgaaa
    23461 atacattttt tctattcata tcaataatct tattgagtat ctgctcatct tttatttcta
    23521 gtttatagcc ttgacccttt atatatttga ttactgctat atcattacct aaatctttat
    23581 tcaattgttt tatatacgtc cttacacttc tagttgtgac attcaattca tttgctattg
    23641 agttaatact cacaaactct tttttactac acataatcaa tatcttaaat atcttgcggt
    23701 caatagaagg aattttctca gttacactca ttttgtatct cctccttgat ttcattctag
    23761 tacaaatttg aaaccaaatt aatacataaa atttcacttt aataaaggaa aatttagtat
    23821 taatctaact cgataattac agctaattaa tagtataaaa gctagtcttt cattaacaaa
    23881 aaatcttgac tagcttaaat ttatatttac aattttatta attaattcca agccttatat
    23941 tgacattaaa tattatctca atgcaaatac tgcaactcca tatgcaataa taacagctat
    24001 tggaccagtt attaaacgag agtaaaataa agctggaaca ccatactcta cagtttctgg
    24061 ttctgcttct cccaaactta atcctactgg tacaaaatca catccagctt gcccatttat
    24121 tgcaaataaa gctggaagtg ctaaatatgc tggtattgca ccaagaccaa tttgtgtacc
    24181 tacaagagtc cctactactt gagctataac tgcaccaggt cctagtattg gtgataagaa
    24241 tggaagtgtg caaattactg atataatcaa taatccacca atattacctg caagtggaga
    24301 tataactctt gcaatccagt ctcccagtcc agatgctaaa ataattccca taagcatact
    24361 tacaaatgcc ataaatggta ttacgttatt cattaccatt tggatagtat ctcgacctgc
    24421 atcataaaat tttgatacta cttgccctgc cccttgacca atagaaagta ttatgttctt
    24481 tttagcatat tcaccttgtg cttttgactt aacctcatca taattatcag gctttctaat
    24541 agaactctta ttttcgcttt tattttcttg agatttttgt ggcatatctt ccccatctac
    24601 aacacttata cagttaggat taacatctga tacataatat tcttctgtta taaattttgc
    24661 taaaggacct gtttttccaa ctggatttac atttattgta ggtatttttt tctttggata
    24721 aactccacat ctagcagttc caccacaatc aataataact actgctactt cttcatcaga
    24781 aactccagtt ttaaatccat ctacaatttc acaacccagt agttctttta tttttaatgt
    24841 tacttcatgg ataccaccag cagtcattga cagtatctta tttctattcc cttctttttt
    24901 tatatacaaa ggacctcccc agcctgaagt tcccttttct atttttaata ttttattctc
    24961 ctccatttta tctacctcct aagccttatt tgttgctcta ttttttcttg ttagaaaagc
    25021 atacattttt tctgttacta tacctcttat aaaaattaca attagaccaa ctataaaata
    25081 ccacaatgcc aatgtagtag tttctttacc taaagtagtc aaacctgcag atattcccaa
    25141 ccatacaaaa agttctcctg catttgcatg tggaaaaaga cctgtaattg gatgtacaaa
    25201 tgaaactgct gcatcataaa atcctgcttt gtgctcttct tttaaaaatc taccaaatgt
    25261 atagcacata ggatttccca agaaaaatac tgatactaat ggaagtagaa tatatcttgt
    25321 aaaagagttc tttcctagct tagaagccca attattaact ctttcctcac caattatctt
    25381 aatcaaagag ttaatagcta ccattaatac aattagcgtt ggaagagtac ctgaaacaag
    25441 acctataaat tgttctcccc ctttctgaaa caaaccgata aaccactctg cacctttact
    25501 tagacctgta ataacgtttt ccataaaatt ataacctccc tataatatct ttaaattttt
    25561 aattttactg cttaccataa attttacaaa ttacatcttt tttctgtac
//
LOCUS       DAMJVG010000057        24944 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.057, whole genome shotgun sequence.
ACCESSION   DAMJVG010000057 DAMJVG010000000
VERSION     DAMJVG010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24944)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24944)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24944
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.057"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(57..665)
                     /locus_tag="PC512_002512"
     CDS             complement(57..665)
                     /locus_tag="PC512_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HDF2442247.1"
                     /translation="MEKDFFRKNGIDLAKSILGKYLIRKYENKVIVTKIIETEAYMGV
                     NDKGAHVYGNKKTDRTKPLYLDGGHIYVYLIYGMYNCLNLSANIENVPECVLIRGVEP
                     ITSLDEISMNRYNKAYTELSKYQVKNITNGPGKLCKALKIDRSLNSKSIMGEELYISD
                     FYYDDKGKKVFSKDELDIKTSKRINIDYAEEAKDFLWRFYIE"
     gene            complement(774..3512)
                     /locus_tag="PC512_002513"
     CDS             complement(774..3512)
                     /locus_tag="PC512_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing sensor histidine kinase"
                     /protein_id="HDF2442248.1"
                     /translation="MESKGTLSKNKVYILANGLFLVIALLNINLYTVSINMYRIILLW
                     IFGYSIVYISSFKTDEFINILKVGCLVLVFVSILGVVNLKIQKFQIVLLNLSIINMST
                     FIYLTISKVKKLRISPILIFYSAFVILDYFIRNIFSDINWNMIIILINVCISMFNLLY
                     LLNKLDSNIEHYKLIKDLTYFVFFTTIICFVAISKINIVDSDRLIGVIYLLLCNHTYY
                     VYVYSLNNRVVYPYYELDSINKKLSKKSEQLGKINLAIEKDMIIQRTLKNYIDQRKEL
                     LRQALDTIPNVWIVTDYDFNISYTNNKFKDEFSKDMNNYYKILTFIKEDEKVAEKLKK
                     FDNDISIIDKLVELNDKIYLLSLSNNKDESNYLISLNDITNEIKIDEEIRNINKDYEN
                     IILNIPSPILVRSAEGGIKKNKVISINKKYEKSFKCVSSDLVDMTLEQYFETFNIDFF
                     DNREFKRLNLTQEKKAEIVSYNDTANCIVNFVMSDSEGEEHVEEVRVGDYWSDNKLFK
                     LLTFRDITKEINILRTVNEQKIIYEKLLDVIPEAIFLEDLSTSRVLYTNRAFRELFGI
                     SSDVLGVTTQKYRNILVKKYINNLNIGEREKSIHIVNENNHIKEVKMISRTLYFGQKR
                     SRVRIIKDLSVQRESERLKKALIKQRQYDQMKMEFYANISHELKTPLNNIYSSVQLIE
                     NLYKKGKIIDFQDILKEHIKITKQNMFRLLRLIDNIINISQVKSDIYKIKAVNFDIID
                     ITERIVTSISSYAKSKGIDLIFDTDEETVMVGLDPESIERIILNILSNAIKFTLEGGE
                     ILVGIYKKDETVEIIIKDTGVGIDKEKLNDIFNRFKQIENSGISNEFGSGIGLCLTKS
                     LIEIQNGKIYIDSKVGEGTNVKVIFPIKEVVEEVYDNSNYNDNIEKFEIEFFDIYK"
     gene            complement(3660..4451)
                     /locus_tag="PC512_002514"
     CDS             complement(3660..4451)
                     /locus_tag="PC512_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011987989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF2442249.1"
                     /translation="MKLKKLLSVALVSAIAISAVGCSNKEDKKILVGASSNPHAKILE
                     VAKPLLKEKGYDLEVKIFDDYVLPNTALDEGSLDANFFQHIPFLEETVKEKGYKLTYT
                     SKVHIEPMGFYSEKVKSLDELKDGAVIAVPNDATNGARALKLLAKNKLIEVKDGELIT
                     KKDITKNPKNIVIKEMNAEQLPTVLKDVDGAVINSNYALTANLNPTKDAIVIESSDSP
                     YVNIIACRENNKDSDKIKALSEAMNSKEVKKFIQDEYKGSIVPAF"
     gene            complement(4487..5143)
                     /locus_tag="PC512_002515"
     CDS             complement(4487..5143)
                     /locus_tag="PC512_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2442250.1"
                     /translation="MNSLIDFLTTLFPNALLQTLYMVIVPTIVATILGFILAIILVVT
                     KPDGLKPNSTINSALGFIVNIFRSFPFMILIVAMIPITRLIVGTSIGETAAIVPITIG
                     AAPFIARIIESSLNEVDKGLIEAAKSFGATKRQIVFKVMIKEAMPSIVSGITLSIISI
                     LGYTAMAGAVGAGGLGNIALIYGYQRFDTAVMVYTVIALIILVQIIQGVGNLAYKKLK
                     "
     gene            complement(5136..6101)
                     /locus_tag="PC512_002516"
     CDS             complement(5136..6101)
                     /locus_tag="PC512_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HDF2442251.1"
                     /translation="MISIKNVNKYYGKIQVLKDVSIEIESGEIFGIIGHSGAGKSTLL
                     RCINGLEEYQEGSVLVSDKEVKSLNEKQMRDLRKELGMIFQHFSLLERKTVFDNVALP
                     LECFGYSKAEIKKRVLELLEVVGISEKKNDKPRNLSGGQKQRVAIARALALNPQVLLC
                     DEATSALDPNTTKSILSLLEDINKNLGITIIVVTHQMEVIKQICGRVAIMENGEVLEV
                     GDTEEIFLRNTKGLRKLIGEESIILPKGTNIKILFPKDISNEAIITTMARELNIDVSI
                     IFGKLEQFKDDILGSLIINISDKSGEQVKQYLTSKGIRWEEMINE"
     regulatory      complement(6207..6313)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(6603..7547)
                     /locus_tag="PC512_002517"
     CDS             complement(6603..7547)
                     /locus_tag="PC512_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YafY family transcriptional regulator"
                     /protein_id="HDF2442252.1"
                     /translation="MSRAERLIELMITINAKRSFTAGELAEEFSVSKRTILRDLQVLE
                     SIGFPLYSKVGAAGGYHVLKERILPPIAFSESEVKSIFFAYQSLEYYNDLPFEQETIS
                     VLKKFLNCIPNDIQYNIENIRRKFVFWTPDRHCSTPLLKELFNIVMNESTIKIEYSSK
                     QKNSVRTIVPIGLYAMNGLWYCPAYCIKSASIKEFRVDRIVKILSIENLSSKKYKVLS
                     SIHDYLKNMEVGTDYHIKINLTDEGVKRCETEFLLARGLKILSKGGYIDMYIPKSTLN
                     WVAEYFLTFGKNATIIEPIELKHLVKSKVLELYNHHCI"
     gene            7658..8125
                     /locus_tag="PC512_002518"
     CDS             7658..8125
                     /locus_tag="PC512_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442253.1"
                     /translation="MENNTIKADDIINYCLSNLDDVLLMNSWGERAIYYNPNGILKRG
                     VYVLTIKEKDSNHDKGSLVSRPNVYRVNIGLKKETFIEMFGYIPKRPGVGQIVDMDFD
                     FTKLDTIMPHPIYSWMGWICVLSPTEKTFENFKTLIGESYNFAKQKFKKRKNK"
     gene            complement(8295..8894)
                     /locus_tag="PC512_002519"
     CDS             complement(8295..8894)
                     /locus_tag="PC512_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442254.1"
                     /translation="MKLKRTLFVGLALVLAIGITACTKNNEKPSENTGKNPNESVNNN
                     EGYMNYYSTSYNDYIAGLNRYSIYDTPESINNQFKDKEYPGNEKYLSDVKAAYKDSRD
                     KIQSFVTSLKKDGKTEDTELKKMNDDLIAEGERLVKDIDKRIEKLDKVSDEDMKKGQN
                     DFIKLVHGTEDVGNDIGSGFRKMIKDMNDRLGITGNNKK"
     gene            9140..9736
                     /locus_tag="PC512_002520"
     CDS             9140..9736
                     /locus_tag="PC512_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3793 family protein"
                     /protein_id="HDF2442255.1"
                     /translation="MSCCNSQFCCKNKIESSYIKWLLEVLGPVFLGSKPAEIINISFT
                     DVNREEKINDIYKYLYKCKKIDFIVIDKEKKGLKILFVNKKALSEKLKCKKTVNFLKF
                     LGYKQNTNVNAYLEHLVDKLKSDVFPDEIGIFLGYPLKDVIGFMGYSNYEVSMIKYWK
                     VYGDTKQSEDTYSKFLLHRKKMRKLLDYISVDKIVSCF"
     gene            complement(9834..10793)
                     /locus_tag="PC512_002521"
     CDS             complement(9834..10793)
                     /locus_tag="PC512_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NrtA/SsuA/CpmA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF2442256.1"
                     /translation="MTSLIMVLVGTVGCSTTNDKKDEPAKKEASLPKEINLTYVKSPL
                     NVPSILEKKDDLFGKEFKKDNIKVNFHELTTGPEQTQALAAGELDFLHALGGTSAIIA
                     ASNGVGLKITNIYSRSPKGYMLITNNDNIKSIKDLKGKKIVGPKGTILHQLLIAALAK
                     EGYTIDDVEYVNMDIPSAASALESKSADVAMLAGPVALKTINSGAKMIVNGEGLVSGI
                     IVTAVSDDFAEKYPELVKRFMKVHEETLKYMNENKDEVMDVVSKEVGLSLDETKEMYS
                     WYDFSSKITDKDIKELEDTQEFLMSNGMQQKKINIKDMLYNQN"
     gene            complement(10827..11558)
                     /locus_tag="PC512_002522"
     CDS             complement(10827..11558)
                     /locus_tag="PC512_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2442257.1"
                     /translation="MVRSGFLLENIYKKYLVDNKEHLVLDNISLNISSEEITVILGES
                     GCGKTTLLRILAGLENATSGNIYFFNNDKKCTPKVGMVFQESRLMPWLNVSENILLHT
                     EKDNRNKVDLDKYLKMMKLEKFKNSYPNELSGGMAHRVSIARALSFNPDILLMDEPFA
                     ALDYFTRRKMQKEVVNIHKNTKKGVVFVTHNIEEAMEIAKKIIVFSKNKRIKQFSVED
                     EYNRDLTKNYYINLKKEILRELGEF"
     gene            complement(11551..12321)
                     /locus_tag="PC512_002523"
     CDS             complement(11551..12321)
                     /locus_tag="PC512_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2442258.1"
                     /translation="MFEKIHKRLKGYYIFLIILILWKIVCVLGIWSSYILPPPEIVLD
                     TFIKMIYDGSIFLNVYASVRRILIGFLISSLMAIPLGVLFGVNKKMYEYFKPLFEFMR
                     STPPLALVPMLILWFGIGEESKIIIIILASFFPIFLNTLKGIKNCDNKLIEVGKSFNL
                     SKKRIFYKIIIPNSMLDIVVGLSLGLGYSFRAIIGAELIAASSGLGYLISDGKDMSRT
                     DVVLVGIFVIGFLGILSDYLFSKIITKFSKGKQVDLNG"
     gene            complement(12406..13116)
                     /locus_tag="PC512_002524"
     CDS             complement(12406..13116)
                     /locus_tag="PC512_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIM24 family protein"
                     /protein_id="HDF2442259.1"
                     /translation="MFKFDVTNELMCIARGSGKFFAKKGAMVAFKGNFNFEKLLLGPS
                     NGGGLGRALLGHVQRSLTGEQMPIMVVEGEGEIYLAQNAYHVDVISIDPGDSIYVESE
                     NLLAFSEQLNYSVKLIGSGVISQKGLFTTHLVNKTGQNQDVAIITDGNPLILEGPCCV
                     DPDALVAWTGREPYPKVSKLSWKTFIGQTSGESYHMEFVEPGQIVIIQPSERLSGLKT
                     DSTPSDRMSSGGLRLGID"
     gene            complement(13296..13448)
                     /locus_tag="PC512_002525"
     CDS             complement(13296..13448)
                     /locus_tag="PC512_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HDF2442260.1"
                     /translation="MATFIIAAIVVVLMALAVMYMVKNSKKNGSSCGCGCSGCSSSKS
                     CHSAKR"
     gene            complement(13474..15630)
                     /gene="feoB"
                     /locus_tag="PC512_002526"
     CDS             complement(13474..15630)
                     /gene="feoB"
                     /locus_tag="PC512_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HDF2442261.1"
                     /translation="MSIKIGLIGNPNCGKTTMFNGLTGSSQYVGNWPGVTVEKKGGKL
                     KGNKDVEIVDLPGIYSLSPYTLEEVVTRNFMLDDKPDAVINIVDASNIERNLYLTTQV
                     LELGIPTVIALNMMDIVNKNGDKINIKELSEVIGCPVVEVTAVKGQGIMEAAEKAVEL
                     ASSNNKLNFKLPFVDESKDAIEKIEKIIEEKTPYIDVETRWLAIKLFERDENVIQKLD
                     ISKTILNSIEEITRNCEDELDDDSESIITANRYEFISSIISSIIKKNRKGKETVSDKI
                     DKIVTNRILALPIFALIMWGVYYIAVSSLGTIATDWTNDVLFGEIIQGNVSNFLASLN
                     VAEWLQGLVVDGLIGGVGAVLGFVPQIMLLFLLLSILEDCGYMSRVAFIMDRIFRKFG
                     LSGKSFIPMLISSGCGVPGVMSTRTIENDRDRKMTIMLTTFIPCGAKIPIIALFAGAL
                     FGGASWVAPSMYFLGIAMIIICGIILKKTSLFAGEPSPFVMELPQYHIPSAKGVLIHM
                     WDRGKAFIIKAGTIIFVACGVIWFLQSFNWSLQMVDAGDSILASLGNIVAPIFAPLGF
                     GNWQSSVATVTGLVAKENVVGTFGVLFGISDATEQDPTLLASVASMFTVASAFAFMAF
                     NMLCAPCFAAIGAIKREMGSWKWTWITLGFQTLTAYIIALLINQVGSLVLGTGGSIAG
                     AIISIFIAVAVVFVVLTYSNKNMKKEKMGKLSYMKN"
     gene            complement(15730..15951)
                     /locus_tag="PC512_002527"
     CDS             complement(15730..15951)
                     /locus_tag="PC512_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HDF2442262.1"
                     /translation="MNRLKDIKCGETVKVKKLEGEGATRRRIMDMGITRGVNIFIRKV
                     APLGDPIEVTVRDYELSIRKSDAEKIIVE"
     gene            complement(15964..16176)
                     /locus_tag="PC512_002528"
     CDS             complement(15964..16176)
                     /locus_tag="PC512_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HDF2442263.1"
                     /translation="MMPLILSNTGEEVVIKKISGSDKTRTFLNSIGFVVGTNVKIVSK
                     IDGNLIIDVKDTRVALDKKMASRIII"
     gene            complement(16497..19394)
                     /locus_tag="PC512_002529"
     CDS             complement(16497..19394)
                     /locus_tag="PC512_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF2442264.1"
                     /translation="MKAFKKHFLILSLIFLLIISCFNNILCFADESENSKKIRVGYCD
                     DYGIISSSKEHSYTGYGYDYLREISKYTRWEYEFVKGSWEECLDRLEKGEIDLLGPLQ
                     KNDERNKLFNFPKLNSGYEYSVLYTKDSNNNMFYEDISSFKGMRVAVLRGNFHNIAFE
                     KYREENNFSVEYIYCNSIDELIESVNEKKADAFVCGSIINAKGMKIVSKFSVEPFYFA
                     TAKYKPNLVKELDYALKELKINDMYYELELYKKYFKREVNNSIAFTRQEMNFIKANPK
                     LTMVYDSEWSPVEYYDKESNSFKGISSNLMSIISKKCGIKFEYIKTKNYNESLDYIKS
                     GKANMLCGSINENDKAKRFNMKLTNPYINIPMIMVGKLDTNLNNDLNIALTSSYKSID
                     SYIEKSFENAKTTSYKSIESCLNAINEGKANLMILSSYQFDELLREGKSENLSVISVL
                     DTSYGMRIGVSNKTDPILVSILNKSIDKITEEELSDCIYSNTIDKPYKVPFGVIFKEY
                     SIQIISFVCILFLIAIKYIIYNKKKKEDYLKKIAYTDPLTGADSIDKFKINSNKLFAK
                     NNPEEYALFYIDVDKFKYINDMFGYDMGNDTLIHISNTIASELKEDEIFARVSADHFV
                     LLIKYKTDDDIKTRLNNIYNKVQILSNPKINYYKLILDCGIYKISKSDNDINTIMDRA
                     NTARKTIKGGHKNSFAFYDKEMHKKILKEKEIENSMVDALNNGEFIVYFQPKYSLSDY
                     QIIGAEALVRWDNPQKGLIPPIEFIPVFERNGFIVNIDFYVFEEVCKKIREWMDEGQK
                     VVPISVNLSRMHFVNSNFIEKFKLIVDKYKIPTRLIELELTETAVLDNIEGLLDTMNN
                     LKEKGFVISMDDFGTGYSSLNLLKELPVDILKLDRAFFTEKDESNNEKIVISNVIKMA
                     KELKMKVISEGVETISQVEFLKQIGCDMVQGYLFSKPMPVKEFEKIAFKKE"
     gene            complement(19721..20329)
                     /locus_tag="PC512_002530"
     CDS             complement(19721..20329)
                     /locus_tag="PC512_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dienelactone hydrolase family protein"
                     /protein_id="HDF2442265.1"
                     /translation="MVDNLIKYIHKSYVAIVVLHEIYGINSFIEDVCQKYYKYGYDVF
                     CPELLGEKRVFPYSKVQEAYDFFINNVGFDIYKKVEKLINDLKSEYKYVFVAGYSVGA
                     TIAWRCSEDSFCDGIICCYGSRIRDYMDVIPKCPTLLVFAKHDSFDVDSISYQLSRKQ
                     NIQIEILDANHGFIDRYSNNYSDIQTKVFTIKEKSFLSKYLA"
     gene            complement(20589..21134)
                     /locus_tag="PC512_002531"
     CDS             complement(20589..21134)
                     /locus_tag="PC512_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH peroxidase"
                     /protein_id="HDF2442266.1"
                     /translation="MKKFVCTVCGYIHEGDAAPAQCPVCKVGADKFEEMKGEKNWADE
                     HRIGVAQGVDEEIIEGLRANFVGECTEVGMYLAMSRQADREGYPEVGEAYKRIALEEA
                     EHAAKFAELLGEVVVADTKENLRVRVDAEYGATDGKLKLAKKAKELGLDAIHDTVHEM
                     CKDEARHGKAFLGLLNRYFGK"
     gene            complement(21252..23075)
                     /locus_tag="PC512_002532"
     CDS             complement(21252..23075)
                     /locus_tag="PC512_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2442267.1"
                     /translation="MNLSTGNQKVSRLKKKEKPKDFKKTFKRIFMYFKKDKKITRFIF
                     LLVIIDSIISTVIPYTIGKVVDIIDIDTYSKSIFLKGIIILLSFYIIEFSVKLSKGIC
                     TARLSQSIVREMRSNLFLKFKNLPITFFDKSSTGDIMSRVTNDVDNISTGISNSLVQL
                     ITGILNILMTFIMMFVLSPILTFCSVILIPIVMFVSNFIAKRTRVFFKQQQVELGKLN
                     AHIEEMISNINVVKSFNYERKSVNDFKEVNDRLLNISLKSQIYTSLLMPIMNVISNIG
                     FATICIIGGILASKDIITIGVIASFLSYVRQFTRPLNELANLFNTLLSAIAGCERVFE
                     IIDEQEEQEVHNMFKSEINDNKDGNLNSHFVKGEIELKDVSFSYDSKKKILDNINLKI
                     KSGTSNAIIGETGSGKTTIINLITNFYHIDEGSIFLDGKDIYSINRNYLRTCFGVVPQ
                     EGYIFNDTVMENIRYGNLEATDEEVIYASKIANAHKFIVKMREGYSTVLSDRGEDLSE
                     GQKQLISIARAVLKNAPILILDEATSNIDIATEAKIQEAINNLTYGKTSIIIAHRLST
                     ISNCDNIIVLENGRIVESGNHKELIKLKGHYYRNILLTQGK"
     gene            complement(23088..24863)
                     /locus_tag="PC512_002533"
     CDS             complement(23088..24863)
                     /locus_tag="PC512_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2442268.1"
                     /translation="MRYFKKYIKKYIVLFLTAVFFLTLEAFCDLAQPTIMAKIIDIGV
                     SNKNLDYILSTGAIMIGITFLGAIFAIIRSVISARVSQHFSYDLRQDVFEKINTYSLK
                     QIDKFGRASLITRITNDINQMQQFVNGMMRVFIKSPIMCIGSLIIAIKLNLKMSIIIL
                     IAVLIIFIIILLNMKIGYRLFKNVQESTDKVNSKLRQFLSGIKVVKLFCRYDYENQSF
                     EELNDELFKNSRKATTMMSFFRPTITIIINVSIIIILLIGRHLIYSGEIKIGIIVAYV
                     NYMTRILTSLIMISHVFNVFVRAKASYERISEVLVDENEEVIEREESLDVGEKDLKFV
                     NCDIIFENVDFSYNKNTDEKILKNVSFKIEEGQNIGVIGQTGSGKTSLVNLIQKLYII
                     DKGDIKIGGRSIYSISEESLRARIGVVFQNSSVFGKSILENVVMGNRDICKEDVVKSC
                     EIANANQFITKLENTYDEVLFQRGKNLSGGQRQRITIARAIAKKPQILILDDCFSAMD
                     INTETIIRKNIKEYISNLREKESKKCTVITISQKISSIIDCDKILVLDEGEVVGFATH
                     EDLLVSSPIYKKIFALQNLVSEDVN"
BASE COUNT         8228 a         4322 c         2436 g         9958 t
ORIGIN      
        1 agatacatac ctataaaata ccttcctata gatacatatc ttacctatat aaaaacttat
       61 tctatataaa aacgccataa aaaatctttt gcttcttctg cataatctat atttatacgt
      121 ttactagttt ttatatctaa ctcatcttta ctaaatactt tttttccttt atcatcataa
      181 taaaaatcac ttatatataa ttcttcaccc attatactct tactatttag acttctatct
      241 atttttaaag ctttgcaaag ttttcctggt ccgttagtaa tattttttac ttgatattta
      301 ctcaactcag tgtaagcttt gttgtatcta ttcatagata tctcatctaa agaagttata
      361 ggctctaccc ctcttattaa tacacactct ggcacatttt ctatatttgc agataaattc
      421 aagcaattat acataccata aattaaataa acatatatat gtccaccatc taaatataat
      481 ggcttagttc tatctgtctt tttattgcca tatacatgtg ctcctttatc atttacaccc
      541 atgtatgctt ctgtctctat gattttggta acaattactt tattttcata tttccttatt
      601 agatatttac ctaatattga tttggctaaa tcaattccat tttttctaaa aaaatccttt
      661 tccaaaattt cacctcataa aatttattta aaacgcatca aatacaacta aagtaataaa
      721 taaaattaac tcttattaat gtgatatata taaacaataa atttagacat ttattattta
      781 tatatatcaa aaaattctat ctcaaacttt tcaatattat cattgtaatt tgaattatca
      841 tatacttctt caacaacctc tttaattggg aatataactt ttacattagt tccttctcct
      901 accttactat ctatgtaaat cttcccattt tgaatttcaa tcaatgattt tgtaaggcat
      961 aaacctatac cacttccaaa ttcatttgat ataccactgt tttcaatttg tttaaatcga
     1021 ttaaatatat catttaattt ttctttgtct atgcccactc cagtatcttt tataattatc
     1081 tctactgttt cgtctttttt atatatacct acaaggattt ctcctccttc taaagtaaat
     1141 tttatagcat ttgataatat atttagtatt attctttcta tcgattctgg gtcaagccct
     1201 accataacag tttcttcatc tgtatcaaaa attaaatcta ttcctttaga cttagcataa
     1261 ctactaatag atgtaactat tctttctgtt atgtcaataa tatcaaaatt aactgcttta
     1321 atcttatata tgtctgactt aacttgagaa atatttatta tattatctat taatctcaat
     1381 aatctaaaca tattttgttt agttattttt atatgttctt ttagtatatc ctgaaaatca
     1441 attatttttc cttttttata aaggttttca ataagttgaa ctgaactata tatattattt
     1501 aaaggtgtct taagttcatg agatatatta gcataaaact ccatcttcat ttggtcatac
     1561 tgtctttgtt ttattaatgc ttttttaagt ctttcagact ctctttgcac acttaaatct
     1621 ttaataattc tcactctact tcttttctgt ccaaagtata atgttcttga tatcattttt
     1681 acttctttaa tgtgattatt ttcatttact atatggatac tcttctctct ttctcctata
     1741 tttaaattgt ttatgtattt ttttactaat atatttctat atttttgtgt tgtaactcct
     1801 aatacatcac tagaaattcc gaacaactct ctaaaggctc tatttgtata tagtactctt
     1861 gatgtactta aatcctcaag aaaaatagcc tctggtataa catccagtaa tttttcatat
     1921 attatttttt gttcatttac tgttctaaga atatttatct ctttagttat atctctaaat
     1981 gtaagcaatt taaagagttt attatctgac caatagtctc caactctaac ttcttcaaca
     2041 tgctcttcac cttctgagtc agacatcaca aaattaacta tacagtttgc tgtgtcattg
     2101 taacttacta tttcagcttt cttttcttgt gttagattta atcttttaaa ttccctattg
     2161 tcaaagaaat ctatgttaaa agtttcaaaa tattgttcta atgtcatatc gactaaatca
     2221 cttgaaacac atttaaaact cttttcatat tttttattta tacttattac cttattcttc
     2281 tttatgccac cttcagcact tcttacaagt ataggagatg gaatatttag tataatgttt
     2341 tcatagtctt tatttatatt tcttatttct tcatctattt tgatttcatt tgtaatatca
     2401 tttaaactta ttaagtaatt gctttcatct ttattattac ttaaacttaa caaataaatt
     2461 ttatcattta actctaccag tttatcaatt atacttatat cgttatcaaa tttcttcaat
     2521 ttttcagcaa ctttttcatc ttcctttata aaagttaata ttttataata attattcata
     2581 tcctttgaaa attcatcttt aaatttatta tttgtgtaac ttatattaaa atcatagtct
     2641 gttactatcc atacatttgg tattgtatcc agagcttgtc taagtaattc ttttctctgg
     2701 tctatgtagt tttttaatgt tctttgtata atcatatcct tttctattgc taaatttatc
     2761 tttcctaatt gctctgactt tttacttaat tttttattga ttgaatcaag ttcataatat
     2821 ggatacacta ctctattatt aagactgtat acatatacat aataagtatg gttacataat
     2881 agtaaatata ttactcctat taatctatct gaatctacta tattaatctt agaaattgct
     2941 acaaaacata taatagttgt aaaaaaaaca aaatatgtta aatcttttat taacttatag
     3001 tgctcaatgt tactatcaag tttattcaac aaatatagta aattaaacat agatatacaa
     3061 acattaatta atataataat catattccag ttaatatcac taaaaatatt tcttataaag
     3121 taatctaata tcacaaaagc actataaaaa attagtattg ggcttattct tagttttttt
     3181 actttagaaa tggttaagta tataaaagta gacatattaa ttatgcttaa gttaagcaat
     3241 acaatttgga atttttgaat ttttaaattt actactccta aaatacttac aaaaactaat
     3301 acaagacacc ctactttcaa tatatttata aattcatctg ttttaaagct acttatataa
     3361 actatagaat atccaaatat ccaaagtaaa attattctat acatatttat agaaactgta
     3421 tacaaattta tatttaaaag tgcaataacc aaaaataacc cattagctag tatatagacc
     3481 ttattcttac ttaaagttcc tttagattcc atattcccca ccacttcttc atttttatat
     3541 agttttacct ataaatatgt taccacaatt cttccaaaaa atttgtcact ttctagttat
     3601 aaaaaaaaat gagtaaatat ttttaatttt actcattttg tagattttgt atattcagtt
     3661 taaaaagctg gaactatact tcctttatat tcatcttgta taaatttttt aacttcttta
     3721 ctattcatag cctctgataa agccttaatc ttatcactat ctttattatt ttctctacaa
     3781 gctattatat ttacatatgg agaatcactt gattctatta ctattgcatc cttagtagga
     3841 tttaagttag ctgttaaagc ataattagaa tttattactg ctccgtcaac atcttttaat
     3901 actgttggta attgctctgc attcatttct tttattacta tatttttagg atttttagtt
     3961 atatcttttt tagttataag ctctccatct tttacttcta tcaatttatt ttttgctaat
     4021 aatttaagtg ctctagctcc attagttgca tcatttggca cagctataac agctccatct
     4081 tttaattcat ctaatgactt aactttttct gaatagaatc ccattggctc tatatgaact
     4141 ttagatgtat aagtaagttt atatcctttc tccttcacag tttcctctaa aaatggaata
     4201 tgttgaaaga agttagcatc caaagaccct tcatctaaag ctgtatttgg aagtacataa
     4261 tcatcaaata tttttacttc taaatcatat cctttttctt ttaacaaagg ttttgcaact
     4321 tccaatatct ttgcatgtgg atttgatgaa gctcctacta gtattttttt atcctctttg
     4381 tttgaacaac ctactgctga tattgctatt gctgacacca atgctactga taataatttc
     4441 tttaatttca tttttactcc ccctctttaa aatgtttata attaatttat tttagtttct
     4501 tataagccag atttcctact ccctggatta tctgaactaa tattataagt gctattacag
     4561 tatataccat tactgctgta tcaaatcttt gatatccata aataagtgct atattaccta
     4621 atcctccagc tcctactgca cctgccatag ctgtataacc aagtatagat attattgata
     4681 atgtaattcc agatactatt gaaggcatag cttcctttat cataacttta aatactattt
     4741 gtctttttgt agctccaaaa gattttgctg cttctatcaa tcctttatca acttcattta
     4801 atgagctttc tataattcta gcgataaacg gtgctgcccc aatagttatt ggcactattg
     4861 cagcagtttc ccctatactt gttccaacga ttaatctagt tattggaatc attgcaacta
     4921 taagtatcat aaatgggaaa cttctaaata tatttactat aaatcctaat gcactattta
     4981 ttgtgctatt tggttttaat ccatctggtt ttgtaactac taatatgatt gctaatataa
     5041 atcctaatat tgttgccact atagttggta ctataaccat atacaaagtt tgtaacaatg
     5101 catttggaaa tagtgttgtt aaaaagtcaa ttaaactatt catttatcat ttcctcccat
     5161 cttatgccct tactagttag atattgtttt acttgctctc cacttttatc tgaaatgttt
     5221 ataataagtg aacctaaaat atcatcttta aattgttcta atttcccaaa tattatagac
     5281 acatctatat ttagttctct tgccatagtc gtaataatag cttcattaga aatatcttta
     5341 gggaatagta tctttatatt tgttcctttt ggcaatatta tactttcttc acctattaat
     5401 tttctaagtc ctttagtatt tcttaagaat atttcttctg tatctcctac ctctaatact
     5461 tctccatttt ccattattgc tactcttcca caaatctgct ttataacttc catttgatga
     5521 gttacaacta ttattgttat tcccaaattt ttatttatat cttcaagcaa tgaaagaatt
     5581 gactttgtag tatttgggtc taatgctgaa gttgcttcat cacaaagaag tacttgtgga
     5641 tttagtgcta aagctctagc aattgcaacc ctttgttttt gtccgccact tagatttctg
     5701 ggtttatcat ttttcttttc agatattcca actacttcta ataactctaa aactcttttt
     5761 ttaatttctg cctttgagta tccaaaacat tctaatggca atgctacatt atcaaataca
     5821 gtttttcttt caagcaatga aaagtgttga aaaatcattc ctaactcttt tcttaaatct
     5881 ctcatttgct tttcattcaa tgactttact tctttatcag aaacaagtac actgccttct
     5941 tggtattctt ctaatccgtt tatacatctc agtagtgttg atttccctgc accactatga
     6001 cctattattc caaaaatttc tccagattct atttcaatac ttacatcttt aagcacttga
     6061 atctttccat aatacttatt aacatttttt atgctaatca taaaatttcc tcccatatat
     6121 tctgctcagt ttttatgttt atcctctctt atgtattaca acaaaataaa agcccgagta
     6181 taaactcagg cttagaaagc tatttatact catctatcaa ctatattagt tgcaggattt
     6241 agcaccaatg tatataaaat atactggttg ccgggtttca aagggccagt ccctccacca
     6301 ctcttgataa gacgttattt aatttaattc tattatcatt tgttgctatg ttatatatga
     6361 tatattcatt aatagtattt gtcaataaat ttatttaaat tttttatttt ttattatcgt
     6421 taattaacta tttttaatta gttttctagc tcctaacact ttatatttta atgtctatat
     6481 aactatagaa catcattata agaaataaat taaataacat caatctatct aaatcatctg
     6541 taaagtaaat taagaaaatt aacattttat ccaaactcta tcctactatt aaataaaata
     6601 atttaaatac aatgatgatt atatagctct agtactttag actttaccaa atgtttaagt
     6661 tctataggtt ctattattgt agcatttttc ccaaaagtta aaaaatattc agccacccag
     6721 ttaagtgtag attttggtat atacatatct atgtatccac ctttagacaa gattttcaac
     6781 cctcttgcca acaaaaattc tgtttcacaa cgttttactc cctcatctgt caaattaatt
     6841 ttaatatgat aatctgtacc tacttccata ttcttaagat aatcatgtat agaagataaa
     6901 accttatatt tcttacttga taagttttct atactcaaaa tcttcacaat tctgtctaca
     6961 cgaaattcct taatagatgc tgattttata cagtaagctg gacaatacca aagtccattc
     7021 atggcataca aaccaatagg aacaatggta cgtacactat ttttttgctt tgatgaatat
     7081 tcaattttaa ttgtagattc attcattact atattaaaca attctttcaa taatggtgtt
     7141 gaacagtgcc tatctggtgt ccaaaaaaca aatttacgcc ttatattctc aatattatat
     7201 tgaatatcat ttggtataca atttaaaaat ttttttaaaa cagaaatagt ttcttgctca
     7261 aatggcaaat cattataata ttctagtgac tgatatgcaa agaatataga ttttacctca
     7321 ctttctgaaa atgcaatcgg tggaagtata cgctctttaa gtacatgata tccaccagcc
     7381 gctccaactt ttgaatataa tggaaatcca atactctcca gcacctgtaa gtctcttaat
     7441 atagtacgtt ttgatacaga aaattcttct gctaattctc ctgctgtaaa acttcttttt
     7501 gcatttattg ttatcatcag ttcaattaaa cgctcagctc ttgacatatt tatactccta
     7561 atttaaatat agtgacaata attgtcacta ttatatgata agatattctt acatttaaag
     7621 caataataat agtaaagaaa gaagggactg atactttatg gaaaataata ctattaaggc
     7681 tgatgatatt atcaattatt gtctatcaaa cttagatgat gttttattaa tgaatagttg
     7741 gggggaacga gcaatttact acaatcctaa tggtatttta aagcgaggag tatatgttct
     7801 taccattaaa gaaaaagaca gtaatcatga taaaggttcg ttggttagtc gcccaaatgt
     7861 ataccgtgtg aatataggat taaaaaaaga aacttttatt gaaatgtttg gatatattcc
     7921 aaaacgtcca ggtgtaggtc aaatagttga tatggatttt gattttacaa aattggacac
     7981 aatcatgcca catcctatct actcatggat gggatggata tgcgtcctaa gccctactga
     8041 aaagacattt gagaacttta aaactttaat aggagaatct tacaattttg caaaacaaaa
     8101 atttaaaaag agaaaaaaca agtaaaaacg tatgaaaata atccctaaat aaattataat
     8161 aaaaatatta aggttacaag ataaaaatta atatcttaat aacatgcaaa aaagcgaagc
     8221 caaaaaatgt attatttata aggcttcgct atatctcaaa taatttattt caaatttcaa
     8281 aactatttat tctattattt cttattattt cctgttattc ctaatctatc attcatatct
     8341 tttatcattt ttctaaaacc actacctata tcatttccaa catcttcagt tccatgaact
     8401 aattttataa agtcattttg accttttttc atatcttcat cagatacctt atctaatttt
     8461 tctattctct tatctatgtc ttttactaat ctttcccctt cagcgattag gtcatcattc
     8521 attttcttta actctgtatc ttctgtttta ccatcttttt taagagatgt tacaaatgat
     8581 tgtattttat ctctactatc tttatatgca gcctttacat cacttagata tttttcattt
     8641 cctggatatt ctttatcttt aaactgatta tttatacttt ctggagtatc ataaatagaa
     8701 tatctattta gacctgctat ataatcatta tagcttgttg aataataatt catatatcct
     8761 tcattattat ttacagattc attaggattt tttcctgtat tttcacttgg tttttcatta
     8821 tttttagtac atgcagttat acctatagct aatactagtg ctaatcctac aaataaagtt
     8881 ctttttaatt tcatttttat taccctccta gatgttttat actataaaaa attttaataa
     8941 ttttctttct taatttagta tttctatatt tttatatttt atttactaaa attaaacaag
     9001 ttataattta tttttttgga aatcataatg aataaataat taaataaaaa aattataatt
     9061 ttattattga tattgattat cattcatagt ataatctaat tacttgatat taattttcat
     9121 ttgaaggagg ttatctttta tgtcttgttg taattcacaa ttttgttgta aaaataaaat
     9181 tgaatcatca tatataaaat ggcttttaga agttttaggt ccagtctttt taggctctaa
     9241 acctgctgaa ataataaata tttcgtttac tgatgtaaat agagaggaaa aaattaatga
     9301 tatttataaa tatctatata aatgtaagaa aatagatttt atagttattg ataaagaaaa
     9361 aaagggatta aaaatcttat ttgtaaataa aaaagcatta tcagaaaaat taaaatgtaa
     9421 aaaaacagta aactttttaa agtttttagg atacaaacaa aatacgaatg ttaatgctta
     9481 tttagagcat ttagtagata aacttaagag tgatgttttt cctgatgaaa taggtatttt
     9541 tttaggatat cctcttaaag atgtgattgg atttatggga tatagtaatt atgaagtttc
     9601 tatgattaaa tattggaaag tttatggtga cacaaaacaa tccgaggaca catattcgaa
     9661 gtttttactt caccgtaaga aaatgagaaa attactagac tacataagtg tagataaaat
     9721 agtaagctgt ttttaattgt atttttgtat aataataaaa atacaccctc ttttaccata
     9781 tagtttccat aataaataag ggtgtatttt ccactttaat attttaaagt attctaattt
     9841 tgattgtaca acatatcttt aatatttatt ttcttttgtt gcattccatt agacattaaa
     9901 aattcctgtg tatcttctaa ttcttttata tccttgtccg ttattttaga actaaagtca
     9961 taccaagaat acatttcttt tgtttcatct aaagataaac caacttcttt agatacaaca
    10021 tccatcactt catccttgtt ttcattcata tattttaaag tttcttcatg aaccttcata
    10081 aatcttttta ctaattcagg atatttttca gcaaagtcat cacttacagc agtaactatt
    10141 attccactta ctaatccttc tccatttaca atcattttgg cacctgaatt tatcgttttc
    10201 aatgccactg gacctgcaag cattgctaca tcagcacttt tactttctaa tgcagaagca
    10261 gcactaggaa tatccatatt tacatattca acatcatcta tagtatagcc ttctttagca
    10321 agtgcagcaa tcaacagttg atgaagtata gtcccttttg gacctacaat ttttttacct
    10381 tttaagtctt ttatagattt aatattatca ttattagtta taagcatata tccttttggt
    10441 gaacggctat aaatattcgt aattttaaga ccaacaccat ttgatgcagc tattattgca
    10501 gacgttcctc ctaatgcatg taaaaagtct agctcacctg ctgctaatgc ttgagtttgc
    10561 tctggtcctg ttgtcaattc atggaaattg acttttatat tgtccttttt aaattccttt
    10621 ccaaataaat catccttttt ttctaatata ctaggaacat taagtggtga ttttacataa
    10681 gttaaattta tttccttagg taaactagcc tctttttttg caggttcatc tttcttatca
    10741 tttgttgttg aacatcctac agtcccaacc aacaccatta ttaaagatgt cattactgct
    10801 aaaatctttt tgtttctttt aatcaattaa aactccccca attcccttaa tatttctttt
    10861 ttcaagttta tataatagtt tttagttaaa tctctattat attcatcttc gacactaaat
    10921 tgtttaatcc ttttattttt actaaaaaca attattttct ttgctatttc catagcttct
    10981 tcaatattgt gagttacaaa tactacacct tttttagtat ttttatggat atttacaact
    11041 tctttttgca tttttcttct tgtgaagtaa tctagtgctg caaatggttc gtccatcagc
    11101 aaaatatcgg gattgaagga aagtgctctt gctatactta ctctgtgagc cattcctcct
    11161 gataattcat ttggatatga gtttttaaac ttttcaagct tcatcatttt taaatacttg
    11221 tctaaatcaa ctttatttct attatctttt tcagtatgta aaagtatatt ttcacttaca
    11281 ttcagccatg gcataagtct actttcttga aataccattc ctacttttgg agtacacttt
    11341 ttatcattat taaaaaaata tatgtttcca ctagtagcat tttcaagccc tgctaaaatt
    11401 ctaagtagcg ttgttttccc acatccactt tcacctaata taacagttat ctcttcacta
    11461 gatatattta aagatatatt atcaagaact aaatgctctt tattatcaac taaatatttc
    11521 ttatatatat tctctagcaa aaatccactt ctaaccattt aaatcaacct gcttcccttt
    11581 gctaaatttt gttattatct ttgaaaatag ataatctgaa agtataccta aaaatccaat
    11641 aacaaaaatt cctaccaata caacatcagt tctagacata tcttttccat cagaaatcaa
    11701 atatcctagt cctgaagaag ctgcaataag ctctgctcca attatagccc taaaactata
    11761 cccaagccct aaactaagtc caacaacaat atccagcata gaattaggga ttattatttt
    11821 ataaaaaatt ctctttttag ataaattaaa agatttacct acttctatta atttattgtc
    11881 acaatttttt atacctttca atgtatttaa aaatattgga aaaaaggatg ccaaaataat
    11941 aattataatt ttagattctt cacctatacc aaaccataaa ataagcattg gcaccaaagc
    12001 tagtggaggt gtacttcgca taaattcaaa tagtggtttg aaatattcat acattttttt
    12061 atttactcca aataaaactc caagtggtat agccatcaat gaacttatta aaaaacctat
    12121 taatatcctt cttacactgg cataaacatt taagaaaata gaaccgtcat atatcatttt
    12181 tataaaagta tctaagacta tttcaggagg aggcagaata tagctactcc atatacccaa
    12241 aacacatact atcttccata aaattaaaat tattaaaaaa atataatatc ctttaagcct
    12301 tttatgaatt ttctcaaaca tataaaactc cttttaacat atctatccct gctacccttt
    12361 ttatttttta atatcttaaa taataattaa gctatatcat aagatttaat ctatgccaag
    12421 tcttaatcca cctgaactca ttctatcaga aggtgtagaa tctgttttta agccagacaa
    12481 tctttcagat ggttgtataa tgactatttg tccaggttca acaaattcca tatgataaga
    12541 ttctcctgaa gtctgaccaa taaaagtctt ccatgatagt tttgatactt taggatatgg
    12601 ttctcttcca gtccaagcta ctaatgcatc tgggtcaaca caacaaggtc cttcaagaat
    12661 tagaggatta ccatctgtta ttatagcaac atcttgattt tgacctgttt tatttactaa
    12721 atgtgtagta aaaagacctt tttgagatat tacccctgaa ccaatcaatt ttacactgta
    12781 atttaattgt tcagaaaatg ccaataagtt ttcactctca acataaatgg aatcacctgg
    12841 gtcaattgat attacatcta catggtaagc attttgagct aggtaaattt caccttcacc
    12901 ttcaaccacc attattggca tttgttctcc tgtcaatgac ctctgaacat gacctaataa
    12961 tgctcttccc aatccaccgc cattacttgg acctaacagc aatttttcaa aattaaaatt
    13021 tcctttaaag gctaccatag cacctttttt tgcaaaaaat ttaccacttc cccttgctat
    13081 acacataagc tcgtttgtaa catcaaattt aaacataata ttcacttata ttgcttaatt
    13141 tagcaataat ccctcctaat catatattta tatataatta tacagtaaaa ttacagcata
    13201 gtctaaccta cttcaaatat gaaatttgtt atttatacaa aaaataagaa cctgataata
    13261 aagcaattta actttttatc aggctcttat cctatttatc tcttagcgct atgacaactc
    13321 ttactacttg agcatccaga acaaccacat ccacaactgc taccattctt ttttgaattt
    13381 ttaaccatat acattacagc tagtgccatt aatactacta caatagctgc tataataaat
    13441 gtagccatat tcatcactcc ttatttatat gaattaattt ttcatataac ttaatttacc
    13501 cattttttct tttttcatat ttttatttga ataagttaaa actacaaaga ctactgctac
    13561 tgctataaat atagatatta ttgccccagc aatacttcct ccagtaccta aaactaaact
    13621 tccaacttga tttataagaa gagcaattat atacgctgtt aaagtttgga atcctaatgt
    13681 aatccatgtc catttccatg aacccatttc tctttttatg gctccaatag ctgcaaaaca
    13741 aggtgcacaa agcatattaa atgccataaa tgcaaacgca ctagctactg taaacatgct
    13801 tgcaactgaa gcaagaagtg ttgggtcttg ctctgttgca tctgatatac caaataaaac
    13861 tccaaatgtt ccaactacat tttccttagc tactagacct gtaactgttg ctactgatga
    13921 ttgccaattt ccaaatccaa gaggagcaaa tattggtgca actatatttc ctaagctagc
    13981 taatatacta tctccagcat ctaccatttg taatgaccaa ttaaatgatt gtaagaacca
    14041 gattactcca caagcaacaa atataattgt tcctgctttg attataaatg cttttcctct
    14101 atcccacata tgtattaaaa caccttttgc acttggaata tgatattgag gtaattccat
    14161 aacaaatgga gatggttctc ctgcaaataa actagttttc tttaatataa ttccacaaat
    14221 gattatcatt gcaataccta agaaatacat tgatggagct acccatgaag cacctccaaa
    14281 taatgcccct gcaaataatg ctattattgg aatcttagct ccacatggaa tgaatgtagt
    14341 taacataata gtcatttttc tatctctatc attctctata gtacgagttg acataactcc
    14401 tggaactcca caacctgaac ttataagcat tggtataaat gattttcctg aaagaccaaa
    14461 cttacggaaa attctatcca ttataaaagc tacacgtgac atgtacccac aatcttctaa
    14521 tattgataat aataagaata aaagcatgat ttgtggtaca aatcctagta ctgctccaac
    14581 tccaccaatt agaccatcaa ctacaagtcc ttgtaaccac tctgctacat ttaaagaagc
    14641 tagaaaatta cttacattgc cttgaataat ttctccaaac agtacatcat ttgtccaatc
    14701 agttgctata gtacccaatg aacttactgc tatatagtaa actccccaca ttataagtgc
    14761 aaaaataggt aatgctagta tacgatttgt tacaatctta tctatcttat ctgatacagt
    14821 ttccttacct tttcgattct tctttattat acttgaaatt attgaactaa taaattcata
    14881 acgattggct gttattatac tttcactatc atcatccaat tcatcttcac aatttctagt
    14941 tatttcttca atactattca atattgtttt agaaatatca agtttttgta taacattttc
    15001 atctctctca aatagcttta tagctaacca gcgtgtttct acatctatat atggagtctt
    15061 ttcttctatt attttttcaa ttttttctat tgcatcctta ctttcatcaa caaagggtaa
    15121 tttgaaattt aatttattgt tactacttgc aagttcaact gccttttcag cagcctccat
    15181 aattccttga cctttaactg ctgttacttc taccactggg caacctataa cttcagatag
    15241 ttctttaata tttatcttat caccattctt atttacaata tccatcatat taagagctat
    15301 aacggtcggt atacctagct ctaaaacttg agttgtaaga tataaatttc tctctatatt
    15361 tgatgcatct acaatattta ttactgcatc cggcttatca tctagcataa aattacgtgt
    15421 aactacttct tctaatgtat atggagataa agaataaata cctggtaaat ctactatttc
    15481 cacatcttta tttcctttta attttccacc ttttttttca actgttactc ctggccagtt
    15541 accaacatat tgtgatgagc ctgtaagccc attgaacatt gttgtcttac cacagttagg
    15601 atttcctatg agacctattt ttattgacat ttccattccc tccattatta tttaaataca
    15661 tcactattca tgatatagaa aatcattctc attatataat tacattaact ctactctaat
    15721 taatctttat tattccacaa taattttttc tgcatctgac ttacgaattg atagttcata
    15781 atctctgact gttacctcaa ttgggtcacc aagaggagct acttttctta taaatatatt
    15841 aacgcctctt gtaatcccca tatccattat acgtcttcgt gtagctcctt ctccttctaa
    15901 ctttttgact tttacagtct ctccacactt aatatccttc agtctgttca tgtcattacc
    15961 tccctatatt attattctac ttgccatttt tttatctaat gcaactctag tatcttttac
    16021 gtctattatt aagttaccat ctatcttaga aactatttta acatttgtac ctactacaaa
    16081 acctatacta tttaaaaaag tcctcgtctt atcacttcct gaaattttct ttataactac
    16141 ttcttcacct gtatttgata gtatcaatgg catcatataa tatccctcct cttaaactaa
    16201 tttaaatcta caagcaatcg ttatcttata tataaattac aataccttaa atcttaatct
    16261 attaaaataa tatcctattt tttccttctt tttacaattc ctaattttga tttaagtcta
    16321 tcacaatagt atattttttg caagtgatta ttgtattctt ttgatttttt ttctcatttg
    16381 atttatttta ttaataaaat cgtaaaaatt aatacaaaaa taaagatgct ctaaaatagt
    16441 atactcaact aatattaaag cacctttatt atatatatca ttacttacac attgctttat
    16501 tcttttttaa aagcaatttt ttcaaactct tttacaggca ttggcttaga aaacaaatat
    16561 ccttgtacca tgtcacaccc aatttgcttt agaaattcta cttgcgaaat agtctctaca
    16621 ccttctgata ttactttcat tttcaattcc tttgccattt taatgacatt agatataaca
    16681 attttttcat tattactctc atctttttct gtaaaaaatg ctctatctag ttttaatatg
    16741 tcaacaggca attcttttaa aagattaaga gaggaatatc ccgtaccaaa atcatccata
    16801 gagattacaa atcccttttc tttcaaattg ttcattgtat caagtaaccc ttctatatta
    16861 tctaatactg ctgtttctgt tagctctaat tctataagtc ttgtcggaat tttgtattta
    16921 tctacaatta atttaaactt ctctataaaa ttactattta caaaatgcat tcgagacaag
    16981 tttacagata taggtactac tttttgtcct tcatccatcc attctctaat ctttttacac
    17041 acttcctcaa atacatagaa atcaatattt acaataaaac cattcctctc aaatacagga
    17101 ataaattcta ttggtggtat tagacctttt tgtggattat cccatcgaac aagagcctct
    17161 gcccctataa tttgataatc tgaaagacta tatttaggtt gaaaataaac aataaattct
    17221 ccattattaa gagcatctac cattgaattt tcaatttctt tctcttttaa tattttttta
    17281 tgcatttcct tatcgtaaaa agcaaatgaa tttttatgac caccttttat agtttttctt
    17341 gcagtattag ctctatccat aatagtattt atgtcattat cacttttact tattttatat
    17401 ataccacaat ctaaaatcaa tttataatag tttattttag gattactaag tatttgaacc
    17461 ttattgtaaa tattgtttaa ccttgtttta atatcatcat ctgtcttata cttaataaga
    17521 agaacaaaat ggtcagcaga aactcttgca aaaatttcat cttcctttaa ttcacttgca
    17581 atagtatttg atatatgtat caaagtatca tttcccatat catatccaaa catatcattt
    17641 atatatttaa atttgtcaac atctatataa aacaatgcat attcttctgg attattttta
    17701 gcaaacagtt tattcgaatt tattttaaat ttatctatac tatctgctcc tgtcaatggg
    17761 tctgtatatg ctatcttctt tagataatcc tctttcttct ttttattata aattatatat
    17821 ttaatagcaa ttaagaataa aatacataca aaagaaataa tttgtattga atattcttta
    17881 aaaatcacac caaatggtac tttataaggt ttgtcaatag tattagaata tatacaatca
    17941 cttaattctt cttcagtaat tttgtctatt gatttattta aaatagatac taatataggg
    18001 tcagttttat ttgatacccc tatacgcatc ccatagcttg tatctaaaac agatataaca
    18061 gataaattct cactctttcc ttctcttaaa agttcatcaa actgataaga actaagtatc
    18121 attaagtttg ctttaccttc atttatagcg tttagacaac tttctatact cttataagat
    18181 gttgtcttag cattttcaaa acttttttct atataagaat cgatagactt ataactactc
    18241 gttaaagcaa tatttaaatc attattgaga ttggtatcca gttttcctac cataatcatt
    18301 ggaatattta tgtatggatt tgtcaatttc atattaaatc gttttgcctt atcattttca
    18361 ttgattgagc cacatagcat atttgcctta ccacttttta tgtaatcaag actctcatta
    18421 taattttttg ttttaatata ttcaaatttt ataccacatt tttttgatat aattgacatt
    18481 aaattggaac ttataccttt aaacgaattg ctttccttat cataatactc tacaggagac
    18541 cactctgaat catataccat agtaagtttt gggtttgctt taataaaatt catttcttgc
    18601 cgagtaaatg ctatggaatt attgacctct cttttgaaat attttttata taattccaac
    18661 tcataataca tatcatttat ttttaattct tttaaagcat aatctaattc ttttaccaaa
    18721 ttaggtttat attttgcagt agcaaaataa aaaggctcta ctgaaaattt gctaactatt
    18781 ttcattcctt tagcatttat aatacttcca cagacaaatg catctgcctt tttttcattg
    18841 acagactcaa ttaattcatc aatagaatta cagtagatat attcaactga aaaattattt
    18901 tcttctctat acttctcaaa tgcaatatta tgaaagtttc ctctaagtac agctactctc
    18961 attcccttaa aggaacttat atcttcataa aacatattat tgttactatc ttttgtatat
    19021 agtacactat attcatatcc tgaatttagt ttaggaaaat taaatagttt atttctttca
    19081 tcattcttct gtaaaggtcc aagtaagtct atttcacctt tttctagtct gtctaaacat
    19141 tcttcccaag acccttttac aaattcatat tcccatcttg tatattttga gatttctctt
    19201 agataatcat aaccatatcc tgtataagaa tgctcttttg atgaggatat tattccgtag
    19261 tcatcacaat atccaactct tatttttttt gaattttcag actcatcagc aaagcatagt
    19321 atattgttaa aacatgatat aataagtaaa aatatcaaag aaagtatcaa gaagtgcttt
    19381 ttaaatgctt tcatatttaa aaacctccaa tttgccaact tactttaact tatttggttt
    19441 tctagttgta actactttta ttgtaatggt aaatatatca aattgcaata ttctcatata
    19501 atattcttat tcaactataa tgaatttatt attatctatt taaatacact atctaatatt
    19561 agtttcttat aagtcataaa agcacaacta acactataat tctagtgatt aattttattt
    19621 caaaaaatat aataacacta ctaatatttt aaatatcaat agtgtcataa aaacttttca
    19681 gattaattaa atctttctat atattttata ataatctaaa tcatgctaaa tatttagaca
    19741 gaaaactttt ttctttaata gtaaatactt ttgtttgaat atcagaataa ttatttgaat
    19801 atctatctat aaaaccatga tttgcatcta aaatctcaat ttggatattt tgtttcctag
    19861 aaagttggta agaaatagaa tcaacatcaa atgaatcgtg ctttgcaaat actaataagg
    19921 taggacattt tggaattaca tccatgtaat ctcgaatccg agagccataa caacaaatta
    19981 tgccatcaca aaaagaatct tcactgcatc tccatgcaat agttgctccc acactatacc
    20041 cagcaacaaa tacatattta tactctgatt ttaaatcatt tataagcttt tcaacttttt
    20101 tataaatatc aaaaccaaca ttatttataa aaaaatcata tgcctcttgg acttttgaat
    20161 atggaaaaac tcttttttct cccagaagtt caggacaaaa tacatcatat ccatatttat
    20221 aatacttttg acaaacatct tctataaagc tattaatccc atagatttca tgtaaaacaa
    20281 caatagctac ataactttta tgtatatact ttatcagatt atccaccacc tttacaaaac
    20341 agcaaatttt ttatacttag tttaatatat tcttctttac atgtcaattt acttttctaa
    20401 aatcaaattt atttttggat taatcattta tttttaaaag ttgtgcatta ttactattaa
    20461 attattctct attattaaaa atataatcgt tagaaataaa aaataaagta caaataatta
    20521 aaaaatatct cactcataac tttaaaaatt gtaagtgaga tactcctaaa atctacttta
    20581 tattaaattt attttccaaa atatctattt aataatccta agaatgcttt accatgtcta
    20641 gcttcatctt tacacatttc atgtactgta tcatgtatag catctaatcc taattctttt
    20701 gctttcttag ctaattttaa ttttccatca gttgcaccat actcagcatc aactctaact
    20761 cttaagtttt cttttgtatc tgcaactaca acttctccaa gaagttctgc aaatttagca
    20821 gcatgttcag cttcttcaag agctattctc ttataagctt ctcctacttc tggataacct
    20881 tctctatcag cttgtctact cattgctaaa tacattccta cttctgtaca ctcaccaaca
    20941 aagttagctc ttaatccttc gattatttct tcatctacac cttgagctac tcctattctg
    21001 tgctcatcag cccaattttt ttcgcctttc atttcttcaa atttatcagc tccaacttta
    21061 catactggac attgtgctgg tgcagcatct ccttcatgta tatatccaca tactgtacaa
    21121 acaaatttct tcataattac tttcctccta aattttatat atcaaattaa attttttatt
    21181 tattaagtta gtctatatat acccgcacca tataccttta aacaattttt ttaaaagttt
    21241 tttctaaata cttattttcc ctgtgtcaat aatatgtttc tataataatg tccctttaat
    21301 tttatcaatt ctttatgatt tcctgattcc acaattctac cattttctaa aactattata
    21361 ttatcacaat ttgatatggt acttaatcta tgagctataa ttatacttgt ctttccataa
    21421 gttaaattat ttattgcttc ttgaatttta gcttctgttg ctatatctat gttacttgta
    21481 gcctcatcca aaataagtat tggagcattt tttaatactg ctctagcaat acttattaat
    21541 tgtttttgac cttcacttaa atcttcaccc ctatccgata atacagtact atatccttca
    21601 cgcattttaa ctataaattt atgtgcattt gctattttac tagcatatat aacttcttca
    21661 tcagtagcct ccagatttcc ataccttata ttttccataa ctgtatcatt gaatatataa
    21721 ccttcttgtg gaactactcc aaaacaagtt ctcaaatagt ttctgttaat agagtatata
    21781 tccttaccat ctaaaaatat acttccttca tctatatgat aaaaatttgt aattagattt
    21841 ataatagttg tttttccact tcccgtctct cctatgatgg catttgatgt gccagatttg
    21901 atttttaggt ttatattatc taaaattttc ttttttgaat cataagaaaa acttacatct
    21961 ttaagctcaa tttctccctt tacaaaatga gagtttaaat taccatcttt attatcgtta
    22021 atctcacttt taaacatgtt atgcacttct tgctcttctt gttcatctat aatttcaaaa
    22081 actctttcac atccagctat ggctgaaagt aatgtattaa atagatttgc taattcattt
    22141 aaaggtcttg tgaattgtct tacataactt aaaaaactag ctataacccc tatggttata
    22201 atatctttag atgcaagaat gcctcctata atacatatag ttgcaaatcc tatattacta
    22261 atcacattca taataggcat taaaagagaa gtgtaaattt gcgatttaag ggaaatattt
    22321 agaagtctat cattgacttc tttaaaatca tttacagatt ttctttcata attaaaagat
    22381 tttactacat ttatgtttga tatcatttct tcaatatgtg catttagttt tcccaactca
    22441 acttgttgtt gcttaaaaaa aactctagtt ctctttgcaa taaaattact cacaaacatt
    22501 actatcggta ttaatattac actgcaaaag gttaaaattg ggcttaatac aaacatcata
    22561 ataaaagtca tcaatatgtt taagattcct gtaattaact gtactaatga atttgatatt
    22621 cctgtactga tattatcgac atcatttgtc actctactca taatatctcc agtagaactt
    22681 ttatcaaaaa aggttattgg tagattttta aattttaaaa ataaattact tctcatttct
    22741 ctgactatac tttgagataa tctagctgta catattccct tagacagttt aactgaaaac
    22801 tcaattatat aaaatgaaag taaaataatt attcctttta agaaaatgga ttttgaataa
    22861 gtatcgatat ctattatgtc aactaccttt ccaatagtat atggtattac agttgatata
    22921 attgaatcaa ttattactag caaaaaaata aatctagtaa tcttcttatc ttttttaaag
    22981 tacataaaaa ttcttttaaa cgttttttta aaatctttag gcttttcttt tttctttaat
    23041 ctactgacct tctgatttcc agtacttaaa ttcaatatac ttcctcctta atttacatct
    23101 tcacttacta aattttgcaa cgcaaaaatt tttttataaa ttggagaact aaccagtaaa
    23161 tcttcatgtg tagcaaatcc aaccacctca ccctcatcca agactaaaat cttatcacag
    23221 tcaattatag aactaatctt ttgtgaaata gttattacag tacatttctt actttccttt
    23281 tctcttaaat tacttatata ctcttttata ttctttctta taattgtctc tgtattaata
    23341 tccattgcac taaaacaatc atcaagaatt aatatttgtg gttttttggc tatagctcta
    23401 gctatagtaa ttctttgtct ctgtcctcct gataaatttt tacccctttg gaataaaact
    23461 tcatcataag tattttcgag ttttgttata aattgatttg catttgctat ttcacatgat
    23521 tttacaacat cctctttgca tatatctcta tttcccataa ctacattctc caatatactt
    23581 tttccaaaca cactactatt ttgaaatact acacctattc ttgcccttaa actttcttca
    23641 gaaatactgt atatactacg tcctccaatc ttaatatcac ctttatcaat tatatataat
    23701 ttttgaatta aatttactaa agaagtcttt cctgaaccag tttgaccaat cacaccaata
    23761 ttttgacctt cttctatttt aaaggatacg ttttttaata ttttttcatc tgtatttttg
    23821 ttatacgaaa aatctacatt ttcaaaaatt atatcacagt ttacaaactt taaatctttt
    23881 tctccaacat ctaaactttc ttctctctca attacttctt cattctcatc aaccaaaacc
    23941 tcacttattc tctcataaga tgcttttgcc ctaacaaaaa cattaaaaac atgtgaaatc
    24001 attataagag atgttaatat tctagtcata tagtttacat aagcaactat aatcccaatt
    24061 ttaatttctc ctgaataaat taaatgcctt ccaatcagta atattattat tatggaaaca
    24121 ttaatgatta ttgtaattgt cggtctaaaa aatgacatca tagttgtagc ttttctacta
    24181 tttttaaaaa gttcatcatt taactcttca aagctttggt tctcataatc gtatctacaa
    24241 aatagtttaa ctacttttat tccacttaaa aactgtctta attttgaatt tactttatct
    24301 gtactttctt gtacattttt aaataatcta taccctatct tcatattaag caatattata
    24361 ataaatataa ttaaaactgc aattagaata attattgaca tctttaaatt taattttata
    24421 gctataatta aacttcctat acacattatt ggtgacttta taaaaactct catcattcca
    24481 ttaacgaatt gttgcatttg attgatatca ttagtaattc ttgttattaa tgaagctcta
    24541 ccaaatttat ctatttgttt taatgagtat gtatttatct tttcaaatac atcctgtctt
    24601 aaatcataag aaaaatgctg agaaactctt gccgagatta cacttcttat tattgcaaat
    24661 attgcaccta aaaaagttat acctatcatt atagctcctg ttgatagtat gtagtctaag
    24721 ttcttatttg aaacccctat atctattatt tttgccatta tagttggttg agctaaatca
    24781 caaaaagctt ccaatgttaa aaaaaatact gctgttagaa ataatactat atattttttt
    24841 atgtattttt taaaatacct cattcaatca tcccttcata gaattttctc attaccaaaa
    24901 gtatatcata atggctaatt taattgatta tatcaattat aaat
//
LOCUS       DAMJVG010000058        24279 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.058, whole genome shotgun sequence.
ACCESSION   DAMJVG010000058 DAMJVG010000000
VERSION     DAMJVG010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24279)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24279)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24279
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.058"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            71..892
                     /locus_tag="PC512_002534"
     CDS             71..892
                     /locus_tag="PC512_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HDF2442269.1"
                     /translation="MIKKEISNFRGSSDYVVSPELMASVNVAIALEKPLLIKGEPGTG
                     KTMLAQAISNELKKDLVIWNIKSTTKAQEGLYVYDTVQRLYDSQFGGEGVDDISKYIK
                     YGKLGEAFSSNQQVILLIDEIDKADLEFPNDLLWELDKMEFYINETKETVRAKQRPIV
                     IITSNAEKELPDAFLRRCIFHYIEFPDRDMMEEIVKVHFDKVEEHLLEQVMTTFYWIR
                     SLKDIQKKPSTSELIDWIQALTLSGMPIEKIEKEVPFAGILLKNNEDIESMQRHL"
     gene            913..2109
                     /locus_tag="PC512_002535"
     CDS             913..2109
                     /locus_tag="PC512_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HDF2442270.1"
                     /translation="MFIEFFYLLRSRGLNVSLNEWMTLIEALDKGLCYSNFSNFYYLC
                     RMILIKSESDFDKFDAVFLEYFKGIEHQEEIPEEIMNWLKKPDIDLEEFERLEQNPNI
                     NLDKLRAKLEERIKEQDSPHNGGNYWIGTGGTSELGHSGKGQTGIRIGGNSTYGRAVL
                     EVAGERKYRDFRDDEVLNMRQFQVALKRLRQFSTRIDAPKTELDLDKTIEETCNNAGY
                     LKLFFEKPRKNTVKLLLLMDSGGSMRGYSTLCNTLFQSVSKSNHFKDVKIYYFHNCIY
                     DRLFTTPECWLSKSINTEWILKNIDKNYKVIIVGDASMSPSELLHIGGNYRGPYNYTP
                     GIEWLKRFKRKYSKIVWMNPELRDGWDSINYWYQTQRMIQSEFNMFPLTVKGLEKALK
                     NLMVSR"
     gene            2276..5674
                     /locus_tag="PC512_002536"
     CDS             2276..5674
                     /locus_tag="PC512_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HDF2442271.1"
                     /translation="MIIINYELIVKYNGDILRLEEELGVSVEILNSSYAIITSSNEED
                     VNILLTYPEIEFIEKPFILQTQDVQSFSSTGITGFKNRTGLTGKGTIIGIIDSGIDYT
                     LPVFRDSDGRSKILYYWDQSIQGNPPEGFREGTLYTNEDINNAIDGSMYIPISTTSLH
                     GTHVAGICATIASDARIIVVRVGNIQTDIFSRSTEFMRAIKFILDRALELRMPVTLNI
                     SYGSNEGSHRGTSLFEQYIDDMCLFWKNNIVVAAGNNADKGGHKRIRLQNNITEEVEF
                     IVGEGERILNINIWPDFVDDFSVHLVNPSNNQTQAISLTSGEIRNTLGETRITGYFYP
                     IAPYSLTRRVTLQLSSNTQITPGLWKIVFEPIDIVTGNVNIYLPTSEGLNRNTRFLIP
                     TQELTVTVPGTASRVITVGSFNSRTDIVSIFSGEGDTQLGVFKPDLLAPGEDIVSFLP
                     GGTSGALTGTSMATPHVTGVCSLFMEWGIVNGNDLFLYSQKLRALLLKGARRLSNQSY
                     PNNSSGFGFLNLSDIDLYTLSNINQDLETEDIGYRSINKSFKDEENSYKFIDGYNMQI
                     HNDLENEIYISKNASRQSGILSGIDIVHTPEFEEELAGLGMSQRFFKISDSLGVLSIN
                     NTDYNSIQRVLQLPSIIRTVSTTKMTLLGEINRGTFGGVVATEEMGVNFFKNNPNINI
                     TGRGTLISIADTGIDYLHPDFIYPDGTSKIVYLWDQTKEGTPPDGFYIGTEYTREDIN
                     RAIAENDPSLSQDEVGQGTMLSGICAGLGNVNSEYAGIAEDSELIIIKLGKIDDFYNS
                     AMLFAASQYAYKKAFELGRPLVINMSLGTSSLAGLTNRSNSEKAFFTRGLCITAGAGN
                     EGNTQTHTSGIIPYVGGSVEVELELNEDEEELSLELWLNRPDKADVIIVSPTGEESKS
                     VGISNYNKVTGLFDLEGTEYSITYIYPTTFSGQQFTNVTLKNAKRGVWKIRLVGVYII
                     TGRYNLYLPNRELLKSGTRFREVDPFYTINYPAIQDDLITIGAYNTINGSLWQSSSRG
                     PTIEDRLKPDIVAPGVNIIAAYPGNTYATITGTAAASAHAAGAAAMYFQYTFVDGRYP
                     NQAYVQKIKTFMQAGARKDSNTVYPNTNSGYGLLDVRGMFDVLR"
     gene            5684..7357
                     /locus_tag="PC512_002537"
     CDS             5684..7357
                     /locus_tag="PC512_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HDF2442272.1"
                     /translation="MEKSYCIIYQGDIESALQENGINRYMVLNSQLAVIYVPLDFDET
                     ILNNIIQVAWWEESEPMSSLIEITNNVNNGETITTAAETDYIYENPYNDITGRGILLA
                     VIDSGIDYLHPDFINDDGTSKVLYLWDQEANTNPPPEGFIFGSEFTRSELNIAINRND
                     GSLSQDNIGTGTLVSGILVGNGRINSQYRGITTESDLIVVKLKSYTDTYYAGRINYSV
                     SDFLAAITYVTNIARTENKPLIINLTIGVKSSAVATTSILDTFNILSSAGVVVVSGAG
                     NQGNTDIHYSGRFSSVGEVQDVIIQDGDDYALDITLNTNGPDKVGAQIISPSGEVSHD
                     IRYSPDFYIYRGKFNLENTTYAMRFIYPYITSGKENLEIRLRDIKPGVWILRLTSELI
                     INGEYDIYLPNKNLIAPDTRFLDPDSVATITMYAASDDVITVGTFNNKTDSMWIGSSK
                     GPIRGRGIKPDIVASGVDIISTYKNGTYNTGTGTGVSSSIVTGVLALLMEYLEKQDNV
                     PRLSLFTQVLKTYLILGATKLEIYTYPNVSQGYGILNLKNTIQQIANTL"
     gene            7630..7824
                     /locus_tag="PC512_002538"
     CDS             7630..7824
                     /locus_tag="PC512_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3787 domain-containing protein"
                     /protein_id="HDF2442273.1"
                     /translation="MESKKARALKGKDNKRLKSSLLVGNESTAAWADVEKLKPHSKVS
                     IPSIKGVEEAKDWVDNGSKL"
     misc_binding    7993..8226
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            8303..9700
                     /gene="asnS"
                     /locus_tag="PC512_002539"
     CDS             8303..9700
                     /gene="asnS"
                     /locus_tag="PC512_002539"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HDF2442274.1"
                     /translation="MQKEFITVKELYREKEQYIGKTVKVAGWIRTSRVSKNFGFIELN
                     DGSFFKNMQIVFDEKVENFKEVGKLAISSSILVEGELVSTEGAKQPVEIHAKSIVVEG
                     ESDSSYPLQKKRHTLEYLRTIAHLRPRSNTFSAVFRVRSIAAYAIHKFFQERNFVYAH
                     SPIITGSDCEGAGEMFRITTMDLNDIPKTEDGKIDYTQDFFGKEANLTVSGQLNAEIM
                     ALSFRNVYTFGPTFRAENSYTGRHASEFWMIEPEIVFADLEDNMELAEDMIKYVISYV
                     LENAPEEMEFFNSFIDKGLLERLNKIVNSEFIRITYTKAVELLIESGHEFEYPVEWGC
                     DLQTEHERYITEQIYNCPVFVTDYPKDIKAFYMRMNEDGKTVRAMDLLVPGVGEIVGG
                     SQREEREDVLLDRINEMGLREEDYWWYLELRKFGTATHSGFGLGFERIIMYMTGMSNI
                     RDVIPFPRTPKNAEF"
     gene            complement(9873..11048)
                     /locus_tag="PC512_002540"
     CDS             complement(9873..11048)
                     /locus_tag="PC512_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF2442275.1"
                     /translation="MNLEKIKKFFGFPLDKKHKDNVEKELCNYLYHTGKIICIIIVIS
                     QIIMMISISAREGGPFVTPRRQWYFYMYVTLFCVSSVFMFVFSYLWNKKKDCCTFYIN
                     LWIIYVTFFCLWGCVITLLDQLGGNDLSVFSYIMLAAAAFSVLKFGESVIVFGGCFLF
                     LNLFLPGIQTIPGNEFSNIVNTFFITSLAIFVSTMLYRNRVFTYYDKLLISQQYEEIS
                     HINNLLNDKVMTDDLTKMNNRRYLEDILQKKLISHANQEPITGMMIDIDYFKQFNDNY
                     GHQKGDYCLQNIAKVILDFTSSENEHAIRYGGEEFFICIFNCNEADAKLKSECLRKII
                     ESCNFERDDVPLKCVTVSIGVYTKKIGKTITLNEFISNCDKALYTAKEQGRNCVAFY"
     gene            11467..12831
                     /locus_tag="PC512_002541"
     CDS             11467..12831
                     /locus_tag="PC512_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HDF2442276.1"
                     /translation="MGEKKINNMNYSHNNYSKKTGEPTRKIKNSHITLKSKEEKICSS
                     CNKENNTKDNYCKFCGNELYEIASLRPLETKLDLKSKIKELSYHANKRGVFLTTFTTI
                     FILFIIALIFKAIITIQFNDISYLVNPAHIILALNLGQISVSMSTMMGSGFINANIGL
                     LILLIIPILVLLISNLIFMRKRCRDSKTVLANSLGVGIFYGLVLAILSIFTNVKTSSH
                     SMLEYGYALEYSYEFFSVLLNGFVLGFICTYITTYKKSYEKENMYLSLFSNSIRTFIL
                     GYVLVLVILLVLTISDSSYLNELDMSSYSNGLNLFTILPQIASYMWAFANGISVTIIN
                     STVSMFTLSSSSLFGDTKLMFYAMGALSMLILLLNGYKLRFKYNTDSIRPIIVFSIYY
                     AFLMGILALFSTFILDSNINFFNTTNYGTTLIMQFKVLQAIVISFVYSFVISLIGYKL
                     NSAD"
     gene            12853..13344
                     /locus_tag="PC512_002542"
     CDS             12853..13344
                     /locus_tag="PC512_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HDF2442277.1"
                     /translation="MEGNTNNKVDDKFSKVKKKFGSGKFKVELYKEKSKLNREIDDIQ
                     EKKAKIFLEMGILTYQKIREDSINDNSFDKFCDELLELDKLIYEKNMEINEMEMAESN
                     VTCECGYVGNVNDKYCAECGKKFELENECDDFIICGYCESEIDTEAEFCPCCGRKIIM
                     DLE"
     gene            13616..14287
                     /locus_tag="PC512_002543"
     CDS             13616..14287
                     /locus_tag="PC512_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HDF2442278.1"
                     /translation="MLDKVKGRLIVSCQALENEPLHSPFIMGRMAKAAMEGGAVGIRA
                     QGVEDIIEIKKVTGLPVIGIIKRNYEDSDIYITPTKKEVDELLTTGCEMIALDATNRV
                     RPNNEDLKELIKYIKENGVLVMADISNYDEAIKAQEYGVDCVSTTLSGYTPYTKTLEG
                     PDFVLMKRLVKDLEIPVIAEGKVNTPQDLKKVFELGVHSSVVGSAITRPQLITEKFVK
                     AIEIN"
     gene            14372..15238
                     /locus_tag="PC512_002544"
     CDS             14372..15238
                     /locus_tag="PC512_002544"
                     /EC_number="4.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003452648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HDF2442279.1"
                     /translation="MKGIYSALLVSFDKEGNINEKGLRQIIRHNIDVCKVDGLYVGGS
                     TGENFMLSTDEKKRIFEIAKDEVKEEIKLIAQVGSVNLKEAVELAKFTTDLGYDAISA
                     VTPFYYKFDFEEIKHYYNTIINSVDNRLIIYSIPFLTGVDMSLDQFGELFENEKIIGV
                     KFTAADFYLLERMRKTFPNKLIFAGFDEMMLPATVLGVDGAIGSTFNVNGVRARQIFE
                     LTKNEKISEALEVQHVTNDLITDILGNGLYQTIKLLLEEQGVEAGYCRQPMKEATDEM
                     KSRAKEIYRKYF"
     gene            15271..16773
                     /locus_tag="PC512_002545"
     CDS             15271..16773
                     /locus_tag="PC512_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003462875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HDF2442280.1"
                     /translation="MVGFTWIDFAILVVYLLAVLFAGLLFSKKEMKGKEFFKGDGTIP
                     WWVTSVSIFATLLSPISFLSLAGNSYGGTWILWFAQLGMFIAIPLTIKFFLPLYSRLE
                     IDTAYEYLEMRYESKGLRVLGALMFIIYQIGRMSIIMYLPSIVLAGLTGIPVNVLIIV
                     MGVIAIIYSYTGGLKAVLWTDFIQGMVLIVGVTGTLFYLIASINGGFGTVMDTLTTGH
                     KFLASNEVMFDKNILSTSAFIIFVGAGLNTFSSYVSSQDIVQRFTTTTDIKQLNKMTY
                     GNGVLSMGLATVFYLIGTCLFIYYTQNPDLAQTVQQDQVFASYIAYELPVGITGILLA
                     AIYAASQSTLSTGLNSVATSWTLDIQTIITKDISMEKQTKIAQYISLGVGILSIAVAI
                     VLANGEIKSAYEWFNSFMGLVLGVLAGIFVLGAFCKKATKMGAYVGFIVSAILVVYLK
                     YRMPEVTSWAYSLITITTSVVVGTIVSAIEAKVKAKVSLPKAETTVYYEK"
     gene            16903..17355
                     /locus_tag="PC512_002546"
     CDS             16903..17355
                     /locus_tag="PC512_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HDF2442281.1"
                     /translation="MIFGNINHSKTYSTLHEDLLRCFEYAKDNSLIDYEKGTYTIDGD
                     DIFVNIVEYKTCEKEDRFWEAHKKYIDVHLMLDGCERIDINFIENLEQKIYEEKGDFL
                     PLDGKNNGYMELRKGDFLVCYPEDAHMTGIKVLEKENIKKAIFKVLVR"
     gene            17515..18318
                     /locus_tag="PC512_002547"
     CDS             17515..18318
                     /locus_tag="PC512_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442282.1"
                     /translation="MENIDVFLLIGQSNARGLGNPKESIIPNENCFEYLSTDEIINMR
                     CELETSEGDGTIAPAFSNEWNKLTGNKVCFIHNAKDGSRIKNWNHDNNWFLNDTIEKF
                     NTGCTTLSKHYNIENKYVIWIQGESDAKYGSDVLYYKESLKKIAYRLKEECMIDKMFV
                     SLTGYWLGEDEYFIRTRRIAAAQESACSECDILCVGSKIAMQFHDRGLTIDDVHYTQE
                     GLNMLGEDLCKNIYKYHITKEKSVLSDTIDLSEARKYICELEKISKRFV"
     gene            18376..19263
                     /locus_tag="PC512_002548"
     CDS             18376..19263
                     /locus_tag="PC512_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDF2442283.1"
                     /translation="MKNYVCIDVGGTSIKYGFIREDGFIIDKSSLDTEAKEKGGEGIL
                     AKIKDIVKKYIEENEISGICISTAGMVDPVEGKILFALEELIPNYKDMQLKKEVEKEF
                     NIKCEVENDVNCAGLGEMWLGAGRGATSSICLTIGTGIGGCIIINNKLINGFSNSAGE
                     VGYMNVNGSSFQELASTSSLIKKVAKIKNLNENDLNGKIIFDLAKNNDEDCLKELDNM
                     IKSLAVGIANICYVINPEVVILGGGIMAQEKFLKPKIDKALKEVLIERVYKNTNIEFA
                     KRQNDAGMLGALYNFLNKI"
     gene            19282..20130
                     /locus_tag="PC512_002549"
     CDS             19282..20130
                     /locus_tag="PC512_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF2442284.1"
                     /translation="MSILEQLESPTFKVTKSDKLLIAYIKENIDDVFYKPISQIAKES
                     NIGEATITRFVKKMNFNGLQDFKVTLAQEISTINKKNIINKNIQNDEPALDTAKKLLS
                     SNVTTLENTVEIINSKDVHDCARLIINAKKVYFIGIGYSGIIAQDSNYKFMRIGLNCV
                     SFDSSHTMIMMSSIMEEGDLIIAISHSGETEEIIKTVKLARANNAKIISITENKNSEL
                     KDISDVHLSYVSGETVLETGSISSKLAQFFIIDLVYTQVVKELSNEAIERKIKTTNAI
                     KLFKNE"
     gene            20193..20882
                     /locus_tag="PC512_002550"
     CDS             20193..20882
                     /locus_tag="PC512_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HDF2442285.1"
                     /translation="MSKLKDYNIDKVIIFNNLSTKTKNQLKEKVKLKRLQKKEILFYE
                     KDSLDSVYILLEGKVSIFKISENGERKVIFILNSGEVINDITLDASKNSTVGCEAFEN
                     SIVAYYSIEEFLEIMQNDFQLTKDIISYMERRIRRLYRQLKNSISIKVDKKLAAKLYR
                     LSREFGVCCGEWTLLNVNITVTYLADMLGCKRETVSRMIKVLQKEELIKIDNKGFYVK
                     ETELSRYFKNN"
     gene            complement(21212..22402)
                     /locus_tag="PC512_002551"
     CDS             complement(21212..22402)
                     /locus_tag="PC512_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009271880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDF2442286.1"
                     /translation="MSNVKRKDSKNRNLRNGESQRKDGRYVYKYTDIYGKPQFIYAWK
                     LVPTDKTPAGKRDDISLREKEAQIKKDLDDGIDTAGGKMTVCQLYDKKNSQRKNIKRA
                     TEKGRQYLMNALKNDPLGMRAIDTVKQSDAKEWAIRMSERGYAYKTIDNYKRSLKASF
                     YMAIQDDCIRKNPFEFKLSDVLEDDTEPKVILTPEQEERLLAFMETDKIYSKYYDEVV
                     LLLETGLRISEFCGLTTHIDMQNRILNIDHQLLRDSEIGYYIDTPKTKNGKRKIPLTE
                     RAYQALQRILKNRVKAQPLVVGGYSNFLFLNREGLPKVAGNYVGMVRGLIKKYNKYHK
                     DKLPNITPHSFRHTYCTNMANKGMNPNTLQYLMGHANITMTLGYYAHGTFQSAKAELE
                     RLAC"
     gene            complement(22480..22683)
                     /locus_tag="PC512_002552"
     CDS             complement(22480..22683)
                     /locus_tag="PC512_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HDF2442287.1"
                     /translation="MNNTDVPIWEKYTLTIEEASKYFRIGEKKLRKLAEENIDAGWVI
                     VNGNRIQIKRKQFEKIIDTLDEI"
     gene            complement(23065..23313)
                     /locus_tag="PC512_002553"
     CDS             complement(23065..23313)
                     /locus_tag="PC512_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004613734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2442288.1"
                     /translation="MKHTFKKPSYYLLSQAMDGDEKAIEKVLAFYDPYISKCCLRPLY
                     DEYGNVYIVVDMELKGLIREALIKMILGFDIALEIEEE"
     gene            complement(23317..23736)
                     /locus_tag="PC512_002554"
     CDS             complement(23317..23736)
                     /locus_tag="PC512_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005361151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF2442289.1"
                     /translation="MKPSDFQKTVQCRFESCLKKVVRHVVKDYQQGLKRRKEKEISFC
                     ELPEIMVENLAVWDDYETDYTIFNVCGNDIRVYDDELAEALKQLSERNRETLLMYYFL
                     EMNNEEIAKKQNISRSGVFQNRHNSLALMRKLLKEKR"
BASE COUNT         9112 a         2913 c         4367 g         7887 t
ORIGIN      
        1 atttttatat caaaaatagt aataaagtct atatacattt agaaaatact gtttaaaagg
       61 agtaggattt atgataaaaa aagagatatc taactttaga ggaagtagtg attatgtagt
      121 atcaccagaa ttgatggcat cagttaatgt tgctattgct cttgaaaagc cacttttgat
      181 taagggcgaa cctggaacag gtaaaactat gctagcacaa gcaatttcaa atgaattaaa
      241 aaaagattta gtaatttgga atataaaatc aactacaaaa gcacaagaag ggctttatgt
      301 atatgatact gttcaaagac tttatgatag ccaatttgga ggagaaggtg tagatgatat
      361 tagcaagtac ataaaatatg gtaaactagg agaggccttt agctcaaatc aacaagtaat
      421 tcttttaata gatgaaatag ataaggcgga tttagaattt ccaaatgact tgctttggga
      481 attggataaa atggagtttt acataaatga gacaaaagaa actgtaagag ctaaacaaag
      541 accaatagtt attataactt caaatgcgga aaaagaactt ccagatgctt ttttaagaag
      601 atgcatattt cattatatag aatttcctga tagagacatg atggaagaaa tagttaaagt
      661 acattttgat aaagtagaag aacacctatt ggaacaagta atgactactt tttattggat
      721 tagaagttta aaggacatac aaaaaaagcc tagtacatca gagttaatag actggataca
      781 agcattaact ttgagtggaa tgcctattga aaaaatagaa aaagaagttc cttttgcagg
      841 aatactactt aagaataatg aggatattga atctatgcaa agacacttat agttaatagg
      901 agctggataa ttatgtttat tgaatttttt tatttattga ggtcaagagg attaaatgta
      961 tctttaaatg aatggatgac tttaattgaa gcattggata aaggactgtg ctattcaaac
     1021 ttttcaaatt tttactatct ttgcaggatg attttaataa aaagtgaaag tgattttgat
     1081 aagtttgatg cagtgttttt ggagtatttt aaaggtatag aacaccaaga agaaattcca
     1141 gaagagatta tgaattggct taaaaaacca gatatagatt tagaagagtt tgaaagatta
     1201 gaacaaaatc caaatataaa tcttgataaa ttaagagcta aattggagga acgaataaaa
     1261 gaacaagatt ctcctcataa tggtggtaat tattggatag gcacaggagg cacttcagag
     1321 ttaggacatt caggaaaagg gcaaactggt atacgtatag gtggaaattc tacttatggt
     1381 agagctgttc ttgaagttgc aggagaaaga aaatatagag attttagaga tgatgaagtt
     1441 ttaaatatgc gtcaatttca agttgcacta aagagacttc gtcaattttc tactagaata
     1501 gatgctccaa agacagagct tgatttggat aagactattg aagagacttg taataatgca
     1561 ggatatttaa agttattttt tgagaagcca agaaaaaata cagtgaagct tttattgctt
     1621 atggattcag gtggttcaat gagagggtat agcactttat gtaatacatt atttcagtct
     1681 gtaagtaaat caaatcattt taaagatgta aagatatatt atttccataa ctgtatttat
     1741 gatagattat ttacaacacc tgaatgttgg ttaagtaaat ctattaatac tgaatggata
     1801 ttaaaaaata tagataaaaa ctataaagtt ataattgttg gagatgcttc tatgtcgcct
     1861 tctgagttgc ttcatattgg tggtaactat cgtggtccat ataattacac acctggtata
     1921 gagtggctta aaaggtttaa gagaaagtac agtaaaattg tatggatgaa tccagaactt
     1981 agagatggat gggattcaat taattattgg tatcaaactc aaagaatgat acaaagtgaa
     2041 tttaatatgt ttccattgac tgtaaaaggt cttgagaaag cattgaaaaa tttaatggtt
     2101 tcaagataaa gtaaatataa atgatggtat gatttattca aaattgtacc atcattattt
     2161 atttttttaa tatacctatt ataaattgta taactgaaac ttaaaaaatt atatagtcta
     2221 atacatttta gactcacaca aaacatatac attaataata attttagaag tcgaggtgat
     2281 tataataaat tatgaattaa ttgtaaaata caatggagat atattgaggt tagaagaaga
     2341 attaggtgta tcagtagaga tacttaattc atcatatgca ataataacat caagtaatga
     2401 agaagatgta aatatacttt taacttatcc agaaattgaa tttatagaaa agccttttat
     2461 attacagact caggatgtgc aaagtttttc aagtacagga ataacaggat ttaaaaatag
     2521 aactggttta actggaaaag gaactataat tggtataatt gattcgggaa tagattatac
     2581 tctacctgtg tttagagata gtgatggaag gtctaagata ttatattatt gggaccaatc
     2641 tattcaagga aatccaccag aaggttttag agaaggaaca ttatatacta atgaagatat
     2701 aaataatgca atagatggaa gtatgtatat acctatttca acaactagct tacatgggac
     2761 acatgttgca ggtatttgtg caactattgc aagtgatgcc agaataatag tggttagagt
     2821 tggaaatata caaaccgata ttttttcgag aagtacagag tttatgaggg caattaaatt
     2881 tattttagat agggcattag aattaagaat gcctgttaca ttaaatataa gttatggaag
     2941 taatgaaggt tcacatagag gaacatcttt atttgaacaa tatatagatg atatgtgttt
     3001 attttggaaa aacaatatag ttgtagcagc tggaaataat gcagataaag gaggtcataa
     3061 aaggattagg cttcaaaata atattacaga agaagttgag tttatagttg gggaaggaga
     3121 gcgtatatta aacataaata tatggccaga ttttgttgat gattttagtg tacatttggt
     3181 aaacccatca aataatcaaa cacaagcaat ctctctaact tcaggtgaga taaggaatac
     3241 tttgggtgaa actagaataa ctggttattt ttaccctata gcaccgtatt ctctcacaag
     3301 aagagttact ctacaattaa gttcaaatac acagataact cctgggttat ggaaaattgt
     3361 atttgaacca atagatatag taactggtaa tgtaaatata tatttgccaa cttctgaagg
     3421 tctaaataga aatactagat ttctgattcc tactcaagag cttactgtaa cagttcctgg
     3481 aacagcaagt agagttataa cagtaggtag ttttaattca agaacagata tagtatctat
     3541 attttctggt gaaggagata cacaattagg tgtttttaaa cctgatttat tagctccagg
     3601 tgaagatata gtatcttttt taccaggagg tacaagtgga gcattaactg gaactagcat
     3661 ggctacacct catgttacag gggtttgttc attgtttatg gaatggggaa ttgtaaatgg
     3721 aaatgattta tttttgtatt cacagaaatt aagggcatta cttctaaagg gagcaaggag
     3781 attaagtaat caatcttatc caaataattc atcaggattt ggttttttaa atttatcaga
     3841 tatagatttg tacactctat ctaatataaa tcaagattta gaaacagagg atattggata
     3901 tagaagtatt aataagtcat ttaaagatga ggaaaatagt tataagttta tagatggtta
     3961 taatatgcaa atacataatg acttagagaa tgaaatttat ataagtaaaa atgcaagtag
     4021 acaatcagga atactatcag gaatagatat agtccatact cctgaatttg aagaagaact
     4081 agctgggtta ggtatgagtc aaaggttttt taagataagt gattcattag gtgtactatc
     4141 tataaataat acagactata atagcataca acgagttttg caacttcctt caatcataag
     4201 aactgtatcg actacaaaga tgacattact tggagaaatt aatcgaggta cttttggagg
     4261 tgtagttgca acagaagaaa tgggcgtaaa tttctttaaa aataatccta atattaatat
     4321 aacaggaaga gggactctaa tatcaattgc agatacagga atagactatc tacacccaga
     4381 ttttatttat ccagatggca cttcaaaaat agtatattta tgggaccaaa caaaagaagg
     4441 aactcctcct gatggttttt atattgggac agaatataca cgagaagata taaatcgagc
     4501 tatcgcagaa aatgacccta gtctatctca ggatgaagtt ggtcaaggaa ctatgttgag
     4561 tgggatatgt gcagggcttg gaaatgtaaa tagtgaatat gcaggtatag cagaagattc
     4621 tgagctaata ataataaaac tcggcaagat agatgatttt tataatagtg caatgctgtt
     4681 tgctgcatct cagtatgcat ataaaaaagc ttttgaactt ggaagaccat tagttataaa
     4741 tatgtcttta ggtaccagta gcctagcagg tttaaccaat aggagtaata gtgaaaaagc
     4801 gttctttact agagggttat gtataacggc aggagcagga aatgagggca atacacagac
     4861 acatacatct ggaataatac catatgttgg aggttctgtt gaagttgaat tagagttaaa
     4921 tgaagatgag gaagaattat cattagaact ttggttaaat agaccagata aagctgatgt
     4981 aataatagta tctcccactg gtgaagaaag taaaagtgtt ggaatttcaa attataataa
     5041 agtaacaggt ttatttgatt tagaggggac tgaatattct ataacatata tatacccaac
     5101 aactttttct ggacagcaat ttactaatgt tactttaaag aatgcaaaaa gaggtgtatg
     5161 gaagattcga ttagtaggag tttatattat aacaggaaga tataacttat accttccaaa
     5221 tagagaactt ttaaaaagtg gaactagatt tagagaggta gacccttttt acactataaa
     5281 ttatcctgcg attcaagatg atttaataac cataggagcc tacaatacta ttaatggtag
     5341 tttatggcaa agttcatcaa gagggccaac tattgaagac aggttaaaac cagatatagt
     5401 agcaccaggt gttaatataa tagctgctta tcctgggaac acgtatgcaa ctataactgg
     5461 tacagcagca gcaagtgcac atgcagctgg tgctgctgca atgtattttc aatatacttt
     5521 tgttgacggt agatatccaa accaagcata tgtgcaaaaa ataaaaactt ttatgcaagc
     5581 tggtgctaga aaagattcaa acacagtata tccaaataca aattctggat atgggctctt
     5641 ggatgttaga ggaatgtttg atgttttaag ataggaggga tttatggaaa aatcttattg
     5701 tataatttat caaggtgata tagaatctgc cctacaagaa aatggaataa ataggtatat
     5761 ggttttaaat agtcagcttg cagtaatata tgtaccttta gattttgatg aaactatttt
     5821 aaataatata atacaagttg cttggtggga agaatctgaa ccaatgagca gtctaattga
     5881 aataactaat aatgtaaata atggagaaac cattacaaca gcagctgaaa ctgattatat
     5941 ttatgaaaat ccatataatg atataacagg gagaggaatt ttattagcag ttatagattc
     6001 tgggatagat tatttgcatc ctgattttat aaatgatgat ggaactagta aagttttata
     6061 tttatgggac caagaagcaa atacaaatcc acctccagaa ggttttattt ttggaagtga
     6121 atttacaaga agtgagttaa atatagccat aaatagaaat gatgggagtt tgagtcaaga
     6181 taatataggt actggaactt tagtttctgg tatattagtt ggaaatggaa ggataaattc
     6241 tcagtacaga ggtattacta cagaatcaga cttaatagta gttaaattaa aatcatatac
     6301 agatacttat tatgctggaa ggataaatta cagtgtttca gattttttag cagctataac
     6361 gtatgttact aacatagcaa gaacagaaaa taaaccactg ataataaatt tgactattgg
     6421 agttaagtca agtgctgtag caactacttc aatactagat acttttaata tattgagtag
     6481 tgctggtgtg gtagtagtga gtggtgcagg aaatcaaggg aatacagata ttcattattc
     6541 tggcagattt agcagtgtgg gagaagttca agatgtaata atacaagatg gagatgacta
     6601 tgctcttgat ataacactaa atacgaatgg tccagataaa gtgggagcac agataatatc
     6661 tccttcaggt gaagttagtc atgatataag gtattctcca gacttttata tatatagagg
     6721 aaaatttaac ttagaaaata ctacttatgc aatgagattt atttatccat atattacctc
     6781 tggaaaagaa aatttggaga taagattaag agatataaaa cctggagtat ggattttaag
     6841 attgacttca gaacttataa taaatggaga atatgacata tacttgccaa ataaaaattt
     6901 gatagctcca gacacaaggt ttttagaccc tgattcagta gctactataa ctatgtatgc
     6961 tgctagtgat gatgtaatta cagttggtac atttaacaat aagactgata gtatgtggat
     7021 tggttcttcg aaaggaccaa ttagaggaag aggaattaag ccagatatag tagcttcagg
     7081 tgtagatata atatccacat ataaaaatgg aacatataat acaggaacag gaacaggagt
     7141 gagcagttct atagtcacag gtgttttagc cttattgatg gaatacttag aaaaacagga
     7201 taatgtaccg agattatcat tgtttacaca agttttaaaa acatatttaa tattgggtgc
     7261 tacaaaactt gagatatata catatccaaa tgtatcgcag ggatatggga ttttaaattt
     7321 aaaaaatacg attcaacaga tagcaaatac tctatagata agaacctatg taaaattata
     7381 attgattatt agtttaattg tatcaaatac tttagataga gtagaaaaat agcataaaaa
     7441 ataaatatga aaattaaaaa acagttttat attttgaata cacaaagtaa atattttgta
     7501 tataaatagg tataaattaa gtattgaaaa gatatgatgt taatttaaaa ataattataa
     7561 tttagactta tgaattttat ttgtaaaatt gctaaaacta ttacaaaata aataatagag
     7621 gtgatagttt tggaaagtaa aaaggcaaga gcattaaaag gtaaagataa taaaagactt
     7681 aaaagttcac ttttagttgg aaatgagtcg acagcagcat gggctgatgt tgaaaaatta
     7741 aaacctcata gtaaagtttc aataccttca attaagggtg tcgaagaagc aaaagactgg
     7801 gttgacaatg gaagtaaatt ataaaatttt ggaaattgaa gtaataaaga agtaatgaag
     7861 ataagtattt attatcatta tgtaaggtag aattattata ttttaaataa caatcagtat
     7921 caattatata aatttattga ctaaaaattt ataaattggt ataattttgt taattagcag
     7981 aaataataaa agataaatac tgtgaagaga agagtagata taaaatgtag ttctagcgag
     8041 ttgaggatgg tgaaagctca atacgaggtt tatattgaag aacatcttgg agtttctaat
     8101 cgaaagctta tttagtaagt agacttagac ggaaggcacc gttataggct ttaagcattg
     8161 cttaactaag aggtcattat gacaactagg gtggtaccgc gagagtaata gtctttcgtc
     8221 cctttatata gggatgaagg gcttttttta ttgaaattat atttaaaaga aattaataac
     8281 aattatacta ggaggattta aaatgcaaaa ggaatttata acagtaaaag aattgtacag
     8341 agaaaaagaa cagtacatag ggaagactgt aaaagtagct ggatggataa gaacatctag
     8401 agtatctaaa aattttggat ttatagagct aaatgatgga agcttcttta aaaatatgca
     8461 gatagtattt gatgagaaag tagaaaattt taaagaggta ggaaaattag caataagctc
     8521 atctatactt gtagagggag agttagtatc tacagaaggg gctaaacaac cagtcgaaat
     8581 acatgcaaaa agcatagttg tagaagggga atcagatagt tcatatccac tacaaaagaa
     8641 gagacatacg cttgaatatt taagaacgat agcacattta agaccaagaa gtaatacttt
     8701 ttcagctgta tttagagtaa gatcaatagc tgcctatgca atacacaaat tcttccaaga
     8761 aagaaacttt gtatatgcac attctccaat cataacaggt agtgactgtg aaggtgcagg
     8821 agagatgttt agaataacaa ctatggattt aaatgatatt ccaaaaactg aagatggcaa
     8881 aatagactat actcaagatt tctttggaaa agaggctaat ttaacagtta gtggtcaatt
     8941 aaatgccgag ataatggcac tttcttttag aaacgtttat acttttggac ctacatttag
     9001 agctgaaaac tcttatacag gaagacatgc ttcagaattt tggatgatag agccagaaat
     9061 agtttttgca gaccttgaag ataacatgga acttgcagaa gatatgataa aatatgttat
     9121 aagctatgta ttagaaaatg ctcctgaaga aatggaattt tttaatagtt ttatagataa
     9181 aggattgtta gaaaggttaa ataagatagt aaactctgag tttattagaa taacgtatac
     9241 taaagcagtg gaattattaa ttgaatctgg gcatgaattt gagtatcctg ttgagtgggg
     9301 atgtgacctt caaactgagc atgaaagata tataacggag caaatatata attgtccagt
     9361 gtttgttaca gattatccaa aagatataaa agctttctat atgagaatga atgaagatgg
     9421 taaaactgtt agagcaatgg atttactagt tcctggagtt ggagaaatcg taggaggttc
     9481 tcaaagagaa gaaagagaag atgtattgtt agatagaatt aatgaaatgg gattaagaga
     9541 agaagattat tggtggtatt tagaacttag aaagtttggt actgctactc actctggatt
     9601 tggtcttgga tttgaaagaa taattatgta tatgacaggt atgtctaaca taagagacgt
     9661 tatacctttc ccaagaactc ctaaaaatgc tgaattttaa taattatata taataaaact
     9721 tatataactt taagtataaa cactaaaatg acttgcatat ttatctattt tagagatatg
     9781 caagttattt ttattgtact ataaatatat aatttgatta cttttatttt gcgatataat
     9841 acttataggt ttatgtaata gtatgtaacc ttttaataaa atgcaacaca attacgtccc
     9901 tgttcttttg cagtatatag agccttatca caattactta taaactcatt taatgttatt
     9961 gtctttccaa ttttctttgt ataaactcca atactaacag ttacacattt taaaggaaca
    10021 tcatcacgct caaaattgca ggactctata atttttcgta aacattctga tttaagttta
    10081 gcatctgcct cattacagtt aaaaatacat ataaaaaatt cctcaccacc atatcgtata
    10141 gcatgttcat tttcagaact tgtaaaatct aaaattactt tggcaatatt ttgtagacaa
    10201 tagtctccct tttgatgtcc ataattatca ttaaattgtt taaaataatc tatatctatc
    10261 atcattccag ttataggttc ttgatttgca tggctgatta attttttttg tagaatatct
    10321 tcaaggtatc tacggttgtt cattttagta aggtcatctg tcataacttt gtcgttaagt
    10381 aaattattta tatgagatat ttcttcatat tgttgactaa ttaaaagttt atcatagtaa
    10441 gtaaatacac gatttctata tagcattgta gaaacaaaaa tggcaaggga tgttataaaa
    10501 aatgtgttga caatattact aaactcattg cctggtatag tttgaatccc aggtaagaat
    10561 aaattaagaa acaaaaagca tcctccaaaa actattactg attctccaaa ttttaatact
    10621 gagaaagctg cagctgctaa cataatataa ctaaatacac ttaggtcatt tccacctaac
    10681 tggtcaagta gagtaattac acaaccccat aggcagaaaa aagtcacata aattatccat
    10741 aaatttatat aaaacgtaca gcaatccttt tttttattcc aaaggtaaga aaatacaaac
    10801 ataaagacag aagatacaca aaatagtgtt acatacatat aaaaatacca ttggcgtctt
    10861 ggtgtgacaa aagggcctcc ttctctagct gagattgata tcatcataat tatttgagat
    10921 attactatta ttatgcaaat gattttaccc gtatgataaa gataattgca gagttctttc
    10981 tcaacattgt ctttgtgttt tttgtctaga ggaaatccaa aaaatttttt tattttttct
    11041 aagttcatat aagcctccat taaaaataaa gcataaaaat aagtattcct ttctatcatt
    11101 agatatttgg aatacttcgt ttatgattta attatatcaa aatatattgt gtgtaacaat
    11161 ctaaaattgt gatagataaa atttattaga taatgtcgag taactttatt gattaatact
    11221 ttattataat taagatttac agatagttta ctactgaaaa taaagaatag aataaattta
    11281 aattaagcat aataaaatat aaataataaa gttcgcatta acaaactatt taaatatcaa
    11341 gacctgttaa aaaacaacag caataaacaa ataaaataga taaatatatc caattaaggt
    11401 ataattaagt tttatatgat atagttatat ttgataattt acaatagtaa aacttggagg
    11461 gaaaaaatgg gtgaaaagaa aataaataat atgaattatt cacataataa ttattccaaa
    11521 aagacaggtg aaccaactag aaaaataaaa aatagccata tcactcttaa aagtaaagaa
    11581 gaaaaaattt gttctagttg caataaagaa aataatacta aggataatta ctgtaaattt
    11641 tgtggaaatg aactttatga aatagcatca ttaagaccac ttgaaacaaa actagacttg
    11701 aaatctaaaa taaaagagct ttcatatcat gcaaataaaa gaggtgtatt tttaacaaca
    11761 tttacaacca tatttatatt gtttattatt gcattgatat ttaaagctat tataactatt
    11821 caatttaatg atattagtta tttagtaaat ccagcacata taatcctagc tctcaacttg
    11881 ggtcaaatta gtgtatctat gtctaccatg atgggttctg ggtttataaa tgccaatata
    11941 ggtttgttga tattacttat aatccctatt ttggtattat taatatcaaa cctaattttt
    12001 atgagaaaaa gatgtagaga ttcaaaaact gtattagcaa attctctagg agttggaatt
    12061 ttttatggat tagttttagc tattttatct atttttacta atgtaaaaac tagttcacat
    12121 agtatgttag aatatggata tgcattagaa tatagttatg aattttttag tgttctttta
    12181 aatggattcg tattagggtt tatatgtaca tacataacta cttataaaaa aagttatgaa
    12241 aaagaaaata tgtatttatc tcttttttca aattctataa gaacattcat attaggttat
    12301 gttttagtat tagtaatact attggtacta actatatctg atagtagtta cttaaatgaa
    12361 ctagatatga gtagttattc aaatggatta aatttattta ctatactccc acaaatagct
    12421 agttatatgt gggcttttgc aaatggaatt tcagtaacca taataaactc aacagtatca
    12481 atgtttactt taagttcttc atctttattt ggagatacta aattaatgtt ttatgcaatg
    12541 ggagcattgt ctatgttaat attattatta aatggataca agctaagatt taagtataat
    12601 acagatagta taagacctat aatagtattt agtatatatt atgcattttt gatgggaata
    12661 ttggccttat ttagtacatt tatactagat agtaatatta atttctttaa tacaactaat
    12721 tatggaacaa ctttaataat gcaatttaaa gtcttacaag ctattgtaat ttcatttgta
    12781 tatagttttg tgatatcttt aataggatat aagctaaatt cagctgatta aatatgattg
    12841 gagggaattt ctgtggaagg aaatactaat aataaagtag atgataaatt ttctaaggtt
    12901 aagaaaaagt ttggtagtgg aaaatttaaa gttgaattat ataaagaaaa atcaaaatta
    12961 aatagagaga ttgatgatat tcaagaaaag aaagcaaaga tattcttgga aatgggaata
    13021 ctgacatatc aaaaaattag agaagattct attaatgata atagttttga taaattctgt
    13081 gatgagttac tagaacttga taagttaatt tatgaaaaaa atatggaaat taatgaaatg
    13141 gaaatggcag aaagtaatgt aacttgtgag tgtggttatg ttggaaatgt aaatgataaa
    13201 tattgtgctg aatgtggtaa aaaatttgaa ttggaaaatg aatgtgatga ttttataatt
    13261 tgtggttatt gtgaaagtga gatagataca gaggctgaat tttgtccatg ctgtggaaga
    13321 aaaattataa tggatttaga ataatattgg gaaacctatg tatagtatac atgggttttt
    13381 ttattgaaat tatttaaatg gacttataac agtagttata taaaatgaaa ataaacacca
    13441 aaaaaatgaa ataaaatttc ttttaaatgt aaaaaacaag ctaatatata aaataaatca
    13501 gtaaaaatat agatgcgaga aaaaatatga aaaaatattg caaagaaaaa gttttcatgt
    13561 tattattaat acataaatca agaaaataaa tttcagaaac gaggtaattt aaaaaatgct
    13621 agataaggta aagggaagat taatagtatc atgccaagct ttagaaaatg aacctcttca
    13681 tagtcctttt ataatgggga gaatggctaa ggctgctatg gaaggtggag ctgttggaat
    13741 tagagctcaa ggagttgaag atattattga aataaaaaaa gttactggac ttcctgttat
    13801 aggtattata aagagaaact atgaagattc agatatatat ataacgccaa ctaaaaaaga
    13861 agttgatgaa cttttaacaa cagggtgtga aatgatagca ttagatgcta ccaatagagt
    13921 tagaccaaat aatgaagact taaaagaact tataaagtat ataaaagaaa acggtgttct
    13981 agtaatggca gatatttcaa attatgatga ggctatcaaa gcacaagagt acggtgtaga
    14041 ttgcgtttca actacactat ctggatatac tccatatact aaaacattag aaggtccaga
    14101 ttttgtatta atgaaaagat tagttaaaga tttagaaata cctgtaatag ctgaaggaaa
    14161 ggtaaatact cctcaagatt taaaaaaggt ctttgagttg ggtgttcatt catcagtagt
    14221 aggttcagca ataacaagac cacaattaat aacagaaaaa tttgttaaag caattgaaat
    14281 taattaaaaa ttaatttata aattaaaaaa ttattatatt taactatatt tgaaaattaa
    14341 aattggaggt aaagatatga gaacaacaga tatgaaggga atttattcag cattattagt
    14401 ttcatttgat aaggaaggaa atataaatga aaaagggtta agacaaataa ttagacacaa
    14461 tatagatgtt tgtaaagtag atggtcttta tgtaggagga agtacagggg aaaacttcat
    14521 gctttcaact gatgaaaaga aaagaatatt tgaaatagct aaagatgaag tgaaagaaga
    14581 aataaaatta atagctcaag ttggttcagt taatttaaaa gaagctgtag aacttgctaa
    14641 atttacaact gatttaggat atgatgcaat aagtgctgtt acaccttttt actataaatt
    14701 tgattttgaa gaaataaaac actattataa tacaataata aattctgtag ataatagatt
    14761 aataatatac tctataccat ttttaactgg tgttgatatg agtttagacc agtttggaga
    14821 attatttgaa aatgaaaaaa taataggtgt taagtttaca gcagcagatt tctacttatt
    14881 agagagaatg agaaaaacat tcccaaataa attaatattt gcaggatttg atgaaatgat
    14941 gttaccagct acagttttag gtgtagatgg ggcaattggt tctacattca atgtaaacgg
    15001 tgtcagagct agacaaatat tcgaattaac taagaatgaa aaaatatcag aagcacttga
    15061 agtacaacat gtgactaatg atttaataac agatatatta ggaaatggct tatatcaaac
    15121 aattaaatta ctacttgaag aacaaggtgt tgaggctgga tactgtagac aacctatgaa
    15181 agaagcaact gatgaaatga aatcaagagc aaaagaaata tacagaaagt atttttaata
    15241 aaatactttt agtatgggag gattagtcaa atggtaggat ttacttggat agattttgca
    15301 atactagtgg tttacttatt ggcagtttta tttgcaggat tgttattttc aaaaaaggaa
    15361 atgaagggaa aagagttctt caaaggtgat ggaactattc cgtggtgggt tacatcagta
    15421 tcaatatttg ccacattatt aagtccaata tcatttttat cattagcagg aaattcttat
    15481 ggtggtactt ggattttgtg gtttgcacaa ttaggtatgt ttatagcaat acctttgaca
    15541 ataaaatttt tcttacctct atatagtagg ttagaaatag atacagcata tgaatactta
    15601 gaaatgagat acgaaagtaa aggtcttaga gtacttggag ctttgatgtt tataatatat
    15661 caaataggac gtatgtctat tataatgtat cttccatcaa tagttctggc tggtcttaca
    15721 ggaatacctg taaatgtact gataatagtt atgggtgtaa tagcaataat ttactcatat
    15781 acaggtggat taaaggctgt cttgtggacc gattttatac aaggaatggt attaatagta
    15841 ggtgttacag ggacattgtt ctatttaata gcaagtataa atggtggttt tggaacagta
    15901 atggatactc ttacaactgg acacaagttc ttagcaagta atgaagttat gtttgataaa
    15961 aatatactat ctacaagtgc atttataata tttgttggag ctggtcttaa tactttttca
    16021 tcatatgtat cgagtcaaga tatagttcaa aggtttacta caacaactga tataaagcaa
    16081 cttaataaaa tgacatatgg aaatggtgtt ttatcaatgg gacttgcaac agtattttat
    16141 ctaattggaa cttgtttatt tatatactat actcaaaacc cagatttagc tcaaacagtt
    16201 caacaagacc aagtatttgc atcatatata gcttatgaat taccagtggg tataacagga
    16261 atactacttg cagcgatata tgcagcttct caatcaactt tatcgacagg gcttaattca
    16321 gttgctacaa gttggacttt agatatacaa actatcataa caaaagatat aagtatggaa
    16381 aagcaaacta agatagcaca atatatatca ttaggtgtag gtatactttc tatagctgtt
    16441 gcaatagtat tagcaaatgg agaaataaag tcagcatatg aatggttcaa tagttttatg
    16501 gggctagtac taggtgtttt agcaggaata tttgtacttg gtgcattttg taaaaaagca
    16561 actaaaatgg gagcatatgt tggattcata gtatcagcaa ttttagttgt ttatttaaaa
    16621 taccgtatgc cagaagtaac ttcttgggca tattctctaa taacaatcac gacttctgta
    16681 gtggtaggta caatagttag tgcaatagaa gctaaagtta aagcaaaagt atctttacca
    16741 aaagctgaga ctactgttta ttatgaaaaa taatatttaa atgataaatt gtcttataga
    16801 gtgattagat aaataattta gttactctat aagattgtat aatatacttt gtatacaaaa
    16861 gtataaaaat agactttata attatatagg gagatagtgc ttatgatatt tggaaatata
    16921 aatcatagta agacatattc aacattgcat gaagatttac ttagatgttt tgaatatgct
    16981 aaagataatt cattaataga ttatgaaaaa ggtacttata caatagatgg tgatgatatt
    17041 tttgtgaata ttgtagagta taaaacttgt gaaaaagaag atagattctg ggaagctcat
    17101 aagaagtata tagatgttca tttgatgctt gatggatgtg aacgaataga tataaatttt
    17161 atagaaaatt tagaacaaaa aatatatgaa gaaaagggcg atttcttgcc tcttgatggt
    17221 aaaaataatg gatacatgga acttagaaaa ggtgattttt tagtttgtta tccggaagat
    17281 gctcatatga caggaataaa agttttagaa aaagaaaata tcaaaaaagc tatttttaag
    17341 gttttggtta gataatgata atttatataa ccactagggc tgaaaatagt gatttaactt
    17401 tcagcgatta gtgagacttc gtaaatttta gttagattac tattttcagc cttagttttt
    17461 tatgagaaaa ttaaaaataa ttaaaagctt aaaattttgt aaaggagtta acttatggaa
    17521 aatatagatg tattcttatt aataggacaa agcaatgcta gaggattggg aaatccaaaa
    17581 gagagcatca ttccaaatga aaattgtttt gaatatttga gtactgatga aattataaat
    17641 atgagatgtg agctagagac ttcagaaggt gatggtacta tagcacctgc attttcaaat
    17701 gaatggaata agcttactgg aaataaagtt tgttttattc acaatgcaaa agatggttca
    17761 agaataaaaa actggaatca tgataataac tggtttctaa atgacactat agaaaaattt
    17821 aatacaggct gtactacctt aagtaaacat tataatatag aaaataaata cgttatttgg
    17881 attcaaggtg aaagtgatgc aaaatatggt agtgatgtat tgtactataa agaaagtcta
    17941 aaaaaaattg cgtataggct taaagaagaa tgtatgattg ataaaatgtt tgtaagttta
    18001 actggttatt ggcttggaga agatgaatat tttattagaa caagacgaat tgcagcagca
    18061 caggagtcgg cttgtagtga atgtgatata ttatgtgtag gaagcaaaat tgctatgcag
    18121 tttcatgaca gaggattaac tattgatgat gttcattaca ctcaagaagg tcttaatatg
    18181 ttaggagagg acttatgtaa aaatatttat aagtatcata taaccaaaga aaaaagtgta
    18241 ttaagtgata ctatagactt atcagaagca aggaaatata tctgtgaatt ggaaaagata
    18301 agtaaaagat ttgtgtaata taaaatttta aatagagttg ttaatttata aaaataattt
    18361 gtatggagat atgttatgaa aaattacgtt tgtatagatg ttggaggtac ttcaataaaa
    18421 tatggtttta ttagagaaga tggatttata attgataaat caagtcttga tactgaagca
    18481 aaggaaaaag gtggagaagg aatattagcc aaaataaaag atatagtaaa aaaatatata
    18541 gaggaaaatg aaataagtgg tatatgtata tcaactgcag gtatggttga cccagttgaa
    18601 ggtaaaatac tatttgcatt agaagaatta attccaaact ataaggacat gcaattaaaa
    18661 aaagaagtag aaaaagagtt taatataaaa tgtgaagttg aaaatgatgt taattgtgct
    18721 ggacttggtg aaatgtggct tggagcaggt agaggtgcaa catcttctat atgtttaaca
    18781 ataggtactg gaattggtgg atgtattata ataaataata aactgataaa tgggtttagt
    18841 aatagtgctg gtgaagtagg atatatgaat gtaaatggaa gttcttttca agaattggca
    18901 tctactagca gtctaattaa aaaagtagca aaaataaaaa atttgaatga aaatgactta
    18961 aatggaaaaa taatttttga tttagcaaag aataatgatg aagattgttt aaaagaactc
    19021 gataatatga taaaatcatt agcagttgga atcgcaaata tatgttatgt aataaatcca
    19081 gaagtggtaa ttttaggtgg tgggattatg gcacaagaaa agttcctaaa accaaaaata
    19141 gacaaagcat taaaggaggt tcttatagag agagtttaca aaaacactaa tatagaattt
    19201 gcaaagagac aaaatgatgc aggaatgctt ggagcattat ataatttttt aaacaaaata
    19261 taaagaatag aagggttttt aatgagtatt ttagaacaat tggaatcacc aacttttaaa
    19321 gtcacaaaat cagataaatt attaatagct tatataaaag aaaatataga tgatgtattt
    19381 tataaaccaa tatcacaaat agctaaagag agcaatattg gtgaagcaac tataactagg
    19441 tttgtaaaaa aaatgaattt taatggatta caggatttta aagttacttt agcacaagaa
    19501 atatcaacta tcaataaaaa aaatattata aataaaaata tacaaaatga tgagccagct
    19561 ttggatacag caaaaaaact tttaagttca aatgtaacca ctttagagaa cacagtagag
    19621 ataatcaata gtaaggatgt acatgactgc gcaaggctta taataaatgc aaagaaagtt
    19681 tacttcatag gtattggata ttctggtata atagcacagg attcaaacta taaatttatg
    19741 agaataggtc ttaattgtgt aagttttgac agtagtcata caatgataat gatgtcttcc
    19801 ataatggaag aaggagattt aataattgca atttcacatt ctggtgaaac agaggagatt
    19861 ataaaaactg taaagcttgc aagagccaat aatgctaaaa ttatatcaat tactgaaaat
    19921 aaaaattctg aattaaagga tatttcagat gtacacttat cttatgtatc gggagaaaca
    19981 gtactggaaa ccggttcaat atcttctaaa ttagcacaat ttttcattat tgatttagta
    20041 tatacacagg tagtaaaaga actttctaat gaagctattg aaaggaaaat taaaactaca
    20101 aatgctataa aattgtttaa aaatgaataa aataagaaat ttgtaatgtt ttatagagct
    20161 ctcttaaaaa tttaggaatg gagagatatt acatgtctaa attaaaagat tataatattg
    20221 ataaagtaat aatttttaat aatttaagta ctaaaacgaa gaatcaactt aaagaaaaag
    20281 ttaaactaaa aagattacaa aaaaaagaaa ttttatttta tgaaaaagat agcttagaca
    20341 gtgtttatat acttttagaa ggaaaggtat ctatttttaa gataagtgaa aatggagaga
    20401 gaaaagtaat tttcatatta aatagtgggg aagtcataaa tgatattaca cttgacgctt
    20461 ctaaaaactc tactgttggc tgtgaagcat ttgaaaattc aattgtagct tattatagta
    20521 ttgaagaatt tttagaaatt atgcaaaatg attttcaact tacaaaggat attatttctt
    20581 atatggaaag aagaataaga cgtttatata gacagttgaa aaattctata tctataaaag
    20641 tagataaaaa acttgcagca aaattatata ggttaagtag agaatttgga gtttgctgtg
    20701 gagaatggac tttactaaat gtaaatatta cagttacata tttagctgat atgcttggct
    20761 gtaaaaggga gactgtttcc agaatgataa aggtattgca aaaagaagaa cttattaaaa
    20821 ttgacaataa aggtttttat gttaaagaaa ctgaattatc aaggtatttt aaaaataatt
    20881 aattatgatt aagtaagagt attattagaa ttttaattaa ataaaaatat tattaagaga
    20941 atctatttat agattctttt ttattgtcta atttattaat ttttatttta ccctattgaa
    21001 ttgtataaaa aaacaaataa gattcttttt tattcaaaaa acttactaaa tttttgatta
    21061 tcttttcata agttggtaaa tgccgatata tcccgtattt gagggcttta tcggtatttt
    21121 ctttttggaa gataccttgc ataagctggc atttaccagc atgaaaatgc aaccaaaagt
    21181 agtaaatgag tagtaaatat acgttccgat attaacaagc cagtctttcc agttctgctt
    21241 ttgcagattg gaatgtaccg tgtgcgtagt agccaagcgt catggttatg ttagcgtgtc
    21301 ccatgagata ttgcagggtg ttcgggttca ttcccttgtt tgccatattc gtacaatagg
    21361 tatgtcggaa tgaatgtggt gtaatgtttg gtaacttgtc tttgtggtat ttgttatact
    21421 tcttaatcag tcctcgtacc atacccacat agtttccagc gactttaggc aatccctcac
    21481 ggtttaagaa taggaaattg ctgtaaccac caacaaccag cggttgagct tttactctgt
    21541 tctttagtat tctttggagt gcttgataag ccctttccgt caatggaatt tttcgttttc
    21601 cgttctttgt ttttggagtg tcaatatagt agccgatttc gctatctctt aatagctggt
    21661 ggtctatatt gagtattctg ttctgcatat caatatgcgt tgtcagtccg caaaattcag
    21721 aaatacgaag tcccgtttcc agaagaagca caacctcatc ataatacttg ctgtaaatct
    21781 tatccgtttc cataaaggca agcaggcgtt cttcctgctc tggcgtaaga ataactttcg
    21841 gctcggtatc atcttccaga acatcactta gcttaaattc aaacgggttc tttctgatac
    21901 agtcgtcttg tatcgccata taaaatgacg ctttcaagga acgcttatag ttgtcaatcg
    21961 ttttgtaggc atatcctctt tcactcattc tgatagccca ctctttagcg tccgactgtt
    22021 tgacggtatc aatcgctctc atacccaatg ggtcattttt cagagcgttc ataagatact
    22081 gtcgtccttt ttccgtagct cgcttgatgt tctttctttg gctgttcttc ttgtcgtaaa
    22141 gctggcagac tgtcatttta ccgcctgccg tgtcaatacc gtcatcaagg tcttttttta
    22201 tctgtgcttc tttttccctc aacgatatat catcacgttt tccagcaggc gttttgtctg
    22261 tcggtacaag tttccaagca taaataaact gtggctttcc gtatatatcg gtatatttat
    22321 aaacgtatct tccgtctttt cgctggctct ctccattacg caaattgcga tttttactgt
    22381 cttttcgttt cacattagac atagtgtaaa gctcctttcc gtcatggaat gagccgtgat
    22441 acgctatact tattatacca tatccacggc tctatgacat tagatttcgt ccaatgtatc
    22501 tatgattttt tcaaattgtt ttcgctttat ctgaatacgg ttgccgttca cgataaccca
    22561 gccagcgtca atattttctt cggctaattt acgcaacttc ttttctccaa tgcggaagta
    22621 tttggacgct tcttcaatcg tcagtgtata tttttcccag ataggcacat cagtattatt
    22681 cataatttat gcaccccctt tactgtgtgt cagtctataa gttatataaa caggcagacg
    22741 gctttggaaa gctccattag tatttcaact attcccattc ttgtgggcag aaccgcacca
    22801 tgcggaagta tcattatgct gtaagggtag gtcatggcaa aacgactttt ccaacggtcg
    22861 ctctcggatc actgcgtggg tcgctcgctt tcttttggaa aggtcatggc gtacagttcc
    22921 cgtggctctc tatccttaca aacgtatctg tctgctttat tcagttttca aagagctgtg
    22981 gcgaaagcgg tatgctttca tgtaaaagca ggagcagagc aggaaagagg ggattgaaca
    23041 aatcatgctc tgcgttactg ctggttattc ttcttcaatt tctaaggcaa tatcaaaccc
    23101 taaaatcatt ttgataagtg cttctcggat aagtcctttt aactccatat ctacaacgat
    23161 ataaacatta ccgtattcat catagagtgg acgcaaacag cacttcgata tgtaagggtc
    23221 ataaaatgca agtacctttt caatcgcttt ttcgtccccg tccatagctt gtgaaagcaa
    23281 gtagtaagac ggcttcttaa atgtgtgttt catttgctat cgtttctcct ttaatagttt
    23341 tctcataagt gccaatgaat tgtggcggtt ctgaaaaact ccgcttctgg aaatgttttg
    23401 ctttttggcg atttcttcat tgttcatttc caaaaagtaa tacatcaaca aagtttctcg
    23461 gttacgttcg gataactgtt tcaaggcttc tgccaattca tcatcataga cacgaatatc
    23521 attaccgcat acattgaaaa tcgtatagtc tgtttcgtag tcgtcccata cagccaagtt
    23581 ttcaaccatg atttctggaa gttcacaaaa ggaaatttct ttttcttttc ttcgcttcaa
    23641 tccctgctga tagtccttga caacatgacg gacaactttc ttcaaacagc tttcaaaacg
    23701 gcattgaaca gttttctgga agtcagacgg tttcatcaat ctcaccccct ttccgttatg
    23761 acgtgaaaag tgtttatccc tctttccgca ccatataggg aatggcaagt gtgatttgtt
    23821 aagttgaaac cagaaaaaat cgaaaaaact ttttagtaaa acaaaaacag cccgtgtgaa
    23881 tgtgaataca caaacggact gctttataaa tgctatctgt atgaattttt aactcttgta
    23941 gagggtagaa tgattgtaat actgaactaa aatatttttt cagttgggaa cagcaaagta
    24001 ttattccata tacaatcatg gcgtagcccc ctttaccaga gctatacctt gtgccaccaa
    24061 tgaaaaagga cggctctggc tatatccaaa accgccccgt tatgttttca agacgcacaa
    24121 aagtatatca tctcggaacg gttatggtga tttaaaatga gaaaaacaaa agaaacacat
    24181 acttttgatt tcagaccgct agggctggca atcagagaag cccgtgaaaa agctgggctt
    24241 tctcgtaatg atttaggcga taaggtattc tatggggaa
//
LOCUS       DAMJVG010000059        22846 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.059, whole genome shotgun sequence.
ACCESSION   DAMJVG010000059 DAMJVG010000000
VERSION     DAMJVG010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22846)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22846)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22846
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.059"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            <1..249
                     /locus_tag="PC512_002555"
     CDS             <1..249
                     /locus_tag="PC512_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HDF2442290.1"
                     /translation="EEDEFVQAAYKGLKEAGIDSEITQYSFCTNGSHYAGEAGIRTIG
                     FGPSKENLAHTIDEYIELDQLFKGAEGYYGILKSVYKK"
     gene            265..1848
                     /locus_tag="PC512_002556"
     CDS             265..1848
                     /locus_tag="PC512_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacylase"
                     /protein_id="HDF2442291.1"
                     /translation="MRTLIKHGLIVDGNKTPAYEGDILIENEKILKISQDLNEEADKV
                     IDAKGRVICPGFIDTHSHSDLVILVNPYNEVKIRQGITTEVLGQDGISMAPLPQEHIS
                     SWRKNLAGLDGESDEIDWKYETTENYLKMMDYNGVGLNETYLVPHGNVRMEAMGLEDR
                     PATKEEIQKMCEITERELKAGAIGLSTGLIYIPCAYSLTEEIIEMCKVVAKYDGVFVV
                     HQRSEADTILTSMEEIIEIGKQSGVKVHFSHFKVCGKANWKYIPQVIELLEKAEKEGI
                     RVSFDQYPYAAGSTMLGVVLPPWAHSGGTDKLIERLSDENERAKMKKDIANGIEGWDN
                     FIEFAGIDQIFVTSVKTEKNKDTIGKSLLEIGKMRGKDPLDATFDLLKEEENAVGMVD
                     FYGLEEHIIGFMKRDEQNVCTDGLLAGKPHPRAYGSFPKILGRYVRELNVLTIEEAVY
                     KMTKKAATSFSIKDRGELKEGYFADIVIFDKDTVSGCDDFINSMQYPTGIDYVIINGN
                     CVVEEGKYNKIKAGKVLKN"
     gene            1876..3204
                     /gene="ssnA"
                     /locus_tag="PC512_002557"
     CDS             1876..3204
                     /gene="ssnA"
                     /locus_tag="PC512_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative aminohydrolase SsnA"
                     /protein_id="HDF2442292.1"
                     /translation="MILVGNGRLISQDSLNPYMEDGCVVINDNLIEDIGTTEEMKAKY
                     PVHEFIDAGKKIIMPGLINSHMHIYSSFARGMAVPGKPSENFLEILNNLWWRLDKQLT
                     LEDTKYSAYATYIECIKNGVTTVYDHHASPNAIEGSLFTISDVAKDLGIRTCLCYEVS
                     DRDGGNTIQQGINENVNFIKYAQKDDTDMIKGMFGLHAAFTLSDDTLNKCASEMAGLD
                     TGYHVHVAEGLADLQYNVDKYGKRVLERFNDFGVLKEKTIAVHCIYISAEEISLLNKT
                     NTFVVHNPESNMGNAVGCSPAIELLKRGVTVGLGTDGYTSDMFESLKVANIIHKHHLK
                     DPRVGFEESQTMLFDNNRKIAKAYYKNDLGVLKKGAYADVIVVDYIPHTPLTENTIGG
                     HTIFGMSGRSVDTTIINGKVLMKDRKLINIDEESILAKSRELSQNLWNRI"
     gene            3349..4701
                     /locus_tag="PC512_002558"
     CDS             3349..4701
                     /locus_tag="PC512_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HDF2442293.1"
                     /translation="MSRDKSPKIAPVDERLPVSKSWVFSLQHVLAMCAGAVAVPMMIG
                     SAARLDHASIVFLINACLFMAGIGTLIQSVGIGNIVGAKIPVIEGTSFAAVAGMTAIA
                     SSYSDSQVAIQTVFGSVIVAGLFCILLAPVFEKLIRFFPSVVTGTVVMVIGISLFPVG
                     IKWITDNKLEAVEPNSLALALAVLAITLLSFKFLKGIWNSTAILVGIVLGTLLSMAVG
                     MADFSAVNGVGWLNLNVPLKFGMPRFEPSAILSLCLIMLVLMTESVGNMIAIHEMVDK
                     EVTGKNIKRGLFGDGISTALSGIFNSFPITPFGQNTGIVGLTGIKSRFIAVYAGVILL
                     VLGFLPKFAAIIGAIPKPVLGGVGFAMFGMVMVGGVKTLSKVKFDGTKNGVIVAVSVG
                     LSMIPLTNPDFYHNFPTWVQTIFHSGITTGSLSAVLLNIFFNELGSKKEKNNKVEEAK
                     "
     gene            4893..6002
                     /locus_tag="PC512_002559"
     CDS             4893..6002
                     /locus_tag="PC512_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF2442294.1"
                     /translation="MANLKVNLYGMEFLNPIMTAAGPGAKDGALCQEAAKGGAGAICT
                     KTISVLPADVPRPCMAKTNSGFLNTELWSELPKEQWIEEEYKKVKETGLPVIVSMGYS
                     AEQIAEVAPLVKPYADAVELSTHYVGTDVAPIVNALKAAKAVLDVPVFMKMSPHTDIQ
                     TIAKAVEEAGADGLVMINSFGPCMAIDVNTGYPIMGSKAGYGWLSGAPIRPLAIRCIY
                     EASQVVNIPIIGVGGITCGKDVAEMMMAGASAVQVCTEAILKGPSIYGKIAKELNEFL
                     DENGYADVNEIKGLTHKKMAARGFRTHSVAPVVDDNKCIKCKQCVTSCVYEALEVTDK
                     LNIDADKCFGCGLCVTRCPKGALSICYNQVEAMNE"
     gene            6285..7676
                     /gene="hydA"
                     /locus_tag="PC512_002560"
     CDS             6285..7676
                     /gene="hydA"
                     /locus_tag="PC512_002560"
                     /EC_number="3.5.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropyrimidinase"
                     /protein_id="HDF2442295.1"
                     /translation="MGIVLKGGKVVTSEKTYCADVRIEDEKIVDIGLDISKENDEIVD
                     VSDSYVIPGGIDTHTHFDLDTGVTKTADNFETGTKAAIVGGTTTILDFATQAKGCSLK
                     DGLEEWHEKAKDKSYSDYGFHMAITDWNDSVCNEMEDMVKEGVSSFKLYMAYKGSLQV
                     DDGVIFEALRKAEEIGGIIGFHCENGDIICELVDKAKSENNLSPKYHQLTRPAIMEAE
                     ATSRLMKIAEVANSKVYVVHLSCKESLEEVLKAKQRGVDVIVETCPQYLLLNDELYDL
                     DGFESAKYVMSPPLRNKENNEILWNAILDNQIDTIGTDHCSFNYKGQKELGINDFSKI
                     PNGSPGVEHRMSLLYTYGVCKNKISINKMVEVTSTNAAKLFGMYPNKGTIEIGSDADI
                     LVLNPNKKSKIEAKKQLQNVDYTPYEGYEVDCQIEHVYLRGKEVVRDGELICNTPSGR
                     YINRRLTKGAREW"
     gene            7670..10231
                     /gene="xdh"
                     /locus_tag="PC512_002561"
     CDS             7670..10231
                     /gene="xdh"
                     /locus_tag="PC512_002561"
                     /EC_number="1.17.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenium-dependent xanthine dehydrogenase"
                     /protein_id="HDF2442296.1"
                     /translation="MVEFILNGEKVVAKEGKKLLDFLREDMNITSVKNGCSEGACGTC
                     MVIIDGKATKACVFKTDKLAGKNITTIEGLSERERDVFAYSFASQGAVQCGFCIPGMV
                     ISSKALIDVNNNPTEDDIKKALKGNICRCTGYVKIIKAVDLAAKIFRENIDVPKVNCK
                     GLVGENLPRVDAVGKALGYSEYVDDMRIEGMIYGSAVRAKYPRALVKKIDIEEAKAYP
                     GVVAVLTAKDIPGTIKVGHLKKDWDTLIPEGEITRYLGDGIVLVAAETREALEEAKKL
                     VKIDYEELTPLSTTEDALREDAPKIHETGNILVKEHLVRGNAKEKIENSKYVVTKRYT
                     TPATEHAFLEPECAVAGPYEEDGVIIYSTDQGVFATQHECADMLGLPYEKVRVINKMV
                     GGGFGGKEDMSVQHHAALLAYHTKRFVKVQLTRKESIIVHPKRHATEMEFTTACDENG
                     YLTGMKATIISDTGAYASLGGPVLQRLCTHAAGPYNYQDIDITGTAVYTNNPPGGAFR
                     GFGVTQSCFATECNLNLLAEMVGISPWEIRYKNAIRPGQVLPNGQFADEGTAMAETLE
                     AVKEEYEKHPRAGIACAMKNSGVGVGIPDVGRCRLVIKDGKVHIRTSASCIGQGLGTV
                     MTQVVCETASLLPENVVHEVPDTHLTPDSGNTTASRQTVFTGEATKVASNKLKEALDS
                     GKTLLDLEGEEFYGEYESITDKMGCDKENPVSHVAYGYATQVVILDENGKLEKVVAAH
                     DVGRAINPISLEGQIEGGVVMGLGYALTEDYPVVNSVPTAKFGTLGLFKSTDIPEIQA
                     LIVEKNKDLLAYGAKGVGEICTVPTAPAVQNAYYVFDKEFRTELPLQNTPYSKKK"
     gene            10455..11801
                     /gene="rpoN"
                     /locus_tag="PC512_002562"
     CDS             10455..11801
                     /gene="rpoN"
                     /locus_tag="PC512_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HDF2442297.1"
                     /translation="MNFNNSLELTQSQKLIMTTQLKQSLSILNMSKLELEEEIKREAE
                     NNPLVEVEKSGEINWEEYIKDMDRSRRLDRTEISYNPDNEVNLENLVKYSSNLYEDLK
                     FQISLYKLTDKELEVCEYIIDSLDEDGYLRTEEKVIVDTLKIDEELFEKCLISVQQLE
                     PSGVGARSLSECLMIQMASLGIYNEILEEIVTKDLNLIANNKYKEISKKYNMSLQKCV
                     ELINIIKTLDPKPGRTCSVEKSVYIQPDVTVEKIDDEFIVYLNEKDSYQIRINSYYKD
                     ILKNSQSDESAKEFIKERLNSATGLMKNIESRKTTVLKIAEEIVKAQDEFLRKGTKYI
                     KPLKMKDIAEKLEFHESTISRGVNGKYMLTPFGVYEFRYFFSSAIETENNEMASSTSI
                     KKIIKETIKDENKKKPLSDDHISKLLKEKGINVARRTVAKYREELGIPSSSKRKEY"
     gene            12597..13619
                     /locus_tag="PC512_002563"
     CDS             12597..13619
                     /locus_tag="PC512_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDF2442298.1"
                     /translation="MKNLLEIQKKLIPQAIELMERRYSILRQISLSEPIGRRTLSNVL
                     EISERIIRSETEFLKEQGLIDVAVSGMTITKEGSDLLDKLKDIMSDIMGLSKLQDRVR
                     EKLGIKRVILVPGSCDENGSLLKDVTRYGCEYFLGILKDGDIVSITGGSTMLEFSNVI
                     KTDKRYPNSTIVPARGSMGTDVEMQSNNIVASISKKLHSNCKLLHIPDELDESAMKTL
                     SQVPEIKTTLEYIKRTDILVFSIGRADVMAKRRKLPEDKVDEILSKNAVGEAFGYYFN
                     KDGEIVYKLNTVGIDLETVKQVKETIAIFAGTEKVEALLAISNMHKNMVLVTDEESAY
                     KILSLL"
     gene            13679..14686
                     /gene="gap"
                     /locus_tag="PC512_002564"
     CDS             13679..14686
                     /gene="gap"
                     /locus_tag="PC512_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HDF2442299.1"
                     /translation="MVKVAINGFGRIGRLALRKMMEQQDKFEVVAINDLTDAKMLAHL
                     FKYDTAQGRFNGEIEVKEGAFVVNGKEIKVTAERNPADLPWAELGVDIVLECTGFFTS
                     KDKAEAHIQAGAKKVVISAPATGDLKTIVFNTNSDILDGSETVISGASCTTNCLAPMA
                     KVLNDKYGIEKGLMTTIHAYTNDQNTLDGPHPKGDLRRARAAAGNIVPNTTGAAKAIG
                     LVIPSLKGKLDGAAQRVPVVTGSITELVCTLGKNVTVEEINAAMKEASNESFGYTEEM
                     LVSSDIIGISYGSLFDATQTKVMEVDGKQLVKVVSWYDNEMSYTSQLIRTLGYFAQLA
                     K"
     gene            14908..16110
                     /locus_tag="PC512_002565"
     CDS             14908..16110
                     /locus_tag="PC512_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HDF2442300.1"
                     /translation="MSMLNKKTIEDIDVCGKKVLVRCDFNVPLQDGVITDENRLNGAL
                     PTIQYLISKGAKVILCSHLGKPKGEAKPELSLAPVAKRLSEMLGKEVVFAADDNVVGE
                     NAKKATEKMENGDVVLLENTRYRKEETKNEENFSKELASLAEIFVNDAFGTAHRAHCS
                     TVGAGEFLQERVCGYLIQKELKFLGEAVANPVRPFTAILGGAKVSDKLAVINELLEKV
                     DNLIIGGGMAYTFLKAQGYEVGTSLLEIDKVEYAKEMMEKAKNKGVNLLLPVDVVMAD
                     HFAPDATPIVTEDANVKEDYMGLDMGPKTIANFVKTIKESKTVVWNGPMGVFEFENFA
                     NGTLSVARAMAELTDATTVIGGGDSAAAVNQLGFGDKMTHVSTGGGASLEFLEGKELP
                     GIAALDNK"
     gene            16136..16879
                     /locus_tag="PC512_002566"
     CDS             16136..16879
                     /locus_tag="PC512_002566"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HDF2442301.1"
                     /translation="MRKPIIAGNWKMHKTIKEALEFVNEVKDKVNSDKVEAVICAPFT
                     LLKDLKEATKGTNIKIGAQNMHFEEKGAFTGEVSPLMLKEIDMDYVVIGHSERRQYFN
                     ETDETVNKKVLKALEVGIDPILCVGETLEQREAGKTKDVCKVQVEKALENVLKDDLAK
                     VVVAYEPIWAIGTGKTATAEDANDVISYIREVIKGLYGELANEVRIQYGGSVKPSNVA
                     EIMGQSDIDGALVGGASLASNDYLDLVNF"
     gene            16888..18420
                     /locus_tag="PC512_002567"
     CDS             16888..18420
                     /locus_tag="PC512_002567"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003228330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-independent
                     phosphoglycerate mutase"
                     /protein_id="HDF2442302.1"
                     /translation="MMKKPVALIIMDGFGYNKDVKGNAIAESKTPNLDRIKKEYPNTL
                     INASGLDVGLPDGQMGNSEVGHTNIGAGRIVYQDLTRITKSIKDGDFFTNKVLCEAMD
                     NAKENSLHVMGLLSDGGVHSHIDHLKAIIKMAKDKGVQKVYVHAFTDGRDTDPQSALE
                     YAKEVQASMDEIGVGEFATVSGRYYAMDRDKRWERVELAYNAMVRGIGEKANSIEEAI
                     QNSYDDGKNDEFIMPTVIMKDDKPVGSIKENDSIIFFNFRPDRARQITRALVCEEFDG
                     FKREDIKNFFVCLTEYDITIENVHIAFGPQSLANTLGEYLAKNGKTQLRAAETEKYAH
                     VTFFFNGGVEEPNKGEERLLIPSPKVATYDLKPEMSAYELTDKALDKLGEDKFDFIVL
                     NFANPDMVGHTGSIEAAIKAVETVDTCVGRLIDKIVELGGSAIITADHGNAEYMLDPE
                     TGKTVTAHSINPVPFIVVGQEYESAKLLDGGRLSDIAPTVLDMMKLEKPEEMTGHSLI
                     SK"
     gene            19008..20300
                     /gene="eno"
                     /locus_tag="PC512_002568"
     CDS             19008..20300
                     /gene="eno"
                     /locus_tag="PC512_002568"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HDF2442303.1"
                     /translation="MSVIELVYAREVLDSRGNPTVEVEVVLEDGAMGRAIVPSGASTG
                     AFEAVELRDGDKGRYLGKGVETAVANVNEIIAPEIEGMDAFDQPAIDAIMIELDGTPN
                     KGKLGANAILGVSMAVARAAADEIGLPLFQYLGGVNAKQLPVPMMNILNGGEHADNNV
                     DVQEFMILPVGACCFKEGLRMGAEVFHSLKKVLGEKGLACGVGDEGGFAPNLGSNREA
                     LELIVEAITKAGYKPGEDVMLGLDVAATEMYNKETKKYVLAGEGKELTAAEMVALYED
                     WSNNFPIITIEDGLDEEDWDGWKLLTEKLGNKLQLVGDDLFVTNTERLEKGIENGVAN
                     SILVKVNQIGTITETLDAIEMAKRAGYTAVISHRSGETEDSTIADLAVAVNAGQIKTG
                     APSRTDRVAKYNQLLRIEEMVGEQARYCGLKSFYNLKK"
     gene            20893..21117
                     /gene="secG"
                     /locus_tag="PC512_002569"
     CDS             20893..21117
                     /gene="secG"
                     /locus_tag="PC512_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HDF2442304.1"
                     /translation="MSNILMGVQVVLGILLVISIMPQDSKNALPSEFGGEGSQAYFKP
                     KGKQAFLARVTKITAVLFFINALALLIVKK"
     gene            complement(21501..22439)
                     /locus_tag="PC512_002570"
     CDS             complement(21501..22439)
                     /locus_tag="PC512_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HDF2442305.1"
                     /translation="MENLILSINVVLPLFLTMSLGYVLKKLGLFDTHTLNKMNNVCFK
                     SFLPLLLFFNIYNTDLDGSLNFRLMAVAVIIIFSIFLILVFIIPKIEKDNKTRGALIQ
                     GVFRSNFVIFGIPVTISLFGDKSIGVTSLLIAVIVPMFNVLSVVILEIFRGGKVNIKH
                     MIKSVLTNPLIIASFIGLTMLILNINIPTFLHKTIGDISKIATPLSLIILGGSFSFSA
                     IKGHINPIILGVCGKLILVPAIFLPISIFLGFRNVELASLMIMLSAPTAVSSFTMAQQ
                     MDSDSELAGQIVVFTSGFSIITVFLIIFILKQNNLI"
     gene            complement(22427..22825)
                     /locus_tag="PC512_002571"
     CDS             complement(22427..22825)
                     /locus_tag="PC512_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDF2442306.1"
                     /translation="MIKKIEHVVITNNNIENYINFYKKFGFSSKEMSKNYKLNARNIK
                     INLNIKGYKFLPYVKNLQASRDNLCFKINTNIDEPKKYLEQNEIQIKRGIVECTGVFG
                     NMKSIYLKKTNGNLIELSNHRITESKPWKI"
BASE COUNT         9110 a         2598 c         4417 g         6721 t
ORIGIN      
        1 gaagaagatg aatttgttca agcagcgtat aagggattaa aagaagctgg aatagattca
       61 gaaataactc aatactcatt ctgtacgaat ggaagtcact acgcaggtga ggctggaata
      121 agaactatag gatttggtcc ttctaaggaa aatcttgctc atacaataga tgagtatata
      181 gaattagacc aattattcaa aggtgcagaa ggatattatg gtatattaaa atcagtttat
      241 aaaaaataat taggagatgg ttttgtgaga actttaataa aacatgggct tatagtagat
      301 ggaaataaaa caccagcata tgaaggagat attttaatag aaaacgagaa aatattaaaa
      361 atatcacaag atttaaacga agaagctgac aaagttatag atgcaaaagg tagagttata
      421 tgtccaggtt tcatagatac tcatagccat tcagacctag ttattttagt taatccatat
      481 aatgaggtaa agattagaca gggaattaca acagaagtgt tgggccaaga tggtatatct
      541 atggcccctc tacctcaaga gcatatatct tcttggagaa aaaatttagc aggtctagat
      601 ggtgaaagtg atgaaattga ttggaaatat gaaacaacag agaattattt aaaaatgatg
      661 gattacaatg gggtaggttt aaatgaaact tatttagtac ctcatggaaa cgttagaatg
      721 gaagctatgg gacttgaaga tagacctgct actaaagaag aaattcaaaa aatgtgtgaa
      781 atcacagaga gagaattaaa agcaggagct ataggattgt ctactggact tatatatata
      841 ccttgtgcat actcattgac tgaagaaatt atagagatgt gtaaggtagt agcaaaatat
      901 gacggagtat ttgtagttca ccaaagaagt gaagcagata caattttaac ttcaatggaa
      961 gaaatcatag aaattggaaa acaatcagga gtaaaagttc atttttcaca ttttaaggtt
     1021 tgtggtaaag caaactggaa gtatatacca caagttatag agcttttaga aaaagcagaa
     1081 aaggaaggaa taagagtatc ttttgaccaa tatccatatg cagcaggaag tacaatgctt
     1141 ggagtagttt tacctccttg ggcacattct ggaggaactg ataagttaat agaaagatta
     1201 agtgatgaaa acgaaagagc aaaaatgaaa aaagatatag caaatggaat agaaggctgg
     1261 gataatttta tagaatttgc tggaatagac caaatatttg taacaagcgt aaaaacagaa
     1321 aagaataaag atacaattgg taagagctta ttagaaattg gaaaaatgag aggaaaagac
     1381 ccattagatg caacgtttga tttattaaaa gaagaagaaa atgcagttgg gatggtagat
     1441 ttctatggat tagaagaaca tataatagga ttcatgaaaa gagacgagca aaatgtgtgt
     1501 acagatggtc ttttagcagg taaaccacat ccaagagctt atggttcttt ccctaaaata
     1561 ctaggaagat atgttagaga gttgaatgtg ttaacaatcg aagaagctgt ttataaaatg
     1621 actaaaaagg cagctacaag ctttagtata aaagatagag gcgaattaaa agaaggatat
     1681 tttgcagata tagttatatt tgacaaggat acagttagtg gttgtgatga ttttatcaac
     1741 tctatgcagt accctacagg tatagattac gtaattataa atggaaattg tgttgttgaa
     1801 gaaggaaaat acaataaaat taaagcagga aaagtactta aaaattaaat cttagcttta
     1861 aggaggaata aatttatgat tttagtgggg aatgggaggc taataagcca agattcttta
     1921 aatccctata tggaagatgg atgtgtagta ataaatgata atctaattga agatataggt
     1981 actacagaag aaatgaaagc taaatatcca gtacatgaat ttatagatgc aggcaagaaa
     2041 ataatcatgc cgggtctaat aaattcacat atgcatatat acagctcatt tgctagagga
     2101 atggcagttc caggaaaacc ttctgagaac tttttagaga tactaaataa tttatggtgg
     2161 agacttgaca aacagcttac actggaagat acaaaataca gtgcatatgc aacgtatata
     2221 gaatgtataa aaaatggtgt aacaacagtt tatgaccatc atgcaagtcc aaatgcaatt
     2281 gaaggcagtt tgtttacaat atcagatgtt gcaaaggatt tgggaattag aacgtgtctt
     2341 tgttatgaag tgtctgatag agatggtgga aatacaatcc aacaaggtat caatgaaaac
     2401 gtaaacttta taaaatacgc tcaaaaagat gatacagaca tgataaaagg aatgtttggg
     2461 cttcatgctg catttacact atctgatgat acattaaata aatgtgcttc agagatggct
     2521 ggtcttgata caggttacca tgtacatgtt gctgaaggac tagcagactt acaatataat
     2581 gtagataaat atggaaaaag ggttttagaa agattcaatg attttggagt actaaaagaa
     2641 aaaacaatag cagttcattg tatatatata agtgcagaag aaatcagtct tttaaataaa
     2701 acaaatacat ttgtagttca taatccagaa tctaatatgg gaaatgcagt tggatgttct
     2761 cctgcaatag agttattaaa aaggggagtt acagtaggat taggaactga tggatatact
     2821 agcgatatgt ttgaatcatt aaaagttgcc aatataattc acaaacatca cttaaaagac
     2881 ccaagagttg gatttgaaga atcacaaaca atgttatttg ataacaatag aaaaatagct
     2941 aaagcttatt ataaaaatga cctaggagta cttaaaaaag gtgcttatgc agatgttata
     3001 gtagttgatt atataccaca tactccattg acagaaaata caataggggg acacactatt
     3061 tttggaatga gtggaagaag cgtagataca actattataa atggaaaggt acttatgaaa
     3121 gatagaaagt taataaacat agatgaagaa agtattttag caaaaagtag agaattaagt
     3181 caaaatctat ggaatagaat ttaaataatt gatattaata tacaagtaag aaacaagaat
     3241 ttagatgtta aaaacagagc ttaaacaaaa ataggaattt aaatgaagta tataaataaa
     3301 aaatatacgg aatagaatat taaattaaat atagaaggga gacccaaaat gtctcgagat
     3361 aaaagcccta aaatagctcc agtagatgaa aggttacctg tatccaaatc ttgggtattt
     3421 tcactacagc acgttttagc aatgtgtgca ggagcagtag cagttcctat gatgatagga
     3481 agtgctgcac gactagatca tgctagtatt gtttttttaa taaatgcttg cttgtttatg
     3541 gcaggtatag gaacactcat acaaagtgtt ggtataggaa atattgtagg tgctaaaata
     3601 ccagtaatag aaggaactag ttttgccgct gtggcaggta tgacagcaat agcctcatca
     3661 tatagtgatt cacaagttgc aatacagaca gtatttggct ctgtaatagt agctggattg
     3721 ttttgtatat tacttgctcc agtatttgaa aaattaataa gatttttccc tagtgtggtt
     3781 actggaacag ttgttatggt aataggtatt tcactatttc cagttgggat aaaatggata
     3841 actgacaaca aattggaagc ggttgaacca aactcattag cattagcttt agcagtattg
     3901 gcaataactt tactttcatt taaattctta aaaggaattt ggaatagtac agctatattg
     3961 gtaggtatag tacttggtac actactttcc atggcagttg gaatggcaga ttttagtgca
     4021 gtaaatggag ttggttggct taacttaaat gtacctttaa aatttggaat gcctagattt
     4081 gaaccatctg caatactatc attgtgtttg attatgttgg tacttatgac ggaatcagtt
     4141 ggtaatatga tagctattca tgaaatggta gacaaagaag taacaggtaa aaatattaaa
     4201 agaggtctat ttggagatgg aatatctaca gcattatctg gaatattcaa ttcatttcca
     4261 ataactccat ttggtcaaaa tacaggaata gtaggtctta caggtataaa atcaagattt
     4321 atagcagttt acgcaggggt tatattgcta gtacttggat tcttaccaaa atttgcagca
     4381 ataataggag caatacctaa gcctgttctt ggaggcgtag gatttgcaat gtttggaatg
     4441 gtaatggttg gaggagtaaa aactttaagc aaagtgaaat ttgatggaac taaaaatggg
     4501 gttatagtag cagttagtgt tggtttgtct atgataccac taacaaatcc tgatttctat
     4561 cataatttcc caacttgggt acaaacaata ttccatagtg gaataacaac aggtagttta
     4621 tcagcagtgc ttttaaacat attcttcaat gaactaggtt ctaaaaaaga aaaaaataat
     4681 aaagttgaag aagcaaaata aaaataaaac aagtaaaaat ctatattgac ttaaagtcat
     4741 taagcattaa taaaaataat tcagagatat taataattca acaaaactat cttatatttt
     4801 aaataatata aaaaagtaaa taaataacga atacaaataa aagaatacaa tctaaatatt
     4861 aaaaatattt aatttaaggg agagataata atatggctaa tttaaaagtt aatttatatg
     4921 gaatggaatt tttaaaccca attatgacag cggcaggacc tggagcaaaa gatggtgctc
     4981 tctgtcaaga ggcagcaaaa ggtggagcag gagctatatg tacaaaaact atatctgtat
     5041 taccagctga tgtaccaaga ccatgtatgg caaaaactaa tagtggtttt ttaaacacag
     5101 aattatggtc agagcttcca aaagagcaat ggatagagga agaatacaaa aaggtaaaag
     5161 aaacagggct tccagtaata gtaagtatgg gatattcagc agagcaaata gctgaggttg
     5221 ctcctttagt aaagccttat gcagatgcag ttgaattatc tactcattat gtaggtacag
     5281 acgttgcacc aatagtaaat gctttaaaag ctgcaaaagc tgttttagat gtaccagtat
     5341 ttatgaaaat gagtcctcat actgacattc aaactattgc aaaagctgtt gaagaagcag
     5401 gtgcagatgg acttgtaatg ataaactcat ttggaccatg tatggcaata gatgtaaata
     5461 caggataccc tataatggga agtaaagctg gatacggatg gttatcaggt gcaccaataa
     5521 gacctctagc aataagatgt atatatgaag cttctcaagt tgtaaatata ccaataatcg
     5581 gtgttggtgg aatcacttgt ggaaaagacg tggctgaaat gatgatggct ggagcaagtg
     5641 ctgttcaagt atgtacagaa gcaatcctta aagggccttc tatctatgga aaaattgcta
     5701 aagaattaaa tgaattttta gatgagaatg gatatgctga tgttaatgaa ataaaaggat
     5761 taactcataa gaaaatggca gctagagggt ttagaactca ttcagtagct ccagtagtgg
     5821 atgataacaa gtgtatcaaa tgtaagcaat gtgtaacaag ctgtgtatac gaagctttag
     5881 aagttacaga taagttgaac atagatgcag acaagtgttt tggatgtgga ttatgtgtaa
     5941 ctagatgtcc aaaaggagct ttaagcatct gctacaatca agtagaagct atgaatgagt
     6001 aataattata tagaattttg gtaattaact tagagtaata ggtattagga taataaaata
     6061 tatcagataa acaaacacgc attatgcatt aataatacag tctaaagtta ataattttat
     6121 tatattgatt taactaaata ttagtttagc tgaatattaa tttaattagg tattggttta
     6181 atcttaatat agatttacta cgtataagtg aactaactag attactttaa gttaattttt
     6241 tcatataaaa taaattgata cattacaagt aaggtggagt ctatatggga attgttttaa
     6301 aaggtgggaa agtagtaaca agtgaaaaaa cttactgtgc agatgtaaga atagaagatg
     6361 aaaaaatagt cgatataggt cttgatatat caaaagaaaa tgatgaaata gttgatgtta
     6421 gtgattctta tgttatacca ggaggtatag atacacacac acactttgac ttagatacag
     6481 gcgttactaa gacagcagat aactttgaga caggaacaaa agctgctata gtaggaggaa
     6541 ctactactat attggatttt gctacacaag ctaaaggatg ttctttgaaa gacggattag
     6601 aagaatggca tgaaaaagct aaggataaat catattcaga ttatggcttt catatggcta
     6661 taacagattg gaatgactcg gtttgtaatg aaatggagga tatggtgaaa gagggagtat
     6721 cttcatttaa actgtatatg gcgtataaag gaagccttca agttgatgat ggtgtaatct
     6781 ttgaagcatt gagaaaagca gaagagatag gagggattat tggtttccat tgtgaaaatg
     6841 gggacataat atgtgaactt gtggataaag caaagtcaga aaataattta tctccaaaat
     6901 atcatcaatt aactagacca gctataatgg aggcagaagc tacatcaaga cttatgaaga
     6961 tagctgaagt tgcaaactct aaagtatatg tagttcactt aagctgtaaa gaatccttag
     7021 aggaggtttt aaaagctaag caaagaggtg tggatgtaat agttgaaact tgtcctcaat
     7081 accttctatt aaatgatgaa ttatatgatt tagatggatt tgaaagtgct aagtatgtaa
     7141 tgtcaccacc tttaagaaat aaagaaaata atgaaatatt atggaatgct attttagata
     7201 atcaaataga cactatagga acagaccatt gttcttttaa ttataaggga cagaaggaac
     7261 ttgggataaa cgatttcagt aagataccaa atggttctcc aggtgtagaa cataggatga
     7321 gtcttttata cacatatgga gtctgtaaaa ataaaatatc tatcaacaag atggtagaag
     7381 taacatcaac taatgcagca aagttgtttg gaatgtatcc taataaagga actatagaaa
     7441 taggcagtga tgcagatata ttagtcttaa atccaaacaa aaaatccaaa atagaagcaa
     7501 aaaaacaatt acaaaatgta gattatacac cttatgaagg gtatgaagtg gattgtcaaa
     7561 tagaacatgt ttatttaaga ggaaaagaag tagttagaga tggagaatta atttgtaata
     7621 ctccaagtgg gagatatata aataggcgtc taacaaaggg ggctagagaa tggtagaatt
     7681 tatattaaat ggagagaaag ttgttgcaaa agaaggcaaa aaacttttag acttccttag
     7741 agaagatatg aatataactt cagttaaaaa tggatgttca gaaggtgctt gtggaacatg
     7801 tatggttata atagatggta aagctactaa agcatgtgta tttaaaactg ataaattagc
     7861 tgggaaaaac ataacaacta tagagggatt atcagagaga gaaagagatg tttttgcata
     7921 ttcttttgct agtcaaggag ctgtacaatg tggattttgt attccaggta tggtaattag
     7981 ttcaaaagca cttatagacg ttaataataa tcctactgaa gatgatataa agaaagcttt
     8041 aaaaggtaat atatgtagat gtacagggta tgtaaaaata attaaagctg tcgatttagc
     8101 agcaaagatt tttagagaaa atatagatgt gccaaaagta aactgtaaag gtctagtagg
     8161 tgaaaatctt cctagagttg atgcagttgg caaagcactt ggatattctg aatatgtaga
     8221 tgatatgaga attgaaggta tgatttatgg ttcagcagtt agagctaagt atcctagagc
     8281 tttagttaaa aaaatagata tagaagaagc aaaagcttat ccaggagttg ttgcagttct
     8341 aacagctaaa gatattccag gaactataaa ggtagggcac ttaaagaagg attgggatac
     8401 tttaatacca gaaggtgaaa taactagata cttaggagat ggaatagttt tagtagcagc
     8461 agaaactaga gaagcgttag aagaggcaaa aaagctagtt aagatagatt atgaggaatt
     8521 aacaccatta agtactacag aagatgcgct tagagaagat gctccaaaga tacacgagac
     8581 aggtaatata cttgttaagg aacatttagt aagaggaaac gctaaagaaa agatagaaaa
     8641 ttcaaaatat gttgtaacta aaagatatac tacacctgct acagaacacg catttttaga
     8701 gcctgaatgt gcagtagctg gtccttatga agaggatgga gtaataatct attcaacaga
     8761 ccaaggggtg tttgccactc aacatgaatg tgcagatatg ttagggctac catatgagaa
     8821 ggtaagagtt ataaacaaaa tggtaggagg aggatttggt ggaaaagaag acatgagtgt
     8881 tcaacaccat gcagccttac ttgcatacca tactaagaga tttgtaaaag tacagttaac
     8941 aagaaaagaa agtattattg ttcatccaaa acgacatgcc acagaaatgg aatttacgac
     9001 agcatgtgat gaaaatggat acttaacagg tatgaaggca acgataatat ctgacacagg
     9061 tgcatatgcc tctcttggag gaccagtgct acaaagactg tgtactcatg cagcaggacc
     9121 atataattat caagatattg atataacagg aacagcagta tatactaata accctcctgg
     9181 aggagcattt agaggatttg gagttacaca gagttgtttt gcaactgaat gtaatctaaa
     9241 tttacttgct gaaatggttg gaatatctcc ttgggagata agatataaaa atgcaataag
     9301 acctgggcaa gttttaccaa atggtcaatt tgcagatgaa ggaacagcaa tggcagagac
     9361 actagaagct gtaaaagaag agtatgaaaa gcatccacgt gcaggtatag cttgtgctat
     9421 gaaaaatagt ggggttggag ttggtatacc tgatgttgga agatgtagat tggtgataaa
     9481 agatggcaaa gtccacataa gaacaagcgc ttcttgtata ggtcaagggc ttggtactgt
     9541 tatgactcaa gtagtttgtg aaactgctag cctacttcct gaaaatgtag tgcatgaagt
     9601 tccagatact catttaacac cagactctgg taatactacg gcttcaagac agacagtatt
     9661 tacgggagaa gctactaagg ttgcgtcaaa taagttaaaa gaagctttag actctggcaa
     9721 aactttactt gatttagagg gagaagagtt ttatggagaa tatgaaagta ttacagataa
     9781 aatgggttgt gacaaagaaa atccagtaag tcatgttgct tatggatatg caacacaagt
     9841 tgtaattctg gatgaaaatg gaaaattgga aaaagtagta gcagcacatg atgttggaag
     9901 agctataaat ccaatcagtt tagagggtca aatagaaggt ggagtagtta tgggtcttgg
     9961 atatgctcta accgaagatt acccagtagt taactctgtt cctacagcta agtttggtac
    10021 attaggttta tttaaatcta cagatatacc agaaatacaa gctttaatag ttgaaaagaa
    10081 caaagattta ttggcttatg gggcaaaagg tgtaggagaa atttgtacag ttcctactgc
    10141 accagcagta caaaatgcct attatgtatt tgataaagaa tttagaactg aactaccact
    10201 acaaaatact ccatatagta aaaaaaagta acaaaaaaaa gaaatattaa ataaaaaaat
    10261 agatgaaatt gtaaataaaa aaatagatga aattgtaaat aaaaaaatag atgaaattgt
    10321 aaataaaaaa atagatgaaa ttgtaaataa aaaaaaccct tttgcataag gtatatttta
    10381 aatgatagaa tatacatata caggagggtt tttcttttat aaaataagtt taataaaatt
    10441 gagaggtgag cagaatgaat tttaataata gtctagaatt aactcagtct cagaagctaa
    10501 taatgactac acaacttaag caatcattat caatattaaa tatgagtaag ttagagttag
    10561 aagaagagat aaaaagagaa gcagagaata acccattagt tgaagtcgag aaaagtgggg
    10621 agataaattg ggaagagtat ataaaagaca tggataggtc aagacgttta gatagaacag
    10681 agataagcta taatcctgat aatgaagtta atctagaaaa tttagttaaa tattcgtcaa
    10741 atttatatga agatttaaaa tttcagataa gcctgtataa acttacagac aaagaattgg
    10801 aagtctgtga gtatataatt gatagtttag atgaggatgg atatttaaga actgaggaaa
    10861 aagtaattgt tgatacctta aagatagatg aagaactttt tgaaaaatgt ttaattagtg
    10921 ttcagcagtt ggaacctagt ggagtagggg caagaagtct ttcagaatgt ctgatgatac
    10981 aaatggctag tttaggaata tataatgaaa ttttagagga aatcgttaca aaagacttaa
    11041 atttaattgc aaataataaa tacaaagaga taagtaaaaa gtacaatatg tcattacaaa
    11101 aatgtgttga actaataaac ataattaaga cattagaccc aaaaccagga agaacttgtt
    11161 cagtagagaa aagtgtatac attcaacctg atgtaacagt agaaaaaatt gatgatgaat
    11221 ttattgtata tttaaatgaa aaagattctt atcaaataag aatcaatagt tattataaag
    11281 acatattaaa aaattcacag tctgatgaaa gtgcaaaaga atttataaaa gaaagactaa
    11341 attcagcaac aggacttatg aaaaatatag agagtaggaa aactacagta cttaagattg
    11401 cagaagagat agtaaaagct caagatgaat ttttgagaaa agggacaaaa tatataaaac
    11461 ctttgaaaat gaaagacata gcagaaaaat tagaatttca tgaatctact ataagtagag
    11521 gtgtaaatgg taaatatatg ttaacacctt ttggtgtata tgaatttaga tactttttca
    11581 gtagtgccat tgagactgag aataatgaaa tggcatctag tacaagcata aaaaaaatta
    11641 taaaggaaac aataaaagac gaaaataaaa agaaaccttt aagtgatgac catatatcta
    11701 agttactaaa agaaaaagga atcaatgttg caagaagaac agttgccaaa tatcgtgaag
    11761 aattaggaat cccatcttca agtaagagaa aagaatacta ataagtaaaa gacaaatatc
    11821 agtatggtaa ggggaaaagg ctaattaaaa gatgaatgta gattgggcta aaaattttat
    11881 gaagtaaaat aatagaatat ggaaaagtat taaaatgcta taagatatta aaaaactggg
    11941 gaacattaaa acattaagat agcaaagaac ataaaaaact aaagaagatt aaaacattaa
    12001 agaacattag agctttgagg aatattagaa ctttaaagaa tattaaaatt tataaaatat
    12061 aaaaatacta aaaagaattg aaaaactggg gaacattaaa atattgtaaa atgctaaaaa
    12121 actagaaaac ataattaaat aagtgcttat aaagaatgat taaattaaat aagtgtttgt
    12181 aaagaataat tagatattag aaaaagaaga atacctagat aaataaacta ttattaaatt
    12241 taataatcat aaaaggaaaa cacagggtat aaataaaaat cttaactaga taaaagtaaa
    12301 cttagttgta gataaaaata actagaaata aaagtaacta gaaataaaat tatttatagt
    12361 aataaatatt agaatgaaaa tataaaaaaa tatatataaa aagccttata taaaaagaaa
    12421 aaatactgtg atttgaaaat ggtggagaaa tattttataa aataaaaaaa taaaaaagtt
    12481 tttgaaaaac tattgaaatc tatacgcaaa tcctataaaa taaaaatatc ttgtgggact
    12541 taaataaaca ctagggacga aaaaagtccc gaaaggaaag caataaggag tatgttatga
    12601 agaacttatt agaaattcaa aagaaattga ttccacaggc aattgaactt atggaaagaa
    12661 gatactctat tttaagacaa atatctttaa gtgaaccaat aggtaggaga acattatcaa
    12721 atgtattaga gattagtgaa agaataatca ggtcagaaac tgagttttta aaagaacaag
    12781 gacttataga cgtagctgta tccgggatga ctatcactaa agaaggttct gatttgttag
    12841 ataaacttaa ggacatcatg agtgacatca tgggattgtc taagttacaa gatagagtca
    12901 gagaaaagct tggaataaaa agggtaatat tagttcctgg aagctgtgat gaaaatggaa
    12961 gtttactaaa agatgtaact agatatggat gcgagtattt cttaggtatt ttaaaagatg
    13021 gagatatcgt ttcaataaca ggaggaagca ctatgttgga gttttcaaac gttattaaaa
    13081 ctgataagag atacccaaac tctacaatag ttccagctag aggaagtatg ggaactgatg
    13141 tagagatgca atctaataat atagttgctt cgataagtaa gaaattacat tctaattgca
    13201 aacttttaca tataccagat gagttggatg aaagtgcaat gaaaactctt agccaagtgc
    13261 cagagattaa gacaactttg gagtatatta aaagaacaga cattttagtt tttagtatag
    13321 gtagagcaga tgtcatggca aagagaagaa aacttccaga agacaaggtt gatgagatat
    13381 tatctaaaaa tgcagttgga gaagcatttg gatattattt caacaaagat ggagaaatag
    13441 tttacaaact gaacactgtt ggaattgatt tagaaacagt taaacaagta aaagaaacta
    13501 ttgcaatctt tgcaggtact gaaaaagtag aagccttatt agctatatca aatatgcata
    13561 aaaacatggt tcttgtaaca gatgaagaaa gtgcttataa gatattgtca ttattataaa
    13621 agtcaagacc tagcacagag ctagaaaaca tacatttact ttataggagg tagcgaaaat
    13681 ggttaaagta gctataaatg gatttggaag aataggaaga ttagcattaa gaaaaatgat
    13741 ggagcaacaa gataagttcg aagttgttgc aataaacgac ttaacagacg ctaaaatgtt
    13801 agctcattta tttaaatatg atacagctca aggaagattt aacggagaaa tagaagttaa
    13861 agaaggtgct tttgtagtaa acggaaaaga aataaaagta acagcagaaa gaaatcctgc
    13921 tgacctacca tgggctgaat taggagtaga tatagtatta gaatgtacag gattctttac
    13981 atctaaagat aaagctgaag ctcatataca agcaggggct aagaaagttg ttatatctgc
    14041 accagctact ggagatttaa aaacaatagt attcaacaca aacagtgata tattagatgg
    14101 ttctgaaaca gttatatcag gagcttcttg tactactaac tgtttagctc caatggctaa
    14161 agtattaaat gataaatacg gtatagaaaa aggattaatg actactatac atgcatacac
    14221 taatgaccaa aatactttag atggtcctca tccaaaaggt gatttaagaa gagctagagc
    14281 tgctgctgga aacatagttc caaacactac aggagctgca aaagcaatag gcttagtaat
    14341 accttcatta aaaggaaaat tagatggggc agcacaaaga gtaccagttg taactggttc
    14401 aataactgaa ttagtttgta cattaggaaa aaatgttaca gttgaagaaa taaatgcagc
    14461 tatgaaagaa gcttcaaacg aatctttcgg atatactgaa gaaatgttag tatcttctga
    14521 cataatcgga ataagctatg gttcattatt tgacgctact caaacaaaag ttatggaagt
    14581 agatggaaaa caattagtta aagttgtttc ttggtatgat aatgaaatgt cttatacttc
    14641 tcaattaata agaactttag gatactttgc acaattagca aaatagtcag ttttgagaaa
    14701 atagaaaagt agattgacaa agtccgagtt tgtagtttaa tactacggac tcaggacttt
    14761 ttttaagaaa aaatatataa aatacaccta aataatgtta catactatat ataaaaatat
    14821 gataatatga tatatttaat agggtaaaag tatgtactat attatacttg gcaataaaaa
    14881 attactttat taaaaggaga gatatttatg tcaatgctta acaaaaaaac tatagaagat
    14941 attgatgtgt gcggaaaaaa agtattagta agatgtgact ttaatgtgcc attacaagat
    15001 ggtgtaatta ctgatgaaaa tagattgaac ggagctttac caactattca atatttaatt
    15061 tctaaaggtg cgaaagttat attatgctct cacttaggaa agccaaaagg agaagctaag
    15121 ccagaattat ctttagcacc agtagcaaag agattatctg agatgttagg aaaagaagtt
    15181 gtatttgcag cagacgataa tgttgtagga gaaaatgcaa agaaagcaac tgaaaaaatg
    15241 gaaaacggag atgtagtatt attagaaaat actagatata gaaaagaaga aactaaaaac
    15301 gaagagaatt tctctaaaga attagcatca cttgctgaaa tatttgtaaa tgatgcgttt
    15361 ggaactgctc atagagcaca ttgctcaaca gttggtgcag gtgagttctt acaagagaga
    15421 gtttgtggat acttaattca aaaagaatta aaattcttag gagaagctgt tgcaaaccct
    15481 gtaagaccat ttacagctat acttggagga gctaaagttt ctgataaatt agctgttata
    15541 aacgaattat tagaaaaagt tgataatcta ataataggtg gaggaatggc ttatacattc
    15601 ttaaaagctc agggttatga agtaggaact tctttacttg aaatagataa agttgaatat
    15661 gctaaagaaa tgatggaaaa agctaagaat aagggtgtta acttattatt accagtagac
    15721 gttgttatgg cagaccactt tgcaccagat gctactccaa tagtaacaga agatgctaat
    15781 gtaaaagaag attacatggg actagatatg ggacctaaga ctatagcaaa ctttgtaaaa
    15841 actataaaag aatcaaaaac tgtagtatgg aatgggccaa tgggagtatt tgaatttgaa
    15901 aactttgcaa atggtacatt atcagtagct agagctatgg cagagttgac tgatgcaact
    15961 actgtaattg gcggtggaga tagtgcagca gcagttaatc aattaggatt tggtgacaag
    16021 atgactcacg tatcaacagg tggaggagca tcactagaat ttttagaagg taaagaatta
    16081 ccaggtattg cagcattaga taataaataa actaatatat agaggagatt gtaaaatgag
    16141 aaaacctata attgcaggaa actggaaaat gcataaaaca ataaaagaag ctttagaatt
    16201 tgtaaatgaa gttaaagata aagtaaattc tgataaagta gaagctgtta tatgtgcacc
    16261 atttacttta ttaaaggatt taaaagaagc tactaagggt acaaatataa agataggtgc
    16321 tcaaaatatg cactttgaag aaaaaggagc atttacagga gaagtttcac ctcttatgtt
    16381 aaaagaaata gatatggact atgttgtaat aggacattca gaaagaagac aatacttcaa
    16441 tgaaactgat gaaactgtaa acaagaaagt tttaaaagca ttagaagtag gaatagaccc
    16501 aatattatgt gttggagaaa ctttagaaca aagagaagct ggaaaaacta aagatgtttg
    16561 taaagttcaa gttgaaaaag ctttagaaaa tgttcttaaa gatgatttag caaaagtagt
    16621 tgttgcatat gagccaatct gggctattgg aactggtaaa actgcaactg ctgaagatgc
    16681 taatgacgtt atatcttata taagagaagt tataaaagga ttatatggag aattagctaa
    16741 tgaagttaga atacaatacg gtggaagtgt taaaccttca aatgtagccg aaataatggg
    16801 tcaaagtgat atagatggag ctttagtagg tggagctagt ttagctagta atgattacct
    16861 agaccttgtt aatttctaag gagtgaaatg atgaaaaaac cagttgcttt aattattatg
    16921 gacgggtttg gatacaataa ggatgttaag ggaaatgcaa ttgctgagtc caaaactcct
    16981 aatttagata gaataaaaaa agagtatcca aacacattga taaatgctag tggtcttgat
    17041 gttggtctac ctgatggtca aatgggaaat tcagaagttg gacacactaa cataggtgca
    17101 ggtagaatag tatatcaaga tttaactaga ataacaaaat ctataaaaga tggtgacttt
    17161 tttactaata aagttttatg tgaagcaatg gataatgcaa aagaaaattc tcttcatgta
    17221 atgggacttt tgtctgatgg aggagtacat tcacatatag accatcttaa ggctataatc
    17281 aaaatggcaa aagataaagg cgtacaaaag gtgtatgttc acgcatttac tgatggtaga
    17341 gatactgacc ctcaaagtgc attagaatat gccaaagaag tacaagctag tatggatgaa
    17401 attggagtag gtgaatttgc tacagtttct ggtagatact acgctatgga tagagataag
    17461 agatgggaaa gagtagaact tgcatacaat gccatggtta gaggtattgg tgaaaaagca
    17521 aattctattg aggaagctat tcaaaactct tatgatgatg gaaaaaatga tgagtttata
    17581 atgccaacag ttattatgaa agatgataaa ccagttggaa gtataaagga aaatgattca
    17641 attatattct tcaactttag accagataga gctagacaaa taactagagc tttagtttgt
    17701 gaagagtttg atggatttaa aagagaagat attaaaaact tctttgtatg cttaacagag
    17761 tacgatataa ctatagagaa tgtgcatata gcatttggac ctcaatcttt agccaacact
    17821 ctaggtgagt atctagctaa aaatggaaaa actcaactta gagctgctga aactgaaaag
    17881 tatgcacatg taactttctt cttcaatggt ggagtagaag agccaaataa aggtgaagaa
    17941 agactattga taccttctcc aaaggttgca acttatgatt taaaaccaga aatgtcagca
    18001 tatgaattga cagataaagc tttagataaa ttaggagaag ataagtttga ctttatagta
    18061 ttaaactttg caaatcctga tatggtaggt catacaggaa gtatagaagc ggctataaag
    18121 gctgttgaaa ctgtagatac ttgtgtagga agattgatag ataaaatagt agagttaggt
    18181 ggaagtgcaa taataactgc tgaccacgga aatgctgaat atatgttaga cccagaaaca
    18241 ggaaaaactg taacggctca ctctattaat ccagtaccat ttattgtagt tggtcaagaa
    18301 tatgaaagtg caaaattatt ggatggagga agattatctg atatagcacc gactgtttta
    18361 gatatgatga agttagaaaa gccagaagaa atgactggtc attcacttat ttcaaaatag
    18421 tcgattctga taagtagaga ataatatata aactacaata taaatttaaa aataatgcag
    18481 tttaggttta ttttgtaaag tttagacttt atgacagaag atttagattt tgtaagtttt
    18541 ggatattgta aggtgtagat gaagatatat tttataaaat ttacaagata gacaatttat
    18601 aaaataaaaa attataatat agataataat gtaaataatg atataaataa taacaagata
    18661 gacaataaca atataaataa taataattaa tatatattat ataagcaaaa attttagaat
    18721 cattagttgt acattttatg tttaatgttt taaatctagt tataatattt gtgtatttaa
    18781 gattggtttt ggattttaga caagtttttt tatattatat aaattaaaat attataaaaa
    18841 ataaaataaa aataggaact tttacaaatt tacccatcaa ataaatttgt acctaatttt
    18901 caaaagcaac tttatgtact ataatataga aagtagatta aaatagtaga cggatgttta
    18961 cagtaaatga aaatttaact aatagaaaat cgaagggaga tatacaaatg tcagttattg
    19021 aattagtata tgctagagaa gtattagact caagaggaaa tccaactgta gaagttgaag
    19081 tagtattaga agatggagca atgggaagag caatagttcc atcaggagca tctacaggag
    19141 cttttgaagc tgttgaatta agagatggag ataagggaag atacttagga aaaggtgtag
    19201 aaacagctgt tgctaacgta aatgaaataa tagcacctga aatagaagga atggatgcat
    19261 ttgaccaacc agctatagat gcaatcatga tagaattaga tggaactcca aacaaaggta
    19321 aattaggagc taatgctata ttaggtgttt caatggcagt agctagagca gctgctgatg
    19381 aaataggttt accattattc caatacctag gtggagtaaa tgctaaacaa ttacctgttc
    19441 caatgatgaa catattaaac ggtggagagc atgctgataa caacgttgat gttcaagaat
    19501 ttatgatatt accagtagga gcttgttgtt tcaaagaagg tttaagaatg ggagcagaag
    19561 tattccattc gttaaagaaa gttttaggag aaaaaggatt agcttgtggt gtaggtgacg
    19621 aaggtggatt tgctccaaac ttaggttcaa acagagaagc tttagaatta atagttgaag
    19681 ctataacaaa agctggatat aagccaggtg aagacgttat gttaggtctt gacgttgctg
    19741 ctacagaaat gtacaacaaa gaaactaaaa aatacgtttt agcaggagaa ggaaaagagt
    19801 taactgctgc tgaaatggtt gctttatatg aagattggtc aaacaacttc ccaataataa
    19861 ctatagaaga tggtttagac gaagaagatt gggatggatg gaaattatta actgaaaaat
    19921 taggaaataa attacaatta gttggtgacg acttatttgt tactaacaca gagagattag
    19981 aaaaaggaat tgaaaatgga gtagctaact ctatattagt taaagttaat caaataggta
    20041 caataactga aactttagat gctatagaaa tggctaagag agcaggatat actgctgtta
    20101 tatctcacag atcaggagaa actgaagatt ctactatagc agatttagct gttgcagtaa
    20161 atgctggtca aataaaaact ggtgctccat caagaactga tagagttgct aagtacaacc
    20221 aattattaag aatagaagaa atggttggag agcaagctag atattgtgga ttaaaatctt
    20281 tctataactt aaaaaaatag ttattaaaat ggttactaaa aaagattaat gaagagagaa
    20341 tataagatat ttaagctcat cttataagat ataaaagaga taagtgttaa ttgatttttc
    20401 aattcactta tcctttttta tattttatta cttaatttta ttcatagatt cagaaaaaat
    20461 atgaataaat gtttctatct catttttatc taattgcata ggaggttttt attaaaaaat
    20521 aaaagtgaag acatattttg atttaatcat aattgtcatt aaagtattat tgctaaatgt
    20581 ggattattta ttttaaatta tgttgaaatt aaaagttata tcaatatttt aaaatgattg
    20641 ttttattttg gtggctattt ataatatata caatgagagt agattatttt aagtgttaat
    20701 ttatgcatta atttaaatag ttttctcttc taagttttat tcatttttat attgagaata
    20761 tagtaatata ttatagtaac aatatatttt tttgtatgtt atttatagca taatagtctt
    20821 gaaatggcta tattattgtg atacactaaa gagtaatgaa atttaagtaa taaacagata
    20881 ggaggggcaa gaatgagcaa cattttaatg ggtgtgcaag tagtactagg gattttacta
    20941 gtaattagca taatgcctca agattctaag aatgctttac cttcagaatt tggtggagaa
    21001 ggaagccaag cttactttaa accaaaagga aaacaagcat ttcttgctag agttacaaag
    21061 ataacagcag tattattttt tataaatgca ttggcattac ttatagttaa gaagtagtga
    21121 tattgttgaa taactggcca ttatttaatt agtgcatttg ctagacattt aaaaattaaa
    21181 tttagttttt aataaaagta catcaacata aaaagtacgt aaaataaaag ctggactaat
    21241 gattttatat gattagtcca gtttttattt tatagattga ctatttgttg gcgtttatta
    21301 tttgtattta tatattgttt gtatttatat atttttttca aactaaaaaa tatatagcaa
    21361 cactactttc accatgttta atgagataat atacacaaag ttatattata tagtaaaaat
    21421 agtataataa tatgttttta cgcaattaaa tcgattttat atatgtttct cataatacca
    21481 atttgtgtta tcaaatatca ttaaataaga ttattctgct ttaaaataaa tattattaaa
    21541 aatactgtaa ttatagaaaa tccagaagta aatactacaa tttgtccagc taattcactg
    21601 tcagaatcca tctgttgtgc cattgtaaat gaagaaactg cagttggagc agataacatt
    21661 atcataagtg aagctaattc tacatttcta aatccaagaa aaatgctaat tggtaaaaat
    21721 atagcaggta caagtataag ttttccacat acgcccaata taatggggtt tatatgcccc
    21781 tttatagcag aaaaactaaa agagccacct agaattataa gtgataaagg agtagctatt
    21841 ttagaaatat caccaatagt tttgtgtaaa aatgtaggta tattaatatt taaaattagc
    21901 attgtcaatc ctataaaaga ggcgattatg agtggatttg ttaagacgct tttaatcata
    21961 tgttttatat ttactttgcc acctctaaaa atttcaagaa ttacaacaga taatacatta
    22021 aacataggta caataactgc aattaataaa gatgtgactc caatactctt atcgccaaat
    22081 agtgaaattg tcacaggaat accaaatata acgaaattgc tacgaaatac accttgtatt
    22141 aatgcacccc ttgtcttatt atctttttca attttaggaa taataaagac taagattaag
    22201 aagattgaaa aaataattat aacagctaca gccataagcc taaaattaag agaaccatct
    22261 aaatctgtat tgtatatatt aaaaaataat aataatggca agaaagactt gaagcagaca
    22321 ttattcattt tatttaaagt atgagtatca aatagaccta atttttttag aacatatcca
    22381 agtgacattg tgagaaacaa aggaagaaca acatttattg ataggattaa attttccaag
    22441 gtttactctc cgtgattcta tgatttgata attcaattaa atttccatta gtttttttca
    22501 aataaataga tttcatatta ccaaagacac ctgtacattc tacaattcct cgcttaattt
    22561 gaatctcatt ttgttctaag tatttttttg gctcatcaat atttgtgttt attttaaaac
    22621 ataagttatc tctacttgct tgtaaatttt taacataagg taaaaattta taacctttta
    22681 tgttaagatt tatcttaata tttctagcat taagtttata atttttgctc atttctttag
    22741 atgaaaaacc aaatttttta taaaaattga tataattttc tatattatta ttagtaatga
    22801 ccacatgttc tatttttttt atcatggcaa ctccttaaga ttttat
//
LOCUS       DAMJVG010000060        22513 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.060, whole genome shotgun sequence.
ACCESSION   DAMJVG010000060 DAMJVG010000000
VERSION     DAMJVG010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22513)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22513)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22513
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.060"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            158..832
                     /gene="fsa"
                     /locus_tag="PC512_002572"
     CDS             158..832
                     /gene="fsa"
                     /locus_tag="PC512_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HDF2442307.1"
                     /translation="MQLILDTGNVEEIKELCTCLPIDGVTTNPSIVSKEKKNFKQLIN
                     EIGEIIGEDMPIHAQVLSTKYEEILEEALYISSLRKNIYVKIPVTQDGLRAIKDLHRK
                     GVKITATAIFTAHQGFLAAKAGANYIAPYVNRLDNISGDGVAMVSELIKIIDTYKMDT
                     KVLAASFKNAQQVIELMQHGVHSVTVPYDICKSMMNHPLTDWSVDKFIEDWENTFGKG
                     SKTNNI"
     gene            complement(954..2348)
                     /locus_tag="PC512_002573"
     CDS             complement(954..2348)
                     /locus_tag="PC512_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HDF2442308.1"
                     /translation="MGIILKPKQFYMTVIATIILYFSLNYSFNIKFSICLSFLTILIW
                     AVDSVEKTFVALFFVILAFIFNIAPIKVILQFLFTENFYIIILAYIITNAVTKTGVAK
                     IISEKLILNTVNTPKKMILLSYILGILLIFFIPQPFPRVILVSAFYKEFLKEQQITED
                     SKSILLFSIFTASTFTSMFFVNGDTLLNYVVLELGNCNINWGQWAFYMSVPTIITCFI
                     TYFLFTFVFKKELHSIKFISNENLEGNKLHFSYSNLKKEFNLLNKEQKHVFLCLGIMF
                     FMFLTQFIHNINTLIIMSICVLLLLLRKIVGFSTLKEINWKVLIFFIAAFSIGGVLKY
                     SGVVDIMGNYLIKFIPNSSEIISILFLITLTIILNICLGSAVTTSSVVIPLLGSLHIL
                     KENSVTLCLFVYIIVSIQYILPFHHATIMVGHGENLYNSKVIFKYGLTLIPLTYFIII
                     CITFPWWKFIGLEI"
     gene            complement(2426..3772)
                     /locus_tag="PC512_002574"
     CDS             complement(2426..3772)
                     /locus_tag="PC512_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2442309.1"
                     /translation="MKDLTTGHEGKSIFFFAMPMLIGSLFQQLYNTADSIIVGRFIGK
                     EAMAAVSGANPIMFLLVAALMGVSLGFSILVSQFYGSGDLKKVKATIDTTYILLFIGS
                     ILISILGIVFGGPMLKLMNTPESVFAQSKLYLTIIFSGILFSAGYNSVSAILRGLGDS
                     VTPLYFLIIATILNIVLDLTFIVVLRMGVEGVALATIMAQAVSFIISIIYLNKKHEVL
                     KFKIKGIVYDNKIFKDGLRLGLPSGVQQMLFSIGNMALQFLVNSYGTSAMAAFGAGLR
                     IENFISLPIMNLGSAVSTFVAQNIGAGENERVKKGIRESIKMTLVLAVTVIALILLFR
                     ENLIALFNTDKDVIKIGSSYLFIIGPFFLFIGTSFVLSSAMKGAGDSMFALISSIVSL
                     WLGRLPASYMLSKFFGTDGIWMGIPFGWTLGLIVTVIYYKKGHWKTKAIVNHRINE"
     regulatory      4022..4124
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            4218..5594
                     /locus_tag="PC512_002575"
     CDS             4218..5594
                     /locus_tag="PC512_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HDF2442310.1"
                     /translation="MQTTNSSTMQKLFPILTNKNVDMKKEIIAGVTTFLTMAYIIAVN
                     PNILSETGMPAGALVTGTCLAAAFGCILMGVVANLPFALASGMGLNAFFAYTVVLQMG
                     VPWEVALTAVFVEGIIFIVLSVSGVREAVVNAIPKNMKLAVTGGIGIFIALIGLVNSG
                     IVIGDQATLIKMGRFTPAVIITCVGLIIIAVLDKKRVKGSILFGIVVSSLLAWAFAFI
                     NPEYAQKLGIYLPGGLFKFESLAPIAGKIDLGYVLHPTNIGGFLVVVCTFLFVDFFDT
                     VGTLVGVCSKANMLDEKGNVPNVGRALLTDAVATTVGAGLGVSTVTTYVESSTGVIAG
                     GRTGWTAITVGILFLAAMFFSPVFIAIPSCATAPALIYVGYLMLGTVKDIEFDNITEG
                     VPAFVTIACMALTYSIGDGLTLGILTYVFVNIFYNIFGAKKAEDKKHVSVVMIVLAIL
                     FIIKLWLL"
     gene            complement(5708..6853)
                     /locus_tag="PC512_002576"
     CDS             complement(5708..6853)
                     /locus_tag="PC512_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDF2442311.1"
                     /translation="MNTFEQLKISSTLIDGLKKQDITSPTEVQSLVIGNIIQNKDLLI
                     NSQTGTGKTLAYLLPIFEKIDTSKRETQALILAPTHELVMQITNQVELLAKNAELSVT
                     SLALIGEVNIQKQIKNIKAVKPHIVIGSCGRVLDLIKQKKLKSHNIKTIVLDEVDNLL
                     NGKNITCIEDIIRTTLRDRQIIGCSASLTDSTIKICDKLMKEFEIIKTKEKSQINPNI
                     NHSYLLGEIRDKFTFLRKALAATNPKKAIVFVNNEKNIEVLVSKLNYHNYKAIGIFGN
                     MEKEDRKNAINKFKLGKAKILITTDLSARGLDIVDVSHVFNLDFPKSKNEYLHRCGRT
                     ARGNRSGNTISIITKKELDIIKDLQKEFNIVITPKTLQNGELIDIIK"
     gene            7106..7813
                     /locus_tag="PC512_002577"
     CDS             7106..7813
                     /locus_tag="PC512_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2442312.1"
                     /translation="MLKVINVSKSYKNKKVVSSVSFDVNDGELFGFIGHNGAGKTTTI
                     KAIVGIHDFEEGEVLINSKSIKKQPVECKKEMAYIPDNPDLYESLTGIQYLNFIADIF
                     EVAKDKREELIKYYSNKFELNKALGDLISSYSHGMKQKLAIISALIHSPKILILDEPF
                     VGLDPKASFILKEIMREFCDKGGCIFFSTHVLEVAEKICDKIAIIKDGNIIAYGTTEE
                     VKGSNSLESIFMELIEK"
     gene            7860..9455
                     /locus_tag="PC512_002578"
     CDS             7860..9455
                     /locus_tag="PC512_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2442313.1"
                     /translation="MSNLSILIKTNIINEFKLNALKKADGREKQKIMGMMLSVVIIAG
                     LLIFYVTSLSLSLVDILKQINQLEMLLIFGFGLSTLTTIVTSLYKTSSYLFQAKDLDL
                     LTSLPIKESTVLASKILMLVGANYLFSSICMLIPAVVYFLNSDVSITYFPYLILLFLA
                     LPLLPIVASSIIFLFIGQISSRIKYKNLVLIIGSIILMLLYTLLMSRLNSMSVEMLKN
                     SVSISETIRKVYPPIYYFVDALKTGSIVSFLAFIAISIIPFFMFVTLFAKKFKDINAK
                     MSEGYKSKNYEFKGQKTSRPSKALLKKEFKRYTSSFIYFLNSSAGLLFLIVGTILILL
                     FGADKVGELLKLNIDFNLIKIQLLGVFFFIIVMNCTTYCSISLEGKNLWILKSSPIDE
                     REIFWSKILMNFLLNAPLSILCLILVSIRLDFEIQFIIVSICLIVSFSMFVALMGLLS
                     NLLYPNLDWKNEVAVVKRSASMIVTMLVSLAYVIILGGIYVLLGISFLNIYIILASIL
                     TLILDFMIWRIISTKGVRIFKNL"
     gene            9558..10640
                     /locus_tag="PC512_002579"
     CDS             9558..10640
                     /locus_tag="PC512_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HDF2442314.1"
                     /translation="MRKLSKREKDFIQYGFLLFLICITTYLVLTTLDIKLIPKIIRLV
                     NKTYIFLGILTIIVYMIIESIVTHLIINAVQKTKVKFIGIKMATMGFYYNLVTPFASG
                     SQPMQIYALTKYDVSLSKSVAIVTNKTVVFQSTVTVFCGILILLNKSLLMEQVHSVKV
                     LITFGMIMNVSMLLGGLLIVFSPKQVKMIAEVLINFLSKFKTFKFLDSKRDRINHYID
                     DYNYSIKIFIKNVRILVLSILLTVLQLIAYFSIVYCVYKASNLRGVSYVHIMTLQVFL
                     YMAISPIPTPGNVGANEVTFFTMFSNIIPKELLGYSVLLYSGFVYYFILIVSGLFTFG
                     THYTLNSWKKENKVNSNLDKVIEKLN"
     gene            10789..10950
                     /locus_tag="PC512_002580"
     CDS             10789..10950
                     /locus_tag="PC512_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III"
                     /protein_id="HDF2442315.1"
                     /translation="MKQDKQNEKQSEISKIKQSNDNKLEIAQELHVSKNIGNMLGYRI
                     DKKKMNRPS"
     gene            11291..12559
                     /locus_tag="PC512_002581"
     CDS             11291..12559
                     /locus_tag="PC512_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HDF2442316.1"
                     /translation="MEASIHTIASNNLLIIFAIVSITGIICSKLSEIIKVPDVVLYLL
                     VGILIGPSFLKFIDIRGFQIENQLILTFGSAFILYLGGKEISLKVLRNVKISVFLLAT
                     LGVVISAFIMQQVIGFTFGISAMTALLAGTIIASTDPATLVPIFNQVKIKDRVKQTVI
                     SESAFNDATGAILTSAVLAVILSNKFSLGENIYELGTMVIVGVLVGLITGILLLKLVN
                     DKPYGIFKDFAPIISVISVVVAYELSTKLGGSGYMSCFIVGIITGNKKNFKIWLSQKS
                     YDADFYVAETLGTICRMAIFIILGSQVNLAQLSKYFMPSVITVLVLMFIARPLCVLVC
                     TLVDREAKWSKSEILFMMWVRETGVIPAALCGIISAMKVPGYEVISSVVFMTILITLV
                     IQGSTTKLVAKKLGLLEEEVINISEKVSTF"
     gene            12754..13542
                     /locus_tag="PC512_002582"
     CDS             12754..13542
                     /locus_tag="PC512_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HDF2442317.1"
                     /translation="MFTVMDIVQPDTVEEAYSILNKRKTNQVIGGSAFLRMGKKRIGT
                     GIELSKLNLDYIKEYEDYVEIGSMTTFRTLETSSIIKNNFGRIIEDSVKNIIGVQFRN
                     VVTVGATVFSKYGFSDLIVALLSLDTEVELYNIGRISLEEFLNRDYEKDLLIKIYIKK
                     TNKNASYKSLRNAKSDYPILNVSVSKHMEQFKLCVGARPQKATIAKQASEFLSNNEIN
                     EINIDKAVEIASEELTFGSNMRASREYRKAMSKVLLKRAIMEVI"
     gene            13542..13991
                     /locus_tag="PC512_002583"
     CDS             13542..13991
                     /locus_tag="PC512_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster binding
                     domain-containing protein"
                     /protein_id="HDF2442318.1"
                     /translation="MLVKININGKKKSVDIEPEEYLVDTLRKVGNLSVKRGCDTGCCG
                     LCTVLIDKKPTLSCATLTLRALDKEITTIEGLENEVKEFSEVLVKEGAEQCGFCSPGF
                     ILTVLAMKDELENPTDDEIKHYLTGNLCRCTGYMGQLRAIKTYLEVK"
     gene            13995..16259
                     /locus_tag="PC512_002584"
     CDS             13995..16259
                     /locus_tag="PC512_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HDF2442319.1"
                     /translation="MNIVGKGIKKIDGMSITTGKPVYTDDLSAKDALVVKILRSPHAY
                     AKIKDIDTSKAEMVDGVECVLTYKDVPKSRFTLAGQTYPEPSPYDRLILEDVVRYVGD
                     EVAIVAAIDEKTAIKAMNLIKVKYEVLTPVLDFEEAIGNKTMVHDEDRHCNFDIGMQR
                     EKNIVSHHDYTKGDVEKVLSNCDVVIEETYYTQAQAHAMMETYRAYNYLDHMGRLVVV
                     SSTQIPFHVKRHLSRALEIPASKIRVIKPRIGGGFGGKQTACVEIFSAIVTLKTGKPA
                     KIIYDRKETFNCSTSRHAMRLKVRLGATNDGIIKAIDIKALSDTGAYGEHASTTIGLV
                     GEKTLPMYNKVEATRFIADVVYTNKMPAGALRGYGASQGCFAVESTINMLANKLKMDP
                     TDLRLKNVVTEGETTFAYGKTLNSVDLIKCINKGKELIGWNEKYPCKHLDNGKIRSVG
                     MAITMQGSGIQGLDKSSAEIKLNDCGDYTLMIGSTDMGTGSDTILAQMAAEVLDTSIE
                     NITVISADTDLVPYDPGSYASSTTYVTGMAVVKAAQDLREKIISAGATKLGVEKDEVK
                     FDGIKLTSKKGSTLLFDIAVDSTIGPDTNQLIGLASHGSPVSPPPFIAGFAETEIDTE
                     TGKVDLVNYVAVVDCGTVINKNLAKIQVEGGIVQGIGMALFEEVRYTEKGRMDTNTFM
                     QYKIPARCDIGNVKVDFVETYEPTGPFGAKSVGEVVINTPLPAIQEAVFNGIGVRINT
                     LPITPEKVFMEMNK"
     gene            16399..16710
                     /locus_tag="PC512_002585"
     CDS             16399..16710
                     /locus_tag="PC512_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442320.1"
                     /translation="MAGNLNNMRAVNNFRGDKNILECLVSFEGRSISQRKVRVFFKEK
                     QNQIEIDFAEEEISKLVENVVLNTSYQEMLYDEIEKQLEIDCIGTWMILSKLKDGSRV
                     H"
     gene            16996..17496
                     /locus_tag="PC512_002586"
     CDS             16996..17496
                     /locus_tag="PC512_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HDF2442321.1"
                     /translation="MRKNSINIALTAAITAIYAVLTLSLGFISYGPIQFRVAEIMMLL
                     AFLDKGYIVGLTLGCFLANVIGPYGVPDIIFGTLATFISASMIYITRKLGKQNKSTLV
                     IASLWPTVINSIVVGLMLNVFFGLPLILSMIQVGFGEFVVVTIVGVPFFCFLMKKYKN
                     VINIKF"
     gene            17553..18539
                     /locus_tag="PC512_002587"
     CDS             17553..18539
                     /locus_tag="PC512_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HDF2442322.1"
                     /translation="MSKVKRLTDVWIYINDKQKFTIKELSEEFNLSAKTIQRYLKELN
                     KMGLPIQAEQGRNGGYRVLNNSYIPPVIFTEKEVMIILFALKSLQIYNYKLMEIEINS
                     IMRKVSYERKSSIKVGIENIKRYIGFVANDTNDGDFKSSNVTEFFRASSESLILNIKY
                     KCGNQILEKNVCPIGIYLNKGAWFSPAYDCKSDKIILVHIDNIIDIKRTGESKKIHIN
                     LEEWLHEVYNNLYGNSSTTKKFGEIIYLNVLLTKEGVSKIKDSSWNLDMELNEDGSGI
                     ISTFIKVEDIDCYASILFFIGNNAKVIEPKFLNKLLYDKANELRYFYEENMV"
     gene            18589..19311
                     /locus_tag="PC512_002588"
     CDS             18589..19311
                     /locus_tag="PC512_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein"
                     /protein_id="HDF2442323.1"
                     /translation="MENFNKNAKIIGIGAEGINIINEVEEKIKANMDIEKININQEIE
                     KEYVRSLLDGVDILFLIYSSEDKHIRDIIKAVSYMSNERRVLSIGMDCSEKENKEDLE
                     LGREFKINNDSIFKFVDLMNIMVESISDSCMINIDITDLKEAIVGDKGIKYSFEEFED
                     TKSYSEIADILFDRMEYIGEEFISKKGIVFVEGSPEFSIMELNDLISNIQSKVEESYE
                     VIFSLYIKENLNGNIRVGLLYN"
     gene            19340..21274
                     /locus_tag="PC512_002589"
     CDS             19340..21274
                     /locus_tag="PC512_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2442324.1"
                     /translation="MSENIRGTEYWLMEEFFYQETDTPQIFREESIIALGFDIKINLK
                     KVFSMGKKSEKYINENCNDKDFIKKFMSIKKGDYFLYKAYQNIEEKVKCNVSIGIVEE
                     DFENGYELSHILGHTLPVKWMHNFDTVSNCKVYTSEFYKLNNNDISSYLEIIKSQDKK
                     LLRKRIEESENNKWYLKNYYYKNVDKCVDDEELFIQPINLEQLESLKNIKTDDYILLY
                     NSEKVICENDHTMKSLFGVCQVMEGFDKEKVSALEGGYFFPVRWIEYEKENIDGNAWV
                     IFENNSIVEKYVKRFTNKMPLNTILYGPPGTGKTYNTKQMVYNLVSETSLRNKYYTGY
                     LDYKNNVEFCTFHQSYGYEEFIEGLKSDGEGNFKQEDGILKDISIEACYNALKFEKKM
                     SFELEKDSLTLETIKDRKKKLVLENIEYSESFNFEESENYVLIIDEINRGNVSKIFGE
                     LITLLEDDKRLTKSNQTIVKLPYSKEKFSLPPNLYIVGTMNTSDKSIALLDIALRRRF
                     NFEEIMPDYDLLSIVDGIDIRKMLYTINKRIEFLYDRDHVIGQAYLLAVENINDIVVV
                     FRSKIIPLLQEYFYYDSEKVGLILGGIGRNEKDKYIVYKEKLIASELFKNNNASIMES
                     KVNYCIKQNISSEELKNIYE"
     gene            21267..>22513
                     /locus_tag="PC512_002590"
     CDS             21267..>22513
                     /locus_tag="PC512_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HDF2442325.1"
                     /translation="MSKNIYVKETYEWIRVGNGENELTEIEYEKLLKYLENNNDVLKS
                     NIIDIKYKKLRFINYVGIICFENVILEILPKLSLSDNLVKDREILLQMLSICNKIPIT
                     MNEKIRLSLKNYNLLNFFVMYFIESMQTQMKKGIYFEYINKIENLNVMRGKILLSTYA
                     KEKGISPMKIRCEYDEYSENNFLNQVLKKACISILCRINDNSIQGKIKKILSYFQNVD
                     LIYIDRKKLLDYKFYKNNDRFKDCYLLARLILLNLSMDNSQNNQEAFSILFEINTLYE
                     EYIGILIKSIWDNSFRETYIQDKSKFLLKNEQTGKKNFNLRPDIVLYDLKNEYEIIID
                     TKWKAIEVDSNVFYRSSDIYQMYAYITAYENAKRCILLYPCIQKDKNYSSWKLSESFK
                     GKFIEAKTVRLDDIKNTKNDLKK"
BASE COUNT         8689 a         2370 c         3701 g         7753 t
ORIGIN      
        1 taactatata tttagaattt agtaaataaa aaaattataa aactaagaag gaaaagtaaa
       61 acaataataa aaaataaaaa acaataagca aaatgttgaa aataatacca aatcaatata
      121 taataagaat aaagaaagat taaaggggga tattttaatg caactaatct tagatacagg
      181 taatgtggag gagattaagg agttatgtac ttgtttacca atagatggtg taactacaaa
      241 tccaagtatt gtttcaaaag aaaaaaagaa ttttaagcaa cttataaatg aaattggtga
      301 gattataggt gaggatatgc ctatacatgc tcaagtgtta agtacaaagt atgaagaaat
      361 attagaagaa gcattatata taagtagttt gagaaaaaat atatatgtaa aaatacctgt
      421 aacacaagat ggtttaagag ctataaaaga ccttcataga aaaggtgtaa aaataactgc
      481 tactgcaata ttcactgctc atcaaggttt tttagctgca aaggctggag caaattatat
      541 tgcaccttat gtaaataggc ttgataatat atctggtgat ggagtagcta tggtttcaga
      601 acttataaaa ataatagata cttataaaat ggatacaaaa gtacttgcag ccagttttaa
      661 aaatgcacaa caagttatag aattaatgca acatggggtg catagtgtta cagtaccata
      721 tgatatttgt aaatctatga tgaatcatcc attaactgat tggagtgtag ataagtttat
      781 agaggattgg gagaatactt ttggaaaagg aagtaaaaca aataatattt agtattatgg
      841 taaaagagta gttttgtcca attttacaag aacttatata aaaagatgaa aatatgaatt
      901 ttctttttaa taatttcgtt attatcttaa gttaattcat attttcatct tttttagatt
      961 tctagtccta taaatttcca ccaagggaat gttatacata ttattataaa gtaggttaaa
     1021 ggaatcaaag ttaaaccgta tttgaaaata accttgctat tatacagatt ttcaccatga
     1081 ccaaccatta ttgtagcatg atgaaatggt aatatgtact gtatgcttac tataatgtag
     1141 acaaatagac ataaagtaac actattttcc tttagtatat gtaaacttcc aagtaatggt
     1201 attactacag atgatgtagt gacagcactt ccaagacata tattcaagat tattgtgaga
     1261 gttatcaaaa acaatattga aataatttct gaagagtttg gtataaactt tatcaaataa
     1321 tttcccatta tatctacaac tccagagtac tttaacactc ctccaattga aaatgctgct
     1381 ataaaaaaaa taaggacctt ccaatttatt tcttttaaag tactaaatcc aactattttt
     1441 cttagtaata aaagaagtac acaaattgac attataatta atgtgtttat gttatgtatg
     1501 aactgagtta aaaacataaa aaacattatt cctaggcata aaaatacgtg tttttgttct
     1561 ttgtttagca aattaaattc tttttttaaa ttagaatatg aaaaatgaag tttattaccc
     1621 tcaagatttt cattagaaat aaattttatt gaatgcaatt cttttttaaa gacaaaggta
     1681 aataaaaaat aagttataaa acaagtaatt atagttggaa cagacatata aaaagcccat
     1741 tgaccccaat ttatattaca atttccaagt tctagtacaa cataatttag aagagtgtct
     1801 ccatttacaa aaaacattga tgtaaaggta gatgctgtaa atatactaaa taaaagtata
     1861 gattttgaat cttcagttat ctgttgttct tttaaaaact ccttgtaaaa agcagataca
     1921 agaataaccc ttggaaatgg ttgtgggata aaaaatatta aaagtatacc taaaatatac
     1981 gataaaagaa tcattttttt aggggtattt acagtattta aaattaactt ctcagaaata
     2041 atttttgcga cacctgtttt tgtaactgca ttagtaatta tgtatgcaag aattattatg
     2101 taaaaatttt ctgtaaataa aaactgtaaa ataaccttta ttggtgcaat gttaaatata
     2161 aacgctagaa ttacaaaaaa caatgcaaca aaagtttttt caactgagtc tacagcccat
     2221 atcaagatag ttaaaaaaga taagcatata gaaaatttta tgttgaaact gtaattaaga
     2281 gagaagtaga gaattatggt agctataaca gtcatataaa attgttttgg cttaagaata
     2341 atacccattt ttatattcac ctccataatt tattatatca taatggaggt gaatacaatg
     2401 aatgtgaata cattttataa aaagattatt cattgattct atgatttaca atagctttag
     2461 ttttccaatg tcctttctta tagtagataa ctgtaacaat aagacctaaa gtccaaccaa
     2521 aaggaatacc catccaaatt ccgtctgttc caaaaaattt agaaagcata taagaagctg
     2581 gaagtcttcc aagccataaa gatactattg agcttataag tgcaaacatg gaatcaccag
     2641 cacctttcat tgcacttgaa agtacaaaag aagttccaat aaataagaag aatggtccta
     2701 ttataaataa gtaagaagag ccaattttaa tgacatcttt atcagtattg aatagagcaa
     2761 ttagattttc cctaaatagc aaaattaaag caataactgt aactgctaaa actaaggtca
     2821 tttttataga ttctcgaatg ccttttttaa ctctttcatt ttctccagca cctatgtttt
     2881 gagcaacaaa agtagaaaca gcagaaccaa gattcataat aggtaagctt ataaaatttt
     2941 ctatcctaag accagcacca aaagctgcca tagcagatgt accataacta ttaactaaaa
     3001 attgaagagc catatttcca attgaaaaca acatttgttg aactccactt ggaagtccta
     3061 atctaagtcc atctttaaat attttgttat catatacaat tcccttgatt ttaaatttaa
     3121 gcacttcatg ttttttattt aaataaatta tacttattat aaatgatact gcctgagcca
     3181 ttatagtggc aagtgcaacg ccctcaacac ccattcttag cactacaata aaagttaagt
     3241 ctaaaactat atttagaatt gtggctatta tcagaaaata aagtggagtt actgaatctc
     3301 caagtcctct aagtattgca cttactgaat tatatccagc agaaaataat attccactaa
     3361 atattatagt aagatacaat tttgattgag caaaaacgga ttctggtgta ttcataagct
     3421 taagcattgg gccaccaaat actattccaa gaatacttat taatatagaa ccaataaata
     3481 aaagtatata tgtagtatca atagtagctt ttaccttttt taaatctcct gagccataaa
     3541 attgtgacac taaaatagaa aatccaaggc taacacccat aagcgctgcc accaataaaa
     3601 acattatagg gttagctcca gagactgccg ccattgcttc ttttccaata aatctaccaa
     3661 ctattatact gtcagctgta ttgtatagtt gttgaaataa actaccaata agcataggca
     3721 tggcaaaaaa gaatatggac tttccctcat gacctgtagt taaatctttc accttattcc
     3781 tccaaataaa aaaattatta atttattata gtataatctt aacataaact ttatatccaa
     3841 actataaata aattgtatca aaatatcata tattttttta aaatgtaaag aatataatta
     3901 taatttgaat ttaataaatc aatatttaat ataatcgaat attaatacaa aatcaataca
     3961 atatatacgt atatattgac aaaattaatt atataaatta aaataatatt cgtaaagaaa
     4021 aattcatgtt ttgtactgta taacatataa ttttgacaat atgggtcata agtttctacc
     4081 ggaataccgt aaatattctg actatgtata ctattattta gttaattaaa tatttaatta
     4141 actgaattat gaaggatacg gctcagctta tcaactactg tgtcgttttt ttgtaaaatt
     4201 taataggagg tgttgttatg caaacaacaa acagtagtac tatgcagaaa ctttttccaa
     4261 ttttgactaa taaaaatgtc gacatgaaga aggaaataat tgcaggagta actacttttt
     4321 taactatggc ttatataata gctgtaaatc caaatatttt atctgagaca ggcatgcctg
     4381 caggtgcact tgttacaggt acttgtttag cagcagcatt tggatgtatt ttaatgggtg
     4441 tagttgctaa ccttcctttt gctttagcat caggtatggg tcttaatgca ttttttgcat
     4501 atacagtagt tttacaaatg ggtgttcctt gggaagtagc tcttacagca gtatttgtag
     4561 aaggtattat ttttatagta ttatcagtaa gtggagttcg tgaggctgtt gtaaatgcga
     4621 taccaaaaaa tatgaaatta gctgttacag gtggtatagg aatatttatt gcacttatag
     4681 gtctagttaa cagtggaatt gttattggag accaagccac tcttatcaaa atgggtagat
     4741 ttacaccagc agtaataata acttgtgtag gattaataat tattgctgta ttagataaaa
     4801 aaagagttaa aggttctata ctttttggaa tagtagtgag ttcattactt gcttgggcat
     4861 ttgcttttat aaatccagag tatgcacaaa aattaggtat atatttacct ggtggattat
     4921 ttaaattcga aagtttagca ccaatagcag gtaaaataga tttaggatat gtactacatc
     4981 caacaaatat aggtggtttt ttagtagtag tttgtacatt tttatttgtt gatttttttg
     5041 atacagtagg tacattagtt ggtgtttgtt ctaaagcaaa catgttagat gaaaaaggga
     5101 atgttcctaa tgtaggtaga gccttactta cagatgcggt tgcaactaca gttggtgcag
     5161 gacttggagt atctacagtt acaacttatg ttgagagttc aacaggagtt atcgcaggtg
     5221 gaagaactgg atggacagca ataacagttg gaattttatt cttagctgca atgtttttct
     5281 ctcctgtatt tatagcaatt ccatcatgtg ctacagcacc agctttaata tatgttggat
     5341 atttaatgct tggtacagtt aaggatatag agtttgataa tataactgaa ggtgttccag
     5401 cttttgttac tattgcttgt atggcattaa catatagtat aggtgatggt ttaactttag
     5461 gtatattaac ttatgttttc gtaaatatat tttataatat atttggagct aaaaaggcag
     5521 aagacaaaaa acatgtttct gtagtaatga ttgttctggc aatattattt ataataaaac
     5581 tttggctact ataataggta ttatttaaaa ttttaattta atataaaata aagggctgta
     5641 atttattatc aattgtgatg ataaactaca gctcttttgt atttgttgta tttttgtatt
     5701 tattgtatta tttaataatg tctattagtt ctccattttg taaagtttta ggtgtaatta
     5761 ctatattgaa ctctttttgc aaatctttta taatatctaa ttcttttttt gttattattg
     5821 agattgtgtt accacttcga tttcctctag cagttcgacc acatctatgc aggtattcat
     5881 ttttactttt tggaaaatcc aagttaaaaa catgacttac atccacaata tctagtccac
     5941 gagcagataa atcagttgta attaaaatct ttgctttacc aagtttaaat ttatttattg
     6001 cattctttct atcttctttt tccatatttc caaaaattcc tattgctttg taattatgat
     6061 aatttagttt tgatactagg acttctatat ttttttcatt atttacaaat acaatagctt
     6121 tttttggatt tgtagctgct aatgcctttc taagaaaagt aaatttatcc cttatctcac
     6181 ctaataaata tgagtgattg atgttaggat ttatttgtga tttttccttt gtttttatta
     6241 tttcaaactc cttcataagt ttatcacaaa tttttatagt gctatcagta agacttgcag
     6301 agcatcctat aatttgtcta tctcttaacg ttgttcttat tatgtcttct atacaagtta
     6361 tattttttcc attcaataga ttgtccactt catctaagac aatagttttt atattatgtg
     6421 attttagttt cttttgtttt atcaagtcta aaactcttcc acaagagcca attactatgt
     6481 gtggttttac tgcttttata ttttttattt gtttttgtat attgacctcc ccaattaaag
     6541 ctaaagaagt aacggagagt tctgcatttt tagccaataa ttcaacctgg tttgtaatct
     6601 gcattactaa ttcatgcgta ggtgcaagta taagagcttg tgtttctctt tttgatgtat
     6661 caattttttc aaatataggt aaaaggtacg ctagtgtttt tcctgttcca gtctgtgaat
     6721 taatcaataa atccttattt tgaattatat tccctataac aagtgactga acttctgttg
     6781 gagaagttat gtcttgtttt ttgagtccat ctattagagt ggaacttatt tttaattgtt
     6841 caaatgtatt catattttac tccttatatt ttaataatta tagtcaacta ttttttatta
     6901 tacattgttt attcaaatcg aactatatat tcttttataa ttatgtgtaa tttgaaagta
     6961 aatatcaatt atatttatac ctttatattt ctgatacctt tgcattttat agatttctaa
     7021 aataaacaaa taaaagttgt aattgtttga tatttgttat atattgtata taacaaatat
     7081 caaaactata atatggaggg aaattatgtt aaaagtaatc aatgtatcta aatcatataa
     7141 aaataaaaaa gtagtaagta gtgtctcatt tgatgtaaat gatggagagc tttttgggtt
     7201 tataggacat aatggagcag gtaaaactac tactattaaa gcaattgttg gaatacacga
     7261 ttttgaagag ggagaagtac taataaattc taaatctata aaaaaacagc ctgttgaatg
     7321 taaaaaggaa atggcatata tacctgataa tccagattta tacgagtcat taactggtat
     7381 acaatacctt aattttatag ctgacatatt tgaagttgcc aaagataaaa gagaagagtt
     7441 aataaaatat tattcaaata agtttgaact caataaagca ttaggagatt taatatcttc
     7501 atattcgcat ggtatgaaac aaaaattagc tataatttcg gctttgatac acagtccaaa
     7561 aatcttaatt cttgatgaac cttttgtagg tcttgaccca aaagcttcct ttatattgaa
     7621 ggaaattatg agggagtttt gtgacaaagg tggttgtata tttttctcaa cacacgtttt
     7681 agaagttgct gaaaaaattt gtgataagat tgccataata aaagatggaa atataattgc
     7741 ttatggaact acagaagaag ttaagggaag taattcactt gaaagtatct ttatggaatt
     7801 aatagagaaa taaaatgttt tttatacaat atagtgtcta aagtgaggaa tgataaaata
     7861 tgagcaatct aagtatatta ataaaaacta atataataaa tgaatttaaa ttaaatgcgt
     7921 taaaaaaagc tgatggtaga gaaaaacaaa aaataatggg aatgatgctt tcagttgtta
     7981 taatagcggg tctattaatt ttttatgtaa caagcttaag tctctcttta gttgatatct
     8041 taaagcaaat aaatcaactg gaaatgctac tgatatttgg ttttggatta tcaacattaa
     8101 caactattgt tacatcatta tataaaacgt catcatatct atttcaagca aaagatttag
     8161 accttttgac tagtttacct ataaaagaat ctactgtact agcaagtaag atattaatgt
     8221 tggttggagc aaactattta ttttcttcaa tatgtatgct tatacctgca gtggtttact
     8281 ttttaaattc tgatgtaagt ataacttatt tcccttattt gatattgcta tttttagctt
     8341 taccattatt accgatagtt gcttcatcaa taatttttct atttataggg cagatatcat
     8401 caagaataaa atacaaaaat ttagtattaa tcataggtag cattatattg atgttgcttt
     8461 ataccctact tatgtcaaga cttaattcta tgtcagttga aatgctaaag aatagtgtgt
     8521 ctatttcaga gacgattaga aaagtatatc ctcctatata ttattttgtt gatgctctta
     8581 aaacaggaag tatagtttca tttttagcat ttatagccat ctcaataata ccatttttta
     8641 tgtttgtaac tctgtttgca aaaaaattta aagatataaa tgctaagatg agtgaaggat
     8701 ataagtcaaa aaattatgaa tttaagggtc aaaaaacttc aagaccttca aaagctttat
     8761 taaaaaaaga atttaagaga tatacttctt cgtttatata ctttttaaat tcatctgcag
     8821 gtttgttatt tctaatagta ggtacaattt taatattatt atttggagca gataaagtgg
     8881 gtgagttact gaaattgaat atagatttta atcttataaa aatacaatta ttgggagtat
     8941 tcttctttat aatagtaatg aattgtacaa catactgttc aatttctctt gaaggaaaaa
     9001 acttatggat actgaaatct tctccaatag atgaaagaga aatattctgg tcaaaaatat
     9061 tgatgaattt tttattgaat gcaccactat ctattttatg tctaatatta gtatctataa
     9121 gattagactt tgaaattcag tttattattg tatcaatctg tttgattgta agtttttcaa
     9181 tgtttgtagc attgatggga ttattatcaa atttattata cccaaacctt gattggaaaa
     9241 atgaggtggc tgtagtaaaa agaagtgcaa gtatgatagt tacaatgtta gtatcattag
     9301 cttatgtaat tatacttgga ggtatatatg tattacttgg aatttcgttt ttaaatatat
     9361 atattatttt ggcaagtata cttactttga tattagattt tatgatatgg agaattattt
     9421 ctactaaagg agtaagaata tttaaaaatt tataggtgta tttatgtcaa ataaagactt
     9481 atctttttta gtcttgcaaa taataggtta agtagtatac tatgtatagt gatatgaaaa
     9541 aatttaggag aaaataaatg agaaaattat ccaaaagaga aaaagatttt attcaatatg
     9601 gatttttatt atttttgata tgtattacta cttatttagt attaactact ttagatataa
     9661 aactaatacc taaaattata aggctagtaa ataagactta tatatttctt ggcatattga
     9721 caattatagt atatatgata attgaatcta ttgtaactca tttgataata aatgcagttc
     9781 aaaaaacaaa agtaaaattt attggtatta aaatggctac aatgggattt tactataact
     9841 tagttactcc atttgcatct gggagtcaac caatgcaaat atatgcactt acaaaatatg
     9901 atgtaagcct tagtaaatca gtggctatag ttactaataa aactgtagta tttcaaagta
     9961 cagttactgt attttgtgga attttaattt tgctaaataa gtcattactg atggagcaag
    10021 tacattctgt gaaagtcttg ataacttttg gaatgattat gaatgtaagt atgttgttag
    10081 gtggactact aatagtattt agtccaaaac aagtaaaaat gatagcagaa gttttgatta
    10141 attttttatc taaatttaaa acatttaaat ttttagattc aaaacgtgat agaataaatc
    10201 attatattga tgattataat tattctataa aaatatttat taaaaatgta agaatcttag
    10261 ttttaagtat attacttact gtgttacaat taatcgcata tttcagtata gtttattgtg
    10321 tgtataaagc ctcaaattta agaggagttt catatgtaca tataatgaca ttacaggtct
    10381 ttttatatat ggctatatca ccaattccaa caccaggaaa tgttggagct aatgaggtta
    10441 cattttttac tatgttctcc aatataattc caaaagaatt attggggtac tctgtactct
    10501 tatatagtgg gtttgtatac tattttatat taatagtttc aggtttattt acatttggaa
    10561 cgcattatac attaaattct tggaaaaagg aaaataaagt aaattctaat ttagataagg
    10621 ttattgaaaa attaaattaa taaaataatt agggaaattc tatatataaa tatggtgttg
    10681 aataagctat attatattga gatatttccc ttttttgatt aaaattatag aaatttgaaa
    10741 taataagtaa taaacagaaa aagtgatatt gttttgaaag gagaaactat gaaacaagat
    10801 aaacaaaatg aaaaacaaag tgagatttct aagataaaac aaagcaatga taataaactt
    10861 gaaatagctc aagaattaca tgtaagtaaa aatataggga atatgcttgg atatagaata
    10921 gataagaaaa aaatgaatag accaagttaa tgaaaatgtt gaaaatggta cattttaaaa
    10981 aatatatata atgaaatgtt ttattgttaa atttaaactt attttaatgg gggaaaaagt
    11041 cgaaaaatat ctaaaaagat atggatataa aaaatattaa tatatatata ctataaactt
    11101 gacaaaatca accttttaat aactagcaaa aaatagcaaa attatataag cgttatttaa
    11161 ttgtcaaaaa tgaaagctaa attgcatgtc ctaaaaaaaa tgattgataa catttatttg
    11221 tgtgctataa ttatatagta aaacaataag tatattgcat aatgtatgca aatcgggagg
    11281 agagacggac atggaagcat ctatacacac aattgccagc aataatttat tgataatttt
    11341 tgctattgta agtataactg gaataatttg tagtaagctt agtgaaataa taaaggttcc
    11401 agatgtagtg ttatatttac ttgtaggtat tttaatagga ccatcatttt taaaatttat
    11461 agatattcgt ggatttcaaa tagaaaatca actaatactt acatttggtt ctgcatttat
    11521 tttatattta ggtggaaaag aaataagttt aaaagtattg agaaatgtga agatatctgt
    11581 attcttatta gctactttag gagttgtgat atctgctttt ataatgcaac aagtaatagg
    11641 atttactttt gggataagtg caatgactgc tttactagca ggaactataa tagcatcaac
    11701 agacccagcc actcttgtac ctatatttaa tcaggtaaag ataaaggata gggtaaaaca
    11761 aactgtaata agtgaatcag cttttaatga tgcaacagga gctatactaa catcagcagt
    11821 gttggctgta attttgtcaa ataaattttc attaggtgaa aatatttatg aactggggac
    11881 aatggttatt gtcggagttt tagttggttt aattacagga atactgcttt tgaaattagt
    11941 taatgataaa ccttatggaa tatttaaaga ttttgcacca ataatatctg ttatttcagt
    12001 tgtagttgca tatgaattat ctacaaaatt aggtggaagt ggatatatgt cttgctttat
    12061 tgtaggtata ataactggta acaagaaaaa ctttaaaatt tggttaagtc aaaaatctta
    12121 tgatgcagat ttttatgttg ctgaaacttt aggtactatt tgtcgtatgg caatatttat
    12181 aatattgggt agccaagtta atttggctca gttaagtaaa tattttatgc catctgtaat
    12241 tacagtatta gtattaatgt ttatagcaag accactttgc gttttagttt gtacacttgt
    12301 agacagggaa gcaaaatgga gtaaaagtga aatattattt atgatgtggg taagggaaac
    12361 aggcgtaata ccagcagcac tttgtggtat tatttcagca atgaaagttc ctggatacga
    12421 agtgatttca tctgtagtat ttatgactat actaattaca ttagtaatac aaggaagtac
    12481 tacaaaatta gtagctaaaa aacttggatt attagaagaa gaagtgataa atataagtga
    12541 aaaagtatca actttttaaa gttttgcttt aaaatagtac ctgttaatgg ctattttaat
    12601 attgtctaat gatgattatt gaaatagtca tttttttatg tataagtaat ttacagaatt
    12661 tacatattag acatatttat tatcaaaatt tgttgaagct atgatataat tagttgtatt
    12721 taaaataaga atagcaaata agggaggaaa tttatgttta cggttatgga tattgtacag
    12781 ccagatacag tagaagaagc gtactcaatt ttaaataaaa gaaaaactaa ccaagtaatt
    12841 ggtggaagtg cttttttaag aatggggaaa aaaagaatag gaacaggaat agaattatct
    12901 aaattaaatt tagattatat aaaagagtat gaagattacg ttgagattgg ttctatgact
    12961 acttttagaa cattagaaac aagttccata ataaaaaata attttggaag aataatagaa
    13021 gattcagtta aaaatataat aggagttcag tttagaaatg tagtaacagt tggtgcaaca
    13081 gtattttcta aatatggttt ttctgacttg atagtagcat tactttcatt agatacagaa
    13141 gtagaattat ataatattgg gagaattagt cttgaagagt ttctaaatag agattatgag
    13201 aaagatttac ttattaagat atacataaag aagacaaata agaatgcttc ttataaatca
    13261 cttagaaatg caaagagtga ttatccaatt ctaaatgtat ctgtatcaaa acatatggaa
    13321 caatttaagt tatgtgtagg agcaagaccg cagaaagcta cgattgcaaa acaagctagt
    13381 gaatttctat ctaacaatga aatcaatgaa attaatatag ataaagcagt agaaatagca
    13441 tcagaagaac taacttttgg ttctaacatg agagcatcta gggagtatag aaaagctatg
    13501 agtaaagtac ttttaaaaag agctataatg gaggttattt aatgttagta aagattaata
    13561 taaatgggaa gaaaaaaagt gttgatatag aaccagaaga atatctggtt gatactttaa
    13621 gaaaagttgg taatttaagt gtgaaaagag gttgtgacac aggctgttgt ggtttatgta
    13681 cagttttaat tgacaagaaa cctacattat cctgtgcaac actgacattg agagctttag
    13741 ataaagaaat aactacaatt gaaggtttag aaaatgaagt taaagaattt agtgaagttt
    13801 tggtaaaaga aggagctgag caatgtggtt tctgttctcc tggctttata cttactgtac
    13861 ttgcaatgaa ggatgagctt gaaaatccta cagatgatga aataaagcat tatcttacag
    13921 gaaatctatg tagatgtaca gggtatatgg gacagttaag agctatcaaa acttatctgg
    13981 aggtaaaata gaacatgaat atagttggaa aaggaatcaa gaaaatagat ggaatgagta
    14041 tcacaacagg aaagcctgta tatacagatg atttatcagc aaaagatgct ttggtggtaa
    14101 agatacttag aagtcctcac gcttatgcaa aaataaaaga tatagataca tcaaaggcag
    14161 aaatggttga tggtgttgaa tgtgttttaa catataaaga tgtaccaaaa tctcgattta
    14221 cacttgctgg tcaaacatat ccagagccat ctccatatga tagattaatt cttgaagatg
    14281 ttgtaagata tgtaggtgac gaagtagcta tagtggcagc tatagatgaa aaaactgcaa
    14341 ttaaagcaat gaatcttatc aaagtaaagt atgaagtact tacacctgtt ttggattttg
    14401 aagaggcaat aggaaataaa actatggtac atgatgaaga tagacattgt aactttgata
    14461 taggtatgca aagagaaaaa aatatagtat cccatcatga ttatacaaaa ggtgatgtag
    14521 aaaaagtatt aagtaattgt gatgtagtga ttgaagaaac ttattatact caagctcaag
    14581 cacatgcaat gatggagacg tatagggcat acaattattt agaccatatg ggaagattgg
    14641 ttgtagtaag ttcaactcaa ataccatttc atgtaaaaag acatttatct cgtgcactag
    14701 aaataccagc tagcaaaatt agggttataa aacctagaat tggtggcgga tttggtggta
    14761 aacaaactgc atgtgttgag attttttctg caattgttac tttaaaaaca gggaaaccag
    14821 ctaaaataat ttatgataga aaagaaactt ttaattgttc aacaagtaga catgcaatga
    14881 gattaaaagt tagactaggt gctacaaatg atggcataat aaaggcaata gatataaaag
    14941 cactttctga tacaggagca tatggagagc atgcttctac aactattggt ttggttggag
    15001 aaaaaacttt accaatgtat aataaagttg aagcaacaag atttattgca gatgtggtat
    15061 atactaataa gatgccagca ggagcactta gagggtatgg agcatcacaa ggatgttttg
    15121 ctgttgaatc aactataaat atgcttgcta ataaattaaa aatggaccca acagatttaa
    15181 ggttaaaaaa tgtggtaaca gaaggtgaaa ctacatttgc atatggtaaa actttaaata
    15241 gtgtcgattt aataaaatgt ataaataaag gcaaagaact tattggatgg aatgaaaaat
    15301 atccttgtaa acatcttgat aatggaaaaa ttagaagtgt gggtatggca attactatgc
    15361 aaggttctgg tatacaaggt cttgataagt cttcagctga aataaaattg aatgactgtg
    15421 gagattatac tcttatgata ggttctactg atatgggtac aggaagtgat acgattttag
    15481 ctcaaatggc tgctgaggtt cttgatacaa gcattgaaaa tataacagtt atatcagctg
    15541 atactgactt agttccatat gacccaggtt catatgcttc aagtactact tatgtaacag
    15601 gtatggcagt agttaaggca gctcaagact taagagaaaa aataatttct gctggagcaa
    15661 ctaaactagg tgttgagaag gatgaagtaa aatttgatgg tataaaatta actagtaaaa
    15721 aaggtagcac tttattattc gatatagcag ttgattctac aattggtcca gatactaatc
    15781 aattaatagg tcttgcttct catggtagcc cagtatctcc tcctcctttt atagcaggtt
    15841 ttgcagaaac tgaaattgac acagaaactg gaaaagttga tttagtaaat tatgtagctg
    15901 tagtagattg tggaacggtt ataaataaaa atctagctaa gatacaagtt gaaggtggaa
    15961 ttgttcaagg gattggaatg gcattatttg aagaagttag atacacagaa aaaggaagaa
    16021 tggacacaaa tacatttatg caatacaaga ttccagctag atgtgatatt ggaaatgtta
    16081 aagtagattt tgttgaaact tatgaaccaa ctggaccatt tggtgctaaa tctgttggag
    16141 aagttgttat aaatacacct ttaccagcaa tacaagaagc tgtgtttaat ggaattggtg
    16201 taagaataaa tacactccct attacacctg aaaaagtttt tatggaaatg aataaataat
    16261 tatttatgaa aatttagact agttttacat gttaaacaac cagttatgtc atacctgttg
    16321 aaagatattt aataagtagt tattataata ttatgaattt tacttataaa atacaaaatt
    16381 aaataagggg atgatgtttt ggctggtaat ctaaataata tgagagcagt aaataatttt
    16441 agaggagata agaacatttt agaatgttta gtcagctttg agggtcgttc aataagtcag
    16501 agaaaagtaa gggtattttt taaagaaaaa caaaatcaaa tagaaattga ttttgcagaa
    16561 gaggaaattt ctaaattggt tgaaaatgtt gttttaaata catcatatca agaaatgtta
    16621 tatgatgaaa tagagaaaca actggaaatt gattgtatag gtacttggat gatattatct
    16681 aaattaaaag atggtagtag agttcactga ttttaaaata aattattaga gcctaatttt
    16741 aaggctcttt tttgctgttt ttaattaaca atagaaaact tatctttagt ttgtatataa
    16801 ttttaatatc atatattcta tatatataaa attgaatttg tatgtattat attgtataat
    16861 gtaaaatgaa ttggaaaaat agttcgataa aataatttgt ttttataaaa ttactgttta
    16921 agtttataga ttttgtataa aataaagtta tgttattaat ttttttagaa ataaaacttt
    16981 tactaggaga cagatatgag aaaaaatagt attaatatag cactaactgc agcaattaca
    17041 gcaatctatg cagttttaac attatcattg ggatttataa gttatggacc aatacaattt
    17101 agggtagcag agattatgat gcttttggca tttttagata aaggatatat agtaggtctt
    17161 acattaggtt gttttttagc aaatgtaata ggaccatatg gtgtacctga tataattttt
    17221 ggaacattag ccacatttat aagtgcaagt atgatttata ttactagaaa gttaggtaaa
    17281 cagaataaaa gtactttagt tatagcttct ttatggccaa ctgttataaa ttcgattgtg
    17341 gttggtctaa tgttaaatgt attctttggg cttccattaa ttctatctat gatacaagta
    17401 ggttttggag aatttgtagt agtgacaatt gtaggagtac catttttctg ctttttaatg
    17461 aaaaaatata aaaatgtcat taatattaaa ttttaaatag tgtatagtaa tttaattaat
    17521 tgagagtatt attagtgaaa agaggtgttt atttgtcgaa ggtaaaaaga ttgactgatg
    17581 tttggatata tattaatgat aagcaaaagt ttacaataaa agagttgtca gaggaattta
    17641 atctttcagc taaaacaata caacgatatt taaaagaatt aaataaaatg ggacttccaa
    17701 ttcaagcaga acaaggtaga aatggaggtt atagggtgct aaataatagc tatatacctc
    17761 ctgttatatt tacagaaaaa gaagttatga ttatactatt tgcacttaag tcacttcaga
    17821 tttataatta taagttaatg gaaatagaaa ttaattctat aatgagaaaa gtaagttatg
    17881 aacgtaaaag cagtataaaa gtaggtatag aaaatattaa aagatacatt ggctttgtag
    17941 ctaatgatac taatgatgga gattttaaga gtagtaatgt aactgagttt tttagagctt
    18001 cttcagaatc tctaatttta aatattaagt ataagtgtgg taatcagatt ttggaaaaaa
    18061 acgtatgccc tataggtata tatttaaata agggagcatg gttttcacca gcatatgatt
    18121 gtaaaagtga taaaataata ttagttcata tagataatat aattgatata aaaagaacag
    18181 gagaaagtaa aaaaatacat ataaacttgg aagaatggtt acatgaagta tataacaatt
    18241 tatatggaaa tagttcaact actaaaaaat ttggtgaaat tatttatcta aatgtattat
    18301 taactaaaga aggtgtttct aaaataaagg acagttcttg gaatttagat atggagctaa
    18361 atgaagatgg tagtggaata attagtacat tcataaaggt tgaagatata gattgttatg
    18421 cttcgatttt attttttatt ggaaataatg ctaaggttat agagccaaaa tttttgaata
    18481 agctacttta tgataaggcc aatgagttaa gatattttta tgaagaaaat atggtataat
    18541 atttagaaat gttgaaatta aataattatt aaggagatat acgttataat ggaaaatttt
    18601 aataagaatg ctaaaataat tggtattgga gctgaaggta ttaatataat aaatgaagta
    18661 gaagaaaaaa taaaagcaaa tatggatata gaaaaaataa acataaatca agagattgaa
    18721 aaagaatatg ttagaagtct tttagatggt gtagatatat tatttttgat atattcatct
    18781 gaagataaac atattagaga tattataaaa gctgtttcat atatgtcaaa cgaaagaaga
    18841 gttctatcta taggaatgga ttgttcagag aaagaaaata aagaagattt agagcttggg
    18901 agagagttta aaatcaataa tgatagtata tttaaatttg ttgatttaat gaatatcatg
    18961 gtagagtcta tttctgattc ttgcatgata aatatagata ttactgattt aaaagaagct
    19021 attgtaggag ataaaggaat taagtattct tttgaagagt ttgaagatac aaagtcatat
    19081 agcgagatag ctgacatttt atttgacagg atggaatata ttggtgagga atttataagt
    19141 aagaaaggaa ttgtatttgt tgaaggaagt ccagaatttt ctataatgga attgaatgat
    19201 ttaataagta atattcagag caaggtagaa gaaagctatg aagtaatatt ttctttatat
    19261 ataaaggaaa atttaaatgg aaatattaga gtaggcttat tgtataatta gtatatttta
    19321 gatattaagg agagtgtata tgtctgaaaa tataagaggt acagagtatt ggttaatgga
    19381 agaatttttt tatcaggaaa cagacacacc acagattttt agagaagaaa gcataattgc
    19441 acttggattt gacataaaaa taaatttaaa aaaagtattc agtatgggga aaaaatcaga
    19501 aaagtatatt aatgagaatt gtaatgataa agattttata aaaaagttta tgtcgattaa
    19561 aaaaggagat tattttttat ataaagcata tcaaaatata gaagaaaaag ttaaatgtaa
    19621 tgtgtctatt ggcatagttg aagaagattt tgaaaatgga tatgaattaa gtcatatttt
    19681 agggcataca ctaccagtaa aatggatgca taattttgat acagtttcaa attgtaaagt
    19741 atatacaagt gaattttata aattaaataa taatgatatt agctcatatt tagaaattat
    19801 taagtcacaa gataagaaat tattgagaaa aagaatagaa gaaagtgaaa ataataaatg
    19861 gtatttaaaa aactattatt ataaaaatgt agataagtgt gtagatgatg aagaattatt
    19921 tattcagccc attaatctag aacaattaga aagcctaaaa aatataaaga cagatgatta
    19981 tattttattg tataatagcg agaaagtaat ttgtgaaaat gaccatacaa tgaagagtct
    20041 atttggcgta tgtcaagtta tggaagggtt cgataaagag aaagtaagtg ctttggaagg
    20101 tggatatttt tttcctgtta gatggataga gtatgaaaag gagaatatag acggaaatgc
    20161 atgggttata tttgaaaata atagtatagt tgaaaagtat gtaaaaagat ttactaataa
    20221 aatgccatta aatactatac tttatggacc accaggaact ggtaaaacat acaatacaaa
    20281 acagatggtt tacaatctag taagtgaaac cagtctaaga aacaaatact atacaggtta
    20341 cttagattat aaaaacaatg tagaattttg tacatttcat caatcatatg gatatgagga
    20401 atttatagag ggtcttaagt ctgatggtga aggcaatttt aagcaagaag atgggatatt
    20461 aaaggatata tctatagaag catgttataa tgcattgaaa tttgaaaaaa agatgagctt
    20521 tgagttggaa aaagatagct tgactttaga aactataaaa gacaggaaaa agaaattagt
    20581 attagaaaat atagaatata gtgagagttt taattttgaa gaatcagaaa actatgtttt
    20641 aataatagat gaaattaata gagggaatgt atctaaaata tttggtgagc taataacatt
    20701 attggaagat gataaaagac ttactaaatc aaatcaaact attgtcaaac taccatattc
    20761 aaaggaaaaa ttttctctac ctccaaattt gtatatagtt ggaactatga acacatcaga
    20821 taaatcaata gcacttttag atatagcttt aagaagaagg tttaattttg aagaaattat
    20881 gccagattat gatttattgt ctattgtaga tggtatagat attagaaaaa tgctatatac
    20941 aatcaataaa aggatagagt ttttatatga tagagatcat gttattggac aagcttatct
    21001 acttgctgta gaaaatatta atgatatagt agtagtattt agaagtaaaa taataccact
    21061 tcttcaagag tatttttatt atgattcaga aaaagtaggt ttgattttag gaggaattgg
    21121 aagaaatgaa aaagataaat acattgttta taaagaaaaa cttatagctt ctgagttatt
    21181 taaaaataat aatgcctcaa taatggagag taaagttaac tattgtataa aacaaaacat
    21241 atctagtgag gagctaaaaa atatatatga gtaaaaatat atatgttaag gaaacctatg
    21301 aatggataag ggtaggtaat ggtgaaaatg agcttacaga aattgaatat gaaaaattgc
    21361 ttaaatatct agagaacaat aatgatgtat taaaaagtaa tataatagat attaaataca
    21421 aaaaacttag atttataaac tatgtaggca tcatatgttt tgaaaatgta atacttgaaa
    21481 tacttcctaa attgtcatta agtgataatc ttgtaaaaga tagagagata ctattacaga
    21541 tgctttctat atgtaataaa attccaatta caatgaatga aaaaataaga ttgagtttga
    21601 aaaattataa tctcttaaat ttttttgtta tgtatttcat tgagagtatg caaacacaga
    21661 tgaaaaaagg tatttatttt gaatatataa ataaaataga gaacttaaat gttatgaggg
    21721 gtaaaatatt attaagtaca tatgcaaaag aaaaaggcat ttctccaatg aaaataagat
    21781 gtgaatatga tgagtatagt gaaaataatt tcttgaatca agttcttaaa aaagcatgta
    21841 tatctatttt atgtagaata aatgacaatt caattcaagg caagattaaa aaaattttaa
    21901 gctattttca aaatgtagat ttaatttata tagatagaaa aaaactattg gattataaat
    21961 tttataaaaa caatgataga tttaaagatt gttatttact agctagactt atacttttaa
    22021 atttgtctat ggataatagt caaaataatc aagaggcatt ttctatatta tttgaaataa
    22081 atactttgta tgaagaatat ataggaattt taatcaaaag tatatgggac aattcattta
    22141 gagaaacata tatacaagat aagagtaaat ttcttttgaa aaatgaacaa acaggtaaga
    22201 aaaactttaa tttaagaccg gatatagttt tatatgactt aaaaaatgaa tatgaaatta
    22261 taattgacac taaatggaaa gctattgaag tagattcaaa tgttttttat aggtcaagtg
    22321 atatatacca gatgtatgca tatataacag catatgaaaa tgcaaaaaga tgtatattat
    22381 tatatccttg tattcaaaaa gataagaatt atagttcctg gaaattatca gaatcattta
    22441 agggtaagtt tatagaagca aaaactgtga ggttagatga tataaaaaac acaaaaaatg
    22501 atttaaaaaa gat
//
LOCUS       DAMJVG010000061        22349 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.061, whole genome shotgun sequence.
ACCESSION   DAMJVG010000061 DAMJVG010000000
VERSION     DAMJVG010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22349)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22349)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22349
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.061"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            265..1326
                     /locus_tag="PC512_002591"
     CDS             265..1326
                     /locus_tag="PC512_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate/amino acid:cation symporter"
                     /protein_id="HDF2442326.1"
                     /translation="MRDFLKNYKSSIILLACTIVGAIVGLVLGPKASILKPFGDLFIN
                     ALLMIVVPLVFLSVSSGVASIKNMERFGKIMKGTAIVFMGTTLVIAFLGITSALLFNP
                     SKGLDVSSVKNLMVTQDAETLESKGTLLDQVVSSITVKNFGDLFSSSNLLQLVIFAVL
                     IGTAIAMMGDRGNTIRKLLSEGTEAILKVVSIFMLYAPIGLGCYTATIIGELGSKIIQ
                     GYVRVFVIYSLTAAMYFLLFYSLYAFLSAGKQGFRQFWRNAIKPIATALATSSSSACI
                     PSNLEASKNIGVPDDISETVIPLGINIHKDGSVLAVIIKVAFLSGILGSGMANPATIG
                     QLFITVFVVGVFMAPVAGG"
     gene            1339..1536
                     /locus_tag="PC512_002592"
     CDS             1339..1536
                     /locus_tag="PC512_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:dicarboxylase symporter family
                     transporter"
                     /protein_id="HDF2442327.1"
                     /translation="MLVVSIFGFPVEAIPLLTVITTITDIPNTILNTTGNTVSSMLVS
                     RLVEGKDWLIDKTAITTKKIS"
     gene            complement(1700..2404)
                     /locus_tag="PC512_002593"
     CDS             complement(1700..2404)
                     /locus_tag="PC512_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HDF2442328.1"
                     /translation="MQQGSDYLKKFLEKHIDLLKKIPLFEGIKSDELEEMLECLGVVD
                     KTYTKDSIIFSVGSEVTSIGIMLKGSAHIIKEDIEGNRNIVAELLPGDLFGEVFACTR
                     LHKSNVTVTTTSSCEVLFIKFKSVTGICSSACVFHNRLVENMLQLIAEKNILLHNKIE
                     LLSRKTTREKLLMYFSKQIEQTGSHQFTIPFSRNEMADFLCVDRSSMSRELGKMRDEG
                     LLSFNKNKFEIFYFKK"
     gene            2569..3294
                     /locus_tag="PC512_002594"
     CDS             2569..3294
                     /locus_tag="PC512_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF2442329.1"
                     /translation="MMRKIIKIDEEKCNGCGLCVEACHEEAIGMVNGKAKLLRDDYCD
                     GLGDCLPTCPTNAISFEYREAAEYDEAAVKANMEAKKAQKKTLACGCPGSQSKSINRE
                     VSNSMSISNDIVEIKGSQLNQWPVQIKLVPTNASYLKNASLLIAADCTAYAYGNFHNK
                     FMKNKVTLIGCPKLDEVDYAEKLTEILKENDIKNIVVTRMEVPCCGGIVNAVKTALQN
                     SGKMIPWQIVTISVDGKIVDGEI"
     gene            3354..4946
                     /gene="hcp"
                     /locus_tag="PC512_002595"
                     /gene_synonym="priS"
     CDS             3354..4946
                     /gene="hcp"
                     /locus_tag="PC512_002595"
                     /gene_synonym="priS"
                     /EC_number="1.7.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxylamine reductase"
                     /protein_id="HDF2442330.1"
                     /translation="MEKMFCFQCEQTAGGKGCTINGVCGKKGGTANLQDELTGVLIGL
                     SRATIGNKNRPTSETDKIMIEGLFTTITNVSFDDEAIKRQIEKTEVEKSKLVPRCSDC
                     STTCNRNDNYDMKDLWNDNEDIRSLKSLILFGLRGMAAYAYHAMVLGYTDKDVNEFFY
                     EGLIAVGGDLSIDELLGLVMKTGEINLKCMELLDRANTETYGTPEPTQVSMKIEKGPF
                     IVVTGHDLYDLHKLLEQTKDKGINIYTHGELLPAHAYPKLKEYKHLKGNFGTAWQNQQ
                     KEFDNIPAPILFTTNCLMPVKDSYRDRVFTTEVVAYPGMVHIDEDKDFSSVIEKALEL
                     GGYREDVHMTGINGGDTLTTGFARGTVSSVQDKVVDAVKSGAIRHFLLVGGCDGAKPG
                     RNYYTEFVKQAPKDTVILTLACGKYRFNDLDLGDICGLPRLMDMGQCNDAYSAIKVAV
                     SLANAFECGVNDLPLSMVLSWYEQKAVCILLTLLHLGIKNIYIGPSLPAFLSKNVLDI
                     LVDKFALTPISTPEEDMKKILG"
     gene            5318..6223
                     /locus_tag="PC512_002596"
     CDS             5318..6223
                     /locus_tag="PC512_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HDF2442331.1"
                     /translation="MKNSNFNILAFDGGGLKGALSISILERIVKEYPNLLNNINMFGG
                     TSTGSLIALGLAYGVSPKEIKELYSIENSKYIFNKSYAEILRPKYENKNLKEVLLSIF
                     PEELELKDLNKLVMIPSFYIGNEENAWKPVFYNNMPNSFTKTSKVVDVAMASSAAPVF
                     FPTYNRHVDGGIIATDPSLACIIHAIDSGFKLKNTRLFSIGTGYVYNSIKADTTEWGA
                     IDWIINKEPDLPIISITLEGNSQMSQLFSQKLLGDNYYRLNPKMEKDVAMDDCDALEY
                     LMSLGENCDIKDAFGWIKKKSFYRN"
     gene            6347..7300
                     /gene="msrA"
                     /locus_tag="PC512_002597"
     CDS             6347..7300
                     /gene="msrA"
                     /locus_tag="PC512_002597"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HDF2442332.1"
                     /translation="MIKLATFAGGCFWCMVKPFDKYDGVIKVVSGYTGGHVENPTYQE
                     VCSGTTGHLEAIQITYDDDIISYDELLNIFWKQINPTDDGGQFGDRGTQYKTAIFYHD
                     EEQKNIALESREHLENSKIFDSKIVTDIIPATKFYEAEENHQDYYKKRPLNYNMYYKG
                     SGRYNFVKSHWDGNNINREELKKTLTHIQFEVTQNDMTEVPFENEYYDNNKEGIYVDI
                     VSGEVLFSSKDKFDSGCGWPSFSKPVIDKSIIERSDFSQGMYRVEVRSAKGNSHLGHV
                     FDDGPKELGGLRYCINSASLKFIPRENMEALGYGEYLKLFE"
     gene            7453..8583
                     /locus_tag="PC512_002598"
     CDS             7453..8583
                     /locus_tag="PC512_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2442333.1"
                     /translation="MNLKDFNGKRLKSARIFRAKTIEQLSKETKINKKDLKAFEENKY
                     VPNIENTLKLSNILNFPKEYFYKNENINIVVEDSHFNPQSKLPRVEEISYREKIIIIH
                     KIYSFMENYIKFPKENLPNRKVMSDININDIESLAYKTREFWDLNSTPIVNMVSLLES
                     KGIIISGMNVDRKGATIFTQKQRISKESKYLISLGNDKKSASIRNYTLACELGYIISS
                     ELRIPSKQFSEDEYACAFLLPKESFLKDLTHPEDLDYYVELKKKWIVPISAMIFRAYN
                     LEKINYKKYNYLMNEMDKKGWLIEEPLDKMKGSSPTYLKRAVELLIENKIMSVNSIVS
                     SLEEFGINLYPEDLELLMGLKKGLLSQEVNKKSKVIKFDGKK"
     gene            complement(8700..9668)
                     /locus_tag="PC512_002599"
     CDS             complement(8700..9668)
                     /locus_tag="PC512_002599"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HDF2442334.1"
                     /translation="MAIKPRKISIVGSGHVGSHCGFSLITQGVCDELFMIDIDESKSK
                     AQALDLADAVSYLPHKVHIEKGTFSDCKDSDIVVISVADSSEGPLRRQNTTRLDLLRP
                     TIGMIKSIVKPIVDSGFDGIFVVISNPVDVVTNYIWEKSGFPKNKVIGTGTALDSTRL
                     RRILSEETGIAQQSIQAYSMGEHGDSQMVPWSHVSIGGKPILDMIKDNPSTYSNLDLP
                     SIVEKNKKTGISIINGKDCTEFGIGTALVEIVKAILHNEKKVLPVSTLLEGQYNERNV
                     FAGVPCVIGKDGIEEIIEINMTEYEQNEFNKSCSVLREYIALSKTL"
     gene            10003..10191
                     /locus_tag="PC512_002600"
     CDS             10003..10191
                     /locus_tag="PC512_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442335.1"
                     /translation="MNYHTKEELVEALRVVSSSIINCGKGQKKFSEETSHHTRFKNII
                     EVMYISKSLIMDEISKRD"
     gene            10451..11650
                     /locus_tag="PC512_002601"
     CDS             10451..11650
                     /locus_tag="PC512_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanyl-tRNA editing protein AlaX-L"
                     /protein_id="HDF2442336.1"
                     /translation="MEKLYYTNQYIRDFTAEIIEIKEVENKYHVLLDKTAFFPGGGGQ
                     FGDLGKIESDDVINVYEDGKKIYHVLDKKPIKIHKVKCSIDWDRREDGMHQHFGQHVL
                     SGCFFKTFNANTTGFHLGNEYSTVDIEGNLEEDKIREIELFANEIIRQNIQVETLLPT
                     KKELKKIWLRRDLPNTDEEIRVIKIGDLDTNACCGVHPKSTGELRMIKIKKWEKHKSS
                     TRIEFLAGKRAVDEVLKRDIYLTKICRYLSCSEEDAINGIVNLNSKVEEALIKKRRLE
                     EVVSTYQVKEMIEKANKVGNISVIKKIYDDEDLKYVNKIANKIAEYENSIALLAVKFN
                     DKINLVFACSKNLKDINMGVLLKDAISLIDGKGGGSKVLAQGGGKNNGNLEATLDYAF
                     MKIEKTL"
     gene            11702..12205
                     /locus_tag="PC512_002602"
     CDS             11702..12205
                     /locus_tag="PC512_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2442337.1"
                     /translation="MEQQKDYIELYENEELIEIREARMDDLDTIAKFNYNLAKETEGK
                     ELDMDVLTKGVKALLLDERKGKYHVYTVFDKVVAQIMYTYEWSDWRNGNFLWIQSVYV
                     DKEYRRKGIFNYLFNYIKNICDKDENIVGMRLYVEKENINAKATYESLNMYECDYNMY
                     EYEVIHS"
     gene            12312..12629
                     /locus_tag="PC512_002603"
     CDS             12312..12629
                     /locus_tag="PC512_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442338.1"
                     /translation="MGVLKGMFYVFLFLDLVSIFCFFFNKGKIASNKIVFNAIGVLTF
                     VLCFMLFSYYPNNNLIGKFIASLFFIFGVAGVMLKEKNFLYARLLLTVVIVFSTLRLF
                     VIQ"
     gene            12787..13746
                     /locus_tag="PC512_002604"
     CDS             12787..13746
                     /locus_tag="PC512_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HDF2442339.1"
                     /translation="MIESKKSEKLLLSIIYIIFLVYILMIIRIILFRDVPIYAIFKGT
                     FRNVNLIPFYTIYQFIVDSNLDFMKATVNIIENIGIFIPMGIFLPIVCKNLNKKTIII
                     VIILVSLAFELTQYIFALGSSDIDDVILNSLGGIIGINIYINMNKLFPNDINRFKAII
                     GTSLVLGVIGLGVISKNYHNLLTFKFRPDRKISKILIEENREIIKDINKDTVDIVGTF
                     ESFKKGIITIKAGSNNKVKRPENLIDSDGNIRIYLNENTKLVSYIITKESKMDIVKYE
                     EFDVKNLDLLRRYDTINVWIDKENQPKDKHGIMASKLLIGLYE"
     gene            13861..14646
                     /locus_tag="PC512_002605"
     CDS             13861..14646
                     /locus_tag="PC512_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442340.1"
                     /translation="MEIIKYILYFFIYSFLGWTVESIGCSIASKRIINRGFLNGPICP
                     VYGFGAVIVISLLGRFNNVVIVFLLGMILTTILEYFTGFILETLFHAKWWDYSDKKFN
                     IKGRVCLKNAIYFGVMSVLIIRFIHPFIKYFVSIIPYRILISMAIITTLWTILDLIVT
                     IITLKKLDIKLNLLDDIITDLNDINVKLDKFDRGEIQALFKTINNDELEVREKINKIN
                     SKLDRIESNIILQKRVIKAFPHIKHKKQQEQLEHFKKIINEKR"
     gene            14938..16257
                     /locus_tag="PC512_002606"
     CDS             14938..16257
                     /locus_tag="PC512_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class III-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDF2442341.1"
                     /translation="MSEITSQMISTEEKKYVAKTQKIPYYPVAFKSGDGAMLYDYEGN
                     EYVDFLASAGSANVGHGNKEISQAVKEQMDDITQYTLAYFHSDPPVKLAEKLVEIAPG
                     DNDKKVLYSATGSACIDAAIKLARGYTGRTKIISMCESYHGSTYGAISISALSTNMRR
                     KMGPLLPEVYHFHYPDKNRTAKECLDEIEYAFAHYLPAEEVAAIFIEPIAGDAGIIVP
                     PVEWVQGLSKICKENGILLVSDEIQQGMGRTGKWFGIENFGVEADLIVLGKSVGGGLP
                     LGAVVGRTEIMQSLDAPAHLFTLAGNTTVCVAALKSIEIIEKENLLQKSIEMGDYIKA
                     GFEKLKEKYDIIGEIRGIGLSIGVDIVKGKGSNEKHPDATAKICYRCIQTGLIMIFLG
                     QSTLRVQPPLVITKEQVDKAMNIIDSAIDDYLNGRIGDEVYEVTQGW"
     gene            complement(16332..16760)
                     /locus_tag="PC512_002607"
     CDS             complement(16332..16760)
                     /locus_tag="PC512_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442342.1"
                     /translation="MKDNNNTNKTIQFGEKKASLENNIQKNKNIKLDNTHKVIPYPKN
                     RKKDDKKKGNKKKNTNTSKVNKNNYGHSFFNNKYKYKRKPYVIALYTVILILLAILII
                     TKLTDSTNKGNYSRNTVSDTHKNDIRNIVFNESNNFLICG"
     gene            complement(16851..18227)
                     /gene="hydG"
                     /locus_tag="PC512_002608"
     CDS             complement(16851..18227)
                     /gene="hydG"
                     /locus_tag="PC512_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster radical SAM
                     maturase HydG"
                     /protein_id="HDF2442343.1"
                     /translation="MFINHELINSLLEDAKNSTSDDIEKVLDKADRREKLSYKDIATL
                     LEVEDKKQLDRLFSIAGQIKNEIYGNRVVLFAPLYVSNYCVNECVYCGFSKCNKFKRK
                     KLTMEEIREEVKILEKMGHKRLALEAGEDPKNCDINYILDCLDAIYSTYNENGNIRRV
                     NVNIAATSVDEYKLLKEKGIGTYILFQETYHKPTFIKMHGQSIKNDYYYHLTAFDRAM
                     EAGVDDVGAGVLFGLSDPKFEVLGLMMHNEHLEEKFGVGFHTISFPRLKKAEGMSLED
                     FPHLVSDDMFKKIVAITRLAVPFTGIIMSTRETAEMRNELLKYGVSQISAGSLTGVGG
                     YKAYEDGDNTEQFEVGDHRSPVEVLKELITDGYIPSYCTACYRKGRTGDRFMSLAKSR
                     QIHNVCTPNALTTLNEFLIDYGDEELKIMGKKLIAEEIGKIEREDIRNIVSNNMTALE
                     RGERDLYL"
     gene            complement(18228..19313)
                     /gene="hydE"
                     /locus_tag="PC512_002609"
     CDS             complement(18228..19313)
                     /gene="hydE"
                     /locus_tag="PC512_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster radical SAM
                     maturase HydE"
                     /protein_id="HDF2442344.1"
                     /translation="MTKNKIKYFIDKLYSINSLSFDELLYLIENIDNEEYNFEQNLRN
                     YLYKQASDMRNKHYGNRVYLRGLIELTNYCKNNCYYCGIQSSNKNIIRYRLSLDEILE
                     CCDIGYKIGYRTFVLQGGEDAYFTDDKICEIVSSIKNKYEDCAITLSLGEKSYDSYKK
                     YFLCGADRYLLRHETATDSHYKKLHPPNIELRTRKECLKNLKEIGYQVGAGFMVESPF
                     QNNEDLVRDLLYLKELNPHMVGIGPFIPHHDTIFKDYKHGDLEKTLLMLSITRLLLPK
                     VLLPATTALASINPSGRNAGLLAGCNVIMPNLSPQEFRKQYSLYDNKAFTGQEACEYH
                     QSLEENIKSLGLEVDYSRGDNIEWRRL"
     gene            complement(19349..20557)
                     /gene="hydF"
                     /locus_tag="PC512_002610"
     CDS             complement(19349..20557)
                     /gene="hydF"
                     /locus_tag="PC512_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster maturation GTPase
                     HydF"
                     /protein_id="HDF2442345.1"
                     /translation="MSLNSTPQSVRVHIGLFGKRNAGKSSIINAITNQSAAIVSDIAG
                     TTTDPVFRPMEILPIGPCVLIDTAGLDDVGELGELRIGKSLDVLEKTDIALLVVDCQI
                     GISQEDLSLIEKFNDKNIPHILILNKIDTIKNQSEILNLTKNKVKCPVVSVSSTDKIG
                     IENLKNEIIKVLPKDSTEFKLVSDLIEPNDLIVLVVPIDKAAPKGRLILPQQQVIRDI
                     LDSGAISIVTKEDSLKETLSNLGKKPKLVITDSQVFPQVDKDTPKDIPLTSFSILFAR
                     QKGDLKELINGAYALENLKDGDKILMAEGCTHHRQTDDIGTVKIPNMIRKKTGKNITF
                     EFSSGVSFTEDINKYALVVHCGACMMNRAGMLSRIEKAKSFNVPIVNYGILIAYVKGI
                     LERSLELFNY"
     gene            complement(20572..20823)
                     /locus_tag="PC512_002611"
     CDS             complement(20572..20823)
                     /locus_tag="PC512_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003361768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-only hydrogenase system regulator"
                     /protein_id="HDF2442346.1"
                     /translation="MKKVAVISAILEEPKECQFKFNEVVSGFKGIIKGRMGIPCEEEG
                     VSIVCIAVVGEMDTINSLTGKLGNIPHVSVKTSISKKEV"
     gene            complement(21204..22244)
                     /locus_tag="PC512_002612"
     CDS             complement(21204..22244)
                     /locus_tag="PC512_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HDF2442347.1"
                     /translation="MNLNLTNTINLMKKYLDIPSPAGYTENAVLEIKKDFENLGLDTI
                     LTKKGALIATLPGEDDSNQITISAHMDTLGAIVKEISSDGTLKYHKVGGGCWAAIEGE
                     NCTVITRKGKKIRGSVVFKYASTHIYGQTKAATERNEETMIIRLDEKVFTKQDVLDLG
                     ISVGDFVCLDHRFEATESGFIKSRYIDNKSAVAMVLEICRYFKENNLTPKHTTNFYIS
                     NYEEIGHGVSKCLPEKTKEFVAIDIAPTGPSQTSSEHGVTIVAKDNLSLYDFNLRNKL
                     VDVAEDNNLDYAVDVFTFYGSDASEAIRWGEDVQIACVGPGTNNSHHYERTHIEAIEN
                     TLKLLINYMLKE"
BASE COUNT         8367 a         2685 c         3560 g         7737 t
ORIGIN      
        1 ttttatattg tttgttttat taaaattaat ctagaaaaaa agttttaaaa gcagaatttt
       61 attaatattt atatatagat atgaactatt aataaaacgt taaaaataca aaaaaactat
      121 agaaattgac atatattcca gtatttgcta aagtagctgt tggggaaaat tacaaaaatt
      181 attaatgcgc attagataat ttactttaat ttttttagca tttggggtaa tttataatat
      241 aaagcattag aaaggaaaat ataaatgagg gactttttaa aaaattataa gtcatcaatt
      301 atacttttag catgtactat agtaggggcg atagtaggat tagtacttgg tccaaaagct
      361 tcaatactaa aaccatttgg agatttattc ataaatgctc tattaatgat agtagtacca
      421 ttagtttttc ttagtgtttc ttcaggtgtt gctagtataa aaaatatgga acgatttgga
      481 aaaataatga agggtacagc tatagtattt atgggaacaa cacttgtaat tgcattttta
      541 ggtattacat ctgcattatt atttaatccg tctaaaggat tagatgtatc aagtgtaaaa
      601 aatttaatgg tgactcaaga tgcagaaact ttagaatcaa aaggaacgtt attagaccaa
      661 gtagtatcaa gtattacagt taaaaatttt ggagatttat tttccagtag taatttacta
      721 caattagtta tatttgcagt tttaattgga acagcaatag ctatgatggg agatagggga
      781 aatacaataa gaaagctttt atcagaagga acggaagcaa tattaaaagt agtaagtata
      841 ttcatgcttt atgctcctat agggctaggc tgttatacag ctacaataat tggggaactt
      901 ggaagtaaaa taattcaagg atatgtaagg gtgtttgtaa tttattcact aacagcagcc
      961 atgtatttct tattatttta cagtctgtat gcttttttat ctgcaggaaa acaagggttt
     1021 agacaattct ggagaaatgc tataaaacca atagcaacgg cactagctac ttcttcaagt
     1081 tcagcatgta taccatcaaa tttagaagct agtaaaaata taggagttcc tgatgatata
     1141 tcagaaacag ttatacctct tggaataaat atacataaag atgggtcagt tttagcagta
     1201 ataataaaag tggcattttt atcaggtatt ttaggtagtg gaatggcaaa tccagcaacg
     1261 ataggtcaat tatttataac tgtatttgtt gttggagtat ttatggctcc tgtagcaggt
     1321 ggctgactta ttggtgagat gctcgtggtt agcatcttcg gttttccagt ggaggcaatt
     1381 ccactgttaa cagttataac tactataact gatattccta atactatatt aaatacaact
     1441 ggaaatacag tatcatcaat gttagtttca agattagtag aaggaaaaga ttggcttata
     1501 gataaaacag caattactac aaagaaaata agctaattgt acacttaatt aataaagtta
     1561 ataggtatct taattttaat aaattagata cctattaact ttttaagtaa aaatataaat
     1621 ttaagattca aatatgatat ttataatttg aatcaactaa tatagtatat attgaaataa
     1681 atatgtttaa atatctattt tattttttaa aataaaagat ttcaaattta tttttgttaa
     1741 aagataacaa gccttcatct cgcatcttgc caagctctct tgacatagaa cttctgtcaa
     1801 cacataaaaa atcagccatt tcatttcttg aaaagggaat tgtaaactgg tggctacctg
     1861 tttgttctat ctgttttgaa aaatacataa gcaatttctc gcgagttgtt ttacgagaaa
     1921 gtaattctat tttattgtga agtaaaatgt ttttttcagc tattaattgt agcatatttt
     1981 caacaagcct attatgaaat acacatgcag atgaacaaat accagttaca cttttaaact
     2041 ttatgaataa aacttcgcaa gaagatgttg tggttactgt aacattactt ttatgtagtc
     2101 tagtacatgc gaatacctct ccaaataaat ctccaggcaa gagttcagct acaatattcc
     2161 tattcccttc gatatcttcc tttattatat gagcacttcc tttaagcata attccaatag
     2221 aagtaacttc acttccaaca gagaatatta tactatcttt tgtgtaagtc ttatctacaa
     2281 cacctaaaca ttccaacatt tcttcaagtt catcactttt aattccttca aatagaggaa
     2341 tttttttaag taggtctata tgcttttcta aaaatttttt caaataatca cttccttgtt
     2401 gcatatgcaa ccgataattt gttttcattg tactatacta agtttataaa agcaagggga
     2461 tataaaaatc ctactacaag aaatttgaaa taaagaaata taggtattaa aaatatatat
     2521 ataagaaatc aatactttaa attaaaaaaa ttttatgagg tgatataaat gatgagaaaa
     2581 ataattaaaa ttgatgagga aaagtgtaat ggttgtggac tatgtgttga agcttgtcat
     2641 gaagaagcta taggaatggt aaatggaaaa gcaaaacttt taagagatga ctattgtgat
     2701 gggctgggag attgtctgcc aacttgtcca acaaatgcga tttcatttga gtatagagaa
     2761 gcagcagaat atgatgaagc tgcagtaaaa gcaaatatgg aagcaaagaa agcacaaaag
     2821 aaaactttag catgtggatg tccaggttct cagtctaagt caataaatag agaggtttca
     2881 aatagtatgt ctataagcaa tgatatagta gagataaaag gttctcaact taatcaatgg
     2941 ccagtacaaa taaaattagt accaactaat gcatcatatt taaagaatgc aagtctttta
     3001 atagcagcag actgtacagc gtatgcatat ggaaattttc ataataaatt tatgaaaaat
     3061 aaggttacat taatcggatg ccctaaactt gatgaagttg actatgctga aaaacttaca
     3121 gagattttaa aagaaaatga tattaaaaat atagtagtaa cacgtatgga agttccttgc
     3181 tgtggtggta tagtaaatgc tgttaagaca gctctacaaa atagtggaaa aatgatacca
     3241 tggcaaatag ttactatatc tgtagatgga aaaattgtag atggagaaat ttaattaagt
     3301 gaattataga aaaatataat aaattttaat aaataaaaag ggaggaataa aaaatggaaa
     3361 aaatgttttg ttttcaatgt gaacaaacag caggaggtaa aggttgtact ataaatggtg
     3421 tctgtggtaa aaaggggggt acagctaact tacaagacga acttacagga gtgttgattg
     3481 gtctttcaag agcaactatt ggaaataaga atagaccaac aagtgaaaca gataaaatta
     3541 tgatagaggg gctattcact actataacga atgtaagttt tgatgatgaa gctataaaaa
     3601 gacaaattga aaaaactgag gtagaaaaaa gtaagcttgt acctagatgt tcagattgtt
     3661 caacaacttg taatagaaat gataactatg atatgaagga tttatggaat gataatgagg
     3721 acatacgttc attaaaatca ttaatcttat ttggattaag aggtatggct gcctatgcat
     3781 atcatgcaat ggtacttggt tatacagaca aagacgtaaa tgaatttttc tatgaaggat
     3841 taatagcagt tggaggagac ttgtctattg acgaactttt aggtctagtt atgaaaactg
     3901 gagaaataaa cttaaaatgt atggaattgc ttgatagagc aaatactgaa acttatggaa
     3961 caccagaacc gactcaggta tctatgaaaa tcgagaaagg gccatttatt gtagttacag
     4021 gacatgacct ttatgattta cacaaattat tagaacaaac gaaagataag ggtataaata
     4081 tatatactca tggtgagtta ttaccagcac atgcatatcc aaaactaaaa gaatataaac
     4141 atctaaaagg taattttggt acagcatggc aaaaccagca aaaagaattt gataatattc
     4201 ctgctccaat attatttaca acaaactgtt taatgcctgt taaagatagt tatagagata
     4261 gagtatttac tacagaagta gttgcttatc caggtatggt tcatattgat gaagataaag
     4321 atttttctag tgtaatagaa aaagctcttg aacttggagg atatagagaa gatgttcata
     4381 tgactggtat taatggagga gatacattaa ctactggttt tgcaagaggt acagtttcat
     4441 ctgtacaaga taaagtagta gatgctgtaa agagtggagc tataagacac tttttattgg
     4501 ttggaggttg tgatggtgca aaacctggaa gaaattatta cactgaattt gtaaaacaag
     4561 ctcctaaaga cactgttata ttgacacttg catgtggaaa atatagattt aatgatttag
     4621 accttgggga tatatgtggc ttacctcgtt taatggatat gggacaatgt aatgatgctt
     4681 atagtgcaat taaagtggca gtttcattgg caaatgcttt tgaatgtgga gtaaatgatt
     4741 tgcctcttag catggtactg tcatggtatg agcagaaagc tgtttgtata cttcttacac
     4801 tacttcattt aggtatcaaa aatatctata tagggccttc tttgccagca ttcttatcta
     4861 agaatgtatt agatatattg gttgataaat ttgcattgac acctatatct actcctgaag
     4921 aagatatgaa gaagatttta ggataaataa acatatctat acttaaagat atttatagtt
     4981 aaaatatttt taagtatgcc acaattaaga taaggggtta aacttaaaat ttgattaaaa
     5041 aatcaatttt gagatgaccc tttatttatt ttttgtaata attgaaaaat aaacctgctt
     5101 tcagtatatt ctttttaaga atctttgtat taaatttata atacttagat atataatatc
     5161 ttatatattt tattttaagt attaaaggtt tgaatgtaac ttaaatatta aaagaggaac
     5221 attgtaatat gtaacttgca taaaatatat atactatagt gaaattattt tgattaaaat
     5281 ttaaaatata aggtgtttta tgtgggggta tatgtatatg aaaaattcta attttaatat
     5341 attggcattt gatggtggtg gattaaaagg ggcattgagt atatccatac ttgagaggat
     5401 agtaaaagag tatccaaatc tattaaacaa tataaatatg tttggaggta catctacagg
     5461 gagtctaatt gcactagggc ttgcgtatgg tgtaagccct aaagagataa aagaacttta
     5521 ctcaattgaa aattcaaagt atatttttaa taaaagttat gcagaaatac tcagaccaaa
     5581 gtatgaaaac aaaaacttaa aagaagtttt attaagtata tttccagagg aactagaatt
     5641 aaaagattta aataaattag taatgatacc aagtttttat ataggaaatg aggaaaatgc
     5701 atggaaacca gtgttttata acaatatgcc aaattctttt acaaagacta gcaaagttgt
     5761 agatgtagca atggcaagta gtgctgctcc ggtatttttt ccaacatata atcgtcatgt
     5821 tgatggagga ataatagcaa ctgacccgag tttagcgtgt ataattcatg ccattgacag
     5881 tggatttaaa cttaagaata caagactttt ttcaataggg actggatatg tatataacag
     5941 tataaaggca gatactactg aatggggagc tattgactgg ataattaata aagaacccga
     6001 tttaccaatt atatctatta ccttagaagg aaattctcaa atgagtcagt tattttctca
     6061 aaaacttctt ggagataatt actatagatt aaatcctaag atggaaaaag atgtagctat
     6121 ggatgattgt gatgcattag aatatctaat gtctttagga gaaaattgtg atataaaaga
     6181 tgcttttgga tggataaaga aaaagagctt ttatagaaat tagattcaat ttgcaattgt
     6241 atttttacac atgatttcat tgagtaggta aaaataataa aatgcagatt attaagttac
     6301 ttcttaggga ataaataaag tataatttat ttaaggagtg atgaaaatga taaaacttgc
     6361 tacttttgca ggtggatgtt tttggtgtat ggtaaaacct tttgataagt atgatggagt
     6421 tattaaagta gtttctggat atacaggtgg tcatgttgaa aaccctacat atcaagaggt
     6481 atgctcagga actactggtc atttagaagc aattcaaata acatatgatg atgatataat
     6541 aagttatgat gaacttctaa atatcttctg gaaacagatt aatcctacag atgatggtgg
     6601 acaatttggt gataggggaa ctcaatataa gactgctata ttttatcatg atgaagaaca
     6661 aaaaaatata gctttagagt caagagaaca tctggaaaat agtaaaatat ttgatagtaa
     6721 aatagtgact gatataattc cagcaactaa attctacgaa gcagaagaaa atcatcagga
     6781 ttattataag aaaagaccat taaactacaa tatgtattat aaagggtctg gaagatataa
     6841 ttttgtaaaa agccattggg atggaaacaa tataaatagg gaagagttaa aaaagacttt
     6901 aactcatata caatttgaag tcactcaaaa tgatatgaca gaagtacctt ttgaaaatga
     6961 atattatgac aataacaaag agggaattta tgttgatatt gtaagtggag aagtgttatt
     7021 ttcttcaaaa gataaatttg attctggatg tgggtggcca agtttttcaa agccagttat
     7081 agataaatct atcattgaga gaagtgattt ctcacaaggt atgtacagag ttgaagtaag
     7141 aagtgctaaa ggaaattctc atttaggtca tgtatttgat gatggtccaa aagaacttgg
     7201 aggtttaaga tattgtataa attctgcttc tcttaaattt ataccaagag aaaatatgga
     7261 agctttagga tatggagaat atttaaaact ttttgagtaa ttaggaatat ttattataaa
     7321 cttatctaaa aggtgaaaat ataaaaaaat attttcacct tttgtttttt tgtcaataat
     7381 atgataaatt attaattgta atcttattta taccaataga ttaagaattt aattttgaaa
     7441 gagagaaaac aaatgaattt aaaagacttt aatggaaaga gattaaaatc agctagaatt
     7501 tttagagcaa agacgataga acagttgtct aaagaaacta aaataaataa aaaagattta
     7561 aaagcttttg aggaaaataa gtatgtacca aatatagaaa atacattaaa attatctaat
     7621 atattaaatt ttccaaaaga gtatttttat aaaaatgaaa atataaatat cgttgtagag
     7681 gatagccact ttaaccctca atctaaacta cctagagtag aagagatttc ttatagagaa
     7741 aaaataatta taatacataa aatatattca tttatggaga attatattaa gtttccaaaa
     7801 gaaaacttgc caaatagaaa agtaatgtca gatattaata taaatgatat agaatctctt
     7861 gcatataaga ctagagagtt ttgggattta aatagtactc caatagtaaa tatggtaagt
     7921 ttgttagagt ctaaagggat tataatatca ggtatgaatg tagatagaaa aggggcaact
     7981 atctttactc aaaaacagag aattagtaaa gaatctaaat atctaatatc tctgggtaat
     8041 gacaaaaagt cagcatcaat tagaaattat actttggcat gtgagcttgg atatataata
     8101 tcaagtgaat taagaatacc aagtaagcaa ttttcagaag atgagtatgc ctgtgcattt
     8161 ttattgccaa aagagagttt tttaaaagat ttgactcatc cagaagattt agattattat
     8221 gtagaactaa agaaaaaatg gattgtacct atatctgcta tgatttttag agcatataat
     8281 ctagaaaaga taaattacaa aaaatacaat tatcttatga atgaaatgga taaaaaaggc
     8341 tggttgatag aagaaccact agacaaaatg aaaggttcaa gcccaacgta tttaaaaaga
     8401 gcagttgaat tattgataga aaataaaata atgagtgtaa atagtatagt atcaagttta
     8461 gaggaatttg gaataaatct ttatccagaa gacttagaat tattgatggg attgaaaaaa
     8521 ggattgttat ctcaagaggt aaataaaaaa agtaaagtta taaaatttga tggtaaaaaa
     8581 taggtttata ttttagtatt aaaattaaaa gcaggtacaa atgatttaaa cattaactta
     8641 gttaaaagtc ttttcaataa gtcatttacc tgcttttagt gtaagaaaga atattgaatc
     8701 taaagtgttt ttgaaagtgc aatatattcc cttaaaacag aacaagattt attaaattcg
     8761 ttttgctcat attcagtcat attgatttca ataatttctt caataccatc ttttcctata
     8821 acacatggaa cacctgcaaa tacatttctt tcgttatatt gaccttctag taatgtagaa
     8881 actggaagaa cttttttctc attgtgtagt atagctttta caatttctac taaagcagta
     8941 cctataccaa attctgtaca atctttacca tttattatac ttattcctgt ttttttattt
     9001 ttttcaacta ttgatggtaa gtctaaattg ctataagtac ttgggttgtc ttttatcatg
     9061 tctaagattg gtttaccacc aattgaaaca tgagaccaag gaaccatttg agaatctcca
     9121 tgttcaccca tagaataagc ttgaattgat tgttgagcga ttccagtttc ttcagataaa
     9181 atccttctaa gtcttgttga atctaaagct gttccagttc caatgacttt gtttttagga
     9241 aagccagatt tttcccaaat ataatttgta actacatcaa caggattaga tatgactaca
     9301 aatataccat caaagccaga atcaactatg ggttttacta tagattttat cattccaata
     9361 gttggtctta gtaaatctaa tctagttgtg ttttgtctac gtaaaggccc ttctgaagag
     9421 tctgcaacac ttatcactac tatgtcagaa tctttacagt cagaaaaagt tcctttttct
     9481 atatgtactt tatgtggcag atatgaaact gcatcagcta aatctaaagc ttgagctttt
     9541 gatttagatt catctatatc aatcataaag agttcatcac aaactccttg agttattaaa
     9601 ctaaatccac aatgagaacc aacatgccct gaacctacaa tagatatttt tcttggcttt
     9661 attgccattt taaatcactc cccctaaaat aacgatacat tgaaaattat agatgttatt
     9721 aaaagctgtt tttggatatt ttaatattct attatttcag aaaatttatt taatatgatt
     9781 ttatactaaa atttttaaaa aagcaatgtt aatatactct ctattagtga atattaaagt
     9841 attatatgta tattaataat tattaaaata tgtaatgtca ctgatagtta gaatatttaa
     9901 gtgctaaaag atgtgtataa ataataatga tgtcagttta taatgatatt aaattgagat
     9961 atactgtttc tctaaattaa aaaataaagg agtaaatgtg ttatgaatta tcatacaaaa
    10021 gaagaattgg tggaagcact gagagtagta tcttcaagta ttattaattg tggaaaagga
    10081 cagaagaaat tttctgagga gacatctcat catacacgtt ttaagaatat tatagaagta
    10141 atgtatattt caaaatcatt aataatggat gaaattagta aaagagattg aagcttattt
    10201 tgcaatttaa catgttttaa tatacatttt attatataag aaaataagta aacatacatg
    10261 ttataaaata ttggaataat atacaattat aaatttgtta acactaatat ctatatgtta
    10321 aaatatagta gaagatgtta gtaaataata ggatgagttc tattttaata caattaaatt
    10381 aagcttagtt tgaaatttgt atctaaaaag taaagtaatc tagaattaag aaaatggaga
    10441 tagaattata atggaaaagt tatattatac aaatcagtat ataagagatt ttacagcaga
    10501 aataattgaa ataaaagaag tagaaaataa gtatcatgtt ttattagata agacagcttt
    10561 ttttcctggt ggaggaggtc agtttggaga cctgggaaaa atagagagtg atgatgtaat
    10621 aaatgtgtat gaagatggaa aaaaaatata ccatgtatta gataaaaaac ctataaagat
    10681 acataaggta aagtgtagta ttgattggga tagaagagaa gatggaatgc atcaacattt
    10741 tggacaacat gtattgtctg gatgtttttt taaaactttt aatgcaaata cgacaggttt
    10801 tcatttggga aatgagtata gtacagtaga tatagaaggt aatttagaag aggataaaat
    10861 tagagagata gagttgtttg ccaatgaaat tattcgtcaa aatatacaag tagagacatt
    10921 acttccaacg aaaaaagaac taaaaaagat ttggttaaga cgtgatttgc caaatactga
    10981 tgaagagata agagtaataa aaataggtga tttagatacg aatgcatgtt gtggagtgca
    11041 tccaaaatca actggtgaat tgagaatgat aaaaataaag aaatgggaaa aacataagtc
    11101 aagtacaaga atagagtttc tagcaggtaa aagggcagtg gatgaagtat tgaagaggga
    11161 tatatatttg actaaaatat gtagatattt aagctgtagt gaggaagatg ctataaatgg
    11221 tattgtaaat ctaaatagta aagtggaaga ggctttaatt aaaaaaagaa ggcttgaaga
    11281 agtagtatct acatatcagg tcaaagaaat gattgaaaaa gcaaataagg ttggcaatat
    11341 ttcggtcatt aaaaaaattt atgatgatga agatttgaaa tatgtaaata agatagcaaa
    11401 taaaattgca gaatatgaaa atagtattgc attattagct gttaaattta atgataaaat
    11461 aaatttagtt tttgcatgtt ctaaaaattt aaaagatatt aatatgggag ttttattaaa
    11521 ggatgcaata agtcttatag atggcaaggg tggtggaagt aaagtattag ctcaaggagg
    11581 aggtaagaat aatggaaatt tagaggctac acttgattat gcatttatga agatagaaaa
    11641 aactctataa atatattata taaaaaacct tagtagataa aatagatatg gaggaataag
    11701 tatggagcaa caaaaggact acatagagtt atatgaaaat gaagaactaa tagagataag
    11761 agaagcacgt atggatgatt tggatacaat agcaaaattt aattataatt tggctaaaga
    11821 aactgaagga aaagaacttg atatggatgt tttaactaaa ggtgtaaaag cattgttatt
    11881 agatgagaga aaaggaaaat atcatgtata tacagtattt gataaagttg ttgcacagat
    11941 tatgtataca tatgagtgga gtgattggag aaatggaaat ttcctttgga ttcagagtgt
    12001 atatgtagat aaggaatata gaagaaaagg tatctttaat tatttattta attatataaa
    12061 aaatatatgt gataaagatg aaaatatagt tggaatgaga ttatatgtag aaaaagaaaa
    12121 cataaatgca aaagcaacat atgagtcttt aaatatgtat gagtgtgatt ataatatgta
    12181 tgaatacgaa gtaatacatt cgtaatataa atttgtaata ctgttatact gatgttataa
    12241 agtattgatt atattgacga ttatatgaaa taaactggat attataatta gaatttttag
    12301 ggggtataaa aatgggcgtt ttaaaaggaa tgttttatgt atttttattt ttagacttag
    12361 tgtcaatatt ctgtttcttt ttcaataaag gaaaaatagc atctaataaa attgtgttta
    12421 atgcaatagg agtacttaca tttgtacttt gttttatgct ttttagttat tatcctaata
    12481 ataatcttat tggaaaattt attgcttctc tattttttat atttggagtt gcaggagtta
    12541 tgttgaaaga aaaaaatttt ttatatgcta gacttctttt aactgtagtt atagtttttt
    12601 ctacattaag attgttcgtt attcaataaa atgtatttgt atgaaaattt attaaagtct
    12661 acacatttaa gtgtaggctt ttttgatttt ttgtttgaaa attaaggaaa ttttaaggaa
    12721 attttaaaat cgtcttaaat atttattgat atacttaaaa tattaatagc gaaaggagac
    12781 ttatcagtga tagaaagtaa aaagtcagaa aaattgttac tgtcaattat atacataata
    12841 tttttggtat atattttaat gattataaga ataattttat ttagagatgt accaatttac
    12901 gctattttca agggaacgtt taggaatgta aatttaattc cattttatac aatatatcaa
    12961 tttatagtag atagtaatct tgactttatg aaagctactg taaatattat agaaaatata
    13021 ggtatattta ttcctatggg aattttttta cctatagtat gtaaaaatct aaataaaaaa
    13081 actataatta tagtaattat acttgttagc ctagcatttg aattaacaca atatattttt
    13141 gctcttggaa gtagtgatat agatgatgtt attttaaatt cattaggtgg cataattgga
    13201 attaatattt acataaacat gaataaatta tttcccaatg atattaacag atttaaggct
    13261 ataataggta ctagtttagt tttaggagtt ataggattag gagttatttc taaaaattat
    13321 cataacttac taacttttaa atttagacct gatagaaaaa tatcaaaaat attaattgaa
    13381 gaaaataggg aaataattaa agatataaat aaagatacag tagatatagt tgggacattt
    13441 gagagcttta aaaaaggaat aataactatt aaagcaggtt ctaataacaa agtaaagaga
    13501 ccagagaatt taattgattc tgatggaaat ataagaattt atttaaatga aaatacaaaa
    13561 ttagtatctt atataattac caaagaatca aaaatggata tagttaaata tgaggaattt
    13621 gatgtgaaga atttagattt attaaggaga tatgatacta ttaatgtttg gattgataaa
    13681 gaaaatcagc caaaggataa acatggtatt atggctagta aattattaat tggattgtat
    13741 gaataaaata ttaaacaaga ataaaagaat aacaaatata aaaaacgaaa aaactatttc
    13801 tataattatt tttacgttgt gcataaaata agaacattag tgaaggagta gagataaatt
    13861 atggagataa taaaatatat cttgtacttt tttatatatt catttttagg atggacagta
    13921 gaaagtatag gatgttctat agcaagcaaa agaataatca acagaggttt tttaaatggt
    13981 ccaatatgcc ctgtttatgg ttttggagcg gtaattgtga tatcactatt gggaagattt
    14041 aataatgtag taatagtatt tctattagga atgattttaa ctacgatact agaatatttt
    14101 acaggattta ttttagaaac cttatttcat gctaaatggt gggattattc tgacaaaaaa
    14161 ttcaatataa agggtagagt atgtttaaaa aatgcaatat actttggtgt aatgtctgtt
    14221 ttaataataa gatttataca tccatttata aaatattttg taagtataat tccatataga
    14281 atattaattt caatggctat aattacaaca ctttggacta tacttgattt gattgttact
    14341 attataacac ttaaaaaatt agatataaag ttaaacttat tagacgatat aattacagac
    14401 cttaatgata taaatgtgaa attggataaa tttgatagag gagaaataca agctttattt
    14461 aaaacaataa ataacgacga attagaagtt agagaaaaaa taaacaaaat aaatagtaag
    14521 ttggaccgta tagagtctaa tattatttta caaaaaagag ttataaaagc ttttccacat
    14581 ataaaacata aaaaacaaca agagcaacta gaacatttta aaaaaattat taatgagaaa
    14641 aggtaattat acaatttaat gaagacgaat agaataatgg tatttataag atgattttca
    14701 gaggactcta taaaaataga atagagtcct ttattttttg aaaaataatg tttatttgat
    14761 aaaaataaaa tatattgttt ctgaataaca aatattttga aaattataaa aacatatatt
    14821 gacaatttgt gtcaaaaata ctaacattaa gtatataaag aattttatat gagaatatct
    14881 ttataaatcg caataatttt aaaacataaa tttatttaaa gaggggatga tttgccaatg
    14941 agcgagataa ctagtcaaat gataagtaca gaagaaaaaa aatatgttgc taaaactcaa
    15001 aagatacctt attatccagt agcatttaaa tcaggtgatg gtgcaatgct atatgattat
    15061 gaaggtaatg aatatgtaga ttttttagca agtgcaggct ctgcaaatgt aggtcatggt
    15121 aataaggaaa tctcacaagc agttaaagaa caaatggatg atataacaca atatacactt
    15181 gcatatttcc atagtgatcc tcctgtaaaa ttagctgaga agcttgtgga aatagcccct
    15241 ggagataatg ataaaaaagt actatacagt gcaactggtt ctgcttgtat agatgctgct
    15301 ataaaattag caagagggta tactggaaga acaaagataa tatctatgtg tgaatcttat
    15361 catggaagta cttatggagc tatatctata tctgctttaa gtacaaatat gagaagaaaa
    15421 atgggtccat tgttaccaga agtttatcac ttccattatc ctgataaaaa tagaacagct
    15481 aaagaatgtt tagatgagat agaatatgct tttgcacact atctaccagc agaagaggta
    15541 gctgcaatat ttatagagcc aattgcagga gatgcaggaa taatagtgcc tccagtagag
    15601 tgggtacaag gtttaagtaa aatatgtaaa gaaaatggaa tattacttgt aagtgatgaa
    15661 atacaacaag gtatgggaag aacaggtaag tggtttggta tagaaaattt tggtgttgaa
    15721 gcagacctta tagttcttgg aaaatctgtt ggaggtggat tacctctagg agcagttgtt
    15781 ggaagaacag aaataatgca aagtcttgat gcaccagcac atttatttac tttagctgga
    15841 aacacaacag tatgtgtggc tgctttaaaa tctatagaga taattgaaaa agaaaactta
    15901 cttcaaaaga gtatagaaat gggagattat attaaagcag gatttgaaaa actaaaagaa
    15961 aaatacgata taattggaga aataagaggc ataggattat ctataggagt tgatatagtt
    16021 aaaggaaaag gttctaatga aaaacatcca gatgctacag ctaagatatg ttatagatgt
    16081 atacaaactg gattaataat gatattctta ggacaatcta ctttaagagt gcaaccacct
    16141 ctagtaataa ctaaggagca agtagataaa gcaatgaata tcatagattc tgcaatagat
    16201 gattatttaa atggtagaat tggtgatgaa gtatatgaag taactcaagg ttggtaaaat
    16261 aaatattaaa tgaaaatagg agttatctca attttagaaa attatttctg aaaagagata
    16321 actcttttaa gttacccaca aataagaaaa ttgtttgatt cattaaagac tatatttcgg
    16381 atgtcgtttt tgtgagtatc agagacagta ttacgagaat aattaccttt attcgtacta
    16441 tctgttaatt tagttataat taagatagct aaaagaataa gaattactgt gtataaagca
    16501 ataacatatg gttttctttt atatttgtat ttgttattga aaaaagaatg gccataatta
    16561 tttttattta ctttagatgt atttgtattc tttttcttgt tacctttctt tttatcatcc
    16621 ttttttctat ttttagggta aggaatgact ttgtgtgtat tatcaagttt gatattttta
    16681 tttttttgaa tattgttttc caggctagct tttttttctc caaattgaat agttttattg
    16741 gtattgttgt tatctttcaa tgttaatctc cctcccttaa actttccctt tagataatat
    16801 tactactaac ctatggaata tacaataaat aatatataag taataaaatt ttataggtat
    16861 aaatctcttt ctccacgctc taaggcagtc atattgttag atactatgtt tcttatatct
    16921 tctctttcta tcttacctat ttcttctgcg ataagttttt tacccataat tttaagttct
    16981 tcatctccat aatcgattaa aaattcattt aatgtagtaa gagcatttgg tgtacataca
    17041 ttatggattt gtcgactttt agctaagctc atgaatctat cgccagttct acctttacga
    17101 taacaagctg tacaataact aggtatatat ccatcagtaa tcagttcttt aagcacctca
    17161 acagggcttc tatggtctcc aacttcgaat tgttctgtat tgtcaccatc ttcatatgct
    17221 ttatatcctc caacacctgt tagagaacct gcactaattt gtgatacacc atattttagt
    17281 aactcatttc tcatttcagc agtttctcta gtggacatta tgattccagt aaaaggaaca
    17341 gctaatctag ttatagctac tatttttttg aacatatcgt cagaaactaa gtgaggaaaa
    17401 tcttctaagc tcataccttc agcttttttc aatctaggga aagatatagt atggaaacct
    17461 acaccaaatt tttcctctaa gtgttcgttg tgcatcataa gtcctagaac ttcaaattta
    17521 gggtcagata aaccaaataa aactcctgca ccaacatcat caacaccagc ttccatagct
    17581 ctatcaaaag ctgttaaatg gtaataatag tcatttttta tagattgacc atgcattttt
    17641 ataaatgttg gtttgtgata agtttcttgg aataatatat aagttcctat tcctttttct
    17701 tttagtaatt tatactcatc tacacttgta gctgctatgt taacgtttac ccttcttata
    17761 tttccgtttt cattatatgt tgaataaatt gcatctaagc aatctaagat gtaatttata
    17821 tcacaatttt tagggtcttc accagcttct agagcaagtc ttttatgacc cattttttct
    17881 aatattttaa cctcttccct tatctcttcc atggtaagtt tttttctttt aaatttgttg
    17941 catttactaa aaccgcaata aacacattca tttacacagt agtttgatac ataaagaggg
    18001 gcaaataaaa ccactctatt accatatatt tcatttttta tttgcccagc tatactaaat
    18061 aatctatcta gttgtttttt atcttctact tcaagaagtg tagctatatc tttataacta
    18121 agtttttccc ttctatcagc cttatcaagt accttttcaa tatcatcaga agttgaattt
    18181 tttgcatctt ctaataaaga attaataagt tcatggttta tgaacattta caaacgcctc
    18241 cattcaatat tatcaccgcg agaatagtca acttcaagtc ctaatgactt gatgttttct
    18301 tctaaacttt ggtgatattc acaagcttct tgaccagtaa aggctttgtt atcgtaaaga
    18361 gaatattgtt ttctaaattc ttgaggagaa aggtttggca taattacatt gcaaccagct
    18421 aaaagacctg catttctacc actagggttt atagatgcca aggctgttgt agcgggtaat
    18481 aaaacttttg gaagtagaag tcttgtaatt gaaagcataa gtaatgtctt ctctaaatct
    18541 ccatgtttat aatccttaaa aattgtatca tggtgtggaa tgaaaggtcc tattccaacc
    18601 atatgaggat ttaactcttt taggtataat aaatcacgaa caaggtcttc gttgttctga
    18661 aatggtgatt caaccataaa tccagcacct acctgataac caatttcttt aaggtttttt
    18721 aggcattctt ttctagttct aagctcaatg tttggcggat gtaatttttt ataatgactg
    18781 tctgtagcag tttcatgtct taaaagatat ctatctgcac cacataaaaa gtatttttta
    18841 tacgaatcat aactcttttc tcctagtgat agagttatgg cacaatcctc atatttattt
    18901 tttatacttg aaacaatttc acatatttta tcatcagtaa aatatgcatc ttcaccacct
    18961 tgcaaaacga atgttctgta tcctatttta taacctatat cacaacattc aagtatttca
    19021 tcaagtgaaa gcctgtatct tatgatattt ttattagaag attgtattcc acaatagtag
    19081 caattatttt tacaatagtt tgtaagctct ataagtcctc tcaagtagac tctatttcca
    19141 taatgtttat ttctcatgtc gctagcttgt ttataaagat agtttcttaa attttgttcg
    19201 aagttatatt cctcattgtc gatattttct attaaatata gtagttcatc aaaacttaat
    19261 gaattaatgc tgtaaagttt atctataaag tatttaatct tatttttagt catattcaaa
    19321 tatataatta ttaagtatag ttaaattttt aataattgaa aagttcaagt gatctttcca
    19381 aaataccttt tacatatgct attaagatac catagtttac aataggtaca ttgaaagatt
    19441 ttgccttttc tattctagat aacattccag ctctattcat catacaagct ccacagtgaa
    19501 ctacaagggc atatttattt atatcttcag tgaaggatac tccagaacta aattcaaaag
    19561 taatgttttt gccagttttc tttctaatca tattaggaat ttttactgtt ccaatatcat
    19621 cagtttgtct atgatgggta catccttcgg ccatcaagat tttatcacca tcttttaaat
    19681 tttctaaagc ataagcgcca ttaatcaatt ctttaaggtc tcccttttgt ctagcaaaca
    19741 atatagaaaa agatgtaaga ggaatatctt ttggtgtatc tttatctact tgtggaaata
    19801 cttgagagtc agtaataaca agttttggtt ttttgcctaa attagataga gtttctttta
    19861 aactatcttc ttttgtaact atagaaattg caccactatc caaaatatct cttataactt
    19921 gctgttgagg aagtataagt ctaccttttg gagctgcttt atctattgga acaactaaaa
    19981 caattaaatc atttggttca attaaatctg ataccaattt gaactcagtg ctatccttag
    20041 gcaaaacttt tattatttca ttttttaaat tttcaattcc aattttatct gttgatgaga
    20101 cagaaacaac tggacattta actttatttt tagttaagtt taaaatttct gattgattct
    20161 taatagtatc aattttgttg agaattagaa tatgagggat attcttatca ttaaactttt
    20221 caattagtga caaatcttct tgtgatatac caatctggca atccactact agtaaagcta
    20281 tgtctgtctt ttctaaaaca tctagtgatt tacctattct aagttcacca agttcaccaa
    20341 catcatcaag accagcagta tctataagaa cacaaggtcc tataggaagg atttccattg
    20401 gtctaaatac tgggtctgta gtagttccag caatatctga gactattgca gcactttgat
    20461 ttgttatagc atttattatg ctagatttac ctgcatttct tttaccaaag agacctatat
    20521 gtactcttac cgattgtgga gtagaattta gactcatttg tactcaccac cttaaacttc
    20581 tttttttgat atactagttt ttacagatac atgaggtatg ttgcccaatt taccagtcaa
    20641 actattaata gtatccattt cgccaacaac tgctatacat acgattgaga caccttcttc
    20701 ttcgcaagga atgcccattc ttcctttaat aataccttta aaacctgata caacctcatt
    20761 gaatttaaat tgacattctt ttggctcttc caaaatagca cttataactg caaccttttt
    20821 cataaatatc ctcctaactc agaaaatatg tcttaaacaa atccaaaatc aaaaaacttt
    20881 tctttgtaaa gaaaagtttc tacaaaagaa aagttattaa ttacacaagt ataatgtgct
    20941 atattaaact atttccttac agattagata actcttttct ggtagggtta gcttgtaaaa
    21001 atttaattta acaacaagta actgaagaaa atttttatac aatttatata aattataata
    21061 aaaattaact aaagaaaatt gaagttactt atataatagt agtaaattga aattaagtct
    21121 atagaaaaac caatttttgt ataaaaataa aaattaaagt taattatttg ttaagaattg
    21181 actttggtaa aatatataat taattattct ttaagcatat aatttataag taattttagt
    21241 gtattttcaa tagcttctat atgtgttctt tcataatggt gactattgtt tgttccagga
    21301 ccaacacatg ctatttgaac atcttctccc caacgaatag cttctgaagc atctgaacca
    21361 tagaaagtaa atacatcgac agcgtagtct aaattattgt cttctgcaac atcaacaagc
    21421 ttgtttctta aattaaaatc atataatgat aaattatctt ttgcaactat agttacacca
    21481 tgttcactag atgtttgact tggtccagta ggtgctatat ctattgctac aaattctttt
    21541 gttttttcag gtaaacattt agaaacacca tgtccaattt cttcataatt acttatataa
    21601 aagttagtag tatgcttagg tgttaaattg ttttctttaa aatatctaca tatttcaaga
    21661 accattgcta cagctgattt attatctata tatctagatt ttataaaacc agattctgta
    21721 gcctcaaatc tatggtctag gcatacaaaa tccccaacac ttattcctaa atctaataca
    21781 tcttgctttg taaatacttt ttcatcaagt ctaataatca ttgtttcttc atttctttca
    21841 gtggcagctt ttgtttgacc atatatatga gtagaagcat acttaaatac aacacttcct
    21901 ctgatttttt taccttttct agttataaca gtacagtttt ctccctctat agctgcccaa
    21961 catccaccac caactttatg gtatttaaga gtaccatcag atgatatttc ttttactata
    22021 gctccaagtg tatccatatg tgcagatatt gttatttgat ttgaatcatc ttcaccagga
    22081 agagtagcta taagtgcacc tttttttgta agaatagtgt caagacctaa attttcaaaa
    22141 tcttttttga tttctaaaac tgcattttca gtatatccag ctgggcttgg aatgtccaaa
    22201 tattttttca ttaaatttat agtattagtt aaatttaaat tcatattgtt tcctcctaaa
    22261 taaatatatt tatacaaatt ataacataaa tacaaatgtt ctgaaaacta aaattaaaag
    22321 aatagaatct aaacatattt aaaaaaaaa
//
LOCUS       DAMJVG010000062        22088 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.062, whole genome shotgun sequence.
ACCESSION   DAMJVG010000062 DAMJVG010000000
VERSION     DAMJVG010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22088)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22088)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22088
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.062"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            134..469
                     /locus_tag="PC512_002613"
     CDS             134..469
                     /locus_tag="PC512_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2442348.1"
                     /translation="MYNIDDMIYNCPVEALSNILGKKWVAIIIWKIQEDKKRFGELQR
                     AIPDCSKKMLVQQLDFLIEQGIIVNQKKLVNNVVESTYFLSESGLRLLPVMEKMIMWS
                     NKNLNCDKY"
     gene            606..1883
                     /locus_tag="PC512_002614"
     CDS             606..1883
                     /locus_tag="PC512_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HDF2442349.1"
                     /translation="MQNVNLFLVFIEGIVSFFSPCILPILPIYLSILSNSSVENLKEG
                     KTSFIGSSLFKNTIFFALGISTTFFILGSSVKVLSMFFNENKDLIMFIGGIIIIIMGL
                     FYMGIIKSSILNREKRFNVKFKEMKAITAFILGFTFSFGWTPCIGPILASVLVMVSSS
                     SNHLSANLLIAVYTIGFILPFIITAMFYSKLFKTIDKIKSNMEIIKKIGGIILIVSGI
                     LMMVNGFGSISKHFNTSQNSKIESKQEENKRENSTDKEENSDGNDSQKDSNNDNNDKG
                     SNDEDRIKSIDFTLTDQYGKTHKLSDYEGKVVFLNFWATWCPPCKEEMPYIEQLYKDY
                     NKNNDDVVILGVASPNLGREGSREHVVNFLKEQGYTFPVVLDEDGALAYQYGINAFPT
                     TFIIDKEGYVTQYIPGAMDKATMASFIENQRNK"
     gene            2004..3392
                     /locus_tag="PC512_002615"
     CDS             2004..3392
                     /locus_tag="PC512_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDF2442350.1"
                     /translation="MKKTFDAIIIGFGKGGKTLAGDLANRGLKVALIEKSNKMYGGTC
                     VNVACIPTKSLENSANSVKTKNINSWDEVQAEYEKAIDKKETLITKLREANYNKLNSN
                     ENVTIFTGMGTFIDEKTVQVKTENEIYELVADNIFINTGSRPFIPNIKGIENKNIVYD
                     SESLMNLRVLPKKMTIIGAGFIGLEFAGIYSSFGAEVTILNSNNGILPNEDVEDSEEI
                     IKLLAKRNVKIVNNANIKEIKEVSELAIVEYEVDGKSKELTSNMILVATGRKANTEGL
                     GLENAGIELNERGFIKVSETLKTNKEHIWAIGDINGGPQFTYISLDDYRIVINQLFGD
                     KTRTTNDRKNIPNSIFISPAFSRVGLNVKQAKEKGYEVLVAKMPVEAIPRAKQIGKAD
                     GFIKIVIDKKSNKILGASMICENSSEIIHLIQLAVDLEVEYTYLRDRVYAHPTMTEAL
                     NDILSPNMIKEV"
     gene            3596..4309
                     /locus_tag="PC512_002616"
     CDS             3596..4309
                     /locus_tag="PC512_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017208807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF434 domain-containing protein"
                     /protein_id="HDF2442351.1"
                     /translation="MNKISKRGFDDSDKRWFSSKELTRLIKAKEEIEWLLNRDYKIDP
                     VVTFVGDRYQFSIRQRDALKRAVCTDEKNIIRQSKRLSLDKIKEDTVNIDGFNLIISI
                     EVGLSGGTLVIGSDGNIRDLAGLRGTYKIIDKTEEALNLIGKFFNKYNAQNLKFYLDA
                     PVSNSGNLKYRILEHAKTWGIETEVELVKNADVVLEKLDRVVSSDAVIVDKCISYFNV
                     ARGIIEEYIKECNIINLNK"
     gene            4427..5296
                     /locus_tag="PC512_002617"
     CDS             4427..5296
                     /locus_tag="PC512_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HDF2442352.1"
                     /translation="MRGWICVKLTKLNIKKYRAPIYKYALANINLRSAKSTNSSIITV
                     IPQGAKMEVLDEEDDWIKVMYNSQEGYVYKELVSVSEYAWSNLNLREDKSTTSNIITV
                     IPEKSRVEVLQVDGDWSKVVYDDKIGYVFNYFLSIDGNKPNELDYKYFYTDMIKFVNE
                     NNIKSTSDYLIVTDLRNKYTYIFKKDNGGWGQLYKWQCTIGKPETPTITGIFYISGRK
                     PSFGTDEYSVKYATRIKGGYYYHSVLYDSTGSYIIDGRLGEALSHGCIRLSTENAKWI
                     YDNIPDTTTVIIH"
     gene            complement(5451..6596)
                     /locus_tag="PC512_002618"
     CDS             complement(5451..6596)
                     /locus_tag="PC512_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HDF2442353.1"
                     /translation="MSIYYVPPINLLGKGCLNEAKDSIKSLGTKKAFIVSDKFLVSNG
                     TVKKVTDILSQIDIDFVVYDEVKQNPTVTNVNKGLKILKSENCDFVITIGGGSPQDCG
                     KAISILATNGGDIRDYEGINKTSKKCLPIIAITTTAGTSAEVTINYVITDEDRHVKMI
                     MVDTNSLATMTVNDPELMISKPSNLTAATGMDALTHAIEAVVANGAYDVTDSTALYAI
                     KQIFKYLPRAVKNGNDIEAREQMCYACFLNGIAFSNAGLGNVHAMAHQLGGLYDLPHG
                     VCNAMLLPIVEEENAKSAPAKFRPIAEVIGMDVNNKSDKECVDFVIDKIKALSEEVGI
                     PKSLKDVGVDNPNFELLAENSMKDACAGANPVFFDKDKIIELFMKIS"
     gene            complement(6929..7705)
                     /locus_tag="PC512_002619"
     CDS             complement(6929..7705)
                     /locus_tag="PC512_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HDF2442354.1"
                     /translation="MTSDNHRPTARILDILEALAESENGYTLTEIADVINAPKSSIFP
                     IVHTLNARKYITIDKNTSKYSIGIRSYTLGSSFFEKRTIFNYIIDEMTNIVNSCSETC
                     QLGILDNNEVLYIGKVDSPEPIRLISYVGKKIPANCTGLGKALLCDFDKEKLISLYPD
                     GLKGFTEKSITDFDVLYDQLLEVQRTQIASECEESMEHLKCLAVPIRKNGCIRAAVSV
                     TLPLFRANDEKIELIKKLLLNAQKNIQSMMEERNEDIVIN"
     gene            8287..9261
                     /locus_tag="PC512_002620"
     CDS             8287..9261
                     /locus_tag="PC512_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate permease"
                     /protein_id="HDF2442355.1"
                     /translation="MIMDFIKKIPAGMMIVPMFIAAFINTFCPDIVQIGSFTTAVFSS
                     VGSATIIGVQLVCLGTQLQFREMPKVLKRGGILLGSKFAIGALIGILIGKLFGMDGVL
                     GLTTLAVISAVTNSNGSIYLSLMTSYGDETDCATMSLLTLNDGPFFTLIALGTSGLAN
                     VPLLSLLAAIVPILVGMIIGNFDKKMKEFLEPGCNLLVPFVGFALGSSINLASILKGG
                     LSGVLLGLISVFVGGIFIVFCDKFIGKRPGYAGWAVATTAGNAIAVPAAVALVDPSWQ
                     PYVATATTQVAAAVVVTAILVPLITSWWAKKYGCPKFPKQNEDGTITA"
     gene            9359..9664
                     /locus_tag="PC512_002621"
     CDS             9359..9664
                     /locus_tag="PC512_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HDF2442356.1"
                     /translation="MINAVIIDEKDNVAVAIEAIAKGSEISFKLKDKTVKTITALDDI
                     TIYHKLAIKDMAKGDKVTKYGEHIGEANQEIKSGQHVHIHNVRSVREDLDKQVMTNI"
     gene            9820..10980
                     /locus_tag="PC512_002622"
     CDS             9820..10980
                     /locus_tag="PC512_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HDF2442357.1"
                     /translation="MKFYGYKRPDGRVGIRNHILILPTSVCASDTTRIIASQVQGAVT
                     FNNQNGCSQVHSDQQLTMDVMAGYAANPNVYGVIVVSLGCENCQNDLVVDAIKERTNK
                     PIKTLVIQEEHGTLKTIEKAVRYAREMAQEASLLRKEEFPISELILGTECGGSDPTSG
                     LAANPLIGELSDKLVDLGATSILSETTEFIGAEHILARRAVNEEVKEKILHIVHRYEN
                     SLKLVGEEVREGNPSPGNIAGGLTSLEEKSLGCIHKGGHRQISEVYDYAKQIDKKGLV
                     IMDTPGNDASSVAGMVAGGAQIVVFSTGRGTPSGNPIAPVIKITGNKITFANMEDNMD
                     FDASPVIYGPQTMEELTDDLLNMVVDVANGKQSKAESLGYTEMAIARVCNYV"
     gene            11030..11932
                     /locus_tag="PC512_002623"
     CDS             11030..11932
                     /locus_tag="PC512_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HDF2442358.1"
                     /translation="MKFVSFTEGENECKRTGVFSKDELFIIDVNSLNLSRNFKDLNEL
                     IQNVSSEDIIKLKTIINESTFYNYDVFKRERCTVHVPIEKPIHDILCVGVNYKDHLEE
                     TQTHFDDSFEEPQKTVYFTKRVTKAIGPEDEIDGHFEINNQLDYEVELGVVIGKTGVN
                     IRKEEVEDYIFGYTVINDISARKLQKEHVQWFRGKGLDTFTSLGPCILHKSAVPFPIK
                     LKVCSRVNGEERQSSNTGLFISDVSDIVSELSKGMTLEAGDIIATGTPSGVGMGFSPP
                     RYMSSGDVVECEIESIGILKNYIK"
     gene            12012..12905
                     /locus_tag="PC512_002624"
     CDS             12012..12905
                     /locus_tag="PC512_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HDF2442359.1"
                     /translation="MKAEFLTPVVTIFDEEGNLDKEGNKKVYDHLIDGGVDGLVIMGS
                     TGEFFNMSMDMQKELIDLVTSHVNKRVKVFIGTSRMCINESIELSNYAHNSGADGVMI
                     ISPYYFSLDDDSIELFYSEIAKNTEAEIYLYNYPDRTGYDLSPELTLRLARKHKNIVG
                     YKDTVTLMGHTRDLINTMKIEFPEFKVYSGYDENFIHNLMSGGAGCIGGLSNLIPEVC
                     SKWAEAYNNRDMEKVIEIQKYINKAMDFYLITNPFIPAMKKAMNIRGLQISDYMTAPF
                     VKPNEKQVCEIKKLMNELNIC"
     regulatory      12958..13139
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            13367..14497
                     /locus_tag="PC512_002625"
     CDS             13367..14497
                     /locus_tag="PC512_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2442360.1"
                     /translation="MKFKSNVLKQFFLIAMVIFMVGGLIGCSKSDKENKQASTGKKLE
                     LKYASGFSVEDLEDGIKKVTDGDNRELILIPKKIKIPEKYKNANIVRTPVDNVLIAST
                     TQACSLRTIDELDSIKAVTTEEQYWTIKEIKDLMKDGKIHYVGSNLAPDYEKIVDLNP
                     DLTIVSSGLSEADTKFIDKLKELGLNYVVDNEYKEQNPFGRMEWTSLIAAFYDKEDMA
                     TSELNKTVQKVEEVSKKIKNKAKPKVVWASVYEGSAYIAPKDSYVDNMIKMAGGINAC
                     ASIDSNEGRVSIEQLHEVAKDADIFVYSSSSDYAPNLDSIKSSAPVLADLDVVKNGNL
                     WVFAPDYYQSVDKTDELIVDLVEMFHPGTTGEKIKHYINYDK"
     gene            14569..15594
                     /locus_tag="PC512_002626"
     CDS             14569..15594
                     /locus_tag="PC512_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HDF2442361.1"
                     /translation="MDFINKMRIRNTTIFIVLIISMILTFLVCVAFGSVKIEFKEVID
                     VVLRGMDNTEHYKIIYNIRIPRVLATMVGGACLAVSGILLQIFFKNPIVEPYILGVSS
                     GSTLSVALMILGGYTLGFESVNSMSIFVAAFIGALIVMSIVILFANKVKNITTLLIIG
                     IMTGYVCSGITNVLQSFANSDKLKEFTMWSMGSFSGFTWEKVEILIIVGILGLLMTVF
                     IIKPLNAFLLGEEYAKSIGINIRFFRVLIVFISSILAAIVSAFAGPIGFIGLAVPQIS
                     KMIFKTSDNRVLIPVVIFLGSIVTALCDLISRVILSPVELPISTITSLLGAPIVVMLL
                     VKRKDRA"
     gene            15597..16793
                     /locus_tag="PC512_002627"
     CDS             15597..16793
                     /locus_tag="PC512_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2442362.1"
                     /translation="MLKTNNLSVGYNNKVVISNINVEVKNGEILCLLGSNGAGKTTLL
                     RSLSKLISPIKGEIYLNGVNINCISRKALSKKMALVLTNRLLGDLMTVQDIVNIGRYP
                     YTGFFGSLSKKDLIMVDEALESVDALHLKKRYFDELSDGEKQKVLVARALVQEPEIII
                     LDEPTTHLDIKHRLELINILKKLSKEKSISVILSLHEIDIALKSCDKVALIKNNKVIA
                     YGQPEDVVDEDIINSLYELDDKNFNSLLGSVEISNKSKNEVFIIGGGGKATPIYRAFT
                     KKGIGLYSGIIHENDIDYEIGRTMGIKMFTENPFEPISDESFNLAIRNLNDSKIIIDT
                     GFSVGETNKRNIDIIKEALKLDKKVYSFRNRDESKKYYDSLDSKIEHIDKVSQIINSA
                     DINNLL"
     gene            complement(16921..17646)
                     /locus_tag="PC512_002628"
     CDS             complement(16921..17646)
                     /locus_tag="PC512_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HDF2442363.1"
                     /translation="MKTISKQELEKTLEKHYLWLKNNNAGEKADLKELRLENMDLRGY
                     CLSNIDFSWSDLINLNLEKADLENSIFNNSYLSDCSLKNSILKNADLSGASFRFCDLS
                     NSDIRGANLENSNLEHATLNGVISDESTRFFKLYCPETGAFIGYKKCFNFRMVQLLIP
                     SDAKRVSATSNACRCDKAKVLSITSIDGKESFKSARAYADENFIYRVGETIVAEDFNE
                     NRWKESTTGIHFFLTREEAIGYL"
     gene            18124..20223
                     /gene="nrdE"
                     /locus_tag="PC512_002629"
     CDS             18124..20223
                     /gene="nrdE"
                     /locus_tag="PC512_002629"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HDF2442364.1"
                     /translation="MNWIELNNQVIIKNEQGKYQLEKDKEALSSYIEEFIQPKLRKFN
                     NLEERLKYLIDEGYYSKEVINQYSIDVIKNIYDMIDKHKFEFQSYMSANKFYQNYALK
                     SNDGKEILETYNDKVLIVALTLGNGDKDLALNLADKIVKQEFQPATPTFLNAGRKRAG
                     EMVSCFLLSVEDSTEGISYAISSSNHLSKIGGGVALNLSKLRASGESIKDIEGAAGGV
                     VGVAKMLEQSFSYFNQMGARQGSGAVYLTVFHPDFELLMDTKKINADEKIRLATLSLG
                     AIIPDKFMELAEKNEVAYAFYPHTVYKKYGVSLDEIEMDEWYDKLVNDSDIRKKEINP
                     RQMLTKIAQMQQESGYPYVVYIDTANREHTLKDVGIIKMSNLCCEIFQYQTPSEIEGY
                     GGKNEWGQDISCNLGSLNIANVMDNKTIESTVETAIRALSFVADSTDIKPVPTVSNSN
                     SKSHSIGLGAMNLHGYLVRENILYTSDDAIDFSNVFFAMVRYYSIKASMKIAIERNQT
                     FEGFDKSEYVKGRNSKVLSKYYEQSYLPKSEKVRALFEGIYIPTKEDWTKLLDEVKEK
                     GIYNAYLMAVAPTQSISYVQNATSSIMPITEPVEVRTYGDSTTIYPMPFLTNDNMLYY
                     QSAYRMDMRKVIDLVATVQNHVDQGISTTLFVTDEKTTRDIARHYIYAYKKGLKSLYY
                     TRTKMTRDTHECLVCSV"
     gene            20235..21206
                     /gene="nrdF"
                     /locus_tag="PC512_002630"
     CDS             20235..21206
                     /gene="nrdF"
                     /locus_tag="PC512_002630"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HDF2442365.1"
                     /translation="MTFNLHKIHNAVNWNREEDGFTQAFWEQNVKQFWLPEEISVSKD
                     IKVWNELSNKEKELYKKVLGGLTLLDTKQGNNGIPSMMSLTENLQRKAVLSFMGTMEE
                     IHAKSYSSIFMTLLSNLEIDELFEWIETEPTLQRKADLVLAQYENTTNQEGLYLSMVT
                     SVFLESFLFYSGFFYPLYLSGQGKMVASGEIISLILRDESLHGKYIGLLAQEIYDSFD
                     KMDKEMLEEKMYSILYSLMENEIEYTNVIYRESGLEKEVVNFLKYNANRALENLGFEK
                     LYTVDAINPIVLNGLSTETKTHDFFSTKGNGYQKGVYEELEDEDFII"
     gene            21282..21908
                     /locus_tag="PC512_002631"
     CDS             21282..21908
                     /locus_tag="PC512_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HDF2442366.1"
                     /translation="MKYEWRKRDKELYLPKKNPVIVEIPEQKFIMLKGSGDPNSKEFT
                     EAIGVLYSLAYAIKTMPKKGIVPEGYFDYTVFPLEGIWDKGEKSKGLDVLIKEDLIYT
                     IMIRQPDFVTQDLLDKATDIVKKKKPHNLLEKVRFGSINEGLCVQMLHIGSYDNEPES
                     FDIMNEFCKKNKLIRKSYTHREIYISDARKVSPESLKTVLRFEVEREV"
BASE COUNT         8556 a         2435 c         3883 g         7214 t
ORIGIN      
        1 taaaatagtt tgtaatagga gtatatataa taaaaatttt aattaaataa agctaggtat
       61 atttataata ttaataaata tattgctata aaagtttgtt taataaatta aataaagaaa
      121 agaggagaat aaaatgtaca acatagatga tatgatatat aattgtccag tagaagcttt
      181 atcaaatatt ttaggtaaaa aatgggtggc tataattata tggaaaatac aagaagataa
      241 aaaacgattt ggagagctac aaagagctat accagactgt agtaagaaaa tgttagttca
      301 acaactagat tttttaattg aacaggggat tatagtcaac caaaaaaagt tggttaataa
      361 tgttgtagag tcaacatatt ttttaagtga atcaggatta cgattgcttc ctgtcatgga
      421 aaaaatgatt atgtggagca ataaaaattt aaattgtgat aaatactaaa atttactctg
      481 taagtaatga aaatttaatt aagctatgag tagaaaaatg tattaaaatt acataatttt
      541 ttagttagat tttaatttag aaatgggatt gtaatattgg aaataaaata aggaggaatt
      601 ttaatttgca aaatgtaaat ttatttttag tatttataga aggtatagta tcattctttt
      661 caccatgtat actgccaatt ttgcctattt atttgagtat attgtcaaat agtagtgtag
      721 aaaatttaaa agaaggaaag acgagtttta taggaagttc tttatttaaa aatactatat
      781 tttttgctct tggaatctca acaacattct ttatattggg ttcatcagta aaagtattga
      841 gtatgttttt taatgaaaat aaagatttaa taatgtttat tggtgggatt ataattatta
      901 tcatgggatt attttacatg ggaataatta aatcttcaat attgaataga gaaaaaagat
      961 ttaatgttaa gtttaaagaa atgaaagcaa taacagcttt tatattaggt tttacgttta
     1021 gttttggatg gacaccttgt attggtccaa tattggcatc tgtattagtc atggtttcaa
     1081 gttcaagtaa tcatcttagt gccaatcttt taatagcagt atatactatt ggttttattt
     1141 tgccattcat aattacagct atgttttaca gtaaactatt taaaactata gataagataa
     1201 aatctaacat ggaaattatt aaaaaaatag gtgggattat acttatagta tcaggaatat
     1261 taatgatggt aaatggattt ggaagtataa gcaaacactt taatacgtca caaaatagta
     1321 aaattgaaag caagcaagaa gaaaataagc gagaaaattc tactgataaa gaagaaaatt
     1381 ctgatggtaa tgatagtcaa aaagactcta ataatgacaa taatgataaa gggtctaatg
     1441 atgaagatag aataaagtct attgatttta ctttaacaga ccagtatggt aaaacacata
     1501 aattaagtga ttatgaaggc aaagttgtat tcttaaattt ctgggctaca tggtgtcctc
     1561 catgtaaaga agaaatgcct tatatagaac aactgtataa agactataat aaaaataatg
     1621 atgatgtagt aattttagga gtagcttcac ctaatttagg tagagaaggt tcaagggaac
     1681 atgtagttaa cttcttaaaa gaacaaggtt atacattccc tgttgtactt gatgaagatg
     1741 gagcattagc atatcaatat ggaattaatg cttttccaac tacatttata attgacaagg
     1801 aaggatatgt aactcagtat attccaggag ctatggataa ggcaactatg gcatcattta
     1861 ttgaaaatca gagaaataaa taaaagtatt taagtataag tttataaatc aatttaaggt
     1921 tacaaaaaag tgcctaattg taccacctaa ataatcttgt tatagtaaaa gtataaacaa
     1981 tacaagaaag ggttgaattt tatatgaaaa aaacatttga tgctataata ataggatttg
     2041 gaaaaggtgg aaaaacatta gcaggggatt tggcaaacag gggattaaaa gtagctttaa
     2101 tagaaaagtc aaacaagatg tatggtggaa catgtgtaaa tgtggcatgt ataccaacaa
     2161 aaagcttaga aaattcagca aacagcgtaa aaacaaagaa tataaattct tgggatgaag
     2221 tacaagctga atatgagaaa gctatagata aaaaagaaac tttaattaca aaactcagag
     2281 aagctaacta taataaatta aattcaaatg agaatgtaac tatattcaca ggaatgggaa
     2341 ctttcattga tgaaaaaaca gttcaagtca aaactgaaaa tgaaatttat gagttagtag
     2401 cagataatat atttattaat actggttcaa gaccatttat acctaatatt aagggaattg
     2461 aaaataagaa tatagtatat gatagtgagt ctcttatgaa tctaagagtt ttacctaaaa
     2521 aaatgacaat tataggagct ggatttatag gtttagaatt tgctggtatt tatagttcat
     2581 ttggagcaga agttacaata ttaaactcta ataatggcat tttaccaaat gaagatgttg
     2641 aggattcaga agaaataata aaattacttg caaagagaaa tgtaaaaatt gttaataatg
     2701 caaatataaa agagattaaa gaagtttctg aattagcaat agtagaatat gaagtagatg
     2761 gtaaatctaa agaattaaca agtaatatga tacttgtagc tacaggaaga aaagcaaaca
     2821 ctgaagggct agggctagaa aatgcaggta tagaattaaa tgaaagagga tttattaaag
     2881 tctcagaaac tcttaagact aataaagagc atatatgggc tataggagat ataaatggag
     2941 gtccacaatt tacttatatt tcattggatg attatcgcat agttattaat cagttatttg
     3001 gagataagac tagaacaact aatgatagaa agaatatccc aaattctata tttataagtc
     3061 cagcattttc aagagttggt cttaatgtta agcaagctaa agaaaaggga tatgaagtat
     3121 tagtggcaaa gatgccagta gaagcaattc caagagctaa acagattggc aaggcagatg
     3181 ggtttataaa aatagtgata gataaaaaat ccaataagat acttggagct agtatgatat
     3241 gtgaaaattc aagtgagatt atccatctta ttcaattagc tgtagattta gaagtagagt
     3301 atacatattt aagagaccgt gtttatgcac atccaactat gacagaagct cttaatgata
     3361 ttctatctcc taatatgata aaagaagtat aacataagtt taatatataa atctaaaatt
     3421 atcattataa gtagatttta gaaagaggct atctcaaaaa atagagataa gtctcttttt
     3481 tactgtttaa ataataaaaa tatattttaa tggtattaaa aattatctta aaaggtgaaa
     3541 taatctgtat ttaatgtagt acagttatat ctttaaagca aggtggtgaa atgatataaa
     3601 taagatatct aaaagagggt ttgatgatag tgataaaaga tggttttcaa gtaaagaatt
     3661 aacaagactt ataaaggcta aagaagaaat agaatggtta ttaaataggg attacaaaat
     3721 agacccagtc gttacttttg ttggtgatag atatcagttt tctataagac aaagagatgc
     3781 attaaaaagg gcagtctgta ctgatgaaaa aaatattata agacaatcaa agaggctttc
     3841 tctagataaa atcaaagaag ataccgtaaa tatagatggc tttaatttga taatatccat
     3901 agaggtagga ttatctggtg gtactctagt aataggaagt gatggcaata taagagattt
     3961 agcaggtctt aggggaacct ataagattat agataaaaca gaagaagctt tgaatctgat
     4021 aggtaaattt tttaataaat acaatgcaca gaatcttaaa ttttatttag atgctccagt
     4081 ttctaattca ggaaatttaa agtataggat attagagcat gccaaaactt ggggaattga
     4141 aactgaagta gaattagtaa aaaatgcaga tgttgtattg gaaaaattag atagagtagt
     4201 tagtagtgat gcagtcatag ttgacaagtg tataagttat tttaatgtgg ctagaggtat
     4261 aattgaagag tatattaaag aatgtaatat cataaattta aataaataga taaatatagg
     4321 tgagaatata taagtatatg tagcaatatt cttagtaata caagtaaagt ttgaaaatag
     4381 gagaacgaat acatatcgaa tttcataaaa tgttgtaaaa agacatatga gaggatggat
     4441 atgtgtgaaa ttaactaaac taaatattaa aaaatataga gcacctatat ataaatatgc
     4501 tttagcaaat ataaatttga ggtctgctaa atctaccaat tcaagtatca taacagtaat
     4561 acctcaggga gccaaaatgg aagtattgga tgaggaagat gactggatta aggtgatgta
     4621 caattctcaa gaaggatatg tgtataagga gttggtatca gtaagcgaat atgcttggag
     4681 taacttaaac ttaagagaag ataaatctac aacttccaat ataattacag taattcctga
     4741 aaaatctagg gttgaagtcc ttcaagtaga tggagattgg agtaaggttg tatatgatga
     4801 taaaatagga tatgttttta attatttttt atcaattgat gggaataaac caaatgaatt
     4861 agattataag tatttttata ctgacatgat taaatttgtt aacgaaaata atattaaaag
     4921 tactagcgat tatctaattg taacagacct tagaaataaa tatacttata tttttaagaa
     4981 agataatgga ggatggggac aactttacaa gtggcaatgt actataggca agcctgagac
     5041 tccaactata acaggtatat tttatataag tggaagaaaa ccttcttttg gaacggatga
     5101 gtattcagtt aagtatgcta ctagaattaa aggtggatat tactatcatt ctgtactata
     5161 tgattcaaca ggaagttata taatagatgg cagacttggt gaagctctta gtcatggatg
     5221 tataagatta agtacggaaa atgcaaagtg gatatatgat aatataccag atacaacaac
     5281 agttataatt cattaagaaa aattttgagt tttttattgg gataatgatt cttaaattaa
     5341 taggattata tattaacttc tcataaagag tactatttaa aaagtgtaat aagagagtgc
     5401 tattaacaaa acaaagatat tttgaggcac tctcttataa atatacataa ttaagatatt
     5461 ttcataaaca attctataat cttatcttta tcaaagaaaa caggattagc accagcacaa
     5521 gcatctttca tagagttttc tgcaagcaat tcaaaattag gattatcaac acctacatct
     5581 tttaaagatt ttgggattcc aacctcttca gaaagagctt ttatcttatc tattacaaag
     5641 tcaacacact ctttatctga tttattattt acatccattc caataacttc agctattggt
     5701 cggaatttgg caggggctga tttagcattt tcctcctcaa ctattggaag tagcatggca
     5761 ttacatactc catgaggtaa atcatataaa cctcctaatt gatgagccat agcatgtaca
     5821 tttccaagac ctgcattact aaaggcaatt ccatttaaaa aacaagcata acacatttgt
     5881 tctctagctt ctatgtcatt accattttta acagctcttg gaaggtattt aaatatctgc
     5941 tttatagcat ataaggcagt tgaatctgta acatcataag caccattagc tactacagct
     6001 tctatagcat gagttagtgc atccatacca gttgctgctg ttaaattaga tggtttgcta
     6061 atcattaatt ctgggtcatt tactgtcatt gtggctagtg aattggtatc aaccattatc
     6121 atctttacat gtctgtcttc atcagttata acatagttta ttgtaacttc agcagatgta
     6181 ccagcagtag tagttatagc tatgatagga agacattttt tagaagtttt gttgatacct
     6241 tcatagtctc taatatctcc tccattagtg gctaatatag agatagcttt accacagtct
     6301 tgtggagaac cacctcctat agttataacg aagtcgcaat tttctgattt taatatttta
     6361 agtcctttat tcacattagt tacagttgga ttttgtttaa cttcatcata aacaacaaag
     6421 tctatatcta tctgagataa aatatctgtt acttttttta cagtaccatt tgaaactaga
     6481 aatttatcac taacaataaa tgctttttta gttcctaatg atttaattga atctttagct
     6541 tcattaagac atcctttccc aagtaaattt attggtggta cataataaat gctcataact
     6601 aaaatctcct tttattttca ttgattttta tgtaaaaata tatatctaac aattttcact
     6661 aatttactca taatatatcg tatcttagat tgagataggg ttgctggttc ttatataaga
     6721 acttaattcg taattacgat tatgattaga atttaacata gtatttttat catgtcaata
     6781 aaaatataaa aaatattata aaaaaaacaa agttactgta gttaaatcag caactttgtt
     6841 tttatagtat aaatcaaata aatacattag tttaaaacaa aatttttaat tattatgttt
     6901 tgatatcttc catatacaga atattaatct aatttattac aatgtcttca ttacgttctt
     6961 ccatcattga ttgaatattt ttctgagcat ttaagagtaa tttttttatc agttctattt
     7021 tttcgtcatt agctctaaat aaaggcagtg ttacactaac agcagctctt atacatccat
     7081 tttttcttat tggtacggca agacatttta ggtgttccat tgattcctca cactctgaag
     7141 ctatttgtgt tctttgaact tcaagaagct ggtcgtataa aacatcaaaa tctgtaattg
     7201 atttttctgt aaaacctttt agaccatctg gatataagct tattagtttt tccttgtcaa
     7261 aatcacataa aagagctttt ccaagacctg tacaattagc aggtattttt tttccaacat
     7321 aagaaataag tctaatcggt tctggagaat ctacttttcc aatataaaga acttcattat
     7381 tgtcaagtat accaagctga caagtttcag aacaggaatt aactatatta gtcatttcgt
     7441 caattatata gttaaaaata gttctttttt caaaaaatga agaccctaat gtgtaagaac
     7501 gtatccctat agaatatttg gatgtgtttt tatcaatagt aatgtatttt ctagcattaa
     7561 gtgtatgaac tataggaaag atgctacttt ttggagcatt gataacatct gctatttctg
     7621 taagagtata tccattttcg gattctgcta atgcttctaa aatatctaat atcctagctg
     7681 ttgggcgatg attatctgaa gtcataaatt tccccctctt tttattaatt taaagtatta
     7741 gaatatgttg attttagcac actatacgat attttacaat gtagaaaata aatatgtaaa
     7801 tttatatata aataagctct tgatttagat acagatagat atttttttag actgtacatt
     7861 aaggaataac taatttccaa aatataccta aagaaagtaa gtgatattta gttatataat
     7921 ttaagtaaat atatgcaata gttattttta tatgtaaata tcaaaatatt atgaacttat
     7981 attttatcta ttttttacac tgtataaaaa ctttatagtt ttgaatacta tataatttta
     8041 aatacgctgt atttttgcat ataaggaagt catttgataa tatacaaggt attatcagaa
     8101 agtttgaaaa aattttgaca aaaatttatt ttttttattg actcataaat aggaaaatgc
     8161 tatcattaat tcaaagattc gtaattaaaa acttagttct taaatacgaa ccgaaacggc
     8221 cgttagaatt aaagctaaaa acttaataag agtaattaaa tatcatgttt taggaggatt
     8281 aactttatga taatggattt tattaaaaaa attcctgcag gtatgatgat agtgccaatg
     8341 tttatagcag ctttcattaa taccttttgc ccagatattg tacaaatagg ttcgtttacg
     8401 acagcagtat tttcaagtgt tgggtctgca actataattg gggttcaact ggtatgcttg
     8461 ggaactcagc ttcaatttag agaaatgcca aaagttttaa agagaggtgg tatacttctt
     8521 ggttctaaat ttgctatagg tgctttgata ggtatactta taggaaagct atttggaatg
     8581 gatggtgtcc ttggtctgac aacattggct gttataagtg cagttacaaa tagtaatggt
     8641 agtatatatc tttcattgat gacttcatat ggagatgaaa cagattgtgc aactatgagt
     8701 ttacttactt taaatgatgg accatttttt acattaatag ctcttgggac ttcaggtctt
     8761 gcaaatgtac cattgttgtc attattggct gcaatagtgc caatacttgt tggtatgata
     8821 ataggaaatt ttgacaaaaa aatgaaagag tttttagagc cagggtgtaa tttactcgta
     8881 ccttttgtag ggtttgcact tggtagtagc ataaatcttg caagtatact aaaaggaggt
     8941 ttatcaggag tattacttgg attaatatct gtatttgtag gaggtatatt tatagtattc
     9001 tgtgataaat ttataggaaa acgtccagga tatgcaggat gggctgtagc tacaactgct
     9061 ggaaatgcaa ttgctgtacc tgctgctgtt gcattagttg acccatcatg gcaaccatat
     9121 gttgcaacag ctacaacaca agtggcagcc gcagtagttg tcactgcaat attagtacct
     9181 cttataacta gttggtgggc taagaagtat ggatgtccta agttcccaaa acaaaatgag
     9241 gatggtacaa taacagctta atttatatta cagtgagttg ttggtaaaat aataaattct
     9301 ttaattagat tttaggatat taataaaatt atattattta taaaggagag caagaataat
     9361 gataaatgca gtgataattg atgaaaaaga taatgttgca gtagctattg aagcaatagc
     9421 taaaggtagt gaaattagtt ttaaattaaa agacaaaaca gtaaaaacga ttacagcact
     9481 agatgatata actatttatc ataaattggc tataaaagat atggccaaag gtgataaagt
     9541 tactaaatat ggtgaacata taggagaagc aaatcaggaa ataaaaagtg gccaacatgt
     9601 acatattcat aatgttagaa gtgttagaga ggatttggat aaacaagtta tgactaatat
     9661 ataaaataat atttatagag ttataaaagt tgtattcatt gcttttagtg tcaaatagtt
     9721 tttaaatagg tttttagctg tttgattagt gagtgtaata aaaattataa tatataaaaa
     9781 ttatagaaag tatatagact attttaggag gaaatcagta tgaaatttta tggatataaa
     9841 agaccagatg gaagagttgg tataagaaac cacatattaa tattgcctac gagtgtgtgt
     9901 gcatcagata caactagaat aatagcatca caagttcaag gggcagttac ctttaataat
     9961 cagaatggat gttcacaagt acattcagac caacaattaa ctatggatgt tatggctggt
    10021 tatgcagcaa atccaaatgt atatggtgta atagttgtat ctttgggatg cgaaaattgc
    10081 caaaatgatt tggtagttga tgcaataaaa gagagaacaa ataagccaat aaaaactctt
    10141 gtaatacaag aagaacatgg aactttaaaa actatagaaa aagctgttcg ttatgctaga
    10201 gaaatggcac aagaagcttc tttgcttaga aaagaagaat ttccaatatc tgaacttata
    10261 ctaggaactg aatgtggtgg gtctgaccca acaagtggat tagcagcaaa tccattaata
    10321 ggtgaattaa gtgataaact tgtcgattta ggagcaacat caattttaag tgaaactact
    10381 gaatttatag gtgcagagca tatactagct aggagagcag taaatgaaga agtaaaagaa
    10441 aaaatattac atatagtaca tagatatgaa aattcattaa aattggttgg agaagaagtt
    10501 agagaaggta atccatctcc tggaaatata gctggtggtt taacaagttt agaagaaaaa
    10561 tcacttggtt gtatacataa aggtggtcat agacaaataa gtgaagtata tgattatgcc
    10621 aaacaaattg ataagaaagg tcttgttata atggataccc ctggaaatga tgcttcatct
    10681 gttgctggta tggtagcagg aggagcacaa atagtggtat ttagtacagg aagaggaaca
    10741 ccatcaggaa atccaatagc accagtaata aaaataactg gaaataaaat aacttttgca
    10801 aatatggaag ataatatgga ttttgatgct agtccagtta tctatggtcc acaaacaatg
    10861 gaagaattaa cagatgattt gttaaatatg gttgtagatg tagcaaatgg aaaacaatca
    10921 aaagcagagt cccttggata tactgaaatg gcaatagcta gagtatgcaa ctatgtataa
    10981 tctttaagta agaaaataaa tacatagaat tttaataaag ggtgagatta tgaagtttgt
    11041 aagttttact gaaggagaaa atgaatgtaa aagaactgga gttttttcta aagatgaatt
    11101 atttattata gatgttaact ctttaaatct cagtagaaat tttaaggatt taaatgaatt
    11161 aattcaaaat gtatctagtg aagatattat taagttgaaa actattataa atgaaagtac
    11221 attctataat tatgatgttt ttaaaagaga gagatgtacg gtacatgttc ctatagaaaa
    11281 accaatacat gatatcttat gtgtgggagt gaactataaa gaccatcttg aagaaactca
    11341 aactcacttt gatgatagtt ttgaagaacc acaaaaaacg gtttatttta caaaacgtgt
    11401 gacaaaggca ataggtccag aagatgagat agatggtcat tttgagataa ataatcaact
    11461 agactatgaa gttgaacttg gagtagtaat aggtaaaaca ggtgttaata ttagaaaaga
    11521 agaggtagaa gattatatct ttggttacac tgttataaat gatatttctg ctagaaagtt
    11581 gcaaaaagaa catgttcaat ggtttagagg aaaaggatta gatacattta cctctttagg
    11641 tccatgtatt ttacataaaa gtgcagttcc ttttcctata aaacttaaag tatgtagtag
    11701 ggtaaatggt gaagaaagac aaagttctaa tacaggatta ttcatatcag acgtttcaga
    11761 catagtttca gaactttcaa aaggtatgac cttagaggct ggagacatta tagctactgg
    11821 aacaccttct ggagtaggga tgggattttc acctcctcga tatatgagta gtggagatgt
    11881 agttgaatgt gagattgaga gtattggaat tttaaaaaat tacattaagt aactgtttta
    11941 atataattaa tattaaagct aaatctgatg tattaatgaa catattaaaa taaattttag
    12001 gagtttaaat tatgaaagca gaatttttga caccagttgt tacaatattt gatgaagaag
    12061 gaaatttaga taaagaaggt aataaaaaag tgtatgacca tcttatagat ggaggtgtag
    12121 atggactagt cataatggga agtactggag agttctttaa tatgtctatg gatatgcaaa
    12181 aagaacttat agatttagta actagtcatg taaataagag agtaaaagtg tttataggta
    12241 caagtcgtat gtgtataaat gaatctatag aactttcaaa ctatgcacat aatagtggag
    12301 cagatggtgt tatgataata agcccttatt atttctctct tgatgatgat agtattgagt
    12361 tattttatag tgaaatagct aagaatacag aggctgaaat atatttgtac aattatccag
    12421 atagaactgg ttatgattta agtccagaac ttacattaag acttgcaaga aaacataaaa
    12481 acatagttgg atataaggat acagtaactt tgatgggaca taccagagat ttaataaata
    12541 ctatgaaaat agagttccca gaatttaagg tttatagtgg ttatgatgaa aactttatac
    12601 ataatctaat gtctggggga gcaggttgta taggggggtt atcaaattta attccagaag
    12661 tttgctccaa atgggctgaa gcttacaata atagagatat ggagaaggtt atagaaattc
    12721 aaaaatatat taataaagca atggattttt acttaataac caatccattt ataccagcaa
    12781 tgaaaaaagc tatgaatatc agagggttac aaataagtga ttatatgact gctccatttg
    12841 taaaaccaaa tgaaaaacaa gtatgtgaaa ttaaaaaatt gatgaatgaa ttaaatatat
    12901 gttaaatcaa ccttgcaaag aggtcaacaa taaattacaa ttatcttaat aaaaattaaa
    12961 ttaaaataat actagggtac tatattagtt taatagggaa agtgatgaaa attcactaca
    13021 gcccccgcta ctgtatacgg atacgaaatc aaaatccact gaaatttata aaaattttgg
    13081 gaagggtgat ggaggaaaag ccgtgagtca ggagacctgc ccagtattat ataagttcaa
    13141 tttagggtgg agattgtaat ttataataaa atgaagtatc aattcgtttt tgtaaagttg
    13201 atatatgaac ttctccttat taaattagga gaagtttttt attttattaa aaggttatac
    13261 ttattaaaga tgactttagg ataactttaa taagtatact ttaaaaagca tatattatta
    13321 aagtttttta gccactcata aaaaataaga tattggagtg aaagagatga aatttaaatc
    13381 aaatgtttta aagcagtttt ttttaattgc tatggtaatt tttatggtag gaggtcttat
    13441 agggtgtagt aaaagtgaca aagagaataa acaagctagt actggtaaga aattagaatt
    13501 aaaatatgct agtggattta gtgttgaaga tttagaagat ggaattaaaa aagtaactga
    13561 tggagataat cgagaactga ttttaatccc aaagaagatt aaaattcctg aaaaatataa
    13621 aaatgctaat atagttagaa cgcctgtgga caatgtatta atagcatcta caacacaggc
    13681 ttgttctctg agaacaatag atgaactaga tagtataaaa gccgtaacaa cagaagagca
    13741 gtactggact attaaagaaa ttaaagattt aatgaaagat ggaaaaatac attacgttgg
    13801 ttcaaattta gcaccagatt atgaaaaaat agtagactta aatcctgact taactatagt
    13861 gagtagtggt ttatcagagg ctgatacaaa atttattgac aaattaaaag aattagggct
    13921 taattatgtt gtagacaatg agtataaaga gcaaaatcca tttggaagaa tggagtggac
    13981 aagtttaata gctgcatttt atgataaaga agatatggct actagtgaac taaataaaac
    14041 tgtacaaaag gtagaagaag taagtaaaaa aataaaaaac aaagctaaac ctaaagttgt
    14101 atgggcatct gtatatgaag gaagtgctta tatagctcct aaagattcat atgtggataa
    14161 tatgataaaa atggctggtg gaataaatgc atgtgcttca atagattcaa atgaagggcg
    14221 agtaagtatt gaacaattgc atgaagttgc aaaagatgca gatatatttg tatactcatc
    14281 aagttcagat tatgcaccaa atttagattc tataaaatct agtgcacctg tattggctga
    14341 tttggatgtt gtaaaaaacg ggaacctatg ggtgtttgct ccagattatt atcaatcagt
    14401 agataagacg gacgaattaa tagtagattt agttgagatg ttccacccag gtactacagg
    14461 tgaaaaaatc aaacattata taaattatga taaatagtac agagaggaca caaaaagata
    14521 ggttttatag attttagtta atatagcttt gctaagagga gtatacaaat ggattttatc
    14581 aataaaatga gaataaggaa tacaacaata tttatagtat taattataag tatgatactt
    14641 acttttttag tgtgtgtagc atttggctct gtaaaaattg aatttaaaga agtaatagat
    14701 gttgtattaa gaggtatgga taatacagaa cattataaaa taatatacaa tataagaatc
    14761 cctagagtac ttgcaaccat ggtaggtgga gcatgcctag cagtatcagg tattttatta
    14821 cagatatttt ttaaaaaccc aatagttgaa ccgtatatat taggagtatc ttcaggttct
    14881 actttatcag tagctctcat gattttggga ggatacacat tgggatttga gagtgtaaat
    14941 tcaatgagta tatttgtagc agcttttata ggagctttaa ttgtaatgtc tatagtcatt
    15001 ttatttgcaa ataaggtaaa gaatataaca actcttttaa taataggaat tatgaccgga
    15061 tatgtatgta gtggtataac aaatgtgtta caatcatttg caaatagtga taaattaaaa
    15121 gaatttacta tgtggtctat gggaagtttt tctggattta catgggaaaa ggtagaaata
    15181 cttataatag ttggtatatt aggtcttttg atgactgtat tcataataaa acctttaaat
    15241 gcttttttac taggagaaga gtatgcaaaa agtattggca taaatataag attttttaga
    15301 gttttgatag tatttatatc tagtatatta gcagcaatag tatcagcatt tgcaggacct
    15361 atagggttta ttggacttgc agtgccacaa atttcaaaaa tgatatttaa aacatcagat
    15421 aatagagttt tgataccagt agtaatattt ttaggcagta tagttacagc tctttgtgat
    15481 ttaatatcaa gagtaatttt atcaccagta gaattaccaa taagtacgat aacatcttta
    15541 ttaggagctc caattgtagt aatgttattg gtgaaaagga aggatagggc ttagacatgt
    15601 tgaaaactaa taatttaagt gtaggataca ataacaaagt tgttataagt aatataaatg
    15661 tagaagtaaa aaatggagaa atactatgtc ttttgggaag taatggagct ggaaaaacta
    15721 ccctattaag gtccttatct aaacttatat caccaataaa aggtgaaata tatttgaatg
    15781 gtgtaaacat aaactgtata tcaagaaaag cattatcaaa aaaaatggct ttagtactta
    15841 caaatagatt attaggtgat ttaatgactg tacaagatat agtcaatata ggaaggtatc
    15901 catatacagg attttttggg agtctatcta agaaagattt aataatggta gatgaagcat
    15961 tggagtctgt agatgcctta catttaaaga aaagatattt tgatgaacta agtgatggag
    16021 aaaaacaaaa ggtgttggtt gcaagggctc ttgttcaaga accagaaata attatattag
    16081 atgagcctac aactcacttg gatataaaac atagattgga actcataaac atactgaaaa
    16141 aattaagtaa agaaaagtca atatcagtaa tactttcatt gcatgaaata gacatagcat
    16201 taaaaagttg tgataaagtt gctcttataa aaaataataa agtcatagct tatggtcagc
    16261 ctgaagatgt agtagatgag gatattataa attcgcttta tgaattggat gataaaaact
    16321 ttaatagtct tttaggttca gtagaaatta gtaataaatc taaaaatgaa gtttttataa
    16381 ttggtggtgg gggtaaagca acaccaattt atagagcttt tactaaaaaa ggtataggtc
    16441 tgtattctgg aataatacat gaaaatgata ttgattatga aattggtaga actatgggga
    16501 taaagatgtt tacagaaaat ccatttgagc ctataagtga tgagagtttc aatttggcta
    16561 ttagaaattt aaatgattcc aagattataa tagatacagg atttagtgta ggagagacaa
    16621 ataagaggaa tatagatatt ataaaagagg ctttaaaatt ggataaaaaa gtttattctt
    16681 ttagaaatag agatgagagt aagaagtatt atgacagttt ggatagtaag atagaacata
    16741 tagataaagt ttctcaaata atcaatagtg cagatataaa taatttatta taatttatga
    16801 aataaaatgt acttatgtgc tatagaaaaa agagtataga ttataatttt tttgaaatta
    16861 caatctatac tcttttgtta ttttgtttat gtatttatat atttataaaa ctttagcatt
    16921 ttatagataa ccaatagctt cctctctagt taaaaaaaag tgaatccctg tagtcgattc
    16981 tttccatcta ttttcattaa aatcttcagc tacaatcgtt tctcctactc tatatataaa
    17041 attttcatca gcatatgcac gagcactttt aaaagattct ttaccatcta tactagtaat
    17101 tgacagtact tttgccttat cacatctaca agcgtttgat gtagcagaca ctctttttgc
    17161 gtcgctgggt attaataatt gtaccattct aaaattaaaa cattttttat agcctataaa
    17221 tgctcctgtt tcaggacaat acaatttaaa aaaacgggta ctttcatctg atattactcc
    17281 atttaaagta gcatgttcta aatttgaatt ttctaaatta gctcctctaa tatctgagtt
    17341 agataagtca caaaatctaa aacttgcacc acttaagtct gcatttttta atatagaatt
    17401 ttttaatgaa caatccgaaa gataagaatt attaaaaata gagttttcta aatctgcttt
    17461 ttctaaattt aaattgataa ggtcagacca cgaaaagtca atattactta agcagtatcc
    17521 tcttaagtcc atattttcta atcttaattc ttttaaatct gccttttctc cagcattatt
    17581 gtttttaagc cataaataat gtttctcaag tgttttttct aattcttgtt tagaaatagt
    17641 tttcattaaa atcaccttca taaatttatt tttatatatg tagtagcaaa atagtcatat
    17701 atttaattat ataacaataa ataaaaaact tctaaataat atataaaata tcatcttgaa
    17761 agtacttttt tcaatatatc agaatatatt tttaagctat ttagagataa tttaaatttt
    17821 taaacaggac ataataagct tgtattgttt tatatttgag ttgataaaaa tttctttaaa
    17881 taaaaataat gtcaattata aagtaataaa agtttagata taaaaaaatt tgtgtatata
    17941 ctatatgtag tatataatag ataaagcact gactatatgt agtgcttttg tttttgaaaa
    18001 atacttattg catttctata attatagatt aattttggga tttcaactga taagtaccaa
    18061 aagaaataat aagcaaatta agtgaaatta tggcacaaga ttatgttaaa aggacggtaa
    18121 ataatgaatt ggatagagct taacaatcaa gtgataatta aaaatgaaca aggcaagtac
    18181 caattggaaa aggataagga agccttaagt agttacatag aagaatttat acagccaaag
    18241 ttgagaaaat ttaataacct agaagaaaga ttgaagtatt taatagatga aggttattat
    18301 tcaaaagaag taataaatca gtatagcata gatgttatta aaaatatata tgatatgatt
    18361 gataaacata agtttgaatt tcaatcatat atgagtgcaa ataagtttta tcaaaattat
    18421 gcattaaaga gcaatgatgg aaaggaaata ttagaaacat ataatgataa agtgttaatt
    18481 gtagctttga cactaggaaa tggtgataaa gatttagctt taaacttggc agataaaata
    18541 gtaaaacaag aatttcaacc agctacacct acttttttaa atgctggaag aaaaagggct
    18601 ggagaaatgg tatcatgttt tttactatct gtagaagata gtacagaagg tatatcatat
    18661 gctatatctt catcaaatca cttatcaaag attggtggag gagttgcact aaatttatct
    18721 aaacttagag catctggcga atctatcaaa gatatagaag gtgcagctgg aggtgttgtt
    18781 ggagtagcta aaatgttaga acaatcattt agttacttta atcaaatggg agctagacaa
    18841 ggttctggtg cggtgtacct tactgtattc catcctgatt ttgaattgtt gatggatact
    18901 aaaaagataa atgcagatga aaaaataagg cttgctacat tatcattagg agctataata
    18961 ccagataaat ttatggagtt ggcagaaaaa aatgaagtag catatgcatt ttatcctcat
    19021 actgtgtata agaaatatgg agtttctctt gatgagatag aaatggatga gtggtatgat
    19081 aaattggtta atgatagtga tataagaaaa aaagaaataa atcctaggca gatgttgaca
    19141 aaaatagcac agatgcaaca agaaagtgga tatccatatg tagtgtacat agatacagct
    19201 aatagagaac atacattaaa agatgttgga attattaaaa tgtctaactt atgttgtgag
    19261 atatttcaat atcaaacacc ttcagaaata gaggggtatg gaggaaaaaa tgaatgggga
    19321 caagatataa gttgtaacct aggttcttta aacatagcta atgtaatgga taataaaact
    19381 atagaaagta cagttgaaac agcaataaga gcactgtcat ttgtagcaga tagcacagat
    19441 ataaaaccag tgccaacggt aagcaatagt aacagcaagt ctcattctat aggattagga
    19501 gctatgaatt tacatggata cttagtaaga gaaaatattt tatatacttc agatgatgct
    19561 atagattttt ctaatgtatt ttttgcaatg gttagatact attcaattaa agcttctatg
    19621 aaaatagcta tagaaagaaa tcaaactttt gaaggatttg ataaatcaga atatgttaag
    19681 ggaagaaata gcaaggtttt atcaaaatac tatgaacaat cttatctacc taagtcagaa
    19741 aaggtaagag cattatttga agggatttat ataccaacaa aagaagactg gacaaaatta
    19801 ttggatgagg taaaagaaaa agggatatat aatgcatatt taatggcagt agcaccaact
    19861 caaagcatta gttatgttca aaatgctaca tcaagtataa tgccaattac tgagccagta
    19921 gaagtaagaa catatggaga ctctactaca atatatccaa tgccattttt aacaaatgat
    19981 aatatgttgt attatcaatc agcatacagg atggatatga gaaaggtcat agatttagtg
    20041 gcaacagttc aaaaccatgt tgaccaaggt atatcaacaa cactgtttgt tacagatgaa
    20101 aagacaacta gagatatagc tagacattac atatatgcct ataaaaaagg tttgaaaagt
    20161 ttatattaca caagaacaaa gatgacaaga gatactcatg agtgtctagt gtgttcagta
    20221 tagggagaga aattatgaca tttaatttac ataaaataca taatgcagtt aactggaata
    20281 gagaagaaga tggatttaca caagcttttt gggaacaaaa tgtaaaacaa ttttggcttc
    20341 ctgaagaaat atctgtttct aaagacataa aggtatggaa tgaactaagt aataaagaaa
    20401 aggaattata taaaaaagta ttgggtggtt taacattact ggatacaaaa caggggaata
    20461 atggaatacc atctatgatg agtttaacag aaaacctaca aagaaaagct gtcttgtctt
    20521 ttatggggac tatggaagaa atacatgcaa aaagttattc ttctatattt atgactctac
    20581 tttctaattt agaaatagat gaattatttg aatggataga aacagaacca acattacaaa
    20641 gaaaggctga tttagtttta gctcaatacg aaaatactac aaatcaagag ggattatacc
    20701 tatcaatggt tacaagtgta tttttagaga gtttcttgtt ttattcagga ttcttttatc
    20761 cattgtatct atctggtcaa ggaaagatgg tagctagtgg agaaataata tcgcttattc
    20821 ttagagatga gtctttacat ggtaagtata taggattgct agcacaagaa atatacgatt
    20881 catttgataa aatggataag gagatgttag aagagaagat gtattctata ctttatagcc
    20941 ttatggagaa tgagatagag tatacaaatg ttatatacag agaaagtggg cttgaaaaag
    21001 aggttgtgaa ctttttaaaa tacaatgcaa atagagcttt agaaaatcta gggtttgaga
    21061 agctatatac tgtagatgct ataaatccaa ttgtattaaa tggtcttagc actgaaacca
    21121 aaacacatga ttttttttca actaagggta atggatacca aaaaggagtg tatgaggaat
    21181 tagaggatga agattttata atataattta taattatgac acactgttgt cacttttagc
    21241 gtgataatat caatgtataa aatatatatg gaggtatttt tatgaaatat gaatggagaa
    21301 aaagagataa agagttatat ttacctaaaa agaatcctgt aatagttgaa ataccagaac
    21361 agaaatttat catgttaaaa gggagtggag acccaaattc taaagaattt actgaagcaa
    21421 taggagtact ttattctttg gcatatgcaa taaaaaccat gcctaaaaaa ggaattgtac
    21481 cagaagggta ttttgactat acggtttttc ctttagaagg tatatgggat aagggagaaa
    21541 aaagtaaagg cttagatgta cttattaaag aagatttaat ttacactata atgatacgtc
    21601 agccagattt tgttacacaa gacctgttgg ataaagctac tgatatagta aagaagaaaa
    21661 aacctcataa tcttcttgaa aaagttagat ttgggtctat taatgaaggg ctatgtgttc
    21721 aaatgcttca tataggttca tatgataatg aaccagaaag ctttgacatt atgaacgaat
    21781 tttgcaaaaa aaataaactt ataagaaaat cttacacaca tcgtgaaatt tatataagtg
    21841 atgctagaaa agtatcgcct gaatcattga agacggtttt acgttttgaa gtagaaaggg
    21901 aagtataaat attttgaata atttataaga gttataaaaa gtgaagtctg ttgagacttc
    21961 attttttgat gcaattttaa aattaaattt gatgtttcat aatattttaa aaactttcta
    22021 cttttattag tgtgaataac tgttgctatt aaataataat actaattata taagtattat
    22081 tatataat
//
LOCUS       DAMJVG010000063        21915 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.063, whole genome shotgun sequence.
ACCESSION   DAMJVG010000063 DAMJVG010000000
VERSION     DAMJVG010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21915)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21915)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21915
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.063"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            269..1867
                     /locus_tag="PC512_002632"
     CDS             269..1867
                     /locus_tag="PC512_002632"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative manganese-dependent inorganic
                     diphosphatase"
                     /protein_id="HDF2442367.1"
                     /translation="MSLLVFGHKNPDTDSICSAISLAHLKNKLGIKATAYALGDIRKE
                     AKYALDYFKVDAPEILDNVRIQVRDLNYDKVVPLTPTSSILEAYNLMDEKNVKTLPVT
                     YDDGTFAGIITMKEIAKNLLHQHFTTIHTSLSNICKNLNGTILVDCGEDIKGRVVTLS
                     FGMETLIETLKEGDIAIVGDRYDSIEYAIDTKVKLLILTNHTEISKDLLALAKINGVS
                     VVSVESDNYKTSNVINQCSFLDSIEATENLITFKEDDYMDEIKEIMLETNFRSYPILD
                     DDNKFLGLVSKGHLLNPSKKNVVLVDHNEYAQSADGIEQANIVEIIDHHKLGGISTDV
                     PMSFRVMPVGCNSTIIYQMYKENNVEIPYEIAGLLLSAILSDTLLFKSPTTTDMDKKA
                     CEELSKIAKVDMEKYAMDMFKCGTSLDEYTIEEIVNMDFKEFNMSGHRVGIGQVFTLD
                     IDSIFAKKDEFLSYINSTDYDKLILSVTDIIKEGSYLIYKAEDSLIANAFGVEGVQGT
                     FAPGVVSRKKQLVPNLTTAIKNFK"
     gene            complement(2102..4183)
                     /gene="bclA1"
                     /locus_tag="PC512_002633"
     CDS             complement(2102..4183)
                     /gene="bclA1"
                     /locus_tag="PC512_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA1"
                     /protein_id="HDF2442368.1"
                     /translation="MRNIILYLNDDTFISKKYPDKNFSNLDYCLIGSKCSNSFVKEKL
                     ITFFKVRIPDILKDKSILKAELFIHIDSNKNHIFKEKVDIEIKRISEYYNLRTITWND
                     RVSMENIRGYLPIGISDTSNYICLNITGTIKAWAMNKYPNYGLALSLNYPYQILEFTS
                     SRGCNKPYILVTFEDRIIDNCYPKCECLPIRITGPMGPRGATGSTGPTGVTGPTGSTG
                     ATGSIGPTGPTGNTGATGSIGPTGVTGPTGSTGATGSIGPTGVTGPTGNTGVTGSIGP
                     TGATGPTGVTGEIGPTGVTGPTGVTGSIGPTGATGPTGATGVTGEIGPTGATGPTGNT
                     GVTGATGPTGNTGVTGVTGATGPTGATGVTGEIGPTGATGPTGEIGPTGATGPTGATG
                     VTGEIGPTGVTGPTGEIGPTGATGPTGVTGSIGPTGATGVTGEIGPTGPTGVTGSIGP
                     TGATGPTGNTGVTGVTGPTGATGPTGVTGEIGPTGATGPTGVTGEIGPTGATGPTGPT
                     GNTGATGSIGPTGVTGPTGATGATGVTGPTGPTGATGNSSQPVANFLVNAPSPQTLNN
                     GDAITGWQTIIGNSSSITVDANGTFTVQENGVYYISVSVALQPGSSSINQYSFAILFP
                     ILGGKDLAGLTTEPGGGGVLSGYFAGFLFGGTTFTINNFSSTTVGIRNGQSAGTAATL
                     TIFRIADTVMT"
     gene            complement(4861..5385)
                     /locus_tag="PC512_002634"
     CDS             complement(4861..5385)
                     /locus_tag="PC512_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDF2442369.1"
                     /translation="MENKNPIVTIEMENGKEIKIELYPNIAPNTVKNFVSLVNEGYYN
                     GIIFHRVIPGFMIQGGCPNGTGMGGPGHSIKGEFSGNGFTNNLKHERGVISMARTMAP
                     NSAGSQFFIMHKNSPHLDGQYAGFGRVIEGMDTVDEIASVRTDSADKPQTPQIMKSVT
                     VETFGIDYSDVEKN"
     gene            complement(5450..6202)
                     /locus_tag="PC512_002635"
     CDS             complement(5450..6202)
                     /locus_tag="PC512_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HDF2442370.1"
                     /translation="MKLGLCLEGGGAKGAYQAGVVKALYDGGINKFYSISGTSIGAIN
                     GYYLYTGNVDNLEKMWTNIKDIQNGNVKIVNNTVDNSPAIDNLRELDDSNIEEMNFYV
                     NYVEVDNKVVSEKIVDVSKMPRNEAIISISYSGLLPSNPNATLGFKEQFVKDVQEGIY
                     DGFKLDGGLIRSALIEPLIGDNVDKIILISTKYNYELPEDIKKVYDEDKIIVVRPNTQ
                     FAPKDTLNFDDEFCKTIYQEGYEIGKNILDRL"
     gene            complement(6233..7531)
                     /locus_tag="PC512_002636"
     CDS             complement(6233..7531)
                     /locus_tag="PC512_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M18 family aminopeptidase"
                     /protein_id="HDF2442371.1"
                     /translation="MDSINFAKNLIDFIYDSPSSFHAVKSTKEILDKNGFEELVLNQR
                     WNLRVGGKYYVTKNLSAIVAFVVNSEDIERDGFRIIGSHSDSPTFSIKPNAEIEAEKS
                     YLKLNTECYGGAILSTWLDRPLGIAGRVVLKGDSILKPNERLIDFKKPICIIPNLAIH
                     LNRSINDGHSYNKQKDMLPLVGMLNDTLEKDNFLIKQIASNLDVNMDDIIDFDLFLYE
                     FEKGSLIGANDEFISIGRQDNLAMVHASLNALVNTKGQHGVNVMAVFDNEEVGSSTKQ
                     GADSNMLLNILERICISMGKDREGFFESIYSSFMISSDLAHAIHPNIPEKHDPTNKPI
                     MGKGPVIKINASQAYTSDGYSIAIYKNICREANVEYQEFVNRSDERGGSTIGPISSTH
                     IDIPSVDVGSPILAMHSIRELGNVEDHYSIYKTFSKFFEI"
     gene            complement(7548..9812)
                     /locus_tag="PC512_002637"
     CDS             complement(7548..9812)
                     /locus_tag="PC512_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3553 domain-containing protein"
                     /protein_id="HDF2442372.1"
                     /translation="MNLDTLNPAQREAVEKTEGPVLILAGAGSGKTKVLTTRIAYLIE
                     DKGVQAPNILAITFTNKAANEMRERVEQNIGPETKDMWISTFHSCCVRILRKDINKIG
                     YNRSFVIYDSADQVTLVKDCLKELNLSDKVFEPKAVISAISGAKDKLYTPKQFKDINM
                     ADNRMVKIADIYALYQDRLKRNSALDFDDLILKTVELFKANDEVLAYYRSRFRYIMVD
                     EYQDTSKAQYELIKLLAREHQNICVVGDDDQSIYGWRGADIRNILEFEKDYDNVHVVK
                     LEQNYRSTQVILDAANKVISNNIERKRKKLWSEKKEGELIKIQLTGSEIEEADFIADS
                     IAQIARKENRPYKDFAVLYRANAQARPVEDALNRSQIPYNIYGGTKFYERKEIKDLLA
                     YLRVIQNPQDDISIKRIINVPRRGIGLRTIEKIEDRANLKQESIYSVLIDIETNSDIS
                     TKARASISGFVDIIGTLRTIKEVYPVSKLIEKVLDTTGYMDELVEIRNKNEKDLTGKG
                     EEAQDRIDNLREFISIALEFESSNDDTYENKDLETFLTSIALTSESNDEEDNDRVSLM
                     TIHTSKGLEFPVVFLTGMEEGLFPISRAIKSMSDSQIEEERRLCYVGITRAKEELYMS
                     LTEKRTLYGKTNVAIASRFMEELPEECIERLYKVKKELSYSKASYNMLDKYTKKYMST
                     ISKSKVADKVNATIKDSNKETNPDDIKLGSKVHHPKFGVGTVVSIIGTDVTIAFDQQG
                     IKKINKEYTTLNIL"
     gene            complement(10067..10885)
                     /locus_tag="PC512_002638"
     CDS             complement(10067..10885)
                     /locus_tag="PC512_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HDF2442373.1"
                     /translation="MFKINNLTYQYEKNTNALLNINMDFSKGNVIGIIGSNGSGKSTL
                     FMNLMGILKPTSGEILFKEEKLKYDKRSLYNLRKNVGIVFQDPEKQIFYSKVYDDIAF
                     AMRNIGMDEKTIKERINKALVAVNGIDFIDRPVHFLSYGQKKRVAIASVIAMENEIVL
                     LDEPTAGLDPVSTRSIVDIIKGLNKNNIKIVISSHDMNLMYEICDYIYVLDKGILIDE
                     GKAENVFINENNIIQAGLESPWLVKVHRNMNLPLFKKEEDLYKYWKERELNTNK"
     gene            complement(10878..11576)
                     /gene="cbiQ"
                     /locus_tag="PC512_002639"
     CDS             complement(10878..11576)
                     /gene="cbiQ"
                     /locus_tag="PC512_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ECF transporter T component CbiQ"
                     /protein_id="HDF2442374.1"
                     /translation="MLIIDKYAYTNRLSKVNPNKKVAIGVIFLIASMVIQNIFILSGI
                     MILMSILVVCVAGIDLKNYLKLLRIPMYFLFLSIGITLVNISFNKADLLYSFEFFSFN
                     VGISKASIDMSIHVLFRAMSCLTCVYFCILTTPFNQLIFFFKKLHLPDTFVELSMLIY
                     RFIFIFLEEFSEIYKSQELRFGYINLKTSYKSLGILGSMLYKRLMTRYDDMCISLDIK
                     LYDGKFHIVGDNDV"
     gene            complement(11579..11857)
                     /locus_tag="PC512_002640"
     CDS             complement(11579..11857)
                     /locus_tag="PC512_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF2442375.1"
                     /translation="MSAKTKTNILLLLLVVALIIFPLLVNSGAEYGGADGQAESEITK
                     INPNYKPWFSSPYEPPSGEIESLLFSAQAALGAGVIGYILGLQKGKRS"
     gene            complement(11847..12599)
                     /locus_tag="PC512_002641"
     CDS             complement(11847..12599)
                     /locus_tag="PC512_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter permease"
                     /protein_id="HDF2442376.1"
                     /translation="MKQNIKLGVIAALMLIILTPVTSNAMHIMEGYLPVKWSIAWGVI
                     FIPFFLFGLKSIGKIVKQDPKKKVLLALCGAFVFVLSALKIPSVTGSCSHPTGVGLGA
                     IMFGPSVMFVLGTIVLIFQALLLAHGGITTLGANAFSMAIIGPIVSFLIFKALKKKDG
                     NNAIPVFLAAAIGDLATYTITSIQLALAFPDPSGGVMASAIKFLGIFFMTQIPIAIAE
                     GILTVIVYNLITENGEKSILENNDKGVKANEC"
     regulatory      complement(12781..12973)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            complement(13105..14877)
                     /locus_tag="PC512_002642"
     CDS             complement(13105..14877)
                     /locus_tag="PC512_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide reductase activation-like protein"
                     /protein_id="HDF2442377.1"
                     /translation="MKWIYDDYEFENRANNLSWTIAGDYNESIDISEKDYSSKEIGLY
                     FAIIAGARRKYVDWDIVKKYLTNRIRKGYNKDIILGLIQVILNTIVEEKVIKDRPGIE
                     DIRRNAYKDIVSRFTKIHNDNIMDKIKYTFVLYSMDKHPALDSMTRRIVNDIRNIDTN
                     QDIMEILKALDVIYLTYFEYILNGEENSLIDENNVESVEVNFDTFADFMYEELYSDEE
                     ENIIESDIDSISSSMLVEGVGDFDDSKCSNSADRVIYVDEDTANKIYSKIEHYYGKTY
                     LSKGEIKKIETQNCRNVHEGCRIHFTDGVLRSECNNVFQLKYVTRQKENNLGKFREHA
                     RMYRQQIKRLKESLSRILIEENAKSRVYSDCGTILANRAWRVGRSNNNKIFYKDIENE
                     KGKYVIDILLDASGSQSRNQGNVAIQAYIIANALTEVGIPNRVMGFSSFLDYTILKRF
                     KDYDDSIKNSENIFEYFCAGNNRDGLAIKSICSGLINRDEENKILIVLSDGRPNDVKI
                     GKSSERTLRGEKAYRGIVGLRDTANEVRKARKQNILVLGVFTGKESELEAERLIYGND
                     FIYSRDITRFSDVVSMYLKKIIRN"
     gene            complement(14891..15820)
                     /locus_tag="PC512_002643"
     CDS             complement(14891..15820)
                     /locus_tag="PC512_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2442378.1"
                     /translation="MDIIDNLRVQGVDEKLIEDVLYFRNYYGLEKDLEYRVTKSKTYF
                     YGKDILSMCIAAILEEENILLSGPKATGKNLLADNLGEIFNRPQWNTSFHINTDSSTL
                     IGTDTFIDNEVKLRRGSVYECAINGGFGVFDEINMAKNDAIVVVHSALDYRRIIDVPG
                     YERVNLHPATRFIGTMNYEYAGTKELNEALVSRFMVIDIPPIEEDKLMMILKNEFSDA
                     DEEKLIHFAGIFLDLQLKSQNGEISSKAIDLRGLMASLKTIRRGLKPTLAINMGLTGK
                     TFDVYEKEMVGDVIKTRIPNKWESIDVFPISHI"
     gene            16049..16237
                     /locus_tag="PC512_002644"
     CDS             16049..16237
                     /locus_tag="PC512_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2442379.1"
                     /translation="MEYMSCPEVAKKWGISERRVQKLCEESRIPGVSKLGYMWLIPKN
                     AEKPVDGRTKRRKEVQYE"
     gene            16230..16931
                     /locus_tag="PC512_002645"
     CDS             16230..16931
                     /locus_tag="PC512_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2442380.1"
                     /translation="MNSVLIIDDDKELCALMKKCVEQENLSAITAHGGAEGLHLVDKN
                     RHTLSLVILDIMMPDIDGFQVLKKIRETSNIPVIMLTAKNDEDDKVSGLRLGADDYLT
                     KPFSINELMARVNSLIRRYTMLNPAFITDTDFIIINGMIIDKTNRIVSVNNIPVQLTS
                     KEFDLLAFLASNKGRVFTKKQIYTQVWEEEYAFDDSNIMSFISKLRKKIEPDPNHPFY
                     ILTVRGVGYRFNKEA"
     gene            16933..17856
                     /locus_tag="PC512_002646"
     CDS             16933..17856
                     /locus_tag="PC512_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2442381.1"
                     /translation="MNTSVYLLLILALSLIIIAYLVSVLLRVRIQLTLIKDALEDIKN
                     GNLNRRILTDENDITKQICYDINEIAINSQFQLIQQKQSEQAYKQLMTSLSHDVKTPL
                     ASLVGYLEAVESKIVVGEEKDEYIHVASNKAHYLKNFVENLFEWVKLDSKEQVFHFDI
                     FDLNELSRNIISDWIPVLESSHFEYEFDIPEIEYFLRIDANAYTRIINNLLQNIITHS
                     SGNKMTLRIFENKEQAQIIITDNGKGISSDNLPHIFERLYQCDHSRASKGNGLGLAIA
                     KELINAHKGNITANSTPGMGTEFTILLPKAL"
     gene            18013..18936
                     /locus_tag="PC512_002647"
     CDS             18013..18936
                     /locus_tag="PC512_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019639192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2442382.1"
                     /translation="MNDFVIETKQLTKIYGNQTVVDKVNLHVKKGRIYGLLGRNGAGK
                     TTIMKMILGLTSITYGEVDVFGENIKGREKQVYPRIGAIIETPGFYPNLTGTENLEIF
                     AKLRGTAAPNSVKRALEIVGLPYKNKKLFSKYSLGMKQRLGIANAILHDPELLVLDEP
                     TNGLDPIGIAEMRKFIRDLSVEHGKTILISSHILSEISLLADDIGIIDHGVLLEESSM
                     SELEKKNSKYILLQVSDIPKTSLILERQFNTKDYSVQDDYTLHLYNTNLDMGEINKAL
                     VMQNVTVISSQLCNDTLEDYFKKITGGEGIA"
     gene            18929..19666
                     /locus_tag="PC512_002648"
     CDS             18929..19666
                     /locus_tag="PC512_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2442383.1"
                     /translation="MLKLIQTEFLKLRRRKLIWLMLLSALIMPFFALLYFNYFGKTGV
                     EPIKFYKWSAFGYTLWIILPVVLGIFCTMLIHEENQYDMLKQLWIVPISKMGYFFSKF
                     FVVLIYSICFMLITAVASVLFSVLSGYVVFSWASILYLLKKCLEIGVITAFVMLPILA
                     IATSQKGYILPICITLVYAFSGFVIMTINMYLHPLSSMGVIIMRNKDIPGLIFSQEIN
                     VPLAFLCICIWSIVSVLFANIALGRRK"
     gene            19677..20450
                     /locus_tag="PC512_002649"
     CDS             19677..20450
                     /locus_tag="PC512_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2442384.1"
                     /translation="MWKLLWAECQKIRRSKIVWITVFASIMIAVIVFAGGQDVYNDPD
                     LHYGLKSVYDGSRYIDNAGWYMDAVQPWSTFFVLPAVIALLGSYIICREEEEDTIKSL
                     RLIPINETNLTIAKMIITFIFSILLYLLLFTITFLTESVLHFSDLSTKLVLSCMKEYF
                     LDGIGVFFAISPIIALVSRMKKGYWLALVFTEVYSIAGLFAGMSNVLQTFFPIAAIFN
                     ISGYYITTGEKIMGSIMSLLLCACLSAFILKGLKHNEKN"
     gene            complement(20991..21599)
                     /locus_tag="PC512_002650"
     CDS             complement(20991..21599)
                     /locus_tag="PC512_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HDF2442385.1"
                     /translation="MSVINSFILQYGLISVFVLIMIEYACFPLPSEVVLPLCGAIAAR
                     NHFGFLTILILSIIAGILGSIFCYTVGNWGGKSIINKIIEICPKAKKGIFASQDYFNK
                     YSSISVCVCRLIPLCRTYISFIAGIAGQNIITFVISSIVGITIWNTSLISIGYIFSES
                     WVRIMSHYNDYKFLVLIIPISIIFIGFVIKSFIHKKHHKIRL"
     gene            complement(21777..21893)
                     /gene="rrf"
                     /locus_tag="PC512_002651"
     rRNA            complement(21777..21893)
                     /gene="rrf"
                     /locus_tag="PC512_002651"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         6971 a         3796 c         2873 g         8275 t
ORIGIN      
        1 ttaatttatt aacatattaa ttaatttttt cccaggtaga tttaatcaat ttattttaaa
       61 taaaagtaaa tttaattcga tatttgattg ggtaaaagta tatataataa taatttttat
      121 attaaatttg tagtatttat gtaagaaata aattttatat aatatttttt cactaaattt
      181 ttttcttttt acaacaaata ctcactacct tttgatataa tatttttatc aattattatt
      241 atattcaagt tttgaaagga gtattaaaat gagtttatta gttttcggac ataaaaatcc
      301 agatacagat tcaatatgtt ctgcaatttc attagcacat ttaaagaaca aactaggaat
      361 aaaagcaaca gcttatgctt taggagatat cagaaaagaa gctaaatatg ccttggatta
      421 ctttaaggta gatgcacctg aaattttaga taatgttaga atacaagtta gagatttaaa
      481 ttatgataaa gtagtacctt taacaccaac ttcatctata ttagaggctt ataaccttat
      541 ggatgaaaaa aatgttaaaa cactacctgt aacttatgat gatggaactt ttgctggtat
      601 cattactatg aaagaaatag ctaaaaatct acttcatcaa cactttacaa ctatacacac
      661 atcactatca aacatttgta aaaaccttaa tggtactatt cttgtggact gtggtgaaga
      721 tataaaaggt agagtagtca ctttatcatt tggaatggag actctaatag agactttaaa
      781 agaaggagac atagctattg ttggagatag atatgatagt attgaatatg ctattgatac
      841 aaaagttaaa cttttaatac ttactaatca tacagagatt tcaaaagatt tgctagctct
      901 tgctaagata aatggagtgt ctgttgtttc tgttgaaagt gacaattata aaacttctaa
      961 tgtaataaat caatgtagtt tcttagactc tatagaagct acagaaaatt taattacatt
     1021 caaagaagat gattatatgg atgaaataaa agagattatg ctagaaacaa acttcagatc
     1081 ttatccaata ttagatgatg ataataagtt tttaggttta gtttcaaaag gtcatctatt
     1141 aaacccatct aaaaagaatg ttgttttagt tgaccataac gaatatgctc aaagtgctga
     1201 tggaattgaa caagcaaaca tagttgaaat aattgaccat cataaacttg gcggtatttc
     1261 tactgatgtt cctatgtcat ttagagttat gcctgttgga tgcaatagta ctataattta
     1321 tcaaatgtac aaagaaaata atgttgagat accttatgaa atagctgggc ttcttttatc
     1381 tgctatatta tcagatacat tattatttaa gtctccaaca acaactgata tggataagaa
     1441 agcttgtgaa gaattaagta aaatagcaaa agtagacatg gaaaaatacg ctatggatat
     1501 gtttaaatgc ggtacttctt tagatgaata tactatagaa gaaatagtaa atatggactt
     1561 taaagaattt aatatgagtg gacatagagt tggtattgga caagtattta ccttagacat
     1621 agactctata tttgctaaaa aagatgagtt tttatcttat ataaattcga ctgattatga
     1681 taaattaatt ctttcagtta cagatataat caaagaaggt tcttatttaa tctataaagc
     1741 agaagatagc ttaattgcta acgcatttgg tgttgaaggt gttcaaggca catttgcacc
     1801 aggtgttgta tcaagaaaaa aacaattagt ccctaattta actactgcaa tcaaaaattt
     1861 taaataatat aaaattttta aataacgaaa actgtctcaa atctatattt gagacagttt
     1921 tttattatat atatattgat aataaagtta aataaaaatc cataaattta aaatttttat
     1981 gaatatattt tattattatt gttattttat tcattctaaa ataggtaaaa ctcaatatat
     2041 aaaaatactt ttgtcattta aataaaacct aaatagtttt taagattatt ttagacacgt
     2101 tttaagtcat aacagtatca gctattctaa atatcgtcaa agtagccgca gttcctgctg
     2161 attgcccatt tcgtatccct actgttgtag atgaaaagtt atttattgta aaagtagtcc
     2221 caccaaataa aaaaccagca aaatatccag aaagtactcc tccgcctcct ggctcagtag
     2281 taagccctgc caaatctttt cctcctaaaa ttgggaatag gatagcgaaa gaatattgat
     2341 ttatacttga tgaacctggt tgtaatgcta ctgaaactga tatataatac acaccatttt
     2401 cttgtactgt aaacgtacca tttgcatcta ctgttatact tgaactattt cctattattg
     2461 tttgccaacc tgttatagca tctccattat ttagtgtttg tggagatggt gcatttacga
     2521 ggaagttagc aactggctga gaggaattgc ctgttgctcc tgttggacct gttgggcctg
     2581 ttactcctgt cgctcctgtt gctcctgttg gacctgttac tcccgttggc cctatacttc
     2641 ctgtcgctcc tgtatttcct gttgggcctg ttggtcctgt tgctcccgtt ggtcctattt
     2701 ctcctgttac tcctgttggg cctgttgctc ccgttggtcc tatttctcct gtcactcctg
     2761 ttgggcctgt tgctcccgtt gggcctgtta ctcctgtcac tcctgtattt cctgtcggtc
     2821 ctgttgctcc cgttggtcct atacttcctg tcactcctgt tgggcctgtt ggtcctattt
     2881 ctcctgtcac tcctgtcgct cctgttggtc ctatacttcc tgtcactcct gttggtcctg
     2941 ttgctcctgt tggtcctatt tctcctgttg ggcctgttac tcctgttggc cctatttctc
     3001 ctgtcactcc tgtcgctcct gttgggcctg ttgctcccgt tggtcctatt tctcctgttg
     3061 ggcctgttgc tcctgttggc cctatttctc ctgtcactcc tgtcgctcct gttggacctg
     3121 ttgctcctgt tactcctgtt actcctgtat ttcctgttgg acctgttgct cctgttactc
     3181 ctgtatttcc tgttggacct gttgctcccg ttggtcctat ttctcctgtc actcctgtcg
     3241 ctcctgttgg acctgttgct cctgttggtc ctatacttcc tgtcactcct gttgggcctg
     3301 ttactcccgt tgggcctatt tctcctgtca ctcctgttgg gcctgttgct cccgttgggc
     3361 ctatacttcc tgtcactccc gtatttcctg tcggacctgt tactcctgtt ggtcctatac
     3421 ttcctgtcgc tcctgtactt ccggttgggc ctgttactcc cgttggccct atacttcctg
     3481 ttgctcctgt atttccggtt gggcctgttg gtcctatgct tcctgtcgct cctgtacttc
     3541 cggttgggcc tgttactcct gttgggcctg tacttcctgt cgctcctctt ggtcccattg
     3601 gacctgtaat tctaattgga agacactcac atttaggata acaattatct ataattctat
     3661 cttcaaatgt tacaagtata tacggtttgt tacaacctct actagatgta aattcaagaa
     3721 tctgataagg gtaatttaaa gataaagcta acccataatt aggatattta ttcattgccc
     3781 atgcttttat agttcccgta atatttaaac aaatatagtt ggatgtatca cttatcccaa
     3841 ttggtaaata tcccctgata ttttccatag acactctatc attccatgtt atagttcgta
     3901 aattataata ttcacttatt cttttaattt caatatctac tttttcttta aaaatatgat
     3961 tcttatttga atcaatatga ataaataact ctgcttttaa tatacttttg tcttttaata
     4021 tatctggtat tctcacttta aaaaaagtaa tcaacttttc ttttacaaaa ctatttgaac
     4081 atttacttcc tattaagcaa taatctaaat tactaaagtt tttatctgga tattttttag
     4141 atataaaagt atcatcattt aaataaagta taatatttct catttataat ccctccattt
     4201 tgggtctata tcatactatg tttaaaatac atgcttagtt acaatacaat taaaatttat
     4261 agtattaaat ttttatataa taatgctgat ttctacaaaa aaagaacatg tcattagaaa
     4321 tttctaatag catgttcttt ttcattatta tatattacac tttaaattat tccttgactg
     4381 gcttagctgg tgtaaactaa accagtcttt ctaaaatatt aagcactttt ttcttattat
     4441 gttttttagg atttattgtc tatattattg taaaccaaag ttataaaatt gtaaatagaa
     4501 tatattacca taacaatatt tttttataag taaaaattat aaaaaacttt atttttgtta
     4561 aatggaataa ataaaataag tttaaaaaat actgaaataa gtgttttcca catattttat
     4621 atatttattt aatacattat tatttaaaaa taaatatata aacaatcata ataaaatttt
     4681 tttaataaaa ctttattttt tagttaaaat catacaatat atagatttcc acaatacaaa
     4741 taaattaaaa agtgaaatgt atttgtctaa aaacataata acatttcact ttatcctcat
     4801 ttttaagtaa tatatatttt taatttttat ttataactaa atctagtttt tatataaatt
     4861 ttagtttttt tctacatctg agtaatctat tccaaaagtt tctacagtaa cagatttcat
     4921 aatttgtgga gtttgtggct tatcagctga atctgttcta actgatgcta tttcatcaac
     4981 tgtatccata ccttctatca ctctaccaaa acctgcatac tgaccatcta agtgtggtga
     5041 gtttttatgc attatgaaaa attgagaacc agctgaatta ggtgccatag ttctagccat
     5101 tgatatgact cctctttcat gttttaaatt gttagtaaat ccattaccac taaattcacc
     5161 ttttattgag tgacctggac cacccattcc tgtaccattt gggcatcctc cttgtatcat
     5221 aaatcctggt attactctat gaaatattat tccattgtaa tatccttcat ttactaatga
     5281 tacaaagttt ttaactgtat ttggagctat atttggatat aactcaattt tgatttcttt
     5341 tccattttcc atttctatag ttactatagg atttttattt tccataattt attaccttcc
     5401 ttttcattag ttaaattaca taattacatt tattatatta tactctaaat taaagtctat
     5461 caagtatatt ttttcctatt tcatatcctt cttgataaat agttttacaa aactcatcat
     5521 caaagttaag cgtgtcttta ggagcaaatt gagtattagg tctaactact attattttat
     5581 cttcatcata tactttttta atatcttctg gcaactcata attatatttt gtggatatta
     5641 aaataatttt atccacatta tccccaatta atggttcaat taatgcactc ctaattaaac
     5701 ctccatctaa tttgaaacca tcataaattc cttcttgcac atctttcaca aattgttctt
     5761 taaatccaag agttgcgttt ggatttgatg gtaacaaccc actgtatgaa atgctgataa
     5821 tggcttcatt acgaggcatt tttgatacat caacaatctt ttctgatact actttattat
     5881 caacttcaac ataattaaca taaaagttca tttcttctat attactatca tctagttccc
     5941 ttaggttgtc tatagcagga gaattatcca cagtattatt tactattttt acatttccat
     6001 tctggatatc ttttatattt gtccacattt tctccaagtt atcaacattc cctgtgtaca
     6061 aataatatcc atttattgct cctattgatg tccctgaaat cgaataaaat ttatttattc
     6121 ctccatcata caaggcttta actactcctg cttgataagc cccttttgct cctccacctt
     6181 ctaaacataa tcctaatttc atagtctcat ctccaaattg tttatcttat atttatattt
     6241 caaaaaactt actaaatgtt ttatatatac tatagtggtc ctcaacattt cctaattctc
     6301 ttatagaatg cattgctaaa attggacttc ccacatccac agatggtata tctatatgag
     6361 tagaagatat tggacctata gtacttcctc ctctttcatc tgacctatta acaaattctt
     6421 gatactcaac attagcttct ctacatatat ttttataaat agctatagaa tatccatcac
     6481 tagtatacgc ctgactagca tttatcttta taaccggacc ttttcccatt attggtttat
     6541 tagttgggtc atgcttttct ggaatgtttg gatgaatagc atgagctaaa tctgatgata
     6601 tcataaaaga tgaataaata gactcaaaga atccctctct atccttaccc attgatatac
     6661 aaattctctc caatatattt aacaacatgt ttgaatctgc accttgttta gtagagctac
     6721 caacttcttc attgtcaaat acagccatta catttacacc atgttgacct ttagtattaa
     6781 caagagcatt caaactagca tgtaccattg caagattatc ttgtctccca atagatataa
     6841 attcatcatt agcccctatt aaacttcctt tttcaaattc atataaaaat aaatcaaaat
     6901 ctataatatc gtccatattt acatctaagt tagatgctat ttgctttata agaaaattat
     6961 ctttttctaa tgtatcattt aacatcccaa ctaaaggtaa catatctttt tgcttattat
     7021 atgaatgacc atcatttata cttctattta aatgtattgc tagatttggt attatacaaa
     7081 ttggcttttt aaagtctata agcctttcat ttggttttaa tatactatca ccttttaaaa
     7141 ctactctacc agctatccca agaggtctat ccaaccatgt acttaatatt gctcctccat
     7201 agcattctgt atttaacttc aaataagatt tttcagcttc tatttctgca tttggtttaa
     7261 tactaaatgt aggagaatct gaatgagagc ctattattct aaatccatct ctttctatat
     7321 cttctgaatt tactacaaaa gctactatag ctgataaatt cttagtaaca taatactttc
     7381 caccaactct tagattccat ctttgattca aaactaattc ttcaaatcca tttttatcta
     7441 agatttcctt agtactcttg actgcatgaa aagacgacgg actatcatat atgaagtcta
     7501 ttaagttttt agcaaagttt atactatcca ttcctcattt acctccatta taaaatattt
     7561 agtgttgtat attctttatt tattttttta attccctgtt ggtcaaaagc tatagtaaca
     7621 tctgtaccaa ttatagaaac cactgtccca accccaaatt taggatgatg taccttagaa
     7681 ccaagtttta tatcatctgg attagtttct ttattagaat cttttattgt agcattaact
     7741 ttatctgcaa ctttagattt gcttatagta ctcatatact ttttagtata tttatctaac
     7801 atattataac ttgctttaga atagcttagt tcttttttta ctttgtacaa tctttctata
     7861 cattcttctg gcagttcttc cataaatctt gaagctattg caacatttgt tttaccatat
     7921 aatgttctct tctctgtcaa tgacatatat agctcttctt tagctctagt tataccaaca
     7981 taacaaagtc ttctctcttc ttctatttgt gaatcactca tagattttat agctcttgat
     8041 ataggaaata acccttcttc catacctgtt aaaaacacaa cagggaactc taaaccttta
     8101 gatgtatgaa ttgtcataag cgaaacccta tcattgtctt cttcatcatt tgattcagat
     8161 gtaagtgcta tacttgttag gaatgtctct aagtctttat tttcataagt atcatcatta
     8221 ctactttcaa actccaaagc tatagaaata aattctctca aattatcaat tctgtcttga
     8281 gcttcttcac ctttgcctgt taaatctttt tcatttttat ttcttatctc tacaagctcg
     8341 tccatatatc ctgtagtgtc caagactttt tctataagtt tgctaacagg ataaacttct
     8401 tttatagttc taagagtccc tataatatca acaaatccac ttatacttgc ccttgcctta
     8461 gtagatatat ctgaatttgt ttctatatca attaatactg agtatatact ttcctgtttt
     8521 aagttagctc tatcttcaat tttttctatg gttctaagcc ctatacctct tctaggaaca
     8581 tttataatcc tttttataga tatatcatct tgtggatttt gaataactct taaatacgcc
     8641 aacaaatcct ttatttcttt tctctcatag aattttgtac caccatatat attgtatgga
     8701 atttgacttc tatttaaagc gtcctctaca ggtcttgcct gtgcatttgc tctataaagt
     8761 actgcaaaat ccttataagg tctattttct tttctagcta tttgtgcaat tgaatcagca
     8821 atgaaatcag cctcttctat ttcactacca gttaattgta tctttataag ttctccttct
     8881 tttttttcac tccaaagctt ttttcttttt ctttctatat tattagatat aactttatta
     8941 gctgcatcta atatcacttg tgtagaccta taattttgtt ccaactttac aacatgtaca
     9001 ttgtcataat ctttctcaaa ttcaagtatg tttcttatat ctgcacctct ccatccataa
     9061 atactttggt catcatctcc aacaacacaa atattttgat gttctcttgc taataatttt
     9121 atcaattcat attgagcttt acttgtatct tggtactcat ctaccattat gtatctaaat
     9181 ctacttctgt aatatgctaa cacttcatca ttagccttga aaagttctac agttttaagt
     9241 attaaatcat caaagtcaag tgcactattt ctttttaaac ggtcttgata tagcgcataa
     9301 atatctgcaa tcttaaccat tctattatct gccatattga tatctttaaa ctgctttgga
     9361 gtataaagtt tatcttttgc tcctgaaatt gcacttataa ctgcttttgg ttcaaacact
     9421 ttatcactta aatttaattc ttttagacag tctttaacca atgtaacttg gtctgctgaa
     9481 tcataaatta caaaacttct attgtaacca atcttattta tatcttttct tagtatacga
     9541 acacagcaag aatggaatgt acttatccac atatccttag tttcaggacc tatattttgt
     9601 tcaactctct ctctcatttc atttgcagct ttgtttgtaa atgttatagc taatatattt
     9661 ggtgcttgta cacctttatc ttctataaga tatgctattc ttgttgttaa taccttagtt
     9721 ttacctgaac cagcaccagc cagtataagt actggacctt cagtcttttc tactgcttct
     9781 ctttgagcag gatttaatgt atctaaattc atatttctcc tcctgttaac agccataaat
     9841 atattttaat ctaaaatatg aattacttca aattataatt atgtattata ttaatagatt
     9901 atttccaata tattacaatt aaataacatt tttccatata atttatttca ttgtttaata
     9961 aaaaaaataa ccttatgatt tggggaatca taaggcacct ttaaggggtc taggttaagg
    10021 gttattatat ataaatctat ttttttaaaa taggtttagg gcttaattat ttatttgtat
    10081 taagttctct ttccttccaa tacttataca aatcttcttc tttcttaaat aagggtaaat
    10141 tcatatttct atgtactttt actaaccatg gggattctag gccagcttgt ataatattat
    10201 tttcatttat aaacacattt tctgcttttc cttcatcaat caaaatcccc ttatccaata
    10261 catatatgta atcacatatt tcatacatta aattcatatc atgactggat attactattt
    10321 ttatattatt tttatttaat ccctttatta tatctacaat agacctagta cttactgggt
    10381 ctaaaccagc tgtaggttca tcaagtaata caatttcatt ttccattgct ataactgatg
    10441 ctattgccac tctttttttc tgtccatagc taagaaaatg tactggcctg tctataaaat
    10501 ctattccatt aacagctact agagctttgt ttattctctc tttaattgtt ttttcatcca
    10561 taccaatgtt tctcattgca aaggctatat catcatatac ttttgaataa aaaatttgtt
    10621 tttctgggtc ttggaacaca atacctacat tttttctaag gttgtataaa cttctcttat
    10681 catattttaa cttttcttct ttaaaaagaa tttctccaga tgtaggcttt aatataccca
    10741 ttaaattcat aaataatgtt gattttcctg aaccatttga acctattata cctataacat
    10801 ttccctttga aaaatccata ttaatgttta atagtgcatt ggtatttttt tcatattgat
    10861 acgttaaatt atttatttta aacatcatta tcccctacta tgtgaaattt accatcatac
    10921 aattttatgt ctaatgatat acacatatca tcataccttg tcataagtct tttgtacagc
    10981 atacttccaa gaatacctaa ggatttatat gaagttttta aatttatata tccaaatctt
    11041 agctcttgtg acttgtatat ttctgaaaat tcttctaaaa atatgaatat aaacctatat
    11101 attaacattg ataactcgac aaaagtgtca ggtaaatgaa gttttttaaa aaagaatatt
    11161 aattgattaa aaggtgttgt aagtatacaa aaatacacac aagtcaaaca agacatcgct
    11221 ctaaataaca catgaataga catgtcaata gacgcctttg atattcctac attaaaacta
    11281 aaaaattcaa aactatataa taaatctgct ttattaaaag atatatttac aagagttatt
    11341 cctatactaa gaaataaaaa gtacattggt attctaagta attttaaata attttttaaa
    11401 tctattccag ccacacaaac aaccaaaata ctcattaaaa tcataattcc acttaaaata
    11461 aatatatttt gtattaccat agaagcaatc agaaaaatta ctcctatggc tacttttttg
    11521 tttggattta ctttactcaa tctatttgta tatgcatatt tatcaattat aagcatgatt
    11581 aacttctctt tcctttttga agacctaata tgtatcctat tacaccagcc cctaaagctg
    11641 cttgtgcaga gaataataaa ctttctattt ctccacttgg tggctcatat ggactgctaa
    11701 accatggttt gtaatttgga tttatcttag taatttcact ttcagcttga ccatctgctc
    11761 ctccatattc agcacctgag ttgacaagta atgggaatat aataagagct actactaata
    11821 aaagtaataa tatgttagtt tttgttttag cactcattag ctttaactcc tttatcatta
    11881 ttttctagta tgcttttttc tccgttttct gtaattaaat tatatacaat tacagtaagt
    11941 ataccttctg ctattgctat tggtatttga gtcataaaga aaattcctaa aaatttaatt
    12001 gctgaagcca ttaccccacc tgatgggtct gggaaagcca gtgctaattg tattgaagtt
    12061 attgtatatg tggctaagtc tcctattgct gctgcaagaa atactggaat agcattattt
    12121 ccatcttttt tctttaaagc cttaaatatt aggaatgata cgattggccc tattatcgcc
    12181 attgaaaaag cattagctcc taaagtagtt attcctccat gtgctaataa caatgcttgg
    12241 aatattaaaa ctatagttcc aagaacaaac attacgcttg gtccaaacat tattgctcca
    12301 agacctacac cagtaggatg tgaacaactt cctgttactg aaggtatttt tagtgctgat
    12361 aatacaaaca caaatgctcc acataaagct aataatactt tctttttagg gtcttgcttt
    12421 actattttac ctattgattt taatccgaat aagaaaaatg gtataaatat aactccccat
    12481 gctatagacc attttactgg taagtaacct tccattatat gcattgcatt tgatgtaact
    12541 ggagttaaaa tgattaacat aagtgcagct ataaccccta atttaatatt ctgtttcatc
    12601 ttagtatccc tctctccctt tctaataatt aaaacataat aatacatgtc tgatttattt
    12661 aataaaataa aaaagcctaa ctcgatggtt aggcttctaa ttttccacaa tctaaataca
    12721 aacacataaa acaaacatat ctgtataatt attataagaa actttctcca tccccgaaga
    12781 aattacttta atattttagg caggtctcct gacttagctt catcctactc ctcttccttc
    12841 ccatgagata taaaaaatat catcatagtg gctaacaaaa gtttcgtctg catcacagta
    12901 gcgggggctg taaaggaatt taaccttttt ccctattaat cttgcttaaa gaacctataa
    12961 tattatatat ttaattttta aattcttctt aaattatttt ctatataaat cattgtatac
    13021 cttttctgtg aaaatttcta cattttttat aaattttatt catttttata tttttatgta
    13081 tataaattct tttttgtaag tttattaatt tctaattatc ttctttaaat acattgaaac
    13141 tacatcagaa aatctagtta tatctcttga atatataaaa tcatttccat atattaatct
    13201 ttcagcttca agttctgatt cttttcctgt aaatactcct aatactaata tattttgctt
    13261 tctagctttt ctcacttcat tggctgtatc tctcaaacca actatacccc tataagcctt
    13321 ttctcctctt aatgttctct cactactttt tcctatcttt acatcatttg gtcttccatc
    13381 actgagaact atcaggattt tattttcttc atctctattt attagaccac tacatataga
    13441 ttttattgcc aaaccatctc tattattacc agcacaaaaa tattcaaata tattttcact
    13501 attttttata ctatcatcat aatctttaaa tctttttaat attgtatagt ctaaaaaact
    13561 agaaaatccc atcactctat ttggtatgcc aacttctgtt agagcatttg caattatgta
    13621 agcttgaatt gccacatttc cctgatttct actttgagag ccacttgcat ccaataatat
    13681 atcaataacg tatttccctt tttcattttc tatatcttta taaaatattt tattattatt
    13741 acttctacca actctccaag ctctattggc taatatagta ccacaatcag aatatactct
    13801 acttttagca ttttcttcta ttaaaattct tgatagactt tcttttaatc tctttatttg
    13861 ctgtctatac attctagcat gttctctaaa ttttcctaaa ttattttctt tttgtcttgt
    13921 tacatatttt agttgaaata cattattaca ctcacttcta agaactccat ctgtaaagtg
    13981 tattctacaa ccttcatgaa catttctaca attttgtgtc tcaatttttt taatttcacc
    14041 tttactcaaa taagtttttc cataataatg ttctattttt gaatatatct tatttgcagt
    14101 gtcttcatca acatatataa ctcggtctgc tgaattgcta catttagaat catcaaaatc
    14161 ccctacacct tctacaagca tggatgaaga tattgaatct atatcacttt caataatatt
    14221 ttcttcttca tcactataaa gttcttcata catgaaatca gcaaatgtat caaaatttac
    14281 ttctacactt tctacattat tttcatcaat aagactattt tcttctccat ttaatatgta
    14341 ttcaaaataa gttaaatata taacatctaa tgcttttaaa atctccataa tatcttgatt
    14401 ggtatctata tttcttatat cattaactat tcttctagtc atactatcta atgctgggtg
    14461 cttgtccata ctataaagta caaatgtgta tttaatttta tccataatat tatcattgtg
    14521 tattttggta aaacgtgaaa caatatcttt ataagcattt cttcttatgt cttctatccc
    14581 tggcctatct ttaatgacct tttcttcaac tattgtattt aatataactt gaattagacc
    14641 cagtataata tctttgttgt atccttttct tattctattt gtaagatatt ttttaactat
    14701 atcccaatct acatactttc ttctagcacc tgcaattatt gcaaaatata gacctatttc
    14761 ttttgaagag taatcttttt ctgatatatc tatactttca ttgtaatcac cagctattgt
    14821 ccatgataag ttattagctc tattttcaaa ttcataatca tcatatatcc atttcataat
    14881 ctcacctata ttaaatatga cttattggaa acacatctat actctcccat ttattaggta
    14941 ttctagtttt aattacatct ccaaccattt ctttctcata tacatcaaaa gtctttcctg
    15001 taagtcccat attaattgca agagttggtt ttaatcctct tcttatagtc ttaagagatg
    15061 ccataagacc acgtaaatca atagctttac tagatatctc tccattttga gacttcaatt
    15121 gtaaatctaa aaatattcct gcaaagtgta ttagtttttc ttcatcagca tctgaaaatt
    15181 cattttttaa aatcatcatt aacttatctt cttctatagg aggaatatct attaccataa
    15241 atctagatac cagtgcttca ttaagttctt ttgttcctgc atattcataa ttcatagtcc
    15301 caataaatct tgttgctgga tgtagattga ctctctcata cccaggtaca tcaattattc
    15361 ttctatagtc taaagctgaa tgtaccacaa ctatagcatc attttttgcc atattaattt
    15421 catcaaacac cccaaaacct ccattaatag cacactcata aactgagcct cttctaagtt
    15481 taacttcatt gtctataaat gtatctgtac ctataagtgt tgaactgtct gtatttatat
    15541 gaaatgatgt attccactga ggtctattaa atatttcccc tagattatca gcaagtaagt
    15601 tttttcccgt tgcctttggt cccgataata atatattttc ttcttctaaa atagctgcta
    15661 tacacataga caagatatct ttaccataaa aataagtttt agactttgtt actctgtatt
    15721 ctaaatcttt ttctaatcca taataatttc taaaatacag tacatcttca ataagttttt
    15781 catctacccc ttgcaccctt agattatcta ttatatccat atttttaccc cttttatata
    15841 aatagtattt gtttcatttc ttatcaccat tttagcataa aaggatataa gctaaaattg
    15901 attttttaat ctcccccatt ttaagtaaaa ccatgcacca ttttatcact acaaaattaa
    15961 gagtactact tactgatatt tcttgatttt attcgtctat acgtatataa tatatactga
    16021 taaattatga ggaaaggatg attgaaatat ggaatatatg tcttgcccag aagtagcaaa
    16081 aaaatggggt atttctgaaa gaagagtaca aaaactatgt gaagaaagtc gcataccagg
    16141 agtttcaaaa ctcgggtata tgtggctgat accaaagaac gcagaaaagc ctgttgatgg
    16201 tagaacaaaa agaagaaagg aagtacaata tgaatagcgt tttgattata gatgatgaca
    16261 aagaactttg tgctcttatg aaaaaatgtg ttgagcaaga aaatttatct gctattactg
    16321 cacatggtgg tgcagaaggt ctacatttag tcgataaaaa tagacacaca ctctctcttg
    16381 taattttgga cataatgatg ccagatatag acggttttca agttctgaaa aaaattagag
    16441 aaacaagtaa tattccagta attatgctta ctgctaaaaa tgacgaggat gataaagttt
    16501 ccggactacg tttaggtgct gacgattacc taacaaaacc gttcagcata aacgaactta
    16561 tggctcgtgt caattctctt attcgtcggt atactatgct aaaccctgct tttataacag
    16621 acacagattt cataataata aatggcatga ttattgacaa gacaaaccga attgtttctg
    16681 tcaataatat tcctgttcaa cttacaagca aagaatttga tttacttgct tttctggctt
    16741 ctaataaggg acgggtgttt accaaaaaac agatttatac acaagtatgg gaagaagaat
    16801 atgcttttga cgatagtaac atcatgtctt tcatcagtaa attgagaaaa aagattgaac
    16861 cagaccccaa ccatccattt tatattttga cagttcgtgg tgtcggttat cgttttaata
    16921 aggaggctta acatgaatac aagtgtctat ctgcttttga tattggctct tagcctgatt
    16981 attatagcgt accttgtttc tgtcctgcta cgtgtccgaa tacaacttac acttataaaa
    17041 gatgctttag aggatataaa aaatggaaac cttaatcgac gtattttaac agatgaaaac
    17101 gacattacaa aacaaatttg ctatgatatt aacgaaatag caatcaatag ccaatttcaa
    17161 cttattcagc aaaaacaatc agaacaagcc tacaaacagc taatgacaag tctctcccat
    17221 gatgtaaaaa ctccacttgc ttctttggtc ggttatttgg aagcagtaga aagtaaaatt
    17281 gttgtaggag aggaaaaaga cgagtatatc catgttgcgt ctaataaggc tcattactta
    17341 aagaattttg tagaaaatct atttgaatgg gtaaaattgg attctaagga acaagttttt
    17401 cattttgata tttttgactt gaatgaatta tcccgtaata ttatatctga ttggatacct
    17461 gttttagaaa gcagtcattt tgaatatgaa tttgatatac cagaaataga gtacttctta
    17521 cgtatagacg caaatgcata tacccgtatc attaataacc tattacaaaa tattattacc
    17581 catagtagtg gaaacaaaat gacattgaga atttttgaaa acaaagagca agctcaaatt
    17641 ataataacag ataatgggaa aggtatatct tcagacaatc tcccacatat ttttgaaagg
    17701 ttgtaccaat gcgaccattc acgagcttca aagggaaatg gtttaggctt ggcgattgca
    17761 aaggaactta ttaacgctca taagggaaat attaccgcca acagcactcc cggtatggga
    17821 acagaattta caatattgct tcctaaagcc ctgtaaaagt acgaggcttt cttactctaa
    17881 aacaagataa aagcaagatt atggcaaggt tttggcaagg ttcatgtttt ataattctaa
    17941 ttgtagttga ttttgacgtt gtatcaacta tcttttgtag aaacaaattt attaaaagtg
    18001 aggaaattat atatgaatga ttttgtgatt gaaacaaagc aacttacaaa aatttatggg
    18061 aatcaaacag tagttgacaa agtcaatctc catgtaaaaa aaggccgaat atatggtctg
    18121 ttaggacgca acggagctgg gaaaaccaca attatgaaaa tgattttagg attgacttca
    18181 atcacgtatg gcgaggtaga tgtatttgga gagaatatta agggacgtga aaaacaagta
    18241 tatccccgta tcggtgcaat tatcgaaacg ccaggatttt atcctaatct gacaggaacg
    18301 gagaacttgg agatttttgc aaaactgcgt ggtacagccg cccctaattc tgtaaaaaga
    18361 gcattggaaa ttgtaggctt accttataaa aataaaaagc tgtttagtaa atattcactt
    18421 ggcatgaaac agcgacttgg tattgccaac gctatcctgc atgacccaga actgttagtt
    18481 ttagatgagc caaccaatgg tcttgaccct attggtattg cggagatgag aaagtttatt
    18541 agggacttga gcgttgagca tggaaagaca attcttattt ccagtcatat tctttcagaa
    18601 atctcattgt tggctgatga tattggaatt atcgaccacg gtgttctttt ggaagaaagt
    18661 agtatgagtg aactagaaaa gaaaaacagt aaatatatcc tgctacaagt ttcagatatt
    18721 ccgaagacat cacttatttt agagcgtcaa tttaacacga aggattattc cgttcaagat
    18781 gactacacgt tacaccttta taacactaat ctggatatgg gtgaaatcaa taaagcactt
    18841 gtaatgcaga atgtaactgt tattagttct caactttgta atgatacttt agaggactac
    18901 tttaaaaaaa tcacaggagg agagggcatt gcttaaactt attcaaacag aatttcttaa
    18961 actgcgtcgt aggaaactta tttggctgat gttgttgtct gctctcatta tgccgttttt
    19021 cgcactacta tacttcaatt attttggtaa aacaggtgtt gagccaataa agttttataa
    19081 atggtctgca tttggttata cactttggat tattttgcct gttgttttgg gtatattttg
    19141 caccatgctt atacacgaag aaaaccagta tgatatgctc aaacagcttt ggattgtacc
    19201 tattagtaaa atgggatact tttttagtaa atttttcgtt gttttgattt actctatttg
    19261 ttttatgctg attacagccg ttgcttctgt gttatttagt gtactttctg gatatgtcgt
    19321 atttagctgg gcaagcattt tatatttgtt gaaaaaatgt ttagaaattg gtgtaatcac
    19381 tgcttttgta atgttgccga ttttggcaat cgctacatct caaaaaggat acattctccc
    19441 aatttgtatc acattggtat atgccttttc cggttttgtt ataatgacaa taaatatgta
    19501 tttacaccca ttatccagta tgggagttat tatcatgaga aataaagaca ttccaggtct
    19561 tatattttca caggaaatta atgtcccatt agcatttctt tgtatttgta tttggagtat
    19621 tgtatcagta ttgtttgcaa atattgcact aggaagaaga aagtgaggtg tagataatgt
    19681 ggaaattact ttgggctgaa tgtcaaaaaa ttcgtcgttc aaaaattgtt tggattacag
    19741 tttttgcatc cattatgata gcagtcatag tttttgcagg ggggcaggat gtatataatg
    19801 acccagattt acattatggc ttaaagagcg tttatgacgg ttcacggtat atagacaatg
    19861 caggttggta tatggacgca gtacaacctt ggtcaacttt ttttgttctt cctgctgtca
    19921 ttgccctatt aggaagctat attatttgtc gtgaagaaga ggaggacact attaaatccc
    19981 tgcgtcttat tcccataaat gaaacaaatt taaccatagc aaaaatgatt attactttta
    20041 tattcagtat acttctttat ttgttactct ttactataac atttttgact gaatccgttt
    20101 tacatttttc cgatttatcg acaaaattgg ttttaagttg catgaaagag tattttcttg
    20161 atggcatagg tgtattcttt gcaatttctc ccattattgc cttggtatcg cgcatgaaaa
    20221 aaggatattg gcttgcatta gtattcacag aagtttattc tattgctgga ctatttgcgg
    20281 gtatgtcaaa tgtcttacaa accttttttc ctattgcggc aatatttaat atttctggat
    20341 actatataac tactggagaa aaaattatgg ggagtatcat gagtttatta ctttgtgcct
    20401 gcctttctgc atttatactt aaagggctaa aacacaatga aaaaaattga aataggtata
    20461 tcaaaatgaa aaagataaaa aaactgatta ttctaattgt attcttgttt ctttttggca
    20521 tgttacactg ttatactgaa tggaaattca acaataaccc acctaaaggg gtaatagaaa
    20581 gaataaatga gtggactgat aagattggac tggattagta acttatgtta attatagtga
    20641 atgtaatatt agcaagttat tgtttcgtat tttaatacta taactttaaa tatttggttt
    20701 taatcttcca aacgaatata aaaaaactgt cacagaggca acatattttt gaatatttat
    20761 aaagtggtag ttttgatttt caaagctacc gccttttctt ctatataagc aaacttatcc
    20821 tcaacaaagt gtaaaacatg gtgcatttta agaaaaaagt accacagaca caagcaataa
    20881 aagaaacgcc gagaacctac aaaaacgtag tgcttatgca gatttacgac gccttctatt
    20941 ttctcaaccg tcttaatgac cttgtacaaa agaaattttt ctaatatttt ttataatctt
    21001 atcttgtgat gttttttatg tataaatgac ttaataacaa atccaataaa aattatggat
    21061 attggtataa ttagaacgag gaatttataa tcattataat gtgacattat tcttacccaa
    21121 ctctcagaaa aaatatatcc tatactgatt aatgaagtat tccatatggt tattcccacg
    21181 atagatgata ttacaaaagt tataatattt tgacctgcta tacctgctat aaaagatatg
    21241 tatgttctac ataaagggat taatctacat acacaaacag aaatagaaga gtatttatta
    21301 aaataatctt gagatgcaaa tattcctttc tttgcctttg gacatatctc tattatttta
    21361 tttatgatag atttacctcc ccaatttccc actgtataac aaaatatcga accaagtata
    21421 cctgcaatta tacttaaaat taaaattgtc agaaatccaa aatgatttct tgcagcaatt
    21481 gctccacata aaggtaaaac aacttcgcta ggtaatggaa aacaagcata ctcaatcata
    21541 attaatacaa atacagagat taatccatat tgtaaaataa aactattgat tacagacact
    21601 tacttatcta tctcctttct tatttaaagg ttttaagggt acatgttcta aggattctca
    21661 ccctatattt aaagaatcaa tctctttaaa ctattatatg tatttacaca aagcatttat
    21721 aacatacttt aaaaatagta ccttaaaata agaaacttaa taaataaaaa aagattacgt
    21781 ggctacgtcc tactctccca ggcagtttcc caccaagtac catcagcgct agagagctta
    21841 acttctgtgt tcggaatggg aacaggtgta tcctctctgc tattgtaacc acataatctt
    21901 tatgcttaat atttc
//
LOCUS       DAMJVG010000064        21721 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.064, whole genome shotgun sequence.
ACCESSION   DAMJVG010000064 DAMJVG010000000
VERSION     DAMJVG010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21721)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21721)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21721
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.064"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            66..1373
                     /locus_tag="PC512_002652"
     CDS             66..1373
                     /locus_tag="PC512_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442386.1"
                     /translation="MKEIADAITSEYLSYGINEDISIYEGRFCIYLDKKYRCNGKIYY
                     KMTPPISISFKADIGCVEEIDNEDDNLALDYDNAILEVHGYKIISITINTLSEFSVEG
                     YINDDCIKSKNSYVEYVDFNIINLDKIPGKLIKYNDKVYAGRIEFDINDYVVTIDKRY
                     DYRKELKSELKSKSGAIITHIGRIRRKDGRIFRTNNTINLLDRISTALSFMCGRYVGF
                     CLAKGYRSGNEVYRIWNENQISPFRYVPTWSDTLSNYYNMEKYISLMCKKLEDFYYGS
                     AIKSVVDWYIESLGSATMENNIISVQIALETLSYVILVEQNKILTDEVFDCNLASKNI
                     RLLLDTCKIPYGKHELNIFDNIIKNKFDDGVDLVIYLRNSIVHPSRKTHRAVLEVEDI
                     WNIISIGTRYIELVLLFILGYRGEYSNRLVERCYGEVEVVPWN"
     misc_binding    1459..1721
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1847..2650
                     /locus_tag="PC512_002653"
     CDS             1847..2650
                     /locus_tag="PC512_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF2442387.1"
                     /translation="MKNILKKVGIFTIMLGLLGGVVGCSKPDNEKDKDASKESKKEVV
                     VGFDNTFVPMGFLDEKGDTVGFDVDLAKETFKRLGMEVKFQPIDWSMKETELNDSKTV
                     DVLWNGYSITDERKKIVSYTEPYLQNKQIIVTLSDSKINSKADLKDKEVGTQQGSTAL
                     DAVEKDKDFMNSLKGGAPVLYDTYDKALRDLEIGRTSAVVGDEVLIRYYMGQKGEDKY
                     KVLKDDFGLEDYVVATSKENPELCEKINETLKEMKKDGTFDKIYDKWFK"
     gene            2688..3299
                     /locus_tag="PC512_002654"
     CDS             2688..3299
                     /locus_tag="PC512_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDF2442388.1"
                     /translation="MLQGLEIVIAMFCITLIVSIPLGIGVAFLRLSKNKLVSGITQCY
                     ILIMRGTPLLLQMIVIFYGLPLLGIVFDRFTAGVVAFFLNYAAYFAEIFRGGIQSIDR
                     GQYEASKVLGFDKFTMYKRVIFPQVFKRILAPISNEVITLVKDTSLVYILGLNDILRI
                     SQIAMNREASLLPLFEAGAIYLIFVAILTKGFELLEKKYSYYR"
     gene            3331..4002
                     /locus_tag="PC512_002655"
     CDS             3331..4002
                     /locus_tag="PC512_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HDF2442389.1"
                     /translation="MLKIKNLNKSFKKNRVLKDISFELEEGQIGVLLGKSGAGKTTIL
                     RCINGLEEFDSGEIIIDNEVIKNKRDMAKIRGKIGMVFQNFNLFPHMTVLENIIESPV
                     NVFKVPRKEAEERARELLRLVDLEDKLNSYPFELSGGQQQRVAIARSCALMPKVLCFD
                     EPTSALDIDTIQRVVNIMNRLKDKGMTILIITHDVVFSNNVADKIISIKDGIVENVQI
                     KEKIV"
     gene            4300..4662
                     /locus_tag="PC512_002656"
     CDS             4300..4662
                     /locus_tag="PC512_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HDF2442390.1"
                     /translation="MIKLYGYTKCSTVKKAKNWLKENNLEFEDIDMVQNPPSKEELKS
                     IYKTSGYDIKKFFNTSGMKYRELGLKDIVKTESDDKLLEILVSDGMLIKRPLLLDGKN
                     VLLGFKEDVWKSTLLKED"
     gene            5098..5799
                     /locus_tag="PC512_002657"
     CDS             5098..5799
                     /locus_tag="PC512_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4253 domain-containing protein"
                     /protein_id="HDF2442391.1"
                     /translation="MSIEDLYDFECVPLNNEIDIDVLFEKMIEDGKEKEYTPIIVIDE
                     KVGLLRKNIDMITKEYGSLENYREYCLTKYNEIDVNQFFDFRKSEISELLKELIDLED
                     DFYDYKHFRPIMNIDIFHEYNKVYIAKIPTIKPYEVFAYIPIGGFNDCPRDEEHIAIA
                     KYWYEKHGIFPIAIGCDTVQYSVKNLTKDGKKFDDLCIELVFYCEDIIIQGYETLKAL
                     KDVLKRSTIVLFWWD"
     gene            6069..6887
                     /gene="larE"
                     /locus_tag="PC512_002658"
     CDS             6069..6887
                     /gene="larE"
                     /locus_tag="PC512_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent sacrificial sulfur transferase
                     LarE"
                     /protein_id="HDF2442392.1"
                     /translation="MEVNFVKEKEKLDKLKKMLLELGSVVVAYSGGVDSNFLLKVAKD
                     TLGENVIAVTIHAMMHSSREIEEAKQYTQNFGVKHIILNIENFDLKEFKENGVDRCYH
                     CKKYIFSKIKEVAKEHNIKYIVDGTNIDDLGDYRPGLKALSELGVISPLKDSSLKKEE
                     IRSLSKTLGLNTFNKPSFACLASRIPYGVEITDENLRIVEKSEEYLSNLGFSQFRVRM
                     HGDIARIEVGQEELGKFFENNNFNKVDTKLKIFGFKYVTLDMSGYKMGSMNLNV"
     gene            6942..8090
                     /locus_tag="PC512_002659"
     CDS             6942..8090
                     /locus_tag="PC512_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HDF2442393.1"
                     /translation="MKNYTLISPCFFGMEKMLAREITNLGYEIIKTEDGRITYKTDEF
                     GIAKSNMWLRCAERVHLKIAEFEAKSFDELFENTKRINWSRYIPYGAQFPISKASSIK
                     SKLYSTPDVQAIVKKAIVESLKKSYLEDGLLKEDKEKYPIFVFIHKDKVTISIDTTGD
                     ALHKRGYREKANKAPIRETLAAGLIYLTPWKAGRVLVDPMCGSGTILIEAAMIGINMA
                     PGLNREFISEKWRTLDKKIWWDVRKDAFNKIDNESKFKIYGYDIDEESIDIARENAEI
                     AGVDEYIEFNVGDATQFKSEDEFGFIITNPPYGERLEDKDSVKQLYKELGYAFRKLKN
                     WSYYLITSYEDFEYEFGQKADKKRKLYNGMLKTNFFQYPGPKPPRNNK"
     gene            8226..9614
                     /locus_tag="PC512_002660"
     CDS             8226..9614
                     /locus_tag="PC512_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDF2442394.1"
                     /translation="MKVLKLITVVALMMLFVTGCNIKTESPEQLAKIPDYDDTKKVLY
                     DGIDQLLKPDSSMILPSNTKEVGKINKVDLNSDGIDELVVFEQKEDLSNNVSQVGFVT
                     LSYNGEKYVLGDHFLENGESIEYANFYDLDSDGYKEVILLVKSKDKTNMHIYKVVDNE
                     ITKIYDLDASWLQNKEDFNDMKVKIGYIDGDDKLDILMLHLNNKTNEMFASVANFDGK
                     MKIKDSVKFENVKNLSELYITLGNVASSVGNSSAAIKGIVLDIPILKDNNYITQILYM
                     KDGKINKAFSDYDKTITKSYYIPVDDIDKDKIIEIPIVAGSTGNNKNTYSSKSSATIS
                     WYRWNGKEGADSSLIFTSQIYYNYKYNFKLFIPNNLFDKILVEQEFVGEKAVFKFYYF
                     DYSDRKNLFNIVVESKNKLEDRKNTGTQNSIVLQESDEYTFLLVVNNANEMDKLDMTI
                     DALKEYFSLIYG"
     gene            9643..10341
                     /locus_tag="PC512_002661"
     CDS             9643..10341
                     /locus_tag="PC512_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2442395.1"
                     /translation="MKEKILILEDEIGIRSFVSINLKREGYEIVEAGTGREAIEKMTT
                     EKDITIALLDVMLPDISGIEVCKFIRENFDQVGIIMLTAKAQEDDKIEGFISGADDYI
                     IKPFSIKELLVRVSALLRRVAKDDSSVKSSEIVSPPFILDIDKRKLFKNGKEIELTPT
                     EFSIVKYLISNAKQSLSRDQILDEVWGTNYLYDFKIVDVNIRRIRNKIEDDPSKPKYI
                     QTIWGYGYCFRKEE"
     gene            10344..11777
                     /locus_tag="PC512_002662"
     CDS             10344..11777
                     /locus_tag="PC512_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2442396.1"
                     /translation="MLHFEGLRKKVIKNYFIIIIIMVTLFEGLFMFYIQNYYYDSVKQ
                     LLESEIKYADEYNAITMETTSFEKKVKNIFDKQPLTKNSEFGISIIDKDKNIILDQYG
                     FKSKEKANYEDVNNALKDIKTKNLTPYTYRIPDTGEHVMSISLPLKVNNIIEGVVRYT
                     VSLDAIDNAILKQATWLILAGIFILIIAILISLKFAETLIKPLRELKKFANELAVGNY
                     NIKLEKMKIVDDEIGDLAQTFEHMAHEIDKSEKLKEEFISSVSHELRTPLTSIKGWSE
                     TLGYESITREELDLGLGIIQDETERLIKLVEELLDFSRLSSDRIKLHVDIVDVEGLIV
                     GVVNQLKVKAAEKDISLLFEFENEFIENIQGDKNRLRQVLINLIQNSFKFTSQGGYIK
                     VVASQDEEITTISVEDNGSGIEKQNLNKVLDKFFQEDYNKAGSGLGLAISNEIVKLHG
                     GRMKIESEKNVGTKITFNIKNKFAKQA"
     gene            11799..12536
                     /gene="truA"
                     /locus_tag="PC512_002663"
     CDS             11799..12536
                     /gene="truA"
                     /locus_tag="PC512_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011010156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HDF2442397.1"
                     /translation="MRNIKMIVAYDGSRYKGYQKLGDNNMTIQEKLENVLSKMTNETV
                     EIIGSGRTDMGAHARGQVVNFRTNCMDSLDKIQKYLYEYLPEDIVVKTVEEVDERFHS
                     RYNVKSKTYMYKIDNNKYHNPFIRKYATHVSKKLDLDRMRKASEYLVGEHDFTSFASS
                     KSKKKSNVREIYSINIKEDDNVIEIYVEGNGFLYNMVRIIVGALIDVGLKRRAPQDIK
                     YMLESKDRCQSSDTAPAKGLCLWKVTY"
     misc_binding    12647..12854
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            13107..14306
                     /locus_tag="PC512_002664"
     CDS             13107..14306
                     /locus_tag="PC512_002664"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HDF2442398.1"
                     /translation="MKEKVVLAYSGGLDTSIIIPWLKENYEDIDVIAVCGNVGQEDKM
                     EDVYEKALQSGASKAYVDDISEEFVTETIFKAVKAEAKYEGKYLLGTSLARPIIAKKL
                     VEVAHKEGAKYICHGCTGKGNDQVRFEATIAALDPTIKVIAPWRIWDIKSREDAIDYA
                     EKHNIKVTATKAKIYSVDANLWHVSTEGGDIEHLENEHKKDVYKQCVDPEDACDVAEY
                     VEVYFEKGVPKKVNGEELSPVALIHKLNELGCKHGIGVIDIVENRLVGMKSRGIYETP
                     GGTILYEAHNILESATLDKDTLHFKQMVSYKYGELIYNGLWYCKLRESIDAFMEQTQD
                     NVTGTVKVKLYKGNIKPAGIFTENALYDEGISSFGNSELYDHKDAEGFINLFTLPLKI
                     RAMKAGK"
     gene            14553..15599
                     /locus_tag="PC512_002665"
     CDS             14553..15599
                     /locus_tag="PC512_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4872 domain-containing protein"
                     /protein_id="HDF2442399.1"
                     /translation="MRKIIEIKHHSHDYECMWNGIEDLYINKTGEYLPNDFFFLLSGF
                     GSFCYMKTNKADLKRMVALGDGRTKQMYKFLAPIVGFEYKHHEFKKYEQALKKAKSEI
                     DDGYPVILGALDMYYLPYYKKLYHKEHIPFHYILMVGYDDEGIYLYDCGRTELLHLSY
                     DKLRESMNCNSPGLSKENTICTIRMNTSKNKYNIAREAIAIKRDMFLNPPKGFLGYKG
                     FEKFIKELPQWNTELDKDDYDKILTNMVMFFGTVPTIPNAIKGIKEPDTVQFKGGFDK
                     MSRMLNSIGEEYKNNSFIQVADIFDKTAIIIEKISNIIIDYLTQTCDDTEQLPLLFSE
                     VLEHMKTGYLILDV"
     gene            15707..16870
                     /locus_tag="PC512_002666"
     CDS             15707..16870
                     /locus_tag="PC512_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2442400.1"
                     /translation="MRTVKQVSDLTGISVRALHYYDEIGLLKPNKITDAGYRLYDDES
                     IKTLQQILFFKEIDIPLREVKEIMSSQYFDKVEALKNQKKLLILKRKRLDELIELINQ
                     TLRGEGNIDFKEFDMSEYFNVLEEFKREHRNKVIKIYGSVEKYNEYIERVKSNEEKIA
                     KMAIKQYGTIEKFAKAIKTNFSSDILNLGEKFDRYKNDCLKEKHPKLKELYRKLVEDL
                     SRNPSSTDLQEIAKAITDISKKDYEIFSMDTGDDNWYYMVQNYLVNPMWIEEVDKKYG
                     SGAGKFIGQVLKTYLRDRKPKINTLYEKLVEDLSRDCSSREVQSIVEEIDNEMKRSNE
                     FYKIDNGERYFDYMSELYLQDSNYIKVTDKNYGDGASKFIGEAFKIYFDNNNC"
     gene            complement(16959..17339)
                     /locus_tag="PC512_002667"
     CDS             complement(16959..17339)
                     /locus_tag="PC512_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4363 family protein"
                     /protein_id="HDF2442401.1"
                     /translation="MKSTTFVILWTILFVLFGFYVNNKLYDFTEGYKDNISVLEKSIE
                     NEDWEKAQKEADSISTSWNKEKNHWYKVLNHEYFDEIGLRFNILDKAIYTENKLKSLE
                     EVESIKTYLGNIIESVKFDVNYIF"
     gene            complement(17342..18001)
                     /locus_tag="PC512_002668"
     CDS             complement(17342..18001)
                     /locus_tag="PC512_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HDF2442402.1"
                     /translation="MTVVLIRSIILYITVLIALRVMGKGEIAEMNCFDLVITLLIAEV
                     ASVPMENNNIPIINGVAAISGLVIMQTLISFLSLKSRKLSSFLSGKPSVLIDKGKIVY
                     KELKKERISIDELLEQLRIQGYFNLKDVQYAILETDGNLSVVPASSYNSTPPRAFNHL
                     PIPLILDGRIINKNLDIAQKDTNWLMGILKSNHIETFKDVLICVLDENDKIFIQNKKG
                     D"
     gene            complement(18107..19081)
                     /locus_tag="PC512_002669"
     CDS             complement(18107..19081)
                     /locus_tag="PC512_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HDF2442403.1"
                     /translation="MKYKLFIDFEFNILDDNKNKPKEYNGAELISIGGVLVDNEFNTI
                     DNYYSLVKPKYNKILSNKCKNLTKLNQLDINNAPNLLYVMDDFYKWFCKFDDVTIYNW
                     GDFDITGLLTSFRVYKYTGKCLELFNMMIDIQPFISQHITYNNRILSKQISLLNMKKI
                     FSVEGDIKHNSLSDAVDLMNVCKCFFFNSPKNIDILEELYNKLPALKTPLYYIPYFED
                     ENFELKFDRTPEDIIIYLKQILTILNISKKEIYFKKRSVLVNNSKIINFKNLSSSFKL
                     IKLNEFEEYPDFILKLGDKKSFVESVIKINKSNRKSIKNLILKLSKKP"
     gene            complement(19121..19468)
                     /locus_tag="PC512_002670"
     CDS             complement(19121..19468)
                     /locus_tag="PC512_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442404.1"
                     /translation="MLNLKEIREEIIKKYIGDSLISELTEELKNILITDLQSNPFKSN
                     IELSIIPANIEIFKKIENILIDSKVNLKMGWERILINYILKDLFELNYEINKSCNEPL
                     MFRVIISIDSYDA"
     gene            complement(19686..20642)
                     /locus_tag="PC512_002671"
     CDS             complement(19686..20642)
                     /locus_tag="PC512_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HDF2442405.1"
                     /translation="MKKILITGALGQIGSELTIKLRNEYGEQNVIASSRRVKEGNPVC
                     ESGIFEILDVTDKNRFFEIAKKYDVDTIIHLASLLSAVAESKPLEAWNLNMNGLINGL
                     EIAKELDCKFFTPSSIAAFGENSPKNMTPQDTLQRPNTMYGVTKVSGELLCDYYHSKF
                     GVDTRGVRFPGLISYVTPPGGGTTDYAVDIYYEALKNKRYKSYIAEGTKMDMMYMPDA
                     LQSIVDLIEAPADKLIHRNAFNITAMSFSPEEIADSIKKYIPDFVIEYDVDPVRQSIA
                     DSWPNSLDSSSAVKEWNFKFSYDLDKMTKDMLEKLSEKGIGK"
     gene            21085..21453
                     /locus_tag="PC512_002672"
     CDS             21085..21453
                     /locus_tag="PC512_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C-GCAxxG-C-C family protein"
                     /protein_id="HDF2442406.1"
                     /translation="MTRPSIYHSQGYTCAEALIKSYNEEHNTDIPISIGSGMGVGMNV
                     GSVCGAVNAAVVIIGYLNGRNSNLDENIARKYSRELLNRVRNKYSSEICVSLKKNKVT
                     CEEIINFTYDALNDMLKNQK"
BASE COUNT         8601 a         2214 c         3594 g         7312 t
ORIGIN      
        1 taaattatat aaattaaatt atataatata ttgagtttta cataaaagca aaggtgggaa
       61 taaaaatgaa agaaattgct gatgctataa catcagagta tttaagctat ggtatcaatg
      121 aagatattag tatctatgaa ggtagatttt gcatatattt agataaaaaa tatagatgta
      181 atgggaaaat ttattataaa atgacacctc caatatctat aagttttaaa gcagacatag
      241 gttgtgttga agagatagac aatgaagatg acaatttagc tttagattat gataatgcta
      301 ttcttgaagt tcatggatat aaaattattt ctataacaat aaatacttta agtgaattta
      361 gtgtagaagg ttatatcaat gatgactgca taaaatctaa gaactcctat gttgaatatg
      421 tagattttaa tataataaac ttagataaaa tacctggaaa actcattaaa tacaatgata
      481 aggtatacgc aggtagaatt gaatttgata taaatgatta tgttgtaact atagacaagc
      541 gatatgatta tagaaaagaa ttaaaatcag aattaaagtc taaatctgga gcaataataa
      601 ctcatatagg taggattaga agaaaagatg gtagaatttt tagaacaaat aatacaataa
      661 atcttttaga taggatatca acagctttga gttttatgtg tggaagatat gtagggtttt
      721 gtttggccaa agggtataga agtggtaatg aagtttatag aatatggaat gaaaatcaaa
      781 tatctccttt tagatatgta ccaacatggt cagatacact ttcaaattat tataatatgg
      841 aaaaatatat aagccttatg tgtaaaaagc tagaagattt ttattatggt tctgctataa
      901 agagtgttgt tgattggtac atagaatctc ttggaagtgc taccatggaa aacaatataa
      961 tatctgtaca aattgcactt gaaactttgt catatgtaat tctagtggaa caaaataaga
     1021 tacttacaga tgaagtattt gactgtaatt tggcatctaa aaatataaga ctcttacttg
     1081 atacatgtaa gataccatat ggtaaacatg aattaaatat atttgataat ataataaaaa
     1141 ataaatttga tgatggagtg gatttagtta tttatttaag aaatagcata gttcatccaa
     1201 gtagaaagac tcatagagct gtgttagagg ttgaagatat ttggaatata atttcaatag
     1261 gaacgagata tattgaactt gttttactct ttattttagg ttatagagga gaatattcaa
     1321 acagattagt agaaagatgt tatggtgaag tggaagttgt accttggaac tagattttta
     1381 tatttatttt aaaatatata ttgacatata ttgccttatg ctataaaatc aatatcataa
     1441 taataattca gaataacatt aaatgctaag aaaagaaata gtaaaagtag ttaatcttaa
     1501 acagagagtt tccgattggt gagaggagca atagatttta ctttgaacac atctttgagc
     1561 aggactctga aagagtagaa atactttatt aggagatttc cggaatcctt gcacccgtta
     1621 tagtgctaga gtataataat tttattgtac ttaaagaggt tagtgtcgtg aggcattaat
     1681 gaacagaggt ggaaccacga gagttaactc ccgtcctcta gcagaagcta gaggcgggag
     1741 ttttttaata taatttttta agcgcgcaga gaattatatt gcaatagata cactttttaa
     1801 aaaataatca aaatatttta aaaattaaaa ggcgagggag aatattatga aaaatatatt
     1861 aaaaaaagta ggaatattta caattatgtt aggtttatta ggtggagttg taggttgttc
     1921 aaaaccagat aatgaaaaag ataaggatgc ttcaaaggaa tctaaaaaag aagtagttgt
     1981 agggtttgat aatacgtttg taccaatggg atttttagat gaaaagggag atacagtagg
     2041 atttgacgta gacttagcta aagaaacatt taaaagactt ggaatggaag ttaagtttca
     2101 gcctatagat tggtcaatga aagaaactga attaaatgat tcaaaaactg tagatgtatt
     2161 atggaatgga tattctataa cagacgaaag aaagaaaata gtatcatata cagaaccata
     2221 tttacaaaat aagcagataa tagttactct aagtgactca aaaataaatt caaaagctga
     2281 tttaaaagat aaagaagttg gaacacaaca aggttcaaca gcacttgatg cagtggaaaa
     2341 ggataaagat tttatgaata gcttaaaagg tggagcacca gttctttatg atacttatga
     2401 taaagcactt agagatttag agataggtag aactagtgca gttgttggtg atgaagtttt
     2461 aattagatac tatatgggac aaaagggtga agacaaatac aaggtattaa aagacgattt
     2521 tggattagaa gattatgttg tagcaacttc taaagaaaat ccagaacttt gtgagaaaat
     2581 aaatgaaaca ttaaaagaaa tgaaaaaaga tggaactttt gacaagattt atgataagtg
     2641 gtttaaatag aagataagtt agctgttaag aagggggcac taaaggcatg ttacaaggtt
     2701 tagagatagt tatagcaatg ttttgtataa cattgatagt atcaattcca ttggggattg
     2761 gagttgcatt tttaagatta tcaaagaata aattagtaag tggtattaca caatgttata
     2821 tattgataat gagaggtaca cctttacttt tgcaaatgat agtcatattt tacggattac
     2881 ctcttttagg aattgtattt gacagattta cagctggagt agtagctttc ttcttaaatt
     2941 atgcagcata ttttgcagaa atatttagag gtggaataca gtcaatcgat agaggacaat
     3001 atgaagcttc aaaagtacta ggatttgata agtttactat gtataagaga gtaatctttc
     3061 cacaagtttt taaaagaata ctagcaccta tttcaaatga agtaatcaca ttagtaaaag
     3121 atacatcttt agtatatata ttaggattaa atgatatttt aagaatatct caaatagcaa
     3181 tgaacaggga agcaagtctg ttaccattat ttgaggcagg agcgatatat cttatatttg
     3241 tagctatact tactaaggga tttgaattac ttgaaaaaaa atattcttat tatagataaa
     3301 gttacaatat tataggagga ggttttttat atgttgaaaa tcaaaaactt aaataaatca
     3361 tttaaaaaaa atagagtact taaagatatt tcttttgagt tagaagaagg tcagattgga
     3421 gttttacttg gtaagtctgg tgcaggaaag accacaatat taaggtgtat aaatggtctt
     3481 gaagaatttg atagtggaga gattataata gataatgagg taataaaaaa taagagagat
     3541 atggcaaaaa tacgaggaaa aataggtatg gtttttcaaa atttcaactt atttcctcat
     3601 atgacagtcc ttgaaaatat aattgaatcc ccagttaatg tttttaaagt tcctagaaaa
     3661 gaggctgaag agagggctag agaactttta agattagttg atttagaaga taaattaaat
     3721 tcttatccat ttgaattgtc aggaggacag caacagagag ttgctatagc taggtcatgt
     3781 gcattgatgc caaaagtcct ttgttttgat gaacctactt ctgcacttga tattgatact
     3841 attcaaagag tagtcaatat aatgaacaga cttaaagaca aaggtatgac aatattaata
     3901 attacacatg atgttgtctt ctcaaataat gttgcagata aaattataag tataaaagat
     3961 ggtatagtag aaaatgttca aataaaagaa aaaattgttt agagttttat aaatataaac
     4021 tagggtagaa ttttataata taaataaagg gcaagtaaaa tcaaatatac tatgcccttt
     4081 tgttatctca aaatttaatc ttatatttta tgtttaagtt acattataat ttataataaa
     4141 aataaaagga ctatttaaat atataatgtg aataatgttt aataatttga aatatgataa
     4201 ttttttatgt tgaaagctta taatgattat gatataaatt ggttatagta tacaatttat
     4261 gggtataaca ataaaaaatt agaaaggaat ttttataaaa tgattaaatt atatggatat
     4321 acaaaatgct ctactgttaa aaaagctaaa aattggctta aggaaaataa tttagaattt
     4381 gaagatatag atatggttca aaaccctcct agtaaagagg agttaaaatc aatttataag
     4441 actagtggat atgatataaa gaaatttttt aatacaagtg gtatgaaata tagagaattg
     4501 ggtcttaaag atattgtaaa aactgaatct gatgataaac ttttagaaat attggtaagt
     4561 gatggtatgc ttattaaaag accattactt ttggatggta aaaatgtatt attgggtttt
     4621 aaagaagatg tatggaaaag tactttgcta aaagaagatt aggaagagat aggtgtgttg
     4681 attaaaatta ttaattaata cacctataaa tttatgtatt aaatctaatc tttataaata
     4741 ttaattagca aattcaaatc aaaaaaattc atatcaacaa acatattact tcttattaca
     4801 aattatatca tatgttttat attaaaatat tataatatta caacgaattg ttacaaaatt
     4861 acttattatt aaccatgaac atttgttttg tgctatcata tttatataag ggaattgtca
     4921 taaaaaatat cttgttcata cagttttata tagaaaaaag aaatgaatct tttctttata
     4981 taagtatatt ttgtaaattg cctctatatt tatagtttaa ataatagtgg tattaaaaat
     5041 ctgacaacaa aaataaaact ttcaaaaaat taaatctaaa aagaatagga gataaatatg
     5101 agtattgaag atttatatga ttttgaatgt gttcctttga acaatgagat tgatattgat
     5161 gttttatttg aaaagatgat agaagatgga aaagaaaaag aatatacacc aattatagtc
     5221 attgatgaaa aagtagggct attaagaaaa aatatagata tgattactaa agagtatggt
     5281 tctcttgaaa actatagaga gtattgttta acaaaatata atgaaattga tgtaaatcaa
     5341 ttttttgatt ttaggaagag tgagatttca gaattattaa aggagctaat tgatttagaa
     5401 gatgattttt atgattataa acattttaga cccattatga atatagatat atttcatgaa
     5461 tataacaaag tttacatagc taaaattcca acaattaaac catatgaagt atttgcatac
     5521 atacctattg gcggatttaa tgattgtcct agagatgaag aacatatagc tattgcaaaa
     5581 tattggtatg aaaagcatgg aatctttcca atcgcaattg gatgtgatac agttcaatat
     5641 tctgtaaaaa atttaactaa agatggtaaa aaatttgatg acttatgtat tgaattagta
     5701 ttttattgtg aggatattat tatacaaggg tatgaaacct taaaggctct taaggatgta
     5761 ttaaaacgct ctacaatagt gcttttttgg tgggattgat attctatcat ttagatagta
     5821 ttaaattgtt agtcaccaag aatccacttg ctttagttat agggagtgtg tcaaactagg
     5881 tttttataca cagtgtagca tagtaatatg tttaaattac aaaggttaaa aaaatacttt
     5941 aatattttta atattataat taatagattt aaggtaatta taatttataa aataaatact
     6001 ttatatgtta taatcattaa gaatgtaaaa aaataatata tagttttata gttcatattt
     6061 ttccagatat ggaggtaaat tttgtgaagg aaaaagaaaa attagataaa ttaaaaaaaa
     6121 tgttacttga attaggcagt gttgtagttg cttattctgg tggagtagat agtaattttt
     6181 tgcttaaggt cgcaaaagat acattaggtg aaaatgttat agctgtgact attcatgcaa
     6241 tgatgcattc aagtagggaa attgaagagg ctaaacaata tactcaaaat tttggtgtta
     6301 aacatatcat attaaatata gaaaactttg atttaaaaga atttaaagaa aatggtgttg
     6361 atagatgtta tcattgtaaa aaatatatat tctctaaaat aaaagaggta gcaaaagaac
     6421 ataatataaa gtacatagta gatggaacaa atatagatga tttaggagac tatagacctg
     6481 ggcttaaggc attgagtgaa ttaggagtaa ttagtccatt aaaagatagt agtttaaaaa
     6541 aagaagaaat taggtcgctt tcaaaaacat taggattaaa tacttttaat aaaccatcat
     6601 ttgcatgtct tgcgagtagg ataccttatg gagttgaaat aacagatgaa aatttaagaa
     6661 tagtagaaaa gagtgaagaa tatctatcca atttaggttt ttctcaattt agagtgagaa
     6721 tgcatggaga tatagctaga atagaagttg gacaggaaga gctaggtaaa ttttttgaaa
     6781 ataacaattt taataaagtt gatactaaat taaaaatatt tggctttaaa tatgttacac
     6841 tagatatgtc aggatataaa atgggaagca tgaatttaaa tgtgtagatt attttaaaaa
     6901 taaataagtt ttatagttaa tataaggaaa caggaggttt tatgaaaaat tatacgttaa
     6961 tatcgccatg tttttttgga atggaaaaaa tgctggctag agagattact aatttaggat
     7021 atgaaataat aaaaacagaa gatggaagaa taacatataa aactgatgag tttggaatag
     7081 caaagtcaaa catgtggttg agatgtgctg aaagagtaca tcttaaaatt gctgaatttg
     7141 aggcaaaaag ctttgatgaa ttatttgaaa atacaaaaag aataaactgg tctagatata
     7201 taccttatgg agctcaattt cctatatcaa aagcttcctc tataaaatca aaattataca
     7261 gtacaccaga tgtacaagcc atagtaaaaa aggctatagt agaaagctta aagaaaagtt
     7321 atttggagga tggtttgctt aaagaagata aggagaaata ccctattttt gtatttatac
     7381 acaaagataa agtaaccatt tctatagata caacaggaga tgctttgcat aagagaggat
     7441 atagagaaaa ggcaaataaa gctccaataa gagagacttt agctgctggg cttatttatt
     7501 taactccctg gaaagcaggt agagttttag tagaccctat gtgtggttct ggtactatat
     7561 tgattgaagc tgctatgatt ggtataaata tggcacctgg cttaaataga gagtttatat
     7621 cagaaaagtg gagaactctt gataagaaaa tatggtggga tgtaagaaaa gatgctttta
     7681 ataagataga taatgaatct aaatttaaga tttatggata tgatatagat gaagaatcta
     7741 tagatatagc tagagaaaat gctgaaatag caggtgtaga tgaatatata gagtttaatg
     7801 taggagatgc aactcaattt aaaagtgaag atgagtttgg atttataatc actaatcctc
     7861 cttacggaga aagattagaa gataaagaca gtgttaaaca gttgtataag gagcttggtt
     7921 atgcatttag aaaattaaaa aattggtcgt attatttgat aacttcttat gaagactttg
     7981 aatatgagtt tgggcaaaaa gcagataaaa aaagaaaatt gtataatggt atgttaaaaa
     8041 ctaacttttt ccaatatccg ggtcctaagc ctcctagaaa taataaataa gttttacatg
     8101 atttatttgt aaaatataaa attttattaa aataagtaaa acattatgat gccctgaaac
     8161 gtctaattat tgtgaggaga tttttgtgaa caaatttaaa gatttatagg attaggagga
     8221 gttaaatgaa agtgttaaag cttattactg tagtagccct gatgatgtta tttgttactg
     8281 gatgtaatat aaaaactgaa tctccagaac aattagcgaa gatacctgac tatgatgata
     8341 caaaaaaagt attgtatgat ggtattgacc agttactaaa accagattca tctatgatat
     8401 tgccttctaa tacaaaagaa gtaggaaaaa taaataaggt agatttaaac agcgatggaa
     8461 ttgatgaatt agtagtattt gaacaaaaag aagatttaag taataatgtg agtcaggtag
     8521 ggtttgtaac cttgagttac aatggagaaa aatacgtact tggagaccat tttttagaaa
     8581 atggcgaatc aatagaatat gctaattttt atgatttgga ctcagatgga tataaggaag
     8641 ttatcttatt ggttaaatcc aaagacaaaa cgaatatgca tatatataaa gtagtagata
     8701 atgaaataac aaaaatatat gacttggatg catcatggct tcaaaataaa gaagatttta
     8761 atgacatgaa agtaaaaatt ggatatatag atggagatga caagttagac atattgatgc
     8821 ttcatttgaa taataagact aatgaaatgt ttgcaagtgt tgcaaatttt gatgggaaaa
     8881 tgaaaatcaa agattctgtt aagtttgaaa atgtaaaaaa cttaagtgaa ttatatataa
     8941 cattaggtaa tgttgcttca tctgttggaa attcttctgc agctataaaa ggtattgtac
     9001 ttgatattcc tatattgaaa gataataact atattacgca gatactttat atgaaagatg
     9061 ggaaaattaa caaagctttt agtgattatg ataaaactat tactaaatct tattatatac
     9121 ctgtagatga tattgacaaa gataagatta tagaaatacc tatagttgca ggcagtacag
     9181 gtaataataa aaatacttat agttctaaat catctgcaac tataagttgg tatagatgga
     9241 atggaaaaga aggtgctgac tcaagtttaa tatttacaag tcagatatat tataattata
     9301 aatataattt taaattattt attccaaata atttatttga taaaatactt gttgaacagg
     9361 aatttgttgg agaaaaagca gtatttaaat tttactattt tgactattca gaccgtaaga
     9421 atttatttaa tatagtagta gagagtaaaa ataaacttga agatagaaaa aatacaggta
     9481 ctcaaaattc tattgtactt caagagagcg atgaatatac tttcttacta gttgtaaaca
     9541 atgcaaatga aatggataag ctagatatga ctatagacgc attaaaagaa tatttctcat
     9601 taatatatgg ttaatattat actcaattgg aggttttatt ttatgaagga aaagatactt
     9661 atactagaag atgaaattgg tattagaagt tttgttagta taaacttaaa aagggaaggc
     9721 tatgaaatag ttgaggcagg tactggaaga gaagctatag aaaaaatgac aacagaaaag
     9781 gatattacaa tagctctttt agatgtaatg cttccagata taagtggtat agaagtatgt
     9841 aaatttataa gggagaattt tgaccaagta ggtataataa tgcttactgc taaagctcaa
     9901 gaagatgata aaatagaagg atttatctca ggagcagatg attacatcat aaaaccattt
     9961 agtataaaag agcttttagt cagagtttct gctcttctta gaagagtagc aaaggatgat
    10021 tcaagtgtta agtcgagtga gatagtttct ccaccattta tacttgatat agacaaaaga
    10081 aaattattta aaaatggaaa ggaaattgag cttacaccaa ctgaattttc aatagtgaaa
    10141 tatctaatat caaatgctaa gcagtcgtta agtagagacc agatattaga cgaagtatgg
    10201 ggaactaact atttatatga ttttaaaata gtagatgtaa atataagaag gataagaaat
    10261 aaaatagaag atgacccatc aaaaccaaaa tatatacaaa ctatttgggg ttatggatac
    10321 tgttttagaa aggaagaata atagtgttac attttgaagg tctgagaaaa aaagtaataa
    10381 aaaactattt tataataatt attataatgg ttactctgtt tgaaggattg ttcatgtttt
    10441 acatacaaaa ctactattat gattctgtca aacagctact tgaatctgaa ataaaatatg
    10501 ctgatgaata taatgctatt acaatggaaa ctacaagttt tgagaaaaaa gtaaaaaata
    10561 tatttgataa acaaccctta actaaaaatt cagaatttgg aatttcaata atagataaag
    10621 ataaaaatat tatattagac caatatggtt ttaaaagtaa agaaaaagca aactatgaag
    10681 atgttaacaa tgcattaaaa gatataaaaa ctaaaaattt aacaccttat acttatagaa
    10741 taccagatac aggggagcat gttatgagta tctccttacc acttaaggta aataatataa
    10801 tagaaggtgt tgttagatat acagtatcat tagatgctat tgataatgca atattaaagc
    10861 aagctacatg gcttatatta gcaggaatat ttatacttat tatagctata ctaataagtc
    10921 ttaaatttgc tgagactctt ataaaaccat tacgagagct aaagaaattt gcaaatgaat
    10981 tggctgtagg aaattataat ataaaattag aaaagatgaa gattgtagat gatgaaattg
    11041 gtgatttagc acagacattt gaacacatgg cacatgagat tgacaaaagt gaaaaattaa
    11101 aagaggaatt tatatcatct gtatctcatg aactaaggac tcctcttaca tctataaagg
    11161 ggtggagtga aaccttaggt tatgaaagta taacaagaga agaactagac ttaggtttag
    11221 gcattataca agatgaaaca gaaagactta taaaactagt tgaagaatta ttagactttt
    11281 caaggctttc ttcagacagg ataaaacttc atgttgatat agttgatgtt gaaggtttaa
    11341 ttgtaggtgt tgtaaatcaa cttaaagtta aagcagctga aaaagatata tcacttttat
    11401 ttgaatttga aaatgaattt atagagaaca ttcaaggaga taaaaataga ttaagacagg
    11461 ttctcataaa tttaatacaa aattcattta aatttacgag tcaaggtggt tacataaaag
    11521 ttgtagcttc tcaagatgaa gagataacaa ccatatcagt agaggataat ggttcaggta
    11581 tagaaaagca aaatttaaat aaagtgttag ataaattttt ccaagaagat tataataagg
    11641 ctggtagtgg attaggacta gcaattagta atgaaattgt aaaacttcat ggtggaagaa
    11701 tgaaaataga aagtgaaaag aatgttggaa caaaaataac ttttaatata aaaaataaat
    11761 ttgctaaaca agcataaatt cttagaaaga ggattaagat gagaaacata aaaatgatag
    11821 tagcatacga tggttcaaga tataaaggat atcaaaaatt aggtgacaat aatatgacta
    11881 ttcaagaaaa acttgaaaat gttttaagta aaatgactaa tgaaacagtg gagataatag
    11941 gttctggaag aactgatatg ggagctcatg caagaggaca agtggtaaat tttagaacta
    12001 attgtatgga ttctttggat aaaattcaaa aatatttata tgaatattta ccagaagata
    12061 tagttgtaaa aactgttgaa gaagttgatg aaagatttca ttcaagatac aatgtaaaat
    12121 caaagactta tatgtataaa attgacaata ataagtatca taatcctttt ataagaaaat
    12181 atgctactca tgtaagtaaa aaattagatt tagatagaat gagaaaagca agtgagtatt
    12241 tagtaggaga acatgatttt actagttttg cttcttctaa atctaagaaa aaatcaaatg
    12301 taagagaaat ttattctata aatataaaag aagatgataa tgttatagaa atatatgtag
    12361 aaggaaatgg atttttgtat aacatggtaa ggataatagt aggtgctttg atagatgttg
    12421 gtctaaaaag aagagctcca caagatatta agtatatgct tgaatcaaaa gatagatgtc
    12481 aatcatcaga tactgcacca gctaaaggac tatgtctttg gaaagtaaca tattaatcaa
    12541 ttatataaaa ctctctttaa aataaaaata aaataaatta tatagttgac ataaatggaa
    12601 aaataaacta ttatatattt tataagagag atataaaact ttatatttaa atcctgtgag
    12661 aaagagagta acttctatgt gttttataga gagctgagga tggtggaagc ttggcaaata
    12721 agtattagtg aaaagaactt tggaggatac taattgaatt tagtatgtta gtaggtaatc
    12781 tcgccttaag agaaagagtg gataagttta tcttatcaat tagagtggta acgcggatat
    12841 atttcgtctc ttggtttttc caagaggcgt tttttaatat atttaattat tagtgtttat
    12901 ctggtatgtt gaacatttac taattgatta gctaagttta tcaataagag tggtaccgcg
    12961 gatatttcgc ctcttagtat tttaaaatac taaggggttt ttttagtatt aaaatgattt
    13021 tatgtgagtc taaattctca gagtcattca atattaagaa tttctataaa ataaaaatta
    13081 taatttaaga ttgggaggaa ttaaaaatga aggaaaaagt agtattagca tattcaggag
    13141 gacttgacac atcaatcata ataccttggt taaaggaaaa ttatgaagat atagatgtta
    13201 tagctgtttg tggaaatgta ggtcaggaag ataaaatgga agatgtatat gaaaaagctt
    13261 tacaaagtgg agcatcaaag gcatatgtgg atgatataag tgaagaattt gtaactgaaa
    13321 ctatatttaa agctgtaaaa gcagaggcta aatatgaagg aaaatactta ttaggaactt
    13381 ctttagcaag acctataata gctaaaaaat tagttgaagt tgctcataaa gaaggtgcaa
    13441 aatatatatg ccatggatgt acaggaaaag gtaatgacca agttagattt gaagctacaa
    13501 ttgcagctct tgacccaact ataaaagtta ttgcaccttg gagaatttgg gatataaaat
    13561 caagagaaga tgctatagac tatgctgaaa aacataatat aaaggtaaca gcaactaaag
    13621 ctaaaatata ttcagtagat gccaaccttt ggcatgtttc aacagaaggt ggagatatag
    13681 agcacctaga aaatgaacat aaaaaagatg tttataaaca atgtgtagac ccagaagatg
    13741 catgtgatgt agctgaatat gtagaagttt actttgaaaa aggtgtacct aaaaaggtaa
    13801 atggcgaaga attatctcca gttgcactga ttcataagtt aaatgagttg ggttgtaaac
    13861 atggaattgg tgttatagat atagttgaga atagacttgt tggtatgaaa tcaagaggta
    13921 tatatgagac tccaggagga acaatccttt atgaagcaca taatatttta gaaagtgcta
    13981 ctttagacaa agatacatta catttcaaac aaatggtatc ttataaatac ggagaactta
    14041 tttacaatgg actatggtat tgtaaattaa gagaatctat agatgcattt atggaacaaa
    14101 ctcaagataa tgttacagga acagtaaaag ttaaacttta caaaggaaat ataaaacctg
    14161 ctggaatatt tactgaaaat gctctttatg atgaaggaat atcttctttt ggaaatagtg
    14221 aactttatga ccacaaagat gcagaaggat ttattaattt attcacttta ccattaaaaa
    14281 tcagagctat gaaagctgga aaataataaa ataaattatt taagagtgta taaaaacgat
    14341 ttttaggttt ttatatgctc tttttttatt tgaatttatt aaattataca gtaaatagta
    14401 taaaaaaata tattatagtt ccaaatggct taataatgtg aaaatataag acctaaaata
    14461 taaattttat aaatacaata gttattgact ctctcattgt aagagggttt atactgaatc
    14521 taatgaaaat ttatagtgag gagatagatt atatgagaaa aataattgaa attaaacatc
    14581 attcacatga ttatgagtgt atgtggaatg gtatagaaga tttatatata aataaaaccg
    14641 gtgaatacct tccaaacgat tttttctttt tactgtcagg ttttggttca ttttgttata
    14701 tgaaaacaaa taaagctgat ttgaaaagaa tggtagcttt gggagatgga aggacaaaac
    14761 agatgtataa atttttagca ccaattgttg gatttgaata caaacatcat gagtttaaaa
    14821 agtatgagca agcattaaag aaagcaaaat ctgaaattga tgatggatat ccagttattt
    14881 taggagcttt agatatgtat tatctaccat attataagaa gctatatcat aaagaacata
    14941 ttccttttca ttatatatta atggtaggat atgatgatga aggaatatat ctgtatgatt
    15001 gtggtagaac agaattatta catctttctt atgataaatt acgtgaaagc atgaattgca
    15061 attcccctgg attaagcaaa gaaaatacta tttgcacaat aagaatgaat acttcaaaga
    15121 ataaatataa cattgctaga gaagctattg ctataaagcg tgatatgttt ttaaatccac
    15181 ctaaaggatt tttgggatat aaaggttttg aaaagtttat taaagagttg ccacagtgga
    15241 acactgaatt ggataaggat gattatgata agattttgac caatatggtt atgttttttg
    15301 gaacagtacc aacaattcca aatgcaatca aaggaattaa agaaccagat actgttcaat
    15361 ttaaaggtgg atttgataaa atgagtagaa tgctcaacag tattggggag gaatacaaaa
    15421 acaactcttt tatacaagta gctgatattt ttgataaaac tgctattata attgagaaaa
    15481 tatccaatat tataatagat tacttaactc aaacatgtga tgatacagaa caacttccgt
    15541 tattgttctc tgaggtctta gagcatatga aaacaggata tttaatcttg gatgtataaa
    15601 aaatatattg ttgaccctaa cattacgtaa tagtgtaata tgaaaatata gcttaaatat
    15661 attagtaggt attgatggct gtaaaattaa aatttgaggt gtggatatga gaacagtgaa
    15721 acaagtttct gatttaactg gaataagtgt gagggcatta cattattatg atgaaatagg
    15781 tcttttaaaa ccaaataaaa ttacagatgc aggatataga ctttatgatg atgaatctat
    15841 taaaactctt caacaaattt tattttttaa ggagattgat attcctttaa gagaggttaa
    15901 ggaaataatg tcaagccaat attttgataa ggttgaagct ctaaaaaatc aaaaaaaatt
    15961 acttatttta aaacgaaaga gactggatga attgatagag cttataaatc aaactctaag
    16021 aggagaagga aatattgatt ttaaagagtt tgatatgagc gagtatttta atgttttaga
    16081 agaatttaaa agagagcata ggaataaggt aattaaaatt tatggtagtg tagaaaaata
    16141 caatgaatat atagaaagag ttaagtctaa tgaagagaaa attgctaaaa tggctataaa
    16201 acaatatgga actattgaga agtttgctaa agctataaaa acaaatttta gcagtgatat
    16261 attgaattta ggagaaaaat ttgatagata taaaaatgat tgtttaaaag aaaaacatcc
    16321 aaaattaaaa gaattatata gaaagcttgt agaagattta agtaggaatc cttcttcaac
    16381 agaccttcaa gaaatagcaa aagcgataac agatatatct aaaaaagatt atgaaatttt
    16441 ctctatggat actggtgatg acaactggta ttatatggtt caaaattatc tagtaaatcc
    16501 tatgtggata gaagaagtag ataaaaagta tggaagtgga gcaggaaagt ttattggaca
    16561 agtactaaag acttatctaa gagatagaaa accaaagata aatacattgt atgaaaaact
    16621 tgtagaagat ttgagtagag attgttcttc aagggaagtt caaagcattg ttgaagaaat
    16681 agacaatgaa atgaaaagaa gtaatgaatt ttataaaata gacaatggtg aaagatactt
    16741 tgattatatg tcagagcttt atttacaaga ttctaactat ataaaagtaa ctgataagaa
    16801 ttatggtgat ggtgcatcta agtttattgg agaagctttt aagatttatt ttgataataa
    16861 taattgttga aaatttggaa gtaaaaaata tgtaagtttt ataaaagcac aaaaataagg
    16921 atgtagatta gctccatcta tatccttatt taaagttatt aaaatatata gtttacatca
    16981 aacttaacac tttcaataat atttcccaaa tatgttttta tactttcaac ttcttctaaa
    17041 gattttaatt tattttcagt ataaattgct ttgtccagaa tattaaacct taatcctatt
    17101 tcatcaaagt actcatgatt taaaactttg taccaatggt ttttttcttt attccaactc
    17161 gtagatattg aatcagcttc tttttgagct ttttcccaat cttcattttc tatagatttt
    17221 tctaaaacag atatattgtc tttatatcct tctgtaaaat catatagttt attgttaacg
    17281 taaaatccaa ataatacaaa taagatagtc catagtataa caaatgttgt agatttcaat
    17341 attaatcacc ctttttattt tgaataaata ttttgtcatt ttcatctaaa acacaaataa
    17401 gaacatcttt aaaagtttct atgtgattag attttaaaat acccattaac cagttagtat
    17461 ctttttgagc tatgtctaga tttttattta ttattctacc atccagtata agtgggatag
    17521 gtaaatgatt aaaagctctt ggaggagtac tattgtagct tgatgctggt acaacactta
    17581 gattaccatc agtctccaaa atagcatatt gtacatcttt taggttaaag tatccttgaa
    17641 tcctaagttg ttctaataat tcatctatac taattctttc ttttttaagc tctttatata
    17701 caatttttcc tttatctatt aatacagaag gtttacctga taaaaatgaa cttaattttc
    17761 tgctttttaa tgataagaat gaaattagag tctgcatgat tacaagtcca gatattgctg
    17821 caacaccatt tatgattggt atattattat tttccattgg gacagatgca acttctgcaa
    17881 ttaatagtgt tataactaaa tcaaaacagt tcatttcagc tatttcacct tttcccatga
    17941 ctctaagtgc aattagcact gttatgtata atataatact tcttattaat actactgtca
    18001 tatctatcaa ttactccttt aaaaaatatt tacacttagt tagtatatcc tatataaaaa
    18061 atttaattca aagtataaaa aaccttaaat aattggattc aactatttaa ggtttttttg
    18121 ataattttaa tattaaattt tttatggatt ttctgttact tttatttatt ttaataacag
    18181 attcaacaaa actcttttta tctcctaatt ttaagataaa atcaggatat tcttcaaatt
    18241 cattgagttt tattaatttg aaagaagaag atagattttt aaagttaata attttagagt
    18301 tattcactaa tacacttctt tttttaaaat aaatttcttt tttacttata tttagtatag
    18361 ttaatatttg tttaagatat attattatat cttctggagt tctatcaaat ttgagttcaa
    18421 aattttcatc ttcaaagtag ggaatataat ataaaggtgt tttgagagca ggtaatttat
    18481 tatataattc ttcaagaata tcgatatttt taggggagtt aaagaaaaag catttacata
    18541 cattcattaa atccacagca tctgaaagtg agttatgttt aatatctcct tctacagaaa
    18601 aaattttttt catattcagt aaagatattt gcttagataa gattctatta ttgtatgtaa
    18661 tatgttgaga tataaaaggt tgaatgtcaa tcatcatatt aaataactct aagcatttac
    18721 ctgtatattt atacactcta aatgaagtta gaaggccagt tatatcaaaa tcaccccaat
    18781 tatatattgt aacatcatca aatttacaaa accatttata aaaatcatcc ataacatata
    18841 aaagattagg agcattattg atatctagtt ggttcaattt ggttaaattt ttacatttat
    18901 ttgaaagtat tttattgtat tttggcttaa ctaaagagta ataattatct attgtattaa
    18961 attcgttatc aactaaaact ccaccaatag aaattaattc cgcaccatta tattcttttg
    19021 gtttattttt attatcatct agtatattaa attcaaagtc tataaataac ttgtatttca
    19081 taaatctaaa gcacatcctc aggtaaatta tttattgagc ctaagcatca taagaatcaa
    19141 tagatataat gactctaaac atcaaaggtt cattacaact tttatttatt tcataattta
    19201 attcaaataa atcttttaag atataattta taagtattct ttcccaaccc atttttaaat
    19261 taactttaga gtctattaat atattttcta tctttttaaa tatttctata tttgctggta
    19321 ttatactgag ctcaatatta cttttaaacg ggttagactg taaatctgtt ataagtatat
    19381 tttttaattc ctctgtaagt tcagaaatta aactatcacc tatgtatttt tttatgattt
    19441 cctctctaat ttcttttaaa tttagcaata ttagtacctg ctacttacat agtagctttt
    19501 cctttccttt taatactatt attcattttt gaatcttatt tagatatatt ttaagattaa
    19561 aagtctttag ctatataatt ttttacccat ttttaactta tattaacata ttacaggctt
    19621 atatctccac cctgtttaca ttgaggatgg agtatattgc ctattttgat aaaaatgata
    19681 ggttgctatt tgcctattcc tttttctgat aatttttcta acatatcttt ggtcatttta
    19741 tctaaatcat aactaaactt aaagttccat tcttttactg cactactact gtctagagag
    19801 ttaggccaag aatcagctat actttgtctt acagggtcta catcatattc tatcacaaaa
    19861 tcaggaatat atttttttat agaatcagct atttcttcag gagaaaagct catagcagta
    19921 atattaaaag catttctatg gatgagttta tcagctggag cttcgattaa atccactatt
    19981 gattgaagtg catcaggcat atacatcata tccatttttg taccttctgc tatgtaagat
    20041 ttatatctct tattttttaa tgcctcataa tatatatcaa ctgcataatc tgtagttcct
    20101 ccaccaggag gcgtaacata agaaataaga cctggaaatc taacacctct agtgtctact
    20161 ccaaattttg agtgataata atcacatagt aattctccag aaactttagt cacaccatac
    20221 atagtattag gtctttgtaa tgtatcttga ggagtcatat tttttggaga attttcacca
    20281 aaagcagcaa ttgaactagg tgtaaaaaat ttacaatcca attctttggc tatttcaaga
    20341 ccatttatta atccattcat atttaagttc caagcttcta gaggtttact ttcagcaact
    20401 gcagaaagta aagatgctag atgaattata gtatctacat catatttttt tgcaatttca
    20461 aaaaaacgat tcttatctgt aacatctaat atctcaaata taccagattc acatactgga
    20521 ttaccttctt ttactctcct tgaactagcg attacatttt gttctccata ctcatttcta
    20581 agctttattg ttaattctga acctatttgt cctaatgcac ctgttataag tatttttttc
    20641 aattttacaa cctcctaagg gtttaattta tgtagtacta cttattttta ttttagcaaa
    20701 tcttttgttt aaatacaaag aattaaagat aataatatac gacttaattg aatgaagtgc
    20761 agtaagtgcg taaaaattta aagctaatat ataatggtct attgtataac aataaaagag
    20821 tagattaaat tattatatat agattgtgtg actaagtcac agaaaataga gctaatttaa
    20881 tatataataa aagcatgtca agtaaagctt taaattaaag taactttata taaaaagtaa
    20941 tataaattga taaaattata aatttattta tagtgaatat aggttggatt ttatagatac
    21001 aaaaatagta tatatgatat gtagaccatt agcatgttta aagtagcaaa acatataaaa
    21061 taaaatttga aaggaagtat aaaaatgaca agaccatcaa tatatcatag ccaaggatac
    21121 acttgtgcag aggcattaat aaagtcttat aatgaggaac acaacacaga tataccaatc
    21181 tcaataggaa gtggtatggg ggttggaatg aatgttggaa gtgtttgtgg agctgtaaat
    21241 gctgctgttg ttataatagg gtatttaaat gggcgaaata gtaatttaga tgaaaatata
    21301 gcaaggaagt attcaagaga gctattgaat agagtaagaa ataaatacag ctcagaaata
    21361 tgtgtatctc ttaaaaaaaa taaagtaact tgtgaagaaa taataaattt cacatatgat
    21421 gctctaaatg atatgctaaa aaatcaaaaa taattctaag aaacaagtat tttacattcg
    21481 atagaatact tgttttttta tgatattttt aataagtatt agtttattat aatttttaaa
    21541 tcaattttat tatattttaa ttgaaataat ctactttgaa aattactaac tgacaaaaga
    21601 atatgattat agtatagaaa aaatgtaaat tatttaatat taagtgagag tatatgctta
    21661 cctatataaa atcgtataaa ttaatggcta aatttataaa ttataaagaa atatatagga
    21721 a
//
LOCUS       DAMJVG010000065        21268 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.065, whole genome shotgun sequence.
ACCESSION   DAMJVG010000065 DAMJVG010000000
VERSION     DAMJVG010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21268)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21268)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21268
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.065"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            296..817
                     /locus_tag="PC512_002673"
     CDS             296..817
                     /locus_tag="PC512_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2442407.1"
                     /translation="MDIAKLILNPARLRILQYIRLYGSVRTSDIVKYLNDIPRATVYH
                     HVKILEENNMIEVIKENRVRGTIEKVYALKEYTTSMEGETFVALSTAFYVGLMQEMNE
                     YFSRKEQDHKKDNVFFSSALLYMSDNEYENLLKSIADLLKPYIEQKPKSNLKLRKLSI
                     ISSPPVADNDKTK"
     gene            851..1627
                     /locus_tag="PC512_002674"
     CDS             851..1627
                     /locus_tag="PC512_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2442408.1"
                     /translation="MKFHEFGNKNRPHIMLIHGGGNAWWNYLRQAEVLSNKYHVILPT
                     LDGHGEEYETTYISTEDTADKLISYIDENCSGHLFALCGVSLGGQIVMELLSRKPNIT
                     KKAIIDGSICYPRPLMARFCIAGIRFFGGLLFSEKACRFQIAMMPKLLPENMQYPDEI
                     KAYYMTDMPHVRKETFYNMYRTYMMNYTLKENVKKTTAQVMYWYGEKEMKCVKKSAKL
                     FQSYVPSCEIYEAKSYNHGYLSLYLPNEWLEIAEPFFQKE"
     gene            1969..2922
                     /locus_tag="PC512_002675"
     CDS             1969..2922
                     /locus_tag="PC512_002675"
                     /EC_number="3.4.24.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GPR endopeptidase"
                     /protein_id="HDF2442409.1"
                     /translation="MISVRTDLALEASEMCEKSQEGSSIPGVKIETKELENCIVTKVE
                     VIDRQGAEIMNKDIGKYITLESNLMKFDDDESREEMISYLKEELVDIFGQDKNKKTLV
                     IGLGNRNITSDALGPKSVSKTLVTRHLFKNYNKDYDDDFTEVSALSPGVMGVTGIETS
                     EIVKSLVEKVKPDRVVAIDALASRKMERVNSTIQISTAGISPGGGVGNTRKSLTKETL
                     GVDVIAIGVPTVVDAATLTIDVLDMAIDNLIAQSEETESFYEMLKKLKEEEKYHLIKD
                     SLDPYDKNLIVTPKDIDDTIENLSIIISEGLNRSLHPGRLV"
     gene            2940..3959
                     /locus_tag="PC512_002676"
     CDS             2940..3959
                     /locus_tag="PC512_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein P"
                     /protein_id="HDF2442410.1"
                     /translation="MFKKCIKVVTLTFILVCILPGKSLALNQDDFLKFLVNSSYPEAK
                     VEGNDTENKKNNKNKETSKENKEESKEGNTKSKDASKVDNKKESEKEYIKLYVGKENV
                     PDIESKNSDTTETNTTSSSDYKDDLRVTKENPRILIYHTHGCETYSNSPDGNYHSRDK
                     KNSVMEVGSALTSALDSKGWGVVHTTKYHDYPSYNNSYASSLKTIQSILPKYNSVDIA
                     IDLHRDARDLTNPATKEKDHLKYTTMINGERVSKFFFVVGGKNTNRKQLRALAEDITA
                     FAEKKYPGLVSPIVEKDYARFNQFAVKNHMLVEIGNNATSVEESKATTKYLAEILDEY
                     FKQKN"
     gene            3990..4241
                     /locus_tag="PC512_002677"
     CDS             3990..4241
                     /locus_tag="PC512_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442411.1"
                     /translation="MSRLEKNIESKSKLRKYKYIMRILFLITMIICTSVCVFIVDSNA
                     KSMLGMKQYDFPSIKFDITKFDFDIPNFDIHEIIKKFNK"
     gene            4523..6328
                     /gene="lepA"
                     /locus_tag="PC512_002678"
     CDS             4523..6328
                     /gene="lepA"
                     /locus_tag="PC512_002678"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HDF2442412.1"
                     /translation="MDNKQSRTRNFSIIAHIDHGKSTLADRLIQQTGLVSERDMKSQL
                     LDNMDLERERGITIKLQNIRLMYKAKDGNEYYLNLIDTPGHVDFNYEVSRSLAACEGA
                     LLVVDAAQGVEAQTLANVYLAIDQDLEILPIINKIDLPSARPEEVKNEIEDLIGLDSS
                     EAPLISAKTGLNIEDVLEDIVKNVPPPKGDNEAPLKALIFDSYYDAYKGVVAYVRVFE
                     GTVKKGMTIKMMNTNKKFEVTEVGVMAPGQTELSELSAGDVGYIAASIKDIRSCRVGD
                     TITDSNNPTEEPLPGYKKATPMVYCGIYPGEGEKYENVRDALEKLQVNDAALEYEAET
                     SAALGFGFRCGFLGLLHMEIMQERLEREFNLDIITTAPSVIYRVTKMDGEVVMIQNPA
                     NLPEPSEIKMIEEPIVKGDIIVPKDYVGVVMELCQERRGNMLNMEYIDDRRVMLHYDL
                     PLNEVVYDFFDALKSRTRGYGSLDYEVKGYVASTLVKLDILINKEQVDALSFIVHETR
                     AFPRGKAMCEKLKGEIPRHQFAIPIQAAVGNKVIARETISALRKDVLAKCYGGDISRK
                     KKLLEKQKEGKKRMRQIGSVEVPQKAFMSVLKLDE"
     gene            6477..7814
                     /locus_tag="PC512_002679"
     CDS             6477..7814
                     /locus_tag="PC512_002679"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HDF2442413.1"
                     /translation="MINIEIPKKVDYIIKELEKNGYEAYIVGGCVRDCLLERVPNDWD
                     ITTSARPEVVVELFEKTIPTGIQHGTVTVMIEHEPFEVTTYRIDGNYSDGRHPDSIEF
                     TNNIVKDLSRRDFTINSIAYNSKTGLVDPFNGYEDIQNKYIRCVGNPVDRFEEDALRM
                     LRAVRFSAQLNFKIAEGTKQSIHKKADLIKNVSIERIQTEFNKILVSDSSKLNLLKST
                     GLLKFIIPEICELEDVTQHNPYHIYDVQKHTLIATEVIEDELYLKLTMLFHDLGKKVT
                     KTTDKNGVDHFYTHSRESVKIAKKILKRLKYDNYTINKVLILIQYHDYRIEPKRKIIK
                     KLLNKLEDVELFEDLIKVNWADTLAKNPKYAKQKILNLIECEKEFKHIINQKECFNLK
                     DLAINGKDLISIGIKPGKDIGYILNKMLEIVINNPELNEKEILKEKALNIYTF"
     gene            8047..9360
                     /locus_tag="PC512_002680"
     CDS             8047..9360
                     /locus_tag="PC512_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDF2442414.1"
                     /translation="MHTQLQKTIGLSAALSTVVGMVIGSGVFFKPQAIYTTTNGAPGL
                     GIIAWLLGGFITITAGLTATEISAAIPKTGGMMIYIEEIYGEKLGFLTGWMQTVLFFP
                     GTSAALGVIFAQQASELLGMSPNNMANVLPIAIGVILFLALLNIIGSSLGGKVQTVAT
                     IGKMIPLILIIVFGFIKGQSSEVLNPFVGDGVNASNALGQVLIATLFAYDGWINVGAI
                     SGEMKSPEKDLPRAIVGGLSLVMAVYIIINIAYLWVVPASELATVTSPATLVATRLFG
                     NIGGKVITVGILISVFGTLNGYLLTGSRIPYTLAEMGTLPASKTLLKVNSGGSPVNSI
                     LLITVLACVYALSGQFNLLTDLTIFSIWVFYVLTFIGVMRLRRQKPDLHRPYKVPLYP
                     IIPIIAILGGLFVIINQILTSTVISLGGIFITLLGLPVYYYMKKR"
     gene            9532..10707
                     /locus_tag="PC512_002681"
     CDS             9532..10707
                     /locus_tag="PC512_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HDF2442415.1"
                     /translation="MLGLYVHIPFCVKKCKYCDFNSYKMDIDSKKRYIEDLKIEMELY
                     SNKLYKDNKYKNKECCSLNKNDKITSIFVGGGTPSILTSDEIREVFISIKEMFDIDEN
                     AEITIECNPGTLTLEKLKTMKEIGINRLSIGLQAIQEKHLNFIGRIHTYEEFEKNYKD
                     ALSVGFKNINIDLMYSLPNQTLCDWKETLEKVVHLNPTHISAYSLILEEGTELYNMYE
                     SNKFELIDENVDIEMYEYTINYLKSKGYNQYEISNYSKEGYNCEHNILYWECEHYIGI
                     GAGASGYINENRYNNVESLEDYHLSLVKREKPIQENEILSEKDMIEEKIFMGLRMNKG
                     IKFEDFKKKFGIDFREKYNKQIEMLLARKLINQSFEGIQLTQKGREISNSVFIEFME"
     gene            10810..11829
                     /gene="hrcA"
                     /locus_tag="PC512_002682"
     CDS             10810..11829
                     /gene="hrcA"
                     /locus_tag="PC512_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcription repressor HrcA"
                     /protein_id="HDF2442416.1"
                     /translation="MELNERKLNILKAIVKDYIETAEAIGSRTISKRHDLGVSAATIR
                     NEMADLEELGYLIQPHTSAGRVPSEKGYKLYVNSLMSKSELDDNDKILIEQCMNHNIN
                     HIKELIHETSKLLSQLTNYTTVAVTKSLINQSVIKHIQLVAMNDNNILLIVVTDKGDL
                     KKANLTTNVYLDQSKLNLISDNLTRKLLGKSITDLDDNLIAFIKYEISEYSGLIDELL
                     NALNSNMKEEDFSLSLNGATNIFSYPEFNDVLKAKSFLNMLEKKETIADIIKSKGIQK
                     DNLNIIIGSDNDCELAQDCSIVTATYNVDRDLVGRISFIGPTRMDYARIYSIINYMSL
                     LINRK"
     gene            11859..12479
                     /gene="grpE"
                     /locus_tag="PC512_002683"
     CDS             11859..12479
                     /gene="grpE"
                     /locus_tag="PC512_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HDF2442417.1"
                     /translation="MDKKNEQQEVREENDTSINQESETQVELEEEVVNEECETSSEKT
                     DEKEVDDENVTDINSKLAEKKLQDELDELNDKYQRLQAEYANYRRRTQQEKETIGVFA
                     NEKIITELIPVIDSMERALDACEDKEDTMYKGISLVHKQLIDTLVKFGVEEIEAESKE
                     FDPNLHLAVMQESVDGVEANQIVMVLQKGYKLGTKVVRPSMVKVSC"
     gene            12571..14418
                     /gene="dnaK"
                     /locus_tag="PC512_002684"
     CDS             12571..14418
                     /gene="dnaK"
                     /locus_tag="PC512_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000034699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HDF2442418.1"
                     /translation="MGKIIGIDLGTTNSCVAVLEGGEAQIIANSEGMRTTPSVVAFTK
                     DGERIVGEPAKRQAVTNADKTITSIKTHMGTDYKVNIDGKSYTPQEISAIILQKLKSD
                     AESYLGQTVTEAVITVPAYFTDAQRQATKDAGRIAGLDVKRIINEPTAAALAYGMDKL
                     DQEKKILVFDLGGGTFDVSILEIGDGTFEVLATAGNNRLGGDDFDQIVIDYLAEEFKK
                     AEGVDLRNDKMALQRLKEAAEKAKKELSSTMSSNINLPFITATAEGPKHLNIDLSRAK
                     FEELTRGLVEKTMEPTKTALQDAGLSTGDIDDVLLVGGSTRIPAVQEAVKKFIGKEPH
                     KGINPDECVAAGASIQAGVLAGDVKDLLLLDVTPLSLGIETMGNVMTKIIERNTTIPT
                     KKSQIFSTAADNQTAVDIHVLQGERSMAYDNTTLGRFQLTDIPPAQRGIPQIEVTFDI
                     DANGIVNVSAKDLGTGKEQKITITSNTNLSESEIEQKIKEAEMNAEADKQKKEKIEAF
                     NQAESTIYQTEKTLNELGDKISSGEKEDIEKAIADLKAVKDNQDATAEELKKATDEVM
                     TKFQKVSQEMYQKAAQEQQAAQGAEQAQDNGPKDDNVVDADFKEVDEDK"
     gene            14629..15783
                     /gene="dnaJ"
                     /locus_tag="PC512_002685"
     CDS             14629..15783
                     /gene="dnaJ"
                     /locus_tag="PC512_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HDF2442419.1"
                     /translation="MSTKRDYYEVLGISKGAEAQEIKKAYRKLAMKYHPDRNPGDKEA
                     EEKFKEINEAYEVLSDDTKRKTYDQFGHDGLNGQGGFGGQGGFGGQGFGGFEDMFGDI
                     FGDMFGGSFGGGRARRRGPQRGADIRQSVTISFEEAAFGKKMSIKVNRSEECEECNGT
                     GAKPGTSKKTCSTCNGTGQVRTVQRTPFGNIASSRPCSACNGTGEVIESPCSKCHGTG
                     NTRKVKTIEVDIPAGIDDGQMIKLSGQGEVGEKGAPRGDLYIVVNVKSHPLFTRDGND
                     IYFEMPITFVQATLGDEIEVPTLDGKVKYSVPEGTQTGTVFRLKEKGIPRIRGNSRGD
                     QYVKVVVEIPKKLNDKQKELLREFAKECGSNVHEKKKTFGQKIEDMFKKK"
     gene            16749..17684
                     /locus_tag="PC512_002686"
     CDS             16749..17684
                     /locus_tag="PC512_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDF2442420.1"
                     /translation="MYYIGVDIGGTGIQAGVVDNYGKIIFRSECKTVIEKGFEGILND
                     IKIMIYKLLEDNKLTMSDIKSIGFGVPGFINKEGLVTCVNLKWNKKAFNKELKKRFPD
                     VEIHGENDATVAALGEAKFGSMKGANVGVLYTLGTGVGGGIVINQKVFSGAHGLGSEI
                     GHQIIGENYFNCNCGNNGCVETFCSATAIIKYSQKLIEEGEKSRILDLAEGNLENVNA
                     KMVFDAYRENDLVAIKVINRFKEYLAKTFANTINSLDPEIISIGGGISKSSDIILDGI
                     EGLVRKFVLYKTEDIATITCATLGSDAGIIGAAFL"
     gene            17720..19093
                     /locus_tag="PC512_002687"
     CDS             17720..19093
                     /locus_tag="PC512_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2442421.1"
                     /translation="MGKTNARRTLFLIAIGSGTMLNPLNSSMISLALHSIQNDFHISF
                     TTVSWIVSAFYLASAIAQPVSGKIGDLIGRKVLFLSGLMLVILSASIVPLVQSFFILI
                     FIRVIQAIGTSTLYPSGVALIQNNIKERQSSALAVLTIFASTTAGLGPTLGGLLLDLG
                     GWHAIFLVNIPVVLVSICLGYFLFPKEVKEKKSIKETLKNVLSRLDIIGILLFSIAMI
                     FILLFLLSMKESFNLEQLVFGIILMCLFIWHELRTKLPFIDIKLFVSNPKLSKVYLQF
                     IILNFFNYILFFGLPSYFQDALHYSAKSTGLFMLFMSGIGIFISPLTGKWIDKSGTRF
                     PLVTSSIFMFISAVLLSVVFIHIPVIGKGIILSLAGISYGVGNVALQSSMFEESPRDS
                     IGTASGLFQTSRYLGSILATVLLGMVFEVNITSEQFQILGYVMVVLGTISFLLNFILK
                     KELRKVE"
     gene            complement(19281..20048)
                     /locus_tag="PC512_002688"
     CDS             complement(19281..20048)
                     /locus_tag="PC512_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2442422.1"
                     /translation="MEELKDFLERQLNKKINIYPYENQKLDASSHLVTFNNAIYVIDF
                     LDKNNLDNLKGNFYLIYQSHIDFEYLKNIFYNLFEDINIIQHNGFFIVNSKYNLDINV
                     TTQNIIETETYQSTYIFYLGELDSKADFDFRLQLCSDLLPHIIKDNAENKFLNLFDLI
                     RYKTLDLINEDNILNKLIDFNKIKSIDEELLYTGIKFINNDLNISKTSTSMFLHRNTL
                     VYRLEKINEILGFDLKNFENAMIFYLSVKSYFLYKKI"
     gene            complement(20078..21187)
                     /gene="ugpC"
                     /locus_tag="PC512_002689"
     CDS             complement(20078..21187)
                     /gene="ugpC"
                     /locus_tag="PC512_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003242648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HDF2442423.1"
                     /translation="MSEVILKNISKLYSNGFNAVKNINIDIKDKEFIVLVGPSGCGKS
                     TTLRMIAGLEEISEGELYIGDKLVNDIEPKDRDIAMVFQNYALYPHLSVYENMAFALK
                     LRKLPKDEIDKKVKEAAKILDLLPLLNKKPKTLSGGQRQRVALGRAIVRNPKVFLMDE
                     PLSNLDAKLRTAMRTEITKLHQQLGTTFIYVTHDQVEAMTMADRIVVMKDGVVQQIAT
                     PQDVYDYPANIFVAGFIGAPQMNFIDVILIEENDEIYAQNEHIKLKLNKEKHYDLIKD
                     NYINNEVVIGIRPEDIHVEDTFIKSNPDTCFKSRIEIKELMGAETYAHLKLGENTITI
                     RFDSKNRINVGDDLTLSVDNSRVHIFDKETTLAIR"
BASE COUNT         8312 a         2394 c         3747 g         6815 t
ORIGIN      
        1 aagaaattac tcatttttgt aaatttaatg aaaaattata aaaatataaa tttatatgct
       61 taattaagat aatttttcca ataatcaaga taattttttt cattagtatg tatgatagat
      121 gcatcaaaca atataactaa tatgttagaa ggttatatgt aattaatgtc agtgtttata
      181 tagaatagca tttgtagcat ttattatagt tgtaattact atttatatca tagacttgaa
      241 tagtctaaaa aaatagacta taatattttt atagactaaa gaaagggctg ataagatgga
      301 catagcaaaa ctaattttaa atcctgcaag gcttcgtatt ttacaatata ttcgacttta
      361 tggcagtgtt cgtacatctg atattgtaaa gtatttaaat gatattcctc gtgcaacagt
      421 ttatcaccat gtaaaaattt tagaagagaa caatatgatt gaagtaatta aagaaaatcg
      481 tgtgcgtggt actattgaaa aggtttatgc actaaaggaa tatacaacat ctatggaagg
      541 agagaccttc gttgcacttt ctacagcatt ttatgtaggt ctgatgcagg aaatgaatga
      601 atactttagc agaaaagagc aagaccataa aaaggataat gtatttttct cttcagcatt
      661 actatatatg agtgataatg aatatgaaaa tcttcttaaa agtatagctg atttattgaa
      721 accatatata gaacaaaaac ctaaatcaaa tctaaaactt agaaaacttt caattatatc
      781 ttctccacct gtagctgata atgataaaac aaaataacat gcaacccatt tttataaaag
      841 gaggttatat atgaaatttc atgagtttgg aaataaaaac agaccacata ttatgttgat
      901 tcatggggga gggaatgcat ggtggaacta tttgcgacaa gcagaagttt tgtctaacaa
      961 atatcatgtg atacttccta cattggatgg tcatggagaa gaatatgaaa caacatacat
     1021 ttctacagag gatacagcag ataagttgat atcatatata gatgaaaatt gcagtggaca
     1081 tcttttcgct ttgtgtgggg tatcacttgg tggtcaaatt gtcatggaac ttttatctcg
     1141 aaaacctaat attactaaaa aagcaattat tgatggtagt atttgctacc caagacctct
     1201 tatggcaagg ttttgtattg ctggtattcg attttttgga ggacttttgt ttagtgagaa
     1261 ggcttgtcgc tttcaaattg ctatgatgcc aaaattgtta cctgaaaata tgcaatatcc
     1321 agatgaaata aaagcgtatt atatgacaga tatgccacat gtaagaaaag aaacattcta
     1381 taatatgtat cgtacttaca tgatgaacta tacacttaaa gagaatgtta aaaaaaccac
     1441 agcacaagta atgtactggt atggagaaaa agaaatgaag tgtgtcaaaa aatctgcaaa
     1501 actgtttcag tcttatgtgc cctcttgtga gatttatgaa gctaagagct ataatcatgg
     1561 gtatttatca ctttatcttc caaatgaatg gttggaaatt gcagaaccat ttttccaaaa
     1621 ggaataaagg tgttaggtga ttattgtata attattgctg tttttttata tagtaaataa
     1681 attaggtata aatataaaaa attattttag ttaatatatt agtgaaagct taataggaaa
     1741 attataaata gattaaaggt agcacctata taaatagttg ctaccttttt ctgtttgtaa
     1801 ataaatgata gataagaagg tttactgaca aatcactgac taaacccaat tttcttacat
     1861 tgaaagcctt aattttactt gttttaaata aatttacaat ttcttgttat aaaatactaa
     1921 attttgttaa caattataat tagcatttaa tttatactgg aggtttatat gattagtgta
     1981 agaacagatt tagctttaga agctagtgaa atgtgtgaaa agtctcaaga aggaagtagt
     2041 attcctggtg taaaaataga aactaaagaa ttagaaaatt gcattgtaac taaagttgaa
     2101 gtaatagaca ggcaaggcgc agagataatg aataaagata taggaaagta tataactctg
     2161 gaaagtaatc ttatgaagtt tgatgatgat gagtcaagag aagaaatgat aagttattta
     2221 aaagaggagt tagtagatat atttggccaa gacaaaaata aaaaaaccct ggtaattggt
     2281 cttggaaata gaaatattac ttctgatgcg ttaggaccaa agagtgtatc aaaaacactt
     2341 gtaactagac atctttttaa aaattataat aaagactatg atgatgattt cactgaggta
     2401 tcagctttaa gcccaggagt tatgggtgtt actggaatag aaactagtga aatagtaaaa
     2461 tcattggttg agaaggttaa gccagataga gtagtagcaa tagatgcatt ggcttcaaga
     2521 aaaatggaga gagtaaactc tactatacag atatcaacag caggaatatc acctggtgga
     2581 ggtgttggca atactagaaa atctctaact aaagaaactt taggcgtgga tgttattgca
     2641 ataggcgttc caacggtggt tgatgcagca actcttacaa tagatgtctt agatatggca
     2701 atagacaatt taatagctca atcagaagaa acagaaagtt tttatgaaat gttgaaaaaa
     2761 cttaaagaag aagaaaaata tcatctaata aaagattcgt tagacccata tgacaagaac
     2821 ttaatagtaa caccaaagga tatagatgat acaatcgaaa atctatctat aataataagt
     2881 gaaggcttaa ataggtcttt acatccaggt agattggtat aaaataagga ggagcaatta
     2941 tgtttaaaaa atgcattaaa gtagtaacct tgacttttat attagtatgc attttaccag
     3001 gaaaatcatt agctttgaat caagatgatt ttttaaagtt tttagtaaat tcatcttatc
     3061 cagaagctaa agtcgaagga aatgatacag aaaataaaaa gaataataaa aataaagaaa
     3121 caagtaagga aaataaggaa gaaagtaaag aaggaaacac taaatctaaa gatgcaagta
     3181 aagttgataa taaaaaagag agtgaaaaag aatatataaa actttatgtt ggtaaagaaa
     3241 atgttccaga tattgagtca aaaaattcag acacaactga aactaacaca acatctagtt
     3301 cagattataa ggatgattta agagtaacca aagaaaatcc aagaattttg atatatcata
     3361 ctcatggatg tgagacttat tcaaattcac ctgatggaaa ttatcattca agagataaga
     3421 aaaattcagt aatggaagta ggaagtgcat taactagtgc tttagatagc aaaggatggg
     3481 gtgtagtcca tactactaaa taccatgact atccatctta taataactct tatgcaagta
     3541 gcttaaaaac aatacaaagt atattaccta aatataactc agtggatata gcgatagact
     3601 tacatagaga tgctagggat ttaactaatc cagccactaa ggaaaaagac catttaaaat
     3661 atacaactat gataaatgga gagagagtat caaagttctt ctttgttgta ggaggtaaaa
     3721 atacaaatag aaaacaactt agagctttag cagaagatat aactgctttt gctgagaaaa
     3781 agtatcctgg tctagtatct ccaatagtag aaaaagacta tgctagattc aatcagtttg
     3841 cagttaagaa tcatatgtta gtagaaatag ggaataacgc aacaagtgta gaagaatcta
     3901 aggctactac aaagtattta gccgagattt tggatgaata ttttaaacaa aaaaattaga
     3961 gctttaagtt ataattagga gcatgctaaa tgagccgatt agaaaaaaat atagaaagta
     4021 aaagtaaact aagaaaatac aagtatatta tgagaatctt atttttgatt actatgatta
     4081 tatgtacatc agtttgtgta tttatagtgg acagtaatgc aaaaagtatg ctaggaatga
     4141 aacaatatga ttttccaagt attaaatttg atataacaaa atttgatttt gacataccaa
     4201 attttgatat acatgaaatc ataaaaaaat ttaataagta gtaataagtg aataaggttt
     4261 attgattaaa ataagcctta ttttagttat atatttttaa tgtataaaat aaaaattcat
     4321 taactgtatt ttataggatt tactttaagt ttatgatatt atataatatt tagtgttaga
     4381 cttgataatc cacatataat gtggataatt ttgtttagtg ccaattagtt tatattcaaa
     4441 aattttaaat ttggtatata aagagttttt agataatgta aaataataac tataagaata
     4501 atcaagagga gggaatttta aggtggacaa taaacaaagt agaactagaa attttagtat
     4561 aattgcacat atagaccatg gaaagtctac cttagctgat agattaatac aacaaactgg
     4621 gcttgttagt gaaagagaca tgaaaagtca attacttgac aatatggacc ttgaaagaga
     4681 aagaggaatc actataaagc ttcaaaacat aagattaatg tataaagcga aggatggaaa
     4741 tgaatattat ttaaatctta tagatacacc tggacatgta gactttaact atgaggtatc
     4801 aagaagttta gctgcatgtg aaggagcact attagtagtt gatgcagctc aaggtgttga
     4861 ggcacaaact ttagccaatg tttatcttgc tatagaccaa gatttagaaa tattaccaat
     4921 aataaataaa atagatttac caagtgcaag accagaggaa gtaaaaaatg aaatagaaga
     4981 tttaataggg cttgattcaa gtgaagctcc tcttatttca gctaaaactg gtttaaacat
     5041 agaagatgtt ttagaagata ttgtaaaaaa tgttcctcca cctaaaggag ataatgaagc
     5101 tccattaaag gcattaatat tcgattctta ctatgatgct tacaaaggtg ttgtagctta
     5161 tgttagagta tttgaaggaa ctgttaaaaa gggtatgaca ataaaaatga tgaataccaa
     5221 taaaaagttt gaggtaactg aagttggtgt tatggctcca ggtcaaactg aacttagtga
     5281 attatcagca ggtgatgttg gttatattgc tgctagtata aaagatataa gaagttgtcg
     5341 tgttggtgat acaataacag attcaaataa tcctacagaa gaacctttac caggatacaa
     5401 aaaagctact ccaatggtat attgtggtat atatccagga gaaggagaaa agtatgagaa
     5461 tgttagagat gctcttgaaa agcttcaagt aaatgatgct gcacttgaat atgaagctga
     5521 gacttcagca gcactaggat ttggttttag atgtggtttc ttaggtcttt tacatatgga
     5581 gataatgcaa gaaagacttg agagagaatt taaccttgat ataattacta cagctccatc
     5641 tgttatatat agagttacaa aaatggatgg agaggttgta atgatacaaa atcctgcaaa
     5701 cttaccagaa ccatctgaga taaagatgat agaagagcct atagtaaaag gagatataat
     5761 agttcctaaa gactatgtgg gtgttgttat ggagctttgc caggaaagac gtggaaatat
     5821 gttaaatatg gaatatatag atgatagaag agtaatgctt cactatgacc ttcctctcaa
     5881 tgaagttgtt tacgatttct ttgatgcttt aaaatcaaga actagaggtt atggttctct
     5941 tgattatgag gttaaaggtt atgtagcatc tacacttgta aaacttgata tattaatcaa
     6001 taaagagcaa gtggatgcac ttagttttat tgtccatgag acacgtgctt tccctagagg
     6061 aaaggcaatg tgtgagaaat taaaaggaga aattccaaga catcagtttg ctataccaat
     6121 acaagctgct gttggtaata aggttattgc aagagaaaca ataagcgctc taagaaaaga
     6181 tgttcttgct aaatgttatg gtggagatat atctcgtaag aagaaacttc ttgaaaaaca
     6241 aaaagaaggt aagaagcgta tgagacaaat tggttctgtt gaagttcctc aaaaagcatt
     6301 tatgtctgtg cttaaattag atgagtaaat ccttataaat ttagataaag atatttaaaa
     6361 gctagagtga ttttagaatt atttctaaat tagtctagct tttttatggt atattttaag
     6421 taaactcata gagaatataa gtaagaatat taaagaagaa taaaaaggtg atatttatga
     6481 ttaatataga aattcctaaa aaagtagact atataattaa agaattagaa aagaatggtt
     6541 atgaagctta tatagttgga ggatgtgtta gagattgttt attagaaaga gttccaaacg
     6601 attgggatat aacaactagt gctagaccag aagtggtagt agaattattt gaaaaaacaa
     6661 ttccaactgg tatacaacat gggactgtaa cagttatgat tgaacatgaa ccatttgaag
     6721 tgacgactta tagaattgat ggaaattata gtgatggtag acatccagat tcaatagaat
     6781 ttacaaataa catagttaag gacttgtcaa gaagagattt tactatcaat tcaattgcat
     6841 acaattcaaa gacaggatta gtcgacccat ttaatggcta tgaagatata caaaataagt
     6901 atatacgttg tgttggaaat ccagtagata gatttgaaga agatgcactt agaatgctta
     6961 gagcagttag attttcagca caactcaatt ttaaaatagc tgaaggtact aagcaaagta
     7021 ttcataaaaa agcagatttg ataaaaaatg tttctattga aagaatccag acagagttta
     7081 ataaaatatt agtatctgat tcatctaaat taaacttatt aaaatcaaca ggtttgttga
     7141 aatttataat tcctgaaata tgtgaattag aagatgttac tcaacacaat ccatatcaca
     7201 tctatgatgt acaaaaacat actttaatag ctacagaagt aattgaagat gaactgtatt
     7261 taaaacttac aatgttgttt catgatttag gtaaaaaagt aactaaaaca actgataaaa
     7321 atggtgttga ccatttttat actcatagta gagaatctgt aaagattgca aagaagattt
     7381 tgaaaagact taagtatgat aattatacta ttaataaagt tttaatatta atacaatatc
     7441 atgattatag aatagaacct aaaaggaaga taattaaaaa gttattaaat aaacttgaag
     7501 atgttgaatt atttgaagat ttaataaaag ttaattgggc tgatacactt gcaaaaaatc
     7561 caaagtatgc aaaacaaaag atattaaatc ttattgagtg tgaaaaagaa tttaaacata
     7621 taataaatca aaaggagtgc tttaatctta aagatttagc tattaatgga aaagatttga
     7681 tatctatagg tataaaacca ggtaaagata taggatatat tttaaataag atgcttgaaa
     7741 tagtcataaa taatccagag ttaaatgaaa aagaaatact aaaagaaaaa gcattaaata
     7801 tatatacatt ttagattcaa atataaaaaa tttaattact ttaaaaaaca tagaataaaa
     7861 tacttattta gataaaataa ataattttta gagaatattt tagaagttac gattgtatga
     7921 tttttaaatg cataggcatt tactctagga ctatagacta atataaaaaa aaactttggg
     7981 aatactaaaa ccataaattt ataaaattaa tattttatat actgtaaaac agtgaggagg
     8041 gacagtatgc atactcaact acaaaagact attggtcttt cagcagctct ttctactgtt
     8101 gtaggtatgg ttataggttc gggagttttt tttaagccac aagcaatata cactacaact
     8161 aatggagctc caggtctagg tattatagcg tggcttttag gtggttttat aacaataact
     8221 gctgggctta cagctacaga aatttcagct gctataccaa aaactggtgg tatgatgatt
     8281 tatatcgaag aaatatatgg agaaaagtta ggttttttaa ctggatggat gcaaactgta
     8341 ttatttttcc caggtacatc agcggcatta ggagtaatat ttgctcaaca agcatctgaa
     8401 cttttaggaa tgagcccaaa taatatggca aatgtacttc ctatagcaat tggagttata
     8461 ctatttttag cgttattaaa tataataggt tcatccttag gaggaaaagt tcagacagta
     8521 gccactattg gaaagatgat acctttaatt ttaataatag tctttggatt tattaaaggt
     8581 caaagtagtg aagtattaaa tccatttgta ggagatggtg taaatgcatc aaatgcactt
     8641 ggacaagtat taatagctac tttgtttgca tatgatggtt ggataaatgt tggagctata
     8701 tcaggagaaa tgaagtctcc agagaaagat ttaccaagag caatagttgg tggtttatca
     8761 ttagttatgg cagtttatat tataataaat atagcttatc tttgggtagt accagcaagt
     8821 gaattagcaa cagttacttc cccagctaca ttagtagcaa caagattgtt tggaaatata
     8881 ggtggaaaag taataactgt gggtatatta atatcagtat ttgggacatt gaatggatat
     8941 ttattaacag gttcaaggat accttataca ttagctgaaa tgggaacttt accagcatct
     9001 aaaactcttt taaaagtaaa ttctggaggt tctcctgtaa attcaatact acttataact
     9061 gtgttagcct gtgtatatgc attatctggt caatttaatc ttttgacaga cttaacaata
     9121 ttttcaatat gggtatttta tgtattgact tttataggtg ttatgaggct tagaagacaa
     9181 aagccagatt tacacagacc atataaagtc cctttatatc caataatacc aattatagct
     9241 atattaggtg gactgtttgt aataataaat caaatattga cttcaacagt catatcttta
     9301 ggcggaatat ttataacact attaggttta ccagtttatt attatatgaa aaaaagataa
     9361 ctacttaatt taagttagat aaatttgggt aaaggtgaaa attaactttt atccaaattt
     9421 tttatactgt tatacaatat aagtattata tattgcttga tgtgctattt tgtttgattt
     9481 ataatttagt aattgatgtt ttaagataat ttaagaaatg aggagtgaaa gatgctagga
     9541 ctttatgtac atattccatt ttgtgtgaaa aaatgtaagt attgtgattt taattcttat
     9601 aaaatggaca tagattcaaa aaaaagatat atagaagact taaaaataga aatggaatta
     9661 tatagtaata aattatataa agataataaa tataaaaata aagaatgctg tagtctaaat
     9721 aaaaatgaca aaataacgag tatatttgta gggggaggta cacctagtat actaacctct
     9781 gatgaaataa gagaagtatt tataagtata aaagaaatgt ttgatataga tgagaatgca
     9841 gaaataacta tagagtgtaa tcctgggaca ttaacattag aaaaattaaa aactatgaaa
     9901 gagattggca taaatagact tagtataggg ctacaagcta ttcaagaaaa gcatttgaac
     9961 tttataggaa gaatacatac ttatgaagaa tttgagaaaa actataaaga tgcattaagt
    10021 gtaggtttta aaaatattaa tatagattta atgtacagtc ttccaaatca aactctatgt
    10081 gattggaagg aaactcttga aaaagttgta cacttaaatc caacacatat atcagcttat
    10141 tcccttatac tagaagaagg aactgaacta tacaatatgt atgaaagtaa taaatttgaa
    10201 cttatagatg aaaatgtaga tatagaaatg tatgagtata caataaacta cttaaagtca
    10261 aaaggatata atcaatatga aatatccaac tactcaaaag aaggctataa ttgtgagcat
    10321 aatattttat attgggaatg tgaacattat atagggattg gagcaggagc ttctggctat
    10381 attaatgaga acagatacaa taatgtagaa tctttagaag attatcattt aagtttggta
    10441 aaaagagaaa aaccaataca agaaaatgaa attctttctg agaaagatat gatagaagaa
    10501 aagatattta tggggcttag aatgaataaa ggcataaaat ttgaagattt taaaaaaaaa
    10561 tttggaatag attttagaga gaagtataat aagcaaatag aaatgctatt agctagaaag
    10621 cttataaatc agagctttga aggtatacaa ttaactcaaa aaggaagaga aatatctaat
    10681 agtgtattta tagaatttat ggaataattt ttaaggtgtt gacaaaataa atttataatg
    10741 gtatataata tatataatct ttttagcact cgaacttagt gagtgctaac agctaggagg
    10801 tataataata tggaattaaa tgaaagaaaa ttaaatatcc tcaaagctat agttaaagat
    10861 tatatagaaa cagctgaagc tataggttct agaacaatat ctaaaagaca tgatttaggt
    10921 gttagtgctg ctaccataag aaatgaaatg gctgaccttg aagaattagg gtatttaatt
    10981 cagcctcata cttctgcggg tagagttcca tctgaaaaag gctataagtt atatgtaaac
    11041 tctcttatga gtaaaagcga attggatgat aatgataaga ttcttattga acaatgtatg
    11101 aatcacaata taaatcatat aaaagaattg attcatgaaa cttctaagct attatcgcaa
    11161 ctaacaaact atacaactgt agcagttact aagagtttaa taaatcaaag tgttataaag
    11221 cacatacagt tggttgctat gaatgacaat aatattttac ttatagttgt aacagataaa
    11281 ggggacttaa aaaaagctaa ccttacaact aatgtatatt tagatcaatc taagttaaat
    11341 ttgatttctg ataatcttac aaggaagctc ttaggtaaaa gtataacaga tttggatgat
    11401 aatctaattg cttttattaa atacgaaata agtgagtatt ctgggcttat agatgagctt
    11461 ttaaatgctt tgaactcaaa tatgaaagaa gaagattttt ctctatcatt aaatggagct
    11521 actaacatat ttagttatcc agaatttaat gatgtattaa aagcaaagtc atttttaaat
    11581 atgttggaaa aaaaggaaac aatagctgac ataattaaat caaagggaat acaaaaagac
    11641 aatctaaata taataattgg tagtgataat gattgtgaac tggcacagga ttgtagtata
    11701 gttacagcaa cttataatgt agatagagac ttggttgggc gaataagctt tataggccct
    11761 accagaatgg attatgctag aatttactct ataataaatt atatgagttt attaattaat
    11821 agaaagtaaa gaaattttaa attgcgaggt gtaaagtctt ggataaaaaa aatgagcaac
    11881 aggaagtaag agaagaaaat gatacttcta ttaaccaaga atcggaaact caagtagagt
    11941 tagaagagga agttgttaat gaagaatgtg aaacatcaag tgaaaaaact gatgaaaaag
    12001 aagttgatga tgaaaatgta acagatataa attctaagtt agcagaaaaa aaattgcagg
    12061 atgagttgga tgaattaaat gataaatatc aaagacttca agccgaatat gcaaactaca
    12121 gaagaagaac tcaacaagag aaagagacaa taggcgtatt tgcaaatgaa aaaataataa
    12181 ctgaattgat accagttata gatagtatgg aaagagcctt agatgcatgt gaagataagg
    12241 aagatactat gtataagggt ataagccttg tacataaaca attaatagac actttagtaa
    12301 aatttggagt agaagaaata gaagcagaat ctaaggaatt tgaccctaat ctacatctag
    12361 cagttatgca agaaagtgta gatggagttg aagcaaatca aatagtaatg gtacttcaaa
    12421 aaggatataa gctaggaact aaagttgtaa gaccttcaat ggttaaagtt tcttgctaag
    12481 tataaattaa aggttaaatt atttaaccta atataaaata ttaaaataag taaaacttaa
    12541 ttatataatt actcgaggag gattttagtc atgggaaaaa taataggaat agatttagga
    12601 acaacaaatt catgtgttgc agtgttagaa ggtggagaag cacaaataat agcaaatagt
    12661 gaaggtatga gaactactcc atcagtagta gcatttacaa aagatggtga aagaatagtt
    12721 ggagaacctg caaaaagaca agcagttaca aatgcagata aaacaataac ttctataaaa
    12781 actcatatgg gaactgatta taaagtaaat atagatggaa aatcatatac tccacaagaa
    12841 atatcagcaa taatattaca aaaattaaaa tcagatgcag aaagttactt aggacaaaca
    12901 gtaacagaag cagttataac agtaccagct tactttacag atgctcaaag acaagcaact
    12961 aaagatgctg gtagaatagc agggcttgat gttaagagaa taataaatga gccaacagca
    13021 gcagctcttg cttatggtat ggataaatta gaccaagaaa agaaaatatt agtatttgac
    13081 ttaggtggag gaacttttga cgtatctata cttgaaatag gagatggaac ttttgaagtt
    13141 ttagctacag ctggtaacaa tagattaggt ggagatgact ttgaccaaat agtaatagat
    13201 tatttagcag aggaatttaa aaaagctgaa ggtgtagatt taagaaatga taaaatggct
    13261 cttcaaagat taaaagaagc agcagaaaag gctaagaaag aattatcatc aacaatgagt
    13321 tcaaacataa acttaccttt cataactgct acagcagaag gaccaaaaca cttaaatata
    13381 gatttatcaa gagctaaatt tgaagaatta actagaggtt tagttgaaaa aactatggaa
    13441 ccaactaaga cagctttaca agatgcagga ctttctacag gtgatataga tgatgtatta
    13501 ttagtaggtg gttctacaag aataccagca gtacaagaag ctgttaagaa gtttatagga
    13561 aaagaacctc ataaaggtat aaacccagat gagtgtgttg cagcaggtgc ttctatacaa
    13621 gctggagttt tagcagggga tgttaaagac ttattattac tagatgttac tccattatct
    13681 cttggtatag aaactatggg taatgtaatg actaagataa tagaaagaaa tactacaata
    13741 ccaactaaga agtctcaaat attctcaact gctgctgata accaaacagc tgttgatata
    13801 catgttcttc aaggtgaaag aagtatggct tatgacaata caactttagg aagattccaa
    13861 ttaacagata taccaccagc acaaagagga atacctcaaa tagaagttac ttttgatata
    13921 gatgcaaatg gtatagttaa tgtttcagct aaagatttag gtacaggaaa agagcaaaaa
    13981 ataactataa catcaaacac taatttatca gaatcagaaa tagagcaaaa gataaaagaa
    14041 gcagaaatga atgcagaagc tgacaaacaa aagaaagaaa aaatagaagc attcaatcaa
    14101 gctgaatcta ctatatatca aactgaaaaa actttaaatg aacttggaga taaaataagt
    14161 tcaggtgaaa aagaggatat agaaaaagct atagcagact taaaagctgt aaaagataat
    14221 caagatgcta cagcagaaga acttaagaaa gctacagatg aagtaatgac taagttccaa
    14281 aaagtatctc aagaaatgta ccaaaaagca gctcaagaac aacaagcggc acaaggtgca
    14341 gaacaagcac aagacaatgg acctaaagat gacaatgtag tagatgctga ctttaaagaa
    14401 gtagatgaag ataaataagc tatataatat gtaacactaa atgataattg gaacatatat
    14461 gatttgtgaa aatcatatag atgttaaaga tatatggaca atatacatca taaagaatat
    14521 aatatatcat agattatata acttaaagta gaatataaga attaatgata gcttgtagtt
    14581 tattattcta caagctatcg ttttgtaaaa tgaaggtggt gtcaattttt gagtacaaaa
    14641 agggattatt atgaagtctt aggtatcagt aaaggtgcag aagctcaaga gataaaaaaa
    14701 gcttatagaa aattagcaat gaagtaccat ccagatagaa atcctggaga taaagaggcg
    14761 gaagaaaaat ttaaagagat aaatgaagct tatgaagttc tatctgatga tacaaagaga
    14821 aaaacttatg accagtttgg acatgatggg ctaaatggtc aaggcggttt tggtggtcaa
    14881 ggaggatttg gcggtcaagg ctttggtggt tttgaagata tgttcggaga tatatttggt
    14941 gacatgtttg gaggaagctt cggaggtgga agagcaagaa gaagagggcc tcaacgtggt
    15001 gcagatataa gacagagtgt tactatatct tttgaagaag ctgcatttgg taaaaagatg
    15061 tctataaaag taaatagaag tgaagaatgt gaagaatgta atggaactgg agcaaaacca
    15121 ggaacatcaa agaaaacttg ttcaacttgt aatggaactg gtcaagttag aactgttcaa
    15181 agaactccat ttggtaatat agcaagttca agaccatgta gtgcttgtaa tggaactgga
    15241 gaagtgattg aatctccatg tagtaaatgt catggaactg gaaatacaag aaaagttaag
    15301 actatagaag tagatatacc tgctggtata gatgatggtc aaatgataaa actttctggt
    15361 caaggtgaag taggagaaaa aggtgctcca agaggagact tatatattgt agttaatgtt
    15421 aagtcacatc cactatttac tagagatgga aatgatattt attttgaaat gccaattaca
    15481 tttgttcaag caactttagg tgatgagata gaagtaccta ctttggatgg aaaagttaaa
    15541 tatagtgtgc cagaggggac acaaactgga actgtattta gacttaaaga gaaaggaatc
    15601 cctagaatta gaggtaattc aagaggagac caatatgtta aggttgtagt tgaaattcct
    15661 aaaaaattaa acgataagca aaaagaacta ttgagagaat ttgcgaagga gtgtgggtcg
    15721 aacgtccacg aaaagaagaa aaccttcgga caaaagatag aagatatgtt taagaaaaag
    15781 tagttaaagt agccaatata taatcatatt tttaaaatct tagttattta taagattgtc
    15841 aaaggagata ttatgatttt tatattggct atttttgtat aaaaaataaa tgtgcataaa
    15901 ataaaactga atataaataa ttttctgaaa aatacttgtc ctaaaatata taatatgcta
    15961 taatataatc aaataaaaga aaggggtgat tccagtggga acggatgtgg cactgccaaa
    16021 tgatgaagaa aactttattg taatatacaa aataaaatta gatactttta gtgctagatt
    16081 aagtactgga aaaactcatg agctgggata attattgtaa ttacctagac tcaaactttt
    16141 agtagtaaaa tagtaatatt atatagacaa ggtatctaat ttttaaatct tttgtatgaa
    16201 ttaaaatttt tataaagggt atatctgatt agaatgtaat tagggaaacc tagttgtgaa
    16261 ttacttttag tatatacatg tgtaaagaaa tatgtatatg gtattgggta ttgtgctaga
    16321 tgtgtatgta aaggaatatg tgtctagttg ggtatatgta aagaaatata cttataatct
    16381 atgaaaaatt tttagtataa attgctaaaa cattgagatt gttttttata gaaagttagt
    16441 ttataccaac taaaaatgtg cttaagattt gtttgatgtt taattataaa taaggttgta
    16501 gataaaaaaa taagtaaaga caaaggttta aaatacttgc tttaaatata gtttgttttg
    16561 aacacttgcc aaattaaaat aattaataaa atagacatct tctcatagta aaatatactg
    16621 tgagaggatg tttttgcttt gttcataaac ttttatgaaa aatttgcata gtgtcacatt
    16681 ttaatatact atatatataa taaaatatag ataaaattaa atgattcaaa agagaaaggt
    16741 gaaaagagat gtattatata ggtgtagaca taggaggaac aggtatacaa gcaggagtag
    16801 ttgataacta tgggaagata atttttaggt cagagtgtaa aacagtaatt gaaaaaggat
    16861 ttgaaggaat acttaatgac ataaaaataa tgatttataa gttgttggaa gataataaac
    16921 ttactatgag tgacataaaa tctattggat ttggtgttcc aggttttata aataaagaag
    16981 gattagtaac ttgtgtaaat ttaaaatgga ataaaaaagc ttttaataaa gagttaaaaa
    17041 aaagatttcc agatgttgaa attcatggag aaaatgatgc aacagtagca gcacttggag
    17101 aagcaaagtt tggaagtatg aaaggtgcta atgttggagt attatatact ttaggaactg
    17161 gtgtaggtgg aggaatagta attaatcaaa aagtcttttc tggagcacat ggattgggtt
    17221 cagaaatagg tcatcaaatt ataggagaaa actattttaa ttgtaattgt ggaaataatg
    17281 gttgtgtaga aactttttgt tcagcaactg caattataaa gtattctcaa aaactgatag
    17341 aagaaggaga aaagagtagg attttagatt tggcagaggg aaatttagaa aatgtaaatg
    17401 caaagatggt gtttgatgca tatagagaaa atgatttagt ggcaattaaa gtaataaata
    17461 gatttaaaga gtatttagca aaaacttttg caaacacaat aaattcttta gacccagaaa
    17521 ttatatctat aggaggaggc atttctaaat ctagcgatat aatacttgat ggaatagaag
    17581 gtttggtaag aaaatttgta ttatacaaaa cagaagatat agctacaatt acatgtgcaa
    17641 ctttaggttc agacgcagga attataggag cagctttttt ataatgtaaa tgaactgctt
    17701 attggaggcg tgatgatata tgggtaaaac aaatgctaga agaacgcttt ttttgatagc
    17761 aataggttca ggaactatgc tgaatcctct taattcttct atgatttcac ttgctttaca
    17821 tagtatacaa aatgattttc atattagttt tacaactgta tcttggattg tttcagcatt
    17881 ttacctagct agtgctattg cacaaccagt ttcaggtaag ataggagatt taataggtag
    17941 aaaggtctta tttttgagtg gtttgatgct tgtaatttta tcagcatcca tagtaccact
    18001 tgttcaatca ttctttatat tgatttttat aagagtaatt caagcaattg gaacaagtac
    18061 cctatatcca tctggagttg ctcttataca aaataatata aaagaaagac aatcttctgc
    18121 attagcagtt ctaaccattt ttgcttcaac tacagcagga ttaggtccga cacttggagg
    18181 attattgttg gacttaggag gatggcatgc tatatttctt gtaaatatac ctgttgtttt
    18241 ggtttctata tgcttagggt attttttatt cccaaaagaa gtaaaagaaa agaaatctat
    18301 aaaagaaact ttaaaaaatg ttttgtcaag attagatatt attggcatac ttctattttc
    18361 aattgcaatg atttttatat tactattttt gctatctatg aaggaatctt ttaacttaga
    18421 acaacttgta tttggtataa tactgatgtg tctttttatt tggcatgaat tgagaacaaa
    18481 attgccattt atagatatta agctttttgt aagtaatcct aaattgtcaa aagtttactt
    18541 gcaatttatt atattaaatt tctttaatta tattttgttt tttggtcttc ctagttattt
    18601 tcaagatgcc ttacattata gtgcaaagtc gactggatta tttatgctat ttatgtctgg
    18661 tataggtata tttatatctc cattaactgg aaaatggata gataaatctg gaactagatt
    18721 tcctcttgtt acatcatcaa tctttatgtt tattagtgca gtacttcttt cagtagtttt
    18781 tatccatata cctgtaatag gaaagggtat tatattatca ttagcaggta ttagttatgg
    18841 agttggtaat gtagccctgc aatcctctat gtttgaagaa agtcctcgtg acagtatagg
    18901 gacagcttct ggtctgtttc aaactagtcg ttatttaggt tctattttag caactgtttt
    18961 acttggaatg gtatttgaag taaatataac atcagaacaa tttcagatat taggttatgt
    19021 tatggtggtc ttaggtacaa taagtttttt attaaatttt atattaaaga aagaattaag
    19081 aaaagtagaa tagtggattt atggatttaa taagtctaat aactgataag tttaaaaata
    19141 ttgtttgtaa aacataactg gtttgatatt tattaattct aagttttgaa gcatagagta
    19201 ctcgataagt atacaatatt ttgaattaaa attaagcaga aatttgaact agtctttcaa
    19261 atctctgctt aatttagtag ttaaattttt ttatagagaa aataagattt gacacttaga
    19321 taaaaaatca ttgcattttc aaaattcttt aaatcaaacc caagtatctc attaatcttt
    19381 tccaatctat atactagcgt gtttctatgt aaaaacatac tagtagatgt cttagaaata
    19441 tttaaatcat tatttataaa ttttattcct gtatatagaa gttcttcgtc aatagattta
    19501 atcttattaa aatctattaa tttattgagt atattatcct cattaattaa atctaaagtt
    19561 ttatatctaa taaggtcaaa caaatttaaa aacttatttt cagcgttgtc ttttataata
    19621 tgaggtagta aatcagaaca taactgtaat ctaaaatcaa aatcagcttt actatctaat
    19681 tcaccaagat aaaaaatata agtactttga taagtttcag tttcaattat attttgtgta
    19741 gttacattaa tatctaagtt atatttagaa tttactataa aaaaaccatt gtgttgtatt
    19801 atatttatat cttcaaataa attataaaaa atatttttta gatattcaaa gtctatatga
    19861 gattggtaaa ttaaataaaa gttgcctttt aaattatcga gattattttt atctagaaaa
    19921 tcaataacat aaatagcatt attgaaagta actaaatggc tactagcatc taacttttgg
    19981 ttttcatatg gatagatatt tattttttta ttaagctgtc tttctaaaaa atcttttaac
    20041 tcttccataa agtctcctta aaaataagat tatattctta tcttatagct aaagtagttt
    20101 ctttgtcaaa tatgtgtact ctactattgt caactgaaag tgttaagtca tcaccaacat
    20161 taattctgtt tttactgtca aatctaattg ttatcgtatt ttcgcctagt tttaagtgag
    20221 cataagtttc tgctcccata agttctttta tttcaattct tgatttaaaa caagtatctg
    20281 gattagattt aataaaagta tcttctacat gaatatcttc tggtctgata cctataacaa
    20341 cttcattatt aatataattg tcttttatta aatcatagtg tttttcttta ttcaatttaa
    20401 gcttaatatg ttcattttgt gcataaattt catcattttc ttctattaat attacatcaa
    20461 taaaattcat ctgtggtgct ccaataaatc ctgcaacaaa tatattagct ggataatcgt
    20521 atacatcttg tggagttgca atctgctgaa ctactccatc cttcattact acgattctat
    20581 cagccatagt catagcttca acttggtcgt gtgttacata gataaatgta gttccaagct
    20641 gttggtgtag cttagttatc tctgttctca tagcagttct aagttttgca tctaagttgg
    20701 atagaggttc atccattaag aataccttag gatttctaac tattgcacgt cctaaggcaa
    20761 ccctttgtct ttgtcctcca gataatgttt taggtttttt atttaaaaga ggtagtaagt
    20821 ctaatatttt agcagcttct ttaacttttt tgtctatttc atctttaggc aattttctaa
    20881 gtttaagtgc aaatgccatg ttttcgtaaa cagataagtg gggatataaa gcatagtttt
    20941 gaaaaaccat agctatatct ctatcttttg gttctatatc attgacaagt ttatctccaa
    21001 tgtatagttc tccttcagag atttcttcaa gaccagcaat cattctaagt gtagtcgatt
    21061 taccacaacc agatggtcct actaaaacga taaattcttt atctttaatg tctatattta
    21121 tattttttac tgcattaaat ccatttgagt aaagttttga tatatttttt aaaattactt
    21181 ctgacataat atcctccttg atatttaaat tttaattata tagtatcaaa tttttttatt
    21241 atattaaatg tgtaaaatga ctaaatgt
//
LOCUS       DAMJVG010000066        20793 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.066, whole genome shotgun sequence.
ACCESSION   DAMJVG010000066 DAMJVG010000000
VERSION     DAMJVG010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20793)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20793)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20793
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.066"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            370..681
                     /gene="rpsJ"
                     /locus_tag="PC512_002690"
     CDS             370..681
                     /gene="rpsJ"
                     /locus_tag="PC512_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HDF2442424.1"
                     /translation="MAKNEKIRIRLKSYDHKLLDFSAGKIVETAKKAGSQVSGPVPLP
                     TEKQVVTILRAVHKYKDSREQFEIRTHKRLIDIANPTPKTVDSLMRLDLPAGVDIEIK
                     L"
     gene            773..1402
                     /gene="rplC"
                     /locus_tag="PC512_002691"
     CDS             773..1402
                     /gene="rplC"
                     /locus_tag="PC512_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HDF2442425.1"
                     /translation="MKGILGKKVGMTQIFTDKGVVIPVTAVEAGPMVVTQIKTVDKDG
                     YNAIQIGFEDAKEKALNKPKKGHLAAANVLKKHLKEFRVDSVEGYTVGQEIKADVFEA
                     GAKIDVTGISKGKGFQGPIKRHGQSRGPETHGSRYHRRPGSMGACSYPGRVFKNKKLA
                     GHMGSVKVTVQNLEVVKVDADKNLILVKGAIPGAKGSVVTIKEAIKVSK"
     gene            1432..2055
                     /gene="rplD"
                     /locus_tag="PC512_002692"
     CDS             1432..2055
                     /gene="rplD"
                     /locus_tag="PC512_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001127258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HDF2442426.1"
                     /translation="MPKLNVLNVSGQNVGEIELSDSIFGVEVNGHVLYEVVKNQLANK
                     RQGTQSAKTRAEVRGGGRKPWKQKGTGRARQGSTRSVQWVGGGVAFAPKPRSYKYTLP
                     KKVRRLAMKSALSSKVQNSEVIVLDALNMDAPKTKEFAQILNNINAAKKALVVIADKN
                     DNVIKSARNIEGVQTALVNTMNVYDILKYDSFIITTDAVKKVEEVYA"
     gene            2055..2345
                     /gene="rplW"
                     /locus_tag="PC512_002693"
     CDS             2055..2345
                     /gene="rplW"
                     /locus_tag="PC512_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HDF2442427.1"
                     /translation="MTNPHDVIIRPVVTEHSMAEMGEKKYTFVVAKDANKTEIKKAVE
                     KVFGVSVDKVNTLNYDGKVKRMGRTQGRTSSFKKAVVKLTADSKEIEFFQGM"
     gene            2375..3205
                     /gene="rplB"
                     /locus_tag="PC512_002694"
     CDS             2375..3205
                     /gene="rplB"
                     /locus_tag="PC512_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HDF2442428.1"
                     /translation="MAIKKFRPTSPALRQMTVLVSDEITCNQPEKSLLVNLKKNAGRN
                     VHGRITVRHRGGGQKRKYRIIDFKRDKDGIPAKVATIEYDPNRTANIALLNYADGEKR
                     YILAPVGINVGDTILSGLGADIKPGNCLALKDMPVGTIIHNIELKPGKGAQLVRSAGV
                     SAQLMAKEGKNALLRLPSGEMRLVSINCKATIGQVGNIEHGNVVIGKAGRKRHMGIRP
                     TVRGSVMNPNDHPHGGGEGRSPIGRPSPVTPWGKPALGYKTRKKNKASNKLIVSRRTK
                     "
     gene            3240..3521
                     /gene="rpsS"
                     /locus_tag="PC512_002695"
     CDS             3240..3521
                     /gene="rpsS"
                     /locus_tag="PC512_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003454422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HDF2442429.1"
                     /translation="MSRSTKKGPFVHARLLKKIEAMNASGNKEVIKTWSRSSTVFPQM
                     VENTIAVHDGRKHVPVYITEDMVGHKLGEFVPTRTFKGHKDDEKSNKRK"
     gene            3553..3888
                     /gene="rplV"
                     /locus_tag="PC512_002696"
     CDS             3553..3888
                     /gene="rplV"
                     /locus_tag="PC512_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HDF2442430.1"
                     /translation="MEAKATAKYVRVSPRKAGQICDLVRGKNVDEALAILKFTPRGAA
                     SIIAKVVKSAKANAENNHEMDTEKLYIASIVANQGPTMKRFMPRAMGRATTIRKRTSH
                     IEVVVKEKK"
     gene            3911..4726
                     /gene="rpsC"
                     /locus_tag="PC512_002697"
     CDS             3911..4726
                     /gene="rpsC"
                     /locus_tag="PC512_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HDF2442431.1"
                     /translation="MGQKVNPHGLRVGVIKDWDSRWFATDKKEFGNLLLEDHNIRKFL
                     KKRLYSAGVAKIEIERSANKIKMDLHVAKPGVVIGRAGAGIEALKAELEKMTKKTIIV
                     NIVEVRSTDKNAQLVAENIALAIERRVAFRRAMKQAIQRAMKSGAKGIKVSASGRLGG
                     AEMARTEGYSEGNVPLQTLRADIDYGFAEADTTYGKIGIKVWICNGEVLPTRDGVNPR
                     EESRKSDRRDNKRDNRRNDRRGNDRRGNDNRGNYRGQRPQGGSRPQRTENKGN"
     gene            4762..5193
                     /gene="rplP"
                     /locus_tag="PC512_002698"
     CDS             4762..5193
                     /gene="rplP"
                     /locus_tag="PC512_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HDF2442432.1"
                     /translation="MLMPKRVKRRRVHRGSMAGQAHKGNKVTYGEFGLVALEASWITS
                     NQIEAARIAMTRYIKRGGKVWIKIFPHKPVTRKPAETRMGAGKGSPEYWVAVVKPGRV
                     MFELAGVSEDKAREAMRLAAHKLPIKCKFVKKEDLEVKGGE"
     gene            5195..5398
                     /gene="rpmC"
                     /locus_tag="PC512_002699"
     CDS             5195..5398
                     /gene="rpmC"
                     /locus_tag="PC512_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005810148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HDF2442433.1"
                     /translation="MKAKELRDLTSEELMNKLNDFKSELFSLRFQLATGQLENTARIK
                     FVKKDIAKVKTVLAERKLYETRA"
     gene            5422..5676
                     /gene="rpsQ"
                     /locus_tag="PC512_002700"
     CDS             5422..5676
                     /gene="rpsQ"
                     /locus_tag="PC512_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HDF2442434.1"
                     /translation="MERGRRKVRIGRVVSDKMDKTIVVAVEEFVRHPLYNKRVKRTKK
                     FKAHDEKNICNIGDRVKIMETRPLSKDKRFRLVEVVEKVK"
     gene            5702..6070
                     /gene="rplN"
                     /locus_tag="PC512_002701"
     CDS             5702..6070
                     /gene="rplN"
                     /locus_tag="PC512_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007885948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HDF2442435.1"
                     /translation="MIQQESRLRVADNSGAKELLCIRVLGGSKRRYGNIGDVIVATVK
                     SATPGGVVKKGKVVKAVIVRSKQGVRRNDGSYISFDENAAVIIKDDKTPVGTRIFGPV
                     ARELRDNEFMKIVSLAPEVL"
     gene            6094..6399
                     /gene="rplX"
                     /locus_tag="PC512_002702"
     CDS             6094..6399
                     /gene="rplX"
                     /locus_tag="PC512_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HDF2442436.1"
                     /translation="MRVKKGDTVVVIAGKDKGKKGSVLKVYPKTSKVLVEGVNVITKH
                     QKPSAMNQQGGIINKEAPIHISNVMPFDPETGKGVRVRYEVKDGNKVRVSAKSGKEL"
     gene            6429..6971
                     /gene="rplE"
                     /locus_tag="PC512_002703"
     CDS             6429..6971
                     /gene="rplE"
                     /locus_tag="PC512_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HDF2442437.1"
                     /translation="MASRLQEKYMKEVAPALMEKFGYKNVMEIPKLNKIVINMGIGDA
                     RENPKGLEKGVEELEMISGQKPVITKARKSVANFKLREGMPIGTKVTLRADKMFYFMD
                     KLVSVSLPRVRDFRGVNPNAFDGRGNYALGVKEQLIFPEIEYDKIDKVRGMDIIFVTT
                     AKTDEEARELLKLLGMPFSK"
     gene            6989..7174
                     /locus_tag="PC512_002704"
     CDS             6989..7174
                     /locus_tag="PC512_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HDF2442438.1"
                     /translation="MARKAMVVKQQRKQKYATREYTRCTICGRPHSVLKKFGICRICF
                     RELAYKGQIPGVRKASW"
     gene            7207..7605
                     /gene="rpsH"
                     /locus_tag="PC512_002705"
     CDS             7207..7605
                     /gene="rpsH"
                     /locus_tag="PC512_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HDF2442439.1"
                     /translation="MTMTDPIADMLTRIRNANVVKHETVDVPASNMKKELARILLEEG
                     FIRGYDVIEDGKQGIIRIQLKYGQEGERVITGLKKISKPGMRVYAANHEIPKVLNGLG
                     ISVISTSKGILTDKQARKENVGGEVICYVW"
     gene            7636..8178
                     /gene="rplF"
                     /locus_tag="PC512_002706"
     CDS             7636..8178
                     /gene="rplF"
                     /locus_tag="PC512_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HDF2442440.1"
                     /translation="MSRIGVKPIIIPAGVEVTIAEGNLVTVKGPKGTLTKQLSAELNI
                     KKEENTIMVERPTDNKKHRSLHGLTRTLLDNMVVGVNTGFEKKLELKGVGYRAQKQGK
                     KLVMNLGFSHPVEMEDPEGITVEAPNQTELIVKGIDKQLVGNYAAKIRAWRKPEPYKG
                     KGIKYVDEVIRRKEGKTGKK"
     gene            8214..8582
                     /gene="rplR"
                     /locus_tag="PC512_002707"
     CDS             8214..8582
                     /gene="rplR"
                     /locus_tag="PC512_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HDF2442441.1"
                     /translation="MLKKADKNANRLQRHKRVRRKISGTSQRPRLCVFRSANNIYAQI
                     IDDTKRVTLVAASSLEAEVKSAVNHTGNKEAAKKVGELVAKKAVEKGITEVVFDRGGY
                     LYHGRIQELAEGAREAGLKF"
     gene            8603..9112
                     /gene="rpsE"
                     /locus_tag="PC512_002708"
     CDS             8603..9112
                     /gene="rpsE"
                     /locus_tag="PC512_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011109776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HDF2442442.1"
                     /translation="MLRRKPIDAGQLDLQEKVVEVRRVTKVVKGGRNFRFAALVVVGD
                     ENGHVGIGAGKAMEVPDAIKKAVEDAKKNLIVVPIVGTTIPHEVRGHFGAGNILIMPA
                     VEGTGVIAGGPARAVLELAGLKDVRAKSLGSNNPRNMVNATIEGLNSLKTVEDIAKLR
                     GKKVEELLG"
     gene            9127..9312
                     /gene="rpmD"
                     /locus_tag="PC512_002709"
     CDS             9127..9312
                     /gene="rpmD"
                     /locus_tag="PC512_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HDF2442443.1"
                     /translation="MAKLQIKLVRSVIGTTPNQKKNVEALGLRKREQVVVKEDNAQTR
                     GMINKVSHLLEVTEIAE"
     gene            9345..9788
                     /gene="rplO"
                     /locus_tag="PC512_002710"
     CDS             9345..9788
                     /gene="rplO"
                     /locus_tag="PC512_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HDF2442444.1"
                     /translation="MKLHELKPAEGAVRAKRRLGRGTATGQGKTAGRGQKGQWSRSGG
                     GVRVGFEGGQMPLARRLPKRGFNNIFKKVYTEVNVEVLNRFENGTEITAELLKSTKTI
                     SKIGKDGIKILGEGNLEKALTVKAAKFTASAQEKIEKAGGKAELV"
     gene            9832..11100
                     /gene="secY"
                     /locus_tag="PC512_002711"
     CDS             9832..11100
                     /gene="secY"
                     /locus_tag="PC512_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HDF2442445.1"
                     /translation="MLSKLKQAWKIKAVRKKVMYTLMMIVIFRIGTTIPVPGIDTSII
                     QKMVGGNSLLSLYNMFTGGAFSNFSLFALGISPYITASIIIQLLTVGFESLAELQKSG
                     EEGKKKINKYTKYTALALAVVQALGITLGIVRSALISNSVFFITTVVITLVSASMLVM
                     WIGDKITEKGIGNGSSVIIFAGIISRIPTDVIKISQQVKSGEVAPWVIVILAVVILLT
                     VTGVTFIQEATRKIPVQYAKRVVGRKMYGGQSSHIPMKVNQSGVMPIIFASSLLAFPQ
                     TIAMFMGPNAQAFVQKYLSMATEQGFWTYRSIEILLIIFFSYFYTTVSFNTEDISKNM
                     KNNGGFIPGIRPGEPTMDYLNRILTRLTLAGATFLAIIAMVPALTTHYMKVNMSLAGT
                     SLLIVVGVALELKRQLESNLVMRSYQGFLK"
     gene            11117..11767
                     /locus_tag="PC512_002712"
     CDS             11117..11767
                     /locus_tag="PC512_002712"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HDF2442446.1"
                     /translation="MRIILLGPPGAGKGTQAAGIVEKYNIPHISTGDIFRKNIKEGTE
                     LGKKAKEYMDQGLLVPDELTVGLVTDRISQEDCKNGFMLDGFPRNVAQGEHLDIFLKN
                     AGISLDKVVNIEVDKSILVSRAVGRRICKSCGATYHVEFNPPKVEGVCDVCQGELYQR
                     ADDNEETVSKRIQVYLDETKPLVDYYSKQGIIADIKGDQAIDKVFEDIVAALGSGK"
     gene            11768..12514
                     /gene="map"
                     /locus_tag="PC512_002713"
     CDS             11768..12514
                     /gene="map"
                     /locus_tag="PC512_002713"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HDF2442447.1"
                     /translation="MIILKSKKEIELLREAGKIVADTHEVLRKAISPGISTLELDKIA
                     EENIRKYNAEPSFKGYGGFPGSICASINREVVHGIPGETILQEGDIVSLDIGAYYKGY
                     HGDSAKTHGVGMISEEDRKLIEVTRESFYEGIKFAKLGYRLSDISHAVQTHVEKHGFS
                     VVRDLVGHGVGANLHEDPQVPNYGLPGKGPRLREGMVIAIEPMVNAGRYHVKTLSDGW
                     TTVTIDGKKSAHYEHTIAITEHEPLILTKL"
     gene            12536..12805
                     /locus_tag="PC512_002714"
     CDS             12536..12805
                     /locus_tag="PC512_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KOW domain-containing protein"
                     /protein_id="HDF2442448.1"
                     /translation="MLSDNLSIGQVVKVSLGRDKGNLFFVVKIINNEYVLIADGKKRK
                     LDKPKLKKVKHLKKYNFINDEVRKRVVSGQEITDSFLRAELTKLN"
     gene            12843..13061
                     /gene="infA"
                     /locus_tag="PC512_002715"
     CDS             12843..13061
                     /gene="infA"
                     /locus_tag="PC512_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001029884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HDF2442449.1"
                     /translation="MAKKDVIELEGTVSEALPNAMFKVKLENGHEILCHISGKLRMNF
                     IRILEGDKVNVELSPYDLTRGRITWRKK"
     gene            13097..13210
                     /gene="rpmJ"
                     /locus_tag="PC512_002716"
     CDS             13097..13210
                     /gene="rpmJ"
                     /locus_tag="PC512_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HDF2442450.1"
                     /translation="MKVRPSVKPICEKCKVIKRKGKVMVICENPKHKQKQG"
     gene            13363..13734
                     /gene="rpsM"
                     /locus_tag="PC512_002717"
     CDS             13363..13734
                     /gene="rpsM"
                     /locus_tag="PC512_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005810116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HDF2442451.1"
                     /translation="MARIAGVDLPREKRAEIGLTYIYGIGKATANEILAKAEINPDTR
                     IKDLSEDQVNELRKVIDDDFLVEGDLRREIALNIKRLRDIKCYRGIRHAKGLPLRGQR
                     TKTNARTRKGPRKTVSRKKKK"
     gene            13770..14168
                     /gene="rpsK"
                     /locus_tag="PC512_002718"
     CDS             13770..14168
                     /gene="rpsK"
                     /locus_tag="PC512_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HDF2442452.1"
                     /translation="MAKPKKKVTRIRRRERKNIERGHAHIQSTFNNTIITLTDVHGNA
                     ISWASSGQLGFKGSRKSTPFASQMAAETAAKAAMEHGLKSVEVFVKGPGSGREAAIRA
                     LQATGLEVTMIKDVTPIPHNGCRPPKRRRV"
     gene            14200..14823
                     /gene="rpsD"
                     /locus_tag="PC512_002719"
     CDS             14200..14823
                     /gene="rpsD"
                     /locus_tag="PC512_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HDF2442453.1"
                     /translation="MARYTGASCRQCRREGMKLFLKGDRCYTDKCAIVKRNYAPGQHG
                     QGRKKVSNYGLQLREKQKVKRIYGVLETQFRNLYERAENMPGKAGENLLSLLERRLDN
                     VVYRMGLASSRKEARQLVTHGHFTLNGNKVDIPSLIVKVGDVIEVKEKSRSSAKFKNL
                     VEVNSRIAPKWLEANVEGMTAKVVGVPTREDIDLEIAEHLIIELYSK"
     gene            14901..15848
                     /locus_tag="PC512_002720"
     CDS             14901..15848
                     /locus_tag="PC512_002720"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HDF2442454.1"
                     /translation="MIEIEKPKVDIVELSEDYRYGKFVIEPLERGYGITIGNALRRIL
                     LSSLPGVAVNAIKIDGVLHEFSTIPGVKEDVTEIILTLKELSATIDGEGSRTLKIEAQ
                     GPCSITGADIICPPDVEILSKDLAIATLDDNAKLNMEIFVDKGRGYVSAEENKTENVP
                     IGVLPVDSIYTPVEKVSYHVENTRVGQKTDYDKLVLEVWTNGSINPQEGISLAAKVLV
                     EHLNLFIDLTEHVSSVEIMVEKEEDQKEKVLEMTIEELDLSVRSYNCLKRAGINTVEE
                     LANKSEDDMMKVRNLGKKSLEEVIQKLEELGLGLKPSEE"
     gene            15869..16210
                     /gene="rplQ"
                     /locus_tag="PC512_002721"
     CDS             15869..16210
                     /gene="rplQ"
                     /locus_tag="PC512_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003357477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HDF2442455.1"
                     /translation="MAKYRKLGRETAHRNLMLRNLVTCLLRSGRIETTVTRAKETRRM
                     AEKMITLAKRGDLHARRQVLAYVMDETVVNNLFTDLAPKYAERNGGYTRIIKIGPRKG
                     DAAEMAFIELV"
     gene            16330..17163
                     /locus_tag="PC512_002722"
     CDS             16330..17163
                     /locus_tag="PC512_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HDF2442456.1"
                     /translation="MDNIVKVNNISFEYITDEAKLKAIDNLSLDVKKGEFVAIIGHNG
                     SGKSTLSKNLNAILMPTEGNILIDDMDTKEEERLWDIRQTAGMVFQNPDNQIVATIVE
                     EDVAFGPENLGIEPKEIRRIVEESLKSVGMYDLRDRQPHLLSGGQKQRVAIAGIIAMR
                     PKCIIFDEATAMLDPSGRKEVMKTIKRLNKEENITVIHITHFMEEAVEADRVVVMEKG
                     KKILEGTPREVFSKIKMLKEIGLDVPCMTELSSLLIEEGINISSDILTVDEMVMELCQ
                     L"
     gene            17151..18017
                     /locus_tag="PC512_002723"
     CDS             17151..18017
                     /locus_tag="PC512_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HDF2442457.1"
                     /translation="MSIIVKNLTHIYNEGMPFASKALDDVSFEIKDRDFVGLIGHTGS
                     GKSTLIQHLNGLLKPSSGEIFINDFNITDKNLNLTEIRKRVGVVFQYPEYQLFEETID
                     KDIAFGPSNLGLEESEIHNRVKASMEAVGLDYEGFKDKSPFELSGGQKRRVAIAGVIA
                     MNPEVLILDEPTAGLDPGGRDEIFNLIKDLHEKKNMTIILSSHSMDDMAKLAKTLIVM
                     NHGSVEFMGTPREVFKSNASKLKDIGLDIPQVLELALKLREKGFDISEDILTLEEAKQ
                     EILKVVRGRGLC"
     gene            18011..18814
                     /locus_tag="PC512_002724"
     CDS             18011..18814
                     /locus_tag="PC512_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HDF2442458.1"
                     /translation="MLKDITIGQYYPTSSAIHKLDPRIKLVATIVFMVSIFVVNKFWP
                     YIVVLLCLLAMIKLANIPVKYIVKGVKPLKWIILFTFLINIFFLPGDEIWSFGFLAIT
                     KQGLRQAIFMAIRLIFLVVGTSLLTLTTSPIELTDGIERLLNPFKKIGLPVHELAMMM
                     TIALRFIPTLLDETDKIMKAQMSRGADFESKNLINRAKNLVPLLVPLFVSAFRRADEL
                     AMAMEARCYRGGHNRTKMRESVISRRDYMACVFQVVYLGAIIATRFIAI"
     gene            18846..19577
                     /gene="truA"
                     /locus_tag="PC512_002725"
     CDS             18846..19577
                     /gene="truA"
                     /locus_tag="PC512_002725"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003514691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HDF2442459.1"
                     /translation="MRNIKIKIQYNGKNYCGWQKQPDSLGIQGTIERAIYDITKEETS
                     LIGSGRTDSGVHAIGQIANFKINSGISIESIPMALNAKLPKDISVIEACEVNDDFHSR
                     YSAKGKTYKYLVYNSKFRNPILSEISYQVKYELDFDKMCSEAKSLLGTHDFKGFMSSG
                     SSVKDTVRTIYDIDISKKDDLITFEISGNGFLYNMVRIIVGTLVDMGRGRINEPFLDI
                     IQSKTRSRCGHTAPAQGLFLKKVHY"
     gene            19697..20128
                     /gene="rplM"
                     /locus_tag="PC512_002726"
     CDS             19697..20128
                     /gene="rplM"
                     /locus_tag="PC512_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HDF2442460.1"
                     /translation="MKSYIAKPADVQRKWYLVDAEGKTLGRLATEIATVLRGKHKPTF
                     TPHVDGGDFVVVVNAEKIVLSGKKLDQKYYRYHTGYVGGLKEISYRDMMDKKPEEVIS
                     HAVSGMLPKNKLRSRMMTRLRVFAGAEHTHAAQNPEVLNFK"
     gene            20157..20549
                     /gene="rpsI"
                     /locus_tag="PC512_002727"
     CDS             20157..20549
                     /gene="rpsI"
                     /locus_tag="PC512_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003515879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HDF2442461.1"
                     /translation="MANVQYYGTGRRKSSVARVRLVAGEGNILVNGRALENYFNYETL
                     IRDVKQPLVLTGNENKYDVIVKVEGGGFTGQAGAIRHGISRALLKADLDLRPALKKEG
                     FLTRDARMKERKKYGLKAARRAPQFSKR"
BASE COUNT         8304 a         2448 c         4328 g         5713 t
ORIGIN      
        1 ctttactaaa ctaatggatt taatataaaa aaagaggggg gtaactcctc tcttttttgt
       61 tttttgttga caagtagcgc taaagcatat atactaaact agtgccttga gacagattaa
      121 caatcaagtt taaggttatg atgttgtaat agaaaataaa attgaaaaaa acagaaaaaa
      181 aacttgaaaa aatgtaacag atgatataaa atataatagt gtgcttgaga gattaagaaa
      241 ataataatta aatcctagtg aaatacgaac tgatatcgat ttaaaagtta caacacaccc
      301 ggagcagtgt atcggtattg gttgtacgca acttgaaaat taaacacgtg ataaaggagg
      361 gaaaacaaaa tggctaagaa tgaaaaaata agaataagat taaaatcata tgatcacaaa
      421 ttattagatt tttcagcagg taaaatagtt gaaactgcta aaaaggctgg atcacaagtt
      481 tcaggacctg tgcctctacc aacagaaaaa caagttgtaa ctatattaag agctgtacat
      541 aagtacaaag actctagaga acaatttgaa ataagaactc ataaaagact aatcgacata
      601 gctaatccaa cacctaagac agttgactca ttaatgagat tagacttacc agcaggtgta
      661 gatatagaaa taaaattata agaaccccta agatattatc ctatagatga ttatcttaga
      721 atgattactc taaaagatgt aatccgctgt aagaattata ggaggtgcta atatgaaagg
      781 aatattaggc aaaaaagttg gtatgactca aatattcact gataaaggtg tagttatacc
      841 tgtaacagct gttgaagcag ggcctatggt cgttactcaa ataaaaacag ttgataaaga
      901 tggatacaat gctatacaaa taggttttga agatgctaaa gaaaaagctt taaacaaacc
      961 taaaaaagga catttagctg ctgctaatgt tttaaagaaa catttaaaag aatttagagt
     1021 agattctgta gaaggataca cagtaggaca agaaataaaa gctgatgtat ttgaagcagg
     1081 tgcaaaaata gatgttactg gaataagtaa aggtaaggga ttccaaggtc caataaaaag
     1141 acatggacaa agtagaggtc ctgaaactca cggttctaga taccacagaa gaccaggttc
     1201 aatgggagct tgttcttacc caggtagagt atttaaaaac aaaaaattag ctggacatat
     1261 gggaagcgta aaggtaacag ttcaaaactt agaggttgtt aaagtagatg ctgacaagaa
     1321 ccttatatta gttaaaggag ctataccagg agctaaaggt tcagtagtaa ctataaaaga
     1381 agctataaag gtttctaaat aatgactaac ctagagaaag gaggaataac aatgccaaaa
     1441 ttaaatgtac taaatgttag tggacaaaac gttggagaaa tagaattatc agattctata
     1501 tttggcgtag aagttaatgg acatgtttta tacgaagttg taaaaaatca attagcaaat
     1561 aagagacaag gaactcaatc tgctaaaact agagcagaag ttagaggtgg cggaagaaaa
     1621 ccttggaaac aaaaaggaac aggtagagca agacaaggtt ctacaagatc tgtacaatgg
     1681 gtaggtggag gagttgcttt tgcacctaaa ccaagaagct acaaatatac attacctaag
     1741 aaggtaagaa gattagctat gaagagtgct ttatcttcaa aagttcaaaa tagtgaagtt
     1801 atagtattag atgcattaaa catggatgct cctaagacta aagaatttgc tcaaatatta
     1861 aacaatataa atgctgctaa aaaagcttta gtagttatag ctgacaaaaa cgataacgta
     1921 ataaaatcag ctagaaatat agaaggtgtt caaactgcat tagttaatac tatgaatgta
     1981 tatgatatat taaaatacga ttcatttata ataactacag atgctgttaa aaaagtggag
     2041 gaggtgtacg cataatgact aatccacatg atgtaataat aagaccagtt gtaactgagc
     2101 acagtatggc tgaaatgggt gaaaaaaaat acacttttgt tgtggctaaa gatgcgaaca
     2161 aaactgaaat aaaaaaagca gtagaaaaag tattcggagt tagtgttgat aaagtaaata
     2221 ctttaaacta cgatggaaaa gttaaaagaa tgggtagaac tcaaggaaga acatcaagct
     2281 ttaagaaagc agtagttaaa ttaactgctg atagtaaaga aatagaattc ttccaaggaa
     2341 tgtagtatta taacaaacga aggagggaaa acagatggct ataaaaaagt ttagaccaac
     2401 ttctcctgcc ttaagacaaa tgacagtttt agtttctgat gaaataacat gtaatcaacc
     2461 agaaaaatct cttttagtta acttaaagaa aaatgctggt agaaacgtac atggtagaat
     2521 aactgttcgt catagaggtg gaggacaaaa aagaaaatat agaataatag attttaaaag
     2581 agataaagat ggtatacctg ctaaggttgc tactatagaa tatgatccaa acagaactgc
     2641 aaatatcgca ttattaaact atgctgatgg agaaaaaaga tatatattag ctccagttgg
     2701 aattaatgtt ggagatacta tattatcagg attaggtgct gatataaaac caggaaactg
     2761 tttagcatta aaagatatgc cagttggtac tatcattcat aatatagaat taaagccagg
     2821 aaaaggagct caattagtta gatctgctgg agtttctgca caattaatgg ctaaagaagg
     2881 aaaaaatgct ttattaagat taccatcagg tgagatgaga ttagtaagca taaactgtaa
     2941 agctactata ggtcaagttg gaaatataga gcatggtaac gtagttatcg gtaaagcagg
     3001 tagaaaaaga catatgggaa taagacctac tgtaagaggt tctgtaatga accctaatga
     3061 ccatccacac ggtggagggg aaggtagatc tccaataggt agaccatctc ctgttactcc
     3121 atggggtaaa ccagctcttg gatacaaaac tagaaagaaa aataaagctt caaataaact
     3181 aatagtatca agaagaacta agtagtaaat ttatttttgc tcggaaagga ggaatataaa
     3241 tgtcaagatc aactaaaaaa gggccttttg tccatgcaag acttttaaag aagatagaag
     3301 ctatgaatgc tagtggaaat aaagaagtta taaaaacttg gtcaagatct tcaactgtat
     3361 ttccacaaat ggtagaaaac actatagctg ttcatgatgg aagaaaacat gttccagtat
     3421 atataacaga agatatggtt ggacataaat taggtgagtt cgttcctact agaactttca
     3481 aaggacataa ggatgacgaa aaatctaata agagaaaata attaaattat gactaagaaa
     3541 ggaggaataa caatggaagc aaaagctact gctaaatacg tacgtgtatc accaagaaaa
     3601 gcaggccaaa tatgtgacct tgttagagga aagaatgttg atgaagcatt agcaatatta
     3661 aagtttactc caagaggagc agcttcaata atagctaagg ttgtaaaatc agctaaagct
     3721 aacgcagaaa acaatcacga aatggatact gaaaaattat atatagcatc aatagttgct
     3781 aatcaaggac caacaatgaa gagattcatg cctagagcta tgggtcgtgc aactacaata
     3841 agaaaaagaa cttctcatat agaggttgtt gttaaagaaa aaaaataatt aatagatagg
     3901 agggaaagta atgggtcaaa aggttaatcc acacggctta agggtcggtg ttataaaaga
     3961 ttgggactca agatggttcg ctactgataa aaaagagttc ggaaacttat tattagaaga
     4021 ccataatata cgtaaattct taaagaaaag attatactca gctggagttg ctaagataga
     4081 aatagaaaga tcagctaaca aaataaaaat ggacttacac gttgctaagc ctggtgtagt
     4141 tataggaaga gctggtgcag gaatcgaagc attaaaagct gaattagaaa aaatgacaaa
     4201 gaaaactata atagttaata tagtagaagt aagaagtaca gataaaaatg ctcaattagt
     4261 agctgaaaat atagctttag ctatagagag aagggttgct ttcagaagag caatgaaaca
     4321 agctatacaa agagcaatga aatctggtgc taaagggata aaagtttctg cttcaggaag
     4381 attaggtgga gctgaaatgg ctagaactga aggttatagt gaaggaaatg tgccactaca
     4441 aactttaaga gcagatatag attatggttt cgctgaagct gatacaactt atggaaaaat
     4501 cggtataaaa gtttggatat gtaatggtga agttttacca actagagacg gtgtaaatcc
     4561 aagagaagaa agcagaaaga gcgatagaag agacaacaag agagataata gaagaaacga
     4621 tagaagagga aatgacagaa gaggaaatga taacagagga aactacagag gacaaagacc
     4681 tcaaggtgga tcaagacctc aaagaactga aaacaaagga aattaataat agttaggttc
     4741 aaggaaggag gaaaaatact catgttaatg ccaaaaagag taaagcgtcg tagagttcat
     4801 agaggaagca tggctgggca agctcataag ggtaataaag ttacttatgg tgagtttgga
     4861 ttagtagcat tagaagcttc ttggataact tctaatcaaa tagaagctgc cagaatcgcg
     4921 atgactagat atataaaaag agggggaaag gtttggataa aaatattccc tcataaacca
     4981 gtaacaagaa aaccagcaga gactcgtatg ggtgcaggga aaggttctcc agaatattgg
     5041 gtagctgtag ttaagccagg aagagttatg tttgaattag caggtgtttc tgaagataaa
     5101 gcaagagaag ctatgagact tgctgcacat aaattaccaa tcaaatgtaa atttgttaaa
     5161 aaagaagatt tagaagtaaa gggtggtgaa taggatgaaa gctaaagaat taagagattt
     5221 aacaagcgaa gagctaatga acaaattaaa cgacttcaaa agtgaattat ttagcttaag
     5281 attccaatta gctactggtc aattagaaaa tacagctaga ataaagtttg ttaagaagga
     5341 tatagcaaaa gttaaaactg ttcttgctga aagaaagtta tacgaaacta gagcttaatt
     5401 tggaaaggag gctttttaaa catggaaaga ggaagaagaa aagttagaat aggccgtgtt
     5461 gttagtgata agatggataa aacaatagta gtagctgttg aagaattcgt acgtcatcca
     5521 ctatataata aacgtgttaa gagaactaag aaattcaagg ctcatgatga aaagaatata
     5581 tgtaacatcg gagatagagt taaaataatg gaaactagac cattatctaa agataagaga
     5641 ttcagactag ttgaagttgt tgagaaagtt aagtagtttt tgaagaagga gggattacga
     5701 tatgatacaa caagaatcac gtctaagagt tgctgataac tcaggagcta aagaactttt
     5761 atgtatacgt gttctaggcg gaagtaaaag aagatatggt aacataggcg acgttatagt
     5821 tgctactgtt aaaagtgcaa cacctggtgg agttgtaaaa aaaggtaagg ttgttaaagc
     5881 tgttatagta agaagcaaac aaggcgtaag acgtaatgac ggaagctata tatcttttga
     5941 tgaaaatgct gctgttataa taaaggacga taaaactcca gtaggaactc gtatattcgg
     6001 gcctgttgct agagagttaa gagacaatga attcatgaaa atagtttctc ttgctccaga
     6061 agtactataa ttaaggaggt gcaataggac atgatgcgtg ttaaaaaagg tgacactgtt
     6121 gtagttatag caggtaaaga taaaggtaaa aaaggttcag ttttaaaggt atatcctaaa
     6181 actagcaaag tgttagttga aggtgtaaat gtaataacta aacatcaaaa accaagtgct
     6241 atgaaccaac aaggtggaat aataaataaa gaagccccaa tacacatatc taatgtaatg
     6301 ccatttgatc ctgaaacagg aaaaggcgtt agagtaagat atgaagtaaa agatgggaac
     6361 aaagtaagag tatcagcaaa gagcggaaaa gaattataat aaatattgct tgaaaggagg
     6421 gaccttaaat ggcttctaga ttacaagaaa aatacatgaa agaagttgct cctgctttaa
     6481 tggagaaatt tggatacaaa aacgtaatgg agatacctaa gttaaataaa atagttatta
     6541 acatgggtat aggtgacgct agagaaaatc caaaaggatt agaaaaaggc gttgaagaat
     6601 tagaaatgat atcaggacaa aagcctgtta taactaaagc tagaaaatct gttgctaact
     6661 tcaaattaag agaaggaatg ccaataggaa caaaagttac attaagagct gacaaaatgt
     6721 tctacttcat ggacaaatta gtttcagttt ctttaccaag agttagagac tttagaggag
     6781 ttaaccctaa tgcttttgat ggtagaggaa attatgcttt aggagttaaa gaacaattaa
     6841 tattccctga aatagaatat gataaaatag ataaagtaag aggaatggat ataatatttg
     6901 ttactacagc aaaaactgac gaagaagctc gtgaattatt aaaattatta ggaatgccat
     6961 tttctaagta agcaaaggag ggattcccgt ggctagaaaa gcgatggttg ttaagcaaca
     7021 aagaaagcaa aagtacgcta ctagagaata cactagatgt actatatgcg gaagaccgca
     7081 ttcagttttg aaaaaatttg gtatatgccg tatatgcttt agagaattag cttataaagg
     7141 tcaaatacct ggtgttagaa aagcaagctg gtagaagctt gattagaatg gaaggagggc
     7201 aacaaaatga caatgacaga tccaattgca gatatgctta ctcgtataag aaatgctaat
     7261 gttgttaagc atgaaactgt agatgttcca gcttctaata tgaagaaaga attagctaga
     7321 atcttattag aagaaggttt cataagaggt tatgatgtta tagaagatgg aaaacaaggt
     7381 atcataagaa tacaattaaa gtacggacaa gaaggcgaaa gagttataac aggtcttaag
     7441 aaaatatcta agcctggaat gagagtttac gctgctaacc atgagatacc aaaagtatta
     7501 aacggattag gaatatcagt tatatctact tcaaaaggaa tattaactga caagcaagct
     7561 agaaaagaaa atgttggtgg agaagtaatc tgctacgttt ggtaattaat atgaacaatg
     7621 taaggaggtg cgaccatgtc aagaataggt gttaagccaa taataatacc agcaggtgtt
     7681 gaagttacta tagctgaagg aaatttagtt acagtaaaag gtccaaaagg aactttaact
     7741 aaacaattaa gtgctgagtt aaacataaaa aaagaagaaa atacaataat ggttgaaaga
     7801 ccaactgata ataaaaaaca tagatcttta cacggactaa ctagaacttt attagataat
     7861 atggttgtag gtgtaaatac tggtttcgaa aagaaattag aattaaaagg tgttggatat
     7921 agagctcaaa aacaaggaaa gaaattagtt atgaacttag gtttctctca tccagttgag
     7981 atggaagatc cagaaggaat aactgttgaa gctccaaacc aaacagagtt aatagtaaaa
     8041 ggtatagaca agcaattagt agggaattat gctgctaaga taagagcttg gagaaagcca
     8101 gagccataca aaggtaaagg tataaaatac gttgatgaag taatcagacg taaagaagga
     8161 aaaactggta aaaaataata ccaaaactta aacgctagaa aggagtgagc taggtgttaa
     8221 aaaaggctga taaaaatgct aatagacttc aaagacataa gagagttcgt agaaaaataa
     8281 gcggtacttc tcaaagacca agattatgtg tatttagaag tgctaacaat atatatgctc
     8341 aaataataga tgacacaaaa agagtaactc tagttgctgc atcttcttta gaagcagaag
     8401 ttaagagtgc tgtcaatcat acaggaaaca aggaagcagc taagaaagtt ggagaattag
     8461 ttgctaaaaa agctgttgaa aaaggaatca ctgaagttgt atttgacaga ggtggatact
     8521 tatatcatgg aagaattcaa gaattagctg aaggtgctag agaagctggt cttaagttct
     8581 aatacgaagg agggaaaaat acatgctacg tcgtaagccg atagatgcag gacaacttga
     8641 cttacaagaa aaagttgttg aagtaagacg tgttactaag gttgtaaaag gtggtagaaa
     8701 tttcagattt gcagcattag tagttgttgg agatgaaaac ggacacgttg gtataggtgc
     8761 tgggaaagca atggaagtac cagacgctat aaaaaaagca gttgaagatg ctaagaaaaa
     8821 tctaatagta gtgccaatag ttgggactac aattcctcac gaagtacgcg gacactttgg
     8881 tgctggaaat atattaataa tgcctgctgt agaaggtaca ggagtaatag ctgggggacc
     8941 tgctagagcc gtacttgagc tagctggact aaaagacgtt agagctaaat ctttagggtc
     9001 taacaatcca agaaatatgg taaatgctac aatagaagga cttaattctc taaaaacagt
     9061 tgaagatata gctaaactta gaggtaaaaa agttgaagaa cttctagggt aaggaggtag
     9121 tgtaaaatgg ctaaattaca aataaagtta gttagaagtg ttataggaac tactcctaac
     9181 caaaaaaaga atgttgaagc gttaggatta agaaaaagag aacaagttgt tgtaaaagaa
     9241 gacaatgctc aaacaagagg tatgataaat aaagtaagtc acttattaga agtaactgaa
     9301 atagctgaat aatttttata aagtagtgca aggaggtgca atccatgaag ttacatgagt
     9361 taaaacctgc tgaaggtgca gtaagagcta agagaagatt aggtagaggt actgcaactg
     9421 gacaaggtaa aactgcagga cgtggacaaa aaggtcaatg gtctcgttct ggtggtggag
     9481 taagagtagg atttgaaggt ggacaaatgc cactagctag aagacttcct aagagaggtt
     9541 tcaataacat atttaagaaa gtttacacag aagttaatgt tgaagtttta aacagatttg
     9601 aaaatggaac agaaataact gcagaattat taaaatctac taaaactata agcaaaatag
     9661 gtaaagacgg aattaaaatc ttaggtgaag gtaatttaga gaaagcttta actgttaaag
     9721 ctgctaaatt tacagcttca gctcaagaaa aaatagaaaa agctggtgga aaagcagagt
     9781 tagtataata acctgctaat ctcctagcca gtacaggcgg ggtgaattag cgtgctgtca
     9841 aaattaaaac aagcttggaa gattaaagca gtaagaaaaa aagtaatgta tacacttatg
     9901 atgatcgtga tattcagaat aggtactact ataccagttc caggcataga cactagtatt
     9961 atacaaaaga tggtaggcgg caatagtcta ctttctctgt ataatatgtt tactggtgga
    10021 gcatttagta acttttcact atttgcttta ggtataagtc catatatcac tgcatcaatc
    10081 ataatacaac ttctaacagt aggttttgaa agtttagcag aacttcaaaa atctggtgaa
    10141 gaaggaaaga aaaaaatcaa taagtacact aaatatacag cactagctct agcagttgta
    10201 caagctttgg gaattacatt aggaattgta agaagtgctt taatatcaaa tagtgtgttt
    10261 tttatcacaa ctgttgtaat aacattagtt tcagcaagta tgttagtaat gtggattggg
    10321 gacaaaatta ctgaaaaagg aatcggtaat ggtagttcag taataatatt tgcaggtata
    10381 atatcaagaa tacctacaga tgttattaaa atatcgcaac aagttaaatc tggcgaagtt
    10441 gcaccttggg ttatagtgat tctagctgta gttatattac ttacagtaac aggagttaca
    10501 tttatacaag aagcaactag aaagatacct gtacaatatg ctaaaagagt tgttggaaga
    10561 aaaatgtatg gaggacaaag ttctcatata ccaatgaaag ttaaccagtc aggagttatg
    10621 cctataattt ttgctagttc acttttagct ttccctcaaa caatagctat gtttatgggt
    10681 ccaaatgctc aggcttttgt tcaaaaatac ttaagtatgg caacagaaca aggattttgg
    10741 acatatagat caattgagat tctacttata attttcttct catattttta tacaactgta
    10801 tcatttaata cagaagacat atctaaaaat atgaaaaata atggtggatt tataccaggt
    10861 ataagaccag gtgagcctac tatggattat ttaaatagaa ttttaactag attaacttta
    10921 gctggagcta ctttcttagc aataattgct atggtgccag ctcttacaac acattatatg
    10981 aaagtaaata tgagtctagc tgggacttca ttgctaatcg ttgttggagt tgctttggag
    11041 cttaagagac agttagagtc aaacttagtt atgagaagct atcaaggttt cttaaaataa
    11101 aatggagatg gataatatga gaataatatt acttggacct ccaggtgctg gtaaaggtac
    11161 tcaggcggca ggaatagtag aaaaatacaa tatacctcat atatcaacag gagatatatt
    11221 cagaaagaat ataaaagagg gaacagaact tggaaaaaaa gctaaagaat acatggacca
    11281 aggtttatta gtaccagatg agttaactgt aggtttagtt actgatagaa tatctcaaga
    11341 agattgtaaa aatggattta tgttagatgg atttccaaga aatgtagcac aaggagaaca
    11401 tttagatatc ttcttaaaaa atgctggtat atcactagat aaagttgtca atattgaagt
    11461 tgataagagt atattagtgt ctagagcagt tggtagaaga atatgtaagt cttgtggagc
    11521 tacttaccat gttgagttta atcctcctaa agtagaaggt gtatgtgatg tatgccaagg
    11581 agaattatat caaagagctg atgataatga agaaactgta tctaagagaa tacaagttta
    11641 tctagatgaa actaagcctt tagtagatta ttatagcaaa caaggtataa tagcagatat
    11701 aaaaggtgat caagcaatag ataaagtatt tgaagatatt gtcgcagcct taggaagtgg
    11761 aaaataaatg attatcttga aatcaaaaaa agaaatagaa cttttaagag aagcaggtaa
    11821 aatagttgct gacactcatg aagttttaag aaaagctatt tctccgggaa tatctacttt
    11881 agaattagat aaaatagctg aagagaatat aagaaaatac aatgcagaac cttcttttaa
    11941 aggatatgga ggttttccag gaagtatatg tgcttctatc aatagagagg tagtacatgg
    12001 tattccagga gaaactatat tacaagaagg tgacattgta agtttggata taggagccta
    12061 ttataaagga tatcatggtg attctgcgaa aactcacgga gtaggcatga tatctgaaga
    12121 agataggaaa ttgatagaag taactagaga aagcttctat gaaggaataa aatttgctaa
    12181 attaggatat agactttcag atatctcaca cgcagtacaa acacacgttg agaaacatgg
    12241 tttctcggta gttagagatt tagtgggtca tggagttgga gcaaatcttc atgaagaccc
    12301 acaagtacct aattatggac tcccaggaaa aggaccaaga cttagagaag gaatggttat
    12361 tgctatagag ccaatggtta atgcaggtcg ttatcatgta aagactctat cagatgggtg
    12421 gacgactgtt acaatagatg gaaaaaaatc agctcattat gagcatacga tagcaattac
    12481 tgaacatgaa cctttgatat tgacaaagtt gtaatttaaa aagtaggtga aaaaagtgct
    12541 atcagataat ttaagtatag gtcaagttgt taaagtttca ttaggacgag ataaaggaaa
    12601 tttattcttt gtagtcaaaa taattaataa tgaatatgta ttaatagctg atggaaaaaa
    12661 gagaaaactt gacaaaccta agttaaagaa agtgaagcac ttaaaaaaat ataattttat
    12721 taatgatgaa gttagaaaaa gagtagtatc tggacaagag attacagatt cttttttaag
    12781 agctgaactt actaagttaa attagataat ttaacttatt gaaatggagg gctggttagt
    12841 taatggccaa aaaagatgtt atagaattag aaggtacagt ttcagaagct ttacctaatg
    12901 ctatgttcaa agttaaacta gaaaatggac atgagatatt atgccacatt tctggaaagc
    12961 taagaatgaa cttcataaga attcttgaag gtgacaaggt gaatgttgaa ctttctccat
    13021 atgaccttac aagaggaaga attacttggc gtaagaagta gactatatta atatttagtc
    13081 taaggaggga ttaataatga aggttagacc atcagtaaaa ccaatatgtg aaaaatgtaa
    13141 agtaataaaa agaaaaggaa aagtaatggt tatctgtgaa aatccaaagc ataagcaaaa
    13201 gcaaggataa gaaattatta ctagcatttt gttaaatttt atagtataat actatattgt
    13261 gatgttaaca aaagaacgtt aaaatcgttg aacaatctgg cgtaggattg gcatatgatg
    13321 tgaagtttta aacactaaaa actatgtgta ggaggtgcga tcatggcaag aatagctggg
    13381 gtagatttac ctagagaaaa aagagcggag ataggcttaa cttatatata tggtataggt
    13441 aaagcaactg ctaacgaaat attagctaag gctgagataa atccagatac tagaataaaa
    13501 gatttatcag aagatcaagt taatgagtta agaaaagtta tagatgacga tttcttagtt
    13561 gaaggtgact taagaagaga aattgcttta aacataaaga gattaagaga tataaaatgt
    13621 tatagaggaa taagacacgc taaaggtctt ccattaagag gacaaagaac taagactaat
    13681 gctagaacta gaaaaggtcc tagaaaaaca gtatctcgta aaaagaaaaa ataaataaat
    13741 aataactaga tgaaggaggg aaaaggaaaa tggctaaacc aaaaaagaaa gttacacgta
    13801 ttagaagaag agaacgtaaa aatatagaac gtggtcatgc tcatatacaa tcaactttca
    13861 ataatacaat aataacttta actgacgttc acggaaatgc tatatcttgg gcaagttctg
    13921 gacaattagg attcaaagga tcaagaaaat caactccatt tgcatctcaa atggctgctg
    13981 aaacagctgc aaaagctgcg atggaacacg gactaaaaag tgttgaggta ttcgtaaagg
    14041 ggccaggttc aggaagagaa gctgcaataa gagctttaca agcaactgga ctagaagtaa
    14101 ctatgataaa agacgttact ccaatcccac ataacggatg cagaccacca aagagaagaa
    14161 gagtgtaatt aataagagta caataggagg tgtagataaa tggcaagata tacaggtgca
    14221 tcatgtagac aatgccgtag agagggaatg aaattattcc ttaaaggtga tagatgttat
    14281 acagacaaat gtgctatagt aaaaagaaac tatgctccag gtcaacatgg ccaaggaaga
    14341 aagaaagttt ctaactatgg attacaatta agagaaaaac aaaaagttaa aagaatatat
    14401 ggagttttag agactcaatt tagaaattta tatgaacgtg ctgaaaatat gcctggtaaa
    14461 gcaggtgaga acttattaag tttattagag agaagattag ataatgtagt ttacagaatg
    14521 ggactagcat cttctagaaa agaagctaga caattagtga ctcatggtca tttcacttta
    14581 aatggaaata aagtagacat accttcatta atagttaagg ttggagatgt tatagaagtt
    14641 aaagagaaat caagatcttc tgcaaaattc aaaaatttag tagaagttaa ctcaagaata
    14701 gctcctaagt ggttagaagc taatgtagaa ggaatgacag caaaagtagt tggtgttcca
    14761 acaagagaag atatagatct tgagatagca gagcacttaa tcatagaact ttactctaaa
    14821 taataagcac acttttaaaa attattttaa aattttgttt accctcagtg gattactgaa
    14881 ttttaaggag ggttttgtcc atgatagaaa tagaaaagcc aaaagtagat atagttgagc
    14941 ttagcgaaga ctatagatat ggtaagtttg ttatagagcc tctagaaaga ggatatggaa
    15001 taactatagg taacgcatta agaagaatat tattatcatc attaccaggt gtagcagtga
    15061 atgctataaa aatagatgga gttcttcatg aattttcaac aatacctggt gttaaagaag
    15121 atgttactga gataatatta actttaaaag agctttcagc aactatagat ggtgaaggaa
    15181 gtagaacact taaaatagaa gctcaaggac catgctctat cacaggtgca gatataatct
    15241 gtcctccaga tgttgaaata ttaagtaaag atttagcaat agctacatta gatgataatg
    15301 ctaaacttaa tatggagata tttgtagata aaggtagagg ttatgtttct gctgaagaaa
    15361 ataaaacaga gaatgttcca ataggtgttt tacctgtgga ttcaatatat actcctgttg
    15421 agaaggttag ttatcatgtg gaaaacacaa gagttggtca aaaaacagat tatgataaat
    15481 tagtattaga agtttggact aatggtagta taaatcctca agagggaata tcattagctg
    15541 caaaggtatt agttgagcat ttaaacttat ttatagactt aactgaacat gtaagtagtg
    15601 ttgaaatcat ggtagaaaaa gaagaagatc aaaaagaaaa agttcttgaa atgactatag
    15661 aagaattaga tttatcagtt agatcatata actgtttaaa gagagcggga attaatacag
    15721 ttgaagaatt agctaataaa tctgaggatg atatgatgaa ggttagaaac ctaggtaaga
    15781 agtcattaga agaggtaata caaaaactag aagaacttgg attgggatta aaaccaagtg
    15841 aagaatagcg agcaaaggag ggataagaat ggctaagtac cgtaaattag gacgtgaaac
    15901 agctcacaga aaccttatgt taagaaactt agtaacttgc ttactaagaa gtggaagaat
    15961 agaaactaca gtgactagag cgaaagaaac tcgtagaatg gctgaaaaga tgataactct
    16021 tgctaagaga ggagatcttc atgctagaag acaagtttta gcttatgtta tggatgaaac
    16081 agtagttaat aacttattca cagatttagc tccaaaatat gctgagagaa atggtggata
    16141 cactagaata ataaaaatag ggccaagaaa aggcgatgct gctgaaatgg cttttataga
    16201 attagtatag taaggaaagg attaggcttg atggcttaat ctttttttta tttttttgac
    16261 taaggtatga tataataatg tgtaaaatga tttttataag ttattgctta ctaaaaggag
    16321 tatgagttaa tggataatat agtaaaggta aataatattt cgtttgagta tattacagat
    16381 gaagcaaaac ttaaagcaat agataattta agcctagatg ttaaaaaagg agaatttgtt
    16441 gcgataatag gacataatgg ttctggtaag tctactttat ctaaaaactt aaatgctatt
    16501 cttatgccta ctgaaggaaa tattcttatt gatgatatgg atactaaaga agaagaaaga
    16561 ttatgggata taagacaaac tgcaggcatg gtatttcaaa atccagataa tcaaatagtt
    16621 gctactatag tagaagaaga cgttgcattt ggacctgaga acttaggtat agaaccaaaa
    16681 gaaataagac gaattgtaga ggagtcttta aaaagtgtag gtatgtatga tttaagagat
    16741 agacagcctc atttgttatc aggaggtcaa aagcaaagag ttgcaatagc aggaattatt
    16801 gctatgaggc ctaaatgtat aatatttgat gaagcaacag caatgttaga tccatctgga
    16861 agaaaagaag ttatgaaaac aataaaaaga cttaataagg aagaaaatat aactgttata
    16921 catataacgc actttatgga agaagcagta gaagctgata gagttgtagt tatggaaaaa
    16981 ggaaagaaaa tcttagaggg aactcctaga gaagtattca gtaaaataaa gatgttaaag
    17041 gaaatcggtt tagatgtacc ttgtatgaca gagttatcta gtttattaat agaagaaggt
    17101 ataaatatta gtagtgatat attaactgtg gatgagatgg tgatggaatt atgtcaatta
    17161 tagtaaagaa tttaacacat atatataatg aagggatgcc ttttgcaagt aaggcacttg
    17221 atgatgtttc ttttgagatt aaagatagag attttgttgg tcttataggt catacaggct
    17281 caggaaaatc tacattaata caacatttaa atggattact aaagccttcc tcaggagaaa
    17341 tatttataaa tgattttaat ataacagata aaaacttgaa tttaactgag attagaaaaa
    17401 gagtaggggt tgtatttcaa tatccagaat accaattgtt tgaagaaacg attgataaag
    17461 atatagcttt tggaccctct aatttaggct tagaggagtc tgagatacat aacagggtaa
    17521 aagcatcaat ggaagctgta ggacttgatt atgagggatt taaagacaaa tctccttttg
    17581 aattatctgg gggacaaaag cgtagagtag caattgctgg agttatagcc atgaacccag
    17641 aagttctcat attggatgaa ccaactgctg gtcttgaccc tggtggaaga gatgaaattt
    17701 ttaacttaat aaaagactta catgaaaaaa agaatatgac tataatacta tcatcacata
    17761 gtatggatga tatggcaaag ttagcaaaaa ctttaattgt tatgaatcat ggtagcgtag
    17821 aatttatggg aactcctaga gaagtgttta aatcaaatgc tagtaaatta aaagatatag
    17881 gattagatat tccacaagtt ttagaacttg cattgaaatt gagagaaaaa ggctttgaca
    17941 tcagtgagga tatattgact ttagaagaag caaaacagga aatattaaaa gttgtgagag
    18001 gacgaggatt atgttaaaag atataactat agggcaatac tacccaacaa gttctgctat
    18061 tcataaatta gatccaagga taaagcttgt agcgacaatt gtatttatgg tatctatatt
    18121 tgtagtaaat aaattttggc cttatatagt agttttatta tgtttattag ctatgataaa
    18181 attggctaat ataccagtca aatatattgt taagggtgtt aaacctctta aatggattat
    18241 tttgtttaca tttcttataa atattttttt cttaccaggt gatgaaatat ggtcatttgg
    18301 atttttagct attacaaaac agggtctaag acaagcaatt tttatggcaa taagattaat
    18361 atttttagta gttggtacat cattgcttac tttaacaact tcaccaatag aattaactga
    18421 tggaatagag agattgttga atccatttaa gaaaattggt ttgccagttc atgaacttgc
    18481 aatgatgatg acaattgctt tacgttttat tcctacattg ttagatgaga cagacaaaat
    18541 aatgaaggct cagatgtcta gaggtgcaga ttttgaaagt aagaatctta taaatagagc
    18601 aaagaattta gtaccacttt tggtaccttt atttgtaagt gcatttagaa gagctgatga
    18661 attggctatg gccatggagg ccagatgtta cagaggtgga cataatagga ctaagatgag
    18721 agagtctgtt atatcaagaa gggattatat ggcatgtgta tttcaggttg tttatctggg
    18781 agcaattata gctactagat ttatagcaat ttaattaata agttatagat ataatgaggt
    18841 aaagtatgag aaatataaaa attaaaatcc aatacaatgg taagaattat tgtggatggc
    18901 aaaagcaacc tgattcttta gggatacaag gtacaattga aagggctata tatgatataa
    18961 caaaagaaga aaccagtctt atagggtctg gtagaactga ttcaggagtt catgctattg
    19021 gtcagattgc aaattttaaa attaattcag gtataagtat agaaagtata ccaatggcac
    19081 taaatgccaa gttgccaaaa gacatatcag ttatagaagc atgtgaagta aatgatgatt
    19141 ttcactccag atacagtgca aaaggtaaaa catataaata tttagtatat aatagcaagt
    19201 ttagaaatcc aatacttagt gagatatcat atcaagtaaa atatgaactt gattttgata
    19261 aaatgtgttc agaagcaaaa agtttattag gaacacatga ttttaaaggt tttatgagtt
    19321 ctggttcatc tgtaaaagat acagttagaa cgatatatga tattgatata agtaaaaaag
    19381 atgacttgat tacttttgag attagtggta atggtttttt atataacatg gtgaggatta
    19441 ttgttggaac acttgttgat atgggtcgtg gcagaattaa cgaaccattt ttagatataa
    19501 tacaatcaaa aactaggtca agatgtggac atacagctcc agcacaagga ttatttctca
    19561 aaaaagttca ttattaactt gacacaccag gctacatgta ttaaaatata tgagaatgtg
    19621 ttaataagtc cacttgcccc ggacttgaca taaacggtaa aaaaatttta tgaaaagtag
    19681 ttaaggaggg acagttatga aaagttatat agctaagcca gctgatgtac aaagaaaatg
    19741 gtacttagtt gatgctgaag gaaaaacatt aggtcgttta gcaacagaaa ttgcgacagt
    19801 attgagaggt aaacataaac caacatttac tcctcacgtt gatggtggag attttgttgt
    19861 tgtagtaaat gcagaaaaaa tagttttaag tggtaagaaa ttagatcaaa aatattacag
    19921 ataccatact ggttatgtag gtggattaaa agaaatatct tacagagata tgatggataa
    19981 gaaaccagaa gaagttatat cacatgctgt aagcggtatg ttacctaaaa ataaattaag
    20041 aagcagaatg atgactagat taagagtatt tgcaggtgct gagcacactc atgcagctca
    20101 aaatccagaa gttttaaact ttaaataaga ttaataggtg aaaggaggag tttataatgg
    20161 ctaacgttca atattatgga actggaagaa gaaaaagttc tgttgctaga gtaagactag
    20221 ttgcaggtga aggaaatata ttagtaaatg gaagagcatt agaaaattat tttaattatg
    20281 agacattaat aagagatgtt aaacaaccat tagttttaac tggtaatgaa aataaatatg
    20341 atgttatagt aaaagttgaa ggtggaggat tcactggaca agctggagct ataagacatg
    20401 gaatatctag agctttatta aaagctgatt tagatttaag acctgcttta aagaaagaag
    20461 gtttcttaac tagagatgca agaatgaagg aaagaaagaa atacggatta aaagcagcaa
    20521 gaagagctcc acaattctca aaaagataat tacttatttt tttggaaaag caaaatcctt
    20581 tatttactgt tattcagaaa gtattggtat tttaaaaatg ttgggttaag ttaattattg
    20641 atatataata aaataataag atatcttatt aggatgtttt tcattaagaa gaacatcctt
    20701 tttattttga ctatttaata aaaaacatat gctaataaga tttaaatttt atttttataa
    20761 tattgtaatt taaaagttta tataaggtta tat
//
LOCUS       DAMJVG010000067        20746 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.067, whole genome shotgun sequence.
ACCESSION   DAMJVG010000067 DAMJVG010000000
VERSION     DAMJVG010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20746)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20746)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20746
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.067"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            98..1054
                     /locus_tag="PC512_002728"
     CDS             98..1054
                     /locus_tag="PC512_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CorA family divalent cation transporter"
                     /protein_id="HDF2442462.1"
                     /translation="MYILNLNTRETIEDFRDKFYVAENSYLILSAPKNLKLLKETLDI
                     DEITFNDCLKFDEITKLDLFDNYDFLSLNTFELRDGEAVIEEVNMYLSDNFILVVVNE
                     EHFLFEFVKNIILKNSQLEKNPVINLFKINYLILREVIKNGFESLEKVEELILQIEDE
                     MMDNINKNHVSRISDVRGLTRIIVKNTRPLLYIGDRIVKENIRYLKYSNVKKYNLENF
                     QGIDFGIDKLYNFALSTRELADKLLDIYSSRVGEKTNNLITKLTLLTAISAPLTIITG
                     IYGMNFRYMPELNWIYGYPATLFFMLCIIFVGIIIFKIKKLL"
     gene            1231..1386
                     /locus_tag="PC512_002729"
     CDS             1231..1386
                     /locus_tag="PC512_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442463.1"
                     /translation="MKGILKELTAKLYSFFYFMFWGFYFSAGYFFYKNICTSFLVRPY
                     FSDFEHK"
     gene            1516..2529
                     /gene="aroF"
                     /locus_tag="PC512_002730"
     CDS             1516..2529
                     /gene="aroF"
                     /locus_tag="PC512_002730"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003452924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HDF2442464.1"
                     /translation="MIVVLKMGADKNEVKKLIEAIGREGVEVNPIDGTELTVLGLVGD
                     TSKIDAKRIEANKVVEKVMHVVEPFKKANRKFHPEPSIINVNGMEIGSKKIAMIAGPC
                     SVETEDQIVSIAKDVKKSGAGFLRGGAFKPRTSPYAFQGLKYDGLDLLKKAKEKTGLP
                     IVTEIMSTQDIDIFEENVDVIQVGARNMQNFDLLKELGKTNKTILLKRGLSATIEEWL
                     MSAEYIMAGGNENVVLCERGIRTFETYTRNTLDLSAILAVKKLSHLPVIVDPSHAAGK
                     SWMVDSLSKAAIAVGADGLIIEVHNDPAHALCDGKQSIKPNEYDELISELKTIASAVG
                     REI"
     gene            2551..3615
                     /locus_tag="PC512_002731"
     CDS             2551..3615
                     /locus_tag="PC512_002731"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HDF2442465.1"
                     /translation="MEEKLLVNLKENSYNIFIKKNILKNIGEEIKKIYFGNKIFIVTD
                     ENIAKLYLDKVKNNLSESGFEIKSLILKSGEETKSFNTLPKIYDSLLDFKLTRKDLII
                     TLGGGVIGDLGGFAAATFLRGISFIQIPTSLLAQVDSSVGGKVGVDLERGKNLVGSFY
                     QPKAVFIDPNVLLSLPEKFYRDGMAEVIKYGCIKDKTFFNKLLSLKNREEVMQHIEYI
                     IHKCCFIKKTVVEADEKDFGDRMLLNFGHTLGHAIEKYYNFTGYTHGEAVAIGMYKIT
                     LESEKIGITKKGTSELIKSILMNYNLPYEIELRDNKSIVDAISLDKKNLGDTLKIILL
                     KDIGESIIYNTTSKFFQEVR"
     gene            3615..4928
                     /gene="aroA"
                     /locus_tag="PC512_002732"
     CDS             3615..4928
                     /gene="aroA"
                     /locus_tag="PC512_002732"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HDF2442466.1"
                     /translation="MGSLKIYPSKLSGDVKIPPSKSMAHRAVICSSLSNGKSRISNID
                     FSDDIIATIRAMTSLGAIIEKKEDILEISGIFSKEGILNRENQLNQPKLTIDCNESGS
                     TLRFLVPISLAFDGVKRFIGRGNLGKRPLDTYYEIFDRQNIKYSYKENQLDLIISGKL
                     KPDEFRVKGNISSQFITGLLFILPTLESDSKIIITTELESKGYLDLTLSTIKDFGVEI
                     INNNYKEFIIKGNQTYKARDYKVEGDYSQGAFYLSADAIGEDISILDLKEDSLQGDSE
                     VVEILSRMGMEILREGNKIKGITNGLNGTLIDASQCPDIIPVLSVVASLSIGRTTIIN
                     AGRLRIKECDRLHAINVELNKLGANIEEKEDSLIIEGVSKLNGGVEVWSHKDHRIAMT
                     LAIASCRCDKPIILKDFECVSKSYPHFFKDFKMLGGRIDEWNMGK"
     gene            4906..5985
                     /gene="aroC"
                     /locus_tag="PC512_002733"
     CDS             4906..5985
                     /gene="aroC"
                     /locus_tag="PC512_002733"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HDF2442467.1"
                     /translation="MSGIWGNNLKVSIFGESHGNAIGINIDGLPSGIELDLDNIDKEM
                     KRRAPGKNSISTSRNESDIPEILSGYFNGRTTGTPLCAIIRNSDTRSKDYGELKNLMR
                     PGHADFTGNVRYSGFNDYRGGGHFSGRITAPLVFCGAICKQILSQKGIEIGAHIKKIK
                     NIEDMSFDYVNISKQQLSNLQTLELPLLDLSKEEAMKNTIIDAKNQGDSVGGIIECAV
                     VGINVGLGNPFFDSVESTLSHLLFSVPAVKGVEFGLGFELADMYGSQSNDEMYYEGNQ
                     VKSKTNNNGGIIGGITTGMPIIFKVAIKPTPSISRQQNTVNIKDKKDDILYIKGRHDP
                     CIVQRAIPVIEAVTAIGIFDLMKGR"
     gene            5988..7184
                     /gene="pheA"
                     /locus_tag="PC512_002734"
     CDS             5988..7184
                     /gene="pheA"
                     /locus_tag="PC512_002734"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HDF2442468.1"
                     /translation="MEDLTRYRNEIDNIDKELIQLFEKRMNTVLEIARHKMKNNTTIL
                     QKDREEKVLSRAVDNLDNKAYSQETVQFFNSIMEISRGLQKRFIDNDGEQKIEFSLDS
                     SNKNFDLSNVNKYKSLKDELNKKNILVGFPGKSGSFTEEALNKFFNKKISKKQFKEFE
                     DVFIALKNKEINYGIIPIENSSTGAISETYDLLRKYGFYIVGEECIKIDQNLIGIKDT
                     KLEDIKEIYSHPQGIGQCSEFLKQNSTWKLIPFNNTATSAELVRKLQDKTKAAIASKK
                     AASIYGLEIISPCINDIANNYTRFVVISNQIHIEEESNKMSVVFSVEHEAGKLYKVLG
                     YFAKNNINMTKIESRPMKNASWRYFFYIDFECSIYNAKVYDLLELIEHNTAYFKFMGV
                     YKNKTE"
     gene            7231..8040
                     /gene="aroE"
                     /locus_tag="PC512_002735"
     CDS             7231..8040
                     /gene="aroE"
                     /locus_tag="PC512_002735"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HDF2442469.1"
                     /translation="MNFFGLVGEKLSHSVSPQIHKRVFEILNIESAYKNFEISKEDIS
                     KLDGAIKLLGIQGVNVTVPYKERIMKYLDFISPEAKRIGAVNTILLRENMLYGYNTDY
                     FGLDSMFKMANIDVQGKVAVILGTGGASKAALTYFIDSGIEKLYVSTRKKDDKKLLNS
                     KAILIDYEELKHIKGDIILNATPVGMYPNVGISPVSKSIIQNFDILIDLIYNPGETEF
                     LRIGNSMGKKTCDGLYMLVGQAIKSQEIWQDTKIDNSILDVIYNELKLEFL"
     gene            8052..8585
                     /locus_tag="PC512_002736"
     CDS             8052..8585
                     /locus_tag="PC512_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HDF2442470.1"
                     /translation="MINKTKEKLILIGMPGSGKTTIGKLLAKEYNCSFCDMDDYIIQI
                     SQKSIAELFSEGEDIFRNYETQACRELSISDKTVISTGGGVIKKDINMEILKETGIII
                     FIDRPIQKILEDININSRPLLKNGKDRLYNLYNERINLYKKFSDIEILNDKSLNNAVY
                     NITNAVSENFKFDFKEK"
     gene            8606..9445
                     /locus_tag="PC512_002737"
     CDS             8606..9445
                     /locus_tag="PC512_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HDF2442471.1"
                     /translation="MNIVIVGLGVIGGSFAKALKKAGYENVFGVDVDLETLKKAEKAK
                     IIKKGCTTGKELFKKADLIILSIYPRLVVDFLNNNKNFFKKGTIITDTTGIKETLIND
                     VLQIIPDDIDFIFGHPMAGREKKGIDFASEQVFNGANYIITPTGRNNIKNLELVENLI
                     LEIGFKRVKKLTSQKHDEIIAFTSQLPHVMAVALINSDEEGRDTGKFIGDSYRDLTRI
                     ANMNEDLWSELFLGNRDNLLKVIENFESEVNLVKEAIFNNDKNKLIEYFKKSSIRREA
                     LEK"
     gene            9713..11194
                     /locus_tag="PC512_002738"
     CDS             9713..11194
                     /locus_tag="PC512_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HDF2442472.1"
                     /translation="MKKNRLIAKNISIAFIVLFFFSVFTFFYVGNINRVLEYETNDII
                     TVTIAGWIILSFLFLGIIIYILYSKANSQKTIEKVAYTDFVTGYSNWRKFELDVTNLL
                     KKTSQNNKYAMVIFDIDKFKAINDIYGHKKGNLILKDIADTLNELTDINETFARVSAD
                     NFNILLTYNKKEDIINIIKKIMANNELVNLSFGIYEIKDKDLSVSVYSDRASLAKSSI
                     KNNSDVNFAFFNDKLREKLLFEDKIEKEMEYALESGQFVMYLQPKYNIKLDKFCGSEA
                     LVRWQYTEKEVIYPGDFIPIFEKNGFIRKIDMYILEQACKEIRSLFDKGISPLPISVN
                     FSRVDFFKKDFIENIVNICDRYKIPYSLIEIEITESSMFGDTDTLFNVSRNLQDIGFI
                     VAMDDFGSGYSSVNMLKNIPLNVIKLDRGFFVYDKDVDKSQIVIKSIVSLIKQLGIRV
                     VAEGIETRSQIEMLKKANCDIVQGYYFSKPLPIKEFEKLVYKI"
     gene            11227..14664
                     /locus_tag="PC512_002739"
     CDS             11227..14664
                     /locus_tag="PC512_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HDF2442473.1"
                     /translation="MIRAKSLKNVLSIVLIFLFTIISFSDFAFKTNVQEEENSKINLR
                     EISLQSSNAIKIKLDSSLSFIKSVANMVSYFNTIDNSKIVPLLANISKESDFQRISIV
                     SPDGISHTSDGKIINVSKYQYFKKAIKGESNISEVVKSPIDGKDTFVIATPVFNKNNK
                     IIGVLYGSYYNDKLAEFIDITSFNSEGYIDIFESSGQFVLKSSHTNKLIKSSSNIYDI
                     FKKASFDDGYSYKKIYEDTKNNKSGFTSYEYKGENRYATYTPIGVNDWYVISVIPQYT
                     VRRNIDKINQLAFSLIFKVFLLFIMLITYIIYKNNKSQKDILKANKEISSITNSIPGG
                     VQKCTLGETCNINFLSDGFIELFGYTREEIKTLFNNDFYSLIHKDDVERIKKEIFKQL
                     YKNKTVELEYRIITKNGNTVWVLDKGELITEPDGKEYFCCVTVDITRTKQLEQEMEQK
                     NLELEMISENVLGGIIITEFNDDFTIKYANSGYLSMIGYTREQLENELKYKACNLVFY
                     EDRKKALESIQHQLNTKGIAVYQHRIRRRDGNIIWVSIKGRLIVDDDGIEKGIWILND
                     ITDLKNAEQKLKINEERFRIALKQTSNTIFEYDIKTKSLLNTSKELDKYNIYKITKNV
                     PYSLVELGVIHKDFSDDFINMYENVINGAKKASCVVKMKLPDENYIWNKVTLTTIFDE
                     DGNPVRAIGIQEDISKQKEAEIRYNQEGKYHSAILSEAMITYEINVSKDTFIKGNESW
                     QKPFGIKPDNNYSQMVKTIANSIVHKDNKETFLNTFLCENLLDAYKNNVTEIKLEYRR
                     MNQENKMIWVICTMHLIKDSITNDIKALAYVKDIDKQKNEEIRLKLKAERDTLTGLYN
                     KGTTEKLINDFLNSEEASLGMHAFLIVDIDNFKSVNDNLGHVFGDKVLFEVSKNLKPI
                     FRKDDIVGRIGGDEFIVFLKNIQSFENIKKKAEKICDIFRNSYTENKKTYKISGTVGI
                     SFVPEHGTVFEELYKKADIALYYAKSKGKDKYALYNDCIYQNELENNISDNNIKLADK
                     CEKSKPVLKEILDSIDNYIYIVNPNTYELLFVNNKVSRLDLEIKLGETCYKSLLKSDR
                     PCNNCPLNGLEENKHSKFKIETNTFGKNISIASWINCIDGEYNCLIECIDSSLYKNK"
     gene            14682..15428
                     /locus_tag="PC512_002740"
     CDS             14682..15428
                     /locus_tag="PC512_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HDF2442474.1"
                     /translation="MLNSITLILGIIFTIYYFYLKIVFGGISFSEIFLVVGIVLIIYQ
                     IFKKKIKEKKVFYRVLKIIISIFLIVFVVTESLIIFYPKNSLESKSDYLLILGASVKK
                     TTPSTTLKGRLDTALKYLKINDNCYVVVSGGKGSGEKITEAKAMKDYLIKNGIDKNRI
                     IEEDKSTNTYENFKYSKLKIEEHSQRKLSDLKVKIVTTDFHVLRSKILAYRNGYKNTS
                     FYASKSKLSFVPTYYTREFFALWKTIIFDR"
     gene            complement(15377..15685)
                     /locus_tag="PC512_002741"
     CDS             complement(15377..15685)
                     /locus_tag="PC512_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HDF2442475.1"
                     /translation="MNFLKENSTFYFATVEDNKPRVRPFGFIMDYEGKLYFGIEKYKT
                     SYKQLLVNPNIEISTTSKVGKWIRIKGIEKTRYEFISSLFIYYLSKMIVFHNAKNSLV
                     "
     gene            16488..20621
                     /locus_tag="PC512_002742"
     CDS             16488..20621
                     /locus_tag="PC512_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF11 domain-containing protein"
                     /protein_id="HDF2442476.1"
                     /translation="MATVSGQIVFDRNRSATIDSGDSGIANIPVVLQDIATGVRLVVL
                     TDASGNYVFTNVPNGNYRIVEAFGTTGGVPTPGNFATAIVGPVPIAEMPPISPPIGST
                     NLDGTTPNTLLITVAGSDITNQNILNGPVIYTPIENILDSCVSVSNINLITDADNGTF
                     GFFPPGTPSNTGPEIEPYPNVTPDFTYVVPDPTKFTPLDGEYTVQNIMTNAMSNVIGA
                     WWRIADHTTGNETGRMMVVNGFNPGAVFFKSTVQVTPNTNYLFSTWILNLFKVTGYPP
                     PQLGVRIFDQNNNILYQATLGAQIPVNTNAPEWKEVGTVINSQNNNQLTVEFFSEGES
                     AIGNDYAIDDVSLREIAVPTFTPIKTSNTETANVGDIITYTVTLDNTCDSPLTNVFFR
                     DLIPNGLEFIPGTVTVDGVSVPGVDPNTGFSLPDIGGGTGVEVTFDVVVESIPNPNPT
                     NNIANIDYSYTPVEGGIPNDFSVDSNPVPVEVISADIEVTKLSEPTIVNPGEELIYTI
                     KVVNNGPFPSENVVLTDDVPASIINPEYSLDGGVTFQPWTGSLNIGTLEVGETRVIII
                     RGIVNPSTVGIITNTAVVSSTTADPNLNNNTSTIETEVNLLADILVMKTAEPNSAVPG
                     TLLRYTIQVENLGPANAENVILNDDIPASIINPEYSLDGGASFQPWNGSLNIGTLNSG
                     ISLTVLIQGTVSLNSSEYIVNTATVSSTTPDPDLSNNISTIITPVNPQAGISIIKVAD
                     EDVAVPGEEFVYTIEIFNEGPSNATNVVLTDDIPDVILNPEYSLDGGATFQPWNGSLN
                     IGTVAPGQLIRIIIKGLVSSTATGDITNTAEVSADVPEPVTDSSTVTTPIVPSADIEV
                     IKTSNMDTAVPEETFSYTITVTNLGPSAAQSIVLTDDIPDVILNPEYSLDGGVTFQPW
                     NGNLSIGTLDAGEIRSIIIRGTVSQTAVGTIINTATISSPTPDPNPDNNTSTDETDIS
                     PLADISVIKGNEPVAIPGGRFIYGIEIANAGPSFAENVTLTDNIPASILNPEYSIDNG
                     VTFQPWNGSLNIGTLDAGEIRNIIIRGTVSQTAIGTIINTATVSSTTPDPNLNNNTST
                     SEAEVSSSADISVVKRSNQTVVVPGDVLDYTIEVRNAGPSTAQNVTLTDNIPASILSP
                     EYSIDNGVTFQPWNGSLSIGTLDAGEIRNIIIRGIVSQTAIGTIINTATVSSTTPDPN
                     PDNNTSTSEIDISSSADISVIKLANKTEACVGEQIDFVIVVSNAGPENAQNVTLIDNV
                     SDKLKKAVFSLDRGVSFQPWTGSLNIGTLPAGTLRVIILRGIIKSTCLDRLTNIAEVT
                     STTPDSNLNNNISRVQVEIKQFCCNDCGCKDCCCNCCCNDCGCKNCCCNCCKNDFWC"
BASE COUNT         8451 a         2260 c         3447 g         6588 t
ORIGIN      
        1 taaatattaa ataataatta ttaaaatagt gtaaaataat tacagtaagg attataaaaa
       61 atttttagaa tgtaaattga aatttaggag tagatgtatg tatatactga atttaaatac
      121 aagagagact attgaagatt ttagagataa attttatgta gcagaaaatt cttatcttat
      181 attaagtgct ccaaaaaatt taaaattgct taaggaaact ttggatatag atgaaataac
      241 ttttaatgat tgtcttaaat ttgatgaaat aaccaaactt gatttatttg ataattacga
      301 ttttttaagc ctaaatacat ttgaactaag agatggagaa gctgttatag aagaggtaaa
      361 tatgtattta tcagataatt ttatattggt tgtagtgaat gaagaacact ttttatttga
      421 atttgtaaaa aatattattt tgaagaactc tcaacttgaa aaaaatccag ttattaatct
      481 atttaagata aactacttga ttcttagaga agttataaaa aatggttttg agtctttgga
      541 aaaagttgaa gagttaattc ttcaaataga agatgaaatg atggacaaca ttaataagaa
      601 tcatgtatct agaataagtg atgtaagagg attaacaaga attatagtta agaatactag
      661 acctcttttg tatattgggg atagaatagt taaggaaaat ataagatatt taaaatattc
      721 aaatgtaaaa aaatataatt tagaaaattt tcaaggtata gattttggaa ttgacaaatt
      781 atacaatttc gcattgtcaa cacgagagtt agcagataaa ttattagata tttattcttc
      841 cagagtaggt gagaaaacaa ataacttaat tacaaaatta accttgttaa cagccatatc
      901 agcaccactt acaattataa ctggtatata tggaatgaac tttagatata tgccagaatt
      961 aaactggatt tatggatatc cagcaacttt attttttatg ctatgtataa tttttgttgg
     1021 aattataata tttaaaataa aaaaattatt gtaaattaca gatgatgttt aattgatttt
     1081 ataaaaatac atcaattgag aagctgattt aagtaaataa aaaaatattt taaattgaaa
     1141 atatttatag aaaatattga caattatatt ttctttgtta taattattaa acaagaagaa
     1201 taataaatta taaaaatgga ggataatact atgaaaggaa tattaaaaga actaacagca
     1261 aaactttata gcttttttta ctttatgttc tggggctttt attttagcgc tggctatttc
     1321 ttttacaaaa atatatgtac ttcctttctg gtgaggcctt attttagtga ttttgagcat
     1381 aagtaaattt tataaaaatg attattttat atatttatat aagatttagt gcttgataga
     1441 ttattttaga gaactcatta gtgagttctc ttttttattt taaatataaa attataatat
     1501 tgggaggtag taaaaatgat agtagtatta aaaatgggag cagataaaaa tgaagttaaa
     1561 aaattaattg aggctattgg gagagaagga gtagaagtta atcccataga tggaacagaa
     1621 ttaactgttt taggtttagt tggagatact agtaaaatag atgccaaaag aatagaagca
     1681 aataaggtag ttgaaaaagt tatgcatgtg gtagagcctt ttaaaaaggc caatagaaaa
     1741 tttcatccag aaccttcaat cataaatgtt aatggaatgg aaattggttc aaagaaaatt
     1801 gctatgatag ctgggccttg ttctgttgaa acagaagacc aaatagtatc tatagctaaa
     1861 gatgtgaaaa aatcaggtgc aggatttttg agaggtggag cattcaaacc aagaacatca
     1921 ccatacgctt tccaaggatt gaaatatgat ggattggatt tattaaaaaa agcaaaagaa
     1981 aaaacagggc ttcctatagt tacagaaata atgtcaacac aagatataga tatatttgaa
     2041 gaaaatgtag atgtaattca agttggagct agaaacatgc aaaactttga tttattaaaa
     2101 gaattaggta aaacaaataa aacaatactt ttaaaaagag gattatctgc tacaattgaa
     2161 gagtggctaa tgtcagcaga gtatataatg gctggaggaa atgaaaatgt agttctttgt
     2221 gaaagaggta taagaacttt tgaaacatat actagaaata ctttggattt aagtgcaatt
     2281 ttagctgtga agaaacttag tcatttacca gttatagttg acccaagtca tgcagcaggt
     2341 aaatcatgga tggttgactc tttatctaag gcagcaattg cagttggagc agatggtcta
     2401 ataatcgaag ttcataatga cccagcacat gcactttgtg atggaaaaca atcgattaag
     2461 ccaaatgaat atgatgaatt gataagtgaa ttaaagacta tcgcatcagc agttggtaga
     2521 gaaatataat ctataaaagg atggttaaac gtggaagaaa aactattagt aaatttaaaa
     2581 gaaaatagct acaatatatt tattaaaaaa aatatactaa agaatatagg agaagaaata
     2641 aaaaaaatat attttggaaa taagattttt attgtaactg atgaaaatat agcaaaatta
     2701 tacttggata aagtaaaaaa taatttaagt gaatctggat ttgaaattaa atctttaata
     2761 ttaaaatctg gtgaagaaac aaaatcattt aatactcttc ctaaaatata cgatagttta
     2821 cttgacttta agttaactag aaaagatttg attattactt taggaggagg ggtaataggt
     2881 gatttaggtg gatttgcagc agcaactttt ttaagaggta taagttttat tcaaattcca
     2941 acatctttat tagcacaagt tgatagttct gtaggtggaa aagttggagt tgaccttgag
     3001 agaggcaaaa acttagtggg aagcttttac caaccaaagg ctgtgtttat cgacccaaat
     3061 gtattattat cacttccaga aaaattctat agagatggaa tggcagaagt tataaaatat
     3121 ggatgtataa aagacaaaac ttttttcaat aaacttttaa gtttaaaaaa tagagaagaa
     3181 gtaatgcaac atatagaata cattatacat aaatgttgct ttattaaaaa aactgtagtt
     3241 gaagctgatg aaaaagactt tggagataga atgcttctaa actttggcca tacattaggt
     3301 catgctattg agaaatacta caattttacg ggttataccc atggagaagc tgttgccata
     3361 ggaatgtata agataacttt agaaagtgaa aagataggaa ttacaaaaaa agggacatca
     3421 gaacttataa aatcaatttt aatgaattat aatttgcctt atgagattga attaagagat
     3481 aataaatcta tagtagatgc tatatctctt gataaaaaaa atctaggtga tacattaaaa
     3541 ataatacttt taaaagatat tggagagagt attatatata atactacttc taaatttttt
     3601 caggaggtaa gataatggga agtctaaaaa tatatccaag taaattatct ggagatgtaa
     3661 aaataccacc atcaaaaagt atggcacata gggcagttat ttgttcatct ctaagcaatg
     3721 gaaaaagtag aatttctaat atagattttt ctgatgatat aatagctact ataagagcaa
     3781 tgacatcatt aggagctatt atagaaaaga aagaagatat tttagaaatt tcgggaattt
     3841 tttctaaaga aggtatttta aatagagaga atcagttgaa tcaacctaaa ttgacaatag
     3901 attgtaatga atcaggctct acattgagat ttttagtacc tatatcttta gcatttgatg
     3961 gtgtaaaaag gtttataggt agaggaaatc ttggaaaaag accacttgat acttattatg
     4021 agatatttga cagacagaat ataaaatata gttacaaaga aaatcagtta gatttgatta
     4081 tatcaggtaa gcttaaacca gatgaattta gagtaaaagg aaatataagt tctcagttta
     4141 tcacaggttt actgtttata ttgcctacgc tagagagtga ttcaaagata ataattacta
     4201 ctgagctaga atctaaagga tatttagatt taactctttc aacgataaaa gattttgggg
     4261 tagaaattat aaacaataac tataaagaat ttattataaa aggaaatcaa acgtataaag
     4321 cgagagatta taaagtagaa ggagattatt ctcaaggagc attttattta tcagcagatg
     4381 ctataggaga agatattagc atattagacc ttaaagaaga ttctcttcaa ggggatagtg
     4441 aagtagttga aattttatct aggatgggaa tggaaatatt aagagaaggc aacaaaataa
     4501 aaggaataac aaatggttta aatggtactt tgatagatgc atctcaatgc ccagatataa
     4561 tacctgtatt atctgtagta gcatccttaa gtatagggag gactacaata attaatgctg
     4621 gtaggcttag aattaaagaa tgtgatagac ttcatgcaat aaatgttgag ttaaataaac
     4681 ttggagcaaa tatagaggag aaagaggata gtttgataat cgaaggagta agcaagttaa
     4741 atggtggagt agaggtgtgg agtcacaaag accatagaat tgctatgaca cttgcaattg
     4801 cttcttgtag atgtgataaa ccaataatat taaaagattt tgagtgtgta tcaaaatctt
     4861 atccacattt ttttaaagat tttaagatgt taggaggtcg aattgatgag tggaatatgg
     4921 ggaaataatt taaaagtatc aatttttgga gaatctcatg gaaatgctat aggtataaat
     4981 atagatggtc ttccttcggg gattgaactt gaccttgata atattgataa agaaatgaag
     5041 agaagagcac ctggaaaaaa ttctatatct acttcaagaa atgaaagtga tataccagaa
     5101 attctaagtg gatattttaa tggaagaact acaggaacgc cattatgtgc aatcataaga
     5161 aatagtgata ctcgttcaaa agattatgga gagcttaaaa acttaatgag accaggacat
     5221 gcagatttca caggtaatgt gagatattct ggatttaatg actatagagg tggaggtcat
     5281 ttttcaggta ggataacagc tccattagta ttttgtgggg ctatatgtaa acaaatttta
     5341 tcacaaaaag gaatagagat aggagcacac ataaaaaaaa ttaaaaatat agaagatatg
     5401 agttttgatt atgtaaatat ttcaaaacaa cagttatcaa atttgcaaac tttggaacta
     5461 cctttacttg atttatcaaa ggaagaagcc atgaaaaata cgattataga tgcaaaaaat
     5521 caaggagatt cagttggtgg tataattgag tgtgcagtag taggtattaa tgtagggctt
     5581 ggaaatccat tttttgactc tgttgaatct actttatcac atttattgtt ttctgttcct
     5641 gctgtaaaag gtgtagagtt tggtttaggt tttgaacttg cagatatgta tggctctcaa
     5701 agtaatgatg aaatgtatta tgaaggaaat caagttaaga gcaaaacaaa taacaatgga
     5761 ggaattatag gagggattac tactggaatg ccaataattt tcaaagtggc aattaagcca
     5821 actccatcaa ttagcagaca acaaaacaca gttaatataa aagataaaaa ggacgatatt
     5881 ttatatatta aaggcagaca tgacccttgt atagttcaaa gggctatacc tgtaatagaa
     5941 gcagtaacag ccattggaat ttttgatttg atgaaaggac gataataatg gaggatttaa
     6001 cgagatatag aaatgagatt gacaatatag ataaagagct tattcaatta tttgaaaaga
     6061 gaatgaatac agttcttgaa attgccagac ataaaatgaa aaataacact actatacttc
     6121 aaaaagatag agaagaaaaa gtactaagta gagccgtaga taatttagat aataaagcat
     6181 attcacaaga aacggtacag ttttttaatt ctataatgga aattagtaga ggattacaaa
     6241 aaagatttat agataatgat ggtgagcaga aaatcgagtt tagtttagat tcatcaaata
     6301 agaattttga tttgtcaaat gtaaataaat ataagtcttt aaaagatgaa ttaaataaaa
     6361 aaaatatcct agtaggcttt cctggaaaat caggttcatt tacagaagaa gcactaaata
     6421 aattcttcaa caaaaaaata tcaaaaaaac aatttaaaga atttgaagat gttttcatag
     6481 cacttaaaaa taaagaaata aactatggaa taatccccat agaaaattca tctacaggag
     6541 ctatctctga aacttatgac cttttgagaa agtacggttt ttatatagtt ggagaagaat
     6601 gtataaaaat agaccaaaat ttaataggga taaaagacac aaagcttgaa gatataaaag
     6661 aaatatattc tcatccacaa ggtataggac aatgtagtga atttttaaaa caaaatagta
     6721 catggaaatt gatacccttt aataacacag caacaagtgc agaacttgta agaaaacttc
     6781 aagataaaac aaaagcagca attgcaagca aaaaagctgc aagtatttat ggattagaaa
     6841 taataagtcc ttgtataaat gatatagcaa acaactatac aagatttgta gtaatcagta
     6901 atcaaataca cattgaagaa gaatcaaaca aaatgagtgt agtattttct gttgaacatg
     6961 aagcaggaaa actttataaa gtacttggat actttgctaa aaataatata aatatgacaa
     7021 aaatagaatc aagacctatg aaaaatgcct catggagata tttcttttat atagattttg
     7081 agtgttctat atacaatgct aaagtgtacg atttattaga attgatagaa cataatacag
     7141 catattttaa atttatggga gtatataaaa ataaaactga atagataaga taaattttta
     7201 tttaatttat aattattagg aggtgtaagt atgaattttt tcggtctagt aggtgaaaaa
     7261 ctctctcaca gtgtttcacc tcaaatccac aagagagtat tcgagatatt gaatattgaa
     7321 agtgcttata aaaactttga aatttcaaaa gaagatatat ctaagctaga cggtgctata
     7381 aaattattag gaatacaagg ggtaaatgtt actgtaccat ataaggagcg tattatgaaa
     7441 tatcttgatt ttatatcacc agaggcaaaa cgtataggag cagttaatac aattttactc
     7501 agagaaaata tgttatatgg ttacaataca gattactttg gtcttgatag tatgtttaaa
     7561 atggctaata ttgatgttca aggaaaagta gcagttatat taggaactgg aggtgcttct
     7621 aaagctgctc ttacatattt tattgattct ggtatagaaa agctttatgt ttcaactaga
     7681 aaaaaggatg ataaaaaatt attaaatagt aaagctatat taatagatta tgaagaactt
     7741 aaacatataa aaggagatat aatattaaat gctacaccag taggtatgta ccctaatgta
     7801 ggaatttcac cagtgtcaaa atctattata caaaattttg atatattaat agatttaatt
     7861 tacaatcctg gagaaacaga gtttttaaga attggtaata gtatgggtaa aaaaacttgt
     7921 gatggattat atatgctggt ggggcaagca ataaaatctc aggaaatttg gcaagatact
     7981 aaaatagata atagtatttt agatgttata tataatgaac taaaattaga atttttgtaa
     8041 gggagattgt tatgataaat aaaacaaaag aaaaattgat attaataggt atgccaggta
     8101 gtggaaaaac tacaattggt aaacttttgg ccaaagaata taattgtagt ttctgtgata
     8161 tggatgatta tataattcaa atatctcaaa aaagtatagc agagttgttt tcagaaggag
     8221 aagatatctt taggaactat gagactcaag catgtagaga actttctata agtgataaaa
     8281 cagtgatatc tacaggtgga ggtgtaataa aaaaggatat taatatggaa atactaaaag
     8341 aaacaggtat aataattttt attgatagac ctatacaaaa gattttggaa gatataaata
     8401 ttaattcaag accattatta aaaaacggaa aagatagatt gtataatctt tacaatgaga
     8461 gaataaatct ttataaaaaa ttttcagata tagagatttt aaatgataaa tcattaaata
     8521 atgctgtata taatattaca aatgcagtca gtgaaaattt taaatttgac tttaaagaaa
     8581 aataatctag ggggaaataa aaataatgaa tattgttatt gtaggactag gagttatagg
     8641 aggctctttt gctaaagcat taaaaaaagc tggatatgaa aatgtatttg gagtagatgt
     8701 agatttagaa actttaaaaa aagcagaaaa agcaaaaatc ataaaaaaag gatgtactac
     8761 aggtaaagag ttatttaaaa aagctgattt aattatatta tctatatatc ctagattagt
     8821 tgtagatttt ctaaataata ataaaaactt ttttaaaaaa gggactataa ttactgatac
     8881 tacaggaata aaagaaacac ttatcaatga tgtgttgcaa attattccag atgatataga
     8941 ttttatattt ggacatccaa tggcaggtag ggaaaaaaag ggtattgatt ttgcaagtga
     9001 acaagttttt aatggcgcaa attatataat tactccaact ggcagaaaca acataaaaaa
     9061 tttagagtta gttgaaaatt taattttaga gattggattt aaaagagtaa aaaagttaac
     9121 ttcacaaaaa catgatgaga ttatagcttt tacttctcag ttacctcatg ttatggcagt
     9181 tgctcttata aatagtgatg aagaaggtag agatacgggt aaatttattg gagatagtta
     9241 tagagattta actagaattg caaatatgaa tgaagactta tggagtgaac tttttttagg
     9301 aaatagagat aatttactaa aagttataga aaactttgaa tcagaagtaa atttagtaaa
     9361 agaagctata tttaacaatg ataaaaataa attaatagag tattttaaaa aatcatcaat
     9421 aagaagagaa gctttagaaa aataaatatt aatatttaag ctatatatag atgggtataa
     9481 atataagcga tagtgtattt aattgtatta ataaatatgg attcaatata attaaatatg
     9541 ctattgatat atttgtaccc ttaactattg ttatctttta gatgataatg atatttattt
     9601 aaatactctt tattaacaat ttataaaact taattgtaaa aaatacttat taatagtaaa
     9661 ataaagtgaa tcaattatat tataattgct aaagagagtg aggtgtagct atttgaaaaa
     9721 aaatagatta atagcaaaga atatatcaat agcatttata gtactattct tttttagtgt
     9781 atttacattc ttttatgtag gtaatattaa tagagtgtta gaatatgaaa caaatgacat
     9841 aataacagtt acaattgctg gatggattat actttcattt ttatttttag gtattataat
     9901 ttacatatta tattcaaaag caaatagtca aaaaactata gaaaaagtag catatacgga
     9961 ttttgtaaca ggttattcca actggagaaa gtttgaatta gatgttacaa atttattaaa
    10021 gaaaacatca caaaataata aatatgcaat ggtcatattc gatattgata aatttaaagc
    10081 aattaatgat atatatggcc ataaaaaggg aaatttaata ttaaaagata ttgcagatac
    10141 tttaaatgaa ttgactgata tcaatgaaac ttttgctcgt gtaagtgctg ataatttcaa
    10201 tatattatta acatataaca aaaaagagga tataataaat attatcaaaa agattatggc
    10261 aaataatgaa cttgtaaact tatcttttgg aatttatgaa atcaaagata aggatttatc
    10321 tgtaagtgta tatagtgata gagcttcact tgcaaaatca tcaataaaaa ataatagtga
    10381 tgtaaatttt gcatttttta atgacaaatt aagagagaaa ttattatttg aagataagat
    10441 agaaaaagaa atggaatatg ctcttgaaag tgggcaattc gtaatgtatt tacaaccaaa
    10501 atacaatatt aaattagata aattttgtgg aagtgaagcc ctagtcagat ggcaatatac
    10561 agaaaaagag gtcatatatc caggtgattt tattcctata tttgaaaaaa atggatttat
    10621 tagaaagatt gatatgtaca tattagaaca agcttgtaaa gaaatccggt ctttatttga
    10681 taaaggaatt tcacctttac ctatatctgt aaacttctca agagttgatt tttttaaaaa
    10741 agattttatt gaaaacatag taaatatatg tgatagatat aaaataccat atagtttaat
    10801 agaaattgaa attactgaat ctagtatgtt tggagatact gatactctat ttaatgttag
    10861 tagaaaccta caggatattg gctttatagt tgcaatggat gattttggct ctggatattc
    10921 ttctgtaaat atgcttaaaa atataccatt aaatgtaata aaattagata gaggattttt
    10981 tgtttatgat aaagatgttg ataagagtca aattgttata aaaagcatag tttctctcat
    11041 taagcaatta ggaataaggg ttgttgctga aggaattgaa acaagaagtc aaatagaaat
    11101 gttaaaaaaa gcaaattgtg atattgttca aggatattat ttttcaaaac cattaccaat
    11161 taaagaattt gaaaaattag tctataaaat atagtcagcg agtcttaaat gggaggtggt
    11221 gattaagtga taagagcaaa atcgttaaaa aatgtactga gtattgtttt aatattttta
    11281 tttacaataa tttctttttc tgattttgca tttaaaacta atgtccagga agaagaaaat
    11341 agtaaaatta atttaagaga aatatcccta caaagttcca atgctataaa aataaaatta
    11401 gatagttctc tatcctttat taaaagtgtg gcaaatatgg tttcttattt taatactata
    11461 gataactcaa aaatagttcc attattagct aatatatcaa aagaatctga ctttcaaaga
    11521 atctctattg tatctcctga tggaataagt cataccagtg atggcaaaat tatcaatgtg
    11581 tcaaagtatc agtattttaa gaaagctatt aaaggagaaa gtaatatatc tgaagttgtg
    11641 aaatctccaa ttgatggaaa agatactttt gttatagcta ctcctgtatt taataagaat
    11701 aacaaaataa ttggtgtttt atacggttct tactacaatg ataaattagc tgaatttata
    11761 gatataacaa gttttaatag tgaagggtac atagatatat ttgaatctag tggtcaattt
    11821 gttttaaaat cttcacatac aaacaaactg attaagtcaa gtagtaacat atatgatata
    11881 tttaaaaaag cttcttttga tgatggttat agctataaaa aaatatatga agatacaaaa
    11941 aataacaaga gtggctttac ctcatatgaa tacaaaggag aaaatcgtta tgctacttat
    12001 acacccattg gtgtaaatga ctggtatgta atttctgtga taccacaata tactgtaaga
    12061 agaaacattg ataaaataaa tcaattagca ttttctctta ttttcaaggt attcttattg
    12121 tttattatgc ttataacata tattatttat aaaaacaata aatctcagaa agatatacta
    12181 aaagctaaca aagaaatctc atctattaca aatagcattc ctggaggagt acaaaagtgt
    12241 accctgggtg aaacatgcaa tattaatttt ttaagtgatg gatttataga gttgtttggt
    12301 tatacaagag aagaaataaa aacattgttt aataatgatt tttatagttt aatacataaa
    12361 gatgatgttg aaagaataaa aaaagaaatt tttaaacaac tttacaaaaa taaaactgtt
    12421 gaattagaat ataggattat aacaaaaaat ggtaatacag tatgggtttt agataaaggg
    12481 gagcttataa cagaacctga tggaaaagaa tatttttgtt gtgtaactgt agatattact
    12541 agaacaaaac aattagaaca agagatggaa caaaaaaatc tagaacttga aatgatatca
    12601 gaaaatgttt taggtggtat aattataaca gaatttaatg atgattttac tataaaatac
    12661 gctaactctg gttatctttc aatgattgga tatacacgtg aacaattaga aaatgaactt
    12721 aaatacaaag cttgtaatct tgttttttat gaagatagaa agaaggctct tgaaagtata
    12781 caacatcaat taaacacaaa aggaatagct gtatatcaac atagaataag aagaagagat
    12841 ggtaatatta tttgggtttc tataaaagga aggcttattg ttgatgatga tggtattgaa
    12901 aaaggtattt ggattctaaa tgatataaca gatttaaaaa atgcagaaca aaaacttaaa
    12961 ataaatgaag aaagatttag aattgcatta aagcaaacat caaacactat atttgagtat
    13021 gatataaaaa caaagtcact tttaaatact agtaaagagc ttgataaata taatatttat
    13081 aaaattacta aaaatgttcc atattctcta gtagaattag gagttattca taaagatttt
    13141 agtgatgatt ttataaatat gtatgaaaat gtaataaatg gagcaaaaaa agcaagttgt
    13201 gtagttaaga tgaaacttcc agatgaaaat tatatatgga ataaagttac cttgactacg
    13261 atttttgatg aagatggtaa tcctgtaaga gcaattggta tacaggaaga tataagcaaa
    13321 caaaaggaag cagagataag atacaatcaa gaaggtaagt atcattcagc tatattgtcg
    13381 gaagcaatga taacttatga aataaatgta tcaaaggata cttttatcaa aggaaatgaa
    13441 agttggcaaa aaccatttgg aattaagcct gacaataact attctcaaat ggtaaaaact
    13501 atagcaaata gtattgtaca taaagacaat aaagaaacat ttttaaatac atttttatgt
    13561 gaaaacttat tggatgcata taaaaataat gtgactgaaa taaaattaga atatcgaaga
    13621 atgaatcaag aaaataaaat gatttgggtc atttgtacaa tgcacttaat aaaagattct
    13681 attacgaacg atataaaagc acttgcttat gttaaagata ttgacaagca aaaaaatgaa
    13741 gaaattagat taaaattaaa agctgaaaga gatactctta caggattata taataaaggt
    13801 actacagaaa aattgattaa tgatttcttg aactctgagg aagcaagctt aggaatgcat
    13861 gcatttttaa ttgttgatat agataatttt aaatctgtga atgataattt aggacatgta
    13921 tttggagata aagtattatt tgaagtttct aaaaacctaa aacctatatt tagaaaagat
    13981 gatatagtag gtagaattgg tggagatgaa tttatagtat tcttaaaaaa tattcagtct
    14041 tttgagaata tcaaaaagaa agcagaaaaa atatgcgata tatttagaaa ttcttataca
    14101 gaaaataaaa agacatataa aatatctgga acagttggaa tttcatttgt accagaacat
    14161 ggaactgtat ttgaagaact ttataaaaaa gcagacatag cactttatta tgcaaagagc
    14221 aaaggaaaag ataagtatgc actttataat gattgtatct accaaaatga acttgaaaat
    14281 aatataagtg ataataatat aaagttagca gataaatgtg agaaatccaa accagtactt
    14341 aaagaaattc ttgattctat tgataattat atctatatag tgaatccaaa tacttatgaa
    14401 cttctttttg tcaataataa ggtgtctcgt ttggatttag agataaaatt aggagaaacc
    14461 tgttataaat cactattaaa atctgataga ccatgtaata attgccctct taacggatta
    14521 gaagaaaata agcattcaaa attcaaaata gagacaaata catttggtaa aaatatcagt
    14581 atagcaagtt ggattaattg catagatgga gaatacaact gtcttataga gtgtatagat
    14641 tcttctttat acaaaaataa ataaaaaagg actatgaaga tatgttaaat agtataactt
    14701 tgatacttgg tataatattt acaatttact atttttatct caaaatagtt tttggaggaa
    14761 tttcatttag tgagattttc ttagttgtag gaattgtact aattatctat caaatattta
    14821 agaaaaaaat taaagaaaag aaggtttttt atagggtgtt aaaaataata atcagcattt
    14881 ttttaatagt atttgtagtt actgagagtc taattatttt ttatcccaaa aatagtttag
    14941 aatcaaaaag tgattatctc ttaattttag gagcttctgt aaaaaagact acaccaagta
    15001 caaccctgaa gggtaggtta gacactgcat tgaaatacct aaaaattaat gataattgtt
    15061 atgtggtagt atctggtggt aaaggaagtg gagaaaaaat aactgaggca aaagctatga
    15121 aagattatct tataaaaaat ggtatagata aaaataggat aatagaagag gataaatcca
    15181 cgaatactta tgagaatttt aaatattcaa aattgaagat agaagaacat agtcaaagaa
    15241 aactaagcga tttaaaagta aaaatagtaa caacagattt tcatgttctc agaagtaaaa
    15301 tattagcata tagaaatgga tataaaaata cgtcttttta tgctagtaaa tcaaaacttt
    15361 catttgtacc aacttactat acaagagaat tttttgcatt atggaaaaca atcatttttg
    15421 atagataata aataaaaaga ctagatataa actcatatct agtcttttct attcccttaa
    15481 ttctaatcca ttttccaact ttacttgttg tagaaatttc aatattggga tttacaagta
    15541 attgcttata agaagtttta tatttttcga ttccaaaata taattttcct tcataatcca
    15601 ttataaatcc aaatggtctt actcttggtt tattatcttc aactgtagca aaatagaatg
    15661 ttgagttttc ttttaaaaaa ttcattattt tttcatgatt aaatcctctt tgtatcttat
    15721 actaatataa tgaatataaa taaaatattc attatactta atataaatcg atataaaaac
    15781 aattacaata ttatattgat tattcgaaat tatatataaa attcagaaaa aattttagtt
    15841 tacataacaa aaataaagtc aactaaaatt attgatttta gattaaagta ccggattaag
    15901 catttaagta gattttaagc ttgatttgat tggaaaggta caaactatca ccgaaaaaaa
    15961 ttaaacccat ttaaaaagca atataaaagc ttgttatttt tgagaaaaat agactctcta
    16021 aactcaatta gattaaaaat aaaatacaga aaattatatc tctaaatatc ttaaataatt
    16081 aagtttaaat tttacgatat tttgtttgat tatttataat ataaaagcat actcttaatc
    16141 ttcaaaattt aaaaagagta aaaaataaca aaaaaatcac tgacatttca ctgacaaatt
    16201 gtaattttgt tattataaat acattgaaaa tacttgatta ttgaaaaatg gcataaaata
    16261 atacatttta tgccatttac tattatttga tagtttttaa cttatgacat aagatatttt
    16321 ttaacacata caataaaata taaaaaaatt gatattgcaa ataaaaaaaa tacatattag
    16381 atgttataga aaaaaagcgc acttataggc ttaaaatgtc acataaaaga gttttaaaga
    16441 ataatatatt atgaacacaa attttgtaat cacaaaggag tgataatatg gcaacagtat
    16501 caggacaaat agtttttgat agaaatagaa gtgctaccat tgattctgga gactcaggaa
    16561 tagccaatat accagttgta ttacaagata tagcaactgg agttagactt gtggttctca
    16621 cagatgcatc aggaaattat gtttttacta atgttccaaa tggtaactat agaattgtag
    16681 aagcttttgg aactacagga ggagtaccaa caccagggaa ttttgcaaca gcgatagtag
    16741 gtccagttcc aattgcagaa atgccaccta ttagtcctcc tattggttca acaaacttag
    16801 atggtacaac acctaacaca ctattaataa cagtagcagg ttcagatata acaaatcaaa
    16861 atatattaaa tgggcctgtg atttatacac ctatagagaa tatattggat tcttgcgtat
    16921 ctgtatctaa tataaacctt attacagatg cagataacgg aacattcggt ttttttccac
    16981 caggtacacc aagtaataca ggacctgaaa tagaacctta cccaaatgtg acgccagatt
    17041 ttacgtatgt tgtaccagac ccaactaagt ttacaccttt agatggagaa tatacagtac
    17101 aaaatattat gacaaatgca atgagtaatg ttataggagc ttggtggcgt attgctgacc
    17161 atactacagg aaatgaaaca ggaagaatga tggtggtaaa tggttttaat cctggagctg
    17221 tattttttaa atcaacagta caagttacac ctaacactaa ttatttattt agcacttgga
    17281 ttttaaacct ttttaaggta acaggatatc caccaccaca gctaggtgta agaatatttg
    17341 accaaaataa taatatacta tatcaagcaa cattaggagc tcaaattcca gttaatacaa
    17401 acgcaccaga atggaaagaa gtaggtactg tgattaattc tcaaaataat aatcaactta
    17461 cagtagaatt ttttagtgaa ggagaaagcg ccattggaaa tgattatgct atagatgatg
    17521 tttctttaag agaaatagct gttccaactt ttactccaat aaaaacaagt aacacagaaa
    17581 ctgctaatgt aggtgatata atcacatata cagttacatt agataatact tgtgatagcc
    17641 ctttaactaa tgtatttttt agggatttaa ttccaaatgg tttagagttt atacctggaa
    17701 ctgtaacggt tgatggagta tctgtaccag gagtagaccc taatacaggt ttctcacttc
    17761 cagatattgg aggaggaaca ggggttgaag taacttttga tgttgtggtt gaaagtattc
    17821 ctaacccaaa tcctactaat aatatagcta atatagatta ctcctataca cctgtagaag
    17881 gcggtatacc aaatgatttt tcagtagatt ctaatccagt tcctgttgaa gtaatatcag
    17941 cagatattga agttacaaaa ttatctgaac ctactatagt gaatccagga gaggaattaa
    18001 tatacactat aaaagtagta aataatggac cattcccatc tgaaaatgtg gttttaacag
    18061 atgatgtacc agcttctatt ataaatccag agtattcatt agatggagga gtaacttttc
    18121 aaccatggac tggaagttta aatataggga cattagaagt aggagagaca agagttatta
    18181 taattagggg tattgtaaat ccatcaacag taggaattat aacaaataca gctgtagtat
    18241 cttcaactac agcagaccca aaccttaata ataatacatc tacaatagag acagaagtga
    18301 atttattagc agatatttta gtaatgaaaa cagcagaacc taattcagct gttccaggta
    18361 ctttattgag atatactatt caagtagaaa acttaggacc agcaaatgct gaaaatgtaa
    18421 tattaaatga tgatattcca gcttctatta taaatccaga atattcattg gatggaggag
    18481 caagttttca accatggaat ggaagtctta atataggaac tttaaactct ggaatttcat
    18541 taacagtttt aattcaagga acagttagtt taaattcttc agaatatata gtaaatacag
    18601 caacagtttc ttcaactaca cctgacccag atttaagcaa caatatatct accattatta
    18661 caccagttaa cccacaagca ggtatttcta ttataaaagt agctgacgag gatgtagctg
    18721 ttccaggaga agaatttgta tatacaattg aaatttttaa tgaaggacca tctaatgcta
    18781 cgaatgtagt tttaacagat gatataccag atgttatttt aaatccagaa tattcattgg
    18841 atggaggagc aactttccaa ccatggaatg gaagtcttaa tataggtaca gttgcaccag
    18901 ggcaattaat aagaattatc ataaagggat tagtaagttc aactgctaca ggagatatta
    18961 ctaatacagc agaagtaagt gcagatgtac cagaaccagt tacggattca tcaacagtga
    19021 caactcctat agttccatca gcagatatag aagtaataaa aactagcaat atggatacag
    19081 cagttccaga agaaactttc agttatacta taacagttac aaatttagga ccatctgctg
    19141 cacaaagtat cgttttgaca gatgatatac cagatgttat tttaaatcca gagtattcat
    19201 tggatggagg agtaactttc caaccatgga atggaaatct tagtataggc actttggatg
    19261 ctggagaaat aagaagtatt ataataagag gaacagtgag ccagacagca gtaggtacaa
    19321 ttataaatac agcaacaata agttcaccta cacctgaccc aaatccagat aataatactt
    19381 caacagatga aacagatata agtccattag cagatatttc tgtgataaaa ggcaacgaac
    19441 cagttgctat accaggagga agatttattt atggaattga aattgcaaat gcaggaccat
    19501 cttttgcaga gaacgtaact ttaacagata atataccagc ttctatttta aatccagagt
    19561 actcaataga taatggagtg actttccaac catggaatgg aagccttaat ataggtactt
    19621 tagatgctgg agagataaga aatatcataa taaggggaac agtaagtcaa acagcaatag
    19681 gtacaattat aaatacagca acagtaagtt caactacacc tgacccaaat ctaaataaca
    19741 atacttcaac atcagaagca gaggtaagtt catcagcaga tatttctgta gtaaaacgaa
    19801 gcaatcagac tgttgttgta ccaggagatg tactagacta tacaattgag gtgagaaatg
    19861 caggaccgtc tactgctcag aacgtaactt taacagataa tataccagct tctattttaa
    19921 gtccagaata ttcaatagat aatggagtga cttttcaacc atggaatgga agtcttagta
    19981 taggcacttt agatgctgga gagataagaa atatcataat aaggggaata gtaagtcaaa
    20041 cagcaatagg tacaattata aatacagcaa cagtaagttc aactacacct gacccaaatc
    20101 cagataataa tacttcaaca tcagaaatag atataagttc atcagcagat atttctgtaa
    20161 taaaattagc aaataaaaca gaagcatgtg taggagagca aatagatttt gtaatagtag
    20221 tatcaaatgc aggaccagaa aatgctcaaa atgttacttt aatagacaat gtttcagata
    20281 agcttaagaa agcagtattt tcacttgata gaggtgtaag tttccaacca tggactggaa
    20341 gtcttaatat aggtacacta ccagctggaa ctttaagagt gattatatta agaggaatta
    20401 taaaatcaac atgtcttgat agattaacaa atattgcaga agttacttca acaacaccag
    20461 attcaaacct taacaataat atatcaagag tgcaagtaga aataaaacaa ttttgttgta
    20521 atgattgtgg ttgtaaagat tgttgctgta attgttgttg caatgattgt ggttgtaaaa
    20581 attgttgctg taattgttgt aaaaatgact tttggtgttg attttataaa ataattttgt
    20641 ataccttaaa ttaaactgaa ataaaaaata aattcacata tgagtaaaat attttataaa
    20701 tattaataaa ttttctatct ttgatatgga ccacattcgt aatact
//
LOCUS       DAMJVG010000068        20683 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.068, whole genome shotgun sequence.
ACCESSION   DAMJVG010000068 DAMJVG010000000
VERSION     DAMJVG010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20683)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20683)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20683
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.068"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(33..461)
                     /locus_tag="PC512_002743"
     CDS             complement(33..461)
                     /locus_tag="PC512_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442477.1"
                     /translation="MKIHSIQNLTLDTRNLIKKYSLTLNEDLIWEFKHGKYHTIKYFT
                     HKFAVKESVLALLFNIHKLCYAKIKYFESSFSKYEPYKYSYQNEFVKCEMYDMNFMFH
                     KYSNIMIDLRNLQEIKTIEEFRLFCDYLESFEDNLQDLII"
     gene            complement(862..1323)
                     /locus_tag="PC512_002744"
     CDS             complement(862..1323)
                     /locus_tag="PC512_002744"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HDF2442478.1"
                     /translation="MIYEGKLIGKDLKIGIINSRFNEFITSKLLSGAEDCLLRHDVSP
                     ENIEIVWVPGAFEIPLVAQKMAKSGKYDAIICLGCVIRGATSHYDYVCSEVSKGIAKV
                     SLDSELPVIFGIVTTENIEQAIERAGTKAGNKGYDCAMNALEMANLFKSLD"
     gene            complement(1428..2621)
                     /locus_tag="PC512_002745"
     CDS             complement(1428..2621)
                     /locus_tag="PC512_002745"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HDF2442479.1"
                     /translation="MFNTIEEAIEDIKNGKMVIVVDDESRENEGDLLMAAEMATPESI
                     NFMATYGRGLICLPATEKKFKSLNIPLMVRENTDTFQTAFTVTIDGADTLTGISAYER
                     AETVKLFCDENSTSKDFKTPGHIFPLIAKTGGVLVRDGHTEASVDLARLAGFKEIGLI
                     CEIMKDDGTMARVDDLMIFKEKHNLKIITIKDLIEYRKINETTIEKVSSAFLPTKYGN
                     FEIIGYRDTYSNEEHIALTYGNINIENTLVRLHSECLTGDVFHSLKCDCGLQLESSMK
                     KIVENGSGVLIYMKQEGRGIGLLNKIKAYKLQEEGYDTVEANLMLGFEEDMRDFYMAA
                     QILKNLNIKSINLLSNNPDKINQLEKYGIKIENRIPINEEINDFNKLYLKTKKDKMGH
                     LLDII"
     gene            complement(2644..3309)
                     /locus_tag="PC512_002746"
     CDS             complement(2644..3309)
                     /locus_tag="PC512_002746"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HDF2442480.1"
                     /translation="MFTGIVEEVGILRKITANGKSGKVTILSNKILDGTNLGDSIAVN
                     GVCLTVSNLGKNEFTADVMMETIRSTNLGLLNANDKVNLERAMSLSSRFGGHIVTGHV
                     DGKGTICKFEKDENAVLVSIRPDKKLLSSMILKGSVAIDGVSLTISYLDDEIFKVSII
                     PHTKINTILLTKNVGDFVNLESDVIGKYVNNFMANNYKELNSNSSNHKSNIDKDFLFK
                     NGF"
     gene            complement(3343..4455)
                     /gene="ribD"
                     /locus_tag="PC512_002747"
     CDS             complement(3343..4455)
                     /gene="ribD"
                     /locus_tag="PC512_002747"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HDF2442481.1"
                     /translation="MNFVNQKEKDIYYMKKAIELAKNGEGFVNPNPLVGCVIVKDSNI
                     IGKGYHEKFGSNHAEVNAINSAKQSLKDSTLYVNLEPCSHYGKTPPCVDKIIQNKIKR
                     VVISTLDPNPLVCGNGVKKLKDNNIDVTVGILEDEARDLNEAFFYHIKNKRPLCIVKS
                     AVSLDGKIATKSLESKWISNESSRYLTHKYRNKYQSIMVGINTVLNDNPLLTCRLNQE
                     KVSHPTRIVIDTHLKLPLNSNLVKDKTSKTIVFTCCKESIKLSMLKENNVETIISPSK
                     NNLVDLEFVMYKLGELNIDSVLVEGGATLNDSLFRNKLVDKVKLFLSPKIIGGKDAPT
                     FVSGEGINHLSDSTQLTINNVTLIDGDILIESDVLN"
     regulatory      complement(4587..4708)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            4897..7379
                     /gene="recQ"
                     /locus_tag="PC512_002748"
                     /pseudo
     CDS             4897..7379
                     /gene="recQ"
                     /locus_tag="PC512_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729557.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
     regulatory      7468..7579
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            7721..9022
                     /gene="thiC"
                     /locus_tag="PC512_002749"
     CDS             7721..9022
                     /gene="thiC"
                     /locus_tag="PC512_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomethylpyrimidine synthase ThiC"
                     /protein_id="HDF2442482.1"
                     /translation="MNYTTQMDAARKGIITKEMEIVSQKEQVDVNELRELIANGQVVI
                     PANKNHKSLSAEGVGKNLRTKINVNLGISRDCKDIEKELEKVRVAIDMKAEAIMDLSN
                     YGKTREFREKVVEMSPAMIGSVPMYDAVGYLEKELKDITEEEFLNVIRQHAIDGVDFI
                     TIHAGLTRSVCQKIKNHERLTHIVSRGGSLLFAWMELNNKENPIYTNFDKILDICEEY
                     DVTLSLGDACRPGCIKDSTDGVQIQELVVLGELTKRAWERNVQVMIEGPGHMAIDEIE
                     ANVVLEKRLCHGAPFYVLGPLVTDIAPGYDHITSAIGGALACAKGVDFLCYVTPAEHL
                     RLPNLDDMKEGIIAAKIAAHAGDIAKNVKGAREWDNKMSKARADLDWCEMFRLAIDPE
                     KAKRYRDESTPTHEDSCTMCGKMCSMRTVKKILNNEELNLI"
     gene            9076..9270
                     /gene="thiS"
                     /locus_tag="PC512_002750"
     CDS             9076..9270
                     /gene="thiS"
                     /locus_tag="PC512_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur carrier protein ThiS"
                     /protein_id="HDF2442483.1"
                     /translation="MKVNGKEIEFEKDLTVIDLLNKYNLKSDRVVVEVNLEIIEESNY
                     NTYVLKDEDIVELISFIGGG"
     gene            9263..10066
                     /gene="thiF"
                     /locus_tag="PC512_002751"
     CDS             9263..10066
                     /gene="thiF"
                     /locus_tag="PC512_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine biosynthesis protein ThiF"
                     /protein_id="HDF2442484.1"
                     /translation="MVKIKIFVNELLTDVEENTTAYKVRDSYNNKCDVLVLNGYPIKT
                     DMTLCENDKLTLIQKGVKPSLDELESLLIARHTPNIHNKLKKGKVAILGLGGLGSNIA
                     ISLARIGVGELLLIDYDVVEPSNLNRQQYFIDDIGKLKTDAMIENIKKINPFIKLNKR
                     DIFLNKNNMDTIKDSDLIIEAFDDASCKAQVCNYVLINLKDKYLIASSGMAGYYDSNI
                     ITTKKIKDRFYICGDFVNEAKFGEGLMAPRVAICANHMANLATQILIDM"
     gene            10129..10899
                     /locus_tag="PC512_002752"
     CDS             10129..10899
                     /locus_tag="PC512_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiazole synthase"
                     /protein_id="HDF2442485.1"
                     /translation="MDKLVLGGHEFNSRLLVGTGKYGSNNILPEVIKESGSEIITMAL
                     RRVDLDNKQENILTYIPKEMTILPNTSGATNAEEAVRIARISRKMGCGDFIKIEVISD
                     TRYLLPDNEETIKATKILADEGFIVLPYMTPDLYAGRRLIEANAAAVMPLGAPIGSNR
                     GLQMKEMIRIMIDELDIPIIVDAGIGKPSQAMEAMEMGADAVLVNTAIASAGDPVQMA
                     RAFKLAVEGGREAYIAKTGNVSEFANASSPLTGFLGNL"
     gene            10916..12019
                     /gene="thiH"
                     /locus_tag="PC512_002753"
     CDS             10916..12019
                     /gene="thiH"
                     /locus_tag="PC512_002753"
                     /EC_number="4.1.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-iminoacetate synthase ThiH"
                     /protein_id="HDF2442486.1"
                     /translation="MSFYDVIEKYRDFDFDGYLNNVTDNDVLRSLSKDKLEDFDILNL
                     LSKTAVKHLEDMAQKAHKLSVQYFGKTVCLYTPMYIANYCVNQCVYCSYNIKSGIKRK
                     KLTMDEIREEGEAISKEGFKHLLVLTGESSFHSSVEYIGEAIEILREKFPSIGIEVYP
                     MEVEEYKYIVDKGVEGLTVYQETYDEEIYKRVHIKGPKSNYKFRLDAPERGAKAGMRT
                     LSIGALLGLNDFRKETFFTILHGKYLKTKYPHIELSYSTPRMRPFKGCFEELVDISDT
                     DLVQAMVCMRLFDPHAAINISTRENLEMRSHIIPLGVTKLSAGVSTDVGGHSQDEHDT
                     AQFKINDESTVKDVEKMLNSIGYQHVFKDWERF"
     gene            12020..12709
                     /locus_tag="PC512_002754"
     CDS             12020..12709
                     /locus_tag="PC512_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HDF2442487.1"
                     /translation="MYLITNRKLCSEERYLEVIKESILSGVENIIIREKDLEYQELRK
                     LYMKIKTKINCIDFQEQISDESLKTNINQKECRNKFKVNFIINSNIEFFEKVDCQGIH
                     LPFKLFLNLIENKYNFNENKILGLSLHKVEEVDYLEKLIRNQNIKIDYITLSHIYETK
                     CKEGLNPKGIELLKEAKKITDIKIIALGGILPSNVKETLKYCDDFAIMSTIMRSKDIK
                     KTISNYNEKLN"
     gene            12897..14291
                     /gene="yfcC"
                     /locus_tag="PC512_002755"
     CDS             12897..14291
                     /gene="yfcC"
                     /locus_tag="PC512_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HDF2442488.1"
                     /translation="MTDSKKKRFIIPHTFTIIFLLIVLMAILTWIVPSGEFSREDVEG
                     RMVVVPGTYQSVESNPQGFADVFKAPIEGFIDSAEVVGFVLIVGGAFGIVNRTGAIEA
                     GIASVISKFKGKELLIIPISMILFGLGGTTFGMAEETLPFYMIFVPLMTSLGYDSLTA
                     IAIVFIGAAAGAAASTINPFSVGIAQALAQLAPGSGVTYRVVIFIAYILISIAFVMYY
                     AKKVKENPESSIVYEIDKNNKSILNQTSTEIKEFTFKEVSVLAIFGIGMAIMIWGVLS
                     QGWYIPEISMCFAAIGVLSGLVGRLSQIEISESFIDGAKDLASAALAIALARGIVIIA
                     QNGFIIDTILNSAAAFLGGLPKVIFVYLSFFLEAALAFLIPSSSGLASLTVPVLAPLG
                     DLVNISAQVIVTAYQFGVGLTNFITPTSGVLMGALAVAHIPFSKWVRFIMPILLILTA
                     VSLVFLTIGIYIGF"
     gene            14808..16175
                     /locus_tag="PC512_002756"
     CDS             14808..16175
                     /locus_tag="PC512_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HDF2442489.1"
                     /translation="MGLKEFDFIEESIDMLRTMSPTLETISDEIEEYFENILDEKNQE
                     YINVTSRIKSESSLREKIIRNRYLKKYGEASNLIHNVSDLIGLRIECRFIEDENKIYR
                     LLRRYFNKTDDKINYYNKENKNIKLKLSERQPNKQKNGFEIYKIDGVFAYLDREVKFE
                     LQIKSLVNVFWSEIEHKIIYKNNTYLLADKFIKDMMDSIKNNLTMIDNQLLSIYKNFH
                     SGKSFNMKVSKKEIEKLFAKLVYDAFSEKMNKSIGFVVDFKKPCETILNYSFNKQDIS
                     DEVLGNFMLDEFARLNEIVNKDIDFNEQIEFEREPTFDDKFCKDLGNHFRSRLNTEFP
                     WNLFFRILFEIEPYNNTKDFENFVEFIKENVLLEENREQLLCQFEEDSKLIIEDIYDC
                     IFNSISEIDSVEILYNYNLEKINFTSSEIINCICREYECYGEYLEEKEKLMNTFKEKI
                     IQIFE"
     gene            16200..16808
                     /locus_tag="PC512_002757"
     CDS             16200..16808
                     /locus_tag="PC512_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor guanylyltransferase"
                     /protein_id="HDF2442490.1"
                     /translation="MRHFSNIYELSKIILEEAICIEKTGVILAGGRNSRMGRDKAFLE
                     LHDKLFIEIAIEAFKNFDELIIISNNEELYSKYDIKVYNDIVKDVGPIGGIYTALEYA
                     KYDIVTIACDMPYLNNQIVERIANKMNDKSVISVTNGKLQPLCSGYKKSIINKVSLCI
                     RENDLKLRSFIDKIDKSYIYFDEEDLFLNVNTVDEYEKLTKV"
     gene            16856..17227
                     /locus_tag="PC512_002758"
     CDS             16856..17227
                     /locus_tag="PC512_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HDF2442491.1"
                     /translation="MNLLKCDSWAVILNNSDKESKAYKILDELKRNMYKVVAIDEEKK
                     PIEGIDVYECLKDVPHNIDVVAIIDKQSKMDVILEEVELLDIQNMWFEKGSFSEMMIK
                     KTKDLKLNIEYNLSLYDELTR"
     gene            17406..17744
                     /locus_tag="PC512_002759"
     CDS             17406..17744
                     /locus_tag="PC512_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HDF2442492.1"
                     /translation="MLIVTTEKVEGKKISKVLGLVRGSTIRAKHVGKDIGASFKNLVG
                     GELTGYNEMLTEARQIAIGRMVEDAEAKGANAVIAFRLSSASVMQGAAEMLAYGTAVV
                     LEDDNSILEK"
     gene            18210..18713
                     /locus_tag="PC512_002760"
     CDS             18210..18713
                     /locus_tag="PC512_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MogA/MoaB family molybdenum cofactor
                     biosynthesis protein"
                     /protein_id="HDF2442493.1"
                     /translation="MFNVAIITLSDKGYEGKREDITGKKLTEFVENTGAYKVTEYVLI
                     KDDKEMLKENIIRLCNSNKIDLILTNGGTGFSKRDITPEATKEVLEKEIPGLSEYMRM
                     KSTEITKKAILSRGVSGIRNNSIIINLPGSPKGAVENLSFIIDVLDHGIEVLRGEATE
                     CATKKSE"
     gene            18760..19719
                     /gene="moaA"
                     /locus_tag="PC512_002761"
     CDS             18760..19719
                     /gene="moaA"
                     /locus_tag="PC512_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP 3',8-cyclase MoaA"
                     /protein_id="HDF2442494.1"
                     /translation="MIDKYGRKIDYLRISLTDKCNLRCVYCMPPDVKFDKNYINENLS
                     FEDYKFIIKAMAEQGITKIRFTGGEPLLYPKLNELIKFTKEECGINNIGMTTNAIGLS
                     DRIFELEKCGLNKVNISLDSLKEYKYKSVTRGGNLKDVLKSIESCLNLGIKVKLNCVA
                     ISGFNDDELKDFMFLTVKSPIDVRFIELMPLGEANRVYKKGYFNVKEMIEKIYGLYKV
                     KNDEKSTAEYYMFKGAKGRIGIITPLSCSFCNTCNRIRLTSSGAIKLCLHSKEEIDIK
                     PFLHKPLLFRESMKDIIKQKPEKHHLIENKCSDTNRRMYEIGG"
     gene            19723..20193
                     /gene="moaC"
                     /locus_tag="PC512_002762"
     CDS             19723..20193
                     /gene="moaC"
                     /locus_tag="PC512_002762"
                     /EC_number="4.6.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic pyranopterin monophosphate synthase MoaC"
                     /protein_id="HDF2442495.1"
                     /translation="MLTHINEKGYAKMVDISEKDDTKRTAVATATITLSKEALEKVKN
                     GQIKKGDVLSVAQVAGIMGAKNTSSNIPMCHQIKLVGCDLEFDVDDSMSAIKIYATCK
                     SLGKTGVEMEALNACSLAALTIYDMCKAVDKKMVISNIHLVEKTGGKSGDFKFE"
     gene            20229..20660
                     /locus_tag="PC512_002763"
     CDS             20229..20660
                     /locus_tag="PC512_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MOSC domain-containing protein"
                     /protein_id="HDF2442496.1"
                     /translation="MAKVVSINISEKKGVIKVPVQCAELKINHGIVGDAHAGNWHRQI
                     SLLGKESIDKMKMKGFDQLKYGDFAENVTTEGIEVFSLPVGTKLRIGQCEVEVTQIGK
                     KCHNGCEIKKLTGDCVMPREGIFVKVLKEGIINVNDSIDVI"
BASE COUNT         8037 a         2260 c         3488 g         6898 t
ORIGIN      
        1 aattttatct ttaagtttat tctcctaaaa tactatataa ttaaatcctg taaattatct
       61 tcaaagcttt ctaggtaatc acaaaataat ctaaattctt ctatggtttt aatttcttgt
      121 aaatttctca aatctatcat tatattacta tatttatgaa acataaaatt catatcatac
      181 atttcacatt taacaaattc attttgataa ctatatttat aaggttcgta ttttgaaaaa
      241 ctcgactcaa aatattttat tttagcataa cataatttgt gtatgttgaa caaaagtgca
      301 agaacagact ccttaactgc aaacttatgt gtaaagtatt ttatcgtgtg gtatttacca
      361 tgtttaaact cccaaattaa atcctcattt aaagtaagag aatatttttt tataaggtta
      421 cgcgtatcta gtgttaaatt ttgtattgaa tgtattttca taatttattc tcctcataaa
      481 tatttaataa gtattaaatt atagtgtttt attattaatt gttcttaatt atattgtatg
      541 gtaaattaaa aaagtaataa aatagataat taatatacta gtaatatatg ctataaataa
      601 aaacaatagc taaaatagta atatatatgt ttttatgata ttttatgttt agggttatat
      661 ttgtaattat tttaagcttc taaaagtaga tttgatggat aacgtataat tttagaagga
      721 tatgcaattt gtttgataag aacgtacata tgattaaatt aaaaatatta agtaccaaaa
      781 agaagaaaga tagtttctcc ctttggtact taatattttg tatcctttac actaattttt
      841 aatatttatt aatgatatta tttaatctag agacttaaat aaatttgcca tttctagcgc
      901 attcatagca caatcataac ctttatttcc agcttttgta cctgctcttt caatagcttg
      961 ttcaatattt tctgtagtta cgattccaaa tataacaggt aattcactgt ctaaagatac
     1021 tttggctatc cctttagaga cttcactaca tacataatca taatgagaag tagcccctct
     1081 tataacacag cctaaacaga ttatagcatc atacttacca cttttagcca ttttttgagc
     1141 aacaagagga atctcaaaag ctccaggtac ccaaactatt tctatatttt ctggagaaac
     1201 gtcatgtctt aaaagacagt cttcagctcc tgataaaagt tttgatgtta taaattcatt
     1261 aaaacgagaa tttattatac ctatttttaa atcttttcca ataagttttc cttcatatat
     1321 catttttact tcctccaatt ttatttatgt tatagattta tatttataaa tatctttaat
     1381 ttaattataa aaaactactt agtagaaaaa tatcatcata taatcattta tataatatct
     1441 aaaagatgtc ccattttatc ttttttagtt tttaaatata gcttattaaa gtcattaatt
     1501 tcttcattaa tagggattct attttcgatt tttattccat atttctctaa ttgatttatt
     1561 ttatctgggt tattacttaa aagatttata ctttttatgt ttaaattttt taatatttga
     1621 gcagccatat agaaatctct catatcttct tcaaatccaa gcattaaatt tgcttcaaca
     1681 gtatcgtaac cttcttcttg aagtttataa gccttaattt tatttaaaag accaatacct
     1741 ctaccttctt gcttcatata aattaaaact ccacttccat tttccacaat tttcttcata
     1801 gaagattcta gctgtaatcc acaatcacat tttagagagt ggaacacatc tcctgttaaa
     1861 cattcagaat gaagtctaac tagagtattt tctatattta tatttccata agtaagggca
     1921 atgtgttctt catttgaata agtatctcta tatcctatga tttcaaaatt tccatatttt
     1981 gtcggaagga aagcactaga tactttttct atagtagttt catttatttt gcggtattct
     2041 ataaggtctt ttatagtgat gatttttaaa ttatgctttt ctttgaaaat cattaaatca
     2101 tcaactcttg ccattgtacc atcatctttc attatttcac agataagacc aatctcttta
     2161 aaacctgcaa gtctagcaag gtctactgag gcttctgtat gtccatccct gacaagaact
     2221 ccaccagttt ttgctattaa aggaaagatg tgaccaggcg ttttgaaatc tttacttgta
     2281 gaattttcat cacagaataa ttttacagtt tcagctcttt catatgcaga tataccagtt
     2341 agagtatctg ctccatctat agtaacagta aaggctgttt gaaatgtatc tgtattttct
     2401 ctaaccataa gaggtatatt aagactttta aatttttttt cagtggcagg tagacaaatt
     2461 agacctctac catatgtagc cataaaattt attgattcag gagtagccat ttcagctgcc
     2521 atcaataaat ctccttcatt ctctctactt tcatcatcaa ctacgattac cattttccca
     2581 ttttttatat cttcaatagc ttcttcaata gtattaaaca tgtaattcac tcctttatta
     2641 tttttaaaaa ccatttttaa ataaaaaatc tttatctata tttgatttat ggttactact
     2701 attagaattt aattccttgt agttattagc cataaaatta ttaacatact ttccaattac
     2761 atcgctttct aaattaacga aatctccaac attctttgtc aagagaatag tgttaatttt
     2821 agtatgaggt ataatagaaa ccttaaatat ttcatcatct aaatatgata tagttaaact
     2881 tacaccatca atagcaacag aacctttgag tatcattgag gataaaagtt ttttatcagg
     2941 tcgtatactt actaaaactg cattttcatc tttttcaaat ttgcagatag ttcctttacc
     3001 atcaacatga cctgttacta tatgaccacc aaatcttgaa gaaagactca tagctctttc
     3061 aagatttacc ttgtcatttg catttaataa acctaaattt gtggaacgaa ttgtctccat
     3121 cataacatcg gctgtaaatt cattttttcc gaggtttgaa acagttagac aaactccatt
     3181 tacggctata ctatctccaa gatttgtgcc atctaatatt ttatttgata gtatggttac
     3241 ttttccactc ttaccattag cagtaatttt tctaagtatt ccaacttctt ctactatgcc
     3301 agtaaacatc ctaacctcct atatgaatgt attaacaaaa atttaattta aaacatctga
     3361 ttctataaga atatcgccat ctatcaaagt tacattattg attgttaact gtgttgaatc
     3421 tgacaaatga tttattcctt ctccagaaac gaatgtaggt gcatctttac cacctataat
     3481 cttgggtgat agaaataatt tgactttatc aactaactta tttctaaaga gactgtcatt
     3541 gagagtagca ccaccttcaa ctagaacaga atcaatgttt aactctccta atttatacat
     3601 tacaaactcc aaatctacta agttgttttt tgaaggagaa attattgttt caacattatt
     3661 ttcttttaac atagataatt ttatactttc tttgcaacat gtgaaaacta tagttttact
     3721 ggttttatct ttaaccaaat tactattaag tggcaacttt aggtgtgtat ctattactat
     3781 tcttgtagga tgagacactt tttcttgatt gagcctacaa gttagtaaag gattatcgtt
     3841 caaaactgta tttatgccaa ccattatact ttggtattta tttctgtatt tatgagttag
     3901 ataccttgat gattcattag atatccattt tgattctagt gattttgtgg caattttacc
     3961 atctagactt actgctgatt ttacaataca aagaggtctt ttgtttttta tatgataaaa
     4021 aaatgcctca tttaaatctc ttgcttcatc ttctaatatt cccacagtaa catcaatatt
     4081 gttatctttt aattttttta ctccattacc acaaacaagt ggatttgggt ctaatgtaga
     4141 tattacaact ctcttaatct tattttgtat aattttatct acacaaggag gcgttttccc
     4201 ataatgagaa catggttcta agtttacata aagagtagag tcttttagac tttgtttagc
     4261 actgtttata gcatttactt cagcatgatt agagccaaat ttctcatgat atcctttgcc
     4321 tattatatta ctatctttaa caattacaca tccaactaat ggatttggat ttacaaagcc
     4381 ttctccattt ttagccaatt caatagcttt tttcatataa taaatatctt tttctttttg
     4441 attcacaaaa ttcacaatat gtacacctcc tgtttaattg gataattttt aaacaaaaaa
     4501 ccctgagaat taactcaggg tttagaataa tctacaataa atgtttaata aatgtagaac
     4561 aaaattgctc tacaaaaaca ctcattaaat atcttcttcc atccagactt tactgtcggc
     4621 tttggaattt aaccaaatca accaagtttt acattggctc gcgggctata ccgccgattg
     4681 ggaatttcac cctaccccga agattaagta ttaaatttat atttagaatg tatcataaat
     4741 tattttactt tgcaaactat ttttttaaaa aatatatgtt aatatataat atagaatgtc
     4801 tataaacttt gaaataccac gattgtgaat ataaaaataa aaatttgaac ataatcagga
     4861 aagaagtcta attaatttaa attaggagag taatatatga ataaaaaact tttagaaata
     4921 ctatcaaaat actatggata tacaagtttt agaaaaggtc aggaatctat aataaattct
     4981 atcttaagcg aaaaagatgt gctagctatt atgccaacag gagggggaaa atcaatatgt
     5041 tatcaaattc cagctttgat tttagatgga atgacaatag taatttctcc acttatatca
     5101 cttatgaaag accaagtaga tgccttaaag actatgggaa ttagtgctgc ttttataaat
     5161 agttcattaa gtagcaaaga atttaatgaa atattaaata atattagaaa aaataattat
     5221 aaaatactct atattgctcc agagagatta gatgcacaag agtttattga gctaataaat
     5281 aataacaatg taagtcaagt tgcgatagat gaagcacatt gtgtatctca atgggggcat
     5341 gattttaggt tgagttatag aaggatttct gattttataa aaaatttgcc taaaagacct
     5401 atagttacag catttactgc aacagcttca gaagaggtaa gaactgatat aataaattta
     5461 ctgtgtttag aaaatccaga ttattatata actggatttg atagagagaa tttatcaata
     5521 aatatagtaa aatcatctag taaaaataag tatattttag attatattca aaatcataaa
     5581 aatgagtctg gaattatata tgttgcaact agaaaggaag ttgaaaatat atataatggt
     5641 ttatctaaga gaaatatatc tgtatcaaaa tatcatgcag gtttatctaa aaatgaaaga
     5701 agtaaaaatc aagaagattt tataaatgat aatgtggata taatggtagc aacaaatgca
     5761 tttggaatgg gtattgataa acctaatata agatgggtta tacattacaa tatgcctcaa
     5821 agtatagaaa actactatca agaaataggt agagctggta gggatggaga aaaaagtgag
     5881 tgtgtacttt tattttctcc aggagatgta catatacaaa aatatttaat tgatattgga
     5941 gttgaaaatc ctgaaagaaa attatttcag cataagaagc ttcaatacat gattgactta
     6001 gtttacagta attcatgcta tagaaagaca atattgagtt attttggaga aaattatata
     6061 gacaattgca ataattgtag caattgttta gtagagggtg aaatagtaga taaaactata
     6121 gatgcacaaa aagtcatttc atgtgtagct agaatgaaaa gaagttatgg tgttactact
     6181 attgtagatg tgcttagagg ttctaagaat aaaaagattt tacagcttgg attaaatact
     6241 ttgtctacat ataacattat gagagattat tctagtgaag acttaaagaa ttttgtaaat
     6301 acattggttt ctcatggttt tttagattta gttgagactc taggcaatgg aaatagaggt
     6361 agttttccta ctataagatt aaatgagatg tctatgaaag ttttaaaagg tgaagtgaaa
     6421 gtagagttta aagaaattgt tatgacaaaa tcattggaag tagaggatga gttatataat
     6481 gctttaagag aacttagaca ttcaattgca agtgaagaaa ggatagctcc atatatggta
     6541 tttggagatg gtacacttag agccatgtct agtagttatc caattaataa agaagaaatg
     6601 ctagatatct ctggagtagg agaaattaaa taccaaaaat atggtagaga ttttgaagca
     6661 gtaattaaag aatatgtcga aaaaataata taaataaaaa aatagatgaa aaaaatgtcg
     6721 attcaaagaa cgttaatagt gatttcttag aggttaatac agataaagtt ttatatgaaa
     6781 aactgttagt cattagagaa gaatatgcaa caaaggaaaa attacctgca tatatgattt
     6841 tagccaataa ggctttgaaa gaaataagtg gaagatatcc acttgatgaa gaacaattaa
     6901 aagatatttc tggcataggt ggagtaaaat ttgaaaaata tggagctagt attttggcag
     6961 aggttaataa atatgtaaaa gaaaataata ttaatgttat ttgggagaaa aagggcaaaa
     7021 ggaagttaat attagatgga gaaagtagaa aaaataatga aatagcatta gatttgctaa
     7081 atcaaggaaa agatatacaa agtatcagtc aagaaataga agtttcactg tcaaccatta
     7141 ttggatatgt gcatgactat gtaaaggatg gacatagtat atcatttgaa ttaggactag
     7201 aaaattttta taatgaagat aaaaagaaga tgattttaga agtttgcgaa aaagttggct
     7261 atgataattt aaataacata aaaagaaaac ttccagattc aataaagtat gaaaatataa
     7321 gagctgtgat acttgactct tatcttgaaa acttaaaaaa taatattata gcagagtaat
     7381 ttttaactta ataaaaaata aaatttgtat tattgtgttg aactaataat tttgctgtgt
     7441 tatactgaat ttgtaaaaat aatgaaaaat tagagctagg ggcgctagaa ttggctagct
     7501 gagagataaa gccgtaactt acaaacccta ataacctgat caagataatg cttgcgaagg
     7561 gaagcttttt aatataattt tattatataa ataggcaaat tattcaatgt taggagaaat
     7621 ttgtctaagt gtatatacga ttataagagt gctttccaaa cgaggaaaag cacttttttt
     7681 attttcaaaa actataactt taatcttgga ggattgtaat atgaactata caacacaaat
     7741 ggatgctgct agaaaaggca taataactaa agaaatggaa atcgtttctc aaaaagaaca
     7801 ggtagatgta aatgaattaa gagaattaat agcaaatgga caagttgtta taccagctaa
     7861 taaaaatcat aaatctttaa gtgcagaagg tgtaggtaaa aatttaagaa caaaaataaa
     7921 tgtaaatcta ggaatttcaa gagattgtaa ggatatagaa aaagaacttg aaaaagttag
     7981 agtagcaata gacatgaaag ctgaagctat aatggattta agtaattatg gcaaaactag
     8041 agaatttaga gaaaaggttg ttgaaatgtc acctgcaatg ataggttcag tacctatgta
     8101 tgatgcagta ggatatttgg aaaaagaatt aaaagatata acagaagaag agtttttaaa
     8161 tgtaataaga caacatgcta ttgatggagt agactttatt actatacatg caggtcttac
     8221 aagaagtgtt tgccaaaaaa taaaaaatca tgagagattg actcatatag tatctcgtgg
     8281 aggttcttta ttgtttgcat ggatggaatt aaataataag gaaaatccta tttatactaa
     8341 ttttgataaa atattggata tatgtgaaga atatgatgtt acattgagtt taggagatgc
     8401 ttgtagacca ggttgtataa aagattctac tgatggtgtt caaattcaag aacttgtagt
     8461 attaggtgaa cttactaaaa gagcatggga aagaaatgta caagtaatga tagaaggtcc
     8521 tggacacatg gctattgatg aaatagaagc aaatgtagta ttagaaaaga gattatgcca
     8581 tggagcacct ttttatgttc ttggaccatt ggttacagat atagcaccag gttatgacca
     8641 tataacaagt gcaataggag gagctttagc atgtgctaaa ggagtagatt ttttatgtta
     8701 tgtaactcca gcagaacatt taagattgcc taatttagat gatatgaaag agggtataat
     8761 agctgcaaag atagctgctc atgcaggaga tatagctaaa aatgttaaag gtgctcgtga
     8821 atgggataat aagatgagta aagctagagc tgatttagac tggtgtgaga tgtttagact
     8881 tgcaatagac cctgaaaaag ctaagagata cagagatgaa tcaactccta ctcatgagga
     8941 tagttgtact atgtgtggaa aaatgtgctc aatgagaaca gttaagaaaa tattaaacaa
     9001 tgaggaactt aatctaatat aatttttggc tagtatgact ggaataaaaa taagctgaaa
     9061 agaggaggtg atttagtgaa ggttaatggg aaggaaattg aatttgaaaa agatttgact
     9121 gttatagatt tattaaataa atataattta aaaagtgata gagttgtagt tgaagtgaat
     9181 ttagagataa ttgaagaatc taactacaat acatatgtat taaaagacga ggacattgta
     9241 gagcttatta gctttattgg aggtggttaa aataaaaata tttgtaaatg aattattaac
     9301 agatgttgag gaaaatacaa ctgcttataa agttagagat agctataaca ataaatgtga
     9361 tgtattggtg ttaaatggat atccaattaa aacagatatg accctttgtg aaaatgataa
     9421 attaacactt atacaaaaag gagttaagcc atcacttgat gaattggaaa gcttgttgat
     9481 tgctagacat actccaaata tacataataa attaaaaaaa gggaaagttg ctatattggg
     9541 attgggggga cttggttcca atatagctat ctctttagct agaataggag tgggagaact
     9601 tttacttata gattatgatg ttgtagaacc atctaattta aatagacagc agtattttat
     9661 agatgatata ggaaaactaa aaactgatgc catgatagaa aatataaaaa aaataaatcc
     9721 atttataaaa ttaaataaac gagatatttt tttaaacaag aacaatatgg atactattaa
     9781 ggattcagat ttaataattg aggcctttga tgatgcttca tgtaaagcac aggtatgtaa
     9841 ttatgtatta ataaatttaa aagataaata tttaatagca tcatctggta tggcaggtta
     9901 ctatgattca aatataataa ctactaagaa gataaaagac aggttttata tatgtgggga
     9961 ttttgtgaat gaagctaaat ttggtgaagg gcttatggct ccaagggttg ccatctgcgc
    10021 aaatcatatg gcaaatttgg caacgcaaat acttatagat atgtaaatat taaaattaga
    10081 tataaaaaag attgaatatt aaaaaaattt aacgtggagg gaaataatat ggataaattg
    10141 gtacttggtg gacatgaatt taatagcaga ttattggttg gaacaggtaa atatggttca
    10201 aataatatat tgcctgaggt aataaaagaa agtggaagtg aaataataac aatggcactt
    10261 agaagagtgg atttagacaa taaacaagaa aacatattaa cgtatattcc aaaagagatg
    10321 acaatacttc caaatacatc aggagctact aatgcagaag aagctgtaag aatagctaga
    10381 atatctagaa aaatgggatg tggagatttt ataaaaatag aagtaatatc agatactaga
    10441 tatttacttc ctgataatga agaaactata aaagctacaa agatacttgc tgatgagggg
    10501 tttatagttc ttccatatat gacaccagac ctttatgctg gaagaagact tatagaagct
    10561 aatgcagcgg cagttatgcc acttggagct ccaattggtt caaatagagg tcttcaaatg
    10621 aaagaaatga taagaataat gatagatgag ttggatatac caataatagt agatgcaggt
    10681 attggaaaac catctcaagc tatggaggct atggaaatgg gagctgatgc agtacttgtc
    10741 aacactgcta tagcttcagc aggagaccct gtacaaatgg ctagagcatt taaattagct
    10801 gtagaaggtg gaagagaagc atatattgca aaaacaggaa atgtgtcaga atttgcaaat
    10861 gcatcttctc ctttaacagg ttttttaggc aatttataga aagtggtgat tggtgatgag
    10921 tttttatgat gtaatagaaa aatataggga ttttgatttt gatggatatt taaataatgt
    10981 tactgataat gatgttttaa gaagtttatc aaaagacaag cttgaagatt ttgatatatt
    11041 aaatttgctt tctaaaactg cagtaaaaca tttagaagat atggcacaaa aagcacataa
    11101 attaagtgtt caatactttg gtaaaacagt atgtttatat acaccaatgt atatagcaaa
    11161 ttattgtgtt aatcaatgtg tttattgtag ctataatata aagagtggaa taaaaagaaa
    11221 aaaattaact atggatgaaa ttagagaaga gggagaagca atttcaaaag aaggtttcaa
    11281 acatctactt gttttgactg gagaaagtag ttttcactca agtgtagaat atataggtga
    11341 ggctatagaa atattaagag agaaatttcc ctctataggt atagaagttt atccaatgga
    11401 agtagaagaa tataagtaca ttgtagataa aggtgttgaa ggattaacag tatatcaaga
    11461 aacttatgac gaggaaatat ataagagagt acatataaaa ggcccaaaat caaattataa
    11521 atttagacta gatgctcctg aaagaggggc aaaagcaggt atgaggactt tatcaatagg
    11581 tgcactttta gggctaaatg attttagaaa agaaactttt tttacaatat tgcatgggaa
    11641 atacttaaaa acgaaatatc ctcatattga gctttcatat tcaacaccaa gaatgagacc
    11701 ttttaaaggg tgttttgagg aattggtaga tataagtgat actgatttag ttcaagctat
    11761 ggtatgtatg agattatttg accctcatgc agctataaat atatccacta gagaaaattt
    11821 agaaatgaga agtcatataa tacctttagg agtaactaaa ttgagtgcag gtgtatctac
    11881 tgatgtagga ggtcattctc aagatgaaca tgatactgct caatttaaga taaatgatga
    11941 aagtactgtt aaagatgtgg agaaaatgct aaactcaatt ggttatcagc atgtgtttaa
    12001 agattgggaa agattttaaa tgtatctgat aacaaacaga aaattatgta gtgaggaacg
    12061 atatttagaa gttattaaag agtctatatt gagtggtgta gaaaatataa taataagaga
    12121 aaaggattta gaatatcaag agctaagaaa attatatatg aaaataaaaa ctaaaatcaa
    12181 ttgtatagat tttcaagagc aaatatcaga tgaaagtttg aaaactaata taaatcaaaa
    12241 agagtgtaga aataaattca aggttaattt tataataaat agtaacattg aattttttga
    12301 aaaagtggat tgtcaaggta tccatcttcc ttttaaatta ttcttgaatt taattgaaaa
    12361 taagtataat tttaatgaaa ataaaatact aggattatct ttacataaag tagaggaagt
    12421 agattattta gaaaaattaa taagaaatca aaatataaaa atagattaca taacattatc
    12481 acatatatat gaaactaaat gtaaagaagg attaaatcca aaaggaattg agcttttaaa
    12541 agaagctaaa aagattactg atattaaaat aattgcactt gggggaattt taccatctaa
    12601 tgtcaaggaa acattaaaat actgtgatga ttttgctata atgtcaacta taatgaggtc
    12661 taaagatatt aaaaaaacca tatcaaatta taatgaaaag ttgaattagt aaatatagta
    12721 tattgaattt ttaacttaaa taaaaataaa aaagttatct tttaaatttt aaaaggtagc
    12781 ttttttattt tatatctttg ctaataaaaa attgtaaaaa gggaaaactt tagtcagaga
    12841 gattaaacaa tatcctagaa agatttaaaa tttagtaaag tatggaggac attataatga
    12901 ctgacagtaa aaagaaacga tttattatac cacacacttt tacaataata tttttactaa
    12961 tagtcttgat ggcaatattg acttggatag taccaagtgg tgaatttagt agagaagatg
    13021 tagaaggtag aatggtagtt gtaccaggga cttatcaaag tgtagaaagt aatcctcaag
    13081 gatttgcaga tgtttttaaa gcaccaatag aaggctttat cgattcagct gaagttgtag
    13141 gttttgtttt aatagttgga ggtgcttttg gtattgtaaa taggactgga gctatagaag
    13201 caggaatagc ttcggttatc tctaagttta agggaaaaga acttcttata attccaatat
    13261 caatgatttt atttggactt ggaggtacaa catttgggat ggcagaagag acattaccat
    13321 tttatatgat atttgttcca ctcatgacat ccttgggata tgattctcta acagcaatag
    13381 caattgtatt tataggagca gcagcaggag ccgccgcttc aacaataaat ccattttcag
    13441 ttggtattgc acaggcacta gctcaacttg ctcctggttc aggagtaact tacagagtag
    13501 ttatttttat agcatatata ctaataagta tagcatttgt tatgtactat gctaagaagg
    13561 taaaggaaaa tcctgaaagt tcaatagtat atgaaataga taaaaataat aaatcaatac
    13621 ttaatcaaac ttcaacagaa ataaaagaat ttacttttaa agaagtatct gttcttgcta
    13681 tatttggaat agggatggca ataatgattt ggggtgtttt aagtcaagga tggtacattc
    13741 cagaaatatc aatgtgtttt gctgcaatag gtgtgctttc tggattggtt ggtagattat
    13801 ctcaaattga aatctcagaa agttttatag atggagcaaa agatttagca tctgcagctc
    13861 ttgctatagc tttggctcgt ggaatcgtaa taattgctca aaatggattt ataatagata
    13921 ctatattaaa ttccgcagca gcctttctag gtgggcttcc aaaggttata tttgtatatt
    13981 tatcattttt cttggaagct gcattggcat ttttaattcc atcatcttca ggtcttgctt
    14041 cacttacagt acctgtactt gctcctcttg gtgatttggt taatatatcg gctcaagtga
    14101 tagtaaccgc ttatcaattt ggtgtgggtc ttacaaactt tataactcca acttcaggag
    14161 tactgatggg agcacttgca gtagcccata ttccattttc aaaatgggta agatttataa
    14221 tgcctatctt gttgattttg acagctgtat ctctagtctt tttaacaata ggtatttata
    14281 tagggtttta attaagtgta gttttattta agatatttag taatggtata aaatgataat
    14341 atgttttcaa taaattgcca ctaatttaat tagtggtaat ttgttttttg tatttaaaaa
    14401 taaatatatt tacttgtatt ttgaattaat atctacttag acattgtttt aattgttata
    14461 ttttcattta attaagcatt gatttatcat tttttatatt tcatataaca atgcaaaaaa
    14521 taatttttat atagtaaatg acaaaagttt acaataaatg tatattttct tactcattcc
    14581 ttaaaattac tcatttagtt taataactct catttcatat gtaaagttgg taaaaaaatt
    14641 aaaattaaaa gtaaaaaact aaataaatta atgttaattt gaaatatata tgaaggtttt
    14701 tggagaatac ttacttatga taggaaaaaa tgttaaaata atagtgtaat caaatataaa
    14761 ggactgaaat aattaacagt tattaaatat taggagtgta aaaatttatg ggattaaaag
    14821 aatttgattt tattgaagag tctattgata tgttgaggac aatgtcacca acattagaaa
    14881 ctatatcaga tgaaatagaa gagtattttg aaaatatctt ggatgaaaag aatcaagaat
    14941 atataaatgt aacctctaga ataaaatcag aatcaagttt aagagaaaag ataattagaa
    15001 atagatattt aaaaaaatat ggagaagcaa gtaatcttat tcataatgtt tctgacttaa
    15061 taggcctaag aattgagtgt agatttattg aggatgaaaa caaaatatat agacttttga
    15121 gaagatattt taataaaaca gatgacaaaa taaactatta taataaagag aataagaata
    15181 ttaaattaaa actatctgag agacaaccca ataagcaaaa aaatggattt gaaatatata
    15241 aaatagatgg agtttttgcg tatttagata gagaagtaaa atttgaactt caaattaaat
    15301 ctcttgtaaa tgtgttttgg agtgaaatag aacataaaat aatttataaa aacaatacat
    15361 atttacttgc tgataaattt ataaaggata tgatggactc tataaagaat aatcttacta
    15421 tgatagataa tcagctttta agtatttata aaaactttca ttcagggaag tcttttaata
    15481 tgaaagtaag taaaaaagaa attgaaaaat tatttgcgaa actagtctat gacgcttttt
    15541 ctgaaaagat gaataaaagt ataggttttg ttgtagattt taaaaaacca tgtgagacta
    15601 tattgaacta ttcttttaat aaacaagata taagtgatga agttttaggt aattttatgc
    15661 ttgatgagtt tgcaagatta aatgaaattg taaacaagga tatagatttt aatgagcaaa
    15721 tagaatttga aagagaacca acatttgatg ataagttttg taaagaccta ggaaatcatt
    15781 ttagaagtag attaaacaca gaatttccat ggaacctatt ttttagaata ttatttgaaa
    15841 tagagccata taacaatacc aaagactttg aaaactttgt agagtttata aaagaaaatg
    15901 tgctactaga agaaaatagg gagcaattat tatgccaatt tgaagaagat agcaaactta
    15961 taattgaaga tatatatgat tgtatattta atagtataag tgagattgat agtgttgaaa
    16021 ttttatataa ctataatctt gaaaaaataa actttacatc aagtgaaatc ataaattgta
    16081 tatgtagaga atatgagtgt tatggtgaat acttagaaga aaaagaaaag cttatgaata
    16141 catttaaaga aaagattatt caaatctttg agtaataggt caatgctgaa gtggcgctaa
    16201 tgcgccattt ttcaaatata tatgaattaa gtaaaattat tttggaggag gcgatttgta
    16261 tagagaaaac aggtgtaatt ttggcagggg gaagaaattc tagaatgggt agagataaag
    16321 cctttttaga gttacatgat aagcttttta ttgaaattgc aatagaagca tttaaaaact
    16381 ttgatgagtt gataataata tctaataatg aagaattata ttctaaatac gatattaaag
    16441 tttataatga tatagtaaaa gatgttggtc caattggagg aatatatact gctcttgaat
    16501 atgcaaagta tgatatagtt acaattgcat gtgatatgcc atatctaaat aatcaaatag
    16561 tcgaaagaat agctaataaa atgaatgata aaagtgtgat ttcagtgaca aatggaaagt
    16621 tacaaccatt gtgttctgga tataaaaaga gtataataaa taaagtatct ttatgtataa
    16681 gggaaaatga tttaaagctc agaagcttta tagataaaat agataaaagt tatatatact
    16741 ttgatgaaga agatttattt ttaaatgtaa acactgttga tgagtatgaa aaattaacta
    16801 aagtttaatt agctatggtt gtaaaataga gtaggattta tatggaggag agtttatgaa
    16861 tttacttaaa tgcgattctt gggcagtaat attaaataat agcgataaag aaagtaaagc
    16921 atataaaata ttagatgaac ttaaaaggaa tatgtacaaa gttgttgcta tagatgaaga
    16981 gaaaaaacct attgaaggaa tagatgtgta tgaatgttta aaagatgttc cacacaatat
    17041 tgatgttgta gctattattg ataaacaatc taagatggat gtgattttag aagaagtaga
    17101 gcttttggat atacaaaata tgtggtttga aaaaggaagc tttagtgaaa tgatgattaa
    17161 aaagactaaa gatttaaaat taaatataga atataattta agtttatatg atgagttgac
    17221 tagataaaat tatatatctt aataataaaa atataattag ttaataaaac atattatttt
    17281 atagtataga ttggttaata aaagtacaga ttggttaatg aaacattaaa ttacaatatt
    17341 tgttaaaaaa attgtgagtt acatgatata atgtattaaa taggatacta aggagttgat
    17401 atattatgtt aatagtaact acagaaaaag tagaaggtaa aaagatatca aaggttttag
    17461 gattagtgag aggaagtaca ataagagcaa aacatgttgg aaaagatata ggagcaagtt
    17521 ttaagaatct tgttggagga gaacttactg gatataatga aatgctcact gaagcaagac
    17581 aaattgccat aggtagaatg gttgaagatg cagaagctaa aggtgcaaac gcagtaatag
    17641 catttagact gtcttcagct tcagttatgc aaggggcagc agaaatgctt gcttatggaa
    17701 cagcagttgt tttagaagat gataatagta ttcttgaaaa ataaaatata aatagttaaa
    17761 aagaggcatc ttttaaaaat tttatggatg ccttttttta tttgaaaaaa ctaatttgag
    17821 aagaaatttt aactattatg acaataaaat tagggtgata ttatataaat aagtaaaatt
    17881 atattatata atgtatggta tagactttaa aaattttatt tgtagagaaa aatatggaca
    17941 atgttataat aattatagaa attaaaagta cttacattca ttatgtatgt gacatgtata
    18001 attagtttta tatttaatac agttttgaag taatatcttc attttgagaa cgttggaata
    18061 ataaaaaatg tattattata ggtgatataa ataaaaaata aatataatat gttatattgc
    18121 tgatagaaaa gagaataaaa gaaaataggt tttattaaaa gagattttta tttataggac
    18181 ttaatcaatg tatagagggg tgagaacata tgtttaatgt tgcaattata acacttagtg
    18241 ataaaggata tgaaggaaaa agagaagata taacaggaaa aaagttaact gaatttgttg
    18301 aaaatacagg agcttataaa gttactgaat atgtacttat aaaagatgat aaggaaatgc
    18361 taaaggaaaa tattataaga ctttgtaata gtaataaaat agatttaatt cttacaaatg
    18421 gaggtactgg tttttcaaaa agagatataa ccccagaagc aactaaggaa gtgttggaaa
    18481 aagaaatacc aggtctgagc gaatatatga gaatgaaatc cacagaaatt actaaaaagg
    18541 ccatactaag taggggtgta agtggaataa gaaataattc tataataata aatttacctg
    18601 gaagtcctaa aggtgcagtt gaaaatctaa gttttataat tgatgtttta gaccatggca
    18661 tagaagtttt aagaggagaa gctacagaat gtgccactaa aaaaagtgaa tagtatataa
    18721 tctagataga taaaaaatag acaaagaggt agataaagta tgattgataa gtatggaaga
    18781 aaaatagact accttcgtat ttcacttaca gataagtgta atttaaggtg tgtttattgt
    18841 atgccaccag atgtaaaatt tgataaaaat tatataaatg aaaatctaag ctttgaagac
    18901 tacaagttta ttataaaggc tatggctgaa caaggtataa caaaaattag atttactgga
    18961 ggagaacctc ttttatatcc taaattaaat gagcttataa aatttacaaa agaagaatgt
    19021 ggaataaata acataggaat gaccactaat gctattgggc tttctgatag aatctttgag
    19081 cttgaaaaat gtggcttaaa taaagttaat ataagtttag attctttgaa ggaatataag
    19141 tataaatccg taacaagagg aggaaactta aaagatgtct taaaatcgat tgaatcttgt
    19201 ttaaacttag gtataaaagt aaagttaaat tgcgttgcta taagtgggtt taatgatgat
    19261 gagcttaaag attttatgtt tttaacagtt aaatcaccaa ttgatgtaag atttatagag
    19321 cttatgccat taggtgaggc taatagagtt tataagaagg gttattttaa tgtaaaagaa
    19381 atgattgaaa aaatatatgg tttatataaa gtcaaaaatg atgaaaaaag tacagcagaa
    19441 tattatatgt ttaaaggagc taaaggaaga ataggaatta taactccatt aagctgttca
    19501 ttttgtaaca cttgtaatcg tattagactt acttctagtg gtgcaataaa attatgtcta
    19561 cattcaaaag aagaaataga tataaaacca tttttacata aaccattgtt atttagagaa
    19621 tctatgaaag atataataaa acaaaaacca gaaaaacatc atttaataga aaataaatgt
    19681 agtgatacaa ataggcgtat gtatgaaatt ggaggataag taatgttaac acatataaat
    19741 gaaaaagggt atgccaagat ggtggacata agtgaaaaag atgatactaa aagaacggcc
    19801 gtagctacag ctacaattac tcttagtaag gaagcattag aaaaagtaaa aaatggtcag
    19861 ataaaaaaag gagacgtatt gtctgtagct caagttgcag gtataatggg agctaaaaat
    19921 acatcttcaa acataccaat gtgccatcag attaaattag ttggatgtga tttagaattt
    19981 gatgtagatg attctatgtc tgctattaag atatacgcaa cctgtaaatc tcttgggaaa
    20041 actggagtag aaatggaagc tttaaatgca tgttctttag cagcacttac aatttatgat
    20101 atgtgtaaag cagttgataa aaaaatggtt ataagtaata tccatcttgt agagaagact
    20161 ggtggaaaat caggagattt taagttcgag taaattaata atatattggg ttaaaatttg
    20221 gaggaaatat ggcgaaggta gtgtcaataa atataagtga gaaaaaaggt gtaattaaag
    20281 ttcctgtaca atgtgcagag ctaaaaataa atcatgggat agttggagat gcacatgcag
    20341 gaaactggca tcgtcagata agcttacttg gaaaagaaag catagataaa atgaaaatga
    20401 aaggctttga ccaattaaaa tatggagatt ttgctgaaaa tgtaactaca gaagggatag
    20461 aagttttttc cctgcctgtt ggtacaaagt taagaatagg gcaatgtgaa gttgaagtaa
    20521 ctcaaatagg gaaaaaatgt cacaatggat gcgaaattaa gaaattgaca ggtgactgtg
    20581 tgatgccacg agaaggaatt tttgtaaagg ttctaaaaga aggaattata aatgtgaatg
    20641 attcaataga tgtaatctaa tgaagtcact attaaaatat aat
//
LOCUS       DAMJVG010000069        20361 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.069, whole genome shotgun sequence.
ACCESSION   DAMJVG010000069 DAMJVG010000000
VERSION     DAMJVG010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20361)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20361)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20361
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.069"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(194..1081)
                     /locus_tag="PC512_002764"
     CDS             complement(194..1081)
                     /locus_tag="PC512_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF2442497.1"
                     /translation="MAIYLEMPKLIHEFPFRSLSNEGEVLTTPHWHKEIEILLITEGV
                     VNLFINDKPMQLKKGEIVIIKGGDIHYILPSPGSERLVFQFDISFFNDLILLNEEKES
                     LINLFSSIKKCSRDWSAKIRKSVFDILIDIYNEDLYKIEGYSYAIKGKMYNLIPILYR
                     QIPREIEENTVEYEINSKEILERLNNIFKYVEKNYKQPIKLEDVSYEVGFSVYYFTKF
                     FKKNTGKTFITFLNEYRLEKAKWILLNNNISIVDLVEEVGFGSTKTFYRVFKEKIGVS
                     PLEFKKRYNSLEKKGSVSK"
     gene            complement(1181..1630)
                     /locus_tag="PC512_002765"
     CDS             complement(1181..1630)
                     /locus_tag="PC512_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2442498.1"
                     /translation="MEIREILTEESIILDLKSTTKEGIIQELVDKLYDTGSITLKSKF
                     IKALKHREKIGSTSIGYQMAMPHGKTKYVKKASIVIGKSKKGVDWPSIDGLPVKVIIM
                     FAMPQSGGNEDMILISKIAYILGGKNIGERLLNANTKKEILDIFYEV"
     gene            complement(1620..3527)
                     /locus_tag="PC512_002766"
     CDS             complement(1620..3527)
                     /locus_tag="PC512_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF2442499.1"
                     /translation="MLVSRQIEFLKLILNENKYRPIKYFKDKLNVSDKTLQKDLKMIE
                     KYLETFNIKIDIKRGYGILIEDLAKKNIDLINSLNIQSKENKSLSVEQRRMEILKYLL
                     LNSNNITSINQLADKYYVSKTSIVNDFKYIEAWIKEYNLKLNKTLEGTKIIGKEVDIR
                     KSIAKMMDDLLDENYEQHDISELTRLDSATFSALINLFDIDSIIFVETIITELEYNLG
                     YTINQPYYINLITHILICLKRIEEGNQIESQEEREISVDNLDELVYKNVSTLIDKIEN
                     RYRVKITKDEIMYIYIFLVSSGFSSENNSSYNDESDRLSESEKVSSIMIENMSRFLNI
                     NLKNDDLLQKSLASHVRPMLNRLRYDIQIKNPLLGEIQERFSDVLGLCMMTINIMTEY
                     DNLKNISIDEVSYLATYFQAAIERNMSSKRVIVVCHTGYGTSQLLAARLKREFPEWTI
                     VDIVPMHQLSKRNLDDVDFVISTVNLDLKDKLHIVVSVLLMENDINNIKNALLSKPKK
                     SMNLDTNLLGMYLEDNIYFNFDVAQMESLIGVNLGSKYESISLGKDLNIYIHKQSKLN
                     KGIMNINNVTRTIDIYLEISNQSFLKNILMEISNLYRQKNYINYIIDCKSKEDIKILF
                     KNNLLEKTNGN"
     gene            complement(3795..5690)
                     /locus_tag="PC512_002767"
     CDS             complement(3795..5690)
                     /locus_tag="PC512_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2442500.1"
                     /translation="MIGKILRSDCIVLDKQLQTKKDVINYMANHLYHGNYINNKEKFI
                     ADINKREKESSTNMGNLIAIPHAKSNVVNQPVMMYLRTDREITDNDGQKLRSFFMIAV
                     PESGSDEHLKIISKLATYLMEENFLKHLLSAETPYEILSIFNNKAAESGDFSNNQNKG
                     LIVGITGCPTGIAHTFMAKKALEEAGQELGYEVKIETHGAIGVENKLTKEDIKRAEYV
                     IIACDKEVQLSRFIGKKVLQKKVVDAKNVSLAKNLIINAENGMAKEIKPGGKTLEDSK
                     EMLQGSEKKGVYKHLMSGVSEMIPFVVIGGIGIAIAFMFGIFASDPTHETYNPIAGFF
                     GQLGGDSAFKLFIPILAGFIAKSIAGRQGFAPAMIAGFMAVIGGSGFIGGMVAGFATG
                     YIALGVMKITENLPDVLKGVNAVLICPLLIAFTSGAIMFFVVNTPASWLNEALQSWLQ
                     SMSGTNKVLLGAILAGMMASDMGGPINKTASAFGLAMFSSNIFEPSAALMVGGMVPPL
                     AISLAMLIFKNKFTKEERKSSLPTAIMGASFITEGAIPFAAADPLRMIPANIIGSCIG
                     GAICMSLDITLMAPHGGIFVIPFACSAPVAYIACILIGTVITALIIGVTKPTIRSENS
                     EVELLGA"
     gene            complement(5726..6604)
                     /locus_tag="PC512_002768"
     CDS             complement(5726..6604)
                     /locus_tag="PC512_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HDF2442501.1"
                     /translation="MLINMKEMLKVAQENQFAVPAFNIGSGQILKAVVQSANEKNAPV
                     ILAIHPNELSFLGDSFVASCIEEANKSKVPMVIHLDHGENKEQILRAIRCGFTSVMID
                     GSHLPYEENVAISREIVEIAKGLNVSVEGELGTIGTTGTSSEGGTDEIIYTDSKLAKD
                     FVEKTGVETLAIAIGTAHGIYPKGFKPELKLDLLKEIREVVDIPLVLHGGSSNPDEEI
                     AQAVKLGVCKINISSDVKSAYYKKCRELLEQNPSLYEPDTIYPPCIKSAREVIEFKMN
                     LFNAIDKLKCFYKNKN"
     gene            complement(7309..8742)
                     /locus_tag="PC512_002769"
     CDS             complement(7309..8742)
                     /locus_tag="PC512_002769"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003243232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HDF2442502.1"
                     /translation="MKSNQEFLWGGAVAAHQVEGGYNKGGKGISIADVMTAGTHTISR
                     KITDGVIEGLNYPNHEAINFYENYKEDIRLFAEMGYKCFRTSIAWTRIFPKGDESTPN
                     EDGLKFYDDLFDELLKYNIEPVITLSHFEMPYHLVKNYGGWRNRKLIDFFVNFCEVVM
                     NRYKDKVKYWMTFNEINNQSITTNPIYAFTNSGIIYEEQEDKEEVMYQAVHYEFVASA
                     KVVKIGHEINPEFKIGCMVAAMPSYPYSCNPEDMIKFVESNREQLMFTDVHVRGHYPR
                     HTLKLWERKNYNLDITEEDKKILKEGIVDFIGCSYYLTTVVTADKTMKTTGNDSAGKA
                     DVVENPYLKISDWGWNIDPVGLRFYLNQLYDKYELPIFIVENGFGAEDVLKSDNTVDD
                     DYRIEYLASHIREMKNAIEIDGVDVIGYTVWGCIDPVSFTTGEMKKRYGFIYVDKNND
                     GSGTLKRYKKKSFDWYKNVIKFNGEIL"
     gene            complement(8765..10606)
                     /locus_tag="PC512_002770"
     CDS             complement(8765..10606)
                     /locus_tag="PC512_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2442503.1"
                     /translation="MKFERESEEIIKYVGGKENIISLVHCATRLRFKLKDTSKTNKEE
                     LLKMKDVLSVVNSGGQYQVVIGNKVTDYFETIIKKAVLQGQNTEEQGEKVSIVSKIFE
                     SISGAFSPLIPALAGAGMIKALLTILTTMKWMSDTSSTYAILSAAGNAVFYFLPIFLG
                     ITLAIKLSANPYVGGVIGAALLDPNFTALIGAKGGANFFGMPVTAIDYSFGVFPIFVA
                     IFIYYYVDKLLKKIILKDLQLFLVPMISLLVMVPLTVILFGPIATNVGDIISNIFMGL
                     FEFNRVIAGAAIGIAMPFLAVLGLHWGFTPITLQNLATMGGDPIEGAAVAAVFAQIGI
                     AIGLFMKVRKSKKNSELKVLAGSTAVTGILAGVTEPIIYGIILRYRRMIPVLAIAGGI
                     GGGICGVFGVTCNAYVFHNIFSMPVYTPFLGYILGIGTALVLGAVLSYFFGLSKEECE
                     EGNEEVAFDEDDGIEEILSPIEGLQIELSEVEDEVFASGTIGNGMAIIPSKGEVVSPV
                     NGTITTIFPTKHAIGITSDKGVEILIHVGLNTTMLDGKYYTTHMNAGDKVKKGDRIVS
                     FDKDKIEGEGYSIVTPIILTNTNDLADVIVKENKHIKIGTPVIKVVY"
     gene            complement(10732..11565)
                     /locus_tag="PC512_002771"
     CDS             complement(10732..11565)
                     /locus_tag="PC512_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF2442504.1"
                     /translation="MVIKKVFNNNVVFARDNSGQEVILMGKGIGFNKFTKDLVEIDKI
                     EKKFIFNNEESLSELHSLLDRIPLKDVELVSEIIQMGREELGDNLNDSILITLSEHIS
                     YMLKRMDEGLVFQSPLQWEIRQIYPNEYNFSKKAVEYLRKKLDKNIPDSEIAFITIHF
                     ANAQLETKDMQETLLLTKIIDNVLDIIKYHYGIEINEYSFDYTRFISHLRCFIKRQLS
                     GENTNVDTSLLDIIKMKYKSDYNCAKKVKNFLEKTYKWKISENELLYLTLHLNRLSNI
                     K"
     gene            complement(12609..12821)
                     /locus_tag="PC512_002772"
     CDS             complement(12609..12821)
                     /locus_tag="PC512_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2442505.1"
                     /translation="MAILMKTKIKEYREKLLMTQNELAKLVGVRRETIVHLENGKYNP
                     SLKLAMDIAKVFDTTVENLFEFIEEE"
     gene            complement(12822..13238)
                     /locus_tag="PC512_002773"
     CDS             complement(12822..13238)
                     /locus_tag="PC512_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442506.1"
                     /translation="MSKSETGVRSKLILELLVITYFFIAVLATKYIFKGPSTASLPGL
                     SWLIVFGCYSIYNKKYNDLVDESSEFILSKVNKIAIKIMIYSIVIISIFFATPYTSNI
                     NISNLDTGIILIAVLFIQSLSKLVLYIYFDKRGICN"
     gene            complement(13308..13721)
                     /locus_tag="PC512_002774"
     CDS             complement(13308..13721)
                     /locus_tag="PC512_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442507.1"
                     /translation="MSKSELGVKANLVSELMMLSYFFIDLLLQKFIFKGEGIWFTFII
                     LLAFWVCNLMYNKKYNDLVDEASKLMLLKVDQIASKIMLYSMFVIAVLFSVNHTRALD
                     ISNLDIGIMLLAVLFIQSLSKLILYIYFDKKGICN"
     gene            complement(14555..15184)
                     /locus_tag="PC512_002775"
     CDS             complement(14555..15184)
                     /locus_tag="PC512_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HDF2442508.1"
                     /translation="MKNRKVYMYVFDTMSDWEVAYLTAELNTGRYFKKGLKPLKVITV
                     GIDKNPIITMGGLKVLPEITVDEFNMESKDLLILPGGNTWLSMNHEIILEKVKEALIQ
                     DSIVAAICGATLGLAKKGLLDVRNHTSNDLEFLKMVIPNYSGEKYYKTESVVSDENLV
                     TASGIAPLEFTFQVLKLLDVFESEALNSWLNLYKTHDSKYFFELMNCNK"
     gene            complement(15263..16225)
                     /locus_tag="PC512_002776"
     CDS             complement(15263..16225)
                     /locus_tag="PC512_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017561613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HDF2442509.1"
                     /translation="MAKIDNMMSILWMLNSDKKITAKQIAEKLEINIRTVYRYIDVLS
                     ASGVPIISDTGHNGGYSLLNNFTKAPLFFDIEEQKSLLHAALFAKKEGYFLDEALDKS
                     ILKLKMYSNQNQEDILTNHLRALEVIKPIGKVSIESVLKKLENSILKELSVEINYHAG
                     RKAKSKYRIINPYGIVHWNNNWYVVAFCNMRNEVRSFRVDRISEIIETSNTFNRPTEF
                     SASEFFIKGIIPEIKDEQNIIQLVVEGSIDSLDSLSQHWFLGHYLKERTPNKIIFMLE
                     EEVICKYIPNILLPYRKTIQVIEPLSLRKKIIEDLLELIDYYQI"
     gene            complement(16987..>20361)
                     /gene="cbpA"
                     /locus_tag="PC512_002777"
     CDS             complement(16987..>20361)
                     /gene="cbpA"
                     /locus_tag="PC512_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding adhesin CbpA"
                     /protein_id="HDF2442510.1"
                     /translation="EEDSNAGNAEGDANAGNAEEDANAGNAEEDSNAGNAEEDMNALV
                     VEEATAEDPTSVGDFKISGGEINVDFKFASGVLTILSGKQMTIQNNNPNTPTTHRIVI
                     PKDVKAELIFDGVNIKTASNSPFTLTPDKDGGAYAHVILQDGSENKLESGDVYYPGMR
                     AGKGTTLTIDDSVVNRDIEGEFIVPEGGKIPRDVTLENGDKLKKGDRLTLLDSNNRGS
                     LKVVGNYYSAGIGGGNTESGGNIIINGGAITAIGQESSRNTGYGAGIGGGGNGSGGDI
                     TINGGTITAKGAYHGAGIGGGYYTTTKNALSPSVVDPSTGSGYSGNITINGGLSYSYG
                     GAHGSAFGDGCVNPGTNRGYRILVTGGTILPYMTGVGDWIFDLSATTGDVIVTGGSLK
                     ATTFKSLGGAVAYGDLEKKTKVFMNKISLKYLGQDKVSTTLVDDFKMLIDGKIYPYGA
                     PSYTDDQGVLYLWFSDQFKGSEVSVNLVVIDKITGGNIKPDDFYVKDIGSGSQFLKQY
                     EEFTIDDTPPYLIIKRYDGLPFEEDVEKLFLDWILKDGGIPIITPKGEKLTDKKFMTI
                     SSQRLNEETMEPDTNLGSDDLTKQVDAGKYQLSITSTQFSNVYPFNEAYWGHRAYYKA
                     EIIPADTETSLVVEESKAKTDVFKPTDTFTLNVTISPDKKEGPDCASPRGYVQFYING
                     KEYKDPVELKTHNKGSESHNYSTASIEWRPLDSNHHIFTTEQTITVKYIGDDINYIEG
                     SEDEKKLKLDMTNVDVDGDGIPDINIDTDGDGRPDINIDTSGDWKPDINIDTDNTGEW
                     KPSTEGGNGDGIWKPDKNIDTNGDGNPDTDYNRPAIDTDNDGVDDYWKPDKNVDTGSG
                     GYDTGNPNLNKPDPDNGGNSKPDPDNGGNSKPDSGNGGNSKPDSGNGGNSKPDSGNGG
                     NSKPDSGNGGNSKPDPDNGGNSKPDPDNGGNGKPDPDNGGNSKPDPDNGGNSKPDPDN
                     GGNSKPDIDTDGDGKPNINIDIDGDGKPDINIDTDGDGKPDINIDIDGDGKPDINIDI
                     DGDGKPDINIDIDGDGKPDINIDTDGDGKPDINIDTDGNGKPDINIDTDESLDSNVGQ
                     NVQTGDQSNIMLDLALMFISLFFLIKNLTNKYLRRK"
BASE COUNT         6498 a         3658 c         2077 g         8128 t
ORIGIN      
        1 catttttata tcctcattat tgttatctta ttctcatata ttgctgtata tttatatata
       61 aaaggattta tttcgaaata gaggttgtat tgagaactaa aatttagact ttataaatga
      121 atggaatttt cattgttgaa atactgaaaa tatatttgat ttcatataaa agaaagtgcc
      181 tcatgaacta agttcatttt gagacactcc cttttttttc caagctatta tatctttttt
      241 taaattctaa tggagagact ccaatttttt ctttaaatac tctgtaaaaa gtttttgtac
      301 ttccaaaacc aacttcttca accaaatcta caatggatat attgttatta agtaatatcc
      361 actttgcttt ttctaatcta tattcattta aaaaagttat aaatgttttt cctgtatttt
      421 ttttgaaaaa tttagtaaaa taatatacac taaatcctac ttcataagac acatcttcta
      481 attttatagg ttgtttataa tttttttcta catatttgaa tatattgttc aatctctcta
      541 atatctcttt agagtttatt tcatattcta ctgtattttc ttcaatttct ctaggaatct
      601 gtctatataa tataggaatt aaattataca ttttaccttt tattgcataa ctatatcctt
      661 ctattttgta taggtcttca ttgtagatat ctatcaatat atcgaaaact gactttctta
      721 tttttgctga ccaatctcta ctacattttt ttatactact gaataaatta attaagcttt
      781 ctttttcctc atttaataaa attaaatcat taaaaaaaga tatatcaaat tgaaatacta
      841 atctttcact tcccggtgat ggcagtatat aatgaatatc tcctcctttt attatcacta
      901 tctcgccttt ttttaattgc ataggcttgt catttataaa tagatttact acaccttctg
      961 ttataagtaa tatttctatt tccttatgcc agtgtggtgt tgttaatact tctccttcat
     1021 ttgatagact acgaaaagga aattcatgta ttaatttagg catttctaaa tatattgcca
     1081 tatatatcct ctcctctcta gtgtctaaaa attaatttat actatttaaa agaatacaca
     1141 ttttatttta aaaacctcaa atttataatt tatacaatac ctacacttca taaaatatat
     1201 ctaatatttc tttttttgta tttgcattta aaagtctttc acctatattt ttaccaccta
     1261 aaatgtaagc tattttagat attaatatca tatcttcatt gcctccagat tgtggcatag
     1321 caaacataat tattaccttt acaggtaagc catctatact tggccaatct acaccttttt
     1381 tagatttacc tattactatg gatgccttct ttacatattt tgtttttcca tgtggcatgg
     1441 ccatttgata acctatgcta gtagagccta ttttttctct atgttttaat gcctttataa
     1501 acttactttt taaagttata cttcctgtat cgtataattt atctactaat tcctgtatta
     1561 tgccttcttt tgtagttgat ttcaaatcta aaataatgct ttcttctgtt aatatttctc
     1621 taatttccat ttgttttctc caatagatta ttcttaaata atattttaat atcctctttg
     1681 ctcttgcaat ctattatata gtttatatag ttcttttgcc tatataaatt tgatatttcc
     1741 attaaaatat tctttaaaaa actttgatta ctaatttcta aataaatatc aatcgttcta
     1801 gtaacattat tgatattcat tatcccttta tttaatttac tttgcttatg tatatatata
     1861 tttaaatctt ttcctaatga aatagattca tatttactcc ctaaattcac acctattaaa
     1921 ctttccatct gagctacatc aaaattaaaa tatatattat cttctaaata cattcctaat
     1981 aagtttgtat ctaagttcat acttttttta ggtttagaaa gtaaagcatt ttttatatta
     2041 ttaatatcat tttccattaa tagtactgat acaactatat gtaatttatc tttcaaatct
     2101 aagtttacag tagatattac aaagtctaca tcatctaaat ttcgcttact caactgatgc
     2161 ataggaacta tatcaactat agtccattca ggaaattctc tttttaatct ggctgcaagg
     2221 agctgagatg ttccatatcc tgtatgacaa actactatta ctcttttact actcatattt
     2281 ctttctattg ccgcttgaaa atatgtggca agatacgaaa cttcatctat actaatattc
     2341 ttcagattat catactctgt cataatattt atagtcatca tacataatcc cagcacatct
     2401 gaaaatcgct cttgtatctc tcctaacaac gggtttttta tttggatatc atatcttaat
     2461 ctgtttaaca taggccttac atgagatgct agacttttct gtagtaagtc atcatttttg
     2521 agatttatat ttaaaaatcg tgacatattc tctatcatta tagatgaaac tttttcactt
     2581 tcacttaatc tatctgattc atcattgtaa ctactattat tttcgctact aaatccagat
     2641 gataccaaaa aaatatatat gtacataatt tcatctttcg ttatttttac tctgtatcta
     2701 ttttctattt tatctataag tgtactgaca tttttatata ctaactcgtc caaattatct
     2761 acagaaattt ctctttcttc ctgagattct atttgattac cttcttcgat tctctttaaa
     2821 catataagta tatgggtaat taaatttata tagtagggct gatttatagt atatcctaaa
     2881 ttgtattcta attctgtaat tatagtttct acaaatataa tagaatcaat atcaaataaa
     2941 tttatcaatg cactaaatgt agcagaatct aatcttgtta actcagatat atcatgttgt
     3001 tcataatttt catctaataa atcatccatc attttggcaa tcgatttcct tatatccact
     3061 tctttaccta taatcttagt tccttctaaa gttttattaa gttttaaatt gtattctttt
     3121 atccatgcct ctatatattt aaaatcattt actatagaag ttttacttac ataatattta
     3181 tctgctaact gatttattga agttatatta tttgaattta gtaataaata ctttaaaatc
     3241 tccattcttc tctgctctac tgataaagat ttattttcct tcgattgtat atttaaacta
     3301 ttaattaagt ctatattctt ctttgctaaa tcttctatta atattccata gcctcttttt
     3361 atatcaattt ttatattaaa agtttctaaa tatttctcaa tcatcttcaa atctttttgt
     3421 aaagttttat cagatacatt taatttatct ttaaagtatt ttataggtct atatttattt
     3481 tcgtttagta tcaatttaag aaattcaatt tgcctcgaca caagcatact tagccctccc
     3541 tacctatgtt tatatatttc tatgtttata ttaagtacta ttttaacata tttactaact
     3601 atgtaaaatt actaagatac ttctgtatca taaaagaatt tatgatacac cttactaaat
     3661 tgatataata gataatataa tttcaaaata aaaattaagg atatttagaa gtagttaact
     3721 gattctaaat atccttatta ttattctata tacttgttgt tattccatta attattttta
     3781 ctattattta taatttaagc accaagtaat tcaacttcac tattttcact ccttatagta
     3841 ggctttgtta cccctataat caatgctgtt attactgtac caatcaatat acaagctata
     3901 tatgcaactg gtgcactaca tgcaaatggt attacaaata ttcccccatg tggtgccatt
     3961 aaagttatat ctaaactcat acatattgcc ccacctatac aagaaccaat tatatttgct
     4021 ggaatcattc ttaatgggtc tgcagctgca aacggtattg cgccttctgt tatgaaagat
     4081 gcccccatta tagcagttgg tagagatgac tttctttctt ctttagtaaa cttatttttg
     4141 aatattaaca tagctaatga tattgctaat ggaggtacca ttcctcctac cattaatgct
     4201 gctgatggtt caaatatatt acttgaaaac atagccaatc caaaagctga agctgtttta
     4261 ttaataggtc ctcccatatc tgatgccatc atccctgcta atattgcacc taataatact
     4321 ttattagttc cagacatact ttgtaaccaa gattgtaaag cttcatttaa ccatgatgct
     4381 ggcgtattaa ctacaaagaa cattatagct ccactcgtaa atgcaatcaa aagtggacat
     4441 atcaatacag catttactcc ttttaataca tctggtaaat tttctgttat cttcattact
     4501 cctaaagcta tatatcctgt tgcaaaacca gctaccatac cacctataaa acctgaacct
     4561 ccaataactg ccataaaacc agctatcata gcaggagcaa atccttgtct tcctgctatt
     4621 gatttagcta taaaaccagc aagtatcggt ataaataact taaatgctga atcgcctcca
     4681 agttgtccaa agaatccagc tatagggttg tatgtttcat gagttgggtc tgatgcaaat
     4741 ataccaaaca taaaagctat ggctatacca attccaccta tcactacaaa tggaatcatt
     4801 tcagatacac cactcattaa gtgcttataa acaccctttt tctctgaccc ttgaagcatt
     4861 tcttttgaat cttctaaagt ctttccacct ggtttaattt ctttagccat tccattttca
     4921 gcgtttataa ttaaattttt agctaatgaa acattcttag catctactac tttcttttgt
     4981 agcactttct ttcctataaa tctactcagt tgaacttctt tatcacaagc tattattacg
     5041 tattcagctc tttttatatc ttctttagtc aacttatttt ctacacctat agctccatga
     5101 gtttctattt taacttcata tccaagttct tgacctgctt cctctaatgc tttttttgcc
     5161 ataaaagtat gagctatacc tgttggacat cctgttatcc caactataag acctttattt
     5221 tgattattac taaaatctcc tgattctgca gctttattat taaatatact taatatttcg
     5281 tatggagttt ctgcacttag tagatgctta agaaaatttt cttccattag atatgtagct
     5341 agtttagata taatcttaag atgttcatct gaacctgatt ctggaactgc tatcataaaa
     5401 aatgacctaa gtttttgacc atcattatct gtaatctctc tatctgttct taaatacatc
     5461 attacaggtt gatttactac atttgactta gcatgaggta tagctattaa attacccata
     5521 ttagttgatg attctttttc gcgtttatta atatcagcta taaacttttc tttattattt
     5581 atataatttc catggtacaa atgatttgcc atataattaa ttacatcttt ttttgtttgt
     5641 aattgtttat ctagtacaat acaatcgctt cgtagtattt tacctatcat aaattctccc
     5701 ctccttttaa tttgttacct cataattaat ttttattttt ataaaagcac tttaacttat
     5761 ctatagcatt gaatagattc attttaaact ctataacttc tcttgcagat tttatacatg
     5821 gtggatatat agtatctggc tcatataagc ttgggttttg ttctaatagt tctctgcact
     5881 tcttataata tgccgactta acatcactcg aaatatttat tttacaaact cctagtttaa
     5941 ctgcttgtgc tatttcttca tctggatttg atgaaccacc atgaagaact aaaggtatat
     6001 ctactacttc tcttatttct tttaataaat ctagtttaag ctctggttta aaaccttttg
     6061 gatatatacc atgtgctgta ccaattgcaa tagctagtgt ttctactcct gttttttcaa
     6121 caaaatcctt agctaatttt gaatctgtat atattatttc atcagtacca ccttcacttg
     6181 atgttcctgt tgttcctatt gttccaagtt ctccttctac ggacacattt aatccttttg
     6241 ctatttctac tatttcccta gatatagcta cattctcttc atatggtaaa tgtgagccat
     6301 caatcattac tgatgtaaat ccacatctta ttgcccttaa tatttgttct ttattttccc
     6361 catgatctaa gtgtattacc ataggtactt tactcttatt tgcttcttct atgcaactag
     6421 ctacaaagct atctcctaga aaacttagct catttgggtg tattgcaagt attactggtg
     6481 catttttttc gttagcactc tgtactactg ctttaagtat ttgcccactt cctatattaa
     6541 atgctggtac agcaaattga ttttcttgtg ccacttttag catttccttc atatttatta
     6601 acatattgta cctcccgata ttttaaattt taggttgaat ttgcttcttg ttaattttgt
     6661 tgttgtttat atttaaataa tatcagggta atgaagatca gaaaataaca atcgttttcc
     6721 ttagtgaaaa ggaactttta ttatacactc taagttcctt ttcactaaat aatttttaga
     6781 agtctgcatc atagttaatt atatttctca tatacatctt ctctttttaa gtgttttatg
     6841 ctttagcctt cttaactctt tccaataaac aattagatag tttagctata aatttaaaga
     6901 tattcgtatc gtagttagca ctatattgga atcaaaaaaa ttaaaaagat actagatagc
     6961 agataccaat tattaataca ccataagtca tagatacttc tatcttaaat tcttgcatat
     7021 tagttacaat agaaattaaa taggactatt ataaaaatcg taaggtaaga ctgacattta
     7081 ttctccaact atacaaatga atactaatat agctccttct aattaaatca tactatataa
     7141 atcatatata tcccaatttt taaccttacc tctttatatt tactttttaa taaaaaaaga
     7201 tattgactaa atagtcaata tcttttagtg gatttaaata cccacgattt taatctaatt
     7261 tttaatggtt tccttaacat aatcttataa atattaaaat ttatctacct ataaaatttc
     7321 tccattaaat tttattacat ttttatacca atcaaaagat ttctttttat atcttttaag
     7381 agtcccactt ccatcattat ttttatctac atatataaat ccatatcttt ttttcatctc
     7441 tcctgttgta aatgatactg gatctataca tccccaaaca gtatacccta taacatcaac
     7501 accatcaatt tcaatggcat ttttcatttc ccttatatga ctagccaaat actctattct
     7561 ataatcatca tctacagtat tatctgattt taatacatct tctgctccaa atccattttc
     7621 aacaatgaat ataggaagtt catacttatc atatagttga ttaaggtaaa accttagacc
     7681 tacagggtct atattccatc cccaatcaga aatttttaag tatggatttt caactacatc
     7741 agcctttcct gccgagtcat tacctgttgt tttcatagtt ttatcagctg ttactacagt
     7801 agttaaataa taactacatc caataaaatc aactattcct tcttttagga tttttttatc
     7861 ttcctctgta atatctaaat tataattttt tctttcccat aattttagtg tatgtcttgg
     7921 ataatgacct cttacatgta catcagtaaa cataagttgt tctctattag attctacaaa
     7981 tttaatcata tcctctggat tgcaagaata aggataactt ggcatagctg ccaccataca
     8041 tccaatttta aactcagggt ttatttcatg acctatcttc acaacctttg cacttgctac
     8101 aaattcataa tgaactgctt gatacataac ttcttctttg tcttcctgct cttcatagat
     8161 tattcccgag ttagtaaatg cataaatagg atttgtagtt atactttgat tatttatttc
     8221 attgaaagtc atccagtact taactttatc cttgtatcta ttcattacca cttcacagaa
     8281 gtttacaaag aaatctatta attttctatt tctccatcca ccatagtttt ttactaaatg
     8341 ataaggcatt tcaaaatgac ttaaagttat tactggctct atattgtatt ttaataattc
     8401 atcaaataaa tcatcataaa atttcaatcc atcttcattt ggagttgatt catcgccctt
     8461 tggaaaaatt ctagtccaag caatacttgt cctaaaacac ttatatccca tttcagcaaa
     8521 taatctaata tcttctttat aattttcata aaaattaatg gcttcatgat taggataatt
     8581 taaaccctca attactccat ctgttatctt tcttgaaata gtatgagtac ctgcagtcat
     8641 cacatctgca atacttattc cttttccacc tttattatat ccaccttcaa cttgatgggc
     8701 agcaactgcc cctccccata aaaattcttg attagatttc atagaaatat ctcctccagt
     8761 ataattaata aacaactttt attacaggcg ttccaatttt aatatgttta ttttctttaa
     8821 ctattacatc tgctaaatca tttgtgttag ttagtattat tggtgtaaca atactatacc
     8881 cttcaccttc tattttatcc ttatcgaaag aaacaatcct atctcctttt ttaactttat
     8941 ctcctgcatt catatgagta gtataatact ttccatctaa catagtagtg ttaagaccta
     9001 cgtgtattaa tatttctaca cctttatcag aggtaattcc tattgcatgc tttgtaggaa
     9061 aaatagttgt tattgttcca tttacaggag acacaacttc tccctttgaa ggtattattg
     9121 ccatgccatt acctatagtt cctgatgcaa acacttcatc ttctacttca gataactcta
     9181 tttgtaagcc ttctattgga gataatatct cctctatacc atcatcttca tcaaaagcaa
     9241 cttcttcatt accttcttca cattcttctt tactcaatcc aaagaaatat gacaatactg
     9301 ctcctagcac taatgctgtt cctattccta atatatatcc taggaatggt gtataaactg
     9361 gcattgagaa tatattatga aatacatatg cattacaagt aacaccaaat acaccacata
     9421 taccaccacc aatacctcct gcaatagcca atactggaat cattcttctg tatcttaata
     9481 taattccata aattataggt tctgttactc ctgctaaaat tcctgtaact gctgttgaac
     9541 ctgctaatac ctttaattct gaattttttt tagattttct aaccttcata aataaaccta
     9601 ttgcaatacc tatttgagca aatactgctg caacagctgc accttctatt gggtctccac
     9661 ccattgtagc caagttttgc aaagtaattg gtgtgaagcc ccagtgtagt cctaatactg
     9721 ctaagaatgg catagctata cctattgcag ctcctgcaat tactctgtta aattcaaata
     9781 atcccataaa aatattagat attatatcac caacattagt tgctattggt ccaaataaaa
     9841 tcacagttaa aggaaccatg actaataatg atatcatcgg tactaagaat aattgtaaat
     9901 cctttaatat aatcttcttt aaaagcttat caacatagta ataaataaat atagcaacaa
     9961 atatagggaa tacaccaaaa gaataatcaa ttgctgttac tggcatccca aaaaagttag
    10021 caccaccttt tgctccaatt aaagctgtaa aattaggatc taacaaagct gctcctatca
    10081 ctccaccaac atatggattt gcactaagtt ttatagctaa ggtaatacct aagaatattg
    10141 gtaaaaagta aaatacagca tttccagctg ctgataatat agcataagtg ctacttgtat
    10201 cagacatcca tttcatagta gttagtattg taagcagtgc cttaatcatt cctgctccag
    10261 ctagtgcagg tattaatgga gaaaatgcac ctgaaattga ttcaaatatt ttagaaacta
    10321 ttgaaacttt ttctccctgt tcttcagtat tttgtccttg taaaactgct ttttttataa
    10381 tagtttcaaa gtaatcagtt actttatttc caattaccac ttggtattgt cctccactat
    10441 ttactacaga tagtacatcc ttcattttta ataactcttc tttgttagtt tttgaagtat
    10501 ctttcagctt aaaacgtagc ctagttgcac aatgaactaa actaataata ttttcttttc
    10561 ctccgacata ttttataatt tcttcagact ctctttcaaa tttcatacaa tctatcctcc
    10621 attttcataa ttttatgtat aaaaatagac ctaaatcaat acaattagat attaaaaact
    10681 aattatacca acttaggtca tgcctgccaa acagtaacaa tcctacacta tttactttat
    10741 atttgataat ctatttaaat gcaatgttaa gtacaacaat tcattttcgc taattttcca
    10801 tttatacgtc ttttcaagaa agttttttac tttttttgca caattgtaat cacttttata
    10861 tttcattttt attatatcta acaatgatgt gtctacattt gtattctcac cacttaattg
    10921 cctttttata aaacatctta aatgacttat aaaccttgtg tagtcaaagg aatattcatt
    10981 tatttcgatt ccatagtgat actttatgat atctaataca ttatcaatta tcttagttaa
    11041 caataaagtt tcttgcatat cttttgtttc taactgagca tttgcaaagt gtatcgtaat
    11101 aaatgctatt tcagaatcag gaatattttt atctaatttt tttcttaaat attctacagc
    11161 tttcttacta aaattatatt cattaggata tatttgtctt atttcccatt gaagcgggct
    11221 ttgaaatact aatccttcat ccattctttt taacatataa cttatatgtt ctgataatgt
    11281 gattaatata ctatcattaa gattatcacc caattcttct cttcccattt gaataatttc
    11341 acttacaagc tcaacatctt ttaaaggtat cctatctagt agtgaatgta attcacttaa
    11401 tgattcctca ttattgaata taaatttctt ttcaatttta tctatttcaa ctaaatcttt
    11461 agtaaattta ttaaatccaa ttccttttcc cattaatatt acttcttgtc ctgaattatc
    11521 tctggcaaat acaacattat tattaaatac tttctttata accataaact acctccactg
    11581 taaacaaaaa gagacctaaa aaagactaat aatactttaa gcatttacta gaatttttag
    11641 gtcacgcctg attacatcta tctcagtaac gatccgttta tttatctgta tgataacttt
    11701 attttcatta taaaataata actgtactta gtcaatatat aatttcatgt atatctctac
    11761 tagattattg tcataagtat tcactcattc tacttttttt atatgattta tataatctaa
    11821 acatgctaaa ataagttttg aagttatttc ataacaaaat taaggtcata tattttttat
    11881 tatatatact cgattattta tccatatata aggaaatcct ttattttgta actacaataa
    11941 ctgcctaagt tttgattttc ttttatcttt tacttctcct tattaaaaaa taattctttt
    12001 actgttgtat ctaaggctct aaacagttta atcatcaaat cattgtttgg attattaacc
    12061 ttacctaact tactatatag ctttttaact gtatatcttt aatagacctt ttggtatgct
    12121 aatccatttt ataacactaa ttcttgaatc aagcatatat tacccttaca aagcatatct
    12181 tataccctct gtagagttat gatagttgat gaacctgaag aaattaccct tacaagacat
    12241 atctgataca acctcactta ttagtttata tgtttcagaa gtatataaat aacacatact
    12301 tacttccaaa ttcttaactg ttttcttaga aaattctaat atgatttcct tacatagcga
    12361 ttataacagt gtcttattag atttcataaa attatacatc ctctttacat ttaaacttta
    12421 aatttttatc tattgtttat taattaactg tatattcact attttttatc atttataata
    12481 ctcttcttat tatcttaaaa caattataat ctaaccttaa tcacatatta tataaatatt
    12541 tttaataaac ttaataatta aataactata tttcattatc catcttataa atgtttataa
    12601 actttccact attcttcttc aataaattca aacaaatttt ctactgtagt atcgaatact
    12661 ttagcgatat ccatagctaa cttcaaagaa ggattatatt tcccattttc taagtgtaca
    12721 atagtctcac gtcttacccc aaccaattta gcaagttcat tttgcgtcat aaggagtttt
    12781 tctctgtatt ctttaatttt tgttttcatc aatattgcca cttagttaca tatccccctt
    12841 ttatcaaagt atatatacaa cactaattta gataaagact gtataaataa aactgcaatg
    12901 aggattatac ctgtatctag gtttgatata tttatattac ttgtataagg tgttgcaaag
    12961 aaaatagata ttattactat agaatatatc attattttta ttgcaatctt attaaccttt
    13021 gatagtataa attcagatga ttcatcaact aaatcattat attttttatt ataaattgaa
    13081 taacatccaa aaactattaa ccaactcaac cctggaagag aagcagtgct tggaccttta
    13141 aaaatatatt tagtagctaa tacagctata aaaaaataag ttattacaag taattccaag
    13201 atgagctttg atcttacacc agtttctgat ttagacatat aaaatcactc cttaaaagtt
    13261 atatattctc tatatttttt aatttttgtt ttcataaata ttattactta gttacatatt
    13321 ccctttttat caaaatatat atacaaaatt aattttgaca aagattgtat gaataaaact
    13381 gctaagagca ttatacctat atccaaattt gatatgtcca aagctcttgt atgattaact
    13441 gaaaagagaa cagctattac aaacatagag tataacatta tttttgatgc aatctgatca
    13501 acctttaaca acataagttt tgatgcctca tcaactaaat cattatattt tttattatac
    13561 atgagattgc acacccaaaa agctaataaa attataaaag taaaccaaat accttctcct
    13621 ttaaaaataa acttttgtaa taacaagtct ataaaaaaat aggatagcat cattaactct
    13681 gaaacaagat ttgccttaac accaagctct gatttagaca tataaaatca ccccttaaaa
    13741 gttatatatt tataacacct tatgttataa atatataact tttccaaata aattgcaata
    13801 gaatattgaa aatattcaat aatatcttca taaatatatt ttataaaaga ttttataata
    13861 aacattacaa tacagtacta aattagttta tttcatctat catctcaatc atatcattta
    13921 ctaactatta ttctaatgag catataacat tgaaatttat aattatacaa cctaaatgcc
    13981 tcccaatgta ccctcaaaaa catcatttcc tgtaactgaa gtataattgg tatattttat
    14041 cactgaaata aaaaaacact agtcaataaa gactagtatt ttcaagtatt ttatcattct
    14101 ttttttaatt attggagacg aatcatcaga ataatgccca taatttatct atatgcaaat
    14161 tctaaattta aaataaagtt tcagatgaat ttactattct atgctatgat acaacagaaa
    14221 aaactgaaat ctatgagtgg tagcttcata taatcctagt tcctacagta atcaaaactg
    14281 aggtttattc tatatgtaac taatgataaa ttttattata ggagttatta gctctatttg
    14341 tgttactata agtagtaatt atatatatga taatttttta acacttttct gttggctata
    14401 tagaaagtgg tttagaattt aaatttaaat aaaatttaaa ttcaccaaaa agaaatctat
    14461 attagaaacc actactctat tccaccagat tgtaattttt tgttctttat atcacaatgc
    14521 tataccatat taaattgaaa aataaatttt aaatttattt gttacaattc attaattcaa
    14581 aaaaatattt tgagtcatga gttttgtaaa gatttagcca tgaatttaat gcttctgatt
    14641 caaaaacatc taaaagtttc aatacttgaa acgtaaattc caacggagcg attcctgaag
    14701 ccgtaactaa attttcatca ctaactacag attccgtttt ataatatttt tctccagagt
    14761 aatttggtat taccatttta agaaactcta agtcattact tgtatgattt ctaacatcta
    14821 atagcccttt tttagctagg cctaatgtag ctccacatat ggctgcaact atagaatctt
    14881 gtattaaagc ttctttaact ttttctaata ttatctcatg attcatggat aaccaagtat
    14941 ttccccctgg caaaattaat aaatccttac tttccatatt aaactcatca actgtaattt
    15001 caggtaaaac ttttaaccca cccattgtta taataggatt tttatcaatt cctacagtaa
    15061 ttacttttag tggctttaat ccttttttaa aatatcttcc tgtatttaat tcagcagtta
    15121 aatatgccac ttcccaatct gacatagtat caaatacata catatatact tttctatttt
    15181 tcatcttttt tactccttat gtaattaatt tatatatcta attataaaat aacttaactg
    15241 acatattcag tcagttaagc tattaaattt gataataatc aattaattct agtaaatctt
    15301 caattatttt cttcctaagg cttagtggtt caattacttg tattgtcttt ctataaggta
    15361 aaagtatatt tggtatgtac ttgcatatta cttcctcttc gagcataaat attattttat
    15421 taggtgttct ttctttcaag tagtgcccta aaaaccaatg ttggcttaaa ctatctaaag
    15481 aatctatact cccttctaca actaattgaa ttatattttg ttcatctttt atttcaggta
    15541 taattccttt tataaaaaat tcacttgctg aaaattctgt cggtctgtta aatgtatttg
    15601 atgtttctat gatttcacta atcctatcca ctctgaaact acgtacctca tttctcatat
    15661 tacaaaatgc aactacgtac caattattat tccagtgaac aattccatat ggatttataa
    15721 ttctatattt tgattttgct ttacgacctg catgatagtt gatttctaca gatagctcct
    15781 ttaatatact attctccaat tttttaagta ctgattctat agacactttc ccaattggtt
    15841 ttattacttc aagggctctt aagtggtttg ttaaaatatc ttcttggttt tgatttgaat
    15901 acatttttaa ctttaatatc gatttatcta atgcttcgtc taagaagtat ccttcttttt
    15961 tagcaaatag agctgcatga agtagagatt tttgctcttc tatatcaaaa aaaagaggtg
    16021 ctttagtaaa attatttaaa aggctatacc caccattatg acctgtatct gaaattatag
    16081 gtactccact cgcagaaagt acatcaatat atcggtacac tgttcttata tttatttcta
    16141 atttttcagc tatctgtttt gctgtaattt ttttgtcaga gtttaacatc cacagtatag
    16201 acatcatatt gtcaatttta gccatgtagt ttcacctctt tctatttgtt atataaagtt
    16261 attatataac tttttgattg attttttaca aaaaaacatt agtaaactgc taataattta
    16321 tactaagatt tatttcaaat atttatagat agtctttttc tatagttaag ttatccatta
    16381 aattacatag tagtatatcc attttagttg atatattttc agctacctcc cttgaatatt
    16441 attacaataa gtctaaatct tctttcttcc ataaatatat tatgaggaaa gactatcatc
    16501 tttaatggtt taatagtata aaagatatta atttaaaaaa atctattttt atatcagatg
    16561 ggtattgttt tttataaaac tgaaaaaatc acctaataga atctatgatt ttttaacata
    16621 acctccataa attagtacca attatcactt caaattcaaa tttttatctg aagaatatac
    16681 aatcatattt ccatactcaa cataatattg agtgtttggc ttgtatttac aaattattat
    16741 tctaacaaaa acaactatac atagattaaa atcaccttct aaacataatt attaaaattt
    16801 aattaatgat atcaattcca ttaatctctt ttaataaaaa attctctttt ctatatgaaa
    16861 attatttcaa aacttttaag ttaaatacaa aaatgactat aaatagattt ttatttacac
    16921 aaatctattt atagtcacta tagtttatcc aataaaataa taaaataaat atgtacacaa
    16981 taaatgttat ttacgtctta agtatttatt tgttagattt ttaattaaaa aaaacaagct
    17041 aatgaacatt aatgctaaat ctagcattat attactttga tctcctgttt gtacattttg
    17101 acctacatta ctatctaaac tttcatctgt atctatattt atatctggtt ttccattccc
    17161 atctgtatct atatttatat ccggctttcc atccccatct gtatctatat ttatatccgg
    17221 ttttccatct ccatctatat ctatatttat atctggtttt ccatctccat ctatatctat
    17281 atttatatct ggttttccat ctccatctat atctatattt atatctggtt ttccatctcc
    17341 atctgtatct atatttatat ctggttttcc atctccatct atatctatat ttatattcgg
    17401 ttttccatcc ccatctgtat ctatatctgg tttgctattt cctccattat ctgggtctgg
    17461 tttactattt ccaccgttat ctggatccgg tttgctattt cctccattat ctggatctgg
    17521 tttaccattg ccaccgttat ctggatctgg tttgctattt cctccgttat ctggatccgg
    17581 tttgctattt cctccattac ctgaatccgg tttgctattt cctccattac ctgaatctgg
    17641 tttgctattt cctccattac ctgaatccgg tttgctattt cctccattac ctgaatctgg
    17701 tttgctattt cctccattat ctggatccgg cttgctattt cctccattat ctggatctgg
    17761 cttatttaga tttggattac ctgtatcata acctcctgag ccagtatcta catttttatc
    17821 aggcttccaa taatcatcta ctccatcatt atctgtatct attgctggac gattataatc
    17881 tgtatcaggg tttccatctc cattggtatc tatattttta tcaggtttcc aaataccatc
    17941 tccatttcca ccttctgtac taggcttcca ttcacctgta ttatcagtat ctatgttaat
    18001 atctggcttc caatcaccac tcgtatctat attgatatct ggccttccat caccatcagt
    18061 gtctatattt atatccggta ttccatcccc atctacatct acatttgtca tatctaactt
    18121 taacttcttt tcatcctcac taccttcaat gtaatttata tcatctccaa tatattttac
    18181 agtaatagtt tgttcagtag taaaaatatg atgattgcta tctaaaggtc tccattcaat
    18241 agatgcagta ctataattat gactctcact acccttatta tgagttttta attctactgg
    18301 atctttatat tcctttccat taatatagaa ttgtacgtaa cctcttggag aggcacaatc
    18361 tggtccttct ttcttatctg gtgaaatagt aacatttaat gtaaacgtat ctgttggttt
    18421 aaaaacatca gttttagctt tagactcttc tacaactaat gaagtttctg tatcagcagg
    18481 aataatttct gccttataat atgctctatg cccccaataa gcttcattaa aaggatatac
    18541 atttgaaaac tgtgttgatg taatgcttaa ttgatatttt ccagcatcaa cttgctttgt
    18601 aaggtcatca cttcctaaat ttgtatctgg ttccattgtt tcctcattta aacgttgaga
    18661 actaatagtc ataaattttt tatctgtgag tttttcacct ttaggagtaa ttattggaat
    18721 acccccatct tttaatatcc aatctaaaaa taatttttct acatcttctt caaatggtaa
    18781 tccatcatat cttttaataa tcaaatatgg tggagtatca tcaatagtaa attcttcata
    18841 ttgctttaaa aattgagaac ctgaacctat atctttaaca taaaaatcat ctggttttat
    18901 atttcctcca gtaattttat ctataacaac taaattaaca gatacttcag atcccttaaa
    18961 ttgatcagaa aaccataagt aaagaacccc ttgatcatct gtataactag gtgctccata
    19021 aggataaatt tttccatcaa ttagcatttt aaaatcatca actaatgtag tactaacttt
    19081 atcttgtcct aaatacttta aagatatttt attcataaaa acttttgttt tcttttctaa
    19141 atcaccgtat gcaactgctc cacctaaact tttgaatgtt gttgctttta atgaaccacc
    19201 tgttactata acatctcctg ttgtagcact taggtcaaaa atccaatctc ccactcctgt
    19261 catataaggt aaaatcgttc ctccagttac aagtatacga tatcctctat ttgttcctgg
    19321 attaacacat ccatccccaa atgcactacc atgtgcacct ccatatgaat aggaaagtcc
    19381 accattaatt gtaatatttc cactataacc agaacctgtg ctaggatcta ctactgaggg
    19441 acttaatgca ttctttgttg ttgtatagta tcctccacct attccagctc catggtatgc
    19501 acctttagca gttatagtac caccattgat tgtgatatct ccaccactac cattaccgcc
    19561 tccacctatt ccagctccat atcctgtatt acgactcgat tcttgaccta tagcagttat
    19621 agcaccacca ttaataataa tatttcctcc actttcagta tttccaccgc caatacctgc
    19681 agaataataa tttccaacaa cttttaaact tcctctatta ttactatcta gtagtgtaag
    19741 gcgatctcct ttttttaact tgtctccatt ttctagagtt acatctctag gaatttttcc
    19801 accctcagga actataaact ctccttcaat atctctattt acaacagaat catcaatagt
    19861 tagagtagta ccttttcctg ctctcatacc tggataatat acatcacctg actctagctt
    19921 gttttcacta ccatcttgta atataacatg tgcatatgca ccaccatctt tatctggtgt
    19981 taaagtaaat gggctattag atgcagtttt aatatttact ccatcaaata ttaattcagc
    20041 ttttacatct ttaggtataa caatcctatg tgttgttgga gtatttggat tattattttg
    20101 aattgtcatt tgttttccac taagaatagt taaaacgcca cttgcaaatt taaaatcgac
    20161 atttatttct ccaccactaa ttttaaagtc tcctacagat gtaggatctt ctgcagtggc
    20221 ttcttccaca actaatgcat tcatatcttc ttctgcattt cctgcattag aatcttcttc
    20281 tgcatttcct gcattagcat cttcttctgc atttcctgca ttagcatctc cttctgcatt
    20341 tcctgcatta gaatcttctt c
//
LOCUS       DAMJVG010000070        20107 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.070, whole genome shotgun sequence.
ACCESSION   DAMJVG010000070 DAMJVG010000000
VERSION     DAMJVG010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20107)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20107)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20107
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.070"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            168..1361
                     /locus_tag="PC512_002778"
     CDS             168..1361
                     /locus_tag="PC512_002778"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase"
                     /protein_id="HDF2442511.1"
                     /translation="MDTLKELFKIGSGPSSSHTMGPQRAAERFKNENPDAESFRAILY
                     GSLAATGKGHLTDYIIEKTIAPKKVEIVWEEDIIKDFHPNGMKFEALDKDKNVTAEWT
                     VYSVGGGTIAEEGQRNSKSNSIYHLDTMDEIVKWCKENNKTLVDFVLECEPKDIKDYI
                     KTIKDAMRKSIDDGLSTDEIIPGKLLLKRRASTFYNAYKKDKSFSTLVYAYALAASEQ
                     NASGNIIVTAPTCGSAGVIPGIFFAMQDFYNYDDEKIIEALLVAGIIGNIIKTNASIS
                     GAEVGCQGEVGAACSMAAAAVAYLKGGTIDHIEYAAEIALEHHLGMTCDPVYGYVQIP
                     CIERNAMAAQRAYDAANYALLTDGSHSVSLDQVVETMKETGIDMMDKYKETAKGGLAK
                     HFFSC"
     gene            1567..2685
                     /locus_tag="PC512_002779"
     CDS             1567..2685
                     /locus_tag="PC512_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HDF2442512.1"
                     /translation="MREASYLQEQLYKHRKSLNPIAEIGRKEYKTSKYIRDYLDKLGI
                     EYEVYLETGIVGVIEGKRPKKDIAFRADIDGLHSEEGVKHLCGHDGHATILLGLIEYL
                     NDNKEDLNDNIVFIFQPAEEGPGGAKALIDEGVLRKYNIDEIYGLHIYPELPEGYVGT
                     REGYFMAQIGDIDIEIVSKSGHGAMPQNGIDGIVIASNFVSSLQTIVSRNISPIDNAV
                     LTIGRIEGGARRNIIAENIKMEGTMRCFSPEVYEKMKLRVRELARGFELAYNCKVNIN
                     IIDDYIAVKNDKDLYQEFVEAIGSDTVVELEPLMISEDFSYYQKEVPGLFFMLGSRNE
                     EKGFVNGLHNINFNFDEKICVNALNVYSKLLKYKEAID"
     gene            2816..3061
                     /locus_tag="PC512_002780"
     CDS             2816..3061
                     /locus_tag="PC512_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small, acid-soluble spore protein, alpha/beta
                     type"
                     /protein_id="HDF2442513.1"
                     /translation="MKEKVQREKKITNGKNTKILTNDDIMKYEIASELGLMDKVGERG
                     WAGLTAKEAGRIGGMLTSRKKRLKKIVEEQNKKDESI"
     gene            3048..3794
                     /locus_tag="PC512_002781"
     CDS             3048..3794
                     /locus_tag="PC512_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDF2442514.1"
                     /translation="MSQYSDFAFVYDELMNEVDYNGWVKYIEDIIDSEGVKVKNILEL
                     ACGTGNLTIPLTKKNYDIAGIDISDEMLSVAREKSEKEGVELVLLQQDISELDFEISD
                     LDCVLCACDGFNYITYDDDLENVFSKTYELLKKDGIFIFDISSFYKLANILGNNMYGE
                     NREDIAYMWQNYFDEEENLIEMELTFFIKDECGKFERFEEIHQQRAYTEDEIVDMLEK
                     SGFKDIKYYGDFTFDKPSEESQRIFFVCKK"
     gene            4079..4954
                     /gene="hslO"
                     /locus_tag="PC512_002782"
     CDS             4079..4954
                     /gene="hslO"
                     /locus_tag="PC512_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HDF2442515.1"
                     /translation="MRDYVLRATSGNGQVRAFVATTRNTVEEARRLHETTKVATAALG
                     RTLTATSIMGLMMKNDSDKLTVIIKGGGPIGTIIATSDSKGMVKGYVGNPQVEVEDYP
                     NGKLNVAAAVGTEGVVKVIKDLGLREPYNGTYPLVSGEIAEDFTYYFAVSEQTPSVVA
                     LGVLTKEDEVEFAGGFIVQLMPDAEEETIAKLEENVAKLPSITNMLKEGKSPEDILNI
                     VLDGLEPKILDTCEVGFMCECSKERVKTALVAIGKKSLAQIIEEDKKAEVGCQFCNKK
                     YMYSEEELLEILKEM"
     gene            5345..6145
                     /locus_tag="PC512_002783"
     CDS             5345..6145
                     /locus_tag="PC512_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HDF2442516.1"
                     /translation="MESKTKYIGISILILLMIFLIAKNFNGKLEIPIPESNSRKFKSA
                     AVFYPQHQDDEVLWGGSAIVDAIKQCGVDNVYVVLVSDGSGVNVFKANTKFRNLTRKQ
                     KEELRNNEFKSALRELGVKPQNVIILADIDKKEGTHYELMEKTILDFEHKFKGNVTHI
                     AHHYKYDDHIMHRKNGEVLKKLKREGKIKDDLYFVKPKYVKYIPRNERAIYKAMDFDD
                     YNKVKSACYEYKVVNSKRKMYGIGYISAHSYFEHLLNDPELTSVLSED"
     gene            6672..8912
                     /locus_tag="PC512_002784"
     CDS             6672..8912
                     /locus_tag="PC512_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HDF2442517.1"
                     /translation="MNNEFIILKGCKENNLNNISLKIPKRKITIFTGVSGSGKSSIVF
                     ETIAKESQRQLNERFSTFVRSFLPKYGEVKADCIENLSTPIIIDQSRLGGNSRSTLGT
                     ITDVNSFLRALYSRFGSEYIGNANMFSFNNIDGMCPHCHGLGKKLVPNMNQILDMNKS
                     LNEGAILLSGFGVGSWHWNIFAESGFFDINKRICDYSEVELEKFLHGKAEKIKIENAG
                     QTNMTYEGLMVKFNRLYLSREGEISEATKKKLSKLLIEDRCPICDGRRLNERVYRSLI
                     NGYNIADLTSMQIDELAEVIKSIDEPEAQPLIKGIIEKLNSIIDIGLGYLTLDRETSS
                     LSGGESQRIKMVKYLNSNLVDLMYIFDEPSVGLHPKDVYKLNNLLKKLRDKGNTIIVV
                     EHDPDVIKIADHIVDVGPKAGKYGGEVVYEGSYENLLTSGTLTGNALSKFLPIKESVR
                     EHSGYLEVKNCNKNNLKNVSIKIPKGVLTLVTGVAGAGKSTLIKDEFLKQNPSAVLID
                     QSPVSANSRSSLATYSGIMNNIRSIFSKTNGVNASLFSSNSEGACDNCKGSGIVEMNL
                     AFMESIKSTCNVCEGKKFKKEVLEYRFQGKNIIEVLEMSVLEAIEFFNLKQIKTKLQC
                     IEKMGIGYLTLGQTLDTLSGGECQRLKLASELNKESSVYILDEPTTGLHMADIENFIS
                     IIEEIVDNGNTVIIIEHNIDVIKRADWIIELGPEGGTKGGRVIFEGIPKQLCNNKISL
                     TAKYIV"
     gene            9326..10861
                     /locus_tag="PC512_002785"
     CDS             9326..10861
                     /locus_tag="PC512_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HDF2442518.1"
                     /translation="MINDILTLLSERSDFFIKLSIEHLMISIISIIIAIVLGGIIGII
                     VSEFHNSSKPILGTINFLYTIPSISMLGFLIPFSGIGNTTAVIALTIYALLPMVRNTY
                     TGITNVDKNILEAARGMGSTDFQILYKIKLPLALPVIMSGIRNMVIMTIALAGIASFI
                     GAGGLGVAIYRGITTNNTIMTITGSILIALLALIFDFILGLVEKFFQRKRKKKNRKKV
                     FAILGSLILIATIFTSYLFNPSKTQTIHIATKPMTEQYILGEMLDILIEKNTGLNVEI
                     TQGVGGGTSNIQPAMENGEFDIYPEYTGTGWNMVLKKNELYTESMFSKLQSEYKTKLK
                     MQWTGMYGFSNSYALAVRKEVADKYNLKNITDLKDVSSKLTFGAEYDFYEREDGYTPL
                     CNTYGLNFKDTVDLDIGLKYQAINEGKIDVMPIFTTDGQYSVSDVVVLKDDKNFYPSY
                     QCGNVVRLEVLEENPELSKVFKMVGDILTDKEMAKMNYDVENNNLEPREVAREFLNKK
                     GLL"
     gene            10877..11638
                     /locus_tag="PC512_002786"
     CDS             10877..11638
                     /locus_tag="PC512_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2442519.1"
                     /translation="MTPIIQFKNIKKQYNDKTIIDNLNLDIEKGEFLTVIGSSGSGKT
                     TLLKMINGLILPDGGNILINQTDIKNEDLIKLRRRIGYCVQGSVLFPHMTVEENISYV
                     PNLLSKKNKLEVKSAVNKWMEIVGLPNDMKVRYPSELSGGQQQRVGIARALASSPEIL
                     LMDEPFGAVDEITRKQLQKEIKEIHKKTGVTIIFITHDIYEALILGTKTLVLNHGVVQ
                     QYDTPENILNTPANQFVDQLLNIRKSIIDDDNLKE"
     gene            11976..12845
                     /locus_tag="PC512_002787"
     CDS             11976..12845
                     /locus_tag="PC512_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF2442520.1"
                     /translation="MDNNLITIEKTLDYIEKHLLDEMLDLNVISKEIGYSKYHLHRMF
                     TSVVGFSVHNYIQRRRLTEAARMLIFTEKPIIEIALISGYDTQRSFSRGFKKMFKRSP
                     NFFRRHQDFLPLQLKFDIHNRKKLRGDMVLDVKKVNCADINIVGYSGKVRKGFHIIGK
                     CWRDLHKNKEMIENKVDLGFLIGVSDYSNFKEIENTPTFTYIAGAQVATFGKLPNGME
                     KFVLPKSNYIVFTFIGKNEDSMQNVVEYIYQEWFPNSSCQFNENNLYDFVKYGEKTDE
                     NGLSEIQFWVPII"
     gene            13174..13425
                     /locus_tag="PC512_002788"
     CDS             13174..13425
                     /locus_tag="PC512_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3781 domain-containing protein"
                     /protein_id="HDF2442521.1"
                     /translation="MNVENELLKNLDRLHTTELGVVRIKKNLSLETNDVVNWCKTKIE
                     SPNAIINRKGKNWYISVYDCIITVNAHSYTIITAHKEKK"
     gene            13537..14316
                     /locus_tag="PC512_002789"
     CDS             13537..14316
                     /locus_tag="PC512_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDF2442522.1"
                     /translation="MNDTVKEKLAESLTSDTTDILPYLPYLLQDFWELGSSPEQMLQL
                     FRKHIPFNEDTKVLDLACGKGAVSVKLAKELNIHIKGIDLIPEFIDYARRKAIEYKVD
                     ALCDFEMNDANSSVKIEHDYDCVIFGAVGDILGNYKETISKLLPTIKSKGFILIDDAY
                     VVDKSTNEQLNFERVYPTYNEWCILFKELGLKLIECIPCLELENDVEEEMNWIITRAN
                     ELIKKYPSQKDMFEQYVISQKNEYTDLQQDLVGATWILQKE"
     gene            complement(14451..15101)
                     /locus_tag="PC512_002790"
     CDS             complement(14451..15101)
                     /locus_tag="PC512_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442523.1"
                     /translation="MNIVMINGSPKVNKNNSQYFLSELKQLIQNDNKVFTFKVDNTSK
                     YPDALNAILNCDRLIIASPLYVDGIPSHLLHFLEKCEKFLKTQNKKPIPVYAIVNCGF
                     NEGEHNHLAIQMIEHWCKKINFTWVQGIGIGAGEMFGSLESVPLGKGPKKDLGIALKE
                     LSKNILSDNIHIDDSNKSTIFISPNFPRFLYKLMGNHQWNTQAKSNGLTKSDILKK"
     gene            complement(15098..15601)
                     /locus_tag="PC512_002791"
     CDS             complement(15098..15601)
                     /locus_tag="PC512_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF2442524.1"
                     /translation="MRLLIHDLTDKELEKLLPKLDDNIKILPNTKEIHKCIGCFGCWI
                     KTPSECVVKDYYSNMGKLINDSDGIIIISRCCYGGFSPFVKNVLDKSINYILPYFVIK
                     DNMMRHKSRYDKQINLKAIFYGDCITEAEKETATKLVNGNAINFNIKEHSVCFYENIQ
                     DIRGESI"
     gene            complement(15650..16165)
                     /locus_tag="PC512_002792"
     CDS             complement(15650..16165)
                     /locus_tag="PC512_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDF2442525.1"
                     /translation="MLEYIILGFLMEKELSGYDLKQIMSESTSYFFDASFGSIYPALK
                     RLETKGYIHYHEVIDGNKLKKLYSITNTGKEVFLEWLKKPINFSKTKQDHLVNIFFYK
                     YLPKEIIETNLKMLITEVELLLNKLSKQKNDAEENHCVDQYTYMYATMIYGVDYYNFV
                     INWCKDLLKNL"
     gene            16445..16969
                     /locus_tag="PC512_002793"
     CDS             16445..16969
                     /locus_tag="PC512_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2442526.1"
                     /translation="MHEQIDCCERKKRTIDIKGENMRELLKWVSIINRYNTNYIDRKL
                     ADIGINNSQYFYVLHICNNPGITQDTIFEKILVNPSNITRALANLEKEGFITREPGVK
                     DKRTWHLYPTEKSLGCYDEILKITNGYVEELLSSFEKEEQELFMSMLKKVAFLAIDMN
                     EEAKLEAKENGRKI"
     gene            16953..18356
                     /locus_tag="PC512_002794"
     CDS             16953..18356
                     /locus_tag="PC512_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2442527.1"
                     /translation="MEEKYKEPLEYEKVSKLLTKYAIPSIIAMLVSALYNIVDQIFIG
                     QGVGVLGNAATNVTFPLTTICTAIALLLGIGGASKCSLELGAKNSEKATKAAGNSICL
                     MAVFGISLFIVVSIFLTPLLKFFGSTSEILPYAHTYTKITSIGLPFLIMSTGMSKLIL
                     ADGRPKASMFCMLIGAVINTILNPLFIFVFNMGIAGSALATVIGQLISFGISVHYIKN
                     FQHIKLHKKSFKLDSIIYKHIFALGSSSCFNQLAMTVTQIVMNNTLAYYGARSVYGSE
                     IPLACVGIIIKVNMIFISIIIGISQGMQPIIGYNYGAEKYNRVKEAYKFAVGSATIIS
                     VIAFLCFQLFPRQITSIFGNGNETYFIFAEHYFRTFLFLTFINGVQIVSSTFFTSIGK
                     SVLGLFTSLTRQILFLIPLIVILPMFMGIDGVMFAGPIADAAAAMVCIYFAVHEMKSL
                     TIKQNNLMSNHNKIAEV"
     gene            complement(18920..19231)
                     /locus_tag="PC512_002795"
     CDS             complement(18920..19231)
                     /locus_tag="PC512_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442528.1"
                     /translation="MKKIIKSFTFWFFLIALFEIYMHQIGQDSKSIVLIGLNPILSII
                     SRVDSFFVFMDSGMQIPCRTITGSISIYWYIASILSFLIYGIILDLIRIVISKIGNKT
                     K"
     gene            complement(19287..19880)
                     /locus_tag="PC512_002796"
     CDS             complement(19287..19880)
                     /locus_tag="PC512_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF2442529.1"
                     /translation="MISDSISKRRSIRKYKNQSISHETIEKIIEAGINAPSSKNRQPW
                     RFVVITEKEKESMLKAMSKGIQNEINDNGLLPGSRQHIAGANYTVEIMKQAPVTIFIL
                     NILGKSPLEKLSPEERFYEMANMQSIGAAIQNMSLTAVELGLGSLWICDVYFAYRELC
                     EWLNTDSQLVAAISLGYPDEEPSRRPRLQLSDVTEWR"
BASE COUNT         7683 a         2174 c         3563 g         6687 t
ORIGIN      
        1 tttattctca aaatatgcat attaatttaa taaaatatac caaaatggaa ataaaaaata
       61 aattttatga gaatttaata actaataatt aatatattta ggttataata aatatgtgcg
      121 taaaatctaa caataagcaa taataccgta aatttaggag gaataatatg gatactttaa
      181 aggaactttt taaaatagga agtggacctt caagttctca tactatggga ccacaaagag
      241 cagcagagag atttaagaat gaaaacccag atgcagaaag ttttagagca atattatatg
      301 gtagtttggc agctacaggg aaaggtcact taactgacta tataattgaa aaaactatag
      361 cacctaaaaa agtcgaaatt gtttgggaag aagatattat aaaagatttt cacccaaatg
      421 ggatgaagtt tgaagcttta gataaagata aaaatgtaac agctgaatgg actgtatatt
      481 ctgtaggtgg aggaactata gcagaagaag gtcaaagaaa cagtaaaagc aatagtatat
      541 atcacttaga tactatggat gagatagtaa aatggtgcaa agaaaataat aagactttgg
      601 tagattttgt gttggaatgt gaaccaaaag acataaaaga ttatataaaa actataaaag
      661 atgctatgag aaaatctatt gatgatggac taagtacaga tgaaataata ccaggcaagt
      721 tattattaaa aagaagagca agtacatttt ataatgcata taaaaaagat aagagcttct
      781 caacacttgt atatgcatat gcactagcag cttcagagca aaacgcttct ggtaatataa
      841 tagttacagc accaacttgt ggttctgctg gagtaatacc aggaatattc tttgcaatgc
      901 aggatttcta taattatgat gacgaaaaaa taattgaagc actacttgta gctggaataa
      961 taggtaatat aataaaaact aacgcttcaa tatctggagc agaggtaggg tgtcaaggtg
     1021 aagttggagc cgcttgttct atggcagcag cagcagtagc atacttaaaa ggtggaacta
     1081 tagaccatat tgaatatgcg gcagaaatag cacttgaaca tcatttagga atgacttgtg
     1141 accctgtata tggatatgtt caaattccat gtatagaaag aaatgcaatg gcagctcaaa
     1201 gagcttatga tgcagctaat tatgcattat taactgatgg ctcacattct gtctccttag
     1261 accaagttgt tgaaacaatg aaagaaactg gtatagatat gatggataag tacaaagaaa
     1321 cagctaaggg tggacttgct aaacatttct tctcttgcta aaaataaaat tttccaataa
     1381 taattcctct gttttgattt atgaaacagg ggaattatta ttaatggtga attatttaat
     1441 aatgcaaaat atttttatat tcaatttagc tttttatttt taattagtat aacatgctat
     1501 ataatatttt aattataaag aaatatagaa atatttttta ataaattaga aattggagga
     1561 gattacatga gagaggcatc atatttacaa gaacaacttt ataaacatag gaagtcatta
     1621 aatcctattg cagagattgg gagaaaagag tataagactt caaaatatat aagagattat
     1681 cttgataaat taggaattga gtatgaagtt tatttagaaa caggtatagt aggtgtaata
     1741 gaaggtaaaa gacctaaaaa agatattgct tttagagctg acatagatgg tcttcatagt
     1801 gaagaagggg taaaacattt atgtggtcat gatggacatg ctactatctt acttggatta
     1861 attgagtatt taaatgataa taaagaagac ttaaatgata atatagtatt tatattccaa
     1921 ccggcagaag aaggtcctgg gggagcaaaa gctttaatag atgaaggagt gcttagaaaa
     1981 tacaatattg atgaaatata tgggcttcat atatatccag agttaccaga aggttatgta
     2041 ggtacaagag agggctattt tatggctcaa ataggagata ttgacataga aatagtgtct
     2101 aaaagtggac atggggctat gccacaaaat ggtattgatg gtatagtgat agcttcaaac
     2161 tttgtaagct cacttcaaac tatagtgtct agaaatataa gcccaataga caatgcagtg
     2221 ttgactattg gcagaattga agggggagct agaagaaata taatagctga aaatataaag
     2281 atggaaggta ctatgagatg tttcagccca gaagtgtatg agaaaatgaa gcttagagtt
     2341 agagaacttg ctagagggtt tgaattggct tataactgta aggttaatat aaatattata
     2401 gatgattata tcgctgttaa aaatgacaag gatttgtatc aagagtttgt agaggctatt
     2461 ggaagtgata ctgttgtaga gttagagcca cttatgatat cagaagattt ttcttattat
     2521 caaaaagaag ttccaggatt attttttatg ttgggttcaa gaaacgaaga aaaaggattt
     2581 gtaaatggtc ttcataatat aaactttaat tttgatgaaa agatatgtgt aaatgcattg
     2641 aatgtttatt caaaattatt aaaatacaaa gaagcaatag attaggaaga taagttataa
     2701 agattaaaaa gcataaatac ctaaatttaa aaaaagtgta ttaataaata ccccttacat
     2761 atttgtataa atttatttta attgacaaaa atacaaataa gaaggggtga tttttttgaa
     2821 agaaaaagta caaagagaaa agaagataac taatggcaag aatactaaaa tattgacaaa
     2881 tgatgatata atgaaatatg agatagcctc agaactaggt cttatggata aagttggtga
     2941 acgtggatgg gcaggactta cagctaagga agcaggaaga attggaggta tgcttacatc
     3001 acgcaaaaag aggcttaaaa agattgtgga ggagcagaat aaaaaggatg agtcaatata
     3061 gtgattttgc gtttgtatat gatgaactta tgaatgaagt tgattataat ggttgggtta
     3121 aatatataga agatataata gatagtgaag gtgtaaaagt aaaaaatata ttggaattgg
     3181 catgtggcac gggtaatctt acaattccat tgactaaaaa aaattacgat atagctggta
     3241 tagatatatc tgatgagatg cttagtgtag caagagaaaa gtcagaaaaa gaaggagtag
     3301 aattagtttt acttcaacaa gatatatcag agcttgattt tgaaatatct gatttggact
     3361 gtgtactttg tgcttgtgat ggattcaatt atataactta tgatgatgat ttggaaaatg
     3421 tattttcaaa gacatatgaa ttattaaaga aagatggaat attcatattt gatataagtt
     3481 ctttttataa attagccaac atattgggaa ataacatgta tggagaaaat agagaagata
     3541 tagcgtatat gtggcaaaat tactttgatg aagaagagaa tctaattgaa atggaactta
     3601 cattctttat taaagatgaa tgtggaaaat ttgaaagatt tgaagagata caccaacaaa
     3661 gagcatatac tgaagatgag atagttgata tgcttgaaaa atctggattt aaggatataa
     3721 aatattatgg ggattttaca tttgacaaac ctagtgaaga aagtcaaaga atcttctttg
     3781 tatgtaaaaa ataagatatt tttgactata taagataatt attaaaaata accatgatat
     3841 aaaaatatag aaaatgcagt tttatagatt aaaagtaaag tgatgatact ttatgacttt
     3901 tattttttaa taattataaa gttctataga taaaaattaa aatataataa ctattgctta
     3961 gtaaaattaa aataaaatgg gttttgccca aggttaagat agataagtat ttatagatta
     4021 aaattaaggt agtaatataa taaaaataag acaattaacg ggacatggag gaatattaat
     4081 gagagattat gtactaagag cgacatcagg aaatggtcaa gttagagcat ttgtcgcaac
     4141 tactagaaat acagtagaag aagctagaag attacatgaa actacaaaag tagcaacagc
     4201 agcacttgga agaacattaa cagccacatc tataatggga ttaatgatga aaaatgatag
     4261 tgataaattg actgtaataa taaaaggtgg aggtccaatt ggaactatta tcgccacatc
     4321 agactctaag ggaatggtaa aaggatatgt aggaaatcca caagtagagg ttgaagacta
     4381 tccaaatgga aagttaaatg tagcagcagc agtaggtaca gaaggtgttg taaaagttat
     4441 aaaagactta ggtcttagag aaccatataa tgggacttat ccattggtaa gtggagaaat
     4501 tgcagaagac tttacttatt attttgctgt atcagagcag actccatcag tagtagcttt
     4561 aggtgttctt acaaaagaag atgaagtaga gtttgctgga ggatttatag ttcaattaat
     4621 gccagatgca gaagaagaga ctattgctaa gttagaggaa aatgtagcta aattaccttc
     4681 tataactaac atgttaaaag aaggaaaatc accagaggat atattaaata ttgttttgga
     4741 tggtttggaa cctaaaatac ttgatacctg tgaagttggg tttatgtgtg aatgttcaaa
     4801 agaaagagta aaaactgctt tggttgcaat tggtaaaaaa tcattggctc aaataataga
     4861 agaagataaa aaagcagaag ttggttgcca gttctgtaat aagaaatata tgtatagtga
     4921 agaagagttg cttgaaattt taaaggaaat gtagactata aaaatagttg tattgatata
     4981 agtaatgtta tagtgatata gtaaagtcgt attgatatag taattaaagt ataatttatt
     5041 aataatagac atatttatat taaaaaataa gtttaataaa tttttaagct taataaattt
     5101 taagaattaa gaagctttct ggctgtaatg tttgcaatgt tgcagttaga aggctttttt
     5161 attttattat agttcgtgtc aaagattgta tgaaacaata aaatattgta aaataatttg
     5221 tatatttaga cctgattggc acaaaggttt ataaggtatt tgagttgatt atgcgaaatt
     5281 ctatgaagta gtaaccctgt gactttaatc atgggaggtt cagaagaagg agaaaatttt
     5341 aaatatggaa agtaaaacga agtacatagg aataagtata ttaatattat tgatgatatt
     5401 tttaattgca aaaaatttta acggaaaact tgaaatacct attcctgaga gtaatagtag
     5461 aaaatttaaa tcagcagcag tgttttatcc tcaacatcaa gatgatgagg ttttatgggg
     5521 aggaagtgcc attgtagatg ctataaaaca gtgtggtgtt gataatgtat atgtggtatt
     5581 agtatcagat ggttctggag ttaacgtttt caaagctaac acaaaattta gaaatttaac
     5641 taggaagcaa aaggaagaac ttagaaataa cgagtttaaa tcagctttga gagagcttgg
     5701 agtgaaacct caaaatgtga ttatacttgc agatatagat aaaaaggaag gcacacatta
     5761 tgaattaatg gaaaagacta tattggattt tgaacataag tttaaaggca atgtgaccca
     5821 tatagcccat cactataagt atgatgacca tataatgcat agaaagaatg gggaagtttt
     5881 aaagaaactt aaacgtgaag gtaagataaa agatgacttg tattttgtta agccaaaata
     5941 tgtaaagtat ataccaagaa atgaaagagc tatctataaa gcaatggatt ttgatgacta
     6001 caataaggtt aagagtgctt gttatgaata taaggttgta aattcaaagc gtaaaatgta
     6061 tggtatagga tatatttcgg cacatagtta ttttgaacat cttctaaatg accctgaact
     6121 tacgtctgta ttaagtgaag attaatttct tataagtagt aagttatgtt tgataagttg
     6181 attggaattt tctatagttt tgaaggtatt ggaaatttag ttttatttaa agatttaaag
     6241 atagaggttt ttagtgttta aaattttaaa gttaagttga ataattgtat agaattattt
     6301 gtgaaagaag aaacagtgta aaacatagta tcttatttat ggttttaaaa tcataggcaa
     6361 gatacttttt ttatgtaact aataccattt tgagattatt aacttaagaa ttttatataa
     6421 tttaacactc atatataatg atgatattta ggtagaatag atgcaattac gcttaaataa
     6481 aataactgta ttttttataa aaatcaaacc ctacactata ctaccagata aaatctacat
     6541 gctataattt gacctgtgtt tataaaaaaa ggagtaatct aataaaatag tatttcactt
     6601 atgtataact aacaactatt attacgattt tctctaaata atttaaagaa aaataatgca
     6661 ggaggtaaaa tatgaacaat gaatttataa ttttaaaagg ttgcaaagag aacaatttga
     6721 acaatatttc cttaaaaata ccaaaaagaa aaataaccat attcacaggg gtgtcgggtt
     6781 ctggaaagtc atctattgta tttgagacaa ttgcaaaaga atcacaacgc caactaaatg
     6841 aaaggtttag tacatttgta agaagttttt tacctaagta tggagaggtt aaagctgatt
     6901 gtatagaaaa tttgtcaaca ccaattatca tagaccaaag tagacttggt ggaaattcaa
     6961 ggtcaaccct aggtactatt acagatgtaa attccttttt aagagcttta tattcaaggt
     7021 ttggtagtga gtatataggt aatgctaata tgttttcttt taataatatt gatggtatgt
     7081 gcccacactg tcatgggctt ggaaaaaagc tagttcctaa tatgaaccaa attcttgata
     7141 tgaataaatc attaaatgaa ggtgctatat tgctttcagg gtttggagtg ggttcttggc
     7201 attggaatat attcgctgaa tcaggatttt ttgatattaa taagaggata tgtgattatt
     7261 cagaagtaga attggaaaag tttttgcatg gtaaagcaga aaagattaag atagaaaatg
     7321 ctggtcaaac taacatgaca tatgagggat taatggttaa atttaatcgc ctatacttaa
     7381 gtagagaggg agaaatatct gaagctacta agaaaaaatt gagtaaactt cttatagaag
     7441 atagatgtcc tatatgtgat ggaagaagac ttaatgaaag agtatatagg tctttaatta
     7501 atggttataa tatagcagat ttaactagta tgcaaattga tgaattggct gaagttatta
     7561 aaagtataga tgagccagaa gcacaacctt taattaaagg aataatagaa aagttaaaca
     7621 gtatcataga tataggtctt ggatatttaa cactggatag agagacatct tctctatcag
     7681 gaggggaatc tcagcgtata aagatggtta agtatttaaa tagtaatctt gttgatttaa
     7741 tgtatatttt tgatgaacca agtgtaggac ttcatccaaa agatgtgtat aaattaaata
     7801 atcttttaaa aaaattgcgt gataaaggga atacaattat agttgttgaa catgacccag
     7861 atgttattaa gattgcagac catattgtag atgtaggacc aaaggcaggt aagtatggtg
     7921 gagaagttgt gtatgaaggc agttatgaaa atctacttac aagtggtact ttgacaggga
     7981 atgctttaag taaatttctt cctattaaag aaagtgtaag agaacatagt ggatatttag
     8041 aagttaaaaa ttgtaataaa aacaatttaa aaaatgtatc gattaagata cctaaaggtg
     8101 tattgactct agttactgga gtagcaggag caggtaaaag tacgttgatt aaggatgaat
     8161 ttttaaagca aaatcctagt gctgtactta tagaccaaag ccctgtttca gcaaattcaa
     8221 ggtcgagttt ggcaacatat agtggaatta tgaacaacat aagaagcata ttttcaaaaa
     8281 caaatggcgt aaatgcttct ttattcagtt caaattcaga aggagcttgt gataactgta
     8341 agggttctgg aatagtagaa atgaatcttg cttttatgga gagtataaag agtacctgca
     8401 atgtttgtga aggtaaaaaa tttaaaaaag aagttttaga atataggttt caagggaaga
     8461 atataattga agttcttgaa atgtctgttt tagaggcaat tgagtttttt aatttaaaac
     8521 agattaaaac gaaattacaa tgtattgaaa aaatgggtat tggatacctt actttaggac
     8581 aaactcttga tactttgtct ggaggagagt gtcaaagatt aaagcttgct agtgaattaa
     8641 ataaggaaag ttcagtgtat atattagatg aaccaacaac aggtcttcat atggctgata
     8701 ttgagaattt tataagtata attgaagaga ttgtagataa tggaaatacg gtcataataa
     8761 ttgaacacaa tatagatgta attaaaagag ctgattggat tattgagctg ggacctgaag
     8821 gaggaacaaa aggcgggaga gtaatatttg aaggtattcc aaaacaatta tgtaacaata
     8881 aaatatcatt aacagcaaaa tatatagtat aataaataaa atataataaa attataatga
     8941 tattttaata aatataatgg gtatataaaa tgataattaa acttaacagt aataaataat
     9001 gtgagaaata ttcaaattta attaaataaa gtgtcagaaa tttgtttaaa ttttagtatt
     9061 ttaacggttc tgaccttttt tcttattttt atggagaata tcgaggatgg agtctctaat
     9121 agttactttt ttgtgtctac ttgcaagttt gattaaaaaa tggctataca cacttgtgac
     9181 ttcagtcatg ggaggttcag attataatct taatatataa tttgtgaaat aatttgatga
     9241 cgatttgctg atgtataaac aataaagatt aactacatta aaatttaaat cttgttaagt
     9301 aaaacttata aaaggagaga gatggatgat aaatgatatt ctaaccttat tatctgaaag
     9361 aagtgatttt tttataaagc tatccataga acatttgatg atttctatta tttctataat
     9421 aattgcgatt gttttgggtg gtataattgg tattattgta agtgaatttc ataattcttc
     9481 taaacctata ttgggaacta tcaattttct atacaccatt ccatctattt ctatgctagg
     9541 atttctgata ccattttccg gaattggaaa tactactgct gttattgcac ttaccattta
     9601 tgcattattg ccaatggtta gaaatacata tactggaatt actaatgtgg ataaaaatat
     9661 tcttgaagca gctaggggaa tgggaagtac agattttcag atattgtata aaataaaact
     9721 tccgttagcc ctacctgtta ttatgtctgg tattagaaat atggtgatta tgacaattgc
     9781 attagctggt atcgcttcat ttataggtgc tggaggtcta ggtgtagcca tatatagagg
     9841 aatcacgaca aataacacaa taatgacaat tactggaagt atacttattg ctctattagc
     9901 tttaatattt gattttattt tagggctggt agaaaaattt tttcaacgaa aaagaaaaaa
     9961 gaaaaatagg aaaaaagttt ttgccattct aggaagcctt attcttatag caactatctt
    10021 tacgtcttat ttatttaatc cttcaaagac tcaaactatt catattgcta ctaaacctat
    10081 gactgaacaa tatattcttg gtgagatgtt ggatatttta attgaaaaaa acacaggtct
    10141 aaacgtggaa attacacaag gtgtaggagg gggaacatct aatatccagc cagctatgga
    10201 gaatggagaa tttgacattt atccagagta tacaggtaca ggctggaata tggtacttaa
    10261 gaaaaatgaa ttatatactg aaagtatgtt tagtaaacta cagtcggaat acaaaactaa
    10321 acttaaaatg caatggactg gtatgtatgg tttttctaat agctatgcat tagcagttag
    10381 aaaagaagtt gcagataaat acaatttaaa aaatataacg gacttaaaag atgtatcttc
    10441 taaattgaca tttggagctg aatatgactt ttatgagaga gaggatggat atactccatt
    10501 gtgtaataca tatggactga actttaaaga tacagttgat ttagatattg gattaaaata
    10561 ccaagctatc aatgaaggta agattgacgt aatgcctata tttacaactg atggtcagta
    10621 tagtgtttca gatgttgtag ttctaaaaga tgataaaaat ttctacccat cttatcaatg
    10681 tggaaatgtt gttcgtttgg aagtattaga ggaaaatcca gaactatcaa aggtatttaa
    10741 gatggttgga gatattttga ctgataaaga aatggctaaa atgaattatg acgtagaaaa
    10801 caacaattta gaacctagag aagttgctcg tgagtttctg aataagaaag gtcttttata
    10861 aattggagga aatataatga cacctattat acaatttaaa aatattaaaa aacaatataa
    10921 tgataaaact ataatagata atcttaattt agatatagaa aaaggagagt ttttgactgt
    10981 aattggttcg tctggttctg gtaagacaac actcttaaaa atgattaatg gtctgatttt
    11041 gccagatgga ggaaatattt tgataaacca aacagatatc aaaaacgagg acttaattaa
    11101 attaagaaga agaataggat attgtgtaca gggaagtgtt ctttttcctc atatgactgt
    11161 tgaagaaaat atttcatatg taccaaatct cctaagtaaa aagaataaat tagaagtaaa
    11221 aagtgctgta aacaagtgga tggaaatagt gggattgcca aatgatatga aagtgcgtta
    11281 cccatcagaa ttgtcaggtg gtcagcaaca acgtgtaggg attgcaagag ctttagcttc
    11341 ttctccagaa attttattaa tggatgaacc ttttggtgca gttgatgaga ttacacgaaa
    11401 gcaattacaa aaagagataa aagaaattca taaaaaaaca ggagttacaa ttatctttat
    11461 tacgcatgat atttatgaag ctttgatttt gggaacaaag actttggtat taaatcatgg
    11521 agttgttcaa cagtatgata ctcctgagaa tattttaaat actcctgcta accaatttgt
    11581 agaccagtta ttgaatataa gaaaatctat aatagatgat gataatttaa aagaataaat
    11641 ttaaatttaa aatcaaattg ttgtgataaa aactattgat ttagagctaa cttcaagttg
    11701 tatacttgaa gtggaaaagt tagattaagg tatagaaggg catttagcag ttggctgtag
    11761 acgaggtaac tgctgaaggt gctttcaata aatggctaga acctgtatct gttgaagatt
    11821 ataataaatt gaaataagaa gctcaatata cagagtagat aggcacttca aatagaagtg
    11881 tcttttgtgt gccataaaat aaatcaaaat attagcaaag aatgtgaaaa acaaaataaa
    11941 ataatatgct atctttaaaa taggagggat gctatatgga taacaatttg attaccattg
    12001 aaaaaacttt agattatata gaaaaacatc ttttagatga gatgttagat ttaaatgtaa
    12061 tttctaaaga gataggctat tcaaaatacc atttacatag aatgtttaca tcagttgtcg
    12121 gatttagtgt acataattat atacaaagac gtagacttac tgaagcagcg agaatgctaa
    12181 tttttacaga aaaaccaatt attgagattg ctttaatctc ggggtatgat acacaacgct
    12241 ctttttcaag agggtttaaa aaaatgttta aacgtagtcc taattttttt agaagacatc
    12301 aagatttttt accactacaa ttaaaatttg atattcataa tagaaaaaaa ttacgtggag
    12361 atatggtttt agatgttaaa aaagttaatt gtgcagatat aaatattgtt ggctattctg
    12421 gtaaagtaag aaaaggattt catattattg gaaaatgctg gagggatttg cataaaaata
    12481 aagagatgat agaaaataag gtagatttag gttttttaat tggagttagt gattatagca
    12541 attttaaaga gattgagaat actcctacat ttacatacat tgcaggtgct caagtagcta
    12601 cttttggcaa attacctaat ggaatggaaa aattcgtatt accgaaaagt aattatattg
    12661 tttttacttt tattgggaaa aatgaggata gtatgcaaaa tgttgtagaa tatatctatc
    12721 aagaatggtt ccctaattca agttgccagt ttaatgaaaa taatttatat gactttgtaa
    12781 aatatggaga aaaaactgat gagaatggtt tgagtgaaat tcagttttgg gttccaatca
    12841 tttaaaagaa ggtattatgt ataaagtaga tggatttata taggcaaagt tttacagcag
    12901 tatgtattta taaataattt atagtttgta ggaaagaaat aattttacta taagattatg
    12961 ataaaataca caatactatg acaaaatagt gttaaataat agatttaatt ttgcatagga
    13021 aaagttctat aatggtgtgt attcataaat aatttataat ctgtaggaaa gaaatagttt
    13081 tactataaga ttatgataaa atacacaata ctatgataaa atagtactaa ataatagatt
    13141 taattttgca aaggataagg tgttttaata aaaatgaatg tagaaaacga attacttaaa
    13201 aacctagata gattgcatac aacagagtta ggcgttgtaa gaattaagaa aaatctttct
    13261 ttggagacaa atgatgtagt gaactggtgt aaaactaaaa tagaatctcc aaatgccatt
    13321 attaatagaa agggaaaaaa ctggtatata agtgtatatg attgtattat aacagtaaac
    13381 gctcacagtt atacaattat tacagctcat aaagaaaaga aatgaattgc aaaatacaaa
    13441 ggtcaaaagc attttccact gtttgtagta cctatgaaga agtatataaa ataatattac
    13501 ttttgaataa taatttaaat tttggaggtt gaaaaaatga atgatactgt aaaagaaaaa
    13561 ttggcagagt cactaacttc tgatactact gatattttac cttatttgcc ttatttatta
    13621 caagattttt gggaattagg aagttcacca gaacaaatgt tacaattatt tagaaagcat
    13681 atacctttta atgaggatac aaaagttttg gatttagctt gtggaaaagg tgctgtatct
    13741 gtgaagcttg caaaagagtt gaatatacat atcaaaggta ttgatttgat acctgaattt
    13801 attgattatg ctagaagaaa ggctattgaa tataaggttg atgctttgtg tgattttgaa
    13861 atgaatgatg ctaatagttc tgtaaaaatt gagcatgatt atgattgtgt gatttttgga
    13921 gctgtagggg atattttagg taattataaa gaaactataa gtaagctatt acctacaata
    13981 aaaagtaagg ggttcatttt aattgatgat gcatatgtag tagataaatc tacaaatgaa
    14041 cagcttaatt ttgagagggt gtatcccact tacaatgagt ggtgtatatt gttcaaagaa
    14101 ttaggtctga agctaattga atgtatacca tgtttagaac ttgaaaatga tgttgaagag
    14161 gaaatgaatt ggattataac tcgtgcaaat gagctaatta aaaaatatcc ttctcaaaaa
    14221 gatatgtttg aacaatatgt tattagccaa aaaaatgaat atactgattt acagcaggac
    14281 cttgttggag caacttggat tttacaaaaa gaataagata aatattagac tagataatca
    14341 atgttatagt gaattatccc atgtctagtg aatataaata acataaaaaa ccgtcaagat
    14401 gaatagttta ttcgtgcttg acggttttta gtatttgttg aagtaaaatt ttatttcttt
    14461 agtatatcac ttttagtcaa tccatttgat ttagcttgag tattccattg atgattcccc
    14521 ataagtttat ataggaatct agggaagtta ggtgaaataa aaatagtact tttgttggaa
    14581 tcatctatat gtatattatc actaagtata ttttttgaaa gttcttttaa tgcaattcct
    14641 aaatcttttt taggtccttt acccaaaggt acggattcta gtgaaccaaa catctcccca
    14701 gctccaattc caataccttg aacccatgta aagttgattt ttttacacca atgctctatc
    14761 atttgaattg ccaaatgatt atgttcacct tcattgaatc cacagttaac tattgcatac
    14821 actggaatag gttttttatt ttgtgttttt aaaaattttt cacatttctc taaaaaatga
    14881 agtaaatgag atggaatacc atctacataa agaggagatg cgattattaa tctatcacaa
    14941 ttaagtatgg cattaagagc gtcaggatac ttagatgtgt tatctacttt aaatgtaaaa
    15001 actttattat cattttgaat aagttgtttt aattcagata aaaaatactg tgaattattt
    15061 ttatttactt ttggactacc atttatcatt actatattca tatggattca cctcttatat
    15121 cttgtatatt ttcatagaaa caaacagagt gttcttttat attgaaattt atagcatttc
    15181 catttactaa tttcgtagca gtttcttttt cagcttctgt aatacaatct ccatagaata
    15241 tagcttttaa atttatctgt ttatcatatc tgcttttatg acgcatcata ttatctttta
    15301 ttacaaagta tggaagaata taattaatgc ttttatcaag tacgtttttg acaaaagggc
    15361 taaaccctcc gtaacagcat ctgcttatta taataattcc atcagagtca tttataagtt
    15421 tacccatgtt gctgtaataa tcttttacaa cacattcaga aggagtttta atccagcaac
    15481 caaaacaacc aatacatttg tggatttctt ttgtgtttgg aagtattttt atattgtcat
    15541 caagtttggg taataacttt tctaattctt tgtcagttaa atcatgtatt aaaagcctca
    15601 taaagtccat ctccttttat tatgtatgtt tacttctaaa aattatatct tatagatttt
    15661 tcagtaaatc tttacaccaa ttaataacaa aattataata gtcaactcca taaatcattg
    15721 ttgcatacat atatgtatat tggtcaacac aatgattttc ttctgcatca tttttttgtt
    15781 tacttaattt atttagaagt aattctactt cagttattaa catttttaag tttgtttcaa
    15841 ttatttcttt gggtagatac ttgtaaaaga atatattaac aaggtggtct tgctttgttt
    15901 tagaaaaatt tataggtttc tttaaccatt caagaaatac ttctttacca gtattagtta
    15961 tggaatatag tttttttaat ttgttaccat ctataacttc gtgatagtgt atatatcctt
    16021 ttgtttctaa tcttttaagt gcaggataga tacttccaaa gctggcgtca aaaaagtacg
    16081 aggtactttc tgacattatt tgttttaagt cgtatccact taattctttt tccattaaaa
    16141 atcctaaaat aatgtattct aacatattac ctcctggtat caattagata tatatcgatt
    16201 cgatatattt attattacag ataataaatc ttacgtcaag atgcttttta agataagcta
    16261 aaaagaatta ggagttattg ataaatatgc aaaaaaatta atataaaagg taattaaata
    16321 tcaataaaga tttaaaaata gttaaatcaa agtaagagtc taatatataa aatttatagt
    16381 aactttatgg tttaaatata aacttgtgtg ctattgacaa agtataaaat tagcagtaga
    16441 ataattgcat gagcaaatag attgttgcga acgcaaaaaa aggacaatag atattaaagg
    16501 agagaatatg agagagctat taaaatgggt ttccattata aatagataca atacaaatta
    16561 tattgacagg aaattggcgg atattggaat caataatagc caatattttt atgtattaca
    16621 catatgtaat aatccaggta ttacacagga cactatattt gagaaaattc ttgtgaatcc
    16681 tagtaatata acaagagctt tggcaaattt agaaaaagaa ggctttataa caagagaacc
    16741 aggtgtaaag gataaaagaa catggcattt atatcctaca gaaaaatctt taggatgtta
    16801 tgatgaaata ctaaaaataa caaatgggta tgttgaggag ttgttgagtt catttgagaa
    16861 agaagagcaa gagttgttta tgtcaatgtt aaagaaagtt gcatttttgg ctattgatat
    16921 gaatgaagaa gcaaaattgg aggcgaagga aaatggaaga aaaatataag gagccattgg
    16981 aatatgaaaa ggtttcaaag ttattaacta agtacgcaat tcctagtatt atagcaatgt
    17041 tagtaagtgc tttatataac attgttgacc aaatatttat tgggcaaggt gttggtgtat
    17101 tgggcaatgc tgctacaaat gtcacttttc cactaacaac aatatgtact gcaattgcat
    17161 tattgttagg aattggagga gcgtctaagt gttcattgga attaggtgct aaaaattcag
    17221 aaaaagctac aaaagcagca ggaaattcta tatgcttgat ggctgttttt ggaataagtt
    17281 tatttatagt agtatcaata tttttaacac cactattaaa attctttggc tctacatcag
    17341 aaatactacc ttatgcacac acatatacaa aaattacatc aattggatta ccatttctta
    17401 taatgtccac tggaatgagt aagttgatac ttgcagatgg gagaccgaaa gcttctatgt
    17461 tttgtatgtt aataggagca gttattaata caattttgaa tccattattc atttttgttt
    17521 ttaatatggg aattgctggg tctgctttag caactgttat tgggcaactt atatcttttg
    17581 gaataagtgt tcattatata aagaattttc aacatattaa attacataag aaaagtttta
    17641 aattagatag tataatttat aaacatatat ttgcgctagg ttcaagctca tgttttaatc
    17701 aattagcaat gactgtaaca cagatagtta tgaataatac attggcatat tatggggcta
    17761 ggtcagttta tggaagtgag attccacttg cttgtgtcgg tatcattatt aaagtaaata
    17821 tgatttttat atctataatt attggtatat cacaaggtat gcaaccaatt atagggtata
    17881 attatggggc tgaaaagtat aatcgtgtaa aagaagcata taagtttgca gtgggaagtg
    17941 caactattat atctgttatt gcattcttat gtttccaatt attcccaaga caaattacgt
    18001 ctatatttgg taacggaaat gagacttatt ttatatttgc agaacattat tttagaactt
    18061 tcttgttctt aacatttata aatggtgttc aaatagtatc atcaactttc tttacatcaa
    18121 ttgggaaatc agtgttggga ctttttactt ctttgactcg tcaaatttta tttttaattc
    18181 cattgatagt aattttacca atgtttatgg gaattgatgg agtaatgttt gcaggaccaa
    18241 tagcagatgc agcagcggca atggtatgta tatactttgc agttcatgaa atgaaatcat
    18301 tgactataaa gcaaaataat ttgatgagta accataataa gattgcagag gtataagaca
    18361 atatttaaga agtatagaaa attaatttaa agaagtataa taaactaatt taggaagtat
    18421 agaaaattaa tctaaagaag tataataaac taatttagaa agtatagaaa attaatctaa
    18481 agaagtgtaa taaactaatt taggaagtat agaaaattaa tctaaagaag tgtaataaac
    18541 taatttagga agtatagaaa attaatttaa agaagtataa taaactaatt taggaagtat
    18601 agaaaattaa tttaaagaag tataataaac taattcagga agtatagaaa gctaatctaa
    18661 agaagtatag taaactaatt taggaagtat agaaaattaa tctaaagaag tataataaac
    18721 taatttaaga aatatagaaa attaatttaa agaaatacaa tacattaatt tttaagtaac
    18781 attaaattaa tgtaagtaaa ataatgttca tatgaagatt taaaggtgca ttttctgaag
    18841 ctaagtatat gttgtagagt gttaggtctc tctatcctgt gaagtttaat agctcaagaa
    18901 aatgcactat ttatgatgat tattttgttt tatttccaat tttggaaata actattctaa
    18961 ttaaatctaa aattatacca taaataagaa aagaaagtat agatgctatg taccaataaa
    19021 tcgaaattga ccctgtaatt gttctacatg ggatttgcat acctgaatcc ataaaaacaa
    19081 aaaaactatc aactctggaa ataatagaca aaataggatt taaacctatt agaacaatac
    19141 tttttgagtc ttgaccaatt tgatgcatat aaatctcaaa taatgcaatt aaaaaaaacc
    19201 aaaatgtaaa agatttaata atttttttca tcaaaatacc tcacataata taaattctgt
    19261 ttgcactatt tgcttactac aactatttat ctccattcag tcacatcact taattgtaat
    19321 ctaggtcttc ttgatggttc ttcatcagga taacccaaag atattgctgc cactaattga
    19381 ctatctgtat ttaaccattc acataattca cgatatgcaa agtatacatc acaaatccaa
    19441 agactaccta gacctaattc cacagctgta agcgacatat tctgaattgc agctccaatt
    19501 gattgcatgt ttgccatttc atagaatcgt tcttcagggg atagcttttc taaaggtgat
    19561 ttacctaata tatttaaaat aaaaattgtt actggagctt gtttcatgat ttcaactgtg
    19621 taatttgcac cagcgatatg ttgacgactt cctggaagaa gcccattatc attaatttca
    19681 ttttgaatac ctttgctcat ggctttaagc atagattctt tttccttttc agtgatgaca
    19741 acaaaacgcc atggttgcct gtttttagat gaaggtgcat ttattccagc ttcaattatt
    19801 ttctctatag tttcatgtga aatgctttga tttttatatt ttctgatact tcgtcttttt
    19861 gatatagaat cacttatcat tttaagtaac ctccgtttat tttttggaaa aatctattta
    19921 atttttattt tctattttaa ttattttagc attaatcaga aaaaaagtca ttgattttag
    19981 tatacaatta ttaatgatta tattaagaat tgtatcaaaa agtatgtgat tatactaagg
    20041 gattatatta aacattatat ttaaaattgt atgaaaggtt gtatttaata ttatattgag
    20101 agatata
//
LOCUS       DAMJVG010000071        20079 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.071, whole genome shotgun sequence.
ACCESSION   DAMJVG010000071 DAMJVG010000000
VERSION     DAMJVG010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20079)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20079)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20079
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.071"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(37..1269)
                     /locus_tag="PC512_002797"
     CDS             complement(37..1269)
                     /locus_tag="PC512_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2442530.1"
                     /translation="MINKNVFTSTKNHLIKMYIIVVGSFLIIFSIFIYSYFRGLTYSG
                     IDSEINDELEYIVSQFKRTSFLNPIRLKDPKDMVYVYEDGRISYYTQNEYFDELLPDR
                     RLDKKNSFFKYTENGYTFRELNVDVGRYQIQIIRNIDSEMNSLRQLTSVLIIGILISV
                     IITYFVAVYLTRKALIPIETAWKNQAKFIQDASHELRTPITIVSSKLESMLKSPESTV
                     NDEVETIATAMKETRRLKKMITDLLSLTKEDSIVKVNLEEIDLEKLLEEISEDYIDIA
                     EFQEKRFVFNSKLKNKVIITDKNKLRQLILIFIDNAFKYTKLGDEIALELKEDIEDEV
                     TLLISDTGIGIKKEEIPLIFDRFFRSENVRNKDLEGSGIGLSIARMISLNLSIDINVT
                     SDVDIGTTFELSIPKKLK"
     gene            complement(1259..1930)
                     /locus_tag="PC512_002798"
     CDS             complement(1259..1930)
                     /locus_tag="PC512_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2442531.1"
                     /translation="MKVLIVEDNKILLESVVEELSKHFETEKCEDGEEALYLVNQNIY
                     DLVILDLMLPNINGFDILKKMRVNNIDTPVLILTAKETLDDKVEAFTIGANDYLTKPF
                     YMEELVARVYAILRTNGKIKERNGLEFKSLYLDTLEKRVYIEKEEIKLQNKQFNLLEY
                     FVLNKGSILLKEQIYDRIWGIDSDATIEIVEVYVSNLRKKLSKYGYDKYIKTKRKVGY
                     IFDDK"
     gene            complement(1946..2782)
                     /locus_tag="PC512_002799"
     CDS             complement(1946..2782)
                     /locus_tag="PC512_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442532.1"
                     /translation="MNKIVKKSISLMIILTIFIFMLTACEKDEQPDSVDIQTEDKNEI
                     KIDEGNAKVLNIGKSEIINIDEGDKVDTSTKVENNSTFNISNVELIYNEYDENKKIIS
                     SDSKALLDMTLMPGKVAYIECGHKTFVKGVEVYAYEYEAEGKIVYVNLKENTINIRNN
                     NIKLENSSQYEVLSTSELKKVNESNEGITYQVKVKNSSSKDLGNIILKTAEVNENGEY
                     LTVNRVPSYKILKPSEETDIDILCSTKAKSVEIVGYTYDDIKEKANVDIDLKSHKVKI
                     DK"
     gene            complement(2808..3482)
                     /locus_tag="PC512_002800"
     CDS             complement(2808..3482)
                     /locus_tag="PC512_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDF2442533.1"
                     /translation="MNNNEDRIDKFLELQSKGFKFAEIAQNLKISQSTLRTFLNKKGY
                     KSEKGKYIFKDELNYNKSLDNRNLEEEKAKEYEKSKKNTISNRKKVSTKKKISNEKAL
                     SKSVEQIEFNDTGLKNAKPKQNIKPKKDRKINITQEDLDKLCEVYDWYLEVKDYNIKP
                     KKVSNKKDVHIDDEHIDELKTTRIRIDKEIWNDFERLCSNSNFEKHQILTQALKEFMK
                     KYKNLL"
     gene            complement(3496..4224)
                     /locus_tag="PC512_002801"
     CDS             complement(3496..4224)
                     /locus_tag="PC512_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HDF2442534.1"
                     /translation="MMFDRVKWNKLDYNELLEYMMSIQDIKYRDFNKKLIPGTENIIG
                     IRVPNLRKLSKEISQGNWKEFLEVAEDTYYEEVRLQGMVIGNINSNFEETLYYVKRFI
                     PKIDNWSVCDGFCSDLKSMKKYKENMYDILKKYVYSKNPWEIRFALVMFLIYYVDDKH
                     IKEIFEYCNNIQSEEYYVKMGMAWLLSICFIKCEEETFLYIKNNNLDDFTYNKMLQKI
                     IESNRVDLEKKNIIRSMKRKTRRC"
     gene            complement(4351..5040)
                     /locus_tag="PC512_002802"
     CDS             complement(4351..5040)
                     /locus_tag="PC512_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF2442535.1"
                     /translation="MDRYSEITNKNQREIVLLKGFPCIWGKCSFCDYIDDNSNLEEEM
                     NKLNLKVLKNVTGKYGVLEVINSGSCFELPKDTLEKIKCIIKEKNIKKLFLESHWSYK
                     NRLKEMREYFEIPVVFKIGVETFDNDFRNNILNKNANFKTPQDVKEYFDSPCIMVGIK
                     GQTKEMIDKDIEIILNTFEKATVNVFINNSSSIKRDEELVKWFVSKYKFLDENPNIEV
                     LYNNTDFGVGD"
     gene            complement(5048..5611)
                     /locus_tag="PC512_002803"
     CDS             complement(5048..5611)
                     /locus_tag="PC512_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDF2442536.1"
                     /translation="MKRKICVKTITLIAFGISINIIGAFIAMGLRLPVYLDSIGTIMI
                     ASLLGPKYAVVTGVFGSLISGITFDVYSLYFAPVQISTGLLAGIAFKKNFLRGLKTPL
                     GVLLFAIPTSIISSIISAFLFGGMTSSGSSYIVQILKVLGLGDVFSVFVTQVFTDYGD
                     KLLAVVLVNLGLNAVPKTLKVSLTGGK"
     gene            complement(5613..6581)
                     /locus_tag="PC512_002804"
     CDS             complement(5613..6581)
                     /locus_tag="PC512_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HDF2442537.1"
                     /translation="MEKRKVIIDCDPGIDDSLAILLALNSPELEVIGITTCCGNVPAN
                     IGAENALKTLQMCSSLNIPVYIGEEAPLKRKLVTAQDTHGEDGIGENFYQKVVGAKAK
                     NGAVDFIINTLYNHEKVSIIALAPLTNIAKALIKDKKAFENLDEFVSMGGAFRIHGNC
                     SPVAEFNYWVDPHGADYVYKNLSKKIHMVGLDVTRKIVLTPNIIEFINRLDKKMAKYI
                     TEITRFYIDFHWEQEGIIGCVINDPLAVAYFIDRSICKGFESYVEVVEDGIAMGQSIV
                     DSFNFYKKNPNAIVLNEVDEKKFMYMFLKRLFKGYEDIIDSVEGVI"
     regulatory      complement(6682..6725)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            7090..7719
                     /locus_tag="PC512_002805"
     CDS             7090..7719
                     /locus_tag="PC512_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2442538.1"
                     /translation="MSIKERRKNEKEEMKKKIMDASIEIINQHGYENLSIRKIATKIE
                     YSPTTIYLYYKDKAEIISDMTNKLYNTVESNAIDIMNNCSSLPIDKQIIEIMTSFIKT
                     LSSEPEMAKSIMYSRMNIIFASENTNNTPSNNGIKMLDKFLSIGIEQGIFKKNIDKSS
                     WMLISALLGFVLCVVENKLYSLHNFSQLIENFLDILVGGLYNENSQQGY"
     gene            7694..8098
                     /locus_tag="PC512_002806"
     CDS             7694..8098
                     /locus_tag="PC512_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HDF2442539.1"
                     /translation="MKIRNKATNKKKKYVKISIALFFVFICIIIVIVSNLKPENLVVK
                     DIDINNVKNGIYTGSADNNLVKATVSVEVNNGKIQNINILKHDHLLGKPAEKITTSII
                     KQQSLDVDAITSATYSSNTIRKAVENALRKGE"
     gene            8101..8574
                     /locus_tag="PC512_002807"
     CDS             8101..8574
                     /locus_tag="PC512_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HDF2442540.1"
                     /translation="MNTIIIYSSKYGCTKDCANILKNKLSDNVTIVDINNNNKIELSK
                     FDKIIIGSSIYVGSVSKKIQVLCNDNVELLNKKQVGIFLCCGFSEQADKYLKSNFPSS
                     LLESANAIGIFGSEARLEKMKFLDKLIMKAVSKGNYDSFRISQDNIDNFLINLNS"
     gene            9144..9809
                     /locus_tag="PC512_002808"
     CDS             9144..9809
                     /locus_tag="PC512_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HDF2442541.1"
                     /translation="MIKLIGILIVVIGFILKIDTLFTVLLAGVATGIVAGLDFNQIFT
                     ILGDSFVSNRGVSLFILTLPVIGVLERYGLKQRAVSLIEKLKRLTTGKVLTIYMIARQ
                     IAGALSIRMSGHPQFVRPLVNPMAQAAGLSNSDELKESDEEAIKALSAASENYGNFYG
                     QNLFAGSSGVLLIASTLTQFGYNVTGLNIVKASTIMAVIALVVATIQFTLYDKKLNKS
                     HKK"
     gene            9831..10763
                     /locus_tag="PC512_002809"
     CDS             9831..10763
                     /locus_tag="PC512_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HDF2442542.1"
                     /translation="MQNFINISLEIFYALMGFLMIVIAYKSFTTINNNKKYGTSLFWI
                     LISLPFIFGRLIPANIIGIILILSSLLTLSKQVVFAKYEEPDENFGKEQADKLKNKIF
                     IPSLILAFAAVVVAMSLSNFDNSSQFAIGVGSIIALISALIITKAKPATSVQDGSRLL
                     QQMGPASMLPQLLVALGALFTQAGVGEVISTMISGVVPADSRLFGVIAYVLGMVIFTM
                     IMGNAFAAFSVITAGIGIPFVLSQGGNPAIIGALALTAGYCGTLLTPMAANFNIVPAA
                     LLECKNDYIVIKYQAPVALVLIIAHILVMYFLGF"
     gene            10784..11425
                     /gene="pcp"
                     /locus_tag="PC512_002810"
     CDS             10784..11425
                     /gene="pcp"
                     /locus_tag="PC512_002810"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HDF2442543.1"
                     /translation="MKILLTGFDPFGGEPINPAQEAVERVNNNINGAEIIKITIPTVM
                     TKSVEAIDKAIQEHNPDIVISVGQAGGRFDITPERVAINIDDFRIKDNEGNQVIDTII
                     KEDGEPAYFSKLPVKAMVKHMNENKIPASVSNTAGTFVCNHVMYGILYMIDKKYPNIR
                     GGFIHIPYTTSQVIDKKNTPFMSLEEIVKGLELAIEACIIYKEDVKEIGGEIS"
     gene            complement(11545..11877)
                     /locus_tag="PC512_002811"
     CDS             complement(11545..11877)
                     /locus_tag="PC512_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2442544.1"
                     /translation="MSIDCISNTDLSETGFSYTLSLISGKYKMIILYCLVEFEVVRYN
                     ALKRYINTISYKTLSLSLKELEADNLIIRTEYPQIPPKVEYSLSERGKSLIPILDAMC
                     EWGERNRP"
     gene            12143..12763
                     /locus_tag="PC512_002812"
     CDS             12143..12763
                     /locus_tag="PC512_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF2442545.1"
                     /translation="MKVLLINGSPNQYGCTYTALNEITKVLSKHDIKTEILYLGKETI
                     PGCISCASCFETGKCIRNDKVNKLIEDLDNIDGIIIGSPVYFSSATGQLTSFLDRLFF
                     IAGSRMATKLGASVVSCRRGGASATFDQLNKYFSISNMPIVSSQYWNQVHGFTPEDVM
                     KDEEGLQTMRTLGENMAWLLKCISAGKKAGIKEPQYEETIMTNFIK"
     gene            complement(13088..13912)
                     /locus_tag="PC512_002813"
     CDS             complement(13088..13912)
                     /locus_tag="PC512_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraX"
                     /protein_id="HDF2442546.1"
                     /translation="MDFFKKGISGFTIKILALIFMTFDHIAAFMPQTMQIPIWFHWVG
                     RISAPLFIFMAVEGFYHTSNRKKYISRLYIWSVIMAIGNQIINNVFSHPEGAIIINNI
                     FSTLFLIAIYLQAIEFIKKFRKEKEIKYFIIGLLMIIIPIILGIFTVALLFKVTNRVI
                     ALFMILVPVPFLVEGGPIWIILGIIFYLCRGKKFSLSICYVLMCIFIFTTMSNGDYSL
                     KNSILQNYQWMMIASLPLMLLYNGEKGKSMKYLFYLYYPIHVYILYILGIYLINGF"
     gene            complement(13923..15326)
                     /locus_tag="PC512_002814"
     CDS             complement(13923..15326)
                     /locus_tag="PC512_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2442547.1"
                     /translation="MKWKITRNFIFTIVFVAISVVIINIISILYVISTNSFFKVVDSG
                     NNPEEFARSFEKDLYEKDGEFKLSKIGAEKLEKSNSWIQVLNDLGEEVYGVNVPKDTP
                     KKYTPFQMVNNYKYIETKYVNFVLEKYLNKKHLNIIVGIPSRDISRIILTYSQNNIKK
                     TLNKVIIITLVIDSVVALGVGYLFSRKLTKPISSVLWSIETMANGNYSLYLKDRGIYE
                     EVFKNINMLADTLRVNEVERKENEELREEWLANITHDIKTPLASIQGYAEIINDKDYE
                     FEEDEIQEYTEIIYNKSKYIKDLVDDLNLSTRLKNNTIVLDKKKINLVSLVRDIIIDI
                     LNDNRYKNRNIEFESNEDLIEVYVDSILFRRAITNLIFNSIVHNSEGTLISVEIVKKD
                     NIEIIIKDNGIGISKSDLKHIFKKYYRGTNTGEMHKGSGLGMAISKEIIEIHKGKIYV
                     SSEIGIGTKIIIEIKQN"
     gene            complement(15330..16055)
                     /locus_tag="PC512_002815"
     CDS             complement(15330..16055)
                     /locus_tag="PC512_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012450879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2442548.1"
                     /translation="MENRVLIIDDEVEILKLLETVLKKEGLNNIYTAKTKKEGLELFK
                     SINPDLIVLDIMLPDGEGYDICKEIRKTSNSPIIFLSAKTEELDKLLGLAIGGDDYVT
                     KPFSPKEVAFRVKAHLRRLSYFSDAQNESKNLNNNEEKIISFGPYILNESRAELIKDG
                     KSIGLFAKELKILSLFAHNQNQIISKEKLWDKVWGEDYVGFDNTIMVHIRKIREKLED
                     NPSKPEYILTIKGLGYKLAVKED"
     gene            complement(16167..16940)
                     /locus_tag="PC512_002816"
     CDS             complement(16167..16940)
                     /locus_tag="PC512_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2442549.1"
                     /translation="MMYLVKAEMIKILKSKSVWIIWLFLIFFGFFLIRKFDVLDTYAD
                     IFYKIEGSIPLIGLIMFIITSGNYIKEYDSNMTGLINTTKKGKKSVVLSKLVANGLIL
                     SIINISFILLVGIRGFSFFDFKNLNESIHNLWYFGNSNLNLTVIQMYIIVILTTIFAS
                     FIFAQIGLTLSSIFKSAVIPFILGGLIMAIPYFSVGFIPDKAIKFMSVTPNWIMMSQQ
                     MVKYNVPSILIVFSIVISIILMIVLTKITYENFTSSKRF"
     gene            complement(16946..17833)
                     /locus_tag="PC512_002817"
     CDS             complement(16946..17833)
                     /locus_tag="PC512_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2442550.1"
                     /translation="MNKLEIENLSKIYGKKVANDKITVTLENGVYGLLGPNGAGKSTL
                     MKQITTLIKPDEGQILYNGEDIFKMDADYRNILGYLPQEFGVYKNFTAKEFLQYIGAL
                     KGLRGKYLNSKIGELLDLVGLYDVRNKSIGKFSGGMKRRAGIAQVLLNDPKIIVLDEP
                     TAGLDPQERARFRNLIAKMSRDKIIILSTHIISDIESVAKETIMIKDGKLLMKGTHKD
                     ILSHMENKVYNVQVKNECEVDDIQSKYKVVSIQSDINSIVLRIVSEDIPSEDNIQPVQ
                     AKFEDVYMFYFDLEDAREV"
     gene            complement(17847..18869)
                     /locus_tag="PC512_002818"
     CDS             complement(17847..18869)
                     /locus_tag="PC512_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442551.1"
                     /translation="MVNWEIKKLAKSKSMFISLGILVLILMISIFITPVLETESYYID
                     KEKGRIEDTRSGIDIGNEKFQNKINVLKQFSNQTDTGEFSKKIELMSKKKLDNLSVNE
                     YKDISFWKVFNYRVTNSLINVGMLIIISIIISNIYVDEVVTSVKDIILSSKEKKKALN
                     SKIFVALLVPLVIYSVYLMGIFIITCMQQGVPVNGDLESFRIVDNVVALKTNLSITKY
                     VILNIGIELLMFEGWAMIAIFGSFISKSSISSISFFIFIISITKIMSVIHILPKKLLS
                     VVSNVNYYDLIFGFNKIIGNYLGDIMIFKVNIDIVNIAIGLLMAILIGAMSLCFLVIK
                     SDYISR"
     gene            19444..19620
                     /locus_tag="PC512_002819"
     CDS             19444..19620
                     /locus_tag="PC512_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442552.1"
                     /translation="MFIGEIDKCTHILTAYISSSYDYCNFLDTQLDDFISEYGETVVE
                     TCLHQVLLLVSRYN"
BASE COUNT         7032 a         3103 c         2158 g         7786 t
ORIGIN      
        1 attcttcatt tctaaaaaca attttttata tttttattat tttaactttt tgggtattga
       61 caattcaaat gtagttccaa tatctacatc agaagttaca tttatatcaa tagataagtt
      121 taaactaatc atgcgagcta ttgaaagtcc tattccagaa ccttctaaat ctttatttct
      181 tacattttca cttctaaaaa atctatcaaa tataagaggt atctcttctt tttttatgcc
      241 tataccagtg tcacttataa gtaaagttac ctcatcctct atatcttctt tcaattctaa
      301 tgctatctca tcacccaatt ttgtatactt aaaggcatta tcaatgaaaa ttaatataag
      361 ctgtcttaat ttatttttat ctgttattat aactttattc ttaagtttag aattaaacac
      421 gaatcttttt tcctgaaact cagcaatgtc aatatagtct tctgatattt cttccaataa
      481 cttttctaaa tctatttctt ctaaattaac tttaacaata gagtcctctt tagtaagaga
      541 caataaatca gttatcattt ttttaagtct tctagtttcc ttcattgcag tagctattgt
      601 ttcaacttca tcatttactg tactttctgg ggattttaac atactttcta attttgatga
      661 aactattgtt attggtgttc ttaattcatg agaagcatct tgtataaact tagcttgatt
      721 tttccatgct gtttctattg gaattaaagc ttttctagtg agatatacag ccacaaagta
      781 agtaattatt acagaaatta atattccaat tataagaaca gatgtaagct gtcttaaaga
      841 attcatctca gaatctatat ttctaattat ctgtatttgg tatctaccta catctacatt
      901 taattctcta aaagtatatc cattttctgt gtatttaaaa aacgaatttt ttttatctag
      961 tcttctatct ggaagtaact catcaaaata ttcattttga gtatagtaac ttatccttcc
     1021 atcttcatac acatacacca tatctttagg atctttcagt cttattgggt tcaaaaatga
     1081 agttctttta aattgagaga ctatatattc aagttcatca tttatctcac tatcaattcc
     1141 actatatgta agtcccctaa aatatgagta tataaatata gaaaagatta ttaaaaaact
     1201 acctactaca ataatataca tttttattaa atgattttta gtactggtaa atacattctt
     1261 atttatcatc gaatatatat cctaccttac gtttagtttt aatatattta tcatatccat
     1321 atttacttag tttttttctt agattactta catatacttc cactatttca atagtcgcat
     1381 ctgaatcaat tccccatatt ctatcataaa tctgctcttt taataaaatt gaacctttat
     1441 ttaatacaaa atactcaagc aagttaaact gtttgttttg aagttttatt tcttcttttt
     1501 caatatacac tcttttttct agtgtatcta aatataaaga tttaaattct aatccgtttc
     1561 tttcttttat ctttccatta gtccttaata tagcgtatac cctagctact aactcttcca
     1621 tataaaaagg ttttgtcaaa taatcattag ctcctatagt aaatgcttct actttgtcat
     1681 ctaatgtttc ttttgctgtc aatataagta caggtgtatc tatattatta actctcattt
     1741 tctttaggat atcaaatcca tttatattag gaagcattaa gtctaaaatg actaaatcat
     1801 atatattttg atttactaag tataaagctt cttctccatc ttcacacttt tcagtttcaa
     1861 aatgcttgct aagttcttct actacacttt ctaaaagtat cttattatct tcaactatta
     1921 aaaccttcat aagtatcccc tacctttatt tgtctatctt aactttatga gattttaagt
     1981 caatatccac attggctttt tcttttatat catcatacgt atatcccact atttcaacac
     2041 tttttgcctt tgttgaacac aatatatcta tatctgtctc ttctgaaggc tttaaaatct
     2101 tatatgatgg cacacgattt actgttaaat attctccatt ttcattaact tctgctgtct
     2161 taagaataat atttcctaaa tcttttgatg atgaattttt tacttttact tgatacgtaa
     2221 ttccctcatt tgattcattt acttttttaa gttctgatgt agatagcacc tcatactgac
     2281 tactattttc tagcttaata ttattatttc ttatattaat agtattttct tttaaattaa
     2341 catacacaat cttaccctct gcctcatatt catatgcata aacttctaca ccctttacaa
     2401 aagttttatg cccacattct atgtaagcaa ctttcccagg cattaaagtc atgtccaaca
     2461 aagccttact atccgaagat ataatttttt tattctcatc atattcatta tatatcaatt
     2521 caacattgga tatattaaat gttgaattat tttctacctt tgttgatgta tctactttat
     2581 caccttcatc tatatttata atttctgatt ttcctatatt caatactttt gcatttccct
     2641 catctatttt tatctcattt ttatcttctg tttgaatatc aactgaatca ggctgttcat
     2701 ctttttcaca tgctgtcaac ataaaaataa atattgttaa tataatcatt agagaaattg
     2761 atttttttac tattttattc atattaagca cctcatatag tagtatttta tagtagattt
     2821 ttatactttt tcataaattc tttcaatgcc tgtgtaagta tttgatgttt ttcaaaattc
     2881 gaattactac ataatctttc aaaatcattc catatttctt tatctatacg tattcttgtt
     2941 gtttttaatt catctatgtg ttcatcatct atatgtacat cttttttatt agatactttt
     3001 ttaggcttta tattgtaatc ttttacttct aaataccaat catatacttc acaaagctta
     3061 tctaaatctt cttgagttat atttattttt ctatctttct taggcttaat attttgtttt
     3121 ggctttgcat tttttaaacc tgtatcatta aactcaattt gttcaacact tttacttaaa
     3181 gccttttcat tagaaatctt ttttttggtg cttacttttt ttctattact tatagtattc
     3241 tttttacttt tttcatactc cttagctttc tcttcttcca agtttctatt atccaaactt
     3301 ttattataat ttaattcgtc tttaaatatg tatttacctt tttctgactt atatcctttt
     3361 ttatttaaaa aagttcttaa agtactttga ctaatcttta gattttgagc tatctctgca
     3421 aatttaaatc ctttgctttg aagttctaaa aatttgtcaa ttctgtcttc attgttattc
     3481 attaatattc ctccgtcaac atcttcttgt ctttcttttc atacttctta ttatattctt
     3541 cttttctaaa tctactctat ttgattcaat tattttttgt agcattttat tataagtgaa
     3601 atcatctaaa ttattatttt ttatatagag aaaagtttcc tcttcacatt taataaaaca
     3661 aattgatagc aaccatgcca tacccatttt aacataatat tcttcacttt gtatattatt
     3721 acagtattca aatatttctt taatatgttt atcatcaaca taatatatta aaaacataac
     3781 taatgcaaat ctaatttccc atggattctt tgaataaaca tattttttaa gtatatcata
     3841 catattttct ttatattttt tcatagactt taaatcagaa caaaatccat cgcaaactga
     3901 ccaattatcg attttaggta taaatctttt tacatagtat aaagtttctt caaaattact
     3961 atttatattg ccaattacca taccttgtag cctaacttct tcatagtatg tatcctctgc
     4021 tacttctaaa aattccttcc aattcccttg gcttatttct tttgataact ttcttaaatt
     4081 aggaactcta atacctatta tattttctgt tccaggtata agctttttat taaaatctct
     4141 atattttata tcttgtatag acatcatata ttctaaaagt tcattataat ccaatttatt
     4201 ccattttacc ctatcaaaca tcatttaatt gctccttaat tccttttttc ttattgtaac
     4261 ataaaactct acaaaaaaag cttctaacta ttagaagctt tttcaaaaac ataagaaact
     4321 tttcaatttt aaatttaaac taaattaatg ctaatctcct acaccaaaat ctgtattatt
     4381 gtataaaact tctatatttg gattttcatc caagaattta tacttactaa caaaccattt
     4441 cactaactct tcatctcttt ttatactaga agaattattt ataaaaacat tcactgtcgc
     4501 tttttcaaaa gtatttagga taatctctat atctttatct atcatctctt ttgtttgtcc
     4561 ttttattcca accataatac aaggtgaatc aaaatattct tttacatctt gtggagtctt
     4621 aaaatttgca tttttattta aaatattatt tctaaaatca ttgtcaaagg tttcaactcc
     4681 aattttaaat accacaggaa tttcaaaata ctctctcatt tccttaagcc tatttttgta
     4741 agaccaatga ctttctaaaa ataatttttt tatatttttc tcttttataa tacactttat
     4801 tttttctaaa gtatccttag gtaattcaaa acagcttcca gaatttatga cttcaagaac
     4861 tccatatttc ccagttacgt tttttaaaac ctttagattt aatttattca tctcttcttc
     4921 taaattagaa ttatcatcta tataatcaca aaaagaacac tttccccata tacaaggaaa
     4981 tcctttaagc agaacaattt ctctttgatt tttatttgtt atctcactat atctatccat
     5041 tttctatcta ttttcctcca gtcaatgata cctttaaagt ttttggaact gcatttaatc
     5101 ctaaattcac taaaacaact gctaacagct tatctccata atcagtaaat acttgggtta
     5161 caaacacact aaaaacatcc cccagtccta acactttcaa gatttgcact atatatgatg
     5221 aacctgaaga ggtcatacct ccaaataaaa atgctgaaat tattgaactt attatagatg
     5281 ttggaatggc aaataaaagt actcctagtg gagtttttaa accccttaaa aaattctttt
     5341 taaatgctat tccagcaagt aatccggttg atatttgaac tggtgcaaaa tagagagaat
     5401 acacatcaaa cgtaattcca cttattaaac ttccaaacac acctgtaaca acagcgtatt
     5461 taggtcctaa aagtgaagct atcattatag ttcctattga atctaagtat acaggtaatc
     5521 ttaatcccat agctataaaa gcgcctatta tatttataga aataccaaaa gctataagtg
     5581 taatagtttt tacacatatt tttcttttca cactatatca ctccttccac agagtctata
     5641 atgtcttcat aacctttaaa aagcctcttt aaaaacatgt acataaattt cttctcatca
     5701 acttcattta gaacaattgc attaggattt tttttataga aattgaaaga atccactata
     5761 gactgaccca tagctattcc atcttctaca acttctacat atgattcaaa tcctttacat
     5821 atacttctat ctataaagta cgctactgct agagggtcat ttatcacaca gccaattatt
     5881 ccctcctgtt cccaatggaa atcaatataa aatctagtta tttcagttat atactttgcc
     5941 atcttcttat caagtctatt tataaactca ataatattag gagtaagtac aatttttcta
     6001 gttacatcta aacctaccat gtggattttt ttagataaat tcttgtaaac ataatctgct
     6061 ccatgtgggt ctacccaata attaaactct gctactggag agcaatttcc atgaatccta
     6121 aatgctcctc ccatagatac aaactcatcg agattttcaa atgctttctt atctttaata
     6181 agtgctttag ctatatttgt aagtggtgca agtgctatta ttgatacttt ttcatgatta
     6241 tataaagtat ttattataaa atccactgct ccattttttg ctttagctcc tacaaccttt
     6301 tgataaaagt tttctccaat accatcttct ccatgtgtat cttgagctgt tacaagtttt
     6361 ctttttagtg gtgcttcttc tcctatatat actggaatat ttagtgaaga acacatttga
     6421 agtgttttta gtgcattttc tgcacctata tttgctggaa catttccaca acatgtggta
     6481 attccaatta cttctagctc tggtgagttt aaagccagaa gaattgccaa agaatcatca
     6541 attcctgggt cacaatcaat tattactttt ctcttttcca ttttttatcc tccttgattt
     6601 gtggtcgagg agaactacac atcttttttc cactttcaaa aaggtgtgtc taagggtatt
     6661 aattatatac tgccactata taattcctta gttttttata cttggagttc tcgaacaagt
     6721 acagatgtaa aatcatattt ttaggctact tactatagac tcttaaaaac tatagactgt
     6781 taaaaaattt ttaaacatct gatttaatag ctataaaata aattttatag cataaaagaa
     6841 tttattatat tttaatgtat cttattaaag tttatttaga attatgaacc aactttaata
     6901 agatgtggcg catttaaacc gattattatt atacaataat atcttaaata ttacaattaa
     6961 taacattaat ttattatcca taaaaatata ttaacttata ttatttaata atttattgac
     7021 agtattaaaa ttaaattata caataacagt gtaaattaac ttaacaccgt taagcaaaga
     7081 ggtgattata tgagtatcaa agaaagacgt aaaaatgaaa aagaagaaat gaagaaaaag
     7141 attatggatg ctagcatcga aattataaac caacatggat atgaaaattt atcaataaga
     7201 aaaattgcta caaaaataga atattctcca actacaattt atctttacta caaagacaaa
     7261 gcagagatta tcagcgatat gaccaataaa ctttataaca cagtagaaag taatgccatt
     7321 gacattatga ataattgctc atcactacca atagataaac aaatcataga aattatgact
     7381 agctttataa aaactctttc tagtgaacca gagatggcaa aatctatcat gtatagtaga
     7441 atgaatatta tatttgcatc tgaaaataca aacaatacgc ctagcaataa tggtataaaa
     7501 atgcttgata aattcctttc cattggaatt gaacaaggaa tattcaaaaa aaatatagat
     7561 aaaagctcat ggatgcttat aagtgcattg ttaggattcg ttttatgtgt tgttgaaaat
     7621 aaactatatt ctttacataa tttttctcaa cttatagaaa atttcttaga tattttagtg
     7681 ggaggacttt acaatgaaaa ttcgcaacaa ggctactaat aaaaagaaaa aatatgtaaa
     7741 aatatctatt gctctattct ttgtatttat atgcattatt attgtaattg taagcaactt
     7801 aaagccagaa aacttggtag taaaagatat agatattaat aatgttaaaa atggcattta
     7861 tactggaagt gctgataata acttggtaaa agctactgtg tctgttgaag ttaataatgg
     7921 taaaatccaa aatattaata tcttaaaaca cgaccatctt ttaggtaaac ctgctgaaaa
     7981 aattacaaca agtattatta aacaacagtc tttagatgtg gatgctataa cttctgcaac
     8041 ttatagcagt aatactatac gaaaagctgt agaaaatgct ttaagaaagg gagaataatt
     8101 atgaatacta ttattatata ttcaagtaaa tatggttgta caaaagactg tgcaaatata
     8161 ctaaaaaata aactatcaga taatgtcact attgttgata ttaataataa taataaaatt
     8221 gagttatcaa aatttgataa aattattatt ggaagttcta tatatgttgg ttcagtttca
     8281 aaaaaaatac aagtgctatg taatgataat gtagagttat taaacaaaaa acaagttggc
     8341 attttccttt gctgtggctt ttctgaacaa gcagataaat atttaaaatc aaattttcca
     8401 tcatccttat tagaaagtgc aaatgctatt ggaatttttg gtagtgaagc tcgattagaa
     8461 aaaatgaaat ttttagataa acttattatg aaggctgttt caaaaggtaa ttatgacagt
     8521 tttagaatat cacaggataa tatagataat tttttaataa atcttaatag ctaaaataaa
     8581 actaattatt tctatgataa attcttttat ttataagtaa tattgctcaa aatagtcttt
     8641 aaactttatc aaaattttat ttttcttagt gaaatctaat gaaactagca cttaatatat
     8701 gctttattaa tcataacaaa tatgttttat taatcataac aaaaagagag tgtctaatga
     8761 actaaaaaat tcattagaca ctctcttttt gtatgaaatc aaatatattt ttatcatttc
     8821 aaaagtgaaa aatacacttg tctctatgtt tggcacattc tctttttata atataatatc
     8881 taatttaaaa cctatttcaa atattgacat atacttaaac tatagactta caaaatcaat
     8941 tcatattagc ttaaaatata atctttgtta ttcaaattcc tatacacaac cattatttac
     9001 tttgatactt taaaacatct tccctatttt ttattaaatt ttataataat agtcctatta
     9061 acgcaaatac tataaaaaga gtttaacttt atccattaaa taaatttaaa ttaaaacata
     9121 tagaaatgga aggagaacaa tttatgataa aactaatcgg tatattgata gttgtaattg
     9181 gatttatact taaaattgac acattattta ctgtattatt agcaggagtg gcaacaggaa
     9241 ttgttgcagg attagatttt aatcaaattt ttacaatttt aggagattct tttgtctcaa
     9301 acagaggtgt atcattattc atattaacat tgccagtaat cggtgtatta gaaagatatg
     9361 gtttaaaaca aagagctgtt tctttaatag aaaaattaaa aagacttaca acaggaaaag
     9421 tacttactat atacatgata gctagacaaa tagctggtgc tctatcaata agaatgagtg
     9481 gacatcctca atttgtaaga ccacttgtta atcctatggc acaagctgct ggtttaagta
     9541 atagtgatga actaaaagaa tcggatgaag aagccataaa ggcattatct gctgcatcag
     9601 aaaactatgg aaatttttat ggtcaaaact tatttgcagg tagtagtgga gtattactta
     9661 tagcatctac tctgactcaa tttggataca atgtaactgg acttaatatc gtaaaggcta
     9721 gtactattat ggcagtaata gcacttgtag tggctacaat ccagtttacc ttatatgata
     9781 aaaaattaaa caaaagtcat aaaaaatagt tttatttagg aggaataaaa atgcaaaatt
     9841 ttataaacat atcattagaa atcttttacg cactaatggg atttttaatg attgttatag
     9901 catataagtc ttttactacc ataaataaca ataagaaata tggtacatca ttattttgga
     9961 tacttatatc actgccattc atatttggta gattgattcc agccaatata ataggaataa
    10021 tattaatatt atctagttta ttaacacttt ctaaacaagt tgtatttgca aagtatgaag
    10081 aaccagatga aaattttgga aaagaacaag cagacaaact taaaaataaa atatttatac
    10141 catcattaat attagcattt gctgcagtag tagtagctat gagcctttct aattttgata
    10201 attcttctca atttgcaata ggtgtgggtt caataattgc attaatatca gcccttataa
    10261 taactaaggc aaaacctgct acatcagttc aagatggctc aagattactt caacaaatgg
    10321 gacctgctag tatgttacca caacttttag ttgcattggg agctttattt actcaagccg
    10381 gagtcggtga agttatttca accatgatat ctggtgtagt ccctgctgat agcagattat
    10441 ttggtgttat agcttatgta ttaggtatgg ttatatttac catgataatg ggaaatgcat
    10501 ttgccgcatt ttcagtcata acggcaggaa ttggtattcc ttttgtattg tctcaaggtg
    10561 gaaatcctgc tataattgga gcattagcat taacagcagg atattgtgga actctactta
    10621 ctccaatggc tgctaatttt aatatagttc cagcagcctt gctagaatgt aaaaatgatt
    10681 atattgttat aaaatatcaa gctccagttg ctttggtatt aattatagcc cacatattag
    10741 taatgtactt tttaggattt taatataatt aggaggtaaa ataatgaaaa ttttgttaac
    10801 aggatttgac ccatttggtg gagaaccaat aaacccagct caagaagcag ttgaaagggt
    10861 caataataat ataaacggtg cagaaatcat aaagataact ataccaacag ttatgacaaa
    10921 atctgttgaa gctatagata aagctattca agagcacaat ccagatatag taatatcagt
    10981 tggacaagct ggaggtagat ttgacattac acctgagaga gttgctataa atatagatga
    11041 ttttagaata aaagataatg agggtaacca ggttatagat actattataa aagaagatgg
    11101 tgaacctgca tatttttcaa aattgcctgt aaaagctatg gtaaaacata tgaatgaaaa
    11161 taaaattcca gctagtgttt caaacactgc aggaacattt gtttgcaatc atgtgatgta
    11221 tggaattctt tatatgatag acaagaaata tcctaatata aggggtggat ttatacacat
    11281 cccatataca acttcacaag taatagataa aaaaaataca ccattcatgt ctttagaaga
    11341 aatagtaaaa ggcttagaat tagctataga agcttgtatt atatataaag aagatgtaaa
    11401 agaaattggt ggtgaaattt cataataaat tttttagtat ttttataaat taaaaatact
    11461 aactattaat ttaaatatag actgtgagta gattattcaa acaattttac tcacagtctt
    11521 tttatggtat ctacagatac aaaattaagg tctattcctc tctccccact cacacattgc
    11581 atctaaaatt ggaatcagag attttcccct ttctgataga ctatattcta ccttaggagg
    11641 tatttgagga tattcagtac gaataatcaa gttatctgct tctaattctt ttaatgataa
    11701 actcaaagtt ttataggaga tagtatttat ataacgtttt aatgcattat atcttacaac
    11761 ttcaaattct acaagacagt aaagaattat catcttatat ttaccactaa tcagtgaaag
    11821 tgtataacta aatcctgttt cacttaaatc tgtatttgat atacagtcta tactcatata
    11881 ttacactctc cttttggtta gtattgaaca aaaatgtgcg tacttgtttt tagaataatt
    11941 tataataaaa ttatagtgta agaataattg aaagtcaatt ttataatagg aggtgtattt
    12001 actaaaaaaa aagttatttt aaataggatt ctaagattag acatttctat ataaattgat
    12061 aatattcatg aaaatcctat tttataaaaa ataatatctc ttagaaaatc tattaaataa
    12121 aattcattgg aggaaattta taatgaaagt tttattgata aacggtagcc caaaccaata
    12181 tggatgtact tatacagcac taaatgagat tactaaagta ttgagtaaac acgatattaa
    12241 aacagaaata ctgtatttag gtaaagaaac aatcccagga tgtattagtt gcgcatcctg
    12301 ttttgaaact ggaaaatgta ttcgaaatga taaagttaat aaattgattg aagatctgga
    12361 taatattgat ggtattatta ttggttctcc tgtttacttt tctagtgcaa ctggtcaatt
    12421 aacttctttt cttgaccgtc tatttttcat agctggaagt cgcatggcta caaaattagg
    12481 tgcttcagtt gtgtcatgta gacgtggtgg tgcaagtgca acatttgacc aactaaataa
    12541 atatttttca atcagcaata tgcctattgt atcatcacag tattggaacc aggtacatgg
    12601 ctttactcca gaggatgtta tgaaggatga agaaggatta cagactatgc gaactctagg
    12661 agaaaacatg gcatggcttc ttaagtgtat atcagcaggt aaaaaagctg gaattaaaga
    12721 accacaatat gaagaaacaa ttatgactaa ttttataaaa taaataaaaa atgtactaat
    12781 attaattaaa acaaaacact aatttataaa taaaataagc ataaatgtag gataaaaagc
    12841 actaaaacag aggtattgaa ttttatatca aacctctgtt ttattattac attaataacc
    12901 aaaccatgta taacatcata tatttctaaa taaattataa tattatattc taatgttatt
    12961 gaaattacaa taactgaatt tctgctcata aatttaaata ttctacaaat ctcatctaaa
    13021 taacaatttt aatagaccta aaacaatcct catactgttc attttgtatt aaaaatatca
    13081 cttacaatca aaaaccattt attaagtata ttcctaagat atacaatata tatacatgga
    13141 ttggatagta taaataaaat aaatacttca tactcttccc tttttctcca ttgtaaagta
    13201 acattaaagg tagagaagca atcatcatcc attggtaatt ttgtaaaata gaatttttta
    13261 aactataatc tccatttgac attgttgtaa atataaatat acacattaaa acataacaaa
    13321 tactcaaact gaacttttta cctctacaca aataaaaaat aatcccaagt ataatccaaa
    13381 ttggtccacc ttctactaaa aatggtactg gtaccaaaat cataaataaa gcaataactc
    13441 tgttagtgac tttaaaaagt aaagctactg taaatattcc taaaattata ggaatgatta
    13501 tcatcaataa tcctataata aaatatttaa tttctttctc ttttctaaat ttctttatga
    13561 actctattgc ttgtaaataa atcgctatta aaaataatgt tgaaaaaatg ttatttataa
    13621 ttatagctcc ttctggatgt gaaaatacat tattaattat ttgatttcct atagccataa
    13681 taacagacca aatatacaat ctacttatat atttttttct gttactagtg tgataaaatc
    13741 cttcaacagc catgaatata aacagtggtg ctgatattct gcctacccaa tgaaaccaaa
    13801 ttggtatttg cattgtttgt ggcataaatg ctgctatatg gtcaaatgtc ataaatatta
    13861 atgctaaaat tttaatagta aacccactta tacctttttt aaaaaaatcc atatcatatc
    13921 tcctaatttt gttttatctc tataataatt tttgttccta ttccaatttc actacttaca
    13981 taaattttac ctttatgaat ctctattatt tctttagaaa tagccatacc aagacctgaa
    14041 cctttatgca tctcacctgt attagtacct ctataatatt ttttaaaaat atgtttcaaa
    14101 tcacttttgc ttattccaat tccattatct tttattataa tttctatatt atcttttttt
    14161 acaatttcta cacttatcaa agttccttcg ctattatgaa ctattgaatt aaatataaga
    14221 ttggttatag cccttctgaa taagattgaa tctacatata cttcaattaa atcttcatta
    14281 ctttcaaatt caatattcct atttttatat ctattatcat ttaaaatatc aattattata
    14341 tctctgacta aactgactaa atttattttt ttcttgtcca gaactatagt attatttttt
    14401 aatcgagtag ataaatttaa atcatcaact aaatctttta tatacttaga cttattatat
    14461 ataatttctg tatactcttg tatttcatct tcttcaaact cataatcttt gtcattaatt
    14521 atctctgcat acccttgtat agatgctaga ggtgtcttta tatcatgtgt tatatttgcc
    14581 agccattcct ctctcaactc ttcattttct tttctctcaa cttcatttac tcttaaagta
    14641 tcagctaaca tatttatatt tttaaaaact tcttcatata tacctctgtc cttaagatat
    14701 aaactataat ttccattagc catagtctca atactccata gtacgcttga aattggtttt
    14761 gtaagttttc tactaaataa atatcctaca cctaaagcta ccacgctatc aattactagt
    14821 gttataatga taactttatt taaagttttt ttaatgttat tttgagaata ggttaaaatt
    14881 attcttgata tatctctact aggtatacct actattatgt ttaaatgttt tttgtttaaa
    14941 tatttttcta gtacaaaatt aacatacttt gtttctatat acttgtaatt attcaccatt
    15001 tgaaagggtg tatatttttt tggagtatcc tttggcacat ttactccata aacttcctct
    15061 cctaaatcat ttaaaacctg tatccaggaa tttgattttt ctaatttttc agctccaatc
    15121 ttagatagtt taaattctcc atctttttca tataaatctt tttcaaaaga acgtgcaaat
    15181 tcttcaggat tatttccaga atctacaact ttaaaaaagc tattagttga aatcacatac
    15241 aatatagata tgatatttat aattactact gatatagcta caaacacaat tgtaaatata
    15301 aaatttctag taatcttcca cttcatattc taatcttcct ttactgctaa tttatatcca
    15361 agacctttta ttgtcagaat atattcaggt tttgaaggat tatcctctaa tttttcccta
    15421 atttttctta tatgaaccat tatagtattg tcaaatccaa cataatcttc tccccacact
    15481 ttatcccata gtttttcttt acttataatt tgattttgat tatgtgcaaa taaagatagg
    15541 atttttagtt cctttgcaaa cagtcctata gattttccat cttttataag ttctgcccta
    15601 ctttcattta atatatatgg gccaaatgat ataatttttt cttcattatt atttagattt
    15661 ttactttcgt tttgagcatc actaaaataa cttaatcttc tcaaatgcgc tttaactcta
    15721 aaagccactt ccttagggct aaaaggtttt gtaacataat catctcctcc aatcgctagt
    15781 ccaagtaact tatctaattc ttcggtttta gctgataaaa atattattgg agaattggag
    15841 gtttttctta tttctttaca aatatcataa ccttcgccat ctggtaacat aatatccaat
    15901 acaatcaaat caggattaat acttttaaat aattctaatc cttctttttt agtttttgca
    15961 gtatatatat tattaaggcc ttcttttttt aggacagttt ctaaaagctt caatatttct
    16021 acttcatcat ctattattaa aacacgattt tccataaaca acctcctgta ataatttaca
    16081 tatatattag catatatttt atctaaaatt catttatctt atttttaatt aaactaaaat
    16141 ataaataaaa ttactattat ttttagttaa aaccttttgc ttgatgtaaa attttcatat
    16201 gttattttag ttaacactat cattaatata attgagatta ctatagaaaa aactatcaaa
    16261 atacttggta cattatactt aaccatttgt tggctcatca taatccaatt tggagtcact
    16321 gacataaatt ttatagcttt atctggtata aaacctacac taaagtatgg aattgccatt
    16381 atcaatccac ctagtataaa tggaattaca gccgatttaa atatagatga aagtgttaag
    16441 cctatttgtg caaatataaa agaagcaaaa atagtagtca atataacaat tatatacatt
    16501 tgtattactg taagatttaa attactattt ccaaagtacc ataagttatg aatcgattca
    16561 tttaaatttt taaaatcaaa aaaactaaaa cctctaattc ctactaacaa tataaaagaa
    16621 atattaataa tagataaaat taatccatta gctactagtt ttgataatac tactgatttt
    16681 tttccctttt tagttgtatt tattaaacct gtcatattag aatcatattc tttaatgtaa
    16741 tttccagaag ttattataaa cattatcaaa cctattagag gtattgagcc ttctatcttg
    16801 taaaatatat ctgcataagt atctaaaaca tcaaactttc taatcagaaa aaatccaaaa
    16861 aatattaaaa acagccaaat tatccaaaca ctctttgatt ttaatatttt tatcatttca
    16921 gctttaacta aatacatcat ttctactaca cctcccttgc atcttctaaa tcaaaataaa
    16981 acatgtatac atcttcgaat tttgcttgaa ctggttgtat attatcctcg cttggaatat
    17041 cctctgaaac aattctaagt actattgaat taatatcact ttgaatactt acaaccttat
    17101 atttagattg tatatcatca acttcacatt catttttaac ttgaacatta tatactttat
    17161 tttccatgtg acttaatatg tctttgtgtg ttcctttcat taggagtttg ccatctttaa
    17221 tcattattgt ttcctttgca actgattcta tatcggaaat tatatgagta gaaagtatta
    17281 ttatcttatc tctagacatt tttgctatta aattcctaaa tctagctctt tcttgtgggt
    17341 caagacctgc tgttggctca tcaaggacta ttatcttagg gtcgtttagt aaaacttgtg
    17401 ctatcccagc tctcctcttc atacctcctg aaaattttcc tatagactta tttctcacat
    17461 cataaagacc tactaaatct aataattctc ctatcttact atttaaatat tttcccctta
    17521 aaccttttaa agctccaata tactgtaaaa attcttttgc tgtaaaattt ttataaactc
    17581 caaattcttg tggcaaatat cctaaaatat ttctataatc agcatccatt ttaaatatat
    17641 cctcaccatt ataaagtatc tgaccttcat caggttttat caacgttgtt atttgtttca
    17701 ttaatgtaga ttttcctgct ccatttggtc ctagaagacc ataaactcca ttttctagag
    17761 ttactgtaat cttgtcgttt gctacttttt taccatatat ctttgaaaga ttttctattt
    17821 ctaatttatt catcttaact ccccttttat ctacttatat aatctgattt tattactaaa
    17881 aaacataatg acatagcacc tatcaatatt gccatcaaaa gtcctattgc tatattgaca
    17941 atgtctatat tcactttaaa tatcataata tcacctagat aatttcctat tattttatta
    18001 aaaccaaata tcaaatcata ataatttaca tttgatacaa ctgaaagtaa ttttttaggt
    18061 aatatatgga ttaccgacat tatcttagtt atagatataa taaatataaa aaaacttatt
    18121 gaagatattg aagacttact tataaaagac ccaaatatgg ctatcatggc ccatccttca
    18181 aacatcaaaa gctctatgcc tatatttaat attacatact ttgttatact taaattagtt
    18241 ttcaatgcaa ctacattgtc tactattcta aaagattcta agtctccatt aacaggtact
    18301 ccttgttgca tacaagttat aataaatatt cccattaaat aaacagaata aattactaat
    18361 ggaactaata aagcaacaaa tattttagaa tttaatgctt ttttcttctc ttttgatgat
    18421 agtatgatat cttttaccga agtaacgact tcatctacgt aaatattaga tataattata
    18481 gatataatga ttaacattcc tacatttata agtgaatttg taactctata gttaaatact
    18541 ttccaaaaac taatatcctt atattcattc acacttagat tatcaagttt tttctttgac
    18601 attaattcaa tttttttaga aaattcacct gtatctgttt gatttgaaaa ctgctttaaa
    18661 acattaatct tattttgaaa tttctcatta cctatgtcga taccacttct cgtatcttct
    18721 atacgtcctt tttctttatc tatataataa ctttctgttt ctaaaacagg cgtaataaag
    18781 atactaatca ttagtattaa cactaatatg cctagagata taaacatact cttagattta
    18841 gccaattttt ttatttccca atttaccaat atatttctcc tcctaaatca ttttaattac
    18901 acatatatat taaaacttaa atcttatata aatataatac taaccttaaa taaagcttaa
    18961 attattttat aatttatagg tgtgtttatt attggagtta catttattat ttttctggga
    19021 aattatacat tttcaattat ttttattatt tttgatattt ttattgattg gaaattttat
    19081 tgttgttcaa attgtagtta ttctttaaat ttaaagatgg agttttttaa gaatagaacc
    19141 tactgtcctt attatggaaa gattattaaa tagttgcata taactttatt tatcttgaat
    19201 cttattttta aaaacaatta taattttaga atattttcta ttctcaaaca agcatgttga
    19261 ataatgaagc atcttctagt attatatact tgtagaataa aactaaattg gtaaaactgg
    19321 gaatatttaa ccttaaggag ttaagttata gaaactagta ctaaaaaatt ttataaatta
    19381 tgttaattga ctaatagaat gcgacttttt atttttacta aattttttag ggggatggat
    19441 aatatgttta ttggagaaat agacaaatgt acacatatac taactgctta catcagtagt
    19501 tcatatgatt attgtaattt tttagataca cagttagatg attttatatc agaatatgga
    19561 gaaacggtag ttgaaacctg cttacatcaa gtcttattat tagtaagtag atacaattaa
    19621 aactaaattt ttctagaaaa acctttttag atttatctac tctaataaat atataatttt
    19681 ttgtacttta taagtaacta taacttctgc taaagtaaag atgtattggg agtacatctt
    19741 tactttccca ttatagaagt taaaagcata caccataaaa ttaatcatcc aatacaaatt
    19801 atatatttcc tatgtctaac ttaatttaca agaatcattc tatatgcata ttctgcaatc
    19861 cactaaacat ggctctaaac ctttactatt ttatacattc tctataaatc atacaaatca
    19921 tatataaaat ccccctaata tgtttaaacc acctataaaa taacaccaat atttagaata
    19981 ttcaatatca actgcataac tggtcaataa aaacgtataa ctagacaaat ttcaatattt
    20041 atataaataa tacaagaaaa acaagcattt tatttatat
//
LOCUS       DAMJVG010000072        19808 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.072, whole genome shotgun sequence.
ACCESSION   DAMJVG010000072 DAMJVG010000000
VERSION     DAMJVG010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19808)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19808)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19808
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.072"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            156..1661
                     /locus_tag="PC512_002820"
     CDS             156..1661
                     /locus_tag="PC512_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HDF2442553.1"
                     /translation="MKIQNTEWGYIEWKHTYDENNPKQAMNIYIAVTMPGKKHFNHVH
                     YGQEQMIYILEGEGLYIINGVWKPFYQGMIFYIESGSTHETINTGDREIKELIVSNNV
                     DDVGESEVIDINPNNYLKKTLINYSESTLNLYAAVESIRGQFIDPFKIPLIIYDDSWN
                     IVLKNPYFPLFCFEKCNPMKFPQNCDCMNQKSSNQFVCEYGITIYNIPILYKSNSIGV
                     IRGGYVLLSDLNLDTEHNNLYDIPEGAARSIKRLLKQISKNIINFCSFNDIRKDLQEK
                     EKTIARTYHYGEQLEMNLKVAQDMVTNLRINHHFLFNTLNSMASIALDDGSYDLYSAI
                     IDLSRMFRYTMRSDLRFVELESEILYIKNYLNLQKLRYGDALKVKYLIPEKLYNLSVP
                     FNFIQPIVENAFTHGFRDIDTEKRIEIIARLDSQYAIIEIHNNGTILDGNNIDKIKAG
                     IRSNNGHGLSLIYTKFTSAYGNNFDMDIKSSDNEGTYIMIKIPIENYKEYV"
     gene            1775..2473
                     /locus_tag="PC512_002821"
     CDS             1775..2473
                     /locus_tag="PC512_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HDF2442554.1"
                     /translation="MRRALIIDDEEAVLKIITHFIEMKDMPIKIVGKATSGDEAVDKI
                     IGLEPDIVFIDIQMPIYNGLEVIEKTSHLSKKINFVVITAFNYFEYAQKALRLNVKDI
                     LLKPLDMKEFTKSVEKIIGYQYTNNDLLNEILEYINLNYSNDLKLNDCARLFLTNPSN
                     ISRIFKSNLNTTFISYLNHIRIEKSIELLENTTKSINEIAEIVGYNSLNNFYKNFKIE
                     KGMTPKVYKLNTKN"
     gene            2758..3846
                     /locus_tag="PC512_002822"
     CDS             2758..3846
                     /locus_tag="PC512_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442555.1"
                     /translation="MSDKVNMKNIICIAGAYLATAIGSGFATGQEILQFFASQGYMGL
                     IGALISMVLFSFLGAEVITRGRELKLKEPTRIYTFYCGKILGKFYEWFSPIFLFGILI
                     VMISGAGSTLTEYYGINPYLGRVLMAVATLITVSMGLEKLVSILGRIGPVIAVFTIAV
                     GLISLFKHFDGLSMVGEAMKNIEVTKASESPIVSGVIYNTLNIIVMIVFLTGMGASIE
                     SKKDAFWGGLLGGIVFMTAGIVMYLAMISDIGNLYMKEIPSLYLADNISPIVGVCFSV
                     ALILGIYTTAVPLLWSVTNRIVEDEHPKFKLVTTVIAILACIGGFLPFGKLVNILYPY
                     TGYMGLLILVCMVYKAITCRKKSTQSQE"
     gene            4085..5275
                     /locus_tag="PC512_002823"
     CDS             4085..5275
                     /locus_tag="PC512_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2442556.1"
                     /translation="MHELILISEKYKEDILDFFTDIHMHPELSFKEFRTTKAIKDLLV
                     SLDIEILDLGMETGVVGLLKGKYDGPTVALRGDIDALPIYEEVDIKYKSRYDGIMHAC
                     GHDIHTSCLVGCAYVLSHIRDSLHGNVKFIFQPAEEVNKGAKMLVERGVMENPKVDAI
                     FGLHNHPDIPCGKIGVKLGGLMAAVDTIKIEVNGFGGHGGIPNRTIDPIVASSAIIMG
                     IQTIVSRNISPLESAVISIGTINGGTANNVISEKVDMTGTCRSFSNEVRKKISENLEN
                     IVCEIARGYQATAKLDYLFDLPAVINSKEMYAIACKSVCDLYSEDAIVDPIPSTGGED
                     FSIFMEKAPGFFYWLGVGNKEQDCIYQWHNPKFKADKNSILVGTNVLCQSVINYMDKL
                     KNKI"
     gene            5366..6868
                     /locus_tag="PC512_002824"
     CDS             5366..6868
                     /locus_tag="PC512_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HDF2442557.1"
                     /translation="MRALNVVERAGNKLPDPVTIFLLLCIIVVILSAVISNLGVEEIH
                     PSTKEVVKVVNLLEKEQIQSYLGSIVTNFQSFAPLGLVLVTMLGAGVAEKSGFMEVLM
                     KKGISKVPQKLVTVAIVFAGMLSHTAADVGFIILPPLAALVFLGIGRHPLVGMFAAFA
                     GVAGGFAANVMLSTTDVLLAGFTIPAAQMMDPSYQGNPAMNLYFAFISAIVLTFAGAF
                     VTEKFIAPRFTKYNDSTNDKDIQELSELENKGIKYALLSLLVVVVVIVALCIGDNAFM
                     KDPETGSILSSNAPLMKGIVPIITIIFLTPGLVYGKVSKKIKSDKDLVSMMGSSMSDM
                     GGYIVLAFIASQFINLFNLSNLGTILSITGAKLLAESGIPSYGLIIGFILLSGFINLF
                     VGSASAKWAILAPIFVPMFMLLDFNPALTQIAYRIGDASTNPISPLFPYFPVILAFAR
                     RYDKDIGIGTVISNMIPYSVVFTLIEIIILLLFMGIGIPLGPGGGISYVL"
     gene            6940..8196
                     /locus_tag="PC512_002825"
     CDS             6940..8196
                     /locus_tag="PC512_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HDF2442558.1"
                     /translation="MLKTTKISDPELYKIVADELVRQEHNIEMIASESTAPTEVLELS
                     GCVFTNKTEEGYPGARFQAGSEEADKLETLAIKRAKEVFGAEHVNVQPYSGSTANYCV
                     YSSILKPNDTVLSMRLDQGGHLTHGSAVNFLHDIYKYEFYGVDPNTGRIDYDALEAKA
                     KECRPKLIIAGASSYPRLIDYERISKVAKEVGAYFMVDMAHVAGLVAAKVIPSPVPYA
                     DFVSSSTTKTFCGPRSGIVLCKAEHAKKLDKGVFPGTLGSIHLNTVAAKAFSLLYLST
                     DKFKKIMEQVVVNAQTLASELISHGFSIVSGGTDNHIVMVDLRSKNLTGKQFEKALEY
                     VGITVNKNVIPDDPQSPFVTSGVRIGLTSISQRGLKEKEVIQIAGIMNKVAENIDNKE
                     VLDECKAEAQELISKFPLYPEGYFED"
     gene            8368..11142
                     /locus_tag="PC512_002826"
     CDS             8368..11142
                     /locus_tag="PC512_002826"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HDF2442559.1"
                     /translation="MRYYNKPTKEVLKYLKTNPEIGLDDNEVEERKLRYGLNEFTIKE
                     GRTFWDELGESLTEPMILILIGAAVISSFVGELHDALGILGAIFIGISIGIITEGKSK
                     KAAHALSKLTENIEVKVLRNGKIIKISKNDLVPGDIVYIETGDMIPADGRLIQSINLK
                     LREDMLTGESDDVAKNADAVLDMEVVYSKTEIIEQDAIPAKQVNMVFGGTLVAYGRGI
                     MVVTHTGDKTEMGKIAQNLSNEDQQTPLQIKLGKLGAKIAGISGVIATLLCMFMIIQM
                     QRKGMLILDTSSVLSFLQSLEPAKNAYMVCIALIVATVPEGLPTMINITLAITMQKMA
                     KINALVTKKEACETIGSVSVICSDKTGTLTQNKMMVEVAYVDGKYISGGEYQSNSYFE
                     QNCIVNSTADIEKEDNSFKYIGSATECALLLYHNDKNYNEMRKQTYLISQIPFSSEEK
                     KMSTLIRQEDSDILLSKGAPEVLLKKCSYVQQGKNIVPITPKVEKSILDEIKKLQIKS
                     MRTLGFAYKKMSNSKTEVAMTSEGELNLIGNSRSYMKEDNLVFSGFVGIVDPLREGVK
                     DSIDKAFNAGVDVKMLTGDNINTATAIGNELGLLNDGKKAVEATYIDVLTDKELREEI
                     KGISIVARSKPDTKMRIVSALQKSGEVVAVTGDGINDAPALSQADVGIAMGISGTEVS
                     KNAADIILTDDSFSTIVEGIKWGRGIYENFQRFIQFQLTVNIVAFIIAIISQLTGKDM
                     PFTTIQLLWVNIIMDGPPALALGLEPVRDYVLKRKPINRHSGIIARSMFVNIIINAIL
                     IITIVFTQSAFNILGATSEEQGTVIFSLFAFSALFNALNCREFGLNSTIPNFFKNKLA
                     LQIIVVTGIIQIIFTQVFQSFFNSVSLDFDMWIKIILFASTILLSNEFVKLILRTMKN
                     SRTMNFNSKN"
     gene            complement(11243..11392)
                     /locus_tag="PC512_002827"
     CDS             complement(11243..11392)
                     /locus_tag="PC512_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HDF2442560.1"
                     /translation="MFFISYIYTKSPIEFDTPLQKEAYKILQKLDIDFECVDTDEAIT
                     MEDCV"
     gene            11767..12945
                     /locus_tag="PC512_002828"
     CDS             11767..12945
                     /locus_tag="PC512_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HDF2442561.1"
                     /translation="MFSKILVKTFIRDSENVQNTDVRNKYGYVAGVVGILSNLLLFVI
                     KVFIGMLTSSIAIMADAFNNLSDMASSAITMIGFKLASKPADKEHPFGHGRIEYLSAL
                     IVAFMVMLVGLQFVKSSIERIVNPIPVKFEVIPLILLIASIMIKIWLSRFNKFMGNKI
                     DSSALKAVSLDALGDVFTSSCVVISFIVARFTNFPIDGYVGIVVSLVILYAGFSLVKD
                     TINPLLGEAPDEEMVNSIIELLLSYKYIIGTHDLIIHNYGVGRCIASIHAEIPSNIDI
                     MEIHEIIDTAEREISEKLDIYLVIHMDPICLEDKEVMSAKKELEEILKKNSLVKSMHD
                     FRIVGKGSKKNLIFDIVVNPSEFSKNMSEDDLKEDITKLVKEINPEYNCVIVVDKDFI
                     "
     regulatory      13072..13157
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            13275..16193
                     /locus_tag="PC512_002829"
     CDS             13275..16193
                     /locus_tag="PC512_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021362860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HDF2442562.1"
                     /translation="MKKGNRKALLISLIMILSMVVSTIYPTVSYASELGENSQIQSGS
                     TNSSTGEEKESDNKKPEQTPEKDKATDNKKPEQTPEEEKPTDNKKPEQTPEEDKSTDN
                     KKPEQTPEGEKPIDNKKPEQIPEEDKSTDNKKSEQALEDEKPLDNKNTEKTPEEDNLL
                     EDENLLKVLEEELNEENEDYGFVVKINNNTIETESMKKISFNLTYTPTSKGIQAGDSI
                     TFKVPDVFNKVNLDYTSECFDKTESNGEYTLTFRELPNGQSVMQGKIGLEAYVKKVDE
                     DTNAKIHIETTGKIESGSGDIDVEIKPGDKTDVPDAKGTLKKLVEGKKSTTVFMPVKN
                     KDINYSIQVNEKQEELKDIILYDELPEGLTLINGSVSVVTSDGKEVSDFNIEQSKNSI
                     SVNFGNIDKSYTVKYKARISDKNAKHGNKYKNVARIESDGKKIQEDDATVSIFDRGDD
                     YLLTKGHSGATNITQVGQVINYQISINDDKSPISNVVITDNIPEGMRLTTSGEAGHDF
                     RVVEIPMNGSWTPWSKEKIANNISYKVEEKRNESGQVDKVITGFTINLSKEEVESKFF
                     IAYTLKVISIEDSYINRAVLDANNSEIDKNDEINFKKNSGLISAKKEVDKKVLNSSDN
                     QIVKYKINMSTYGVYDAGQVNLLDEVNSALEISNIKYSDNLELKKEAGDGKNTIRLVN
                     KYEFKQIKEGEPVQSWVTFDADFTNVKVGETIQNVAQINGSSPPGVETTKQGYAFEAK
                     KVDALDKNVLSGAKFNLEDAFGNIVVKDLVSDEDGIIQSSIKKPGTYYLVEIMAPSGY
                     EKLKDKIKVEIGNKDIGRIVDIGNIENIRQENPPVNPPAPPNTDEPIVNPPVPPSTDK
                     PRKPSSSSDTEDTIVINPPIPPSEDIINPPIPEVLNPPVPPSEEMIETPVKQIIPIPE
                     VVKPSVSEEKNNKVKDDTLVNPPVPPKTGDSTTIIGEILLVIGAIVGLIVLRRNKNTN
                     "
     regulatory      16379..16464
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            16564..17226
                     /gene="zmp1"
                     /locus_tag="PC512_002830"
     CDS             16564..17226
                     /gene="zmp1"
                     /locus_tag="PC512_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease Zmp1"
                     /protein_id="HDF2442563.1"
                     /translation="MRPSKKLLIAIISIFLISSVPVSAHADSTTIQQNKDTLSQIVVF
                     PTGNYDKNEANAMVNRLANIDGKYLNALKQNNLKIKLLSGKLTDEKEYAYLKGVVPKG
                     WEGTGKTWDDVPGLGGSTVALRIGFSNKGKGHDAINLELHETAHAIDHIVLNDISKSA
                     QFKQIFAKEGRSLGNVNYLGVYAEEFFAESFAYYYLNQDTNSKLKSACPQTYSFLQNL
                     AK"
     gene            complement(17348..18310)
                     /locus_tag="PC512_002831"
     CDS             complement(17348..18310)
                     /locus_tag="PC512_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HDF2442564.1"
                     /translation="MKKGYVYIILTTLFFSSMEISLKTVTNDFNPLQITLSRFFVGGL
                     VLLPFAVKRLRALSLSITKSDLKYFAFLGFMCVVVSMSLYQLAVLNTKASVVAVLFSC
                     NPVFVMLLAYLILKEKIYRHNVISLILEVLGIIVIINPLHTKLTLSGIFLTLSSAIIF
                     SMYTVFGKRKTLKFGGIVVTCFSFIFGSLEMLILVLLTKINFIADILNKNKLHVFANI
                     PIFSGYTLHNMPIMIYVFVFVTGVGYALYFMAMEATSTSLTSLVFFFKPVISPILALL
                     ILKEIIPINMVIGILLIVIGSIISIIPTIITQMHNKHVEALYKE"
     gene            complement(18480..19670)
                     /locus_tag="PC512_002832"
     CDS             complement(18480..19670)
                     /locus_tag="PC512_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDF2442565.1"
                     /translation="MISNKMQTLVANSSVIRAMFEEGKKLSDIYGEENVFDFSIGNPS
                     VEPPETIKAVINDILNEESPNLVHGYMNNSGYEDVRDAIAEHINKKDGLNLTRENLIM
                     TCGAAGGLNIILKTLLNPGDEVIAFAPYFGEYKNYTENYDGKLIEVPTNIETFEPDLD
                     ALKNAITPKTRALIINTPNNPTGVIYSEELLKNLGELLDSKQKEFNTSIYLISDEPYR
                     EIIYDGAKVPCVLKYYRNSFIGYSYSKSLSLPGERIGYIVANGQMDDFDDVMSSLNVA
                     NRILGFVNAPSLFQRVIARSLDAEVDVNIYKKNFDLLYNSLIDMGYSCVKPNGTFYLF
                     PKAPIEDDKKFCNDAKQFNLLLVPGSSFGCPGHFRVSYCVSYDKVKSSLPAFEKLAKL
                     YNLK"
BASE COUNT         7771 a         2322 c         3379 g         6336 t
ORIGIN      
        1 taatagaagt aataaaaaaa aataattaat ataaaaatgt gtacaaacta atgaatattg
       61 atatagtaag ctatcatatg aaagagtatg tacacatttt ttttactaat ttttcacaat
      121 atgaacataa ataatttaca ggaaaggaat cttttatgaa aattcaaaat actgagtggg
      181 gatatattga atggaaacat acttatgatg aaaataatcc aaaacaagct atgaatatat
      241 acattgcagt aactatgcct ggtaagaaac attttaatca tgttcattat ggtcaagagc
      301 agatgatata tattttagag ggagagggtt tgtatattat aaatggagtt tggaagccat
      361 tttatcaagg tatgattttt tatatagaat ctggtagcac acatgaaact ataaatacag
      421 gcgatagaga aataaaagaa cttattgttt caaataatgt agatgatgta ggagagagtg
      481 aagttataga tattaatcct aataattatt taaagaagac cttgataaat tatagtgaaa
      541 gtacattaaa tttgtatgca gcagtagaat caattcgtgg tcaatttata gacccgttta
      601 aaattccatt aattatatat gatgattcat ggaatatagt tttaaaaaat ccttattttc
      661 cacttttttg ttttgaaaaa tgtaatccta tgaaatttcc tcaaaattgt gattgtatga
      721 atcaaaaaag tagcaatcaa tttgtatgtg aatatgggat aactatatat aatataccaa
      781 tactgtacaa aagcaatagc ataggtgtta taagaggagg gtatgtacta ttatctgatt
      841 tgaatttaga tacagagcat aataatttat atgatattcc agagggagct gctagaagta
      901 taaaacgcct cttgaaacaa atatctaaaa atataataaa tttttgctct tttaatgata
      961 taagaaagga tttacaagaa aaagagaaga ctatagcaag aacatatcat tatggagagc
     1021 aacttgaaat gaatttaaaa gtagctcaag atatggttac taatttaaga ataaatcatc
     1081 actttttatt taatacatta aattcaatgg caagcatagc actagatgat ggtagttatg
     1141 atttgtatag tgcaataata gatttatcaa gaatgtttag atatacaatg aggtctgatt
     1201 taagatttgt agaattagaa tctgaaatat tatacattaa aaattatttg aatttacaga
     1261 aattacgtta tggagatgca cttaaagtaa aatatcttat tccagagaag ttatataacc
     1321 tttctgtgcc ttttaacttt attcaaccta ttgtagagaa tgcatttaca catggattta
     1381 gagatattga cacagaaaag cgaattgaaa taattgcaag attagattct cagtatgcca
     1441 ttatagagat tcataataat ggaactatct tagatggaaa taatatagac aaaataaagg
     1501 caggtattcg tagtaataat ggtcatggtt tgtctttaat atatacaaaa ttcacatctg
     1561 cttatggaaa taattttgat atggatataa agtcgagtga taatgaagga acttacataa
     1621 tgattaaaat tcctattgaa aattataagg agtatgtata gaacttgtga aaaattaata
     1681 agttttataa atgttaagaa atatattaga tgtttttatg ttgttttata tatcttactt
     1741 ttttatatta ttaagctaaa agggaggtat tctcatgaga agagcactaa taatagatga
     1801 tgaagaagct gttctaaaaa taataacaca ttttatagaa atgaaagata tgccaataaa
     1861 aattgttggt aaagcaacat ctggtgatga agcagtagat aaaatcattg gtttagagcc
     1921 agacatagtt tttatagata ttcaaatgcc aatatacaac gggttagaag taatagaaaa
     1981 aacatctcat ttatctaaaa aaataaactt tgtagtaata actgcattta actattttga
     2041 atatgctcaa aaagctttga gattaaatgt aaaagatata ctccttaaac cattggatat
     2101 gaaagaattt actaagtctg tagaaaaaat tattggatat caatatacca ataatgattt
     2161 attaaatgag atactggaat atataaatct aaactatagc aatgacttaa agttaaatga
     2221 ttgtgctaga ttatttttaa ccaatccatc taatatatct aggattttta aaagtaattt
     2281 aaatacaact tttatatcat atctaaatca tataagaata gaaaaatcta ttgagttact
     2341 tgaaaatact acaaaaagta taaatgagat tgcagaaata gttggatata atagcctaaa
     2401 taacttttat aaaaacttta agatagaaaa aggaatgact ccaaaagttt ataaactgaa
     2461 cactaaaaat tgaaattgat aaataaaaag tcaatataga taattgtttg agtgtgtctg
     2521 aataagtata ctttaattat gataaaaatt aaagcgcttt aaacatattt aataatatta
     2581 aaccttataa aagctgtacc tatttatata aaaaaatata tataaataaa aagaaaaaga
     2641 tatacaaaat aaaaaaagtg aattaaatac tgtttcaaaa agacagaatt ttcatttaat
     2701 ttactgagag tttatatttc ttaaaggaag gtaactttat aatggaggta atttaatatg
     2761 tcagacaaag tgaatatgaa aaatattatc tgtattgcag gcgcttatct agcaacagca
     2821 attggttctg ggtttgctac tggtcaagaa attctacaat tttttgcctc acaagggtat
     2881 atgggtttaa ttggagcatt aatatcaatg gtattgtttt catttcttgg tgctgaagtt
     2941 ataactagag gtagagaatt aaaacttaaa gaaccaacaa gaatttacac tttttattgt
     3001 gggaagattt taggaaaatt ttacgaatgg tttagtccaa tatttttatt tgggattctt
     3061 atagtaatga tttcaggtgc aggctcaact ttaactgaat actatggtat aaatccttac
     3121 ttaggaagag tattgatggc tgttgctact ttaattacag tgtctatggg tttagaaaaa
     3181 ttagtaagca tacttggacg tattggacca gtgatagcag tatttacaat tgctgttgga
     3241 ttaataagct tgtttaagca ttttgacggt ttatctatgg ttggagaagc tatgaaaaat
     3301 attgaagtta caaaagcatc agaaagtcca atcgtttctg gtgtaatata taatacatta
     3361 aatattattg taatgattgt ttttttaaca ggaatgggag cttctattga aagtaaaaag
     3421 gatgcttttt ggggaggttt attaggtgga atagtgttta tgactgctgg tatagttatg
     3481 tatttggcta tgatttcaga tataggaaat ttgtatatga aagaaatacc atcactttat
     3541 ttagcagata atatatctcc gattgtaggt gtatgttttt cagttgcatt aatattaggt
     3601 atctatacaa cagctgttcc acttttatgg tctgtaacca atagaattgt tgaagatgaa
     3661 catcctaaat ttaaattggt aacaacagta atagctattt tggcttgtat aggaggtttt
     3721 ttaccgtttg gtaaattagt aaacatttta tatccatata caggttatat ggggctttta
     3781 attttagtct gtatggtgta taaagcaatt acatgtagaa aaaaatcaac acaaagtcag
     3841 gaatagagcc acttattaat agtttttatt taaaaaaatt ttttatataa tccgaattta
     3901 aaaagtcaaa atagttaaat aaattgcaaa acatgataat atatttaatt aaaataatat
     3961 agtaaaatat aaatataaac taaaattaaa tttataaaaa atatctttat aaagattatt
     4021 aacttatata atttgtagtt aaattataaa aaataaaaaa ataaaatttt ggagaggtgt
     4081 tagtatgcat gaacttattt taatctcaga aaagtataaa gaagatattt tagatttttt
     4141 tacagatatt catatgcacc ccgaattaag ttttaaagaa tttaggacta caaaagctat
     4201 aaaagattta ttagtgagtt tagacataga aatattagat ttaggaatgg aaacaggcgt
     4261 tgttggatta ttaaaaggga agtatgatgg tcccacagta gcactaagag gagatattga
     4321 tgcgttgcca atatatgaag aggttgatat taagtataaa tccagatatg atggtataat
     4381 gcatgcatgt gggcatgata tacacacgtc ttgccttgta ggatgtgcat atgtattgtc
     4441 tcatattaga gatagtcttc atggaaatgt aaagtttata tttcaaccag ccgaagaagt
     4501 caataaaggt gcgaagatgt tagtggaacg aggagtaatg gaaaatccaa aagttgatgc
     4561 tatatttgga cttcataatc atccagatat accttgtgga aaaataggtg ttaagttagg
     4621 tgggttaatg gcagcagtag acactattaa gatagaagta aatggatttg gaggtcacgg
     4681 aggtatacca aacagaacaa tagaccctat agtagcatca agtgcaatta taatgggtat
     4741 tcaaaccata gtaagcagaa acataagtcc attagaatca gctgttatat caataggtac
     4801 tataaatgga gggactgcaa ataatgtaat ttcagaaaag gtagatatga caggcacatg
     4861 tagaagcttt agtaatgaag tacgaaagaa aatatcagaa aatttagaaa atatagtttg
     4921 tgagatagct cgtggatatc aagcaactgc aaagctagat tatttatttg atttaccagc
     4981 tgttataaat agtaaagaga tgtacgcaat agcttgtaag tctgtgtgtg atttgtattc
     5041 agaagatgct atagttgatc caataccttc tacaggaggg gaagattttt ctatattcat
     5101 ggaaaaagcc ccaggatttt tttactggtt aggggtaggc aacaaagaac aagattgtat
     5161 atatcagtgg cataatccta aatttaaagc tgataaaaat tctatattgg taggtacaaa
     5221 tgtactatgt cagtctgtta taaattatat ggataaatta aaaaataaaa tttaagatag
     5281 agcattctgg agataaagtt tatgaggggg tattagtttg aggaaaatta attcacagga
     5341 aaaaaacaaa gatagtggat tattgatgag ggcactaaat gttgtagaga gagcaggaaa
     5401 taaacttcca gacccagtaa ccatattttt attactatgt ataattgttg taatattgtc
     5461 agcagttata tctaatttag gagtagaaga aatacatcct tctacaaaag aagttgtaaa
     5521 ggtagtaaat ctactagaga aagagcagat tcaatcatat ttaggtagca tagttacaaa
     5581 ctttcagtca tttgctcctt taggattagt actggttaca atgcttggag caggtgttgc
     5641 tgagaaatct ggatttatgg aagtgttaat gaaaaagggt ataagtaaag ttccacaaaa
     5701 acttgtaact gtagcaatcg tatttgcagg tatgttgtca catacagcag cagatgtagg
     5761 atttataata ttaccaccac ttgcagcact tgtgttttta ggaattggaa gacatcctct
     5821 tgtaggtatg tttgcagctt ttgcaggtgt tgcaggggga tttgcagcaa atgttatgct
     5881 tagtactaca gatgtattgt tagctggatt tacaatacca gcagctcaaa tgatggaccc
     5941 atcttaccaa ggcaatccag caatgaatct ttattttgct tttatatcag cgatagtttt
     6001 aacttttgca ggagcatttg taactgaaaa atttatagct cctcgtttta caaaatataa
     6061 tgattcaaca aatgataagg atatacagga attgagtgaa cttgaaaata agggtataaa
     6121 atacgcttta ttatcattgt tagttgtagt agtagtgata gttgccttat gtataggtga
     6181 caatgcattt atgaaagatc cagagactgg ttctatacta tctagtaatg cacctttaat
     6241 gaaaggtata gttcctataa tcactattat atttttaact ccaggattag tgtatggaaa
     6301 agtaagtaag aagataaaaa gtgacaaaga tttagtatct atgatgggta gtagtatgag
     6361 tgatatgggt ggatatatag tcctagcatt tatagcatcc cagtttatta atttatttaa
     6421 tcttagtaac ttaggaacaa ttttatcaat aacaggagca aaattactag cagagtcggg
     6481 aatacctagc tatggattga taataggatt tatattgcta tctggattta tcaatttatt
     6541 tgtaggaagt gcttctgcaa aatgggcgat tttagcacct atatttgttc ccatgtttat
     6601 gctactagac tttaatccag cattaactca aatagcttat cgtattggag atgcttcaac
     6661 aaatccaata agtccacttt ttccgtattt tccagttata ttggcctttg ccagaagata
     6721 tgataaagat ataggtatag gtactgtcat atcgaatatg attccatact cagtggtatt
     6781 tacattaata gaaataataa tattgttact attcatgggt attggcatac cattaggacc
     6841 tggtggagga atatcttacg ttttatagac cgttataata aatttatcaa tgaagattaa
     6901 actaataaaa tatattcttt aattaagagg aggattatta tgttaaaaac aacaaaaatt
     6961 tcagacccag agttatacaa gattgtagct gatgagttgg ttagacaaga acacaatatt
     7021 gagatgatag cttctgaaag tacagcacca acagaagtac ttgaattaag tggatgtgta
     7081 tttacaaata aaacagaaga aggctatcca ggggctcgtt ttcaagcagg ttctgaagaa
     7141 gcagataaac ttgaaaccct agcaataaaa cgtgcaaaag aagtatttgg agcagaacat
     7201 gtaaacgtac aaccgtattc aggttctaca gctaactatt gtgtatattc atcaatatta
     7261 aaaccaaatg acactgtttt aagtatgcgt cttgaccaag gtggacactt gacacatggt
     7321 agcgcagtta attttttaca tgacatttat aaatatgaat tttatggggt agacccaaat
     7381 actggacgta tagattatga tgctcttgaa gcaaaggcaa aagaatgtag accaaaactt
     7441 ataattgcag gggcaagttc atatccaaga ttaatagatt atgaaagaat atcaaaggtt
     7501 gcaaaagaag taggagctta ctttatggta gatatggcac atgttgcagg attagtcgca
     7561 gcgaaagtaa tacctagtcc tgtaccttat gcagattttg tttcttcatc tacgacaaag
     7621 actttctgtg gaccaagaag tggtattgta ctttgtaaag cagaacatgc aaagaaactc
     7681 gataaaggtg tttttccagg aacattaggg tctatacatc ttaatacagt tgcagcaaaa
     7741 gccttttcac tattatattt aagtacagat aaatttaaaa agataatgga gcaagttgta
     7801 gtaaatgctc agactctagc ttctgaactg atttcacatg gttttagtat tgtaagtgga
     7861 ggtactgata atcatatagt aatggttgac ttaagaagta agaatcttac aggaaaacaa
     7921 tttgaaaaag ctcttgaata tgtaggaata acagttaata aaaatgttat acctgacgac
     7981 ccacaatcac catttgtaac tagtggtgtt cgtataggtc ttacatcaat atctcaaaga
     8041 ggtctgaaag aaaaagaagt tatacagata gcagggataa tgaataaggt agcagaaaat
     8101 attgataata aagaagtatt agatgaatgt aaagcagagg cacaagaact tatatctaag
     8161 tttccattat atccagaagg gtattttgaa gattaaatat tttgatttgt atagctcaca
     8221 atttataaag cctgtaacat aaaatttaat aatatataac cactataagg tgttgattaa
     8281 tcaacacctt attttttttg aaaagtaata tacaagctat cataagcata taattcctta
     8341 tagataatta acaaggggga taaagttatg aggtattata ataaacctac caaagaagta
     8401 ttaaaatact taaaaacaaa tccagaaatt ggacttgatg ataatgaggt agaagaaagg
     8461 aagcttagat atggattaaa tgaatttact ataaaagaag gtagaacatt ttgggacgag
     8521 ttgggagaaa gtttgacaga acctatgata ttaattctca taggagcagc agtaataagt
     8581 tcttttgtgg gagaattaca tgacgcatta ggtattttag gggctatttt tattggaatt
     8641 tctataggca taataactga aggaaaatct aaaaaagcag ctcatgccct gtcaaaatta
     8701 acagaaaata tagaagtaaa ggtgcttaga aatgggaaga taattaaaat atcaaaaaat
     8761 gatttagtac caggagatat tgtatatata gaaactgggg atatgatacc agcagatgga
     8821 agacttatac agtctataaa tttgaaactt agagaagata tgctaacagg agaatctgat
     8881 gatgtagcta agaatgctga tgctgtatta gatatggaag tagtttattc taaaacagaa
     8941 ataatcgaac aggatgcaat acctgcaaag caagtcaata tggtatttgg agggactctt
     9001 gtagcatatg gtaggggcat aatggttgtc actcatactg gtgataagac agagatgggt
     9061 aagatagcac agaatttatc aaatgaagac cagcaaactc cacttcaaat taaattaggg
     9121 aagttgggtg ctaaaatagc gggaatatca ggcgtaatag ctactttatt atgtatgttt
     9181 atgattatac agatgcagag aaaaggtatg ttaattttag atacaagcag tgtattatct
     9241 ttcttacaat cattagaacc tgctaaaaat gcatatatgg tttgtattgc attaatagtt
     9301 gcaactgttc cagaaggttt gccaactatg ataaatatta ccttagctat aacaatgcaa
     9361 aagatggcaa agataaatgc attagtaaca aagaaagaag cctgtgaaac tataggttct
     9421 gtttctgtaa tatgttccga caaaacaggg actttaacac aaaacaaaat gatggtagag
     9481 gtagcatatg ttgatggtaa atatataagt ggaggagagt atcaaagtaa tagctatttt
     9541 gaacaaaact gtatagtaaa ttcaactgca gatatagaaa aagaagataa ttcatttaaa
     9601 tatataggaa gcgcaacaga gtgtgcatta cttttatatc ataatgataa gaactataat
     9661 gaaatgagaa aacaaacgta tttgatatca caaataccat ttagctcaga agaaaagaag
     9721 atgtcaacat taattcgtca agaggattca gatatattac tttcaaaagg tgctccagaa
     9781 gtattattaa aaaaatgttc ttatgtacaa caaggaaaaa atattgttcc aataactcca
     9841 aaagtagaaa aaagtatttt agatgagatt aagaagttac aaattaaatc tatgagaaca
     9901 ttaggatttg cttataaaaa aatgagtaat tctaaaacag aagttgcaat gacttcagaa
     9961 ggtgaattga atttaatagg aaattcaaga agttatatga aggaagataa tttagttttt
    10021 agtggatttg taggaatagt ggacccattg agagaagggg tcaaagattc cattgataaa
    10081 gcatttaatg caggagtaga tgtaaaaatg cttacaggag ataatataaa tacagcaaca
    10141 gctattggaa atgaattagg attattaaat gatgggaaaa aggcagttga agcaacatat
    10201 atagatgtat tgacagataa agaattgaga gaagaaatca aaggaatatc tattgttgca
    10261 agaagtaaac cagatacaaa aatgagaata gtttcagcac ttcaaaaaag tggcgaagtt
    10321 gtagctgtaa caggtgatgg tataaatgat gccccagcac ttagtcaagc agatgttgga
    10381 attgcaatgg gtatttcagg aacagaagta tctaaaaatg cagcagatat aatattgact
    10441 gatgatagct ttagtactat agtagaggga ataaaatggg gaagaggtat atatgagaac
    10501 tttcaaagat ttatacagtt tcagcttact gtaaatatag tagcatttat aattgctata
    10561 atatctcaac ttactggtaa ggatatgcca tttactacaa tacaattatt atgggtaaat
    10621 ataataatgg atggtcctcc agccctagca ttaggattag aacctgttag agattatgta
    10681 ttgaaaagaa aaccaataaa tagacattct ggaataatag ctaggtctat gtttgtaaat
    10741 attattataa atgctattct tataattaca attgtattta ctcaatcagc ttttaatata
    10801 ttgggagcta catcagaaga acaaggtact gttatatttt ctttatttgc attcagtgcc
    10861 ctttttaatg cattaaattg tagagagttt ggtttaaata gtacaatacc aaatttcttt
    10921 aaaaataaac tggcattgca aataatagta gttacaggga taattcaaat aatatttaca
    10981 caagtgttcc agagtttctt taattctgtt tctttggact ttgatatgtg gataaagata
    11041 atactatttg catccactat cctattgtca aatgaatttg taaagctaat tcttagaaca
    11101 atgaaaaata gtagaactat gaactttaat agtaaaaatt aattcctatg aaaccgcaaa
    11161 gtactatata ttgtaacttt gcggtttttg tttgtttaat gttgttttat attaccattt
    11221 tcatatttaa ttttttatta atctaaacac aatcttccat tgtaattgct tcatctgtgt
    11281 caacacattc aaagtcaata tctaattttt gtaatatttt gtatgcctct ttttgcaaag
    11341 gagtatcaaa ttcaataggt gattttgtgt aaatataact gataaaaaac atgatttatt
    11401 tcattccttt ccatttaaaa acttatagtt atagtgtatc ataaggttat aaaatataga
    11461 taaatatagt ataaatttaa aatatgtaca gacaaaacaa aaaaatcata ttctaagtaa
    11521 tacttgggaa aaatgatatt atcataataa ataatctttg taaaaactta tatagaatct
    11581 attaaacaga cactaagcca taaaaacttt actaaatata aaattcgtat ctaaatagat
    11641 atatagaata atattttact gaagtagagt gatttttaag aattttatat ataaattatg
    11701 ttatcataaa taaagatata gattataaaa tttgttaata aaataaaggg cagggaggta
    11761 agtttcatgt tttccaaaat cctagtcaaa acatttatca gagatagcga aaacgttcaa
    11821 aatacagatg ttagaaataa gtatggttat gtagctggtg tagtaggtat attatccaat
    11881 ttacttttat ttgtgataaa ggtattcata ggaatgctca catctagtat agctataatg
    11941 gctgatgcat ttaataatct ttctgatatg gcatcttcag caataactat gataggtttt
    12001 aaattagcaa gtaagccagc tgataaagaa cacccttttg gtcatggaag aatagagtat
    12061 ttatcagcat taatagtagc atttatggtg atgttggttg gacttcaatt tgtaaagtca
    12121 tctatagaaa ggatagtaaa tccaattcct gtaaaatttg aagtaatacc acttatactt
    12181 ttaattgcat ctataatgat taaaatctgg ttgagtcgtt ttaataaatt tatgggaaat
    12241 aaaattgatt cttcagcctt aaaagcagtt tcacttgatg ctttaggaga tgtatttact
    12301 tcaagctgtg tagttatatc atttattgta gctagattta ctaattttcc tatagatgga
    12361 tatgttggta tcgtagtatc attagtgata ctttatgctg gtttctctct tgtaaaagat
    12421 actataaatc ctcttttagg ggaagcacca gatgaagaaa tggtaaattc tattatagag
    12481 ctattgttat cttataaata tataataggt acacatgatt taattattca taactatgga
    12541 gttggtagat gtattgcatc tatacatgca gaaattccat ccaacataga tataatggaa
    12601 atacatgaaa ttatagatac tgcagagaga gaaatatctg aaaaattaga tatatatcta
    12661 gtaattcaca tggacccaat atgtcttgaa gataaagaag ttatgtcagc caaaaaagaa
    12721 cttgaagaaa tacttaagaa aaatagtctt gtaaaatcta tgcatgattt tagaatagtt
    12781 ggaaaaggaa gcaagaagaa tttaatattt gatatagtag ttaatccttc cgaattttcc
    12841 aaaaacatgt cagaagatga cttaaaagaa gatataacaa aattagttaa ggagataaat
    12901 cctgaatata attgtgtaat tgttgtagat aaggatttta tttaattatt aattaatctc
    12961 atcataaggt aaaaaatgta aaaaggatag acaatagtat agaggcataa tataatagaa
    13021 gtatataatt gtatttttaa tataaataaa gcaattttaa ttgtttttat gaaatattat
    13081 agagatgttg aagtatattc tattattggg caccttatgg atatactgag tcagtggtgc
    13141 aaccggctat gaatataaat ttatttattt tcatagcttt ttttgtataa ttttttagta
    13201 aaaattactt tatatacgat attaatggaa gattagatta taaattatag gtaacctaaa
    13261 ggggtgagat ttacatgaag aaaggaaata gaaaggcatt attaattagt ttaattatga
    13321 ttttaagtat ggtggtgtct acaatatatc caactgtatc ttatgcttca gaattaggag
    13381 agaatagtca gattcaaagt ggttcaacta attcatcaac tggagaggag aaggaaagcg
    13441 acaataaaaa gccagaacag actccagaga aagataaggc aacagataat aaaaaaccag
    13501 aacagacccc agaggaagaa aaaccaacag ataataaaaa accagaacag accccagaag
    13561 aagataagtc aacagataat aaaaagccag agcaaactcc agaaggagaa aagccaatag
    13621 ataataaaaa gccagagcag ataccagaag aagataagtc aacagataat aaaaagtcag
    13681 aacaagcttt agaagatgaa aaaccactag acaataaaaa tacagaaaaa actccagagg
    13741 aagataatct attagaagat gaaaatttat tgaaagtttt agaagaagaa cttaatgaag
    13801 aaaatgaaga ctatggattt gttgtaaaaa ttaataacaa tacaatagaa acggaatcaa
    13861 tgaaaaaaat atcatttaat ttaacttata ctccaacatc aaaaggaata caagcaggag
    13921 attcaataac ttttaaggtg ccagatgtat tcaataaagt taatttagat tatacaagtg
    13981 aatgctttga taaaacagaa agtaatggag agtatacact tacatttaga gaattaccta
    14041 atggccaaag tgtaatgcaa ggtaaaatag gtttggaagc atatgttaaa aaggttgatg
    14101 aagatactaa tgcaaaaata catattgaaa ctactggaaa aatagaaagt ggaagtggag
    14161 atatagatgt agaaataaaa cctggagata aaacggatgt tccagatgct aaaggaacac
    14221 ttaaaaagct tgttgaagga aaaaaatcaa ctactgtatt tatgccagtt aaaaataaag
    14281 atataaatta cagtatacaa gtaaatgaaa agcaggaaga gttaaaagat attattttgt
    14341 atgatgagct tcctgaagga ttgacattga taaatggttc tgtaagtgta gtaacaagtg
    14401 atggaaaaga agttagtgat tttaatattg aacagagtaa aaattctatt tcagttaatt
    14461 ttggaaatat agataaatcg tatactgtta agtataaggc tagaatcagt gacaaaaacg
    14521 caaaacatgg taataaatat aagaatgtag ctaggattga atctgatggt aagaagatac
    14581 aagaagatga tgctactgta agtatatttg atagaggaga tgattatctt cttactaaag
    14641 gacattcagg agcaacaaat attactcaag ttggtcaagt aataaactat cagatttcaa
    14701 taaatgatga taaatcacca ataagtaatg ttgttataac agataatata ccagaaggca
    14761 tgagattaac tacttcagga gaagctgggc atgattttag agttgtagaa attccaatga
    14821 atgggagctg gactccttgg agtaaagaaa aaattgccaa taatatttca tataaagtag
    14881 aagaaaaaag aaatgaaagt gggcaagtag ataaagttat aactggattt acaattaatc
    14941 tcagtaaaga agaagtggaa tcaaagtttt ttatagctta tacattaaag gtaattagta
    15001 ttgaagatag ctatataaat agagctgttc ttgatgcaaa taatagtgaa attgataaaa
    15061 atgatgagat aaactttaag aaaaattctg gattaataag cgcaaaaaaa gaagttgata
    15121 aaaaagtttt aaatagtagt gataaccaga ttgttaaata caaaatcaat atgtcaactt
    15181 atggagttta tgatgcagga caagtaaatc ttttagatga agtaaactca gctctagaaa
    15241 tatctaatat aaaatattct gataatcttg aacttaaaaa agaagctgga gatggaaaaa
    15301 atacaataag attagtaaat aaatacgaat ttaaacagat aaaagaaggg gaacctgtgc
    15361 aaagttgggt tacatttgat gcagacttca caaatgtaaa agttggggag actatacaaa
    15421 atgtggctca gattaatggt tcaagtcctc caggagtaga gactactaag caaggttatg
    15481 cttttgaagc taaaaaagtg gatgctttag ataaaaatgt actttcaggt gctaagttca
    15541 atttagaaga tgcatttgga aatatagtag ttaaggattt agttagtgat gaagatggta
    15601 taattcaatc tagtataaaa aaaccaggaa catattattt agtggagata atggctccaa
    15661 gtggatatga aaaactgaag gataaaatta aggttgaaat tggtaataaa gatattggta
    15721 gaatagtgga tattggaaat atagaaaaca taagacaaga aaatccacca gtaaatccac
    15781 cagcaccacc aaatacagat gaaccaatag taaatccacc agtaccacca agcacagata
    15841 aaccaaggaa accatcaagt tcatctgata cagaggatac tatagttata aatccaccaa
    15901 taccaccatc agaagatata ataaatccgc caataccaga ggtattgaat ccgccagtac
    15961 caccatcaga agagatgata gaaactcctg ttaaacagat tattccaata ccagaagtag
    16021 taaagccatc agtgtcagaa gaaaaaaata ataaagttaa agatgatact ttggtaaatc
    16081 caccagtacc accaaaaaca ggggatagta ctacaattat tggagaaata cttttggtta
    16141 taggagctat tgtaggactt atcgtattaa gaagaaataa aaatacaaat tagaccctaa
    16201 cattataaaa aatataagtt atattaaaaa atatcttcta aaacaatatt taataatgaa
    16261 aatattgtta gaagatattt ttttttgaag atttatgtaa aaaaataata actttttaga
    16321 aaaaagttcc aaagggatat agacaattaa aaagatataa gctataatat agatataaaa
    16381 ttaaatgagg caaaactagg gaaacctagt cacgcaaagc tataggggct aaagtttagt
    16441 aaaccatgcc agccagttgc cgaaaagagt aaaaatttct ttttgtatat acaaagatac
    16501 tcttgggtat cttttttatt ttgaaattta ttactcccgg cctaactcaa aggagggaat
    16561 aatatgagac caagtaaaaa attattaata gctataatat caatattctt aataagttca
    16621 gttccagtaa gtgcacatgc agatagtact actatacaac aaaataaaga cacacttagt
    16681 caaatagtag tttttccaac tggaaattac gataaaaacg aagctaatgc tatggtaaat
    16741 agattagcta atatagatgg aaagtattta aatgcattaa agcaaaataa cttaaaaata
    16801 aaattattaa gtggaaagtt aacagatgaa aaagaatatg cttatttaaa aggtgtagtt
    16861 cctaagggat gggaaggtac tggaaaaact tgggatgatg ttccaggttt aggtggaagt
    16921 acagtagctc ttagaatagg atttagtaac aaaggtaaag ggcatgatgc aataaattta
    16981 gaattacatg aaacagcaca tgcaatagac catatagtat taaatgatat atctaaatca
    17041 gcacaattca aacaaatatt tgctaaagaa ggtcgttctt taggtaatgt aaactactta
    17101 ggtgtatatg cagaagaatt ttttgcagaa tcatttgcat attactattt aaatcaagat
    17161 acaaatagta agttaaaatc agcttgtcca caaacttata gctttttgca aaatttagct
    17221 aaatagagtt ttaataaatt taaaataaat ataaataaag agatgctatt ataatagcat
    17281 ctcttttata ttgcgtttaa atctaataaa ttttgtctta tgtataacta tgatagatta
    17341 tcaattacta ctccttatac aaggcttcaa cgtgtttatt atgcatttga gtaattatcg
    17401 taggtataat agaaattatt gaaccaatta ctatcaataa aattcctata accatgttta
    17461 tagggataat ttctttaagt attaataatg ctagtattgg agatattact ggtttaaaga
    17521 agaatactaa agatgtaaga ctagtagatg tagcttccat tgccataaag taaagcgcat
    17581 aaccaacacc tgtaacaaat acgaatacat aaatcataat gggcatattg tgtaaggtat
    17641 atccactaaa aatagggata tttgcaaata catgaagctt atttttattt aatatatctg
    17701 cgataaaatt aattttagtg agtaaaacca atatcaacat ttccaaacta ccaaatataa
    17761 agctaaagca ggttacaact attccaccaa attttaaggt ttttctttta ccaaatacag
    17821 tatacattga aaaaataata gcagaagata atgttaagaa tattccacta agagttagtt
    17881 ttgtatgcaa tggatttatt ataactataa ttccaagaac ttctaatata agtgaaatta
    17941 cattgtgcct atatattttt tccttcaaaa ttaagtaagc taaaagcatt acaaagactg
    18001 gattacaact gaacaaaaca gcaactacag atgcctttgt gtttagaaca gcaagttgat
    18061 acaatgacat acttactact acacacataa aacctaaaaa tgcaaagtat tttaagtctg
    18121 attttgtaat agaaagacta agagctctta atctttttac agcaaaaggt agtaagacta
    18181 aaccgccaac aaaaaatctt gataaagtta tttgtaaggg attaaagtca ttagtgacag
    18241 tttttagact aatttccatt gaactaaaaa ataaggtagt cagtattata taaacataac
    18301 cttttttcaa gtcaaacacc tccttgtaat ttatattagt actatagata agaatattca
    18361 agcatattgg aataatatgg tatgtataaa atatagtaca taaaattata aactacctta
    18421 atatagaatg taagtattct atactaaggt agttaattat ttgaattact ttgatttagt
    18481 tattttaaat tatataattt ggctaatttt tcaaatgctg gtaaagaact tttaacttta
    18541 tcataagata cacaatatga tactctaaaa tgacctggac aaccaaaaga agaacctggt
    18601 actaataata aattaaattg ttttgcatca ttgcagaatt ttttatcatc ttcaattgga
    18661 gcttttggga acaaatagaa tgtaccatta ggtttaacac aagaatatcc catatcgatt
    18721 aaactattat atagaaggtc aaaattcttt ttataaatat ttacatcaac ttctgcatct
    18781 aaacttcttg caataaccct ttgaaaaaga gaaggagcat ttacaaatcc aagtattcta
    18841 tttgcaacat ttaatgaaga cataacatca tcaaaatcat ccatttgccc attagcaaca
    18901 atatatccta tacgttcacc aggtagagat aatgatttac tataagagta tcctataaat
    18961 gaatttctat agtattttag tacacaagga actttggcac catcataaat tatttctcta
    19021 tatggctcat cagaaattag gtatatgctt gtattaaatt ctttttgttt tgaatccaat
    19081 aattctccaa gattttttaa taattcttca gaatatatga caccagtagg attatttgga
    19141 gtgtttatta ttaaagctct tgtttttgga gtaatagcat tttttagagc atctaaatct
    19201 ggctcaaaag tctctatatt tgtaggaact tctattaatt ttccatcata gttttctgta
    19261 taatttttat actcaccaaa atacggtgca aaagcaataa cttcatcacc aggatttaaa
    19321 agagttttta aaataatatt tagaccacca gcagcaccac aagtcataat taaattttct
    19381 cttgtaagat ttaatccatc ttttttattt atgtgttcag caatagcatc tcttacatcc
    19441 tcatatcctg agttgttcat atatccatga actaaatttg gagattcttc atttaaaata
    19501 tcatttataa ctgctttaat agtctctgga ggttcaacac ttggatttcc tatactaaaa
    19561 tcaaaaacat tttcctcacc ataaatatca gaaagtttct ttccttcttc aaacatagct
    19621 cttataacag aactatttgc aactaaagtt tgcattttat tagatatcat atgtaacact
    19681 cctttttata gatttatatt gcttatgtat atattaccat atttttactg aatttagaca
    19741 attttcgaaa aattacttgt ttgaaaatat aaacttttat ataaaatata tttatgtaca
    19801 gtacatat
//
LOCUS       DAMJVG010000073        19750 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.073, whole genome shotgun sequence.
ACCESSION   DAMJVG010000073 DAMJVG010000000
VERSION     DAMJVG010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19750)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19750)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19750
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.073"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(480..1352)
                     /locus_tag="PC512_002833"
     CDS             complement(480..1352)
                     /locus_tag="PC512_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF2442566.1"
                     /translation="MEETNEMKDSKHLISNIQSQYTRLSKGQKLIAQYILNNYDKVAF
                     MTACKLGETVGVSESTVVRFANALGYSGYPKLQAALQELIKNKLTTVQRVEMAHDYSD
                     DFAILNKVLKSDIDNIRSTLEEIDERAFKEASNKLLRARKIYILGMRSSFVVAQYLGF
                     YLDIILDNVHIIRMDMGDAFEQIVRINEEDVIVAISFPRYSKKSYQIVNYAKEKGAHV
                     ISLTDSLFAPVASLADNTLLVKSNMASFVDSLVPALSISNALAISVGMKEKEDIKQHF
                     DDLEQIWKRYSVYE"
     gene            complement(1746..2324)
                     /locus_tag="PC512_002834"
     CDS             complement(1746..2324)
                     /locus_tag="PC512_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDF2442567.1"
                     /translation="MAYAKYLTKITDINKFYLENIINEGDIVIDATMGNGYDTRYLAE
                     KVGEKGFVYAFDIQEEAIKSTRKKLEKEGYTDRVKLIFDGHEKMNQYIKEEVSCVLFN
                     LGYLPRAKHSIITKPDTTLKAIKLSLEMLKENGVISIAIYTGHDGGQEEKDCIYNLVN
                     NLNQDEFNVLESKFLNQVNNPPQLILIEKKKA"
     gene            complement(2382..3098)
                     /locus_tag="PC512_002835"
     CDS             complement(2382..3098)
                     /locus_tag="PC512_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HDF2442568.1"
                     /translation="MRINKYIASCGIASRRKAEEIILGGRIKVNGSVVKELSFNIDEE
                     KDIVEFDNKKVKPSENYIYIVLNKPEGYITTVKDQFNRPSVIDILKDVRERVYPIGRL
                     DYETSGLLILTNDGDLTYKLTHPKHEIDKMYVASVKGIISDDEIRQFETGLKIEDYTT
                     APAKIRVTKENKEKNYSVCEITIHEGRNRQVRKMCKAINHPVLNLRRISVGKIVLKDT
                     KVGEYRYLTEDEIKYLKSIK"
     gene            3289..4374
                     /locus_tag="PC512_002836"
     CDS             3289..4374
                     /locus_tag="PC512_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDF2442569.1"
                     /translation="MIIISKENIKYYLIVVFIGILFFKFINTPSDFISSIEGFLKFFS
                     PFLLAILLALLLNPLVMLFEIKFKAHRLLAIFLSYIFIGFILAFAIRLLIPSIANTLN
                     RLINEMPMYTDYIDSFIEKNMSNIYFLKTLIPHIQHSLDNLLKEASNFVGKIPKNFLI
                     YTLSISSMLFNMTMGFILSIYIIYDKEKIALGFKRFLYSSTARNKADNIIEFFRTTHD
                     IFYDYLLGRILDSLIIGIIAFLGFQFVIRIENALFLASIIFLGNIIPYFGPFIGAIPP
                     IAMTILYSPQKTIWVIAFLFILQQLDGNFIEPKVMGNQVGIGAIWVISAILVGQSLFG
                     FIGVFLSVPIAAVVKTYVDKYIDNRLQ"
     gene            complement(4529..5188)
                     /locus_tag="PC512_002837"
     CDS             complement(4529..5188)
                     /locus_tag="PC512_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442570.1"
                     /translation="MRGRVILLISILSIFLVGCSFNKKDEINLVEQGKTYLEKHNYKK
                     AMESLSSALEEDSTNENARAMYMQAMRMSNMTEFEELKNYEGAIKELKLIEKIKNGSS
                     VIKEEATKKKEELTKLEKEQNEAEEQRKKKAKDTAGEDRYRVESDARKSSYSGSSKNN
                     KSSSKNNDKKSDSNKSDNSNSSSQNQEKPNNSNPTPAPTPQDTTGGSDSGGNSQNSNN
                     Q"
     gene            complement(5405..6697)
                     /gene="lysA"
                     /locus_tag="PC512_002838"
     CDS             complement(5405..6697)
                     /gene="lysA"
                     /locus_tag="PC512_002838"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HDF2442571.1"
                     /translation="MKLHGTMTVNNDELYIGGVSCLELSKKYQTPLYVFDEALVRQNC
                     REYVEYFKAREGKNKVAYAGKAFLPLYMCNLINEEQMCLDVVSGGELYTAYKSNFPME
                     KVFFHGNNKTKEEINMGLDLGVGKFVVDNFYELDLLEALCEDKGKTQEIYFRITPGIE
                     AHTHDYIKTGQIDSKFGFALVNGDLFRAIEKLSEYKNIKLVGLHAHIGSQIFDVEPYI
                     DTVDIMMNLVKEIKEKFNIQLTEIDLGGGVGVYYSEGDKPKTIKEFCETIITKAETSC
                     KELGIEVPTLVIEPGRSIVANAGSTLYTVGSIKDIKDVRVYVSVDGGMTDNVRPSLYQ
                     ASYECSIVNKINHEAMNHVTIAGKCCESGDILIGDINIMDIKSGDILITTSTGAYGYS
                     MSSNYNKIPRAAVVSVFDGNDKIICKRQSYEDLLALEI"
     gene            complement(6715..7908)
                     /locus_tag="PC512_002839"
     CDS             complement(6715..7908)
                     /locus_tag="PC512_002839"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HDF2442572.1"
                     /translation="MSIIVQKYGGSSVADTEKIKSIAENIIERRKENPQMVIVVSAMG
                     KSTDEYITLAKELSNEPSKRELDALMSTGEMISASLLSIALNALGCKAISYNAYQLNI
                     KTSGLHGKSQIDDINVNRIKNSLDEGNVVIVTGFQGINEDGDVTTLGRGGSDTSAVAL
                     AVKLNGKCEIYTDVDGIYFTDPRKYSKASKLDEIEYEEMLELASLGAQVMHSRSIELA
                     QKYGVEIYVGRTCGTEKGTYIRGGKDMKLEDKVITGLATSDDDSSITIKDFKAENISS
                     LFEDIATIGISVDMISQTAPILDKISVSFTVPKEELGECKKIVSKYTDEEHVVIDNNI
                     TKFSLVGLGMKNTSGVAAKVFKIFNENGIMIKLITTSEIRITCAINSDDKQVAIEKIA
                     EVFNI"
     gene            complement(8269..8886)
                     /locus_tag="PC512_002840"
     CDS             complement(8269..8886)
                     /locus_tag="PC512_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442573.1"
                     /translation="MTNMEKEILLLISRVRCVTESQFRKIYGDQKRYNKKNFKKTLRK
                     MCSEYTLKKYPCDVDYYNYKDLSYVYYLNGSKLFKGDDLIKALVGSELVVRINTAGCD
                     VKRFYRNVSVDDVKYDLFIEYTDQFGNIKQVLVDVDLNNEIDISKYENLSKKIDKSTI
                     PFFKVPNVLVVTPDNLSELNDLERYDNEYSINFIDLGLNKLFNCI"
     gene            complement(9056..10756)
                     /locus_tag="PC512_002841"
     CDS             complement(9056..10756)
                     /locus_tag="PC512_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442574.1"
                     /translation="MKRYLKTYGVALIIVIIYAFIKLPVLRLDFTSLFSVGIIFFVVA
                     GILDMMLDRNERASKMAKYNFSIAIALLVYIVVVPFITSTPVLHAKSYRELLGKVTES
                     KFTDDISPVSVNDIRLVDEDMAMKLGDKKLGEVPAIGSVSKLGKFHIQNVDGELYWVA
                     PLVHRDIIKWITSLSGTSGYVKVSASNPQDVQLVQEIDGKPIKIVYQPEAYLHQDLQR
                     HLYIHGIVNVGMTDFTLEINDEGRPYWVVSLYEHKIGYGGANATGIATVDAETGKINV
                     YDVKNTPKWVDRIQPQSFVTDQIKDWGVYVNGFLNSVISEKGVLVPTEGTSLVYGNDN
                     RSYWYTGITSSGGDESTIGFMLVDSRTKEARLYKQPGATETAAMKSAEGNVQEKNYEA
                     TFPVMYNILGQPTYVSSLKDKAGLVKRVAFVSVEDYNVLGIGEDKNEALRNYKDALES
                     KGNDLKLDNDLKDEVLEGTVTRISPDVRGGNTNYYVTLDSNKDIIFRATSKVSSELPL
                     TQVGDKVKISYSKEESGVIEMSEFDNLNIANFEDKKAKEKTGTDENTDSKDSENQGNV
                     "
     gene            complement(11153..11716)
                     /locus_tag="PC512_002842"
     CDS             complement(11153..11716)
                     /locus_tag="PC512_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442575.1"
                     /translation="MNKVYIVTTYTGTILSYLIRNISKKLYTHVSISLNENLKPMYSF
                     GRLNPRNPFIGGFVEENINQGLYAIRKNTVCRVYSLEVDNLQYENLYKNIKLISDYRE
                     DYYYDTMALIYLLMNIQRQSEYKYVCSNFVADMLEKSEIDILNKQAFEVTPNDFYNLS
                     GLTLEYEGLLSEYNSRQHSYVSKIANI"
     gene            complement(11875..12588)
                     /locus_tag="PC512_002843"
     CDS             complement(11875..12588)
                     /locus_tag="PC512_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2140 domain-containing protein"
                     /protein_id="HDF2442576.1"
                     /translation="MGKVAKILLSLIVIVLVLVGIVVYILTPKERYDVSSQNNKIIDE
                     EYLSKGSYINSMEVVKNPLRMVGKISVSEEEFKNLIYTLMQKHGINELENNFVEMKNG
                     KIKVAGPYKVFGLVNSQYELELRPTLKDGNLVVSLENVKIGKFKLSDKMLEKILSNYN
                     KKVPFEVNGNKITLEKSYLYPITLKNISIKKGNVDLDMEVEIDLKSQINGALGYLKDS
                     GKVQDILNHLINLKKTSVG"
     gene            12880..14544
                     /locus_tag="PC512_002844"
     CDS             12880..14544
                     /locus_tag="PC512_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--tRNA ligase/YqeY domain fusion
                     protein"
                     /protein_id="HDF2442577.1"
                     /translation="MSNETNSSNFIKNIIINDLETGKHDSIITRFPPEPNGYLHIGHA
                     KSICLNFGLAKEFNGKANLRFDDTNPLKEDVEYVESIKEDVKWLGFDWNELNFASNYF
                     DEMYKRALILIKKGKAYVCDLTQEEMREYRGTLTEPGKESPHRNRTIEENLDLFERMK
                     NGEFKDGEKTLRAKIDMSSPNINLRDPIIYRISHSTHHNTGDKWCIYPMYAFAHPIED
                     AIEGITHSICTLEFEDQRPLYDWFVKECEMENIPRQIEFARLNINNTVMSKRKLKQLV
                     DEGIVDGWDDPRVPTISGIRRKGYTAEALRNFCSEIGVSKVNSTVDSQMLDYFLRENL
                     QPKAPLTMGVLRPLKLIITNYPEDKIEMLEIENNAKDESQGKRLVPFSRELYIEQDDF
                     MEEPVKKYFRFFPGNEVRLKGAYFVKCTDVIKDENGNVVEIHGTYDPETKSGSGFTGR
                     KVKSTIHWVDAKSAIPCEFRLFEPLILDDIPENEGKHFLEQINPNSLEILQGFVEPTQ
                     IKDAKPFDKFQFVRNGFFSIDNKYTTDEKFVFNRIVPLKSSFKPGK"
     gene            complement(14651..15550)
                     /locus_tag="PC512_002845"
     CDS             complement(14651..15550)
                     /locus_tag="PC512_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HDF2442578.1"
                     /translation="MKKVKLIYNPNSGEKKILSNLDTIIELYQEKNYLLIPYRLTIKE
                     PVKNAFKEVDSSYEHILIAGGDGTVDLVVNAMKELDIKIPIGILPTGTANDFSNALQI
                     SFDIKEAINEIINSKPKKIDIGKVNNKYFINVASAGMFTDVSQRINTDLKNSFGRISY
                     YIKGIEEALYMRKFKIKVSSEEMYYDGDMYLMLIFNGKTAGNINLAYKAEIDDGYLDV
                     IIFKGMPIPKSIPVLISVLRGDYLDQYNGNEILYFKTKKVHIECEDSLITDIDGEKGP
                     DFPLNIECIKDGIEVMGICSEKS"
     gene            complement(15577..16215)
                     /locus_tag="PC512_002846"
     CDS             complement(15577..16215)
                     /locus_tag="PC512_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003356606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein"
                     /protein_id="HDF2442579.1"
                     /translation="MDQNLNWLNEKRIEKTIKSLENNNMKGYLVSNKEELLKKIEEIV
                     KAGSLVGCGGSMTLFETGVIDFIREKYNFLDRYAKDIKPEEMKEIYRKSFSADAYFTS
                     TNAITEDGELYNLDGNGNRVAAMIYGPDKVIVIAGVNKIVKDVDEAIKRTKTIAAPAN
                     CKRLSTNTGCKTTGICIDCSSPGRICCSYTLIKRQLTPERIHVIFLNEDFGY"
     gene            complement(16552..17550)
                     /locus_tag="PC512_002847"
     CDS             complement(16552..17550)
                     /locus_tag="PC512_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4003 domain-containing protein"
                     /protein_id="HDF2442580.1"
                     /translation="MEQSFINGKVNLLIENYKALNEVKGSWQMGLIQHSCALAFTLKN
                     KKISPRLVEERIELIKKNTGLFSNFRGYNMFYMATLLSFESNPESSFKMILDIYKELK
                     SEKFWGDTYLPLTASIVYENREKMDYLTCISKMKIIYDYMRKKHPFLTSSDDYCNIAL
                     IAIHSKNLDEDLEYIEKCYEFLNENGFYKGNDLQALSQILLFSDDRTMLKCKKTIELK
                     KAFKENDCKMNYYGYPIIGAISLLDYREDEIIEEIKNVSNKLKEEKGFGNWSLGKSNR
                     VMISSAIVASIYADLIRNENNIGSITNNIFLNIVVAIQIACVMAATSAAIASSSSN"
     gene            complement(17648..18223)
                     /locus_tag="PC512_002848"
     CDS             complement(17648..18223)
                     /locus_tag="PC512_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442581.1"
                     /translation="MKLKEALITCVVCSVCLTPLLVNGETKIDADHCKESIVNIDTIV
                     KSGKSFNSKYNQGMEDYKNSDEYKLKVQKEKLQNQLGIKIKKLVPITFEVSYYTSLNQ
                     ENGYGAITATGDDLEDGFVANNHLSFGTKIIVDGKLKTVMDRGSSKYFSNSNAIDVFV
                     PKWSNESESEYYDRVNNMGRHYKKGYIIVEE"
     gene            18539..18802
                     /locus_tag="PC512_002849"
     CDS             18539..18802
                     /locus_tag="PC512_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442582.1"
                     /translation="MIKNTKQITVEVNEILLQEMSKITNYENNILTDLINESIVNYIL
                     ENKKHNIENKDLEEVIKFYKKENTEKPKSAARAIAEAKTHTLY"
     gene            complement(19239..19616)
                     /locus_tag="PC512_002850"
     CDS             complement(19239..19616)
                     /locus_tag="PC512_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2442583.1"
                     /translation="MTITKIPPAELKVMKFIWSSDFTVASKDVIEAMEKLYNWKQTTT
                     LTLLSRLVNKQFLSARKIDRHTHYTVLIGEEEYLHFETKTFLDNMHGSSIESFMKSLF
                     KKGVNEEELNSVEKWVKDIKKDE"
BASE COUNT         6511 a         3230 c         2054 g         7955 t
ORIGIN      
        1 taaagtatta tatttctaaa aaagtttccc tttccccaaa aatggctact taaaaaatca
       61 agatttcata cctaactact aattctatga tttttaaatt tttcaacttc tttgtcaaag
      121 ttaaaataaa atactaaaag acacatatta tagtgaacaa aaaagataga aatacatatt
      181 ttaatagaat tttaataaga tattatatac ttaaatacaa ataaaattaa ttttataatt
      241 gttaattaag gaaatgatat tgtttagaga aataaaaaaa gcactctcca tgaagggaaa
      301 tgctttcttt aataaattag ttgatgtagt aaagatatat tcagaataca tctttatgtt
      361 ttgagtctcg aaatatttat ttgtattatt taaacgaaaa tttatttttt aagtgataat
      421 ctagtattta ttaataaggc tatgattctc aatttcatag ccttattaat acacaaactt
      481 tactcataca cagaatatct tttccaaatt tgctctaaat catcaaaatg ctgtttaata
      541 tcttcttttt ccttcatccc aacagatata gcaagagcat ttgaaatact aagagctgga
      601 actagagaat ctacaaatga agccatatta ctcttaacta gaagagtgtt atctgcaagt
      661 gatgctactg gcgcaaataa gctatctgtt aatgatatta catgggctcc tttttcttta
      721 gcataattga caatttgata agatttctta gaataacgag ggaaactaat agcaactatt
      781 acatcttctt catttattct tacaatctgc tcaaaagcat ctcccatatc cattctaatt
      841 atatgaacat tgtcaagtat tatatctaag taaaaaccta aatattgagc tactacaaaa
      901 gaactcctca ttccaagtat atatattttt ctcgctctta aaagtttgtt agaagcttct
      961 ttaaacgctc tctcgtcaat ttcttctagt gtagacctta tattatctat atcacttttt
     1021 aaaactttgt ttagtattgc aaaatcatcg gaataatcat gtgccatttc aactctttgt
     1081 actgtagtta gtttattttt tatgagttct tgaagtgcag cttgtaattt aggatatcca
     1141 ctataaccta atgcatttgc aaatcttaca actgtagact cacttactcc tacagtttca
     1201 cccaatttac atgcagtcat aaatgcaact ttatcataat tatttaaaat gtattgtgct
     1261 ataagttttt gacccttact caatctcgta tattgagatt gtatatttga tatcaaatgt
     1321 ttactgtcct tcatttcatt tgtttcttcc atttttttct ccttttagtt atataaacta
     1381 ttttgtttta ttaacactgt ctttttctct aaaaatttta ttttttatct caatttcatc
     1441 ttagttttta tcatagcttc ttaaactcat aaaattctaa cttttctgta ccttatactt
     1501 cacatagtat tttcgattaa atttattata ccatctttcc ttgcattttt taatatttat
     1561 ccaatatttc ttttaaattt ttcaattttt actcatttaa aagttatcta tcttattttg
     1621 catatttaga tgtatatttt gttttgagaa taaactgttg tatacttatt atttaaagta
     1681 tttttaatag gtcacactat atatattaac tcttaataca atcttgtcaa gttttttagt
     1741 atttattatg cttttttctt ttcaattaaa atcaattgtg gtgggttatt gacttgattt
     1801 aaaaacttag attctaaaac attaaattca tcttgattta aattattgac aaggttatat
     1861 atgcaatctt tttcttcttg acctccatca tgccctgtat atatggcaat gcttattact
     1921 ccattttctt ttaacatttc taaacttaac tttatagcct ttaaagttgt atctggtttg
     1981 gttataattg aatgtttcgc tcttggaaga taacccaaat taaataaaac acatgaaact
     2041 tcttctttta tatattgatt cattttttca tgcccatcaa atatcaattt tactctatct
     2101 gtatatcctt ctttctctag tttctttctt gtagacttta ttgcttcttc ttgtatatca
     2161 aaagcatata caaagccctt ttctccaacc ttctcagcta gataccttgt atcataccca
     2221 tttcccatag tagcatcaat tactatgtca ccttcattta taatattttc taaataaaat
     2281 ttatttatat ctgtaatttt agttaaatac tttgcatatg ccataatact atttctccct
     2341 actattaact ttatttcatt ttttctcaat ttatttttat cttattttat tgattttaaa
     2401 tattttattt catcttctgt taggtatcta tattctccaa ctttggtgtc ttttaatact
     2461 attttcccca cagaaatcct tcttaaattt aaaactggat gatttatagc tttgcacatt
     2521 tttcttactt gtctatttct accctcatgt atagttattt cacacactga ataatttttt
     2581 tctttatttt ctttagttac ccttattttg gcaggtgccg ttgtgtaatc ttctattttt
     2641 agtcctgttt cgaattgtct tatctcatca tcacttataa ttcccttcac acttgccaca
     2701 tacattttat caatttcatg ctttggatgg gtaagcttat atgttaaatc gccatcatta
     2761 gtaagtatta ataaaccact agtttcataa tctaatctcc ctattggata tactctttcc
     2821 cttacatctt taagtatgtc tattacactg ggtctattga attggtcttt tactgtagtt
     2881 atatatccct ctggtttatt taatactata tatatataat tttcacttgg ttttactttt
     2941 ttattatcaa attctactat gtctttttct tcatcaatat taaaagataa ctcttttact
     3001 acacttccat ttacctttat tcttcctcca agaattattt cttctgcttt tcttcttgat
     3061 gctattccac aagaagctat atacttatta attctcatac ttaatccttc cttatcttaa
     3121 attatgtgtg tttaatattt ttatcaatgt taattttgct acattattat actatactag
     3181 accttaatta aaaacaagca aaaaaattat ttaattttcc taaataattg taatttcttt
     3241 tcacatacta ttaatatgta atagctgact aaacactatt ttaaggaagt gattattatt
     3301 tcaaaggaaa atataaaata ttatttaata gtcgtgttta ttggaatttt attttttaaa
     3361 tttattaata ctccatcaga ctttatatct agtattgaag gattcttaaa gttttttagc
     3421 ccatttttat tagctatttt acttgcttta cttttaaatc cacttgtgat gctttttgag
     3481 ataaaattca aagcacatag acttttagcc atttttttat cttatatatt tataggtttt
     3541 attttagcct ttgccattag gttattaatt ccatcaatag ctaatacatt aaatagattg
     3601 ataaatgaaa tgcctatgta tactgattat atagatagtt ttatagaaaa aaatatgtca
     3661 aacatatatt ttctaaaaac tttaattcct catatacaac atagtttaga taatttatta
     3721 aaagaagcaa gtaattttgt tggtaaaatt cctaaaaact tcttaatcta tacacttagt
     3781 atatcttcta tgctatttaa tatgacaatg ggatttatac tatctatata cattatatat
     3841 gacaaagaaa aaattgcatt gggatttaag agatttctat attcttctac tgctagaaac
     3901 aaggcagata acattataga attttttagg actactcatg atattttcta tgattattta
     3961 cttggtagaa tattagactc tcttattatt ggtataattg catttttagg atttcaattt
     4021 gttatcagaa tagaaaatgc tttattttta gcttcaataa tattcttagg taatataatt
     4081 ccctattttg gtccttttat tggtgcaatc cctccaatag ccatgactat attatatagt
     4141 ccacaaaaaa ctatatgggt cattgcattt ctatttatat tgcaacaatt agatggaaat
     4201 tttatagaac caaaagttat gggtaatcaa gttggtatag gagctatatg ggtaatatct
     4261 gctattttgg tgggacaatc tctatttggt ttcataggag tttttctttc agtaccaata
     4321 gctgctgttg taaaaactta tgttgataaa tatatagata atcgtttaca atagcttatc
     4381 tctactgtga ctttaatttt tagtttaaaa tttaactgtt atttattaaa ttatttctca
     4441 aaaaatatct cttagtaaga aaaaattgct aagagatatt ttttataata tataatttgt
     4501 tcattaaatt tatgcatata ttttatactt attgattatt tgagttttga gaatttccac
     4561 cactatctga accaccagta gtatcttgtg gagttggtgc tggtgttgga ttactattat
     4621 ttggcttttc ttgattttga gaagaactgt tactattgtc agacttatta ctatctgatt
     4681 ttttatcatt atttttagaa ctagatttat tatttttact acttccacta taagaagatt
     4741 tccttgcatc tgattcaact ctatacctat cttctccagc cgtatctttt gcctttttct
     4801 ttctttgttc ctctgcttcg ttttgttctt tttctaattt agttaactct tctttctttt
     4861 tagttgcctc ttctttaata acagaggaac catttttgat tttctctata agtttaagtt
     4921 ccttgattgc accctcataa ttttttaatt cttcaaactc cgtcatattt gacattctca
     4981 tagcttgcat atacatagct cttgcattct cattagtact atcttcttcc agtgcagagg
     5041 ataatgattc catagctttt ttatagttat gtttttctaa atatgttttt ccttgctcta
     5101 ctaaatttat ttcatctttt ttattaaatg aacatcctac aagaaatata gataatatcg
     5161 atattaataa aattactctt cctctcatta aatccctcct tgtcatatac tttaaatttt
     5221 atcataatta taaagttttt aaaatatttt atatttatta caagaaattt gttagtaaaa
     5281 caaaaaataa gcagatatgc tacgaacgat acaataaacc aaaaattaat ttagagatac
     5341 atatcctagc aaatctgctc ataataaact ttaatattta atttttatta tatacttctc
     5401 cattttatat ctctaaagct aataagtcct catagctttg tctcttacaa attatcttat
     5461 catttccatc aaatactgat actactgctg ctcttggtat tttattataa tttgaagaca
     5521 ttgaatatcc atatgcacca gttgatgttg ttataagtat atctccactt ttaatatcca
     5581 ttatgtttat atctccaatt aatatatctc cactctcaca acattttcca gctattgtta
     5641 catgattcat agcctcatga ttaattttat tcacaatact acactcataa ctagcttggt
     5701 acaacgaagg tcttacatta tctgtcatac ctccatctac acttacataa accctaacat
     5761 cttttatatc ttttatagaa cctactgtat acaatgtact tcctgcattt gcaactattg
     5821 accttcctgg ttctattacc aatgtaggta cttctattcc aagctcttta catgaagttt
     5881 ctgctttagt gattatggtt tcacaaaact cttttatagt tttaggttta tctccttcgc
     5941 tataataaac gccaactcct ccacctaggt caatttctgt tagttgtatg ttgaattttt
     6001 cttttatttc ttttaccaag ttcatcatta tatccactgt atctatgtat ggttctacat
     6061 caaatatttg tgaacctata tgagcgtgaa gacccacaag tttaatattt ttatattcac
     6121 ttaatttttc tattgctcta aataaatctc catttactaa agcaaatcca aatttagaat
     6181 ctatctgtcc agtttttata taatcatgtg tatgagcttc tataccagga gttattctaa
     6241 agtatatctc ttgagtttta cctttatctt cacataatgc ttcaagcaaa tctaattcat
     6301 aaaaattatc caccacaaat ttacctacac ctaaatctaa tcccatgttt atttcttctt
     6361 tagtcttatt gtttccatga aagaaaactt tttccatagg aaaatttgat ttataagctg
     6421 tatataactc gcctcctgaa actacatcta aacacatttg ttcttcattt ataagattac
     6481 acatgtaaag aggtaaaaaa gctttccctg cataagcaac cttatttttt ccctctctag
     6541 ccttaaaata ttctacatat tctctacaat tttgtctaac taaagcttca tcaaatacat
     6601 aaagtggagt ttgatatttt ttactaagtt ctaaacaact cactcctcca atatataatt
     6661 catcattatt tacagtcata gttccatgaa gtttcataat agcctcccca aattttatat
     6721 attaaatact tctgctattt tttctatagc tacttgctta tcatcagaat ttatagcaca
     6781 agttatacga atctctgatg tagttataag ttttatcatt ataccatttt cattgaatat
     6841 cttaaatact ttagcagcaa ctccagaagt atttttcata ccaagaccta ctaaagaaaa
     6901 tttagtgata ttattatcaa tcactacatg ttcttcatct gtatatttag atactatctt
     6961 tttacattct cccaactctt cttttggaac tgtaaatgat acacttatct tatctaaaat
     7021 aggtgcagtt tggcttatca tatctacact tatacctata gttgctatat cttcaaataa
     7081 gctagatata ttttcagctt taaaatcttt tattgttata gaactgtcat catcactagt
     7141 agctaatcct gttattactt tatcctctaa tttcatgtct tttccccctc ttatatatgt
     7201 tcctttttct gtaccacatg tacgtccgac atagatttca acaccatatt tttgtgcaag
     7261 ctctatactt cttgaatgca ttacttgtgc tcctaaactc gctaactcaa gcatttcttc
     7321 atattcaatc tcatcaagtt tactagcctt tgaatatttt cttgggtctg taaaataaat
     7381 tccatcaaca tctgtatata tctcacattt tccatttaat ttaaccgcaa gagctacagc
     7441 agatgtatct gaaccacctc ttccaagagt ggttacatca ccatcttcgt tgattccctg
     7501 aaatccagtt actatcacga catttccttc atctaaacta tttttaattc tgtttacgtt
     7561 tatatcatca atttgagact ttccatgaag accactcgtt tttatattta actggtaagc
     7621 attataactt atagctttac atccaagtgc atttaatgct attgataata aagatgctga
     7681 aatcatttca ccagtagaca ttaaagcatc taattccctc ttactaggtt cattactcaa
     7741 ttcctttgct aaagttatat attcatcagt ggattttccc atggcagaca caactattac
     7801 catttgtgga ttttcttttc ttcgttctat tatattttct gctattgatt ttattttttc
     7861 agtatctgct actgaacttc caccatattt ttgaacaatt atactcatgc tttctccccc
     7921 tcaagctaaa ttttgataaa taaaaacgcc caaaggtata ctttggacgt gtaaatttca
     7981 tagaccaagt aaccttgtag ctcaccactt taaaagtgac agccttatgc atattctgca
     8041 taagtccaga aaatttgtcc gtcaacaaaa tttcttcggc tatataccct ttcatcaatt
     8101 atcaacgctt accagctcct attgaatact attgaataca gctacctcta ccctaggctc
     8161 attattttta attaatttat taatatagtt ttatcatatt ctatataata ttgcaacaat
     8221 tattttacaa aatgtggcaa atcgatagtt ttcttttcta aagttagctt atatacaatt
     8281 aaatagttta tttaatccta aatctataaa atttatgcta tactcattat catatctctc
     8341 taaatcattt aattcggata gattatctgg tgtaactacc aaaacgtttg gtactttaaa
     8401 aaatggaatt gtagatttat ctattttttt agaaagattt tcgtatttag aaatgtctat
     8461 ttcattattt aagtcaacat caactaaaac ttgctttata ttaccaaatt ggtctgtata
     8521 ttcaataaat aaatcgtatt tcacatcatc tacactaaca tttcggtaaa atctttttac
     8581 atcacaacct gcagtattga ttctaacaac taattctgat cctactagag cctttattaa
     8641 atcatctccc ttaaaaagtt tactaccgtt taaatagtat acataagaga ggtctttata
     8701 attataataa tccacatcac aaggatattt ttttagtgta tattcactac acatttttct
     8761 caaagttttt ttaaaatttt ttttattgta tcttttttgg tctccataaa tttttctaaa
     8821 ttgagactct gtaacacatc taaccctgct aattaaaagt aatatctctt tttccatatt
     8881 cgtcatagta cattctcctt gaagtattat ttgcaaagtt gtactaatat tatattaatt
     8941 ttatgacatt aaatttacaa agaattaaaa taaaatagct aatttttata gaattaaatt
     9001 ctataaaaat tagctatcac tatgttaaat actattatca atctttttat ttaaattata
     9061 cattaccttg attttcagaa tctttggaat ctgtattttc atcagttcct gttttttctt
     9121 ttgctttttt atcttcaaag tttgcaatat ttaggttatc aaattctgac atttctatta
     9181 caccagattc ttcttttgaa tacgatattt tgactttatc accaacctga gtcaatggca
     9241 attcgctaga tacttttgaa gtagccctaa atattatatc tttatttgaa tctaaagtta
     9301 cataataatt agtgttacca cctcgcacat ctgggcttat tcttgtcact gtgccttcta
     9361 atacctcatc ttttaaatca ttatcaagtt ttaaatcatt acccttagat tctaatgcat
     9421 ccttatagtt tcttaatgct tcattcttat cttcacctat tccaagtaca ttataatctt
     9481 caacagatac aaatgcaact ctcttaacaa gaccagcctt atcttttaat gatgatacat
     9541 atgttggctg acccaatata ttatacatta cagggaacgt cgcttcataa tttttttctt
     9601 gaacattacc ttcagctgat ttcattgcag ccgtttcagt agctcctggt tgtttatata
     9661 atctagcttc ttttgttcta gaatcaacta acataaatcc aattgtagat tcatctccac
     9721 ctgaagatgt tatacctgta taccaataag acctgttatc attgccataa actagtgatg
     9781 taccttctgt tggtactaaa actccctttt ctgatataac agagtttaaa aatccattaa
     9841 cataaacacc ccagtcttta atttggtctg ttacaaagct ttgtggttgt attctatcca
     9901 cccatttagg cgtgttttta acatcataaa catttatttt tccagtttct gcatcaacag
     9961 tggctattcc tgttgcattt gctcctccat agccaatttt atgttcatat aaacttacaa
    10021 cccaataagg tcttccttca tcatttattt caagagtgaa atctgtcata ccaacattta
    10081 caataccatg tatgtataaa tgtctttgta aatcctgatg taagtaggct tctggttggt
    10141 aaactatctt tattggcttt ccatctattt cttgaactaa ttggacgtct tgaggattac
    10201 tagctgatac ttttacataa ccacttgtac cacttagaga tgttatccat ttaattatgt
    10261 ctctgtgaac aagaggcgct acccagtaca actctccatc tacattttgt atatgaaatt
    10321 ttcctaattt ggatacactc cctattgcag gaacttctcc aagctttttg tcacctaatt
    10381 tcattgccat atcttcatct acaagacgaa tgtcatttac actgacaggg ctaatgtcat
    10441 cagtaaattt actttcagtt acttttccca atagttctct atatgatttt gcatgaagta
    10501 caggtgtaga agttataaag ggaactacta caatatacac aagcaaagct attgctattg
    10561 aaaaattata tttagccatt ttagatgctc tttcatttct atctaacatc atatctagta
    10621 ttcctgctac aacaaagaaa attattccta ctgaaaataa agatgtaaaa tctaatctta
    10681 gtacaggtaa tttaataaat gcataaatta ttacaattat taatgcaact ccatatgttt
    10741 taagatatcg tttcatttaa tactcctctc taaaaaatgt tattattact attatatcca
    10801 tatatttaca aaaaataaat atttatcata tttattatat attaagatat ctttatatat
    10861 ttatagttct gcttattcaa ctatatttaa cattatacgt gtatgtataa atacttttta
    10921 tacactgttt gtactatcca tcccgcacct aaaggagtgg gatttttgca ctattctgta
    10981 ttatatatat ccaaaaatat tataaaaata caaatattag cagaaattta aaaactgaag
    11041 aaagtattct aactaagatt tacaaattct taatcctatc gaagttaaac tactatcttc
    11101 agcctaatta tctagcaata tttttttata tgaaaaactc taaatcaagt ttttaaatgt
    11161 ttgcgatttt tgatacataa gaatgttgtc tagaattata ttctgataat aaaccttcat
    11221 actctaaggt taagccagat aaattataaa aatcatttgg cgttacttca aatgcttgtt
    11281 tatttaaaat gtctatctca cttttttcta acatgtcagc aacaaaattt gaacatacat
    11341 atttatattc agattgtctc tgaatattca ttagtaaata tattaatgcc attgtatcgt
    11401 aatagtaatc ttctctataa tcactaatta attttatatt tttatataga ttttcatatt
    11461 gtaaattatc tacttctaac gaatataccc tacacacagt gttttttctt atagcatata
    11521 atccttgatt tatattttct tcaacaaatc ctccaataaa tggattcctt ggatttagcc
    11581 ttccaaaaga atacattggt tttagatttt catttaatga tattgacaca tgtgtataca
    11641 gctttttact tatattcctt attaagtaag ataatatagt tcctgtatat gttgttacaa
    11701 tatagacttt attcatcatt tccccccaat ctagtaacta aataatatta tacacttaca
    11761 atttaatatc ataagatatt ctaacataat aaatgtggtt ttacaaattt tgattttaag
    11821 gtactttaat attatataat ataataaaaa tataaatata agttttctat atttttaacc
    11881 aacagatgtt ttcttcaaat taatcagatg atttagtata tcttgaacct ttccagagtc
    11941 ctttaaatat cctaatgccc catttatttg tgattttaaa tctatttcta cttccatatc
    12001 caaatcaaca tttccttttt ttatagatat atttttaagt gttattggat aaagataact
    12061 tttttccaaa gtaatcttat ttccattaac ctcaaatgga acttttttat tgtagttact
    12121 taatattttt tctagcattt tatcacttag tttaaatttt ccaattttca cattctcaag
    12181 acttacaact aagtttccat cctttaaagt aggtctcaat tcaagttcat attgactatt
    12241 taccaaacca aataccttat atggtcctgc tacctttatt ttaccatttt tcatttcaac
    12301 aaaattattt tcaagttcat taattccatg cttctgcatc aatgtatata ttaaattttt
    12361 aaactcttcc tctgaaacag atatttttcc aaccattcta agtggatttt ttactacctc
    12421 catagaattt atatatgagc cttttgataa atattcttca tctatgattt tattattttg
    12481 tgaactaaca tcatatcttt cttttggtgt caagatatat acaacaattc ctacaagtac
    12541 taaaacaata acaattaaac ttaacaaaat ctttgcaacc tttcccataa tcgtctcctt
    12601 tacaaatctg tcatcagatt taaaataaat ttagataact aacttcacat aatattctta
    12661 acaatataca tactataata cagtctttta aaaattaatt caaccaatct aatgttttgt
    12721 aaataaactg taaaaacatg tttttagtat aaaagttaat attttgcata atactcttaa
    12781 ttacaccttt atttttttct aatcttggat taaaattaat attatgcaat acagtgtagt
    12841 gttctgtatt ataatcaaat taaataggag gtatagaata tgtcaaatga aacgaactca
    12901 tctaacttta taaagaatat tattataaac gacttagaaa caggaaaaca tgacagtatc
    12961 ataactcgtt ttccacctga gccaaacgga tatttacata ttggtcatgc aaaaagtata
    13021 tgtcttaatt ttggattagc taaggagttt aatggaaaag ctaatttaag atttgatgat
    13081 acaaacccat taaaagagga tgttgaatat gtagagtcca taaaagaaga tgtaaagtgg
    13141 ttaggatttg attggaacga gttaaatttt gcatctaact actttgatga aatgtataag
    13201 agagctttaa tactaataaa aaagggtaaa gcttatgtat gtgatttgac acaagaggaa
    13261 atgagagaat atcgtggtac tctaactgaa ccaggaaaag aaagtcctca tagaaacaga
    13321 actattgaag aaaaccttga tttatttgaa agaatgaaaa atggtgaatt taaagatggt
    13381 gaaaaaacat taagagccaa aatagatatg tcttctccaa atataaacct tagagaccca
    13441 attatatata gaatatctca ttcaacacac cataatacag gagataaatg gtgcatatat
    13501 cctatgtatg cttttgctca tccaattgaa gatgcaattg aaggaataac tcactctata
    13561 tgtactttag agtttgaaga ccaaagacct ctttatgatt ggtttgttaa agaatgtgag
    13621 atggaaaata tacctagaca aatagaattt gctagactta atataaataa tactgtcatg
    13681 agtaaaagga aattaaaaca acttgtagat gagggtattg ttgatggttg ggatgaccct
    13741 cgtgttccta caatatccgg aatcagacgt aagggatata ctgcagaagc attgcgcaat
    13801 ttctgtagtg aaataggggt atcaaaagtt aactctacgg tagatagtca aatgcttgat
    13861 tatttcctaa gagaaaactt acaaccaaag gctcctctta ctatgggagt tttaagacct
    13921 ttaaaactta ttataactaa ttacccagaa gataagattg agatgcttga aatagagaat
    13981 aatgctaaag atgaatctca aggaaagaga ttagttcctt tctctagaga attgtatata
    14041 gaacaagatg attttatgga agaacctgtt aagaaatatt ttagattttt cccaggaaat
    14101 gaagtccgtt taaaaggtgc ttattttgta aaatgtactg atgtaattaa ggatgaaaat
    14161 ggaaatgtag ttgaaataca tggtacttat gaccctgaaa ctaagagtgg ctctggcttt
    14221 acaggacgta aggtaaaatc tacaatacat tgggttgatg ctaaatcagc tatcccatgt
    14281 gaatttagat tatttgaacc attaattctt gatgatatac ctgaaaatga aggtaaacat
    14341 ttcttagaac aaataaatcc taattcattg gaaatattac aaggttttgt tgaacctaca
    14401 cagataaaag atgctaaacc ttttgataaa ttccaatttg ttagaaatgg attctttagt
    14461 atagataata aatatacaac tgatgaaaaa tttgtattta atagaatagt tcctctaaaa
    14521 agttctttta aaccaggtaa ataatcttac aatcaaaaaa tgaagactta aaatataaat
    14581 tacttctact ataaataaac ttagttagaa gtaatttttt atttgagtct tcatcattta
    14641 ctttaaatga ttaacttttt tcactacaga ttcccatgac ttctattcca tcttttatgc
    14701 attctatgtt aagaggaaaa tctggtcctt tttctccgtc aatatctgtt ataagtgaat
    14761 cttcacattc tatatgcacc tttttagttt taaagtatag tatttcattt ccattatatt
    14821 gatctaaata atcacctcta agcacactta tcaaaactgg tattgatttt ggtattggca
    14881 ttcctttaaa aataattaca tccaaatatc catcatctat ttcagcctta tatgctagat
    14941 ttatatttcc tgctgttttg ccattaaaaa tcaacataag atacatatct ccatcataat
    15001 acatttcctc agaagatact tttatcttaa atttcctcat atacaatgct tcttctattc
    15061 cctttatata ataagaaatt cttccaaatg aattttttaa gtctgtgttt atcctttgtg
    15121 atacatccgt aaacatacca gcacttgcaa catttataaa gtacttatta ttgactttcc
    15181 ctatgtctat tttctttggt tttgaattta tgatttcatt tatagcttct tttatatcaa
    15241 atgaaatttg aagagcattt gaaaaatcat ttgcagttcc tgtaggcaaa attccaattg
    15301 gaatttttat gtctaattct ttcattgcat ttactactaa atctacagta ccatcaccac
    15361 cagctatcaa tatgtgttca taagaactat caacttcctt aaatgcattc tttacaggtt
    15421 ctttaatagt taatctatag ggtatcaata aataattttt ttcttgatat aattctatga
    15481 tagtgtctaa atttgataat atcttttttt cacctgaatt aggattgtat ataagtttta
    15541 cttttttcat tatttctcct tactcatttt attcttttag tatccaaaat cttcatttaa
    15601 aaaaatcaca tgtattcttt ctggtgttaa ttgtcttttt ataagtgtat aactacagca
    15661 tattcttcct ggacttgaac agtctataca tataccagta gtcttacatc cagtatttgt
    15721 acttaatctt ttacaattgg ctggagcagc tattgttttt gttcttttta tagcttcatc
    15781 tacatcttta actattttat ttactcctgc tataactatt actttatcag gtccatatat
    15841 catagcagca actctattcc cattcccatc taaattgtaa agttctccat cctctgttat
    15901 cgcattagta cttgtaaaat aagcatctgc agaaaatgac tttctatata tttctttcat
    15961 ttcttctggt ttgatatctt ttgcatatct atcaagaaaa ttatattttt ctcttataaa
    16021 atcaatcact cctgtttcaa ataaggtcat agaacctcca catcctacta gagaacctgc
    16081 tttaactatt tcttcaattt ttttaagaag ctcttctttg ttacttacta aatacccttt
    16141 catattattg ttttccaaag attttattgt tttttctatt cttttttcat taagccaatt
    16201 taaattttga tccattttaa cttccccctt atttttaata tgtacttaat tatttataaa
    16261 ctttattttc tttataagtt tattttagta catctaaaaa aaaatacaat ataaaactta
    16321 aatagtttta cataattttt tccaaaataa cttactcaat caaaaaagga aagtagatgt
    16381 actattctac tttccctata ttgtatgtag tatttattgc ctaaaatcta tatattaatt
    16441 atatgtttca tattatataa tatcacagtt aattaaaatg taatactatc ttctttttaa
    16501 acatataaat tgtattatta aatttaatat atccaacttc aataaatctt attaatttga
    16561 tgaagaagat gctatagctg cacttgttgc tgccattaca catgcaattt gaatagcaac
    16621 aacaatattt aaaaatatat tattagttat agagcctata ttattctcat ttcgtatcaa
    16681 atctgcataa attgaagcta caatagcaga actaatcatt actctattac tttttcctaa
    16741 agaccaattt ccaaagcctt tttcttcttt aagtttattt gaaacatttt ttatctcttc
    16801 tattatttca tcttctctat aatctaataa tgaaattgct cctattattg gatatccata
    16861 ataattcatt ttacaatcat tttctttaaa tgctttttta agttcaatag tctttttaca
    16921 tttaagcata gttctatcat cactaaataa aagaatttgg gataatgctt gtaaatcatt
    16981 tcctttataa aaaccatttt catttagaaa ttcataacat ttttctatgt attctaaatc
    17041 ttcatctaaa ttttttgaat gaattgcaat aagtgctata ttacaatagt catcactaga
    17101 agttagaaat ggatgttttt tcctcatgta atcatatatt attttcattt ttgatataca
    17161 tgtaagataa tccattttct ctctattttc ataaactatt gatgctgtaa gtggtaaata
    17221 tgtatcgccc caaaactttt cacttttaag ttctttgtat atatctaaaa tcatcttaaa
    17281 actactttct ggatttgatt caaacgaaag tagtgttgcc atataaaaca tattatatcc
    17341 tctaaaatta gagaataatc cagtattttt tttaataagc tctattcgtt cttccactaa
    17401 tctaggactt attttcttgt tcttaagggt aaatgcaagt gcacaactat gttgtatcaa
    17461 tcccatttgc caagaacctt taacttcatt taatgctttg taattttcta ttaataagtt
    17521 tacttttcca tttataaacg attgttccat attgccctcc tagtaatata tctcattgta
    17581 ctaatagttt tatatttatt atatatatat taaatactac aatcaataca tattacttca
    17641 aagaacatca ttcttcaaca ataatgtagc cttttttgta atgtcttccc atattattga
    17701 ctctatcata gtactctgat tcactttcat tactccattt gggcacaaat acatctattg
    17761 cattagaatt actaaaatac ttactagacc ccctatccat aacagttttt aattttccat
    17821 ctacaataat cttagttcca aaacttaagt gattgtttgc tacaaaacca tcttctaaat
    17881 catctcctgt agcagttatc gctccatatc cattttcttg attaagactt gtgtaataac
    17941 taacttcaaa agttataggt actaacttct ttattttaat acctaactga ttttgtagtt
    18001 tctccttttg tactttcaac ttatactcat cactattttt ataatcttcc ataccttgat
    18061 tatacttgga attaaagctt ttacctgact ttactatagt atctatattt actatagatt
    18121 ctttacaatg atctgcatct atttttgttt ctccatttac caataatgga gttaaacata
    18181 cactacatac aacacatgta atcaatgctt ctttaagctt cataaattcc ccccttatta
    18241 ttttgatata ttagcatatt taatattata tgtctacatt tagatttaaa taccacaccc
    18301 atttgcttta agaagttgtc ttatatttaa ttcaccttaa acacttataa atcctctatc
    18361 ttagaatcat atagaataaa gcttttatca ttaaatattt tttattaatc ttttaaaatc
    18421 taaaactact ttatctaatt ttctcttttt tagaatttaa gaattaaaat tctataattt
    18481 taaaacatat tgaatttatt tttttgagat gatataattt tcttaagagg tggttgatat
    18541 gataaaaaat acaaaacaaa ttacagtaga agttaatgaa attttattac aagaaatgtc
    18601 taagataact aattacgaaa ataatatttt gacagatttg ataaatgaat caattgtaaa
    18661 ttatattctt gaaaacaaaa aacataatat tgaaaataaa gatttagaag aagtgattaa
    18721 attttataaa aaagaaaata ctgaaaaacc taaaagtgca gcaagagcta tagctgaagc
    18781 aaaaactcat actctgtatt aatcaaataa aaaagttcct aaaaactagg aactttttta
    18841 tattaataat tattaatata tctcaatatt tatctcaaat ctatcaatat aagcatgttt
    18901 aatacaatct attgtatact tatcttaccc tagaaataat caaaacaaaa ataaaattat
    18961 gccctttata tctaaaacaa ttaatttaca tgattaatat acaaaaattc tgacttttaa
    19021 attcgtatac aatatcaaac taaaataata ttaatgacaa acccaatata aattaaattc
    19081 aaacaggttt gattttacat caaacttatt gtattaatat taaataacaa gacaaaaata
    19141 tttataaaaa tcacaaattt tacataaaac tttatatttg attcatttaa ctaattattg
    19201 taaaaactat ttattttatg ataattaact acaccaaatt attcatcttt tttaatatct
    19261 ttaacccatt tttcaacaga gttcaattct tcttcattta cccccttttt gaacaaggat
    19321 ttcataaaac tctcaataga acttccatgc atattatcta aaaaagtttt tgtttcaaaa
    19381 tgtaaatact cttcttctcc aataagaact gtataatgtg tatgtctatc aatttttctt
    19441 gcacttaaga attgcttatt tactaatctt gataaaagtg ttagtgttgt agtttgcttc
    19501 caattatata gtttttccat agcttcaatg acatcttttg atgctactgt aaaatctgaa
    19561 ctccaaataa atttcatgac ttttaattct gctggtggta tcttagtaat agtcatatga
    19621 ttttacactc ctctcaaact tctacataat taaatactat attaatagac ttttcgagtc
    19681 aaaggtttta tttaaaatat ctcatccaaa tttattaata caaaaaattt atatttttat
    19741 tcaaaattaa
//
LOCUS       DAMJVG010000074        19723 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.074, whole genome shotgun sequence.
ACCESSION   DAMJVG010000074 DAMJVG010000000
VERSION     DAMJVG010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19723)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19723)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19723
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.074"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            119..1483
                     /locus_tag="PC512_002851"
     CDS             119..1483
                     /locus_tag="PC512_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase"
                     /protein_id="HDF2442584.1"
                     /translation="MDIKELVKMQRKYYNTGKTRDISFRIEQLKKLKLVVSQNEEKIL
                     LALKKDLNKSDFEGFMTEVGMFYSELNFAIKNIRKWSKIKRVKSSMVNFPSISKVVPQ
                     PYGVTLIMSPWNYPFQLALIPLVWSLVAGNCVILKPSEYSVSTSSVVKDIVEDTFSKE
                     YVAVVQGSQEESEKLLLERFDYIFFTGSTNVGKIIMKSASEHLTPITLELGGKSPCII
                     LKDANIDLTAKRLTWGKLINAGQTCVAPDYVLVHEDRKNELIEKIKYYTNKYFGDNPC
                     NNEQFPKIINQRHFNRILSLIDKDKIVYGGNYNKETLKIEPTIVDNVNWDDNIMKEEI
                     FGPIFPILTYKDLDEVIQKIIQMPNPLALYIFTKNKYLENKLLEMIPAGGCCINDTVT
                     HIATNYLPFGGIGESGMGSYHGKAGFDTFTHYKSVLKKLNLDVPIRYAPYDNKLIKVL
                     KKIM"
     gene            1622..2788
                     /locus_tag="PC512_002852"
     CDS             1622..2788
                     /locus_tag="PC512_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDF2442585.1"
                     /translation="MKINWNTKYTTIAIYTFIIAASSIIFYLVSSQIDVFSNNLDAIF
                     TTLQPFIIGFAIAYLLNFILKFYEDRIFIKSEKLKKLKQSSKRGLGLLLTYATATLIL
                     YLFMHFVLPQVIESIVGLANDIPMYVNNATKLIDKLMTDLNLDEQYFNLAVDKWNEFV
                     TYIIKFVTDLIPILGSMLKNVASSIWNIVLGLIVSVYLLIDKEKFYGLSKKITYAVFT
                     EKQAARILELTHRSNYTFGRFLGGKILDSFIIGILTFVILTLVKMPYTLLISVIIGIT
                     NIIPFFGPLFGAIPSTLIVMFVSPIKAFWLLLIILIIQQIDGNIIGPKILGDSIGISA
                     FWILFSLLVAGKLLGFIGMVIGVPMFAVIYSIIKDIVESKLDKKGLPTDTSDYM"
     gene            2905..3687
                     /locus_tag="PC512_002853"
     CDS             2905..3687
                     /locus_tag="PC512_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HDF2442586.1"
                     /translation="MAFIECKFKSKYTGGETDIIVILPVANGKELFSGKEIYDFEGKF
                     KTLYLFHGLEDDQSSWIRYTNVEHYAKNKNIALVIPRVETSFYTDMAYGHQYFTFVSE
                     ELPKFVRAIFPLSDKREDNFVAGMSMGGYGALKLALSKPKEFSAVASFSGSPDMIHEL
                     ENQQIETNADILFHDFGRPEDARNSENDLLYILKNLKERNEDIPKIYQFCGDRDFLYK
                     NNQMFKKYADSLGVDVEYEECVGGHEWRLWNLWIKKFIDIIG"
     gene            complement(3806..4459)
                     /locus_tag="PC512_002854"
     CDS             complement(3806..4459)
                     /locus_tag="PC512_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2442587.1"
                     /translation="MSKSEKGKETKASIISAARELFFEQGYHKTTTRQIAERANINLG
                     LISYYFSSKSEIGAIIYEDIRNEMQSLIYNYHEEGTMMMFFLAMNADLCFLLKNEAYR
                     NFYLDIAYEEAILSYQRSVTEMVMKRYVNDKESIEHDELILSCIGILAMKPEIIRVYT
                     SHKYDISSQAVIKHFTKQFLINLGHSTDLCEEILEELSKYYIDIVDNFTPIITRVRT"
     gene            complement(4483..5847)
                     /locus_tag="PC512_002855"
     CDS             complement(4483..5847)
                     /locus_tag="PC512_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HDF2442588.1"
                     /translation="MLLLIVTCAIYIWIGFYFSKKVKTASDFLIAGRNLPLPILAATI
                     AATSFGGGCLVGGVQWGAERGLWVGMYSTIGAALACFINAFFAGKLRSLSCDITPADY
                     IETRYGHSVFLRAYQSLVTPISILAIMGSQLISFGSVSTAFGIPYDIAVIIGVIVIII
                     YTYTSGMWGVAVSAFIQLAICIVFLPIVAYISLKLVGDNPLLMLQSMVKEPFFPGNKS
                     ISDFMYTVLPLVLGSIFSYESFLRYQCADNAKNAVKSSVIAGFILLFLAFPIGIIGAI
                     GGSLFPNISSVQVLPQMISTTLPPLISVLFLAAILAAIMSTADSLMTSMSAIISRDIY
                     NKLLHPNIEFNDLKNTLKYSQIASALTAIIGAIIALKFDSLLELLFWPAPLCTGVIFA
                     PFVIGLCWKGATKKGAIYAVIVSVILALLNMIGILTVFDRILVPIIGGSITIFIVSKF
                     SKKD"
     gene            6506..7936
                     /locus_tag="PC512_002856"
     CDS             6506..7936
                     /locus_tag="PC512_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2442589.1"
                     /translation="MSSQESKPKGNLISNFRDDMRDPKKRAIYTYSSSINLAYNFIGY
                     FVSTVTNIFLTDVAKLGVIMAGGMQIIQSFIKIAVAPITGTVFDKQPFKKGKYYPWLR
                     YAPAALALTYGIFFIVPLMKISPALLLPLMTALLLIASCAQQVVFTIIYAIYPVVAKT
                     PRDRVIGSTTTNIFKEVGKFLVGFSYPLLLVLFADVLGGEGMGYLGTYLFFAAGCLLV
                     FWFSSTEIIKSGAEEEVLQKEEKPKIKASEMAKALFTNVPLMMAFCLEFLICIRSIGL
                     GPLAPYYFKYVIEDERGLAVFLSIMPLVSVAFMFFAPVFIKICREQKLASIISFSICA
                     LCHLLVAWTPWGKTTLGVTMLLAIGGGFSNVVSIINLNFFAGSCDYGHWKSGKDLPGL
                     SMSLYPVAIQVGVLLATTIRTVLMNSMGYQADMVVTEAVKSGFINMISYSMAIPLIIA
                     VVIAILYPVSDKKLNQIREELNQRNA"
     gene            8039..9142
                     /locus_tag="PC512_002857"
     CDS             8039..9142
                     /locus_tag="PC512_002857"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HDF2442590.1"
                     /translation="MIEKLLRNTVKELHQYVPGEPIEKVKEKYGVKEIIKLASNENPL
                     GPSPKAIEAMIEMLKQGQLYPEPEANELRRKLAEKLDLKPENFIVANGADNVITLIGE
                     AFINRGDEVIYCNPTFPSYRTATIKNEGIPVEVPLTEDYKYDLQGILDKITDKTKLIC
                     VCNPNNPTGTIVDDKELEEFLKKVPENIITILDEAYIEFLTVPNYVDGLKYVRENYNV
                     IVTRTFSKIYGLAGLRVGYGIAKDEIIRTLFTVKEPFSANRVAISGATAALDDEEFIK
                     ETYELNRVGMAYFKEEFTKMGFDVVDSQSNFLYVDMKTDIPKLFEDLKKRGFVIRPSA
                     THARVSIGTMEENKKFVAVLKEILNIKGEPSIG"
     gene            9157..9393
                     /locus_tag="PC512_002858"
     CDS             9157..9393
                     /locus_tag="PC512_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF2442591.1"
                     /translation="MKRGVDMNLKINAERCKSCEYCVISCKKGALKISSKINKEGYAH
                     VEVDESKCILCGICYQVCPDNVFEIIKEEACQEA"
     gene            9410..10459
                     /gene="vorB"
                     /locus_tag="PC512_002859"
     CDS             9410..10459
                     /gene="vorB"
                     /locus_tag="PC512_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HDF2442592.1"
                     /translation="MKKMWKGNHAIAEAALRGGCEFYAGYPITPQTEVIEFLSHRMSE
                     LGRTFIQSENEMAAIYMVYGAYASGMRSMTSSSGPGISLKQEGISYLCANHYPCVIVN
                     VQRWGPGLGSLDSAQTDYLRDTRGGGNGDYHLIVYAPNSIQETVDLMYNSFDVAEKYR
                     VPVEILTEAALGQMMEPVEFPEFKKREGDLGWTYDGSNRDHAKVADNQKPTFCMEKRM
                     RITENEQQWEDYQVEDAEYVFVAFGIPSRTTMNAVRRLREQGEKVGIIRPITVWPFPY
                     KAFEKVSKDVKGFISVESTDTGQLVEDVALTSKKVCKENVPVYGLFSGNHIPKTLQVM
                     DTYSKIKSGEIKEVF"
     gene            10461..11201
                     /locus_tag="PC512_002860"
     CDS             10461..11201
                     /locus_tag="PC512_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HDF2442593.1"
                     /translation="MATEKLTPSVVSIPNKFCPGCGHGIVNRIIAEVIEEHGYEKNHV
                     LTLGVGCVCNMNFSWNGDKMQTAHGRASSTAIGVKVALPDTLVMTYQGDGDAYVIGLS
                     ETLNTAYRNHNVTVFVINNNNFAMTGGQMSWTTMPGQVTTTSVNGRDIKTTGSPLKVP
                     EMVANFFDVAYVARGSVHSPKEIINLKKYIKNAIEAQLNGEGYSLVEILAPCPTNWGV
                     SLEKSIKWMEEEIVPYYALGEFKQRDGE"
     gene            11204..11743
                     /locus_tag="PC512_002861"
     CDS             11204..11743
                     /locus_tag="PC512_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HDF2442594.1"
                     /translation="MEKELVFAGFGGQGVLTLGLIVAESALELGKQVTWMPAYGPTMR
                     GGKAYSVVKFSDESIGGPDMEEIDVLVAMNKPSLDYINLVKEGGTVVINTSAIDENVT
                     LREDISVVKINCQELAQKVNNPKAANIVVLGALIAKTGLFEKELALKTMCDFFEEKGK
                     GKFNVQNEAAFMEGYNNAI"
     gene            11867..13966
                     /locus_tag="PC512_002862"
     CDS             11867..13966
                     /locus_tag="PC512_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate--CoA ligase family protein"
                     /protein_id="HDF2442595.1"
                     /translation="MSLEKLIRPKSIAIVGVTDKLGFGRSAALSIVKSKETDRVYYVN
                     PKREELFGRKCYKTIQEVPEVVDCVVVCTPRNVVPSVLKDSGELGTKAAVVYASGFAE
                     EGTEEGTDLENQLIEISNTYDMKILGPNCMGLLNCIDKVNLWAGGSKWDLDTKKPGIG
                     IVGQSGFITAEIVSSDYFNISYGFSTGNGNIVTLEDAVDFLVDDDYASVIAIYLEGLK
                     NPQKFIDALKRAAQKRKPVIILKSGRSEKGAISAASHTGNLAGSSKAFESIFEKYGVI
                     SVENLEQFMCLAQAFSVLDGNLPANSNFAAINFSGGENTICADLAEENGVELAEISSE
                     TKEEMKKYLPGFATPKNPLDATTALFHEKDMIVGLLHTFEKDDSVGFTMVGANIRDEE
                     NEMHETLCKAVSEAREQGLKKPVFAVPTLEGNRYLDYRTRLEDNQVPIMSSVGTTFTC
                     FNKMAKFIDYDYSKRTLEFKAVKKRESNNVVALSELDSKIEMKKYGVPVPGQGNAKSI
                     DELDEILKYIKYPVVLKINSSEILHKSDVGGVKIGIENRDEAVDAYNEILTNVKKAKP
                     DANIDGILVQEMVESGIEIIIGITNDDQFGPMLLVGLGGVFVEVFKDTTLYPLPINHD
                     EAIMMLKKLKSFKLLNGYRGSEPCDIDALADMMVKLGKYAYENKDEVKEIDLNPVFVY
                     PKGKGVCAVDALIVKYK"
     gene            complement(14233..14748)
                     /locus_tag="PC512_002863"
     CDS             complement(14233..14748)
                     /locus_tag="PC512_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin"
                     /protein_id="HDF2442596.1"
                     /translation="MISAKMEKLLNEQINHELYSAYLYLSMSSYLEAEGLKGFSNWFY
                     VQYKEETDHAMFFYKYLHNVGGKVQLDAIPMPDSDFTSAMDILERTLAHEKKVTALIN
                     NLAAVANSESDFRTSQFLLWFISEQAEEETNCEDNIKRVKLAGEGGLFFVDQEFANRT
                     YAAPTNPPVTI"
     gene            complement(14840..16051)
                     /locus_tag="PC512_002864"
     CDS             complement(14840..16051)
                     /locus_tag="PC512_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HDF2442597.1"
                     /translation="MSNKQGSNIKDVKIKNKLIILKLLSTNTPMSRVDLAKSTGLTKM
                     TLSNLVTELINENMIREIESSTLNAHSSGRKPILLDISNISPCICGILIRRNICKVII
                     SDLKGNIVKQLSETYPKCLSNDVLKDIIKRMFTKIMKINKRDIIGIGISSIGPVDDIN
                     GTILNPPDFGNVSNLNIVDFIKEMSDLPIFLINDANSGALAEKMYGLGKNISNYIYLH
                     IMNGIGAGLVLENKLHTGNLGQSGEIGHTSINFSGPLCSCGNNGCLDYYTSVSNLIKR
                     IESLSHIYPNSPLINCKDFSLVKLIDEANNKDSLAMFLLDEFCTYVSYALVNTLTLID
                     CSSIIIGYDFNIPGTFIENTLLKKLTASASFSKYKKISVRHSNFGANAPLIGSIAIVS
                     YNFFNGSINFY"
     gene            16727..18169
                     /locus_tag="PC512_002865"
     CDS             16727..18169
                     /locus_tag="PC512_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HDF2442598.1"
                     /translation="MRTIRRVLALGLTLAIFLINVPNVDALTSDTIKGNNIYETAGLI
                     ADKKSYDTAIMVNMDNSIADGLSASGLAGAVDAPILLAQKNKIPNETKQRLKNVKKIY
                     IIGKELSISKSVETELKNTGAQVTRLGGDDRIKTSYSVAKEVNGIKKVDEVILTNAYK
                     GEADTISATPVSVRDIAPIVLTDGKSVPFSTSNVKTYAVGGSISMSTSLVNKTNAKRL
                     GGSDRYDTNKKVIKEFYPDASEFYLSDGYDLVNALTGSTIAKENPIVLVSESSDKSIL
                     AGADKITRLGSISDSVYNKCVSAAQNNGDSSTKGESPMKNETSILGQPTASLEACLKW
                     AKSKKANDLFIELIPILYDTAVQEGVNPVLAVAQSAKETGFCNFGGVLDASFKNPCGL
                     KTSVGGSDTDKNAHSRFDTWEEGILAQIQHLCLYAGQDGYPLSNPVDPRHEKSLFGKA
                     KTVESLSNNWAGGQYGQDLVRMMGEIEATK"
     gene            18211..18564
                     /locus_tag="PC512_002866"
     CDS             18211..18564
                     /locus_tag="PC512_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442599.1"
                     /translation="MKKSNIFSIIFPTVIMVLMFLTFATDIFNIPDIQSKSIFVVGMV
                     LIFPISFLIQGIICVLNKTNWILSLIVSLVTYIVLMYIFLNDSAYIYVLLYTAFYMIG
                     HITAKLYYKIKTFKN"
     gene            18755..19576
                     /locus_tag="PC512_002867"
     CDS             18755..19576
                     /locus_tag="PC512_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ family protein"
                     /protein_id="HDF2442600.1"
                     /translation="MNLIDNHIHTNFSSDGKDSMEDTIKKAISIGVRYLTFTDHLEHD
                     EDRGFCINYNDYVPVFNKFKEKYKKDIELLLGVEVGYRKHLKNEIEEIINSNPFDFVL
                     CSTHTIDNVPVPSKEYFKGLSKEDAYYKYFNSILETNREFGDYNIYGHLDYISRYGIY
                     SDNRVIYNDFKDVIDEVLKSIINNGSGIELNTSGYRYGLNAIHPNEDILKRYKELGGF
                     IVTVGSDSHRVEDICKDFDVAYDMLKYLDFKYVSLFKERETYFVNIEKVKSNNIA"
BASE COUNT         7507 a         2341 c         3365 g         6510 t
ORIGIN      
        1 ggaagattta tgttatattg agatgaattt attatgatat aaaaaataat gttaggataa
       61 atttaaatct ttttctaaaa atgtattaat ataattctta aagaaaggat ttttaataat
      121 ggatataaaa gagttagtta aaatgcaaag aaaatattat aatacaggta aaacaagaga
      181 tatatcgttt cgtatagaac agttgaagaa acttaagtta gttgtatcac aaaatgaaga
      241 aaaaatactt ttagcactaa agaaagattt aaataaatcg gattttgaag gttttatgac
      301 agaagtaggc atgttttata gtgaattaaa ctttgctata aagaatataa gaaaatggag
      361 caaaataaaa agagttaaat caagtatggt taattttcca tctatatcca aagttgttcc
      421 acaaccttat ggtgttactc tcataatgtc accttggaat tatccatttc aattagcact
      481 tataccatta gtttggtcat tagtagcagg gaattgtgtt atattaaaac cttctgaata
      541 ttctgtgtca acatctagtg tagttaaaga catagtggaa gatacttttt caaaagaata
      601 tgttgcagtt gttcaaggaa gtcaagaaga aagtgaaaag ttactattgg aaagatttga
      661 ttatatattt tttacaggaa gtactaatgt tggtaaaata atcatgaaat cagcatcaga
      721 gcatttaact cctattactt tagaacttgg aggaaaaagt ccttgtatca ttttaaaaga
      781 tgctaatata gaccttactg ccaaaagact tacttgggga aaactaataa atgcaggaca
      841 aacctgcgtg gctccagatt atgttttagt gcatgaagat agaaaaaatg agttaataga
      901 gaaaataaaa tattatacta ataagtattt tggagataat ccatgtaata atgagcaatt
      961 tcctaaaatc ataaatcaga gacattttaa tcggatatta tctcttattg ataaagataa
     1021 gatagtctat ggtggaaatt ataataagga gacattaaag atagagccaa ctatagtaga
     1081 caatgttaat tgggatgata atataatgaa ggaagaaata tttgggccta tatttcccat
     1141 tttaacatat aaagatttag atgaagtaat acaaaaaatt atacaaatgc caaatccatt
     1201 ggcactttat atttttacaa aaaataagta cctagaaaat aaacttttag aaatgattcc
     1261 agcaggcgga tgttgtatca atgatacagt tactcatata gctacgaatt acttaccttt
     1321 tggtggtatt ggtgaaagtg gtatgggctc atatcatgga aaagctggat tcgatacatt
     1381 tactcactat aagagtgtgt taaaaaaatt aaatttggat gtccctatta gatatgctcc
     1441 atacgataat aaattaatta aggttcttaa aaagataatg taggttatat tgtagaataa
     1501 taaatataaa taaaattgag tatttgtatt ctgaatatat tttattttta atttggtata
     1561 tttgttataa aagtggtgat tttgtgataa aatttaatta tatagaaata aggaggaaaa
     1621 aatgaaaatt aattggaata caaaatacac aacaatagca atttatacat ttataatagc
     1681 tgctagtagt attatatttt atctagtatc atcacaaatt gatgtatttt ctaataattt
     1741 agatgctata tttacaacat tacaaccttt tataatagga tttgctattg catatcttct
     1801 taattttatt ttaaagtttt atgaagacag aatttttata aaaagtgaga aattaaaaaa
     1861 actaaaacaa agttcaaaaa gaggcttggg tcttttatta acatatgcaa cagctacatt
     1921 gatactttac ttatttatgc atttcgtatt gccacaagta attgagagta ttgttggact
     1981 agcaaatgat atacctatgt atgtaaacaa tgcaactaag cttattgata aattaatgac
     2041 tgatttaaat cttgatgagc aatactttaa tttggcagtt gataagtgga atgagtttgt
     2101 tacatatatt ataaagtttg taacagattt aatcccaata ttaggaagta tgttaaagaa
     2161 tgtagcctct agtatatgga atattgtact aggattaatt gtttcagtat acttattaat
     2221 tgataaagaa aaattctatg gattaagcaa aaaaataact tatgcagtat ttacagaaaa
     2281 acaagctgcc agaattttag aattaactca tagaagtaac tatacatttg gaagattttt
     2341 aggtggcaaa atattagatt cattcattat aggtattcta acatttgtaa tacttacgtt
     2401 agttaaaatg ccatatacat tattaatatc agttataatt ggtattacaa atattatccc
     2461 tttctttgga cctttatttg gagctatacc atctacgcta atagtgatgt ttgtatctcc
     2521 tataaaagct ttctggttat tgttgattat attaataata caacagatag atggaaatat
     2581 tataggacct aaaatacttg gagattcaat tggtatatct gcattttgga ttttgttctc
     2641 cttattggtt gcaggaaaat tattaggttt tattggaatg gttataggag ttccaatgtt
     2701 tgcagtaatt tattctataa ttaaggatat tgttgaaagt aaattggata aaaagggatt
     2761 accgacagat acttccgatt atatgtagct aaaaaatatt atgtataatt aaaaatatat
     2821 aaattaagca atatttaaag cactgagaaa gttaaactct tggtgctttt tagatataaa
     2881 attattatag aagaggtgtt ttttgtggca tttatagaat gtaaatttaa atctaaatat
     2941 actggaggag aaactgatat aattgtaatt ttgcctgtag caaatggaaa agaacttttt
     3001 agtggtaaag agatatatga ttttgaaggt aaatttaaaa cattatactt atttcatggt
     3061 ttagaagatg accaaagctc atggattaga tatactaatg tagagcatta tgctaaaaat
     3121 aaaaatatag ccctagtaat accaagagta gaaactagtt tttataccga tatggcgtat
     3181 ggacaccaat attttacttt tgtaagcgag gaattaccta aatttgttag agctatattt
     3241 cctttatcag ataaaaggga agataacttt gtagctggta tgtctatggg gggatatgga
     3301 gctttaaaat tagcgctttc aaaaccaaaa gagttttcgg cagttgcaag tttttctggt
     3361 tcgcctgata tgattcatga gttagaaaat caacaaatag aaaccaatgc agacattcta
     3421 tttcacgatt ttggtagacc agaagacgct agaaatagtg agaatgattt actttacata
     3481 cttaagaacc ttaaagaaag aaatgaagat attcctaaaa tttatcaatt ttgtggtgat
     3541 agagattttt tatataaaaa taatcagatg tttaaaaaat atgcagattc tctgggtgta
     3601 gatgttgaat atgaagagtg tgtagggggg catgaatggc gtctttggaa tttatggata
     3661 aagaaattta tagatataat tggatagtac acttatggta ttaacaggta tactataaaa
     3721 tatctttaaa tatgataaag actgaaatcc taaaatcaaa ttatgatttt aaaatttcag
     3781 tctctaagaa tttaataaaa ttttattaag ttcttacacg agttattatt ggagtaaaat
     3841 tgtcaactat atctatatag tatttactca attcctctaa aatctcttcg cataaatccg
     3901 tactatgacc aagattaata agaaactgtt ttgtaaaatg ctttattaca gcttgagaag
     3961 atatatcgta cttgtgtgaa gtataaactc taattatttc aggtttcata gcaagtatac
     4021 caatacaaga aagtattaat tcatcatgtt ctatagattc tttatcatta acatatcttt
     4081 tcatgaccat ttcggttaca cttctttgat agcttaaaat agcttcttca taagctatat
     4141 ccaaataaaa atttctatat gcttcgtttt ttagaaggaa acaaaggtca gcattcatag
     4201 caagaaagaa catcatcata gtaccttctt catggtagtt atagattaaa gactgcattt
     4261 catttcttat atcttcatat attatagctc ctatttcgct tttacttgag aagtaatagc
     4321 ttattagacc taaatttata ttagctcttt ctgcaatttg cctagttgtt gtcttatgat
     4381 aaccttgctc aaaaaataat tctctagcag cacttataat actagctttt gtttctttgc
     4441 ccttttctga ttttgacata tttactgtgt atacctctct tttcaatctt tttttgaaaa
     4501 tttgctaact ataaatattg taatagaacc acctattata ggaaccaaaa ttctgtcaaa
     4561 tacagtaaga ataccaatca tatttaataa tgccaatata acacttacta taacagcata
     4621 gatagctcct ttttttgtag cacctttcca gcaaagacca attacaaatg gtgcaaatat
     4681 tacacctgta cataatggag ctggccaaaa caataattct aataaactat caaatttaag
     4741 tgctatgatt gcacctatta tagctgtcaa agctgatgca atttgagaat actttagagt
     4801 attttttaaa tcattaaatt ctatattagg atgtaataat ttgttataaa tatctcttga
     4861 tataatagca ctcattgagg tcattaatga atcggcagta gacattatgg cagccaatat
     4921 agcagctaag aataatacag atattaaagg tggcaaagta gtcgatatca tttgaggtaa
     4981 aacctgaaca gatgatatat ttggaaataa actaccacca atagctccaa ttattcctat
     5041 agggaaagca agaaataata gtataaatcc tgcaattaca ctacttttaa ctgcattttt
     5101 agcattatca gcacattgat atcttaaaaa actttcataa gaaaatattg agcctaaaac
     5161 taatggtaaa actgtataca taaaatcact aatcgattta tttcctggaa agaatggttc
     5221 ttttaccatt gattgtaaca taagtaaagg gttgtcgcca actaatttta agcttatata
     5281 agctactatt ggcaaaaaca ctatacaaat agcaagttga ataaatgctg atactgcaac
     5341 tccccacatt cctgatgtat aagtatatat aatgataact ataactccta taattacagc
     5401 tatatcataa ggaataccaa atgcagtaga tacagaacca aaagaaatca attgactacc
     5461 cataatagct agtatagata ttggtgttac aagactttga taagctctta aaaatacact
     5521 atgaccatat ctagtttcaa tataatcagc aggtgttata tcacaagata agcttcttaa
     5581 ttttcctgcg aaaaatgcat ttataaagca agctaaagct gcacctatag tagaatacat
     5641 tccaacccaa agtcctcttt cagctcccca ttgaactcca ccaactaagc accctcctcc
     5701 aaaagatgta gcagcaatgg ttgcagctag tataggcaaa ggcagatttc tacctgcgat
     5761 taggaaatcg gatgctgttt taactttttt tgaaaaataa aaaccaatcc atatgtatat
     5821 tgcacacgta acaattaaaa gtaacatagt cttttctcct ttataaaata ttttaataaa
     5881 atatacaaaa tatatttaaa atatatttta tataaaagta gtacgatatt tgttttattg
     5941 gttttagatt aatatagcta taataattta tgatattaga tggaaattac gtaaaaatag
     6001 aaaattgaaa attctgaaat ttttgtatat tgatatttat ctcatagatt cttttttgta
     6061 attgtaacac gcttttattt ttaaatcaat agtacatgta taaaaataaa aggaatttaa
     6121 ataagaaaaa gatattttta atatctggat gtagtataga aatatcttga ataaattatt
     6181 cttgaataaa attataaaaa attaaaatca ctagaaatat gataaaataa tttaaaatac
     6241 gcatttcaat gacatttcaa aacaataaaa taataaaaaa caaacctaaa ttaagtctaa
     6301 atagcttttt agttaatttt agtagtaaaa aataaaactt aaaaagtgtt tgacaattat
     6361 gaattttgag aatataatta aattaaaatt atacacatat aaaaatatac tcctgaatca
     6421 agaatgagat atttaagatt caaaatatat attattatac gtgaataata aaaaagtaag
     6481 aaaattttat aagggagggg tagatgtgag tagtcaagaa agcaaaccaa aaggaaatct
     6541 tatatcaaat tttagagatg atatgagaga ccctaagaaa agagcaatat acacatattc
     6601 aagttctata aacttagcgt acaattttat aggttacttt gtatcaactg ttacaaatat
     6661 ttttttaact gatgtggcaa aacttggtgt aattatggca ggtggtatgc aaattataca
     6721 atctttcata aaaattgctg tagctcctat aacaggtaca gtatttgaca aacaaccatt
     6781 caaaaaagga aagtattatc catggcttag atatgcacca gcagcgttag cattaacata
     6841 tggaatattt ttcatagttc cattaatgaa aataagtcca gcattacttt tacctttgat
     6901 gacagcttta ttattaatag catcttgtgc tcagcaagta gttttcacta taatttatgc
     6961 tatttaccct gtagttgcta agacacctag agaccgagtt ataggctcaa ctactacgaa
     7021 tatatttaaa gaagttggta aattcttagt aggtttttca tatccgttat tattagtttt
     7081 atttgcagat gtattaggtg gagaaggaat gggttattta ggtacctact tattctttgc
     7141 agcaggatgc cttttagtat tttggttttc ttcaacagag ataataaaat ctggagcaga
     7201 agaagaagtt cttcaaaaag aagagaagcc aaagattaaa gcaagtgaaa tggcaaaagc
     7261 tttattcact aatgtaccac ttatgatggc attttgttta gaatttctta tatgtataag
     7321 atctatagga ttaggacctt tggctccata ttattttaaa tatgtaatag aagatgaacg
     7381 tggattagca gtatttttat caatcatgcc tttggtaagt gtagcattca tgtttttcgc
     7441 accagtgttt ataaaaatct gtagagagca aaaactagct tcaataattt ctttttctat
     7501 atgtgcacta tgccacttat tggttgcatg gactccttgg gggaaaacta ctttaggagt
     7561 aactatgttg ctggcaattg gtggaggttt ttcaaatgta gtatcaataa taaatcttaa
     7621 tttctttgcc ggttcttgtg attatgggca ttggaaatca ggaaaagact tacctggctt
     7681 aagtatgtca ctatatccag ttgcaataca agtaggagta ttacttgcaa ctactataag
     7741 aacagtttta atgaactcaa tgggatatca agctgatatg gtagtcacag aagcagttaa
     7801 atcaggtttt ataaatatga tttcttattc tatggcaata cctttaataa tagctgttgt
     7861 tatagcaata ctatatccag taagtgacaa gaaattaaac caaataagag aagagttaaa
     7921 tcaaagaaat gcttagttaa aagaaagtta agtagatggt taatttaagc tattaaagta
     7981 agtagacgca atagcgttta tataaatgaa aatacatata cagagggggc ttttaaaaat
     8041 gatagaaaaa ttattgagaa ataccgtaaa agaattacat caatatgttc caggtgaacc
     8101 aatagaaaaa gttaaggaaa aatatggtgt aaaagaaata ataaaattag cttcaaatga
     8161 aaatcctcta ggaccatcac caaaagcaat agaagctatg attgaaatgt taaaacaagg
     8221 tcaactttat ccagagccag aagctaacga acttagaaga aaattagctg aaaagctaga
     8281 tttaaaacca gaaaatttta ttgttgctaa tggtgcagat aacgttatca ctctaatagg
     8341 tgaggctttt ataaatagag gagatgaagt tatatattgt aacccaacat ttccatcata
     8401 tagaactgca actataaaaa atgaagggat accagtagaa gtacctttaa cagaagatta
     8461 taagtatgat ttacaaggta tattagataa gattacagat aaaacaaaat taatatgtgt
     8521 atgtaaccct aataatccaa caggaacaat tgtggatgat aaagagttag aagaattttt
     8581 aaagaaagtc cctgaaaata ttataactat attggatgaa gcatatatag aatttttaac
     8641 agttcctaat tatgtggatg gacttaagta tgtaagggaa aattataacg ttatagtaac
     8701 aagaactttc tctaaaatat atggtcttgc agggcttaga gtaggatatg gtattgctaa
     8761 agatgagata ataagaactt tatttacagt aaaagagcct ttctctgcaa atcgtgttgc
     8821 tataagtgga gcaacagcag cacttgatga tgaagagttt ataaaagaaa catatgaatt
     8881 aaatagagtt ggaatggctt actttaaaga agagtttaca aaaatgggat ttgatgttgt
     8941 agattcacaa tcaaatttcc tttatgtaga tatgaaaaca gatataccta agttatttga
     9001 agacttgaaa aaaagagggt ttgtaataag accaagtgct acacatgcac gtgtaagtat
     9061 tggaactatg gaagaaaata agaaatttgt agcagtttta aaggaaatat taaatattaa
     9121 aggagagcca agtattggat aatagataga aatattatga aacggggtgt agatatgaac
     9181 ttaaaaataa acgcagagag atgtaaaagt tgtgaatact gcgttatatc ttgtaaaaaa
     9241 ggagcattaa aaatatcaag taagataaac aaagaaggtt atgctcatgt agaagttgat
     9301 gagagtaaat gcatactttg tggaatttgc tatcaggtgt gtccagataa tgtttttgaa
     9361 ataattaaag aagaagcatg tcaagaggct tagaaggagt tgggataata tgaaaaagat
     9421 gtggaagggg aaccacgcca ttgcagaagc agccctaaga ggaggttgtg aattttatgc
     9481 aggatatcca attacaccac aaacagaggt aattgaattt ttatcacata gaatgtctga
     9541 acttggaaga acttttatac agtccgaaaa tgagatggct gctatatata tggtatatgg
     9601 agcatatgca agtggaatga ggtctatgac gagttcttca ggaccaggaa tatctttaaa
     9661 acaagaaggg atttcttact tatgtgcaaa tcattaccct tgtgtaatcg taaatgtaca
     9721 gagatggggg cctggtcttg gctcattgga ctcagcacag acagactatc taagagatac
     9781 tagaggggga ggaaatggag attatcattt gatagtttat gcaccaaaca gtattcaaga
     9841 gactgtagat ttgatgtata actcatttga tgtagcggag aagtacagag tgcctgtcga
     9901 aattttgaca gaagcagctt taggtcaaat gatggaacca gtagaatttc cagagtttaa
     9961 gaagagagaa ggagatttag gctggactta tgatggaagt aatagagacc atgcaaaggt
    10021 tgcagataac caaaagccaa ctttttgtat ggagaaacgt atgagaataa ctgaaaatga
    10081 acaacaatgg gaagattatc aagtagaaga tgcagaatat gtgtttgtag cgttcggtat
    10141 accatcaaga acaactatga atgctgttag aagacttaga gaacaaggtg aaaaagttgg
    10201 aataataaga ccaataacag tatggccttt cccatataaa gcatttgaaa aggtaagtaa
    10261 agatgtaaaa ggatttatct cagtagaatc aacagacaca ggtcaattag tagaagatgt
    10321 tgctttaacc tcaaagaaag tatgtaaaga aaatgtacct gtgtatggtt tatttagtgg
    10381 aaatcatata ccaaaaacat tgcaagtaat ggacacttat agcaaaataa aatctggcga
    10441 aatcaaggag gtgttctaat atggctacag aaaaattaac acctagcgtt gtttcaatac
    10501 caaacaagtt ttgcccaggt tgtggtcatg gaatagtaaa tcgtataata gcagaggtaa
    10561 tagaagaaca tggatatgaa aaaaatcatg tattaacatt aggagttggt tgtgtctgca
    10621 atatgaattt tagctggaat ggtgataaga tgcaaactgc acatggtaga gcttcatcta
    10681 cagctatagg agttaaagta gcacttccag atacattagt aatgacttac caaggtgatg
    10741 gagatgctta tgttataggt ctttctgaaa ctttaaatac agcatataga aatcataatg
    10801 tgactgtatt tgtaataaac aataataatt ttgcaatgac tggtggacaa atgtcatgga
    10861 ccactatgcc gggtcaagtc acaacaacaa gtgtaaatgg aagagatata aagactactg
    10921 gtagtccact gaaagttcct gagatggtgg caaacttctt tgatgtagca tatgtagcaa
    10981 gaggttcagt tcatagccca aaggaaataa ttaatctaaa aaaatatata aaaaatgcaa
    11041 tagaagctca attaaatgga gagggatatt ccttagttga aatattagca ccttgtccaa
    11101 ctaactgggg tgtatcacta gagaaatcta tcaaatggat ggaagaagaa atagtgccat
    11161 attatgctct tggcgaattt aagcaaaggg atggtgaata gttatggaaa aagagctagt
    11221 atttgcaggg tttggtggtc aaggagtttt aactcttggt ctgattgtag ctgagtcagc
    11281 acttgaattg gggaaacaag taacttggat gcctgcatat ggtccaacta tgagaggtgg
    11341 aaaagcctat agtgtagtaa agttttctga tgagagtata ggtgggcctg atatggaaga
    11401 aatagatgtt ttagtagcaa tgaataaacc atctttagat tatataaatt tagttaaaga
    11461 aggtggaaca gtagttatta atacatctgc aatagatgag aatgtaacat taagagaaga
    11521 tataagtgta gttaaaataa attgtcagga attagctcaa aaagtaaaca atccaaaagc
    11581 agcaaatata gtagtacttg gagcattaat tgctaaaaca gggttatttg aaaaagaatt
    11641 agctttaaaa actatgtgtg atttctttga ggaaaaagga aaaggaaagt ttaatgttca
    11701 aaatgaagca gcattcatgg aaggctataa taacgccatt tgataaatta cccttatctt
    11761 aagtgattta tctcaagatt taataatctt tagtgccaag agaaacttca tcttgagata
    11821 aaattcactt aaaatcacaa ctataaacat ataggagcgt gaatttatga gtttggaaaa
    11881 acttattaga ccaaaaagta ttgctatagt aggagtgact gataaacttg gttttggaag
    11941 aagtgcagca cttagtatag taaaaagtaa ggaaacagat agagtatatt atgttaatcc
    12001 caaaagagaa gaattgtttg ggagaaaatg ttataagacg atacaagaag ttccagaagt
    12061 agtagactgt gtagtagtat gtacacctag aaatgtagtt ccatctgtat taaaagattc
    12121 tggagagtta ggaacaaagg cagcagtggt atatgctagt ggatttgcag aggaaggtac
    12181 agaggaaggt acagatttag aaaatcaact tatagaaata tcaaatacat acgatatgaa
    12241 aatattgggt ccaaactgca tggggttgct aaattgtata gataaggtta atctatgggc
    12301 aggaggttct aaatgggatt tagatactaa aaaacctggt ataggaattg taggtcaaag
    12361 tggatttata actgctgaaa ttgtttcaag tgattatttt aatatatctt atggtttttc
    12421 aacaggaaat ggaaatatag ttacactaga agatgcagta gatttccttg tagatgatga
    12481 ttatgcatca gtaatagcaa tttaccttga aggtttaaaa aatcctcaaa aatttataga
    12541 tgctttaaaa agggcagcac aaaaaagaaa gccagtaata atattgaaat caggaaggtc
    12601 agaaaaaggt gctatttctg ctgcttctca tacaggaaat ttagctggtt cgagtaaagc
    12661 ttttgaaagt atttttgaaa aatatggagt aatttctgtg gaaaatttag aacagtttat
    12721 gtgtttagca caagctttta gtgttttaga tggtaattta cctgcaaatt ctaattttgc
    12781 agcaataaac ttctcaggag gagaaaatac tatttgtgca gatttagcag aagaaaatgg
    12841 tgtagaactt gcagaaatat cttctgaaac taaagaagaa atgaaaaaat atcttccagg
    12901 atttgcaaca cctaaaaatc cactagatgc tacaacagca ttattccatg aaaaggatat
    12961 gatagtaggt ttattacata cctttgaaaa ggatgatagt gttggattta ctatggtagg
    13021 tgcaaatata agagatgaag aaaatgaaat gcatgaaacc ctttgtaaag ctgtaagtga
    13081 agctagagaa caaggattga aaaaacctgt gtttgcagtt cctacacttg aaggaaatag
    13141 atatttagat tataggacta gattagaaga taatcaagtg cctataatgt catcagttgg
    13201 aactacattt acttgtttta ataaaatggc taagtttata gattatgatt attcaaaaag
    13261 aactttagaa tttaaagctg ttaagaaaag agagtcaaat aatgtagtag cattatcaga
    13321 attagatagt aagattgaga tgaaaaaata tggagtacca gttccaggac aaggtaatgc
    13381 aaaaagtatt gatgaattag atgaaatctt aaaatatatt aagtatcctg ttgttttaaa
    13441 aataaattct tctgaaatat tgcacaaatc tgatgttgga ggagttaaaa taggaattga
    13501 gaatagagat gaggcagtag atgcatataa tgagatttta actaatgtaa aaaaagcaaa
    13561 accagatgct aatattgatg gtatattagt tcaagaaatg gtagaaagtg gtatagaaat
    13621 tattattggt ataactaatg atgaccaatt tggaccaatg ttattagtcg gtttaggagg
    13681 agtatttgta gaggtattta aagatactac attatatcca ttacctataa atcatgatga
    13741 agctattatg atgcttaaaa aactaaaatc atttaagctt ttaaatggct atagaggaag
    13801 tgagccttgt gatattgatg ctcttgcaga tatgatggtc aagttaggaa aatatgctta
    13861 tgaaaataag gatgaagtca aggaaataga cttaaatcca gtgtttgtat atcctaaagg
    13921 aaaaggcgta tgtgcagtag atgccttaat agttaaatat aaatagttta taagttttgg
    13981 tattcaacca taattaaagc accgactgaa aatcacattt tgtaagttag atagtgtgat
    14041 tttcagtcac cccaaattta atttaaaaat attttaaaat gaaagtatag ttttaagttt
    14101 aattgtgaaa tagcactgta taaacaataa aatactacgt ataaaacgaa taataaaagg
    14161 tgttttaatg ataagaatca atcttgattt tcattaaaac accttcttta ttatattaaa
    14221 aatttttaaa cgttatattg tcacaggtgg gtttgttgga gctgcatatg tacgattagc
    14281 aaattcttgg tcaacaaaga atagaccacc ctctccagca agtttaacac gttttatatt
    14341 gtcttcacaa tttgtttctt cttctgcttg ttcagatata aaccaaagta agaattgaga
    14401 agttctaaag tctgattcag agtttgctac agctgctaag ttgtttatta aagctgtaac
    14461 ctttttttca tgagctaacg tacgctcaag aatatccatt gcagaagtaa agtctgaatc
    14521 tggcattggg atagcatcaa gctgaacctt tcctcctaca ttatgtaagt atttgtaaaa
    14581 aaacatagcg tggtctgtct cttctttata ttgaacataa aaccaattag aaaatccttt
    14641 aagtccttct gcttcaaggt aagaagacat agaaagataa agatacgcag aatataattc
    14701 atggttaatc tgctcattaa gtaatttttc cattttagct gaaatcattt ttatacctcc
    14761 aaattttaaa tgctcttata aaatataata atattaaatg gaaaaatatt caataaaagt
    14821 gtttaaatat tttacatatt taataaaaat ttatactacc attaaaaaaa ttataactta
    14881 caatggctat agagccaatt aatggtgcat ttgctccaaa atttgaatgc cttacactta
    14941 tttttttata tttagaaaaa cttgctgaag cagtcaattt ttttaataat gtattttcta
    15001 taaatgtacc aggtatatta aagtcatagc ctattattat agaactacaa tcaatcaatg
    15061 taagtgtatt aactaatgca tatgatacgt atgtacaaaa ttcatcaagc aaaaacatgg
    15121 caagactatc tttattattt gcctcatcta ttaacttgac taaagaaaaa tctttacagt
    15181 taattaatgg ggagttagga taaatatggc tcaatgattc aattctttta attagattac
    15241 tgacacttgt ataataatct aaacatccat tattaccaca actgcacaat ggtccactaa
    15301 aattaattga tgtatgtcct atttctccac tttgtcctag gttgccagta tgaagtttat
    15361 tttctagaac tagaccagct ccaataccat tcattatgtg taggtatata taatttgata
    15421 tatttttacc taaaccatac attttttctg ctaatgcacc cgaattagca tcatttatca
    15481 aaaatattgg caaatcagac atttctttta taaaatctac tatatttagg tttgatacat
    15541 ttccaaaatc tgggggattt agtatggtac catttatatc atctactgga cctattgaag
    15601 aaataccaat tccaattata tctctcttgt tgattttcat tattttagta aacattcttt
    15661 ttattatatc ttttaaaaca tcatttgata gacatttggg gtaagtttca gaaagttgtt
    15721 ttacaatatt accttttaaa tctgaaataa ttaccttaca tatatttctt cttattagga
    15781 ttccacaaat acaaggcgat atattagaaa tatctaataa aataggttta cgacctgatg
    15841 aatgtgcatt taaagttgat gactctattt ccctaatcat attttcatta ataagttcag
    15901 taactagatt tgataaagtc attttagtaa gtcctgtaga cttagctaaa tcaactctgg
    15961 acataggtgt atttgtagaa agtaatttca atattattaa cttattttta atttttacat
    16021 ctttgatgtt agaaccttgt ttgttactca tcataaatct ccttaaataa agttaagtgt
    16081 tttatttatt ttcaagtata ctatcacctt ataatagagt aacatttttt tacttgaaaa
    16141 tatcattaat tagaatatat cacattatat atcataaaat atataaaaaa atgttagaat
    16201 taaattaaaa gtgaaaagta gattgatata taaatagtaa atacttaatt aaaaaaagat
    16261 aatgatagca ataattattg ttaccaagaa tctactactt caagtgttac cttaggtatt
    16321 taagttgata gtggtttgca cgtaataaac ttgatgtaat atatattctt aataatatcg
    16381 ataaaagatt tacttaaaaa taatatagat tatgtaaaca tataatctat ttattgtata
    16441 caataaaatt tcattttgta aaacagtgaa ttaaatatgt aatatagata tcgattttta
    16501 ttacaaattg ttactaaata taggtacatt agaacaaaaa tctagtaaat tgtaactaaa
    16561 atgtaaattt ttcctttaat ctatacaata ttatggaaac tttttgtaat ttatgatata
    16621 ataacaaata tataattatt aaattataat aaatgactat agcgtagatg taatactatg
    16681 ttatagtcat ttttgaatta aacttgatat atcaaggggg aagaatatga gaacaattag
    16741 aagagtttta gcattaggtt taacattagc tatatttcta ataaatgtac ctaatgtaga
    16801 tgcattaaca tcagatacaa ttaaaggtaa caatatatat gagacggctg gattaatagc
    16861 agataaaaag agttatgata cagcaattat ggtaaatatg gataattcta tagcagatgg
    16921 tctttcagca agtggtcttg caggtgctgt tgatgctcca attttgcttg cacaaaaaaa
    16981 taagatacca aatgaaacaa aacaaagatt aaaaaatgtt aaaaagatat acataatagg
    17041 taaagaatta tcaataagta agtcagtaga aactgaacta aaaaacacag gggcacaggt
    17101 aactagattg ggtggagatg acagaataaa gactagttat agtgttgcta aagaggtaaa
    17161 tggtatcaaa aaagttgatg aagtgatatt aactaatgca tataaaggag aagcagatac
    17221 aataagtgct acacctgtat cagtaagaga tatagctcct atagtactta cagatggaaa
    17281 gagtgtacct ttttcaacaa gcaatgtaaa aacatatgca gtaggtggga gtatatcaat
    17341 gagcactagt ttagttaata aaactaatgc taaaagactt ggtggttcag atagatatga
    17401 tacaaataag aaagttataa aagagtttta tccagatgca tcagaatttt atttgagtga
    17461 tggatatgat ttagtaaatg cacttacagg ttctacaatt gctaaggaaa atccaattgt
    17521 attggtgtca gaaagtagtg ataagtctat attagcagga gcagataaga ttactagatt
    17581 aggttcaata agtgacagtg tgtataataa gtgtgtttct gctgcacaaa ataatggcga
    17641 ttcgtctaca aaaggtgagt cacctatgaa aaatgagaca agcatattag gtcagccaac
    17701 agctagttta gaagcgtgct taaaatgggc aaaatctaaa aaagctaatg atttatttat
    17761 agagttaata ccaatattat atgatactgc tgttcaggaa ggtgttaatc ctgttttggc
    17821 agtagctcaa tctgcaaaag aaactggttt ttgtaatttt ggtggagtat tagatgcatc
    17881 atttaagaat ccttgtggac ttaaaacttc tgtaggaggt tctgatactg ataagaatgc
    17941 ccattcaaga tttgatactt gggaagaagg aatattagct caaattcaac atttatgctt
    18001 atatgcagga caagatggtt acccactttc aaatccagta gaccctagac atgaaaaatc
    18061 tttatttggt aaggctaaaa cagttgaaag tttatctaat aattgggctg gaggtcaata
    18121 tggacaagat ttagtaagaa tgatgggaga aattgaggca acaaaataat tgaagattat
    18181 caaatatcca ataaataagg attgattatt atgaaaaaga gtaatatttt tagtatcata
    18241 tttcctacag tcataatggt gctaatgttt ttaacttttg ctacagatat atttaatatt
    18301 ccagatattc aatctaaaag tatttttgtt gtgggaatgg ttttgatttt tccaatttct
    18361 tttttgatac aagggataat ttgtgtatta aataagacta attggatttt atctcttatt
    18421 gtgtctttag taacttatat agtattaatg tatatatttt taaatgattc tgcatatata
    18481 tatgttttac tttatacagc tttttatatg attggacata taacagctaa actctattac
    18541 aaaattaaga cttttaaaaa ttaaattgaa gtatataaaa gtaacattag gagaagtatc
    18601 cttaatgatt ttctaaaatc agaaataggt gcttctcttt tttgtaaaaa taaaagtatg
    18661 taaataaaat ttaaccatta taattttctt ttaacaaatg tatacaataa acttgttgta
    18721 taattaagat agataaaata aagggaggga taatatgaat ttaatagata atcatattca
    18781 tactaatttt tcaagtgatg gaaaggattc catggaagat acaataaaaa aagctataag
    18841 tattggtgtt agatatttga cttttacaga ccatttagaa catgatgaag atagaggatt
    18901 ttgcataaat tataatgact atgttccagt atttaataag tttaaagaaa aatataaaaa
    18961 ggacatagag ttattactag gtgttgaagt gggttacaga aaacatctaa aaaatgaaat
    19021 agaagaaata ataaattcta atccttttga ttttgtattg tgctcaactc atacaattga
    19081 caatgtacct gttccatcaa aggagtattt taaaggtctt agcaaagaag atgcgtatta
    19141 taaatatttt aatagcatac ttgaaactaa tcgtgaattt ggagattaca atatatatgg
    19201 tcatttggat tatatatcta ggtatggaat atattcagat aatagagtta tatacaatga
    19261 ctttaaagat gttattgatg aggtcttaaa gtcaataatc aataatggga gtggtataga
    19321 gctaaatact tctggttata gatatggatt aaatgctata catccaaatg aagatattct
    19381 aaaaagatat aaagaacttg gaggatttat agttactgta ggttctgatt ctcatagggt
    19441 agaagatata tgtaaagatt ttgatgtggc ctatgatatg cttaagtatc ttgactttaa
    19501 atatgtatct ttatttaaag aaagagaaac ttattttgta aatatagaaa aagttaaatc
    19561 taacaatata gcttagagtg tgttttgaag taaattaatg gatagttaaa aagttaatag
    19621 ttataatatt gtatcctcta gaaaaatact agaggttttt attttgctaa aataactaaa
    19681 tagaattaaa tttaaatagt atagtttatt ttaaattgaa tag
//
LOCUS       DAMJVG010000075        19721 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.075, whole genome shotgun sequence.
ACCESSION   DAMJVG010000075 DAMJVG010000000
VERSION     DAMJVG010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19721)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19721)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19721
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.075"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            83..757
                     /locus_tag="PC512_002868"
     CDS             83..757
                     /locus_tag="PC512_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2442601.1"
                     /translation="MFKIMVVEDDVSLKNIIAKCLTKWGHDVHQIENLENIIEEFKNY
                     NPELVLLDINLPFYDGFHWCNEIRKISKVPIIFISSRNSNMDVIMGVNLGADDYIQKP
                     FSVDVLVAKVNALLRRTYNFVDNNSNQIIHNGVTLDLSTATINYEDNTIELTKNEIKI
                     LHELMKYKGQIVSRNKLMKKLWDNDWFVDDNTLTVNVNRIRSKLNEIGLEDFIETKRG
                     LGYIIS"
     gene            781..1785
                     /locus_tag="PC512_002869"
     CDS             781..1785
                     /locus_tag="PC512_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2442602.1"
                     /translation="MSFKDFLKDKLGFLVYNFTFLIFTVSVIIFSPVDVFLTDTILYI
                     LVVNVVFLFLYLFISYIKKNKFLDKIKNDTFKINMNDIELARCKNEEKIYLNIIKNHQ
                     YQCNNIINNNIEKFEENKEILNMWVHDVKIPIAIIKLILEQNENLIDEKISDDIDSEI
                     FRIENSVEKILYLSRLEDFHKDFLIQEVNIEKIIRNIIKKYSKYFISKKIILDLNNLN
                     FKVLSDEKWLYFIFEQLLSNSLKYSSLGDNISIYCKRTKNYLQLRVEDTGCGIKKEDL
                     NRIFNKGFTGNNGRNNSKSTGLGLYLVKELCDKLGHKIDVDSEYNQYTKFTITFKCDL
                     "
     gene            1897..3126
                     /locus_tag="PC512_002870"
     CDS             1897..3126
                     /locus_tag="PC512_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HDF2442603.1"
                     /translation="MSFLKKFKNKRFRNNSFKSNNFRNSSFGSSGFKSKNKGFKNNPF
                     KNKRFKIYAGIAVIILLILGVLAYVDSKNTELQANENFIETYTIPENEKIFINGMVVP
                     KQTKDFNISGDYELSDVNVTNGQKVNQGDLLFTAKNPTIIAEIDSLKSQLSQYKKQKI
                     SLSDIAENKDAIASINAQITALNSQIASLDKKAYDRVTAPFDGTVYLNDQTGNPDQPV
                     SFMTIQGLEFYMKGQASEQDLPKMKIDQMVNILVFSTDQKLTGRISFISDKPSTPNTE
                     MGAQQNTLSYYDINIAFDNQEGLVNGFHLQASLEVANSSFKIPASCVLKDNKHSYVFK
                     DLDGILKKQIVDVASQNDDFAVVRGGLEQGDIIIKHPTKEMKEGDPVQGDGVTAGSNN
                     GDTTPNKKVEEVTMDVN"
     gene            3134..3808
                     /locus_tag="PC512_002871"
     CDS             3134..3808
                     /locus_tag="PC512_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2442604.1"
                     /translation="MLIKLENIQKYYKVGKDELHVLKSLNLEIESGEFVMIMGKSGSG
                     KTTLLNILGFLDVFDEGRYIFDGTDVTNLSENERSVFRNINIGFVFQQFNLIETLNVY
                     QNVELPLIYNKALKKSNREEIVKDKLSSVGLLDKLKQKPLQLSGGQQQRVAIARCLAN
                     DPQIIFADEPTGALDSETSREIMELLTRLNKQGKTIIMVTHDQDLTKYATKVIRLKDG
                     VFTSEV"
     gene            3811..5043
                     /locus_tag="PC512_002872"
     CDS             3811..5043
                     /locus_tag="PC512_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2442605.1"
                     /translation="MSLLKNSLANLKGHKLRVFVALLWIIIGITSVILVSSIGNGFQK
                     EIKKSVNNVNPNKTTISFESADNTGLTDDMSIFLKPFNAKDLEELSFVEGVERIAPSR
                     DGFNLDSVYSSQASFDKKTTYVDVGPVKKDSKINLICGRDFSLDDEKRKVILLTLQST
                     SEIFENPEDALGHGININGTIFEIIGVLDDSQQNQAGGFFGGYQDMQFTTSLVPKKAF
                     DTLMSQNSYSNEIYQLDLVSSKGYNVNEVANNVIAKLYEMHPGINGSYTTPDPTEQTA
                     YLESINSNVNKYVSIITVVAMFVGGIGVMNIMYVSVMERQREIGIRRAIGAKPRSILF
                     QFLVEAVFITVCGGILGTIVGFAATNYVSKYIGFEAIPSLNSLFYAIVATILTGVVFG
                     LIPAFKASKLDPIKAIYK"
     gene            complement(5329..6594)
                     /locus_tag="PC512_002873"
     CDS             complement(5329..6594)
                     /locus_tag="PC512_002873"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HDF2442606.1"
                     /translation="MILIKNGRVIDPKSQRDENIDLIIKENKIYKIGKFDESDEYEKI
                     IDASGNVVAPGLVDVHVHFRDPGFTYKEDIESGAKSAARGGFTTVICMANTNPIVDNE
                     DTFNYVKEKSKNACINVLQAAAITKGFEGKELVDMEALKKAGVPGFTDDGLPLMDSNL
                     IMEAMIKAKELDVPLSFHEEDPSLVGNPGVNAGKVASELGLKGASSVAEDVMVARDCM
                     LALKTGAKVDIQHISSGVSVDMVRFAKYLGANVVAEASPHHFTLTEEDVLEFGTNAKM
                     NPPLRSKWDRDKIIEGLNDGTIEIIATDHAPHSKEEKDREFIKAPSGIIGLETSLALG
                     ITNLVHKNHLSMMQLIEKMSINPAKLYNLNIGFIEEGAVADIVIFNPEEEWTVESFVS
                     KADNSPFKGKSLYGKVNYTICNGEIVYNA"
     gene            complement(6647..7795)
                     /locus_tag="PC512_002874"
     CDS             complement(6647..7795)
                     /locus_tag="PC512_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HDF2442607.1"
                     /translation="MKSVSVRSCKTYNYEEVKLSIEKNLEDIGGIDKFVKKGSKVLIK
                     PNLLMKKKPEEATTTHPMVVKVVCEKLLELNCDITIADSPGGPYNQSSLKSIYKASGI
                     EEVANELGIKLNYDVSDVKIHSEKAHVLKYMDIIKPIVDSDYIINLCKLKTHIMATFT
                     GGTKNLYGCIAGLKKAEIHYRFPTEELFCENVLLDICDYIKPTLTIMDGIVGMEGDGP
                     SAGTTREIGVLLASQNPYAIDVVACKIISLLPNKVATIRGAIKRGYIQEDFSDIEILG
                     EDIKDLIIKNYKIPNVSKDLRLFSVKLPKFLNEPISKLITPKPVVRFQDCIKCGKCKE
                     ACPASTIEIGTKGAIIDLSKCIRCYCCHELCPKKAIDVKRNFVFKYVK"
     gene            complement(7895..8440)
                     /locus_tag="PC512_002875"
     CDS             complement(7895..8440)
                     /locus_tag="PC512_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH peroxidase"
                     /protein_id="HDF2442608.1"
                     /translation="MKKFVCTVCGYIHEGDAAPAQCPVCKVGADKFEEMKGEMVWADE
                     HRIGVAQGVDAEIIEGLRANFTGECTEVGMYLAMSRQADREGYPEVAEAYKRIAFEEA
                     EHAAKFAELLGEVVVADTKENLRVRVDAEYGATDGKLKLAKRAKELGLDAIHDTVHEM
                     CKDEARHGKAFLGLLNRHFGK"
     gene            complement(8663..9607)
                     /locus_tag="PC512_002876"
     CDS             complement(8663..9607)
                     /locus_tag="PC512_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HDF2442609.1"
                     /translation="MQKNKKEGALLKKYFGEIGLIFIAIIWGSGFVATQFALDGGLTP
                     LQIITLRFFLAAIIMNLLFFKQIRANMGKKLLKAGGILGIFLFLAFTVQTIGLMYTTP
                     SKNAFITAANVVIVPFIGFILYRRKLDKIGIISSLVALIGIGILSLEADFSINFGDFL
                     TLICSFGFAFHIFFTSEFAKDNNPMALTAIQFTVAFLMSVVVQTFAGQLKMEAELSGY
                     MGTMYLAVFSTTIGFLFQTICQKRVDGTRTAIILSTEAVFGTIFSIIILKELITAKLV
                     IGSILIFVAIITAETKLSFLKSKKVKLKDSEESSLESI"
     gene            9993..10874
                     /locus_tag="PC512_002877"
     CDS             9993..10874
                     /locus_tag="PC512_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase"
                     /protein_id="HDF2442610.1"
                     /translation="MVKKRKKKTVTLTILVVIVIGIFSMAWADMSRKKEMKETQERLK
                     AERLEKERIEKEKNEPIIGAKKEAVKEYGYDAKIVWDKLNKYDYSNNGEKIVFLTFDD
                     GPSTTNTPQVLDILKRHGVRGTFFIKGDSLERKGANEILKRTFDEGNAIAHHSYTHDY
                     KKLYPNRSLNLDTFVNELNKTDEAMKKVLGKNFSSNVVRCPGGYMSWKNMEPLGNYLK
                     EKNMASIDWNALNADAEGKKKNAQELFEHAKKSSEGKEMVVLLMHDTYGKQETVNALD
                     QIITYFKDNGYQFKILI"
     gene            complement(10935..12143)
                     /locus_tag="PC512_002878"
     CDS             complement(10935..12143)
                     /locus_tag="PC512_002878"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HDF2442611.1"
                     /translation="MKSIDEQMRIIMKGVDDLIDEKELREKLIKSEKEGKPMIVKLGL
                     DPSAPDIHLGHTVVLRKMKQLQDLGHQIVIIIGDFTGKIGDPTGKSKARKALTTEQVL
                     ANAKTYEEQIFKVLDKEKTIVRFNSEWLAKLNFEDVIKLAATITVARMLEREDFKKRY
                     EGQMPISVHEFFYPLMQAYDSIALEADIELGGTDQRFNLLMGRSLQREFGMESQIVIM
                     MPLIEGLDGKEKMSKSLGNYIGIDEEAGIMYQKSMEIPDELIIKYYNLVTDVHPDEVN
                     KIESQLKEGSVNPRDIKMNLAREIVTLYHGEESAKEAEERFKSVFQKGQIPEDIQTIQ
                     VKEDGFDLIEVLVSNEIVKSKSEVRRLASQGGVKVNGEKVEDLSTIVKESELVVQIGK
                     KKFVKIELVK"
     misc_binding    complement(12216..12468)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(12620..13609)
                     /locus_tag="PC512_002879"
     CDS             complement(12620..13609)
                     /locus_tag="PC512_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2232 domain-containing protein"
                     /protein_id="HDF2442612.1"
                     /translation="MIYGGSVLNTTKKLTEAALLSSLFIVVTIIAVSTGFGYAIYLDF
                     IVPVFFCIICLKCDLKYTILSGITSLLIISLVLGNLGTAIWASQSVLLGIMCGYLINK
                     PTMVMDDLVYGSVFGVIVMVFIDIYASTLIGYSFMKEFQGYSKWIYFNGYTNFIYYLM
                     IALFPFGMVFCIYLLSLILGNKLHILDSNSLKKFLIFKNFRNLNQFLCCSKKAFYICV
                     SYLAIFEVLKLLNVKVDSVYLKTIFISITYISVYFIIRDSCMSLQNFIIAKFRKLLYA
                     RILFLIIILLLFFIFDVTVISLIIINAFLNKKINIRLSQSNIVNKQINLLIEK"
     gene            13761..14201
                     /locus_tag="PC512_002880"
     CDS             13761..14201
                     /locus_tag="PC512_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2442613.1"
                     /translation="MFKIKHFNDLSLDEFYEIAKSRYEVFACEQKIFSLNDYDDIDKS
                     SYHIFLKENGLICAYARIIPKEYSSYNDVSIGRVLVLSSHRRKGLAKQMMDCAIDFIK
                     VNLHENNITLSAQTYIKNLYLSCGFKEISEVYDEAGIEHIKMRL"
     gene            14528..14755
                     /locus_tag="PC512_002881"
     CDS             14528..14755
                     /locus_tag="PC512_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HDF2442614.1"
                     /translation="MKNLNDIQVKKTVKVEDILSSGNLRERMLALGLTRGAVIDVVRK
                     GPKNNLTVYKIRGSKIALRQEESSLILVSDI"
     gene            14781..16901
                     /gene="feoB"
                     /locus_tag="PC512_002882"
     CDS             14781..16901
                     /gene="feoB"
                     /locus_tag="PC512_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HDF2442615.1"
                     /translation="MGLTHNSTKMSSLKDMFDIDNKEDQFVIALAGNPNTGKSTVFNH
                     LTGLRQHTGNWPGKTVATARGNFKYKNTEYALIDLPGTYSLFALSQEEIVARDFICFG
                     NPDAVIVVCDATCLERNLNLVFQVMELTDKVILCINLIDEARKKGITIDKKLLEDSLG
                     IPVILTAARNGSGMDELLDTLNDVSFDKYKLNNKPVRYNENIENVVKSIQPELDNIIP
                     GINSRWLGLRLIDGDESIFESMSNYIDKDSIDAINEVKKKIPDNINKQKIRDEFTKIN
                     YDYAKKLSDECCSNVAKKSTDREEKVDKILTSKIFGLPIMLLLLGTILWITIEGANYP
                     STLLSNLLLGFEPSISGILNSINCPSWLNDMLVLGLYRTLAWVISVMLPPMAIFFPLF
                     TLLEDFGYLPRVAFNLDHLFKKACAHGKQCLTMCMGFGCNAAGVIGCRIIDSPRERLI
                     AILTNNFVPCNGRFPTLIAISTIFFSSVITNSFVSSVATALCITLLIILGVIITLLVS
                     YTLSKTLLKGVPSTFTLELPPYRVPQIGRTLYTSIIDRTIFVLGRAVMVAIPAGVITW
                     IFANIYIGDLSILSHVANFLDPLAKLIGLDGFILLAFILGFPANEIVVPILLMAYLAT
                     GSMIELDSFSALGQVLREHGWTYLTALNVMLFSLLHWPCATTLLTIKKETGSLKWTAL
                     GFLMPTILAFVVCFLTTTVYNLFI"
     gene            complement(17034..17852)
                     /locus_tag="PC512_002883"
     CDS             complement(17034..17852)
                     /locus_tag="PC512_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2442616.1"
                     /translation="MEKQYFTTGEFAKLCGISKQTLIFYDKIGIFSPEYKDKNNYRYY
                     SVYQYDTLDILQSLREIGMSLEEIKEYIQNRTPQLCVKMLKEEEKKIREKIKKLRKIS
                     SKMQNRINITVEGISKMNSEEIYISKKFEEYLVLSSDLSNMSNSDFMMELIDFTNYCK
                     SKNLYQGYELGVIVSNENIKNGDYLSISSFYLKIDKKIKDKKLYVKPEGMYACIKHIG
                     KYEDSYKSYEKLKKYIYENEYKIVGNSYEESILDFFCESNEDNYMTEISIQVSR"
     gene            18059..18343
                     /locus_tag="PC512_002884"
     CDS             18059..18343
                     /locus_tag="PC512_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442617.1"
                     /translation="MLVRVKIVIGATIRYLIKHKVNYCNKKSLDKLELKYGNIDREKA
                     VKLEIFYQYLIELEYIEMSLLIRRLDTAITSLALVSIITIASYYLIRKNV"
     repeat_region   18501..19324
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=18568..18596
                     /rpt_unit_seq="atttacattccatatagttaatataaaac"
BASE COUNT         7062 a         2909 c         2545 g         7205 t
ORIGIN      
        1 taggtaataa ggtagaaata ttttaattta tcaagtagaa tatagttatg ttaatataac
       61 tattttgaat taggaggtaa gaatgtttaa aataatggta gttgaagatg acgtctcatt
      121 gaaaaatatc atagcaaagt gtcttactaa atggggacat gatgttcatc aaatagaaaa
      181 tcttgaaaat ataatagaag agttcaaaaa ctataaccca gaattagttt tattggacat
      241 aaaccttcca ttttatgatg gttttcattg gtgtaatgaa ataagaaaaa tttcaaaagt
      301 tcctataatt tttatttctt caagaaattc taatatggat gtaataatgg gtgtaaattt
      361 aggtgcagat gattatatac aaaaaccttt ttctgtagat gtcttagtag ctaaagttaa
      421 tgccctttta agaagaactt ataattttgt tgataataac tcaaatcaga ttattcacaa
      481 tggtgttact ttagatttat caactgcaac aataaactat gaagataata ctattgagct
      541 aacaaaaaat gaaatcaaaa ttctccatga gcttatgaaa tataaggggc agatagtaag
      601 taggaataaa ctcatgaaaa aattatggga taatgattgg tttgtagatg ataatacatt
      661 aactgtcaat gtaaatagaa tacgctcaaa attaaatgaa attggtttag aagattttat
      721 agaaacaaaa agaggattgg gttatataat cagttaaaac aattctaagt aggtgaattt
      781 atgagcttta aagattttct caaggataaa ctaggttttt tagtatacaa ttttactttc
      841 ttaattttta cagtatcagt tattatattt tctcctgtag atgtttttct gactgatact
      901 attttatata tattagttgt aaatgttgtg tttttatttt tatatctatt tattagctac
      961 atcaagaaga acaaattttt agataagata aaaaatgata cattcaaaat taatatgaat
     1021 gatatagaat tagctagatg taaaaatgaa gaaaaaatat acttgaacat tattaaaaat
     1081 catcaatatc aatgtaataa cataataaat aataatatcg agaaatttga agaaaacaaa
     1141 gagattttaa atatgtgggt acatgatgta aagataccta tagctataat aaaactcatt
     1201 cttgaacaaa atgaaaattt aattgatgaa aaaatttcag atgacataga tagtgaaata
     1261 tttagaattg aaaactccgt tgaaaaaatt ttatatttat caagactcga agattttcat
     1321 aaggattttt taattcaaga ggtaaatatt gaaaaaatca ttagaaatat tataaaaaaa
     1381 tactcaaaat attttatttc aaaaaaaatt attttagact taaataattt gaattttaag
     1441 gttttatctg atgaaaaatg gctatacttc atattcgagc aattattgag taattcccta
     1501 aaatactcct cattaggaga taatatatct atctattgca aaagaaccaa aaattattta
     1561 caattaagag tggaagatac tggttgtggt ataaaaaagg aagatttaaa tcgaatattc
     1621 aataagggat ttacaggtaa taatggaaga aacaattcta aatctacagg tcttgggctt
     1681 tatttagtaa aagaactttg tgataagctt ggtcataaaa ttgatgtaga ttcagagtac
     1741 aaccaatata caaaatttac tattacattc aaatgtgatt tatagtatct tattattgat
     1801 agtttatttt cattaactta tattcaactt cttatagtaa ttctatatgt acatcccagt
     1861 atataattaa gtagttttta taaaaaggag gaagacatgt cttttctaaa aaaatttaaa
     1921 aataaaagat ttagaaataa cagttttaaa agtaacaact ttagaaatag cagttttgga
     1981 agtagtggct tcaagtctaa aaataaaggt tttaaaaaca atccctttaa aaataagaga
     2041 ttcaaaatat atgcaggaat agcagtaatc atacttttaa ttctaggagt tcttgcttat
     2101 gttgattcga aaaacactga attacaagct aatgaaaatt ttatcgaaac atatactatt
     2161 cctgaaaatg aaaaaatatt tataaatggg atggttgttc ctaagcaaac taaggacttc
     2221 aatatatctg gagattatga gttaagtgat gttaatgtta caaatggtca aaaagtaaat
     2281 caaggagacc ttctttttac tgctaaaaat ccaactataa tagcagaaat agatagttta
     2341 aaatcacaac ttagtcaata caaaaaacaa aaaatatcac tttctgatat tgctgaaaat
     2401 aaagatgcta ttgcttctat aaatgcacag ataactgctt taaactctca gatagcttct
     2461 ctggataaaa aagcttatga cagagttact gctccttttg atggcacagt atacttgaat
     2521 gaccaaactg gaaatccaga ccaaccagtt tcatttatga ctattcaagg tctagagttt
     2581 tatatgaaag gacaagcaag tgaacaagat ttacctaaaa tgaagattga ccaaatggtc
     2641 aatatactag ttttttcaac tgaccaaaag cttactggta gaataagttt tatatctgat
     2701 aaaccatcta ctccaaatac tgaaatggga gctcagcaga atacactatc ttattatgat
     2761 ataaacatag catttgataa tcaagaagga ttagtaaatg gattccatct tcaagcatca
     2821 cttgaagtag ctaattcaag ctttaaaata ccagcatctt gtgtacttaa agacaacaaa
     2881 cactcatatg tatttaagga tttagatggt atattgaaaa agcaaattgt agatgtagca
     2941 agtcaaaatg atgattttgc tgtagttaga ggcggtcttg aacaaggcga tataataata
     3001 aaacacccta ctaaagaaat gaaagaagga gacccagttc aaggcgatgg cgtaactgct
     3061 ggttctaata atggagatac tactccaaac aaaaaagtag aagaagttac tatggatgtg
     3121 aattaattta catatgttaa ttaaattaga aaatattcaa aaatattaca aagtagggaa
     3181 agatgaatta catgttttaa aatccttaaa tttagaaatt gaatctggag aatttgtcat
     3241 gataatgggt aagtctggta gtggtaaaac tactttactt aatatcttag gttttctaga
     3301 tgtatttgat gaaggaagat atatatttga tggaacagat gtaactaatt tgagtgaaaa
     3361 tgaacgttct gtttttagaa atattaatat tggatttgtt ttccaacaat ttaatttaat
     3421 agaaactcta aatgtatatc aaaatgtaga gttgcctcta atttacaata aagcactaaa
     3481 aaaatctaat agagaagaaa ttgttaaaga taaattaagt tctgttgggc ttttggacaa
     3541 gcttaagcag aaaccacttc aattatctgg tggtcaacaa cagcgtgtag ccattgcacg
     3601 ttgcctagca aatgaccctc agataatctt tgctgacgaa ccgactgggg cattagatag
     3661 tgaaactagc agagaaatta tggagctttt aacaaggctc aacaaacaag gtaagactat
     3721 aataatggtt acacatgatc aagatttaac taagtatgca actaaggtta tacgacttaa
     3781 agatggtgtg tttacttcgg aggtgtaatc atgagtttat taaaaaattc tttggccaat
     3841 ttaaaaggtc acaagcttcg tgtatttgta gctttactct ggattataat aggaataact
     3901 tcagtaatac ttgttagttc tataggtaat ggatttcaaa aagaaattaa gaaatctgta
     3961 aacaatgtaa accctaataa aactactatt tcgtttgaat cagccgataa cacaggtctt
     4021 actgatgata tgagtatttt tttaaaaccc tttaatgcaa aagatttaga agaattatca
     4081 tttgttgaag gagtagaaag aatagctcct tcaagagatg ggtttaacct tgattcagtt
     4141 tactcttcac aagcatcttt tgataaaaaa actacgtatg ttgatgttgg accagtaaaa
     4201 aaagattcta aaataaattt aatttgtggt agagattttt ctttagatga tgaaaaaaga
     4261 aaagtaattt tacttacatt acaaagtaca agtgaaattt ttgaaaatcc agaagatgcc
     4321 ttaggtcatg gtatcaacat aaatggaact atatttgaaa taataggggt attagatgat
     4381 tctcagcaaa accaagctgg aggattcttt ggaggttacc aagatatgca atttactact
     4441 tccctagtac ctaaaaaggc ttttgacact ttaatgagtc aaaattctta ttcaaatgaa
     4501 atttaccagt tagacttagt ttcttctaaa ggctataatg taaatgaagt tgcaaacaat
     4561 gttatagcta aattatatga gatgcaccct ggtatcaatg gttcttatac tacaccagac
     4621 ccaactgaac agacagctta tcttgaaagc attaattcca atgtaaacaa atatgtatct
     4681 ataataactg tagttgcaat gtttgttggt ggtattggtg taatgaatat aatgtatgta
     4741 tctgttatgg aaagacaaag agaaattggt ataagacgtg ctattggagc aaaacctagg
     4801 tctatattat ttcaattttt agttgaagct gtttttataa cagtatgtgg tggaatttta
     4861 ggaactatag ttggatttgc tgctactaac tatgtttcta aatatatagg ttttgaagct
     4921 atacctagct taaatagctt attttatgca attgtagcta ctatattgac tggagttgta
     4981 tttggtctga ttccagcctt taaagcttct aaactagacc ctataaaggc aatttataag
     5041 tagaaattgt ataaagattt tcgattttta gattagttta tataaaacat acttaaatat
     5101 ataacgcact attatatatg atagattagg aacttaatct ttccaaatat aatagtgcgt
     5161 tctttcataa aaaggattct cttccttact atatctaaat taccaagatg ttatgttcta
     5221 attgttcaaa ctaatacttc caattttgat taatcaatct cattctccta atatacaatc
     5281 ttttactttc aatcattgta cactccgcct taaaaaaata atcttaaatt aggcgttata
     5341 tacaatctcc ccattacata ttgtataatt aacctttcca tataaagatt tacctttaaa
     5401 tggtgaatta tcagctttag aaacaaagct ttcaactgtc cattcttctt ctggattgaa
     5461 tataacaatg tctgctacag ccccttcttc tataaatcca atatttaaat tgtacaattt
     5521 tgcaggattt atagacattt tttctattaa ctgcatcata ctaagatgat ttttatgcac
     5581 caaatttgtt attccaagag ctaaagaagt ttcaagccca ataattccac ttggagcttt
     5641 tataaactct ctatcttttt cttctttact atgaggtgca tggtctgttg ctattatttc
     5701 aatagtacca tcatttaatc cctctataat cttatctctg tcccatttac ttcttagagg
     5761 tggattcatt tttgcatttg ttccaaactc caatacatct tcctcagtca atgtaaagtg
     5821 atgtggtgaa gcttctgcaa ctacatttgc acctaagtat tttgcaaatc taaccatatc
     5881 aacagataca cctgaactta tatgttgtat atcaacttta gcaccagtct ttagtgccaa
     5941 catacaatct ctggctacca taacatcttc tgctacactt gatgcacctt ttaatccaag
     6001 ttctgaagct acctttcctg catttacacc tggatttcca actaaagaag ggtcttcttc
     6061 atgaaaacta agtggtacat ccaactcttt tgccttaatc attgcctcca taattagatt
     6121 gctatccatt aaaggtaatc catcatcagt aaaccctggt acaccagctt ttttaagagc
     6181 ttccatatca actaactctt taccttcaaa acctttagtt atagctgctg cttgtaaaac
     6241 atttatacat gcattttttg acttttcttt aacataatta aaagtatctt cattatctac
     6301 aataggatta gtatttgcca tacatataac agttgtaaat ccacctctag cagcagattt
     6361 agctccactt tctatatctt ctttatatgt aaacccaggg tctctaaagt gtacatgtac
     6421 atccactaaa cctggagcaa ctacattacc actagcatct attatttttt catattcatc
     6481 actttcatca aacttgccta ttttataaat tttattttct tttataatta agtcaatatt
     6541 ctcatctctt tgacttttag ggtctattac tctaccattt ttaattaaaa tcatattatt
     6601 tctcctttat atttttaatt tatatagact catataatat tatacattat tttacatact
     6661 taaatacaaa attacgtttg acatcaatag cctttttagg acaaagttca tggcaacagt
     6721 aacatcttat acatttactt aagtctataa tagcaccctt agtccctatc tctatagtgg
     6781 atgcaggaca agcttccttg cattttccac attttatgca atcttgaaat cttaccacag
     6841 gctttggtgt tataagcttt gaaataggtt catttaaaaa ttttggtagc tttacggaaa
     6901 acaatcttaa atctttactt acatttggaa tcttgtaatt ttttataatt aaatctttta
     6961 tatcttcacc taaaatttca atatctgaaa aatcttcttg tatatatcct ctcttaatag
     7021 cacctctaat tgtagcaact ttatttggaa gtaaacttat aatcttacat gcaacaacat
     7081 ctatagcata tggattttgt gatgctaata aaactcctat ttctcgagta gtaccagctg
     7141 aaggtccatc accttccata cctactatac catccataat tgtcaatgtt ggttttatat
     7201 aatcacaaat atctaaaagt acattttcgc aaaacaactc ttctgtagga aatctataat
     7261 gtatctctgc ttttttcaat ccagctatgc atccatataa gttttttgta ccaccagtaa
     7321 aagttgccat tatatgagtc tttaatttac aaagatttat tatataatct gaatctacta
     7381 ttggtttaat aatatccata tattttagaa catgtgcttt ttcactatgt atcttaacat
     7441 ctgaaacatc ataatttaac ttaatgccca gttcatttgc tacttcttca attccagatg
     7501 ccttataaat gctcttaaga gaactttgat tatatggacc accagggcta tctgctattg
     7561 taatatcaca atttaactct aaaagttttt cacatacaac ttttacaacc ataggatgtg
     7621 tagttgtagc ttcttcaggc ttttttttca ttaataaatt tggttttata agtactttgc
     7681 ttcctttttt aacaaactta tctataccac caatatcctc taaatttttt tcaatagata
     7741 actttacttc ttcataattg taagttttac aactcctaac agataccgac ttcatattat
     7801 ctccatcctt ctatcacaac agtttattta tataatttaa aaaaggagaa accaaagttt
     7861 ctccttttaa tctatgtttt aattgtttta attattattt tccaaaatgt ctgtttaata
     7921 atcctaagaa tgctttacca tgtctagctt cgtctttaca catttcatgt actgtatcat
     7981 gtatagcatc taatcctaat tctttagctc tcttagctaa ttttaatttt ccatcagttg
     8041 caccatactc agcatcaact ctaactctta agttttcttt tgtatctgca actacaactt
     8101 ctccaagaag ttctgcaaat ttagcagcat gttcagcctc ttcaaaagct attctcttat
     8161 acgcttcagc tacttctgga taaccttctc tatcagcttg tctactcatt gctaaataca
     8221 ttcctacttc tgtacactca ccagtaaagt tagctcttaa tccttcgatt atttctgcat
     8281 ctacaccttg agctactcct attctatgtt catcagccca aaccatttcg cctttcattt
     8341 cttcaaattt atcagctcca actttacata ctggacattg tgctggtgca gcatctcctt
     8401 catgtatata tccacatact gtacaaacaa attttttcat aattaatttc ctcccaattt
     8461 tatataatta aatttttatt tttaagttta ataacttgct acaagaatat atatacccca
     8521 gactttatag cttaaacact aaaaataaaa tttatttcct aattaatttt atcactttga
     8581 aacaccagta tcaaccaagt tttgatgtca aatttctaca taatacataa tttatttgat
     8641 taattaggaa atagttgtca tattaaatac tttctaatga agactcctct gaatctttaa
     8701 gtttcacttt tttgctcttt aaaaaagata atttagtttc tgcagttatg attgcaacaa
     8761 atatcaagat actaccaata accaattttg ctgtaataag ctcctttaaa attattatag
     8821 aaaatattgt accaaataca gcctctgtgg ataatattat agctgttcta gttccatcaa
     8881 ctcttttttg acatatagtc tgaaataaaa atccaattgt agtactaaat acagctagat
     8941 acatagttcc catgtaacca gataattcag cttccatctt taattgacct gcaaatgttt
     9001 gaactacaac agacattaaa aacgctactg taaattgaat agctgtcaat gccattgggt
     9061 tgttatcttt tgcaaactca cttgtaaaga atatatgaaa tgcaaatccg aatgaacata
     9121 taagtgttag aaaatctcca aaattaatag agaaatcagc ttctaaagaa agtatcccaa
     9181 ttcctataag agctaccaaa ctacttatta ttcctatttt atcaagtttt cttctataaa
     9241 gtataaatcc tatgaatgga actattacaa cattagctgc tgttataaac gcatttttag
     9301 atggtgtagt gtacataagt ccaatagttt gtactgtgaa tgctagaaat aaaaatattc
     9361 ctaaaatccc tcctgctttt aataattttt tacccatatt ggcacgaatc tgtttaaaaa
     9421 acagtaaatt cataattata gctgccaaga aaaatcttaa agttatgatt tgtagaggtg
     9481 taagcccacc gtctaatgca aattgggttg ctacaaagcc acttccccat ataattgcta
     9541 taaatattag tcctatttct ccaaagtatt ttttcaataa agctccctcc tttttatttt
     9601 tttgcaaaat tataaacccc ctaaacagca agagagtttt tctataagca ttactataaa
     9661 ttaatatagt aaattttttc agtattttaa atctaaattt acatacattt tgagctcaaa
     9721 tttatatcca ctatttaaca gtaatatatt aatcattttt tgtaaacacc tttttaataa
     9781 atttttatat tttttatatt tttttaccta tactaaattt ttttatagat atttttaata
     9841 tatatgatac tttaatatta tgcaaataat gtcatataag ttacacttta gttatcttag
     9901 ttacaacttt gtcggtttac tttttctact ttcttcgata taattataat atatttttga
     9961 tacaattcga caaaaggggg aatgctgtaa ttatggtaaa aaaaagaaaa aagaaaactg
    10021 ttacacttac tatacttgtt gtaatagtta ttggtatttt ttctatggca tgggcggaca
    10081 tgtctagaaa aaaagaaatg aaagaaactc aagaaagact taaagctgaa agattagaaa
    10141 aagaaagaat tgaaaaagaa aaaaatgaac ctattattgg tgcaaaaaaa gaagctgtaa
    10201 aagaatatgg atatgacgca aaaatagttt gggacaaact taacaaatac gactattcaa
    10261 acaatggaga aaagatagtc tttcttacat ttgatgatgg accatctact actaatactc
    10321 cacaagttct agatatcttg aaaagacatg gtgttagagg aactttcttt attaagggtg
    10381 attctcttga aagaaaagga gctaatgaaa ttttaaaaag aacatttgac gaaggaaatg
    10441 caatagccca tcactcttat actcatgact ataaaaaact atatcctaac agaagcctaa
    10501 atctcgatac attcgtaaat gaacttaaca aaactgatga agctatgaaa aaagtcttag
    10561 gaaagaattt ttcctcaaat gtagttagat gcccaggcgg gtacatgtca tggaaaaata
    10621 tggaacctct aggaaactac ttaaaagaga aaaacatggc atcaattgat tggaacgctt
    10681 taaatgctga tgcagaaggt aaaaagaaaa atgcacaaga attatttgaa catgcaaaga
    10741 aatcttctga aggcaaagaa atggttgttc ttttaatgca tgatacttat ggaaaacaag
    10801 aaacagtaaa tgcattggac caaattataa catattttaa agacaatggt tatcaattta
    10861 aaattttaat ataataaaaa agcaagttta ttgaatgtac attttatact caatagactt
    10921 gcttttactt tactctattt tactagctcg atttttacaa attttttctt tcctatttga
    10981 acaactaatt cactctcttt tacaatagtg cttaaatcct ctactttttc accatttacc
    11041 tttactccac cttgagaagc taatcttcta acttcactct tactcttaac aatctcatta
    11101 gaaactagta cttcgattaa gtcaaatcca tcttccttaa cttgaattgt ttgtatatct
    11161 tcaggtattt gacctttttg gaatacagat ttaaatcttt cttcagcttc tttagcagat
    11221 tcttctccat ggtataatgt tactatttct cttgctaagt tcatctttat atctcttgga
    11281 tttactgaac cctctttcaa ctgagattct attttattaa cttcatcagg atgaacatct
    11341 gtcactaaat tgtagtattt aattataagt tcatcaggaa tttccataga tttttggtac
    11401 attattcccg cttcttcatc tattccaata tagttaccta aactcttact cattttttct
    11461 ttaccatcta atccttctat taaaggcatc attattacta tttgagactc cataccaaat
    11521 tctctttgta atgatcttcc cattagtaaa ttgaatcttt ggtcagttcc accaagttct
    11581 atatcagctt ctaatgctat agagtcatat gcttgcatta atgggtagaa gaactcatgt
    11641 actgatattg gcatttgtcc ttcatatctc tttttaaaat cttctctttc taacattctc
    11701 gcaacagtaa tagttgctgc taattttatt acatcttcaa aatttaactt agctaaccac
    11761 tcgctattaa atcttacaat agttttttct ttatctaaaa ctttgaaaat ttgttcttca
    11821 taagtttttg catttgcaag aacttgctct gttgttaaag cttttctagc tttagatttt
    11881 ccagttgggt ctccaatttt tcctgtaaaa tctccaatta ttattactat ttgatgacct
    11941 aaatcttgta attgtttcat ctttctaaga actactgtat gccctaaatg tatatctgga
    12001 gcacttgggt ctagacccaa ttttactatc ataggctttc cttctttttc tgatttaata
    12061 agcttttccc ttaactcttt ctcatctatt aaatcatcta cacctttcat aattattcgc
    12121 atttgctcgt ctatcgattt catttttcat tcctcctaaa atatttatat aatctataat
    12181 ttttattttt ataataaaaa aagctttcat cctcttaaaa ggacgaaagc attgcttacg
    12241 tgttaccacc ttagttcatc aatatctcac gatattaatc tcttagagta caattacata
    12301 tactcgtgta ctataacgtg tactaatccg atatctctta atggttgtta tctttcagag
    12361 atagtgctct gagatgtatt caaactaaat caatttattc catttcacca aactggaact
    12421 ctctgttaaa taaaatctag ccctacttct tctcttcata gcatttatat attcagatta
    12481 tttcatcaat tacaagaaat ttttcttaac ttactcataa tatattatta tttttatatt
    12541 ttgtcaacct tttttattat tatatacatg tttttttaca ttatactact tttttatatt
    12601 ttttaccaat acccaaaatt tatttttcaa tcaaaagatt tatttgttta ttgactatat
    12661 tactctgact caatcttata tttattttct tatttaaaaa tgcgtttata attattaaac
    12721 taataactgt tacatcaaat ataaaaaaca gcaataaaat tattatcaaa aataaaattc
    12781 tagcatataa taattttcta aacttagcta ttataaagtt ttgtagtgac atacatgagt
    12841 ctctaatgat aaaatagaca cttatatagg ttattgatat aaagattgtt tttaaataaa
    12901 cagaatcaac tttaacattc aacagtttta gaacttcaaa aatggctaga taagaaacac
    12961 atatgtaaaa agcttttttt gagcaacata aaaattggtt taaatttcta aagttcttaa
    13021 atattaaaaa tttttttaaa gaattagaat ctaaaatatg caatttattc cctaaaatta
    13081 aacttaataa atatatgcaa aacaccatac caaaaggaaa caatgctatc attaaataat
    13141 aaataaaatt tgtataccca ttaaaataaa tccatttgct atatccttga aattctttca
    13201 taaaactata acctattaat gttgaagcat atatatcaat gaaaaccatt acaataaccc
    13261 caaatactga accatatact aaatcatcca taaccattgt aggcttattt attagatagc
    13321 cacacattat accaagtaat acactctgac ttgcccaaat agcagttcct agatttccaa
    13381 gtaccagaga aattattaaa agcgaagtaa ttccagataa aatggtatac tttaaatcac
    13441 atttcaagca gattatacaa aaaaatactg gcactataaa atctaagtaa atagcatatc
    13501 caaatccagt actcacagct ataattgtta ctactatgaa taaagatgac aataaagctg
    13561 cttcagttaa ttttttagta gtattcaaaa cactgcctcc ataaatcata aattttctaa
    13621 ctaaagtttt gtttttaata tagtatatca ctttttaaaa atatttttaa taaatataaa
    13681 ttttaataaa ggtatttatg ttaaaaatgg tataatgtat cttaatattc agttttttaa
    13741 gatgctagga ggtaattact atgtttaaaa ttaaacactt taatgatttg agtttagatg
    13801 aattttatga aatagcaaaa tcaagatatg aggtatttgc ttgtgaacag aagatatttt
    13861 cattaaacga ttatgatgat atagataaaa gctcttatca catattttta aaagaaaatg
    13921 gattgatttg tgcttacgct agaataattc ctaaagaata cagctcttat aatgatgttt
    13981 ccattggtag agttttagtt ctttctagtc atagaagaaa aggattagca aaacaaatga
    14041 tggattgtgc tatagatttt ataaaagtta acttacacga aaataatata accttatcag
    14101 cacaaactta tataaagaac ctttacttat cttgtggttt taaagaaatc tcagaagtat
    14161 acgacgaagc aggtattgaa catattaaaa tgagattata gtgttgacaa gctaatattg
    14221 ttaatatata atttaagtat aaattaaata ttgaattgat atttaggtat ttgaaaatac
    14281 cttacataga gtcagaaggc ttttgctttc tgactttttt attatcaaaa ttcaataatt
    14341 atatggattc aaagtgttaa tttttattct atattctact ttccccaaaa gtaagaatta
    14401 tacccaactt tgtatgatag gcatcttgcc tatctttttt ttgtaaaagt aacaaggtaa
    14461 taatataatg catagtttaa aataagaaga ttagcccagg ctaaatttca agcatggagg
    14521 tgctattatg aaaaacctta acgatattca agtgaaaaaa actgtcaaag ttgaagatat
    14581 attatctagt ggtaatttaa gagaaagaat gttagcgctt ggtcttacta gaggagctgt
    14641 tatagatgta gttagaaaag gtccaaaaaa taatttaact gtctataaaa tcagaggtag
    14701 caagatagct ctacgacaag aagaaagtag cttaatatta gtttctgaca tttaaaaatt
    14761 tctagcagga ggatattaat atggggttga cacataactc aactaaaatg agttctttaa
    14821 aagacatgtt tgatatagac aataaggaag accagtttgt aattgcattg gctggcaatc
    14881 caaatacagg taaaagtact gtatttaatc atcttacagg acttagacag catactggaa
    14941 actggccagg aaaaactgta gctacagctc gtggtaattt taaatataaa aataccgaat
    15001 atgcattaat agatttacca ggaacatatt ctttatttgc cttatcacaa gaagaaattg
    15061 tagctcgtga ttttatatgt tttggtaatc cagatgcagt aatagtagta tgtgatgcta
    15121 catgtcttga aagaaattta aatttagtat ttcaagtgat ggaacttaca gataaagtta
    15181 ttttgtgtat taatttaata gatgaagcta gaaaaaaagg cattactatt gataaaaaac
    15241 ttttagagga ttctcttggt attccagtta ttttaactgc tgcaagaaat ggctctggta
    15301 tggatgaact attggatact ttaaatgatg tatcttttga caaatataaa ttaaataata
    15361 aacctgttag atacaatgaa aatatagaga atgtggtaaa atcaattcaa ccagaattgg
    15421 ataatattat accaggtata aattctagat ggttgggact tagacttatt gatggcgatg
    15481 aaagtatatt tgaatctatg agtaattata tagacaaaga ttctatagat gctattaatg
    15541 aagtaaagaa aaagattcca gacaatataa ataaacagaa aataagagat gagtttacta
    15601 aaatcaacta tgattatgct aaaaaactga gtgatgagtg ttgttctaat gttgctaaaa
    15661 aatcaactga tagagaagaa aaagtagata aaatattaac atctaaaata tttgggcttc
    15721 caataatgct cttattatta ggtactatat tgtggattac tatagaagga gctaactatc
    15781 catccacttt attatctaat ttattactcg gatttgagcc aagtatttcg ggtatattaa
    15841 atagtattaa ttgtccatca tggttaaatg atatgttggt tttaggatta tacagaacat
    15901 tagcatgggt aatctctgta atgctacctc ctatggcaat attttttcca ttatttaccc
    15961 tacttgagga ttttggatat ttgccaagag ttgcatttaa cttagaccac ctatttaaaa
    16021 aagcttgtgc acatggaaaa cagtgtttga ctatgtgtat gggatttgga tgtaatgcag
    16081 ctggagttat tggttgtagg ataattgact ctccaaggga aagacttata gctatactta
    16141 caaacaactt tgttccttgt aatggtcgtt ttcctacttt gatagctata tctacaatat
    16201 tttttagctc agttataacc aactctttcg tatcaagcgt agcaactgca ctttgcataa
    16261 ctttactgat aattctaggt gttataataa cattgttggt ttcttatact ctttctaaaa
    16321 cgctattaaa aggagttccg tctacattta cattagaact tcctccttat agagttcctc
    16381 aaataggaag aactttatat acctctataa tagatagaac aatatttgtt ttaggaaggg
    16441 ctgtaatggt agccatacct gctggtgtca taacttggat atttgcaaat atatatatag
    16501 gagatttaag tatattatca catgttgcaa actttttaga ccctttagct aaattaattg
    16561 gtcttgatgg ttttatatta cttgctttta ttcttggatt cccagcaaat gagatagttg
    16621 tacctatact tttaatggct tacctagcaa ctggttctat gatagaatta gatagcttta
    16681 gtgctttagg tcaagttctt agagaacatg gatggactta tttgacagct ttaaatgtta
    16741 tgctgttcag tttactgcat tggccttgtg caacaacact tttaacaata aaaaaagaaa
    16801 ctggtagttt aaaatggact gccttaggat tcttaatgcc tactatactt gcttttgttg
    16861 tttgtttttt aacaactaca gtttacaatt tatttatata attagtatta actgacagta
    16921 gacatatatt agagaaacca tttaaaaatt tatatacttt attataaagc atagagatat
    16981 attcaatgat aagtaaaatt acttaacatt tgaatatatc tctattttaa ttcttatctg
    17041 gatacttgga ttgaaatttc agtcatataa ttatcttcat tactttcaca aaaaaagtca
    17101 agtatactct cctcatacga atttccaaca attttatatt cattttcata tatatatttt
    17161 ttcaattttt cgtaagattt atatgaatcc tcatattttc caatatgttt tatgcaagca
    17221 tacattcctt ctggctttac atatagcttt ttatccttta tttttttatc tatcttcaaa
    17281 taaaaacttg atatacttaa atagtcccca ttttttatat tttcattact tactattact
    17341 cccaactcat atccttgata caaatttttc gatttacaat aattggtaaa atctattaat
    17401 tccatcataa aatcactatt actcatatta ctcaaatcgc ttgatagaac taaatattct
    17461 tcaaactttt tggatatata aatttcttca ctattcattt tagaaattcc ttcaactgtt
    17521 atatttattc tattttgcat cttagaactt atctttctta gtttttttat tttttctctt
    17581 atcttttttt cttcttcttt aagcattttc acacaaagct ggggagttct attttgtata
    17641 tactctttta tttcctctaa actcattcct atttctctta atgattgtaa tatatcaagt
    17701 gtatcatatt gataaactga gtaatatcta taattatttt tatctttata ttcaggagaa
    17761 aaaataccta ttttgtcata gaaaattaat gtctgcttag atataccaca caatttagca
    17821 aattcacctg ttgtaaaata ctgtttttcc aagggttata cactcctttt ctttttgttg
    17881 tctatatagt tactatattc tttattattt actaaatcaa gtagttatta ttttagaaaa
    17941 tcaatatggt tttgatttta aagcttaaat atcagttaga tgtcagttat aaatatttta
    18001 cccattccca tcataaaaaa gatatcccct cttaactttt ggatggaata ttatatttat
    18061 acttgttaga gtgaaaattg taataggtgc tacaataaga tatttaatta aacataaagt
    18121 taattattgt aataaaaaat ctttagataa attagagtta aagtatggaa atatagatag
    18181 agaaaaagct gttaaactag aaatatttta tcaatattta atagaacttg aatatataga
    18241 aatgagttta ttaataagaa gattagatac tgcaataaca tcattagcat tagtatctat
    18301 tataacaata gcatcatatt atttaatcag aaaaaatgtg taattatgta agctatttat
    18361 aataaaacac tgataaaatt aataataaaa agataatagg atttctatac tacctttttg
    18421 tttttataat atagtgtaat tttattatat ttttgtatgc taatataact agataatcat
    18481 aagataacac attaaaagaa aattatattc tgtatagtta gtataaaacg taagtaatat
    18541 aaatttatgt aaagcaacaa aagatggatt tacattccat atagttaata taaaacgatt
    18601 tcaaatgatt agaataaaaa tatcagaatt gctatttata ttccatatag ttaatataaa
    18661 actataaagt gttactttta tttattttat tttttacata atttacattc catatagtta
    18721 atataaaacg cattatatgg ctgtgtcatt ttgcattcta ttacatattt acattccata
    18781 tagttaatat aaaacctgct taatgcagaa ttaagagagg aagtgttata agatttacat
    18841 tccatatagt taatataaaa ctggttgttc ctgctccggt gttggtggaa ctggtacatt
    18901 tacattccat atagttaata taaaacgaat atgtatggat aattttttac ttaacatatt
    18961 agcatttaca ttccatatag ttaatataaa acctgctgta atttctgatg aagcttctcc
    19021 actaccacca tttacattcc atatagttaa tataaaaccc ttctttaact cttatcgtat
    19081 ttaaacctct tataacattt acattccata tagttaatat aaaacttttt gtgttaagaa
    19141 gaaaaaagaa attttgataa tatttacatt ccatatagtt aatataaaac cttaaagaaa
    19201 aaatggagga agattaagtg aaaaaattat ttacattcca tatagttaat ataaaactgg
    19261 atttaaataa tcaaaacaac tccggtttaa aaaacattta cattccatat agttaatata
    19321 aaaccccaaa ataaacttag tattttcaac acttacacgt atacaactct cttaaatttg
    19381 cagtgaacga gcaatagtgc aattgataac gcttatcata cactctcaac gccttatatt
    19441 tcaactgtta cgccaaattt tttcacaaat atcgctcact gcaaaattcc tataatttta
    19501 ttatatcata aatatattac ttttgaatat tgataccaat ttataccata ataaaagcaa
    19561 aaaaacgtaa tctatctaca ttagatttaa attctataac ttaaagtttt ttacataata
    19621 tttatgcttg tttaatcaat ctaatatatc attcttgtat attgctttta atagtctttt
    19681 ttcttaaata aatatctatc tgaacaagca tagtttaatt a
//
LOCUS       DAMJVG010000076        19470 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.076, whole genome shotgun sequence.
ACCESSION   DAMJVG010000076 DAMJVG010000000
VERSION     DAMJVG010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19470)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19470)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19470
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.076"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(40..201)
                     /locus_tag="PC512_002885"
     CDS             complement(40..201)
                     /locus_tag="PC512_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442618.1"
                     /translation="MNNFLLNVIAGVIASLIFCLICKVFLKVKSHSTRGKSKSGWEFD
                     FKIKFHKFK"
     gene            complement(542..982)
                     /locus_tag="PC512_002886"
     CDS             complement(542..982)
                     /locus_tag="PC512_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDF2442619.1"
                     /translation="MSNLSAFLSQNAIKVDNVKYVASNRFLDKEGKPVEWELKVLSSE
                     EDEALRRKCTKRVKVIGNNGKHTGQYTSEIDYNSYVAELCVASTVFPDLKDAELQNSY
                     GVMGEAQLLKTMLTAGEYVNYTVKVNEVNGFDTSFEDKVEEAKN"
     gene            complement(1054..1524)
                     /locus_tag="PC512_002887"
     CDS             complement(1054..1524)
                     /locus_tag="PC512_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HDF2442620.1"
                     /translation="MAQTINAKDTVSAKKAECFITIEGKRYNFMQAIDLEAKMEKNKS
                     EVPILGRTTKGNKTTGSTNTGSATFHYNTSIFRELLYRYKETGEDIYFDIQVTNEDPT
                     SAVGRQTVVLKDCNMDSGIITKFDADGEYLDEDMDFTFEDWELVEKFNLLAGME"
     gene            complement(1541..2851)
                     /locus_tag="PC512_002888"
     CDS             complement(1541..2851)
                     /locus_tag="PC512_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath family protein"
                     /protein_id="HDF2442621.1"
                     /translation="MALGGGTFVTQNKILPGSYINFISAKRATSSLSDRGIVAIPLEL
                     DWGIDEDVFQVTSDDFEKYSVKYFGYDYTHEKLKGLRDLFKNIRLGYFYKLNKGVKAS
                     CTIATAKYSGIRGNDLKVTVTTNIDDNAKFDVVTLLDNKKVDTQIAKVITDLQDNDYI
                     TWKKDATLEASAGLVFTGGTNGEAVTGAEYQAFLDKIESYSFNALGCLATTTEIKSLF
                     VEFTKRMRDKVGAKFQTVLYKKSDADYEGVVSVENKIKDIGLVESSLIYWAAGVIAGC
                     DINKSNTNKKYDGEFDVDVNYTQIQLEEALKTGKFIFHKVGDEVHVLEDINTFVSFTD
                     DKNDDFSSNQSVRVLDQIANDIATLFNEKYLGKVPNDKAGRISFWNDVVKHHKELENI
                     RAIEDFKTDDVSVELGNDKKTVIVSDAVKVINAMSKLYMTVSVN"
     gene            complement(2852..3028)
                     /locus_tag="PC512_002889"
     CDS             complement(2852..3028)
                     /locus_tag="PC512_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442622.1"
                     /translation="MNKTLSKEDDYKFTKEQIVNSKKYVNRKDLLNAILKENELYSFS
                     EVEEIINKFMKGVS"
     gene            complement(3021..3458)
                     /locus_tag="PC512_002890"
     CDS             complement(3021..3458)
                     /locus_tag="PC512_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442623.1"
                     /translation="MLNNIIDGISVKLDKSFGEKYTIYSEDVEQGINEPCFFIVPLNP
                     SKTPYPSGRELKKNSFDVHYFPRSEAKNFEINEIAEMLLEELEYIEIDGDLVRGTNMN
                     FEIIDNVLHFFVDYNYFTIKNNDTNKMDTVELFGGLKRGDNFE"
     gene            complement(3451..3876)
                     /locus_tag="PC512_002891"
     CDS             complement(3451..3876)
                     /locus_tag="PC512_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HDF2442624.1"
                     /translation="MARWGSVDFREFKRVCKKMEELTKIDLDKFCKDAARELAARLLG
                     KVIRRTPVDTGFLRQGWNGVAYARSLPVYKQGNNYIIEVVNPTEYASYVNFGHRTKDG
                     KGWVKGQHFLTISEMELQSQVDKIIEKKLLILLKGVFDA"
     gene            complement(3876..4223)
                     /locus_tag="PC512_002892"
     CDS             complement(3876..4223)
                     /locus_tag="PC512_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442625.1"
                     /translation="MVSKTRKAIEMLYRDKCTIVEYQPIKDPVTKRTNNKEVIVLENQ
                     PCKLSYKNIVSATEGKVAKLEQTIKLFISPDIEIKAGSKLIINDKEYVRSGESAIYPN
                     HQEIILELFKDKA"
     gene            complement(4217..4618)
                     /locus_tag="PC512_002893"
     CDS             complement(4217..4618)
                     /locus_tag="PC512_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442626.1"
                     /translation="MENNLIGEIEKRLESLGYILKDGDKWLIGFVREKIENIIKLDCN
                     IKTMPIELKEIEVDMIVGEFLFTKKNMGQLDIESINFEAVEKSISEGDTKVDFAIGSG
                     SQTPEQRFDSLIAYLTTYGKNNILTFRCLRW"
     gene            complement(4628..4861)
                     /locus_tag="PC512_002894"
     CDS             complement(4628..4861)
                     /locus_tag="PC512_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442627.1"
                     /translation="MAQVRKLNRILTIEECKIDDFLEMGYDLIDETGKVVRYGKSLNV
                     KDLIAENNILRSKVESLEEENKQLKEKNKLTKK"
     gene            complement(4861..5760)
                     /locus_tag="PC512_002895"
     CDS             complement(4861..5760)
                     /locus_tag="PC512_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsid protein"
                     /protein_id="HDF2442628.1"
                     /translation="MAALNYAKEYSNVLAQAYPYTLNFGDLYATPNNGRYRWTGSKTI
                     EIPTISTTGRVDSNRDTIAVAQRNYDNAWEPKVLTNQRKWSTLVHPADINQTNYVASI
                     GNITKVYNEEQKFPEMDAYCISKIYADWTALGNTADTTVLTTTNVLEVFDKLMEKMTE
                     ARVPENGRILYVTPVVNTLIKNAKEIQRTVNIKDGGTSLNRQTTDIDTVKIIKVPSNL
                     MKTAYDFTTGWKVGAGAKQIFMSLVHPSAIITPVSYQFSKLDEPTAVTEGKYFYFEES
                     FEDVFILNKKADAIQFVVEGAGA"
     gene            complement(5772..6335)
                     /locus_tag="PC512_002896"
     CDS             complement(5772..6335)
                     /locus_tag="PC512_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage scaffolding protein"
                     /protein_id="HDF2442629.1"
                     /translation="MDWLKELLEGIKIEDNKIDVASLQKSIEKKIKETTITQEDYTNL
                     ETQLNTANETIKKFEGGMTKEDVENLKTTYETDKKTLEETYKKEIEEKDFNYWLGDAF
                     KSVKCRDEIALKAHLDMEALRNSKDRQKAFEEQINPLKQDKDYLFNATLEGEEPKINT
                     ITPGQEPKINDFGFNFTGVRPHENNNK"
     gene            complement(6377..6571)
                     /locus_tag="PC512_002897"
     CDS             complement(6377..6571)
                     /locus_tag="PC512_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015981492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442630.1"
                     /translation="MCILTQVIVVVCVVQIVINCIANLNVGILCNKLKKENKANIDKV
                     SDEILKRVREELNKSLDKSL"
     gene            complement(6594..7220)
                     /locus_tag="PC512_002898"
     CDS             complement(6594..7220)
                     /locus_tag="PC512_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015981491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442631.1"
                     /translation="MTKFKKKPVEVEAFRLGYDIEPEWFIGNSRVCNFMEEKCINGHV
                     SCDLETLEGTMRANKGDYIIQGVKGEIYPCKADIFEMTYQKLEYTATIENLTNYAENL
                     EQGHRYINKDNNKKNKLELSAKLELDTTDFEENIRSATKEIETFNEVVYRLEENLNRV
                     FGKGKLNEIKIKSPTKQLSDEDLEYIREIAYKDIKARFAKEGKIKINY"
     gene            complement(7220..7615)
                     /locus_tag="PC512_002899"
     CDS             complement(7220..7615)
                     /locus_tag="PC512_002899"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442632.1"
                     /translation="MAKFKKKYEEVEAFKWMLGSPNTPRWFYQAFEKGIIWLDESLNS
                     MNRKGQVKKTICIKYGNGVIRANNGDWIIKDSEGKIYSCACGEFEKHYEDLDDEKTKF
                     SDEELECLRRIPLKDSKFTFELIGIKEDE"
     gene            complement(7617..7862)
                     /locus_tag="PC512_002900"
     CDS             complement(7617..7862)
                     /locus_tag="PC512_002900"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442633.1"
                     /translation="MLKLYILSIIVFCTGLYLFKMKIDSNEELTEILKNKKVRRKCNF
                     IFMALFPLLNFILGVIFIISSLLVSNEDMIKNLKGDK"
     gene            complement(7933..8091)
                     /locus_tag="PC512_002901"
     CDS             complement(7933..8091)
                     /locus_tag="PC512_002901"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442634.1"
                     /translation="MKKDKEEIFSSPRWTEIPQAKVVGERTLTEEEVKEAQEIRRKII
                     ERKINNKE"
     gene            complement(8093..9580)
                     /locus_tag="PC512_002902"
     CDS             complement(8093..9580)
                     /locus_tag="PC512_002902"
                     /inference="COORDINATES: protein motif:HMM:NF015461.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HDF2442635.1"
                     /translation="MKHKDYWRKRFEQLEEAQNNKSVKYYLELEKQYKLAMNSIEKDI
                     LAWYNRFAKNEGISLLEAKKLLNTRELEEFKWSVEEYIRHGKENAINQKWMKELENAS
                     ARVHITRLEALKLQIQQQVEVLYGNELDGIDKLMRDIYTSGYYHTAFNVQQGVKVGWS
                     LMSLDTNRINKVISKSWTSDGLNFSERVWGKHRPALVNELHTKLTQSIIRGENPKKLV
                     NDFAKRFNVSKSQAKNLIMTESAFFASASRKDCFNDLDVEKYEIIATLDLKTSNICRE
                     LDGKVFDMKDYQVGITAPPFHPRCRTTTTPWFEDEEGYRTARGEDGKTYYVPSSMKYK
                     EWYEKYINKNIKLSDNEQLAINKYISSDSYKINEKLRRGLPLTSEDKNFISDLDSALD
                     KMPNYKGNVNRSLYFFNEKEKIDFLNKHQIGKEIVYNEYISTSSKGEYNPSGQVELNI
                     ISTNGKDIRKYNPQEAEILFKRNSKFITTDNFEYDGKHYITMKEV"
     gene            complement(9570..11009)
                     /locus_tag="PC512_002903"
     CDS             complement(9570..11009)
                     /locus_tag="PC512_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDF2442636.1"
                     /translation="MLNIYISETDLIKVQLKKESTINLVKVIEHYILKHRPEKYKQGE
                     EYYYGNTDVNNKRRYYLLDGAKVDDFTKVNNKAINNYHKLLVDQKVGYSVGNPIVFNA
                     DDDNLTKLLNDLLGEEFDDTITELYLNASNKGVEWLHPYINRKGEFKYVIIPAEEAIP
                     IWDSKRQRELVAFIRFYYIEDIDGNKIKRVEYYTENDITYFIERGNSFIQEFLYDEYG
                     KMTDIQEGHFRINNKEQGWGKVPFIPFKNNEKCVSDLTFYKSLIDIYDNNISTLADNL
                     DEIQEVIYVLKEYPGTSLQEFIDNIRYYKSIKVDGGGGVDKLEINIPVEAKKELLDRL
                     EKNIIIFGQGVNPESQNTGDKSGVALKFLYSLLDLKCSKTEKKFKKAIRELLWFVCEY
                     LKISGSKSYDYKTVQITFNHSMIINEAEKIDMAAKSTGIVSDETIVSNHPWVEDVNDE
                     LERLKKQEDTQKEYDDLIPNNQDGVIDET"
     gene            complement(11015..12268)
                     /locus_tag="PC512_002904"
     CDS             complement(11015..12268)
                     /locus_tag="PC512_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HDF2442637.1"
                     /translation="MVIEMIVRIDFNPDFKEANFTKKRYRAMKGSAGSGKSVNVAQDY
                     ILKLGDKKYQGANLLVVRKSEATHKYSTYAELTGAINRIYGKQADKYWKTTLNPLEIK
                     SKVTGNSIIFRGVNDAKQREKLKSINFSKGKLTWVWCEEATELMESDIDILDDRLRGI
                     LTNPNLYYQMTFTFNPVSATHWIKRKYFDYKNDDIFTHHSTYLQNRFIDEAYYRRMQM
                     RKEQDPEGYKVYGLGEWGETGGAILKNYVIHEFPTEFEYFDNMRLSQDFGFNHANVVL
                     RIGFKDGELYICNEIYVHEMDTSEIIKIANSKGLEKNIFMYCDSAEPDRIKMWKSAGY
                     KAKGVKKGPGSVKAQIDYLKQLRIHVHPSCTNTIKEIQQWKWKQDERTGLYLDEPVEF
                     MDDAMAALRYSIDNKLKNNGISFLK"
     gene            complement(12246..12935)
                     /locus_tag="PC512_002905"
     CDS             complement(12246..12935)
                     /locus_tag="PC512_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2442638.1"
                     /translation="MNEKADLAHEDYLKGLKYKEIAEKYNVSLSTVKSWATRYWKQKG
                     CNQSKKVATKKRGAPIGNKNATGPPGNKNAEKFGFFSKYLPEETRELIQEISIKDKFD
                     ILWEQITIQYAAIIRAQKIMYVKDKEEMIKEIKKHESTENGEKTEYEFQFAWDRQASF
                     LNAQSRAMSELRSLIKQYDEMIHKDWNLATEEQKTRVEKLKCEVDNLSKDDIGDDELK
                     ISVDYGDRNDS"
     gene            complement(12997..13563)
                     /locus_tag="PC512_002906"
     CDS             complement(12997..13563)
                     /locus_tag="PC512_002906"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442639.1"
                     /translation="MLNQFNEFLGNYINIISVIASFASIAALIISIIAFMESNKQAKL
                     ILKYRRNNENNMAGDYYENGNGYIRLDLNKIDDKSNVYAEIRSNNLVDFVIENKSKIV
                     AKSPILSLKFINMEVDIEENNNFEQINSELRWHPKDNTTIHKGINFRIEQFNFKNCVM
                     LKKEAYIEVVLSADNMETKEFSIPIKAY"
     gene            complement(14007..14225)
                     /locus_tag="PC512_002907"
     CDS             complement(14007..14225)
                     /locus_tag="PC512_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442640.1"
                     /translation="MKCPNCGSENIEQGISTVSESGFVTYRTGLEYNTRFSTKVSKTY
                     SDLCLDCGEIVRTYIKGETDRNWCKDYK"
     gene            complement(14432..14678)
                     /locus_tag="PC512_002908"
                     /pseudo
     CDS             complement(14432..14678)
                     /locus_tag="PC512_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424164.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(15123..15611)
                     /locus_tag="PC512_002909"
     CDS             complement(15123..15611)
                     /locus_tag="PC512_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442641.1"
                     /translation="MDNNINKKELFKKVEGRLHHYKFLSAEIKNLELDIESRENEIFG
                     CKAVGYDEKVSPTYAFNSSVENEIIKKERDITRLKKLKKDKEIEKKKIENALTCLDIR
                     EEHFFKLFYNSRMKNSMVYISLEMNSDRKTCRCVRERLVYKIMDMLYPRIKENELPLF
                     KN"
     gene            complement(15705..16430)
                     /locus_tag="PC512_002910"
     CDS             complement(15705..16430)
                     /locus_tag="PC512_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antA/AntB antirepressor family protein"
                     /protein_id="HDF2442642.1"
                     /translation="MNEIMTNENLRVVADDLVTVYETDTGEKIVFARELHNNLEVKRQ
                     FIDWIEDRIKQYGFKENEDYSVFHKNMKNSTGGRPSKEYVLKLDVAKELAMVQNNNKG
                     REIRRYFIRLEKLLNRTLSNSQLSQINTIVNESLLKMEVKHNIQIEQLKKECSEYYRP
                     TSKTKYDISSYIKERLGISKVNEEFELVKKRTLLVLGADKWEDIPKDVLLNSLNLIDE
                     SIRIIKSERKTNQISFFEKDNFC"
     gene            complement(16445..16852)
                     /locus_tag="PC512_002911"
     CDS             complement(16445..16852)
                     /locus_tag="PC512_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HDF2442643.1"
                     /translation="MKVFLVIDGEPVGKERPRMNSITKRIYTPNKTRDYEELIKWLYQ
                     SKVKYRFTGYIKMTLRCYYSIAKSNSKKVKEQKRNNVLRPSKKPDIDNVVKIIADSLN
                     EIAYKDDTQIVEVVASKYYSDKPRVEVILEDII"
     gene            complement(16978..17319)
                     /locus_tag="PC512_002912"
     CDS             complement(16978..17319)
                     /locus_tag="PC512_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor-like protein"
                     /protein_id="HDF2442644.1"
                     /translation="MANIYCENYNCKNYFEDMCMLERIEINNFKECESYLEGKNELYE
                     LENGYTIHPKDLKMVKSKDYSVEVTHIPTGITVKCRSTNSILKNKNKCLEVLEEELTK
                     INSHLELEDLR"
     gene            complement(17394..17576)
                     /locus_tag="PC512_002913"
     CDS             complement(17394..17576)
                     /locus_tag="PC512_002913"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442645.1"
                     /translation="MNKRIKMKKRLIHKKCDERCVNYDFVISNNLITCNVCIGCKYKE
                     NMDKVCEENYKKLRSK"
     gene            complement(17579..17950)
                     /locus_tag="PC512_002914"
     CDS             complement(17579..17950)
                     /locus_tag="PC512_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442646.1"
                     /translation="MFNIYKVKIKTKRTLEQVRNQSVDFEYSEKGLKNTLKYYNLIDD
                     LKVIVVKFGDEYCLANYNEEDRKIIMEAHYLLEQDEYTGCYINEYERFKKDWENGNCD
                     GEACMVFSDDEIEIIEKLREG"
     gene            complement(17987..18316)
                     /locus_tag="PC512_002915"
     CDS             complement(17987..18316)
                     /locus_tag="PC512_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442647.1"
                     /translation="MKIFLLTILLIIICILANYVKNRIYKKSINNLKYKYSVGEKIIY
                     HQINCYYNRMVGCEILEKCYSTKFRKRNTPLYKVKAYVGDNDTTWVIPEWRIECLATT
                     YGEFPKY"
     gene            complement(18398..19402)
                     /locus_tag="PC512_002916"
     CDS             complement(18398..19402)
                     /locus_tag="PC512_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HDF2442648.1"
                     /translation="MIIHKFIIHVLDKNSDTPILNDFEGRVNQDMVLFFQKKISKVSR
                     DNDIRTAVFNNYSNNLIKKCCEQIIYDESSFLNNSKEIAAYLFDVMKLNATLESCDLA
                     ICLYSQKDEKKVAILKLDYNNSYTHSIEFKDDKFNIQMSKNEINIQETKTVKIAALVG
                     LSGMNDKYHLRVLDKDAEKEEANSKFVTEFLNATKIKDDKYKTKKFKNTAENWITNAL
                     SNDIKQAEDVRSILNYTLREKHEIDINDFVDKTIKDDKLKDSFKEHMEEKGLVEGFSI
                     DKKWVDKKLKKRNIKTDNGFEIKGNLTDFEDPMKYTVRQNQNGSIDIVIKNVTFYEEK
                     "
BASE COUNT         5743 a         3689 c         1932 g         8106 t
ORIGIN      
        1 tctattttgc ggtagagtga agttcataat taaatgaatc tatttgaact tatggaactt
       61 gattttaaaa tcaaattccc agccactttt actcttgcca cgagttgagt ggctttttac
      121 ttttagaaat actttacaaa ttaagcaaaa tattaaacta gcaataacgc cagctattac
      181 attaagtaaa aagttattca tacttcccac ctcctttcat taggaagtag gttttatccc
      241 agtatgaact ccactctata aattgtagat tacatcttct tgctaaaaat attataacat
      301 ataattatta catattttac ctattctata tttatttttt tattttgcta tcttcttcgt
      361 cccctctttc tctctctttc agcttctttc attgcttcct cttcatcttc tatctttata
      421 agtattgagg cggctgctaa cgctctctca ttaacttcta aattcatata ttcacttggc
      481 ttccacttta atttttgaat acaataatga gtgatgctag catcaaaatc gccacctctg
      541 attagttttt tgcttcttct actttatcct caaaagatgt atcaaatcca ttgacttcat
      601 tcacttttac tgtataattg acatactcac ctgctgtaag cattgtcttt aataactgag
      661 cttctcccat tactccataa ctattttgga gttcggcatc ctttaaatct ggaaatactg
      721 tagatgctac acataattca gctacataac tattgtagtc aatttcactt gtatattgtc
      781 cagtatgctt accattgtta ccaatcactt ttactctttt agtacacttt cttcttagtg
      841 cttcgtcttc ttcagatgat aaaactttta attcccattc aactggtttc ccttctttat
      901 ctaaaaatct gttactcgct acatatttta cattatcaac ctttattgca ttttgactta
      961 aaaaagcact taaattactc atattattct aatctccttt tattttaatt tttcatataa
     1021 aaaatacaca tatataattt ataaatgtgt attttactcc attcctgcca ataaattaaa
     1081 tttttctact aattcccaat cctcaaaagt gaaatccata tcttcatcta aatactcacc
     1141 atcagcatca aatttagtaa ttattccact gtccatatta caatctttaa gtactactgt
     1201 ctgtcttcct acagcagatg tagggtcttc atttgtaact tgtatgtcaa aataaatatc
     1261 ctcaccagtt tctttatatc tgtaaagtaa ttctctaaaa atagaagtat tataatgaaa
     1321 tgttgcactt ccagtatttg tactcccagt tgttttattt ccctttgttg ttcttcctag
     1381 aattggaact tcacttttat ttttttccat tttagcctct aaatctatag cttgcataaa
     1441 attatatctt ttaccttcta tagttataaa acattcagct ttctttgcac taactgtatc
     1501 tttagcattt attgtttgag ccatattatc actctcctct ctaattaact gaaacagtca
     1561 tataaagctt actcatagca tttattacct taacagcatc agatactatg acagttttct
     1621 tatcatttcc aagctctaca ctaacatcat cagttttaaa atcttctatt gcccttatat
     1681 tctctaattc tttatggtgt ttaacaacat cattccagaa acttattctt cctgccttat
     1741 cattcggaac tttacctaaa tacttttcat taaataaagt tgcaatatca ttagcaattt
     1801 ggtcaagtac tctaacactt tggttacttg aaaaatcgtc atttttatca tctgtaaatg
     1861 atacaaaagt atttatatcc tctaacacat gaacttcatc tcccaccttg tggaatataa
     1921 atttaccagt ttttaaagct tcttcaagtt gtatttgtgt ataattaaca tcaacatcaa
     1981 actcaccatc atacttttta ttagtattag atttatttat atcgcatcct gctataactc
     2041 cagccgccca ataaattaaa ctagattcta ctaatccaat atctttaatc ttattttcta
     2101 cagacactac accttcataa tctgcatcac ttttcttata tagtactgtt tgaaacttag
     2161 ctcctacctt atctctcatt ctctttgtaa attctacaaa taaactttta atttctgttg
     2221 ttgtagccaa acatcctaaa gcattaaagc tatagctttc tattttatcc aagaaagctt
     2281 ggtactctgc tcctgtcaca gcttcgccat tagttccacc agtaaataca agtcctgcac
     2341 ttgcttctag tgttgcatcc ttcttccaag tgatatagtc attgtcttgt aagtctgtaa
     2401 taacctttgc tatttgagta tctaccttct tattatctaa aagtgttaca acatcaaact
     2461 tagcattatc atctatattt gttgtaactg ttacttttaa gtcatttcct ctgataccac
     2521 tatattttgc tgtggctata gtacaactgg ctttaacgcc tttatttaat ttataaaaat
     2581 atcccaacct tatatttttg aataaatctc tcaaaccttt cagcttctca tgagtataat
     2641 catatccaaa atacttcact gaatacttct caaaatcatc actggttact tgaaatacgt
     2701 cttcatctat gccccaatct aactctaaag gtattgcaac aatacctcta tccgataatg
     2761 aactggttgc cctcttagct gagataaaat ttatatagct acctggtaat attttattct
     2821 gtgttacaaa tgttcctcca cctaacgcca tctagctcac tcctttcata aatttattta
     2881 ttatttcctc tacctctgag aaggaatata actcattttc ttttaaaatt gcatttaata
     2941 agtcttttct atttacatac ttcttagaat taactatttg ctccttagta aacttgtagt
     3001 catcttcttt gcttaatgtt ttattcaaaa ttatcacctc tcttcaaacc accgaataac
     3061 tctactgtat ccatcttatt ggtatcatta ttttttatag taaaatagtt ataatcaaca
     3121 aagaagtgaa gaacattgtc tataatttca aaattcatat ttgtacctct gactaaatct
     3181 ccatcaattt ctatatactc taattcctcc agtagcatct cagctatctc atttatttca
     3241 aaattcttag cttctgaacg agggaaataa tgtacatcaa aagaattttt ctttaattct
     3301 ctcccgcttg gatatggtgt cttgcttgga tttaaaggaa caataaaaaa acaaggttca
     3361 ttaatacctt gctctacatc ctcactataa attgtatatt tttctccaaa tgatttatct
     3421 aactttactg atattccatc tataatatta ttaagcatca aatactcctt taagtaatat
     3481 taataacttt ttctctataa tcttatcaac ttggctttgt agttccatct ctgaaattgt
     3541 taagaaatgt tgtcctttaa cccaaccttt tccatcttta gttctatgcc cgaaatttac
     3601 ataacttgca tattcagtcg gattaacaac ctctataata taattatttc cttgtttata
     3661 cacaggaagc gacctagcat aagccactcc attccatcct tgtcgtaaga atcctgtatc
     3721 aactggtgtt cttctaatta ctttcccaag taatcgtgct gctaattctc ttgctgcatc
     3781 cttgcaaaac ttatctaaat caatctttgt aagctcctcc atctttttac aaactctttt
     3841 aaactctcta aaatcaacac tgccccatct agccattatg ctttatcctt aaataactca
     3901 agtattattt cttgatgatt tggatatata gctgattctc cacttcttac atactcttta
     3961 tcatttataa taagttttga acctgcttta atttctatat ctggagatat aaagagttta
     4021 atagtttgct ctagcttagc tactttccct tctgtagcag aaactatatt tttatatgaa
     4081 agtttacatg gttgattttc taatacaatc acttctttat tgttagttcg ttttgttaca
     4141 gggtctttaa ttggctgata ctcaactata gtacatttat ctctatataa catttctatt
     4201 gcttttctag ttttacttac catcttaagc acctaaaggt taatatatta ttcttaccat
     4261 aagtagtaag ataagctatt aagctatcaa agcgttgttc tggtgtttga gaaccacttc
     4321 ctatagcaaa atctaccttt gtatcacctt ctgatataga cttttctaca gcttcaaagt
     4381 taatgctttc tatatctaat tgacccatat ttttcttggt aaataagaac tctccaacta
     4441 tcatatcaac ttcaatttct ttcaattcaa ttggcatagt ttttatatta caatctagtt
     4501 taataatatt ttctattttt tctcttacaa aacctattaa ccacttatct ccatctttta
     4561 atatatatcc aagactttca agtctttttt ctatttcacc aatcagatta ttttccataa
     4621 ttttcaccta ctttttagta agtttatttt tctctttaag ctgcttattt tcttcttcta
     4681 aagactcaac ttttgacctt aaaatattat tttcagctat taaatctttt acatttaatg
     4741 acttgccata ccttactacc ttaccagttt catctatcaa atcatatccc atctctaaga
     4801 aatcatctat tttacactct tctatggtta atattctatt taatttcctt acttgtgcca
     4861 ttatgctcca gctccttcaa caacaaattg tattgcatca gcttttttat ttaatataaa
     4921 tacatcctca aaactttctt caaagtagaa gtattttccc tctgtaactg ctgttggttc
     4981 gtctaactta gagaactgat aagaaacagg tgtaattatt gcacttgggt gaactaagga
     5041 cataaagatt tgtttagctc ctgcgcctac tttccatcca gttgtaaaat catatgcagt
     5101 tttcattaga ttagatggta ctttaattat tttaactgtg tcaatatctg tggtttgtct
     5161 atttaaagaa gttccaccat cttttatgtt tactgttctt tgtatctctt ttgcattttt
     5221 gataagtgta tttactactg gagtaacata caatattctt ccattttcag gtactctagc
     5281 ttctgtcatt ttttccatta acttatcaaa tacttctaat acgtttgttg ttgtaagaac
     5341 agttgtatct gctgtgttac ctaatgcggt ccaatcagca tatattttag atatacagta
     5401 agcatccatc tctggaaact tttgttcctc attatatact tttgttatat tgcctattga
     5461 agccacataa ttagtttggt ttatatctgc tggatgaacc aacgttgacc atttcctttg
     5521 attagttaat accttaggtt cccaagcatt atcatagttt ctttgagcta ctgctattgt
     5581 atctctgttt gaatctactc ttccagttgt agatatagtt ggtatttcta ttgttttaga
     5641 accagtccat ctatatcttc cattatttgg tgttgcatac aaatccccga agtttaaagt
     5701 ataaggatat gcttgtgcta aaacatttga atattctttt gcataattta gtgctgccat
     5761 tttatttcct cctatttatt attattttca tgaggtctta ccccagtaaa attaaaacca
     5821 aaatcattta tcttaggctc ttgccctggt gttatagtat ttattttagg ttcttcacct
     5881 tctagtgttg cattaaacaa ataatcttta tcctgtttca aagggtttat ttgctcttca
     5941 aaagcttttt gtctatcttt actatttctt agtgcttcca tgtctaaatg agcttttaat
     6001 gctatttcat ccctacattt aacagactta aaagcatcac ctaaccagta attaaagtct
     6061 ttttcttcaa tttctttttt gtaggtttct tccaaagttt tcttatcagt ttcataagtt
     6121 gtttttagat tctctacatc ttcttttgtc atacctcctt caaacttttt aatagtttca
     6181 ttagctgtat taagctgtgt ttcaagattt gtataatctt cttgagtaat tgtagtctct
     6241 tttattttct tttctataga cttttgtaaa gaagctacat caatcttgtt atcctctatt
     6301 tttattcctt ctagcaattc ttttaaccaa tccattttaa atgtctcctt tcatttttta
     6361 caaaataaaa aagtccttat agacttttat ctaatgattt atttaattct tctcttactc
     6421 tctttaaaat ttcatcagaa actttatcta tattagcttt attttctttt tttaatttat
     6481 tacaaagaat acctacatta agattagcaa tacaattaat aacgatttgt actacacaaa
     6541 ctacaactat aacttgagtt aatatacaca ttaaaatcat cttccttttt tatctaataa
     6601 tttatcttaa ttttaccttc tttagcaaaa cgtgctttta tatccttata tgctatctct
     6661 cttatatact ccaaatcctc atcagaaagt tgctttgtag gactttttat ttttatttca
     6721 ttaagctttc cttttccaaa tactctattt aaattttctt ctaatctata tactacttca
     6781 ttaaatgttt caatttcttt tgtagcactt cttatatttt cctcaaaatc tgttgtatct
     6841 agttctaact tagctgaaag ttctaattta tttttcttgt tgttatcttt attaatgtat
     6901 ctatgtcctt gttctaaatt ttcagcatag tttgttaagt tttcaatagt tgcagtatat
     6961 tctaattttt gatatgtcat ttcaaatata tctgctttac atggatatat ttctcctttt
     7021 acaccttgta taatgtaatc ccctttatta gctctcatag taccttctaa tgtctctaaa
     7081 tcacaactta catgtccatt aatacatttt tcttccataa aattacaaac tctactattt
     7141 ccaataaacc attctggttc tatatcatag cctaatctga aagcttccac ttcgactggt
     7201 ttctttttaa atttagtcat tattcatcct ccttaattcc tataagttca aatgtaaatt
     7261 ttgagtcctt taatggtatt cttcttaaac attctaattc ttcatcagaa aactttgttt
     7321 tttcatcatc taaatcctca taatgctttt caaattcccc acatgcacaa gaatagattt
     7381 taccttcact atcttttata atccaatctc cattatttgc tctaataact ccatttccat
     7441 actttataca gatagttttc tttacttgac ccttacgatt catagagttt aaagattcat
     7501 caagccatat aattcccttc tcaaaagctt gataaaacca tctaggagtg tttggacttc
     7561 ctaacatcca tttaaaagct tctacttcct catatttctt tttaaattta gccatattac
     7621 ttatccccct ttaaattttt aatcatatct tcattgctaa ctagtaaaga agatatgata
     7681 aatatcacac ctaaaataaa attaagtagt ggaaataaag ccataaaaat aaaattacac
     7741 tttcttctta cttttttatt tttaagaatc tcagtcaatt cctcattact atcaatcttc
     7801 attttaaata aataaagccc tgtacaaaac acaattattg ataaaatata taatttaagc
     7861 atttcaaatc accctctcag taaacttttg cataataaaa gcacctacta attagtcatt
     7921 tagcaagtgc ttttattctt tattattaat ctttctttca attatttttc ttctaatttc
     7981 ttgtgcttct ttcacttctt cttctgttaa tgttctttcc cctaccactt tagcttgtgg
     8041 tatttctgtc catcttggtg atgaaaatat ttcttcttta tcctttttca tattatacct
     8101 ctttcattgt tatataatgt ttgccatcat attcaaaatt atcagtagtt ataaatttac
     8161 tattcctttt aaataaaatc tctgcttctt gaggattata ttttcttata tccttgccat
     8221 ttgtgcttat aatatttaat tcaacttgac cgcttggatt gtattcccct ttactagatg
     8281 tagatatata ttcattatat actatttcct tacctatttg atgtttattt aaaaagtcta
     8341 ttttttcttt ttcattaaag aaatacaagg acctattcac atttccctta taattaggca
     8401 tcttatctaa tgcactatct aagtcactta taaaattttt atcttcactt gttaatggta
     8461 accctcttct aagcttctca ttaattttat aagaatcact acttatatat ttattaattg
     8521 caagttgttc attatctgat agcttaatgt ttttattaat gtatttctca taccattctt
     8581 tatacttcat gctagatgga acataataag tttttccatc ttctcctctt gctgttctat
     8641 atccttcttc atcttcaaac caaggagtag ttgttgtacg acatctagga tgaaagggtg
     8701 gagctgttat cccaacttga taatccttca tatcaaatac ttttccatct aactctctac
     8761 atatatttga tgtttttaaa tctagtgtgg caataatctc atacttttct acatctaaat
     8821 cattaaaaca atcttttctt gaagctgatg caaagaaagc tgattcagtc attattaagt
     8881 tcttagcttg tgacttagat acattaaatc tcttagcaaa gtcatttact agcttctttg
     8941 gattttcacc tctaataatt gattgagtta gcttagtatg taattcattt actaaagcag
     9001 gtctatgctt accccaaacc ctttcactga agtttaatcc atcactagtc caagacttag
     9061 aaataacttt atttattctg ttagtatcaa gactcattaa actccaacca acctttactc
     9121 cttgttgaac attaaaagct gtatgatagt atccacttgt ataaatatct ctcattagtt
     9181 tatcaatacc atcaagttca tttccatata aaacttctac ttgttgctgt atttgtaact
     9241 ttaaagcttc aagtcttgtt atatgaactc ttgcactagc attttctaac tctttcatcc
     9301 acttttgatt tatagcattt tctttaccat gtctaatata ctcttcgaca ctccatttaa
     9361 actcttctag ttctcttgta tttagtagtt tcttagcttc taataaagat attccttcat
     9421 ttttggcaaa tctgttgtac catgctaata tatctttttc tatactattc atagctagtt
     9481 tatattgctt ttctaattca agataatatt ttacactttt gttattttga gcttcttcta
     9541 attgttcaaa tctctttctc caataatctt tatgtttcat ctataacacc atcttgatta
     9601 ttaggaatta aatcatcata ctctttttga gtatcttcct gttttttaag tctctcaagt
     9661 tcgtcattaa catcctcgac ccaaggatgg ttagaaacaa tagtttcatc tgatacaatt
     9721 ccagttgatt tagctgccat atctatcttt tcagcttcat ttattatcat agagtgatta
     9781 aaagtaattt gaactgtttt ataatcatag ctcttactac cacttatctt taaatactca
     9841 catacaaacc acaaaagttc tctaattgct tttttaaact tcttttcagt tttggaacat
     9901 tttaagtcaa gtagtgaata taaaaattta agtgctacac ccgatttgtc acctgtgttt
     9961 tgagattctg gattaactcc ttgaccaaag ataattatat tcttttccaa tctatcaaga
    10021 agctcctttt tagcttcaac tggtatattt atctctagtt tatcaactcc acctccacca
    10081 tctactttaa ttgatttata gtatcttata ttatctataa actcttgtag acttgttcct
    10141 ggatattctt ttaatacata aataacctct tgtatttcat ctaagttatc tgctagtgta
    10201 gaaatattat tgtcatatat atctattaat gatttataga aagttaaatc tgagacacac
    10261 ttttcattat ttttaaaagg tataaatgga actttacccc atccctgttc tttgttattt
    10321 attctaaaat gaccttcttg tatatcagtc atttttccat attcatcata taaaaattct
    10381 tgaataaaac tattacctct ttcaataaag taagttatgt cattttctgt gtagtactca
    10441 actcttttta ttttatttcc atctatatct tcaatataat aaaacctaat aaatgcaact
    10501 aattccctct gtcttttact atcccaaata ggaattgctt cttcagctgg aattattaca
    10561 tatttaaact caccttttct attaatatat ggatgtaacc attcaacccc tttattacta
    10621 gcattgagat atagttctgt tattgtatcg tcaaactctt ctcctagtaa gtcatttaaa
    10681 agcttagtga gattatcatc atctgcatta aatactatgg gatttccgac actatagcct
    10741 accttttggt caactaaaag cttatggtag ttgttaattg ctttattatt aactttagta
    10801 aaatcatcaa ccttagctcc atctaagaga taatatcttc tcttattgtt tacatcagta
    10861 ttaccataat agtattcttc tccttgttta tatttttctg gtctatgctt taagatgtag
    10921 tgttctatga cttttactag gttaatggtg ctctcttttt ttaactgaac ttttattaaa
    10981 tctgtttcac ttatataaat atttaacacc tcctttactt taagaagctt attccattat
    11041 ttttaagctt attatctata gaatatctaa gagcagccat tgcatcatcc ataaactcaa
    11101 ctggttcatc aagatataat ccagttcttt cgtcttgttt ccatttccat tgttgtattt
    11161 cttttatggt attagtgcaa ctaggatgta catgtattct taattgtttc aaataatcta
    11221 tttgagcttt aacacttcct ggtccttttt taactccttt agctttatat cctgcactct
    11281 tccacatctt aattctatct ggttcagcac tatcacagta cataaatata ttcttttcta
    11341 aacctttact gtttgcaatc tttattattt cagatgtatc catttcatgt acatatattt
    11401 cgttacatat atataactct ccatccttaa aaccaattct gagtactaca tttgcatgat
    11461 taaagccaaa gtcttgtgac agtctcatat tatcaaagta ttcaaattct gtaggaaatt
    11521 catgtataac atagttttta agtattgctc caccagtttc tccccattct ccaagaccat
    11581 agactttgta cccttctggg tcttgctctt ttctcatttg cattcttctg tagtaagcct
    11641 catctatgaa tctattttgt agataagtac tatgatgagt aaatatatca tcatttttat
    11701 agtcaaagta ctttcttttt atccaatgag tagctgagac tggattaaat gtaaatgtca
    11761 tttgatagta taggttagga ttagttaaaa tacctcttaa acggtcatct agtatgtcta
    11821 tgtcactttc cataagttct gtagcttctt cacaccaaac ccatgttaat tttcctttcg
    11881 agaagttaat tgattttaat ttttctcttt gttttgcatc attaactcct ctgaaaatta
    11941 tagagttacc agtaacttta ctcttaattt ctaaaggatt taaagtagtt ttccaatact
    12001 tatcagcttg tttaccataa atacgattta tagctcctgt aagctctgca tacgttgaat
    12061 acttatgtgt agcttctgac tttctaacta ctaatagatt agctccttga tacttcttat
    12121 ctcctaactt tagtatatag tcttgtgcta cattaacaga ttttccactc cctgctgaac
    12181 ctttcattgc tctgtatctt tttttagtaa aattggcttc cttgaaatct ggattaaaat
    12241 ctattctaac tatcatttct atcaccataa tctacactta ttttcaactc atcatctcca
    12301 atgtcatctt tacttaggtt atcaacttca catttcaact tctcaactct tgttttctgc
    12361 tcctctgtag ccaaattcca atccttatga atcatttcat catactgttt aattaaactt
    12421 ctaagttcac tcattgctct actctgtgca ttaagaaaag atgcttgcct atcccatgca
    12481 aattgaaatt catactctgt cttctctcca ttttctgtac tttcatgttt cttgatttcc
    12541 ttaatcattt cttctttgtc tttaacatac attatctttt gcgctcttat tattgctgca
    12601 tattggattg ttatttgctc ccaaagaata tcaaatttat cttttataga tatttcttgt
    12661 atcaattctc tagtttcttc gggtagatac tttgagaaga aaccaaactt ttcagcattt
    12721 ttattacctg gtggaccagt agcgttttta ttacctatgg gtgcacctct ctttttggtt
    12781 gcaacttttt ttgattggtt gcaacctttt tgtttccagt atctagttgc ccatgatttt
    12841 acagtcgata aacttacatt atacttttca gctatttcct tgtacttaag cccttttaag
    12901 taatcttcat gggctaaatc tgccttttca ttcataccac cacctcgttt gtttgtcgtt
    12961 ttgggaacaa aaaaagaact ctggttattg agttctttaa tacgctttta ttggtatact
    13021 aaattctttt gtttccatat tatcagctga taatactact tctatataag cttctttttt
    13081 aagcataaca caatttttaa aattaaattg ctctattcta aaatttattc ctttatgaat
    13141 tgtagtatta tcttttggat gccatctaag ttcactattt atttgttcaa agttattatt
    13201 ttcttcaata tctacttcca tattaataaa tttcaaactc aatataggac tttttgcaac
    13261 aatcttactt ttattttcta ttacaaaatc aactaagttg ttactacgaa tttcagcata
    13321 aacattagat ttatcatcta tcttatttaa atcaagtcta atatatccat tgccattttc
    13381 ataataatca ccagccatat tattctcatt atttcttcta tattttaata tcaatttggc
    13441 ttgtttatta gattccataa aagctataat tgatataatc aaggctgcta ttgatgcaaa
    13501 ggatgcaatt acagaaatta tatttatata gttaccaaga aattcattaa actgattgag
    13561 catatttttt ctccttaaaa acattacctt atcttattat atttgtataa tattttttac
    13621 atttactttt aatttattac acaaacttcc tacataaaaa aagaccatct ataaagacga
    13681 ttctctagac taagtatcta tgtttttgct tgtactctgt aacagcatca tttcatgctt
    13741 cttgctctct tattcctttt tctctagcaa ttctttgtgc tatctttcta actaattcag
    13801 cactttttaa tattcctata ctaaccactt ccttatctct attctacatt ataccatata
    13861 ataaagaata aagctaattc ctattaagtt ctgttactct gtttcacaag ttcaaaacct
    13921 taaccctata acatatttat cattatcttt ttaatttatt gcataaaaaa gaccatctat
    13981 aaagatagtc taaatcttat gtatttttat ttataatctt tacaccaatt cctgtcagtc
    14041 tcccccttta tataagttct aactatttca ccacaatcta agcataagtc agaatatgtt
    14101 ttagatacct tagtggaaaa tcttgtattg tattctaaac cagttctata tgtaacgaat
    14161 cctgattcac taactgtaga aataccttgt tctatatttt cgctaccaca attaggacat
    14221 ttcatattta taccccctaa caattacttt ctttcatatt accataatat ataaaagtaa
    14281 tcttttaatt ttatttcttc attacactag ttatccaata tccaatacaa taagacatag
    14341 aataatatga taaatacaat gccatttcag tactatcaaa tcttagatac atcatgataa
    14401 caactgaacc taaaagtgat attaaagctg gaattttcca atctatttgt tttttagcac
    14461 atattatacc attaactaaa aatgaaactg gtatatacaa tactacacct gaaataagga
    14521 ttccttttat atccatctca cttaatccta aactattagt tattgtattt tcaaatgata
    14581 gaaaaaatat tataatcatt gttaataatg gtagcaatac tcctaagata tttttcttca
    14641 tagttatcac ccctaattca tttagtacat tttaccacaa acttaaccta gaaaatataa
    14701 aagacctaga aattaatcta agtcttttta gtgggggata catattcttt aagggagcaa
    14761 gttctaagaa tcgaacttag actaaacacc agtacctgca tgggagtgag gttaccaagc
    14821 cccactcggt ttttagactc tgaattaaga taaaattgta tgagatttta gtcttaattc
    14881 aactgctaca tatagtgtat taataggttt tgaacatagt tagaattgaa cttacagcgt
    14941 cctcacgccc tgcctagtct gttcatattg ctagattagc cctttaaact aacctagcaa
    15001 ttatttagtt ttgagaggga aatctttatt tccacgatat tattatctca tgctttttta
    15061 atcaaaaagg ggagaaagta gggaataaag tgggaatttc tggggaaaaa ctggggaatt
    15121 ttctaatttt taaataatgg tagttcattt tccttaattc ttggataaag catatccata
    15181 attttataca ctaatctttc cctcacacat ctacatgttt ttctatctga gttcatctct
    15241 aaggatatat aaaccatact atttttcatt ctgctattgt aaaacagttt aaaaaaatgt
    15301 tcttctctta tatctaagca tgtaagtgca ttttctattt tcttcttttc aatttcctta
    15361 tcttttttca gttttttcaa tctagtaata tctctttctt tttttataat ctcattctcc
    15421 acacttgaat taaaagcata tgttggactt actttttcat catatccaac agccttacac
    15481 ccaaatatct cattttctct actttctata tctaattcaa gatttttaat ttctgcactt
    15541 aaaaatttat aatgatgtag tctaccttct acttttttaa atagttcttt tttattgata
    15601 ttattatcca tacttccaca ctcctgttta tgttataata atcttggata aaagctttat
    15661 atttttgaca agtggagtgt gaaagcactc cttttttctt tttattaaca gaaattatct
    15721 ttttcaaaga aactaatttg atttgttttt ctctcagatt ttataattct gattgattca
    15781 tctattaagt ttaatgaatt aagtaataca tctttcggga tatcctccca tttgtcagca
    15841 cctaatacca atagagttct tttcttaact aattcaaatt cttcattaac ttttgatata
    15901 cctagtcttt cttttatata agaagatata tcatatttag ttttagaggt tggtctataa
    15961 tattctgaac actctttttt aagttgctct atttggatat tatgtttaac ttccatctta
    16021 agtaatgatt cattcacaat agtattaatt tgactaagct gtgaatttga taaggttcta
    16081 tttagtaact tttctaatct tataaaatat cttcttattt ctcttccttt attattgttt
    16141 tgtaccatag caagttcttt tgctacatca agcttcaata catattcttt tgaaggtctc
    16201 ccaccagttg agtttttcat atttttgtga aaaactgaat aatcctcatt ttccttaaac
    16261 ccatattgtt taattctatc ttcaatccag tctataaact gtctcttaac ttctaaatta
    16321 ttatgtagtt ctcttgcaaa aactattttc tctcctgtat cagtttcata aactgtaact
    16381 aaatcatctg ctacaactct taaattttca tttgtcataa tctcattcat atttatagtc
    16441 ctccttaaat aatatcttct aatataacct caacccttgg cttatcacta tagtatttac
    16501 tagctacaac ctcaacaatc tgtgtatcat ctttataagc tatctcattg agtgaatcag
    16561 ctataatctt aacaacattg tcaatatcgg gttttttact aggtcttaac acattatttc
    16621 ttttctgctc cttaaccttt ttactgttac ttttagctat agagtaataa catcttaaag
    16681 tcatttttat ataaccagta aaacgatact tcactttaga ttgatacagc cattttatta
    16741 actcctcata atctctagtt ttattaggtg tatagatcct tttagttata gagttcattc
    16801 taggtctttc tttgccaact ggttctccat ctattacaag aaaaactttc attttttcac
    16861 cttcttagcc ttcttcctac attctttaca acaataaaca tccttagatt tttcttcaag
    16921 ataaaataac ttaccacacc aactgcatct tcttcgtttc ataagctcac ttcctattta
    16981 gcgtaaatct tctagctcta agtgagagtt tatttttgtt agttcttctt ctagaacttc
    17041 caaacactta tttttatttt ttaaaatact atttgtagaa cggcatttta ctgtaatacc
    17101 agttggaata tgagtaactt caacagaata atctttactt ttcaccattt tcaaatcttt
    17161 aggatgtata gtatatccgt tttctaattc atatagctca tttttacctt caagatagct
    17221 ttcgcattct ttgaagttat taatttcaat tctttcaagc atacacatat cttcaaagta
    17281 gtttttacaa ttataatttt cacaatatat attagccatt taacgcactc cttttataag
    17341 tcaagcctat aacattctag tttcattcac aaacttacct tgactatttt attctattta
    17401 cttcttaatt tcttatagtt ctcttcacat actttatcca tattttcttt gtatttgcat
    17461 cctatacaca cattacaagt tataaggtta ttgctaatta caaagtcata gttgacacat
    17521 ctttcatcac actttttatg aattaatctt tttttcattt taattctttt attcatattt
    17581 aaccctccct tagcttctca attatctcaa tttcatcatc tgaaaatacc atacaggctt
    17641 ccccatcaca attaccattt tcccaatctt ttttaaatcg ttcatattca tttatataac
    17701 atccagtata ttcatcctgc tctaaaagat aatgtgcttc cattattatt tttctatctt
    17761 cttcattgta attagctaga caatattcat ctccaaattt aactactatt acttttaaat
    17821 catcaatcaa gttatagtat ttcagagtat tttttaatcc tttttctgaa tactcaaagt
    17881 ctacgctttg atttcttacc tgctccaatg ttcttttagt ctttattttc actttataga
    17941 tgttaaacat aatttacaat ctccttctcc agccaatttt tattatttaa tatttaggaa
    18001 attctccata agtcgtagca agacattcaa ttctccactc tggtataacc catgttgtat
    18061 cgttatcacc tacatatgct tttactttat aaagcggggt atttcttttt ctaaatttcg
    18121 tactataaca tttttctaaa atttcacaac caaccattct gttatagtaa cagtttattt
    18181 gatgatatat aatcttttcc cctacagaat atttatattt tagattattt atagattttt
    18241 tatatatgcg atttttcaca taatttgcta atatacaaat aattattagc agtatagtca
    18301 ataaaaaaat cttcataagt tattcctcct aactagttta aatttacatc ctcttattat
    18361 ttacttctcc ttctctagcc aatagtcaca tgagtaccta cttttcctca taaaatgtta
    18421 cattcttaat aactatatct atagacccat tttgattttg tcttactgta tatttcattg
    18481 ggtcctcaaa atcagttaag ttacctttta tttcaaagcc attgtcagtt tttatatttc
    18541 tctttttaag ctttttatca acccattttt tatctatact aaatccttca acaagacctt
    18601 tttcttccat atgttcttta aaactatctt ttaacttatc atctttaatt gttttatcaa
    18661 caaaatcatt tatatcaatt tcatgctttt ctctcaaagt ataatttaat atacttctta
    18721 catcctctgc ttgttttata tcattactaa gagcattagt tatccaattc tcagctgtat
    18781 ttttgaactt cttagtctta tacttatcat cttttatctt agtggcattt aagaactctg
    18841 taacaaactt agaattagct tcttccttct ctgcatcctt gtctaaaacc ctaagatgat
    18901 atttgtcatt cattccactc aatccaacca aagcagcaat tttaaccgtc ttagtctctt
    18961 gtatattaat ttcattttta gacatctgta tattaaattt atcatcttta aactcaattg
    19021 aatgagtata cgaattattg taatcaagct ttaatatagc aactttcttt tcatcttttt
    19081 gagagtataa acaaattgct aagtcgcaag attctaatgt agcattcaat ttcataacat
    19141 caaataaata agctgcaatc tctttagagt tatttaaaaa tgaactttca tcataaataa
    19201 tttgttcaca acacttctta attagattgt tactatagtt attaaatact gctgttctga
    19261 tgtcattatc tcttgatact ttgcttattt tcttttgaaa aaataggacc atatcttgat
    19321 taaccctacc ttcaaaatca ttcaatattg gtgtatcact attcttatct aaaacatgta
    19381 ttataaattt gtgtattatc ataattccac cccttataaa ttttcaaaac gttctataat
    19441 cttctcgctt atagtatttt ttataacttc
//
LOCUS       DAMJVG010000077        19334 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.077, whole genome shotgun sequence.
ACCESSION   DAMJVG010000077 DAMJVG010000000
VERSION     DAMJVG010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19334)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19334)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19334
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.077"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(224..1474)
                     /locus_tag="PC512_002917"
     CDS             complement(224..1474)
                     /locus_tag="PC512_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1015 domain-containing protein"
                     /protein_id="HDF2442649.1"
                     /translation="MATIKPFKAIRPNKYIVDKVAALPYDVMNSKEARRIAEGNPYSF
                     LHIDKSEIDLDENIDLYDEKVYLKARENLDEFRKQEILVKDDKECIYIYKQIMDGRAQ
                     VGIVACISVDESLNGTIKKHEYTRPEKEIDRTKHIKYCDANTGTILVTYKHQRVIDDI
                     INDFMDNNEPLYDFITDDKIEHTVWKIDNDDIIDNLVDKFEKLDYLYIADGHHRTASA
                     ENVAKEMRAKNPNYTGKEEFNYFIAMIAPDENLMVLDYNRVIKDLNGLSEEEFINKIK
                     ENFELEEIEGKEKYKPDKKGTFGMYLGDKWYKMKANKNLLEIEDPVDSLDISILQDYV
                     IDAILGIDNPRVDKRIDFIGGIRGLEELEKRVNEDMKVAFAMYPTSIEDLIRVADANK
                     IMPAKSTWFEPKVRCGLFLHEINE"
     gene            complement(1507..2448)
                     /locus_tag="PC512_002918"
     CDS             complement(1507..2448)
                     /locus_tag="PC512_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HDF2442650.1"
                     /translation="MYNILVTDGIEKEAARKLRELDFNVIEQFYEKDVLGDKLKDVDV
                     LVVRSATKVTKDVIDKALEGKKLKLIVRGGVGLDNIDVKYAQANGIKVMNTPNASSIS
                     VAELTIGQLFVLARFINTANVTMRDGKWEKKKYKGTEINGKTLGLIGFGRIAKEVAKR
                     AELLGMNVIYTDIMGEAQGFNNYKFCDMEEVLENADFLSLHIPFDKNKGAVITEKEIN
                     KMKKGAYLINCARGGLVDEKDLLKALDEGKLSAAAIDVYEQEPTLNLDLVNHPRVSPT
                     PHIGASTVEAQERIGDEIVNVIQDFFLDFNNLIGVAL"
     gene            complement(2688..3764)
                     /locus_tag="PC512_002919"
     CDS             complement(2688..3764)
                     /locus_tag="PC512_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HDF2442651.1"
                     /translation="MSKKLFIPGPIDVKEEVLQKMATPMIGHRGKDASMLQKSISEKM
                     QKLFYTNNTILLSTSSGTGLMEGSIRSCTSKKAAVFSCGSFGDRWYKMAVANNVPADI
                     FKVELGEATTPEMVDKVLSTGEYDLITVTHNETSTGIRNPIEEIGEVVKKYEDVIYCV
                     DTVSSAGGIKVEVDKIGIDICITSVQKALGLPPGMSICTFSQKAIDRAKQVPFRGVYL
                     DLLAMYEYLIKKNYQYPSTPSLSHMFALDFQLDNILDEGLDNRFNRHEDMANLVRNWA
                     KKHFQIFTNENHLSNTLTVIENTQGISVSNLNSKLQERGFQIANGYGDLKEKTFRISH
                     MGDYTVEDVQELLDNIDDILGFNK"
     gene            complement(4137..4652)
                     /locus_tag="PC512_002920"
     CDS             complement(4137..4652)
                     /locus_tag="PC512_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HDF2442652.1"
                     /translation="MDFLAKYKVLKKQNSSKSCLVCGTQNELGLKADFYELENGELVS
                     ICNTKDWHQSYPGRVHGGMSAAILDETIGRAVSINDDQIWGVTVSLELKYKKPVPTDA
                     TIKVVGRITKENRKLFEGTGEIILPNGDIAVTATGKYMKMPIGQIAEGDFSNEEWFFE
                     ESKEKVEYIEL"
     gene            complement(5015..6085)
                     /gene="leuB"
                     /locus_tag="PC512_002921"
     CDS             complement(5015..6085)
                     /gene="leuB"
                     /locus_tag="PC512_002921"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HDF2442653.1"
                     /translation="MNCNIAVIKGDGVGPEIIDEGIKVLNKICCKFNHRFDCEYVLAG
                     GCAIDETGEPLPNKTVETCRKNEAVLLGSVGGPKWDKCKGDKRPESGLLKLRESLGLF
                     ANLRPATMYESIKEASPLRTDIVEKGIDFVVVRELTGGIYFGERGRKIIDGIENAYDV
                     EIYNENEIRRIGKRAFEIARNRNKKLISVDKANVLESSRLWRSIMEDLAKEFEDVELS
                     HMYVDNAAMQVVKDPSQFDVIVTNNIFGDIISDEASMITGSIGMLPSASLREDSFGMY
                     EPIHGSAPDIAGKDIVNPIATILSVSMMLRHSFNLEEEAKCIEDAVQSVLNKGYRTID
                     IYNGVGNVVGTREMGELIVNEI"
     gene            complement(6092..6583)
                     /gene="leuD"
                     /locus_tag="PC512_002922"
     CDS             complement(6092..6583)
                     /gene="leuD"
                     /locus_tag="PC512_002922"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HDF2442654.1"
                     /translation="MIANGSVFKFGDNIDTDVIIPARYLNIADYKELATHCMEDIDDK
                     FISKVKKGDIIVATKNFGCGSSREHAPIVIKESGVSCVIASTFARIFFRNSINIGLPI
                     LECEEAANNIDEGDNIEVDFSTGVIKNITKGKEYKAEPFPEFMQNIILNEGLINSIKA
                     NRG"
     gene            complement(6598..7875)
                     /gene="leuC"
                     /locus_tag="PC512_002923"
     CDS             complement(6598..7875)
                     /gene="leuC"
                     /locus_tag="PC512_002923"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase large subunit"
                     /protein_id="HDF2442655.1"
                     /translation="MGMTMTQKILAKHAKLNEVKKGQLIEADLDVVLGNDITSPVAIR
                     EFEKLGIEDVYDKTKVVMVLDHFTPNKDIKSAEQCKFTRSFAKSKGVVNFFDVGDMGI
                     EHVLLPEKGIVTAGDVIIGADSHTCTYGALGAFSTGVGSTDMGAGMATGKCWFKVPGA
                     IKFVLKNKPNKWISGKDIILHIIGEIGVDGALYKSMEFCGDGVEYLSMDDRFTICNMA
                     IEAGAKNGIFPVDDKTMEYINSHKCSTMTKDVNIYEADEDAVYDEVYEIDLAELKETV
                     AFPHLPENTRTVDEIDKDIKIDQVVIGSCTNGRISDLEVVAEIMKGKKVADGVRVMIF
                     PGTQKVYLEAIEKGYITTFIEAGAAVSTPTCGPCLGGHMGILAAGEKSISTTNRNFVG
                     RMGHVDSEVYLASPAVAAASAITGKISKPSEII"
     gene            complement(7832..9574)
                     /gene="leuA"
                     /locus_tag="PC512_002924"
     CDS             complement(7832..9574)
                     /gene="leuA"
                     /locus_tag="PC512_002924"
                     /EC_number="2.3.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HDF2442656.1"
                     /translation="MKCGKYKKYDKMQIVNRKWPDNEIFKAPIWCSVDLRDGNQSLPT
                     PMSVNEKVRMFKMLIDTGFKEIEVGFPSASNTEYTFLRKLIDENMIPDDVTIQVLTQS
                     RAHLIEKTFESIRGCKKAIIHLYNSTSVLQRDVVFNMSKQEIIDIAVEGAKLFNEEVK
                     KYPETEFTFEYSPESFTGTEMDYALEICEAVIDVWKPTPQKKVIINLPSTVEMATPNV
                     YADQIEWFCKNISCRDSIILSLHTHNDRGTCTAASELGLLAGADRLEGTLFGNGERTG
                     NMDIVNVGLNLYTQGIDPELDFSNIDKIIGIYEDCTKLMVHDRHPYAGNLVHCAFSGS
                     HQDAIRKGMIAMKNRDNDYWEVPYLPIDPHDIGREYKEIIRINSQSGKGGAVYIMETD
                     YGFMIPKNMHSDFGNVVKMESDRIGEELSSEAIFNLFKKEYIEVESPYKVKKYKIKSM
                     DELNYENDDSNDTNMIEMTARISYMGNEQRIVGIGNGPVDSFNNALKQCGMKDYKFRY
                     YWEHALEEGSHSRGVAYVGIEHNNEVYFGVSISENINTAAINALMNAINKSYIEEEIK
                     NGDDYDAENISQTC"
     misc_binding    complement(9698..9944)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(10092..10538)
                     /locus_tag="PC512_002925"
     CDS             complement(10092..10538)
                     /locus_tag="PC512_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442657.1"
                     /translation="MSKNKFIYMNYYDNGYFKKGMTIYMVLALIILATIFIYSTTILY
                     ILCIITAVFLFKQGRDFSNKYEGKVYITLDNHSILINNQCIFSIKSKQSQKFNYKIIE
                     KIEVVKNILNIYTNESNYKIRLRALSLEDEKKLLNIIDEKMKKFKA"
     gene            complement(10559..11278)
                     /locus_tag="PC512_002926"
     CDS             complement(10559..11278)
                     /locus_tag="PC512_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase"
                     /protein_id="HDF2442658.1"
                     /translation="MKKSIMDVHCHTLISGHAHSTFKENVEEASKKNIKYLGISDHGP
                     NMPGGPHPFYFYNLHLLPREVQGVKILRGIEGNIMDYNGNLDVQEDMLQHLDYIIASL
                     HRPCIASGTKEENTNAILKVMDKPKVKIIGHPDDSRYPLDYEPIVKKAKDKNILLEIN
                     NSSLSSNSHRTGTWENVSHMLTLCKTYGARVILGTDSHICYSIGEFENAEKVLEAVDF
                     PDELVINYHEDEIIEFFDINF"
     gene            complement(11396..12670)
                     /locus_tag="PC512_002927"
     CDS             complement(11396..12670)
                     /locus_tag="PC512_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HDF2442659.1"
                     /translation="MFIMENDLTMQELLDQQEQVFSKVKVGELTTGKITAVRNDEVQL
                     GLDYGFDGIIPISELNIEKNQYIEDIYHIGDEITAVITKVSQKDGTITLSKLQLDKRN
                     DFAELQKAYDEHRIITVNVEKNIDKGVFANYNTYTFFIPISQLDTKFITDTSKFVGLN
                     LEVYIKELDVRKNRLVASHRDVLQERINKEREERRAQIKAEKEAERARIKQEREEEKA
                     RIKAAKEDLFNSLEVGQKRDGKVTKIMPYGAFVDIGGIEGLAHINNLAWTRVESVEDV
                     VSEGQEVEVYVLDVNKETKKIALALKDINNDPWDLIAKEVQIDDVVNAKVLRIIEKGA
                     FVQIKEGVDAYLPISELSDTRVAKVTNVVNIGDEVKVKILDFKPKTKRMLVSIKEATR
                     EPEEDITEYLEVEESLGSIGELFKDKFKDLEV"
     gene            complement(12870..14237)
                     /locus_tag="PC512_002928"
     CDS             complement(12870..14237)
                     /locus_tag="PC512_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2442660.1"
                     /translation="MENSNTNLGSESVGKLLFKLATPAIIAQIVNVLYNIVDRIFIGR
                     MENGEVAMAGVGVAFPIIIIITACSYLIGMGGGPLAAIKMGEQNNDEAEKIMSNSFSV
                     LVILAILLTIGFKIGKEPLLWMFGASESTIGYSMDYLNIYLIGTVFVQISMGMNTFIN
                     TQGFATTGMMTVAIGALINIILDPIFIFGFNMGVKGAALATIIAQGVSAIWVLMFLFG
                     KKSILKIKKKYMIPKASIILPVLGLGISPFIMQSTESLVLIALNSKLQMYGGDLAVGS
                     MAIMSSIMQILMLPNMGVTQGAQPIISYNYGSGQLDRVKKTFKLCLLSCFTYSTILWL
                     LLMIFPAFFVSIFNKNPQLLSMTSWSIKIYFAGAFMFGIQIACQQTFLALGKATISLV
                     LALLRKIVLLIPLIFILPTFFNEKLFAVILAEPVADITAATITAISFFIFYKCFLSKP
                     KAIKE"
     gene            complement(14487..14951)
                     /locus_tag="PC512_002929"
     CDS             complement(14487..14951)
                     /locus_tag="PC512_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small multi-drug export protein"
                     /protein_id="HDF2442661.1"
                     /translation="MSLRIGGNSLGYLHILILSMVPVTELRGAIPIGIAMGLNPIWVY
                     VFSVIGSTLVSIPLILTFRHVLQFLRGKKLFKGIADVIDRKINSRMKKLKSVSIIGII
                     LFVGIPLPTTGTWTASAIASILKMRIKDAFMGVFLGNLLSGVIVSALSLHII"
     gene            complement(14956..15585)
                     /locus_tag="PC512_002930"
     CDS             complement(14956..15585)
                     /locus_tag="PC512_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family hydrolase"
                     /protein_id="HDF2442662.1"
                     /translation="MKKSVLLLDVDYTVINTDSMIDFFIYSLKNKTFKTIIKLPYIIF
                     ILFMYLIRIIPLKKAKEAIFYPIVDFSEEDLKKFFDDCIMKKINESMKKVIYKNKEED
                     NVIIMITASPYAYMKYFKYYGLADEVIGTEFFYENSRYKNKFIGENCKGIEKVKRIKA
                     VLGKLGIEIDYENSYAYSDSKSDLPMLSLTKNAFLVSKKDGEVIEQINS"
     gene            complement(15619..16506)
                     /locus_tag="PC512_002931"
     CDS             complement(15619..16506)
                     /locus_tag="PC512_002931"
                     /EC_number="2.4.2.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decaprenyl-phosphate phosphoribosyltransferase"
                     /protein_id="HDF2442663.1"
                     /translation="MKQTNTSIRLLTKISDYIKLMRIKQYIKNFFVFSAIIFSNNILN
                     INLFLNTFIAFVCFCLMSSSVYALNDAIDMDKDKKHPKKCNRPVASGRISKKSANILF
                     VVLALISVCLSTVVSFNLSIILSLYLINNILYSLKLKNIILLDVFSISLGFILRVYAG
                     CVAISVSLSNWIILCTFFLSLYLALGKRKKEIETLRDDAVEHRKILEDYDIENLNQMM
                     IVILSSTIVCYALYSTSNPEKPHMIFTTIFVVYGVLRYNYIINTTNENNPTDIVLKDN
                     ALKINVILWIITCLIILIF"
     gene            complement(16535..17773)
                     /locus_tag="PC512_002932"
     CDS             complement(16535..17773)
                     /locus_tag="PC512_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442664.1"
                     /translation="MDGDILMSKILKYKNEMFLFILVVITYLIITKIFFSKTTIFYDL
                     NNTYDVLLDTDTGVLFNLNVFAISQDNSKHILFSAIISIFAYPIYLFCTSIANPGTTD
                     FNSAYGFGLICLQIITSAMSITLVFNHIKKIKMQRLTLILLTMIMIFSFPQLFMTLNV
                     ERFIYSQFSLIFFIVIANKMKGKNSYLVELAAIPLFGITISNIYLYFFNMIFEFKLKI
                     GKMLKHLITFILMAYICVVSTKSYESFMNLGNVIQYDTKFISGEPILEKIAMIIERLL
                     YSVFYFPGASIKKGLFLQNGEVATIPVILTLLALCFCVLSVIENSEKRVPKLCMGIII
                     FNLTLHGIVGYNLVNSSIMAINFSFAVIILLAYFTKALRKNEKNMYNIFLSLLLVTIV
                     ISNVNGFIEILNIGIKSYPV"
     gene            complement(18157..19299)
                     /locus_tag="PC512_002933"
     CDS             complement(18157..19299)
                     /locus_tag="PC512_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HDF2442665.1"
                     /translation="MRYVEYGKTGKMVSVVGYGGLRFDLEKSNQENADLVKYAYEKGI
                     NYFDTAPGYCDDRSEDIFGLAFRQMIKEGKTDFYVSTKEKPKACDTSEKAIEAVKKSI
                     ERLGVSKINFYHVWNIRKMEHYELAMRPGGQYEGLLKCKEEGLIDHIVFSSHQPGDEV
                     IDILSENKFEGVTMGINILNFPYRLKGAKYAVDNGYGVVAMNPLSGGTIPKYNKELSF
                     LSKDGESTIESALRFNIGISQISISLIGFNKKQDIDDACKIADENRIYSDEDIHDIET
                     RLNKNMNEICTGCGYCKVCPKGINTPAYMLFYNEKQMFKKSDEEMTKLVYGLGHWNYT
                     MNSKAKAKECISCGKCEVECTQHLPIIDRLKEIKKWEEDGANSVKV"
BASE COUNT         6214 a         3543 c         1974 g         7603 t
ORIGIN      
        1 tacacattta aaaccttata aatatacaaa tacaattata tgaattttca tcctcaatta
       61 tagcatagaa tatgactatc tatatcctaa aattatccat ttctaaaaaa aaggtaacta
      121 ttattaagaa tatcaactta tagaatttat attccacata cgattttcaa tcaaaaaaac
      181 aagggctaaa aagtgaattg tgcacttttt agccctttat taattattca tttatttcat
      241 gtaagaatag accacatctt actttaggtt caaaccatgt tgacttagct ggcattatct
      301 tatttgcatc tgctactctt attaaatctt caatactagt aggatacatt gcaaatgcta
      361 ctttcatatc ttcattaact cttttttcta attcttcaag acctctaatt ccaccgataa
      421 aatcaattct tttatctact ctaggattat caattcctaa aatagcatca ataacatagt
      481 cttgtaatat agaaatgtct aatgagtcaa cagggtcttc tatttctaat aaatttttat
      541 ttgctttcat tttataccac ttatcaccta ggtacattcc gaaagttcct tttttgtcag
      601 gtttatattt ttcttttcct tctatttctt ctagttcaaa attttctttt attttattta
      661 taaattcttc ctcgcttaaa ccatttaagt ctttgataac cctattataa tccaaaacca
      721 ttaaattctc atctggtgca atcattgcta tgaagtaatt aaattcttct tttccagtat
      781 aatttggatt tttagctctc atttctttgg ctacattttc tgctgaagct gtcctatgat
      841 gaccatctgc aatgtataga taatctaatt tttcaaattt atctactagg ttatctatta
      901 tatcatcatt atcaatcttc catactgtat gctctatctt gtcatctgtt atgaaatcat
      961 ataaaggttc attattatcc ataaaatcat tgattatatc atctatcacc ctttgatgtt
     1021 tgtaagttac aagtatagtt cccgtattag catcacagta ttttatgtgt ttagttctat
     1081 caatttcctt ttctggtcga gtgtactcat gtttttttat tgttccattc aagctttcat
     1141 caactgatat acatgctact ataccaactt gagctctacc atccatgatt tgtttatata
     1201 tatatataca ctctttgtca tcttttacta gaatttcttg ttttcgaaac tcatctaaat
     1261 tttctcgcgc ttttaaataa actttttcat catataaatc tatattttca tctaaatcaa
     1321 tttctgattt atctatatgc aaaaatgaat atggattccc ttctgcaatt cttctagctt
     1381 ctttactatt cataacatcg taaggaagtg ctgctacttt atctactata tatttatttg
     1441 gtctaatcgc cttaaatggt ttaatcgttg ccattactaa tttcctccct aattatacaa
     1501 aatattttat aatgctaccc ctattagatt gttgaagtca agaaagaaat cttgaatcac
     1561 atttactatt tcgtctccta ttctttcttg agcttctact gtagatgccc caatatgagg
     1621 tgtaggagaa actcttggat gatttactaa gtctaaattt aatgtaggtt cttgttcata
     1681 aacatctata gcagctgctg ataatttacc ttcatctaat gcttttagta aatctttttc
     1741 atcaactaaa ccgcctcttg cacagtttat taaataagcc cctttcttca tcttatttat
     1801 ttctttttca gttattactg cccccttatt cttatcaaat ggtatgtgta aagataagaa
     1861 atctgcattt tctaaaactt cttccatatc acagaattta taattgttaa agccttgcgc
     1921 ctcacccatt atgtcagtat atataacatt catacctaat aattctgctc tctttgcaac
     1981 ttcttttgca attcttccaa aacctataag tccaagtgtc tttccattaa tttctgtacc
     2041 tttatacttt ttcttctccc attttccatc tctcatagtt acatttgcag tatttatgaa
     2101 tcttgcaaga acaaataatt gacctattgt aagctctgca acagatatac tgcttgcatt
     2161 tggagtattc ataactttta tgccattagc ttgagcatat ttaacatcta tattatccag
     2221 acctactcca cctcttacta tcaacttcaa ctttttaccc tctaatgctt tatctattac
     2281 atctttagta actttagtag ctgaacgtac tacaagtaca tcaacatctt taagtttatc
     2341 tcctaaaaca tctttttcat aaaactgctc tatcacatta aaatctaact ctctcaattt
     2401 tctcgctgct tctttctcta ttccatcagt aactaatata ttatacataa caaactcctc
     2461 caatttttat tcacttaatt tttccaattt ttatttttta aagtattttc atcaataaaa
     2521 aactttactt aatttaactt tctgtttata taattttcaa aatatttttt tattaaagtc
     2581 atatcaaatt ttcctattgt ttgttaaaaa tttaatatgt aatttttata aaatattatt
     2641 tattatatat tctaaattta tcttaaaaca tacatatttt tacaatatta tttattaaaa
     2701 cctaatatat catcaatatt atctaataat tcttgtacat cttcgacagt atagtcaccc
     2761 atatgtgaaa ttctaaaagt tttttctttt aaatctccat agccatttgc tatttggaat
     2821 cctcgttctt gtaattttga atttaaattt gatacactaa taccttgagt attttctata
     2881 acagtaagtg tattggataa gtgattttca ttggtaaaaa tttggaagtg ttttttagcc
     2941 cagtttctaa ctaagtttgc catgtcttca tgtctgttga atctgttatc taggccttca
     3001 tctaatatat tatctaattg gaaatctaaa gcgaacatgt gagaaagaga tggtgttgaa
     3061 gggtattggt agtttttctt gattaagtat tcatacattg ctaacaaatc aagatatact
     3121 cctctaaaag gtacttgctt agctctatcg attgcttttt gagaaaatgt gcaaatagac
     3181 attcctggtg gtaatcccag tgctttttgt actgatgtta tacaaatatc tattccaatc
     3241 ttatcaacct cgacttttat tccaccggct gaacttacag tatctacaca gtagattaca
     3301 tcttcatact ttttaacaac ttctccaatt tcttctattg gatttcttat tccagttgaa
     3361 gtttcattgt gagttacagt tattaaatcg tattctccgg tagaaagcac cttatcaacc
     3421 atttctggcg ttgttgcctc tcctaattca actttaaata tatccgctgg gacattatta
     3481 gccactgcca ttttgtacca tctatcacca aaggatccac aggaaaatac tgctgccttt
     3541 ttggatgtac aggaacgaat ggagccttcc attaaaccag ttccggatga cgtggataaa
     3601 agtatcgtgt tgtttgtata gaatagtttt tgcatctttt cacttatact cttttggagc
     3661 atagatgcat cttttcctct atgtcctatc attggtgtag ccatcttttg caagacttct
     3721 tctttaacat caataggacc aggaataaat aatttcttac tcattataat tccccccttt
     3781 ttagtttgta atatggatag cgtttttact gtccttattt ttaataacta taatatcaag
     3841 ctgaattaac tatgtcaaca taaaatttat tttttatata taatttattt tatatatttt
     3901 atgaaaacat tcattttcta ccttttcata agtctgaatt ttctgaatta ttctctcaaa
     3961 aaaaatatac tttttatcta tataaattaa tttttttagt atgtaaattt gacgctatta
     4021 cgataaatct ttttagtata actaatttat ttttatcttg tatttttatt gtatttttga
     4081 attttatttt ttctaaatat aaaatttatg ttttaaaatg taaaattttt atttaatcaa
     4141 agttcaatat attccacttt ttctttcgat tcttcaaaaa accattcttc attagaaaaa
     4201 tcaccttctg caatttgtcc aataggcatt ttcatatact ttccagttgc tgtcactgct
     4261 atatctccat ttggtagaat tatttctcct gtaccttcaa ataattttct gttttcttta
     4321 gttattcttc caacaacttt tatagtagca tctgttggta ctggtttctt atatttcaac
     4381 tctaaagata ctgttactcc ccatatttgg tcatcattta tacttacagc tcttccaata
     4441 gtctcatcca atattgcagc agacatacct ccatgaactc tcccaggata actttgatgc
     4501 caatcctttg tattacaaat tgatacaagc tctccatttt caagttcata aaaatctgct
     4561 ttaagtccta gctcattttg tgttccacaa actaaacaag atttactact attttgcttc
     4621 ttcaaaactt tatactttgc caaaaaatcc atctcctaac cgacattagt agtcgcttaa
     4681 tattaaataa ttctaaaata tattatataa tattaataaa atccctgcaa acttctaata
     4741 ataaaaatag gctacttcaa tatgataagt ttaatttaaa gtattatttt ccaaaaaata
     4801 actttatcaa aatagaaact caaagtagat ataaacctct ttttcgttat taaaatagta
     4861 aaaatatatt tgacttaata taaaaaagag tgtctcatta actaataaag tttattttga
     4921 gacacccctc ataaaacaaa ttatactaca atagattttt actaattcta caagttatat
     4981 atttaaatta tattattcaa attaaactat aattctaaat ttcatttact attaattcgc
     5041 ccatttccct tgttcctaca acatttccca caccattata gatatcaata gttctataac
     5101 ctttattgag tacactttgt acagcatctt caatacactt agcttcttct tctaagttaa
     5161 aactatgtct taacatcatg cttacagata gaatagtcgc aattggattt acaatatctt
     5221 ttccagctat atcaggtgca cttccatgta ttggttcata cataccaaaa ctatcttctc
     5281 taagtgatgc tgatggtaac atacctatag aacccgtaat catagatgct tcatcagata
     5341 ttatatctcc aaatatatta ttagtcacta ttacatcaaa ttggctaggg tcttttacaa
     5401 cttgcatagc agcattatca acatacatat gtgacagttc tacatcttca aactctttag
     5461 ctaagtcttc cattatactt ctccaaagtc ttgaactctc aagcacattt gccttatcta
     5521 cacttataag ttttttattt ctatttctgg ctatttcaaa agctctctta ccaattcttc
     5581 ttatttcatt ttcgttatat atttctacat cataagcatt ttcgatacca tcaatgattt
     5641 ttcttccacg ttctccaaaa taaatgcccc ctgttaattc ccttacaaca acaaaatcaa
     5701 tgcctttctc aactatatcc gttctaagtg gtgaagcttc ttttatactt tcatacattg
     5761 tagctggtct taaatttgca aataaaccca atgactctct taattttaaa agaccagact
     5821 ctggtctttt atctccctta catttatccc actttggtcc tccaacagaa ccaagcaata
     5881 cagcttcgtt ttttcgacaa gtttcaacag ttttattagg tagaggttct ccagtttcat
     5941 caatcgcgca tcctccagct aatacatatt cacaatcgaa tctatgatta aatttacaac
     6001 aaattttatt tagaaccttt ataccttcat ctataatttc cggtccaaca ccatcacctt
     6061 ttatgactgc tatattacaa ttcatactcc actaccccct atttgctttt attgagttaa
     6121 ttaagccttc atttaatata atattttgca taaactcagg aaatggttct gctttatatt
     6181 cttttccttt tgttatattt tttatcacac ctgtagaaaa atctacttct atattatccc
     6241 cttcatctat gttattggca gcttcttcac attcaagtat aggaagccct atatttatag
     6301 agtttctaaa aaatattcta gcaaaagtag aagcaatcac acaggatact ccactttctt
     6361 ttattacaat tggtgcatgt tctcttgatg aaccacaacc aaagttttta gttgcaacta
     6421 taatatctcc tttttttacc ttagaaataa atttatcatc aatatcctcc atacaatgcg
     6481 ttgctagttc tttataatca gctatattta aatatctagc tggtattatt acatctgtat
     6541 ctatattgtc accgaattta aaaacacttc cattggcaat cataaatttt acctccctta
     6601 aattatttct gatggttttg atatttttcc agttatagct gatgctgctg ctacagctgg
     6661 gcttgcaaga tacacctctg aatcaacatg ccccattctt cctacgaaat tcctatttgt
     6721 tgttgaaatg gatttttctc ctgctgcaag tatacccata tgtcccccta gacatggacc
     6781 acaagttggt gtagaaactg ctgctcctgc ctctataaaa gtggtaatat accctttttc
     6841 tatagcttca agatatactt tttgagttcc aggaaatatc ataactctaa ctccatctgc
     6901 tacttttttg cctttcatta tctcagctac tacttcaagg tctgatattc ttccatttgt
     6961 acaagagcct attacaactt ggtctatctt tatatcctta tctatctcat ctactgttct
     7021 agtattttca ggaagatgag gaaaggctac tgtttctttt agttcagcta aatctatttc
     7081 gtatacttca tcatagactg catcttcatc tgcttcatat atatttacat cttttgtcat
     7141 agttgaacac ttatgtgaat ttatatattc catagtctta tcgtctactg gaaaaattcc
     7201 attttttgct cctgcttcta ttgccatatt acaaatagta aatctatcat ccatagataa
     7261 gtattctact ccatctccac aaaattccat tgacttgtaa agtgctccat caacacctat
     7321 ctcccctatt atatgaagta ttatatcttt accacttatc catttatttg gtttattctt
     7381 caaaacaaat tttattgctc caggaacctt aaaccaacat tttcctgtag ccatacctgc
     7441 tcccatatca gttgaaccta caccagtaga aaatgctcct aatgctccat atgtgcaagt
     7501 atgagagtca gcacctataa ttacatctcc agcagttact ataccttttt caggaagaag
     7561 aacatgctct attcccatat ctcctacatc aaaaaaattt acaactcctt ttgattttgc
     7621 gaaacttctt gtaaatttac attgttctgc actctttata tctttattag gtgtaaagtg
     7681 gtctaaaacc atcactactt tagtcttatc ataaacatct tcaattccta atttttcaaa
     7741 ttctctaatg gctactggtg atgttatatc attacctaaa actacatcta aatctgcttc
     7801 gattaattgc cctttcttaa cttcatttaa tttagcatgt ttggctaata ttttctgcgt
     7861 catagtcatc cccatttttt atttcctcct caatataact tttatttatt gcattcataa
     7921 gtgcattaat agctgctgta tttatgtttt ccgatatact tacaccaaaa tagacttcat
     7981 tattgtgctc tattcctaca taagctaccc ctcttgaatg tgacccttcc tctaatgcat
     8041 gttcccagta atatctaaat ttataatctt tcatgccaca ttgctttagt gcattattaa
     8101 atgaatctac aggtccattt cctataccaa caatcctttg ttcatttccc atataactta
     8161 ttcttgcagt catctcaatc atattagtat cattagaatc atcattttca tagtttaatt
     8221 catccattga ttttatttta tacttcttaa ctttataagg gctctcaact tcaatatatt
     8281 ctttcttaaa caaattaaat attgcttcac tactaagttc ttccccaatt ctatcagatt
     8341 ccattttgac tacatttcca aaatcagaat gcatattttt aggtatcata aatccataat
     8401 ctgtttccat tatataaaca gctcctcctt ttccagattg gctatttatc cttataattt
     8461 ctttgtattc tcttccaata tcatgagggt ctattggtaa atatggaact tcccagtaat
     8521 cattatctct gtttttcatt gctatcatgc cttttctaat agcatcttga tgtgaacctg
     8581 aaaaagcaca atgtacaaga ttacctgcat atggatgtct atcatgtacc ataagttttg
     8641 tacagtcttc atatatacct attatcttat ctatattgct aaaatctagc tctgggtcta
     8701 ttccttgtgt ataaagatta agtcccacat ttactatatc catattccca gttctttcac
     8761 catttccaaa tagtgttcct tcaagtctat cggcaccagc caataatcca agttcacttg
     8821 cagccgtaca agttcctcta tcattgtgag tatgcaaact tagtataata gaatccctac
     8881 aacttatatt tttacaaaac cattctattt ggtctgcata tacgtttggt gttgccattt
     8941 caactgttga tggaagattt attattactt ttttttgagg agttggtttc caaacatcta
     9001 tcactgcctc acatatttca agtgcataat ccatctctgt tcctgtaaaa ctctctggtg
     9061 aatattcaaa agtaaattct gtttctggat atttttttac ttcttcatta aataattttg
     9121 ctccttcaac tgctatatct attatttctt gtttactcat attaaaaacc acatctcttt
     9181 gaagaacaga tgtagagtta tataaatgta taattgcttt tttacatccc cttattgatt
     9241 caaatgtttt ttctataaga tgagccctag attgtgtaag tacttgtata gttacatcat
     9301 ctggaatcat attctcatct attaattttc ttaaaaatgt atactctgta tttgatgctg
     9361 atggaaatcc tacctctatt tctttaaatc ctgtatcaat aagcattttg aacattctga
     9421 ctttttcatt tacactcata ggtgttggca gtgactgatt tccgtctctt aaatcgacac
     9481 tacaccaaat tggagcctta aatatttcat tatctggcca tttacgattt actatttgca
     9541 ttttatcata ttttttatac tttccacact tcatgttatt tccccctttt tctgtttttt
     9601 gtattcagta tacctcatat cgacgcaatc ctgcacaatt cataaggata aatgtcaatt
     9661 ttatcattag aataaaaaaa acctcatctc taataaaatt agagacgagg ttttgctcgc
     9721 ggtaccactc tatttagctt tctaaaaagc tcccttagta atagccaata caataattat
     9781 aatgactata tttcctataa cgtggaatta ctccgattat tctaagattt aaatcttaga
     9841 aaacagctcc tagacaagtt cagaactatc aactactaaa tcacaccatc ctttagctct
     9901 ctgaaagttt cattgttctt actacttcta ttcatcactt ttttaatcat ttaaattttc
     9961 taaatatttt gatttaatag ttattatata cacattaaaa tgtattgtca acacaaaaaa
    10021 taattatctc aattttttat ttttgataag caattctata aaacatgcta actattgaaa
    10081 acagtatgat attatgcctt aaactttttc atcttttcat ctatgatatt caataatttt
    10141 ttttcatctt ccaaactcaa tgcccttaat ctaattttat aattagattc gttagtgtat
    10201 atatttaata tattttttac tacttctatt ttttctatta tcttataatt aaacttttga
    10261 ctttgtttag attttatact gaatatacat tgattattta ttaatattga atgattatcg
    10321 agagtaatat atacttttcc ctcatattta tttgaaaaat cacgaccttg tttaaataga
    10381 aaaactgctg ttattataca taaaatatat aatattgtcg ttgaatatat aaaaattgta
    10441 gctaaaatta taagtgctaa aaccatatat atagtcattc cttttttaaa ataaccattg
    10501 tcataataat tcatatagat aaacttattt ttactcaaat tttttcactc ccaagattct
    10561 aaaaatttat atcaaaaaat tctataattt catcttcatg ataatttatg actaattcat
    10621 ctggaaaatc tactgcttct aaaacttttt ctgcattttc aaattctcct atagaataac
    10681 atatatgaga gtcagtacca agaattactc ttgcaccata tgttttacac aatgtcaaca
    10741 tatgacttac attttcccaa gtacccgttc tatgagagtt tgaacttaat gatgaattat
    10801 ttatttctaa aaggatattt ttatctttag ctttttttac tataggttca taatctaaag
    10861 gatacctact gtcatctgga tgtccaatta tttttacctt aggtttatcc ataactttta
    10921 aaatagcatt tgtattttct tcttttgtac cagaagctat acaaggtcta tgcaaacttg
    10981 cgattatata atccaaatgt tgcaacatat cttcttgaac atctaaatta ccattataat
    11041 ccattatatt tccttctatt cctctaagaa tctttacgcc ttgcacttca cgtggaagca
    11101 aatgcaaatt ataaaaatag aatggatgtg gtcctcctgg catattaggt ccatggtctg
    11161 atattcctaa gtattttata ttcttcttac tcgcctcttc gacattttcc ttgaaagtac
    11221 tatgtgcatg tccacttatt agagtgtgac aatgtacatc cataatagac tttttcatta
    11281 aatttcctcc taatatttta cataaattcg tgaaaatagc taaagggcta tttcaaaact
    11341 aaagctgtca taatagacag tgtaacgttt taaaacagcc ccattttcaa ttattttaca
    11401 cttctaaatc tttaaattta tctttaaata attctccaat acttcctaaa gattcctcta
    11461 cttctaggta ttctgttata tcctcttctg gctctctagt tgcttctttt attgaaacca
    11521 acattctctt agtctttggt ttaaaatcaa gaatcttaac tttaacctca tctccaatat
    11581 taacaacatt agtaacttta gccactctag tatcactcaa ttcagatatt ggtaaatacg
    11641 catctacacc ttctttaatt tgaacaaaag cccctttttc tattattcta agaactttag
    11701 cattgacaac atcatcaatt tgtacttctt ttgctattaa atcccaaggg tcattattta
    11761 tgtcttttaa tgccaaggca atttttttag tctctttatt tacatccaac acataaactt
    11821 ctacttcttg tccctctgaa acaacatctt caacactttc aactcttgtc caagctaaat
    11881 tatttatatg tgctaatcct tcaatcccac caatatccac aaatgcacca taaggcatta
    11941 tctttgtcac cttaccatct cttttttgtc caacttcaag agaattaaat aagtcttctt
    12001 tagctgcttt gatacgagct ttttcttctt ctctttcttg cttaattctt gctctttcag
    12061 cttctttttc tgccttaatt tgagctcttc tttcttctct ctctttattt atacgctctt
    12121 gtaatacatc tctatgagat gctacaagtc tattttttct aacatccaat tcttttatat
    12181 aaacttctaa gttaagacca acaaatttag atgtatctgt aataaatttt gtatcaagtt
    12241 gagaaattgg tataaaaaat gtatatgtat tgtaattagc aaatacacct ttatctatat
    12301 tcttttcaac atttacagtt attattctat gttcatcata agccttttgt aactcggcaa
    12361 aatcatttct tttgtcaagt tgtaatttag ataaagttat tgtaccatct ttttgagata
    12421 cttttgttat tacagcagtt atttcatcac ctatgtggta tatatcttct atatattgat
    12481 ttttttctat gttcaattca cttataggta ttattccatc aaacccatag tctaatccta
    12541 attgtacttc atcatttctc actgcagtta tttttccagt tgtcaattct ccaactttca
    12601 ctttgctgaa tacttgttct tgctggtcaa gtaattcttg cattgttaaa tcattttcca
    12661 ttataaacat cctttcctct tattgattat catatctgta aatattatac cattaatatt
    12721 gcaaatactt acatttttct tactataatt tttaaaataa attcaacttc atatatttat
    12781 acattataga aaatatctta ttaaattaaa atacaaattc taatttttat ctaataaaat
    12841 attttcataa aaaatttata ttgtatatct tattctttta ttgctttagg ttttgataga
    12901 aaacatttat aaaatataaa gaaagaaatt gctgttatag tagcagctgt tatatctgca
    12961 actggctctg ctaaaattac tgcaaaaagt ttttcattaa agaatgttgg aagtataaat
    13021 attaaaggta ttaaaagtac aatctttcta agtagagcta aaaccaaaga tattgttgct
    13081 tttccaagtg ctaaaaatgt ctgttgacaa gctatttgaa tcccaaacat aaaagcacca
    13141 gcaaaatata tttttatact ccaactagtc atactaagta actgcggatt cttattaaat
    13201 atactaacaa aaaatgcagg aaatatcatt aataaaagcc ataaaatagt agaatatgta
    13261 aaacatgaca acaaacacaa cttaaatgtc ttttttactc tatcaagttg acctgaacca
    13321 taattataac ttattattgg ttgtgctcct tgtgtaaccc ccatattagg aagcataaga
    13381 atttgcatta tactgctcat tatagccatt gaacctactg ctaaatctcc tccatacatt
    13441 tgtaatttac tatttaaggc tataagtact aaactttctg tagattgcat tataaatgga
    13501 gagattccca aaccaagcac tggtaagatg atacttgctt ttggtatcat atacttcttt
    13561 tttattttaa gtatactttt ctttccaaag agaaacataa gtacccaaat agcagaaacg
    13621 ccttgtgcaa ttatagtagc taatgcagct ccttttacac ccatattaaa gccaaatata
    13681 aaaatcgggt caagtattat gtttattaaa gcacctatag caactgtcat cattccagtt
    13741 gtagcaaacc cttgggtatt tataaaagta ttcataccca ttgaaatctg aacaaacact
    13801 gtacctatta aataaatatt taaatagtcc attgaatatc caattgtaga ttcacttgct
    13861 ccaaacatcc aaagtaaagg ctcttttcca atcttaaaac ctatagtcaa aagtattgct
    13921 aaaatcacca gtacagaaaa actgttactc attattttct ctgcctcatc attgttttgc
    13981 tcacccattt ttatagcagc taatggacct cctcccatac cgattaaata actacatgca
    14041 gttattataa ttattattgg aaatgccact ccaacaccag ccatagcaac ttctccattt
    14101 tccattctac caataaaaat cctatcgact atgttgtata aaacatttac aatttgtgcg
    14161 ataatagcag gtgtagcaag tttaaataat aatttaccca cactttcact acctaagtta
    14221 gtgtttgaat tttccatttt aaaacctcct caatccaata attaaaatgt atcactaaaa
    14281 ttttattcta tataaaaatt tcattttatt agcagacaaa tttagagtac tttccctaca
    14341 agtaatacta tactatattt cttttgccat agtaaacatt ttagaactaa ctgaagttaa
    14401 atactttatc tcatttttta tttattatta aaaatttttc acacatactc ataaaaaaac
    14461 tatccaagta tattacttag atagttttat attatatgta aagaaagagc tgaaactata
    14521 acccctgata acaaattgcc aagaaatact cccataaaag catcttttat tctcattttt
    14581 aatatggaag ctatagcaga tgcagtccac gttcctgtag ttggcagtgg tatacctaca
    14641 aatagtatta taccaattat cgaaacactt tttaatttct tcattcttga gtttattttt
    14701 ctatcaatta catcagcaat ccctttaaat agtttcttcc ctcttaaaaa ttgtaataca
    14761 tgtctgaatg tcaatatcaa gggaatcgat accaatgtag aacctattac actaaataca
    14821 taaacccata taggatttaa gcccattgca atacctatag gaatggctcc cctcaattct
    14881 gttacaggaa ccatagataa aattaatatg tgtaaatatc ccaaactatt ccctcctatt
    14941 ctaagtgaca ttaagttatg aatttatttg ctctataacc tcaccatcct ttttactaac
    15001 taaaaatgca tttttagtca atgaaagcat tggtaaatca ctcttagagt ctgaatatgc
    15061 atatgaattt tcataatcaa tctctatccc aagtttacct aatacagcct ttattctttt
    15121 tactttttca attcccttac agttttctcc aatgaattta tttttatatc ttgaattttc
    15181 ataaaaaaac tccgtgccta taacctcgtc tgcaagacca taatacttaa aatatttcat
    15241 atatgcatat ggagatgcag ttatcataat tataacatta tcttcttctt tatttttgta
    15301 aataaccttt ttcatagatt cgttaatttt tttcattatg caatcatcaa aaaacttttt
    15361 taaatcttct tcactaaaat ctactattgg ataaaagatt gcctcttttg ccttcttcaa
    15421 tggtattatt ctaattaaat acataaatag aataaaaata atgtatggta actttataat
    15481 agttttaaag gttttatttt ttaaagagta aataaaaaaa tctatcatgc tatcagtatt
    15541 tataacagta taatctacat caagtaataa tacacttttt ttcataagta tttccccatc
    15601 ctatcactaa aaatatcact aaaaaatcaa tattattaaa catgtaatta tccataagat
    15661 tacgtttatt tttaaagcat tatcttttaa gacaatatca gtaggattat tttcatttgt
    15721 agtgttaatt atataattat atctaagtac accataaact acaaatattg ttgtaaatat
    15781 catatgtggc ttttctggat tacttgtaga atacaatgca taacatacaa ttgtagaact
    15841 taatataact atcatcattt gatttagatt ttctatgtca taatcttcca atatttttct
    15901 atgttcaact gcatcatctc ttagagtttc tatttctttt ttacgttttc caagagctaa
    15961 gtacagagat aagaaaaatg tacataaaat tatccaattt gataaactaa cacttatggc
    16021 tacacatcct gcataaaccc taagtataaa accaagagat attgaaaaca catctaatag
    16081 tattatattc tttagtttaa gagaatataa tatattgttt atcaaataga gactgagaat
    16141 tatagaaaga ttaaaactaa caactgttga taaacagact gaaattaaag ctaatactac
    16201 aaatagtata ttagcacttt ttttgcttat tcttccactt gccactggtc tattacattt
    16261 tttaggatgt tttttatctt tatccatgtc tatagcatca ttcagtgcat atactgatga
    16321 tgacattaga caaaaacaca caaacgcaat aaacgtattt aaaaataaat ttatatttag
    16381 tatgttgttt gaaaaaatta tagctgaaaa tacaaagaaa ttctttatat attgctttat
    16441 tctcattaac tttatataat ctgaaatttt agtaagaagc cttatacttg tattggtctg
    16501 tttcataaac ttactaccct ttcaatatta ttttttaaac aggatatgat tttatcccta
    16561 tgtttaaaat ttctataaat ccattgacat tactgattac tatagtaacc aataacagcg
    16621 atagaaatat attatacata ttcttttcat tttttctaag cgctttcgta aagtaagcca
    16681 ataaaattat aactgcaaaa ctaaaattta tagccataat acttgaattg actagattat
    16741 atcctactat accatgtaaa gttagattga atataattat tcccatacat agcttaggaa
    16801 ctcttttttc tgaattttca ataactgata aaacacaaaa acataaagct aataatgtaa
    16861 gaattactgg tattgtagca acttctccat tttgcaaaaa taaccctttt ttaatacttg
    16921 ctccaggaaa ataaaaaacc gaatacaata atctctctat aatcattgca atcttttcca
    16981 aaattggttc tccacttata aatttcgtat catactgtat tacatttcca aggttcataa
    17041 aactctcata agactttgtt gaaactacac aaatatatgc cattaggata aatgtaatta
    17101 aatgttttaa catttttcct atttttaatt taaactcaaa tatcatatta aaaaaataca
    17161 aatatatatt actaatagtt attccaaata gaggaatagc tgctaattct actaaataag
    17221 aattttttcc tttcatctta tttgcaataa ctatgaaaaa tattaatgaa aattggctat
    17281 atataaatct ctctacattt aaagtcataa ataactgtgg aaaagaaaat atcattatca
    17341 tagtaagtaa aattaaagtt aatctctgca tttttatctt tttaatatga ttaaagacta
    17401 aagttattga catagcacta gttattattt gtagacaaat tagtccaaac ccataggcac
    17461 tattaaaatc tgttgtccca ggatttgcta ttgaagtaca aaataggtat attggatatg
    17521 caaaaattga tataattgct gaaaacaata tgtgcttact attgtcttga cttatagcaa
    17581 atacatttaa attgaataaa actcctgtat ctgtatctaa caatacatca taagtattgt
    17641 ttaaatcata aaatatagta gtcttagaaa aaaatatctt agttattatt aagtaagtta
    17701 ttacaactaa tataaacaaa aacatctcgt ttttatattt taatatttta ctcatcaata
    17761 tatcaccatc cattcattat ataggatttg ctgacaccta caatttattc cttatattta
    17821 atagccatct tcataatgtt cttacttgtt ttattgtaat tgaataactc tttatttaca
    17881 accacaatat ttactttatt gatgttataa tcagtcaagt attgtttata taacatagat
    17941 tagtgttgta taaaatgaga atttgtaagc aatattaatg taaaatattt gaaaaacttt
    18001 atataaaaat atacaatgtt gcttatggaa ttaaactata acaaattaaa gcataattta
    18061 aggagacaaa attataatct gtctccttaa atattaaaac tatattttaa aacattacta
    18121 aatactatac aaatttcaaa tatagtataa aattaattag actttaacac tattagctcc
    18181 atcttcttcc cattttttaa tttcttttaa tctatctatt ataggtaaat gctgagtaca
    18241 ttcaacttca cattttccac aagatataca ttctttagct tttgccttac tattcattgt
    18301 gtaattccaa tgtcctaagc cataaactaa ctttgtcatt tcttcatcac tctttttaaa
    18361 catctgcttt tcattataaa aaagcatata ggctggggta ttaatacctt ttggacatac
    18421 tttacaataa ccacaacctg tacatatttc gttcatattc ttatttaatc tagtctcaat
    18481 atcatgtata tcctcatctg aataaattct attttcgtct gcaattttac atgcatcatc
    18541 tatatcttgt tttttattaa accctatcaa agatatactt atttgtgaaa ttcctatgtt
    18601 gaatcttaaa gctgattcta tagtactttc gccatctttt gatagaaaag aaagttcttt
    18661 attatacttt ggaatagttc caccacttaa tgggttcatt gccacaacac catatccatt
    18721 atcaacagca tatttggcac cttttagcct atatggaaag tttaatatat ttattcccat
    18781 agttacacct tcaaacttat tttcacttag aatatctata acctcatctc ctggttgatg
    18841 agatgaaaat actatatggt ctatcaatcc ttcttcttta catttcaata atccttcata
    18901 ttgacctcca ggtctcattg ctagttcgta atgttccatc tttctaatat tccaaacatg
    18961 ataaaaattt attttagata cgcctaatcg ttctattgat ttttttacag cctctatagc
    19021 tttttctgat gtatcacatg cttttggctt ttctttagtt gatacataaa aatcggtctt
    19081 accttccttt atcatttgtc taaaggctag tccaaatata tcttcacttc tgtcatcaca
    19141 ataccctggt gctgtatcaa agtaattaat acctttttca tacgcatatt tgactaaatc
    19201 agcattttct tgattacttt tttctaaatc aaaccttaat cctccatagc caactactga
    19261 aaccattttc cctgtctttc catattcaac gtatctcatt gtaaattcct ccttagatat
    19321 attaagactt aatt
//
LOCUS       DAMJVG010000078        19239 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.078, whole genome shotgun sequence.
ACCESSION   DAMJVG010000078 DAMJVG010000000
VERSION     DAMJVG010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19239)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19239)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19239
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.078"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            214..354
                     /locus_tag="PC512_002934"
     CDS             214..354
                     /locus_tag="PC512_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442666.1"
                     /translation="MEKSNTTVTKKEKIEDIGMKLEHLLSEDITFYELLLEILYKEKE
                     EN"
     gene            complement(351..722)
                     /locus_tag="PC512_002935"
     CDS             complement(351..722)
                     /locus_tag="PC512_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2442667.1"
                     /translation="MESLGDRIANLRKELDINQKELATKVGITEASLSRYENNLREPK
                     SEIIVRLAKALETSTDYLLGVNDNTKISKEDKLIIENLSVSEKTKKLLEKIYSLEKED
                     REAIEKMIDNAYLKRFLKEEN"
     gene            1271..1528
                     /locus_tag="PC512_002936"
     CDS             1271..1528
                     /locus_tag="PC512_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442668.1"
                     /translation="MIIIRSQDKTNLMQINQIKIDGSQVYAVFESKIDTVKIGDYENN
                     TRAIQVLDNIQNFIENGTKYDYITSNKVRYNVNKIFQMPAK"
     gene            complement(1638..2318)
                     /locus_tag="PC512_002937"
     CDS             complement(1638..2318)
                     /locus_tag="PC512_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HDF2442669.1"
                     /translation="MIWTFYSFICVILPCLIYQIVVIKRKNLKVEKNVMIHLVWVYIF
                     LLYIYLALSKAGIGSIWDIGRYSGLFRIDEINLIPFDSVGILTYILNIIMFMPLGFLL
                     PLIWKNFRNIINVSLTGLGFSLAIELCQLFNLRATDIDDLMMNTLGAVLGYFIWVGVN
                     NLFNLIKKKDIFPSIYKNIIQDEIAITIDDDISEKITSLYKNEAIIYLILAVLGEFLL
                     FNWSIIPY"
     gene            2578..2877
                     /locus_tag="PC512_002938"
     CDS             2578..2877
                     /locus_tag="PC512_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442670.1"
                     /translation="MKWIKWYSITCICIFIVVAFYMFIFPNKIETIDTSSAYSFVEKK
                     VPNSAVYQGYKKNPVDGTTTIYYSYDNSTHIVRLSHPEDYSRKINWDKVSNIRFD"
     gene            3201..4856
                     /gene="ilvD"
                     /locus_tag="PC512_002939"
     CDS             3201..4856
                     /gene="ilvD"
                     /locus_tag="PC512_002939"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020457899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HDF2442671.1"
                     /translation="MRSDIKKGIEGAPKRALMYGMGLTKEEIERPLIGIVNAQNEVIP
                     GHLHLDEIAEAAKNGVRMSGGLPLEFPAIGVCDGIAMGHVGMNYSLASRELIADSIEA
                     MAMAHGFDALVLIPNCDKIVPGMLMAAARLNIPSIVVSGGPMLPGKKNGKVYDFNSAM
                     EGVGACKDGTVSEEELEALAMNSCPGCGSCSGLFTANSMNCLTEALGMGIPYNGTAAS
                     HSGERKRIAKYAGMYVMELLKNDIKPRDILTIDAFKNAIAVDMAMAGSTNTVLHLPAI
                     AYESGIELNLNFFDEISEKTPCLTKLSPSGKHHIEDLHMAGGIPAIMNELSKINGINL
                     DCKTVTGKTIGENIRNCEIENEEVIHTLKNPYSNQGGLAILKGNLALNGAVVKKSAVA
                     EEMLVHEGPARVFNSEEEAVNAIFGKKINKGDVIVIRYEGPKGGPGMKEMLSPTSAVA
                     GMGLDKHVALLTDGRFSGATRGASIGHISPEAMEGGLIGLVEEGDIISINIPDKKLEL
                     KVDEVEIENRKLKFKPLEPKIKHGYLSRYAKLVTSANTGAVLK"
     gene            5200..5832
                     /locus_tag="PC512_002940"
     CDS             5200..5832
                     /locus_tag="PC512_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2442672.1"
                     /translation="MNREEKSKNSKEKIIQSAFSLFSSKGYDSTSTQDIINLSGLSRG
                     AMYHHFKTKEDILRSVTKELYSQMNNFLEHLVADDTLTANEKIIELVVHSANDYTRRK
                     MVHCSWLEKIPFALIEEVRNLNNVVAPNIAKIIKQGVENKEFSCEYPEELAEMLVFSI
                     DILLDPVLFKREYSEVCNRLDFLLFMLKKMDIPLIDEYGIQKFKDLFRQL"
     gene            5855..6667
                     /locus_tag="PC512_002941"
     CDS             5855..6667
                     /locus_tag="PC512_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2442673.1"
                     /translation="MFYNAKSCQMMIGSNTVNYIEFGSGKKTLIILPGLGDGLFPLHG
                     KIQAIAFAFRYKQFAKDYKVYVFSRKNQITEKYSTRDMAKDQADIMKKLGIMKAEVMG
                     VSQGGMIAQYLAIDYPELVEKLVLAVTSSKQNDTIQNVICSWIDMAKKQNYNDLMIDT
                     AKKSYSERYLKKYQLFIPFLGKVGKPKDFKRFIIQATSCIEHNAFSELNKITCPTLII
                     GGANDKIVGNNASFHLAEKIKKSEIFIYEGLGHATYEEAQDFNERVLEFLNK"
     gene            7181..8119
                     /locus_tag="PC512_002942"
     CDS             7181..8119
                     /locus_tag="PC512_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HDF2442674.1"
                     /translation="MNKRMKLIPYEINENLRGAKNKFPYGIKQMNARGMWDEGYTGKN
                     IVVGIIDTGCDISHPLLKGKIIGGANFSDDSNGNKNIYEDFNGHGTHVAGIIAASNYN
                     NEVMGVAPDCKLLIAKALNKDGTGTYQSIINAINFAVNNKVDIISMSLGGNKDDKNLK
                     NAVMQAVKNNISVVCAAGNNGDGDSSTSEYSYPASYAEVIEVGAINENYLVEKFSNSN
                     TTIDLVAPGRNIISTYMDNKLAIMSGTSMSAPYVSGSLALIKEWAREEFERDLDEAEL
                     YAQLIKCTRALGIPRTEQGNGYLYLNLYKYKNNSKR"
     gene            8595..9023
                     /locus_tag="PC512_002943"
     CDS             8595..9023
                     /locus_tag="PC512_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HDF2442675.1"
                     /translation="MSKIYIVYWSGTGNTEKMANFVAEGVKLKGKTPEVLDVSLLKPS
                     DLKEEDKFALGCPSMGAEQLEEGYMEPFVSELESMVSGKQIGLFGSYGWGNCEWMRDW
                     EERMQNAGATIIGGEGITAMEDPNEEAKDECIELGKTLAE"
     gene            complement(9176..9382)
                     /locus_tag="PC512_002944"
     CDS             complement(9176..9382)
                     /locus_tag="PC512_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442676.1"
                     /translation="MISHAAEICKKYKMPFIIFPTIEKKSIEEWVNIGANMLCFAQDT
                     TFITYVINQLLSFYNEIVPIQKQH"
     gene            9704..10360
                     /locus_tag="PC512_002945"
     CDS             9704..10360
                     /locus_tag="PC512_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2442677.1"
                     /translation="MTRKNNPKQAIENIITISAKLFAEKGYDKTSMQNIVDASGMSKG
                     GIFHHFSSKEDIFNVVMERRFEQIIETVNQWLGEMHGLTAKEKLRSLVRRHLTDEVIK
                     ESSNMITSAIESPHIILAFTQDNLKKLAPILANVLREGIEDRSIITEFPDECAEVILL
                     LFNFWCDTDVFQGDFPTLRKRFQFLQFLMRQIGVDILEDEIIESINIFYERKPMGQVE
                     "
     gene            10444..11523
                     /locus_tag="PC512_002946"
     CDS             10444..11523
                     /locus_tag="PC512_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2442678.1"
                     /translation="MILITLCILVAVFVLAFAGLRLIAPTIIRTSHKIEAPGIDRMEM
                     VEIGGIQQALYIRGQNADNPIILWVHGGPGNSMMPFLHLYQYEWENDFTVVNWDQRNV
                     GKTYFANDPAAVLQTMSAERVLQDVHEVTAYLKQEFNKEKIILIGHSWGTVLGTMAVQ
                     TYPEDYSAYIGIAQTVNMVDNERVGYEKTLEMVKAAGKQKDIKALEAIAPYPPAKYGP
                     SYLAALMTVRTYQSKYGLSINMDLGNIISILATPYYSLRELKNTAIVNPNAIDNQGDV
                     LRFLVEEADIRNYGVDYQVPVYYIMGENDYNSPYLPAKKFFDEIVAPDKQIFFIPDAD
                     HLPFLSKKAEFDCVLLEEIAPKLAK"
     gene            12795..14450
                     /locus_tag="PC512_002947"
     CDS             12795..14450
                     /locus_tag="PC512_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2442679.1"
                     /translation="MVDFIESNNEVQKFDWGEVMWIHEPSKTQFNRLSAGIVRFFPGN
                     CQEKHFHLSEEQLLYVIQGEGIQIIDGKKVNIKETSIVYCPPYSEHEIINTGKIDLVI
                     LITYVPHKFSSLRQIPIVFSENNIQELVNVNIIENLANQISNILKLRISVYDLKYKEI
                     FETKKENKFCDICKNIKPCTKKLVKSINNDNFEKVYHCEYGVSSLEIPIVLEENIVGY
                     IECGNFIVYKSIYIDKNLSELSSSSGIDIKYINKIYNEFPLNPKSRLYVLKENLLMMS
                     EFIQEIAKRNFFENQLSIKDEEILKSRKENIRLEEALKKANSRLLEEEYIINPIDMFN
                     NSSKEYPFELELYIEKEIKNMNLEGVYNLIDTNKLRYNDVRDTIQEMIFVLSRTVLRD
                     LEDLKLISYLRNKYNKKISLVNSDEDLWNVLFEFSKECIDKNRAFWRKDKGNLIENIN
                     EYIKKYYKENINLNSISDVFFISPNYLSSIFNERNKVSITEYINLLRIEESKKYLLDR
                     SMSVSDICKKVGFNNSSYFSQIFKKFNSITPNEYRKNMLDNKY"
     gene            14509..15261
                     /locus_tag="PC512_002948"
     CDS             14509..15261
                     /locus_tag="PC512_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HDF2442680.1"
                     /translation="MFSVIFLCIGGFLAAFVDSIAGGGGLISMPVLMAIGVPVHLAIG
                     TNKFAASAGCISSAYRYAKSGKINNNLLKKLVPFTIIGSVLGVRCVLSISEEILNVLV
                     VAMILIVAIYTFISKNLGQEDNFEAVNKKNLRLGMLMALIMGFYDGFFGPGTGTFLTF
                     GFIKIYGYDFLHASANTKILNLTSNITSLLLFMINGQVDYKIAIVFALVMIMGAYVGA
                     KVAIKKGSKMIKPIFLVMALFMVVKLVYQTLV"
     gene            complement(15787..15837)
                     /locus_tag="PC512_002949"
     CDS             complement(15787..15837)
                     /locus_tag="PC512_002949"
                     /inference="COORDINATES: protein motif:HMM:NF024729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442681.1"
                     /translation="MTEYIYYYNNKRIKKN"
     gene            16230..16523
                     /locus_tag="PC512_002950"
     CDS             16230..16523
                     /locus_tag="PC512_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDF2442682.1"
                     /translation="MGFPETFKALSDPIRREILVMLRENKMSAGEISEKFNMTNATIS
                     YHLSQLKKAGLIFETKYKNFIFYEINISVFEEVMLWFSQFMEKGEKDNEKSDK"
     gene            16504..17145
                     /locus_tag="PC512_002951"
     CDS             16504..17145
                     /locus_tag="PC512_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HDF2442683.1"
                     /translation="MKKAINKQFILSTLICFIPFIVSIYFYNRLPNEVAIHFDNYGNP
                     DNYAPKVIAAFGVPLLMLCIHLYTWFRLENEPKKANFSNVIQNLSKWGVAILSVIIQI
                     MMVLYSTGVSLESNFYTGLILGIIVILFGNYLPKCKRNYSVGIILPWTLNDEDNWNKT
                     HHLAGWIWLIGGILLIINAFINIPFYNIFVIFVIVILPFVYSYLMYKISGKNN"
     gene            17389..17721
                     /locus_tag="PC512_002952"
     CDS             17389..17721
                     /locus_tag="PC512_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HDF2442684.1"
                     /translation="MNTREMKEYRGFYNKKLSETDEFFRVFGSLDDKTYSEGAISKKN
                     KELMGLAISILSRCDECICYHIEGCINSGASKDEIIEAIKIGVIGGGSITYPNARFAI
                     KILEEFNI"
     gene            18263..18427
                     /locus_tag="PC512_002953"
     CDS             18263..18427
                     /locus_tag="PC512_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442685.1"
                     /translation="MFGKPKESVRFLDFNDVAEKFGEKKAVAIFDAIAGKKSKEHIIK
                     DIEKLVKNEV"
     gene            complement(18651..>19239)
                     /locus_tag="PC512_002954"
     CDS             complement(18651..>19239)
                     /locus_tag="PC512_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442686.1"
                     /translation="IIKKYKHDGKEYKNVVKLEETFNIKNLLYKKDDSLKVNRYFVVE
                     NNKYKLLLYESFKKEFGINSMDLAQLKLNDFGLKYFKEVDLILKKAIAINPTDSKLYY
                     AQACNYMNFDGFPGYSDTTYNALDSINKSLKYLDKNDSDYKKNASNIYNLKGVILMFH
                     KRFDEAQQYLNKALYFNKDNKDPKYNLNTIKKHLN"
BASE COUNT         7450 a         2029 c         3189 g         6571 t
ORIGIN      
        1 acaataatag atttttttgt tattattacg agttttttat tgcaactgta gaataaaagt
       61 attattatat aattaagata attatctagg gaaattttgg ataatcaaaa tatattttat
      121 aaaatcaaaa tacaattaca taaactttat taaaaatttg ttgggaattt ctgactaaca
      181 ttaagaacgt aagtttgttg ggggatggta tatgtggaaa agtcaaacac tactgttaca
      241 aaaaaagaaa aaattgaaga tataggaatg aaattagaac atttattgag tgaagatatt
      301 actttttatg aattattact tgagattttg tataaagaaa aagaagagaa ttaattctct
      361 tctttaagga atctttttaa ataggcatta tcaatcattt tttctatagc ttctctatct
      421 tctttttcaa gagaatatat tttttctaag agcttttttg ttttttcact tactgataag
      481 ttctctatga ttaatttatc ttctttgctt atttttgtat tatcatttac gcctaataaa
      541 taatctgttg atgtttctaa tgcttttgct aatctaacta ttatttcact tttaggttct
      601 cttaaattat tttcataacg tgacaagcta gcctcagtta taccgacttt agtagcaagt
      661 tctttttgat ttatatctaa ttcttttcgt agatttgcta ttctatctcc taaactttcc
      721 atatgtacat cactccttac cgaaattata agttattttg ataaaaagta aaataaaatt
      781 accaaaaata taaaaaaaaa aggttaaaat aataaaatat attgaaaatt accatttgta
      841 tatgtataat atgaattata caaatggtaa tttgatgaga ggtggtatgt tgaaataaga
      901 aactgaatta attaataaat acatagaaag ttttgaaaac ctttaattga aatataaaca
      961 atatgtacaa aattttttgc aagtaaaatt accaaatgta taaaataaat cagtagcata
     1021 gataatttta tgctttaata cattagatta tttaatttag ttataatggt caaaaatgca
     1081 atctacaaat aaaacaaagt attatcaaaa aagtattctt taagaaaatt ttttattaga
     1141 gatgtaattg atataaataa tcgtattaaa aaataaaata ctaagtttaa aaatttaaat
     1201 aatctataaa tcaattataa aatattattt cttagaaatt aaaatgaatt aagtaaatgg
     1261 aggaattgat atgataataa ttagaagtca agataaaact aatttaatgc agataaacca
     1321 aattaaaata gatggtagtc aagtttatgc agtatttgaa agtaaaattg atactgtaaa
     1381 aataggagat tatgaaaata atacaagagc tatacaagtg ttggacaata tacaaaactt
     1441 cattgaaaat ggaacaaaat atgattatat aacatcaaat aaagtcagat acaatgttaa
     1501 taaaatattt cagatgccag ctaaatagtg agtgtgcatt ttaatttaat aactaaagcc
     1561 cactttcttt tgtggtatga aagagggctt tacatatttg taaatatcga agtacacttg
     1621 ttttatcaat aaattattta ataaggtata atggaccaat taaacaataa aaattctcct
     1681 aaaacagcaa gtattaaata tataatagct tcatttttgt aaagagaggt aattttttcg
     1741 cttatgtcat catcaattgt aatagcaatt tcatcttgaa taatattttt atatatagat
     1801 gggaaaatat cttttttctt tataagatta aataaattat ttacacctac ccatataaaa
     1861 tatcctaaaa cagcacctaa tgtgttcatc attaaatcat caatatctgt agctcttaag
     1921 ttaaacaatt gacaaagttc aattgctaat gaaaaaccta atccagttaa tgaaacattg
     1981 ataatatttc taaaattttt ccaaattaaa ggtagtaaaa atcctaaagg cataaacata
     2041 attatattta aaatatatgt taagatgcca actgagtcaa aaggtattag atttatttca
     2101 tcaattctaa aaagcccact ataccttcct atatcccata tgctaccaat tccagcttta
     2161 ctaagtgcta gatagatata taataaaaaa atatataccc atactaaatg tatcattaca
     2221 ttcttttcaa ctttcaaatt ttttcgtttt ataacgacta tttggtatat taagcatggt
     2281 aatataacgc aaataaatga ataaaatgtc catatcattt tattttgtcc cctttcaaat
     2341 ttatgttttt agttttataa gtactatctt tatattaaac tgtaagtttt aaaaatcttt
     2401 taataaaatc ttaaaaattt attaatttat aaaaatatat tattaagatt aaaaaatata
     2461 tataatcaaa gtttctacaa ttatatagtt agggatataa aaattttatc gtatgcataa
     2521 atattataaa tatatggaaa taataatagt atattttggt aaagtaggag gaattttatg
     2581 aaatggatta aatggtatag tattacatgc atatgtattt ttatagtagt agctttttat
     2641 atgtttatat ttcctaataa aatagaaact attgatactt catctgcata tagctttgtt
     2701 gaaaagaaag taccaaatag tgctgtgtat caaggataca aaaagaatcc agttgatggt
     2761 actactacaa tttattacag ctatgataat tcaactcata tagttagatt atcacatcca
     2821 gaagactatt caaggaagat taattgggat aaagtttcaa acatcagatt tgattaatct
     2881 ttaatattta taaaagtcta tatatctaag gcaaatatat tattaatctt attcatagtt
     2941 gagcactttc tattatagaa gtgcctcttc tgatttatat cataaaatat tactcaacaa
     3001 tttgtaaaat atattagttt ataaaatata ttgaaaagat aatattatat aatacaattg
     3061 tgtaagatat tgataaaaaa tcgtaataaa ttttcattag tatatgctaa tattttttta
     3121 caattttcgt aattaattaa tagaaaaata tattataata atattatgaa aatttaaaaa
     3181 agtaagaaag aggtaatatt atgagaagtg atataaaaaa aggaatagaa ggagctccaa
     3241 agagagcgtt aatgtatgga atgggtctta ctaaagaaga aattgaaaga ccattaatag
     3301 gtatagtaaa tgcacaaaat gaggtgattc ctggtcatct gcatcttgat gaaatagcag
     3361 aagctgcaaa aaatggagta agaatgagtg gtggtttgcc attagaattt cctgctatag
     3421 gggtatgtga tggtatagct atggggcatg ttggaatgaa ttattccctg gcttcaagag
     3481 aattaatagc agattcaata gaagctatgg ctatggcaca tggttttgat gctttggtac
     3541 ttatacctaa ttgtgacaag atagtgccag gtatgttaat ggctgctgca agacttaata
     3601 taccaagtat tgttgtgagt ggagggccta tgcttccagg taaaaaaaat ggaaaagtat
     3661 atgattttaa ctctgcaatg gagggtgttg gagcatgtaa agatggaaca gtaagtgaag
     3721 aagaattaga agcgttagcc atgaactctt gtcctggatg tggttcatgt tctggtcttt
     3781 tcacagcaaa tagcatgaat tgtttaacag aagctttagg catgggtata ccatataatg
     3841 gtactgctgc gtcacattct ggagaaagaa aaaggatagc aaaatatgca ggtatgtatg
     3901 ttatggagtt acttaagaac gacataaaac ctagagatat tttaacaata gatgctttta
     3961 aaaatgctat agctgtggat atggcaatgg ctggttctac aaatacagta cttcacttac
     4021 ctgcaatagc ttatgaatca ggaatagagc ttaacttaaa tttttttgat gaaataagtg
     4081 aaaaaactcc ttgtttaaca aaattaagtc caagtggaaa acatcatatt gaagatttac
     4141 atatggcagg aggaatacca gctataatga acgaactttc aaagataaat ggaataaatt
     4201 tagattgcaa aaccgtaaca ggcaagacta taggggaaaa tataagaaat tgtgaaatag
     4261 aaaatgaaga agtaatacat acattaaaga atccatatag taaccaaggt gggcttgcaa
     4321 tattgaaagg aaatcttgct ctaaatggag ctgttgtaaa aaagtcagca gttgcagaag
     4381 aaatgttagt tcatgaagga ccagcaagag tttttaattc agaagaagaa gctgtaaatg
     4441 ctatttttgg taaaaaaata aacaaaggtg atgttatagt tataagatat gaaggtccaa
     4501 agggtggtcc aggaatgaaa gaaatgctat ctcctacatc agcagttgca ggaatgggac
     4561 ttgataagca tgtagcactt cttactgatg gtcgtttttc aggagcaact agaggagcat
     4621 ctataggcca tatttctcca gaagctatgg aaggtggttt aatcgggtta gttgaagaag
     4681 gagatataat ttctataaac ataccagaca aaaaattaga gttaaaagta gatgaagttg
     4741 aaatagaaaa tagaaaatta aaatttaaac ctttagaacc gaaaataaag catggatact
     4801 taagtagata tgctaaactg gtaacatcag caaatacagg agcagtttta aaatagtaga
     4861 ctatatttat gtaaattaga aaaagttaag aaaatattaa ttggatatct taggtgttat
     4921 agcactaatg aggtatcctt tttattttgt atgaaaaaca cagcaaaatc ttgattatct
     4981 ttgaaaacaa tacatctcta ttataaggaa tacgagtaca gcatagagat gtatctttta
     5041 gaccttgttg aggtaataca actttttaaa agtttgatgt ggaatgcttt tcgttccatc
     5101 tgaactatga agaaattgaa agtcagttaa ttcttgacat aataaatatt aaaatgtata
     5161 ataaaaaaca aacagacagt ctgtttttag gagggaaata tgaatagaga agaaaaaagt
     5221 aaaaatagta aagaaaaaat tatccaatca gcattttcac tattttcgtc taaaggatat
     5281 gattcaacat ctacacaaga tattatcaat ttatctggtc tatctagagg tgcaatgtat
     5341 catcacttta aaactaaaga agatatactg agaagtgtca caaaagaact ttactcacaa
     5401 atgaataatt ttttagagca tcttgttgct gatgacaccc ttacagcaaa tgaaaaaata
     5461 atagaattgg ttgttcatag tgcgaatgat tacacacgta gaaaaatggt acattgtagc
     5521 tggttagaaa aaatcccatt cgctttaata gaggaagttc gtaatctcaa caatgtagtt
     5581 gcacccaata ttgctaagat aattaaacaa ggtgttgaaa ataaagaatt ttcttgtgaa
     5641 tatccagagg aattagctga aatgctcgtt tttagtattg atattttact tgaccctgta
     5701 ttatttaaac gtgaatacag tgaagtatgt aataggttgg attttttatt attcatgtta
     5761 aaaaaaatgg atattcctct aattgatgag tatggtattc aaaaatttaa agatttattt
     5821 agacaattat aataggaaaa gcgaggaata gactatgttt tataatgcaa aaagttgtca
     5881 aatgatgata ggaagtaata cagtgaatta tattgaattt ggtagtggta agaagacact
     5941 aattatttta ccaggattag gagatggttt atttccttta catggaaaaa tacaggcgat
     6001 tgcttttgct tttagatata agcaatttgc aaaagattat aaggtttatg tatttagtag
     6061 aaaaaatcaa attacagaaa aatattccac aagggatatg gctaaagacc aagcagatat
     6121 aatgaaaaaa cttggaatta tgaaagcaga agtaatgggt gtttctcaag gtggaatgat
     6181 agctcaatat ctggcaattg attatcctga gttagttgag aaacttgtgt tggcagttac
     6241 ttcttcaaag caaaatgata ctatccaaaa tgttatttgt agttggattg atatggcgaa
     6301 gaagcagaat tacaatgatt taatgattga cacagcaaag aaatcctatt ctgaaagata
     6361 tttaaaaaaa taccaattat ttattccttt tttaggaaaa gtaggtaaac caaaggattt
     6421 taaacgattt attattcaag cgacctcttg catagaacat aatgcctttt ccgaattaaa
     6481 taaaataaca tgtccaacct taattatagg aggtgctaat gataaaattg ttggaaataa
     6541 tgcttctttt catttagcag aaaagattaa aaaaagcgaa atatttatct atgagggatt
     6601 gggacacgct acatatgaag aagcacagga ttttaatgaa agagttttag agtttttaaa
     6661 taagtaaaca cctttgttaa aaatatacat atgaagattg gaaatttaat gttaaaaata
     6721 gaaacatgaa aatatgctta actggtattt ttactattca taaccaattt ttgatacatt
     6781 atctactata aatacaaata tagcttcaat gtgattatat attagtgtat tggtaaagca
     6841 cttatacaaa cagaggaatt ttgtaaattc atattatacc cacatttgtt aacttatgaa
     6901 aatataatca aaatttttat gagattttta tataaaaaat ataatgtttg tatacaaaaa
     6961 tattgaagat attttagtaa gttttgtata taagcaaaca tgtatttttt aatatagtta
     7021 tctaaatatt attttatata caataaaata tgactcctaa aaataaaaaa tatatcataa
     7081 atataaataa gtagatatag gttttaattt gatttataaa cctattataa aataaaattc
     7141 atgattttta taagcaataa aatttttagg aggatatatg atgaataaaa gaatgaaact
     7201 aattccatat gaaataaatg aaaatctaag aggtgcaaaa aataaattcc catatggaat
     7261 aaaacaaatg aatgctaggg gaatgtggga tgaaggttat actggtaaaa atattgtagt
     7321 tggtataata gatacaggtt gtgatatatc tcatcctctt ttaaaaggaa aaataattgg
     7381 tggtgcaaat tttagtgatg acagtaatgg aaataaaaat atatatgagg attttaatgg
     7441 tcatggaact catgtggcgg gtattatagc tgcatctaat tataataatg aagttatggg
     7501 agtagctcca gattgtaaat tattaatagc aaaagcatta aataaagatg gtaccggaac
     7561 atatcaaagt ataattaatg ctattaactt tgctgtaaat aacaaggttg atattatatc
     7621 tatgtctctt gggggaaaca aagatgataa gaatttaaaa aatgctgtca tgcaagcagt
     7681 aaaaaataat atttctgtag tgtgtgcagc aggtaataat ggagatggtg attctagtac
     7741 aagtgagtat agttatccag ccagttatgc tgaggtaata gaagtaggtg caataaatga
     7801 gaactatttg gttgaaaagt ttagtaattc aaatactaca atagatttgg tagctccagg
     7861 aagaaatatt atatcaactt atatggataa taaacttgct attatgagtg gtactagtat
     7921 gagtgcacca tacgtatcag gctcattagc actaattaaa gaatgggcaa gagaggagtt
     7981 tgaaagagat ttagatgaag ctgaactgta tgcacaatta ataaaatgta cgagagcgct
     8041 tggaatacct agaacggaac aaggaaatgg atacttatat ttaaatctct ataaatacaa
     8101 gaataatagt aaaagataat ttttgatttg atgataaaat agctatatta tatagagtcg
     8161 agacaaataa taaaaattac ttaggtgtaa gattttacat caatgtataa aggtattaag
     8221 tgataaaatt tataaacata ttagctagtt agaattgaaa aataaatata cgatattata
     8281 gatagcacat ctggaaaagg tgtgtttttc tatgtactta tacatataaa agatttataa
     8341 gagatgcaaa agtactataa gttagaaatt tttctatgaa agattagaaa tacgatacag
     8401 tgttttgata ttataaaatg aatataaaat ataaatgata aatattatca ataagtattg
     8461 aatttcaata tcaactatga tattctatat ttagaaaaat aaagagattt cagataaaga
     8521 aatcttttgt tttttagatg ttagttagct ataactaact attgattaat taaaaaatac
     8581 tacaggaggt aaaaatgagt aaaatatata ttgtttattg gagtggaaca ggaaatactg
     8641 aaaaaatggc aaattttgtg gctgaaggtg tgaagttaaa aggtaagaca ccagaagttt
     8701 tagatgtgag cttactgaaa ccaagtgatt taaaagaaga agataaattt gcattaggtt
     8761 gcccatctat gggagcagag caactagaag aggggtatat ggagccattt gtttcagaat
     8821 tagaatctat ggtatcaggt aaacagattg gattatttgg ttcatatgga tggggaaatt
     8881 gtgaatggat gagagactgg gaagaacgta tgcaaaatgc tggtgctaca attattggtg
     8941 gagaaggaat tacagcaatg gaagacccaa atgaagaagc aaaagatgag tgtatagaat
     9001 taggcaaaac gttagctgaa taaatttgta tattataaaa atagtataaa taacaactaa
     9061 tgatgatagc agtatataat aataagagag actaatatta tgatacataa gaaaatatcc
     9121 ttaatagaga tagataaaat attagtctct tttaatataa aattagattt ataatttaat
     9181 gttgtttttg aattggtaca atctcattat aaaaagataa taattgattg ataacataag
     9241 tgataaaggt agtatcttgt gcaaaacaaa gcatatttgc tccaatatta acccattctt
     9301 caatactttt cttttctatt gtaggaaaaa taataaaggg catcttatat tttttgcata
     9361 tttcagcagc atgagaaatc atatctttaa aacgccgcca ttggagacaa tgagcggcgt
     9421 tttggtgtaa tggctaagga gaggagggat aggaatgaat atccgagggt caaacagggc
     9481 aggcgtggcc atacctgcct tgcttacaga tataatcaaa gccggtaaag attgcaaatt
     9541 taccaagggt tccatctagg ggaaagtcgc attagtctaa ttaatacctg tctaaccacc
     9601 aaaccttatt gttttgccat aaacacaatg ttacttgaca gaagcaggaa tagcttatat
     9661 aataaaaacc aacagtcggt ttttaataag aaggagttat ataatgacta gaaagaacaa
     9721 tccaaagcaa gctattgaaa atatcattac catttctgca aagttgtttg ctgaaaaagg
     9781 atacgacaaa acaagtatgc aaaatattgt tgatgcttcg ggaatgtcaa agggcggaat
     9841 ttttcatcac ttcagttcaa aagaagatat ttttaatgtg gtcatggaaa ggcgctttga
     9901 acagataata gagacagtaa atcaatggct cggtgaaatg catggactta cagcaaaaga
     9961 gaagcttaga agtttagtta ggcggcattt aacggatgag gtgataaaag aatctagtaa
    10021 catgattaca agcgcgatag aaagtccgca tatcatactg gcatttacac aggataattt
    10081 gaaaaaacta gcaccaatat tagcaaatgt tttacgagaa ggcatagagg atagaagcat
    10141 catcacagag ttcccagatg aatgcgcaga ggtaattttg ctgctcttta acttttggtg
    10201 tgatacagat gtatttcagg gggactttcc tacacttcgt aaacggtttc aattcttaca
    10261 gtttcttatg agacaaatag gagttgatat cctggaagat gagattatag aatcaattaa
    10321 tattttttat gaaaggaaac caatgggaca ggtagagtaa caaaactaaa atagcaacat
    10381 acttttttta atgttagagg agatatctat ggctaaaaaa attcatgaaa gaaggtactt
    10441 aaaatgatat taatcacact ttgcatacta gttgctgttt ttgttctggc gtttgccggt
    10501 ttgcgtctga tagcccccac gattatacgt acaagccata aaatagaagc tcctggaatc
    10561 gaccgcatgg aaatggtgga gatcggcggc atacagcagg cgttatatat ccggggacaa
    10621 aacgcagaca accccatcat cctttgggtt catgggggtc ctggtaattc aatgatgcca
    10681 tttttacatc tgtaccagta tgagtgggaa aatgatttta ctgtggtgaa ctgggatcag
    10741 cgaaacgtag gcaaaacata ctttgcgaac gatccggcag cagttttgca gaccatgagc
    10801 gcggagcgtg ttctgcaaga cgtccatgag gtgacagcat atttgaagca agagttcaac
    10861 aaggagaaaa ttatccttat aggtcatagc tggggaacag tgctgggaac tatggctgtg
    10921 caaacctatc cggaggatta cagcgcgtac attgggattg cgcagactgt taatatggtg
    10981 gacaatgagc gcgtgggcta tgaaaagaca cttgaaatgg tgaaagctgc agggaagcaa
    11041 aaagatatca aggcgctgga agctattgca ccatatccgc cagcaaaata tggtccaagc
    11101 tatttggcag ctcttatgac agtaagaaca taccaaagca agtatgggct ttctataaat
    11161 atggatttgg gcaatataat cagtatactg gcaaccccat attattcatt gagagagtta
    11221 aaaaatacgg ccattgtcaa tccaaatgcg attgacaatc aaggtgatgt attgcggttt
    11281 ttagtggaag aagctgacat aagaaattat ggagttgact atcaggtccc tgtatactac
    11341 atcatgggag aaaatgacta taatagcccc tatcttccag cgaagaaatt ttttgatgaa
    11401 atagtggcgc cagacaaaca gatttttttt ataccagatg cagaccatct gccatttctt
    11461 agcaaaaagg cagaatttga ctgcgtattg ttagaggaaa tcgctccgaa gttagcaaag
    11521 taacaactag gacagtaacg tggatatggt ggcaatttct tttactattc cagaacgctt
    11581 cagtttgttt ccagcaactg gtttcaatga ggtgcttgag atatatctat ttagagggtt
    11641 ttaagagagg actatcactt atggacattt tgtccataag tgacggggtc agcaatcgga
    11701 aaaggtggtc atgctatgag tgaactgaga cctttatatc agacagttaa aaaccatgga
    11761 gtgattatga aaccataaga tgattcttgt aatgtacagg agtcatcttt tatatttatt
    11821 ttctttttta gatttaattc tctacttgat ttagatacaa gagaggcttc gccttgtttt
    11881 aagtatattt ttctacttat accattattt cttttttatt tgcttttcca ctttaaataa
    11941 tacaacttca acacaatttg aagctaatat cttttattga ctattgtata aagtattttt
    12001 ataatgttct tattcatata aaattttatt ccacttacta ttgaatttta ttaagaaaaa
    12061 gatttattac tttctatatg atagaaaaat aagtggtatt agttatttct aggaagagaa
    12121 tatagagtat cctatattta ttacaagatt aaaaaaagca ggtttatata ttgaagatat
    12181 aagaatgctt tcatttttgt gatataagaa acaatatgtt tgtgatataa gagacaatat
    12241 gatagataaa agaatttaat tatttcagca atataagcaa gatattaaaa taaaatcatg
    12301 aactagaaga gtgtatatac aaaatagctg agaagataga ctatttaagc aaaaaaggta
    12361 tgtaaaaaat aatttttcta aaagaatcca acagtttttt atttctataa gaaaaataat
    12421 attaattgga acaatttaat aatattcttt cttagatgta tttctatata gtattggaca
    12481 atgttatata cagttattta tatatgcaat aaaaaggaaa attatgataa catatattga
    12541 tgtaagcagt aaaaatactt tcatttatag atataattat tttgggaaaa cactgatttt
    12601 acaaaataaa aaagtaatta tagaatttat caatatatta aaaaactgaa ttgtagtaaa
    12661 ctaagtgcaa ctaaaattac aggagtatta aaagagtatg atgattttat agtaatgaaa
    12721 gttaatgatg atgatattat tttaatataa gaagggaaga aaaaatattt agacaaaaac
    12781 tacgaggtga gtttatggtg gattttattg agtcaaataa tgaagtacaa aaatttgatt
    12841 ggggagaggt tatgtggata cacgaaccat caaaaacaca attcaataga cttagtgctg
    12901 gaattgtaag attttttccg ggaaactgcc aagaaaagca ttttcattta agtgaagaac
    12961 agcttttata tgtgattcag ggagaaggaa tacaaataat tgatggtaaa aaggtcaata
    13021 taaaggaaac atctatagtt tattgcccac catattcaga acatgaaatt ataaacactg
    13081 gtaaaattga tttagtaata ttaattactt atgttcctca taaattttcg agtttgagac
    13141 aaatacctat agtattttct gaaaacaata tacaggagtt agttaatgta aacataattg
    13201 aaaatcttgc aaatcaaata tctaatatat tgaagcttag aatatctgta tatgacttaa
    13261 agtataaaga aatatttgag actaagaaag aaaataaatt ttgcgatatt tgtaaaaata
    13321 taaaaccgtg tactaaaaaa cttgttaaaa gcataaataa tgataacttt gaaaaagtgt
    13381 atcattgtga gtatggtgtt tccagtttag agatacctat agtattagaa gaaaatatag
    13441 ttggatatat agaatgtggt aattttatag tatataagtc tatttatata gataaaaatt
    13501 tatctgaatt atcaagtagt tctggtattg atataaaata cataaacaaa atttacaatg
    13561 aatttccatt aaatcctaaa agtagattat atgtattaaa agaaaattta ttaatgatgt
    13621 ctgaatttat tcaggaaata gctaagagga atttttttga aaatcaactt agtataaaag
    13681 atgaggagat attgaagagt agaaaagaaa atataagact tgaagaggca cttaaaaaag
    13741 caaatagtag attattagaa gaagagtata ttattaatcc gatagatatg ttcaataatt
    13801 cttcaaaaga atatcccttt gaattagaac tttatattga aaaagaaatt aaaaatatga
    13861 atttagaagg tgtttataat ctaatagata caaacaaatt aagatataat gatgttagag
    13921 atactattca ggaaatgata tttgtattgt ctagaacagt gcttagagat ttagaggatt
    13981 taaaacttat atcttattta agaaataaat ataataaaaa aatatcactt gtaaacagtg
    14041 atgaagattt atggaatgta ttatttgaat tttccaaaga gtgtattgat aagaatagag
    14101 cattttggag aaaagataaa ggaaatctaa ttgaaaatat aaacgaatat ataaaaaaat
    14161 attataaaga aaatataaat ttgaatagta tatcagatgt tttttttata agtccaaatt
    14221 atttgagttc tatttttaat gaaagaaata aagtttcaat aactgagtat ataaatcttc
    14281 ttaggataga agaatctaaa aaatatctgt tagatagaag catgagtgtt agtgatattt
    14341 gtaagaaagt aggttttaat aacagtagtt atttttcaca aatatttaag aagtttaata
    14401 gtataactcc aaatgaatat agaaagaata tgctggataa taagtattaa ataagattat
    14461 ataatatata ttgtaagaaa aattgaaaga gaatgatgga ggaattttat gttttcagtt
    14521 atttttttat gtataggggg gtttttagct gcttttgtag attctatagc aggaggagga
    14581 ggacttataa gcatgcctgt tcttatggca attggagtgc cagtacatct tgccattggt
    14641 acaaataaat ttgcagcatc agcaggatgt ataagtagtg cctatagata tgcaaagtct
    14701 ggaaaaatta ataacaacct tttaaaaaaa ttagtaccat ttactattat tggtagtgtt
    14761 ctaggtgtga gatgtgtatt atcaataagt gaagagatat taaatgtttt ggttgtggct
    14821 atgattttaa tagtggctat ttacaccttt atttctaaaa atttaggtca agaagataat
    14881 tttgaagctg ttaataagaa aaatttaaga ctagggatgc ttatggctct tataatgggt
    14941 ttttatgatg gtttttttgg tccaggtaca ggaacttttt tgacttttgg atttataaaa
    15001 atatatggat atgatttttt acatgcttct gcaaatacaa aaatattaaa cttaacaagt
    15061 aatataactt cattgttatt attcatgata aatggtcaag tagattataa aattgctata
    15121 gtgtttgcat tagtgatgat aatgggagct tatgtaggtg ctaaagttgc tataaagaaa
    15181 ggttcaaaga tgataaaacc aatattttta gtaatggcat tatttatggt cgtaaaattg
    15241 gtatatcaaa cattagttta gtttatagac tttttaaatt tataagtaat tgtaaagctt
    15301 ttatatttaa tctaatcata tagctttata aaaattctaa ttatcttcta atatagttca
    15361 tatataatac acatataaac tgtaatctta caatagaagg attatatatc ataaaaatat
    15421 aaccttgatt tatatatatg aaatatatgg taatttgtag gaggaatgtt tatgaacata
    15481 tcaagaagag ctatgaagat aattgaactg gcacaaaaaa ttgctaataa aagaggtgta
    15541 acagtacaag acgcttggaa tgatgcgatg aaagaatata aagaaaaata tgaatatgtt
    15601 gcataagata tgcgttatat tttaaatata agaaaatata aaacaaaaaa gattgtctca
    15661 aaataagatt gtactgagac tcaaaagtta gattttatac aggaatggaa ttttcattcc
    15721 tgtattttta attttacata actttaaatt catattcaaa tctatattta acaaggctat
    15781 gctaaattaa ttttttttta ttcttttgtt attataataa taaatatatt ctgttatagt
    15841 tgtatctaat tagtagatgt ttttatgtac ttttatacag tatatttctc gtttcattct
    15901 tttctattta aataggactt aactactttt taaattgggt ttagctactt ttaatttaaa
    15961 attaaaagta ttgttatata tataagtacc tcagtcatta ggtttttgct ttaacaatta
    16021 tggtgcaata cacttttgtt aagttaaaaa aattagataa agtaagatta aataaaagcg
    16081 acttaagtaa attgagaatc ttaatatgaa aattttcaat aaatatttag aaataactat
    16141 ttagaaaaaa ttctaaatag ttattgaaat aaaatggatg ttatgttata ttctatttag
    16201 atgaaattct aaatagcgag gtgatggtgt tggggtttcc agaaacattc aaagctcttt
    16261 cagaccctat aagaagagaa atattggtta tgttgaggga gaataaaatg tcagcaggag
    16321 aaattagtga aaaatttaat atgacgaatg ctacaatttc ttatcatcta tctcaactaa
    16381 aaaaggcagg actcatattt gaaacaaagt ataagaactt tattttctac gaaataaata
    16441 tttcagtttt cgaagaggtt atgctttggt tttcgcaatt tatggagaag ggagaaaaag
    16501 ataatgaaaa aagcgataaa taaacaattt attttatcta ctttaatatg ttttatacca
    16561 tttattgtat caatatattt ttataataga ttaccaaatg aagttgcaat tcattttgat
    16621 aattatggaa atccagataa ttatgctcca aaggttatag cagcttttgg tgtaccattg
    16681 ttaatgctat gtatccattt gtatacatgg tttagacttg agaatgagcc taagaaagct
    16741 aatttttcaa atgttataca aaatttatca aaatggggag ttgctatact ttcagtaatt
    16801 atacaaataa tgatggtttt atattcaaca ggagttagtt tggagtctaa tttttataca
    16861 ggattaattt taggaataat agttatttta tttggaaact atcttcctaa atgtaaacga
    16921 aattactcag taggaataat tttaccatgg actcttaatg atgaagataa ttggaataag
    16981 acacaccatt tagctggatg gatttggctt attggtggaa tattattaat tattaatgca
    17041 tttattaata ttccttttta taatatcttt gtaatctttg taattgtaat actaccattt
    17101 gtatattctt atttgatgta taaaatttca ggtaaaaata actaatataa ttaatcacta
    17161 taataatgtt tggataagaa taatatattt cagaactgag atagataata aagaaattac
    17221 tgagatttct attttagttc tgaaaaaatc ttacttatat gataacttat tgagatttca
    17281 aaaaataata taaattaggc taatgaacat aaaatgaaaa tttgtattta atattgaaaa
    17341 tataagtaca gtgtgatact cttataagaa aaaaatagga ggtagaagat gaatactaga
    17401 gaaatgaaag aatatagggg attttacaat aaaaaattaa gtgaaacaga tgagtttttt
    17461 agagtatttg gaagccttga tgataagact tattcagaag gggctataag taaaaaaaat
    17521 aaggaattaa tgggactagc tatttcaatt ttaagccgat gtgatgagtg tatttgttat
    17581 catattgagg gttgtattaa ttctggagca agtaaagatg aaattataga agctataaaa
    17641 ataggtgtaa ttggtggagg gtctattaca tatccaaacg caagatttgc aataaaaatt
    17701 ttagaagaat ttaatatata attttgatac acgtagttta tttagactaa taataatagt
    17761 ctatttaagc ctttgaaatt aagctttatt ttctaagttc acttcttatt aagtttttag
    17821 aattgcatat ataaatataa atttttaaat aatatagtag ttttaaatta tttacatcat
    17881 agattgtatt gagaatagta tattgtcatt attaaatctt ttatacattt tttattttaa
    17941 ataaattgaa tattaaggtg attatattta catatttgta tttttatgaa ctagaatatt
    18001 ctttataaat tcatagcagt tttaatagat aactttttca gatagattaa acaaagtttt
    18061 atttactgta ttctattatc agtttcctac aaattaaatt gtctattttt atttatagag
    18121 tagaataaac tgtttttgtt aagaattttg aaggtaaagc tagtttaaaa aaataaaggg
    18181 actaatttgt ctaacgttta ttggtgaaaa ataagtctat agaagttata ataaatatat
    18241 aaaaatgtat gagaggtgtt atatgtttgg taaaccaaaa gaaagtgtta gatttttaga
    18301 ctttaatgat gtagcagaaa agtttggaga gaaaaaggct gttgcaattt ttgatgccat
    18361 agctggaaaa aaatctaaag aacatattat caaagatata gaaaaattag taaaaaatga
    18421 agtttagata tttataaggt atattgagct tgagggtagc tctttatacc ttctttttta
    18481 tgatttttag ataatatttt aaaatttaaa taagaaactt attgttatag agtaatattt
    18541 atatagaaat aagtctttat aatttaaact tgtaattagt ttagtagaga ttatgattca
    18601 gtgctgaatt atacataaaa aaatatttta taaattcaaa aattaaatat ctagtttaga
    18661 tgttttttta ttgtatttag attatatttt gggtctttat tatctttgtt aaagtataag
    18721 gctttattta aatattgttg tgcttcatca aatcttttgt gaaacataag aataactcct
    18781 tttaagttat atatattact tgcatttttt ttgtagtcag aatcattttt atctaaatac
    18841 tttaaagatt tattaattga atctaaagca ttatatgttg tatctgaata accaggaaat
    18901 ccatcaaaat tcatataatt acatgcttgg gcataataaa gctttgaatc agtaggatta
    18961 atagcaatag ctttttttag tataaggtca acttctttaa agtattttag tccaaaatca
    19021 ttaagcttaa gttgagcaag gtccatacta ttaataccaa attctttttt gaaactttca
    19081 tacaataata gcttgtattt gttattttca actacaaaat atctatttac ttttagagaa
    19141 tcatcttttt tataaagaag gttttttata ttaaaagttt cttctaattt aacaacattt
    19201 ttatattctt ttccatcatg tttatatttt tttatgatt
//
LOCUS       DAMJVG010000079        19027 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.079, whole genome shotgun sequence.
ACCESSION   DAMJVG010000079 DAMJVG010000000
VERSION     DAMJVG010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19027)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19027)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19027
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.079"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            100..1701
                     /locus_tag="PC512_002955"
     CDS             100..1701
                     /locus_tag="PC512_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp11"
                     /protein_id="HDF2442687.1"
                     /translation="MKMNKKILSLGLAVSLILVNFKSVNASSVVEKIYGKDRYETAAK
                     IADKQTYETVILVNTEKSLADGLSASGLSGATKAPILFTQQNKIPADTNRCLKNIKKA
                     YIIGTEDTISKSVEKELDSKNIEVKRIGGEDRLKTSYLIAKEIATIKKVDKVLLTNAY
                     SGEADAMSVSSVATRDGAPIILTDGKSVPFDVKNIQSYCIGSEEIMSNPLVKNTNSVR
                     IEGTDRFETNKNVIDYFFNSADGFYVSDGYQLVDAIAAAPLTKNSPMVLVNDGSDKTV
                     LEGAKNITSVGEINEKVIQQCINASNSNGQPPTITVGSTEVYKGEKFDTGKLNIVAKD
                     NTGKVLPIEVDGFIDTNRVGTYILTLKATDEWGKSTGKRVEIKVLDDKSHDYNSPEFK
                     KMVSTEMYNLINSYRKEKGKEPLLVSSRLEGMANAWSKYMMDKKVFAHYIDGKNAPQV
                     FSEFGMRSEENIAYIYIDSKNVQTTQDAKDLAKAIFEVWKKSPEYNANMLSNEFYSTG
                     FGLYILSDGQVHATQEFLNGNEGSL"
     gene            1920..3518
                     /locus_tag="PC512_002956"
     CDS             1920..3518
                     /locus_tag="PC512_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HDF2442688.1"
                     /translation="MKVNKRVLSIGLTISLIMAGAPNINALSSIEKIQGKDRYETSAL
                     IADKQIYDTIILVNTDNSIVDGLSASGLSGVAKAPIMLVQRDKIPTDVEKRLKDVKNA
                     YVIGTEDTIGKSVENQLKNKGIEVKRIGGEDRIKTSYLIAKEISAIKPVNDGDKVFLV
                     NGYTGEADAMSVSSVAARDGVPVILTDGKSIPFKVDGVQCYSLGSEEIMSNELVSKTN
                     SVRIAGKDRFETNKKVIQRFYKGTKKFYVSQGYKLVDAVAGSPLAKDKPIVLVNDGSD
                     KSVLRGADEVTSLGGMDKKVVDQCISSASDKNTMPTITANDVEISVGDKFDNSMLNIV
                     ATDYYGNDLKANIKGNVDINKAGTYVLNISVVDNLGQKSEISVNVKVVVNASTKDSNS
                     YEFKAMVSNEMYDLVNSYRKEKGKKSLRELDSLAGMANAWSKYMEDKKVFAHEIDGKN
                     AAEVFFGFGARSGENIAYLPMNVKSVYTSKDAKEMAESIFDLWKKSSKYNENMLKEEF
                     YSFGFGMHVSSKGEVNATMEFLNS"
     gene            3808..6006
                     /gene="slpA"
                     /locus_tag="PC512_002957"
     CDS             3808..6006
                     /gene="slpA"
                     /locus_tag="PC512_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein SlpA"
                     /protein_id="HDF2442689.1"
                     /translation="MNKKNLAMAMAAVTVVGSAAPIFADTTVKEEGYTVVQDKYEKLL
                     KELKAKIKDGTITSVGVEFDGKPITTLAPKADGSDKDAIAEQLETLTKNQLKGLGDGK
                     YVDFKITYGAKAEVPAASLSADDIQKYADQINASEKILVEVAAGSEAGIAKFDSVNNK
                     VIAGDAPLKVKDAVKATVTTNGSNKKVLTISAAAGLSGFSYGTLKDTGASSSDVDAIT
                     LDTTNATITEGDTKVLDFDNSFKFNESTKKVGSLVTPNTTNTPADPGTKTTVRVIKAV
                     EKTIDVSSNSTTKAKDLAKQYVFTDVSDTDPESLSYMLKNINDGKVAVKNSDGDYEVT
                     IFPEGKRLNTLSASSAKTILGDKDTPAKIVLKASTTKKLADYIDDLITYNNSYSNVQT
                     VAGSDRIETAIELSRKYYNSTDKNALYGDPVNNVVLVGSQAIVDGLVASPLAAEKDAP
                     LLLSSKDKLDSSTRAEIKRVMDLNSSTGIKNNKEVFIAGGVNSISKDVENELKDMGLK
                     VTRLSGDDRYETSLAIADEIDINDKAYVVGGTGLADAMSIAPVASQIKDGEATPIVVV
                     DGKSDKLSKEAEDFLDDAQVDIIGGENSVSAKMEDYIDDATGKSPERISGADRQATNA
                     EVIKEYFDKDGVSNYFLAKDGSTKEDQLVDALAAAAVAGNYGSKHNEDGDITTDASPA
                     PIILATDNLSAEQHVAVSKTATTNGAKNLVQVGQGIADSVVSKLKDLLDM"
     gene            6252..8594
                     /gene="secA"
                     /locus_tag="PC512_002958"
     CDS             6252..8594
                     /gene="secA"
                     /locus_tag="PC512_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HDF2442690.1"
                     /translation="MSVLDVILDKTDELEIKKLNNIVDKIDALEDKIQILDDEALKNM
                     TNVFKDKLSKGETLDDILPEAFAVVREVSKRILGMRQYRVQLIGGIVLHQGKIAEMRT
                     GEGKTLVGVAPVYLNALTGKGVHVITVNDYLAQRDKELMQPVYEFLGLTVGVIINGQQ
                     PVERKLQYQCDITYGTNNEYGFDYLRDNMVTQKSEKVQRELNFAIVDEVDSILIDEAR
                     TPLIIAGGGDEGTKLYELANAFIKNIRDEDFEMDRKDKTIALTASGLSKAEKFFGIEN
                     ITHIDNIEIFHHVNQSLRAHKLMNIDVEYVVRDNEILIVDEFTGRIMDGRRFTDGLHQ
                     AIEAKEGVKINDESKTMATVTFQNFFRLYSKLSGMTGTAKTEESEFEATYKINVVQIP
                     TNKPVIRADLHDKVFKTERAKYNAVVEEIIRINKTKQPVLVGTVSIEKSEKLSKLLKK
                     KGVKHEVLNAKQHDKEAEIISKAGKLGSVTIATNMAGRGTDISLGAGDKEEEEKVKEL
                     GGLYVIGTERHETRRIDNQLRGRSGRQGDPGTSRFFVSLEDEVIKLYGGKSIEKILKR
                     MNANEDDALESKALNRAIERAQKGIEGKNFEQRKNVLKYDDTINEQRKVIYDERNKVL
                     DGSDIEEEIQKMVMDIITEAAEKYLKKFRDYHGYFKYLYNTFMPADTLLIPDLDKKNV
                     EEIVNQTYQISKRVYDLKKMMIGIEELAQLEKRVLLQVVDTYWVDHIDAMDQLRQYIG
                     LKSYAQKDPFKEYAIEGYEMFEALNRNIRITTVQYLYKFN"
     gene            9008..10879
                     /locus_tag="PC512_002959"
     CDS             9008..10879
                     /locus_tag="PC512_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HDF2442691.1"
                     /translation="MNRKNLYVIMAAAMVSTSVAPSFAAEATQVKKQTITKKEATELV
                     SKVRELMAQRYTGGSQVGQPIYEIKVGETSSQLKIITNIDELEKLVNALGENKELLVT
                     IADKGHTTNSANEVVAEAIEKYENSADLSAEANSITEKAKTEATGIYGVATVEASYDS
                     TKDKLVITLKDKTDVVTSKTLQIGIGDEKVDLTANPVDIAGTNLDPSAEGFRVSKINK
                     LGVEGAKNIADIQLAEITIKNSDLNTVSPQDLYDGYRLTIRGNTIANSVGKSISDISS
                     KDSETGKYKFTVKYTDTSGKAIELTVESTNDKELKDVKDALNGNTKVNLIAGEDRYAT
                     AVAIAKETEYTDNIVIVNSNKLVDGLAATPLAQSKKAPILLASDNEIPKVTLDYIKEI
                     IKKSPSAKIYIVGGESAVSNTARKQLESVTKNVERLAGDDRHTTSVAVAKAMGSFKEA
                     FVVGAKGEADAMSIAAKAAELKAPIIVNGWNDLTADAIKLMDGKEIGIVGGSNNVPSQ
                     IENQLADIDKDRKVQRVEGETRHDTNAKVIETYYGKLDKLYIAKDGYGNNGMLVDALA
                     AGPLAAGKGPILLAKNDITNSQKNTLDKKLNLGAEVTQIGNGVELTVVQKIGKILGW"
     gene            10988..11695
                     /locus_tag="PC512_002960"
     CDS             10988..11695
                     /locus_tag="PC512_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HDF2442692.1"
                     /translation="MIEATLFFSPHQDDETLSMGSAIIEHVERSDTHVILCTDGSKSI
                     IRKVLDDGGSCSYHIKDVHKYSLSESDFSKNRDEEFKNSCKAMGVKENNIHIENNRAH
                     DGELSKEKARDIMLKYLEKYPDAKVKTVTPYKALGIHEDHRALGEAALELYREGKIKD
                     LRFYVEPYDYNDFKKVNPNVRVWKVLSSQEEKLLNAMDAYKKWNPENGNYAIGYHSVK
                     SHFDELKSNKIQYVHAP"
     gene            11728..13860
                     /locus_tag="PC512_002961"
     CDS             11728..13860
                     /locus_tag="PC512_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HDF2442693.1"
                     /translation="MKISKRIMSLLTATFFIFALSINIADASSKESLVGSGRWETAIK
                     ISQNGWKDATNAILVNDNSIADALSATPFAKLKDAPILLTQSDKLDSRTKAELKRLGV
                     KNVYLIGGMNTLSTNIEKQLKSENMTFERISGNSRYETSLKLAERLDKEKSISDIVVV
                     NGEKGLADAVSVGSAAAQENMPIILSDPNNGIKVANSFISSKNIKKSYIIGGTYSVSS
                     SIEQSLPNVKRLSGNNRNETNAKVLEEFYKNTDLKNAYITKDGMKKQGDLIDSLAVGV
                     LAAKNSSPVVLVGNSLDSSQYDVLNTKSFDNIVQVGGNGNEDAVKDILDLQEETIYRV
                     KTADELDVALRKADANDIITFKPDDNKKITSSFSIETKKAITVELEGLYTQTITVNMP
                     NGELTNKGTLDGTVKIMDIKNGTFINEGDINDIDIYDPNGCKIENKSGGDIWVLTISS
                     SAKDVNIENKGDISKVTNNSTSVIIRNSGNIDTLSGINAPAISGNKPRVDDTDKDEKR
                     ASGIYPTSEPLSPARAGYISVKIFTKPEDTNYKIYYRVVSSRPSALYIGDRIDTSDWT
                     AVPSSVLPFTIKAENGYYIEAVEINSDTKKVSRWGKSDYIDDGFYLKSETAKGLSADI
                     DFDGDYVKLTATGADSGCTVYYRIVSKKPVSMNVGDKVTISDWDEITTNRVRIEANDV
                     KDKYIELVELDDSTNKVTRWGASDKVVE"
     gene            complement(13913..14308)
                     /locus_tag="PC512_002962"
     CDS             complement(13913..14308)
                     /locus_tag="PC512_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HDF2442694.1"
                     /translation="MILKKHRETILYLFFGAFTTLVNIVSYLFFTRVILFNFMVANAL
                     AWILAVLFAYVTNKFFVFESKRIELIFLFKEFLFFVSFRLLSGIIEMIIMYIMIDLFF
                     VNDITVKVFTNIIVIVLNYLFSKMIIFRK"
     gene            14535..16946
                     /locus_tag="PC512_002963"
     CDS             14535..16946
                     /locus_tag="PC512_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding cysteine protease Cwp84"
                     /protein_id="HDF2442695.1"
                     /translation="MRKYKSKNLSKLLALLTVCFLIVSTIPVSAENHKTLDGVETAEY
                     SESYLQYLEDVKNGDTAKYNGVIPFPHEMEGTTLRNKGRSSLPSAYKSSVAYNPMNLG
                     LTTPAKNQGSLNTCWSFSGMSTLEAYLKLKGYGTYDLSEEHLRWWATGGKYGWNLDDM
                     SGSSNVTAIGYLTAWAGPKLEKDIPYNLKSEAQGATKPSNMDTAPTQFNVTDVVRLNK
                     DKETVKNAIMQYGSVTSGYAHYSTYFNKDETAYNCTNKRAPLNHAVAIVGWDDNYSKD
                     NFASDVKPESNGAWLVKSSWGEFNSMKGFFWISYEDKTLLTDTDNYAMKSVSKPDSDK
                     KMYQLEYAGLSKIMSNKVTAANVFDFSRDSEKLDSVMFETDSVGAKYEVYYAPVVNGV
                     PQNNSMTKLASGTVSYSGYINVPTNSYSLPKGKGAIVVVIDNTANPNREKSTLAYETN
                     IDAYYLYEAKANLGESYILQNNKFEDINTYSEFSPCNFVIKAITKTSSGQATSGESLT
                     GADRYETAVKVSQKGWTSSQNAVLVNGDAIVDALTATPFTAAIDSPILLTGKDNLDSK
                     TKAELQRLGTKKVYLIGGENSLSKNVQTQLSNMGISVERISGSDRYKTSISLAQKLNS
                     IKSVSQVAVANGVNGLADAISVGAAAADNNMPIILTNEKSELQGADEFLNSSKITKSY
                     IIGGTATLSSNLESKLSNPTRLAGSNRNETNAKIIDKFYPSSDLKYAFVVKDGSKSQG
                     DLIDGLAVGALGAKTDSPVVLVGNKLDESQKNVLKSKKIETPIRVGGNGNENAFNELN
                     TLLGK"
     gene            17243..18820
                     /locus_tag="PC512_002964"
     CDS             17243..18820
                     /locus_tag="PC512_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp5"
                     /protein_id="HDF2442696.1"
                     /translation="MKAPKTILTILTIALTLSSISIIPSYALTEEKLIGNGRYETAVK
                     ISQKAYSSSPNVVLVNDNSLADALSATPFAKAKGAPILLTESDKLDDRTEKEIKRLGA
                     KDIYLIGGTAVLNKDIENKLKSNGLNVERINGKDRYETSLILANKLKDIKDIKEVAVV
                     NGEKGLSDAVSVGAPAAQNKMPIILSSPKDGVEAFDKFIRDEKVIKAYVIGGTNSVSR
                     AVEKSLPNAERVSGKDRNETNAKVIEKFYTDTNLSNLYVTKDGSKNENQLIDSLAVGV
                     LAAKNESPVVLVGNKLNTKQRDILSTKKLNTITQVGGNGNEEAFDEIKSLQEKTVFEA
                     KTVEELTDMINIASPNDIINFKPKENTVNEAFRMVTNKPITVNIKGDCSKTLTVDMPN
                     GEVNNYATLVNVIVRNIGEGGFNNHDTITILSVRDKNGRVIENTRNSDIDTLMILASA
                     NDTKLINDGYIGKLIDNSSNSDITNNGTIDKKVNQVEDLEAKVDSIEKAIDSISQKVN
                     KIQDILDKLGFLKKFLS"
BASE COUNT         7743 a         2126 c         3585 g         5573 t
ORIGIN      
        1 ttcatatcat atatactcta taatatatgg aaaataaaga gaaaataaat ggaaaataat
       61 cacaatataa atataaaata taaaaatcat cagggggata tgaaaatgaa caaaaaaata
      121 ttatcattag gtctagcagt atcattaatc ttagtaaact tcaaaagtgt aaatgcatca
      181 tcagtagtag aaaaaatata cggtaaagat agatatgaaa cagcagcaaa gatagctgat
      241 aaacagactt atgaaacagt aattttagta aatacagaaa aatcacttgc agatggatta
      301 agtgcaagtg gattatcggg agctacaaaa gctccaatac tatttacaca acaaaataag
      361 ataccagcag acacaaatag atgtctaaaa aatatcaaaa aagcatatat aataggtaca
      421 gaagatacta taagtaaatc agtagaaaaa gaactagatt ctaaaaatat agaagtcaaa
      481 agaattggtg gagaagatag actaaaaaca agctatttaa tagctaaaga aatagcaact
      541 ataaaaaaag tggataaagt actattaact aatgcatata gtggagaagc agatgcaatg
      601 agtgtatcat cagtagctac tagagatgga gctccaatca tacttacaga tggaaagagt
      661 gtgccttttg atgtaaaaaa tattcaatca tattgtatag gttcagagga gataatgagt
      721 aatcctctag ttaaaaatac aaactcagta agaatagaag gaactgaccg atttgaaact
      781 aacaaaaacg taatagacta cttttttaat agtgcagatg gattctatgt atcagatgga
      841 taccaattag tagatgcaat agcagctgca ccacttacta aaaactctcc aatggtacta
      901 gtaaatgatg gaagcgataa aactgtatta gaaggagcta agaatataac ctctgtaggt
      961 gaaataaatg agaaggtaat acaacagtgt ataaatgctt caaattcaaa tgggcaaccc
     1021 ccaacaatta cagttggaag tacagaggta tataagggtg aaaagtttga cactggcaag
     1081 ttaaatatag tagctaaaga taacacaggg aaggtattac caatagaagt tgatgggttt
     1141 atagatacaa atagagtagg tacatacata ttgacattaa aagctacaga cgaatgggga
     1201 aaaagcacag gaaaaagagt agaaataaaa gtgttggatg acaaatctca tgattacaac
     1261 agcccagaat ttaaaaaaat ggtatctact gaaatgtata acttaatcaa ttcctataga
     1321 aaagaaaaag gcaaagagcc tttgctagtg tctagtaggc tagaaggtat ggcaaatgca
     1381 tggtctaagt atatgatgga taaaaaagta tttgcacatt atatagatgg aaaaaatgct
     1441 ccacaagtat tttctgaatt tggaatgaga agtgaggaaa atatagcata tatttatata
     1501 gattctaaga acgttcaaac gacacaagat gcaaaagact tggcaaaggc tatatttgag
     1561 gtgtggaaga agtctccaga gtacaatgca aacatgctta gtaatgagtt ttatagtact
     1621 ggatttgggc tttatatatt atctgatggt caagtgcatg ctactcagga gtttttaaat
     1681 ggaaatgaag gtagcttgta aaaaattcca taaatcttgt ttttttgtta atttactgat
     1741 attataaaat gaaaatcaca tctaaagtac tttttgtaat ctgttttgtt attgctttac
     1801 aggctatggt attttaggtg ttttttgttt tagtagttta tagattttga gggaatcact
     1861 actgaggatg taatttatga ttagctgaat tatataaaaa aattagtagg aggagtttga
     1921 tgaaggtaaa taagagagta ttatcaatag gattgacaat atcattaata atggcaggag
     1981 caccaaatat caatgcactt tcgagcatag aaaagataca ggggaaagat agatatgaga
     2041 cttctgcatt gatagcagat aaacaaatat atgatacaat catattagta aatactgata
     2101 attctatagt agatggatta agtgcaagtg gattatctgg agttgcaaaa gctcctataa
     2161 tgttggtgca aagagataag ataccaacag atgttgaaaa aagactaaag gatgttaaga
     2221 atgcttatgt tataggtaca gaggatacaa taggtaaatc tgtagaaaat caacttaaga
     2281 ataaagggat tgaagttaaa agaattggtg gggaagatag aataaagact agctatctta
     2341 tagctaagga gatttcagct attaaaccag taaatgatgg tgataaggtt tttcttgtaa
     2401 atggatacac aggtgaggct gatgcaatga gtgtatcttc tgtagctgct agagatggag
     2461 ttcctgtgat acttactgat ggaaagagta taccatttaa agttgatggc gttcagtgct
     2521 attctcttgg gtcagaggag ataatgagta atgaacttgt gagtaagact aattcagtta
     2581 ggattgctgg taaggatagg tttgaaacta ataagaaggt tatacaacgc ttttataaag
     2641 gaacaaagaa gttttatgtt tctcaagggt ataagttagt tgatgctgtg gctggttctc
     2701 cgttggctaa ggacaaacct atagtacttg ttaatgatgg aagtgataag agtgtgctta
     2761 gaggtgctga tgaagttact tctttaggtg gaatggataa gaaggttgtt gaccaatgta
     2821 ttagttctgc atctgataaa aatacaatgc ctacaattac tgctaatgat gtagagattt
     2881 ctgtagggga taagtttgat aatagtatgt tgaatatagt tgctactgat tattatggaa
     2941 atgatttaaa ggcaaatatt aaaggaaatg ttgatattaa caaggctgga acatatgttt
     3001 taaatataag tgtagtggat aatttaggtc agaagagtga gattagtgta aatgttaagg
     3061 tagttgtaaa tgcgagtaca aaagactcta atagttatga gtttaaggct atggtatcta
     3121 atgagatgta tgatttagtt aattcatata gaaaagaaaa aggcaagaag agtttaagag
     3181 agttagactc tttagctgga atggcaaatg catggtctaa atatatggaa gataagaagg
     3241 tatttgccca tgagattgat ggtaaaaatg cagctgaagt attttttggc tttggagcaa
     3301 gaagtggtga aaatattgca tatctaccaa tgaatgttaa atctgtttat acttctaaag
     3361 atgcaaaaga aatggctgag tctatttttg atttatggaa gaagtcttct aagtataatg
     3421 aaaatatgtt aaaagaagaa ttttatagct ttggatttgg tatgcatgtt tctagtaaag
     3481 gagaagtgaa tgcgacaatg gaatttttaa atagttagat tttatattaa tttacattgg
     3541 aaaagatata gtaaatttgt aaaaataaat atataaaatt aaaataactt ataaaattat
     3601 aaaaaataat ttaaaaataa taaaaatgat gaaaaaacaa ttaatttgtt ggaaaaaact
     3661 tcaattaatt ttgcataaat tattgaattt atattttata tagtctatca taagagtgtg
     3721 agaaatattt ggattatatg aacatggaaa tttaatgtac ataattaaag agatgtaatt
     3781 aatataatgt tgggaggaat ttaagaaatg aataagaaaa atttagcaat ggcaatggca
     3841 gctgttactg ttgtaggttc tgctgctccg atatttgctg atactactgt taaagaagaa
     3901 ggatatacgg tagtacaaga caaatatgaa aaattactta aagaattaaa ggcaaagata
     3961 aaagatggaa ctattacatc agttggtgtt gaatttgatg gaaaaccaat tactacatta
     4021 gcaccaaagg cagatggtag tgataaagat gcaatagcag aacagttaga aactcttact
     4081 aaaaaccaac ttaaaggttt aggtgatgga aaatatgtag attttaaaat tacttatggt
     4141 gctaaagcag aagttccagc tgcttcatta agtgcagatg atatacaaaa atatgcagat
     4201 caaataaatg cttctgagaa aatattagtt gaagtagcag caggatctga agcaggtata
     4261 gcaaaatttg attctgttaa caataaagtt atagcaggag atgctcctct taaagttaaa
     4321 gatgcagtga aagcgactgt tactactaat ggtagtaata aaaaagttct tacaatatca
     4381 gctgcagctg gattatcagg attttcatat ggaacactta aagacacagg tgcaagttca
     4441 tctgatgttg atgcaataac tcttgacact acaaatgcaa caataacaga aggtgatact
     4501 aaagtattag attttgataa ttcatttaag tttaacgaaa gtactaaaaa agttggtagt
     4561 ttagttacac caaatacaac aaacactcca gcagatcctg gtactaaaac tactgttaga
     4621 gtgataaaag ctgttgaaaa aacaatagat gtaagttcaa attcaactac aaaagctaaa
     4681 gatttagcta aacaatatgt attcacagat gttagtgata ctgatccaga aagtttaagt
     4741 tatatgctta aaaacataaa tgatggaaaa gttgctgtta aaaattctga tggagattat
     4801 gaagtaacta tattcccaga aggaaaaaga ttaaatactt tatctgcttc ttcagctaaa
     4861 actattttag gagataaaga tactccagca aaaatagttt taaaggcttc aacaacaaag
     4921 aaattagcag actatataga tgatttaata acttataaca atagttattc aaatgtacaa
     4981 actgtagcag gtagtgatag aatagagact gctatagagc taagccgtaa gtactataac
     5041 tctactgaca aaaatgcttt atatggagat cctgtaaata acgttgtatt agtaggttct
     5101 caagctatag ttgatggatt agtagcatct cctttagcag cagaaaaaga tgctccttta
     5161 ttgttaagtt ctaaagataa attagattca tcaacaagag ctgagataaa aagagttatg
     5221 gacttaaatt cttcaacagg aataaaaaat aataaagaag ttttcatagc aggtggagta
     5281 aattctatat ctaaagacgt tgaaaatgaa ctaaaagata tgggacttaa agtaactaga
     5341 ttatcaggtg atgatagata tgaaacttca ttagcgatag ctgatgaaat agatataaat
     5401 gataaagctt atgtggtagg tggaacagga ttagcagatg ctatgagtat tgctccagtt
     5461 gcatctcaaa taaaagatgg tgaagctact ccaatagtag ttgtagatgg aaaatctgac
     5521 aagttatcta aagaagctga agatttctta gatgatgcac aagtagatat aatcggtgga
     5581 gaaaatagtg tttctgctaa aatggaagat tatatagatg atgctactgg aaaatctcca
     5641 gaaagaatta gtggtgctga tagacaagca actaatgctg aagttataaa agaatacttt
     5701 gataaagatg gagtttcaaa ttacttctta gcaaaagatg gttcaactaa agaggatcag
     5761 ttagttgatg cattagcagc agcagcagta gctggaaact acggttctaa gcataatgaa
     5821 gatggagata taactacaga tgcttctcct gctccaatta ttttagcaac tgataattta
     5881 tcagctgaac aacatgtagc tgtaagtaaa actgctacta ctaatggtgc taagaactta
     5941 gtacaagtag gtcaaggaat agctgattca gttgttagca aattaaaaga tttattagat
     6001 atgtaatata aattttatat attgaataaa aaaggtttct cttttgagaa acctttttta
     6061 ttttaaacat aaatttttat aaataaaaag aggctaatta gcctcttttt aatgtgagaa
     6121 acacttaaaa aataagatgt aattatttat ttaagtatca ttattatact ataccttaaa
     6181 ataaatgtct actattctat aattttaagg tataatagta agtggaaaat aaataaggag
     6241 gtaaattaaa tatgtcagtt ttagatgtaa tattagacaa aacagatgaa ttagaaatta
     6301 aaaaattaaa taatatagta gataaaatag atgctttaga agataaaata caaatactag
     6361 atgatgaagc attaaaaaat atgacgaatg tatttaagga taagttaagt aaaggagaaa
     6421 ccttagatga catattgcca gaagcatttg ctgttgtaag agaagtatca aaaagaatat
     6481 taggtatgcg tcaatataga gttcaattaa ttggtgggat tgtattacat caagggaaaa
     6541 tagcagagat gagaactgga gaaggaaaga ctctagtagg agtagctcca gtttacttga
     6601 atgcattgac tggtaagggg gtacatgtca tcacggttaa tgattacttg gctcaacgtg
     6661 ataaagaact tatgcaacca gtatatgaat ttttaggttt aacagtagga gtaattatta
     6721 atgggcaaca gccagtagaa cgaaaattac aatatcaatg tgatattact tatggtacaa
     6781 acaatgagta tggattcgat tatttaagag ataatatggt aacgcaaaaa tcagagaaag
     6841 ttcaaagaga actaaacttt gctatagttg atgaggttga ttcaatactt atagatgaag
     6901 ctagaacacc acttataatt gctggtggag gagatgaagg tactaagctg tatgaacttg
     6961 caaatgcttt tataaagaat ataagagatg aagattttga aatggataga aaagataaaa
     7021 ccatagcact tactgcaagt ggtcttagta aagctgagaa attttttgga atagaaaata
     7081 taactcatat agataatata gaaatttttc accatgtaaa tcaatctcta agagcacata
     7141 aattaatgaa catagatgtt gaatatgttg ttagagataa tgagatacta attgtagatg
     7201 aatttacagg aagaataatg gatggaagaa ggtttactga tgggcttcat caagcaattg
     7261 aagctaaaga gggagtaaaa ataaatgatg aatcaaagac catggcaaca gtaacatttc
     7321 aaaatttctt tagattatac tctaaattat caggaatgac aggtacagca aagacagagg
     7381 aaagtgagtt tgaagctaca tataagatta atgttgttca gataccaact aataaaccag
     7441 ttataagagc tgatttacat gataaagtat tcaaaacaga acgtgcaaag tacaatgctg
     7501 ttgtagaaga aataataagg ataaataaaa ctaagcaacc agtgcttgta ggaactgttt
     7561 caattgaaaa atctgagaaa ttatctaagc tacttaaaaa gaaaggtgta aagcacgagg
     7621 tcttaaatgc taaacaacat gataaggaag ctgaaataat atctaaagct ggtaaattag
     7681 gttctgttac aattgctact aatatggcag gtagaggaac tgatatatca cttggagctg
     7741 gagataaaga agaagaagaa aaggtgaaag agttaggtgg cttgtatgtt ataggtactg
     7801 aaagacatga gacaagaaga attgataatc agcttagagg gcgttcggga agacaaggtg
     7861 accctggaac ttctagattc tttgtaagtt tagaggatga agtaataaaa ttgtatggtg
     7921 gaaaaagtat agaaaaaata ttaaagagaa tgaatgctaa tgaagatgac gcgttagaaa
     7981 gtaaggcttt gaatagagca atagaaagag cacagaaagg cattgaaggt aaaaattttg
     8041 aacaaagaaa gaatgttctt aagtacgatg atactattaa tgagcaaaga aaagtaatat
     8101 atgatgaaag aaataaggta ttggatggtt ctgatattga agaagagata caaaaaatgg
     8161 ttatggatat tattacggag gctgctgaaa agtacttaaa aaaatttaga gactatcatg
     8221 gatattttaa gtatttatat aatactttta tgccagctga tactttatta attccagact
     8281 tagataaaaa aaatgttgaa gaaatagtaa atcaaacata tcagatttca aagcgtgttt
     8341 atgatcttaa gaagatgatg attggaattg aagaattggc tcaattagag aaacgagtat
     8401 tacttcaagt tgtggatact tattgggttg accatataga tgcaatggat caactaagac
     8461 aatatatagg tcttaaatct tatgcacaaa aagatccatt taaagagtat gctatagaag
     8521 gttatgaaat gtttgaagct ttaaatagga atataagaat aacaacagtg caatatctat
     8581 ataaatttaa ctaaaaaagt gacccattgg gtcacttttt atatattaag attaaagtga
     8641 aatttatttt acagtacaca ctcatataga taaatattta taataatgaa aaagaggctg
     8701 aacgtcagcc tcttttcctg tgtgagaaat acggaaaaaa gagatgcttg aaatttcttt
     8761 cttccattta atattatact ataaagagaa taaaaagtcc atgagttatc tttatgatta
     8821 aaaaaaaaaa ttacaatttt gttacttttt agtatacaat aataaattta aattgacttt
     8881 gttaattttt attaataaaa tatccaaata ttacaatatc tacagtttat tgaaataatg
     8941 tgtaaattat attataattg gtaaataagg aaaaatggtg aaaaccaaat tttgtagggg
     9001 gaaatatatg aatagaaaaa atctttatgt aattatggca gctgcaatgg taagtacatc
     9061 agtagctcca agttttgctg cagaagctac acaagtaaag aaacaaacaa taactaaaaa
     9121 ggaagcaaca gaattagttt ctaaagttag agaactaatg gctcagagat atacaggagg
     9181 ttctcaagtt ggacaaccaa tatatgaaat aaaagttggt gaaacttcat cacaattaaa
     9241 aataataact aatatagacg aattagagaa attagtaaat gctttaggag aaaataaaga
     9301 gcttcttgtg actatagcag ataaaggaca tacaacaaat agtgcaaatg aagtggttgc
     9361 tgaagcaatt gaaaaatatg aaaattcagc agacctttca gctgaagcta attcaataac
     9421 agaaaaagct aaaactgaag ctactgggat ttatggagtg gcaactgtag aagcttcata
     9481 tgacagtaca aaagataagt tagtaataac tttaaaagat aagactgatg tagtaacttc
     9541 taaaacgcta caaataggta ttggtgatga aaaggttgat ttaacagcaa atccagttga
     9601 tatagcagga accaatttag acccttctgc agaaggattt agagtaagta aaataaataa
     9661 attaggtgta gaaggagcta aaaatattgc tgatattcaa ttagctgaaa taactataaa
     9721 aaatagtgat ttaaatacag tttcacctca agatttatat gatggatata gattgactat
     9781 tcgaggtaat acaatagcaa atagtgtagg aaaatcaatt agtgatattt catcaaaaga
     9841 ttcagagaca ggaaagtata aatttactgt taaatatact gatacatctg gaaaagcgat
     9901 agaacttact gtagaaagta ctaatgataa agagttaaaa gatgttaaag atgccttaaa
     9961 tggaaataca aaagtcaatt taatagctgg ggaagacagg tatgcaactg ctgtagctat
    10021 agcaaaagaa acagaatata ctgacaatat agttatagtt aattcaaata aattagttga
    10081 tggattagca gcaacaccac tagctcaatc taaaaaagct cctatattgt tggcgtctga
    10141 taatgaaata ccaaaagtaa ctttagatta tataaaggaa ataattaaaa aaagtccatc
    10201 agctaaaata tatatagtag gtggagaatc agcagtatca aatacagcta gaaagcaatt
    10261 agaatcagta actaagaatg ttgaaagatt ggctggagat gatagacata caacttcagt
    10321 agcagtagca aaagctatgg gttcttttaa agaagcattt gtagtaggtg caaaagggga
    10381 agctgatgct atgagtatag ctgctaaagc tgctgaactt aaggctccta taatagtaaa
    10441 tggttggaat gatcttacag cagatgctat caagttgatg gatggaaaag agattggtat
    10501 agttggtggt tctaataatg tacctagcca aattgaaaat caacttgctg atattgataa
    10561 agatagaaag gttcaaagag ttgaaggtga aacaagacac gatactaatg ctaaagttat
    10621 agaaacatat tatggcaaat tagataaact atatatagca aaagatggat atggaaataa
    10681 tggtatgtta gtagatgcat tggcagcagg tcctctagca gcaggaaaag gaccaattct
    10741 tttagctaaa aatgatataa caaactcaca aaagaatact ttagataaaa aactaaatct
    10801 tggtgcagaa gtaactcaaa taggtaatgg ggttgaattg actgtagttc aaaaaatagg
    10861 caaaatacta ggatggtaat aatcaataat atagaaaagg attccttatt atttatagga
    10921 atctttttct atcgacataa tattcattaa agtataacat gctcttgaca gataggagga
    10981 tatgatagtg atagaagcaa cattgttttt ttccccacac caagatgatg aaacattaag
    11041 tatgggtagt gcaataattg aacatgtaga aagaagcgat acacatgtta tattatgtac
    11101 tgatggcagt aaatcaataa taagaaaagt attagatgat ggagggtcat gttcttatca
    11161 tattaaagat gtacacaagt actctttatc agaaagtgat ttttcaaaaa atagagatga
    11221 agaatttaaa aatagttgta aagcaatggg agttaaagaa aataatatac atatagaaaa
    11281 taatagagct catgatggag aattgagtaa ggaaaaagca agagatataa tgctaaaata
    11341 tttagaaaaa tatcctgatg ctaaagtgaa gaccgttaca ccatataaag ctcttggaat
    11401 acatgaagac catagagcat taggtgaagc tgcattagaa ttgtatagag aaggaaaaat
    11461 aaaagattta agattttatg tagagccata cgattataat gattttaaaa aagttaatcc
    11521 aaatgttaga gtatggaagg ttttgagtag tcaagaagag aaattattaa atgctatgga
    11581 tgcatacaag aaatggaatc ctgaaaatgg taactacgca attggatatc attctgtaaa
    11641 atctcacttt gatgaattaa aatccaataa aatccaatat gtacatgctc cataaacatt
    11701 aatataaaaa ctaggaggat atagttaatg aaaatatcta agagaataat gtcgttgttg
    11761 acagcaactt tttttatctt tgcattatct atcaatatag ctgatgcttc atcaaaagag
    11821 agtctagtgg gctctggtag atgggaaact gcaataaaaa ttagtcagaa tggatggaaa
    11881 gatgctacta atgctatact agtaaatgat aattctatag ctgatgcatt atctgcaact
    11941 ccatttgcta agttaaaaga tgcacctatt ttattaactc aaagtgataa attggatagt
    12001 agaactaaag cagaattaaa aagactaggt gtaaaaaatg tatatttaat tggaggtatg
    12061 aatactctaa gcaccaatat tgaaaaacaa ttaaaatcag aaaatatgac ttttgagagg
    12121 atttcaggta atagtagata tgaaacatct ttaaaattag ctgaaagatt agataaagag
    12181 aagagtattt ctgatatagt tgtagttaat ggagagaaag ggctagcaga tgcagtaagt
    12241 gtgggttctg ctgcagcaca agaaaatatg ccaattatac tttcagatcc taacaatgga
    12301 ataaaagttg caaatagctt tattagtagt aaaaatataa agaaatctta tataattggt
    12361 ggtacatatt ctgtatctag ttctattgaa cagagtttac ctaatgtaaa aagattatct
    12421 ggaaacaata gaaatgaaac taatgcaaag gttctagaag aattttataa aaatacagac
    12481 ttaaaaaatg cttatataac taaagatggt atgaaaaaac agggggattt gatagattct
    12541 ctagctgtag gtgtattggc agctaaaaat agctctccag ttgtattagt aggaaattca
    12601 cttgactcta gccaatatga tgtgttaaat actaaaagtt ttgataatat tgtgcaagtt
    12661 ggtggaaatg gaaatgaaga tgctgtaaag gatattcttg atttacaaga agaaactata
    12721 tatagagtta agacagcaga cgaattggat gttgctctaa gaaaagcaga tgctaatgat
    12781 attataacat ttaaacctga tgataataaa aaaattacta gttcatttag tatagaaaca
    12841 aagaaagcta taactgtaga gcttgaagga ttgtatacac aaacaataac tgtaaatatg
    12901 ccaaatggag aattaactaa taagggtaca ttagatggaa ctgtgaaaat aatggatata
    12961 aaaaatggca catttatcaa tgaaggtgat ataaatgata ttgacattta tgatccaaat
    13021 ggatgtaaaa tagagaataa aagtggtgga gatatatggg ttttaactat atctagtagt
    13081 gctaaagatg taaatataga aaataaaggt gatataagta aggttacaaa taattctact
    13141 agcgttataa taagaaattc aggaaatatt gatactttaa gtggaattaa tgcaccagca
    13201 ataagtggaa ataaacctag agttgatgat accgataagg atgaaaaaag agcaagtgga
    13261 atatatccta cttcagaacc tttatcacct gcaagagctg gttatataag tgtaaaaata
    13321 ttcactaagc ctgaagatac aaattataaa atttattata gagtagtaag cagtagacca
    13381 tctgcattat atatcggaga tagaatagat acaagtgact ggactgctgt accatcttct
    13441 gttttaccat ttactattaa agcagaaaat ggatattata tagaagctgt tgaaataaat
    13501 tctgatacta agaaagtatc tagatggggg aaatctgact atatagatga tggattttat
    13561 ttaaaatcag aaactgcaaa aggattaagt gcagatatag attttgatgg agattatgtt
    13621 aaattaacag caacaggtgc tgattctgga tgtacagttt attatagaat agtatcaaaa
    13681 aagccagtat caatgaatgt tggagataaa gtaactatat ctgattggga tgaaattact
    13741 actaatagag tgaggataga agcaaacgat gtaaaggata aatatataga actagttgaa
    13801 ttggatgatt caactaataa agtaactaga tggggagcaa gtgataaggt agtagaatag
    13861 gtatctaatg tgaaacataa aaacagactg attaataatg ggcagtctgt ttttatttcc
    13921 taaaaattat cattttacta aataaataat ttaaaactat aacaattata ttagtaaata
    13981 cttttacagt aatatcattt acaaaaaata aatcaatcat tatatacata ataatcattt
    14041 ctataatacc agaaagtagc ctaaaactga caaaaaacaa aaactcctta aacaaaaata
    14101 ttagttcaat tcttttactc tcaaacacaa aaaacttatt agtaacataa gcaaataaaa
    14161 cagcaagtat ccatgccaaa gcatttgcaa ccataaaatt aaataaaata actctagtaa
    14221 aaaataaata cgaaactata tttacaagag tagtaaatgc tccaaaaaat aaatataata
    14281 tcgtctctct atgctttttt aaaatcaaat ataatcctcc taagctaatt taatataaat
    14341 atacttaaag atactaacaa acattagtat aacacatcta ttaataaatc aatatatctt
    14401 aaaatattat aaaaataaaa ctataatatt ctataattaa tatgtactca taatccatat
    14461 tttatcaaaa taaaatatga ccttaattta gaaatctgat ataataaaaa ttaaatacat
    14521 ataagggggt aaacatgaga aagtacaaat caaaaaactt gtcaaagcta ctagcattgt
    14581 tgacagtttg ctttttaata gtgtcaacaa tacctgtctc agcagaaaac cataaaactc
    14641 tagatggagt agaaactgca gagtattctg aaagctatct tcaataccta gaagatgtca
    14701 aaaatggaga cacagcaaaa tataatggag taataccttt tccacatgaa atggaaggta
    14761 caacacttcg aaataagggt agaagtagtc ttccatcagc atataaatca agtgtagcat
    14821 acaacccaat gaatcttggt cttactacac cagcaaaaaa tcaaggaagt cttaatacat
    14881 gctggtcttt ttcaggtatg tcaacgttag aagcatatct taaattaaaa ggatatggaa
    14941 cgtatgactt atcagaagaa catttaagat ggtgggcaac tggtggaaaa tatggatgga
    15001 acttagatga tatgtcaggg agttcaaatg taacagctat aggatatctg acagcatggg
    15061 caggtcctaa gttagaaaag gacataccat ataatcttaa atctgaggca caaggtgcaa
    15121 ctaaaccttc aaatatggat actgcaccta ctcaatttaa tgtaacagat gttgttcgtc
    15181 ttaataaaga taaggaaact gtaaagaatg ctataatgca atatggttca gtgacatcag
    15241 gttatgcaca ttattcaaca tattttaata aagatgaaac agcatataac tgtacaaata
    15301 agagagctcc attaaatcac gctgtagcga tagtaggatg ggatgataat tattcaaaag
    15361 ataattttgc atctgatgta aaaccagaat caaatggagc atggttagta aaaagtagtt
    15421 ggggagagtt taattctatg aaaggattct tctggatttc ttatgaagat aaaactctac
    15481 taacagatac agataactat gcaatgaaat cagtatcaaa accagatagt gataaaaaaa
    15541 tgtaccaact tgaatatgct ggtcttagca agataatgtc aaataaagta acagcagcaa
    15601 atgtatttga ttttagcaga gactctgaaa aacttgattc tgttatgttt gaaacagact
    15661 ctgtaggagc aaaatatgaa gtatattatg caccagtggt aaatggagtt cctcaaaaca
    15721 attcaatgac aaaacttgca agtggaacag tatcatattc tggatacata aatgtaccta
    15781 ctaattctta cagcttacca aaaggtaaag gagcaatagt agtagttata gacaacacag
    15841 caaatcctaa tagagaaaaa tcaactttag catatgaaac taatatagat gcatattatt
    15901 tatatgaggc taaagcaaac ttaggtgaaa gctacatact tcaaaacaat aagtttgagg
    15961 atataaatac atatagtgaa ttttctcctt gtaactttgt tataaaagct ataacaaaaa
    16021 catcttctgg acaagctact tcaggagaat ctttaactgg agcagataga tatgaaacag
    16081 cagttaaagt tagtcaaaaa ggatggactt cttcacaaaa tgcagtatta gtaaatggag
    16141 atgcaatagt ggatgcttta acagctacac catttacagc agcaattgac tctccaattc
    16201 ttttgacagg aaaagataac ttagattcaa aaactaaggc agagttacaa agattaggaa
    16261 ctaaaaaagt ttatctaata ggtggagaaa attctttaag caagaatgta caaactcaac
    16321 ttagtaatat gggtatatca gtagaaagaa tttcaggtag tgatagatac aagaccagta
    16381 tatctctagc tcaaaagtta aatagtataa aatctgtttc acaagttgca gtggcaaatg
    16441 gtgtaaatgg acttgcagat gcaataagtg ttggtgcagc agctgctgat aacaatatgc
    16501 caataatact tactaatgaa aaaagtgagt tgcaaggtgc tgatgagttt ttaaattcat
    16561 ctaaaataac taagtcttat ataattggtg gaacagctac tttatcatca aatttagaaa
    16621 gtaagctttc aaatccaaca agacttgcag gcagtaatag aaatgaaact aatgctaaga
    16681 taatagataa attctaccct agctcagatt tgaaatatgc ttttgttgtt aaagatggtt
    16741 caaagagtca aggagacttg atagatggac tagcagtagg agcattgggt gctaaaactg
    16801 attcaccagt agttctagtt ggaaataagt tagatgaaag tcaaaaaaat gtacttaagt
    16861 ctaagaaaat agaaactcct attagagttg gtggaaatgg aaatgaaaat gcttttaatg
    16921 aactaaatac tcttttagga aaatagtgaa tggaaagata gtaaggatat acattttatt
    16981 attaaaaaat gttcaataga agtttataaa tataaaataa caaaaagggg tgtctcaaaa
    17041 tgaacttttt agttcatgag gcactctttt ttgttgtttt atatttttat catttaaata
    17101 atgaaaaata ggattgtcta tatttttaga tagttttctt attattgatg aaaaatgtaa
    17161 taattttaaa ctgtaaaata gtgtaaagtt attttataat ataaatatag taagatttta
    17221 aacaaaataa gggggaataa taatgaaagc accaaaaact attttaacaa tactgacaat
    17281 agcgcttact ttaagtagca tttctataat accatcatat gcacttacag aggaaaaatt
    17341 aataggtaat ggtagatatg aaactgctgt aaagataagt caaaaggcat acagttctag
    17401 tcctaatgta gtgctagtta atgacaattc attagctgat gcactttcag ctacaccatt
    17461 tgcaaaggct aaaggagcac caatactttt gacagaaagt gataagctag atgataggac
    17521 tgaaaaagag ataaaacgtc taggagctaa agatatttat ttgataggag gtactgctgt
    17581 acttaataaa gatatagaga acaagttaaa aagtaatgga cttaatgtag aaagaattaa
    17641 tggtaaggat agatatgaaa cttcactgat tttggctaat aagcttaagg atataaaaga
    17701 tattaaggaa gttgctgtag taaatggtga aaaaggattg agtgatgctg ttagcgttgg
    17761 ggcaccagca gctcaaaata agatgcctat aattttgtct agtcctaagg atggagtaga
    17821 agcatttgat aaatttataa gggatgagaa agttataaaa gcatatgtaa ttggaggtac
    17881 aaattctgtt tcaagagctg tagaaaagag tcttcctaat gcagaaagag tgagtgggaa
    17941 agatagaaat gagactaatg ctaaagttat agaaaagttt tacactgata caaatttaag
    18001 taatttatat gtaactaagg atggtagtaa aaatgagaat caactaatag actcgttagc
    18061 tgttggcgta ttggctgcaa aaaatgagtc tcctgttgtt ttggttggta ataaattaaa
    18121 cacaaaacaa agagatatac ttagtactaa aaaattaaat actataacac aggtaggtgg
    18181 aaatggaaat gaagaagctt ttgatgaaat taaaagtcta caagaaaaaa ctgtgtttga
    18241 agcaaaaact gttgaggaat taactgatat gataaatata gcaagtccta atgatattat
    18301 aaactttaaa ccaaaagaga atactgtaaa tgaagctttt agaatggtaa caaataaacc
    18361 aataactgtg aatataaagg gtgattgttc aaagactctt acagtagata tgcctaatgg
    18421 tgaagtgaat aactatgcta ctttggtaaa tgttatagtt agaaatattg gagaaggtgg
    18481 atttaataat catgatacaa tcactatatt gtcagttcgt gacaaaaatg gtagagttat
    18541 agaaaatact agaaattcag atatagatac gttgatgata ttagcttctg ctaatgatac
    18601 aaaattgatt aatgatggat atataggaaa acttatagat aattcatcta atagtgatat
    18661 aactaataat ggtactatag ataaaaaagt taatcaggtt gaagatttag aggctaaagt
    18721 agattcaatt gaaaaagcta tagattctat aagtcaaaaa gtcaataaaa tacaagatat
    18781 actagataag cttggatttc taaagaaatt tcttagctaa gaatatgtat atttaagtga
    18841 agtgtgtgtt gtaattgttc taaagttatg tagttaaaca ggtttatata caaatagatt
    18901 tatagataaa tatgtagttt agtatatatt tgaataagct ttggggaggt aacatgggga
    18961 ttggaattga atgtaacaaa aaaataaata aaagtattga caaaactaga ataaagaaaa
    19021 ataatct
//
LOCUS       DAMJVG010000080        19011 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.080, whole genome shotgun sequence.
ACCESSION   DAMJVG010000080 DAMJVG010000000
VERSION     DAMJVG010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19011)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19011)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19011
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.080"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     repeat_region   544..900
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=544..572
                     /rpt_unit_seq="gttttagattaactatatggaatgtaaat"
     gene            1062..1250
                     /locus_tag="PC512_002965"
     CDS             1062..1250
                     /locus_tag="PC512_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442697.1"
                     /translation="MKIITDSSRADYFKQRRQNKKTFSVLLDREKVEKIEEHLKKQNK
                     TKTIWLEEKINEELEKEE"
     gene            1369..2235
                     /locus_tag="PC512_002966"
     CDS             1369..2235
                     /locus_tag="PC512_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
                     /protein_id="HDF2442698.1"
                     /translation="MENLIVKEFNGSQIYTFMWKEKSCWIANQIVGLFDYADVSKTIQ
                     DCIKAEDFEIEQEYDVLKGNEFNDFVTTLNVVANNIISNKARSITIFYEDGLYGFLQY
                     TDKPIGVQFRKWLRREVLPSIRQTGAYITNNADPQALRDKANEIESLDTVNKTIEILT
                     PFLDNAGIDEKAKLLTAKTIYKKAGIELPLEIEEKEHFFDTVQIATKLNVYSKSNKPA
                     FHAIGEIIKKLDIQDNEKLVVLESKRGWSGSVNKYSQSVIDKVRNWIEENNRPTKIAG
                     EKKNYHVVYKIE"
     gene            2288..2443
                     /locus_tag="PC512_002967"
     CDS             2288..2443
                     /locus_tag="PC512_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442699.1"
                     /translation="MHENLLDIDRIELIKELGNIFEKMKNENPDEFYRFVSLVKEECR
                     KKEEKNK"
     gene            complement(2862..3074)
                     /locus_tag="PC512_002968"
     CDS             complement(2862..3074)
                     /locus_tag="PC512_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010249169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2442700.1"
                     /translation="MSIKFFKLIDLLNRRGITKEELRLKIGASSTTIAKLSSNKNVSL
                     DVIDKICKALNCQPGDIMEYEDDEKL"
     gene            3349..3693
                     /locus_tag="PC512_002969"
                     /pseudo
     CDS             3349..3693
                     /locus_tag="PC512_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012103644.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6N domain-containing protein"
     gene            3775..4128
                     /locus_tag="PC512_002970"
     CDS             3775..4128
                     /locus_tag="PC512_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442701.1"
                     /translation="MQFLVAKTFFKKAGVDIPLEIEEKEHFYDTKQIARKLGLYTMSN
                     KPAFMAVKQIIRKLDIKEDEMKTVLETNGNWTGTVTKYSNKVTEKVKVWLKENNNPIS
                     IKGDKKNYYILYKNN"
     gene            4161..4313
                     /locus_tag="PC512_002971"
     CDS             4161..4313
                     /locus_tag="PC512_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442702.1"
                     /translation="MYENLLDMDRIELIRELGSIFEKMKNENPDEFYRFVSLVKEECR
                     KKRERE"
     repeat_region   4607..5167
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=4607..4636
                     /rpt_unit_seq="gttgaagaataacatgagatgtttttaaat"
     gene            5290..5817
                     /locus_tag="PC512_002972"
     CDS             5290..5817
                     /locus_tag="PC512_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HDF2442703.1"
                     /translation="MREGKRRRGCLFWFILIILFSGVVGAIAGNSTNNESTEKQKEDL
                     TKYIGEEGSIGDLKLTVNSISKASEISVASGYLAYTPDSGKYGIINLTIKNQTKESQS
                     FMLNSFTLIGPDDSKYVPSLLIDVGNKYITMDTVNPNLDVTGNIAFEIPKDLLVSDCK
                     LKYSGSEQEFILKEK"
     gene            5956..6723
                     /locus_tag="PC512_002973"
     CDS             5956..6723
                     /locus_tag="PC512_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4428 domain-containing protein"
                     /protein_id="HDF2442704.1"
                     /translation="MGLFGKKKADICCICNTEIGVLNIEDGWICNSCFKEYCDALSMT
                     KAPKILRKLDIEKTISSTKKNNELQKIFNTTNNIENYIEFDEDNKKWFVSKKSINDKK
                     TPIIHSYEDIVEFELLENGETVTKGGIGRALAGGILFGEAGAIVGGITGKKTTRKVVD
                     TFKIKITINNIDNPIEYIELINKKTKTNSSAYEKAYKDAHKILSILSAITQSIKETDN
                     INTKSVADEILKYKNLLDMEAITQDEFNTKKKELLNL"
     gene            6789..9161
                     /locus_tag="PC512_002974"
     CDS             6789..9161
                     /locus_tag="PC512_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HDF2442705.1"
                     /translation="MATIQTSIKIFDGMTPAFRNMTNSINTTINSLERLQGRLNNPLN
                     AGNIQASQQSLNNIESILTRIEQKIGRNTNEQENFNNKIRQGSEAGSLLVSKLKSLAG
                     IYIGIRGIESITKAADTIASTKARLNLMNDGLQTTEQLNKMIYLSAQSARASYADTAA
                     QVSKLGILAGEAFGSSAEVVKFAELMNKSFVIGGTSASEASAAMYQLTQAMVAGKLQG
                     DEFRSIMENAPLLATKIAESMGKGKEALKDLSRTGAITADVVRNALFKASAEIEKKFE
                     SMPITFSQALTMMKNDAYMIFGQTLGKISGALQSVRFSEIVVSIRNVMIAISSNIYDT
                     LNIIKNILNSEFFSNLVQGFTFCVVVITKSLGSIVNTALNIVNIFAQNWSIIKPIVFG
                     VASVFILFRGVLLATKIATIGNVIANVAHAASSSLSALMTNIQAAALMRSNGATLSAT
                     IATWGLNAALLACPITWVVLGILAFVVVVFVAVAAVNKFAGTSLTALGVIVGAVFAAV
                     AAIQNVMIWLLNGCIAVNEGITNGWNQCVYLMKQAIAKGVIFIIEKMASLNDSVNNAG
                     NALGKAFVAGANIAIRGVNKLIDLLNKIPGVNIGKVGEATFTPVKADNSYIKQQIDSL
                     NKWVGDAPEKIKLDRMGYKDIGAEFQKGNALGTKWQNAITDKFKDTFDINKMLEDAKK
                     KLGLDDLWNKQNPLNNLGGFGGDLGKNVKDTAGNTAKMAKTMDKSQEDLKYLRDIAEQ
                     ETINRFTGVNIKIDMNNTNNISKDTDVDGIVNVLTEKLNDAMIVSAEGIV"
     gene            9177..9872
                     /locus_tag="PC512_002975"
     CDS             9177..9872
                     /locus_tag="PC512_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HDF2442706.1"
                     /translation="MAYDFYLDGVQLPIPPPKLEIKVTNKNKIVDLINTGEVNILKKE
                     GLSEISFEAEFTHNKLPFYRGAFRDVQFFLSKLELLKTDCKPFQFIVSRELGNKVLFN
                     TNIKVSLEEYAISEDAENGSDTKVAIKLKQYRDYSTKKLVLAPPKNETDRPNVKIEPK
                     RVDSVNATNTKTKTYTVKAGDSLWSICQKQLGNGSLYKKVYELNKSMMDKANKGKNLS
                     KYTIYKGQVLKLG"
     gene            9865..11820
                     /locus_tag="PC512_002976"
     CDS             9865..11820
                     /locus_tag="PC512_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HDF2442707.1"
                     /translation="MVDELVLANDRDVRLVIAHWEDFYEPAVIDGITWEIERRGTPSK
                     LEFTIVMDDILEFCEGNSVRLYYKGIGIFYGYIFQKKRDKENHIKIVAYDQLRYFKNK
                     DTYVYSNKTASELVKMLAKDFNLKYNVIEDTKYKISRIEENKTLFDMILTALDDTLRE
                     KKEMYVLYDDFGRITLKNVASMKLDTVMNNDVIEDFDYNSSIDSDTYTKIKLVRDNEE
                     SGKRDVYIAQDSAHMRSWGILQMFDTVDKNMSEAEIKQKCDILLKLYNKKTKSLSLKN
                     ALGDIRVRAGCLIPVFLDLGDIKLQNYMLVEKVKHTFENNSHFMDLTLVDGDEFASYS
                     SSSYSSGNANNKDEKKNGPAQSTTSKEDNDMINKLNKVFKNKLSNTGNIFVKYSNAYK
                     VNAALMAAISMHESARGTSNIANTKNNFFGMKKNGDYMSFSSVDEGIKRGISNLSRNY
                     IHIGRKTLESIRNKYSSSSDKEWVKCVGAFYKQITGSTYSSNNAGTGVGSNEEAEKNL
                     KDVTYQIQGNNQSSSTNNNSKADKLISVAKNKLGCKYVYGATGPNTFDCSGFTQWCYK
                     QIGIKIPRTVATQSKAGSAVDLKDRSKWKAGDLLCRVGGGSSNHVMMYIGNGQMIHSP
                     QTGDVVKIESVNSYRKGKAYTHVRRFI"
     gene            11834..12094
                     /locus_tag="PC512_002977"
     CDS             11834..12094
                     /locus_tag="PC512_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 domain-containing protein"
                     /protein_id="HDF2442708.1"
                     /translation="MSQDLLQIIKKAAMDAVETSNPMRVVFGTIESISPLRVKIEQKL
                     SIGEIFLIQTDTFKRYTDKKIGDKLVLIRMQGGQQYLILDRM"
     gene            12099..12518
                     /locus_tag="PC512_002978"
     CDS             12099..12518
                     /locus_tag="PC512_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HDF2442709.1"
                     /translation="MLPSDNLDYDIEDVSIINFDVRQEPSKTFKLHIEKSKIDGICDD
                     VEALKQTIFLILNTERYQHLIYSWNYGVELNDLIGEPISFVIPELERRIKEALIQDDR
                     VENVDNFEFENIKGKVQCKFSVHTKYGNIKAEKVVSV"
     gene            12519..13568
                     /locus_tag="PC512_002979"
     CDS             12519..13568
                     /locus_tag="PC512_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HDF2442710.1"
                     /translation="MFELMTFENIIKRMLDSVPNTLDKREGSIIYNALAPVAVELTET
                     YIAMDELLDQTFVDTASYYYLEKRCKERGITPLPATNTIAKGVFNIDIPLDSRFNLGE
                     YNYIAIERISEKTYKMKCETAGPIFELGKLIPIEYIDGLETAELTEILINGEDEESED
                     SLRQRYYDSLNSQSFGGNIQNYKDEVNKIQDVGGVKVYPVWDGGGTVKLVIINSNFKV
                     PSEDLVNLVQEEIDPIGHQGQGLGLAPIGHKVTVTGVVSTTINISAEITYKNGYTWEN
                     IKSIAEEAIDDYLNELNMSWEDEENLIVRISQIETRLLSIDGVLDITNTMINDVKSNL
                     TIDSNSIVVRGEVVG"
     gene            13561..14178
                     /locus_tag="PC512_002980"
     CDS             13561..14178
                     /locus_tag="PC512_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmfQ family protein"
                     /protein_id="HDF2442711.1"
                     /translation="MDKEINLINYLPQILQDKEEYIKVFNVENKEIKTLHEKLNDLSS
                     DQFLEDLTPSGIKRWEKIMSITPKSNESLEDRRFRIFSKYISKLPYSERFLRNWLDSI
                     VGEGNYELTINNATYNIHLESDARNQDWFEEVHSFVSSIKPCNMTLDYTRVLVSKDNY
                     MNFGITTLIGQEITIYPWSPPDIETYGEIDVLTGNGVGYQEITIF"
     gene            14190..15299
                     /locus_tag="PC512_002981"
     CDS             14190..15299
                     /locus_tag="PC512_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDF2442712.1"
                     /translation="MAIDKSYYTIITDVGKAKIANASVTGNKVGFVKIQLGDGGGSEY
                     TPTESQTALKNVVWEGNIGNTTTDETAPNCIILESLIPSSVGGFMIREIGYLDDENNL
                     IAISKYKECYKPSIEQGAVVDMKVKTVLIVSNVNNIELKIDPTIIFATLKDIQDLETK
                     IGTVNTKIDTTKTELTSNIETAKTELNTRIDTENEKQNIKIDQLIAGGSNVASTQTIT
                     IDDWVEDEENGFKATVTHSLLTQRIVVNIIDATTKENVVTNFKIIDDNSIEIRSEARS
                     ELNVYVINGNAETRFINATVDDNRVSEMTTYSSKKIEDSIGSIQLVDTSISITDANNR
                     FISNKLDGVLEEIMVEVNGQRAKGITIANDLIDMI"
     gene            15313..15951
                     /locus_tag="PC512_002982"
     CDS             15313..15951
                     /locus_tag="PC512_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442713.1"
                     /translation="MTEKLTENASLGELMAALENVQTDFQTGKNNISSALGSPFIGTD
                     KFGTTKTKIETLKNVLVETINSKNVSATSSETFTNLIEKVNWIFQSIEIFSLKNRIQA
                     TTLNTPSIVYNEVSSIKGTLRFTGELKASKMRADYATAKIEILCGNRKEYFYVTDDTP
                     SASSSFVRFTKDIIVENGMDIKVQILLTSVGAGNLDGSYAARAEIEKLTILR"
     gene            15961..16173
                     /locus_tag="PC512_002983"
     CDS             15961..16173
                     /locus_tag="PC512_002983"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442714.1"
                     /translation="MKKQVYYNSLDEKEKIISENSNLYVIEIYETLNENYLVLSSSPI
                     QDEKLSYEELENELLIMTNELQGGLL"
     gene            16173..16355
                     /locus_tag="PC512_002984"
     CDS             16173..16355
                     /locus_tag="PC512_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442715.1"
                     /translation="MNINNVVVRILAERILNGGLNPLKNREFQLDDVTNTEYRKAVED
                     YIIKNSGVVEGIEPTA"
     gene            16390..17625
                     /locus_tag="PC512_002985"
     CDS             16390..17625
                     /locus_tag="PC512_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442716.1"
                     /translation="MTFKELVNKVRNLVLEAKNVTIEDTENNFTSDNVEGALKEVFQN
                     GVNAKNNVVTALNSKGAEVTTSDTWEEIKNKIDIKEGRLDLRETILANSYSSYLVTNG
                     AIKYIEKYSGSLKALEYEEPYFYAIKGTHLIKINAIDESVIFDITLANANFSCICVTQ
                     EYLFISDNTKLYKINKLTGNEAQSIEGSYYKLCTYGEFIYGIYGDETSSILHKIRISD
                     MYIMLTKDMSSDRIYDFERGKFVCNNNGIYATTEHSNSSGLTECYLTKINFDFSVAKS
                     FRIGGYLYEKNIKFLNDFVFVSDSGRSIEVESGKKSGLAKYDANLNLITYGGSDRYEN
                     FEIYNGYIYTFNSLSSSPFIKINLNTLKEVNSYRTLINTNPQKGMFIINNIIFFIGGG
                     IHRNILSKKVYSDEKGEEL"
     gene            17622..17921
                     /locus_tag="PC512_002986"
     CDS             17622..17921
                     /locus_tag="PC512_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442717.1"
                     /translation="MIYLGNFMETDEQNIKYIGMIHYKPTLLSEEELKNGILIEKLPV
                     QQYVENKEAKLFINIDTKEVFYRYTDIKSSIEDKVNSTEQTIADLTFQLMSNGVI"
     gene            17923..18060
                     /locus_tag="PC512_002987"
     CDS             17923..18060
                     /locus_tag="PC512_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HDF2442718.1"
                     /translation="MNWYKIITDFYNNGNWTKEQVKTAVTKNKITASEYKEIVREDYI
                     A"
     gene            18122..18553
                     /locus_tag="PC512_002988"
     CDS             18122..18553
                     /locus_tag="PC512_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HDF2442719.1"
                     /translation="MNVTIVFLATNIFIKLVILAIAFDTLLGCLRAIKTHQFNSSFGI
                     NGGIRKVAMIACIFFLAVVDILTKFNFLFMLPQDWVDFLRLNHLGISEFFSILFILYE
                     SVSILKNMYLCGLPVPKRLKEKIGSLLDTMTDELNVKGGSK"
     gene            18553..19011
                     /locus_tag="PC512_002989"
                     /pseudo
     CDS             18553..19011
                     /locus_tag="PC512_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112536.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
BASE COUNT         7720 a         2026 c         3443 g         5822 t
ORIGIN      
        1 tttcattgtt tatataaaaa aaatggaaaa atatgtaata attatatgtt ataataattg
       61 tagcaaggat aataatcgaa agtgcgaagg gtgattattt tcatattaaa cgccaaattc
      121 caaataagga aggaggtgaa attatatgat aggtttttta ttaagcatac tagctggtgt
      181 tatatcagct tatatttatg acaaaataaa aaatcaccca gacgccaata agggtgattt
      241 aaaaaaataa ttctttaaat caattttgat ggaaatagct actcttgtat aaagtaaatt
      301 atttccttgc ttttattata ccacaaattg gtacagatat tcaaaaataa tatttttatg
      361 atataataaa aatataaata gttttgcagt gagcgatatt tgttacaaaa tatggtctaa
      421 cacttgaaat acaaggcatt gagggtgtgt gataaatgtt atcaattgca ctactcatgg
      481 ttcactgcaa atttgagaga gatgcgtatg tgtaggtatt ggaaatgcta agtttatttt
      541 ggggttttag attaactata tggaatgtaa attaaatata gcttcttctc cataactata
      601 agttgcatgt tttagattaa ctatatggaa tgtaaatcca aacgaatttg tattactaaa
      661 atcattccac aactgtttta gattaactat atggaatgta aattagcttg atagtatcca
      721 ccctccatgg cattgtttga gttttagatt aactatatgg aatgtaaatt cagaaacagg
      781 aacatcaaaa ggaggtttaa aatctggttt tagattaact atatggaatg taaattgctg
      841 tgatttcact aataaaacaa ttaataattg tgttatagat taactatgtg gagaaaaact
      901 aaataaacaa agaaagcact tacaaatatg taggtgcttt tgttttgctc aaattggtcg
      961 gttgagtgaa ataattagaa aaaattagta aaaactagta aaaactcttg aaaagtgtcg
     1021 cgatacaatg tataattata ttatcgcgat acagaaaaga ggtgaaaatt attactgata
     1081 gcagtagagc agattacttc aagcagagac gacagaataa gaaaactttt agtgttctac
     1141 tagatagaga gaaagtagaa aaaattgaag aacatttaaa aaagcagaac aagactaaaa
     1201 ctatttggct tgaagaaaag attaatgaag agttagaaaa agaggaataa aaaataagag
     1261 acgttctccc cgaccaaaga ttgaacatcc cttattgacg tatattatat acactaacta
     1321 tagtatacgt cattccttaa aaaaattcaa ttaaggagtg taatagttat ggaaaattta
     1381 atagtaaaag agtttaatgg aagtcaaatt tatactttta tgtggaaaga aaaatcttgt
     1441 tggatagcta atcaaatagt tggattattc gattatgctg atgtatctaa aacaatacag
     1501 gattgcataa aagcagaaga ctttgagatt gaacaagagt atgatgtatt gaaaggaaat
     1561 gaatttaatg attttgtaac tactttaaat gtagtcgcaa ataatataat tagtaataaa
     1621 gctagaagta taactatttt ttatgaagat ggtttgtatg gatttttaca atacacagat
     1681 aaaccaattg gtgtacagtt tagaaaatgg cttagacgag aagttttacc aagcataaga
     1741 caaactggtg catacataac aaataacgct gaccctcaag cactacgaga caaggcaaat
     1801 gaaatagaaa gtctagatac agttaacaag actatagaaa tactaacacc attcttagat
     1861 aatgctggaa tagatgaaaa agcaaagtta cttacagcaa agactatcta caaaaaggca
     1921 ggaatagagt tacctcttga aatagaagag aaggaacatt tctttgatac tgtacaaata
     1981 gcaactaagt taaatgttta ttctaagtct aataaacctg catttcatgc aataggtgaa
     2041 attattaaga agttagatat acaagataat gaaaagttag tagtactaga gagtaaaaga
     2101 ggttggagtg gaagtgttaa taagtattca cagagtgtaa tagataaagt gagaaattgg
     2161 atagaggaga ataatagacc tactaagatt gcaggtgaga agaagaatta tcatgtagtt
     2221 tataagattg agtaaattta taagattgta ttaaataatt tagtttagtt ttggggggat
     2281 taatacaatg catgagaatt tacttgatat agatagaata gaacttatca aagaacttgg
     2341 aaatatcttt gaaaaaatga aaaatgaaaa tccggatgaa ttttatagat ttgtaagttt
     2401 agtgaaagaa gagtgtagga aaaaagaaga gaaaaataaa taaatagaca aataaagcac
     2461 ttgaatattt tactgtttca agtgctttat gtagtaaaaa atgatataat ataggtagga
     2521 gttatattaa ctaagtggta tgtaaatgct gtatcctttg ccccttttgc tgcgtcactc
     2581 aaggttttta tattaacaat gtggtatgta aagtcgttta tcattgctag cctcgcattc
     2641 gtactggtca attttatatt aactaagtgg tatgtaaatc attcactaca aaatatatat
     2701 tctaatgtat cattcgtttt atattaacta tatggtatgt aaacaatata tatagcaaat
     2761 ctgttatatt aactatgaag ggttttatat taactatgtg gacttaaaat taaatagaaa
     2821 aaagaaagca cttacttaaa tagtaggtgc ttttgttttg cttataactt ttcatcatct
     2881 tcatattcca taatatcacc tggttggcag tttaaagctt tacatatttt atcaattaca
     2941 tcaagtgaaa catttttatt tgaagatagt ttggctattg tagtagaaga agctcctatt
     3001 ttgagtctta gttcttcttt agttatacct cttctgttta gtaagtcaat tagtttaaaa
     3061 aattttatag acatgttaat acctcctata tatttatata atactatata tatttattaa
     3121 agtaaagata tatttattaa aataaataaa aagtattgac attatttact aaataatgta
     3181 ttattagagt ataaagataa agaaatcttt ataaagataa agcaataagg gataaaataa
     3241 ggaatattct ctctcgtcaa agtttaaata ttccttatga catataacta atatgtaata
     3301 taattatatg tcattcctta aaaaaaatca attaaggagt gtatttttat gaacaattta
     3361 gtattaatta acaaccaaga gttgcaggtc aaggagttta ataatcaaag agtagttaca
     3421 tttaaagaaa ttgaccaagt acatgaaaga acagaaggta cagcaaagag aaatttctca
     3481 gagaatagaa aacattttat agagaacgaa gatttctttt ttgtaaaagc aagtgatttt
     3541 gaaaagtacg gaaatcgtac tttagaaatt cctaatcgtg gattaacttt aataactgaa
     3601 acaggctatt tgatgttagt aaaatctttt acagatgact tagcatggaa agtacaaaga
     3661 caattagtaa atagttattt tagagttaaa gaagaaataa aaacattaga agcagtaaat
     3721 gagtcaatta aattaataac tccatttttt gaagatttaa aaattgataa aagtatgcaa
     3781 tttcttgttg ctaaaacatt tttcaaaaaa gcaggagttg atattccact tgaaattgaa
     3841 gaaaaggaac atttttatga tacaaaacaa attgcaagaa agttaggact ttacacaatg
     3901 tctaataaac cagcatttat ggcagttaag caaattataa gaaagcttga tattaaagaa
     3961 gatgaaatga aaacagtatt agaaacgaat ggcaattgga ctggtactgt aacaaaatat
     4021 tctaataagg ttacagaaaa ggtcaaagtg tggttgaaag aaaataataa tcctatctca
     4081 atcaaaggag acaagaaaaa ctactatata ttgtataaaa ataattagat tttagtttag
     4141 ttttgagggg gattaataca atgtatgaga atttacttga tatggataga atagaactta
     4201 ttagagaact tggaagtatc tttgaaaaaa tgaaaaatga aaatccagat gaattttata
     4261 gatttgtaag tttagtgaaa gaagaatgta ggaaaaaaag agaaagagaa taaataatat
     4321 agataaagca cttataagta cataaaagtg ctttatcttc caaaatatgc tataattgta
     4381 gtatcaaata tatagggtga ttacgcatcc taagtgtgag attatcccaa gcaattggaa
     4441 ttgatactca caaagatgat tactaaataa agtaattatc accgtcccaa taaacattgg
     4501 gtaaaaacat ctgaaattta aaaacacttg ggataaattt gattaatgtt agtatttaca
     4561 atggttatgt tgttttattt tatttaagaa tgtgcatttt taagtggttg aagaataaca
     4621 tgagatgttt ttaaatagta ttagaaatac ttcgcttgtt tggaaatcat aagttgaaga
     4681 ataacatgag atgtttttaa attcatctaa aagtttagcc caagtttgaa ctgctatcgt
     4741 tgaagaataa catgagatgt ttttaaatct atctcttctt ttaccttcta taaaatttaa
     4801 ttgtgttgaa gaataacatg agatgttttt aaatctatta gttactttat agcttacata
     4861 gtaaatgcct gttgaagaat aacatgagat gtttttaaat actgtttctc tgttcgaagt
     4921 atgtgctaca tctccaagtt gaagaataac atgagatgtt tttaaatgaa agccacgctt
     4981 gcgcattaga ctgtttgaag ttggttgaag aataacatga gatgttttta aattgaataa
     5041 attcttttgt atttttatca aaatacggct cgttgaagaa taacatgaga tgtttttaaa
     5101 tatgtgttga agcagaagct tttgagaatg gtttagagtt gaagaataac atgggatgta
     5161 aaaataaata tttatataaa acacttactt aaatagtagg tgttttttaa ttgaaaggat
     5221 gtgattataa tgtaaaaatt ttgaagatat agtataatat tcttataaaa tataatttag
     5281 ggggatatta tgagagaagg aaagagaaga agaggatgtc tattttggtt tattcttatt
     5341 attttatttt ctggagttgt tggagcaata gcagggaaca gtactaataa tgaaagcact
     5401 gaaaaacaga aagaggattt aactaaatat attggtgaag aaggtagtat aggagattta
     5461 aaattaactg ttaatagcat ttcaaaagct agtgaaatat cagtagcatc tggttattta
     5521 gcatacactc cagatagtgg caaatatggt attataaatt taacaataaa aaatcaaact
     5581 aaggaaagcc aatcttttat gctaaattca ttcacattaa taggaccaga tgattcaaaa
     5641 tatgttccat ctttattgat tgatgtagga aataaatata taactatgga tactgtaaat
     5701 cctaatttag atgtaacagg taatattgca tttgaaattc ctaaggattt actagtttct
     5761 gattgtaaac taaaatatag tggttcagag caagaattta tattaaaaga aaaataatat
     5821 atagatttaa aaatatgaag catttacttt aaataagtaa gtgctttttt aattgaaagg
     5881 aggtgataat aatgtaaaaa ttttacttat atagtataat tacattataa aattattgta
     5941 ctggggggga atcttatggg gttatttgga aagaaaaaag cagatatatg ttgtatttgt
     6001 aatactgaga taggagtact gaatattgaa gatggttgga tatgcaattc ttgttttaaa
     6061 gaatattgtg atgcactttc tatgactaaa gcacctaaaa ttttaagaaa attagatatt
     6121 gaaaagacta tatcatcaac taaaaaaaat aatgaacttc aaaaaatatt taatacaact
     6181 aataatatag aaaactatat agaatttgat gaagataata aaaaatggtt tgtgtctaaa
     6241 aaaagtataa acgataaaaa aactcctatc attcattctt atgaagatat cgtggaattt
     6301 gaacttcttg aaaatggtga aactgtaact aaaggaggaa taggaagagc tttagcggga
     6361 ggaattttat ttggagaagc aggagctata gttggaggga taacaggtaa aaaaacaaca
     6421 agaaaagttg ttgatacatt taaaattaaa ataacaatta ataatattga taatcctatt
     6481 gagtatatcg aattaattaa taaaaaaaca aaaactaatt ctagtgctta tgagaaagct
     6541 tacaaagatg cccataaaat tttatcaata ttatctgcta ttacacaaag cattaaagag
     6601 acagacaata taaatactaa atctgtagca gatgagatat taaaatataa gaatcttttg
     6661 gatatggaag ctattacaca agatgaattt aatactaaga aaaaagaatt attgaatttg
     6721 taatataata aacacttact aatgtaggtg tttttttata tggaaattta tgaaaggaga
     6781 gtgaggaaat ggctacaata caaacttcaa taaagatttt cgacggaatg acaccagcat
     6841 ttcgtaatat gactaattct attaatacaa caattaatag tttagagaga ttgcaaggca
     6901 gattgaataa tccactcaat gcaggtaata tacaagcttc tcaacaaagt ttgaataaca
     6961 tagaaagtat tctcacaagg atagaacaga aaattggaag aaatacaaat gaacaagaaa
     7021 actttaataa taaaataaga caaggaagtg aagcaggctc tctattagta tctaaactca
     7081 aaagtttggc tggcatatat attggaataa gaggtataga aagtattaca aaagcagcag
     7141 atacaattgc aagtacaaaa gcacgtttaa atttaatgaa tgatggatta cagacaacag
     7201 aacaacttaa taagatgatt tatttatctg ctcaaagtgc tagggcttct tatgcagaca
     7261 cagcagcaca agtatctaag ttaggaatac ttgcaggaga agcttttgga agtagtgcag
     7321 aagttgtaaa atttgcagag ttaatgaata agagtttcgt aattggagga acatcagcat
     7381 cagaagctag tgcagcaatg tatcagttaa cgcaagctat ggtagcagga aaattgcaag
     7441 gtgatgaatt taggtctatc atggaaaatg caccacttct agctactaaa atagctgaat
     7501 ctatgggtaa gggtaaagaa gcactaaaag atttgtctcg gacaggtgct attacagcag
     7561 atgtagtgag aaatgctttg tttaaagcaa gtgctgaaat agaaaagaaa ttcgaaagta
     7621 tgccaataac ttttagtcaa gcacttacta tgatgaaaaa tgatgcttat atgatatttg
     7681 gtcagacatt aggaaagata agtggagcat tgcaaagcgt tagatttagt gaaattgttg
     7741 tatctataag aaatgttatg attgcaatat cttcaaacat ttacgataca ttaaatatta
     7801 taaaaaatat tttaaatagt gaattctttt caaacttagt acaaggattt acattttgtg
     7861 tggtagtaat aactaaaagc ttaggttcta ttgtaaatac tgcattaaat atagttaata
     7921 tatttgcaca aaattggagt ataataaaac ctattgtatt tggtgtagct tctgttttta
     7981 tattgtttag aggggttttg ctagcgacta aaatagctac aataggtaac gtaattgcga
     8041 atgttgctca cgctgcttcc tcttcactat cagcacttat gactaatata caagcagcag
     8101 cactgatgcg ttcgaatgga gctactttat cagcaacaat agccacttgg ggtttaaatg
     8161 cagctttatt agcttgtcca atcacatggg tagtattagg tattctagca tttgtagtag
     8221 tagtttttgt tgcagtagca gcagtaaaca aattcgcagg tacaagttta actgccttag
     8281 gagtaattgt gggtgctgta tttgcagcag tggcagcaat acaaaatgtt atgatatggc
     8341 tactgaatgg ctgtatagct gtaaatgaag gcattacaaa tggttggaat caatgtgtat
     8401 atcttatgaa acaagctatt gcaaaaggtg taatctttat aatcgagaaa atggcatctc
     8461 taaatgattc tgtaaataat gcaggaaacg cacttggtaa ggcttttgtg gctggggcga
     8521 atatagcaat cagaggagta aataagctta ttgatttact aaacaaaatt cctggagtaa
     8581 atattgggaa agttggagaa gcaacattta cgcctgtcaa ggcagataat agttacatca
     8641 aacaacagat tgacagttta aataaatggg taggagatgc accagaaaaa ataaaattgg
     8701 atagaatggg atataaagat attggagcag aatttcaaaa aggaaatgca cttggaacta
     8761 aatggcaaaa tgctataact gataaattta aagatacttt tgacattaat aagatgctag
     8821 aagatgcaaa gaaaaaatta ggattagacg atttgtggaa taaacaaaat cctttaaaca
     8881 accttggtgg atttggtgga gatttaggaa aaaatgtaaa agacacagca ggaaacacag
     8941 ccaaaatggc taaaacaatg gataaaagtc aagaagacct taaatactta agagacattg
     9001 cagaacaaga aacaataaac agattcacag gagtaaacat aaaaattgat atgaacaata
     9061 ctaacaatat aagtaaagac acggatgtgg atggtatagt aaatgtttta acagaaaaac
     9121 tgaatgatgc tatgattgta tcagcagaag gaatagttta gaaaggaggg atataaatgg
     9181 cttatgactt ttatttagat ggagtacaat taccaatacc tccgccaaag ttagagatta
     9241 aagttacaaa taaaaacaag atagttgatt tgataaatac tggagaagta aacatactaa
     9301 aaaaagaagg attatctgaa ataagttttg aagcagaatt tacacataat aagttgccat
     9361 tctatcgtgg agcttttagg gatgttcaat tctttttaag taaactggaa ctattaaaaa
     9421 ctgattgtaa gccatttcaa tttattgtat cgagggaatt aggtaataaa gtactattta
     9481 acactaatat aaaagtatct cttgaagagt atgctatttc agaagatgca gaaaatggtt
     9541 cagatacaaa agttgcaata aagttaaagc aatatagaga ttactcaact aaaaagttag
     9601 ttcttgcccc tcctaaaaat gagactgata gacctaatgt aaagatagag ccaaaacgag
     9661 ttgattcagt caatgccaca aacactaaaa ctaaaacata tacagtaaaa gcaggggata
     9721 gcctttggtc aatttgtcag aaacaacttg gtaatggttc attatataag aaagtatacg
     9781 aactaaataa atctatgatg gataaggcaa ataagggcaa aaacttaagt aaatacacta
     9841 tttataaagg gcaggtgtta aaacttggtt gatgaattag tgttagcaaa tgatagagat
     9901 gtaaggttag taatagctca ttgggaagat ttctacgaac ctgctgtcat tgatggtatc
     9961 acatgggaga tagaaagaag aggaacacct tctaagttag aatttacaat agttatggat
    10021 gatatattag agttttgcga aggaaattct gtaaggctgt attataaagg aataggtatc
    10081 ttctatggat atatatttca gaagaaaaga gataaagaaa atcacattaa aattgttgct
    10141 tacgaccagc taagatattt taagaataaa gatacttatg tatatagtaa taaaactgca
    10201 agtgaacttg taaaaatgtt ggctaaagat tttaatttaa aatacaatgt catagaagat
    10261 actaagtata aaatatctag gatagaagaa aataaaacac tctttgacat gatactaaca
    10321 gcactagatg atactctaag agagaaaaaa gaaatgtatg ttttatatga tgattttgga
    10381 agaataacat taaagaatgt tgcatcaatg aaattagata ctgttatgaa taatgatgtc
    10441 atagaggact ttgactacaa ttcttctatt gatagtgata cttacacaaa gattaaactt
    10501 gtaagagaca acgaggagtc aggaaaaagg gatgtatata ttgctcaaga ctcagctcac
    10561 atgagaagtt ggggaatact tcaaatgttt gatacagtag ataaaaacat gagtgaagca
    10621 gaaataaagc aaaagtgtga tatacttcta aaactatata ataagaaaac taagtcatta
    10681 agtttaaaaa atgcacttgg tgatattaga gtaagagcag gttgtttaat acctgttttt
    10741 ttagatttgg gagatattaa acttcaaaat tatatgttag ttgagaaagt aaaacataca
    10801 tttgaaaata attcacattt catggatttg accttggttg atggagacga atttgcttct
    10861 tattcctctt caagctacag tagtggaaat gcaaataata aagatgaaaa gaaaaatggt
    10921 cctgcacaaa gtactacaag taaagaagac aatgatatga taaataaatt aaataaagta
    10981 tttaaaaata agttatcaaa tacaggaaat atatttgtta aatattctaa tgcttacaaa
    11041 gtcaatgcag ctttaatggc tgctatatct atgcacgaat cagctagagg gacttcaaat
    11101 attgcaaata ctaaaaataa tttctttgga atgaaaaaaa atggagatta catgagtttt
    11161 tctagtgtag acgaaggaat aaaaagaggt ataagtaatt tatcaagaaa ctatatccat
    11221 ataggacgaa aaactttaga aagcatcaga aataaatatt cttctagttc agacaaagaa
    11281 tgggtaaaat gtgtaggtgc attttataag caaataacag gaagtactta tagttctaat
    11341 aatgcaggta caggagttgg aagcaacgag gaagcagaaa agaatttaaa agatgtaact
    11401 tatcaaattc aaggcaacaa ccaaagcagt agtacaaata acaattctaa agcagataaa
    11461 ctaattagtg tagcaaaaaa taaattaggt tgtaaatatg tgtatggagc tacaggacct
    11521 aatacttttg attgcagtgg atttactcaa tggtgttata aacaaatagg tataaaaatt
    11581 cctaggactg ttgcaacgca aagtaaggca ggcagtgcag tagatttaaa agatagaagc
    11641 aagtggaaag caggagactt attatgtaga gttggtggag gtagtagtaa tcacgtaatg
    11701 atgtatattg gaaatggtca aatgattcat tcaccacaaa caggagatgt ggtaaaaata
    11761 gagtctgtta attcttatag aaaaggaaaa gcatacacac atgtgagaag atttatataa
    11821 gtgaggtggc aatatgagcc aagatttatt acagataata aaaaaagctg caatggatgc
    11881 agtagaaaca agcaacccaa tgagggttgt atttggaaca atagaaagta ttagtcctct
    11941 aagagttaag atagaacaaa aactatctat tggtgaaatt tttctaatac aaacagatac
    12001 atttaaaaga tatacagata aaaaaatagg agataaatta gtcttaattc gtatgcaagg
    12061 agggcaacaa tacttgattt tagataggat gtgataaagt gttaccaagt gataatttag
    12121 attatgatat tgaagatgta tcaataatta attttgatgt aagacaagag ccaagtaaga
    12181 catttaaact tcatatagaa aagtctaaga ttgatggtat ttgtgatgat gtagaagcat
    12241 taaaacagac catctttttg attttaaaca cagagagata ccaacatcta atatatagtt
    12301 ggaattatgg agtcgagttg aacgacctta ttggagagcc tatatccttt gtaataccag
    12361 agttagagag aagaatcaaa gaagcactaa ttcaagatga tagggttgaa aatgtagata
    12421 attttgagtt tgaaaatata aagggtaaag tacaatgtaa attttcagtt catacaaaat
    12481 atggaaatat aaaagcagag aaggtggtga gtgtataatt gtttgagtta atgacatttg
    12541 aaaatataat taaaagaatg ttagatagtg tacctaacac acttgataag agagaaggtt
    12601 ctataatata caatgccttg gcaccagttg cagtggagct tacagaaaca tatattgcta
    12661 tggatgaatt actagaccaa acattcgtag atactgctag ttattactat ttagagaaga
    12721 gatgtaaaga gcgaggaatt acacctttac cagccactaa tacaattgct aaaggagttt
    12781 ttaacataga tattccactt gattctaggt ttaatctagg agaatacaat tatattgcaa
    12841 ttgagagaat atctgaaaaa acatataaaa tgaaatgtga aactgctgga cctatatttg
    12901 agttaggaaa actaatacct attgaatata tagatggtct tgaaactgct gaactaactg
    12961 aaatcttgat aaatggagag gatgaagagt cagaagatag tttaagacaa agatattatg
    13021 atagcctaaa ttcacagagc tttggtggga atatacaaaa ctataaagat gaagttaaca
    13081 aaatacaaga tgttggagga gttaaggttt atcctgtgtg ggacggtgga ggaactgtta
    13141 agttagtaat aattaactct aatttcaaag taccatcaga ggatttagtt aatttagtgc
    13201 aagaagaaat tgacccaatt ggacatcaag gacaaggctt aggattagca ccaatagggc
    13261 ataaagttac tgttacaggt gttgtaagta caactataaa tatatcagca gagataacat
    13321 acaaaaatgg ctacacttgg gagaatataa aatcaattgc agaagaagca atagacgact
    13381 atttaaatga acttaacatg agttgggaag atgaagaaaa cttaatagtc cgtatatctc
    13441 aaattgaaac tagattactt agtatagatg gagtgttaga tattacaaac acaatgataa
    13501 atgatgttaa atctaatcta acaatagata gtaacagtat agtagtgaga ggtgaggtag
    13561 ttggataaag agattaatct aataaattac ttaccacaaa ttctacaaga taaagaagaa
    13621 tatataaaag tatttaatgt agaaaacaaa gaaataaaaa cactacatga aaaattaaat
    13681 gacctatcaa gtgaccagtt tttagaggat ttaactccaa gtggtataaa aagatgggaa
    13741 aagataatgt ctataactcc taaaagtaat gagagtttag aagatagaag gtttaggatt
    13801 tttagtaaat atataagtaa actaccttac tcagagagat ttttaaggaa ctggctagat
    13861 agtatagttg gagaaggcaa ttatgaatta actattaata atgctactta taatatacat
    13921 cttgaaagtg atgctagaaa tcaagattgg tttgaggagg ttcattcttt tgtaagtagt
    13981 attaaacctt gcaacatgac tttagattac actagagtgc ttgtaagtaa agacaattat
    14041 atgaattttg gtataacaac cctaataggt caagaaataa ctatataccc ttggagtcca
    14101 ccagatatag aaacttatgg agaaattgat gtattaactg gcaatggagt tggataccaa
    14161 gagataacaa tattttagga ggtgatatat tggctataga taaaagttat tacactataa
    14221 ttacagatgt agggaaagca aagatagcaa atgcaagtgt cacaggtaat aaagtgggat
    14281 ttgtaaaaat tcaacttggt gatggaggag ggagtgaata tactccaact gagagtcaga
    14341 cagctctcaa aaacgtggta tgggaaggca atattggaaa tacaactaca gatgaaactg
    14401 caccaaattg tataatatta gagagtttaa taccatcaag tgtaggcgga tttatgataa
    14461 gagaaatagg atatttagat gatgaaaata atttaattgc catttctaaa tacaaagagt
    14521 gttataaacc ttctatagaa caaggtgcag tggtagacat gaaggttaaa actgtgctta
    14581 ttgtatctaa tgtaaataat atagaactta aaattgaccc aacaataatc tttgcaacac
    14641 tcaaagatat acaagactta gaaactaaaa taggtactgt taatactaaa attgatacaa
    14701 ctaaaacaga attaacaagc aacatagaaa ctgctaaaac agagttaaat actagaattg
    14761 acacagaaaa tgagaagcaa aatattaaaa ttgaccaact tattgcaggt ggctctaatg
    14821 tggcatctac tcaaacaata acaattgacg attgggttga ggatgaagaa aatggattca
    14881 aagcaactgt aacacatagt ttattaacac agagaatagt tgtaaatatt atagatgcta
    14941 ctacaaaaga aaatgtagtt acaaacttta aaattataga tgataattct atagaaatta
    15001 gaagtgaagc aaggtcagaa ttaaatgttt atgtgataaa tggaaatgca gaaactcgtt
    15061 ttattaatgc aactgtggat gataacagag tatctgaaat gactacttat tcgtctaaga
    15121 aaatagagga ttctattggc agtatacaac ttgtagatac cagtataagt atcacagatg
    15181 ctaataatag atttataagt aataaactag atggagtatt agaggaaata atggtagagg
    15241 taaatgggca aagagctaaa ggaattacta tagcaaatga tttaatagat atgatataag
    15301 cgaggtgaaa atatgacaga aaaattaact gaaaatgcta gtttagggga acttatggca
    15361 gcattagaaa atgtacaaac tgattttcaa actggtaaaa ataatatatc tagtgcattg
    15421 ggtagtcctt ttattggaac agataaattt ggtacaacta aaacaaaaat agaaacatta
    15481 aaaaatgtat tagtggagac gattaattct aaaaatgttt cagcaacatc atctgaaaca
    15541 tttactaatt tgattgaaaa agttaactgg atttttcaat caatagaaat tttttcttta
    15601 aaaaatagaa ttcaagctac aactttaaac actcctagca tcgtttacaa tgaagtatct
    15661 agtataaaag gcacattaag attcacaggc gaacttaaag cgtctaaaat gcgtgctgat
    15721 tatgcaacag caaaaataga gatactatgt ggaaaccgaa aagaatactt ttatgttact
    15781 gacgatactc ctagtgcatc ttcttctttt gtaagattta caaaagatat tattgttgag
    15841 aatggcatgg atataaaagt acaaatatta ttaacatctg taggagcagg aaatttagat
    15901 ggttcatatg cagctcgtgc agaaatagaa aaattaacaa tattaaggta ggaataaatt
    15961 atgaaaaaac aagtatatta taattcttta gatgaaaaag aaaaaataat tagtgaaaac
    16021 tctaatttat atgttataga aatatatgaa actttaaatg aaaattattt agtgttatca
    16081 agtagtccaa tacaagatga aaaacttagt tatgaagaat tagaaaatga attattaatt
    16141 atgactaatg aattacaagg aggattgtta taatgaatat aaataatgtt gtggtaagaa
    16201 tattagcaga aagaatatta aatggagggt taaacccttt gaaaaataga gagtttcaac
    16261 ttgatgatgt aactaacaca gaatacagaa aagcagtaga ggattatatt ataaaaaata
    16321 gtggagtagt agaaggaata gaaccaacag cgtagtaggt tctttttttt attgaaagaa
    16381 ggtgactaaa tgacttttaa agagttagtt aataaagtta gaaatcttgt attagaagca
    16441 aagaatgtaa ctatagaaga tacagagaat aactttacaa gtgataatgt agaaggagca
    16501 ttaaaagagg tttttcaaaa tggagttaat gctaaaaata atgtagtaac agcattaaac
    16561 tccaagggag cagaggttac tacaagcgat acatgggaag aaataaagaa taaaattgat
    16621 ataaaagagg ggagattaga tttaagagaa acaatacttg caaatagtta ttcttcatat
    16681 ttggttacaa atggtgctat aaaatatatt gaaaaatata gtgggagttt aaaagcatta
    16741 gaatatgaag aaccctattt ttatgcaatt aaaggtacac atttaattaa aattaatgca
    16801 attgatgaat ctgtaatttt tgatattact ttagccaatg ctaacttctc atgtatctgt
    16861 gttactcaag agtatttatt tatatctgac aatactaaat tatataaaat aaataagtta
    16921 acaggaaatg aagcacagtc aatagaaggt tcttattata agctatgtac ttatggggaa
    16981 tttatttatg gaatatatgg agatgagact tcttcaatac ttcacaaaat aagaatatcg
    17041 gatatgtata taatgctaac taaagatatg tcctctgata gaatttatga ctttgaaaga
    17101 ggcaaatttg tatgtaataa taatggtatt tatgctacaa cagaacactc aaattcaagt
    17161 ggtcttacag aatgttacct aactaaaata aattttgatt ttagtgttgc gaaaagtttt
    17221 agaattggag gatatttata tgaaaaaaac attaagtttt taaatgattt tgtttttgta
    17281 tctgatagtg gcagaagcat agaagttgag agtggtaaaa aaagtggatt agcaaaatat
    17341 gatgcaaatc taaatttgat tacttatggt gggtcagata gatatgaaaa ttttgaaata
    17401 tataatggat atatatatac atttaattca ctttctagta gcccatttat aaaaataaat
    17461 ttaaatactc ttaaagaagt taatagctac cgaacgctca ttaacacaaa tcctcaaaaa
    17521 ggtatgttta taataaacaa tataattttt tttattggtg gtggcattca cagaaatata
    17581 ttatcaaaaa aggtttattc agatgaaaaa ggagaggaat tatgatttat ttaggaaatt
    17641 ttatggagac agatgaacaa aatataaaat atattgggat gatacactat aaaccaactt
    17701 tactatcaga agaagagtta aaaaatggaa ttttaattga gaaattgcca gtacaacaat
    17761 atgtagaaaa taaagaagca aagttattta taaatataga tactaaagag gttttctata
    17821 gatatacaga tattaaaagt agcatagaag ataaagtaaa ttctacagaa caaacaatag
    17881 cagatttaac atttcaatta atgagtaatg gggtgatata gtatgaattg gtataagata
    17941 ataacagatt tctataataa tggtaattgg actaaagagc aagttaaaac agcggttaca
    18001 aagaataaga taacagcaag tgaatataaa gaaattgtaa gagaggacta tatagcgtag
    18061 ttcttttaaa tagacttaga taatttctaa gtcttatttt aatgcagaat aaggaggaaa
    18121 tatgaacgta acaatagttt ttttagcaac aaatatattt ataaaattag taatattagc
    18181 aatagcattt gatacactgt taggttgctt aagagcaata aaaacacatc agtttaatag
    18241 ctcttttgga ataaatggag gaataagaaa agtagcaatg atagcatgta tattttttct
    18301 agcagtagtt gacattctta caaagtttaa ctttttattt atgttgccac aagattgggt
    18361 tgattttttg cgattaaatc atcttggaat atctgaattt ttctctattt tatttattct
    18421 atatgaaagt gtaagtatat taaaaaatat gtacttatgt ggattaccag ttcctaaacg
    18481 attaaaagag aaaataggta gtttattaga tactatgaca gatgaattaa atgttaaagg
    18541 aggtagtaaa taatgaaaat atgtataaca gtaggacaca gtattttaaa aagtggagca
    18601 tgtacttctg ctgatggagt agttaacgag tatcaataca acaaatctct tgcaccagta
    18661 ttagcagata catttagaaa agaagggcat aaggtagata atatgcccag aaaagcagtt
    18721 taaaactaag aatgaagaaa agtcttataa aatacctaga gttaatagtg gaggatatga
    18781 tttacttata gagttacatt taaatgcaag taacggtcaa ggtaaaggtt cagaagtcct
    18841 atattatagt aataaaggct tagagtatgc aactagaata tgtgataaac taggtacagt
    18901 atttaaaaat agaggtgcta aattagataa aagattatat atcttaaata gttcaaagcc
    18961 tacagcagta ttaattgaaa gtttcttctg tgataataaa gaagattatg a
//
LOCUS       DAMJVG010000081        18835 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.081, whole genome shotgun sequence.
ACCESSION   DAMJVG010000081 DAMJVG010000000
VERSION     DAMJVG010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18835)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18835)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18835
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.081"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(305..697)
                     /locus_tag="PC512_002990"
     CDS             complement(305..697)
                     /locus_tag="PC512_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF2442720.1"
                     /translation="MAALKSFEKPLTPEEEIEYLTKFKIENDKSAKDTLIERNMRLVA
                     YIAKKYNNSTEDQDDLISIGTIGLIKAIETYNIDKGTRLATYASRCIENEILMNIRSN
                     KKNKTQVSLQDPIGTDKEGNEINTTLYM"
     gene            1264..1626
                     /locus_tag="PC512_002991"
     CDS             1264..1626
                     /locus_tag="PC512_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442721.1"
                     /translation="MKIRKSGFISIECIISIAILYVAVYLVSTSLYNCYSFISRNISD
                     REMLSTAKKYIEDEKYRIQNSKYELIEDKIEKNYINGYEINSRIEQILDYYQCYEINI
                     EIKNEFKKLRFNSYVTRK"
     gene            1610..2317
                     /locus_tag="PC512_002992"
     CDS             1610..2317
                     /locus_tag="PC512_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442722.1"
                     /translation="MLLENKGSILIITLIIFSIISTVCIMCIGLIYTHNNMFELGYKD
                     IQLKEISLSGIEISVSNVLSCVEEAIDISNNEDEFREYFLGNNMIECIKKIKDTSYSS
                     LEELSLKVENNTIYDRGDFFEFDIESNVREKEFLKAIKVRVKIKNPWIGIDIEDYMDK
                     SNNNKIDDKTFNNYKASENNEIINQFKNESENIRNQEVVEFTEEDEEELKQNIIENIK
                     KNFDEKNLVQVYKYRGV"
     gene            2337..2756
                     /locus_tag="PC512_002993"
     CDS             2337..2756
                     /locus_tag="PC512_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442723.1"
                     /translation="MTVIELIVSISIILLIVTLSFPKDNLENHKINLFARQLCSDIRY
                     VRRINMFSNYNTYIYYINQGKHEGYVLRKDGKNIKSIMLPKNAKIARSIEIIKFKSDG
                     SPQKASTIEVYNNRLRKTITITPVSGRVLLKEGKYET"
     gene            2746..3270
                     /locus_tag="PC512_002994"
     CDS             2746..3270
                     /locus_tag="PC512_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442724.1"
                     /translation="MKHKYGYLLLESVVSLSSMVIIILVLYSIFLSTINLKLKVEDKI
                     ELQQQSLEIIKSMEGIISNSMGIMNVSNYEETFKKTTSIKCRYLDENNNEEGISNKEI
                     ILNERRNKLFVNSLNGESSQAGGYEIGDYVDEMYVSITNNGQYVNIKLKLSKCSQKYE
                     TDFKIKVWNFSESI"
     gene            3582..4139
                     /gene="efp"
                     /locus_tag="PC512_002995"
     CDS             3582..4139
                     /gene="efp"
                     /locus_tag="PC512_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HDF2442725.1"
                     /translation="MVSAGDFRKGVTFEKDGQPCLVVDFQHVKPGKGAAFVRTKYKNL
                     KTGAIREESFNPSEKFPKAVIDTRQMQYLYNDGELYYFMDQENFEQIPLNYEQVEDAI
                     KFLKENEVATIRFYQGQPFQVEAPNFAELEVTDTEPGIKGDTASNVTKAATVETGAVV
                     QVPLFINTGDKVKIDTRTGEYLSRV"
     gene            4231..4686
                     /locus_tag="PC512_002996"
     CDS             4231..4686
                     /locus_tag="PC512_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HDF2442726.1"
                     /translation="MKHLYEEVAYLKGLAEGLEISAESKEGKMIHKIVDALEVFADAI
                     VTLDEEQEELQDFVESIDEDLADLEEDIADMEEDLYEEDDDEDDEDFSYIEMECPNCG
                     ELVEIDEDLLYDDEVDVVCPDCKAVILSSEDDCDDDCTCGGCSSCDDRE"
     gene            4849..5559
                     /locus_tag="PC512_002997"
     CDS             4849..5559
                     /locus_tag="PC512_002997"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HDF2442727.1"
                     /translation="MKISKKLLDNIQRFENVINYKFKNKEYILEALTHSSYSNENKKY
                     NFNERLEFLGDSVLGIVISDYLFNEEANLPEGELTKLRANIVCEDSLSEVANDINLGI
                     HMLLGRGEEATGGRHRTSILADAFEAVIAAIYLDGGFESARQFILHHMENIIYDSRKG
                     NIFRDYKTHLQEVLQGNGENNIWYRLIEEKGPDHNKRFVMEVGINDDVLGIGEGKSKK
                     EAEQLAAKIALKKKLWEK"
     gene            5613..6683
                     /locus_tag="PC512_002998"
     CDS             5613..6683
                     /locus_tag="PC512_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF2442728.1"
                     /translation="MKKRIIPIFVPHKGCPHDCIFCNQKKITGVSTDVTSEDARNIIE
                     ECLETIDKDADVEIAFFGGSFTAIDIDIQKSLLSVAKEYVEKGLVKDIRMSTRPDCID
                     EDILSMLKEYKTSIIELGVQSLDEKVLLDSIRGHQSEIVYKSSKMIKNSGIKLGLQMM
                     IGLPADTEEKCIFTAKKFVELKPDCVRVYPTLVVKDTGLEKLMEQNKYNPFTLEESVN
                     IVKKVLVLFYVNNINVIRVGLQATDDIQIGKAVLAGPYHPAFRELVEADMIKDYLEFV
                     ILQNKNIKQMLVKSNKKNISKIIGNKKTNVKYMEEKFGVLLKTQESDLDINQLEIVLD
                     GKSLISANMRDIHRKLYDIYDL"
     gene            6711..10265
                     /gene="smc"
                     /locus_tag="PC512_002999"
     CDS             6711..10265
                     /gene="smc"
                     /locus_tag="PC512_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HDF2442729.1"
                     /translation="MYLKRLELKGFKSFPVKTDIIFKEGITAIVGPNGSGKSNISDAV
                     RWVLGEQSIKSLRGDKLEDVIFAGTDTKKPMNYCEVALTIDNSENQLELDFTEVTIRR
                     RAYRNGESEFFLNNKSCRLKDIKEVFLDTGIGKDGYSIIEQGKVDEILSNNPLSRRKV
                     FDEACGISKYRYKKQEAERNLSNTKENLERIDDVYIEIENQLKPLFNQQTKAKKYLEI
                     SEKLKTLEVNSFIREIEGIEKELSEVNEHRKVIEKELNEKEEQKNVVEKKQEDINKEV
                     EVLQDVIEKSVDYINSIKGVISKKESQINLIKERIRNFTNEISRKNLEINDIKEKLNE
                     NKQYIKELESNKLSGSEELSTLQENIKVLEASKDKQKIKLESLNNEIELLKESIIDIL
                     NKKQEFSNKLSTLNANKENMNIRDENINSEITELNKNIEIKSSELDTINKEFNMQNEN
                     LKNVNNRHKELSTNLQDSISEHNKLEDEIQKSKYNLNGYNSKLNVYIDMENHYEGFNR
                     GVKEVLKNKNLKGVHGALGQIINVPEKYEKSIEAALGAYMQNIITDNEFSAKSAINYL
                     KQNNLGRVTFLPLNIIKSNKISLGNLKANTKFIGIASDLITFDEKYRNIIENILGRTI
                     LINNIDEGIKFAKETGHRFKIVTLDGEILNPGGSLTGGSLKTNGNILSRKRYINEYTE
                     KISNIKNEISHLELKRESLDKDVKNIKNEIDSHESKIKDLEKSIIIKSTSIKNVESEI
                     ESLKGSITKLENEKNDLNSNLNYTLEKSDDVRKDMEELDDLYNKNKEKIDALNEEIKR
                     YNDLYDKEKSEFDELNLSLVKKTEVYNSIVRDIKRISGENCELEEKNKQLEESLNYEE
                     HEIIKLQDSILTEEKEKENLTKQLGDSNRNLETRKIAKDDLKNSFDEINKELKTIDRQ
                     HIELKESLFKVGGRLERLKTSQDTYINKLFEQYDMTLVQALEIKDEDLDIDRKFLESL
                     KREIRSLGNINIDSIKEYEEIKERYDFYSEQKQDLEESMEEIEKLIHTLEENMKSEFE
                     IKFEEISKNFKYVYKRLFGGGCGELTILDKENLLESDILITAQPPGKKMKNLNLLSGG
                     EKALTAISILFAILITKPTPFCILDEIEAPLDDANIFRFGEFLKDLSKETQFISVTHR
                     RGTMEAADYIYGVTMQEKAISKVISLKLKEAQEITDII"
     gene            10292..11572
                     /gene="ftsY"
                     /locus_tag="PC512_003000"
     CDS             10292..11572
                     /gene="ftsY"
                     /locus_tag="PC512_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HDF2442730.1"
                     /translation="MLKKLFGFGKDKEKEIEKKDAEEEIEVEDSVDNLENLEETIFSG
                     LEEEVIDKVEDVEEKNEESVNNEGTEEIENFEKIEVEMDSNGKEVENISNNDSQEEII
                     EELENYDEIESKEIEDKEDKKVNLFERLKQGLTKAKQGITDRIDEVLKSYTKIDEELL
                     EDLEEILITADVGVNTTMDIIERLRDKIKQKGITEPIKVREELKSIVEDILTNENSTL
                     DIEPVPCIILMVGVNGVGKTTTIGKLANRYKKDGKKVLLAAADTFRAAATEQLEIWAN
                     RTNVDIIKHQEGADPGAVVFDAIKAAKARKTDVLICDTAGRLHNKANLMNELGKVFKI
                     VDREFPEAKREVLLVVDATTGQNAVVQAKTFKEVADITGIVLTKLDGTAKGGVVLAVK
                     SEVDVPVKLIGVGESVEDLQDFNAKSFSDALFGN"
     gene            11675..12043
                     /locus_tag="PC512_003001"
     CDS             11675..12043
                     /locus_tag="PC512_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HDF2442731.1"
                     /translation="MNIEKMVEIGLLFEQYKELLTDKQKEIVALYYEEDYSLGEISEN
                     LNVSRQGVYDTLKRSEKILRDYEEKLHLVSKIQEQEKNIKIIKDKIIDIKEDLLHNRD
                     CANLIPKLENIEDVCREMIK"
     gene            12040..13392
                     /gene="ffh"
                     /locus_tag="PC512_003002"
     CDS             12040..13392
                     /gene="ffh"
                     /locus_tag="PC512_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HDF2442732.1"
                     /translation="MIFEGLSDKLQGAFSKLKSKGKLTEVDVKNAMREVKLALLEADV
                     NFKVVKDFIKKVQERCVGQEVMQSLTPAQHVIKIVNEELTSLMGDVQSKVMISSKPPT
                     ILMMVGLQGAGKTTTAGKLGGYFKKQGKKPLLVACDIYRPAAIKQLQVVGEKLDIPVF
                     NMGDKENPVNIAKAGLSHAIKNANDLVIIDTAGRLHIDEVLMDELKSIKSEVKPHEIL
                     LVVDSMTGQDAVNVAESFNEALGVDGVVLTKLDGDTRGGAALSIRAVTQKPIKFMGMG
                     EKLDDIEPFHPDRMASRILGMGDVLSLIEKAQENIDLEKAKELEQKIKKQELDFEDFL
                     QQMEQIQNMGPLDKILGMIPGMGNVKDQLGDVDLNGKEMKRTKAIIQSMTTYERRNPG
                     VLNASRKKRIAKGSGTSVQDVNRLIKQLNEMKKMMKMFAGSQKSMKKRGGLGGLPFFK
                     "
     gene            13430..13702
                     /gene="rpsP"
                     /locus_tag="PC512_003003"
     CDS             13430..13702
                     /gene="rpsP"
                     /locus_tag="PC512_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HDF2442733.1"
                     /translation="MAVKIRLKRMGANKKPFYRIVVADSRAPRDGKFIEEIGYYNPIS
                     EPKQVRINDEKAIKWLATGAQPTEVVKKLLVKNGVIEKFEASKQAK"
     gene            13767..13994
                     /locus_tag="PC512_003004"
     CDS             13767..13994
                     /locus_tag="PC512_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HDF2442734.1"
                     /translation="MKELVVDIAKALVDNPDSVVVEEFEDNDGIVLKLTVAQEDMGKV
                     IGKQGRIAKAIRTVVRSVANRENIKVSLEIV"
     gene            14102..14617
                     /gene="rimM"
                     /locus_tag="PC512_003005"
     CDS             14102..14617
                     /gene="rimM"
                     /locus_tag="PC512_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA processing protein RimM"
                     /protein_id="HDF2442735.1"
                     /translation="MKEKLTHFKVGQIVNTQGLKGEVRVYPLTDDIERFDELKDFYLG
                     KDLNNKLAVEKVRYKGSMVIMKIKGIDSIEKAEKLKNKFMYVSREDSRELEEGEFFIA
                     DMIGMEVLTVDGKYVGILEDVLQYSANDVYVVKGEEDKEFMIPAIKKFVPTIDIDERK
                     MIIDPIKGMID"
     gene            14626..15321
                     /gene="trmD"
                     /locus_tag="PC512_003006"
     CDS             14626..15321
                     /gene="trmD"
                     /locus_tag="PC512_003006"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HDF2442736.1"
                     /translation="MRFHIMTLFPEIFNSYMDESIMKRAVEKGIIEVHIYNIRDFSNN
                     KHKKVDDYPFGGGAGMVMTPQPIYDTYKHIITTHNINNPSVIYLTPKGKVYNQSMAKQ
                     MSLKEDIILLCGHYEGIDERIIDLIVTDEISIGDYVLTGGELPALIMIDSISRLIPGV
                     LNQEESFEEESFKDNLLEYPHYTRPRDFEGLKVPEVLLSGNHKKIDEWRREESIRITK
                     ERRFDLYKKSNEK"
     gene            15506..15856
                     /gene="rplS"
                     /locus_tag="PC512_003007"
     CDS             15506..15856
                     /gene="rplS"
                     /locus_tag="PC512_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HDF2442737.1"
                     /translation="MNEMLRAIEQEQLKNEVPNFGPGDTVKVHVRIIEGKRERIQVFE
                     GVVLKRQGGGARETFTVRKMSFNVGVERTFPVHSPKIEKIEVTRKGKVRRAKLNYLRG
                     RVGKAAKIKEARNK"
     gene            16177..17073
                     /gene="ylqF"
                     /locus_tag="PC512_003008"
     CDS             16177..17073
                     /gene="ylqF"
                     /locus_tag="PC512_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HDF2442738.1"
                     /translation="MSNEYEEYLMDDNLHINWYPGHMKKTKELVKNNLKLIDVVIELL
                     DARIPFSSKNPDIDRLVGDKPRVVVLNKSDMADRDKLNQWIEYYKKINIKAIPVDTIK
                     GVGINKIIEECKNVTREKMSSLKDKGRKERAIRIMIVGVPNVGKSSLINKLTGRKSTQ
                     TGDKPGVTKGKQWVRLKGNLELLDTPGILWPKFEDQEVALNLAFSRAIKDEILDTETL
                     ALRLIEKLMKIEPEKLKARYKLDCLGETPIETMDMIGHKRGFITGKKELDYTRIATTV
                     LNEFRDGKIGNITLEVPENVKR"
     gene            17462..18754
                     /gene="brnQ"
                     /locus_tag="PC512_003009"
     CDS             17462..18754
                     /gene="brnQ"
                     /locus_tag="PC512_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HDF2442739.1"
                     /translation="MGKTKDVIVFGFALFAMFFGAGNLIFPPYLGIITGPEWLIAFLG
                     FTFADAGLALLAVMATAKFDGNVVEMFKRCGMKLGILIGCADILCIGPFLAIPRTGAT
                     TYEMGIMPLFGTSIPVLLFCILFFALSYVLTIRPSKVVDIVGQFLTPALLIALAFIII
                     KGIISPLGDIVDKPMIPNVFAEGIGQGYQTMDAFAAIALASVLIVSLNDKGYSTISDK
                     LKMIGKAGVLACGGLALVYGGLCFLGATVSTMYGTDAVQSQVIVNITEGLLGNVGKAI
                     LAVVVSLACLTTSIGLTSATGQYFSRLTKGKLSYEKIVLAVSVFSAVVASFGVGTIIK
                     IASPILSIVYPPSIVLIILAFFNEKIKNDNVYKGAVYMSLLVSILTVISSYGVAVPVV
                     NSLPLNSLGFNWVVPVIIAGIIGNFIPSKSQSNTLGTN"
BASE COUNT         7966 a         1761 c         3465 g         5643 t
ORIGIN      
        1 tacacattaa tatctataaa atgacaaaat aaaaaatact atttaaatag atattaaaaa
       61 attgatacca agtatttgtt tgctatatga ataacaattt atttaggagc tttacttgga
      121 cactgtataa taataaagta attgctaaaa acgtttgatg atttggatgt atttttagaa
      181 attagaaaaa tatatactta ctgactaatg ataatcttat atgtatttta gtttgagtga
      241 tttaagaaaa gtgttttgaa tggggattat tttatagagt aaataaatat ataatagtag
      301 aaaattacat ataaagagta gtatttattt cattaccttc tttatctgtt ccgatagggt
      361 cttgtagaga tacttgagtt ttattttttt tgttagatct aatattcatt aaaatctcat
      421 tttcaataca tctagaagca tatgttgcta atcgagttcc tttatctatg ttataagttt
      481 ctatagcttt aattaatcct attgtaccta tggatattaa atcatcctga tcttccgttg
      541 aattattata tttctttgct atataagcta ctaatctcat gtttctttca attaatgtat
      601 cttttgcact tttatcgttt tctattttaa atttagttaa atactcaatc tcttcttcag
      661 gggttaaggg tttttcaaaa gatttaagag ctgccaatag gtcaccccct tttcaacggt
      721 cactttaaat tatatgaagg agacttatcc aagttgactg ttatctaata aaataatatg
      781 catattttta gaatttaaaa catatatttg caaacttttg aatggaatat gacataaaga
      841 gtgggaattt aaatttaagt ttttgttgta tatatatgaa acaaggcgaa gaaattattg
      901 atttataaag tataaattgg aattgaggtg tcaataaata taaaaggaaa tagtatttat
      961 atatgttttg gtgttgaagt aaaagattaa tgcaaagcat tagagtctat aaaaatatga
     1021 atataggagg tgtaatttta caatacttaa aaaagtaaat gtaattaatt gtttgtataa
     1081 agttgattac aagcaaaagt atcagtcata gttaatactg ttaaggatga aggtggtgtg
     1141 ttaatttata tatgtatggg aagaaatttt gattacaatg aaaaaactta caaaagatat
     1201 ttacgaaaaa acttatagtt aaatgtttat atataaaata ttatttaggg gttgttttta
     1261 ttattgaaaa taagaaagag tggttttata tcaattgaat gtataataag tattgctata
     1321 ttatatgtgg ctgtttattt agtttctaca tcattgtata attgttatag ttttatcagt
     1381 agaaatatat ctgacagaga aatgttaagt acagcaaaaa aatatataga agatgagaag
     1441 tatagaatac aaaatagtaa gtatgagtta attgaagata agatagaaaa aaattacata
     1501 aatggatatg aaattaacag tagaatagag caaattttag attattatca atgctatgaa
     1561 ataaatatag agataaaaaa tgaatttaaa aaactgaggt ttaatagcta tgttactaga
     1621 aaataaaggc tctatattaa taataacatt gataatattt tctattataa gtactgtgtg
     1681 cattatgtgt ataggtttaa tttatacaca taataatatg tttgagttag gatacaaaga
     1741 cattcaacta aaagaaattt ctttaagtgg aatagaaata tcagtaagta atgtactttc
     1801 ttgtgttgag gaagctattg atatatctaa taatgaagac gaatttagag aatatttctt
     1861 aggaaataat atgattgaat gtataaaaaa aataaaagat acatcttata gtagtttaga
     1921 agaactttct ttaaaagtag aaaataatac tatttatgac agaggagatt tttttgaatt
     1981 tgatatagaa agtaatgtta gagaaaaaga atttttaaaa gcaataaaag taagagtgaa
     2041 aatcaaaaat ccatggatag gaattgatat tgaagattat atggataaat ctaataacaa
     2101 taaaattgat gacaaaacat tcaataatta taaagcatct gaaaataatg aaattataaa
     2161 tcaatttaaa aatgaaagtg aaaatataag gaatcaagag gttgttgaat ttacagaaga
     2221 agatgaagaa gaacttaaac aaaacataat tgaaaatata aagaagaatt ttgatgaaaa
     2281 aaacctagta caggtatata agtatagggg tgtataactt tgaaaaaaga aggaatgtga
     2341 ctgtaataga attaatagta tctatcagta taatactctt gatagttaca ttatcttttc
     2401 caaaagataa tcttgaaaat cataaaataa atttatttgc acgtcaactt tgttcagata
     2461 taaggtatgt taggcgaatt aatatgttta gcaactacaa tacatatata tattatataa
     2521 atcaaggtaa acacgaaggt tatgtattga gaaaagatgg taaaaacatt aaatcaataa
     2581 tgctacctaa aaatgcaaaa atagctagga gtattgaaat aataaagttt aaatctgatg
     2641 ggtcgcctca aaaggcgtct acaatagagg tatataataa tagattaaga aaaactataa
     2701 caataacacc tgtaagtgga agagtacttc tgaaagaggg aaaatatgaa acataaatat
     2761 ggttacttgc ttttggaaag tgtcgtatca ttgtcttcaa tggtgataat tatactagtt
     2821 ttatattcta tatttttgtc tacaataaac ttaaagttaa aagtagaaga taagatagaa
     2881 ctacaacaac aaagtcttga aatcataaaa tctatggaag gaattattag caattctatg
     2941 ggaataatga atgtatctaa ttatgaagaa acatttaaaa agacaacatc tataaaatgt
     3001 agatatttag atgaaaataa taatgaagaa ggcataagta ataaagaaat tatattgaat
     3061 gaaagacgaa ataagttatt tgtaaattct ttaaatggcg aaagtagtca agcaggtggt
     3121 tatgaaattg gagattatgt agatgaaatg tatgtatcaa ttactaataa tggtcaatac
     3181 gttaatatta aattgaaatt atcaaaatgt agtcaaaaat atgagactga tttcaaaata
     3241 aaagtatgga attttagtga aagtatataa aaatacataa atttaagaga aagaaatgac
     3301 atcaataagt catataaaat ataattattg agaactatat aactaaataa tatcaatatg
     3361 taaagtgtat agattaagaa tatagaggat aataataaaa atatagaata agtaatttgc
     3421 caaatacttg tttatattgt ataacttatg atattatgat attagtaaaa atttgtaatc
     3481 ctgacttgac agaattcaag taagagatat aattttaaag gcatagtaat gtaaaattta
     3541 ctaaaaaata agaaatttat tttaatatgg aggaacaaaa aatggtatca gcaggtgatt
     3601 ttagaaaagg tgttacattt gaaaaagatg gacaaccatg tttagtagtt gattttcaac
     3661 acgttaagcc aggtaaagga gctgctttcg ttagaactaa atacaaaaac ttaaaaacag
     3721 gagctataag agaagaaagt ttcaatccaa gtgaaaaatt ccctaaagct gttatagata
     3781 caagacaaat gcaatatcta tacaatgatg gtgagttata ttattttatg gatcaagaaa
     3841 attttgaaca aataccatta aactatgagc aagttgaaga tgcaattaag ttcttaaaag
     3901 aaaatgaagt tgctacaata agattttacc aaggacaacc attccaagtg gaagcgccaa
     3961 actttgcaga gctagaagtt acagatacag agccaggcat aaaaggtgat acagcaagta
     4021 atgtaactaa agcagctaca gttgaaactg gagcagttgt tcaagttcca ttatttataa
     4081 atactggaga taaagtaaag atagatacta gaacaggtga atatttatca agagtataaa
     4141 aatttatgta tataaaagct tatatgtctt aataatataa gatatatgag cttttagttt
     4201 atatataaaa aagaaagcga ggggtgttac atgaaacatt tatatgaaga agttgcatac
     4261 ttaaaaggcc tagcagaagg actagaaata agtgctgaaa gtaaagaagg gaaaatgata
     4321 cataaaatag ttgatgcatt agaagtattt gcagatgcta ttgtaacatt ggatgaagaa
     4381 caagaagaac ttcaagattt tgttgaatct atagatgaag atttagcaga tttagaagaa
     4441 gatattgctg acatggaaga agatctttat gaagaagatg acgatgagga tgatgaggac
     4501 ttcagctata tagaaatgga atgcccaaat tgtggagagt tagtagaaat agacgaagat
     4561 ttgttatatg atgatgaagt agatgttgtt tgtcctgatt gtaaggctgt gatattatca
     4621 tcagaagatg attgtgatga tgattgtaca tgtggtggtt gttcaagttg tgatgataga
     4681 gagtaaaaat tcataagaat taaaactgcc tatgatgcct atgagatatt ttgcttcata
     4741 ggtagtttta tttttatgag gaagggtatt atgtattttg gttttgcaat acttggacaa
     4801 aaatagtaca ctagaattta tagaatagga ttttggaggg atgtaaatat gaaaataagt
     4861 aaaaaattac tagataatat acaaagattt gaaaatgtta taaattataa atttaaaaat
     4921 aaagaatata tactagaagc tcttactcat agttcatatt ctaatgaaaa taaaaaatat
     4981 aattttaacg aaagattgga atttttaggg gattcggttt taggcatagt gataagtgat
     5041 tatttattta atgaagaagc taatctgccc gaaggggaac taactaaact tagagcaaat
     5101 atagtctgtg aagattcatt aagtgaagta gctaatgata taaatttagg tattcacatg
     5161 ttattaggta gaggagaaga agcaacagga ggaagacata ggacttcaat attagcagac
     5221 gcatttgaag ctgtaatagc tgctatatat cttgatggag gttttgaaag tgcaagacag
     5281 tttatacttc atcatatgga aaatataatt tatgattcaa gaaaaggaaa tatatttaga
     5341 gactacaaaa cgcatcttca agaggtgtta caagggaatg gagaaaataa tatctggtac
     5401 aggcttatag aagaaaaagg accagaccat aataaaagat ttgtaatgga agttggaatt
     5461 aatgacgatg tacttggtat aggagaaggc aagagtaaaa aagaagctga acagttagct
     5521 gctaaaatag ctttaaagaa aaaattatgg gaaaaataaa tataatatgt aaaaatataa
     5581 aaagaaatat ttatattaga aggatgttgt agatgaaaaa gagaattata cctatatttg
     5641 ttcctcacaa aggatgtcct catgattgca tattttgtaa tcaaaaaaaa ataacaggtg
     5701 tgagtactga tgttactagt gaagatgcaa gaaatataat tgaggaatgt ttagagacta
     5761 tagataaaga tgcagatgta gaaatagcat tttttggtgg tagctttact gctatagata
     5821 ttgatataca aaaaagttta ttatcagttg ctaaagaata tgtagaaaaa ggtcttgtaa
     5881 aagatattag aatgtctaca agaccagatt gtattgatga agatatatta agtatgttaa
     5941 aagaatataa gacaagtata attgaactag gagtacaatc cttagatgaa aaagtattat
     6001 tagatagtat aagaggtcat caatctgaaa ttgtatacaa gagttcaaag atgataaaaa
     6061 atagtggaat caaacttgga ttacagatga tgattggtct tccagctgac acagaagaaa
     6121 agtgtatatt tacagcaaaa aaatttgtag agctaaaacc agattgtgtt agagtctatc
     6181 caactttggt agtaaaagat acaggtcttg aaaagttaat ggaacaaaat aaatataatc
     6241 catttaccct tgaagagagt gtaaatatag taaaaaaagt tcttgtactg ttttatgtta
     6301 ataatatcaa tgtaataaga gttgggcttc aagctactga tgatatacaa attggaaaag
     6361 ctgttttagc aggaccatat catcctgcat ttagagagtt ggtagaagca gatatgataa
     6421 aagattattt agaatttgtt attttgcaaa ataaaaatat aaagcaaatg ttggtcaaat
     6481 ctaataaaaa gaatatttct aaaatcatag gaaataaaaa aacaaatgtt aaatatatgg
     6541 aagaaaaatt tggtgtgctt ttaaaaacac aagaatcaga tttagatata aatcaattag
     6601 aaattgtgtt agatgggaaa agtttaatta gtgctaatat gagagacatt catagaaaat
     6661 tgtatgacat ttatgacctt tagttttaat aatgaaggga gagaaaagat ttgtatttaa
     6721 aaagactaga gttaaaggga tttaaatcct ttccagtaaa aacagatatt atttttaaag
     6781 aaggaataac agccatagta ggaccaaatg ggagtggaaa aagtaatata tctgatgctg
     6841 taagatgggt attaggagaa cagagtatta agagtcttag aggtgataaa ctcgaagatg
     6901 taatatttgc aggtacagat acaaaaaaac ctatgaatta ttgtgaagtg gctcttacta
     6961 ttgataattc tgaaaatcaa ttggaattag attttacaga agtaactata agaagaaggg
     7021 cttatagaaa tggtgaaagt gaattttttc taaataataa aagttgtaga ttaaaagata
     7081 taaaagaagt ctttttagat actggtattg gaaaagatgg ttattcaatc atagaacaag
     7141 gaaaagtaga tgaaatatta agtaataatc ctttaagcag aagaaaagtt tttgatgaag
     7201 cttgtggcat atcaaaatat agatataaaa aacaggaagc agaaaggaat ttaagtaata
     7261 caaaggaaaa tttagaaaga atagatgatg tatatataga aattgaaaat caattaaagc
     7321 ctctttttaa tcaacagaca aaggcaaaaa agtacttgga aataagtgaa aaattaaaga
     7381 cacttgaagt aaatagcttt ataagagaaa ttgaaggaat agaaaaagaa ttaagtgagg
     7441 ttaatgaaca tcgtaaggtt attgaaaagg agctcaatga aaaagaagaa caaaaaaatg
     7501 ttgtagagaa aaagcaagaa gatattaata aagaggtaga ggtattacaa gatgtaattg
     7561 aaaaatctgt agattatata aattcaatta aaggagttat atcaaaaaaa gagtcccaaa
     7621 taaatttaat taaggaaaga ataagaaatt ttacgaatga aattagtaga aaaaatttag
     7681 aaataaatga tataaaagag aagctaaatg aaaataagca atacataaaa gaattagaaa
     7741 gcaataaatt atcaggtagt gaagaactat ctaccttgca ggaaaatata aaagtattgg
     7801 aagcaagtaa agataaacaa aaaattaagt tagaatccct aaataatgag atagaattat
     7861 tgaaagaaag tataattgat atattaaata aaaaacaaga gtttagtaat aagctgtcca
     7921 ctttaaacgc aaataaagaa aatatgaata tcagagatga aaatataaat tcagagataa
     7981 cagagttaaa caaaaatatt gaaataaaat catctgaatt agatactata aataaagaat
     8041 ttaatatgca aaatgaaaat ttaaagaatg taaataatag acataaagaa ttatcaacta
     8101 atttgcagga ttcaattagt gaacacaata aactagaaga tgaaatacag aaaagtaaat
     8161 ataatttaaa tggatataat tcaaagttaa atgtctatat agatatggaa aatcattatg
     8221 aaggatttaa tagaggagta aaagaagtac taaaaaataa aaatttaaaa ggagttcatg
     8281 gagcattagg acagattata aatgtacctg aaaaatatga gaaatctata gaagcagctc
     8341 ttggtgctta tatgcaaaat ataataactg ataatgagtt tagtgctaag tctgcaataa
     8401 actatctaaa acagaataat ttaggtagag taacatttct tccattaaat ataattaaat
     8461 caaataaaat aagtctagga aatttaaaag caaatactaa gttcatagga atagcaagtg
     8521 atttaattac atttgatgaa aagtatagaa atataattga aaatatactt ggaagaacaa
     8581 tacttataaa taatatagat gagggcataa aatttgcaaa agaaactggt cataggttta
     8641 aaatagtaac tttagatggt gaaatcttaa atccaggagg ttctttgact gggggaagtc
     8701 taaaaactaa tgggaatata ctatccagaa aaagatacat taatgaatat acagaaaaga
     8761 taagtaatat caagaatgaa atttcacatc tagaattaaa aagagaatct ttagacaaag
     8821 atgtgaaaaa tatcaaaaat gaaattgatt cacatgaaag taaaataaaa gatttagaaa
     8881 aaagtataat aataaaaagt acaagtataa agaatgttga gtctgaaatt gaatcgttaa
     8941 aaggtagtat tactaaatta gaaaatgaga agaatgattt aaattctaac ctaaattata
     9001 cacttgaaaa aagtgatgat gttagaaaag atatggaaga gttagatgat ttatacaata
     9061 aaaataaaga aaaaattgat gcattgaatg aggaaataaa aagatacaat gatttatatg
     9121 ataaagaaaa atctgaattt gatgaattga acttaagttt agtgaagaaa acagaagttt
     9181 acaatagtat agttagagat ataaaaagaa tatctggtga aaattgtgag ctagaagaaa
     9241 aaaataaaca attagaagag tcattaaatt atgaagaaca tgaaataatt aaattacaag
     9301 attctatact cactgaagaa aaagaaaaag aaaatttaac aaaacaacta ggggatagta
     9361 atagaaatct tgaaactaga aaaatagcaa aagatgattt aaaaaatagt tttgatgaaa
     9421 ttaataaaga attaaaaact atagatagac agcatataga acttaaagaa agtttattta
     9481 aagttggtgg aagattagaa agattaaaaa ctagtcaaga cacatatata aataagttgt
     9541 ttgagcaata tgatatgacc ttagtacaag cattggaaat taaagatgaa gatttggata
     9601 tagatagaaa attcttagaa agtctaaaga gagaaataag aagtcttgga aatataaata
     9661 tagactctat aaaggaatat gaggaaataa aagaaagata cgatttttat agcgaacaaa
     9721 agcaagattt agaagagtct atggaagaga tagaaaaact tatacatact ttagaagaaa
     9781 atatgaaatc tgaatttgaa attaagtttg aagaaataag taaaaatttt aaatatgtat
     9841 ataagagatt atttggtgga ggttgtggag aattaactat tttagataaa gaaaatttat
     9901 tagaaagtga tatactaata acagctcaac ccccaggtaa aaaaatgaaa aatttaaacc
     9961 tattatctgg tggagagaaa gctttaacgg caataagtat attatttgct atattgatta
    10021 caaagccaac accattttgt atattagatg agattgaagc gccacttgat gacgcaaata
    10081 tatttagatt tggagaattt ttgaaggatt tatctaaaga gactcaattt atatcagtaa
    10141 ctcataggag aggaactatg gaagctgctg attatatcta cggagttaca atgcaagaaa
    10201 aagccatttc aaaagttatt agtttaaaat taaaagaagc tcaggaaata acagatatta
    10261 tataacttag attgacatag gaggaataac agtgttaaaa aaattatttg gttttggaaa
    10321 agacaaggaa aaggaaatag aaaaaaaaga tgctgaagaa gaaatagaag ttgaagacag
    10381 tgttgataat ttagaaaact tggaagaaac tattttttca ggacttgaag aagaagtgat
    10441 agataaagtg gaagatgttg aagaaaaaaa tgaggaaagt gtcaataatg aaggcactga
    10501 agaaatcgaa aactttgaaa aaatagaagt tgagatggat agtaatggaa aagaagtaga
    10561 aaatatttca aataatgatt ctcaagaaga gataatcgaa gaattagaaa attatgatga
    10621 aattgagtct aaagagatag aagataaaga agataagaaa gttaacttgt ttgaaagact
    10681 aaaacaagga ttgacaaaag caaagcaagg aataactgat agaatagatg aagttttaaa
    10741 atcatataca aagatagatg aagaattact tgaagattta gaggaaattt taataacagc
    10801 agatgttggt gtaaatacaa ctatggatat aattgaaaga ctaagagata aaataaagca
    10861 aaaaggtatt actgaaccaa taaaggtaag agaagaactt aaatctatag ttgaagatat
    10921 tcttacaaat gaaaactcta cactagatat agaaccagta ccatgtataa tattaatggt
    10981 gggtgtaaat ggggtcggta agactactac aataggtaaa ctagcaaata gatacaaaaa
    11041 agatggtaaa aaagttttat tagcagcagc agatacattt agagcagcag caacagagca
    11101 attagaaatt tgggcaaata gaaccaatgt agacataata aaacatcaag agggagcaga
    11161 ccctggagct gtagtatttg atgctataaa agctgcaaaa gctagaaaaa cagatgtatt
    11221 aatatgtgat acagcaggaa gattacacaa taaggctaat cttatgaatg aacttggaaa
    11281 agtatttaaa atagtagata gagaatttcc agaagcaaaa cgagaagtac ttcttgtggt
    11341 ggatgctaca acaggtcaaa atgcagttgt tcaagcaaag acatttaaag aagttgcaga
    11401 tataacaggt atagtactta caaaacttga tggaactgca aaaggtggag tagtccttgc
    11461 ggtaaaatca gaagtagatg tacctgtaaa acttattgga gttggagaaa gtgtagaaga
    11521 cctacaagat ttcaatgcaa aatcattttc agatgcatta tttggtaact aatgttcttt
    11581 taaaaataat ggttgacaag agtgttgtta tgatataaaa tacaatagtg taaagtaaat
    11641 aacctttaca gtatactgct aggaagtgta agatatgaat atagaaaaaa tggtcgaaat
    11701 tggattgtta tttgaacagt ataaagaatt attaactgac aagcagaaag aaatagttgc
    11761 tctatactat gaagaagatt attctttagg tgaaattagt gaaaatctga atgtatcaag
    11821 acaaggtgtt tatgatacct taaagcgttc agaaaaaata ctaagagatt atgaagaaaa
    11881 gttacactta gtatcaaaga ttcaagagca ggaaaaaaat attaagatta taaaagataa
    11941 aattattgac attaaagaag atttattgca caatagagat tgtgctaatt taatccctaa
    12001 gctagaaaat atagaagatg tatgtaggga gatgataaaa tgatatttga aggattgtct
    12061 gataaactac aaggggcatt tagtaagtta aaatctaaag gaaaacttac agaagtagat
    12121 gtaaaaaatg ctatgagaga agttaaactt gctcttcttg aggcagatgt taactttaaa
    12181 gtagttaaag atttcataaa aaaagttcaa gagagatgtg ttgggcaaga agttatgcaa
    12241 agcttaactc cagctcagca tgtaatcaaa attgtaaatg aagagcttac aagtttaatg
    12301 ggagatgtac aaagtaaagt aatgatttcc tcaaagcctc ctacaatttt aatgatggtt
    12361 ggattgcaag gtgcaggtaa gactactaca gcaggaaaac ttggaggata ttttaaaaag
    12421 caaggtaaaa aacctctatt agtagcttgt gatatttata gaccagcagc tataaagcaa
    12481 cttcaagttg ttggagaaaa attggatata cctgtattca atatgggaga taaagaaaat
    12541 ccagtaaata ttgcgaaagc aggtttaagc catgcgatta aaaatgctaa tgatttagtt
    12601 attatagata cagctggtag acttcatata gatgaagtac ttatggatga gttaaagtct
    12661 attaaatcag aagttaagcc acatgagata cttttggttg tagattctat gacaggtcaa
    12721 gatgctgtaa atgttgcaga aagcttcaat gaggcacttg gtgttgatgg agtagtatta
    12781 actaaattgg atggagatac tagaggaggt gctgcacttt caataagagc agttacacaa
    12841 aagcctataa aatttatggg gatgggagaa aagctagatg atatagaacc tttccaccca
    12901 gatagaatgg catcaagaat attaggtatg ggagatgtct taagtttaat agaaaaagca
    12961 caagaaaata tagatttaga gaaagctaaa gaattagagc aaaaaattaa aaaacaagag
    13021 cttgattttg aagatttctt acaacaaatg gaacaaatac aaaatatggg acctcttgac
    13081 aagatacttg gtatgatacc tggtatggga aatgtaaaag accaacttgg agatgtagat
    13141 ttgaatggca aagaaatgaa gagaacaaaa gccataattc agtcaatgac tacatatgag
    13201 agaagaaacc caggagtatt aaatgcttca agaaagaaaa gaatagctaa aggcagtgga
    13261 actagtgtac aagatgtaaa tagacttata aaacaactta atgaaatgaa aaaaatgatg
    13321 aagatgtttg ctggttcaca aaagagtatg aagaaaaggg gcggcttagg cggtttacct
    13381 ttttttaaat aaaatataaa aaagtaaaaa ttattcggag gtgactgtaa tggcagttaa
    13441 aataagatta aaaagaatgg gagctaacaa aaaacctttc tacagaatag tagtagctga
    13501 ttcaagagct ccaagagatg gaaaatttat agaagaaata ggatactata atccaatttc
    13561 tgaacctaaa caagtaagaa taaatgatga aaaagctata aaatggttag ctactggtgc
    13621 tcagccaaca gaagtagtta aaaaattact tgtaaaaaac ggagtaatag aaaaattcga
    13681 agcttctaaa caagcaaaat aattttttct tggcaattag tttaagtaag ggctcattgc
    13741 taaggttact ttaggagatg aaatatatga aagagctagt tgtagatata gctaaggctc
    13801 tagttgataa tcctgactca gttgttgttg aggaatttga agataatgat ggtatcgtct
    13861 taaagcttac agttgctcaa gaggatatgg gtaaggttat tgggaagcag ggaagaatag
    13921 ctaaagctat aagaactgtc gtaagatctg ttgcaaatag agaaaatata aaagtttctc
    13981 ttgagatagt ataaaatagg aggattaggt ataatgccta gtccttttta tataaatgcg
    14041 tagtttaaga ttttatgatg atatgaccac ataagattaa attttttaag aaggtgataa
    14101 catgaaagaa aaattaactc attttaaggt aggtcaaata gtaaatacac aaggtttaaa
    14161 aggtgaagta agagtttatc cgcttactga tgatatagag aggtttgatg aattaaaaga
    14221 tttctatctg ggaaaagatt taaataataa attggctgtt gaaaaagtaa gatacaaagg
    14281 ttctatggtt ataatgaaga taaaaggcat agacagcata gagaaagcag aaaaactaaa
    14341 aaataaattt atgtatgtat ctagagaaga tagcagagag cttgaagaag gcgaattttt
    14401 tatagcagat atgattggaa tggaagtttt aactgtagat ggaaaatatg taggaatact
    14461 agaagatgtt cttcaatact cagcaaatga tgtctatgta gtaaaaggtg aggaagataa
    14521 agaatttatg ataccagcta taaaaaaatt tgtacctaca atagatattg atgaaagaaa
    14581 aatgattata gaccctatta agggaatgat agattaggtg gtaatatgag atttcatata
    14641 atgacacttt ttccagaaat atttaattcg tacatggatg aaagtataat gaagagagca
    14701 gttgaaaaag gtataattga ggttcatata tataatataa gggatttttc taataataaa
    14761 cataaaaaag tagatgatta tccatttgga ggaggagcgg ggatggtaat gactcctcaa
    14821 cctatatatg acacatataa gcatataata acaactcata atataaataa cccaagtgta
    14881 atttatctta ctccaaaagg taaggtatac aatcaatcta tggcaaagca gatgtcttta
    14941 aaagaagata taatactact atgtggtcat tatgaaggaa tagatgagag aatcattgat
    15001 ttaatagtta ctgatgaaat ttcaattgga gattatgtat taactggggg agagctccca
    15061 gcacttataa tgatagattc tatatcgaga ttaataccag gtgtattaaa ccaagaagaa
    15121 tcatttgaag aagaatcatt taaagacaac ttattggaat atcctcatta cactagacct
    15181 agagattttg aaggattaaa agtaccagaa gtgcttttat cagggaatca taagaagata
    15241 gatgagtgga gaagagaaga atctataagg ataaccaaag aaagacgatt tgatttatat
    15301 aaaaagtcta atgaaaaata aaaatataat gaaaaattaa tatatatgta tacaataaag
    15361 tacctataaa tggaattaaa aacataaaag tgcttgtaat aactattgaa gtatagtata
    15421 atataaaatg ttgaaaatac gggcgttcct ctgtttacac tggtcgggta gttaagaacg
    15481 tctatgatat ctaggaggaa gaaagatgaa tgaaatgcta agagcaattg agcaagaaca
    15541 attaaaaaat gaagttccta attttggacc tggggacaca gttaaagtac acgttagaat
    15601 tatagaagga aaaagagaaa gaatacaagt attcgaaggt gtagtattaa agagacaagg
    15661 tggaggagca agagaaactt tcacagttag aaaaatgtct ttcaatgttg gtgtagaaag
    15721 aactttccca gttcactctc caaaaataga aaaaatagaa gttactagaa aaggtaaagt
    15781 aagaagagct aaactaaact acttaagagg tagagtaggt aaagctgcta agataaaaga
    15841 agctagaaat aaataattaa aaactttact tataaatggg gggctgattt atcagtcctc
    15901 tttctatttt aatgaaaatt acaacaaata attatactag aaataaatag aaatatttgt
    15961 tgaaaatata gattatttat ctatgaattt atagctttta aaatgaaaaa taaaattggt
    16021 aaatattgca ttatattttg taacgatatt aaaaataaga gaacagtatt atgtaaagta
    16081 tgacgttaaa aagatgacaa tattatagtt tgtgaagata tattttttaa gtggaattag
    16141 gatataataa tataatatta ataaggagtg atacatgtgt caaatgaata cgaagagtat
    16201 cttatggatg acaatctaca tataaactgg tatccaggtc atatgaaaaa aactaaggag
    16261 ttagtaaaaa ataacttaaa attgattgat gtagtaattg aacttttgga tgctagaatc
    16321 ccgtttagta gtaaaaatcc agacatagac aggcttgtag gagataagcc aagagttgtc
    16381 gtacttaata agagtgatat ggcagatagg gataaattga atcaatggat tgaatactat
    16441 aagaaaatta atatcaaagc tataccagta gatacaataa aaggtgttgg tataaataag
    16501 ataatcgaag aatgtaaaaa tgtaactaga gaaaaaatga gttctttaaa agacaaaggg
    16561 agaaaagaaa gagctatacg aataatgata gttggcgttc caaatgttgg taaatcgtct
    16621 cttataaaca aattaacagg tagaaaaagc actcaaactg gagataagcc aggagtaacg
    16681 aaagggaaac aatgggttag attaaaggga aatcttgaac ttttagatac gcctggaata
    16741 ctttggccta agtttgaaga ccaagaagtt gcattaaatt tagcatttag tagagctata
    16801 aaggatgaga ttttagatac tgaaactttg gctttaagac ttatagaaaa acttatgaaa
    16861 atagaacctg agaagttgaa agccagatat aagttagatt gtctaggaga aactccaatt
    16921 gaaactatgg atatgattgg tcataaaaga ggatttataa caggtaaaaa agaactagat
    16981 tatacacgca tagccacaac tgtattaaat gaatttagag atggaaaaat aggaaatata
    17041 acattggaag ttccagaaaa cgttaaaaga tagattttaa aacaaaatca aaaatttaat
    17101 gttaaaaatt taaaaaagcc ttttagcaaa ggctttttta tttttttgaa atatagacaa
    17161 atatctccat ataaaagtat aaattaggtt agaaagcctt taaaaatatt aatttaagac
    17221 aaatatacct aatattttga aaattaaaat gagtgtgatt attaaaaatt ttagcatatt
    17281 gacttgcttg tttcgtataa tatataataa gcacaaataa atacaatata ttaaaaattt
    17341 aatttattta attttattaa tttaataata agttcttatt gtttaattca acttacttat
    17401 gcaagcgtaa acaatcgaga cattttatta atttaataag gttaaaaagg gggattttat
    17461 aatgggtaag accaaggatg ttatagtatt tggatttgcg ttatttgcaa tgttctttgg
    17521 agcaggtaac ttaatatttc caccttactt gggaataatt acaggtccag aatggttaat
    17581 tgccttctta ggatttacgt ttgctgatgc tggattggca cttctagcag taatggctac
    17641 agctaaattc gatggaaacg tagttgaaat gtttaaaaga tgtggtatga agttagggat
    17701 tcttataggt tgtgcagata ttttatgtat aggaccattc ttagctatac caagaacagg
    17761 tgcaacaact tatgaaatgg gtataatgcc tttatttgga acttcaattc cagtgttatt
    17821 attctgtata cttttttttg cgctttcata tgtactaaca ataagacctt ctaaggtcgt
    17881 agatatagtt ggacagtttt taactccagc tcttttaata gctttagcat ttataattat
    17941 aaaaggtatt atatcacctc ttggagatat agtagataaa cctatgatac ctaatgtatt
    18001 tgcagaaggt ataggtcaag gatatcagac aatggatgct tttgcagcaa tagcacttgc
    18061 atcagttcta atagtatctt taaatgataa aggatattct actattagtg acaagttaaa
    18121 aatgattggt aaggcgggtg ttcttgcttg tggaggatta gctctagttt atggaggatt
    18181 atgtttcctt ggagcaactg tatcaacaat gtatggaaca gatgcagtac aatcacaagt
    18241 aatagtaaat ataactgaag gattgcttgg aaatgttggg aaagcgattt tagcagtagt
    18301 agtatcatta gcatgtttaa ctacatctat aggtcttaca tctgccacag gtcaatattt
    18361 ctctagactt acaaaaggta agttgagtta tgaaaaaata gtattagctg tatctgtatt
    18421 cagtgcagta gtagcatctt ttggtgttgg aactataata aagatagcat ctcctatatt
    18481 aagtatagtt tatccaccat caattgtttt aataatttta gctttcttca atgaaaaaat
    18541 taagaatgat aatgtgtaca aaggagcagt atatatgtca ttgcttgtaa gtatactaac
    18601 agttatatct agttatggag tagctgttcc agtagtaaac tctttacctc ttaattcatt
    18661 aggatttaac tgggtggtgc ctgttataat agctggaata attggcaatt ttataccatc
    18721 aaagagtcaa tctaatacac ttggaacaaa ctaagtttta tttaattaaa atataatcaa
    18781 ttgtaaataa atgagttaac taaaagtaaa aggagttatt tgtacaaata actcc
//
LOCUS       DAMJVG010000082        18697 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.082, whole genome shotgun sequence.
ACCESSION   DAMJVG010000082 DAMJVG010000000
VERSION     DAMJVG010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18697)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18697)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18697
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.082"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(<1..713)
                     /gene="yqeC"
                     /locus_tag="PC512_003010"
     CDS             complement(<1..713)
                     /gene="yqeC"
                     /locus_tag="PC512_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative selenium-dependent hydroxylase
                     accessory protein YqeC"
                     /protein_id="HDF2442740.1"
                     /translation="MELSNIIEKNEIITVVGAGGKTSFINYFANFYRDKLKVLLTTTT
                     KIYVPNDYDNIIITIDGTVIPSICHGITVCGSYINNENKLVSIDSSILDEIVDQFDLV
                     LIEGDGSKRKKLKGWNAKEPVVYHKTTKTIGILDITSFGMNINEENIHRVEIFKKIAN
                     LDTSSINSSSTVSIENLKNIVLNPNGLFKNYSGKRVLFINKVENEKYKNLAIKLVENI
                     KEYESEIEIFYGSVKQKFCV"
     gene            complement(896..2173)
                     /locus_tag="PC512_003011"
     CDS             complement(896..2173)
                     /locus_tag="PC512_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF2442741.1"
                     /translation="MSNRIKNIHYGTQRQQLKNLTKKEYQALREMCFLAKNLYNVGTY
                     NVRQHYFNQGEHLNYEANYHVCKENENYKLLNSNIAQQILKEVDSSFRSFFGLIKLAK
                     EGKYDFRGIKSPKYLDKEGFFSIIIGQIRIKEDGILNVPMSPAFKKLYGKVSIKVPQN
                     ILEKKIKEIRIIPKHKARFFEIQYCYEIPKSEEVSNQKNALAIDLGLENLCTCVTNLG
                     DSFIIDGKRLKSVNQWANKQNDKIEALKLKKNITAITRKQFKVWNKRNNQVKDYVNKT
                     CFYIIDYCVKNNIGNLIVGYNAKLEKSDNMERKIYRNFIRIPFGEIKGKLEYLCKIKN
                     INFIRQEESYTSKSDFFADDFLPDINVDNVKKYDFKGERITRGQYKSSVGIIINADVN
                     ASLNILKKSQVVNLSNLQNNPQILKQPQRVRIS"
     gene            complement(2312..4618)
                     /locus_tag="PC512_003012"
     CDS             complement(2312..4618)
                     /locus_tag="PC512_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HDF2442742.1"
                     /translation="MINKGIRKIDSTAIVTGKPLYTEDLIMHKDVLTLKLLRSPHAHA
                     KIKNIDTSKAEKIPGVVGIYTYKDVPQVRYCVPGQTEPEASPYDRVLLEDTVRFIGDE
                     VALVAAEDEKTALKALKMIKVDYEVLKPVFDAREAEGNEVVIHPEKDIVEPYPFGLDA
                     KNNIVSKEFFEFGDVEAKLKESDFVVESSYKTQSQSHCMMETHRSYSYKDINDRIVVV
                     SSLQSPHNVKRILRKVLGIPSSKIRVIKPRIGGGFGGKNIAATDIFTAFVTMKTGRPA
                     KFVFTRSETFVGSNSRHEMFFDVKVGADKEGNLKAIELKSLNNTGAYGGNGVSVSSES
                     GHNTLPIYNDIDAVRFNARTVYTNRLPAGALRGYGATQGIFAIDSAIDELAHKIGMDP
                     LEFRIKNIIDRYTNGKAAEDEILSCELRQCIEKGKKLINWDDKYPCKDIGNNKVRAVG
                     MAVANHGSGIPRVDMATVTIRMDEDGTYKLLSGLADLGQGADTIQAQIAAEALNTTVD
                     RISIYTGDSDLCPYDTGAFASCTTTVTGNATIKTANKLKDILLSVAESKLGFKKEDLE
                     LGKDRVFVKNDNSKFVLLEELGRESVGGIGFASDDVPVVLEATESFGMLKKIKPFIAG
                     FAEIELDKNTGEYKVINFACVPDCGTVINPTLARIQVEGGVMMGIGFAMYEDPIFDKD
                     GRLLTDSFLQYKVPTKKEVGNILVDFAENFDPGGPYGAKSLGEIVIHTPAPAIANAIF
                     NATGVRLRELPMTFEKVYMGMKNNNKQL"
     gene            complement(4611..5405)
                     /locus_tag="PC512_003013"
     CDS             complement(4611..5405)
                     /locus_tag="PC512_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HDF2442743.1"
                     /translation="MVTIKEYSVPQSLEEAYKILISKKNNVILGGCGFIKLSNKNIGT
                     AIDLKDINLNYIKEDKKNILIGADTSLRSLEIDKTIKNYCSGILSSAVSNIVGVQFRQ
                     GARIGASVFSKYGFSDLIPALLVVGAKVRLYNKGILELSEFLDSELSRDILVEVILPK
                     KDAIAVFDSIRKCTGDFSVLNSAMLKENDTYKIAIGARPQKARLALEASNILNKEKDI
                     DKASIVASKELTYGSNMRASKEYRKDMASALVKRMYNAIEEGMYND"
     gene            complement(5512..6870)
                     /locus_tag="PC512_003014"
     CDS             complement(5512..6870)
                     /locus_tag="PC512_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine/pyrimidine permease"
                     /protein_id="HDF2442744.1"
                     /translation="MKAKSTSKFELDGIPPLKEAIPLGLQHLMAMVIGSCLPAILIAN
                     AAGLNHKMSTLLIQAALVFAGLSTLLQLYPIPLFKGFKLGGGIPVIMGATAMFIGAGV
                     SVASKYGLPVLFGSQIIAGIVIIIIGFGLKKIRFIFTPAVSGTIVACMGLGLFPIAIK
                     NLAGGMGNETFGNPINFIVGISVSLMILGLNKYGKGLFKDASILVSIIFGYILSLILG
                     IVNFSSIQEFTLVALPKPLAFGLDIRLEVVVMFSIIYLVEIADIMGACTLSAVGGLNR
                     QVTDEELSSAVLGNGVLSTIGALFSATPMGMFGQNSAIVSNTKVVSKFVLAIGGIGLF
                     LAGISPLLANLIRTIPPCVVGGATLVIFSTLTTSGLRLVSMDGFNQENSMILGLSMAS
                     GIGFMVAPQVLEKFPKFIETLLADSSVVSGAMVAIIIQALYMVKFPGNKSDKVEDKNK
                     SL"
     gene            complement(8218..9225)
                     /locus_tag="PC512_003015"
     CDS             complement(8218..9225)
                     /locus_tag="PC512_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442745.1"
                     /translation="MVMQVQEKILELLYTINEDVVSIKNDMSEVKQEINVLKEDMSEV
                     KQEMTVMKEDMSEVKQEINVLKGDMSEVKQEMTVMKEDMSEVKQEITVMKEDMSEVKQ
                     EINVLKVDMSEVKQEMTVMKEDMSEVRQEINIMKEDMSEVRQEINTMKEDMSEVRQEM
                     TVMKEDMSEVRQEMTVMKEDTSEVKQEINVMKKDMSEVRQEITVMKEDVSEVKSEVNF
                     MQNKINNINEDMNGIKDEVSIANEKLYGIEIKIDSLECEDKSMKEIQIEQNNILGSLL
                     HNSEINKATHDNIEHNIAYIKGDTNSIKEDIAEIRRDLNLVELATSKNWSDIVKLKSV
                     K"
     gene            complement(9455..10540)
                     /locus_tag="PC512_003016"
     CDS             complement(9455..10540)
                     /locus_tag="PC512_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HDF2442746.1"
                     /translation="MYNFLGKELKSPLIIGSGPLTYSAAGCKILSDAGAGAVVTKTIR
                     KERAINPAPHMVRNTANALLNNEKWTDFEPEQWIDFEIPQMKRDGTVCIASVGHTIEE
                     SSELVEKVANAGADFIELVSYDYRDLIPMLKDAKERVNIPVIVKLPPMIDEIGDFAKK
                     LEEAGADAITACDSVGPAFRIDIETGQPLLGGNGIGYLSGETIKPITLQRIYEIKKQV
                     NIPIIGLGGCVSGDDALEMIMAGADFVGICSVVILKGAQVISKIHDDLKSNLNRLGYN
                     TIENACGIVHNHMGDVNERLSFEFTYDEEKCTKCKMCERVCAYQARKLNDKMELNEEE
                     CRYCGLCISVCKPKALGRKISCSELNV"
     gene            complement(10576..11889)
                     /locus_tag="PC512_003017"
     CDS             complement(10576..11889)
                     /locus_tag="PC512_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HDF2442747.1"
                     /translation="MIAIKSKYLISSADEIYTNSAVVVENDIIKDILPNEEVEIKYKN
                     IEEIIDKSDAIIMPGFVNGHMHQYGVLSRGIPANVHFTDFEGFLNDYWWPFIENRIGL
                     KEVKATTKASAIELIESGVVAFCDTLEAPNTEEGTLIEQGKILEEIGMKAILSLESCE
                     RISFENGLRCLNENSNLIKWSRENSKLINGIMCTHTSFTCSDRFIKKAKEDTKKLNAP
                     MQFHLCESIYEPNYAEKHFGKKAVDYYNDLDILDETVLASQCVKVNDEEIDILKEKGV
                     KVVHMPLSNCEVGGGFSPVPKMIKKGIKVALGTDGYINDFFEVMRGAFLMHKSVEEDA
                     SVMPANLVFRMATEHGAYVLGLQNSGKIAVGNKADIIVMEDEFKTPVTLDNIFDQIVV
                     QGKKEFISNVYIDGRHILKEKQLVDLDKKAIVKEMKEVACEFWKF"
     gene            complement(11890..14181)
                     /locus_tag="PC512_003018"
     CDS             complement(11890..14181)
                     /locus_tag="PC512_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HDF2442748.1"
                     /translation="MVNKEVRKIDSEAIVTGKPIYTEDLIFHKDVLTIKLLRSPHAFA
                     KIKNIDIKNALKVKGVVNIFTYKDVPNYRYSMVGESYPEASPHDQLILEDVVRYVGDE
                     VAIIAAEDERAAIKAMKLIKVEYEVMTPILDARESEGNKILIHEEDDLFCPFDFGLDA
                     TKNIVSREKMGKGDVEKEFKESDVIVEHSYMTQSQAHCMMETHRAYTYIDTNGRLVVT
                     SANQSAYHMRRQVSKALGIPLSKVRVIKPRIGGGFGGKNIAVTEIYASFVTWMTKRPA
                     KLIYTREETFAMTNTRHQMFFDIKIGSDKEGNIKAIDMKALNNTGAYGDNGPSVCSES
                     GHNVLPTYNNVPAIKFDGRTVYTNLVPGGALRGYGATQGTFALDCAIDELAHKLNMDP
                     TEIKLKNIIKKQTEGGIMNFPIRSCALDECIIRGKKLIGWDEKYPVRDIGNNKVRAVG
                     MSVGTHGSGIANIDMAIVNMRMDEDGTYKLFSGSSDLGTGSDTILAQIAAKALNTSID
                     RISVYTGDTDMCPYDTGAYASCTTYVTGNATIKSAESLKQKILKVAQKKLDLPIDDLI
                     LYEDRVCYSEDVEKFVLLSELGKESVGGGNQEVLYSSESYGIQESAKPFLAGFAEIEL
                     DKTTGEFKVINYACSTDCGTVMNPALARIQVEGGVTQGIGLAMYEDPRHGSDGKLQTS
                     NLLQYKVPTKKDIGNIIVDFVDNYEPTGPYGAKSLGEIVIHTPAPAIANAIYNATGVR
                     IRELPITSEKVYMAMKKLNQGGK"
     gene            complement(14171..14965)
                     /locus_tag="PC512_003019"
     CDS             complement(14171..14965)
                     /locus_tag="PC512_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HDF2442749.1"
                     /translation="MITIKEYVVPKSLDEAYELLISRKNNIILGGCGFLKLGSKNIGS
                     AIDLKDLALDYINETDDSILIGADTSLRTLELNKVIKNYCNGVISNAVSNIVGVQFRS
                     GARVGASVFAKYGFSDLIPSLLVVDAKVKLYKKGVMNLADFLENELEKDILIEVILPK
                     KDAIGVFDSIRKCTGDFAVLNGAMLKEGSIYKIAIGARPRRAKIAYKASEILSLENDI
                     EKAGEVSSEELSFGSNIRGSKEYRKDMAKALVVRMYNSIGGECDGK"
     gene            complement(15004..15450)
                     /locus_tag="PC512_003020"
     CDS             complement(15004..15450)
                     /locus_tag="PC512_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster binding
                     domain-containing protein"
                     /protein_id="HDF2442750.1"
                     /translation="MIIKCTINNKEKELSIRPDDFLADTLRENGYVSVKKGCDTGSCG
                     LCTVMVNDKAVLSCNYLTARVEGQHITTLEGVLDEAKKFGDFLADEGADQCGFCAPGF
                     IMMVLAMKRELQNPTEEEVIDYVNGNLCRCTGYKGQLRAIHKYLNT"
     gene            complement(15522..16928)
                     /locus_tag="PC512_003021"
     CDS             complement(15522..16928)
                     /locus_tag="PC512_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2442751.1"
                     /translation="MMDILIKNAIIVTVNKEREVIFDGALVVKDNKIADIGNSKEIES
                     KYTDVKKIIDAKGKVLFPGFINTHNHLFQTLLKGLGDDMVLKDWLETMTFPAANYLEP
                     KDTYDAAMLGCIEGLRSGITTMVDYMYPHSKPGLCDGIIDAYKELGIRGILGRGCMNT
                     GAQFGVHPGIMQDVETVEKDVRRLFEKHHNTENGRIKIGVAPAAIWSNSQEMLEMLWR
                     VVKEYDDALFTVHISETPFDREAAKELHGQYDIDVLEKLGILGPNVLMVHCVYLTEKD
                     MELTKKYDMKVSHNTASNMYLSSGVAPVPEMLKKGITVSLGVDGAASNNSQDMLELMK
                     LTALQHKVNKCDPLAMSAEKVLELATIDGARAIGMEDEIGSLEIGKKADLLIFNPMLS
                     PKAIPMHNPVSTLVYSSSMKNIESVIVDGNIIMEDSKILTANEEKALKDAQDTAERLC
                     VRGTIKNRMEGHKWNSLY"
     gene            complement(16946..18316)
                     /gene="hydA"
                     /locus_tag="PC512_003022"
     CDS             complement(16946..18316)
                     /gene="hydA"
                     /locus_tag="PC512_003022"
                     /EC_number="3.5.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropyrimidinase"
                     /protein_id="HDF2442752.1"
                     /translation="MGTILRGGTIITSDKTYISDLRIEDEEIVEIGNNLEINGDKVID
                     ATGKIVIPGGIDTHTHFDMNAGSITTADNFETGTRAAIAGGTTTILDFAEANEGENLL
                     QGVEAYHKKASGNCYCDYGFHMTITCLNKDTFNHMEKLISDGIVSFKMYMAYDGMKVD
                     DGTIYRVLKKARDLGCIVGFHCENGDLLDVLIEENIQNGNLEPKYHPLTRPNIVEKES
                     VSRLADITKLSNSKSYVVHLSCRESLETVKMAREKNIDMIVETCPQYLLLEDNLYNKD
                     KFEGAKYVMSPPLRKKEDINYLWEGLSSGDIQTVGTDHCSFNFKGQKDLGIDDFSKIP
                     NGAPGVEHRLALLYTYGVLENRISANKFVEVTSTNAAKIFGMYPKKGEIAVGSDADIV
                     ILNINKEETISYKTQKQNVDYTPYEGFKVKCKVEDVFLRGNHVVQSCNVKEHPTGQYI
                     KRKITK"
     gene            complement(18449..>18697)
                     /locus_tag="PC512_003023"
     CDS             complement(18449..>18697)
                     /locus_tag="PC512_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HDF2442753.1"
                     /translation="EEDEFVQAAYKGLKEAGIDSEITQYSFCTNGSHYAGEAGIKTIG
                     FGPSKENLAHTIDEYIEQEQLFIGTEGYYGILKSVYGK"
BASE COUNT         5620 a         3637 c         1972 g         7468 t
ORIGIN      
        1 acacaaaatt tttgttttac acttccataa aatatctcta tttcactttc atattcttta
       61 atattttcta ctaattttat agctaaattt ttatattttt cattttcaac tttattaata
      121 aataatactc tttttccaga ataattttta aataatccat ttggatttaa tactatattt
      181 tttaagtttt caatacttac tgtagaacta ctattaatac tacttgtatc taaatttgct
      241 atttttttaa atatttctac tctatgtata ttctcttcat taatattcat tccaaatgat
      301 gttatatcta atatccctat ggtttttgta gttttatgat atactactgg ttctttagca
      361 ttccaacctt taagtttttt tctctttgag ccatctccct ctattaaaac taaatcaaat
      421 tggtctacaa tttcatccaa aatagaggaa tcaatactta ctaatttatt ttcattattt
      481 atataactgc cacagactgt tattccatga caaatagatg gaataacagt tccatctatt
      541 gtaataatta tattgtcata atcgtttggt acatatattt tagttgttgt tgtaaggaga
      601 actttcaatt tatctctata aaaatttgca aaatagttta taaacgaagt ttttcctcct
      661 gctccaacta cagttattat ttcattcttt tctattatat ttgatagttc cacactttca
      721 cctcttataa ccagttttct aatctcttaa ttattatagt tagacctttt tagtaaaagt
      781 gatttttgaa attccataaa ctcgaaagta aatagattct gttgtaaaca acaaggcgga
      841 tccaattcgc cgctaagctg taagcttacg ctatcagttt atcttttaaa tataattaag
      901 atattcttac tctctgtggt tgctttaata tttgaggatt attctgtaaa ttagataaat
      961 taactacttg tgattttttt agtatattaa gactcgcatt tacatctgca tttataatga
     1021 ttccaacact ggatttgtac tgtccacgcg ttattctttc ccctttaaag tcatattttt
     1081 taacattgtc cacattgata tcaggtagaa aatcatcagc aaaaaaatct gatttactag
     1141 tatagctttc ttcttgccta ataaaattga tattttttat tttacacaga tattctaatt
     1201 ttccttttat ctctccaaat gggattctta taaaatttct atatattttt ctctccatat
     1261 tatcactttt ttctaactta gcattatatc ctacaattaa atttccaata ttatttttta
     1321 cacaataatc aattatataa aaacaggttt tatttacata gtctttaact tgattatttc
     1381 tcttattcca aactttaaat tgttttcttg ttattgcagt tatattcttt tttaatttta
     1441 aggcttctat tttatcattc tgtttgtttg cccactgatt cacagatttt agcctttttc
     1501 catctatgat aaaactatca cctaaattgg taacacatgt acataaattt tctaaaccca
     1561 agtctatagc tagtgcattt ttttgatttg aaacttcctc tgattttggt atttcataac
     1621 aatactgaat ttcaaagaac ctagctttat gtttaggtat tattcttatt tctttaattt
     1681 ttttctctag tatattttgt ggaactttta tacttacttt cccatatagt tttttaaatg
     1741 ctggagacat aggtacattt aaaatcccat cttctttgat tcttatttga cctattatta
     1801 tgctaaaaaa tccttcttta tctaaatatt taggtgattt tatccctcta aagtcatatt
     1861 ttccttcttt ggctaattta attaatccaa aaaatgacct aaacgaactg tctacttctt
     1921 ttaatatttg ttgcgctata ttactattga gaagcttata gttctcattt tctttgcata
     1981 catgataatt agcttcatag ttaagatgtt ctccttgatt gaaataatgc tgtcttacat
     2041 tatatgtacc aacattatat aagttcttag ctaagaagca catctctcgt agagcttgat
     2101 attctttttt agttaagttt tttaattgtt gtctctgagt tccatagtgt atatttttta
     2161 ttctgtttga catgaactca cctcctttag aatatactct actagacatt atatacggta
     2221 tttttacaaa acaccatata taatgtccat ttaattactt tattttacaa aataatttaa
     2281 atttacttgc ttttatacac attattattt attataattg tttattatta tttttcatac
     2341 ccatataaac tttttcaaaa gtcataggaa gctctcttaa acgaactcct gtagcattaa
     2401 atattgcatt tgctatagct ggtgctggtg tatgtataac tatttctcct aatgatttag
     2461 caccataagg acctcctggg tcgaaattct cagcaaaatc taccaatata tttccaactt
     2521 ctttttttgt aggaacttta tactgtagga aactatctgt taataatcta ccatctttat
     2581 caaatatagg gtcttcatac attgcaaacc ctatacccat catcacacca ccttctactt
     2641 gtattctagc taaagttgga tttataactg ttccacaatc aggtacacat gcaaaattta
     2701 tgactttata ttcgcctgta tttttatcta attctatctc tgcaaatcct gctataaatg
     2761 gttttatttt tttcaacatg ccaaaagatt ctgttgcttc caaaactact ggtacatcat
     2821 cactagcaaa tcctattcct ccaacagatt ctctacccaa ttcctctaat agaacaaact
     2881 tgctattatc gtttttaaca aaaaccctgt cttttcccaa ctctaaatct tcttttttaa
     2941 atcctagctt tgactctgca actgaaagta atatatcttt taatttattt gctgtcttta
     3001 ttgttgcatt tcctgtaacc gttgtcgtac aagaagcaaa tgctcctgta tcatagggac
     3061 ataagtctga atcacctgta taaatagaaa ttctatctac agtagtattt aaagcttccg
     3121 cagcaatttg agcttgaatt gtatcagccc cttgacctaa gtcagcaaga ccagataata
     3181 gtttatatgt gccatcttca tccattctta tagtgactgt tgccatatct acacgcggta
     3241 taccagaacc atgatttgct actgccatac ctactgctct tactttgttg tttcctatat
     3301 ctttacatgg atatttatca tcccaattaa ttaatttctt gcccttttct atacattgtc
     3361 tcagctcaca acttaatatt tcgtcttcag ctgcttttcc attggtatac ctatctatta
     3421 tatttttaat tctaaattca agtggatcca ttccaatctt atgtgccaat tcatcaatag
     3481 cactatctat tgcaaatatt ccctgtgtag caccataccc tctaagtgct cctgctggta
     3541 acctattagt atatactgtt ctagcattaa atctaacagc atcaatatca ttatatattg
     3601 gtaaggtatt gtgtccagat tcggaagaaa cagagacacc attcccacca taagcacctg
     3661 tattgtttaa tgactttagc tctattgctt ttaaatttcc ttctttatct gcaccaactt
     3721 taacatcaaa aaacatttca tgtctactat tagaacctac aaaagtttca cttcttgtaa
     3781 atacaaattt tgctggtcta ccagttttca tagtaacaaa tgcagtaaat atatctgttg
     3841 ctgctatatt ctttcctcca aatccaccac ctattctagg tttaattact cttatttttg
     3901 aagatggtat acccaatact tttctaagta ttctctttac attgtgtggt gattgtaatg
     3961 atgaaactac aacaattcta tcatttatat ctttatatga atatgaccta tgagtttcca
     4021 tcatgcaatg cgattgactt tgggttttgt atgaagattc aaccacaaaa tcactttctt
     4081 taagcttagc ttcaacatct ccaaattcaa aaaattcttt tgatactata ttattttttg
     4141 catccaatcc aaaaggatat ggctctacta tgtctttttc tggatgtata acaacttcat
     4201 ttccttctgc ttctcttgca tcaaacacag gctttaaaac ctcataatct acctttatca
     4261 tttttaaggc tttaagtgcc gttttctcat cttcagcagc cactaaagct acttcatctc
     4321 caataaatct aactgtatct tcaagtaaaa ctctatcata aggtgatgct tctggttctg
     4381 tttgacctgg cacacaatat ctgacctgtg gtacatcttt atacgtataa atacccacaa
     4441 cccctggaat tttttcggct tttgatgtat ctatattctt tatcttagca tgagcatgtg
     4501 gacttctaag tagttttaat gtcaaaacat ctttatgcat aatgaggtct tcagtatata
     4561 gaggttttcc tgtgacaatt gctgtactat ctatctttct tatcccctta ttaatcatta
     4621 tacattccct cctcaatagc attatacatc cttttaacta atgcacttgc catatccttt
     4681 ctgtactctt tactagctct catattactt ccataagtaa gttccttact agcaacaata
     4741 gatgccttat ctatatcttt ttctttattt aatatattac tcgcttcaag tgctaatcta
     4801 gctttttgag gtcttgcccc aattgctatt ttgtaagtat cattttcttt tagcattgct
     4861 gaatttaata cagaaaaatc tcctgtgcat tttcttattg agtcaaaaac agctattgca
     4921 tctttttttg gtagtattac ttcgaccaat atatccctac ttaattcact atccaaaaac
     4981 tcacttaact ctagtattcc tttattgtat aatctcacct tcgctccaac aaccaaaagc
     5041 gctggtatta agtcagaaaa gccatacttt gaaaatacac ttgcaccaat tctagcccct
     5101 tgtctaaatt gaacaccaac tatattagaa acagcgcttg aaagtattcc actacagtaa
     5161 ttttttatag ttttatcaat ttctaaactt ctaagtgaag tatctgcacc tatcaaaata
     5221 ttttttttat cctcttttat ataatttaga tttatatctt ttaaatctat cgctgttcct
     5281 atatttttat tacttaattt tataaatcca catccaccta aaataacatt atttttttta
     5341 gaaattaaaa ttttatatgc ttcttctaaa ctctgtggaa ctgaatattc ctttatagta
     5401 accatcttat ccccccatca ttaacttatt aaaacacaaa agtttttaat aaatctttta
     5461 tttatattta taattgtagt atatttaatt cacatatatt aaacctttac attataaact
     5521 tttattttta tcctcaacct tatcactttt atttccagga aattttacca tatataaagc
     5581 ttgaattatt atggctacca ttgctcctga aactacactt gaatctgcaa gtaatgtctc
     5641 tataaatttt ggaaattttt caagaacttg aggagctacc atgaatccaa taccagaagc
     5701 catagaaaga cctaatatca tgctattttc ttgattaaat ccatccatac taacaagtct
     5761 taaaccagat gttgtaagag ttgaaaatat aacgagtgtt gctcctccaa ccacacaggg
     5821 aggaattgtt cttattaaat tagctaataa aggcgatatt cctgccaaaa ataatccaat
     5881 tcctccaata gctagtacaa atttacttac aacctttgta ttggaaacga ttgcagaatt
     5941 ttgtccaaac atccccattg gagttgcaga aaataatgca cctattgtag agagtactcc
     6001 atttcctaaa acagcagaag aaagttcttc atctgttact tgtctattaa gccctcctac
     6061 cgcagaaagt gtacaagcac ccattatatc agctatctca actaaatata ttattgaaaa
     6121 cattacaaca acttcaagtc ttatatctag cccaaaagca agtggttttg gaagtgcaac
     6181 caaagtaaac tcctgaattg aagaaaaatt tactataccc aaaattaatg ataaaatgta
     6241 tccaaaaatt atgctaacta atattgatgc atctttaaat aatccttttc catacttatt
     6301 taatcctaat atcataagag atacagatat tccaactata aaattaattg gattcccaaa
     6361 agtctcattg cccatacccc cagctaagtt ttttatagct attggaaaaa gtccaagacc
     6421 catacatgca actattgttc ctgatacagc tggagtaaat ataaatcgta tttttttaag
     6481 accaaaacca attataatta ttactatacc agctattatt tgagagccaa ataatactgg
     6541 tagtccatac ttacttgcaa cagatacccc agctcctata aacatagctg tagctcccat
     6601 tataactggt attcctcctc ctaatttaaa acctttaaac aaaggtattg gatataattg
     6661 taataaagtt gataatcctg caaaaactaa tgcggcttga atcaataatg ttgacatctt
     6721 atgattaagt ccagctgcat ttgcaatcaa tatcgctggt aaacaactac ctattaccat
     6781 tgccattaag tgttgtaacc ctaaaggtat tgcttccttt agtggtggta ttccgtctaa
     6841 ttcaaatttt gatgtacttt ttgctttcat aataaaaact cccgttacat aaaacttatt
     6901 gaattatata aatacttaaa aatctaatat attaaattaa tgatgttcat aaatatcaac
     6961 tatactccaa catatattta agtttttagt cttaaaaaac agatgcaata aatttaatta
     7021 ttaacaaata aacgtattct ttaattttgt atacattata taccatgctt tacaaatata
     7081 agagtattat agctatgaat ttttaatttt ttatagtaaa tttaattcaa tttaaatctt
     7141 tcaatcttaa tcattataag ttataagttt tcataagtat ttacatgttt caagttttaa
     7201 acatttacct ataaacgcta ctttatagat gtcacttcaa atccagtgac ctcatacttt
     7261 catatgagcg tagactattt cttcatcttc agcattacct gctaagagca acccgtttcc
     7321 actatcaatc gcttatagtg tactctctct cgagatagtc gtttgacctt cctatttcta
     7381 ggcttggcga ccaaatgtcc atttttaagt acttaggctc tcaccatata ccatcctcac
     7441 tattgtttct ggttttcacc acattcataa aagtttcttt ctatctttta ttgtagttgc
     7501 aaggctttag gatttactgg ttttaaagtt gtgtcctaca tagatttctc tatgtacggg
     7561 gccaaaagta caatttattt aacatacttt gctttacccc ctgtaaataa tattatttac
     7621 tctttcactg tttttgttat taaattaatt aaatatcaat taatctaagc ataaaataat
     7681 tatttaattt aaactcaaaa tatttatgaa tattttataa tataattctc ataagacaga
     7741 aaaacttaat aagctatgta tctcagttgt accaatgtac tctcctttac tatatttgta
     7801 tctgcaacat aaaatataca agtttctatc tatttataga tatatatatc tataagcaaa
     7861 atagtaatat tatttttaat agtaaaaatt ttattcatat tactatttat aatttttata
     7921 gagcaatttt agtgccaata tttgcataca tttgtatagt ataaaatttt tatgttctca
     7981 ttgataaaat tttacttatt tcaagcgttc tattagattt tatcatctaa attttaggtt
     8041 ttatttttat aaattaattg tatttacata aaaaaaaaga cctaaaaaca aatttttaac
     8101 ggtcttttct caatttttta ttttcatttc taaaatttat aataaatagt aagaacacta
     8161 taaattcttt tatataaaat tcttagtttg tggatgataa attagtgaat taaaatacta
     8221 ctttactgat tttagtttga caatatcact ccaattttta ctagtggcta actctactaa
     8281 atttaagtct cttcttattt cagctatatc ctcttttata gaattagtgt caccttttat
     8341 atatgctatg ttatgttcta tattatcatg agtagcttta tttatttcag aattatgtaa
     8401 taaacttcct aaaatattat tctgttctat ctgtatctct ttcattgatt tatcttcaca
     8461 ttctagacta tcaatcttaa tttcaattcc atataatttt tcatttgcta tggatacctc
     8521 gtccttaatt ccattcatat cttcattaat gttatttatt ttattttgca taaagtttac
     8581 ttctgattta acttcggaaa catcttcttt cattacagtt atttcttgtc tcacttctga
     8641 catgtctttt ttcattacat ttatctcttg ttttacctct gatgtatctt ctttcattac
     8701 agtcatttct tgtcttactt cggacatatc ttctttcatt acagtcattt cttgtcttac
     8761 ttccgacata tcctctttca ttgtatttat ctcttgtctt acctcagaca tatcctcttt
     8821 cattatattt atctcttgtc ttacctcgga catatcttct ttcattacag tcatttcctg
     8881 ttttacttcg gacatatcta cttttaatac atttatttcc tgttttactt cggacatatc
     8941 ttctttcatt acagttattt cttgttttac ttccgacata tcttctttca ttacagtcat
     9001 ttcttgtttt acttccgaca tatctccttt taatacattt atttcctgtt ttacttccga
     9061 catatcttct ttcattacag tcatttcttg ttttacttcc gacatatctt cttttaacac
     9121 atttatttct tgttttactt ccgacatatc attttttatg ctaactacat cttcatttat
     9181 agtatataat aactctaaaa tcttctcttg cacttgcatc accatcccta ttaattatta
     9241 taacatttta cacaaatgct atacaatgtt aacatatata tcagaattat taaaatttta
     9301 attaaacaaa attgattcac tttattactt caaaactaat taatatctaa aataactaca
     9361 aataaacaaa aataaggtca acaacaaaaa aggcttatct ctttgagata gcctttctta
     9421 tttttattta aaactttgtt ttttataaaa taatctatac attcagctct gaacatgaaa
     9481 tttttcttcc aagtgctttt ggtttacaaa ctgatataca aagtccacaa tatctacact
     9541 cttcttcatt caattccatc ttatcattca attttctcgc ttgatatgca caaactctct
     9601 cgcacatctt acatttagta catttttctt catcataagt aaactcaaag ctaagtcttt
     9661 cattaacatc tcccatatga ttatgtacta taccacaagc attttctata gtattatatc
     9721 ctaatctatt aagattagat tttaaatcat catgtatttt agatattact tgtgcgcctt
     9781 ttaaaattac tactgaacat ataccaacaa agtcagcacc tgccataatc atttctaagg
     9841 catcatctcc acttacacat ccacctaagc caattattgg tatattaact tgttttttta
     9901 tttcatatat tctctgtaaa gttattggct tgatagtttc tccacttaaa tatcctattc
     9961 catttccacc taataaaggt tgccctgttt ctatgtctat tctaaatgct ggtcctacag
    10021 aatcacaagc agttattgca tctgctcctg cttcttctaa ttttttagca aaatcgccta
    10081 tctcatctat cataggagga agtttaacta ttacaggtat atttactctt tcctttgcat
    10141 ctttaagcat tggtatcaaa tctctatagt cataagatac taattcaata aagtcagctc
    10201 ctgcatttgc aactttctct actaattcgc tactttcttc aattgtatga cctactgaag
    10261 ctatacagac agtcccatct cttttcattt gtggtatttc aaaatctatc cattgctctg
    10321 gctcaaaatc tgtccatttt tcattattta aaagagcatt agctgtattt ctaaccatat
    10381 gtggtgctgg atttatagct ctttcttttc ttatagtctt agtcacaact gcccctgctc
    10441 ctgcatcact taatatcttg catccagctg cactatatgt taatggtcct gaacctatta
    10501 taagtggtga ttttaattct ttacctaaaa aattatacat tatctgcttc cccttttcat
    10561 atatatttac attcgttaaa atttccaaaa ttcacaagca acttctttca tttctttaac
    10621 aatagctttt ttatctaaat caactaactg tttttctttt aaaatatgtc taccatctat
    10681 gtatacattt gatataaatt cttttttacc ctgaactact atctggtcaa atatattatc
    10741 aagagtcaca ggagttttaa attcatcttc cataactatt atatcagcct tattaccaac
    10801 tgctatttta ccagaatttt gaagtcctaa tacataagca ccatgctctg ttgccattct
    10861 aaatactaaa tttgctggca ttactgatgc atcttcttca actgatttat gcattaaaaa
    10921 tgcacctctc ataacttcaa aaaaatcatt tatatatccg tcagtaccca gtgccacttt
    10981 tatacctttt ttaatcattt ttggtactgg agaaaaacct ccacctactt cacagttgct
    11041 aagaggcata tgaaccactt ttacaccttt ttcttttaat atatctattt cttcatcatt
    11101 tacttttaca cactgagatg ctaatacagt ttcatccaat atatctaaat cattatagta
    11161 gtcaactgct tttttgccaa aatgtttttc agcatagttt ggctcatata tactctcaca
    11221 taaatgaaat tgcattggtg catttaattt ttttgtatct tctttagctt tcttaataaa
    11281 tctatcagaa catgtgaagc ttgtatgtgt acacattatt ccatttatta atttactatt
    11341 ttctctactc cactttatta aattagaatt ttcatttaaa catctaagtc cattttcaaa
    11401 gcttattctt tcacaacttt ctaaggataa aatcgctttc atgcctattt cttctagtat
    11461 ttttccttgc tcaattaaag ttccttcttc tgtatttgga gcttctaggg tatcacaaaa
    11521 agctaccaca ccagattcta taagttctat tgctgatgct ttagttgttg ccttcacttc
    11581 tttcaatcca attctatttt ctataaatgg ccaccaatag tcatttaaga aaccttcaaa
    11641 gtcggtaaaa tgtacatttg ccggtattcc cctagaaaga actccatatt gatgcatatg
    11701 accattgacg aatcctggca ttattatagc atctgattta tctattattt cttcaatatt
    11761 tttatatttt atttcaactt cttcatttgg caatatatct tttataatgt cattttctac
    11821 tacaacagca gaatttgtat atatttcatc agcagaagat attaagtatt tacttttaat
    11881 agcaatcatt tatttacctc cctgatttaa ttttttcatg gccatataaa ctttctcaga
    11941 agttatagga agttctctta tacgaactcc tgtggcattg tatattgcat ttgctattgc
    12001 tggtgcaggt gtatgaataa ctatctctcc taaagattta gctccatatg gacctgttgg
    12061 ctcataatta tctacaaaat caacaattat gtttcctata tctttttttg ttggaacttt
    12121 gtattgtaat agattagaag tttgaagctt tccatcagaa ccatgtctag ggtcttcata
    12181 cattgcaagc cctatacctt gagttacacc accttcaact tgtattctag caagtgcagg
    12241 attcataact gtaccacaat ctgtagaaca agcataattt attactttaa actcccctgt
    12301 tgttttatct aactctattt cagcaaatcc tgctaagaat ggtttagcac tctcttgtat
    12361 accataagat tcagatgaat ataaaacttc ttgatttcca ccaccaacag attcttttcc
    12421 taattcactt aacaaaacaa acttctctac atcttcacta taacaaactc tgtcttcata
    12481 tagtattaaa tcatctattg gtaaatcgag tttcttctgt gctactttta atatcttttg
    12541 ttttaaactt tcagcagatt ttattgtagc atttccagtt acataagtag tacaagaagc
    12601 gtatgcacca gtatcatatg gacacatatc tgtatctcct gtataaacgg aaattctatc
    12661 aatagatgta ttcaatgctt ttgcagctat ttgtgcaagt attgtgtcag aaccagttcc
    12721 taagtctgaa gacccagaaa acaacttata agttccatct tcatccatcc tcatatttac
    12781 tattgccatg tctatgttgg ctataccaga accatgagtt cccacagaca ttccaacagc
    12841 cctcacctta ttgtttccaa tatccctaac agggtacttt tcatcccatc caataagttt
    12901 tttacctcta attatacatt catcaagtgc acaacttctt attggaaaat tcattattcc
    12961 gccttcagtt tgttttttta taatattctt taactttatt tctgttgggt ccatattaag
    13021 tttatgcgct aattcatcaa ttgcacaatc aagtgcaaat gtaccttgtg ttgctccata
    13081 tcctcttaat gctcctcctg gaactaaatt agtatataca gttctcccat caaattttat
    13141 tgcaggtaca ttattatatg ttggaagtac attatgacct gattcagagc aaactgaagg
    13201 tccattatcg ccataagcgc ctgtattgtt caatgctttc atatctatag cttttatgtt
    13261 tccttcttta tctgacccaa tttttatatc aaaaaacatc tgatgtctag tattagtcat
    13321 tgcaaaagtt tcttctctag tataaattag ttttgctggt ctttttgtca tccaagttac
    13381 aaatgatgca tatatctctg ttacagctat gttttttcca ccaaaacctc cacctattct
    13441 tggttttatt actctcactt ttgaaagagg tattcccagt gctttagaaa cctgtcttct
    13501 catatgataa gctgattggt ttgcagaagt tactactaat ctgccattcg tatctatata
    13561 cgtataagct ctatgagttt ccatcataca atgggcttgt gattgagtca tataagaatg
    13621 ttctactatt acatcacttt ctttaaactc tttttctaca tcccctttac ccattttttc
    13681 tctcgataca atattttttg tagcatccaa tccaaaatca aatggacaaa acaaatcatc
    13741 ttcttcatgg attaaaattt tatttccttc cgattctctt gcatccaata taggagtcat
    13801 tacttcatat tcaactttta taagtttcat agctttaata gcagcccttt catcttcagc
    13861 ggctattata gcaacttcat ctcctacata tctaactacg tcttcaagta ttaattggtc
    13921 atgaggtgat gcttctggat atgactctcc aaccattgaa tatctataat ttggaacatc
    13981 tttgtaagtg aatatgttta ctacaccttt tacctttaat gcatttttta tatctatgtt
    14041 ttttatcttc gcaaaagcat gtggacttct aagaagctta attgttaaaa catctttatg
    14101 aaaaattaaa tcttctgtat atattggttt tccagtaaca atggcttcac tatctatttt
    14161 tcttacctct ttatttacca tcacactcac ctccaatact attatacatt ctcactacta
    14221 aggcttttgc catatctttt ctgtattctt tacttcctct tatattactt ccaaatgaaa
    14281 gttcttcact tgatacttca ccagcttttt ctatatcatt ttctaaactt aatatttcac
    14341 ttgctttata ggcaattttt gctcttcttg gtctagcgcc tatcgcaatt ttataaatac
    14401 ttccttcttt taacattgct ccatttaata ctgcaaaatc acctgtacat tttcttatag
    14461 aatcaaatac acctatagca tcttttttag gtaatataac ttctattaat atatcttttt
    14521 caagctcatt ttctaaaaaa tcagctaagt tcataacccc ttttttatat aacttaacct
    14581 ttgcatctac cactagtaat gaaggtatta aatctgaaaa tccatactta gcaaatacgc
    14641 tagctcctac tctagctcca cttctaaatt gaactcctac tatattagaa acagcgtttg
    14701 aaattacccc attacagtaa tttttaataa ccttatttaa ttctaaagtt cttaaacttg
    14761 tatctgctcc aattaatatg ctatcatcag tttcatttat ataatctaaa gctaagtctt
    14821 ttaaatctat tgctgaacca atatttttac tacctagttt taaaaatcca catcctccaa
    14881 gtattatgtt gttttttctt gatattagca gttcataagc ttcatctaaa ctttttggaa
    14941 ctacatattc ctttatagtt atcatactct ctccccatat caacttaatt ttcacttaaa
    15001 agtctaagtg tttaaatatt tatgtattgc tcttaattga cctttatatc ctgtacatct
    15061 acaaaggtta ccatttacat aatctataac ttcttcttct gttggatttt gaagctctct
    15121 tttcattgcc aagaccatca ttataaatcc aggagcacaa aatccacact ggtcagcccc
    15181 ttcgtctgca agaaaatctc caaacttctt tgcttcatcc aagacaccct caagtgttgt
    15241 aatatgctga ccttctactc tagcagtaag ataattacat gaaagcacgg ccttgtcatt
    15301 taccatcact gtacataacc cacatgagcc tgtatcacac ccttttttaa cacttacata
    15361 tccattttct cttaatgtat ctgctaaaaa atcatctggt cttatactta attctttttc
    15421 tttattattt atggtacatt tgataatcaa ataaatcacc tcaaaactca tatttttaag
    15481 ctaaagtttt actatacttt tttatgaata aattacattt attaataaag gctattccat
    15541 ttatgacctt ccattctatt ttttatagtt cctcttacac aaagtctctc agctgtatct
    15601 tgagcatctt ttaatgcttt ctcttcatta gctgtcaata tttttgaatc ttccattatt
    15661 atatttccat ctactataac actctctata tttttcatac tagaagaata tactaatgta
    15721 gataccggat tatgcatagg tatcgctttt ggtgaaagca ttggattaaa tattaataag
    15781 tctgcttttt tacctatctc caatgaacct atctcatctt ccattccaat agctcttgct
    15841 ccatctatag ttgccaactc aagaactttt tctgctgaca ttgctaatgg gtcacactta
    15901 ttaactttat gttgaagtgc tgttaatttc ataagttcaa gcatatcttg agagttatta
    15961 ctagcggctc catctactcc taaactaact gttattcctt ttttaagcat ttctggcact
    16021 ggtgcaacac ctgaagataa gtacatatta cttgctgtat tatgagacac tttcatatcg
    16081 tattttttag taagttccat atctttttca gttagataca cacaatgtac cataagcaca
    16141 tttggtccaa gtattcctaa tttttctaaa acatctatgt catattgccc atgcaattct
    16201 tttgctgctt ctctatcaaa aggagtctct gatatatgta ctgtaaataa agcatcatca
    16261 tattctttta ctactctcca tagcatttca agcatttctt gagaatttga ccatattgct
    16321 gcaggagcta ctcctatttt gattcttcca ttttctgtat tatggtgttt ttcaaacaat
    16381 cttcttacat ctttttcaac cgtttctaca tcttgcatta ttccaggatg aactccaaat
    16441 tgagctcctg tattcataca tcctcttcca agtattcctc ttattcctaa ttctttataa
    16501 gcatctatta ttccatcaca aagacctggc ttactatgag gatacatgta gtcaaccatt
    16561 gttgttatac cacttctaag tccttcaata catccaagca ttgcagcatc ataagtatct
    16621 tttggctcta aatagttagc tgctggaaat gtcatagttt ctaaccagtc tttaagtacc
    16681 atatcatctc ccaatccttt taataaagtt tggaataaat gattatgtgt atttataaaa
    16741 cctgggaata aaactttacc tttagcatct ataatttttt taacatcagt atatttactt
    16801 tctatctctt tagaatttcc aatatcagca atcttgttat cttttactac taatgcccca
    16861 tcaaaaataa cttctctctc tttattcaca gttactatta tggcattctt aataagtata
    16921 tccatcattc ttatttcccc ccgcattatt tagtaatttt tcttttaata tattgacctg
    16981 ttggatgttc tttaacatta caactttgta ctacatgatt tcctctcaaa aatacatctt
    17041 caactttaca tttaacctta aatccttcat atggagtata atctacattt tgtttttgag
    17101 ttttataact aattgtttct tctttattga tatttaaaat gactatatct gcatcacttc
    17161 ctacagctat ctcacctttt ttaggataca ttccaaatat ttttgcagca ttcgtagaag
    17221 taacttccac aaacttattt gcacttattc tattttctaa gactccatat gtatataaaa
    17281 gtgctaacct atgttcaaca ccaggtgctc catttggtat cttactaaaa tcatcaattc
    17341 ccaagtcttt ttgcccctta aaattaaatg aacagtgatc tgtgccaact gtttgaatat
    17401 ctccactaga caatccttcc caaaggtaat ttatgtcttc tttttttctt aaaggaggag
    17461 acattacata cttagcaccc tcaaatttat ccttattata taaattgtct tctaataata
    17521 gatactgtgg gcatgtttct actatcatat ctatattttt ttctctagcc atttttacag
    17581 tttcaagtga ctccctacaa cttaagtgga ctacatagga ttttgaatta gataatttag
    17641 ttatatcagc aagtcttgaa acagactctt tctcaactat gttaggtctt gtaagtggat
    17701 gatattttgg ctccaaatta ccattttgta tattttcttc tatcaataca tctagtaaat
    17761 ccccattttc acaatgaaat ccaactatac aacctaaatc ccttgctttc tttaaaaccc
    17821 tgtatattgt tccatcatct actttcatgc catcatatgc catatacatc ttaaaagata
    17881 ctatcccatc cgaaataagt ttttccatat gattaaatgt atctttattt aaacatgtaa
    17941 ttgtcatatg aaaaccataa tcacaataac aatttccact tgctttttta tgatatgctt
    18001 ctacaccttg cagtaggttt tccccctcat tggcttctgc aaaatctagt attgtagtag
    18061 ttcctccagc tatagctgct cttgttcctg tttcaaaatt atctgcagtt gtaatagaac
    18121 ctgcattcat atcaaaatga gtatgtgtgt ctattccacc aggaattaca attttacctg
    18181 tagcatcaat aaccttatca ccatttattt ctaagttatt tcctatttca actatctctt
    18241 catcttctat ccttaaatca cttatataag tcttatcaga ggtaattata gttccacctc
    18301 ttagtattgt tcccatatat acctcctaac ttttaagctt taaagtattt tctaagtatt
    18361 gtaaaacttt atttaaaatt gtattttcta aaggtgctat attcagcacc tctagactat
    18421 atttaaataa tttattgtga actaaatatt attttccgta tacagatttt aatattccat
    18481 agtaaccttc tgttcctata aataactgtt cttgctctat atactcatct attgtgtgag
    18541 caagattttc cttagaagga ccaaatccta tagtttttat tccagcttca cctgcatagt
    18601 gacttccatt cgtacagaat gagtattgag ttatttctga atctattcca gcttctttta
    18661 atcccttata tgctgcttga acaaattcat cttcttc
//
LOCUS       DAMJVG010000083        18557 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.083, whole genome shotgun sequence.
ACCESSION   DAMJVG010000083 DAMJVG010000000
VERSION     DAMJVG010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18557)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18557)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18557
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.083"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(219..899)
                     /locus_tag="PC512_003024"
     CDS             complement(219..899)
                     /locus_tag="PC512_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2442754.1"
                     /translation="MQTKILIIDGDKDNCQKLKGFLEEKGISIDLAYNCEEAIGKIFS
                     NKYDLIFLEIILSDGDGWTLCKKIRNVTTCPIVYMTYINEDQSILNALNSGGDDYLIK
                     PLNLEILYAKVKAILRRMNSYVNNNENNTKLEEYNRTSGVIKLEDKIIKLTPTENKLL
                     NFFIENPEKTLTTKEIYEHVWMNEYLEDNYSVVVAVNGLRKKIEKDYKNPQKIITIRG
                     AGYYFNKE"
     gene            complement(949..2964)
                     /locus_tag="PC512_003025"
     CDS             complement(949..2964)
                     /locus_tag="PC512_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HDF2442755.1"
                     /translation="MKKYNILKGTLIVLIVSLLAITGLNLLYKYDNKYTYKSIRASNG
                     ILTIDNDTFTKGKLVFLIDDWEFYNHKIFKPNDFTEQDIKPEYVFIGQYPDFSMRKGT
                     QSPYGNATYRMRIKNEGKDKLLSLELPEIFSASEVWINGEMVSKLGDVGTEKYRPKIK
                     NSVVSFIAKKNTEIIINVSNFSHYYSGLYYPPALGETKDISNMMFYRLLFYSIICFTT
                     FAIAIFSLSVWFLSNKSKIYLYFGCMCVFFAIHVSYPFVHLLGLPLVSFTYAVEDLSY
                     FMVVLCIICINGSISKIEENKVYRFLILPLGITMSIISIVIPIILLPYDMYFVNIYGK
                     LIDIYKYIVFIYILMSSLVSIYKKTCSEHISSYILVSVNTVFGISILFDAVTSNRFEP
                     IFTGWQTEYCGFVIVILFSVMMINRNRIIIKENEKLTRNLEHEVEVRTNELTTLLNER
                     KRFLADVAHDLKAPVSAIQAFIDLIKVGNIHVDEETRTYLYAINQKSNEVQNRVRSLQ
                     EFTSQDKSIGISEKICLNNFIKEIYENNLPDTQACGVNFETYVLEKKIYAKINKEMLT
                     RAFENLIYNALTFTPFDGKIILSMDKEDGFAIIKISDNGKGIPPENIPKVFDRFFTER
                     DNNEPKGQGLGLYIVKSIIREHGGEIFVDSELGKGTVFTIKLSLCFL"
     gene            complement(3036..3713)
                     /locus_tag="PC512_003026"
     CDS             complement(3036..3713)
                     /locus_tag="PC512_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2442756.1"
                     /translation="MYNLLVVDDDVDILNINQIYFSNIGFNVYTSETAKDAMDIVESI
                     VLDCIILDISLPDIDGYKMCNDIKEKVNIPIIFLSNYEHEEEKVRGFLAGGDDYITKP
                     YSLKELELRIYARMRQYKNITSVPNVLKFSALVINVNSRKVTFDGESIDLTTMEFEIL
                     LFLAENKEQVFSKIEIYNQVWKMPDIGDQHTVQVHIAQMRKKINSLSREHQYIQTVWG
                     KGYKFVP"
     regulatory      complement(4293..4376)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            complement(4609..5451)
                     /locus_tag="PC512_003027"
     CDS             complement(4609..5451)
                     /locus_tag="PC512_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF2442757.1"
                     /translation="MFKKKIGVLLASTMLVGALAVGCSSNSGGSGDSGDSSKVSVSGS
                     TSIGPLMETIGEKFQEKNQGVSVEVQQIGSSGGIKNAIEGTSEIGMSSRDLKDEEKSA
                     GLKETKIAIDGIALITNTANSVKNLTMDQVKGIYTGKITNWKEVGGNDAPIVIVSREE
                     GSGTRDGFQEIVGFDSEELTKDAQISDGSGNIKTTVEGNENAIGYISFGYVDEKVNSL
                     KINDVEATDANVIANKYPISRPFILVNKEDGLSEKGKALIDYILSDEGQALVSEKGFI
                     KVNQ"
     gene            complement(5703..7487)
                     /gene="pepF"
                     /locus_tag="PC512_003028"
     CDS             complement(5703..7487)
                     /gene="pepF"
                     /locus_tag="PC512_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HDF2442758.1"
                     /translation="MGTDRSTIEEKYKWKIDKMYSSKEEIEKDISKVKNLIQEVKEYK
                     GKLSESKENLYKVLNISENASRIVQNLYVYTHMKQHEDTRINDNQGRATKTEMLSTDL
                     GVATSYIVPEILAIEENKLSEYLKDEKLSFYTKYIKDILRDKPHTLSEREEEILAATS
                     ELSTIPENVYDMLAYADMEFPEIEDEEGNKVKLSHSNYSLFIKSKNSRVRKDAFEGEF
                     STYEKYKNTFASTLYGGIKSEIFYAKTRKYNSAIEASLFSDDVSLDVYNNLISAIDKS
                     IPNLNKYVELKKKFLGLNEIHMYDLYVPLTDKFDMDIPYDKAQDIILEALKPLGEEYL
                     KVIKSAFDEGWIDVYDNEGKKGGAYSWGSYDSHPYILMSYKNDLNSLFTLVHELGHSV
                     HSHYSRTSQPFLYSDYKIFVAEVASTLNELLLINYLLENSKSKDETIYLLNYYLEQFR
                     TTVHRQTMFAEFEKIVHQRVESGEPLTADEFTNIYYKLNEKYYGKSAIVDKQIGIEWA
                     RIPHFYSNFYVYKYATGFSAASALSQQILSEGSTAVDRYINFLKSGGSEYPLEQLKSA
                     GVDMTKKESIEEALNVFAELVNKLEKEL"
     gene            complement(7553..8218)
                     /locus_tag="PC512_003029"
     CDS             complement(7553..8218)
                     /locus_tag="PC512_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HDF2442759.1"
                     /translation="MIDIGSKEIAIRLLLALIIGGIIGLEREKIRQFAGFRTHILIAI
                     GSCIVSITSIQLFFDYNLYTNADPARMPAQVLSGIGFLGAGAILKNKGGVKGLTTAAG
                     MWATACIGIAVGYGYYELAILGGLFVMIALFVLRIINTFLFSQEKNVLILKLSNLDSI
                     PFLYDKFEKNQLIVRNMEIECRNEEYWKVNFFVSYAKRIHLHDVMKEINMIEGVINVD
                     YLD"
     gene            complement(8369..8530)
                     /locus_tag="PC512_003030"
     CDS             complement(8369..8530)
                     /locus_tag="PC512_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartyl-phosphate phosphatase Spo0E family
                     protein"
                     /protein_id="HDF2442760.1"
                     /translation="MANNELEALKNEIEAVREEINTYIEYPEIFQEELVESSKKIDIL
                     INKYMYLSK"
     gene            complement(8608..9117)
                     /locus_tag="PC512_003031"
     CDS             complement(8608..9117)
                     /locus_tag="PC512_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HDF2442761.1"
                     /translation="MKTRKMTFLGLMIGYSLALYVLETYIPNPLIVIFPGAKLGLSNI
                     ITLISLMLLGVKDTVIIVTIRVILSSIFAGPLSYLLFSIGGAYLSLLFMYLASKIKDL
                     SLIGISIIGAIGHNIGQLIVASLIIENILAIGYLPFMLMASLVTGMFVGLVSRYTIPK
                     LKHFYSKFY"
     gene            9323..9541
                     /locus_tag="PC512_003032"
     CDS             9323..9541
                     /locus_tag="PC512_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HDF2442762.1"
                     /translation="MTVYDLKIGEKGFINSIDGDIKLSKRLLALGCINSTEIEVKKVA
                     PLGDPIIIRFRGFDLAIRKSDAKNISLQ"
     gene            9559..11505
                     /gene="feoB"
                     /locus_tag="PC512_003033"
     CDS             9559..11505
                     /gene="feoB"
                     /locus_tag="PC512_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HDF2442763.1"
                     /translation="MINVALLGNPNVGKTTVFNLLTGSNQYVGNWPGVTIEKKEGFLG
                     KEIKVVDLPGIYAMDTFSNEEKVSKSYLENEDVDVIVNVVDASNLSRNLYLTTQLMQF
                     NKPIVILLNMLDIAESKGVNIDAKKLSEELGVIVVPIIAKKKNGVDRIEEEIKGATQK
                     AFIYQKNFGSETETYKKLESILSRCTKTTYTQKKSISDKIDNIVLNPILAYPIFIGVL
                     FLLFKFTFDWVGGPLQEGFASLIEAYISAPVSDMLSNSSPWFKSLIVDGIIGGVGGTL
                     PFFPLIFTLFFGISLFEDSGYMSRTAFLMDKVMRKVGLSGKAFIPIVMGMGCSSPAIM
                     ATRTLESEKDRRVTALIAPLMTCGAKLPIYALFVAIFFPHNAALVTTSLYLVGIVMAI
                     VVALFLNKTAFKTEAEPFILELPEYRIPTIDALIKNTWNKSKGFLIRVVTVMFAMSVV
                     IWGLSSFNVFGYTEDINVSFLATLGHIISPIFKPLGFDDWRTSVAILSGLGAKEIVVN
                     SLNILYGNLTVVLPTIFNGVTAYTFLIFTALYTPCIAALATMKKEYGNKMMFTSFAYQ
                     FILAWIMAFIVKSIGGVLFMGNSIMEALIGGIIIVLALFILFNKFKSTKNGNVCSGCS
                     ICSGCPSANSCSSKEDSNKKNNAH"
     gene            complement(11684..12739)
                     /locus_tag="PC512_003034"
     CDS             complement(11684..12739)
                     /locus_tag="PC512_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDF2442764.1"
                     /translation="MTIQDYMLETPVRMREIISNADSLFNEVKRTNLKKIIITGSGTS
                     YHSGVQVQPYLQNLLDIDVVKMYPFMITEDTFKFDNENTLVVGVSQGGSSYSTYNAMK
                     LAEDKGCKIASMAGCKNALIDEISDYILTVNCGEEKSGAKTKGYYCTKLNLMLLGLQI
                     AREKGIISSEKYNEEINKILDAINRFEAVYKLSKQWIERNKEKLVNSKEIRIIGHSDI
                     YGDTLEAALKLLETMRIPVTGYEFEEFIHGIYNAINSDSTIFILDTGKEPRVTKMIDV
                     LSGWTENVFAIGRDVTENDKNLKIDITDNPYYQTFNFIVPIQLICGEIPTLRGVDPSV
                     PKDTRFHMKLGSKKLNK"
     gene            complement(12787..13587)
                     /locus_tag="PC512_003035"
     CDS             complement(12787..13587)
                     /locus_tag="PC512_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDF2442765.1"
                     /translation="MNKLTKKELRSMFWRSFALQGAFNYERMQNLGYCYSMLPAIKKL
                     YNKKENQAKAIERHLEIFNTTTVVVPAILGITAAMEEENANNPEFDESSISAVKTALM
                     GPLAGIGDSLFWGTFRIIAAGVGVSLAKEGNIFGPLLFLLLYNIPAFALRIFGLKYGY
                     QVGVNSLERIQREGLMEKIMSMATTVGLFVVGGMVATMLSITTPLKFNLNGAEVILQD
                     ILDKIIPNMLPLTFAFVIYYMLKRKVSVTKLTIGTIVTGIALHAIGLL"
     gene            complement(13580..14371)
                     /locus_tag="PC512_003036"
     CDS             complement(13580..14371)
                     /locus_tag="PC512_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2442766.1"
                     /translation="MLVQATMLAIIAGVGILDGRIFGQSMLDRPIVTGMLVGLVLGDI
                     KSGIMIGAQLELIWMGIAGIGAATPPDVVTGGVLGTAFAILSGNGAEVALAVAVPVAV
                     LAQSLGVLVRIINSYFSQKAVFYAKQADFKKVTIMMWLPVILFFLSTSVPTFLAIMIG
                     ADKVTALINAIPKVILDGLGVAGTLLPAVGFALLMDMLLSKKMSVFFFIGFLLASYGG
                     LDITAIALFGVCVAFVLNFYINNKENNQNPQLAINTLTEGEIDFE"
     gene            complement(14411..14833)
                     /locus_tag="PC512_003037"
     CDS             complement(14411..14833)
                     /locus_tag="PC512_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HDF2442767.1"
                     /translation="MKKFLIATHGELSRELVDTSKLIIGSLTNIEYFCMTTDKSADDA
                     EKEIRSILSNNKDSEEFVVLTDVFGGSVANICTNLLLQGFKFELLTGVNLPMLLSILL
                     LVEEDTKLIVKSGLEEAKNGIVYVNELLENQNKIKNVM"
     gene            complement(14849..15328)
                     /locus_tag="PC512_003038"
     CDS             complement(14849..15328)
                     /locus_tag="PC512_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2442768.1"
                     /translation="MVSLMRIDDRLIHGQVAYGWATSLGINVILVANDEAKNDQMKAM
                     SLNLAKPSNVTLYIRGVEESGEIVEKFASSKKSNVLVLVKNTKDALVVAKNSGGVLKE
                     INVGGLRYEEGKKKLTDLVAVDDDDINNFKQIGDLGIDIEFRMLPRDKKKQLSDLIK"
     gene            complement(15460..18216)
                     /locus_tag="PC512_003039"
     CDS             complement(15460..18216)
                     /locus_tag="PC512_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2442769.1"
                     /translation="MRDEILSFVNECVLFNSFDELKKESGIITEDIVKKFNLSRTQSS
                     RLLNDLVKSDNLIKINSRPVIFLPKNKINDVVGPTKKSIYENLDELKNECKLLKQETV
                     FNSIIGYDNSLKEVIEQIKTAVLYPNGGLTIMLTGESGVGKTFLAKIIYKYSVSSNVL
                     EKNSPYNVLNCAQYYNNLELLSSLLFGHVKGAYTGANESRAGLIEQSDGGVLFLDEVH
                     RLNSEGQEKLFTFMDTGTFSRIGENGVIRKARVRLIFATTESLSEFLQTFLRRIPINI
                     YVPNIEERGTIEKRKIVEHFIYEESKVLGLPIEITQITLNAILKIKFKGNIGECKNVI
                     KYACGRAYAKNQRRNGNIFVTLQDLPRNLYIENVDIFQFQSGKSKSIIFSPKQFSIEM
                     SNGRNKRNIIYQSFIKCLDYFDRLEKNEITKEKFSKKSSNLMIRLMDNLVFSNNDENN
                     NVLMELIISIMQDIFRNLEVNNNIKYDGNNVLAFSSYLYLKDESYQLSDEYKALENKL
                     LIYLKKESYKEYSIISKISTLITNRLDMYLNNVDTIIMIIFIKSTIIRMKFNQVNATI
                     IAHGYATASSMANVCNRMLGKNIFTAIDMPIDATIADVSKQMSRYLEGDRIKNGLIVL
                     FDMGSLNLIYEDLKNKINSPMLFIDQISTISALEVGNLLMQGKNIEEIAEIMDEETKP
                     NIQLYYPQKNKEYAIISSCFTGIGIAIKIQHLLSESLIGIVDVKIIPYDYDSLVSMGD
                     KEPVFEMYDVMAIVGTANPNVNGVDFILLEDIISGKGEDDVFRIFSRVVENEKIKNIN
                     DSIVKNFSLIRVIDSLTILDSKKIIERIEEGINAIENIQKKKLSNDKKISLYVHLSCM
                     IERLVRQTEIEEYTDMDLLIKNHHSEVKLIKNAFSVLEKSYSVQIPISEIGYIYNIIY
                     GLPQ"
BASE COUNT         6089 a         3165 c         2037 g         7266 t
ORIGIN      
        1 tagatataca atttatccat cttttcaaat ataatctata aaataatagt tccattacgc
       61 atttttttat ataataaaac tgactgtaat ttaactggca aagtctagaa gaataggatt
      121 tatcaattaa attacagtca gctattttat aataatttag tttagatatc gttagtattt
      181 cacatttata acaattatta atgatattaa tatatttatt attccttatt aaaataatat
      241 cctgctcctc ttattgttat aattttctga ggatttttat aatctttctc tattttcttt
      301 cttaatccat tcactgcaac taccacacta tagttatcct ctaagtattc attcatccat
      361 acatgttcat atatctcttt agtagtcaaa gtcttttcag gattctctat aaaaaagttt
      421 aacaacttat tttctgttgg agtcaatttt attattttat cttctaactt tattactcca
      481 ctagttctat tatattcctc taattttgta ttattttcat tattatttac atatgagttc
      541 attcttctta aaatagcttt tacttttgcg tataatattt ctaaatttag aggctttatt
      601 aagtaatcgt ctccaccaga atttaaagca tttaaaatgc tttggtcttc atttatataa
      661 gtcatataaa caattggaca agtagttaca tttctaattt ttttacaaag agtccatcca
      721 tcaccatcac ttagaattat ttctaaaaat attaaatcat atttattgct aaatattttt
      781 ccaatagctt cttcacaatt atatgctaaa tctatactta ttcctttttc ctccagaaat
      841 ccttttagct tctggcaatt atccttgtct ccatctatta tcaatatctt agtttgcatt
      901 ataatcactc ccaaatatca ttattctttt atattaaata agctattatt ataaaaaaca
      961 tagacttaat tttattgtaa aaacagttcc ttttcctagt tctgaatcta caaatatttc
     1021 tccaccatgc tctcttataa tggatttgac aatatatagc cctaaccctt gcccttttgg
     1081 ctcattattg tctctttctg taaagaatct gtcaaatacc tttggtatat tttctggagg
     1141 tatacctttt ccattatcag aaattttaat aattgcaaat ccatcttctt tatccattga
     1201 taaaattatc tttccatcaa atggagtaaa ggtcaaagca ttataaatta aattctcaaa
     1261 tgctcttgta agcatctctt tatttatctt tgcatatatt tttttctcca atacataagt
     1321 ttcaaagttt acaccacatg cttgtgtatc tggcaaatta ttttcatata tctctttaat
     1381 aaaattattc agacatattt tttcactaat accaatgctt ttatcttgtg atgtaaattc
     1441 ttgcaaacta cgtactctat tttgtacttc atttgacttt tgatttatag cataaagata
     1501 ggttcttgtc tcttcatcta catgaatatt accaaccttt atcaaatcta taaatgcttg
     1561 tatagccgaa acaggtgcct ttaaatcatg tgctacatct gccaagaatc ttttacgttc
     1621 atttaacaat gttgtaagtt cattagttct cacttcaact tcatgttcaa gattccttgt
     1681 aagtttttca ttctctttta ttattattct attcctgttt atcatcataa cagaaaataa
     1741 aataacaatt acaaacccac aatattctgt ttgccaccct gtaaatatag gctcaaatct
     1801 attactcgta actgcatcaa ataatatgct aattccaaaa acagtgttta ctgaaactaa
     1861 aatataagaa cttatatgct cagagcatgt ctttttatat attgaaacca gcgaagacat
     1921 taatatatat ataaatacaa tatatttata tatgtctatt aacttcccat atatgttgac
     1981 aaagtacata tcatatggaa gaagaataat tggtatcact atagatatga tactcattgt
     2041 aattcctaat ggtaaaatta aaaatctata cactttattt tcttctattt tggatatact
     2101 tccatttata caaataatac ataaaactac cataaaatat gacaaatctt caaccgcata
     2161 tgtaaagctt accaaaggca gtcctaacaa atgtacaaag ggataggata catggatggc
     2221 aaagaaaaca cacatacatc caaaatataa gtaaatttta cttttgtttg aaagaaacca
     2281 tacagacaat gaaaatatag ctattgcaaa agttgtgaag caaattatac tataaaaaag
     2341 taatcgataa aacatcatat tacttatgtc ctttgtttct cctaatgcag gcggataata
     2401 caaaccacta taataatgtg aaaaattcga tacattgatt ataatttctg tatttttctt
     2461 tgcaataaaa cttactactg aatttttaat tttgggtcta tatttttctg ttcctacatc
     2521 tcctaattta gaaaccattt ctccatttat ccatacttca cttgcggaaa aaatctcagg
     2581 aagctctaaa cttagtagct tatccttgcc ttcatttttt attctcatac gataagtagc
     2641 attcccatat ggtgactgag tcccttttct catagaaaaa tctggatatt gacctataaa
     2701 aacatattct ggttttatat cttgctctgt aaaatcattc ggtttaaata ttttatgatt
     2761 ataaaactcc cagtcatcta tcaaaaagac aagtttacct ttagtgaaag tatcattatc
     2821 tatagttaaa attccattac ttgctctaat agacttatat gtatatttat tatcatattt
     2881 atacagaaga tttaatcctg ttattgccag cagagagact atcaatacaa tgagagttcc
     2941 ttttagtata ttatactttt tcattgtatc aaccacatct ctttcatagt agtattaaat
     3001 aaaacaagaa ctatttatta attacagtat ctcacttatg gtacaaactt atatcctttt
     3061 ccccatacgg tttgaatgta ttgatgctcc ctgcttaaag aattaatttt ttttctcatc
     3121 tgtgcaatat gaacctgcac tgtatgttga tctccaatat caggcatttt ccaaacttgg
     3181 ttatatatct ctatctttga aaatacttgt tctttgttct cagctagaaa caataatatt
     3241 tcaaattcca tagtagttaa atctatactt tctccatcaa aagttacttt tcttgaattt
     3301 acatttatta ctaacgctga aaactttaac acattaggaa ctgatgtaat atttttgtac
     3361 tgcctcatac gagcatatat tctaagttca agttctttta aactataagg ttttgttata
     3421 taatcatccc ccccagctaa aaatccccga actttttctt cttcatgctc ataattagat
     3481 aaaaatatta taggtatgtt aaccttttct tttatatcat tgcacatttt atatccatct
     3541 atatctggca atgaaatatc caaaattata cagtctaaaa ctatactctc tactatatcc
     3601 atagcatctt tagcagtctc tgatgtatat acattaaaac ctatattaga aaaataaatt
     3661 tgatttatgt ttaaaatatc aacatcatca tctacaacca gtaaattata cattacacca
     3721 ctccattcaa aggtatttta attataattc caagttttat agttattaca aattataatg
     3781 ttttattttc atatataact ggtattatta ttttataata tctttacaaa ctagactata
     3841 atacttaagt atttttgaat aattcttgaa tattgtatta aacattaaga ttcattatta
     3901 aatactaatt aaagtctccg attgttggag aatggagctt aaagtcattt tcacgtataa
     3961 atttattatt tttctagaaa cttgtctatt ggctagtttg agtattgatt tatatgattt
     4021 atatggttat aatataaaat aaattgtatt attttggtaa atatattgtt acaaaaggtt
     4081 tatattctgc atctcaatgt ttataaaaac tttattttct tattataata ctattattct
     4141 tttaaaaaaa tttccctttt ccaacaaatg gctactttaa aagccaaaat tttacctatc
     4201 aataaaaatc ttaacgacta atactcttat tttcaaattt tgcaacattt ttgttaattt
     4261 taaaacaaaa aaagactatg caatataaaa attatattca tagccggttg caccactaac
     4321 tccatatatc tctagatgcc caataataag atatacttct cagtttctaa aatattttta
     4381 ttaaaaatct tttatatatt ttcataaatt tcttttttat tctaacattg taatattatt
     4441 ttgtcaatat ttccatattc ttagagataa gatactaaaa tacctatttt atctaaagat
     4501 atttatattt ctacattcaa taatagacaa taccctgcaa gttaaagcat catttttatg
     4561 agcttatctc acagggtatt atatgtttac tttatattat aactcttgtt attgattaac
     4621 tttaataaat cctttttctg aaacaagtgc ttgtccttca tcacttaata tataatctat
     4681 taaagcttta cctttttctg acaaaccatc ttctttatta actaatataa atggtcttga
     4741 tattggatat ttattagcta ttacatttgc atcagttgct tcaacatcat ttatttttaa
     4801 actatttact ttctcatcaa catatccaaa tgatatatat cctatagcat tttcatttcc
     4861 ttcaactgta gtttttatat ttcctgaacc atcacttatt tgtgcatctt tagttagttc
     4921 ttctgaatca aaccctacaa tttcttggaa tccatctcta gttcctgaac cttcttctct
     4981 tgatactatt actattggtg catcatttcc tcctacttct ttccagttag taatctttcc
     5041 tgtatatata cctttaactt ggtccattgt cagatttttt actgagtttg cagtattagt
     5101 tatcaatgct ataccatcta ttgctatttt agtttccttt aatccagcac ttttttcttc
     5161 atcttttaaa tctcttgaac tcattcctat ttcagatgtt ccttctatag cattttttat
     5221 acctccagaa gaaccaatct gttgtacttc tacactaaca ccttgatttt tttcttgaaa
     5281 cttttctccg atagtttcca taagaggacc tattgaagtt gaacctgaaa cagaaacttt
     5341 gcttgaatct cctgaatcac ctgaacctcc tgagttagaa ctacatccta ctgctaaagc
     5401 tccaactaac attgtactag ctaaaagaac gcctattttc tttttaaaca ttttacttac
     5461 ccccgcttat attttaattt tttgttgtca tttttctata ttttaataat acagattctt
     5521 tgttaaatga atattagagc agggttaagt aaatgtaaat attgttaaat acatgtaaaa
     5581 acttaatttt atatgattta ttcttaatta gattaacttt ttaaagttac tttaggcaga
     5641 tataaacata atacaactca tattatcaga agtcttcatt gaagctatca acctatcaca
     5701 tcctataatt ctttttctag tttattaact aattcagcaa atacatttaa ggcttcctct
     5761 atagattctt ttttcgtcat atctacacca gcagatttta attgttctag tgggtattct
     5821 gaccctccac tttttaagaa gtttatatat ctatctactg cagtacttcc ttctgaaagt
     5881 atctgttgac ttaaagcact tgcagcagaa aaccctgtgg catacttata tacatagaag
     5941 tttgaataaa aatgaggtat tctcgcccat tctattccta tttgtttatc tactattgca
     6001 gattttccgt aatacttttc atttaatttg tagtatatat tagtaaattc atcagcagta
     6061 agtggttctc cactctctac cctttgatgt acaatttttt caaattcagc aaacatagtt
     6121 tgtctatgaa ctgtagttct aaattgttct aaataataat ttaataagta tatagtttca
     6181 tccttagact tagaattttc taataaataa tttataagaa gtaattcatt taatgtagat
     6241 gcaacttctg caacgaatat cttatagtcc gaatataaaa atggttgact tgttcttgaa
     6301 taatgactgt gaacagagtg ccctaattca tgaactaaag tgaatagaga attaaggtca
     6361 tttttatagc tcattaatat ataaggatgt gaatcataac ttccccaaga ataagctcct
     6421 ccttttttac cttcattatc atatacatca atccaccctt catcaaaagc actttttatg
     6481 accttcaagt attcttctcc taaaggttta agtgcctcta atatgatatc ctgtgcttta
     6541 tcatatggta tatccatgtc aaatttatct gtcaaaggaa catacaaatc atacatgtgt
     6601 atttcattca atcctaaaaa tttcttttta agctcaacat atttatttag attaggaata
     6661 cttttatcta tagctgatat aagattattg taaacatcta aacttacatc atctgaaaat
     6721 aaagacgctt ctattgctga attatacttt ctagtttttg cgtaaaatat ctctgatttt
     6781 attccaccat aaagcgttga ggcaaatgta tttttatatt tctcatatgt tgaaaattca
     6841 ccttcaaaag cgtcttttct aactctacta ttcttacttt ttataaataa agagtagttt
     6901 gaatgagaaa gcttaacctt attcccctcc tcatcttcta tctcaggaaa ttccatatct
     6961 gcatatgcta acatatcgta tacattttct ggaattgtcg ataattctga tgtagctgca
     7021 agtatttctt cctctcgttc actcaaagta tgtggtttat ctctcaatat atcctttata
     7081 tattttgtat aaaaggatag cttctcatct tttaagtatt cacttaactt attctcttct
     7141 atcgccagta tttctggaac tatataagaa gtagccacac ctaaatcagt agataacatt
     7201 tctgtcttag tggctcttcc ttgattatca ttaattctag tatcttcatg ttgtttcata
     7261 tgagtatata catataaatt ttgaacaatc ctagatgcat tttcagagat atttaatact
     7321 ttatataagt tctccttact ctcagaaagc ttccctttat attcttttac ttcttggata
     7381 agatttttta ctttacttat gtctttttca atttcctctt tactggagta catcttatct
     7441 atcttccatt tgtacttttc ttctattgta cttctatcag ttcccatatc atacacctct
     7501 attttaattt gttttatatt ttattcactt tacaaaatat attgtatata ttttagtcca
     7561 aataatctac atttattact ccttctatca tatttatttc tttcataaca tcgtgtaagt
     7621 gtattctctt agcataagat acaaaaaaat taaccttcca gtattcttca ttacgacatt
     7681 ctatttccat atttcttacg ataagttgat ttttttcaaa tttatcatat aaaaaaggta
     7741 tagagtccaa attgcttaat tttaatatca atacattctt ttcttggcta aataaaaacg
     7801 tattgattat cctaagcaca aataatgcta tcattacaaa taatccacct agaattgcca
     7861 attcataata accatatcca actgctatac caatacatgc agttgcccac atcccagcag
     7921 ctgtagtaag cccttttacc ccacctttat tttttaaaat tgctcctgca cctaaaaaac
     7981 caattccaga taatacttga gcaggcattc ttgctgggtc agcatttgta tacaaattat
     8041 aatcaaagaa taattgaatc gaagttattg aaacaataca agaacctatt gcaattagta
     8101 tatgtgtcct aaatcctgca aactgtctta ttttttctct ctctaagcct attattcctc
     8161 ctattattag tgctaatagt aaccttattg ctatctcctt acttcctata tcaatcataa
     8221 tataaaaccc tcctgactta attacaactt atgtcctaca gataatttac acatcagaaa
     8281 tactatttta tatcttaata ttattattaa tatatgtaaa atatagccat ctgttaattt
     8341 ttgatacaaa aaaacccaca actgtgggct atttgcttag gtacatgtat ttatttatta
     8401 atatatctat tttcttactt gattctacta actcttcttg aaatatttct ggatattcta
     8461 tgtatgtatt tatctcttcc ctaactgctt caatctcatt ttttaacgct tctaattcat
     8521 tgttcgccat aataatcacc actattacaa atttgtatat ttttatatac attttatcaa
     8581 acaatattat attttgtcaa tattatgtca ataaaactta ctataaaaat gctttaattt
     8641 aggtattgta tacctggata ctaagcctac aaacatacca gttactaatg atgccattaa
     8701 cataaatggt aagtacccta tagcaagtat attttctatg attaaacttg caactattaa
     8761 ttgacctata ttatgcccta ttgcacctat aatgcttatc cctattagtg ataaatcttt
     8821 tattttactc gctaaataca taaataaaag actcagataa gctcctccta tactaaatag
     8881 tagatatgat aaagggcctg caaatattga tgacaaaatt accctgatag taacaattat
     8941 aacagtatct ttgacaccta acaacattaa tgaaattaaa gttataatat tgctcaaacc
     9001 caattttgcc cctggaaata taactataag aggatttggt atatatgtct ctaatacata
     9061 taaagctaaa ctatacccta tcataagacc taaaaatgtc atttttctag ttttcattaa
     9121 gttaactcct ccaaatttta tctatcatct tacattataa tacaaaatat ataaaaacac
     9181 ctaatttaga ctaaaatatt tttaatctat ttagaataaa tattagttat ttcaatgtgc
     9241 aattacctct ataaatcttg actttttgta tcatacttgt tacaatttta atgataatga
     9301 atttcattag gaggtgttaa taatgactgt ttacgattta aaaataggag aaaaaggatt
     9361 tattaatagt atagatggag atattaaatt atctaaaaga ttgcttgcac ttggatgtat
     9421 aaatagtact gaaatagaag ttaaaaaggt tgccccactt ggagacccaa ttataattag
     9481 atttagaggc tttgaccttg cgattagaaa atctgatgct aaaaatattt ctttacaata
     9541 atagaggagg agctacccgt gattaatgta gcattattag gaaacccaaa tgtcggtaaa
     9601 actactgttt ttaatctact tacaggttca aatcaatatg taggtaactg gcctggtgtt
     9661 actatagaaa aaaaagaagg atttcttgga aaagagataa aggttgtcga tttacctggt
     9721 atatatgcaa tggatacttt ctcaaatgaa gaaaaggttt ctaaatcata tttagaaaat
     9781 gaagatgttg atgtaatagt aaatgtagtt gatgcttcta atttatcaag aaacctttac
     9841 ttaacaactc aacttatgca atttaacaag cctatagtta tattgcttaa tatgttagac
     9901 attgcagaat ctaaaggagt taatatagat gccaaaaaat taagtgaaga acttggagta
     9961 attgttgttc caattatagc aaaaaagaaa aatggtgttg ataggataga agaagagatt
    10021 aagggagcta cgcaaaaagc ttttatatat cagaaaaact ttggaagtga aacagaaaca
    10081 tataaaaaat tagaatccat tttatcgaga tgtacaaaaa ctacatatac acaaaagaaa
    10141 tctatcagtg ataagataga caatatagtc ttgaatccta tattagcata tccgatattt
    10201 attggtgtat tgttcctctt atttaaattt acctttgact gggtcggagg accactacaa
    10261 gagggatttg ctagtcttat agaggcttat atttctgcac ctgttagtga tatgttatct
    10321 aactctagcc catggtttaa atcacttata gttgatggaa taattggagg tgttggtggt
    10381 actttaccat tcttcccttt aatatttaca ttattctttg gtatatcgtt gtttgaagat
    10441 agtggataca tgtcaagaac agcattttta atggataaag ttatgagaaa ggttggtcta
    10501 tctggtaaag cttttatacc tatagttatg ggtatgggat gttcttctcc agctataatg
    10561 gcaactagaa cattggaaag cgaaaaagat agaagagtta cagctcttat tgcaccactt
    10621 atgacttgtg gagcaaagct acctatatat gcactatttg tagctatatt ctttccacat
    10681 aatgctgctt tagtaactac atcactgtat ttggtgggta tagttatggc aattgtagtt
    10741 gcattattct taaataaaac agcctttaaa acagaggctg aaccatttat attagaatta
    10801 ccagaatata gaatccctac tatagatgca cttattaaaa atacttggaa taaatcaaaa
    10861 ggtttcttga taagagttgt tactgtcatg tttgcaatgt cagtcgtaat ttggggactt
    10921 tcttcattca atgtttttgg atatacagaa gatataaatg taagcttctt ggctactcta
    10981 ggtcatatta tatctcctat attcaaacct cttggttttg atgattggag aacttcagtt
    11041 gctattttaa gtggtcttgg agcaaaagaa atcgtagtaa actctttaaa tatactatat
    11101 ggtaatctaa ctgttgtctt accaacaata tttaatggag ttactgcata tacattcttg
    11161 atatttactg ctttatatac tccatgtata gctgcacttg caactatgaa aaaagaatat
    11221 ggcaataaaa tgatgtttac atcatttgca tatcaattta tactagcatg gataatggct
    11281 tttatagtta aaagtatagg tggagtacta tttatgggta attcaataat ggaagctttg
    11341 ataggtggaa taattatagt ccttgcactc tttattctgt ttaataaatt caagtctaca
    11401 aaaaacggaa atgtctgtag tggatgttct atttgttctg gatgtccaag tgctaattct
    11461 tgctcaagta aggaagacag caataaaaaa aataatgcac actaatatat aaatatttta
    11521 gtttaaaata agataaaagt gggtgtctca aaattaactt tttagttcat gaggcactct
    11581 tttttatata aaatcaaata tattttcatc atttcaacag taaaaaagag cttatctagt
    11641 aaaaaagagg cttatctcta ttttgagaca acctcttttt ttgttactta ttcagtttct
    11701 tgctacctaa cttcatgtgg aacctagtat cttttggaac acttgggtct acacctctta
    11761 atgtaggtat ttccccacat attagttgta taggtactat aaaattaaat gtttgatagt
    11821 aaggattatc tgtgatatca atctttaaat ttttatcatt ttctgtaaca tctctaccta
    11881 tagcaaatac attttccgtc caaccagaaa gtacatcaat catcttagtt actctaggtt
    11941 cttttcctgt atctagtata aatatagtag aatcactatt tatagcatta tatataccat
    12001 gtataaactc ttcaaactca tacccagtta caggtattct cattgtttcc aataatttta
    12061 atgctgcttc taatgtatct ccatatatat cagagtgacc tattattctt atttctttag
    12121 aattaactaa cttttctttg tttctttcaa tccattgttt agagagctta tacactgctt
    12181 caaatctatt aattgcgtct aatatcttat ttatttcctc attgtacttt tcactagata
    12241 ttataccttt ttctctagct atttgaagac ctaataacat taagtttaac tttgtacaat
    12301 aatatccttt tgttttagct ccagattttt cttcaccaca atttactgtt aatatataat
    12361 cagaaatctc atctattaaa gcattcttac aacctgccat agatgctatt ttacagccct
    12421 tatcttcagc taacttcata gcgttgtatg tagaataact actcccacct tgagatacac
    12481 ctactactag ggtattttca ttatcaaact tgaatgtatc ttcagttatc ataaatggat
    12541 acattttcac aacatctata tctaataaat tttgtaaata tggttgcacc tgcactcctg
    12601 agtgatagct agtacctgaa cctgttatta taatcttttt tagatttgtt ctcttaactt
    12661 cattaaataa gctatctgca ttagatataa tttctctcat tctaactggt gtttctaaca
    12721 tataatcttg tattgtcatt ttatacacct tccttatcta tatattcaat aaattataat
    12781 taatttctat aacaaaccta tagcatgtaa agcgattcct gttactatag tgcctatagt
    12841 taattttgtt acacttacct ttctctttaa catgtagtat attacaaatg caaaggttaa
    12901 aggtaacata ttaggtatta ttttatctag tatatcttgt aaaattactt ctgcaccatt
    12961 taagttgaat ttcagaggag tagttatact caacatagtt gcaaccattc ctcctacaac
    13021 gaataaacca acagttgtag ccatagacat tattttctcc ataagtccct ctctttgtat
    13081 tctttcaaga gaatttaccc ctacttgata accatactta agtccaaata ttctaagggc
    13141 aaatgctggt atattgtata atagtaagaa taatagtggt ccaaagatat taccttcttt
    13201 tgcaagtgat actcctactc ctgctgctat aatcctaaat gttccccaga ataatgaatc
    13261 accaattcct gcaagaggtc ccataagagc tgttttaaca gcactaattg aactttcatc
    13321 aaattctgga ttattagcat tctcttcttc catagcggct gttataccta atatagcagg
    13381 aactaccact gtcgttgtat taaaaatctc caaatgcctt tctattgctt ttgcttgatt
    13441 ttctttctta ttgtatagct tctttattgc aggtaacatt gaataacagt aacctaagtt
    13501 ttgcattctt tcgtaattaa atgcaccttg aagagcaaat gaacgccaaa acatacttct
    13561 taattctttt tttgttaatt tattcaaagt caatctctcc ttccgttaaa gtattgattg
    13621 ctaattgagg attttgatta ttttctttgt tattgatata aaagtttagt acaaatgcta
    13681 cacatactcc aaataaagct atagcagtta tatctaatcc accataagat gctaacaaaa
    13741 accctataaa gaaaaataca gacatctttt ttgaaagtaa catatccata agcaatgcaa
    13801 aacctactgc tggcaacaat gttcctgcaa cacccaatcc gtctaatata actttaggta
    13861 ttgcatttat taatgctgta actttatcag caccaatcat aattgctaaa aaggttggaa
    13921 ctgatgtact taaaaagaat aatattactg gcaaccacat cattatggta actttcttaa
    13981 aatcagcctg tttagcatag aaaactgcct tttgagaaaa gtacgaattt attattctaa
    14041 ctaatactcc aagagattgt gctaagactg ctactggtac tgctactgct aaagcaactt
    14101 ctgcaccatt acctgataat atagcaaaag ctgtacctaa tacacctcct gttactacat
    14161 ctggaggagt agctgcacct attcctgcaa ttcccatcca aattaattca agctgtgcac
    14221 caatcataat tcctgatttt atgtctccta aaactaatcc tactaacata cctgtaacta
    14281 ttggcctatc aagcatagat tgaccaaata tacgcccatc tagtatacca actcctgcta
    14341 taatagctaa catagtagct tgtactaaca tattgaacct ccattttaac ttagtttaat
    14401 ttacattaaa ttacattaca tttttgattt tgttttgatt ttctaataac tcatttacat
    14461 aaacaattcc attttttgct tcctctaatc ctgatttaac tattagtttt gtatcctcct
    14521 caactaataa aagtatagat aaaagcattg gtaaatttac tcctgtcaat aattcaaatt
    14581 tgaacccttg taaaagtaag tttgtacata tgtttgccac acttccacca aacacatctg
    14641 ttaagacaac aaattcttca ctatctttat tatttgataa tatacttcta atttctttct
    14701 cagcatcatc tgctgattta tccgttgtca tacaaaaata ctcaatatta gttaatgaac
    14761 caattattaa tttacttgtg tcaacaagct ctctggacaa ttctccatgt gttgcaatta
    14821 gaaatttttt cattctcttt ctcctaaatt attttattaa atctgatagt tgtttctttt
    14881 tgtctctagg taacattcta aattctatat caatccctaa atcacctatt tgtttaaagt
    14941 tatttatatc atcatcatca acagcaacta aatctgtaag tttcttcttc ccttcctcat
    15001 atcttaatcc tcctacattt atttctttta atactcctcc tgaattttta gctacaacta
    15061 aagcatcttt ggtatttttt actaacacta atacattgct tttctttgaa gaagcaaatt
    15121 tttctactat ttctccagat tcctctaccc cccttatata taaagttaca ttgctaggtt
    15181 tcgctaagtt cagtgacata gctttcattt ggtcattttt tgcttcatca tttgcaacta
    15241 gtattacatt tatacctagt gatgttgccc atccatatgc aacctgacca tgtatcaatc
    15301 tgtcatcaat tctcatcaaa gataccattt tccccaaatc ctccatcata cattaaaatt
    15361 tttattgttt atactctcat ttatctataa aagcaaaaag tatgccaaat actggcatac
    15421 ttttttaaat ttcattcact tattttgtaa tcttgtattt tactgtggta gaccatagat
    15481 aatattataa atatatccta tctctgaaat tggtatttgc acactataac tcttttctag
    15541 cacactaaat gcatttttta ttagttttac ttcactatga tggtttttga ttaacaaatc
    15601 catatcagta tactcttcaa tttcagtttg tctaactaat ctttcaatca tacaacttaa
    15661 gtgaacatat aaagaaatct ttttatcatt tgaaagtttt ttcttttgaa tattttctat
    15721 agcattaatt ccttcttcta ttctctctat tatctttttt gaatctaaaa tagttagact
    15781 atctattact ctaattaatg aaaaattctt tacaatagaa tcatttatgt tctttatttt
    15841 ttcattttct actactctgc taaatattct aaaaacatca tcttctcctt ttcctgatat
    15901 tatatcctct aataatataa aatctacccc attcacattt ggattggcag ttcctactat
    15961 agccatcaca tcatacattt caaaaactgg ttctttatct cccatagaaa caagactatc
    16021 ataatcataa ggtattattt tgacatcaac tattccaatt aaactttcgg aaagtagatg
    16081 ttggattttt atagcaatac ctatccctgt aaaacaagat gatattatag catattcttt
    16141 atttttttga ggataataca attgtatatt aggtttagtt tcttcatcca taatttctgc
    16201 aatctcttca atgtttttac cttgcattaa taaatttcct acttctagtg cagaaatagt
    16261 ggatatttgg tctataaata acattgggct atttatctta ttctttaaat cttcatatat
    16321 aagattaaga gagcccatat caaataatac aattaaacca ttctttatcc tatctccctc
    16381 tagatatcta gacatttgtt ttgatacatc agcaatagta gcatctatag gcatatcaat
    16441 agctgtaaat atatttttac ccaacatccg attacataca ttcgccatac tactggcagt
    16501 agcatatcca tgtgctataa tagtcgcatt aacttgatta aatttcattc ttataattgt
    16561 tgatttaata aatataatca ttatgattgt atctacatta ttaagataca tatccaatct
    16621 attcgttatt aatgttgata ttttacttat tatagagtat tctttgtaac tctctttttt
    16681 taaatatatt agtaatttat tttctaaagc tttatactca tcagacaatt gataagattc
    16741 gtccttcaaa taaagataag acgaaaatgc caatacatta ttcccatcat attttatatt
    16801 gttattaact tctaaatttc taaatatatc ctgcattatc gatattataa gctccataag
    16861 tacgttatta ttttcatcat tatttgaaaa gactaaattg tccattagtc taatcattag
    16921 attagaactc tttttactaa atttttcctt tgttatttca tttttttcta gtctatcaaa
    16981 gtaatctaaa cattttatga aactttgata gattatattt cttttatttc ttccatttga
    17041 catttcaata ctaaattgtt taggagaaaa gataatgctt ttgcttttac cactttggaa
    17101 ttgaaatata tctacatttt ctatataaag atttctagga aggtcttgaa gagtaacaaa
    17161 aatatttcca tttcttcttt gattttttgc ataagctcgt ccacatgcat attttattac
    17221 atttttacat tcacctatat tccccttgaa ttttatcttt aaaatcgcat ttaatgtaat
    17281 ttgagttatc tctataggca aaccaagtac cttactttct tcataaataa aatgttctac
    17341 aatctttctt ttttcaatag tccctctttc ttctatattg ggaacataaa tatttatggg
    17401 tattcttctt aaaaaggttt gtaaaaattc agatagactt tctgttgtag caaatattaa
    17461 tcttacccta gcttttctaa ttactccatt ctctccaatc ctagaaaacg tacctgtatc
    17521 cataaatgta aataactttt cctgaccttc actatttaat ctatggactt catctaaaaa
    17581 taaaacacca ccatctgatt gttctattag acctgctcta gattcatttg ctccagtata
    17641 tgctcctttt acatgcccaa ataatagact agacaataac tccaaattat tataatactg
    17701 cgcacagttt aacacattgt atggagaatt tttttctaat acattactgc ttacactata
    17761 tttgtatatt atcttggcta aaaaagtttt tcctactcca ctttcacctg tcagcattat
    17821 tgtaagtccg ccatttggat aaagtacagc ggtttttatt tgttcgatta cttcttttaa
    17881 gctattatca tatcctatga tactattaaa cacagtctct tgctttaata atttacactc
    17941 atttttaagt tcatctaaat tttcataaat actttttttt gtaggtccta ctacatcatt
    18001 tattttattt ttaggtaaaa aaataacagg tctactgttt atctttataa gattatcaga
    18061 ttttactaaa tcatttaata atctacttga ttgagttcta cttaaattaa acttttttac
    18121 tatatcttct gttattatgc cactttcttt tttaagttca tcaaagctgt taaataatac
    18181 acattcattt acaaaactta aaatttcatc cctcatgttc aacctccaat acaaatatca
    18241 ataatactat aatattagta tatcatttat atatttatga aaaagataat tatattccta
    18301 tcttgattct cttttgtaag gttgtaaaat caaacttttt ataagtataa aatctagatt
    18361 ttttaacata atctcaaggt tcttatcttt ccatatatct gacatagaat ttatataaga
    18421 atatatttat tgtatttatt ataataaaaa gtaaaacatt ataggtattt taaaacttat
    18481 tagcgaagaa aatatttgta acttttatta ccttatgaat attatttcaa atttaaaaag
    18541 gctataaata aatttat
//
LOCUS       DAMJVG010000084        17330 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.085, whole genome shotgun sequence.
ACCESSION   DAMJVG010000084 DAMJVG010000000
VERSION     DAMJVG010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17330)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17330)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17330
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.085"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            63..809
                     /locus_tag="PC512_003040"
     CDS             63..809
                     /locus_tag="PC512_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HDF2442770.1"
                     /translation="MKIENLSIDDIKRGYIFNDDLNCYSCIKCTKTYEVGEIYKIGNR
                     FFEASKAIELHMELEHSDYLEQLLNSDSKYNTLTENQKQLFQLFISDLPDKEIAKQVG
                     VSTSTIRHQKFIFREKAKQAKLYLALYESVFEDKSNKSSTIIPIHEHARMVDERYVVT
                     EEERKHILDTSFESMNPLKLKVFSSKEKKKVVILSKILEQFERGKKYSEKEVNQILES
                     IYDDFATIRRYLIEYGFMSRNKECTKYWLT"
     gene            870..1544
                     /locus_tag="PC512_003041"
     CDS             870..1544
                     /locus_tag="PC512_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase"
                     /protein_id="HDF2442771.1"
                     /translation="MNDELKSILYNKGVDIVRFVDISEFPINQTQGFSKAILFCIGLS
                     KKFITDIYNNLPTDSDEFLEKEEKVEELADWISKYIQNKGYRAYSQSEKNNLEHGYFE
                     KAYINPEMQSGISPLPHKTIANISGIGFMGKNNLFVTEEYGCAFSMCTVLTDAPISVE
                     RYPLIDSKCMDCNVCVENCPAKAIHGNEWTLPGKRESIIDVSKCFCVLRCMMSCPWSL
                     RYANQK"
     gene            1913..3259
                     /locus_tag="PC512_003042"
     CDS             1913..3259
                     /locus_tag="PC512_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 55 protein"
                     /protein_id="HDF2442772.1"
                     /translation="MEIETKTPDWINVLELNSKIDITGKYDVSNMIQNIVSDKSLEGS
                     IIYFPKGNYLFEKGIKISQQITLQGDSYYGGGNQVSNLDKKQSIIGTTNFITRGVSNM
                     SIITLSGTSQCIKNINFYYDSHDIEKIPPKNVSAITEYGETQGLSHFEHLFISGFSGI
                     GIEIPYYSTGNDITVSSCGLGMRLGEKSMLSSSKIYECKNGMEITTGVSLNNVRIEEI
                     KEIGINNKGFGFNLIMNLMVDQCGYCGFMFEKMCYSQITARITRCGQYYKSVDYNAYE
                     NMEDRKEEAYSIFYGDILENCNIVLMNSNIDTLENDSLDEHKIYVIKANETNNVMLTC
                     YAEADNFIQCAKGNLLLENGENTYKFYNGEICSVGGVQISDIDEKDLIKIIENTLYID
                     DKGKYLMVPRLKKNTVIYSVLDSTEEINKLHGGIWEQIDVKVLAGESMYYYKKIKD"
     gene            3286..4686
                     /locus_tag="PC512_003043"
     CDS             3286..4686
                     /locus_tag="PC512_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442773.1"
                     /translation="MEESIIIKDISGWINVLDYGICNDETKDVSFKLQEIMDAVPEDS
                     IIYFPKGKYLFESGVKIKKRLTLCGDSYILANVPKNTAGVTQFTFKGKKNPKSENIAI
                     ITAKSVRHCIKSICFYSDSCDRDMTSNHEPPTDGKPRFHHNVIINYRNISAIVCEDKQ
                     GESGHYKNLSFSGFSGIALDMPNNSTANDITIFTSGLGISTGENSTIANSKVWGCVDG
                     MIISTGTFINGMRVEEIKKVGIKNIGRGLNFITNITIDQCGYCGVWFDSISNVQISGN
                     ITRCGQYYYDVSYDNYLMLDNRVKEAYSLFYGNLLESSNIVLSNTNKDNWEDFKEDKH
                     KVYLVEALETKNVLLTCNIDATDWIVKSEKGNLTYNNMRQTVIFYDGKLSSINGIGIS
                     DEDYGDKVKIKKGNIYINSKDKDIKMHKPEVGDIMSTIIKDKSILSAHYGGTWEKIGE
                     KIEFGITVHYYKLIEK"
     gene            4896..6332
                     /locus_tag="PC512_003044"
     CDS             4896..6332
                     /locus_tag="PC512_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 55 protein"
                     /protein_id="HDF2442774.1"
                     /translation="MEGRTGIKDGRWINVVERGIKNDGSYNVGPALQDIIDEIETDFC
                     VLYFPKGKYLFTSGVKINKEIVLQGDSNSSTGTTQFITRGVENMSIITLTGKKQCIKN
                     INFYSDSCEIQVNKEPPTKGNPKYHYEMIINKNEKNVEMNNVSAILYDNSKNMIKGLG
                     HYENIYISGFSGTGIRIPYYSIVNDITVSSCGLGIDTGIDTIISNSRISKCQNGMRIR
                     TGTSINNVRIEKIQKVGLISSQVKGYEGYGSYKINNITIDQCGYCGFSFDSMKDSYFS
                     GIIRRCGQYYYNTDYDTYLSIKDRVEEAYSLFYGNYFTECNIDLVSDNKDNWDDGLEY
                     KHKVYVFKTLQIPKLTLRCNIDAYDYIVKSVHGGGNLMLKNNFNNYIFIDSSNPEVIN
                     GINFNYQKNGNLLRLNNGKLSYKNGKEETAIFRPNYGLIVASTDSECEQIETSYGGKW
                     EKLGSEVIGEETVYYYKHHEPDKTNQIQ"
     gene            6676..7620
                     /locus_tag="PC512_003045"
     CDS             6676..7620
                     /locus_tag="PC512_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1848 domain-containing protein"
                     /protein_id="HDF2442775.1"
                     /translation="MIVSVSRRTDIPAFYSKWFFNRLKEGFVYVINPMNPKQVSKIEL
                     NPHTVDCFVFWTKDVTPMLYDLNKLKDYKYYFHYTITSYGKEVETCILDKRKVIDSFK
                     ELSRKIGKERVILRYDPIFLSEKYTVDYHIKAFASLCNQLDGFTEKCIISFIDLYKKT
                     KFNTKALHIKPIEITEIETLSKEISKIAHKHGITLEMCSEEYNLSKFGIGKSKCIDDR
                     LISKIIGCEVEVKKDSTQRDICGCVKSVDIGQYNTCRHYCLYCYANFNYAKVEENCRL
                     YKEDNKLLIDTLRDDAKISIRDMKTIKVDKNKQISIFD"
     gene            7789..8721
                     /locus_tag="PC512_003046"
     CDS             7789..8721
                     /locus_tag="PC512_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HDF2442776.1"
                     /translation="MNLLKKYPIPIASLILSIFTLGNLLQSYSESLRNVIGFIGFILY
                     AIYIVKIILLRKGVKEQLENTLISSTFPTITMATMIFATYIKPLSLELSIMIWSIGIV
                     GHLVLIVLFSKKFLVKFSIKTVFPSWYIVYVGIVAASVTAPAFNQLLIGKIAFWIGFV
                     SYIVLIPVILKRVWIIKEMPEPSLPSIAILAAPGSLLLSGYINSFSDKNNVVLYLLFI
                     LSIVFYIIVLGYLPKLLRLPFYPSFAAFTFPMAISAMGMKLMNGYLTKSGHFISWISY
                     ASKLEEIIATVIILYVLVLFIIYLSKSETTSKAK"
     gene            8826..9293
                     /locus_tag="PC512_003047"
     CDS             8826..9293
                     /locus_tag="PC512_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C_GCAxxG_C_C family protein"
                     /protein_id="HDF2442777.1"
                     /translation="MKTKEEYLKEVRNISEEYFRKGEFFCSEAVLQTINDALGQPLSP
                     EITKLASGFPIGLGKAQCLCGAISGGEMALGIVYGRVHGEAMNPKMFEHAKGLHDYIK
                     KEYGATCCRAITKKWDGDNFMSPERKEHCIKITGQVTEWVADKLIEDEKLNIK"
     gene            complement(9537..10391)
                     /locus_tag="PC512_003048"
     CDS             complement(9537..10391)
                     /locus_tag="PC512_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009912760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HDF2442778.1"
                     /translation="MLTIIIALLPVMGWGLMPIVANLKKSSPHEQLLGTSISAFIFST
                     IITLVIHPEITFFSFCISMISGIFWSLGQLMQFKAIQIASVSKVMPISNGSQLTFTTL
                     LAVILFNEWTSSKMLLIGSLSILCIILGILLTNYQTKKSTDKNMLKCVGVVLLSSLFL
                     SLYVVTNQIFLIEGYRIILPQSVGMLITSSIIVKYFSKEIVYRENVLFNLITGILWSI
                     ANLGMFITTNTLGVTISFSISQSCVIVATLGGIIFFKEKKNKKEWLAIFIGIILIMSG
                     VFMLSIIK"
     gene            10557..12521
                     /locus_tag="PC512_003049"
     CDS             10557..12521
                     /locus_tag="PC512_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF2442779.1"
                     /translation="MLTDMIQNREIKIIKFLLKEGHTTVKAIADDLDVSEKTVSKSLK
                     EVEAVLKKIGLSLIRKPKIGVYIDGDLKKILPYLDNKGSQIPTTREERVIYIYSVLLK
                     SNDYITIQQLSDELYISRGTIERDLAEVEKLLKNEGISIYKKPSKGIKLNISERDKRQ
                     LTAKFIHKFWSRNWYIKQEQESFYQAFEKIQADVNGIFSEDDLSIIIDILRNFSRERK
                     FEFSDYEFQSLVIHLAIAVERIRKGEYIEESLYTGNIENNQMSNTNYLAKQLEEKFSI
                     LLPKSEIGYINLHLVASDQHRDTNELKNTSTNPCETSTNNISNLREIIKNTLYETAYD
                     KDLIDGLTSHVHSSINRLKYGLSIKNPYVNTIKQNFSLSFEQALDLKKVIEFIYDIRI
                     NDDECAYIALHFEAFRERMKELPQNIRVILVCSTGLGSSRLLSARIKKYFPMIKIEKV
                     LSVQELVSSKIDADLVISTIYLELETIPTIVVSPILNESDIRTLERNIQNVSSCTSKK
                     YKSFRNLIFEENILLNIEASNYEDAIKYITDNLIKKGFAKEGIAKSAIERENLSYTSF
                     QSIATPHANPSYIKKSNISVATLKNPITWGNEKVEVIFFISLENDKNLELDEIYEVFY
                     DFIDNKKNINDILSATSTKEVYDLLVEESI"
     gene            12521..12982
                     /locus_tag="PC512_003050"
     CDS             12521..12982
                     /locus_tag="PC512_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2442780.1"
                     /translation="MKISDVLKKEQIVFNLDTNTKEETIKKLSSIFVENGIVDNEEEY
                     VKSVLEREEHSTTGIGNGIAIPHGKSNAVKKSSIIFAKTKHKIEWDALDEKPVDSIFL
                     LAISNIDKDSNHLVLLSKLATKLMDDDNVDALKLANSEQEIINIFSEEGEM"
     gene            12985..13305
                     /locus_tag="PC512_003051"
     CDS             12985..13305
                     /locus_tag="PC512_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HDF2442781.1"
                     /translation="MKRKIIAVTACATGVAHTYMAAQALKKASKKMGHLIKVETQGAT
                     GIDNELTTKDAQIAEVVIFAVDTKVRNAERFEGKEILEVPVNAPIKDAEKVINDALKL
                     IDTK"
     gene            13321..14421
                     /locus_tag="PC512_003052"
     CDS             13321..14421
                     /locus_tag="PC512_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HDF2442782.1"
                     /translation="MLKKIVSELKKHVLTGISYMIPLVIAGAMIMAISRVGGSFYNIP
                     DIWDAKYAESASSIVRLLHDLDGFGGTALGLMFPVIAAFIGFSIADKLAIVPGLVGGM
                     IAKDIGAGFLGALAVGLIAGYTCLFIKNHVKLPKSAASIVPIFIVPVFGTLITVVLIN
                     YVIGIPFATLNTGLENWLNGLSGTNQILMAAIIGAMMAVDLGGPVNKAALTTSLALLT
                     SGIYAPNTAAMVGIVIPPLGLGLATILAKQKYNKQLREAGKSSLIMGLIGVSEGAIPF
                     AVESPLKVIPSCVIGTAIASAMAVGLGSVNATPISGFYGWFTVENWPMYVLSIAVGTV
                     IVAGLVIVLRGNPVIEDDEFEDDDFDEAEWES"
     gene            14541..17141
                     /locus_tag="PC512_003053"
     CDS             14541..17141
                     /locus_tag="PC512_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HDF2442783.1"
                     /translation="MIKAHIVNHTHWDREWYFTSGDALVLSEQLFTDVIDELERNPDV
                     SFVLDGQLSILDDYVQLHKEKIEIIKKLIKEDRLHIGPWFTQTDAFFARGESILRNLM
                     IGIFESKKYGKYMKIGYLPDTFGFNAQMPILLKHVGLDNIFFWRGIHLGKQVQSPYFK
                     WKSLNGESYIYAVNMPHGYGTGMLLEPSLKYVNGRLDPAIDFIKSYTDVDEVLIPSGN
                     DQLNIIGDFKNKIKAINDIGKYSYITSSYQEFLKYIKSIESLESYRGEFREPVLARIH
                     KSIGSSRMDIKLACDKLENKLIKRIEPLLVIAKKSKIEISNQLLINTWKKLLEGQAHD
                     SLAGCVTDTVTDDILHRIREANEICDSIENTIVKKISEGLKLSKNDILVFNTEAKRFN
                     GYKEIQVVSDSKNIYFKDNLDATIIEETYVKPRENVLEETPAGNIFIEEPGYYILKVR
                     INVQLPALGYKVVSFELSDKEMVSLDKSNDTFISNDNYKIIYEDGSLNLQLKDGTYIS
                     NFLTLKDSGNAGDTYDFSPLKNDENIKLSFDKVYTEKALGYEKMVVKGTTLLPLTLED
                     RKNKYLNGKLNVKVSIVLSKENPLMDVKLCVDNTIYNHRLRVHIKTDIKDNKNIASLP
                     FGYITRKNGVLDNWEDIYSEMPIDLEPLESNITLTNQNRSCTVFTRGIKEYQHIEDEI
                     ALTLLATTDELGKPDLLYRPGRASGDTTKKGHIRIKTDKAQMLKELEFSFAIYMDSKS
                     FDELEIANLTHNYLRECVNYQLQDYNFFLYHIDNKIQKSIVNKTVSRELEIISLPENY
                     LISACYPSYYSKDKFIIRVENPSSNRMILDEQIFKNRNGKIVNAIEDVEEEQVYEIAP
                     FDVISILLDL"
BASE COUNT         6890 a         1780 c         2997 g         5663 t
ORIGIN      
        1 attaataaac tttaatataa tatatttatg aaaaatgtaa actgtgaaat ggaggtagta
       61 acatgaaaat tgaaaatctt tctattgatg atattaaacg aggctatata tttaatgatg
      121 atttaaattg ttatagttgc attaaatgta caaaaacata tgaggtagga gaaatatata
      181 aaataggtaa tagattcttt gaagcttcaa aagctattga acttcatatg gaattagaac
      241 atagtgatta tttagagcaa ttgcttaata gtgattcaaa atacaacaca ttgactgaaa
      301 atcaaaaaca attatttcaa ttatttatta gtgatttacc agataaggag atagcaaaac
      361 aggttggagt atccacatct actatacgcc atcaaaaatt tattttcaga gaaaaagcaa
      421 aacaggctaa gctctattta gcactatatg aatctgtatt tgaagataaa tctaataaaa
      481 gtagtactat aataccaatc catgaacatg ctcgaatggt agatgaaaga tatgtagtaa
      541 ctgaagaaga gagaaaacac attttggata catcatttga aagtatgaat cctttaaaat
      601 taaaagtatt ttcttcaaaa gaaaagaaaa aggtcgtaat tttatctaag attttggaac
      661 aatttgaacg tgggaagaaa tattcagaaa aggaagttaa tcagatttta gaatctatat
      721 atgatgattt tgcaacaatt agaagatatc taattgagta tggttttatg agtagaaata
      781 aagaatgtac aaaatattgg ttaacataat taaaataata aattttacta atgtgtaatg
      841 ttatttttat ctagggggag gagtcaaata tgaatgatga attaaaatct attttataca
      901 ataaaggtgt agacattgtt cgctttgttg atatatctga atttccaata aatcaaacac
      961 aaggtttttc taaagcaatt ttattttgta tagggttatc aaaaaaattt attacagata
     1021 tatacaataa cttacctaca gatagtgatg agtttttgga aaaagaggag aaagtagaag
     1081 aattagctga ctggatttca aaatatattc aaaataaagg atatagagca tattctcaat
     1141 cggagaaaaa caatctagaa catggatatt ttgaaaaagc ctatattaat ccagaaatgc
     1201 aatcagggat tagtccttta ccacataaga caatagcaaa tattagtggc attggattta
     1261 tgggaaaaaa taatttgttt gtaacagagg aatatggatg tgcttttagc atgtgtacag
     1321 tacttacaga tgctccaatt tctgttgaaa gatatccttt gattgattca aaatgtatgg
     1381 attgcaatgt ttgtgtagag aactgtcctg caaaagctat acatggaaat gaatggactt
     1441 tacctggaaa aagagaatct attattgatg tttcaaagtg tttttgtgta ttgaggtgta
     1501 tgatgagttg cccatggtca ttaagatatg caaatcaaaa ataactttac tagagaaggt
     1561 attaaattga atattataaa atttttaaaa tgtaagatta tataagattt ctcaaaataa
     1621 aaatttgtat agaacactca gaaatgagtg tttttttatt gggattaaat tatattgata
     1681 caaagcttaa ctattttaat cattatataa aatttgtatt aaaaaattaa gaataacttg
     1741 gtaatagtga aaatataatg agattataat tgatttataa tataactata atgatattgt
     1801 aaaaatgaaa attgtcctct caaaattccc aaagagagta aaagtcactt cagttatagt
     1861 caaaaaaatt tttctgtgaa aagaatttag atttgaaaag gaggaattaa tcatggaaat
     1921 tgaaactaaa actccagatt ggattaatgt actagaatta aacagtaaaa tagatattac
     1981 tgggaaatat gatgtaagta atatgataca aaatattgtc tctgataagt cactagaagg
     2041 ttccattata tattttccaa aaggtaatta cttatttgag aaaggtatta aaattagtca
     2101 acaaataaca cttcaaggag attcttatta tggaggaggt aatcaagtat caaatttaga
     2161 taaaaaacaa tcaatcatag gaacaaccaa ttttataacc cgaggagttt ctaatatgag
     2221 tattattaca ttgtcaggaa caagtcaatg tatcaaaaat attaattttt attatgatag
     2281 tcatgatata gagaaaatac cgcctaaaaa tgtatctgct attacagaat atggagaaac
     2341 acaaggacta tctcattttg aacatctgtt tatttctgga ttttcaggga taggaattga
     2401 aattccatac tattcaactg gtaatgatat tactgttagt tcatgtggtc ttggtatgag
     2461 gcttggagag aagtcaatgc tttctagtag caagatttac gaatgtaaaa atggaatgga
     2521 gattactact ggtgttagct taaataatgt gagaatagaa gaaataaaag aaataggtat
     2581 taataataaa ggatttggtt ttaacctgat tatgaatctt atggtcgacc aatgtggata
     2641 ttgtggattt atgtttgaaa aaatgtgcta tagccagata actgccagaa ttactagatg
     2701 cggtcagtat tataaaagtg ttgattataa tgcttatgag aatatggaag ataggaaaga
     2761 agaagcttat tccatttttt atggagatat tttagaaaat tgcaatattg tattgatgaa
     2821 tagtaatatt gataccttgg aaaatgattc acttgatgaa cataagatat atgtaatcaa
     2881 ggcaaatgaa acaaacaatg taatgctaac atgttatgct gaagcagata actttataca
     2941 atgtgcaaag ggcaacttgc tgttagaaaa tggtgaaaat acttataaat tttataatgg
     3001 tgagatttgt tctgtaggag gtgttcaaat ttctgatata gatgaaaaag atttaatcaa
     3061 aataatagag aacactttgt atatagatga taaaggtaag tatttaatgg ttcctagatt
     3121 aaaaaagaat actgtaatat attcagtact agattctaca gaagaaataa ataaattaca
     3181 tggtggaata tgggaacaga ttgatgtaaa agtattagct ggggaatcca tgtactatta
     3241 taaaaagata aaagattaaa ttatcaaact aggaggtagt gattaatgga agagtctata
     3301 ataattaaag atataagtgg ctggattaat gtccttgatt atggaatttg taatgatgaa
     3361 acaaaagatg taagttttaa gttgcaagag attatggatg ctgtaccaga agattctatt
     3421 atatattttc caaaaggaaa atacttattt gaaagtggtg ttaagattaa gaaacgatta
     3481 actttatgtg gagattctta tattttggcg aatgttccta aaaatactgc tggagtaaca
     3541 caatttactt ttaaaggaaa gaaaaatcct aaaagtgaaa atatagcaat tataacagca
     3601 aaaagtgtaa gacactgtat taagagcatt tgcttttatt cagatagttg tgatagagat
     3661 atgacatcta atcatgaacc tccaacagat ggaaaaccta gatttcatca taatgtaatt
     3721 ataaattata gaaatatatc ggctattgta tgtgaagata aacagggaga atcaggtcat
     3781 tataaaaatc tatcttttag tggtttttct ggaattgcac ttgatatgcc taataattct
     3841 acagcaaatg atattacaat ttttacatcc ggacttggaa ttagtacagg agaaaattca
     3901 actattgcta acagtaaggt ttggggctgt gttgatggaa tgataatttc tactggaact
     3961 tttataaatg gtatgagggt agaagaaata aaaaaagttg gaattaaaaa tattggtaga
     4021 ggtttaaatt ttattacaaa tatcacaatt gaccaatgtg gatattgtgg agtttggttt
     4081 gattctatat ccaatgttca gatatcagga aatatcacaa ggtgtgggca gtactattat
     4141 gatgtaagct atgataatta tttaatgttg gataatagag ttaaagaagc atattcttta
     4201 ttctatggta atttattgga atcaagtaat atagttttat caaataccaa taaagataat
     4261 tgggaagatt tcaaagaaga taagcataag gtgtatcttg tagaagcact tgaaaccaag
     4321 aatgtactat taacatgcaa tatagatgct actgactgga ttgttaagtc agaaaaagga
     4381 aatttaacgt acaataatat gcgacaaact gttatatttt acgatggaaa actaagtagt
     4441 atcaatggaa ttggtatatc tgatgaagat tatggggata aagtcaagat aaaaaaagga
     4501 aatatatata taaatagtaa ggataaggat attaagatgc ataaaccaga ggtaggtgac
     4561 attatgtcaa caattattaa agataaaagt attctttctg ctcattatgg gggaacatgg
     4621 gagaaaattg gtgaaaaaat agagtttgga ataactgtac actattataa attgatagag
     4681 aaataagtaa atacgtagta tttgaataga tgtattttat tggagagcta ggactatagt
     4741 tttaatgtaa atggtttggt aatagcatgg attgaataat ataaaaataa tataaaaaat
     4801 taatttgatt atgtaaaatt ctatgaagta gtaaaactgt gactttagtc ataggaggtt
     4861 caaactaagt aaaagggaaa ggaatatata atattatgga aggaagaact gggattaaag
     4921 atggaagatg gattaatgta gtagaaagag gtattaaaaa tgatggttcg tacaacgtag
     4981 gtcctgcttt gcaggatatt attgatgaaa tagaaacaga tttttgtgtc ttatattttc
     5041 caaaaggtaa atacctattt acaagtggtg ttaaaattaa taaagaaatt gtattgcaag
     5101 gtgattctaa ttcatctaca ggcactacac aatttataac tcgtggagta gaaaatatga
     5161 gtattattac attgacaggg aaaaaacaat gtattaaaaa tataaatttt tattctgata
     5221 gttgtgagat acaggtaaat aaagaaccac cgacaaaagg taatcctaaa tatcattatg
     5281 agatgattat taataagaat gaaaagaatg ttgagatgaa taatgtatca gcaatcctgt
     5341 atgataacag taagaatatg attaaaggtc taggtcatta tgaaaatatt tatataagtg
     5401 gtttttcggg tacaggaatt aggataccat attactcaat tgtaaatgat attacagttt
     5461 catcttgtgg gctgggtatt gatacaggaa tagacacaat tatttctaat agtagaatat
     5521 ctaagtgtca aaatggaatg aggattagaa ctggaactag tataaataat gtaaggattg
     5581 aaaaaataca gaaagttggt cttataagta gtcaagttaa ggggtatgag gggtatggaa
     5641 gttataaaat taataatatt acgattgacc aatgtgggta ttgtggcttt tcatttgatt
     5701 caatgaaaga tagttatttt tctggtatta taagaaggtg tggtcagtat tattataata
     5761 cagattatga cacatattta agtattaaag atagagtaga agaagcatat tctttatttt
     5821 atggaaatta ttttacagaa tgtaatattg atttagttag tgataataag gataactggg
     5881 atgatggctt agaatataaa cataaagttt atgtatttaa aacccttcaa ataccaaaat
     5941 taacattgag atgcaatata gatgcctatg attatatcgt taaatcggta catggaggag
     6001 gtaatttaat gttaaaaaat aattttaaca attatatatt tattgattca tctaatccag
     6061 aagttattaa tggaattaat tttaattatc aaaagaatgg aaacttgtta aggttaaata
     6121 atggtaaatt aagttataaa aatggaaagg aagaaacagc tatattcaga cctaattatg
     6181 gtcttattgt agcatcaaca gattcagaat gtgaacaaat agagactagc tatggaggaa
     6241 aatgggagaa gcttggttct gaagtaattg gagaagaaac ggtatattat tataaacatc
     6301 atgaaccaga taaaacaaac caaatacaat aaaatttgta ttatataatg atataaagtt
     6361 ttaatatata gtgtttacct ttaatgtaat attggtatat ttgtatagta ttaaatttgt
     6421 taaaaagtaa aattgtaggg tgcttgaaaa tagcaccttt tttagtttca ttataaaatt
     6481 agttttgaaa gtttaggaat aatgtatatt tatttttaaa gaattataac cttattaagg
     6541 atattttaaa tgctagaaat gaatcagtaa atcatactgg aattatctta aatgttttga
     6601 ttaaattaag tatttagagc tataattata ttaaaaatat attagaacat aattatatta
     6661 ctatggaggt taaatatgat agtaagtgtg agtagaagaa ctgatatacc tgctttctat
     6721 agtaagtggt tttttaacag acttaaagaa ggttttgttt atgtaattaa tccaatgaat
     6781 ccaaaacagg ttagtaagat agagttaaat ccacatactg ttgattgttt tgtattttgg
     6841 acaaaggatg taactccaat gttatatgat ttaaataaat taaaagacta taaatattat
     6901 tttcactata ctataacatc atatggaaaa gaagtagaga catgtatttt agataaaaga
     6961 aaggtaatag attcatttaa ggaattgtct agaaaaatag gcaaagaaag agtaatttta
     7021 agatacgacc cgattttctt aagtgaaaag tacacagtag attatcatat caaagcattt
     7081 gcgagtttat gtaatcagct tgatggattt acagaaaaat gtataataag ttttatcgat
     7141 ttatataaga aaacaaaatt taatactaaa gcattacata taaagccaat agaaattaca
     7201 gaaatagaaa cattatcaaa agagatttct aagattgctc ataagcatgg gataacactt
     7261 gaaatgtgtt ctgaagaata taatttaagt aaatttggga ttggaaaaag taagtgtatt
     7321 gatgatagat taatatcaaa aattatagga tgtgaagtag aggtaaaaaa agatagtaca
     7381 caaagagata tttgtggatg tgttaaaagt gtcgatatag gacaatacaa tacttgcaga
     7441 cattattgtc tgtattgtta tgctaacttt aattatgcaa aagtagaaga aaactgtagg
     7501 ctttataaag aagataataa attactcata gatactttaa gagatgatgc aaaaataagc
     7561 attagagata tgaagactat taaagtagat aagaataaac aaattagtat atttgattaa
     7621 aataaatata ctaattacct taatatatta agaatataga tacttttgat aacaaaatta
     7681 aacttaatag atattttcta tataagaaag atggtcataa tatgtcaatt tgaccatctt
     7741 tttgatataa ttaaaacaca aataatttag taacaaagga ggcagaactt gaatttatta
     7801 aaaaaatatc ctatacctat tgcaagtttg attttgtcaa tctttacttt aggtaactta
     7861 ttacaatctt atagtgaatc attacgtaat gtaattggat ttataggatt tattttgtat
     7921 gcaatttata tagtcaaaat aatattactt agaaagggtg ttaaagagca attagagaac
     7981 actttaatat caagtacatt tccaactata acaatggcaa caatgatatt tgctacatat
     8041 ataaaaccat tatctttaga attaagtatt atgatttgga gcataggaat tgtgggtcat
     8101 cttgtgttaa tagtcttatt tagtaagaag ttcttagtta aattctcaat aaaaacggta
     8161 tttccatctt ggtatatagt atatgttggg atagttgcag ctagtgttac ggcaccagca
     8221 tttaatcaac ttttgattgg caaaattgct ttttggatag gatttgtatc ttatatagtt
     8281 cttataccag taattttaaa gagagtatgg ataatcaagg aaatgcctga accatcttta
     8341 ccaagtatag ctatattagc tgcaccaggg tcactattat tgtctggata tattaattct
     8401 ttttcagata aaaataatgt agtattatac ttgttattca tattatcaat tgtattttat
     8461 attatagttt tgggatattt accgaaatta ttaagattgc ctttttatcc gagttttgct
     8521 gcatttacat ttcctatggc aataagtgca atgggtatga aactaatgaa tggttattta
     8581 actaaatcag gtcattttat aagttggatt tcatatgctt ctaagttaga agagataatt
     8641 gctacagtga ttattttata tgttttagtt ttgtttatta tatatcttag taaatctgaa
     8701 actacatcta aagctaaata agaattatta aatatgtgta tttaatagga atattgatat
     8761 aaatatatga agataagata aaccatagaa acttaattta gcttaatttt attggaggaa
     8821 aacaaatgaa aacaaaagaa gaatatttaa aagaagttag aaacatatca gaagaatact
     8881 ttagaaaagg agagtttttt tgctctgaag cagttctcca gacaataaat gatgctttag
     8941 gccaaccttt aagtccagag ataactaagt tagcatcagg atttccgata ggacttggaa
     9001 aggcacaatg tctttgtgga gcaatatctg ggggagagat ggctttaggt atagtatatg
     9061 gaagagttca tggtgaagct atgaatccaa agatgtttga gcatgctaaa ggtttgcatg
     9121 attatattaa aaaagagtat ggtgcaacat gttgtagagc tattacaaag aaatgggatg
     9181 gtgataactt tatgtctccc gaaagaaaag agcactgtat taaaataaca ggtcaagtta
     9241 cagagtgggt tgcagataag cttatagaag atgaaaaact taatatcaaa tagtgtaata
     9301 ttagttggtg aatttataaa gttaaattta cttatagtat aagatacttg atattctcgt
     9361 attgatagaa aaatttatag catatgtatt taatgaaata tacttatatt tagagtgtgg
     9421 tttaatttca taaatacata tgctattatt ttaagtatat aagcaaattt atttaaataa
     9481 atagaaacag ttaatttata tgtacaaaac tatatatgat tagtgtaaat aaatacctat
     9541 tttataatac tcaacataaa gacaccagac atgattagta ttataccaat aaaaatagca
     9601 agccattctt ttttgttctt cttttcttta aaaaatataa tccctcctaa agtggctact
     9661 atcacacaac tctgagagat agaaaaactt attgtaactc ccaatgtatt agtcgttatg
     9721 aacataccta aatttgctat tgaccacaat ataccagtaa ttaaattgaa taaaacattt
     9781 tccctatata caatctcttt agaaaaatac ttgacaataa tagatgaagt tatcaacata
     9841 ccaacagatt gaggtaatat aattctatat ccttcaatta aaaatatttg attagttaca
     9901 acatataatg ataaaaatag agatgataat aatacaactc caacacattt taacatattt
     9961 ttatctgtag attttttagt ttgataattt gtgagaagta taccaagtat tatacataat
    10021 attgataaag aaccaatcag taacatttta gaactggtcc attcattaaa caagattaca
    10081 gctaataatg tcgtaaaagt taattgtgaa ccatttgaaa ttggcattac tttagataca
    10141 ctagcaattt gaattgcttt aaactgcatt aattgtccca aactccagaa tatgccagaa
    10201 atcatactta tacaaaatga aaaaaatgta atttcaggat gtataaccag agttattata
    10261 gtggaaaata taaacgcact tatggatgta cctaaaagct gttcatgagg agaacttttc
    10321 tttagatttg caactatggg catcaatccc catcccatta caggaagtaa agcaataatt
    10381 attgtcagca ttaaactatt tcctttcata ttaaatttag acagctttta atttatcatc
    10441 taaaattaaa gtgttcaata cataaaaatt accgtattta atcaggaaat attagtagtt
    10501 ttttagaaaa acattttcca ttaaaataaa gacaaaggga aggagtaaaa ttgaaaatgt
    10561 taactgatat gattcaaaat cgtgaaatta aaataataaa gtttttatta aaagaaggtc
    10621 atacaactgt aaaagcaata gcagatgatt tagatgtttc agaaaaaaca gtttcaaaat
    10681 ctcttaaaga agtagaagca gtgcttaaaa agataggtct ttctttaata agaaaaccta
    10741 agataggtgt ttatattgat ggagatttaa aaaaaatact tccttaccta gataataaag
    10801 gaagtcaaat tcctacaacc agagaggaga gagttatcta tatatattca gtacttttaa
    10861 agagtaatga ttatattact atacaacaac tttctgatga actatatata agtcgtggaa
    10921 ctattgaaag ggatttagca gaagttgaaa aactgctaaa aaacgaaggg atttccatat
    10981 ataagaaacc tagtaaggga ataaagttaa atataagtga aagagataaa agacaactta
    11041 ctgctaagtt tatacataaa ttttggagta gaaactggta tattaagcaa gagcaagaaa
    11101 gcttttatca agcatttgaa aagatacaag cagatgtaaa tggtattttt tcggaagatg
    11161 atttatcaat aattattgat attcttagga atttcagcag agaaagaaaa tttgagttct
    11221 ctgattatga atttcagtca ttagttattc atttggcaat agctgtagag agaattagaa
    11281 aaggcgaata tatagaagaa agtttgtata ctggtaatat agaaaataat caaatgtcaa
    11341 ataccaatta tttagcaaaa caattagaag aaaaattttc aatattatta ccaaaatctg
    11401 aaattggata tataaattta catttagtag cgtctgacca acatagagat actaatgaac
    11461 taaaaaatac ttcaactaat ccttgtgaga caagtacaaa taatatatca aatcttcggg
    11521 aaattataaa aaatacattg tatgagacag cttatgacaa ggatttaatt gatggattga
    11581 cttcacatgt acattcatca ataaatagac tgaaatatgg acttagtatt aaaaatccat
    11641 atgtaaatac aatcaaacaa aacttttctt tatcatttga gcaagcttta gatttaaaga
    11701 aagtaattga atttatatat gatattagga taaatgatga tgaatgtgct tatatagcat
    11761 tacattttga agcttttaga gaaagaatga aagaacttcc acaaaatatt agagtaattc
    11821 tagtatgcag tacaggatta ggttcatcta ggttattgtc tgcaagaata aaaaaatact
    11881 ttccaatgat aaagattgaa aaagtacttt ccgtacaaga attagtatcc agtaaaattg
    11941 atgcagattt agtaataagt actatttatt tagagttaga aacaattcca accatagtag
    12001 ttagtcctat tttaaatgaa agtgatataa gaaccttgga aagaaatata caaaatgttt
    12061 caagttgtac ttctaagaag tataaatctt tcagaaactt aatctttgaa gaaaatatat
    12121 tgttgaatat tgaagcttca aactatgaag atgcaattaa gtatataaca gataacctaa
    12181 taaaaaaagg ttttgcaaaa gaaggtatag ctaaaagtgc aattgagaga gaaaatttat
    12241 cttacacttc tttccaatca atagctacac ctcatgctaa tcctagttat attaaaaaat
    12301 ctaatatatc tgttgcaacg ttaaaaaatc ctattacatg gggaaatgaa aaggtggaag
    12361 ttattttctt tatttcatta gaaaatgaca aaaacctaga gcttgatgaa atatatgaag
    12421 ttttttatga ctttattgac aataaaaaaa atataaatga catattaagt gcaacttcca
    12481 caaaggaagt gtacgatttg ctagtggagg agagtatata gtgaaaatat cagatgtatt
    12541 gaaaaaagag caaattgttt ttaatcttga tacaaataca aaggaagaaa caataaaaaa
    12601 attaagtagt atatttgttg aaaatgggat tgtggacaat gaagaagaat atgttaagtc
    12661 tgttttggaa agagaagaac attcaactac aggtattggt aatggtattg ctattcctca
    12721 tgggaaaagt aatgctgtca aaaaatcttc tataatattt gcaaagacta agcataagat
    12781 tgaatgggat gctttagatg aaaaaccagt agatagtatt ttcttattgg ctataagcaa
    12841 tattgataag gatagcaatc atcttgtact attatctaaa ttagcaacta aacttatgga
    12901 tgatgacaat gtagatgcac taaaattagc caattcagaa caagaaataa tcaatatatt
    12961 tagtgaagaa ggagagatgt agaaatgaaa agaaaaatta tagcagttac agcatgtgca
    13021 acaggagttg cacatacata tatggcagct caagcattaa agaaagcttc aaaaaagatg
    13081 ggtcacctta taaaagttga aacacaagga gctacaggaa tcgataatga gttaactaca
    13141 aaggatgcac aaattgcaga agtagtaata tttgcagtag atactaaagt cagaaatgct
    13201 gaacgttttg agggaaaaga aatactagaa gtaccagtta atgcacctat aaaggatgca
    13261 gagaaagtaa taaatgatgc attaaagtta attgacacta aataaatgga gggaaatgta
    13321 atgttgaaaa agatagtctc tgagttaaaa aagcatgtct taactggaat ctcatatatg
    13381 attccattag taattgcagg tgctatgata atggcgatat ctcgtgtagg tggttctttc
    13441 tataatatac cagatatatg ggatgctaaa tatgcagaaa gtgctagtag tattgttaga
    13501 ttattacatg atttagatgg gtttggaggt actgcattag gattaatgtt tcctgtaatt
    13561 gctgcattta taggattttc tatagctgat aaattagcta ttgtaccagg tcttgttgga
    13621 ggtatgattg ctaaagatat aggtgcagga tttttaggag ctttggcagt tggtcttata
    13681 gcaggatata catgtttgtt tattaaaaat catgttaaat taccaaaatc agcagcttca
    13741 atagtaccaa tatttatagt accagtattt gggacattaa tcactgttgt attaatcaat
    13801 tatgtgatag gtataccttt tgccacatta aatactggat tagaaaattg gttaaatgga
    13861 ttatctggta caaatcagat actaatggca gctattatag gggctatgat ggcagttgac
    13921 ttaggtggac cagttaataa agcagcttta acaacatcac ttgcattatt aacaagtgga
    13981 atttatgcgc ctaacactgc tgcaatggta ggaatagtta taccaccact aggattggga
    14041 cttgctacta tactagcaaa acaaaaatat aataaacagt tacgtgaagc tggaaaatca
    14101 tctcttataa tgggtttaat tggagtaagt gaaggagcaa ttccttttgc ggtagaatct
    14161 ccattaaaag taataccttc atgtgtaatt ggaacagcaa ttgcttcagc tatggcagtt
    14221 ggtttaggtt cagtaaatgc aactccaatt agtggatttt atggatggtt tacagtagag
    14281 aattggccaa tgtatgtgtt atcaatagca gttggaacag taattgtagc tggattagtt
    14341 atagtattgc gtggaaatcc agtgattgag gatgatgaat ttgaagatga tgattttgat
    14401 gaagcagagt gggaatctta aaatttaata actatttaag acgtgttata agctatattc
    14461 aatatgaatc ttatactaaa taaagtgtta aatattcagt ttagacttaa atataaaaga
    14521 taaagaacag aggagaataa atgataaaag cacatattgt taatcataca cactgggata
    14581 gagaatggta ttttacttct ggagatgcat tagtacttag tgaacaacta tttacagatg
    14641 taattgatga attagaacgt aatccagatg taagttttgt acttgatgga caactttcta
    14701 ttttggatga ttatgtacaa ttacacaaag aaaaaataga aatcattaaa aagttaataa
    14761 aagaagatag actacatatt ggaccatggt ttactcaaac tgatgcattc tttgctagag
    14821 gagagtctat tttaagaaac ttaatgattg gaatttttga aagtaaaaag tatggtaagt
    14881 atatgaaaat tgggtatttg ccagatacat ttggatttaa tgcacagatg cctatactat
    14941 taaagcatgt aggtcttgat aatatattct tttggagagg tatacatctt ggtaaacagg
    15001 ttcaatcacc atattttaag tggaaaagct taaatggaga aagttatata tatgcagtaa
    15061 atatgccaca tggatatgga actggtatgc ttttagagcc ttcattaaag tatgttaatg
    15121 gacgcttaga cccagctatt gattttatta aatcatatac tgatgtagat gaggtgttaa
    15181 taccttctgg gaatgaccag ttaaatataa taggtgattt caaaaataaa attaaagcga
    15241 ttaatgatat cggaaagtat tcatatataa cgagttcata tcaagagttt ttaaaatata
    15301 taaagtccat agaatcacta gaaagctata gaggtgaatt tagagaacct gtattagcaa
    15361 gaatacataa atcaattggt tctagtagaa tggatataaa attagcatgt gataaactag
    15421 aaaacaagct gattaaaaga atagagccat tattagtaat tgctaaaaag agcaaaattg
    15481 aaataagcaa tcagttactt ataaatacat ggaaaaaact tttggaagga caagcacacg
    15541 atagtttagc tggatgtgta actgatactg taacagatga tattcttcac cgtataagag
    15601 aagcaaatga aatatgtgac agtattgaaa atactattgt aaaaaagatt tcagaagggc
    15661 ttaaattatc taaaaatgat attttagtat ttaatacaga agctaagcgt tttaatggat
    15721 ataaagagat acaagttgta agtgatagta aaaatattta ttttaaagat aatttagatg
    15781 ctactataat tgaagaaact tatgtaaaac cgagagaaaa tgtattagaa gaaacacctg
    15841 ctggtaatat atttattgaa gaaccaggat attatatatt aaaagtaaga ataaatgtac
    15901 agcttcctgc acttggttat aaagttgtta gttttgaatt aagtgataaa gaaatggtgt
    15961 cacttgataa atctaatgac acttttatat ctaatgataa ttataagata atatatgaag
    16021 atggaagctt aaatttacaa cttaaagatg gaacttacat atcaaacttt ttaacattaa
    16081 aagatagtgg taatgcaggt gatacctatg acttttctcc actaaaaaat gatgagaata
    16141 taaaactttc gtttgataaa gtgtatacag aaaaagcttt aggatatgaa aaaatggtgg
    16201 ttaaaggtac tactttacta ccacttacat tagaagatag aaaaaacaaa tatcttaatg
    16261 gtaaattaaa tgtaaaagta agtattgtct tatctaaaga aaacccattg atggatgtaa
    16321 aactttgtgt tgataacacg atatataatc atagactacg tgttcatata aaaactgata
    16381 taaaagataa taaaaacata gcatcattgc catttggata tataacaaga aaaaatggag
    16441 ttttagacaa ctgggaagat atttacagtg aaatgcctat agatttagaa cctttggaaa
    16501 gtaatattac gcttacaaac caaaatagaa gttgtactgt atttactaga ggaataaaag
    16561 agtatcaaca tattgaagat gaaattgcat tgaccttact tgctactaca gatgaactag
    16621 gaaagcctga tttattatat agaccaggac gtgcttctgg tgatacaact aaaaaaggtc
    16681 atataagaat taaaacagat aaagctcaaa tgcttaagga attagaattt tcatttgcaa
    16741 tatatatgga ttctaaatca tttgatgaat tggaaattgc gaatttaacc cacaattatc
    16801 taagggaatg tgtaaattat caattacagg attacaattt ctttttatat catatagata
    16861 ataagattca aaaatcaatt gtcaataaaa ctgtaagtag agaattagaa ataatatctt
    16921 taccagaaaa ctatcttata tcagcatgtt atccttctta ttacagtaaa gataaattta
    16981 taataagagt ggaaaatcca agtagtaata gaatgatatt ggatgagcaa atatttaaaa
    17041 atagaaatgg gaaaattgta aatgcaatag aagatgtaga agaggaacag gtatatgaaa
    17101 tagcaccttt tgacgttatt tcaatattat tggatttata agtgtaaaag taagtttatt
    17161 gtttaaagtc tgacagatat taatctgcca gactttttaa tttgtataaa tttgggtaaa
    17221 tattaatgaa tggttttagt atttaagtat gaatttagta tttaatatag aatttattga
    17281 agtagaataa ttagtttaac aggataagca gtttaaataa agaattatta
//
LOCUS       DAMJVG010000085        16505 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.086, whole genome shotgun sequence.
ACCESSION   DAMJVG010000085 DAMJVG010000000
VERSION     DAMJVG010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16505)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16505)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16505
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.086"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            107..988
                     /locus_tag="PC512_003054"
     CDS             107..988
                     /locus_tag="PC512_003054"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HDF2442784.1"
                     /translation="MLFKGSAVALVTPFTEDNNVNFEKLGELIEYHIENGTDALVVCG
                     TTGEATTMSESEIFAVIKYTVEKVNKRIPVIAGTGSNNTMLSVHMSQEAEKLGVDGLL
                     IITPYYNKTNEKGLKLHFETIANSVKLPIILYNVPGRTKVNIKPSVVAELAKIDNIVA
                     VKEASGDLAQVAEIAKLVPKDFAIYSGNDDTILPLLSLGGSGIISVLANICPKETHDL
                     VTKFFEGDIEGSKKLQLDMDALIAALFIEVNPVPVKTAMNILGFNVGDLRLPLAEMEE
                     TNLNVLKQELTNFGFKF"
     gene            1413..2414
                     /locus_tag="PC512_003055"
     CDS             1413..2414
                     /locus_tag="PC512_003055"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HDF2442785.1"
                     /translation="MKKVNVAIIGATGMVGRTFLKVLEERNFPIENLFLFSSSKSAGS
                     KVMFCGKEYIVEELKETSFTDRGIQIALFSAGGSISEKYAPIAASNGILVVDNSSQWR
                     MNPDVPLVVPEVNPEAIKNHKGIIANPNCSTIQAMVPLKALDDKYKIKRVVYSTYQAV
                     SGSGVKGVEDLEKGMNGNPTGFYPHQISYNCLPHIDSFTENGYTKEEMKMVNETMKIL
                     DNYDLKITATTVRVPVKNGHSESINVEFNNPFELDDLVKTLEEAPGVVVVDNPAKNEY
                     PTAVEFDDRDEVFVGRIRRDFSVDNGVNLWVVADNIRKGAATNAIQIAEMALSYDLV"
     gene            2531..3418
                     /locus_tag="PC512_003056"
     CDS             2531..3418
                     /locus_tag="PC512_003056"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HDF2442786.1"
                     /translation="MIFKGSAVALVTPFTKDNKVDFDKLGELVEYQIANGTDAIVSCG
                     TTGEANTMTDEEQLATIKYVVEKVNKRVPVIAGSGSNDTMHSVNLSQEAEKLGVDALL
                     IITPYYNKANKAGLKRHFETIANSVKLPIILYNVPGRTCVNISPSLIVELAKIDNIVA
                     VKEASGDLGQVAEIASLVPDDFAIYSGNDDTILPLLSLGGQGVISVLANVCPQETHDL
                     VAKFFEGDIEGSRKLQLGMDALIAALFIEVNPIPVKTAMNLLGFNVGDLRLPLAEMDP
                     ANLEVLKKELVNFGLKVNA"
     gene            3485..4234
                     /locus_tag="PC512_003057"
     CDS             3485..4234
                     /locus_tag="PC512_003057"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HDF2442787.1"
                     /translation="MLKVIATGYDGKMGKILADTIREDNELELVCVAARGLDSYEGDL
                     KIYEDMSTIVEEADVVIDFSHHSNLDNILSYVLKTKTPLVIATTGYNDDEMNKIREAA
                     KVIPVFQSYNMSLGVNVLVKLVKDAAKLLEGFDIEIIEKHHNRKVDAPSGTAVMIANA
                     IKEVLPNVENNYGRYGRSAKRQPNEVGIHAIRGGNIVGEHDALFAGDNEVLTISHQAQ
                     SRGIFASGSIAAAKYLVKQKPGFYNMDSMLG"
     gene            4458..5174
                     /gene="dapD"
                     /locus_tag="PC512_003058"
     CDS             4458..5174
                     /gene="dapD"
                     /locus_tag="PC512_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HDF2442788.1"
                     /translation="MVNLNDAYEIARYIKEVKKKTPVKVYVNTNSLHFQSTDKFKVFG
                     SNGSYIFVGDYEDIMEVLDKHGNDITDTHVEYDRRNSAIPLKNTLSEHARIEPGAIIR
                     DMVTIEKNAVVMMGAVINIGAVIGEGSMVDMNAVIGARGTLGKNVHLGAGAVVAGVLE
                     PPSATPVIVEDDVLIGANAVILEGVRIGKGAVVAAGAVVTTDVEAGAVVAGSPAKVIK
                     MKDEKTADKTKLMEDLRNLD"
     gene            complement(5626..6615)
                     /locus_tag="PC512_003059"
     CDS             complement(5626..6615)
                     /locus_tag="PC512_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HDF2442789.1"
                     /translation="MLKEEKTYQEKDAKVFNGVAALIMILLFLVVSIGIMVFGIVKLD
                     SGFTGIGSLMLILGLVFIVVDFILFFGLKMINPKEAIVLVLFGNYYGTIKKEGYYWVN
                     PFCSAINPAVSRINVSKSSSDEKVDISTNSRGKKVSLKTMTLNNEKQKVNDLLGNPII
                     IGVVVIWKVIDATKAVFNVDNYNTFLSIQCDSTIRNVSRLYPYDVSEDGDEKSLRGSS
                     QEIADRLKDELQSRVDIAGIEVCEVRITHLSYAPEIAAAMLQRQQAEAIIAARKKIVE
                     GAVSMVEMALTNLSENNVVTLDEERKAAMVSNLLVVLCGNKDAQPVVNSSSIY"
     gene            7055..7810
                     /locus_tag="PC512_003060"
     CDS             7055..7810
                     /locus_tag="PC512_003060"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HDF2442790.1"
                     /translation="MLKVIISGYNGTMGRVLAECVKKDNELELVCGVARSADEKGHHS
                     DTKLYKTMTDVTEKTDVIIDFSHHDTLEPILSYALKNNTPVVLATTGYDENDLNKIEE
                     ASKNIPILLSSNTSLGVNILIKLVKDASKMLEGFDIEIIEKHHNRKEDAPSGTATMIA
                     NAIREVLPESENTHGRYGRDCKRKPNEIGIHSIRGGNIISDHDVVFAGDNEVLTLSHH
                     SQSDEVFANGSIVAAKFLIGKQSGLYKMSDILG"
     gene            complement(8164..9840)
                     /gene="bclA2"
                     /locus_tag="PC512_003061"
     CDS             complement(8164..9840)
                     /gene="bclA2"
                     /locus_tag="PC512_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA2"
                     /protein_id="HDF2442791.1"
                     /translation="MSDISGPSLYQDVGPTGPTGATGPTGPTGPRGVTGATGANGITG
                     PTGNTGATGANGITGPTGNMGATGPNGTTGSTGPTGNTGATGANGITGPTGNTGATGA
                     NGITGPTGNKGATGANGITGSTGPTGNTGATGANGITGPTGNTGATGATGPTGLTGAT
                     GATGANGITGPTGNTGATGANGVTGATGPTGNTGATGPTGSIGATGATGTTGATGPIG
                     ATGATGADGEVGPTGAVGATGPDGLVGPTGPTGPTGATGANGLVGPTGPTGATGANGL
                     VGPTGATGATGVAGAIGPTGAVGATGPTGADGAVGPTGATGATGANGATGPTGAVGAT
                     GANGVAGPIGPTGPTGENGVAGATGATGATGANGATGPTGAVGATGANGVAGAIGPTG
                     PTGANGATGATGATGATGANGATGPTGATGATGVLAANNAQFTVSSSSLVNNTLVTFN
                     SSFINGTNITFPTSSTINLAVGGIYNVSFGIRATLSLAGFMSITTNFNGVTQNNFIAK
                     AVNTLTSSDVSVSLSFLVDARAAAVTLSFTFGSGTTGTSAAGYVSVYRIQ"
     gene            complement(10218..10757)
                     /gene="hpt"
                     /locus_tag="PC512_003062"
     CDS             complement(10218..10757)
                     /gene="hpt"
                     /locus_tag="PC512_003062"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HDF2442792.1"
                     /translation="MDIETKKWEVLYSEEKIKDKLRELGAIIEKDYKDKNLMVVSLLK
                     GSFIFCADLVRNINLPLRVNFMTTSSYGNNEESTGKVKVVSDVTTDIAGYDVLVVDDI
                     TDSALTMDFVLKHLKAKNPASLKCCVLLDKPSRRKVDLVPDYCGFEIEDKFVVGYGFD
                     FGDYYRNVPYIFNVTDEDR"
     gene            complement(11085..12392)
                     /locus_tag="PC512_003063"
     CDS             complement(11085..12392)
                     /locus_tag="PC512_003063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine dehydratase subunit alpha family protein"
                     /protein_id="HDF2442793.1"
                     /translation="MRDIRKELVEMLKAEVKPAVGCTEPVALALACAKAKELLGEEIV
                     ENRMLVSPSIYKNGMCVGIPGTERLGLKIAAALGIVGGHSENGLSVLETLTKEEVKIA
                     EDYMDNTPLSITPADTREKVFIEVVLKGKNHIAKVRIRTKHDNFTFLEKDGEVLLDNE
                     PKVSASNDAAEKAESLMDTVTIQELIKNVEGIDFKDIEFLLDGVKMNEEMAEYGLKQK
                     TGIGVGYGIKKSIEEGLLGNDVINYAMMLTAGASDARMAGVKMPVMSSNGSGNHGLTA
                     ILPIVAYNKKFPQSDERLAKALAISHLVTGYIKNYTGRLSAVCGCGVAASTGATAGIS
                     WLMNGTEKQIEGAIENMIADLSGMICDGAKAGCALKLSSAASAAIQSAIIAKQDCFVP
                     PLNGIVGSSVEQSIQNLGRVSDKGMSITDEIILNVMNDMNKVD"
     gene            complement(12817..14592)
                     /locus_tag="PC512_003064"
     CDS             complement(12817..14592)
                     /locus_tag="PC512_003064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2442794.1"
                     /translation="MMIMIGLEYIKSDIQNIAEAIVSVLNIDVTIVNKELFRIAGTGV
                     YIDKIGEKVDKYTAFKKSLTEQITILIDDPKSSDICRECYKSGACVEFAEVCCPIICD
                     GVSHGVIGLIAFTKEQAQIIENNKSGLINFLGKMADLISNKLKAQIKTYELELEKKKL
                     ETLLNNMDKAVVSIDVDGKIDKYNSKFKELFNIKDSITGKNIFVELDFIKKPSINNFK
                     KDKSCSFFYKRYGYDSKGIYNINKIVLKNELKGYVIDFIDKRDAIKNYNKMNKDYRIK
                     LENIIGESVAIRNSKKEALIASKSTSTVLITGESGTGKELFARAIHNHSNRVDNPFIA
                     VNCAAIPDNLLESELFGYEEGAFTGAKKGGKLGMFEVAHKGSIFLDEIGDMSLHLQSK
                     LLRVLQEKELNKIGSKSNVSIDVRIIAATNKDLEKMVQNGTFREDLYYRLNVIPIKLP
                     SLRERKEDIPLIIKHMVKEYSKKLDKNVIDIDSRVVDAMMEYKWPGNIRELQNIIEYS
                     VNMSSSSIITMNVIPQKIKNTSVEELEVKSDRIIPLDELEKIEIIKALNKYKDYKKDK
                     ELTAKALGISRATLYRKIEKYNIIS"
     gene            complement(14589..14726)
                     /locus_tag="PC512_003065"
     CDS             complement(14589..14726)
                     /locus_tag="PC512_003065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442795.1"
                     /translation="MEINYELIIIVMLFVILMSIQFTLNKIYLILKEIRQILMLKKNK
                     E"
     gene            complement(14804..15373)
                     /locus_tag="PC512_003066"
     CDS             complement(14804..15373)
                     /locus_tag="PC512_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDF2442796.1"
                     /translation="MKSILCQINKQPVKAKYTSDELECFLDTIEYNVGDKILLVGHIG
                     NLGKRLRGLGTSVTILENSNYEDVCYSLVYNENCNVVKGKLEFLPFDDNQFNKIIIVD
                     QFNVITDCEKASSEIQRVLKGNGEVILEDLNLKNLKVKLNYLKHKFCGSVAKIHYPHE
                     VFNIFSRLNFDGMIKESNKLKYIYVGKRR"
     gene            complement(15557..16192)
                     /locus_tag="PC512_003067"
     CDS             complement(15557..16192)
                     /locus_tag="PC512_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDF2442797.1"
                     /translation="MIAVKDENNVVNLRGELDNKLEFSHEIFGEKFYNMKIKINRLSD
                     SFDILPMTVSERLLQDIDLDKQNLVNVVGQLRSYNKTLNNKNRLVLTVFVREIKSIDE
                     ENKDPNSIFLDGYVCKEPVYRKTPLGREITDLLVAINRPYNKSDYIPSIVWGRNAKFA
                     KNLKVGDRIQLWGRVQSREYEKKIDENNVVKKMAYEVSISKIKKLDENNNE"
BASE COUNT         5388 a         2721 c         2240 g         6156 t
ORIGIN      
        1 taaacagtta agatattaac tatacctatt aaaattaatt aatttgtact ataattatta
       61 ttgtacttaa aaaattaaat ttagataaaa aaggagattt gattatatgt tatttaaagg
      121 ttctgctgtt gctttagtta ccccatttac agaggataat aatgtcaact ttgaaaaatt
      181 aggtgaatta atcgaatatc acattgagaa tggcacagat gcactagttg tttgtggaac
      241 aacaggtgag gcgactacta tgagtgaatc tgaaattttt gctgtaataa aatatacagt
      301 tgaaaaagtt aataagagaa tacctgttat agcaggtact ggttcaaaca atactatgtt
      361 gtctgttcat atgagtcaag aagctgaaaa attaggggtg gatggtcttt taataataac
      421 tccttactat aataagacta atgagaaagg tcttaaactt cactttgaaa caatagcaaa
      481 tagcgttaag ttgccaatta ttttatacaa cgtaccagga agaactaaag tgaatataaa
      541 gccatctgtt gtggctgaac ttgctaaaat agataatata gttgctgtga aggaagcaag
      601 tggagactta gctcaagttg cagaaatagc taaattagta cctaaagact ttgctatata
      661 ctccggtaat gatgatacta tactaccact attatcatta ggtggaagtg gtattatctc
      721 tgtacttgct aacatatgtc ctaaagaaac acatgattta gtaactaaat tctttgaagg
      781 tgatattgaa ggctcaaaaa aattacaact tgatatggat gctttaattg ctgctttatt
      841 tatagaagta aatccagttc ctgttaaaac tgccatgaac attttaggtt ttaatgttgg
      901 tgatttaaga cttcctctag ctgaaatgga agaaactaat cttaatgtgt taaaacaaga
      961 attgacaaat tttggattta aattttagca atatttatat aaataagttg attttttctt
     1021 aaatatgtat tattattaga ataatcaaat tttaatatcc tattaaccta gggtagaggt
     1081 agctgtaact aagagtatcc aatagtagct ggcaggtgtt aatgattgga aaaaggattt
     1141 acagccgaag aaaatatttc ttgcaataat attttctggg attgcacata acatgtgtaa
     1201 tactgtcact tatttttgta ggtgatgagc tacagggttt actttgagtg ataaattaga
     1261 cgtacaaagt atacctttgt acgttttttg tatataatta aagttgttaa tataatatta
     1321 aagtttttgg atatataaaa atattaacat atcttacttg tataactaaa ataaaataat
     1381 gttttaataa tttaaaattg gggtgaattt atatgaaaaa agtaaatgta gcaataattg
     1441 gtgctactgg aatggtaggt agaacatttt taaaagtatt agaagaaaga aattttccaa
     1501 tagaaaatct atttttattc tcttcttcta aatcagctgg ttctaaagta atgttttgtg
     1561 gtaaagaata tatagtagaa gaattaaagg aaacttcatt tactgataga ggcatacaaa
     1621 tagcattatt ctctgctggt ggaagtatta gtgaaaagta tgctccaata gctgcttcaa
     1681 atggaatctt agtagtagat aactctagtc aatggagaat gaatccagat gtgcctttag
     1741 tagttcctga ggttaatcca gaagccataa aaaatcataa gggtataata gctaatccta
     1801 actgctctac tatacaagct atggttcccc ttaaagctct tgatgataaa tacaaaatta
     1861 agagagttgt ttactctact taccaagctg tatctggttc tggtgttaaa ggtgttgaag
     1921 atttagagaa aggaatgaac ggtaatccta ctggattcta ccctcatcaa atctcttaca
     1981 actgtcttcc tcatatagat tcattcactg aaaatggata cactaaagaa gaaatgaaaa
     2041 tggtaaatga aactatgaaa atacttgata actacgattt aaaaataact gcaactactg
     2101 taagagttcc agtaaaaaat ggtcatagtg aatctataaa tgttgagttt aacaatccat
     2161 ttgagttaga tgatttagta aaaacacttg aagaagctcc aggtgttgta gtagttgata
     2221 atcctgctaa aaacgaatat ccaactgctg tagaatttga tgatagagat gaagtatttg
     2281 ttggaagaat aagaagagat tttagtgttg ataatggtgt aaatctttgg gttgttgctg
     2341 ataatataag aaaaggtgct gcaactaacg caattcaaat agctgaaatg gctttatcat
     2401 acgatttagt ataatataca aacttgtata aatatataat tttgtaaaat attaatagta
     2461 actcaaaaac aagcattaga agtaactgta atataaaaca caaaaataaa aaagagggga
     2521 ttgattttat atgatattta aaggttctgc tgttgctcta gttacaccat ttacaaagga
     2581 taacaaagtt gattttgaca aattaggtga attagttgaa taccaaatag ctaatggtac
     2641 tgatgctata gtatcttgtg gtactactgg tgaagctaat actatgactg atgaagaaca
     2701 acttgctact attaagtatg ttgttgaaaa agttaataaa agagttcctg ttatagctgg
     2761 aagtggttct aatgatacta tgcactcagt taacttaagt caagaagctg aaaaattagg
     2821 agtagatgct ctattaataa taacacctta ttacaataaa gctaataaag ctggacttaa
     2881 gcgtcatttt gaaacaatag ctaacagtgt taaacttcca attatacttt acaatgtccc
     2941 tggaagaact tgtgtaaata taagtcctag ccttatagtt gaacttgcta aaattgataa
     3001 catagttgct gtaaaagaag ctagtggaga cctaggacag gttgcagaaa tagctagttt
     3061 agttccagat gactttgcta tctactctgg taatgatgat actatacttc ctttattatc
     3121 tttaggaggt caaggagtta tatcagtact tgctaatgtt tgccctcaag aaactcacga
     3181 tttggtagct aaattctttg aaggcgatat tgaaggttct agaaaattac aacttggtat
     3241 ggatgctcta atcgcagctt tatttataga agtaaatcct ataccagtta agactgcaat
     3301 gaatttattg ggattcaatg ttggagattt aagattacct ctagcagaaa tggacccagc
     3361 aaatttagaa gtattaaaga aagaattagt taactttgga ctaaaagtta atgcatagta
     3421 aagattaatg catggtaaaa agtaagtttg gtcaaaagtt agcccttaat cataggagga
     3481 aattatgtta aaagttatag caactggtta tgatggaaaa atgggtaaga ttttagccga
     3541 tactataaga gaagataatg aattagaatt ggtttgtgtt gcagctagag gtctggatag
     3601 ctatgaaggc gaccttaaaa tttatgaaga tatgagtact atagttgagg aagctgatgt
     3661 agttatagat ttttctcatc actctaattt agataatatc ttatcttacg ttttaaagac
     3721 taaaacacct ttagtaattg ctactactgg atataatgat gacgaaatga acaaaatacg
     3781 tgaagcggct aaagttattc ctgtattcca atcatataat atgtctcttg gtgtaaatgt
     3841 attagtaaaa ttggttaaag atgcagctaa attactagaa ggatttgata tagaaataat
     3901 agaaaaacat cacaacagaa aagtagatgc cccaagtggc acagctgtta tgattgctaa
     3961 cgctataaaa gaggttttgc caaacgttga aaataattat ggtagatatg gtcgtagtgc
     4021 aaaaagacaa ccaaatgaag ttggtattca tgctataaga ggtggaaata ttgttggcga
     4081 acatgatgct ctatttgctg gagacaatga ggttcttaca ataagccatc aagctcaatc
     4141 tcgtggtatc tttgcaagtg gttctatagc tgctgccaaa tacttagtta agcaaaaacc
     4201 aggattttat aatatggaca gcatgttggg ataatagtat aaatataata atacacaata
     4261 taaattaaac atatacaata tatatataat aatatgcaat acaaatcaaa catatataat
     4321 aaatttattt aatactatgt ctatacaata aaagctaact aaaataaaat ataaataata
     4381 agaagtaagt atatactaaa attgacaaat aagtatataa taaaagaaat ataatgaaat
     4441 acaaggagaa ttaacaaatg gtaaatttaa acgatgctta tgaaatagca aggtatataa
     4501 aagaagttaa aaagaaaaca cctgttaagg tatatgtaaa tactaactct ttacacttcc
     4561 aatcaactga taaatttaag gtatttggaa gtaatggttc ttatatattt gtaggtgact
     4621 atgaggatat aatggaagta ttagataaac atggaaatga tataacagat actcatgtag
     4681 aatatgatag aagaaattct gctattcctc taaaaaatac tttaagtgaa catgcaagaa
     4741 ttgagccagg tgcaataata agagacatgg ttactataga aaaaaatgct gttgtaatga
     4801 tgggagctgt tataaatata ggagctgtta ttggtgaagg ttctatggta gatatgaatg
     4861 ctgttattgg agctagagga actcttggta aaaatgttca cttaggtgct ggtgctgttg
     4921 ttgctggtgt tttagagcca ccttctgcta ctcctgttat agttgaagat gatgttttaa
     4981 taggagctaa tgcagttatt cttgaaggtg ttagaatcgg taaaggtgct gttgttgcag
     5041 ctggtgctgt tgtaactact gatgtagaag ctggtgccgt tgttgctggt tctcctgcta
     5101 aagttataaa aatgaaagat gaaaaaacgg ctgacaaaac taagcttatg gaagacctta
     5161 gaaatttaga ttaattaaat agtactatgc tattaattaa acaataatat actaatttaa
     5221 aaaattaatt aaaaaggtgt ctctgtgtga atttaattca ccagaggcac cctctttttt
     5281 acaatatttt tatcttttat ttataatcat tttatttttt tacaattctc ttattcattc
     5341 ttatatcatt tttatttctt gctgacaagt atttttattt ccttcaattt ttcaatatat
     5401 caatgtaata aactattaaa ctttttataa tttaataaag tgaaaaccat taatctttat
     5461 ataatttaat aaaatgaact actaaatttt ctatatatca atagaataaa ttattaaact
     5521 ttttataatt caataaagca aaccattaat ctttatataa tttaataaaa tgaactacta
     5581 aattttctat atatcaataa aataaactat taaacttttt ataatttaat aaatagaact
     5641 gctgtttacc actggttgtg catctttatt gccacaaagc acaactaaca gattacttac
     5701 catagctgct ttacgttctt cgtccaaagt cacaacatta ttttcactta aattagtcaa
     5761 tgccatctct accatactta cagccccctc aacaatcttt ttacgtgctg ctattatagc
     5821 ctctgcttgt tgacgttgta acattgctgc tgcaatctct ggtgcataag aaagatgagt
     5881 aattctcact tcacacactt caattcctgc aatgtcaacc cttgattgta attcatcttt
     5941 taatctatct gctatttcct gactactacc acgaagagat ttttcatctc catcttcaga
     6001 tacatcatat ggataaagtc ttgaaacatt gcgaatagta gaatcacact gaatagataa
     6061 gaatgtatta taattatcca cattaaatac tgcctttgtt gcatctataa ccttccaaat
     6121 tacaaccact cctattataa ttggatttcc caataaatca ttgactttct gcttttcatt
     6181 attaagagtc attgttttta aagatacttt tttgcccctt gaattagttg atatatctac
     6241 cttttcatca gatgaagatt tcgatacatt aattcttgat actgctgggt ttattgctga
     6301 acaaaatgga ttcacccaat agtacccttc tttttttata gttccataat agttaccaaa
     6361 caaaactaga actatagctt ctttaggatt aatcattttt agcccaaaaa ataggataaa
     6421 atctactact ataaatacaa gtcccaaaat taacataagt gaacctattc cagtaaatcc
     6481 actatcaagt tttactatcc caaaaaccat gatacctatt gaaactacta aaaataataa
     6541 aatcattatc aaagctgcca ctccattgaa tacttttgcg tctttctctt gataagtttt
     6601 ttcttctttt aacatatcta tcactcccat ctcagtatat taagttaaga tatttctaat
     6661 ttaataataa cacttttaac aattaaattg ttgaatttaa aattaatact atatgtttat
     6721 atatttttta tacatcttta tgcatacatg tatttagtta ttttaatgta ttaatattaa
     6781 tttccaaata aatcatatga tatatgaata tggtatttca aaattaactt tttagttcat
     6841 ggggcactct ttttggtatg aagtcaaata tatttttatc atttaaacaa tgaaaaagaa
     6901 atttatctat attttgaaaa atccacttaa attttttaat gtaagataaa ttgtaagctt
     6961 attatcacta atattatttt atataaatta tattagtgat aaaataaact tatagaaata
     7021 taacaaattt ttattaattt cataggagga atttatgttg aaagttataa ttagtggcta
     7081 taatggaaca atgggaagag ttttagcaga atgtgtaaaa aaagataatg aattagagtt
     7141 ggtttgtggt gtagctaggt ctgctgatga aaaaggtcat catagtgata caaagcttta
     7201 caaaacaatg actgatgtaa ctgaaaaaac tgatgtaatt atagactttt cacatcatga
     7261 tactttagag ccaatattgt catatgctct aaaaaataat acacctgtag tattagctac
     7321 tactggatat gacgaaaatg acttaaataa aatagaagaa gcatcaaaaa acattcctat
     7381 attattatca tcaaatacat ctcttggagt aaatatatta ataaaattag ttaaggatgc
     7441 ttcaaagatg ttagaaggtt ttgatattga aatcatagaa aaacatcaca atagaaaaga
     7501 agacgcccct agtggaactg ctactatgat agctaatgca attagagaag tcttgcctga
     7561 aagtgaaaat acacatggta gatatggtag agattgtaaa agaaaaccaa atgaaattgg
     7621 aatacactct ataagaggtg gcaatataat cagcgaccat gatgttgtat ttgcaggtga
     7681 taatgaagtt cttacattaa gccatcattc tcaatctgat gaagtatttg caaacggctc
     7741 tatagttgca gctaaatttt taattggtaa gcaatctggg ctttataaaa tgtcagatat
     7801 attaggataa gttttgtaca taataaatct caatctattt aggtattcat attcatcaat
     7861 ttgaatatct aattgattga gatttctatt ctaaaagttt ataaatttta tgcttacctt
     7921 ttaaatataa tcatttttct taaatattat cttatttatt ggtatatgaa atcatattgt
     7981 ttattatttt atagtctttt catcatataa acctattaaa tattatccta tttattggta
     8041 tatgaaatca tattgtttat tattttatag tcttttcatc atataaacct attaaatatt
     8101 attctattta ttggtatatg aaatcatatt gtttattatt ttataatctt ttcatcatat
     8161 aaactattgt attctataaa ctgatacata tccagctgca gaagtacctg tcgtgcctga
     8221 accaaatgta aaacttaaag taacagctgc tgctctagca tcaactaaaa agcttaaact
     8281 tacacttaca tctgatgaag taagtgtatt tactgctttt gcaataaagt tattttgagt
     8341 tactccatta aagttagtag taattgacat aaatcctgca agtgaaagtg tggcacgtat
     8401 accgaaagat acattgtata tccctccaac tgcaagattt atagtactac ttgttggaaa
     8461 agttatatta gttccattta taaatgatga attaaatgtc actaatgtat tattcactaa
     8521 acttgaagag gacactgtaa attgtgcatt gtttgctgct aacactcctg ttgctcctgt
     8581 cgctccggtt ggacctgttg ctccatttgc tccggttgct cctgtcgccc ctgttgctcc
     8641 tgtcgctcca tttgctccgg ttgggcctgt tggtcctatc gctcctgcta ctccatttgc
     8701 tcccgttgct cctactgctc ctgttgggcc tgttgctcca tttgcccctg ttgctcctgt
     8761 cgctcctgtt gctcctgcta ctccattttc tcccgttgga cctgttggac ctattggacc
     8821 tgctactcca ttcgctcccg ttgctcctac tgctcccgtt gggcctgttg ctccatttgc
     8881 ccctgttgct cctgtcgctc ctgttggacc tactgctcca tctgctcccg ttgggcctgt
     8941 tgctcctact gctcccgttg gacctattgc cccagctact cctgttgctc ctgtcgctcc
     9001 tgttggacct accaaaccat ttgctccggt tgctccggtt gggcctgttg ggcctaccaa
     9061 accatttgct ccggttgctc cggttgggcc tgttgggcct gttggaccta ccaaaccatc
     9121 tggacctgtt gctcctactg ctcctgttgg acctacctct ccatctgctc ctgttgctcc
     9181 tgttgctcct attgggcctg ttgccccagt tgttcctgtt gctccagtcg ctcctatact
     9241 tcctgttgga cctgttgctc ctgtatttcc tgttgggcct gtagcacctg ttactccatt
     9301 tgctccggtt gctcctgtat ttcctgttgg tcctgttatt ccatttgctc cggttgctcc
     9361 tgttgctcca gttagtccgg ttggtcctgt tgctcctgtt gctcctgtat tccctgttgg
     9421 acctgttatt ccatttgctc cagtcgctcc tgtatttcct gttggtcctg tagaacctgt
     9481 tattccattt gctccggttg ctcctttgtt tcctgttggt cctgttattc catttgctcc
     9541 ggttgctcct gtattccctg tcggacctgt tattccattc gctccagtcg ctcctgtatt
     9601 tcctgttggt cctgtagaac ctgttgttcc atttggtcca gtcgctccca tatttcctgt
     9661 tggacccgtt attccattcg ctccagttgc tcctgtattt cctgttggtc ctgttattcc
     9721 atttgctccg gtcgctccag ttacacctct aggccccgtc ggtcctgttg gaccagtagc
     9781 acctgttggc cctgttggac ctacatcttg atataaactt ggacctgaaa tatcactcat
     9841 ataattaatc ctcctttttt aaagttagag taatactcta taaatattga gtattactct
     9901 atataattat atgaatcgac aatttcttat gtgataatgt atctatttgc ttatatcaac
     9961 atatatgctt tgattcttaa atttcattac ttttttgtaa aatcttttac aattattagt
    10021 actcttttac aattattaat acaattaaaa aactcatttc ccatcaatta tttaaaattt
    10081 ttttattatg ctataaaaaa tagataatta aattgcataa aattaattta atactacttt
    10141 aattactttt taaataaaaa aacctcaaca cgattaataa aaatcatatt aaggcatcca
    10201 caaaattata taattgctta tctatcttca tcagtaacat tgaatatata aggaacattt
    10261 ctataataat caccaaaatc aaacccatat ccaaccacaa acttatcttc tatttcaaat
    10321 ccacaataat ctggcactaa atcgactttt cttctgcttg gtttatccaa aagaacacag
    10381 cattttaaac tagcaggatt tttagctttt agatgtttta acacaaaatc catagtaagt
    10441 gcagaatcag taatatcgtc tacaaccaaa acatcatatc ctgctatatc agtagtcaca
    10501 tctgaaacta ctttaacctt tccagtactt tcttcattgt ttccataact agatgtagtc
    10561 ataaaattaa ctctaagtgg taagtttata tttctaacta agtctgcaca aaatataaag
    10621 ctacctttta atagagaaac taccataaga tttttatctt tataatcttt ttctataatt
    10681 gctcctaatt cccttaattt atctttaatt ttttcttctg aatacaatac ttcccatttt
    10741 tttgtttcta tatccataaa aagacctcca attgtaataa tccttcttaa ttttataaga
    10801 gattgctcac tttttcaata ctcttattca atattagtca atattattga gtttttatgt
    10861 tcattcaaca attattaaca atgtatctta tattttaagt agttcatata tccacactaa
    10921 attacatact atatatttta gacaaaaaaa gaaaaaactt gcattaacaa gttttttcta
    10981 ttatacataa atttatacat aatcatattt tattagaggg tactaattaa atttatttat
    11041 gctatttttg ttatacctca taatacaaaa catattataa agtactagtc aactttattc
    11101 atatcattca ttacatttaa gattatctca tctgttatag acataccttt gtcacttact
    11161 ctacctaagt tttgtatact ttgctcaaca cttgaaccaa ctataccatt tagtggtggt
    11221 acaaaacaat cttgcttagc tattatagca ctttgtatag ctgcagatgc tgcagaagat
    11281 aattttaatg cacaaccagc tttcgcaccg tcacatatca ttccacttaa gtcagctatc
    11341 atattttcta tagctccttc tatttgcttt tcagtaccat tcataagcca agagatacca
    11401 gcagttgctc cagtagaagc agcaacacca catccacata cagcagataa tcttcctgta
    11461 tagttcttaa tataaccagt tactagatga gatatagcta aagcttttgc tagtctttca
    11521 tcagattgtg ggaatttttt attataagca acgattggaa gaattgctgt taatccatga
    11581 tttccacttc catttgaact cataacaggc atttttaccc ctgccattct tgcatctgaa
    11641 gctccagcag ttaacatcat tgcataattt ataacatcat tacctaaaag accttcttct
    11701 atagactttt taattccata tcctacacca ataccagttt tttgttttaa tccatattca
    11761 gccatctctt cattcatttt tactccatct agtaaaaatt ctatatcttt aaaatcaatt
    11821 ccttctacat tttttattaa ttcttgtata gttactgtat ccattaaact ttcagctttt
    11881 tctgccgcat catttgaagc tgatactttt ggttcattgt ctaataatac ttctccatct
    11941 ttttctaaga acgtaaaatt atcatgttta gttcttattc tcactttagc aatatgattt
    12001 tttcctttta acacaacttc tataaatact ttctctcttg tatcagcagg tgttattgat
    12061 agtggagtat tatccatata atcctcagct attttaactt cctcttttgt tagagtttct
    12121 aacacactta atccattttc agaatgtcca cctactatac ctagagctgc tgcaattttt
    12181 aatcctaatc tttcagtacc tggtatacct acgcacatac catttttata aatactagga
    12241 ctaactaaca tacgattttc aactatttct tctcctaata attcctttgc ctttgcacat
    12301 gctagagcta aggctactgg ttcagtacac cctactgctg gtttaacttc tgcctttaac
    12361 atttccacta attcttttct tatatctctc attatatata aacctcccaa ttaagtttag
    12421 atttagtact caaataatta attaaataat ttcttatcta tatttatagc aaaatacatg
    12481 ccatattttt tatatctttt tatattttta gtcttatatt ctataaccat tggtatgact
    12541 gcctctattt atgtattttt tttatttgta tagagtattt atattcttta aaatggagaa
    12601 acatatgaca atttcgcaaa aagacaaaaa aaagtctcaa aatgagattc tatatcattt
    12661 tgagacggct caaatatatt attttttaac ttataaaaac cattttttaa ttcataaaaa
    12721 aagattctgc aaaacactta tagtataagt ttaaagcttt ctttaaagtt atgaatttag
    12781 aaaaatttaa attttatata gctttttatt atattactat gaaattatat tgtatttttc
    12841 aatttttcta tataatgtag ctcttgatat tccaagtgct ttagctgtta attctttatc
    12901 ttttttataa tctttgtact tatttaaagc ttttattatc tcaatcttct ctagttcatc
    12961 aagtggaatt atcctatcgc ttttaacttc taactcttct acagaggtat tcttaatttt
    13021 ttgaggaatt acattcattg taattattga agaagaagac atattcacac tatattcaat
    13081 aatattctgc aactctctta tattccctgg ccacttatat tccatcatag catcaacaac
    13141 cctgctatct atgtcaataa catttttatc taattttttt gaatactctt taaccatatg
    13201 cttgattata agtgggatat cttcttttct ctctcttaaa cttggtaatt ttataggtat
    13261 aacatttaat ctatagtata aatcttctct aaaagtgcca ttttgaacca ttttttctaa
    13321 atctttattt gtagcagcaa taattcttac atctattgaa acatttgatt tacttccaat
    13381 tttattaagt tccttttctt gtaatactct caataacttt gactgtaaat gcaaactcat
    13441 atctcctatt tcatctaaaa atatacttcc cttatgagct acttcaaaca ttccaagctt
    13501 tccacctttt ttagctccag taaaagctcc ctcttcatat ccaaataatt cactttctaa
    13561 taaattgtct ggtatagcag cacagtttac agctataaaa ggattatcta ctctattgct
    13621 atggttgtgt atggctcttg caaatagctc cttacccgtt ccactttccc cagtaataag
    13681 tactgttgat gttgatttag aagctattag ggcttccttt ttagaatttc ttatagctac
    13741 actttctcca attatgtttt ccaattttat tctataatct ttattcatct tattgtagtt
    13801 ttttatagca tctcttttat ctataaaatc aataacatat ccctttaact cattttttaa
    13861 tactatttta ttgatgttgt atattccctt cgaatcatat ccgtatcttt tataaaaaaa
    13921 actacaggat ttgtctttct taaagttatt tatagaaggt ttctttataa aatctaattc
    13981 gacaaatatg tttttgccag ttatactatc ctttatattg aaaagctctt taaattttga
    14041 attatattta tcaatttttc catccacatc aatagacaca acagctttgt ccatattgtt
    14101 taacagtgtc tctaattttt tcttttctaa ttcaagctca taagttttaa tttgagcttt
    14161 taatttatta gatattaagt ctgccatttt gcctaaaaag tttataagac cacttttatt
    14221 attttctata atctgtgctt gttcctttgt aaaggctata aggcctataa caccatgaga
    14281 gactccatca catataatgg gacaacacac ctctgcaaac tctacacaag ccccactttt
    14341 atagcattcc ctacatatat cactactctt tgggtcatca attagtattg taatctgctc
    14401 tgtaagtgat tttttaaaag ccgtatattt atctactttc tcacctattt tgtctatata
    14461 tactcctgta cctgcaatcc taaataactc cttatttact atagttacat ctatattgag
    14521 tactgatact atagcttcag ctatattttg aatatcagat tttatatatt ctaaacctat
    14581 cataatcatc attccttatt tttctttaac ataagtattt gtcttatttc tttaagaatc
    14641 aagtatatct tatttaaagt aaattggatt gacatcagga ttacaaagag cataacaatt
    14701 attattaact cataatttat ttccatctaa acatctcctt ataacaaaag actaggctta
    14761 acctagtctt ttatattata tccatattta tattttaact catttatctt ctttttccca
    14821 cataaatata ttttaattta tttgactctt taatcatacc atcaaagttt aatcttgaaa
    14881 atatattaaa tacttcatgt ggatagtgaa tctttgcaac agaaccacaa aatttatgtt
    14941 taagatagtt taacttaact tttaaattct ttaaatttaa atcctctaat ataacctctc
    15001 cattgccctt taacactctt tgtatttcag atgaagcttt ttcacaatct gtaataacat
    15061 taaattggtc aactattatt atcttgttga actgattatc atcaaatggt agaaactcta
    15121 acttaccttt aactacattg caattttcat tatacactag agaataacag acatcttcat
    15181 aattactatt ctccagtata gttacagaag ttccaagacc tctcaatctc ttgcctaggt
    15241 ttcctatatg accaacaagc aatattttat cacctacatt atactcaatt gtatccaaaa
    15301 aacattctaa ttcatcagat gtatatttag ctttaaccgg ctgtttattt atctgacata
    15361 atatgctttt cacaatgctt cacctcttca tttcctcaat tataaattat gtacagatta
    15421 cattataata aatggcgagc aactattcaa gagatatttc attagtattt ttttaaacaa
    15481 tctttataca ttttaatatg atattatacc aaatttatta ggattttatt cataaaaatc
    15541 agtctatttt ttatgtttat tcattgttat tttcatccaa tttttttatt ttcgatatgg
    15601 atacttcata tgccattttt ttgaccacat tattttcatc tatttttttc tcatattctc
    15661 tactttgaac cctaccccaa agctgtattc tatcaccaac ctttagattc tttgcaaatt
    15721 tagcatttct accccaaact attgatggta tataatcaga tttattataa ggtctgttta
    15781 tagcaactaa taaatcggtt atttcccttc ctaaaggtgt cttcctatac acaggttcct
    15841 tacatacata tccatctaaa aatatactat tagggtcttt attttcctcg tctatgcttt
    15901 ttatttctct gacaaacact gtaagcacta atctattttt attatttaat gttttgttat
    15961 atgatcttaa ttggcctacg acattgacta aattttgttt atcaaggtca atatcttgga
    16021 gaagtctttc tgatacagtc attggaagta tatcaaaaga atcgcttagt ctgtttattt
    16081 ttattttcat attataaaat ttttctccaa atatctcatg gctaaattct agcttattgt
    16141 ctaactcccc tcttaagttt actacgttat tctcatcttt aacagctatc atattttatc
    16201 cctccacaat tgttaattct tatatttctg gtatcagctt atataataaa tatatttata
    16261 agggatgtat tttattacaa atctttgatt gctgtttaaa agtttttatt tagttataaa
    16321 tttcatttaa tatttcactt ttataattat aaaattatta tctttttgta ccacatatac
    16381 taattaaact acctatttca gttttgtatt aattataaaa atcctattat atagttaata
    16441 agtcatatat aacttaaatt tattcactct atataagcaa cttcaacgaa ttaaatttat
    16501 tcaaa
//
LOCUS       DAMJVG010000086        16411 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.087, whole genome shotgun sequence.
ACCESSION   DAMJVG010000086 DAMJVG010000000
VERSION     DAMJVG010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16411)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16411)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16411
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.087"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            112..1485
                     /locus_tag="PC512_003068"
     CDS             112..1485
                     /locus_tag="PC512_003068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2442798.1"
                     /translation="MNEILENIDEGVHFVNKDGKTIIYNNSVQKMEKMNRHDILTNSF
                     FDIVNKMKINRSTLLEVLEKREVIKDNIQKYLDKNGKEITAINTTIPIDIKGEFVGAL
                     EISKNMTTIENLLNRNYKKNLVNKVSIRQKKGYEFDDILGESNLIKEAIAKSKKACKS
                     DASVFIYGETGTGKELFSQSIHYGSNRRNYPFIAQNCAALPESLFEGILFGTSKGGFT
                     GAIDRPGLFEQANKGTLLLDEINSMPIMLQAKLLRVLQEGYVRRVGGTKDIPIDVRII
                     ATTNESPKVILNEHKMRKDLYYRLNIIHIKIPPLRDRKEDIPLLCKKFISKYNKKLNK
                     KVVGISDEAIKILKNYDWQGNIRELENIIYCTMSMMEDEVQIETSMINLNDYYTLKEN
                     KESNNYSLNDLEDKTLSKIISEIEEKYIYESLEKASYNITKAASILGMNRQNLQYKIK
                     KYNIKIL"
     gene            1741..2808
                     /locus_tag="PC512_003069"
     CDS             1741..2808
                     /locus_tag="PC512_003069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-binding protein"
                     /protein_id="HDF2442799.1"
                     /translation="MRKVRVGIWGFGAMGIGMANMILKKEGIEIVSVCSRSTSGKSMY
                     DVLGIERGERPEVIINKNYEEVFREKSVDVVLLATDSFTKKAFDKINFLLNRKINVIS
                     TAEQMAYPQADDADLAKKMDEVAKENGVSILGTGINPGFVLDLLVLALSGTCEEVTSI
                     KAKRVNDLSPFGKSVMVEQGVGVTREEFIKGVEDKTIAGHVGFVESINMIADGLGWKL
                     DKIEQTKEPIMTTVDRKSKYGEALAGNVAGCRQCGYGYVNGEVLIEMEHPQQIIPEAE
                     GIKTGDYVSIKGIPNIDLQINPEIPGGVGTYAMIVNSIPLIINARPGLKTMLDIPVPR
                     AIMGDIRNQIEVELEEESKAN"
     gene            2929..3237
                     /locus_tag="PC512_003070"
     CDS             2929..3237
                     /locus_tag="PC512_003070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-ketopentanoate thiolase"
                     /protein_id="HDF2442800.1"
                     /translation="MDAKINDWVIIHNIVLTPEERAPQVPEDTKKVSLEMWVKGFIQS
                     DASIGDLVEVKTITGRLVKGNLLKINPYYTHDYGKCIPELLQIGIQAKEILFGGVYNE
                     "
     gene            3230..4660
                     /locus_tag="PC512_003071"
     CDS             3230..4660
                     /locus_tag="PC512_003071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent lyase/thiolase"
                     /protein_id="HDF2442801.1"
                     /translation="MNNSTSMKDMSYQAVMGRNNEIMKNAIGLDYSSFEQEGIGFDYE
                     KMMSETGYTLQDIEAIQSQYAVGNTPLIELKNLTKLARKCAKEGKGARIFVKDEAMNA
                     SGSFKARRAATAVYHAKQMGYKGVIAATSGNYGAAVASQAAMQGLKCIIVQECYDSNG
                     VGQPEIIEKARKCEAYGAEVVQLTVGPELFYTFLVLLEETGYFNASLYSPFGIAGVET
                     LGYELAIQFREKYKKDPDIVVCTNAGGGNLTGTARGLIKAGSINTKVVGASVDLKGLH
                     MASDNQFNKKSFTTGHTGFGIPYCTWPDRSDVPRSAARPLRYMDRYVLVKQGEVFYTT
                     ELLAQLEGIERGPAGNTSLAAAFSLAQELDEDKAIVVQETEYTGAGKHICPQLTFARE
                     NGIDIKFGNPREEIAGVNLILPERPELLKCVDIDMNKIRKSFIKNCISNNHIDNIDKL
                     SNRDIEFLMEEVKSSRDFVVDVLNNL"
     gene            4738..5112
                     /locus_tag="PC512_003072"
     CDS             4738..5112
                     /locus_tag="PC512_003072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine aminomutase subunit alpha"
                     /protein_id="HDF2442802.1"
                     /translation="MKKREDDFEVRRKHLQELSDDELKERFWSLATQIVEPMIELGKK
                     NTTPSIERSVLLRMGFSSLEVKPILEGVMERGLIGKGAGHVVYKLAKSKNITVREAGL
                     LLVKGEYWDEVTCLFREGVESC"
     gene            5106..7310
                     /locus_tag="PC512_003073"
     CDS             5106..7310
                     /locus_tag="PC512_003073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892628.1"
                     /note="Presence of a B(12) (cobalamin)-binding domain
                     implies dependence on cobalamin itself, in one of its
                     several forms, or in some unusual lineages, dependence on
                     a cobalamin-like analog; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-dependent protein"
                     /protein_id="HDF2442803.1"
                     /translation="MLKENKKLDIDYILKDLDKYKPKRRGWVWREHLENLEMGPFKYK
                     DCTKPLKKSVGLPSSKYFNNIDPQPSPVITTEIASGRFEDDIRRMRMAAHHGADHLMV
                     IRTAGQSHFDGLIEGTPQGIGGVPITRKQVRAQRKALDFIEEEVGRPINYHSYVSGVA
                     GPEVAVMFAEEGVNGAHQDPQYNVLYRNINMVRSFVDACEAKKIMAFANIAQIDGAHN
                     ANATAREAWKVMPELMVQHALNSIFSEKIGIDKSNICLSTVPPTAPPAPCLKIDLPYA
                     VALRELFSDYKMRAQMNTKYMESSTREATVTHVLNLLTSVLTRADIQSTITPDEGRNV
                     PWHIYNIEACDTAKQALVGMDGLMDMIELKDVGELRDKARELKERAVLYMEEISEVGG
                     YFESVEQGFFVDSGNYPERNGDGISRKIKGGVGEGTVYEREEDYLAPVTAHFGYNNVA
                     QYDENAIDNPSMLIDGCTFENPDKIIYIDELDDFDNVENRLKESYEYRNGTKIKPEME
                     WCADGIIMITMMLPTDKRTAEFAALEFVKKMNLQEIEVISREVMHESEGTRIEVKGRV
                     PFDIDLNNLVIPEEPKVLTDEEIRADIEEKPMKIVSATVGEDEHSVGLREIIDIKHGG
                     IEKYGIECHYLGTSVPVEKLVDAAIELNADAILASTIISHDDIHYKNMKKLHDYCVEK
                     GIRDKVMIACGGTQVTPEIAVEQGIDAGFGRNSKGIHVATFLVEKRREMSNK"
     gene            7310..8719
                     /locus_tag="PC512_003074"
     CDS             7310..8719
                     /locus_tag="PC512_003074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate mutase L"
                     /protein_id="HDF2442804.1"
                     /translation="MENSKVSLKIDVLVAEIGSTTTVVNAFHDINTNNPIFLGQGQAP
                     TTVFEGGDVRNGLSGAIKDLANKLSVDDIEYNDMFATSSAAGGLKMTVHGLVYDMTVK
                     AAKEAALGAGAVIRQITSGRIKRTDLNKIKEINPNIILIAGGVDYGERDTAIYNAEMI
                     ASMNLGIPVIYAGNVENQEEIRLIFEDTNYKLYITENVYPKIDLLNIEPTRRIIQSVF
                     EEHITTAPGMKYIKEMVNENITPTPGAVMEASKLLYKNIGDLLTLDVGGATTDVHSVT
                     DGSDYINKILVNPEPTAKRSVEGDLGVYVNMKNIVEVIGKENLQSELSIDIDAVIENY
                     PPIPKSKEEILFVERLTKEAVVKAMLRHSGKIRNIYGTTGKVKIAEGKDLTEVRYIVG
                     TGGALTRLPSRIEILDNMLKYNKNNELLFPKEKTKILIDNDYIMASMGVLSKKYEEAS
                     LKLLLKSLNFEEERLCILG"
     gene            8704..9768
                     /locus_tag="PC512_003075"
     CDS             8704..9768
                     /locus_tag="PC512_003075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/ornithine racemase family PLP-dependent
                     enzyme"
                     /protein_id="HDF2442805.1"
                     /translation="MYPRLEIDIEKLKHNAKLISQMCHERNIKISFVTKSFCAQKEIV
                     EEICSEGIDHIADSRIQNLKNLQDINLPKILIRIPMLSELEEVINYCDISFNSELGTI
                     KKLNELCESKNIIHKIVLMFDLGDLREGYFYEEDFFNNVREIVRLKNIEIIGIATNLT
                     CYGAIIPSRENIGRLVSIAKRMEEKFGINLEIVSGGNSSSIHLLINNNMPEGITNLRI
                     GESILLGRETAYGENINGTYQDAFKLICQVVECKEKPSVPIGEIGVDAFRNKPVYEDK
                     GILKRAIIAIGKQDINIDSLIPIDTDIKILGASSDHMILDVSNTKYDYKLGDNLEFLL
                     TYGGIMSSSTSKYVSKKIIV"
     gene            9798..11219
                     /gene="nhaC"
                     /locus_tag="PC512_003076"
     CDS             9798..11219
                     /gene="nhaC"
                     /locus_tag="PC512_003076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HDF2442806.1"
                     /translation="MKERECRKASLFDAMIPITCLILFLSLGVLVYGSSPHVPLIGAA
                     AVAGLVAVYRLGFKWKELELSMFNSIKMAMQAILIIIIIGVLIGTWIVSGVVPCMIYW
                     GLKILSPNIFLVASTLVCAIVSLATGSSWSTMGTVGVALLGIGQSLGMPIGLIVGSII
                     SGAYFGDKLSPLSETTNLAPAMAGTDLFTHIKYMLYSTIPSLLICLVIYGVIGMKYSG
                     QALDIKQIELIRSTLDSTFNTLSPVLLLAPAIVIGLVVFKVPAIPGLIVGAVLGVLFA
                     VVFQGESMNTILDAAQNGYVSSTQIQEVDALLSKGGIMNMMSTVSLTICALSLGGILE
                     KTGMLEVVASSLLRLAKGVFGTVLCTMVTCTITNIIAGEQYLSIVIPGRMYNKEYKKR
                     GIHPKMLSRALEDSGTLTSPLVPWNTCGAYITATLGVSALTYGPYALLNIINPIVSLV
                     LIACKFKIARIEDEPETCLNFDV"
     gene            11648..12112
                     /locus_tag="PC512_003077"
     CDS             11648..12112
                     /locus_tag="PC512_003077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HDF2442807.1"
                     /translation="MTRISNITIAEQSEYCFLAIRKTIDFMVEFSEFSKQSFEKISKY
                     LEERGILSSGAPIVCFHNMDLVKLDVEVGFPVATYIDGKNEILQKIVPAQKIITAIDL
                     GLYELQDPTLEDLFSWANSNGYKLHGDIYYQYLNDINRPASEYLTKMMLPII"
     gene            12346..12708
                     /locus_tag="PC512_003078"
     CDS             12346..12708
                     /locus_tag="PC512_003078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDF2442808.1"
                     /translation="MKIYDILTRFYIQDIEKAIPFYENLLKEKCSLRFSYKEVGLELA
                     QIGNVLLLSGSDDALKPFIETKSTFMVDSVDEWRSYLLDNGAVVVRDKKKVPTGYNMT
                     LRHPDGTIIEYVQHTKQD"
     gene            13292..14128
                     /locus_tag="PC512_003079"
     CDS             13292..14128
                     /locus_tag="PC512_003079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2442809.1"
                     /translation="MSYKVINVITAIDYIEEHLSEKLDLDIVANAVHYSKYHLHRTFT
                     TSVGLTMHDYIKRRKLTEAAKLLVFSKKPIIEIALIAGYESQQAFTSIFKAMYKKSPN
                     KYRKEQEFYPLQLRFVLKKDNLFSKNVLELEKEIKLASMSDIPLWMNLVRLVIDGFPN
                     LQEEEYIYQLEQYILEERALILKLNNVAIANMVFNRETRSIDFFGIHPQYRNSDIAQV
                     FLKKVIEDFLIDTDISITTFREGDKADTGHRDMIKKLGFAEAELLVEFGYPTQKFILP
                     LS"
     gene            14212..16326
                     /locus_tag="PC512_003080"
     CDS             14212..16326
                     /locus_tag="PC512_003080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding domain-containing protein"
                     /protein_id="HDF2442810.1"
                     /translation="MSENKQVVNCDIIASNSKHNMCEYDAELLTFFPDEIAHLIEINN
                     KLDNAFKKAENLVDKLDKDYMDAKMYMVKNRGEIDPHEMFQNEQGLKQIDNYGAFMVK
                     VRDKINKIKDSPYFARIDFRLKDMDDESKYYIGRFAFDYEDELIILDWRSPIASMFYD
                     YEIGKAGYDAPIGWVDGEITRKRQFKIKNGKLEYALESSINIQDDILQKELSHTSDEK
                     MKSIISTIQKEQNQIIRNDKADTLIIQGVAGSGKTSIALHRIAFLLYRFKDKISANNV
                     IILSPNKVFGDYISNVLPELGEEPLCELSFENIAEVQLDRVINFESEKDPLEINDAKW
                     SERVRFKSTLDFVKLIDDYIKQMPNKIFIPKDYTFGSFTAKSDWIQSRFEAYNRYPVK
                     KRLEKVAEDIHYKFESDNIMEEDLPKVKSILKSLNGMLTIKNTLTLYKDFFKQMNISN
                     MFVMAEKKTLEWSDVYPFIYIHAAYEGIQEDKIIRHIVIDEMQDYTPIQYAVINLLFK
                     CKKTILGDFGQLVNPNHTHTLDDMKQLYNDGELVMLNKSYRSTFEIINFAKKIQDISS
                     LEPIERHGEEPALLKCNNEQDEINKIKIEIEEFKKSDNATLGIILKTDNDAKAVYDAL
                     REEYSVHLISSESSSFTKGVSITSIKMSKGLEFDEVIVPSVNNKTYYSDYDRSLLYIA
                     CTRAMHKLKLTYTCELTQLIDM"
BASE COUNT         6488 a         1815 c         3093 g         5015 t
ORIGIN      
        1 ataaatatat gataagataa atacaatagc aacattttat taattttttg ggtttttata
       61 tatttaggta ctggggtgat atagttgaac caagagatat tttttaaaat aatgaatgaa
      121 atattggaaa atattgatga aggggtacat tttgttaata aagacgggaa aactataatc
      181 tacaataatt ctgtacaaaa aatggaaaaa atgaacagac acgatatttt aaccaattca
      241 ttttttgata tagtcaacaa aatgaaaata aacaggagta cactattaga agttttggaa
      301 aaaagggaag ttatcaaaga caatattcaa aaatatctgg ataaaaatgg aaaagagata
      361 acagcaatta atactacaat accaattgat attaaaggcg agtttgtagg ggcacttgaa
      421 atatcaaaga atatgacaac gatagaaaat ttactaaata gaaattataa aaaaaattta
      481 gtcaataaag ttagtattag acaaaaaaag ggttatgaat ttgatgatat tttaggggaa
      541 agtaatttga ttaaagaagc aatagctaaa tctaagaaag cttgcaagtc tgatgcttca
      601 gtatttatat acggtgaaac tggaacgggt aaagagttat ttagccagtc cattcactat
      661 ggaagtaata ggagaaacta tccatttata gcacaaaatt gtgcagcttt gccggaatca
      721 ctattcgaag gtattctttt tggaactagc aagggaggat ttacaggagc aatagatagg
      781 ccaggcttat ttgaacaagc taacaaaggg acattgttat tggatgagat aaattccatg
      841 cctattatgt tacaggctaa actattaagg gttttacaag aaggttatgt aagaagggtt
      901 ggaggaacta aggatatacc tatagatgta agaattattg caacgacaaa tgaaagtcca
      961 aaggtaattt taaacgagca taaaatgcga aaagatttat attataggct taacataatt
     1021 catataaaaa ttcctcctct tagagataga aaagaggaca tacctctatt gtgcaaaaaa
     1081 tttatttcaa agtataataa aaagttaaat aaaaaagtgg taggaatttc agatgaagct
     1141 attaaaattt taaaaaatta cgattggcaa ggtaacataa gagagctaga aaacataatt
     1201 tattgtacta tgagtatgat ggaagatgag gtacaaatag aaacaagtat gattaatcta
     1261 aacgactatt acactcttaa agagaataaa gagagtaaca attattcttt aaacgatttg
     1321 gaggacaaaa cacttagtaa gattatcagt gagatagaag aaaagtatat atatgaatca
     1381 ttagaaaagg catcttacaa tataactaaa gctgcatcaa ttttaggtat gaataggcaa
     1441 aatttacagt ataaaataaa aaaatataat atcaaaatat tataaataag caagataaaa
     1501 aaacaaaatc aaagtaaaat aaaaaagcaa aatagaggag caaaattatt ataaaagagc
     1561 aaaatatttt gctctttttt ttatttctca taagaaatat tattttttat ttatgaaaat
     1621 acataataaa ataattatag tttcaacgtt ccaataaata tttactttaa ttttaaagtt
     1681 ggcacgattt atgctttaac taattattga gaatatataa atttttagga gggtgtatat
     1741 atgagaaaag taagagtagg aatatgggga tttggagcta tgggaatagg tatggctaat
     1801 atgattctaa agaaagaagg tatagaaata gtatctgttt gtagtagaag tacttcaggg
     1861 aaaagtatgt atgatgtttt aggaattgaa agaggagaaa gaccagaagt tattatcaat
     1921 aaaaattatg aagaagtttt tagagaaaaa agtgtagatg ttgttttgtt agcaactgat
     1981 tcatttacta aaaaggcttt tgataaaata aatttcttat taaatagaaa aataaatgtt
     2041 atatcaacag cagaacaaat ggcatatcca caagctgatg atgcagattt agctaaaaaa
     2101 atggatgaag ttgcaaagga aaatggagta agtatacttg gaacaggaat aaatccagga
     2161 tttgtattag atttactagt attggcactt tcaggtactt gtgaagaagt tactagtata
     2221 aaagctaaga gagtaaatga tttatctcca tttggaaagt ctgttatggt ggaacaaggt
     2281 gttggagtaa caagggaaga atttataaaa ggtgtagaag ataagactat agcaggtcat
     2341 gtaggttttg tagaatcaat aaatatgata gctgatggat taggttggaa attagataag
     2401 atagaacaaa caaaagagcc aataatgact acagtagata gaaaatctaa gtacggagag
     2461 gcattggctg gaaatgttgc tggttgtaga caatgtggat atggatatgt aaatggagaa
     2521 gttttaattg aaatggagca tccacaacag ataataccag aagcagaagg tattaaaaca
     2581 ggagactatg tatcaataaa aggtatacca aacattgatt tacaaataaa tcctgaaata
     2641 cctggaggag taggtactta tgcaatgata gtaaactcta ttccattaat aataaatgct
     2701 agaccaggtc ttaaaactat gttggatata ccagtaccta gagcaataat gggagatata
     2761 agaaatcaga tagaagttga attggaagaa gaatcaaagg ctaattagta agatagcaac
     2821 tagctaatta gtaagataac agttagctaa ttggtaaaat aatgtttaat ttaaaataac
     2881 agtaaattaa ttagtaaggc aatagtcaat taataagggg atgaaaaaat ggatgctaaa
     2941 attaatgatt gggttattat acacaatata gtattgactc cagaagaaag agctccacaa
     3001 gttccagagg atactaagaa agtatcctta gaaatgtggg ttaaaggttt tatacaaagt
     3061 gatgcttcta taggcgactt agtagaagtt aaaacaatta caggcagact tgtaaaaggt
     3121 aatttactta aaataaatcc atattatact catgattatg gtaaatgtat accagagtta
     3181 ctccaaatag gaatccaagc taaagaaata ttatttggag gtgtatataa tgaataattc
     3241 aacatcaatg aaagatatga gttatcaagc tgttatggga agaaataacg aaataatgaa
     3301 aaatgcaatc ggattggatt attcttcttt tgaacaagag ggaatagggt ttgattatga
     3361 gaaaatgatg agtgaaacag gatatacatt acaagatatt gaagcaattc aatcacagta
     3421 tgctgttgga aatactcctt taatagagct taaaaatttg actaaattag ctagaaaatg
     3481 tgctaaagaa ggtaaaggag ctagaatatt tgtaaaagat gaagcaatga atgcatctgg
     3541 tagttttaaa gcaagaagag cagctactgc agtatatcat gccaaacaaa tgggatataa
     3601 aggtgtaata gcagctacca gtggtaacta tggtgcagct gtagcatcac aagcggcaat
     3661 gcagggatta aaatgtataa tagttcaaga atgttatgat tctaatggtg taggtcaacc
     3721 tgaaatcata gaaaaagcgc gaaaatgtga ggcatatgga gcagaagttg ttcagttaac
     3781 tgttggacca gagttatttt atacgttctt agttttatta gaagaaacag gctattttaa
     3841 cgcatcatta tattcaccat ttggaattgc aggtgtagaa actttaggtt atgagttagc
     3901 tatccaattt agagaaaagt ataaaaaaga ccctgatata gttgtttgta caaatgcagg
     3961 tggtggtaat cttactggaa ctgcaagagg attgataaaa gctggttcta ttaatactaa
     4021 agtagtagga gcaagtgtag atttaaaagg attacacatg gctagtgata atcaatttaa
     4081 taaaaaatca tttacaacag gacatacagg ttttgggata ccatactgta catggcctga
     4141 taggtcagat gtacctaggt ctgcagctag accacttaga tatatggata gatatgtatt
     4201 agtaaaacaa ggagaagttt tttatacaac tgaattattg gcacagctag aaggtataga
     4261 aagaggtcca gcaggaaata catctttagc agcagcattc tctttagctc aagagctaga
     4321 tgaggataaa gctatagtgg tacaagaaac agaatatacg ggtgcaggta aacatatatg
     4381 tccacaactt acctttgcaa gagaaaatgg aatagatata aaatttggaa atccaagaga
     4441 agaaattgca ggagtaaact taatattacc agaaagacca gaattattga aatgtgttga
     4501 tattgatatg aataaaataa gaaagtcatt tataaaaaat tgtatatcta ataatcacat
     4561 tgataatatt gataagctaa gtaatcgaga tatagaattt ttaatggaag aagtaaaaag
     4621 ttcaagagat tttgttgttg atgtattaaa taatttatag taattattgt tttttaattt
     4681 aatataaaat aaaaattcag aaaattcgat taaatcaata cgaatggagg aatgttcatg
     4741 aaaaaaagag aggatgattt tgaagttaga agaaaacatc ttcaagaact gagtgatgat
     4801 gagttaaaag aaaggttttg gagtttagct acccagatag tagaaccaat gatagaactt
     4861 ggtaaaaaga atacaacacc atcaatagaa aggtctgtct tgttgagaat gggattttct
     4921 tctcttgaag taaaacctat tttagaaggg gttatggaaa gaggtcttat aggtaaagga
     4981 gcagggcatg tagtttataa attggctaaa tctaaaaata taacggttag agaagcaggt
     5041 ttgttattag ttaagggtga atattgggat gaagttacat gtttatttag agaaggggta
     5101 gaatcatgtt aaaggaaaat aaaaaattgg atatagacta tatattaaaa gatttggata
     5161 aatataaacc aaaacgaaga ggttgggttt ggagagaaca cttggaaaat cttgaaatgg
     5221 gaccttttaa atataaagac tgtacaaaac ctttaaagaa gagtgtaggg ctaccatcat
     5281 ctaagtattt caataatata gaccctcaac caagtccagt tattactact gaaatagctt
     5341 ctggtagatt tgaggatgat ataagaagaa tgagaatggc agctcatcat ggagctgacc
     5401 atctaatggt tatcagaact gctggacaat cacattttga tgggcttata gaaggaaccc
     5461 cacaaggtat aggtggagtt ccaataacaa gaaaacaagt aagagctcaa aggaaggctc
     5521 ttgattttat agaagaagaa gttggtagac ctattaatta tcattcatat gtaagtggtg
     5581 ttgctggtcc tgaagtagca gtaatgtttg ctgaggaagg agttaatgga gcacatcaag
     5641 acccacaata taatgttctg tataggaata taaacatggt aaggtctttt gtagatgctt
     5701 gtgaggcaaa gaaaataatg gcttttgcca atatagctca aattgatgga gcacataatg
     5761 ctaatgctac tgctagagaa gcatggaagg taatgcctga acttatggtt caacacgctt
     5821 taaactctat attctcagaa aaaataggta tagataaaag taatatatgc ttatcaacag
     5881 ttccaccaac agcacctcca gcaccatgtt taaaaataga cttaccttac gctgttgcac
     5941 ttagagagtt atttagtgat tataagatga gagctcaaat gaatactaaa tatatggaat
     6001 catcaactag agaagcaaca gttactcatg tattaaactt attaacatca gtattaacta
     6061 gagctgacat acaatcaact ataacacctg atgaaggtag aaatgtacct tggcatatat
     6121 acaatataga agcatgtgat acagcaaagc aagctttagt tggtatggat gggcttatgg
     6181 atatgataga acttaaagat gtcggtgaat taagagacaa agcaagagaa cttaaagaaa
     6241 gagctgtatt atatatggaa gaaatatctg aagttggtgg atattttgaa tctgtggaac
     6301 aaggattttt tgttgattct ggaaattatc cagaaagaaa tggtgatgga atatctagaa
     6361 aaataaaagg tggagttggt gaaggtactg tttatgaaag agaagaagat tatttagcac
     6421 ctgtaactgc tcactttgga tacaataatg tagctcaata tgatgaaaat gctatagata
     6481 atccatcaat gttaatagat ggatgtacat ttgaaaatcc agacaaaata atatatattg
     6541 atgagcttga cgattttgat aatgtagaaa atagactaaa agaatcatat gagtacagaa
     6601 atggaactaa aattaagcct gaaatggaat ggtgtgcaga tggaattata atgataacaa
     6661 tgatgcttcc tactgataaa agaacagcag agtttgcagc tttggaattt gtcaaaaaaa
     6721 tgaacttaca agaaattgag gtcataagta gagaagttat gcatgaatct gaagggacta
     6781 gaatagaagt gaaaggaaga gttccgtttg atatagattt aaacaattta gtaataccag
     6841 aagaacctaa ggtactaact gatgaagaaa taagagcaga tatagaagaa aaacctatga
     6901 aaatagtttc agctacggtt ggagaagatg aacattcagt tggtttaaga gaaataatag
     6961 atataaaaca tggaggtatt gaaaaatatg gcatagaatg ccactatcta gggacttctg
     7021 tacctgtaga aaaattggta gatgcagcga ttgaactgaa tgcagatgca atacttgcat
     7081 ctacaataat aagtcatgat gatattcact ataaaaacat gaaaaaatta cacgattatt
     7141 gtgtagaaaa aggtataaga gataaagtaa tgattgcgtg tggaggaaca caagtaacac
     7201 ctgaaatagc tgttgaacaa ggcatagatg ctggatttgg aagaaacagt aaaggcatac
     7261 atgtagccac tttcttagtt gaaaaaagaa gagaaatgag taataaataa tggaaaatag
     7321 caaggtttct ttaaaaatag atgtgttggt agctgaaatt ggaagtacta ctacagtggt
     7381 aaacgctttc cacgatatta atactaacaa tcctatattt ttgggtcaag gtcaagctcc
     7441 aacaacagtg tttgaaggtg gcgatgtaag aaatggctta tcaggtgcta ttaaagattt
     7501 agctaataaa ttatctgtag atgatataga gtataatgat atgtttgcaa cttctagtgc
     7561 agctggtgga ttaaaaatga ctgttcatgg attagtctat gatatgacag taaaagcagc
     7621 taaagaagca gctttagggg ctggagctgt tattcgtcaa ataacatcag gtagaattaa
     7681 aagaactgat ttaaataaaa taaaagaaat aaacccaaac ataattttaa tagctggtgg
     7741 agtcgattat ggagaaagag atacagctat ttataatgca gaaatgatag cttctatgaa
     7801 tctaggcata ccagttatat atgctggtaa tgttgaaaat caagaggaaa taaggttaat
     7861 atttgaagat actaattata agctttatat aactgaaaat gtatacccta aaatagattt
     7921 attgaatata gaacctacaa gaagaatcat tcaaagtgta tttgaagaac acataactac
     7981 agcaccagga atgaaataca ttaaagaaat ggttaatgaa aatattactc caaccccagg
     8041 agctgtaatg gaagcttcta aacttttata taaaaatatt ggagatttat taactctgga
     8101 tgtaggtgga gcaactactg atgtacattc tgttacagat ggaagtgact atattaataa
     8161 aattttggtt aatcctgaac ctactgcaaa gagaagtgtt gagggggatt taggtgtata
     8221 tgtaaatatg aagaatatag tagaagttat aggtaaagaa aacttacaaa gtgaactatc
     8281 tatagatatt gatgcagtaa tagagaatta tcctccaata ccaaaatcaa aagaagaaat
     8341 attatttgtt gaaagattga caaaagaagc tgttgttaaa gctatgctaa gacattcagg
     8401 aaaaataaga aatatctatg gaacaactgg aaaagtcaaa attgcagaag ggaaagattt
     8461 aacagaagta agatatatag ttggtacagg gggagcactt actaggctcc ctagtagaat
     8521 tgaaatatta gataatatgc tcaaatacaa taaaaataat gaattactat ttccaaagga
     8581 aaaaacaaag atattaatag ataatgacta tattatggca tctatgggtg ttttatctaa
     8641 aaaatatgaa gaagcatctc ttaagctcct gttaaaaagt ttgaattttg aggaggaaag
     8701 attatgtatc ctaggttaga aatagatata gaaaagttaa agcataatgc aaaattaatt
     8761 tcgcagatgt gtcatgaaag aaatattaag atatcttttg ttactaaatc attttgtgca
     8821 caaaaagaaa tagtagaaga aatatgtagt gaaggaatag accatatagc agattcaaga
     8881 atacaaaact taaaaaattt acaagatata aatctaccta agatattgat tagaatccca
     8941 atgttaagtg aattagaaga agttatcaat tattgcgata ttagttttaa ctcagaatta
     9001 ggaacaataa agaaattaaa tgaattatgt gaaagtaaaa atattattca taagatagtt
     9061 cttatgtttg acttaggcga tttacgagaa ggatactttt atgaagaaga cttttttaat
     9121 aatgtaagag agatagtaag attaaaaaat attgaaataa ttggtatagc tacaaactta
     9181 acctgttatg gagctattat accatctagg gaaaatatag gcagactggt aagtatagca
     9241 aaaagaatgg aagaaaaatt tggaataaat ctagaaatag tatctggagg taattcaagt
     9301 tctattcatc tgttgataaa taataatatg ccagaaggta ttactaattt gagaataggc
     9361 gagtccattc tacttggtag agaaacggca tacggtgaaa atataaatgg aacatatcaa
     9421 gatgcattta aattaatatg ccaagtagtt gaatgtaaag aaaaaccatc agttcctatt
     9481 ggagaaatag gagttgatgc ctttagaaat aaacctgttt atgaagataa gggaatctta
     9541 aaaagggcaa tcatagctat aggtaaacaa gatataaata ttgactcttt aattccaata
     9601 gacactgata taaaaatatt aggggcaagt tcagaccaca tgatactaga tgtaagtaac
     9661 acaaaatatg attataaatt aggtgacaat ttagaatttt tattaactta tgggggtatc
     9721 atgtcatcta gtacgagcaa atatgtttca aaaaaaatta tagtgtagtg tttaaataat
     9781 taggaggaaa ctattttatg aaagagcgag aatgtagaaa agcaagtctg tttgatgcaa
     9841 tgataccaat tacttgtttg atattatttt taagtctagg agtattagtg tatggttcat
     9901 cacctcatgt accactaata ggagcagcag cagtagcagg acttgtggct gtatatagac
     9961 ttggatttaa atggaaagag ttagaattaa gtatgtttaa tagtataaag atggcaatgc
    10021 aagcaatctt aatcataatt ataataggcg tacttatagg aacttggata gtaagtggag
    10081 tagttccatg tatgatttac tggggactaa aaattttatc accaaatatt tttttagtag
    10141 catcaacatt agtctgtgca atagtatctc ttgcgacagg ttcatcttgg agcacaatgg
    10201 gtacagtagg agtagctctt ttaggaattg gtcaaagttt aggtatgcca attggattaa
    10261 tcgtaggttc tataatatct ggagcttact ttggagataa actatcacct ttatctgaaa
    10321 cgactaactt agctccagca atggcaggaa cagatttgtt tacacatata aaatatatgc
    10381 tatattcgac tataccatca ttattaattt gtttagtaat ttatggtgta attggaatga
    10441 agtattcagg tcaagcacta gatataaaac aaatagaatt aattaggtct acattagatt
    10501 ctacatttaa tactttatca ccagtattat tattagctcc agcaatagta attggattgg
    10561 ttgtatttaa agttcctgct ataccagggc ttatagtagg tgctgtattg ggagtattgt
    10621 ttgcagtagt ttttcaagga gaatctatga atacgatatt agatgcagca caaaatggat
    10681 atgtttcgtc aacacaaata caggaggtag atgctttatt atctaaaggt gggattatga
    10741 atatgatgtc cactgtatcc ttaacaatat gcgctttatc tcttggaggt attttagaaa
    10801 aaacaggtat gcttgaagta gtagcatctt ctttactaag attagcaaag ggtgtatttg
    10861 gaacagtatt atgtactatg gtaacttgta caattaccaa tataatagca ggtgaacaat
    10921 atctatctat agttatacca ggaagaatgt ataataagga atataaaaag agaggtatac
    10981 atcctaagat gttgtcgaga gctttagaag atagtggaac tttaacttct ccattagtac
    11041 catggaatac atgcggggcg tatataacag caacattagg tgtatctgca ctaacatatg
    11101 gtccatacgc tttattaaat attataaatc caatagtatc tttagtatta attgcatgta
    11161 agtttaaaat agcaagaata gaagatgaac ctgaaacttg tttaaatttt gatgtttgat
    11221 aatagataac ttatgtaaga acgtaggaac taggggggta gcctgtgggg aattagtaag
    11281 acatatttta gtgtgcgaaa ttctataaat cagtaatctt gtgactttag ccatgggagg
    11341 ttcagattag taaatttata gttttatatt agtctatatt ttgatatttt aattgtttgt
    11401 ataaattttt tatagaaaaa gatttctttt agacttgcct aaaaattagg caagtctttt
    11461 aagtatgttc tgattataag agcactgtgt gacaagaatg atgagattat ttttgctata
    11521 ctttcgatat aagaaatgga aggaggttat gttttatatt catatgaaat aattagttac
    11581 acagtgaatt ttcgtataat ttggtataaa aagattagaa atgaaaataa agtaatggag
    11641 gaataaaatg actagaatat ccaatataac aatagctgaa caatctgagt actgtttttt
    11701 ggcaatacga aaaacaattg actttatggt agaattttca gagttttcaa aacaaagttt
    11761 tgaaaaaatt tctaaatatc tggaggagag aggaatttta tcttcaggag caccgattgt
    11821 atgttttcat aacatggatt tagtaaaatt ggatgttgaa gtagggtttc ctgtagccac
    11881 ttatatagat gggaaaaatg agattctaca aaagattgtt cctgcacaga aaataataac
    11941 tgcaattgat ttaggacttt atgaattaca agaccctact ttagaagact tattttcatg
    12001 ggcaaatagc aatggatata aacttcatgg cgatatatat taccagtatt taaatgatat
    12061 caatcgtcca gctagtgaat atcttacgaa aatgatgtta cccattatat agaaagttaa
    12121 agattatcgt ttgttagttg ataattagaa gaacatttac tgctactaca taaattttat
    12181 cctaaataat atcaaggtga tttaatttat gtattctaat gtaaccccaa tatattgtta
    12241 aggtctactt aagatgctca aaaggctatg cttaatttat tgttatataa tttgtagagt
    12301 ggtataattt agaggtaata ttatatagat atataggggg aaaatatgaa aatatatgat
    12361 atattaacac gtttttatat tcaagatata gaaaaagcca taccttttta tgagaatctt
    12421 ttaaaagaaa aatgttcttt gcgtttttcc tataaagaag ttgggttgga attagcgcaa
    12481 ataggaaatg ttttactatt atctggttct gatgatgctc ttaaaccatt tatagaaaca
    12541 aaatctactt ttatggttga ttctgttgat gaatggagaa gttatctatt ggataatgga
    12601 gcagttgtag taagagataa gaaaaaagtt cctacaggat ataatatgac attgagacat
    12661 ccagatggta caattataga atatgttcaa catacaaagc aggattagtt aaaaacagat
    12721 tttactactg agcaactaat tagaatctat tcttagacgt acaatttatt atttttggta
    12781 ttaatagatt ataagtcaaa ttataatatt tcaaaataga atagaaattt atttacataa
    12841 aagagagtgt ttaaaaatga actttttagt tcatgaagca ctcttttttg tatgaaatca
    12901 aatacatcaa tatataaaat aaactgatga agagcttaaa ttaaaataaa aagattcata
    12961 acaggacccc attaaacttt aagatagggt aagtttgtaa tcatattaaa taattgtaaa
    13021 aagctgtttt tagtcgtata atataaatat ttatcattta attaaggaat ctaataagaa
    13081 gaaaataata aataactttt tagatttact aaatgaaaag ttattgaaaa ttaaaggatt
    13141 agagtcttta atcagaaagt aaaaagtaat atattaaatt tatgaattga aaacttaaac
    13201 aacaaatttg tttataaaat agcaagattc attaaatata actaagtaat aattgatata
    13261 atgttgcatg gataaaagga gggaagctgc aatgtcttac aaagtaatta atgtcataac
    13321 tgctattgac tatatagagg agcatttatc agaaaagctg gatttagata tagttgctaa
    13381 tgctgttcat tactcaaaat atcacctgca tagaactttc acaacttctg ttggcctaac
    13441 aatgcatgat tacataaagc ggagaaagtt gacagaagca gcaaaattat tggtattttc
    13501 aaagaaacca attattgaaa ttgcattgat agctggatat gaaagtcaac aggcattcac
    13561 ttctatattt aaagctatgt ataaaaaatc tccaaataaa tataggaaag aacaagaatt
    13621 ttatcctttg cagctaagat ttgttttgaa aaaagataac ctattttcaa agaatgtact
    13681 agagttggaa aaagaaatta aacttgcaag tatgtctgac ataccattat ggatgaattt
    13741 agtgagatta gtcatagatg gatttcccaa tttgcaagag gaagaatata tatatcaatt
    13801 agaacagtat attttagaag aaagagcttt aatattaaaa cttaataatg tcgctattgc
    13861 aaatatggtg tttaatagag aaactagaag tattgatttt tttggaatac atccacagta
    13921 tcgtaattca gacattgcac aagtgttttt gaagaaagtt attgaagatt tcttgataga
    13981 tacagatatt tcaattacta cctttcgaga gggtgacaaa gctgatacag gacatagaga
    14041 tatgataaag aagttgggct ttgcagaagc agaattgctt gtggaatttg gatatcctac
    14101 tcaaaaattt attcttcctt taagttaaat agcaagaatg attaaaaact ccaaaacaca
    14161 attaagtata atgattcagt gtaagtactt aattaacaaa ggaggattta aatgtctgaa
    14221 aataaacaag tagtaaattg cgatattatt gcatctaatt ctaaacataa tatgtgtgaa
    14281 tatgatgcag agttattaac tttttttcca gatgagattg cacatctaat agagataaat
    14341 aacaagctag acaatgcttt taagaaagct gaaaatcttg ttgacaagct tgataaggat
    14401 tatatggatg ctaaaatgta tatggtaaaa aatcgtggtg aaatagaccc acatgaaatg
    14461 tttcaaaatg aacaaggact aaaacaaata gataactatg gggcttttat ggtaaaagtt
    14521 cgagataaga ttaataaaat caaagattct ccatactttg ctagaataga ttttaggttg
    14581 aaagatatgg atgatgaatc taagtattat attggtagat ttgcatttga ttatgaagat
    14641 gagcttataa tacttgactg gcgttctcca attgccagta tgttttatga ttatgaaatc
    14701 ggaaaagctg gatatgatgc tccaatagga tgggtggatg gagaaataac aagaaaacga
    14761 caatttaaaa ttaaaaatgg aaaattagaa tatgcactag aaagttccat taatatacaa
    14821 gatgatattc ttcaaaaaga acttagtcac acttcagatg aaaaaatgaa gtcaatcatt
    14881 tcaacaatac aaaaggaaca aaatcaaatt attagaaatg ataaagctga tacactgatt
    14941 attcaagggg tagctggttc tgggaaaaca tctatagcat tacacagaat tgcttttctt
    15001 ctttatcgat ttaaagataa aatatcagca aataatgtaa ttatcctatc acctaataaa
    15061 gtctttggag actatatttc caatgtcctt cctgagcttg gagaagagcc attatgtgaa
    15121 ttaagttttg aaaatatagc agaggtacaa ttagatagag ttattaattt tgaaagtgag
    15181 aaagacccat tagaaataaa tgatgctaaa tggtctgaaa gagtgcgttt taaatctaca
    15241 cttgattttg taaaacttat tgatgattat ataaaacaaa tgccaaataa gatttttatt
    15301 ccaaaagact acacttttgg aagttttaca gctaaaagtg actggataca gagtagattt
    15361 gaggcatata acagatatcc agttaagaag agattagaga aggtagctga agacattcat
    15421 tataaatttg aatcagataa tattatggaa gaagatttac caaaggtaaa aagtatactt
    15481 aaaagtttga atggaatgtt gacaataaaa aatactctta cactatataa ggatttcttt
    15541 aaacaaatga atatatcaaa catgtttgtg atggcagaaa agaaaacact tgaatggtca
    15601 gatgtatacc catttatata tattcatgct gcatatgaag gtatacaaga agataagatt
    15661 ataaggcata ttgttattga tgaaatgcag gactatacac ctattcaata tgctgtaata
    15721 aacttacttt ttaagtgtaa aaagactatt cttggagatt ttggacaatt ggttaatcct
    15781 aatcatactc atacactaga tgatatgaaa cagctatata atgatgggga attagttatg
    15841 ttgaacaaga gttaccgttc tacttttgag attattaatt tcgccaaaaa gattcaagac
    15901 atatcttcat tagagcctat tgaacgacat ggtgaagaac cagctttatt aaaatgtaat
    15961 aacgagcaag atgaaataaa taagataaaa atagaaattg aagaatttaa aaagagtgat
    16021 aatgcgactc ttggtattat attaaagaca gataatgacg ctaaagctgt atatgatgcg
    16081 ttaagagaag aatatagtgt tcacttaata tcttctgaaa gttctagctt tacaaaagga
    16141 gtatccataa cttctattaa aatgtcaaaa ggtttagagt ttgatgaagt tattgtacct
    16201 tcagtaaata ataaaacata ttatagtgat tatgaccgca gtttgttata tattgcctgt
    16261 acacgagcta tgcataaact taagttgaca tatacttgtg aattgactca acttatagat
    16321 atgtagatta tatacttatt atgtaagtgt ttacttatat aaatataacc tgtcaataaa
    16381 attcattaat aaatcaataa aaacaatatt t
//
LOCUS       DAMJVG010000087        16151 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.089, whole genome shotgun sequence.
ACCESSION   DAMJVG010000087 DAMJVG010000000
VERSION     DAMJVG010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16151)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16151)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16151
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.089"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            157..1605
                     /locus_tag="PC512_003081"
     CDS             157..1605
                     /locus_tag="PC512_003081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HDF2442811.1"
                     /translation="MKLGKDFLWGGAISANQSEGFYLDGGKGLSQFDKLPLNDKRLKD
                     VCLDEDNILNENNQYYPSHIGIKFCENYKEDIAMLAEIGFKCFRFSISWSRIFPTGEE
                     SEPNEKGLQLYDNIIKELKKYNIEPLITISHFDIPYSLVEKYSGWADRRVVNLYVKYA
                     EILMKRYKDDVKYWIPFNEMNMIMHIPYIGAGLTFIADENQLQKKYQAAHHQLLANAK
                     TIEIGRYINKEFKFGCMLAAGKTYPYTCKPEDVFATLEHERHNLFFSDVQVRGVYPSF
                     MNYYLKSNQIKLIIKEEDLSTLKDNTVDFVSFSYYSSACSSARAEGLEKSKANGPETI
                     KNPYLPKSNSVWQNDPVGLRITMNQLYERYQLPLFIVENGLGTQDIVNEDGKIIDDYR
                     IDYMKEHIKNMIIGVNEDGIELIGYLMWGCIDVTSVSEGKMTKRYGIIHVDSDDYGRG
                     SFKRTKKQSAFWYKKVIETDGEILFNDMETHA"
     gene            1631..4021
                     /locus_tag="PC512_003082"
     CDS             1631..4021
                     /locus_tag="PC512_003082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HDF2442812.1"
                     /translation="MSLIFTTKDQLIEQGFSKDTIKSNETLFTLANGHLGVRGNIEES
                     DFNNEYVDNMGTYVNGFYEESPITYGESAYGYAKQNQTICKLPNAHIVNFSIEGDCFD
                     LSKGITSEHSRILDLNEGILKRSFIWENSRGRKVKVSIERLVSQDIEELMMISYTITP
                     LNFNGKIKFKNKMENSMEKFNCEKVEDPRVASINKKQFKINVKKYNNKYFMNLVTERS
                     RLGLWCGFDSYITCGNITNETYNVSDECIEREIEVYAKKDERLNLEIVVGYSRVYSDL
                     NLNEERLKSLECLESLKCLESEAHLKSLELVLREACNIGFDKVKNIQRKKMNEFWTTS
                     DVEIEGDKTLQLGIKTNLFHIYQSVGRDGKTNISAKGLTGDGYEGHYFWDTEMYILPF
                     FIYTQPSIARALLDYRYSILDASRERARELGINKGCLYSWRTINGNECSAYYPAGTAQ
                     FHINADIAYGIRTYFEATNDEEFMMQNGLEILIETARFWVEFGDYIESKNNKFCINGV
                     TGPDEYTAIVNNNYYTNLMAKYNLIYAVQMVDKFKHNLFSNEVFRKVKLQEYEVKNWI
                     NAAQNMYLPYDEEKKISKQDDSFLEKSVWDFKNTPKEKYPLLLHYHPLTIYRYQVNKQ
                     ADTVLSALLFPDEFSLEQKKRDFEYYEKITTHDSSLSRSIFGMMASEIGNHEKAYNYF
                     MDTALMDINNLQKNTSDGIHAANMGGTWMSLVYGFAGMKIKNDKLSFEPRIPKHWKNI
                     KFNILFRDNLVSVNIEEYKSYYKLIKGRNITILHDNKEIKLSKNIIEVNNCFKGSN"
     gene            4023..4694
                     /gene="pgmB"
                     /locus_tag="PC512_003083"
     CDS             4023..4694
                     /gene="pgmB"
                     /locus_tag="PC512_003083"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HDF2442813.1"
                     /translation="MKAVLFDLDGVITDTAKYHFEAWHEIAKSLDIEIDETFNEKLKG
                     ISREESLDKILLSANKVDSYTKEEKLKVCEEKNNIYIKLINSLTYKDILPGINELIKE
                     LKKNNVKLGIASASKNAPRILESLGIKDEFDCIVNPSLLKRGKPYPDIFIEGSKILNL
                     KQYDCVGIEDSYSGIKAINAANMTSIGVGKKEVLGKCDHIVEDTSLLNYNTLLQAWSK
                     KINLD"
     gene            4733..6103
                     /locus_tag="PC512_003084"
     CDS             4733..6103
                     /locus_tag="PC512_003084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDF2442814.1"
                     /translation="MKNKYEEVAQLIIDGLGGKDNIIDLTHCMTRLRFILKDEKKVNA
                     DKLKSIDKVVGVNSTSTQYQVIIGNEVGVVFNAIINKGINTTGDIKSDIKNKNKKNSI
                     LNNIIDTITGCMTPMIPALTASGMIKVILSLCTTFNWLSSNSSTYRVLDIIGDVAFYF
                     MPIILAINAAKKFNVNTSIAVIVVGVFLHPNFSAWVSSGDPISFIGVPIQDVIYAASV
                     IPALLTVWMMSYIEKFIDKLTPSMLKTILNPTLVLLISAPIALIVIGPIGNFLGEGLA
                     SIINLLQGRLGFIMVCLLAAAMPFIVMTGMHHALTPIFISAFATTGQESLILISQVCA
                     NLAQGGATLAVALRSKDSKMKQLASAAWISAIMGITEPALYGVTLKLKKPAMLASIGA
                     GIAGLFAGITHVTLYVPQNSIMAVLGLSGEKGISNIVNGLIVIFIALVAPFIMTYVFG
                     VEKNVK"
     gene            6450..7292
                     /locus_tag="PC512_003085"
     CDS             6450..7292
                     /locus_tag="PC512_003085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF2442815.1"
                     /translation="MIINKILNNNVVITLDDNDEEVIVMGKGIGYQKSKGNLIDKTKV
                     NKVFRISNKEISNKLQELLNNIPIEHMKLSSEIIEYAQIKLNKKLNESIYISLSDHTY
                     SAIQRMKEGINVKNAILWEIKRFYKEEFEIGMKALDIIENKTGIKLPEDEAGFIAFHI
                     VNAQLSEGHTLASDITKLIQEVLSIVRYHFRIEFHEESVFYYRFIMHLKFFAQRLLLD
                     SAHEGETDKELLSIIKSKYNKEFECVVKIKNFIKKQYNYILTDDELIYLTIHLAKVVK
                     DSNM"
     gene            7437..9365
                     /locus_tag="PC512_003086"
     CDS             7437..9365
                     /locus_tag="PC512_003086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2442816.1"
                     /translation="MGKYKQLAQEIVNNVGGKENISGLVHCITRLRFTLKDESIANDN
                     VLKNMEGIVTVMKSGGQYQVVIGNHVEAVYKDVVEIIGLDDSSTSSETKKSGNILDKG
                     IDIISGIFQPVLGIMAACGMLKGFNALFVAMGLYSDVSGGYMVINAAGDALFTFLPLF
                     LGYTSAKKFGLKPMLGLALGAAVCYPAIQGSSISAGADVMYTLFKGTMFASPVYIDFF
                     GLPIVSIDYTGTVVPIIFIVYFASRCEKLFNKCVPNLVKFFFVPMLTLLITVPVALIV
                     IGPIATFGSTLISQIVISIRDFSPLLAGAIVGFTWQILVIFGMHWGFIPVYINNVMTL
                     GYDNVMMPFFACTFASSAVVLAIFFKTKDKKLKEMAIPNFISGIFGVTEPAIYGILLP
                     LKKPFIISCIASGIGGAFYGFFNLRKFITGGMGIFELPAMIEPDGGMGNLIVALSGIA
                     ISMVVAFVLTMILYKDEKVEESKKVRNKGKEEIKEVKSTKLEREIVTSPIKGEVLKLS
                     DIEDAAFASGVLGQGVAIIPSDGKVVAPVDGVVTTLFPSLHAIGILSDTGVEVLIHIG
                     LNTIQLEGRGFEACIKQGDRITKGQTILNFDVYAIKELGYSTVTPIVITNSSQFLDVV
                     ETESKNIELEDNLITVLF"
     gene            9426..10853
                     /gene="ascB"
                     /locus_tag="PC512_003087"
     CDS             9426..10853
                     /gene="ascB"
                     /locus_tag="PC512_003087"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HDF2442817.1"
                     /translation="MSFKNDFLWGGATAANQCEGGYNEDERGLANVDVCPTGKDRTAV
                     ITGKLKMFDFDDEHYYPAKTGIDMYHNYKEDIKLFAEMGFKVYRMSIAWSRIFPKGDE
                     ETPNEKGLQFYENIFKECKKYKIEPLVTITHFDCPMHLVKKYGAWRNRKMIGFYEKLC
                     NVIFRRYKGLVKYWLTFNEINMILHAPFMGAGICFEEGEDVEKIKYQAAHHELVASAI
                     ATKIAHEVDSNNLIGCMFAAGSVYPYSCNPNDVWEATKLDRENYFFVDVQSKGKYPNY
                     ALKYMEQKGITPEMEPGDIELLNKYTVDFISFSYYNSRCVRTDENADDMAEGNIFTSA
                     KNPYLSYSQWGWPIDPLGLRITLNHVYDRYEKPLFIVENGLGAKDIADENGYVEDDYR
                     IDYLREHIKAMHDAVSIDGVDLLGYTTWAPIDLVSAGTGEMEKRYGFIYVDRDNSGNG
                     SLRRMKKKSFEWYKKVIASNGEDLY"
     gene            11300..12076
                     /locus_tag="PC512_003088"
     CDS             11300..12076
                     /locus_tag="PC512_003088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF2442818.1"
                     /translation="MKYQHIIEVDKELCIGCGLCKNDCPVNNIIIENKKSVIKKQDCL
                     MCGHCAAICPTKAITLTGFDEPPIELTNKPKLDSDELLMAIKSRRSIRKFKDKEVSSE
                     IIKQIIEAGRYTPSAKNSQDVSYIVLDNKKSIYENEAVKFFRKIKPIANIAIKYSKEV
                     EIDDNFFFKHAPIAIMIITKDKISGSLAASNMALMAESYGLGVLFSGYFSDVANNSPK
                     LKKLLGLKRSNHVLTTLVIGYPDVKYRRTAQKEVATVRYL"
     gene            12092..12457
                     /locus_tag="PC512_003089"
     CDS             12092..12457
                     /locus_tag="PC512_003089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDF2442819.1"
                     /translation="MEKECQQRMQEITSKFKECRKAISAMGDETRQLILIALLESDFN
                     GIRVGEITKKTHLSRPAVSHHLKILKEAEIVNLRREGTKNYYYLDSKKSQWKSLTELI
                     NLIFVGIQHISENDIRKGD"
     gene            complement(12623..13372)
                     /locus_tag="PC512_003090"
     CDS             complement(12623..13372)
                     /locus_tag="PC512_003090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440038.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HDF2442820.1"
                     /translation="MILYFSGTGNSRYVARKIAQELNDELISLNQLIKEEKTDELISA
                     DKPFIFVCPTYAWRLPIVVTDFIKETKFLGSNRVYFVMTCGGDTAKSINYIQKLCKYK
                     EWQLKGMAEIKMPENYIALFSTTDKETSKQMIKEADKQIYRIISDIRNENEFETITPS
                     GLGGTIKSGIINTVFYKTIISAKGFHYTDKCIGCGKCVELCPLNNINLKNKKPVWKNN
                     CTHCMACICGCPTEAIEYKNKTQNRERYYLE"
     gene            13830..14255
                     /locus_tag="PC512_003091"
     CDS             13830..14255
                     /locus_tag="PC512_003091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2442821.1"
                     /translation="MINENLKSLRKINQYTQEELAEKLNVSRQSIAKWESGESIPDIC
                     SCIKLAKLYNVKLDDLVNHSEEKTGIIVPPKGKFFFGAVVVGERGQIVIPKEAREVFN
                     INAGDKLLVLGDEERGLGIVHQRDLINFIGHVGVVRKEE"
     gene            14287..15474
                     /locus_tag="PC512_003092"
     CDS             14287..15474
                     /locus_tag="PC512_003092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HDF2442822.1"
                     /translation="MSKIVFFSIPAYGHTNPTIEVVRELVDRGNEVLYYSFNEFKDKI
                     EGAGAKFICCDKYLPELLPGDEKKIGKDFPGLIEMIVDTTISLDEKVCRELKDFNPDC
                     IVSDSLSFWGKLFAQKLNIPYVCSTTTFAFNKHTAKLMKQNFIEIIRMIFGVRRINKK
                     IKLLQRKGYEVKNFISIVSNDNDTDTIVYTSKEFQPMVETFSSKYSFVGPSVSKLIIE
                     PKERKRKLIYISLGTINNKNVSFYKNCISAFKDSDVDVIMSVGRSTDIKSLGNIPNNF
                     EVKNSVEQIAILQKTDVFVTHSGMNSVNESLYYGVPMVLFPQHSEQRMVAKRVVHLGA
                     GIMLKEDKSESIKKAVFQVINDNEYKENATKLSKSFYNAGGSKKAADVILQIICNSRQ
                     VDI"
     gene            15666..16070
                     /locus_tag="PC512_003093"
     CDS             15666..16070
                     /locus_tag="PC512_003093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3139 domain-containing protein"
                     /protein_id="HDF2442823.1"
                     /translation="MKKYKVIFIVLIIGIISVTGFVVYKNCIKPWKDAETYIDKYMVK
                     QDISKDNIKSITKEKAKKASYEGILYKVYYKDDPRYEYQYFYSDNYYALYVNKVMLQI
                     YDMENNNKLLRSNEELKSVKYPLIYLKYKPDK"
BASE COUNT         6361 a         1693 c         2861 g         5236 t
ORIGIN      
        1 tgaaagtatt gaaaatagac aatattaatt atagtgagta aaaaatataa ttggattttt
       61 aaattgaatt atttaaaagg tatagtatga aaaaaatctt ataactaaat atgagataga
      121 aattataaaa ctttatattg tgaaagaggt agatgcatga aattagggaa agatttttta
      181 tggggagggg caatttcagc caatcaaagt gaaggatttt atttagatgg aggaaaaggt
      241 ttatctcagt ttgataaact cccattaaat gataagagat taaaagatgt atgtttagat
      301 gaggataata ttttaaatga aaataatcaa tactatccaa gtcatatagg gattaaattt
      361 tgtgaaaatt acaaagaaga tatagcaatg ttagcagaaa taggttttaa atgttttaga
      421 ttttctatat cttggtcaag aatattccca acaggagaag aaagtgaacc aaatgaaaag
      481 ggattacaac tttatgataa tataataaaa gaattaaaaa aatataatat agagccatta
      541 ataacgataa gccactttga tataccttat tctctagttg aaaaatattc tgggtgggct
      601 gatagaagag tggttaattt atatgtaaaa tatgctgaaa ttttgatgaa aagatataaa
      661 gatgatgtca aatactggat tccttttaac gaaatgaata tgataatgca tattccatat
      721 ataggtgctg ggttaacttt tatagctgat gaaaatcaac ttcagaaaaa atatcaagca
      781 gcacaccatc aattattagc taatgcaaaa actatagaaa taggaaggta tataaataaa
      841 gaatttaagt ttgggtgtat gttagctgct ggaaaaacat atccatacac atgtaaacca
      901 gaagatgtat ttgcaacttt agagcatgaa aggcataatt tgtttttttc tgatgttcaa
      961 gttaggggtg tgtatccaag ctttatgaat tattatttaa aatcaaatca aataaaatta
     1021 ataataaaag aggaagattt atcaacactt aaggataata ctgtagattt tgtatctttt
     1081 agctattatt ctagtgcttg tagttcagct agagctgaag gtttagaaaa atcaaaggca
     1141 aacggaccag aaaccataaa aaatccatat cttccaaaat caaatagtgt atggcaaaac
     1201 gaccctgtag ggttaagaat aactatgaat cagttatatg aaaggtatca gttaccttta
     1261 tttatagtag aaaatggact gggtactcaa gatattgtaa atgaagatgg aaaaataatt
     1321 gatgattatc gtatagatta catgaaagaa catattaaaa atatgattat tggagtaaat
     1381 gaagatggaa tagagcttat aggatatctt atgtggggat gtatagatgt aaccagtgta
     1441 agtgaaggaa agatgacaaa acgatatggc ataattcatg ttgattctga tgactatgga
     1501 agaggctcat ttaaaagaac taaaaaacaa agtgcttttt ggtataaaaa agtaatagaa
     1561 acagatggag aaattttatt taatgacatg gaaactcatg cataattcat tttaagaaag
     1621 gagtgttatt atgagtttaa tatttactac taaggaccaa cttatagagc aagggtttag
     1681 taaggataca ataaaatcca atgaaacgct gtttacacta gctaatggac atttaggagt
     1741 tagagggaat attgaagagt ctgattttaa taatgagtat gtagataata tgggtacata
     1801 tgtaaatgga ttttatgaag aatctccaat tacatatgga gaaagcgctt atggctatgc
     1861 aaaacaaaat cagactatct gtaagttacc taatgctcat atagtaaatt tctctattga
     1921 aggagattgc tttgatttat caaaaggtat tacaagtgaa cattctagga tactagattt
     1981 aaatgaaggg attcttaaac gttcatttat atgggaaaac tctcgtggta gaaaagttaa
     2041 agtatctata gaaagattag tatcacaaga tatagaagaa ttaatgatga tttcatatac
     2101 aataacacca ttgaatttta atggaaaaat aaaatttaaa aataaaatgg aaaatagtat
     2161 ggagaagttt aattgtgaaa aagtagagga cccaagagtg gcatctataa ataagaagca
     2221 atttaaaatt aatgtaaaaa aatataacaa taagtatttt atgaatttag ttacagaaag
     2281 aagtagatta gggttatggt gtgggtttga ttcatatatt acttgtggaa atattacaaa
     2341 tgagacctat aatgtttcag atgaatgtat tgagcgagaa atagaagtct atgccaaaaa
     2401 agatgaaagg ttaaatttag aaattgttgt aggctatagt agagtatatt ctgatttaaa
     2461 tctaaatgaa gaacgtttaa aatcattaga atgtctggag tcgttaaaat gtttagaatc
     2521 agaagcacat ttaaaatcat tagaattggt tttaagagaa gcatgtaata ttggatttga
     2581 taaagtcaaa aatattcaga gaaagaaaat gaatgagttt tggacaacct ctgatgtaga
     2641 gattgaaggc gataaaactc ttcaactggg gataaaaacc aatttatttc atatttatca
     2701 atcagtagga agagatggaa agactaatat atcagcaaaa ggtcttacag gtgatggcta
     2761 tgaggggcat tatttctggg atacagaaat gtatatatta ccatttttta tatatactca
     2821 accatccatt gccagagctt tattagatta tagatactca atcttagatg catcaagaga
     2881 aagagctaga gaacttggaa taaataaagg ttgcttatat tcatggagaa ctataaatgg
     2941 taatgaatgc agtgcatatt atccagcagg aacagcacag tttcatataa atgcagatat
     3001 agcttatggt attagaacgt attttgaagc aactaatgat gaagaattta tgatgcaaaa
     3061 tggcttagaa attcttatag aaacagcaag attttgggtt gaatttggag attatataga
     3121 atcaaaaaat aataaattct gtataaatgg agtaacagga ccagatgaat atacagcaat
     3181 agtaaacaat aattactaca ctaatttaat ggctaagtat aatttaatat atgcagtaca
     3241 gatggtagat aaatttaagc ataatttatt ttcaaatgaa gtatttagaa aagttaaatt
     3301 acaagaatat gaagtgaaaa actggataaa tgccgctcaa aatatgtatt taccatatga
     3361 tgaagagaag aaaataagca aacaagacga ttcattttta gaaaaatcag tatgggattt
     3421 taaaaataca ccaaaagaaa aatatccatt acttcttcat tatcatccat taacaatata
     3481 tagatatcaa gtaaataaac aagcagatac tgtactttca gcgttgcttt tccctgatga
     3541 gtttagctta gaacaaaaga agagagattt tgaatactat gaaaaaataa ctactcatga
     3601 ttcatctttg tcaaggtcaa tatttggaat gatggcaagt gaaattggaa atcatgaaaa
     3661 agcttataac tattttatgg acacagcatt aatggatatt aataacctac aaaaaaatac
     3721 aagtgatgga atacatgctg ctaatatggg tggaacatgg atgagtttag tatatggatt
     3781 tgcaggaatg aaaataaaaa atgataaatt aagttttgaa ccaaggatac ctaaacactg
     3841 gaaaaatatt aaatttaata tattatttag agataattta gtttctgtaa atatagaaga
     3901 atataaatct tattataagt taatcaaagg tagaaatata accatattac atgataataa
     3961 agaaataaaa ttatcaaaga acataataga agttaataat tgttttaaag ggagtaatta
     4021 atatgaaagc agtcttattt gatcttgatg gagttataac agatactgct aagtatcatt
     4081 ttgaagcttg gcatgagata gcaaaatcgc tagatataga aatagatgaa acttttaatg
     4141 aaaaattaaa aggcataagc agggaagaat cattagataa aatattgtta tctgctaata
     4201 aagtagatag ttatactaaa gaggaaaagt taaaggtgtg tgaagaaaaa aataacattt
     4261 atataaagtt aataaactca ttaacatata aagatatatt accagggata aatgagctta
     4321 taaaagaact taaaaaaaat aatgtgaaat tgggaatagc atctgctagt aagaatgcac
     4381 ctaggatatt agaatctttg ggaataaaag atgaatttga ttgtatagta aatccatctt
     4441 tattaaaaag gggaaaacca tatcctgata tttttattga agggagcaag attctaaatt
     4501 taaaacaata tgattgtgta ggaatagaag attcttattc aggtattaaa gctataaatg
     4561 ctgctaatat gacatcaatt ggtgtgggga aaaaagaagt actaggaaaa tgtgaccata
     4621 ttgtagaaga tactagctta ttaaattaca atacactatt acaagcttgg agtaaaaaga
     4681 ttaatttgga ttaaaattat attaaaaatt attttaaaag agaggataag gtatgaagaa
     4741 taaatatgaa gaagtagctc aattgataat tgatggactt ggaggaaagg ataatataat
     4801 tgacttaact cattgtatga cacgattaag gttcatctta aaagatgaaa agaaagtcaa
     4861 tgcagataaa ttaaaatcta tagataaggt agttggagta aactcaactt caactcaata
     4921 tcaggtcata ataggtaatg aggtaggtgt tgtatttaat gcaataataa ataaggggat
     4981 aaataccaca ggagatatta aaagcgatat aaaaaataaa aataaaaaaa atagtatttt
     5041 aaataatata atagatacaa taactggttg tatgacacct atgataccag cccttacagc
     5101 atctgggatg ataaaagtta tattatctct ttgcaccact tttaattggc tatcatcaaa
     5161 ttcaagtaca tatagagtat tagatataat aggagatgta gcattttact ttatgcctat
     5221 aatacttgca ataaatgcag ctaaaaaatt taatgttaat acatcaatag cagttatagt
     5281 agtaggtgtg tttttacatc caaatttctc tgcatgggta tcaagtgggg accctatatc
     5341 atttatagga gtaccaattc aagatgttat atatgcagca tctgttatcc ctgcactttt
     5401 aacagtatgg atgatgtcat atatagaaaa attcattgat aaattaacac ctagcatgtt
     5461 aaaaacaatt ttaaatccaa ctttagtatt attaataagt gcgccaatag cattaatagt
     5521 aattggacca ataggaaatt tcttaggaga gggattagct agtataataa atttactaca
     5581 aggaaggtta ggatttataa tggtttgttt attagcagct gcaatgccat ttatcgttat
     5641 gacagggatg catcatgcat tgactcctat attcatatca gcatttgcaa ctacaggaca
     5701 agaatcgcta atattaatat ctcaagtttg tgctaattta gcgcaaggtg gcgcaacatt
     5761 agctgtagca ttaagaagca aagatagtaa gatgaaacag ttagcatcag ctgcatggat
     5821 atcagctatc atgggtataa ctgaaccagc tctttatgga gttacattga aacttaaaaa
     5881 acctgctatg ttagcatcta taggagcagg aatcgcaggg ttatttgcag gaattactca
     5941 tgtgacttta tatgttccac aaaatagtat aatggcagta cttggattat caggggaaaa
     6001 ggggatttca aatatagtaa atggacttat agttatattt atagcattgg ttgctccatt
     6061 tattatgaca tatgtttttg gagttgaaaa aaatgttaaa taaagtacag ataatgtagt
     6121 agaggaagta taatattaac tatttacatt aatagaattt ttattattat tgactataac
     6181 ttgttttgta tttatattga tgcaaagaaa taagttaata ttaataagaa taattattag
     6241 aactgacaaa aagcaacata aaagattgat gaagtatatg gaaataaaaa gttgacaaaa
     6301 tatgtctgat gttttatcat attaattgga attaggtagt aattgtttaa gtacaagcta
     6361 agcttattca ttaataatag cagtatccta ggaaggagta tgcccattat tatggataag
     6421 ctttttttat gcttaaaagg aggataatca tgataattaa taagatatta aacaataatg
     6481 ttgtaatcac attagatgat aatgatgaag aagttatcgt tatgggtaaa ggaattggtt
     6541 atcaaaaatc aaaaggcaat ctaatagata aaactaaagt aaataaagta tttagaatat
     6601 caaataaaga aatatcaaac aaactacaag aattactcaa taatattcct atagaacaca
     6661 tgaaattatc aagtgaaatt atagaatacg cacaaataaa gttaaacaag aagctaaatg
     6721 aaagtattta catatcctta agtgaccata catattctgc aattcaaagg atgaaagaag
     6781 gaataaatgt aaaaaatgca atcctttggg aaattaaaag attttataaa gaagagtttg
     6841 aaattggaat gaaagcacta gatattattg aaaacaaaac aggtataaaa ttaccagaag
     6901 atgaggctgg atttatagcc tttcatatag tgaatgctca gttaagtgaa ggtcatactt
     6961 tggcatctga tattacgaag ttaatacaag aagtacttag catagttagg tatcatttta
     7021 ggatagaatt tcatgaagaa tcagtgtttt attatagatt tataatgcat ttaaagtttt
     7081 ttgcgcaaag attgctttta gatagtgcac atgaaggtga gacagacaaa gaattactaa
     7141 gcattattaa atctaaatat aataaagagt ttgaatgtgt agttaaaatt aaaaatttca
     7201 ttaaaaaaca atataactac atattaacag atgatgagct tatatattta acaatacatt
     7261 tagctaaagt agttaaagac tcaaatatgt aagtgaaata atttttcagt agtatattaa
     7321 gaatgattga aaggagtgat actaacaaaa ttatacttat ggttggatgg taacattgag
     7381 ttggccaaac cttcaaattt caaaaaatta atttaaacga aatatggagg agaaaaatgg
     7441 gaaaatacaa acaattagca caagagatag taaacaatgt tggtggaaaa gaaaatatta
     7501 gtgggttagt acactgtatt acaagattac gttttacttt aaaagatgaa agtatagcaa
     7561 atgacaatgt attaaaaaac atggaaggta ttgttactgt aatgaaaagt ggaggacaat
     7621 atcaagtagt tataggaaat catgttgaag ctgtctataa agatgtagtt gaaataattg
     7681 gtttagatga ttcaagtaca agttcagaaa ctaaaaaatc aggtaatata ctagataaag
     7741 gtatagatat aatatcagga atttttcagc cagtgttagg aataatggca gcttgtggta
     7801 tgttgaaagg atttaatgca ttatttgtag caatgggatt atatagtgat gtatctggtg
     7861 gttatatggt aataaatgca gcaggagatg cattatttac attccttcct ttgttcttag
     7921 gatatacttc agctaagaag tttggattaa aaccaatgtt gggattagca ctaggagctg
     7981 cagtatgtta tcctgctata caaggtagca gtatatcagc aggagcagat gtgatgtaca
     8041 ctttatttaa aggaacaatg tttgcatcac cagtatatat tgatttcttt ggactaccaa
     8101 ttgtatcaat tgattatact ggaacagtcg taccaattat atttatagtg tattttgctt
     8161 ctaggtgtga aaaattattt aataagtgtg ttccaaattt agttaagttt ttctttgtgc
     8221 caatgcttac attattaata acagtgcctg ttgcacttat agttataggc cctatagcaa
     8281 catttggttc tacacttatt tcacaaattg taatttcaat aagagatttt agtccactat
     8341 tggcaggtgc tatagtagga tttacttggc aaattcttgt tatttttggt atgcactggg
     8401 gatttattcc tgtatatata aacaatgtta tgactttagg atatgataat gttatgatgc
     8461 cattctttgc ctgtacattt gcaagttcgg cagttgtgtt ggcaatattt ttcaagacta
     8521 aagataaaaa actaaaagag atggcaatac caaactttat atctggtata tttggagtta
     8581 cagagccagc aatttatgga atattattgc ctttaaagaa accatttata ataagttgta
     8641 ttgctagtgg tattggaggc gctttctatg gattctttaa tcttagaaaa tttataactg
     8701 gaggaatggg aatatttgaa cttccagcaa tgattgaacc agatggggga atgggtaact
     8761 taatagtagc tctttctggt atagctatat caatggtcgt agcttttgta ttaactatga
     8821 ttttatataa agatgagaaa gtagaagagt ctaaaaaagt aagaaataag ggtaaagaag
     8881 aaataaaaga agtcaagtct actaaattag aaagagaaat agtaacaagt cctataaaag
     8941 gtgaagtatt aaaattaagt gatatagagg atgcagcatt tgcatctggt gtactaggtc
     9001 aaggggtggc aataatacct agtgatggaa aagtagttgc tccagtagat ggggtagtta
     9061 caaccttatt tcctagtcta catgctatag ggattctttc tgatacaggt gttgaagtgc
     9121 ttattcatat tggattaaat actattcaat tagagggaag aggttttgag gcatgtataa
     9181 aacaaggtga tagaattaca aaaggtcaaa ctatattaaa ctttgatgtt tatgcaataa
     9241 aagagttggg gtatagtact gtaactccaa ttgttattac aaattcatca caatttttag
     9301 atgtagtaga aacagaaagt aaaaatattg aattagaaga caatctaatt acagtcttat
     9361 tttagtaaag attgaggtat tagcataatc tagtgctttg gttataattt taggaggctt
     9421 tgactatgag ttttaagaat gattttttat ggggaggagc tactgcggcc aatcaatgtg
     9481 aaggtggata caatgaagac gaaagaggat tggcaaatgt agatgtatgt ccaacaggaa
     9541 aagatagaac agcagttatt acagggaaac taaaaatgtt tgattttgat gatgagcatt
     9601 attatccagc taaaactggt attgatatgt atcataatta taaagaagat ataaagttat
     9661 ttgctgaaat gggatttaaa gtatatagaa tgagcattgc atggagtcga atatttccaa
     9721 aaggtgatga agaaacacca aatgaaaagg gacttcaatt ttatgaaaat atatttaagg
     9781 agtgtaaaaa atataaaata gagcctttag tcactattac acactttgat tgtccaatgc
     9841 atttagttaa aaagtatggt gcatggcgta atcgaaaaat gataggtttc tatgagaaat
     9901 tatgcaatgt tatctttaga agatataaag gattagtgaa gtactggcta actttcaatg
     9961 aaataaatat gattttacat gctccattta tgggtgctgg tatttgcttt gaagaaggtg
    10021 aagatgttga aaagataaaa tatcaagctg cccatcatga gcttgtagct agtgcaattg
    10081 caactaaaat agcacatgaa gttgattcaa ataacttaat tggatgtatg tttgcagctg
    10141 gaagtgtata tccttatagt tgtaatccta atgatgtatg ggaagctaca aagttagata
    10201 gagaaaatta cttctttgtg gatgtacaat ctaaaggtaa atatcctaac tatgcgttaa
    10261 agtatatgga gcaaaaaggt attacaccag aaatggaacc tggtgatatt gaattattga
    10321 ataaatatac agtagatttt atttcatttt catattacaa tagccgttgt gttagaaccg
    10381 atgaaaatgc agatgatatg gctgaaggaa acatatttac atctgctaaa aatccatatc
    10441 tttcatacag tcaatgggga tggccaattg acccattagg tttgagaatt acactaaatc
    10501 atgtatatga tagatatgaa aagccactat ttattgtaga aaatggatta ggtgctaaag
    10561 atatagctga tgaaaatggt tatgtagaag atgattacag aattgattat ctaagagaac
    10621 atataaaagc tatgcatgat gcagtttcta tagatggggt cgatttatta ggttatacta
    10681 catgggcacc tattgattta gtaagtgctg gtacaggtga aatggaaaag cgttatggat
    10741 ttatatatgt agatagagac aatagtggta atggaagtct aagaagaatg aaaaagaaaa
    10801 gttttgaatg gtataagaaa gtaattgctt caaatggtga agatttatat tagacaagaa
    10861 atctatgtta aataagaaat ctatattaga caagaaatct atgttaaata agaactttgt
    10921 attaaataag aagagtataa aaattaataa taagtataat ttttaacttt tttaactata
    10981 gaaaatcaat atagaattat tttacattgt attgatgcaa tagtatgatt cacaaataaa
    11041 attttagaaa ataaaattgt taagaagtat gggaagtaag tgcaatttac tttgtaataa
    11101 aagatgaaaa aggcaagctt aggttttaag cttgtctttt ttattatgta taaactatga
    11161 tattttaaaa ttctatgaaa aatttattta atagagaaat taaaaattta atggtaatca
    11221 aattctttac caatgaatat aaaaaatgtc tacgtgttat aatagtttaa actaataaac
    11281 gaaaggtaga tgaatgaata tgaaatacca acatataata gaagttgaca aagaactttg
    11341 cattggatgt gggctttgta aaaatgattg tccagtaaac aatataatta tagaaaataa
    11401 aaagtcagta attaaaaaac aagattgtct aatgtgtgga cattgtgcag caatatgtcc
    11461 cacaaaagct attaccttga caggatttga tgaacctcct atagaactta caaataagcc
    11521 aaagctagat tcagatgaat tactaatggc aattaaatct agaagaagta tacgtaaatt
    11581 taaagataaa gaagtttctt cagaaattat aaagcaaatt attgaggcag gtaggtatac
    11641 ccctagtgct aaaaattcac aagatgtatc atatattgtt ttagacaata aaaagtcaat
    11701 ttatgaaaac gaagcagtga aattttttag aaaaataaaa cctattgcaa atatagctat
    11761 taaatattca aaagaagttg agattgacga taactttttc tttaagcatg ctcctattgc
    11821 aataatgata attacaaaag ataagattag tggttcactt gcagcatcaa atatggcatt
    11881 aatggcagag tcttatggtc taggtgtttt atttagtgga tatttttcag atgtagcaaa
    11941 taattcgcca aaattaaaaa agcttttagg tctaaaacgt agtaatcatg ttcttacaac
    12001 attagtaatt ggatacccag atgttaaata tagacgtact gcacagaaag aagtagcaac
    12061 tgttagatac ttataagaga gggtggattt tatggaaaaa gaatgtcaac aaagaatgca
    12121 agaaataacg tctaaattta aagaatgtcg caaagctatc tctgctatgg gtgatgagac
    12181 tagacaattg attttaattg ctcttttaga gagtgatttt aatggtatac gagtgggaga
    12241 aatcacaaaa aaaacacatc tttctcgtcc tgctgtatct catcatctta agatattaaa
    12301 agaagcagag attgttaatt tgcgtagaga aggaacgaaa aattattatt atcttgattc
    12361 aaaaaaatca caatggaagt cactaacaga gctaataaat cttatatttg ttggaataca
    12421 acatattagt gaaaatgata taagaaaagg tgattaaatt atacttgatt taatacaaaa
    12481 agattgattt aggaactaaa aaattcactt tgagacacta tcttttgaac tatacccatt
    12541 ttaggagacg gttaaaatat gtaaaactgt ataaaacaat gggtatagtt cattttataa
    12601 tggtttaaat attaagaata tattattcta aatagtatct ttctctgttt tgagttttat
    12661 ttttatactc aatagcttca gtggggcaac cacaaataca tgccatacaa tgagtacagt
    12721 tatttttcca aactggtttt ttgtttttta aattaatatt atttaaagga catagctcta
    12781 cacattttcc acagccaatg catttatcag tataatgaaa tcctttggca ctaataattg
    12841 tcttataaaa aactgtattt attataccac ttttaattgt acctcctaag ccactaggag
    12901 taatagtttc aaattcattt tcattgcgta tatcagaaat aatcctatat atttgtttat
    12961 ctgcttcttt aatcatttgt tttgatgttt ctttgtctgt tgtagaaaat aaagctatat
    13021 aattctctgg cattttaatt tctgccatac cttttaattg ccattccttg tatttacata
    13081 gtttttgaat atagtttatg gattttgctg tatctccacc acaagtcatt acaaagtaaa
    13141 ctctgttgct tcctagaaat tttgtttctt ttataaaatc cgtaactact attggcaatc
    13201 tccatgcata agtaggacat acaaatatga atggtttatc tgctgatatt aattcatctg
    13261 ttttttcctc ttttataagt tgatttagtg atatcagttc atcatttaat tcttgtgcaa
    13321 ttttacgagc cacatatcgg ctattaccag ttccgctaaa atataaaatc ataataatat
    13381 ctccctaact attttttatt tattatagta atttattgat atattctatt caaatgtatg
    13441 taaaatttag tagttaagaa aattataaca cattagtaat ttttatactt attggtaaag
    13501 aatttgatta ccattaaatt tagcaacaag acatcaactg gacttgtata tgagaaggga
    13561 taataatttg cttatgaaag attataaata taaaggttat tttaaaggtg tagaaatatt
    13621 tgataatgta aatgacctta acttaaatac tttaacaaca gttagtagat ttgtgcttgt
    13681 ttttttgttt acgataactt aaggaaatat gttacctgaa taataaattt atataataaa
    13741 agtatataaa tatatatatg aatgttaaga ttagttgata gaatttaaat aataaatcca
    13801 atattataaa cataggaggt atgaaaaata tgattaatga gaatttaaaa agtctaagaa
    13861 aaatcaacca gtatacacaa gaagaattag ctgaaaaact taatgtttct agacaatcaa
    13921 tagcaaaatg ggaaagtgga gaatctattc ctgatatatg tagttgcatt aaacttgcaa
    13981 aattgtacaa tgtcaaacta gatgacttag ttaatcattc agaagaaaaa acaggtatta
    14041 tagtacctcc taaaggaaag tttttctttg gagcagttgt agttggtgaa cgtggtcaga
    14101 ttgtcattcc aaaagaagca agagaagtat ttaatataaa tgcaggagat aaattattgg
    14161 tacttggaga tgaggaaaga ggattaggaa ttgttcatca acgtgatttg ataaatttta
    14221 taggtcatgt gggagtagta cgtaaagaag aatgatttaa aaaaattata aaaggaggta
    14281 tgaaatatga gtaaaatagt attttttagc attcctgcat atggtcatac taatcctact
    14341 attgaagtag ttcgtgaatt agtggataga ggaaatgagg tattgtatta ttcttttaat
    14401 gaatttaaag ataaaattga aggtgctgga gcaaaattta tttgttgtga taaatacctt
    14461 ccagaattac tccctggaga tgagaaaaaa attggtaagg attttcctgg attaattgag
    14521 atgatagtag atactactat ttctttagat gaaaaagttt gtagagaact taaagatttt
    14581 aatccagatt gcattgtatc agattcatta agtttttggg gaaagttatt tgcacaaaaa
    14641 cttaatattc catatgtatg ctctacaaca acttttgcat ttaataaaca tacagcaaag
    14701 ttgatgaaac aaaactttat agaaattata cgtatgattt ttggtgtaag acgcattaat
    14761 aaaaaaataa agcttttaca aagaaaaggg tatgaagtaa aaaattttat ttctatagtt
    14821 tctaatgata atgatacgga taccattgta tatacatcaa aagaatttca accaatggta
    14881 gaaaccttct ctagtaagta ttcatttgta ggtccatcag tatcaaagtt gattattgaa
    14941 cctaaagaga gaaaaagaaa gctaatatat atttcgcttg gtacaattaa taataaaaat
    15001 gttagctttt ataaaaactg tataagtgca tttaaagatt ctgatgttga tgtgattatg
    15061 tctgttggta gaagtactga tattaaaagt ttaggaaata taccaaataa ttttgaggtc
    15121 aaaaatagtg ttgaacagat tgctatactt caaaaaactg atgtgtttgt tactcattct
    15181 gggatgaata gtgttaatga aagtttatat tatggagtac ctatggtatt atttcctcaa
    15241 cattcggagc agagaatggt agctaagaga gttgttcatt tgggagcagg aattatgtta
    15301 aaagaggata agtcagaaag tattaaaaaa gcagtatttc aagttataaa tgacaatgaa
    15361 tataaagaaa atgcaactaa actatcaaaa agcttttata atgcaggagg ctcaaaaaaa
    15421 gcagcagatg taatattaca gattatatgt aatagtagac aagttgacat ataatagatt
    15481 tgttaaaaat atatatacat acatgtaatt taatcaaagt actgacagtg gggtctttta
    15541 acctaccagt tggggcatat atattgatgc taaatatgag ggatgttata ttttaataaa
    15601 aaagataaca tccttttttt agtgcattat atcgagtttt aaataataaa tgaaggagga
    15661 ttaatatgaa aaaatataaa gttattttta tagtattaat tataggtatt ataagtgtaa
    15721 cagggtttgt tgtatataaa aactgcatta aaccatggaa agatgctgaa acatatattg
    15781 ataagtatat ggtaaaacaa gatatttcaa aagataatat aaaaagtatt acaaaagaaa
    15841 aagccaagaa ggcaagttac gaaggaatac tatacaaagt gtattacaaa gatgaccctc
    15901 gatatgagta tcaatatttt tatagtgata attattatgc tctatatgta aataaagtaa
    15961 tgttacaaat ttatgatatg gaaaataata ataaactttt aagaagtaat gaggaattaa
    16021 aaagtgtaaa gtatccacta atatatctta aatataagcc agataaatga tttatgacaa
    16081 aatagaatga tttttattaa aatttattta aaaatatcac tagagcgttt aaataaaact
    16141 aaatttaagt a
//
LOCUS       DAMJVG010000088        15979 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.090, whole genome shotgun sequence.
ACCESSION   DAMJVG010000088 DAMJVG010000000
VERSION     DAMJVG010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15979)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15979)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15979
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.090"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            248..397
                     /gene="rpmG"
                     /locus_tag="PC512_003094"
     CDS             248..397
                     /gene="rpmG"
                     /locus_tag="PC512_003094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004402360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HDF2442824.1"
                     /translation="MRVKVTLACTECKQRNYNTTKNKKNNPDRIELQKYCRFCKKHTT
                     HKETK"
     gene            423..644
                     /gene="secE"
                     /locus_tag="PC512_003095"
     CDS             423..644
                     /gene="secE"
                     /locus_tag="PC512_003095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HDF2442825.1"
                     /translation="MAAQKNDGAKTKKRFSLFGYLKETKQELKRVTWPTKKELFKNTS
                     IVLTVVISCTILVWGIDTILSGALALLLK"
     gene            664..1206
                     /gene="nusG"
                     /locus_tag="PC512_003096"
     CDS             664..1206
                     /gene="nusG"
                     /locus_tag="PC512_003096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination factor
                     NusG"
                     /protein_id="HDF2442826.1"
                     /translation="MSELQEASWYVVHTYSGHENKVKATIEKAVKTRGMEDCIRQVVV
                     PTEEVVETTKTGKEKTRQRKVYPSYVLVKMIITDESWYVVRNTKGVTGFVGPGSKPVP
                     LSEDEVKAMGIDTTDPKVVNSDIDFEIGDTVKVSQGPFSGQIGNIEEIDLENREVKVC
                     INAFGKRTLFVIELEGIEKI"
     gene            1245..1670
                     /gene="rplK"
                     /locus_tag="PC512_003097"
     CDS             1245..1670
                     /gene="rplK"
                     /locus_tag="PC512_003097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HDF2442827.1"
                     /translation="MAKKVIGQIKLQIPAGKATPAPPVGPALGQHGVNIMGFTKEFNA
                     KTADQAGMIIPVVITVYQDRSFSFITKTPPAAVLIKKALNLKSGSGEPNKKKVAKMTS
                     AQVREIAELKMPDLNAASVEAAMSMIAGTARSMGVVIED"
     gene            1741..2439
                     /gene="rplA"
                     /locus_tag="PC512_003098"
     CDS             1741..2439
                     /gene="rplA"
                     /locus_tag="PC512_003098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HDF2442828.1"
                     /translation="MAKKGKRYAGALQKVDRTKFYDASEALTLVSDIAGAKFDETVEA
                     HIKLGVDSRHADQQVRGAVVLPHGTGKTKRVLVFAKGEKAKEAEQAGADFVGAEELVQ
                     KIQGENWFDFDIVVATPDMMGVVGRLGRVLGPKGLMPNPKSGTVTFDVAKAIDEIKAG
                     KVEYRLDKTNIIHVPVGKVSFGGEKLTENFTALMDAIIKAKPAAAKGQYLRSITVASS
                     MGPGVKINPARTAE"
     misc_feature    2491..2619
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            2662..3168
                     /locus_tag="PC512_003099"
     CDS             2662..3168
                     /locus_tag="PC512_003099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HDF2442829.1"
                     /translation="MRKAIEIKSEVVSEIVEKLQKSSAAVVVDYKGLTVEEVTELRKQ
                     MREAGVDYKVYKNTLVRRAAKEVGIEQFNDELLVGTNAIAFGYDDPVAPARILKGFMD
                     SHPKMKLKMGIVEGAFYDESKIVEMANIPSREVLIAKLLGSLKAPVSNFAYLIDAIAK
                     KAEGQEEA"
     gene            3226..3591
                     /gene="rplL"
                     /locus_tag="PC512_003100"
     CDS             3226..3591
                     /gene="rplL"
                     /locus_tag="PC512_003100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HDF2442830.1"
                     /translation="MTIEQILEAIENMKVLELNELVKAAEEKFGVSASAPVMVAGAAA
                     GGPAAEEKTEFDVVLTDVGSSKVGVIKAVREITGLGLKEAKEVVDNAPKTVKEGASKE
                     EADQIKEKLEAAGAKVEVK"
     gene            3983..4771
                     /locus_tag="PC512_003101"
     CDS             3983..4771
                     /locus_tag="PC512_003101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDF2442831.1"
                     /translation="MEKLQGKIAVVTAATKGIGLASAEILAKNGATVYLAARSEELAN
                     EVINKISAEGGCAKFVYFNAREEETFTSMIEEVVKKEGKIDILVNNFGSTNPSLDKDL
                     VTGDTDNFFDTVNTNLKSVYLPCKAAIPHMIKNGKGSIVNISSIGSVLPDLSRIAYCV
                     SKAAINSLTQNIATQYAKDNVRCNAVLPGLIATKAALDNMSPEFIKEFLKHVPLNRIG
                     EPDDIAKAVLFYASDDSSFITGDLLEVAGGFGLPTPQFADNILG"
     gene            5242..8958
                     /locus_tag="PC512_003102"
     CDS             5242..8958
                     /locus_tag="PC512_003102"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HDF2442832.1"
                     /translation="MPHPVTIGKRTRMSFSKIKEIADVPNLIEIQVDSYEWFLKEGLK
                     EVFDDISPIEDYTGNLILEFVDYSLDDKPKYDIEECKERDATYCAPLKVKVRLINKET
                     GEIKEQEVFMGDFPLMTERGTFVINGAERVIVSQLVRSPGVYYAEERDKTGKRLISST
                     VIPNRGAWLEYETDSNDVISVRVDRTRKQPVTVLLRALGIGTDAEIIDLLGEDERLSA
                     TLEKDNTKTVEEGLVEIYKKLRPGEPPTVESASSLLNALFFDPKRYDLAKVGRYKFNK
                     KLALCYRIMNKISAEDIINPETGEVFVKAGEKISYDLAKAIQNAGINVVNLLMDDDKK
                     VRVIGNNFVDIKSHIDFDIDDLNIKEKVHYPTLKEILDGYSDEEEIKEAIKSRIKELI
                     PKHILLDDIIASISYEFNIFYNIGNIDDIDHLGNRRIRSVGELLQNQVRIGLSRMERV
                     IKERMTVQDMEAITPQALVNIRPVSAAIKEFFGSSQLSQFMDQTNPLSELTHKRRLSA
                     LGPGGLSRERAGFEVRDVHHSHYGRMCPIETPEGPNIGLINSLGTYAKINEFGFIESP
                     YRKFDKETSTVTDEIHYLTADEEDLFVRAQANEPLTEDGKFVNHRVVCRTVNGAVEMV
                     PESRVDYMDISPKQVVSVATAMIPFLENDDANRALMGANMQRQAVPLVRREAPIIGTG
                     IEYRAAKDSGAVVVARNSGIAERVTADEIIIKREDGNRDRYNLLKFKRSNSGTCINQT
                     PIINKGDQIVKGDVIADGPATDLGEVALGRNCLIAFMTWEGYNYEDAILINERLVKED
                     RLSTIHIEEYECEARDTKLGPEEITRDIPNVGDSAIKNLDDRGIIRIGAEVDSGDILV
                     GKVTPKGETELTAEERLLRAIFGEKAREVRDTSLKVPHGESGIIVDVKVFTRENGDDL
                     SPGVNELVRCYIAKKRKIKVGDKMAGRHGNKGVISRVLPEEDMPFMENGTPLDIILNP
                     QGIPSRMNIGQVLEVHLGLAAKTLGWYVATSVFDGANEYDIMDALEEAGYPRDGKLTL
                     YDGRTGESFDNRITVGYMYYLKLHHLVDEKLHARSTGPYSLVTQQPLGGKAQFGGQRF
                     GEMEVWALEAYGAAHILQEILTVKSDDVVGRVRTYEAIVKGENIPEPGIPESFKVLIK
                     ELQSLCLDVKVLTDEDQEIEVRESVDEDDTIGEFELDVVNHMGEVEESNIIEEIEDDF
                     AENAEDEDIENLEEFTEDDLFEEEIDFDSDDFDM"
     gene            9000..12485
                     /gene="rpoC"
                     /locus_tag="PC512_003103"
     CDS             9000..12485
                     /gene="rpoC"
                     /locus_tag="PC512_003103"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HDF2442833.1"
                     /translation="MFELNNFESIKIALASPEKIRQWSRGEVKKPETINYRTLKPEKD
                     GLFCERIFGPQKDWECHCGKYRRVRYKGVVCDRCGVEVTKSKVRRERMGHIELAAPMS
                     HIWYFKGIPSRMGLLLDMSPRSLEKILYFASYVVVDPGETGLNEKQLLTEKEYRTALE
                     KYGYTFTVGMGAEAVKTLLQNIDLEQQSKDLRAELKDSTGQKKVRTIRRLEVVEAFKK
                     SGNKPEWMILDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLLELGA
                     PDIIVRNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSDMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPELKFYQCGLPKKMALELFKPFVMDKLVKEGYAHNIKSAKSIVEK
                     VKPEVWDVLEDVIKSHPVLLNRAPTLHRLGIQAFEPILVEGKAIKLHPLVCTAYNADF
                     DGDQMAVHVPLSVEAQAEARFLMLSVNNILAPKDGSPITTPSQDMVLGCYYLTIEAQD
                     GAKGTGMVFKDFNELLLAYYNKSVHLHALVKLKVTLEDGRSSLVESTVGRFIFNENIP
                     QDLGFVDRKENPFALEVDFLADKKSLGKIIDKCFRKHGNTETAELLDYIKALGFKYST
                     LGGITVAVDDMSVPEEKKVFIAEAEAKVDKYEKAYRRGLISDEERYEKVIETWTETTD
                     KVTDALMGGLDRLNNIYIMAHSGARGSKNQIRQLAGMRGLMANASGKTVEIPVKSNFR
                     EGLSVLEYFTSSHGARKGLADTAIRTAESGYLTRRLVDVSQDVIVREIDCGTEDTTEI
                     YAIKEGNEVIEEIYDRIVGRYTIDPILNPETGEVIVEADSMIQEDEAETIVALGIEKI
                     RIRTVLNCKTNHGVCSKCYGRNLATGKEVNIGEAVGIIAAQSIGEPGTQLTMRTFHTG
                     GVAGADITQGLPRVEELFEARKPKGLAVITEVSGRVEIDETGKRKEVNVIPEEGETQT
                     YVIPYGSRLKVKQGQMLEAGDPLTQGFINPHDIVRVNGVKGVQEYIVKEVQRVYRLQG
                     VDVNDKHIEVIVRQMLSKVKVEDPGDTDLLPGGYEDVLTFNECNKDAIDKGLRPAVAK
                     RVLLGITKASLATDSFLSAASFQETTRVLTEAAIKGKEDHLIGLKENVILGKLIPAGT
                     GMKKYRNIAVEKIED"
     gene            12774..13196
                     /gene="rpsL"
                     /locus_tag="PC512_003104"
     CDS             12774..13196
                     /gene="rpsL"
                     /locus_tag="PC512_003104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HDF2442834.1"
                     /translation="MPTINQLVRKSRKALEKKSTAPALQKGYNSLNKKVTDASAPQKR
                     GVCTSVKTVTPKKPNSALRKVARVRLTNGIEVSAYIPGEGHNLQEHSVVLIRGGRVKD
                     LPGVRYHILRGTLDTAGVDKRRQSRSKYGAKRPKEAKK"
     gene            13320..13790
                     /gene="rpsG"
                     /locus_tag="PC512_003105"
     CDS             13320..13790
                     /gene="rpsG"
                     /locus_tag="PC512_003105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001137493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HDF2442835.1"
                     /translation="MPRKGNIPKREVLPDPMYGSKVVTKLINNLMVDGKKGKSQRIVY
                     DAFAIVAEKTGEEALEVFNKAMDNIMPVLEVKARRVGGANYQVPIEVRPERRQTLGLR
                     WLVKYTRARGEKGMVEKLAKEIMDAANNTGASVKKKEDTHKMAEANKAFAHYRW"
     gene            13839..15905
                     /gene="fusA"
                     /locus_tag="PC512_003106"
     CDS             13839..15905
                     /gene="fusA"
                     /locus_tag="PC512_003106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HDF2442836.1"
                     /translation="MARKFPLERTRNIGIMAHIDAGKTTTTERILFYTGQTHKIGETH
                     EGASQMDWMEQEKERGITITSAATTASWKDHRINIIDTPGHVDFTVEVERSLRVLDGS
                     VAVFCAKGGVEPQSENVWRQAETYGVPRIAFVNKMDILGADFYNVVSMMKSRLNSNAV
                     PMQLPIGKEDSFIGIIDLLKMDAVIYKDDLGVEMEETDIPEDMKELAAEWREKLVESV
                     AETDEELMMKYLEGEELTIDELKVAIRKATIACEMNPVFCGTAYRNKGVQLVIDAVLD
                     YLPAPTDIPAIKGILADGEEAERHSSDEEPFSALAFKIMTDPFVGKLAFFRVYSGTLE
                     SGSYVLNATKNKRERIGRILQMHANTREEITKVYAGDIAAAVGLKDTTTGDTLCDPAN
                     PIILESMEFPEPVISVAIEPSSKAAQEKMGIALQKLAEEDPTFTVKTDQETGQTIISG
                     MGELHLEIIVDRLLREFKVEAKVGAPQVAYRETITQPVDVEYKYSKQSGGRGQYGHVK
                     IRVAPQEPGEGYKFTNKTVGGSVPKEYVGPVDMGIQGAMQSGIVAGYPVVDVAVELYD
                     GSYHEVDSSEMAFKMAGSMAFKDAMKKGNAVLLEPYFKVEVVTPEDYMGDVMGDLNSR
                     RGLIQGMEARSGAQVINAFVPLSEMFGYSTDLRSSTQGRATYTMIFDHYEQVPASVAK
                     KIAEGK"
BASE COUNT         6256 a         1987 c         3251 g         4485 t
ORIGIN      
        1 ctttactaaa ctgatggatt aaaaggaata acaaaaagag gggttatgct cctctttttt
       61 taacatagaa atacaaaaac attgacacag cataggattt tgtgataact tatacaaggt
      121 aatgattata ggaagttaat aatatcttga atactgtaga tttttaataa atacatattt
      181 taaagatatt atattcacat atattaacaa tatatattat tgtattacaa agttggaggt
      241 gtatcagatg agagttaaag taactttagc atgtacagag tgtaagcaaa gaaactacaa
      301 cactactaag aataagaaaa ataatccaga cagaatagaa ttacaaaaat attgtagatt
      361 ctgtaaaaag catacaactc ataaagaaac aaaatagttt tttataagga tgtgagtatg
      421 gaatggctgc ccaaaaaaat gacggtgcaa aaactaaaaa aaggtttagt ttgtttggat
      481 acttaaaaga aactaaacaa gaattaaaaa gagttacatg gccgacaaaa aaggaactgt
      541 ttaaaaacac aagtatagtt ttaactgtag ttatttcatg cactatatta gtatggggta
      601 tagacactat attatctggt gcactagcgt tattactaaa atagacgaaa agaggtaagt
      661 taaatgtcag aattacaaga agcaagttgg tatgtagttc atacctattc gggacatgaa
      721 aataaagtta aagctacaat tgagaaagca gttaaaacaa gaggtatgga agactgcata
      781 agacaagtag ttgttccaac agaagaagta gtggaaacta ctaaaactgg aaaagaaaaa
      841 actagacaac gtaaagttta tccaagttat gttttggtta aaatgataat aactgatgaa
      901 tcttggtatg tagtaagaaa tactaaggga gttacaggtt tcgttggacc tggttcaaaa
      961 ccagtgccat taagtgaaga cgaagtcaaa gctatgggga tagacacaac agaccctaaa
     1021 gtagtaaata gcgatattga ttttgaaata ggagatacag taaaagtatc tcaaggacca
     1081 tttagtggac aaataggtaa catagaagaa attgacttag aaaatagaga agtcaaagta
     1141 tgcataaatg catttggtaa aaggactcta tttgtaatag agcttgaagg tatagaaaaa
     1201 atctaatact atattataga aaaatctgag gaggtgcgct caaaatggct aaaaaagtta
     1261 taggtcaaat aaaattacaa atacctgcag gaaaggctac tccagcgcca ccagttggac
     1321 cagcattagg acaacatggt gttaatataa tgggattcac aaaagaattt aatgctaaaa
     1381 ctgcagatca agctggaatg ataataccag ttgttataac tgtatatcaa gatagatcat
     1441 tcagttttat aacaaaaact ccaccagctg cagttttaat taaaaaagca ttaaacttaa
     1501 aatcaggttc tggagaacca aacaagaaaa aagttgctaa aatgacttca gctcaagtaa
     1561 gagaaatagc tgaattaaag atgcctgact taaatgctgc atcagtagaa gctgctatga
     1621 gtatgatagc tggtactgct agaagcatgg gtgttgtaat cgaagactag ttaaaagata
     1681 cacttttttt tataaagtgg gaggctagaa gccgaaatta accacgagga ggaaaataaa
     1741 atggctaaaa aaggtaaaag atatgcaggt gcattacaaa aagtagatag aactaaattt
     1801 tatgatgcat cagaagcatt aacattagtt tcagatatag ctggagctaa atttgatgag
     1861 acagtagaag cacacattaa attaggtgtt gactcaagac atgctgacca acaagtaaga
     1921 ggtgcagttg tattacctca tggaactggt aaaacaaaaa gagttttagt ttttgctaaa
     1981 ggtgaaaaag ctaaagaagc tgaacaagct ggtgctgact ttgtaggagc tgaagaatta
     2041 gttcaaaaaa tacaaggtga aaactggttt gactttgata tagtagttgc tactccagat
     2101 atgatgggtg tagtaggtag attaggtaga gtattaggac ctaaaggttt aatgccaaac
     2161 cctaaatcag gaacagttac atttgatgta gctaaagcta tagatgaaat aaaagctggt
     2221 aaagttgaat acagattaga caaaactaac ataatacacg ttccagtagg aaaagtatca
     2281 tttggtggag aaaaattaac tgaaaacttt actgcattaa tggatgctat aataaaagct
     2341 aaaccagctg ctgctaaagg acaatattta agaagtataa cagtagcttc ttcaatggga
     2401 cctggagtta aaataaaccc agcaagaaca gctgaataat aaaactgttg acacaggttg
     2461 acaaaaatgt tattatatca cttgtcaatg taaaaaagaa tagatttgcc gtagatagtg
     2521 ggtgcgaaag cttaatatcc cgccgaggtt ttagataaat tgagattact aaagcttttg
     2581 atgtctactt ttggcaacaa aagcttttta taatgttgcg gtaaatacta agcctatttg
     2641 gtgaaggagg tgcacatcta tatgagaaaa gctatagaaa ttaaatcaga agttgtttct
     2701 gagatagttg aaaagttaca aaaatcttct gctgctgttg ttgtagatta caaaggatta
     2761 acagttgaag aagtaactga gttaagaaaa caaatgagag aagctggtgt agattacaaa
     2821 gtatacaaaa atactttagt tagaagagca gctaaagaag ttggtataga gcaatttaat
     2881 gatgaattat tagttggaac taatgccata gcatttggat atgatgatcc agttgctcca
     2941 gctagaatat taaaaggatt catggattct catccaaaaa tgaaattaaa gatgggtatt
     3001 gtggaaggtg cattctatga tgaatctaag attgttgaaa tggctaacat accatcaaga
     3061 gaagttctta tcgctaaatt acttggtagc ttaaaagctc cagtatcaaa cttcgcatac
     3121 ttaatagatg caatagcgaa aaaggcagaa ggtcaagaag aagcttaatt gcttaactaa
     3181 aaaattataa atattaattt gaaataaaat tcggaggtgc taaaaatgac aatagaacaa
     3241 atattagaag ctatagaaaa tatgaaagtt ttagaattaa atgaattagt taaagctgct
     3301 gaagaaaaat tcggtgtatc agcttcagct ccagtaatgg tagctggtgc agctgctggt
     3361 ggaccagctg ctgaagaaaa aactgagttt gatgtagtat taactgacgt tggttcttca
     3421 aaagttggag ttataaaagc agttagagaa ataacaggat taggattaaa agaagctaaa
     3481 gaagtagttg acaatgctcc taagacagtt aaagaaggag cttctaaaga agaagctgat
     3541 caaataaaag agaaattaga agctgctgga gctaaagtag aagttaagta gtttctttaa
     3601 aaagataccc attgggtatc tttttttatt tataaaaaac tataaagaaa gtatttggaa
     3661 ttataaagaa agtattttta taaaataaaa aaaatttata taatagtact aaattaaggg
     3721 tatcatatat ggtgtaatgg tattttaatt taacattatt atcaaattaa aatataaaca
     3781 attgttgtaa tgtctatata taaagtatat aattaaacta aaatgtaaaa ttttacattt
     3841 tagtttaaaa aaatacacga atgttttata aataaaatgt aataaataat taattaacaa
     3901 atataaattt taaaataagt tagatattta gaaaaatcga aatttgtagg atttaaagga
     3961 catattcaag gaggagttaa taatggaaaa attacaagga aaaattgcag tagttactgc
     4021 agcaacaaaa ggtattggat tagcatcagc agagatatta gcaaaaaatg gagcaactgt
     4081 gtacttagca gctcgttcag aagaattagc taatgaagtt ataaataaaa taagtgcaga
     4141 aggtggttgt gctaagtttg tttactttaa tgctcgtgaa gaagagacct ttacctcaat
     4201 gatagaagag gtagttaaaa aagaaggtaa gatagatata cttgtaaaca attttggttc
     4261 aacaaaccct tctcttgaca aagaccttgt aactggggat acagataatt tctttgacac
     4321 agtaaatact aatttaaaaa gtgtgtattt accatgtaaa gcagcaattc ctcatatgat
     4381 aaagaatgga aaaggaagta tagtaaatat atcaagtata ggttcagtat tacctgattt
     4441 atctagaata gcttactgtg tatcaaaagc agcaatcaac tcattaactc aaaatatagc
     4501 tacacaatat gctaaagaca atgttagatg taatgctgta cttccagggc ttattgcaac
     4561 taaagcagca ttagacaata tgtctccaga gttcataaaa gaatttttaa agcatgttcc
     4621 tttaaatcgt ataggggaac cagatgatat agcaaaagct gttctattct atgctagtga
     4681 tgactcatca tttataacag gggatttact tgaagttgca ggaggatttg gtttacctac
     4741 tccacaattt gcagataata tattaggata attaaattac taatatgcaa tgaaagctta
     4801 tgcattagtt atagtagaaa tgatattttt ataaaggcca tagatataat ttatattgga
     4861 aaggtttgag gttcaaaatt ccaagttaaa tttatttatg gtctttattt tgtatatttt
     4921 aataaattgt atatatttgt ataaatgtaa ttatttacaa tcattttaat atggaattat
     4981 aattaaatag gggggatggt acttgtataa aattttttat agaaaattag acctataaat
     5041 gaaaaatatg gattttatat tggaaaattg tacataatac ataatatatg cttaaaataa
     5101 tttacaaaaa atcaaaaata atgcatagtt tacatataag ataaaaaata tattgaaaaa
     5161 tacttgacat tatgctaaaa ttattagatg cgttagaatg aactattgtt ttatttttaa
     5221 ttattgagag gtgaaaagtg aatgccacat cctgtcacga taggtaaaag aactagaatg
     5281 agcttttcta aaattaagga aatagctgat gtgccaaatc ttatagaaat tcaagtagat
     5341 tcctatgagt ggtttttaaa agaaggttta aaagaagtgt ttgatgatat ttcaccaata
     5401 gaagattata ctggtaatct tatattggaa tttgtcgact attctctaga tgataaacca
     5461 aagtacgata tagaagagtg taaagagaga gatgctacat attgtgcacc tctaaaggtt
     5521 aaggtaagac ttataaataa agaaacaggt gagataaaag aacaagaagt gtttatgggt
     5581 gacttccctt taatgacaga aagaggaact ttcgttataa atggagcaga aagagttata
     5641 gtaagtcaat tagttagatc tcctggtgtt tactatgcgg aagaaagaga taaaacaggt
     5701 aagagattga tttcatctac tgtaattcct aatagaggag catggttaga atatgaaaca
     5761 gattctaatg atgtaatatc tgtaagagtt gatagaacaa gaaaacaacc agttacagtt
     5821 ttacttagag ctttaggaat aggaacagat gcagagataa ttgacctttt aggagaagat
     5881 gagagattat ctgctacatt agaaaaagat aatactaaga cagtagaaga aggtcttgta
     5941 gagatataca aaaaattaag accaggtgaa cctcctactg tagaaagtgc atcatcttta
     6001 ttaaatgctt tattctttga cccaaaaaga tatgacctag caaaagttgg tagatataaa
     6061 ttcaataaga aacttgcttt atgttacaga ataatgaata aaatttcagc agaagacata
     6121 ataaatccag aaactggaga agtatttgta aaagctggag aaaaaataag ctatgatttg
     6181 gctaaagcca tacaaaatgc aggtataaat gtagtaaatc tactaatgga tgatgataaa
     6241 aaagttagag ttataggaaa taattttgtg gatattaagt ctcacattga ttttgacata
     6301 gatgatttaa acataaaaga aaaagtacat tatccaactt taaaagaaat tttagatgga
     6361 tatagtgatg aagaagaaat aaaagaggct ataaaatcaa gaattaaaga acttatacca
     6421 aaacatatat tattagatga tataatagct tcaataagtt atgagttcaa tatattctat
     6481 aatataggaa atattgatga tatagatcac ctaggaaaca gaagaataag atctgtaggt
     6541 gaattgttac aaaatcaagt tagaattggt ctttcaagaa tggaaagagt tataaaagaa
     6601 agaatgacgg ttcaagatat ggaagctata acgcctcaag cgttagttaa cataagacca
     6661 gtttcagctg caataaaaga attttttggt agttctcagt tatctcagtt catggatcaa
     6721 acaaatcctc tatctgagtt aacgcataag agaagattat cagcccttgg gcctggaggt
     6781 ctttcaagag aaagagctgg attcgaagtg cgtgacgttc accattcaca ctatggtaga
     6841 atgtgtccaa tagagactcc agagggacca aatatcggtc ttataaactc tctaggaact
     6901 tatgcaaaaa taaatgaatt tggatttata gaatcaccat atagaaaatt tgataaagaa
     6961 acatcaacag ttactgatga aatacattat ttaactgctg acgaagaaga tttattcgta
     7021 agagctcagg caaatgagcc attaacagaa gatggtaaat tcgtaaacca tagagttgtt
     7081 tgtagaactg taaatggtgc tgttgaaatg gttcctgaaa gtagagtaga ttacatggat
     7141 atatctccta agcaggttgt atctgttgcc actgctatga tacctttctt agaaaatgat
     7201 gatgccaacc gtgcccttat gggagcgaac atgcagcgtc aggcagtgcc tctagttaga
     7261 agagaagcac caattatagg aactggtata gaatacagag cagcaaaaga ctctggagca
     7321 gttgttgttg ctagaaattc tggtatagca gaaagagtaa cagcagatga aataattata
     7381 aaaagagaag atggaaacag agatagatat aatctactta agtttaaacg ttcaaactca
     7441 ggtacttgta taaatcaaac acctataata aataagggtg accagatagt aaaaggtgat
     7501 gttatagcag atggtccagc aactgattta ggagaagttg cacttggaag aaactgtctt
     7561 atagcattca tgacttggga aggttataac tacgaggatg ctatattaat aaatgaaaga
     7621 ttagttaaag aagatagatt atcaacaatt catatagaag aatatgaatg tgaagctaga
     7681 gatacaaaac tagggccaga ggaaataact agagatatac ctaatgttgg agatagtgca
     7741 attaagaact tagatgacag aggtataata agaataggtg cagaagtaga ctcaggtgat
     7801 atattagttg gtaaagtaac tccaaaagga gaaactgaac ttactgctga ggaaagatta
     7861 cttcgtgcaa tatttggaga aaaggctaga gaagttagag atacttcact taaagtgcct
     7921 catggtgaat ctggtataat agttgatgta aaagtattta ctagagaaaa tggagatgat
     7981 ttatctccag gagtaaatga attagtaaga tgctatatag ctaaaaagag aaaaataaaa
     8041 gttggagata aaatggctgg tcgtcatggt aataaagggg ttatctcaag agtattacct
     8101 gaagaagata tgccattcat ggaaaatgga acaccactag acataatact taacccacaa
     8161 ggtataccat cacgtatgaa cattggtcag gttttagaag ttcatttagg acttgctgct
     8221 aagacattag gatggtatgt agcaacatca gtattcgatg gtgctaatga gtatgacata
     8281 atggatgctc ttgaagaagc tgggtatcct agagatggta aattaacttt atatgatggt
     8341 agaacaggtg agtcttttga caacagaata actgttggat atatgtacta cttgaaacta
     8401 catcacttag tagatgaaaa actacatgca agaagtactg gaccatactc attagttact
     8461 caacagccac taggtggtaa agcacaattt ggtggacaaa gatttggaga gatggaggtt
     8521 tgggctctgg aagcatatgg agctgctcac atacttcaag aaatacttac tgttaagtct
     8581 gatgacgttg taggtcgtgt tagaacatat gaagctatag ttaaaggtga aaatatacct
     8641 gaaccaggaa tcccagaatc atttaaggtt cttataaaag aacttcaaag tttatgctta
     8701 gatgtaaaag tattgacaga tgaagaccaa gaaatagaag taagagaatc tgtggatgaa
     8761 gatgatacaa taggtgaatt tgagctagat gttgtaaatc atatgggaga agttgaagaa
     8821 agtaatataa tagaagaaat tgaagatgat tttgcagaaa atgcagaaga tgaggatata
     8881 gagaatttag aagaattcac tgaagatgat ttatttgaag aagaaataga ttttgatagt
     8941 gatgactttg atatgtaaat ttaattaatg taaatctcaa atagaaggga gagaactcct
     9001 tgtttgaatt aaacaatttc gagtcgataa aaatagcatt ggcttctcca gaaaaaataa
     9061 gacaatggtc taggggagaa gttaaaaagc cagaaactat aaattaccgt actttaaaac
     9121 cagaaaaaga tggtcttttc tgtgaaagaa tatttggacc acaaaaagac tgggagtgcc
     9181 actgtggtaa atatagaaga gttagatata aaggtgtagt ttgtgataga tgtggagtag
     9241 aagtaactaa atcaaaagta agaagagaga gaatgggaca tatagagcta gcggctccta
     9301 tgtctcacat ctggtacttc aaaggtatac caagtagaat gggactttta cttgatatgt
     9361 caccaagatc gttagaaaaa atattatact ttgcctcata tgtggtagtt gatccaggag
     9421 agactggatt aaatgaaaaa caattgctta cagaaaaaga atacagaact gctcttgaaa
     9481 agtatggata tacttttact gtaggaatgg gtgctgaagc tgtaaagaca ttactacaaa
     9541 atatagattt agagcaacaa agtaaagacc taagagcgga gttaaaagat agtacagggc
     9601 aaaagaaagt tagaacaata agaagattag aagttgtaga ggcatttaaa aagtctggaa
     9661 ataaaccaga atggatgatt ttagatgcaa taccagtaat accaccagat ttaagaccaa
     9721 tggtacaact tgatggtgga agatttgcga cttcagacct aaatgattta tatagaagag
     9781 ttataaatag aaacaataga cttaaaagat tattagagct tggagctcca gatataattg
     9841 taagaaatga aaaaagaatg cttcaagaag ctgttgatgc attgatagat aatggtagaa
     9901 gaggtagacc tgtaacagga cctggaaata gaccacttaa atctttatca gatatgttaa
     9961 aaggtaagca aggtcgtttc cgtcaaaact tacttggtaa gcgtgttgac tactcaggac
    10021 gttctgttat agttgttgga ccagaactta aattttatca atgtggactt ccaaagaaga
    10081 tggcattaga attattcaag ccatttgtta tggataaatt agttaaagaa ggttatgcac
    10141 ataatataaa aagtgcgaaa tctatagtag aaaaagttaa gccagaagtt tgggatgttt
    10201 tagaagatgt tataaaaagt catccagttc ttcttaaccg tgcaccgact ctacatagat
    10261 taggtataca agcatttgaa ccaatcttag ttgaaggtaa ggctataaaa ctacatcctc
    10321 ttgtatgtac agcttataat gcagactttg atggtgacca aatggcagtt catgtacctt
    10381 tatcagtaga agcacaagca gaagcaagat tcttaatgct ttctgtaaat aatatacttg
    10441 ctcctaaaga tggttcacct ataactactc catctcagga tatggtttta ggttgctatt
    10501 atctaacaat agaagcccaa gatggagcta aaggaacagg tatggtattt aaagacttta
    10561 atgaactatt acttgcttat tacaataaat cagttcatct acatgcatta gtgaaactta
    10621 aggtaacact tgaagatgga agaagttcat tggttgaaag tactgttggt agatttatat
    10681 ttaatgaaaa tatacctcaa gacttaggtt ttgtagatag aaaagaaaat ccatttgcac
    10741 ttgaagttga tttcttagca gataaaaaat ctcttggtaa aataatagat aaatgcttta
    10801 gaaaacacgg aaatacagaa acagctgaat tactagatta tataaaagct ctaggattta
    10861 aatattctac attaggtggc ataacagttg ctgttgatga tatgagtgtc ccagaagaaa
    10921 agaaagtatt tatagctgag gcagaagcta aagttgataa gtatgaaaaa gcatacagaa
    10981 gaggtctaat ctctgatgaa gaaagatatg aaaaagttat agagacatgg acagaaacaa
    11041 ctgataaagt tactgatgct cttatgggtg gactagatag attaaataat atatatataa
    11101 tggcacattc aggagccaga ggttctaaaa accaaattag acagctggca ggtatgcgtg
    11161 gtcttatggc aaatgcatct ggtaaaacag ttgagatacc agttaaatct aatttccgtg
    11221 aaggtttatc agtactagaa tactttacat cttcacatgg tgccagaaaa ggtcttgccg
    11281 atacagctat acgtacagct gaatctggat atttaacaag aagacttgtt gatgtaagtc
    11341 aagatgttat tgtaagggaa atagattgtg gaacagaaga tactacagag atttatgcta
    11401 taaaagaagg aaatgaagtt atagaagaga tatatgatag aattgtagga agatatacta
    11461 tagaccctat attaaatcct gaaactggag aagttatagt tgaggctgat tcaatgatac
    11521 aagaagatga agcagaaact atagtagctt taggaattga aaaaattagg ataagaacag
    11581 ttcttaactg taaaactaat catggagttt gttctaagtg ttatggtaga aacttggcaa
    11641 caggaaaaga agttaatata ggtgaagcag ttggtataat agcagctcaa tctatcggtg
    11701 agccgggtac tcagcttaca atgcgtacat tccatactgg aggagttgca ggagctgata
    11761 taactcaagg tctaccaagg gttgaagaat tatttgaagc tagaaaacca aaaggattag
    11821 ctgtaataac tgaagtatct ggtagagttg aaattgatga aacaggaaag agaaaagaag
    11881 taaatgtaat accagaagaa ggcgagactc aaacatatgt aattccatat ggttctagat
    11941 taaaagttaa gcaaggtcaa atgctagagg ctggagaccc tctaacacaa ggatttataa
    12001 atcctcatga tatagtaaga gtaaatggtg ttaagggagt tcaagaatat atagttaaag
    12061 aagttcaaag agtgtataga cttcaagggg ttgatgttaa tgataagcat atagaagtta
    12121 tagtaagaca aatgctatct aaagtaaaag ttgaagaccc aggagataca gatttattgc
    12181 caggtggata tgaagatgta ttaacattca atgaatgtaa taaagatgct atagataaag
    12241 gtctaagacc agcagttgct aaaagagttt tacttggtat aactaaagca tctcttgcaa
    12301 ctgattcatt cttatcagca gcttctttcc aagaaacaac aagagtatta acagaggcag
    12361 caataaaagg taaagaagac cacttaatag gacttaaaga aaatgttata ttaggtaagt
    12421 taataccagc aggaacagga atgaagaaat atagaaatat agctgttgaa aaaattgaag
    12481 attaatagca tatagagtaa agaaatcttg acaaccatta tttgtggtgt taaaatagta
    12541 aagtgtgttg tttaaaagta cactaagggc ttgaacaagt tcttagtgac ttttagatgg
    12601 caataaatga gaactaaaaa gcatcaagct agaaaagtgc taatatcaca tatttatgtg
    12661 ttatagacat taaattgtaa gtaacgaatg ttacaatcag tcagtatgaa tattcatatt
    12721 gatgtagttg gcggtcactg ataagatcga aaatttggaa ggaggtgcag atgatgccaa
    12781 caattaacca attagttcgt aaaagtagaa aagcgctaga gaagaaatct actgctccag
    12841 cattacaaaa aggttacaac tctttaaata agaaagtaac tgacgctagt gccccacaaa
    12901 aaagaggggt ttgtacttca gtaaaaacag ttactcctaa gaagcctaac tcagctttaa
    12961 gaaaagttgc cagagttaga ttaactaatg gtatagaagt ttctgcttat ataccaggag
    13021 aaggacacaa cttacaagag catagtgttg ttcttataag aggaggaaga gtaaaagacc
    13081 ttccaggggt tagataccat atactaagag gtactctaga tacagcaggt gttgataaga
    13141 gaagacaatc aagatctaaa tacggtgcga agagacctaa agaagctaaa aagtaaaaac
    13201 aattaatgat tgattatagt tcggtgcttt aaatatatat atatttacgg catcacggca
    13261 ttaaatgatt tatgtcgagt acctatgatt taagttaaat aattaaggag ggaagcgaaa
    13321 tgccaagaaa aggtaatatt ccaaaaagag aagttttacc agatcctatg tatgggagta
    13381 aggtagttac taaattaata aataatctaa tggtagacgg aaaaaaagga aagtctcaaa
    13441 gaatagttta tgatgctttc gcaattgttg ctgaaaagac aggagaagaa gctttagaag
    13501 tatttaataa agcaatggat aatataatgc ctgttttaga agtaaaagca agaagagttg
    13561 gtggggcaaa ctaccaagtg ccaatcgaag ttagacctga aagaagacaa acattaggtt
    13621 taagatggct agtaaaatat actagagctc gtggagaaaa aggaatggtt gaaaagctag
    13681 ctaaagagat aatggacgca gctaacaaca ctggagcttc agttaagaaa aaagaagata
    13741 ctcataaaat ggcagaagct aataaagcat ttgctcatta cagatggtag gatatataga
    13801 tatcttataa aattgaggat atcataagga ggataaccat ggctagaaag tttcctttgg
    13861 aaagaactag gaatatagga atcatggctc atatagatgc aggaaaaact actactacag
    13921 aaagaatcct gttttatact gggcaaactc ataaaatagg agaaactcat gaaggagctt
    13981 ctcaaatgga ctggatggag caagaaaagg aaagaggtat aacaataact tctgccgcta
    14041 ctactgcttc atggaaagac catagaataa acataataga tactcctgga cacgtggact
    14101 tcacagttga ggttgaaaga tctctaagag ttcttgacgg ttcagttgct gtattctgtg
    14161 caaaaggtgg ggttgagcct caatcagaaa atgtatggag acaagctgaa acttatggag
    14221 tacctagaat agcttttgta aataaaatgg atatattagg tgcagatttc tacaatgttg
    14281 taagcatgat gaaatctaga ttaaattcta atgcagttcc tatgcaatta ccaataggta
    14341 aagaagattc atttataggt ataatagact tattaaaaat ggatgctgtt atatacaaag
    14401 acgacctagg ggttgaaatg gaagaaacag atataccaga agatatgaaa gaattagctg
    14461 ctgagtggag agaaaaatta gttgaatcag tagctgaaac tgatgaagaa ttaatgatga
    14521 aataccttga aggtgaagaa cttactatag atgaattaaa agttgctata agaaaagcta
    14581 ctatagcttg tgaaatgaac ccagttttct gtggtacagc ttatagaaac aaaggtgttc
    14641 agttagtaat agatgcagtt ttagattact taccagcgcc aactgatata ccagctataa
    14701 aaggtatatt agcagatgga gaagaagctg aaagacattc ttctgatgaa gagccattct
    14761 ctgcattagc attcaaaata atgactgacc cattcgttgg aaaactagcg ttcttcagag
    14821 tttattctgg aacattagaa tcaggttctt atgttttaaa tgcaactaag aataagagag
    14881 aaagaattgg tcgtatatta caaatgcatg ctaatacaag agaagaaata actaaagtgt
    14941 atgctggaga tatagcagca gcagtaggat taaaagatac tactactgga gacacattat
    15001 gtgaccctgc taatccaata atacttgaat ctatggaatt ccctgagcca gttatatctg
    15061 ttgctataga accaagttct aaagcagctc aagaaaaaat gggtatagct cttcaaaaat
    15121 tagctgaaga agacccaact ttcacagtta agactgacca agaaacagga caaactataa
    15181 tatctggtat gggtgaatta cacttagaga taatagtaga tagattatta agagaattta
    15241 aagtagaagc taaagttggt gcaccacaag ttgcatatag agagactata actcaaccag
    15301 ttgatgttga atacaagtac tctaagcaat caggtggtag aggacaatac ggtcacgtta
    15361 agattagagt tgctcctcaa gagccaggtg aaggatacaa attcacaaac aaaactgttg
    15421 gtggatcagt accaaaagaa tatgttggtc cagttgacat gggtatacaa ggagctatgc
    15481 aatctggtat agttgctgga tatccagttg tagacgttgc tgttgagtta tatgatggtt
    15541 cttaccatga ggttgactct tctgagatgg cgtttaagat ggctggttca atggcattca
    15601 aagatgctat gaagaaaggt aatgcagttc ttttagagcc ttacttcaaa gtagaagttg
    15661 ttactccaga agattacatg ggagatgtta tgggtgactt aaactcaaga agaggattaa
    15721 tccaaggtat ggaagctaga agtggtgcac aagttataaa tgcattcgtt ccactttcag
    15781 aaatgtttgg atactcaaca gacctaagat cttcaactca aggtcgtgca acttacacaa
    15841 tgatattcga tcactatgag caagttccag cttcagttgc taagaaaata gctgaaggaa
    15901 aataatttaa aaataattaa taatataaat ataaaaaata atcagctaga tgagagatat
    15961 ctctcatcta gcacaagat
//
LOCUS       DAMJVG010000089        15948 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.091, whole genome shotgun sequence.
ACCESSION   DAMJVG010000089 DAMJVG010000000
VERSION     DAMJVG010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15948)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15948)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15948
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.091"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            369..2603
                     /locus_tag="PC512_003107"
     CDS             369..2603
                     /locus_tag="PC512_003107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF2442837.1"
                     /translation="MQNHNYIKMLNKKVEVLSKELDSRNFKLKTLNEIDFFSKIPNRE
                     FMYQHIDDCISKNIHIGIMLLNIDNFKLFNDIYGYLVGENLLITLTQNLLHFIPESKG
                     IVAYLKGEGFLIVLPNVSNKELNNMGATIIESARELKIKLPNEKEIYSNVTFSIGSTI
                     WNGEPNMTTLMLFNQVYSALKKAKSEGKNRYILFDFKDNSFYNKLENDKEFLSEISHV
                     LQTKQIEVFYQPLYNIKNNTIVGCEALARWRHPIKGLLTPDKFIPLFEQFGLITELDL
                     HLFEENCKNIRRWIDNNDVFVPICCNFSRLHFFNPNFPSMLKGITEKYSVSTSNFSIE
                     ITENILIENTNTIIQQLAELRSYGFSVSMDDFGSGYSSFGMLQNLPFDIIKIDRIFLS
                     HNLNDFKNTTILYSIINIARALGMLTVCEGVETEQHVEFIKSINCDIAQGYYYAKPME
                     CKEFEKLLSKENNSEKMFIKYSDIGKSLIEKIFDGFFIMQDMKKLRANVTEDIQWFDF
                     YNKTEITSFPKVIEHFEKHIKGKKFSILYKSITPHNTESDSLLISGEAVLSDEASEHQ
                     KYSNFYFSANCIISENKLLLAKLHLDLIKTAGYINEFESYSIPKMTNTHLDESNILSQ
                     FYSMLPVGIIRYDLFGDMIITYMNEEMFDIIGYTKEQFFGEMGGNLRAIVHPDDLDFV
                     YKKSLDMIDTNKIEPFLYRFIKRDGQIVTVMYTQCNLSAIDGRSIAQGMYVDVNKIKN
                     LTKI"
     gene            2634..3467
                     /locus_tag="PC512_003108"
     CDS             2634..3467
                     /locus_tag="PC512_003108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF2442838.1"
                     /translation="MFKEIFLRTFPGFLIIRDSNYRIIFINDNLKNLIKSYMQDNPLG
                     MTNIEIAKKLPDNIAKFFTDSHNIQLDWEKNYPYDKISNWILEFKKDTTSYWNVLEYK
                     VDVDEKTYIITMANDITKLYEENKRNLHYSITDPLTGAYNRKYLNDRFDIFIGDYIVL
                     IDLDNFKMINDYEGHNVGDKILCDFVSLLNKELINSTSIIRLGGDEFIVIFSSDVDKN
                     YVYSQLEALRENFLKVFSKYKYLSFSYGVDTVKRNLKLTIVELDKKMYKNKKKFDKND
                     Y"
     gene            3707..5440
                     /locus_tag="PC512_003109"
     CDS             3707..5440
                     /locus_tag="PC512_003109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDF2442839.1"
                     /translation="MSILLKKAPKLAKHIITSFYINRDIDEVLKYLCENVTWIGPGEQ
                     EFLTSFNEIKNYFYAGQDEIPSCDINNDIFETVSEDENRCMVLGRYTVRTKENTQMIL
                     EVNQRCTFEIIEDRGKLLVKHMHISNPYGEMQLDEYFPTKIGTQSYDYLQRLLKEKTE
                     VIEMITNNINGGLKGSNDDNTYSFFYVNEGLPKILGYTYDEFMEMSGGSAVGAVYPPD
                     LPKALEDCERCFAKGPTYSSEYRIRKKDGTLMWVLDSGMKSLNSDGIVKINSIITDIT
                     QLKNIESELKLERERYRIALQNITDIMFEYDIENDTLIKYQRVEIDKKIELENFETKN
                     YSKLLESGKIIHLDDIGKLLEVLHGNLRETIEIRQVNSLTKNEWRWIRVQCSVIYDSD
                     HNPIKTIGVLKDITEDKSKLESLINQAQRDPLTQLYNQRVSQNLIEEYLCSSDSKNND
                     ALLVIDIDDFKTVNDTFGHLEGNEVLVAVSKILLHNTHDKDIVARIGGDEFTIFIKSL
                     TKDLIIKITNDILNDASKIKVKDNHKITLSIGIAFTDDSTKLYKDLFSKADKALYLSK
                     ADGKNCYSTYE"
     repeat_region   5832..6456
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=5901..5929
                     /rpt_unit_seq="atttacataccacttagttaatataaaac"
     gene            complement(6986..7090)
                     /locus_tag="PC512_003110"
     CDS             complement(6986..7090)
                     /locus_tag="PC512_003110"
                     /inference="COORDINATES: protein motif:HMM:NF024729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HDF2442840.1"
                     /translation="MDDYIYYYNNFRYQNRLNSMSPFEFRKYLSTERA"
     gene            7715..7960
                     /locus_tag="PC512_003111"
     CDS             7715..7960
                     /locus_tag="PC512_003111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442841.1"
                     /translation="MNQKKIKISIKMVIIGIFAVIIAFVLSRLFVEYIDELLRSNWQY
                     QLFESESSYIVFANCIMFSNILLEIFLIYICRKFRKI"
     gene            complement(8713..8859)
                     /locus_tag="PC512_003112"
     CDS             complement(8713..8859)
                     /locus_tag="PC512_003112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442842.1"
                     /translation="MVFETFDKTIELYPNAKPIFHSDIGFRLDDESFEEYLGRVFRKR
                     CKGI"
     gene            8955..9604
                     /locus_tag="PC512_003113"
                     /pseudo
     CDS             8955..9604
                     /locus_tag="PC512_003113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429361.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase family
                     protein"
     gene            10145..11500
                     /locus_tag="PC512_003114"
     CDS             10145..11500
                     /locus_tag="PC512_003114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2442843.1"
                     /translation="MDTKISINENMSLGKRFFKYLAPSVVAMWVFSLYTMVDGIFVSK
                     GVGELALAAVNISMPFINFIFAVSLLFSTGASTIIAIYLGKKDIKSANEVFSFNLVSI
                     IILSIIILAITFFNLDRLALFLGATESTIGMVKDYLGIIIFFNGFFIVSYSLEVIIKT
                     DGFPILATVGVIISALTNIILDYLFVIEFGWGVKGAGIATGLSQVFSTIFFLIHFLRK
                     NSTLNFSKFRIDFKTLRKIVFIGFPDSTTELSCGIVVLLFNLSLTKYIGENALIYYSV
                     INYINTLVLMTMMGITQGMQPLTSFYYGAGNIDNVKKLLKMGIKATIIASVAVFAICM
                     AFSGPIVSLFIHPEETMLFNEGVRVFKIFSISFLLVGINVIISGFFVSVEKPSISTVI
                     SLGRGLVIVVLSLISMILIFGGQGIWMTTIVSEFICLILSLVFLKKNFSTLDSNLNKV
                     A"
     gene            complement(11618..12286)
                     /locus_tag="PC512_003115"
     CDS             complement(11618..12286)
                     /locus_tag="PC512_003115"
                     /EC_number="6.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphthine--ammonia ligase"
                     /protein_id="HDF2442844.1"
                     /translation="MKEVLKLADEKFVMSFSGGKDSILALNRMLKKGYKPVALLTTIS
                     EEHGKSWTHNLEYNMLKQVSSNIGLPLLVAECGVEGYEESFERALIKAKNMGATICAY
                     GDIDIESHRKWDTDRCEAVGMKVDLPLWQESREDLVYEFIDSGFCSVVTKVNLKHLGE
                     EFLGKKLTRELVEKIKNAGADPCGEHGEYHTFVVDGPIFKKPVEYEVKGTLIKDGYGY
                     LEIK"
     gene            complement(12353..12781)
                     /locus_tag="PC512_003116"
     CDS             complement(12353..12781)
                     /locus_tag="PC512_003116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HDF2442845.1"
                     /translation="MTKLWAIIFALLAGGSTALEAFINGELGKSTTALVATFISLTVG
                     AIFFLASIIVTGDLKCLVSINGFNYKLLLGGVFGGLIIYFTVKAIPNLGVSNTLILTL
                     VSQVLVGFFIDSVILGQETMHLYKYIGVILLILGTFFIVN"
     gene            12888..13481
                     /locus_tag="PC512_003117"
     CDS             12888..13481
                     /locus_tag="PC512_003117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HDF2442846.1"
                     /translation="MNFCYNCSIDFGGDFMYTNFNIDFNNFNKKENAIKFMLMGVLLI
                     ILGLLCLTFKTLGIKLISWTFGIALLFFAYLNLKNINELKRYATKEEIKPSINIQWVL
                     IIACILLFVFPQKIQSIFSLFLGFYLIFNQLVALVNSKNNPYSKFTTWNIVKILFGIC
                     LILSPLFLSRFIVSIMSFFIILFGLVLFFSGNTARKY"
     gene            13600..14535
                     /locus_tag="PC512_003118"
     CDS             13600..14535
                     /locus_tag="PC512_003118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893027.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HDF2442847.1"
                     /translation="MDKFKYAFDNKRYHTWNYYLRNTFGEKVFKVSINAGFTCPNIDG
                     SLGYGGCTYCSKEGSGDFAGNPKDNLISQFYNIKEMMLKKWPHAKYIGYFQAYTNTYA
                     PLEVLKEKYETILELEDVIGLSISTRPDCLPDDVVEYLSELNKRTNLWVELGLQTIHD
                     STSKIINRGHDYKTFVEGVEKLKSKNIKVVVHIINGLPGEDYNMMMETAKAVGKMGVD
                     GIKIHLLHVIKDTPMEKMLQNGMLTLMEQDEYINLVCDQLEILPETMIIHRLTGDGKR
                     DELVGPIWSLKKWEILNQIDDTLKARNSYQGCKFV"
     gene            complement(14806..15750)
                     /locus_tag="PC512_003119"
     CDS             complement(14806..15750)
                     /locus_tag="PC512_003119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HDF2442848.1"
                     /translation="MGEKSKGYVFIAIAGLLWATLGLFGKFLMGNGLTSEQVAFTRLF
                     FGFIVLGVYSSIRTPQILKISKKGIIYSVIIGIICQAMFNLCYFKAIDIAGVSIAAVL
                     LYTSPLFLAIFSKICYKENITRSKLFSLILCFIGAIMAVTGGRLDFQGLNAFGLLLGV
                     LSAIAYALMPTISKNALKEFSSSTILVYSFLFGAIFMIPSSRPWEILNYAKDLDVLSC
                     MLMLGIVPAALAYIFYAAGISKGVELSVAGVVASVELVGSVIIGCTILGESFSLGKLF
                     GVMLMLISAVVALNLSYDEIRIFYKSNKLKQIEKTESI"
BASE COUNT         6067 a         2097 c         1992 g         5792 t
ORIGIN      
        1 agttaattat gaataaaata attatgcctt tgaaaaatca ttaaacttaa aattaattat
       61 aaaaaaactc taccttacta actatacagc tcacaatcta tctatttatg aaaaaatatg
      121 atataattgc attcaaaaag gaaatctttc aatatactag aatttaagca ttaactaatt
      181 ttatctaata ttattactaa actaaaaaat atttgtattt gtagcattgg agcaagtaac
      241 ttaatgtata ttcattttaa atacttattt aaaatttagc atttaaatta tttacaaatt
      301 aacatttaaa tacttctagc ataaatacag ttgtcattaa aatttaaagt atcttatgga
      361 ggaataccat gcaaaatcat aattatataa aaatgttaaa taaaaaggta gaagtattat
      421 ctaaggaatt agatagtaga aattttaaat taaaaacctt aaatgaaata gatttttttt
      481 ctaaaatacc aaacagagaa tttatgtacc aacatattga tgactgtatt tcgaaaaata
      541 tacatatagg aatcatgtta ttaaatatcg ataactttaa attatttaat gatatatatg
      601 gatacctagt cggagaaaat ttattaatta ctctaactca aaacctattg cactttattc
      661 cagaatcaaa gggaatagtc gcttatttaa aaggagaagg ttttttaatt gtacttccaa
      721 atgtatcaaa taaagagtta aataatatgg gtgcaactat tatagagagc gcccgagaat
      781 taaaaataaa acttcctaat gaaaaagaaa tatactccaa tgttacattt agtatcggca
      841 gcactatctg gaatggtgaa ccaaacatga ctactttgat gcttttcaac caagtatata
      901 gtgctttaaa aaaggctaaa agtgaaggta aaaatagata cattctattt gattttaaag
      961 ataatagttt ttacaataaa ttagaaaatg ataaggagtt cttatcagaa atatcacatg
     1021 ttctacaaac taaacaaatt gaagtatttt accaaccact ttataatata aaaaataata
     1081 ctatagttgg atgtgaggca cttgcaagat ggagacaccc tattaaagga cttcttactc
     1141 cagataaatt tattccttta tttgaacagt ttggtctgat aacggaatta gatttgcatt
     1201 tatttgaaga gaactgtaaa aatataagaa gatggattga taacaatgat gtttttgttc
     1261 caatttgttg taacttttct cgtcttcatt tttttaaccc taattttcca agtatgctaa
     1321 aaggtattac tgaaaagtac agcgtctcta catcaaattt tagcattgaa ataacagaaa
     1381 atatattaat agaaaataca aatacaatta ttcaacaact agctgaactt cgttcttatg
     1441 gtttttctgt atcaatggac gattttggtt ctggatattc atcttttggt atgttgcaaa
     1501 atctaccttt tgatataatc aaaattgata ggatattttt atctcataat ttaaatgatt
     1561 ttaaaaatac aaccattttg tactctataa taaacattgc aagagctctt gggatgctta
     1621 cagtatgtga aggtgttgaa acagaacaac atgtagaatt tattaaaagt ataaattgtg
     1681 atatcgccca aggttattat tatgcaaaac ccatggagtg caaagaattt gaaaaattac
     1741 tatctaaaga gaataattca gagaaaatgt ttataaaata ttctgatata ggaaaatctt
     1801 taatagagaa gatatttgat ggatttttta ttatgcaaga tatgaaaaaa ctaagagcta
     1861 atgtcactga agacattcaa tggtttgatt tttacaacaa aactgaaatt acatcttttc
     1921 ctaaagtaat agagcatttt gaaaaacata ttaaaggtaa aaaattttct attctttaca
     1981 aaagtataac cccacataat actgaatcag attcattatt aattagtgga gaagccgttt
     2041 tatcagatga agcttctgaa catcaaaaat atagcaattt ctactttagt gcaaattgta
     2101 taatttcaga aaataaatta ctcttagcaa aattacattt ggatttaatt aaaactgctg
     2161 gctatataaa tgaatttgaa tcatattcaa tacctaaaat gacaaataca catcttgatg
     2221 aaagtaatat tttatcacaa ttttattcaa tgttgcctgt aggtataatt cgctacgatt
     2281 tatttggtga tatgattatt acttatatga atgaagaaat gtttgatatt ataggttata
     2341 caaaagaaca gttttttggt gagatgggcg gaaatttaag agcaattgtt catccagatg
     2401 atttagactt tgtttataaa aaaagtttgg atatgattga cacaaataaa attgaaccat
     2461 ttttatatag attcataaaa cgagatggtc aaattgtcac agttatgtat acacaatgta
     2521 acctttctgc aattgatgga aggtcgattg cccagggtat gtatgtagat gtaaataaaa
     2581 taaaaaattt aacaaaaatc tagtacaaag tattttattt tggagaaatt aatatgttta
     2641 aagaaatttt tttaagaact tttccaggat ttctaattat aagagattct aactacagaa
     2701 ttatatttat aaatgataat ttaaaaaatt taattaaaag ttatatgcaa gataatccac
     2761 ttggaatgac taatatagaa atagctaaga aactccctga taatattgct aaatttttta
     2821 cggattctca caatattcaa ttagattggg aaaaaaatta tccttatgat aaaatttcaa
     2881 attggatttt agagtttaaa aaagatacta caagctattg gaatgtttta gaatataaag
     2941 tagatgttga tgaaaaaacc tacataatta ctatggccaa tgatataaca aaactctatg
     3001 aagaaaataa gagaaatctt cactactcaa ttactgaccc attaactgga gcatataata
     3061 gaaaatattt aaatgataga tttgacatat ttataggaga ttatattgta ctaattgact
     3121 tagataattt caaaatgata aatgactatg aaggtcataa tgtaggagac aagattttat
     3181 gtgattttgt ttcactttta aataaagaat taataaattc tacttctatt ataagattag
     3241 gaggagatga atttattgtt atattctcta gtgatgttga caaaaattat gtttattcac
     3301 aactagaagc cttaagagaa aattttttaa aagtattctc taagtataag tatctttcat
     3361 ttagttatgg tgttgataca gtaaaaagaa atttaaaatt gacaatagtt gaattggata
     3421 aaaaaatgta taaaaacaag aaaaaatttg ataaaaatga ttattaatat tgttatttta
     3481 aaataaatta aaattatctt tcttttttta aacttgtaca ttagtttata aatatgtatc
     3541 tatacaagat attgacatta agtactgaag catatattgt ttcagttctt ttttgttaaa
     3601 attaacttat ttaacaaaga tatcatagtt taacaaagct tttaatttaa atatattgat
     3661 gtataatata attaaaatat aatagcaaaa agaaaggagg aatatcatga gcatactcct
     3721 aaaaaaagca cccaaattag caaaacatat tataacaagt ttttatataa atcgggatat
     3781 tgatgaagta ttaaaatacc tttgtgaaaa tgttacatgg atcggaccag gagaacagga
     3841 atttctcact tcttttaatg aaataaaaaa ttatttttat gcaggtcaag atgaaattcc
     3901 ttcttgtgat ataaataatg atatatttga aactgtaagt gaagatgaga atagatgtat
     3961 ggtattagga agatatactg ttcgaactaa agaaaatact caaatgattt tagaggtaaa
     4021 tcaacgttgt acatttgaga taattgagga tagaggaaaa ttattagtaa agcacatgca
     4081 catatcaaac ccttatggtg aaatgcaact tgatgaatac tttcccacta aaattggaac
     4141 tcaaagttat gattatttgc aaagattact aaaggaaaaa acagaagtta ttgaaatgat
     4201 tacaaataat atcaatggtg gcttaaaagg tagcaatgat gataatacat actcattttt
     4261 ctatgtcaat gaaggattgc ccaaaatatt aggatacaca tatgatgagt tcatggaaat
     4321 gagtggtggt tcagcagtgg gtgctgtata tccaccagac ttacctaaag cactagaaga
     4381 ttgtgaacga tgttttgcaa aaggacctac atattcatct gaatatagaa tccgaaaaaa
     4441 agatggaaca ttaatgtggg tattagattc tggaatgaaa tcattaaata gtgatggcat
     4501 agtaaaaatt aatagtatta ttactgacat aacccaacta aaaaacatag aatctgaact
     4561 aaaattagaa agagagcgat atcgtattgc tttgcaaaat attacagata tcatgtttga
     4621 gtatgatatt gaaaacgata cccttataaa atatcaacgt gtagaaattg acaaaaaaat
     4681 tgaattagaa aattttgaaa caaaaaatta ctccaaacta ttagaatctg gtaaaattat
     4741 tcaccttgat gatattggaa aactactaga agtacttcat ggaaatcttc gtgaaacaat
     4801 tgagataaga caagtaaatt cattaactaa aaatgaatgg agatggattc gtgttcaatg
     4861 ttcagttata tatgatagtg accataaccc tatcaaaaca ataggcgttt taaaagacat
     4921 aactgaagat aaatctaaat tagaaagctt aattaatcag gctcaacgtg acccactaac
     4981 acaattatat aatcaaagag tatcacaaaa tcttattgaa gagtatctat gtagttctga
     5041 ttccaaaaat aatgatgctc tattagttat tgatattgat gattttaaaa ctgtaaatga
     5101 tacttttggg catttagagg gaaatgaagt tttagttgct gtatcaaaaa tactattaca
     5161 taacacacat gataaagaca tagttgctcg aattggtgga gatgaattta caatatttat
     5221 aaaatcatta acaaaggatt taataataaa aattactaat gatattttaa atgatgcaag
     5281 taaaataaaa gtaaaggaca atcataaaat aacattaagt attggtattg ccttcactga
     5341 tgattcaact aaattatata aagatttatt ttctaaagct gataaagctc tttatctatc
     5401 aaaagcagat ggcaaaaatt gttatagtac atacgaataa taaagctatt tatacgacca
     5461 agaatgaacc tttaaattta atttcatagt ctaacaatca aagagttgaa gctaatctta
     5521 tagctagtca actagttcct agaaaaaatt taaacaatat atttattgat actgctcatt
     5581 tttctaaaga gcaaatttat ataaaaaatt aaacttttat gtacatacag atactaatga
     5641 taaacagtta tcattagtat cttctatctt aaaacaaaat gataatttat ctatataaaa
     5701 aagtgctttg ttgacagagt tcactttttt atataggtac agaatttaag tataaataca
     5761 tgttttattc tatacatttt agttaatgta aaatttcttg attgtactct ctaacttttc
     5821 aacattatac tatttatata ccacttagtt aatataaacc ccttagctgg ttctagtgct
     5881 ttttctatga ttttagtcat atttacatac cacttagtta atataaaacc aatttagatg
     5941 atgtatatgt gcaaaaggaa gaaataattt acataccact tagttaatat aaaacgctac
     6001 taaacttgat atacatgacc attataataa taaatttaca taccacttag ttaatataaa
     6061 acttccataa aaacatcccc tttttattct tcttccttat atttacatac cacttagtta
     6121 atataaaaca gtcttttttt aatgcagaga tgcaagaagt tttataattt acataccact
     6181 tacttaatat aaaactatca gtatttaagt aataatttaa gtaatatagg atttacatac
     6241 cacttagtta atataaaacg gtcactacaa cttatacttc cagtctaacg atttgaattt
     6301 acataccact tagttaatat aaaacatatt ttggatttat taatataaac ataattaaaa
     6361 aatttacata ccacttagtt aatataaaac tctaaaattg tgttagcata actttttata
     6421 ttttcaaatt tacataccac ttagttaata taaaacccca aaataaactg ggcattttca
     6481 atacttacac atatgcaact ctcttaaatt tgcagtgaac catgagtagt gcaaatgata
     6541 aagcttatca tataccctca acaccttata tttcaagcgt taagctctac tttgtaacaa
     6601 atatcgctca ctgcaaaact atttacattt ttattatatc ataaatatat tatttttgaa
     6661 tatctatacc aatttgtggt ataataaaag caagaagaac tacaatctat ttagacgtag
     6721 agtgaagttc aaatactaat gtttattctt tttgaacttg atttttagtt caaaactaaa
     6781 gtcactcctg cctgtgtgaa ctatacccgc tgttttatac agttaaaaca tgtaaaaata
     6841 gttataaagt actagtgtaa ctcattagta ctctttttat tatattcata taattaatat
     6901 ctatatttta aagtttacta tctaaaaaag agcacgtcaa ataaaaccct agatatttaa
     6961 tttttttaga gatacttaaa ataaattatg ctctctctgt acttaaatat ttcctaaatt
     7021 caaatggaga catagaattt aatctatttt gatatctaaa attattatag tagtatatat
     7081 aatcatctat tgctttaact aattattcat atgtatcaaa tttccttaaa tagtacattt
     7141 ctacctttaa aattccccaa aatccttcca taggagcatt gtcaaggcaa cgaccaactc
     7201 ttgtataata tatgtatatc taacaccatt aagaaatata tattttataa tatatatttc
     7261 ttcatttaat gcacttagaa aagcaaagaa aatacagatt agtacacttt ttagagaaaa
     7321 ataaaattaa tacatctaaa atattaaaaa atactttaga taatctaaag acacatctca
     7381 aagtttttaa ctaaattata aaactaatta caaatgctat gtaacgataa taaataaaaa
     7441 atttacttcg cttaagcgac gtgtcgttga aatatttcat gttgccaact ggttcgtaag
     7501 ttgataagaa aagaacacta attatttaga gttcttttct tagctacaag tggattataa
     7561 tacttttaaa tctgtgagaa aatcatatat aataatgata tgaacaagta aagaaaatac
     7621 aaaaatgaca aaattataaa taaaatatta taaaatcata aggtcataat tgttatattg
     7681 tagaaacaaa gtaaagagag agggtggaga ataaatgaat caaaaaaaaa taaagattag
     7741 tattaaaatg gtaattatag gtatatttgc tgtaattatt gcttttgtat tatccagatt
     7801 attcgttgag tatattgatg aattattaag gtctaattgg caatatcagc tatttgaaag
     7861 tgagagttca tatatagtat ttgccaattg tattatgttc tcgaatatat tattagaaat
     7921 atttttaata tatatttgta gaaaatttag aaaaatctaa tatggtcaac gtatttcgaa
     7981 tcgaatactt catgattatt tagtctattg tgctagttaa agtttaattc ccatataaag
     8041 taaattgatt ttagtaaaac aaatcacccc taagggttag tttatggata agtcatccaa
     8101 atattaactc tttaattttt gctatagatt catctttgct cataacttta cttataaaaa
     8161 atgaaatatt ataagctaga acttttattc taattctagt cataaatcct agcatagagt
     8221 tacttttttt atattataaa taaaactata caacaaagat aatatttagt aaaaataact
     8281 ttcattttaa ctaaacttaa aattcaatta ctctctaaat tgacgtttag gaattagttc
     8341 aaaataaaaa agagtgtata tattgaaatt actacatttc aatatataca ctctttttaa
     8401 atttctcagt tttccatgga actttacttt atttatttct gtattagttg tattttttat
     8461 gcatttttct ttaaaatcat attttctgat tcaactctta tattataaaa tttctttact
     8521 aaattattct ctttttctat atcttcatat atatttttta atcgcctttt acctaatctt
     8581 ttatctaaca ttactaatga tttaactaat atattatatg attttatcgc atcttctatt
     8641 gagatattta aacatatatt tactgcttca taaaaatcaa attcattaaa aaatccattt
     8701 ttatttacaa tcttatatcc ctttgcatct ctttctaaat actcttccta aatactcttc
     8761 aaaactttca tcatctaatc taaatcctat atcactatga aaaataggtt ttgcatttgg
     8821 atatagttct attgttttat caaaagtttc gaataccaag ttattattat tcgattttcc
     8881 aacagtccac tataaacaat aataagtttg ttgctccaaa taatgtaaca cttgtagaaa
     8941 gatgttacag atatataaaa gatagagaat gtagtttttc tcctaatact attagaaata
     9001 gaaaaaatat gattaaaaat caaattgaag ttttctttaa agatatgaaa ttaatagata
     9061 taactccttc tattttacag tcttatataa ataacatata caatgagcac atgttaaatt
     9121 caacaaaaaa ccaagtcgat tttataaaat cagtattgaa agaatcttat agattaaaag
     9181 aaatatcaga aaatatttgt gattttgtta caaccccaat caaaaaaaat agttcaactt
     9241 ctaagcttta tacaaaacaa aaagctcaat tattattaga aaaatcaaaa aatattccta
     9301 taggtatacc aatttttttg atgctaactc ttggattacg ttttggtgaa gctgtatcac
     9361 ttatatggtc agatgtagac cttgataaaa aatctcacat gtaaatcaaa cattagttta
     9421 tgtatacaat aaaataatct tcaaaggccc taaaacccct agattcaaaa gaagattatt
     9481 tgttcctgat gaacttataa gtttgtttaa aggggaaaaa ttaaaacaaa ataagttaaa
     9541 attacagggt atattgaaaa atgaatttga tttgatatgc ttaaataaaa gattcaaccc
     9601 gtgagttcaa ccaacttttg ttgttcattt taaaaaacta ttaagagata ataatcctag
     9661 agatataaaa gtacatgaat taatacatgc aaatgcgact ttgatattac tttcaggtac
     9721 taacataaaa gctatttata aaatattagt acatgcagat ataaaaatag ctatgaatat
     9781 atattccata ttctcactta ttagatgaaa tgaataaaga aacatctgaa aatataagca
     9841 aaatactatt caaataatgt tcagttttat gtcaattaaa tgtcactcaa agtgcttttt
     9901 ttccatttgt cagttaaatg tcacttaaag tacctttttc ctatttgtca gttaaatgtc
     9961 agtaatatat aaataagata tatttataag acccttaaaa tcactattat ttaataaaat
    10021 ttataattat atactatttg ctgttgacat tggtattata ccatagttta tcatttatat
    10081 tagaataaaa ttattaatta atagtttcgt aattttataa tagatttaca gggagtgata
    10141 ataaatggat acaaaaatat ctataaacga aaacatgagt ctaggtaaaa gattttttaa
    10201 atacctagca ccatctgtag ttgcaatgtg ggttttctca ctatatacaa tggttgatgg
    10261 aatatttgta agtaaaggag ttggagaatt agctttagct gctgtcaata tatcaatgcc
    10321 ttttattaat tttatatttg cagtttctct attattttca actggtgcat ctaccataat
    10381 tgcaatctat ctggggaaaa aagatattaa atctgctaac gaagtctttt catttaactt
    10441 agtatcaata attatattat caataattat attagctata acttttttta atttagatag
    10501 attagcacta tttttaggag ctacagaatc tacaattggt atggttaaag attatttagg
    10561 aataataata ttttttaacg gattctttat agtgtcttat tctttagaag ttataataaa
    10621 aactgatggc tttccaatat tagctactgt tggtgtaata atatctgctc ttacaaacat
    10681 catacttgat tacttgtttg taattgaatt tggatggggt gtaaaaggtg ctggtattgc
    10741 aactggtttg tctcaagtct tttctactat tttcttctta atacattttt taagaaaaaa
    10801 ctctactttg aatttttcaa aatttagaat tgattttaag acacttagaa aaattgtatt
    10861 tataggtttt cctgattcaa ctactgaatt aagttgtggt atagttgttt tactttttaa
    10921 cttaagtctt actaaatata ttggagaaaa tgctcttatt tattatagtg tcataaatta
    10981 tataaataca ttagtactta tgactatgat gggtataact caaggtatgc aaccacttac
    11041 tagcttttat tatggtgcag gaaatataga taatgtaaaa aaattattaa aaatggggat
    11101 aaaagccaca ataatagcat cagttgctgt atttgcaatt tgtatggctt tttcaggacc
    11161 aatagtctct ttatttatac atccagaaga aacaatgcta ttcaatgaag gagttcgtgt
    11221 atttaaaata ttctctatat ctttcttatt ggtaggaatt aatgtaataa tttctggatt
    11281 ctttgtatca gtagaaaaac catcaatttc tactgttata tctcttggta gagggcttgt
    11341 aatagttgtt ttaagtctaa tttcaatgat actaatattt ggtggacaag gaatatggat
    11401 gactactatt gtttctgagt ttatatgtct tattttatca ttagtttttc taaaaaagaa
    11461 tttttctaca ttagactcta atctaaataa ggttgcttag atgataagag tgacaatata
    11521 tgaaaatatc taaataaaaa atacctatta tacaatcttg caaatattaa acctttgcaa
    11581 aaattaggat tatataatag gtattttatt tatgtaatta ttttatttct aaatatccat
    11641 agccatcttt tattaaagtt ccttttactt catattctac aggtttttta aatattggac
    11701 catctacgac aaatgtatga tactctccat gttctccaca tgggtctgca ccagcatttt
    11761 ttatcttctc cacaagttct ctagttaatt tttttcctaa aaattcctct cctaagtgct
    11821 ttaagtttac ttttgttaca acactacaaa atccactgtc tataaattca tatactaaat
    11881 cctctctact ctcttgccat aatggtaaat ctactttcat accaactgct tcacatctat
    11941 cagtatccca ttttctatga ctttctatat ctatatctcc atatgcacat atcgttgctc
    12001 ccatgttttt agcttttatt aaagccctct caaagctctc ttcatatcct tctacgccac
    12061 actcagcaac taataaaggt aatcctatgt tgctacttac ttgcttaagc atattatatt
    12121 ctaaattatg tgtccatgac tttccatgtt cttcacttat agttgtcaag agtgccacag
    12181 gcttatatcc ttttttcaac attcgattta atgctaatat actatcctta ccaccactaa
    12241 atgacattac aaatttttca tcagccaatt ttaacacctc tttcatctaa ctttgtttta
    12301 ttaacataat tataccaaat ttttgagttg catagcaaat tatattaaat tgttaattca
    12361 ctataaagaa tgtccctaat attaaaagta taacccctat gtatttgtat aaatgcattg
    12421 tttcttgtcc caaaattacg ctatcaataa aaaatccaac taaaacttgg gatacaagag
    12481 ttaatataag tgtatttgat actcctaaat ttggaattgc ctttactgta aaatatatta
    12541 ttagacctcc aaatactcct cctaataaca acttataatt aaaaccattt atagatacta
    12601 gacactttaa gtcacctgta actattatac ttgccaaaaa aaatattgct cctacagtta
    12661 agcttataaa ggtggccact aatgctgttg tactttttcc tagctctcca tttataaaag
    12721 cttcaagagc tgtagaacca cctgctaata atgcaaatat tattgcccat aattttgtca
    12781 tggacaaacc tccttctata taattctatt aatagaagtt tatgatacaa cctattaatt
    12841 aattactaag tatagtttaa tttttataca ctaggcttta tttggatatg aatttctgtt
    12901 ataattgttc tatcgatttt ggaggtgatt ttatgtacac aaattttaat atcgatttta
    12961 ataactttaa taaaaaagaa aatgctatta aatttatgtt aatgggagta ttactcatta
    13021 tattaggatt attatgcctt acatttaaga cattaggtat aaaattaatt tcttggactt
    13081 ttggtattgc acttttattc tttgcatatt taaatttaaa aaatattaat gagttaaaaa
    13141 gatatgctac taaagaagaa attaaaccct ctattaatat ccaatgggtt ctaataattg
    13201 catgtatatt actttttgta tttcctcaaa aaatacaaag catattttca ttatttttag
    13261 gattttattt aatctttaat caactagtag cacttgtaaa tagtaagaat aatccttatt
    13321 ctaaatttac aacttggaat atagttaaga ttctatttgg tatatgcctt atattatctc
    13381 cacttttttt atctagattt atagtatcga taatgtcttt tttcataata ttatttggac
    13441 tagttctatt tttctctgga aatacagcga gaaaatatta attattttct cgctgtattt
    13501 ttatattact taaaatagaa tttgtttaag ttatctattt gtggtaatat gttttttgta
    13561 caagctcagc gtacaatttt attagaaata ggtgattttt tggataaatt taaatatgct
    13621 tttgataata aaagatatca tacttggaat tactatctta gaaatacttt tggagaaaaa
    13681 gtttttaagg tatctataaa tgcaggattt acttgcccaa acattgatgg aagtcttggt
    13741 tatggcggat gtacctattg tagcaaagaa ggctcaggtg attttgctgg aaaccctaaa
    13801 gataatctta tcagtcaatt ttataatata aaagaaatga tgttaaaaaa atggcctcat
    13861 gcaaagtata ttggctactt tcaagcctat acaaatacgt atgctcctct tgaagtttta
    13921 aaagaaaaat atgagactat attagaactt gaagatgtca taggtctttc aatatccaca
    13981 agacctgact gtttgccaga tgatgttgta gaatacttat ctgaactaaa taaaagaacc
    14041 aatttatggg ttgaacttgg acttcaaaca attcatgatt ctacatctaa aattataaat
    14101 agaggtcatg attataaaac atttgttgaa ggtgttgaaa aactaaagtc taaaaatata
    14161 aaggttgtcg tacacattat aaatggtctt cctggtgaag attataatat gatgatggaa
    14221 acagcaaagg cagttggtaa aatgggtgta gacggtataa aaatccatct attgcatgtt
    14281 ataaaagata ctcctatgga aaagatgtta caaaatggta tgttaactct tatggaacaa
    14341 gatgaatata tcaatcttgt ctgtgaccaa ttagaaatac ttcctgaaac tatgataatc
    14401 catagactca ctggtgatgg taagagggat gaactagtag gtcctatatg gagcctaaaa
    14461 aaatgggaaa ttttaaatca aattgatgat actttaaagg ctagaaattc ttatcagggc
    14521 tgtaagtttg tttaatacaa aataataact atagaaatgg ttatataaat atagtccttt
    14581 ctatagttat ttagtattta caaaacaaaa tattaatttg tacatttata caatatataa
    14641 taaaaaatag atagtctaaa ctgtatctac ttatatttta tttgtactgt ccactttatt
    14701 ctataaaatt tataaatagt tattttttaa taccaaatat aatttggtat aatttttgtt
    14761 ggactctaaa atgtatacca ataaatcctt tttaagtata taattctaaa tactttcagt
    14821 tttttcaatc tgctttaact tgttggactt ataaaatatt cttatttcat cataagaaag
    14881 attaagtgct actactgcag atattaacat caacatcact ccaaataact tccctaagga
    14941 aaaactttct cctaatatag tgcaaccaat tattactgaa ccaactaatt ctactgatgc
    15001 cacaacacct gcaactgaca actctacacc tttagatata cctgctgcat aaaaaatata
    15061 tgcaagtgca gctggaacaa tgcctaacat tagcatacaa gataaaacat ctaaatcctt
    15121 agcataattt aagatttccc aaggtcttga agaaggaatc ataaatatag ctccaaataa
    15181 gaaactgtat actaatattg ttgaacttga aaattccttt aaagcatttt tactaatagt
    15241 tggcataagt gcatatgcta ttgctgataa taccccaagt aaaagtccaa aagcgtttaa
    15301 accttgaaaa tccaaacgtc caccagtcac tgccataatt gcaccaataa aacaaagaat
    15361 aagtgaaaat aatttgcttc tagtaatatt ttctttataa catatttttg aaaatattgc
    15421 taaaaacagt ggtgatgtat atagtaaaac tgctgcaatt gatacacccg caatgtcaat
    15481 tgctttaaaa taacataaat taaacattgc ctgacatata atacctatta ttactgaata
    15541 tataattcct tttttgctta tctttaagat ttgtggtgtc cttatagatg aatatacgcc
    15601 taaaactata aatccaaaaa acaatcttgt aaatgctact tgttctgatg tcagtccatt
    15661 tcccattaaa aactttccaa ataatccaag tgtagcccat aataaccctg ctattgctat
    15721 aaatacatac cctttacttt tttctcccat tttaaattcc cttctatttt tatttagtca
    15781 atttacactc ttctttttaa gcaaaaacta tgccatctta aatcaatata tatcgactct
    15841 aaaaccctag tctttccaat aatactaata aattttcaat ttttttatat ttatttttca
    15901 cttactttaa gttgatttag acttatttta attgtaaaat gagttata
//
LOCUS       DAMJVG010000090        15207 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.092, whole genome shotgun sequence.
ACCESSION   DAMJVG010000090 DAMJVG010000000
VERSION     DAMJVG010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15207)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15207)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15207
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.092"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            59..1489
                     /locus_tag="PC512_003120"
     CDS             59..1489
                     /locus_tag="PC512_003120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2442849.1"
                     /translation="MNLDLEFYQKILEASHDEICVSDDKGIIIYCNKAFEENYGLKKE
                     DILGKNVSFLEDSGYSTKSPIPIVLKTKTKFSLEQDTQTGKKLIITATPIFDENGNLE
                     FTVENCRDITELNNIKNKLEDTKKQVKKYKSEVETLYRTALRIEDTVIMDGIVMRPII
                     NTVNHVSKTDVSVLLLGESGTGKSSLARYIHHNSNRSNGPFITINCATISPQLLESEL
                     FGYTSGAFTGASTKGKVGLVELANGGTLFLDEIGDIPQNLQAKFLQLIQDRTFTPVGS
                     LKNKKVDIRIISATNVDLVSKVKEKKFREDLYYRLNVIEIKLPPLRERRDNLVEIIKY
                     YFNRYSSDFNLNKTISKEAMDAIANYRFPGNIRELQNIIQKILLTCTDNHITIDDLPN
                     ILTKNIHITNNGNKTHISQINKVIISDSKSTNYKNKNFDTLIKEYEKNIILDAYEKFG
                     SSYKVAKHLEISQSKANRLIRKYTNT"
     gene            1689..2273
                     /locus_tag="PC512_003121"
     CDS             1689..2273
                     /locus_tag="PC512_003121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc dependent phospholipase C family protein"
                     /protein_id="HDF2442850.1"
                     /translation="MLMNTHFIMAKSILDNIDENKTFFISEKNFIYGNIKPDAFSKYK
                     LKKHYLDESFNMIVSKINYLCSLNIDSLSKYFSVSRLSQELGVICHFLCDFFCVAHSE
                     RWEFKHSLNKHVTYERELGAFAKDVDLSKIKCGTINSSFEKFFTKLYSDYKKKTDYMN
                     DLKFSAYTCNSVINYILDSILSNTIKSYHIANCG"
     gene            complement(2377..3156)
                     /locus_tag="PC512_003122"
     CDS             complement(2377..3156)
                     /locus_tag="PC512_003122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDF2442851.1"
                     /translation="MIKHIFCDLDGTLYENGTITKEDIVAIEEIEKKGVQFNVATGRI
                     FKQAHNIIKDSLDMNGYYVCENGSFIYDKDYNVIFKRTIDDNLVKKVIDRFESSDAQL
                     YFKYKGDVIVGSDTTAFRHYSSDFIVDPDFEKRSSFDNLIGNIGVCSENLEELSRIEL
                     YLKSEFSEVLEIYFSGTYTLNIVPKSVSKRGSIEHVIKTLNVSPDEVATIGDSPNDIC
                     MLEGFKYSFAMSKAREDVKQSANYVVDSVKSAIDVIMEINS"
     gene            complement(3214..4470)
                     /locus_tag="PC512_003123"
     CDS             complement(3214..4470)
                     /locus_tag="PC512_003123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011591286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HDF2442852.1"
                     /translation="MKAEIISVGTEILLGDIVNTNSQFLAKELASLGIEVYHQSTVGD
                     NKQRLLECFDESLKRSDFVITTGGLGPTGDDMTKETAAEYFGQKLELHKPSLEVLESF
                     FVKTGKKMAENNMKQVYFPKDAIVLKNNNGTAPGAILKKDGKFIIVLPGPPREMKAMF
                     NESVKPYLQQFTNEMLVSKTLRLYGIGESNLELEILDIINEQTNPTVALYAKELEVTI
                     RITAKAENEREAFKLIKPVEEKIKSRVGKYVYTEGDISISEGETALEDAVSKLLVEKN
                     LTIAVAESCTGGLVSSSLINYPGISSVFLEGCVTYSNDSKMKRLGVKRETLEEFGAVS
                     EQTAIEMAEGVAKGLKANIGISTTGVAGPGGGTKEKPVGLVYTAIYINGKTIVKKNIF
                     NGDRRKIRLRATRDLLNELRIQLEKL"
     gene            4728..5627
                     /locus_tag="PC512_003124"
     CDS             4728..5627
                     /locus_tag="PC512_003124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HDF2442853.1"
                     /translation="MKIAVIMGGISSEREVSLNSGKEIYNNLDKNKYEVVKVIIDDKK
                     DIFTKIPEDIDFAILALHGKFGEDGCIQSILETMDIPYSGCGPLCSGMCMDKNITKKM
                     LRDSNLPTAPWVLVKSVDEIDYDEIDNIGYPVFIKPNSGGSSVATFFIHSKDEVEEAV
                     RKGLEVDEFVMIEKYIPGGEYTSFILNGEVFPTISIKSDSGFFDYEAKYSVEKGAKEE
                     VVYLDEELQKRVNEISETCWKIFNCKAYVRVDMIISEGIPYVLELNTLPGMTQTSLIP
                     RSAAARGIKYSELLDKLIEYSLN"
     gene            5651..7099
                     /gene="ddlR"
                     /locus_tag="PC512_003125"
     CDS             5651..7099
                     /gene="ddlR"
                     /locus_tag="PC512_003125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator DdlR"
                     /protein_id="HDF2442854.1"
                     /translation="MIFSNLKLNDNEPIYIQLKNYISDMISKGLIPDNSKLPSTRELS
                     QLLQVSRNSVVLTYEELKSEGLIYSISGKGTFVKSKNKSSNTTWSLNWDCLENTYSKK
                     ANELDIIKSEIPWSSDLISFKSISPDGDLFDIEELKKSFLNRISLEGHKLLNYGYAQG
                     YKPLIDYLLEYMTNKGADISNKDILITNGFTEGFDIIMSSFTQEKDYIICENPTHNTA
                     IKIMKSHNLNILGVDINEDGLDFNMLEDNLVKYKNKIKFAYITPSYHNPTGIVMTPEN
                     RYKFYNLMKKYNIAIIEDGFNEELLYNSSHIFPICSLDNMNNGVVYIGSFSKILFPGM
                     RIGWIFADKKVINKLESVKRCRNIHVSFLDQGILFDYLSNGGFEKYIKKIRKFYGDKF
                     NFAYKCIKKYIKTEYILGDGGLHIFIKLKNIDTRVLLEKCYEKNVIFMPGDLFFTDNS
                     GFDTLRLGFSRLSFEDIEIGIKIIGETINEMF"
     gene            7158..7964
                     /locus_tag="PC512_003126"
     CDS             7158..7964
                     /locus_tag="PC512_003126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HDF2442855.1"
                     /translation="MNLILGDNMSKKSKRRKINKLKLTIVITVLFLALLSIYEILFSN
                     PNKKGNIKSQETMQNKNNTTDDSKNNQSSTKKQEDNNIKPTFSYSSIPDNIKNKMIGK
                     SMPTDEPISFDSLSYLKLTYYGFDEKTHQGEMIVNSELAPEVVDIFKELYEKKYPIEK
                     IKLIDDYDAVDEKSMSDNNTSSFCYRTIAGTNVVSNHGKGRAIDINPLQNPQVSGNDV
                     TPKVSTVYADRSSTKFGMIKKGDDCYNAFVSRGWSWGGYWKNPDYQHFEK"
     gene            7990..9909
                     /locus_tag="PC512_003127"
     CDS             7990..9909
                     /locus_tag="PC512_003127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_071223118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDF2442856.1"
                     /translation="MNLMTLENISKSYSEKKLLENISLGINEGEKIGLIGVNGTGKST
                     LLKIIAGVEESETGNITKTNGIRIEYLPQNPTYNENSTVLEQVFNGTSEELKLLGEYQ
                     EILEKLNSNFTEELNKKLLSVHEKIDALNLWDLESEAKSVLTKLGINDFNQKIAELSG
                     GQRKRVSLASALITPCEFLILDEPTNHLDNDTIDWLEEYLNSRKGSLLMITHDRYFLD
                     RVTNRIIELDKGRLFSYDGNYSIFLEKKMERLSLEASIEDKRQNLIRTELAWVRRGAQ
                     ARSTKQKARLQRFDELINRDSFKPDENLDISVASSRLGNKIIEIHNISKSFEENTVID
                     NLEYTLTRTDRIGIIGKNGMGKSTLINILNGEIEPDSGYISIGETVKIGCFSQDDSHM
                     NIDMRAIDYVKEASDYIETSDGTRITASQMCERFLFNGTMQYTLIGKLSGGERRRLHL
                     LKILMTAPNVLLLDEPTNDLDIETLKILEEYLDEFKGVVVTVSHDRYFLDRICNKIFA
                     YEGNGKIHIYTGNYSDYLIYREIQGIEFEESKKESVKKDDSTTLKKEKPKNDKKLKFS
                     YNEQREFENIDSDIEKLESKIATLDESTAKFSTDFTKLQEILDEKSKLEKELEYKYER
                     WEYLNNLADEIANNK"
     gene            complement(10151..10498)
                     /locus_tag="PC512_003128"
     CDS             complement(10151..10498)
                     /locus_tag="PC512_003128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PqqD family protein"
                     /protein_id="HDF2442857.1"
                     /translation="MSKSNDVLDIVFKITDGLEYEVAENRVVTILEKQDHKIQKFFRK
                     LKARIPKYKKIELDEYSSFVFLQIDGQRTVREIGKNLEAKYGEESHPLYERLLVFLNH
                     IEVNCHYIERLDI"
     gene            complement(10485..12413)
                     /locus_tag="PC512_003129"
     CDS             complement(10485..12413)
                     /locus_tag="PC512_003129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide transporter, OPT family"
                     /protein_id="HDF2442858.1"
                     /translation="MNKKLPKGAYGEVSGKDYVPYITDKSRTGGNVAVLIIGIILAAI
                     FAASTTYSGMKAGLTVAAGIPGAIIGSAFVGAFARSKGILGKNLIQGMSSGGESVASG
                     FIFVLPAVILIGSQITFFEGLAVGVGGVLFGIGIAAIVHNYLIVEEHGKLMYPESMAI
                     SETLVASEAGGDSIKYMGIGFVISGFITVLTGSFLNVANNVMSLVGSKFYKWKFDIEV
                     NPLLLGIGFIVGLEVSLTMFAGSILSNFGIAPLIGYFTDMAKDGAMVWNNPAMPLNQM
                     DVGAISSSYVKYIGAGMMLCGGIIGAIKLIPTIIASIKETLKAKSSAGEGEEGSSIQM
                     ILLLGGVVIGFLAAFLISGNIVMAIIGAIISLLLSLLFVIVAGRLTGTIGTSNLPVSG
                     MTIASLVIVTLVFVIMGWTDLEANKSLLLFGSFIVVAIAIAGGYTQSQKVTYIIGGSK
                     NEMQRYFTIASIVGVIVVVGVILLLSDQLRATGDNVQFALPQANLMSTLTSGIMSGSL
                     PWVMIIVGVFMAIVLYALNLPIMTIAIGFYLPIATTSIILVGALIRLFVELVSKTEKE
                     KEVKVSNGISLSSGLVAGGSIIGLIGIILQVTGVVTPKVPSGFAATNSMAIALLVVLV
                     VLTALPIVLSKVKNNEQE"
     gene            complement(12824..15013)
                     /locus_tag="PC512_003130"
     CDS             complement(12824..15013)
                     /locus_tag="PC512_003130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid adenylation domain-containing
                     protein"
                     /protein_id="HDF2442859.1"
                     /translation="MYEVNLERAMNYWMDLLDDYTNIAKIPNDFFYKDCSDEVVDEVF
                     KMNIEKHERLIQYSKVNNISIDSIIETIYGLILQKYIYEDDVVFGKTMNIIPIRVRVR
                     QSEKFIDVVRKLKRQWSRSLEYGYYLLSDIENKNHLNTKLINTIFIAKSFDLSYDYDI
                     EKKGYDLSVIVYTKRALKIKIKYKPSIYKRETIRRILNQFDYIIEQIIEDNDILIEDL
                     EFVCKEEEKVLLEDFNNNQYEIPYDKSYVDLFREQVKVTPSNIAARDENRKLTYKELD
                     EVTDKLAGYLNHIGVESEDIVAVMLPRDINIIITAIGIMKSGGAFFPIDTSNPEERLN
                     YLLEDSNAKVVITTDELKSKVVNENTIVLDINDEEMFKLGYELTEKITSSNCAYTIST
                     SGSTGRPKTIAIEHKSLVNMCYYSVKSISATENDICGIYLSFSFDAVMKQLFPYLLVG
                     ASIDIMPEEAKFDEYTVNEYCEENDITILALPTAFARLFIQNCNNNSLRVVQTGGERL
                     KGYRKRNYELYNEYGPTEFTVVSTSFHVDREYGKIPIGKPIFNTYAYVLDKKNKLCPI
                     GAPGELCLSGIQISRGYLNKKGLTEQVFVENPYKTCEHNKLMYRTGDLVRWLDDGNLD
                     YIGRMDNQVKIDEFRIELYEIENIINNITEIKSVVCISRTNDDGDMYICAYYVIDEED
                     SGKINERTIREYLNEHLPPYMIPTIIMRIDKIPVTPIGKVNKRALPE"
BASE COUNT         5629 a         2287 c         1968 g         5323 t
ORIGIN      
        1 attaatcaat taaacctatt ttaatatatc attaaaaatt taggaggaaa atataaaaat
       61 gaatttagat ttggaatttt atcaaaaaat attagaagct tcccatgatg aaatatgtgt
      121 ttctgatgat aaaggaataa taatatattg taataaagca tttgaagaaa attatggtct
      181 aaaaaaagaa gatattttag gaaaaaatgt ttctttttta gaagactctg gatattcaac
      241 aaaaagcccc ataccaattg tattaaaaac aaagactaaa ttttcactgg aacaagatac
      301 tcaaacaggg aaaaagctta tcataactgc tacccctata tttgatgaaa atggaaactt
      361 agaatttact gttgaaaatt gtagagatat aactgaactt aataatataa aaaataaact
      421 tgaagacaca aaaaagcaag taaaaaaata taaatctgaa gtagaaacac tatacagaac
      481 tgcacttaga attgaggata ctgtaattat ggacggaata gttatgagac caatcataaa
      541 cacagtaaat catgtttcta aaacggatgt aagtgtactt ttattgggtg aatctggaac
      601 aggaaaaagc tcacttgcta gatatataca ccacaacagc aatagatcta atggcccatt
      661 tataacaata aattgtgcaa ctatatctcc acaacttctt gaatctgaac tttttggata
      721 tacttcaggt gcttttacag gtgcaagtac taaaggtaaa gttgggctcg tagaattagc
      781 taatggagga actctttttt tagatgaaat aggagatata ccacaaaatc tacaggcaaa
      841 atttttgcaa ttaatacagg atagaacttt tactccagtt gggagcttaa aaaataaaaa
      901 ggtcgatata agaattatat ctgctacaaa tgttgattta gtttcaaaag taaaagaaaa
      961 aaagtttaga gaagatttat actatagatt aaatgttata gaaataaaat tgcctcctct
     1021 tagagaaaga agggataatc tagtggaaat tataaaatat tattttaata ggtactcaag
     1081 tgacttcaat ctaaataaaa ctatttctaa agaagctatg gatgctattg caaattatag
     1141 attcccaggc aatataagag aattacaaaa tataattcaa aaaatcttgc ttacttgtac
     1201 agataatcat ataacaatag atgacttacc aaacattctt acaaaaaata tacatattac
     1261 caataatgga aataaaacac atatatccca aattaataag gttattatat ctgactcaaa
     1321 atctactaat tataaaaata aaaattttga cactttaatt aaagagtatg aaaaaaatat
     1381 aattttggat gcttatgaaa aatttggtag ttcttataaa gtagccaaac accttgaaat
     1441 ctcacagtct aaagccaata ggttaattag aaagtatact aatacttaat tttaaatttg
     1501 ataaataaaa acttaacact atttacatat tgtaaatttg gccatttact gttattatga
     1561 atatggttga aattatttaa ataaatactg ttgacttagt ttcatatatt taccattaaa
     1621 cttttatcat aaatatcata tcataataat atatttaata agtctaataa actatacgag
     1681 gtgtaaatat gttaatgaat acccatttta ttatggcaaa atcaatactt gataatatag
     1741 atgaaaataa aacattcttt ataagcgaaa aaaattttat atatggcaat ataaagcctg
     1801 atgctttttc taaatataaa ttaaaaaaac attatttaga tgagtcattt aatatgattg
     1861 tttctaaaat aaactatcta tgcagtctta atatagatag tctttctaaa tacttttcag
     1921 taagtagact tagtcaggaa ctaggagtca tatgtcattt tttatgtgat tttttctgtg
     1981 tagctcacag tgaacgttgg gagtttaagc atagcttaaa taaacatgtt acttatgaaa
     2041 gagaacttgg agcatttgca aaagatgttg atttatctaa aattaaatgt ggtactataa
     2101 atagtagttt tgagaagttt tttactaaac tttatagcga ttacaaaaag aaaactgatt
     2161 atatgaatga tttaaaattt tcagcttata cttgtaatag tgtcataaat tatatacttg
     2221 actctatttt atctaataca ataaaatcat atcatatagc aaattgcggt taacttaaga
     2281 atttttaaac ttatataaac ttataattga atataattaa aatgactgct ctatagaata
     2341 taattttata cttctctagg acagtcattt tttatactaa ctatttatct ccattataac
     2401 atctatggca ctttttacac tatctactac ataatttgca ctttgcttta catcttccct
     2461 tgccttagac attgcaaaac tatatttaaa tccttctaac atgcaaatat catttggaga
     2521 atccccaata gtagcaactt catctggact tacatttaac gtttttatta catgctctat
     2581 acttcctctt tttgacacac ttttaggaac tatatttaaa gtatatgttc cagaaaaata
     2641 tatttctaag acttcactaa actcactttt tagataaagt tctattctgg ataactcttc
     2701 caaattttca gaacatacgc ctatatttcc tataagatta tcaaaactac ttcttttttc
     2761 aaagtctggg tcaactataa agtcactaga ataatgtcta aaagcagtgg tatcactacc
     2821 cacaattaca tcacccttat atttaaaata aagttgtgca tcacttgact caaatctatc
     2881 aatgactttt tttactaaat tatcatctat cgttctttta aaaattacat tataatcttt
     2941 atcatatata aatgaaccat tttcacatac atagtatcca ttcatatcta aactatcttt
     3001 gataatatta tgtgcttgtt taaaaattct acctgtagca acattaaact gtactccctt
     3061 tttttctatt tcttcaattg ctactatatc ttcttttgtt atggttccat tttcatatag
     3121 agttccatct aaatcacaaa atatatgttt tatcataaat taaaagcctc caaaaacaat
     3181 tttatatttt actaatactt taatcaaaat aacttaaagc ttttctaatt gtattctcaa
     3241 ctcattaagc aaatctctag tagctcttaa tcttatcttt cttctatccc cattaaatat
     3301 atttttcttt actattgttt ttccatttat atatattgca gtataaacca gtcccacagg
     3361 cttctctttg gttcctccac caggtccagc tactccagtt gtagatatac ctatattagc
     3421 tttaagtcct ttagcaacgc cctcagccat ttctatagct gtttgctcac ttactgctcc
     3481 aaactcttcc aaagtttctc tttttactcc taatcttttc attttagaat cattagaata
     3541 tgttacacaa ccttcaagaa atacagagga tatacctgga tagtttataa gagatgaaga
     3601 aaccaaacct ccagtacaag attcagccac tgctattgtt agattttttt ctacaagtag
     3661 cttagaaaca gcatcttcta aagcagtctc cccttcagat atggaaatat ctccttcagt
     3721 atatacatat ttaccaactc tactttttat tttttcttct actggtttta ttaatttaaa
     3781 agcttctctt tcattttcag cctttgcagt tattcttatt gtaacttcta attcttttgc
     3841 atataaagca actgttggat tagtctgctc attaattata tcgagaattt ctaattctag
     3901 atttgactca cctattccat ataatcttaa agtcttagat actagcattt catttgtgaa
     3961 ttgttgtaag taaggtttga cactctcatt aaacatagct ttcatttctc ttggaggtcc
     4021 aggcaatact attataaatt taccatcttt ttttaaaatt gcccctggag ctgtaccatt
     4081 attatttttt agtactatag catcttttgg aaagtacact tgtttcatat tattttcggc
     4141 catttttttc cctgttttaa caaagaaaga ttccaaaacc tctagtgaag gtttatgtag
     4201 ttctaatttc tgaccaaagt attctgcagc agtttctttt gtcatatcat caccagttgg
     4261 cccaagacca cctgtagtaa ttacaaaatc acttctcttt aagctttcat caaaacattc
     4321 taaaagtctt tgtttgttat ctccaacagt actctgatgg tatacttcta ttcccaatga
     4381 tgcaagttct ttagctaaaa attgagaatt tgtatttact atatctccca ataatatttc
     4441 tgttcctaca cttattattt cagctttcaa aatttatcac tccttgattt atagccatta
     4501 agactagtct taagttcata acaataattt tagcaaaaat aataacataa ataaagttaa
     4561 aaaatcattt aaacatatct ttaaactaga ttattattct aaaaccacac ataatataaa
     4621 cttcgtatat agtggtactt tcatcctcaa ctgttaattc atataattaa gtatgtaaat
     4681 aaaaagttta ctttaaaata ataaaaatta aaataggagt gtataatatg aaaatagcag
     4741 ttataatggg tggaatatca tcagagagag aagtttcttt aaattcagga aaagagatat
     4801 ataataacct tgataaaaat aaatatgaag ttgtaaaagt aataatagat gataaaaaag
     4861 atatatttac aaagatacca gaagatatag attttgcaat acttgcttta catggaaaat
     4921 ttggtgaaga tggatgtata caatcaatac ttgagactat ggatatacca tactctggat
     4981 gtggacctct ttgcagtggg atgtgtatgg ataaaaatat aactaaaaaa atgcttagag
     5041 attcaaacct acctactgct ccatgggttt tagtaaaatc agttgatgaa atagactatg
     5101 atgaaataga taatataggt tatccagtat ttataaaacc aaactcagga ggttcaagtg
     5161 tagccacatt ctttattcat tctaaggatg aagttgaaga agcagttaga aaaggtctgg
     5221 aagttgatga atttgtaatg attgaaaaat atataccagg tggagaatat acttcattca
     5281 tattaaatgg agaagtgttc cctacaatat ctataaaatc tgattcagga ttctttgatt
     5341 atgaagctaa gtactcagtt gaaaaaggtg caaaggaaga agttgtttac ttagatgaag
     5401 aacttcaaaa aagagtaaac gaaatttctg agacttgttg gaaaattttt aattgcaaag
     5461 catatgtaag agttgatatg attataagtg aaggtattcc atatgttctt gaactaaata
     5521 ctcttcctgg aatgactcaa actagtttaa ttcctagaag tgctgctgct agaggtatta
     5581 agtacagtga actattagat aaacttatag aatactcttt aaattagatg aaataatttg
     5641 aggtggtaat ttgatatttt caaatctaaa actaaatgat aatgaaccaa tttatataca
     5701 acttaaaaat tatataagtg atatgatatc aaaaggacta attccagaca atagtaagct
     5761 cccttctaca agggagctta gtcagctttt acaagttagc cgaaattctg tagttttaac
     5821 ttatgaagaa ttaaaatcag aaggattaat ctactctatt tcaggaaaag gtacatttgt
     5881 taaatcaaag aataagtctt caaatactac atggtcatta aactgggatt gtttagagaa
     5941 tacatactct aaaaaagcca atgaattgga cattataaaa agtgaaattc cttggagctc
     6001 tgacctgatt tcctttaaaa gtatttctcc agatggagat ttattcgaca tagaagaatt
     6061 aaaaaaatcc tttttaaata gaatttcact agaaggacat aaattactca actatggata
     6121 tgcacaaggt tataagcccc ttattgacta tttactagaa tatatgacaa ataagggtgc
     6181 tgatataagt aataaagata tactaataac aaatggattc acagaaggct ttgatattat
     6241 tatgtcatct tttacccaag aaaaagacta cataatatgt gaaaatccta ctcataatac
     6301 tgctataaaa attatgaaat ctcataacct caatatctta ggtgtagata taaatgaaga
     6361 tggtttggac ttcaatatgc tagaagacaa tttagttaag tataaaaata aaataaagtt
     6421 tgcatacatt acaccctctt atcacaatcc tacaggaatt gtaatgactc ctgaaaatag
     6481 gtacaaattc tataatctta tgaaaaaata caatatagca attatagaag atggatttaa
     6541 tgaagaatta ctctacaata gttctcatat atttcctatc tgttccctag ataatatgaa
     6601 taatggggtc gtatatattg gtagtttttc aaaaatttta tttcctggaa tgagaattgg
     6661 atggatattt gcagataaaa aagtaatcaa taagctagaa agtgtaaaaa ggtgcagaaa
     6721 catacatgta tcctttttgg accaaggaat tttatttgat tatttaagta atggaggttt
     6781 tgaaaaatac attaaaaaaa tacgtaaatt ctatggggac aaatttaact ttgcatataa
     6841 gtgtataaaa aaatatataa aaacagaata tatcttgggt gatggtggtt tgcatatatt
     6901 tataaaacta aaaaatatag atactagagt tttattagaa aaatgttatg aaaaaaatgt
     6961 tatatttatg cctggagatt tattttttac agataactct ggttttgata ctttaagact
     7021 cggattttct aggttgtctt ttgaagacat tgaaattgga ataaaaataa ttggagaaac
     7081 tataaatgaa atgttctagg ttaactaaat attgttagcc tagtttattt ttatgaggta
     7141 taatatatat agtttatatg aatctaatac tgggggataa tatgagtaaa aagtcaaaac
     7201 gaagaaaaat taataaatta aaattaacga ttgtaataac tgtattattt cttgctttat
     7261 tatctatata tgagatactg ttctctaatc ccaacaaaaa aggtaatata aagagtcaag
     7321 aaactatgca aaataaaaat aatacaacag atgattctaa aaataatcaa agctctacca
     7381 aaaagcagga agataataat atcaagccta ctttttcata ttcttcaata ccagataata
     7441 taaaaaataa aatgattggt aaatctatgc ctactgatga acctataagc tttgatagtc
     7501 tatcttattt aaaacttaca tattatggat ttgatgaaaa aactcatcaa ggagaaatga
     7561 tagtaaacag tgaactagct ccagaagtag tggatatttt taaggaatta tacgaaaaaa
     7621 aatatccaat tgaaaaaatt aagttaatag atgactatga tgctgtagat gaaaaatcta
     7681 tgtctgataa taatacctca tcattttgtt atagaactat agctggtaca aatgtagttt
     7741 caaatcatgg taaaggacgt gctatagata taaacccatt acagaatcct caagtttctg
     7801 gaaatgatgt tacacctaaa gtaagtacag tttatgctga taggtctagc acaaaatttg
     7861 gaatgataaa aaaaggtgat gattgttata atgcttttgt aagcagaggt tggagttggg
     7921 gtggctattg gaaaaaccca gattatcaac attttgaaaa ataatagatt agaaataaag
     7981 gtgaattata tgaatttaat gacattggaa aatataagta aaagctattc tgaaaaaaaa
     8041 ttactagaaa atatatctct tggaataaat gaaggggaaa aaataggact tattggtgta
     8101 aatggtactg gtaaatctac cttactcaaa attattgcag gagttgaaga aagtgagact
     8161 ggtaatataa caaaaactaa tggtattagg atagaatatc tacctcaaaa tccaacttac
     8221 aatgaaaatt caactgtact tgaacaagta tttaatggaa cttctgaaga attaaagcta
     8281 cttggtgaat atcaagaaat cctagaaaaa cttaattcaa actttacaga ggaattaaat
     8341 aaaaaattat tatcagtaca cgaaaaaata gatgccttaa atctttggga tttagaaagt
     8401 gaagctaagt cagtacttac aaagcttggt ataaatgact ttaatcaaaa aatagcagaa
     8461 ctttctggtg ggcaaagaaa gagagtctct ctggcatcag cccttattac accttgtgag
     8521 tttttgatac tagatgagcc tacaaaccat ctagacaatg atactataga ttggcttgag
     8581 gaatatctta attccagaaa aggctcattg cttatgataa ctcatgatag atacttttta
     8641 gaccgtgtta caaatagaat tattgaactg gacaaaggta gattattcag ttatgatggg
     8701 aattattcaa tatttttgga aaagaaaatg gaaagacttt cgctagaagc aagtattgaa
     8761 gataaaagac aaaatttaat aagaacagag cttgcgtggg taagacgagg agctcaggct
     8821 cgtagcacta aacaaaaagc tcgtttacaa agatttgatg aacttataaa tagagattct
     8881 tttaaacctg atgaaaatct tgatatatct gttgcatcaa gtagacttgg aaataaaata
     8941 atagaaatac acaatatatc taaatcattt gaagaaaata ctgttataga taatttagaa
     9001 tacactttaa ctcgtacaga tagaattggt ataataggca aaaatggtat gggtaaatct
     9061 acccttataa atatacttaa tggagaaata gagcctgata gtggatatat ttcaattgga
     9121 gaaacggtta aaataggttg tttttctcaa gacgactctc atatgaatat tgatatgagg
     9181 gctatagact atgtaaaaga agctagtgac tatatagaaa cttcagatgg tactaggatt
     9241 acagcttctc aaatgtgtga aagattcctt ttcaatggta ctatgcaata tactttgata
     9301 ggtaaattat ctggtggtga aagaagaaga ctacatcttc ttaaaatcct tatgacagct
     9361 cctaatgtgc ttcttttaga tgaacctaca aatgatttag atattgaaac gcttaaaata
     9421 ttagaagaat acctagacga atttaaaggt gtagtagtta cagtatcaca tgatagatat
     9481 ttcttagata gaatttgtaa taaaatattt gcatatgaag gtaatggaaa aattcatatc
     9541 tatacaggta attacagtga ttatcttatt tatagagaga ttcaaggaat tgaatttgaa
     9601 gaatctaaaa aggaatcagt taaaaaagat gactctacta ccctaaaaaa agaaaaacct
     9661 aaaaatgata aaaagcttaa gttctcatat aatgaacaaa gggagtttga aaatattgac
     9721 tctgatatag aaaaactcga atctaaaatt gcaacacttg atgaaagtac tgcaaaattt
     9781 tcaactgatt ttactaaact tcaagaaatt ttagatgaga aatctaaact agaaaaagaa
     9841 cttgaataca aatatgaaag atgggaatat ttaaataatc tagctgatga aatagctaat
     9901 aataagtaat attaaaataa tcttaagttt aataagtttt gctttaaatc tgtaatttat
     9961 aaatatttta aaggaagtgt ctcaaaatga actttttagt tttatgagac actctttttt
    10021 atgagaaatc aaatatattt tcatcatttc aacaatacaa aagaggctta tctctatttt
    10081 gagacagcct ctttcataat taccttctaa tttatatgct ctaatatatc tataataatt
    10141 cttattatat ctatatatcc agtctttcaa tataatgaca attaacttca atatgattta
    10201 aaaatactaa caacctttca taaagtggat gagattcttc tccatattta gcttctaggt
    10261 tcttgcctat ttctctaaca gtcctttgac catcaatttg taaaaaaaca aaactggaat
    10321 attcatctag ttctattttt ttgtatttag gtattctagc ttttaacttt ctaaaaaact
    10381 tttgaatttt atggtcctgt ttttcaagta tagtaacaac tctattttca gctacttcat
    10441 attcaagtcc atcagtaatt ttaaatacaa tatctaaaac atcattactc ttgctcatta
    10501 ttttttactt tagataaaac aataggtaat gctgtaagca caactaaaac tactaataaa
    10561 gcaattgcca ttgaatttgt tgcagcaaat ccacttggta cctttggagt tacaactcca
    10621 gttacttgta atattatacc tattaaacca atgatagaac caccagcaac aagaccagaa
    10681 gataaactta taccattaga aactttaact tctttttctt tttcagtttt agatactaat
    10741 tcaacaaata aacgaattaa tgctccaact aatattatag aagttgttgc aattggtaaa
    10801 tagaatccta tagctatagt cattattggt aaatttaatg catatagaac tattgccata
    10861 aatactccaa caataatcat aacccaaggt aaactacctg acataatacc agaagttaat
    10921 gttgacatta agtttgcttg tggtaatgca aattgtacat tatcaccagt tgctctaagt
    10981 tggtcagaaa gtaataaaat tactcctaca acaactataa caccaactat acttgcaatt
    11041 gtaaagtaac gttgcatttc gtttttgcta ccaccaataa tataagttac tttttgagat
    11101 tgagtataac ctccagctat agcaatagca acaactataa atgaaccaaa taaaagtaat
    11161 gatttattag cttctaaatc agtccatccc attataacaa acactaatgt tacaataact
    11221 agagaagcta tagtcatacc agaaactgga agatttgatg ttccgattgt tcctgttaaa
    11281 cgaccagcta ctatgacaaa taataaagat aataaaagag atatgatagc tccaataatt
    11341 gccataacaa tgttaccaga aattaagaat gctgctaaaa atccaataac tactccacct
    11401 aataaaagta tcatttgtat agatgaacct tcttctcctt ctccagcact tgatttagct
    11461 ttaagtgttt cttttataga agcgattata gttggtataa gttttattgc accaataata
    11521 cctccacaaa gcatcatacc agcacctata tattttacat aactactaga tattgctcca
    11581 acatccattt ggttaagagg cattgcagga ttattccata ccatagctcc atctttagcc
    11641 atatctgtaa agtatcctat taaaggtgct ataccaaagt ttgataaaat acttcctgca
    11701 aacattgtta aagaaacttc aagccctact ataaatccaa ttcctaaaag tagaggattt
    11761 acttcaatat caaatttcca tttgtagaat ttgcttccta caagactcat tacattgttt
    11821 gctacattta agaatgaacc agttaataca gtaataaatc cacttattac aaatccaatt
    11881 cccatgtact taattgaatc tccaccagcc tctgaagcaa caagtgtttc agatatagcc
    11941 attgattctg ggtacataag tttaccatgt tcttcaacta ttagatagtt gtgaactata
    12001 gcagcaattc ctataccaaa taaaactcca ccaactccaa cagctaagcc ttcaaagaat
    12061 gtaatttggc ttccaattaa tataactgct ggtaatacga aaataaatcc acttgcaaca
    12121 gattctccac cacttgacat accttggatt aagtttttac caagaatacc ctttgaacga
    12181 gcaaatgctc caacaaaagc agaacctatt atagctcctg gaatacctgc ggcaactgta
    12241 agaccggctt tcattccaga gtaagttgta gatgcggcaa aaatggcagc taaaataata
    12301 ccgataatca gtacagctac atttccaccg gttctggact tatctgtgat atatggaacg
    12361 taatcttttc cactaacctc accataagca cccttaggta attttttgtt cataaaattt
    12421 tcaccccttt tcaatttgta tatattataa catatataca tataaaactt aactttttat
    12481 tattttacaa atagcgagtc aaaactacta aaatttaacc ctatattatt aatttctact
    12541 tttagatatt tttatgctaa ttttcttttt atttttcaat tctactaaaa actattaaga
    12601 tataaaataa aaaaattttt taatgtaaaa ttaattttgt aaaaaaaatg ctttaaaaca
    12661 cggaaaagta taaaaaatac aataatcatt cttataaata aattttcacc atagtaaata
    12721 tatacagaaa attcttgttt ttatgcaaat tgattctttt ataaaaataa gtgtcataaa
    12781 gaaatgtctg aaatcacttt atgacaccta tcataataaa aaattattct ggtaatgctc
    12841 ttttatttac ttttccgatt ggtgtaactg gtatcttatc tatcctcatt attattgttg
    12901 gaatcatata tggaggtaga tgctcattta aatattctct aatagttctt tcatttatct
    12961 taccactatc ttcctcatca attacataat atgcacatat atacatatct ccatcatcat
    13021 ttgttctcga tatacaaaca acacttttaa tttctgtaat attatttatt atattttcaa
    13081 tctcatatag ctctatccta aactcatcaa tttttacctg attgtccatc cttccaatat
    13141 aatctaaatt tccatcatct aaccatctta ctaaatcacc agttctatac attaacttat
    13201 tatgttcaca agttttgtaa ggattctcta caaatacttg ctctgttagc ccttttttat
    13261 ttaaatatcc tcttgatatt tgaatgcctg atagacatag ctctcctggt gctccaattg
    13321 gacatagttt gttcttttta tctaatacat atgcataagt attaaatata ggttttccta
    13381 ttggtatttt tccatattct ctgtccacat gaaaagaagt cgatacaaca gtaaattcgg
    13441 ttggtccata ctcattatat agttcataat tacgctttct atatcctttt aatctttctc
    13501 ctccggtctg tacaactcta agtgaattat tattgcaatt ttgtataaat aaccttgcaa
    13561 atgctgttgg caatgctagt atagttatgt cattttcctc acagtattca tttactgtat
    13621 attcatcaaa tttagcttct tcaggcataa tatctattga tgcacctaca agcaaataag
    13681 ggaatagttg tttcattaca gcatcaaaac tgaaacttaa gtatatacca catatatcat
    13741 tttctgtagc gcttatagat tttacgctat aataacacat atttactaaa ctcttatgtt
    13801 ctatagctat ggtctttggc ctaccagttg accctgaagt agatatcgta tatgcacaat
    13861 ttgatgatgt tattttttca gttaattcat atccaagctt aaacatttct tcatcattta
    13921 tatcgagtac tatggtattc tcatttacaa ccttactttt gagttcatct gtagttatca
    13981 ctacttttgc attactatct tcaagaaggt aattcaatct ttcttctgga ttacttgtgt
    14041 ctattggaaa aaatgctccc cctgatttca taatccctat tgctgtaata attatgttaa
    14101 tatctcttgg taacattaca gctactatgt cttcactttc cactcctata tgatttaaat
    14161 aacctgcaag tttatcagtt acttcatcca attctttata tgttaacttt ctattttcat
    14221 ccctagcagc tatattacta ggtgttacct taacttgctc cctaaataaa tcaacataac
    14281 ttttatcata tggtatttca tattgattat tattaaagtc ttccaataat actttttctt
    14341 cttccttaca tacaaattct aaatcttcta ttaaaatatc attatcttct attatttgct
    14401 ctattatata atcaaattga tttaaaattc ttctaatagt ttctctttta tatatagatg
    14461 gtttatactt tatttttatt ttaagtgccc tcttagtata tactattaca gataaatcat
    14521 atcctttttt ttctatgtca taatcatatg ataaatcaaa acttttagct ataaatattg
    14581 tgtttataag cttagtattt agatgatttt tattctctat atctgataac aaatagtatc
    14641 catactctaa agacctgctc cactgccttt ttagcttcct tacaacatct ataaattttt
    14701 cactttgtct aactcttact cttattggaa ttatattcat tgttttacca aaaactacat
    14761 catcttcata tatatacttt tgaagtataa ggccatatat agtttctatg atagagtcta
    14821 tgctaatatt gttcacttta gaatattgaa ttaacctttc atgtttctca atattcatct
    14881 taaaaacctc atctactact tcatcagaac aatctttata aaaaaaatca tttggaattt
    14941 ttgctatatt cgtataatca tctaacaaat ccatccaata attcatagct cgttctaaat
    15001 taacttcata catatcaaaa ttccccctta ctactaagtc tatagaaaaa attcttttgg
    15061 aattttattt tcacaatata taaatatatt aataatacat atgcaagctc taaaaacatg
    15121 agcttgcata aaattacact tattatgact actaaattcg taatatttac aatgtttaaa
    15181 atatattata acacatatat gatttta
//
LOCUS       DAMJVG010000091        14973 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.094, whole genome shotgun sequence.
ACCESSION   DAMJVG010000091 DAMJVG010000000
VERSION     DAMJVG010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14973)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14973)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14973
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.094"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            56..1561
                     /gene="ade"
                     /locus_tag="PC512_003131"
     CDS             56..1561
                     /gene="ade"
                     /locus_tag="PC512_003131"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HDF2442860.1"
                     /translation="MSPGFIDAHMHIESTMVMPIELSKKLLKSGTTTIIADPHELVNV
                     KGVSAIDFLLESTKDIPLNVYIMVPSSVPATSFETNGVGKFSAKDMESYVNNPRILGL
                     GEVMCFNDVINSENEILDKLELFKNKVVDGHAPNINGKSLQTYVCAGIENDHECITFD
                     EVYEKLRAGLKILIREGSAAKNLKSIVSGMLKHNLPIEEFMFCTDDKHLDDIEKQGHI
                     RWNIKCAIDLGMEPVRAIKVATYNSAKAYGLRKIGAIGAGYKADIVVLNDLDKMEVDS
                     VYKDGNLVNEEMFSNYNYEIKDKELLNTVKFKYINKEKIQLKVSEKNYVMEIVPYQIL
                     TNKVYESLPCADGYFVPNKEYSKLCVVERHRMTGNVAVAPLKGFGIKNGAIATTVAHD
                     SHNIIVAGDNDDDILVAINYLKEIQGGYVIVSNGKVLAHLSLQVAGLISTFTAEEVQE
                     ITDNMLEIARKMGVPEYVDPFITLSFMALPVVPQIRLTDLGLFDVEEFKFI"
     gene            1913..2377
                     /gene="bcp"
                     /locus_tag="PC512_003132"
     CDS             1913..2377
                     /gene="bcp"
                     /locus_tag="PC512_003132"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002586316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-dependent thiol peroxidase"
                     /protein_id="HDF2442861.1"
                     /translation="MLSIGTKAPEFTLEDKDGNKVSMSDFKGKKVVVYFYPKDNTPGC
                     TRQACAFRNAYDGFKKEDIQVIGISKDSIKSHQKFAEKHELPFILLSDPDLVAIKAFD
                     VWKEKKMYGKTALGVVRATYIIDENGIIEKVFEKAKPDTNAQEILEYLEKQE"
     gene            2387..3130
                     /gene="yaaA"
                     /locus_tag="PC512_003133"
     CDS             2387..3130
                     /gene="yaaA"
                     /locus_tag="PC512_003133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HDF2442862.1"
                     /translation="MIIMLSPAKNMKNIEVFDRDLSLPCFIDNTKEIVENIKTFGIED
                     FKNKMKINEKLAVLNKNRFESIKFDRLGNPAILTYDGIQYKNIEAENFTRKDEEFANS
                     CIRIISGLYGVVKPYDSIYEYRLEMQTKLRVGEFKNLYEYWGNRIYKELIKEKTAIVN
                     LSSNEYSKSIEKFIKDSDTYITCTFKVNKNGILKVESTQAKKARGMMTKYIVKNRIRD
                     IEELKKFNLEGYKYKENLSNNSEYIFVKE"
     gene            3258..5915
                     /locus_tag="PC512_003134"
     CDS             3258..5915
                     /locus_tag="PC512_003134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HDF2442863.1"
                     /translation="MENHKQMPWHSRATHEILESLDSSEEGLTDTEAEKRLKENGLNE
                     LRKKPPRTTLQMLWSQITDAMVMILIGAAILSLIFGEFTEAFVILIIVTVNAVIGIVQ
                     EKKAESSLEALKNMNSPTARVMRDGEENVIPASNLVVGDIVFLEDGAMVPADLRLIET
                     SSLKIQEASLTGESVPSEKDADTILPKECVLGDRSNMAYTSSIVTYGRGVGVVVATGM
                     DTEVGNIAHLLDSQDDFDTPIKRKLNTVGKTLSVIGIIVCVVIFAIGAFYQRPLLPMF
                     MIAISLAISIIPEGLPATATIVMALGVQRMAKRNALIRKLPAVETLGGATVICCDKTG
                     TLTLNKMTVTHIAVNGDFESGKVTSIDTASEKHPLVYKEIVYAGALCNDACINPDKTD
                     EILGDPTEGALIFMAKKFGIDQEALEEEYPRVFEQPFDSDRKCMTTVHNIDEKIIAYT
                     KGAVDEILDLCTKILTSKGERNITEVDKKNIHELCLNMSKDALRVLGFAKREISSIPK
                     EDSENIEYDLTFIGMVGMIDPPRTEVIDAVSTCKEAGIRTIMITGDHKVTATTIAHEL
                     GIWSEENTVISGDELDNLSDDELDEAVKNTTVFARVSPFDKLRIIQSLKRIGEVPAMT
                     GDGVNDSPALKSADIGIAMGISGTDVAKDSSDMILMDDSFTTIAYAIKEGRRVYRNIQ
                     KVIQFLLVGNIAEILTLFVAILLNWDTPLLAVHILWVNLATATLPALALGVDPPSRNI
                     MKHQPVKSTTLFEKNLIQRVVTQGIFVAIMTILAYKIGLNIENHSVGQTMAFCVLAFS
                     QMLRAFSQRSNTDSMFNRNNGKNPFLLISFLTSAFLIAVILFAPVFRNAFNLTVLNNL
                     EWLITIVLAIMSVIQVEVGKIIKRKKLKK"
     regulatory      5969..6071
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            6181..7446
                     /locus_tag="PC512_003135"
     CDS             6181..7446
                     /locus_tag="PC512_003135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HDF2442864.1"
                     /translation="MYNKETICVQGNYKPGNGEPRVLPLYQSTTFKYSSIDQLAELFD
                     LKVDGHIYSRISNPTIQAFEEKISLLEGGVSSVAVSSGQSANMLAVLNICKSGDSILC
                     SSKVYGGTFNLLGPSLKKFGIDLISFDLDSSEDEIVELAKENTKVVFAETLANPTLEV
                     IDFEKIANVAKRINVPFIVDNSLASPVLCNPLKYGANIVTHSTTKYLDGHASSVGGII
                     VDGGNFNWDNGKFPELVEPDPTYHGISYTQKFGNAAYATKARVQLLRDYGNCLSPFNA
                     YLTNLNVETLHLRMERHSENALKIARFLEKHENVDWINYPGLEDNKYYENAKKYLSRG
                     CSGVLSFGVRGGLENAKKFVEKLQIASLVTHVSDVRTCVIHPASTTHRQLTEEQLIAS
                     GVLPSLIRLSVGIENVEDLIADLNQALNF"
     gene            7476..8366
                     /gene="metA"
                     /locus_tag="PC512_003136"
     CDS             7476..8366
                     /gene="metA"
                     /locus_tag="PC512_003136"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HDF2442865.1"
                     /translation="MALILPKGLPVINKLLDEGIDVIYKEDFKKELKYEENIDTKIAI
                     LNLMPIKIDTELDLLRRIDKTGFNVSVEFIKISTRESKRSCNEYVKEFYKTFDEAKGE
                     YFDGFIITGAPVEQMEFEEVDYWNELEEIMDYSKRKTKSTLYICWAAQASLYKYYNVK
                     KLPLSQKCFGVFKHKVDKDSKIVDGFENEFFAPHSRHTTVNIEALKENKELSIVSHSK
                     EAGPYIITNSRDVFVMGHSEYDKYTLDKEYKRDINKGDKISIPQNYYINDDPSEEPTV
                     KWKKHSELLFRNWIKNYLIQ"
     gene            8854..9297
                     /locus_tag="PC512_003137"
     CDS             8854..9297
                     /locus_tag="PC512_003137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2442866.1"
                     /translation="MDEMSFKKELLELTRDINMKFTTLLSDFYQPLGITAVQALILSE
                     LCEHGEKKISDLGKNLNMTNSNVSVICQRLEKNGFLNRIRDIEDQRIVKVKVTNKSLD
                     IQEHISSSIFDSYFENMTSEKLQDMEDIIEGLEKLNKLLTYIDCK"
     gene            9328..11145
                     /gene="ftsH"
                     /locus_tag="PC512_003138"
     CDS             9328..11145
                     /gene="ftsH"
                     /locus_tag="PC512_003138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HDF2442867.1"
                     /translation="MDEHKPQKRSALYYYTVIIIVVMFLNALIFPSLMDKKMVEIDYG
                     KFLTMLDTGKVKSVEIENNRIAINPSSSKDKNIYITGRMDDPELVDRLKNAKVEFTKV
                     IPKENSPLLSILLTWIIPIGILMLFGNLMMKSMQKRMGGNAMQFGKSNAKMYVSAQSG
                     KRFNDVAGQDEAKEALTEIVDFLHNPEKYKKIGAQMPKGALLVGPPGTGKTLLAKAVA
                     GEANVPFFSISGSEFVEMFVGMGASRIRDLFKQAKEKAPCIVFIDEIDTIGKKRDNGS
                     GLGGNDEREQTLNQLLSEMDGFDGGIGVVILAATNRPDSLDKALLRPGRFDRRIPVEL
                     PDLGGREAILKVHAQNVNVSSDIDYNAIARSTSGASGAELANIVNEAALLAVKSGRDI
                     VEQQDFDESVETVIAGYQRKGAVISDKEKKIIAYHEIGHALVAAMQKHSAPVHKITII
                     PRTSGALGYTMQVAEDESVLMSKEEAIDKITTFTGGRAAEEVIFNTCTSGASNDIEQA
                     TKIARAMVTRLGMSEEFDMVALETVSNQYLGGDTSLACSSDTAAKIDEEVFKIVKACH
                     KNAIEILENNIDKLHELANYLLEKETITGDEFMEILNLN"
     gene            11323..14025
                     /locus_tag="PC512_003139"
     CDS             11323..14025
                     /locus_tag="PC512_003139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase KdpD"
                     /protein_id="HDF2442868.1"
                     /translation="MDRPNPDILLEKIKNEEEKLSRGQLKIFFGYAAGVGKTYSMLES
                     AQNLKKVGVDVVVGYIEPHTRPETLALLDGLEILPVKEIEYKSIKLKEFDLDAALARK
                     PEVILVDEFAHSNVAGLRHTKRWQDIEELLLAGINVYTTVNVQHLESLNDIVEIITNV
                     SVKETIPDKFLDTNTQLELIDVEPDVLLERFNEGKIYKKEQATRAKNNFFIKDNLVAL
                     REIALRKTAERVNKEVQMTRLSKGDVTVIPTSDTLLACISPSPSSAKVIRTASRISDS
                     TFAKWIALYVETPNTARLPFDEQKQLQNNLKLAKKLGGEIIVLHGENIIEQILRIAKL
                     RNVTKIVIGRNHSSNKRFSKRFKKDIVDKLIDEVDYIDIHIIPYKFASDVKYKPKKDK
                     SSIKSKFKISKVDFIKLIFITLMISILAYAVQSMGFIRENILLIYMLGVVLVSMWTKG
                     YSTGIISSVFNIVLLNYFFTAPLYTLSIADSNYIVTLVVFSIVGIITSTLTSKIQHEA
                     ETAAKREENTKMIYQIIKGFLRLSNKDDIVNKGIELLSLSLSRDVICYLNVDKHNKSK
                     LYKKNTNNKDKNDLDSEDEKAVASWVLSNSTVAGNDTDTLPGSKGYYIPIVGMNLTLG
                     VVGISCIDSKLDTEDISLIETIIAQMAIALDREILSEAKENTNLEIERERLRSNLLRA
                     VSHDLRTPLAGISGAVSTIIKNKGTIGQDIIDELLSGVYEDTQWLIRLVENLLSMTKI
                     DEGKLEVKKHSELVEEIISEALQKIKKRIENALIDINIPEQILFVPMDAKLIEQVLIN
                     LIDNSLKYSKEDCKIEINVYEKDDYVWFEVSDNGPGISKELKKHIFDRFFTGEEGAKD
                     SRKGVGLGLSICKSIIQAHKGEIMVENNKDKGSTFKFSLPKENE"
     gene            14059..14757
                     /locus_tag="PC512_003140"
     CDS             14059..14757
                     /locus_tag="PC512_003140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2442869.1"
                     /translation="MSKKLILLVEDDKTIRKFISTALLTQDYDVKEAITGKEGISIAV
                     SYSPDVVLLDLGLEDMDGIEVIKAIRQFSNIPIIVVSAREQDRDKVEVFDAGADDYLT
                     KPFSIVELLARVRVAFRHSQVEAQQKDDVKSTFEVDKLLIDFDKRKVIVDDVEVHLTP
                     IEYNILSLLAKYHGKVLTHNFIIKEIWGSVIGNETKSLRVFMATLRRKIEKQPANPRY
                     IITEVGVGYRLNDE"
BASE COUNT         5860 a         1710 c         2739 g         4664 t
ORIGIN      
        1 tgaagcagga accctgtgac tttagtcatg ggaggttcag tgtagcaata aatatatatc
       61 acctggcttt attgatgcac atatgcatat tgaatctaca atggtaatgc caattgaatt
      121 atcgaaaaaa ttattaaaat caggtacgac aactatcata gccgacccac atgagttggt
      181 caatgtaaaa ggagttagtg caatagattt tttattagaa tcgacaaaag atataccact
      241 taatgtatat attatggtgc cttcatccgt acctgcaaca agttttgaaa ctaatggagt
      301 tggtaaattt agtgcaaaag acatggagag ttatgtaaat aatcctagaa ttttaggttt
      361 aggagaggta atgtgtttta atgatgttat aaattctgaa aatgaaatct tggataaact
      421 agagcttttt aaaaataaag ttgtagatgg acatgcacct aatataaatg gtaaatcact
      481 tcagacatat gtatgtgcag gaatagaaaa tgaccatgaa tgtataactt ttgatgaagt
      541 atatgaaaaa ttgagagcag gattaaaaat tttaataaga gaaggaagcg cagcaaaaaa
      601 tttaaagtct atagtaagtg gtatgctaaa gcataacttg ccaattgaag aatttatgtt
      661 ttgcacagat gataagcact tagatgatat agaaaaacaa ggtcacataa gatggaatat
      721 aaaatgtgcg attgatttag gtatggaacc tgttagggct ataaaagttg caacttataa
      781 ttctgcaaaa gcatatgggt taaggaaaat tggagcaata ggtgcgggtt ataaggcaga
      841 tattgttgta ttgaatgatt tagacaaaat ggaagtggat agtgtatata aagatggtaa
      901 tttggtaaac gaagagatgt tttctaatta caattatgag attaaagata aagaattgct
      961 taatacagtc aagtttaaat atattaataa agaaaaaata cagttaaaag taagtgaaaa
     1021 aaattatgta atggagattg taccttatca aattttgaca aataaggtat atgaatcttt
     1081 accatgtgca gatggatatt ttgttccaaa taaagagtat tcaaaacttt gtgttgttga
     1141 gagacataga atgactggaa atgtagcagt tgctccacta aaaggatttg gcataaaaaa
     1201 tggagcaatt gctactactg tggcccatga ttctcataat attatagttg caggggataa
     1261 tgatgatgat attctagtag ctataaatta cttaaaggaa atacaaggtg gttatgtaat
     1321 tgtatcaaat ggaaaagttc ttgcacacct aagtcttcaa gtagctggat taattagtac
     1381 ttttacagct gaagaagtac aagaaattac tgataatatg ttggagatag caagaaaaat
     1441 gggagttcca gagtatgtag acccttttat tacactttct tttatggcac ttccagttgt
     1501 tccacaaata agacttacag atttaggtct atttgatgtt gaggaattta aatttatata
     1561 gataatataa aagtaataat aaatgaggct ttctcaaaat agggataagt ctctttttat
     1621 tgttgaaatg ataaaaatat atttgatttc atacaaaaaa gagcatctca tgaactaaaa
     1681 attttatttt tagatatcct tattttaatt aatctatcat ttaaccttgt tttaagcata
     1741 gatatcttaa taaaactatt ttcagtctat tttaacatat aaatacatga aaattatata
     1801 tttatgaaac tttatacata aaaaataaaa tattttattt atatatagat ttatagggta
     1861 ataatataag catagtataa aattattaat aaaaacaaaa ggagagatat ttatgttgag
     1921 tataggaaca aaagcaccag aatttacact agaagataaa gatggaaata aggtaagtat
     1981 gtcagatttt aaaggcaaaa aagtagtagt atatttttat cctaaagata atacaccagg
     2041 atgtacacgt caagcttgtg cttttagaaa tgcatatgat ggatttaaaa aggaagatat
     2101 acaagttatt gggataagta aagatagtat aaaatcacat caaaaatttg cagaaaagca
     2161 tgaacttcct tttattttac tttctgaccc tgacttagtt gctataaaag cttttgatgt
     2221 atggaaagag aaaaaaatgt atggaaaaac tgcattggga gttgtacgtg cgacatatat
     2281 tatagatgaa aatggaatta ttgaaaaagt ctttgaaaaa gcaaaaccag acacaaatgc
     2341 acaagagatt cttgaatatt tggaaaaaca ggagtaataa gaatttatga ttataatgtt
     2401 atcaccagct aaaaatatga agaatataga agtatttgat agagatttga gtttgccttg
     2461 ctttatagat aacacaaaag aaatagtgga aaatataaag acatttggta tagaagattt
     2521 taaaaataaa atgaaaatta atgaaaaatt agctgtatta aataaaaata gatttgaaag
     2581 cattaaattt gatagattag gaaaccctgc aatcttaact tatgatggaa tacaatataa
     2641 aaatatagaa gcagaaaatt ttacaaggaa agatgaagag tttgcaaata gctgtattcg
     2701 aatcataagt ggattgtatg gtgttgtaaa accatatgat agtatatatg aatatagatt
     2761 agaaatgcag acaaaattac gagtaggtga gtttaagaat ttatacgaat attggggaaa
     2821 tcgtatatat aaagaactaa tcaaagaaaa aacagctatc gttaatcttt catcaaatga
     2881 atacagcaaa tccatagaaa aatttattaa agatagtgat acatatatta catgtacttt
     2941 taaagtaaat aaaaatggca tattaaaagt ggaatctaca caagcaaaga aagctagagg
     3001 tatgatgaca aaatacattg taaaaaatag gataagagat attgaagaac tgaaaaagtt
     3061 taatttagaa ggttataagt ataaagaaaa cttatctaac aatagtgaat acatatttgt
     3121 aaaagagtag aagttttgtt aaatattaaa tggcattgtt aaatttaggt aaaatatact
     3181 tagtgtgtat tgaattgaac ttgattttaa aatataatta ttcttaaatt aaaaaaagaa
     3241 aggagtggtc ttccaaaatg gaaaatcaca aacagatgcc ttggcattca agagcaacgc
     3301 atgaaatttt agaaagtcta gattcatcag aggaggggct caccgatacc gaggcggaaa
     3361 aacggcttaa agagaatggc ttaaatgaac ttagaaaaaa accacctaga acaactttac
     3421 aaatgctttg gagtcaaatt acagatgcta tggttatgat actaatagga gcagcaatat
     3481 tatctttgat atttggcgaa tttacagaag cttttgtaat actaataatt gtaacagtaa
     3541 atgcagttat tggaattgtt caagagaaaa aagcagaatc atcattagaa gcattaaaaa
     3601 atatgaactc acctacagct cgtgttatgc gtgatggtga agaaaatgtt attccagcaa
     3661 gtaatcttgt agtaggagat attgtttttt tagaagatgg agctatggtt ccagcagacc
     3721 ttcgtttaat agaaacatca agtttaaaaa ttcaagaggc ttctttaaca ggagaatctg
     3781 ttccatcaga aaaagatgca gatacaatct tacctaaaga atgtgtatta ggagaccgta
     3841 gcaatatggc gtatacatct tcaatagtca catatggtag aggtgtaggt gttgtagtag
     3901 caactggtat ggatacagaa gtgggtaaca tagcacatct tttagattca caagatgatt
     3961 ttgatactcc tataaaacgt aaacttaata ctgttggaaa gacattaagt gtcataggta
     4021 ttattgtatg cgttgttata tttgcaatag gtgcatttta tcagagacct ctcttgccaa
     4081 tgtttatgat tgcaatttcc cttgccatat caattattcc agagggatta cctgcaacag
     4141 ctactattgt aatggcttta ggcgtacagc gtatggctaa aagaaatgct ttaattagaa
     4201 aattacctgc tgttgaaaca ttaggaggag ctacagtaat atgttgtgat aaaactggta
     4261 cgttaacctt aaataaaatg actgttacac atattgctgt caatggagat tttgaatctg
     4321 gaaaagtgac atcaatagat actgcatctg aaaaacatcc attagtgtat aaagagattg
     4381 tttatgctgg tgcactttgt aatgatgcat gtattaatcc agataaaaca gatgaaatat
     4441 taggtgaccc aacagagggc gcattaattt ttatggccaa aaaatttgga atagatcaag
     4501 aagctcttga agaagaatat ccacgtgtat ttgaacagcc ttttgattca gatagaaaat
     4561 gtatgacaac tgttcataat atagatgaaa agattattgc ttatactaaa ggagcagtag
     4621 acgaaattct tgacctatgt actaaaatat taacttcaaa aggtgaaaga aacattaccg
     4681 aagtggataa aaagaatata cacgaattat gtcttaacat gtctaaagat gcattgcgtg
     4741 tacttggttt tgctaagcgt gagatttcat ctataccaaa agaagatagt gaaaatatag
     4801 aatatgattt aacatttata ggtatggttg gtatgattga cccaccaaga actgaggtaa
     4861 ttgatgcagt aagtacttgt aaagaagcag gtataagaac cataatgata acaggtgacc
     4921 ataaagttac tgccacaaca atcgctcatg agttaggaat atggagtgaa gaaaatactg
     4981 tgatatctgg tgatgaactt gataatttga gtgatgatga actagatgaa gctgttaaaa
     5041 atactacagt atttgctcgt gtatccccat ttgataaact tagaattata caatctctaa
     5101 aaagaattgg agaagtacca gcaatgactg gggatggtgt aaatgactct cctgccttaa
     5161 agtctgctga tattggtata gccatgggta taagtggtac agatgttgca aaagattctt
     5221 ctgacatgat tttaatggac gatagtttta caacaattgc ttatgcaata aaagaaggta
     5281 gacgtgtata tagaaacata caaaaagtta tacaattttt gcttgttggt aatatagcag
     5341 agatacttac gttgtttgta gcaatattat taaattggga tactccgctt cttgctgttc
     5401 atattctatg ggtaaacctt gcaactgcta cgcttccagc ccttgctctt ggagttgacc
     5461 caccaagcag aaatataatg aagcaccagc cagtgaaatc aaccactttg tttgaaaaaa
     5521 atcttataca aagagttgtt acccaaggta tatttgtggc aataatgact attttagcat
     5581 ataaaattgg tcttaatata gaaaatcatt ctgtaggtca aacaatggca ttttgtgtat
     5641 tagcattttc acagatgtta cgagcattta gtcagcgttc aaatacagat tcaatgttta
     5701 atagaaataa tggtaaaaat ccatttcttt taatctcatt tttaacttct gcatttttaa
     5761 tagcagtaat actatttgca cctgttttta gaaatgcttt taacttaaca gttttaaata
     5821 acttagagtg gcttataacg attgttttag ccataatgtc tgtaattcaa gtagaggttg
     5881 ggaaaattat taaaagaaaa aaattaaaaa aatagttgac aaaattagga aaaatatata
     5941 agatataaaa catagaaaaa ttaaataaat cttatccaga gaggtggagg gactggccct
     6001 atgaaacccg gcaaccagta tatttatata cagtggtgct aaatcctgcg gcgaaagctg
     6061 agagatgagt ataattaagc ttatacagag cctgagttat atactcaggc tttatttatt
     6121 ttaactctca tctggtaaat agtttaattt tttttactaa aatctaaggg ggatacaaga
     6181 atgtataata aagaaacaat atgtgtgcaa ggaaattata aaccaggtaa tggagaacca
     6241 agagtactac ctttatatca aagtacaact tttaaatata gcagtataga ccaacttgct
     6301 gaattatttg atttaaaagt tgatggacat atatattcaa gaataagcaa tcctactatt
     6361 caagcttttg aagaaaaaat aagtttacta gagggtggag tatcttctgt agctgtatca
     6421 tcagggcaat ctgcaaatat gttggcagtt ttaaatatat gtaaatcagg agatagtata
     6481 ctttgttctt caaaagtata tggaggaaca ttcaatttac taggacctag tcttaaaaaa
     6541 tttggtatag atttaatatc gtttgactta gattcaagtg aagatgagat agtagaactt
     6601 gcaaaggaaa atactaaggt tgtgtttgca gaaacacttg caaatccaac tcttgaagtc
     6661 atagattttg aaaaaatagc aaatgtagct aagagaatta atgttccatt tattgttgat
     6721 aattcattag catctccagt gctttgtaac cctttaaagt atggagcaaa tatagttact
     6781 cattctacca caaaatattt agatgggcat gcttcaagtg ttggaggaat tatagtggat
     6841 ggtggaaact ttaactggga taatggaaaa tttccagaat tagttgagcc agacccaaca
     6901 tatcatggta taagctatac tcaaaaattt ggaaatgccg catatgcaac taaagcaaga
     6961 gttcagttgc ttagagacta tggaaattgt ttaagcccat tcaatgcgta tcttactaat
     7021 ttaaatgttg aaacactaca tcttagaatg gagagacata gtgaaaatgc acttaaaata
     7081 gctagatttt tagaaaaaca tgaaaatgta gattggatta attacccagg acttgaagat
     7141 aacaagtatt atgagaatgc caaaaagtat ttatcaagag gatgtagtgg tgttttatca
     7201 tttggagtaa gaggtgggtt agaaaatgcc aaaaaatttg tggaaaaatt acagatagca
     7261 tctttggtta cacatgtttc agatgtaaga acttgtgtta tacatccagc ttcaactact
     7321 catagacaat taacagagga acaattaatt gcatctggag tattgccttc actaataaga
     7381 ttatctgttg gaatagaaaa tgtagaggat ttaatagctg atttaaatca agctttaaat
     7441 ttctaatatt ctaagagaaa gagaagtgaa aagatatggc tttaatacta ccaaagggat
     7501 tacctgttat taataaatta ttagatgaag gaatagatgt aatttataaa gaagatttta
     7561 aaaaggaatt aaagtatgaa gaaaacatag acactaagat agctatacta aatctaatgc
     7621 ctataaagat agatacagaa ttagatttac taagaaggat agataaaaca ggattcaacg
     7681 tgtctgtgga atttattaaa atttcaacaa gagaaagtaa aagaagttgt aatgaatatg
     7741 ttaaagaatt ttataaaaca tttgatgaag ccaaaggaga gtattttgat ggctttataa
     7801 taacaggagc tccagttgaa caaatggagt ttgaagaagt tgattattgg aatgaactag
     7861 aagaaattat ggattattct aagagaaaaa ctaaatctac attatatata tgttgggcag
     7921 ctcaagcaag tctttacaaa tactacaatg taaaaaaact tccactaagt caaaaatgtt
     7981 ttggagtatt taagcataag gtagataaag atagtaaaat agtagatgga tttgaaaatg
     8041 aattttttgc tccacattca agacatacta ctgtaaatat tgaagctttg aaagagaata
     8101 aagagttgag cattgtgagt cattctaaag aagctggtcc ctatataatt acaaattcaa
     8161 gagatgtgtt cgtaatgggt catagcgagt atgacaaata cactcttgat aaagaatata
     8221 agagggatat aaataaagga gataaaatat ctatacctca aaattactat attaatgatg
     8281 acccttcaga agagccaact gtaaaatgga aaaaacattc agaattgttg tttagaaatt
     8341 ggataaaaaa ctatttgata caataaattt taagagtata taaatgttaa ctaaaaaaat
     8401 atagaaattt ataggtataa agttaatctt aatgatactt tataccttat ttttttaaaa
     8461 tttgacctta taatagtagt tttatatttt aagaaaatca ctttaggtgt atgtagatag
     8521 aggtggcttt aattttatat atggtgcgat aatgggagac taaaccttta tagtatcaat
     8581 aaatttgtat tttaactttt aaaagagatt aaaaagggag aaatcagtgt aaaatatata
     8641 tagatttttt attaaatttt attaaaaata tcctgtataa aattaaatat caataagata
     8701 acaaaatttc aattgaagtt acaatattgt aattgacaat aaatacttaa tactataata
     8761 tttaatacat taaacattat agtgttaagt atttattaca gtatgcactt cagcctaaat
     8821 ttgaaataaa gtattttcgt agggagcgtt tgtatggatg agatgagttt taagaaagag
     8881 ctactagagt tgactagaga tataaatatg aaatttacaa ctttattaag tgatttttat
     8941 cagccacttg gtattacagc agtgcaagct ttgattttat ctgagttatg tgaacatgga
     9001 gagaaaaaaa taagcgattt agggaagaac ttaaacatga caaatagtaa tgtatcagta
     9061 atctgtcaaa ggcttgaaaa aaatggcttt ttaaatcgca taagagatat agaagaccaa
     9121 cgaattgtaa aagtaaaagt tacaaataaa tcattggata tacaagaaca tatttcaagt
     9181 agtatttttg atagttattt tgaaaatatg accagtgaaa aattgcaaga tatggaagat
     9241 ataatagaag gtttagagaa attaaataaa cttttaactt acattgattg caaataacat
     9301 aaaaataatt taaaggagaa taaaattatg gatgaacata aaccccaaaa aaggtcagca
     9361 ctctattatt atacagttat aataatagta gtaatgtttt taaatgcttt aatatttcca
     9421 agtttaatgg ataaaaaaat ggttgagatt gactatggaa agtttctcac aatgttggat
     9481 acaggaaagg ttaaatctgt tgagatagaa aataatagaa tagcaataaa tccatctagt
     9541 agcaaggata agaatatata cataactggt agaatggatg acccagaatt ggtagataga
     9601 ctaaaaaatg caaaagtaga atttactaag gttattccta aggaaaattc acctctttta
     9661 agtattttac ttacatggat aatacctata ggtattctta tgctatttgg taacttaatg
     9721 atgaagtcta tgcaaaagcg aatgggtggt aatgctatgc aatttggaaa aagcaacgcc
     9781 aaaatgtatg tatctgctca aagtggaaaa agatttaatg atgtagctgg tcaagatgag
     9841 gcaaaagaag ctttaactga aatagtagat ttcttacaca atccagaaaa gtataaaaag
     9901 ataggagcac aaatgcctaa aggagcactt ttagtaggac ctccaggtac aggaaaaaca
     9961 ctccttgcaa aagctgtagc aggtgaagca aatgtaccat ttttctcaat atctggttct
    10021 gagtttgttg agatgtttgt aggaatggga gcttctagga ttcgtgattt atttaaacaa
    10081 gcaaaagaaa aagctccatg tatagtgttt atagatgaga ttgatactat tggtaaaaag
    10141 cgtgataatg gaagtggatt aggtggaaat gatgaacgtg aacaaacttt aaatcagttg
    10201 ttaagtgaga tggatggttt tgatggtgga attggagtag taatacttgc tgctacaaat
    10261 agacctgaca gtcttgacaa agcattactt cgtccaggaa gatttgatag acgtatacca
    10321 gttgaacttc cagaccttgg aggacgtgaa gctatattaa aggtacatgc tcaaaatgta
    10381 aatgtaagct cagatataga ttataatgca attgcaaggt ctacatcagg agcatcaggt
    10441 gcagaacttg caaatattgt aaacgaagca gcacttttag cagttaagtc tggcagagat
    10501 atagtagaac aacaggattt tgatgaatct gttgaaactg taattgctgg gtatcaacgt
    10561 aaaggagctg taatttcaga taaggaaaag aaaattatag catatcatga aataggtcat
    10621 gcacttgttg ctgctatgca aaaacattct gcacctgtcc ataagattac tataatacct
    10681 agaacttcag gagcattggg atatactatg caagttgctg aagatgagag tgtacttatg
    10741 tctaaagaag aagcaattga taaaataact acttttacag gtggtcgtgc tgctgaagag
    10801 gttatcttta acacttgtac atcaggagca tcaaatgata tagaacaagc tactaaaatt
    10861 gcaagagcta tggttactcg ccttggtatg agtgaagagt ttgatatggt cgctcttgaa
    10921 actgtaagca atcaatattt aggaggagat acttctcttg cttgttcttc cgacactgct
    10981 gctaaaatag atgaagaggt atttaaaata gtaaaggctt gtcacaaaaa tgcaattgaa
    11041 atcttagaaa ataatattga taaattgcat gaacttgcta attatttatt agaaaaagaa
    11101 actattacag gtgatgagtt tatggaaata cttaacttaa actaaaatga ttatacacaa
    11161 gataaaaatg cctattgtta ggcattttta ttttacaact aaatttttta aattcatatt
    11221 taaatcttta cataatctta atcattaaaa atacatctta actacaattt tatatcggaa
    11281 ttgatattat aatagtaatg aatggtgtaa ggaggttttt taatggatag acctaatcct
    11341 gatattctat tagaaaaaat taaaaatgaa gaagaaaaac taagtagagg tcaattaaaa
    11401 atattctttg gttatgcagc tggagtagga aaaacctact ctatgttgga atctgcacaa
    11461 aatttaaaaa aagtgggtgt agatgtagta gttggatata ttgaaccaca cactagacca
    11521 gaaacattgg ctttacttga tggcttggaa attcttcctg taaaggagat agaatataaa
    11581 tctataaaac taaaagaatt tgatttagat gctgctttag caagaaaacc agaagttata
    11641 ttagtagatg aatttgccca ttctaatgtt gctgggttaa ggcatacaaa aagatggcaa
    11701 gatatagaag aattgctgtt agcaggcata aatgtctaca ctactgtaaa tgtacaacat
    11761 ttagaaagtc taaatgacat tgttgagata attacaaacg tatcagttaa agagactata
    11821 ccagataagt ttttggatac aaatacacag ttagaactta tagatgttga acctgatgta
    11881 cttcttgaaa ggttcaatga aggtaagata tataagaaag aacaagctac tagagcaaaa
    11941 aataattttt ttataaaaga taacctggtt gcacttagag aaatcgcact tagaaaaact
    12001 gcagagagag ttaataaaga agttcaaatg accagactat caaagggtga tgtaactgta
    12061 atacctacat cagatacact tcttgcatgt ataagtccat ctccatcttc agcaaaagtt
    12121 attagaactg catccagaat atcagacagt acatttgcaa aatggatagc tttatatgtt
    12181 gaaactccaa acacagcaag acttccattt gatgaacaaa aacaactaca aaataaccta
    12241 aaattagcta agaaattagg tggagaaata attgttttac atggtgaaaa tataatagag
    12301 caaatactta gaattgcaaa gctgagaaat gtaacaaaaa ttgtaatagg tagaaatcat
    12361 tcaagtaata aaagatttag taaaagattt aaaaaagata tagttgacaa attaattgat
    12421 gaagttgatt atatagatat acatataatt ccatataaat ttgcctcaga tgttaaatac
    12481 aaacctaaaa aggataaatc atcaataaaa tctaaattta aaattagcaa agttgatttt
    12541 ataaaactta tatttattac tttgatgata agtattttag catatgcagt acaaagcatg
    12601 ggatttataa gagaaaatat attgttaata tatatgttgg gtgtagtttt agtttctatg
    12661 tggactaaag ggtatagtac aggtataata agttctgtat ttaatatagt tcttttaaat
    12721 tattttttca cagcaccatt atatacatta tctatagcag attcaaacta tatagtaaca
    12781 ctggttgtat tctcaatagt aggtataata actagcactc ttacgtctaa gatacagcat
    12841 gaagcagaaa ctgctgctaa aagagaagaa aatacaaaaa tgatatatca aataattaag
    12901 ggatttttaa gattatcaaa taaagatgat atagtaaaca aaggtataga acttttgtct
    12961 cttagcttaa gtagagatgt aatttgttat ttaaatgtag ataagcataa taaatcaaag
    13021 ctttacaaaa aaaatactaa taataaggat aaaaatgatt tggatagtga agatgaaaaa
    13081 gctgttgcaa gttgggtttt atccaattca acagtagcag gaaatgacac ggatacactt
    13141 cctggttcaa agggatacta tataccaatt gtaggaatga atttaacttt aggagtagtg
    13201 ggaatatcat gtattgattc aaaattggat acagaagata taagcttaat tgaaacaata
    13261 attgctcaaa tggcaatagc gcttgataga gaaatcttgt cagaagctaa agaaaatacc
    13321 aatcttgaga ttgaaaggga aagattaaga agtaatcttt taagagcagt ttcgcatgac
    13381 cttagaactc cactagcagg aatatctggt gcagtaagta caattataaa aaacaagggt
    13441 actataggtc aagatataat agatgaatta cttagtggtg tatatgaaga tactcagtgg
    13501 ttaataagac ttgttgaaaa tttacttagt atgaccaaga tagatgaagg gaaattggaa
    13561 gttaaaaaac attctgaact ggttgaggaa attatatcag aagcgttaca aaaaataaaa
    13621 aaaagaattg aaaatgcact tatagatatt aatataccag aacagatatt atttgttcct
    13681 atggatgcaa aattaataga acaagtttta attaatttaa tagataattc tttgaaatat
    13741 tcaaaggaag attgtaagat agagataaat gtatatgaga aagatgatta tgtttggttt
    13801 gaagtatctg ataatggtcc tggtatatca aaggaactta aaaagcatat ctttgacaga
    13861 ttttttactg gagaagaagg agctaaagat tccagaaagg gtgttggact tggattatca
    13921 atttgtaaat ctataattca agctcataaa ggtgaaatta tggtagaaaa caataaagat
    13981 aagggttcaa cttttaagtt tagtttgcct aaggaaaatg aatagtttta aattttaaaa
    14041 ttagttttgg aggaagaaat gagtaaaaaa cttatattgt tagtagagga tgataagaca
    14101 ataagaaaat ttatatctac tgcactttta acacaggatt atgatgtcaa ggaggctata
    14161 actggaaaag aaggtatatc tatagctgtc tcatattctc cagatgttgt tcttttagat
    14221 ttaggcttag aagatatgga tggaatagag gtaataaaag ctatcagaca attttcaaat
    14281 ataccaataa ttgtagtttc agctagagag caagatagag acaaggtaga agtatttgat
    14341 gcaggggcag atgattactt aacaaaacca ttctccatag tagagttatt agcaagagta
    14401 agagtagcat ttagacattc acaagtagaa gctcaacaaa aagatgatgt taaatctacg
    14461 tttgaagtag ataaattatt gattgatttt gataaaagaa aagttattgt tgatgatgtt
    14521 gaagtccatt tgacacctat tgaatataat attctttcat tacttgcaaa gtatcatgga
    14581 aaagtgctta ctcataattt tataataaaa gaaatatggg gtagtgttat agggaatgag
    14641 actaagtctt taagggtctt tatggcaacg ttaagacgaa aaatagaaaa acaacctgca
    14701 aacccaagat atataattac agaagttggt gtaggataca gattaaatga tgaatagttg
    14761 taatatatta attattagat tatgtgctta ttaatatata ttaaaattat atagtttagt
    14821 taaaataaga atgaagtgta tgtgcttgtt gtcagtttag cacatgcatt ttatttttta
    14881 gcttttttag tatcaataat tttttagtat caataatatg aaatatgttt taaaataagt
    14941 atatagtgta atctgtaata aaaactttgg tta
//
LOCUS       DAMJVG010000092        14204 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.095, whole genome shotgun sequence.
ACCESSION   DAMJVG010000092 DAMJVG010000000
VERSION     DAMJVG010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14204)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14204)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14204
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.095"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            431..1324
                     /locus_tag="PC512_003141"
     CDS             431..1324
                     /locus_tag="PC512_003141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfide/dihydroorotate dehydrogenase-like
                     FAD/NAD-binding protein"
                     /protein_id="HDF2442870.1"
                     /translation="MSNKIVSKRQLTDSIYLMEIEAPRVAKSSQPGQFIIIKNDEKGE
                     RIPLTIADYDREKGTVTIVFQTVGASTKKLAMFEENDFVMDFVGPLGQASEFIHEDIE
                     ELRNKKILFVAGGVGSAPVYPQVKWFKEHGLDVDVIIGARTKELIILEDDMKKVAKNV
                     YVSTDDGTYGFNGRVTDLLKDLVDNQGKKYDQAIVIGPMIMMKFMCQLTKELNIPTIV
                     SLNTIMIDGTGMCGGCRVSVGNETKFACVDGPEFDGHLVDFDQAMRRQSMYKTQEGRA
                     MLKLEEGDSHHHSNCGCGGNK"
     gene            1324..2718
                     /gene="gltA"
                     /locus_tag="PC512_003142"
     CDS             1324..2718
                     /gene="gltA"
                     /locus_tag="PC512_003142"
                     /EC_number="1.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent glutamate synthase"
                     /protein_id="HDF2442871.1"
                     /translation="MDAKKVKVPVREQEPAVRATNFDEVCLGYNKEEAMAEANRCLAC
                     KKPKCVGGCPVGIDIPGFITKIKEDDIEGAAKVIAKSSSLPAVCGRVCPQESQCEGVC
                     ILGIKSDAVSIGKLERFVADWSKENDINLSDTEPKKNQKVAVIGSGPAGLACAGDLAK
                     KGYDVTIFEAMHEPGGVLTYGIPEFRLPKQAVVQPEIDNIRKLGVKIETNVIVGKTIT
                     VDELIEDEGFEAIFIGSGAGLPMFMNIPGENANGVFSANEFLTRVNLMKAYRDDYDTP
                     ISSGKKVAVVGGGNVAMDAARTALRLGSESYIVYRRSEKELPARAEEVHHAKEEGIIF
                     NTLTNPKEILVDENGYVKGMVCIRMELGEPDDSGRRRPIEIEGSEFVLDVDTVIMSLG
                     TSPNPLISSTTKSLDINKKRCLITDENGQTSKEGVFAGGDAVTGAATVISAMGAGKTA
                     AASIDEYLKAKVNA"
     gene            3084..5303
                     /locus_tag="PC512_003143"
     CDS             3084..5303
                     /locus_tag="PC512_003143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF2442872.1"
                     /translation="MKKREKVFDGLVFKHILILLILLVLIDLTSTIIYASNSMEITSR
                     NMIEASKRELENYLEVNISLLKALSQDDRFSNGETSLIEKGKLLSPYQKEYNLFMIGI
                     TDTKGNASSTYRENVNSIKDKPSFEKAIKTKQVVVSDIEVSNVTGDKVFIIYVPIVKN
                     NEMIGTIFASFYFQDVNNLISRSNFDDSIKFLMIDKDYTIISHPNKKYVNDKSKMLDL
                     EGNIIGTTKSEILKNINKKCQGDFLSWDNWRLYNVKYTNIKWTNWTLVSKCNIFKNFK
                     NLIVNFMIKLYFYIVIFMILWKLSNAKLIEQLKKLAYYDSLSGIKNKEKFRKDSMYIL
                     KNYYQDNFYLVQLDVNKFKYINEMFGYAEGNKILIHISQVLNNNTNKYEICARMDNDH
                     FILLIACNTEDELLNRLSKINKEICNLNTTNSSKYKIVMSSGIYKITKKDDIKKIDLL
                     IDRANIAAKSKKEKYEHSYSFFNEDTRNRLYKEKRLEDNMNKALEKGEFIVYYQPKYS
                     LDDVNEIEGAEALIRWNSPEFGFISPIDFVPLFEKNGFIVNIDMFVFEEVCKTLNKWI
                     NKGYTPVPISVNMSRVHLYRDNFIENITDLISKYNISPEFIELELTESVVFDNLNILI
                     DIMKKIKEIGFLISMDDFGSGYSSLNLLKDLSFDILKLDRGFLIETTDTKRGKIIISK
                     IVEMAKAIDIKVICEGVETYEQVEFLKEIGCDKVQGYLFAKPMVLDEFEKHLNFKFD"
     gene            5450..6196
                     /locus_tag="PC512_003144"
     CDS             5450..6196
                     /locus_tag="PC512_003144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2442873.1"
                     /translation="MNILSIRNISKTYCGNIPFKALDKVSLNIEKGEFVSVMGPSGSG
                     KSTLLNIISTVDRQSEGEVVLDGYDVSKLKGEKLAEFRRKQLGFVFQDFNLIDTLTVG
                     ENIMLPLTLEGASIKDMNIQTKSISKFLGIDKILDRKTYEISGGQAQRCAIARAIINK
                     PAILLADEPTGNLDSKSTDDVLKLFTRINKEQKVTTLMVTHEAYSASYSDRVIFIKDG
                     CIYTEIKKSESSNSFYSDILAVLSQIGGVR"
     gene            6196..8076
                     /locus_tag="PC512_003145"
     CDS             6196..8076
                     /locus_tag="PC512_003145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2442874.1"
                     /translation="MDFRKFAYNNIVRNFRAYLAYFLSSVFSIMIFFVFAVSMFHPII
                     TKSGMQSGSTAFMALMTSELIIFGFSLLFILYSLGNFLKYRLKDFGVLMIIGMSNRQL
                     KKLILIENLIIGFLAVMLGILLGLSISKLFLLYLSKLFYMNLTEFYFPVKAMLLTIVS
                     FMILFLITGPMSLKLLSKKSILELLVGTKKPKKEIKSSKLFGIIGVICLILGYAMILF
                     GNKLKINGGMYTTALLITLGIFLFFSQFTILILKYLKNKEKFYKNKVNMLLISNLIYK
                     LKDNTRLLFLITILLSATLVAFTTTSTLVSSQGEASKNNFPMVYSYFSEHNNEKEYEE
                     LQQIREAIKGYDYKELSFPVLKYNREVLLSVKNYNKLSKELGLDKISSKLEKYEGIII
                     PSSNSQEHINSLKQLKNYSIKNLNIEVKKSKNKIIFPTGLFSKVVVISDDLYNEVKGE
                     FSKINFHGFDYKNWQSSAKITENLKEKHFNLDREYNRSYFLTLPDMYLVELQQSKILQ
                     FMGVFIGVILFIAVFSFLYFRLYTDEIEDNVKYKKLSKIGLSFKNMNKIVSIEIGTLF
                     FIPYFIAIINSIISLLFLNQVLNNSFKLENLGILLLISSIYSLYFYLLKKNYTRKVWF
                     FD"
     gene            8195..9586
                     /locus_tag="PC512_003146"
     CDS             8195..9586
                     /locus_tag="PC512_003146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2442875.1"
                     /translation="MENQQLLGTERISKLLLKYSIPAIIGMLVNSLYNVVDRIFIGNI
                     PGVGPLAITGLGVTMPIMTIILAFGMLIGIGTTTTISIKLGQGKVEEARKLIGNAMTL
                     SVITGIIIMILGILFANKILTLFGASENTLIYAKSYINIILLGTVVNLLSFSLNHSIR
                     ADGSPKISAGIMIVGCLTNIVLDWILIFGFNLGIQGAAIATVTSQALTAILTIGYYIS
                     GKSNLRFSKSNLKLDKKLIKAVFAIGMSPFAMQLAASLVQVISNIALKTHGGDLAIGA
                     MATISSIAMVFLMPIFGINQGAQPIIGFNYGAEKYDRVKKAYLGSLVVATIILCMGMV
                     VVMLFPEAIIGIFNKDPELMNISVNGLRIYLLMLPIVGLSVTGTNFIQSIGKAKMAML
                     LSLLRQVILLIPAVLILPTFLGLQGVWTAQPVSDFIATVITGIVVFRELKRYTPKTEK
                     LNENERLNEITTE"
     gene            9693..10733
                     /locus_tag="PC512_003147"
     CDS             9693..10733
                     /locus_tag="PC512_003147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HDF2442876.1"
                     /translation="MEFTKKSKLKNMYVNMNVARMLSKINEYKGRQLLYKKQPKEILE
                     NLEKKSLVDCSESTYIGNQRDSSNFNLEKLISNEVTPRSREELSIVEYRDVVKTINSA
                     YESIPISSQTILELHGYLYKFSSTRGGSYKSDNDFIEHNLKPSEFISTDSSVNKVEKA
                     VEEICEAYNTLIEEDEIDILILISAFVLDFILIHPFKEGNIKMARVLILLLLNKNGYE
                     VGRYISLGKIFDDSSYEYYSNLNYLKASIGSEKADMNAWIEYFLETILTAYEKLDDSL
                     NISDKKRQTKTSRIEKIINSTLGYFTKEDIRDLCPDIPEPTINRVFNNLRKQDKIEVV
                     ARGRSAKWKKKY"
     gene            11222..11875
                     /locus_tag="PC512_003148"
     CDS             11222..11875
                     /locus_tag="PC512_003148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HDF2442877.1"
                     /translation="MKKKLLYINVNSKPEDLSSSKTVARKFINKFMEKNKDFEVEEID
                     LYKEHIPRLEYQYFEKRNSIVSEENAKNLDDKDRKELTKIRNLCDQFVNASVYVIAAP
                     MWSLSFPAPLKEYIDCIIQDGKTISFEGNDKPQGILNDIDRSMVYIQSSGGHIPWVLK
                     PVMNKGLNYVESIMKFIGIKKFDELLVDGTGTSEEERQAAIEKASEKIDGIIDGMKF"
     gene            11951..12160
                     /locus_tag="PC512_003149"
     CDS             11951..12160
                     /locus_tag="PC512_003149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442878.1"
                     /translation="MREEKSNEKYDCYWCNQENNFCVEIKDNIVMIDDGTGTLKQAVF
                     IGYKQIQINLNCSHCQNLNRIKLNL"
     gene            complement(12300..12866)
                     /locus_tag="PC512_003150"
     CDS             complement(12300..12866)
                     /locus_tag="PC512_003150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HDF2442879.1"
                     /translation="MMNNELNTIILETLNNADITSNDIPSIDLYMDQIISLIDNKLSA
                     NKRFESDKILTKTMINNYSKEGLIKPVKGKKYTKEQILQMIIIYSMKNTLTIQEIKRI
                     LHGVYEKDNFSEKDLVSCYEKFMLIKENQRKNIPDFIESNFENISINPENKDDLLIAL
                     LSLTSMADQLKNISEKLVDRYFPDITKK"
     gene            13027..13680
                     /locus_tag="PC512_003151"
     CDS             13027..13680
                     /locus_tag="PC512_003151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HDF2442880.1"
                     /translation="MYQFFLKGRDPISSLTHFIGACLSLLATIILVFQSVTLQETSLL
                     MIVSVSVFGLSLIALYSASSYYHFLKGTPEQELFFRKVDHAMIYVLIAGSYTPICLNF
                     MEKKEGIIFVTAIWIVAFIGIIIKIFWMDAPRWLSTSIYLLMGWAIVFDINAFNSIPK
                     DCLRLLIMEGVSYSIGAIIYIIKKPNISPEFGFHEIFHIFIMIGSLFHFLAVLLYVL"
     gene            complement(13838..14014)
                     /locus_tag="PC512_003152"
     CDS             complement(13838..14014)
                     /locus_tag="PC512_003152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442881.1"
                     /translation="MYKYDDYVNLTNDLDLPVEIRNKCVRIVSVSENLEDIIIVHKFK
                     LYVVNEKYIKGIME"
BASE COUNT         5564 a         1404 c         2380 g         4856 t
ORIGIN      
        1 aatatgaaag ctggtattgc aatagattaa agccttatac acgtttagtt tttaaagaaa
       61 ttagtgttat tatgaaaacc taagttaatt tattaaataa ataattgaat aaaaaaattt
      121 tattatgtat ttataaaatt tttgttacaa atttggcata atatagtata ctttaagtgt
      181 gtattaggtt aaatctataa caaattagac gtatgatata gacttagtgt ttattggcat
      241 ttacaagaaa tttgttaata tcaactattt gtagtttggg cagttataat tattataggg
      301 gggatgtcca atacaaaaca atcaaccaag aactaatatt atattataaa gagttatagt
      361 tttgtgtgtt tatgttttta attaaattta aagtgggaaa aatatatttg ttagaatgga
      421 gaatagcgag atgagtaata aaatagttag taagagacaa ttaacagata gtatttattt
      481 aatggaaata gaggcaccta gagttgcaaa atcttctcaa ccaggtcaat ttataataat
      541 taaaaatgat gaaaaaggag agaggattcc tcttacaata gctgactatg atagagaaaa
      601 aggaacagta actattgtat tccaaacagt tggtgcttca actaaaaagt tagcaatgtt
      661 tgaagaaaac gattttgtaa tggattttgt agggccatta ggacaagcaa gtgaatttat
      721 acatgaagat atagaagaat taagaaataa aaagatatta tttgtagctg gtggagttgg
      781 ttctgctcca gtttatccac aagttaaatg gtttaaagag catggattag atgtagatgt
      841 aataattggt gcaagaacta aagaattaat tatattagaa gatgatatga aaaaagtagc
      901 taaaaatgta tatgtatcaa cagatgatgg tacatatgga tttaatggaa gagttacaga
      961 cctattaaaa gatttagttg ataatcaagg taaaaaatac gaccaagcaa tagtaattgg
     1021 accaatgata atgatgaaat ttatgtgcca attaactaaa gaactaaata tacctactat
     1081 agtaagttta aatacaataa tgatagatgg aacaggtatg tgtggtggtt gtagagttag
     1141 tgttggaaat gaaactaagt ttgcatgtgt agatggtcct gaatttgatg gtcatttagt
     1201 tgattttgat caagcaatga gaagacagtc tatgtacaag actcaagagg gaagagctat
     1261 gctaaaactt gaagaaggcg atagtcatca tcatagtaat tgtggatgtg gaggtaacaa
     1321 ataatggatg ctaaaaaagt aaaagtacca gttagagaac aagaacctgc tgtgagagca
     1381 acaaattttg atgaagtatg cttagggtat aataaagaag aagctatggc agaagctaat
     1441 agatgtttgg cttgtaaaaa accaaaatgt gtgggtggat gtccagtagg aatcgacata
     1501 ccagggttta taacaaaaat taaagaagat gatatagaag gtgctgctaa agtaatagct
     1561 aagagcagtt cattaccagc tgtttgtggt agagtatgcc cacaagaaag tcaatgtgaa
     1621 ggtgtatgta tacttggaat aaaatcagat gctgtatcaa taggtaaatt agaaagattt
     1681 gtagcagatt ggtcaaaaga aaatgacata aatttatctg atacagagcc taagaaaaat
     1741 caaaaagtag cagtaatagg aagtggtcca gcaggtctag cttgtgctgg tgatttagct
     1801 aaaaaaggct atgatgtaac aatctttgaa gcaatgcatg agccaggtgg agttttaact
     1861 tacggaatac ctgagtttag acttccaaaa caagctgttg ttcaacctga aatagacaat
     1921 ataagaaaat taggtgtaaa aatagaaact aatgtaattg ttggtaaaac aattacagta
     1981 gatgaactta tagaagatga aggatttgaa gctatattca taggttcagg agctggtctt
     2041 ccaatgttta tgaatatacc aggggaaaat gcaaatggag tattttctgc aaatgagttt
     2101 ttaactagag taaacttaat gaaggcttat agagatgatt atgatacacc tattagttct
     2161 ggtaaaaaag ttgctgtagt aggtggtgga aatgttgcta tggacgctgc tagaactgca
     2221 ttaagattag gttcagaatc atatatagtt tatagaagaa gtgaaaaaga gcttccagca
     2281 agagctgaag aagttcatca tgcaaaagaa gaaggcatta tatttaatac attaacaaat
     2341 cctaaggaaa ttttagtaga tgaaaatgga tatgttaaag gtatggtttg tataagaatg
     2401 gaattaggag agccagatga ttctggaaga agaagaccta tagaaataga aggttctgaa
     2461 tttgtacttg atgtagacac agttataatg tcacttggaa caagcccaaa tccactaata
     2521 tcttctacaa caaagagtct tgatataaat aagaagagat gcttaataac agatgaaaat
     2581 ggtcagactt ctaaagaggg tgtatttgca ggtggagatg ctgttactgg agcagcaaca
     2641 gtaatatctg caatgggtgc tggtaaaaca gcagcagcat caatagatga atatttaaaa
     2701 gcaaaagtta atgcttaatt tgtaaattaa agagagggtg tctcaaaatg aactttttag
     2761 ttcatgaggc actctttttg tacaaaatca aatatgtttt aatcatttca acaatgaaaa
     2821 tttcattcct gtagaaagtc taacttttag gtcttagtac aatctctatt ttgatgtagc
     2881 cactttttta gatggtttaa taatttatca gttattattg taatatttga tactaagtaa
     2941 cataactttg tctaactatg ataaaatagt tatacaataa aggtcttgta aggagtgaat
     3001 aatgtgtggc taataaaatc agatttgtca aatctaacat taaataatag aaaaataaat
     3061 tgtgtaatta atggtatttt aatatgaaaa aaagagaaaa agtatttgat gggctagttt
     3121 ttaagcatat attaatctta ttaatactat tagttttgat tgatttaaca agtaccatca
     3181 tatatgcaag taactctatg gaaattactt ctagaaatat gattgaggca tcaaaaagag
     3241 aacttgaaaa ctatttagaa gtaaacatat ctttattaaa agctcttagt caagatgata
     3301 gattttctaa tggtgaaaca tcactaattg aaaagggaaa attattaagt ccatatcaaa
     3361 aggaatataa tctttttatg attggtataa cagatacaaa aggaaatgct tcaagtacat
     3421 atagggaaaa tgttaactca ataaaagata agcctagttt tgagaaagca attaaaacaa
     3481 agcaagtagt agtttcagat attgaagtca gtaatgtaac aggtgacaaa gtatttatca
     3541 tatatgtacc aattgtaaaa aataatgaga tgattgggac catttttgct tctttttatt
     3601 ttcaagatgt aaataattta ataagtagaa gcaattttga tgattctatt aaatttctaa
     3661 tgatagataa agattatact attatttctc atccaaacaa aaaatatgta aatgataaaa
     3721 gtaagatgct tgatttagaa gggaatatta taggaaccac taaaagtgaa atcttaaaaa
     3781 atataaataa aaaatgtcaa ggtgattttt tatcttggga taattggaga ttatataatg
     3841 taaaatatac gaacataaag tggactaatt ggactttagt atcaaaatgt aatatattta
     3901 agaactttaa aaatctaata gttaatttta tgataaagtt gtatttttat atagtaatat
     3961 ttatgatatt gtggaaatta agtaatgcta aattaataga acaacttaaa aaattggctt
     4021 attatgattc tttaagtgga ataaaaaata aagaaaagtt tagaaaagat tctatgtata
     4081 ttttaaagaa ttattatcaa gataattttt acttagtaca attggatgtc aataaattta
     4141 aatatataaa tgagatgttt ggatatgctg aagggaataa gatattaatt catatatcac
     4201 aggttttaaa taataataca aataaatatg aaatttgtgc taggatggat aatgaccatt
     4261 ttatattgtt gattgcttgt aacactgaag atgaactttt aaatagatta tctaaaataa
     4321 ataaagaaat ttgtaactta aatactacta actcatctaa gtataaaatt gttatgtcaa
     4381 gtggaatata taagattact aaaaaggatg atattaaaaa gattgacttg ttaattgata
     4441 gagcaaatat tgcagcaaaa agtaaaaagg aaaaatatga acattcatat tcatttttta
     4501 atgaagatac aagaaatcga ttgtacaagg aaaaacgatt ggaagataat atgaataaag
     4561 ctttagaaaa aggtgaattt atagtatatt atcaacctaa gtatagttta gatgatgtaa
     4621 atgaaattga aggagcagaa gccttgataa gatggaatag tccagaattt gggtttattt
     4681 cacctataga ttttgtacct ttatttgaaa agaatggttt tattgtaaat attgatatgt
     4741 tcgtgtttga agaagtatgc aaaacattaa acaagtggat aaataaaggg tatactcctg
     4801 taccaatctc tgtaaatatg tctagagttc atttatatag ggataatttt atagaaaata
     4861 taactgattt gataagtaaa tacaatatat ctcctgagtt tattgagctt gaactaacag
     4921 aaagtgttgt gtttgataat ttaaatatat tgattgatat aatgaaaaag attaaagaga
     4981 taggattcct tatatcaatg gatgattttg gttcgggata ttcatcttta aatctgttaa
     5041 aagacctttc ttttgatatt ttaaaattag atagaggatt tttaatcgaa acaacagata
     5101 caaaacgtgg aaaaattatt atttctaaga ttgtggaaat ggcaaaagcg attgatatta
     5161 aagtaatctg tgagggcgta gaaacttatg aacaagtaga gttcttgaaa gagataggtt
     5221 gtgataaggt tcaaggatac ttatttgcta aacctatggt attagatgaa tttgaaaaac
     5281 acttaaactt taaatttgat taatcattaa taattattag actataagat accctaacaa
     5341 cttacttaca aatatgtaag ttaattgtta gggtattttt atggttaaag tagtatattc
     5401 acgatattat ggtattgtag taaaaataaa aaattatgga gaatataaaa tgaacatatt
     5461 gagtattaga aatatatcaa aaacatattg tggaaatatt ccatttaaag cattagataa
     5521 ggttagtcta aatatagaaa agggagaatt tgtgtctgtt atgggaccat ctggaagtgg
     5581 taaatctact cttttaaata taatatctac agttgataga cagagtgaag gtgaggttgt
     5641 attagatgga tatgatgtaa gtaaattgaa aggagaaaaa cttgctgaat ttagaaggaa
     5701 acaacttggt tttgtatttc aggattttaa tttgattgac actttaactg ttggcgaaaa
     5761 tattatgttg ccacttacac tagagggggc aagtatcaaa gatatgaata tacaaactaa
     5821 aagtatatct aaatttttag gaatagataa aattttagat agaaaaacct atgaaatttc
     5881 aggaggtcaa gctcaaaggt gtgctattgc tagagctatt ataaataaac ctgccatact
     5941 tcttgcagat gagccaactg gaaatcttga ttcaaaatct actgatgatg ttttgaaatt
     6001 atttactagg ataaacaaag aacaaaaggt aacaacactt atggtaactc atgaagcata
     6061 tagtgcaagt tattcagata gagtaatttt tataaaagat ggttgtatat atacagaaat
     6121 aaaaaaatct gaaagcagta attctttcta ttctgatata ctagctgttt tgtctcaaat
     6181 aggaggtgta agatagtgga ttttagaaag tttgcttata ataatatagt tagaaatttc
     6241 agggcatatt tagcatattt tttaagttct gttttttcta taatgatatt ttttgttttt
     6301 gcagtgtcta tgttccatcc aattataaca aaatctggaa tgcagagtgg ttctactgca
     6361 tttatggctc ttatgacttc agaattaata atattcggtt ttagtctact ttttatattg
     6421 tactctttag gaaatttctt aaaatataga ttgaaagatt ttggagtatt gatgataatt
     6481 ggaatgagta acagacaact gaaaaaattg atattaattg aaaatttgat aataggattt
     6541 ttagcagtga tgttaggaat attacttggt ttatcaattt caaaattgtt tttattgtat
     6601 ttaagcaaac tgttttatat gaatttaact gaattttatt ttccagtaaa agcaatgcta
     6661 ttgactattg tatcatttat gattttattt ttgataacag gaccaatgag cttaaaatta
     6721 ttgagtaaaa agagcatttt agagctttta gtaggtacaa aaaagcctaa aaaagagata
     6781 aaatcttcaa agctatttgg aataattggt gtaatatgtc ttatattagg atatgctatg
     6841 atactatttg gcaataagtt aaaaataaat ggaggtatgt atacaacagc actattaatt
     6901 actttgggga tatttttatt tttttctcaa tttactattt tgatattaaa gtatttaaaa
     6961 aataaagaaa aattttataa gaacaaagta aatatgttac ttataagtaa tttgatatat
     7021 aaattaaagg ataatacacg attgttattt ttaataacaa tacttttatc ggctacttta
     7081 gtagcattta caacaacttc aacacttgta agttctcaag gagaagcttc taaaaataat
     7141 ttcccaatgg tttactcata tttttcagag cataataatg aaaaagaata tgaagaacta
     7201 caacaaatta gagaagcaat caaaggatat gattataagg agttaagttt tcctgtactt
     7261 aaatataata gggaagtctt actaagtgta aagaattata acaaattatc aaaggaattg
     7321 ggattagata aaattagttc aaagttagaa aaatatgaag ggattataat tcctagtagc
     7381 aattcgcaag aacatataaa ttctttaaaa caattaaaaa attatagtat aaaaaattta
     7441 aatatagaag taaaaaaatc aaaaaataaa ataatttttc ctacaggact gtttagtaaa
     7501 gttgtggtta taagtgatga cttatacaat gaagtaaaag gtgaattttc aaaaattaat
     7561 tttcatggat ttgattataa aaactggcaa agcagtgcaa agataactga aaatttaaaa
     7621 gaaaaacatt ttaatttgga tagagaatat aacaggtcat attttttaac attaccagat
     7681 atgtatttag tagagttaca acaaagtaaa attcttcaat ttatgggtgt ttttatagga
     7741 gtgatattat ttatagcagt ttttagtttt ttatacttca gattatatac agacgagata
     7801 gaagataatg taaagtacaa aaaactatca aaaataggtc tatcttttaa aaatatgaat
     7861 aagattgtta gtatagagat aggtacattg ttttttatac cgtattttat agcaattata
     7921 aatagcataa tttctttact gtttttaaat caagtattaa ataatagttt taagttagaa
     7981 aatttgggta tattactact gatatcatct atatattcac tttattttta cttattaaaa
     8041 aaaaattata ctagaaaagt ttggtttttt gattaaagtg gtatataata gatatataaa
     8101 ttaatattta aaaagtagtt aatattaggg gagggcattt gcacctccct tgtaatatgt
     8161 ggaaaattga atattagaag aaggaggaga cttgatggaa aatcaacaat tattaggaac
     8221 agaacgaatt agtaaattac tactaaaata ttctatacca gctataatag gtatgttggt
     8281 aaatagttta tataatgtag tagatagaat ttttattgga aatataccag gggttggacc
     8341 acttgcaata acaggtcttg gtgtaacaat gccaataatg acaataatac ttgcatttgg
     8401 gatgttgata ggtataggaa ctactactac catatcaata aaacttgggc aaggtaaagt
     8461 agaagaggca agaaaactta taggaaatgc aatgacgtta tctgtaataa caggaattat
     8521 cataatgata cttggaatat tatttgcaaa taaaatactt acattgtttg gagcaagtga
     8581 aaatacttta atatatgcaa aatcatatat caatattata ttattaggta cagtagtaaa
     8641 tcttctttcc ttttctttaa accactcaat aagagctgat ggtagtccta aaatttcagc
     8701 aggaataatg atagtaggat gtttaactaa tatagtttta gactggatat taatatttgg
     8761 attcaatttg ggaatacaag gagctgcaat tgctacagta acttctcagg ctcttacagc
     8821 tattttaact atagggtatt atataagtgg aaaatcaaac ttacgattca gtaaatctaa
     8881 tctaaaatta gataaaaagc taataaaagc agtgtttgca ataggtatgt cgccatttgc
     8941 tatgcaactt gcagcaagtt tagttcaagt aatatcaaat attgcactta aaactcatgg
     9001 tggagattta gctatagggg ctatggctac tatttcttct attgcaatgg tatttttgat
     9061 gcctatcttt ggaataaatc aaggagcgca acctattata ggtttcaatt atggagctga
     9121 aaaatatgat agggttaaaa aagcatattt aggttcatta gtagtagcta ctataatttt
     9181 atgtatgggt atggtagtag ttatgctttt cccagaagct attataggta tatttaataa
     9241 agaccctgaa cttatgaata tatctgttaa tggattaaga atatacttac ttatgttgcc
     9301 aattgtaggc ttatcagtta caggaacaaa ctttatacaa tctataggaa aagcaaaaat
     9361 ggctatgtta ttgagccttt taagacaagt aattttattg ataccagcag tattaattct
     9421 tcctacattc ttaggtttac agggtgtatg gacagctcaa ccagtgtctg attttatagc
     9481 tacagtaatt acaggtatag ttgtatttag agaattaaaa agatatactc ctaaaactga
     9541 aaaattaaat gaaaatgaaa gactaaacga gataactact gagtaaaaat ataaattcag
     9601 ataattgagc aagaaattgc aaaaaatacg attatatgat aaaataaaac cgctgtcaag
     9661 gataagagaa attctaatta tggagtgatt ttatggaatt tacaaagaaa agcaaattaa
     9721 aaaatatgta tgtaaacatg aatgtagcta gaatgttgtc taagataaat gagtataagg
     9781 gtagacaact gctttacaaa aaacaaccaa aagaaatttt agaaaactta gaaaaaaaat
     9841 ctttagtaga ttgttctgaa tctacataca ttggaaatca aagagatagt agtaatttta
     9901 atctagaaaa gttgataagt aatgaagtta cacctagaag tagagaggaa ttgagtattg
     9961 ttgaatacag agatgtggta aaaactatta acagtgctta tgagagtatt cccatcagtt
    10021 cacaaacaat tcttgagctt catggatact tatataaatt ttcatctact agaggaggaa
    10081 gttataagtc agataatgat tttattgaac acaatttaaa acctagcgaa tttataagta
    10141 ctgattcaag tgtcaataaa gttgaaaaag ctgtagaaga aatatgtgaa gcttataata
    10201 cattgataga ggaagatgaa attgatatat taatattaat ttctgcattt gtgttagatt
    10261 tcatattgat acatccattc aaagaaggta atataaaaat ggcgagagta cttatcctat
    10321 tgttactaaa taaaaatggg tatgaagttg gaagatatat aagtttagga aagatatttg
    10381 atgatagttc atatgaatat tatagtaatt taaattattt gaaagcctca ataggtagtg
    10441 aaaaagcaga tatgaatgca tggattgagt attttttaga gacgatatta actgcatatg
    10501 agaagctgga tgatagttta aatatatctg ataagaaaag acaaacaaaa actagtagaa
    10561 tagagaaaat aataaattct acccttggat attttacaaa agaagatata agagatttat
    10621 gtcctgacat tccagaacct actataaata gagtttttaa taatctaaga aaacaagata
    10681 agatagaagt tgttgcaaga ggaagaagtg caaaatggaa gaaaaaatat taaaaaatgt
    10741 ttagataact aaaatggtat agtgttttac actataccat ttttaatgtc attagcatga
    10801 gcaataattt aacaacttaa gcaatatcaa ttttatttat tgattatttt tgaactgaaa
    10861 aatggcgtta tatggtatac ctcagtggta attaattttg gatgagaaga tataatatta
    10921 cagaatatat taggagtata tgtagaaaaa atataataaa agtgtgaggc ttagtaatta
    10981 acaaattatg tggcttcaca cttttttata aaataaagat acttagcaga ataatatttt
    11041 agttgatatg tttataagat ggtacttgtt tgggtaaaag tataaatagt aaaaaagtag
    11101 aagtaatgtg tataaaaaca taagttacat tctgtaataa tagttatttt ataattcaac
    11161 aaaagaatag aatgggtata tttgtgaaat aataatataa aataatctta ggagtgagct
    11221 tatgaagaaa aaattattat atataaatgt aaattcaaaa cctgaagact tatcttcaag
    11281 taaaactgta gcaagaaaat ttataaataa atttatggaa aaaaataaag attttgaggt
    11341 tgaagagata gacctttata aagaacatat accaagactt gagtatcagt actttgaaaa
    11401 aagaaatagc atagttagtg aagaaaatgc taaaaattta gacgataagg atagaaaaga
    11461 gcttacaaag attagaaatc tttgtgacca atttgtgaat gcaagtgttt atgtaatagc
    11521 agcacctatg tggagtttat cttttccagc accacttaaa gagtatatag attgtataat
    11581 tcaagatgga aaaactatat cttttgaagg caatgataaa ccacaaggaa ttttaaatga
    11641 tattgataga agtatggtat atatacaatc ttctggtgga cacataccat gggtgttgaa
    11701 gccagttatg aataaagggt taaattatgt ggaaagtatt atgaaattta taggaattaa
    11761 aaaatttgat gaattgttag tagatggaac tggaactagt gaagaagaaa gacaagctgc
    11821 aatagaaaaa gcatctgaaa aaatagatgg tataatagat gggatgaaat tttaattata
    11881 atattttatt aaaaatataa aggaaaaacc tcttttaatg tagaaactta tattgaagga
    11941 ggcgagaatc atgcgagaag aaaaaagtaa tgaaaagtat gattgttatt ggtgtaatca
    12001 agagaataat ttctgtgtag aaataaaaga taatatagtc atgatagatg atggcactgg
    12061 tacgttaaaa caagccgttt tcatagggta taaacaaatc caaattaatt taaactgttc
    12121 acattgtcaa aacttaaata gaataaaatt aaatttgtag aattttaaaa tggaaattat
    12181 tgaaggaatt aaaaatagaa agtgttaata tttagactga aaattatatt ttatacaata
    12241 aaagtttatt taaataacat tgtattttaa tatttatttt cagtcttact ttattaaaat
    12301 tattttttgg ttatgtctgg aaaatatctg tctactaatt tttctgaaat attttttaat
    12361 tggtcagcca ttgaagtcag acttaataag gctatcaata aatcatcttt attttctgga
    12421 tttatactaa tattttcaaa attagactct ataaagtccg gtatattctt tctttgattt
    12481 tcttttatta acatgaattt ttcgtaacat gaaactaaat ctttttcact gaaattatcc
    12541 ttttcataca caccatgtaa gattctttta atttcttgta ttgtaagtgt atttttcata
    12601 gaataaataa ttatcatctg taaaatttgt tctttagtat acttttttcc cttaactggt
    12661 ttgattaatc cctctttgct gtaattattt atcatggttt tagtaagaat tttatcactt
    12721 tcaaatcttt tattagcaga aagcttattg tcaattagag aaataatttg atccatatat
    12781 aagtcaatag atggaatatc gtttgaagtt atatctgcat tatttagtgt ttctagtatt
    12841 atagtattaa gttcattatt catcatatgt tacctccata atatatataa tacactaaat
    12901 tagaaagtaa aacaatatta aggcttgtaa aaaaaacata aagtggtata attaaatata
    12961 taatatagta atcaaaacta tatttatgaa tctgattttt aaaatacata attgtaggag
    13021 gacgaaatgt atcaattttt tttaaagggt agagacccaa taagcagttt aactcatttt
    13081 ataggtgctt gtttatctct tttagcaact ataattttag tttttcaatc tgttacatta
    13141 caggaaactt ctctcttgat gatagtatct gtatctgtat ttggactttc actaattgct
    13201 ttatatagtg caagttcgta ttatcatttt ttaaagggga caccagaaca agaattgttt
    13261 tttagaaaag tagaccatgc aatgatttac gtattgattg ctggctctta tacaccaata
    13321 tgtctgaatt ttatggaaaa aaaagaaggc ataatatttg ttacagcaat atggatagtt
    13381 gcatttattg gcataataat aaaaatattt tggatggatg cacctagatg gttatctacc
    13441 agtatatatt tacttatggg gtgggcaatt gtttttgata taaatgcatt caattcaatt
    13501 cctaaggatt gccttagact attaattatg gaaggtgtat cttactctat aggtgcgatt
    13561 atttatataa ttaaaaagcc taatataagt cctgagtttg gatttcatga aatatttcat
    13621 atttttatta tgataggttc tttatttcac tttttagcag ttttattgta tgttttatag
    13681 ttttaaaaga tttgattaat tgatactaaa attctacaat gaataaaatg gaactgcctt
    13741 atatagatta tatcttagac aataagacag ttccttatta taaatattaa attctactta
    13801 taataaaatt ttgataaaaa tagtccattc aaaatgccta ttccataatt cctttaatgt
    13861 acttttcatt tacgacatat agtttgaatt tatgtactat aattatatcc tctaaattct
    13921 ctgaaacact aacaattctg acacatttgt ttctaatttc tacaggtaaa tctaaatcat
    13981 ttgttaaatt cacatagtca tcatatttat acataaaatc atccctttac attaagatat
    14041 acttattata ctatatttta ataagttttt ttaaattatt acaatttttc ccgaaatttc
    14101 attttttata cataaaattt ccaaattagg taaagattaa attttttatt gtataaacaa
    14161 aagttacata taaaatattt tattcaattt tttaaataac tatt
//
LOCUS       DAMJVG010000093        14056 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.096, whole genome shotgun sequence.
ACCESSION   DAMJVG010000093 DAMJVG010000000
VERSION     DAMJVG010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14056)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14056)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14056
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.096"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            <1..107
                     /locus_tag="PC512_003153"
     CDS             <1..107
                     /locus_tag="PC512_003153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF2442882.1"
                     /translation="EWICPSCNETHDRDINASINILKEGLRLITIQNK"
     gene            234..1136
                     /locus_tag="PC512_003154"
     CDS             234..1136
                     /locus_tag="PC512_003154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HDF2442883.1"
                     /translation="MLPQDYYGLIVILGVILGVMGAFYNWFTLYVQSLYKKIPKIGTF
                     GKLLIPFIMAGILGLVMPDVLGSGHNLVEELTSHEYIFGMVVLIFVIRFIFSAVSFGS
                     GAPGGIFFPLLVLGAFIGGIFGMVGVKVFGMNPDYVNNFVLLAMAGYFTAIVRAPLTG
                     IILIFEMTGSVSQMLSLSVISIVAYIVATLMKSKPIYESLLERLLEKNGEPVHKERGE
                     KILDQFSVMFGSPVANKAIQDVQWPENCLLVAIQRGGEEIIPRGKTILRPSDVIVTMT
                     DERDSGAVYDKMENLCKEHTSHIF"
     gene            1748..2761
                     /locus_tag="PC512_003155"
     CDS             1748..2761
                     /locus_tag="PC512_003155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HDF2442884.1"
                     /translation="MVSSFLNDIFRTILVSCIFIVILLVFRITLFKIFSKKFNYYIWL
                     IVIIKLSLPFMNYTFIFNESKYNGNINKISLGNFNSISIVYSTVLVSVWIAITIFYLV
                     YTLLKYIKLKNMINDLSYDVEDDKIKNLYENLLKELKINKKIRLKYSYEVESPVFFNS
                     CVILPPSDYTLKELNWIFRHELMHFKSKDLYIKYLVIFLKCVYWFNPFVYIMEKFIDL
                     DCEFYCDERVLKNCTIEEKQDYALTIISAMRKGSNSSNKFVAGLHKESDIKKRVFSMF
                     NEKYRNGILIAVILCLLSSITYFKIDLITTKSIFYPLSKQTPIENRTNSKPTYQINVY
                     IDN"
     gene            3117..3686
                     /locus_tag="PC512_003156"
     CDS             3117..3686
                     /locus_tag="PC512_003156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrpB family protein"
                     /protein_id="HDF2442885.1"
                     /translation="MKKKLEDMTLEELWNLFPIFLTTHKECWKNWFKEEQYRLTGILP
                     MQKIVRISHIGSTSVSTIYAKPIVDILIEIIPDYNMKDIKDLIESNGYICMSESSSRL
                     SLNKGYTVDGFEERVFHLHIRYVGDNDELFFRDYLIDHPDVAKEYEKLKLDLWKKYEH
                     NRDAYTDSKLDFVREFTEKAKVLYFNRYN"
     gene            complement(4022..5359)
                     /locus_tag="PC512_003157"
     CDS             complement(4022..5359)
                     /locus_tag="PC512_003157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDF2442886.1"
                     /translation="MGTYSLISTSINFILILINIFIAFFLYTLTSYFIDFRNHWIFKI
                     ILILGYSIISQMIIWLSDPVNILFTLFGYFILLIICSKSKLIPIISVVMIFYPIIIGL
                     NFLFINNPIYEELIHSKEYILILSIVQIISALIKLLFWFLIHIFLKNRLVNIKQYLSN
                     KIWIFIDMVCISSFLSILIAIILPPTNLIPMGSNKNIILGNLPYGTYLIILSAILANI
                     GVILLLQPLIENVKMKIEKQANHLKEKYYNLLENQQIQIRKMRHDMNNHFQMIESYLE
                     IEDIAGAKKYFNQLKIGIGTLSGKQFCKNQALNSILNLRHTSLEENGVDVHFNIDIDN
                     HLGIEPIDLCTIFSNSLDNAIEASLKIPDLSNRKVVLKARCEKEYFSYLLTNNKVNPI
                     NRKQELFISDKKDSNSHGYGIENIREIVNKYNGKLDISYTENEFSLFLYIRLF"
     gene            complement(5803..6513)
                     /locus_tag="PC512_003158"
     CDS             complement(5803..6513)
                     /locus_tag="PC512_003158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2442887.1"
                     /translation="MTSICICDDEKQQRNMLNKIITREMDLWGYPYQIKEYSNGESLV
                     YNLEHENYYIDIIFLDIELGKSNGVDIAKTIRKHSKDTIIIFVTGFSDYVFHGYDVGA
                     LNYILKPYKTEKICKVLKEALKKLEQWKENFITVQIGTNLCKINTKDILYFKSELRKL
                     TVVTFDKTLEYYGKLNDMETVLPSNFIRTHQRYIVNLNHVDSITQTYAKVQNEKIPIS
                     RKKYQEVVGKFTRYMLEP"
     gene            complement(6897..9008)
                     /locus_tag="PC512_003159"
     CDS             complement(6897..9008)
                     /locus_tag="PC512_003159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2442888.1"
                     /translation="MTINKLYSKLRAYNWKNYTTLFFCIILSVVLVTSYALIYFSPTI
                     QNILPTGGDSRKQATMIFSVAILGCAVFTTYASSLFLKFKSKEIGIFMALGTDKKKLK
                     KLLFSEILLISIVCCFLGLILSIPVSFGIWKIFQLVIIDTREMTYHFGTQGFIYGFIF
                     SVFVTLCIFILSVKFINRTNIIDILNDQRISEPIQDVKDWYGILGIIFIILGIFLGYL
                     VPSLTINKLNYKLPSIWSFTYLLSLIGIYMIMTYIVVHAKRGKHPEKYYKNIISTSMM
                     RFMGRQTVKNMCVISFLIAGALFAVFYVPNMVTGIYDTLKNNPIDYTFTYNQRDKQVS
                     KKDIEQLADKHNIKIQNYMEIPSIELIVDGVESIYHKDGTIEKVYMKKSSYDMFFNSK
                     DFSKLIGKPITIKNGEYLAVVNKGNENQDYKYTKFISSPVTEKEIPFRYAGKIIFNGS
                     FFQNRSMNAYVLNDEDYKSFTKDLSIKNYNNSILFNVDKDTYAFANDLKKEIIKRTSK
                     EMGMFSGYDEYVKKRYESTGRKYFMDEEYPSGEGHLKLDPNNNQLYLNWKYYPNFKIL
                     QSQDMIKNMAVFLMLFIYVAIICFTAVGIIAYTRGVTIAINHKQVFMDLNRLGANNDY
                     IKFCIRNQLKKVFSYPLIAGSFLIYLFNFMIMLNNDGRIVNSEVNALLINLGFIGICG
                     VYMYLIYLLTYKKFKKIIGIL"
     gene            complement(8998..9750)
                     /locus_tag="PC512_003160"
     CDS             complement(8998..9750)
                     /locus_tag="PC512_003160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2442889.1"
                     /translation="MLKVNQLCKSYKTGSKTYPVLKNISFEINKGEFVAIMGSSGSGK
                     TTLLNCISCFIPIDNGEIILGNNNIRNLKEKELSEVRNQQLGFVFQDFMLFDGLSVFE
                     NICVPQIIKGSQVLQMENRAINLCELFGIEHIRKKYPAEISGGEKQRTAVARALMNNP
                     DLILADEPTGNLDSKSCRTVIESFLKAKQELDATILMVTHDSFAASFCDRVIVLKDGI
                     IYKEVVKSNSRHKFLDELLEVLKEMGGAQDDN"
     gene            complement(11016..11192)
                     /locus_tag="PC512_003161"
     CDS             complement(11016..11192)
                     /locus_tag="PC512_003161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442890.1"
                     /translation="MFFTFIGVISAILLLCTIICGLWIKLNNRNNDSNSHFTFSILSI
                     AFSLLIVVAFLVRN"
     gene            complement(11296..11904)
                     /locus_tag="PC512_003162"
     CDS             complement(11296..11904)
                     /locus_tag="PC512_003162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2442891.1"
                     /translation="MGKLLRGKIMKADSTKEQLINATIQLLSSHRDVSSITAREIVAK
                     ANVNLAMINYYFKSKEELINISIKKFLKRHMDEYKATHDTKNLAPKQQLREILIAFFD
                     FIGEHSQFIKISVPYILIQEEIVYPFEILPLIKAHYENQNNKKTEAEYRTIAYQITSF
                     IQLLFLRSNAFFKYSGIDILNIEQRNGLIDFQLDLLLVDITK"
     gene            complement(12003..12827)
                     /locus_tag="PC512_003163"
     CDS             complement(12003..12827)
                     /locus_tag="PC512_003163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2442892.1"
                     /translation="MFKIGEVSKLTQISIRMLRYYDELGILKPAEIDKYTGHRLYSVE
                     QISILQRIVLLRDSKFSVAEIANIVHNWNDEFVIKELNRKKNEIQKEINQEQQRINKI
                     DKFIEAINCDKDEIHYNVVFKKIPSYKIISLREIIPDYQSEGILWEKLSKFIKEEHIE
                     VSRQSNNNIAFYHDEEVKDNGVDIEVGMVVKKIGKNKSGFIYRETEEIDMMACTMVYG
                     PYENIAGAYESFCYWLDKNSDYQISGINRQIGHKGEHNEINPENYLTEIQIPLIKV"
     gene            complement(13005..13898)
                     /locus_tag="PC512_003164"
     CDS             complement(13005..13898)
                     /locus_tag="PC512_003164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDF2442893.1"
                     /translation="MQLYNTPFNTNKHLIYFFTFTLVLNWIFSLTPALLGITNTILGE
                     IIFYLAYTSPAIVGLFFISTIYPQSAKQDFIYRYLSFKEIRIKWILLTILFFALTFIT
                     SLIIGNYFNVKTSDIDWIHIAVFRPSKIAYMLLASFILSILSQEAGWRGYAIDKLLVR
                     FGFIGSSIILGLVCGIWYLGSYFTPNQIPYNLAQYSLFDAFLFIPNIVLLNFIINFVY
                     INTSRSILSAGLVHMMYYFFNIQLLLHYPIKLCVIAQYVQIIFGLIFLVYMISSNKFK
                     QKVNSEIEQIKSDDFEFELDW"
BASE COUNT         5161 a         1680 c         1996 g         5219 t
ORIGIN      
        1 gagaatggat ttgtcctagt tgtaatgaaa ctcacgatag agatataaat gcaagtataa
       61 atatattaaa agaaggatta agactaataa caattcaaaa taaataactt atgtaagaac
      121 cgtaggaact acggggatag cctgtggaga attagtaaga catatgttag tatgcaaaat
      181 tctatgaagc aggaaccctg tgactttagt catgggaggt tcagattgga aatgtgttgc
      241 cacaagatta ttatggatta atagtgattt taggtgttat tcttggagtt atgggggcat
      301 tttacaactg gtttactcta tatgtgcagt ctttatacaa gaagattcct aaaattggta
      361 cgtttggaaa actgttgatt ccatttataa tggctggtat tcttgggctt gttatgcctg
      421 atgttctggg gagtggacac aatttagttg aagaacttac aagtcatgaa tatatttttg
      481 gaatggttgt tttgattttt gttatacgtt ttatattttc ggctgttagt tttgggtcag
      541 gtgcaccagg gggaatattt tttccattgc ttgttttagg agcatttata ggtggaatat
      601 ttggtatggt aggtgttaaa gtttttggaa tgaatcccga ttatgtaaat aactttgtgc
      661 ttttggctat ggcaggatat tttacagcta ttgtgcgtgc ccctttgact ggtatcatat
      721 taatttttga aatgacaggt tctgttagtc aaatgctttc actatcagta atttcaattg
      781 tggcatatat tgtggctaca cttatgaagt ctaaacctat ttatgaaagt cttcttgaga
      841 ggttacttga aaaaaatgga gaacctgtac ataaagagag gggcgaaaag atattagacc
      901 agttctctgt tatgtttggc tctcctgttg cgaacaaggc aattcaggat gtacagtggc
      961 ctgaaaattg tcttttggta gcaattcaaa gaggtggaga agaaattatt cctagaggta
     1021 agacaattct tagaccaagt gatgtaattg tgactatgac agatgagaga gatagtggtg
     1081 ctgtgtatga taagatggaa aatttgtgta aagaacatac gtcacatatt ttttagggat
     1141 aatgatgaat gtttaataat gatagaatat ttaatgaaga tttgattaaa aaattggtaa
     1201 tttgaaagag agttaaggaa ttaatataag aaaatgaaaa tgtgatatct tagatgtaaa
     1261 agagtttgaa gaaaataatt gtatatattt gttaatgaga ttatatggac taatggtata
     1321 tttatactgt gctaaaagtt gcactattgt atgaggaatg ggaataaagg gtttgaaaaa
     1381 ataggtagaa gatttttcag atattcttac tgggatattt taattaatat attttaattg
     1441 cgatattttg ggaagaatag aatttattta taaatgaaaa taattaaaag gggttaaggt
     1501 tgtattagcc ccttttgctt atagagtttg gaaatggtat cttgatagca gttgtttcat
     1561 gcttattata ttttattaca tattttaaaa ttgaccttat tactcctaaa tcattgttat
     1621 atcaactttt aaaacacttt caagacaatc gcctattgaa aacaaagtta attaaaaacc
     1681 tacatatcag tttagtattc gtgtagatga ttatataaat ataaaagtat aagaaaggtg
     1741 agtatctgtg gttagttcat ttttaaatga tatctttaga acaattttag taagttgtat
     1801 ttttatagtt attttattag tctttagaat aactttattt aagattttca gtaaaaaatt
     1861 taattactat atatggctta ttgtgattat taagctatca ttaccattta tgaattatac
     1921 ttttatattt aatgagtcaa aatataatgg taatattaat aagataagtt taggcaattt
     1981 taatagtatt tctattgtat atagtactgt tttagtctct gtttggattg ctattacgat
     2041 attttattta gtttatactt tattgaaata tattaagctt aaaaatatga taaatgattt
     2101 gtcttatgat gttgaggatg ataagataaa aaatctttat gaaaatttat taaaagagct
     2161 taagataaat aaaaaaatac ggcttaaata ttcatatgaa gttgaaagtc cagtattttt
     2221 taattcgtgt gtcattttac caccaagtga ttatacatta aaagagttaa actggatatt
     2281 taggcatgag ttgatgcatt ttaagagtaa agacctttat attaagtatt tggtgatatt
     2341 tttaaaatgt gtttattggt ttaatccttt tgtgtatata atggagaagt ttatagattt
     2401 ggattgtgaa ttttattgtg atgaaagagt tttgaagaat tgtacgatag aagagaagca
     2461 ggattatgca ttgacaataa ttagtgcaat gagaaaaggt tcaaatagtt caaataaatt
     2521 tgtggctgga ttacataagg agtcagatat taaaaaaaga gtgtttagta tgtttaatga
     2581 aaagtacaga aatggtattt tgatagcagt tattttatgt ttattatctt ctattacata
     2641 ttttaaaatt gatttaatta ctactaaatc aatattttat ccactttcaa aacaaacacc
     2701 tattgaaaac agaactaatt caaaacctac atatcagatt aatgtttata tagataatta
     2761 aaaaatacaa agtttaacaa gagattaata taaataattt taataagtat ctttcacata
     2821 tgttaaattt actttaatta tattaaagcc aatgaattat tctttagaag ctccaatgcc
     2881 agtaaataca ggtaaagaaa aatattttac tacaattgca gattaaaaag tgttctaata
     2941 tttaaagaaa tacacaagtg taagaagggt aaaaatctgt tataatacat taaaaactaa
     3001 atttagaaaa atttacataa ttagaaaaat gatttgataa aaaataaagt taaatattaa
     3061 ctaagtaaat ttgaaaaaga aaaaatataa agtacaaatt taaaaggagg taactaatga
     3121 aaaagaagtt ggaagatatg actttagagg agttatggaa cttgtttcct atatttttga
     3181 ctactcacaa agaatgttgg aaaaattggt ttaaagaaga acaatataga ctaactggaa
     3241 tattgccaat gcaaaaaatt gttagaataa gtcatattgg aagtacttct gtgagtacga
     3301 tttatgccaa gcccattgtt gacatactga ttgagataat tcctgattat aatatgaaag
     3361 atattaaaga tttgattgag tcgaatggat atatttgtat gtctgagagc agtagtaggc
     3421 tttcacttaa taaagggtat acagtagatg ggtttgaaga acgagttttt catttgcata
     3481 taaggtatgt aggtgataat gatgagttgt tttttagaga ttacttaatt gaccacccag
     3541 atgttgcaaa ggagtatgaa aaacttaagt tggacctttg gaagaagtat gagcataatc
     3601 gtgatgctta tacagatagt aaactagatt ttgttaggga gtttactgaa aaggcaaagg
     3661 tgttgtattt taatagatat aattagaaat aggtacaatt agatatttat cttatatatc
     3721 gtattatatt ttttaagaaa gtaattaata gaaaaagggg ttgtttcaaa atggagagat
     3781 aaatcccttt ttcattgttg aaaggataaa aatatatttg atttcatgta aaaaagagtg
     3841 cctcatcaac taaaaagttt attttgagac acacacattt ttactaaggt aaataaaata
     3901 tcacatttga ttaaatttta agttaatgaa tatatgtgta aatatttaat tataagttat
     3961 tataatttta catagtatca aacaatctaa tttgtattat ataagataat ctaattttag
     4021 actaaaataa tctaatataa agaaataaag aaaattcatt ctcagtataa gagatatcca
     4081 attttccatt gtacttatta acaatttctc taatattctc aataccatat ccgtgagaat
     4141 tactatcttt tttatctgaa ataaatagtt cttgttttct attgatagga tttaccttgt
     4201 tgtttgtcaa taaatagcta aaatactcct tctcacaacg tgcctttaat accacttttc
     4261 tatttgacaa atcaggaatc ttcaaagatg cttctatagc gttatctaaa gaatttgaaa
     4321 aaatagtaca taaatctata ggttctatac ccaagtgatt gtctatatct atattaaagt
     4381 gcacatcaac accattttct tccaaacttg tatgacgaag atttaaaatt gagttaagag
     4441 cttggttttt gcaaaactgt ttgccactaa gagtacctat acctattttt aactgattaa
     4501 aatacttttt agctccagca atatcttcaa tttctaaata cgattcaatc atttgaaagt
     4561 gattattcat atcatgtcgc attttgcgta tttgaatttg ttgattttct agtaagttat
     4621 agtatttttc ttttagatga tttgcttgtt tttctatctt catctttaca ttttcaatca
     4681 atggctgtaa aagaagtatc acaccgatat ttgccagaat tgctgacaag atgattagat
     4741 aagtgccata aggtaagttg cctaagataa tattcttatt actacccata gggattaaat
     4801 tagtaggtgg cagaataata gcaattaata ttgataaaaa tgaagatata cataccatat
     4861 caataaaaat ccatatttta tttgataagt attgttttat attgaccaat ctattcttta
     4921 ggaaaatatg tattaaaaac caaaataata atttaattag agcagaaatt atctggacta
     4981 ttgaaagtat taaaatatac tcttttgagt gtataagttc ctcatatata gggttgttta
     5041 taaaaagaaa attaagccca attataatag gataaaatat catgacaact gatattatag
     5101 gaattaattt gcttttgcta catattataa gtagtataaa atatccgaat agtgtaaaca
     5161 aaatatttac ggggtcggaa agccatatta tcatttgact aataatagag tagcccaaaa
     5221 tcaatatgat tttgaaaatc caatgattcc taaagtctat aaaataggaa gtcaacgtat
     5281 aaagaaaaaa ggctatgaaa atattgatta atattagaat aaaatttatg cttgtagaga
     5341 ttaaagaata agtgcccatt taatatacct ttctattaat taagattctg gaaactaagt
     5401 tttaaaaaat taaatcttaa aaattaaaat tctggaaatt aaatttcaaa gaattgattt
     5461 tgaaaaataa aattctagag attgaacttc aaaaaattga gttttaaaag attgaaattt
     5521 taaaaattaa gtttcaaaaa attaaatttg aaaaaaaact ctaaaaacta agcttcaaaa
     5581 aattaaattt tgaaagattg aaattctaga aactaagctt taaaaaatta agtttgaaaa
     5641 aacaaaactc taaaaactaa gcttcaaaaa attaaatttt gaaagattga aattctagaa
     5701 attaatcttc aaaaaattaa atttgaaaaa acaaaactct aaaaactaag ctttaaaaag
     5761 ttaagtttca aaaataaaat tctagagatt gaacttcaaa aattaaggtt ctaacatata
     5821 ccttgtaaat tttcctacaa cctcttgata ttttttacgg cttataggaa ttttttcatt
     5881 ctgaactttg gcataagttt gagttatact atctacatgg tttagattga caatatacct
     5941 ttgatgcgta cgtataaaat tagagggaag aacagtttcc atatcattta attttccgta
     6001 gtattctaat gttttatcaa aggtaactac agttaatttt cttagctcac ttttaaagta
     6061 gaggatatct tttgtattaa ttttacaaag attagttcca atctgaactg taataaagtt
     6121 ttctttccat tgttctaatt tttttagtgc ttcttttaat actttacata ttttttcagt
     6181 tttataaggt tttaagatgt agttcaaagc tcctacatca tatccatgaa atacatagtc
     6241 agaaaaacct gtgacaaaga tgattatagt atcctttgaa tgttttcgta tagtttttgc
     6301 tatgtcaacg ccattacttt ttccaagttc aatatctaaa aaaataatat ctatgtaata
     6361 attttcgtgt tctagattgt atactagact ttctccattt gaatattctt ttatttggta
     6421 ggggtagccc cacaaatcca tttctcttgt aatgatttta ttcagcatgt ttctttgttg
     6481 tttttcatca tcacaaatac aaatcgaagt caatttttta tctcctttca aattttatat
     6541 ttatatagtt aagtatataa tatattttgc tacctagata tataaaatga aataacaatt
     6601 atatccagat agcaaaataa aattttttat attagtatac ttacacttaa aactattcta
     6661 ttaaacttat tctgaagtgc taatgatttt cttattaaaa aatctaacaa tctttcttat
     6721 tataaaatac aaatgctttt attattataa aaagtaatga ttttattact ttaaaaatct
     6781 aataaccttt cttattataa aacaccaatg attttattac tttaaaaatc taataacctt
     6841 ttttattata aaacaccaat gattttatta ctttaaaaat ctaataacct tttttattat
     6901 aaaataccaa taattttttt gaatttctta taagttaata gatatataag gtacatataa
     6961 accccacaaa tccctataaa acctaagttt atcaaaagag cattgacctc actattgacg
     7021 attctaccat cattatttaa cataatcata aaattaaaca gataaattaa aaaacttcct
     7081 gcaataagag ggtatgaaaa tactttcttt aattgatttc taatacagaa ctttatataa
     7141 tcattgtttg ctcctaatcg atttaaatcc ataaagacct gcttgtgatt tatagctata
     7201 gtaacacccc ttgtatatgc aatgattcct actgctgtaa aacatatgat tgccacatat
     7261 atgaataaca ttaagaagac tgccatgttt tttatcatat cttggctttg taaaatttta
     7321 aagttaggat agtatttcca attaagatac aactgattgt tgtttgggtc tagttttaaa
     7381 tgaccttcac cacttggata ttcttcatcc ataaaatatt ttcttccagt tgattcataa
     7441 cgttttttta cgtattcatc ataaccactg aacatgccca tttccttaga tgttcttttt
     7501 ataatttctt tctttaagtc attggcaaaa gcataggtat ctttatctac attaaatagt
     7561 atagaattat tgtaattttt tatggataaa tctttagtaa atgatttata atcctcatca
     7621 ttaaggacat aggcgttcat acttctattt tgaaaaaaag aaccattaaa tattattttt
     7681 ccagcatatc taaaggggat ttctttttct gtgactgggc ttgatataaa tttggtatat
     7741 ttataatctt gattttcatt tcctttattt acaacagcaa gatattcacc attttttata
     7801 gttattggtt tgccaattag cttggaaaaa tctttagaat taaagaacat atcataggag
     7861 ctttttttca tatatacctt ttcgatagtt ccatctttat gatatattga ttctacacca
     7921 tcaacaatta attctataga aggaatttcc atatagtttt gaatttttat attgtgttta
     7981 tctgctaatt gttcaatatc tttttttgat acctgtttat ctctttgatt gtaggtaaaa
     8041 gtataatcta tagggttatt tttaagagta tcatagatac ctgtaaccat attaggaaca
     8101 tagaatacag caaataatgc tcctgcaatc aaaaatgaaa taacacacat gttttttact
     8161 gtttgtcttc ccataaatct catcatgcta gttgatatga tgtttttata gtatttctct
     8221 ggatgttttc ctcttttagc atgtacaact atgtatgtca taatcatata tattccaata
     8281 agagagagta gataagtaaa gctccatata gatggtagtt tataatttaa tttgtttata
     8341 gttagtgaag gtacgagata tcctagaaaa ataccgagta taataaaaat tatacctaat
     8401 ataccatacc agtcctttac atcctgtatt ggttcagata ttctctggtc atttaatata
     8461 tcaattatat ttgtacgatt aataaatttt acagaaagta taaatatgca taatgtcaca
     8521 aatacactaa atataaatcc atatatgaat ccttgagttc caaaatgata tgtcatttct
     8581 ctggtatcaa taatcactaa ttgaaatatt ttccatatac caaaagatac aggaatactt
     8641 aatataagac ctaaaaaaca gcatactatt gaaattaaca atatctctga aaatagaagt
     8701 ttttttaatt tcttcttatc tgttcctaga gccatgaaaa taccaatttc cttgctttta
     8761 aattttaaaa agagggaaga agcgtatgta gtaaagacag cgcatcctaa tatagcaact
     8821 gagaatatca ttgtagcctg ttttctgcta tctccaccag ttggaagtat gttttgtatt
     8881 gttgggctaa aataaattag agcatatgaa gttactaata ccacagaaag tattatacaa
     8941 aagaataaag ttgtatagtt cttccaatta taggctcgaa gtttactgta taatttatta
     9001 attgtcatct tgagcgcctc ccatttcttt taaaacttct agtaattcat ctaggaattt
     9061 atgtcttgaa tttgatttta caacttcttt ataaattatt ccatctttaa gcacaataac
     9121 tcggtcacag aagcttgctg caaagctatc gtgtgtaacc atgagtatag tagcatctaa
     9181 ttcttgcttt gcttttaaaa atgattcaat gactgtacga caagacttac tatcaaggtt
     9241 accagttggt tcatctgcta atattaaatc tgggttgttc atgagtgctc ttgctactgc
     9301 tgtacgctgt ttttctccac cagatatttc ggcagggtat ttttttctga tatgttcaat
     9361 accaaatagc tcacatagat taattgcacg gttttccatt tgtaagactt gactaccttt
     9421 gataatttgt ggaacacata tattttcaaa gacactaaga ccatcaaata gcatgaagtc
     9481 ttggaataca aatcctagtt gttgatttct aacttctgaa agttcctttt cttttaaatt
     9541 tcttatatta ttatttccaa gaattatttc cccattatca attgggataa aacatgaaat
     9601 acaatttaaa agagtagttt ttccacttcc tgatgaaccc atgattgcga caaattctcc
     9661 tttgttgatt tcaaaagaaa tattttttaa tacaggatat gttttactgc ctgttttata
     9721 tgatttacat aattggttta ctttaagcat atatatcatc ctcactttca tttatcttgt
     9781 aagtcaatga tagcatttga aaggggagga gggatatgag ctatattgta atagttggat
     9841 gtttttttgt aatgtttgaa aatatattgt ttggatagtg tgagaggtta ttattatagt
     9901 taaattgatt atattattgg aggatttaga gggttatttt taggtattaa ttgttgtgct
     9961 aaagtaatat gatgtggaac attgaaggtg tagttagaaa agaagtatat agtaaaagta
    10021 aaaaggttat agaataacga atgttgtatt gaaaaaaatg atgtaaataa tgtatagtag
    10081 ggttaaaaag aaaaaaagaa ttatagagca gtaagattat ttaatagaat gtattgtaaa
    10141 taatttgaaa ggatttaggg gctattaaca caatgtaatt gagaaaatat attggagttt
    10201 tggaaataaa taggttgtta gaaacaattg aaatgtataa taaaaaggtt aaaaagtatt
    10261 attagtatag gtatgataga taattttaga aagtggaagt attttagact atgctgaaaa
    10321 gtgattgata tgattttgag atattaaaat attactatat tatagtaaag aagttaaaat
    10381 aataaaatgt tgtaataata aaggtttgta gtataataaa gaactgtaat aaataagact
    10441 ttgcaatgta atagaaatgc tgtaataata aaagtctgta gtataataaa gaactgtaat
    10501 aaataagact ttgcaatgta atagaaatgc tgtaataata aaggtctgta gtatagcaaa
    10561 gaactgtaat aaataagaga ttgtaataat aaaagtctgt agtgtaataa agaactgtaa
    10621 taaataagac tttacaatgt aatagaaatg ctgtaataat aaaggtctgt agtataataa
    10681 agaactgtaa taaataagac tttacaatat aatagaaatg ttgcaataac aaaacaccat
    10741 aataaataag agtttgcaat ataatagaaa cactgcaata aataagagat ttcaatataa
    10801 taaaagtctg taatataaca aaatcctata ataaataaga ttttacaata taataaaaat
    10861 cctataataa ataggactct gtaatataat aaaatgctgt aacaacaaaa cactataata
    10921 aataagaccc tgtaatataa taaaaatact ataatatagt aaaaatcatg caataataaa
    10981 aatctataat aataaacctc agcataacaa agacattaat ttcttactaa aaaggccacc
    11041 acaattaaca gtgaaaaagc aattgaaagt attgaaaaag taaaatgaga attagagtca
    11101 ttattacgat tattaagttt tatccataaa ccacatataa ttgtacacaa caataaaatt
    11161 gctgatatta ctcctataaa tgtaaaaaac attaaaattc ctccccctta tttaatgcaa
    11221 gtatttttag tcaatgagaa tattttcaaa cgttaccata aaataaaaaa atgtacataa
    11281 aaaattaata tagtattatt ttgtaatatc taccaataat aaatctaatt gaaaatctat
    11341 taaaccattt ctctgttcaa tattaagaat atcaatacca ctatacttga aaaaagcatt
    11401 agaacgaaga aaaagcaact gaataaatga agttatttga tacgcaatag ttctgtattc
    11461 agcttcagtt tttttgttat tctgattttc atagtgagcc ttaattaaag gtagtatctc
    11521 aaatggataa acaatttctt cctgtatcaa tatatagggt acagaaatct ttataaattg
    11581 actatgttca cctataaaat caaaaaatgc aattagtatt tcccttaatt gctgtttagg
    11641 tgctaaattt ttagtatcat gtgtagcctt atattcatcc atatgacgct ttaaaaattt
    11701 tttaatagaa atattaatta actcctcttt agatttaaaa taataattaa tcatagctaa
    11761 attgacattt gctttagcta caatttctct agccgtaatg cttgaaacat ctctatgtga
    11821 agatagtaac tggattgtgg cattaattaa ttgttccttt gttgaatctg ctttcataat
    11881 ttttcccctt aaaagtttcc ccataaaaaa attaaacatg tttaacacac gtttagatac
    11941 tatcatgaaa attttgggat gtcaatgggt gattagtact taagtattta agtactaatc
    12001 tattagactt ttataagggg gatttgaatt tctgtaagat aattttcagg atttatttca
    12061 ttatgttcac ctttatgtcc gatttgtcta tttatacctg atatttgata atcactattt
    12121 ttatctaacc aataacagaa cgattcatat gcaccagcta tattttcata tggaccataa
    12181 accatagtac atgccatcat atcaatttct tctgtctcac gatatataaa tccagatttg
    12241 ttctttccaa tcttctttac aaccattcca acttcaatat ctacaccatt atctttgact
    12301 tcttcatcat ggtaaaaagc tatgttattg ttggattgac gtgatacttc tatatgttct
    12361 tctttgataa atttagatag cttttcccag agtatacctt cagattggta gtctggaatt
    12421 atctctctaa gtgatatgat tttataactt ggaatctttt taaagacaac attgtaatga
    12481 atttcatctt tatcacagtt tatagcttct ataaatttat caattttatt tattctttgt
    12541 tgttcctgat ttatttcctt ttgtatttca ttcttttttc tattcaattc tttaattaca
    12601 aattcatcat tccaattatg tacgatattt gctatttctg caacgctaaa ttttgaatct
    12661 ctcaataata caattctttg tagtattgaa atctgttcaa ctgagtataa tctatgacct
    12721 gtatatttgt ctatttctgc aggttttaaa ataccaagtt catcataata acgcaacata
    12781 cgaatagaaa tttgtgttag ttttgaaacc tctcctattt taaacatgaa aatatgacct
    12841 ccttttcact tataatcagt atatattttg tttttatata cttcaagcgt ttgtggaaat
    12901 acaattattt tccagatgtt gcaataaatt atagagagta aattatattt aagtagtaat
    12961 cgtatcaaat catagattat cttaatttat aattcatatt aaaattacca gtctaactca
    13021 aattcaaaat catccgactt tatctgttca atttcagaat ttaccttctg tttaaattta
    13081 ttagaagaaa tcatatatac aagaaatatt aaaccaaata ttatttgtac atattgagct
    13141 attacacata atttaatagg gtagtgtaga agtaattgaa tgttgaaaaa atagtacatc
    13201 atatgaacta acccagctga taaaatgctt ctacttgtat tgatatatac aaaattaatt
    13261 ataaagttta aaagtacaat gtttggtata aataaaaaag catcaaatag ggagtattgt
    13321 gccaaattat atggtatttg attaggtgta aaatacgacc ctagatacca gattccacaa
    13381 acaagcccta aaataattga agagcctata aatccaaatc taactaataa tttgtcaatg
    13441 gcatatcctc tccatccagc ttcttgacta agtatactca atataaaact tgctaatagc
    13501 atataagcta ttttagaagg tctaaacact gctatgtgta tccaatctat atcagaagtt
    13561 tttacattaa agtaatttcc gattattaac gaagtaataa aagttaaagc aaaaaataat
    13621 attgttaata gtatccattt tattctaatt tctttaaagc ttaggtatct ataaataaaa
    13681 tcttgttttg cactttgtgg atagattgta gaaataaaaa atagacctac aatagctggt
    13741 gatgtatatg caagataaaa aatgatttct ccaagtattg tatttgtaat tccgagcaac
    13801 gcaggtgtaa gactgaatat ccagttcaat actagcgtaa atgtaaagaa atagattaag
    13861 tgtttgtttg tattaaaggg ggtgttatat agttgcattt tttcactatc cttccgtttt
    13921 ataatgaagt tttaattttt attaattgtt tatttatttt tatatgtatt aagttatcgc
    13981 ttgatgttag ttattgccta taataatatc ctatttttta tattttgatt aattattttt
    14041 acactaaata taatta
//
LOCUS       DAMJVG010000094        13804 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.097, whole genome shotgun sequence.
ACCESSION   DAMJVG010000094 DAMJVG010000000
VERSION     DAMJVG010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13804)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13804)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13804
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.097"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            76..522
                     /locus_tag="PC512_003165"
     CDS             76..522
                     /locus_tag="PC512_003165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442894.1"
                     /translation="MLTYLMKRQMHKKDDGMSKPMMITGAVITGVGAYAVYKMVKSHK
                     SNSQMVNTNYYGNSDYDDYKYDEFDYDCDCRDTKQDYEYEELKKKVKEFNSRRINCEN
                     CPHVSQEEMMQYVNSVKDVKEEIDLHEDAKKDNIYKEDEYKKYEEE"
     gene            786..1511
                     /locus_tag="PC512_003166"
     CDS             786..1511
                     /locus_tag="PC512_003166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2442895.1"
                     /translation="MKRKEIVMLKLLIVEDDSTISFGIKYALEQEGFSIDISKDLSSG
                     KEMISSNEYSMILLDVTLPDGTGYELCQYIRGFSQVPIIFLTACDEEVNIVMGLDIGG
                     DDYITKPFRIRELISRIKAVLRRKGNTSEENKKILKFGDLSIYTLEARVYKNDKEIFL
                     TSVEYKLLLILIQNKNTVLSRTQILEKLWDVTYDFVNDNTLTVYIKRLREKIGDDLCE
                     PIYIETVRGIGYKWIGSENSVSI"
     gene            1498..2742
                     /locus_tag="PC512_003167"
     CDS             1498..2742
                     /locus_tag="PC512_003167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2442896.1"
                     /translation="MFLYNPEVKKFLSKYVTLMFIVIIISIGFSIINVSLTKEMVVRN
                     NQAIIGTLSSKYPNLESQIVDIITQGKSMENIDYGQKILIKYNYDKSIRINSEPIISK
                     LVLETIKINIILVCIIFILIFVLVVRYFKSIYNDLSDMTKYVYYSSEGKPFDMKNKNQ
                     EGQIGLLKTELLKMTTILNEKVELLKREKIFLNNTISDISHQLKTPMTSLIMLNDLLY
                     NDVPYEVKIDFLNKIKNQLNRMDWLIKSMLKLSKVEAKVINFKKDKVKFSELIHRAML
                     SMKIPMEIKNQKLTIEGNDNVSYIGDIDWSVEALVNIIKNCVEHTPEFGNIIITYKEN
                     PLFSELIIKDEGEGIDKKDIPHVFKRFYRGRSSSKEDSVGIGLAMSKSIIESQNGDIY
                     VNSEKGQGTEFHIIFHKMYDSD"
     gene            2822..3499
                     /locus_tag="PC512_003168"
     CDS             2822..3499
                     /locus_tag="PC512_003168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003517588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2442897.1"
                     /translation="MEILRVENLTKSYGKNETKVDAIKNVSLSVEKGTFIAITGPSGS
                     GKSTLLHLLGGVDRPTSGKVYINDVDIYNLKTKDLAIFRRRNIGLIYQFYNLIPVLNV
                     KENILLPAELDNRDIDREYFDDLMKTLGLIDREKHLPNQLSGGQQQRTSIGRALINRP
                     SIILADEPTGNLDSKNSKEILELLKLSVKKYNQTLIMITHDKNMALQADRIISIEDGI
                     IKSDEVM"
     gene            3500..6061
                     /locus_tag="PC512_003169"
     CDS             3500..6061
                     /locus_tag="PC512_003169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2442898.1"
                     /translation="MNLYTLLTIRYLKQNKRRTIVTIIGIILSTALICGIGNIFESFM
                     DYQMRETIKNDGSFHVTFYDVNRKNVEYVTKSAEIEKHAFTKQLGYSKLENSENAILS
                     IKQYDKNAINGYKVSIKEGRFPAKEGEIVLSESIINLIDDKLKIGDKITLKVGDMFDS
                     SKKKIDSMTFHEGDYIANEKDRTFKVVGIIEKPGFERYNGIATAIAYFNPMNNYNDTI
                     NVSVAVRNPKDVYKISNKISKNIYSNKDKEAVSDMIKYNEHLLRLQGASKYSNINNSI
                     KSIIIAVTILVIICTIATVYNSFSISINERKKQFGILNSIGATSSQIKRLVFIEGIII
                     SLIGIPIGLISGTVAIDLLFKIINKYFTESVVTKMSLQIVYNPIITIVSIIIVLLTIF
                     ISILLPAISASNISHLNVIKNTGEYKVGKIKSSRLIKMIFKTEGVLAYKNIRRNRKKF
                     IITLFSLMVSIIIFISFSGFTLLLLRGEEIRNSQRKYDLYLTAKNTARSVEDTISELE
                     DIDGIKNFELATGQYVSIRVSENKINKSKEDLIRKYYQKYKIGDSYEYDFSNNELIFP
                     GDFAVKNKINNLVQGSFNKERAIEENGVILVRKSAFEENGKKGVVELTNYKVGDTVNC
                     EYLDENALSKKVKVKILAITDEERLGLGYQNMGLQFITYDEVAKNLNLKLSKSLIFID
                     SGGSIKTKKEIEALANKNNFNFYDESASNESEKQDLKVIKIFVYGFIVVISLVSVTNI
                     LNTVSTSINLRKRELAVIQSIGVTPKGFRKMIYLESFIYGILSLLFGIPISIGIILIM
                     NKLISGVIEFSPIIPWTAIVICIVSVFIITFIAGYIPMSKLNKENIIDNIRRESI"
     gene            6252..7526
                     /locus_tag="PC512_003170"
     CDS             6252..7526
                     /locus_tag="PC512_003170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HDF2442899.1"
                     /translation="MITISHITAKNMYKSLEERINKFPQGAPPSDTLYKILNVLYTEQ
                     EAKLVAQLPIKPFRVKTAAKIWSVSESEAYRVLDKLASKALILDIEDNKGKKYIMPPP
                     MAGFFEFAMMRTRHDIDQKLLAELYYQYMNVEEDFIKDLFYSTETKLGRVYVQEEVLT
                     NDNEVSILDYERATHIIDESTHIGISMCYCRHRMQHVGKACDAPMDICMTFDNVANSL
                     INNKFARRVDKIECKELLHQAYEHNLVQCGENVRKGVTFICNCCGCCCEAMVAAKRFG
                     NLHPVQTTSFIPNINHENCVKCGKCITACPIDAISKVKEDGKEYIKIDEDRCLGCGVC
                     VRNCHKNSIMLLKRDEKIITPANSVHRAVLMAIEKGQLQNLIFDNNALASHRAMGAIL
                     SAILKLEPAKKILASKQLKSVYLDKLLSMNDK"
     gene            complement(7687..10728)
                     /locus_tag="PC512_003171"
     CDS             complement(7687..10728)
                     /locus_tag="PC512_003171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp20"
                     /protein_id="HDF2442900.1"
                     /translation="MFKQRLSKLLSSTLVLSMLFTAAPNITFADNTKDNSEKYQSSDI
                     ELHDYSKNAESYTKTKALAKEKIQTLLSKYGAVSAQYALIDNGKIEISGNGGVYSKQD
                     NKNLNKDNMYSIASISKMFTTTAVMKLVDDGKLNLDTPVVKYIPEFKMADDRYKEITP
                     RMLLNHSSGLMGSSFKNTILLADNDSYGHDNFLKELQKQRLKAKPGAFSVYCNDGFTL
                     AEILVERVSGMSFTNFLDKYINNPLNLQNTKTPENSFDSSKLAKAYVPYWEDAVPQDN
                     LNAIGAGGLYSSAENLCTFAQTFMKNSNGILSPASVKAMENKEYLNGLWPEGEDSILG
                     YGLGWDCVNTYPFNQYNLKALTKGGDSLLFHSNLIVLPDENMAVAVLSSGGSSQLNEI
                     IGQEILLSALKEKGKIKEIKPDKTFSKPQQVKMPSSLKENSGLYASSNMIKVDVNDNG
                     TLTVSSPYIENGPEDKYVYIGQDRFVSEKGNSCLKFVKEKNNITYLNMSSYDDVPGLG
                     QTASLYYVAQKVDDNNISNSVKEVWKKRSGKGYYLVDEKYTSQSYMFGSVKASFSLSD
                     ETPGYIVNTKIMDENNSNAFIEIPGVIGRDLSDIKLHKENGTEYLSFGTLTYVSEDSI
                     TNLPAEKSFTCELESNGYAKWYKIGDDIANKKIEVNLPQNSAFAVYDDKGVPVNYSLV
                     TKNNRVRLPKGGVIVFLGSPNARFEVTYQDEVNASALTGTDRYETSIKISQAGWENAE
                     NAVLINDSAIADALAATPFAYKKNAPILLTGSSQINEKTLAELKRLKVKNVYVVGGEA
                     SINEKSLDTIKSNNISVSRISGSDRYQTSMNIAKELNNISNISKISVVNGEKGLADAV
                     SIGAVSAQNDMPIILTNENSNITEINNLFKNKKIDKSYVIGGEYTVSKNIESKLQNPQ
                     RISGSTRNETNAKVIKEFYKDSKIDNLYVAKNGMNKQDDLIDGLSVGVLAGKTKSPVM
                     LVGNSLDYNQKELFKTMRFKSVTQIGGNGNENSFKQIKEIA"
     gene            10935..11234
                     /locus_tag="PC512_003172"
     CDS             10935..11234
                     /locus_tag="PC512_003172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HDF2442901.1"
                     /translation="MYKNINKKQLKEMMKNEKDVLLLDVRTKDEFKEYKIENAINISL
                     QELINNIDEIYDYKDKKVVVYCRSGHRSVTACNLLAEEGFEHLYNLNSGIIDYMS"
     gene            complement(11472..13700)
                     /locus_tag="PC512_003173"
     CDS             complement(11472..13700)
                     /locus_tag="PC512_003173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HDF2442902.1"
                     /translation="MRHLKKTNSLKEILNWNNIKNLRPSKGLKNILEIFKSDLKDIRG
                     NYAVLVIVLGLAFLPSLYAWFNIKASWDPYGSTANMLVAVTNEDKGNEIAGQKINVGD
                     QLIEQLKDNKSLGWQFVDEKTALEGVKKGTYYASLKIPKNFTKDLTSLITDDVKKGEI
                     IYTVNEKINAVAPKITDKGASTIQLQVNQTIVKTVSEIVLGISNGVGAGIEHSLPKLT
                     KVENSLIDLQKRFDHINKTVDLASDATSKLSDTVKDIKSDLPTIKKTLNDTKLLSSDL
                     KKFLEDTNDNLDELSPLIKSDLNLMVDLSSSASSLTLNLIDAVNSGSEDVPKLIDNLS
                     EKLSNLQSLNDTLVDFLTKLNQLTSNNRLDDVIDNLEDSSNKIDSSISTLNDIKNKVI
                     SGQQPSISALNNVLSLSNGIGRINLNILNNFDSKISKPINSIFANSIKVANDIITVLD
                     KAEAKLPKVEEILTTSLKLSGNAQESISLIRERLPLAKGMLDDLIDTLSKISNGEDMK
                     KLVSLLESDILTKSNFLKEPVEVKTEKLYPIENYGSAMTPFYSVLSTWVGILLISALL
                     STSVHGNYKPYEIYFGRGLTFLSIALVQGFIIGTGDILLLGVTAKHPILLIVLLMFTS
                     MVFNFIVYSLVSVFGNVGKAIAIVLLVVQIGSSGGTFPIQVTPTFFQRINPIMPFTYA
                     IGATREAVGGIYAPNLTKDILVLLLFMILSICLNVLLKGPINRVIKPFNDKFGDSNLT
                     GH"
BASE COUNT         5250 a         1657 c         2100 g         4797 t
ORIGIN      
        1 aaataacata atttttatta aaataataca gatactattt atagatagaa ataaaaatta
       61 gaaaggagaa aaaatatgtt aacatattta atgaaaagac aaatgcataa aaaagatgat
      121 ggaatgagta aaccaatgat gattacagga gctgtaatta caggtgtagg agcatatgct
      181 gtatataaaa tggtaaaaag ccataaatct aattctcaaa tggtcaatac aaattattat
      241 ggaaatagcg attatgatga ttataaatat gacgaatttg attatgactg tgattgtaga
      301 gacacaaaac aagattatga atatgaagaa ttaaaaaaaa aagtaaaaga atttaattca
      361 agaagaataa attgtgaaaa ttgtccacat gtttctcaag aagaaatgat gcaatatgta
      421 aatagtgtta aagatgtaaa ggaagagatt gatttacatg aagatgctaa aaaagataat
      481 atttacaaag aagatgaata caaaaaatat gaagaagaat aagtaatatt ttgtataact
      541 gaacaaatag taatgtcaaa ttatttaata tctagtttta atatgtaagt tgtaacttaa
      601 cttgaaagaa tcagtatcat tctttagata gttaagtaac aacttacatt ttatttttat
      661 aaattttaat agttctttgt gactattttg taattttaga aatattttag tatccagggt
      721 aattgtgtat aataaaactt gtatagatag atagtatgaa attaagcaga tagtttaaaa
      781 ttaaaatgaa aagaaaggaa atagttatgt taaagttgtt gatagttgaa gatgatagta
      841 ctatatcttt tggaataaag tatgctttag aacaagaagg atttagtata gatatatcaa
      901 aggatttatc tagtggaaaa gaaatgattt cttctaatga atatagcatg atactgttgg
      961 atgttacatt gccagatgga actggttatg agctttgtca atatataaga ggattctctc
     1021 aggttcctat aatattcttg actgcttgtg atgaagaagt aaatattgta atgggtctcg
     1081 atataggtgg agatgattat ataacaaaac cttttagaat tagagaatta atatccagaa
     1141 taaaagctgt tttaagaaga aaaggtaata cttcagaaga aaataagaaa atacttaaat
     1201 ttggagattt aagtatatat acattagaag ctagagtata taaaaatgat aaagaaatat
     1261 ttctgacatc agttgaatat aaacttcttt taattcttat acagaataaa aatactgttt
     1321 taagtagaac tcaaatattg gaaaaacttt gggatgtaac ttatgatttt gtaaacgaca
     1381 atactctaac tgtttatata aaaaggctta gagaaaaaat aggtgatgat ttatgtgaac
     1441 caatctacat agaaactgta agggggattg gttataaatg gataggaagt gaaaatagtg
     1501 tttctatata atccagaagt gaagaagttt ttaagtaagt atgttacttt gatgtttatt
     1561 gttatcataa tatctattgg atttagcata atcaacgtgt ccttaactaa agagatggtt
     1621 gtaagaaata atcaggctat aataggaact ttatcaagca agtatccaaa cttggaaagt
     1681 cagatagtag acataataac tcaagggaag tctatggaga acatagatta tggtcagaaa
     1741 atattaatta agtataatta tgataaatct attaggataa actctgagcc tattatttct
     1801 aaattagttt tagagactat caaaataaat ataatattag tatgtataat atttattttg
     1861 atatttgtgt tggttgttag atattttaag tcaatttaca atgatttatc agatatgact
     1921 aagtatgttt actatagttc agagggtaag ccatttgata tgaaaaacaa gaatcaagaa
     1981 gggcagatag gtcttctaaa aactgaactc ttaaagatga caacaattct taatgaaaag
     2041 gttgaacttt taaaaagaga aaagatattt ttaaacaata caatttccga tatatcacat
     2101 caattaaaaa ctcctatgac ttctttaata atgttgaatg atttattata taatgatgta
     2161 ccatacgaag taaaaatcga ttttttaaat aagataaaaa atcaattaaa tagaatggat
     2221 tggttgatta aaagcatgct taaattatca aaggtagaag caaaagtgat aaattttaaa
     2281 aaagataagg taaaatttag tgaactcata catagagcaa tgctatctat gaaaatacct
     2341 atggagatta aaaatcaaaa actgactata gagggaaatg ataatgtatc ttatattggt
     2401 gatattgatt ggtccgtgga agcattagtg aatataatca aaaattgtgt agaacatact
     2461 cctgaatttg gaaatataat tataacctat aaagaaaatc cattattttc tgaactaata
     2521 ataaaagatg agggtgaagg tatagataaa aaagatatac cacatgtatt taaacgattc
     2581 tatagaggaa gaagtagttc aaaagaagat agtgtaggaa taggtcttgc aatgtcaaaa
     2641 tctataatag aaagccaaaa tggcgatata tatgtaaaca gcgaaaaagg tcagggtaca
     2701 gaatttcata taatatttca taaaatgtat gatagtgact aatctgtaat atttaattca
     2761 ctttatagta atagccaaaa cctaatatat gaagtataga atataaatat tggaggtagt
     2821 tatggaaatt ttaagagtag aaaatctaac taaaagttat ggtaaaaatg aaacaaaagt
     2881 tgatgctata aaaaatgtaa gtttatcagt tgaaaaagga acgtttatag caataacagg
     2941 tccaagtgga agtggtaaaa gtaccttatt acatttatta ggaggagttg acagaccaac
     3001 tagtggtaag gtttatataa atgatgttga tatatataat ttaaaaacta aggatttggc
     3061 gatatttaga agaagaaata taggtcttat atatcaattt tacaacttaa ttccagtctt
     3121 aaatgtgaag gaaaacatat tgcttccagc agagcttgac aatagagata ttgatagaga
     3181 atattttgat gatttaatga aaacattagg tctaattgat agagaaaagc accttccaaa
     3241 ccaattatca ggaggtcaac aacagagaac ctctatagga cgtgcattaa ttaatagacc
     3301 ttctataata ttagcagatg agccaacagg taatttagat agtaaaaatt caaaggaaat
     3361 attagaattg ttaaaattgt cagtaaaaaa atacaaccag acactaataa tgataactca
     3421 tgacaaaaat atggcacttc aagctgatag aattataagc atagaagatg gaatcataaa
     3481 aagtgatgag gtgatgtaga tgaatttata tacattacta accattagat acttaaaaca
     3541 aaataaaaga agaaccattg taaccataat cggtataata ctttcaacag ctttaatttg
     3601 tggtatagga aatatatttg aaagttttat ggattatcaa atgagagaaa ctataaagaa
     3661 tgatggaagt ttccatgtta cattttatga tgtaaataga aaaaatgtgg aatatgtaac
     3721 gaaatcagct gaaatagaaa aacatgcatt taccaaacaa cttggatatt ctaaattaga
     3781 aaatagtgaa aatgctatat taagtataaa gcaatatgat aaaaatgcaa taaatggata
     3841 taaagtttct ataaaagaag gtagatttcc agctaaggaa ggagaaattg ttctaagtga
     3901 aagtattatt aatcttatag atgataagtt aaaaatagga gataagataa ctttaaaagt
     3961 aggggatatg tttgactcaa gcaagaaaaa gattgatagt atgacatttc atgaaggtga
     4021 ttatatagca aatgaaaaag atagaacttt taaagttgtt ggtataattg aaaaacctgg
     4081 gtttgaacgt tataatggaa ttgcaacagc tatagcctac tttaatccta tgaataatta
     4141 caatgataca attaatgtat cagtagcagt aagaaatcct aaagatgtgt ataagataag
     4201 taataaaata agtaaaaata tatattcaaa taaagataaa gaagcagttt ctgatatgat
     4261 aaaatacaat gaacatttat tgaggttaca aggtgctagt aagtattcaa atataaataa
     4321 ctctataaag tctataatta tagcagtaac tattttagta atcatatgta caattgctac
     4381 agtgtacaat tcctttagta tttctataaa tgaacgaaaa aaacagtttg ggatattaaa
     4441 ttctataggt gctacatcta gtcaaattaa aagattagtt tttatagaag gtattataat
     4501 tagtttaatt ggtataccaa taggactaat atctggaaca gtagctatag acctattgtt
     4561 taaaattata aataagtatt ttactgaatc ggttgttact aagatgagtt tgcagatagt
     4621 gtataatcca ataataacta ttgttagtat aataatagtt ttgcttacaa tctttatatc
     4681 aattctacta cctgcaatat cggcttctaa tatttctcac cttaatgtga ttaaaaatac
     4741 tggagagtat aaagtgggca aaatcaaaag ctcaagactt attaaaatga tttttaaaac
     4801 tgaaggagta cttgcatata aaaatattag gagaaataga aaaaaattta taataactct
     4861 tttttcttta atggtaagta taataatatt tatatctttt agtggcttta cattactttt
     4921 actaagaggt gaagaaatta gaaattctca aagaaaatat gatttgtatt taactgcaaa
     4981 gaacacagct aggtctgtag aggatactat aagtgaacta gaagatattg atgggataaa
     5041 aaactttgaa ttggcaacag gacaatatgt gtctataaga gtaagtgaaa ataaaataaa
     5101 taaatccaag gaagatttaa tcaggaaata ttatcaaaaa tataagattg gagatagtta
     5161 tgaatatgat ttcagtaata atgaattaat ttttccagga gattttgcag taaaaaacaa
     5221 aataaataac ttagtacagg gctcttttaa taaagagaga gcaattgaag aaaatggtgt
     5281 tatattagtt agaaaaagtg catttgaaga aaatgggaag aaaggtgtag tagaacttac
     5341 caactataaa gtaggagata cagtaaattg tgaatatctt gatgaaaatg ccttaagtaa
     5401 aaaagtaaag gtcaagattc ttgctataac tgacgaagaa cgtctaggtc ttggttatca
     5461 aaatatgggg ttacaattta taacttatga tgaagttgct aaaaatttaa atttaaaatt
     5521 aagtaaaagc cttatattta ttgattcagg aggaagcatt aagactaaga aggaaataga
     5581 agctttggca aataaaaata attttaactt ttatgatgaa agtgcaagca atgaaagtga
     5641 aaaacaagat ttaaaggtta ttaaaatatt tgtatatggt tttatagtag tgatatcttt
     5701 agtgagtgtt acaaatattc taaatacagt aagtacaagt ataaatctaa gaaaaagaga
     5761 acttgcagta atacaatcta taggggttac tcctaaagga tttaggaaaa tgatatattt
     5821 agaaagtttt atatatggta tactgtcatt gttgtttgga ataccaatta gtattggtat
     5881 aattctaatt atgaataaac ttatttcagg tgtaattgaa ttttctccga ttataccgtg
     5941 gacagccata gttatctgta tagtaagtgt ttttataata acttttatag cagggtatat
     6001 accaatgagt aaattaaata aagaaaatat aatagataat ataagaagag aaagtatata
     6061 gatataaaaa taattcttaa ctatataaaa tattattata tcacttaaat gattttttat
     6121 ttatataaga aatctaataa taaattacta gaggtattta actatttaga aagaattggt
     6181 attatataaa gtaagagaat atataataag aaagaatatt tgattttatt ggaaaacaaa
     6241 agaaaaagaa ggtgattact atttctcata taactgcgaa gaatatgtat aaaagtttag
     6301 aggaaagaat aaacaagttt ccacaaggtg ctccaccatc tgatacatta tacaaaatac
     6361 taaatgtact atatacagaa caagaagcga agttagttgc tcagcttcca ataaagcctt
     6421 tcagagtaaa aacagcagct aaaatttgga gtgtaagtga aagtgaagca tatagagtat
     6481 tggataaact tgctagtaag gctctgatac tagatataga agataataaa gggaagaaat
     6541 atataatgcc tcctccaatg gctggttttt ttgagtttgc catgatgaga acgagacacg
     6601 atatagacca aaaacttttg gcagagcttt actatcaata tatgaatgta gaagaagatt
     6661 ttatcaaaga tttattttat tcaacagaaa cgaagcttgg aagagtatac gttcaagagg
     6721 aagttttaac taatgataat gaggttagta ttttagatta tgaaagggct actcatataa
     6781 ttgatgaatc aactcatata ggtataagta tgtgttactg tagacataga atgcaacatg
     6841 ttggaaaagc ttgtgatgct cctatggata tatgtatgac gtttgacaat gtagcaaatt
     6901 ctttaataaa taataaattt gcaagacgtg tggataaaat agaatgtaaa gaactacttc
     6961 atcaagcata tgaacataac ttagttcaat gtggagaaaa tgttaggaaa ggggttacgt
     7021 ttatatgtaa ttgctgtgga tgttgctgtg aagcaatggt agcagctaaa agatttggaa
     7081 atcttcatcc agtacagaca acaagtttta taccaaatat aaaccatgaa aattgtgtaa
     7141 agtgtggtaa atgtataact gcatgtccaa tagatgcgat aagcaaggtt aaggaagatg
     7201 gtaaagaata tataaaaatt gatgaggata gatgtctagg ttgtggagtt tgtgttagaa
     7261 attgccataa aaatagcatt atgttattaa agagagatga aaaaataata actccagcaa
     7321 attcagtaca tagagcagtt cttatggcaa ttgaaaaagg gcagttacaa aatttaattt
     7381 ttgataataa tgctctggct agtcatagag ctatgggagc tatactgtca gctatattaa
     7441 agcttgaacc agctaaaaag attttagcca gtaaacaatt aaagtcagta tatttagata
     7501 aattgttaag tatgaatgat aaatagaaac taacttaaaa aaggcaaagt tttagactta
     7561 tctatatctt aataaactta tcatttaata tttaaattta atttttacac atataaaact
     7621 tataacttaa ataaaaaaag gctatattca attaatatta cttgaataca gcctttttta
     7681 gttatgttaa gctatttctt ttatttgctt aaatgagttt tcatttccat ttccaccaat
     7741 ttgtgttaca gatttaaatc tcatagtttt aaatagttct ttttgattat aatctagtga
     7801 gtttcctact agcattacag gagatttagt ttttccagcc aaaactccaa cagataatcc
     7861 gtctattaaa tcatcttgtt tattcattcc atttttagca acatataaat tgtctatctt
     7921 agaatccttg taaaattctt ttattacttt tgcattagtt tcatttctag tgctacctga
     7981 tattctctgt ggattttgaa gtttactttc tatattttta gaaactgtat attctccacc
     8041 gattacataa gatttatcaa tctttttgtt tttaaacaag ttatttattt cagttatatt
     8101 actattttca ttagtaagta ttataggcat atcattttga gctgatacag ctccaatgct
     8161 tactgcatcg gctaatcctt tttcgccatt aactactgaa atctttgata tattgctaat
     8221 attgttcaat tctttagcaa tgttcataga agtttgatat ctatcacttc ctgaaattct
     8281 agatacagag atattgtttg attttatagt atctaaagat ttttcattta tagaagcttc
     8341 tccaccaact acatatacat ttttaacttt taatctcttt aattcagcca aagttttttc
     8401 atttatttga gagcttccag tcaataatat aggagcgttt ttcttgtatg caaatggtgt
     8461 tgcagccaaa gcatctgcaa ttgctgaatc gtttattaaa actgcatttt cagcattttc
     8521 ccaacctgct tgacttatct taatagaagt ttcatatcta tcagttcctg taagtgcact
     8581 tgcatttact tcatcttgat atgtaacctc aaatctagca tttggacttc ctaagaaaac
     8641 aattacgcct ccttttggca atctaactct attgttcttt gtaactaaag aatagtttac
     8701 aggaacacct ttatcatcat aaacagcaaa agctgaattt tgaggaagat taacttctat
     8761 ttttttattt gcgatatcgt caccaatctt ataccatttt gcataaccat tggattctag
     8821 ttcacaagta aaagattttt ctgctggcaa attagttata gaatcttcac taacatacgt
     8881 tagtgttcca aaagataaat actctgtacc attttcttta tgaagtttaa tgtcggataa
     8941 atcacgacct attacaccag gtatttctat aaaagcattt gagttattct catccattat
     9001 tttagtgtta actatataac ctggagtttc atcagaaaga ctaaaacttg cttttacaga
     9061 gccaaacata tagctttgag aagtatattt ttcatccact agatagtaac ctttgccact
     9121 tctttttttc cacacttctt tgacactatt tgatatattg ttgtcatcta ctttttgagc
     9181 tacatagtat aaacttgctg tctgacctaa tccagggaca tcatcataag agctcatatt
     9241 taaatatgtg atattatttt tttcttttac aaattttaaa caactattac ctttttcaga
     9301 tacaaatcta tcttgaccta tgtatacgta tttatcttca ggtccatttt ctatataagg
     9361 agaagatact gttaaagtac cattatcatt aacatctact tttatcatat ttgaagaagc
     9421 ataaagacca ctattttctt ttaaagagct aggcatttta acttgttgtg gcttactaaa
     9481 tgttttatca ggttttattt ctttaatttt acctttttct tttaatgcag atagtaagat
     9541 ttcttgtcca attatttcat taagttgact acttccacca gaagaaagaa ctgcaactgc
     9601 catattttca tctggaagaa ctataagatt actgtggaat aataaagaat ctccaccttt
     9661 tgtaagagct tttaaattat actgattaaa tggataagtg ttgacacaat cccaccctaa
     9721 accatatcca agtatagagt cttctccttc aggccataga ccatttaaat attctttgtt
     9781 ttccatagct tttactgaag caggagaaag aataccattt gaatttttca taaatgtttg
     9841 tgcaaatgta catagatttt ctgcacttga atataaacca cctgcaccta tagcattaag
     9901 gttatcttgt ggaactgcat cttcccaata aggtacatat gcttttgcta gttttgaact
     9961 atcaaaacta ttttctggag tttttgtatt ttgtaagtta agtggattat ttatgtattt
    10021 atcaagaaaa ttagtaaatg acataccaga tactctttct actaaaattt cagctaaagt
    10081 aaatccatca ttacaataaa cagaaaaagc tcctggttta gcttttaatc tttgtttttg
    10141 taattctttt aagaaattat catgaccata agaatcattg tctgctaata aaatagtgtt
    10201 tttaaaacta cttcccatca accctgatga gtgatttaat aacattcttg gagtgatttc
    10261 cttgtatcta tcatcagcca ttttaaattc aggtatatac tttacaacag gagtatctaa
    10321 atttaatttt ccatcatcaa ccaacttcat aacagctgtt gtagtaaaca ttttactgat
    10381 agatgcgata ctatacatat tatccttatt taagtttttg ttatcctgtt tgctgtaaac
    10441 tccaccatta ccagaaatct caattttgcc attatcaatc aaagcatatt gagcacttac
    10501 agcaccatac tttgatagca aagtttggat tttctcttta gcaagagctt tagtttttgt
    10561 gtaagattcc gcgtttttac tataatcatg taattctata tcagaacttt gatatttttc
    10621 ggaattatct tttgtattat cagcaaaagt aatatttgga gcagcagtaa ataacatact
    10681 caatactaat gtactagata ataatttaga gagcctttgc ttaaacatat tacattacct
    10741 ctttcccttt ttaataattt ataattagca taacattctt aattatttta atcaacagat
    10801 tattatcaat aaaaaaagct tttataagta tagcttttta tataacagag aaaaatataa
    10861 aaataatatt tgttgttgta taaagaataa agggtatagg taatatataa ataaaatgga
    10921 ggaattttag acatatgtat aagaatataa ataagaagca acttaaagaa atgatgaaaa
    10981 atgaaaagga tgttttatta ttagatgtaa gaactaaaga tgaatttaag gaatataaaa
    11041 tagaaaatgc tataaatata tctttacaag agttaatcaa taatatagat gaaatttacg
    11101 attataaaga taagaaagta gtagtttatt gcagaagtgg tcatagaagt gttactgcat
    11161 gtaatttgtt agctgaagaa ggttttgagc atttatataa tttaaattca ggaataattg
    11221 attatatgag ttaaataatg taagttatac attaaatact atgtatagct ctgcttatta
    11281 agtaggaata tatctaaata tttataagat aaatttagga aagaacgaat tttttcgttt
    11341 ttttctatga cagtttttgt agtaaatatt agtttttaag ttggaaaaag gtagtagctt
    11401 tttagctact accttttaat atgaacttag aatattatta aaaaaatata tttaaagaca
    11461 gaattaattt tttaatgacc agttaaatta ctatcgccga atttatcatt aaatggtttt
    11521 ataactctat ttataggtcc ttttagaagt acatttaaac aaatagacag aatcataaat
    11581 agtaatagaa ctagtatatc tttagttaga tttggagcat atataccacc aactgcttcc
    11641 cttgtagcac ctattgcata ggtaaatggc attatagggt ttattctttg gaagaatgta
    11701 ggtgtaactt gtatagggaa tgtaccacca gaagaaccaa tctgaacgac taatagtact
    11761 attgcaattg cttttcctac atttccaaat acagaaacta aagaatacac tataaagtta
    11821 aataccatac tagtaaacat aagcagaact atcaataaaa ttggatgttt tgctgttact
    11881 cctaacaata atatatctcc agttcctatt ataaaacctt ggacaagagc tatacttaaa
    11941 aaagtaaggc ctcttccaaa gtaaatttca taaggtttat agtttccatg tacagatgta
    12001 gacaatagtg ctgaaataag taatatacca acccatgtag aaagaacact ataaaatggt
    12061 gtcattgcag aaccataatt ttcaattgga tataatttct ctgttttcac ctcaacaggt
    12121 tcttttaaga aattagactt tgtcaatata tcactttcaa gcaagctgac taattttttc
    12181 atatcttcac cattactaat tttgcttaaa gtatcaatca aatcatccaa cattcctttt
    12241 gctaaaggaa gtctttctct tatcaatgat atactttcct gtgcatttcc tgaaagtttt
    12301 agagaagtag taagtatttc ttcaaccttt ggaagttttg cttctgcctt atctaaaaca
    12361 gtaattatat catttgctac ttttatactg tttgcaaata tactatttat aggttttgat
    12421 atttttgagt caaaattatt taaaatattt aaattaattc ttccaatacc atttgataga
    12481 cttaaaacat tattcaaagc acttatagat ggttgttgtc cagatataac tttgttttta
    12541 atatcattta atgttgatat agatgaatct attttattgc tagagtcttc aagattatct
    12601 atgacatcat ccaatctatt atttgatgta agttggttta atttagttaa aaaatccacc
    12661 aaagtatcat ttaaagattg caaattagaa agtttttctg ataaattatc tatcaactta
    12721 ggtacatctt cactgccact atttactgca tcaattaaat ttaatgtaag agaagaagca
    12781 gaagatgaaa ggtcaaccat taaatttaag tcagacttaa taagaggaga aagttcgtct
    12841 aaattatcat ttgtatcctc taagaatttt tttaagtcac ttgataatag ttttgtatca
    12901 ttcagagtct ttttaattgt aggtaaatca gatttaatat ctttaactgt atcagataat
    12961 tttgaagtag catcagaagc taaatcaaca gtcttattta tatggtcaaa tctcttttga
    13021 aggtcaataa gggaattttc aacttttgtc aattttggaa gactgtgttc aattcctgca
    13081 ccaactccgt ttgatatacc aagaacgatt tcactaactg tttttactat agtctgatta
    13141 acctgtagtt gtattgtaga agcaccttta tctgtaatct ttggtgcaac tgcatttatt
    13201 ttttcattaa cagtatagat aatttcgcct tttttaacat catctgtaat taaagatgtc
    13261 aaatcttttg taaaattttt tggaatctta agtgatgcat aataagtacc ttttttaaca
    13321 ccttcaagag cagttttttc atctacaaac tgccaaccta aactcttgtt atctttgagt
    13381 tgttcaatta attggtctcc tacattaatc ttttgtcctg ctatttcatt tcctttatct
    13441 tcatttgtta ctgctacaag catattagca gtgcttccat aagggtccca agatgccttt
    13501 atattgaacc aagcatacag agatggtaaa aaagcaagac ctaaaactat tacaagtacg
    13561 gcataattgc cacgtatatc ttttaggtca cttttaaaaa tttctaatat attttttaaa
    13621 ccctttgaag gtcttaaatt cttgatatta ttccagttta aaatttcttt taaactatta
    13681 gtttttttca aatgtctcac ctcctaaaat attttgataa agaaaaaagt tagatttata
    13741 atcaatttta aattatatta ctttttacac aaatagtaaa gttaaaattt tgtcttaatt
    13801 ttaa
//
LOCUS       DAMJVG010000095        13775 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.098, whole genome shotgun sequence.
ACCESSION   DAMJVG010000095 DAMJVG010000000
VERSION     DAMJVG010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13775)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13775)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13775
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.098"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            159..299
                     /locus_tag="PC512_003174"
     CDS             159..299
                     /locus_tag="PC512_003174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442903.1"
                     /translation="MGIIESASKLAEMVHLLAVEKGITDIEAWDEAVKEYSKIYEERR
                     NE"
     gene            complement(474..794)
                     /locus_tag="PC512_003175"
     CDS             complement(474..794)
                     /locus_tag="PC512_003175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HDF2442904.1"
                     /translation="MKLKTISLPELNNLDPTLESTFIKMGEEQGELAECIGKFRNLSG
                     ENNDLDEVDIIKKTAKELMDVAQTCVTMMFKLEEQYGINLDEIRKEHIKKLEKRGYIK
                     NMDK"
     gene            complement(914..1651)
                     /locus_tag="PC512_003176"
     CDS             complement(914..1651)
                     /locus_tag="PC512_003176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HDF2442905.1"
                     /translation="MDANSLKDLIANHNNIVFFGGAGVSTESNIPDFRSSTGLFSQKL
                     NKQFTAEQLVSHTFFVRYPEEFFEFYKDKLIYPNAKPNNAHIALAKLEEMGKLKAVIT
                     QNIDGLHQMAGSKNVLELHGSVHRNYCTKCGKFFDLESMLNLGGNIPYCDNCGSIVKP
                     DVVLYEEALDSDVITKTISAISNADLLIIGGTSLAVYPAASFIDYYKGDYIALINKAN
                     TVYDKSASLVINKPIGEVLYEAVLRQI"
     gene            1866..3689
                     /gene="acd"
                     /locus_tag="PC512_003177"
     CDS             1866..3689
                     /gene="acd"
                     /locus_tag="PC512_003177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosaminidase"
                     /protein_id="HDF2442906.1"
                     /translation="MKKKAALATLAMLPLGVVNAHADGDIGIVTINYLNVRNEPTAES
                     SIAFVAKKDDKVLIKDSSNGWYKIKAESGQEGWASSKYIAKSNSDSLRTSTNKEKQVI
                     SNSLNMRNGAGTSYRVITVLKKGQKVEVISESNGWSKIKYDGRLGYVSSSYLGDVSNS
                     TNKSKTKQVNTTSLNVRSGPNTSYGLLGKLPKGSKVEVISESNGWSKIKYNGKDAYVS
                     SMYLSDVSQSNSDNSSQSNDKKNTDKVVNTASLNVRSGPGSTYSKLGKVYKGSKVTVL
                     SESSGWAKINFNNKEAFVVGNYLSTSADTSNNNSNSNSDNSSNSNGNNSSSSGQVNGM
                     SGISGAKIDYKSLSYTLESHISKQVEKAASGGNVIAPSNRKSTPSPEFSTFSAQRTSS
                     FVNASSSDIEYYLNPKNFTNTTKGMMQFLKINSYRDGISESSLNSYLNGLSSSVFKNQ
                     GAAFINAAKKYNIDVVYLVSHAMWETAYGKSTLAQGQTLTSYKGQPLSKPVKVYNFFG
                     IGAIDKSANVSGAEAAYSNGWTSVEATIDGSAKWISQNYVNSSKYNQNTIYKMKWNYD
                     YTWHQYATDVNWANGISGIMENLIGLYGGGSSLVFEVPQYK"
     gene            3904..8202
                     /locus_tag="PC512_003178"
     CDS             3904..8202
                     /locus_tag="PC512_003178"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HDF2442907.1"
                     /translation="MESIKEYLDKLEINNSGLGKQLKEVYINRVVYFKEDKIVYFYLT
                     SKDIVSHELLDKFKEELMYKLDYFKDMRMKIRFTGLERKSNKDVIKKYWNNILYILKY
                     LCPSIAGWYKQVEFLCLEEELKIKLPKGIFYERLMKKNVTYVLKTVLSEELGLDLNIT
                     IEKAVDEKVNKERLIRINDREMEEKIRALEIGKVNNCEENEEESYVIKSDVDENLIYG
                     DNANAMIENIVELNASSGTVAVVGDIFDVDTKELKNGKILMIASITDYTSSISCKLFL
                     TDTNKDGVLENVKKGAYLKIKGDIVYDTYQREISMMISGIRKETRIEREDKSEEKRVE
                     LHAHTQMSSMDAICSVKKLVERAAKWGHSAIAITDHGVVQGFPDAMNAGKSNNIKILY
                     GVEGYLVEDDSLIIEDANDKELSQTFVVFDIETTGFSNTNDKITEIGAVKIENFKIVD
                     RFSELINPEKDISYKIQELTGITNELIKDKPTIEEVLPKFMEFVGDSVLVAHNAEFDT
                     GFISQKCREQGLLYNNKKVDTLMLARVMLPNLKRHRLNVVAKELGIPLLNHHRAVDDA
                     EATALIFNKFLQMLTEKGAKTLSDVNNILGKIDYTKLSTNHITLIAKNSIGIKNLYKI
                     ISDAHVNHFFRAPRILRSVLNEYKEGLIIGSACEAGVVFQAVKKNVSDEEMKKIIDLY
                     DYIEVMPIDNNRFMIDKGEVKDEEELRELNRKLIDTAKKFDKIPVATGDVHFLDKHEA
                     VLRKVLKYSQGFKVDEEETYLHFRTTDEMLEEFSYLGEELAYEVVVENSNLIADMVED
                     IKPIPDDTYPPIIEGSDVELREMCYKKAKRIYGDPIPEIVQKRLDRELNSIISNGYAV
                     MYIIAQKLVAKSLSDGYLVGSRGSVGSSFAATMSDITEVNPLPAHYICENEDCKYSFF
                     YEIGEWGSGVDLPDKDCPKCGRKLAKNGHDIPFEVFLGFEGDKEPDIDLNFSGNYQPT
                     IHKYTEELFGEGYVYRAGTIGTVAEKTAFGYARKYVEENNISVPNAEVLRLSNGCTGV
                     KRTSGQHPGGVMVIPDYKDVYDFTPIQYPANDTSCGVITTHFDYHSISGRILKLDILG
                     HDGPTIIRMLEDMTGINITEIPLDDKETMSLFTSTEALGVTPEEINCPIGCLAVPEFG
                     TKFVRQMLLDTKPTTFAELVRISGLSHGTDVWVNNAQDLVREDIVGLKDVISTRDDIM
                     NYLIFKGLPPKMSFTIMESVRKGKGLKPEHIEEMKKNNVPEWYIGSCKKIKYMFPKAH
                     AVAYVMTSFRIAYCKVHYPEAFYATYFTTKVEDFDADLIVKGLDAIKSKINEIESLGN
                     DATTKEKGMLTVLEVALEMYARGIKLLPVDIYKSDATEFIVVGEKTLLPPMAAIQGLG
                     GNAAINIQNERKNGEFISKEDLRKRTKISKTVIETLTNHGSLENMSERNQLSLF"
     gene            8406..8867
                     /locus_tag="PC512_003179"
     CDS             8406..8867
                     /locus_tag="PC512_003179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HDF2442908.1"
                     /translation="MKKNLEATIEEIVTKITDEHGFEMVDVEYVKEAGEYYLRVYIDK
                     EEGISLNECELVSRELSPILDEKDPIKENYFLEVSSPGLDRALKKDRDFVRYQGRDVD
                     LKLYKPLNGCKQFEGELVGLTEDNNIKIIANGKEMEFNRKDVAIVRLAIKF"
     gene            8897..10051
                     /gene="nusA"
                     /locus_tag="PC512_003180"
     CDS             8897..10051
                     /gene="nusA"
                     /locus_tag="PC512_003180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HDF2442909.1"
                     /translation="MNHEFMEALDELVVDRGIDKEILIDTIEQALLTAYKKNFGSAQN
                     VRVEFDRDKGDIKVFSQRVVVDESDLYDTFLEIELADAREINPNYELGDIIEHEVTPK
                     NFGRIAAQTAKQVVVQRIREAEREIVYNEFIEKENEIVTGEVARANKNVVYVNLGRIE
                     GIMTQSEQIPFENYKAGQKIKFYILEVKKTNKGPQIVVSRSHPGLVKRLFEEEVPEIY
                     EGIVQIKSVAREAGSRTKMAVRSIDEKIDPIGACVGPKGLRVKNIVDELGDEKIDIIK
                     YSEDPAEFISAALSPSKVVRVDIDEDEKSALVIVPDYQLSLAIGKEGQNARLAAKLTN
                     WKIDIKSESQAEQEMLNLENSKEIEAEDVEAEFIDQEELDTSEDNFSEEE"
     gene            10058..10339
                     /locus_tag="PC512_003181"
     CDS             10058..10339
                     /locus_tag="PC512_003181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HDF2442910.1"
                     /translation="MILKKVKKVPQRKCIACQDRDSKKELIRIVKNKEGKIFLDPTGR
                     ANGRGAYVCKSSECLKKAIKSKALNKAFKIDVPDEVYDNLLMELEEYEK"
     gene            10329..10640
                     /locus_tag="PC512_003182"
     CDS             10329..10640
                     /locus_tag="PC512_003182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal L7Ae/L30e/S12e/Gadd45 family protein"
                     /protein_id="HDF2442911.1"
                     /translation="MKNNKEKVLSFLGLATRAGKIVSGDDSTLLDLKKGKVNLILIAE
                     DASNNTKKLFKDKSTFRNIPYLFFSTKEEIGFAIGKSPRAVVGIKDENFSKKIIELIE
                     I"
     gene            10662..12602
                     /gene="infB"
                     /locus_tag="PC512_003183"
     CDS             10662..12602
                     /gene="infB"
                     /locus_tag="PC512_003183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HDF2442912.1"
                     /translation="MSKTRVYQIAEELNISNEELINKLAELDINVTDKDSVLEGEELE
                     LALEMLGEDLSQENGNVIEIDGKLTVQVLATKLDKSPSEIIMKLMKMGTMATINQEIS
                     FEIAALAAKDYGFELTVAESDDTEALEIEALMEIEEDKEEDLKPRPPVVTVMGHVDHG
                     KTSLLDAIRKTDVISGEAGGITQHIGASEVKINGHKIVFLDTPGHEAFTSMRARGAQV
                     TDIAILVVAADDGIMPQTVEAINHAKAAGVPLIVAINKIDKPGANPDKVKQELADQGL
                     LVEDWGGEVIAVPVSAKKKEGIDTLLEMVLLVAEMEELRANPNKRAVGTVIEAELDKG
                     RGPVATVLVQGGTLTVGDPIVAGVACGKVRAMINAKGKRVKTAGPSTAVEILGLSEVP
                     QGGDQFVEVPTDKIARSVAARRQQIVRDEMLKSTQRLSLDALFSQMSEGSIKDLNIVI
                     KADVQGSVQAVKQSLEKLSNEEVQVKVIHGGVGAVTESDILLAAASNAIIIGFNVRPV
                     PGAESLGEKENVDIRTYTIIYKAIEDIQAAMTGMLDPEYVDEETGKAEIREIYKISGV
                     GTVAGCYVTNGKIFRNCKVRLVRDSIIIHEGELAALKRFKDDVKEVNSGYECGMSFVN
                     YNDIKEGDIVEAYITKEVERKL"
     gene            12645..13025
                     /gene="rbfA"
                     /locus_tag="PC512_003184"
     CDS             12645..13025
                     /gene="rbfA"
                     /locus_tag="PC512_003184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HDF2442913.1"
                     /translation="MASYNRTRRIAEEIRKVVSTMLINGVKDPRITSMVSVTDVEVTN
                     DLRYAYVYVSILGGDEESTLTGLKSAGGYIRREVGKNIKLRYIPEIVFKLDDSIEKGM
                     YMDSLIKRVNEKNAQQNEDENYDE"
     gene            13006..13683
                     /locus_tag="PC512_003185"
                     /pseudo
     CDS             13006..13683
                     /locus_tag="PC512_003185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438308.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
BASE COUNT         5498 a         1566 c         2587 g         4124 t
ORIGIN      
        1 ttaataggta aaatatccta ttgttttgta gatatatcct aattatgtca aaaaataaaa
       61 aaatttttat ttattagagt ttttggaaat aataataaca gatattataa ttaattaaca
      121 gtttttgtaa gtatttgaca atagagaggg tgtaacaaat gggaataata gagtcagcat
      181 caaaattggc tgagatggtt catttattgg ctgttgaaaa ggggataact gatatagaag
      241 catgggatga agctgtgaaa gaatacagca aaatttatga agaaagaaga aatgaataga
      301 atgataaaaa atgaaaactt gatgataaaa aataacttta tttaaagaaa ttcaattttt
      361 atagaagtat taaaaataat ataaataaaa agatggtatt tcaaatgtaa gtaaaaaatc
      421 attttgggat accatcctta ttatttattt taataatata taagtaataa atcttactta
      481 tccatatttt ttatgtaacc tcttttttct aactttttta tatgctcctt acgtatttca
      541 tcaagattaa taccatattg ttcttctagc ttaaacatca tagtaacaca tgtctgcgct
      601 acatccatta gttccttagc agttttcttt ataatatcaa cttcatctaa atcattattt
      661 tctccactta gatttctgaa tttacctata cattcagcta attcaccttg ttcttcaccc
      721 attttgataa atgtagattc tagtgttggg tctaaattat taagctctgg taaagatata
      781 gtttttagtt tcataaaagc tcctttcaag ttattcgtat ttatactaaa acatcataac
      841 aaaaataata ctaaaaaaaa actttaaatt caacataaaa acttacatat ataataaaaa
      901 tcatgaaata aatctatatt tgtcttaata cagcctcata taaaacttct ccaataggtt
      961 tatttattac aagagaagct gacttatcat agactgtatt tgctttatta ataagagcaa
     1021 tataatcacc tttgtaataa tctataaaac ttgctgctgg gtacacagct aatgatgtac
     1081 ctcctataat caataaatca gcattactta tagcagaaat tgttttagta atgacatcac
     1141 tgtcaagagc ttcctcataa agtactacat ctggttttac tatagaacca cagttgtcac
     1201 agtaaggaat attacctccc agatttaaca tagattctaa gtcaaaaaac ttaccacatt
     1261 tagtacaata atttctatgt acagaaccat gaagttctag cacattttta cttccagcca
     1321 tttgatgaag tccatcaata ttttgagtta tgacagcttt aagcttaccc atttcttcga
     1381 gttttgctaa agctatatga gcattattgg gttttgcatt aggatatatt aatttatcct
     1441 tataaaattc aaaaaattct tctggatatc taacaaaaaa agtatgtgaa actaattgtt
     1501 cagcagtaaa ttgtttattg agtttttggc taaataatcc agtagaactt ctaaagtctg
     1561 gaatattaga ttcagttgaa acacctgctc caccaaaaaa tacaatatta ttgtgattag
     1621 ctattaagtc ttttaagcta tttgcatcca tagttacacc tccaaattat tatatataaa
     1681 ttgtactaca tattaggtcg tttatgtttt attaatttaa ataaatatat agtttaataa
     1741 gttaaataaa gggaatataa ataaaatgta tacagagtat aaatagacaa tatttactaa
     1801 aataacaagt tgtcgtataa ttatattaaa attgttttag tgtataagaa gggcggggga
     1861 agtacgtgaa gaaaaaagca gctttagcaa cattggctat gttaccctta ggtgtggtaa
     1921 atgcacatgc tgatggagat ataggtatag tgactataaa ttatttaaat gtaagaaatg
     1981 aaccaactgc cgaaagtagc atagcctttg ttgctaaaaa agatgataaa gttttgatta
     2041 aagactcttc taatggatgg tataaaataa aagctgaatc tggacaagaa ggttgggctt
     2101 catcaaaata tatagcaaaa tcaaatagtg actctttaag aacgtctaca aataaagaaa
     2161 aacaagttat ttcaaatagt ttaaatatga gaaatggagc aggtacaagt tacagagtaa
     2221 taactgtact aaaaaaaggt caaaaagtag aagtaatatc agagagtaat ggatggtcta
     2281 aaatcaaata tgatggaaga ctaggatatg tatctagctc ttatttagga gacgtttcaa
     2341 actcaactaa taaatcaaaa actaaacaag tgaatacaac ttcactaaat gtaaggagtg
     2401 gaccaaatac aagttatggt ttgttaggca agttgccaaa aggaagtaaa gtagaagtaa
     2461 tatcagaaag taatggatgg tccaaaataa agtataatgg aaaagatgcc tatgtatcta
     2521 gtatgtactt atcggatgta agtcaaagta attcagacaa ttctagtcaa agcaatgata
     2581 aaaagaatac tgataaggtt gtaaatacag cttctttaaa tgtaagaagt ggaccaggtt
     2641 ctacatatag taagttggga aaagtttata aaggaagtaa agtaactgta ctatcagaaa
     2701 gtagtggatg ggctaagatt aattttaaca ataaagaagc atttgtagta ggcaattatt
     2761 tatctacctc agcagatact tcaaataata actcaaatag taactctgat aacagttcta
     2821 atagtaatgg taataattct tcatcatcag gccaagtaaa tggtatgtca ggtataagtg
     2881 gggctaaaat tgattataaa tctttgagtt atactttaga atctcatata agtaaacaag
     2941 ttgagaaagc agcatcagga ggaaatgtga tagctccaag taataggaaa agtactccaa
     3001 gtcctgagtt tagtactttt tcagctcaaa gaacaagctc atttgtaaat gcaagttcaa
     3061 gtgatataga atattattta aatcctaaga attttacaaa tactactaaa ggtatgatgc
     3121 agtttttaaa gattaacagt tatagagatg gtatttcaga atcaagtctt aactcgtatc
     3181 ttaatggttt atcttctagt gtatttaaaa accagggagc agcctttata aatgctgcca
     3241 agaagtataa tatagatgtt gtatatctag tatctcatgc tatgtgggaa actgcttatg
     3301 gtaagtctac acttgcccaa ggtcaaacat taacatctta taagggacaa cctcttagta
     3361 agccagttaa agtatacaat ttttttggta taggagcaat agataaaagt gctaatgttt
     3421 caggtgcaga agcagcgtat tccaatggct ggactagtgt agaagctaca atagatggct
     3481 ctgcaaagtg gatatcacaa aattacgtaa atagttctaa gtacaatcag aatactatct
     3541 acaagatgaa gtggaattat gattatacat ggcatcagta tgcaactgat gtaaactggg
     3601 ctaatggaat ttctggaatt atggaaaatt taattggtct ttatggagga ggaagtagtt
     3661 tggtttttga agttcctcaa tataagtaat acataaataa aaaatataga ctatgggtag
     3721 ttttcatttt atttaaatta tctatagtct ttttgtatat aatttataat ctgtaaattt
     3781 aatgttaaca aaacttttat gttataatat taattctaag taaatataag tgagtaatag
     3841 gtagaaatag ataaaaagtg gtaataatat atataaagat aattttgaga aaggaggata
     3901 tatatggaaa gtattaagga atatttggat aagttagaaa ttaataatag tggtcttgga
     3961 aagcaactta aagaagttta tataaataga gtagtttatt ttaaggaaga taagatagtt
     4021 tatttttatc taacttctaa agatattgtt tctcatgaac ttttagataa atttaaagaa
     4081 gaattgatgt ataaactcga ttattttaaa gatatgagga tgaagataag atttactggt
     4141 cttgaaagaa aatccaataa agatgttata aaaaaatatt ggaataatat attgtatata
     4201 ttaaagtatc tttgtccatc tattgcaggg tggtataaac aagtagaatt tctttgttta
     4261 gaagaagaat taaaaataaa acttccaaaa ggtatatttt atgagcgatt aatgaaaaaa
     4321 aatgtaactt atgtacttaa aaccgtgctt agcgaagagt tgggattaga tttaaatata
     4381 acaatagaaa aagctgttga tgaaaaggta aataaagaaa gactcataag aatcaatgat
     4441 agagaaatgg aagaaaaaat tagggcttta gaaattggaa aagttaataa ctgtgaagaa
     4501 aatgaagagg aaagctatgt cattaagtct gatgtagatg aaaatttaat ctatggagat
     4561 aatgcaaatg ctatgattga aaatatagtt gaattaaatg catcttctgg aacagttgca
     4621 gttgttggag atatatttga tgttgacact aaagaactta aaaacggaaa aatacttatg
     4681 atagcttcaa ttacagatta tactagctca ataagctgta aacttttttt aacagataca
     4741 aataaggatg gagtacttga aaatgttaaa aaaggagcat acttaaaaat caagggtgac
     4801 atagtttatg atacatatca aagagaaatt agtatgatga ttagtgggat aagaaaagaa
     4861 actagaatag agagagaaga taaatcagag gaaaaaagag tagaactcca tgcacataca
     4921 caaatgtctt ctatggatgc tatttgttct gttaaaaagc ttgtagagcg tgcagccaaa
     4981 tggggtcatt ctgctattgc tataacagac catggtgttg tacaaggatt tccagatgct
     5041 atgaatgcag gtaagtcaaa taatataaaa atactttatg gagtagaagg gtacctggtt
     5101 gaagatgatt ctctcattat agaggatgca aatgataaag aactttcgca gacatttgtt
     5161 gtatttgaca tagagacaac tggcttttct aatacaaatg ataaaataac tgagattggt
     5221 gctgtaaaaa tagaaaactt taagattgta gatagattta gtgagttaat aaatcctgaa
     5281 aaagatattt cttataagat acaggaattg acaggaataa ctaatgaatt aattaaagac
     5341 aagccaacca ttgaagaagt tcttcctaag tttatggaat ttgttggaga tagtgtatta
     5401 gtagcacata atgcagagtt tgatactgga tttatatcgc aaaaatgtag ggaacaaggc
     5461 ttgttatata ataacaaaaa agtagataca cttatgttag caagagtaat gttgccaaac
     5521 ttaaaaagac atagattaaa tgtcgttgca aaagaacttg gtattcctct tttaaatcac
     5581 catagagcag tggatgatgc tgaagctaca gcacttatat ttaataagtt tttgcagatg
     5641 cttacagaaa aaggtgcaaa aactctaagt gatgtaaaca atatacttgg aaagattgat
     5701 tacacaaagc ttagcacaaa tcatataacc ttgatagcaa aaaattctat aggtataaaa
     5761 aatttatata aaataatttc agatgcacat gtaaatcatt tttttagagc accaagaatc
     5821 cttagaagtg tattaaatga atataaagaa ggattaataa ttggttcggc ttgtgaagct
     5881 ggggtggttt ttcaagctgt aaagaaaaac gtgtctgatg aggaaatgaa aaaaataata
     5941 gatttatacg attatattga agtaatgcct atagataata atagatttat gattgataaa
     6001 ggagaagtaa aggacgaaga agagttaagg gagttgaata ggaaactaat tgatacagcc
     6061 aaaaaatttg acaaaattcc agtagctact ggggatgttc attttttaga caaacatgaa
     6121 gctgtcttaa gaaaagttct taaatattct caaggtttta aagtagatga agaagaaact
     6181 tatttacatt ttagaacaac agatgaaatg ttggaagagt ttagttatct tggagaagaa
     6241 ttggcatatg aagttgtagt tgaaaatagt aatctgattg ccgatatggt tgaagatata
     6301 aaacctatac cagatgatac ttatcctcca attatagagg gctcagatgt ggagttaaga
     6361 gaaatgtgtt acaaaaaagc caaacgaatc tatggagacc caataccaga aatagttcaa
     6421 aaaagactgg atagagaatt aaattcaata ataagcaatg ggtatgcagt tatgtatatt
     6481 atagctcaaa aactggttgc aaaatctctt tcagatggat atttagttgg ttcaagaggc
     6541 tcagttggct catcttttgc agctactatg agtgatataa cagaagttaa tcctcttcca
     6601 gcacattata tttgtgaaaa cgaagactgt aaatattcat tcttttatga aataggtgaa
     6661 tggggctcag gtgttgattt accagacaag gattgtccaa agtgtggaag aaaacttgct
     6721 aaaaacggtc atgatattcc atttgaggtt ttcttaggtt ttgaaggtga taaggaacca
     6781 gatatagact taaatttctc aggaaattat cagccaacaa ttcataaata cacagaagaa
     6841 ctatttggag aggggtatgt atatagggct gggactatag gtactgtagc agaaaaaaca
     6901 gcttttggat acgcaagaaa atatgtggaa gaaaataata taagtgtacc aaatgcagaa
     6961 gtacttaggc tttcaaatgg atgtactgga gtaaaaagaa cctcaggaca acatcctggt
     7021 ggagttatgg ttataccaga ctataaagat gtatacgatt ttacacctat acagtatcca
     7081 gcaaatgata cttcttgtgg tgttataact actcactttg attatcattc aataagtggt
     7141 agaatactta aacttgatat acttggacac gacggtccta ccattataag gatgcttgaa
     7201 gatatgactg gaataaatat aacagaaatt cctttagatg ataaagagac tatgtctcta
     7261 tttacatcta cagaagcatt aggtgttaca ccagaagaaa taaactgtcc tataggttgc
     7321 cttgctgtac cagagtttgg aactaagttt gtacgacaaa tgttacttga cacaaaacct
     7381 actacatttg cagaacttgt acgtatatct ggtctctctc atgggacaga tgtttgggta
     7441 aataatgcac aagacttagt tagagaagat atagttggat taaaagatgt tatatctaca
     7501 cgagatgaca taatgaacta tttaatattt aaaggattac ctcccaaaat gagctttaca
     7561 ataatggaga gtgtaagaaa aggtaaaggt ttaaaaccag aacacattga agaaatgaaa
     7621 aaaaataatg ttccagaatg gtatataggc tcatgtaaaa agattaagta catgttccca
     7681 aaagcacatg ctgttgctta tgtaatgaca tcatttagaa ttgcatattg taaagttcac
     7741 tatccagaag cattttatgc gacttatttt acgacaaaag ttgaggattt tgatgcagat
     7801 ttaattgtta aaggattaga tgctataaaa tcaaaaataa atgaaattga gtcactggga
     7861 aatgatgcaa ccacaaaaga aaaaggtatg ttgaccgttt tagaagttgc tcttgaaatg
     7921 tatgctagag gaataaaatt attaccagtt gatatatata aatcagatgc aactgagttt
     7981 atagttgtag gagaaaaaac attacttcca ccaatggcag caatacaagg tcttggagga
     8041 aatgcggcta taaacatcca aaatgaaaga aaaaatggtg aatttatatc aaaagaagat
     8101 ttgagaaaga gaacaaaaat atcaaaaacg gtaatagaaa ctcttactaa tcatggttca
     8161 cttgagaata tgagtgagag aaatcaattg tcattgtttt aagttagccc aaaaagttgc
     8221 aaataaaaga attttatgat atcatagtat agaaaatagt atactttgca gaaactaaga
     8281 gtgagacagc tgttctcact cttttatttt aaatatatta ttaaaaagct ggtttatttt
     8341 tattaaatat attttattta agattatata aactggtcat ttacaattga ataggaggaa
     8401 ctttaatgaa aaaaaattta gaagctacaa ttgaggagat tgtaactaaa ataacggatg
     8461 aacatggatt tgaaatggtt gatgttgaat atgtaaaaga agcaggagaa tactacttaa
     8521 gagtatacat agataaagaa gaaggaatat ctttaaatga atgtgaatta gttagtagag
     8581 aattaagtcc aatactagat gaaaaagacc ctataaaaga aaattacttt ttagaggtat
     8641 cttctccagg gcttgataga gcattaaaaa aagacagaga ttttgttaga tatcaaggta
     8701 gagatgtaga tttaaaatta tataaaccat taaatggatg taagcaattt gaaggtgaac
     8761 ttgtaggatt aacagaagat aataatataa aaatcattgc aaatggtaag gaaatggaat
     8821 ttaatagaaa agatgttgct attgtcagat tagcaataaa gttttagtgg tatattaaat
     8881 agggaggata taaaaaatga atcatgaatt tatggaagca ttagatgaat tagtagttga
     8941 cagaggtata gataaagaaa tacttataga tactatagaa caagctcttt taactgcata
     9001 caagaaaaac tttggttcag cacaaaatgt tagagttgaa tttgatagag acaagggaga
     9061 tataaaagta ttttctcaaa gagttgttgt tgatgaatca gatttatatg atactttctt
     9121 agaaatagag ttagcagatg ctagagagat aaatcctaat tatgaattag gtgatattat
     9181 agaacatgaa gttacaccta aaaactttgg aagaattgca gctcaaacag caaagcaagt
     9241 agttgttcaa agaataaggg aagctgagag agaaatagtg tataatgaat ttatagaaaa
     9301 agaaaatgaa atagttacag gagaggttgc tagagcaaat aaaaatgttg tttatgtaaa
     9361 tcttggaaga atagaaggta taatgactca aagtgaacaa ataccatttg agaattataa
     9421 agcaggtcaa aaaataaaat tctatatact tgaagttaaa aagactaaca aaggacctca
     9481 aatagttgta tcaagaagtc atccgggtct agtaaagaga ttgtttgaag aagaagttcc
     9541 tgaaatatat gaaggaatag ttcaaataaa atctgtagca agagaagcag ggtcaagaac
     9601 taaaatggca gtaagatcta tagatgaaaa aatagaccca attggagctt gtgttggacc
     9661 aaaaggactt agagtaaaaa atatagtgga tgaacttggc gatgagaaaa tagatataat
     9721 aaaatatagt gaagacccag cagagtttat atcagcagca cttagcccat caaaggttgt
     9781 tagagtagat atagatgaag atgaaaagtc tgccttagta atcgttccag attatcagtt
     9841 atcgcttgct ataggtaaag aaggtcaaaa tgcaagacta gcagcaaaat tgactaactg
     9901 gaaaatagat attaagagcg aatctcaagc agaacaagaa atgttaaatc ttgaaaattc
     9961 caaagaaata gaagctgagg atgttgaagc tgaatttatc gaccaagaag agttagatac
    10021 ttcagaggat aattttagtg aagaagagta aggagggatg attttgaaaa aagtaaaaaa
    10081 agtgcctcaa agaaaatgca tagcatgtca agatagagac tctaaaaaag agcttataag
    10141 aatagttaaa aataaagaag gaaaaatatt tttagaccca acaggaagag ccaatggaag
    10201 aggagcatat gtatgtaaaa gctctgaatg tctaaaaaaa gctataaaga gtaaagcatt
    10261 aaataaagct tttaaaatag atgttcctga tgaagtctat gataatctac ttatggagtt
    10321 agaagaatat gaaaaataat aaagaaaaag tactttcgtt cttagggctc gcaactcgtg
    10381 cagggaaaat agtgtctggt gatgattcaa ctttgcttga ccttaaaaaa ggaaaagtaa
    10441 atttgatttt aatcgcagaa gatgcatcaa ataatactaa aaaacttttt aaagataaat
    10501 caacttttag aaatattcca tatctatttt tttcaacaaa agaggaaata ggatttgcaa
    10561 taggaaaatc tccaagagca gttgtaggaa taaaagatga aaatttttct aaaaagataa
    10621 ttgaactaat agaaatttaa aataaaatag ggggtgatct tgtgtcaaaa acaagagtat
    10681 accaaatagc agaagaatta aatatatcaa atgaagagct tataaataag ttagctgaat
    10741 tagatataaa tgtaactgac aaagattcag tattagaagg tgaagagtta gaattagcac
    10801 ttgaaatgtt aggtgaagat ttatctcaag aaaatggaaa tgttatagaa atagatggaa
    10861 agttgacagt acaagtatta gcaacgaaat tagataaatc tccatcagaa ataattatga
    10921 agcttatgaa aatgggaact atggcaacaa taaatcaaga gataagtttt gagattgctg
    10981 ctttggctgc caaagactat ggatttgaat taacagtagc tgaaagtgat gatacagaag
    11041 ctttagaaat agaagcttta atggaaattg aagaagacaa agaagaggat ttaaaaccta
    11101 gaccaccagt tgttacagtt atgggacatg ttgaccatgg taagacatct ttactagatg
    11161 caataagaaa aactgatgtg atctcaggtg aagctggagg aataactcag catataggtg
    11221 cttcagaagt taaaatcaat ggacacaaaa tagtattttt agatactcca ggacatgagg
    11281 ctttcacatc aatgagagca agaggagcac aagttacaga tatagcaata ttagtagttg
    11341 cagcagatga tggtataatg cctcaaacag ttgaagctat aaaccatgct aaagcagcag
    11401 gtgtaccttt aatagttgct attaataaaa tagataaacc aggtgcaaac ccagataagg
    11461 ttaaacagga attagcagac caaggattat tagttgaaga ctggggtgga gaagtaatag
    11521 cagttccagt atcagctaag aaaaaagaag gaatagatac acttttagaa atggtattat
    11581 tggttgctga aatggaagag ttaagagcta atccaaataa aagagcagta ggaactgtta
    11641 tagaagctga gcttgataaa ggaagagggc cagttgcaac agtacttgtt caaggtggta
    11701 ctttaacagt aggtgaccca atcgttgcag gtgttgcatg tggtaaagtt agagcaatga
    11761 taaatgcaaa aggtaagaga gtaaaaacag caggaccatc tacagcagtc gagatattag
    11821 gtctatcaga agttccacaa ggaggagacc aatttgtcga agttccaact gataagattg
    11881 ctagaagtgt agcagcaaga agacaacaaa tagttagaga tgaaatgtta aaatcaactc
    11941 aaagattatc actagatgct ctatttagtc aaatgagtga aggttctata aaagacctta
    12001 atatagttat aaaagcagat gtacaaggtt cagtacaggc agttaaacaa tctttagaaa
    12061 aattatcaaa tgaagaagtt caagttaaag taatacatgg tggtgttgga gctgtaacag
    12121 aatcagacat attacttgca gcagcttcta acgcaataat aataggattc aatgtaagac
    12181 cagttccagg tgcagaatct ctaggagaaa aagaaaatgt tgatataaga acatatacta
    12241 taatatacaa ggcaatagaa gatatacaag cggctatgac tggtatgtta gaccctgaat
    12301 atgttgatga agaaacagga aaagctgaaa taagagaaat atataaaata tctggtgttg
    12361 gaacagtagc tggatgttat gtgactaatg gtaagatatt tagaaattgt aaagtaagat
    12421 tagttagaga tagcataata atacatgaag gtgagcttgc agcacttaag agatttaaag
    12481 atgatgtaaa agaagttaat tctggatacg aatgtggtat gagttttgta aattataacg
    12541 acataaaaga aggcgatata gtagaagctt atataactaa agaagtagaa agaaaattat
    12601 aaattcgtat caaagaaaat cagttagtaa agaaggtcga tggtatggca tcatataata
    12661 gaacaagaag gatagcagaa gaaataagaa aagtcgtaag tactatgctt ataaatggag
    12721 taaaagaccc tagaataaca tctatggtga gtgtaactga tgtagaagtt acaaatgacc
    12781 taagatatgc ttatgtatat gtaagtattc taggcggaga tgaagaatcc acactaacag
    12841 gtcttaaaag tgctggagga tatataagaa gagaagtagg aaaaaatata aaacttagat
    12901 atattcctga gatagtattt aaacttgatg attcaataga aaaaggaatg tatatggata
    12961 gccttataaa aagagttaat gaaaaaaatg ctcaacaaaa tgaggatgaa aattatgatg
    13021 aataatatgg atagtattat aaactatatt tatgagggtg actattttat agttacctct
    13081 catatcagtc cagatggaga caatattggt tctacacttt caatgtatta tacattgaag
    13141 aatttaggaa aaaatgtata ttatgtactt gatgatgaag ctccattaaa tttaaggttt
    13201 ttggttgaag gtgtaaaaat ctataagtct aatgaattta atatgaagaa ctattctcta
    13261 attgcacttg attgtgggga taagatgaga atatgtgtga gtgatgaaat caaaaataat
    13321 gcatcaaaat taatctgtat tgaccatcat gctagtaatg attcatatgg agatttaaat
    13381 tatgtagata ttgatgcatc ttctacatgt gaattagttt ataatttatt agttagattt
    13441 cagcaaataa aagatattaa tattataaat gaagatatag caacatgttt atatacaggt
    13501 cttgtaactg atactggaaa cttttcgtat tcaaatgtac atgcaagtag ctttgaaatg
    13561 gcaaaaaatt tacttgtttt aggtgcacaa aaaaatacta taatacaaaa tatatatcaa
    13621 agcaattctt ctggttatta caaattatta ggagaagctc taaagggttt ggagatattt
    13681 gattaaaaaa tagttacgca cactcgtgac tttagtcatg agttagtagc taaaatagtc
    13741 agcatatagg gaaacttata tgtagagata ggata
//
LOCUS       DAMJVG010000096        13685 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.099, whole genome shotgun sequence.
ACCESSION   DAMJVG010000096 DAMJVG010000000
VERSION     DAMJVG010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13685)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13685)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13685
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.099"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            51..1844
                     /locus_tag="PC512_003186"
     CDS             51..1844
                     /locus_tag="PC512_003186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDF2442914.1"
                     /translation="MNIKDRLSGLRKFMEEKNIDAYMIPSSDNHQSEYVGDYFKSREF
                     ISGFNGSAGTVIVTKDEAGLWTDGRYFIQAESQLEGSTIKLFKMGQEGCPTTDEYLYK
                     NIPEGGTLGFDGRVISAREGATLAEKLSKKGIKIEYQYDLIDSIWPDRPALSDSKAFL
                     LDVKYCGESFSSKLARLREKMSEKGTSTHVITTLDDIAWLFNIRGGDVKYNPVVLSYA
                     VITLKEVYLFVDESKLNEEILNELAKENVQIKPYNDVYEFVKNIDKTEKVLLDGTKLS
                     YTIYNNIPCEVEKVDEFNPVMFFKAQKNEVELENIRNSHVKDGVAFTKFMYWLKKNVG
                     KMEITEISATQKLEDLRREQEGFFEPSFNTIAAYKEHAAMMHYSATPESNYKLEAEGL
                     FLVDSGGQYYDGTTDITRTTVLGPISDELKLHFTSVARGMINLSKAKFLHGCRGYNLD
                     ILSRSCMWNMGIDYQCGTGHGIGFVLNVHEAPNGFRWRVVPERFDSAVLEEGMVTTNE
                     PGIYIEGSHGIRTENEIVVRKAEKNFYGQFMEFEVVTLAPIDLDGIVPELMNKDEKDY
                     LNWYHKLVYDKISPFLTDEEREWLKVYTRAI"
     gene            complement(1925..3307)
                     /locus_tag="PC512_003187"
     CDS             complement(1925..3307)
                     /locus_tag="PC512_003187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HDF2442915.1"
                     /translation="MSVLKTQEKLKQPRDLYFCCSIFTFVGLAYYGMKLVLLLFLAEQ
                     VSKGGLGLTPAESASMLASFLAWTYFSPVIGGWVSDRFLGPKNCIILGMLMVSIGYFL
                     GYIANSKMDINIMIFLSGLGIGFYKGNLHTMVGNLYTNDDPRKDGAFSITYMATNLGT
                     LFGPLICGLVANEWFAMKSGLSISMYGYRYVFLFSSITVLIGLFFFIFGNRKFYKPLN
                     NDPSNGRESIRKSLEYKKMLASRPLTLIEKKRIIVILVLAFFTVFFWIAYNQASMSIA
                     LYTKEHINLTVGNFQIPTSWIDSYNGLLCVILGPISALVWVKLSQTKKGDLSVPKKMS
                     LGFILLAIAFLFMIVAVIQTGTDPNSIHKASVFWVVGFLTFQSIGEICFSPVGYGMVN
                     KLSPEKYISFLMGVWFLGKFAANKLSGYTQAIIDQLGMLQVFIVIPSFLLIFGIILLI
                     MNKKLVELSN"
     gene            3565..3912
                     /locus_tag="PC512_003188"
     CDS             3565..3912
                     /locus_tag="PC512_003188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HDF2442916.1"
                     /translation="MIRKKSELQVEVKENLNGGIGKVKLENIIQNEELKGKGRLFKRV
                     ALPVGSSIGVHDHTTDFEVYYILKGKGKVFDNGEFVEVNEGDVVYTADGEKHSIENIG
                     EEDLEFVALVLYM"
     gene            3930..4964
                     /locus_tag="PC512_003189"
     CDS             3930..4964
                     /locus_tag="PC512_003189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442917.1"
                     /translation="MTGKIEEIKDKINRFCNSNLNQEYKDISFKILQNLLDNNKEIIH
                     SSRADIWSSAILNIVLEQNLLYNKKHPLHITKKEFSKQIGVSLNTINNKSSLIKDVCS
                     IDFLNQDTIAISNVEFWVKETNSKSKSVDLDLEKKKILYKRYIKLSQDANSDIESIRY
                     MEEAVNIGKSMITKEDKELGFWKGLSTRAYMIALESLARKLESINNLKESKKVLEYLI
                     EINPSDEQGIRYKLLNVLIRLNDRTSINKLFELYKEEKSATWMYSKALYYFKNKSMFL
                     ANDSIKVARSKNKYVGLYLLDWRNAFGREFVTEEEKAEAVYYYDENIVIWNEVKGSMD
                     WLLKKMLEFS"
     gene            complement(5013..6062)
                     /locus_tag="PC512_003190"
     CDS             complement(5013..6062)
                     /locus_tag="PC512_003190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2442918.1"
                     /translation="MEINYKKRNFKSFAKRKNIEISVQRYLIDALSYMALGLFSSLLI
                     GTIFNTLGDNFNISLFTEVISPLAKQVTGPAIAVAIAYGLQAPPLVLFSCALVGACGN
                     ELGGPVGAFVATLFAVEVGKLVSKETKIDILVTPAVTILIGVLVAELIGPAVSAFMTS
                     FGNIIMQATTMQPIIMGALVSALVGIALTLPISSAAICMMLSLGGLAGGAATVGCCCQ
                     MVGFAVMSFRENGVGGLVAQGLGTSMLQVPNIIKNWKIWIPPTVASILLGPLSTTIFK
                     MENIPIGSGMGTCGLVGQFGTVTAMQSAGKGGISMWVGILLLNFILPAIVTLLISEFM
                     RKKGLIKPEDLKLDV"
     gene            6337..7872
                     /locus_tag="PC512_003191"
     CDS             6337..7872
                     /locus_tag="PC512_003191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442919.1"
                     /translation="MIFVKNKKYRKIAIIISIPILLVAQYYLFKFGILRPMVKGVEIE
                     IVDGEYVKDIDKYVVKLNETVTLSTGEYIKVPSYAKNPNIWFNVLDNSGTLKIDGNKM
                     TALKVGYSSVGIMKNSRVLKKATIKVVDPEVESLDMEINGDLKHVGDSATIESTIEVD
                     YDKFKKSYKPVYKSSNENILKIKGNKVSAVGVGKATIYAKCGNKEIERTFRIQARVAE
                     INMDDIKIEVDQNEKLKPDIITSPPGLEPPKIYYELVDSKLPVERAISLSSNGNVVGL
                     REGKDRVRITCGDKSKVITVTVVKETITNDYIQNLVGSHKIVNNKVIIKLEWDYMKDV
                     FDYDIYLKDKLSGESFKKIKSITINESDLGKSNKVYATIEVDMKGNQNIDFDIYVIGK
                     KDSDTTKPSNVINITNGNGNSNNDNNIKDMRVENISANVDRDNNVIRVNWSSISHKDC
                     TYSIYVKNNTNGDGEFTLYQSDIQGNEHTISIPEGDLNLDIYVVANYNGNSSQNSDVI
                     NVR"
     gene            complement(8057..8743)
                     /locus_tag="PC512_003192"
     CDS             complement(8057..8743)
                     /locus_tag="PC512_003192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate/glutamate racemase family protein"
                     /protein_id="HDF2442920.1"
                     /translation="MKTIGLIGGMSWESTITYYQVINTVIKERLGGLHSSKCILYSVD
                     FQEIEECQSSGNWEKSAKILADAAIKLQEAGADFIVICTNTMHKVSDKIQESIHIPLL
                     HIADVTATVLREKEIKKVALLGTKYTMEQDFYKNVIINNGIEVLIPNEEDRIIVNDTI
                     FNELCLGIISESSKKAFLSIIDKLGKQGAEAVILGCTEIGLLIKQNDTSIPLFDTTVI
                     HAIEAALSSI"
     gene            8868..10250
                     /locus_tag="PC512_003193"
     CDS             8868..10250
                     /locus_tag="PC512_003193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDF2442921.1"
                     /translation="MPINSFENYPMTWKPKLDNRKPPIYKTLAMLLEEDIKRGNLNPG
                     DKLPPQRELADFLDLNLSTITRAFKLCEEKGLICAKVGKGTFISSDVNVSNTLLYQTE
                     SKDIIELGTVHPPYEQNTYIIDFIKNVLKQPEMDRFLQYMSPSGTYMQKKSIAKWIER
                     NNVYTSEENILLSTGGQNAICATLLGLFKAGDRIATDSLSFSGIKSIAKMIGIQLVPI
                     PQENNEISIEYLESYCKNENIKGIYLIPDYHNPTTHTMSDLSRKKIAKIAKQYNIIII
                     EDAINSIFRDGIQTPIFSLASDNTIYIFSTSKFLCAGLRVAFVVAPKRYIENLENALY
                     NMNLMVSPFTAEIVHRLLYSPIIDKIIEEKRDAIIERNEVADKVLSDYNLIGDKNCSF
                     RWLLLPDELDGKSFEISAKNLGVQVYCAERFSVGNSTVPKAVRICVTAPKDVEELEKG
                     LNIIKSLLKS"
     gene            10652..11920
                     /gene="eam"
                     /locus_tag="PC512_003194"
     CDS             10652..11920
                     /gene="eam"
                     /locus_tag="PC512_003194"
                     /EC_number="5.4.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 2,3-aminomutase"
                     /protein_id="HDF2442922.1"
                     /translation="MNEQTRISLERAAELKSKIDDYIQARKTINRGLEKEEEINKRKQ
                     KILSILNGTEEDWNNYKWQLSNRITDVDTLSKIITLTKKEKEYIKEVGTQFRWAISPY
                     YLSLIDPEDICDPIKLLSIPTHIELEDEQEDLDPMGEEYTNPAGCITRRYPDRLIINV
                     TNECAMYCRHCQRRRNIGQQDSHKSKAIIQESIDYIRENEEIRDVLVTGGDALTLKDD
                     YLEWILSQLKEIPHVDYVRLGTRTLVTMPQRITDEFCNMLKKYHPVYINTHFNHPMEI
                     TKESKEACEKLANAGVPLGNQAVLLNGINNDKFVMRCLNQELLKIRVKPYYIFQSKHV
                     KGTKHFNTSVDDGLEIMEYLRGYTSGMAIPTYIVNAPKGGGKTPLLPQYLVSKGTDYV
                     MLRTWEGKVIKMEDEPAVDIKKLIKEQAQD"
     gene            complement(12013..12369)
                     /locus_tag="PC512_003195"
     CDS             complement(12013..12369)
                     /locus_tag="PC512_003195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442923.1"
                     /translation="MKKALISLLVLSCLLLTAPVNESSYADSQKNVPVSQNTKLTQEQ
                     AKELLVKYNNEVDYIYQGNASDFEALKAKNLNGYVFLPDADGDIGYFVNENTSEIYYF
                     HPSGYLELVNQQQNNK"
     gene            complement(12520..13614)
                     /locus_tag="PC512_003196"
     CDS             complement(12520..13614)
                     /locus_tag="PC512_003196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDF2442924.1"
                     /translation="MQDKKIYLNIVLTVVVSYILIKVIDNYKYFFGVISLLMSLLTPF
                     IIAFVLAYIFNPLVKFLESKLNFKRIYSLLLTYGVLIVILISFILFTVPSIVNSLADL
                     VAQIPTYIDKTEQFLFDLGKSLQSVDPNTLKEYGDKIMSVMPKFSNLLIGSLGGIFST
                     TFSVGKFIVQFLLGFIICFYILLEKEKFLLFTKKVVYISLGKKYGDFIIELCQSLNLN
                     IGKYFTGKILDSFIVGVLSGIGLYFLKSEYALLFGTLMGVMNMVPYFGPVIGMAPVVI
                     INLFSNPTIALTSLIYLIIIQQVEVTFIEPKIVGGQLGLSPFFTILAVTVGGGFFGIP
                     GMILSAPVMGVIKIYFCEFVNRRHDKIQME"
BASE COUNT         5355 a         1727 c         2171 g         4432 t
ORIGIN      
        1 catacttata tatttagtta ttcaaactat tatttcgagg aggtcttgtt gtgaatataa
       61 aagatagatt aagtggatta agaaaattta tggaagaaaa aaatatagat gcctatatga
      121 ttccatcttc tgataatcac caaagtgaat atgtaggaga ttacttcaaa tcaagagaat
      181 ttatatcagg gtttaatggt tcagcaggga cggttattgt gactaaagac gaagctgggt
      241 tatggacaga tggaagatat tttatacagg cagaatctca attagaagga agtacaataa
      301 aattattcaa aatgggacaa gaaggttgcc caactacaga tgaatattta tataaaaata
      361 ttcctgaagg aggaacttta ggatttgatg gtagagttat atctgctaga gaaggagcta
      421 cattagctga aaaattatct aaaaaaggta taaagataga atatcagtat gatttaatag
      481 atagtatatg gccagataga cctgctttat cagatagtaa agcattttta ttagatgtta
      541 aatattgtgg agaaagtttt agctcaaaat tagctagatt aagagaaaaa atgagtgaaa
      601 aaggtacttc tactcatgta ataactactc ttgatgatat agcatggtta ttcaatataa
      661 gaggtggaga tgttaaatat aatccagttg tactttctta tgcagtaata actttaaaag
      721 aagtttatct atttgttgat gaaagtaagt taaatgaaga aatactaaat gaactagcta
      781 aggaaaatgt tcaaataaag ccatataatg atgtgtatga atttgtaaaa aatatagaca
      841 aaactgaaaa agttttatta gatggaacta agcttagtta tacaatttac aataatatac
      901 cttgtgaagt tgagaaagtt gatgagttca atccagtaat gttttttaaa gctcaaaaaa
      961 atgaggtaga attagaaaat ataagaaatt cacatgtaaa agatggtgta gctttcacta
     1021 aatttatgta ctggttaaag aaaaatgtag gtaagatgga aatcactgaa ataagtgcta
     1081 ctcaaaaatt agaggactta agaagagagc aagaaggttt ctttgagcca agtttcaata
     1141 caattgctgc atataaagag catgctgcaa tgatgcacta tagtgcaact ccagagtcaa
     1201 attataaatt agaggcagaa ggattatttt tagtagattc aggtggacaa tattatgatg
     1261 gaactactga tataactagg actacagttt taggacctat aagtgatgaa ttaaaactac
     1321 actttacttc tgtagcaaga ggaatgataa atctttctaa ggctaagttc ttgcatggtt
     1381 gtagaggata taacttagac atactatcta gaagttgcat gtggaatatg ggaattgatt
     1441 atcaatgtgg aactggacat ggtataggat ttgtgctaaa tgttcacgaa gctccaaatg
     1501 gatttagatg gagagtagta cctgaaagat ttgatagtgc agttcttgaa gaaggaatgg
     1561 taactactaa tgaaccaggt atatatatag aaggttctca tggtataaga acagagaatg
     1621 aaattgtagt tagaaaagct gaaaagaatt tctatggtca atttatggaa tttgaagttg
     1681 ttacgttagc tcctattgac ttagatggta tagtaccaga attaatgaat aaggatgaaa
     1741 aagattattt aaactggtat cataagttag tttatgataa aatatcacct ttcttaactg
     1801 atgaagaaag agaatggtta aaagtttaca ctagagctat atagtttgta ctagatacaa
     1861 taaaaatcga ggtattataa tgcctcgatt ttttattgta tattttatta actttaaaaa
     1921 atttttaatt tgataattct actaattttt tattcattat aagtagtata attccaaata
     1981 tcaataaaaa tgatggtatc actatgaaga cttgtaacat accaagttgg tctataatag
     2041 cttgcgtata gccagataat ttatttgctg caaatttgcc taaaaaccaa acacccatta
     2101 ggaatgaaat atacttttca ggcgaaagtt tatttaccat accatacccg actggagaaa
     2161 agcaaatttc tcctatactt tggaatgtta aaaatccaac tacccaaaat acacttgctt
     2221 tgtgaattga attagggtct gttcctgttt gtataactgc tactatcata aacaaaaatg
     2281 ctatggctaa tagtataaaa cctaagctca ttttttttgg cacacttaaa tcgccttttt
     2341 tagtttgaga taattttacc catactaaag cagagatagg tccaagaata acacaaagga
     2401 gaccattgta tgaatctatc catgaagtag gaatttgaaa attgccaaca gtaagattta
     2461 tgtgttcctt tgtatagagt gcaatagaca tagaggcttg gttatatgct atccaaaaaa
     2521 atactgtgaa aaaagctaac accaatatta ctattattct ttttttctca atcaaagtta
     2581 aaggtcttga agctagcatt ttcttatatt ctagtgattt tcttatagac tctctcccgt
     2641 tactagggtc attattcaaa ggtttataaa actttctgtt tccaaatata aagaagaata
     2701 aacctattag aaccgtaatt gatgaaaata aaaatacata tctatatcca tacatactta
     2761 tagataatcc gcttttcata gcaaaccatt cattagcaac taaaccgcat attaaagggc
     2821 caaataaggt acctagatta gtagccatat acgtaataga gaaagctcca tcttttcttg
     2881 ggtcatcatt ggtatataag tttccaacca tagtatgtaa gtttccttta taaaaaccta
     2941 ttcctaatcc agataaaaat atcatgatgt ttatatccat cttactattt gctatgtatc
     3001 ctagaaaata accaattgaa accattagca ttccaagtat aatacagttt ttgggaccta
     3061 aaaatctatc actgacccat ccaccaataa ctggagagaa ataagtccat gctaaaaaag
     3121 atgcaagcat tgatgcggat tctgctggtg ttaaccctaa accacctttg gagacttgtt
     3181 cagctaaaaa caataataat accaatttca taccatagta tgcaagtcct acaaaggtaa
     3241 atattgaaca gcagaaatat aaatctctag gttgtttaag tttttcttgc gtttttaaaa
     3301 ctgacatatg tcgagaacct ccagataaat agtttaacaa aattttacca tactatatga
     3361 gtatatgttt ttttcatata gacgtcaact tgtaagataa tttaattaag tcgaaatata
     3421 tgtaaaaata gtatcatttt tgtgtattca gtaatatttt tttatgataa tatatgttat
     3481 tattatatta aaatacaaac atatttatgg aaaggatatg ccaatttagt agttagattg
     3541 attgtttggc aggtgggatg agctatgata agaaagaaat ctgaattaca agtagaagta
     3601 aaagaaaatt taaatggtgg tataggaaag gttaagcttg aaaacataat acaaaatgaa
     3661 gagcttaaag gaaaaggaag actatttaaa agagtagctt taccagtagg aagttcaatt
     3721 ggtgtgcatg accatacaac agattttgaa gtatattata tactaaaggg aaaaggtaaa
     3781 gtatttgata atggggaatt tgtagaagta aatgagggtg atgtagtgta tacagctgat
     3841 ggcgaaaaac attctataga aaatatagga gaagaagatc ttgagtttgt agcactagtt
     3901 ttatatatgt aaaatatgga ggaggagtca tgacaggcaa gatagaagaa attaaggaca
     3961 agataaatag attttgcaac tccaatttaa atcaagaata caaagatata agctttaaaa
     4021 ttttgcaaaa ccttttagat aataataaag agataattca ttcttctaga gctgatatat
     4081 ggtcttcagc tatactaaat atagttttag aacaaaatct tttatacaat aagaagcatc
     4141 cactacatat aacaaaaaaa gagttttcaa aacaaatagg tgtttcttta aatactataa
     4201 ataataaatc gtctttaata aaagatgttt gtagtattga ctttttaaat caagatacta
     4261 tagctatttc taatgtagaa ttttgggtaa aagagaccaa ttccaaatca aagtctgtag
     4321 atttagattt agaaaagaaa aaaatactat ataaaagata tattaagcta tcacaagatg
     4381 cgaatagtga tattgaatca attagatata tggaggaagc tgtaaatata ggtaaaagta
     4441 tgattactaa agaagataaa gaacttggat tttggaaagg tttatctacc agagcctata
     4501 tgatagcact tgaatccctt gctagaaagt tagaaagtat taataatcta aaggagtcca
     4561 aaaaagtatt agaatattta atagaaatta atcctagtga tgagcaggga ataagataca
     4621 aattattaaa tgtattaatt agattaaatg atagaacttc aataaataaa ttatttgaac
     4681 tttataaaga agaaaaatct gctacatgga tgtacagtaa agctctttat tactttaaaa
     4741 ataaaagtat gtttttggca aatgattcta ttaaggttgc tagaagtaaa aataagtacg
     4801 ttggattata tttgttagat tggcgaaatg cttttggtag agaatttgtt acagaggaag
     4861 aaaaggcaga agctgtctat tactatgatg aaaacatagt gatttggaat gaagttaaag
     4921 gttctatgga ttggctatta aaaaaaatgt tggaattttc ataaaaaaaa ctactcctta
     4981 cttttatata agtaaaagga gtagttttta atttatacat ctagttttaa atcttcaggt
     5041 tttattagac ctttttttct cataaattct gaaatcaaca aagttacaat agcaggaagt
     5101 ataaaattaa gtaaaagtat accaacccac atagatatac ctccttttcc agcactttgc
     5161 atagcagtta ctgttccaaa ttgtccaacc aatccacaag tacccatacc agaaccaata
     5221 ggaatattct ccattttgaa tattgttgta gataatggtc caagtaatat tgaagctaca
     5281 gtaggtggta tccaaatttt ccaatttttt attatattag gtacttgcaa catagatgtc
     5341 ccaagacctt gtgccacaag gccgccaact ccattttctc taaagctcat aacagcaaag
     5401 cctaccattt ggcaacaaca acctacagtt gctgcaccac cagcaagacc acctaaactt
     5461 aacatcatac aaatagctgc actacttata ggtaatgtaa gagctattcc aacaagtgca
     5521 gagactaaag ctcccattat tataggttgc atagttgtag cttgcattat tatatttcca
     5581 aatgaagtca taaaagcaga aacagctgga ccaataagtt cagctacaag tactccaatt
     5641 agtattgtta cagcaggtgt aaccaatata tctatttttg tttcttttga aactaatttt
     5701 ccaacctcta cagcaaaaag tgtagcgaca aatgctccaa caggtcctcc taattcatta
     5761 ccacaagctc caacaagtgc acaagaaaat agtacaagtg gaggtgcttg aagtccatac
     5821 gcaatagcca ctgctatagc tggaccagta acctgtttag caagagggct tataacttca
     5881 gtaaaaagag aaatattgaa attatctcct aatgtattga aaattgttcc aattaaaagg
     5941 gacgaaaaaa gaccgagtgc catataactt agtgcgtcaa taagatacct ttgaacagaa
     6001 atttcaatat tttttctttt agcaaatgat ttgaaatttc tttttttata attgatttcc
     6061 aatttaaaat cctcctcata taatataagt ataatttctt tttaattaat tatataactt
     6121 ttcagctgac aagacaaatg ttatttcact aaaattagac tattgtaata gtaagaaatt
     6181 aacattaatt ttagttttaa attttaaatt tatggtttat aattagtata gggatattct
     6241 gaaatataat aattttccag tttatcccaa tatttaactt aggtagattg cttacaaaac
     6301 aaatgattat atattaggct aaaaggaagt ggatagatga tatttgtaaa aaataagaaa
     6361 tacagaaaaa ttgccataat tatatctatt cctatattgc ttgttgcgca gtactacctt
     6421 tttaaatttg gaatacttag accaatggta aagggagtag aaattgaaat tgtagatggg
     6481 gaatatgtta aagatataga taaatatgta gtaaaattaa atgaaacagt tactttgtct
     6541 acaggtgaat atattaaggt tccttcgtat gctaaaaatc caaatatttg gtttaatgta
     6601 ttggataact cagggacttt aaaaatagat ggaaataaaa tgacagcatt aaaggttggg
     6661 tattcttctg tgggtatcat gaaaaattca agagtattaa aaaaggctac tataaaagta
     6721 gtagacccag aggtagaatc actagatatg gagattaatg gggatttaaa acatgttggt
     6781 gatagtgcta ctatagaaag tacaatagaa gttgattatg ataagtttaa aaaatcatat
     6841 aagccagttt ataagagtag caatgaaaat attttaaaaa tcaaaggaaa taaagtaagt
     6901 gcagttggag ttggtaaagc tacaatatat gctaagtgtg gaaataaaga aattgagaga
     6961 acatttagga ttcaagctag agttgctgaa ataaatatgg atgatataaa aatagaagtt
     7021 gaccagaatg aaaaattgaa accagatata ataacttctc cacctggttt agaaccacca
     7081 aaaatatatt atgagttagt agattcaaaa ttacctgtag aaagagcaat aagtttaagt
     7141 agtaatggaa atgttgtagg gcttagagaa ggtaaagata gggtgagaat aacttgtgga
     7201 gataaatcta aagtaataac agtaacagta gtcaaagaaa ctataacgaa tgactatata
     7261 caaaacttgg ttggttcaca taaaatagta aacaataaag ttattattaa acttgaatgg
     7321 gattatatga aagatgtctt tgattatgat atatatctta aagataagtt gtcaggagaa
     7381 tcatttaaga aaattaaatc tataactata aatgaaagtg atttaggtaa gtctaacaag
     7441 gtatatgcaa ctatagaagt agatatgaag ggtaatcaaa atatagattt tgatatttat
     7501 gtcataggta aaaaggattc agatacaact aagccaagta atgtaataaa tattaccaat
     7561 ggaaatggaa attcaaataa tgataataat attaaagata tgagggtaga aaatatatca
     7621 gctaatgttg atagagataa taatgtcatt agagttaact ggagtagtat atctcataag
     7681 gactgtactt acagtatata tgtaaaaaat aatactaatg gagatggaga atttactcta
     7741 tatcaaagtg atatacaggg aaatgagcat actataagta ttcctgaagg agatttaaat
     7801 ctagatattt atgttgttgc aaattataat ggaaatagct ctcaaaatag tgatgttata
     7861 aatgtaagat agatttgtat acaaattgaa agtgttgagt ttatttaaat attaaattaa
     7921 gaaaaaggat agtatagggt aattatacta tccttttttg ttacaatata taggtttaaa
     7981 atctctagta atataaatta taaaaagtct tatttacaca aatctataga tatttttttt
     8041 attaatcaat attgtcttaa attgaactta gtgcggcttc tattgcatgt attactgtcg
     8101 tatcaaatag tggaatagaa gtgtcatttt gtttaattaa aagacctatt tctgtacatc
     8161 ctaatataac agcctctgca ccttgtttgc caagcttatc tataatagat aagaaagctt
     8221 tttttgaaga ttcagatata attcctaagc aaagttcatt aaatattgtg tcatttacta
     8281 ttatacggtc ttcttcattt ggaattaaga cttcaattcc attattaata attacatttt
     8341 tataaaaatc ttgttccatt gtatatttag tacctaataa ggccactttt tttatttctt
     8401 tttcccttaa taccgtagca gttacatctg ctatgtgaag taatggaata tgtatacttt
     8461 cttgtatttt atctgatacc ttatgcatag tattagtaca gataacaata aaatctgccc
     8521 ctgcctcttg taatttaatt gcagcatcag ctaaaatttt ggcgcttttt tcccaatttc
     8581 cactagattg gcattcttca atttcttgaa aatctacact gtaaagtata catttagaag
     8641 agtgtagtcc acctaatctt tcttttatta ctgtattaat aacttgataa tatgtaatgg
     8701 tactttccca actcatacca ccaattaagc ctatagtctt catattatac ctctcttatt
     8761 tatttatttt gaaatagcta tttacaaata caagtatagc atctaaaata gaagcataca
     8821 ataataaaat tgtatggagt acaattataa ttaagaggag taattatatg ccaataaatt
     8881 cttttgaaaa ctatcctatg acatggaaac caaagttaga taaccgaaaa ccaccaatat
     8941 ataaaacttt agcaatgtta ttagaagaag atattaaaag aggaaattta aatcctggag
     9001 ataaattgcc tccacaacgg gaattagcag attttctaga tttaaactta agtacaataa
     9061 cacgagcatt taaactttgc gaagaaaagg gactaatatg tgcaaaagtg ggaaagggaa
     9121 cattcatttc ttctgatgta aatgtaagta atacattatt atatcaaacg gaatcaaaag
     9181 acataattga gttggggaca gttcatcctc cgtatgagca aaatacatat attattgact
     9241 ttattaaaaa tgtactaaaa caaccagaaa tggataggtt tttacaatac atgtctccat
     9301 ctggcacata tatgcaaaaa aagtcaattg caaaatggat agaaagaaat aatgtataca
     9361 ccagtgaaga aaatatatta ttatctacag gagggcaaaa tgctatatgt gcaactttac
     9421 taggattatt taaagctggt gatagaattg ctacagattc tttaagtttt tctggaatta
     9481 agtcaatagc taaaatgata ggtattcaat tagtcccaat tcctcaagaa aataatgaaa
     9541 tatcgattga atatcttgaa agttattgta aaaatgaaaa tataaaaggc atatatctta
     9601 taccagatta tcataatcca acgacacata ctatgtctga tttatctcgt aaaaagatag
     9661 ccaagatagc aaagcaatat aatataataa ttattgaaga tgctataaat agcattttta
     9721 gagatggtat acaaactccc atattttctt tagctagtga taatactata tatattttta
     9781 gtacatctaa atttttatgt gctggtctta gagtagcatt tgtagttgct ccaaaacgat
     9841 atatagaaaa tttagaaaat gcactatata atatgaatct aatggtttct ccatttacag
     9901 cagaaatagt acaccgttta ttatattctc ctattataga taaaattata gaagagaaaa
     9961 gagatgcaat tatagaaaga aatgaagttg ctgataaagt tttgtcagat tataatttga
    10021 ttggtgataa gaattgcagt tttcgttggt tacttcttcc tgatgaattg gatggaaaat
    10081 catttgaaat ttctgcaaaa aatctaggag ttcaagtata ttgtgccgaa cgattttcag
    10141 taggaaactc tacagttcca aaagcagttc gtatttgtgt aacagctcca aaagatgtag
    10201 aagaattaga aaaagggctt aatataataa agtcacttct taagagttaa atttatttta
    10261 ctattattta attaaataaa taaaaaggcg gagaaattta ttataataaa cctccgcttt
    10321 tattatttaa tgaaatactt tactttttat taaaaaattt aattttaata atcttgaaaa
    10381 tataatcgtt ttatggtaaa ataattctta aaaatagaaa aaattaatca tttgttaaaa
    10441 aaaatgcata atttattgta atttattgac gaaggttgaa aaatattcat aaatgtgcga
    10501 aataacagaa aaaatgcaaa aattaattca atttcatttg ttataaaatc tatatggcaa
    10561 aattaaatct gcctatcaga atgatataaa cacatcagaa aggaggacgc tatcaaataa
    10621 tacaagtagt taactttgat agcaaaaaat tatgaatgaa caaactagaa tatccttaga
    10681 gagagctgct gaattaaaat caaaaattga tgattatatt caggctagaa aaacgattaa
    10741 cagaggtctt gaaaaagaag aagagataaa taaacgaaaa cagaaaatat taagtatctt
    10801 aaatggaact gaagaggatt ggaataacta caaatggcaa ttatcaaata gaataacaga
    10861 tgtagatact ttatcaaaaa ttataactct aactaaaaaa gaaaaagaat atataaaaga
    10921 ggttggtact caatttagat gggcaatatc tccatattat ttgagtctta tagacccaga
    10981 agatatatgt gacccaataa aattactgtc tataccaaca catatagagt tggaagatga
    11041 gcaagaagat ttggacccaa tgggagaaga gtatacaaac ccagcaggat gtataactag
    11101 aagatacccg gatagattaa taataaatgt aacaaatgag tgtgctatgt attgtagaca
    11161 ctgtcagaga agaagaaata ttggacaaca agattctcat aagtcaaaag ctattatcca
    11221 agaatctata gactatatca gagaaaatga agaaataaga gatgtactag taactggtgg
    11281 agatgctctt acattaaaag atgattattt agagtggatt cttagccaac ttaaagagat
    11341 accacatgtt gattatgtta gattaggtac taggactctt gttacaatgc cacaaagaat
    11401 tacagatgaa ttttgcaata tgctaaaaaa atatcaccct gtatatataa atactcattt
    11461 taatcatcca atggaaataa ctaaggaatc taaagaagct tgtgaaaagt tagcaaatgc
    11521 aggcgttcca ttaggaaatc aggcagtatt attaaatgga ataaataatg ataaatttgt
    11581 aatgagatgt ttaaatcaag aattactgaa aataagagta aaaccttatt atatattcca
    11641 aagtaaacat gtaaagggaa caaaacattt caatacatca gtagatgatg gtcttgaaat
    11701 catggagtat ttaagaggat atacatcagg aatggctata ccaacatata tagtaaatgc
    11761 tccaaaagga ggaggaaaga ctcctttgct tcctcaatac cttgtatcaa aaggaacaga
    11821 ttacgttatg cttagaacat gggaaggaaa agttataaaa atggaagatg aacctgctgt
    11881 agatataaag aaacttataa aagaacaagc acaggattaa aaaaatattt aaagtttata
    11941 aaaagaaaca actttaaaat aaaaagaaaa tggatgtcaa atttatatca atttgcatcc
    12001 attttttatt agttatttat tattttgttg ttgattaact aattcaagat atccacttgg
    12061 gtggaagtaa tatatctcag aagtattttc atttacaaag taaccaatat caccatctgc
    12121 atctggtaaa aatacataac cattaagatt tttagctttt aatgcttcaa aatcactagc
    12181 atttccttga tatatgtaat caacttcatt gttgtatttt actaaaagtt ctttagcttg
    12241 ttcttgagtc aatttagtat tttggcttac aggaacattc ttttgagaat ctgcataaga
    12301 agattcattt actggtgcag ttaataacaa acaagataaa actaataaag atataagtgc
    12361 ttttttcata ctaaaaccct ctttcatgtt taattatata agattcatta cttaataata
    12421 ttgtatgttt cctataatta aatattacca ttaaagagaa taatattaca gttacacagc
    12481 tgtaactttt gattacaaaa tcgtaattaa attgtatttt tattccattt gtattttatc
    12541 atgtctacga tttacaaact cacagaagta tatctttata acgcccatca caggagcaga
    12601 tagaatcata ccaggtatac caaagaatcc tccaccaaca gtaactgcta ggattgtaaa
    12661 gaatgggcta agacctagtt gtccacctac gatttttggc tctataaatg taacttcaac
    12721 ttgttgaatt attattaagt aaattaaaga agttaaagca attgttggat tggagaataa
    12781 attaattatt acaactggtg ccatacctat tactggacca aaatatggaa ccatattcat
    12841 gacacccata agtgtaccaa ataatagtgc atattcagat tttaaaaagt aaagaccaat
    12901 tccagaaagt actccaacta taaaagaatc taaaatctta cctgtaaagt atttaccaat
    12961 atttaaattt aagctttgac atagttctat tataaagtct ccatattttt tacctaagga
    13021 aatataaact actttttttg taaacagtaa gaatttttct ttttctaata atatatagaa
    13081 acaaattata aaacctaaaa gaaattgtac tataaatttt ccaactgaaa atgtagtgct
    13141 aaatatccca ccaagtgaac caataagcaa gttactaaat ttaggcatta cactcataat
    13201 tttgtcacca tactctttta atgtattagg gtcaactgat tgtaaactct tgcctaagtc
    13261 gaataaaaac tgctctgttt tatctatgta tgtaggaatt tgagcaacta aatcagctaa
    13321 actatttact atggatggaa ctgtaaataa tataaacgaa attagtataa ctatgagtac
    13381 accataagta agaagtaacg aatatattct cttaaaattt aatttacttt ctaagaactt
    13441 tactagtggg ttgaatatat atgctaatac aaatgctatt ataaatggtg ttagtagtga
    13501 cattaataaa cttatcactc caaaaaaata tttgtaatta tcaataactt taatcaagat
    13561 atatgaaaca actacagtga gtacaatatt tagataaatt tttttatctt gcaaaataac
    13621 acaacctttc ttatatttat taaatttaga tatacttaaa tctaagttaa agttaatatt
    13681 tatag
//
LOCUS       DAMJVG010000097        13297 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.100, whole genome shotgun sequence.
ACCESSION   DAMJVG010000097 DAMJVG010000000
VERSION     DAMJVG010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13297)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13297)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13297
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.100"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            149..2008
                     /locus_tag="PC512_003197"
     CDS             149..2008
                     /locus_tag="PC512_003197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF2442925.1"
                     /translation="MKRFLRRIILVLFILLIFISFISIKLIHNVGDYGKLINYVGIVR
                     GASQRLTKLEMNHQPNDELIEYIDEILQELITGHGDYGLVITDCNEYNEDLLLLEKKW
                     EDLNIEIKKVRMKEQNNQLLSISEEFFSLANDTVFKIENFSKEKSNYLMTLIIIISII
                     GILACIILILQYSKKMVRLEKLNVDLKNIAYKDELTGVNTIEKFKLDANQNICIHKDK
                     KFAVFYIDFENFKYINDIFGYDYGDMILKRYANLMMNDIGKYEIFAREIADRFVALRC
                     YVDKEDLVVRQRDVDNELINITNEIKNKHSITVVSGICCIEDVNEKLSIDGLINRANF
                     AQKTVKNKPGTNYAFYNDSIRKKMIEENTIKSRIHEAIEKREFIVYLQPKVNLHSQKI
                     NCAEALVRWLTPDKGIISPAIFIPVLEKNFFIALVDKYVFEEVCKWIRKRLDENKPFV
                     QISVNVSRIQFYNTKFVETYSNIQNKYRIPKNTIEIEFTESVAFENQKHLLEIIHDLH
                     ENGFTCSLDDFGKGYSSLSVLKDLPFDVLKLDSMFFKASLDKDKEKIVIKNIVHMLKE
                     LNITTVAEGIECKEQVEFLRDIGCDLVQGFVFYKPMPILEFEKILDKEFVYNS"
     gene            complement(2300..2899)
                     /locus_tag="PC512_003198"
     CDS             complement(2300..2899)
                     /locus_tag="PC512_003198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HDF2442926.1"
                     /translation="MAIELKKGQKINLTKKENSDLGEILVNLNWNQKVQKKGFFGSLR
                     SSNIDLDLGCLFEMKNGVKGAVQALGNAFGSLDNPPFAQLDGNDRTGSNTQGENLRIN
                     GNKIKDIKRILIYAFIYEGVANWSEADGIVTIKQKQDSDLVVKLDEHKNGYNMCSIAL
                     IENVNDETFSVEKVVKYFKGHREMDTEFHWGLKWVAGRK"
     gene            complement(3002..3799)
                     /locus_tag="PC512_003199"
     CDS             complement(3002..3799)
                     /locus_tag="PC512_003199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDF2442927.1"
                     /translation="MKFKKLLCLLLCLVLTLAVVGCSKAKDDKKIVVGATLVPGGELL
                     EELKPLIKEKGYTLEVKNFDDYILPNEALNNGEIDANLFQHEPYLKEAVKAKGYKIMA
                     GKKLYVCPAILYSYKIKSVDEFKKGDTIAISNNPSSCSKNLRYLESIGLLTLPKGDGL
                     VSPKDIIENPKGIQFKELDIAQIPSSLPDVTAAFIDTTYAVPAGLDAKKNGIYTAPIN
                     DEYANLLAFRTEDKDSEKIKVLQDVLTSDKARSLIEEKYKGIVIPTF"
     regulatory      complement(3912..4017)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(4109..5095)
                     /locus_tag="PC512_003200"
     CDS             complement(4109..5095)
                     /locus_tag="PC512_003200"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HDF2442928.1"
                     /translation="MLLIYNEKTNPYFNLAMEEYLLKNFDEDLFILWRNEPSIIVGKN
                     QNTLSEINLEYIKEYSIPVVRRQSGGGAVFHDLGNINFTFIACNNNNFSDFRRFTQPI
                     IDLLKTLDVNAEFSGRNDLLIDGKKFSGNAQYNYKNKVMHHGTLLFSSEINDLSKALK
                     VKPIKFEGKGIKSVKSRVTNISEHLHSKMDILEFKDAIMDYLSKTNTDNTNYCLSEHD
                     IKQIEKLTKSKYETWDWNFGNSPKYTLSNELKYSGGNVEFNLNVDKGIITSIKFFGDF
                     FGKCDVAFVENKLIGIRHEENALRNTLDSIEINDYFLGADTDILVSGILGVK"
     gene            5579..7309
                     /locus_tag="PC512_003201"
     CDS             5579..7309
                     /locus_tag="PC512_003201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC family protein"
                     /protein_id="HDF2442929.1"
                     /translation="MRNKKINIIFLTTIMFIMSTVMVFAEEDIDTIALANAEKFGILT
                     LIPPLVAIILAFITKNVIISLLIGILSGSFIIKASGINVFATFIQAFLDLVDRALVSL
                     ADPWNAGIILQVLAIGGVINLVAKMGGAKAIAEALAKRAKSAKGTQLITWFLGLLVFF
                     DDYANSLIVGPMMRPVADKMKISREKLAFIIDATAAPVAGLAIISTWIGLEVGLIHDA
                     FESISIDVDAFGIFLNTIPFRFYNILILAFIVISALLLKEFGPMRKAEIKSRSRKISI
                     DLDEGVEELDDLAPKNGVKLSVWNAIIPIGTLIIVALASFYYSGYTSIMGGDDKALIQ
                     LFTNSPYSFEAIKEAFSASDASRALFQSALVASLVAIIMAVVKKIFTISEAIDVWIDG
                     MKSLVITGVILILAWSLSSVIKELGTAKFLIHLLSGSLPPFLLPSLIFGLGAIISFAT
                     GTAYGTMGILMPLAIPLAYSLNPDMSYVIVSTSAVLTGAIFGDHCSPISDTTILSSMG
                     AGCNHIDHVNTQMPYAIFTAVITIVFGYIPAGLGLPIYIVLPVAIAAIFVGIQIIGKK
                     VDEAEIELVE"
     gene            7419..7499
                     /locus_tag="PC512_003202"
     tRNA            7419..7499
                     /locus_tag="PC512_003202"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7453..7455,aa:Leu,seq:tag)
     gene            7834..8349
                     /locus_tag="PC512_003203"
     CDS             7834..8349
                     /locus_tag="PC512_003203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HXXEE domain-containing protein"
                     /protein_id="HDF2442930.1"
                     /translation="MEKYIWLFPLLFIFHDMEEIIGFGIWLKKNKSMLDKKYPFISKV
                     YENYSTEGMAFAVFEEFILCIIFCILTVITENQYVYLLWLGSFIAYTLHLVIHIGQSI
                     IIRKYIPSLITSIICLPISIWCISKSIYIVDCEMSTTILYSIIGIIIVALNLKFAQSL
                     IGKFTKWMSNI"
     regulatory      8841..8945
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            9155..11629
                     /gene="gcvPA"
                     /locus_tag="PC512_003204"
     CDS             9155..11629
                     /gene="gcvPA"
                     /locus_tag="PC512_003204"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase
                     subunit GcvPA"
                     /protein_id="HDF2442931.1"
                     /translation="MNELKRVSLYNIHKELGAKLVEFAGWEMPLEYEGINKEHEKVRK
                     SAGIFDVSHMGEVQIKGAESEKFIQNLVTNDISALKINDIIYTPMCYENGGVVDDLLI
                     YKFGEEDYLLVINAGNIDKDVAWIIKQSEGYNVDIKNISSEVSQLAIQGPKAEEILQK
                     ITDIDLNSIKFYKSIPSTKVCGCPCLVSRTGYTGEDGFEIYCKNKYVEIIWNEVLKVG
                     GEDICPAGLGCRDTLRFEAALPLYGHEINEHISPIEGGLSIFVKTNKESFIGKSILSK
                     EKESGAKRKLVGFEMQGKGMPRNGYDIRIGDKTVGFVTTGCASPTTGKILGMGIIDSE
                     YAKVGNEIGIAIRKKVVPAVIVKKPFYKKQYKKDNIILNKENKFSYIPATSEDKSKML
                     KVVGLNSVDELFSDIPEEVKLKRDLNLEIGKSELEVSKIVKRLSEENLSLEDLTCFLG
                     AGAYDHYIPSIIKHITSRSEFYTAYTPYQAEISQGTLQVVFEFQSMIAEITGMEIANA
                     SMYDGATAAIEACIMAMNQTRKSKIVVSKTIHPETLSILRTYLQYKDCEIVEIDFCNE
                     YGTTDIEKLKASVDKDTACVLIQTPNFFGIIEEMEEIEKITHENKAMLIMSVDPISLG
                     VLKTPGEIGADIVVGEAQSLGNPLNFGGPYVGFLASKSKYTRKMPGRIVGQSLDVEGK
                     IAYVLTLQTREQHVRREKATSNICSNQALNALVASIYIATMGKEGFKEVGMQSMKKAH
                     YTYNKLVQTGKYKPIFKGKFFKEFAVQGNLNIETINDKLLEENILGGYNLEYNYPELK
                     NSTLLCVTEKRSKEEIDKLVGIMEGL"
     gene            11629..13086
                     /gene="gcvPB"
                     /locus_tag="PC512_003205"
     CDS             11629..13086
                     /gene="gcvPB"
                     /locus_tag="PC512_003205"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase
                     subunit GcvPB"
                     /protein_id="HDF2442932.1"
                     /translation="MKEYNSLLIDISKKGRKAYSLPKLDIDDIKIENMIDQDMARQSE
                     LNLPEVGELELVRHYTLLSNKNFGVDTGFYPLGSCTMKYNPKINEDMAALPNFTGMHP
                     YQSSDTAQGSLSLMYDLSRRLAEITGMDEVTLQPSAGSHGEFTGLMIIKAYHENRGDH
                     KRTKVIIPDSAHGTNPASAAMANFDVIQIASDKNGAVDINALKEVLNDEVAALMLTNP
                     STLGLFEKNIKEIATLVHEAGGLLYYDGANMNAIMGITRPGDMGFDVVHLNLHKTFST
                     PHGGGGPGAGPVGVKKELVPFLPIPVIERKEDKYVLNYDREKSIGKIKNFYGNFGVLV
                     RAYTYILTMGRDGLKEASEMAVLNANYIKESIKDDYILPIDTLCKHEFVLGGLPRGEA
                     NIKTIDIAKRLLDYGYHPPTMYFPLIINEALMIEPTESESIETLDSFIEAMKSVAKEA
                     KEEPELLKTAPHNTLVKRVDDARAVKKPILTWSQR"
BASE COUNT         4982 a         1576 c         2197 g         4542 t
ORIGIN      
        1 gaggactcta aagatgaact atgtaaaaca aggtttatat attctaattg tatagaaaat
       61 ttattgtaaa cgcatgtata ttattagaaa aaatagtttg aaggtattca ataaacataa
      121 aaaacaatat aggggataaa ggtgttttat gaagagattt ttgaggagaa ttatcttagt
      181 tttatttatt ttgttgattt ttataagttt tatttctatt aaattaattc ataatgttgg
      241 agattatgga aaattgatta attatgttgg gattgttcgt ggagctagcc aacgtctaac
      301 taaactagag atgaatcatc aaccaaatga tgaattaata gaatatattg atgaaatcct
      361 acaggagttg attacagggc atggagatta tggtttagta atcactgatt gtaatgaata
      421 caatgaggac ttacttttat tagaaaaaaa gtgggaagat ttaaatattg aaattaaaaa
      481 agtaagaatg aaagaacaga ataaccagtt attaagtata agtgaagagt ttttttctct
      541 tgcaaatgat acagtgttta aaatagaaaa cttttctaaa gaaaaaagta attacttaat
      601 gactttaata ataattatat ctattatagg tatattagca tgtatcatat tgattttaca
      661 atatagtaaa aaaatggtta gactggaaaa attaaatgta gatttaaaaa atattgcata
      721 taaagatgaa ctaacaggag taaatactat agaaaaattt aaattggatg caaatcaaaa
      781 tatttgtata cataaggata agaaatttgc tgtattctat attgattttg aaaactttaa
      841 atacattaat gatatatttg gatatgatta tggtgacatg atactgaaaa gatatgctaa
      901 tcttatgatg aatgacatag ggaaatatga aatatttgca agagaaattg cagatagatt
      961 tgttgcgtta agatgctatg tagataagga agatttagtg gtaagacaac gagatgtaga
     1021 caatgaacta attaatataa caaatgaaat taaaaataaa catagtatta ctgttgttag
     1081 tggaatttgt tgtattgaag atgtaaatga aaaattaagt atagatggtt taataaatag
     1141 agcaaatttt gcacaaaaaa ctgttaagaa taaaccaggt actaattatg ctttttataa
     1201 tgacagtatt cgtaaaaaaa tgattgaaga aaatactatc aagagtagaa tacatgaagc
     1261 tattgaaaaa agagaattta tagtttattt acagcctaaa gttaatttac atagtcaaaa
     1321 aataaattgt gcagaagctt tagttcgttg gcttactccg gataaaggta ttatatcgcc
     1381 agcaatattt attccagtac ttgagaagaa tttttttatt gccttagtag ataagtatgt
     1441 ttttgaggag gtttgtaaat ggattagaaa gaggttagat gaaaataaac cttttgttca
     1501 gatatcagtt aatgtttcaa gaatacaatt ttataacact aaatttgtag aaacttattc
     1561 caatatacaa aataaataca ggatacctaa aaatactata gaaattgaat ttacagagag
     1621 tgttgctttt gagaatcaaa aacatctttt ggaaattata catgatttgc atgaaaatgg
     1681 atttacttgt tctttagatg attttggaaa aggttattcg tctttaagtg ttttaaaaga
     1741 tttaccattt gatgttttaa agcttgattc tatgtttttc aaggctagtt tagataaaga
     1801 taaagagaaa atagtaataa aaaatattgt acatatgtta aaagaactta atatcacaac
     1861 tgttgctgag ggcattgaat gcaaggaaca agttgaattt cttagggata ttgggtgtga
     1921 tttagttcag ggatttgtat tttataaacc aatgccaata ttagaatttg aaaaaatatt
     1981 ggataaagag tttgtttata atagctaaaa tgtactttat aaaatatgaa ctaattaagt
     2041 aaaattattt tgtactgaat aaatttttac tttatttaca gaataatgat tatttacaga
     2101 aaagcgcgaa aagtgtattc ctttaagtgt gggatggata gcacaaatag aggagaaaaa
     2161 atattggcca tataagaatg cataataata taaatatttg aaaggtcagc attatataaa
     2221 aattaaaaag aaaataaata atttttctat aaaaaagaga ctatgagaaa atttactcat
     2281 agtctcctaa ataatgtatt tattttcttc ctgcaaccca ttttaatccc caatgaaatt
     2341 cagtatccat ttctctatga cctttgaagt atttaactac tttttcaaca ctgaatgtct
     2401 catcatttac attttctatc aatgctattg aacacatatt atagccattt ttatgttcat
     2461 caagtttgac aactaagtct gaatcttgtt tttgtttgat tgttacaatt ccatcagctt
     2521 cagaccagtt agctacacct tcgtatataa aagcataaat aagtattctt tttatatctt
     2581 ttattttatt accatttatt cttaaatttt ctccttgtgt attacttcct gttctgtcat
     2641 ttccatctaa ttgagcaaaa ggtggattgt ctaaactacc aaaggcattt cctaatgctt
     2701 gaacagctcc ttttacacca tttttcatct caaataggca acccaaatct aaatctatat
     2761 tactgcttct taaagagcca aaaaaaccct ttttttgtac tttttgattc caatttaaat
     2821 taactaagat ttcacctaaa tcgctatttt ccttttttgt aaggtttatt ttttgtccct
     2881 tttttaattc tatagccata gtaatcttcc tccacaaaca tagatttatt taaatggtag
     2941 cacttaataa gtcaatattc aacaagatta gaataataat attaaaatta tactaaatat
     3001 actaaaaagt aggaatcaca atacctttgt atttttcttc aattaagctt cttgctttat
     3061 ctgatgtaag aacatcttgt agaactttaa tcttttcact gtctttatct tcagttctaa
     3121 atgctaaaag atttgcatac tcgtcattta taggagctgt ataaattccg tttttcttgg
     3181 catcaagacc agcaggtaca gcataagtag tatctataaa tgcagcagtc acatctggaa
     3241 gagaagatgg aatttgagca atatctaact ctttgaattg tattcccttt ggattttcta
     3301 ttatgtcctt aggactaact aatccatccc ctttaggtaa cgttaaaagt ccaatacttt
     3361 caaggtatct aaggttctta gaacaagaag atgggttatt gcttattgca attgtatctc
     3421 cttttttaaa ttcatcaaca gattttatct tataagagta aagtattgct gggcatacat
     3481 atagtttttt accagccatt attttgtaac ctttggcctt aacagcttct tttagataag
     3541 gttcatgttg aaatagattt gcatcaattt caccattatt taaagcttcg tttggaagta
     3601 tgtaatcatc aaagttttta acttctaaag tatatccttt ttctttaata agtggtttta
     3661 attcttctaa taactctcct cctggaacta aagtagcacc aacaacaatt tttttatcat
     3721 ctttagcttt agaacatcca accacagcta aagttaatac tagacataat aacaaacata
     3781 ataatttttt gaatttcata taaattccct cctgaatata attgattagt taaaaataaa
     3841 ataccattct ttatcacact gcaaaataaa aataagcctg agtttaaact caggctttaa
     3901 aagctaattt agactcatct ttcagtataa tactgcagga tttagcacca atgtatataa
     3961 aaatatactg gttgctgggt ttcatagggc cagtcccttc accactctgg ataagaagta
     4021 tcaattttta attatgttat aaatattatc atgatttttt acgtctgtaa acataatttt
     4081 ataaatattt taaaatcttt aatgtatttt atttaacacc taaaattcca gaaactagaa
     4141 tatcagtatc agcacctaag aaatagtcat ttatttcaat agaatccaga gtatttctca
     4201 aagcattttc ttcatgcctt ataccaataa gtttattttc tacaaatgca acatcacatt
     4261 ttccaaaaaa atctccaaaa aattttatac tagttattat gcctttatca acatttaaat
     4321 taaactcaac atttccacca gaatatttta attcatttga aagagtatat tttggtgaat
     4381 taccaaaatt ccaatcccaa gtttcgtatt ttgatttagt aagcttttct atttgtttta
     4441 tatcatgctc actcaaacaa taattagtat tatcagtatt tgttttagaa agataatcca
     4501 ttatagcatc tttaaattct aatatgtcca tttttgaatg taaatgttca cttatattgg
     4561 ttacacgaga ttttacagat tttattcctt ttccttcaaa ttttataggt ttaaccttta
     4621 atgcttttga gaggtcattt atttcagatg aaaataaaag agtaccatga tgcattactt
     4681 tgtttttgta gttgtattga gcatttccag aaaatttctt gccatctata agaaggtcat
     4741 ttcttccaga aaattcggca ttgacatcta gtgttttaag taaatctatt atgggctgag
     4801 tgaatcttct gaaatcacta aaattattat tgttacaagc tataaatgta aaatttatat
     4861 ttcccaaatc atgaaataca gctccaccac cagactgtct cctaacgaca ggtatagaat
     4921 attcttttat atattctaaa tttatttcag aaagtgtgtt ttggtttttt ccaacaatta
     4981 tagaaggttc attcctccat aaaataaata agtcttcatc aaaatttttt agaagatatt
     5041 cttccattgc taaattaaaa taagggtttg ttttttcatt ataaattaat aacattaaag
     5101 tagttcctcc atagaattga taaaattttt attatgaata caattaattt tataattcga
     5161 caataatata aaaactcctt taaattagaa attttaaaaa ctaccttgca aagtttaaat
     5221 aaataatata tactcaaaat atgtttaata aaagtgaata gaagggtaga ggcgcaataa
     5281 tctatcagta ctaataagga gttaagcaca gagatttatt aggaaaggag atattgccga
     5341 agttttataa tcgatgcttt aagattatat tgctgggggt acatagaaaa tatgtacaac
     5401 tgtcacaggt ttatttgtgg tgagctatca tttaaggaat tatattatat ttatttttac
     5461 tattgttgat atattgtaat gtttaagcct tgagtgttta ccactcaagg cttttttagt
     5521 tttattgtaa cataataccc tgtacagttc acaaaattaa aaggagaggg agatttatat
     5581 gaggaacaaa aaaattaata ttatttttct gacgacaatc atgttcataa tgtcaacagt
     5641 aatggttttt gcagaagaag atatagacac tattgcacta gccaatgcag aaaaatttgg
     5701 gattttaact ttaataccac cattagttgc tataatactt gcatttataa ctaaaaacgt
     5761 aataatttct ttacttatag gtattctttc tggtagtttt ataattaaag ctagtggtat
     5821 taatgttttt gcgacattta tacaggcatt tttagattta gtagacagag ctttagtatc
     5881 tttagcagac ccttggaatg cagggataat actacaggtt ttggcaattg gaggagtaat
     5941 aaatcttgtt gctaaaatgg gaggagctaa agctatagct gaagcacttg ctaaaagagc
     6001 aaagtcagca aaagggacac agcttataac atggtttttg gggcttttag tattctttga
     6061 tgattatgcc aattcactaa tagtaggtcc tatgatgaga cctgttgcag ataaaatgaa
     6121 aatatcgaga gaaaagctag catttataat agatgccaca gcagcaccag ttgctggttt
     6181 agctataata tctacatgga taggtcttga ggttggttta atacatgatg cttttgaaag
     6241 tataagtata gatgtagatg catttggtat atttttaaat acaataccat ttagatttta
     6301 caatatatta atattagctt tcattgtaat atcagcatta ttattaaaag aatttggtcc
     6361 aatgagaaaa gctgagataa aatctagaag tagaaaaatt agtatagacc ttgatgaagg
     6421 cgtagaagag ttggatgatt tagctccaaa aaatggagta aaattgagtg tatggaatgc
     6481 tataatccca ataggaacat tgataatagt tgcattagca tcattttatt atagtggata
     6541 tacatctata atgggaggag acgataaggc tctgatacaa ctatttacaa attctccata
     6601 ttcttttgaa gcaataaaag aagcatttag tgcatctgat gcatctagag cattattcca
     6661 gtctgcactt gttgcaagtt tagttgctat tataatggct gtagtaaaaa agatttttac
     6721 aatatcagaa gcaattgatg tttggataga tggaatgaaa agtttagtaa tcactggtgt
     6781 aatattaata cttgcatggt cattaagttc agtaataaaa gagttaggta cagctaaatt
     6841 tttaatacac ctattatcag gttcactacc accattctta ttaccaagtt taatatttgg
     6901 tttaggagca ataatatctt ttgctactgg aacagcttat ggaacaatgg gtatacttat
     6961 gccacttgca attccattag catactcatt aaatcctgat atgtcttatg taatagtaag
     7021 tactagtgca gttttaacag gtgcaatatt tggagaccat tgttctccaa tttcagatac
     7081 aacaatactt tcttcaatgg gagctggctg taatcatata gaccatgtta acactcaaat
     7141 gccatatgct atatttacag cagtaatcac tattgtattt gggtatatac cagctggact
     7201 tggattgcca atatatatag tattaccagt ggcaatagct gctatatttg taggtattca
     7261 aataattggt aagaaagttg atgaagcgga aatagaactt gtagaataaa gatataaata
     7321 agtttcacct tttattatca ctattttgtt agtttttaga taattttaaa aagttattga
     7381 aaataatggc gaaatatagt aaaataaaag agtgataagc ggatgtggcg gaattggcag
     7441 acgcactaga cttaggatct agcgccattg gcgtgggggt tcgactccct tcatccgcac
     7501 tttacagtac ttaattgtac tgaaaaaaac tggggttgct ggctttcgga gtgggctatc
     7561 ccgtttttat ttttttgtat atataataga ttggcacttt agtataaggt gcttttttta
     7621 taggcaaaaa cagtacattt atttctgttt tattatcatt catctattag aatatacttt
     7681 agttaagaat gtgttaataa gcagtgttca cattcttgat aaaatgtgga ataatatgta
     7741 tttttactaa gacggaaatg aaataattaa accattaaat aatattataa gatgatgaat
     7801 aagtagataa atcaaatttt gtaggaggat attatggaaa aatatatatg gttgtttcca
     7861 ttacttttta tttttcatga tatggaagag ataataggtt ttggaatatg gcttaaaaaa
     7921 aataaatcaa tgcttgataa gaagtatcca tttatcagta aagtttatga aaattatagt
     7981 actgaaggca tggcatttgc tgtgtttgaa gaatttattt tatgcattat tttctgtata
     8041 cttacagtta taacagagaa tcagtatgta tatctactat ggttaggtag ttttatagca
     8101 tataccttac atttggtaat tcatataggg cagtcaatca taataagaaa atatatacct
     8161 tcacttatta ccagtatcat atgcttacca ataagcattt ggtgtataag taagagtatt
     8221 tatatagttg attgtgaaat gagtacaaca attctgtaca gtataattgg cattataatt
     8281 gtagcattga atttaaagtt tgcacagtcg ctgattggaa aatttacaaa gtggatgtca
     8341 aacatataaa ttttagttta ttggacagtt caaggaatca gaaattggaa ttttatagta
     8401 ttaatatttt atggtattaa tataatgtat aaaattttat agcaatgtat ttcataagta
     8461 taaagtgact agaattttaa gaaatataca aattctataa aaactaaata atttcaagta
     8521 tattttaaaa atcttatttt tcacaagttt aaaattgtaa acgatttcat caagtctatg
     8581 aatatacttt taacatgtta tagtaaatct caatataaat ttacatttgg ttctttgtgt
     8641 gttattttaa taataaatta agtgaaaatg ttattttaca ttaatatata atatctttgc
     8701 ataagagtga ataatataaa agagaaataa ttgataataa aaacttaaca aaaaaattaa
     8761 tacataaaaa aaaataaata taatgtgttg acatttaatt gaaatattca tacaataaaa
     8821 ttgaaaataa atatttccaa atgagattag cgagagagtc ctttatacga aaaggcgccg
     8881 aagaagaaat ttaagaaatg ccaattttta gagaagcttt caggcaaaaa tatcgctaat
     8941 tgatgggact ctggagagac ttaagttaag atactataag tcaccgaaga agcaaaataa
     9001 tattaaatta ttaaatcttt caggtataca aacagggata tataggctag gattattttc
     9061 catgctgata tatctttttt ttatgaaaaa gtacaggaaa taatatcaaa gttacttaaa
     9121 tacagtaggt ctaattttct agggagggtt atatatgaat gaattgaaaa gagtatcttt
     9181 gtacaatata cacaaagagc ttggagcaaa acttgttgaa tttgctggtt gggaaatgcc
     9241 tttagaatat gagggtataa ataaagagca tgagaaggtc agaaaaagtg caggtatatt
     9301 tgatgtatct catatgggag aggtacagat aaagggagca gagtcagaaa aatttataca
     9361 aaacctagtt acaaatgata taagcgcatt aaagataaat gatattatat atacacctat
     9421 gtgttatgaa aatggtggag tagttgatga tttattaata tataaatttg gtgaagaaga
     9481 ttatttatta gtaataaatg caggtaatat agataaagat gtagcatgga taataaaaca
     9541 aagtgaagga tacaatgtag atataaaaaa tatatctagt gaagtgagtc aattagcaat
     9601 tcaaggacct aaagcagaag aaattcttca aaaaatcaca gatatagact taaactcaat
     9661 aaaattttat aagtcaattc catcaacaaa agtatgtggt tgtccttgtt tagtttcaag
     9721 aacaggatat actggggaag atgggtttga gatatactgt aaaaataaat atgtagaaat
     9781 aatttggaat gaagttctaa aggttggagg agaagatata tgtccagctg gtctaggttg
     9841 tagggatact ttgagatttg aagcagctct acctctatat ggacatgaaa taaatgaaca
     9901 catatctcca attgaaggtg gtttatctat ctttgtgaaa acaaataaag aatcatttat
     9961 tggcaaatca attttatcaa aagaaaaaga aagtggagct aaaagaaagt tagtaggatt
    10021 tgaaatgcaa ggtaaaggaa tgcctagaaa tggatatgat ataaggattg gtgataaaac
    10081 agttggattt gtaacaacag gatgtgcatc tccaacgaca ggaaaaattt taggtatggg
    10141 aattatagat tctgaatatg caaaagtagg aaatgaaata ggtatagcaa tcagaaaaaa
    10201 agttgttcct gctgtgatag ttaagaaacc tttttataaa aaacaatata aaaaagataa
    10261 tattatatta aacaaagaaa ataaattttc atatatacct gctacaagtg aagataaatc
    10321 aaaaatgtta aaagtagttg gattaaattc ggttgatgaa ttattttcag atataccaga
    10381 agaagtaaaa ttaaaaagag atttaaattt ggaaattgga aaatctgaat tagaggtaag
    10441 caaaatagta aaaagattgt cagaagaaaa tttaagttta gaagacttga cttgttttct
    10501 tggtgctggt gcatatgacc attatatacc atcaattata aaacatataa cttcaagatc
    10561 tgaattttat acagcatata ctccatatca agctgaaata agtcagggaa ctttacaagt
    10621 agtttttgaa tttcaatcta tgattgcaga aattacaggt atggaaattg caaatgcatc
    10681 aatgtatgat ggagcaactg ctgcaataga agcatgtata atggcaatga atcagactag
    10741 aaaaagtaaa atagtagtgt caaaaactat tcatcctgaa actttgtcaa tattaagaac
    10801 ttacttacaa tataaagatt gtgagatagt agaaattgac ttttgtaatg aatatggcac
    10861 tacagatata gaaaaattaa aagcttctgt agacaaagat acagcatgtg ttcttataca
    10921 aactcctaat ttctttggaa ttattgaaga aatggaagaa atagaaaaga taactcatga
    10981 aaataaggct atgttaatta tgagtgtaga cccaatatca ttaggagttt taaaaacacc
    11041 aggtgagata ggtgcagata ttgttgttgg agaagctcaa tcacttggaa accctcttaa
    11101 ttttggaggt ccttatgtag gatttttagc tagcaaatct aaatatacta gaaaaatgcc
    11161 aggaagaata gttgggcaaa gtttagatgt agaaggtaaa attgcatatg tattaacttt
    11221 acaaactaga gaacagcatg taagaagaga aaaagcaact tctaatatat gttcaaatca
    11281 agctttaaat gctcttgtag cttcaatata tatagctact atgggtaaag aaggatttaa
    11341 agaggttggt atgcagtcta tgaaaaaagc acattatact tacaataagc ttgtacaaac
    11401 tggaaaatat aagccaatat ttaaaggtaa gtttttcaaa gaatttgctg tacaaggaaa
    11461 tcttaatata gaaactataa atgataaact cttagaagaa aatatattag gtggttataa
    11521 tttagaatac aattatccag aattaaaaaa ttcaactttg ctttgtgtga ctgagaaaag
    11581 aagcaaagag gaaatagata agttagttgg aataatggag ggattataat gaaagaatac
    11641 aatagtttgt tgatagatat atctaaaaaa ggtaggaaag catactcact tccaaagtta
    11701 gatatagatg atataaaaat agaaaatatg attgaccaag atatggcaag acaaagtgag
    11761 ttgaatttgc cagaagttgg tgaattagaa ttagttagac attatacatt attatcaaat
    11821 aaaaactttg gagttgatac aggtttttat cctttgggtt cttgtactat gaaatataat
    11881 cctaaaataa atgaagatat ggcagcactt ccaaacttta ctggaatgca tccataccaa
    11941 tcttcggata cagctcaagg ttctctttct ttgatgtatg atttatcaag aagacttgca
    12001 gaaattacag gtatggatga agttacacta caaccttcag caggttctca tggtgagttt
    12061 acagggctta tgattataaa agcatatcat gaaaatagag gtgaccataa gagaaccaaa
    12121 gtgataattc cagattctgc acatggaaca aatccagcaa gtgcagctat ggcaaacttt
    12181 gatgtgattc aaatagcatc tgataaaaat ggagctgtag acataaatgc attaaaagag
    12241 gttttgaatg atgaagtagc agctcttatg cttactaatc caagtactct tggtttattt
    12301 gaaaaaaata taaaagaaat agctactctt gtacatgaag caggaggact tttgtactat
    12361 gatggtgcaa acatgaacgc tattatgggg ataacaagac ctggagatat ggggtttgat
    12421 gtggttcatc ttaatcttca taagactttt tcaactcctc atggaggtgg aggtccagga
    12481 gctggtcctg ttggagttaa aaaagaatta gtaccttttt taccaatacc agtaattgaa
    12541 agaaaagaag ataagtatgt actaaattat gatagagaaa aatctattgg gaaaattaaa
    12601 aatttctatg gtaattttgg agttcttgta agagcttaca catatatact aactatggga
    12661 agggatggac ttaaagaggc tagtgaaatg gcagttttaa atgctaatta tataaaggaa
    12721 agtataaaag atgattatat tttgccaata gataccttgt gtaagcatga gtttgtatta
    12781 ggtggattgc caagaggaga ggccaatata aaaactatcg atattgcaaa aagactacta
    12841 gattatggat accatcctcc aacaatgtac tttcctctta ttataaatga ggcacttatg
    12901 atagaaccta cagaaagtga gagtatagag acattagata gttttataga agctatgaaa
    12961 agtgttgcta aagaggcaaa ggaagaacca gaactattga aaactgctcc acataatact
    13021 ttggtcaaaa gagtagatga tgcaagggca gtaaagaaac ctatactaac atggtcacaa
    13081 agataaatag ttaaaaagta gagatttaaa gtataaagag aattaaattt gtaagaaaaa
    13141 gctatctaac ttaatctagt ttagatagct tttttgtata ttagtatgta tggtattttc
    13201 tatataaagt tttaaattat attagtgctt atatagaata ttgatatgat gattatgtat
    13261 agatattaat aagaattgtt gaatttatct tgcctta
//
LOCUS       DAMJVG010000098        12761 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.101, whole genome shotgun sequence.
ACCESSION   DAMJVG010000098 DAMJVG010000000
VERSION     DAMJVG010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12761)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12761)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12761
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.101"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            120..1610
                     /locus_tag="PC512_003206"
     CDS             120..1610
                     /locus_tag="PC512_003206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HDF2442933.1"
                     /translation="MFQFETQIHKLRHDVLTAIARLGKEDNLTREAMDNIQYEIIKGE
                     KPTYRCCVYKERAIISERVNVSMGLQPGQDKIDLDTMDIEEDEQIIYILEAACDSCPI
                     NEFTVTDICRGCLAHRCKEACKFGAITHVGGMAYINHELCKACGMCKKACQYDAISEV
                     VRPCKSVCPTNALGFDRENMKAMIHEDKCLNCGACMSACPFGAISDKSLIAPVARKLV
                     QKEKMYAVVAPAITGQVEANVTYGQIKNAIKSLGFVDVLEAACGADAVTVHESLEFAE
                     RMEKGEAFMTNSCCPGFVGYIEKTYPNHVGKISSTVSPMIASGRFIKSHEPDAKVVFI
                     GPCTAKKSEAAKKELKGAVDYVLTFEEIMALFEAFDIDLAKCSNEDIDDASIFGRGFG
                     AAGGLTKAIENYLAEKGIGVNFEPVKISGSREIKKTMTMANLGKLEGNFIEGMMCEGG
                     CINGSGKFLSGAKVKATFDRKNSQSTKKSVLANTKIKDFSNINLEK"
     gene            1890..3386
                     /locus_tag="PC512_003207"
     CDS             1890..3386
                     /locus_tag="PC512_003207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HDF2442934.1"
                     /translation="MFEFETQLKRLKHEVLTAVARLSIEENLTKENIEKIPYEIIKGE
                     KARYRCCVYKEREVVLERAQLALSLTPNSKYGDINPDSVSLDTDEQIIYIVEAACDRC
                     PINEFTVTELCRGCLAHRCKEACKFGAISYINGRAYINHDLCKACGMCKSSCQYDAIS
                     EVVRPCKSVCPTGALDFNRNTMKAMIHEDNCINCGACMSACPFGAISDKSLIAPVAKK
                     LAKKENMYAIVAPAITGQIDSNITYGQLKNAIKSLGFVDMIEASCGADAVTVHESNEL
                     IERIKSGDNYMTNSCCPGFFKYIEKMFPDEKDRISSTVSPMVATGRLVKKIDSDAKVV
                     FIGPCTAKKSEATEKSLKDSVDYVLTFEELMALFEAFNIDLSKCSNEDINDGSIFGRG
                     FGASGGLAKSVQNYIAEKGLSFDFEPIKVSGPRQIKKTMTMAKLGRLEGNFIEGMMCE
                     EGCINGAGKFLSGVKAKNTFDRKNGQSTKKSVLSNDKIKEFEDVNLER"
     gene            3520..4434
                     /locus_tag="PC512_003208"
     CDS             3520..4434
                     /locus_tag="PC512_003208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2442935.1"
                     /translation="MRKIVLKDILFLVTTLSIIVILLLVTNITTNSKIKSTNESYLKS
                     DKNDVSQNNIQSSTKNTAFKTTILSTGKSDCILVEIGNKVIMIDTGEDKNGKQIVDRL
                     KEKGINTLDYLILTHLDKDHIGGVDSVLSSVKVKNIIQANYKKDSKQYDEYIDSLKKA
                     DIEPVLLKDNMNIVINSAEINIHPASKSKYESSNDYSIITNISYGAHKFLFAGDAEEE
                     RLSEFINGNTLKYDFVKMPHHGRYDKLTETFLESISPQYAVITCSEKKEPEEGVLKIL
                     ERLNIKTFLTSNGEVVINSDGKTLSVNQ"
     gene            4552..4743
                     /locus_tag="PC512_003209"
     CDS             4552..4743
                     /locus_tag="PC512_003209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442936.1"
                     /translation="MLDRFFGEGGFGGCAWWIIILFFLFLAFQDCWAEMDLCAWIPFL
                     ILLLILCECGDVFDGGCGC"
     gene            4966..5316
                     /locus_tag="PC512_003210"
     CDS             4966..5316
                     /locus_tag="PC512_003210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442937.1"
                     /translation="MAIVDKIFNEIKLMVARLLLGKKYSEYEEKDLVYNTEEEVILIT
                     LKRLVFQGNVNEAEEILFDKAKSVNSENMQYIAIEFYTMLMEKTDEELEAMNFSKQEV
                     YQGIEDIRKVLNLE"
     gene            5578..7083
                     /locus_tag="PC512_003211"
     CDS             5578..7083
                     /locus_tag="PC512_003211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003374392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HDF2442938.1"
                     /translation="MKVGFDHKKYLEEQSKYILERVNNFDKLYLEFGGKLMGDLHAKR
                     VLPGFDENAKIKVLQHMKEKVEVVICVYAGDIERNKIRGDFGITYDMEVLRLIDDLRG
                     YELDVNSVVITRFEGQPATTVFINKLERRGIKVYKHYPTKGYPSDVETIVSDEGYGAN
                     EYIETTKPIVVVTAPGPNSGKLGTCLSQLYHENKRGNVVGYSKFETFPVWNVPVKHPL
                     NIAYEAATVDLKDVNMIDSFHLETYGEMSVNYNRDLELFPVLKKIIEKITGKESIFQS
                     PTDMGVNRVGFGIIDDEVIRKASIEEIIRRYFKTACEYKKGQVDKGAYDRMKMIMEEL
                     NLKPEDRNVVLPARNYSNKLKESADKNDTCPVVALELEDGTILTGKGSDLMNGTAAVV
                     LNAIKHLANISDDMHLISPVILEPIINLKTKTLASRNVSLSCQEVLTALSICAVTNPT
                     AQFAMEKLALLKGCQAHSTTILNRDDEQTFRKLGIDVTCDPEYPSQNLYYS"
     gene            7473..8570
                     /gene="dinB"
                     /locus_tag="PC512_003212"
     CDS             7473..8570
                     /gene="dinB"
                     /locus_tag="PC512_003212"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HDF2442939.1"
                     /translation="MKHYRKIIHIDMDAFYASIEQRDNKKLKGRPVIVGGNPQSRGVV
                     ATCSYEARKFGIHSAMPSAVAYNRCPYAVFVRPRFDVYKSVSEQIRDIFYRYTDLVEP
                     LSLDEAYLDVTKNKKNIDSSIEIAKQIKKDIFREVGLTSSAGVSYNKFLAKIASDLRK
                     PNGLTVITEENAQDFLDKLPVNKFFGVGKVTSNTLKNLGIKTGYDLRCLNLFELENIF
                     KKRGYELYKFARGIDDRPVEPNRVRKSVGAETTLSHNLDIDEEETRNILDELCEEVCH
                     RLKNSEKFGKTLTLKIKYEDFTKITRSLSLEHYIDEYNDIRSGVDNLLRNVDVNGKQI
                     RLLGVTISNLSDKKETYKDITLFEYMDSIQM"
     gene            8833..9969
                     /locus_tag="PC512_003213"
     CDS             8833..9969
                     /locus_tag="PC512_003213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2442940.1"
                     /translation="MIEIRNVTKKIGNNVILDDISLVVETGTLVVLIGSSGCGKTTTL
                     KLINKLIKPTSGEIYINGKPISQENEIELRRKIGYVIQNTGLFPHLTIKENIELIPRL
                     KKEKSVEEIEKRTLQLLEMVGLDSDEFLNKYPSELSGGQQQRIGVARAIATDAEIILM
                     DEPFSALDPITRTSLQEQLFSLQDELKKTIIFVTHDMDEALKIADKICIMKDGRIAQY
                     DTPENILRKPANDFVKDFIGEDRVWDNPEYIKARDIMIKNPIAVNSTRTVTQGIEIMR
                     TSKVDSLLIIDRAKTLKGIVTVKDMKDIDDKSILLADIMSSEPLHVNEGDNLVEILNV
                     MNRNSVGYIPVISDENKLVGLITRSSLLSVLSEQFLEMEVSVLG"
     gene            9962..11509
                     /locus_tag="PC512_003214"
     CDS             9962..11509
                     /locus_tag="PC512_003214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HDF2442941.1"
                     /translation="MANFFNFILLQKDKIIELLIQHMSLTVTSILIAIIVGVPLGIII
                     SRISSLRKFVLGFVNLVQAVPSMALLGLLVPILGIGSKPAIFMVVVYSLLPIVKNTYI
                     GITSIDPVVLESAKGIGLTRNQTLFKIQFPLALPIIMGGVRISAVTAVGLMTLAAFIG
                     AGGLGYLVFSGVQTVNNNMILAGAIPSCIIALLVDYLFSKIEVAVTPKGLNPKAPKKN
                     YIALKVISVVLVVSMLFVVFSSSFSSKKDTITIGSKDYTEQLILGNVYAELVEKNTNL
                     KVKKNLNLGGSSVAFNAIKSGELDMYVDYTGTLLVNVMKHAPIKDADEAYNVVKDTME
                     KENQLTLLDPLGFNNTYTLAMMPETAEKYGINTISDLTKYGKEFTFSPTLEFENREDG
                     LVGLSRDYGLKFKDVKAMNGSLRYTALDNNESQVIDAFLTDGLIKKFNLKILEDDKNF
                     FVPYYAAPLVREDTLKKYPELEKVMNMLSGKINEETMRELNYQVDELGKSPEEVAHSF
                     LVKEGLV"
     gene            11843..12709
                     /locus_tag="PC512_003215"
     CDS             11843..12709
                     /locus_tag="PC512_003215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HDF2442942.1"
                     /translation="MDNYKKVKQVLWIILFANFAVALLKIIIGNQIKSYSMTADGFHS
                     LSDGASNIVGLIGIFFASKPKDKNHPYGHKKFEIITSLFISGMLFVIAIKIILSAVLR
                     IANPVVPAITIESLIALIITLFINIFVCMYEYRIGTKLNSYVLISDSLHTRSDIFVSL
                     GVLVTLVGVKLGFPVIIESIVPIIISAFIIYSAYGIFRPSIGILVDRVAVDEDYIKEI
                     VFEFNEVRDVHNIRSRGSKSSIYIDMHVMVDPFISVEQSHDLTHKIEKQIQEEINENA
                     QVIVHIEPFYSF"
BASE COUNT         4946 a         1334 c         2325 g         4156 t
ORIGIN      
        1 cactatatat attcgataaa ataaaattta aacatataat attttatgta tatattaata
       61 aaaggacata ttgtgttata atggtatcgt ataaaatcat ttacgggggt ggtattaaaa
      121 tgtttcaatt tgaaacacaa atacacaaat taagacatga tgttttaact gcaatagcta
      181 gacttggaaa agaagataac cttaccagag aagcaatgga taatattcag tatgaaataa
      241 taaaaggtga gaaacctaca tacagatgct gtgtttataa agaaagagct ataatatctg
      301 agagagtaaa tgtaagtatg gggttacaac caggtcaaga taagatagat ttagatacaa
      361 tggatataga agaagatgaa caaattatat atattttgga agctgcatgt gacagttgtc
      421 caataaatga atttacagta acagatattt gtagaggatg tctagcacat agatgtaaag
      481 aagcttgtaa atttggagct ataacacatg tcggaggaat ggcctatata aatcatgaat
      541 tatgtaaggc ttgtggaatg tgtaaaaaag cttgtcaata tgatgccatc tcagaggttg
      601 ttagaccatg taagagtgtt tgtccaacta atgccttagg atttgataga gaaaatatga
      661 aagctatgat acatgaggat aaatgtttaa actgtggagc atgtatgtca gcatgtccat
      721 ttggagcaat atctgataag agtttgatag ctcctgtagc tagaaagtta gttcaaaaag
      781 agaaaatgta tgcggtggta gctccagcta taacaggtca agttgaagca aatgttacat
      841 atggtcaaat aaaaaatgct ataaaatcac taggatttgt tgatgtatta gaagcagctt
      901 gtggagcaga tgcagttaca gttcatgaaa gcttagaatt tgctgaaaga atggaaaagg
      961 gagaagcttt tatgacaaat tcttgttgtc caggatttgt tggttatata gaaaaaacat
     1021 acccaaatca tgtaggaaaa atatcttcta cagtgtctcc tatgatagct agtggtagat
     1081 ttataaaaag tcatgaacca gatgctaaag ttgtattcat aggaccatgt acagccaaaa
     1141 agagtgaggc agctaagaaa gaattaaaag gagctgttga ttatgtactt acttttgaag
     1201 aaataatggc attatttgag gcatttgata tagacttggc taagtgttca aatgaagata
     1261 tagatgatgc atcaattttt ggaagaggtt ttggagctgc tggtggtctt acaaaagcta
     1321 tagaaaatta tcttgctgaa aaaggtattg gtgttaattt tgaacctgta aagatttctg
     1381 gttcaagaga aatcaagaaa actatgacta tggctaattt aggaaagcta gaaggtaatt
     1441 ttatagaagg aatgatgtgt gaaggtggtt gtataaatgg ttctggtaaa ttcttatcag
     1501 gtgcaaaggt taaagccact tttgatagaa aaaattctca atcaactaag aaaagtgtct
     1561 tagcaaatac aaagataaaa gattttagta atataaattt agaaaaataa agataataca
     1621 aagcaacaaa aatacatatt gttaatagag ttgttctaag ttgaggttta acttttggac
     1681 aactctattt ttatttatat atttaattat tgaacaacta aaataaaaat tatatacact
     1741 taaaataaaa attacatata taatattttg tatataactt aacaaagtat atgcctatgt
     1801 tataataatt tatagaaata aataaaaaat acaatataca taatagtaga aatatagcaa
     1861 aaaggtgtga tttataggga ggattactta tgtttgaatt tgaaacgcaa ctaaaaaggt
     1921 taaaacatga agttttaaca gcagtagcaa gactatctat tgaagaaaat ttaacaaaag
     1981 aaaatataga aaaaattcca tatgaaataa ttaaaggaga aaaggcgaga tatagatgtt
     2041 gtgtttataa agagagagaa gtagttcttg aaagggcgca acttgcatta agtttaactc
     2101 caaatagtaa atatggagat ataaatccag attcagttag tttggacaca gatgagcaaa
     2161 ttatatatat agttgaagca gcatgtgata gatgtccaat aaatgaattt acagttacag
     2221 agctttgtag agggtgtttg gctcatagat gtaaggaagc atgtaaattt ggggcaattt
     2281 cttatataaa tgggagagca tatataaatc atgatttatg taaggcttgt ggaatgtgca
     2341 aaagttcatg tcaatatgat gctatatcag aagttgtaag accttgtaaa agcgtttgtc
     2401 caacaggagc tttggatttt aatagaaaca ctatgaaagc aatgatacat gaagataatt
     2461 gtataaattg tggagcatgt atgtcagcat gtccatttgg agcaatatct gataagagtt
     2521 tgatagcacc tgttgcaaaa aaacttgcaa agaaagaaaa tatgtatgca atagtagctc
     2581 cagctataac aggtcaaata gatagtaata ttacatatgg tcagttaaaa aatgctataa
     2641 aatcactggg atttgtagat atgatagaag cttcttgtgg agcagatgca gttacagttc
     2701 atgaaagcaa tgaacttatt gaaagaataa aatcaggaga taattacatg acaaattcat
     2761 gttgtccggg attttttaag tatatagaga agatgttccc agatgaaaaa gatagaatat
     2821 catctacagt gtctcctatg gtagcaacag gaagattagt aaaaaaaata gattctgatg
     2881 ctaaagttgt atttataggt ccatgtacag ctaaaaagag tgaggcaaca gagaaaagtt
     2941 taaaagattc agtagattat gtacttactt ttgaagaact aatggcatta tttgaagcat
     3001 ttaatataga tttatcaaaa tgttcaaatg aagatataaa tgatggttcg atttttggaa
     3061 ggggatttgg agcatctggt ggacttgcca aatcagtaca gaactatatt gctgaaaagg
     3121 ggcttagttt tgattttgaa cctataaaag tatctggtcc aagacaaatt aaaaagacaa
     3181 tgacaatggc taaattggga agattagaag gtaattttat agaaggaatg atgtgtgaag
     3241 aaggttgtat taatggagca ggtaagtttt tatcaggtgt aaaagctaaa aatacttttg
     3301 atagaaaaaa tggacaatct actaaaaaga gtgttttatc taatgataag attaaagaat
     3361 ttgaagatgt aaatttagaa agataattgt tttggtacag tcattttttt atcatgccac
     3421 aaatatgcct aaaatttgcc ctttttatat gtgtatttta cagagttaag gttgctatac
     3481 tataaatatg taataaataa aatttatagg agcttttgga tgaggaaaat agtattaaaa
     3541 gatatcctgt ttttagttac tacattatct ataatagtaa tattattgct tgtaacaaat
     3601 ataactacta atagtaagat aaaatcaacg aatgaatctt atttaaaaag tgacaaaaat
     3661 gatgtgagtc aaaataatat tcagagtagc acaaaaaata ctgcatttaa gactactata
     3721 ttaagtactg gaaagtctga ctgtatattg gttgaaatag gtaacaaagt cataatgatt
     3781 gatacaggag aagataaaaa tggaaaacaa atagtggata ggttaaaaga aaaaggaata
     3841 aatacacttg actatttaat tttaactcat ttagataagg accatatagg tggagtagat
     3901 agtgtgttat ctagtgttaa agtaaagaat attatacaag caaattataa gaaagatagt
     3961 aagcaatatg atgaatatat tgattcactt aaaaaagctg atatagaacc agtgctacta
     4021 aaagataata tgaatattgt aatcaatagt gcagaaataa acatacatcc ggcttcaaaa
     4081 agcaagtacg agagttcaaa tgattattca ataatcacta atataagcta tggagcacat
     4141 aagtttttat ttgcaggaga tgcagaggaa gaaagattgt cagagtttat aaatggaaat
     4201 actttaaaat atgattttgt taaaatgcct catcatggaa gatatgacaa attaactgaa
     4261 acatttttag agtctatttc accccaatat gctgttatta catgttcaga gaaaaaagaa
     4321 ccagaggaag gtgttttaaa aatattggaa agattgaata taaaaacatt tttgacttct
     4381 aatggagagg tagttatcaa tagtgatggt aagacattga gtgtgaatca ataatttttt
     4441 taaaaatatc taaaaaaatt taaaaaaatc attagcaaat attacccctt aaacatagta
     4501 tattttagga gctgaaactc cacatacaaa atgactagga ggtaacatat tatgttggat
     4561 agattttttg gtgaaggcgg atttggtgga tgtgcttggt ggataataat attattcttc
     4621 ttattcttag cattccaaga ttgttgggct gaaatggact tatgtgcatg gatacctttc
     4681 ttaatattat tattaatact ttgtgaatgt ggtgacgttt ttgatggagg atgtggatgc
     4741 taaaaaaatc aatttagatg atttaataaa gcttatggtg ggtataaata aaataccaaa
     4801 ccaatcacaa tctagtgttt gaaggtagtc ggaaatcccc cgctaccttc ttttttttat
     4861 tgttaaaatt tatttttgaa ttatttcatt tacatataat aatttttacg ataaagtctg
     4921 atataattaa aaagaaaata aaatttattt ataggagatg taaaaatggc tatagtggat
     4981 aagattttca atgagataaa acttatggtt gcaagacttt tattgggaaa aaaatacagt
     5041 gaatatgaag aaaaagattt agtgtataat acagaagaag aagttatact tataacttta
     5101 aaaagattag tttttcaggg aaatgtaaac gaagcagaag aaattttatt tgataaagct
     5161 aagagtgtaa atagtgaaaa tatgcagtat atagcaatag aattttatac tatgcttatg
     5221 gaaaaaactg atgaagaatt agaagctatg aatttttcta aacaagaagt ttatcaaggt
     5281 atagaagata ttagaaaagt attgaattta gaataaaaga tatatgaaaa tattgaaata
     5341 aattaatgct aaggtgagaa tattatactt atatataaaa atatagtatt cttattttat
     5401 tagttatatt aggtatatct tatttaccat aaaactatct tgaaaaaaat taatcttaat
     5461 tgtataatat tactttgagt gaaaaagtat taacattttt ttataagatg ttttactaaa
     5521 aaaatatata taaatatact gttatcaata agaaatttaa tttagtgagg tgttaagatg
     5581 aaagtaggat ttgaccacaa aaaatattta gaagagcagt ctaaatatat cttagaaaga
     5641 gtaaataatt ttgacaaact ttatttagag tttggaggaa aattgatggg agaccttcat
     5701 gcaaaaagag tacttccagg atttgatgaa aatgcaaaga taaaagtatt acaacatatg
     5761 aaagaaaaag ttgaagttgt aatttgtgtc tatgcaggag atatagaaag aaacaaaata
     5821 agaggagact ttggtatcac ttatgatatg gaagttttaa gattaataga tgatttaaga
     5881 ggttatgaac tagatgtaaa tagtgtagta attactagat ttgaaggaca acctgctaca
     5941 actgtattta taaataaatt agaacgtaga ggaattaaag tttataagca ttatccaaca
     6001 aagggatatc cgtcagatgt tgagactata gttagtgatg agggatatgg agcaaatgaa
     6061 tatatagaaa ctacaaagcc aatagtagta gtcacagcac caggacctaa tagtggaaaa
     6121 cttggtactt gtctaagtca gttgtatcat gaaaataaaa gaggtaatgt agttggatat
     6181 tctaagtttg agacattccc agtttggaat gtacctgtaa aacatccttt gaatatagct
     6241 tatgaagcag ctacagttga tttaaaagat gtgaatatga tagattcatt ccaccttgaa
     6301 acgtatggtg aaatgtcagt aaactacaat agagatttgg aattatttcc agtgcttaaa
     6361 aaaataatag aaaagataac tggaaaagaa tcaattttcc aatctccaac tgatatgggt
     6421 gttaatagag ttggctttgg aataatagat gatgaagtaa taagaaaagc ttctatagaa
     6481 gaaataataa gaagatactt taaaactgcc tgtgagtata aaaagggaca agttgataaa
     6541 ggtgcttatg atagaatgaa aatgattatg gaagagctta acttaaagcc agaagataga
     6601 aatgttgtat tacctgctag aaactacagt aataaattga aagaaagtgc tgacaagaat
     6661 gatacttgtc ctgtagttgc attagaatta gaagatggta caatattaac tggtaagggt
     6721 tctgatttaa tgaatggaac tgcagcagta gtattaaatg ccattaaaca tttagccaat
     6781 atatctgatg atatgcactt aatatcacct gtaatattag aacctatcat aaacttaaaa
     6841 acaaagactt tagctagtag aaatgtttca cttagttgcc aagaggtgtt aactgcactt
     6901 agtatttgtg ctgtaactaa tccaactgca caatttgcta tggaaaagtt agcattatta
     6961 aaagggtgtc aagctcattc tactactata ttaaatagag atgatgaaca aacatttaga
     7021 aagcttggta tagatgtaac ttgtgaccca gaatatcctt cacaaaatct ttactatagt
     7081 taaaattata taaaaaaata tgggctgttt taaagtaata gtttgagcag tccattacaa
     7141 ttataataaa atcagtaggc tgtcttgcat aagacagtct tttgttttta aaacatccca
     7201 taaattaaat atatatactg ttatccataa ggaattttaa atttagttcc ttggaatacc
     7261 tattgtaaag cttttatata gtttttgcaa gtgtttttaa ggatttttta taaattatat
     7321 tgaagttaat ggattataga tggttttatt tatggaaaat atgaatatat aaagaaaata
     7381 atgaaaaaat accaaaaaga aacataagtt tggtataatt aaaaagtaat ataaataaaa
     7441 ttaatctatt tatactttaa aaggtgataa taatgaaaca ttatagaaaa ataattcata
     7501 tagatatgga cgctttttat gcatctatag aacaaagaga taataaaaaa ttaaaaggaa
     7561 gacctgttat tgtcggtgga aatccacaaa gccgaggtgt ggttgcaacg tgttcttatg
     7621 aagctagaaa atttggtatc cattcagcta tgccatcagc tgtagcttac aataggtgtc
     7681 catatgcagt ttttgtaaga cctcgatttg atgtttataa gagtgtgtca gagcaaataa
     7741 gagatatatt ttatagatac acggatttag ttgaaccatt atctttagat gaagcttact
     7801 tagatgtaac aaaaaataaa aaaaatattg attcatcaat tgagatagca aagcaaataa
     7861 aaaaagatat atttagagaa gttggtctta cttcttcagc tggtgtgtca tacaataagt
     7921 ttcttgctaa gattgcatca gacttaagaa agccaaatgg gttaactgta ataaccgaag
     7981 aaaatgccca ggacttttta gataaattac ctgtgaataa attttttggt gttggaaaag
     8041 ttacttcaaa tactcttaaa aatttaggta taaaaactgg atatgattta aggtgtttaa
     8101 atttatttga acttgaaaat atattcaaaa aaagaggtta tgaattatat aaatttgcta
     8161 gaggaataga cgatagacca gtggaaccaa atagggttag aaaatctgtt ggggctgaga
     8221 ctacattaag tcataatttg gatattgatg aagaagaaac acgcaacatt cttgatgaac
     8281 tttgtgaaga agtatgtcat agattaaaaa actctgagaa gtttggaaaa acattaacat
     8341 taaaaattaa atatgaggac tttacaaaga taactagaag ccttagttta gaacactata
     8401 ttgacgaata taatgatata agaagtggtg tagataattt gttgagaaat gttgatgtta
     8461 atggaaaaca aattaggcta ttgggagtta caatatcaaa cctaagtgat aaaaaagaaa
     8521 cttataaaga tattacatta tttgaataca tggatagtat ccaaatgtga gttttgttta
     8581 aatgaaataa cactagcttt aatactatat aattgaggct agtgttattt tatgaatatt
     8641 tttatatttt ttgttttttg acattatgta ttatatacta tatataaata ctttatattt
     8701 gtagcaatat tcagacaaat agtgacctaa aaatcgtact ttgtttacat aaataaaata
     8761 gtatgatata attataaaaa caacttataa tattgaagaa ggttgcttgt tcgaaaaagg
     8821 ggatgataaa ttatgataga gataagaaat gtaacaaaaa aaataggaaa taatgttata
     8881 ttagatgata tttctctagt tgtagaaaca ggtacattgg tagttttgat tggttcaagt
     8941 ggttgtggaa agactactac tttgaagctt ataaacaaat taataaaacc tacatctggt
     9001 gagatatata ttaatggcaa accaatttct caggaaaatg aaatagagct tagaagaaaa
     9061 ataggatatg ttatacagaa cacaggccta ttccctcatc ttacaataaa agaaaatata
     9121 gagctaattc cacgcctaaa aaaggaaaaa tccgttgaag aaattgaaaa aagaacgttg
     9181 caactacttg agatggtagg acttgatagt gatgaatttt tgaataagta tccttcagaa
     9241 cttagtggtg gacagcaaca aagaatcggt gttgcaagag ccattgctac tgatgctgaa
     9301 ataatattga tggatgagcc ttttagtgct ttagacccaa taacgagaac atctttacaa
     9361 gaacaattat tttctcttca agatgaattg aaaaaaacta taatatttgt aactcatgat
     9421 atggatgagg ctttaaagat agctgataaa atttgtatta tgaaggatgg aagaatagca
     9481 caatatgata ctcccgaaaa tatacttaga aagcctgcaa atgactttgt aaaagatttt
     9541 atcggagaag atagagtttg ggataatcca gaatatataa aagcaagaga tattatgata
     9601 aaaaatccta ttgctgttaa ttctactaga actgtaactc aaggaataga aattatgaga
     9661 acgagtaagg ttgatagctt actaattata gatagagcaa aaacattaaa aggtattgtt
     9721 actgtaaaag atatgaaaga tattgatgat aagtcaatat tacttgctga tattatgtca
     9781 agtgagcctt tgcatgtaaa tgaaggtgat aatttagtag aaatactaaa tgtaatgaat
     9841 cgtaattcgg ttggatatat tccggttatt tctgatgaaa ataaactggt agggcttatt
     9901 actagaagta gtttactttc tgttttaagt gaacaattct tagaaatgga ggtgagtgtt
     9961 cttggctaat ttttttaact ttatactatt acaaaaagat aagattatag agcttttaat
    10021 acaacatatg agtctaactg ttacatctat tttaatagct ataatagttg gtgttcctct
    10081 tggaataatt atttcaagaa tctcatctct tagaaagttt gtacttggat ttgtaaactt
    10141 agtccaagca gttccgtcta tggcactttt gggtcttctt gtacctatac ttggtatagg
    10201 aagtaaacca gccatattta tggtagtggt ttattcatta ctaccaattg taaaaaatac
    10261 gtatataggt ataacaagta ttgacccagt agtattagaa tcagctaaag gtattggtct
    10321 tacaagaaat cagacattat ttaaaataca atttccttta gcgcttccta taataatggg
    10381 tggagttaga atatctgcag ttacagctgt tggtttgatg actcttgcag catttatagg
    10441 tgctggtggt ttgggatatt tagtattttc aggggttcaa actgtaaata ataatatgat
    10501 tttagcaggg gcaatcccat catgtataat tgcactgtta gttgattatt tatttagtaa
    10561 aattgaagtt gcagttactc caaaaggatt aaatccaaaa gcacctaaga agaattatat
    10621 agcacttaaa gtaatatctg tagtgcttgt tgtttcaatg ttgttcgttg tttttagttc
    10681 tagtttttca agtaaaaaag atacaataac tattggttct aaagattata cagaacaact
    10741 tatacttggc aatgtttatg ctgaattagt agaaaaaaat acgaatctta aagttaagaa
    10801 gaatttaaat ctaggtggtt catctgttgc gtttaatgca attaaatctg gtgagttaga
    10861 catgtatgtt gactatacag gtacactttt ggtaaatgta atgaaacatg ctccgattaa
    10921 agatgctgat gaagcatata atgttgtaaa agatactatg gaaaaagaaa atcagttaac
    10981 tttacttgac cctcttggat ttaataatac ttacacatta gctatgatgc ctgaaactgc
    11041 tgaaaagtat ggaataaata ctatttctga tttgactaaa tatggtaaag aatttacatt
    11101 ctcaccaact ttggagtttg aaaatagaga agatggtctt gtagggcttt ctagagatta
    11161 tggtttaaaa ttcaaagatg taaaagcaat gaatggaagt ttaagatata cagctttaga
    11221 taataatgaa tctcaggtta tagatgcatt tttaactgat ggtcttatta aaaagtttaa
    11281 tcttaagata ttagaggacg ataaaaattt ctttgtacca tattatgcag caccattagt
    11341 aagagaagat actttgaaga aatatcctga gttagaaaaa gttatgaata tgctttcagg
    11401 aaaaataaat gaagaaacta tgagagaact taactatcaa gtggatgaac ttggtaaatc
    11461 accagaagaa gttgctcatt cattcttagt taaagaaggc ttagtataaa aaattaatag
    11521 tttatatcaa aaatttaagg gagtgtctca aaatgaactt tttagttcat gaggcactct
    11581 tttttatatg aaatcaaata tattttatca tttcaacaat aaaaaagaag attatcttta
    11641 ttttgagaca gtctcttatt tttatgtata ccaaaaccat acctacgatt tttatttata
    11701 attaagtttc aaatagaatg aacaagtaca accaattttg aatataaata tagtaaatgt
    11761 gcttatatac gattttattg tctggttgat tgatattgat agatagcttt ctttattgaa
    11821 tcgaagggag ggggaatttg ttatggataa ctataagaaa gtgaagcaag tattgtggat
    11881 aattttattt gctaattttg cagtagcatt attaaaaatc attattggta atcaaataaa
    11941 aagctatagt atgacagcag acggatttca ttctttgtca gatggagcat ctaatatagt
    12001 ggggcttata ggtattttct ttgcatctaa accaaaagat aaaaatcatc cttatggaca
    12061 taaaaagttt gaaattataa ccagtttatt tataagtggt atgttgtttg ttatagcaat
    12121 taagataatt cttagtgcag tgttaagaat agctaatcca gttgtacctg ctataactat
    12181 agaaagttta attgctttaa ttattacact ttttataaat atttttgtat gcatgtatga
    12241 atatagaatt gggactaaac taaatagtta tgttttgatt tcggattcat tgcatacaag
    12301 aagtgatata tttgtgtctc taggtgtatt ggttacttta gttggtgtta agttaggatt
    12361 tccagtaata atagaatcta tagttcctat tattatttct gcattcataa tttattcggc
    12421 ttatggaata tttaggccat ctattggaat tttggtcgat agagtggctg tagatgagga
    12481 ttatataaaa gaaattgtgt ttgaatttaa tgaggtaagg gatgttcaca atatcagaag
    12541 tagaggtagc aaaagttcta tttatattga catgcatgta atggtagacc catttataag
    12601 cgtagagcaa tctcatgatt taacacataa aattgagaaa caaatacaag aagaaattaa
    12661 tgaaaatgct caagtaatag tccatattga acctttttat agtttttaac ttagttataa
    12721 aatacaagtt ataaaaaaat ataatttata aaaaaaatat t
//
LOCUS       DAMJVG010000099        12726 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.103, whole genome shotgun sequence.
ACCESSION   DAMJVG010000099 DAMJVG010000000
VERSION     DAMJVG010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12726)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12726)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12726
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.103"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(222..2102)
                     /locus_tag="PC512_003216"
     CDS             complement(222..2102)
                     /locus_tag="PC512_003216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp10"
                     /protein_id="HDF2442943.1"
                     /translation="MSKRKSFIRTIAVSTMAVAVTGSATCAYAAPVLQGTKTYEKVNT
                     IDISVDSVENIVYSFQASIKVQGEVEVVDNEQKEKITWSDNIKSQIKSGNANATCRVE
                     YNKSSNTTTLDIYVTSNEDLLDGNRLNIGRISVKKSGSNSNADYKVLGKGTNDKPALK
                     IVTYNNKTVDYENISSDEGLIFTLINESEVKPIGGTGSSKNDPEKYKVEKSEALEYLL
                     NNIRINYSIVSKETQESGSNVILKLGLAQKTTKGRKATINKYVEVTLPKSLEYIVENE
                     LSKPDELPPDNGNGGNNGGGSNSGGSSSGGSSGGGSSSDSTSNVTVKKLKGADRFETA
                     IKISQSGWTKSDTVVIVNGEDKSMVDGLTATPLASVKNSPILLSSNEKLPQKTVEELK
                     RLNPSKVIVIGGNNSMPNSVVEAIKAVNSKISVQRIGGDTRYQTSINIAKEIDKTNNV
                     SKLYIGAGNGEADSLSIASLAGKEKTPIVLTQKDGVDNEAEQFIKSNKVSNIYFIGGV
                     EKISNKAIEQVGKIANKDISNNRVAGQTRQETNAKVIDKFYSQSKLDGVVVANQDKLI
                     DALAVGPLAAKNNSPVILATNTLDKSQESSLKGKNSSKLFEVGGGIASSVIDKIKSLI
                     EK"
     gene            complement(2306..8269)
                     /locus_tag="PC512_003217"
     CDS             complement(2306..8269)
                     /locus_tag="PC512_003217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-binding adhesion protein"
                     /protein_id="HDF2442944.1"
                     /translation="MKKAISCVLAVSMCSAPLNVFAEPILEGKLRAVEKSVTEKLRGS
                     LEVDLNFSLPIKNSESESMTNMQLRLKDDSNNSGIIKLGEKDSGTVNVGTDNIEYTIK
                     KLSASRSEIKNKDENISYYNIVFNNLPVGKYNVEVSGDGFKNKEIKDIDISSYSQRVL
                     LSNRASVDNKNKPLNYELFLMGDVNGDGKVDKSDYNKVLENIDSNKREFDLNRDGKVD
                     IVDLDYVQKNLGQSEDAKSLESIVSTNPIVDTSKVELKGNSDVDINGNVENLFSGENN
                     GVTISSKNDEISEEKPAVMDIALSEALNMEVINIKAPEGTAPAKGIVEVTDKDGNVQQ
                     IPYENKEYMKNLKDEEQQEEVNNEQEEVNQEEVNNKDENINQTDNNSNNKDENNDKQQ
                     ENSDKQEANSNTNQDKNNDKENSSMDKPNSDEDTPKEEGNISKDDNSTTSTYSRSALE
                     TYADVQNSDIVINLGKQVAVKKITIKITATTANDRNLAEISKVEFLNNVYKEIPKPEM
                     NIPKINKISTSTAVGNEKVSFYWNNEVNVSAYELILDKIDSKGKVLSTKKLQTSKNTI
                     EVRDIEAYGLYRVSIQSLNGDWSSGYKDATPENLDGVPENVDSNYKPIQFSPDSILEF
                     QVVPDTKPEPPEGINVKGKFKSLDVSWKNHKQAKDFDLYYKEKGSNGSWIKYNDKLIR
                     GTSSKIEGLKDNTTYEVRMTATNHLGTSGMSKTYIGTTESMDAPTTPNYRLINTPKEN
                     GGFGIPTNHIVDVVYPDGYDKSEYSDKNPFDKFNVVDGDFTTHWTFPTYNAAEGTNRG
                     PIITFDKSYTMDTFMATPRFDVSDKTINDFEVRYWDENGQLHNLGDVPFETKTDPVNN
                     NKYVMVRLKEPITATKIQVSVCSSYSYKSNISELKFYEYDSIEDDVRNLFMDGLQVEL
                     KEDVTQEKITELKDRLNTPDKASGEYHPYKTVIERELKLAQDLYNDRATLTDVTTVNQ
                     EINKLGKYKDKNGQYTVNSNNLGMQNDWQALGVAARAGDEITVYVGSKSGKTPKLIYT
                     QYYGESGAYKSGEINLNTGKNVIQLSKLHSLDIECGGSLYIRYAEDTPSGGDIKVRVA
                     GATKIPHLNLNGTINDKSPAGVSESKKKIKAYIEELAKYKDAVKGEPYYPGTNVGNSY
                     GYSEKTGVLNTTDIESDKVTLNVPATAVYQEISKGNSDLNTQVDRLYNSMLAWEQIMD
                     LVYSERGVFKTQDLDGNGTVDDNEFNLTKNDMAPKSRMNIKYQRMFIGAFMYASGLHV
                     GVEYGSVPGLMNGVPFQIDDSGKATGGNLFGWGIGHEIGHVTDIGKMTYSETSNNVLA
                     LLAQTFDDKTHSRLEGSTMDKIYEHVTSNSLGIPSNVFERLGMLWQLHLAYDDDFTGS
                     MLKNNSDADLSNDTFYAKISRKYRALSSSDPINSLPKDQMLVAMASSVVEKDLRDYFK
                     AWGVEITPELNSIMDSKNYEKESRKIQYVNDEARRKILNENIASMAKDTKVSASFSDG
                     IQSGSLVKSNKISIDLDVDKDKDKILGYEIIRSDGNYLDGENGTQVKYRTVGFVDAKG
                     NSKTKFTDNISPLNNRAFTYKVVAYDYHLNPTEEFEVGTVKLSDEGKINKSAWSFITN
                     TVSDGDVRTENDSHGPLQNPEIDNIKDNDASTTYKGKIISKAEWNKDPQKDPDINVEE
                     NPYIIVDMKETLPIVGLKYTKPETEARKFSLKGLFNFRKNTSTTYNPLTNYKIQVSND
                     KKNWEDVSQGTFEYGQDLVGGGKDQDNEARVTFNKDGKLWTYQARYVKLISNNKSNIE
                     VAELDIIGPPGDNIEIGIINNADETRTNGIGKLAEDYVYQSDDSSTSEDETGKIPAGS
                     IVITGEYSGNPAFNLPLLIDKNNKTISGEALLFAEVPEKGELGEISKGTWVYYMPKEN
                     FDSLSDKVKAELYRYNDLQGDTPVGQRFVSDTMYVPVGAKNYDELKTISLTDSNSKAR
                     KATRNSIDISNKKVITVSNKVKGNIVRDK"
     regulatory      complement(8393..8478)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(8650..10053)
                     /locus_tag="PC512_003218"
     CDS             complement(8650..10053)
                     /locus_tag="PC512_003218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp9"
                     /protein_id="HDF2442945.1"
                     /translation="MKNSKKILAIGLTLFLVMVNTPMVNALTSVEQIKGNDRYETAAK
                     IADKQNYNTAILINSDNSLADGLSASGLAGALNAPILMTKQNQIPNTTMERLNKAKTV
                     YIIGSESTISKNVENQLLSKKKVVQRIFGENRFDTSIKIAEKIKEIKPIDKVIIANGF
                     TGEADAISASPVAARDGVPIILTDGNSVGFDTTGLKSYALGSSEIISDELVKSTNSIR
                     LGGTDRFETNKIVIQEFYKNSKEFYLSKGLQLTDALAASTIAKNAPVVLVENGSNKSI
                     LSGADKLTVLGGINQNVIKQCINQASPNQQGLYYNPNDRAFKERIKGKVYALTKQYRK
                     ENGVRALSVASRLEGLANDWSNLMANKKTLSHTINGKNSYSTFLKYLDWSEIKPGYIA
                     VQGENIIKYKIPDKPVYTNRDADDIGNFIFNEWKTNPEEGTNMLHKGYEIMGFGIAIT
                     GDKNLYATHEFYGRYKE"
     gene            complement(10515..12410)
                     /locus_tag="PC512_003219"
     CDS             complement(10515..12410)
                     /locus_tag="PC512_003219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp8"
                     /protein_id="HDF2442946.1"
                     /translation="MLSNKKRSMAIVMAGATVMSAAAPIFADNTVTENVDKNYTVSAK
                     DSAKLIEEVRKALEVKFEDTKAGANVNDRVYDIKVDNVNLTNATQLQNKINSLTEGQS
                     LKVTIQDKGHQVLGGKVVDYKIENYKTAQEIVDAVNAYNATLAEDSDNKLTATIKSTN
                     TVEVKRAKDSANVITLNVGDQHLDFSKVITSEEGTFEGYEKSYSDIDSKELHTITVKN
                     ADLQDISAEELFDGIRLTTLGREIVNKVKNGYALTFENEAILTQEQEDSDDKDKPEKS
                     SFDIVLSKANEKPETISVSSKNHKLVRDLHKVLTDVKDGKELKVEVLSGDSRFTTAVE
                     VSKERFKDGEAEAIILVGEDAIVDGLASAPLASQKNAPILLSKKDSLPSEIEAEILRV
                     LGSNLSSKKIYIVGGESKVSKETEEKLSKLGVSKVERVSGEDRFETSLEIAKQLKDTF
                     KTAFVVGGNGEADAMSISARAAQFGAPIIVTGNELDANAEKLLKGKELEIVGGENSVS
                     KEVEDKLVDIDLNNKVERLAGENRKDTNAKVINKYYAGATKAYVAKDGYVGGNGQLVD
                     ALTAAPLAASSKAPIVLTTEELSKSQEEVVELRLKNATKLVQIGEGIAKNAIEKIAEK
                     INLFTKN"
BASE COUNT         3524 a         2337 c         1407 g         5458 t
ORIGIN      
        1 attattttta acttcttttt aaacatattc aaaattgaat ttatatttat atatataaaa
       61 gatatctgct ttatttaaaa ttaaacttaa tatagctcaa attattatac attttaacct
      121 caatattatt agattgttaa gataatgaaa ataaaataag aatgcattta aatatataac
      181 tttatatcta aatacattct tattttctat ttacttaata tttatttttc aattaaactc
      241 ttaatcttgt ctattacaga tgaggctatt cctccaccta cttcaaacaa ctttgatgaa
      301 tttttacctt ttaatgacga ttcttgtgat ttatctaacg tatttgtagc aagtataact
      361 ggtgaattgt ttttagctgc taatggtcca actgctaaag catctataag tttatcttga
      421 tttgcaacta caactccatc tagcttagat tgagagtaga atttatctat tactttggca
      481 ttcgtctctt gtctagtttg acctgccacc ctattgtttg atatatcttt gtttgctatt
      541 tttccaactt gttcaatagc cttgttagat attttttcta ctccaccaat aaaatatata
      601 tttgacacct tatttgattt aataaattgt tcagcttcat tatctacacc atctttttgt
      661 gtaagtacta ttggagtttt ttctttacca gccagtgatg ctattgataa tgaatcagct
      721 tctccatttc ctgctcctat atacaacttg cttacattat tcgtcttatc tatttctttt
      781 gctatattaa tagaagtttg atatcttgta tctccaccta ttctttgtac tgatattttt
      841 gaatttacag ctttgatagc ttcaacaact gaatttggca ttgagttgtt tccacctatc
      901 acaattactt ttgatggatt tagccttttc aattcttcta cagttttttg aggaagcttt
      961 tcatttgatg ataaaagaat tggtgagttt tttacactag caagtggtgt agctgtaagc
     1021 ccatccacca tacttttatc ttctccattt actattacaa ctgtatctga ttttgtccaa
     1081 ccactttgag atattttgat agctgtctca aatctatcag caccttttaa ttttttgact
     1141 gtgacattag atgtagaatc acttgaactt cctcctccag agcttccacc actagatgag
     1201 ccgcctgaat tacttcctcc accattattt ccaccattgc cattatctgg tggtaattca
     1261 tccggttttg ataattcatt ttcaactatg tattctaaac tttttggaag tgtaacttca
     1321 acatatttgt ttattgtagc ttttcttccc ttagttgttt tttgtgctaa tccaagtttt
     1381 aatattacat ttgaaccact ttcttgtgtt tctttactaa caatagaata gtttatccta
     1441 atattgttta ataaatattc aagtgcttca cttttctcta ccttatactt ttcagggtca
     1501 tttttactag aaccagttcc accaattggt tttacttcac tctcattaat aagggtaaat
     1561 attaatcctt catcagagct tatattttca taatccactg ttttgttgtt atatgttaca
     1621 atttttaaag ctggtttatc atttgttcct tttcctaaaa ctttatagtc agcatttgag
     1681 ttactgccag atttttttac agatattctt cctatattca atctatttcc gtctagtaaa
     1741 tcttcatttg atgtaacata tatatctaat gtagttgtat tacttgattt gttgtattct
     1801 actctacaag tagcatttgc atttccactt tttatctgag attttatatt atcagaccaa
     1861 gtaatctttt ctttctgctc attatctact acttcaacct caccttgtac ttttatactg
     1921 gcttgaaatg aatatactat gttttctact gagtccacag atatatctat agtatttact
     1981 ttctcatacg tttttgttcc ttgtaaaact ggagctgcat atgcacatgt agcactacca
     2041 gttacagcta ctgccatagt tgatactgct atagttctta taaaagattt tcttttactc
     2101 attaacaccc gtccttatct atcattaact aagtggataa atttacttat ccacctagct
     2161 tttatattta atttataaat taccctaaat ttatggttac atttatatac tttactttta
     2221 atatctacta ttttaaaact attctagtac ctaatcttat tagatataca atgttagtat
     2281 ttttacgttt ttagagttcc acctactatt tatctctaac aatattaccc tttactttat
     2341 tgcttacagt tataaccttc ttattactga tatcaataga atttcttgta gcttttctag
     2401 ctttactatt actatcagta agacttattg tctttaactc atcataattc ttagctccta
     2461 caggtacata cattgtatca cttacaaatc tttgacctac tggagtatct ccttgaaggt
     2521 cattgtatct atatagttca gccttaacct tatcacttaa agaatcaaag ttttcttttg
     2581 gcatatagta aacccatgta cctttactga tttcacctag ttcacctttt tctggaactt
     2641 ctgcaaataa aagtgcttct ccagatatag tcttattgtt tttatctata agtagtggta
     2701 aattaaatgc tggatttcca ctgtattcac ctgtaataac tattgaaccc gctggaatct
     2761 tacctgtttc atcttcactt gtgctagagt catcactttg atatacataa tcttctgcta
     2821 attttccaat tccattagta cgagtttcgt ctgcattatt tattatgcca atttctatat
     2881 tatcacctgg aggtcctatt atatctaatt ctgcaacttc tatattagac ttattatttg
     2941 agattagttt tacatatcta gcttggtatg tccaaagttt accatcttta ttaaatgtaa
     3001 ctctagcttc attatcttgg tcttttcctc caccaactaa atcttgtcca tattcaaaag
     3061 ttccttgact tacatcttcc cagttctttt tatcattact tacttgtatc ttgtaattag
     3121 ttaaaggatt gtatgttgtg ctagtattct ttctaaagtt aaataatcct tttaatgaga
     3181 actttctagc ttctgtctct ggttttgtat attttagtcc tactataggt aatgtttctt
     3241 tcatgtctac tattatatat ggattttctt ctacatttat atcagggtct ttttgagggt
     3301 ctttgttcca ctctgcttta cttattatct ttcctttata tgtagtactt gcatcattat
     3361 cttttatatt atcaatttca ggattttgta atggtccatg tgagtcattt tcagttctaa
     3421 catcaccgtc agaaacagta tttgttatga atgaccatgc tgatttattt attttccctt
     3481 catctgataa ttttacagta ccaacttcaa attcttctgt tggatttagg tgataatcat
     3541 atgcaactac cttatatgta aatgctctgt tattaagagg agatatatta tcagtaaatt
     3601 tagtcttgct atttcctttt gcatccacaa atccaactgt tctgtatttt acctgtgttc
     3661 cattttcacc atctaaataa tttccatcac ttcttattat ttcgtatcct agtatcttat
     3721 ctttatcctt atctacatct aggtctatag atattttatt agatttaact agagaaccac
     3781 tttgtattcc atcagaaaaa ctagcactta ctttagtatc ttttgccata ctagctatat
     3841 tttcatttaa aatctttctt ctagcttcat catttacata ttgtatcttt cttgattctt
     3901 tttcgtagtt cttgctatcc attatactgt ttaattctgg tgtaatttct actccccatg
     3961 ccttaaagta atctcttaaa tctttttcaa caacacttga tgccattgct actagcattt
     4021 ggtcttttgg taaactatta attgggtcac tacttgaaag tgctctgtat tttcttgaaa
     4081 tctttgcata gaatgtatca ttacttaaat cagcatctga gttattcttt aacattgaac
     4141 ccgtaaaatc atcatcataa gctagatgta attgccataa cattccaagc ctttcaaata
     4201 cattgcttgg tatacctaag ctatttgaag ttacatgctc atatatctta tccattgttg
     4261 aaccttcaag tcttgaatgt gtcttatcat caaaggtctg agcaagtaaa gcaagtacat
     4321 tgttactagt ttcgctatat gtcatctttc caatatctgt aacatgtcct atctcatgac
     4381 ctattcccca tccaaataag tttcctcctg tagcttttcc actatcatct atttggaaag
     4441 gtactccatt cataagccct ggaactgaac catattctac tcctacatgt aatccagaag
     4501 catacataaa tgctccaata aacattcttt ggtattttat gttcatacga gattttggag
     4561 ccatatcatt tttagttaag ttaaattcat tatcatctac agttccatta ccatctaaat
     4621 cttgtgtttt aaatactcct ctttctgagt aaactaaatc cattatttgt tcccatgcaa
     4681 gcatactatt atataatcta tctacttgtg tatttaaatc agaatttcct tttgatatct
     4741 cttgatatac tgctgttgca ggaacattta atgttacttt atcactttca atatctgtag
     4801 tgtttaacac accagttttt tctgaatatc catatgaatt accaacattt gttcctggat
     4861 aatatggttc tccttttaca gcatctttat atttagctaa ttcttctata tatgctttta
     4921 tctttttctt agattcagaa actcccgcag gactcttatc atttattgtt ccatttagat
     4981 taagatgtgg tatcttagta gctcctgcta cacgtacttt tatatctcct ccacttggag
     5041 tatcttcagc gtatcttatg tataaacttc ctccacattc tatatctaaa ctatgaagtt
     5101 tgcttaattg aattacattt tttccagtgt taagatttat ttctccactc ttatatgcac
     5161 cagattctcc atagtactgt gtatatatca acttaggagt ttttccactt ttacttccaa
     5221 catatactgt gatttcatct cctgctctag cagctactcc taatgcctgc cagtcatttt
     5281 gcatacctaa attattggaa tttacagtat actgtccgtt tttatcttta tattttccta
     5341 atttatttat ttcttgattt acagtagtta catcagtaag tgtggctcta tcattatata
     5401 agtcttgagc taattttaat tctctctcaa taactgtctt atatggatga tattctccac
     5461 tagctttatc tggagtattt aatctatctt ttaattcagt tattttttct tgagttacat
     5521 cttcttttaa ttcaacttgt aggccatcca taaatagatt tcttacatca tcttctatac
     5581 tgtcatactc ataaaactta agttctgata tattagactt atatgaatag gatgaacaaa
     5641 cacttacttg tatcttggta gcagttattg gttcttttaa tctaaccatt acatacttat
     5701 tattatttac agggtctgtc tttgtttcaa aaggaacatc ccccagattg tgtaattgac
     5761 cattttcatc ccaatatcgt acctcaaagt catttattgt cttatcagaa acatcaaaac
     5821 gaggtgtagc cataaaagta tccatagtat aagatttatc aaaagttatt attggtcctc
     5881 tattcgttcc ctcagctgca ttatatgttg ggaatgtcca atgtgttgta aagtccccat
     5941 ctactacatt gaatttatca aatggatttt tatcactata ttcacttttg tcatatccat
     6001 ctggataaac aacatctaca atgtgatttg ttggtattcc aaatccacca ttttctttag
     6061 gagtattaat taatctatag ttaggtgttg ttggtgcatc catgctttca gttgtaccta
     6121 tatatgtttt agacattcca ctagttccca agtggttagt agctgtcatt ctgacttcat
     6181 atgttgtatt atccttaaga ccttctatct ttgaacttgt cccacgaata agcttatcat
     6241 tgtattttat ccaagaccca ttagagcctt tttctttata gtacaagtca aaatctttag
     6301 cttgtttatg atttttccag cttacatcaa gagatttaaa tttaccttta acatttatac
     6361 cttctggtgg ttctggtttt gtgtctggaa caacttgaaa ttctaatata ctatctgggc
     6421 taaattgtat aggtttatag tttgaatcta cattttctgg tactccgtct aagttttctg
     6481 gtgttgcatc tttataacca ctagaccaat ctccatttaa agattgtatg ctaactctat
     6541 atagtccata tgcttctata tctctaactt ctattgtatt tttactagtt tgtaattttt
     6601 tagtagataa tacttttccc ttactatcaa ttttgtctag tataagttcg tatgctgata
     6661 catttacttc attattccaa taaaaagata ctttttcatt tccaacagca gtgctagtcg
     6721 atattttatt tattttaggt atgttcatct ctggctttgg tatttcttta tatacattgt
     6781 ttaaaaattc aacttttgat atttctgcaa gatttctatc gtttgctgtt gtagctgtta
     6841 tttttatagt tatctttttt actgctactt gtttaccaag atttattact atatcactat
     6901 tttgaacatc tgcatatgtt tctaatgctg acctactata tgtagatgtt gtagagttat
     6961 catctttact gatattaccc tcttcttttg gagtatcttc atctgaatta ggtttatcca
     7021 ttgatgaatt ttctttatca ttatttttat cttgattggt attagagttt gcttcttgtt
     7081 tatcgctatt ttcctgttgt ttatcattat tttcatcttt attatttgag ttattatcag
     7141 tctggtttat attttcatct ttattattta cttcttcttg atttacttct tcttgttcgt
     7201 tatttacttc ctcttgttgc tcctcatctt ttaagttttt catatattct ttgttttcat
     7261 aaggaatctg ttgaacatta ccatctttgt cagtaacctc aactattcct tttgctggag
     7321 cagtaccttc tggagctttt atattgatga cttccatatt aagtgcttct gataaagcta
     7381 tatccattac tgctggtttt tcctcagata tttcatcatt ttttgaagat attgtaactc
     7441 cattattttc tccactaaat aaattttcta cattaccatt aatatctaca tcactatttc
     7501 cttttaattc aaccttactt gtatctacta taggattggt agatactata ctttctaggc
     7561 tttttgcatc ttcactttgt cctaaatttt tctgtacata atctaagtca acaatatcta
     7621 cctttccatc tctatttaaa tcaaattctc ttttatttga atctatattc tctaaaacct
     7681 tattataatc actcttatct actttaccgt ctccatttac atcacccatt aagaacaatt
     7741 cataatttaa aggtttattt ttattatcta cacttgctct attgcttaat aagactcttt
     7801 gtgaataact tgatatatca atgtctttaa tttctttgtt cttaaatcca tctccagaga
     7861 cttctacatt gtattttcca acaggtaaat tattaaatac aatattataa tatgatatat
     7921 tctcatcttt attttttatt tcacttctac ttgcagataa tttttttata gtatattcta
     7981 tattatctgt cccaacattt actgttcctg aatctttttc tccaagcttt attattccac
     8041 tattgttact atcatctttt aatcgtaact gcatattagt catactttct gactcgctat
     8101 tttttattgg cagtgaaaaa tttaaatcta cttcaagact cccccttaac ttttctgtaa
     8161 ctgatttttc aactgccctt agcttcccct ctaatatagg ttctgcaaaa acgtttagtg
     8221 gtgcactaca catagatact gctagtacac aagatattgc ctttttcatg aaataacaat
     8281 cctcccttaa taaatatcta atttttcatg aatttaaata ctataagttt cagacaataa
     8341 aaaaagacac tcaaagagaa tcttaattat aaaataaaaa gactttactc tttttagcaa
     8401 ctggctgata tggctttaaa agctttaatc cctatagttt tgcgtcatta gatttcccta
     8461 attttgccat ttaattttca ctactttctt acccatttta tactatattt aaacttttta
     8521 atataatttt tttagattaa attataaaaa aataacattt atattaattt attaatataa
     8581 atgctatttt ccattataat ttaattattt atatagcttc cttacaagca taattttgtg
     8641 tatattttct tattctttat atcttccata aaattcatgt gtagcatata gattcttatc
     8701 tcctgttata gctataccaa atcccattat ttcataccct ttatgcaaca tattagttcc
     8761 ttcttctgga tttgtcttcc actcattaaa aataaagttt cctatatcat ctgcatctct
     8821 atttgtatat acaggtttat ctggaatttt atatttaatt atattttcac cttgaactgc
     8881 tatatatcca ggtttaatct cactccaatc taagtatttc aaaaaagtag aatatgaatt
     8941 ttttccattt atcgtatgag ataaagtctt cttatttgcc attaaattag accaatcatt
     9001 tgctagaccc tctaatctgc ttgctacaga taacgctctt actccattct cttttctata
     9061 ctgctttgta agagcatata ctttaccctt tattctctct ttaaatgctc tatcatttgg
     9121 attgtaatat aaaccttgtt gatttggtga agcttgattt atacattgct tgataacatt
     9181 ctgatttatg cctcctagta cagtcaattt gtctgcacca cttaaaatac tcttgttact
     9241 gccattttca actaaaacta caggagcatt ttttgctatt gtagaggcag ccaaagcgtc
     9301 tgttaattgt aagcctttac ttagataaaa ttctttacta tttttataaa actcttgtat
     9361 aactatctta ttagtttcaa atctatctgt gccacccaat ctaatagaat ttgtgctctt
     9421 aactaattcg tcgcttatta tttcactaga accaagcgca taactcttta agcctgtcgt
     9481 gtcaaatccc acactatttc catctgtaag tattataggt actccatctc tagcagctac
     9541 tggtgatgca cttatcgcat ctgcttctcc tgtaaatcca ttggctataa ttactttatc
     9601 tattggctta atttctttga ttttttcagc tatttttata cttgtatcaa atctattttc
     9661 accaaatatt ctttgtacaa ccttcttttt ggatagtaac tgattctcaa catttttact
     9721 tattgttgat tctgaaccta ttatatacac agtctttgct ttgtttaatc tttccatagt
     9781 tgtgtttgga atctggtttt gttttgtcat caaaataggc gcatttaagg ctccagctaa
     9841 accacttgca cttagaccat ctgctaagct attatctgag ttgattagta ttgctgtatt
     9901 gtagttttgc ttatctgcta tttttgctgc tgtctcatat ctgtcattcc cttttatttg
     9961 ctcaactgat gtcaacgcat ttaccatagg agtatttacc attactaaaa atagtgtaag
    10021 tcctatagct aatatctttt tactattctt catattattt tctaccccca atgtactttt
    10081 catatttttt attagtactc atacttattt ttaatcaaaa gttacaattt tgttaccata
    10141 ttttatatat gataccatag ttatccatac aactcaaaca atatacctaa agtttttatt
    10201 ctctataaat tcaaaacatt ataatttatt ttatttaatt acgttataag ttcaaaataa
    10261 tttatgttag taatatgttt aatcattata agaagtatct ttttataata atttttgcaa
    10321 tatgaatttc tcaacattat aatcaaaaaa taaaataagg tatctcaatc taattctaaa
    10381 tgagacacct tatttttatt attttatctt gttatttgta tattttataa tatctacact
    10441 atgtcttaca tattaacgca ttgtataatc atatattatc taaataaact tttaatatta
    10501 attcctatat cttattagtt cttagtaaat aagtttattt tttctgctat tttttcaata
    10561 gcgtttttag ctattccttc acctatttgt actaacttag tagcattctt aagtcttaac
    10621 tcaactactt cttcttgtga tttagaaagt tcttctgtag ttaatactat tggagccttt
    10681 gaactagctg caagtggtgc tgctgtaagt gcatcaacta attgtccatt tccacctaca
    10741 taaccatctt ttgctacata tgctttagtt gcacctgcat agtatttatt gattacttta
    10801 gcattagtat cttttctatt ttctccagct aatctttcaa ctttattatt taaatctata
    10861 tcaactaatt tgtcttcaac ttcttttgat acagaatttt ctccacccac tatttctaat
    10921 tcttttcctt ttaataattt ttcagcattt gcatctaatt cgttacctgt aactattatt
    10981 ggagcaccaa attgagcagc tctagctgat atactcatag catcagcttc tccatttcca
    11041 cctactacaa aagcagtctt aaatgtatct tttaattgtt ttgctatttc taaagaagtt
    11101 tcaaatctat cttctccaga aactctctca actttactta cacctaattt agaaagtttt
    11161 tcttcagttt cttttgatac tttagattct ccacctacta tatatatttt cttagaagat
    11221 agattacttc caagtactct taatatttca gcttctattt ctgatggtag tgaatctttt
    11281 ttagataata atattggtgc atttttttga gaggcaagtg gtgctgatgc taatccatca
    11341 actatagcat cttctccaac taaaattata gcttctgctt ctccatcttt aaatctctct
    11401 ttactaactt ctactgctgt tgtaaatctt gaatcaccag ataaaacttc tacttttaat
    11461 tcttttccat cttttacatc agttaatact ttgtgtaagt ctctaactaa cttatggttt
    11521 ttacttgaaa cacttattgt ttctggcttt tcatttgcct tgcttaaaac tatatcaaag
    11581 cttgattttt ctggtttatc tttatcatca ctatcttctt gttcttgagt aaggattgct
    11641 tcattttcaa atgttaaagc atatccattt ttaactttat taactatttc tcttcctaat
    11701 gtagttaatc taattccatc aaataattct tctgctgata tgtcttgtaa atctgcgttt
    11761 ttaactgtta tcgtatgtaa ttcttttgaa tctatgtcac tataactctt ttcataacct
    11821 tcaaaagtac cttcttctga tgttatcact tttgagaaat ctaaatgttg gtctcctaca
    11881 tttaatgtaa taacatttgc tgaatctttt gctcttttta cttcaactgt atttgtagat
    11941 tttatagttg ctgttaactt gttatcagaa tcttctgcta aagttgcatt gtaagcatta
    12001 actgcatcta ctatttcttg agcagttttg tagttttcaa ttttatagtc aactactttt
    12061 ccacctaaca cttgatgccc tttatcttga atagtaactt ttaaactttg cccttctgtt
    12121 aaagagttta ttttattttg taattgagtt gcattagtta agtttacatt gtctactttt
    12181 atatcgtaaa ctctatcatt tacatttgct cctgcttttg tatcttcaaa cttaacttct
    12241 aatgcttttc taacctcttc gattagttta gcagaatctt tcgcacttac tgtgtaattt
    12301 ttatcaacat tttctgtcac ggtattgtct gcgaatattg gtgctgctgc actcataact
    12361 gtagcacctg ccattactat tgccatactt ctctttttgt tgcttaacat atttatgtcc
    12421 tccgaatatt attttttatt ttttatattc gtatttccca cacataaata atattatata
    12481 taatattatt tttcaatata ttttatgtgt ttacataatt tactaacaca aacactaata
    12541 atatcttctt gaaacccttc cccctactta ggctctctat aattatgctc aaagatagaa
    12601 atcctatttt atagtgattt tctactaaac aatcatatac taacaaaagt attcaaactc
    12661 catttttata tactactatg cactaatttt tgctttactc ttattactta aatatatatc
    12721 actaaa
//
LOCUS       DAMJVG010000100        11961 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.104, whole genome shotgun sequence.
ACCESSION   DAMJVG010000100 DAMJVG010000000
VERSION     DAMJVG010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11961)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11961)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11961
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.104"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            125..508
                     /locus_tag="PC512_003220"
     CDS             125..508
                     /locus_tag="PC512_003220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HDF2442947.1"
                     /translation="MNLSKKIEDKRKAKQRAEKVKKAKIATAGVVLGAVTGAVSGVLL
                     APKSGKETREDIKDASQQIAEKINMKTVDVKGKVSEKLEDKKGNFIESKKKIKKYIDN
                     KKSVENSSEEDKIIDIVEPVSVTEE"
     gene            510..860
                     /locus_tag="PC512_003221"
     CDS             510..860
                     /locus_tag="PC512_003221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442948.1"
                     /translation="MDNTITINISIIYVLLAILACIALVYLIIVLVKLHKILNNVGTM
                     LNENTQNINTTLNNLPNVVETFGEVGENMKDVTEVVTEVTADFLVTKDSVKSNMDVIV
                     DILTIIKNIFVDKK"
     gene            complement(961..1419)
                     /locus_tag="PC512_003222"
     CDS             complement(961..1419)
                     /locus_tag="PC512_003222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442949.1"
                     /translation="MIRTKVVELIATVCRENKPHKWVDENYTPYDKSGKVELMSIEDL
                     NELISSSGRADFLYSSRLQKLLNEVYINQSRASYISGCGLFWSSYWDILEEKFEEWLY
                     NSYIFFDEDDEYLEGMEDFELECKDVLMDVIETTSIDIYVQMIKRNITNY"
     gene            complement(1464..2252)
                     /locus_tag="PC512_003223"
     CDS             complement(1464..2252)
                     /locus_tag="PC512_003223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF2442950.1"
                     /translation="MKVVIIPGHTLIGKGTGAVGYINESKETRILNDLIVKWLKIGGA
                     TVYTGRVDESSNHLADQCAIANKQETDLAVQIHFNSNATTSTPVGTETIYKTNNGKTY
                     AERVNTRLATVFKDRGAKSDVRGLYWLNHTIAPAILIEVCFVDSKADTDYYVNNKDKV
                     AKLIAEGILNKSISNSQGGGENKVYENVIVYTGDADKVAAQILHWQLKDSLIIEASSY
                     KQGLGKKVYVVGGEANKLVKGDVVINGADRYETVKLALQEIDKL"
     gene            complement(2391..2828)
                     /locus_tag="PC512_003224"
     CDS             complement(2391..2828)
                     /locus_tag="PC512_003224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HDF2442951.1"
                     /translation="MNKKLENRCSWQEYFMRLCETVAERGTCDRAYVGAIIVNSENRI
                     VSTGYNGSISGDKHCSEVGHEMRDGHCIRTIHAEQNALYYCAKEGISVKNCSIYVTHF
                     PCLNCTKAIIQAGIKHIYYRTGYRIDEYAIKLLQSSNVLYTKL"
     gene            3650..4159
                     /locus_tag="PC512_003225"
     CDS             3650..4159
                     /locus_tag="PC512_003225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2442952.1"
                     /translation="MLSENIKTIRKSKGLSQQELAIKLNVVRQTISKWEQGLSVPDSD
                     MLISISEVLETPVSTLLGETIVESEVDNLKVISEKLEIINLQLAQRKNMRRKMFHWLF
                     ILLCAVILIVFVVLGRLNSPYLDWNYTDPETAVFGVAFHAFEWLFVRLVPIVLIGAII
                     GIFLTRKKI"
     gene            4573..5004
                     /locus_tag="PC512_003226"
                     /pseudo
     CDS             4573..5004
                     /locus_tag="PC512_003226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016295744.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            complement(5191..5384)
                     /locus_tag="PC512_003227"
                     /pseudo
     CDS             complement(5191..5384)
                     /locus_tag="PC512_003227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
     gene            5486..5992
                     /locus_tag="PC512_003228"
     CDS             5486..5992
                     /locus_tag="PC512_003228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HDF2442953.1"
                     /translation="MKNEKKITVALLIVYLLILSWIILFKLQFSFSALDHIRQINLIP
                     FGGSVIANGKIDFDEIINNAIVFIPVGAYFSLLFKNKSVLKAIGSVLGISFVYEIIQF
                     IFAIGASDITDLISNTLGGIIGIALVYVLSIVLKDKTHKILNRIAIVCTVLVVAFLFM
                     LLAVNNIF"
     gene            5997..6273
                     /locus_tag="PC512_003229"
                     /pseudo
     CDS             5997..6273
                     /locus_tag="PC512_003229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436830.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4865 family protein"
     gene            6542..7114
                     /locus_tag="PC512_003230"
                     /pseudo
     CDS             6542..7114
                     /locus_tag="PC512_003230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902350.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            7217..8032
                     /locus_tag="PC512_003231"
     CDS             7217..8032
                     /locus_tag="PC512_003231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HDF2442954.1"
                     /translation="MFKIGEFSKLTQVSTRMLRYYDETGLLKPAKIDSLTGYRMYSAE
                     QISTLNRIIYLRDSGFNVAEIALALNFSNNAIIEQLDRKSIEIMDNIQKEQEKLKKIE
                     IAKKEVLHGKSELYFNITIKEIPSYCVLSLRKEIPNYYYEGELWKELSAFAKENKINI
                     SDETFSIYHNEEYKEKDVDVELCAIVNKIGKATGDFKFRFTEPVSMMACTMVYGDFSN
                     ISYAYRSFAKWLQENSQYKMKGSSRQIVHRGPWNEKNPENYLTEIQIPLENLL"
     gene            8113..8589
                     /locus_tag="PC512_003232"
     CDS             8113..8589
                     /locus_tag="PC512_003232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002608187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HDF2442955.1"
                     /translation="MTTYKVNSIGTICNNEKGAFIQLEAPYILALRALDGFSHINVLW
                     WFSDFDNTNFRSVLETEQPYKNAPEKMGIFATRSPVRPNPIALSAVEIIDIDYMSGLI
                     QIAYIDANDKTPILDIKPYTPSLDRVENPQVPDWCSHWPHSLEESASFAWESEFNF"
     gene            8603..9166
                     /locus_tag="PC512_003233"
     CDS             8603..9166
                     /locus_tag="PC512_003233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2442956.1"
                     /translation="MSLQDYIFEKPVIETEHLILRTMNKNDIDDLKEWISDISLYEYW
                     GKRPSKSEKNPELLFDKSKKSTKSFHWGIVHKQDSKVIGEIWIYLIENNRMAKVAFRL
                     SKHYQGNGLMSEVLKNVIEFCFSKTELQKIWTDVHILNHASYKTLEKVGFQREGHIRG
                     GKMVNTYCDYYLYGILKSDYITRWCYG"
     gene            9421..10332
                     /locus_tag="PC512_003234"
     CDS             9421..10332
                     /locus_tag="PC512_003234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF2442957.1"
                     /translation="MYAYENIEMSLNYIEQHLSEKIETEKLAEIACLSTFYYQRLFKR
                     LVKKSVQEYIKLRRLAMVIAELNNSEERILDIALKYGFSDHANFTRAFKEVYHITPDE
                     YRKNVPMLNTFDKPELSSRYIMIDENVPLIVGNIVLEIQRKTLRTKETYFGFEKTVNI
                     SEQIPAGESTGIDVPGQLWREFHAKKLQTENAIFNNDIELGVSHLASPDKGTFLYFAG
                     GMVSSTDVCPKNMVQHTLPAGEYIVCKIEAESFEELVTTALNQANKYLFETWLPNHNL
                     VTKPFMAEKYYKGNAEINYMEIWIIPV"
     gene            10410..10844
                     /locus_tag="PC512_003235"
     CDS             10410..10844
                     /locus_tag="PC512_003235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HDF2442958.1"
                     /translation="MINIKDINYVPNISEISVYIENSAFDELYQHMNNEYKAVCKIEY
                     SKDVWARGWNVKFKKSGKSLCVVYPKKNYFTVLVVVGNKEKEDVENLLPRLSEYVQEI
                     YRNTREGNGQRWLMIDLKSKNNVYQDVLRLIEIRYAIKCVKP"
     gene            11312..11961
                     /locus_tag="PC512_003236"
                     /pseudo
     CDS             11312..11961
                     /locus_tag="PC512_003236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009243519.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
BASE COUNT         4251 a         1742 c         2051 g         3917 t
ORIGIN      
        1 taatgaatag gaagtaatta aaaagaattt ttattgattt ttaaaaattt agttagaaac
       61 tatatcatta tggtaaaaaa tgtattataa tgtttagaaa tattataata aggagcgatt
      121 aaacatgaat ctatcgaaga aaatagaaga taaaagaaaa gctaaacaga gagctgaaaa
      181 agttaagaaa gctaaaattg ctacagctgg tgtggtatta ggagctgtta ctggtgcagt
      241 gagtggagta cttttggctc ctaaatctgg aaaagaaaca agagaggata taaaagatgc
      301 ttcacaacaa attgctgaaa agataaatat gaaaactgta gatgtaaaag gcaaagtatc
      361 tgagaagcta gaggataaaa aaggaaactt tatagaatca aagaaaaaaa taaaaaaata
      421 tatagataac aaaaagagtg ttgaaaattc tagtgaggaa gataaaataa tagatatagt
      481 tgaaccagtt agtgttactg aggaataata tggacaatac aataacgatt aacataagta
      541 taatatatgt attattagct atacttgctt gtattgcttt agtttattta attattgtac
      601 ttgttaaact acataagatt ttaaataatg ttggaactat gttaaatgaa aatactcaaa
      661 atataaatac aactttaaat aatcttccta atgttgtaga aacttttgga gaagtaggag
      721 aaaatatgaa agatgtaaca gaagtagtta ctgaagttac agcagatttt cttgttacta
      781 aagacagtgt caaatcaaat atggatgtta tagttgatat attgactata attaaaaaca
      841 tttttgtaga taaaaaataa taagttaata taaaataagc ctataagata taatttaaac
      901 gaccttaaaa tagcatttat aaggtcgttt tttattagct tgatttgaca ctatgtgttt
      961 ttaataattg gtaatattcc tctttatcat ttgaacatat atatctatgc ttgttgtttc
     1021 aattacatcc ataagaacat ctttacattc aagctcaaaa tcttccattc cttctaaata
     1081 ttcatcatct tcatcaaaaa agatataaga attatatagc cattcttcaa atttttcttc
     1141 aagtatatcc caatacgaac tccaaaataa tccacaacct gatatataag atgctctact
     1201 ttgatttata taaacttcat ttagaagctt ttgtaatcta ctgctataaa gaaaatctgc
     1261 tcttccactg cttgatatta attcatttaa atcttctatt gacattaatt caactttacc
     1321 acttttatca taaggagtat aattttcatc aacccattta tgtggtttgt tttctctgca
     1381 tactgttgct atcaactcta caacttttgt tcttatcatt tttttatcct aacttattta
     1441 ttttttataa aataatcatg attttataat ttatctattt cttgtaatgc taatttaaca
     1501 gtttcatatc tatcagcacc atttattact acatcacctt ttacaagttt attagcttct
     1561 ccacctacaa cataaacctt tttacctaaa ccttgcttat aactagacgc ttcaattatt
     1621 aaagaatctt tcaattgcca atgtaaaatc tgagcagcca ctttatcagc atcacctgta
     1681 taaacgatta cattttcata cactttattt tcccctcccc cttgagaatt tgatatagat
     1741 ttgtttagta taccttctgc tatcaattta gcaactttat ctttattatt aacataataa
     1801 tctgtatctg ctttactatc tacaaaacat acttctatta atattgctgg tgcaatagta
     1861 tgattaagcc aataaagacc tctaacatca gactttgcac ccctatcttt gaatactgta
     1921 gctaacctag tattcactct ttctgcatag gttttgccat tattagtctt atatattgtt
     1981 tctgtcccta ctggagttga agttgtagca tttgaattaa aatgaatctg aacagccaaa
     2041 tcagtttcct gtttatttgc tatagcacat tggtctgcta aatgattact tgattcatca
     2101 actcttcctg tataaacagt agctccacct attttaagcc atttaacaat taagtcattc
     2161 agtattcttg tttctttgct ttcgtttata tacccaacag ctcctgtacc ttttccaatt
     2221 aaagtgtgcc ctggtattat tactactttc aaactaacat ctcctttaca attaaattta
     2281 acttctattt aatatatgca taacctagaa ttttgtttct ttttatatct tatactttta
     2341 ttataaccca ttttgtaaaa atatagaata ttaagtaaat aatgttaaaa ttataatttt
     2401 gtatataaga cattacttga ttgcaataat tttatagcat attcatctat tctatatcca
     2461 gttctataat atatatgttt aattccagct tgaattatag ccttagtaca atttaagcat
     2521 ggaaagtgag ttacataaat agagcaattt ttaactgaaa taccttcttt tgcacaataa
     2581 taaagggcat tttgttcagc gtgaatggtt ctaatacaat gtccatctct catttcatga
     2641 ccaacttcac tacaatgctt atctccagaa atactaccat tatatccagt agacactatt
     2701 ctgttttctg aattgacaat tatagctcct acataagctc tatcacaagt tcctctttca
     2761 gctactgttt cgcacagtct cataaaatat tcttgccatg agcatctatt ttcaagtttt
     2821 ttattcaaat catatacctc caaaatttat atctaatata taagatttat accttaaaaa
     2881 taatattaaa aacaaattta tatgataaat aaaatttatt aatactgttt ttagtctaaa
     2941 ttatttcatt ttaaattaaa gttacaagga atctaagatt atatatatct ttcttcgtaa
     3001 tatgaatgtt acaatataaa aaactgtctc aataaaatag agacagtttt acagtcaaag
     3061 tttataatac aagttcatat ttttctttaa attcttttac agcttcgggc catgcctttt
     3121 gttctgtaat acctttttct ttagctattt taattgcaat ctctcttatc attgcagcgc
     3181 cttctaatat tcccattttt aatctccctt caaatatctt tttgtataga atataaatag
     3241 tgctaagatt tattacatgc tgcatataca atatctatac aacacataac ttgtaaattc
     3301 cttttatttt catacgtctt taaccgacat ataattatat tcaataagtt ttaaaattat
     3361 gaactcaatt ataattattt ttattttttt agaatctaaa cactaaaaat tgtaggtaaa
     3421 tttgtcttat gcctttataa atatttctac agttttaatt actggacata tctattttta
     3481 ttataaaaag cgattaaaaa tggagaatat cctcataaaa actatatata agcaaaacgg
     3541 ttaaaggaaa aagaagaaat ttacttgaat gttaaaatgc gttgcttgaa gcaatgggca
     3601 gttttgccta taatatcggt aacaactgaa agaaaggtgg ttagccctaa tgttaagcga
     3661 aaacattaaa acaatcagga agtcaaaagg actttcacaa caagaacttg ctataaaact
     3721 gaatgtagtg cgacaaacaa tatctaaatg ggaacaagga ctgtcggttc ccgattctga
     3781 tatgttgatt tccatatcag aggtgcttga aacgcccgta agcactttac ttggagaaac
     3841 tattgttgag tcggaagttg ataacttaaa agtgatttct gaaaaattag agattataaa
     3901 cttgcaactt gcacaaagaa aaaacatgag aagaaaaatg tttcattggt tatttatttt
     3961 attatgtgca gtcatattaa tagtttttgt ggtcttaggg agactaaata gtccttactt
     4021 ggattggaat tataccgacc ctgaaaccgc tgtttttgga gtagcttttc atgcttttga
     4081 gtggctattt gtcagattag taccgattgt ccttatagga gcaattattg gaatcttttt
     4141 gacacgtaag aaaatatgaa gtaactctgc tttttataat acagcaagcg ttccttaaaa
     4201 gcgtcattct acatggcaat cgaggacgac tatgtaagga agaacctttt tgatttccaa
     4261 ctaagcgaag ttattgagga cgacagtagg cccaaaaccg cattaagtaa agtacaggaa
     4321 gcaagactgc tggacttata ctctcatgcg tcagatgcag gaaatgcgag gtctggtagc
     4381 atgatttaca acgatttgta caacgactac gagtagaaat atatggagat aagtattatc
     4441 tacgaaatca gaaaagaaat gacttgataa tttactcatg ttataattat tgatgtgaaa
     4501 ttaataaatc gaaattcctt ttttggattt aacaatactg agtaaggaaa aagtgaatta
     4561 cttttgcaag gaggtgttat ttggatggtg ctagcaggta ttttgattgt agtacaaggc
     4621 tttttgactg gtcctttagc aaaaaaaatt ggtgagaagc gactaatact gataggtatg
     4681 ttttgcaaag ccttagtagc gtttgccatg gtattgacaa ctgggtttgt tagtgtgttg
     4741 gtggtttttg gcttatttgc ggtatcttct gctattacag tacccacatt aaacgcaacc
     4801 ctttcaaaaa ctgacaatca gcataaagga acactgatgg gatttgccag taccgccgga
     4861 aatcttagca aagttattgc tcctttatta actgggtatc tgtatgaaag caatattgaa
     4921 ttaccatata taaccacggg agggatagcc ttaatcggag tggttatctg ctatatctgg
     4981 ataaaaaatc aaaagaacaa atgatggaag aggacgttta tatggaggtt atacacagta
     5041 actaatctgg tatagaaatt caattgaggc ttttctgctt tattaaagtc ttgctactac
     5101 ttaaccctat aatatcctta attcattatg acaaattcca attcaacagt tttgatacac
     5161 ataaggaggt aacaatacta tggaaaatta tcaatgaagt gctaattctt tatcagtgaa
     5221 gttatccata agtttttcta cctgtaatcg tctggtgctt tttgccagat cattggtagg
     5281 taagaaaaat tcatcaacag acacatgaag taatgataca aggtcacttg tatgcttgga
     5341 tgttgccctt tattttcaat attagttaag taacgtgggt caatatttgt aattcgattt
     5401 tagggaaata tttaaagaaa tattttcgtt ttatttcttt aaatcttcaa gaatattgat
     5461 agttttttga aagtaggtgt gtattatgaa gaatgagaaa aaaattacag tcgcattgct
     5521 cattgtttat ttattgattt tatcatggat tattttattt aagctacaat tttcattttc
     5581 tgcgttagac cacataagac aaataaactt aattcctttt ggtggttcag ttattgcaaa
     5641 tggaaaaatt gacttcgatg aaattataaa caatgccatt gtttttatcc ctgtaggtgc
     5701 atatttcagt ttgcttttta aaaataaatc tgttctaaaa gcaataggtt ctgttttagg
     5761 aattagcttt gtatatgaga taattcaatt tatatttgct atcggagcaa gtgatattac
     5821 agacttaatt agcaacacat tagggggtat aattggaatt gcattagtat atgtattatc
     5881 tattgttcta aaggataaaa cacataagat attaaatcga atagcaatag tatgtactgt
     5941 attagtagtt gccttcttat ttatgcttct tgctgtaaat aatatatttt aatgccatgt
     6001 taattacatg ttgttttgga aaagacttta atctgtcaaa gtttgctttt gaaattgaac
     6061 atgaaattac accaatggaa caaatgaaag ctataaattt ttcattggag aaagatgact
     6121 gtacaagtaa agtattaata tacaatccag acaaatggaa atatgtagaa tactatttct
     6181 ataaagatag acctattaaa aaaactattg gaaaaattta ttcaattttg catttgtcac
     6241 aataaaatat gttttgaaat attgaatact taaatatgca aaaaaacaaa tgtaactggc
     6301 tatggggcta tatctactaa aaagctatgt gataggttgg gattaaattt aaacatcact
     6361 tctagaaggc atgaatacac aaggctgaca aactatacag ttatgattaa acgataccaa
     6421 cgggattgaa aatttcgtga agaactttga gaagtcctat tacacatgag caacagcaac
     6481 gaagctattg aagcaaggac gcaggcaatc tagcggttat ctgacaaagg agttgtagga
     6541 cttgaatgta gatactatca gaacggatat accgaccagc tctgcggtta cagatgtgat
     6601 tgtgtagaat atcgagcagt cgggaacgga cactttatct gctacctacg aagtagatca
     6661 gcagataaaa gagagagaac agacaacagc ggtcaaggca acctataccg taaaagtcca
     6721 tgtggacgct gacggggata tggtaatcgt tcagaacctt actcttgcac cagcaatcga
     6781 aaaatcagac tatgagccaa agatatcaga aacagacgca agcgtggacg ctgataccgt
     6841 taatgacgct accgcatttc tggaaacatt ctttgaggtg tacccgacag ccacagaaaa
     6901 agaacttgcc tattatgtat cggaaaatgt gattgaacct atcggcaggg actaccttta
     6961 ttctgaattg gtaaacccag tctttacaaa ggacggggac aatgtgaaag tcaaggtagc
     7021 tgtgaaattc cttgataatc agacaaaggc aacgcaggtg tcgcagtatg atcttgtact
     7081 ccaaaaggat agcaactgga agattttagg ataacatgga aatgggcttg tatcataatt
     7141 atagtgtgca agcccttttc atattgaagt atcaataatc aataattata attaggtaca
     7201 tgaatggagg gataaaatgt tcaaaattgg tgagttttca aaattgacac aagtttctac
     7261 tcgtatgttg cgttattatg atgaaacggg tttattaaaa cctgctaaaa ttgattcatt
     7321 aactggatat cgtatgtatt cagcagaaca aatctcaact ttaaatagaa ttatatattt
     7381 acgtgatagt ggcttcaatg tcgctgaaat tgcattagcc ctcaatttca gtaataatgc
     7441 cattatagaa cagcttgata gaaagtctat tgaaattatg gataatatac aaaaagaaca
     7501 agaaaaacta aagaaaattg agattgctaa aaaagaagtg ttacatggca aaagtgaatt
     7561 gtattttaac ataaccatta aagagatacc gagttattgc gttttatctt taagaaaaga
     7621 aataccaaat tattattatg agggcgaact ctggaaagaa ctctctgctt ttgctaaaga
     7681 aaataaaata aatatttctg atgaaacatt ctcaatatat cacaatgaag aatataaaga
     7741 aaaagatgtt gatgtagaat tatgtgccat tgtaaataaa ataggaaaag ctacaggaga
     7801 ttttaagttt cgttttaccg aaccagtttc tatgatggct tgtactatgg tatatggaga
     7861 tttttctaat atttcttatg cttatcgttc atttgcaaaa tggcttcaag aaaacagtca
     7921 atataagatg aaaggttcaa gccgtcaaat agttcatcgt ggaccgtgga acgagaaaaa
     7981 tccagagaac tatctaacag aaatccaaat tcctttagaa aatctcttgt aaaaaatgat
     8041 aatctgcctt gactttaaca tggtgttaag gtttatcgtt tatttatcaa gaagaaaacg
     8101 gaggaaaata taatgacaac ttataaagta aattcaatag gtactatctg caacaatgaa
     8161 aaaggtgctt tcattcaact agaagcacca tatattctag cattaagggc attagacgga
     8221 ttcagtcata taaatgtttt atggtggttc agtgattttg ataatacgaa ttttagaagt
     8281 gtattggaaa cagaacagcc ttataaaaat gctccagaga aaatggggat ttttgcaaca
     8341 aggtcgccag tacgcccaaa tccgattgct ttatcagcag tagaaattat cgatattgat
     8401 tatatgagtg ggctgataca aattgcttat attgacgcta atgacaaaac gcctatcttg
     8461 gatattaaac catacacgcc gagtttggat agagtggaaa atccgcaagt tccagattgg
     8521 tgtagtcatt ggcctcacag cttagaagaa tctgcttctt ttgcatggga aagcgaattc
     8581 aatttttaag gagtgatgaa ccatgagttt gcaggactac atttttgaaa aaccagtaat
     8641 tgaaacagaa catcttattt taagaacaat gaataaaaat gacatagatg atttgaaaga
     8701 atggattagt gatatttctt tatacgagta ttgggggaaa cgtccctcaa aaagcgaaaa
     8761 aaatccagaa ttactctttg ataagtcaaa aaaatctact aaaagttttc attggggtat
     8821 tgtccataaa caagatagca aagtgattgg tgaaatatgg atatatctta ttgaaaataa
     8881 tagaatggca aaagtggctt tcagactttc taagcattat caaggtaatg gactaatgag
     8941 tgaagtgttg aaaaacgtaa ttgaattttg tttttcaaaa acagaattac aaaaaatatg
     9001 gacagatgtg catattttaa atcatgcttc ttacaagaca ttggagaaag tcggttttca
     9061 aagggaagga catattcgag gggggaaaat ggtaaatacc tattgcgact actacctata
     9121 tggaatttta aaatctgatt atatcactag gtggtgctat ggctaatatt gaagcgacga
     9181 ttggcgaagc aatgaacaat acagttccaa aggtctatga tacgaaaagc attaaaagat
     9241 atgtgatgaa tttattagat atggctcatt aaaaagtacc aaagaaataa aagttaccat
     9301 atagacaaaa ttggtttttt atatcttttg atttcttata agataatggc attgtgcgac
     9361 aagctatgca aaaaattttc atgtatactt tgattataat ttatacaagg aggtactgat
     9421 atgtacgcat atgaaaatat tgaaatgtca ttaaactata ttgaacaaca tttaagtgag
     9481 aaaatcgaaa cagagaaact ggcggaaatt gcctgtcttt ctacatttta ttaccaacgc
     9541 ttgtttaaaa ggttagttaa gaaatcagtt caagagtata tcaaacttcg ccgtttagca
     9601 atggtaatag cagaattgaa taattcagag gaaagaatat tagacatagc tttaaaatat
     9661 ggattttcag accatgctaa cttcacaaga gcatttaaag aagtttacca tattactccc
     9721 gatgaataca gaaagaatgt tcctatgtta aatacatttg acaagccaga actttcttca
     9781 cgttatatca tgattgatga aaatgtccca ttgattgtag gaaatattgt tttggaaatt
     9841 caaagaaaaa cattaagaac aaaggaaaca tattttggtt ttgaaaaaac agtaaatatt
     9901 tctgaacaaa ttcctgctgg agaaagtaca ggaattgatg ttccaggtca gctatggcgc
     9961 gaattccatg caaagaaact gcaaaccgaa aatgccattt ttaacaatga tattgaactt
    10021 ggtgtatctc acttagcaag tccagataaa ggaacattcc tttactttgc aggaggtatg
    10081 gtttcatcaa cagatgtatg tcctaaaaat atggtacaac atacattacc agcaggtgag
    10141 tatattgtat gcaaaattga ggcagaatct tttgaagaac ttgttactac tgctttaaat
    10201 caagcaaata agtatctgtt tgaaacttgg cttccaaatc ataatttggt tacaaagcca
    10261 ttcatggcag aaaaatatta caaaggaaat gcagagatta attatatgga aatatggata
    10321 attcctgtgt aaacagtaaa tgctaaatag gaattatctg acgtaataaa aaggaaatag
    10381 aaagcttata aaggagggca tagtccgttg tgataaacat aaaagatata aattatgtac
    10441 ctaatattag tgaaataagc gtttatattg aaaactctgc atttgatgag ttgtatcagc
    10501 atatgaacaa tgaatataaa gcagtttgca aaatcgaata cagtaaagat gtctgggcac
    10561 gaggttggaa cgtaaagttt aaaaaatctg ggaaatcatt gtgtgttgtc tatccgaaga
    10621 agaactactt tactgtattg gtggttgtag gtaataaaga gaaagaagat gttgaaaact
    10681 tgttacctag gctttctgaa tatgtacagg aaatttatcg taacactaga gagggaaatg
    10741 gacaaaggtg gcttatgata gacttaaaat ctaaaaataa tgtatatcaa gatgtattaa
    10801 ggcttattga aattcgttat gccataaaat gtgtaaaacc gtaataaaaa tatttttcac
    10861 atacgtaatc tcaaggtatt atcgttgaga caagtaacct atataattat gggaaatgag
    10921 atttttagat acttaagaaa gtactttagg gggcttgcgt tatggaaaga tttaagtaca
    10981 attccacaca atcaaataca atctaataaa actttactaa aaattgaatg caatacagct
    11041 ttaaaggctc gtacaaacta tatgttttgt gcgggctttt ttcatttaat aggaatttgg
    11101 attcgtcaga gagtatatta taaaaataaa acgataaggg taccttaaaa ataaggtacc
    11161 tcaggctgta gacaaagtcc cggactctcg tctgggcttt tcttatattt gagttatcca
    11221 caattcaact ttttaagagt tatcttatta agaaaaaagt gtatgttttc caccctatag
    11281 ttttacttct gtgatatttg cagatgccac tcaagtagaa agtggtggta cggcagaaga
    11341 tgtcatgcag agttcagaaa gtctgggact accgcctaat tccttagaca cggaaagctc
    11401 aatcaagcag gggtgtaagt attttgcgtc cctgctttct tcctgcaaaa atcaaggtat
    11461 cgacgatttg aatgtagcga tacaatctta caactatggc gggggttatg tgggctatgt
    11521 ggcaggaaaa gggaaaaagc acacttttaa tcttgcagag agcttcgccc gtgagaaatc
    11581 gggtggaaag aaagtaacct acgccaaccc gatagccgtt gcaaagaacg ggggctggcg
    11641 gtatggctat ggaaatatgt tttatgtgga attagtcaat cagtatttaa ctgttccgca
    11701 ggtgtcgggg gaactggcac aaaaggtaat gaatgaagcg ttgaagtatc aagggtggaa
    11761 atatgtgttt gggggaagca atcccaacac ttcctttgat tgtagcggac ttgtgcaatg
    11821 gtgctatgga aaagctggta tctacttacc gagaacggca caaacacagt atgacgcaac
    11881 ccagcatatc cctttatcgc aggcaaaagc tggggagttg ttctttttcc attcaaccta
    11941 taacgctggt tcgtatgtaa c
//
LOCUS       DAMJVG010000101        11887 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.105, whole genome shotgun sequence.
ACCESSION   DAMJVG010000101 DAMJVG010000000
VERSION     DAMJVG010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11887)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11887)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11887
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.105"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            238..1278
                     /locus_tag="PC512_003237"
     CDS             238..1278
                     /locus_tag="PC512_003237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2442959.1"
                     /translation="MDKHSDSVMYGGMEVYNIWGTTTVDSIIGESDVMRALKNRICKI
                     GNSDSTVAITGESGTGKELIARAIHLAGNRGNKTFVAINCAAIPEPLLESELFGYTKG
                     AFSGADSKGKIGKFELANGGVVFLDEIGDMPIQLQSKLLRVLQEKKFTRIGSNELIDI
                     DVRIISATNRDLFELVKENKFREDLYYRLNVIPLEVPPLRERGDDIQILINNFIDKYS
                     RKMKKNVYHIEPDVEQMLLKYPWPGNIRELENTIELALNLLEEDGIIHKGIINRKILE
                     YFKLNNINIKLLEESDYEISMEQDILTLEEFERAYIKKVLKFYGNDTKSKKLAAKKLG
                     ISLATLYRKIDV"
     gene            1634..2956
                     /locus_tag="PC512_003238"
     CDS             1634..2956
                     /locus_tag="PC512_003238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HDF2442960.1"
                     /translation="MFDIDGRPPILKCLPLSMQHILAMIVGTVTVPIVVGGAVGVSPT
                     QITLLVQYALIIAGISTLIQLYPIGNIGSRLPIIFGVGFTYVPTLVAVGGNYGLASIL
                     GAQLIGGVATVLIGIFIKKIRKFFPNIVAGTVVFTIGLSLYPIAINYMAGGVNSPTYA
                     SMQNWAVAAITLVVVIGLSQFAKGYAKLAAIFLGIIVGYCVSLVLGIINFDPIREATW
                     FAIPKPLEFGMEFDMPVIISVVIVSIINAVQAIGDLSATTMGGMDRNITDKELSSGVI
                     GSGICTMIGALFGGLPPSSYSQNVGMVAMNKVISRFVLGIAGIFMLLSGFVPKFGALM
                     TTIPYSVLGGATISIFSIITMTGIKLIITEELSSRNITIVGLAIALGMGITSVPAAQE
                     AFPSFVKLVFGESPIVIATLVAFVLNLIIPNKSLEDEAKERAVMEETN"
     gene            3253..4614
                     /locus_tag="PC512_003239"
     CDS             3253..4614
                     /locus_tag="PC512_003239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine/pyrimidine permease"
                     /protein_id="HDF2442961.1"
                     /translation="MKTRNTSKYDVDGIPPLKESIPLALQHLLAMIVGNMVPAILIAN
                     VVGLNQGQATMLIQGSMLAAGLATFLQLYPIPLFKGFKLGSRLPVMMGMSYVFLGACL
                     SVAAKDGLAALFGAQIAAGVIVFFVGFGVKKIRHIFTPIVSGTIIACMGLGLFATAIK
                     NLAGGEGTQTFGSPINFTVGVIVAFVIIMINKYGKGLVKNSSILIGILVGYAISLVLG
                     LVDFSAVQGAAIVSLPTPAAFGLEFRPELIVMFTIIYIIGIADMMGACTIATVGAMDR
                     EVTDEELASVVLGNSITSIISSLFAALPTGVFSQNTAIVSMNKVTSRFVIALGALVLL
                     LAGISPALGAIMTTIPSCVVGGATLVVFSSIAMSGFSIMSMDGFTEENNLIAGVSIAT
                     SMGLTTAPQVLDQFPETIGTVLGGSSIVSGAIIAILLQTLFKLKSRKSAENVTSNLEE
                     NIG"
     gene            4687..6081
                     /locus_tag="PC512_003240"
     CDS             4687..6081
                     /locus_tag="PC512_003240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2442962.1"
                     /translation="MIDILIKNAIIVTVNKDRDVIFDGAIAIQGDRILDIGNTVDIEP
                     KYLDAKKVIDANGKVIFPGFINTHNHLFQVLLKGLGDDMALHEWLNTMMFPSAKFLTE
                     QDTYDAAMLGCMEGLKSGITTMVDYMHTHNRPGLTDGIVKAYKDLGIRGVVGRGCIDL
                     GIHKELIEDVETVEKDLRRVFEKYHNSENGRIKICVAPSSMWAISEEMGKMLWNIVKE
                     YDSYFTVHISETEFARTATKDIHGEIDIKLLEKWGIVGPEVVAVHCVCITDEDMEMLK
                     KYDIKVSHNVASNMYLASGVAPVPEMLKKGINVSLGLDGAASNNAQDMVELMKLTALQ
                     HKVNNCDPLAISAEKVLEMATIEGARTLRMEDEIGSLEIGKKADLVIFNSMLSPKSIP
                     LHNPVSTLVYSASMHNVESVLVDGNVILENGKVTTIESEEQVLLNAQHAAEELCKRAN
                     VTNRMEGHKWNSLY"
     gene            6143..6613
                     /locus_tag="PC512_003241"
     CDS             6143..6613
                     /locus_tag="PC512_003241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="HDF2442963.1"
                     /translation="MEKIKLNINDYMYEIEVEKNETLLHVLREKLNLTGAKQGCNSGS
                     CGACKVLIDGVDMKSCKLLAKNCEGKVIYTIESFANGENLHPIQEAFIEVGAVQCGYC
                     TPGMIITTQALLNRNASPNEDEIREAFKENLCRCTGYVKIIEAVKLSAARLGGR"
     gene            6616..8832
                     /locus_tag="PC512_003242"
     CDS             6616..8832
                     /locus_tag="PC512_003242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HDF2442964.1"
                     /translation="MEKVIGKSYPLKDAALKVTGQMKYVADMKPQNVLYAKMLLSPVA
                     HAKIKSIDTSEAEKVVGVRAIATYLNTSQRKYNGSLRFYEHKIPENEVIFSDTVRFVG
                     DRVAAVAAETPEIAEKAVKLIKVEYEELPAVFTIQDAIKEDAICIHGDSNIVSQNNIN
                     GGDVEKGFKECDYIFEDEYSTPAIHHSAIETHSVIAHYDYNDKLTVHTPCQNTFGFRI
                     ILSQIFGMSLNKVRVIRPAIGGSFGGKLELTIEPVAAALSKMTRRPVKMVLTRKESMI
                     STRTRHGSFVKLKTGVNKDGEVIAQDIKIYTNTGAYASSALNVIGALSHKVFKVYKIP
                     NIKFTGMPVYTNTPIAGAMRGYGSPQIFMAQQAQFAKIAKEIGMDLVDFQNKNAVEPD
                     DVDIIFHGSLGNPRVLDCIEQGKKMFKWDEKKKLPKEEGKYLRGIGMAIGAHGNGVFG
                     AHRDVVTLTLKLNEDGTLTLLTGAHDMGNGVVTMQTMMVAEVLGITPDKVDTFETDTD
                     ACTFNLGDYASRGVFVEGGGAKKTAEKLKNLILEEAEKLLETSKEDLYLDNGCVISKL
                     DENVKASLSDVAVYSQSKSLRELTVVEDYSSPAGRTSYGVHFAEVLVDKETKDIKVVD
                     FVAVHDVGRVINPLNLEGQLEGGIHMGLGYALSEELAFDEQGRPKATDFKTYKLFRTV
                     DMPKCQVAFVDGYEKAGPFGGKSIGECAVVPVAPAVANAVYNATDVEIHSLPIKLK"
     gene            8915..9586
                     /locus_tag="PC512_003243"
     CDS             8915..9586
                     /locus_tag="PC512_003243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF2442965.1"
                     /translation="MAKILGICGSPRKGATEYAVLEALKEAETIPGIETEYWSVRGKK
                     ISPCVHCDACIRKETMCIIKDDIQELEQKILEADGIIVGSPVYDMNITAQLTAVFNRL
                     RPMYLVHPGKLQNKVGAAITTGGTRYGGQELTKLPIINFFLMHEMLVSGGLGGCYIGG
                     TIWSKDGKAKGAQEDETGMDTVKRLGKGAAEAVMVSKFGLEKWNVVKEELDVKKDEKS
                     PLRDH"
     gene            9949..11163
                     /gene="dpaL"
                     /locus_tag="PC512_003244"
     CDS             9949..11163
                     /gene="dpaL"
                     /locus_tag="PC512_003244"
                     /EC_number="4.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HDF2442966.1"
                     /translation="MLKEIKWKVNNLPKGDKENCIKFLNEEEITKVRNFHKSFPQYKE
                     TPLANLEGLAKKLGVAGVYVKDESYRFGLNAFKVLGGSYSMGRYLAQRLDTDISELGY
                     DKLTSKEIKEKLGEITFFTATDGNHGRGVAWTANKLGQKSVVLMPKGSSEFRLNKIKG
                     EGADASITDLNYDDAVRLANDYAEADDHGVMVQDTAWDGYEEIPAWIMQGYGTMAQEA
                     IEQLKEYGVDRPTHVFVQAGVGSLAGAVQGYVASIYDECPITVVVEADEADCYYKSAE
                     AGDGKPRFVGGDMPTIMAGLACGEPNTIGFEVLKNHAAAFVSAPDWVSAKGMRTLGNP
                     LNGDEKVISGESGAVTTGLLVAAMEREDLADLRKDLKLDENSRILLISTEGDTDPDKY
                     RSIVWDGEYPSI"
     gene            11290..>11887
                     /locus_tag="PC512_003245"
     CDS             11290..>11887
                     /locus_tag="PC512_003245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HDF2442967.1"
                     /translation="MLNEQRKQEVTEICQKLIQNPSSSGNEEGVVKAIEESFEKLGFD
                     SWSRDRYGNIVGCIKGNKPGKKILFDGHIDTVPVPDASKWSVPPFEGKIVDGKIYGRG
                     TSDMKGQYTAMMSAVAYFAKDTNRDFAGELYVAGVVHEEIFEGVSAREISKAVQPDYV
                     VIGESSELNLKIGQRGRGEIVVETFGKPAHSANPEKGVN"
BASE COUNT         4496 a         1367 c         2405 g         3619 t
ORIGIN      
        1 aaattttaaa aattatttcc atataaaata tggcattgta attgcttatt taatagagca
       61 tttttgtaaa atgaagaaag tatatctatc aaattaaaac taagtagata tactttttat
      121 taagttttgt tttaaaataa tattattaaa ttataactaa gcttttctgt tatgatataa
      181 ttaaatagat aatgtgaatg attattatat agaatactta tttggagttg atattttatg
      241 gacaaacaca gtgattcagt aatgtatggt ggaatggaag tatataatat ttggggaaca
      301 acaacagtag actccataat tggagagtct gatgtaatgc gtgctcttaa gaatagaatt
      361 tgtaaaattg gaaatagtga ttctactgta gctataactg gagaaagtgg cactggaaaa
      421 gaattaatag caagagccat tcatctcgca ggaaacagag ggaataaaac attcgttgct
      481 ataaactgtg ctgctatacc agaaccttta ctagaaagtg aactttttgg atatacaaaa
      541 ggagctttta gtggagcaga ttcaaaaggt aaaattggta agtttgaatt ggccaatgga
      601 ggggttgtat ttttagatga gataggagat atgccaattc aactacaatc aaagttattg
      661 agggtattac aggaaaagaa gtttacgaga ataggttcaa atgaactaat tgatatagat
      721 gttagaatca tatcagctac taatagagat ttatttgagt tggttaagga aaataaattt
      781 agagaagact tatactatag attgaatgta atacctttag aagtgcctcc acttagagaa
      841 agaggagacg atatacaaat attaataaac aattttatag acaaatattc gagaaagatg
      901 aagaaaaacg tgtaccatat agagccagat gtggaacaaa tgttgcttaa gtatccttgg
      961 ccaggaaata ttagagagtt ggaaaatact atagaactgg cattaaacct tcttgaggaa
     1021 gatggaataa tacataaagg aataataaat agaaagatac ttgaatattt taagttaaat
     1081 aatataaata taaagttact tgaggaaagt gactatgaga taagtatgga acaagacata
     1141 cttacacttg aagagtttga aagagcctat ataaagaaag tgttaaagtt ttacggaaat
     1201 gatactaagt ctaaaaaact ggctgccaaa aaacttggaa tatcactagc tacattgtac
     1261 agaaaaatag atgtataata attaggcttt ttattctcaa ttctaaaatt tgaaattata
     1321 aaattgataa aaaacacttg gaaaactatt ttctaagtgt ttttttgtgt aatagcattt
     1381 tattatccaa aaataaaaaa aatttaaaag aatttaaaaa aataaatgct ttaataaatt
     1441 atcaaatact aacaaatata ataaaaatta tatatgtaaa acaattatgt taaaaaattg
     1501 gcattataat tgcttcatat taagttgaga tgacaaaata aaaaaagaaa ggatgttgtg
     1561 tgagataata ataactgtca ttaaaaaata gttgggagtg ataaccttga gtaaatatca
     1621 aaagaatgtt tctatgtttg atattgatgg aaggccacca attttaaagt gtttgccact
     1681 atcaatgcaa catatactag caatgatagt tggaactgtt acagtaccta tagtcgtagg
     1741 aggagctgtg ggtgttagcc ctacacaaat aacactttta gtgcaatatg cattaataat
     1801 agctggtata tcaacactta tacaactata tccaatagga aatattggtt caagattgcc
     1861 tataattttt ggagttggtt ttacttatgt accaacactt gtagcagtcg gaggaaatta
     1921 tggattagca agcattttgg gtgcacaatt aataggggga gtggctacag tattaatagg
     1981 gatattcata aaaaagataa gaaaattttt tccgaatata gttgcaggaa cagtggtttt
     2041 tacaattgga ttatctttgt atcctatagc aataaattat atggcaggtg gtgtaaatag
     2101 tcctacttat gcctctatgc aaaactgggc agtagcggct ataacattag tggtagttat
     2161 aggtcttagt caatttgcaa aaggatatgc aaaattggca gcaatatttt tgggaattat
     2221 agttggatat tgtgtatctt tagttctggg tataataaat tttgacccta ttagagaggc
     2281 aacttggttt gcgataccta aaccgcttga atttgggatg gaatttgata tgcctgtaat
     2341 aatctcagta gtaattgtaa gtataatcaa tgctgttcaa gcaattggag acttatcagc
     2401 tactacaatg ggaggcatgg ataggaatat cacagataag gaattatcaa gtggagtaat
     2461 aggaagtgga atttgtacta tgataggagc tttgtttgga ggtttaccac catcatcata
     2521 tagccaaaac gtggggatgg tagctatgaa caaagtaata agtagatttg tgcttggaat
     2581 agctggtata tttatgttat tgtcggggtt tgtgcctaaa tttggtgcat taatgactac
     2641 tataccatat tctgttttag gaggagctac aatatctata tttagtataa taacaatgac
     2701 aggtataaag ttaattatta cagaagagtt gtcatcaaga aatattacca ttgttggttt
     2761 ggcaattgcc ttaggcatgg gaataacatc agtcccagca gcccaagagg catttccttc
     2821 atttgtaaag ttagtatttg gagaatctcc aatagtaatt gcaacattgg ttgcattcgt
     2881 tttaaatcta ataataccaa ataaaagtct agaggatgag gctaaagaaa gagctgttat
     2941 ggaagagact aattaagata taataattta aaagaattgt ttaaattatt tagtatgaga
     3001 ttgttagatt atttttgata gctattcatt ttaataaaaa atttaacaaa taaatatata
     3061 ccaggcaatt aatgttcatt taagttgaaa atcggggagg caatatttag aaatttgtta
     3121 attttttata aaaatagctc agtttagctg tgtttatcgg ttgagcaata aattcatggt
     3181 cataaaaata tttatagaaa ataattataa aaatatttag tcaagatatt tatgtatggg
     3241 aggatttatt ttatgaaaac acgtaatact tcaaaatatg atgtcgatgg gataccacca
     3301 ctaaaggaat caataccttt ggccttacaa catctgttag caatgatagt aggaaatatg
     3361 gtacctgcga tattaatagc aaacgtggta ggacttaacc aggggcaagc aacaatgttg
     3421 attcagggtt ctatgttagc agcaggttta gcaacgtttt tacagttata tccaatacct
     3481 ttatttaaag gatttaagtt aggttcaaga ttacctgtaa tgatgggaat gagttatgta
     3541 tttttaggag cttgtctttc agtagcagct aaagatggtt tagcagctct atttggagca
     3601 cagattgctg ctggggtaat cgtattcttt gtaggatttg gagttaagaa aattagacat
     3661 atattcactc caatagtttc tggaactata atagcatgta tgggacttgg actattcgca
     3721 acagctataa agaatttagc tggaggagaa ggcacacaaa catttggaag cccaataaac
     3781 ttcacagtag gagttatagt tgcttttgta ataataatga taaataaata cggtaaaggt
     3841 ttagtaaaaa attcttcaat attaatagga atattagtag gttatgctat atctttagtt
     3901 ttaggattgg ttgatttctc agccgttcaa ggagcagcta tagtatcttt accaacacca
     3961 gcagcttttg gattagaatt tagaccagag ttaatagtaa tgtttactat tatttacata
     4021 ataggtatag ctgatatgat gggtgcctgt acaatagcta cagtaggagc aatggataga
     4081 gaggtaactg acgaagaatt agcatcagtt gtattaggaa attctataac ttctataatt
     4141 tcatcactat ttgcagctct tccaactgga gtatttagcc aaaatacagc aattgtatct
     4201 atgaacaaag ttacaagtag atttgtaata gcactagggg cacttgtatt attactagca
     4261 gggatatctc cagcattggg tgcaataatg acaactatac catcttgtgt tgttggtgga
     4321 gcaactttag tagttttctc atcaatagca atgtctggtt tctctattat gagtatggat
     4381 ggattcactg aagaaaacaa tcttatagca ggtgtatcta tagcaacaag tatgggtctt
     4441 acaactgctc cacaagtttt agaccaattc ccagaaacaa ttggaactgt ccttggaggg
     4501 tcaagtatag tttctggagc aataatagct atattacttc aaacattatt taaattaaag
     4561 tcacgtaaaa gtgctgaaaa cgttacttca aatcttgaag aaaatattgg ataaatgtat
     4621 tagatataat atgagaaaac catatggtaa aatgttgtaa tgaaagtatt caaaggggga
     4681 tttaagatga ttgatatact aataaaaaat gcaataattg ttacagttaa taaagacaga
     4741 gatgttatat ttgatggagc aatagctatt caaggtgaca gaatcttgga cataggaaat
     4801 acagttgata tcgagcctaa gtatcttgat gctaaaaaag ttatagatgc taatggaaaa
     4861 gtaatattcc ctggctttat aaatactcat aatcacctgt tccaagtgtt attaaaaggt
     4921 ttaggtgatg atatggcact tcatgagtgg ttaaatacaa tgatgtttcc atcagcaaaa
     4981 ttcttaacag aacaagatac ttatgatgct gcaatgcttg gatgtatgga aggtttaaaa
     5041 agtggtataa ctacaatggt tgattatatg catactcaca atagaccagg acttacagat
     5101 ggaatagtaa aggcatataa agatttaggc ataagagggg ttgtaggtag aggttgtata
     5161 gatttaggta ttcacaaaga gcttatagaa gatgtggaaa cggttgaaaa agatttgaga
     5221 agggtattcg aaaaatatca taattcagaa aatggaagaa taaaaatctg tgtagctcct
     5281 tcttcaatgt gggctatatc tgaagaaatg ggtaagatgc tttggaatat agttaaagaa
     5341 tatgattcat attttacagt tcatatatct gaaacagaat ttgcaagaac agcaacaaag
     5401 gatatacatg gagaaataga tataaaatta cttgaaaaat ggggtatagt aggtccagaa
     5461 gttgtagcag tacattgtgt atgtataact gatgaagaca tggaaatgct taaaaagtat
     5521 gacataaaag tttctcataa tgtagcaagt aatatgtatc ttgcttctgg tgttgcacct
     5581 gtgccagaaa tgttaaaaaa aggtataaat gtgagtttag gtcttgacgg tgcagcaagt
     5641 aataacgcac aagatatggt agagcttatg aaactaacag ctttacaaca caaagtaaat
     5701 aattgtgacc ctctggcaat ttctgcagag aaagttcttg aaatggctac aattgaggga
     5761 gcaagaactc ttagaatgga agatgaaata ggttctttgg agattgggaa aaaagctgac
     5821 ctagtaatat ttaactcaat gctttctcca aaatcaatac ctcttcacaa tcctgtatca
     5881 actttggtat actcagctag tatgcacaat gtagagagtg ttttagttga tggaaatgta
     5941 atacttgaaa atggaaaagt aactacaatt gaaagtgaag aacaagtgtt gcttaatgca
     6001 caacatgcag cagaagaatt atgtaagaga gctaatgtaa ctaatagaat ggaaggacat
     6061 aagtggaata gcttatacta atattaaaat aagattgtaa taatattcta ttacaacatt
     6121 agtttatctg taggaggaga aaatggaaaa aataaaatta aatattaatg attacatgta
     6181 tgaaatagaa gttgaaaaga atgaaactct tttgcatgta cttcgtgaaa aattaaatct
     6241 aactggagcg aaacaaggtt gtaatagtgg cagttgtgga gcatgtaaag ttttgataga
     6301 tggagttgac atgaaatctt gtaaacttct tgcaaaaaac tgcgaaggta aagttatata
     6361 cactatagaa agttttgcta atggagaaaa tcttcatcca atacaagaag cttttataga
     6421 agttggagct gtacaatgtg gatattgtac tcctggtatg attataacaa cacaagctct
     6481 tttaaataga aatgcatctc ctaatgaaga tgaaattaga gaagctttta aagaaaatct
     6541 ctgtagatgc acaggatatg taaagattat agaagctgta aaattatctg cagctagatt
     6601 agggggtaga taattatgga aaaggtaata ggaaaatcat accctctaaa agatgcagct
     6661 ttaaaagtta ctggtcaaat gaaatacgtg gctgatatga aaccacaaaa tgtactttac
     6721 gctaagatgc ttttaagccc tgtagcacat gcaaaaataa aaagtataga tacaagtgaa
     6781 gctgagaaag tagtaggtgt tagagctata gctacttatc tcaatacatc acaaagaaaa
     6841 tacaatggtt cattaagatt ttatgagcac aaaatacctg aaaatgaagt tatattttca
     6901 gatacagtta gatttgttgg tgaccgtgtt gcagcagtag ctgcagagac tccagaaata
     6961 gcagagaaag ctgtaaaact tataaaagtt gaatatgaag aattgccagc tgtatttact
     7021 atacaagatg caataaaaga agatgctatc tgcatacatg gagattcaaa tatagtttct
     7081 caaaacaaca taaatggggg agatgtagaa aaaggcttca aggaatgtga ctatatattt
     7141 gaagatgaat actctactcc agcaatacat catagtgcaa tagagactca tagtgtaatt
     7201 gcacactatg attataatga taaattaact gtacatacac cttgccaaaa tacatttgga
     7261 tttagaataa tactatctca aatttttggg atgtcattaa ataaagtaag agttataaga
     7321 cctgctattg gaggctcatt tggtggaaaa ttagaactta caattgaacc agtagcagcc
     7381 gcattatcaa aaatgacaag aagaccagtt aaaatggttc ttacaagaaa ggaatctatg
     7441 atatcaacaa gaactcgtca tgggtctttt gtaaaattaa aaactggtgt aaataaagat
     7501 ggtgaagtaa tagcacaaga cataaaaata tatacaaata caggagcata tgcatcaagt
     7561 gctttaaatg ttataggagc acttagtcat aaagtattta aagtttataa aataccaaat
     7621 ataaagttta ctgggatgcc tgtatataca aatacaccaa tagcaggagc tatgagaggc
     7681 tatgggtcac ctcaaatatt tatggctcaa caagctcaat ttgcgaaaat agcaaaggaa
     7741 ataggtatgg atttagtcga ttttcaaaat aaaaatgcag tagagccaga tgatgtcgat
     7801 ataatcttcc acggttctct tggaaatcct agagtattgg attgtataga gcaaggtaag
     7861 aagatgttta agtgggatga aaagaaaaaa cttccaaaag aagaaggaaa atatttaaga
     7921 ggtataggta tggcaatagg tgcacatggt aatggagttt ttggtgcaca tagagatgtt
     7981 gttacattga ctcttaaatt aaatgaagat ggtacgttga cactgctaac aggagctcat
     8041 gatatgggta atggtgttgt aactatgcaa acaatgatgg tagctgaagt tttaggaata
     8101 acacctgata aagttgatac atttgaaact gatacggatg catgtacatt caaccttggt
     8161 gactatgcaa gtagaggggt atttgtagaa ggtggaggag ctaaaaagac agcagagaaa
     8221 ttgaaaaatc ttatattaga agaagcagaa aaattacttg aaacatcaaa agaagattta
     8281 tatctagaca atggatgtgt aattagtaaa cttgatgaaa atgtaaaagc atcactttct
     8341 gatgtcgcag tatatagtca aagtaaatca ttaagagagt taactgttgt tgaagattat
     8401 tcttcaccag ctggacgtac ttcttatggt gtacattttg ctgaagtttt agtagataaa
     8461 gaaactaagg atataaaagt agttgatttt gtagctgtac atgatgttgg tagagttata
     8521 aatcctctaa atttagaagg acaattagaa ggtgggattc atatgggtct aggatacgca
     8581 ttgagtgaag aattggcatt tgatgaacaa ggtagaccta aagctactga ttttaaaaca
     8641 tataaattat ttagaactgt agatatgcca aaatgtcaag ttgcatttgt agatggttat
     8701 gaaaaagctg ggccttttgg tggtaagagt attggagaat gtgccgttgt accagttgcg
     8761 ccagctgttg caaatgcagt atataatgca actgatgtag agatacattc attaccaata
     8821 aaattaaaat agtataaatt aaagcagaaa taacaattta ttgtatttgt aaatagataa
     8881 taaaaataga tttatttggt gaggagatat tattatggca aagatattag gtatttgtgg
     8941 aagtccacgt aaaggagcaa cagaatatgc agtgttagaa gctttgaaag aagcagaaac
     9001 tatacctggt atagaaactg agtattggtc agttagaggg aaaaaaataa gtccttgtgt
     9061 acattgtgat gcatgtataa gaaaagaaac tatgtgtatt ataaaagatg atatccaaga
     9121 attagagcaa aaaatattgg aggcagatgg aattatagta ggttctccag tttatgatat
     9181 gaatataact gctcaactta cagcagtatt taatagactt cgtccaatgt atttagttca
     9241 tccaggaaaa cttcaaaata aggttggtgc agctataact actggtggaa ctagatatgg
     9301 tggccaagaa ttgacaaaac ttcctataat aaatttcttc ctaatgcatg aaatgttagt
     9361 gtctggaggt ttaggtggat gctatatagg tggtacaata tggagtaaag atggaaaagc
     9421 aaaaggtgcc caagaggatg agacaggtat ggacacagta aaaagacttg gaaaaggtgc
     9481 agcagaggca gttatggttt ctaagtttgg tcttgaaaaa tggaatgtcg taaaagaaga
     9541 attagatgtt aaaaaagatg aaaaatcacc tcttagagac cactaaagat ttattatatt
     9601 attgaatata tacaaatagt gatgtaatag attattgcat cactatttta tgttttaatt
     9661 tagattttat agattttata ttaaaaaata tagaaacaaa gtgttttgag atttattttt
     9721 aaattttaaa aatgagaatt aaaaagtgag aagatagaaa aggtttttta gttattaaat
     9781 tctacataca ttgtatgaac taaagataga aaagaaaaaa taataaaagc attgcaattt
     9841 ctatactaaa gagtcataga aaaatatcta gtatatattt agtgttggca tgttaattgc
     9901 ttatatatta aagtataaaa atttaacaat aatttggagg tattttagat gttaaaagaa
     9961 attaaatgga aagtaaataa tttgccaaag ggcgataagg aaaattgtat caaattttta
    10021 aatgaagaag aaataactaa ggttagaaat tttcacaaaa gctttcctca atataaagaa
    10081 actccattag caaacctaga aggtttagca aaaaaattag gtgttgcagg agtatatgta
    10141 aaagatgaat cttatagatt tggattaaat gcatttaaag tattaggtgg ttcttattct
    10201 atgggtagat acttagctca aagattagat acagatatat ctgagttagg gtatgacaaa
    10261 ttaacttcaa aagaaataaa agaaaaatta ggagaaataa ctttctttac agctacagat
    10321 ggaaatcacg gtagaggagt tgcttggaca gctaataaat taggtcaaaa atctgttgta
    10381 ttaatgccaa aaggttcttc tgaatttaga ttaaataaaa ttaaaggaga aggtgcagat
    10441 gctagtataa cagacttaaa ctatgatgat gcagtaagat tagctaatga ttatgcagaa
    10501 gctgatgacc atggagtaat ggttcaagat acagcatggg acggatatga agaaatacca
    10561 gcgtggataa tgcaaggata tggaactatg gctcaagaag ctatagagca attaaaagaa
    10621 tatggagtag atagaccaac acacgtattt gttcaagcag gagttggttc acttgctggt
    10681 gcagttcaag ggtatgttgc ttcaatatat gatgaatgcc caataacagt agtagtagag
    10741 gctgatgaag ctgattgtta ctataaatca gcagaagctg gagatggaaa accaagattt
    10801 gttggaggag atatgccaac tataatggca gggcttgctt gtggagagcc aaatactata
    10861 ggatttgaag tattaaaaaa tcatgcagca gcatttgttt cagcaccaga ctgggtttct
    10921 gctaagggta tgagaacatt aggtaatcct ttaaatggtg atgaaaaggt aatttctgga
    10981 gaatctggag cagttacaac tggtctttta gtagcagcta tggaaagaga agatttagca
    11041 gatttaagaa aagatttaaa attagatgaa aattcaagaa tacttttaat aagcacagaa
    11101 ggagatactg accctgacaa atatagaagt atagtttggg atggagaata tccaagtata
    11161 taaggaatta ctaaaatgca attattagat attggtttac atatttagaa gatatataag
    11221 ttctaaaatt tagaaaatat ataagtatat aaaatacata cattataaaa aatctagggg
    11281 gataatgaaa tgttaaacga acaaagaaaa caagaagtaa ctgaaatatg ccaaaaatta
    11341 attcaaaatc ctagttcttc tggaaatgaa gaaggtgttg taaaagcaat agaagagtct
    11401 tttgaaaaat taggttttga tagttggtca agagatagat atggaaatat agtaggatgt
    11461 ataaaaggta acaagccagg taagaaaata ttatttgatg gacatataga tacagttcca
    11521 gttccagatg caagtaaatg gagtgttcct ccttttgaag gaaaaatagt tgatggaaag
    11581 atatatggta gaggaacttc tgacatgaaa ggtcaatata ctgcaatgat gtctgctgta
    11641 gcgtattttg ctaaagacac taatagagat tttgctggag aactatatgt agcaggtgtt
    11701 gttcatgaag aaatatttga aggtgtttcg gctagagaga taagtaaggc tgttcaacct
    11761 gactatgttg taataggtga gtcttcagag ttaaacttaa agattggtca gagaggtaga
    11821 ggagaaatag tagtagaaac ttttggtaaa ccagctcact ctgctaatcc agaaaaaggt
    11881 gtaaatg
//
LOCUS       DAMJVG010000102        11536 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.106, whole genome shotgun sequence.
ACCESSION   DAMJVG010000102 DAMJVG010000000
VERSION     DAMJVG010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11536)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11536)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11536
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.106"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            90..980
                     /locus_tag="PC512_003246"
     CDS             90..980
                     /locus_tag="PC512_003246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2442968.1"
                     /translation="MAKLTLEHIKGNTYYIPLPTIVGVYVDGKDAILIDSGNNKDTAR
                     QVLRLLEEHNLNPKLIINTHSNADHIGGNAYLKNQTKCKIATTKIEGYFTENPILESA
                     FLYGGYPSKALKNKFLLAKESEVDYIIPSNGKIVDTELEAISLPGHYFEMIGVRTPDN
                     VLFVADSLTPENIITKYHFFFLLDIDSQFKTLEKLRMLEADFFVPSHSVKTTDIKSLI
                     NINKKKMEEIIDNIKKVCYEPVMIDEVIEKMCDLYNVKLDANQYVLVGSTIRSYITYL
                     YENNMVEYIFDGGKMMIKAA"
     gene            1198..2952
                     /locus_tag="PC512_003247"
     CDS             1198..2952
                     /locus_tag="PC512_003247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp23"
                     /protein_id="HDF2442969.1"
                     /translation="MYIMNKKFKKFSKKLSILILVLTMFLFNNLTANAQIKEDSIIGI
                     DRYETAGLIADRQTYDTVILVNGDKNLSDGLSSSGLAGAINAPILLTKKSEIPKATLN
                     RLDNKSLNVVKKVYIIGGYNTIENSVEKDIKRKGIQVERINGNNRIETSYNVAKKINE
                     VSSVKEVMLTNGFVGEADAMSIAPVVAKNKGAIILTDGKSVPFKTEGLNVYAIGGKSA
                     INEDLVNETKAIRIGGNDRFETNKKVMEKFYNGATDFYITNGYQLVDALTLSPLAKEK
                     PIVLVADGSNKGILKGAKSITKVGGIDANIYKQCLDMIKYNNMDMTPNILKHLTSVEG
                     NEVSEILIESDNLGVVVEKTNTNKFEFDYVSVTNEKNCTFSVYKENSSNNIKNGKLVV
                     SAKKKIDKKDSDLQDMNGDNMINANKDRMVNVIKIGVPDKMYSNFKVDVESGSVELYN
                     IKGGATVDVNDGIANIVDNNVTNPFNINTNSGISGVTAETISSEIKFRANNGIVNVTA
                     TNINGNISLFGSDNKDTFDGIFKLNLKKEPSNLHLKLIGNGINKLPEGWSKDYILGNG
                     QPIIEVKNNGINNISIGE"
     gene            3336..4322
                     /locus_tag="PC512_003248"
     CDS             3336..4322
                     /locus_tag="PC512_003248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDF2442970.1"
                     /translation="MKKITINDIANLAGVSKSTVSRYLNNKDISDSTKEKIKTIIDEY
                     GYEPNAFAQSLRAKKTYFIGIITPCLDSFVKSKIMMAIDEELKKLKYTSLIINTNRKI
                     RSEIDSISKLASLKVDGIILIGTEITKEHKNEIEKLDIPIVVVGQKVDGINSIVNDDY
                     GAGYKMGQYIANKGYKNIVYLGVDESDISVGLNRKNGVLNGLKDKGYDAKVFYTDFDQ
                     EMSIQRSGEMLESENPDIIICATDNIAIATMKEINKRGKSIPQDISVAGFGGYDVLSI
                     ISPKLTTIKFENKNAGKVAANTIVNLIQERKEPLLKEIKFELIEGESTINKN"
     gene            4491..4639
                     /locus_tag="PC512_003249"
                     /pseudo
     CDS             4491..4639
                     /locus_tag="PC512_003249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423822.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIB"
     gene            4658..6139
                     /locus_tag="PC512_003250"
     CDS             4658..6139
                     /locus_tag="PC512_003250"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HDF2442971.1"
                     /translation="MYKEPKYRTILESTKEELNKLRNISLNDKYKPLFHIHPQHGLLN
                     DPNGLAYYNGKYHVFYQWYPYDATHGMKHWAYVSSDDFVNWNREDVALIPIESYESHG
                     AYSGNAIEVDGKLHMYYTGNIKYSAEDRYAYQNLAIMNKDGKITKYENNPIVSEIPKG
                     YTGHVRDPKVFKRKDKYFMLLGAQTSDKKGVIIVYESKNSIDWNFKGELNVKNIDEDF
                     GYMWECPDYINIDEKDILIFSPQGVEPKGFDYQNIYNVVYAIGNMDLDNLTFEIDTMK
                     ELEKGFDFYAPQTFIKDSQIILFAWAGMGEVLYPTDKNKWAHCLTVPRKLNIKNNKLL
                     QMPVDELIKLRYDETSGQNTIKNNINIIENDENVYELNINIKNIDSNKFGLELFSSQD
                     EGVKLEFNKLGNIVTLDRSNFKKVFGVEYGTNRKEYINIDENTNIKVLADRSILEIFI
                     NEGEVVFTSRIFAKENSNQIRVYSDKIVEYEYTKFKLKQGIEL"
     gene            6165..7136
                     /locus_tag="PC512_003251"
     CDS             6165..7136
                     /locus_tag="PC512_003251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase"
                     /protein_id="HDF2442972.1"
                     /translation="MKKVISIGEALIDFIPNQNGGKLKNVSEFRRVAGGAPANVSAVV
                     AKLGGKSSFISKLGKDAFGDYIIDVLNEVNVNTDYVLRTSKANTGLAFVSLKEDGNRD
                     FSFYRNPSADMLLEADEVKKEWFNNCHILHFCSVDLIDSPMKLAHKKAIEYALESNSI
                     ISFDPNIRLPLWDSEQSCKKAISEFLPFAHIVKISDEELEFITGENDIEKSLHKLFVG
                     NVELVLYTKGKDGVDAYTKKVKGMCKGVKVNAIDTTGAGDSYIGSFLYTLLYKQITLN
                     DIKEMKQETLNEYLEFSNYYAARSTTIKGAISSYATKEEITEFIKNL"
     gene            complement(7392..7994)
                     /locus_tag="PC512_003252"
     CDS             complement(7392..7994)
                     /locus_tag="PC512_003252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF2442973.1"
                     /translation="MEVCILMGSPKKKGNTAAILKPFIEELENYNSNIEVIWLYDCKI
                     EPCIACKKCQDNLFDFGCYCKDDVQKIFKKILMCDLIVFATPIYSWYCTSPMKALLDR
                     LVYGMNKYYGNEKGPALWAGKSVALITTCGYRPEKGADIWENGMKRYCKHSQLKYIGM
                     LVERDLGKPNFMNKEKEEHSRQFAKQIYYILSNSIELDNC"
     gene            8275..9486
                     /locus_tag="PC512_003253"
     CDS             8275..9486
                     /locus_tag="PC512_003253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="HDF2442974.1"
                     /translation="MYSNEDYKFIEENAPCYIYDETNIIEKCKELKNNILGFDFLYSI
                     KTNPYNKIVKSIAEQGFGADASSTNEVMISSKCGVSKDDIYYSSPGKTEIDIETVLDK
                     CIIIADSITEIELINKISKKHNQKVKIGIRINPDFTMDDDSAKSSKFGIDIEDMSSVF
                     KMLSMCDYVSVVGIHIHIKSQVLDFEKLGHYYEKCFFIALNLNKSKYINIEFINFGSG
                     LGVAYDNLRENPLNLKELSKLTQKIAFTNSNTLKSRLLIESGRFIVCKSGNYYVKIVD
                     IKVSRGKKYLIVKNGLNGFMRPIISNLIENITCGVELEGQEPLYTSNHAFSLSVLNNL
                     KEEEYVNVVGNLCTSLDVIANNVKLKKANIGDLISISNAGSYSYSLSPLLFSSYEFPK
                     QYYKRKDGYIE"
     gene            9554..9751
                     /locus_tag="PC512_003254"
     CDS             9554..9751
                     /locus_tag="PC512_003254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter"
                     /protein_id="HDF2442975.1"
                     /translation="MELWKRNLFVCWIGMFFSSIGMSQIAPILPLYIKQLGVTDVSLI
                     QQYSGIIFGCTFVVAAFFSPI"
     gene            9785..10756
                     /locus_tag="PC512_003255"
     CDS             9785..10756
                     /locus_tag="PC512_003255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2442976.1"
                     /translation="MLLRASIGMGIVIFTMAFVQNVYQLLGLRILQGVFTGYATACTT
                     LIATQTDKNHSGWALGTLATASTTGSLIGPTVGGYIESILGLKSTFIITGGLLFVSFI
                     ISILFVVDNFKPKEIKESISIPKEQLNILPNKFLIASIFVTTFITQLALYSIEPIVTI
                     YISQLTNFASNVALIAGLTFSASGLANLLAAQKLGKMSDKIGPQKVLLISLLWAGIIF
                     IPQAFVKTAWQLMLLRFLLGLSVAGLNPSVNSLLKKIAPEEYVGKIFGYNASAQYIGC
                     SSGAFLGGQISAHLGIRTVFFSTSLLLFRNALWMYKFTGLFIKDKTK"
     gene            10943..11320
                     /locus_tag="PC512_003256"
     CDS             10943..11320
                     /locus_tag="PC512_003256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2442977.1"
                     /translation="MTISKIPQAELKVMKFIWEKNDTVTSKETIEAMERKYGWKQTTT
                     LTLLSRLVKKHFLSAEKIDRYTHYTIVVGHKEYLSVETKDFLSNIHDNSLQSLISALH
                     DDEVVDKDMLDLFESHFKNLEEE"
BASE COUNT         4735 a         1154 c         1887 g         3760 t
ORIGIN      
        1 aaataaaaat atattataaa aacaatttga ttggaatttt cagaaaatta atgctataat
       61 taaaagtaaa tttaaaggga ggttataaaa tggctaaatt aactctagaa catataaaag
      121 gaaatacata ttatattcca ctccctacaa tagtaggtgt atacgtagat ggtaaggatg
      181 caattttaat tgacagtgga aataataagg atacagctag acaagtttta agattattag
      241 aagaacataa tttaaatcct aaattaataa taaacactca ttcaaatgca gaccatatag
      301 gaggaaatgc atatttgaag aatcaaacaa aatgcaagat tgctacgact aaaattgaag
      361 gatattttac agaaaatcca atattagaat cagcattttt atatggtggc tatccaagta
      421 aagcactgaa gaataaattt ttattagcaa aggaaagtga agttgattat attatacctt
      481 caaatggcaa aattgtagat acagaacttg aagcgatttc tcttccaggt cattattttg
      541 aaatgattgg tgttagaact ccagataatg ttttgtttgt tgcagatagt cttacaccag
      601 agaatataat tactaaatat cattttttct tcctactgga tatagattca cagtttaaga
      661 cactagaaaa attgagaatg ttagaggctg atttctttgt tccaagtcac tctgtcaaaa
      721 ctacagatat aaaaagttta attaatatta ataagaagaa gatggaagaa ataatagata
      781 atattaaaaa ggtttgttat gagccagtta tgattgatga agttattgaa aaaatgtgtg
      841 atttgtacaa tgtcaagctt gatgctaatc aatatgtgtt ggttggaagt acaatacgtt
      901 cttatataac ttatttatat gagaataata tggttgaata tatatttgat ggtggtaaga
      961 tgatgataaa agctgcgtaa atagtaataa ttttcaaatt atatgatgaa attgttttag
     1021 tatgactgtt atttgaaaag taatataaaa aaatttatat aaataagcta agatgattga
     1081 tataaagtta ctgataattt taaggtaata tatacgttac tataatatta tgttattatt
     1141 tgtaaataag gggataattt ataagcaaat taaagacctt aatttacagg aggaatagtg
     1201 tatattatga ataaaaaatt caaaaaattc agtaaaaaac taagtatatt aattttagtt
     1261 ttgactatgt ttctttttaa taatttaact gcaaatgcac agattaaaga agattcaata
     1321 ataggaattg atagatatga aacagcagga cttatagcgg atagacaaac ttatgatact
     1381 gtaatattag ttaatggaga taaaaattta tctgatgggc tttcatcaag tggattagct
     1441 ggagctatta acgcaccaat acttttgact aaaaaaagtg aaataccaaa agctacttta
     1501 aatagactag ataataagag tttaaatgtt gtaaaaaaag tatatataat tggtggttat
     1561 aatactattg aaaattcagt agaaaaagat ataaaaagaa aaggtattca agtggaaaga
     1621 ataaatggta acaatagaat tgaaactagt tataatgtag ctaaaaaaat aaatgaagta
     1681 agtagtgtaa aagaggtaat gcttacaaat ggatttgtag gagaggctga tgctatgagt
     1741 atagcacctg tagttgcaaa aaataaagga gctataatac ttacagatgg gaaatcagtt
     1801 ccatttaaga ctgaaggttt aaatgtttac gctataggtg gcaaatctgc gataaatgag
     1861 gatttagtaa atgaaactaa agcaattaga atcggaggaa atgatagatt tgagaccaat
     1921 aaaaaggtaa tggaaaagtt ttataatgga gctacagatt tttatataac aaatggatat
     1981 caattagtag atgcactaac attatctcct ttagccaaag aaaaaccaat cgttttagtt
     2041 gctgatggaa gtaataaagg tattttaaaa ggagctaaaa gtataacaaa agttggaggt
     2101 attgatgcca atatatataa acagtgttta gatatgatta aatataataa tatggatatg
     2161 actccaaata ttttaaaaca cttaacttca gttgaaggaa atgaagtttc tgaaatactt
     2221 atagaatcag ataatttagg tgtggttgtt gaaaagacga ataccaataa atttgagttt
     2281 gattacgtaa gtgtaactaa tgaaaaaaat tgtacttttt ctgtatataa agaaaattct
     2341 tctaataata taaaaaatgg aaagctagtt gtaagtgcta agaaaaaaat agataagaaa
     2401 gatagtgatt tgcaagatat gaatggcgac aatatgataa atgcaaataa agataggatg
     2461 gtaaatgtga taaaaattgg agttcccgat aaaatgtatt ctaattttaa agtagatgtt
     2521 gaaagtggtt cagtagaact ttataatatt aaaggaggag ctactgttga tgtcaatgac
     2581 ggaattgcta acattgttga taacaatgta acaaatcctt tcaatataaa tactaatagt
     2641 gggatttcag gtgtaacagc tgaaactata tcatctgaaa taaaatttag agcaaacaat
     2701 ggaattgtaa atgtaacagc tacaaatata aatggcaata taagtttatt tggaagcgat
     2761 aataaagata cttttgatgg aatatttaaa ttaaatctga aaaaagaacc atcaaattta
     2821 cacttgaagt taattggaaa tgggataaat aaattgccag aaggttggtc taaagattat
     2881 attttaggaa atggacaacc aattattgaa gttaaaaata atggcataaa taatatatca
     2941 attggagaat aaaaacatat gaaaataaag tttatatagt tttaaaaatt atagaatttt
     3001 aaaatattta tatatattct ttaaataaaa aattattttt taagtgataa ttaagtgttt
     3061 atcgataagg ctatggttgt aaaaatcata gccttatttt tatattataa ataaattaga
     3121 gtatttatca attcatagta gataaaattg aaattaaata taacaacaaa aaatgaaaat
     3181 tacaattaat ttaatgttaa agactcaatt atttggatgt ggaatggata gtacaagtag
     3241 tatataaaaa gtattgactg gacaaataac tatattttat tttaaatata taatataatg
     3301 taataaaata tatcaaatgt agaaggtgat aacctatgaa aaaaataaca ataaatgata
     3361 ttgctaactt ggcaggagta tctaaaagta ctgtatcaag atatctaaac aataaagata
     3421 tcagtgattc tactaaagag aaaataaaga caataataga tgaatatgga tatgagccga
     3481 atgcatttgc tcaaagtttg agagctaaaa aaacatattt tattggtatt ataacaccgt
     3541 gtttagattc ttttgtaaaa tctaaaatta tgatggcaat agatgaagaa ctcaaaaaat
     3601 taaaatatac atcactaatt attaatacta atagaaaaat aaggtcagaa atagatagta
     3661 tatcaaagtt agctagtcta aaagttgatg gaataatact aattggtacc gaaataacta
     3721 aagaacataa gaatgaaatt gaaaagttag atataccgat agttgtagtt ggacaaaaag
     3781 ttgatggtat caatagcata gtgaatgatg attatggagc aggctataaa atgggtcaat
     3841 atattgctaa taaaggttac aaaaacattg tatatttagg tgttgatgaa agtgatatat
     3901 cagttggttt aaatagaaaa aatggagtac ttaatgggtt aaaagataaa gggtatgatg
     3961 caaaagtatt ttatactgac tttgaccaag aaatgtctat acaaagaagt ggagaaatgc
     4021 tagaaagtga aaatccagat ataataatat gtgcaactga taatatagca atagcaacaa
     4081 tgaaagaaat caataagaga ggtaaaagta taccacaaga tatatctgta gctggatttg
     4141 ggggatatga tgtattgtct attataagcc ctaaacttac aacaataaag tttgaaaata
     4201 aaaatgcagg taaagtagca gcaaatacga tagtaaattt aatacaagaa agaaaagaac
     4261 cactattaaa ggagattaaa tttgaattaa tagaaggtga aagtacaata aataaaaatt
     4321 aagatacaca ttacatatat tagtaatgtg tattttttta ctaaaaaaac tataattcta
     4381 aaaattagga aaactttttt gaaagaaata ttgcatctga aataaattta tgctaatctt
     4441 taattaaacc ggtttcgaaa ccggtttaat taaaccgata gaatagcaaa atgagtgcaa
     4501 aaataactga ttgtaacaaa gtatcaaagt aattattgga gtacatagga ataaacaaaa
     4561 tataaaagat gtagcacatt gtgtaataag actaagaatt gttttagata gcaataataa
     4621 agcaaatata aaattataaa agaaaaggaa taaaaatatg tacaaagagc ctaaatatag
     4681 aaccatatta gaatcgacaa aagaagaatt aaataaatta agaaatatat ctttaaatga
     4741 taaatataaa ccactatttc atatacatcc acaacatgga ctacttaatg acccaaatgg
     4801 attagcatat tataatggta agtaccatgt attttatcaa tggtatccat atgatgcaac
     4861 tcatggaatg aagcattggg cttatgtaag ttctgatgat tttgtaaact ggaatagaga
     4921 agatgtagca ttaataccaa tcgaaagtta tgaatctcat ggagcatatt caggtaatgc
     4981 gatagaggta gatggaaaat tgcatatgta ttatacaggg aatataaaat atagtgcaga
     5041 agatagatat gcatatcaaa acttagctat aatgaacaag gatggtaaaa taactaaata
     5101 tgaaaataat ccaatagtaa gtgaaatacc aaaaggatat acaggacatg taagagaccc
     5161 aaaagtattt aaaagaaagg ataaatactt tatgttactt ggagcacaaa caagtgataa
     5221 aaaaggagtt ataatagtat atgaatctaa aaactctata gattggaatt ttaaaggaga
     5281 attaaatgta aaaaacatag atgaagattt tggttacatg tgggaatgtc cagattatat
     5341 taatatagat gaaaaagata tattaatatt ttcaccacaa ggagtagaac ctaaaggatt
     5401 tgattatcaa aatatatata atgtagtata tgctattggt aatatggatt tagataattt
     5461 aacatttgaa atagatacaa tgaaagaact ggaaaaagga tttgatttct atgctccaca
     5521 aacatttata aaggactcac aaataatact atttgcatgg gctggaatgg gagaagtttt
     5581 ataccctaca gataaaaaca aatgggcaca ttgtctaact gttccaagaa aattaaatat
     5641 aaaaaataat aagctattgc aaatgccagt agatgaatta attaaattaa gatatgatga
     5701 aacaagtggg caaaatacta taaagaataa tattaatatt atagaaaatg atgaaaatgt
     5761 atatgagctt aatattaata taaaaaatat tgacagcaat aaatttgggc tggaattatt
     5821 ttcatcacaa gatgaaggtg taaaattaga atttaacaaa ttaggaaaca ttgtaacttt
     5881 agacagaagc aactttaaaa aagttttcgg tgttgaatat ggaacaaata gaaaagaata
     5941 tataaatatt gatgaaaata ctaatatcaa agtactagcg gatagaagta ttttagaaat
     6001 ttttataaat gaaggagaag tagtatttac tagtagaata tttgctaaag aaaattctaa
     6061 tcaaataagg gtttatagtg ataaaatagt agagtatgag tatactaaat ttaaattaaa
     6121 gcaaggtatt gaattataaa aacacattat aaggggtaga aaagatgaaa aaagtaatta
     6181 gtataggaga agctttaata gactttatac ctaatcaaaa tggtggtaaa ttaaaaaatg
     6241 tatcagaatt tagaagagta gcaggaggag ctccagcaaa tgttagtgct gttgtagcaa
     6301 agcttggagg aaaatcgagt tttatatcta agttaggaaa agatgcattt ggtgattata
     6361 taatagatgt attaaatgaa gtaaatgtaa atactgatta tgtattgaga acaagtaaag
     6421 caaatacagg acttgctttt gtatcattaa aagaagatgg taatcgtgat ttctcatttt
     6481 atagaaatcc aagtgcagat atgcttttag aagctgatga agttaaaaaa gagtggttta
     6541 ataattgtca tatcctacat ttttgttcag tagatttaat agatagtcca atgaaattag
     6601 cacataaaaa agcaatagaa tacgcacttg aaagtaatag tataataagc tttgacccta
     6661 atataagatt acctttatgg gatagtgagc aatcttgtaa aaaggcaata tcagaatttt
     6721 taccttttgc tcatattgtt aagatatctg atgaagaatt agaatttata acaggagaaa
     6781 atgatataga aaaatcatta cataaactct ttgtggggaa tgttgaacta gtattatata
     6841 caaaaggaaa agatggagta gatgcataca ctaaaaaagt aaaaggtatg tgtaaagggg
     6901 ttaaagtaaa tgcaatagat acaaccggag caggagattc ttatataggt tcatttttat
     6961 acaccttatt gtataaacaa ataacattga atgatataaa agaaatgaaa caagaaacgt
     7021 taaatgagta tttagaattt tctaattatt atgcagctcg tagtacaact attaaaggtg
     7081 cgataagttc atatgcaaca aaggaagaaa taactgaatt tataaaaaat ttatagtagg
     7141 aatgagtaat aggttttgaa ggaagtaaca tgtaaagagt ttttaaggat gtttactatg
     7201 aaaataatta acatataaaa agcaataagg aggctgtctc aaaatagaga taagcctctt
     7261 tatcattgtt gaaatgataa aaaatatttt aattattgtt actttttaga agaatatata
     7321 tcttatttta aataagcaaa ttatgtaaga tttatttata ttatcaatac tttacttgga
     7381 gtattatgtc tttagcagtt atctaattca attgaattag ataaaatata ataaatttgt
     7441 tttgcaaatt gacgagaatg ttcttctttt tctttattca taaaattagg tttacctaaa
     7501 tcacgttcaa caagcattcc tatatatttt aactgtgaat gcttacagta gcgcttcata
     7561 ccattttccc aaatatcagc acccttttca ggtctatatc cacatgttgt aataagtgct
     7621 actgattttc ctgcccatag agcggggcct ttctcattac catagtattt attcattcca
     7681 tacaccaatc tgtcaagtag tgctttcatt ggagaagtgc agtaccaaga ataaattgga
     7741 gtagcaaaaa caattaaatc acacataaga attttcttga aaattttctg aacatcatct
     7801 ttacaataac atccaaaatc aaataagtta tcctgacact ttttacaagc aatacatggc
     7861 tctattttac aatcatataa ccatattact tcaatatttg aattataatt ttctaattcc
     7921 tcaataaaag gttttaaaat agcagcagta ttaccttttt tcttaggact tcccataaga
     7981 atgcatactt ccatattgat acctccacag tattttaaaa tagtttttag tgcttaatat
     8041 agttttagga tactatgaga atacgttaac aacaatacac tttgtatatt tgtaataaaa
     8101 ttgaaacaaa ttgttttatc aataaaagtt ggaatgtatc tataattaaa aatattttag
     8161 gtatgttttt acatatatgt gtgtagttaa ctatggtaat ttattgtaaa attatcttat
     8221 aggattataa ttgcttaatt tatgattata tttaaaatct tggaggtaaa aaatatgtac
     8281 tcaaatgaag actataaatt tatagaagaa aatgcaccat gttatatata tgatgagact
     8341 aatataattg aaaaatgtaa ggaattgaaa aataatattt taggttttga ttttttatat
     8401 tctataaaaa caaatccata taacaaaatt gtaaaaagca ttgcagagca aggttttgga
     8461 gcagatgctt cttcaactaa tgaagttatg atttcatcaa aatgtggagt ttctaaagat
     8521 gatatttatt attcatcacc aggcaaaaca gagattgata tagaaactgt tttagataaa
     8581 tgcataatta ttgcagatag tattacagaa atagaactta taaataagat atctaaaaag
     8641 cataatcaga aagttaaaat aggaataaga ataaatcctg attttactat ggatgatgat
     8701 agtgctaaat caagcaaatt tggtatagat atagaagata tgagcagtgt ttttaagatg
     8761 ttaagtatgt gtgattatgt atctgtagtt gggattcata tacatattaa atctcaggta
     8821 ttggattttg aaaagttagg acattattat gaaaaatgtt tttttatagc tttaaattta
     8881 aataaaagta agtatattaa tattgaattt ataaattttg gtagtggact tggagtagct
     8941 tatgataatc ttagagaaaa tccacttaat cttaaagagc tttcaaaatt aactcaaaag
     9001 attgctttta ctaattcaaa cacactaaaa tcaagacttc ttattgaatc aggacgtttc
     9061 atagtttgta aatcaggtaa ttattatgtt aaaattgtag atattaaagt atcaagaggg
     9121 aaaaaatatc ttattgtaaa aaatggactt aatggattta tgagacctat tatttctaat
     9181 ttaattgaaa atattacttg tggagtagaa ttagaaggtc aagagccatt atatacatca
     9241 aatcatgcct tttctctttc agtattaaat aatttaaaag aagaagagta tgtaaatgtt
     9301 gttgggaatc tctgtacatc attagatgta attgcaaata atgttaaatt gaaaaaagca
     9361 aacataggag atttgatttc aattagtaat gctggaagtt actcctattc tttatcaccg
     9421 ctattatttt caagttatga atttcctaaa caatattata aaagaaaaga tggatatatt
     9481 gagtaaacaa tagcataaat taataaactt agtattattg aaaaaattta aaatgcaggg
     9541 ggtgtaattc tatatggaat tgtggaaaag aaatttattt gtatgttgga taggtatgtt
     9601 ttttagttct atagggatga gccaaatagc acctatactt ccattatata ttaaacagtt
     9661 gggggtaact gatgttagtt taatacaaca gtattcaggt ataatttttg gatgtacctt
     9721 tgtagtagca gcattctttt cgccaatttg agggaaagct gctgataaat atggaagaaa
     9781 atcaatgctt ttacgtgcaa gtattgggat gggaatagtt atatttacca tggcgtttgt
     9841 tcaaaatgtt tatcagttat taggattaag aatacttcaa ggagttttta cgggttatgc
     9901 tactgcatgt actactctta ttgcaacaca gacagataaa aatcattcag gatgggcttt
     9961 gggtactctt gcaactgcat caactactgg ctcattaatt ggtccaacag taggaggata
    10021 tatagaatca atcttaggtc ttaaaagtac atttattata acaggaggat tgttgtttgt
    10081 atcatttatc atctctattt tatttgtagt agataatttt aaacctaaag aaataaaaga
    10141 atcaatttct atacctaaag aacaattaaa tatattgcca aataaatttt taattgcatc
    10201 tatttttgta accacattca ttactcaact agctttatac tctatagaac caattgtaac
    10261 catatatata tcacaactta caaattttgc atcaaatgta gctttaatag ctggattgac
    10321 attttctgca tcaggattag caaatttatt agcagctcaa aaacttggaa aaatgtcgga
    10381 taaaataggt cctcaaaaag tattgttaat ttcactttta tgggctggga ttatatttat
    10441 accacaagct tttgtaaaaa ctgcatggca actgatgttg ttgagatttt tattagggtt
    10501 gtcagttgca gggcttaatc cttctgttaa cagcttgctt aaaaaaattg caccagaaga
    10561 atatgtggga aaaatatttg gatataatgc atctgcccag tatataggct gttcatcagg
    10621 agcattttta gggggacaaa tatcagcaca tttaggtatt agaacagtat ttttttcaac
    10681 aagtttattg ttgtttagga atgcactttg gatgtataaa tttactggat tgtttattaa
    10741 agataagact aaataatcat actatttaca tttctaattt tatgatgtaa aataaatatt
    10801 ttttatgtaa tttatcatag aattatataa aaaataaccc tatggtaaaa attggaaaat
    10861 attattatcg acaaaatctt tgacttaaaa actatattgc gatagtatta atttaataaa
    10921 agtttgagag gggcgtaagg ttatgacaat ttcaaaaata ccacaagcag aattaaaagt
    10981 tatgaagttt atttgggaaa aaaatgatac agtaacatca aaagaaacta ttgaagctat
    11041 ggaacgaaaa tatggttgga aacaaacaac tacattgaca cttttatcaa gacttgttaa
    11101 aaaacatttt ttaagtgcag aaaaaataga tagatacact cattatacaa tagttgttgg
    11161 acataaggag tatttaagtg ttgagacaaa agatttttta agcaatatac acgacaattc
    11221 tttacagagt ttaatttcag cactacatga tgatgaagtt gttgataaag atatgttgga
    11281 tttatttgaa agtcatttta aaaatttaga agaagagtaa ttatatcagg atagaactct
    11341 aagaatttaa ttaatctatg gctgaaaacc ataaatggta ttatttaatc agctactcac
    11401 tattcataaa gtaatattaa ataggttctc taattagtaa aatgcctaaa ataattggaa
    11461 tagggagtat caagttaaat gataccactt atttaaataa gaaatgattt ttaaaattta
    11521 aaataatttt ataact
//
LOCUS       DAMJVG010000103        11469 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.107, whole genome shotgun sequence.
ACCESSION   DAMJVG010000103 DAMJVG010000000
VERSION     DAMJVG010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11469)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11469)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11469
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.107"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            46..867
                     /locus_tag="PC512_003257"
     CDS             46..867
                     /locus_tag="PC512_003257"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine kinase"
                     /protein_id="HDF2442978.1"
                     /translation="MQKKVAAINDLSGIGKCSLSVAIPILSALKVQCCPFPTAILSSQ
                     TGYPEFTFLDFTDEMVKYSNVWKNLKVNFDSIYSGFLGSKHQIEIVANFINDYPNAFI
                     VVDPVMGDNGVMYPIFTEEMRHEIKELVKHSDLTTPNLTEACFLTGNDYTKSDYNRDE
                     LIYIAKSVSDLGPSKVVITGILEDDNILNLAYDRDNDHVFFTSVKYNNCSYSGTGDIF
                     TSILCGMLVNKHDLGVAVNTATDFIYKTINYTSQFDTDRNDGVMFENFLSDLTNI"
     gene            complement(943..2331)
                     /locus_tag="PC512_003258"
     CDS             complement(943..2331)
                     /locus_tag="PC512_003258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase"
                     /protein_id="HDF2442979.1"
                     /translation="MLGGKKSNNKKVEKLRTIFIKYLSLFFIMTISIVLLLMLSFSVL
                     LSSGVILPANYAEKQFNKYKEQIISSEKVTEDIIPSIYEYGVYTLDGSLISGTFNKKE
                     SKEVWNLMRDIEERHAYSESYIKFFKKDEVFIIKYKIVSEYSSPILRAYLPKPETLGM
                     IIFSIIFFIEIVILSKVFGKKFNIEMELLKNTTEKIEQQDLDFVVESSKIYEINNVLF
                     SMDKMKLALKDSLEKQWMLEENRKEQISALAHDIKTPLTIIHGNTDLLIEINENPELL
                     EYMEYISKGVTQIEKYINTLIDISKTENGYILNKEAISMSEFIKDVLVQIEALASTKN
                     LDVEFYKQDNLPKNITIDRELLFRAIMNIISNAIDYSPSQSKLYISVSVRNKYLKFVV
                     TDCGSGFSKADLSKATEQFYTGDLSRNSKSHYGMGLYIVNNIVQKHNGILYIENSVKT
                     GGAMVTIEIPIV"
     gene            complement(2466..3224)
                     /locus_tag="PC512_003259"
     CDS             complement(2466..3224)
                     /locus_tag="PC512_003259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutG family
                     permease subunit"
                     /protein_id="HDF2442980.1"
                     /translation="MRQLIRIFCSDLIKLKRNFIILMHICIALMGMGLFLWYYKVSGA
                     DNILKIVAYLQVIAIAFPLLSGVVCSMFVEQEYYAGNYKHMLTTSNPKYLTLISKYII
                     LVCLGFVATLVSVLGFKFGISKAYFASSFYMISILILIGCNLFEYILHLFLSLRFGKG
                     TSIGVGIVEMLLSALLLTGLGSGIWQYFPCAWGVRFITIWSSFSSSKTVEYIKVESIK
                     AYQSTGLMCGFVTILAFVILCIWFSKWEGKKSEE"
     gene            complement(3226..3942)
                     /locus_tag="PC512_003260"
     CDS             complement(3226..3942)
                     /locus_tag="PC512_003260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="HDF2442981.1"
                     /translation="MERFIRVEFQKMKGTFGMKLIWIVPVFCILLCGLGGGQNAAFNW
                     WYTTFLPGALTLISSLIVLKDEKSKYRGILPLPIEMKDVWTGKMIYCIICCFIASIIS
                     AIGVVFVGIIYKETISIGQNIIATILIILLFMWQIPLCMFLASKFGIFVTVLINMFFT
                     IVGVAVFSTTEMWYMFPYSIPSRLMAVVLHILPNGLPVPEGSEFLNNAVILPGVLISI
                     VLFVLFALATRVWFNNREVK"
     gene            complement(3944..4651)
                     /locus_tag="PC512_003261"
     CDS             complement(3944..4651)
                     /locus_tag="PC512_003261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HDF2442982.1"
                     /translation="MSNYILQVKGVSKKFKEQMAVDNISLAIKSNSIYGLLGPNGAGK
                     STLLKMITGILNPTSGKIMFEGHRWTRKDLSNIGSLIESPAIYENLTARENLKVHTTL
                     LGLPDSRIEEVLETVDLRDTFKKRSGQFSLGMKQRLGIAIALLNHPKLLILDEPTNGL
                     DPIGIEELRELIRSFPKQGITVILSSHILSEVEQVVDEIGIISNGVMGYQGEVSKEQN
                     LEKLFMKVVAENRKRGQ"
     gene            complement(4767..5303)
                     /locus_tag="PC512_003262"
     CDS             complement(4767..5303)
                     /locus_tag="PC512_003262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDF2442983.1"
                     /translation="MNKIAVSFLIIATTLLSTACMDYSISAVELVDSKESAVVKKDED
                     AKEETTSKMINSKKTTKIPIEIISKDEKIVKYLQIDEESSLKDKLRLILDTLSNEYFN
                     GLDMEVEVKEKDNLVKINLIEPDKKSRVSWKDDYLNEQNIIYTINNIIKNVIQEEDNS
                     IWIEEVEIYYNGKLIELR"
     gene            complement(5405..6475)
                     /locus_tag="PC512_003263"
     CDS             complement(5405..6475)
                     /locus_tag="PC512_003263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HDF2442984.1"
                     /translation="MNKKLAIFAAVLLVIGIIGTTWSGILVMPSLINFGLEKEAEFKK
                     ENKLYQEKVNIDKLDIAVDNINVTIKKSSSEDVRVTTRGNNEFYKYNVTLKDKTLVVK
                     GERKYENKIKKIKNFDQLLNTSINSMFSHDYREIIIYVPNNVDINASSISSHLFVYDN
                     VASNTITYKTSYGGFSRAITENKVNRLENLNLISNNNLHLSTKSILGVKNVNIESESL
                     YISSENEDVFINNIEEYIPENVNIKEKIGRNSNYESEFYLYSDMPIAKFLDIEVPNSK
                     VRLDIPVNKYKFNCDIKSKEAIEEFNNDEEYDNDSYDYEHSEEHSNKYRNTREIKGLL
                     NKNLSNLEKEYTIKINSNSLEL"
     gene            complement(6468..7526)
                     /locus_tag="PC512_003264"
     CDS             complement(6468..7526)
                     /locus_tag="PC512_003264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HDF2442985.1"
                     /translation="MNLNKTEFLEILKDYLKKDFSESEVNDILRDYEEYFVDGLIEGK
                     SDMEIIASLGSPKSIAKELILQTKEKNIEEEKIINTDVLNDKFSKFKSDMKKGYSILK
                     DEAKEKYSKSKENIDGKIMNTDILNGKFSRFKSNVKKDYSILKDEAKEKYNKSKENIN
                     DKLTPSIEEGVGGLSRQVIKGLLVVLSLFLIVPAFAFVCAIVSATIALVCSLIAFVIL
                     IPFVIKFIAMVPDVMMFCIFATIAFVGLEILAWQILLFAIKLGKQLLNNYIHWIKRKN
                     IYIKANEKMEKRKKATLNDEDLNKDINEDSYNNDYYNREEESIKETDEYNDDSINFEA
                     IYKDLEDIENKKGEDKHE"
     gene            complement(7513..7845)
                     /locus_tag="PC512_003265"
     CDS             complement(7513..7845)
                     /locus_tag="PC512_003265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDF2442986.1"
                     /translation="MNTQFRKGVLEICVLALISKKDMYGYEIVHNISKVIDVNEGTIY
                     PILRRLTKDLYFETYILESNEGPARKYYRITSLGKENLSNLMEEWREFVKAVEILISE
                     DEGGNELE"
     gene            8044..9165
                     /locus_tag="PC512_003266"
     CDS             8044..9165
                     /locus_tag="PC512_003266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactosyldiacylglycerol synthase"
                     /protein_id="HDF2442987.1"
                     /translation="MKDDKTILILTAQFGAGHISAAKAVKECIIEKYSNYNVVIQNFI
                     NASIPMMNKPMVKLYENNTKYTPGLYNYYYYFKKSFDSRHDLSHKLYTPKLSEYIADI
                     NPDLIISTFPLAAACVNNFKIKNPDINIPTLTVITDVVDSMEWVFENTDLYFVPSPEI
                     KNRFFQKGINPDSIKVTGVPVDKRFQIESKELCCDKYRLLLLGGGRGLFDIDEDFMHW
                     IDEFIEEHSNSIEITIVTGKNKKLYDNLTHKKPLKNIKVLGFVNDMYNLIRECDLMLT
                     KPGGATIFEAIQSQTPVLVKMPKVGQEIENAKFIIDKGLGMIYSDDLDLKNIFYKLVS
                     NEFDSIINFMKKNLKEFKTVIHPEKIADYISELIDNHYS"
     gene            complement(9293..11191)
                     /locus_tag="PC512_003267"
     CDS             complement(9293..11191)
                     /locus_tag="PC512_003267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HDF2442988.1"
                     /translation="MDSLLYVIEKDKHTNEELREILKSNKNIRFVSLMGVDLGGNATD
                     EKIPVELFLEDIDKFLESAIQTDGSSVELYNIATLNNAKVDLMPDKSCHWYVDYNMEY
                     IDEEVGLPVGTLKIPAFLIHDNKKVCSRGVLQKADKYFKKSMYEIFREYPHVINNIGI
                     DSVDDIEEIMLTAATELEFWVNTPEDKADLEKLYVSQSLKEQYWKRTHGIIRTCLEKS
                     LIILQKLGVNPEMAHKEVGGIQSSISIDGRTNHAMEQLEVSWKFSTPLQAADNELLVR
                     DVIEDVFTSHGLEVTFKAKPIHGVAGSGGHTHVGVSAKLKDGSIKNLFAPKDLKEDYL
                     SELGYGALMGLLYNYEVLNPIVTASNDGFNRLVPGFEAPVCIVTSLGHSYEIPSRNRS
                     VLVGLIRDMKNPKTVRFELRSPSPLSNTYLVIAGCYQTMLDGIKAAAKSGLSTKELEK
                     ELSKNVGEESFYLEKDRAYRDENDVFEHYSLEERNARFGIPPATVYENMKNLEIYASK
                     LKSLKQGDVFTDSIIESFKIGAIDKWQKKLKTRIIEAGIQKIRSIVKIHTKENMDALD
                     EVVWNSISDLKFNIMKDTLTRESLFTRVREAIENKDYQTASDLQIELKRSMEEIQQLY
                     MQYKKNIY"
BASE COUNT         3844 a         1882 c         1250 g         4493 t
ORIGIN      
        1 attttggtat cattataatt aatacatact aatggagggt tttttatgca aaaaaaagtc
       61 gcagcaatta atgacttatc tggaatagga aaatgctcat tatcggttgc tatacctata
      121 ctttcagcat taaaggttca atgttgtcca tttccaacgg ccatactttc aagtcaaact
      181 ggttatcctg aatttacttt tttagacttt accgatgaaa tggtaaaata ttcaaatgtt
      241 tggaaaaatt taaaagtcaa ttttgatagt atatatagtg gttttttggg ttcaaagcat
      301 caaattgaga tagtggctaa ttttataaac gattatccca atgcttttat cgtagttgac
      361 cctgtgatgg gtgataatgg agttatgtat ccaatattca cagaagaaat gagacatgaa
      421 attaaagaat tagttaaaca ttcagattta actactccta atttaacaga agcttgtttc
      481 ttaactggaa atgattatac caaaagcgat tataatagag atgagcttat atatattgca
      541 aaatctgtat ctgatttggg acctagcaaa gtcgttatta ctggtatatt agaagatgat
      601 aatatattaa atttggctta cgatagagat aatgaccatg tattctttac atcagtcaaa
      661 tataataatt gttcttatag tggaactgga gatatattca catctatact ttgtggtatg
      721 ttagtaaata aacatgattt gggagtagcg gttaatactg caacagattt tatatataaa
      781 actataaatt acacatctca atttgatact gatagaaatg atggagttat gtttgaaaac
      841 tttttatcag atttaactaa tatataaagt caaaaaaact atccatttta taaataccta
      901 taaatcataa aatttaggta tttacaaaat ggatattatt tactaaacta ttggtatttc
      961 aattgttacc atagcaccac cagttttcac agaattttca atatataaaa tcccattatg
     1021 tttttgtaca atattattta caatatagag tcccattcca taatgagatt tagaatttct
     1081 actcaaatct cctgtataaa actgttctgt agcttttgac aaatctgctt tagaaaaacc
     1141 acttccacaa tctgtaacta caaattttaa gtatttatta cgtactgata cacttatgta
     1201 tagtttactc tggcttggtg aataatctat agcatttgaa attatattca taatagctct
     1261 gaataacagt tctctatcta tagttatatt tttaggcaaa ttatcttgtt tataaaactc
     1321 cacatctaag tttttagtac tagctaatgc ttctatttgc actaagacat cttttataaa
     1381 ctcactcata ctgattgctt ctttatttaa tatatagcca ttctctgttt ttgatatatc
     1441 tattaaagta ttaatatatt tttctatttg agtgacaccc tttgagatat attccatgta
     1501 ttctaataac tcaggatttt catttatttc aattaataag tcagtatttc catgtataat
     1561 tgttagtggt gtttttatat catgtgccag tgcagatatc tgttcctttc tattttcttc
     1621 tagcatccat tgtttttcta aagaatcttt taacgccaac ttcattttat ccatagaaaa
     1681 aaggacatta ttaatttcat aaattttact agattctaca acaaaatcta aatcctgttg
     1741 ttctattttt tctgtagtat tttttaaaag ctccatttca atattaaatt tcttgccaaa
     1801 tacttttgat aatataacaa tttcaataaa aaatattata ctaaaaataa tcatacccaa
     1861 tgtctctggt tttggtaaat atgctcttaa aattggagaa ctatactctg atactatttt
     1921 gtattttatt ataaaaactt catctttctt aaaaaacttt atataacttt ctgaatatgc
     1981 atgcctttct tcaatatctc tcattaaatt ccatacttct tttgattctt ttttattaaa
     2041 ggtccctgaa attaaactcc catccaaagt ataaacccca tactcatata tacttggaat
     2101 tatatcttca gttacttttt cacttgaaat aatctgttct ttatatttat taaattgttt
     2161 ttctgcataa ttagctggta aaattacacc tgatgataat aatacagaaa atgataacat
     2221 taaaaggagt acaattgaaa ttgtcataat aaagaataaa gataaatatt ttataaaaat
     2281 agttcttaac ttttcaactt ttttgttgtt agatttttta cctccaagca tttgtaccct
     2341 gtcctccaat agtttaatta attcataatt aatatctaac cagtttttta tttgattatt
     2401 ttatatcttt ttattgctaa gttatatttt aacataataa tataaataaa cagtcaattt
     2461 ttactctatt cttctgattt tttaccttcc catttagaaa accaaataca taaaattaca
     2521 aatgctaaaa ttgttacaaa accacacatt aaacctgttg attgatatgc ttttattgat
     2581 tcaaccttta tatattcaac cgttttagaa ctcgaaaaag acgaccaaat agttataaat
     2641 ctaacacccc atgcacaagg aaaatactgc caaataccag aacccaatcc agttaataat
     2701 aatgctgaaa gtaacatttc aactatacct actccaattg atgttccttt tccgaacctt
     2761 aaacttaaga ataaatgtaa tatgtattca aataaattac acccaattaa aattagaatt
     2821 gaaatcatat aaaagcttga tgcaaagtaa gccttagata taccaaattt aaaacctaat
     2881 acagacacta atgttgctac aaaaccaaga catactaaga ttatatattt acttataaga
     2941 gtaagatatt ttggattaga tgttgttaac atatgtttat aattccctgc ataatattct
     3001 tgttcaacaa acattgaaca cacaacacct gacaataaag gaaaagctat tgctataact
     3061 tgtaaatatg ctactatctt tagtatatta tcagctcctg aaaccttata ataccataaa
     3121 aacaatccca tccccattaa agcaatgcaa atgtgcatta gtattataaa atttctcttt
     3181 aattttatta aatcagaaca aaatattctt attaactgtc tcatattact tcacctctct
     3241 attattgaac caaacccttg tagctaaagc aaataataca aataaaacaa tagatattaa
     3301 tactcctggc aaaataacag cattatttaa aaattcactt ccctctggta caggaagacc
     3361 atttggcaga atatgcaata caacagccat taatcttgaa ggaatcgaat atggaaacat
     3421 ataccacatt tctgtagttg agaaaacagc aactccaaca atagtaaaga acatatttat
     3481 tagaactgta acaaatatac caaattttga agctaaaaac atacaaagag gaatctgcca
     3541 cataaatagt aaaataatta atatagttgc aatgatattt tgacctattg aaatagtttc
     3601 tttatagatt atcccaacaa aaactacacc tattgcagaa ataattgatg ctataaaaca
     3661 acaaataata cagtaaatca tttttccagt ccaaacgtct ttcatttcaa ttggcaatgg
     3721 taaaatacca cgatatttac ttttttcatc ttttaatact attaaagaag atattaatgt
     3781 taatgctcct ggaagaaatg tcgtatacca ccagttgaaa gcagcatttt gccctccacc
     3841 tagtccacat aaaagtatac aaaacactgg aactatccat atcaacttca ttccaaaagt
     3901 tcctttcatc ttttgaaatt ccactctaat aaatctttcc atattactgc cctctctttc
     3961 tattttcagc tacaactttc ataaaaagtt tttctaagtt ttgttctttt gatacttctc
     4021 cttgataacc cattactcca ttagaaatta ttcctatttc atctacaact tgttcaactt
     4081 cagacaagat atggcttgat aaaataactg taattccttg ttttggaaaa gaacgaatca
     4141 attctctaag ttcttcaata ccaatagggt caagaccatt tgtaggctca tctaagatta
     4201 aaagttttgg gtgatttaat aatgcaatag caataccaag gcgttgcttc atgcctagag
     4261 agaattgacc tgaacgcttt ttaaaggtat ctcttaaatc tacagtctct aaaacttctt
     4321 caatgcgaga gtcaggaaga ccaagtaaag tagtatggac ttttaaattt tctcgtgctg
     4381 ttaaattctc atatatagca ggagactcaa taagagaacc aatatttgat aaatcctttc
     4441 tagtccatct atgtccctca aacattattt ttcctgaagt tggatttaaa atcccagtta
     4501 tcatttttaa taaagtagat ttcccagctc catttggtcc taataatcca tatatagaat
     4561 tagatttaat tgctagtgaa atgttatcaa ctgccatctg ctccttaaat tttttagaaa
     4621 ctccttttac ctgcaaaata taattactca taattttcat cctttctttt gtcaaactta
     4681 tttacaagaa tcattctaaa tcataaatat aaggatttta taagaattaa aaaacaaaaa
     4741 aagatgtgtt aaaaacacat ctttttttat cttaattcta ttaattttcc attgtagtat
     4801 atctctactt cttcaatcca aatgctatta tcttcttctt ggatgacatt tttaataata
     4861 ttatttatag tatatattat attttgttca ttcaaataat catctttcca agaaactcta
     4921 ctttttttat ctggttctat caagtttatt ttaacaagat tatctttttc cttaacttct
     4981 acttccatgt ctaaaccatt aaaatactca tttgataatg tatctaagat taatcgcagt
     5041 ttatccttaa gtgaactttc ttcatcaatc tgtaagtact ttactatttt ctcatccttt
     5101 gaaattatct ctataggtat tttagtagtt tttttagaat taatcatttt actagttgtt
     5161 tcttcttttg catcttcatc cttctttaca actgctgatt ctttagaatc aactagctca
     5221 actgcactga tgctataatc catacatgcc gtactcaata aagtagtagc aattattaaa
     5281 aaacttactg ctattttatt cataagtatc cctctcctaa ttctctttcg atacttatta
     5341 taccatagta tagattatat ttttatactt ttaaatcaat ttataaatta ttatagtaaa
     5401 ttatttacaa ttctaagcta tttgaattta tttttatagt atattctttc tctaaattcg
     5461 acagattttt attcaaaagc ccttttattt ctctcgtatt tctatacttg ttgctatgtt
     5521 cttcactatg ttcataatca tatgaatcat tgtcatattc ttcatcatta ttaaattctt
     5581 caattgcttc ttttgacttt atatcacaat taaatttata cttatttact ggtatatcaa
     5641 gtcttacctt agaatttgga acttctatgt ccaggaactt agcaattggc atatcagagt
     5701 acaagtaaaa ttcactttca taatttgaat ttctacctat tttctctttt atatttacat
     5761 tttcaggtat atactcttct atattattga taaatacatc ttcattctct gaagatatat
     5821 acaatgactc tgattctatg tttacatttt taacgcctaa aattgatttt gttgacaagt
     5881 gaagattgtt attagatatt aagtttaggt tttctaatct atttactttg ttctctgtta
     5941 tagctctact aaaacctcca taagaagttt tatatgttat agtatttgaa gctacattat
     6001 cgtatacaaa taagtgtgag cttatacttg atgcatttat gtctacatta tttggtacat
     6061 atattataat ttctctataa tcatgtgaaa acatactatt tatagatgta tttaataatt
     6121 ggtcgaaatt tttaatcttt ttaattttat tttcatattt tctttcacct tttacaacta
     6181 aagtcttatc ttttaaagtt acattgtatt tgtaaaactc attatttcct cttgttgtta
     6241 cacgcacatc ttcacttgaa cttttcttta ttgtaacgtt tatattgtca acagctatat
     6301 ctaacttgtc aatatttact ttttcttgat aaagtttatt ttctttttta aattcagctt
     6361 ccttttctaa accaaagttt attaggcttg gcataactaa aatccctgac catgttgtcc
     6421 ctattatacc tattaccaat aaaaccgcag caaatatagc aagtttttta ttcatgttta
     6481 tcttctcctt tcttattttc tatatcttca aggtccttat atatcgcctc aaaatttata
     6541 ctatcatcat tatattcatc agtttctttt atgctttctt cttctctatt gtagtaatca
     6601 ttattatatg aatcttcatt aatgtcttta ttcaaatctt catcatttaa agtagctttt
     6661 tttctttttt ccatcttttc atttgctttt atataaatat tttttctctt tatccaatgt
     6721 atataattat ttagtaattg tttacctagt tttatggcaa ataataaaat ttgccatgca
     6781 agtatctcaa gccctacaaa tgctatggtt gcgaaaatac aaaacatcat aacatctgga
     6841 accattgcta taaatttaat cacaaatgga attaatataa caaaagcaat taatgagcat
     6901 actaatgcaa tagtagcaga tacaatagca catacaaacg caaatgctgg aacaattaga
     6961 aataaagata acactactaa taaccccttt ataacttgtc tggataatcc tcctacacct
     7021 tcttctatac ttggtgtaag tttatcattt atattttctt ttgatttatt gtacttttcc
     7081 ttagcttcat ctttcaagat agaataatcc ttttttacat ttgatttaaa tctactaaat
     7141 ttaccattta atatgtctgt attcattatt tttccatcta tattttcttt tgatttacta
     7201 tacttttctt ttgcttcatc ttttaagata gagtaacctt ttttcatatc tgatttaaat
     7261 ttactaaact tatcattcaa aacatctgta tttattattt tttcctcttc aatatttttt
     7321 tctttagttt gtaagataag ttcttttgct atagattttg gtgagccaag tgatgctatt
     7381 atctccatat cactctttcc ctctataaga ccatctacaa aatactcttc ataatctctc
     7441 aatatatcat taacttcgct ctcagaaaaa tcttttttta gataatcctt taaaatttca
     7501 agaaactcag ttttattcaa gttcattacc tccctcatct tcacttatta aaatctcaac
     7561 agcctttaca aattctctcc actcttccat cagattggat aaattctctt ttcctagtga
     7621 agttattcta tagtattttc tagcaggacc ttcattagat tctagtatat atgtttcgaa
     7681 atacaaatct tttgtaagtc ttcttagaat aggatatatt gttccttcat ttacatctat
     7741 tactttagag atgttatgta ctatctcata tccatacata tctttcttag atatgagagc
     7801 aagtacacaa atttctaaaa caccctttct aaattgtgtg ttcatatact ccatcctttc
     7861 tttaaataca cagtattgtg ttttacaagg tactatgtta aaacttctta tatcctcata
     7921 ataacacagt actatgttct gcacaatagt tatttttaaa tattcttgtt gattaaatcc
     7981 ttctataaat gtataatact ctaatcagat atattttatg aaagtggtga taaattggct
     8041 aaaatgaaag atgataaaac aatattaatc ctaactgctc aatttggtgc tggacatata
     8101 agtgctgcaa aagcagtcaa agaatgtatt attgaaaaat atagtaacta taatgttgtt
     8161 atacaaaact ttataaatgc aagtattccc atgatgaata agcctatggt aaaactttat
     8221 gaaaacaata caaaatatac tcctggatta tataattact attattactt taagaaatcg
     8281 tttgattcaa gacatgattt atctcataaa ttatatacac ctaaactttc tgagtatatt
     8341 gctgatataa atccagattt gattatctct acatttccac tagctgctgc ttgtgtaaat
     8401 aactttaaga taaaaaatcc tgatataaat atacctacac ttacagttat aacagatgtt
     8461 gtagatagta tggaatgggt ttttgaaaat acagatttgt attttgttcc ttctcctgaa
     8521 ataaaaaata gattttttca gaaaggaata aatcctgact ccataaaggt tactggagtt
     8581 cctgttgata agagatttca aattgaaagt aaagaactat gttgtgataa atatagacta
     8641 ttacttctag gtggaggaag aggtctattt gatatagatg aggattttat gcattggata
     8701 gatgaattta ttgaagaaca tagtaattct atagaaatta caatagttac tggtaaaaac
     8761 aaaaaattat atgacaatct aactcataaa aaacctctaa aaaatattaa agtacttgga
     8821 tttgtaaacg acatgtataa tctaataaga gaatgtgacc taatgctaac taagcctgga
     8881 ggagcaacta tatttgaagc tattcaatca caaactccag tactcgtaaa aatgccaaaa
     8941 gttggacaag aaattgaaaa cgctaaattt ataatagata agggtcttgg catgatttat
     9001 agtgatgacc tagaccttaa aaacatattt tataaattag tatcaaatga atttgattct
     9061 ataataaact ttatgaaaaa aaatttaaaa gaatttaaaa cagtcattca tccagagaaa
     9121 attgctgatt atatatcaga attaatagat aatcattaca gttaaattgt actattaaaa
     9181 aatttcaaac ataaaattaa aggcaatcaa gtatgatttt acacttgaga atttactcat
     9241 agtgtttaat aatacttgat tgcctttatc atatcaaaat caaattgtta tattagtata
     9301 tatttttctt gtactgcata tacagttgtt gtatttcttc catacttctc tttaattcta
     9361 tttgtaaatc tgaagcagtc tggtaatcct tattttctat agcttctctc actctagtga
     9421 atagtgattc tctagttaaa gtatccttca taatattgaa ctttaaatcc gatattgagt
     9481 tccaaactac ctcatcaagc gcatccatat tttcttttgt gtgtatcttg acaatacttc
     9541 ttattttttg aatcccagcc tctattattc tagtttttaa tttcttttgc cacttatcta
     9601 tagctccaat cttaaatgat tctattatac tatcagtaaa tacatcacct tgttttaaag
     9661 attttaattt tgaagcatat atttctaagt ttttcatatt ttcataaact gtagctggtg
     9721 gtattccaaa tcttgcattt ctttcttcca aactataatg ttcaaataca tcattttcat
     9781 ctctatatgc tctatctttt tctaaataga aactttcttc acctacattt ttagataact
     9841 ctttttcaag ttcttttgta ctaagaccac tcttagctgc tgcttttata ccatccaaca
     9901 ttgtttgata acatcctgct attactaaat acgtgttaga tagagggctt ggtgacctta
     9961 attcaaatct tacagtcttt ggatttttca tatctcttat taatccaaca agcactgacc
    10021 tatttcttga tggaatctca taactatgcc ctaaagatgt aactatacat acaggagctt
    10081 caaatccagg aactaatcta ttaaatccat cattagaagc tgttacaatt gggtttaata
    10141 cttcataatt gtaaagaagt cccataagag ccccatatcc tagttcactt agataatctt
    10201 cttttaaatc ttttggagca aatagatttt ttatacttcc atcctttaac ttcgcactta
    10261 ctcctacatg tgtatgtcca ccacttcctg ctactccatg aattggtttt gctttaaatg
    10321 taacttctag tccatgtgat gtaaatacat cctctataac atctcttact aataattcat
    10381 tgtctgctgc ttgtaatggt gtagaaaact tccaagaaac ctctaattgc tccatagcat
    10441 ggtttgttct tccatctata ctaatagaac tttgtattcc tccgacctct ttgtgagcca
    10501 tttcagggtt tacacctagc ttttgaagta taattaaact tttctctaaa caagttctta
    10561 taataccatg agttcttttc cagtattgct cttttaggct ttgtgataca tataatttct
    10621 ctaagtcagc tttatcctca ggagtattaa cccagaactc aagttctgta gctgctgtta
    10681 acattatttc ctctatatca tctactgaat ctattcctat gttatttatt acatgtggat
    10741 attctctaaa tatttcatac attgactttt taaagtactt atctgctttt tgaagtactc
    10801 ctctagaaca tactttttta ttatcatgta ttaaaaatgc aggtatcttt aatgttccaa
    10861 caggtagacc tacttcttcg tctatatatt ccatattgta atctacatac caatgacaac
    10921 ttttatctgg cattaaatct actttcgcat tatttaatgt agctatatta taaagctcaa
    10981 cacttgaacc atcagtctgt atagctgatt ccaaaaattt atctatatcc tccaaaaata
    11041 attctacagg aatcttttca tctgttgcat ttcctcctaa atcaaccccc attaaggaaa
    11101 caaatcttat atttttattg ctttttagga tttctcttaa ttcttcatta gtgtgtttat
    11161 ctttctctat tacgtataat agactatcca tttttccact ctcccataat ttttatgtat
    11221 attttatttt gttaaataca agataaattt cattttcctt acatttatga atttttcttg
    11281 caaattattc gtgttttatt cgtgttttta tttatattat tatatatcaa gtataaaaag
    11341 ttcgcaatat tttttattgg aaaaaatatt atacatacaa tagtttaaca tttttacaaa
    11401 tatggggtat actaaaataa aagtattttt atttgaaaat ttaattttat ttataatata
    11461 atctatagt
//
LOCUS       DAMJVG010000104        11173 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.109, whole genome shotgun sequence.
ACCESSION   DAMJVG010000104 DAMJVG010000000
VERSION     DAMJVG010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11173
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.109"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(14..646)
                     /locus_tag="PC512_003268"
     CDS             complement(14..646)
                     /locus_tag="PC512_003268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CatB-related O-acetyltransferase"
                     /protein_id="HDF2442989.1"
                     /translation="MTIPSSNKVYPRSNDYQTVYLKNVITRENIEVGDYTIYNDFYND
                     PRDFEKNNVLYHYPINNDKLIIGKFCSIACNAKFLMTSGNHSMKSKSTYTFPIFYEEW
                     KLDINHITDAWDNKGNIIIGNDVWIGYDSIIMSGVNIGDGAIIGTRAVVTNDVPPYSI
                     VGGVPAKIIKKRFNNDTISKLLEIKWWDWPYKKIQSNIKHIQSGNIDKLV"
     gene            complement(718..1071)
                     /locus_tag="PC512_003269"
     CDS             complement(718..1071)
                     /locus_tag="PC512_003269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase DNA-binding domain-containing protein"
                     /protein_id="HDF2442990.1"
                     /translation="MSTEKRRDNKDRILRTGESQRKDGRYAYKYVYSFGKPQFVYSWK
                     LVPTDKPPKGKRDDISLRDKEKAIQNDLDDSIDTIGKKMTVCQLYAKKNGLRKNIRLN
                     TKKGRHYLMKILNKE"
     gene            complement(1149..1352)
                     /locus_tag="PC512_003270"
     CDS             complement(1149..1352)
                     /locus_tag="PC512_003270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HDF2442991.1"
                     /translation="MNNTDVPIWEKYTLTIEEASKYFRIGEKKLRKLADENLDSGWVI
                     MNSNRIQIKRKQFEKIVDTLDFI"
     gene            complement(1742..1972)
                     /locus_tag="PC512_003271"
     CDS             complement(1742..1972)
                     /locus_tag="PC512_003271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2442992.1"
                     /translation="MKPTKEVLPFTIILLAVHGDVNAINGILKHFEHYIIRLSQKTLF
                     DEYGNPYIHVEEETKRMLGTKLITAILRFNLS"
     gene            complement(1974..2381)
                     /locus_tag="PC512_003272"
     CDS             complement(1974..2381)
                     /locus_tag="PC512_003272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF2442993.1"
                     /translation="MVDEKTIEHQFDSFCKTVLRNYARDIYDENKRRNDYLVSLESLS
                     LAELSKLSILDDYDSNYICMVSYDYNIRIEDVLMAQAIGKLTKRKQDIILLSFFLNMT
                     NADIATLMDLAENTIHYHKTNALKELKELMEEH"
     gene            complement(2741..3190)
                     /locus_tag="PC512_003273"
     CDS             complement(2741..3190)
                     /locus_tag="PC512_003273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2442994.1"
                     /translation="MELIEWNYAYITDLVEFANDKEIAKNLRDNFPHPYREQNARDFV
                     SFCLATPDVKQLSYAIFYQERAIGSISLTFEEDTSINKNAELGYWLARNYWGKGIATN
                     AVKEICKIAFEKYNLNKIHANVYSYNRGSSKVLEKCGFKIEEYCHNS"
     gene            complement(3204..4130)
                     /locus_tag="PC512_003274"
     CDS             complement(3204..4130)
                     /locus_tag="PC512_003274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442995.1"
                     /translation="MSDILSRITNKIGDKNIVDKLSALSKSDLNSLLLEVFDRQANTL
                     TATDILKSYQLNRFTIPSGIDPEEIHALESKLLRKAFNMDIKTIMLSPSAPLGSCSVF
                     GSVDQYNVVSALRGTETLADPSNMLAIIIADKLKRKEENNTIPIHMATTARVIRAQNF
                     VGKGLYSHFGLYCMVSSGIDTGSYTCEKMLLEKHLNYYKDILSEIENVRFSIILRKRN
                     GYKDNDGFFDRMVETIKLIFPNIELSIHNDDVDNNYYKGINFKLSVKQGNETVEIVDG
                     GFVDWTYQMLGNKKERCLISGIGLERFLVAVS"
     gene            4358..4585
                     /locus_tag="PC512_003275"
     CDS             4358..4585
                     /locus_tag="PC512_003275"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2442996.1"
                     /translation="MIVACNALTQLLYSWLATVFSNASIYWGASNSIFLTPRGNLPKR
                     SCINGASTDCLKKDKKSIVSNSSLRPILVQA"
     gene            complement(4809..5429)
                     /locus_tag="PC512_003276"
     CDS             complement(4809..5429)
                     /locus_tag="PC512_003276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HDF2442997.1"
                     /translation="MHLIDFMNEDIKKKLVKKTYKKKETILFAEQENEYVILMIDGIA
                     EAFILNVKGNISTIHLYRSGSFFGEMEQFNDGKKPVEIVAFTDCNVYKLHRDDFLNWL
                     RGDFEATKFLIREISSKLVVNAELIEELSSLSVKERLLRCISLHYYRSELNLLTKKQL
                     ASEVNAPIRSINRAINECVQEHLIAYENKRFSVINQREVLKNLPTT"
     gene            complement(5528..6796)
                     /locus_tag="PC512_003277"
                     /pseudo
     CDS             complement(5528..6796)
                     /locus_tag="PC512_003277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331151.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            6888..7703
                     /locus_tag="PC512_003278"
     CDS             6888..7703
                     /locus_tag="PC512_003278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage integrase family protein"
                     /protein_id="HDF2442998.1"
                     /translation="MVKLSDAKSWAIRMSEDGCAYKSIDNYKRSLKASFFMAIQDDCI
                     RKNPFNFQLSDVLEDTTEPKIALTPEQEMGLLSFMESDKTYCKYYDDVVILLETGLRI
                     SELCGLTLELDMKNKAIMVDHQLLSDTKIGYYVEVPKTTQGKREIPMTERAYQSFERI
                     VERRKNAKAEPIIVDGYQNFLFLKQDGLPKQATHYQSMLRALVKKYNKTHEDKLPKIT
                     PHTFRHTLCTNMANKGMSPNILQYIMGHKNITMTLGYYAHGSFSSSRAEMERL"
     gene            8375..9142
                     /locus_tag="PC512_003279"
     CDS             8375..9142
                     /locus_tag="PC512_003279"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HDF2442999.1"
                     /translation="MKRKVQVKNITIGEGRPKICVPIIGKNKKDIIKEAKELKDACLD
                     IIEWRVDFFENVENIKEVKEVLYELRSYIHDIPLLFTFRSVVEGGEKLISRDYYTTLN
                     KEISNTGLVDLIDVELFMGDEVIDEVVNFAHKKEVKVIISNHDFNKTPKKEEIVSRLC
                     RMQELGADLPKIAVMPQNEKDVLVLLEATNEMFKIYADRPIITMSMSGMGVISRLCGE
                     IFGSALTFGAAKSVSAPGQISFKELNSVLNLLHKSIN"
     gene            complement(9470..10147)
                     /locus_tag="PC512_003280"
     CDS             complement(9470..10147)
                     /locus_tag="PC512_003280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443000.1"
                     /translation="MIVIEGSDKFKIAKEYIDVEYTLFSKVTFRYEKLKFKDNAELEK
                     IKMFKYKNGYIPNKLNLSFGYGFSSYKKQIIRETVDTLRLTEIFSSENIEDIKFIKDG
                     TKKLEISIEKVVKFKRRKKRNYVCCYCPDMYRDIKLDKESINKIYNRKIKIEREVNIF
                     EDEDVIINKKVLKFPKSWTKNMQKYWLSENKYPIHSTVIDDDRYKCCNVQYTKNRVII
                     LYYIYNH"
     gene            complement(10297..10614)
                     /locus_tag="PC512_003281"
     CDS             complement(10297..10614)
                     /locus_tag="PC512_003281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2443001.1"
                     /translation="MNYIGKRLKEERKKANLTSKEFANMVGVSPWYITQIESGKKNPS
                     LKTFIKFVNILNISADVLIKDITSTGKTYLENDINEELKDLNSRELNLISQIIDIIKK
                     NKI"
     gene            complement(10636..10974)
                     /locus_tag="PC512_003282"
     CDS             complement(10636..10974)
                     /locus_tag="PC512_003282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2443002.1"
                     /translation="MANIGKIIGDRIKVYRTKLGYSQEFLAEKAGLHPTYIGQIERAE
                     TNTSINIIMKIATALDIPLELLFANIITTEGVDNSVPLECYEMINKLTEKEQIAMLEL
                     IKCIIKYKEI"
BASE COUNT         3690 a         1779 c         1615 g         4089 t
ORIGIN      
        1 aaattataaa atattaaact aatttatcaa tatttcctga ttgaatatgc ttaatgtttg
       61 attgaatttt tttatatggc caatcccacc atttaatttc taataatttt gaaattgtat
      121 cattattaaa tctctttttt ataatttttg caggtactcc tccaacaata gaatacggtg
      181 gaacgtcatt agtaactact gctcttgttc caataattgc accatcacca atatttacac
      241 ctgacataat tatagaatca taacctatcc acacatcatt tccaattata atgttaccct
      301 tattgtccca agcgtccgtt atatggttga tatcgagttt ccattcttca taaaagatgg
      361 gaaaagtata tgtggatttt gatttcattg agtgatttcc actagtcatt agaaattttg
      421 cattacatgc tattgagcaa aacttaccaa ttattaattt atcattgttt atagggtaat
      481 gatacaatac attgtttttc tcaaaatctc ttgggtcatt ataaaagtca ttatatattg
      541 tgtaatctcc aacttctata ttttcccttg ttattacatt tttaagatat acagtttgat
      601 aatcattact tcttggatat accttatttg aacttggaat agtcatattt aaatctctcc
      661 tttaatatat attatgtttt tgactattcc actactacaa tacatctctt cacagaatca
      721 ctccttgtta agaatcttca taagataatg gcgtcctttt ttagtgttaa gtcggatatt
      781 ctttcttagt ccattctttt tagcgtataa ctgacaaact gtcattttct taccaatagt
      841 gtcaatgcta tcatcaaggt cattttgtat tgctttttcc ttatccctta atgatatatc
      901 atcacgtttt ccctttgggg gtttatcagt aggtacaagt ttccaagagt aaacaaattg
      961 tggtttacca aatgaatata catacttata tgcgtatctt ccatcttttc tctggctctc
     1021 tccagttctt aaaattctat ctttattatc tcgtcttttt tcagttgaca tgataagaag
     1081 ctcctctcaa taaccgaatt gagcttgata cgtcatatga atattataac atataaggct
     1141 caatttcatt agataaagtc aagtgtatca acgattttct caaattgttt tctctttatt
     1201 tgaatgcgat tgctattcat aatgacccag ccagaatcaa ggttttcatc agcaagttta
     1261 cgtaattttt tctctccaat acgaaagtat tttgacgctt cttcaatcgt caaggtatat
     1321 ttttcccaaa taggtacatc agtattgttc atagaatgta tcactccttt ctatgttcgt
     1381 agttcagaag tagatagatg gctttggtaa gctccattgg tattttaacc aatcccattc
     1441 ttatgggcag aaccgtgtca tacaggtgta tcattatact gtggtacagg ttacggcaaa
     1501 acaaccgttc caaaggttat tcacaaatca ctatatagta gctctcttga ttaaggtcat
     1561 ggcgtatagt atttgttggc tatctgtatc acaaacgtat ctatctactt tattcagttg
     1621 tcaaagaaca gtcggcattg atttgtctat aaaaaatcac aatagcttat gggcttttat
     1681 agacaaataa ttagtgattc tccatgtacc aaatagcttg atacatggag agagggcgag
     1741 attaagacaa attaaatctc aaaatagcag tgattagttt tgttcctagc attcgctttg
     1801 tttcttcttc tacatgaata tagggatttc cgtattcatc aaataaagtt ttctgtgaaa
     1861 gacgaatgat atagtgttca aaatgtttaa gtattccgtt tattgcattt acatcgccat
     1921 gtacagcaag taaaataatt gtaaaaggta atacttcttt agtaggtttc atttcaatgt
     1981 tcctccatga gttctttcaa ctcttttagt gcatttgttt tgtgataatg tatggtattt
     2041 tctgctaaat ccatcaatgt tgctatgtca gcatttgtca tgttgagaaa gaatgaaagt
     2101 agaattatat cttgttttct ttttgtaagt tttccgattg cttgtgccat taatacatct
     2161 tcaattcgta tgttgtagtc gtaagaaacc atacagatgt agttagaatc ataatcatct
     2221 aaaatactca atttacttaa ttctgcaagt gacaaagatt cgagagatac caaataatca
     2281 tttctgcgtt tattttcgtc ataaatatct ctagcatagt tacgcaaaac tgttttacag
     2341 aaactgtcga attgatgttc aattgtcttt tcatcaacca taagatttca ccctctttcc
     2401 atcgcaagga gttaaataac cttgcttact cctatcacgg tgggagggcg ttaaatcttc
     2461 gataaatttc aaaaaaaaga gaaaaaaata cacactctgc ctatagggca aaaatgtgta
     2521 ttctttaaaa cgtatttaat ttatattggt tgtaagccac caccatattg atgtatggaa
     2581 atatgcattg gctagctttt cataaaaata caaagatgca taagaaatta atagagggga
     2641 aaaacttatt ctgttattaa aaagtaggtt aattctaata aatgctattg cggtcgaatt
     2701 aaactatata catggcaatc aatcatgttt ctattcttta ttatgaattg tgacagtatt
     2761 cttcaatctt aaaaccacat ttttccaata ctttacttga ccctctattg taggaatata
     2821 cattagcatg aattttgtta aggttgtatt tttcaaaggc aattttgcat atttctttta
     2881 ctgcatttgt tgctatccct ttgccccaat agttcctagc aagccagtaa cctaattcag
     2941 catttttatt aatagaggta tcttcttcaa atgttaggct gatacttcca atagcccttt
     3001 cttgataaaa aatagcatag ctaagttgtt taacatctgg agttgccaaa caaaaactaa
     3061 caaaatctct agcgttttgc tccctataag ggtgggggaa gttgtcacga agattctttg
     3121 caatttcttt atcattcgca aactcaacta aatcggtaat ataagcataa ttccactcta
     3181 taagttccat ttttcttctc cttttatgaa acagctacaa gaaatctttc taagccaata
     3241 ccacttatca aacagcgttc ttttttattt ccaagcattt gataagtcca gtcaacaaat
     3301 ccaccgtcaa ctatttcaac ggtttcattt ccttgtttga ccgataattt gaaattgata
     3361 cctttataat aattattatc aacatcatca ttatgaattg ataactctat attaggaaaa
     3421 ataagtttga tagtttcaac cattctgtcg aaaaatccgt cattatcttt gtatccgttt
     3481 cttttgcgta gaataataga gaaacgaaca ttttctattt cacttaatat atctttataa
     3541 tagtttaagt gcttttctaa caacattttt tcacaagtgt aagaccctgt atctatacca
     3601 gatgaaacca tacaatataa gccaaaatgt gaatataaac ctttacctac aaaattttgt
     3661 gctcttatta ccctagcagt agtagccatg tggataggta tggtattatt ttcttctttt
     3721 ctttttaatt tatcagcaat aattattgcc aacatatttg aggggtctgc aagtgtttct
     3781 gtccctcgta gagcacttac tacattatat tgatctacgg agccaaaaac gctacagcta
     3841 cctaatggag cagagggaga aagcataatc gtcttgatat ccatattgaa tgcttttctc
     3901 aataattttg actccaaagc atgaatttct tctggatcta taccgctagg gatagtaaat
     3961 ctatttagtt ggtatgactt tagaatatca gttgcagtta aagtatttgc ttgtctatca
     4021 aacacttcta atagaagtga gttcaaatct gattttgata gagctgataa cttatcaact
     4081 atattcttat ccccaatttt atttgtaatt ctacttaaaa tatcactcat agttatcctc
     4141 catactgtta ctttcaaaat aattatagaa tggttacaac aactaatcta ggtcatttga
     4201 ccaaaaatga aaaaacactg aatatttact attcaatatt tttttacttt gggtttattt
     4261 gattaaatct tgaaaatact gtaatgcaac cctttcagct tcaacctttc ggacaatagg
     4321 actttgtgat aattcctctc ttaactcaag atacaggttg atagtagcct gcaatgcatt
     4381 aacacagctt ttatattcat ggttagcaac cgtcttttct aatgcttcaa tatattgggg
     4441 tgcgtccaat tcaatttttc taactccacg aggtaattta cctaagagaa gctgtattaa
     4501 tggggcaagt actgattgtc ttaaaaaaga taaaaaatca attgtttcaa atagttctct
     4561 acgtccaatc ttagtgcaag cgtaatgaac ccaaatccaa aatctatctt caatccactg
     4621 taagtctgga gttgggaagt atgcttcttt tttagtataa cacctctcac tttcttttat
     4681 tagctatcaa tccaacataa ttatgcatag gagtattata taatgaaaaa ataaaaaaaa
     4741 ataggtcact tgacccgaaa taaaaaagca ttgaataatt attattcaat acttttttga
     4801 aattatactt atgttgtagg aagattcttt aatacctctc gctgattaat tacactaaat
     4861 cttttgtttt cataagcaat tagatgttct tgtacacatt catttatagc acgattaatg
     4921 cttctaattg gagcgtttac ttcgctagca agctgttttt tggtaagcag atttaattca
     4981 cttctataat agtgtaagga tatacacctc agaagtcgtt ctttaacact taaagatgat
     5041 aattcttcaa ttaattcagc atttacaact aatttactag atatttctcg aatcagaaat
     5101 tttgtagctt caaaatctcc ccttaaccag tttaaaaaat catctctatg aagtttatat
     5161 acattacaat ctgtgaaagc gacaatttca acgggttttt tcccatcatt aaattgttcc
     5221 atttctccaa aaaaactacc acttctataa agatgaatag ttgagatgtt tcctttcaca
     5281 tttaagatga atgcttctgc aataccgtca atcataagaa ttacatattc attttcttgc
     5341 tcagcaaaaa gaatagtctc tttcttttta tacgtttttt taacaagctt ctttttaata
     5401 tcttcattca taaaatcaat taaatgcata ttcatccctc cttaccaaat ctttgattaa
     5461 attatatcat ctttcaatta gttaggtaag atagtaaaaa tatatttaca tagaaactat
     5521 tccattatta ttttccagtt gtcatttttc tgcaaagtaa gctcaaactg agaaagctgt
     5581 tgacaataga actagtagga atatatgagc gaaccatttc agtattcaac tgttgtaggt
     5641 tttcagtcag ataattcttc aaacgttcaa ttcgtttgtc ctgtgaatct tgcgatgctc
     5701 taaccagttt catagatagc gttttacctt gtgccacctg caaaaaagac catgcttcgt
     5761 caaggtcaac tatcttgaag ctagagcggt cagtatgaat aaagtctaat gcaaaggtac
     5821 taataacaat caacatagca acactaagaa gttctattgt tgtatattct tcaaagctag
     5881 tgttggcatc tggcaatacg aggtcagcaa cttgaataat attcagctgt ttctccaagc
     5941 tgatagactg cttcacattt ccgtcaccaa acagtagatg tgcaaaatca tagtctacaa
     6001 aactttcgat atggtcggct atgctgttac tgatagaagt atcttctttt cgtaattcat
     6061 caatgacaag taataaccct cgctgttcac tttgggttac attgcggatt gcttttctaa
     6121 gcactgggaa cttatcactg tcacgactgg agataccagc aaggaatgtt aggatatcaa
     6181 tcgctaaact ttcagaatca tttttacggc tcaaaatgac gtaagggtca agcaatcctt
     6241 tgttttcatc attactggtt aaattgacaa tgtttatctc atgggctatt tctggtagcg
     6301 tttctttcca tttgccgcgt tctgctttag ggtcaactat gaccgcctgt ccgccgaata
     6361 gtaccgcata gtaaacaagc atattgttac tgaataattt accaccaccc aatgaaccga
     6421 taaacgcaga cgctaacaca ttggtaatag aaccctttac ccattgacta gcaagggcag
     6481 gttttagata gacattcttt ccagtgtcca gattgtagcc aagatagata tcctcatgtt
     6541 cgccaagggt ttgtgtcgct ccaaaaccaa gtccagccaa aaaatccgaa gtgacatatt
     6601 gaatataatc attgatgtaa cgtttgctga caggaataaa ttcgccatgc aatcccaaca
     6661 tatccccaaa gggacgcacg agcttgagtg ataagtcgtc gtaaaagtct ttgacttcat
     6721 cacaacgcct ttttagctcg tcaagatcct ttgtagatac acggacaaca tagctaagtt
     6781 tatacataga ttctttacag ttaaaagtct gtttttaaaa aaatgtataa attataaatc
     6841 aaaatataga tactatcaat gacccactag gtgcaaaaag cattgatatg gttaaattat
     6901 cagacgctaa aagctgggct atccgaatga gtgaagatgg gtgtgcttat aaatccattg
     6961 acaattataa gcgctcactg aaagcgtcgt ttttcatggc aattcaagac gactgtatta
     7021 gaaagaatcc atttaatttt cagttaagtg atgttttgga agatacaaca gaaccaaaaa
     7081 tcgctctaac accagaacag gaaatgggct tattatcctt tatggagagc gataagactt
     7141 attgtaaata ttatgatgat gttgttatcc tcttagaaac aggactacgc atttctgaat
     7201 tatgcggttt gactttagaa ttggatatga aaaataaagc cattatggta gaccatcaat
     7261 tgttgagtga tactaagatt ggctattatg tagaagttcc aaagaccaca cagggtaagc
     7321 gagaaattcc aatgactgaa agagcttatc aatcatttga acgtatcgtg gaacggcgta
     7381 agaacgctaa agcagaacca atcattgttg atggttacca gaacttccta tttcttaaac
     7441 aagatggatt accaaaacaa gcaactcatt atcaaagcat gttaagagcg ttagtcaaga
     7501 agtataataa gacccatgag gacaagctac caaagattac gccacatacc tttaggcata
     7561 cactctgtac aaatatggct aacaaaggaa tgagtcctaa tatattgcaa tatattatgg
     7621 ggcataaaaa cattactatg acgcttggct attatgcaca tggttcattt agttcttcga
     7681 gagctgaaat ggaacggtta taatcctagt agtatgacta gagtttacta cttatttact
     7741 acttttgatg gcattcttat acggttaaat gccaacttat gcaaagtatc ttccaaaaag
     7801 aaaatgccga tactccttgt agatacagga tatatcgaca tttaccaact tatgaaaaga
     7861 taatcaaatt taatataagt ttttcaaata aaaagatacc aaattctttt tcgagaatct
     7921 atataacatt acttaagctt ggttggggta taaacaattg agtagctact tttgtatggt
     7981 gttcaacttt agtcaaaact cttaagtaat gcaaatgatt tagattcatt aatattcaat
     8041 ctcttcataa gtagtgaaat tcgagttatt tctgcataat tatactatga tttatagatt
     8101 aattctatta gcatccagaa taatattgtt tatatgagta aaatttaaag aatattgtga
     8161 aaattatagg atgttaaaat aaatttaggt aaaaaagaag tgtttgtata ttatagagta
     8221 ccttttctaa aatatgtggg attgttttaa gaattagaat aaaaattatt tttaaattag
     8281 tatttttata atgtatagta tttttaatgt ataattaaat tgtgcagaaa atagaattta
     8341 aagtcctata gaatttctga ttatggagga gaatatgaaa agaaaagttc aagtaaaaaa
     8401 tattactatt ggagaaggta gacctaaaat ttgtgtacca attattggga aaaataaaaa
     8461 agatattata aaagaggcta aagagttaaa agatgcatgt ttggatatta tagagtggcg
     8521 agttgatttt tttgagaatg tagaaaatat taaagaagtt aaggaagttc tctatgaatt
     8581 aagaagttat atacatgata tccctttatt attcacattt agaagtgtag tagaaggggg
     8641 agaaaaatta atatcaagag attattatac tactttgaat aaagaaattt ctaatacagg
     8701 tttagtagat ttaatagatg tagagttatt tatgggagat gaggtcatag atgaagtagt
     8761 taattttgct cataaaaaag aagtgaaagt aattatatct aatcatgatt ttaataaaac
     8821 tccaaaaaaa gaagagattg tatctcgttt atgtagaatg caggaattgg gcgcagattt
     8881 acccaaaata gctgttatgc cgcaaaatga aaaagatgtg ttagtgctac ttgaagctac
     8941 aaatgaaatg tttaaaattt atgcagatag accaataata acaatgtcaa tgtcaggaat
     9001 gggtgttata agtagattgt gtggtgaaat atttggttct gcattgactt ttggagctgc
     9061 aaaaagtgtt tcagcaccag ggcaaatatc atttaaagag ttaaattcag tacttaatct
     9121 attacataag agtattaatt aaattaatta tatagaaata ttagacggta tttttgaaga
     9181 tataaattaa atataaaaaa cttttcagat agtaaaattt aaattgggca attatatctg
     9241 aaaagcaact atttagtgtg tattttgaaa gtgatataga aaatcttata aatcaactat
     9301 ggcatattta aaatatgcca ttaaaaccta ctagacatta gattatagat ggtatactag
     9361 catttctatt atttatagat agtaagtttt cataataact gttttatcta aagtagaaga
     9421 tatatttgta ttatgtatat ttgtcattat ttttttgtaa ttatgtatat taatggttat
     9481 atatgtaata taatattatc actctatttt ttgtatattg tacattacaa catttatatc
     9541 tatcatcatc aattacagta gaatgtatgg gatacttatt ttcacttaac caatattttt
     9601 gcatattctt tgtccaagac tttggaaact tcaatacttt cttgtttatt ataacatcct
     9661 catcttcaaa aatattaact tctctttcta tttttatttt tctgttgtat atcttattga
     9721 tagattcttt gtcgagtttt atgtctctat acatatcagg gcaatagcaa caaacataat
     9781 ttcttttttt tcgacgttta aatttcacaa ctttctctat gctaatttct aatttttttg
     9841 taccatcttt tataaattta atatcttcta tgttctcgct tgaaaaaatt tctgtcaatc
     9901 ttaaagtatc tacagtttct ctaattattt gctttttata agaagagaat ccatatccaa
     9961 aagaaaggtt taatttatta gggatgtagc catttttata tttaaacatc ttaatttttt
    10021 ccaattcagc attatcttta aatttcaact tttcatacct aaaagttact ttgctaaaaa
    10081 gagtatattc tacatcaata tattcttttg caatcttaaa tttatcgcta ccttcaatca
    10141 caatcatagc ctatctccaa tcgttttata ttaaaataag gccatagaac atggtctaat
    10201 agtactcatt agcactataa gacaatgtta acacaaaaag acaaaaaaag gttatttatt
    10261 tcaaataacc ttttttttta tataaaatat aaagaattat attttattct tttttatgat
    10321 gtctataatc tgtgatatca gatttagttc tcttgaattt aagtctttta actcttcatt
    10381 tatatcattt tctaaatatg tttttccagt ggaagtaata tcttttataa gaacatctgc
    10441 agaaatattt aatatattta caaattttat gaatgtttta agacttggat tctttttacc
    10501 actttcgatt tgagttatat accaaggcga tactccaacc atatttgcaa attcttttga
    10561 agttaaattt gcttttttcc gttcttcttt aagtctttta cctatataat tcattattgt
    10621 tactatttcc ctcacttata tttctttgta tttaatgatg cactttatta actctagcat
    10681 tgcaatttgt tctttttcag ttaatttatt aatcatttca taacattcta aaggtacaga
    10741 gttatcaacg ccttctgttg taataatatt tgcaaataac aattcaagtg gtatgtctaa
    10801 agcagtagca attttcatta taatattgat agatgtattt gtctcagctc tttcaatctg
    10861 accaatatat gttggatgta aacctgcctt ttctgctaga aactcttgac tatatcccaa
    10921 ttttgttcta tagactttta ttctatctcc tattattttt cctatatttg ccaattatta
    10981 tccctccact ttagattata ttcatagttt aagttgtttt atatagacta tttatacttt
    11041 tttagtctaa atatagacta tatatgtttt tatactgaaa taagtgctat ttatttttgt
    11101 atagtctgta tctacaataa acaaatatgg ataaatcata tttttaatta gagaaatatt
    11161 ttcataattt cat
//
LOCUS       DAMJVG010000105        10813 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.110, whole genome shotgun sequence.
ACCESSION   DAMJVG010000105 DAMJVG010000000
VERSION     DAMJVG010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10813)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10813)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10813
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.110"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            167..1327
                     /locus_tag="PC512_003283"
     CDS             167..1327
                     /locus_tag="PC512_003283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 family protein"
                     /protein_id="HDF2443003.1"
                     /translation="MIETGFVYCSFLVVFVGVIFFMVDKLKWKVFDVINPMLLIYLGS
                     AILGSFGLFAQNEDVGTYQNIITVNFLPLMLVFLLIQCDLRKILKMGPKMLLSFFCAT
                     FTFMLGFVIAFIIFKNSMGADSWKILGAASGSWIGGSSNMIAAANALGVAEEGLSYAI
                     LMGSIGYTVWMSVCLMSVKFGPKFNKWTKCDTSFIDEVTSKLEKENKDNTAPTFVELM
                     ILLSVGFGVASFAQIVSKILPTSGILNETMWVVLVASTVSILLGMTKISKLKGSTLVG
                     NVFMYLLLAATGSKANFFGLSEAPVYIMFGLVVVLVHAISFIGLAKLFKLDLFTCEVG
                     SIANIGGVTTAPMIAGVHNPVLIPVGVLMGLLGNIIGTYCALMVTQILHMLA"
     gene            1670..1831
                     /locus_tag="PC512_003284"
     CDS             1670..1831
                     /locus_tag="PC512_003284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443004.1"
                     /translation="MIIPSRRIQDITLTNLKNGEVTLIELDEIYKKMGFLFVVSEGKL
                     KKIKKENHH"
     gene            2024..2653
                     /locus_tag="PC512_003285"
     CDS             2024..2653
                     /locus_tag="PC512_003285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HDF2443005.1"
                     /translation="MKIVTYNIHKGMDSNNRLTLTKMGLYLKQLDCDVICLQEVLYPQ
                     FLALKAVLNMGGVFATNVKKVNMIYGICTFTTSKMLNSNHFFLTSKKEQRGALCITID
                     AYGRIINVINTHLGLDRQERAKQLDEIIDYRNRLVGIVILCGDFNEKNVFLSMFNDMA
                     ISLNKSYLPTFEKSNSRIDYIFVNKNTELKGYTVEKIYLSDHYPVIGYI"
     gene            2893..4152
                     /locus_tag="PC512_003286"
     CDS             2893..4152
                     /locus_tag="PC512_003286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HDF2443006.1"
                     /translation="MGRRTTRVSRLGKEKKRSVLIVLAALVLIMGGFTYFFNSKFLYN
                     GKIAKNVYIEGVNVSDMTKAEALKAITDKYTPEDLNLAYDGKKYTISPKDIDLKYDTE
                     DVVKDAYESTKKGSYFQNLKKYIDIRVNKANMKIKAEYDEAKLSSKVSSIADSINVKM
                     KNASISVGSGGLSYTDSVVGREFDLAANKESIYNMIKNKEHKTLELKVNLQKPDITTE
                     QVKTVNSVIGQYSTTYSQAVEGRSYNVGLSARKTSDVLLMPGEEFSYNKLTGPSNKAN
                     GYKDAPVIVYGKLEQSAGGGVCQTSSTVYNAALLSGMEITQVTNHSSASTYVPKGRDA
                     TVSDGGLNLKFKNPYKHPVYIKNYAGGGSVSSVIYGNSGDKPNISIEVKQTGQNKYST
                     YRIFKDSSGKVIKKEHISNSSYKELKK"
     gene            4411..5406
                     /locus_tag="PC512_003287"
     CDS             4411..5406
                     /locus_tag="PC512_003287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase"
                     /protein_id="HDF2443007.1"
                     /translation="MYEEVTWLNFIGNRYEVVNSDDVLEINKIYKARDVFYRKNVLIK
                     VIKHNNYICEDFVSNLIDESTALDEINSPYILKIIDVGIHCTEETTLYYVVSEDFNGI
                     GLDELILGNYLHLEAIVNIMIQVLKALEMIHRNHSYHGSLKSSSIIVDTEYNIKICDF
                     GITKANNGVNTRSYGNRRYLCPHQLCINYTDKESDFFATGLILFESIFKKLPFGESNS
                     EEKMLQSIDKGLDWNSIKAINGNTELINVIKRLLGRNNKYTRANDIIIDLSKVMYEKA
                     YIEVEDEKEEEQKQDKVIQVKKEYKSKMRKKLHKKLVVAGLAIVMISMIIISSII"
     gene            5652..6719
                     /locus_tag="PC512_003288"
     CDS             5652..6719
                     /locus_tag="PC512_003288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA ligase RtcB family protein"
                     /protein_id="HDF2443008.1"
                     /translation="MSNIKIIASNKCWIEDIARKQLEDISKLNGILRVVGLPDLHAGK
                     IPVGLAVETKNIIYPHIIGNDIGCGMTLFKTGVLKKKFKKDKWIKSLSKIKDLSDIEI
                     KNTYKEECPILNLGTIGSGNHFVEIQCISEIYNKEQFEQLKFSSDDIMMLVHCGSRNY
                     GEDILKKFYDKDGLEVESEKAIDYIKKHDNALMWAERNREAISKKIMQSIGTSGDVET
                     IFSINHNFIEKREDKFIHRKGAVSSERGAVIIPGSRGSLSYIVMPTENTEISLYSLSH
                     GAGRKWSRSVCKSRLKSKYNKDTIKQTKFKSQIICNDVNLLFQEAPEAYKNIEQIIES
                     LIEYELIQVVATMKPLITYKG"
     gene            7253..9163
                     /locus_tag="PC512_003289"
     CDS             7253..9163
                     /locus_tag="PC512_003289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HDF2443009.1"
                     /translation="MNSNTFERLQLNEVKELIKIHCVSSLGKNLIDKLTPSGNIGVVR
                     RKLAENKEARKIIENSNHIPLEGLFNAGSTIDKIEKGMIIEPVELVNIEDFLRGCRKM
                     KAFMLEKEFYSPTLSSYALNITECKSIEDEINYCIKSNKVDSNASKELKKIRRNIEIT
                     EGKIKDRLNKFITSTVNKKYIQEFIISKRNDRYVIPIKSSYKNEVNGTILDTSSKGNT
                     VFIEPISVSNLSTELTMLKADETIEEYKILSYLTELIFEKISQIKLNIEILSEYDMVF
                     AKAKYSQKIKGITPKINNNGYIKIIKGKHPLLTGDAVPLDFEIGKNYRSLIITGPNAG
                     GKTVTLKTVGLLTLMVQCGFDISAKEGSEFSVFEKVFVDIGDNQSIENALSTFSSHIK
                     NIAEIMSLSNNSTLVLFDEIGSGTEPNEGAGLAISLLEEFYKMGCITIASTHYGEIKK
                     FATLHPEFENAGMMFDKETLEPLYKLTIGKSEDSNALFISKKMGIKNRVLDRAKEYVI
                     DRNYNLDLVKRSKLQSNIEDKNSSEVILNYTDYNVGDKVKLLDEDDFGIVYKPMDKFN
                     NVEVLFNDNFISVNIKRLQLSIKASELYPEGYDLDVLFTSFKERKLEKDIQRGSKKAL
                     KKIQKEIRENRK"
     gene            complement(9226..9849)
                     /gene="ytaF"
                     /locus_tag="PC512_003290"
     CDS             complement(9226..9849)
                     /gene="ytaF"
                     /locus_tag="PC512_003290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation membrane protein YtaF"
                     /protein_id="HDF2443010.1"
                     /translation="MIESILLVTSLCIDAFVTSFGYGVNKVKVPLYSNIIISVVCSAI
                     LAISLFAGTIVRDFLPQNITMLICFFILFLLGSARLIESFFKSYFKKKSIHSKNYNFN
                     MLDLKLNFNVSIEPDVLDTSKSKVLKSAEAFTLALALSLDGLAIGFGSGLVGVNYIQV
                     ILFSLISNIIAVLLGCLLGNMFVKNVNLNLSWLSGLILLVIGFMKIC"
     gene            10037..10681
                     /locus_tag="PC512_003291"
     CDS             10037..10681
                     /locus_tag="PC512_003291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2443011.1"
                     /translation="MEQHSKVGNFGDLLKVLLDEKELSMGELSKKSGIDKSTISRIAN
                     NKQKPNINHLEKMAIHLNINLEELLKASGYEFRNSNNQIFNADSDFSNFDDILGFANL
                     INDKNFNGNIEKELSKCKLYVQTDEGKKLLFDNFNKKIDSIEKQGQFTDRLRQMYADF
                     CTDGLTIKKYLLIGSMLLYFVISTDVIPDFVFPIGFMDDLVALNIVTKLLKNDK"
BASE COUNT         4432 a         1062 c         1765 g         3554 t
ORIGIN      
        1 ttaatgtgca aatctttatt aatatatgtc aatagttagg tatatatgta tttaattagc
       61 atgatataga taaaagtatt tattttaatt gtctattatc tgaaaaagtc tttacttaga
      121 aatcataaaa atcaaattaa ttaggaaaag aaagggtgtg tataatgtga ttgagactgg
      181 atttgtatat tgtagtttct tggttgtatt cgtaggtgta atttttttta tggttgataa
      241 attgaaatgg aaggtatttg atgttattaa tccaatgctt ttaatatact taggttcagc
      301 tatacttgga tcatttggtt tatttgcaca gaatgaagat gttggaacgt atcaaaacat
      361 aataacagtg aacttccttc cattaatgtt agtgtttttg ttaattcaat gtgatttaag
      421 aaaaatatta aagatggggc ctaaaatgtt attatcattt ttctgtgcta catttacatt
      481 tatgcttgga tttgttatag cattcataat ttttaaaaat tcaatgggtg cagattcatg
      541 gaaaattctt ggggcagcat ctggttcatg gataggtggc tcatcaaata tgattgcagc
      601 agctaatgct ctaggagttg cagaagaagg acttagttat gcaatactta tgggttctat
      661 aggatataca gtatggatgt ctgtttgtct aatgtctgtg aaatttggac ctaaatttaa
      721 caaatggaca aagtgcgata caagttttat agatgaggtt acatcaaaac ttgaaaaaga
      781 aaataaagat aatacagcac ctacgtttgt agaacttatg attttacttt ctgttgggtt
      841 tggagttgcg tcttttgcac aaattgtatc caagatactt ccaacttcag gtatacttaa
      901 tgaaactatg tgggtagtac ttgttgcatc tacagtatca atattattgg gtatgacaaa
      961 aatatcaaag cttaaaggga gtacactggt aggaaatgtg tttatgtatt tactccttgc
     1021 agctacaggt agtaaagcaa atttctttgg attgtcagaa gcacctgttt acataatgtt
     1081 tggattggta gtagtccttg tacatgctat ttcatttata gggcttgcta aactatttaa
     1141 acttgattta tttacttgtg aagtaggaag tatagctaat ataggaggag taactacagc
     1201 tccaatgatt gctggggttc acaatcctgt attaatacca gtaggtgtac ttatggggct
     1261 tctaggaaat attataggga cttattgtgc tcttatggta actcaaatat tacatatgtt
     1321 agcttaatga aaatatggta taaaattaat aatttaaata agaaaagtca tttcaattta
     1381 agcagaagct tttactgaaa tggctttttt tgtttgacaa gataatctat ttcaagaaga
     1441 tgttttgaca tatttagtgt ataatattgt aaaatttact aaaaacgaga tatatttaat
     1501 ttttatattg aatcgaacgt ctgtatgatg tataataaat atacagaacg aatgtttgcg
     1561 gaacgggtgt tttttgaatt tattttaata atttatgaat atatatcaga atgcataaat
     1621 atatttaaat ataaagatta aaaagaattt aaaggagtgt tgataactta tgataattcc
     1681 atcaagaaga atacaagata taacattaac aaatttaaaa aatggtgaag taactttaat
     1741 tgaattggat gaaatataca agaagatggg atttttattt gttgttagtg aaggcaaatt
     1801 gaaaaagata aaaaaggaga atcatcatta gaaatgaatg aaataataaa tattataata
     1861 gtttataaaa cctaacttat gtagaatata aatacttaag ttaggttttt ttgtgataaa
     1921 gtttataagt actcaatttt ataagataaa taatggtttt aagtgaaaag taaataagtt
     1981 taaattttag taagtattat attgcataag aggtgatatt attatgaaaa tagtaaccta
     2041 caatattcat aaaggtatgg attcaaataa tagattaact ctaactaaaa tggggttata
     2101 tttaaaacaa ttggattgtg atgtaatttg tttgcaagaa gtattatatc ctcaattttt
     2161 agctttaaaa gctgttttaa atatgggtgg tgtctttgct acaaatgtaa aaaaagtaaa
     2221 tatgatatat ggtatttgta catttacaac atctaaaatg ttaaacagta atcatttttt
     2281 cttaactagc aaaaaagaac aacggggagc tctttgtata actatagatg catatggaag
     2341 aattataaat gtaataaata ctcacttggg acttgatagg caggagagag caaaacaatt
     2401 agacgaaata atagactata ggaacagatt agtggggata gttattttat gtggtgattt
     2461 taatgagaaa aatgtctttt taagtatgtt taatgatatg gctatttcac taaacaagtc
     2521 ttacttacca acatttgaaa aatcaaactc tagaatagat tacatttttg ttaataaaaa
     2581 tactgaacta aaaggataca cagtagaaaa aatttacctg tcagaccatt atcctgtaat
     2641 aggttacatt taaatttcaa tataaatgaa attagttgtt ataaaataaa caattttttt
     2701 gttaagaaat agtaaaagaa atataataaa aaatatcaaa aataaaacta attataagac
     2761 ataaatttac aataaagtta catttgatta aattccttgt ttaacaaaag ctattcaaat
     2821 ataatctaag gtagttttga aatgggaact ctattatgca aatttaagct agtgttaaaa
     2881 tgaggtgaag ttatgggcag aagaacaaca agagtttcaa gattaggtaa agaaaaaaaa
     2941 cgaagtgttt taattgtatt ggcagcttta gttctaataa tgggtggatt tacttatttt
     3001 tttaacagta aatttctgta caatgggaaa atcgctaaaa atgtatatat agaaggagta
     3061 aatgtatctg atatgactaa agcagaggca ttaaaagcta taacagataa gtatactcca
     3121 gaagacttaa atcttgctta tgatgggaaa aaatatacaa tatcaccaaa agatattgat
     3181 ttaaaatatg atacagaaga tgttgtaaaa gatgcttatg aaagtacaaa aaaagggtcc
     3241 tattttcaaa acttaaaaaa atatattgat ataagagtga ataaggcaaa tatgaagata
     3301 aaagctgaat atgatgaggc aaaacttagt tccaaagtgt cttctatagc agatagtata
     3361 aatgttaaga tgaaaaatgc ttctattagt gttggaagtg gtggactaag ttatacagac
     3421 tctgttgtag gtagagaatt tgatttggca gcaaataaag agtctatata taatatgata
     3481 aaaaataaag agcataaaac tttagaactt aaagtaaatc ttcaaaaacc agatataaca
     3541 actgaacaag taaaaactgt aaattctgtt ataggtcaat attcaactac ttattcacaa
     3601 gctgtagagg gtaggtcata taatgtagga ttatcagcaa gaaaaactag tgatgtatta
     3661 ttaatgccag gtgaagaatt ttcatacaat aaacttacag gacctagtaa taaagcaaat
     3721 ggttacaaag atgcacctgt tatagtttat ggtaagctag aacaatcagc aggaggaggt
     3781 gtttgtcaaa catcttcaac agtttataat gctgctcttc tttcgggtat ggagataact
     3841 caagttacaa atcattcatc tgcatctact tatgtgccta aagggagaga tgctactgtg
     3901 agcgatggag gattaaactt aaagtttaaa aatccatata agcatcctgt atatattaaa
     3961 aattatgcag gtggaggaag tgtatcatca gtaatctatg gtaattctgg tgacaaacca
     4021 aatatatcta tagaggtaaa acaaactggt cagaataaat attctacata tcgaatattt
     4081 aaagattcaa gtggaaaggt cataaaaaaa gaacatatat caaatagttc ttataaagaa
     4141 ttaaaaaaat agataatttt ttagagaaat atttgtaata taaaagggag tgtctcaaaa
     4201 tgaacttttt agtttatgag gcactctttt tctgtgaaat caaatatatt ttcatcattt
     4261 caacaataca aaagaagcgt atctctattt tgagacagcc ttttttgtaa aaattaacac
     4321 tattagttct tgttttaata ttacaatcat taatatatag aaaatattcc tatatattgg
     4381 tataattgta aatagattta gttatataaa atgtatgagg aggtgacatg gttgaatttt
     4441 ataggcaata gatatgaggt agtaaattct gatgacgttt tagaaattaa caaaatctat
     4501 aaagctagag atgtttttta caggaaaaat gtgttaataa aagttataaa gcacaataat
     4561 tatatctgtg aagattttgt ttcaaattta attgatgaaa gtactgcttt agatgagata
     4621 aactctcctt atatactaaa aataatagat gttgggattc actgtacaga agaaacaaca
     4681 ttatattatg ttgtaagtga agactttaat ggtatcggac tagatgaatt aattctaggt
     4741 aattatcttc atttagaagc aattgtaaac ataatgatac aagttttaaa agctttagaa
     4801 atgatacata ggaatcattc atatcatggt agtttaaaat cgagtagtat aatagtagat
     4861 acagaataca atataaaaat ttgtgatttt ggaattacaa aagcaaataa tggggttaat
     4921 acaagaagct atggaaacag gagatattta tgcccacatc aactatgtat aaattatact
     4981 gataaagaaa gtgatttttt tgcaacaggt cttattctat ttgaatctat atttaaaaaa
     5041 ttgccttttg gagaatcaaa ttcagaagaa aaaatgctac aatctattga taagggatta
     5101 gattggaata gtataaaagc aattaatgga aatactgaac ttataaatgt tataaaaagg
     5161 cttcttggaa gaaataataa gtatactaga gccaatgata ttattattga tttaagtaaa
     5221 gtaatgtatg aaaaagcata tatagaagtt gaagatgaga aagaagaaga gcagaaacaa
     5281 gacaaagtta tacaagttaa aaaagaatat aaaagtaaaa tgagaaaaaa attacataaa
     5341 aaacttgttg ttgccggtct agctatagtc atgatttcaa tgattattat tagttccata
     5401 atataaaaat tgtatattaa gtattttaaa atcaatgtct ataaaggata tacatagaaa
     5461 ttttagtgta gtcttaaatt atgaaaggaa gtggttatta tgttaacaaa aaataatgag
     5521 gtattaaacg tctaggagta ttttaacaaa tagccacctg cttttacagt ttagaataaa
     5581 aaagctgtgg ctaaaggtca cagctttttg ctacttttta aaggcaggag aatattaaaa
     5641 aggagcaaat tatgagcaat ataaaaataa tagcaagtaa taaatgttgg attgaagata
     5701 tagcaaggaa acaacttgaa gatatttcaa agttaaatgg aattttaaga gtagtaggat
     5761 tacctgactt acatgcaggt aaaatacctg taggtttagc agttgagact aaaaatatta
     5821 tttatccaca tataattgga aatgatatag gatgcggaat gactttattt aaaactgggg
     5881 ttctaaaaaa gaaatttaaa aaagacaaat ggattaagtc acttagtaag attaaagatt
     5941 tgtccgatat agaaataaaa aacacatata aagaagaatg tccaatttta aatttaggaa
     6001 ctatagggag tggaaatcat tttgtagaaa ttcaatgtat aagtgaaatt tataataaag
     6061 aacaatttga acaattaaaa ttttcatctg atgatattat gatgttagtt cactgtgggt
     6121 caagaaatta tggagaagat attttaaaaa aattttatga taaagatgga cttgaagttg
     6181 aaagtgagaa agctatagat tatattaaaa aacatgataa tgctttaatg tgggcagagc
     6241 gtaatcgtga agctatcagt aaaaaaatta tgcagtcaat aggtacatct ggagatgttg
     6301 aaacaatatt ctctataaat cataatttta tagagaaaag ggaagataaa tttatacata
     6361 gaaaaggtgc tgtttcaagt gaaagaggag ctgtgattat accaggttca agaggcagtc
     6421 tatcatatat agttatgcct actgaaaata cagagatatc tttatattct ctatcacatg
     6481 gagcaggtag aaaatggtct cgttcagttt gtaaatctcg ccttaaaagt aagtataata
     6541 aagatactat aaaacaaact aaatttaaaa gtcagattat atgtaatgat gtaaatttat
     6601 tatttcaaga agctccagag gcatataaga atatagagca gattattgaa agtttgatag
     6661 aatatgaact tattcaagta gtggcaacta tgaagccatt gattacttat aaaggataat
     6721 ttttaaagtt aaaaaagatt aaaattatat tataaatagc taattttatg gaacatttaa
     6781 aagtgtttta ttattagcta tttttttatt ttgtagagac gataatttat agagctaaat
     6841 tctttgatat ataatgatta caaagttaga ctgtattgga aaatgcacat acatgaattg
     6901 atgacaatat aagtgattcc caaatataaa tgaaagtata agcttatttt cactataaaa
     6961 attttcactg tacaaaaaca ttaatgacat tatttttatt gacataaata tataatttat
     7021 ggaataatat tagaagcact gatataagtg tttaaataag aatagaaaag gagaagtgtt
     7081 ttatgaaaaa aaatactaac attaatgagt ccggagttaa acttcttaat aaataaggag
     7141 tttgatatat aataactcct tatttattaa gttgttcgca aaataactat tatcaaagta
     7201 aatgataggg tgatttaaaa gacgataact tataaataaa ggagaaaaaa taatgaatag
     7261 taatacattt gaaagattac aactaaatga agttaaagaa ttaataaaaa tacattgtgt
     7321 aagttcacta ggaaaaaatt taatagataa attaactcct agtgggaata ttggagtagt
     7381 aagaaggaaa ttagcagaaa ataaagaagc tagaaagata attgaaaata gtaatcacat
     7441 accacttgaa ggattgttta atgcaggttc tacaatagat aaaattgaaa aaggaatgat
     7501 aatagaacct gttgaacttg taaatattga agatttttta agaggttgta ggaagatgaa
     7561 agcttttatg ttagaaaaag aattttattc acctacatta agttcttatg ccttaaatat
     7621 aacagaatgt aaaagtatag aagatgagat aaattactgt ataaaatcta ataaagttga
     7681 ttctaatgct agtaaagaat taaaaaagat aagacgaaat atagaaatta cagaaggaaa
     7741 gataaaagat agattaaata aatttataac atcaactgta aataaaaagt atatacaaga
     7801 gtttataata agtaaaagaa atgatagata tgtaatacca attaaatctt cttataaaaa
     7861 tgaagttaat ggtactatat tagatacatc atcaaaagga aatacggtat ttattgaacc
     7921 tattagtgtt tcaaatttaa gtacagagtt aactatgtta aaagctgatg aaactattga
     7981 agaatacaaa atattatctt atttaacaga acttatattt gagaagataa gtcagataaa
     8041 attaaatata gagatacttt cagaatacga tatggtattt gcaaaagcta agtatagtca
     8101 aaaaataaaa ggaattactc caaaaataaa taataatggc tatataaaaa taattaaagg
     8161 taaacatcca cttctaacag gagatgcagt acctttagat tttgaaatag gcaaaaatta
     8221 tagaagtctt ataataacag gtcctaatgc aggaggaaaa actgtaaccc ttaagactgt
     8281 tggtttacta actttaatgg ttcaatgtgg atttgatatt tctgcaaaag aaggtagtga
     8341 atttagtgta tttgaaaaag tttttgtaga tataggggat aatcaaagta ttgaaaatgc
     8401 cttaagtact ttttcatcac atataaaaaa tattgcagag attatgagtt tatcaaataa
     8461 ttctactctt gttctgtttg atgaaatagg aagtggaact gaacctaatg aaggagctgg
     8521 tttagcaata tcattattag aagagtttta caaaatggga tgtataacta tagcatcaac
     8581 tcattatgga gagataaaaa agtttgctac attgcatcca gaatttgaaa atgctggtat
     8641 gatgtttgat aaagaaacgt tagaaccatt gtataagtta actattggaa aatctgaaga
     8701 tagtaatgct ctttttattt ctaaaaaaat gggaataaaa aatagagttt tagatagagc
     8761 taaagaatat gtaattgata gaaactacaa tttagattta gttaaaagaa gtaagctaca
     8821 atctaatatt gaagataaaa atagttctga agtcatttta aactatacag attataatgt
     8881 aggggataag gtaaaattac tagatgaaga tgattttgga attgtatata agcctatgga
     8941 caagtttaat aatgtagaag tattgtttaa tgataatttt atttcagtaa atataaaaag
     9001 attacaactt agcataaaag catcagaatt gtatccagaa gggtatgatt tagatgtatt
     9061 atttactagt tttaaagaaa gaaaattaga aaaagatatt caaagaggtt caaaaaaagc
     9121 tcttaaaaag attcagaaag aaattagaga gaatagaaaa taaatataaa aagcacaaaa
     9181 gaaagcaatc taaagagaaa agtttatctt tagattgctt tcttattaac atatcttcat
     9241 aaatccaatg actaacaaga ttaaaccact taaccaagat aagtttaaat ttacgttttt
     9301 aacaaacata tttcctagta aacaaccaag taatactgca attatatttg atattaaaga
     9361 aaatagaata acttgtatat aattcacacc tacaaggcca ctaccaaaac cgatagctaa
     9421 tccatctaaa cttaaagcaa gtgcaagtgt aaatgcttca gcagatttaa gcactttaga
     9481 tttacttgta tctaagacat caggttcaat acttacatta aaatttaatt taaggtctaa
     9541 catattaaaa ttataattct ttgagtgtat agattttttc ttaaaataag atttaaaaaa
     9601 actttcaatt agtctagcac ttcctaataa aaataaaata aagaaacata ttaacattgt
     9661 tatattttga ggtaaaaagt ctctaactat tgtacctgca aaaagcgata ttgctaaaat
     9721 agctgaacaa actacgctga taattatatt tgaatataag ggaactttaa ctttatttac
     9781 gccatatcca aagcttgtca caaaggcatc tatacaaaga gaagtaacta ataaaattga
     9841 ttcaatcaca gtagattaac atcctttctc ttaaattttg tacttatatt agttatagta
     9901 ttgtaaaaat ggataaattg ttacagataa tccaataaat tgttgataaa attccaacat
     9961 catacaacac ctaaataaca aaagaatcat atcatataat aatataaaac caatcataat
    10021 aaagcaggtg aaaataatgg aacaacatag taaggttggg aatttcggtg atttgttgaa
    10081 agttttatta gatgaaaaag aattatcaat gggagaacta agtaaaaaaa gtggaattga
    10141 taaatctact atatctcgta tagctaataa taaacaaaag ccaaatataa atcatttaga
    10201 aaagatggca atacatttaa atattaacct agaagaactg ttgaaagctt caggatatga
    10261 atttagaaac agcaataatc aaatatttaa tgcagatagt gattttagta actttgatga
    10321 tattcttgga tttgcaaatt taatcaatga taagaacttt aatggaaata ttgaaaaaga
    10381 gttaagtaag tgtaagttat atgtccaaac agatgaaggt aaaaaattac tttttgataa
    10441 ttttaataaa aaaatagatt ctattgaaaa acaaggtcaa tttacagata gattaagaca
    10501 aatgtatgct gatttttgta cagatggact tacaataaag aaatatttat tgattggaag
    10561 tatgctactt tactttgtta tatcaacaga tgtgattcca gacttcgtgt tcccaatagg
    10621 atttatggat gatttagtag cattaaatat agttacaaaa ttacttaaaa atgataagta
    10681 agttttagaa tcatatttaa tatataaata aatcaaagta tataaaattt attatttttt
    10741 atatgaaaca aattaaaagc acaatgaagt agattaaaaa tttaaaacta agaatctaat
    10801 atatattttg taa
//
LOCUS       DAMJVG010000106        10798 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.111, whole genome shotgun sequence.
ACCESSION   DAMJVG010000106 DAMJVG010000000
VERSION     DAMJVG010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10798)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10798)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10798
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.111"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            297..755
                     /locus_tag="PC512_003292"
     CDS             297..755
                     /locus_tag="PC512_003292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2443012.1"
                     /translation="MEFINFVSDKVIDLKMDCKTKEDFFKEIHNKVFDLGFVKEEFGE
                     KILARENVFPTGLNLGDYGVAIPHTDAEYIKEQFISVCTFNEPVVFSSMEDQDEKVPV
                     NLAFVLGLNQPHSQLSVLTELMGIMQNKELVDKLMSSTDKEEVLKTLKSL"
     gene            816..1091
                     /locus_tag="PC512_003293"
     CDS             816..1091
                     /locus_tag="PC512_003293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2443013.1"
                     /translation="MKKILVACGAGIATSTVVCDKVERLVKENNIQAEVIQCKIAECA
                     TKQEGADLIVSTTILPTTYNIPAIKATAYITGVNTAALDKKILDALK"
     gene            1150..2424
                     /locus_tag="PC512_003294"
     CDS             1150..2424
                     /locus_tag="PC512_003294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012951111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HDF2443014.1"
                     /translation="MDKLLAVVQYILNMGPTVILPITIVVLGMIFRIKFTKALKSGLT
                     IGIGFVGINLVVNLLTSTLGPAAQGMVERFGLNLTVIDVGWPTTASATWASPVAPILI
                     PVCLLVNLLLLYFNKTKILNVDIWNYWHFIVAGAVGYIVTGSYVWAIFCAILMELLVL
                     FIAEKTAKNVQEFYDLEGIALPTGSTASFAPLGYLVGKFVEKIPGINKIQADPDSIQK
                     RFGIFGEPMMMGIILGIILGALAGYDVAGIFNVGISMGAVMLLMPRMVRILMEGLIPI
                     SESIRDFLQAKYGDRELYIGLDAAVATGHPAVISTALILVPITLFLAVILPGNKVLPF
                     GDLATIPFYMAFIVCFRKGNIVQSVITGTIVIAISLYMATNFADVHTQLLQQANMMPE
                     GTTMVTSIDTGGNLLKWGILKLSQLVSSFGIF"
     gene            2554..3606
                     /locus_tag="PC512_003295"
     CDS             2554..3606
                     /locus_tag="PC512_003295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HDF2443015.1"
                     /translation="MKAAVLHGTNDMRFEDIEIKPCESDEVKIKVMAAGICGSDPPRV
                     LKHWKYPVPAIPGHEFSGVIAEVGKDVKNVKVGDRVVAIPFIPCNECEYCKRGLFSLC
                     DDHGMLGAKSFGAFAEYVNIKATNVLPIGDMNFEDAAMIEPLAVAMHGVLNIGVQVGD
                     TVAVMGSGTMGQLVIQGLKIAGAGTIIAVDISDNKLRESKELGADIIINAKDINPVEK
                     IKELTGGKGVDIALECAGSKITQEQCLLITKKKSKIGFLGIAYSDITLSEEAFENIFR
                     KELELKGFWNSYSAPFPGQEWTKGINLVNEGKIKLKEMVSHRFSLEDTYKAFEMIRDR
                     KEEFNKILILPQGVEK"
     gene            3606..4637
                     /locus_tag="PC512_003296"
     CDS             3606..4637
                     /locus_tag="PC512_003296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012986518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HDF2443016.1"
                     /translation="MKAVVKTKPGYDNVEVLEVEEPKATGDKVKIKVEYSGICGSDIH
                     SFKGEYANIKAPVTLGHEFSGIVVEVGEDVKNIKVGDRVTSETTFATCEKCIYCETKD
                     YNLCPTRKGIGTQVNGSFAEYVLSREESIHVLPENVSLLSAALTEPLACCVHAALEKT
                     TIESSDTVLIIGPGPIGLLLAQVVKSQGATVIMSGVTKDKERLEIAKNLGVDRTVNVM
                     EESLADVVNEMTDGNGVNKGFDCSGFMPAVNEALRLLRKKGTFVQVGIFAKKLNEMDQ
                     EAIIQRELQYIGSRSQKPSSWITALDLMANGKVNTEALVTRTVGLDEFKEGITALMNG
                     EEIKVAVKS"
     gene            4729..5541
                     /locus_tag="PC512_003297"
     CDS             4729..5541
                     /locus_tag="PC512_003297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HDF2443017.1"
                     /translation="MSTLRDHSNNIRKNIIKMVAEAKSGHPGGSLSIADMLTVLYFDK
                     MNVCAENPKMADRDRFVLSKGHAAPALYATLAEKGFFPEEELITLRKFGSKLQGHPDM
                     KKVAGIDMSTGSLGQGLSAANGMALAGKLDNKDYTVYTILGDGEIQEGQIWEAAMTAS
                     HYKLDNLIAFVDLNGLQIDGSNEEVMNVSPVDDKFKSFGWNVIVINGHSFEEIGNAVD
                     EAKKVTGKPTVIIAKTVKGKGVSFMENNAAWHGTAPNAEQAEQALKDLEGGL"
     gene            5544..6464
                     /locus_tag="PC512_003298"
     CDS             5544..6464
                     /locus_tag="PC512_003298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HDF2443018.1"
                     /translation="MGIATREAYGQVLKELAENKDIVVLDADLGKATKSISFKEVAPD
                     RFFDMGIAEGDMIGTAAGLATCGKIPFASTFAIFAAGRGYEQIRNSVAYPNLNVKIAA
                     THAGVTVGEDGGSHQAIEDISLMRGIPNMVVLNPADALEARQAILTSIDYNGPVYIRL
                     GRAATPDVNSENYKFEIGKGTVLREGSDITVIATGIMVAKALEAAEELAKEGINVEVV
                     NISTIKPLDEALIKETAKKTGKVVTAEEHSIIGGLGSAVCEALAETKDVVVRRIGVKD
                     VFGQSGTPADLLKHYGLTTEDIVKNIKELL"
     gene            6639..7085
                     /gene="rpiB"
                     /locus_tag="PC512_003299"
     CDS             6639..7085
                     /gene="rpiB"
                     /locus_tag="PC512_003299"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 5-phosphate isomerase B"
                     /protein_id="HDF2443019.1"
                     /translation="MKISIGCDHGGYELKEYIKENLINKGIEVEDVGTNSKESVDFPI
                     YAKKVSQNVQSKKSDLGILCCGTGIGMSIAANKFKGIRAAVVSDCFSAKATREHNNTN
                     VLCLGERVIGKGLAMRIVEEWLNSSYNGERHARRLQMIDDIEKENL"
     gene            7115..7780
                     /locus_tag="PC512_003300"
     CDS             7115..7780
                     /locus_tag="PC512_003300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HDF2443020.1"
                     /translation="MSIICASIMCADQMKLKEELEALEEAGVKLLHCDVMDGIFVKNL
                     AMGPELLKSISENTTIPLDIHLATETPDKYIDMMSYIKPKYISFHVESSTNVKADIQK
                     LRNYGIGPVLAISPQTSVDKIEEYISLVEGILVMTVNPGFAGQKFNLSVLDKLDKLTE
                     ILKDYDNPPFIEVDGNINKDTIKLMNGKKVDIYVVGTSALFNDKPPISYKDKIEELKE
                     SIK"
     gene            7890..9392
                     /locus_tag="PC512_003301"
     CDS             7890..9392
                     /locus_tag="PC512_003301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HDF2443021.1"
                     /translation="MGDLYKLQNGTDIRGIAYENDSKEVNLTVEEVKKIAKAFHIWLK
                     EKTKKDKVTVAIGTDSRITGSQFRSTVIETLTNDDCNVIDCEIATTPAMFMTTIMDGY
                     NSDGAIMITASHLPYYYNGLKFFTESGGLEKTDIKEMLDIAVKNDSVDYEEVNKKGEV
                     IVKNLIEDYSNLLIDKIRKGVNSSKNYEKPFSGLKILVDAGNGAGGFFAEKVLHILGA
                     DTTGSQFLNPDGMFPNHIPNPENKEAMESICKAVLDNKSDLGIIFDTDVDRAAIVGKN
                     GKPINKNALIAVISSIVLEEHPKTAIVTDSITSEGLAKFINELQGRHHRFKRGYKNVI
                     NEAIRLNSEGEECHLAIETSGHAALKENYFLDDGAYLIAKILIKVAKLSLEGKTIEEL
                     IENLEEAQEEKEVRIGINKEDFRTYAEDILKDLDSHVKSIDGWSVAPNNFEGIRVNCD
                     ESNGDGWFLLRISLHEPLLALNIESNKIGGAEQIYSKLKLFLEKYDLKGL"
     gene            complement(9704..>10798)
                     /locus_tag="PC512_003302"
     CDS             complement(9704..>10798)
                     /locus_tag="PC512_003302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF2443022.1"
                     /translation="NYNLKDMSITYVFFSNLLSMYNKKTINKKLAIVFLISIVVQAII
                     QYLVLIFFMYIYYAEAIAIVILFTLVNTVFHFYIYNFLSVKFNYINNISKNIKNIENG
                     NLKYKLEVIGDDEISTLAKSINNITGGLETAVDANIKNERMKAELITNVSHDLKTPLT
                     SILSYVDMLKNNDFDRETINDYINILDKKSQRLKLLIDDIFEASKLSSGDVEFNITKT
                     DIRELLIQSIVEFEDKIQNSSLDFIIETPEYAVFTMIDGKKTWRVFENLICNILKYSM
                     PNTRVYIDMFIKEENIILTFKNISNDKLNLKPEELIERFRRGDISRKTDGSGLGLSIA
                     QNIIELENAHMEIIIDADLFKVMLTFRKVN"
BASE COUNT         4308 a         1218 c         1980 g         3292 t
ORIGIN      
        1 agttgttaaa cataaaaaac catttgtaaa aaacaaaaaa atcatttctc taacaaaaaa
       61 aaccacaaaa aatataaaaa agtatggcta gttaagtgat taacaagtaa aaattaaaat
      121 aaaaatcaaa aaaaatttat caatgaaagt cagctaaaat cctggaagag agcattattt
      181 ttgggaaaac attttctttt gtttcacaaa aaaagccact ttttggcaca caacatgctt
      241 tatataaagt caagaaaaac taaggtataa gacaaaggca attaggaggt gtaaatatgg
      301 agtttataaa ttttgtaagt gataaagtta tagaccttaa aatggattgt aaaacgaaag
      361 aagatttctt taaagaaata cataataaag tttttgattt aggctttgta aaagaagaat
      421 ttggagaaaa aatattagca agagaaaatg tatttccaac aggtttaaat ttaggagatt
      481 atggagtagc aataccacat acagatgcag aatatattaa agagcaattt atatcagtct
      541 gtacttttaa tgaaccagta gtgtttagtt ctatggaaga ccaagatgaa aaagtacctg
      601 taaatttggc tttcgtatta ggacttaatc aaccacacag tcaattatct gtattaacag
      661 aattaatggg aattatgcaa aataaagagt tagttgataa gttgatgagt tctactgata
      721 aagaagaagt tttaaagaca ctaaagtctt tataaaaata aaaaagtact aaaaataaaa
      781 aatataaaaa taaaaattat taggaggaaa taaaaatgaa aaaaatatta gtagcatgtg
      841 gagcaggaat agcaacatca acagtagttt gtgacaaggt agagagatta gttaaggaaa
      901 ataatataca agcagaagtt atacaatgca aaatagctga atgtgcaaca aagcaagaag
      961 gagcagattt aatagtatca acaactatac taccaacaac ttataatata ccagcaataa
     1021 aagcaacagc atatataact ggagtaaata cagcagcatt agataaaaaa atattagatg
     1081 ctttaaaata atcctatcat agatacattg aaataatatt ttataaaaca gaaaaaggag
     1141 gatttataaa tggataaatt attagcagta gtacaataca ttttaaatat gggaccgaca
     1201 gtaatactac caataacaat tgtagtacta ggaatgatat ttagaattaa gtttacaaaa
     1261 gctttaaagt caggtcttac aattggtata ggatttgtgg gtataaactt agttgtaaac
     1321 ctattaacat caacactagg gccagcggct caaggaatgg ttgaaagatt cggacttaat
     1381 ttaacagtaa tagatgttgg ttggccaaca acagcatcag caacatgggc ttcaccagtt
     1441 gcaccaatat taataccagt ttgtttatta gtaaacttac tattattata cttcaataaa
     1501 acaaagatat taaacgttga tatatggaat tattggcact ttatagtagc aggtgcagtt
     1561 ggatatatag taacaggaag ttatgtttgg gctatattct gtgcaatact aatggagtta
     1621 ttagtactgt ttattgcaga aaagacagca aaaaatgttc aggagtttta tgatttagaa
     1681 ggtatagcat taccaactgg ttcaacagct tcatttgctc cacttggata tttagtaggt
     1741 aaatttgttg aaaaaatacc aggaataaat aaaatacaag cagacccaga ctctatacaa
     1801 aaaagatttg gtatatttgg agaaccaatg atgatgggga ttatactagg tataatactt
     1861 ggagcacttg cgggatatga tgtagcagga atattcaatg taggtatatc aatgggtgca
     1921 gtaatgttac ttatgcctag aatggttaga atattaatgg aaggtttaat tccaatttca
     1981 gaatcaataa gagatttctt acaagcaaaa tatggagaca gagaacttta tataggtctg
     2041 gatgcagcag tagcaactgg acatccagca gttatatcaa cagctcttat acttgttcct
     2101 ataactttgt tcttagcagt tatactacca ggaaacaaag ttttaccatt tggagactta
     2161 gcgacaatac cattttatat ggcatttata gtgtgtttta gaaaaggtaa tatagttcaa
     2221 tcagttataa caggaacaat agtaatagct atatcacttt atatggctac aaactttgca
     2281 gatgttcata cacaattatt acaacaagca aatatgatgc cagaaggaac aacaatggtt
     2341 acaagtatag atacaggtgg aaacttgcta aaatggggaa tattgaaatt atctcaatta
     2401 gtttcttcat ttggaatatt ctagtatgta gttaatagag attactcttt tttagtaaag
     2461 tatgcgaaaa tttaacattt agcagctact aaaaaagagt aatatttttt ataaattttt
     2521 aaaaatacaa aatacaagag gaggagattt atcgtgaaag cagcagtatt acatggcaca
     2581 aatgatatga gatttgaaga tatagaaata aaaccatgtg aaagtgatga agtaaaaata
     2641 aaagttatgg cagcaggaat atgtgggtca gatcctccaa gagtattaaa acattggaaa
     2701 tatccagttc cagctatacc aggacatgag ttttctggag taattgctga agttggtaag
     2761 gatgtaaaaa atgtaaaagt tggagataga gtagttgcaa ttccttttat accttgtaat
     2821 gaatgtgaat attgtaaaag aggattattt tcattgtgtg atgaccatgg aatgttagga
     2881 gctaaaagtt ttggagcttt tgcagagtat gtaaatataa aagctacaaa tgtacttcca
     2941 ataggagata tgaactttga agatgctgca atgatagagc cactagcagt tgctatgcat
     3001 ggagtactta atataggtgt tcaagttgga gacactgtag ctgtaatggg tagtggaaca
     3061 atggggcagt tggtaataca aggacttaaa atagcagggg caggaacaat tatagcagtt
     3121 gatatatctg ataataaatt aagagaatca aaggaattag gggctgatat aataattaat
     3181 gctaaagata ttaacccagt agaaaaaata aaagaactta ctggtggaaa aggtgttgac
     3241 atagctcttg aatgtgcagg ttcaaaaata actcaagaac aatgtttact tataactaaa
     3301 aagaaaagta agataggatt tttagggata gcatattcag atataacttt atcagaagaa
     3361 gcatttgaaa atatatttag aaaagaacta gaattaaaag gtttttggaa ctcttattct
     3421 gcaccatttc caggacaaga atggactaag ggaatcaatc tagttaatga aggaaagata
     3481 aaattaaaag aaatggtatc tcatagattc tcacttgaag atacttacaa agcatttgaa
     3541 atgataagag atagaaaaga agaatttaac aaaatattaa ttttaccaca aggggttgaa
     3601 aaataatgaa agcagtagtt aaaactaaac caggctatga taatgtagaa gttttagaag
     3661 tagaagaacc aaaagctaca ggagacaagg ttaaaataaa agtagaatat agtggtatat
     3721 gtggttcaga tatacattca tttaaaggtg aatatgcaaa tataaaagcc ccagtaacat
     3781 taggtcatga attttctgga attgttgtag aagtaggaga agatgttaaa aatataaaag
     3841 taggggatag agttacatca gagactactt ttgcaacttg tgagaaatgt atatattgtg
     3901 aaactaaaga ttataactta tgcccaacta gaaaaggtat tggtactcaa gtaaatggaa
     3961 gttttgctga gtatgtatta tcaagagaag aaagcataca tgtacttcct gaaaatgtat
     4021 ctttattatc agcagccctt acagagccac tagcttgttg tgttcatgca gctcttgaaa
     4081 agactactat agaaagttct gatacagttt taataatagg accaggacca attggtttat
     4141 tattagctca agttgttaaa tctcaaggtg ctacagttat aatgtctggt gttacaaaag
     4201 ataaggaaag attagaaata gctaaaaatc ttggagtaga tagaactgta aatgtaatgg
     4261 aagaaagttt ggcagatgta gtgaatgaaa tgactgatgg aaatggagta aacaaaggat
     4321 ttgattgttc tgggtttatg ccagcagtta acgaagcctt aagactgctt agaaaaaaag
     4381 gtactttcgt acaagttgga atctttgcta aaaaattaaa tgaaatggac caagaagcaa
     4441 taatccaaag agagttacaa tatataggaa gcaggtctca aaagccaagt tcttggatta
     4501 cagcattaga tttaatggca aatgggaaag taaatacaga agctttagtt actagaactg
     4561 ttggtttaga cgaatttaaa gaaggtatta cagctttaat gaacggggaa gaaataaaag
     4621 tagcagtaaa atcttaaaaa aacatttgta ttattttaaa aaaaattgta aaatctactg
     4681 taggataaaa aaatgtaagg tcttaaaaaa taacaggagg aagaaagtat gagcactctt
     4741 agagatcatt ctaataatat tagaaaaaac ataataaaaa tggttgcaga agctaaaagc
     4801 ggacatccag gtggttcatt atcaatagct gatatgttga cagtattata ttttgataag
     4861 atgaacgtat gtgcagaaaa tccaaaaatg gctgatagag atagatttgt tctatcaaaa
     4921 ggtcatgcag caccagcttt atatgctaca ttagcagaaa aaggattttt cccagaagaa
     4981 gaattaataa cactaagaaa atttggttct aagttacaag gtcacccaga catgaaaaaa
     5041 gtagcaggaa tcgatatgtc tactggttct cttggtcaag ggctatctgc agcaaatggt
     5101 atggcacttg caggaaaatt agataacaaa gactatacag tatatactat attaggtgat
     5161 ggagaaatcc aagaaggtca aatatgggaa gctgcaatga cagcatcaca ttacaaatta
     5221 gataatttaa ttgcatttgt tgacttaaat ggattacaaa tagatggttc taatgaagaa
     5281 gtaatgaatg taagtccagt agatgacaaa ttcaaatctt ttggatggaa tgtaatagta
     5341 ataaatggac attcttttga agaaatagga aatgcagttg atgaagctaa aaaagttaca
     5401 ggaaaaccaa ctgtaataat agctaaaaca gtaaaaggta aaggtgtttc atttatggaa
     5461 aataatgctg catggcatgg aacagctcca aatgcagaac aagcagagca agcattgaaa
     5521 gatttagaag gaggtctata ggaatgggaa tagcaactag agaagcttac ggacaagtgt
     5581 taaaagaact tgcagaaaat aaagatatag tagtattaga tgcagattta ggaaaagcta
     5641 caaaaagtat atcatttaaa gaagttgccc cagatagatt ttttgacatg gggatagcag
     5701 aaggtgacat gattggtaca gcagcaggtc ttgctacttg tggaaaaata ccttttgcga
     5761 gtacttttgc aatatttgca gcaggaagag gctatgagca aataagaaac tctgtagcat
     5821 atccaaattt aaatgtaaaa atagcagcta ctcatgcagg tgtaacagta ggtgaagatg
     5881 gtggtagcca tcaagctata gaggatatat ctctaatgag aggtatacca aatatggttg
     5941 tattaaatcc agcagatgct ttagaagcaa gacaagctat tcttacatct attgattata
     6001 atggacctgt ttatataaga ttaggtagag ctgcaactcc tgatgtaaac agtgaaaatt
     6061 ataaatttga aataggaaaa ggaactgttt taagagaagg ttctgacata acagtaatag
     6121 ctacaggaat aatggtagca aaagccttag aagcagcaga agaacttgct aaagaaggta
     6181 taaatgtaga agttgttaat atatctacaa taaaaccatt agatgaagca ttaataaaag
     6241 aaactgctaa gaaaactgga aaagtagtta cagcagagga gcacagtata ataggtggtt
     6301 taggttcagc tgtatgtgaa gctttagcag aaactaaaga tgtagtagtt agaagaattg
     6361 gtgttaaaga tgtatttggt caatcaggta caccagctga tttattaaaa cactatggtt
     6421 taactacaga agatatagta aaaaatataa aagagttgtt atagatataa atatatctaa
     6481 ataacaaatt gatttgacat aagtcaatta aagctgtctt aaaaatagaa agaaatttct
     6541 acaatgggac agctttattt ttacaatact ttatttttat gataattata aaatagtctg
     6601 aaagtaatca aaaaaattat aaaaagaggt gctatttaat gaaaatatct attggatgtg
     6661 accatggtgg ttatgaatta aaggaatata taaaggaaaa tttaataaat aaaggtatag
     6721 aagttgaaga tgtgggtaca aattcaaaag aaagtgtaga ttttccaata tatgcaaaaa
     6781 aggtaagtca aaatgttcaa agtaaaaaat ctgatttagg catactttgt tgtggaacag
     6841 gaataggtat gtctattgca gcaaataagt ttaaaggaat cagagcagct gttgtttctg
     6901 actgtttttc agctaaggca actagagaac acaataatac aaatgtactt tgtttaggag
     6961 aaagagttat tgggaaagga ttagcaatga gaattgttga agaatggtta aattcaagtt
     7021 ataatggaga aagacatgca agaagattac aaatgattga tgatatagaa aaagaaaatt
     7081 tataaatata taatttacaa caagggggag cgttatgtct attatttgtg cttcaataat
     7141 gtgtgcagac caaatgaagt taaaagagga attagaagct cttgaagaag caggtgtaaa
     7201 attacttcat tgtgatgtta tggatggaat atttgttaaa aacttggcta tgggaccaga
     7261 gttattaaaa tcaataagtg aaaatacaac aataccttta gacatacact tagccacaga
     7321 aactccagat aaatatattg atatgatgtc ttatataaag ccaaaatata tttcttttca
     7381 tgtagaatca agtacaaatg taaaagctga tatacaaaag ttaagaaatt atggtatagg
     7441 gccagtgtta gcaataagcc ctcaaacaag tgtggataaa atagaagaat atataagttt
     7501 agttgagggt atcttagtaa tgacagtaaa tccagggttt gcaggtcaaa agtttaatct
     7561 ttctgtattg gataagttgg ataaacttac agagatacta aaagattatg ataatcctcc
     7621 atttatagag gttgatggaa atataaataa ggatactatt aaacttatga atggtaaaaa
     7681 agtagatata tatgttgttg gtacttcagc tttatttaat gataagcctc caatttcata
     7741 taaagataaa atagaagaac taaaagaaag tataaagtaa ccatgtaata aaattataat
     7801 atgtttctgt ttaatagtaa aaatttaggt ggaaacaaga aattttataa tatttaataa
     7861 aaattttggt tgagtaagga gaatttttta tgggagacct atataaacta caaaatggta
     7921 ctgatattag aggaatagcg tatgaaaatg attctaaaga agttaaccta actgtagaag
     7981 aagtaaaaaa aatagctaaa gcgtttcata tttggttaaa agaaaagact aagaaagata
     8041 aagtaactgt tgccatagga actgattcta ggataacagg aagccaattt agaagtactg
     8101 ttattgaaac tttaactaat gatgattgta atgtaattga ttgtgagatt gccacaactc
     8161 cagctatgtt tatgacaact attatggatg gatacaattc tgatggggcg attatgatta
     8221 cagcaagtca cttaccttat tactataatg gtttaaagtt tttcacagaa agtggaggtt
     8281 tagaaaaaac tgatataaaa gagatgttgg atatagctgt taaaaatgat agtgtagact
     8341 atgaggaagt aaataaaaaa ggtgaagtta tagtaaaaaa tttaatagaa gattattcta
     8401 atttattgat agataaaatt agaaaaggtg taaattcaag taaaaattat gaaaagcctt
     8461 tttctgggct taagatattg gttgatgcag gaaatggggc tggtggattc tttgctgaaa
     8521 aagttttaca catactggga gcagatacga caggtagtca gtttttgaac ccagatggta
     8581 tgttcccaaa tcatatacct aatcccgaaa acaaagaagc aatggaaagc atatgtaaag
     8641 ctgtgttgga taataagagc gacctaggaa taatctttga tacagatgta gacagagctg
     8701 ctattgtagg taaaaatggc aaaccaataa ataaaaatgc tcttatagct gttatatcat
     8761 caatagtatt agaagaacat ccaaaaacag ctatagtaac agattcgatt acttctgaag
     8821 gacttgctaa atttataaat gaattacaag gaagacatca tagatttaaa agaggatata
     8881 aaaatgtaat aaatgaagct ataagattaa atagtgaagg tgaagagtgc catttagcta
     8941 tagaaacgtc tggacatgct gctttaaaag aaaattattt cttagatgat ggggcatatt
     9001 taatagctaa aattttaata aaagtagcaa agctatcctt ggaaggaaag actatagaag
     9061 aattgataga aaaccttgaa gaagctcaag aagagaaaga agttagaata ggcattaata
     9121 aagaagattt tagaacatat gcagaggata tattaaaaga tttagattct catgttaaga
     9181 gtattgatgg atggtctgta gcaccaaata attttgaagg cataagagtt aattgtgatg
     9241 aatcaaatgg agatggatgg tttttactta gaatatcact acatgaacca ttattagctt
     9301 taaatattga atcaaataaa attggcggag cagaacaaat ttattctaag ttaaaacttt
     9361 tcttagaaaa atatgattta aaaggtcttt agggtaaata gaaagaatat atttatattg
     9421 aagaataaat gtaaatttgt acctaagatt acaaatatta caaaattgta atcttaggta
     9481 acagagatgt aactgattat ggaaacacta tgtgatatta tagatacaga gagatgaaat
     9541 atgtgatgaa ttatagagaa atataattta aaatgtatta atatcacacc aaaaaggtat
     9601 aatcaaaaaa tatgtaaata taaaccccaa catttagaaa aagacctcta aggaggtttt
     9661 tttcttgttt aaataactta aaatatattt ttatattaat atatcaatta acttttctaa
     9721 aagtaagcat taccttaaat aaatcagcat ctataattat ttccatgtgt gcattttcta
     9781 attcaattat attttgagca attgataaac caagaccaga gccatctgtt tttctagata
     9841 tatcacccct tctaaatctt tctattaact cttctggttt tagatttagt ttatcatttg
     9901 aaatattttt aaacgttaat attatatttt cttcctttat aaacatatct atatagaccc
     9961 tagtgttagg catagagtat tttagtatat tgcaaattag attctcaaaa actctccaag
    10021 tttttttacc atctatcatg gtaaaaacag catattcagg tgtttctatt ataaaatcta
    10081 aactgctatt ttgaattttg tcttcaaatt ctacaatact ttgaattaaa agttctctta
    10141 tatcggtttt tgttatatta aattctacat ctccactact tagcttagat gcttcaaata
    10201 tgtcatctat taataatttt aatctttgtg attttttatc taaaatattt atatagtcat
    10261 ttatagtctc tctgtcaaag tcattatttt ttaacatatc aacatagctt aatatagatg
    10321 taagtggagt ttttaagtca tgagatacgt ttgtgataag ctctgccttc atcctttcat
    10381 tttttatatt agcatctaca gcagtttcaa gaccgcctgt tatattattt atacttttgg
    10441 ctaaagtaga tatttcatca tctcctataa cttctaattt atactttaaa ttgccatttt
    10501 ctatattttt tatatttttt gatatgttat ttatgtaatt aaacttaaca gataaaaagt
    10561 tgtatatata aaaatgaaaa actgtgttta caagtgtaaa taaaattact atagctattg
    10621 cctcagcata atatatatac ataaagaata tcaaaacaag atattggata atagcttgta
    10681 caactataga tattaaaaat actatagcta attttttatt tatagttttt ttattataca
    10741 tactaagtaa gtttgaaaag aatacatatg ttatagacat atcttttaga ttatagtt
//
LOCUS       DAMJVG010000107        10785 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.112, whole genome shotgun sequence.
ACCESSION   DAMJVG010000107 DAMJVG010000000
VERSION     DAMJVG010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10785)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10785)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10785
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.112"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            66..833
                     /locus_tag="PC512_003303"
     CDS             66..833
                     /locus_tag="PC512_003303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YoaP domain-containing protein"
                     /protein_id="HDF2443023.1"
                     /translation="MQIIDININNIDNEHICCSISEKKGENCVFSKKAWMKNNFDKGL
                     VFKRFDVRGKAFIEYIPAENAWCPITADNYIFINCFWISGKFKGQGYSNLLLQECVDD
                     AKSKGKYGLVVLSSSKKMPFLSDAKYLKYKDFCLADTSEPNYELLYFPFTDNAPIPCF
                     KNCVKQRKLNENGIVLYYSNQCPHTEKYAPILKKIANSRGIDVNLIKFETAKEAQNAP
                     APFTTYSLFFNGEFVTNEILSEKKIEKFLDTNIKKFN"
     misc_binding    1051..1264
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1518..2552
                     /locus_tag="PC512_003304"
     CDS             1518..2552
                     /locus_tag="PC512_003304"
                     /EC_number="1.2.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyl-gamma-glutamyl-phosphate reductase"
                     /protein_id="HDF2443024.1"
                     /translation="MNKIKVGIIGATGYVGAELIRLLMNHDKVEVTAIGSNSYVGKDI
                     VDIYPSIGYKNNMICIENEKVIDMCDVVFTALPHGVSEKFVIKAIKSKKKVIDLGADF
                     RIKDEEVYSKWYGVSFIDKILHKKAVYGLSEIYKEDIKDADIIANPGCYPTSISLPLM
                     PLLSSKLIKNNNIIIDSKSGLTGAGRELSISSHFTEVNENITAYKIGKHRHTPEIEQN
                     LSESCKEKVSVVFTPNLIPVNRGILSTIYCTKEDNISINDIHRKLTDYYEFKEFIEIL
                     PLDKIASLKNVRFSNKCVISLHENGDTLIICSAIDNMIKGAAGQAIQNMNIIFGIEEN
                     TGLKNIAPSF"
     gene            2593..3810
                     /gene="argJ"
                     /locus_tag="PC512_003305"
     CDS             2593..3810
                     /gene="argJ"
                     /locus_tag="PC512_003305"
                     /EC_number="2.3.1.1"
                     /EC_number="2.3.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate
                     N-acetyltransferase/amino-acid acetyltransferase ArgJ"
                     /protein_id="HDF2443025.1"
                     /translation="MEIIKGGVTVSEGFFASGIHCGLRKNKEKRDLALVYSDVLCDAA
                     AVVTQNKVKGNPVYVTQEHIKNGKAQAIIVNSANANTFNGKEGLINAYKMAKFTSDKL
                     NIKESDVLVASTGVIGKPLNIDLIEENMDELVNNLSKQGHIGAREAIMTTDIIKKEIA
                     VAIMYGDKKITIGGMAKGSGMIHPNMATTLGFITTDANIDGVLLKEALKIAVDKSFNR
                     VSVDGDTSTNDMVMILANGKAKNDRINKKDEHYQVFLSALTYVCIELAKLVAKDGEGC
                     TKLIECYINGALSEAHAVKLAKTVISSSLVKTAVFGADANWGRILCALGYAGEEIDME
                     KVDIIFESMKGYIEVCKNGNGLDFNEEKAKKILEDDEISILVDLNMGNARGNAWGCDL
                     SYDYVRINGSYRN"
     gene            3825..4685
                     /gene="argB"
                     /locus_tag="PC512_003306"
     CDS             3825..4685
                     /gene="argB"
                     /locus_tag="PC512_003306"
                     /EC_number="2.7.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylglutamate kinase"
                     /protein_id="HDF2443026.1"
                     /translation="MINIEKANTLIEALPYIEKHQGKTIVVKYGGSAMKKDGLKESVM
                     EDLVLMSYVGINIVLVHGGGAEINKMLAKVDIESKFVNGLRYTDEETMEIVKMVLAGK
                     VNKDLVNKIHTKGGKAVGLCGIDNNMILCDPYKNYELGFVGEIKKVNVELIESCLKSG
                     YISVIATIGVGDDGETYNINGDTAASAIAKELNADKLILLTDVPGLLREPDEEKSLIT
                     EVILEDVDKLFEEGIITGGMIPKIEGCVDALNNGVNRVHILDGRVPHSIITELFTDSG
                     IGTLIRKENE"
     gene            4715..5902
                     /locus_tag="PC512_003307"
     CDS             4715..5902
                     /locus_tag="PC512_003307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate aminotransferase family protein"
                     /protein_id="HDF2443027.1"
                     /translation="MNNDNTISKWNEYFIDTYNQPNFVIDYGEGSCFFDTNGNKYIDF
                     TSGYGVSSLGYSNSNLKNALKEQVDKLLHTSNLYFNEPVLYSGEKIINSSGMAKVYFC
                     NSGTEANETAFKIARKYSSDKYGNGRGTIISLKDSFHGRTMMSLMATGMDKYHKYFYP
                     LPEGFKYVERNNIEDLKNNLDSTVCAIILEAIQGEGGVNVLEKDYVLEIVKICQEKDI
                     VVIFDEVQCGIGRTGKLFGYEYFDVKPDIVTVAKGLGAGIPVGGVLVNKKLSKVLGKG
                     DQGTTFGGNLLAMVAASVVLDEISKDGFYNEVLEKGNYIRKSIESFNNKVVLKTKGIG
                     LMIGIETNIESSIIEEKARKKGLLILTAGKNVLRFLPPLTISYKEIDEALEILKDILL
                     EIN"
     gene            6011..7033
                     /gene="argF"
                     /locus_tag="PC512_003308"
     CDS             6011..7033
                     /gene="argF"
                     /locus_tag="PC512_003308"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HDF2443028.1"
                     /translation="MNNISLKGKSFLTLKDFTKEEIRYLLTLSSYLKTKKKVGIKGDL
                     LQGKNIALLFEKTSTRTRCSFEVAAHDEGAHVTYLGPNDCHMGKKESVSDTAKVLGRF
                     YDGIEFRGFKQETVESLAKYSGVPVWNGLTDEYHPTQILADFLTVIENVDKDLNKVKF
                     VYVGDARNNMGNSLMIGCAKMGIHFVALAPKELWPNEELVKEMKEIAKKSKGDIMLTE
                     NIDDVKGADVIYTDVWVSMGEEEQYEARINQLKDYQVNMDMIKKTENENVIFLHCLPA
                     FHDLETKVAQEIYEKFGLSELEVTNEVFNSKYSKVFEEAENRMHTIKAVMVSTMTDVN
                     MNNNLI"
     gene            7160..7777
                     /locus_tag="PC512_003309"
     CDS             7160..7777
                     /locus_tag="PC512_003309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4878 domain-containing protein"
                     /protein_id="HDF2443029.1"
                     /translation="MKKIILALTTFLLAISLTACSSAKPEDTIDSFFNSAKKFDFEGM
                     NKVMENNDEKYKDILKELDTKDPNAQYVLDYLKQNASKITYTIKDSEVKGDKATIKVE
                     CKFIDSTPLLQEIVAEAFTKMIGMSFSGQDLTDEKTTEMLVSIMKEKQKSVKETYVTK
                     NVEFECSKKDNKWIISSVNDAVADVLLSNLVTAGQEFSNSMNTLE"
     gene            complement(7997..8695)
                     /locus_tag="PC512_003310"
     CDS             complement(7997..8695)
                     /locus_tag="PC512_003310"
                     /EC_number="5.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid racemase"
                     /protein_id="HDF2443030.1"
                     /translation="MNEKLIGILAGMGPRSTAPFVDLIIDECQSQYGAKYDDEFPKMM
                     IYSLPTPFYIDRPINHELMKETIIDGLQKLESTGVNFIAMPCNSAHIYFKELKESINI
                     PILNIVEETVKKLPTISQKVTLFSTSSTFESTIYQNGIIHNGHEFIFKDEWQIKLNNL
                     IQNIKMDKENPHNIDIWNKLIEDVKNESIENIVIACTDLNVVLEKSYPSINIVDSSKC
                     LAESVVNKYLKLVK"
     gene            complement(8857..10074)
                     /locus_tag="PC512_003311"
     CDS             complement(8857..10074)
                     /locus_tag="PC512_003311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallo-hydrolase"
                     /protein_id="HDF2443031.1"
                     /translation="MLGKKCMDYLQTLGKISSTTNGLTRLILTQEHKKSIDLISSWME
                     GLNLDIEIDDIGNVIGTYKSSFPNAPTLVVASHQDSVKCGGIFDGMLGIIVPLVGLEE
                     AKHNNRSYPFNIKLIAFAEEEGTRFETSLMGSKVFAGTFKEELLKSVDENGITLEEAV
                     TKFGFNTKNLTNLHPRKDVDAYLEFHIEQGPVLENESLPAGIVSSITGFKSFKISVNG
                     KSGHAGTLPMNMRLDAGCCACECVLAIEKVAKTTADLVATVGKMNFYPSSSNVVPERA
                     EFTLDVRSCSQEILDNSVEKIFNEISHICENRKLNYTSELAFENVPVPCSNKITKIIE
                     KSFIDLNLNPFYIYSGAGHDAQEMDNITDIGMVFIRCAGGVSHNPNESVSVDDLDTAV
                     KIFLKILDNLDLK"
     gene            complement(10265..10678)
                     /locus_tag="PC512_003312"
     CDS             complement(10265..10678)
                     /locus_tag="PC512_003312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2443032.1"
                     /translation="MELEITEKIEKQDEDTIFQGLLKYNLARLEDKNPVDLGIYIRDK
                     AGKIVAGFIGVTHGNWLSIKYLWVSEKLRYKGTGSQLLYKAEKIAKERGCKYVFLDTF
                     SFQAPKFYEKFGYHKVFSLENYPLTGKRYYFRKIL"
BASE COUNT         4220 a         1180 c         1805 g         3580 t
ORIGIN      
        1 atattaagat aaaaatatat agaatatatt taaaaattat tatgcaatta gaaaaggaga
       61 taagtatgca gattattgat ataaatataa ataatattga caatgaacat atatgttgtt
      121 caatttctga aaaaaaagga gaaaattgtg ttttttctaa aaaagcttgg atgaaaaata
      181 attttgataa aggtctagtc tttaaacgat ttgatgtaag aggtaaagct tttatagaat
      241 atattccagc agaaaatgca tggtgtccta ttactgcgga caattatata tttattaact
      301 gtttttggat atctggaaaa tttaagggtc aaggatattc taatctattg ctacaagagt
      361 gtgttgatga tgcaaaatca aaaggtaaat atggattagt tgtgctttcg tctagtaaaa
      421 aaatgccttt tttatctgat gctaaatatc taaaatataa ggacttttgt ttagcagata
      481 catcagaacc aaattatgag ctattatatt ttccctttac tgataatgct cctattccat
      541 gttttaagaa ttgtgtaaaa caaagaaaat taaatgagaa tggtatagtt ttatattaca
      601 gtaatcagtg tccacatacg gaaaaatatg ctcctatttt gaaaaaaatt gcaaattcta
      661 gaggtattga tgtaaatctt ataaaattcg aaacagcaaa agaagcacaa aatgctcctg
      721 caccatttac tacatacagt ctttttttta atggtgaatt tgtaaccaac gagatacttt
      781 ctgagaaaaa gattgagaaa tttttagata ccaacattaa aaaatttaat taaaaagaga
      841 tgtaaatatt gtattttgaa aatatattat tttataattt aatatatttt ggatgttttt
      901 taaattgacg aatgaaatat aaaaattata tcgcaattta gatacaaaat gctggaaatt
      961 aaccatatag aaaatatttc caaaaattta aaaattatat tgacaaagtt aaaaaaataa
     1021 actatcatat aaaacaataa gaaaataaat tgaaatcctg tgaaaaagag agtagcataa
     1081 agctagttga tagagagctg ggaatggtgg aagcctagta acgaatttta ttgtgaatag
     1141 agctttggag gagattacca gaagtaatag tatggtaatt ggtgaatctc gccttaagag
     1201 attagagtgg gtaagattat cttatcaatt agagtggtaa cgcgggtgta tattcgtctc
     1261 ttggtctttg accaagaggc ttttttaatt ttaaatgtac attttgtaga tactttttaa
     1321 tttgagtttt aatgattatt gtaattttac caataagagt ggtaccgcgg aaaatcgcct
     1381 cttagtattt ataatgctaa ggggtttttt gttttaatta gagtatttta atctacgtat
     1441 tatcaaatga ttatcatata gtaaagtgga aagataggat tttaagacta tttgaatata
     1501 aaaatggagg gaacaaaatg aataaaataa aagttggtat tattggtgca actggatatg
     1561 tcggggcaga gttgattaga ttattaatga atcatgataa agtcgaagtg acagcgatag
     1621 gttcaaattc gtatgttgga aaagatatag ttgatatata tccaagtata ggatataaaa
     1681 ataacatgat atgtatagaa aatgaaaaag ttatagatat gtgtgatgtt gtgtttacag
     1741 cccttccaca tggagttagt gaaaagtttg taataaaggc aattaaatcg aaaaagaaag
     1801 ttatagattt aggtgctgac tttagaataa aagatgaaga agtatatagt aaatggtatg
     1861 gagtatcttt tatagataaa atcttacata aaaaagctgt atatggatta agtgaaatat
     1921 acaaagaaga tataaaagat gcagatataa ttgcaaatcc tggatgttat ccaactagta
     1981 tttctttacc attgatgcca ttactaagtt ctaaattgat aaaaaataat aatataataa
     2041 ttgattctaa atcaggtctt acaggtgctg gtagagaatt atcgattagt agtcacttta
     2101 cggaggttaa tgaaaatatc actgcatata aaatagggaa acacagacat actccagaaa
     2161 tagaacaaaa tttaagtgaa tcctgcaaag aaaaagtaag tgtagttttt acaccaaact
     2221 taatcccagt aaatagggga atcttatcaa ctatatattg tacaaaagaa gataatattt
     2281 ctataaatga tatacatagg aaattaactg attattatga atttaaagaa tttatagaaa
     2341 ttcttccatt agataagata gcttctttaa agaatgttag attctcaaat aaatgtgtaa
     2401 tatcattaca tgaaaatgga gatacattga taatctgttc agctatagat aatatgatta
     2461 agggagcagc aggtcaagct atacaaaaca tgaatataat atttggtatt gaagaaaata
     2521 caggtttaaa aaatattgca ccatcatttt agaaataaaa aatactaaac tcatataatt
     2581 aggaggataa atatggagat tataaagggt ggagttacag tttcagaagg attttttgct
     2641 tcagggattc actgtggctt gagaaaaaat aaagaaaaaa gagatttagc tttggtttat
     2701 tcagatgttt tatgtgatgc agcagcagta gtaactcaaa ataaagtaaa gggcaatcct
     2761 gtttatgtta cacaggaaca cattaaaaat ggaaaagcac aagctatcat agtaaatagt
     2821 gctaatgcta atacctttaa tggaaaagaa ggacttataa atgcttataa aatggctaaa
     2881 ttcaccagtg ataaattaaa tattaaagaa agtgatgttt tggttgcatc tacaggtgtt
     2941 ataggaaagc cattaaatat agatttaata gaagaaaata tggatgaatt agtgaataat
     3001 ctaagtaaac aaggtcatat tggagcaaga gaagctatta tgacaactga tattataaaa
     3061 aaagaaatag cagtagcaat aatgtatgga gataaaaaaa taactattgg aggtatggca
     3121 aaaggttctg gtatgataca tcctaatatg gcaacaacgt taggatttat aactacagat
     3181 gcaaatattg atggagtttt gctaaaagaa gctttaaaaa ttgctgttga caaaagtttt
     3241 aatagagtta gtgtagatgg agatacaagt actaatgata tggtaatgat tctagcaaat
     3301 ggaaaagcaa aaaatgatag aataaacaaa aaagatgaac attatcaagt atttttgagt
     3361 gcacttacat atgtctgtat agaacttgct aaacttgttg caaaagatgg agaaggatgt
     3421 acaaaactaa ttgaatgcta tataaatgga gcattaagtg aagcacatgc agtaaaatta
     3481 gcaaaaacag ttatatcttc ttcattagta aagacagctg tatttggagc tgacgcaaat
     3541 tggggtagaa tactgtgtgc tttaggttat gcaggtgaag aaatagatat ggaaaaagtt
     3601 gatattattt ttgagagtat gaaaggatat attgaagtat gtaaaaatgg aaatggatta
     3661 gattttaatg aggaaaaagc aaaaaaaatc cttgaagatg acgaaataag tatattagta
     3721 gatttaaata tgggcaatgc cagaggaaat gcatggggat gtgatttaag ctatgattat
     3781 gtaagaataa atggaagtta tagaaattag gaggatatac tttaatgatt aatatagaaa
     3841 aagcaaatac acttatagaa gctttaccat atatagaaaa acatcaggga aagactattg
     3901 tagttaagta tggtggaagt gcaatgaaaa aagatggtct aaaagaatct gttatggaag
     3961 accttgtgtt aatgagttat gttggaatca atatagtttt agtacatggt ggaggggcag
     4021 aaatcaataa gatgctagca aaagtggata tagaaagtaa atttgtaaat ggtcttagat
     4081 atacagatga agagaccatg gaaattgtaa aaatggtact tgctggaaag gttaataaag
     4141 acctagtaaa taaaatacat acaaaaggtg gaaaagcagt agggctttgt ggaatagata
     4201 ataatatgat tttatgtgac ccatataaaa attatgaact tggatttgta ggagaaatca
     4261 aaaaagtaaa tgttgagctt atagaatctt gtctaaagtc aggttatatt tcagtaattg
     4321 caactatagg tgttggagat gatggagaga cttataatat aaatggtgac acagcagctt
     4381 ctgctatagc taaagagtta aatgcagata aattgatact tcttacagat gtccctggtt
     4441 tgttaagaga gccagatgaa gaaaaatcat taataacaga agttatatta gaggatgttg
     4501 ataaattatt tgaagaaggt ataattactg gaggtatgat acctaaaata gagggatgcg
     4561 tagatgcctt aaataacgga gtaaataggg tacatatttt ggatggaaga gttccacatt
     4621 ctataataac agagctattt actgatagtg gaataggtac attaataaga aaagaaaatg
     4681 aataaaatta taagtttaag aggggagaat aagaatgaat aacgacaata caatttcaaa
     4741 atggaatgaa tattttatag atacatataa tcaacccaat tttgtcatag attatggtga
     4801 aggaagttgt ttttttgata ctaatggcaa taaatatata gattttacaa gtggatatgg
     4861 agtatcttct cttgggtata gtaatagtaa tttaaagaat gctctaaaag agcaagtaga
     4921 taaattatta catacttcaa atttatattt taatgagcca gtgttgtatt caggagagaa
     4981 aataattaat tcaagtggaa tggctaaagt atatttttgt aattctggaa cagaagcaaa
     5041 tgaaacagca ttcaaaatag caagaaagta tagtagtgac aaatatggta atggtagagg
     5101 aactatcata agtttaaaag actcttttca tggtagaaca atgatgtctt taatggcaac
     5161 tggtatggac aaataccata agtattttta tcctcttccc gaaggtttta aatatgtaga
     5221 aagaaataat attgaagatt taaaaaataa tcttgattcc acagtttgtg caataattct
     5281 tgaagcgatt caaggcgaag gtggagttaa tgttcttgaa aaagattatg ttttggaaat
     5341 agtaaaaata tgtcaagaaa aggatattgt agtgattttt gatgaagtcc aatgcggtat
     5401 aggaagaact ggtaaacttt ttggctatga atattttgat gtaaaaccag atatagttac
     5461 cgtagcaaaa gggttgggag caggaatacc agtaggagga gtattagtaa ataaaaaact
     5521 ttcaaaagta ctaggaaaag gagaccaagg tacaactttt ggaggtaatt tattagctat
     5581 ggtggcagct tcagttgtat tagatgagat atctaaagat ggtttttata atgaagtatt
     5641 agaaaaagga aattatataa gaaaatctat tgaaagtttt aataacaaag ttgtattaaa
     5701 gacaaaaggt attggtctaa tgataggaat tgaaactaat attgaatcta gtattataga
     5761 agagaaagct agaaaaaaag gattgcttat tttgactgct ggaaaaaatg tattgagatt
     5821 tttaccacca ttaacaatca gttataagga aatagatgag gctcttgaaa tcctaaaaga
     5881 tatattacta gaaattaact aaatattcaa gaaatagttg attaaagata aaaattagaa
     5941 gtaaataaaa aagtaaagtg ctaacaagtt taattgaatt taaaaagttt ataagaaggg
     6001 gcgaattaat atgaataata taagtttaaa aggtaagagt tttttgacat taaaggattt
     6061 tacaaaagaa gagattagat atttattaac tttatcaagt tatttaaaaa ctaagaaaaa
     6121 agttggtata aaaggcgatt tgctacaagg aaaaaatata gctttattat ttgagaaaac
     6181 atcaacaaga actagatgtt catttgaagt agcagctcat gatgaaggag cacatgtaac
     6241 ttatctaggt ccaaatgatt gtcatatggg taaaaaagag tctgtatcag atacagcaaa
     6301 agttctagga agattctatg atggaataga atttagaggc tttaaacaag aaacagttga
     6361 aagtctagca aaatattctg gtgtgcctgt ttggaatgga cttacagatg aatatcatcc
     6421 aacacaaata ctggcagatt ttttaacagt aattgaaaat gtagataaag atttgaataa
     6481 agttaaattt gtatatgttg gtgatgctag aaataatatg ggaaactcac tgatgatagg
     6541 atgtgctaaa atgggaatac atttcgtagc actagcacct aaggaacttt ggccaaatga
     6601 agaattggtt aaggaaatga aggaaatagc caagaaatcc aaaggagata taatgttgac
     6661 tgaaaatatt gatgatgtta aaggtgcaga tgttatatat acagatgtat gggtttctat
     6721 gggagaagag gagcaatatg aagcaagaat aaatcaactt aaagattatc aagtaaatat
     6781 ggatatgata aagaaaactg aaaatgaaaa tgttatattt ttacactgtc ttccagcatt
     6841 tcatgattta gaaactaagg ttgctcagga gatttatgaa aagttcggat tatcagaatt
     6901 agaggttaca aacgaggtat ttaattcaaa atattcaaag gtatttgaag aagctgaaaa
     6961 tagaatgcat acaataaaag ctgttatggt ttctactatg actgatgtaa atatgaacaa
     7021 taatttaata tagatatgtt ttaatataga ctttacttta atgaaaattt ataaaatatt
     7081 ttaaatatat tattcaaaaa ctctcattat atgttaaaat aacttatgta tcaacaaatt
     7141 aagagggagg atttgagata tgaaaaaaat catattagct ttaacaactt ttttattagc
     7201 aatatcttta acagcatgtt caagtgcaaa accagaagat acaattgata gtttttttaa
     7261 cagtgcgaaa aagtttgact ttgaaggcat gaataaggta atggaaaata atgacgaaaa
     7321 atataaggat atattaaagg aattagatac aaaagaccca aatgcccaat atgttttaga
     7381 ttatctaaaa cagaatgcat ctaaaatcac atatacaata aaagacagcg aggttaaagg
     7441 tgataaggct acaatcaaag tagaatgtaa atttatagat tcaacaccat tacttcaaga
     7501 aatagtagct gaggcattta caaagatgat tggtatgagt ttttcaggac aagacttaac
     7561 tgatgagaaa acaactgaaa tgttagtatc aattatgaaa gaaaaacaaa aaagcgttaa
     7621 agagacttat gttacaaaaa atgtagagtt tgaatgttct aaaaaggata ataaatggat
     7681 aataagttca gtaaatgatg cagtagctga tgtattgtta tctaatcttg ttacagcagg
     7741 acaagaattt tctaactcta tgaatacact tgaataatat tgtttaggtg tagtaaagta
     7801 ataaatatat gattattttt ataaataaac atataaatat ttatgaagga taccattttt
     7861 ggtatccttt ttattaatat aatgaaatac atggttaatt tctatattgt caagaaacta
     7921 tgatatatgt tataagtcta tactatttaa aataaactta taacatatat tttttataat
     7981 atagtgcatg aaaaatttat ttaactaatt ttagatattt attgacaact gattcagcca
     8041 agcattttga tgaatcaaca atatttattg aaggatatga tttttctaaa actacattta
     8101 aatcagtaca agcaattact atattttcta tagattcatt tttaacatct tcgataagtt
     8161 tattccaaat atcaatattg tgtggatttt ctttatccat ttttatattt tgaataagat
     8221 tgtttaattt tatttgccat tcatctttaa atataaattc atgtccatta tgtattatac
     8281 cattctggta aattgtagac tcaaaagttg aactagtcga aaaaagagtt actttttgtg
     8341 agatagtagg taatttttta actgtttctt ctacaatatt taatattggt atattaatag
     8401 actcttttaa ttctttaaag tatatatgtg ctgaattgca tggcattgca ataaaattta
     8461 caccagttga ttcaagcttt tgtaatccat caattatagt ttctttcata agttcatgat
     8521 ttattggacg gtcaatataa aatggggtag gtaatgaata tatcatcatc tttggaaatt
     8581 catcatcata ttttgctcca tattgagatt gacactcatc aataattaaa tcaacaaaag
     8641 gggctgttga ccttggaccc attccagcca aaataccaat taatttttca ttcataaaaa
     8701 ttatctcctt tatatataaa tatatttatg tataaaataa aaatctataa aagcataaaa
     8761 ttatatttta taatagatta tattgtacac ttatataata taaatataaa gtgatttttt
     8821 agattatata ttttaatata ctttcttata taagaattat tttaaatcaa gattatctag
     8881 tatttttaaa aatattttta cagcagtatc caagtcatct acagaaacac tttcattagg
     8941 attatgactt acgcccccag cgcatcttat aaataccata ccaatatcag ttatattatc
     9001 catttcctga gcatcatggc cagcaccact ataaatataa aaaggattaa gatttaaatc
     9061 tataaaactt ttttctatga tttttgttat tttattagaa catggtacag gaacattttc
     9121 aaaagcaagt tcacttgtat aattaagttt tctattttca catatatgtg atatttcatt
     9181 aaatatcttt tctacagaat tatcaagaat ttcttgtgaa caagagcgta catcaagagt
     9241 aaattcagct ctttcaggta ccacatttga tgaagatgga tagaaattca tctttcctac
     9301 agtagcaacc aaatcagcag tcgttttagc tactttttcg atagctaata cacattcaca
     9361 ggcacaacat ccagcatcaa gtctcatatt cattggaagt gtaccagcat gtccagactt
     9421 accatttact gatatcttaa aacttttaaa tcctgtaata cttgatacaa ttccagcagg
     9481 aagagattca ttttctaaaa caggaccctg ctcaatatga aattctaaat atgcatctac
     9541 atcttttcta ggatgcaaat ttgttaagtt ttttgtatta aatccaaact ttgttacagc
     9601 ttcttcaagt gtaattccat tttcatcaac agatttaaga agttcctctt taaaagtacc
     9661 agcaaaaact ttacttccca ttaaagaagt ttcaaatcta gttccttcct cttcagcgaa
     9721 agcaattagc ttaatattga aaggataaga cctattattg tgttttgctt cttcaagacc
     9781 aactagaggc actattatac ctaacatacc atcaaatata cctccacact ttacactatc
     9841 ttgatgagat gcaactacta atgtgggagc atttggaaag cttgatttat atgtacctat
     9901 aacgtttcca atgtcatcaa tttcaatatc aagatttaaa ccttccatcc atgaactaat
     9961 taaatcaata gattttttat gttcttgagt caagataagt cttgtaagac catttgttgt
    10021 tgaacttatt tttcctaatg tttgtagata atccatacat ttttttccta acatatttac
    10081 ctcctaaaaa tataattttt atttaagcta agattagctt ttatacttat aatttttgaa
    10141 ctttcaaata attttgtatg tatagtaaaa tactatttta gtattaataa tgatataaaa
    10201 atataaagtc tgtagacgaa gagcagaagt tttaagttaa aaatataaaa tatgattttt
    10261 attattatag tatttttcta aaataatatc tctttccagt tagaggataa ttttcaagtg
    10321 aaaatacttt atggtatcca aatttctcat aaaatttagg tgcttgaaaa ctgaatgtat
    10381 ctaaaaaaac atatttacaa cctcgttctt tagcaatttt ttcagcctta tataaaagtt
    10441 gacttccagt acctttatat ctaagcttct cactaaccca taagtatttt atagaaagcc
    10501 aattaccatg agtaacacct ataaaacctg caacaatttt acctgcttta tctcgaatat
    10561 atattcctaa atccactggg tttttatctt caagtctagc aagattatat tttaataatc
    10621 cttgaaaaat agtatcttca tcttgttttt ctattttttc tgtaatttct aattccatat
    10681 ttgaactttc tccttgtata atcttttgta tattggtatt ttttaataaa atcagtagaa
    10741 agaatatagt ttaacattat tctaataggc atttatgcta atgtc
//
LOCUS       DAMJVG010000108        10737 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.113, whole genome shotgun sequence.
ACCESSION   DAMJVG010000108 DAMJVG010000000
VERSION     DAMJVG010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10737)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10737)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10737
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.113"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            29..1087
                     /locus_tag="PC512_003313"
     CDS             29..1087
                     /locus_tag="PC512_003313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
                     /protein_id="HDF2443033.1"
                     /translation="MNCKWISKIDERKKCHREADSSGYCIFHKENKSDEEIQLMMDTL
                     HKEEISEFNGFVFENEFNAEEILTYNYKILDFSESIFKQKANFKKYIFKKNIIFNYTE
                     FRDKVLFNGCVFLENCDFNRTIFSKHYINDRIFEKVKFKGPDLVVNKVENFPRMDGII
                     FSMCTKFVLKNVEYGKSEYEHGKINYRIARNQATKIGEYEMIGFYYYKERIYSSKIMK
                     RSNYPTFSDYLVEKFFDQIARYTTGYGEKPWNILLVIIAIISVFALLYLFVGIESSNS
                     TLVALDINNIGDYSLSEIFKMYMDLWYFSMATFSTVGYGDMVATSLIGKALAGIEVFF
                     GVTIGAIWASVIIKRMIR"
     gene            1191..2375
                     /locus_tag="PC512_003314"
     CDS             1191..2375
                     /locus_tag="PC512_003314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HDF2443034.1"
                     /translation="MKNALKKIISLAMILVFIIPNYSYADDKSVDKYSKTSILIDQET
                     GRVLYSKEPDMKVPLASLSKMMTFLLAIEAIENKEVKETDKVKIDKSIASVKGSSYKL
                     KDGEEVPLIELMRGLMIVSGNDAAIAIAKHVCKTKEAFVDRMNKKAKEIGMSNTHFLN
                     PNGLPIYDLSNPKKPAKENISTAKDIAILGKYMFDHYEKQVTAITDMETYTNSDRSFE
                     KSNTNALLRIIPEVDGIKTGYTGNAGYCLSFSMVVNKNDKNEKKRRVIGVVLGTNHKN
                     KRTSASLALLKYGKENFNMKKVIDKDSFIGKKYIKGTKELEVTLKAKDELYTILKDDE
                     SIKSEVKIKNIEYPVKKGDTMGIIKYYTNSGDLLGSVDIVSNNSIDNVSLKTKLKMKF
                     AN"
     gene            2582..3295
                     /gene="rpsB"
                     /locus_tag="PC512_003315"
     CDS             2582..3295
                     /gene="rpsB"
                     /locus_tag="PC512_003315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HDF2443035.1"
                     /translation="MSVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIYIIDLQ
                     KTVKKVEEAYKFTKEVAETGKPILFVGTKKQAQDAIKDEAERCGMYFVNERWLGGMLT
                     NHKTIKTRINKLRELEKMEEEGVFNVLPKKEVIKLRAEKEKLEKYLGGIKDMPELPGA
                     MFVVDPRKENIAIQEAHRLGIPVVGIVDTNCDPEQLDFAIPGNDDAIRAVKLITGAMA
                     TAVIEGRQGAEEEVAEDQE"
     gene            3374..4285
                     /locus_tag="PC512_003316"
     CDS             3374..4285
                     /locus_tag="PC512_003316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HDF2443036.1"
                     /translation="MANITAQMVKELRESTGAGMMDCKKALQEAEGNMEKAVDLLREK
                     GLSKAAKKAGRVAAEGLVAIEMNDDNTVASMVEVNSETDFVAKNEDFKVFVKDAACMA
                     LATDKEDIASLLGETHKEGITLQEVLNNRVAKIGEKLDFRRFAKVVTNGQVAGYIHGG
                     GKIGVLVEMETEARDAKVLELGKDVAMQVAAMNPKYVSRDEVDAEYIAHETEVLTQQA
                     LNEGKPANIVEKMVKGRLEKELKEVCLLEQTFVKNPDITVKQLVADVAKAVGSDIKVV
                     KVVRFEVGEGIQKREENFAEEVAKQLK"
     gene            4370..5074
                     /locus_tag="PC512_003317"
     CDS             4370..5074
                     /locus_tag="PC512_003317"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HDF2443037.1"
                     /translation="MDKPMYKRVLLKLSGEALAGERGFGINNDVVNDIAIAIKKIQEI
                     GVEVAVVVGGGNFWRGRTSEGMDRTTADYIGMLATVMNAMALQDALENIDVATRVQTA
                     IDMRQIAEPYIRRRAVRHLEKERVVIFGAGTGNPYFTTDTTAALRAAEMEAEVILLAK
                     NVDAVYDKDPKVHADAKKFTELSYMEVIQKELKVMDSTATSLCMDNKIPIKVFELTTE
                     NIIRAVKGENIGTTVK"
     gene            5100..5657
                     /gene="frr"
                     /locus_tag="PC512_003318"
     CDS             5100..5657
                     /gene="frr"
                     /locus_tag="PC512_003318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HDF2443038.1"
                     /translation="MKLEIHKQLEEKMNGTIDALKFEFGTIRAGRANAQMLDKIRVDY
                     YGTPTPINQIGAISVPEPRILMISPWDKSAMHEIEKAIANSDLGLNPSNDGEVIRLSV
                     PALTEERRKELAKKASKAAEEFKVRIRNERRDANEKIKKMEKGGELTEDELKKAQDEV
                     QKMTDKFIKEIDTLLSKKEKDIMEV"
     gene            5660..5863
                     /locus_tag="PC512_003319"
     CDS             5660..5863
                     /locus_tag="PC512_003319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443039.1"
                     /translation="MKKYYNLLGLHVDEVKQYFDEQNINYTVKSIEGKKDKEKLVVPR
                     VIKISEIGDSVELIITYFSDSLV"
     gene            5892..6626
                     /locus_tag="PC512_003320"
     CDS             5892..6626
                     /locus_tag="PC512_003320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HDF2443040.1"
                     /translation="MNNNIIYDIDLNNIPTHIAIIMDGNGRWAKARFLPRTAGHKAGV
                     ETIRDIVKECSKLGVKHLTLYAFSTENWKRPKLEVDTLMNLLSTYLRNEIAELHQNNV
                     KVTAIGDISALPKTCIRELNSAKELTKNNTGVNLNLALNYGSRADIKNALIDIVKNCE
                     SGKIDINNIDEDIIKNYLSTKSIPDPDLVIRTSGEQRLSNFLLWEVAYSEFYFTDIHW
                     PDFKKEELQKAIYVYQRRDRRFGGLK"
     gene            6639..7418
                     /locus_tag="PC512_003321"
     CDS             6639..7418
                     /locus_tag="PC512_003321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HDF2443041.1"
                     /translation="MLTRIIASLALVPLFLFVVYGGIPLYIAETAIVYIALHEFYKAF
                     KIKDVHPIFIIGYLFSIYLAVKNIFNLPLEYTYAVIFILFLASIIYMLMGKNNVIDVS
                     ITFLGVFYIGVFLDFIIITINGFEKGSIYVWLIFVISFMTDIFAYFSGYLLGKHKLIP
                     KVSPKKTIEGAIGGIIGSTLCCILFGYLFGIDLLQLAIIGSIGSVIAQLGDLFASSIK
                     RYVGIKDYGKIIPGHGGILDRFDSVILVAPFVYSAIKFFIR"
     gene            8242..10053
                     /locus_tag="PC512_003322"
     CDS             8242..10053
                     /locus_tag="PC512_003322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HDF2443042.1"
                     /translation="MKKKYDFLIYSAIWLVIIILFIFSLYHSIEHIKIISHTGTIRSE
                     TQKVVKQELNNERNDDLIKRLDNILIKLRTGNGENGFQRCDNKEFQQKLNQMDSMWES
                     MKKEIIKVRNGASGDKLYKLSEEYSVLSNQIVFISEKHSNAKLYSFATALFIYLIFST
                     ISLLIWEYYNKKRFKRIFYTDNLTKIKNQVAFENRAIEILHNASNKEYVLLNIDIDNF
                     KYINDTHGYEYGDKVLIIVAAALSKTFNIKETCARIGSDNFVILAKYRDSLLEDIREM
                     LTNAIISELDMNVTQTISYCIGAYLVEIDNLGYKSINSIMDKANIAHKVSKTRGISST
                     VWYNENLLKQLQMENSIYNYMYKAIENEEFHMYLQPKFQISSLNVVSAEALVRWFSPE
                     LGFLSPDEFIPLFEKSGFIIELDFYMLKKACSFVRKTFMKKNQYTYPIAVNFSRVTIY
                     QNSFYQRFLDTVKEYEIPFKYIEIEVTESAFNEISQPVISILEELKKLGFLISMDDFG
                     SGYSSLSLLCSLSINGLKLDKSLLKETFNREKVYSIIQCIIEMSHRIGMSVVCEGIET
                     KKDLEFLNTVKCDVGQGFYFSKPIEEKEFFNKYVTKK"
     gene            complement(10141..10722)
                     /locus_tag="PC512_003323"
     CDS             complement(10141..10722)
                     /locus_tag="PC512_003323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443043.1"
                     /translation="MLYLLKINQFEKSYDIGIFKNEQSIYKFIAKIPFVKKDNSNFNY
                     TNYYMEFEDIPEYYEVNFNNYLYIITRFSFIPDGTEIFFTWEEIHCWDEKVATEKTFI
                     NGETLVDSYNFPNNEVKDYIQKRESLYIETKKYYEEKGLKIERHALGSEDGEYVELTN
                     DSILYLLDIEAVEIREQSKNIEEFLYKYKKRFK"
BASE COUNT         4326 a         1097 c         1875 g         3439 t
ORIGIN      
        1 attgttttgt actggaggat atatatttat gaattgtaaa tggatatcta aaatagatga
       61 gagaaaaaaa tgtcatagag aagcagattc ttctggatat tgtatctttc ataaagaaaa
      121 taagtctgat gaagagatac aattgatgat ggatactctt cataaagaag agataagtga
      181 atttaatgga tttgtttttg aaaatgaatt taatgcggaa gaaatattaa cttacaatta
      241 taaaatactg gatttttctg aatccatatt taaacaaaaa gcaaatttta aaaaatatat
      301 ttttaaaaag aatattattt ttaactatac agaatttaga gataaagttt tatttaatgg
      361 ttgtgtattc ttagaaaact gtgattttaa tagaaccata tttagtaaac actatataaa
      421 tgaccgtata tttgaaaaag tgaaatttaa aggacctgat ttggtagtta ataaagtaga
      481 aaattttcca cgaatggatg gaataatttt tagcatgtgt acaaaatttg tgttaaagaa
      541 tgttgaatat ggaaaaagtg agtatgagca tggcaagata aattatagaa tagctagaaa
      601 tcaagcaaca aaaattggag aatatgagat gataggattt tactattata aggaaagaat
      661 ttatagtagt aaaataatga aacgttctaa ttatcctacc ttcagtgatt atttagttga
      721 aaaatttttt gaccaaatag cacgttacac aacaggttat ggagaaaagc catggaatat
      781 attattagtt attatagcaa taataagtgt ttttgcttta ttatacttat ttgtaggcat
      841 agaaagttca aatagcacac ttgtagcttt agatataaat aatataggtg attactcact
      901 aagtgagatt ttcaaaatgt atatggattt atggtatttt agcatggcta catttagtac
      961 agtaggatat ggagatatgg ttgctacaag tttgattggg aaagcattgg caggtataga
     1021 agtatttttt ggagttacaa taggagcaat ttgggcatct gtgattatta aaagaatgat
     1081 aaggtaatat ttgtgtaaat atggataggt attaattact agatataaat tggactaaat
     1141 agggaaaatt taaatataaa tatacttaat aatccaagaa ggtgaaaaat ttgaaaaatg
     1201 cactaaaaaa aattatatca ttagccatga ttctagtttt tataatacca aattattcat
     1261 atgcagatga taaatctgta gacaagtatt caaaaacatc tatacttata gaccaagaaa
     1321 caggtagagt tttatatagt aaagaacctg atatgaaggt accattagct agtttaagta
     1381 agatgatgac ttttttactt gcaatagaag ctattgaaaa taaagaagta aaagaaactg
     1441 ataaggtaaa aatagacaaa tctattgcat cagtaaaagg gtcaagttat aaacttaaag
     1501 atggtgaaga agtgccactt atagagctta tgagaggtct tatgattgta tcaggaaatg
     1561 atgcggcaat tgctatagca aaacatgttt gtaaaacgaa agaagcattt gtagatagaa
     1621 tgaataaaaa agcaaaagaa ataggaatga gtaatacaca ttttctaaat ccaaatggtc
     1681 ttccaatata cgatttaagc aaccccaaaa aaccagcaaa agaaaatatc tctactgcaa
     1741 aagatatagc tattcttgga aaatacatgt ttgaccatta tgaaaaacaa gtaacagcta
     1801 taactgatat ggagacatat acaaattcag atagaagttt tgaaaaaagc aatacaaatg
     1861 cattattaag aattatacca gaagtagatg gtataaaaac tggatatact ggcaatgctg
     1921 gatattgctt atcattttct atggttgtaa ataaaaatga taaaaatgag aaaaaacgta
     1981 gagtaatagg ggttgtatta ggtactaacc ataaaaataa aagaacctct gcttcattag
     2041 ctctactgaa atatggaaaa gaaaatttca atatgaaaaa agtaattgat aaagatagct
     2101 ttattggtaa gaaatatata aaaggaacga aagagttaga ggttacatta aaagcaaaag
     2161 atgaacttta tacaatatta aaagatgatg aaagtataaa gtcagaagtt aagattaaaa
     2221 atatagagta ccctgttaaa aaaggtgata ctatgggtat tataaaatat tatactaatt
     2281 caggtgactt acttggaagt gtagatatag taagtaataa tagtatagat aacgtatcat
     2341 taaaaacaaa attaaaaatg aaatttgcaa attaaattca aaaaatggta taaaatacac
     2401 aaaaaaatat aaaaatagaa aatatggaaa aaatattgtt atttcttcac ctctgtgata
     2461 tactactaga ggtgaaaaaa taaaataaat cacacacagc attgggatcc ttaaaaggtg
     2521 cctattacat ggttttttag ggagaagatc aagctggagg tataaaacca ggaggtaaga
     2581 tatgtcagta atatcaatga aacaattatt agaagcaggt gttcactttg gtcaccaaac
     2641 aagaagatgg aaccctaaaa tggctaagta tatattcaca gagagaaatg gaatatatat
     2701 aatcgactta caaaaaacag ttaaaaaagt tgaagaagct tacaagttca ctaaagaagt
     2761 agctgaaaca ggaaagccaa tcttattcgt aggaactaaa aaacaagctc aagatgcgat
     2821 aaaagatgaa gctgaaagat gtggaatgta ctttgttaat gaaagatggt taggtggaat
     2881 gttaacaaac cacaaaacta taaaaacaag aataaataaa ttaagagaat tagaaaaaat
     2941 ggaagaagaa ggcgtattta atgttcttcc taaaaaagaa gttataaaat taagagctga
     3001 aaaagaaaaa ctagaaaaat acttaggtgg aataaaagac atgcctgaat taccaggtgc
     3061 aatgttcgta gttgacccaa gaaaagaaaa catagctatt caagaagctc atagattagg
     3121 tataccagta gttggtatag ttgatactaa ctgtgaccca gaacaattag actttgctat
     3181 accaggaaat gatgacgcta taagagccgt aaaattaata actggtgcta tggcaacagc
     3241 tgtaattgaa ggtagacaag gtgctgagga agaagtagct gaagaccaag aataataatt
     3301 tgacaattaa atggtaaggg tcgcccttac catttataat atggaataga ataagtagga
     3361 ggaaacttaa aaaatggcta atataactgc tcaaatggta aaagagttaa gagaaagtac
     3421 aggcgcagga atgatggact gcaagaaagc tttacaagaa gctgaaggaa acatggaaaa
     3481 agcagtagat ttattaagag aaaaaggatt atcaaaagct gctaaaaaag ctggtagagt
     3541 tgctgctgaa ggtctagttg caatagaaat gaatgatgat aatacagttg cttctatggt
     3601 agaagttaac tcagagacag atttcgttgc taaaaacgaa gacttcaaag tgttcgttaa
     3661 agatgctgct tgtatggcat tagctactga taaagaagat atagcttctt tattaggtga
     3721 aactcataaa gaaggaataa ctttacaaga agttttaaat aatagagttg caaaaatagg
     3781 tgagaaatta gactttagaa gatttgctaa agttgtaact aatggacaag ttgctggata
     3841 cattcacggt ggtggaaaaa taggtgttct tgttgaaatg gaaacagaag ctagagatgc
     3901 taaagtttta gaattaggta aagatgtagc tatgcaagtt gctgctatga atcctaagta
     3961 tgtttcaaga gatgaagtag atgctgaata catagcacat gaaacagaag tattaactca
     4021 acaagcttta aatgaaggaa aaccagctaa tatagttgaa aaaatggtta aaggaagatt
     4081 agaaaaagaa ttaaaagagg tttgtttatt agagcaaact ttcgttaaaa atccagatat
     4141 aactgttaaa caattagttg ctgatgttgc taaggcagta ggttctgata taaaagttgt
     4201 taaagttgtg agattcgaag ttggtgaagg tatacaaaag agagaagaaa actttgcaga
     4261 agaagttgct aagcaactta agtaataacc aaagagagaa cacgcaggtg ttctcttttt
     4321 taaaaaatag aaaaaattgg atatgaagga ttgaaatagg aggtttctga tggataaacc
     4381 aatgtacaaa agggtattgt taaaattaag tggagaagca ttagcaggag aaagaggttt
     4441 tggtataaat aatgatgtag ttaatgatat tgctattgct ataaaaaaaa tacaagaaat
     4501 aggtgttgaa gtagctgtag tagtaggtgg aggaaacttc tggagaggca gaaccagtga
     4561 aggaatggac agaactactg ctgactatat aggaatgtta gctacagtta tgaatgcaat
     4621 ggcgctacag gatgcactag aaaatataga tgttgctaca agagttcaaa ctgctataga
     4681 catgagacaa attgcagaac catatataag aagaagagca gttagacact tagaaaagga
     4741 aagagttgtt atatttggtg caggaacagg aaacccttac tttacaacag atacaactgc
     4801 tgctttacgt gctgctgaga tggaagcaga agttatattg ttagctaaaa atgttgatgc
     4861 agtatatgac aaggatccaa aagtacatgc agatgctaag aaatttacag aattaagtta
     4921 catggaagtt atacagaaag aattaaaagt aatggattct acagctacat ctttatgtat
     4981 ggataataaa attccaataa aggtatttga gcttacaaca gagaatataa taagagcagt
     5041 aaaaggcgaa aatataggaa ctactgtaaa ataatgaaga atgaaggagg agtaaaatta
     5101 tgaaactgga aatacataag caattagaag agaaaatgaa tgggacaatt gatgctttaa
     5161 agtttgaatt tggaactata agagcaggaa gagctaatgc acaaatgcta gacaaaataa
     5221 gagttgatta ttatggaact ccaactccaa taaatcaaat aggtgctata tctgtaccag
     5281 aaccaagaat attaatgata tctccttggg ataaatctgc tatgcatgaa atagaaaaag
     5341 cgatagctaa ctcagactta ggattaaatc catcaaatga tggtgaggtt ataagacttt
     5401 ctgtacctgc tttaacagaa gaaagaagaa aagaattagc taaaaaagct agtaaagctg
     5461 cagaagaatt taaagttaga ataagaaatg aaagaagaga cgccaatgag aaaattaaaa
     5521 agatggaaaa aggcggagaa ttaactgaag atgaattaaa aaaagcacaa gatgaagttc
     5581 aaaaaatgac tgataaattt ataaaagaaa tagatacatt attatctaaa aaagaaaagg
     5641 acataatgga ggtataatat tgaaaaaata ttataacctt ttaggtcttc atgtagatga
     5701 ggtaaaacaa tattttgatg agcaaaatat aaattatacc gtaaaatcta ttgaaggtaa
     5761 aaaggataaa gaaaaacttg tagttcctag agttataaaa atatctgaga taggtgatag
     5821 tgtagaactg ataatcacat acttttctga ctccttagtt taaggagtca gaacaatatt
     5881 ggaggcaaaa tatgaataac aacattatat atgatataga cttaaataac atacctactc
     5941 atattgctat tataatggat ggaaatggaa gatgggcaaa agctagattt cttccaagaa
     6001 ctgcaggaca taaggctgga gtagaaacta taagagatat agtaaaagaa tgctcaaaat
     6061 taggtgttaa gcacttaaca ttatatgcat tttcaacaga aaactggaaa agaccgaaac
     6121 ttgaagttga cacacttatg aacttattat ctacatactt aagaaatgaa atagctgaac
     6181 ttcaccaaaa caatgtaaaa gtaactgcta taggagatat aagtgcttta ccaaaaactt
     6241 gtataagaga attaaactca gctaaggaac tgacaaaaaa caatacagga gttaacttaa
     6301 atttagcatt aaactacgga agtagagcag atataaaaaa tgctcttata gatatagtaa
     6361 aaaattgtga aagtggtaaa atagatataa acaatattga tgaagatatt ataaaaaact
     6421 atttaagcac aaagtctata ccagatccag acttggtaat aagaacaagt ggtgaacaaa
     6481 gattgagtaa ctttttactt tgggaagttg cttattctga gttttacttt actgatatac
     6541 attggcctga ttttaaaaaa gaagaactac agaaggctat atacgtatat caaagaaggg
     6601 atagaagatt tggaggactt aagtaaggag attattttat gcttacaaga attattgctt
     6661 cactagctct ggttccatta tttctatttg ttgtatatgg aggtattcct ctatatatag
     6721 ctgagacagc aatagtttat attgcattgc atgagtttta taaggcattt aaaataaaag
     6781 atgtacatcc aatattcatt ataggatatt tattttctat ttatttagct gtaaaaaata
     6841 tttttaattt accattagaa tatacttatg cagtaatttt tattttattt ttagcaagta
     6901 taatttatat gttgatgggc aaaaacaatg ttatagatgt ttcgattacg tttttaggag
     6961 ttttttatat aggagtattt ttagatttta taattataac tataaatgga tttgaaaaag
     7021 gtagtatata tgtatggctt atatttgtga tatcttttat gacagatata tttgcatatt
     7081 ttagtggtta tttacttgga aaacataagc taattcctaa agttagtcct aaaaagacta
     7141 tagaaggagc tattggagga ataataggaa gtacactttg ttgtatttta tttggatatt
     7201 tatttggcat tgatttgctt caattagcga taataggaag tataggaagt gtaatagctc
     7261 aattaggaga tttatttgca tcttctataa agagatatgt agggataaag gattatggaa
     7321 agataatacc tggtcatggg ggtatattag atagatttga tagtgttata ttagttgcac
     7381 cttttgtata tagtgcgatt aaatttttta ttagataaag attggttgga tttaaaagag
     7441 caatctataa ttgctagtaa tgaaaatagc tatgtaactt ttaaatgcag agatattctg
     7501 cagttattag ttacatggct attttcattg ttcaaaaatt tagaagacct tggggaattg
     7561 tataagaata ggtattactt tataatagta tactatattt gtagtgagta tattttttat
     7621 actataacta tcattaaaaa atattttttt gtttaataat ttcgatattt ttagctatat
     7681 tatatattta taatatatat gtataaatgt aactaattta ttatccattt ataaatttta
     7741 tttttaaata taattaataa gaaataagta aattattggt cttattacac aaaaatagat
     7801 ataatttaag taatatacca aaaaaaagga atatatttac ataatatgat aaaataaatt
     7861 caaagagtta aattgtaggt aaatagtatt ttaattattt attaaaatat agattatgta
     7921 tatgccaaat ttaaaaagag acataaagac attatacaaa tatattattg gggtgatatt
     7981 ttataagaaa agaagtgatg cagtaaatta attgagcaat ttaaaaatga tttaatgata
     8041 gtgttgatga atgtttaaaa agaaatttta gaaaaacgta tattgctgtt tgtgttggag
     8101 gtgatgaatt tgtataattt ataggatata aatgattaaa ctatttaaga taaatacata
     8161 tcactgtaaa atattgataa tcatttttta taagagattg attatttgca aattatatat
     8221 attacaaatg aggtaacaat aatgaagaaa aaatatgatt ttttaattta ttctgctatt
     8281 tggctagtta ttattattct ttttatattt tctctatatc acagtataga gcatattaaa
     8341 attataagtc acactggtac tattcgcagt gaaactcaaa aggttgttaa gcaagaattg
     8401 aataatgaaa gaaatgatga cttgataaaa cgactggata atattctgat aaagctaaga
     8461 acaggtaatg gagaaaatgg atttcaaaga tgtgataata aagaatttca acaaaaacta
     8521 aatcaaatgg attctatgtg ggaatctatg aagaaagaaa ttataaaagt tagaaatggt
     8581 gcttcaggtg ataaattata taaattgagt gaagagtatt ctgtgttgtc taatcaaatt
     8641 gtttttatat ctgaaaaaca ctctaatgca aaattgtatt cttttgctac tgcactattt
     8701 atttatctta tattctcaac aataagtctt ttaatttggg aatattataa taaaaaaagg
     8761 tttaaaagaa tattttatac tgataattta acaaaaataa aaaatcaggt tgcatttgaa
     8821 aacagagcga ttgaaatttt gcacaatgca tctaacaaag agtatgtact gctaaatatt
     8881 gatattgaca attttaaata tattaatgat acacatggat atgaatatgg agataaagtt
     8941 ctaataatag ttgcagctgc actttctaaa acttttaata tcaaagaaac ttgtgcaaga
     9001 attggttcag ataattttgt aatacttgca aaatatagag attctctttt agaggatatt
     9061 cgggaaatgc taactaatgc tataatctct gaattagata tgaatgtaac tcaaactata
     9121 tcttattgta taggagcgta cttagttgaa attgataatt taggttataa atccatcaat
     9181 tctataatgg ataaggcaaa tattgcacac aaggtaagta aaacaagagg aatttcctcc
     9241 acagtatggt ataatgaaaa tctgttaaaa cagttacaaa tggaaaatag tatttataat
     9301 tatatgtata aagcgataga aaatgaagaa tttcatatgt atttgcaacc taaatttcaa
     9361 atatcttctt taaatgttgt aagcgcagaa gctcttgtaa gatggttttc tccagaactt
     9421 ggttttttat caccagatga atttattcca ttgtttgaaa aaagtggatt tattattgaa
     9481 ttggactttt atatgttaaa aaaagcgtgt tcatttgtaa gaaaaacgtt tatgaaaaaa
     9541 aatcaatata catatccgat tgcagttaat ttttcaaggg ttactattta ccaaaatagt
     9601 ttttatcaaa ggtttttaga tactgttaaa gaatatgaaa ttccttttaa gtatatagag
     9661 atagaggtaa ctgaaagtgc ttttaatgaa atatctcaac cagttatttc aattttagag
     9721 gaacttaaaa agttaggatt tttaatttca atggatgatt ttggttcagg atactcttca
     9781 ttaagtcttt tatgttctct atctattaat ggattgaagt tagataaaag cttacttaaa
     9841 gaaaccttta accgggagaa agtatatagt attattcaat gtattattga aatgtcacat
     9901 cgtataggca tgtctgttgt atgtgaaggt attgaaacta aaaaagactt ggaattttta
     9961 aatacagtta aatgtgatgt aggacaaggg ttttattttt ctaaaccgat agaagaaaaa
    10021 gaatttttta acaaatatgt aactaaaaaa taatataatt atttttatca gtctatacat
    10081 tgagtcattt tatatctcgt taaatgactc aatgtactgt tatgtatttt aaaatataaa
    10141 ttatttaaaa cgttttttat acttatatag aaattcttct atattttttg attgttctct
    10201 tatttcaact gcttctatat ctagtaaata aagtatagaa tcatttgtaa gttcaacata
    10261 ttcaccatct tctgaaccga gtgcatgtct ctcaattttt aatccttttt cttcataata
    10321 tttttttgtt tctatatata atgattctcg cttttgtatg tagtctttca cttcattatt
    10381 tggaaagtta tatgaatcca ctaatgtttc gccatttata aaagttttct cggtagcaac
    10441 tttttcatcc caacaatgga tttcttccca agtaaaaaat atctcagttc catctggaat
    10501 gaatgaaaac ctggtaataa tatataaata attattgaaa tttacttcat aatattcagg
    10561 aatatcttca aattccatat agtaatttgt ataattaaaa ttactattat ctttttttac
    10621 aaagggtatt tttgcaataa atttatatat tgattgttca tttttaaaaa ttcctatatc
    10681 ataacttttt tcaaattgat taatttttaa taaatacaac attctttctc cttttat
//
LOCUS       DAMJVG010000109        10507 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.114, whole genome shotgun sequence.
ACCESSION   DAMJVG010000109 DAMJVG010000000
VERSION     DAMJVG010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10507)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10507)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10507
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.114"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            134..751
                     /locus_tag="PC512_003324"
     CDS             134..751
                     /locus_tag="PC512_003324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 domain-containing protein"
                     /protein_id="HDF2443044.1"
                     /translation="MEIFAIGHSNYPYDKLINMIKKYDINCVVDIRETPYSKYNIQYN
                     KEAFNESLRNSGFLYIYMGKEFGAKRTNKDVYTQEGYADFEKVAKEDIFLNGIERLKK
                     GCQMGYRIVLLGAMQEPIRCHRSILVGKVLNKEGFDVKYIMHEGNLAYQEDIEESLLD
                     KYFSDRKQLSIDNLLGSALTREEMIQEGYKLANKEIGYRTEKLGK"
     gene            complement(908..1360)
                     /locus_tag="PC512_003325"
     CDS             complement(908..1360)
                     /locus_tag="PC512_003325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443045.1"
                     /translation="MVNLNANNLNVNMVYPISSTAPIRFRRYTVSYLENMENIYLTIA
                     TYFDTLGLGTMNIDKVYGQWAWFTDNIYDLNLFVFVGNYPYQIAKNRYDTFVDILPVA
                     ITSIVNGDRIFLISNPCLLNSKITVRFISSHPTLNRTVDYGNIRDFIF"
     gene            1808..3166
                     /locus_tag="PC512_003326"
     CDS             1808..3166
                     /locus_tag="PC512_003326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2443046.1"
                     /translation="MFIRKNVIKLAIPIMIEQTFVMLLGVFNTMMAGHIGEEAVSAVG
                     MVDSINNIFISVFAALSVGATVVVAQQIGKKDGEKVNETIKQALVSGVILSFTITILM
                     WVFRTGVINLFYGSAEELVKSNAKLYIEFTLFTYPFIATQQIANGLLRGCGDVKKPMY
                     VTMFMNIVNVTLGYILIYGIDLNPLGINLQTPSYGITGAAISIAIARIIGCIVIIRAL
                     FKGNEFISMGKIFPFKIDVETQKSIFNIGIPAGVEQLLFNAGKLIVQVFIVTMGTSAI
                     ASNAIGMSIASIINVIGNALALSATTLVGQYIGRGDIKGAKSTLLYLTKFATICLFIV
                     GAIFIPIAPWISSMYTQNASVIDISTQLIRSDCLAMVIWPISFVLSAGLKGASDTRYT
                     MMTAVIGMWIFRIFTGYVLGVVLEFGVLGIWIGMYTDWLVRGTLYCLRLRGTKWLKHK
                     VA"
     gene            3439..3819
                     /locus_tag="PC512_003327"
     CDS             3439..3819
                     /locus_tag="PC512_003327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDF2443047.1"
                     /translation="MINKIGKITLYVNNQEDAKLFWTEKLNFVVTYEKEMGPNMKWVE
                     VAPSKNEFTTFVLYDKNLMMRQNKEINVSHPSIILSTRDINGTYEQMANNEVEVGELM
                     EMPYGRMFSFKDQDGNDYLVREDK"
     gene            3944..4144
                     /locus_tag="PC512_003328"
     CDS             3944..4144
                     /locus_tag="PC512_003328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443048.1"
                     /translation="MFKKMAVLKDIATKIGRKKAYELLEMVEGNDAFVAEVKIKKNGI
                     ESKKEEIMLKDNQKIILEYIEG"
     gene            4340..5068
                     /locus_tag="PC512_003329"
     CDS             4340..5068
                     /locus_tag="PC512_003329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2443049.1"
                     /translation="MLEIKNLSFNVESNNEELGIINDVSLSFERGKLIVITGPNGGGK
                     STIAKLIMGIEKATSGQIILDGEDITNLSITERAKKGIGYAFQQPPRIKGMTVENLLT
                     LAHGKPLSTDVCCQYLTDVGLCSKDYLNREVDNSLSGGEMKRIEIATLFARDLKVSIF
                     DEPEAGIDLWSFGKLNESFKKIHEESNQTIIIISHQERILELADEIIVLQDGSVKSHG
                     TKEAILPEIMCQVNSSCELMKDMN"
     gene            5090..6007
                     /locus_tag="PC512_003330"
     CDS             5090..6007
                     /locus_tag="PC512_003330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SufD family Fe-S cluster assembly protein"
                     /protein_id="HDF2443050.1"
                     /translation="MNKIDLNLLEKVAELRGTPLGAYNIRKNGQGVERHSTENVTIIP
                     KTDKPGIDIIVKPNTKGENVHIPVIVTETGVQDMVYNDFEIGENADVVIIAGCGIHNC
                     GCDDSEHNGIHRFFLRKGARLKYVEKHYGEGDGEGKRILNPVTIVNMDEDSYCEMETI
                     QIKGVDSTKREMDANLGKGAKIVVFEKLLTHGNQVAESNMKVILEGENSSAQVVSRTV
                     GQDNSKQKFNPCVIGDSLCSAHVQCDSIIMGNSQISAIPEIAANHPDALLVHEAAIGK
                     IAGDQILKMMTLGLTEEEAEQQILNCFLK"
     gene            6149..7333
                     /locus_tag="PC512_003331"
     CDS             6149..7333
                     /locus_tag="PC512_003331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HDF2443051.1"
                     /translation="MKNLLIRNGTIISPTDGIKFEKRDILVLHGKIYAIGLNLKEKIR
                     KEKLLTNKEFEIINADNMYISPGFIDVHTHCYKRKLPTGMDSDSIGIEKGSTVIFDAG
                     TAGPLNYYDFKKKYMDECKTEVYSFLNVTNEGLNILNESTSLDVINFDKVESVVEKNI
                     EKIKGIKVKASKFQSNESGIDIIKKSKQVAKKLNLPLVVYIGEYPSYIDEVMNILGKG
                     DVVTPVYGNSTNGILKESGTLRKSVINAKNRGVLFDVCHGLNQFDFKVFKKAIKQGLE
                     PDLISTDMHIKNMKDVNYSLLSVINKIMELGISLEKCIEKVTEYPTKIFDLHGNKGRI
                     KIGGEGDFTIFTMEECNDIIKDYNNNELVLNKKLRLQYTVKSWMKSSEVYRHGYENTI
                     IN"
     gene            7440..7628
                     /locus_tag="PC512_003332"
     CDS             7440..7628
                     /locus_tag="PC512_003332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HDF2443052.1"
                     /translation="MKAFVDKDVCVACGACIGTCPDVFSMSDEGHSVAIEGEIPADLQ
                     DLCKEAEEGCPVSAITVK"
     gene            7778..8428
                     /locus_tag="PC512_003333"
     CDS             7778..8428
                     /locus_tag="PC512_003333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HDF2443053.1"
                     /translation="MKKNYEIVLFDLDGTLTDPKEGITKSIQYSLNSFGIKEDLENLD
                     QFIGPPLHDTFKEYYKFEDKKTKEAVEKYREYFADKGIFENKIYENIKEILEMLYKNG
                     KILLVATSKPTVFAETILRYFDIDRYFKYIAGSNLDGTRVNKNEVIQYVLDLCNVKDK
                     DKVIMVGDRKYDIIGAKKIGIDSIGVLYGYGSFEELSESEPTYIVENVESIKDILL"
     gene            8531..9469
                     /locus_tag="PC512_003334"
     CDS             8531..9469
                     /locus_tag="PC512_003334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDF2443054.1"
                     /translation="MKSILIMGGSDFIGSALAKRLIKCGYQIDILTNGKKEIDYNGFK
                     EHLICDRKVRKDMENIITGRKYDYIYDMTAYTKEDVSNLIDFISMDNLKKYIVLSAGA
                     VYKDSGRNIKEENEKGENENWGKYGLNKKEAEDFIINSPIPYIIIRPTYIYGENNNLY
                     REYYFFEKIEKNEKIPVPKGKQVSNQFIYIGDLVKVLESIMKNPHVREAYNVTNPQLI
                     SWDDLIYTCGEIIGKEPIIKYVDMEKVEFRERTYFPFRNIDFNLDINKLIEHGLYIPN
                     VLLKEGLTATYKWFSANKPKMHDRKMNKVESVMQIV"
     gene            9495..10346
                     /locus_tag="PC512_003335"
     CDS             9495..10346
                     /locus_tag="PC512_003335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDF2443055.1"
                     /translation="MNSKIKYFLKFFILIFILIFIYSVAIEPSLLIVKKYNISENGTL
                     IKSDTIESKSERIKVVQISDTQIGSFYSTKNLKKVANKINTLNPDIIVFTGDLIDYSN
                     KNPSVDEITTILSSMNARLGKFSVFGNHDYMYKLPRYYRQIMKNSNFNLLVNENKKIK
                     LKDDKYINILGVDEILNGNPNIKYLESQIDNKNFNLLLAHEPDLVDMLSKDTMNLVLS
                     GHSHGGQIRLPIKGALVTPPYGRKYTKGFYDINGNHLYVSSGLGSTKLPFRFFNIPEI
                     IEFNIII"
BASE COUNT         4274 a         1001 c         1854 g         3378 t
ORIGIN      
        1 atataaagta aaaaaatata caatatcaag aaaaaaagat attgggtatt taaagtaata
       61 ctttatttaa ttttaagtaa atcgggtatc tacatatata gatactaatt tcaaagaata
      121 ggagggtgtt tatatggaaa tattcgcaat aggacattca aattatccat atgataagct
      181 tattaatatg ataaaaaaat atgacataaa ttgtgtagtt gacattagag aaactccata
      241 ttctaaatat aatattcaat acaataaaga ggcatttaac gaatctctta gaaattccgg
      301 atttttatat atatacatgg gaaaagaatt tggagctaaa agaactaata aagatgtata
      361 tacgcaagaa ggttatgcag attttgagaa agtagcaaaa gaagatattt ttttaaacgg
      421 aatagaaaga ttaaaaaagg gttgtcaaat gggttatagg atagttttat taggagctat
      481 gcaagaacct ataagatgtc atagaagtat cttggtggga aaagtattaa ataaagaagg
      541 ttttgatgta aaatatataa tgcatgaagg aaatttggca tatcaggaag atatagagga
      601 atcattattg gataagtatt ttagtgatag aaagcaactg agtattgaca atttattagg
      661 gagtgcatta acgagagaag aaatgataca agaaggttat aagctagcta ataaagaaat
      721 aggatataga actgagaaac taggtaaata aaaatataca agtagataaa atacagtact
      781 tatcttaagt aaaataatat tatgaattta taatagctag gcatgatgtg ccaattaaaa
      841 atattctagt tatttaataa tatcattaaa tttagggtat tttttaatag cacatcatgt
      901 tgcagtttta aaaaataaaa tctctaatat tgccataatc aactgttcta ttaagagtag
      961 gatgactaga tataaatcta actgtaattt ttgaatttaa caaacaagga tttgaaatta
     1021 aaaatattct atctccattg acaatagaag taatagctac tggcaaaata tctacaaatg
     1081 tatcatatct gtttttagca atttgataag gataatttcc tacaaaaaca aatagattta
     1141 aatcatatat attatcagta aaccaagccc attgaccata aactttgtcg atattcattg
     1201 tgcctaaacc aagtgtatca aagtatgttg ctatagttaa ataaatattt tccatgtttt
     1261 ctaaatatga aacagtatat cttctgaaac gtatgggtgc tgtggaagaa ataggataaa
     1321 ccatatttac atttagatta tttgcattta aattaaccaa agtatcacat cctaaaatta
     1381 gtctataaaa tacaatattt aaatggatgc gattttgtta catctaaagt gtaatatttt
     1441 atatattgaa aaagtggtaa aagtttggat gattaaataa tattataaaa aatatataaa
     1501 atgtacttat tgttattgct acacgatagt gatacaatat taacgaaata tagctacttt
     1561 taataataac ggaaaatatt tatattaaat taataaatat tttaaatgtg gtatccataa
     1621 aaaataataa acataagata attataaaga tatactgtgt tcaaatgata ttaaacaaga
     1681 tttatattat ttgaaagcag tatattataa tgcgaacaat acaattctaa actttgcatt
     1741 gtcaatttac agttcgataa actaattaaa aattaaattt atataaagag ggaaaagagg
     1801 aatagggatg tttataagga aaaatgttat aaagttagca attcctataa tgatagagca
     1861 gacgtttgtc atgcttttag gagtatttaa tacaatgatg gcaggtcata ttggggaaga
     1921 agctgtatct gcagttggaa tggttgattc aataaacaat atatttatat ctgtatttgc
     1981 tgcactatct gttggagcta ctgttgttgt agctcaacaa ataggaaaaa aagatggtga
     2041 aaaggtgaat gaaactatta agcaggctct agtgtctgga gtaatattat cctttacaat
     2101 aacaatattg atgtgggttt ttagaactgg tgtaattaat ttattttatg gttccgcaga
     2161 agaattggta aaatcaaatg caaaattata catagagttt acattattta cgtatccatt
     2221 tattgcgaca caacaaatag caaatggtct tttaagaggg tgtggagatg taaagaaacc
     2281 tatgtatgtg actatgttta tgaatatagt aaatgtaaca ttaggatata tacttatata
     2341 tggtattgat ttaaatcctc taggaataaa tttgcaaaca ccatcctatg gcataacagg
     2401 tgcagctata tctattgcta tagctagaat aattggatgt atagtaatta taagagcttt
     2461 atttaaagga aacgaattta tatctatggg taaaatattt ccatttaaga ttgatgttga
     2521 aactcaaaag tctatattta atataggaat accagctgga gttgaacaac tactttttaa
     2581 tgcaggtaaa ttgattgttc aagtatttat agttactatg ggaacatcag caattgcatc
     2641 caatgcaata ggaatgtcaa ttgcatccat aataaatgta attgggaatg ctttagcttt
     2701 gtctgctaca accttggtgg gacagtatat aggacgtgga gatattaaag gagctaagag
     2761 tactttatta tatttaacta aatttgcaac aatttgttta tttatagtag gagctatatt
     2821 tataccaatt gcaccttgga tttcaagtat gtatactcaa aatgctagtg taattgacat
     2881 ctcaacacaa ttaattcgaa gtgattgttt agctatggta atatggccta tatcctttgt
     2941 attatcagca gggctaaagg gagccagtga tactagatat acaatgatga ctgcagtaat
     3001 aggtatgtgg atttttagaa tttttacagg ttacgtattg ggggttgtat tagaatttgg
     3061 agtgttagga atttggatag gtatgtatac tgattggctt gttagaggga ctttatattg
     3121 tttaagatta agaggaacaa agtggctaaa acacaaagtt gcatagaata tatgaaatca
     3181 cttttagatg gataactcta tttagaagtg attttttatg tagttattat cataattata
     3241 agtatgatat ataaggtgat taaattacat aaataaagcc tataatagta tggatactat
     3301 aaattatata ttgagcagaa ttacataatt tggcgataaa tattagaaat atatatctat
     3361 agaaaataat atatatgggt atattattaa atataaaaaa tattaggtat ttatttaata
     3421 ataaaggtgg gtattgttat gataaataaa ataggaaaaa taactctcta tgtaaataat
     3481 caagaggatg caaagttgtt ttggacagaa aaattgaact ttgtagtaac ttatgaaaag
     3541 gaaatgggtc caaatatgaa atgggtggaa gtagcaccaa gtaaaaatga atttacaaca
     3601 tttgtgttgt atgataaaaa tctaatgatg agacaaaaca aagagataaa tgtatctcat
     3661 ccatcaataa ttttaagtac aagagatatt aatggaactt atgaacaaat ggcaaataac
     3721 gaggttgagg ttggggaatt aatggagatg ccatatggaa ggatgttttc ttttaaagac
     3781 caagatggaa atgattattt ggtcagagag gataaataat tttacaaagt attaaattta
     3841 ctcaatatct gatataatta gagacaataa ttattataaa ctagtctagg attagaatta
     3901 tataattaaa aattaagtgt aaattttgag tagaggtgat aaaatgttta agaaaatggc
     3961 agtactaaaa gatatagcaa ctaaaatagg tcgtaaaaaa gcttatgaac tattagaaat
     4021 ggttgaaggt aatgatgcct ttgtagctga ggtgaagata aaaaagaatg gaatagaatc
     4081 taaaaaagaa gaaattatgt taaaagataa tcaaaaaata atattagagt atatagaagg
     4141 ctaattttta aatacatata agttgatata ctaaatttct gagatgagtt tacataaaac
     4201 tcatcttttt tacttttcaa taactttgtt ttattattta atatacattt tatctgctta
     4261 gagttgctga tatataaaaa ttactgatat aataaaagaa tggatattaa tgtaatattt
     4321 tatagaaaag aggggtatta tgcttgaaat aaaaaatctt tcctttaatg ttgagtctaa
     4381 caatgaggaa ctaggaataa taaatgatgt tagcctttca tttgagaggg gaaaacttat
     4441 tgttatcaca gggccaaatg gtggaggaaa atctacaatt gctaagctta ttatgggaat
     4501 tgaaaaagct acgagtggtc agataatttt agatggagaa gatataacaa atcttagtat
     4561 tacagaaaga gcaaaaaaag gaataggata tgcatttcaa caaccaccaa gaataaaagg
     4621 tatgacagtt gaaaatttac ttacacttgc tcatggaaaa ccattgtcta ctgatgtatg
     4681 ttgccaatat cttacagatg ttggattgtg ttcaaaagac tatttaaatc gtgaagttga
     4741 taactctctt tctggagggg aaatgaaaag aattgagata gcaactcttt ttgctagaga
     4801 tttaaaggtt tctatatttg atgaacctga agcagggata gacctttgga gctttgggaa
     4861 actcaatgaa agttttaaga aaatacatga agagtctaac cagactataa tcataatttc
     4921 tcaccaagaa agaatattag agttagctga tgaaataatt gttctacaag atggttcagt
     4981 aaaaagccat ggaacaaaag aggctatatt acctgaaatc atgtgtcaag ttaattcaag
     5041 ttgtgaatta atgaaagaca tgaattaatt agaaaggaag gcaaattaaa tgaacaaaat
     5101 agatttaaat cttttagaaa aagttgctga acttcgtgga actccattag gagcatacaa
     5161 tatacgtaaa aatgggcaag gagtagagag acattcaact gaaaatgtaa ctataattcc
     5221 taaaactgat aaacctggaa tagatattat agtaaagcca aatacaaaag gagaaaatgt
     5281 acatatacca gtaatagtaa cagagactgg tgtacaggat atggtatata atgattttga
     5341 aattggagaa aatgcagatg ttgttataat tgctgggtgt ggtatacata actgtggttg
     5401 tgatgatagt gaacataatg gtatacatag atttttctta cgtaaaggag ctcgcctaaa
     5461 atatgtagaa aaacattatg gtgaaggtga tggagaagga aagagaattt taaatccagt
     5521 tactattgtc aatatggatg aggattcata ttgtgaaatg gaaacaattc aaattaaggg
     5581 tgtagattca actaaaagag aaatggatgc aaacctaggt aaaggagcta aaatagttgt
     5641 atttgagaaa ttattaactc atggtaatca agttgcagaa tctaatatga aggttatctt
     5701 agagggggaa aactcttctg ctcaagtagt ttctcgtaca gttgggcaag ataattctaa
     5761 gcaaaagttt aatccttgtg ttattgggga ttccctttgt tctgcacatg ttcaatgtga
     5821 ttcaataatt atgggaaatt ctcaaattag tgctatacct gaaattgctg caaatcatcc
     5881 agatgctctt ttagtacatg aagcagctat tggaaagatt gcaggagatc aaatactaaa
     5941 gatgatgaca ttaggtctta ctgaagaaga agccgaacaa cagatactta attgcttctt
     6001 aaagtaaatt aaagatttta tttaatttaa tataattaat atagtataat atagtgaata
     6061 agtctaaaat atttttattt ttaggcttat tttctttatg taagaaaagc tattagagaa
     6121 attatattgt aattaggatg tggaataaat gaaaaatttg cttataagaa atgggacaat
     6181 aatatctcca acagatggta tcaaatttga aaaaagagat atcttggttt tacatgggaa
     6241 aatatatgct attggattga accttaaaga gaaaataaga aaagaaaaat tacttacaaa
     6301 taaagagttc gagataataa atgccgataa tatgtatatt tccccaggat ttatagatgt
     6361 tcacacccat tgttataaga gaaaattacc tacaggtatg gattctgatt caattggaat
     6421 tgaaaaaggt tctacagtta tatttgatgc aggtacagct ggtcctttaa actactatga
     6481 ttttaaaaaa aagtatatgg atgagtgtaa aacagaagta tattcttttt taaatgttac
     6541 aaatgaggga ctaaatatat tgaatgaatc aacttcttta gatgttataa attttgacaa
     6601 ggttgagtca gttgtagaaa aaaatataga aaagataaag ggtataaaag taaaagcgag
     6661 taaatttcaa tctaatgaaa gtggtataga tataattaag aaatcaaagc aagttgccaa
     6721 aaaattaaat ttacccttag tggtatatat aggagagtat ccatcatata tagatgaagt
     6781 aatgaatatt ttgggaaaag gagatgtggt tacaccagta tatggaaata gtacaaatgg
     6841 aatccttaaa gaatctggca cattaagaaa atcagtaata aatgcaaaga acagaggagt
     6901 attgtttgat gtatgtcatg gattgaacca atttgatttt aaagttttta aaaaagcaat
     6961 aaagcaaggt ttagagccag acctaataag tactgatatg catataaaaa acatgaaaga
     7021 cgtaaactat tctcttttaa gtgttataaa taaaattatg gaacttggga tatccttaga
     7081 aaagtgtata gaaaaagtaa ctgaataccc aacaaagatt ttcgatttac atggaaataa
     7141 aggcagaata aagattggtg gagaaggtga ttttacaata ttcacaatgg aggagtgtaa
     7201 tgatattata aaagactaca ataataatga acttgtttta aataaaaaat taagattgca
     7261 atatactgta aaatcatgga tgaaaagcag tgaagtttat agacatggat acgaaaatac
     7321 tataataaac taaacaatag tgataaaata ataaatatat gtttaaattg gtatatattg
     7381 gataaatatc taaggaaaca acaattaaaa aataataatt ttaggggagg tattttagta
     7441 tgaaagcatt tgttgataag gatgtatgtg tagcttgtgg agcatgtata ggaacatgtc
     7501 cagacgtttt tagtatgagc gatgaagggc attcagtagc aattgaagga gaaataccag
     7561 cagacttaca agatttatgt aaagaagccg aagaaggatg tccagtttca gctataacag
     7621 ttaaatagag ctgtttaaat ttatttttaa aataaatata taagatttaa ttgggtactt
     7681 aagctatagt attagaaatt tctattacta tagcttttta aaatagataa acttaatata
     7741 taagatatta ctttttacaa atatggagga ctgaaatatg aaaaaaaatt atgaaatagt
     7801 attattcgat ttagatggaa cacttacaga ccctaaagaa ggaataacaa agtctattca
     7861 gtattcttta aatagctttg gcataaaaga agatttggaa aacttagacc aatttatagg
     7921 accaccatta catgatactt ttaaggagta ttataaattt gaagataaaa aaactaaaga
     7981 agctgttgaa aagtatagag aatattttgc tgataaaggg atatttgaaa ataaaatcta
     8041 tgagaatata aaagagatat tagaaatgct ctataaaaat ggtaaaatat tattagtagc
     8101 aacttctaag ccaacagttt ttgcagaaac tatacttaga tattttgata tagatagata
     8161 ttttaaatat atagcaggta gcaatcttga tggtacaaga gtgaataaaa atgaagttat
     8221 acaatatgta ctagacctat gtaatgtaaa agataaagat aaagttatta tggttggaga
     8281 tagaaagtat gacataattg gagccaaaaa aataggtata gattctattg gagtgttgta
     8341 tgggtatggt tcttttgaag aacttagtga aagtgaacct acttatattg tcgaaaatgt
     8401 agagtctata aaagatattt tgttataaat atcttttata gacaaaaata ttacaaaatg
     8461 gtgtcgcata tttaaaaata tgatattata gttaaggaag tcatttaaaa aagaggagga
     8521 tgcacttaaa atgaaatcta ttttaattat gggtggaagc gacttcatag gttctgcact
     8581 tgctaagcgc ttgattaaat gtgggtatca aattgatata cttacaaatg gtaaaaagga
     8641 aatagattat aatggtttta aagaacatct aatttgtgat agaaaagttc gaaaagatat
     8701 ggaaaacatt atcacaggaa gaaaatatga ttacatatat gatatgacag catatacaaa
     8761 agaagatgta agtaatctga ttgattttat aagtatggat aacttaaaaa agtatatagt
     8821 attgtcagca ggagcagtat ataaagatag tggaagaaat ataaaagaag aaaatgagaa
     8881 aggtgaaaat gaaaactggg gaaaatatgg gttaaataaa aaagaggctg aagattttat
     8941 tataaatagc cctataccat atataattat tagaccaact tatatatatg gtgaaaataa
     9001 taatttatat agagagtatt atttctttga aaaaatagaa aaaaatgaaa agataccagt
     9061 accaaaagga aaacaagtta gtaatcaatt tatatatatt ggggatttgg taaaggtatt
     9121 ggaaagcata atgaaaaatc ctcatgtaag agaggcctat aatgtgacaa atccacagtt
     9181 aatttcttgg gatgacctta tatatacatg tggagaaatt attggcaaag aacctataat
     9241 aaaatatgta gatatggaaa aagtagagtt tagagaaaga acgtatttcc catttagaaa
     9301 tatagacttt aatcttgata taaataagct tattgaacat gggctttata taccaaatgt
     9361 gttactaaaa gaaggtctta cagcaacata taaatggttt tcagcaaata agccaaaaat
     9421 gcatgacaga aaaatgaaca aagttgagtc tgtaatgcaa atagtttaaa aaaataaata
     9481 agtaggtaga tattttgaac tcaaaaatta agtatttttt aaaatttttt atcttaatat
     9541 ttattttgat ttttatatac tcagttgcga tagagccgag tctattaatt gtgaaaaaat
     9601 ataatataag tgaaaatgga acattgataa aaagtgatac aattgagagt aaatctgaaa
     9661 ggataaaagt agttcaaatt tcagatactc aaataggtag tttttattca actaagaatc
     9721 tcaaaaaagt agctaataag attaacactt tgaatccaga tataatagta tttactggtg
     9781 atttaattga ttactccaat aaaaatccaa gtgtagatga aattacaact attttatcaa
     9841 gtatgaatgc taggttggga aaattttcag tatttggcaa tcatgattat atgtataaac
     9901 ttcctaggta ttataggcag attatgaaaa attccaactt caatctttta gtaaatgaaa
     9961 ataaaaaaat aaaattaaaa gatgataaat atattaatat attaggtgtt gatgaaatat
    10021 taaatggaaa tcctaatata aaatatctgg agagtcaaat agataataag aattttaatt
    10081 tattgttagc acatgaacca gatttagtag atatgcttag taaagataca atgaatttag
    10141 ttctatctgg gcatagtcat ggtggtcaaa taagattacc tattaaggga gcattagtta
    10201 ctcctccata tggaaggaaa tatactaaag ggttttatga tataaatgga aatcatttat
    10261 atgtgagttc gggtcttgga agtacaaagt taccatttag attttttaat ataccagaga
    10321 taatagaatt taatattata atctaacata aaatatttag aaaatataat tttgcttttt
    10381 ataatatgta gatgtatata ctgtaaaaat ggattaaacc agtagattga atgaattaat
    10441 agattaaatt aatatataaa atatttaagt tataattaat gtattagaca aaataaatac
    10501 tattaag
//
LOCUS       DAMJVG010000110        10378 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.115, whole genome shotgun sequence.
ACCESSION   DAMJVG010000110 DAMJVG010000000
VERSION     DAMJVG010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10378)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10378)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10378
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.115"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            <1..1029
                     /locus_tag="PC512_003336"
     CDS             <1..1029
                     /locus_tag="PC512_003336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HDF2443056.1"
                     /translation="KKIKKLFLDDKGYYFNSNWKDIHIGIYNTKLGDSLKYITNEYIE
                     NLERVKYDYRELKNIENQTDGMCILAIRQNYKALEYVKNQTEELCLEAIKYNYKALEY
                     VKEQTEYICLEAIKKDCNALKYVRNKTERLIIKVIRHSSNIDVVSILKALETQTRRIC
                     LEAIKKDGRCLAYVREQSEELCIEAIKQNYKALKYVENQTEKMCIESVRQNGMALQYV
                     NKQTDKICIEAVKQDGRSLQFVNNKTEEICINAIRYLNKKYNIKDVLSYIDKYTEDIC
                     IEIVRQNGKMLMYIKNQTEKMCIEAVKENYKSLKYVKEQSERICKEALKQNHKAKEYV
                     KIAIDDCI"
     gene            1168..1620
                     /gene="tsaE"
                     /locus_tag="PC512_003337"
     CDS             1168..1620
                     /gene="tsaE"
                     /locus_tag="PC512_003337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HDF2443057.1"
                     /translation="MAKIYLENENKTREIGYKLGKLLKEGSVICLVGDLGAGKTTMTQ
                     SLADSLGIEDYITSPTFTIINEYEGKIPLYHFDVYRIGSSDEMYDIGYDEYVNSNGIC
                     IIEWANLIEDILPKEYLNIELRYKDDGREMILTPKGEFYKEIVEELIK"
     gene            1620..2336
                     /gene="tsaB"
                     /locus_tag="PC512_003338"
     CDS             1620..2336
                     /gene="tsaB"
                     /locus_tag="PC512_003338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HDF2443058.1"
                     /translation="MKILGMDTSSMAASVAVVEDDNLICEFTVNNKKTHSQKLMPMIE
                     NMLSMSDLSIKDMDLLAVCIGPGSFTGLRIGMATVKAMAHVNNIPIIAVNSLESLANN
                     INFCDRKICCILDAQKNQVYSAKYKFENGEMIELDGVDVVEFDALVDEIVSTNEEFII
                     VGEAVYKYKDKLENIKNIKIPSPANNVSNAGSLCSLALNKYNKNIDVHTCYTINPMYI
                     RKSQAEVQYDEKMKRLNNGR"
     gene            2326..2802
                     /gene="rimI"
                     /locus_tag="PC512_003339"
     CDS             2326..2802
                     /gene="rimI"
                     /locus_tag="PC512_003339"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HDF2443059.1"
                     /translation="MEDNTKLIVDDIKIEEMTTEDIDEVFEVEKNCFEDYWSKESFRK
                     ELSNEVARYIVAKLNGKIVGYVGIWLILDEGHINNVAVHSDYRGKKIGDKLIKGIVDL
                     CKDNNIASMTLEVRASNKIAQNLYRKYGFKMGGIRKEYYSDNKEDAIIMWNQLKEV"
     gene            2808..3824
                     /gene="tsaD"
                     /locus_tag="PC512_003340"
     CDS             2808..3824
                     /gene="tsaD"
                     /locus_tag="PC512_003340"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HDF2443060.1"
                     /translation="MSDIITLAIESSCDETAASVLKNGREVLSNIISTQIETHKKFGG
                     VVPEVASRKHVENIDIVVQEALDKANIGFNDIDHIAVTYGPGLVGALLVGLSYAKALA
                     YTLNIPLVGVNHIEGHLSANYIEHKDLKPPFITLIVSGGHTHLVEVKDYGKYEILGKT
                     RDDASGEAFDKISRAMNLGYPGGPIIDNLAKKGNKHAIEFPRAYLEEDSYDFSFSGLK
                     SSVLNYLNGKRMKNEEIVVEDVAASFQEAVVEVLSTKALKAVKEKGYNIITLSGGVAS
                     NSGLRAKITELAKDSGITVKYPPLILCTDNAAMIGCAGYYNFINGKTHDMSLNAVPNL
                     KINQ"
     gene            4121..6829
                     /gene="hpdB"
                     /locus_tag="PC512_003341"
     CDS             4121..6829
                     /gene="hpdB"
                     /locus_tag="PC512_003341"
                     /EC_number="4.1.1.83"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase large
                     subunit"
                     /protein_id="HDF2443061.1"
                     /translation="MSQSKEDKIRSILEAKNIKSNFQNKENLSEFNEKKASKRAEDLL
                     DVYYNTLSTADMEFPYWYNREYRKSDGDIPVVRRAKALKSAFSHMTPNIIPGEKIVMQ
                     KTRHYRGSFPMPWVSESFFVAQGEQMREEAKKLASNTADELTKFGSGGGNVTESFGNV
                     VSIAGKFGMRKEEVPVLVKMAKEWVGKSVEDLGFHYEKMMPDYDLKENLMSTLICMFD
                     SGYTLPQGREVINYFYPLNYGLDGIIEMAKECKKAVAGNASGDGLIGMDRLYFYEAVI
                     QVIEGLQTWILNYAKHAKYLESIETDLEAKKEYSDLVEILEHIAHKQPRTFREALQLT
                     YTIHIASVNEDAISGMSIGRFGQILYPWYEQDIEKGLITKEEVIELLELYRIKITCID
                     CFASAGVNGGVLSGNTFNTLSIGGLKEDGSTGANELEELLLEASMRCRTPQPSLTMLY
                     DEKLPEDFLMKAAECTKLGSGYPAWVNNSNGTTFMMKQFADEGMTVEEARAFALGGCL
                     ETSPGCWKQLTLNGKTYSIAGGAGQSAGSGVHFIANPKILELVLMNGKDHRMNIQVFE
                     PHNKPLDTYEEVIEVFKDYYKQAINVLERANNIELDIWRKFDTSIINSLLKPDCLDKG
                     QHIGNMGYRYNATLNVETCGTVTMVNSFAALKKLVYDDKAFTIEEMKDAILNNFGFKD
                     ALEVGNYSMADQVKVDKTGKYDAIYKACLDAPKYGNNDLYADNILKNYEVWLSKVCEE
                     AQSLYAKKMYPCQISVSTHGPQGAATLATADGRLSGTTYSDGSVSAYAGTDKNGVYAL
                     FESATIWDQAVVQNSQMNLKLHPTTIKGQQGTKKLLDLTRSYLRKGGFHIQYNVVDSE
                     TLKDAQKNPDNYRQLMVRVAGFTQYWCELGKPIQDEVIARTEYEGV"
     gene            6833..7090
                     /gene="hpdC"
                     /locus_tag="PC512_003342"
     CDS             6833..7090
                     /gene="hpdC"
                     /locus_tag="PC512_003342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase small
                     subunit"
                     /protein_id="HDF2443062.1"
                     /translation="MRKHSDCMNFCAVDATKGICRLSKQMINLDDAACPEIKVMPKCK
                     NCKNFVEANDEGIGKCVGLEKEDWVYSTLNAITCEGHVFNE"
     gene            7083..8033
                     /gene="hpdA"
                     /locus_tag="PC512_003343"
     CDS             7083..8033
                     /gene="hpdA"
                     /locus_tag="PC512_003343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase activase"
                     /protein_id="HDF2443063.1"
                     /translation="MSSQKQLEGMIFDVQSFSVHDGPGCRTTVFLNGCPLSCKWCANP
                     ESWTVRPHMMFSELSCQYENGCTVCHGKCKNGALSFNLDNKPVIDWNICKDCESFECV
                     NSCYYNAFKLCAKPYTVDELVQVIKRDSNNWRSNGGVTFSGGEPLLQHEFLHEVLLKC
                     HEVNIHTAIETSACVSNEVFNKIFNDIDFAFIDIKHMDREKHKEQTGVYNDLILENIS
                     NLANSDWNGRLVLRVPVISGFNDSDENISDIISFMHKNNLVEINLLPFHRLGESKWIQ
                     LGKEYEYSDKGDVDEGHLGELQDIFLDNGIACYVGHETAF"
     gene            8348..9310
                     /locus_tag="PC512_003344"
                     /pseudo
     CDS             8348..9310
                     /locus_tag="PC512_003344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112760.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
     gene            complement(9409..10212)
                     /locus_tag="PC512_003345"
     CDS             complement(9409..10212)
                     /locus_tag="PC512_003345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDF2443064.1"
                     /translation="MMILPLSSVAIAKFYTEGLNNDMYEFYSLIILFFLTYSLLIVLK
                     LLNLINNNEFIIINLILTFISSLSIIIYSSNKKNLYPIKNIKLGSLLIIYFMISVIVP
                     TSFILILQGSQPNYSGIIKFIFTPITSLTTIYIFFSEEYAWRGFLQNIFFNKFGKKLG
                     VIILGICWSLWHLPLIFTLYTPETPILGLILRSIHIVGISIFLGYLYIKTKNIWFCAI
                     IHILNNSAFLITNSKESTITYHDILIVSMVVLIFYVPFLFTKEYKNNLE"
BASE COUNT         4079 a         1065 c         1900 g         3334 t
ORIGIN      
        1 aaaaagataa aaaaattatt tttagatgat aaagggtatt attttaatag taattggaaa
       61 gatattcata ttggtattta taatacaaaa ttaggagatt ctttaaagta tatcactaat
      121 gaatatattg aaaatctgga aagggtaaaa tatgactatc gtgaattaaa aaatatagaa
      181 aatcaaactg atggtatgtg tattttagca ataaggcaga attacaaggc attagagtat
      241 gtaaaaaatc aaaccgaaga attatgttta gaagcaataa agtataatta taaagcactt
      301 gaatatgtaa aagagcaaac agaatatata tgtcttgagg ctataaaaaa ggattgtaat
      361 gcacttaagt atgtacgaaa taaaacagaa aggcttatta taaaagtaat acgtcattct
      421 tccaatatag atgttgtaag tatactaaag gctttagaga ctcaaacaag aagaatatgt
      481 ttagaagcaa ttaaaaaaga tggcaggtgt cttgcatacg ttagagaaca gagtgaagaa
      541 ttatgtatag aggccattaa acaaaattat aaagcattaa aatatgtaga aaatcaaacg
      601 gaaaaaatgt gtatagaatc cgtaagacaa aatggtatgg cattacaata tgtaaataaa
      661 caaactgata aaatatgtat agaagctgtc aaacaagatg gaagaagtct acaatttgtc
      721 aataataaga cagaagaaat atgtataaat gctataagat atttaaataa aaaatataat
      781 attaaagatg tactaagtta catagataag tatacagaag atatatgtat agagattgta
      841 agacaaaatg gaaaaatgct tatgtatata aaaaatcaaa cagaaaaaat gtgtattgaa
      901 gcagtaaaag agaactataa gtctcttaag tatgtaaaag agcaatctga gagaatatgt
      961 aaagaagcat tgaagcaaaa ccataaagca aaagagtatg taaaaattgc tattgatgat
     1021 tgtatataag gtgtagatac agccatcaat agtgaaagat aaaaaaagat aaagacaagt
     1081 actttataat aatctaggct tatactataa ttaattaagc agtgatataa attcacatga
     1141 cgattatatc aaaatggaga tgaattgatg gcaaaaatat atttagaaaa tgaaaataaa
     1201 actagagaaa taggatataa attaggtaaa cttttaaaag aaggcagtgt tatctgttta
     1261 gtaggagatt taggagctgg taaaactaca atgacacaaa gcttggcaga ttcattaggg
     1321 atagaagatt atataacaag tcctactttt actataataa atgaatatga aggaaaaata
     1381 cctttgtatc attttgatgt ttatagaata ggtagtagtg acgaaatgta tgatattggt
     1441 tatgatgaat atgtaaattc aaatggaatc tgtataatag aatgggctaa tctaatagaa
     1501 gatatacttc caaaagaata tttgaatata gaattgagat ataaagatga cggaagagaa
     1561 atgatattaa ctccaaaagg agagttttat aaagagatag ttgaggagtt gattaaataa
     1621 tgaaaatact aggtatggat acgtcttcta tggcagcaag tgtagcagtt gttgaagatg
     1681 ataacttaat atgtgagttt acagtaaaca acaaaaaaac tcattcacaa aagcttatgc
     1741 caatgataga aaatatgttg agtatgagtg atttaagtat aaaagatatg gatttattag
     1801 ctgtatgtat aggtccaggc tcgtttactg gacttagaat aggtatggcc acagtaaaag
     1861 ctatggctca tgtaaataat ataccaataa tagcagtaaa ttctttggaa tctctagcaa
     1921 ataacataaa tttctgtgat agaaagatat gttgtatatt agatgcgcag aaaaatcaag
     1981 tttattcagc taaatacaag tttgaaaatg gagagatgat agaattagat ggtgtagatg
     2041 ttgtagagtt tgatgcttta gtagatgaaa ttgtatcaac taatgaagaa tttataatag
     2101 ttggagaagc tgtatacaaa tataaagata agttagagaa tataaaaaat ataaaaatac
     2161 cttcaccagc taataatgta tctaacgcag gaagcttatg ctctttagca ttaaataaat
     2221 ataataaaaa tatagatgta catacttgtt atacgataaa tcctatgtat atcagaaaat
     2281 ctcaagctga agtacaatat gatgaaaaaa tgaagaggct aaataatgga agataataca
     2341 aaactaatag tagatgatat aaaaatagaa gaaatgacta cagaagatat agatgaagtt
     2401 tttgaagtag aaaaaaattg ttttgaagat tattggtcaa aagagtcttt tagaaaagag
     2461 ttgtctaatg aagtagcaag gtatatagta gctaagttaa atggaaaaat tgtcggatat
     2521 gtgggaattt ggcttatact tgatgaaggg catataaata atgtggctgt tcatagtgac
     2581 tatagaggga aaaaaatagg ggacaagttg ataaaaggca tagttgattt atgtaaagat
     2641 aataatattg catctatgac attagaagtt agagcatcaa ataaaatagc acaaaattta
     2701 tatagaaaat atggatttaa aatgggtgga ataagaaaag aatactacag tgataataaa
     2761 gaagatgcaa ttataatgtg gaaccaatta aaagaggtgt agagtttatg agtgatataa
     2821 taacattagc tatagagagt agttgtgacg aaacagctgc atcagtttta aaaaatggta
     2881 gagaagtact ttcaaacata atctctactc aaatagagac acataaaaaa tttggtggtg
     2941 tagttccaga agtggcttca agaaaacatg tggaaaatat tgatatagtt gttcaagaag
     3001 ctttagacaa agcaaatata ggttttaatg atatagacca tatcgcagtt acatatggac
     3061 ctggactagt aggtgcttta ttggttggtc tatcttatgc taaagcactt gcatatactt
     3121 tgaatattcc acttgtagga gtaaatcata tagaagggca tctaagtgca aactatatag
     3181 agcataagga tttgaaacct ccttttataa cattaatagt atctggaggt catactcact
     3241 tggttgaagt aaaagattat ggcaagtatg aaattttagg aaaaacaaga gatgatgcat
     3301 ctggagaagc attcgataaa atttcaagag caatgaattt aggttatcca ggaggaccta
     3361 ttattgataa tctagccaag aagggaaata aacatgctat agagtttcca agagcctatt
     3421 tagaagaaga tagttatgat tttagtttta gtggattaaa atcttctgta ttgaattatc
     3481 taaatgggaa aagaatgaag aatgaagaaa tagtagttga agatgtagca gcatcttttc
     3541 aagaggctgt ggtagaggtt ttatctacta aggcactaaa agcagtaaaa gaaaaaggat
     3601 acaatatcat aactctttct ggtggagttg cttctaattc ggggcttaga gctaaaataa
     3661 cagagcttgc taaagacagt ggtattactg ttaagtatcc tcctctaatt ttatgcacag
     3721 ataatgcagc tatgataggg tgtgcaggat attataattt tataaacggg aaaacgcatg
     3781 atatgagttt aaatgcagtt ccaaatttaa agataaatca gtagagttag ataaatttgt
     3841 aaatataaaa gtattgtttc aaaaaagtaa gcagaagtga aattaaatat aataaaaatc
     3901 aatatagtat atattaaaac ttgaagtaaa actatttata atctttatat tccaatgaat
     3961 tgcaacacat tttaggatat acaggttgtc tttggcttag atttgcttca agtttaattt
     4021 tttctataga aagattattt taaaaagtgg gtaatatacc cttttttttc attcttaaaa
     4081 agttttatac taattataga aagattaagg aggggaagaa atgagtcaaa gtaaagaaga
     4141 caaaataaga agtattttgg aagcaaaaaa tatcaaatca aattttcaaa ataaagaaaa
     4201 tttaagtgaa tttaatgaaa aaaaagcaag taaaagagca gaagacttat tagatgtata
     4261 ttataataca ttatctactg cagatatgga atttccatat tggtataata gagaatatag
     4321 aaaatcagat ggtgatatac cagtagttag aagagctaaa gctcttaaat ctgctttttc
     4381 acatatgaca ccaaatataa tacctggtga gaaaatagta atgcaaaaga cacgccatta
     4441 tagaggttct tttccaatgc catgggtaag tgaaagtttc tttgttgctc aaggagaaca
     4501 aatgagagaa gaggcaaaga aattagccag taacacagct gatgaactta caaaatttgg
     4561 gtctggcgga ggaaatgtta ctgaaagttt tggaaatgtc gtttcaatag ctggtaaatt
     4621 cggaatgaga aaagaagaag tacctgtact tgtaaaaatg gcaaaagaat gggttggaaa
     4681 gtctgttgaa gatttaggtt ttcactatga aaaaatgatg ccagattatg atttaaaaga
     4741 aaacctaatg agtacactta tatgtatgtt tgattcagga tatacacttc ctcaaggtag
     4801 agaagttata aattattttt atcctttaaa ttatggatta gatggaatta tagaaatggc
     4861 aaaagaatgt aaaaaggcag ttgcaggaaa tgcatctgga gatgggctta ttggtatgga
     4921 ccgtctatat ttttatgagg ctgttattca agttattgaa ggattacaaa cttggatttt
     4981 aaattatgca aaacatgcaa aatatttaga aagtatagag acagatttag aagctaaaaa
     5041 agaatactca gatttagtgg agatattaga acatattgca cataaacaac ctcgtacatt
     5101 tagggaagct cttcagttga cttatacaat tcatatagca tcagtaaatg aggatgctat
     5161 atctggtatg tctataggcc gttttggtca aattttatat ccttggtatg aacaagatat
     5221 agaaaaagga ttaattacaa aagaagaggt tatcgaatta ttagagcttt atagaataaa
     5281 aatcacttgt attgactgtt ttgcttcagc gggcgtaaat ggaggagtac tatcaggaaa
     5341 tacatttaat actttatcta taggtggatt aaaagaagat ggttctacag gagctaatga
     5401 actagaggag ttattattag aagcaagtat gagatgtaga actcctcaac ctagtttaac
     5461 tatgttatat gatgaaaaac ttccagaaga tttcttaatg aaagctgctg aatgtacaaa
     5521 gcttggttct ggttatccag cctgggtaaa caactcaaat ggaacaacat ttatgatgaa
     5581 acaatttgct gatgaaggta tgactgttga agaagcgaga gcatttgcat taggaggatg
     5641 tttggaaacg tctccagggt gctggaaaca gttaacttta aacgggaaga catactctat
     5701 tgcaggtgga gcaggtcaat ctgctggctc tggagttcac tttatagcta atcccaaaat
     5761 tttagaactt gttcttatga atggtaaaga ccatcgtatg aatatacaag tatttgagcc
     5821 tcataataag ccattagata cttatgaaga agtcatagaa gtatttaaag attattataa
     5881 acaagcaata aatgttttag aaagagcaaa taacattgag ttagatatat ggagaaaatt
     5941 tgatacttct ataataaatt cactattaaa gccagactgt ttagacaaag gtcaacatat
     6001 aggaaatatg ggatatcgtt ataatgcaac attaaacgta gaaacttgtg gtactgttac
     6061 tatggtcaat tcatttgcag cacttaagaa acttgtatat gatgacaaag catttacaat
     6121 agaggaaatg aaggatgcca tattaaataa ttttggattt aaagatgcat tagaagtagg
     6181 aaattattct atggcagacc aagtaaaagt agataagact ggtaaatatg atgctattta
     6241 taaggcctgt cttgatgcac ctaaatatgg aaataatgat ttgtatgcag ataatattct
     6301 taaaaactat gaggtatggt tatcaaaagt atgtgaagaa gcacaatctt tatatgctaa
     6361 gaagatgtac ccttgccaaa tatctgtttc tacacatgga ccacagggag ctgctacctt
     6421 ggctactgca gatggtagac taagtggaac aacatattca gatggttcag tctctgcata
     6481 tgcaggaaca gataaaaatg gggtatatgc attatttgaa tctgcaacta tttgggacca
     6541 agcagtagtt caaaattctc agatgaattt aaaacttcat ccaacaacta taaaagggca
     6601 acaaggaact aaaaaattat tagatttaac aagaagttat ttaagaaaag gtgggttcca
     6661 tattcaatat aatgttgtag attcagaaac attaaaagat gcacaaaaaa atcctgacaa
     6721 ttatcgtcaa ttaatggtac gtgttgctgg gtttactcaa tattggtgtg aattaggtaa
     6781 accaatacaa gatgaagtaa ttgctagaac agagtatgaa ggggtgtaaa atatgagaaa
     6841 gcatagtgat tgtatgaatt tttgtgcagt agatgcaacc aaaggaattt gtagattatc
     6901 aaaacaaatg attaatttag atgatgcagc atgtccagag ataaaagtaa tgccaaaatg
     6961 taaaaattgt aaaaattttg ttgaagctaa tgatgaaggt ataggcaaat gtgttggcct
     7021 agagaaagaa gactgggtat attcaacatt gaatgcaatt acttgtgaag gacatgtgtt
     7081 taatgagtag tcaaaagcaa ttagaaggca tgattttcga tgtacaaagc ttttcagttc
     7141 atgatggtcc aggttgtaga acaactgtat ttttaaatgg atgtccactg agttgtaaat
     7201 ggtgtgcaaa tccagaaagt tggactgtaa gaccacatat gatgtttagt gaattatctt
     7261 gtcaatatga aaatggatgt actgtatgtc atggtaagtg taaaaatggt gcattgagct
     7321 ttaatcttga taataagcca gttatagatt ggaacatctg taaggactgt gaaagttttg
     7381 aatgcgtcaa ctcatgttat tataatgcgt ttaaattatg tgcaaaacct tacactgtag
     7441 atgaacttgt gcaggtaatt aaacgtgatt ctaacaattg gagaagtaat ggaggagtaa
     7501 catttagtgg aggtgagcca ctacttcagc atgaattttt acatgaagta ttattaaagt
     7561 gtcatgaggt aaatatacac actgccattg aaacgagtgc atgtgtatca aatgaagttt
     7621 ttaataaaat atttaacgat attgattttg catttattga tataaagcat atggatagag
     7681 aaaaacacaa agaacaaaca ggtgtgtata atgatttaat attagaaaat atatcaaacc
     7741 ttgcaaattc tgattggaat ggaagattag tacttagagt accagttatc tctgggttta
     7801 atgatagtga tgaaaatata agtgatatta tatcttttat gcacaaaaat aatttggtag
     7861 aaattaatct attaccattt cacagattag gagaatcaaa atggattcaa ttaggcaagg
     7921 aatatgagta ttctgataag ggtgatgttg atgaaggtca tcttggagaa ttacaagata
     7981 tatttttgga taatggtata gcttgttatg ttggtcatga gacagctttc taaaattaaa
     8041 tacaagtttt aattaaaaaa ggatgttaca ctaaaagcta gagttacatc cttttttatg
     8101 tggtttttat gtagaaataa ttaagtaaag ttttatatat tttatatatt gtttatattg
     8161 ctttatgtcc ataaatattg ctttaaatat actttatata ttttttatag tttaaattac
     8221 agttagagaa tatattacgt ttactttatt gaagcagaag ttttgtggta aaatactact
     8281 atgaaaaaat ttaatagaat atattttaga aacaactaaa aataatagtt aggaggaaga
     8341 catctatatg aacaaatcat ggagcaactt gattattaag aataaagaca aaaaagtacg
     8401 ttcagggtgg attattatag ctgttatggc taccttttac atatttcagt attatttaag
     8461 catgatactt gtggaaataa taagaaaaat cctggttgct acaggggaca ttaatttaaa
     8521 aacaaactat ttttcagaat atgctaattg gttaaatgat gttgggttac agattgtatt
     8581 tcaaattcta acagattcac ttatgattat tattcctata attgtatgga gatttattat
     8641 gaaaaatcct attagtgaaa tgggattaca ttcttataga attaagaaaa aagaaggata
     8701 tgtaggaatg ttattaggaa tatttaattg tacagtaatc tttattataa caataacaat
     8761 tggtggtggt catgttactt catgggtacc aaaaatttca cctttaacag tttcttgaat
     8821 acttgtcttt attttagttg cttttgcaga agaaatttta aatcgtggtt tttttatggc
     8881 agttttacga agatgtaaaa atatttattt tataatgatt gttccatctg ttatttttgg
     8941 gttgattcat atatggaatc ctgatgttac ttttttgtct gtaattaata ttataattat
     9001 tgggattctt ttttcatata tgtttataaa gtcgtcgaat atatggatgt gtataggtta
     9061 tcattttaca tggaatgtat ttcaggggat tatatatggt atgcctgtaa gtggacttca
     9121 ggttccaggg attataacta cacaaatcac tcatggtaat ctattaaatg gtggtatgtt
     9181 tggtattgaa ggtggaattt tgactacttt tgttaatcta cttagtttta tatttgtatg
     9241 gtattactat agagattcta agtatgattt tgttagtgat aaagtaaatg tgaccaatat
     9301 caagaattag ttgattataa taaattttaa taatatcttc taagcttaaa gtattctgta
     9361 ggattgttgg aaatttacaa aaatataaaa ataacttgga tattctattt actccaagtt
     9421 atttttatat tcttttgtaa atagaaatgg aacataaaaa attaaaacaa ccatagatac
     9481 tattagtata tcatggtaag tgatagttga ttctttagaa tttgtgataa gaaaagcact
     9541 attatttaaa atatgaatta tagcacaaaa ccagatgttc ttagttttta tataaagata
     9601 tcctaaaaat attgaaattc caactatatg tatcgaacgt aatattaatc ctaatattgg
     9661 tgtttcaggt gtatataatg taaatattag tggtaagtgc cacaaactcc aacaaatacc
     9721 taatattata actcctagtt ttttaccaaa tttattaaaa aaaatattct gtaaaaaacc
     9781 tctccaggca tattcttcac taaaaaaaat ataaatagta gttaatgatg ttattggagt
     9841 aaatataaat tttatgatac cactataatt aggttgagac ccttgtagta ttaatataaa
     9901 tgatgttgga acaattacag aaatcataaa gtaaataatt aacaaagaac ctagtttaat
     9961 attttttata ggatataaat tttttttatt tgatgaatat attataattg ataaactact
    10021 tataaaagtt aatattaggt ttataattat aaattcatta ttatttatta gatttaataa
    10081 cttaagaaca attaataacg aataagtaag aaaaaatagt atgattagtg aataaaattc
    10141 atacatatca ttatttaatc cttcagtata aaattttgca atagcaactg aagatagagg
    10201 taatatcatc atgaatgatg caaagttttc tggatcaata aatttattat aatacaataa
    10261 taaacctaat gaataagtta aaccaaagtt tataaagaaa aatataataa tttgtacttt
    10321 ttttcttttt atttcatttt taataagtat tggatttaga atatttatcc atattaat
//
LOCUS       DAMJVG010000111        10240 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.116, whole genome shotgun sequence.
ACCESSION   DAMJVG010000111 DAMJVG010000000
VERSION     DAMJVG010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10240)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10240)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10240
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.116"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            <1..922
                     /locus_tag="PC512_003346"
     CDS             <1..922
                     /locus_tag="PC512_003346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF2443065.1"
                     /translation="NSIYFVPLILDISFLIKEKYKYILFSFVIISSLIISLDKNIYLA
                     LESSSILLIITVLSIYIENENLSKLYSQNLYDKLRISKDELKKVNADLETYASSIEEL
                     AILKERNRISREIHDSVGHSLSTTIIQLNAIEKLLKDKPLIYDLVHELREFVTESFQD
                     VRRAISELKPVEYENYQSLFKIKELVKSFIKLTNINVKLTISKNTWNLSRNQSITLYR
                     LIQESLSNSSRHGKATEIRIFITFNTSNLIITISDNGIGCGNIKKGNGLNSINERIYE
                     LNGKVEFDNSNNGFTIRASFPKFSGGDFFE"
     gene            915..1562
                     /locus_tag="PC512_003347"
     CDS             915..1562
                     /locus_tag="PC512_003347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2443066.1"
                     /translation="MNKIKVLIVDDEKLIRKGLKIILSSYNDLEIVGDASNGYEALEF
                     CKMNDVDIVLMDIRMKVCDGVLGTRLIKEYNNSITLLILTTFNDDEYIKDAMKFGASG
                     YLLKDSSDEVLHEGIRSSFFGNIVLDKSVAEKIMTSEKTVKQEHLYDMYNLTEKEISI
                     IRLIANGLNNKEISQELFLSEGTIKNNITNILAKLELRDRTQLAIFAFKNKIVIE"
     gene            1691..2626
                     /locus_tag="PC512_003348"
     CDS             1691..2626
                     /locus_tag="PC512_003348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2443067.1"
                     /translation="MDIVRVNNITKRFNDKLVLDNISFSVKKGEIFGLIGPNGAGKST
                     LINIITNLMLPNSGSIQINGLDLSKDYIKAKSIIGLVPQELAIIETLTPFDNLEYFGA
                     FYGLKGKLLKERIIEALEVTGLTEVKKKKVKKLSGGMQRRLNIGIALLNHPKILILDE
                     PTVGVDPQSRNHIFNFIKDISKKHETTVIYTSHYMEEVEHLCSKIFIMDEGKEIAFGD
                     NDYLKSLVSTNTKLIIEIKNINAQLIFDLKNTKGVISVLENNSLLELDIDKKLQLTDI
                     LSVIDKNNSKIMKISYEEPSLEDVFLNLTGKNLRD"
     gene            2640..3737
                     /locus_tag="PC512_003349"
     CDS             2640..3737
                     /locus_tag="PC512_003349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2443068.1"
                     /translation="MKLYMSVKTMLKSLKSSFILNLIYFLALPLILSWFLGMVTESMF
                     QNPIKTESTPIVIYDKDNTRLSNDLTKYLKNDLSYILTVKKDDSKAELKLTIPKGYES
                     SLLNEKSNTLNIEKLGTRDDIAILLQDILDTYHEKFYLNNSQKISSEDFSKLFNKNSI
                     DTSIINNNVKQNSYEYFALVSLGFLVIIFIMNNILSNYISESKGLSKRLYSMPITRVQ
                     FLIYDFVGLWIYSFIFLLLYVLFFRILGITFKGNFAILLLLCALSSYFMTSISTFVTS
                     FFSKKYGTAIVYALLFLQTIFGGIFSMISDTFTKLTSLSPTYLIGELFSNYETFKTID
                     SIGDLIFTCLIISTILIALAIVKEKYKWREV"
     gene            3740..4804
                     /locus_tag="PC512_003350"
     CDS             3740..4804
                     /locus_tag="PC512_003350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2443069.1"
                     /translation="MIRLTIANIKRYLKNHNLLINMVMLPIILIFSLNFFINNSGNQS
                     MYFSPVAIVSDSSGKYEHKLINSSKLKENSFRLNELDKAMNLLKNNKVSAVFVLDKNF
                     SNSIDKLQRPVVKCFKIENGGGSLWAESQIESFITKSLKLKVDKNIDDKLTKTNIIDN
                     KPDKNKGSFLVVFLICYFMYINAAHLASDLFTLKKSNVLKRLISTDNKDIKIIFSIFL
                     GLFFIQSIVYTFALLCFSIIEDFNLSLNVLMIVLANSFVSTGFVFWVARVFKNESSIS
                     LISTFYSLIGLAISISSLIPSMDKLSFMTNLSKFTPFYWTIDAIKNNGSILINIIALI
                     LIGIIFVTAGSLKLRDFAKN"
     gene            5048..5545
                     /locus_tag="PC512_003351"
     CDS             5048..5545
                     /locus_tag="PC512_003351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CarD family transcriptional regulator"
                     /protein_id="HDF2443070.1"
                     /translation="MYKIGESVMYPKEGACSVNDIVTKKINHEMQKYYELSVIFNSNL
                     KISIPVLNADRIGIRPVMDGNDVDNFIQSINKTDGVWIFDRKERLKLYQDKFHSGDVF
                     EIVKLIKMLMIQDSSKQLCSTDKEFLNKAQKFALSELAAAQCKSYTMVLEEMKKHILN
                     SKNTN"
     gene            complement(5721..5969)
                     /locus_tag="PC512_003352"
     CDS             complement(5721..5969)
                     /locus_tag="PC512_003352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443071.1"
                     /translation="MSRKAYEEALVELEKFIDERKEIIKSAEDCIDKYIVDRTLPFDY
                     KDKCVEWQQELLDIAEAQVLEANELSVLLQEKKELEED"
     gene            complement(6035..7051)
                     /locus_tag="PC512_003353"
     CDS             complement(6035..7051)
                     /locus_tag="PC512_003353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HDF2443072.1"
                     /translation="MEYNELLKSARENLNGSCKVCKVCNGVACAGEVPGMGGKGSGSS
                     FIENSKSLEKVKVNMRVIHDVSNPDTSIEMFGKKMSAPIFAAPVTGTTLNMGGKINER
                     DYIEPVVAGCANSGIYAMVGDTAVDAFLMENLDVVKKYNGAGIVFIKPWDNENIIKKI
                     RLAEEAGAFAVGVDIDACGLVTLSLHGKPVLPKNVKQIKELVKSTKLPFILKGIMTVE
                     DALMAVEAGVDAIVVSNHGGRVLDCTPGACEVLPKIADAVKGKVTILADGGVRTGLDV
                     LKMIGLGADAVLIGRPFVTASFGGATDGVETYVNKLQSELSSSMILTGCQTIKDIDGK
                     VIYK"
     gene            complement(7109..7876)
                     /locus_tag="PC512_003354"
     CDS             complement(7109..7876)
                     /locus_tag="PC512_003354"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HDF2443073.1"
                     /translation="MQDKSVREIKEIIETLEVEKYMEYIELLRVDERKSVQGLAIKLA
                     KKLDNIRKEEERLETINIFENEGYDKGYLYIGGIDEAGRGPLAGPVVASVVVFKKDTK
                     IEGVNDSKKLSEAKRDELFEVIKEEALDYGIGIVNNEEIDEFNILNATYMAMKKAINC
                     LKKAPDYLLVDAATIPGIDISQNPIVKGDSKSISIAAASILAKVTRDSIMYQYDRVYP
                     EYGFKSHKGYGTKEHYEAIEKYGITPIHRKSFLKNIL"
     gene            complement(7944..10133)
                     /locus_tag="PC512_003355"
     CDS             complement(7944..10133)
                     /locus_tag="PC512_003355"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobalamin-dependent
                     ribonucleoside-diphosphate reductase"
                     /protein_id="HDF2443074.1"
                     /translation="MKYIIKRDGTKELFSKSKIEDAVYKASINSEGGVDRELAYDISR
                     KIANDYNSMEKCLSVEEIQDIVEVLLMESNRKDIAKHYILYRERRSEIRTKAWEFDEL
                     QKSIWKNKYRHNGESFDEWIKRISNNSSRISKLIRQKRFLFAGRILANRGLQKEGKKV
                     TYSNCYVIEPPKDSIEDIFDTAKKLARTFSYGGGVGIDISKLRPKGAKVNNAAKHTTG
                     AVSFMELYSMTTGLIGQRGRRGALMISMDVNHPEIEDFIDIKTDLEKVTKANISVRVT
                     DEFMQAVREKKLYNCTFEVETTGEKIVKIVNAYDLFNKFVKNNWDYAEPGILFWDKIK
                     TYNFMSEDKNFCFSGVNPCAEEPLPSGGSCLLGSINLSEFIIQPFGEHATFDINKLKS
                     CVREAVVALNDVLDEGLNLHPLQEQRDSVHKYRQIGLGVMGIADMLIKMGIRYGSDES
                     LELCDLIGKTMLNEAVKQSALIAKEYGTFSEYKYENISKSKFFIENLNEDTKEMVKKY
                     GLRNSQLLTIPPTGSISTMIGISGGIEPIFNLSYIRKTESLHDEDVYYKVYTPIVKEY
                     MDKKGITDEECLPDFFVTAMNIGYEERINMQKVWQKYIDASISSTINIPFETTVEDVF
                     NIYIKAWEAGLKGVTIFRDGCKRSGILINEKKEENNKEDKKENSKKEYYKNNKKEKDN
                     KDEKAKEIINKNFEEDEKFVCPECGSEGIAHTGGCSICLKCGYSGCN"
BASE COUNT         3561 a         1570 c         1186 g         3923 t
ORIGIN      
        1 taattcgatt tactttgttc ctttaatatt agatatatca tttttaataa aggaaaaata
       61 taagtacata ttgttctctt ttgttataat atcttctctt attattagtt tagataaaaa
      121 tatatatttg gcactggagt caagctctat attgctaatt ataactgtac tttctatata
      181 tatagaaaat gagaatttat caaaattata cagtcaaaat ctttatgata agcttagaat
      241 ttctaaagat gaattaaaaa aagttaatgc tgatttggaa acttatgcaa gttctataga
      301 agaattagca attttaaaag aaagaaatcg aatatcaaga gaaatacatg atagtgtagg
      361 acattctctt tctacaacaa taatacaatt aaatgctata gaaaaactct taaaagacaa
      421 acctctaatt tatgacttag tacatgaact tagagaattt gtaactgaaa gttttcaaga
      481 tgtaagaagg gctatatctg agttaaaacc tgttgaatat gaaaattacc aaagtttatt
      541 taaaatcaaa gaattagtta aaagctttat taagcttaca aatattaatg ttaaattaac
      601 tatttcaaaa aatacttgga acttatccag aaatcaatct ataactttat atagacttat
      661 acaggaatcc ctttccaact catctaggca tggaaaggca actgaaatca gaatttttat
      721 tacattcaat acttcaaatc ttataattac tattagtgat aatggtatag gatgtggcaa
      781 tataaaaaaa ggaaatggac ttaatagtat caatgagaga atatatgaat taaatggtaa
      841 agttgaattt gataattcta ataatggttt cacaattaga gcttcttttc ctaaattttc
      901 agggggtgat ttttttgaat aaaattaaag ttcttatagt agatgacgaa aaattaatta
      961 gaaaaggtct taaaattata ttatcatctt ataatgattt agaaattgta ggagatgctt
     1021 ctaatggata tgaagcttta gaattttgta aaatgaatga tgtagacata gttcttatgg
     1081 atatacgaat gaaagtatgt gatggggttc taggtacaag gcttataaag gaatataata
     1141 attctataac attattaatt ttaacaactt ttaatgatga tgaatatata aaagatgcta
     1201 tgaagtttgg tgcttcagga taccttttaa aagatagctc tgatgaagta ttgcatgaag
     1261 ggattcgttc ttcatttttt ggcaatattg tgcttgataa aagtgtagct gaaaaaatca
     1321 tgacctctga aaaaacggtt aaacaagagc atctttatga catgtacaat ttaacagaaa
     1381 aagaaatatc tataattaga ctaattgcaa atggacttaa taataaagaa ataagtcaag
     1441 aactattctt atctgaaggt acaataaaga ataatataac taatatttta gctaaactag
     1501 aacttcgtga cagaactcaa ctagcaatct ttgctttcaa aaataaaatt gtaatagaat
     1561 aaatctaaaa atataaagtg acttaagtca ctttttttag tgacttatag taatagaatt
     1621 ataattcaca attctttatt ataatattat agctttttaa cttatacaaa attattttgg
     1681 agggattact atggatatag tcagagtaaa taatataaca aaaagattta atgataaatt
     1741 agtacttgat aacatcagct tttctgttaa aaaaggtgag atatttggac ttattggccc
     1801 aaatggtgca ggtaaatcta cacttataaa tataattaca aatcttatgt taccaaatag
     1861 tggtagtatt caaatcaatg gtttagattt atcaaaagat tatataaaag caaagtctat
     1921 aatagggtta gttccacaag aattagcaat tatagaaact cttactcctt ttgataactt
     1981 agagtacttt ggagctttct acggtttaaa gggaaaacta cttaaagaaa gaatcattga
     2041 agcattagaa gttacaggtc ttactgaagt caaaaagaaa aaggtcaaaa aattatctgg
     2101 tggtatgcaa aggagattaa atattggaat agcactctta aatcatccta aaatattaat
     2161 attggatgaa ccaactgtag gtgtagaccc ccaatcaaga aatcatattt tcaattttat
     2221 aaaagatata tctaaaaaac atgaaactac tgtaatatat acttcccatt atatggaaga
     2281 agttgaacac ctttgttcta aaatttttat tatggatgaa ggtaaagaaa ttgcttttgg
     2341 agataatgat tatttaaaat cactcgtatc tacaaataca aaattaatta tagaaataaa
     2401 aaatataaat gcccaactta tctttgattt aaaaaatact aaaggtgtta tatctgtttt
     2461 agaaaataat tcattattag aattggatat agataaaaaa ttacaactta cagatatact
     2521 ctctgttatt gacaaaaaca attcaaaaat aatgaaaatt tcttatgaag aacctagcct
     2581 agaagacgta tttttaaatc taacaggaaa aaatttaagg gactaatgga ggtgatttta
     2641 tgaaattata catgagtgta aaaactatgc taaagagttt aaaaagctcc tttatactta
     2701 atttaatata ttttttagct ttgcctctga ttttatcttg gtttcttggg atggttacag
     2761 aaagcatgtt tcaaaaccct ataaaaacag aatctacccc cattgttata tatgacaaag
     2821 ataacacaag attatcaaat gatttgacaa agtatttgaa aaatgattta tcttatatat
     2881 taacagttaa aaaagatgat tctaaggcag aattaaagct tactatacct aaaggctatg
     2941 agagtagttt attaaatgaa aaatcaaata ctctaaacat agaaaaactt ggaactcgtg
     3001 atgatattgc aatattgctt caagatatat tagatactta ccatgaaaaa ttttatttaa
     3061 ataattctca gaaaataagt tcagaagatt tttctaaatt atttaataaa aattctattg
     3121 atacttctat aataaataac aatgttaaac agaactctta tgaatacttt gctttagttt
     3181 cactaggatt tcttgtaata atttttataa tgaacaatat tttgtcaaat tatataagtg
     3241 aatcaaaggg actttcaaaa agactttatt ctatgcctat aactagagta caattcttaa
     3301 tttatgactt tgtaggttta tggatttatt catttatatt cttattatta tatgttttat
     3361 tctttagaat acttggaata acatttaaag gtaattttgc catattgctc ctactttgtg
     3421 ctttatcatc ttattttatg acttcaatat ctacctttgt aaccagcttt tttagtaaaa
     3481 aatacggtac agcaatagtt tatgcattac tctttttaca gacaattttt ggaggtatct
     3541 tcagtatgat aagtgataca tttactaagc ttacaagttt atctcctacc tatttaatag
     3601 gagaattgtt tagtaattat gaaacattta aaactataga ttcaatagga gatttaattt
     3661 tcacatgttt aattatctct acaatattaa ttgcacttgc tattgtaaag gaaaaatata
     3721 aatggaggga ggtttaataa tgattagatt aactattgca aatataaaaa gatatctaaa
     3781 aaatcataat cttttaatta atatggttat gcttcctatt atactaattt tttcacttaa
     3841 tttttttatc aacaactcag gaaatcaatc aatgtacttt tctccagtag caattgtatc
     3901 tgactcttca ggaaagtatg aacataagtt aataaatagt tctaaattaa aagaaaattc
     3961 atttagatta aatgaactag ataaggctat gaatctatta aaaaataata aggtttctgc
     4021 tgtattcgtt ttagataaaa atttttcaaa tagtatagat aaattacaac gacctgtagt
     4081 taaatgcttt aaaattgaaa atggtggtgg tagtctttgg gcagaatcac aaatagaatc
     4141 ttttattact aaatcgttaa aattgaaagt ggataaaaat atagatgata aattgacaaa
     4201 gacaaatata attgataaca aaccagataa gaataaaggt tcatttttag tagtcttctt
     4261 gatatgctat tttatgtata ttaatgcagc acatcttgct tctgatttat ttacattaaa
     4321 aaaatcaaat gtgctaaaaa gacttatctc tacagataat aaagatataa aaataatttt
     4381 cagtatattt ttaggactat tttttattca atcaattgta tacacttttg ctctattatg
     4441 tttttcaatt atagaagact ttaatttgag tctgaatgta ttgatgattg tactagcaaa
     4501 tagttttgtt tccactggat ttgtattttg ggtagctaga gtatttaaaa atgaaagttc
     4561 tataagtctt atatctacat tttattcttt aataggtcta gctatatcta tctctagtct
     4621 aataccatca atggataaat tatcctttat gactaatctt tcaaagttca caccatttta
     4681 ttggactata gatgctatta aaaacaatgg tagtatttta ataaatataa tagctctaat
     4741 attaattgga attatatttg taactgcagg aagtcttaaa ctaagagatt ttgctaaaaa
     4801 ctaataatta ttaaatataa ttagtatcta tttttatata gttgtaaaag aatatttcaa
     4861 catattaaat tattttatct tatatttttc tctttagttt cacacatcac caagtctaaa
     4921 ccttatatta tatattaata tttttgactt gtcaagttat ttatgttata atattaatca
     4981 ttagataatt aaagcattgt acctaagttg caatatctaa aattcaattt ggaggtataa
     5041 ctagcatatg tataaaattg gtgaaagtgt aatgtatcca aaagagggag cctgctctgt
     5101 aaatgatatt gtaacaaaga aaataaatca tgagatgcaa aaatactatg aattaagtgt
     5161 catttttaat agtaacctta aaatttcgat tccagttcta aatgcagata gaattggcat
     5221 acgtccagtt atggatggaa atgatgttga taattttatc caatctatta ataaaacaga
     5281 tggtgtatgg atttttgata gaaaagaaag acttaaactg taccaagata aatttcattc
     5341 aggagatgtt tttgaaattg taaaattaat caaaatgctt atgatacaag acagttcaaa
     5401 acaattgtgt agcacagata aggagttttt aaataaagct caaaaatttg ctttatcaga
     5461 attagctgct gctcaatgta aatcctatac aatggtatta gaggaaatga aaaaacatat
     5521 attaaattca aagaatacaa attaaaccag ttttttaaac tggttttatt ttttatacta
     5581 atcatccatg ctactttagc ttattttaaa ctgcctaatc taatattaat aaagttatct
     5641 caattagata gatgtatttt attcaaataa aaaaaactaa gagtaaatca tattactgat
     5701 ttactcttag ctaataaaat ttaatcttct tcaagttctt ttttctcttg taataataca
     5761 cttaattcat ttgcttctaa aacttgtgcc tctgcaatat caagtaactc ttgttgccat
     5821 tccacacatt tatctttgta atcaaaaggt agcgttctgt caactatgta cttatcaata
     5881 cagtcctccg cacttttaat tatttctttt ctttcatcaa taaatttttc taattctact
     5941 aaggcttctt cataagcttt tctactcata taaattcccc ctttgtacaa ttattctaca
     6001 ttaaaatgat ttttcctctt ttttgtataa aattttattt gtatataact tttccatcaa
     6061 tatcttttat agtttgacat ccagttaata tcatagaact acttagctct gattgaagtt
     6121 tatttacata agtttctaca ccatcagttg caccaccaaa agaagcagtc acaaaaggtc
     6181 ttcctattaa tactgcatct gcacctaaac ctatcatttt tagtacgtct aaaccagttc
     6241 tcactccacc atctgcaagt attgtaactt tacctttaac agcatcagca atttttggta
     6301 aaacttcaca tgctcctggt gtacagtcaa gcactcttcc tccatgattt gatacaacta
     6361 ttgcatccac acctgcttct actgccatta aagcatcttc aacagtcatt atacctttca
     6421 atataaatgg tagtttagta gactttacta actcctttat ttgtttaaca tttttaggaa
     6481 gtactggttt tccatgtaat gataaagtta ctagaccaca ggcatctata tcaactccaa
     6541 ctgcaaatgc accagcttct tcagctaatc ttatcttttt tataatattt tcattatccc
     6601 aaggtttaat aaatacaatt ccagctccat tatacttttt gactacatct aaattttcca
     6661 ttaaaaaagc atctactgcc gtatcaccaa ccattgcata aataccacta ttagcacatc
     6721 ctgcaactac tggttctatg taatctcttt cattaatttt tccacccata tttaaagtag
     6781 ttcctgttac tggagctgca aatataggtg cactcatttt ctttccaaac atctctatag
     6841 atgtatcagg atttgataca tcatgtatta ctctcatatt tacttttact ttttctaaac
     6901 tcttgctatt ttctataaaa gaagaaccac ttcctttacc tcccatgcca ggcacttcac
     6961 ctgcacaagc aaccccatta caaaccttac aaactttaca acttccattt aaattttctc
     7021 tagcactttt taataattca ttatattcca tctttaatcc cccattaact atagtaattt
     7081 atattatata cattatatca tattatattt acagtatatt tttcaaaaaa ctttttctgt
     7141 ggataggagt tatgccatat ttttcaatag cttcatagtg ttctttagtt ccatatcctt
     7201 tgtgagattt aaacccatat tctgggtata ctctatcata ttggtacatt atactatccc
     7261 tagtaacttt agcaagtata cttgctgctg ctattgatat agattttgaa tctcctttca
     7321 caattggatt ttgagatatg tcaatacctg gtattgttgc tgcatcaact aataaataat
     7381 ccggtgcttt ttttaaacaa tttatagcct ttttcattgc catatatgta gcatttaata
     7441 tattaaattc atctatttct tcattgttta ctatacctat tccataatct agtgcttctt
     7501 cttttattac ttcaaaaagt tcatctcttt ttgcctcact cagtttctta gagtcattta
     7561 caccttctat tttggtatct tttttaaata ctacaacaga agctacaaca ggtccagcaa
     7621 gtggtcctct tcccgcctca tcaattcctc caatatataa ataaccttta tcatagcctt
     7681 cgttctcaaa tatatttata gtttccaatc tttcttcttc ttttctaata ttatccagct
     7741 tttttgctag ttttatagct agaccttgta cagattttct ttcatcaact cttaacagct
     7801 ctatatattc catatatttt tctacttcta aagtctctat tatttcttta atctccctca
     7861 cacttttatc ctgcatacca ttccctcatc tttcgttttt aaaaatttaa tttttaaata
     7921 tattaaaatt ttttaattag agtttaattg catccactat agccacattt taaacatata
     7981 ctacatccac ctgtatgtgc aattccttca cttccacact caggacacac aaatttttca
     8041 tcttcttcaa aatttttatt tattatttct ttggcttttt catctttatt atctttttct
     8101 tttttattat ttttataata ttctttttta ctattttctt ttttatcttc tttattattt
     8161 tcttcctttt tttcatttat taaaattcca ctccttttac atccatctct aaatattgtt
     8221 actcctttaa gaccagcctc ccatgcctta atatatatat tgaaaacatc ttcaactgta
     8281 gtttcaaaag gtatatttat tgtagatgat atagaagcat caatatactt ttgccatact
     8341 ttttgcatgt ttattctttc ttcatatcct atattcatag cagtaacaaa aaaatctggt
     8401 aaacattctt catctgtaat acctttcttg tccatatact ctttaacaat tggagtatat
     8461 actttataat acacatcctc atcatgcaag ctttcagttt ttcttatata tgaaagatta
     8521 aatataggtt ctattccacc actaatacct atcattgtag atatagaacc tgtaggaggt
     8581 atggttaaaa gttgtgaatt tctaagccca tactttttaa ccatttcctt agtgtcttca
     8641 tttagatttt ctataaaaaa cttagattta gaaatatttt catatttata ctcactaaat
     8701 gttccatatt ctttagcaat tagtgctgat tgcttcacag cttcatttaa catagtctta
     8761 ccaattaaat cacatagttc taaagattca tcagaaccat atcttattcc catttttata
     8821 agcatatcag ctatacccat tacacctaaa cctatctgtc tatacttatg tacactatct
     8881 ctttgttctt gtaatggatg caagttcaat ccctcatcta agacatcatt taaagctact
     8941 acagcttctc taacgcaaga ttttaattta ttaatatcaa aagtagcatg ttcaccaaat
     9001 ggttgtatta taaactctga caagtttatt gagccaagta gacaacttcc tccacttgga
     9061 agtggttctt ctgcacaagg atttactcct gaaaagcaaa agttcttatc ttcactcata
     9121 aaattatatg tttttatttt atcccaaaac aatatacctg gttctgcata atcccagtta
     9181 tttttcacaa atttattaaa taaatcataa gcatttacta tcttaactat tttttctcca
     9241 gtagtttcaa cttcaaaagt acaattatat aacttttttt ctcttacagc ttgcataaat
     9301 tcatctgtta ctcttacaga aatatttgct ttagtaacct tctccaaatc tgtttttata
     9361 tctataaagt cttctatctc tggatgattt acatccatag aaatcataag agctcctctt
     9421 ctccctcttt gaccaattaa gccagttgtc atactgtaaa gttccataaa agagactgct
     9481 ccagtcgtat gttttgcagc attgttaact ttcgctcctt ttggtcttag ctttgaaata
     9541 tcaattccaa ctcctccacc ataactaaaa gttctagcaa gtttttttgc agtatcaaat
     9601 atatcttcta tgctatcttt tggtggttct attacataac aattagaata tgttactttt
     9661 tttccttctt tctgtaatcc tctatttgct aaaattcttc cagcaaatag aaatcttttt
     9721 tgtcttatta gttttgatat tcttgaacta ttatttgaaa ttctctttat ccattcatca
     9781 aaactctcac cattatgtct atacttgttc ttccatattg atttttgtaa ttcatcaaac
     9841 tcccaagctt tagtccttat ttcagagcgt ctttctctat ataatatgta gtgttttgct
     9901 atatcttttc tatttgattc cataagtagt acttcaacta tatcttgtat ttcttctacg
     9961 gataagcatt tttccataga attatagtca ttagctattt ttcttgatat atcatatgcc
    10021 aactctctat ctactccacc ttcactattt atactagctt tatagacagc atcttcaatc
    10081 ttacttttac taaaaagttc ttttgtacca tctcttttta ttatgtattt catttttaaa
    10141 cctccaataa attagtatta aattaataca cacattaact ataactctaa acaaactttt
    10201 tatatatttg tatattttca tattaattat ctaacataat
//
LOCUS       DAMJVG010000112         9876 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.117, whole genome shotgun sequence.
ACCESSION   DAMJVG010000112 DAMJVG010000000
VERSION     DAMJVG010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9876)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9876)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9876
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.117"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            350..1366
                     /gene="gap"
                     /locus_tag="PC512_003356"
     CDS             350..1366
                     /gene="gap"
                     /locus_tag="PC512_003356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HDF2443075.1"
                     /translation="MKIKVGMNGFGRIGRAVLRIAQEELGDNIEIVAINARATTESLA
                     HLFTYDSCYGTFRGEVEAKDEDTLVVNSKEIKILRYNDPEELPWKELGVDIVIESTGL
                     FTQREKAEKHIKAGAKKVIITAPGKNEDITIVIGVNEKEYDNEKHNIISNASCTTNCL
                     APFAKVLDEKFGIVKGLMTTVHSYTNDQRILDKSHKDLRRARAAAESIIPTTTGAAKA
                     VSRVLPQLEGKLNGFSLRVPTPTVSLVDLVCELKENVTSEQVNSVLKDAAEGELKGVL
                     GYCDKPLVSIDYKGDSRSSIIDALSTMVIEDNMVKVVSWYDNEWGYSSRTVDLVKYVA
                     EKLK"
     gene            1761..2930
                     /locus_tag="PC512_003357"
     CDS             1761..2930
                     /locus_tag="PC512_003357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443076.1"
                     /translation="MEKLTDRRQVKAVSMETFIFLILLVVGFGYVGSIMGAGMMFKVI
                     MSTAHALLLETVFLIMAMAVLAGALSALLSEFGVIALINKIFAVFMKPLYGLPGASIA
                     GAITTYLSDNPAIIPFAKDKTFTQYFKQYQVPALCNLGTAFGMGLILTTFMISQGTEY
                     VLPALIGNLGAIIGSVISVRIMLTFTKKFYKYNPEEDKATGTLEKKDEFREIREGNVF
                     QRALDAILEGGKMGVDMGMAIIPGVLVVCTLVMLLTFGPSTDPVTGQEVYTGAAYEGI
                     KLLPVIGDKLGFILEPLFGFTSPEAIAFPITSLGAVGAAMSLVPEFIKSGAITPNDIA
                     VFTAMGMCWSGYLSTHIGMMDALNARQLAGKAILSHTIGGLCAGAAAHFIFTLVG"
     gene            3310..7563
                     /locus_tag="PC512_003358"
     CDS             3310..7563
                     /locus_tag="PC512_003358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacyl-CoA dehydratase"
                     /protein_id="HDF2443077.1"
                     /translation="MDELFHIGIDVGSTTVKVVVLNNSNNIVHKEYRRHYSDVKKSVK
                     EVLNGIYEKLGDINTTIIITGSGGIGISKKLGVKFVQEVISSTKSIEYFHPETDVVIE
                     LGGEDAKITYLSGGIDQRMNGICAGGTGAFIDQMASLLKTDASGLNELAKGYNVIYPI
                     ASRCGVFAKTDIQPLINDGANQTDIAMSIFNAVVVQTVSVLSCGRKIEGNVAFLGGPL
                     YFLSELREAFKRVLDLKDENIIFPENAQLYIAIGAGLLSVDEDNIQLKSLIEKLDSIK
                     NIEDGEVNLLEPLFKDKNEYEEFSRRHEKEKINYVDINSIKSNCYLGIDAGSTTTKAA
                     LIDEDGRLVYSYYNSNEGNPLKTTIKVINEVYDILPKNIKILSSTVTGYGEGLIKKAL
                     KIDNGEIETIAHYKAAKFFNKDVDFILDIGGQDMKCLKIKDGVIDNIILNEACSSGCG
                     SFLETFASSLSMTIEEFAHEGIYSQNPVDLGSRCTVFMNSRVKQAQKEGASVGDISAG
                     LSYSVIKNALFKVIKIRDLNEIGNNIVVQGGTFYNDLVLRSFEKLIGKNVIRPNISGI
                     MGAFGSALIAKEKYESGYKTSLLSKEELNNIKLEASVTRCKGCSNHCLLTINKFSDNE
                     IFISGNRCEKGEAIYGDKKIGLEKKKPINLFKYKYNRIFRYKPLEKEEAKNGEIGIPR
                     VLNMYEDYPFWFTFFNAMGFRVVLSDRSSKQLYETGITSIASETVCYPGKLVHGHIEN
                     LIAKGIKNIFYPSVTNENKEDSNADNYYNCPVVISYSEVIKNNVENIRNKNINYINPF
                     ISLNDKEKLKKRLYDELSRHFSDIKITKEEVNHAVDKATDEQNLFKMEIQAAGERALK
                     EIKERNMKGIVLCGRPYHIDPEINHGMPELINSLDMAVLTEDSICHLANVQRPLRVVD
                     QWVYHSRLYKAASFVRDKNYLELVQLNSFGCGLDAVTTDQVQEILNEKSKIYTIIKID
                     EGNNLGAAKIRMRSLKAAMFERESKNIDVKNIKVNRIQYAKNNQITNKHTILAPQMSP
                     IHFQFLEKAVNLSGYNIEILKDTDSSVIEEGLRYVNNDACYPAIIVVGQLITALKSGK
                     YDLNNTSVTITQTGGGCRATNYIGFLRKAIYDAGFKDIPVIALSVNGIEDSGIMDNIS
                     LKLINRLFMSVVYGDLLMKVLYRVRPYEKVTGSANALYEKWVDICKSSLVKAKISVFT
                     RNIKDIVKEFDNLEILDIKKPKVGLVGEILVKFHPIANNNLVDILEREGAEAVVPDLT
                     NFFLSCAFNTIYKHTHLEGSRKSRMIGEAFIYITGIYQRVYKKALDKSERFYAPANIK
                     NVAKSTEPVVSLGNQTGEGWLLTGEMVELLNEGVENIICMQPFGCLPNHIIGKGSIKE
                     LKRLYKNANIIPIDYDPSASEVNQLNRIKLMLSKAFKNI"
     gene            7712..8206
                     /locus_tag="PC512_003359"
     CDS             7712..8206
                     /locus_tag="PC512_003359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HDF2443078.1"
                     /translation="MSLVYDVYKSKLGNLYILSEDGFIVSIYIGDEKFNNLKNECIKK
                     GIDIKRSKEDLKEAISQIDDYFNGKRKVFNLNIRIEGTEFQKSVYREMLKIPYGETLC
                     YSDIARNINNPKSVRAIGQASKSNKIPIIIPCHRVVGKKDIGGYMGNHSDLKEILLNL
                     ERQS"
     gene            8322..8699
                     /locus_tag="PC512_003360"
     CDS             8322..8699
                     /locus_tag="PC512_003360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monooxygenase"
                     /protein_id="HDF2443079.1"
                     /translation="MCDKVIASKYHEKGFNCAESVIKAYNEEFNTDIPVCLGSGLGSG
                     CGVASLCGAVNASNIIIGYVKGRNHEDESTKAKVYAKDLTTTVRKEYGSELCIDLKKD
                     LVACREIMDFAYDSLKETLKKEL"
     gene            8905..9345
                     /locus_tag="PC512_003361"
     CDS             8905..9345
                     /locus_tag="PC512_003361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SufBD protein"
                     /protein_id="HDF2443080.1"
                     /translation="MKNLNLLINKLYSKNHNEAYKTFLFLENESLKSNITYCFFDSFL
                     EMIDNENSYIRTRGLLLISANAQWDIDNKIEINIDSILSHIVDKKPSVSRMFIKSIPN
                     ITKYKENLINRIKMELSNADISIYNNNMKPLVEKDINDTLSNIS"
BASE COUNT         4031 a          992 c         1733 g         3120 t
ORIGIN      
        1 aatcatatat tttttgaact aaataaaaat ttatttttat tattttaaat tagaggagat
       61 tcttgaagat atattatttt taaaaataag tatagtttaa aaattcaaaa aaaagatggc
      121 aaaatatgtc ccaagggaca ttgagtaaaa taaatgattt cagcttattt acactaaaaa
      181 gtacatacta aatgaggggt aaaataaaga aaaatgatat actaattgtc ttttgataat
      241 aaaaaaacat ggaatttgat tatttaatca agaaaaagta ttgaacaaat gatttattta
      301 gtgtacaata atcatgtaaa aacatagtaa tggagggaga catttcataa tgaaaattaa
      361 ggtaggaatg aacggatttg gaagaatagg aagagctgta ttaagaatag ctcaagaaga
      421 attaggagat aatatagaaa ttgtagccat aaatgcaaga gcaacaacag aatctttggc
      481 acatttattt acatatgatt catgctatgg aacttttaga ggtgaagtag aggcaaagga
      541 tgaagacact ctagtagtaa actctaaaga gataaaaata ttaagatata atgacccaga
      601 agaattacct tggaaagaat tgggggttga tatagtaata gaatcaacag gattatttac
      661 acaaagagaa aaggcagaaa aacatattaa agcaggagca aaaaaagtaa ttataacagc
      721 tccaggaaaa aatgaagata taactatagt tatcggagtt aatgagaaag aatatgataa
      781 tgaaaagcac aatataattt caaatgcatc ttgtactaca aattgtctag ctccttttgc
      841 taaagtattg gacgaaaaat ttggtatagt aaaagggtta atgactacag tacattcata
      901 tactaacgat caaagaatat tagataaaag ccataaagat ttgagaagag caagagcagc
      961 ggctgaatct ataataccta ccactacagg agcagcaaaa gctgtgtcaa gagtactacc
     1021 acaattagaa ggaaaattaa atggtttttc acttagagta ccaacaccaa cagtttcact
     1081 tgttgattta gtgtgcgaac ttaaagaaaa cgttacatct gagcaagtta actctgtgtt
     1141 aaaagatgct gctgaaggag aattaaaagg tgttttagga tattgtgaca agccacttgt
     1201 ttctatagat tataaaggag attcaagatc atctattata gacgctctat ccacaatggt
     1261 tatagaagac aatatggtta aggtagtttc ttggtatgat aatgaatggg gatattcttc
     1321 aagaactgtt gacttagtaa aatatgtagc tgaaaaatta aaataatata tatttcttaa
     1381 agcaaatttt aaaaaaattt tttaaaaaaa ttatataaaa ctaaaaaaaa agattatgaa
     1441 aaatattgaa ggaaaaattt tttcataatc ttttttcttt catgcaaaaa gatacaagtt
     1501 acaacttata tttgcatatt aggtcgttag agaagtatat atatatttag taaggaatca
     1561 tactttttat aaaatgaaag ataagatgtc gaaaacttgc ataaatctga aaaattttta
     1621 ttattaaaat actgatttcc attttaaaaa tgataaaaaa atgacaaata aagttgcaaa
     1681 tagtaatact tataagtata attaaaaaag agaaaaggtt ttgttaaact ttataacaaa
     1741 aaaagaaggg atgattcaaa atggagaagt taacagacag gagacaggtt aaggcagtaa
     1801 gcatggaaac cttcattttc ctaatattac tagtagttgg ttttgggtat gttggtagta
     1861 ttatgggagc aggaatgatg ttcaaagtaa taatgagtac agcacatgct ttactattgg
     1921 agacagtttt cttaattatg gctatggcag ttcttgcagg cgcattaagc gcactacttt
     1981 cagagtttgg agtaatagcg ttaattaata aaattttcgc tgtatttatg aagcctttat
     2041 atggactacc tggtgctagt atagcaggag ctataacaac ttatttatca gataatccag
     2101 ctattatacc ttttgctaaa gataaaacat tcacacagta ttttaaacaa taccaagttc
     2161 cagcattatg taacttagga acagcctttg gtatgggact tatcttaaca acatttatga
     2221 tttctcaagg tacagaatat gtacttccag cattaattgg taatttaggt gcaattatag
     2281 gtagtgtcat aagtgttaga ataatgttga catttactaa gaagttttat aaatacaatc
     2341 cggaagaaga taaagcaaca ggaacattag agaaaaagga tgaatttaga gaaatcagag
     2401 aaggaaatgt atttcaaaga gctttagatg caattcttga aggtggtaaa atgggggtag
     2461 atatgggaat ggctataatt cctggagtcc tagtagtatg tacattggtg atgttattaa
     2521 cttttggacc atctacagat cctgttacag gtcaagaagt ttatacagga gctgcatatg
     2581 aaggaataaa attacttcca gttattggag ataaacttgg atttatatta gaaccattat
     2641 ttggatttac atcaccagag gcaatagcat tccctataac ttcattggga gctgttggcg
     2701 cagcaatgtc tctagttcca gagtttataa agtcaggagc tataactcct aatgatatag
     2761 cagtatttac agctatgggt atgtgttgga gtggatattt aagtacacat attggtatga
     2821 tggatgcatt aaatgctaga cagttggcag gtaaagctat tctttctcat acaataggtg
     2881 gtttatgtgc aggagcagct gctcacttta tatttacact cgtaggataa atgtaatcag
     2941 ctaagataaa aaataatata caaaaaatgg ttgttgatat gtaataagaa tttacatatc
     3001 aacaaccatt tttttctgac taaagataat ttataataca taaacattaa gtggatatta
     3061 gagttaagtt atatttatgt aaaaagtaac aaaaatctgt agaaatttat gacaaaattt
     3121 agtacactaa ctatatgttc ttatttaaaa tttaaggtta gaattaggaa ttacctagta
     3181 gagtaagctt tgattaataa aagaatcata aaataaaaat attagtcata aagattataa
     3241 ataacttact taaaataaag ccatagaact tacaaaaatt aaaaaagcat ataaatatgg
     3301 aggggtacaa tggatgaatt atttcatata ggaattgatg taggttctac aacggtgaag
     3361 gttgtggtac ttaataatag taataatata gttcataaag aatatagaag acattattct
     3421 gatgtaaaaa aatcagttaa agaagtacta aatggtatat atgaaaaatt gggagatata
     3481 aatactacca ttataataac tggttcaggt ggaattggaa tatcaaaaaa attaggtgta
     3541 aaatttgttc aggaagttat atctagtaca aaatcaatag agtattttca tcctgaaact
     3601 gatgttgtca tagaacttgg gggtgaagat gcaaagataa catatctaag tggaggaata
     3661 gaccaaagaa tgaatggaat atgtgcaggt ggcactggag cattcataga ccagatggca
     3721 tcacttttaa agacagatgc cagtggatta aatgaacttg ctaaagggta taatgttata
     3781 tatcccatag cttcaagatg tggtgttttt gctaaaacag atattcaacc tcttataaat
     3841 gatggagcca atcagactga tatagcaatg agtattttca atgcagttgt cgtacaaact
     3901 gtgagtgtcc tttcttgtgg aagaaaaata gaaggaaatg ttgcgttttt gggtggtcca
     3961 ttgtactttt tatctgaact tagagaagca tttaaaagag tattagattt aaaagatgaa
     4021 aacataatct tcccagaaaa tgcacaactt tatattgcta ttggagcagg attattatca
     4081 gtagatgaag ataatataca actaaaatct ctaatagaaa aattggatag tataaagaat
     4141 attgaagatg gagaagtaaa tttattagaa cctttattta aagataaaaa tgagtatgaa
     4201 gaattttcaa gaagacatga aaaagaaaaa ataaattatg tggacataaa ttcaataaaa
     4261 agcaattgtt atttaggaat tgatgcaggc tcaactacaa ctaaagcagc acttattgat
     4321 gaggatggaa gacttgtata ttcttattat aatagcaatg aaggaaatcc attaaaaaca
     4381 accattaaag ttataaatga agtatatgat atattaccaa aaaatattaa aatattgagt
     4441 tcaactgtaa ctggatatgg agaaggtctt attaaaaaag ctcttaaaat cgataatgga
     4501 gagatagaga ctatagcaca ttacaaagct gctaaatttt tcaacaaaga tgtagatttt
     4561 atacttgata ttggtggtca agatatgaag tgcctaaaaa taaaagatgg agtaattgat
     4621 aatataatat taaatgaggc ttgttcatca ggttgtggct catttttaga gacatttgca
     4681 agttctttat ctatgacaat agaagaattt gcgcatgaag gtatttattc tcaaaatcct
     4741 gtagatttag gttcaagatg tactgtattt atgaattcta gagtaaaaca agctcaaaaa
     4801 gaaggtgcaa gtgttggaga tatatcagca gggctatctt attcagtaat aaaaaatgct
     4861 ttatttaaag taataaagat tagagattta aatgagattg gtaataatat tgttgtacaa
     4921 ggtggaacct tttataatga tttggtgctt agaagctttg aaaaactaat tggaaaaaat
     4981 gtaattagac ctaatatttc aggaattatg ggagcttttg gttcagcact tatagctaaa
     5041 gaaaaatatg aaagtggata caaaacatcc ttgttatcta aggaagagtt gaataatatc
     5101 aagctagaag caagtgtaac tagatgtaaa ggttgttcaa atcattgtct tcttacaata
     5161 aataaatttt ctgataatga aatttttatt tcaggtaata gatgtgagaa aggtgaagct
     5221 atttatggtg ataaaaaaat aggattagaa aagaaaaaac caataaattt atttaagtac
     5281 aaatacaata gaatttttag atacaaacca ttggaaaaag aagaagcaaa aaatggggaa
     5341 atagggatac caagagtatt aaatatgtat gaagattatc cattttggtt tacttttttc
     5401 aatgctatgg gctttagagt tgtactttca gataggtcat caaaacagtt atatgaaact
     5461 ggtataacta gtattgcatc tgaaacagtt tgttatccag gaaaattagt tcatggacat
     5521 atagaaaatt taattgcaaa aggtataaaa aatatatttt atccaagtgt aacaaatgaa
     5581 aataaagagg attcaaatgc agataattat tataattgtc ctgttgtaat atcatattct
     5641 gaagtaataa aaaacaatgt agagaatata agaaataaga acataaatta tataaatcca
     5701 tttataagtc taaatgacaa ggaaaaattg aagaaaagac tctatgatga attatcaaga
     5761 catttttctg atataaaaat aactaaagaa gaagttaatc atgcagttga taaagctact
     5821 gatgaacaga atttatttaa aatggagata caagcagcag gtgaaagagc acttaaagaa
     5881 ataaaagaaa gaaatatgaa ggggattgtg ttatgtggaa gaccatatca tatagaccca
     5941 gaaataaatc atggaatgcc agagcttata aattcattag atatggcagt gcttactgaa
     6001 gactctatat gtcatttagc caatgtacaa agaccactta gagttgtaga ccaatgggta
     6061 tatcattcaa gattgtataa agcagctagt tttgtaagag ataaaaacta tttggaactt
     6121 gttcaactta attcatttgg ctgtggatta gatgcagtaa ctacagacca ggttcaagaa
     6181 atacttaatg aaaaatcgaa gatatatact attataaaga ttgacgaagg caacaattta
     6241 ggagcagcta agataaggat gaggtcctta aaagcagcta tgtttgagag agaaagcaaa
     6301 aatatagatg taaaaaatat aaaggtaaac aggatacagt atgctaaaaa taatcagata
     6361 acgaacaaac atactatatt agcaccacaa atgtctccaa tacatttcca attccttgaa
     6421 aaagctgtta acttaagtgg ttataatata gaaattctaa aagatactga tagtagtgta
     6481 attgaagaag ggttaagata tgtaaataat gatgcatgtt atccagctat aatagttgta
     6541 ggtcagctaa taacagcatt aaaatctggc aaatatgatt taaataacac ttctgttact
     6601 ataactcaga ctggtggagg ttgtagagct acaaattata ttggattctt aagaaaggct
     6661 atatacgatg ctggatttaa agatattcct gtcattgcac ttagtgtaaa tggaatagaa
     6721 gatagtggta taatggataa tatatcacta aaattaatca atagactctt tatgtctgtt
     6781 gtttatggtg atttgctgat gaaagtacta tatagagtaa gaccatatga aaaagttact
     6841 ggaagtgcaa atgctctata tgaaaaatgg gttgatatat gcaaatcttc tcttgttaaa
     6901 gcaaaaattt ctgtatttac tagaaatata aaagatatag taaaagaatt tgataattta
     6961 gagatactag atatcaaaaa accaaaagta ggtttggttg gagaaatatt ggtgaaattc
     7021 catccaattg caaataataa tttagtagat atattagagc gagaaggtgc tgaagcagtc
     7081 gtgccagacc ttacaaattt cttcttaagt tgtgccttta atactatata caaacacact
     7141 catttagaag gaagtagaaa gagtagaatg ataggagaag catttatata cataactgga
     7201 atatatcaaa gagtatataa aaaagcactt gataagagtg agagatttta tgctccagcc
     7261 aatataaaaa atgttgctaa aagtacagaa ccagtagtgt cattaggtaa tcaaactgga
     7321 gaaggttggc ttttaacagg tgagatggtt gaattattaa atgaaggtgt agaaaacatt
     7381 atttgtatgc aaccttttgg atgtttacct aatcacataa ttggtaaggg ttctataaaa
     7441 gaattaaaga ggttgtataa aaatgcaaat ataataccta ttgattatga cccttctgca
     7501 agtgaggtaa atcaacttaa caggataaaa cttatgcttt ctaaggcttt taaaaatata
     7561 taagatttat attttgatat gttaaaagtt aatgaattta aaaatatact ctatattaag
     7621 tatctataaa aaagagttat cctatttttt agggtaactc tttattagtt aaaaaattat
     7681 atgtatactg atattaaagg ggggaagtaa tatgagttta gtatatgatg tttataaatc
     7741 aaaattagga aatttgtaca tattaagtga agatggtttt atagttagta tatacatagg
     7801 agatgaaaaa tttaataatt taaaaaatga atgtattaaa aaaggaattg atataaagag
     7861 aagtaaggaa gatttaaagg aagcaataag ccagatagat gattacttta atggaaaaag
     7921 aaaagtcttt aatttaaata ttcgtattga agggactgaa tttcaaaaat cagtttatag
     7981 ggaaatgtta aaaatacctt atggagaaac attgtgttat tcagatatag caagaaatat
     8041 aaacaatcca aaatcagtaa gagcaatagg acaagcaagt aaaagtaata aaattccaat
     8101 aataatacct tgtcatagag tagttggcaa aaaagatatt ggtggatata tggggaatca
     8161 ttctgatttg aaagagatac tattaaattt agaaagacag agttaactta gaaagaaatg
     8221 tttttattgt taatatttga tataataata gtaaaaagaa gtatttttta caaaaacaat
     8281 gaagaattta ttttaattta taaaaatgag ggggaatttt aatgtgtgat aaagttatag
     8341 catcaaaata tcatgagaag ggatttaatt gtgcagaatc agttataaaa gcatataatg
     8401 aggaatttaa tacagatata ccagtttgtt taggaagtgg actgggttca gggtgtgggg
     8461 ttgctagttt atgtggtgca gtaaatgcat caaatataat aattggatat gtaaaaggca
     8521 gaaaccacga agatgaaagt actaaagcta aagtatatgc taaagattta actacaacag
     8581 taagaaaaga gtatggttca gagttatgta tagacctaaa aaaagattta gttgcttgta
     8641 gagaaataat ggatttcgca tatgatagtc taaaggaaac tttaaaaaaa gaattataag
     8701 aaaataagct atcaagtata aattatttga tagcttattt ttatagtcga tactaaataa
     8761 atcaaatata ttttagaatt attatttgta aataaacagc aaataatttt aggattttta
     8821 tttaatatag tttttattta tatttatttt tgaatatgtt atactttgtt taaataaata
     8881 tttgtaatga gggagatgag aagattgaag aatctcaatt tacttattaa taaattatat
     8941 tcaaaaaatc ataatgaagc atataaaact tttttattct tagaaaatga aagtttaaaa
     9001 tcaaatatta catattgttt ttttgactca ttcctagaaa tgattgataa cgaaaactca
     9061 tatattcgaa caaggggatt gttattaatc tctgcaaatg ctcagtggga tattgataat
     9121 aaaattgaaa taaatataga tagtatacta agtcatatcg tagataaaaa accttctgta
     9181 tcaagaatgt ttattaaatc catacctaat attacaaagt ataaagaaaa tcttattaat
     9241 cgcataaaaa tggaattaag taatgcagat ataagtattt ataataataa tatgaaacca
     9301 ttagtagaaa aggatataaa cgatacatta tctaatatta gttaaatatt aatatagaaa
     9361 ttgaatatta tctagttaca attatttata actaagataa taaaacaaca atggtgctaa
     9421 tttatatgta taaattaatt atgaaaaatt tatataagta aaatatatta acataaaggt
     9481 aaaattttgt atactaaaag ggaatattta cagtttaatg gcagttttaa aataataaat
     9541 taaagctgtc atttttattt aaaaattttt agaaaaagta caatagtgtt aatgtgtgaa
     9601 ttagataagg tgtatataat agtttagatg atatgatata aaatatgttg taaattaaat
     9661 gttttctttg acaatatata cacaaggatg ataatatcta tatgaataaa agatagtgtg
     9721 taatttgata atatgtaatt ataacattat gatataatta caataaagta tgtaataatc
     9781 tgtagaaatt tcaagctagt tatctaagtt ttcggataac taaatctaaa cggaatacat
     9841 aatgtattaa ataaatgatg atactaaaat gatact
//
LOCUS       DAMJVG010000113         9498 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.118, whole genome shotgun sequence.
ACCESSION   DAMJVG010000113 DAMJVG010000000
VERSION     DAMJVG010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9498
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.118"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(150..803)
                     /locus_tag="PC512_003362"
     CDS             complement(150..803)
                     /locus_tag="PC512_003362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2443081.1"
                     /translation="MKVDPLTTQVYDYISKKIQNGEYEANQRITESEICKSIGVSRTP
                     AREALTRLAGENLLEKIPNKGFVVKEFQEKEKLDTYSVIGVLDALAGSSALQNLTESD
                     LVKMEELTEMMAVSIKYKNYNSYLKLSNEFHDIYITKSDNQVLVNLLNSLRYNFMSKS
                     YTSDNEDELYKMLTYSNNQHIEVVKSMRENDLENVERILREHWKTIPIAEMKKEKLL"
     gene            complement(1048..2913)
                     /locus_tag="PC512_003363"
     CDS             complement(1048..2913)
                     /locus_tag="PC512_003363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
                     /protein_id="HDF2443082.1"
                     /translation="MQSVIEYNSWDKNFKAPFGALKFDEELTICVKVNEGYNIKSISL
                     EINREEEMRTITLNEELDNDKLGKCFCGKIEKFDGTGVYFYYFKVDVEMDGQIKTLFY
                     GKNRDNGYSCEYNYSDINKYQITVYKDFKVPTWYKEGILYHIFVDRFNNGNRSGKVDN
                     PKKNSFIYGNWEDTPMYIKDSQGDVIRWDFHGGNLRGIINKLGYLKKLGVSILYLSPI
                     FEASSNHKYDTGDYKKIDPMFGDEDTFKELIDKAKEKGISIVLDGVFSHTGADSKYFN
                     MYGNYNSLGAYQSKESPYYSWYMFEEFPQKYKSWWDVKTLPNINELEHSYMDYIIYDN
                     DSVINKWVNMGIKGWRLDVADELPTKFIRELKKELKKADDDSILIGEVWEDASNKISY
                     GQRRSYLLGEELDSVMGYPFRNNMFSFLKGEINSYELCNRYMQIKENYPKESFRSNLN
                     LIGTHDVTRAKTELNDDVDLVKLAVAIQMTFEGVPYIYYGDEAGLCGGVDPDNRRTYP
                     WKNEDEDMLNFYRDVIKIRNKNKLLSSGNTEFIYTNNDSVFSFIRVNENNDRMLILVN
                     RSENVESISLCIESSFIEEIPIKYSLKNANSTIQIENNELKVDLDSKSFRIFRVN"
     gene            complement(2918..5338)
                     /locus_tag="PC512_003364"
     CDS             complement(2918..5338)
                     /locus_tag="PC512_003364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HDF2443083.1"
                     /translation="MVTISKKKFKQKFEVKMYSLYAQSIKEATDEQLLNVLCSLLKDE
                     IAKKWVATKLDKKKEVYYFSLEFLIGRQLKSNLLNLNIEEEVREGLSELGINLDDLIE
                     TEVDPALGNGGLGRLAACFLDSMASLNISGQGYGIRYKYGLFEQKFVNGYQVEVPDNW
                     LTEGRYAWETVRPNEATMVKFGGEVELIKEGSHLKVIHKNYLPVMAMPYDIPIIGYQN
                     QCINTLRLFKSEIPKRDFGELTSNALNYSGSYEEALKHKYYTEEISQVLYPDDSNYAG
                     KLLRLKQEYFFVSAGIQDIIRKYKKNKLNINNLFDKVAIHINDTHPTLCIPELMRILL
                     DEENLSWDEAWEITKKTVSYTNHTIMSEAMEKWPVSMMKELLPRIYMIIEEINRRYVE
                     ELNNKGYDQDRIKRMSIIDCDNINMANLCIVTSHSVNGVAKLHTHILETEVLKDFYQD
                     EPNKFNNKTNGIAHRRWLISSNPQLSNLITDLIGDSWKKDTLQLKNIEKFKNDSSVLQ
                     RLDDIKYNNKANLAKFIKDKYDLNVDPSSIFDVQVKRLHAYKRQLLNIFNVLHMYHEL
                     LDNPNLNLDPRTFIFGAKAAPGYYLAKCIIKFINSVASTINNDVRVKDKLKVVFLENY
                     GVSLAEIIIPAANVSEQISTTTKEASGTSNMKFMMNGAITLATLDGANVEICEQVGKE
                     NMFLFGLSAEQVLNYNKYGGYSSLDLYHSNMDIKRVVDDLINGFIPNLGEEGRSIYNS
                     LTTYNDEYFVLRDFENYGQAQADINRLYRDKEKWNKMSLVNIANSGFFSSDRTISEYA
                     KDIWFKRV"
     gene            complement(5352..6794)
                     /gene="glgA"
                     /locus_tag="PC512_003365"
     CDS             complement(5352..6794)
                     /gene="glgA"
                     /locus_tag="PC512_003365"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011053260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HDF2443084.1"
                     /translation="MKVFYVTAECWPFAKTGGLGDVSYALPKELKKEGVDVRVIMPKY
                     STIPSYLKDQLKEIAVFSVRVGWRNQYCGLLEMELDGVKFYFIDNEFYFRREDERKSI
                     YGYGDDAERYTFFTDAVLEAISRIDFYPDVIHINDWHTGMLPLILKERYATLEGYKNI
                     KTMYTIHNLQYQGVFDKHVLYDILDLPQKYFDNGDIEYYGSINFMKAGINFADKIITV
                     SPTYANEIQTSFYGEQLDGLLRKESGKLKGILNGIDYDLNDPAKDKDIFVHYDVDSID
                     KKVENKLRLQDILGLKKDSSIPLIGIVSRLVSQKGFDLIAYMMPELMREDLQIVVLGT
                     GEHQYQSMFNYYDSNFSDKVSARITFNASLAQQIYAASDMFLMPSLFEPCGIGQMLAM
                     RYGSLPIVRETGGLRDTVTPYNKFTGEGNGFSFKNYNAHEMFFCLKNAIKVFKDKEKW
                     IKLVENAMKTDNSWKKSAKEYIETYRDICD"
     gene            complement(6823..7953)
                     /gene="glgD"
                     /locus_tag="PC512_003366"
     CDS             complement(6823..7953)
                     /gene="glgD"
                     /locus_tag="PC512_003366"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HDF2443085.1"
                     /translation="MRNECLGIINLNKKGDPAINKLNYGRPIASTPIAGRYRIIDFAL
                     SNMINSGITKVGIFAKEKYRSLTDHIGSGKDWDLSRKKGGLSIFSPENTKYRNTYSHR
                     EGDIYTILANLDYIEKSEEEYILIAPSYMLCNLNYSQALEYHKKSHNDITIIYKNVNN
                     ANKDFAGNLTLNLDSNNRVINVGNNLGKFPRANICMETYIMKREDFVECIYNIVNKGN
                     YCYLEEFIIEEAENMKIGAYEYTGYLKCVNSVESYFEMSKDLLNLEVADELLYSERKI
                     FTKEKNESPTIYTDSAKVENSFIASGCLIEGTVKDSIIFRKVNVEKGTVIENSIVMQN
                     CVIKSNAKLYNAILDKNTSVSNGKELRGDEKYPLVVEKNTNI"
     gene            complement(7955..9115)
                     /locus_tag="PC512_003367"
     CDS             complement(7955..9115)
                     /locus_tag="PC512_003367"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HDF2443086.1"
                     /translation="MKKEMLAMILAGGQGSRLGVFTKRIAKPAVSFGGKYRIIDFVLS
                     NCSNSGIDTVGVLTQYRPLILNSHIGMGSHWDLDRINGGVYVLQPFMNEKEGNWYNGT
                     AHAIYQNMDFVDTYNPEYVLILSGDHIYKMDYSKMLKFHKEKGSKATIAVIEVPWDEA
                     SRFGIMNTNEDSSIYEFEEKPSEPKSNLASMGVYIFDWKMLRNYFKEAEKNPEINYDD
                     FGKNLIPKMLEDNVGMYAYPFKGYWRDVGTIQSLWDANMDIIKSPETLDLADPKWKIY
                     TNTMAMPPQYIGKNANVHRSMIADGCRILGEVGNSVLSHGVVVGKGSKVIDSVIMPNV
                     VIGENVTIEKAMIGECATINDNVQIKNVNNEINVVSEYENIEPRCVLIEGGL"
BASE COUNT         3011 a         1723 c          923 g         3841 t
ORIGIN      
        1 ttcattgatt tatatatgtt aatttaaata cattattcta tcgtagtgcc ttagagtttt
       61 tatttgtatt taaagttaaa tttattcttg tttttccttt aatatttaat agtaaaacaa
      121 caaaattata aaaaaaataa agagaaactt tataaaagct tctctttttt catctctgct
      181 ataggtatcg ttttccaatg ttctctcaaa attctttcaa cattttctaa atcattctcc
      241 ctcatagatt ttactacttc aatatgttga ttattgctgt atgtcaacat tttatataac
      301 tcatcttcat tatcactagt atatgacttt gacataaaat tatatcttaa agagttcaat
      361 agatttacta acacctgatt atctgattta gttatgtata tatcgtgaaa ttcattactt
      421 aattttaaat agctattgta atttttatac tttatagaga ccgccatcat ttctgttaat
      481 tcttccattt ttactaggtc tgattcagtt aaattttgta atgctgaaga accggctaac
      541 gcatccaata ctccaattac ggaataggtg tctaatttct ccttttcctg aaattctttt
      601 actacaaatc ccttattagg tattttttct agtaaatttt cacctgctaa cctagttaat
      661 gcttctctcg ctggtgttct actaactccg atagatttac aaatctcaga ttcagtaatt
      721 ctctgattag cttcatattc tccattttgg attttctttg atatatagtc atatacttga
      781 gttgtaagtg gatctacctt cataagacgt tcctccatat taagattata aaagttaaat
      841 ctccctacaa ctttggtaga gagttcagtt ttatcttact aatttatata atatcacaat
      901 tatgatattt tttatacttc tttgtaatat tttgaaatac taaaattctt atgataattt
      961 atacaaaaaa agtagaaaaa gttttgataa aacaaaactc tttccacatt cgccttattt
     1021 tctatttatt tttctaaaaa aagatattta atttactcta aaaattctaa atgatttaga
     1081 gtctaaatct actttcaact cattattttc aatttgtata gtactatttg catttttaag
     1141 actatacttt ataggtattt cctcaataaa actactctct atacataatg atatactttc
     1201 cacattttca cttctattta ctaaaattaa cattctatca ttattttcat taactctaat
     1261 aaaagaaaat acagaatcat tattagtata tataaattct gtatttccag aacttaaaag
     1321 tttattctta tttctaattt ttataacatc tctataaaaa ttaagcatat cttcgtcttc
     1381 atttttccat ggataagttc ttctattatc tggatcaaca cctccacaaa gacctgcttc
     1441 atctccataa tatatatatg gtactccttc aaatgtcatc tgtatagcta cagcaagctt
     1501 cactaaatct acatcatcat ttaattccgt tttagctctt gtaacatcat gtgttccaat
     1561 taaatttaaa ttagacctaa atgattcttt tggataattt tctttaatct gcatatatct
     1621 attacaaagt tcatatgaat taatttctcc ttttaagaaa gaaaacatgt tatttctaaa
     1681 aggataaccc ataacagaat ctaattcttc acctaataaa taacttcttc tctgaccata
     1741 gctaatctta tttgatgcat cttcccatac ttcacctata agaattgagt catcatctgc
     1801 cttttttaat tcctttttta actctcttat aaacttagtt ggtaattcgt ctgcaacatc
     1861 tagtctccag cccttaatac ccatatttac ccatttattt ataacgctat cattgtcata
     1921 tattatataa tccatatagc tatgttctaa ttcatttata tttggcaatg tcttaacatc
     1981 ccaccaactt ttatattttt gaggaaattc ttcaaacata taccatgaat aatatggaga
     2041 ttctttagat tgatatgctc ctaaactatt atagtttcca tacatattaa aatatttact
     2101 atctgctcca gtatgactaa aaactccatc taatactatt gatatacctt tttcttttgc
     2161 tttatcaata agttctttaa atgtatcttc atctccaaac attgggtcaa tttttttata
     2221 gtcacctgta tcatacttat gattactaga ggcttcaaat atagggctta gatatagtat
     2281 acttacacct aattttttta aatatccaag tttattgatt atccctctta aatttccacc
     2341 atggaaatcc catcttataa catccccttg actatccttt atgtacatag gtgtatcttc
     2401 ccaatttcca tatatgaaac tatttttttt aggattatca accttaccac tacgatttcc
     2461 attattgaat ctatctacaa atatatgata aagtattcct tctttgtacc atgttggtac
     2521 tttaaaatct ttataaacag tgatttgata tttattaata tcactataat tatattcaca
     2581 agaatatcca ttatctctgt tttttccata aaataaagtc tttatttgac catccatttc
     2641 aacatcaact ttaaagtaat aaaaataaac acctgtacca tcaaactttt caatcttacc
     2701 acaaaagcac tttccaagtt tatcattatc taattcttca tttaaagtta ttgttctcat
     2761 ttcttcttct ctatttattt ctagggaaat agacttgata ttgtatccct catttacttt
     2821 aacacaaatg gtcaattcct catcaaattt taaagctcca aacggagcct taaaattttt
     2881 atcccaagag ttatattcta ttacactttg catttaatca caccctttta aaccaaatgt
     2941 cttttgcata ctcagaaatt gttctatcag aagaaaaaaa tccagagtta gctatattaa
     3001 ctaaagacat tttattccat ttttctttat ctctatataa cctgtttata tctgcttgag
     3061 cttgaccata attttcaaaa tctctcaata caaaatactc atcattgtaa gtagtgagtg
     3121 aattataaat acttcttcct tcttcgccaa gattaggaat aaatccattt attaaatcat
     3181 ctactaccct ttttatatcc atattagaat gatataggtc aagtgaagaa tatccaccat
     3241 atttattata atttagtact tgttctgcac taagtccaaa taaaaacata ttttctttac
     3301 caacctgttc acatatctct acatttgcac cgtcaagtgt agccaaagtt atagcaccat
     3361 tcatcataaa cttcatatta cttgttccag atgcttcctt agttgtagtt gaaatttgct
     3421 cactaacatt tgctgctggt attattattt ctgctaatga tactccataa ttctctaaaa
     3481 atactacttt taacttgtcc tttactctaa catcattatt tatagtactt gcaacagaat
     3541 ttataaattt aattatacat ttagccaaat aatatcctgg tgctgctttt gcgccaaata
     3601 taaaagttct tgggtcaaga ttcaaattag gattatcaag taattcatga tacatatgaa
     3661 gtacattaaa tatattcagt aactgtcttt tatacgcatg caatctctta acttgaacat
     3721 caaatatcga acttgggtct acatttaaat cgtatttatc ttttataaac tttgctagat
     3781 ttgctttatt attgtatttt atatcatcaa gtctttgtaa aacagaggaa tcatttttaa
     3841 atttttcaat attttttaat tgtaatgtat ctttcttcca tgaatcacca attaaatctg
     3901 taattaaatt gctaagttga ggatttgaac ttataagcca tcgcctatgt gcaattccat
     3961 tagtcttatt attaaattta tttggttcat cttgatagaa atcttttaat acctctgttt
     4021 caagaatatg agtatgaagc ttagcaactc catttacact atgacttgtg acaatacata
     4081 agtttgccat attgatattg tcacagtcta ttatactcat tctttttatt ctatcttggt
     4141 catatccttt attatttaat tcctctacat atcttctatt tatttcttct attatcatat
     4201 aaattcttgg taatagctct ttcatcatac ttacaggcca tttttccatt gcttctgaca
     4261 ttatagtatg attagtatag gacactgttt ttttagttat ttcccatgct tcatcccaag
     4321 ataaattttc ttcatcaagc aaaattctca taagttctgg tatgcataag gtaggatgtg
     4381 tatcatttat atgaattgct accttatcga ataaattatt aatatttaat ttgttctttt
     4441 tatattttct tattatatct tgtatccctg cacttacaaa aaagtattct tgtttcaacc
     4501 tcaacaactt acctgcatag tttgaatcat caggatataa tacctgtgat atttcctcag
     4561 tataatactt atgttttaaa gcctcttcat agctaccaga ataatttaga gcatttgagg
     4621 taagttcacc aaaatctctc tttggtattt cactcttaaa caatcttaaa gtatttatac
     4681 attggttttg gtatccgatt attggtatat cataaggcat tgccattaca ggaaggtagt
     4741 ttttatgaat tacttttaaa tgactacctt ccttgattaa ttctacctca ccaccaaact
     4801 tcaccattgt tgcttcattt ggtcttacag tttcccatgc atatcgtcct tctgtaagcc
     4861 agttatcagg cacttctacc tgataaccat ttacaaattt ttgttcaaac agaccatatt
     4921 tataccttat tccatatcct tgaccactta tgttcaaaga tgccatagaa tctaaaaagc
     4981 aagctgctaa tctaccaagt ccaccatttc ctaaggctgg gtctacttca gtttcaatta
     5041 aatcatccaa gttgattcct aattcagata aaccttctct aacttcttct tcaatattta
     5101 aatttaataa attagatttt aactgtctcc ctattaaaaa ttctaaacta aaataataaa
     5161 cttctttttt cttatctaac tttgtagcaa cccatttttt tgctatctca tctttcaata
     5221 gactacataa tacatttaac aattgttcat cagtagcttc cttgatagat tgtgcatata
     5281 agctatacat ttttacttca aatttttgct tgaatttctt tttgcttatt gttaccaaaa
     5341 aaaccactcc tttaatcaca tatgtctcta tatgtttcta tatactcctt agctgatttt
     5401 ttccaactat tatctgtttt cattgcattt tcaactaatt taatccattt ttctttgtcc
     5461 ttaaatactt tgattgcatt tttcaaacag aaaaacatct catgagcatt gtaattttta
     5521 aaactaaatc cattgccttc tccagtaaat ttattataag gtgttactgt atctctaagc
     5581 cctccagtct ctctaactat tggtaaagaa ccatatctca tagctaacat ttgacctata
     5641 ccacaaggct caaataatga tggcattaag aacatatcac ttgcagcata tatctgttga
     5701 gccaatgatg cattaaaagt aattctagct gatactttat ctgaaaaatt agaatcgtaa
     5761 tagttgaaca ttgattgata ttgatgttct ccagttccta aaacgacaat ctgtaaatct
     5821 tctctcataa gttctggcat catgtatgct attaaatcaa atcctttttg agaaactaat
     5881 ctcgaaacta tacctatcaa cggaatagat gaatcttttt taagtcccaa tatatcttgt
     5941 aatctcaatt tattttctac ttttttgtca attgagtcta catcataatg aacaaatata
     6001 tctttatctt ttgcagggtc atttaaatca taatctatac catttaatat accttttaat
     6061 tttcctgact cttttctaag taatccatct aattgttcac cataaaaaga tgtttgtatt
     6121 tcatttgcat aagtaggact aacagttata attttatctg caaaatttat accagctttc
     6181 ataaaattta ttgagccata atactctata tctccattat caaagtattt ttgtggtaag
     6241 tccaatatat catataaaac atgcttatca aatacacctt gatattggag attatgtata
     6301 gtatacatag tttttatatt tttatacccc tcaagggttg catatctttc ttttagaatt
     6361 aatggtaaca tccctgtatg ccaatcattt atatgtatta catctggata aaaatcaatt
     6421 ctacttatag cttctaaaac tgcatctgta aagaaagtat atctttctgc atcatctcca
     6481 tatccataga tactctttct ttcatcttct cttctaaaat aaaattcatt atctataaag
     6541 taaaatttta caccatctaa ttccatttct aaaagaccac agtattgatt tctccatcca
     6601 acacgtacac taaacacagc tatttctttt agttgatctt ttaaataact tggtatagtt
     6661 gaatatttgg gcattattac ccttacatct acaccttctt tttttaattc tttaggcaat
     6721 gcataagaaa catctcctaa tcctccagtt tttgcaaagg gccaacactc tgctgttaca
     6781 taaaaaacct tcattagtca ttcccccttc taaaaaattt atttatatat ttgtattctt
     6841 ttccactaca agaggatatt tttcatctcc tcttaattct ttcccatttg atacactcgt
     6901 atttttatct aatattgcat tatatagttt tgcatttgac tttattacac aattttgcat
     6961 tactattgag ttctctataa ctgttccttt ttcaacattt acctttctaa atatgatact
     7021 atcttttaca gtaccttcta ttaaacaacc agatgctata aagctatttt ctactttagc
     7081 actatctgta taaattgtag gtgattcatt cttttctttt gtaaatatct ttctttcaga
     7141 atataataat tcatctgcaa cttctaaatt taataaatct ttgctcattt caaaatatga
     7201 ttcaacagaa tttacacatt ttagatatcc tgtatattca taggctccta ttttcatatt
     7261 ttctgcttct tcaataataa attcttctaa ataacaataa ttgcctttat ttacaatgtt
     7321 atatatacat tcaacaaaat cttcacgctt cataatatat gtctccatac atatgtttgc
     7381 tctagggaac ttacctaaat tatttcctac atttattacc ctattgttac tatctaaatt
     7441 tagagttaag ttaccagcaa aatctttatt tgcattattt acatttttat atattatagt
     7501 tatatcatta tgagattttt tatggtattc caatgcttga gaataattta aattgcatag
     7561 catatagctt ggagctatta aaatatattc ttcttcactc ttttctatat aatctagatt
     7621 agctaagata gtatatatat caccttctct atgtgagtaa gtatttctat acttagtgtt
     7681 ttctggacta aaaattgata ggccaccttt ttttctactt aaatcccaat ctttaccact
     7741 acctatatgg tctgttaatg atctgtattt ttcttttgcg aatattccaa ctttagtgat
     7801 tcctgaattt atcatattag ataaagcaaa gtctattatt ctatatcttc cagctattgg
     7861 tgtagatgct attggtcttc catagttaag tttgtttatt gctgggtctc cttttttgtt
     7921 taaatttatt atccctaaac attcatttct catcttaaag acctccttct attaatacgc
     7981 atctaggttc gatattttca tactcagaaa ctacatttat ttcattattt acattcttta
     8041 tctgaacatt atcatttata gttgcacact cacctatcat agctttttct atagttacat
     8101 tttcacctat tacaacattt ggcattatta ctgaatcaat tactttactt cctttaccaa
     8161 caacaactcc atgtgataat acagagttac ctacttcacc taaaattcta caaccatcag
     8221 ctatcattga tctatgaaca tttgcatttt tacctatata ttgtggaggc attgccatag
     8281 tatttgtata tatcttccac ttagggtctg ctaaatcaag tgtttctgga gattttatta
     8341 tatccatatt agcatcccat agactttgta tagttcctac atctctccag tatcctttaa
     8401 atggataagc atacattcca acattatctt ctaacatttt aggtattaaa ttttttccaa
     8461 aatcatcata atttatttct ggattttttt ctgcttcctt aaaataattt ctcaacattt
     8521 tccaatcaaa tatgtatact cccatagatg ccaaattgct cttaggttca cttggttttt
     8581 cttcaaattc atagatactt gaatcttcat ttgtattcat tatcccaaat cttgaagctt
     8641 catcccaagg aacttcaatc actgctattg tagctttaga gcctttttcc ttatgaaatt
     8701 ttaacatttt gctataatcc atcttgtata tatggtcacc agataatatc aatacatatt
     8761 ctggattata ggtatctaca aagtccatat tttgatatat cgcatgtgct gtaccattat
     8821 accaatttcc ttctttttca ttcataaatg gttgtaaaac atagacacca ccatttattc
     8881 tgtccaaatc ccaatgactt cccatgccta tatgtgaatt taatatcaac ggtctatatt
     8941 gagttaaaac acctacagta tcaataccag agtttgaaca attgcttaac acaaaatcta
     9001 taattctata cttacctcca aatgatacag ctggtttggc aattcttttt gtaaaaacac
     9061 ctaatcttga accttgccct cctgccaaaa tcatagctaa catctctttt ttcatttaat
     9121 gacactcccc tcatctagta attaatattt ataattgcat ttttactttt ataaacttta
     9181 tcagtcaata aatgtcgtgt ataaatgttg cttaaataat accttaataa aaataaaata
     9241 atatcaacta tacaattgat ataatgtata ccccataatg gacttaccga cgtatacatt
     9301 attttccata agcactatag tatttattaa tattcaatta ttggttaaaa aataatacaa
     9361 attttatttt ataaatataa aaacattttt tataaatcct ttgtgtcata tgaacatgct
     9421 tattttttaa tttgttaaat tcgtaatagc aaaatataat ctaatatttg ttaaataatt
     9481 atccaaagaa aatcaagt
//
LOCUS       DAMJVG010000114         9451 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.119, whole genome shotgun sequence.
ACCESSION   DAMJVG010000114 DAMJVG010000000
VERSION     DAMJVG010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9451)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9451)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9451
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.119"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            491..1696
                     /locus_tag="PC512_003368"
     CDS             491..1696
                     /locus_tag="PC512_003368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HDF2443087.1"
                     /translation="MSKKVLIMSASTGGGHNRAALAIKEELTSKTLDGEPIECEIIDS
                     LKLVNNTMDKIISRGYEKSAIYTPKAYGSVYRLSETNLLSKNEFKDNLLITFMAKKFK
                     KLIRSEKPDLIIGTHPFPMIALSTLKKNFNLHNNESNAYTEHFYKHYTNTINVPPLIS
                     VLTDYTTHSTWIQNEIDYYIVGHEYVKELLVFDGVEPSKIRTFGIPVEKSFLSHRDKD
                     IVLSELNLSPDKLTVLLMGGSFGAGNIKETLDELLDTDRDFQILVITGKNESLKEKIE
                     KKLMSRYHDKNVCVLGYTDKMNDILASIDVLVSKPGGLTTTEALLKDVPMIVPYYIPG
                     QEEENLDFLSNCGAALRTTKKYNLSILLKVLIDDPSRLEMLKRNIKSIRKSNSAQNIA
                     NLILNIISG"
     gene            complement(1767..1988)
                     /locus_tag="PC512_003369"
     CDS             complement(1767..1988)
                     /locus_tag="PC512_003369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443088.1"
                     /translation="MKPIMNLEEHNAMKEKRVKKMKSKDKPKYDDFEDISFSNKKKTK
                     KNVRNKNAEFRNNYKNYQYDYEEDFYEPI"
     gene            complement(2129..2728)
                     /gene="recR"
                     /locus_tag="PC512_003370"
     CDS             complement(2129..2728)
                     /gene="recR"
                     /locus_tag="PC512_003370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012634696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HDF2443089.1"
                     /translation="MQVYTGPITRLIEEFSKLPGVGRKTAQRLAFHIINMNTNDVEAL
                     SKAIIDAKREIRYCSICCNITDTDPCSMCSNKSRDSSVICVVEDPRDVAAMERTREFK
                     GQYHVLNGVISPMDGIGPDMLKIKELIQRLGNQEVKEIIMATNPTIEGEATAMYIARL
                     VKPMGIKVTRIAHGLPVGGDLEYADEVTISKALEGRREI"
     gene            complement(2741..3091)
                     /locus_tag="PC512_003371"
     CDS             complement(2741..3091)
                     /locus_tag="PC512_003371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HDF2443090.1"
                     /translation="MAKKGFGGGMMPGGGNMNNLLKQAQKMQENMQKAQQELESKEVE
                     ASVGGGAVTVKVNGKKEVIDITIKPEVVDPDDIEMLQDLVLSAVNQALRNIDDIQASQ
                     MSKVTGGMNIPGLF"
     gene            complement(3150..4787)
                     /gene="dnaX"
                     /locus_tag="PC512_003372"
     CDS             complement(3150..4787)
                     /gene="dnaX"
                     /locus_tag="PC512_003372"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HDF2443091.1"
                     /translation="MHKALYRAYRPQKFEDVIGQDHIIKTLKNQIYSDNIGHAYLFCG
                     TRGTGKTSTAKIFSRAVNCLNKINEEPCNECEICESVLKDNTMDVVEIDAASNNSVDD
                     IRELRESVKYSPANAKYKVYIIDEVHMLSQGAFNALLKTLEEPPSYVIFILATTEPHK
                     IPATILSRCQRYDFKRVTVKDMTLRMKKICEDEGIDIDDKALNLIARNSQGALRDALS
                     ILDQCMSFGESKIDYKDVVELMGSVNIEQLFELSQCIVEQDTKKSLEILNEFVLWGKD
                     IRNLINDLIDHFRNLMVCKVSSELDEIISLPEETIEQLKIQSKNIDINDLIRILNILS
                     ITQDDIKSSSNPRVLVEITIMKIAQPMFDESKEALIKRVENLEKMIELGNFKSEKIGN
                     NKEKEYEVDREIDVKQENVVYEDVKNEDVILIESSWKNILKQIKKDKKMPIYALLSEV
                     KSFNVYSNMLYVIFDDKFDFAKTRLSSQDTINYLEKTIRDVLNRSFNVKIVLTSEVKD
                     INLEVKEKKDIGEEILKNIVSEEILEIKDSIDENESK"
     gene            complement(4864..5128)
                     /gene="ffs"
                     /locus_tag="PC512_003373"
     ncRNA           complement(4864..5128)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="PC512_003373"
                     /product="signal recognition particle sRNA large type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01854"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF01854"
     gene            complement(5166..5257)
                     /locus_tag="PC512_003374"
     tRNA            complement(5166..5257)
                     /locus_tag="PC512_003374"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5221..5223),aa:Ser,seq:gga)
     gene            complement(5258..5713)
                     /locus_tag="PC512_003375"
     CDS             complement(5258..5713)
                     /locus_tag="PC512_003375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HDF2443092.1"
                     /translation="MESSFYMKEALKEAYKAYNKKETPIGAIIVKDNQIIARAHNLTE
                     TLKDSTAHAEILAIKQASEKLGGWRLTDCDLYVTMEPCIMCSGAIVNSRIKKLIIGTR
                     HVKNSYIEKQHEFKLDYFNNNNVKVAFDVLQEECSIILQEFFKALRKRD"
     gene            complement(6034..7305)
                     /gene="serS"
                     /locus_tag="PC512_003376"
     CDS             complement(6034..7305)
                     /gene="serS"
                     /locus_tag="PC512_003376"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HDF2443093.1"
                     /translation="MLDIKRIRENLDDIKKAMERRGEREFDLDAVVELDNKRREILQE
                     VEVMKNELNVNSKKIPQLIKEGKDVTEEKARLKELSDKIKGIDEKVKEVEAKMEYTLM
                     RIPNVPHPEVPQGETDEDNVQIRTWGEPTKFDFEHKAHWDIGTGLGILDFERAGKITG
                     SRFTLYRGLGARLERSLMNFFLNTHTAKHGYTEVLPPFMANRNSFIGTGQLPKFEEDM
                     FKIEGLEYFLIPTAEVPVTNIHANEILDVAELPIKYCAYTPCFRSEAGSAGRDTRGLV
                     RQHQFNKVELVKFVKPEDSYNELESLTHDAETMLQMLGLPYRVVKICTGDLGFTAAFK
                     YDLEVWMPSYNRYVEISSCSNFEDFQARRAGIRFKRDKKSKAEYVHTLNGSGLAIGRC
                     LAAILENYQQADGSVVVPEELRPYMGVDVIK"
     misc_binding    complement(7431..7636)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(7764..8645)
                     /locus_tag="PC512_003377"
     CDS             complement(7764..8645)
                     /locus_tag="PC512_003377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HDF2443094.1"
                     /translation="MNFLSLAKTASTNSNITKRTLENMLDNFSDNIPNIIYAIIVFVI
                     GIYISKIVRRMVSKFLIKYGMSKGVNNFIVYGIYISMLSIISLISLGIIGIQTTSVVA
                     VLGAAGFSIGLAFKEILSNLGSGMIILFFKPFNIGDYIQGSGVEGTVSDIQIFSTVLK
                     TPDNKTIIIPNFQLTSNNIINYTHQNKRRIDFSYNISYDSDIDVVKSILNEIFTNEKR
                     ILNDPKPIIGLNSIGNNTMQIVARPWVKTDDYWDVYFDVMEKVKNKFDENDIKVPFVP
                     SSLLFNNTGNLNTMDKR"
     gene            complement(8657..9166)
                     /locus_tag="PC512_003378"
     CDS             complement(8657..9166)
                     /locus_tag="PC512_003378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HDF2443095.1"
                     /translation="MNSNERRSKLIDILKESKHPVKGGTLAELLNVSRQVIVQDIALI
                     RARGFEIIATPQGYIIYNQPYFTKQIKCKNHKDSKEIYDELKIIVDLGGIIKDVIVNH
                     PTYGQITAELNIYSKMDIDNFMKKVETNEFKQLSVLTECSHIHTIEAIKEETIEAIVK
                     ELKDNGILS"
     gene            complement(9292..9408)
                     /gene="rrf"
                     /locus_tag="PC512_003379"
     rRNA            complement(9292..9408)
                     /gene="rrf"
                     /locus_tag="PC512_003379"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         3007 a         1655 c         1013 g         3776 t
ORIGIN      
        1 ctcagatact attgttatca aaatatctgg ctttatggtt tgtttcttaa tataaattaa
       61 cctactgttt aattttcaat gttcgtgttt atttcttttt ccttttttca aggacaagta
      121 atactatatc atctttatct attctagtca atataatttt ttactttttt taattttttt
      181 atttatcatg tattctttat ctttaatttt taaaacttaa tgctaagtaa acctgtttat
      241 ttcataaaac taatatatat tctatgctct attttccttt ttattctata tttaaatttt
      301 ttatttacaa gaatattttt aatataacat atttgataaa attaatttac atttctttca
      361 cttgtaattt ttgcaatctt gtattagatt aatattaaaa ataatttatc aataacctta
      421 ttcacaaaga cagtttttat atatcaaaat ataatataaa tactatgcta cattttagga
      481 ggattttatt atgagcaaaa aagtattaat aatgtctgct tccactggtg gtgggcataa
      541 tagggctgct ctagctatta aagaagaact tacttccaaa acacttgatg gagagccaat
      601 tgaatgtgaa ataatagata gtttgaaatt agttaataat acaatggata aaataatttc
      661 aagaggatac gaaaaatctg ctatatatac tcccaaagcc tatggaagtg tatatagatt
      721 atctgaaaca aatcttttgt caaaaaatga atttaaagat aatctactaa taacattcat
      781 ggctaaaaaa tttaaaaagc ttattagaag cgaaaaacca gacttgatta taggaacgca
      841 tccttttcca atgattgctc taagtacatt gaaaaaaaac tttaatttac ataataatga
      901 atcaaatgct tacacagagc atttttataa acattataca aataccatta atgttcctcc
      961 gcttatttct gtattaaccg attatactac tcattctaca tggatacaaa atgaaattga
     1021 ttactatatt gttggtcatg aatatgtaaa agaattattg gtgtttgatg gagttgaacc
     1081 gagtaaaatt agaacatttg gaatccctgt tgaaaaatct tttctctctc acagagataa
     1141 agatattgtt ctttctgagt tgaatttatc tcctgataaa ttaactgttt tacttatggg
     1201 gggtagcttt ggggctggaa atataaaaga gacacttgat gaattactgg atactgatag
     1261 agactttcaa atacttgtaa ttactggtaa gaatgaaagc ctaaaagaaa aaatcgaaaa
     1321 aaaacttatg tctcgttatc atgataaaaa tgtatgtgtc cttggataca ctgataagat
     1381 gaatgatatt ttagcttcta tagatgtatt agtaagcaaa cctggtggac ttactacaac
     1441 tgaggctctt ttaaaagatg tacctatgat agttccttat tatataccag gtcaggaaga
     1501 agagaatctt gatttcttat ctaattgtgg tgcagcactt agaactacaa aaaaatataa
     1561 cttgtcaata ttactaaaag ttttaataga tgaccctagc agattagaaa tgctaaaaag
     1621 aaatattaaa tcaataagaa agtcaaattc agcccaaaat atagctaatt taattttaaa
     1681 tataatttct ggttgataaa ataaataaaa tccctatagt atatatatta tctattaggg
     1741 attttttatt ttctaattat ttaatattaa attggctcat aaaagtcttc ttcataatca
     1801 tactgataat ttttataatt atttctaaat tcagcatttt tatttcgtac atttttttta
     1861 gtttttttct tattagaaaa acttatatcc tcaaaatcat catatttagg tttatctttt
     1921 gatttcattt ttttaactct tttttctttc attgcattat gttcttctaa gttcataatt
     1981 ggtttcatgt tgcaccccta tcaaaatttt taaatgattt atacaacaaa ttatacaata
     2041 cagaagaaat ttattcaata aatctaaatc aaaattaatt tgaatttaac tcaaaaaact
     2101 acaaaaatcg aggtattaac ctcgattttt atatttctct tctgccttct agtgcttttg
     2161 atattgtgac ctcatctgca tactctaaat cgcctccaac aggaagacca tgagctatcc
     2221 gagtgacttt gattcccatt ggttttacta acctagcaat atacatggct gtagcttcac
     2281 cttcaatagt aggatttgtt gccattatta tttctttgac ttcctgattg ccaagtcttt
     2341 ggataagttc ctttattttt aacatatctg gtccaattcc atccattgga gaaattactc
     2401 catttaatac atgatactgt cctttaaact ctctcgttct ctccatagct gctacatctc
     2461 ttggatcttc cacaacacat ataacacttg aatctctact tttatttgaa cacatgctac
     2521 atgggtctgt atctgttata ttacaacaaa ttgagcaata tcttatttct ctttttgcat
     2581 ctataatcgc tttagataaa gcttccacat cattagtatt catattaata atatgaaaag
     2641 ccaatctttg agcagtcttt cttcctactc caggaagctt tgaaaattcc tctataagtc
     2701 tcgttatggg acctgtataa acttgcataa ataccaccta ctagaataac ccaggtatat
     2761 tcatacctcc agttacctta ctcatttgac ttgcttgtat atcatcaata tttctcaatg
     2821 cttgatttac tgcacttaaa actaaatctt gtagcatttc tatatcatct ggatcaacta
     2881 cttctggctt gatagttata tctataactt cttttttacc attaactttt acagtaactg
     2941 ctcctccacc aactgaagct tctacttctt tactttctaa ctcttgttga gctttttgca
     3001 tattttcttg cattttttga gcctgcttta acaagttgtt catatttcca ccaccaggca
     3061 tcattccgcc tccaaaacct tttttagcca taaacactat tcctcctaaa cttattttca
     3121 ttttattatt atatcataat agtattttat tatttactct cattttcatc aatactatct
     3181 tttatttcta atatctcttc actcactatg ttctttaata tttcctcacc aatgtccttt
     3241 ttctctttaa cttcaagatt tatatcttta acttctgatg tcagtactat ttttacatta
     3301 aaacttctat ttaaaacatc tcttattgtt ttttctaaat aatttattgt atcttgagag
     3361 ctcagtctag tttttgcaaa atcaaattta tcatcaaata taacatacaa catattagaa
     3421 tatacattaa aactttttac ttcacttaag agtgcgtata ttggcatttt tttatctttt
     3481 ttaatttgtt taagtatatt cttccaagat gactctataa gtataacatc ctcatttttt
     3541 acatcttcat aaactacatt ttcttgtttt acatctattt ctctatcgac ctcatactct
     3601 ttttctttat tattcccaat tttttcagac ttaaagttcc ccagttcaat cattttttct
     3661 aagttctcaa ctctttttat aagagcttct ttactttcat caaacattgg ttgagcaatt
     3721 ttcattatgg ttatttccac taaaaccctt ggatttgaag atgactttat atcatcctga
     3781 gttattgata atatatttaa aatccttatt aaatcattta tatctatatt tttagactga
     3841 attttaagtt gttctatagt ttcttctggt aatgaaatta tttcatccaa ttctgatgaa
     3901 accttacata ccattaaatt tctaaaatga tcaattaagt catttataag atttcttata
     3961 tctttgcccc ataagacaaa ttcatttaat atctcaagag actttttagt gtcctgctct
     4021 acaatacatt gagacaattc aaataattgt tctatattta cgcttcccat taattcaaca
     4081 acatctttat aatctatctt actttctcca aaagacatac attggtctaa tatactaagt
     4141 gcatctctaa gagctccttg agaatttcta gctattaaat taagagcttt atcatctata
     4201 tcaattcctt catcttcaca aatctttttc attctaaggg tcatatcttt aactgtaact
     4261 cttttaaaat cgtatctttg gcatcttgat aaaatggttg caggtatttt gtgaggctct
     4321 gtagttgcta atataaaaat tacatatgat ggaggttcct ctaaggtctt taataatgca
     4381 ttaaaagctc cttgagacaa catatgaact tcatctatta tatatacttt atatttagca
     4441 ttggctggag aatatttcac actttctcta agctctctta tatcatctac actattattt
     4501 gaagctgcat ctatttctac aacatccatt gtattatctt ttaatacaga ttcgcatatc
     4561 tcacactcat tacacggttc ttcatttatt ttattcaaac agtttactgc tcttgaaaaa
     4621 atctttgcag tagatgtttt accagtacct cttgttccac aaaacaaata agcatgtcct
     4681 atattatcac tatatatttg attctttaaa gtcttaataa tatgatcttg accaataaca
     4741 tcttcaaatt tttgtggtct atatgctcta tataatgctt tatgcatctt tttacctctc
     4801 tttagcaaaa ttaataaaaa aatccctcat tatctaaggg attagtcttt tatatattaa
     4861 atgctgtaca ccatctatcg acttaattcc ataggcgtta ccaaaacagt tagctcaact
     4921 taggcacccc cacggcacac aaaagtgatc acttaccgct gcttccttcc ggatctgacg
     4981 gggttcatga gctttcattg cgcaggacct aagcatcaac accacttatt tagggcggcc
     5041 ctacagaaaa taagccttta gatggaattc aatcctgcta tagcggattg caggttacag
     5101 ggcaccgcta cctccccatc tagtacagca aaattacaac catatttaat tactttcatt
     5161 gtttctggcg gagagagtgg gatttgaacc cacgatacag ttttacccat atactcgctt
     5221 tccaggcgag cgccttcgac cactcgacca tctctcctta atctcttttt ctcaatgcct
     5281 taaaaaattc ttgcaatatg atcgagcatt cttcttgcaa aacatcaaaa gctactttta
     5341 cattattatt attaaaataa tctaatttaa actcatgctg tttttctata tatgaatttt
     5401 ttacatgtct tgtccctatt ataagctttt ttattctaga attaactatt gcgccactac
     5461 acattatgca aggttccatt gtaacatata aatcacaatc agtcaacctc caaccaccta
     5521 atttttctga tgcttgtttt atcgctaaaa tttctgcatg tgccgtagag tcttttaacg
     5581 tttctgtaag gttatgagct ctagctatta tttgattatc tttaactata atagcaccta
     5641 ttggtgtttc ttttttatta tatgctttat atgcttcttt taatgcttct ttcatataaa
     5701 atgaactttc cataattcct cccaaaactt ataacaaact tatcttatca taattcattt
     5761 tataattcaa cttaatttta ttttgtttat ttaattatta ctatatatag ctatattttt
     5821 tttaaattag ttctaaaata atttttagat attcatacaa gagtgtttta taaaaatatt
     5881 tagtgtttta tgatgaaaat tctgctgtgt aaattaacat aaaaaaacta tgaaattaat
     5941 atttataata atttcatagt ttttttattt attgtttact cataatatat tctcttcatc
     6001 aaagcatact ctacatatac aattaatata aatttatttt ataacatcaa cacccatata
     6061 aggtcttaat tcttctggaa ctactacaga accatctgcc tgctgataat tttctaatat
     6121 agcagccaaa catcttccta tcgctaatcc agaaccattt aatgtatgaa catattctgc
     6181 ttttgatttt ttatcccttt taaatcttat tcctgctctt cttgcttgga aatcttcaaa
     6241 atttgaacaa gaagatattt ctacatatct attgtagctt ggcatccaaa cttctaaatc
     6301 atatttaaat gcagctgtaa atcccaaatc tcctgtacat atttttacaa ctctatatgg
     6361 aagacctaac atttgtaaca tagtttcagc atcatgagtt aatgattcta attcattata
     6421 agaatcttct ggtttaacaa atttaactaa ttcaacttta ttaaattgat gttgtctaac
     6481 taaacctctt gtatctcttc ctgctgaacc tgcttcagat ctaaaacaag gagtatatgc
     6541 acagtattta attggaagct ctgcaacatc taatatttca ttagcatgta tattagtaac
     6601 aggaacttca gctgttggta ttaagaaata ctctaatcct tctattttaa acatatcttc
     6661 ttcaaattta ggaagttgac cagtccctat aaaactattt ctattggcca taaatggagg
     6721 taagacttcc gtatagccat gcttagctgt atgagtattt aaaaagaaat tcattaaaga
     6781 tctttctaat ctagctccta atcccctata taaagtaaac cttgacccag ttattttccc
     6841 tgctctttca aaatctaaaa tacctagacc tgtacctata tcccaatgcg ctttatgctc
     6901 aaaatcaaat ttagtaggtt ctccccaagt tcttatttga acattgtctt catctgtttc
     6961 accttgtggt acctctggat gaggaacatt tggtattctc attaatgtat attccatttt
     7021 tgcttctact tcttttactt tctcatcaat accttttatc ttatctgata actctttcaa
     7081 tcttgccttt tcttctgtta catcttttcc ttcttttatt aattgaggta tttttttaga
     7141 atttacattt aactcatttt tcataacttc aacttcttga agtatttctc ttcttttatt
     7201 atctaattcc actacagcat caaggtcaaa ttctctttca cctcttcttt ccatagcttt
     7261 tttgatatca tctagatttt ctcttattct tttaatatct aacatattaa ttcctcctaa
     7321 taattttgat aatataagtt ataattccaa cttaatttac aaacattata cttgtaaact
     7381 cttagtttaa acaaatttta aaaataaaaa aagacctccg tttaccctat aaaagggacg
     7441 aaaatctttt atccgcgttg ccaccctaat tgactatact aaaatgtata atcctctcag
     7501 acctataacg taggtaaacg tctagcttta actagaagct ctagagtaga ttcaaaaacc
     7561 attgtaatga gttttcacca tccactcatt ctctgaatac aatctgtttt ttactatttt
     7621 ccttcacagc tttttaacta attgttttat ttgataatca ttatattata tatattaaca
     7681 tctttcaata ctattattca aattttttta gaattttctt taatttttta tattaaattc
     7741 attttttcta tttaattaag accttatctt ttatccattg tatttagatt acctgtatta
     7801 ttaaataata atgaagaagg aacaaatgga acttttatat cattctcatc aaatttattt
     7861 tttacctttt ccattacatc aaagtataca tcccagtaat catcagtttt tacccaaggt
     7921 ctagcaacta tttgcatggt gttatttcct atagagttta gacctattat aggctttgga
     7981 tcatttaata ttcttttttc gtttgtaaaa atttcattta atatagactt aactacatct
     8041 atatcactat catatgaaat attatatgaa aaatctattc ttcttttgtt ttgatgtgtg
     8101 taattaatta tattattact tgtcagttga aaattaggta taattatagt tttattatct
     8161 ggcgtcttaa gaacagtgct aaatatttgt atgtcagaaa ctgtaccttc tacacctgaa
     8221 ccttgaatat aatcacctat attaaatggc ttaaaaaata aaataatcat accagagcct
     8281 aaatttgata atatttcttt aaaagctaaa cctatactaa atccagcagc tcctaacaca
     8341 gctacaactg atgtagtttg tatccctata atacctaagc ttatcaatga tataatagat
     8401 aacatagata tatatattcc atatacaata aaattattta cacctttact cattccatat
     8461 ttgattagaa actttgaaac catccttctt actattttag atatataaat acctatcaca
     8521 aatacaatta ttgcatatat aatatttggt atattatcac taaaattatc gagcatattt
     8581 tctaaagttc tcttagttat attgctattt gttgaggcag tcttagccaa tgataaaaaa
     8641 ttcattcaac tcctccttat gataatattc cgttgtcctt taactctttt actatagctt
     8701 ctatagtttc ttcttttatt gcctcaattg tatgaatatg gctacattct gtcagaaccg
     8761 ataattgttt aaattcattt gtctcaactt tcttcataaa gttgtctata tccattttag
     8821 aataaatatt aagttctgca gttatctgac catatgttgg atgatttaca ataacatctt
     8881 ttataatacc acctaaatct acaattatct ttaattcatc ataaatttct ttagaatcct
     8941 tatgattttt acactttatt tgttttgtaa aatacggttg attatatatt atatatcctt
     9001 gaggtgtagc tattatttca aatcctctag ctcttataag ggctatatct tgaactatta
     9061 cttgcctact tacatttaat agttcagcta gtgttccacc ttttacagga tgcttagatt
     9121 cttttaaaat atctattaat ttacttcttc tttcattaga attcatatta caccttcttt
     9181 ccaaataaaa actttaccta tactatataa ttttatattt tatcttatta taaatcaata
     9241 ttgactttat attctattta atcttaactt ttataataaa taaaaaagac tacgtggcta
     9301 cgtcctactc tcccaggcag tttcccacca agtaccatca gcgctagaga gcttaacttc
     9361 tgtgttcgga atgggaacag gtgtatcctc tctgctattg taaccacata atctttatgc
     9421 ttaatatttc tattaagttt ttaataagtt t
//
LOCUS       DAMJVG010000115         9342 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.120, whole genome shotgun sequence.
ACCESSION   DAMJVG010000115 DAMJVG010000000
VERSION     DAMJVG010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9342)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9342)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9342
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.120"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(<1..1262)
                     /locus_tag="PC512_003380"
     CDS             complement(<1..1262)
                     /locus_tag="PC512_003380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HDF2443096.1"
                     /translation="MLKVLKGNIIFTKTSETFTVFENSYIILEKGKVKGIFKEIPKEY
                     KNLKVVDYTDKLIIPGMNDLHAHASQFKNLGMAMDKELLPWLETYTFPEESNYKDIEY
                     ATKMYKKFVKELWKSGTTRIAVFATVHKEASMKLMDIFKEVGLGAYVGKVNMNMNCPD
                     TLLENTQDSITDTEEIINKYSDTDSIVKPIITPRFIPSCTSELLKGLGDLCLKYNIPI
                     QSHLSENYDEIEWVRSLEPESKFYGDAYNRYNLFGQTPTLMAHCVHCSQDEIDLMREN
                     NVMAVHCPASNFNVGSGAMPIRKLIDNNIRLALGSDISGGHTLSIFKAMVSAIQLSKL
                     YWVNSGKKYNFLSLSEAFYIATKSGGSFFGKVGSFEEGYDFDALIIDDSNLNHDNYSI
                     LERLERFIYVGDDRNIIHRYVCGKLIEEP"
     gene            1474..1713
                     /locus_tag="PC512_003381"
     CDS             1474..1713
                     /locus_tag="PC512_003381"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443097.1"
                     /translation="MECYLKRTLIIFSEAFLSISFKTRKYLFIVIFILVCPNLSEMIF
                     ILVPARRRIIRIDNIVSIYKYVGVLKLINYSILIL"
     repeat_region   1909..3058
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=1909..1937
                     /rpt_unit_seq="gttttatattaactatgtggtatgtaaat"
     gene            3467..3754
                     /locus_tag="PC512_003382"
     CDS             3467..3754
                     /locus_tag="PC512_003382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443098.1"
                     /translation="MKKILYALYSFIVIIANFRLKEKNYNFILLAIFFILLLIQNGVL
                     KTGYQNRATFYQDNYFNGEDKNDKIKFMTIKIFIFLSLPLCFNILFNYLTS"
     gene            complement(4293..4844)
                     /locus_tag="PC512_003383"
     CDS             complement(4293..4844)
                     /locus_tag="PC512_003383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2443099.1"
                     /translation="MSINTVIAKNLNRLRNERNLSLGQLAELSGVSKVMLSQIEKGDS
                     NPTVNTIWKIASGLNVPYTAILEQPQNETFIVSKTDIDVQVSENKDYRLYCYYPNTPT
                     RNFELFQMELEEGHSYTSVGHSEKSQEYIMIIEGQLKLEVNDSIYQLRENDSICFSAE
                     SIHTYHNQGEKTLKAVIINYYPV"
     gene            5035..5997
                     /locus_tag="PC512_003384"
     CDS             5035..5997
                     /locus_tag="PC512_003384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HDF2443100.1"
                     /translation="MRVLNNVTEAIGNTHMLHLSKIADEFGVQGNIYAKMEYLNPGFS
                     KKDRVALQMITEAENAGLLVPGQAVVELTSGNTGTGLAIACACKGYKFIACMSKGNSM
                     ERARMMKALGAEVVLVDQMPNSVHGQVSGEDLALVEIEAQKIAKERNAFRADQFNLEA
                     CNHAHEKYTAEEMWEQLDGNIDVFVDFLGSGSTFAGCSKTLKKHNSSIKCYVVEPETA
                     AIYSGKEITDQGHKIQGGGYSMDLPLVDKKLIDGYIQVTDEEATDVARKLAKLEGVFA
                     GFSSGANVCAAIKLLKSSEKGKNIVLTLNDSGLKYLSTDLYEEL"
     gene            6292..8136
                     /locus_tag="PC512_003385"
     CDS             6292..8136
                     /locus_tag="PC512_003385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HDF2443101.1"
                     /translation="MQKRILRNFIFTGKNILSKLVFIIKYNFSTLILFELFHKGLALF
                     FIWPSIRYIFDILIKSLHIVYLNMDNFIKVLTNPMSIVLIILSVIILAFYAFFEFTSV
                     IICFNKSIKYEKIGLFELFKISFENSIKLLYPKNILLFIFVILIIPLVNTVLISGFIG
                     KIQIPEYILDYIKSDIILNIIYMIFLLIIYISVIRWIFSIHEITLNTENFKRARKESV
                     NLIKGKIIRTIIYSLILSLVVAIIGYAIYHSGIIFIGIWTKYCTDMEFLKNVFINRCI
                     AFEEYFRLILSIFIFILDIGFISATYYQYKGVNISKNNIKKEKKSISKIVFNLVLILL
                     ISYIESVAFSSHINGMFNTSFSFYTTAIAHRAGAEMAPENTLAAIEEASHAKADYAEI
                     DVQETKDGELIVLHDSNFKRTTGVDKNVWDVNYNEVKTYDAGSFYYYGKGYYDEKFVG
                     EKIPTLKEMIKYSKGKVKLLIEIKLNGHEKGDVVKKVVQLIKENNFENQCIVASMDKT
                     ILQKVKKLDENLLTCYFMAIAYGDFSKLNYVDIYGIESTFVNKTVVEKIHKMNKKIFV
                     WTVNSDSLIEKMLDLNVDSIITDNPYLIESAIYWKKNGFISQVSDYLF"
     gene            8458..9042
                     /locus_tag="PC512_003386"
     CDS             8458..9042
                     /locus_tag="PC512_003386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HDF2443102.1"
                     /translation="MTEREKMLAGELYDCGDIELLTQWHKAKDLVRDYNQTDSLDLEK
                     KEKILNELLGGKGKNLWITAPYYVDYGNNIYFGNNCEVNMNCTFLDDNKIIIGDNALI
                     APNVQIYTAFHPTNAGDRFGNAKEDGSFEFCKTQTAPVTIGDNVWIGGGAIIMPGVTI
                     GDNVVIGAGSIVTKDIPSNMIAYGNPCRIIRENK"
BASE COUNT         3518 a          999 c         1367 g         3458 t
ORIGIN      
        1 ggttcttcaa ttagttttcc acatacatat ctatgaatga tatttctatc atcaccaaca
       61 tagataaatc tttcaagtct ttcaagtata gaataattgt catgatttaa atttgaatca
      121 tcaataatca atgcatcaaa atcataacct tcttcaaagc taccaacttt tccaaagaaa
      181 cttccaccac ttttggttgc aatataaaaa gcctcagata aagataagaa attatacttc
      241 ttaccagaat taacccaata taatttagat aattgtattg cagataccat tgctttaaat
      301 attgacaatg tatgtccacc gcttatatct gatccaagtg ctaatctaat attattatcg
      361 attaattttc tgataggcat agcaccacta ccaacattaa agttagaagc tggacagtga
      421 actgccataa cattattttc tctcattaaa tctatttcat cctgagaaca atgaacacaa
      481 tgagccatta aagtaggagt ttgaccaaat aaattatatc tattatatgc atctccatag
      541 aatttagatt caggttctag acttctaacc cattcaatct catcataatt ttcagataag
      601 tgtgattgaa taggaatatt atattttaaa cataaatctc ctaaaccttt taaaagttca
      661 cttgtacagc ttggtataaa tctaggtgtt attattggtt ttacaataga atctgtatca
      721 ctatacttat ttataatttc ttctgtatca gtaatagaat cctgagtgtt ttctaataaa
      781 gtatcagggc aattcatatt catatttact ttaccaacgt atgctccaag accaacttct
      841 ttgaatatat ccataagttt catagaggct tctttatgta ctgttgcaaa cactgctatt
      901 cttgtagttc cagatttcca aagttctttt acaaattttt tatacatttt tgttgcatat
      961 tctatatctt tataatttga ttcttctgga aatgtataag tttcaagcca tggcaaaagc
     1021 tctttatcca tagccattcc aagattttta aattgagagg catgggcatg gaggtcattc
     1081 ataccaggta ttataagctt atcagtgtaa tctactactt ttaggttttt gtattcctta
     1141 ggtatctctt taaatattcc ctttacttta cctttttcca gtataatata actattttca
     1201 aatactgtga aagtttctga agtttttgta aaaattatat ttccttttaa tacttttaac
     1261 atataggtct ccttagtttt aaatttgttt taatatatgt aggtaaaatt ttgttttaca
     1321 aatcaaaatt ttaccacatg tattatatca aatctaaact ataaatacta ttagataata
     1381 gcaaatatta gtgaaataca gttgtttact attattatat ataactgaca tttaagtgac
     1441 atttaagaaa aatataatgc ctacttacat aaaatggaat gttatttaaa gagaactttg
     1501 attatatttt cagaagcttt tttatccata tcgtttaaaa caagaaaata tctattcata
     1561 gttattttta tattagtatg tcctaatctt tcagagatga tttttatatt agttccagct
     1621 agaagaagaa ttattagaat agataatata gtaagtattt acaaatatgt aggtgttctt
     1681 aaattgataa attattccat tttaatttta tagtttgaat tttatgatat aataaaaata
     1741 tataaatttt gcagtgagcg atatttttga taaagtaggg tttaacagtt gcaatgtaag
     1801 ggattgaggg tgtgtgataa atgttatcaa ttgcactact catggttcac tgcaaatttg
     1861 agagagttgt atgtgtgtaa gtactgaaaa tacttagttt attttggggt tttatattaa
     1921 ctatgtggta tgtaaatagc agttaaagtt gcaaacatca acttaacagg aaaagtttta
     1981 tattaactat gtggtatgta aattccaaaa ttttaacttt ttctttttct aaatctttat
     2041 gttttatatt aactatgtgg tatgtaaatt ttaaattata aaaagtatac aaacgaaaat
     2101 tatcaacgtt ttatattaac tatgtggtat gtaaattaac ctctcctgta cgtttatcta
     2161 tgtactcatt aggttttata ttaactatgt ggtatgtaaa tctctttagc gcttcttcaa
     2221 gttgtatttg tgtataagtt ttatattaac tatgtggtat gtaaatttca tattccaagc
     2281 gttttgctta cacttaatag aagttttata ttaactatgt ggtatgtaaa taaaattaaa
     2341 tttcatgctc ttagacatac atatgcaacg ttttatatta actatgtggt atgtaaatta
     2401 gattgctttc aaattacctc ttgtatagcg tcttgtttta tattaactat gtggtatgta
     2461 aatctttttt tattagtgaa agggggtggt taaaattaaa gttttatatt aactatgtgg
     2521 tatgtaaatt tgctccgcta tgccttgcgc tctctaatat cgcttagttt tatattaact
     2581 atgtggtatg taaatggttt taaagaccca gcaacgataa aacaatatgt tgcaagtttt
     2641 atattaacta tgtggtatgt aaattgaact ttaatcggtt ttatacaaca atataacgcg
     2701 ttttatatta actatgtggt atgtaaataa tgaaggtata ataaaattaa cagaagaaac
     2761 aagagagttt tatattaact atgtggtatg taaattcaca catgagcaat atcgaaacag
     2821 gcaaatctac aggttttata ttaactatgt ggtatgtaaa tttcgtaaaa taacaattat
     2881 ctggaatatg agaagttgtt ttatattaac tatgtggtat gtaaatcact cttaagttgt
     2941 gacctatctg atatatgatt aaagttttat attaactatg tggtatgtaa attcaatatc
     3001 tatattaagt ttatttttaa aaacatcttg ttttatatta actacgtggt atgtaaattt
     3061 gcaacaagta taggtaaaat accccaataa tttatacagc attttatcct ttaaaatata
     3121 attatttttt agcatttgta gtaaataatt accagataac attgacttta gttttaatga
     3181 ttaaaatata aaagtagaat aattataaaa agtattgaaa aatttataaa tatatataat
     3241 aaaacttaat gacaagatat tagatataaa aaataattac cttataaata gattgaaatt
     3301 tatgaatatt catactataa tttaaatata aggagatgcc ctttgaaaat aaaaattaaa
     3361 aaatatttaa tgctactaca ataggaacta gaactacact taataaatat acagaaatta
     3421 gatttggctc aatataaaat acaaatatag aatttaggtg ttttttatga aaaaaatttt
     3481 atatgcttta tatagtttca ttgttattat agctaatttt agattaaaag aaaaaaatta
     3541 taactttatt ttattagcaa tcttttttat attgctgtta attcaaaatg gagttttaaa
     3601 aacaggttat caaaatagag ctacatttta tcaagataat tattttaatg gagaggataa
     3661 aaatgataag ataaaattta tgactataaa gatttttata tttttgtcat taccattatg
     3721 ttttaatata ctattcaatt atttaacctc ttaaattata tttagatata ggagtcttat
     3781 gataaaagta agcttatgtg ttatttgtag taaatataaa gtgcatatag tgataaaaca
     3841 aaagtttcat ataaatgaag aaaaaaatat aaaataattt atttaactac ttaaaaataa
     3901 actaaaaggg ataataaaat agcttttagt ttatggtaat agaggtattt aaaaagagtg
     3961 cataagcact ccaattgtga gaaatacata cacaaatcat tattacaaca atgaaaaatg
     4021 tacatataag agacgttttg tatttgtttt aagtgataat attttaatac taactaaata
     4081 attatcacaa tggtaaaaaa gaaaaaggag tattttgtac tccatttgtc aaaaatataa
     4141 aacttttata taagcttatt ataacataat tgataaaagt gtaaagatat ataatgaatt
     4201 tataaagaaa aataaaataa aaaagataaa tcctaatcaa aggatttatc tttttgtata
     4261 gaaaataatt attctattat taaatggcat ggctaaactg gataataatt tattattact
     4321 gctttcaatg ttttttctcc ttgattatgg tatgtatgaa ttgattcagc tgaaaaacaa
     4381 atagagtcat tttctctaag ttgataaata gagtcattta cttctaattt taattgacct
     4441 tctataatca taatatattc ctgtgatttt tcagaatgac caacagatgt ataactatga
     4501 ccttcttcta attccatttg aaataattcg aagtttctag ttggtgtatt gggataataa
     4561 caataaagac gataatcttt attttctgaa acttgtacat ctatatcagt ttttgataca
     4621 ataaaagttt cattttgagg ttgttccagt attgcagtat atggaacatt tagtccactt
     4681 gcaattttcc aaattgtgtt tactgttggg tttgagtctc ccttttcaat ttgagaaagc
     4741 attactttac ttacgccaga taattcagca agttgaccta gacttaagtt acgttcatta
     4801 cgtaatctat ttaaattttt agcaataaca gtattaatac tcatagtagc tccttaaaat
     4861 gtaaattatt gacaaatata atttacgaat gtataattta tttaacatta tttataattt
     4921 acaaatgtat aatataatga acgttaaata cactgtacat ccgtaatata aattatactg
     4981 cataaagagt tgtttttcaa cggatgatag ttgagagatt aagggggaat tgtaatgcgt
     5041 gtacttaata atgttacaga ggctataggc aatactcata tgttacattt atccaaaata
     5101 gcagatgaat ttggagttca aggtaatatt tatgcaaaga tggaatactt aaatccggga
     5161 tttagtaaaa aggaccgtgt agcattacaa atgattaccg aagcagaaaa tgcaggttta
     5221 ttagttccag gtcaagcagt tgtggaatta acaagtggta atactggaac aggactagca
     5281 atagcttgtg catgtaaagg atataaattt atagcgtgta tgtcaaaagg aaattctatg
     5341 gaaagagcaa gaatgatgaa agctttaggt gctgaagtag ttcttgtaga ccaaatgcct
     5401 aattcagttc atggacaggt atctggtgaa gatttggcac ttgtagaaat tgaggctcaa
     5461 aaaatagcaa aagaaagaaa tgcatttaga gcagaccaat ttaatttaga agcttgtaat
     5521 catgcacatg aaaagtatac agcagaagaa atgtgggaac aattggatgg aaatattgat
     5581 gtatttgtag attttcttgg aagtggtagt acttttgcag gatgttcaaa aacacttaaa
     5641 aaacataatt cttctatcaa atgttatgtt gttgaacctg aaacagcagc aatttattca
     5701 ggtaaagaaa taactgacca agggcataaa atacaaggtg gaggatattc tatggatttg
     5761 ccattagtag acaagaaact tattgatggt tatattcaag ttacagacga ggaggcaact
     5821 gatgtagcaa gaaaattagc taaattagaa ggtgtatttg caggattttc ttcaggggca
     5881 aatgtatgtg cagcaattaa gttgttaaag agcagtgaaa aaggaaaaaa tatagtttta
     5941 actcttaatg atagtggttt aaaatattta agtactgatt tatatgaaga attgtaataa
     6001 tagcacaata gttatgcaat gttttttaaa ttaagtatat agatttaaat tataaaaagt
     6061 atctcaatgt aaattttgaa agttataaag gagatacttt tttattttgt aaatatggag
     6121 tatcctactt ataagtatta agctatatag atattgatga ttagctatgc aataaaaaag
     6181 agtatgtgtt tttgcattta tacatcataa cttggaataa tacatattaa tgttctaaat
     6241 gtatttaaaa tatatgataa aattagaaca aatagataca aggagataaa aatgcaaaag
     6301 agaattttaa gaaattttat atttacgggt aaaaatattt taagtaaact tgtttttata
     6361 ataaaatata attttagtac attaatttta tttgaattat ttcataaagg attagcctta
     6421 ttttttatat ggccatctat tagatatata tttgatattt taataaaaag tttacatata
     6481 gtctacctaa atatggataa ttttataaaa gttttgacca atcccatgtc aatagttctg
     6541 ataatactat cagttataat actagctttt tatgcatttt ttgaatttac ctctgtaatt
     6601 atttgtttta ataaatcgat aaaatatgaa aaaatagggt tatttgaact ctttaaaata
     6661 tcatttgaga actctataaa attgttatat cctaaaaata tactattatt tatatttgtg
     6721 atattaataa ttccattagt aaatacagtt ttaatttcag ggtttatagg aaaaatacaa
     6781 ataccagagt acatattaga ttatataaag tctgatataa ttttaaatat aatctatatg
     6841 atttttcttt taataatata tatttcggtt attagatgga tttttagcat tcatgagata
     6901 actttaaata cagaaaattt taaaagagca agaaaagaaa gtgttaatct tataaaggga
     6961 aagattataa gaacaattat ttattcatta atattatctt tagtagtagc tattattgga
     7021 tatgcgattt atcatagtgg aattatattt ataggcatat ggactaaata ttgtactgat
     7081 atggaatttt tgaagaatgt atttataaat agatgtattg catttgaaga atattttaga
     7141 ttgattttat caatattcat ttttatattg gacattggat ttatctcagc aacttattat
     7201 caatataaag gagtaaatat ttctaaaaat aatattaaaa aagagaaaaa atctatatca
     7261 aaaattgttt ttaatttagt attaatatta ttgatttctt atatagagtc agttgcattt
     7321 tcttcacata taaatggtat gtttaatacg tcattttcat tttatacaac agcaattgct
     7381 catagagcag gagctgaaat ggctccagag aatactttgg cagcaataga agaagcttca
     7441 catgctaaag ctgattatgc agaaatagat gttcaagaaa ctaaagatgg agaacttatt
     7501 gtacttcatg attcaaactt taagagaact acaggagtag ataaaaatgt ttgggatgta
     7561 aattataatg aagtaaagac atatgatgcg ggaagctttt attattatgg aaaaggttat
     7621 tatgatgaaa agtttgttgg ggaaaagata ccaacactca aagaaatgat aaaatattct
     7681 aaaggtaagg tgaaattatt aatagaaata aaacttaatg gacatgaaaa gggagacgta
     7741 gtaaaaaaag ttgttcagtt aattaaagaa aataattttg aaaatcaatg tatagttgca
     7801 tctatggata aaactatatt acaaaaagta aaaaaactgg atgagaattt actgacatgc
     7861 tattttatgg caattgcata tggtgatttt tcaaagttaa attatgttga tatatatgga
     7921 attgaatcaa cttttgttaa taaaacagta gtagaaaaga ttcataaaat gaacaaaaaa
     7981 atcttcgttt ggactgttaa tagtgacagt ttaattgaga aaatgcttga cctaaatgta
     8041 gatagtatta ttacagataa tccatacctt atagagagtg caatttattg gaagaaaaat
     8101 ggatttatta gtcaagtgtc agattattta ttttaaatat tctataattg tattatccag
     8161 taaaagagat attattaaaa tcaataatat ctctttttaa cataaataag gttgttaaat
     8221 taaggctatt cttataaaaa ttgtgtttat cagatataaa taaggaataa aagtaaaaaa
     8281 attgctatga cattattaca attaaaagag ttttaatatg atagagaggt agattgtcaa
     8341 ctgtatattt aataaatttt attatttatt agattttata taagtaaaat atatagatat
     8401 ataaatctta tgctagaata tatatgaaaa acaatataga tttggagggt taaaagcatg
     8461 acagagcgag aaaaaatgtt ggcaggagaa ctttacgatt gtggtgatat tgagttgtta
     8521 actcaatggc ataaagcaaa agacctagta agagattata accaaacaga ttccttggat
     8581 ttggaaaaaa aagaaaaaat attaaatgag ttacttggtg gtaagggtaa aaacttatgg
     8641 attactgcac cgtattatgt agattatgga aataatattt attttggaaa taattgtgaa
     8701 gtcaatatga attgtacgtt tttagatgat aataaaatta tcattgggga taatgcacta
     8761 atcgcaccaa acgtacaaat atatactgca tttcatccaa ctaatgctgg tgatagattt
     8821 ggtaatgcca aagaagatgg ttcatttgaa ttttgtaaaa ctcaaacagc tccagttact
     8881 attggagata atgtttggat tggcgggggt gctattatca tgccaggtgt tactattgga
     8941 gataatgtag ttataggtgc aggaagtatt gttacaaaag atattccaag taatatgatt
     9001 gcatacggaa atccatgccg tattattcga gaaaataaat aaagttaaat tttcttgcaa
     9061 aatctcaaaa aacacctttc ttactttata catagggtat tttctaatac tttcacatcc
     9121 atattcattt gttaaatttt tgtggaatgt agtttttatc acttctatct tacatttcca
     9181 ccattttttt ataaaagtca ttcctttata gatttattta taatagtata tattctattt
     9241 gatgtttgaa taagcactta tttttaagta aaatactaac ttctaggtta gtattttact
     9301 atagtatgat gattaagtaa gaataaaata ctataataca ta
//
LOCUS       DAMJVG010000116         8996 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.121, whole genome shotgun sequence.
ACCESSION   DAMJVG010000116 DAMJVG010000000
VERSION     DAMJVG010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8996)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8996)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8996
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.121"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            95..661
                     /locus_tag="PC512_003387"
     CDS             95..661
                     /locus_tag="PC512_003387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HDF2443103.1"
                     /translation="MRKLEEILEYNKSFVENKEYEQYVTSKHPNKKIVVLSCMDTRLT
                     ELLPKAMNLKNGDVKLIKNAGATIMHPFGSIMRSVLVAIYEFDVDEVMVVGHHGCGMC
                     NVDTDKLLGKILDRGISNDVILTLRSAGIDTKQWLHGFDSAEESVKDSIDLIKGHPLI
                     PDGIIVHGLIISPETGKLDVVVNGYEDK"
     gene            966..1427
                     /locus_tag="PC512_003388"
     CDS             966..1427
                     /locus_tag="PC512_003388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2443104.1"
                     /translation="MNSNSEEKLNDVFLQLMRIYFIRTHFYFDKLGLYHGQPQILFSL
                     KMKDGQSQKELADKRKVKASTTTVMIKRMEKAGLVERKQDEKDQRVSRIFLTDKGLEI
                     CNKVEEFNKELEREFFLGFSEEEKIVLRRLLMQVRDNLKAGCHKHEDEKYF"
     gene            1495..3741
                     /locus_tag="PC512_003389"
     CDS             1495..3741
                     /locus_tag="PC512_003389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011009877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2443105.1"
                     /translation="MFKLIKYLKKSALSIVIIVCLLVIQAVCDLSLPEYTSNIVNVGI
                     QQGGVENSVPSVIRESELNKITLFMDKSSKDKVLDNYTLLNKKDYVKYKDKYPGLKDE
                     SLYELNTKDKDTIDDLNVIFGKAILIVSGLEGDSKEVKAMKAQLMSKLPPQATQSGDV
                     DIFKLLSAMPKEQLDTLTKEMSKGFESMPESMITQSSVSYVRSEYEKIGIDTEKTQNN
                     YILFTGAKMLGIAMISMVATITVGFLAARVAASVGRNLRSGVFRKVMSFSNTEMNEFS
                     TASLITRSTNDIQQIQMLMVMLLRIVFYAPIMAIGGVIKVLNTNTSMAWIIAVAVVAI
                     LSLIVVLFSVVMPKFKLVQKLVDKLNLVSREIITGIPVIRAFSTEKHEEERFDKANKN
                     LTKTNLFVNRVMTCMMPAMMLIMNLITVLIVWRGAYSVDSGAMQVGDMMAFIQYTMQI
                     IMSFLMISMVSIMLPRASVSATRIDEVLVSDISIKDPEKSEAQEFKEDKKGLVEFKNV
                     SFMYPDAEEPILTNISFTAKPGETTAFIGSTGSGKSTLINLIPRFFDVTEGEILLGGV
                     NIKNVSQHDLREKIGYVPQKGVLFSGTIESNLKYGRKDATDEEMRTAAEIAQATEFID
                     SKPEAFKTEISQGGTNVSGGQKQRLSIARAIAKNPEVYIFDDSFSALDLKTDAALRKA
                     LKSKTAESTVLIVAQRISTILNAEQIIVLNEGEIVGIGTHKELLKNCEVYEQIALSQL
                     SKEELANE"
     gene            3734..5566
                     /locus_tag="PC512_003390"
     CDS             3734..5566
                     /locus_tag="PC512_003390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2443106.1"
                     /translation="MSRMGRGPMGKSMGAGQKANDFKGTMRKLIAYLSKFKISIILVI
                     VFAIGSASFSIVGPKILGKATTKIFEGLVSKVSGGNVGIDFNAIGKILTFLLFLYLIS
                     ALFSFIQGFIMSGISQKVSYNLRKEISAKLDRLPMKYFDTKTHGEILSRITNDIDTLN
                     QSLNQSMTQLITSVTTMIGVLIMMLSISGIMTLVAVLILPISMFVISRIIKKSQKYFR
                     YQQEYLGNVNGQVEETYSGQTIVKAFNREDEVIEEFDKLNDSLYNSAWKSQFLSGIMQ
                     PLMMFIGNLGYVMVSILGGWLAIKKTIEVGDIQSFIQYVRNFTQPMTQIAQVANLLQS
                     TAAASERVFEFLEEEEEVQIVENAVSIDGLEGKIDFENVNFGYNPNKTIINDFSVNVE
                     PGQKVAIVGPTGAGKTTIVKLLMRFYDVNSGSILIDGHNIKDFNRSELREMFGMVLQD
                     TWLFSGSIMENIRYGKLNATDEEVIEAAKSAHVHRFIKTLPDGYKMKLNEEASNVSQG
                     QKQLLTIARAILADPKILILDEATSSVDTRTEVLIQKAMDNLMEGRTSFVIAHRLSTI
                     RDADMILVMNEGDIVEQGNHEELLKKGGFYANLYNSQFEEDEAM"
     gene            6285..7562
                     /gene="hflX"
                     /locus_tag="PC512_003391"
     CDS             6285..7562
                     /gene="hflX"
                     /locus_tag="PC512_003391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HDF2443107.1"
                     /translation="MDMAKKGITVGLNINNKSEDFNELMIELENLCSACDIDVVGSIT
                     QNAKQVNRAFYIGTGKVEEILNLIKKENIEIVIFYNELSTSQLKNLEEKLNCEIIDRT
                     ALILDIFAQRAKTREAKLQVEVASLKYMLPRLIGSNENLGRQSGGVGTKNRGSGEKKL
                     ELDRRRIEEKITSLNRELDDLKFQRETQRSMRRKSNLPNVALVGYTNAGKSSIMNKLV
                     DIFKNSEEKKVFEKNMLFATLETSVRNIVLANNKEFLLSDTVGFVSNLPHDLVKAFRS
                     TLEEACEADVLLHVIDISNPSYKSHIKVTEDTLKQIGADGIPMIHVYNKIDLIDVDVL
                     DRILDSIDKEGIFVSVKKDINIDKMIKCICDSIFKDYVRCKFLIPYDKGHVVSYFNEN
                     MSIINTEYREDGAILDVECSNIEYNKYKKYALE"
     gene            7795..8292
                     /locus_tag="PC512_003392"
     CDS             7795..8292
                     /locus_tag="PC512_003392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2443108.1"
                     /translation="MDAETLMKKYMVDDDSRKQAIFASIFVMQNKLQTTCDKLDPELT
                     MKQWLLLAIADSVDETLTLTKLGELMGCSRQNVKKLAIALEKKGFIQIEQNEKDSRAI
                     CLVTKDRVQEYSKKVRGMQEKVLQLLFEDFTEKEVEQLFFGIMKLSIGIENVKNYVEN
                     NDVGE"
     gene            8342..8866
                     /locus_tag="PC512_003393"
     CDS             8342..8866
                     /locus_tag="PC512_003393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HDF2443109.1"
                     /translation="MKNVVVIYKSKYGSTKKYAKWLSELLSCDIFETKNINIEKVMKY
                     DTIILGGGLYACNIAGISFLKKNYKELQKKNLVVFGVGAAPYDDEVIKKLREVNFKDE
                     LNKIPCFYCRGAWDETKMSFIDYTLCSFFKKSIAKKERQGLKPAEAPLLSGEAFDWCN
                     KENLTPILDYIREL"
BASE COUNT         3566 a          901 c         1627 g         2902 t
ORIGIN      
        1 aatttaataa atataaatta aattatatgt gtatatattg tactttaata gtgatataat
       61 aataaaaaaa tttttaaaga gggtgatatt acatatgaga aaacttgaag agatattaga
      121 atataataaa tcatttgtag agaacaaaga atatgaacaa tatgtgacat caaaacatcc
      181 aaataaaaaa atagtagtct tatcttgtat ggatacaaga ttaactgagc ttttgcctaa
      241 ggctatgaat ttgaaaaatg gagatgtgaa actaataaaa aatgcaggag ctactataat
      301 gcatcctttt ggaagtatta tgagaagtgt tttagttgca atttacgaat ttgatgtaga
      361 tgaggttatg gttgtagggc atcatggatg tggtatgtgt aatgttgata cggataagtt
      421 acttggtaaa attttagata gaggaatatc taatgatgta atacttacac ttcgtagtgc
      481 tggaattgat acaaaacaat ggttacatgg attcgattct gcagaagaat ctgtaaaaga
      541 tagtattgat ttaataaaag ggcatccttt aattccagat ggtattattg tacatggtct
      601 aattatatca cctgaaactg ggaagttaga tgttgttgta aatggatatg aagataagta
      661 gagtatcata atgttatata atcaagatac tgttgaataa gatgttgttt caaaatttat
      721 tttgggacaa cttttttatt tgaaaatata tgaaaaggtt tattttaagc tttacaataa
      781 aaaatataag tagctgacta attaaaaatc ttactattat ttattaaaat tataactata
      841 tgatataaaa atatttaata aatgaaattt atatgaattt tttataaata tattgaaaaa
      901 atgcatgcag tatagtaaaa taatgcttag ccgactaagt aatataaaaa ataaggaggg
      961 caagtatgaa tagcaattct gaagaaaaat taaatgatgt tttcttgcaa ttaatgcgaa
     1021 tatattttat aagaactcat ttttattttg ataaattagg cttatatcat ggtcaacccc
     1081 aaatactttt ttctttaaag atgaaagatg ggcaaagtca aaaagaatta gcagataaaa
     1141 ggaaagtaaa agcatctaca actacagtta tgataaagag gatggaaaaa gctggacttg
     1201 tggaaagaaa acaagatgaa aaggaccaaa gagtatctag gatttttttg acagacaaag
     1261 gtttagaaat atgtaataaa gttgaagaat ttaacaagga attggaaaga gagttttttt
     1321 taggatttag tgaagaagaa aaaatagtac ttagaagact tctaatgcaa gtacgagata
     1381 atttaaaagc aggatgtcat aagcatgaag atgaaaaata tttttaaagt ttaaaataat
     1441 gtttttcaat ttaatgttat tagactaatt aatattacag aagggaagaa atgtatgttt
     1501 aaattaatta aatatttaaa gaaatcggca ttatcaatag taataatagt ctgtctattg
     1561 gtaattcaag cggtatgtga cctttcttta ccagaataca catccaatat agtaaatgta
     1621 ggtatacaac aaggtggagt agaaaactct gttccatctg tgattagaga gagtgaatta
     1681 aataaaatta ctttatttat ggataaaagt agtaaggata aagtactaga taattatact
     1741 ttgctgaata aaaaggatta tgttaagtat aaagataagt acccaggtct aaaagatgaa
     1801 tctctttatg agttaaatac taaagacaaa gacactatag atgatttaaa tgttattttt
     1861 ggtaaagcta ttttaatagt atcagggctt gagggcgata gtaaagaggt aaaagctatg
     1921 aaagctcagt taatgagtaa acttccacca caagctactc aaagtggaga tgttgatata
     1981 tttaaattgt tatcagcaat gccaaaggaa cagttagata cattgactaa agagatgagc
     2041 aaaggctttg aaagtatgcc agagagtatg ataacacaaa gctctgtttc atatgtaagg
     2101 tcagaatatg agaaaatagg tattgataca gaaaaaactc aaaataatta tatattattt
     2161 actggtgcta aaatgcttgg tatagcaatg attagtatgg tagctacaat aacagtagga
     2221 tttttagcag caagagtagc cgcaagtgta ggtagaaatt taagaagtgg agtatttaga
     2281 aaagttatgt cattttcaaa tactgaaatg aatgaatttt ctacagcttc attaattact
     2341 cgtagtacaa atgatattca acagatacaa atgttgatgg ttatgttgct tagaatagta
     2401 ttctatgcac ctataatggc tataggtgga gtgataaagg ttttaaacac aaatacttca
     2461 atggcctgga ttatagcagt agcagtagtt gctatcttat cattaattgt agtgttattc
     2521 tcagtggtta tgcctaagtt taaactggtt caaaagcttg ttgataagtt aaacttagta
     2581 agccgtgaaa taattactgg tattccagtt atcagagctt ttagtactga aaaacatgaa
     2641 gaagaaagat ttgataaagc aaataaaaat ttaactaaaa caaatctttt tgtaaataga
     2701 gttatgacat gtatgatgcc tgctatgatg cttataatga accttatcac agttcttata
     2761 gtttggagag gtgcatacag tgttgattct ggagcaatgc aagttggaga tatgatggca
     2821 tttatacaat atacaatgca aataataatg tcattcttaa tgatatcaat ggtatctatt
     2881 atgcttccaa gagcatccgt ttcagctaca cgtatagatg aagtattagt gtcagatata
     2941 agcataaaag acccagaaaa atcagaggca caagagttta aggaagataa aaagggtctt
     3001 gttgaattta aaaatgtttc gttcatgtat ccagacgcag aagaacctat attaacaaat
     3061 atatctttta cagcaaagcc aggagaaaca actgccttta taggaagtac tggtagtggt
     3121 aagtcaactc ttataaattt aattcctcgt ttctttgatg ttactgaagg agaaatatta
     3181 cttggtggag ttaatataaa aaatgtttct caacatgatt taagggaaaa aattggatat
     3241 gtacctcaaa agggagtatt gttttctggt actatagaat ccaacttaaa atatggtaga
     3301 aaagacgcaa cagatgaaga aatgagaaca gcagctgaaa tagctcaagc tacagaattt
     3361 atagattcta aaccggaagc ttttaaaact gaaatttctc aaggtggaac aaatgtatct
     3421 ggaggtcaaa aacaaagact ttctattgca agagcaatag caaaaaatcc agaagtttat
     3481 atatttgatg atagtttttc agcacttgac ttaaaaactg atgcagctct tcgtaaggct
     3541 ttaaaatcaa aaactgctga aagtacagtt ctaatagttg cacaaagaat tagtactatc
     3601 ttaaatgcag aacagataat tgttttaaat gagggcgaaa tagttggaat aggaacacat
     3661 aaagagcttc taaaaaattg cgaagtttat gagcaaatag ctttatcaca actttcaaag
     3721 gaggagctag ctaatgagta gaatgggaag aggtcctatg ggaaaatcta tgggagcagg
     3781 acaaaaagca aatgacttta aagggactat gcgaaaacta attgcatatt tatctaaatt
     3841 taaaatatca ataattctag taattgtatt tgctattggt agtgcgtcgt tttctatagt
     3901 aggtccaaaa attttaggaa aggcaactac aaagatattt gaagggctag tgagtaaagt
     3961 ttctggagga aacgtaggta tagattttaa tgcaattgga aaaatcttaa cctttttact
     4021 tttcctttat ttgataagtg cactgttctc ttttatacaa ggatttataa tgagtggaat
     4081 ttctcaaaaa gtatcctata atttaagaaa agagatttca gcaaaattgg atagattgcc
     4141 aatgaagtat tttgatacta agacgcatgg tgaaatatta tcgagaatta cgaatgatat
     4201 agatacttta aatcaaagtt taaatcaaag tatgacacag cttataacat cagtaacaac
     4261 tatgataggt gttttgataa tgatgttatc tataagtgga attatgacat tagtggcagt
     4321 tttaatatta ccaatatcaa tgtttgtaat ttcaagaata ataaagaaat cacaaaaata
     4381 ctttagatat caacaagaat atttaggaaa tgtaaatggt caagttgagg aaacttacag
     4441 tggccaaaca atagtaaaag catttaatcg tgaggatgaa gtaattgaag agtttgataa
     4501 actaaatgat agcctgtata attcagcgtg gaaatctcaa tttttatcag gtataatgca
     4561 accacttatg atgtttattg gaaacttggg atatgtaatg gtatcaatct taggaggttg
     4621 gcttgcaatt aagaaaacaa ttgaggttgg tgacatacag tcatttatac aatatgtaag
     4681 aaactttaca cagccaatga ctcagattgc acaggttgcc aatttattgc aatcaacagc
     4741 agcagcttct gaaagagtat ttgagttttt agaagaggaa gaagaagtcc aaattgttga
     4801 aaatgcagtt tcaatagatg gtttagaagg taaaattgat tttgaaaatg tcaactttgg
     4861 atataaccca aacaagacta taataaatga tttctcagta aatgttgaac ctggtcaaaa
     4921 agttgctatt gttggaccta caggagcagg taaaactaca atagttaaac tgttaatgag
     4981 attttatgat gttaatagcg gttcaatact gattgatggt cataatatta aagattttaa
     5041 tcgtagtgag cttagagaaa tgtttggtat ggttcttcaa gatacatggt tatttagtgg
     5101 ttcaattatg gaaaatataa gatatggtaa gttgaatgct acagatgaag aagttataga
     5161 ggctgctaaa tctgcacatg ttcatagatt tattaagaca ttaccagatg gatataagat
     5221 gaaattaaat gaagaagcaa gtaatgtttc tcaaggtcaa aaacaattat tgactatagc
     5281 tcgtgctatt ttagctgatc ctaaaatttt aatattagat gaagctacaa gttctgtcga
     5341 tactagaaca gaagtattga ttcaaaaagc tatggataat cttatggaag gtagaacaag
     5401 ttttgttata gcccacagat tatcaactat acgtgatgct gatatgattc ttgtaatgaa
     5461 tgaaggagat atagttgaac aaggaaatca tgaggaactt ctaaagaaag gcggattcta
     5521 tgccaatctt tacaattctc aatttgaaga agatgaagca atgtaacaaa aaactatctt
     5581 agcatagaca tgtaattaat aagataaaat aaatgagggt gccttaaaat gaacttttta
     5641 attcataagg cactcttttg tgtatgaaat aaagtgtatt tttatcattt taacaatgaa
     5701 aaagaggatt ctctatattt tgagatagcc acataatttt atgtctttac aaagtgttta
     5761 ttttattata atatgtagta aggaaaatgt tggaggtgat tatcaaaatg tatatttaat
     5821 tttattcttt aaattttatt ataaatagaa tttaatttta atagttgatg attatattga
     5881 agtatatgtt tttattactt ttattaatca tgcaaataac tacttaaatt taagaatagg
     5941 gttaaatata aaatgataat tacatataag ttaattaaac taatgtattt ttaatatata
     6001 tttagaattt taatccttct tatgatataa gtagcttgtt ttgtattact tagatttgta
     6061 aggagttttt ttattgaaaa aactgcataa tatatttggg aggaggtgta agaaagtgat
     6121 tttttatata agattgagaa aataatgcac gattatggtt attataatag taaataagaa
     6181 gtgtcattta aggataagat aaaaagcaaa atttttgatg aatttaatta tagagccata
     6241 atctcgtgct atagattaaa taaaaaatag cagataagga gaatatggat atggcgaaaa
     6301 aaggaataac agtaggatta aacataaata ataaatctga ggactttaat gaactaatga
     6361 ttgaacttga aaacttatgt tcagcatgtg atattgatgt tgtagggagt ataactcaaa
     6421 atgcaaagca ggttaataga gcattttaca ttgggacagg taaagttgag gaaatattaa
     6481 acttaataaa gaaagaaaat atagagatag ttatatttta caatgaactt tctacatcac
     6541 aactaaaaaa tcttgaagaa aagcttaatt gtgaaattat agatagaacg gcattgatac
     6601 ttgatatatt tgcacaaagg gcaaaaacta gagaagctaa acttcaagta gaagtagcaa
     6661 gtttaaaata tatgttacca agacttatag gttcaaatga aaatttagga cgtcaaagtg
     6721 gtggagttgg tactaaaaat agaggttctg gtgagaaaaa attagaactt gaccgtagaa
     6781 gaatagaaga aaagataaca tctttaaata gggagttgga tgatttaaaa ttccaaagag
     6841 aaactcaaag aagtatgaga agaaaatcaa atcttccaaa tgtagctcta gtcgggtata
     6901 caaatgctgg taaatcttca ataatgaata aactagtaga tatatttaaa aactctgaag
     6961 aaaagaaagt gtttgagaaa aacatgttat ttgctacact tgaaacttct gtcagaaata
     7021 tagttcttgc aaataacaaa gaatttttat tatctgatac tgttggtttt gtaagtaatc
     7081 taccacatga cttagtaaaa gcatttaggt caacattaga agaagcatgt gaggcagacg
     7141 tactgttaca tgttattgat atttcaaatc caagctataa aagtcatatt aaagtgacag
     7201 aagatacttt aaaacaaata ggtgcagatg gtatacctat gatacatgtg tataataaaa
     7261 ttgatttaat agatgtagac gtattggata gaattttaga tagtattgat aaagaaggta
     7321 tatttgtttc agttaaaaaa gatataaata tagataaaat gataaaatgt atttgtgata
     7381 gcatatttaa agattatgta agatgtaagt tcttaattcc atatgataaa ggtcatgtag
     7441 tttcttattt taacgaaaat atgagcatta taaatacaga atacagagaa gatggagcta
     7501 ttttagatgt agaatgtagc aatatagaat ataataagta taaaaagtat gctttagagt
     7561 aaattttgaa aaacttatta tagcctaaaa tatatttaat ttataattta ttataaattg
     7621 attgtaaata tgattttatg aaacggtata gccataatgc tatgccgttt tgccatttat
     7681 aataaaaata aatttattga cataatagta actaattact ataatataaa gtaattagtt
     7741 actatttaaa attatcaaaa aattaaaatc taagataaag agaagtgtat aataatggat
     7801 gcagaaactt taatgaaaaa atatatggta gatgatgata gtagaaaaca agctatattt
     7861 gcaagtatat ttgtaatgca aaataaactt caaactacat gtgataaatt agacccagaa
     7921 ttaacaatga aacaatggtt acttttagct attgcggact ctgtagatga aactcttaca
     7981 ttaaccaaac ttggagaatt aatggggtgc tcaagacaaa atgtaaaaaa actagctatt
     8041 gctttagaaa agaaaggttt tatacaaatt gagcagaatg aaaaagattc aagagctatc
     8101 tgtcttgtga caaaagatag agtgcaagag tattctaaaa aagtaagagg tatgcaggaa
     8161 aaagtattac agcttttatt tgaagatttt acagagaaag aagtggaaca gttatttttt
     8221 ggaattatga aattaagtat aggaattgaa aatgtgaaaa attatgtaga aaataatgac
     8281 gttggagaat aagcaagtat caaatcaact ttgtatgaca tcagagaggg ggataattta
     8341 tatgaaaaat gtagtagtga tttataagag taagtatggt tcaacaaaaa aatatgctaa
     8401 atggctttca gaattattgt cttgtgatat ttttgaaact aagaatatta atatagaaaa
     8461 ggttatgaag tatgatacga ttattttagg aggaggtctt tatgcttgta atatagcggg
     8521 aatttctttc ttaaaaaaaa attataaaga attgcagaaa aaaaatttag tagtatttgg
     8581 cgtaggagct gctccatatg atgatgaagt aataaagaaa ttaagagaag taaattttaa
     8641 ggatgaatta aacaaaattc cttgctttta ttgtcgtggg gcatgggatg agacaaaaat
     8701 gtcttttata gattatactc tttgtagttt ttttaaaaaa tctatagcta aaaaagaacg
     8761 tcaaggtctt aaaccagcag aagcaccttt attgtctgga gaagcatttg attggtgtaa
     8821 taaagaaaat ttaactccaa tacttgatta tataagagaa ctttaagagg tatatattta
     8881 taattattta ttatctaaag ttagatttca tagaaactta ctagacatta tttataaaat
     8941 aatattatta aagatggata atttaattga ttcaataagg ttataatttt aaaaaa
//
LOCUS       DAMJVG010000117         8899 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.122, whole genome shotgun sequence.
ACCESSION   DAMJVG010000117 DAMJVG010000000
VERSION     DAMJVG010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8899)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8899)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8899
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.122"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(333..1229)
                     /locus_tag="PC512_003394"
     CDS             complement(333..1229)
                     /locus_tag="PC512_003394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF2443110.1"
                     /translation="MKDKNTYFNRKGQENFIDIFLKDDIKKGANFKRHWHEHLQIYYF
                     IDGIAYLECGLDNFKVVPGNIVIANSNELHYLESLSDNLKFYSIRIEPTFLFSNQVDL
                     LQTKYLAPLALNHIVFNNLIQNDSLILKCITTILDEYHNKEVGYELSIKANIYQLIVL
                     LLRSHIDKIYSEDEFIKRKYSLEKFECIFDLIEEKYMDKITLKELASRVNLSAHHFCR
                     TFKQITGKTTIDFINGIRLDKAIYYLKETDLNMTEIAMRCGFDSINYFSRLFKKNYNI
                     SPTKYRNEHREVSNVILKEDMK"
     gene            1370..2797
                     /locus_tag="PC512_003395"
     CDS             1370..2797
                     /locus_tag="PC512_003395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2443111.1"
                     /translation="MTNSFKKDDNRKKITVLFVVIAMTFMATLDSSIINVALPVLASK
                     LNVSLASIEWVIASYSIIICSTLLFFGRLGDIIAKSRVFQVGTILFTSASLLCGLSNS
                     LTLLIVCRFIQGIGASAYMANNHGIITELFPKESRGKALGILVTAVAIGNMVGPSVGG
                     FILSIFNWNVIFFINIPIGLIVIFLNTKFLPNSKKSSENMDKTGAILQFLGTTLFFSA
                     LISAQQTGLLNPYILIALLLSIIFIILFLILEKKHPQPLLDLEIFRNFKFSLNLICAL
                     TSFICIASSSILIPFYLQSTMKLPPIQAGLFMILSPLILAIFSPIFGNISDKIKSEKI
                     ILIGLLVMSFGFFLMSRLKESSALILFVIYISIISIGQAIFQPANNALIMSSCSRSKL
                     GVVGSINSLVRNLGQVIGITISTTLLYNFMSIKAGYRVNDYVINNDKIFVFGMRNVYI
                     IVTLVCLIGAILIGFYLFKYNKNEQ"
     gene            complement(2993..5587)
                     /gene="clpB"
                     /locus_tag="PC512_003396"
     CDS             complement(2993..5587)
                     /gene="clpB"
                     /locus_tag="PC512_003396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HDF2443112.1"
                     /translation="MDVEKMTLRVQKSLNEAYNEAVKNHNQQVDVIHLFSALINQEDG
                     LIPNIIEKMNISIDSLRNTVNFEIDKLPKVYGEGADSQGVSATRKINEVLIKAESISK
                     EFKDSYISVEHVMLAMMETESKSAVGKILKQYNINKNDFLNILSQVRGSQRVETQDPE
                     GTYDALARYGTNLVDLAKKNKLDPVIGRDEEIRRIIRILSRRTKNNPVLIGEPGVGKT
                     AIVEGLAERIVRGDVPEGLKDKIVFSLDMGALIAGAKYRGEFEERLKAVLKEVQSSDG
                     KIILFIDEIHTIVGAGKTEGSMDAGNLIKPMLARGELNCIGATTFDEYRKYIEKDKAL
                     ERRFQPVIAEEPTVEDTISILRGLKERFEIHHGVRIHDNAIVAAAKLSHRYIQDRFLP
                     DKAIDLIDEAGAMIRSEIDSLPTELDVVRRKLFTLETEREALLKENDDKSKSRLDDIQ
                     KEIAELKSKNDEMTAKYEKEKSQILDIKNLKAQLDEAKGKAEKYEREYDFNKAAEVKY
                     GEIPKLEEQIKQYEENMNDGSENSLLKEEVTEEEISSIVSKWTGIPVTKLVEGEREKL
                     LKLEDELHKRVIGQDEAVTAVSNAVIRARAGLKDERKPIGSFIFLGPTGVGKTELAKT
                     LARNLFDSEDNIIRIDMSEYMEKHAVSRLVGPPPGYVGYEEGGQLTEAVRRAPYSVIL
                     FDEIEKAHEDVFNMFLQILDDGRLTDNKGKTVDFKNTLIIMTSNIGSNYLLEAGGNIT
                     ETTNNLVMNEMKHRFKPEFLNRVDDIIMFKPLDQENIKKIIDIFMKDLKNRLKEKDIT
                     IEVTNSAKDVMVREGYDPVYGARPLKRYIGNTLETIIAKKLIAGDVYNGCTIVIDGKD
                     ENIEVLVK"
     gene            complement(5624..6220)
                     /locus_tag="PC512_003397"
     CDS             complement(5624..6220)
                     /locus_tag="PC512_003397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443113.1"
                     /translation="MSLKLDRNVLQWFDYVFENEKTSLRHYNFNCTLKEISSTSLNKV
                     AFILEKNNSKYWKLYFEIPAEVTLKLKQNIHPLFREYIYEQISLYNNNQIYNFVNSNI
                     LKVFNNIAIYQYNILENLYTIDFKKSFIDKCQYLLIGEKRLIDEDLYLIAKSKEVFDF
                     FNSDGTFNLTLSFDIQKNENLLDSLLELRKSIIINERI"
     gene            complement(6237..6641)
                     /locus_tag="PC512_003398"
     CDS             complement(6237..6641)
                     /locus_tag="PC512_003398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication/maintenance protein RepL"
                     /protein_id="HDF2443114.1"
                     /translation="MDKTLKKDLNQEYTESKSLVMNKSKYMNVCFKNYIKVVEGMYTK
                     RDLIPLKLINSMDKNNKIRKTLYELSCEFEYPKTSLSSLFTELKKMDFLQRVKNGEYM
                     INPHIAYKGSRADKESLLAEYNQIKRPNKVSK"
     gene            7008..7382
                     /locus_tag="PC512_003399"
     CDS             7008..7382
                     /locus_tag="PC512_003399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2443115.1"
                     /translation="MNIVISNSSGKPIYEQITTQIKSMIISGELPEGSALPSMRLLAK
                     ELRISVITTKRAYSDLERDGFIETVTGKGSFVSSKNMDFVKEEQFRLIEEYLQKAVDT
                     AKSSDITYDELKDILFLLYKGE"
     gene            7379..8242
                     /locus_tag="PC512_003400"
     CDS             7379..8242
                     /locus_tag="PC512_003400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2443116.1"
                     /translation="MISMDAITIKNLNKTYKDFSLQDISFSVPKGSVMGFVGENGAGK
                     TTTLKAILNLISYDSGNIEIFGLDSKKNEKEIKEQIGVVFEGSNFHENLNTDHVSKIM
                     SKIYKNWNDTLFKDYLKKLRVPDNKLIKEFSKGNKMKLSIAVALSHKPKLLILDEATS
                     SLDPIVREEILDIFLDFIQDEEHSIILSSHITSDLDKIADYITFIHKGKIVFSENKDE
                     LIDTMGVLKCKPSDFDNLSREDYSYYRKSQFGYEVLLKDKHRFISRHPNCIVDNTSIE
                     EIMLFYVRGDK"
     gene            8242..8880
                     /locus_tag="PC512_003401"
     CDS             8242..8880
                     /locus_tag="PC512_003401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HDF2443117.1"
                     /translation="MKGLILKDLLNLKGNIKFILLFIIMFGFMSSLGDGNVNNFIGVI
                     IVLCTTMIVSTFSYDDLNKWDSYVLTMPINRNDIVLSKYLTMLIFSFIGVLVSLIVSV
                     TIGYFKNTLILNETLLINALILSISVCFGSLILPLIYKFGTERARLLMILCFLVPTLA
                     LLVFKSILENISSPISIEIILNTLVYSLPFVAILLFVISYFISSKIYSKKEV"
BASE COUNT         2983 a         1313 c         1021 g         3582 t
ORIGIN      
        1 gatttaaatt ttctataaaa atcatactat tttagctgtt tacttgctta tttaatagtt
       61 ttatttcttt gattaaatat ctttcagaat ctaagccaga tgtctcaaaa aaactgattt
      121 ataatataat cattttttct gctattctta tttttccaat tttagtttca tattaaaata
      181 tacttttcat agacactaca ttctttcata ctcattttca catttaacta tacaagtagt
      241 cttactcatt tatatcctat gctttattaa tatttattaa gaaaaattca aagatttaaa
      301 aatatatatt ttctataaag tatatttatg aattatttca tatcttcttt taaaataaca
      361 ttactaactt ctctatgttc atttctatac ttagttggag atatattata attcttttta
      421 aataagcgac taaaataatt tatgctatca aagccacatc tcatagcaat ttctgtcata
      481 tttaaatctg tttcctttaa ataatatata gctttatcaa gcctgattcc atttataaaa
      541 tcgattgtag tcttacctgt tatttgctta aatgttctac aaaagtgatg tgcactcaag
      601 ttcacacgac tagcaagttc ttttaatgta attttatcca tatatttttc ttctatcaaa
      661 tcaaagatac attcaaattt ttctaaagaa tactttcttt ttataaattc atcttcagaa
      721 tatattttat caatatgact tcttaataag agtactatta attgatagat attagctttt
      781 atagataact catatccaac ttctttattg tgatattcat caagtatagt tgtaatacat
      841 tttaaaatca gagaatcatt ttgaattaaa ttattaaata caatatgatt taaagccaat
      901 ggtgctaagt acttggtttg taacaaatca acttgattac taaaaaggaa tgtgggttca
      961 atacgaatac tatagaattt taaattatct gataagcttt ctaaataatg taattcatta
     1021 ctgtttgcta ttacaatatt tccaggcact accttaaaat tatccaatcc acattcaaga
     1081 tatgctatac catcaataaa ataatatatt tgtagatgct catgccaatg tcttttaaag
     1141 tttgctcctt ttttaatgtc atcctttaaa aaaatatcta taaagttttc ttgacctttc
     1201 ctgttaaaat atgtattttt atccttcatt attcccccct catcaaaata gtgctaatta
     1261 taagcaatat agttattgta ttcattattt catatcgcta ttatataaaa tgtaactatc
     1321 attgtaaaca ttaacataat gcagtcatta taataaggag gtaataaaaa tgacaaactc
     1381 ttttaaaaaa gatgataata gaaaaaaaat cacagtttta tttgtagtca ttgccatgac
     1441 ttttatggca acattagatt ctagtattat aaatgttgct ctcccagttc ttgcaagcaa
     1501 actaaatgta tctctagcat ctattgaatg ggtaatagca agttactcaa ttattatttg
     1561 ttcaacacta ttattttttg gaagacttgg agatattatt gctaaatcaa gagtatttca
     1621 agtaggtact attctcttta catcagcttc attactatgt ggattaagta attctttaac
     1681 tttacttata gtttgccgct ttattcaagg aataggcgct tctgcctaca tggcaaacaa
     1741 tcatggaatt atcacagaac tatttccaaa agaaagcaga ggaaaagccc tagggatttt
     1801 agttactgca gttgctattg gaaatatggt tggaccatct gtgggaggat ttattttgtc
     1861 aatatttaat tggaatgtta tattttttat aaatattcca atcggtctta ttgtaatctt
     1921 tttaaataca aaatttcttc ctaatagtaa aaaatcttca gaaaatatgg ataaaactgg
     1981 tgctatactt caatttttag gaacaacatt attttttagt gctctaatta gtgctcaaca
     2041 aacaggatta ctaaatccat atatattaat tgcactatta ttatcaatta tttttattat
     2101 attatttttg atattagaaa aaaaacatcc tcaaccgctt cttgaccttg aaatttttag
     2161 aaattttaaa ttttcattga atttaatttg tgctcttaca tcattcattt gtattgcatc
     2221 atcaagtatt ttaattccat tttatttaca aagtactatg aaacttcccc ctattcaagc
     2281 aggtttattt atgatactat cacctttgat tttagccatt ttttcaccta tatttgggaa
     2341 tatatcagat aaaattaagt cagaaaaaat tattttaatt ggtcttctcg ttatgagttt
     2401 tggattcttt ctaatgtcaa gattgaaaga aagttctgcc cttattttat ttgtaattta
     2461 tatatcgata atatcaatag gacaagctat atttcaacct gctaacaatg ctttgataat
     2521 gtcaagctgt tctagaagta agctaggagt tgtaggaagc ataaattccc ttgtaagaaa
     2581 tttaggacaa gttataggta ttactatttc tacaacactt ttatataatt ttatgagtat
     2641 taaagctgga tatagggtca atgattatgt gattaataat gataaaatat ttgtatttgg
     2701 aatgagaaat gtttatatta ttgttacact tgtttgctta ataggtgcaa tattaattgg
     2761 cttttattta tttaaatata ataaaaatga acaatagttt ttataattat attcaaatta
     2821 tgattatatt ataagaaatt tactaaaata cttcctttga gttaaattta atttggacat
     2881 attgacttaa aaatgtttta ttaatttgat aaaatatttc ttttcctata gtttataaat
     2941 aaaaatcagc tgagcaaaat atttagtata ttatgctcaa ctgattcttt tattatttaa
     3001 ctaaaacttc aatattttca tcttttccat ctataactat agtacatcca ttatacacat
     3061 ctccagcaat aagtttcttt gcaattatag tttctaatgt atttcctata tatctcttaa
     3121 gaggtcttgc tccatataca gggtcatatc cttctctcac cataacatct tttgctgaat
     3181 ttgtaacttc aatagtaata tctttttctt ttaatctatt ttttaaatct ttcataaata
     3241 tatctataat tttcttgata ttttcttggt ctaaaggctt aaacattata atatcatcta
     3301 ctctgtttaa aaactcaggt ttaaatctat gcttcatttc attcattact aaattgttag
     3361 tagtctctgt tatatttcct cctgcttcta atagataatt acttcctata ttagaagtca
     3421 ttattataag agtattttta aagtctactg tcttaccttt attatcagta agtctaccat
     3481 catctaatat ctgtaagaac atgttaaata catcctcatg tgctttttct atctcatcaa
     3541 atagtattac agaataagga gcacgtctaa ctgcttctgt aagttgacca ccctcttcat
     3601 atcccacgta ccctggagga ggtccaacta gtcttgatac agcatgtttt tccatgtatt
     3661 cagacatatc tattcttatt atattatctt cactatcgaa taaatttcta gcaagagttt
     3721 ttgcaagttc agttttacca acacctgtag ggcctaagaa aataaatgaa ccaattggtt
     3781 ttctttcatc ttttaatcct gctcttgcac gtattactgc atttgaaact gctgtaactg
     3841 cttcatcttg tccaataact cttttatgaa gttcatcttc tagtttaagt aatttttctc
     3901 tttctccttc aactagttta gttactggta tacctgtcca ctttgataca atgctagata
     3961 tttcttcttc agtaacttct tcttttaaaa gagaattttc agaaccatca ttcatatttt
     4021 cttcgtactg ctttatttgt tcttctaact taggtatttc accatattta acctctgctg
     4081 ctttgttgaa atcatattct ctttcatact tttcagcttt acctttagct tcgtctaatt
     4141 gagcctttaa gtttttaata tctaatattt gactcttttc tttttcatat tttgctgtca
     4201 tttcatcatt tttagatttt aactctgcta tttctttttg aatatcatcc aatcttgatt
     4261 tacttttatc atcattttct ttaagtaatg cttctctttc agtttctaat gtaaataact
     4321 ttcttctaac aacatctaat tctgttggca atgaatctat ttcactacga atcatagctc
     4381 cagcttcatc aattaaatca attgctttat ctggtaaaaa tctatcttgt atatatctat
     4441 gagaaagttt tgctgctgct acaatagcat tatcatgtat tcttactcca tgatgtattt
     4501 caaatctttc ttttaaacct ctaagtatag atattgtatc ttcaacagta ggttcttctg
     4561 caattacagg ctgaaaacgt ctttcaagag ccttatcttt ttctatatac tttctatatt
     4621 catcaaaagt agttgcacca atacagttca attcacctct tgcaagcata ggtttaataa
     4681 gattacctgc atccattgaa ccttctgttt taccagctcc aacaatagta tgaatctcat
     4741 ctataaacag tataattttt ccatcagaac tttgaacttc ttttaaaact gcctttaatc
     4801 tttcttcaaa ttcacctcta tattttgcac cagcaattaa agctcccata tcaagtgaga
     4861 atacaatctt atcttttaaa ccttctggga catctcctct tactattctc tctgctaacc
     4921 cttctacaat tgcagtttta cctacacctg gctcaccaat caatacagga ttattttttg
     4981 ttcttcttga taaaattctt ataatccttc ttatttcttc atctctccca attacagggt
     5041 ctaatttatt tttcttggct aaatctacta agtttgttcc atatctagca agtgcatcat
     5101 atgtgccttc tgggtcttgt gtttctactc tttgactacc tctcacttgt gataaaatat
     5161 ttaaaaagtc attcttattt atattatatt gttttaatat tttaccaaca gctgattttg
     5221 attctgtttc catcattgca agcataacat gttctacact tatatatgaa tctttaaatt
     5281 ctttagaaat actctctgcc tttataagca cctcatttat ttttctagta gctgatactc
     5341 cttgtgagtc agcaccttct ccatatactt ttggaagctt atcaatttca aagtttacag
     5401 tatttctcaa agaatcaatt gatatattca ttttttcgat tatatttggt atcaatccat
     5461 cctcttgatt aataagtgct gagaaaagat gaattacatc tacttgttgg ttatgatttt
     5521 ttactgcttc gttataagcc tcatttaaac ttttttgaac tcttaaagtc attttttcta
     5581 cgtccatata aatccctcca ttttaatatt atatccaaat aaattaaatt ctctcattta
     5641 taattattga ttttctaagc tctaaaagac tatcaagtaa attctcgttt ttttgtatat
     5701 cgaaactcaa tgttaaatta aatgttccat ctgaattaaa aaaatcgaat acttcttttg
     5761 attttgctat taaatacaag tcttcatcta taagtctttt ttcacctatt aataaatact
     5821 gacatttatc tataaaactc tttttaaaat caatagtgta tagattttct aaaatattat
     5881 attgataaat agcaatatta ttaaacactt ttaatatgtt tgaatttaca aaattgtaaa
     5941 tttgattatt gttatacagt gatatttgtt cgtatatata ttccctaaat aaaggatgaa
     6001 tgttttgctt aagttttaaa gtaacttcag ctggtatttc aaaataaagc ttccagtact
     6061 tagagttatt tttttctaaa ataaaagcta ctttgttcaa actggtagaa ctaatctcct
     6121 ttagtgtaca attaaaatta tagtgtctca aactagtttt ttcattctca aatacatagt
     6181 caaaccactg tagaacattt ctatcaagtt ttaaactcat ataaaaacct tcttccttat
     6241 ttactaacct tattaggtct ttttatctga ttatattctg ctaataaact ttctttatca
     6301 gctctactac ctttatatgc tatatgtgga tttatcatat actcaccatt tttcactctt
     6361 tgtaaaaaat ccattttttt cagctccgta aacaatgaag ataaagaagt ttttggatat
     6421 tcaaattcac aagataattc atataatgtt tttctaatct tattattttt atccatagag
     6481 tttattaatt ttaatggaat taaatccctc ttagtataca ttccttctac tactttaata
     6541 taattcttaa aacaaacatt catatactta cttttattca taactaaact tttgctctct
     6601 gtatattcct gatttaaatc cttttttaat gtcttatcca aattaaatat ctcttctcac
     6661 tctccttatc tctaattgat aatataaata tattacaaaa aaatatgtat gtcaaaactg
     6721 aaaatgcaaa aagttcacct tataagtaaa cttttattta gctataagct aaactttatt
     6781 atttttttaa tttagtattt ccaatttatt ggcaggattt ttgaacaata tttataaatt
     6841 ttttaaaaaa atttaaatct atttaatatg gcagactttc ataaaataca ttacatttat
     6901 taaatgtata atattggcaa ttagtttttt ctaaaatcag ttgacatatt atatatatat
     6961 ttatataatg tgtatatact atatatacaa tttaaggagg tgtcttattg aatatagtta
     7021 ttagtaattc gagtgggaag ccaatatatg aacagattac tacacaaatt aaaagtatga
     7081 ttataagtgg agagttacca gaaggctcag ctcttccaag tatgagacta ttggcaaaag
     7141 aacttagaat aagtgtaatt actacaaaac gagcatatag cgatttagaa cgagacggat
     7201 ttattgagac agttactggt aaaggcagtt ttgtatctag taaaaacatg gattttgtca
     7261 aagaagaaca atttcgttta attgaagaat acctacaaaa agcagttgat acagcaaaaa
     7321 gtagtgatat tacatatgac gaattaaaag atattttatt tttattatat aaaggagaat
     7381 gataagtatg gatgcaataa ctataaaaaa tttaaataaa acttataaag attttagcct
     7441 acaagatata tctttttcag taccaaaagg gagtgtaatg ggatttgtag gtgaaaatgg
     7501 tgcaggaaaa acaactacat taaaagcaat tttaaattta atatcttatg atagtggaaa
     7561 tatagaaatc tttggtcttg atagtaaaaa aaatgaaaaa gaaattaaag agcaaattgg
     7621 ggttgtattt gagggaagca actttcatga aaatttaaac actgaccatg tttcaaaaat
     7681 catgagtaaa atctataaaa attggaatga cacattattt aaagactact taaaaaaatt
     7741 gagagtacca gacaataaat taattaagga gttttcaaag gggaataaga tgaaacttag
     7801 tattgctgta gccttatctc ataaaccaaa attattaata ctagatgagg caactagttc
     7861 acttgaccct atcgttcgtg aagaaatact agatatattt ttagatttta tacaagatga
     7921 agaacactct attatcttat cttcacatat tacaagtgat ttagataaga tagcagacta
     7981 tattacattt atacataaag gaaaaattgt atttagtgaa aataaggatg aattaattga
     8041 tactatggga gttttaaaat gtaaacctag tgattttgat aacctttcaa gagaggatta
     8101 ttcatattat cgtaaaagcc aatttggata tgaagtactt cttaaagata agcatagatt
     8161 tatctcaaga catccaaact gtattgttga taatacgtct atagaagaaa ttatgttatt
     8221 ttatgtgaga ggtgataaat aatgaaaggt ctaattttaa aagatttact taatttgaaa
     8281 ggaaatataa agtttatact tttattcatc attatgtttg gctttatgtc ttctttagga
     8341 gatggaaatg ttaataactt tataggtgtt attatagttt tatgtactac aatgattgtt
     8401 tcaacatttt catatgatga tttgaataaa tgggatagtt atgtacttac aatgcctatt
     8461 aatcgcaatg atattgtatt aagtaaatat ttaactatgt taatatttag ctttataggt
     8521 gttcttgttt cacttattgt tagtgtaact attggttatt ttaaaaatac acttatatta
     8581 aatgaaacac tacttattaa tgcactaatc ttatcaattt cagtatgttt tggtagcctt
     8641 attctaccac ttatttataa atttggtaca gaaagagctc gtttattaat gattttatgc
     8701 tttttagttc caacactagc tttattagtt tttaaaagta ttttagaaaa tattagttca
     8761 cctatttcta tagaaattat acttaataca ctagtatatt ctcttccatt tgttgctatt
     8821 ttactatttg tgatttcata ttttatatca tcaaaaatct atagtaaaaa agaagtataa
     8881 aatatactat atatgtttc
//
LOCUS       DAMJVG010000118         8661 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.123, whole genome shotgun sequence.
ACCESSION   DAMJVG010000118 DAMJVG010000000
VERSION     DAMJVG010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8661)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8661)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8661
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.123"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            140..490
                     /locus_tag="PC512_003402"
     CDS             140..490
                     /locus_tag="PC512_003402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HDF2443118.1"
                     /translation="MSAKVTNQYGNIEIDNQVIAQVVYRAAMESYGLVGLAYKSKGIV
                     ELLKGENATKGVRVEEVEEDAIAIELYVIIQYGTNISTVANNIIDRVKYVVEKMTGVR
                     VTRIDINVQGIRVK"
     gene            509..2152
                     /locus_tag="PC512_003403"
     CDS             509..2152
                     /locus_tag="PC512_003403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HDF2443119.1"
                     /translation="MIQYIDGKRLREMFISGANNLQNNKELVDKLNVFPVPDGDTGTN
                     MSLTISYALKELAKVENDNISDIGKALSKGSLMGARGNSGVILSQIIRGIAKSIEGKS
                     KLSTEDLAKAFKNGSDTAYKAVIKPIEGTILTVVRESGEFAIKTAKKEKDVVKFLSML
                     VKESNSSLERTPDLLKNLKEAGVVDSGGKGLVLIYEGMLASIKGDNIEIKNVDLDTNI
                     STSMDFAKSTTSTDDIKYCYCTEFILESSKVEDTKIRDIMMAYGDSLAVVGDDGVIKV
                     HVHTNDPGNVLQEALKYGQLLTIKIENMKLQHENTLLDVEEKKENDSEPLEEEKEFGF
                     IATSMGEGLANIFKDFGVDHIIEGGQTMNPSTEDFMNAIKHINAKNIFIFPNNSNIIM
                     AANQAKELSDKNIIVIPTKNTPQGFAALVTFNGELSEDENKEAMMNALNSVKSGQVTF
                     AVRDTVMNEIDVKEGNIIGIAEGNLLSAGDYVDEVTSNLIEKLVDEDTAIITLFFGED
                     VTESQANELRTSLEEKFEDVDVELYYGGQPLYYYLISVE"
     gene            2233..4290
                     /gene="recG"
                     /locus_tag="PC512_003404"
     CDS             2233..4290
                     /gene="recG"
                     /locus_tag="PC512_003404"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HDF2443120.1"
                     /translation="MDLYKDVQYVKGIGPKKADKLNKLGIFTLKDLLYYFPRQFEDRN
                     NLKKIAQLEDGEKVTIKAVISSINTFSPKEGMTLTKIDVKDETGSAKLVFFNKSYIKN
                     TFRPGDSILVFGKVKKKFNNLELTSCELEYLTNSPKNTCRFMPVYQLTYGVTNKEIMS
                     IIRTVLEDKELIIQEYMPQRIIEKYRLCSIDFAVRNIHSPSSKESLKIALYRIVFEEL
                     LILQLGLFVFKSGRNKEDGIKFETSKDLKKIISALPFKLTKAQNRALDEIIQDMNLEK
                     IMNRLVQGDVGSGKTVVALLALANCVLNGYQGALMAPTEILAGQHYISLTESLKDFGI
                     NVGLLIGSLTKKQKDTVLEQIKNNEIDILIGTHALIEDKVEFNNIGLVITDEQHRFGV
                     MQRSKLSLKGANPDILVMTATPIPRTLALILYGDLDISIIDELPPGRQPIETIAIEKS
                     KRDRAYNNLVRREVESGRQVYIVCPLVEESEAIEAKSAVELVEELRAEYFHDLRLGLL
                     HGKMKSSEKDEVMRLFKDKEIDILVSTTVIEVGVNVPNATLMIIENAERFGLAQLHQL
                     RGRVGRGSHKSYCVLIYDSKTDVCRQRMAIMEETNDGFKISEKDLEIRGPGEFFGTRQ
                     HGLPELKVANLFKHIKILKLAQQEARYILGEDNNLQLKENMALKKEIIDKFKDTLKEI
                     SLN"
     gene            4349..4903
                     /gene="rsmD"
                     /locus_tag="PC512_003405"
     CDS             4349..4903
                     /gene="rsmD"
                     /locus_tag="PC512_003405"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HDF2443121.1"
                     /translation="MRVISGKARGLKLNTPKNEDVRPTTDRVKESLFNMINSYIMESE
                     VLDLFAGTGSLGIECLSRGAKSCTFVDISKESIDIVKSNIKKARVESESIILNLDFKT
                     AIDKLKLQNSKFDIIFMDPPYYKNMFIEAIEKIDNSNLLNEDGIIVVEHDTNDLFPDK
                     ICKLEKTRDKKYGNTTLTFYKMEA"
     gene            4905..5402
                     /gene="coaD"
                     /locus_tag="PC512_003406"
     CDS             4905..5402
                     /gene="coaD"
                     /locus_tag="PC512_003406"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HDF2443122.1"
                     /translation="MENKPRKAIFAGSFDPITNGHLDIICRASKLFDELQIGVLNNPN
                     KKGLFSFDERVKLIEKSTSHLNNIKVVTFDGLLINYCQENGIGALVRGVRSGADVDYE
                     LQMAHMNRELNPDIETIILPSCTKYSFISSSLIKEVLLFDADIKNLVPKIVLEELKKK
                     TSGGN"
     gene            5406..5930
                     /locus_tag="PC512_003407"
     CDS             5406..5930
                     /locus_tag="PC512_003407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443123.1"
                     /translation="MKIDLEMIELFEQLEEIFRSASTIPFSHKCTVDKDEVLAIINDI
                     RTLIPEEVTQAVWINKERNKIISQAKQDATNIVEQAKKEAERIQQEYQDNIEELKKNS
                     EDVVKAYVESSEPVVQADQRAKDIVDRAERIANEIRIGSIEYAEDVLSSVEYNLREIL
                     EEVKRDKAELRPKK"
     gene            6274..8193
                     /locus_tag="PC512_003408"
     CDS             6274..8193
                     /locus_tag="PC512_003408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF2443124.1"
                     /translation="MKERAKKILDFIIKNNNVTSQELQEKFNVSKRTIYYDILAINEQ
                     LGKSGNIKNVKHKFIFEGNLCDARKIISTEEDKFLDSDYRKTFILNKILLGEKISIEK
                     LTNEMLLSKNTVVQTITDVKKYLQTMGLRLEYKGKYKIIGDEYVIRELFLIIVQENVL
                     EINSISEEVSSFDTKGHIKLTDYSLLNLTKFVEFLNKRIRDGKTLYSYKYLNEAKKIS
                     YFSNCKELLCEEANENEQAYICTYISSLPSLNSEVKEDVVEEYVDKLIDKFEVNTAIK
                     LESKHEFKKNILRHLHSSYNRIRFKFPIRNPMLDETKYKHESLYKIIKSIIENEEEFP
                     VFEGIREEEIGFIAAYFGGYLRGSRDNGLRRNKVLLVCPNGLMVSKSLEIQLYKYIPT
                     IEIVGIVSIKQLKEVNVYYDYIITTIDIQNVNNVIVVNPLLTSSDVQLLMNKLISVKE
                     NEKYFNLELIIQAIRKNGVINNEEALKADLLNIIHKIDEGEMYQPMLKELINAERVNI
                     IKNVRDWKEAIKIASKPLLEDNSIEELYIENMIKSVEKYGPYIVLADRFALPHASSKE
                     GVNKLAMSLLIVEDEVDLLGKPVNIFMVLAAVDNTTHIRALASLSEMMYEEENVKLII
                     NGDKSSIIELINKQN"
     gene            8206..8493
                     /locus_tag="PC512_003409"
     CDS             8206..8493
                     /locus_tag="PC512_003409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2443125.1"
                     /translation="MKILAVCGFGVGSSMVLKMTIQKALKQLGIECEVENTDINSARG
                     ADCDCIFTSQELLNELKGTCNVDVYPVKKYMDLAEVTEVVQTFLSDKNDKK"
BASE COUNT         3595 a          889 c         1604 g         2573 t
ORIGIN      
        1 atccaaaaac ttttctaggt ttaaattata ccatatttat agtatgatat gattataatt
       61 ttatataata aataagtaaa aatagtaaaa aataaattaa gaaatgtttt taataaaaat
      121 aagcttaagg gggtcaacca tgagtgcaaa ggtaacgaat caatatggaa atatagaaat
      181 agataatcaa gtaatagctc aagtcgtata tagagctgca atggaaagtt atggcttagt
      241 aggtttagca tataagtcta aaggaatagt agagctatta aaaggcgaga acgcaactaa
      301 aggtgtaaga gttgaggaag tagaagaaga tgccatagca atcgaacttt atgttataat
      361 acaatatggt acaaatatat ctactgttgc caataatata atagatagag taaaatatgt
      421 agttgaaaaa atgactggcg taagagttac tagaattgat attaatgtac aaggaataag
      481 agttaagtaa tttcatagga ggaaacaaat gattcaatat atagatggta aaaggttaag
      541 ggagatgttt atttcaggtg caaacaatct ccaaaacaat aaagagttag ttgacaagtt
      601 aaatgtattc cctgtaccag atggagatac aggaactaat atgtcattaa caatatctta
      661 tgccttaaaa gaattagcaa aagttgaaaa tgataatata tcagatatcg gaaaagcatt
      721 atctaaaggt tctttaatgg gagctagagg aaactcagga gttatacttt cacaaataat
      781 cagaggtata gctaaatcta tagaaggaaa aagtaaatta tcaacagaag atttagcaaa
      841 agcttttaaa aatggttcag acacagcata taaagctgta ataaaaccaa ttgaaggaac
      901 tatacttact gtagttagag aaagtggaga gtttgcaata aaaactgcga aaaaagagaa
      961 agatgtagta aagtttttaa gtatgcttgt gaaggaatca aattcttcat tagaaagaac
     1021 tccagacctt ctaaagaatc taaaagaagc tggtgtggtt gactctggtg gaaagggtct
     1081 tgtacttata tatgaaggaa tgttagcttc tataaaaggc gataacatag aaataaaaaa
     1141 tgttgaccta gatactaata tttcaacaag tatggatttt gcaaagagta ctactagcac
     1201 agatgatata aaatattgct attgtacaga atttatttta gaaagttcta aggtagaaga
     1261 tactaaaata agagacataa tgatggctta tggtgatagc ctagcagtag ttggagatga
     1321 tggagtcata aaggtacatg tacacactaa tgacccagga aatgtacttc aagaagctct
     1381 aaagtacggt caattattaa ctataaaaat agaaaatatg aagttacaac atgaaaatac
     1441 attactggat gtagaagaaa agaaagaaaa tgatagtgaa cctttagaag aagaaaaaga
     1501 gtttgggttt atagctactt ctatgggtga aggtttggca aatatattta aagatttcgg
     1561 agttgaccat ataatagaag gtggtcaaac tatgaatcca agtactgaag attttatgaa
     1621 tgctataaag catataaatg ctaaaaatat atttattttc ccaaataaca gcaatataat
     1681 aatggctgct aatcaggcaa aagaattgag tgataaaaat ataatagtta tacctacaaa
     1741 aaatacgcct caaggatttg ctgcattagt aacttttaat ggagaattaa gcgaagatga
     1801 aaataaagaa gctatgatga atgctttaaa ctcagttaaa tcaggtcaag taacttttgc
     1861 tgttagggat acagtgatga acgaaattga tgttaaagaa ggtaatataa ttggaattgc
     1921 agaagggaat ttattatcag caggagatta tgtggatgaa gtaacatcaa accttattga
     1981 aaagttggtt gatgaagata ctgctataat aacattattc tttggtgaag atgttacaga
     2041 atctcaagca aatgaactac gtacttcttt agaagaaaag tttgaagatg tagatgtaga
     2101 gttatattat ggaggacaac ctctttatta ttacttaatt tcagttgaat aatgattata
     2161 agaacctgta tgaccaagta gcttttataa aattggttgt acaggatttt tgtgtagtag
     2221 gtgatatatt tgttggattt atataaagat gttcaatatg ttaagggaat aggacctaaa
     2281 aaagcagata aattaaataa actgggtata tttacactaa aagacctatt gtattatttt
     2341 ccaagacaat ttgaagatag aaataatcta aagaaaatag cacaattaga agatggtgag
     2401 aaagttacga taaaagcagt aatatcaagt ataaatacat ttagcccaaa agaaggtatg
     2461 actttaacaa agattgatgt aaaagatgag acaggctcgg ctaaattagt gttttttaat
     2521 aagagttata taaaaaatac ttttcgtcca ggagattcaa tattagtttt tgggaaggtt
     2581 aagaaaaaat ttaataactt agaacttaca tcatgtgaat tagaatatct tactaattca
     2641 cctaagaata catgtagatt tatgcctgtg taccagctta catacggtgt tacaaataaa
     2701 gaaattatga gtataattag aacagtactt gaagataaag aattaattat acaagaatat
     2761 atgccacaaa gaattataga aaaatatagg ctatgtagta tagattttgc agttagaaac
     2821 atacattcac caagtagtaa ggaatcatta aaaatagctt tatatagaat tgtatttgaa
     2881 gaattactta tactacaact agggttgttt gtatttaaaa gtggcagaaa taaagaagat
     2941 ggaataaagt ttgaaacaag taaagactta aaaaaaataa taagtgcttt accatttaaa
     3001 ctgactaaag ctcaaaacag ggcattagat gaaattatac aagatatgaa tttagagaaa
     3061 ataatgaata gattggtaca aggtgatgta gggagtggta aaacagtagt agctctctta
     3121 gcacttgcaa attgtgtttt aaatggttat cagggcgctt tgatggcacc tacagagata
     3181 ttagcagggc aacattatat ttcacttact gagtctctaa aagattttgg aataaatgta
     3241 ggtctattaa taggtagtct tacaaaaaaa caaaaggata cagtattgga acaaataaag
     3301 aataatgaga ttgatatatt aataggtaca catgcactaa ttgaagataa ggttgaattt
     3361 aataatattg gtttagttat aacagatgaa caacatagat ttggtgttat gcaaaggagc
     3421 aaactttcat tgaaaggagc aaatcctgat atattagtaa tgacagcaac accaatacca
     3481 agaactttag cacttatact ctatggagat ttagatattt ctattataga tgaacttcct
     3541 ccaggaagac agccaataga aacaattgct attgaaaaaa gtaagcgaga tagagcatat
     3601 aataaccttg taagaagaga ggttgaatca ggaagacaag tgtacattgt atgtcccttg
     3661 gtagaagaaa gtgaagccat agaagccaaa tcagcagttg aacttgttga ggagttaaga
     3721 gcggaatatt ttcacgactt aaggcttggg ttgcttcatg gtaaaatgaa gtcaagtgaa
     3781 aaagatgaag taatgagact ttttaaagat aaagaaatag atattttagt ttcaacaaca
     3841 gtaatagaag ttggtgtcaa tgtgccaaat gcaacattaa tgataataga aaatgcagaa
     3901 agatttggac ttgcacaatt acatcagctt agagggcgag ttggaagagg tagtcataaa
     3961 tcgtattgtg tactaattta tgattctaaa acagatgtat gtagacaaag aatggctata
     4021 atggaagaga ccaatgatgg ttttaagatt tcagagaagg atttagaaat aagaggacct
     4081 ggggaatttt ttgggacaag gcagcatggt cttccagaac ttaaggtagc aaacttattt
     4141 aagcatataa aaatactgaa gttagcacag caagaagctc gatatatatt gggtgaagat
     4201 aataatctac aattaaaaga aaacatggca ctcaaaaaag aaattataga taaatttaaa
     4261 gatacattga aagaaatttc attaaattaa ttttaaattg tgttaaaata ttactaatgt
     4321 aataatgtgc tgaagggaga ttgtcatatt gagagtaatt tcaggaaaag cgagaggatt
     4381 aaaactaaat actccaaaaa atgaagatgt aaggccaact acagatagag taaaagagtc
     4441 tctatttaat atgataaatt catatataat ggaaagtgaa gttctggatt tatttgctgg
     4501 gactggttct ttaggaatag agtgcttatc taggggtgcc aagtcatgta cttttgtaga
     4561 tatcagtaag gaaagcatag atattgttaa gtccaatata aaaaaggcaa gagttgaaag
     4621 tgaaagtatt attttaaacc ttgattttaa gactgcaata gataaactta aattacaaaa
     4681 tagtaaattt gacataattt ttatggaccc tccgtattat aaaaatatgt ttatagaagc
     4741 tattgaaaaa attgataatt ctaatctatt gaacgaagat ggaataatag ttgtagaaca
     4801 tgatacgaat gatttatttc cagataagat atgtaaattg gagaaaacta gagataagaa
     4861 atatggaaat actacattaa ctttttataa gatggaggca taatatggaa aataaaccta
     4921 gaaaagctat atttgcagga agttttgacc caattactaa tggacattta gatattattt
     4981 gcagggcttc gaagttattt gacgaattac aaataggagt attaaataat cctaataaaa
     5041 agggtctatt tagctttgat gaaagagtaa aacttataga aaaaagtaca agccatttaa
     5101 ataatataaa agttgtgact tttgatggtt tattaataaa ttactgtcag gaaaatggga
     5161 ttggagcatt agttagaggt gtgagaagtg gtgctgatgt tgattatgaa cttcagatgg
     5221 cgcatatgaa tagagagctt aatccagata tagagactat aattttacca agttgtacaa
     5281 aatattcatt tataagttca tctttaataa aagaggtttt gctctttgat gctgatataa
     5341 aaaatttggt tccaaagatt gttttggaag aattaaagaa aaaaactagt gggggtaatt
     5401 gatatatgaa gatagattta gaaatgattg aactatttga gcagttagag gagatattta
     5461 gaagtgcttc tacaatccct ttctcacata aatgcacagt ggataaagat gaggttttag
     5521 caataattaa tgatataaga actttaatac cagaagaagt aacacaggca gtatggatta
     5581 ataaagaaag aaataaaata ataagtcaag ctaagcaaga tgctacaaat atagttgaac
     5641 aagcgaaaaa agaagctgag agaatacaac aagaatatca agataatata gaggaattaa
     5701 agaaaaattc tgaagatgta gtaaaggcat atgtagaatc cagtgaacct gttgttcaag
     5761 cagaccaaag agcaaaagat atagttgata gagctgagag aatagccaat gagataagaa
     5821 ttgggtcaat tgaatatgca gaggatgtgc tttctagtgt tgagtataat ttaagagaaa
     5881 tattagaaga agtaaaaaga gataaagctg aacttagacc taaaaaataa attttaaata
     5941 aataaaaatg gagctatcac acaaaaaatt ccaatttatg tgtgatagct ctcttttaat
     6001 atagcaattt tttgttatat aattgtgctt tttagattac ttatatctta ttttgatatt
     6061 ataatgtagt ttaatctttt atttgttgaa atcaacttat ttatttgtat aaataatata
     6121 ggttattttc aaattttttt aataatttta ccactgtctt cttttagatt agagttagac
     6181 tgtgcaaaat tataaaataa tactaaatca tgtgcaatta tttggtatgg cactacatgt
     6241 agaaaatata gataataaaa ttaaggaggt agtatgaagg aaagggctaa aaaaatatta
     6301 gattttatta ttaaaaataa caatgtaaca tcacaagaac tacaagaaaa gtttaatgtt
     6361 tcaaagagaa ctatttatta cgatattcta gctataaatg aacaactagg aaaaagtggt
     6421 aatataaaaa atgtaaaaca caaatttata tttgaaggta atttatgtga tgcaaggaaa
     6481 ataatttcaa ctgaagaaga taaattttta gatagtgatt acagaaaaac ttttatatta
     6541 aacaagatat tacttggcga aaaaatatca atagaaaaac taacaaatga aatgttactt
     6601 tcaaaaaaca cagtagtaca aacaataact gatgtaaaaa aataccttca aacaatgggg
     6661 ttaagattag agtataaggg aaagtacaaa attataggtg atgaatacgt tattagagag
     6721 ctgtttctga taattgttca agaaaatgta ctggaaatta attctataag tgaggaagta
     6781 agtagtttcg atacaaaagg acatataaaa cttactgatt attctttatt aaatctaact
     6841 aagtttgtgg aatttctaaa taaaaggata agagatggga aaacattata ctcatataaa
     6901 tatctaaatg aagctaaaaa aattagttac tttagtaatt gtaaagaact tttatgtgaa
     6961 gaagctaatg aaaatgaaca agcctatata tgcacttaca taagttcact tcccagctta
     7021 aatagtgaag ttaaggaaga tgttgttgaa gaatatgtag ataaacttat agataagttt
     7081 gaagtaaata cagcaataaa attagaaagt aagcatgagt ttaagaaaaa tattttaagg
     7141 cacctccact cttcttacaa cagaatacga tttaagtttc ctattagaaa tccaatgtta
     7201 gatgagacta agtataaaca tgagtcactt tataaaatta taaaatcaat tatagagaat
     7261 gaagaagagt ttcctgtatt tgaggggata agagaagaag aaataggatt tatagcagcg
     7321 tattttggag gatatttaag agggtctagg gataatggtc taagaagaaa taaagtctta
     7381 ctagtttgtc ctaatggtct tatggtatca aagagtttgg aaatacaact atataaatac
     7441 ataccaacca tagaaatagt aggtatagta tccattaagc aactaaaaga agtaaatgta
     7501 tactacgatt acataattac aactatagat atacaaaatg taaacaacgt aattgttgta
     7561 aatcctcttt taacatcatc agatgttcaa ttacttatga acaaactaat aagtgtaaaa
     7621 gaaaacgaga agtatttcaa tcttgaatta ataatacaag ctataagaaa aaatggagtt
     7681 atcaataatg aagaagcact aaaagctgat ttattaaaca taatacacaa gatagatgaa
     7741 ggagagatgt atcaaccaat gttaaaggaa ttaattaatg cagaaagggt caatataata
     7801 aaaaatgtta gagattggaa agaagcaata aaaatagcct caaagccatt gttagaagat
     7861 aactctatag aagagttata tatagaaaat atgataaagt cagttgagaa atatggacca
     7921 tatattgttt tagctgatag atttgctcta ccacatgcaa gttctaaaga aggagtaaac
     7981 aagcttgcta tgtctttact aatagtagaa gatgaagttg atttattagg aaaaccagta
     8041 aatatattta tggtattagc tgctgtagat aacactactc acattagagc attagcatca
     8101 ctatcagaga tgatgtacga ggaagaaaat gtaaaactaa taattaatgg tgataaaagt
     8161 tcaataatag aacttataaa taagcaaaat tagggggaat gaaaaatgaa gatattagca
     8221 gtatgtggtt ttggtgtagg ttcatcaatg gtattaaaaa tgacaatcca aaaggctcta
     8281 aagcagttag gtatagaatg tgaagtagaa aatacagata taaattcagc tagaggtgct
     8341 gattgtgact gtatattcac aagtcaagaa ttgttaaatg aattaaaagg aacttgtaat
     8401 gtagatgtat atccagttaa aaagtacatg gatttagcag aagtcacaga agttgttcaa
     8461 acttttttaa gtgataaaaa tgataagaaa tagtataagt tttaaaaagt aaatttaagt
     8521 taatcagaat aaaataaaaa cttactaagt tcaaaaatag taagaaagag aggagggatt
     8581 tagtggtaga aaacttaaac agttgaccta tcactaaaaa atataatgct tgattaaaaa
     8641 atagctacgc acactcgtga c
//
LOCUS       DAMJVG010000119         8638 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.124, whole genome shotgun sequence.
ACCESSION   DAMJVG010000119 DAMJVG010000000
VERSION     DAMJVG010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8638)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8638)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8638
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.124"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            158..1081
                     /locus_tag="PC512_003410"
     CDS             158..1081
                     /locus_tag="PC512_003410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2520 domain-containing protein"
                     /protein_id="HDF2443126.1"
                     /translation="MGSGKVGTSLANYFLSKGYCVSGFYGRNQLSLLESTNLTKTKIY
                     SNLKDIIYENDILFITTSDDSIEIIDKKLSKFNLKHKYICHTSGSLKSSILFCSKKAG
                     ALIYSIHPIFAFSNKNTNIKKMKDICFSIEGDNEQDDLVIQNFIDDLGNQFFIRDKDT
                     SSTYHLANVLVSNLVLSLLDIGVSYFIKLGLSEEESLKAISPLVKKNIENILDNGFTK
                     ALTGPVSRGDITPIRKHLSVLDKKDEDIYKILSLNLLKIIALGNDNSLKGIKNITIEN
                     AIENLISKSEKYKEIYKLLGGKNDEKYHTDF"
     gene            1056..1883
                     /gene="panB"
                     /locus_tag="PC512_003411"
     CDS             1056..1883
                     /gene="panB"
                     /locus_tag="PC512_003411"
                     /EC_number="2.1.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="HDF2443127.1"
                     /translation="MKNTIQTFKNAKYEGKKLSMLTAYDYSIAKIMDECDINGILIGD
                     SLGMVIKGEENTLSVTIDEIIYHTKAVKNGVKNALIVSDMPFLSYHVSIEDAVKNAGR
                     LIKEGGAHAVKLEGGSNVIKQIESIVNAQIPVMGHLGLTPQSVNSFGGFKVQGNTSET
                     ARQLIEDAKLIEKAGAFSIVLEGVPTKIAEMVTNSISIPTIGIGAGINCDGQILVYQD
                     MLGMFGDFVPKFVKQYANIGDIMKDSIKNYILEVNTGTFPQEKHSFSINESELEKLY"
     gene            1902..2750
                     /locus_tag="PC512_003412"
     CDS             1902..2750
                     /locus_tag="PC512_003412"
                     /EC_number="6.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HDF2443128.1"
                     /translation="MLVKEIKLLRNIIKDWRKHGYSIGLVTTMGFLHEGHQSLIKKAV
                     KENDKVVVSVFVNPTQFGPNEDFNSYPRDIDKDFKYCMDSGATVVFNPSPEEMYLKGN
                     CTTINVSGLTDFLCGAKRPVHFGGVCLVVSKFLNIVTPDKAYFGEKDAQQLAVIKRMV
                     KDLNIDTEIIGCPIIRENDGLAKSSRNTYLSEEERKSALILNKSLSLAKEELVKGNLN
                     PENIKELITAKINSEHLAKIDYVEIVDSETLQPVKQIEHSILVAIAVFIGKTRLIDNF
                     TFELNI"
     gene            3161..3343
                     /locus_tag="PC512_003413"
     CDS             3161..3343
                     /locus_tag="PC512_003413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443129.1"
                     /translation="MFKDKIDECVHIMTAYIASLKEYYSFIETQIGDFIKKYGEDVVE
                     LCLHRVMILLCECGLA"
     gene            4175..5089
                     /locus_tag="PC512_003414"
     CDS             4175..5089
                     /locus_tag="PC512_003414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2935 domain-containing protein"
                     /protein_id="HDF2443130.1"
                     /translation="MIDNQKYVILSLELHLFFSRIMKEHALFLEAGFTNKNYNLAMEA
                     DHYKKQFEDLLSYTVSASNGIIRPDILYSEELVTTLTSVAEQKTEEFTGIEINKNITT
                     RELNLQSGVNPQVGQDLVNYVAQLNSDAIRLLDGLINFKERVLDGVLSCTIFTSNYPL
                     LLEHIIHEANLYRYYVVDLENKIDIESKNAKEIELFWDHIMMEHALFMRGLLDPSEGE
                     LINTSNDFAIKFNELIEKTNEMTDSNIKNITEETLNETVEFKDFKEAGASGIEQCKIK
                     SIILPLLADHVLREANHYIRILESYKNM"
     gene            5479..6126
                     /locus_tag="PC512_003415"
     CDS             5479..6126
                     /locus_tag="PC512_003415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein"
                     /protein_id="HDF2443131.1"
                     /translation="MIRQTPLEKRYDKLGPHIVTALKKRYFDAYYCKTRNEALQQILD
                     LIPQNHVVSWGGSETLKEMGVQTAVREKGFKVIDRDLAKTPEERTEIMRQALLCDTFL
                     MSSNAISEDGQLFNIDGNGNRVAAMIFGPKNVIVVAGMNKIVKNIDDAIQRTRTIASP
                     AVVQRFQDVNTPCYINGSCIDCTSPESICAYMVTTRISRPAKKIKVILVGENLGL"
     gene            complement(6293..6862)
                     /locus_tag="PC512_003416"
     CDS             complement(6293..6862)
                     /locus_tag="PC512_003416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDF2443132.1"
                     /translation="MKKFIICIIMFAISVLVLAGCTNDNKIKNEVDSMFNSIKTQDAD
                     TVDKYFPKSGLGNLIYEDKEGFKMYSKNMTWEISDIKNNKDKVTVDLKINNTDMVSIL
                     KKNPPKLGEMMPNPTMKDIDSAKKKEFNITLELVKSGDNYVCKVNQESAMKLLNVITG
                     GGIDYLADYNKDYYKQLDEEQKNYENKNS"
     gene            complement(6867..7766)
                     /locus_tag="PC512_003417"
     CDS             complement(6867..7766)
                     /locus_tag="PC512_003417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF2443133.1"
                     /translation="MKLLSKVNNNIRLITQVAFTALTNGYVNGFLEGTIYGGESKKLC
                     VPGLNCYSCPGALGACPIGSLQAVLSSREYKFSFYVVGFLMAFGAFFGRFVCGWLCPF
                     GLVQDLLHKVPFPVKIKKVYGDKYLKYLKYIVLIMFVIILPVAIVNVAGGGNPWFCKW
                     ICPSGTLLGGILLILGNENLRESIGFLFSWKLSILLLILLMSIITYRPFCKYICPLGA
                     IYGFFNPISIYRFKIDKDKCTNCTACQTKCKLDIPIYKDVNSPDCIRCGECIKVCPQN
                     AITTTFSKDKKENNICAKKYRGI"
     gene            complement(7777..7926)
                     /locus_tag="PC512_003418"
     CDS             complement(7777..7926)
                     /locus_tag="PC512_003418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443134.1"
                     /translation="MSNFIKDNKKGISIIAISIIFIALGTYRGETNTVLTKAIMICLE
                     CIGIG"
     gene            complement(7919..8503)
                     /locus_tag="PC512_003419"
     CDS             complement(7919..8503)
                     /locus_tag="PC512_003419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HDF2443135.1"
                     /translation="MKRFFIVVLGCICVLGMISGCSKKESKPVEKNKNNSEWFSNLDT
                     EDVDGNKVTKEIFSNKELTLINVWTTWCGPCVGEMPELEALSKEYESNNSNVAIKGLV
                     VEVDKTDMRTGLSNEEKNLVKDIMKKSDATYQQLTVSEELKKTDFKRVMEFPTTYFVD
                     KKGNFVGEKVVGANSKEDWKKIIDERLKMVKANE"
BASE COUNT         3279 a         1202 c         1125 g         3032 t
ORIGIN      
        1 aaaatggtaa gatatttatg gatggtatct tgttataaga actatacttt aaatgttttt
       61 aattattttg tcttatgtaa ctcatatcct caggaatgag attagaaatt aagatgttgt
      121 atcacaaagt ggaggtgata ctattaaaat aggctttatt ggttctggaa aagttggaac
      181 atctttggca aattattttt tatcaaaagg ttattgtgtt tcaggctttt atggaaggaa
      241 tcaattatct ttattagaat caacaaattt aacaaaaaca aagatttaca gcaatttgaa
      301 agatataatt tatgaaaacg atatattatt tattacaaca tcagatgatt ctattgaaat
      361 tatagacaaa aaactttcca aatttaattt aaaacataaa tacatttgcc acacaagtgg
      421 ctctttaaaa tctagtatat tgttctgttc aaaaaaagca ggtgcattaa tttattctat
      481 ccatcctata tttgcatttt ccaataaaaa taccaacata aaaaaaatga aagacatttg
      541 tttttccata gaaggtgata atgaacaaga tgatttagtt attcaaaatt tcatagatga
      601 tttgggaaac caatttttta taagagataa ggatacttca tccacttatc atttagctaa
      661 tgttttagtt tcaaatttag tattatcttt actagatata ggagtaagtt actttattaa
      721 attaggttta tctgaagagg aatctttaaa agctatcagt cctttagtaa aaaaaaatat
      781 agaaaatata cttgataatg gctttactaa agctcttact ggtcctgttt ctcgtggaga
      841 tataacacca ataagaaaac atctatctgt attggataaa aaagatgagg atatttacaa
      901 aatactatcc ttaaacctac taaaaataat tgccttagga aatgacaatt cattaaaagg
      961 tataaaaaat attactatag aaaatgcaat cgaaaattta ataagtaaat ctgaaaaata
     1021 caaagaaatt tacaaacttt taggaggaaa aaacgatgaa aaataccata cagactttta
     1081 agaatgctaa atatgaagga aaaaaactat ctatgcttac tgcttatgac tactcaattg
     1141 caaaaataat ggatgagtgt gatataaatg gtattttaat aggagattca ttaggaatgg
     1201 ttataaaagg tgaagaaaac actctatctg ttaccataga tgaaattata tatcatacaa
     1261 aagctgtaaa aaatggtgta aaaaatgcct taatcgtaag tgatatgcct tttctatctt
     1321 accatgtttc tatagaagat gcagttaaaa acgcgggtag acttataaaa gaaggaggag
     1381 ctcatgctgt aaagttagaa ggtggctcaa acgttataaa gcaaatagaa agcattgtaa
     1441 atgctcaaat acctgtaatg gggcatttag gattaactcc tcaatcagta aattcatttg
     1501 gtgggtttaa ggttcaagga aataccagtg aaacagcaag acaacttatt gaagatgcta
     1561 aattaataga aaaagcaggt gcattctcta ttgtccttga aggagtgcct acgaaaatag
     1621 ctgagatggt aactaattct atttcaattc ctacaatagg tataggggca ggaattaact
     1681 gtgatggaca aattttagtt tatcaagata tgttgggaat gtttggagat tttgttccta
     1741 agtttgtaaa gcagtatgca aatataggag atataatgaa agattcaatt aaaaattaca
     1801 tcctagaagt taatacaggt acatttccac aagaaaaaca cagcttttca ataaatgaat
     1861 ctgagttaga aaaattatac taatattaag gatggtacaa aatgcttgta aaagaaatta
     1921 aattactaag aaatataatc aaagattgga gaaaacatgg ctattctata gggcttgtta
     1981 caacaatggg atttttacat gaaggacacc aaagtcttat aaaaaaagct gtaaaagaaa
     2041 atgataaagt agtagtgagt gtatttgtaa atccaactca atttggacca aatgaagatt
     2101 ttaatagcta tccaagagat atagataaag attttaaata ttgtatggat agtggagcaa
     2161 cagtagtctt taacccatca ccagaagaaa tgtatttaaa aggtaattgt actaccatta
     2221 atgtttctgg acttacagat tttctttgtg gagctaaaag acctgttcat tttggaggtg
     2281 tctgcctagt tgtttcaaag tttctaaata tagtaacacc tgataaagct tattttggag
     2341 agaaggatgc ccaacaatta gctgtaatta aaagaatggt caaggattta aacatagata
     2401 cagaaataat aggctgtcct ataattcgtg aaaatgatgg attagcaaaa agttcgagaa
     2461 atacatatct ctctgaggaa gaacgaaaat ctgctctaat attaaataag agcttaagtt
     2521 tagcaaaaga agaattagta aaaggcaatc taaatccaga gaatataaaa gaattaataa
     2581 cagctaaaat aaattctgaa cacttagcaa aaatagacta tgttgaaatt gtagatagtg
     2641 agacattaca acctgttaag caaatagaac attctatact tgtggcaatt gctgtgttta
     2701 taggaaaaac cagactaatt gataatttta catttgagtt aaatatatag tctataattt
     2761 tatataatat atctaaaaaa taatagaata cctaaaaagt aataaattac ctaaaaaata
     2821 ataaattgct tagaaaataa tagattacaa taactaaaat tttaaaatta aattccttaa
     2881 aagtatgatt aattataatt atataagtat attcttatta cacttatatt aatttatatt
     2941 aaatatctac taactcaaat attcataatt aaactttaaa ctggataaat tttcttttaa
     3001 gaatgaaagt ttatccagtt ttgcgattat aataaccagt tttacatatc cacttgtaaa
     3061 atatatctaa gcaatatatc atactatata gatttatgag tgaaataata tctgctattt
     3121 actgaatatt tttatttttc gttttttagg gggattagtt gtgtttaaag ataagattga
     3181 tgaatgtgtt catataatga ctgcatatat tgctagttta aaagaatact attcattcat
     3241 agaaactcaa attggtgatt ttattaaaaa atatggagaa gatgttgtag agttatgtct
     3301 ccatagagtg atgattctac tatgcgaatg tggtttggca taaaattaaa tttattaaaa
     3361 tgggtaagaa gaatcctata taatattctt cttacccatt ttaatatatc aatttcatag
     3421 cttatcgttt aaaatatttt acatccatta ctagacaact ttacattctc tttttaattc
     3481 tagtatattt aaatcatttt agttgctcct tatttattct tattacttgt tttattttat
     3541 aaataaaata attcttttta ataatgtttt ttgttgatat tcctatcaca catccaatta
     3601 tttatcattg tcttgaaatt gtttgcatac ttaatttaat ccaattgaaa caccccagca
     3661 tagaatcccc tgtaaaatag aagttggatt aaatcctaac atctatacag aaaatactac
     3721 tccaagcaca agcaatataa tggaatatat ttatcactta attttttata ctttttaaat
     3781 cccataccta aagcattaag tgcagctatt agaattaata attgttgtgg tataaaatta
     3841 tgcttgcttc atatttattc attttttact ataaaagttc ttgttttaca aaaaacattt
     3901 gttttgtatc aaaataatac ttgtaaatta cataattctc ataaaaattt ctagtattac
     3961 ttgtactctt aataaataat agccaacaag taccttaaat cattatatct atatctaata
     4021 agaaacacag taagataatt ttttcgccca taacttaata aaaactgttg atattagtag
     4081 caattgaatt tagttaattt atttataata tacataaatt taaatattac gaataaagta
     4141 ttataaatag gatactttct aaagggagga aattatgata gataatcaaa aatatgttat
     4201 tttatcacta gaattacatt tatttttttc aagaattatg aaagagcatg ctcttttttt
     4261 agaagcagga ttcacaaata aaaattataa tcttgctatg gaagctgacc actataaaaa
     4321 gcaatttgaa gatttattat catacactgt tagtgctagt aatggtataa ttagacctga
     4381 tatattatat tcagaagagc ttgtaactac tctcacatca gttgcagaac aaaaaacaga
     4441 agagtttaca gggatagaaa taaacaaaaa catcactaca agagaattaa atctacaaag
     4501 tggtgtaaac ccacaagttg gtcaagactt agtgaactat gtagctcaac ttaactctga
     4561 tgcaataaga ttacttgatg ggcttattaa ttttaaagaa agagtcttag atggtgtact
     4621 atcatgtact atatttacat caaactaccc tctacttctt gaacatataa tacatgaagc
     4681 aaatttatat cgttattatg tagttgacct tgaaaataaa atagatattg agtcaaaaaa
     4741 cgctaaagaa atagaattat tctgggacca tattatgatg gaacatgctc tgtttatgag
     4801 aggattacta gacccctcag aaggtgaact aataaatact tcaaatgatt ttgctataaa
     4861 atttaatgaa ttaattgaaa aaacaaacga aatgactgat tctaatatca agaacattac
     4921 agaagaaact ctaaatgaaa ctgttgagtt taaagatttt aaagaagcag gagcatcagg
     4981 aatagaacag tgtaagataa aatctataat attaccactt ttagcagacc atgttttaag
     5041 agaggcaaat cattatatta gaatattgga gagttataaa aacatgtaat taaaaattac
     5101 ttttaaaata atctttgcat atttagataa aataaaggta cagttaactg tacctttatt
     5161 ttttataaac ttataaaatt taaacaagtt attcataaaa taaaataata atcatctata
     5221 acccacaact ttattttata ttaaataaaa agtattagtg attatgtttt ataggtattt
     5281 ctttattcag ttatttatta aaaactaata gtaaatctta tactaatcgc atatttatgt
     5341 tataactata ttgtaactat tttcgtaatc ttaggaaaag attacttata aaattaacct
     5401 tatacaataa tatatcgtat aatcttaatt agcataatag ttacaatatt aaaatttaaa
     5461 tatgggagtg attttagtat gataagacaa acaccattag agaaacgata tgacaagcta
     5521 ggtcctcata ttgtaacagc actcaaaaaa cgttattttg atgcttatta ctgtaaaact
     5581 agaaatgaag ctttgcaaca aattttagat ttaattcctc aaaatcatgt agtatcatgg
     5641 ggaggatctg aaacacttaa agaaatgggc gtacaaactg ctgttagaga gaaaggattt
     5701 aaagttattg atagagattt agcaaaaact ccagaagaaa gaactgaaat tatgcgtcaa
     5761 gcacttctat gcgatacttt tttgatgagt agcaatgcaa ttagtgaaga tggacaactc
     5821 tttaatattg atggaaatgg caatcgtgta gctgcaatga tatttggtcc aaaaaatgtt
     5881 atagttgtag ctggtatgaa taaaattgta aaaaacattg atgatgcaat acaaagaact
     5941 agaacaattg catctccagc agttgttcag cgttttcaag atgtcaatac accatgctat
     6001 attaatggaa gttgtataga ttgcacaagc cctgaaagca tttgtgcata catggttact
     6061 acaagaatca gtcgtccagc aaaaaaaata aaggtaatat tggtaggaga aaatcttggt
     6121 ctataaaata tacatacatg taaatagctc tataaataat aaaatcatat gaaataactt
     6181 atttctaaaa gtggtagaat aaaagcttct acaagacttt cattctacca cttttatatt
     6241 cttttaattt gtgtttctat attattaatt gctccgattt tcatatatat tactaactat
     6301 ttttattttc ataatttttt tgttcttcat caagctgttt ataataatct ttattatagt
     6361 cagctagata atctatacca cctcctgtaa tcacatttaa taatttcatt gcagattctt
     6421 gattaacttt acaaacataa ttatcaccag atttaacaag ctctaatgta atattaaatt
     6481 cttttttctt tgcagaatca atatctttca tagttggatt tggcatcatt tctcctagtt
     6541 taggaggatt cttttttaaa atagaaacca tatcagtatt gttaattttt aaatctacag
     6601 tcactttatc cttattattc tttatatctg aaatttccca agtcatattt ttagaataca
     6661 ttttaaatcc ttctttatct tcgtatataa gattacctaa ccctgatttt gggaaatact
     6721 tatcaacagt atctgcatct tgtgttttta ttgaattaaa catactatcc acttcatttt
     6781 ttatcttatt atcattagta caaccagcta acaccagtac tgatattgca aacattataa
     6841 tacatataat aaatttcttc attaaattat atccccctat acttttttgc acaaatatta
     6901 ttctcttttt tatcttttga aaaagttgta gtaattgcat tttgtggaca aacttttata
     6961 cattcaccac acctaataca gtctggacta tttacatctt tatatattgg tatatcaagc
     7021 ttacattttg tttgacatgc tgtacaattt gtacatttat ctttatcaat tttaaatcta
     7081 tatattgaaa taggattaaa aaaaccatag attgctccta aagggcatat atacttgcaa
     7141 aatggcctat aagtaatgat tgacatcaat aatatcaata gcaaaatact taacttccag
     7201 ctaaataaaa atcctattga ttctcttaaa ttctcatttc ctaaaataag tagtattcct
     7261 cccaaaagtg ttcctgaagg gcaaatccat ttacaaaacc aaggatttcc accccctgct
     7321 acatttacaa tagcaactgg caaaataatt acaaacatta ttaagactat atactttaga
     7381 tattttagat atttatcacc ataaactttt tttatcttta ctggaaaggg tactttatgt
     7441 agtaaatctt gtacaagtcc aaagggacaa agccaaccac aaacaaatct gccaaaaaaa
     7501 gcaccaaatg ccattaaaaa accaacaaca taaaatgaga atttatactc tctgcttgat
     7561 aaaactgctt gtaatgaacc tattggacat gctccaagtg cacctggaca tgaataacaa
     7621 ttcaatccag gtacacataa ttttttactt tctcctccat atatagttcc ttctaaaaat
     7681 ccatttacat atccatttgt taatgctgta aatgcaactt gagtaataag tcttatatta
     7741 ttatttacct tagataataa cttcatccct cttctcctaa ccaataccaa tacactcaag
     7801 acaaatcata attgctttag ttaatactgt atttgtttct ccacgatatg tacctaatgc
     7861 aataaatata atactaattg caataataga aatgcctttt ttattatctt taataaagtt
     7921 actcattggc ttttaccatt tttagtcttt catctataat ttttttccaa tcttccttac
     7981 tatttgcacc tacaaccttc tcacccacaa agtttccttt cttgtctaca aaataagttg
     8041 ttggaaactc cataactctt ttaaaatcag tttttttaag ttcttcagat acagtcaatt
     8101 gttggtaagt tgcatctgac tttttcataa tgtctttaac taaatttttc tcttcatttg
     8161 aaagaccagt tctcatatca gttttatcaa cttctacaac taatcccttt atagctacat
     8221 tggaattatt actctcatat tcttttgata atgcttcaag ctctggcatt tcacccacac
     8281 atggtccaca ccaagtagtc cagacattaa taagagtaag ttctttattt gaaaatatct
     8341 cttttgttac cttatttcca tcaacatcct ccgtatctaa attactaaac cattcactat
     8401 tattcttgtt tttttctact ggcttagatt cttttttgct acatccagaa atcataccta
     8461 aaacacaaat acatcctaaa actactatga aaaacctttt catatctcac actcctagaa
     8521 tttatatagt atataaaatc gctgcttgaa ataaaaataa cttatcttct atattaaagt
     8581 aattatattt aataaataag agctaattta aaaaaagata tacagttaaa atctattt
//
LOCUS       DAMJVG010000120         8473 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.125, whole genome shotgun sequence.
ACCESSION   DAMJVG010000120 DAMJVG010000000
VERSION     DAMJVG010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8473)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8473)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8473
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.125"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            6..2183
                     /locus_tag="PC512_003420"
     CDS             6..2183
                     /locus_tag="PC512_003420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HDF2443136.1"
                     /translation="MYNKYNNLYLLLGKENVNMDSYRQLKAKIPCKETGIEIKRTLCD
                     ICSPGVHCGIDAYVKDGKVIKIEGTKEHPMNKGLLCTKGLCNREYIYREDRIKTPLKR
                     IGKRGEGKFKPISWDEAYREIAEKLNRVKSEYGAKHVAFFTGYGKWYRPFLQRFASSF
                     GSPNYGTESSSCSTSAQMAGNVATGRNFTMQDMENAKTYLGWGFNPYYSKFLNSVNLI
                     KLKEKGLKFIIVDPRITPTTQKLADLHLRIKPGTDGALALGMANLFIQKDLIDREYIE
                     KHVHGFNEYKEYVKLFDLDTVSRITGVSKDNIVKAVEMLSQGPFCINESAAPIVHHQN
                     GFQNYRAMMSLSAITGNYDRIGGNIPKQDYFAGKIGGFQTLEKEFVKEVLPKNINERI
                     GGERFPLWNEMVTQFQAMDLPRQIEEKTPYEIRALFCHGINARMFTNSGRLFKALNSV
                     DFFVNIDLFMTDTSKYADILLPACTSFEREECKSYPGGYITYTKKVIDKLYDSKSDVE
                     ILSDLANAMNIDDDLLKAGYEASIRHMFKNTCVDVDKLKESDLPLKCKDFKPYIVGSY
                     TREGYDTSTSRFELKSTIIEKYKDFGLDALPTYRGFNDNIDDEYTHLLTSGARISNAL
                     HSRLHDIKLSRILKNEASCDISSLDAKELGVISGDYIKITTKIGSLDVKVNVTDRVLY
                     KNIHMYHGYREADINSIICDNFDPYSGFPAYRSCKCKIEKMNR"
     gene            2197..2619
                     /locus_tag="PC512_003421"
     CDS             2197..2619
                     /locus_tag="PC512_003421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF2443137.1"
                     /translation="MKSLFKFNKELCTACGACLLACIDQNDNNIDNGELFRHVFTIEE
                     GENIEYFSLACIHCNEPKCLGVCPKNCFKKEEGFIVLDNQNCIGCKLCEKACEYGALI
                     YGNDGKANKCNGCIERYKCGMDSPCVMVCPTGALKFNK"
     gene            3027..3830
                     /locus_tag="PC512_003422"
     CDS             3027..3830
                     /locus_tag="PC512_003422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HDF2443138.1"
                     /translation="MKKLKLIIMFALVSALLVTGCSSGNNKNKEEQKVIRVATSGTYY
                     PFAFKDKDKLKGFEVDFWDEFAKRTNCKVEWVLTDFSGLFGLLEADKADVVSAQLTAT
                     PEREKKYAFSDAYNYSGTNIIVREDDTSIKSIDDLVGKKVGVGTGAVANEILKEKYPN
                     DEIKIVNYSSATLKGNYQDLEMGRLDAVVAQDVEALIAIKEQKLNLKMIEPPIQFGAC
                     SFALQKNEKGEKWTKEINEVIEEMYKDGTLTKISENWLGKDITKEPINE"
     gene            3823..4491
                     /locus_tag="PC512_003423"
     CDS             3823..4491
                     /locus_tag="PC512_003423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDF2443139.1"
                     /translation="MSNFNFEFCLSIFPFLIKALGITILISIVAFFLSILLGVILAFF
                     TQTKSKVLQYITRVYVSFFRGTPLLIQIFFFYFGFPMIFSFMKDCSPYLAIVICLGVN
                     SSAYMAEIIRASIESVDKGQQEACYAFGLSKYQSMVKIILPQAATSAVPPIVSCTLDI
                     IKGSSLGLTIGIQDLMGVAQVEAASSFKYFEIYMITILIYWAVSIILSNIQSKVEKRI
                     RRAY"
     gene            4727..5389
                     /locus_tag="PC512_003424"
     CDS             4727..5389
                     /locus_tag="PC512_003424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDF2443140.1"
                     /translation="MAFNMKYFLELFPTIMKSFNVTVILAISSLVFSLIIGTIVALSS
                     YYKVKVLNQICKVYVSIFRGTPLMPQLFFLYFGLAYMSDFVKNMDPVFATSIVLSLNM
                     GAYMSETIRASILSIDTGQIEAAYAMGLTNLQTMKRIVIPQAVRVALPSLFNNFIDLI
                     KGSSVAFVVGVNDIMGAAKSQGALSFKFFEVYGAVMVIYWCIITPLGWGQKKLEKKIS
                     NY"
     gene            5449..6246
                     /locus_tag="PC512_003425"
     CDS             5449..6246
                     /locus_tag="PC512_003425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF2443141.1"
                     /translation="MIKRNIIKCLVAVLSLTFVITGCSKKEEVKNEKVITVASSNSAD
                     PYSYVDNGEHKGFEVDMWKEIGKRSGYKIKMEPTGFSSIFGMLDSGKVDVAANFFGMS
                     KERLEKYDASIPYGSDSVCIAVKDGNNEINKLEDLKGKVVAVSEGSQGQQVATSVNKD
                     NLFQEKVYGDGTSGLQDLDLGRVSAWIDAELTIVGDAKKANMKVRVLDKKLSATNIAY
                     FFKKNDDKSKTIKEDVNKAIEEMLADGTVKKISEKWFGMDVSADIQK"
     gene            6364..7554
                     /locus_tag="PC512_003426"
     CDS             6364..7554
                     /locus_tag="PC512_003426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2443142.1"
                     /translation="MEVLQMIETKIKSIALKNREKIIKIRRQIHSNPELAFKEYKTSK
                     LIKEELNKLNIEYINIAGTGVLATIKGKNNGGKTILLRADMDALPIKEENDLEFKSIN
                     DNMHACGHDAHVSWLLGTAMILNDIKEELNGNVKLLFQPGEEKGGSDIVIKENVLEGV
                     DALATGHCWPTIESGKIGIARNCAMAATNTFEITIIGKGGHGAEPHNCIDPIAVGNAV
                     YSSIQQIVSRKIDPVVPVVVSVCSFNSGVSKNIIPDVCTLQGTIRAISKEQVIEVSKI
                     LEYIVKNVCKAHGADCKFEKSTGGDAVINDKNMIEIGRESACKILGAENVEIIDFPAM
                     TGEDFAIYMKEKPGLFMYIGVGDKEKNINYRLHSNKFNIDEKCLSIAPSLFSQLTVDY
                     LCQL"
     gene            7663..8412
                     /locus_tag="PC512_003427"
     CDS             7663..8412
                     /locus_tag="PC512_003427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HDF2443143.1"
                     /translation="MIKVENLHKSFKGTEVLKGINLEISQSEVVAILGSSGTGKSTLL
                     RCLNYLVEPTKGKIMIGDVKVDVEKATKKDITNLRKHTSMVFQNYNLFKNKTALENVM
                     EALIVVHKKSKKEAREISLKLIDKVGMLDRKDFYPSKLSGGQQQRIGIARAMAVNPNV
                     ILFDEPTSALDPELVGEVLSVIKSLAKEGITMLIVTHEINFAKEVADKIIFMDNGVIA
                     EEGTPDEIFNNPKNERTAKFLNIIRKEEVFS"
BASE COUNT         3356 a          856 c         1577 g         2684 t
ORIGIN      
        1 aaagaatgta taataagtat aataatttgt atttattatt gggaaaggaa aatgttaata
       61 tggatagtta tagacaactt aaagctaaaa taccctgtaa ggaaacaggt atagaaataa
      121 agaggacttt atgtgatatt tgttctccag gagtacattg tggaattgat gcatatgtta
      181 aagatggtaa agtaataaaa atagaaggta caaaagaaca tccaatgaat aaagggttgt
      241 tatgtaccaa aggtctttgc aatagagaat atatctatag agaagataga ataaaaacac
      301 ctctaaaaag aattggaaaa agaggtgaag gaaaatttaa accaatatca tgggatgaag
      361 cttatagaga aatagcagaa aaattaaata gagtaaaatc tgagtatgga gcaaagcatg
      421 tagctttttt tacgggttat ggaaagtggt atagaccttt tttacaaagg tttgcatctt
      481 catttggttc acctaattat ggtacagaat ctagttcatg ttcaacatca gcacagatgg
      541 ctggaaatgt tgctactgga agaaacttta caatgcaaga tatggagaat gcaaaaactt
      601 atttagggtg gggatttaat ccatactact ctaaattttt aaatagtgtg aatctaataa
      661 aattaaaaga aaaaggtcta aaatttataa ttgtagaccc tagaataaca ccgacaactc
      721 aaaaactagc agatttacat ttaagaatta aacctggaac tgatggagct ttagctcttg
      781 gaatggcgaa tctatttata caaaaggatt taatagatag agaatacata gaaaagcatg
      841 tacatggatt taatgaatat aaagaatatg taaaattatt tgatttagat actgtaagta
      901 gaattacagg agtttctaaa gataatatag taaaagctgt cgagatgttg tcacaaggtc
      961 cattttgtat aaatgaaagt gcagctccaa tagttcacca tcaaaatgga tttcaaaatt
     1021 atagagcaat gatgtcttta tccgctataa caggtaatta tgatagaata ggtggaaaca
     1081 taccaaaaca agattacttt gctggtaaga taggtggatt ccaaacacta gaaaaagagt
     1141 ttgtaaaaga agttctacct aaaaatataa atgaaagaat tggtggagaa agatttcctc
     1201 tatggaatga aatggtgact caatttcaag ctatggattt acctaggcaa atagaagaaa
     1261 agacaccata tgaaataaga gctttgtttt gtcatgggat aaatgctaga atgtttacta
     1321 attcagggag actttttaaa gcgttgaata gtgtagattt ttttgtgaat atagatttat
     1381 ttatgacaga tacatcaaaa tatgcagata tacttttacc tgcatgtaca tcatttgaga
     1441 gagaagaatg taagagttat ccaggagggt atattacata taccaaaaaa gttattgata
     1501 aattatacga ttcaaaatca gatgtagaaa tactttcaga tttagcaaat gctatgaata
     1561 tagatgatga tttattaaaa gcaggttatg aagcaagtat aagacatatg tttaaaaata
     1621 catgtgtaga tgtagataaa cttaaagaaa gtgatttacc attaaaatgt aaagatttta
     1681 agccatatat agtaggttca tatacaagag aagggtatga tactagcact tctaggtttg
     1741 aattaaaatc tacaattatt gaaaaatata aagattttgg gctggatgca ctaccaacat
     1801 atagaggatt taatgataat atagatgatg aatatactca tttattgaca tcaggagcaa
     1861 gaatttcaaa tgcactacat tcaagacttc atgacatcaa actttcaaga atattaaaaa
     1921 atgaagctag ttgtgatatt tctagcttag atgcaaaaga attgggtgtt atcagtggag
     1981 attatataaa aataactact aagataggaa gtttggatgt aaaagtcaat gttactgata
     2041 gagtcttata taagaatata catatgtatc atggatatag agaagctgat ataaatagta
     2101 ttatttgtga taattttgac ccttatagtg gattccctgc gtatagaagt tgtaagtgta
     2161 agattgaaaa aatgaataga taaatggaga gatataatga aaagtttatt taaatttaat
     2221 aaagaattat gtacagcatg tggagcatgt ttgcttgcat gtatagacca aaatgataat
     2281 aatatagaca atggtgaact ttttagacat gtatttacaa tagaggaagg tgaaaatata
     2341 gaatattttt cattagcatg tatacattgt aatgagccaa aatgtttagg tgtatgtcct
     2401 aaaaattgtt ttaaaaaaga agaaggattc attgtattag acaatcaaaa ctgtataggg
     2461 tgtaaacttt gtgaaaaagc ttgtgaatat ggagccttaa tttatggaaa tgatggtaag
     2521 gcaaataagt gtaatggttg tattgagaga tataagtgtg gtatggattc accttgtgta
     2581 atggtatgtc ctacaggagc attaaaattt aataaataaa ttaaatatag agaatgactt
     2641 atacttaggt ataagatatt tttacaaaaa gctgtattga gtttgttata atgaaaactc
     2701 aatatagctt ttttatggat atagttggat actataatgt gattcttagt aatagttttt
     2761 tgctattgga caaagactgt aaaacatatt aaacttatgt tgttcaaagt cgaagtataa
     2821 tataataact agaaaattgg tttatagtgc tataaaagca aatttagtaa ggtataaaat
     2881 cagaggcaat cctttactat aatatcaata tttgggagtt ctgttattgc agagctatta
     2941 aacaattata atggtacaag tgattcaacc tttgaaaatg tattatataa aaaattaaaa
     3001 taagattaaa aaggagagaa taaattatga aaaaacttaa attaattatt atgtttgcct
     3061 tggtatcagc actgttagtt acaggatgtt catcaggaaa taataaaaat aaagaagaac
     3121 aaaaagttat aagagttgca acatcaggaa catattaccc ttttgctttt aaagataaag
     3181 ataaacttaa agggtttgaa gtagattttt gggatgaatt tgctaaacga actaattgta
     3241 aagttgaatg ggtattaact gattttagtg gattatttgg attattagaa gctgataaag
     3301 cagatgttgt atctgctcaa cttactgcaa cacctgaaag agagaaaaaa tatgcttttt
     3361 cagatgctta taattatagt ggaacaaaca ttattgttag agaagatgat actagtataa
     3421 aatcaataga tgatttagtt ggcaagaaag taggtgtggg tactggagca gtagcaaatg
     3481 aaatattaaa agaaaaatac ccaaatgatg aaataaaaat agtaaattat tcaagtgcga
     3541 ctcttaaagg gaattatcaa gacctagaaa tgggaagatt agatgcagta gttgcgcagg
     3601 atgttgaggc tttaatagct ataaaagaac aaaaattaaa tcttaaaatg atagaacctc
     3661 caattcaatt tggtgcctgt tcttttgcgc ttcaaaaaaa tgaaaaaggt gaaaaatgga
     3721 caaaagaaat taacgaagta attgaagaga tgtataaaga tgggactttg actaaaatat
     3781 ctgaaaactg gctaggaaaa gacattacta aggagcctat taatgagtaa ttttaatttt
     3841 gaattttgtc taagtatatt tccatttttg attaaagcat tgggaataac aatactaata
     3901 tctattgttg catttttttt atcaatatta ttaggtgtaa tacttgcctt tttcacacag
     3961 acaaaatcaa aagttttaca atacataaca agagtgtatg tttcattctt tagaggaaca
     4021 ccacttttaa ttcaaatatt tttcttttat tttggatttc caatgatatt ttcttttatg
     4081 aaagattgtt caccttattt agcaatagta atttgtttag gtgtaaattc atctgcatat
     4141 atggctgaaa ttatacgagc atctattgag agtgttgata aaggacaaca ggaagcatgt
     4201 tatgcttttg ggttaagtaa atatcagtca atggttaaaa taattctacc tcaagcagct
     4261 acatctgcag tacctcctat tgtaagctgt acactggaca taattaaagg ttcttcttta
     4321 ggtttaacta taggaataca agatttaatg ggagtagctc aagtagaggc tgcttcaagt
     4381 tttaaatatt ttgagatata tatgataacg atattaattt actgggcagt atctataata
     4441 ttgagtaata tacaaagcaa agttgaaaaa agaataagaa gagcatatta gatttcaata
     4501 tttaaaaatg ggatgatata gatatattat tacttgtaaa taaattttta attttagaaa
     4561 aataaactta gtaatctaaa ttattgagaa aatatagtat caaaatggac tgtataatca
     4621 agttaaaaaa tagtttttct attgaaaaaa taaataaaat tctattgtaa tttaatatgc
     4681 gataaagttt tataaaaaac aacattaagc tagggggact tattttatgg cttttaatat
     4741 gaaatatttt ttagaattat ttccaacaat aatgaaatcg ttcaatgtaa ctgtgatttt
     4801 ggcaataagt tcattagtat tttcattaat tataggtaca atagtagcgt tatcatctta
     4861 ttacaaagtg aaagtattga atcaaatatg taaagtatat gtatctattt ttagaggtac
     4921 acctcttatg ccacagttat tctttttata ttttggacta gcatatatga gtgattttgt
     4981 taaaaatatg gacccagtat ttgcaacatc tatagtactt agtttaaata tgggagctta
     5041 tatgtctgaa acgataaggg catctatact ttcaattgat acaggtcaga tagaagcagc
     5101 atatgcaatg ggattaacaa atttacaaac aatgaaaagg atagtgatac cacaggccgt
     5161 aagagttgca ctgccatcat tattcaataa ttttatagat ttaattaaag ggtcttctgt
     5221 agcttttgtt gttggagtaa atgatataat gggtgctgcc aaatcacaag gagcgttgag
     5281 ttttaagttt tttgaagtgt atggagcagt tatggtaatt tactggtgta taataactcc
     5341 tttaggttgg gggcaaaaaa aattagaaaa gaaaataagc aattattaag ttattaagaa
     5401 aatacataaa agtattttta tataaaaaat ggtgtgagga gaagagatat gataaaaaga
     5461 aatattataa aatgtttagt ggcagtttta tcgttaacgt ttgtaattac tggttgttca
     5521 aaaaaagagg aagtaaagaa tgaaaaagtt ataactgtag cttcatctaa ttcagctgac
     5581 ccatattctt atgttgataa tggtgagcat aagggttttg aagttgacat gtggaaagag
     5641 attggtaaaa gaagtggata taagataaaa atggaaccaa caggttttag ttctatattt
     5701 ggtatgttag attctggtaa agttgatgtg gcagccaact tctttggaat gtctaaagaa
     5761 agattagaaa aatacgatgc ttctatacct tatggttctg attctgtgtg tatagctgta
     5821 aaagatggaa ataacgaaat taataagctt gaagatttaa agggaaaagt tgtagcagtt
     5881 tcagaaggtt ctcaaggtca acaggttgca actagtgtta ataaagataa tttgtttcaa
     5941 gaaaaggttt acggtgatgg aactagtggt cttcaagatt tagatttggg aagagttagt
     6001 gcatggattg atgcagagct tactattgtg ggagacgcta aaaaagctaa tatgaaagta
     6061 agagtattag ataaaaaatt atcagctact aatatagcat acttctttaa gaaaaacgat
     6121 gataaatcta aaacgataaa agaagatgta aacaaagcaa tagaagaaat gcttgcagat
     6181 ggaacagtga aaaaaatatc tgaaaaatgg tttggaatgg atgtaagtgc tgatatacaa
     6241 aaataaatac tttaaaatta aaatgtaaaa ctgtgataac tatagataag tatactaaat
     6301 ttatctatag ttatctgtgt attacaatgt atttagatta gtctttataa atcaaaatga
     6361 gttatggagg tattgcaaat gattgaaact aaaataaaat ccattgcact aaaaaataga
     6421 gaaaaaatta taaaaataag acgacagata cacagtaatc cagagttagc atttaaagaa
     6481 tataaaacat ctaaacttat aaaagaagag ctaaataaac ttaatataga atacataaat
     6541 attgctggta caggagtatt agctactata aaaggaaaaa ataatggtgg aaaaactata
     6601 ttactcagag cggatatgga tgctcttcca atcaaagagg aaaatgattt agaatttaaa
     6661 tcaataaatg ataatatgca tgcttgtggg catgatgcac atgtttcatg gttgttagga
     6721 acagcaatga ttttaaatga cataaaagaa gaattgaatg gaaatgtaaa attactattt
     6781 caacctggcg aagaaaaagg tggttctgat attgtaatta aagaaaatgt acttgaaggt
     6841 gtggatgcat tagcgactgg tcattgttgg ccaactattg agtcaggaaa aattggaatc
     6901 gctagaaatt gtgctatggc agcgactaat acttttgaaa taacaataat tggcaagggt
     6961 gggcatggag cagagcctca taattgtata gacccaattg cagttggaaa tgcagtatat
     7021 tcatccattc aacagatagt ttcaagaaaa attgacccag ttgtacctgt agtagtgtct
     7081 gtttgttctt ttaattctgg tgtttctaaa aatataatac cagatgtatg tacacttcaa
     7141 gggactatta gagcgataag caaggaacaa gtaattgaag taagtaaaat tctagaatat
     7201 atagtaaaaa atgtatgtaa agcacatgga gcagattgca aatttgaaaa gagtacagga
     7261 ggagatgctg ttataaatga caaaaacatg atagagatag gaagagaaag tgcttgcaaa
     7321 atacttggag ctgaaaatgt tgaaataatt gattttcctg caatgacagg tgaggatttt
     7381 gctatttata tgaaagaaaa acctggttta tttatgtata taggtgtagg agataaagaa
     7441 aaaaatataa attacagatt gcatagtaac aagtttaata tagatgaaaa atgtcttagt
     7501 atagcacctt cattattttc acaacttaca gtagattatt tatgtcaact atagagtaca
     7561 ttcataaaaa tatatttagc ctatttttaa atttaatgct agtatattaa ttttgatgta
     7621 gaacatatta tttattatat ttatttaaaa aggtggataa caatgataaa agtagaaaat
     7681 ttacataaaa gttttaaagg gacagaagtt cttaaaggta taaatttaga gataagtcaa
     7741 agtgaagtag tagctatact tggatcatct ggaacaggta aatctacgtt acttagatgt
     7801 ttaaattatt tagttgagcc tacaaaagga aagataatga ttggtgatgt aaaagtagat
     7861 gtagaaaaag caacaaaaaa agatataacc aatttaagaa aacatacatc tatggtgttt
     7921 caaaattata acttatttaa aaataaaaca gcattagaaa atgtaatgga ggcattgata
     7981 gtagttcata aaaagagtaa gaaagaagct agagaaatat ctttaaaatt aatagataaa
     8041 gtaggtatgt tggataggaa agatttttat ccatcaaagt tgtctggggg acagcaacaa
     8101 aggataggta tagcgagagc gatggcagta aatccaaatg taatattatt tgatgagcct
     8161 acatctgcac ttgacccaga acttgttgga gaagttttaa gcgttataaa atctcttgca
     8221 aaagaaggta taacgatgct tattgtaact cacgaaataa attttgcaaa agaagttgct
     8281 gataaaatta tatttatgga taatggtgta atagctgaag aaggaactcc tgatgaaata
     8341 tttaataatc ctaaaaatga aagaacagca aaatttttaa atatcattag gaaagaagaa
     8401 gtatttagtt aaaagtgtat aaattaagca ttagaagata tgtaagatac ccccattaaa
     8461 tttataagtt aga
//
LOCUS       DAMJVG010000121         8375 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.126, whole genome shotgun sequence.
ACCESSION   DAMJVG010000121 DAMJVG010000000
VERSION     DAMJVG010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8375)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8375)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8375
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.126"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            94..849
                     /locus_tag="PC512_003428"
     CDS             94..849
                     /locus_tag="PC512_003428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2443144.1"
                     /translation="MLQIKNLSKSFPNPYGEPNTIFENLSIDIEDGEFVSIIGSNGTG
                     KSTLLNIISGLIKESSGQVLLNKHNLSNLAEHRRTQIVSRVFQDPSLGTCPSMTVREN
                     LSLALNKGKLLNLRKCLRYKRDFLENLLEGVSLDLKKYLDVQVKFLSGGQRQSLSLIM
                     SCLTNPSVLLLDEHTAALDPKTSNEVIELTNKIVREKNITTLMVTHNLKHALHYGDRL
                     IMLHKGEVVLDVKGKEKEQLTVEEILEKFEYAV"
     gene            980..2002
                     /locus_tag="PC512_003429"
     CDS             980..2002
                     /locus_tag="PC512_003429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2443145.1"
                     /translation="MINKKRLASLILAGALSISMLTGCSQGGDSGNSKQESNSKGKEV
                     KKIGITQLVEHPALDATRTGFVKALEKNGFKDGENIDIDFQNAQNDMPTTQSIASKFA
                     SDKKDLIFAISTPSAQAAFNATKDIPILITAVSDPVAAGLVKTLEKPGTNVSGTSDFV
                     SVDKGLELLKIFAPKAKTIGVMYNTSEVNSKVQVDALKEYASKNGFKVVEKGITTSNE
                     VNQGISSLVGKIDVLYVPTDNLVASSMPIVSKIATENKIPVIAAESGPVEKGALACQG
                     INYEKLGYKTGEMAVKILNGESVSDMPVATSDDTDIIVNEDILKALGMEKPSNENISY
                     VKTKQE"
     gene            complement(2166..2723)
                     /locus_tag="PC512_003430"
     CDS             complement(2166..2723)
                     /locus_tag="PC512_003430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HDF2443146.1"
                     /translation="MTEKEKMLSGKGYYANDELLVKEREYCKKLTRLFNNTLEDEYEK
                     REDILRQLFGSVGKQINVEQNIRCDYGYNIHVGENFFANYDCIFLDVCKIEIGDNVML
                     APNVQIYTAYHPIDAQLRNSGIEYGSPVKIGDNVWIGGGVIITPGITIGDNVVIGAGS
                     VVTKDIPPNTVAVGNPCRVIKKIEE"
     gene            complement(2729..3805)
                     /locus_tag="PC512_003431"
     CDS             complement(2729..3805)
                     /locus_tag="PC512_003431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/molybdate ABC transporter ATP-binding
                     protein"
                     /protein_id="HDF2443147.1"
                     /translation="MSLYVDIEKDLSSFKLKVEIKQEKGTLGFLGESGSGKSMTLKCI
                     AGLEKPTRGKIVLNDRVLFDSEKKINLSTQDRKVGFLFQNYALFPHMTVSQNIELGLL
                     KLSKSEKKEIVARYLDILKLNGFEGRYPWQLSGGQQQRVALARALATSPDILLLDEPF
                     SALDHHLRSNMEKELMNMLKDYKGDILFVTHDIEEAYRVCDDIIVYNKGEGLPKRPKK
                     ELFESPKYLIEAKITGCKNISKLNRLDKNTIYATDWGCELTLNREIGDNIEYVGIREH
                     HIKVLDSNEDLNEKLCFELINIVENPFTYTIYVRKTDLSNECVPIQIELEKSKMRFKK
                     GDRIYLDFPQEYLFCFRYNYNKKE"
     gene            complement(3806..4489)
                     /gene="modB"
                     /locus_tag="PC512_003432"
     CDS             complement(3806..4489)
                     /gene="modB"
                     /locus_tag="PC512_003432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter permease subunit"
                     /protein_id="HDF2443148.1"
                     /translation="MGTDWSPLWISLKTSILSTIITFVIGIFVSYIMANYRGKWKGLI
                     DGLFTLPLILPPTVVGFFLLLLCGKNGFIGKFLLNFDRTLIFSWTATVISAVVVSFPM
                     MYRTSRSAFEQIDNNMLSAARTLGLNEWKVFFKIAVPLAWPGIIGGLVLSFARALGEF
                     GATLMIAGNIPGKTQTMPIAIFFAVEGGDMNKAMMWVMIIVAISIAMILLLNYWSEFQ
                     QKIIGKRCG"
     gene            complement(4638..5450)
                     /gene="modA"
                     /locus_tag="PC512_003433"
     CDS             complement(4638..5450)
                     /gene="modA"
                     /locus_tag="PC512_003433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF2443149.1"
                     /translation="MKKILGILGLVACLTLGTVGCNSNEDKKDDGKQEKTTKSSDSVE
                     LNISAAASLKEAMAKIEEEYKKVDSNVKLTVNYGASGSLQQQIEQGAPCDLFISAGQK
                     QMKALDEEKLLVSDTMKDLVKNDLVLISSADSSVSGMEDLTTDKVKKIAVGEAESVPA
                     GKYADEVLTNLNLKDKLKDKLVFAKDVKEVLAWVQSGNADVGFVYFSDTVNNDKIKVV
                     EKTDEKTHSPITYPVSVIKASKNVDAAKKFEEFLLSESGQKIFEEFGYKKVE"
     gene            5643..6572
                     /locus_tag="PC512_003434"
     CDS             5643..6572
                     /locus_tag="PC512_003434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2443150.1"
                     /translation="MDSLSSLTPVEVAELLKITKNTVYELIKRGELPSYKVGKKIRVD
                     TKDVEEYINSQKTGKVKDTHFNNKNIDINNNFKIIISGQDVILDILARSVEKKLDGIS
                     TFRSYIGSYNALYELYNGRVSIASSHLWDFETDEYNSTFVKKLLPGIPCVLINLAYRM
                     QGFYVAKGNPKEITTWEDLTKPSITIVNREKGSGTRVLLDGKLRLLNFNGKHIKGYDN
                     EELSHLGVASTVSRGIADVGLGNEKAALQVNNIDFIPLHKERYDLVIKKEDLQNPVYQ
                     TIINIINSPEFKAELQGLGGYDLTDTGKTIAKV"
     gene            complement(6733..7182)
                     /locus_tag="PC512_003435"
     CDS             complement(6733..7182)
                     /locus_tag="PC512_003435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443151.1"
                     /translation="MKNKNNKDKNMLNIKVLRVLGVLLILFDYTGDTLNFYNFFAKPL
                     VSGNLYKTTGTDCIVFLLFIVECVYLVGRYILKVKINWSEIIENEKGNFINNLLVEKI
                     QEESNIVYNLLNSYVLPNIYKKARGLMFKTYHMLIYIKEKYYYVNIY"
     gene            complement(7385..8365)
                     /locus_tag="PC512_003436"
     CDS             complement(7385..8365)
                     /locus_tag="PC512_003436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2443152.1"
                     /translation="MKNSFKNCISLRNKFIIISIVFLLILLIVSYIFGKLVYNSSVGL
                     EQLIKNEDIVKIFSERKDKPLEKLKNYKTSELMIQSSNNYKLESLFITSNIKTRDTMI
                     LVHGIGSSYYEMLKVAYRYLDKGYNVLVYNQRNTGNSGGDNYTFGLYERYDLDSLVKF
                     VKNKFPEGRLGVHGFSMGAGTAAMHSEINSKDDKVDFYILDSPYSEMKDAIRMGVLEK
                     RIPDILINYVVTCGDLYNKFKSGFWYSDVKPYESVEKSNVPILFIHGTKDTVCNYQNS
                     KKMYDLVKHDKKDLWLIEGIGHVDGFEHDSTVYFNKIFKFIDSNVLSDKS"
BASE COUNT         2914 a         1379 c         1012 g         3070 t
ORIGIN      
        1 ctttcctagc tactggtaac ttaaatattt cactaaaaaa aaacaaatgc aaagctagta
       61 ccaaaaataa atcagaaaaa agaggtgttg tagatgttac aaattaaaaa tctttcaaag
      121 agcttcccta atccatatgg tgaacctaat actatctttg aaaatttatc aatcgatata
      181 gaagatggtg aatttgtaag tatcataggt agtaatggaa ctggtaaatc tactttatta
      241 aatataatat ccgggcttat aaaagaatct tctggtcaag tattattaaa taaacataac
      301 ttgtctaatt tagctgaaca cagaagaact caaatagtaa gtagagtttt tcaagaccca
      361 agtcttggaa cttgcccttc tatgactgtt agagaaaact tgtctttagc tcttaacaaa
      421 ggaaaactat taaatctaag aaaatgtctt cgttacaaaa gagatttctt agaaaattta
      481 ttggaaggtg tatctcttga tttaaaaaaa taccttgatg ttcaagtaaa atttttatca
      541 ggaggtcaaa gacaatcatt atcactaatt atgtcgtgct taacaaatcc atcagtttta
      601 ttacttgatg aacatacagc agcacttgac ccaaaaacat caaatgaagt aattgaattg
      661 actaataaga ttgtaaggga aaaaaatata actacactta tggttactca caacttaaaa
      721 cacgctcttc attatggtga tagattgata atgcttcata agggtgaagt tgtattagat
      781 gtaaaaggta aagaaaaaga acaattaaca gttgaagaaa tcttagaaaa atttgaatat
      841 gcagtttaaa ataatatatc tattgtatta aactcggctt taaaataaag ttaaaattac
      901 aataattatg gttactttgt aataattcat atgaatatat gaacatatat aataataaat
      961 ttttgagggg gatataaaaa tgattaataa aaaaagattg gcaagtttga ttttagctgg
     1021 tgctcttagt atatctatgc ttacagggtg ttcacaagga ggagactctg gtaattcaaa
     1081 acaagaaagt aattctaaag gtaaagaagt taaaaaaatt ggtataactc aactggttga
     1141 acatccagca ttagatgcca ctaggacagg ttttgtaaaa gcattagaaa agaacggatt
     1201 taaagatgga gaaaatattg atatagactt ccaaaatgct caaaatgaca tgcctactac
     1261 acaaagtatt gcgagtaaat ttgcatctga taagaaggac ttaatatttg ctatatctac
     1321 tccatcagct caggcagcat ttaatgctac taaagatata cctatactta ttactgctgt
     1381 gagtgaccct gttgctgctg gattagttaa aactcttgaa aagccaggca caaatgtatc
     1441 tggaacatca gattttgttt ctgtagacaa aggtttagaa cttcttaaaa tatttgctcc
     1501 taaggcaaaa actataggag ttatgtacaa tactagtgaa gtaaattcca aagtccaagt
     1561 tgatgcttta aaagaatatg catctaaaaa tggatttaaa gttgttgaaa aaggtataac
     1621 tacttcaaat gaagttaacc aaggtatttc tagtttagtt ggcaaaatag acgtattata
     1681 tgttcctaca gataacttag tggcttcttc tatgcctata gtctctaaaa tagctactga
     1741 gaataaaata cctgttatag cagctgaatc tgggccagtt gaaaaaggtg ctcttgcttg
     1801 tcaaggtatc aactacgaaa aactaggtta caaaacaggt gaaatggcag ttaaaatttt
     1861 aaatggtgaa tcagtatctg atatgcctgt ggctacatca gatgatacag atatcattgt
     1921 taatgaagat atattaaaag ctttaggtat ggaaaaacct tctaatgaaa atatttctta
     1981 tgtaaagact aaacaagaat agaaagatat tttctatata cgattaatat gcctgtttct
     2041 ataaattaat ttatagaaac aggcatatat ttttatttta atgtattatc tatttaaaga
     2101 ttatatgtaa atgctcttaa tttgtttgta taaattttac ttgtataaac tttatacaat
     2161 catatttatt cttctatttt ctttattact ctacatggat ttccaacagc tacagtattt
     2221 ggtggtatat cttttgtgac tacacttcct gcacctatta ctacattatc acctatagta
     2281 attcctggtg ttatgattac tcccccacct atccatacat tatcacctat ttttacagga
     2341 gaaccatact ctatacctga atttctaagt tgtgcatcaa ttggatgata ggctgtatag
     2401 atttgaacgt ttggagctaa cattacattg tcacctattt caattttaca tacatctaaa
     2461 aaaatacaat cataatttgc aaagaaattt tcgcctacat gtatgttata tccataatca
     2521 cacctaatat tttgttctac atttatttgc ttgccaactg aaccaaatag ttgtcttaaa
     2581 atatcttctc ttttttcata ttcatcctct aaagtattat taaacaatct agttaatttt
     2641 ttacaatact ctctttcttt tactaacaat tcatcatttg catagtatcc tttcccagac
     2701 aacatttttt ctttttcagt catatagttt actccttttt gttataattg tatctaaagc
     2761 aaaataaata ttcctgtgga aaatctaaat atattctgtc acctttctta aatctcattt
     2821 tacttttttc caattctatt tgaataggta cacattcgtt agataaatca gtttttctaa
     2881 catatatagt atatgtaaaa ggattttcta caatgttaat caattcgaaa cataactttt
     2941 catttaaatc ttcattagaa tccaagacct taatatgatg ctccctgatt cccacatatt
     3001 ctatattatc acctatttct ctatttaatg tcaactcgca tccccagtct gtagcataaa
     3061 tagtattttt atccagtcta tttaatttgg atatattttt acaccctgtt atcttagctt
     3121 ctataaggta ctttggagat tcaaagagct cttttttagg tctctttgga agaccttctc
     3181 ctttgttgta cactataata tcatcacaaa ctcggtaagc ttcttcaata tcatgagtaa
     3241 caaatagtat atctcccttg taatctttta acatattcat aagttctttt tccatattgc
     3301 ttcttaaatg atggtccaat gctgagaaag gttcatctaa aagtaatata tctggagatg
     3361 ttgccaatgc tctagctagt gctacccttt gttgttgacc accagataat tgccaagggt
     3421 atctcccctc aaacccattt aatttaagta tatctaagta ccttgctact atttcctttt
     3481 tttcactctt acttagtttt aaaagcccaa gttctatatt ttgacttaca gtcatatgtg
     3541 gaaacaaagc atagttttga aataaaaatc ctacctttct atcttgtgtt gataaattta
     3601 tcttcttttc agaatcaaat agaactctat catttaatac aattttacct cttgttggtt
     3661 tctcaagccc tgctatacat tttaatgtca tactttttcc agaaccagat tctcccaaaa
     3721 accccagagt acctttttct tgtttaattt ctacctttag tttaaaagag gataaatctt
     3781 tttcaatatc cacgtataag ctcaactatc cacacctctt tcctataatt ttctgctgaa
     3841 attccgacca ataatttagt aataaaatca ttgctataga tattgctaca ataatcataa
     3901 cccacatcat agctttattc atatctccgc cttcaacagc aaaaaatata gctattggca
     3961 tagtttgagt ttttccaggt atatttccag ctatcataag tgtagcacca aattctccaa
     4021 gagctctggc aaacgacagc accaatccac caattattcc aggccatgct aatggaactg
     4081 caatcttaaa aaatactttc cattcattaa gacctaatgt tctagcagct gacaacatat
     4141 tattatcaat ctgttcaaaa gctgaccttg aagttctata catcatagga aaagacacca
     4201 ctactgctga aattacagtt gctgtccaac taaatattaa agtcctatcg aaatttaata
     4261 aaaactttcc tataaatcca ttcttcccac atagtaataa taaaaagaaa cctacaactg
     4321 ttggtggcaa aattagtgga agtgtaaata gtccatctat aagacccttc cacttacctc
     4381 tatagttagc cataatatat gacacaaata ttcctattac aaaagttatt attgttgaca
     4441 aaatagatgt cttaagtgat atccataagg gtgaccaatc tgttcccatc tttccctcct
     4501 taattttaaa tggaaatagt gaaactaata actctattaa tttcactatt tccattttat
     4561 tataatacac aattattttc aattttcatt tatttatata taatttatac ttaattacac
     4621 ataatttatt tctaagttta ttctactttt ttatatccaa attcttcaaa aatcttttgt
     4681 cctgactcac ttaataaaaa ttcttcaaat ttcttagcag catctacgtt tttactagct
     4741 ttaattactg aaactggata tgtaataggc gaatgagttt tttcgtctgt tttttcaact
     4801 acttttatct tatcattatt gacagtatca ctgaagtaaa cgaatccaac atcagcattt
     4861 cctgattgca cccatgctaa aacttctttt acatcttttg caaatactag cttatctttt
     4921 aacttatctt ttaaatttaa attagttaac acctcatctg catacttacc agctggaaca
     4981 ctttcagctt caccaacagc aattttcttc actttatctg tagtcaaatc ttccatacct
     5041 gatacactac tgtcagcaga agaaataaga actaaatcat tttttactaa atctttcata
     5101 gtatcagaaa ctaataactt ctcttcatcc aaagctttca tttgtttttg acctgctgaa
     5161 ataaataaat cacaaggtgc tccttgttct atttgttgtt gtaatgagcc tgatgctcca
     5221 tagttaactg taagttttac atttgaatca acttttttat attcttcttc aatctttgcc
     5281 attgcttctt ttaaacttgc agcagccgat atatttaact ctactgaatc actactttta
     5341 gttgtttttt cttgttttcc atcatctttt ttgtcttcat tactattgca cccaactgtc
     5401 cccaaagtta aacatgcaac taatcctaat attcccaata tttttttcat aacaatctcc
     5461 ctttttgtaa atttgataca cattttaaca tgttttatta tgttttatca tgttttgtta
     5521 tatatagttt aattatatat acatgataat aaattttcaa gtaatttatt tacactactt
     5581 ttaaatattt tgctacattt tccttttttt aatgttaaaa taaccttata tggaggtgga
     5641 ttatggactc attatcatct ttgacacctg tcgaggtagc tgaattatta aagataacaa
     5701 aaaatactgt atatgaatta atcaaaagag gtgaacttcc ttcttataaa gtagggaaaa
     5761 aaataagagt tgatactaaa gatgttgaag aatatatcaa cagccaaaaa actggtaaag
     5821 taaaggatac acatttcaac aataaaaata tagatataaa taataatttc aaaattatta
     5881 tttctggtca agatgtaata ttagacattt tagctaggtc tgttgaaaaa aaattggatg
     5941 gaataagtac atttcgctct tatataggta gttataatgc tttgtatgag ttatataatg
     6001 gcagagtttc tatagcatca tcccatctat gggatttcga aacggatgaa tataatagca
     6061 cttttgttaa aaagctattg ccaggaatac catgtgtact tataaatcta gcttatagaa
     6121 tgcaaggttt ctatgttgct aaaggaaatc ctaaagagat aacaacctgg gaggatttaa
     6181 caaaaccaag tataaccatt gtaaataggg aaaaaggttc tggaactagg gttttactag
     6241 atggtaaact tagacttcta aactttaatg gtaaacatat aaaaggttat gataatgaag
     6301 aattatcaca tcttggagtt gcaagtactg tttctcgtgg aatagcagat gttggtttgg
     6361 gaaatgaaaa agctgcttta caagtaaata atatcgactt tattcctctt cacaaagagc
     6421 gctatgattt agttattaaa aaagaagact tacaaaatcc agtttaccaa actataatta
     6481 acataataaa ctctcctgag tttaaagctg aacttcaagg tcttggcgga tatgatttaa
     6541 ctgatactgg aaaaactata gcaaaagttt aagattaaaa tcgcaatcta ttttataaga
     6601 tttataattt ttcacaaaat ttataactta aacacgaaat aaattgcgat tttagtgtct
     6661 caaaaaattt atgtctttca ttttatcatc caatacaaaa tataatataa ttaattgtgc
     6721 aatcatatta tattaatata tatttacata atagtatttt tctttaatgt agattaacat
     6781 atgatatgtt ttaaacatca atccccttgc tttcttatat atatttggca acacatatga
     6841 gtttaataaa ttatatacaa tgttgctttc ttcttgtatt ttttcaacca acaagttatt
     6901 tataaaatta cctttctcat tttcaataat ctcactccaa tttatcttaa cttttaatat
     6961 atatcttccc actaggtata cacactctac aataaataat aaaaatacaa tgcagtcagt
     7021 acctgttgtc ttatataaat tacccgatac taatggcttt gcgaagaaat tataaaaatt
     7081 caaagtatca cccgtataat caaaaagtat taatagcact cctagaactc tcaatacttt
     7141 aatattcaac atgtttttat ctttattatt tttgtttttc atatatacta cctctctttt
     7201 ctttagattt gattgtaatc taatactaac tcttttattt gaggtataaa tgaatttaat
     7261 tggtagttat tttcattttt actagaaatt aattcacatt actaaacaaa acttatattt
     7321 aaacataaaa atagcctatc tatcttttaa taaatacaaa aataaataag ctactaatat
     7381 tcaattaact tttatcactt aaaacattac tatctataaa tttaaatatt ttattgaagt
     7441 atactgtact atcatgttca aatccatcaa catgaccaat accttctata agccataggt
     7501 cttttttatc atgtttaact aaatcataca ttttcttgct attttgataa ttacaaacag
     7561 tatcttttgt tccatgtata aacagtatgg gtacattaga tttctcaact gactcatatg
     7621 gttttacatc actgtaccaa aatccagatt taaacttatt atataaatct ccacaagtca
     7681 ccacataatt gattaatata tctggtattc gtttttctag tactcccatt ctaattgcat
     7741 ctttcatttc agaataagga gaatccagta tataaaaatc gaccttatca tcttttgaat
     7801 ttatctctga atgcatagca gctgtccctg cccccatgga aaatccatgc acacctaatc
     7861 tcccttcagg aaatttattt tttacaaatt taactagact atctaaatca tacctttcat
     7921 aaagaccaaa tgtgtaatta tctccaccac tattaccagt atttctttga ttataaacta
     7981 atacattata acctttatct aaatatctat atgctacctt taacatttca tagtaactac
     8041 ttccaattcc atgaacaagt atcatagtat ctcttgtctt tatatttgaa gttataaaaa
     8101 gactttcaag cttgtaatta ttagaacttt gtatcattaa ttcagatgtc ttgtagtttt
     8161 ttaatttctc cagtggttta tcttttctct cagaaaatat ttttactata tcttcgtttt
     8221 ttattaactg ctctaaacca actgaactat tatacactaa ttttccaaat atataagata
     8281 caattaatag gattaataga aacacaattg atataattat aaatttattt cttaaactaa
     8341 tacaattttt aaaactattt ttcatattta tttac
//
LOCUS       DAMJVG010000122         7977 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.127, whole genome shotgun sequence.
ACCESSION   DAMJVG010000122 DAMJVG010000000
VERSION     DAMJVG010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7977)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7977)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7977
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.127"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            1..75
                     /locus_tag="PC512_003437"
     tRNA            1..75
                     /locus_tag="PC512_003437"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:33..35,aa:Thr,seq:tgt)
     gene            90..174
                     /locus_tag="PC512_003438"
     tRNA            90..174
                     /locus_tag="PC512_003438"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:124..126,aa:Tyr,seq:gta)
     gene            184..267
                     /locus_tag="PC512_003439"
     tRNA            184..267
                     /locus_tag="PC512_003439"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:218..220,aa:Leu,seq:tag)
     gene            291..365
                     /locus_tag="PC512_003440"
     tRNA            291..365
                     /locus_tag="PC512_003440"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:323..325,aa:Gly,seq:gcc)
     gene            390..466
                     /locus_tag="PC512_003441"
     tRNA            390..466
                     /locus_tag="PC512_003441"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:424..426,aa:Arg,seq:tct)
     gene            476..551
                     /locus_tag="PC512_003442"
     tRNA            476..551
                     /locus_tag="PC512_003442"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:509..511,aa:Gln,seq:ttg)
     gene            560..635
                     /locus_tag="PC512_003443"
     tRNA            560..635
                     /locus_tag="PC512_003443"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:593..595,aa:Lys,seq:ttt)
     gene            638..726
                     /locus_tag="PC512_003444"
     tRNA            638..726
                     /locus_tag="PC512_003444"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:672..674,aa:Ser,seq:tga)
     gene            730..805
                     /locus_tag="PC512_003445"
     tRNA            730..805
                     /locus_tag="PC512_003445"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:763..765,aa:Phe,seq:gaa)
     gene            812..885
                     /locus_tag="PC512_003446"
     tRNA            812..885
                     /locus_tag="PC512_003446"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:846..848,aa:Met,seq:cat)
     gene            900..976
                     /locus_tag="PC512_003447"
     tRNA            900..976
                     /locus_tag="PC512_003447"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:934..936,aa:Ile,seq:cat)
     gene            994..1070
                     /locus_tag="PC512_003448"
     tRNA            994..1070
                     /locus_tag="PC512_003448"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1028..1030,aa:His,seq:gtg)
     gene            1079..1154
                     /locus_tag="PC512_003449"
     tRNA            1079..1154
                     /locus_tag="PC512_003449"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1112..1114,aa:Lys,seq:ttt)
     gene            1162..1235
                     /locus_tag="PC512_003450"
     tRNA            1162..1235
                     /locus_tag="PC512_003450"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1194..1196,aa:Cys,seq:gca)
     gene            1243..1319
                     /locus_tag="PC512_003451"
     tRNA            1243..1319
                     /locus_tag="PC512_003451"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1277..1279,aa:Arg,seq:acg)
     gene            1332..1407
                     /locus_tag="PC512_003452"
     tRNA            1332..1407
                     /locus_tag="PC512_003452"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1365..1367,aa:Val,seq:tac)
     gene            1483..1896
                     /locus_tag="PC512_003453"
     CDS             1483..1896
                     /locus_tag="PC512_003453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443153.1"
                     /translation="MYIVIGNEIVDSEELKIIIDKNSEFKVEKDLSKSTKREDVIAYQ
                     LSIDLNYLDSLINEQCNLASLSDEEKFDEYMTLSDELALDLEELMPKYTIINARAYKL
                     DEVDGIVKIILAVAYADLGHLKLSDVVKRLSRQVD"
     gene            2205..5636
                     /locus_tag="PC512_003454"
     CDS             2205..5636
                     /locus_tag="PC512_003454"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HDF2443154.1"
                     /translation="MLKKFNKILVANRGEIAIRIFRACSELGIKSVGIYSKEDKYGLF
                     RTKADESYLIGEGKGPIDAYLDMDGIIDLAKRKKVDAIHPGYGFLAENAEFARKCEEN
                     GITFIGPSSKVMNMMGDKINSKKIAKEVNVQTIPGVEKAIRSTEEAKEVANKIGYPVM
                     IKASNGGGGRGMRIVHREEDLELEYETACSESRKAFGEDIIFIEKYIADPKHIEVQIL
                     GDNYGNIVHLYERDCSVQRRHQKIIEYAPAFSLDDKVRKEICEDAVKLSKHVGYSNAG
                     TLEFLVDANGGHYFIEMNTRVQVEHTVTEMVTGIDIVQSQILIAQGYSLDSEEINIKS
                     QDDVEIRGYSIQCRITTEDPKNKFMPDTGKIQVYRTGSGFGIRLDGGNGFTGANISPH
                     YDSLLVKTISWDRTFQGAINKTIRSIKELRVRGVKTNVGFLVNVLNNPIFSNGKCSTK
                     FIDENPDLFEITESKDRGTKLLQFIGDVIVNDNACKEKPLFDALHDPRMDKDGSKSEG
                     SKILFDKLGKSAYIEKIKNDKKLLLTDTTMRDAHQSLLATRIRTYDLLKAAKPTEKYQ
                     KDLFSLEMWGGATYDVAYRFLKESPWRRLQKLREEIPSIMFQMLLRASNGVGYKNYPD
                     NVIEEFTKESARQGIDVFRIFDSLNWVENMKPSINTALETGKIVEATMCYTGDILDKT
                     KTKYNLEYYIKMAQELESLGADIIAIKDMSGLLKPYSAYTLVKELKKNVKAPIHLHTH
                     DTSGNGVATCLMASEAGVDIIDAALESMAGLTSQPSLNAIVEALKNTERDTGIDLFGY
                     DELGKYYKDLRKVYNKFESDLTNSCAEIYNFEIPGGQYTNLKPQADSLGLVNRFDEVK
                     EKYKEANEVVGDIIKVTPSSKVVGDLAIFMTKNKLDKDNIIEEGKNLSFPDSVVDYCK
                     GMIGQPEGGIPKDLQEVVLKGEEAITVRPGSLLPAEDFDEIAKYLNEKYDINANIRNV
                     ISYALYPKVYEDYIKHLQHYNDISKLESDVFFYGLNKNEECEVEIEEGKVLTIRLVEI
                     GEVKENGFRTIGFELNGMVREVEIKDKNFSGKINNVEKADMNDPLQIGASIPGKVIKI
                     MVKEEDEVKANQPLIVIEAMKMETIIVAKTDGVIKSIKVKEDDMVEDKQLLMIMK"
     gene            5878..7806
                     /locus_tag="PC512_003455"
     CDS             5878..7806
                     /locus_tag="PC512_003455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HDF2443155.1"
                     /translation="MKVYDSKMLRNVAVLGHSGCGKTNLIETIAYTANTNKIPKLTDK
                     VNMTYSMGLIPIEYNDYKFNLLDTPGYFDFSGDVVSSLRASDAAIIVIDATAPIQVGT
                     EKSLELTESIPKIMFINKIDNEKARYKDAIAMLREKYNNKIVPMISPIYKDKNFVKLH
                     NVFENIDDLEGEFKEQAMSVKEALMELIAETDDQILDKYFNGEELTTEEIQKGIIIGI
                     QRGDIIPVICGSTINNIGTKEILDTISSYLEPIFTEESKPFRGLVFKTMVDPFVGKMS
                     YIKITEGVLSKDKDVFNINKNVKEKIANIYTLRNSELVEIEKAKAGDIVVITKVNSLK
                     TGDTISADKDAEALEKIDFPKPQIYYAVTPKNKGDEEKVASVLNKLVEEDPTLHWYRN
                     TETKQALLGGQGELHIKTIKNKMKDKFGVDVELNDLKVPYRETIKGTADVQGKHKKQS
                     GGHGQYGDVKIRFERCESDFEFTEEIFGGSVPKQYIPAVEKGLKDSMQKGILAGYPVT
                     NIKATLYDGSYHDVDSSEMAFKMAASAAFKKGMEEAHPILLEPIMKLKITVPEEYMGD
                     VMGDINKRRGKIFGMEPDDKGKQIIFAEAPQAETFKYAIDLRAMTQGRGYFEMELERY
                     GEVPSQFAEKIIGLATAK"
BASE COUNT         3128 a         1008 c         1595 g         2246 t
ORIGIN      
        1 gctggtgtgg ctcaacggta gagcagctga cttgtaatca gcaggttgta ggttcgattc
       61 ctatcaccag ctccatataa aattaatacg gaggatttcc cgagcggcca aagggggcag
      121 actgtaaatc tgttgtcatc gacttcggtg gttcgaatcc accatcctcc accaaaaaaa
      181 tgcgcggatg tggcggaatt ggcagacgca ctagacttag gatctagcgc cattggcgtg
      241 ggggttcgac tcccttcatc cgcaccattt ttatttaatt taataaacga gcgggaatag
      301 ttcagtggta gagcgcaacc ttgccaaggt tgaagtcgcg agttcgaatc tcgtttcccg
      361 ctccaaattt tatgtttatg ttgtaatgtg ggtgcatagc tcagctggat agagcaacgc
      421 ccttctaagg cgtgtgtccg gggttcgaat ccctgtgcgc tcaccacata tatattgggg
      481 attagccaag tcggtaaggc acatgacttt gactcatgta tgcgtaggtt cgagtcctgc
      541 atccccagcc aaacagtatg gtctattagc tcagtcggta gagcacctga cttttaatca
      601 gggtgtcccg cgttcgagtc gcggatagat caccaatgga gaggtgtccg agtggtttaa
      661 ggagctggtc ttgaaaacca gtgacttcga aaggggccgt gggttcgaat cccaccctct
      721 ccgccaaatg cccagatagc tcagtcggta gagcagggga ctgaaaatcc ccgtgtcggt
      781 ggttcgattc cgcctctggg caccaaaatg tggcggtata gcttagttgg ctagagcgtt
      841 cggttcatac ccgaaaggtc ataggttcga ctcctattac cgctactaaa atttaatgtg
      901 ggccattagc tcagttggtt agagcgcccg gctcataacc ggtaggtctg gggttcgagt
      961 ccctgatggc ccaccacatt aaattaactt atggtgggta tagctcagtt ggttagagcg
     1021 ccagattgtg gctctggagg tcgtgagttc gactctcatt atccacccca acttatatgg
     1081 tctattagct cagtcggtag agcacctgac ttttaatcag ggtgtcccgc gttcgagtcg
     1141 cggatagatc accaaaaagg cggcgacata gccaagtggt aaggcagtgg actgcaactc
     1201 cttgatcccc agttcgaatc tgggtgtcgc ctccaataaa atgcgctcat agctcaactg
     1261 gatagagtgt ctgactacga atcagaaggt taggggttcg agtccctttg ggcgcaccat
     1321 atgaatagcg agggattata gctcagctgg gagagcacct gccttacaag cagggggtca
     1381 caggttcgag ccctgttaat cccaccagtg caaacctcta gtaaaactac tagaggtttt
     1441 atttttgatt gaaaaagttt ttatatttag gaggtaaaaa atttgtatat agtaatagga
     1501 aatgaaatag ttgatagtga agaacttaaa ataattatag ataaaaatag tgaatttaaa
     1561 gttgaaaaag atttaagtaa aagcacaaaa agagaagatg taatagcata tcagttaagt
     1621 atagatttaa attacctaga ttctcttata aatgagcaat gtaatttagc cagtctatct
     1681 gatgaagaga aatttgatga atatatgact ttgtctgatg aacttgcact ggatttagaa
     1741 gagttaatgc caaaatatac aataataaat gctagagcat ataaattaga cgaggtagat
     1801 ggaattgtaa aaataatact agctgtagcg tatgcagatt tagggcactt aaaactttct
     1861 gatgtagtaa agaggctatc tagacaagta gattaggata tgaatatgaa ctatattaaa
     1921 aaaatgtata aaatcttacg taaagatgaa aataattatg taaacataga aaaaaacagt
     1981 ataaaatcaa gtcaattgta gaaattttca cataaattca tctgaaattc tgtaaaaaat
     2041 gccttaattt taatgaggta aatcgagttt acacagtcta aaaattactt atatttataa
     2101 atttatctta ttaattaagg aactttctta aacatcttca aaaataaagt attttagtct
     2161 ataatcttta atattacaca aacaataaag gagaagaata gagtatgctt aaaaagttta
     2221 ataaaatact agtggctaat agaggcgaaa tagctataag aatatttaga gcctgttcag
     2281 aattggggat aaaaagtgtt ggtatataca gtaaggaaga taagtatgga ttgtttagaa
     2341 caaaagcgga tgaatcatat ttgataggag aaggtaaagg gccaatagat gcatatttag
     2401 atatggatgg aataatagac ctagcaaaga gaaaaaaagt tgatgctata catccaggat
     2461 atggttttct agcggagaat gcagaatttg ctcgtaaatg tgaagagaat ggaattactt
     2521 ttataggacc atcatctaag gtaatgaata tgatggggga taagattaac tctaaaaaaa
     2581 tcgcaaaaga agttaatgtt caaactatac caggagtaga aaaagcaata agaagtactg
     2641 aagaagcaaa ggaagttgca aacaaaatag gatatcctgt tatgataaaa gcatctaatg
     2701 gcggtggcgg tagaggtatg agaattgtac atcgcgaaga agacttagag cttgaatatg
     2761 aaactgcttg tagtgaatca agaaaagctt ttggagaaga tattatattt atagaaaaat
     2821 atatagctga tccaaaacat atagaagttc aaatattagg tgataattat ggaaatatag
     2881 ttcacttata tgaaagagat tgttcagttc aaagaagaca tcaaaaaata atagaatatg
     2941 caccagcttt ttcgttagat gataaagtaa gaaaagagat atgtgaagat gcagttaagt
     3001 tatcaaaaca tgtgggttat tctaatgcgg gaacattaga atttttagta gatgcaaatg
     3061 gtgggcatta ttttatagag atgaacacaa gagtacaggt tgaacatact gtaacagaga
     3121 tggttacagg aatagatata gttcaaagtc aaatactaat agcccaaggt tacagcttag
     3181 atagtgaaga aattaatata aaatcacaag atgatgtgga aataagaggt tactctatcc
     3241 aatgtagaat aactacagaa gaccctaaga ataaattcat gcctgataca ggtaaaattc
     3301 aagtttatag aactggttca ggatttggta taagactaga tggaggaaat ggatttacag
     3361 gggcaaacat aagtcctcat tatgatagtt tattggttaa gacaatatct tgggatagaa
     3421 cattccaagg agcaataaat aaaactataa gatctataaa agaacttaga gttagaggtg
     3481 ttaaaactaa tgtaggattc ctagttaatg ttttaaataa tcctatattc tcaaatggta
     3541 aatgtagtac taagtttata gatgaaaatc cagatttatt tgaaataaca gaaagtaaag
     3601 acagaggaac aaaattactt caatttatag gagatgtaat tgtaaatgat aatgcttgta
     3661 aagaaaaacc attatttgat gcattacatg acccaagaat ggataaggat ggttcaaaat
     3721 cagaaggaag taaaatactt ttcgataagt taggtaaatc tgcatatata gaaaagataa
     3781 aaaatgataa gaaattacta ttaacagata caacaatgag agatgcacat caatcattat
     3841 tagcaacaag aataagaaca tatgacttat taaaagctgc taagccaaca gaaaaatatc
     3901 aaaaggattt attctcactt gaaatgtggg gaggagctac ttatgatgtt gcatatagat
     3961 ttttaaaaga atctccttgg cgtagattac aaaagctaag agaagaaata ccaagcataa
     4021 tgttccaaat gttgcttaga gcatcaaatg gagttggata taaaaactat ccagataatg
     4081 taatagaaga atttacaaaa gaatctgcta gacaaggtat agatgtattt agaatatttg
     4141 attcattaaa ctgggttgaa aatatgaaac catctattaa tacagcttta gaaactggaa
     4201 aaattgttga agcaactatg tgttatacag gtgatatact agataagact aaaactaaat
     4261 acaatctaga atattatatt aaaatggcac aagaattaga aagcttggga gcagatataa
     4321 tagcaataaa agatatgtca ggtcttctta aaccatattc agcttacaca ctagttaaag
     4381 agttaaagaa aaatgtaaaa gcaccaatac atttacacac tcatgataca agtggaaatg
     4441 gtgtagcaac ttgtttaatg gcgtcagaag ctggagtaga cataattgat gctgcattag
     4501 aatctatggc aggacttaca agtcagccat cacttaatgc tatagtagag gcacttaaga
     4561 atacagagag agatacagga atagatttat ttggatatga tgagttagga aaatattata
     4621 aggatttaag aaaagtttat aataaatttg aaagtgattt aactaattct tgtgcagaaa
     4681 tatataattt tgaaatacca ggaggccaat atacaaactt aaaacctcaa gctgatagtt
     4741 taggattagt taatagattt gatgaagtta aagaaaaata taaagaagct aatgaagttg
     4801 taggagatat aataaaagta actccatctt caaaagttgt aggagactta gctatcttta
     4861 tgactaaaaa taaattagat aaagataata taatagaaga aggtaaaaat ttatcattcc
     4921 cagattctgt tgtggattac tgtaaaggta tgattggtca accagaaggt ggaataccaa
     4981 aagatttaca agaggtagtt ctaaaaggtg aagaagctat aacagtaaga ccaggttcat
     5041 tattaccagc agaagatttt gatgaaatag ctaaatatct aaatgaaaag tatgatataa
     5101 atgctaatat aagaaatgtt ataagttatg ctttatatcc aaaagtatat gaagattata
     5161 tcaaacatct acaacattat aatgatatat ctaaacttga aagtgatgta ttcttctatg
     5221 gattaaataa aaatgaagaa tgtgaagtag aaatagaaga aggtaaggta ttaacaataa
     5281 gattagttga aattggtgaa gttaaggaaa atggatttag aactatagga tttgagttaa
     5341 atggaatggt tagagaagta gaaataaaag ataagaattt ctctggaaaa attaataatg
     5401 ttgaaaaagc tgatatgaat gaccctcttc aaattggagc aagcatacca ggaaaagtta
     5461 taaaaataat ggttaaagaa gaagatgaag taaaagcaaa tcaaccatta atcgttatag
     5521 aggctatgaa gatggaaact ataatagttg ctaagactga tggagtaatt aagtcaatca
     5581 aagtaaaaga agatgatatg gttgaagata aacaattatt aatgataatg aagtaattta
     5641 attaaaataa attaaaaagc actctgaaat gtttaataaa aaatgtttta gagtgttttt
     5701 atttatttta attaaatatt tgttaaaaaa aagaggacaa ttacctccag atgtagaaat
     5761 aaagctagta aggaaaatgt tatctaaaaa ttctaaatat agtaaatatt ttccataata
     5821 tttcttagga aataacagca aagataaaat acataaattt aaaaggtggg tgcttatatg
     5881 aaggtttatg atagtaaaat gttgagaaat gtagcggtat taggacatag cggatgtgga
     5941 aaaacaaatc taatcgaaac tatagcttac acagcaaaca ctaataagat acctaaatta
     6001 acagacaagg taaatatgac ttatagcatg ggattaatac ctatagagta taatgattat
     6061 aagtttaact tattggatac cccaggatat tttgacttta gcggagacgt tgtgtcatct
     6121 cttagagcaa gtgatgcagc aataatagta atagatgcaa cagcgcctat tcaagttggt
     6181 acagagaaat cattagaact aactgagagt attcctaaga taatgtttat aaataaaata
     6241 gataatgaaa aggcaagata caaagatgca atagcaatgt taagagaaaa atacaataat
     6301 aagatagttc ctatgataag tcctatatac aaagataaaa actttgtaaa gttacataat
     6361 gtttttgaaa acatagatga tttagaaggt gaatttaagg aacaagctat gagtgttaaa
     6421 gaagcattaa tggaacttat agcagaaact gatgaccaaa tattagataa atattttaat
     6481 ggagaagaac taactacaga agagatacaa aaaggtatta ttataggtat acaaagaggt
     6541 gatattatac ctgtaatatg tggttcaact ataaataata taggcacaaa ggaaatatta
     6601 gatacaatat caagttattt agaacctatc tttacagagg aaagcaaacc atttagggga
     6661 ttagtattta aaactatggt tgacccattt gttggaaaga tgtcatatat aaaaattact
     6721 gagggtgtac tttctaagga taaagatgtt tttaatataa ataaaaatgt aaaagaaaaa
     6781 atagctaata tatatacatt gagaaatagt gaattagtag aaatagaaaa agctaaagct
     6841 ggtgatatag tagttataac taaagttaat tctctaaaaa caggagacac tatatctgca
     6901 gataaagatg cagaagcttt agaaaagata gattttccta aaccacaaat atattatgca
     6961 gtaactccta agaataaagg tgatgaagaa aaagtagcat ctgtattaaa taaactagta
     7021 gaagaggacc ctacattaca ttggtataga aatacagaga caaaacaagc acttttagga
     7081 ggtcaaggag aacttcatat aaaaacaatt aaaaataaaa tgaaagataa gtttggtgtt
     7141 gatgttgaat tgaatgacct taaagttcct tatagagaaa ctataaaagg aacagctgat
     7201 gtacaaggaa aacataaaaa gcaatcaggt ggtcatggtc aatatggaga cgtaaaaata
     7261 agatttgaaa gatgtgaatc tgattttgaa tttacagaag aaatatttgg tggttctgta
     7321 ccaaaacaat atataccagc agttgaaaaa ggtttaaaag actctatgca aaaaggtata
     7381 ttagcaggat atcctgttac aaacataaaa gctacgcttt atgatggttc ataccatgat
     7441 gtagactctt ctgaaatggc ctttaagatg gcagcaagtg cagcctttaa aaaaggtatg
     7501 gaagaagcac acccaatact actagaacct ataatgaaac ttaagataac tgttccagaa
     7561 gaatatatgg gagatgtcat gggtgatata aataagagaa gaggaaaaat atttggaatg
     7621 gaaccagatg acaaagggaa acaaataata tttgcagaag ctccacaagc agagacattt
     7681 aaatatgcaa tagatttaag agcaatgaca caaggtagag gatactttga aatggaatta
     7741 gagagatatg gagaggttcc atcacagttt gcagaaaaaa taattgggtt agctactgca
     7801 aagtaatgaa caaaataaat agaaaaataa ttaatatata ttattaaaaa tatttttagg
     7861 gttttaacta ggtataggtt tatgttaggt aaacttatac ctagttttta tacatttttg
     7921 atgaataaaa aaatatataa tactttctta aatattttaa taaaaagaaa gtatttt
//
LOCUS       DAMJVG010000123         7968 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.128, whole genome shotgun sequence.
ACCESSION   DAMJVG010000123 DAMJVG010000000
VERSION     DAMJVG010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7968)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7968)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7968
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.128"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            169..1620
                     /locus_tag="PC512_003456"
     CDS             169..1620
                     /locus_tag="PC512_003456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine:cation symporter family protein"
                     /protein_id="HDF2443156.1"
                     /translation="MDFFNGILTSINNAVVFVNNYLWSYILIIMLVVIGIYFTIKTNF
                     VQFRYFIEMFRLLGDGTANKNAKKEGKISSFQAFCISTSSRVGTGNIAGIAIAVVAGG
                     PGAVFWMWLIALIGSASSFVESTLAQIYKVKDGQAFRGGPAYYMEQGLNKKWMGILFS
                     ILITICYGFVFNAVQANTVSLAFNNAFGISKMAMGIGLGILTAIVIFGGVHRVAKVSE
                     IIVPVFAGLYILVALAIVVMNITEIPSVIALIVESAFDFKGMAIGTFMGVVMTGVKRG
                     LFSNEAGMGSAPNAAATAHVTHPVKQGLIQSLGVFTDTIIICSCTAFMVLLYSGYSSS
                     GATGIELAQEALTHHIGPVGNIFIAVCIFLFAFSSIVGNYYYGESNMEFMSGSKTKLN
                     VFRVFVVGMVLFGSLTQVDVVWNLADLFMALMAIINLIAIALLGKYAFIALKDYTSQK
                     KSGIKDPVFIADEIEGLEKVSEWHRELSEEHLG"
     gene            complement(1818..2459)
                     /locus_tag="PC512_003457"
     CDS             complement(1818..2459)
                     /locus_tag="PC512_003457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007491147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HDF2443157.1"
                     /translation="MTDNYIFDSYNNLVDGLSAYLGEGYEFILYKFNGVHYSINKIAN
                     GKYNTVKEGDIITDFDLALINKLENDADGDFISYFNRNKLGEPLKSTDIVIRGVDNKI
                     IGLLCIHFYLNTPLTRIIGSYIPEHNAMQSAPVLENIVEDTDEVILKSYQDAKVIVEN
                     DSNISSNDKNKSIVSILNESGIFKIKDSVVKVADLMGLSKNTIYMHLRNLNKN"
     gene            2933..4312
                     /locus_tag="PC512_003458"
     CDS             2933..4312
                     /locus_tag="PC512_003458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016290023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDF2443158.1"
                     /translation="MAQDKIVVEILENIGGKENIKEVAHCMTRLRIKVCDSSQVNQEK
                     LKKIKGVLGLVLKGEQYQIVIGPNVSQVYNTLNEVIGIIPEKDSKKTISEGKQNSIAK
                     ILDTIAGIFNPIVPALAGAGLIKAILALLVASKFLSADSETYIILNTISDGVFSFLPF
                     MLAYSAAKIFKMNTYVAVAIAGAMLHPNFINLIQQGLTKISFIGIPMSLIQYNGSVFP
                     IVLTIWFASYIEKGVDKITPKALKIILVPALTILFAAPIALIIIGPIAQMLGNYIAGG
                     ASILFERGGIFAGLIYGGIYSFMVVTGLHHGMVPVLVDGITRYGFNYISPVSGSSNMA
                     QAGSAFGVWLKAKDKDLKAVAATATISALTGVTEPAIYGVNLRLKKPFLCAAIGGAAG
                     GGFAAYFQCKAFAMGGPSFLTLPMFIGEGGHVGLVAIAFTIAFIVSAIATYIVGFEEE
                     VTADSHANL"
     gene            4356..5090
                     /locus_tag="PC512_003459"
     CDS             4356..5090
                     /locus_tag="PC512_003459"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010990049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HDF2443159.1"
                     /translation="MKIYLTKDYEEMSQVAAQMVLKYMYSNDNKRINLSITAGQTPKR
                     TYEILSEFVKNKPYFENVHYYNFDEIPIKGEKVGVTIRNLTNMYFREAQIPEERIHVL
                     DENNYQGFDRKIEADGGIDMVLMGLGWDGHFCGNLSGTVNSFDEETRAVSTYITDDMA
                     KLLTKSVGGNPEKLFDYYVTYGPKTIMHCKNIIMIVNGKHKAQILKQTLFGPLDLLCP
                     SSLLRLHPNFTLIVDEEAASEIKDLI"
     gene            5179..6378
                     /locus_tag="PC512_003460"
     CDS             5179..6378
                     /locus_tag="PC512_003460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006875852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDF2443160.1"
                     /translation="MYNHMKKVFQGLEGGLFSSVEKADVGDSYQKLGEQGVSLMGWAD
                     PFFPDYCIPRHILDAATLAISSNMSTHYTAPVGNDLLKIEIAEKLKEVNNLDVDFKRN
                     ILITPGSDSGLYYSMLPFINEGDEVLIPTPCYPNNIQNTKLMGGVPIFVELKESDGYQ
                     IDITEFEKRLTNKTKLVVLTHPNNPTTTIFNKESLEKLAKFIIDNDLILICDQAFEDF
                     TFENELITPASLEGMFERTVTIFSTSKGMGLSGFRVAYMVCSDKLMDKYYGAAVTVLG
                     ATNTVAQMSTIEAFKDRSFMEDFERVFDKRRQEAYKIINEIPNVSMQMPESGFLGWIN
                     VSKLGTSSEIQKYLVDEAKVCINDGINYGPGGEGHLRIILGSYKDDSKVIGALNRIKD
                     ALIKKQQ"
     gene            6402..6884
                     /locus_tag="PC512_003461"
     CDS             6402..6884
                     /locus_tag="PC512_003461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015529974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2443161.1"
                     /translation="MLSIFKSKKNDNKLKAFASGKVIPIEDVDDNVFSSKMLGDGIAI
                     YPTNEYVVAPCDAEVNIIMKDTKHAVGIKLFNGMEILFHVGIDTVSMNGEGFEIFVSP
                     GDKIKRGDKLISFNSKLIKEEGLQDVVIMVVTNSEQYKNIKYHIGLEAVIDDTIIAEI
                     "
     gene            complement(7202..7799)
                     /locus_tag="PC512_003462"
                     /pseudo
     CDS             complement(7202..7799)
                     /locus_tag="PC512_003462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816433.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2949 a          912 c         1352 g         2755 t
ORIGIN      
        1 ttgaatataa aactgcaata tattaaaaaa attattcatt ttaaaccttg taatttgatt
       61 ttataaatat tataattaaa ttaatgaatt tttaacaagg aattattcat ttttttgatt
      121 ttaagattta ttgagaaaac aaaactaaat aggggggtaa ttaatataat ggattttttc
      181 aatggtattt taacgagtat taacaatgca gtagtatttg taaacaatta cttatggtcg
      241 tatatcttaa ttataatgtt agttgtaatt ggtatttact ttactattaa aacaaatttt
      301 gtacaattca gatattttat agaaatgttt agacttctgg gtgatggtac agcgaataaa
      361 aatgcaaaaa aggaaggaaa aatctcttca tttcaagcat tttgtataag tacatcttca
      421 agagttggaa ctggaaatat agctggaata gcaattgcag tggtagcagg aggacctggt
      481 gctgtatttt ggatgtggct tatagcatta attggttctg catcaagctt tgttgagagt
      541 acattagctc agatttacaa agtgaaagat ggtcaagctt ttagaggtgg accagcgtat
      601 tatatggaac aaggtctaaa taaaaaatgg atgggtattt tattctcaat acttataact
      661 atatgttatg gttttgtatt taatgcagtt caagcaaata ctgtttcact tgcatttaat
      721 aatgcatttg gaataagtaa aatggctatg ggaataggtc ttggaatttt aactgcaata
      781 gttatttttg gtggagtgca tagagttgca aaagtttctg aaataatagt tcctgtattt
      841 gcaggattat atatattagt tgctttggct atagttgtaa tgaatataac agagatacca
      901 agtgttatag cattgatagt tgaaagtgca tttgatttta aaggaatggc gattggtaca
      961 tttatgggag ttgtaatgac tggagtgaag agaggtctat tttctaatga agcaggtatg
     1021 ggtagtgctc ctaatgctgc tgcaacagca catgtaactc atcctgtaaa acaaggttta
     1081 attcaatctt taggtgtttt tacagatact ataataatat gtagttgtac agcattcatg
     1141 gtattattat attcaggtta tagtagtagt ggagcaactg gaattgaatt agctcaagaa
     1201 gctttaactc atcatatagg accagttgga aatatattta tagcagtttg tatattcttg
     1261 tttgcattta gttctatagt tggtaattac tattatggtg aatcaaatat ggagtttatg
     1321 agtggaagta agactaaact taatgtattt agagtttttg ttgtaggtat ggttttattt
     1381 ggttcactta ctcaagtgga tgtagtttgg aatcttgcag acttatttat ggcattgatg
     1441 gcgataataa acttaatagc aatagcactt ttaggaaaat atgcatttat tgctttaaaa
     1501 gattatacaa gtcaaaaaaa atcaggaata aaagaccctg tgtttattgc agatgaaata
     1561 gaaggcctag aaaaggtatc agagtggcat agggaattat ctgaggaaca tttaggataa
     1621 aaaatagtat aaaattataa aaccattttg aaagactaga gtatgtatat actttatatg
     1681 aatataatat tgaattaatt tatattactg gaatttttaa ttccagtaat atttttttaa
     1741 ttacaaggat attatgatga cttaaagact gtggaaaact cttttttagt tttcattatt
     1801 aatattaatt gacaaattta gtttttattt aaatttctta agtgcatata aatcgtattt
     1861 tttgataatc ccattaagtc tgcaacttta acaacagaat ccttaatttt aaaaatacca
     1921 ctttcattta aaatagaaac aatagattta tttttatcat tgctagatat attagaatca
     1981 ttttcaacaa ttacctttgc atcttggtat gattttaaaa ttacttcatc agtatcttct
     2041 acgatatttt ctaaaacagg agcactttgc atagcattat gttccggaat atatgaacca
     2101 attattcttg ttagtggtgt attaagataa aaatgtatgc agagtagacc gattatttta
     2161 ttatcaactc cccttatcac tatatctgtt gattttaaag gttcacctag tttgtttcta
     2221 ttaaaataac tgataaaatc tccatcagca tcattttcga gtttattaat gagtgccaaa
     2281 tcaaaatcag ttataatatc tccttctttt acagtattat atttaccatt agctatttta
     2341 tttattgaat agtgtactcc attaaattta tataaaataa actcgtatcc ttctcctaaa
     2401 tacgcagata atccatccac tagattgtta taagaatcga aaatatagtt atcagtcatg
     2461 ttaaaagtca tatgttacct cctaagaaat atcttaatat catattaaca tataaaatga
     2521 atttaataaa atatatttca gtgaaataat aaatataatg aaaaaaaaac tattgactga
     2581 aaaatatttc agtgatatta ttaaaataca gtaaggcaaa cgtattattg acagaatata
     2641 taaaatgtta aaaatagtat ctaggaatta aacaaattaa aggactagtg atttgaattt
     2701 ttttagtata atatgtgact tccaattaat atttattaaa caccaataaa attgtaaata
     2761 tgcttaatga tatactttag cgatgaagtg aaaatatttt atttttatga ttaacctata
     2821 ggaattaatt tagcatactg tttagctagt aaatctaaat aaattttagc tttagctgat
     2881 atcatgttga ataaagtttc tattggattt tgtataacaa aggagtgggg agatggcaca
     2941 agataaaatt gtggttgaaa ttttagaaaa cattggtggt aaggaaaata ttaaggaagt
     3001 agcacattgt atgactagac tgagaataaa ggtatgtgat agttctcagg taaatcagga
     3061 aaaactaaag aaaataaaag gtgtactagg tcttgtatta aaaggtgagc aatatcaaat
     3121 tgttataggt cctaatgtat cacaagtgta taatactctt aatgaagtta taggaattat
     3181 acctgagaag gatagtaaaa aaacaatatc tgaaggtaaa caaaatagta ttgcaaaaat
     3241 attagatact attgcaggta tttttaatcc tatagttcca gcattagcgg gtgcaggtct
     3301 aataaaagct atattagcat tactagtagc atcaaagttt ttatctgcag atagtgaaac
     3361 ctatataata ttaaatacaa tatctgatgg tgtattttca tttttaccat ttatgttagc
     3421 ttactcagca gctaaaatat ttaaaatgaa tacttatgtt gctgtagcaa tagcaggagc
     3481 aatgctacat cctaatttca ttaatttaat tcaacaaggc ttaactaaaa tatcttttat
     3541 cggtattccg atgtcactaa tccagtataa cggaagtgta tttccgatag tactaactat
     3601 ttggtttgca tcgtatatag aaaaaggagt agataaaata acaccaaagg cacttaagat
     3661 aatattagta cctgcattga ctattttatt tgcagctcct atagcattaa ttattattgg
     3721 accaatagct caaatgctag gaaactatat agccggtgga gcaagtatcc tatttgaaag
     3781 aggaggaata tttgcagggt taatttacgg aggaatttat tcattcatgg tagtaacagg
     3841 attacatcat ggtatggttc ctgtattagt agatggaata acaagatatg gatttaacta
     3901 tataagtcct gtgtcaggta gttcaaatat ggctcaagca ggatctgcat ttggagtatg
     3961 gttaaaagca aaagataaag atttgaaggc tgtagcagct acagctacca tatcagcatt
     4021 aactggagtt accgaacctg caatatatgg tgttaattta agattaaaga aaccgttttt
     4081 atgcgctgct ataggtggtg cagcaggagg tggatttgct gcatatttcc aatgtaaagc
     4141 atttgctatg ggaggtccat cgtttttaac tcttcctatg tttataggag aaggtggaca
     4201 tgtaggattg gtagcaatag catttacaat agcatttata gtatctgcaa tagctaccta
     4261 tatagtagga tttgaagaag aggtaacagc agattcacac gctaacttat aataaagaga
     4321 aattatttaa catatcaaaa aggagattaa ttactatgaa aatttattta actaaagatt
     4381 atgaagaaat gagccaagtg gcagcacaaa tggtgttaaa gtatatgtac agcaatgata
     4441 ataaaagaat aaacctttct ataacagcag gtcaaacacc aaaaagaaca tacgaaatat
     4501 taagtgaatt tgttaagaat aaaccttatt ttgaaaatgt acattattat aactttgatg
     4561 aaataccaat aaaaggcgaa aaagttggag ttactataag aaatttaact aatatgtact
     4621 ttagagaagc tcaaatacca gaagaaagaa tacatgtgtt agatgaaaat aattatcaag
     4681 gctttgatag aaagatagaa gccgatggtg gaatagacat ggtattaatg ggattaggtt
     4741 gggatggaca cttctgtgga aatcttagtg gtacagtcaa ctcttttgat gaagagacaa
     4801 gagctgtttc aacttatata acagatgata tggctaaact attaacaaaa tctgtaggtg
     4861 gaaatccaga aaaattattt gattactatg tgacatatgg acctaaaaca ataatgcatt
     4921 gtaaaaatat aataatgata gtaaacggaa aacacaaagc tcaaatatta aagcaaacac
     4981 tatttggacc attagattta ttatgtccat catctttatt gagattacat cctaacttca
     5041 cattaatagt agatgaagaa gcagcatctg aaataaaaga tttaatataa ataagtaagg
     5101 aattaaaatt aaaaatgaat ttaggtgcaa agtaatattt tattttgcac ctttgcttta
     5161 ataaaaagga gaataaaaat gtataatcat atgaaaaaag tattccaagg attagagggt
     5221 gggttatttt caagtgtaga gaaagctgat gtaggcgatt cttatcaaaa attaggtgag
     5281 cagggtgtaa gtttaatggg atgggcagat ccatttttcc cagattactg tatacctaga
     5341 catatattag atgcagctac attagcgata tcaagtaata tgtcaactca ttatacagcg
     5401 cctgtaggta atgacttatt aaaaattgag atagcagaaa aattaaaaga agtaaataat
     5461 ttagatgttg attttaaaag aaatatatta ataactcctg ggtcagactc agggctttat
     5521 tactcaatgt taccgtttat aaatgaaggg gatgaggttc ttataccaac accatgctat
     5581 ccaaataata tacaaaatac taaattaatg ggaggagttc ctatatttgt agagttaaag
     5641 gaatcagatg gatatcaaat agatataaca gaatttgaga agagattaac taataagacg
     5701 aagttagtag ttcttactca tcctaataat ccaacaacta caatatttaa taaagaatct
     5761 ttagaaaaat tagctaaatt tattatagac aatgatttaa tattaatatg tgatcaagca
     5821 tttgaagatt ttacttttga aaatgaatta ataacaccag cttcattaga aggtatgttt
     5881 gaaagaacag taacaatatt ttcaacatca aaaggtatgg gattaagtgg atttagagtt
     5941 gcatatatgg tatgcagcga taaattaatg gacaaatact atggagcagc agtgacagta
     6001 ttaggtgcta ctaatacagt agctcaaatg tcaacgattg aagcatttaa agatagaagc
     6061 tttatggagg attttgaaag agtttttgat aaaagaaggc aagaagcata taagataatc
     6121 aatgaaatac ctaatgtatc tatgcagatg cctgagtccg gatttttagg ttggataaat
     6181 gtatcaaagc ttggaacatc atcagaaata caaaagtatc tagttgacga ggctaaagtt
     6241 tgtattaatg atggaattaa ttatggtcca ggaggagaag ggcatttgag aataatttta
     6301 ggaagctata aagacgatag taaggtaatt ggtgcattaa atagaataaa agatgcttta
     6361 attaaaaagc aacaataaat aaaaaataat tggagtggag tatgttatca atatttaaga
     6421 gtaaaaaaaa tgacaacaag cttaaggcat ttgcatcagg gaaagtaatt cctatagaag
     6481 atgttgatga taatgttttt tcatctaaaa tgttaggtga tggaatcgct atttatccaa
     6541 ctaatgaata tgttgtagcc ccttgtgatg cagaagtaaa tataataatg aaagatacta
     6601 aacatgcagt tggaattaaa ttatttaatg gtatggaaat cttatttcat gttggaatag
     6661 atactgtatc tatgaatgga gaaggttttg agatatttgt ttcaccaggt gacaagataa
     6721 aaagaggtga taaattaata tcttttaata gtaaattaat aaaagaagaa gggttacaag
     6781 atgtagttat aatggtagtt actaattcag aacagtataa aaatataaaa tatcatattg
     6841 gactggaggc agtaatcgat gatactatta ttgcagaaat ttaaaaacag ttatttaagt
     6901 aaatacttag ataatttaga tatagttaaa attaaatcct taaaatcaaa ttatttaatt
     6961 tttgtgtaat tttaactata aagccgatta ataatataaa gtatactaaa taatatggtt
     7021 attatgattg ttactgacaa agcctaagta gatataacaa tttgctctaa ttgagtattg
     7081 ctatatctac ttgtttttat atttaaaata aaagagtctg cattgaaaag ataattctga
     7141 tgagagtaaa tagggtattt aataatagtt taattctgac ttatcaagat gaacctattc
     7201 atatacctaa aacatcttta acaccttcta aattcataca aatagctgta taggctgcct
     7261 tattgattat ttttccgtca atttttactt tgtagtgaac agcatatata aatattatcg
     7321 aatagattgt atcaagagct ctattttgct attcattagc taaagatagt actctgtcag
     7381 ttatttttga aactaatgca tgagatatat caattccgta aatattattt aaatgtatga
     7441 tatatatcgc gagtcgacat tccttttgag tacatgccaa ttacttggtt ctctattcca
     7501 gaaatttcat tttcgtaatt ttgaataacc ctaggctgga aatcatccct agggatattt
     7561 aattttacct ctccaaaatc tgatttaaca ttcttagctc tatatccatt tcttgaattt
     7621 gatgttgctt tactttggtt atcatatctc tcgtacatta aatgatcttc aatctctgac
     7681 tctaacattt tgtgaattgt gcttgcgaat aaatctttta acatctcttg gatgtcttta
     7741 gtatttttta catcatactc ttgaactaag tgttttaata tttaattttt gttgtacata
     7801 aaaaatgtgt acctcctatt ttggtaatta gatttaatat cttgactttt aggagaatac
     7861 acattttatt ttacagaccc tcttttctag aaaagttttt atgaaaattg tgatataaat
     7921 tattaataaa aaataatttt atatttattt tattatgtaa tttagttt
//
LOCUS       DAMJVG010000124         7891 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.129, whole genome shotgun sequence.
ACCESSION   DAMJVG010000124 DAMJVG010000000
VERSION     DAMJVG010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7891)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7891)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7891
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.129"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            394..1695
                     /locus_tag="PC512_003463"
     CDS             394..1695
                     /locus_tag="PC512_003463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2443162.1"
                     /translation="MGKSKDVEIEKSILGTILLDNKLSYKLDELNENMFMNDICLEIF
                     KIMKELKKENIVIDVATVKSKIDRKSLAIKTSDVTNLITWGQNFGLDGHIKILKENLA
                     RRSINQNCQNLLHSLNLGENIDTCIYKFESNIKEILDKDTYENDDVNSIAGKVLDFLE
                     NKKDIGFKFGIKLLDTTIGGLFKGELTTIAAKSGVGKTALALQIMLNSFKQGKKTLFI
                     SREMTSEQVFMRNICRVTGVSTRNMKSKEIDENDWKLIVNAIGDLSENNLIYINDKID
                     TISAIRKRIRQVKPDLLIVDYVQLLTSQKSMDKREREVATFSRELKNMTLDFNIPVIQ
                     LSQLNDEMKDSRPYGDRPMRDSKAIYHDSNNVVYIHQLKGSDYEEAVRDIGESEEAVR
                     ASEYRGIKMVDLIVAKCRDGQTRHKHFCYFGDKLHFQELNY"
     gene            1771..2046
                     /locus_tag="PC512_003464"
     CDS             1771..2046
                     /locus_tag="PC512_003464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDF2443163.1"
                     /translation="MLELRKIIELLEEHKIEVSIPKELHKYSLLEYLELCQQSGGTYF
                     YIKTLEGALKEARNELMIKLFNGKNYMELARMFEMSVINVRHIVRKK"
     gene            3489..3719
                     /locus_tag="PC512_003465"
     CDS             3489..3719
                     /locus_tag="PC512_003465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF2443164.1"
                     /translation="MSNKKKKYANILANECVACGSCIKACPRSAISVPCGISAKINRD
                     LCVGCGICEKICPASVIEIITILKEEEGKCHE"
     gene            3712..4293
                     /locus_tag="PC512_003466"
     CDS             3712..4293
                     /locus_tag="PC512_003466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF2443165.1"
                     /translation="MNNKKHWYDYLWIFSSIYLILGFVNIIFAWIGLICFFVPLAISI
                     VKGNKAYCNKYCGRGQLFNLLGNKLKLSRNRDIPKFIRSKWFRYGFLTFFMVMFANML
                     FSTYLVFEGSRNFKEVVTLLWTIKMPWQWAYHGTLVSPWVVQFAFGFYSVMLTSTVLG
                     LITMILFKPRSWCVYCPMGTMTQMICKAKSKSI"
     gene            complement(4868..5545)
                     /locus_tag="PC512_003467"
     CDS             complement(4868..5545)
                     /locus_tag="PC512_003467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HDF2443166.1"
                     /translation="MISQNEIDILTHSLPFWDKLTDLQKELLISSANTSHYKKGNPVH
                     CGDSDCIGILIIKSGTVRTYILSDEGREVTLFRLDDGDVCILSASCILKTITFDVYVD
                     AETDCDIIQISSSVFAKLSTENIHAELFSYKLATERFSDVMWAMQQILFMSFDKRLAS
                     FLIDEIAKNGSSTINMTHEQIAKYMGSAREVVSRMLKYFAREGIVSLSRGGIKVLDKD
                     KLRSLTL"
     gene            complement(5734..7098)
                     /locus_tag="PC512_003468"
     CDS             complement(5734..7098)
                     /locus_tag="PC512_003468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2443167.1"
                     /translation="MKESNKRIELLGSAPISKALLSMGLPTMIGMMITALYNLVDAYF
                     VGGLGTSQMGAISVAFPLGQLVVGLGLLFGNGAASYIARLLGHGDNEKAGKVVSTSIY
                     SSIIVGTLVIIVIMIFLNPILKLLGATKSIMPYAISYASIYVVSSIFNIFNVTMTNIV
                     TSEGAAKTTMCAMLLGALLNMILDPIFIYTFGLGVRGASIATAISQIASTLVYVGYIL
                     SKKSIFSFRINECCFSKEIFSEILKIGIPTLIFQLLTSLAITLTNMEATKYGDSVIAG
                     MGAVTRITSLGSLVVFGFIKGFQPIAGYNFGSKNYDRLHIAIKTSILWTTIFCVVLGL
                     ILILFPKSIISQFTSGDILLIENGSKALRANGFSFMLFGFYTVYSTLFLALGKAKEGG
                     FLGMCRQGVCFIPIILIIPVFYGLNGILYAQPIADLMAAIIAGFMSIRLHKELNLLKI
                     NGMH"
     gene            7226..7747
                     /locus_tag="PC512_003469"
     CDS             7226..7747
                     /locus_tag="PC512_003469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDF2443168.1"
                     /translation="MATIDLIVLGIVKQQPKSAYDIQKAVEYRNISRWVKISTPSIYK
                     KVIQLEQKGYIESKTVKNGKMPEKAVYSLTELGETHFLDLMFDTSSKPINILLDFNAV
                     IVNLNSLTPEKQKLCLNNIEENVQELKKTIEENISIKTEVPDTAKAVLEQQLVLAQAL
                     ETWINSLKDNMGN"
BASE COUNT         3084 a          881 c         1362 g         2564 t
ORIGIN      
        1 tcaagtagtg aattatattg aacgatatat taataattgg aagtaagtta tatcaaataa
       61 gatattacta tcaagtagtg aattatattg aacgatatat taataattgg cagtaagtta
      121 tatcaaataa gatattacta tcaagtagtg aattatattg aacaatatat taataattgg
      181 tagtaaagta tatcaaataa gatattgcta ttatgtagta aattatataa aacaatgtat
      241 cagaataaat agtatattaa taatttgtag tatatcatga cgaataatac agtcataaca
      301 aatagtgagt cataacaaat aatgtattta taattgataa tgtatttaaa aatcaaaata
      361 taaaaactta taaggaaaga gagattaatt tatatgggta aatcaaaaga tgttgaaata
      421 gagaagtcta ttttaggcac aattctttta gacaataaat taagctataa gctagatgaa
      481 ttaaatgaaa acatgtttat gaatgatata tgtcttgaga tatttaaaat tatgaaagaa
      541 cttaaaaaag aaaacatagt gattgatgtg gccactgtga aatcaaagat agatagaaaa
      601 tctctagcaa taaaaacgag tgatgtgact aatctaatta cttggggtca gaattttggt
      661 cttgatggtc atattaaaat tttaaaagaa aatttagcta gaagaagcat aaatcaaaat
      721 tgccaaaacc ttttacacag cctaaacctt ggagaaaata tcgatacttg tatttacaaa
      781 tttgaaagta atataaagga gattttggac aaggatactt atgaaaatga tgatgtaaat
      841 agtatagcag ggaaggtgct tgatttttta gaaaacaaaa aagatattgg atttaaattt
      901 ggtataaaat tacttgatac cactatagga ggtcttttta aaggagagct aaccacaata
      961 gcagctaaat cgggggttgg gaagactgct ttggcacttc aaataatgtt aaattcattt
     1021 aagcaaggta aaaaaacttt atttataagt agagaaatga ccagtgagca agtatttatg
     1081 agaaatatat gcagagtaac tggtgtaagt acaaggaata tgaaatctaa agaaatagat
     1141 gaaaatgatt ggaaacttat tgtaaatgct ataggtgatt taagcgaaaa taacttaatt
     1201 tatattaatg ataagataga tacaattagt gcaattagaa agaggataag gcaggtaaag
     1261 ccagatttat taatagtgga ttatgtgcaa ctccttacat ctcagaaaag catggataag
     1321 agagaaaggg aggtagctac tttttcgaga gaacttaaaa atatgacttt agattttaat
     1381 atacctgtaa tccaattaag tcagttaaat gatgaaatga aagattcaag accttatgga
     1441 gatagaccta tgagggatag caaagccatc taccacgata gcaacaatgt ggtttatata
     1501 catcaattaa aggggagtga ttatgaagaa gcagtgagag atattggaga aagtgaggag
     1561 gcagttagag catcagaata caggggaatt aagatggttg atttaatagt tgcgaagtgt
     1621 agagatggac agactaggca taagcatttt tgttactttg gggataagtt acattttcaa
     1681 gaactaaatt attaggtcaa taaagtagta ataacaagct tattaaaagt cgggaaatag
     1741 caaatagatt ataaaatatg aggtgaaaat atgttggaat taagaaaaat tatagaatta
     1801 cttgaagaac acaagataga agtaagtatt ccaaaggagt tacataagta tagtttattg
     1861 gaataccttg aattgtgtca acaaagtggg ggaacatatt tttatattaa aacactggaa
     1921 ggggctttaa aagaggctag aaatgagctt atgattaaat tgtttaatgg gaaaaattat
     1981 atggaattag cgaggatgtt tgaaatgagt gttattaatg tcaggcatat tgttagaaaa
     2041 aaatagatat ttttggagaa tacaagtgtg atatacttct gaaatagaag ttattatagt
     2101 tgaaataaaa ttgtggttaa taaattaaag ttgtgtataa gtttaagatt atagaggagt
     2161 ataagtgtga ttaacagcat gattttgtga ataaaattga ggatatatat gagttaaatg
     2221 tgtgattaat aaggtaaggt tgtgtataag attatgagta tttaaaagga ggggctataa
     2281 ttaatagtgt agagttgtgt gtttgcttaa gattatataa taatttaata gattaaacta
     2341 tactaataag gtaaaatcgt gtgtttagtt aaagcttatt ataaaatctt gatatgtgat
     2401 taatgatgca atatgtgaat aaagttaaga ttataataga tttaacctgt ggctaataga
     2461 ataaaattgt gaataaagtt aagattataa taggtttaac ctgtgattaa tagagtaaga
     2521 gtgtaaatag agataaactt caatatgagc ttaacctatg attaatagag taagagtgta
     2581 aatagagata aacttcaata tgagcttaac ctatgattaa tagagtaaga gtgtaaatag
     2641 agataaactt caatatgggt ttaacttgtg attaatagag tagggtgtaa ctaaagataa
     2701 acttcaatat gagtttaact tgtgattaat agagtaaggt gcaactaaag ataaacttca
     2761 atatgagctt aacctatgat taatagagta agaatgtaaa tagagataaa cttcaatatg
     2821 ggcttaactt gtggttaata gagtaagagt gtaactaaag ataaacttca atatgggttt
     2881 aacttgtggt taatagagta agaatgtaaa tagagataaa cttcaatatg agcttaactt
     2941 gtgattaata gagtaagagt gtaaatagag ataaacttca atatgggatt aacttgtgat
     3001 taatagagta agagtgtaac taaagataaa cttcaatatg agcttaacct atgattaata
     3061 gagtaagaat gtaaatagag ataaacttca atatgggttt aacctgtggt taatagagta
     3121 gggtgtaact aaagataaac ttcaatatga gtttaacttg tggctaatag aataagattg
     3181 tgaataaagt tatagtttta gatgggtatt aacctgttac taatagaata tgattaggtg
     3241 taaaattata gagctgtata agaaaatatt atagatatat taaatattag ataataaata
     3301 tttatataga tacacaaaag aaaaggcgat atgaagctaa acttaatgac ttcatatcgt
     3361 tttttatttg aaactccttt gtatttagag tgtgattttt aatattgagg ttttatgtga
     3421 ttaagtcaca gataaaaagt aagtatcttg atataattct tatagattaa taatataggg
     3481 aggttattat gtctaataaa aaaaagaagt atgcaaatat tttagcaaat gagtgcgttg
     3541 cttgtggtag ctgtataaaa gcatgtccaa gaagtgctat ctcagttcca tgtggcatta
     3601 gtgcaaaaat taatagagat ttatgtgttg gatgtgggat ttgtgaaaag atatgtccag
     3661 catctgtaat tgagattata acaatattaa aagaggaaga aggtaagtgt catgaataat
     3721 aaaaaacatt ggtatgacta tttatggatt ttttcttcaa tatatttgat attgggattt
     3781 gtaaatatta ttttcgcttg gattgggcta atttgtttct ttgttccact agctatttct
     3841 attgttaagg gaaataaagc ttactgtaat aagtattgtg gaagagggca actgtttaat
     3901 ttgcttggaa ataaattgaa gctgtcaaga aatagagata ttcctaaatt tattagaagt
     3961 aagtggttta gatatgggtt tttgacattt tttatggtaa tgtttgccaa tatgcttttt
     4021 tcaacttatt tagtgtttga aggaagtaga aattttaaag aagtagtgac tttgttgtgg
     4081 actataaaaa tgccttggca atgggcgtat catggaactt tagtttcacc ttgggtggta
     4141 cagtttgcat ttggttttta tagtgttatg cttacatcaa ctgttcttgg tttgattact
     4201 atgatattgt ttaaacctcg ttcatggtgt gtttattgcc ctatgggtac tatgactcag
     4261 atgatatgta aggcaaagag taagtctata tagaaaggct ttatgtgata tttacagttt
     4321 tgttagagat gagtagtagg tttgaatata tatgacaaat atatgagtat aggggcatag
     4381 atttagtttg tgtaaggtaa actgatttat gcttcttttt tatgtcttag attattggct
     4441 aagtggaaac aatgaattta gatattaaga attattcagt tatttgaaga aaatagaata
     4501 ataattaaca ttatatgaat ggatattcat tacatataag ccagttaata gcaagattta
     4561 tttaatatga aataggtcaa gtatttaaac taaataaggt catgacaatt aatataagta
     4621 tagatataaa aagattagaa gttataactt ataaaaggta ttctatataa atagtatgtg
     4681 gaaaatagtc aaattaactt attagaaaca aaaaatatac ataaaaaaat aaatgtaaat
     4741 atcaaataag atactatata aaaatagata taagtatctt ttttattatt gaaattatga
     4801 aaatatattt gatttcacac aaaaaagagt gcctcatgaa ctaaaaagtt cattttgaga
     4861 cacactttta cagtgtcaaa gaacgaagtt tatccttatc caatactttt ataccaccac
     4921 gagataaaga cacaatacct tctctagcaa aatatttcaa cattctcgat acaacttctc
     4981 tggcactacc catatactta gcaatttgct catgagtcat atttatagtg ctactgccat
     5041 ttttagctat ctcatcaatt aaaaaagatg ccaaacgctt atcaaaactc ataaaaagaa
     5101 tttgttgcat agcccacata acatcagaaa aacgttcggt agctaattta tatgaaaata
     5161 actctgcatg aatattttct gtagataatt ttgcaaaaac agaggaacta atctgtataa
     5221 tatcgcagtc cgtttcagca tctacataga catcaaaagt tattgttttt agaatacagg
     5281 aagctgataa aatacataca tctccatcat caagtcggaa cagtgtaacc tctcgacctt
     5341 catctgaaag tatgtatgta cgtactgttc cagactttat aatcaaaata ccaatacagt
     5401 cactatcacc acaatgtact ggattccctt ttttgtaatg cgaggtattt gctgaagaaa
     5461 ttaataattc tttttgtaag tcagtaagtt tatcccaaaa aggcaagcta tgtgtaagta
     5521 tatcgatttc attttgtgaa atcatacaat atctcctttc ttaaattgtt ataatcccat
     5581 gatacaagtg aatagataaa ttgacaagta gtttgttaat aggattattt agtcagatag
     5641 taatagtatg atttatgtag aaaaaatatg ataatatata ttcttgctat taatgagaag
     5701 gtaatatgtt ttgatgatag taggtttgta taactaatgc ataccgttta tttttaaaag
     5761 attaagttcc ttatgtaacc ttatagacat aaaaccagca attatagcag ccatcaaatc
     5821 agctattggt tgtgcatata agataccatt taacccatag aatacaggaa taatcaaaat
     5881 tatagggata aaacagacac cttgtctaca catacctaaa aatccacctt cctttgcttt
     5941 tcctagtgcg aggaataatg tagaatacac tgtatagaat ccaaatagca taaatgaaaa
     6001 cccatttgcc ctaagagctt tactaccatt ttctattaat agaatgtcac cacttgtaaa
     6061 ttgtgaaatt atagattttg ggaagagtat caatataaga ccaagcacta cacaaaatat
     6121 tgtagtccat aatatggaag tttttattgc tatatgtaat ctatcgtagt tctttgaacc
     6181 aaaattataa ccagcaattg gttggaaacc ttttataaaa ccaaatacaa caagactacc
     6241 taaagacgtt attcgtgtta cagcacccat tccagctatc acagaatcac catactttgt
     6301 agcctccata ttagttaatg taatggcaag actagtcaat aattgaaata ttaaggtagg
     6361 tatgccaatt tttaggattt ctgaaaaaat ttcttttgaa aaacagcatt cgttaattct
     6421 aaaactaaat atacttttct tgcttaaaat atatcctaca taaacaagtg ttgaagcaat
     6481 ctgtgagata gctgttgcaa tagaagcacc ccttaccccc agaccaaaag tataaatgaa
     6541 tattgggtct aaaatcatat taagcaaagc acctaataac atagcacaca tagttgtttt
     6601 agcagctcct tcacttgtga caatattagt catagtgaca ttgaatatat taaaaataga
     6661 tgacacgaca taaatgctag cataagatat tgcataaggc ataatacttt ttgtagctcc
     6721 taacaatttt aaaattggat tgagaaaaat cataatcaca ataataacta atgtacccac
     6781 tataatacta ctgtaaatag atgtacttac cacttttcct gctttttcat tatcaccatg
     6841 gcctaaaagt ctggcaatat atgaagcagc tccatttcca aacaataatc ctaatcccac
     6901 aacaagctga cctaatggaa atgcaacgga tatagctccc atttgacttg ttccaagtcc
     6961 acccacaaag tatgcatcaa ccaaattgta taatgcagtt atcatcatac ctatcatggt
     7021 aggtaatccc atagataaca atgcttttga gattggggca gaccctaata attcaattct
     7081 tttgttactt tctttcatac ttaacactcc tcttctattg acattaagtc taaattataa
     7141 tactataaat tatagtaagt atggaaaata gtactataat ttatagtatt tgtcaatagt
     7201 aagaaaacta aaggagatga tttttatggc tacaatagat ttaattgtat tgggaatagt
     7261 aaagcaacaa cccaagagtg cttatgatat tcaaaaggca gtggaataca ggaatatatc
     7321 acgttgggtt aaaataagta caccatcaat ttataaaaaa gtaattcaat tagaacaaaa
     7381 gggatatatt gaaagtaaaa ctgtgaagaa tggaaaaatg ccagaaaaag cagtttattc
     7441 attaactgaa ttaggtgaga cacatttttt agatttaatg tttgatacat ctagcaaacc
     7501 aataaatatt cttttagatt ttaatgctgt tatagtaaat ttaaatagcc ttacaccaga
     7561 aaaacagaaa ttatgtctca ataatattga agagaatgtt caagagttaa agaaaactat
     7621 tgaggaaaat ataagtataa agacagaagt accagacaca gcaaaagcag tgttggagca
     7681 acagttggtg ctagcacaag cattggaaac ctggataaat tctttaaaag ataatatggg
     7741 aaattagaat tagagaagct aacttaataa tcattaaaca aaaaccagca tatttaataa
     7801 tgagatatta gaaaaaataa aacaaatgat ataaactgaa aagtatattt aaaataaagc
     7861 tcacttaatt gagggagaat gttaaacttt t
//
LOCUS       DAMJVG010000125         7421 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.130, whole genome shotgun sequence.
ACCESSION   DAMJVG010000125 DAMJVG010000000
VERSION     DAMJVG010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7421)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7421)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7421
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.130"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            269..1081
                     /locus_tag="PC512_003470"
     CDS             269..1081
                     /locus_tag="PC512_003470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDF2443169.1"
                     /translation="MYLERPELYKQSEINFWDDEYISKQLLKAHLDTNFEGASRNFNF
                     IEDSVNWIVTVANPANYPKLLDLGCGPGLYAEKFAQKGYKVTGIDFSKRSINYAQNRN
                     KETNLNINYLFQSYLNMNYNEEFDLATLIYCDYGALSTENRRLLMEKIYDSLKPGGKL
                     ILDVFTINKYNNFEEIKYWEINEDGGFWSNEKYMCLQDNCKYNDYNTLEQTLVITEKD
                     ENVFYVWNHYFSKESFLLEVENIGFKSVEFFSNVKGEAYSDDSMTMGLVLQK"
     gene            2129..2890
                     /locus_tag="PC512_003471"
     CDS             2129..2890
                     /locus_tag="PC512_003471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896901.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HDF2443170.1"
                     /translation="MIGIYFSGTGNSRYCVEKFLQEYDITANSYSIEDNELLQHINNH
                     ENIIFSYPVQYSNVPKILKDFIINHSTLWNGKRVFIIATMALFSGDGSGVLSRILKKY
                     GAITVGGLHVKMPDSIGDEKVLKHSLEYNRKLVIKAEKKVTKAAKKLKHGSPPKEGLG
                     FLSHIVGLFGQRLYFINKTNMYTDKLKINTEECIVCGKCVNLCPMKNLVIKNCMIVAN
                     GQCTMCYRCVNNCAKKAITLLGKKVVEQSNIKKYM"
     gene            2955..3737
                     /locus_tag="PC512_003472"
     CDS             2955..3737
                     /locus_tag="PC512_003472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HDF2443171.1"
                     /translation="MEYYIVDSFATKLFKGNPAGVCVLDRRIPLELMQKIAEENNLPE
                     TAFVVKGKGNYELRWFTPKAEIDLCGHATLAAAYVISNFIDVNVKRIDFFTQSGKLEV
                     TRNGNLYEMIFPEIMPIEIELSPQQANLIGCVPSAVYSSRDLILLLNSEQEVINYKPN
                     YAQLRKLTDWLGIIITAQGSNTDFVSRYFCPELDSEDPVTGSSHCNLIPYWSEKLGKH
                     KMVAAQLSNRGGIIQCEVLKDNTVKISGEAVLFMQGTIKIDI"
     gene            4004..4423
                     /locus_tag="PC512_003473"
     CDS             4004..4423
                     /locus_tag="PC512_003473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjdF family protein"
                     /protein_id="HDF2443172.1"
                     /translation="MDKISGKLTVLFEEPFWVGIFERQDGKKYEACRVVFGAEPKEVE
                     VYEFILERFFSLDFGSIKLEKNVTKDNIGYKRMQRKVKKEQEKETIGTKAQNALKLQY
                     EERKQDRKNLAKNRKEEEKERLFNLKQEKRKAKHKGH"
     gene            complement(4526..4792)
                     /locus_tag="PC512_003474"
     CDS             complement(4526..4792)
                     /locus_tag="PC512_003474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HDF2443173.1"
                     /translation="MKNFILIYFIVINSIAFFSMYIDKKRAIRNEWRIKEATLMSIAV
                     IGGSIGSIIGMYSFRHKTKHIKFTFGIPFILFLQFLLVYFYILK"
     gene            5019..5720
                     /locus_tag="PC512_003475"
     CDS             5019..5720
                     /locus_tag="PC512_003475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443174.1"
                     /translation="MKFIVEKEVFDKLENVCFGVVVAKGIDNTKEIERISNLLDISID
                     RVEDYFKDKKVKESEEIIPYREAFRSLGMNPNKFMSSIEAMTTRVAKNKKLPHINPIV
                     DLGNSISLKYLLPMGAHDMDFRNDDVYVRFSKKGDKFVPFGETDVELMEEGELIYSVG
                     DMVKTRRWIWRQGEEGKITNSSKNIFFPIDGFTDANLDKVMSAREELAKLLKEIFNCE
                     IKVGFVDKDNPEMEI"
     gene            5802..6410
                     /locus_tag="PC512_003476"
     CDS             5802..6410
                     /locus_tag="PC512_003476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HDF2443175.1"
                     /translation="MKKTIIKNVNPMIENKFIGLFEIEYKNKLDEDKVWMVASRKSSE
                     QLKNIYLKNEEDSVDAVVIVGLHKSSKKLILIRQFRVPINGYIYELPAGLVDEGESID
                     ISVERELREETGLTLLEIKKNKSIDKVYLSPGMSDESVAFVYCICDGDITDEFLEPDE
                     EIEALLISQEDAKEILQSNHKIDTKAFLILQMFVSLGAKLFE"
     gene            6734..7198
                     /locus_tag="PC512_003477"
     CDS             6734..7198
                     /locus_tag="PC512_003477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4624 domain-containing lipoprotein"
                     /protein_id="HDF2443176.1"
                     /translation="MKKLVIILISIISMVSLTACKKSNESKYNNLNNKESGQTTIEMD
                     LDKNYDTSDPFVNARLFCVSNDIDVLDTEISFKMDGDSGIVEIKDNKTDETLWSNTWH
                     GSVDNDTFTISLSNIQKEKEYAICFTGIKINHAVVKVTFESNLVKEKEKPSK"
BASE COUNT         3028 a          673 c         1254 g         2466 t
ORIGIN      
        1 aaaaatatga aaggatgatg ttgttcggtg atatttgata tcataaaatc gttgatataa
       61 gtattgctgg aaaagagtga ataaaatcaa atttaataag caaacaaagt aaagctatag
      121 ttttattgtt gtgcttaaaa atatttggtt ctattttact cttatttaaa ctcatctttt
      181 tgaagttaaa ccacagagta aactctgtgg tttttttatt ttaaaaataa attttaagga
      241 gtggtatgtt ttgttaaaca aattatgtat gtatttagaa agaccagagc tttataaaca
      301 aagtgaaatt aatttttggg atgatgagta tatttcaaag caattattaa aagcacactt
      361 agacactaat tttgaaggag caagtagaaa ttttaacttt atcgaggatt ctgtaaattg
      421 gatagttaca gttgcaaatc cagctaatta tcctaaatta cttgatttag gttgtggtcc
      481 aggtttatat gcagagaaat ttgcacaaaa aggttataag gtaactggaa ttgatttctc
      541 aaaacgttct attaactatg cacaaaatag aaataaggag actaatttaa acataaatta
      601 cttgttccaa agttatttaa atatgaacta taatgaggaa tttgatttgg ctactttaat
      661 ttattgtgat tatggagctt tgtcaactga aaatagaagg ttattaatgg aaaaaattta
      721 tgatagttta aaacctggag gaaaattaat attagatgta tttacaataa ataaatacaa
      781 taattttgag gaaattaaat attgggaaat aaatgaagat ggaggatttt ggagtaatga
      841 aaaatatatg tgtctacaag ataattgtaa atacaatgat tataatacat tagaacaaac
      901 tcttgtaata accgaaaaag atgaaaatgt attttatgtt tggaatcact atttttcaaa
      961 agaaagtttc ttattagaag ttgaaaatat tggatttaag tctgttgagt tttttagtaa
     1021 tgttaagggt gaagcatatt ctgacgatag tatgactatg ggattagttt tacaaaaata
     1081 ataatttttt taaaatgaat aaataaaaac ttgaaacctt taacaataaa ataacataat
     1141 aaaagcttac atattgaaaa atggaaactt ttatgttatt tttagtacat tacaaatttg
     1201 cttatataaa aatcaatact tgaattatta tttttatgtg aaatttatct atagtatatt
     1261 tttataaaca agtaatgtta ttaaaattaa gtatgtagtt aaaagtgtat agcaaaaagg
     1321 ctgttatatt aatgttagag gttcagggaa aatatataaa gcaaagtatt tacagataat
     1381 gtagattgca cagctataag ttagataata gaattatgta atcaagaatt tacaacaaag
     1441 tataagataa ggataatgct aaattgccat acaggtgcta gatgtgtaaa tggatttaat
     1501 taatactatt gataaagtgc aacaagcaca taaaccaatt gatgagatta ttaaaactat
     1561 aagagatata gttgacataa ttaaaatatt ggaacttgtt tataatttta aatcaaatca
     1621 ataatgatta agattaaaat aatattaagg catcaatgtt ataagagtac aatataagga
     1681 gtactatata gtactcctta cttatacata ttaggcaata ggaaattttt tcatagttaa
     1741 attttcaagt attttttagg aaactttata attgagaatt aagggtatag tatgtgatga
     1801 acttactgaa tttataatta ggttatataa tggaataatc atcaatagtt ttactttagg
     1861 gaaaatatat gcttaaggaa gtatagctta ctaatattat taaaatgtat atttaaaatg
     1921 ataaaaaaag aattagacaa gtatttagta aattgactat gcaaaattct atcaagcagg
     1981 aaccctatga ctttagtcat gggaggttca gtaggtaact tgttgaatta agtttatatt
     2041 atttaaataa actacttaat ttagataata taaaaagtca gaattttaag aatagagcta
     2101 tataatctta gctattagga gaattactat gataggaata tattttagtg gaacaggaaa
     2161 ttcaagatac tgtgtagaaa aatttttaca agaatatgat ataacagcaa attcttattc
     2221 tattgaagat aatgaacttt tacagcacat caataatcat gagaatatta tttttagtta
     2281 tccggtgcaa tatagtaatg tgccaaaaat attgaaagat tttataataa atcattcaac
     2341 tttgtggaat ggtaaacgtg tttttattat tgcaactatg gctctattta gtggagatgg
     2401 ctctggtgtg ttatctagaa tattaaaaaa atacggtgct ataactgttg gtggattaca
     2461 tgtgaagatg ccagatagta taggagatga aaaggtatta aaacattctt tagagtataa
     2521 tagaaagctt gtaataaaag cagaaaagaa agtaactaaa gctgctaaaa aactgaaaca
     2581 tgggtcacca ccaaaagaag ggttaggttt tttgagtcat attgtagggt tatttggaca
     2641 acgattgtat tttatcaaca aaacaaatat gtatacagat aaactaaaaa ttaatactga
     2701 ggaatgtatt gtatgtggta aatgtgttaa tttatgtcca atgaagaatc tagtaattaa
     2761 aaattgtatg attgttgcaa atgggcaatg tacaatgtgt tatcgttgtg taaataattg
     2821 tgctaaaaaa gcaattacat tgttaggtaa aaaagttgtt gaacagagta atattaaaaa
     2881 atatatgtaa gaaatttaaa gttttattga atgtaaattg atgtatattt tatgttagaa
     2941 agagaggtta aataatggaa tactacatag ttgattcatt tgcaactaaa ctatttaaag
     3001 gaaatcctgc tggagtttgt gttcttgaca gaagaatacc tttagagtta atgcagaaaa
     3061 tagcagaaga aaacaattta ccagaaacag catttgtagt taaaggtaaa ggaaattatg
     3121 aattacgatg gtttactcct aaagcagaaa ttgatttatg tggtcatgca actttagcag
     3181 cagcttatgt aatatcaaat tttattgatg ttaatgtaaa aaggatagat ttctttactc
     3241 aaagtggaaa gcttgaagtt acacgaaatg gaaatctata tgaaatgata tttccagaaa
     3301 taatgcctat tgaaatagag ttatcaccac aacaagctaa tttgataggc tgtgtaccaa
     3361 gtgctgttta ttcttcaaga gatttaatct tattgctaaa cagtgaacaa gaagttataa
     3421 attataaacc taattacgca caattgcgta aattgacaga ctggttaggt ataataatca
     3481 cagcacaagg aagtaataca gattttgtat caagatattt ttgtccagaa ttagattcag
     3541 aagaccctgt tactggttca tcacattgta atcttattcc atactggtct gaaaagttgg
     3601 gaaaacacaa aatggtagct gctcaacttt ctaatcgtgg tggtataatt cagtgtgaag
     3661 tgttgaagga taatactgtg aaaatttctg gtgaagcagt cttgtttatg cagggaacaa
     3721 taaagattga tatttaaata agtataataa ctaatttatt atgaaaaata attaattttc
     3781 ttagtgttaa caataataaa gtagagttaa aaaacttgat ttcacttaaa tcaatatgat
     3841 agatgttgat actaagattg acaagcatga ttaaaaaaga taatatttaa tctataaaga
     3901 taaaaacaca gtctggttgg tagtccagac gcagcaatag ctgtcagtaa cctgcctcct
     3961 tggttgtccg ttctttagaa agtaatttaa ggaggaacta gcaatggaca aaattagtgg
     4021 aaaattaaca gtcttatttg aagaaccatt ttgggtaggt atatttgaaa gacaagatgg
     4081 taaaaaatat gaagcatgta gggtagtttt tggagcagaa cctaaagaag tagaagtgta
     4141 tgaatttata cttgaaagat ttttctcatt agattttggt agcattaaat tagaaaaaaa
     4201 tgtgaccaaa gacaacattg gatacaaaag aatgcagaga aaagtaaaaa aggaacaaga
     4261 aaaagaaact atagggacta aggctcaaaa tgctcttaag cttcaatatg aagaaagaaa
     4321 acaggataga aaaaacctag ctaaaaatag aaaagaagaa gaaaaagaaa gactatttaa
     4381 tttgaaacaa gaaaagagaa aagctaaaca taagggtcat taattttaat taaatatctt
     4441 tttaataatt gctagaaaaa ggtgtataaa atttttaatt ttatacacct taatttattg
     4501 aaaagaataa ggttttatat ttcaattact ttaaaatata aaaatatact aataaaaatt
     4561 gtaaaaatag tataaatggt ataccaaatg taaatttaat gtgtttagtt ttatgtctaa
     4621 aagaatacat tccaattata gaacctatac tacctccaat tactgctata gacataagag
     4681 tagcttcttt tattctccat tcgtttctaa ttgctctttt cttatctatg tacattgaaa
     4741 agaaagcaat agaattaatc actataaaat atattagaat aaaatttttc acagtcttgc
     4801 ctccataaaa atatattata cattataaaa caagatattt gttttggaaa gttaaatttg
     4861 taattagtac atataaaata tttgataaga acaaatataa tattaattgg aaaatttaaa
     4921 aaaattaaac aattagcaaa tagggggtat atttataaga cacaaagtga taaaatctat
     4981 ttagaaaata atgtaaaata acaggaggat aaagcaaaat gaaatttata gtagaaaaag
     5041 aagtttttga taaattagaa aatgtatgct ttggtgtagt agttgcaaaa ggaatagata
     5101 atactaaaga aatagaaaga ataagcaacc ttttagatat aagtatagat agagtagaag
     5161 attacttcaa agataaaaaa gtaaaggaat cagaagaaat tataccatat agagaggcat
     5221 ttagaagtct aggcatgaac ccaaataaat ttatgagttc gatagaagca atgacaacaa
     5281 gggttgctaa gaataagaaa cttcctcata taaatcctat tgtagattta ggaaactcta
     5341 tttctttaaa atatttactt ccaatgggtg ctcatgatat ggattttaga aatgatgatg
     5401 tatatgttag attttctaaa aaaggggata aatttgtacc atttggagaa actgatgttg
     5461 aattaatgga agaaggagaa ttaatttatt cagttggaga catggtaaaa actagaagat
     5521 ggatatggag acaaggagaa gaaggaaaaa ttactaatag ctcaaaaaat atattttttc
     5581 ctatagatgg ttttactgat gctaatttag ataaggtaat gagtgcaaga gaagaattag
     5641 caaaattgtt aaaggaaata tttaattgtg aaattaaagt aggttttgta gataaagata
     5701 atcctgaaat ggaaatataa taagttgttg aatacttgtt aagatattat atttacttaa
     5761 tgatgttaaa aaggtattaa aaaagaaagg tcgtagtaaa tttgaaaaaa actataataa
     5821 agaatgtaaa tccaatgatt gaaaataagt ttataggact ttttgaaata gagtataaaa
     5881 acaaattaga tgaagataag gtttggatgg tagcatcaag aaaaagtagt gagcaattaa
     5941 aaaatattta tttgaagaat gaagaagata gtgtagatgc agttgtaata gttgggcttc
     6001 ataaaagtag taaaaaatta attttaataa gacaatttag agtacctatt aatggatata
     6061 tatacgagtt accagcaggt cttgttgatg aaggagagtc tatagatatt tccgttgaaa
     6121 gagaacttag agaagaaaca ggacttactc ttttagaaat taaaaaaaat aaaagtattg
     6181 ataaagttta tttatctcct ggaatgagtg atgaatctgt tgcctttgtt tattgtatat
     6241 gtgatggtga tataacagat gaatttttag aaccagatga agagattgaa gcgcttttaa
     6301 tttcgcaaga agatgcaaaa gagattttac aaagtaatca taagatagac acaaaagcat
     6361 ttttgatttt acaaatgttt gtgagtttag gagctaaatt atttgaatag atatatagaa
     6421 aagaggttat atagaagagt aaaataataa agtttatttt acttgtgtaa attataatct
     6481 ctttttttat acaataaagt ataattttgt gtatttttaa ataagtgatt tgactcttaa
     6541 attttcataa tatgttataa accaatttaa gatactacaa taattaaaat tccaaaatta
     6601 tttaacatat ttgcaattaa aatgagaaaa tgtaaaggct gaatgattga aaaatttgat
     6661 gtaaaatagt agcttagttt aatactatag tttgtagggt taaaaattag aaattgtaag
     6721 ggagataaat tctatgaaaa aattagttat tattttaatt agtatcatta gtatggttag
     6781 cttgacagct tgtaaaaaaa gcaatgaaag taaatataat aatttaaaca acaaagaatc
     6841 cggacaaaca accattgaaa tggacttaga taaaaattat gatacttcag acccatttgt
     6901 taatgcacgt ttgttttgtg tgtctaatga tatagatgtt ttagacacag agatttcttt
     6961 taaaatggat ggagatagtg gtattgtgga aataaaggac aataaaacag atgaaacttt
     7021 atggagtaat acatggcatg gaagcgttga taatgataca ttcacaattt ctctttctaa
     7081 tatacaaaaa gagaaagagt atgctatatg ctttactgga attaaaataa atcatgcagt
     7141 tgtaaaggtt acttttgaaa gcaatttagt taaggagaaa gaaaaaccct caaaataaat
     7201 tccagctttt ctataacttg atattcagta cataaaagca gttgatattt atgattgact
     7261 gctttttctt atcaaaaagg ataggttgtg catttttact tgaaatagtt tatgcacatc
     7321 aaaagttggt gagcatgata ttggaaatgg taagcatgaa atcttgataa tacaaggaaa
     7381 taaatttaag ttttcaatta agtatatttc cataatttag t
//
LOCUS       DAMJVG010000126         7381 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.131, whole genome shotgun sequence.
ACCESSION   DAMJVG010000126 DAMJVG010000000
VERSION     DAMJVG010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7381
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.131"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            203..3382
                     /locus_tag="PC512_003478"
     CDS             203..3382
                     /locus_tag="PC512_003478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDF2443177.1"
                     /translation="MKIDMIYKLIRRNTEPSRWSRGVKYYTNQLVDYIDIDIDDLQNN
                     LLTFRGGVNSEDNYSFYFNSITIDIKHFKIIENDCSCADCQSKGKSIFICKHIVAIVI
                     KSLKQIKNKKDVPPILIDILGADKDKLSNTNSKTSLDLSKQLLSLLDNTKRERVNLDV
                     LINVDSNKAIAEFKIGIDKMYILKNITEFAYSKLNGYELDFGKKFTYNPNTHYFADED
                     EKLVDIIEEYGTNLSYNFSSSHSKKFMEINASSLKQFLNAIKYKDFTLIFSKEEYHPK
                     ILNDTLPVRFDFKNIEDKIVLYSKDSLPVPLTKKNDVLLYDGNIYLLSHKKAHDYSKI
                     YQILSKTKELKFDKEDSKDVLGLLVPRLKSISQEVHLDDNIKNNITKDFKSEFYFDMI
                     DGNICCDVKYIYDDEDKKFVLPNIQKEATIENKLTSSQFTKENNHYVFKGTDHDLFTF
                     LDLQLESLKEFGDIYYSEKFKLKKIYNASSIQASINQTNQNYLEFNFNISDINPREYK
                     DILKAFQEKRTFYKLKDGNFIDLSERETKDFFELVENLDIMDKSKNNKIHKNKALYIN
                     DVIRSKNLKFIDGKKELDSICEKFRNFDSINLEIPANLNANLRDYQINGLNWFKVLDY
                     YKFGGILADEMGLGKTIQTIAFLLSLSNKKSLIVTPTSLIYNWKNEFEKFAPDIKVLL
                     IHGNKRDREKCFMELENFDVILTTYGTLRNDLEKYSEIKFDYCILDEAQNIKNPVALV
                     TESVKSINAENKFALTGTPMENNLLELWSIFDFIMPGYLYSKAKFQELFINKEDNVKN
                     LKKLIKPFILRRSKKQVMKELPDKIEKNFFVELNKEQKKIYSVYSKDIQDKMKDKNLK
                     KDKIVIFSYLTKLRQLCLDPSIVVKDYNKKSSKIETCLEILRDSINENHKILLFSQFT
                     SVLKNISKELDKYKIKYHYIDGKTNAKERLELVDEFNNSMDKKVFLISLKAGGTGLNL
                     TSADMVIHFDPWWNPSVENQASDRAHRFGQKNSVQVIKLIAKGTIEEKIIKLQESKKE
                     LINQFINGELSNEGVLKSLSDEEIINLFN"
     gene            complement(3667..4431)
                     /locus_tag="PC512_003479"
     CDS             complement(3667..4431)
                     /locus_tag="PC512_003479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2443178.1"
                     /translation="MAYFNYNDKQCYYNEIGDGTPLLFLHGNTASSKMFNDIIDFYKD
                     EYKVILIDFVGHGKSQMVDKFSADLWFDEAMQVICFLEAMNYKKVNIIGSSGGALVAL
                     NVALERPDLVNKVIADSFEGEVPLESFVQNVKIEREASKQDDGAKAFYIYNQGENWEK
                     VVDNDTEAIFEHYKTIGKFFHKPLETMQPEVLLTGSREDEFVSLISSDFFENTFSLLL
                     EKIKNGKMYLFDKGGHPAILSNGLDFSNVAKKFLEE"
     gene            complement(4587..4820)
                     /locus_tag="PC512_003480"
     CDS             complement(4587..4820)
                     /locus_tag="PC512_003480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443179.1"
                     /translation="MKAEDMKRKVSPIDLERILVTGGVIKHEDSIWLLDFWGNKDIAG
                     ILLMPPTRHVILHLNDCCKWKEYFRTKKKFYRS"
     gene            complement(4894..6387)
                     /locus_tag="PC512_003481"
     CDS             complement(4894..6387)
                     /locus_tag="PC512_003481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDF2443180.1"
                     /translation="MKYTFEKFKLNEKILKSLKSLGYNIPSRVQREVIPKLLKGQNLV
                     VRSKTGSGKTASFAIPLCENINVDYNNIQALIVVPTRELALQVKDEISDIGRLKKVRC
                     SAIFGKQSIKDQIAELKQRVHIVVATPGRILDHINRGSIKLENVKYLVIDEADKMFNK
                     GFVEQMEKILLNLPKEKIVSLFSATIDEEIKYICEKYMLDYSVINIEENESDTNQKTR
                     QIDDKIIKANGREKYILLKELIYSENPKSVIIFCNTKEKVSKLYNKMSKEGFLIRELH
                     ADLSQERRIFVIKDFKNQKFNVLVSSDVASRGIHIDDISLVINYDVPQDKENYIHRIG
                     RTGRKGNSGKAITIVTEKDEKYIENIETYIGYKINELKDIEKSRITHGKILFEEYSKG
                     ILKKVSKRKKVDKNSYNSKDIKLNIESEVVKLYLNAGKKKKIRVLDIVGAFSNIKGIT
                     NDDIGVIEVQDLCSYVDILNYKGDLILKKYKEIPIKKKMVKVKRDIR"
     gene            complement(6715..7257)
                     /locus_tag="PC512_003482"
     CDS             complement(6715..7257)
                     /locus_tag="PC512_003482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF2443181.1"
                     /translation="MKICITVGHSILKGGKSTGVNGIVDEYNYNKKLAPMLAEMLISQ
                     GNTVDVIICPERHFMSEREEFFYRVPKVNSGKYDLLVELHLNKADGTQCGTEVLYYGT
                     EGLEYAKRVSNRLGELFENRGAKKRENLYILRNTNPVAIQIESFFCDNVNDCNKANES
                     GYDYIARLITEGILNKDINM"
BASE COUNT         2711 a         1061 c          818 g         2791 t
ORIGIN      
        1 ttattaataa tctatttata taattatttt tcattcatag tttataagat aattcaataa
       61 aaatctaata gtaaattgtt atttacacat atattgtgat agataaaagc tattcatatc
      121 tgccttaatt ttagtcttaa atttagagtg taaattgaat gcatttagat tataatatat
      181 acagtgaggt aaggtgaata atatgaaaat agatatgata tataaactaa taagaagaaa
      241 tacagaacca tcaagatggt caagaggtgt aaaatattat actaatcaat tagttgatta
      301 tatagacata gatattgatg acctacaaaa taacctgttg acatttcgtg gtggagtcaa
      361 ttctgaagat aattatagct tttattttaa ttcaataact atagatataa agcactttaa
      421 gataattgaa aatgattgta gttgcgctga ctgtcaatca aagggcaaaa gtatttttat
      481 atgtaagcat atagttgcta ttgtgataaa aagcttaaaa caaataaaaa ataaaaaaga
      541 tgttcctcct attctaatag atatattagg tgcagataag gataagcttt ctaatacaaa
      601 ttctaaaacc agcttagatt taagcaagca attactttct ttgttagaca atactaaaag
      661 agaaagggtt aatttagatg tattgataaa tgtggattca aataaagcaa ttgctgaatt
      721 taaaatagga attgataaaa tgtacatttt aaaaaacatt actgaatttg catattcaaa
      781 acttaatgga tatgaattag attttgggaa gaaatttact tacaacccca acactcatta
      841 ttttgctgat gaagatgaga agttagtaga tattatagaa gaatatggga caaatctttc
      901 atacaacttt tcttcatcac attcaaaaaa atttatggag ataaatgcaa gctctttaaa
      961 acaattttta aatgctatta agtacaagga ttttaccctt attttttcta aagaggaata
     1021 tcatccaaag atattaaatg atactctacc tgtaaggttt gattttaaaa atatagaaga
     1081 taaaatagtc ttatattcta aagattcact acctgttcca cttactaaaa aaaatgatgt
     1141 acttttatat gatggcaata tctatttatt atcacataaa aaagctcatg attattcaaa
     1201 aatatatcaa atattatcaa agactaaaga gttaaaattt gataaagagg attctaagga
     1261 tgttttagga ttgctagttc ctagattaaa atctatatct caagaagttc atttagatga
     1321 taacataaaa aataatataa caaaagattt taaatctgag ttctactttg atatgattga
     1381 tggcaacata tgttgtgatg taaagtatat atatgatgat gaagataaaa aatttgtgct
     1441 ccccaacata caaaaggaag ctactattga aaataaactt acttcttcac aatttacaaa
     1501 ggaaaataat cattatgtgt ttaaaggaac tgaccatgac ctatttacat ttttagattt
     1561 acaattagaa tctctaaagg aatttggaga tatatattat tctgagaagt ttaaattgaa
     1621 aaaaatatat aacgcttcat caattcaagc ttcaatcaat cagactaacc agaattacct
     1681 agaatttaat tttaatatat ctgatataaa tccaagagag tacaaggata ttttgaaagc
     1741 ttttcaagaa aaacgtactt tttataaact taaagatgga aactttatag atttatcaga
     1801 aagagaaaca aaagattttt ttgaattagt tgaaaatcta gatataatgg ataaatcaaa
     1861 aaataataaa attcataaaa ataaagctct atatataaat gatgtaatac gtagtaaaaa
     1921 tttaaagttt atagatggta aaaaagaact agacagtata tgtgaaaaat ttagaaattt
     1981 tgatagcata aatttagaaa ttcccgcaaa tttaaatgca aaccttcgtg actatcaaat
     2041 aaatggcctc aattggttta aagttttaga ttattataaa tttggtggta tattagctga
     2101 tgaaatgggt cttggtaaaa caatacagac tattgcattt ttattatcat tatctaataa
     2161 aaaaagtctt attgttacac cgacatcact catttataat tggaaaaatg aatttgaaaa
     2221 gtttgctcca gatataaaag ttttattgat acatggaaat aaaagagata gagaaaaatg
     2281 ttttatggaa ttagaaaatt ttgatgtaat acttacaaca tatggtactc ttagaaatga
     2341 tttagaaaaa tatagtgaaa taaagtttga ttattgtata ttagatgaag ctcaaaatat
     2401 aaaaaatcca gtagctttag taactgagtc tgtaaaaagt ataaatgcag aaaataaatt
     2461 tgcactcact ggtacaccta tggaaaataa tctactagaa ttatggtcta tatttgattt
     2521 tataatgcct ggctatctat atagtaaagc aaagtttcag gaattgttta taaataaaga
     2581 agataatgtt aaaaacctga aaaaattgat aaaacctttt attcttagaa gaagtaaaaa
     2641 acaagttatg aaagaacttc cagataagat tgaaaaaaac ttttttgttg aattgaataa
     2701 agagcagaaa aagatatata gtgtatattc aaaagatata caagataaaa tgaaagataa
     2761 aaatctaaag aaagataaaa tagttatatt ttcttattta actaaactaa gacaactttg
     2821 tttagaccca agtatagtag taaaagatta caataaaaaa agttcaaaaa ttgaaacatg
     2881 tttagaaata cttagggata gtataaacga aaaccacaaa atattattgt tttcacaatt
     2941 tacttctgtg cttaagaaca taagtaagga acttgataag tataaaatta aataccatta
     3001 tatagatggt aaaactaatg ccaaagaaag acttgaactt gtagatgagt tcaataatag
     3061 tatggataaa aaagtttttt taatatcttt aaaagcaggc ggaactggtt taaatcttac
     3121 atctgctgac atggtaattc actttgaccc atggtggaat ccatcagtag aaaatcaagc
     3181 tagtgataga gctcatagat ttggtcaaaa aaattcagta caagttataa aattgattgc
     3241 taaagggact atagaagaaa aaataataaa attacaagaa agtaaaaaag agcttataaa
     3301 tcaatttata aatggagaac tttctaatga aggtgtatta aaaagtctat ctgatgagga
     3361 gataataaac ttatttaact aaattattta atcctacagc ttaactatat aaatttgttc
     3421 taacatttat atagttaagc taaaatatct gaataaataa aatttaatat tgttatttaa
     3481 tcccaacttt acaatctaat gatatctctt tctatacata ttgcatatac aaatgtaata
     3541 acttgactat tagaatattt tgttttaaca atactatttc atcataataa tgaagtatat
     3601 gtacactcac ttttgtaagt tttgcaatcc attttacagt tttcattatt ataaattttg
     3661 gttaaattat tcctctaaaa atttctttgc tacatttgaa aaatctaatc cattcgataa
     3721 aattgcagga tgaccacctt tatcaaacaa atacatttta ccatttttaa tcttttcaag
     3781 aagtaatgaa aaagtatttt caaaaaaatc actagatatt agagatacaa actcatcttc
     3841 tctacttcct gttaaaagca cctctggttg catagtttct agaggcttat gaaaaaattt
     3901 tcctatagtt ttataatgtt caaaaatagc ttctgtatca ttatctacaa ctttttccca
     3961 gttttctcct tgattataaa tataaaaagc ttttgcacca tcatcttgct tagatgcttc
     4021 acgctctatt ttcacatttt gtacaaatga ctctagagga acttctcctt caaaactatc
     4081 tgcaattacc ttattcacta aatcaggtct ctcaagtgca acatttaatg caacaagagc
     4141 tcctccacta ctaccaatta tgtttacttt tttatagttc attgcttcta aaaaacatat
     4201 cacttgcata gcctcatcaa accataagtc agcagaaaat ttatcgacca tttgagattt
     4261 tccatgacct acaaaatcaa ttaatattac tttatattca tctttataaa aatcgattat
     4321 atcattaaac atcttggaag aggctgtatt tccatgtaaa aaaagtaatg gtgtaccatc
     4381 cccaatttca ttatagtagc actgtttgtc gttatagtta aaatatgcca tatatttccc
     4441 ccctttaata tccctatagg tatatattta ttacttatat ttaaaatgac tattccatta
     4501 gccacttaaa aatagtataa cttagaatgt agataaaatc aacattcctt gctaatttat
     4561 ctattgtttg tctaatttat tataatttaa cttctgtaaa atttcttttt tgtacgaaaa
     4621 tattccttcc atttacaaca atcattcaaa tgaagtataa catgacgagt aggaggcata
     4681 agcaaaattc cagcaatatc tttattcccc caaaagtcca acaaccaaat agaatcttca
     4741 tgctttatta ctcctccagt caccaaaatc ctttctaagt caattggaga gacctttcgt
     4801 ttcatatctt cagctttcaa atccttaaca acttctattg tgttttttgc aacttcattt
     4861 cgataacaaa gcaattcatc aatattgact aaattatcgt atatctcttt tcactttaac
     4921 catttttttc tttataggta tctccttata tttttttaat atcaaatctc ccttataatt
     4981 taatatatct acatatgaac ataaatcttg aacttcaatt acacctatat catcattagt
     5041 tatacctttt atattactaa atgcaccaac tatatctaaa actcttattt tcttcttctt
     5101 accagcattt aaatataatt taacaacttc actttctata tttagtttta tatctttact
     5161 attgtaagaa tttttatcaa ctttttttct ctttgatact ttttttagga ttccttttga
     5221 atattcttca aacaaaattt tgccatgtgt aattctactt ttttctatat cttttaattc
     5281 atttatttta tatcctatat acgtttctat attctctata tatttttcat ccttttcagt
     5341 tactatagta attgcctttc cactatttcc ttttctccca gttctaccta ttctatgtat
     5401 atagttttct ttatcttgtg gcacatcata atttattact aaagaaatat catcaatatg
     5461 tattcctctg gacgctacat cactactaac taatacatta aatttttggt ttttaaaatc
     5521 cttaattaca aaaattcttc tttcttgtga taaatctgca tgtaactctc ttattaaaaa
     5581 accttcttta ctcatcttgt tatataattt agatactttc tctttggtat tacaaaatat
     5641 tatcacactc tttggatttt cgctgtatat taattctttt aaaaggatgt acttctctct
     5701 tccatttgcc ttgattattt tgtcatctat ttgtcttgtt ttttgattag tatcgctctc
     5761 attttcttct atatttataa cactgtaatc tagcatatat ttttcacata tatattttat
     5821 ctcttcatct attgtagctg aaaaaagact tactattttc tccttaggta aatttaataa
     5881 tattttttcc atttgttcaa caaaaccttt attaaacatt ttatctgcct catctattac
     5941 taaatacttt acattttcca acttaataga acctctattt atatggtcaa gtattctgcc
     6001 tggagtagct acaacaatat gaaccctttg tttcaattca gctatttggt cttttataga
     6061 ttgtttacca aatatagcac tacatctcac cttctttagt ctccctatat ctgatatctc
     6121 atcttttact tgcaaggcta attctcttgt tggaaccact ataagagctt gaatattatt
     6181 gtaatctaca tttatattct cgcataaagg tattgcaaaa cttgctgtct ttccacttcc
     6241 tgtttttgac ctaactacta agttttgacc ttttaataat tttggaataa cttctctttg
     6301 tactctagaa ggtatattat atcctaaact cttcaatgac ttaagtatct tttcatttaa
     6361 cttaaatttt tcaaatgtat atttcatata ttaccacctt attatattta tcttatctat
     6421 atatttttct acattatatt attataatac aaggttctac tatttttata ttatttatta
     6481 gactgaagat aaaaatatat actctataaa cctatagttt agtagcaaat taattaaatt
     6541 tttatattta aatacctcct taaatatact gataaatcaa tattttcaag gaggtatctc
     6601 ttgtcaataa tcaaactaat ctatcttttg aaagtttaaa ttatactaat acattgtatt
     6661 tttatttata tctaatatta aaaggtatta atcaatacct aaatcaccat aatctcacat
     6721 atttatatct ttattcaata taccttctgt aatcaatcgt gctatataat cataacctga
     6781 ttcatttgct ttgttacaat cattcacatt atcacagaaa aaactttcaa tctgtattgc
     6841 aactggattt gtatttctca atatatataa attttctctt tttttagctc ctctattttc
     6901 aaataattct ccaagtctat tagatactct tttagcatat tctaatcctt cagtgccata
     6961 gtaaagcact tctgtaccac attgtgttcc atcagcttta tttaaatgta gctctactaa
     7021 taaatcgtat ttaccactgt ttacttttgg aactctatag aaaaattctt ctctttctga
     7081 cataaagtgc ctttctggac aaattattac atctactgta ttaccttgac ttataagcat
     7141 ctcagctaac ataggagcta attttttatt ataattgtat tcatcaacta taccatttac
     7201 acctgtactt ttaccacctt ttagtatact atgacctact gttatgcata ttttcattta
     7261 cttttttcac cttcttttaa gccaattttt atataatagt aatataattt taaagttatt
     7321 actaataata atatattaat tgaagaaggt aaaagttctc cgtgattatc atttttttaa
     7381 c
//
LOCUS       DAMJVG010000127         7204 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.132, whole genome shotgun sequence.
ACCESSION   DAMJVG010000127 DAMJVG010000000
VERSION     DAMJVG010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7204)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7204)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7204
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.132"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(22..684)
                     /locus_tag="PC512_003483"
                     /pseudo
     CDS             complement(22..684)
                     /locus_tag="PC512_003483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016440163.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
     gene            complement(844..1380)
                     /locus_tag="PC512_003484"
     CDS             complement(844..1380)
                     /locus_tag="PC512_003484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrpB family protein"
                     /protein_id="HDF2443182.1"
                     /translation="MIGLKCGMVKLLEHQMIWDKSAKDVIILLKSIWDKTAIDIQHIG
                     STSIPSISAKPIIDIVVGVASLEEAKLYLERLEQCGIVFRGQDVPKQLLFAMGDFEKN
                     TRTHHIHVVEWNGVAWNNYINFRDYLNTFTDKAKLYDSHKQKLALQFEDNRKIYTQRK
                     QELINILLEEARLWRINT"
     gene            complement(1453..1866)
                     /locus_tag="PC512_003485"
     CDS             complement(1453..1866)
                     /locus_tag="PC512_003485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003507530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HDF2443183.1"
                     /translation="MKMPKESIDTIMFAPCGMNCMVCYKHCYHKKPCAGCLNGDTGKP
                     EHCRKCKIKDCVCQKGLFYCFECFNFPCKLIKNLEKSYNKRYQASLMENSKFVQQYGL
                     EKFMQKQKERYTCSKCGGIISIHDRECSECQEKVK"
     gene            2332..2949
                     /locus_tag="PC512_003486"
     CDS             2332..2949
                     /locus_tag="PC512_003486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stabilization protein"
                     /protein_id="HDF2443184.1"
                     /translation="MDEKILELLQEMQGSISGIEGTISDMQSNINGIEGTISDMQSNI
                     NGIEGTISSMQGNINGIENTISGMQGTIGDMQGSISGMNGTISDMQGSISSMDGTINS
                     MQDSITDMQVEIKEVNSKLDNMEPDIKDLKTGQVETSSRLDTIQSDVTEIKSDVKINR
                     NTLDTVIKHTSSLVKDTSDIKNDLNNIEIVTSKNSNDIAKLKSVK"
     gene            complement(3557..3736)
                     /locus_tag="PC512_003487"
     CDS             complement(3557..3736)
                     /locus_tag="PC512_003487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDF2443185.1"
                     /translation="MLQTGKQGADKKYLDNMFFVKGYVEELLFLDNNYNIVFSCIVFH
                     HCTNVQNIFCIFWKW"
     gene            complement(3962..4495)
                     /locus_tag="PC512_003488"
     CDS             complement(3962..4495)
                     /locus_tag="PC512_003488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HDF2443186.1"
                     /translation="MQYISYYHSPIGNILLASDNIGLTGLWFENQKYYAYNLDQEHQE
                     KELPIFEQTKKWLDIYFSGKEPDFTPSLHMVGTPFQTTVWKILQQIPYGKTITYGEIA
                     YKVAQQKGISKMSAQAIGGAVGHNGISIIIPCHRVVGTNGSLTGYAGGINRKIKLLSL
                     EKVSVQHYFIPKKGSAL"
     gene            4812..5162
                     /locus_tag="PC512_003489"
                     /pseudo
     CDS             4812..5162
                     /locus_tag="PC512_003489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729451.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(5916..6488)
                     /locus_tag="PC512_003490"
     CDS             complement(5916..6488)
                     /locus_tag="PC512_003490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HDF2443187.1"
                     /translation="MWIYQKTLEHPVNIRQADPRMAKYIMTQLGGPNGELAAATRYLQ
                     QRYTMPTGKSRALLTDIGTEEMAHVEIISSVLYQLIGNCTPEELKAAGLGSNYANFGH
                     GLQPVDSNGVNFTTSYINVFGDSVTDLHEDMAAEQKALATYYQLINLTDDPDLKDILR
                     FLGEREVVHYQRFGEALMDVYEFTECKHQF"
     gene            complement(6550..6813)
                     /locus_tag="PC512_003491"
     CDS             complement(6550..6813)
                     /locus_tag="PC512_003491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein CotJB"
                     /protein_id="HDF2443188.1"
                     /translation="MSLNRRELLERISEYQFACIELNLYLDNNPRDKKALDSYNRYCD
                     KFTQAVCDYESKYGALTNFGYESSEYPWSWISEPWPWDKSFYK"
     gene            complement(6813..7034)
                     /locus_tag="PC512_003492"
     CDS             complement(6813..7034)
                     /locus_tag="PC512_003492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat associated protein CotJA"
                     /protein_id="HDF2443189.1"
                     /translation="MGYLKEDKQDYCCEFARPYINRQIYDDTYNPKTALKRGTLFPEL
                     DLIESNNYNDWLYANPKNRVRAKKGGNMY"
BASE COUNT         2537 a         1224 c          872 g         2571 t
ORIGIN      
        1 agtgtgcgta gctatttttt aatcaaactg gaatacagac tccattccta ggaaattggc
       61 tgaaatatag tctgctgtca aagatgctgt catcacagaa attaaaacag atactgaaaa
      121 gtttttatgg acttcttcaa gtgaaaacat aacacccgcc agtggtgcat gaaaggctgc
      181 tgataatcca gcacttgccc cacaggttaa caggaatttt tcctctgtct tccctcggtc
      241 aagagctcta gaaatacctt tacctgccat agcaccaagc tgaatggaag gaccttccct
      301 tcccaaagca agaccaccca tgagtgataa gaatcctcca ataaattttg ttggcaacac
      361 tcgccaccat acttgtttta ttttccctgt catttccccc tcaagctgag ggataccact
      421 tccagaaatc attggctccc agtccaccaa ctttgataca atccatgcaa gtactgcaag
      481 tactgcaaac caagctatta tttttattgt agaaccttct acaaatttta aaatttggct
      541 aagccaagta ccagcctgcc ctaaaagtat cctgtataaa agcacaatca aaccagccac
      601 agccccaacc ataagtcctt caccaatcaa aattacctga aagtgctctg cccgtttgat
      661 aatatgagat gtatcctttt tcatactgtt cctccttcat ccaataattc tacacaatct
      721 gaatctccaa tgactaaagt catgagtgtg tacagatatt ttttaatcaa caaaaataga
      781 tttttattta ctaaatataa gaaaataatt gctcaatttc tcaataaatg taaatttatt
      841 cttttaggta tttattctcc acagtcgtgc ttcttccagc aaaatattta ttagttcttg
      901 ctttctctgt gtatagattt tacgattgtc ctcaaactgt aatgccaatt tttgtttatg
      961 actatcatag agttttgctt tgtctgtaaa agtatttaga taatctcgaa aattgatata
     1021 attattccat gcaacaccat tccattcaac aacatgaata tggtgagtac gagtattttt
     1081 ctcaaaatct cccatagcaa aaagtaattg ttttggtaca tcctgacctc gaaaaacgat
     1141 tccacattgc tctaaccttt cgaggtataa tttagcttcc tctaaagaag caacacctac
     1201 aacaatatca ataataggct ttgcgctaat actgggaata gaagtgcttc caatgtgttg
     1261 aatatcaatg gcagtcttat cccatatact tttcaataat ataatgacat cttttgcact
     1321 tttatcccat atcatctgat gttccaataa tttaaccata ccacatttta aacctatcac
     1381 tatataccac ctcaatataa tccaccttta tatatattac aattttttct ctcttgataa
     1441 acagtgattt agctatttca ctttttcttg acactcgcta cattccctat catgaataga
     1501 tataattcct ccacatttag aacaagtata tctctccttc tgcttttgca taaacttctc
     1561 taaaccgtac tgctgaacaa atttactatt ttccataagg cttgcttgat atctcttgtt
     1621 ataacttttt tcaagatttt ttatgagttt acaaggaaaa ttgaaacatt caaaacaata
     1681 aaacaaccct ttttgacaga cacaatcctt tattttacac ttacggcagt gttctggctt
     1741 tcctgtatcg ccattcaaac aaccagcaca tggctttttg tgataacaat gcttatagca
     1801 aaccatacaa ttcattccac aaggagcaaa cataatcgta tcaatactct cttttggcat
     1861 tttcataaca ttttactcct ttcaaaaatc caatttgtcg aattgttata tattcatatt
     1921 gtaacataaa aaatagctaa aaaattcatg cactttcatt gccaataaat tttcaaggaa
     1981 atatgaaagt ttaaaactaa gaataaaaag agataaaaag gaagctacta atcaaattat
     2041 tcaaatacaa gtaatcaata taaataactt aaggtatatt taaaagtata tgatattacc
     2101 agcagtttta aatacaaata taaccacaca tgcctcaaaa acacttatta cagtatctta
     2161 gaaacttaga caatacataa gattcattaa taaaaaagtt ctcaatatag atatatttaa
     2221 ccatgttttg aatagcagat aatcatatga ttaaaaatta aatatgacat agcgtttgtg
     2281 gaatataaca cctaaattat gttataataa taaaacagga gtgtgatagt gatggatgaa
     2341 aaaatattag agttattaca ggaaatgcaa ggtagtatca gtggtatcga aggcactatt
     2401 agcgatatgc aaagcaatat caatggtatc gaaggcacta ttagcgatat gcaaagcaat
     2461 atcaatggta tcgaaggcac tattagtagt atgcaaggca atatcaatgg tatcgaaaac
     2521 actattagtg gtatgcaagg cactattggc gatatgcaag gtagtatcag tggtatgaat
     2581 ggcactatta gcgatatgca aggcagtatc agtagtatgg atggcactat taatagtatg
     2641 caagacagta ttactgatat gcaagttgaa attaaagaag tcaatagtaa gttagacaat
     2701 atggaacctg atattaaaga cttaaaaact ggacaagttg aaactagtag tagacttgat
     2761 actattcaga gtgatgttac agaaattaag tcagatgtaa aaattaacag aaatacatta
     2821 gatacagtga ttaaacatac ctcttcatta gtaaaagata catcagatat taaaaatgat
     2881 ttaaataata tagagatagt cacatctaag aattcgaatg atattgctaa attaaaatca
     2941 gttaaataat ataccatagt aaaaaatacc tgaaaatttc acatacttct ttaaagttat
     3001 accaaatttt atacagaaat actgattatc cgacaacaca ctttacttat aaataattta
     3061 ttaaaaaaat actcatttta tcctaaaatt aacacgacta aatgagtctt gatataataa
     3121 taaaaaataa gggagattgg acactaaaaa gttgtgtatc tcccttatat cctataatat
     3181 agttatataa tttttcagcc taaaataaaa gtccatcttt gattaaaaca catcccctta
     3241 tcacttataa aaggataaaa tcttgttttc atttttccat ttatatcttc ttgcttaaga
     3301 gtaataattt tttcttttga tactttaagt gtttggttaa atttaactaa tcgactaagt
     3361 tttgttcaac atctattttt catattttcc aatacttaat ctatttttta taaataattc
     3421 tttcatttct aactcactta cattttttac ataaaacgaa acatataaat ttcaacctta
     3481 tcttgtatgg ttcttaatac ttaatgagta gcttaagtat caatcattat aaatttttcc
     3541 cttacattta acactcttac catttccaaa atatacaaaa tatattttga acatttgtac
     3601 aatgatgaaa tacaatacat gaaaatacaa tattataatt gttgtctaaa aatagaagtt
     3661 cttcaacata acctttcaca aaaaacatat tatctaagta ttttttgtct gctccttgtt
     3721 ttcctgtttg tagcatataa attacttcct ctaaacatat aactactcac atgaaaaaag
     3781 aaaataaact tccaaaatac aagctctaaa aactacctct aaagttgtat aatgtttact
     3841 aggaataagg ttgtataaca tatagtttaa ataatcattt tttaaaattg caagttattg
     3901 ctttcaaaat tagatgtttg tatatcaaat aaatgattaa gaatttctaa atttaatggc
     3961 tttataatgc actccctttc tttgggataa aataatgttg cacagatact ttttctaaag
     4021 ataacaattt tatttttcta ttaattccac cagcataccc agtcaaactc ccatttgttc
     4081 ctacaacacg atgacatgga ataataatag agattccatt atgccctact gcaccaccaa
     4141 ttgcttgtgc tgacatttta gatattcctt tttgttgagc aactttatat gcaatttctc
     4201 cataagtgat tgttttacca tatggtattt gttgtaaaat tttccacact gtagtctgaa
     4261 aaggagtacc taccatatgg agtgatggtg taaaatcggg ttcttttcct gaaaaataaa
     4321 tatctaacca tttctttgtc tgctcgaaaa ttggcaattc tttttcttga tgttcttggt
     4381 caagattata agcataatac ttttgattct caaaccaaag accagttaac ccaatattat
     4441 ctgatgctaa aagaatattt ccaattggac tatggtaata gctaatatat tgcatacaat
     4501 tcctccttat attctgaaaa cttcactcaa atcattagac acttcttttc tatctaccat
     4561 tatgtaaaaa catactaata taatttcctt ctaactacac tttcgttata atatctatcc
     4621 tcatatcata ttagttttat atttacctgc atctgttcat ccttttttcc ctttcccttt
     4681 gatggatata aaattcatac atttaagctt cctactgtat taacttttat agaagtgtat
     4741 cttataattt tatcactaaa tagaccaaaa aaatatcgat atagcatcaa gtaatatcat
     4801 aatactttca aatgggaaaa gtaagaatag gctgtaaaaa agaaaagtat ttttatgtta
     4861 gaaatccagt aaaatcgtta gtagatagaa taacagaaaa cgaacaattt gctatttatc
     4921 attttacaca taaatataat tgacgcaata aagtgttttc tattctacaa cgattaataa
     4981 ggttagaaaa aagtaaaaat gaactgtata tgtatgaagc attagtttct gtttctttcc
     5041 tttggcttat tatgataaaa aatattgttt tgccaccaat aaaacacaaa aatataatta
     5101 atatccatat gcaaaaaatt ttacgttata ttgaaaaata ctattgtttt acattatatt
     5161 gaagggtact attgtgaaaa cttaattttg gagtactatc aagcagtggt aatatcaata
     5221 aatcagagtg ctccagatga tttgaactaa gtttaaatac tataccttat aaatatttta
     5281 ctgagttttg tttattaaaa gcaactcaat ttctaaaagg cacaaatgag ctaataagtg
     5341 acattactat aaaagttgtt tttcatcaaa taatctattt tagtaaatgt tttaaagaaa
     5401 aaacgggata ttctccaaaa gtgtacagaa atataaaaaa agagatatga ttttttattt
     5461 cttttgatta tccaaagagt aaataaaaaa tattgtaaaa aacttactaa caacggcaat
     5521 gctttgaact atggtaatac tttgaacttt tgattggact ttttttgcta aaataatata
     5581 tttaaatagc aaagtaatct gtttaatcaa taaaaaataa gagataaaag aaatcaacta
     5641 aaacttttac ctcttatttt gatagtttat cagagctaat atttacactc tttttatttt
     5701 tgatacttca ttaaaaatga tgcttattct cttttcattt ttaatacttc attagaactt
     5761 atgcttattc tcttttcact tttaattctt cattagaact tatgcttact ctccattcac
     5821 ttttaattct tcattaaaaa tgatgcttac tctccattca cttttaattc ttcattaaaa
     5881 atgatgctta ttctccattc actttcaatt cttcattaaa actgatgctt gcactctgta
     5941 aactcataaa catccattaa tgcttcacca aatctttgat agtgaactac ttccctctca
     6001 cccaaaaatc tcaatatatc tttcaaatca gggtcatcag ttaaatttat taattgatag
     6061 tacgtagcca atgctttttg ttcagcagcc atatcctcat gtaaatcagt taccgaatcg
     6121 ccaaagacat taatataact tgtagtaaag tttactccat tagaatctac tggctgaaga
     6181 ccatgtccaa aattagcata attactacca agtccagcag ccttaagctc ttctggagta
     6241 caattgccta ttaattgata taacactgaa gaaattatct caacatgagc catttcctct
     6301 gtacctatat cagttaaaag tgcacgagat tttccagttg gcatagtata tctttgttga
     6361 agatatctag ttgcagctgc caactcacca ttaggtcctc ccaactgagt catgatatat
     6421 tttgccattc tagggtctgc ttgtcttatg ttaactggat gttccagtgt tttttgataa
     6481 atccacatat tatcttactc ctccttaata tatatttaat aataaatcta attttaaagt
     6541 ttaataattt tatttataaa atgatttgtc ccatggccaa ggttcagata tccatgacca
     6601 aggatattca cttgattcat atccaaaatt agttaatgct ccatatttag attcataatc
     6661 acacacagct tgtgtaaatt tatcgcagta tctgttgtat gaatcaagag ctttcttatc
     6721 ccttggattg ttatctaaat ataaatttaa ttctatacag gcaaattgat attctgaaat
     6781 tctctctaaa agttctcttc tatttaatga cattagtaca tgttaccccc ttttttagct
     6841 ctaactctat ttttaggatt tgcatatagc caatcattat agttatttga ctctattaaa
     6901 tctaattcag gaaataaagt acctcttttt aatgctgttt ttggattgta tgtgtcatca
     6961 taaatttgac gattgatgta tggtctagca aattcacaac aatagtcttg tttatcctct
     7021 tttaaatatc ccattaatta tcctccttaa tttttagaat tttaaaatag cattattttt
     7081 aaaaattgta tactggttct atattataac tggtagtttt aataggtctt taataagatt
     7141 aaatgattaa ataagtatct ttttttctta ttttacctct aaaatttttc taattaatct
     7201 ttca
//
LOCUS       DAMJVG010000128         7195 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.133, whole genome shotgun sequence.
ACCESSION   DAMJVG010000128 DAMJVG010000000
VERSION     DAMJVG010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7195
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.133"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            80..421
                     /locus_tag="PC512_003493"
     CDS             80..421
                     /locus_tag="PC512_003493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator"
                     /protein_id="HDF2443190.1"
                     /translation="MKEENFINVEYEDKRFSINSKEVLYIEKQEYEVKIYTESGNYEV
                     GENAPCIRKLLKEENFFKCSNSYIVNLDKCEFYLSNNCIFVNNNFIRILGSERKKKLK
                     KKLEKLYDYED"
     gene            572..985
                     /locus_tag="PC512_003494"
     CDS             572..985
                     /locus_tag="PC512_003494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1653 domain-containing protein"
                     /protein_id="HDF2443191.1"
                     /translation="MLELKNNLGISERKLKYPCIYKHFKGKYYATMGLSKAIDHIENI
                     CEIYGKENLIQNRNKYKLVIRHTEREEDIYVYRDLDGNFYHKKEEDTNDLVLYKTLYD
                     DTGIFARPLDMFLEKVDTDKYVNSIQEYRFEEVYK"
     gene            1187..1828
                     /locus_tag="PC512_003495"
     CDS             1187..1828
                     /locus_tag="PC512_003495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HDF2443192.1"
                     /translation="MGNTFYIVRHGQTDWNILGKTQGHGNSDLTPQGIEQAKELSEDI
                     GKYSIDYIFSSDLGRAMQTAQILGDKLNIEVQKTEALREMGFGVWEGLLIKEIQKDYS
                     DIYATWRNEPHLVNIPEGETLKIIKERVDAFIKELNEKYDNKNIILVTHSITLRVMLL
                     SFLESGMENIYRIKQDNTALNIVEFKDYGPVIVKMNDTSHIKNHVKINNSALE"
     gene            1852..3105
                     /locus_tag="PC512_003496"
     CDS             1852..3105
                     /locus_tag="PC512_003496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDF2443193.1"
                     /translation="MSKVIVVGGGASGMMAALSASKNNNEVILVERNGELGRKLRATG
                     GGRCNFTNNREIEDFFDKVVSNKKFLYSSFYTFTNKDLISYFESRNLEYKIEEENDHK
                     VYTKNDKSIEVIEVLNKDLLNHNVKIMYNKKVIDIITEEIALKDDSNKDKSKYLIKGI
                     ILDNGDKILGDKVIISTGGVSYSKTGSDGSMYKILKKHGHTLNKLYPALVPLTIEEKW
                     IKDLQGISMKNVEISCKIKKRKISKSGDMLFAHFGITGPCVLIMSSYINKIIEKEKVE
                     LNIDFLPNLSTDEISSIIRAFPNKNVLNNLKQILPQNFLKEIFSLLSLVDKKASDLSK
                     ADEIRIIEYIKNMKLTCNGTTGINTGMVTSGGISVKEINSSTMESKLVKNLFFTGEVI
                     DIDAETGGYNLQIAFSTGYLAGISV"
     gene            3151..3801
                     /locus_tag="PC512_003497"
     CDS             3151..3801
                     /locus_tag="PC512_003497"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HDF2443194.1"
                     /translation="MGNLVIAVDGPAGAGKSTIAKIVAKKLNINYIDTGAMYRAVTYK
                     CLKSGIDVNNEKEVIQIAENSDIDFKDNNIYLDKEVINEEIRTIEVSNNVSNVAKIKE
                     VRQLMVEVQRKIGMKNSVILDGRDIGSYVFPDADYKFFLVATPEERGNRRYKELCNKG
                     YNTTLEEVIEDIIRRDEIDSNREFAPLVKANDALEIDTTGKTIEEVVEEVVSKINL"
     gene            3852..4448
                     /locus_tag="PC512_003498"
     CDS             3852..4448
                     /locus_tag="PC512_003498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HDF2443195.1"
                     /translation="MNFYRFVINIFKGFSKIFFKYEVIGAENIPDRGNIVIASNHKSN
                     LDPIFLAAAIENREIAAIAKKELFKVKPLGFILKKLHVMPINREKPDVSTIKTILRSV
                     RDGYVLGIFPEGTRIKGDSFGKAKAGLSVFTIKSKSKVVPVSIISKYKLFSKVIVYIG
                     EPISFEEHFKEKLSNDDHERISQEILEVIKQNYFKYSK"
     gene            4461..5300
                     /locus_tag="PC512_003499"
     CDS             4461..5300
                     /locus_tag="PC512_003499"
                     /EC_number="1.17.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="HDF2443196.1"
                     /translation="MNIKIAKNAGFCFGVKRAMKMAWDEVEKNDSGIYALGPLIHNKQ
                     AVAKYEEKGLKTVNEIDTIPNHENMIIRSHGVPENIYKEAKDKKLKIVDTTCPFVKKI
                     HTVVSEYHNKGYEIIVIGDMKHPEVIGINGWCENSAIIIKTLEQMENMEFDNSKRYCL
                     VAQTTINPELYISIVNKLSDKLEEIVFNDTICSATKTRQESAKELAKKVDCMIVIGGK
                     HSSNTQKLVKVCEDLVPTFAIETKDELDVNTLKKYKNLGITAGASTPNWIIEEVVTFL
                     ENL"
     gene            5545..6699
                     /locus_tag="PC512_003500"
     CDS             5545..6699
                     /locus_tag="PC512_003500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenic efflux protein"
                     /protein_id="HDF2443197.1"
                     /translation="MEMLISASEEAFLHVGSMIGFFILLFGYINYKTSGNFTNIISKN
                     RKFQPLIGALIGAIPGCGGSLAIMPLYINGKLSFGAIIASLIASMGDAAFVLISSNIK
                     MYFFVTIVSTITGIITGQLVDYFKLEEKLGLKNRRKSDKYDISKNNPKENKEQHNHDE
                     IILDTLAKSHGNTNRLAFIITHGKGYKIYIGIIVIGFIFMSLAHSGLNLPIIEKLHSL
                     EEVIAVIGILFSIIYMWCFKKVFKNSNQKEEENKKISLREMLIHSVGEISFVITWIFI
                     AYLIYDLIILILGGDEYLVKLVLSTGVISVFIGAGLGLIPGCGIQIVLMSFYLKGTIP
                     LGAVIANSISQDGDALFPLLAMDKKSSLWAMIITTIPAILVGMIVYAFLG"
     gene            7005..7181
                     /locus_tag="PC512_003501"
                     /pseudo
     CDS             7005..7181
                     /locus_tag="PC512_003501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728625.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
BASE COUNT         2990 a          675 c         1258 g         2272 t
ORIGIN      
        1 gtcttacata tatttccgat agattatatt gataaaaaac actaaaatta aattaataaa
       61 agtacttgga gggatggaaa tgaaagagga aaattttatt aatgttgaat acgaggataa
      121 acgtttttca attaatagta aagaagtttt gtacatagaa aagcaagagt atgaagtaaa
      181 gatttatact gaaagtggta attatgaagt tggagaaaat gctccttgta taagaaaact
      241 attgaaagaa gaaaattttt tcaaatgcag taatagttat attgtaaatc tagacaagtg
      301 tgaattttat ctcagcaata attgtatttt tgtgaataat aattttataa gaattttagg
      361 ttcagaaaga aaaaagaaat taaaaaagaa attagaaaaa ttatatgatt atgaagatta
      421 atattgggag gctgtatttt atacagcctc tttatttatt gattgtatta ttaataaatt
      481 ttaaattatg ataaaatata aaacaagtaa cttatttcag aataaaatac tttttaaaag
      541 aaagggacga gatatgggag attataataa aatgcttgaa ttaaagaata acttaggtat
      601 cagtgaaaga aagttaaaat atccttgtat ctataaacat ttcaaaggga aatattatgc
      661 tacaatgggt cttagcaagg ctattgatca tatagaaaac atatgtgaaa tatatggtaa
      721 agaaaattta atccaaaaca gaaataaata taaattagtt attagacata ctgaaagaga
      781 agaagatatc tatgtttata gggatttaga tggaaacttt tatcataaaa aagaagaaga
      841 tactaatgat ttagttttat acaagacctt atatgatgat acaggaatat ttgcaagacc
      901 tttggatatg tttttagaaa aagtagatac agataagtat gtcaattcaa ttcaagaata
      961 cagatttgaa gaagtatata aataatataa gagaaatatg tttataaatt tagaaaaatt
     1021 ctttaacagt acaataattt gcagaaatac aaatgagatt tattgtaaat aatatgttag
     1081 attagattat aaaatagaaa caaagtaaag tattatatga tataattaag ttttgagaag
     1141 tgataattta tatttaataa aaaataggca tatattagga ggacatatgg gaaatacttt
     1201 ttatatagta agacatggac aaacggattg gaatatattg ggaaaaacac aaggtcatgg
     1261 taattctgac cttacgcctc aaggtataga acaggcaaaa gaactttctg aagatattgg
     1321 caagtattca attgattata tttttagtag cgaccttggg agagcaatgc aaacagctca
     1381 aattttagga gataagctca atattgaagt tcaaaaaact gaggcactta gagaaatggg
     1441 attcggagtt tgggaaggcc ttttaataaa agaaattcaa aaagattatt cagatatata
     1501 tgcaacatgg agaaatgaac cacacttagt aaatatacca gaaggcgaaa ctcttaagat
     1561 tataaaggaa agagtagatg cttttataaa ggaactaaat gaaaaatatg ataataaaaa
     1621 tataattctt gttacacatt caattacatt gagggttatg ttgttgtcat ttttagaatc
     1681 aggtatggaa aatatatata gaattaagca agataatact gctttaaata tagtagaatt
     1741 taaagattat gggcctgtta tagtaaaaat gaatgataca agtcatataa aaaatcatgt
     1801 aaagataaat aattctgcac tggagtagga atcaattata aggagaaatt tatgagtaaa
     1861 gttatagtag ttggtggagg agcttctgga atgatggcag ctttgtcagc ttcaaaaaac
     1921 aataatgaag taatattagt tgagagaaat ggagaattag gaagaaaact tagggcaact
     1981 ggtggcggta gatgcaattt taccaataat agagagatag aagatttttt tgataaagtt
     2041 gtcagtaata aaaaatttct ctatagtagt ttctatacat ttacaaataa agaccttatt
     2101 tcgtattttg aaagtagaaa tttggaatat aagattgaag aagaaaatga ccacaaagta
     2161 tacactaaaa atgataaatc tatagaagta atagaagtat taaataaaga tttactcaat
     2221 cacaatgtaa agataatgta taataagaaa gttatagata ttataactga agaaattgct
     2281 ctaaaagatg attctaataa ggacaagtca aagtatctaa taaaagggat tattttagat
     2341 aatggagata aaatactagg agacaaggtt attatatcaa ctggaggagt gagttattca
     2401 aagacgggtt cagatggttc aatgtataag attcttaaaa agcatggaca tacattaaac
     2461 aaactatatc ctgctttagt tccacttaca atagaggaaa aatggattaa agatttacaa
     2521 ggaatatcca tgaagaatgt ggaaatatct tgtaagatta agaaaaggaa aatatcaaaa
     2581 tctggagaca tgctatttgc ccattttggg ataacaggac cttgtgttct tataatgtct
     2641 tcttatatta acaagattat tgaaaaggaa aaggtagaat taaatataga tttcttacca
     2701 aatttaagta ctgatgaaat ctctagtata atcagagcat ttccaaataa aaatgttcta
     2761 aataatctta agcaaatact acctcaaaat ttcttaaaag agattttttc tctattatct
     2821 ttagttgata aaaaggcaag tgatttgtct aaggcagatg aaattagaat tattgagtat
     2881 ataaaaaata tgaagctaac ttgtaatggg actacaggta taaacactgg tatggttact
     2941 tctggtggta tttcagttaa agaaattaat tcttctacta tggaatctaa attagttaag
     3001 aacttatttt ttacaggtga agtaattgat atagatgcag aaactggtgg atataattta
     3061 caaatagcat tttcaactgg atatcttgcg ggtataagtg tataaatata attttttaat
     3121 aattaaatat gaataaatag aggtgtatat atgggtaatt tagttatagc tgtagatggt
     3181 ccagcaggag ctggaaaaag tacaatagcc aagatagtag caaaaaagct aaatataaat
     3241 tatatagata caggtgctat gtacagagca gttacttata agtgtttaaa aagtggtatt
     3301 gatgtcaata atgaaaaaga agttattcaa atagctgaaa attcggatat agattttaaa
     3361 gataacaata tatatttgga caaagaagtt ataaatgaag aaataagaac aatagaagta
     3421 agcaataatg tttctaatgt agcaaaaata aaagaagtaa gacagttgat ggttgaagtt
     3481 caacgaaaaa taggaatgaa aaattcagta atactagatg gtagagatat aggttcatat
     3541 gttttcccag atgcagatta caaattcttt ttagtagcta ctccagaaga aagaggaaat
     3601 agacgctata aagaactttg taataaagga tataatacta ctttagaaga agtaattgag
     3661 gatataataa gacgagatga aattgattca aatagagaat ttgcaccatt ggtaaaagct
     3721 aatgatgcac tagaaataga tactacagga aaaactatag aagaagttgt agaagaagtt
     3781 gtatctaaaa taaatcttta gttttttatg catcataatg aaaataaatg tagtgttgaa
     3841 gggagataaa cgtgaatttt tatagatttg taataaatat ttttaagggt ttttctaaaa
     3901 tattttttaa atatgaagtt ataggtgcag agaatattcc agatagagga aatatagtaa
     3961 tagcatcaaa tcataaatcg aatcttgacc ctatattctt ggctgctgcc atagaaaata
     4021 gagaaatagc tgcaattgca aagaaagaat tgtttaaagt aaaaccattg ggatttatat
     4081 taaaaaaatt gcatgttatg cctataaata gagaaaaacc agatgtatct acaataaaaa
     4141 ctattttaag gtcagttaga gacggttatg tattaggaat atttccagag ggtactagaa
     4201 taaaaggaga ttcttttggt aaggctaagg caggtctttc tgtatttaca ataaaaagta
     4261 aatctaaagt tgttccagta tcaataatat ctaaatataa actttttagt aaagtaattg
     4321 tatatattgg agaaccaata tcatttgaag aacattttaa ggaaaaattg agtaatgatg
     4381 accatgaaag gatatcacaa gagattttag aagtgataaa acaaaattac tttaaatatt
     4441 caaaataagg gggtaaagtt atgaacataa aaatagcaaa aaatgctggc ttttgttttg
     4501 gagtaaaaag agcaatgaaa atggcatggg atgaagttga aaaaaatgat tctggcatat
     4561 atgctttagg tcctcttatt cataacaagc aagcagtagc aaaatatgaa gaaaaaggtc
     4621 ttaagactgt gaatgaaatt gatacaatac caaatcatga aaatatgata ataaggtctc
     4681 atggagttcc tgaaaatata tataaggaag ccaaagataa aaaattaaaa attgtggata
     4741 ctacatgtcc atttgtaaag aaaatacata cagtagtaag tgaatatcat aataaaggct
     4801 atgaaataat agttattgga gatatgaagc atccagaagt tataggtata aatggatggt
     4861 gtgaaaattc agctataata ataaagacct tagaacaaat ggaaaatatg gaatttgata
     4921 actccaaaag atattgtctt gttgcacaga ctacaataaa tccagagttg tatataagta
     4981 tagttaataa actatcagat aaattagaag aaatagtatt taatgataca atttgttcag
     5041 ctacaaaaac aagacaagaa tcagctaaag agttagctaa aaaagttgat tgtatgatag
     5101 ttataggagg taaacacagt tcaaatactc aaaagttagt aaaggtttgt gaagacttag
     5161 taccaacttt tgcaatagag actaaagatg aattggatgt aaatacgctt aaaaaatata
     5221 aaaatttggg tattacagca ggggcatcta cacctaattg gataatagaa gaagttgtaa
     5281 cattccttga aaatttataa tttgataggt aataaaaata ggtggacatt gttataattt
     5341 atcataatat ccacctttga tttcatatta catgtggtaa atagataacc taatatcaaa
     5401 aagtgtgtat cttaagatga aaaactaaga gtataagatg cgcacttttt aatattagaa
     5461 attcaaaaga aatattgata ttgattatca atagaaaata gaatataata taattgttgc
     5521 aaaattagtc taggaggtaa attaatggaa atgttgatat ccgcttctga agaggcgttt
     5581 ttacatgtag gttctatgat tggatttttt attttgttat ttggatatat taattataaa
     5641 actagtggaa attttactaa tatcatatca aaaaacagaa aatttcaacc cttaataggt
     5701 gctttaattg gagctatacc aggttgtggc ggaagtttgg caataatgcc attgtatata
     5761 aatggaaaat taagctttgg agcaataatt gcaagtttaa tagctagtat gggagatgca
     5821 gcatttgtac ttatttcatc aaatattaaa atgtattttt ttgtcactat agttagtaca
     5881 attacaggaa taataactgg acaattagtg gattacttta aactagaaga aaaattaggg
     5941 ttaaaaaacc gtagaaaatc agataaatat gatataagta aaaataaccc taaagaaaat
     6001 aaagaacaac ataatcatga tgaaataatt ttagacactc tagctaaatc tcatggaaat
     6061 acaaatagac ttgcatttat aataacacat ggaaagggat ataaaattta tataggaatt
     6121 atagtaatcg gttttatatt tatgtcactt gctcactctg gacttaatct tcctataatt
     6181 gagaagttac attcattgga agaagtaata gcagtgattg gaatattatt ttcaataatt
     6241 tatatgtggt gttttaaaaa ggtatttaaa aattctaatc aaaaagagga agaaaataaa
     6301 aagatttctt tgcgagaaat gcttatccat tctgttggag aaatatcatt tgtaattaca
     6361 tggattttta ttgcatatct tatttacgat ttgataatat taattttagg tggagatgaa
     6421 tacttagtta aattagtatt atcaacaggt gtaataagtg tatttatagg tgcaggtctt
     6481 ggacttattc caggttgtgg gatacaaatt gtgcttatgt cattttattt gaagggaact
     6541 ataccacttg gtgcagtgat agccaactct atttctcaag atggagatgc acttttccca
     6601 cttttagcaa tggataaaaa atcttcttta tgggctatga ttattactac tataccagca
     6661 atacttgtag gtatgatagt ttatgcattt ttaggttaaa tataattatg aataaagaag
     6721 tattaaaaaa ataataaagc acataaattt atttataaga atagtgaaga ttaaatataa
     6781 aaataaaaaa ttcaatatga attaaattat tgcttaaata ttaatgagaa catgggagat
     6841 aatattattc ctcatgttct ctctatttaa ttaaaggaat tatggaacaa atttcaagtg
     6901 atactttcta tcaaaactca tatataatat atattaataa attaaactat aatacgtaat
     6961 acagtcagta tattgatata aaaaacttag gaggagttgt aaaaatgggt aatttaaaaa
     7021 gacagtgtga tgtttcaagt ggaagagaaa aagctgacat tgtactaaaa aatgggacaa
     7081 tcataaatgt atttacagaa gagttaataa caggagatgt agcaatagta ggagacacta
     7141 tcgttggaat tggcgattac aagggcaatg tagaaattga ttaaaaaata gctac
//
LOCUS       DAMJVG010000129         6713 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.134, whole genome shotgun sequence.
ACCESSION   DAMJVG010000129 DAMJVG010000000
VERSION     DAMJVG010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6713)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6713)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6713
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.134"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            401..1675
                     /locus_tag="PC512_003502"
     CDS             401..1675
                     /locus_tag="PC512_003502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HDF2443198.1"
                     /translation="MQFMDVSKYIEGANLKVKTKNGETVKRIYFNNSATPLVLKNVVD
                     NLNCEIPWLTYINAPGIISEKNTLKYENVRSTILKLIDGDEEKDSVIYVKNATEGINF
                     LAKFFKDENPDKFVITTAMEHMANYLPFKVNFPTKVVGITEKGELDLCQLENILKNYA
                     GNVSLVTVTGASNVTGITTPIYEIARIAHKYGAKILVDIVQVIQHKPFSMMPHECDEH
                     IDFVVFSAHKCYSPLNGGALVGPKKFFEKFNPVLYGSGSTKFVNDNKILYANVPQRFE
                     AGYPEYFGTLAMGKALNTLNKIGLNRISKYERELFLYAKEEMSKIPNIIIYGDKSNNV
                     IIPNISFNISNMYYKDVAKYLVDNFGIETGAGVVGADIYVQKLLGINPKEAYVRFMRE
                     NPVGLVRISLGMYNTFDEVDSFIHAIKTLAFK"
     gene            complement(1882..2199)
                     /gene="trxA"
                     /locus_tag="PC512_003503"
     CDS             complement(1882..2199)
                     /gene="trxA"
                     /locus_tag="PC512_003503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HDF2443199.1"
                     /translation="MVKIINNNEFINEVENKDGLVVVDFFATWCGPCKMLSPIYEALG
                     NEMVEKANFLKVDIDQSIELAQKFEVSTVPTMLIFKDGKPVDRLIGFMPKENLKNKIE
                     SYM"
     gene            2466..3218
                     /locus_tag="PC512_003504"
     CDS             2466..3218
                     /locus_tag="PC512_003504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrmB family transcriptional regulator"
                     /protein_id="HDF2443200.1"
                     /translation="MDNIINELQNIGFTKYESQIYISLLKESPLTGYEISKLSGVPQS
                     KVYENITKLLNNNIIINVGTDPIKYIPINPNELLKNKKKEFDNSMDNLKNSLQILNKS
                     KSVEYVLNIKGDKNILKKAIEMIKNAKQEIIISCPYEEILELKKELLIAYKKNINIEI
                     LLLENKSLKGLDNIHIHGGNKTTLENKMLYKGIILIVDNDEILTGNLSEGSEAISIWT
                     KNSNILYIGVQYIKHEIYISEQIKGGYKNEQN"
     gene            3205..4086
                     /locus_tag="PC512_003505"
     CDS             3205..4086
                     /locus_tag="PC512_003505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HDF2443201.1"
                     /translation="MNKIKIKQVDAFTTIPFGGNPAGVVTDASNISDEIKQNVAKEMN
                     LSETAFVSESNIADFKVQFFTPGLEVDLCGHATIGTFHALLEEGKLNTNKSIFYQETK
                     AGVLSVELKKINNENIFMMEQNTPEFENLDNCRKELAQMIGVHEDRLLEYPIIKVNTG
                     LWWLVFGLKSLDDLKNISPDLNKIKKFSGDNNIIGITPFCIETIDKKCDYHLRSIAPY
                     VGVTEDPVCGTGNACVSSYIVHHNILDKTSFIGEQGNFINRPGKVYVNITRENNDITS
                     VKIGGSAYTILSGEIMY"
     gene            complement(4312..5667)
                     /locus_tag="PC512_003506"
     CDS             complement(4312..5667)
                     /locus_tag="PC512_003506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HDF2443202.1"
                     /translation="MSSTVKKKGKFPMGFYICSTTFSFERAAYYASKYLIYIFLTTAI
                     VHGGLGIDKGQAAIMQANLVAFTYLAPIIGGYISDRWIGARYTIPIGMLIMGVGYYLG
                     SIATTVSMVNAMIILVSIGTAFFKGNVSAVNGQLFDSQEELDTAFSVQYSFVNIGSFI
                     GTIAVGILYLKTFAKNGVLGFSQCFFIAAVLCVIGAIWFIYGWRFLGNAGKRPFKEGV
                     VAEKIEEKDKSPLTSMDKKRIWAIILISFFSVIFWVFWYLTYLAVYDYGAAFVNMNVG
                     GFDVPLAWFDSLNSLVCIVLGPVLGALWFKLASRPQGDMSLFKKTGLGLIFLGLAFLM
                     LVGAEFSRGVGAPETAKASILWIIMFGILLSLGEMLFSPLGNSFVSKYAPKKLLGVLM
                     GVWTFATFIAGKGYGYIYAFTLKFDMIKVYTIIPVILFVAAILLFLSDKTLSRLVEDD
                     K"
BASE COUNT         2590 a          953 c          836 g         2334 t
ORIGIN      
        1 aaaatctttt tttctaatta tatacaatat attttccatt atgttctaat caatttcttt
       61 actattttta caactttatt agtcatattc ataattattt ctaattagtg tttaacattt
      121 tatgtaaaat ttataaaaaa atgtatataa attaaaataa gtgactatac taaaaatatg
      181 atacggataa acaataagtt caacctatct cccccaaaat caagtgagct acagtttccc
      241 ccaactgtag ctcattttcg tgtaatttaa taaacatctc aacaagaatt aattaacaaa
      301 accccttata aaaacataac atatattaaa caagctcttg attaaaactt gagctttttt
      361 aataaaaaac agaatagttt attagataag gggttttttt atgcaattca tggatgtatc
      421 taaatacatt gaaggtgcaa accttaaagt taaaactaaa aatggtgaaa ctgttaaaag
      481 aatatatttt aacaactctg ccactccatt agttttaaaa aacgtagtgg ataacttaaa
      541 ctgtgagatt ccttggctta cttatattaa tgctccagga ataatctcag aaaaaaatac
      601 tttaaaatat gaaaatgtac gctctactat cctcaaactt attgatggag acgaagaaaa
      661 ggattctgtt atttatgtca aaaatgctac agaaggaata aacttcttag caaaattttt
      721 taaagatgaa aatccagata aatttgttat taccacagca atggagcata tggctaatta
      781 cctgcctttt aaagttaatt ttcctacaaa agttgttgga attacagaaa aaggagaact
      841 tgatttatgt caattagaga atatacttaa aaattatgct ggtaatgtat ctctcgttac
      901 agttacagga gctagtaatg tcacaggtat aaccactcct atatatgaaa tagcaagaat
      961 agctcataag tatggtgcaa agatattggt ggatattgtg caagtaattc agcataaacc
     1021 tttttcaatg atgccacatg aatgtgatga gcatatagat tttgttgttt ttagtgctca
     1081 taaatgttat tctccactaa atggaggagc tctggtagga cctaaaaaat tctttgaaaa
     1141 atttaatcct gtactatatg gctcaggttc taccaaattt gtaaatgata acaaaatact
     1201 atatgcaaac gtaccccaac gttttgaagc aggataccca gagtattttg gaactcttgc
     1261 aatgggaaaa gcactgaaca ctttaaataa aattggtcta aacagaattt caaaatacga
     1321 aagagaatta tttttatatg ctaaagaaga aatgagtaaa atacctaata taataatata
     1381 tggagataaa tcaaataatg taattatccc aaatatatct tttaatataa gtaatatgta
     1441 ttacaaagat gtagcaaaat atttagttga taactttgga atagaaactg gagctggagt
     1501 agtaggtgca gatatttatg tacaaaaatt attaggtata aatccaaaag aggcatacgt
     1561 cagatttatg agggaaaatc ctgtaggtct tgttaggata agcttaggaa tgtacaatac
     1621 ttttgatgag gtggatagct ttatacatgc tattaaaact ttggctttta aataagattt
     1681 ttctattctt ttttatcaat aaatagagag tagttttgtt ttcacaaaaa aacaaattat
     1741 atcaacagtc aatttcatta gcaattagac actcatttgt aactatacaa actattttac
     1801 actatacaaa caaaaaactc attacaatga gtttttttgt ttatatatga gatttatttt
     1861 aattacttca atttacttta attacatata tgattcaatt ttgtttttta aattctcctt
     1921 aggcataaaa cctattaatc tatctacagg ttttccatcc ttaaatatta gcatagttgg
     1981 tactgtagat acttcaaatt tctgagctaa ttctatactt tggtctatgt ccaccttcaa
     2041 gaagtttgct ttttcaacca tctcatttcc taaagcttca tatattggtg atagcatctt
     2101 acaaggtcca caccaagtcg caaagaaatc tacaactact aaaccatctt tattttctac
     2161 ttcatttata aattcattat tatttattat ttttaccata atatacatct cctttattat
     2221 cttcttgata ttaatatact acgccctata taacagttca attaggcact tttttgtaac
     2281 cgcctatttt taatagattt aatattatga taaatagatt tataagatta aatatttatg
     2341 agactaaata tttctaatat attttatttt tttcttaata tagttgacat tttttccctt
     2401 aaattataaa atcaaattaa taactacata ggtagttact aatcttttat caaaggagtt
     2461 tctatatgga taatataatt aatgaattac aaaatatagg atttactaaa tacgaatctc
     2521 aaatatacat atcattatta aaggaaagcc ctttaacagg atatgaaata agtaaattat
     2581 caggtgtacc acaatcaaaa gtctatgaaa atataacaaa gctattaaac aataatataa
     2641 ttatcaatgt tggaactgac cctattaagt acataccaat aaaccctaat gaattattaa
     2701 aaaataagaa aaaagaattt gacaattcta tggataatct aaagaatagc ttacagatat
     2761 taaataaaag taaaagtgta gaatacgtat taaacataaa aggagataaa aatatattaa
     2821 aaaaagcaat agaaatgata aaaaatgcaa aacaagaaat tataatttct tgcccttatg
     2881 aagaaattct tgaattaaaa aaagaactcc taattgctta caaaaaaaat attaatattg
     2941 aaatactact tttagaaaac aaaagtctga aaggtcttga taatattcat attcatggag
     3001 gtaataaaac tacacttgaa aataaaatgc tttacaaagg aattattttg attgtagata
     3061 atgatgaaat attgacagga aacttatcag aaggcagtga ggccatttca atttggacaa
     3121 aaaactctaa cattttatat attggagttc aatacataaa acatgaaatt tatatttcag
     3181 aacaaataaa aggaggttat aaaaatgaac aaaattaaga ttaaacaagt tgatgctttt
     3241 acaactatac cttttggtgg aaatcctgct ggtgtcgtta ctgatgcctc taacatttct
     3301 gatgaaatta agcagaatgt ggctaaagaa atgaatttat cagaaactgc atttgtttca
     3361 gagtcaaata ttgcagattt taaagtacaa tttttcacac caggtttaga agttgattta
     3421 tgtggtcatg caacaatagg tactttccat gcacttttgg aagaagggaa gcttaatact
     3481 aataagagta tattttatca agaaacaaaa gctggtgtat tatctgtaga gcttaagaaa
     3541 ataaataatg aaaatatatt tatgatggaa cagaatacac ctgaatttga aaatttagat
     3601 aattgcagaa aagaacttgc acaaatgata ggtgtgcatg aagatagact tcttgaatat
     3661 cctattataa aggtaaatac tggactttgg tggcttgtat ttggtctaaa atctttagat
     3721 gatttaaaaa atatctctcc agatttaaat aaaatcaaaa aatttagtgg tgataataat
     3781 ataattggta taactccatt ttgtatagaa actatagata aaaagtgtga ctaccattta
     3841 agatctatag caccatatgt tggagttaca gaagaccctg tatgtggaac tgggaacgct
     3901 tgcgtatcat cttatatagt acatcacaat attttagata aaactagttt tattggtgag
     3961 caaggtaact ttataaacag acctggaaag gtatatgtaa atataactag agaaaacaat
     4021 gacataactt ctgtaaaaat tggaggaagt gcttatacta ttttaagtgg tgaaattatg
     4081 tattaatccc atacctaata aaaacaaata aaaatactag ctaactaaag ctagtatttt
     4141 tatttgttat ttttatttaa taatcatact ctaacaaata ttataattat atatatcata
     4201 atattgtatt tagaagtaaa attttatttt tattattaat tagttataaa tcaatctaat
     4261 acaacataat tacagtagat taacctataa aacataataa ttgcttacta attatttatc
     4321 atcctcaaca agtctactta atgtcttatc agataagaat aataatatcg ctgcaacaaa
     4381 tagtattact ggaattatag tatatacttt aatcatatca aatttaagag taaatgcata
     4441 tatatatccg tatcctttac cagctataaa agtagcaaat gtccatactc ccataagaac
     4501 acctagaagc ttcttaggtg catacttact tacaaaagag ttaccaagtg gtgagaataa
     4561 catttcacca agacttaaaa gaataccaaa catgattatc catagtatac tagctttagc
     4621 agtttcagga gctccaaccc ctcttgaaaa ttctgcacca acaagcatta agaatgcaag
     4681 acctaagaat attaatccaa gacctgtctt tttaaataaa ctcatatctc cttgtggtct
     4741 actagcaagt ttaaaccata atgctccaag aactggtcct aatactatac atacaagtga
     4801 atttaatgag tcaaaccaag caagaggaac atcaaatcct ccaacattca tgtttacaaa
     4861 tgctgcacca taatcataaa ctgcaagata agttagatac cagaataccc agaaaattac
     4921 agagaagaat gatataagta taatagccca aattctcttc ttatccatgc ttgtaagagg
     4981 agacttatct ttttcttcaa ttttttcagc aactacacct tctttaaaag gtctctttcc
     5041 tgcattccca aggaatctcc atccatatat gaaccatatt gcacctatta cacaaagtac
     5101 agctgctata aagaaacatt gagaaaatcc aagtacacca ttttttgcaa atgttttaag
     5161 gtaaagaata ccaactgcta tagtaccaat aaaagaacct atattaacaa aagaatactg
     5221 tactgaaaat gctgtatcaa gttcttcttg actatcaaaa agctgtccat ttaccgcaga
     5281 tacgttacct ttaaagaatg cagtaccaat tgaaactaag attatcattg catttaccat
     5341 agaaactgta gttgcaatag aaccaagata gtatcctact cccatgataa gcatacctat
     5401 aggtatagta tatctagctc ctatccatct atctgatata tatcccccaa ttataggtgc
     5461 aaggtatgtg aatgcaacaa ggttggcttg cattatagca gcttgtcctt tatctattcc
     5521 aagaccacca tgaactatag ctgttgtaag gaatatatat attaagtact ttgaagcata
     5581 atatgctgct ctttcaaatg agaaagttgt tgagcagata taaaatccca taggaaattt
     5641 acccttcttt tttactgttg agctcataat tttaaatcct ttcttaattg tatttttatt
     5701 ttttacgttt tgtccaaatt ctttctttta tgaaagatat aatattatta ttttgtaaaa
     5761 caatttgtaa ttattattaa gataattgcg catttatttg tagagtacat attctcatgg
     5821 aataaaatta atacacttct taatcataaa tttaaattat ataaattcac tattttcaga
     5881 tatagttata aattaatata ttctcatcta ataccatgaa aaaaccttcg ccatatgcaa
     5941 ttcttatttt ttacgtgata gtattttaca aactaaaatc ccccttttgt agcaacttat
     6001 gtaattacat tttagtgctt ttttaaagga gtctcgaata aagcaacata tattttgttc
     6061 aaataatgtt tttatttatt ttttaaattt atatattact tcactcaacc aattctcaac
     6121 ttaaataact aaactactat ctattcacag attaggctta tttcttacac attagtttat
     6181 aataaacact gtgaatctaa acataaaaac tgttatttta aagtaattac ccatatattc
     6241 gctttgatac tatttattga ggttatactc tttatgtata atatattatt tataaaatac
     6301 ctcaaaatat attattcata aaatacctca aactgaaaac tttttcacga atatttattt
     6361 ttcacctccc cttttttatt tcaccatgta aatcgtacca taaatatgca cttatatgca
     6421 agaaaaaaat ctattaatcg acagtaaata attagaaaaa ttcaaattat atttatcaag
     6481 tatattatat aaaatatttc ctatgaaaat ataaattaaa ttaatgttca gaattgtttt
     6541 tagatatgaa atcttgattt ttttattact ttacttattt gctcaaatat atttttgtat
     6601 gcagtatata ataatcaaat tatacacttc ttataactgc attgatttga aaataatatt
     6661 aataattaat agaataaaaa atttaaatta aatttaaaaa aatttgttaa gtt
//
LOCUS       DAMJVG010000130         6350 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.135, whole genome shotgun sequence.
ACCESSION   DAMJVG010000130 DAMJVG010000000
VERSION     DAMJVG010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6350)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6350)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6350
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.135"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            285..1229
                     /locus_tag="PC512_003507"
     CDS             285..1229
                     /locus_tag="PC512_003507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase regulatory
                     subunit"
                     /protein_id="HDF2443203.1"
                     /translation="MKFLRIEDEVIYSKKRYKLKREIDKLFLDEEYFQIEPQLFEEYD
                     EFTTINNKIPEESMVKVVNGKVMVLRADITTSIIKSLVPRWEDGLKLKLFYNSSIYKN
                     KNTVGIKEIRQIGCEYLGEASVEADREVVKLALKILEKYNNNFILEVGSSKYIHGLLE
                     ELNLNKNCENQIKNLLYTKNTHELKVYIEELKIKREVKELLSNILSLQGNLYNVIEKS
                     NKFYCNNKMKQALEELKQVNNLIEECNFLDKARFDLSMITMLDYYEGIMFRGYYPNSY
                     KEILSGGRYDSLTKEYGKEIPAIGFTLSVDELMKYVYK"
     gene            1251..1877
                     /locus_tag="PC512_003508"
     CDS             1251..1877
                     /locus_tag="PC512_003508"
                     /EC_number="2.4.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase"
                     /protein_id="HDF2443204.1"
                     /translation="MDYLTIALAKGRIEGESFKKFKKMGLGDSIDTDTRKLIFKDEEN
                     KIIYIHVKPSDVVTYVEKGVADLGIAGKDTILENETDVYEIYDLGFGKCKFAVAGLKG
                     DSIYREDEYLKVATKYPNIAKKYFKEKGQKIEIIKLNGSVELAPIVGLSDVIVDIVET
                     GNTLKANGLEILEDICNISARIISNRASYRFKYEQIQNIIRLFEELDN"
     gene            1911..2960
                     /gene="hisC"
                     /locus_tag="PC512_003509"
     CDS             1911..2960
                     /gene="hisC"
                     /locus_tag="PC512_003509"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HDF2443205.1"
                     /translation="MREKESIRELKGYEPNHVNCKVKLDANEGSKRLFKYLIKEISDS
                     DIDLNLYPEDSYSDLKESIIDYINISGVNKKNLLVGNGSSEIIDLIIHTFVDKDEVIL
                     SFSPSFSMYSIYSQINGSKFIGVESDENLVINIDNVIEKVKENNPKIVIVCNPNNPTG
                     TILKREEIIKLLDSTNSLVVLDEAYMDFGEESMLSDVFKYDNLIVLRTLSKAFGLAGI
                     RTGYMLSNSSLINSVEKVRPPYNLNSLSDFIATRALRNKDVVKAYIKEVKEEREVLYK
                     EMIGMGIKAYKSQANFILFYSEIENLSQKLIDRGVLIRKFGGKLENYYRVTIGDKEEN
                     SMFVGAIRDILKKEK"
     gene            2963..3541
                     /gene="hisB"
                     /locus_tag="PC512_003510"
     CDS             2963..3541
                     /gene="hisB"
                     /locus_tag="PC512_003510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazoleglycerol-phosphate dehydratase HisB"
                     /protein_id="HDF2443206.1"
                     /translation="MRIWKVERNTLETQILVELNIDGSGKAEIDTGIGFLDHMLTLMS
                     FHGKFDLKVICKGDTYVDDHHSVEDIGIAIGEAFKNALGDKKGIRRYSNIYIPMDESL
                     SMVAIDISNRPYLVFNAKFDTQMIGSMSTQCFKEFFRAFVNESRVTLHINLLYGENDH
                     HKIESIFKAFARALKEGSEIVSNEIASSKGVL"
     gene            3543..4148
                     /gene="hisH"
                     /locus_tag="PC512_003511"
     CDS             3543..4148
                     /gene="hisH"
                     /locus_tag="PC512_003511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisH"
                     /protein_id="HDF2443207.1"
                     /translation="MNIIVDYGLGNIDSVSRGFRKAGIETKISSDIDEIKQADSLILP
                     GVGAFRDSISALDKLGLIPIIKEHVSKGKFMIGICLGMQLLYEKSYEYGEYEGLGLIK
                     GSIDKLDISLKVPHMGWNNLKFNKANDDILKYINEDDYVYFVHSYYANSSNEELIAFS
                     EYEKKIPAIVRKGNVYGIQFHPEKSGEVGLNILRAYGEMIK"
     gene            4145..4867
                     /gene="hisA"
                     /locus_tag="PC512_003512"
     CDS             4145..4867
                     /gene="hisA"
                     /locus_tag="PC512_003512"
                     /EC_number="5.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]imidazole-4-
                     carboxamide isomerase"
                     /protein_id="HDF2443208.1"
                     /translation="MIIFPAIDIKDNKCVRLTQGEFDKVNVYYDNPLEVAYKWKNEGA
                     EYIHIVDLNGARSEFGVNTKIIEDIANNIDIPIQVGGGVRDKEKVKSLINAGVTRVIL
                     GSIAIENLNLVEELVNEYKEKIVVSIDAKDGKVAVRGWEVVSNVDSLTLCKQLEKIGV
                     QTIVYTDISKDGMLQGPNFDIYERIAKETSLNVIASGGVTSIEDVKRLKAMNLYGAII
                     GKALYDKKIDFKEAQQLCLLGE"
     gene            4849..5607
                     /gene="hisF"
                     /locus_tag="PC512_003513"
     CDS             4849..5607
                     /gene="hisF"
                     /locus_tag="PC512_003513"
                     /EC_number="4.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="HDF2443209.1"
                     /translation="MLTRRIIPCLDVRNGRVVKGKKFKDIVDVDSPEVLGKFYSDCGA
                     DELVFYDITASNEERKTSLEFVTKVAENINIPFCVGGGVNKLEDFTDILRKGADKVSI
                     NSSAVKNPELIREASLKFGAQCVVLSIDAKKNEEGSWSVYVKGGREKTNLDAIEWAVK
                     GVELGAGEIVVNSMDEDGMKNGYDIELLSKITSLVNVPVIASGGAGKKEDFYEAVNKS
                     NVDGILAASVFHFGEIKINDLKKYLKDMGVEVRL"
     gene            5635..6303
                     /locus_tag="PC512_003514"
     CDS             5635..6303
                     /locus_tag="PC512_003514"
                     /EC_number="3.5.4.19"
                     /EC_number="3.6.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphoribosyl-AMP
                     cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE"
                     /protein_id="HDF2443210.1"
                     /translation="MDNKCNNVYSDEVEKFIRSIKFDDKGLVPVVVQEVVSKDVLMLA
                     YMNKDAIKKTLKDKVACYFSRSRQELWVKGETSGNTQKVVKMSYDCDVDTILLFVEQT
                     GVACHTGNYSCFYRDLFDDSSKMELEVQTNILKELYDLINERKNNPVEGSYTNYLFEK
                     GIDKILKKVGEESSEVIIASKNTDKSELIYEISDLVYHTLVLMIEKGVEIDEIKKELL
                     KRRK"
BASE COUNT         2597 a          540 c         1254 g         1959 t
ORIGIN      
        1 agaatattaa taaaaattat ttgggaggaa attatcatgg tgagattaaa tatagtaaaa
       61 ttaaatacaa aattaaatca tcaccatcat catagattaa agggattgta atatgaaatt
      121 aattcataga cacaagccct gtttttagtg taattggtct tgtatctatg atgggaagta
      181 attttaagag aaaattatag ccatataggt ataaagccta tgtggctttt ttattgtttt
      241 aaatttgcaa atataagagt aaatttaatg aagagggtga gaatgtgaaa tttttgagga
      301 ttgaagatga ggttatttat tctaaaaaaa gatataaatt aaaaagggaa atagataaac
      361 tttttttgga tgaagaatat tttcaaatag aaccacaatt atttgaagaa tatgatgaat
      421 ttacaactat aaataataaa attccagaag aatctatggt aaaggttgta aatggaaaag
      481 taatggtact tagagctgat ataactacaa gtataataaa aagccttgta ccaagatggg
      541 aagatggttt aaagcttaag cttttttata attcatcaat atataaaaat aaaaatacag
      601 ttggaataaa agagataaga caaataggtt gtgagtatct aggagaagcc tctgtagaag
      661 cagatagaga agtagtgaaa ttagctctta agatacttga aaaatacaat aataatttta
      721 ttctagaggt tgggagtagc aagtatattc atggtttgtt agaagaatta aatttaaata
      781 agaattgtga aaatcaaatt aaaaatttac tatatacgaa gaacactcat gaactaaaag
      841 tatatattga agaattaaaa attaagcgtg aagtaaaaga gttattatca aatattttaa
      901 gtttacaagg gaatttatat aatgttattg aaaaatcaaa caagttctat tgtaataata
      961 agatgaagca agctcttgaa gaattaaagc aagtaaataa cttgattgag gaatgtaatt
     1021 ttttagataa ggctagattt gatttatcaa tgattactat gcttgactat tatgaaggaa
     1081 ttatgtttag aggatactac ccaaactcat ataaagaaat tcttagtggt ggaagatatg
     1141 attctttaac taaagagtat ggaaaagaaa ttccagccat tggatttaca ctaagtgttg
     1201 atgagttaat gaagtatgta tataagtaaa gtttagaagg agggattgct ttggattatt
     1261 tgactatagc actagcaaaa ggacgaattg aaggggaatc atttaaaaaa tttaaaaaaa
     1321 tgggtctagg agacagtata gacacagata cgagaaaact aatttttaaa gatgaagaaa
     1381 ataaaattat atatatacat gtaaagccat cagatgtagt tacatatgtt gaaaaaggag
     1441 tcgctgacct cggtatagca ggtaaagata ctattttaga gaatgagaca gatgtatatg
     1501 aaatatatga tttaggtttt ggaaaatgta aatttgctgt agcaggatta aagggagata
     1561 gcatatatag agaagatgaa tatttaaaag tggcaacaaa gtatcccaat atagcaaaaa
     1621 agtattttaa agagaaaggt caaaaaattg aaataataaa attaaatggt tctgtagaac
     1681 tagctccaat agtagggttg tcagatgtaa ttgtagatat agttgagact ggcaatacac
     1741 ttaaagcaaa tggtcttgaa atattagaag acatatgtaa tataagtgct agaattatat
     1801 caaatagagc tagctataga tttaaatatg aacaaattca gaatataatt cgtttatttg
     1861 aagaacttga taattaaaat ataattgagc tttataagga gggatttaag ttgagagaaa
     1921 aagaaagcat aagagagtta aagggatatg aaccaaatca cgtaaactgt aaagtaaaac
     1981 ttgatgcaaa tgaaggaagt aagaggttgt ttaaatacct tattaaagaa atttcagata
     2041 gtgatataga tttaaattta tatcctgaag attcttatag tgatttgaaa gaatctataa
     2101 tagattacat aaatatttct ggagtaaata agaaaaatct tctagtagga aacggttcaa
     2161 gtgaaataat tgatttaata atacatactt ttgtagataa agatgaagta atattgagtt
     2221 tctctccaag ttttagtatg tattctatat atagtcagat aaatgggtct aaatttatag
     2281 gtgttgaaag tgatgaaaat ttagttataa atatagataa tgtgattgaa aaagtaaagg
     2341 agaataatcc taaaatagta attgtatgta atcctaataa tccaactgga acaatattaa
     2401 agagggaaga gataataaag cttttagatt caactaatag tctagtggtt ttagatgaag
     2461 catatatgga ttttggagaa gaaagcatgt taagtgatgt ttttaagtat gataatctaa
     2521 tagttcttag aactttatca aaggcatttg gattggctgg aataagaaca ggatatatgt
     2581 tatctaatag tagtttaata aattctgttg agaaagtaag acctccatat aatttaaatt
     2641 cattatcaga ctttattgct acaagagcac ttagaaataa agatgtggta aaggcttata
     2701 taaaggaagt aaaagaggaa agagaagttt tatataaaga aatgattggt atgggaatta
     2761 aagcatataa atcacaagca aattttatat tattttattc tgaaatcgaa aatttatcac
     2821 aaaaacttat tgatagaggt gttttaataa gaaaatttgg tggaaagtta gaaaattatt
     2881 acagagttac aattggtgat aaagaagaaa attctatgtt tgttggagct ataagagata
     2941 ttttgaaaaa ggagaaatag gtatgagaat ttggaaggta gaaagaaata ctcttgaaac
     3001 acagatttta gtagaattaa atattgatgg ttctggtaaa gctgaaatag atactggaat
     3061 aggattttta gaccatatgc ttaccttaat gtcatttcat ggcaagttcg atttaaaagt
     3121 gatttgtaag ggtgatacat atgtagatga ccaccatagt gtagaagata taggtatagc
     3181 tataggtgaa gcatttaaaa atgctctagg tgacaaaaaa ggaatacgaa gatattctaa
     3241 tatctatata cctatggatg aatctctatc aatggtagca atagatataa gcaatagacc
     3301 ttatcttgta tttaatgcta aatttgatac ccaaatgatt ggtagtatga gtactcaatg
     3361 ctttaaagaa ttttttagag cttttgtaaa tgaatcgaga gtaacattac atatcaatct
     3421 cttatatggg gaaaatgacc atcataagat agaaagtatt tttaaagcat ttgcaagagc
     3481 tttaaaagag ggtagtgaaa tagtttctaa tgagatagca tcttcaaagg gggttttgta
     3541 gaatgaatat aatagtagac tatggtcttg gaaatataga ttctgtgtct aggggtttta
     3601 gaaaagctgg aatagaaact aaaatttcta gtgatataga tgaaataaaa caggcagatt
     3661 cacttatact tccaggtgtt ggagctttta gagattctat aagtgcctta gataaactag
     3721 gattgatacc aataataaag gagcatgttt ctaagggtaa atttatgata ggtatatgtc
     3781 taggaatgca attactttat gaaaaaagtt atgagtatgg agaatatgaa ggattaggac
     3841 ttataaaagg aagtattgat aaactggata taagtttaaa agtgccacat atgggatgga
     3901 ataatctaaa atttaataag gcaaatgatg atatacttaa atatataaat gaagatgatt
     3961 atgtatactt cgttcactca tattatgcaa attcatcaaa tgaagaacta attgcatttt
     4021 cagaatatga aaagaaaatc cctgctattg ttagaaaagg caatgtatat ggtatacaat
     4081 ttcatcctga aaaaagtgga gaagtagggt taaatatatt aagagcatat ggggagatga
     4141 taaaatgata atatttccag caatagatat aaaagataat aagtgtgtaa gacttacaca
     4201 aggagaattt gacaaagtaa atgtatatta tgataatcca ttagaagtag catataaatg
     4261 gaaaaatgaa ggagcagaat atatacatat agtagattta aatggtgcta gaagtgaatt
     4321 tggtgtaaat acaaaaataa ttgaggacat agcaaacaat atagatatac ctattcaagt
     4381 tggcggtgga gttagggata aggaaaaagt caaaagttta ataaatgctg gtgttactag
     4441 agtaatatta ggtagtatag cgattgaaaa tttgaattta gttgaagaat tggtcaatga
     4501 atataaagag aaaattgtag tttctataga tgctaaagat ggaaaagtag cagttagggg
     4561 atgggaagtt gtaagcaatg tagactcatt aacattatgc aaacaacttg aaaagatagg
     4621 tgtacaaact attgtttata cagatatatc aaaagatggg atgttgcaag gtccaaattt
     4681 tgacatatat gaaagaatag caaaggaaac atcactaaat gttattgctt ctggaggcgt
     4741 aacttctata gaagacgtaa aaagactaaa agctatgaac ttatatggtg caataatagg
     4801 taaagcgctt tatgataaaa agatagactt taaggaggca caacaattat gcttactagg
     4861 agaataatac cttgtctaga tgtgagaaat ggaagagtcg taaagggaaa aaaatttaaa
     4921 gatatagtag atgttgatag tccagaagta cttggaaaat tttatagtga ttgtggtgca
     4981 gatgaacttg tattctatga tataactgca tcaaatgaag agagaaagac atctttagaa
     5041 tttgtgacaa aagttgcaga aaatataaat ataccatttt gtgttggtgg aggagtaaat
     5101 aaattagaag atttcactga tattttaaga aaaggtgctg ataaagtttc tataaattca
     5161 tcagcagtca aaaatcctga attaataagg gaagcttcat taaaatttgg agcacaatgt
     5221 gttgttttat cgatagatgc aaagaaaaat gaagagggtt catggagcgt atacgtaaaa
     5281 ggtggaagag aaaaaactaa tctggatgca attgaatggg ctgttaaagg tgtagaactt
     5341 ggagcaggag aaatcgttgt aaatagtatg gatgaagatg gaatgaaaaa tggatatgat
     5401 atagaattat tatcaaagat aacttcttta gtaaatgtac ctgtcatagc atctggaggc
     5461 gctggaaaaa aggaagattt ttatgaggcg gttaataaat ccaatgtaga tggaatttta
     5521 gcagcatctg tttttcattt tggcgagata aaaataaacg atttaaagaa atatttaaaa
     5581 gacatgggtg tagaagtaag attataagtt aaatactaaa aggagattag aaatatggat
     5641 aataagtgta acaatgtata cagtgatgaa gtagagaaat ttataagaag tataaagttt
     5701 gatgataaag ggttagtccc tgttgttgtt caagaggtag ttagcaaaga tgtactgatg
     5761 ttagcatata tgaataaaga tgctataaag aaaaccttaa aagataaagt agcttgctat
     5821 tttagtagaa gtagacaaga actttgggtt aaaggtgaga catctggtaa tactcaaaaa
     5881 gtagttaaga tgtcttatga ttgtgatgta gatactatac tactttttgt tgaacaaact
     5941 ggtgtagctt gtcatacagg caattattct tgtttttaca gagacttgtt tgatgatagt
     6001 tcaaaaatgg agcttgaagt acaaacaaat atattgaaag aattatatga tttaatcaat
     6061 gaaagaaaaa ataatccagt tgaaggttct tatactaatt atctttttga aaaaggaata
     6121 gataagattc ttaaaaaagt aggtgaagag agtagtgagg taattatagc atcaaaaaat
     6181 accgataaaa gtgaacttat ttacgaaatt agcgatttag tatatcatac attggtttta
     6241 atgatagaaa aaggtgttga aattgatgaa ataaaaaaag aattacttaa aagaagaaaa
     6301 tagaataaga tagattaatg ggtaataaga aaatatacca cttttaataa
//
LOCUS       DAMJVG010000131         6039 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.136, whole genome shotgun sequence.
ACCESSION   DAMJVG010000131 DAMJVG010000000
VERSION     DAMJVG010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6039)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6039)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6039
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.136"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(5..412)
                     /locus_tag="PC512_003515"
     CDS             complement(5..412)
                     /locus_tag="PC512_003515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443211.1"
                     /translation="MSKVAKATFYLMIVTIISKILGMGRELVLSSIYGTGLYTESYLT
                     AMNIPNIIFAAIGTAIVTTFIPMYQDISSKQGEKQALKFLNNVLNIIVGICIVVAILG
                     VIFSKQLVSIFAIGFEGERFLLTVKFTKILIKK"
     gene            complement(886..1770)
                     /locus_tag="PC512_003516"
     CDS             complement(886..1770)
                     /locus_tag="PC512_003516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF2443212.1"
                     /translation="MDTKKENNYENYICVGSSNVSNAMKMYLKEIEEYKMLSAGEEVE
                     LAKEIINSSSVAKEKFINSNYRLVVSIAKRYKRDSIDMLDLIQAGNIGLIKAVEKYDY
                     KKGYKFSTYATWWIKQSITRYIDDCENTIRIPIHLHQRINFVKKKKQELLNVLLREPT
                     IDEIADACGLEVDKVLELLRRDKNVVSLDTPLKEDEDSSLVEFIPSDADFKDVVIHEV
                     EQHNLKEKIEELLTGLGEQEQQVLRMRFGIDDDDPKTLEQIGKVFGVTRERIRQIEAK
                     AIRKLRHPSKLKQLKHFY"
     gene            complement(2061..2537)
                     /locus_tag="PC512_003517"
     CDS             complement(2061..2537)
                     /locus_tag="PC512_003517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction enzyme HsdR N-terminal
                     domain-containing protein"
                     /protein_id="HDF2443213.1"
                     /translation="MSKELVKDRVIKYLIEDLLVPQDMIDTNVELAEFEEGAEGILDI
                     VVNVKDEEDYYAPVMIVQCLDEDVELEGEVLQKQIEFLEEVDNITMSGRLVLTNGDAM
                     MYADWRGEEYDTEAALPTYDIMVKEFHEMEQQVKDLEEHHHHDENCGCGCNHHHEN"
     gene            2803..3978
                     /locus_tag="PC512_003518"
     CDS             2803..3978
                     /locus_tag="PC512_003518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HDF2443214.1"
                     /translation="MKFKKQISSIVVSTMLVLGSMNLSYADGTNVVTLGANLSESQKQ
                     QMLNYFGVKKDQVLVLDVTNAEERQYLQGVATEGQLGKVTISCSYVEPTKKGNGINVK
                     TANLTWVTSSMIASTLTTAGLEDANVIAAAPYPVSGTGALTGIMKAFEDASGKKLDET
                     KKEIASEELVVTGDLGDDIGQEKATGVMNDIKTEIVKNGTKDTNQIANTINNVVNNYN
                     ITITPEQKEQIKGVMKKIADQNYDYNSMKNTLDNVSDNVNEQLKKLGESVKGSGILDT
                     IGGWFSGIGDWFSGLFSGGDKKDLGILNNTNDESLGSDAVINSTEGVQINPQNNTNSN
                     NDSDTNSSKNDTSSNNENNDSSQTNENNTTNNSENQSNNNDSVGFFEKIKNWLSGLF"
     gene            complement(4059..4862)
                     /gene="proC"
                     /locus_tag="PC512_003519"
     CDS             complement(4059..4862)
                     /gene="proC"
                     /locus_tag="PC512_003519"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HDF2443215.1"
                     /translation="MKKIGFIGAGNMASAMIGGIVNSKLVEPNMVIASAYSQGTLDRI
                     DANFGINTTKDSKEVTRTSDIVIVAVKPDIYDDILEEIKDFIDDNKIIVTIAAGKSIK
                     DIESIIGEDKKIVRTMPNTPALVNEAMSSLSINKNINKEDLEAVTEVFNSFGNTEVVP
                     EYLIEAVIGASGSAPAYVFLFIEAIADAAVIAGMPRPQAYKFASQAVMGSAKMVLETG
                     KHPGELKDMVCSPGGTTIEAVKVLEEEGFRASVIKAICACIEKSKKMSE"
     gene            complement(4902..5486)
                     /locus_tag="PC512_003520"
     CDS             complement(4902..5486)
                     /locus_tag="PC512_003520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2443216.1"
                     /translation="MNKDIGAKIKQLRTQKQMTLKDMSEKTNLSIGFLSQLERGLTSV
                     ATDSLGKIASVLDVELTYFFMKPKEHKRAVLRSYEKEVFDVENSTFIHYHLSSSLKEK
                     TMLPRLIEILPSKSSEEICCYVHEGEEFVYVLEGTLTVFLGDEQIEMYPGDTIHYNSE
                     KNNHNWVNYTNKVVKILVVSIPNPFEKSDAVKEA"
BASE COUNT         2022 a         1011 c          664 g         2342 t
ORIGIN      
        1 gtagctattt tttaatcaat attttagtaa attttacggt aagtaaaaac ctctctcctt
       61 caaatcctat agcaaatata cttacaagtt gctttgagaa aataactcct aatatagcta
      121 caactatgca tataccaact attatattta aaacattgtt taaaaacttt agtgcttgct
      181 tttcaccttg tttactactt atatcttgat acattggaat aaaagtagta actatagcag
      241 tacctattgc tgcaaatata atatttggta tattcatagc tgttaaataa ctctctgtat
      301 ataagcctgt accataaatt gatgataata ctaattctct acccattcca agaatcttag
      361 agattatagt aactatcatc aaataaaaag ttgctttagc taccttgctc attttatcac
      421 tccacttcta acatacctct ttttaatcaa gtaaaattta gctcattaga tataattcta
      481 tcaactaatt tgccttgctt agccctatca aaatataatt aacacctatt tcttaatata
      541 tcacaaacta cattattctt catatttttt tatttctcca ataagtttta catttttcct
      601 atataaattg tatagcttca attatattca aagaaatgga gttgctaccc gataacttta
      661 aaagtaaaaa acagatttta ttatcttttt aaactatatt ctaacatatt ttgtccatat
      721 tgagaaattt tactaaacta ttatgtactt tattaaataa ataaaataac agcacaccta
      781 taaaatacaa gtgtgctgtt cataaacaga ttttataaaa aaataattcc taagtagaga
      841 ttaacatgct ttctcatact ctcatatata atgtgtctaa aaatattaat aaaaatgttt
      901 taattgtttt aacttacttg gatgtcttaa ttttcttatt gctttagctt ctatctgtct
      961 tattcgttct ctggtaactc caaatacctt tccaatctgt tctagtgttt tagggtcatc
     1021 atcatcaatt ccaaatctca ttcttaaaac ttgctgttct tgctctccaa gacctgtaag
     1081 tagttcttct atcttttctt ttaaattatg ctgttcaact tcgtgtatta caacatcttt
     1141 aaaatcagca tctgatggta taaattcaac taaactacta tcctcatctt cttttaatgg
     1201 agtatccaaa gatacaacat ttttatctct tcttaataat tccaacactt tgtcaacttc
     1261 taagccacat gcatctgcaa tctcatctat agttggctct cttaataata catttaaaag
     1321 ttcttgtttc tttttcttta caaaatttat tctctgatga agatgtatag gtatcctaat
     1381 agtattttcg caatcgtcga tatatcttgt tatactttgt tttatccacc aagttgcata
     1441 agtgctaaat ttgtatcctt ttttataatc gtacttttct acagctttta taagtcctat
     1501 atttcctgct tgaattaaat ccaacatatc aatactatct cttttatatc tctttgctat
     1561 gctcactacc aacctataat ttgaatttat aaatttttct tttgctactg aagatgagtt
     1621 gattatttcc ttagccagct ctacctcttc tcctgctgac aacattttgt attcctctat
     1681 ttcctttaaa tacattttca tcgcattcga tacatttgat gaacccacac aaatataatt
     1741 ttcataatta ttttcttttt tagtatccat aatcaaaccc cttctattca tagaatttgc
     1801 taaaacaaaa ataaataatt taaacctaca taatctacaa ttacataata tcccattctt
     1861 taaatgaatt gttttgtata ttatgtatac aaatttataa aaactatacc tataatatta
     1921 ttctacttct aacagcaata tcctccttat atatataatt tattttatta tatgttgtta
     1981 tattcttagt tttttgaatg atatatgtct aaaaaaagac tgtttactaa acagtctttt
     2041 tttatatata tgctcaatat ttaattttca tgatgatgat tacatccaca tccacaattt
     2101 tcatcatggt gatgatgttc ttctaaatct tttacctgtt gttccatttc atgaaactct
     2161 tttaccatta tatcataagt tggaagagct gcctcagtat cgtattcttc ccctctccaa
     2221 tcagcgtaca tcatagcatc tccattagtt aaaaccaatc tacctgacat agttatatta
     2281 tccacttctt ctaaaaattc tatttgtttt tgtaaaactt ctccttctaa ctccacatct
     2341 tcatctaaac attgcactat cattacaggt gcataataat cttcttcatc tttaacattt
     2401 acaacaatat ctaaaattcc ttctgcacct tcttcaaatt ctgccaactc aacatttgta
     2461 tcaatcatat cttgaggtac taataaatct tctattaaat attttattac tctatctttt
     2521 actaattctt ttgacattta tttttctcct tccgattcta taacattatc ataatcattt
     2581 ctatattata gtatactaca ttaattgttt tttcaatctc ttacaaaaat tattttttat
     2641 tatcttcctt atattccctt ttttattaca aagttgtaat cgcattgatt taaaaaatag
     2701 tttatattta gtataataga aatgtagcac atatttttat tcaatatatt aataaaaaaa
     2761 tatattgaaa atgtaatgta tgttaaatct aggaggaata ttatgaagtt taaaaaacaa
     2821 attagttcta ttgttgtgtc tactatgctt gtacttggga gtatgaacct ttcttatgca
     2881 gacggtacaa atgtagttac acttggagct aacttatcag agtctcaaaa gcagcaaatg
     2941 cttaattact ttggagtaaa aaaagaccaa gtcttagttt tagatgtaac aaatgcagaa
     3001 gaaagacagt atttacaagg tgttgcaaca gagggtcaac ttggaaaagt tactatctct
     3061 tgctcatacg ttgaacctac taaaaaagga aatggaatta atgttaaaac agcaaactta
     3121 acttgggtaa ctagttcaat gattgcttca acccttacaa cagctggtct tgaagatgca
     3181 aatgttattg ctgctgctcc atatcctgta agtggtactg gagcattgac aggaatcatg
     3241 aaagcatttg aggatgcttc aggaaagaaa cttgatgaaa ctaagaaaga aattgcttct
     3301 gaagaattgg tagttacagg tgacttagga gatgatatag ggcaagaaaa agcaacaggt
     3361 gtaatgaatg atataaaaac agaaattgta aaaaatggta caaaagatac caatcaaata
     3421 gcaaatacaa taaataatgt tgtaaataat tacaatatta ctattacacc agaacaaaaa
     3481 gaacaaatta aaggtgtaat gaaaaaaata gctgaccaaa attacgatta caatagcatg
     3541 aaaaatacac tagataatgt atcagataat gtaaatgaac aattaaagaa attaggtgaa
     3601 agtgttaagg gttctggtat actagatact attggtggat ggtttagtgg aataggagac
     3661 tggttctctg gtttattctc aggcggagat aaaaaagatt tgggaatctt aaataatact
     3721 aatgatgagt ctcttggctc tgatgctgta ataaattcta cagaaggtgt tcaaataaat
     3781 ccacaaaata atactaattc taacaatgat agtgatacaa atagctcaaa aaatgatact
     3841 tcaagtaata atgaaaataa cgatagttct caaacaaatg aaaacaacac aacaaataat
     3901 tcagaaaatc aatcaaataa taatgactca gttggtttct ttgaaaaaat aaaaaattgg
     3961 ctttcaggct tattttagaa attaaacaaa taaaaagaat tgcctaaaat ggaaattttc
     4021 tataaaaggc aattctcttt atttacaata aatttttatt actcactcat ttttttagat
     4081 ttttctatac atgcacatat tgcttttatc acagaagctc taaaaccttc ttcttcaagt
     4141 actttaactg cttctatagt agttccacca ggtgaacata ccatatcttt taattcacca
     4201 ggatgttttc ctgtctcaag taccattttt gcagaaccca taacagcctg tgatgcaaac
     4261 ttatatgctt gtggtcttgg cattcctgca attactgctg catctgctat agcttctata
     4321 aataaaaata catatgctgg tgcagaacca cttgcaccaa ttacagcttc tataagatac
     4381 tctggtacta cctcagtatt tccaaaagaa ttaaatactt ctgtaactgc ttctaagtct
     4441 tctttgttta tatttttatt tatagaaaga gaagacatgg cttcatttac aagagctgga
     4501 gtatttggca tagttctaac tattttttta tcttctccta taatagactc tatatctttt
     4561 atagattttc ctgctgctat tgtaactata attttattgt catctataaa gtcttttatc
     4621 tcttccaaaa tatcatcata tatatctggt ttaacagcta caattactat atcagaggtt
     4681 ctagttactt ccttcgagtc ttttgtagta tttattccaa aatttgcatc tattctatca
     4741 agagttcctt gactatatgc tgatgctata accatattag gttcaactaa ttttgaattt
     4801 actattcccc ctatcatagc gcttgccata tttcctgcac ctatgaatcc aatttttttc
     4861 actttagtac ctccttattg actaatagta atcgttaaaa tttaagcttc tttaactgca
     4921 tcagactttt caaatggatt tggtatactt actaccaaaa ttttcactac cttattagta
     4981 tagttgaccc aattatgatt gttcttttca ctattatagt gtattgtgtc tcctggatac
     5041 atttctattt gttcatctcc caaaaacact gtaagagtac cctctaatac atacacaaat
     5101 tcctcacctt catgtacgta acaacaaatt tcctcactac tcttacttgg aagaatttca
     5161 attaatcttg gtagcattgt tttttccttt aaactagatg ataaatgata atgtataaat
     5221 gttgagtttt ctacatcaaa tacttctttt tcataacttc ttaatacagc tcttttatgc
     5281 tcttttggct tcataaaaaa gtaagttaat tctacatcta gtacacttgc tatttttcct
     5341 aaggaatctg ttgccacact tgttaatcct ctttcaagtt gtgataaaaa accaattgac
     5401 aagtttgttt tttcactcat atccttcagc gtcatttgct tttgagttct gagttgcttt
     5461 atttttgctc ctatgtcctt attcaaaacc atcaccccta aataatttta attttttcat
     5521 aatataaata caaaaatata aatataggta ctgaacctat ctttatttca tttaaaaaaa
     5581 tttttataag tattactata atttatcaat ctttttttgt ctacattttt acgattattt
     5641 acgatttatt tttcacatat gtatatttaa tcttgccaac taaagataca ttttttataa
     5701 gcatttactc tttatataat aaaacttaag ttgttcatga gtcttcttct ggtttaatta
     5761 ttaaaatttc aaattatatt attatttcta cacattatta catcctttag tacaattata
     5821 acataatttt acaatttaat gatatctatt caatgtcttt ttttactcta caacatattt
     5881 tattttagag tttaatacta tatatatttt ttatatacag ccttgtcatt ttttagattg
     5941 tcaagagtta ttgaagtatt ttatgtagat ttagatttta ttttctaatt tctcatttaa
     6001 caagaattgc ttatgataaa aaataatatc atctcaata
//
LOCUS       DAMJVG010000132         5981 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.137, whole genome shotgun sequence.
ACCESSION   DAMJVG010000132 DAMJVG010000000
VERSION     DAMJVG010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5981)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5981)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5981
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.137"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            163..975
                     /gene="modA"
                     /locus_tag="PC512_003521"
     CDS             163..975
                     /gene="modA"
                     /locus_tag="PC512_003521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF2443217.1"
                     /translation="MFKKLSVLALAMIISLSITACNSKENKANDESNTKVTTADDSKE
                     KETLFVYSGAGLKKPMDEIAKKFEKENNVKVEYSYAGSAQLIAQIETSHKGDVFIVGS
                     EPIYSKAFEKELVGEHKTVAHHTPAIVVPKGNPANIQKLEDLNKDGVKLILGDKESNA
                     IGKTTQKILEKNNLKSINDNVVSTAATVNEMIVQLTSSKADATIATKDSVFGNEDVEV
                     IEIAQDKNIDQLISAGIVNYSDKKDLANKFINYIESDEAKQIFKKYGFEPVK"
     gene            985..1776
                     /locus_tag="PC512_003522"
     CDS             985..1776
                     /locus_tag="PC512_003522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2443218.1"
                     /translation="MKNKFFTTLLTGFFAIVFLFIVSPLLMLIIKGISYVPICLKSVE
                     VQYAITLSIKTSLISTIVCLLLAIPVAYFLHITKLPFKKLIIQIINLPMSLPHLVSGI
                     ALLLLFGRMGIGDSIYKIFKLDFIFTKQGIVLAQIFVNLPLTIKILHTSLNESNEKMI
                     FVARTLGCNSWEAFRFIILPNLKTGIISATVMTWSRALGEFGAVAMIAGSTRMKTEII
                     PTSIYLNMSTGDIDIAIGIAVILIFLSLTCLMLFEIFFNREVDKN"
     gene            1778..2473
                     /locus_tag="PC512_003523"
     CDS             1778..2473
                     /locus_tag="PC512_003523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2443219.1"
                     /translation="MLKIKNLSLDLPNFKLQENSLNINNHEYFVLLGASGSGKTLFLE
                     TLAGRYPSAKGNVSYKENLISNLPPENRNIGFVYQNFELFPNMNVEDNIRFPLKLRKI
                     PIDEQILKANHLSKLMQIEDIKNRYPKNLSGGEKQRVAFARALIAEPDILLLDEPMSS
                     LDYITKKHISKILKDVYIKYKPTVIHVTHDISEAMFFAHKIGIMNNGKINHIFDLNEE
                     IKNKGESFFYEYI"
     gene            2460..3191
                     /locus_tag="PC512_003524"
     CDS             2460..3191
                     /locus_tag="PC512_003524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443220.1"
                     /translation="MNIFDILRDYLLVQVDKYNLNMDMISIVSKSLSSKEAIGNTKRK
                     DFPIIVGKEIMLEADFKGAKGQAFTSTPSTFEGSLKDILSLDLHDNSHDRSLFIASLN
                     AVMKYLGKTDRTIHCKNNEPEVCAKKFPEFIKMEFGNPKVAIIGYQPAIIDNIKDFFE
                     TRVLDLNPEFVDTIQYNVKIEDGIRDYEDVISWADLVICTGSTLCNNSIINFLSLNKP
                     VYYYGTTIAGASNILGLKRLCFCSK"
     gene            3505..4305
                     /locus_tag="PC512_003525"
     CDS             3505..4305
                     /locus_tag="PC512_003525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HDF2443221.1"
                     /translation="MTFKNKKFTINKYKILSIILVLCLILTAFSSYVNYSHKKFKDYV
                     VFYVQHQDDEVLWAGSAIVNAIKERGKNHVFVVLVSTGCGISVFDKYKKYENLTNIQK
                     SEYRNREFLASLNSLGVIRENIILLPETNTNGNTDFNYMEKIALTFEEKFKNVTHIAH
                     TYKLDDHLQHLKNGSVIQNLYNAGKIKDAKYFVKPKFADKITFNNKIVYKAHSTEDYE
                     KVKNACQQYKIVDELEYREGIGYKSDHKSFDKLLNNKDVPAILHTPNL"
     gene            4844..5560
                     /locus_tag="PC512_003526"
     CDS             4844..5560
                     /locus_tag="PC512_003526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2443222.1"
                     /translation="MNQNILVVDDDREIVDAIEFYLRPDNFNVLKAYDGLEALDILIE
                     NDIKLIIMDVMMPNLDGLKTTLKIREKRNIPIILLSAKSEDMDKIIGLNMGADDYITK
                     PFNPLELTARVKSQLRRYINLGDFSNTNNSNDTNYILKSGGLELNTDTKIVSLDGEEI
                     KMTPLEYKILTLLMSRKGKIFSSHEIYENVWNEDAYSCERTIAVHIRRIREKIEINPK
                     EPKYLKVVWGIGYKIEKLNY"
BASE COUNT         2328 a          728 c          844 g         2081 t
ORIGIN      
        1 aataactacc tatggaaatg acattatgaa tagatttttt cttaactata cataacaaaa
       61 cataacaaaa cattataaaa cataacaaaa acttagacat cgttttctta gtatgatata
      121 ctaaaaaaga atttacacta atttaataag ggggaatatc ttatgtttaa aaaactttca
      181 gtactagctt tagctatgat tatttcatta agtattactg catgtaattc taaagaaaac
      241 aaagctaatg atgaatctaa tactaaagtg acaacagctg atgattcaaa agaaaaagag
      301 actctttttg tctattcagg ggcaggttta aagaaaccaa tggatgaaat agcaaaaaaa
      361 tttgagaaag aaaataatgt caaagttgaa tatagctatg caggttctgc acagctaata
      421 gctcaaattg agacaagtca caaaggagac gtatttattg ttggttctga accaatttat
      481 tcaaaggcct ttgaaaaaga acttgtaggt gaacataaaa cggttgcaca tcatacacct
      541 gcaatagttg tacctaaagg aaatccagct aatattcaaa aattggaaga cttaaataaa
      601 gatggagtta aacttatttt gggagacaaa gagtctaatg ctataggtaa gactacacaa
      661 aaaatacttg aaaaaaataa tttaaaatct ataaatgata atgttgtctc tacagctgca
      721 actgtaaatg aaatgattgt acagttaaca tcaagtaaag ctgatgctac aatagccaca
      781 aaagattcgg tctttggtaa tgaagatgta gaagttatag aaattgccca agataaaaat
      841 atagaccaac tcatatcagc aggaatcgta aactatagtg ataaaaaaga tttagctaat
      901 aaatttataa attatataga gtcagacgaa gctaaacaga tatttaaaaa atatggtttt
      961 gaacctgtta agtagtgatt aaacttgaaa aataaatttt ttactactct acttactgga
     1021 ttttttgcta tagtcttttt gtttattgta tcaccacttc ttatgttaat cattaaaggg
     1081 ataagttatg ttcctatatg cttaaaatca gtggaagtac agtatgcaat aacacttagt
     1141 attaaaacat ctttaatatc tactatagta tgccttttat tagctattcc agtagcatat
     1201 tttttacata ttactaaatt accatttaaa aaactgatta tacagataat aaatctccct
     1261 atgtctcttc cacacttagt atcaggaatt gctcttttac ttttgtttgg aagaatgggg
     1321 attggagatt ccatttataa gatttttaag cttgatttta tatttacaaa gcaaggtata
     1381 gttttagcac aaatatttgt aaatcttcca cttactatta aaatacttca cacttcatta
     1441 aatgaaagta atgaaaagat gatatttgtt gcacgtaccc ttggatgtaa tagttgggaa
     1501 gcatttagat ttataattct tccaaatcta aaaactggaa tcatatctgc aactgtaatg
     1561 acttggtcaa gagcacttgg tgaatttggt gcagtagcta tgatagcagg ttctacacgt
     1621 atgaaaactg aaattattcc tacatctata tatttaaata tgtctactgg tgatatagac
     1681 attgctatcg gaatagctgt aattttgata tttctctcac ttacatgctt gatgcttttt
     1741 gagatatttt ttaatagaga ggttgataag aattaatatg ttaaaaataa aaaatttatc
     1801 tcttgattta cctaatttta aattacaaga aaatagttta aatattaata atcatgaata
     1861 ctttgtttta ttaggagcta gtgggtcagg taaaactcta tttctagaaa cattagcagg
     1921 aagatatcca tctgctaaag gaaatgtatc atacaaagaa aatttaatat caaacttacc
     1981 tccagaaaat agaaatatag gatttgtata tcaaaatttt gaattatttc caaatatgaa
     2041 tgttgaagat aatataaggt ttccacttaa attgagaaaa atacctatag atgaacagat
     2101 tcttaaggct aaccacttgt ctaaattaat gcagatagaa gatataaaaa ataggtatcc
     2161 taaaaattta agtggaggcg aaaagcaacg agttgctttt gcacgtgcct taatagctga
     2221 acctgatata ttacttttag atgaacctat gagttcattg gattatatta caaaaaaaca
     2281 tataagcaaa attttgaagg atgtctacat aaaatacaaa ccaacagtga ttcatgttac
     2341 tcatgatatt tctgaagcaa tgttttttgc tcataagata ggaataatga acaatggaaa
     2401 aataaatcat atttttgatt taaatgaaga aataaaaaat aaaggagaat cttttttcta
     2461 tgaatatatt tgatattttg agagattatc tattagtaca agtcgataaa tataatttaa
     2521 atatggatat gataagtatt gtgtccaaat ctctatcttc aaaagaagca attggaaata
     2581 ctaagcgtaa agatttccca attatagttg gtaaagaaat aatgcttgaa gctgacttta
     2641 aaggagctaa aggacaagca tttacttcta ctccatctac atttgaaggt tctttaaaag
     2701 acatattatc attagattta catgacaatt ctcatgatag aagtcttttt atagcatcat
     2761 taaatgcagt tatgaaatac ttaggcaaga cggatagaac cattcattgt aaaaataacg
     2821 agccagaggt atgtgcaaaa aaattccctg agtttataaa aatggaattt ggtaatccaa
     2881 aagtagcaat tataggatat caaccagcca taattgataa tattaaggac tttttcgaaa
     2941 caagagtatt agatttaaat cctgaatttg tggatactat tcaatataat gttaagattg
     3001 aagatggtat acgagattat gaagatgtaa tatcttgggc tgatttagtg atttgcacag
     3061 gaagtacatt atgtaataac tcaattataa attttctatc acttaacaaa ccagtttact
     3121 attatggaac tacgatagct ggtgcatcaa atattttagg tttaaaaaga ctctgttttt
     3181 gtagtaaata agcaatcata tcatcaagga gtacacaaat atatatgtgt actctttaaa
     3241 tttaaaaagt tattactttt attctaagta ctaaagtaaa attctattaa aatgaatccc
     3301 gaataaatgt acaatccctt taaatctcaa ttcctatcaa tcattaatat tttgattagt
     3361 cttatacata aatgttttct ttattttaaa ctaataaaaa aattttattc cattaatcta
     3421 ctctatattt ttcagcattt aagaaataat ttttagtact ttgtttgata atataactaa
     3481 gacaaccttt caggagatga ttaaatgaca tttaagaata aaaaatttac tataaataaa
     3541 tataaaattc tatctattat tctagtttta tgtttgattt taaccgcttt tagtagctat
     3601 gtgaattata gtcataaaaa atttaaagat tatgttgtct tctatgttca gcatcaagat
     3661 gatgaagtgt tgtgggctgg gagtgctatt gttaatgcta taaaagaaag aggaaaaaat
     3721 catgtatttg tggttttagt atctactgga tgtggtatat ccgtctttga taaatataaa
     3781 aaatatgaaa acctaacaaa tatacaaaaa tcagaatata gaaatagaga atttttagct
     3841 tctcttaata gccttggtgt aataagggaa aatataatat tattaccaga aacaaataca
     3901 aatggtaata ctgacttcaa ttacatggaa aaaattgctc ttacatttga agaaaaattt
     3961 aaaaatgtaa ctcatatagc acatacttat aaattagatg accatttaca acatttaaaa
     4021 aatggttctg ttatccaaaa tttatataat gctggtaaaa taaaagatgc taaatatttt
     4081 gtaaaaccta aatttgctga taaaataact tttaataata agatagttta taaagctcat
     4141 tctactgagg actatgaaaa ggttaaaaat gcctgtcaac aatacaaaat tgttgatgaa
     4201 ttagaatata gagaaggtat tggctataag tctgaccata aatcatttga taagttatta
     4261 aataataaag atgttcctgc tatacttcat acacctaatt tataagaaat atttattctt
     4321 taatttaagt tataaaaagg aaattatttg agattttgtg atatagcact ttttgtgcta
     4381 tactactttt tctcatacaa ctattaccca tatctaattt catcatctct taaaatatat
     4441 aaagatatca tcattaaaac ctataagcct tattaaatgc tttatacata cctacattaa
     4501 actacctgtt tatattaaac tacattaaaa taaatatttg ttataaattc ttaataatta
     4561 tgaaactcat ttgttattta tatttgttaa tatatgttta aacctaaaaa attaataaac
     4621 caaaataaca taagaagtgt gatagattac cctagatatt ttcataaact tttaccttca
     4681 gattaatatg ggcgtctata cttttaaatt tactatatgc attgacaata tattaaaagt
     4741 actagttttt atttcataat gaacgggctt actgttttct aatacctctt tttggtataa
     4801 aataaaaatt ggttaaaaat aaaatttcaa gggggttaat aaattgaatc aaaatatatt
     4861 ggttgtagat gatgatagag agatagttga tgctatagag ttctatttga gacctgataa
     4921 ctttaatgtt ttaaaggcat atgatggact tgaagcattg gacatactaa tcgaaaatga
     4981 tattaaatta ataataatgg atgtaatgat gcccaattta gatgggctta aaactacact
     5041 taaaataaga gaaaaaagga atataccaat aattctctta tctgcaaaat cagaagatat
     5101 ggacaaaatt ataggtctta atatgggtgc tgatgactat ataactaaac catttaatcc
     5161 actagaactt actgctcgag taaaatctca acttagaagg tatataaatt taggtgattt
     5221 tagtaataca aataactcaa atgatactaa ttatattcta aaaagtggtg gcctagagct
     5281 aaatacagat acaaaaatag tttctttaga tggtgaggaa attaaaatga caccacttga
     5341 atataaaata cttacacttc ttatgtcacg aaaaggtaaa attttctctt ctcatgagat
     5401 ttatgaaaat gtctggaatg aggatgctta tagttgtgag agaactattg ctgttcatat
     5461 tagaagaatt agagaaaaga ttgaaattaa tccaaaagaa ccaaaatatt taaaggtggt
     5521 gtggggcatt ggttacaaaa ttgaaaaact taattattaa tgattctaaa gcaaaattta
     5581 ttttattatt attactgttt ctattagttt ctatattatt tgaagcagtt tatgatttga
     5641 ataataactt ttctaatatt aattattatt atagagagtt tgctctccct tatttttatt
     5701 ttttcggtac tcctgtacat ttgtcaaaag tagaattaga gtttgtctgc ataggtatta
     5761 tattatcaag ttttttattg actatactat gttttacatt gtataaaaaa aataaacaaa
     5821 ctaaagtcaa attcttagag aatgtcataa accttttttc taaggtaaaa atagaactta
     5881 cacttatatt aactttgata ctattaacct taaggtttca tgcatttaca agtaataaaa
     5941 tgttttacaa cactaattta ataatctaca attttataat t
//
LOCUS       DAMJVG010000133         5964 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.138, whole genome shotgun sequence.
ACCESSION   DAMJVG010000133 DAMJVG010000000
VERSION     DAMJVG010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5964)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5964)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5964
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.138"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            104..670
                     /locus_tag="PC512_003527"
     CDS             104..670
                     /locus_tag="PC512_003527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HDF2443223.1"
                     /translation="MSVSLQKGQRVSLVKDNNPVKNLVVGLGWDMNKLGKKNYDLDAF
                     AIALTNQDKMNVRGDLVYFGNLKHPSKAIIHTGDNLTGKGEGDDEQIIVNLEDIPEYV
                     HKIVFGVSIYKAKKRDQDFGQMNNSFIRLIDSNSKQELFKYNLQEDFSGKVTVLAGEI
                     YRRNEEWKFNALGIGQNEELRELINTYK"
     gene            710..1291
                     /locus_tag="PC512_003528"
     CDS             710..1291
                     /locus_tag="PC512_003528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HDF2443224.1"
                     /translation="MGITLAKGQKVSLTKSNPGLKKVIVGLGWDINKYDGGFDFDLDA
                     SAFLTGTDGKVTNDGDFIFYNNLKHASGAVEYMGDNRTGVGDGDDEQINVDLSKIPQN
                     IAKISFSVTINEAITRRQNFGQVENSYIRIYNEETNEELIKYELGEDFSIETAIVVAE
                     LYRHNGEWKFNALGSGFEDGLAGLCKNFGVNIG"
     gene            complement(1348..2265)
                     /locus_tag="PC512_003529"
     CDS             complement(1348..2265)
                     /locus_tag="PC512_003529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF2443225.1"
                     /translation="MTIRSLEIFVKVAECGKMSEVARNMYITQSSVSQAISEIEKEYG
                     VKLFDRISKKLYLTEAGKKLLGYGRHLLAVNEEMNDCMKHCAKNIRIRVGATVTVGTC
                     VISPIMLELYKVNPLIEPEVFVEDTRLIAKKLLNSELDIAIVEGKIKHPDIVTKSIIN
                     DNLVLICSHKHEFYKRDSIKVSELSNQPLIMRELGSGTRAQLEKQLKELKIPMNIRWS
                     CYNSEAILRAVVDNFGIAVISELLIEDYLKKHLLWACDIEGINLHRTFDIAYHRSKFF
                     TENISAFFDISVEYGKKQARKKSRSVNSL"
     gene            2395..4026
                     /locus_tag="PC512_003530"
     CDS             2395..4026
                     /locus_tag="PC512_003530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDF2443226.1"
                     /translation="MKVLIIGGVAAGTKTAAKIKREMGDNCSVTILNKGDDISYAGCG
                     LPYYVGKIIEDKSSLIVNTPESFSKLTGAEVRCGVEVTSIDRNAKQVTLKTLSTGEKE
                     NLSYDKLVIATGADPIKPPIPGIDLPGVFFVRTPNDAIKLRDSIENGIKRAVVIGGGF
                     IGLEIAENLSAMGIRVSVVDMAEHVMPGFDTDFAEYVENHMADKGIMIFTGDQVVGIE
                     GENKVEKLRTKNRAIKTDLVVMSVGIRPNTGFLKDTGLEFAPNNTIIADEYMLTNDKD
                     IYVVGDCAFVKNSLTNKPTWSPMGSSANHEGRICAQNISGKSKTYNGVLGTTVVKLPE
                     LNAGKTGLSKEIAEKEGYNVCSVTIATDDKAHYYPGASNFIIRMVAEKNTRKLLGVQV
                     MGPGAVDKIVDIAATAITLGADLYSLESMDLAYAPPFSTAIHPFVVAVNVLQNKLNGE
                     LDSVLLDEIEDFDSWTKLDVSKAPSIPSLRYIPVGEINGEIEGLAKDEKILLICAKGK
                     NSYMAQNRLRRFGYTNTKVLEGGILFYPNLKVMEE"
     gene            4029..4976
                     /locus_tag="PC512_003531"
     CDS             4029..4976
                     /locus_tag="PC512_003531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013378669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(4Fe-4S)-binding protein"
                     /protein_id="HDF2443227.1"
                     /translation="MSNVTAEQKKEVKGRGFLPSRDGEHFAARIITVNGVINASQAKK
                     IAEAAEKFGNGQLAFTTRLTVELPGVKFEDIEALSEFIASENLITGGTGSRVRPVVAC
                     KGTVCVHGLADTQALAAEIHEEFYKNWYDVKLPHKFKIGVGGCPNNCIKPDLNDLGIV
                     GQRVPDYDSELCVGCKKCAVVEVCPVKAAKLTDKGKLEIDSNLCNNCGKCIESCNFDS
                     IEEKESGYKVYIGGKWGKSVRPGTQIDRLFSKEELMTLIEKAILLFREQGNTGERFGI
                     TIDRIGADKFIEMLLSDEVLERKEEILEALLHLTGGAVC"
     gene            complement(5261..5524)
                     /locus_tag="PC512_003532"
     CDS             complement(5261..5524)
                     /locus_tag="PC512_003532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1883 domain-containing protein"
                     /protein_id="HDF2443228.1"
                     /translation="MEYSYSKMNLKKGDIVEVNLEKQANVILLDHINYVKFKNQRNYD
                     YYGGFAKKNPCRMRVPNTGTWYLVVNQDGNSGIVNFSINTIQN"
     gene            complement(5623..5868)
                     /locus_tag="PC512_003533"
     CDS             complement(5623..5868)
                     /locus_tag="PC512_003533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443229.1"
                     /translation="MFIDEELEGYILTCKISEDFKNIPEYSDEEFYVTVYKDESSDSG
                     YYALLENKEERVVWDGEVVANNIFNNLWIVINKVKTG"
BASE COUNT         2142 a          817 c          981 g         2024 t
ORIGIN      
        1 taaatatagc caacttagcc taaatacgta tataatatag ctaatatggt tcttatactt
       61 gataccatca ataaaactaa aaatataaaa aggagaactt aaaatgagtg ttagtttaca
      121 aaaaggacaa agagttagct tagtaaaaga taataatcct gtaaaaaatc tagtagtagg
      181 cttaggatgg gatatgaata aattgggtaa aaaaaattat gacctagatg catttgcaat
      241 agcattgact aaccaagata aaatgaatgt tagaggtgac ttggtttatt ttggaaatct
      301 taaacaccct tctaaagcta ttatacacac tggagataac ttaactggaa aaggtgaagg
      361 tgatgatgaa caaataattg ttaatttaga agacatacct gaatatgtac ataaaatagt
      421 ttttggagtt tctatataca aagctaaaaa aagagaccag gattttggtc aaatgaacaa
      481 ctcttttata agattaattg attcaaattc caagcaagaa ttatttaaat ataatcttca
      541 agaagacttt tctggtaaag taacagtttt ggcaggagaa atttatcgta gaaatgaaga
      601 atggaaattt aatgctttag gaattggtca aaatgaagag cttcgtgaat taattaatac
      661 atataagtaa taattacaat aaaaaattta taatgaggag ttggtttaaa tgggtataac
      721 tttagcaaaa ggacaaaaag taagtttaac aaaaagtaac cctggtctaa aaaaagtaat
      781 agtaggacta ggatgggata ttaataaata tgatggtggc tttgatttcg atttagatgc
      841 ctctgcattt ttaactggaa ctgatggaaa agtaacgaat gatggagact ttatattcta
      901 taataattta aaacacgctt ctggagctgt tgaatatatg ggtgataata gaacaggtgt
      961 tggtgatggt gatgatgaac aaataaatgt agacttatct aaaatacctc aaaatattgc
     1021 taaaatatca tttagtgtta ctataaacga agcaattaca agaagacaaa atttcggaca
     1081 agttgaaaat tcatatataa gaatatataa tgaagaaact aatgaggaac ttattaaata
     1141 tgaattgggt gaagatttta gcatagaaac agcaatagtt gtggcagaac tatatagaca
     1201 taatggagaa tggaaattta atgctttagg ttctggattt gaggatggac ttgcaggatt
     1261 gtgtaaaaat tttggcgtta atataggcta atatatctaa ataaaaataa gagtatattg
     1321 atatactctt atttttattt agatatatta taaactgttt acacttctac tcttctttct
     1381 cgcttgtttt ttcccatatt ctactgaaat atcaaaaaat gctgaaatat tttctgtaaa
     1441 aaacttgctt ctatgatatg caatatcaaa tgtcctatgt aaattaatac cttcaatatc
     1501 acaagcccac aaaagatgct tttttaaata atcctcaata agtaattcgg atataactgc
     1561 aatgccaaaa ttatctacaa ctgctcttaa tatagcttca gagttataac atgaccatct
     1621 aatattcatt gggattttta attcttttaa ttgcttttct aattgtgctc ttgtaccact
     1681 tcctaattca cgcataatta atggttgatt tgaaagttct gaaactttta tagagtctct
     1741 tttataaaac tcatgcttgt gtgaacatat aagtacaaga ttatcattaa taatgctttt
     1801 tgtaacaata tctgggtgct taatttttcc ttctacaatc gcaatatcta attcactatt
     1861 aagtaatttt tttgcaatca gtcttgtatc ttctacaaat acttcaggtt ctataagagg
     1921 atttaccttg tataattcta acattattgg acttattaca catgtaccaa cagttactgt
     1981 tgccccaact cttatacgga tattttttgc acaatgcttc atacaatcat tcatttcttc
     2041 atttacagct aaaagatgcc tcccatatcc aagaagtttt ttccctgcct cagttaaata
     2101 taattttttt gaaattctat caaatagctt aacaccatac tctttttcta tttctgaaat
     2161 agcttggcta actgatgact gggtaatata catatttctt gctacttcac tcattttacc
     2221 acattcagca accttaacaa agatttcaag actacgaatt gtcatattat cacaacctta
     2281 gcaaacatta gtaaatgctt atgattttat taatatttta gtattttaca aatatattgt
     2341 caagaagtat aattttatta tagagttata aagtagattg gagtgtgata tattgtgaaa
     2401 gtattaatta taggtggagt tgctgctgga acaaaaactg ctgcaaaaat aaaacgtgaa
     2461 atgggtgata attgctctgt tacaatacta aataaaggtg atgatatttc ttatgcaggt
     2521 tgtggtcttc catattacgt tggtaagata attgaagata aatcatcttt aatcgtaaat
     2581 acacctgaaa gtttttctaa actaacagga gcagaagttc gttgtggagt tgaagttaca
     2641 tctattgata gaaatgcaaa acaagtaact ttgaaaacgc tttcaacagg agaaaaagaa
     2701 aatctaagct atgacaaact tgtaattgct acaggggcag acccaataaa accaccaata
     2761 cctggaatag atttacctgg agtattcttt gtgcgtactc caaatgatgc tataaaacta
     2821 agagattcta ttgaaaacgg tattaagaga gctgttgtta ttggtggagg tttcattggt
     2881 cttgaaattg ctgaaaatct ttctgcaatg ggtatacgtg taagtgttgt tgatatggct
     2941 gaacatgtta tgcctggatt tgatactgat tttgctgaat acgttgaaaa tcatatggct
     3001 gataaaggca taatgatttt tacaggtgac caggttgtag gtatcgaagg tgaaaataaa
     3061 gttgaaaaac ttcgtactaa aaatagagct attaaaacag atttagtggt tatgtcagtt
     3121 ggaatccgtc ctaacacagg ttttctaaaa gacacaggtt tagaatttgc ccctaataat
     3181 acaattattg cagatgaata tatgcttaca aatgacaaag atatatacgt agttggagac
     3241 tgtgcttttg taaaaaattc tttaacaaat aaacctacat ggtcacctat ggggtcatct
     3301 gcaaatcatg agggtagaat ttgcgcacaa aatatatctg gaaaatctaa aacttacaat
     3361 ggtgttcttg gaacaacagt agtaaaatta cctgagctca atgcaggaaa aacaggtcta
     3421 agtaaagaaa tagctgaaaa agaaggttat aatgtttgct ctgtaaccat agctactgat
     3481 gataaagctc attattatcc aggtgcatct aattttatta taagaatggt tgctgaaaaa
     3541 aatactagaa aattattagg tgttcaagtt atgggacctg gagcggttga taaaatagta
     3601 gatatcgctg ctactgcaat aactttaggc gctgaccttt attcattaga aagtatggac
     3661 cttgcatatg caccaccttt ttcaacagct attcaccctt ttgtagtggc agtaaatgtt
     3721 ttacaaaata aacttaatgg agaacttgat agtgttttac ttgacgaaat tgaggatttt
     3781 gacagttgga ctaaacttga tgtttcaaaa gctccttcta ttcctagttt acgttatatt
     3841 cctgttggtg aaattaatgg agaaattgaa ggccttgcta aggatgaaaa aattcttctt
     3901 atatgtgcta aaggtaaaaa tagctatatg gcgcaaaatc gcttaagacg ctttggctat
     3961 acaaatacga aagttcttga aggtggaata ctattttatc caaatcttaa ggtaatggag
     4021 gagtaaatat gagtaatgtt acagcagaac aaaaaaagga agtaaaaggt agaggttttc
     4081 taccaagcag ggatggagaa cattttgcag cacgtataat aactgtaaat ggtgtaataa
     4141 atgcatcaca agcaaaaaaa attgcagaag ctgctgaaaa attcggaaac ggtcagttag
     4201 catttactac tagactaaca gtagaattac ctggtgtaaa atttgaagat attgaagctc
     4261 taagtgaatt tattgctagc gaaaatctaa taacaggtgg aactggatca agggttcgtc
     4321 ctgttgtggc ttgtaaaggt actgtttgtg ttcatggtct agctgataca caggcacttg
     4381 ctgctgaaat acacgaagaa ttttacaaaa attggtatga tgtaaaacta cctcataagt
     4441 tcaaaattgg tgttggtgga tgccctaata actgtattaa acctgaccta aacgatcttg
     4501 gaattgttgg tcaacgtgta cctgactatg attcagagct ttgtgttggt tgtaaaaaat
     4561 gtgctgttgt agaggtctgt cctgttaaag cagctaaatt aacagataaa ggtaaacttg
     4621 aaatagatag taatctatgt aataactgtg gtaagtgtat agaaagttgt aattttgata
     4681 gtattgaaga aaaagaatct ggttataaag tctatatagg agggaaatgg ggaaaatcag
     4741 ttcgtcctgg aacacagatt gatagattat tttcaaaaga ggaacttatg actttaattg
     4801 aaaaagcaat tcttttattt agagaacagg gtaacacagg tgaacgtttt ggaataacta
     4861 tcgatagaat cggtgctgat aaatttatag aaatgctttt atcagatgaa gttttggaaa
     4921 gaaaagaaga gatactagag gctcttttac accttacagg tggagctgta tgctaacaat
     4981 aaatatttta attgtacaga taacctatgg aaaaaatttt agttaagaat aattaaaatt
     5041 ctatatatga tatatgataa atgaggctat ctcaaaacac agatacgcct ttttttcatt
     5101 gttgaaatga taaagtatat ttgagttcat ataaaaaaga gtgtctcgtg aattataaaa
     5161 ttcattttga ggcacccaca ttattttata ataattgctt attaatttta ttttaactat
     5221 ataaaaagta caaaaagtaa gaatatccaa tattctaaaa ttaattttga attgtattga
     5281 ttgaaaagtt tactattcca ctatttccat cttgatttac tactagatac catgttccag
     5341 tattaggaac tctcattcta catggatttt tctttgcaaa tccaccatag taatcataat
     5401 ttctttgatt tttaaatttc acataattta tatggtctaa caatattaca ttggcttgtt
     5461 tctctaaatt tacctctaca atatcccctt tttttaagtt catcttacta taactatatt
     5521 ccattgaatt actcctccag tatcgaataa tctttgttat ttactcatct caaatatgta
     5581 aaaattcatt taaaatatta caaatactat ataattagac tattatccag ttttaacctt
     5641 atttattaca atccaaaggt tattaaaaat attattggca acaacttctc catcccatac
     5701 aactctttct tctttatttt ctaataaagc atagtaccca gagtcagaac tttcatcttt
     5761 atagactgta acataaaact cttcatcact atattcaggt atatttttaa agtcttcaga
     5821 tattttacat gttaatatat aaccttctaa ttcttcatct ataaacaaag caattcctcc
     5881 aatctctata tttttactaa ttataccata ttatgtcata aactttttat tttattacaa
     5941 atttctattt tttctttact ttat
//
LOCUS       DAMJVG010000134         5750 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.139, whole genome shotgun sequence.
ACCESSION   DAMJVG010000134 DAMJVG010000000
VERSION     DAMJVG010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5750)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5750)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5750
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.139"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            124..1236
                     /locus_tag="PC512_003534"
     CDS             124..1236
                     /locus_tag="PC512_003534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDF2443230.1"
                     /translation="MNAFIRKRNKNYVVYLEFEDEKTGKRKQKNMGTFDKKREASKRL
                     NEVKESLYNDGFLVPSEITVSEFLLDFLNKYSENISLATYNNYVSICKNYINPSIGKY
                     KIQDLHPVHIQNYIDKLSYKLNPQSIKIHINILKLAIKRAYRLKLIKENVMDSIEAPR
                     YKKFKNEIYDREQMIKLLDLAKNTEMELPINLAIGLGLRISEVLGLTWDNIDFEENTI
                     TVNKITSRINGSVILKEPKTESSVRKISSPKELMSLLKEYKIKQNKNLLKSSIRNNNN
                     LLFFNKKCEPIAEDVMSKKFKRFLEKNELPHIRFHDLRHSHVTLLINSKVPIKVISER
                     VGHSNISTTLSVYSHVLKEMDKEASDKISESLFNAN"
     gene            complement(1444..1920)
                     /locus_tag="PC512_003535"
     CDS             complement(1444..1920)
                     /locus_tag="PC512_003535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443231.1"
                     /translation="MVKKRLVAVVISLAMISVGNFSYAHSGGHNSSGDHHNKNKSELT
                     RYYCGGHSAHQHNKGFCPYASTKENSGVTISSVHNEKNHKNYFAEKGYNKGYEDGCKG
                     LYNLSVTEAKSDNLYEKEILKSSYEKGYLIGYNEYKAKKVDDVMKKMLDIPMLASI"
     gene            complement(2119..3744)
                     /locus_tag="PC512_003536"
     CDS             complement(2119..3744)
                     /locus_tag="PC512_003536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2443232.1"
                     /translation="MLQVTGVGLRFGDKELFKDVNLKFTKGNCYGIIGANGAGKSTFL
                     KILSGEIEPNTGSISITDKERMSVLKQDHFEYEEETVLNVVIRGHERLWNIMKEKDAL
                     YMKEDFNEEDGIKAAELEGEFAELDGWDAETNAEKILMGLGITKDMHYKQMKELVGGE
                     KVKVLLAQSLFGKPEILLMDEPTNHLDFKSINWLNNFIMDLEESIVIIVSHDRHFLNQ
                     ICTNIVDVDFGKIQMYVGNYDFWYESSQLALQLAKDQNKKTEEKIAQLKEFIARFSSN
                     ASKAKQATSRKKQLEKLEVEDIQPSRRRYPYVGFTPAREIGNEVLEVHNLTKTIDGVK
                     VLDNVSFRLDRDDKVVFMGDEIATTALFNIVMGELEPDSGEYKWGVTTSQDYLPKNHN
                     KFFDGVEYSLVDWLRQFSEEKSESFIRGFLGRMLFSGEEALKEAQVISGGEKVRCMLS
                     KLMLSNANVLVLDDPTNHLDLESITSVNKGLEKFPGVLLFTSHDHEFISTIANRIIEI
                     TPNGIMDRKMDFDEYLESKEIQDQLAKMYGKDK"
     gene            complement(4082..5101)
                     /locus_tag="PC512_003537"
     CDS             complement(4082..5101)
                     /locus_tag="PC512_003537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-binding protein"
                     /protein_id="HDF2443233.1"
                     /translation="MKLIKTIDAVGQVLCHDITQIIPGEFKGRKFKKGHIVKEEDIPV
                     LLSLGKDNLYVWEKSEGMVHENEGALFLKELTAGENLDFSEIKEGKIDFIAACDGLLK
                     IDVDALFDLNCVGEIMMATLHNNFIVNKGLKVAGTRVIPLVIDEKKLEDAKKVVGNRK
                     IVNVVPFKPKKVGIVTTGNEVFYSRIVDKFGPVIEEKVKGFGCEVIGQTICPDDKEII
                     KSAIKEFISQGAELICCTGGMSVDPDDVTPTAIKETGADLVTYGSPILPGAMFLLAYY
                     GEVPIMGIPGCAMYHKTTVFDIVLSRVLIDEKLDKYDIARYGHGGLCMNCDVCTYPAC
                     NFAKI"
     gene            complement(5098..5667)
                     /gene="mocA"
                     /locus_tag="PC512_003538"
     CDS             complement(5098..5667)
                     /gene="mocA"
                     /locus_tag="PC512_003538"
                     /EC_number="2.7.7.76"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor cytidylyltransferase"
                     /protein_id="HDF2443234.1"
                     /translation="MINAVIMASGFARRMGANKLLLNYKGCSIIEHVFREVSKIDFHQ
                     VVVVSQYEEVLLLCNKYGFEYIDNKNANIGQSESIKLGVLNSSKCDGYMFFVGDQPFI
                     DNLYIDKIINTFKLDRDFIVIPRYKDMCGNPVIFPYSKKEELLALKEDEKGKTILKNS
                     SKIKYVEVPKEMLFDIDTKMDYERIGGKL"
BASE COUNT         1962 a          966 c          594 g         2228 t
ORIGIN      
        1 atatatacat tttttaaata aatatataca atgtattaaa atgtatgcaa ctctatttca
       61 aaattatttt gtgatatata tatgttataa taaatgtata aaattttgat tggtgggtta
      121 tatatgaatg catttattag aaaaagaaat aaaaactatg ttgtttacct ggaatttgaa
      181 gatgaaaaaa caggtaaaag aaaacaaaaa aatatgggta cttttgataa aaaaagggaa
      241 gcaagtaaaa gactaaatga ggtaaaagaa agcttatata atgatggttt tttagtacca
      301 agcgaaatta cagtgtcaga atttctatta gattttctaa ataaatatag tgaaaatata
      361 tctttagcta catataataa ttatgttagt atttgtaaga attacattaa tccatctatt
      421 ggaaaatata aaatacaaga cttacatccg gttcacatac aaaactacat agataaacta
      481 tcttataaac taaatcctca atcaattaag attcatataa atatattgaa acttgcaata
      541 aaaagagctt atagactcaa attaataaaa gaaaatgtta tggatagtat agaggctcca
      601 agatataaaa aatttaaaaa tgagatttat gatagagaac aaatgataaa attattagat
      661 ttagcaaaaa atacagaaat ggaattacct attaatttgg ctattggatt aggtcttaga
      721 atttcagaag ttttaggtct aacttgggat aatattgatt ttgaagaaaa tacaataaca
      781 gtaaataaga taacttcccg aattaatggt tctgttattc tcaaagagcc aaagacagaa
      841 agctctgtta gaaaaatatc ttctcccaaa gaattaatgt ctttattaaa agaatataaa
      901 ataaaacaga ataaaaattt attaaaatct tccattagaa ataataataa tttgttgttt
      961 ttcaataaga aatgtgaacc tattgctgaa gatgttatga gtaaaaaatt taaaagattt
     1021 ttagaaaaga atgaattacc tcatattaga ttccatgatt taagacactc acatgttact
     1081 ttacttataa attctaaagt acctataaag gttatatccg agagagtagg acactcaaat
     1141 ataagtacta ctctaagcgt ttattctcat gtacttaaag aaatggataa ggaggcttct
     1201 gacaaaattt ctgaaagttt atttaatgct aattaatatt aatttatctt agctttaaat
     1261 tagcttagct tattgagata gattcattaa tattaaatgt atctatctca aattaataac
     1321 tacttaaata atctgtttta ttttaattta tcgcctcagt tattatactt ttttacgaaa
     1381 aattatactt tacaataaaa aagatattcc cttatagaaa atatcttttt aaatactata
     1441 ttattatata cttgctaaca ttggaatatc taacatcttc ttcattacat catctacttt
     1501 ttttgcttta tattcattgt atccaattaa atatcctttt tcatatgaac tttttaaaat
     1561 ctctttttca tataaattat cagatttggc ttctgtgaca cttaaattat aaagcccttt
     1621 acacccatct tcataacctt tattataccc tttttctgca aaatagtttt tatgattttt
     1681 ttcgttatgt actgaagata ttgttactcc agaattttct tttgtactag cataaggaca
     1741 aaaaccttta ttgtgttgat gtgctgaatg tcctccacaa taataacgtg ttaactctga
     1801 tttattttta ttatgatgat ctcctgatga attatgccct cctgagtgag catatgaaaa
     1861 attccctaca ctaatcatag ctaaactaat tactacagct actaaccttt tcttaaccat
     1921 aatctattcc ccccaaaatg ttatatattt ttattatatc atctactata ttatatttaa
     1981 attcttaata tacaaaatat tactctattc tgctaataaa catgtttaaa caacataaaa
     2041 aacctcctaa tatttgatta aaaatttaca cactcatgca tagcatgtct caaatattaa
     2101 aaggttttat actaataatt atttatcttt tccatacatt ttagctaatt ggtcttgtat
     2161 ctctttactt tctaaatact catcaaagtc catttttcta tccattattc catttggagt
     2221 tatctctata attctatttg ctatagtaga tataaattca tggtcatgag aagtaaataa
     2281 aagcactcct gggaactttt caagtccttt atttacagaa gttatacttt ctaggtctaa
     2341 gtggttggta gggtcatcta atacaagtac atttgcattt gaaagcatta gcttactaag
     2401 catacatcta accttttctc ctccagatat aacttgagct tcttttaatg cttcttcacc
     2461 tgagaataac attctaccta aaaatcctct tataaaactt tcactttttt cttcagagaa
     2521 ctgtctaagc cagtcaacca aagaatattc tactccgtca aaaaacttat tatgattttt
     2581 tggaagataa tcttgagaag tagttactcc ccatttatac tctccactgt ctggttcaag
     2641 ttctcccata actatgttga aaagtgcagt agtagctatt tcatctccca taaatactac
     2701 tttatcatct ctatccaatc taaatgacac attatcaaga accttaaccc catctatagt
     2761 tttagttaaa ttgtgtactt ctaaaacttc attcccaatt tctcttgcag gtgtaaatcc
     2821 tacatatgga tatcttcttc ttgatggttg tatatcttca acttctaatt tctctaactg
     2881 tttctttctt gatgttgctt gtttagcctt tgaagcatta gaactaaatc tagctataaa
     2941 ttcctttaat tgagctatct tttcttcagt ctttttattt tggtccttag ccagttgtaa
     3001 agccaattga cttgactcat accagaaatc atagtttcca acgtacattt gtattttacc
     3061 aaaatctacg tcaactatat tagtacatat ttgatttagg aaatgtctat catgtgatac
     3121 tattataact atagattctt ctaaatccat tataaaatta tttaaccagt ttattgattt
     3181 aaaatctaag tggtttgtag gttcgtccat taatagtatt tcaggcttac caaaaagtga
     3241 ttgtgctaac aataccttaa ccttttcccc accaactagt tccttcattt gtttgtaatg
     3301 catatctttc gttatgccaa gacccataag tattttctca gcattagttt ctgcatccca
     3361 tccgtcaagc tctgcaaact caccttcaag ttcggcagct tttatcccat cttcttcatt
     3421 aaagtcttcc ttcatataca atgcatcttt ttctttcatt atgttccaaa gtctctcatg
     3481 acctcttata acaacattta aaacagtttc ttcttcatat tcaaagtggt cctgttttaa
     3541 aactgacatt ctttctttat cagttataga tatactacct gtattaggct ctatttctcc
     3601 tgataatatt tttaaaaaag tagattttcc cgcaccatta gctcctatta ttccatagca
     3661 attaccttta gtgaatttta agttaacatc tttaaatagt tccttatcac caaatctaag
     3721 tccaacacct gtaacttgta acattaatat attttccttt ctttttgctc ataatttatt
     3781 ttatcataaa actttgataa catttttatt atatattatc acgtaaatag tatatttttt
     3841 atactaaatt tgtgaaatat ttattaaaat aatactaaaa attgtaaatt tataaaaatt
     3901 aacaatctct tatattatac ttataaagaa atcaaattgc aactttattc attcttttac
     3961 acattgaaaa taagttatta taatttctaa ataaatatgc ttttcttaaa acatcattct
     4021 agctgttttg tttcatattt aaaaagagta cttaatttgt aaatactctt ttttaataac
     4081 tttatatttt agcaaaatta catgcaggat aagtacatac atcacagttc atacaaaggc
     4141 caccatgacc atatctagct atatcatact tatcaagctt ttcatcaatt aaaaccctag
     4201 ataaaactat atcaaatact gtagttttgt gatacattgc gcatcctggt atacccataa
     4261 ttggaacttc tccataataa gcaagtaaaa acatagctcc tggtaatatt ggtgaaccat
     4321 atgtcactaa atcagctcca gtttctttta tagctgttgg tgtaacatca tctgggtcta
     4381 cactcatccc accagtacaa cagataagtt ctgctccttg acttataaat tcttttattg
     4441 cactctttat aatttcttta tcatctgggc atatagtctg tcctataact tcacaaccaa
     4501 agccttttac tttttcttct attacgggtc caaatttatc aacaattctg ctataaaaca
     4561 cttcatttcc tgtagtaaca attcctactt tcttaggttt aaaaggtact acatttacta
     4621 tttttctatt accaactact ttttttgcat cttctaattt tttctcatct ataactaaag
     4681 gtatcactct tgttccagct acttttaaac ctttatttac tataaaatta ttatgaagag
     4741 tagccatcat tatttctcca acacaattca aatcaaaaag tgcatcaaca tctatcttta
     4801 atagaccatc acatgctgct ataaaatcta ttttcccttc ttttatttca ctaaaatcta
     4861 aattttctcc agcagttagt tcttttaaaa acaatgcgcc ttcattttca tgaaccattc
     4921 cttctgactt ttcccataca tacaaattat ctttaccaag agataataac actggaatat
     4981 cttcttcttt tactatgtgg ccctttttaa attttcttcc tttaaattct ccaggtatta
     5041 tttgagttat gtcgtgacat aaaacttgtc caacagcatc tatagttttt attagcttca
     5101 taatttaccc ccaattctct cataatccat ttttgtatcg atatcaaata acatttcttt
     5161 aggaacttct acatacttta tttttgatga attttttaaa atggttttac ctttttcatc
     5221 ttctttaagt gccaacaatt cttctttctt actatatggg aatatgactg gatttccaca
     5281 catatctttg tatcttggaa ttactataaa atctctatct aatttaaaag tatttataat
     5341 tttatctata tataagttat caataaatgg ctggtctcct acaaagaaca tataaccatc
     5401 acattttgag ctatttaaaa ctcctaattt tatagattca ctttgaccta tatttgcatt
     5461 tttattatct atatattcaa aaccatattt attacacaat aacaaaacct cttcatattg
     5521 acttactact acaacttgat gaaaatcaat cttgctaact tctctaaata catgttctat
     5581 tatagaacag cctttataat ttaataaaag tttatttgct cccattcttc tggcaaagcc
     5641 tgatgccatt atcactgcat ttatcatata tatcatcctt ggtatttata atatattgat
     5701 agttctatga tttttataat atctctattg atattatcta tatatataat
//
LOCUS       DAMJVG010000135         5717 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.140, whole genome shotgun sequence.
ACCESSION   DAMJVG010000135 DAMJVG010000000
VERSION     DAMJVG010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5717)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5717)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5717
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.140"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            49..900
                     /locus_tag="PC512_003539"
     CDS             49..900
                     /locus_tag="PC512_003539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase"
                     /protein_id="HDF2443235.1"
                     /translation="MKNIISAKELISKLEKNDNLVVIDCRFDLINRTYGIDSYKKGHI
                     KGSFILDIDKDLSSPTKEHGGKNPLQDPLILKEKLEKMGVDNDTTIVTYDDGDLNGAC
                     RLFFQLKHLGLKNVYVLDGGITSFVKEGGELEEKVNIPSCTGKEIRPNINNGLVVPME
                     YVKSKLYKKDTVIIDCRANERYQGLVEPAYSKAGHIPSAKNYFCKDLIKSDFENGSLK
                     DIEFLKKFFKDLNNYDEVILSCGSGISACVNSLALRELDIPHKIYIGSFSDWISYDDN
                     EIKTGQE"
     gene            complement(1033..2646)
                     /gene="ggt"
                     /locus_tag="PC512_003540"
     CDS             complement(1033..2646)
                     /gene="ggt"
                     /locus_tag="PC512_003540"
                     /EC_number="2.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyltransferase"
                     /protein_id="HDF2443236.1"
                     /translation="MKFNAYQHKYSSIRNVVYAKNGAVATSTPLASQAGLEILKKGGN
                     AVDAAVATAATLAVVEPTSNGIGGDAYALVWIEEEKRLYGLNSSGFAPENMELKNYNN
                     MKEMPKYGFGAVTVPGIPAAWSELNKKYGKLSLMECLSPAINYAREGYVVSPNVAKVW
                     KKSYELYEKELIGEEFKPWFDTFSKDGKAPEAGDIFICEEQASTLEEIANTQAESFYR
                     GRLADKIDEYSKKFNGAIRKSDLECFYPTWVEPISTEYKGYKIFEIPPNGHGITVLMA
                     LNILKELELEGNIENVEDIHKIIESLKLAFADSKTYVTDIEHMKVKIQELLSQEYAKK
                     RSLLIDNKEALYPTAGEPYCGGTVYLCTADKDGNMVSYIQSNYINFGSGIVIPRTGIA
                     LHSRGNNFNLDPKHHNVVKPFKKPYHTIIPGFLGKEDKAIGPFGVMGAFMQPQGHIQV
                     LTNMIDFGLNPQEALDAPRWQWIKGKEIEVEPEMPKHIIDSLIEKGHEIKVIHDTVDM
                     GRGQIIFKTEQESYICGTESRCDGHIAVY"
     gene            complement(2871..4808)
                     /locus_tag="PC512_003541"
     CDS             complement(2871..4808)
                     /locus_tag="PC512_003541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2443237.1"
                     /translation="MTLFRIAMQNVKNSFFNYLMYFISIVFSVFVFFSFKSIEYNEAL
                     SSLGEKTRMSINTSSIVIVVFVFLFIYYSNSFFFNRRRREVGTYSLLGMRKNQIGKIF
                     LYETFLMGIVAILIGIFLGLLFSKLMTMMLVKLMNEMIVVNMNLSIKALVQTLAVFLI
                     IFIVIGIRNTIVIRNKRIIELFNKYPEKYKFKKFIKLKCVLGVLLIAISYLMSISYFI
                     AENIMLSVFILVTIIPGTFLFFSSTMYMIIDAVKKRKSFYYKGQNLIAFSELGFKLKS
                     NSSVLAVIAILIATSVTMLGFTISLYYDIDRNISENYKYSYTINLGNSYVNNEIDKLL
                     YKYKKDNKIIFDKIIELIDKDINIEMYYKNRNSYIEDRTSVDIIRESDFKKLRQYQNN
                     NYEELTSKESVYYVSDSYKKIFFKDFEIEKINLHIKDANEYDINLFKVQKSILEPEIN
                     SQATFDLIVVKDDVFNQLKLHGNSRLIRLIDIKNEKKELDLTLKLKNIVSENMKFTYP
                     FNFTSSIESYDNLIKLSGLMLFIGIFLSVVFLLCTGSIILFKQLSNIYDDKERYIMLI
                     KLGANNKDIEKIISKQLKVIFLMPLVVGTVHNLFAMSIAQKFIPRSLLVPIIITLVIY
                     FIGYFIYYFLTLKYALNMIKE"
     gene            complement(4795..5562)
                     /locus_tag="PC512_003542"
     CDS             complement(4795..5562)
                     /locus_tag="PC512_003542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003722224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2443238.1"
                     /translation="MEEILSVENIKKEYGRKGSKHEALRGITFKVYKGEFVGIMGSSG
                     AGKSTLLNIISTIDLPSSGDIYINGKNTIKMKQNELADFRRDNLGFVFQDSNLLDTLT
                     IKENIMLPLSLKNERVSVIENRIKEISKELNIESILDKYPGEVSGGQKQRGAVCRAIA
                     TKPSLVLADEPTGALDSKSARDLLNCLLKLNKDSNKTILMVTHDAISASFCNRILFIK
                     DGIIFTEIVKGESNREFYNKIVNTVSLIGGVNKNDFI"
BASE COUNT         1931 a          919 c          641 g         2226 t
ORIGIN      
        1 ttaatataaa ttaaaataaa gataatataa acacaggagg tacattcttt gaaaaacatt
       61 atttcagcaa aagaacttat atcaaaacta gaaaaaaatg ataatctagt tgtaatagat
      121 tgcagatttg atcttatcaa tagaacttat ggtattgatt cttataaaaa aggacacatc
      181 aaaggcagct ttatcttaga tatagacaag gatttatcat ctcctacaaa agaacatggt
      241 ggtaaaaatc ctttacaaga ccctttaata ctaaaagaaa aattagaaaa aatgggtgtt
      301 gataacgaca ctacgattgt aacttatgat gatggagatt taaatggagc ttgcagatta
      361 tttttccaat taaaacattt ggggcttaaa aatgtctatg tactggatgg gggaataaca
      421 tctttcgtaa aggaaggtgg agaattggaa gagaaagtga atataccaag ttgtacaggt
      481 aaggaaatta gaccaaatat aaacaatggt ttagttgttc caatggaata tgttaagtct
      541 aaattataca aaaaagatac tgtaataata gattgccgtg ctaatgagag ataccagggt
      601 ttagttgaac ctgcttactc aaaagctggt catataccaa gtgcaaaaaa ttatttttgt
      661 aaggatttaa taaaaagtga ctttgaaaat ggctcactta aagatataga atttttaaaa
      721 aaattcttta aagatttaaa taattatgat gaagtaattt tatcttgtgg ttcagggata
      781 tctgcttgtg ttaacagtct tgctcttaga gaactggata tacctcacaa gatttatatt
      841 ggtagcttta gtgactggat tagttatgat gacaatgaaa tcaaaactgg tcaagaataa
      901 ggctcataat ctatataaaa tcagcatatg atagcttaaa ttttgtaaag gcgtcagtca
      961 ttgtagactt tcgcctttac taattatttc atatactctt taaatttatt atatatattt
     1021 tagttgataa tattaataaa ctgcaatatg accatcacat cttgattccg tcccacaaat
     1081 ataactttcc tgttctgttt taaatattat ttgacctcgt cccatgtcga cagtatcatg
     1141 aattactttt atttcatgac ccttttcaat taatgaatct attatgtgct ttggcatctc
     1201 tggttcaact tctatttcct ttccttttat ccactgccat cttggagcat ctagcgcctc
     1261 ttgtggattt aatccaaaat caatcatatt tgttaacact tgaatatgtc cttgtggttg
     1321 cataaaagct cccattacac caaatggacc tattgcttta tcttctttac ctaaaaatcc
     1381 aggtattata gtatgataag gttttttaaa tggttttact acattgtggt gtttagggtc
     1441 taaattaaaa ttatttcctc tactatgtaa agcaatccca gttcttggta tcacaattcc
     1501 tgaaccaaaa tttatgtaat tgctctgtat atatgaaacc atatttccat ccttatctgc
     1561 agtacaaagg tatactgtac caccacaata tggctctcct gcagttggat acaaagcctc
     1621 tttattgtca atcaataaac ttcttttttt agcatactct tggcttagta attcctgaat
     1681 ctttaccttc atatgctcta tatcagttac atatgtttta gaatctgcaa aagctaattt
     1741 taaactctct ataattttat gtatgtcttc tacattttct atatttcctt ctaattccaa
     1801 ttcttttaat atgttaagtg ccattaaaac tgttattcca tgaccatttg gtgggatttc
     1861 aaatatttta tatcccttat attctgtact tataggttct acccatgttg gataaaaaca
     1921 ctctaagtca ctctttctta tagccccatt aaatttttta gaatattcat ctattttatc
     1981 agcaagtctt cctctataaa agctttcagc ctgagtattt gctatctctt ctaatgtact
     2041 tgcctgttct tcacatataa atatatctcc agcctctgga gctttaccat ctttagaaaa
     2101 tgtatcaaac catggtttga actcttctcc aataagttct ttttcataga gttcatatga
     2161 ttttttccat accttagcta cattaggaga tactacgtat ccctctcttg catagtttat
     2221 cgctggagat aagcattcca ttaagctaag tttaccatat tttttattta attctgacca
     2281 agctgctggt attccaggta cagttactgc tccaaaccca tattttggca tttctttcat
     2341 attattataa ttttttaatt ccatattttc tggagcaaag ccactagaat ttaaaccata
     2401 caatcgtttt tcttcctcta tccaaacaag ggcatatgca tctcctccaa tcccattgct
     2461 tgtaggttct actactgcta atgtggcggc tgttgcaact gctgcatcaa cagcatttcc
     2521 accctttttt agtatttcaa gtccagcttg agatgctaat ggtgttgatg ttgcaactgc
     2581 tccattttta gcatacacga catttcttat tgatgagtat ttatgttggt aggcattaaa
     2641 cttcataaat ttcagctcct cgtcattttt tatttgatat tctgcttaga tttattatat
     2701 aacatcaatt aatgtaactg atacaaaatg atataaaata tagacttttt cctaacttta
     2761 attttatctt taaataaata tcttaaactc aattctagta ttttctatct gcacttaaat
     2821 aagttatttt attcaaaaca tatatctaat tcttttaact taaaaataat ttattctttt
     2881 atcatgttta gagcatattt taaagttaaa aaataatata taaaatatcc tataaaataa
     2941 atgactagag ttatgataat tggtacaagt aatgaccttg gtataaactt ttgtgctata
     3001 gacatagcaa ataaattatg aactgtacct acaactaatg gcattaaaaa tataactttt
     3061 aactgttttg atattatttt ctcaatatct ttattatttg ctccaagttt tattaacata
     3121 atatatcttt ccttatcatc atatatattt gataattgtt taaataagat tatactacct
     3181 gtacataaaa gaaatactac agacaaaaat atgcctataa acagcattag accacttaat
     3241 tttatcaagt tatcataact ttcaatactt gatgtaaaat taaaaggata agtaaatttc
     3301 atattttcac ttactatatt ttttaatttt aaagtcaaat ccagttcttt tttttcattt
     3361 tttatatcaa ttaatcttat taatctagaa tttccatgta attttaactg attaaatacg
     3421 tcatctttta ctacaattaa atcaaacgta gcttgtgaat ttatttctgg ctccaagatg
     3481 cttttttgta ctttaaacag atttatatca tactcatttg catctttaat atgcaagttt
     3541 attttttcaa tctcaaagtc tttaaaaaat atttttttgt atgaatcaga aacatagtac
     3601 acagattcct ttgaagttaa ttcttcataa ttgttattct gatattgtct taatttttta
     3661 aaatcacttt ctctaataat atctacagac gttctatctt ctatataact atttcgattt
     3721 ttataataca tttcaatatt tatatctttg tctataagtt ctattatttt atcaaagatt
     3781 atcttattat cttttttata tttatataat aatttgtcaa tttcgttatt tacataagaa
     3841 tttcctaaat ttatggtata actgtattta taattttcac ttatgttcct atctatatcg
     3901 taataaagtg atatggtaaa ccctagcata gttacacttg tagctattaa tattgctatt
     3961 acagccaata cactactatt gctctttaat ttaaatccaa gttcagaaaa tgcaattaaa
     4021 ttctgtccct tataataaaa actttttctc ttcttaacag catcaataat catatacata
     4081 gttgatgaaa aaaataaaaa agttccaggt attattgtaa ctaatataaa aactgaaagc
     4141 ataatatttt cagcaataaa ataactaatt gacattaaat aagaaatagc tattaataaa
     4201 acaccaagta cacattttaa ctttataaat tttttaaact tatacttttc tggatattta
     4261 ttaaataact ctataattct cttatttctg ataactatag tatttcttat tccaataact
     4321 atgaatatta ttaaaaatac cgctagtgtc tgaactaagg cctttatact taagttcata
     4381 tttactacta tcatttcatt cattaatttt acaagcatca tagtcataag ctttgaaaat
     4441 aacagtccta aaaatatacc tattagtatt gcaactatac ccatcaaaaa agtttcatat
     4501 aaaaatattt ttcctatctg atttttcctc attccaagta aactataagt tcctacttct
     4561 cgcctacgtc tattgaaaaa aaatgagttt gaataatata taaataaaaa tacaaatacc
     4621 actattacaa ttgaacttgt attaatactc atcctagttt tctctccaag tgaactcaac
     4681 gcttcattat actctataga tttaaaacta aaaaatacaa atacactaaa tacaattgaa
     4741 ataaagtaca ttaaataatt aaaaaaacta ttctttacat tttgcattgc aattctaaat
     4801 aaagtcattt ttattaactc ctccaattaa ggaaactgta tttactattt tattatagaa
     4861 ctctctgtta ctttctccct ttacaatttc tgtgaatatt attccatcct ttataaagag
     4921 tattctattg caaaaactcg cacttatagc atcatgagtt accatcaata ttgttttatt
     4981 gctgtctttg tttaatttta atagacaatt caacaaatcc ctagcagatt tagaatctaa
     5041 tgctcctgta ggctcatctg caagtactaa tgatggtttt gttgctatag ctctacatac
     5101 agctcctctt tgcttttgtc caccagaaac ttcgccaggg tatttatcta atatagattc
     5161 tatatttaat tcttttgaaa tctcttttat tctattttct attactgata ctctttcatt
     5221 ttttaaagaa agaggcaaca ttatattttc ttttattgta agtgtatcca aaagattaga
     5281 atcttgaaat acaaagccta gattatcacg tctaaaatct gccaattcat tttgcttcat
     5341 tttaatagta ttctttccat ttatataaat atctcctgat gaaggtaaat ctattgtaga
     5401 aataatattt aaaagtgttg atttaccagc accggaagac cccataatac caacaaattc
     5461 tcctttataa accttgaaag ttattcctct tagagcttca tgttttgaac cttttcttcc
     5521 atactccttt tttatatttt caacagataa tatttcttcc atagttaata atcacctttc
     5581 atcacaatta gttatttatc aattctcaca aatatattat atatattaaa atggctttta
     5641 aacatttaat tatattaatt taaggttaca ttttcgtaag tattaattat atttcttcaa
     5701 atttattgca attatgt
//
LOCUS       DAMJVG010000136         5701 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.141, whole genome shotgun sequence.
ACCESSION   DAMJVG010000136 DAMJVG010000000
VERSION     DAMJVG010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5701)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5701)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5701
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.141"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            240..1067
                     /locus_tag="PC512_003543"
     CDS             240..1067
                     /locus_tag="PC512_003543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIM24 family protein"
                     /protein_id="HDF2443239.1"
                     /translation="MDLSKKVKILENASDGKSEFEILEFEKLEGASSPLMAMGLYFAR
                     EAGLKARQIKIKLNNSSIKTEAGALYYYKGNISSETKIGGVGGLFKKGISGALTNESM
                     MKPVYKGTGEVYLEPSFRHYLFMSLDNDSIIVDKGLFYCCSDTIEVKAFTQKNFSSAL
                     LGGEGFFQIELSGTGVIVLECVVPQSEIVEYELKNGEELKVDGNFAIARTSGVNFSVT
                     KSDKSLIGSALNGEGFLNTFTGSGTVWLAPTQVMYEKLSFGAMPTNDNMNNKVSKQK"
     gene            2067..2530
                     /locus_tag="PC512_003544"
                     /pseudo
     CDS             2067..2530
                     /locus_tag="PC512_003544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861860.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(2797..3441)
                     /locus_tag="PC512_003545"
     CDS             complement(2797..3441)
                     /locus_tag="PC512_003545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2443240.1"
                     /translation="MFGQSFQNCLVLIKENFKLSTLTNLICSIILLCMIPLIQGVANL
                     DRISTAICLENYVAIIGIVMLVPVFSLEQSKEIDEIVSSKALSQVIVQLIRILMSIIG
                     IVVLIIGFVNVLIYLGCNFPVVEYIIGSFASAMFIGSLGMFFSNLFNNTIIGYMISIG
                     YLILNMMTKGKYVGKFFIMSMSQGSFDEKYWLILGSVVLIIASLLIKPVKRKIR"
     gene            complement(3371..4660)
                     /locus_tag="PC512_003546"
     CDS             complement(3371..4660)
                     /locus_tag="PC512_003546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2443241.1"
                     /translation="MNLFIKECKNILKSMIYYIFIVVLVFFYISQLGSSVSNDVSKNI
                     PNDGNPLVAPQKVENIEEYYSVHNQYPYGQKESMKTEKVIPNATINLIREYQKNTYTT
                     YPTGVVKYIKLDQNKTKTIEKYIEEITGKSISEINSLWKTDESIKIDYSKVSLERFEE
                     IMQRVDDILGGGSAYAFDKLQRFGVVPVTYDEAMKNYNYTIQKDKVSNGYARIFCDYI
                     GIVLSIFPVFVAVFMSLKDKRSRMREIIYSKQVSSCKIVLSRYFALVFMMILPVLILG
                     MKDLLPLIFFAKDKGISIDNLAFIKYTLWWILPTLMIVTAVGMSITILTDTPVAIIVQ
                     LIWWLYSINSTGLKGDYSTMGLMIRHNSVLNGDIIIQNFNQIMINRIVISLGALVLVL
                     LAIFLYEQKRRGNLDVWAKFSKLFSSNKRKLQIKHFN"
     gene            complement(4657..5529)
                     /locus_tag="PC512_003547"
     CDS             complement(4657..5529)
                     /locus_tag="PC512_003547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2443242.1"
                     /translation="MEMKIAVSNLSKRFGKKQALDNINLEIDSGMFGLLGRNGAGKTT
                     FMRILATLLSKTEGSIHMCGVPIENTKEIRNMVGYLPQDFSMYPNMTVYKAMDYLAVL
                     SDIPLRKRRKIIAKLLSKVNLTNYQNVKVKSLSGGMNRRLGIAQALIHNPRVLIVDEP
                     TAGLDPEERIRFRNLLCEIANDRIVILSTHIVGDIEATCENVAILNSGKVIYNGSTEA
                     LAKLAEGKVYSIEVDKKDIENIKSRFIVIGMLTHGGKAILRIISDDKPFETAVNCNPT
                     IEDGYMLIMGGDNI"
BASE COUNT         2062 a          784 c          705 g         2150 t
ORIGIN      
        1 ataattttaa catgcccata aaatataata cccacaaatg ataaataata ctcaaaatgt
       61 ctattgaaat aactatacat ccttaaataa cttaacttaa atctaaacat ttcaaaaact
      121 tcttaaaaat atgtaaaaat ttgatgataa agtagcgatt ttttcaaaaa aaatgtaata
      181 tagagttata tcttataata ttttagagat aaattttatc atagtgggga gaaatttgta
      241 tggatttaag caaaaaagta aaaattttag aaaatgcatc agatggcaaa agcgaatttg
      301 agatattaga atttgaaaaa cttgagggag cttctagccc attaatggca atgggattat
      361 attttgctag agaagctggt ttgaaagcta gacaaattaa gataaaatta aataattcat
      421 caataaaaac agaagctggt gcattatact attataaagg aaatatatct tctgaaacta
      481 agattggtgg tgttggaggt ctttttaaaa aaggaatatc aggagcactt actaatgaat
      541 caatgatgaa acctgtatac aaaggtactg gagaagttta tttggaacct tcttttagac
      601 attatttatt tatgagtctt gataatgatt ctataattgt tgataaagga ttattctatt
      661 gttgctctga tacaatagaa gtaaaagcat ttacacaaaa gaacttctca tctgctttac
      721 ttggtggtga aggcttcttc caaatagaat taagtggtac tggtgtaatc gttctggaat
      781 gtgttgtacc tcaaagtgaa attgtagagt atgaattgaa aaatggtgaa gaattaaagg
      841 tagatggtaa ctttgcaata gcaagaacat ctggtgttaa tttttctgtt acaaaatcag
      901 ataaatcttt aattggttct gctttaaatg gtgaaggttt cttaaataca tttactggta
      961 gtggtacagt ttggctagct ccaactcaag taatgtatga aaaactaagt tttggagcaa
     1021 tgcctactaa tgataatatg aataataaag tttctaagca aaaatagttg ttttataaat
     1081 atttattaaa tcattattga ttttataaag tcactataaa ttttattaga ttattataaa
     1141 atcagagtgt ggaaatattt atgtgtattc tttaaataaa aatttccaca ttctgtaaag
     1201 ttattatact tgatatataa aattcaattt aggaacatag tctaacattt ataaacatat
     1261 taaggtaatg atttctcttg gtagttattc tcatatctta ttctttgatt atatttatct
     1321 tattcctagc ccttatgtca tattatattt cttatcttat tatttataat tagcattaac
     1381 ttatctaaaa tcttgtattt ttttaatagt aaagtttaca tctatattaa tttcataaaa
     1441 caatcaaggt agtcaagaga ttcaacttta tttgatttta aaaatttaag tgaatttgtt
     1501 cttatacaca cctttttaaa attatatctg tagaaaatat catttagagc tataattaaa
     1561 ttaacttatt aaattttaga aaatttatta aaaaatataa gttaaattaa tatttttaaa
     1621 gattcttttt tgtaactact agaacactaa tttagtagtt attgtatctc taaagtttaa
     1681 gcatggatag atatacattt gataatttgc ctataattta cctactactt ggattattgg
     1741 agcaaataca atatattaat aataagttcc taaaaccaat aaattaacta atacacataa
     1801 agatattgat gttgattata caactataag aaacggattt aacagaattt aatcaagcta
     1861 agaaattata tatatcgtga tgtttttgaa ttagaaggtg attcaaaatt agtttatagt
     1921 cttctgtgaa tccaataaaa agtacagggt acaagaattg ttagtaaaat ttttaaagat
     1981 tttatggata aatataaata gttttactta ttttctaaaa ctttaaaata ccattaatta
     2041 ccttaaatat tttaatagga ggacatatga atttaaataa agttaaattt actgaagaac
     2101 atgctattga agttactaat tggaaatatg aaggtaaata ttcaatatac aatctacctc
     2161 catgggagga aattaaaaag aagaattttt cactagcaaa agaagataaa agaaaaaatt
     2221 ttataagttt tataaatgac aataaagaat tgataggttt tataaactta ttagatgaag
     2281 gaagctctgt attctttggt attggttgaa accgaattat tgtggaatgg gaattggtaa
     2341 agaaataatt agcctaggat tacaagaatg tagaaataaa tatagtacta aaccaattgt
     2401 attaaatgta agaacctgga acatgagagc tgtaaaatgt tatgagtctc aaggatttaa
     2461 aatagttgag actaaggtac aaaaaacgca tttaggagat ggagaatttt ttgttatgag
     2521 gtatcaatag tttataacaa tagtcctatt gttaatacaa caattaaaat gaaaaaatac
     2581 atatgtgtag gtcatagcaa taagtgtctt tgaaatataa atttgagagc ttttgataaa
     2641 attcggtata catatatatt ttatactacg gatatataaa tctatctaca tacataaaga
     2701 gattgtaagt aggtttgtgt atataaaaat agatttatat ttcataaatg tactttttat
     2761 ttgcattacc tttattttat ctaagctctc attttattat ctaatcttcc tttttactgg
     2821 ttttattaag agagatgcaa ttatcaacac aacacttcca agtatcagcc aatatttctc
     2881 atcaaaacta ccttgactca tagacattat aaaaaatttt ccaacatact tgcctttagt
     2941 catcatattt aaaattaaat atcctataga tatcatataa cctatgattg tattattaaa
     3001 taaatttgag aaaaacattc ctaaacttcc tataaacata gctgatgcga aacttccaat
     3061 aatatactca actactggaa aattacatcc aagatatatt aaaacattta caaaacctat
     3121 gattaatacc actataccta taattgacat cagtatccta attaattgta caataacttg
     3181 agataatgct tttgaagata ctatctcatc aatttctttt gattgctcta gcgaaaatac
     3241 aggtaccaac attactatcc ctattattgc aacataattt tctaaacata tagctgttga
     3301 aattctgtct aaattagcta ctccttgtat tagaggaatc atacatagca atataattga
     3361 acatattaaa ttagttaaag tgcttaattt gaagttttct tttattagaa ctaaacagtt
     3421 ttgaaaactt tgcccaaaca tcaagattcc cccttctttt ttgctcatat aagaatatag
     3481 ctaacaaaac aagcaccaat gctcccaaac ttatcacaat tctattaatc ataatttgat
     3541 tgaagttttg tataataata tccccattta atacactatt atgtcttatc attagcccca
     3601 ttgttgaata atcacctttg agtcctgtag aatttatact gtaaagccac caaattaatt
     3661 gcacaataat tgctactggt gtatctgtta atatagtaat actcattcct acagctgtaa
     3721 ctatcataag agttggtagt atccaccata atgtatattt tataaatgct aagttatcaa
     3781 tagatatacc tttatcttta gcaaagaaaa tcaaaggaag taaatctttc atacctaaaa
     3841 ttaatacagg caatatcatc ataaagacaa gtgcaaaata tcttgataaa actattttgc
     3901 atgaagatac ttgttttgaa taaataatct ctctcattct tgaacgctta tctttaagtg
     3961 acataaaaac tgccacaaat actggaaata tacttaaaac tatacctata taatcgcaaa
     4021 aaattcttgc atacccatta ctaactttat ctttttgtat tgtatagttg taattcttca
     4081 tagcttcatc ataggtaact ggaactactc caaatctttg taacttgtca aaagcatatg
     4141 cagaccctcc tcctaaaatg tcgtctactc tttgcattat ttcttcaaat ctttcaagag
     4201 atactttaga ataatctatt tttatacttt catcagtttt ccaaagtgaa tttatttcgc
     4261 taatactttt accagttatt tcttctatat atttttctat ggtcttcgtt ttattttggt
     4321 ctaattttat atacttaact acccctgttg gatacgttgt atatgtgttt ttttgatatt
     4381 ctctaattag gtttatagtt gcatttggaa tgactttttc tgttttcata gattcttttt
     4441 gaccatatgg atattgattg tgtacagagt aatattcctc aatattctct actttttgtg
     4501 gagcaactaa tggatttcca tcattaggaa tatttttact tacatcattt gaaactgaac
     4561 ttccaagttg agaaatatag aaaaaaacta aaactacaat aaaaatataa tatatcatac
     4621 tctttaatat atttttacat tcttttataa atagattcat atattatctc ctcccattat
     4681 aagcatatag ccatcttcaa tagttggatt acaatttact gctgtctcaa aaggtttatc
     4741 atctgatata atcctaagta tagcctttcc accatgagtc aacattccta taactataaa
     4801 tctacttttt atattttcaa tatctttttt atctacttca atactatata ctttcccttc
     4861 agctagtttt gctaatgctt ctgttgagcc attgtatatg acttttccac tattcaatat
     4921 agctacgttt tcacatgtag cttctatatc tccaacaata tgtgtagata aaataacgat
     4981 tctatcattt gcaatttcgc atagtaaatt tctaaatctt atacgttctt ctgggtcaag
     5041 acctgctgtc ggctcatcta ctattaaaac tctgggatta tgaattaatg cttgtgctat
     5101 cccaagcctt ctattcatac ctccagataa agattttact ttcacatttt gataattagt
     5161 aaggtttact ttgcttaata actttgctat aatttttctt ctttttctta gtggtatatc
     5221 cgataaaact gctaaataat ccattgcttt atatactgtc atgttaggat acattgaaaa
     5281 gtcttgtggc aaataaccaa ccatatttct aatttcctta gtattctcaa taggaactcc
     5341 acacatatgt attgaacctt ctgtttttga taataaagtg gctaaaattc tcataaatgt
     5401 ggtttttcct gctccatttc ttcctaaaag accaaacata ccactgtcga tttcaagatt
     5461 tatattatca agagcttgtt ttttcccaaa tcttttacta agattggata ctgctatttt
     5521 catttccata tataaataca cccccagaaa caattttata gaattttatt tttataaatt
     5581 tttactgtat tttcataata aattctaaaa cttaagatat tatttataaa tttctaaatt
     5641 ttttctaaag attttaattt ttctgttttt aattaaatta aagtatcttt gtttctgaaa
     5701 t
//
LOCUS       DAMJVG010000137         5642 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.142, whole genome shotgun sequence.
ACCESSION   DAMJVG010000137 DAMJVG010000000
VERSION     DAMJVG010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5642)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5642)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5642
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.142"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            116..1441
                     /gene="cdeA"
                     /locus_tag="PC512_003548"
     CDS             116..1441
                     /gene="cdeA"
                     /locus_tag="PC512_003548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MATE transporter CdeA"
                     /protein_id="HDF2443243.1"
                     /translation="MENLFTRKFTTFEFLKFVSPAIISMIFISLYTIIDGIFVSTLVG
                     SDALASINIVLPIINLVCGFGIMMATGGGAIVSIRMGENRQDEANSTFSFIVLFSLIV
                     GILFTVISYFFIKEISILLGATDKLLPYCITYGKVMILCTPFYILKFIFEYFARTDGN
                     SKFSLFLSVIGGVTNIILDYVFIKYFGMGLLGAAVATAIGIILTCVLGIIYFLSNKST
                     LKLRKPKTDFRLIRDTMINGSSEMVTELSTGITTFLFNVVALKLAGENGLAALTIVLY
                     AHFLMTSVYLGFAAGVSPLISYNFGAENSDKLKETFKHSLKFIFISSLLVFIIALVFA
                     PFIVRVFVNPDNTVFKLALQGLKIFAFAFLFVGINIFASGFFTAFHNGKISAIISFSR
                     AFVFIIIGIIILPPMLNMTGLWLTVPFAEVITIFISILFIKKYKCRYKY"
     gene            complement(1536..2330)
                     /locus_tag="PC512_003549"
     CDS             complement(1536..2330)
                     /locus_tag="PC512_003549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2443244.1"
                     /translation="MNELKPYIKFFNKNTKLYIIIFMIVGIVMNILPVFILKIFGEAS
                     KTNLSTIVNPILTYITILLFVYGVNIANKDFSGALSIRADRKSCIKAIVIDLIILSFV
                     ISILGIVLIFLSKLFIEIITGYSIELSVLLKRDMIWTSISALIDPSTSSMPLTYLNYF
                     VQICINEICIGFIGVLLGAFTYRVRKVTSITILIGLPILMVIYIVNFATKNMHKMLLY
                     LEKIIYSFQNPFILFGTKVGIIVICIIFIILLLRKAPIKEYANDLL"
     gene            complement(2331..3206)
                     /locus_tag="PC512_003550"
     CDS             complement(2331..3206)
                     /locus_tag="PC512_003550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2443245.1"
                     /translation="MSSSIKIENLSHSFKKQNIFNNMSLNFEKNKIYGLLGKNGAGKT
                     TLLNIMVNQLIQNEGEIEILGKNPKEDIKVLEEVCIVREKEFYSPDFKVGQIFEFSSS
                     FYKSYDKGLEKELCKYFDLNTKKKYKQLSRGMKTILSNIIGICSNSAITIFDEPTIGL
                     DAVNRQEFYNIILDSYIKNPRTIIISTHLIDEIDDLLEHVIILNEGKIIIDEEIDVIK
                     QKAHYITGNKEELEKLECIKNIKPKKAFGNAVAYFYYGDFSENDEKILKNSNIDVGYI
                     GLQDMFVNMTKKEEL"
     gene            complement(3210..3578)
                     /locus_tag="PC512_003551"
     CDS             complement(3210..3578)
                     /locus_tag="PC512_003551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2443246.1"
                     /translation="MKLVLNNEEPIFIQIARAIEDEILSNGIKEEEQVPSTTELSKLY
                     KINPATVLKGINILVDKNILYKKRGIGMFVSDGAKTIIKEARKENFKHNFVKNLLQEA
                     NKLEINREELVDIIINFKED"
     gene            complement(3761..4420)
                     /gene="deoC"
                     /locus_tag="PC512_003552"
     CDS             complement(3761..4420)
                     /gene="deoC"
                     /locus_tag="PC512_003552"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HDF2443247.1"
                     /translation="MKHILKTVDHTILKATTTWEDIKILCDEAVDMSVASVCIPPSYV
                     KRASEYLKGKIKICTVIGFPLGYQTTATKVFEAKDAIENGADEVDMVVNISDIKNKDY
                     DNIGKEIKEIKKAIGDKVLKVIIETCYLDEDEKIKMCEIVTMSGSDFIKTSTGMGTGG
                     ATLEDIKLMKEHVGKNVKIKAAGGVKSISDAEKFIEAGAERLGTSSICKILKNEDTTD
                     Y"
     gene            complement(4456..>5642)
                     /gene="murJ"
                     /locus_tag="PC512_003553"
     CDS             complement(4456..>5642)
                     /gene="murJ"
                     /locus_tag="PC512_003553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HDF2443248.1"
                     /translation="KQEPCDFSHGRFRTGIIFIGITSVMSAFLQIKENFIVVGFGSIP
                     YNIVIIISIMLSTIFGPYILPIGAVVAMVVQLLFYMFFVKKTNYKYLYYLNFKDDSLI
                     KLLALLSPVFIGVAVNQVNSLVDTTLASTLVKGSIPALTYADRLNGFVTGTFTASIVS
                     VMYPMLSKLSAENNQKKFTSSVKSSINMIIISMIPISVASIFFATPVVRIIFERGAFD
                     ARATQMTATALIFYAVGMTAFGLRDILGKVFYSLQDTKTPMVNGIISVGVNIVLDLVL
                     IKPMAHGGLALATSSSSIACILLLFLNLKRKVGYFGQDKIIKATLKSVVASLIMGVLS
                     YFTYKFIFGILGVGTFNEFVSLAISVIVGGGIYTLLMTIFKVEEVDMILNIAKRKLHL
                     KK"
BASE COUNT         1887 a          878 c          625 g         2252 t
ORIGIN      
        1 taatatgatt ttttgttgat tttaagctgt ttatcgtata aataaaattt ttcttgacta
       61 tatagttact atatagctta ttatatatag agagtaataa aaggaggtaa aatttatgga
      121 aaatttattt acaagaaaat tcactacttt tgaatttcta aaatttgttt ctcctgcaat
      181 tatatccatg atatttatat ctttgtatac aataatagat ggcatctttg tatcgacatt
      241 agttggttct gatgctcttg ctagtataaa tattgtacta cctataatta accttgtttg
      301 tggatttgga ataatgatgg caactggtgg aggtgctatc gtttctatac gtatgggtga
      361 aaatagacag gatgaagcca actctacatt ttcttttata gttttgtttt cattgattgt
      421 tgggatttta ttcacagtaa tctcatattt ctttatcaaa gaaatatcta ttttgcttgg
      481 tgcaacagat aagttattac catattgtat aacttatggt aaagttatga ttttatgtac
      541 accattttat attttaaaat ttatatttga gtactttgca agaactgatg gaaattctaa
      601 atttagttta tttctatcag tcattggtgg tgtaacaaat ataatattgg attatgtatt
      661 tattaaatat tttggaatgg gtcttttagg agctgcagtt gcaactgcta taggtattat
      721 tttaacttgt gttttaggta ttatttactt cttatctaat aaatctacac taaaattaag
      781 aaaaccaaaa accgatttta gacttataag agatactatg ataaacggtt cttctgaaat
      841 ggttacagaa ttatctacag gaattacaac attcttattt aatgtagtag ctttaaaatt
      901 agcaggagaa aatggacttg ctgctcttac tatagtattg tatgctcatt ttttaatgac
      961 atcagtctat ctaggattcg ctgctggagt gtctccatta ataagctata attttggtgc
     1021 tgaaaacagt gataaattaa aagaaacatt taaacattct ctaaaattta tatttatttc
     1081 ttctctttta gtgtttatta ttgctttagt atttgcacca tttattgtta gggtctttgt
     1141 aaatccagat aacacagtat ttaaactagc cttacaagga ttaaaaatat ttgcatttgc
     1201 ttttttgttt gttggtataa atatatttgc atcaggattt tttacagcat ttcacaatgg
     1261 aaaaatttca gctattatat cttttagtcg tgcctttgtt tttataatca taggaatcat
     1321 aattcttcct cctatgttaa acatgactgg attatggctt acagttccat ttgctgaggt
     1381 tataaccata tttatatcta ttctatttat aaaaaaatat aaatgtagat ataagtatta
     1441 aaaattaata cttaaaatca acatttatta aaactaataa acctgcttta aaatacaaat
     1501 ttacaaattt gatttttaag caggttttat tttagttata ataagtcatt tgcatactct
     1561 ttaattggtg cttttctaag taataaaatt ataaatatta tgcaaataac tataattcct
     1621 acctttgttc caaataaaat aaaaggattc tgaaatgaat aaataatttt ttctaaatac
     1681 aatagcattt tatgcatatt tttagttgca aaattaacta tataaattac cattaatatc
     1741 ggtaatccta tcaatatagt aatactagta acttttctaa ctctatatgt aaaagctcca
     1801 agtaacactc ctataaaacc tatacatatt tcatttatac atatttgtac aaaataattt
     1861 aaataagtta gtggcatact tgatgttgaa ggatctatca gtgctgatat agatgtccaa
     1921 atcatatctc tctttagtaa aactgatagt tctatactgt aacctgttat aatttctata
     1981 aataacttcg ataaaaaaat caaaactata cctaaaatag aaatcacaaa gcttaaaata
     2041 attaaatcta tgacaatagc ttttatacaa ctttttctat ctgctcttat acttaaagct
     2101 cctgaaaagt ctttatttgc tatatttact ccatacacaa atagcagtat agttatatat
     2161 gttaaaatag gattcacaat cgtggataaa ttagttttag atgcttctcc aaaaatcttg
     2221 agaataaaca ctggcaaaat attcataaca attcccacaa tcataaatat aattatatac
     2281 aatttagtat ttttattaaa aaattttata tatggcttta attcattcaa ttacaattcc
     2341 tccttcttag tcatgttaac aaacatatct tgtagcccta tgtatcctac atcaatattt
     2401 gaatttttaa gtattttttc atcattttca ctaaaatcac catagtaaaa ataagcaact
     2461 gcatttccaa atgccttttt aggttttata ttttttatac attctaattt ttctaactct
     2521 tctttatttc cagtaatata atgagctttt tgttttatga catcaatttc ttcatctata
     2581 ataatttttc cctcatttaa tattattaca tgctccagta aatcatctat ttcatcaatc
     2641 aaatgagttg atattattat tgtccttgga ttttttatat aactatctaa aattatgtta
     2701 taaaactctt gtctatttac tgcatccaaa ccaattgttg gctcatcaaa tatggtgata
     2761 gctgaattag aacaaatacc tattatattt gaaagtatag ttttcatacc tcttgacagt
     2821 tgtttatact tttttttagt atttaaatca aaatatttgc ataattcttt ttctaagcct
     2881 ttatcataac ttttataaaa actagaagaa aattcaaata tctgacctac tttaaaatct
     2941 ggactataaa attctttttc cctgacaata caaacttctt ccaaaacttt tatatcttct
     3001 tttgggttct ttcctaatat ttctatctca ccttcatttt gaattaactg atttaccatt
     3061 atatttaata atgttgtttt tccagctcca ttcttaccta ataaaccata tatcttattt
     3121 ttttcaaagt ttagagacat attattaaaa atattttgct tcttaaaact gtgagataaa
     3181 ttttctatct taatagaact actcatatat taatcctcct tgaaattaat tataatatca
     3241 accaattctt ctctatttat ttctaatttg ttagcttctt gaagtaggtt ttttacaaaa
     3301 ttatgtttaa aattttcttt tctagcttct tttataatag tttttgcacc atctgataca
     3361 aacatcccta tccccctctt cttatataaa atatttttat caaccaatat atttatacct
     3421 tttaatactg tagctggatt aattttataa agctttgaaa gctctgttgt tgatggaacc
     3481 tgttcttctt cttttattcc atttgatagt atctcatctt caattgctcg tgctatctga
     3541 ataaatatag gttcttcatt atttaatact aatttcatag gttcctcctt tctccattag
     3601 ttagttactc aactaattaa ctatataact tataatatct tgaaaaatat tttctgtcaa
     3661 tactaaataa aaaacagagg gaaaattccc tctgtttttt gttctttata tttataatta
     3721 aattttgatt tttgtaatcc tatcccataa gttaaaaact ttaataatct gttgtatctt
     3781 cattttttaa tattttacat attgagctag ttcctaacct ttctgctcct gcctctataa
     3841 atttttctgc atcagaaatt gatttaactc cccctgcagc ttttattttt acattttttc
     3901 caacatgctc tttcataagc tttatatctt ctaaagtagc tccacctgtt cccattccag
     3961 tagatgtttt tataaaatct gaacctgaca ttgttactat ttcacacatt tttatttttt
     4021 catcttcatc taaataacat gtctctataa tgacttttaa tactttatct cctatagctt
     4081 tttttatttc ttttatttct tttcctatat tatcataatc tttatttttt atatctgaaa
     4141 tgtttacaac catatcaact tcatctgctc cattttcaat agcatctttt gcttcaaata
     4201 cttttgtagc agtagtttga tatcccaaag ggaaccctat cactgtacat atctttattt
     4261 taccttttag atattctgat gctcttttca catatgatgg tggtatgcaa actgatgcta
     4321 cactcatatc tacagcttca tcacataaaa ttttaatatc ttcccatgta gttgtagctt
     4381 ttaaaatagt atggtctact gtttttaata tatgtttcat aaaatcctcc taaatttata
     4441 attaatataa ttagattact tttttaaatg caattttctc tttgcaatat tcagtatcat
     4501 atcaacctct tcaactttaa aaatagtcat tagtagtgta taaattccac ctccaactat
     4561 aactgaaata gctagtgaga caaactcatt aaatgttcct actcccaaaa ttccaaatat
     4621 aaatttatac gtaaagtatg ataaaacacc cataattaaa gatgcaacta ccgatttcaa
     4681 agttgctttt attattttat cttgtccaaa atatccaact tttctcttta ggttcaagaa
     4741 gagtaacaat atacatgcaa ttgatgatga actagttgca agagcaagac caccatgagc
     4801 cattggtttt attaaaacta agtccaatac tatatttacc cctacagata taatcccatt
     4861 taccataggt gtttttgtgt cttgtaatga ataaaaaacc tttcccaaaa tatctcttaa
     4921 gccaaatgca gtcataccaa ctgcataaaa aattaaggca gttgctgtca tttgggttgc
     4981 cctcgcatca aaagcacctc tctcaaaaat gattctaaca acaggagttg caaaaaaaat
     5041 agaagcaact gaaataggaa tcatagaaat tattatcata tttatactag atttaactga
     5101 actagtaaac ttcttttgat tattttctgc acttaactta gataacatag gatacataac
     5161 agatactatt gaagctgtaa atgtccctgt aacaaaacca tttaatctat ctgcataagt
     5221 aagtgctgga atgcttcctt taactaatgt tgaggctaaa gttgtatcta ccaatgagtt
     5281 cacttgatta acagcaacac ctataaatac tggtgaaagt aatgctagta atttaataag
     5341 gctatcatct ttaaagttta agtagtataa gtatttgtag ttcgtttttt taacaaaaaa
     5401 catgtaaaag agcagttgaa ctaccatagc aaccacagca ccaattggaa gtatgtatgg
     5461 tccaaatatg gtacttaaca ttattgaaat aattattact atattatagg gtatacttcc
     5521 aaatccaact acaataaagt tctctttaat ttgtaaaaat gctgacataa cacttgtaat
     5581 acctatgaat attattcctg ttctgaacct cccatgacta aagtcacagg gttcctgctt
     5641 ca
//
LOCUS       DAMJVG010000138         5519 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.143, whole genome shotgun sequence.
ACCESSION   DAMJVG010000138 DAMJVG010000000
VERSION     DAMJVG010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5519
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.143"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            44..160
                     /gene="rrf"
                     /locus_tag="PC512_003554"
     rRNA            44..160
                     /gene="rrf"
                     /locus_tag="PC512_003554"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            complement(374..1558)
                     /locus_tag="PC512_003555"
     CDS             complement(374..1558)
                     /locus_tag="PC512_003555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDF2443249.1"
                     /translation="MLSKRLNFITPSYTIGISSKVKEMESNGVKVINLSIGEPDFNVP
                     NNAKSYGIDSLNKDYTKYDLVPGLKILREEICKKLIEENNCNYSIDEIVVSSGAKNSI
                     TNTLLALTDEGDEVLLPKPYWVSYPEMIKLVNAVPVFIDTKKENGFKLTKEELEKSIT
                     DKTKILVINNPSNPTGSVYTKDELIEIVDVCIQNKIYILADEIYEKICYTGEFTSIAS
                     LSEEAKDITITINGFSKSAAMTGLRLGYTASNKTIAKAMSSIQGHLISHPSLTAQYIA
                     YGALKDCSIDIDNMVKTYKSRRDLIKSKLDSIDNVGYVNPNGAFYIFIDLSKVSEKFE
                     YKDSFSIEFCNQFLEEYNVAVVPGIAFGMDKYIRISYACSENTFLSGLDKLKEFVYKI
                     MA"
     gene            1931..4282
                     /locus_tag="PC512_003556"
     CDS             1931..4282
                     /locus_tag="PC512_003556"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside triphosphate reductase"
                     /protein_id="HDF2443250.1"
                     /translation="MVEFVKKRDGRVIPFNEDRITRAIFLAATNVAEREGIVPDYKLS
                     EQLTQEVIKFLNHKYSESVPSVEDIQDSVVKVLIETGHAKTSEEYIIYRTERSRIRNS
                     KTRLMKAIEEITFEDAEDADIKRENANINGNTAMGTMLQYGSTVSKEFCKTHILKPEH
                     SFAHDNGDIHIHDMDFLNMGTLTCCQIDVKKLFNGGFSTGHGFLREPQDIISYGALAA
                     IAIQSNQNDQHGGQSIPFFDYGLAEGVYKTFKKFYIGNLAKALKLFKGIENNDVIKNI
                     VYNTEKETNQKVGLKRDELYLNLEKEKLIQTFDIDDELVNKMQNFAFEESYRETDKKT
                     YQSMEAFIHNLNTMHSRAGAQVPFSSVNFGTDTSEEGRMVTKNLLLSQERGLGNGETP
                     IFPILIFKVKEGINLNPEDPNYDLFKLSCRVSAKRLFPNFSFLDAPFNAKYYKKGEPD
                     TEATYMGCRTRVLSNVCGSETVSGRGNISFTTVNLPRLGIKHGIINNEKANLDGFFEE
                     LDEKINLIIEQLLERLEVQGNKKMKNFPFLMGQGVWKGSDDLGPEDTLKEVIKQGTLT
                     IGFIGLAECLIALIGKHHGESKEAQELGLKIVSHMRHKMDEATDKYKLNFSLMGTPAE
                     GLSGRFTKIDKKVYGEIKGITDKEYYTNSFHVPVYYNISAYDKIEIEAPYHELTNAGH
                     ITYVELDGDPSDNLEAFETVIKAMKDLGIGYGSINHPVDRDPICGFSGVITSNICPVC
                     GRNEDESDIKFERIRRITGYLVGTVDRFNNAKKAEVRDRVKHR"
     gene            4304..4843
                     /gene="nrdG"
                     /locus_tag="PC512_003557"
     CDS             4304..4843
                     /gene="nrdG"
                     /locus_tag="PC512_003557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HDF2443251.1"
                     /translation="MKIRMSSTISYDSIVDGPGLRMVIWTQGCIHNCKECHNPQTHDL
                     CGGFYMDTEEIINKVKSLKLQKGITLSGGEPFLQPEPLEEIAKEAKINGLDVWSYTGF
                     TFEQLLDKKNRAYFKNLNLLKQIDILVDGKFIAEKKDISLKFRGSSNQRIIDVQKSLK
                     YKQVFLVEQYMKDDLSIAE"
BASE COUNT         2150 a          624 c          888 g         1857 t
ORIGIN      
        1 aaacttatta aaaacttaat agaaatatta agcataaaga ttatgtggtt acaatagcag
       61 agaggataca cctgttccca ttccgaacac agaagttaag ctctctagcg ctgatggtac
      121 ttggtgggaa actgcctggg agagtaggac gtagccacgt aatttttttg ttataataaa
      181 tttagaattt aacttatata gtttaatttg ataatttgat gaaaaaaata aaagacttat
      241 tgatttttaa atctataggt cttttatttt ttatctaaca tttaaattaa gttgttgaat
      301 atatcttata ttacttacct tatatattaa ttatcattaa tacattatat ctaattacta
      361 ttcatctaaa ttattatgcc attattttat atacaaattc ttttaattta tctaatccag
      421 ataagaaagt attttcactg caagcatagg atatacgaat atatttatcc ataccaaatg
      481 ctatgccagg aacaactgca acattatatt cttctaaaaa ttgattacaa aattctatag
      541 aaaaactatc tttatattca aatttctcag atactttaga aagatctata aatatataga
      601 atgcgccatt tggattcaca tatcctacat tatcaataga gtctagtttt gatttaatta
      661 aatctcttct tgatttatat gttttaacca tattgtctat gtcaattgag caatctttca
      721 aggctccata ggctatgtat tgtgctgtta gacttgggtg agatataaga tgtccttgta
      781 tagaactcat tgctttagca atcgttttat tagatgcagt atatcctaat cttaatccag
      841 tcattgcagc tgacttagaa aaaccattta tagttattgt tatatcttta gcttcttcgc
      901 ttaatgatgc aattgatgta aattcaccag tgtagcatat tttttcatat atttcatctg
      961 ctaaaatata tattttattt tgtatgcata catctactat ttctattaat tcatcttttg
     1021 tataaacact accagtagga tttgaaggat tgtttattac aagaattttt gttttatctg
     1081 ttatagattt ttcaagttct tcttttgtta acttaaatcc attttctttt ttagtatcaa
     1141 taaaaactgg aacagcatta actaacttaa tcatttcagg ataactaacc caataaggct
     1201 ttggtaataa gacttcatct ccttcgtctg ttaaagctag taaagtattt gttattgagt
     1261 tttttgctcc acttgataca actatttcgt ctattgaata gttacagtta ttttcttcaa
     1321 taagtttttt acagatttcc tctctaagta tttttaatcc tggaactaaa tcatatttag
     1381 tgtaatcttt atttaaagaa tcaataccat aagattttgc gttattaggt acattaaaat
     1441 cgggttctcc tatactaaga tttattactt taactccatt actttccatt tctttaactt
     1501 tagaactaat acctattgtg taggatggtg ttataaagtt tagtcttttt gataacataa
     1561 aatgcctcct tttaaattat tatttatatt atacgacaaa tttaaagaat ttacataagg
     1621 aaatttgtag atatatacat taatatatat aatagcctac actttttgcc taaaattagt
     1681 gtaaaaaaaa gagaaaaaaa ttttaacttt caaagttgtt agaaacgcta ctgttcaaaa
     1741 tatccacata gtatttgcaa tgatttgcgc aagtttgact attatgtaca aatttggtaa
     1801 tcttaatata gcaattatta agataatccc tttaacttag ttgaagggga tttttttaga
     1861 cttaacatac tacatatagt ggtatgggga ttaataaaat acaatatata gtaacaggag
     1921 gtttttttaa ttggttgaat tcgtaaaaaa aagagatgga agagtaattc catttaatga
     1981 agatagaata acaagagcta tatttttagc agcaacgaat gttgcagaaa gagaaggaat
     2041 agtacctgat tataaattat ctgagcaatt aactcaagaa gtaataaagt ttttaaatca
     2101 taaatactca gaatcagttc caagtgttga agatatacaa gattctgtag ttaaggttct
     2161 tatagaaact ggccatgcaa aaactagtga agaatatata atatacagaa ctgaaagaag
     2221 tagaataaga aattcaaaaa caaggttgat gaaggcaata gaggaaatta cctttgaaga
     2281 tgcagaagat gctgatataa aaagagaaaa tgcaaatatt aatggtaata cagcaatggg
     2341 aactatgtta caatatggaa gcactgtatc taaagaattt tgtaaaacac atatattaaa
     2401 accagagcat tcttttgctc atgataatgg agatatacac atacatgata tggatttttt
     2461 aaatatggga acattaactt gttgtcaaat agatgttaaa aaactattca atggtggatt
     2521 ttcaacagga catggctttt taagagagcc acaagatata ataagttatg gtgcattagc
     2581 tgcaattgct atacaaagca atcaaaacga tcaacatgga ggtcaaagta taccattttt
     2641 cgattatgga ttggctgaag gtgtatataa gacatttaag aaattctaca taggaaattt
     2701 agctaaagca ttaaagttat ttaaaggaat tgaaaataat gatgtgataa agaacatagt
     2761 atataataca gagaaagaaa caaatcaaaa agttggtctt aagagagatg aattgtatct
     2821 aaacttagaa aaagagaaat taatacagac ttttgatata gatgatgaac ttgtaaataa
     2881 gatgcaaaac tttgcatttg aagaatcgta tagagaaact gataaaaaaa catatcaatc
     2941 tatggaagca tttatacaca atctaaacac aatgcactct agagcaggtg cacaggtacc
     3001 attttcaagt gtaaacttcg gaacagatac ttctgaagaa ggaagaatgg taactaagaa
     3061 tcttctatta tctcaagaaa gaggtttagg taatggagag acaccaattt ttccaatttt
     3121 aatatttaag gtcaaagaag gcataaattt aaatcctgaa gaccctaatt atgatttatt
     3181 taaattatca tgcagagtat cagctaaaag actattccct aattttagtt ttttagatgc
     3241 gccttttaat gcaaaatatt ataaaaaagg tgaaccagat acagaagcta catatatggg
     3301 ttgtagaaca agagtactta gtaatgtgtg tggttcagaa acagttagtg gtagaggaaa
     3361 catatctttt actacagtaa atttaccaag attgggtata aaacatggta ttataaataa
     3421 tgaaaaggct aatttagacg gtttctttga agaattagat gagaagataa acttaattat
     3481 agaacaatta ttggagcgcc ttgaggtaca aggaaataaa aagatgaaga attttccatt
     3541 cttaatgggg caaggtgtat ggaaaggttc tgatgattta ggaccagaag atacactaaa
     3601 agaagtaata aaacaaggaa cattgacaat tggatttata ggtttagcag agtgccttat
     3661 tgctcttata ggtaaacatc atggagaaag taaagaagct caagaattag gattaaaaat
     3721 agtgtcacat atgagacata aaatggatga agcaacggac aaatataaat taaatttctc
     3781 cttaatgggt actccagcag aaggtctttc aggtaggttt actaaaatag ataaaaaagt
     3841 ttatggagaa attaaaggta tcacagataa agaatattat actaattcat tccatgtacc
     3901 agtttattac aatataagtg catatgataa aattgagata gaagctccat accatgaatt
     3961 gactaatgca ggtcatataa catatgtaga gttagatgga gatccatctg ataatttaga
     4021 agcttttgaa actgttataa aagctatgaa agatttgggt ataggatatg gaagtataaa
     4081 tcatcctgta gatagagacc caatatgcgg tttttcaggt gtaataacaa gtaatatatg
     4141 ccctgtatgt ggaagaaatg aagatgaaag tgatatcaaa ttcgaaagaa taagaagaat
     4201 aacaggatat ttagttggta cagttgatag atttaataat gctaaaaaag cagaagtaag
     4261 agatagagta aaacatagat agttttattt gggggaataa gttatgaaaa taagaatgtc
     4321 atctactata agttatgaca gcatagttga tggaccagga ttaagaatgg taatatggac
     4381 ccaaggatgt attcataatt gtaaagagtg ccataatcct cagacacatg atttatgtgg
     4441 aggattttat atggatacag aagaaattat aaataaagtc aaatcattga aattacaaaa
     4501 aggcattacg ctatcaggag gagaaccatt tttacaacca gaaccattag aagaaatagc
     4561 aaaagaagct aaaataaatg ggttagatgt atggtcatat actggattta cgtttgaaca
     4621 actgttagat aaaaaaaata gagcgtattt taaaaattta aatttactaa agcaaattga
     4681 tattttagtg gatggaaaat ttatagctga aaaaaaagat ataagcttaa agtttagagg
     4741 gtcatcaaat caaaggataa ttgatgttca aaaaagtttg aaatataaac aagtgttttt
     4801 ggttgagcaa tatatgaagg atgatttatc tatagcagaa taaaatataa ataaacagga
     4861 ttaaatatat gcatatattt aatcctgttt attttcatat aatatttcaa gcttgtataa
     4921 tgtaacaatt aaaccaaaag actcattgta tatttgaaat taagtttttt atagtttata
     4981 ggtgttttat gtggattacg aatgatatag tattgataca ttatttaata gattcttatg
     5041 ccaagaaaca attaatttat agaaattctt aattgttaca atataaatat ctagatatgt
     5101 tataagatac tgataaataa tttataaagt ttattaatct aatattgtgt gtgaatatta
     5161 agtggtcaag tagtctaaaa aatgaaaaag atttaaaaaa gtgttttaac taaacacata
     5221 agtgttaaat tcatgtataa gtataggtta gatacataag aaataattat gtaatatcta
     5281 tctttgtaaa aaaatattaa attttgtaat ttgtggataa atatgtttat aatgtggata
     5341 atatttaatg taataagtta aagcaatatg aatcaactgt ttataatgtg gataatatta
     5401 taaatgtatg aataattgca gtatttaaaa acaaaaaaag ttaaaaaagt tgttgactct
     5461 aaaagaaaaa gttggtatag taatacttgt cctcaagaaa agggcaaaca aataaagca
//
LOCUS       DAMJVG010000139         5333 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.144, whole genome shotgun sequence.
ACCESSION   DAMJVG010000139 DAMJVG010000000
VERSION     DAMJVG010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5333)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5333)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5333
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.144"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            277..2289
                     /locus_tag="PC512_003558"
     CDS             277..2289
                     /locus_tag="PC512_003558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2443252.1"
                     /translation="MKKSVALVNDSRKDLIDFLENNLKLVFGDSININRYFINEINDN
                     DIINDDVILVMSVERLDKIINNILDKKKVIVVRRTFREDKIYNLLSLPQGTNVLIVND
                     SDETTLETISLFYKIGVTNIRPIPYMNDNNYKNIKIAITPGVPEKVPSFISDIFDLGH
                     RYIDISTFIEIINLLQIDSKEIQSNLVKYSEEIISLDTGIKDKYKELFLKIEELDTIL
                     NLSKDGILFTSKDGEINTYNSKVKDILDINEDIYGKYIEDIFVDSLKVLLSEKEILDK
                     VVVFNKKYINVNKKNIYNRDEKMGTYYSLQEITYIKKLEQNLTKKLREKGQIAKYTFK
                     DIKTNSPKMFECIDLAKKVSKSDLSILIRGESGTGKELIAQSIHNNSNRKNQPFIAVN
                     CAAVPENLLESQLFGYDKGTFTGGLKDGKQGLFELANNGTIFLDEIGDMPLELQTKLL
                     RVLQEKQIMPVGSHNVINIDVRIISATNKNLEQMIDNSQFREDLYYRLNTIPINIPPL
                     RERKEDILIIMEDLINKKLVITPEAKKLIQNYMWKGNIRELQNVTSYLNIMCEDIVLE
                     KDLPPNLRSSDNKNTSLKLKYSKNDILNILEILILNKESDVGIGRGLILKALLDKNLQ
                     ITEGKIKKIFEYLKKEELIICSSGRYGSKITQKGEDFYNKLKYKGL"
     gene            2658..3878
                     /locus_tag="PC512_003559"
     CDS             2658..3878
                     /locus_tag="PC512_003559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2443253.1"
                     /translation="MQQALKLKYQTKELGKDFVIESCNSIKPWLINIRRELHKIPELA
                     LEENLTKQKVISYLKEIGIDYMEFTKHNGIMAYILKESADKTICIRADMDALPIEEEN
                     NIPYKSIHSGKMHACGHDAHTTMLLGACKVLHSIKDKLNVNVKFLFQPAEEGFGGAKF
                     LVEDGCLENPKADYIFGLHVMPHIETGLIETKYDTLNASVDTIKISIKGKRAHGAYPE
                     NGIDAIVTASQIVTSLQTIISRNLEPNNAVVLTIGKIYGGDAHNVICEDVKLEGTLRT
                     LNSKTRNFMIDKIAKIVGDTASAFGCVGTLHVSDENYPAVINEKELVDTVISNTKELL
                     GEEKFILRPNPSLGGEDFSFYTEHCKGAFFHLGCKNEEKGLISPLHTSSFNIDEDCLP
                     IGVMMHVMNTLYFN"
     gene            3915..5264
                     /locus_tag="PC512_003560"
     CDS             3915..5264
                     /locus_tag="PC512_003560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDF2443254.1"
                     /translation="MEKAKKLGLFSMILLGINSIIGSGIFLLPGKVYNLAGQNSMFIY
                     IFATLLVLSILLCFAEVGSMFDKKGGAYLYSKKAFGDFIGFEVGTMSWVIRIISWSTL
                     AVGFATALGSFWPESATEYKGYIAAILVTLLSINSLFGIKSTKIMNNVITIAKLVPLI
                     VFIIVGIFFIKFVNIVPSGNVVNSSMGPAIILVFYAFTGFESFIVASGEMENPKKNLP
                     VALITTIFICAIIYILIQIVCMGILGDRLFENSIPIADASSVFVGNYGKVFISVATLI
                     SIFGINIGSSIVTPKCGSSLAEEGSLPAFIGKTNKYGAPYVAIIISLICCIPLVLTGS
                     FEQLAVMSVIARFAQYIPTCLSVIVLRKRTDVKASFKIPFGPVIPIVAILGSLWLLQQ
                     AWAEDISKPITQNRVLIGLGAMLLIAPLYIFMKKNKEIEHKNKSEDSKLYISREKIQ"
BASE COUNT         2192 a          589 c          812 g         1740 t
ORIGIN      
        1 attatcaata gaatttatta aaataaattt ttttgggtgt atattataat ttaatcgaat
       61 agaaatgaaa aatatacata cagtttaagt tttaagcaac aattaggggg atttggtgac
      121 aagattttta actataagaa agaaagtgtc ttaatgcaac ttttagaaag tcattataga
      181 cactttcttt tttatttgat aaatttaaat tatcaaaatt agattgcttt atacaactat
      241 tttgttggaa actatttatt atataaggag aaataaatga aaaaatcagt agctctggta
      301 aatgatagta gaaaagattt aatagacttt ttagaaaata atttgaaatt agtttttgga
      361 gattctataa atattaatag atacttcata aatgaaataa atgataatga tattataaat
      421 gatgatgtga tattagtaat gtcagtagaa agattagaca aaattataaa taatatacta
      481 gataagaaaa aagtgattgt ggtaagaaga acttttaggg aagataaaat ttataatcta
      541 ctatctttac cacagggtac aaatgttcta atcgtaaatg attctgatga aactactcta
      601 gaaactataa gtttatttta taaaattgga gtgactaata ttagaccaat tccatatatg
      661 aatgataata actataaaaa tataaaaata gctataactc caggagttcc agaaaaagta
      721 cctagcttta tctcagatat atttgattta ggtcacagat atatagatat ctctacattt
      781 atagaaataa taaatttatt acaaattgat tcaaaggaaa tacaatctaa tctagttaaa
      841 tactcagaag aaataataag tttagatact ggtataaaag ataaatataa ggaattattt
      901 ttaaaaatag aagaattaga tacaatcttg aatttatcaa aagatggtat attatttact
      961 tcaaaagatg gtgaaataaa tacatataat agtaaagtaa aagatatttt agacataaat
     1021 gaggatatat atggaaaata cattgaggat atatttgtag atagtttaaa agttttattg
     1081 agtgagaaag agatactaga taaagttgtc gtattcaata agaaatatat aaatgtaaat
     1141 aaaaaaaaca tatacaatag agatgaaaaa atgggcacat attatagttt acaagaaata
     1201 acatacataa aaaaattaga acaaaatctc actaaaaaat taagagaaaa aggacaaata
     1261 gcaaaatata catttaagga tataaaaaca aatagtccta aaatgtttga atgtatagat
     1321 ttagctaaga aggtttctaa atctgattta agcatactta tcagaggtga aagtggaact
     1381 ggtaaagaac tcatagctca gtctatacat aacaactcaa atagaaaaaa tcaacccttt
     1441 atagcagtaa attgtgcagc cgttcctgaa aatttattag aaagccagct attcggatat
     1501 gacaagggaa cttttactgg aggtctaaaa gatggaaaac aaggattatt tgaacttgct
     1561 aataatggaa caatattctt agatgaaata ggcgatatgc ctttagaatt acaaacaaaa
     1621 ctacttagag ttcttcaaga aaagcagata atgcctgttg gatctcacaa tgtaattaat
     1681 atagatgtta gaatcatatc tgctacaaat aagaatttag aacaaatgat tgataatagc
     1741 caatttagag aggatttata ttatcgatta aatacaattc caataaatat acctcctcta
     1801 agagaaagaa aagaagacat attaattatt atggaagatt taattaataa gaaattagta
     1861 atcacaccag aagcaaaaaa acttatacaa aactatatgt ggaaaggtaa tataagagaa
     1921 ctccaaaatg ttacatccta tttaaacatt atgtgtgaag atattgtatt agagaaagat
     1981 ttacctccaa acttaaggtc ttcagataac aaaaatacat cattaaaact aaaatatagt
     2041 aagaatgata tattgaatat attagagata ctaattttaa ataaggaatc agatgttggt
     2101 attggtagag gattaatttt aaaagcacta ctcgataaga accttcaaat tacagaagga
     2161 aaaattaaaa aaatatttga atatctaaaa aaagaagaac ttataatttg tagttcagga
     2221 agatatggaa gtaaaataac tcaaaaagga gaagattttt acaataaatt aaaatataaa
     2281 ggtctataaa attataattt atcaaacaaa gaaatctatt caggattaaa gtactccttc
     2341 aataggtttt tttatttttc aagtacccta aaattataat ttattttgta cataaataat
     2401 aggaattaat aggaatagga taattttttt atttcctatt ttttttatat aaactagcat
     2461 ataaaatata ttttcttcaa aataatattt tttactgaaa attgaaacta tgcaatcatt
     2521 ttttatacta tacatataga taaatgatta tatttattca atattcttat aaaaaacaaa
     2581 attctccatc gaaaattatg gcataataat tgcttattat attaataaaa caataaaaag
     2641 caattggagg aataaaaatg caacaggctt tgaaattaaa atatcaaacc aaagaattag
     2701 gaaaagattt tgtaatagaa agttgtaatt ctataaaacc atggcttata aacataagaa
     2761 gagaattaca taaaattcca gaattagctc ttgaagaaaa tcttactaaa cagaaggtaa
     2821 tttcttattt aaaagaaatc ggaattgatt atatggaatt tacaaaacac aatggaatta
     2881 tggcatatat tttaaaagaa agtgcagata aaacgatttg tataagagca gatatggatg
     2941 ctcttcctat tgaagaagaa aacaacatac cttataaatc aatacattct ggaaaaatgc
     3001 atgcttgtgg ccatgatgca catacaacca tgctacttgg agcatgtaaa gttttacatt
     3061 caataaaaga taaacttaat gtaaatgtaa aattcttatt tcaaccagca gaagaaggtt
     3121 ttggaggagc aaaattttta gttgaggatg ggtgtttaga aaaccccaag gccgattata
     3181 tattcggact tcatgttatg ccacatatag aaacaggcct tatcgaaaca aaatatgata
     3241 cattaaatgc tagtgtagac actataaaaa taagtatcaa aggtaaaaga gctcatggtg
     3301 catatcctga aaacggtatt gatgcaatag ttacagcttc acaaattgtt acatcattac
     3361 aaactataat aagtagaaac ttagaaccaa ataatgctgt tgttttgact ataggtaaaa
     3421 tatatggtgg tgatgcacac aatgtaatat gtgaagatgt aaaattagaa ggcactttaa
     3481 gaaccttaaa tagcaaaaca agaaacttta tgattgataa aatagctaaa attgttggag
     3541 atactgcatc tgcatttggt tgtgttggga ctttacatgt aagtgatgaa aactatcctg
     3601 ctgttataaa tgaaaaagaa ttagtagata cagttatatc aaatactaaa gaattacttg
     3661 gagaggaaaa atttatattg agaccaaacc cgtctttagg tggtgaagac ttttcttttt
     3721 acacagaaca ttgtaaagga gcattcttcc atttaggatg taaaaatgag gaaaagggct
     3781 taatttcacc tcttcatacc tctagcttta atatagatga agattgttta ccaataggtg
     3841 ttatgatgca tgtaatgaat actttgtatt ttaattagta cagtaattaa taaaagaata
     3901 ggagataaat taatatggaa aaagctaaga aattaggtct atttagtatg atattattag
     3961 ggattaatag cataataggt tcaggtatat tcttactacc aggtaaagtt tataatctag
     4021 caggtcaaaa cagtatgttt atatacattt ttgctacact cttagttcta tcaatacttt
     4081 tatgttttgc agaagttgga agcatgtttg ataagaaagg aggagcatat ctatactcca
     4141 aaaaagcttt tggagatttt ataggatttg aagttggtac aatgtcttgg gttattagaa
     4201 ttatatcatg gtctactcta gcagtaggat ttgcaacagc tttaggttca ttttggccag
     4261 aatctgccac tgaatacaaa ggttatatag ctgcaatact cgtaacacta ctttcaataa
     4321 atagcttatt tggaattaaa agcacaaaga taatgaataa tgtaataact atagctaaat
     4381 tagtaccatt aatagttttt ataatagttg gaatattttt tataaaattt gtaaatattg
     4441 ttccttcagg aaatgtagtt aactctagta tgggtccagc cattatatta gtattttacg
     4501 catttaccgg ctttgaatca tttattgtgg caagtggaga aatggaaaat cctaaaaaaa
     4561 atcttccagt cgcattaata accacaatat ttatatgtgc aataatttat atattaattc
     4621 aaattgtctg tatgggtata cttggagata gactatttga aaacagtatt ccaattgcag
     4681 atgcttcaag tgtatttgta ggcaattatg gtaaagtttt catatctgta gcaacattaa
     4741 tatctatatt tggtataaat ataggttcat caatagtaac tcctaaatgt ggttcttctc
     4801 tagcagaaga aggttctctt cctgcattta taggaaaaac aaataaatat ggtgctccat
     4861 atgtagcaat aataatatct ttaatttgtt gtataccact tgtgctaact ggaagttttg
     4921 aacaacttgc agtaatgagc gtaattgcaa gatttgctca gtacatacca acttgtttat
     4981 cagtaatagt tttaagaaaa agaacagatg ttaaggcctc ttttaagatt ccatttggcc
     5041 ctgttatacc aatagtagct attttaggta gcttatggtt gttacaacaa gcttgggcag
     5101 aagatatttc aaaacctata actcaaaata gagttttaat aggattaggg gcaatgttgt
     5161 taatagctcc tctatatata tttatgaaaa aaaataagga aatcgagcat aaaaataaat
     5221 cagaagattc taaattatat atttcgagag aaaaaattca ataatatttt atactattac
     5281 ttctcataaa atataataaa tataaaaaaa ttgtagataa aactatttta taa
//
LOCUS       DAMJVG010000140         5324 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.145, whole genome shotgun sequence.
ACCESSION   DAMJVG010000140 DAMJVG010000000
VERSION     DAMJVG010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5324)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5324)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5324
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.145"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            127..963
                     /locus_tag="PC512_003561"
     CDS             127..963
                     /locus_tag="PC512_003561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF2443255.1"
                     /translation="MNIKKIFNNNVVVSSLEDGTEIIVTGAGVGFKKKVGDLIDENLI
                     SKKYFVQDDQRDKYNQILNKTSIEYFKISEEIIEKANEVLNTQVNDSIILALTSHIEF
                     AVQREKQGIKLPNLILNETKQLYREEFEFGLWAIDEIEKRIGIKLPEDEAGYIAIHII
                     NGLENSQKDEGINILEFSKQVIQIIEEVHGFKLDVNSLNYTRLITHLKFFVQRILRKE
                     TYNDSDIEDMYKLVNKNYNKPKVCTEEIVALVLDRFEYKISKEEELYLMIHINKITNS
                     GC"
     gene            1316..2893
                     /locus_tag="PC512_003562"
     CDS             1316..2893
                     /locus_tag="PC512_003562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDF2443256.1"
                     /translation="MKKNKLGLWNFFQMLGKTFMFPIALLSVSGMMLGLGAGFTDPKM
                     IEMVPFLGNEYVNLVLNFMLTIGLFAFNNLGALFAMAIPLGLLKKEKEFGAFSGLVGF
                     IAMHIGTNFYLTRADLLVPAEQMSTNGQAMIMGIQTYNTSVLGGIVAGLIVYAIYDKV
                     SNLKIPESLGFYSGPRLVPIVSLIVMSIVGLLIPIVWPPFFNAFQSLGRWISSAGPLG
                     YFSYAVAERVTIPFGLNHLVTSVFRFTPIGGTAVIDGETYFGTLNMFMAYVENNQIIP
                     LDLAGKMEQGKLMIQYGLAGAALAIYRTAKPENRKALKGLLISGVLTVIIGGISEPIE
                     FLFLFISPALFAFHTFMNGIANMVLPYLGVLMGFTGDLIAFISFGVLRGTATGWPIAV
                     LVAVLYFAIYYFVFKWAIIKFNIKTPGREDKEIKVSEGNGSDFKNLSTYKGQQMISAL
                     GGQSNILSLDNCVTRLRLKLQDVSLINEDAIKEAGGIAVVKLDEHTIQVIIGTQVYSL
                     RKQMDKAMEGHLEACND"
     gene            2886..4070
                     /locus_tag="PC512_003563"
     CDS             2886..4070
                     /locus_tag="PC512_003563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PatB family C-S lyase"
                     /protein_id="HDF2443257.1"
                     /translation="MINFDKKVDRLGTYCTQWDYVEDRFGKKDLLPFTISDMDLEFPF
                     EITEVLQERLNHRVLGYSRWKHDDFRNSVTNWYIKRFNCSVDSNWIYYSPSVMYSISK
                     LIEMLSNEGDGILINTPAYNAFYDVIINNNRNIIKSHLVNRNGFYSIDFNDFEKKCKK
                     SKIFILCNPHNPTGRVWSELELVKMIGICKNNDVKIISDDIHMDIVYDNRMTPILNVA
                     KDYLDSVFICTSASKSFNIPALTGSYVIIPNEGIRNKFENITRYRDFVNSPAILAILA
                     TMVCYDDCEYWLDELLKYLKENLKYTIDYIKDNLEPLKLVMPEGCYFAWIDFSELKIS
                     GEKFQKLLMDIGEVAIMSGSVYGEEGEFYLRLNVACSREKLEDGLNRIKKTMDYIAKR
                     IL"
     gene            4088..4687
                     /locus_tag="PC512_003564"
     CDS             4088..4687
                     /locus_tag="PC512_003564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDF2443258.1"
                     /translation="MGYLKTMVDVMTTEMNAIRCLIDEAGIEYESIVSEIANCEGKVI
                     FMGVGKSAHIGKKLAATFASTGTPSFFVHATEAVHGDLGMIESKDITILISNSGNSME
                     VVNCIKYIKAIGSKTIAFTSNRNSVLAKECDYALIYPAKDEADHLNLAPTTSSTITLV
                     LGDSIACALSKSSNFGSSDFYKYHPGGSLGEKLKTANNG"
     gene            4711..5181
                     /locus_tag="PC512_003565"
     CDS             4711..5181
                     /locus_tag="PC512_003565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2443259.1"
                     /translation="MFKMFKKKSIKSPISGKVIELSKIQDGVFSQKIMGEGVAIDSTG
                     DIVYAPINGKIVVVAETKHAFVIELENGMELLIHVGLDTVNLKGEGFEVLVSMGEQVK
                     EGTPMLKINRPLIESKGISLITPVTITNHSEYNMNTCNVGNSVEGGKDTVIEFK"
BASE COUNT         1984 a          558 c         1026 g         1756 t
ORIGIN      
        1 gttattgtag tattataggg taaattgcaa aatatatacg aaagtaaaat tttaaatatt
       61 gacattaaat taaatatact atactatgta agtgtgatga gagaattttt ttagagggga
      121 tttatagtga atataaaaaa gatatttaat aacaatgtag tagtaagctc cctagaagat
      181 ggcacagaaa taattgtcac tggtgctgga gtaggattta agaaaaaagt aggcgatttg
      241 atagatgaaa atttgatttc taagaaatat tttgttcaag acgatcaaag ggacaaatac
      301 aatcaaatac ttaataagac ctctattgaa tactttaaaa tttcagaaga aattatagaa
      361 aaggctaatg aagttttaaa tactcaagtg aatgattcaa taatattagc cttaactagt
      421 cacatagaat ttgctgtcca aagagaaaaa caaggtataa aattaccaaa cttaatattg
      481 aatgagacaa aacaacttta tagggaagaa tttgaatttg gattatgggc aattgatgaa
      541 attgaaaaaa ggataggaat aaaattgcct gaagatgaag caggatatat tgctattcac
      601 ataatcaatg gtttggaaaa ttctcaaaaa gatgaaggta ttaatatact agagttttca
      661 aaacaagtta ttcagataat tgaagaagta catggattta aattggatgt aaattcatta
      721 aattatacta gacttataac tcacttaaag ttttttgttc aaaggattct ccgaaaagaa
      781 acttacaatg atagtgatat tgaagatatg tataagttag tgaataaaaa ttacaataaa
      841 cctaaagtgt gtactgaaga aattgtagca ttggtattag acagatttga atataagatt
      901 agtaaagaag aagaattata tttaatgatt cacataaata aaataacaaa cagtggttgt
      961 taggattgta actgataaag caggcaaaac ctaagtcatt gagcttaact attagattaa
     1021 gttttttgat ttaggttttt ttattagata caatcaaaat acagacagtg acttttagga
     1081 ttgtaactgg ttaagcaggc aaaacctaaa tcattgaatt taactattag gttaagtttt
     1141 ttgatttagg tttttttatt agatacaatc aaatacagac agtgactttt aggattgtaa
     1201 ctggttgagc aggcaaaacc taaatcatta aacttaatta ttaaattaag ttttttgatt
     1261 taggtttttc tataaatttg attatgtttt tagataaaaa taggagggga aaattatgaa
     1321 aaaaaataag ttaggtttat ggaacttctt ccaaatgtta ggaaaaacgt ttatgttccc
     1381 aatagcacta cttagtgttt ctgggatgat gctaggactt ggggcaggtt ttacagaccc
     1441 taagatgatt gaaatggttc catttttagg gaatgaatat gttaacttag ttttaaactt
     1501 catgttaaca ataggattat ttgcatttaa caacttggga gcattatttg caatggcaat
     1561 tccactagga ttattaaaaa aagaaaaaga gtttggtgct ttttcaggat tagtaggatt
     1621 tatagcaatg catataggta caaattttta tttaacaaga gctgatttgt tagtaccagc
     1681 agaacagatg tcaactaatg gtcaagctat gattatgggt atacaaacat ataatacaag
     1741 tgttttaggt ggtattgtag caggattaat tgtttatgca atatatgata aagttagtaa
     1801 tttaaagata ccagaatcat taggattcta cagtggacca agattagttc caattgttag
     1861 tttaatagtt atgagtatag ttggattatt aatacctatt gtttggccac catttttcaa
     1921 tgcattccaa agtttaggaa gatggatttc ttcagcagga ccattaggat atttttcata
     1981 tgcagtggca gaaagagtta caattccatt tggactaaat catcttgtaa catctgtatt
     2041 ccgttttaca ccaataggtg gaactgctgt tattgatgga gaaacgtact ttggtacatt
     2101 gaacatgttt atggcatatg tagaaaataa tcagattata cctcttgatt tagctggtaa
     2161 aatggaacaa ggtaaattga tgattcaata tggattagct ggtgctgcat tggctatcta
     2221 ccgtacagca aaaccagaaa atagaaaggc acttaaagga cttttaatat caggagtgtt
     2281 gacagttatt ataggtggta taagtgaacc aatagagttt ctattcttat tcatatcacc
     2341 agcattattt gctttccata catttatgaa tggtatagca aacatggtac ttccatactt
     2401 aggcgtgttg atgggattca caggagattt aattgcattt ataagttttg gtgtgttaag
     2461 aggaacagct acaggatggc caatagcagt attagtagca gttttatatt ttgcaatata
     2521 ctattttgta tttaagtggg caattattaa gtttaatata aagaccccag gacgtgagga
     2581 taaagaaata aaagtatctg aaggaaatgg ttcagatttc aaaaatttgt ctacatataa
     2641 aggacaacaa atgatatctg ctttaggtgg tcaatctaat atattatcac tagataattg
     2701 tgtaactaga ttgcgtttaa aactacaaga tgtatcatta ataaatgagg atgcaattaa
     2761 agaggctggt ggtatagcag ttgttaaatt agatgagcat acaatacaag taattatagg
     2821 aactcaagtg tattctttaa gaaagcagat ggataaagct atggaaggtc atttggaggc
     2881 atgtaatgat taattttgat aaaaaagtag accgattggg tacatattgt acccagtggg
     2941 actatgtaga agatagattt ggtaagaagg atttgcttcc ttttacaatt tcagatatgg
     3001 atttagagtt tccatttgaa ataacagagg tgttgcagga aaggttaaat catagagttt
     3061 tgggatacag tagatggaaa catgatgatt ttagaaattc agttacgaat tggtatatta
     3121 aaagatttaa ttgtagcgtt gatagtaact ggatatatta tagtccaagt gtaatgtatt
     3181 caattagcaa acttattgag atgttaagta atgaaggaga tggaatcctt ataaatactc
     3241 ctgcatacaa tgctttttat gatgtgataa taaataacaa tcgtaatatt ataaagtcac
     3301 atcttgtaaa taggaatgga ttctattcaa ttgattttaa tgattttgag aaaaagtgta
     3361 aaaaatctaa gatatttatt ttatgtaatc ctcacaatcc aactggtaga gtatggagtg
     3421 agttagaact tgttaagatg ataggaattt gtaagaataa tgatgtcaag ataatatcag
     3481 atgatataca catggatatt gtatatgaca atagaatgac acctatctta aatgttgcaa
     3541 aggactattt agattctgta ttcatttgta catcagcgtc taaatctttc aatataccag
     3601 cattgactgg gtcatatgtg attataccaa atgaaggtat tagaaataaa tttgaaaata
     3661 tcactagata ccgtgatttt gtaaattcgc cagcaattct agcaatatta gctacaatgg
     3721 tctgttatga tgactgcgaa tattggttag atgaactatt aaaatacctt aaagagaatc
     3781 ttaaatatac gattgattat ataaaagata atttagaacc attgaaattg gtcatgccag
     3841 aaggctgtta ctttgcttgg atagattttt ccgaacttaa aataagtggt gagaaattcc
     3901 aaaaattatt gatggatatt ggagaagttg ctattatgtc ggggtctgta tatggtgaag
     3961 aaggtgagtt ttatttaagg ttaaatgtgg catgttcaag agaaaaactt gaagatggtt
     4021 taaataggat taaaaaaact atggattata ttgcaaaaag aattttatag taggaaggga
     4081 gatagttatg ggatatttaa aaacaatggt tgatgttatg actactgaaa tgaatgccat
     4141 aagatgttta atagatgaag caggaataga atatgaaagt atagttagtg aaattgcaaa
     4201 ttgtgaaggc aaagtaattt ttatgggtgt aggaaaatct gcacatatag gtaagaaatt
     4261 ggcagctaca tttgctagta ctggtacacc tagctttttt gtacatgcaa cagaggcagt
     4321 gcatggagat ttaggaatga ttgaaagtaa ggatattaca attttaatat caaatagtgg
     4381 aaattctatg gaagtggtaa actgtataaa atatattaaa gcaataggtt ctaagacaat
     4441 tgcatttact tcaaacagaa attcagtact ggcaaaagag tgtgattatg ctttaatata
     4501 tcctgcaaag gatgaagcag accatttaaa tctagcacca acaacatcat ctacaattac
     4561 tttggtttta ggagattcta ttgcatgtgc attatctaag agtagtaatt ttggttcttc
     4621 agatttttat aagtaccatc caggaggaag tttaggtgag aagttaaaaa cagctaacaa
     4681 tggataaaag caaaaaggag agtagttttt atgttcaaaa tgtttaaaaa aaaatcaata
     4741 aaatcaccca tatcaggaaa agtaatagag ttatctaaaa tacaagatgg tgtattttct
     4801 caaaaaatta tgggagaggg tgtagctata gattctacag gagacattgt atatgctcca
     4861 atcaatggaa agatagtagt agtagcagag actaaacatg catttgtaat agaattagaa
     4921 aatgggatgg aacttcttat tcatgttggt ttagatactg taaatttaaa aggcgaaggt
     4981 tttgaggtat tggtgagtat gggagaacaa gtgaaggaag gaacaccaat gttgaaaatt
     5041 aaccgtcctt tgattgaatc aaagggtata tcacttatta ctccagttac aataactaat
     5101 cattcagagt acaatatgaa tacatgtaat gtaggcaata gtgttgaagg tgggaaagat
     5161 actgtaattg agtttaaata aagaactaaa atacaaggtt aatatttata aatacctata
     5221 aacttatgtt ttataagatt gattgtatag atttgttgta tagatttgtt gtataaaaaa
     5281 gaactcttta attataaatt aaggagttct tttttatttt gtaa
//
LOCUS       DAMJVG010000141         5178 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.146, whole genome shotgun sequence.
ACCESSION   DAMJVG010000141 DAMJVG010000000
VERSION     DAMJVG010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5178)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5178)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5178
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.146"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(285..428)
                     /locus_tag="PC512_003566"
     CDS             complement(285..428)
                     /locus_tag="PC512_003566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443260.1"
                     /translation="MSEFLLGVLASLTASFITYIISRKVKSHSGRSDFELDVKIKFNK
                     KRH"
     gene            688..876
                     /locus_tag="PC512_003567"
     CDS             688..876
                     /locus_tag="PC512_003567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443261.1"
                     /translation="MTKTILCDYCNKGINKDDNKYITFHKKSHMKTNICINCALNLID
                     KDKLNENIINNQHDYSKK"
     gene            1578..2099
                     /locus_tag="PC512_003568"
     CDS             1578..2099
                     /locus_tag="PC512_003568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HDF2443262.1"
                     /translation="MDFKIRELINDITQDIIQTYKIQIPIVNINQVVDALGGKVIEDS
                     SLSGYSDGFIRKVDDSFEIVVSPYQPDTRKNFTIAHELGHLFLHMGYGIDDELWNSQD
                     GNQYFRSGNTNKEYQSNEFAAALLMPKHEYKRIMDENTVGNKVDTSKIAEYFNVSSYA
                     ASNRGKWLGYLQW"
     gene            2075..3661
                     /locus_tag="PC512_003569"
     CDS             2075..3661
                     /locus_tag="PC512_003569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443263.1"
                     /translation="MVRIFTMVDDKEYKTQNVNNVHNSAKNENAFNLKKYKEKLQENI
                     NTDIYEKEKEPNHPEVILFFSFDIANSSLYKNINYSGWAKVLSHIIRKLQYRVYENLK
                     AQLWRVLGDEVIFIIVLKNYDEIYKYIDIIFDILTSTAKDIKSGNIFSTLEGFSESEK
                     YLMKLQNIISLKGAAWIAIVSRNPNFNALENNEQYENISAMYDLSNNYKIFEFLGNDI
                     DAGFRISKQTCPERLVLSFELAYILSRKTDILSKLHIITYKKLKGIWKDKLYPIIWYH
                     NKGKNNDIEFDDSFSFDEIEENELVREYFFNKKGESKLLIDSFMFNSVDKALDKILID
                     RNLSDKIEKIGDVISKTNPSYDKNTIDKDYIKVDLMELHCVAVCYNKSTSKILIAKRS
                     DNRNNNASKWEFGCAKASLETSIINTIKDEYEKDFNINIEPITDCTRKDDCQPIPLAI
                     YQVKKSDGLHKGIITLAEIINDYDISKFEPTSKHNELAWIGEDELEDFNENTVPDFKE
                     TLKLAFKKLNENQLQESTNM"
     gene            complement(3725..4243)
                     /locus_tag="PC512_003570"
     CDS             complement(3725..4243)
                     /locus_tag="PC512_003570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443264.1"
                     /translation="MDKKIDIAKFIVNRIDYYIEKSDNKASFLLLLNSAIIGFLFSGK
                     EKIMNHLSISNIRCLEMLFYIVILCIFVISIYFSIMVLKPRNSKIENEYKSIFYYKEI
                     ASLNNEQYKEAFENAFKDEENLINDALVQIKELSLICDKKMYNVKKSVEAFILGGIIL
                     FIYILVVVFNAI"
     gene            complement(4409..4771)
                     /locus_tag="PC512_003571"
     CDS             complement(4409..4771)
                     /locus_tag="PC512_003571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443265.1"
                     /translation="MEDLCMDALVYERFVRAAFSIKLNNLINRSEDLGGLAEADIFRA
                     ANNLHELNEIKIGTGYAIAIFNNEILESCNVSDNDSNRMIELFDRSLIATSREEILDI
                     IREYETYRGRYLTFNWKR"
     gene            complement(4852..>5178)
                     /locus_tag="PC512_003572"
     CDS             complement(4852..>5178)
                     /locus_tag="PC512_003572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF2443266.1"
                     /translation="EGIAKLIVEGVLNKNINNEGVKQMYKHTIVYDGEVDKILANVLS
                     WGYSPSKVLVCDIKDYVPGQTENLYVVGGGACEKISSITKEKFIMIKGNDRFDTLYKA
                     LDFINR"
BASE COUNT         2031 a          665 c          604 g         1878 t
ORIGIN      
        1 aaactagaga aatttagtgg cataaatata tatgaactaa gaattgtaaa atgagttata
       61 agttatatca tccagttatc aaaaacatat actctttttg tttttgtgaa agttttttag
      121 gtggctaata atatatatac ttagagataa aataaaatat atttctaata ttcatagttt
      181 tattttttct caaaatgcga tataataaag atgtaaattc gtatcaaaaa caaaaaaaga
      241 aactacaatc tattagccta gagtgaagtt tcattaacta aatattaatg tcgtttttta
      301 ttaaacttga tttttacatc aagctcaaag tcactcctgc cagagtggct ttttactttt
      361 ctggaaataa tatatgtaat aaagctagct gttaaactag ctaacactcc tagtaaaaat
      421 tcgctcattt ctccacctcc ttccttttaa gggatggaat gtagaaaatg aagctccact
      481 cttagattgt agttccacaa gattattctt gcattttaat tataacataa ttttacaatt
      541 atcaaatatc tattcttcat attttttatt tatacaatat attctatatt gcaataaaaa
      601 acattgtttt aaatatatat atacataggt atatactaaa tatgttaaac ttaattatag
      661 aaaatataaa atgaaaggaa taaaaatatg actaagacta tattatgtga ttactgtaat
      721 aaaggaataa ataaagatga taataagtat attacttttc ataagaaaag tcatatgaaa
      781 actaacattt gtattaattg tgcattaaat ttgatagata aagataaatt aaatgaaaat
      841 attataaata atcaacatga ttattcaaag aaatgaaaaa gcactctcca taatgaagaa
      901 tgctctatat aataatgttt gacttagtaa agatgtgttg gggttacata tttacttttt
      961 tattatatca tataactttg tgtatgaaaa agaatttaaa tcaattttaa ggtgtgttga
     1021 gtaatgttct tgatagttta tatgttgatg aatttcaaaa aaataagcac tcttataaaa
     1081 agagtacttt tggtatatat tcaagcattt atctaataca attatagcat gtattatgtt
     1141 ttagtatgat aattttcgtt cgttttatta ttacaacttc tactatagtt ttcatacttt
     1201 aacatcaact aaatgaattt aattaagatt actagttaat cgttttttgg ttctttcata
     1261 ttctgaaatc taaaatttta ttatttgttt attgttatta tttaacacat gttggtattt
     1321 caacgattta tcttattgtt aatattctta ttgcttccaa agtatatcta attattttta
     1381 agataattta ctaattttta ttttttcaaa catacattcg acaaaaaaca gtttttatat
     1441 ggtataatta tattgtataa tacaaaaggt taatgaaaat aattaatatt aaatgtacca
     1501 aaaaaaatag tttttgatat aatgaatatt ataataaata attatttaaa taaaatatta
     1561 tataaggatg tgattttatg gatttcaaaa tcagagagct aattaatgat ataacccaag
     1621 atattatcca aacatacaaa atccaaattc caatagtaaa tataaatcaa gttgttgatg
     1681 ctttaggagg caaggtaata gaagatagtt ctttaagtgg atactctgat ggatttatta
     1741 gaaaagttga tgattcattt gaaatagtgg tatctcctta tcaaccagat accagaaaga
     1801 attttaccat tgctcatgaa cttggacatt tatttttaca catgggttat ggcattgatg
     1861 atgaactatg gaatagtcaa gatggaaatc agtattttag aagtggcaat accaataagg
     1921 agtatcaatc caatgaattt gcagcagcct tgttgatgcc taaacatgaa tataaaagaa
     1981 ttatggatga aaacacagta ggtaataagg tcgacacttc aaaaattgca gaatacttta
     2041 atgtttcctc ttatgcagca tctaatagag ggaaatggtt aggatattta caatggtaga
     2101 tgataaagaa tataaaactc aaaatgtaaa taatgttcat aattcagcta aaaacgaaaa
     2161 cgcttttaat cttaaaaagt ataaggaaaa acttcaagaa aatattaata ctgatattta
     2221 tgaaaaagaa aaagaaccta atcatccaga agtgattttg ttcttttctt ttgatatagc
     2281 taattcatca ttatataaaa atataaatta tagcggatgg gctaaggtat tatcacatat
     2341 aattcgtaag ttacaatata gagtttatga aaaccttaaa gcacaacttt ggagagttct
     2401 tggtgatgag gtaattttca ttatcgtact aaaaaattat gatgaaattt ataaatacat
     2461 agatataatc tttgatattt taacaagcac tgctaaagat ataaaaagtg gtaatatatt
     2521 ctctacacta gaaggatttt ctgaatctga aaaatactta atgaaacttc aaaatattat
     2581 ttcattaaaa ggagcggcct ggattgctat agtatcaaga aatcctaatt ttaatgcttt
     2641 agaaaataat gaacaatatg aaaatatttc tgctatgtac gatttatcca ataattataa
     2701 aatatttgag ttcttaggaa atgatattga tgctggtttc agaatatcaa agcaaacatg
     2761 cccagaaaga cttgttctta gttttgaact agcttatata ttatcaagaa aaactgatat
     2821 tttatctaaa ttacatataa ttacatataa aaaattaaag ggtatctgga aagataaact
     2881 ataccctatc atttggtatc ataataaagg aaaaaataat gatatagaat ttgatgatag
     2941 tttttctttt gatgaaatag aagaaaatga attggttcga gaatattttt ttaataaaaa
     3001 aggagaaagt aaattactaa ttgattcttt tatgtttaat tctgtagaca aggctttgga
     3061 taaaatactt atagacagaa accttagtga taagattgaa aaaataggtg acgtaatttc
     3121 taaaacaaac cccagttatg ataaaaatac aatagataaa gactatataa aagtagattt
     3181 aatggaatta cactgtgttg cggtttgtta taataaatca acttcaaaaa tattaattgc
     3241 gaaaagaagt gataatagaa ataataatgc gagtaaatgg gaatttggtt gtgctaaggc
     3301 aagtctagaa acttcaatta taaatactat taaagatgaa tatgaaaaag attttaatat
     3361 aaacattgaa cctattactg attgcacaag aaaagatgat tgccaaccta tacctctagc
     3421 aatttatcaa gttaaaaaaa gtgatggttt acacaaaggc attataactc tcgcagaaat
     3481 aataaatgat tatgatattt ctaaatttga acccacatca aaacataatg aacttgcatg
     3541 gataggagag gatgaacttg aagattttaa tgaaaacaca gtacctgatt ttaaagaaac
     3601 tttaaaacta gcatttaaaa aattaaatga aaatcaatta caagaatcta caaatatgta
     3661 aatagtattc ttctatgatt tgattctatc ttcatagagg aatactaacc aaataaaaca
     3721 ttttctaaat agcattaaaa actactacaa gtatatatat aaacaatata ataccaccta
     3781 aaataaaagc ttctactgac ttttttacat tatacatttt cttatcacag attaaagata
     3841 attcttttat ttgaacaagt gcatcattaa tcaagttttc ttcgtcttta aatgcatttt
     3901 caaatgcttc tttgtactgt tcattattta aagatgctat ctctttataa taaaaaatag
     3961 atttatattc attttctatt ttagaattcc ttggctttaa aaccataatc gaaaaataaa
     4021 ttgaaataac aaatatacat aatataacaa tgtaaaatag catctctaaa catctgatat
     4081 tacttatact taagtgattc attatttttt ccttccctga aaataaaaaa cctataattg
     4141 cgctatttaa taatagtaaa aaactagctt tattatctga tttttcaata tagtaatcaa
     4201 ttctatttac tataaacttc gctatgtcta tttttttatc catgatttta ctacctcatt
     4261 tcattaaatt ttatattgat tcaaaatttt attttctact tattatcatt gaataaatta
     4321 ttatttggaa ataatcttat tgaaataata aaaatatgtg aaagaaagta ataactaact
     4381 ataattacta cttcctaact taaacattct atctcttcca attaaaagta agatatcgtc
     4441 ctctataagt ttcatattct cttataatat ccaatatttc ctccctagaa gttgcaatta
     4501 aacttctatc aaatagttca atcattctat tgctatcatt atcagaaaca ttacaagact
     4561 ctaatatctc attattaaat attgcaatag catacccagt acctattttt atctcattta
     4621 attcatgtaa attatttgct gctctaaaga tatcagcttc agccaatcca cctaaatctt
     4681 cgcttctatt aatcaagtta ttaagtttaa tactaaaagc tgctcttaca aatctctcat
     4741 aaaccaatgc atccatacat aaatcctcca ttatcacaat aatatattta cattatatta
     4801 caataataga gttatcacaa caaacaacca cttctagttg ataactttta tctatctatt
     4861 aataaaatcc aatgctttat aaagtgtatc aaatctatca ttacctttta tcataataaa
     4921 tttttcttta gtaatagaac ttatcttttc acatgcgcca cctcctacaa catataaatt
     4981 ttccgtctga cctggtacgt aatcttttat atcacaaact aaaactttgc ttggactata
     5041 gccccaacta agcacattcg caagtatctt atcaacttct ccatcataaa caattgtatg
     5101 tttgtacatc tgtttaactc cctcattatt tatattttta tttaatacac cttctacaat
     5161 taacttagca ataccttc
//
LOCUS       DAMJVG010000142         5106 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.147, whole genome shotgun sequence.
ACCESSION   DAMJVG010000142 DAMJVG010000000
VERSION     DAMJVG010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5106)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5106)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5106
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.147"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            53..1825
                     /locus_tag="PC512_003573"
     CDS             53..1825
                     /locus_tag="PC512_003573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2443267.1"
                     /translation="MENGKFQFFKGVRNCFNMIYLHDKRYLFISMFMAIFQGIVPSIS
                     LLVSQNIINNMQTFSKSVKEILVLLIMYLIINIIPSIFQSFYGYYRIKFNKNFEKHIE
                     TMMLEKSLTLSLKDFEDDNTYDMINRAQSQKGFNITILSENLISIIRESVSTLSLIVV
                     LSQFQLWLIIVVIVIPVLKSLYSIKLGKEQYDVSVNRTWKERKAWYIDYLLSKGYAYK
                     EIMVFRIGSKLINHYKKLKEDIISQDMNIAKKNFIATLLCTVLDSIVSAGIIGFIIIQ
                     GILKKILIGDATTYIQAVQSIKDNVESIFSLFSSVIQDLFYTDLLFKFLDYNCKEDSI
                     EHIKIFEKIGDINKIELINISYKYNHSSEYSLKNINLTLNKNDPIAILGKNGSGKTTL
                     LKILLGFYDDYEGDILINGKNLKDIEKDEYIRKVSCMFQDYIKYEATLKENVAMGDVY
                     KSNLEEKVKSKLKETKLKPSIYEEDGLETILGTWFGKKQLSMGEWQKVAISRTLMKDA
                     DMYIFDEPDSSLDSEAGNELLSLYKKTFENKIGIFITHHIQHAKKITNNIVVLENGKL
                     LESGRHDELMDKKGVYFNLFCNCK"
     gene            1847..3268
                     /gene="ccpM"
                     /locus_tag="PC512_003574"
     CDS             1847..3268
                     /gene="ccpM"
                     /locus_tag="PC512_003574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-rich peptide radical SAM maturase CcpM"
                     /protein_id="HDF2443268.1"
                     /translation="MNQKPFIHTFKAGKSYFIYDVNTDKILKVNAAVYNYLNKIEHNL
                     EKESDWNIEIEDEINTLINYGFLKNKRVSKTMHPETKYIKYHIENNLSSIILQVTQNC
                     NLRCDYCIYSGSYSNRVHTNKRMNIDVAKRSIDYLIKNSSQLNEVSVGFYGGEPLLEF
                     DLIKQIVEYVKVVGEGKEIYFNLTTNATLFNEEIIEFFVKNNITTMISLDGGKEIHDK
                     SRKFANTGEGSHDVVLKNVRYIKNKYPEYYKKNITFNTVINSENDYISIDDFISKNET
                     LKDSNFLASTLNNNYSDKEIVSSDEYILGKSYDRFLTLLNKLKFIKDESMSPLSRIER
                     ALLDDFRYEKNIEGRLELPDVWHHGGPCIPGAFRIFVTTDGEFFPCERVSESSKMGMI
                     GNLDSGVDIEKAEKLLNIGKLYEEQCSDCWAYSYCDICIAKIDDTKCNENEIKPHDCD
                     RIRHSTENNMKDYCVLKSLGYQY"
     gene            3297..4367
                     /locus_tag="PC512_003575"
     CDS             3297..4367
                     /locus_tag="PC512_003575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04066 family peptide maturation system
                     protein"
                     /protein_id="HDF2443269.1"
                     /translation="MEKVLIYPFNYNFFTILNHCNKISDIEINSLVSPSGWGLCNKEY
                     NVNNIITKVTNDFQSELKKNSLVWFVDSKENLDLEKFIIPKLKVALKEGKKILYTRDD
                     LNKISRYISHYEFKKINEWNLEKYEIRDIEGISQINTPIIFICGLYGGLDTFDVNIRI
                     GEELRKRGFSILQFGPKKESYLFKMIPIPEFMFDDSISSKAKIINFNHFIKDKEVEAK
                     PDLIIIEVPGELFPFSRKMVGNFGIRAFEISNAVINDCGILCIPSSIYDREYCEELKY
                     FIKGRHGINIDYFSIEKKVIDTYETEVKQKFSYMSLDENFFVEDIEDYEKTFFIHDNK
                     QLLELVDNIVNQLKEYAKVISI"
     gene            4383..4634
                     /locus_tag="PC512_003576"
     CDS             4383..4634
                     /locus_tag="PC512_003576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide maturation system acyl carrier-related
                     protein"
                     /protein_id="HDF2443270.1"
                     /translation="MNYTEKELLLENIFFDVTGINFNKNNNLKKELFFSPSLHIQPRE
                     LLLVFCEVIENFNIKIPEEKLLNRQFTSFDNVLKIINMV"
     gene            4685..4888
                     /locus_tag="PC512_003577"
     CDS             4685..4888
                     /locus_tag="PC512_003577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443271.1"
                     /translation="MSFGKRIEMNNIGVETRGVCTIMCPYTCKMMASSSCNCKNNDYN
                     ARGGSYNTYYNKLIHGQRTPDGM"
BASE COUNT         2071 a          454 c          826 g         1755 t
ORIGIN      
        1 tattaattaa taaaatattt tatttcaatt ttattaagta tggaggtgta ttgtggaaaa
       61 tggtaaattt caatttttta aaggtgtaag aaattgtttt aatatgattt atctacatga
      121 taaaagatat ttatttatct ctatgtttat ggcaattttt caggggattg ttccatctat
      181 ttctttgtta gtaagtcaaa atatcattaa taatatgcaa acattttcga aaagtgtaaa
      241 agaaatatta gttttgttaa ttatgtattt aatcataaat ataattcctt caatttttca
      301 aagtttttat ggatattata gaataaagtt taataaaaat tttgaaaaac atattgaaac
      361 aatgatgtta gagaaatctt taactttgag tttaaaagat tttgaggatg ataatactta
      421 tgacatgata aatagagctc aatctcaaaa aggatttaat attactatac tatctgaaaa
      481 ccttatttca ataataagag aatcagtatc tacactttct cttattgttg tattatcaca
      541 atttcaactt tggctaataa tagttgttat tgttattcct gtattgaaat cattatattc
      601 cattaaatta ggaaaggaac aatatgatgt tagtgtaaac agaacttgga aagaaagaaa
      661 ggcctggtac atagattatt tgttgtcaaa aggttatgct tacaaagaga ttatggtatt
      721 tagaattggt tctaaactta ttaatcatta taaaaaatta aaagaggata ttatatctca
      781 agatatgaat atagctaaaa agaattttat tgctacgcta ttatgtacag ttttagattc
      841 aattgtatct gcaggaatta taggatttat aataattcaa ggtattttaa agaagatttt
      901 aataggagat gcgactacat atatacaagc agttcaatct ataaaggata atgttgaatc
      961 aatattttcg ttatttagtt cagtaataca agatcttttt tatacagatt tactgtttaa
     1021 atttctagat tataactgta aagaagactc aattgaacat ataaaaatat ttgaaaaaat
     1081 aggggatata aataaaatag agttaataaa tatttcatat aaatacaatc attcatcaga
     1141 gtattcttta aaaaatatta atttaacttt aaataaaaat gatcccattg ctatactagg
     1201 aaaaaatggt tcaggtaaaa cgacactttt aaaaatatta ttaggttttt atgatgatta
     1261 tgaaggtgac atcttgataa atggaaaaaa tttaaaggat attgaaaaag atgaatacat
     1321 tagaaaagta agttgtatgt ttcaagatta tattaaatat gaggctacat taaaagaaaa
     1381 tgtcgccatg ggagatgtat ataagagtaa cttggaagaa aaagttaaaa gtaaacttaa
     1441 agaaactaaa ttgaaaccaa gtatttatga ggaagatgga ttagaaacta ttttaggaac
     1501 ctggtttggt aagaagcaac tttctatggg tgaatggcaa aaagtagcaa tatctagaac
     1561 tcttatgaaa gatgctgata tgtacatttt tgatgaacca gattcatctt tagattctga
     1621 agcgggaaat gaactccttt ctttatataa aaaaacattt gaaaataaga ttggaatatt
     1681 tataacgcac catatccaac atgcaaaaaa gataactaac aatattgtag ttcttgaaaa
     1741 tggaaagttg ttagaaagtg gaagacatga tgaacttatg gacaaaaagg gtgtttattt
     1801 taatttattt tgtaactgca aataaatatt aaagggaggt taattaatga atcaaaaacc
     1861 atttatacac acatttaaag ctggaaaatc atattttatt tatgatgtta atacggataa
     1921 gattttaaag gtaaatgctg ctgtttataa ttatctaaat aaaattgagc ataatttaga
     1981 aaaagaaagt gactggaaca tagaaataga agacgaaatt aataccttga ttaattatgg
     2041 atttctaaaa aataaaaggg taagtaaaac aatgcaccct gaaactaagt atataaaata
     2101 tcatatagaa aataatctat cctctattat tttacaagta acccaaaatt gtaatttacg
     2161 ttgtgactat tgcatttatt ctggttcata cagcaacaga gttcatacaa ataaaagaat
     2221 gaatatagat gtagcaaaaa gaagtattga ctatttgatt aagaattcta gtcaattaaa
     2281 tgaagttagt gttggctttt atggaggaga acccttactt gagtttgatt tgattaagca
     2341 gatagtagaa tatgtaaaag tagttggaga aggaaaggaa atatacttta atctaactac
     2401 aaatgcaact ttatttaatg aggaaataat agaattcttt gtaaaaaata atataacaac
     2461 tatgattagt ttagatggag gaaaagaaat tcatgataaa agtagaaaat ttgcaaatac
     2521 aggagaagga tctcatgatg ttgtattaaa aaatgtacgt tacataaaaa ataaatatcc
     2581 agaatattat aaaaagaata ttacatttaa tacagtgata aattcagaaa atgattacat
     2641 ttctatagat gattttatat ctaaaaatga gactttaaaa gattcaaact ttttagcttc
     2701 cactcttaat aataactatt ctgataaaga aatagtttca tcagatgaat atatattagg
     2761 taagagttat gatagattct tgactttact caacaaatta aaatttataa aagatgagag
     2821 tatgtcacct ttatcaagaa tagaaagagc cttattagat gattttagat atgagaaaaa
     2881 tattgaaggt agattagagt taccagatgt gtggcatcat ggtggaccat gtataccagg
     2941 agcttttaga atatttgtaa ctacagatgg agaatttttt ccatgtgaga gagtaagtga
     3001 aagttctaaa atgggtatga ttggaaattt agatagtgga gtagatatag aaaaggctga
     3061 aaaactttta aatataggaa aattatatga agagcaatgt tctgattgtt gggcctatag
     3121 ttattgtgat atatgtatag ctaagattga tgatactaaa tgtaatgaaa atgaaataaa
     3181 accacatgat tgtgacagaa ttagacattc tacagaaaat aatatgaaag attactgcgt
     3241 tttgaaatct ctaggatatc aatattaaat tttctaatga aaggaaagat gggattatgg
     3301 aaaaagtact tatatatcca tttaattata atttttttac tattttaaat cattgcaata
     3361 aaatttcaga tatagaaatt aattcactgg ttagtccttc tggctggggg ttatgcaata
     3421 aggagtataa tgttaataat attattacta aagttacaaa tgattttcaa agtgaactta
     3481 aaaagaattc tttggtatgg tttgttgatt caaaagaaaa tctagactta gaaaaattta
     3541 taattcctaa attaaaagta gctctaaaag aaggtaaaaa gatattatat acacgtgatg
     3601 atcttaataa aatatctagg tatatatctc attatgaatt caaaaagatt aatgaatgga
     3661 atttagaaaa atatgaaata agagatatag agggtatatc acagataaac acaccaataa
     3721 tatttatttg tggtctttat ggagggttag atacttttga tgtaaatata aggataggag
     3781 aagaactaag aaaaaggggg ttttcaatat tacaatttgg ccctaaaaaa gagagctatt
     3841 tatttaaaat gattcctata ccagagttta tgtttgatga ttcgataagt agtaaggcaa
     3901 agattattaa ttttaaccat tttataaaag ataaagaggt agaggcaaag ccagatttaa
     3961 taattataga agttccagga gaattattcc ctttctctag aaaaatggtt ggtaattttg
     4021 gaattagagc ttttgaaatt tctaatgcag taataaatga ttgtggtata ttatgtattc
     4081 catcaagtat atatgataga gaatattgtg aagaacttaa atattttatt aaaggaagac
     4141 atggtataaa tatagactat tttagtatag agaaaaaagt tatagataca tatgagacag
     4201 aggtgaagca aaaattttca tatatgtcat tagatgaaaa cttttttgtt gaagatatag
     4261 aagattatga aaaaacattt tttatacatg ataataaaca attactagaa ttagtggaca
     4321 atatagtgaa tcaattaaaa gagtatgcta aagtaatatc tatttagaat tggaggttaa
     4381 ttatgaatta cactgaaaag gaattactac tagagaatat attttttgat gtgactggaa
     4441 ttaattttaa taaaaataac aatttaaaaa aagaattatt tttttcaccg tctttacata
     4501 tacagccaag agaattactt ttagtatttt gcgaggtaat agaaaacttt aatataaaaa
     4561 ttccagagga aaaacttttg aataggcaat ttacgagttt tgataatgtt ctaaaaataa
     4621 tcaatatggt ataggttaat aaaggtataa agtaagtgat cttatagaaa aggggaggat
     4681 atgaatgagt tttggaaaaa gaatagaaat gaataatata ggtgttgaga caagaggtgt
     4741 ttgtactatt atgtgtcctt atacttgtaa gatgatggca tcttcatctt gtaactgcaa
     4801 gaataatgat tataatgcaa gaggaggatc atataataca tattataata aattgataca
     4861 tggccaaaga actcctgatg gaatgtaaat atttcagtaa taagtatact attaaattga
     4921 tttagcatat ttgattaaat ttatctttct tactttattt ccttttatta taaaaatatg
     4981 cagttgatta taattaagag tgtgatttta taataactgc ataaatagta tctgttatat
     5041 aaatcacctc ttcaattatt atagtggtaa atatagtgat taggggtgat ttttacaatt
     5101 taaaag
//
LOCUS       DAMJVG010000143         5053 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.148, whole genome shotgun sequence.
ACCESSION   DAMJVG010000143 DAMJVG010000000
VERSION     DAMJVG010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5053)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5053)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5053
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.148"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            24..1907
                     /locus_tag="PC512_003578"
     CDS             24..1907
                     /locus_tag="PC512_003578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HDF2443272.1"
                     /translation="MSNKNKENITLSNQIKGTIQNSLTKEAILHIPMSNYAYGYDRET
                     LHIRLRTKKNEAKRVILRIGDQYVWDKGGAGGGNLNASGVGWSGGTNIVMSKEVETEL
                     FDYWIAKCKPLNKRSRYGFIIEGQEEKLLFTEKRIIELGNENDEKELCEIGNFFGYPY
                     LNYIDIPKVPNWVKDTVWYQIFPDRFANGDPSINPEGVDKWGAIPTRDNFTGGDLQGV
                     IEHLDYLSDLGINGIYFCPITIGKTNHRYDTVDYMEVDPTLGDKETLKKLIEEAHKRN
                     IKIMLDAVFNHIGYYSKQWQDVVQNKENSRYKNWFYIKDMSKIDTPIEQIDEKNIPYE
                     TFGCEKYMPKLNTENSEVIKYLLDVGKYWIQEFDIDAWRLDVSNEVDHVFWRKFREEV
                     KKVKPDIYILGEIWHGSLPWLMGDQFDSVMNYLMSEAMKKFFCTDEINAEEFKYMIND
                     VMVSYPIQVSEVIFNLLGSHDTTRILTYANGNIDRFKLAYMFMFVQTGCPCIYYGDEI
                     GMEGELSSISEGQRKCMEWNEEKWNKDIFDFMKKIIRLRKENKELRSISNEWVLADKE
                     NGTIILKKESISIIINNSSKNIILTLPDYLANKKVKDLYEEEIVDLKEELMLEKYKFI
                     ILK"
     gene            2132..2812
                     /gene="pgmB"
                     /locus_tag="PC512_003579"
     CDS             2132..2812
                     /gene="pgmB"
                     /locus_tag="PC512_003579"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HDF2443273.1"
                     /translation="MIEAFIFDLDGVITDTAYYHYMAWRKLAHKVGIDIDTKFNESLK
                     GISRMESLDRILEFGNKKYSFSEEEKVRMAEEKNNYYVSLIDEITSNDILPGIESLLI
                     DVKSNNIKIGLSSASKNAINVLNHLGISDKFDFIADAGKCKNNKPHPEIFLMSAKGLN
                     VNPQNCIGIEDASAGIDAINSANMFSVGVGNYENLKKANLVVDSTNQLKFEYIQEKYN
                     EYIVRRII"
     gene            2809..>5053
                     /locus_tag="PC512_003580"
     CDS             2809..>5053
                     /locus_tag="PC512_003580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_097546124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HDF2443274.1"
                     /translation="MKCLFSNVDEWKIIQDKIEIKENRLAESIMSIGNGYMGMRGNYE
                     ENYSGDTHKGSYIAGVWFPDKTRVGWWKNGYPEYFGKIPNSVNYIGVRIFIDDVELDL
                     AKCKVEDFYRELDMKNGILNRRFIVNINDKKFEVRVARFLSISVKELAVIKYSIKSLN
                     SNTKIKFVPYLDSNIKNEDSNYEEKFWNGISSSSLEYKGSILSRTKENAFNTPVFTVG
                     SMMYIKTNGDVEAVSHESDYNYCENSITMDVLKNEVASIEKYVSITSTRDYKESELLR
                     KCEDILNRELSKSYDDILNEHTKLWNKRWESADVKINGDKSSQQGIRYNLFQLFSTYY
                     GEDSRLNIGPKGFTGEKYGGATYWDTEAFCVPVYLGVADKEVTRNLLEYRYNQLEQAK
                     DNAKKLGLKGALYPMVTFDGVECHNEWEITFEEIHRNGSIVYAIYNYTNYTGDYKYIK
                     EKGIDVIIEIARFWASRVHLSTKKDLYMIHGVTGPNEYENNINNNWYTNYIAKWCLDY
                     AVENILRLEKECNECIDRNNVTREEVEFWKIISNKMYLPYDEELQIIIQNDNFLDKEF
                     VEVKDLPKENFPLNQNWSWDKILRSCFIKQADVLQGIYYFGNRFTKEEKKRNFDFYEK
                     YTVHESSLSSSIYSIIASEIDNLEKAYELYSRTARLDLDNYNNDTNDGLHITSMSGSW
                     LSIVHGFAGMRTWNETLSFDPKLPKEWKNYSFNINYRDNIINVDVCSDLIKIENLKGR
                     PIKIIVYG"
BASE COUNT         2084 a          455 c          962 g         1552 t
ORIGIN      
        1 ttataaagga gggaaatttt aaaatgtcta ataaaaataa agaaaatata actttaagta
       61 atcaaatcaa aggaacaatt caaaatagtt taacaaaaga agctatatta catataccaa
      121 tgagcaatta tgcctatggt tatgatagag aaacactaca tataagactt agaactaaaa
      181 aaaatgaagc gaaaagagta attttacgaa taggagacca atatgtgtgg gataaaggag
      241 gtgcaggagg aggaaattta aatgcatctg gagttggttg gtctggtgga acaaatatag
      301 taatgagtaa agaagtagaa actgaattat ttgactattg gatagctaag tgtaagcctt
      361 taaataaacg ctcacgatat ggctttataa tagaaggtca agaggaaaaa cttttattta
      421 cagaaaaaag aataatagag ttgggaaatg aaaatgatga aaaggaatta tgtgaaatag
      481 gtaatttttt tggatatcca tatttaaatt atatagatat acctaaagtg ccaaattggg
      541 tgaaagatac tgtttggtat cagatatttc cagatagatt tgcaaatggt gacccgtcta
      601 taaacccaga aggagtagat aaatggggag ctattccaac cagagataat tttacaggtg
      661 gagatttaca aggtgtgata gaacacttag attatttgag tgatttggga ataaacggaa
      721 tttacttttg ccctattaca attggaaaaa ccaatcatag atatgatacg gtagattata
      781 tggaggtaga ccctacatta ggagataaag agactttaaa aaaactaata gaagaagcgc
      841 ataagagaaa tataaaaata atgttggatg ctgtttttaa tcatatagga tattattcta
      901 aacagtggca agatgtagtt caaaataagg aaaattctcg atataaaaac tggttttata
      961 taaaagatat gagtaaaatt gatactccaa tagaacaaat agatgaaaaa aatatacctt
     1021 atgaaacctt tgggtgtgaa aaatatatgc ctaaacttaa tacagaaaat tcagaagtaa
     1081 taaaatattt attggatgta ggcaagtact ggatacagga atttgatata gatgcgtgga
     1141 gattagatgt ttcaaatgaa gtagaccatg ttttttggag aaagtttaga gaagaagtca
     1201 aaaaagtaaa accagacatt tatatattgg gagaaatttg gcatggtagt ttaccatggc
     1261 taatgggtga ccaatttgat tcagttatga attacttgat gtcagaagcc atgaaaaaat
     1321 tcttttgtac agatgagata aacgccgaag aatttaagta tatgataaat gatgtaatgg
     1381 taagttatcc aatacaagtt agtgaagtta tttttaattt acttggaagt cacgatacta
     1441 caagaatatt gacttatgct aatggaaata ttgatagatt taaacttgca tatatgttta
     1501 tgtttgtaca aacaggatgt ccttgtatat actatggtga tgaaatcgga atggaaggag
     1561 aattaagttc aatatctgaa ggtcaaagaa aatgtatgga atggaatgaa gaaaaatgga
     1621 ataaggatat atttgatttt atgaagaaga ttattagact tcgtaaagaa aataaagaac
     1681 ttaggtctat atcaaatgaa tgggtgttag cagataagga aaatggaacg attatattga
     1741 aaaaagaatc tatttctata ataataaata attcatctaa aaatataatt ttgacgttac
     1801 cagattattt agcaaataaa aaagtaaaag atttatatga agaagaaata gttgatttaa
     1861 aagaagaact aatgttagag aaatacaagt tcattatttt aaaataatac aaaaaagtat
     1921 ttattttaga tttcatgtta aattattata cagtttaaat aagtctttat aaacgataaa
     1981 aaaatatggt ctacaagtga gtgaattgaa agtagatttt aaattaaaga ctgagttaga
     2041 gtagataatt ttataaataa tatcttaaat acaagataga aaataaattg attattagtc
     2101 taaaaatttc ttgtagaaag aggaaataag aatgattgaa gcatttatat ttgatttaga
     2161 tggtgtaatt acagatactg catattatca ctatatggct tggagaaaac tagcccataa
     2221 agttgggata gatatagaca caaaatttaa tgaatcttta aaaggcataa gtagaatgga
     2281 gtcattggac aggatattag aatttggaaa taagaaatat tcattttcag aagaagaaaa
     2341 agtgagaatg gctgaagaaa aaaataatta ctatgtatca ttgatagatg agataacttc
     2401 aaatgatatt ttgccaggta tagaaagctt gttaattgat gtaaaatcta ataatataaa
     2461 gataggtcta tcttctgcaa gtaagaatgc aataaatgta ttaaatcatt tgggtataag
     2521 tgacaaattt gattttatag ctgatgcagg aaaatgtaaa aacaataaac cacatccaga
     2581 gatatttctt atgtcagcga aagggcttaa tgtaaatcca caaaattgta tagggataga
     2641 ggatgcaagt gcaggtatag acgctataaa ctcagctaat atgttttctg ttggtgttgg
     2701 aaattatgaa aacttaaaaa aagcaaattt agttgtagat tcaacaaatc aattaaagtt
     2761 tgaatatata caagaaaagt ataatgagta tatagttagg agaattatat gaaatgttta
     2821 tttagtaatg tagatgagtg gaagattata caagataaga ttgaaatcaa agaaaataga
     2881 ttagcagagt ccataatgag tataggcaat ggatatatgg gtatgagagg aaactatgag
     2941 gaaaattata gtggagatac acacaagggg tcttatatag ctggagtatg gtttccagat
     3001 aaaactcgtg ttggttggtg gaaaaatggg tatccagaat actttggtaa aattcctaat
     3061 tcagtcaact atataggtgt aagaattttc atagatgatg tagaattaga tttagcaaaa
     3121 tgtaaagtag aagattttta tagagaatta gatatgaaaa atggtatttt aaatcgtagg
     3181 tttattgtaa atataaatga taaaaaattt gaagttaggg ttgctaggtt tttaagtata
     3241 tctgttaagg aacttgcagt aattaaatac agtataaaat cattaaattc taatactaaa
     3301 ataaaatttg taccatattt agattcaaat ataaaaaatg aagattcaaa ctatgaggaa
     3361 aagttttgga atggaatttc ttcaagttct ttagaatata aaggtagtat tctttctcga
     3421 acaaaggaga atgcatttaa tacaccagta ttcactgtgg gttcaatgat gtatattaag
     3481 acaaatggtg atgtagaagc tgtatctcat gagagtgatt ataattactg tgaaaattcg
     3541 ataacaatgg atgttttaaa aaatgaggtt gcaagtatag aaaaatatgt atctataact
     3601 tcaactagag attataagga aagtgagcta ttaagaaaat gtgaagacat tttaaataga
     3661 gaactatcta aaagttatga tgatatatta aatgaacata caaagttatg gaataaaaga
     3721 tgggaaagtg cagatgtaaa aataaatgga gataaaagta gccaacaagg tataagatat
     3781 aatttattcc aactattttc aacatattat ggagaagatt cgcgattaaa tataggtcca
     3841 aaaggattta ctggtgaaaa gtatggagga gctacttatt gggatacaga agcgttttgt
     3901 gttccagtat atctaggtgt agcagataag gaggtaacta gaaatctttt agaatatagg
     3961 tacaatcagt tagaacaggc aaaggataat gcaaaaaaac tagggcttaa aggtgcttta
     4021 tatccaatgg taacatttga tggagtagaa tgtcataatg aatgggagat aacatttgag
     4081 gaaatccacc gaaatggaag tatagtatat gcaatatata actatacaaa ttatacaggt
     4141 gactataaat atataaaaga aaaaggaata gatgtaataa tagaaatagc tagattttgg
     4201 gcaagtagag ttcatttgtc tacaaaaaaa gatttgtata tgatacatgg agtaacaggt
     4261 ccaaacgagt atgaaaacaa tatcaataat aattggtata ctaattatat agctaaatgg
     4321 tgtttagatt atgctgtaga aaatatctta cgattagaga aagagtgtaa tgaatgtatt
     4381 gacagaaata atgtgactag ggaagaagtt gagttttgga aaataatatc aaataaaatg
     4441 tatctgccgt atgatgagga actacaaata ataattcaaa atgataattt tttagataaa
     4501 gaatttgtag aagtaaagga tttaccaaaa gaaaattttc ctcttaatca aaattggtct
     4561 tgggataaga ttcttaggtc gtgttttata aaacaagcag atgtattaca gggaatttac
     4621 tattttggaa atagatttac taaagaagaa aaaaagagaa attttgactt ctatgaaaaa
     4681 tatactgtac atgaatcttc tttatcttct agtatttatt ctattattgc ctcagaaata
     4741 gataacctag aaaaggctta tgaattatat tcaagaacag ctaggcttga tttagataat
     4801 tacaataatg atacaaatga tggactgcac ataacttcaa tgtctggttc atggctttcc
     4861 attgtacatg gatttgcagg catgagaaca tggaatgaaa ctctatcttt tgaccctaag
     4921 ttgccaaaag agtggaaaaa ttattctttc aatataaatt atagagataa tattattaat
     4981 gtagatgtat gtagtgattt aattaaaata gaaaatttaa aaggtagacc aataaaaatt
     5041 attgtatatg gga
//
LOCUS       DAMJVG010000144         5005 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.149, whole genome shotgun sequence.
ACCESSION   DAMJVG010000144 DAMJVG010000000
VERSION     DAMJVG010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5005)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5005)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5005
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.149"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(46..483)
                     /locus_tag="PC512_003581"
     CDS             complement(46..483)
                     /locus_tag="PC512_003581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator
                     DNA-binding domain-containing protein"
                     /protein_id="HDF2443275.1"
                     /translation="MKIHVEQGINCDDIEITIKCSALDNNIEKIISLLSTPLLDIKGK
                     KSGEIYKLNVCDILYFETVGNKTFAYYEDDVFEIDLKIYKLSKLLANTSFSRISKSMI
                     LNMDYIKSIKVISHNRMQATLKNNEKVIINRRYIKNIKEKLNI"
     gene            complement(740..889)
                     /locus_tag="PC512_003582"
     CDS             complement(740..889)
                     /locus_tag="PC512_003582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvrJ family protein"
                     /protein_id="HDF2443276.1"
                     /translation="MDDSLQLLITNVGFPIALSMYLLVRIEGKLNTLSNSIDTLSKNI
                     LIFKK"
     gene            complement(902..1132)
                     /locus_tag="PC512_003583"
     CDS             complement(902..1132)
                     /locus_tag="PC512_003583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2922 domain-containing protein"
                     /protein_id="HDF2443277.1"
                     /translation="MEIKKKLVMSFKNVKDKQVSFSIENPKDDLTEENIKSVMDLIVS
                     KNIFSVGGFDLASVVEAKVVETNTTPYDLVIE"
     gene            complement(1950..2171)
                     /locus_tag="PC512_003584"
     CDS             complement(1950..2171)
                     /locus_tag="PC512_003584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1659 domain-containing protein"
                     /protein_id="HDF2443278.1"
                     /translation="MEVVSTKNLSSIKLKLDAGFDDKGKAVVKSKSFANVKAEALNED
                     VYAVAEAIASLQENPIVDILKLDSTSLSK"
     gene            2751..3008
                     /locus_tag="PC512_003585"
     CDS             2751..3008
                     /locus_tag="PC512_003585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDF2443279.1"
                     /translation="MKIKVEDIPVQFHAMVEIIGIDKFIEVAKLYGGTNTYIPTYKGL
                     FRYARNRDIVKQFNGVNHNELAIRYNMCVSNIKRILNENNV"
     gene            3477..4715
                     /locus_tag="PC512_003586"
     CDS             3477..4715
                     /locus_tag="PC512_003586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conserved phage C-terminal domain-containing
                     protein"
                     /protein_id="HDF2443280.1"
                     /translation="MNKGFYKLNSVVLNFDIKNDVNKIRFNHYIMRKENIQRLQGTLP
                     NGQFYMTVRRAATDLQLSISTISRLVKEFLDLGIIRLVSKGVKGNRSVYSYVSIEFNG
                     SLFDDSKYMELDCVCNDEFIDNSGIEFDCDSKDNSFNGDINVETVHCINEYLSDDDVE
                     HNYNNFHNKDTIKDKAISNISTIKKYIDESFDKNKSENSNLQQESINFNFNDTCNEID
                     KRTNNSIENNQNKRPMRLSDISLLSDKGMTNKKNYFNHNHGIQKGTKSVTKKKESLNK
                     FNKKNIQQSIINMLNKKSGKNFKIDSPISIKLINERLKEGYVLEDFYKVIEVKVAKWK
                     NTIMEMYIRPETLFSYKFESYVNENISMKSQSNVHPCKEGNSNDSSNYIHSDYTTYDG
                     SVRERKKYENVRYWNPICEI"
BASE COUNT         1924 a          495 c          700 g         1886 t
ORIGIN      
        1 ataaatttgc aattagtgat attaataaat tactttagat ttttattaaa tgtttagctt
       61 ttctttaata ttttttatat aacgacgatt tataataact ttttcgttgt tttttaaagt
      121 agcttgcatg cgattatgtg atattacttt tatacttttt atgtagtcca tatttaaaat
      181 catggattta gatattcgtg agaaggatgt attagctaat aattttgata atttatatat
      241 ttttaaatca atttcaaata catcatcttc ataataagca aatgttttat ttccaactgt
      301 ctcaaagtat aaaatatcac agacattgag tttataaatc tctcctgatt ttttaccttt
      361 tatatcaagt aacggtgtac tcaataatga aattattttt tcaatgttat tatctagagc
      421 agaacatttt atggttattt caatatcatc acaattaata ccttgttcga catgtatttt
      481 cattaatcat cacctcattt tattactgtc attagaatag cattatatct tattgagtcc
      541 aactagatgc gttctaaatt tcaaattaag catagtgaaa ttcaaaaata aaacagtgaa
      601 attcaaattt gaggtggtaa aattcaaaaa aatactatgg atatttggat aaattatcca
      661 aatatcctag tatttcacat agaatatgtc taattatttt acaaatagac ctattttatg
      721 acttacatat attgtcaaat tacttcttaa atatcaaaat atttttggat aatgtatcaa
      781 tactgtttga taaagtattt aatttaccct caattctaac caataagtac atggatagag
      841 ctataggaaa accaacattg gttattaaca gttgtaaact atcatccata aaattagccc
      901 cctattctat aactaagtca taaggagtgg tatttgtttc cacaaccttg gcttcaacaa
      961 cagaagctag gtcaaatcct ccaaccgaaa aaatattttt agatactatc aaatccatga
     1021 cagattttat attttcttca gttaaatcat cctttggatt ttctatagaa aaagaaactt
     1081 gtttatcctt tacattttta aagctcatga ctaatttttt cttaatttcc atataattac
     1141 ctccgatata ataatttata ttttaattgt ttgcttgtta atattggtat tttaattgtc
     1201 aatattaatg ttttgcttgt tagtattaat atttcaattg tcaatattaa tgttttgctt
     1261 gttagtatta atatttcaat tgtcaatatt agtgtcttgc ttgttagtat taatatttca
     1321 attgtcaata ttaatgtttt gcttgttagt atcagtgttt caattgtcaa tattagtgtt
     1381 ttgcttgtta gtattaatat ttcaattgtc aatattagtg tcttgcttgt tagtattagt
     1441 atttcaattg tcaatattag tgttttgctt gttagtatta gtatttcaat tgtcaatatt
     1501 agtgttttgc ttgttagtat tagtatttca attgtcaata ttaatgtttt gcttgttagt
     1561 attagtattt caattgtcaa tattagtgtt ttgcttgtta gtattaatat ttcaattgtc
     1621 aatattagtg ttttgcttgt tagtatcagt gtttcaattg tcaatattag tattttaatt
     1681 gttgactcta gttattgctg atatagaaaa tatttaattt atttcaatta attagattaa
     1741 agtagggtag catctaaaat agctaacatg tttaagttga aatacgttta atatattaat
     1801 ttttcaaagc attaatatat taaagttata atcaaaattg aagttataat ctgccaaatc
     1861 tatagcgtat taagtgcgtt atataactta atcttttata taaagagtta atttttttaa
     1921 tttgtaaagc agagtacgtt taaaaggtac tatttagata atgatgtact atctaatttt
     1981 aaaatatcta caatagggtt ctcttgaaga cttgctattg cttctgcaac agcataaaca
     2041 tcttcattta atgcctctgc ttttacattt gcaaatgatt tacttttaac aactgcctta
     2101 cccttatcat caaaaccagc atccaatttt agttttatac tagataaatt ttttgttgaa
     2161 acaacttcca taaaattacc tcctaaaaat ttaatttcaa agatttgtcg actttctttg
     2221 ttagctataa tactatcatc taagataata tcggagttaa acagtaattt ctaaagattt
     2281 tttgtgtaaa tttttatagg aaaaatttta cttttttgct gatgaaaaag tttacaagtt
     2341 atttgtgaag atatgttctt agtgttttga aatagtattt gtatatattc atgcttagtt
     2401 gagatagttt tgtatggatt ttcatatgtg tagagttaaa tgttaggtac taaagtttat
     2461 gttaaattaa atgttaaagc ttatgttaaa aattttatta aatttaatct gtaaataaaa
     2521 aagttaaaag tccaatatta acattttact tttaaaccat taaaatcttt attaaagcta
     2581 acaaagttat aagttatgag aaattttatt aaagttaata caaaaattaa ttttaaagct
     2641 aagaaatttt ttattagatt caataaaact aataaatata gtttagtcaa taatgtatta
     2701 aataaaaact ttgttaagtc tataaaaata tcttaaagga ggtgtaactt atgaagataa
     2761 aagtggagga tataccagtt caatttcatg caatggtaga aataattgga attgataagt
     2821 ttatagaggt tgccaagttg tatggaggaa caaatactta tatacctacg tataaggggc
     2881 tttttagata tgctagaaat agggatatag taaaacaatt taatggagtc aaccacaatg
     2941 aattggctat tagatataat atgtgtgtaa gcaatattaa gcgaatactc aatgaaaata
     3001 atgtttaaat ataataaaat aatgtttaaa cataatgaaa atagccttgt taaacgtaag
     3061 agtaaagaca aagaagatgt tttataaagt ttttttagac aaattaacta aatttactac
     3121 ttattaattt aaatacattg tatattctat aaaaaaattt gttaaatact ggagatatat
     3181 tgagaataca aagaaaatgg tcgaaaatat ttgttggcta aaaaatagat aaaatgatac
     3241 aattgcttgt ataaagggga aaaataaata aataaactat ataaataaag aaatagcaat
     3301 taatatgaca taatatattt ataaaattaa gaatataaat agatatttta aggtattagt
     3361 tgttaaatta ggaaatatta aaaaaaatat atatttatat ttaaactatt ttgttattta
     3421 tataaaaata cttatctagt tactagcaat tattagtaga aatgggggaa atagagatga
     3481 ataagggatt ttacaaatta aattcagtgg tattgaactt tgatattaag aatgatgtta
     3541 acaagataag atttaatcat tatataatga gaaaagaaaa catacaaaga cttcaaggaa
     3601 ctctgccaaa cggacaattt tatatgacag tgagaagagc tgctacagat ttacaacttt
     3661 ctatttctac tataagtagg cttgtaaaag agtttttgga tttagggata ataagattag
     3721 tgtctaaggg tgtaaaaggt aatcgttctg tatatagtta cgtaagtata gagtttaatg
     3781 gaagtttatt tgatgatagc aaatatatgg aacttgactg tgtatgtaat gatgaattta
     3841 ttgataatag tggcatagag tttgattgtg atagcaaaga taattctttt aatggagata
     3901 taaatgtaga aactgtgcat tgcattaatg agtatttgtc tgatgatgat gtagagcata
     3961 attataacaa tttccataat aaagatacta taaaggataa agccatttct aatattagca
     4021 ctatcaaaaa atatattgat gaatcttttg ataaaaataa atcagaaaat tctaacttac
     4081 aacaggagtc aataaatttc aactttaatg atacatgcaa tgaaatagat aaaagaacga
     4141 ataatagtat agaaaataat caaaataaaa ggcctatgag attgagtgac atcagtcttt
     4201 taagtgataa aggtatgaca aataaaaaga attactttaa tcataatcat ggtatacaaa
     4261 aagggactaa atctgtaaca aagaaaaaag aatccttaaa taaatttaat aaaaaaaata
     4321 tacagcaaag cattataaat atgctaaata aaaaatcagg taagaatttt aaaatcgatt
     4381 ctccaataag cataaaactt atcaatgaaa ggctaaagga aggctatgtc ttagaagatt
     4441 tctacaaagt tattgaggta aaagtggcta agtggaaaaa taccataatg gaaatgtata
     4501 taagaccaga aactttgttt agctataagt ttgaatccta tgtaaatgaa aacatatcta
     4561 tgaaaagtca aagtaatgtt cacccatgta aagaaggcaa tagtaatgat agcagtaatt
     4621 atatacattc tgattataca acatatgatg gcagtgtgcg tgagagaaaa aaatatgaga
     4681 atgtaagata ctggaatcct atatgtgaaa tttaattagt ttaagaatgt atttatgata
     4741 aataagatat taatagagaa tagtgagcta tagcaaatga tatatcaata gttggtagta
     4801 agttatatta agcaagatat tactatcagg tagtgaatta tattgaacga tatatcaata
     4861 attggtagta aattatatta agtaagatat tactatcagg tagtgaatta tattgaacga
     4921 tatattaata attggcagta aattatatta aataagatat taatatcgag taatgaatta
     4981 tattgaacga tatatcaata attgg
//
LOCUS       DAMJVG010000145         4874 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.150, whole genome shotgun sequence.
ACCESSION   DAMJVG010000145 DAMJVG010000000
VERSION     DAMJVG010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4874)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4874)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4874
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.150"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            27..830
                     /locus_tag="PC512_003587"
     CDS             27..830
                     /locus_tag="PC512_003587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443281.1"
                     /translation="MEKLRVIEMIKNNPNIIATIDNPTDEMKLLAIKENGLVLEYINN
                     PTREMQELAIDNNIRAIKFIDNPTEDMMIKAVNEGWSILDYIKNPTDKVIEMAINQAG
                     WAIKYAKNPSEELQLLAVRKNYDSIKFIKQPYESVQEEAVRISYDALRYIDSPSYNAE
                     LIAIKNNEAAISFITDLDKNKMLEFLKVNILVIKYILKKVSKDELESVLKEVLSKEDV
                     EEKYIRDFLNCSVIDRNSESIPIDKIMFIYKYGSKTAKKIAVDEKLKIM"
     gene            842..1972
                     /locus_tag="PC512_003588"
     CDS             842..1972
                     /locus_tag="PC512_003588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2443282.1"
                     /translation="MNFIDTLKSVDLILSTGEVPLIVGESGIGKTALANKLAKENDWS
                     LIVIDGNLLKEGEIGGLPTIESYVGVNSNGYKTEKKTTVYAVHNKLREIDEEISKSKT
                     VLLFIDEINRCEHTVQQELMNLILNREINGYKLHDDVKILAAMNPSSKYGSDFDYQVV
                     DMDAAQENRFVWLNMESDHTQWIKWAIDEGIERKVIEFISTFPEYLHKINEDDVRATP
                     RSYERVSKIYKVYKEKNNSIPRAVFLNVVKGNVGKVIAEEFISFIESNSEPLISYEDV
                     FLGESIDESIVERVKNESHTRLYLSAMNILKDLELNIKNDKYESNHYINRFIEFLKMY
                     PVDLMIGIMKDIRNSYIEVYKKAIENEEFVKSYFESYSLIRG"
     gene            1976..3385
                     /locus_tag="PC512_003589"
     CDS             1976..3385
                     /locus_tag="PC512_003589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443283.1"
                     /translation="MENYFDKQAKELYNKASEIINTHSMLKANRANEKFDIDIPQDFK
                     YEFFSLVDKVNLSLMEEEDNFYGYFLFQMSREIRFDISSPTGVNFKGAKYVIYFNPII
                     FLTLDIKQMETTIKHEIHHILSMHLMRAKELKGKYSTLAINMAMDIVVNKFLNNLPPY
                     ATTLEWVNLKYSLKLEPYEPFEYYVEKIQTELDLMEVDEDGEEDDSDKYGDIEIDYSP
                     ERTHDIWDESNEIDENTLREFTEKFINSSQKGKVPAYLESMISSLKNSKGELPWNLYL
                     NRIMGTVENNKKKTITRRNRRQPNRLDLRGELRSHKSEIAVALDVSGSISDEEFKQAI
                     KEVLSIVKNYNHEITIIECDNEIRRVYKVRTEKDIKDRIRIGGGTRFSPVFEYANNKK
                     INLLVYFTDGKGENKLQVIPRGYKILWVISGRGDKISLKEPYGAVKKLTKVKTNDEIL
                     EINDVRNDGYSMNSQAPIL"
     gene            3596..4105
                     /locus_tag="PC512_003590"
     CDS             3596..4105
                     /locus_tag="PC512_003590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CarD family transcriptional regulator"
                     /protein_id="HDF2443284.1"
                     /translation="MVMFLFKIDDYIMYGMTGVCKVMDITNERFTNGIKKEYYVLSPI
                     YSNNTVIKIPVDNEKVPMRKLLSKINVLSLINDIPNMDTSWIDNEKLRSEQFKKILRG
                     GKCEELIKLVRSIDNNREYVKSIGKKTHQADDNIMKEAERLLNEEFATILDISPNEVS
                     SYISSHIPQ"
BASE COUNT         2023 a          412 c          856 g         1583 t
ORIGIN      
        1 aataattata gaaagaaagg cacattatgg aaaaattgag agttattgaa atgataaaaa
       61 ataatcccaa tattatagct acaatagata atccaactga tgaaatgaaa ttgttagcta
      121 ttaaagaaaa tgggcttgta ctagaatata taaataatcc aaccagagag atgcaagaac
      181 tagcaataga taataatatt agagcaatta aatttataga taatccaaca gaagatatga
      241 tgataaaagc agtaaatgag ggatggagta tactggatta tatcaaaaac ccaactgata
      301 aagttattga aatggctata aatcaagcag gatgggcaat taaatatgct aaaaatccaa
      361 gtgaagaatt acaactgtta gcagtaagaa aaaattatga ttcgataaag tttataaaac
      421 aaccttatga aagtgtacaa gaggaggcag tgagaataag ttatgatgcc ttgagatata
      481 tagattcacc tagttataat gcagaactta tagctataaa aaataatgaa gcagctatta
      541 gctttataac tgatttagat aaaaataaaa tgttggaatt tttaaaagtg aatattttag
      601 tgattaagta cattctgaaa aaagtatcta aagatgaatt agagagtgta ttaaaagaag
      661 tattatccaa agaagatgtt gaggaaaagt atattagaga ttttttgaat tgtagtgtta
      721 tagatagaaa tagcgaaagt ataccaatag ataaaattat gtttatttat aaatatggaa
      781 gtaagacagc aaaaaaaata gctgtagatg agaaattaaa gattatgtag gagagagaaa
      841 aatgaatttt atagacacat taaaaagcgt tgacttaata ttatccactg gagaagtacc
      901 tttaatagta ggtgaaagtg gaataggaaa aacagcttta gcaaataagc ttgccaaaga
      961 aaatgattgg agtttaattg ttattgatgg aaacttactt aaagagggtg aaataggtgg
     1021 tcttccaact atagaatctt atgtaggagt taattctaat ggatataaga ctgaaaagaa
     1081 aacaacagtg tatgctgttc ataacaaatt aagagaaatt gatgaagaga tatctaaaag
     1141 taagacagtt cttttattta tagatgagat aaatcgttgt gagcatacag tacagcaaga
     1201 acttatgaat ttaattttaa atagagaaat taatggatat aaactgcatg atgatgtaaa
     1261 gattttagca gcaatgaatc catcaagtaa atatggttca gattttgatt atcaagtggt
     1321 agatatggat gcagcccaag aaaataggtt tgtttggtta aatatggaga gtgaccatac
     1381 acaatggata aaatgggcaa tagatgaggg tattgaaaga aaagttatcg agtttatttc
     1441 cacttttcca gaatatctgc ataaaataaa tgaagatgat gtaagagcca ctcctagaag
     1501 ttatgagaga gtatctaaaa tttataaagt ttataaagaa aaaaataatt ctattcctag
     1561 agcagtattt ttaaatgttg taaagggtaa tgtaggtaaa gttattgcag aagaatttat
     1621 aagttttatt gaatcaaact ctgaaccatt aatatcctat gaagatgttt ttttaggaga
     1681 atctattgat gagtctattg tagaaagagt aaaaaatgag agtcatacaa gactttatct
     1741 atcagctatg aacattctaa aagacttaga attaaatatt aagaatgata aatatgaatc
     1801 aaaccactat attaatagat ttattgaatt tttaaaaatg tatcctgtag atttaatgat
     1861 aggtattatg aaggatatta gaaacagtta tattgaagta tataaaaaag ctatagaaaa
     1921 tgaagagttt gtaaaatcat attttgaatc ttatagttta ataaggggat aatgtatgga
     1981 aaattatttt gataaacaag caaaagagct ttataataaa gcaagtgaaa ttataaatac
     2041 tcattctatg ctaaaggcaa atcgtgctaa tgagaaattt gatatagata taccacaaga
     2101 ttttaagtat gagtttttta gtcttgtaga taaagtgaat ttaagtctta tggaagaaga
     2161 agataatttt tatggatatt ttttgtttca gatgtcaaga gaaataagat ttgatataag
     2221 tagtcctaca ggtgtgaatt ttaagggagc taaatatgtt atatatttta atccaataat
     2281 ctttttaacg cttgacataa agcaaatgga gactacaatt aaacatgaaa ttcatcatat
     2341 attatctatg catttgatga gagcaaagga gttaaaagga aagtatagta cattagcaat
     2401 taatatggca atggatatag tagtaaataa atttctaaac aatttaccac catatgcaac
     2461 taccttagag tgggtaaatt taaagtattc cttaaaactt gaaccatatg aaccttttga
     2521 atattatgta gaaaagattc agactgaatt agatttgatg gaagtggatg aagatggtga
     2581 ggaagatgat agtgataaat atggagatat agaaattgat tatagccccg aaagaactca
     2641 tgatatatgg gatgaatcca atgagataga tgaaaatacc cttagagaat ttactgaaaa
     2701 atttattaac agttctcaaa aaggtaaagt tcctgcttat ttagaaagta tgatatcatc
     2761 acttaaaaat agtaagggtg aattgccatg gaatttatat cttaatagaa taatgggaac
     2821 agttgaaaat aataaaaaga agactataac aagaagaaat agaagacaac caaatcgttt
     2881 agatttgagg ggagaactta gaagtcataa gtcagaaata gcagttgcac ttgatgtaag
     2941 tggaagtatt agtgatgaag agtttaaaca agctattaaa gaagttctta gtatagtgaa
     3001 aaactataat catgaaatta caattataga atgtgataat gaaattagac gtgtatataa
     3061 agtgagaact gaaaaagata taaaagatag aattaggata ggtggaggta ctagattttc
     3121 tccagtcttt gagtatgcta ataataaaaa gattaatttg ttagtctact ttactgatgg
     3181 taaaggtgaa aataaactac aagtaatacc tagagggtat aaaattttat gggttatttc
     3241 tggaagagga gataaaattt cattaaaaga accttatgga gcagttaaaa aacttactaa
     3301 ggttaaaaca aatgatgaaa tattagaaat aaatgatgta agaaatgatg ggtactcaat
     3361 gaatagccaa gcaccaattt tataggtatt cacaggagat aagctgtatt aatttatttt
     3421 gatatgcttg ttataaaaat ctaaaaaata cattaatcaa tggttaatgt attttttaat
     3481 tttaataata taagttttac ttacatttaa gtcttaaaat gtgttaaaat ataatatata
     3541 gcagatagtt ttggcaaggt ggatttagtt gtcaaaacta ttttttttat taaggatggt
     3601 gatgtttttg tttaagattg atgattatat aatgtatggt atgacaggag tctgcaaagt
     3661 catggatata acaaatgaac gatttacaaa tggaataaaa aaagagtatt atgtattgag
     3721 tcctatttat tctaataata cagtaataaa aattcctgta gataatgaaa aagtaccaat
     3781 gagaaagtta ctttctaaaa ttaatgtgct ttcattaata aatgatattc ctaatatgga
     3841 tacatcatgg atagataatg aaaaattgag aagtgagcaa tttaaaaaaa tactcagagg
     3901 tggtaaatgt gaagagttaa taaaattagt aagaagtata gataataaca gagagtatgt
     3961 aaaatctatt ggtaaaaaaa cacatcaagc agatgataat ataatgaaag aagctgaaag
     4021 gttattaaat gaagaatttg caactatttt agatatttct cctaatgaag ttagttcata
     4081 tatttcaagt catatacctc aataaagtgt tttagtatcc tttatttaat ctattttaag
     4141 tattatttat gtatgctggt tttggtaaaa taaaatatat aattaaatta tataaaaaat
     4201 aatgatgatt gtattgaaga attacagaat agtgcggaga gcctactcct ttaggtgtga
     4261 gatggatatc acttaaagat ttaaattgtt attgtagatg tttttaatat aaaacaagat
     4321 taataagtgt attgtaagct ttaagtgaaa ttgatactat aatgagttac ttagatttta
     4381 aaatatataa tattataaaa aatcctttta ggttttgaat gaataagatg gatactatgt
     4441 tgaatagaat ccatcttatt taagttttat ttatgttgtt tatttgtaag cattattttt
     4501 gtacatgaaa acacagtgta aaaatatgct tagaattatg aagttttatt aaaaagatat
     4561 tcgacaaaat aagactaaaa atattcttaa acttataact aagataaaga ttgtatattt
     4621 atagtgtagc ctgaaaaatt gtggatgtac gaaatttatt tagtatttta ttgaaacaaa
     4681 gtagaagaag tactatagtt tatctttgaa tagattgtta ttttttagtg aaaaagttat
     4741 taggttaata cataaatata atagcttata aatagtttaa gcatgttaaa aaagtagtta
     4801 ttagagatat atagttacat tgcttataag atacttaaaa tgatagcatt cacttatatt
     4861 tagaaaatta agat
//
LOCUS       DAMJVG010000146         4849 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.151, whole genome shotgun sequence.
ACCESSION   DAMJVG010000146 DAMJVG010000000
VERSION     DAMJVG010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4849)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4849)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4849
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.151"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            <1..123
                     /locus_tag="PC512_003591"
     CDS             <1..123
                     /locus_tag="PC512_003591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF2443285.1"
                     /translation="KNLNIREWICPSCNETHDRDINASINILKEGLRLITIQNK"
     gene            250..1419
                     /locus_tag="PC512_003592"
     CDS             250..1419
                     /locus_tag="PC512_003592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HDF2443286.1"
                     /translation="MNELCKDEVVEFCNRIKGKVESVAISGVFAPVNKQQEEEVAKWV
                     REILGDIPISLSNEIGNIGILERENGAILNSALSQVGKAVSLGFEKALKDLGIDAQIY
                     FSQNDGTLMNLEYTMKYPIFTIGCGITNSIRGASFLSKVKNAIVLDVGGTTSDLGVLY
                     NGFPRESSIPVTIGGVHTNFRMPDVLTIGLAGGTCVKGEKDNIKIGPESVGYRITEDA
                     IIFGGDTLTLSDVVTKLDMAFEDRKSNVENLDKEYCNEVYKKVILKLEDAVDQMKTSQ
                     DDVELVLTGGGSIIVPEKLKGISNVIRPPHYTAANAIGAALGQISGDVEKVYSLDKMS
                     REDAIEDAKKEAVNKALKAGAKEDTIEVLNIEDVPLAYLPGNALLIKVKVVGDLI"
     gene            complement(1582..2124)
                     /locus_tag="PC512_003593"
     CDS             complement(1582..2124)
                     /locus_tag="PC512_003593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HDF2443287.1"
                     /translation="MKSYIALLRGINISGKNKIIMSELKASFVELGYSEVSTYLNSGN
                     VVFLSDVDDSKVISNTIRLMIKKQFELEIPVFIISQEELKDILNNAPNWWGDNNKEIY
                     DNLIFMFPDLSYDEFYDEVGNPKEEYEKVYHYKNAIFWSFSRKDYKKTNWWSKTASSN
                     VSDKITIRTANTVRKIVGMR"
     gene            complement(2272..2556)
                     /locus_tag="PC512_003594"
     CDS             complement(2272..2556)
                     /locus_tag="PC512_003594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDF2443288.1"
                     /translation="MAKNTKQTTVHIDETLLKEVKRIGINENKSISQIINESIIDYIL
                     VYRENEDKEKNEHDKNLNETINEFKKEEEKRMQAKSAARAIAEAKKRVLY"
     gene            complement(2619..3383)
                     /locus_tag="PC512_003595"
     CDS             complement(2619..3383)
                     /locus_tag="PC512_003595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HDF2443289.1"
                     /translation="MNNYLKFATYQLIGFTSSIPRLIKIKKNPDKFSLKEKFEFMQKQ
                     AKKSLDIVNIELNIIGKETLPKEPLLFVVNHSSMLDSFILTASVERPIGCVIADEPVW
                     RNIPIFKEWAKLLRCVYVNRKNNREGIKSIAQASQNILTGQSMAVFPEGDLTWIKEPN
                     SLVSEFRSGALKIAYKAKCPIVPLVIKNSKDTYEGYQPIGKINSVPVEVEFLEPIYDH
                     IENPRLKSSVLGENIKNKMINTIENFRKSNKTFKEF"
     gene            complement(3665..3931)
                     /locus_tag="PC512_003596"
     CDS             complement(3665..3931)
                     /locus_tag="PC512_003596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HDF2443290.1"
                     /translation="MIESRCGILCYECGYKEKVNCKGCTEIEKPFWGEQCPVKSCCED
                     KNLTHCGLCDTFPCEMLNQFAYDKEQGDDGKRISQCKKWAVLAL"
     gene            complement(3973..4782)
                     /locus_tag="PC512_003597"
     CDS             complement(3973..4782)
                     /locus_tag="PC512_003597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2443291.1"
                     /translation="MNKIINNILNTCKQYTYILPHKLLRQYIAHYTISIPDTSIKENL
                     TLIPDASGCMIFKFDKKGIESAFWGATTKTTIVKNDIENVLFRVFVEFRPGGVYYLTG
                     LSQRESTDLKISLEDFNTLFSLEVNSIFERTSTIEELVEQLDMLFLSYLLKSNIVDMT
                     IPILENARKQNSIMSVKNISQISCYSERHLNRIFNNSLGMSVKSYLRLLRINLVLQEI
                     QNNKIPFATLAQDIGYYDQSHFINDFKSICGVNPTTYIKNLSDFYNEKYKF"
BASE COUNT         1668 a          668 c          679 g         1834 t
ORIGIN      
        1 aagaacttaa atataagaga atggatttgt cctagttgta atgaaactca cgatagagat
       61 ataaatgcaa gtataaatat attaaaagaa ggattaagac taataacaat tcaaaataaa
      121 taacgtatgt aagaaccgga ggaactacgg ggatagcctg tggagaatta gtaagacata
      181 ttttagtatg caaaattctg tgaagcagga accctgtgac tttagtcatg ggaggttcag
      241 ggtagaaaga taaatgaact ttgtaaagat gaagttgtag agttttgcaa tagaataaaa
      301 ggtaaagtgg aaagtgttgc aataagtgga gtatttgctc cagtaaataa acaacaagaa
      361 gaagaagttg caaaatgggt tagagaaatt ttaggggata ttcctatatc tttatcaaat
      421 gaaataggta atataggtat attagaaaga gaaaatggag ctattttaaa ttctgcattg
      481 tctcaagtag gtaaagctgt atctttagga tttgaaaaag cacttaaaga cttaggtata
      541 gatgctcaaa tatatttcag tcaaaatgat ggaacattaa tgaatttaga gtatacaatg
      601 aaatacccaa tttttacaat tggatgtgga ataacaaatt ctataagagg agcttccttc
      661 ttatcaaaag taaaaaatgc aatagtatta gatgttggtg gaactacaag cgacttgggt
      721 gtactatata atggattccc tagagaatca tctattccag ttacaattgg aggagtacat
      781 acaaacttta gaatgccaga tgttttaact attggtcttg ctggtggtac atgtgtaaaa
      841 ggcgaaaaag ataatataaa gataggtcct gaaagtgtgg gatatagaat aactgaagat
      901 gcaataatat ttggtggaga cactctaact ttatcagatg ttgttacaaa attagatatg
      961 gcgtttgaag atagaaaaag caatgttgaa aacttagata aagagtattg taatgaggta
     1021 tataagaagg ttattttaaa attagaagat gctgtagacc aaatgaagac tagtcaagat
     1081 gatgttgaat tggttttaac tggtggagga agtataattg ttcctgaaaa actaaaaggc
     1141 ataagcaatg ttataagacc tcctcattat actgctgcaa atgctattgg tgcagcttta
     1201 ggacaaataa gtggagatgt agaaaaagta tacagtttag ataaaatgtc gagagaagat
     1261 gccatagaag atgcaaaaaa agaggctgta aataaagctc taaaagctgg tgctaaagaa
     1321 gatactatag aagtattaaa tatagaagat gttccacttg cataccttcc tggtaatgca
     1381 cttcttataa aagtaaaagt tgttggtgat ttaatttaaa gaataaatat aagtatttcc
     1441 agaattatat aaatatttct ggactcattt ttaaacttat tttatcaata aaaacagcat
     1501 aacttttgac tatattctta taagtttccg aacagccgat atatacctat tttttgaggt
     1561 ttatcggctg tttgttatct tttatcgcat tccaactatt tttcttaccg tatttgctgt
     1621 acgaattgta atcttatcac ttacatttga actggcagtc tttgaccacc aatttgtctt
     1681 tttataatct ttacgactaa aagaccaaaa gatagcattt ttataatgat atactttttc
     1741 atactcttct ttaggatttc caacctcatc ataaaactcg tcataagata agtcaggaaa
     1801 cataaaaata agattatcat atatttcttt gttgttatct ccccaccaat taggagcatt
     1861 atttagtata tcttttaact cttcttgtga aataataaaa actggtattt ccaattcaaa
     1921 ctgttttttt atcattaatc ttattgtatt tgagataacc ttgctgtcat ctacatcact
     1981 taaaaagaca acattaccac tattaaggta tgtagaaact tctgaataac caagttctac
     2041 aaagcttgct tttaattcag acataattat cttgttctta ccacttatat tgatacctct
     2101 taataatgcg atataacttt tcatataata atttcacctc taaacattca catttttcta
     2161 tgtagtacaa actggaattt gcatctttta taattctttc aaaacttctt catatgtaat
     2221 ttttttaata taaaaaaatc ggtgcttaat ttgtaccgat ttttgttttt cttagtaaag
     2281 aactcgtttt tttgcttctg ctatagctct agcagcactt tttgcttgca ttcttttttc
     2341 ttcttctttt ttaaattcat ttattgtttc atttagattc ttatcatgtt catttttttc
     2401 tttatcttcg ttttctctgt atactaatat ataatctatt attgattcgt ttattatttg
     2461 agatatactt ttattttcat taattcctat tctcttaact tccttaagta gagtctcatc
     2521 aatatgaacc gttgtttgct ttgtattttt tgccacctta atcacctctt aaaaaaaatt
     2581 ctaacattaa aatttttttt agtcaataaa ttttaatatt aaaattcttt aaatgtttta
     2641 tttgattttc taaaattttc tattgtattt atcatcttat tttttatatt ttcacctagt
     2701 acagaagact ttagtctagg attttcgata tggtcataaa ttggttctaa aaattcgact
     2761 tcgacaggaa cagagttaat tttaccaata ggttggtatc cttcataagt atcttttgaa
     2821 ttttttatta ctagtggaac aatagggcat tttgctttat atgctatctt taaagctcca
     2881 cttctaaact ccgaaaccaa tgaatttggt tctttaatcc atgttaaatc tccttctgga
     2941 aacactgcca tactttgacc tgtaagtata ttttgagagg cttgggctat actctttata
     3001 ccctcacgat tgttttttct gtttacatat acacatctta gtaattttgc ccattcttta
     3061 aatataggta tatttctcca aactggttca tctgcaatta cacatccaat tggtctttct
     3121 acacttgctg ttagtatgaa gctgtcaagc atactagaat gatttacaac aaatagaagt
     3181 ggttcttttg gcagtgtttc cttaccaatt atattaagct ctatgttcac tatatctaaa
     3241 gattttttag cttgtttttg cataaattca aatttttcct ttaagctaaa tttatcagga
     3301 ttctttttaa ttttaataag cctaggtata gaagatgtaa aacctataag ttgatatgta
     3361 gcaaatttta agtaattatt cataaaatta tctccttaaa ataaaattat ttattactgt
     3421 aaagatttta acataaaata aaatttaagt ctattttaat tcaattttgt aacatatatt
     3481 ttaaatagac agagattgag attttatatt tccaatttta gtaatcagat tttatcaata
     3541 aattactatt ctattaattt aattaaataa cctttaaatt taattataaa aactgttgca
     3601 gaaatttcta caacagttta aaaaatttac cttacaaaaa cttattttat aacaagagag
     3661 tatattataa ggctagtaca gcccattttt tgcactgaga aattcttttg ccatcatcac
     3721 cttgttcttt gtcatatgca aattgattaa gcatttcaca tggaaatgta tcacatagac
     3781 cacaatgtgt aaggttttta tcttcacaac aagattttac aggacattgt tcaccccaaa
     3841 atggtttctc aatctctgta caacctttac aattgacttt ttccttgtat ccacattcat
     3901 aacataaaat tccacatctt gattctatca ttttaagtca ctccttaaat ataaatttta
     3961 tatgattgta tatcaaaatt tatacttttc attgtaaaaa tcggacaaat tttttatata
     4021 ggttgttgga ttaacaccac aaatagattt aaaatcattt ataaaatgag attggtcgta
     4081 ataaccaata tcttgtgcta aagttgcaaa tggtatttta ttattttgta tttcttgtaa
     4141 tacaaggttt atacgaagta atctaaggta tgatttaaca ctcataccaa gagaattatt
     4201 aaaaattcta tttaaatgtc gttcactata acaactaatt tgtgaaatgt ttttaacaga
     4261 cataatagag ttttgttttc tagcattttc aagaattggt atagtcatat ctactatatt
     4321 tgatttcaat aagtatgata agaataacat atctaattgt tctactaatt cttctatagt
     4381 acttgttctt tcaaaaatgg aattaacctc taagctaaat aatgtgttaa aatcttcaag
     4441 tgaaattttt aaatctgtag attctctttg agaaagacct gtcaaataat atactccacc
     4501 tgggcgaaac tcaacgaata ctctaaaaag tacattttct atatcatttt ttacaatagt
     4561 agtttttgtt gtggctcccc agaatgcgct ttctatacct tttttgtcaa atttaaatat
     4621 catacatcca ctagcatcag gtattaatgt aagattttct ttaatacttg tatctggaat
     4681 agatattgta tagtgtgcta tatactgtct taacaattta tgtggcaaaa tatatgtata
     4741 ctgtttgcag gtatttaaaa tgttattgat tattttattc ataagtatat cctcctgata
     4801 tataaaaaat aagtatacta atttattttt tatataataa accagtttt
//
LOCUS       DAMJVG010000147         4774 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.152, whole genome shotgun sequence.
ACCESSION   DAMJVG010000147 DAMJVG010000000
VERSION     DAMJVG010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4774)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4774)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4774
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.152"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            165..1316
                     /locus_tag="PC512_003598"
     CDS             165..1316
                     /locus_tag="PC512_003598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HDF2443292.1"
                     /translation="MEIYLDNSATTKPYQEVIDKMVYALNTEYGNPSSVHRKGVEVEK
                     AIKEVRQDIAKSLGAKEKEIYFTSGGTECNNTIIRGITSLNKKRKNHIISTNIEHPSV
                     LNTLKDLEEDGFEVTYLEVGKDGKINIEDLKNAIKSTTCLVSMMHVNNEIGTIQPIGE
                     VGKYLKGLKEKIYFHVDAIQSYGKINFRLSKYNIDFMSVSAHKFHGPKGIGFMYIKEN
                     NRLKPMLTGGGQEIGIRSGTENVPGIYGLGEAVRILNKDLDVVISKVNNLKNILKNEI
                     IDNIEDIKINSPEDGVCHILNVSFRGTKGEVLLHYLEQKGIYVSTGSACSSKKKGSYV
                     LNAIGLTNEEINGTIRFSLSDMNTEEEMLEAVKVLKESICDLRSIMKRK"
     gene            1362..2537
                     /gene="thiI"
                     /locus_tag="PC512_003599"
     CDS             1362..2537
                     /gene="thiI"
                     /locus_tag="PC512_003599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HDF2443293.1"
                     /translation="MVYNILIVKYGEIGVKGKNRYIFENRLIRNIRNMLKPIGRFNVY
                     KEYGRIYVDLEDYDYEEVIEEVRKVFGIVGVCPGVRAKKDYDTLKEIALKMLEEKIEA
                     GYKTFKVESRRGDKSFGLTSQEMSMDIGGYLLSKVGDRINVDVRNPEVKIKCEYREFH
                     TMVYSDTIPGYGGLPLGTNGRAMSLLSGGIDSPVATWMVAKRGMEVEAVHFHSYPFTS
                     ERSQEKVKDLAKILAKYCGRVRLHKVNILEIQKAIGENCNEEEATILSRRFMMRIAQR
                     LSEKRHCDALITGESIGQVASQTIQGLTCTNAVVDLPVFRPLIAMDKSDIVDIAKKIG
                     TFETSILPEEDCCSVFSPRKPVTKPRLEKIEKSETALDIEKLVQDAIDKIEVEDIEF"
     gene            2693..3496
                     /locus_tag="PC512_003600"
     CDS             2693..3496
                     /locus_tag="PC512_003600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HDF2443294.1"
                     /translation="MNKKGFTLIELLVVISIIGILVIVAVPALFRNIEKSKAVTCLSN
                     RENIKTQIVIAMAEESSKGKNEVMKEVLENKDGKYFETEPKCKSGGIYSATFDDGYDG
                     ITGIESIAKVYVTCTKHPDGVEMARDIHQSMKDLIASFSQDPSIIPGASKGNDDFRKY
                     LLDNKYKNGWPTIPDEFKAKYGLSKDTLYIQPYAYSPTKSDATVVVFANNKTGGNWYT
                     SLVYDYDEGRWYKGKNGISVAGRSWDVDTDSVKSVKTEIHSKEGWGPLN"
     gene            3739..4380
                     /locus_tag="PC512_003601"
     CDS             3739..4380
                     /locus_tag="PC512_003601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase"
                     /protein_id="HDF2443295.1"
                     /translation="MNNNFQDNQTINLIQSRRSIRKFTTEQISDEQVNTLLHCAFAAP
                     SGCNKQPWHITVVQDQKLLKEISDDTLSRIHEVSNVEINKNFKLFYGAPTVLFISYDE
                     SSSWAPYDIGILTGNITTAAQALGLGSCIIGMVRGLFTPVEQGDIEGLVSVLDKEDVK
                     ESESIKMKFDTNKKYRELLDIPEGYSVPFGIAVGIPDGNLPNAREVVYKVSRV"
BASE COUNT         1914 a          454 c          924 g         1482 t
ORIGIN      
        1 ttttactata aaaatttgta ataaagtgaa aaaactagct tttcatgaaa taatatttta
       61 taatttaaga ttgtcttttt aataaagatt aacaaaaaaa atactataat tagtggtata
      121 atagttagag ttgaagattt taaataaagg taggtgtaat taagttggaa atatacttag
      181 acaatagcgc aactacaaaa ccttatcaag aagttataga taaaatggtt tatgcactta
      241 atacggaata tggaaatcct tcttctgtcc atagaaaagg tgtagaagtt gaaaaagcta
      301 taaaagaagt aagacaagat atagctaaat ctctaggagc gaaagaaaag gagatttatt
      361 ttacatcagg tggtacagag tgtaataata ctataataag aggtattact agtttaaata
      421 aaaaaagaaa aaatcacata atatctacta acatagaaca tccttctgtt ttaaatacat
      481 taaaagattt agaagaagat ggttttgaag taacttattt agaggtcgga aaagatggga
      541 aaataaatat agaggattta aaaaatgcga taaagtcaac tacatgctta gtaagcatga
      601 tgcatgttaa caatgaaata ggaactatac agccaatagg tgaagttgga aagtatttga
      661 agggtttaaa agaaaaaatt tatttccatg ttgatgctat tcagtcatat ggaaaaatta
      721 attttagact atctaaatac aatatagatt ttatgagtgt aagtgcacat aaatttcatg
      781 gtccaaaggg aattggattt atgtatataa aagaaaataa tcgccttaag cctatgttaa
      841 caggtggtgg tcaggaaatt ggaattaggt cgggaacaga aaatgtacct ggaatatatg
      901 gtcttggaga agctgttaga atactaaaca aagatttaga tgttgttatt tcgaaagtaa
      961 ataacttaaa aaatatatta aaaaatgaaa taattgataa tatagaagat ataaaaatta
     1021 attctccaga agatggagta tgtcatatat taaatgtatc atttagaggg acaaaaggag
     1081 aagttttact tcattactta gagcaaaagg gtatttatgt atcaactggc tctgcatgtt
     1141 cttctaaaaa gaaaggtagt tacgtattaa atgctatagg tcttacaaat gaagaaataa
     1201 atggaacaat aagatttagt ttatctgata tgaatacaga agaagaaatg ttagaagctg
     1261 tgaaagtttt gaaagaatca atttgtgact taaggtcaat aatgaaaaga aaataaagaa
     1321 tactgtatag atagtgataa taaattagtt taagaggtga aatggtgtat aatatattaa
     1381 tagtaaagta tggagaaatt ggagtaaaag gaaagaatag atatatattt gagaataggc
     1441 ttataagaaa cataagaaat atgttaaaac caattggaag atttaatgta tataaagagt
     1501 atggaagaat atatgttgat ttagaagact atgattatga agaagtaatt gaagaagtta
     1561 gaaaagtatt tgggatagtg ggtgtgtgcc ctggagtaag agctaaaaaa gattatgata
     1621 cattaaaaga aatagcttta aaaatgttag aagaaaaaat agaggctgga tataaaactt
     1681 ttaaggtaga gtcaagaaga ggagataagt ctttcgggtt gacttctcaa gaaatgagta
     1741 tggatatagg tggatactta ttatcaaagg taggagatag gattaatgtt gatgtaagaa
     1801 atccagaagt taaaataaag tgcgaataca gagaatttca tactatggtc tatagtgata
     1861 ctatacctgg atatggtgga ttgccacttg gaacgaatgg tagagctatg tctcttttat
     1921 caggaggtat agatagccca gtagctacat ggatggttgc aaaaagaggt atggaagtag
     1981 aggcagttca ctttcatagt tatccattta caagtgaaag gtcacaggaa aaagttaagg
     2041 atttagctaa aatactggca aaatactgtg gtagagtaag gcttcataaa gttaatatct
     2101 tagaaataca aaaagcaatt ggcgagaatt gtaatgaaga agaagctact attctttcaa
     2161 gaagatttat gatgaggata gcacagagac tttctgaaaa aagacattgt gatgctttaa
     2221 ttacaggtga aagtattggg caggttgcat ctcaaactat acaaggactt acttgtacta
     2281 atgccgttgt agacttacca gtgtttagac cacttatagc aatggataaa tcagatatag
     2341 ttgatatagc caaaaaaata gggacttttg aaacatctat attgcctgaa gaagattgtt
     2401 gtagtgtatt ttctcctaga aagcccgtca ctaaacctag attagagaaa atagaaaaat
     2461 ctgaaacagc acttgacatt gaaaaattag tacaggatgc tattgacaaa atagaggtag
     2521 aggatattga gttttagcat acaagttatt taattactaa attgaatatt gagtatatta
     2581 gtagttctgt aagtatatta gtagttctgt tgaaaggatt tatgtagaca atttattaat
     2641 atgtagtatt taaaaataag tactataatt ttatttaatg ggaatgatta ttatgaataa
     2701 aaagggtttt acactaattg aattgttagt agttatatct ataataggca ttttagttat
     2761 agtagctgtt ccagcattgt ttagaaatat agaaaaaagt aaagcagtta catgtctttc
     2821 taatagagaa aatataaaga ctcaaattgt tattgcaatg gctgaggaat caagtaaagg
     2881 caagaatgaa gtcatgaaag aggtattaga aaacaaagat ggtaagtact ttgaaacaga
     2941 accaaagtgt aagtcaggtg gaatatattc agcaacgttt gatgatggtt atgatggaat
     3001 aactggaata gaaagcattg caaaagtgta tgttacttgt acaaaacatc cagatggtgt
     3061 tgaaatggct agggatatac atcaaagtat gaaagatttg attgcatcat tttcacaaga
     3121 cccttctata ataccaggag cctcaaaggg taatgatgat tttagaaaat atttattaga
     3181 caataaatat aaaaatgggt ggcctacaat tccagatgaa tttaaggcaa aatatggatt
     3241 aagtaaggat acactatata tacaaccata tgcatatagt cctactaaat ctgatgctac
     3301 tgtagttgta tttgcaaata ataagactgg gggtaattgg tatacttccc tagtttacga
     3361 ttatgatgaa ggtagatggt ataaaggtaa aaatggtatt tctgttgcag gtaggtcatg
     3421 ggatgttgac acagatagtg ttaagtctgt aaaaacagag attcattcta aagagggatg
     3481 gggtccttta aattaatata tcatgtttta ttaatctggt attgattaaa ctatagaaaa
     3541 gagcagtttc tatagatgac gaataccaga ttttcattta tatatataat tgagatatat
     3601 taaaagtgtt tatattttta agtcttcaca tacaagctaa aaataattat aataatattg
     3661 taaagaaatt taattataag attaattttc tgaagattta gtatttgtac taagaaatac
     3721 ataaaaaggg gaatagatat gaataataat tttcaagaca accaaacaat aaatttaata
     3781 caaagtcgta gaagtatacg aaaatttacg acagaacaaa ttagtgatga gcaagtaaac
     3841 acattattac actgtgcatt tgcagcacct tcaggatgta ataaacagcc ttggcacata
     3901 actgttgtgc aagaccagaa acttttaaaa gagattagtg atgatacttt atctaggatt
     3961 catgaggtga gtaatgttga gataaataaa aactttaagt tattttatgg tgctccaacc
     4021 gttttattta tttcttatga tgaaagtagt tcatgggctc catatgatat aggaatactt
     4081 acagggaata taacaacagc tgcacaagca ctagggcttg gaagttgtat aataggaatg
     4141 gttagaggtt tatttacacc tgttgaacaa ggggatattg aaggtcttgt gagtgtattg
     4201 gataaagaag atgtaaaaga atcagagtca ataaagatga agtttgatac aaataaaaaa
     4261 tacagagaac tacttgatat accagaaggg tattctgtac catttggtat tgctgtaggt
     4321 attccagatg gaaatttacc aaatgctaga gaggtagttt ataaagtttc cagagtttag
     4381 gataaagtat tgcaagaacc aatcagttac ttgaagaatt aaaccagtaa tatacaaata
     4441 aattgatgga agaggaagct atttaaaaag tagtttagat ttttcgttgt aaaataatta
     4501 aataaagaat aaggtgataa gtattttatt tattatctta ttctttttta tttttgtttt
     4561 gtagaatgat aaaaataagg attaagtgta ataaaataga aaacaagtat gttaatttta
     4621 agtatatgct ttaaaattta tccaagttaa aaatttaaga tatcttttca gtataatgga
     4681 aaaaatgtca aaatattgaa atagggaaaa aatagtgata taataagaaa aaatagagaa
     4741 aaaaagtaac ccttagttat aaaagggttc tttt
//
LOCUS       DAMJVG010000148         4691 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.153, whole genome shotgun sequence.
ACCESSION   DAMJVG010000148 DAMJVG010000000
VERSION     DAMJVG010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4691)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4691)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4691
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.153"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            100..237
                     /locus_tag="PC512_003602"
     CDS             100..237
                     /locus_tag="PC512_003602"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix domain-containing protein"
                     /protein_id="HDF2443296.1"
                     /translation="MKHEQTTLRIPEDLYKALIDLSKEIGMPIASIVIIACWLYISKI
                     N"
     gene            complement(223..534)
                     /locus_tag="PC512_003603"
     CDS             complement(223..534)
                     /locus_tag="PC512_003603"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443297.1"
                     /translation="MTTITVRIYTPLNENLEKISYQTGILKSSLILYAINDIIRNSKV
                     NELQSISYKSDDTVRSTLRIPGVLKELLEKTAKENNLSVNSLINNAVHSFCISHWLIY
                     L"
     gene            655..825
                     /locus_tag="PC512_003604"
     CDS             655..825
                     /locus_tag="PC512_003604"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443298.1"
                     /translation="MEKVRMTVRLVPKLNQYVQNIAKECGKSKNSIIVDACWEFIEKI
                     KKENKFNVESEE"
     gene            828..1619
                     /locus_tag="PC512_003605"
     CDS             828..1619
                     /locus_tag="PC512_003605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HDF2443299.1"
                     /translation="MNNLQIFEKLEFGQIRMVEVDKKPYFVATDIAKCLGYANTSKAI
                     NDHCRWVTKSYIPHPQNENKILEVNTIPESDMYRLIVNSKLPNAEKFESWVFDEVLPT
                     IRKTGGYIHTTEDMTDDEIMARALQVAQKTIEKKSREIEEKDKVIQLQQPKVLFADAV
                     ASSDDSILVGELAKLLKQNGIDTGEKRLFAWLRDNGYLIKRKGEDYNTPTQKSVDLKI
                     METKKRAIYNPDGSTKITKTPKVTGKGQIYFINKLKLVNQLSMLS"
     gene            1679..1876
                     /locus_tag="PC512_003606"
     CDS             1679..1876
                     /locus_tag="PC512_003606"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443300.1"
                     /translation="MKISFESVVNNVNNETELILSKEELQIAKRILNTLNENEQSILS
                     SKDILDFCKEALKYNLVPTFV"
     gene            complement(1863..2063)
                     /locus_tag="PC512_003607"
     CDS             complement(1863..2063)
                     /locus_tag="PC512_003607"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443301.1"
                     /translation="MKVGDIMQFSKDILHTLTLEILKEKYDFKSSSEEELLKHYHEIF
                     LKLSEVNNSFSKGDGLSVFKQM"
     gene            2116..2313
                     /locus_tag="PC512_003608"
     CDS             2116..2313
                     /locus_tag="PC512_003608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2443302.1"
                     /translation="MAINDNINKILKDRDLKAWKLAKEIGVDSGNLYAILRGENKNPT
                     IDTLIKIADYLDITLDELVGR"
     gene            2343..2786
                     /locus_tag="PC512_003609"
     CDS             2343..2786
                     /locus_tag="PC512_003609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2443303.1"
                     /translation="MSKLGNISNFNLDKQEDKSFNDLDNISICFSEGIRKVVEMNLNN
                     YKNKISKYLNETSKIELLEPKELTIVISKGYPDYLMSVEEASKRLKIDKVFGYELIKN
                     GLLKSVDIGATKVSSYELDDFITRNQGKNIKEMLREMKEIREGVI"
     gene            2787..2933
                     /locus_tag="PC512_003610"
     CDS             2787..2933
                     /locus_tag="PC512_003610"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443304.1"
                     /translation="MNVRVLIAYVQFCNDKQIKASFEGLRKYNRDIELVNLYLPSKLK
                     IKGD"
     gene            2936..3253
                     /locus_tag="PC512_003611"
     CDS             2936..3253
                     /locus_tag="PC512_003611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443305.1"
                     /translation="MKSLTIVRNAVEQQLNRANLEINKNEELYTKLRKKEKRDVLDEI
                     ELSNALREKSVNERLKIFAESLLKIIDTQIEIKEYEESEDYKIFELISEEIERDRPID
                     IQI"
     gene            3331..3840
                     /locus_tag="PC512_003612"
     CDS             3331..3840
                     /locus_tag="PC512_003612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HDF2443306.1"
                     /translation="MSTLYELTTDLLEIEEGLTETTGNEAEKLEEIKEIIKQEIQNKN
                     TRIVSVILNIDSDINSIDSEIKRLQELKKVKKNTLDRLKSNIKDCMELLGTKKVETVL
                     GNISIRKSAGSLVIEDEEKIPAIYKTVEQVVKVDKNTIKDFIKKGHEVEGCRIEYGTT
                     LTIPKAKKE"
     gene            3850..4434
                     /locus_tag="PC512_003613"
     CDS             3850..4434
                     /locus_tag="PC512_003613"
                     /inference="COORDINATES: protein motif:HMM:NF016302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ERF family protein"
                     /protein_id="HDF2443307.1"
                     /translation="MEINNIYIKLMDVRVKFSKLNLKKSGENKFANFKYFELADFLPQ
                     ATGLLEEAKLCPIVTFTNEYATLTLINGENPSEQIVFTSPMRDLQLKGSNELQALGGI
                     ETYQTRYLYIQLLNITESDTFDATSGKNEAKSNSNNRILTDKQLSRLYAIASNANVDK
                     ESLKEKVFKRFGKEIKDLTKQEYDTICNAYENKQ"
     gene            4449..>4691
                     /locus_tag="PC512_003614"
     CDS             4449..>4691
                     /locus_tag="PC512_003614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HDF2443308.1"
                     /translation="MGIIRVSKDKDNPYVVLNKTCLEDVKLSWQAKGLHSYLISKPDH
                     WKIYVNDLYKRSKNGRDATANILRELIENGYITRTPC"
BASE COUNT         2061 a          499 c          821 g         1310 t
ORIGIN      
        1 attaataaat ttaaaagtag caaacaatta tcaatgttaa gttaaaacat aacagtacct
       61 tgaaaactaa atacagaata ttcaaaagag gtgattgaat tgaaacacga gcaaacaacg
      121 cttcgtatac cagaagactt gtacaaagcg ttgatagatt taagtaagga aatcggaatg
      181 cctattgcat ctattgtaat aattgcgtgt tggttgtata tatcaaagat aaattaacca
      241 atgagatatg caaaatgaat gcacagcatt atttattaga gaattgactg ataaattatt
      301 ttctttagct gttttctcta gcaactcttt taggacacca ggaatcctaa gagtagaacg
      361 aacagtatca tcacttttat acgagattga ttgaagttca ttaacttttg aatttctaat
      421 aatatcatta atagcgtata gaataagcga agatttgaga atgcctgttt gataagaaat
      481 tttttctaaa ttttcattta atggtgtata tattcttaca gtaatagtag tcattttgac
      541 acctccctaa tgacattata caaaaaatat ttaaaaaagt cttgacacta aaatagtgtc
      601 ataatataat gattatagac agtgaataag tgtcataagg agggaggaat aagaatggaa
      661 aaagtaagaa tgacagtaag gctcgtccca aaattaaatc aatatgtaca gaatatagcc
      721 aaagaatgtg gaaaaagtaa aaattctatt attgtggatg catgttggga gtttattgag
      781 aaaataaaaa aagaaaataa attcaatgta gaaagcgagg aataaatatg aataatctac
      841 agatatttga aaaattggaa tttggtcaaa taagaatggt tgaggttgat aagaaaccat
      901 attttgttgc aacagatata gctaaatgtt taggatatgc aaacacaagt aaagcaataa
      961 atgaccattg taggtgggta acaaaaagtt acatacctca tccgcaaaat gaaaataaga
     1021 tattagaagt aaatacaata cctgaaagtg atatgtatag attgattgta aatagtaaac
     1081 taccaaatgc agaaaaattt gaaagttggg tatttgatga agttttacca acaatacgta
     1141 aaactggagg atatatacat acaacagaag atatgacaga cgacgaaata atggcaagag
     1201 cattacaagt agctcaaaag acaatagaaa agaaaagcag agagatagaa gaaaaagata
     1261 aggtaattca gttacagcaa ccaaaagtat tgtttgctga tgcagtagca tcctcggatg
     1321 attctatatt agttggagaa cttgcaaaac tacttaagca aaatggcatt gatacaggcg
     1381 agaaaagatt atttgcatgg cttagagata atggttactt aataaaacgt aagggtgaag
     1441 attacaatac accaactcaa aagagtgttg acttaaaaat aatggaaact aaaaaaagag
     1501 caatatataa ccctgacgga agtacaaaga ttactaaaac accaaaagta acaggcaaag
     1561 gtcaaatata ctttatcaac aaattgaaat tagtaaatca attatcaatg ttaagttaaa
     1621 atataacagc actttgaaaa ctaaatacag aatattttaa aaaggagtgt gtaattaaat
     1681 gaaaatttca tttgaaagtg tagtgaacaa tgtaaataat gaaacggaat taatattatc
     1741 aaaagaagag ttacaaatag ctaaaaggat acttaataca ttgaatgaaa atgaacaaag
     1801 tatcctttcc tcaaaagata ttttagattt ttgcaaagaa gctcttaaat ataatttagt
     1861 acctacattt gtttaaagac actgaggcca tcgcctttag aaaaactatt attgacttct
     1921 gaaagtttca aaaagatttc atggtaatgt tttaaaagtt cctcttcaga agaactttta
     1981 aaatcatatt tttccttaag aatttctaaa gtaagagtat gtaatatatc tttactgaac
     2041 tgcataatat caccaacttt cataaaaaga tataggatat atcctacaaa tatagtatat
     2101 caaaggagga aaataatggc aattaatgac aacataaata aaattttaaa agatagagat
     2161 ttaaaagcat ggaaattagc aaaagaaata ggtgtagatt cagggaattt atatgcaatt
     2221 ttaagaggag aaaataaaaa tccaactata gatacattaa taaaaatagc cgactattta
     2281 gacattacat tagatgaact agttggaaga taaaaattaa atacagaata ttttgaaaag
     2341 gagtgagtaa attgggcaat atatctaatt tcaatttaga taaacaagaa gataaaagtt
     2401 ttaatgacct agataatata tcaatttgtt tttcagaagg tatccgtaaa gttgtagaaa
     2461 tgaatttaaa caactataaa aataaaatct caaagtactt aaatgaaact tcgaaaatag
     2521 aattattaga accaaaagaa ctaacaattg ttataagtaa aggttatccc gattatctta
     2581 tgtctgttga agaagcaagt aaaagattga aaatagataa agtatttgga tatgagttaa
     2641 taaaaaatgg gcttttgaag tcagttgata taggggcaac taaagtttct agttatgaat
     2701 tagatgattt tataactaga aatcaaggaa aaaacatcaa agaaatgctt agagaaatga
     2761 aagaaattag agagggggtg atttagttga atgtaagagt actaatagct tatgtacagt
     2821 tttgcaatga taagcaaata aaagcaagtt ttgaaggtct tagaaaatac aacagagata
     2881 tagagttagt taacttgtat ttaccaagta aattaaaaat taagggggat taatcatgaa
     2941 aagtttaact atagtaagaa atgcagtaga gcaacaacta aatagagcta atttagaaat
     3001 aaataaaaat gaggaacttt atacaaaact tagaaaaaaa gaaaaaagag atgtattaga
     3061 tgaaatagag ttaagtaatg ctttaagaga aaaaagtgta aatgaaagat taaaaatatt
     3121 tgctgagtca ttactaaaaa ttatagatac acaaattgaa ataaaagaat atgaagaaag
     3181 cgaggattac aagatatttg aattaatttc agaagaaatt gaaagagata gacctataga
     3241 tattcagata tagaaaagag ccattaggag tggctcgatt ccaaaataat ataaaatata
     3301 agctaattat agcacaaacg gagggaaatt atgagtactt tatatgaatt aactacagat
     3361 ttattagaaa tagaagaagg tttaacagaa acaacaggaa atgaagctga aaaactagag
     3421 gaaataaaag aaataataaa acaagagata caaaataaaa acactagaat agtgtcagta
     3481 atattaaaca ttgacagtga tataaactct atagattcag agattaagag gttacaagag
     3541 ttaaagaagg ttaagaagaa tactcttgat agattaaaaa gcaatataaa agactgtatg
     3601 gaattacttg ggactaaaaa agtagaaaca gttttaggaa atataagtat aagaaagtca
     3661 gcaggtagct tagtcataga agatgaagaa aagatacctg ctatatataa aacagtagag
     3721 caagttgtaa aagtagataa gaacactatt aaagatttta ttaaaaaagg tcatgaggtt
     3781 gaaggttgca ggattgaata tggaactaca ctaacaattc caaaagctaa aaaagagtag
     3841 gtgaggacca tggaaattaa taatatttac attaaattga tggatgtaag agttaaattt
     3901 agtaagttga atctaaagaa aagtggagaa aataagttcg ctaacttcaa gtattttgag
     3961 ttagcagact ttctaccaca agcaactgga ttacttgaag aagctaagct atgccctata
     4021 gtgaccttta caaatgaata tgcaactcta acattaatta atggggaaaa cccatcagaa
     4081 cagattgtat ttacttctcc catgagagat ttacaactta aaggttctaa tgaattacaa
     4141 gcactaggag gtatagaaac ctatcaaact agatatttgt acattcagtt actcaacata
     4201 actgaaagtg acacttttga cgcaactagt ggcaaaaatg aagctaaaag taattctaac
     4261 aatagaattt taacagataa acaattaagt aggttatatg caatagcaag taatgcaaat
     4321 gttgataaag aaagtttgaa agaaaaagta tttaaaagat ttggaaaaga gataaaagat
     4381 ttaacaaaac aagagtatga cactatttgt aatgcttatg aaaataagca ataagggcag
     4441 gtgatattgt ggggattata agagtaagca aagacaaaga taatccatat gtagttttaa
     4501 ataaaacttg tttggaagat gtgaaattaa gctggcaagc aaaaggttta cattcatatc
     4561 tgattagtaa gcccgaccac tggaaaatct atgttaatga tttatataaa agaagtaaaa
     4621 atgggaggga tgctacagca aatattttaa gggagctcat agaaaatgga tatataacaa
     4681 gaacaccttg t
//
LOCUS       DAMJVG010000149         4530 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.154, whole genome shotgun sequence.
ACCESSION   DAMJVG010000149 DAMJVG010000000
VERSION     DAMJVG010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4530)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4530)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4530
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.154"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            206..1681
                     /locus_tag="PC512_003615"
     CDS             206..1681
                     /locus_tag="PC512_003615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HDF2443309.1"
                     /translation="MDSEFANAVELSYECAPLLESLKEYSEKDIACFDVPGHVKNRGV
                     AILNKYLGESLMKMDINSSPTMDNVSAPNGIIKNAQDLLAQAYMADEAFFITNGTTQA
                     IHAMILSVIKPGEKVLLPRNIHKSVINALILCGGIPIFIQPEFDEKLGISLNITLEKV
                     RTEIEKDCNIKALFFLNPTYYGVCADLESIIELCHKNNVLVLVDEAHGAHFPFHLDLP
                     PSAISLGADMVAVSIHKTGGALTQSSALLLNRDNVSFEKVLQSINMLQSTSASYLLMA
                     SIDGARVNLVENGEKQLSKALNLSRYAKSKLNKIDGIKVLSTEILKQKGVKFIDETKL
                     CINVKELNLTGFEVYDLLYKNFSIQVELGDSYNILALVSIGTNKSDIDRLVKALSIIA
                     KIYRKESTLNEFNMVQINPIIKLNPREAFYAPKESVEINSCIDRICGESIMAYPPGIP
                     IIAPGELITEEIMEYIIFLKNSNAYLTDVQDKNLDRILVIK"
     gene            1768..2181
                     /gene="speD"
                     /locus_tag="PC512_003616"
     CDS             1768..2181
                     /gene="speD"
                     /locus_tag="PC512_003616"
                     /EC_number="4.1.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylmethionine decarboxylase"
                     /protein_id="HDF2443310.1"
                     /translation="MKFETLGRHILVEYYNCDENVLKDPRLIENFMNDSALNAKATIV
                     DSVFHHFNPWGVSGAVIIAESHLTIHTWPEYGYAAADFFTCGDIDPWKSFELLEQLLK
                     SERSESTEIPRGLTTKIKKYSKKDLGKITHKPEAV"
     gene            2211..3062
                     /gene="speE"
                     /locus_tag="PC512_003617"
     CDS             2211..3062
                     /gene="speE"
                     /locus_tag="PC512_003617"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HDF2443311.1"
                     /translation="MELWYTEEWTENVRFSIKVNKHLFEGKSQFQRIDVFDSDEFGKF
                     LTIDGLMMVTYKDEFIYHEMITHVPMATNLNIKKVLVIGGGDGGTVRELSRYPQIEKI
                     DMVEIDKMVVDVSKEYMDICSCKLDDKRVSLYFEDGVNFVKCAHDKSYDLIIVDSTDP
                     IGPGEGLFSTDFYKDCYRILTDDGILVNQSESPYFDFNAKEMKRANKKLKQIFPISEV
                     YQAHIPTYPSGHWLFGFASKKLNPVKNQDRNGWEKLSLKTKYYNSDIHLGSFMLPQYV
                     KEMLDEE"
     gene            3052..3930
                     /gene="speB"
                     /locus_tag="PC512_003618"
     CDS             3052..3930
                     /gene="speB"
                     /locus_tag="PC512_003618"
                     /EC_number="3.5.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatinase"
                     /protein_id="HDF2443312.1"
                     /translation="MKNNFYHMNTFMSMNKNYEESNLIVFGVGFDGTTSNRPGARFAS
                     SSMRKEFYGLETYSPFLDLDLEDYNICDYGDLEISVGSTEQVLKEIYQETYKIVRDSK
                     VPFMIGGEHLVTLPAFKAVHEKYNDIYVIHFDAHTDLREEYNNSKNSHATVIKRIWDI
                     VGDNKIFQFGIRSGTKEEFKFATEEKHTYMEIGGIDTFENIVNMLNGKNIYLTIDLDV
                     LDASVFPGTGTPEPGGVNYREFQEIFKIIKNSNINIVGCDIVELSPDYDTTGVSTVIA
                     CKILRELCLIISDKIK"
     gene            complement(4096..4296)
                     /locus_tag="PC512_003619"
     CDS             complement(4096..4296)
                     /locus_tag="PC512_003619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000809131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDF2443313.1"
                     /translation="MKNGIVKWFNNEKGFGFISVEGEDDVFVHFSAIQNDGYKTLEEG
                     EKVSFDITQGNRGPQAENVNRI"
BASE COUNT         1801 a          500 c          774 g         1455 t
ORIGIN      
        1 aaacaacaaa aaattaaaaa gtttataaat attgatatag ctaatgtata tgtttttgag
       61 taacttcaaa aaaacacttg taaaaatgct gggatgttaa tataataaat atcatgagtt
      121 taataaaagt aaaaataaaa aatagaaata ataaataata aatattaaaa atatttgaat
      181 atagagagga gatgaatttg aaatcatgga tagcgagttt gcaaatgcag ttgaattaag
      241 ctatgagtgt gctccattat tagagtcgtt aaaggaatac tcagagaaag atatagcttg
      301 ttttgatgtg cctggacatg taaaaaatag aggtgtagct atattaaata aatatctagg
      361 tgaaagtctc atgaaaatgg atataaattc atcaccaact atggataatg tatctgcgcc
      421 aaatgggatt ataaaaaatg cacaagattt gttagcacaa gcatatatgg ctgatgaggc
      481 attctttata acgaatggca caactcaagc aatacatgca atgattttga gtgttataaa
      541 accaggtgaa aaagtattac ttccaagaaa catacataaa tcagtaataa atgcgttaat
      601 actttgtgga ggaataccaa tatttataca accagaattt gatgaaaaac taggtataag
      661 tttaaatatt actcttgaaa aagttagaac agagatagaa aaagattgta atataaaagc
      721 attatttttc cttaatccaa cttactatgg agtttgtgca gaccttgaga gtattataga
      781 actatgccat aaaaataatg ttttagtgtt agttgatgaa gctcatggtg cacattttcc
      841 atttcattta gatttacctc cttctgcaat aagtttggga gctgacatgg tagctgtaag
      901 tatacataaa actggaggag cattgacaca atcttcagca ctcttattga atagagataa
      961 tgtaagtttt gaaaaggttc ttcaatcaat caatatgcta caatcaacat cagcatctta
     1021 tttgcttatg gcaagtatag atggtgctag agttaatcta gttgagaatg gtgaaaagca
     1081 attgtcaaaa gcattaaatc tatctaggta tgcaaaatct aaattgaaca aaattgatgg
     1141 aataaaagtt ttatctacag aaatattgaa acaaaaaggt gttaaattta tagatgaaac
     1201 aaaattgtgt ataaatgtaa aagaattaaa tttgactgga tttgaagtat acgatttatt
     1261 atataaaaat ttttcaattc aagtagaatt gggagattca tataatatac tggcacttgt
     1321 gtccattgga acaaataaat cagatataga tagattagta aaggcacttt ctataattgc
     1381 aaagatttat agaaaagaat caacattaaa tgaatttaat atggttcaaa taaatccaat
     1441 tattaaactt aatccaagag aagcttttta tgcaccaaag gaaagtgtag aaatcaattc
     1501 atgtatagat agaatttgtg gagaatcaat aatggcatat ccaccaggta taccgattat
     1561 tgctccagga gaattgataa cagaagaaat tatggagtat attattttct taaaaaatag
     1621 caatgcatat cttacagatg tacaagataa aaacttagat agaatactag taataaaata
     1681 aattacttta ttttgcaagg gcaagtgttt gttaagtaga gtttatcaaa tagaacttat
     1741 taaaagtata aaggagttgg ggttgaaatg aaatttgaaa cactaggaag acatatacta
     1801 gtagaatact ataattgtga tgaaaacgta cttaaagacc cacgtcttat agaaaatttt
     1861 atgaatgatt cagcattaaa tgcaaaagcg acaattgtgg attctgtatt ccaccatttt
     1921 aatccttggg gggtttcagg agctgttata attgctgaat ctcatttgac aatacataca
     1981 tggcctgaat atggttatgc agcagcagat ttttttactt gtggtgatat agacccatgg
     2041 aaaagttttg aattattaga gcaactttta aagtctgaaa gaagcgagtc tacagaaatt
     2101 ccaagaggct taactacaaa aattaaaaaa tattcaaaaa aagatttagg taagattact
     2161 cataaaccag aagcagtata aaacatacaa gagaaagtga ggattattat atggaacttt
     2221 ggtatacaga agaatggaca gaaaatgtaa gattttctat aaaagtaaat aaacatctat
     2281 ttgaaggaaa gtctcaattt caaaggatag atgtgtttga tagtgatgaa tttggaaaat
     2341 ttctaacaat agatggatta atgatggtaa catataaaga tgaatttata taccatgaga
     2401 tgataactca tgttcctatg gctacaaatt taaacataaa gaaagtatta gtcataggtg
     2461 gaggtgatgg aggtacagta agagaattaa gccgttatcc tcaaatagaa aagattgaca
     2521 tggttgaaat agataaaatg gttgtagatg tatctaaaga gtatatggat atatgctcat
     2581 gtaaattaga tgataaaaga gtgagtttat attttgaaga tggtgttaat tttgttaagt
     2641 gtgcacatga taaatcatat gacctgataa tagtagattc aactgaccca ataggaccag
     2701 gtgaagggct tttctcaact gatttttata aggattgtta tagaatactg actgatgatg
     2761 gaattttagt aaatcaaagt gaaagtccgt attttgactt taatgctaaa gagatgaaaa
     2821 gagctaataa aaagttaaaa cagatatttc caatatcaga agtttatcaa gcacatatac
     2881 caacatatcc atctggtcac tggttgtttg gatttgcttc aaaaaaactt aatccagtaa
     2941 aaaatcaaga tagaaatgga tgggagaaat taagtttaaa aactaaatat tataatagtg
     3001 atatacattt aggttcgttt atgttacctc aatacgtgaa ggagatgctg gatgaagaat
     3061 aatttctatc atatgaacac ttttatgagt atgaacaaaa attatgaaga atctaatctt
     3121 atagtatttg gtgttggatt tgatggaact acttctaaca gacctggggc tagatttgca
     3181 agtagctcta tgagaaaaga attttacggt cttgagacat atagtccttt tttagatttg
     3241 gatttagagg attataatat atgtgattat ggagatttag aaattagtgt tggaagtaca
     3301 gaacaagtct taaaagaaat ctatcaagag acatataaga ttgttagaga ttcaaaggta
     3361 ccctttatga ttggaggaga gcatttagtt acattaccag cctttaaagc agtacatgaa
     3421 aagtataatg atatatatgt aattcatttt gatgcccata ctgatttgag ggaagaatat
     3481 aataatagta aaaattctca tgcaacagta attaaaagaa tatgggatat tgtaggtgat
     3541 aataaaatat ttcaatttgg tataaggtct gggacaaaag aagaatttaa atttgctaca
     3601 gaagaaaaac acacatacat ggaaatagga ggaatagata cgtttgaaaa tatagttaat
     3661 atgctaaatg gaaagaatat ttatctaact atagatttag atgtattgga tgcatctgtg
     3721 tttccaggaa caggtacacc agaacctggt ggtgtaaatt atagagagtt tcaagagatt
     3781 tttaagatta taaaaaactc taatataaat atagttggtt gtgacattgt agagttaagc
     3841 cctgattacg atacaacagg tgtatcgaca gttatagctt gtaaaatctt aagagagtta
     3901 tgcttaataa tatctgataa aattaaatag agtattttat ataaatagta tatattataa
     3961 tataagaagt tattttaagt ttgacgcttt tctaaagtaa cttcttattt ttgtaattaa
     4021 aaataaatat aataaacaac aaaaaagagc cctcgatagc tccttttcta aaatatatat
     4081 atttaaatta aataattata ttctatttac gttttcagct tgaggtcctc tattaccttg
     4141 agttatatca aagctaacct tttcgccttc ttctaaagtt ttgtatccat cattttgtat
     4201 agctgagaaa tgtacgaaaa catcatcttc tccctctaca gatatgaatc caaatccttt
     4261 ttcattgtta aaccatttta ctattccgtt tttcattata agaaaacctc cgcattatta
     4321 aaaaatacaa actaaaaaaa taagtctgtt ctattaatat aacataaatt ttaaataaaa
     4381 gcaaataaaa tttttaaaaa aattaattac ttttagaatt taataaaaat tgttaaatta
     4441 tacagtgaga agtattgtaa aatttgacga aaatgtaaat gtagataata aatttaatat
     4501 caaaaaatgt aacaaaaagg tatgtaagta
//
LOCUS       DAMJVG010000150         4516 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.155, whole genome shotgun sequence.
ACCESSION   DAMJVG010000150 DAMJVG010000000
VERSION     DAMJVG010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4516)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4516)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4516
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.155"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(944..1354)
                     /locus_tag="PC512_003620"
     CDS             complement(944..1354)
                     /locus_tag="PC512_003620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443314.1"
                     /translation="MKIKKSLISAMMVSAMVLGGTGAVFANGNDSSNIALPKLESLIK
                     SGITDPTELEKYGVEHYTYEEYAKHIQELKDYAKDPNAVKDVSQKDLEETIKKMEQEL
                     EKIKTEGLKIMKPITIENEDGSQISIAYNYAAID"
     gene            complement(1570..2952)
                     /locus_tag="PC512_003621"
     CDS             complement(1570..2952)
                     /locus_tag="PC512_003621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HDF2443315.1"
                     /translation="MFIKLLEMSFTSGVLLLIVIFIRACLFKKLPKKVFVLLWLIVLF
                     KLLIPVSLNSGFSIYSIIESTFDVELGNTSTENYTLKKASDSTGKNNSDEFEIMSNIE
                     NIMMLEMLGILSFIVTIMFSILLCFRYFKIINLFKTSIHIKNHEFIKKWMCKNSRFRR
                     FIVCISEFTRTPLTSGILKPRIILPKQMNYANNQTLDFVLTHEMVHINSFDNLLKLFM
                     LVALVVHWFNPLVWVMFFLLNKDIEFSCDEKVMSILGEEYRADYATTLISLAEENNPF
                     SMTICSGFGKTKIEKRIVNIMKFKKSTYVTFLVSTVLVCGTGLVFATENKEINEVESF
                     GLTKNEQSDKIGFSISSKSTDLYSPKVESDILVSKAKSDGETHFSTAKVSVIEFREHE
                     ESSMSKVTNSENSEETYVNKSSNGKDVLYTDSGEVSIEQSGYNDNRFVISRKGNLLAV
                     NKEQYRTWIE"
     gene            complement(2963..3322)
                     /locus_tag="PC512_003622"
     CDS             complement(2963..3322)
                     /locus_tag="PC512_003622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2443316.1"
                     /translation="MEIKLFDSELKVMEVLWERGESKAGELVKILKEETGWNRNTTYT
                     VIKKLVSKGAIERIEPNFVCKALISKEEVQKQETETLINKMFGGSSEKFLSAFINKEN
                     LSSDEITKLKQIVEKLK"
     gene            complement(3527..4306)
                     /locus_tag="PC512_003623"
     CDS             complement(3527..4306)
                     /locus_tag="PC512_003623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HDF2443317.1"
                     /translation="MVSRQELKRVSKAQLSGNWGICAISMAVYIALIVLISIVGLPFE
                     PLTTIVVAVIAFCVSAGFTCMFLKITKDEKVKIGDIFVSGRIYLRSFGFYLFESIIVY
                     IYSFIITIIGAFLSFGVLLTSGAIEYLSSDNVGIGTVISTGITLVLIILVLMLPVYIL
                     LLYVSQATFLICEDKDNMGVFKSMGASLDMMKGNVLKLFVLNFSFIGWYILSIATLGI
                     GLLWLIPYVGVTNCNFYRQLVKENPDVEDILLDKEKSYTMY"
BASE COUNT         1571 a          767 c          401 g         1777 t
ORIGIN      
        1 ccatcatcca tatatttatt ttacgattac tctttcaccc taacccttta actatctatt
       61 ttttcttact attcttatcc acatcatcca tatatttatt ttacgattac tctttcactc
      121 taacccttta actatctatt ttttctgata ttcttatcca ccatcaccca tatatttatt
      181 ttacaattac tcttttaccc taacccttta actatctatt tttttctggt attcttatct
      241 actattatct gtatatttat tttatgatta ctcttttaac ctacccccta tactttatag
      301 taatatgttt ttaacctttt tcattattcc caatatgctt tataactaca aatactctcc
      361 ccccttaaaa ataataataa aattaatcaa taaatttata atcatattat tactctatgt
      421 attaagcaat tactatgcca ataaactttg atttttttaa acaaatctta aaaatcctaa
      481 aatgctaatt ttctttaact tttaatgaat ctaatagata acatttaatt ttcgttatat
      541 ttttcagaat atttctatta ttatttttaa gaaaaaaaaa taatgttaac atttcttaac
      601 atacattaaa aaatgttaac attataaatt gggtttaata cttttacttt gactcgattt
      661 acttttattc tacttcttac tttattttta acttagactt tattttttta ttacttattt
      721 gagtcttatt tattttatta tcactccata tgttcaatta catttgtcta aattctttga
      781 tacttttatt acataatttt aacaagctta agtgttattt gggtagtgca gttgataatt
      841 atttaaataa tcatcaactg catgtttata tcattacagt agcttaatgt atttaatcat
      901 acttacttag gattttgaaa tatcttagag attatattta acattagtca attgctgcat
      961 aattgtaagc aattgaaatt tgagacccat cttcattttc tatagtgata ggcttcataa
     1021 tttttaatcc ttcagttttt atcttttcta attcttgttc cattttctta attgtttcct
     1081 caaggtcttt ttgacttaca tctttgactg cattagggtc tttagcatag tcttttaatt
     1141 cttgaatatg tttagcatac tcttcataag tataatgctc aacaccatac ttttccaatt
     1201 cagtagggtc agttattcct gattttatta gagattcaag tttaggtaaa gcaatattag
     1261 atgaatcatt tccatttgca aatactgctc cagttcctcc tagtaccatt gcagatacca
     1321 tcattgcact tataagggat ttttttattt tcataaccaa tcttcctttc ttagagattt
     1381 atttgggtag tgtagtttga aatgactatt gcaatagtta tcaaccacat ccttagacta
     1441 tcacagtagt catgtttatg tcaagccttt ttaaaaaact tttcaataaa aaatactatc
     1501 tcaaaacaaa attaattatt ttgagatagt attttaattc taaatctttt atattactaa
     1561 gatttatggt tactctatcc atgttctata ttgttcttta ttaactgcta acaaattccc
     1621 ttttcttgat atgacaaagc gattatcatt atagccactt tgctcaattg aaacttctcc
     1681 tgaatcagta taaagtacat ccttaccatt actagattta tttacatacg tttcttcgct
     1741 attctcagaa ttagttactt tgctcataga tgattcttca tgctctctaa attcaattac
     1801 agatactttt gccgtactaa aatgagtctc tccatcactt ttagctttac taacaagaat
     1861 atcagattct actttgggag aatataaatc agttgattta ctacttattg aaaatccaat
     1921 tttatcactt tgttcatttt ttgttaaacc aaaagattca acctcattaa tctctttatt
     1981 ttctgttgca aaaacaagac ctgtcccaca aactaataca gttgaaacta aaaaagtaac
     2041 ataagttgat tttttaaatt tcataatatt aactattctc ttttctattt ttgtctttcc
     2101 aaatccacta catattgtca ttgaaaatgg attattctcc tctgctagac ttattagtgt
     2161 ggttgcataa tcagccctat attcttcacc aagtatactc ataacctttt catcacaact
     2221 aaattctatg tctttattta gtaaaaaaaa catcacccaa actaagggat taaaccaatg
     2281 gacaacaaga gctacaagca taaataactt taacagatta tcaaagctat taatatgaac
     2341 catttcatga gttaaaacaa agtctaaagt ttgattatta gcataattca tttgctttgg
     2401 caaaataatt cgtggtttta aaataccaga tgtaagtggt gtcctagtaa attcagatat
     2461 gcaaacaata aatcttctaa aacggctatt cttacacatc cattttttaa tgaactcatg
     2521 attttttata tgaattgaag ttttaaaaag attaattatt ttaaaatatc taaagcataa
     2581 aagtatgcta aacataatag taactataaa agacaaaatg cccaacattt ccaacatcat
     2641 aatattttca atattagaca ttatttcaaa ttcgtcagaa ttgtttttac ctgtagagtc
     2701 actagctttc ttaagagtat aattttctgt tgatgtatta cccaattcca catcaaaagt
     2761 cgattcaatt atactataaa tactaaaacc agaatttaaa cttactggta ttagaagttt
     2821 aaataaaaca atcaaccaca ataatacaaa taccttttta ggtaattttt taaataaaca
     2881 tgctcttata aaaataacta ttaaaagtaa tactccagaa gtaaaactca tttctaacaa
     2941 tttaatgaac ataaatctta cctcacttta atttttcaac aatttgttta agttttgtaa
     3001 tctcatcact tgaaagattt tctttattaa taaaagctga aagaaatttt tctgaagacc
     3061 ctccaaacat tttattaatt aaagtttctg tttcctgttt ttgtacttcc tctttgctta
     3121 ttaaagcttt acaaacaaaa ttcggctcaa ttctctctat tgcacctttt gacactaatt
     3181 tttttataac ggtatacgta gtgtttctat tccatcctgt ttcttctttt aaaattttta
     3241 ctaactctcc agccttgctt tctcctctct cccatagaac ttccattact ttaagttctg
     3301 aatcaaataa ttttatctcc atataaaatc gctcctcaaa tatagttatc acaatagtca
     3361 ttactataat aaaaaactat catagtagtc tatactatgt caatcattta ttttttaata
     3421 ataaaaactg tctttttaaa aaattcttat aaaagacagt tttatcaatg ttatacttta
     3481 atctttaatt aaagccatat tttatttaaa tatataacta tatatcttag tacatagtat
     3541 aagatttttc tttatctaat agtatatcct ctacatctgg gttttctttt actaattgtc
     3601 tataaaaatt acaattagta acacctacat atggaattag ccatagtaga cctattccaa
     3661 gagtagctat tgaaagtata taccatccta taaaactaaa gtttagtaca aataatttaa
     3721 gtacatttcc tttcatcata tctaaactag cacccattga tttaaataca cccatattat
     3781 ccttgtcttc acaaattaag aaagtagctt gagaaacata taatagcaat atataaaccg
     3841 gtaacataag aacaagtatt ataagaacta gagttattcc agtagaaata acagtcccta
     3901 ttccaacatt atcacttgat aaatattcaa ttgctccact agtaagtaaa actccaaatg
     3961 ataaaaacgc tcctataatt gtgattataa aagaataaat ataaacaata attgattcaa
     4021 ataaataaaa accaaaactt cttaaataaa ttctcccact tacaaagata tctcctatct
     4081 tgactttttc atctttagta attttcaaga acatacatgt aaatcctgct gaaacgcaaa
     4141 aagctattac agccactaca atagtagtca atggttcaaa aggtaatcct acaattgata
     4201 ttaatactat caatgcaata tatactgcca tagaaattgc acatatcccc cagtttccag
     4261 ataactgagc tttagatact cgttttaatt cttgccttga taccataaaa aacacccctt
     4321 tcattttata aaaaaacttt taaaaatata aataatcttt taacgtataa tattaatata
     4381 tcatattttc gactatataa gatacaatta ttcaccatgt tttatcaaga tataccataa
     4441 ttgtattact agttttatat agtcaacatt accaaataca tcaaataaat ttgattaatt
     4501 attcaacaag taataa
//
LOCUS       DAMJVG010000151         4424 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.156, whole genome shotgun sequence.
ACCESSION   DAMJVG010000151 DAMJVG010000000
VERSION     DAMJVG010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4424
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.156"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            13..681
                     /locus_tag="PC512_003624"
     CDS             13..681
                     /locus_tag="PC512_003624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443318.1"
                     /translation="MENITSYFTTILCVFICLSSVFIFTQLARVFINKKKINQKIKSR
                     NGFRYDRDFIEARREEIHIKDNNNNKNKSNNKKLKEEKVFKYDNGDLYKGEFVDGKKN
                     GFGIYIFSGKEKYEGLWKDDKMHGIGKYTYRDGSIYTGEFKYGLKNGLGKLTYPNNDI
                     YKGYFLDNKKNGKGVLYKNDGNKQAGIWEDDEQCKSLDFKDLNNNKINNVYQNRLNNN
                     KLKV"
     gene            840..1346
                     /locus_tag="PC512_003625"
     CDS             840..1346
                     /locus_tag="PC512_003625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HDF2443319.1"
                     /translation="MKEYVVVDLETTGLDPYKGCEIIEIGITEIKNEQIVKNYSRLIK
                     PKGIISSFITELTHISNEMVENEEPLELVLPRFRKYIGDRTIIAHNAKFDLKFLNYYL
                     RMLDLEPINNYICTVELLKKCKSYKGKNKKLETACAYYNIENINAHRADSDTLATAKL
                     FLKIKDEY"
     gene            1474..2490
                     /locus_tag="PC512_003626"
     CDS             1474..2490
                     /locus_tag="PC512_003626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HDF2443320.1"
                     /translation="MGYYNDNDNNKIRRKKISNNKDSNKKSKHSYTSANKKNKSPNTS
                     SSKRMSEKVDSQNLIKRDRDSFTRDNVRPLNTDYNQRERRRVEYKQREKKLKSKKRKK
                     QKRIRIVRALLSIMLVALIIFSVAGAIFTVSAIKGSPEVTKKLIRSKYISSEVVSIKQ
                     MPNDLKHAIVSIEDERFYKHKGVDVISLVRSVLNNVFTDTTQGASTIDMQVSKNLLTS
                     NDKTMKRKIRDMYNAKQMNKIMTKDEILEAYLNNMYLGKNAYGAAKGAEVYFGKKVSE
                     LNLAECAMLAGMTNNPARYIDHGEAKKRQVIVLYKMHQLGYITDKEYRIAKADDTPFK
                     SEID"
     gene            2844..3548
                     /locus_tag="PC512_003627"
     CDS             2844..3548
                     /locus_tag="PC512_003627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B3/4 domain-containing protein"
                     /protein_id="HDF2443321.1"
                     /translation="MKKFVIEDAFWNLFPSAKIGVVICNDIDNSIKDEDYKKIILKGE
                     EEALKYLEDSEFSNNQVIKVWREAFKKFKTKKGARSSIEALLKRVHNGNNIGTINPLV
                     DIYNFISLKYALPCGGEDIDKFIGDIRLTRAIGNEEFIPLGTDENSFPYEGEIIYKDD
                     GGAICRCWNWREAVRTMLTEDTNNAFLCIELVDESRFKEFENALNELAKIVQEKLGGN
                     CKISILDIDNKEVSVD"
     gene            3843..4322
                     /locus_tag="PC512_003628"
     CDS             3843..4322
                     /locus_tag="PC512_003628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HDF2443322.1"
                     /translation="MSNKLIKNLLSGILQILFFLLGLVIVVGGFKSFMYLCFSGEATL
                     QGTIYGILMFILGVSYFIIIKSLIEVLGSSEYSLFVKENVKRFRIIGYLLLLNSLIEF
                     ISTFGTTGKGMRFLDLGFGFYFTVPVFVYFITSLMSFVIADGFVKAIKIKEDNDLTI"
BASE COUNT         1853 a          375 c          761 g         1435 t
ORIGIN      
        1 gggtgatttt ttatggaaaa tataactagt tattttacaa caatactatg tgtatttata
       61 tgcttatcat ctgtatttat atttactcaa ctagctagag tatttattaa taagaagaag
      121 attaatcaaa aaattaaatc aagaaacgga tttaggtatg atagagattt tattgaagcc
      181 agaagagaag aaatacatat aaaggataac aataataata aaaataagag taacaataag
      241 aaattaaagg aagaaaaagt atttaaatac gataatggtg atttatataa aggtgagttt
      301 gttgatggaa agaaaaatgg atttggaata tatatttttt caggtaagga aaagtatgaa
      361 ggattatgga aagatgacaa gatgcatgga ataggaaaat atacttatag agatggttca
      421 atatatacag gtgaatttaa atacggatta aaaaatggtt tgggaaaatt aacatatccc
      481 aataatgaca tttataaggg atatttttta gataataaga aaaatggtaa gggtgtatta
      541 tataaaaatg atggaaataa acaagcagga atatgggaag atgatgaaca atgtaaaagt
      601 ttagatttta aagatttaaa taataataaa ataaataatg tttatcaaaa tagattaaat
      661 aacaataaat taaaagttta attattctaa taaaaaaatc tttatttatg atggaatata
      721 ggatatatct atgttgtaat ttgtaaaatc ttcctatatc atataaaatt aagtattgat
      781 tagtctatta cataaatata gaatataaat atatccattt aataataagg agaagagata
      841 tgaaagagta tgtagttgtg gatttagaaa ctacaggatt agatccatat aaaggttgtg
      901 aaataataga aataggaata acagaaataa aaaatgaaca aattgtaaaa aactattcaa
      961 ggttgataaa acctaagggg ataatttctt catttataac agaattgaca catataagta
     1021 atgaaatggt agaaaatgaa gaaccactag aattagtttt acctagattt agaaaataca
     1081 taggtgatag aactataatt gcacacaatg cgaaatttga tttaaaattt ttaaattact
     1141 atcttagaat gttagattta gaaccaataa acaattatat atgtacagta gagttattaa
     1201 aaaaatgtaa aagttataaa ggaaaaaaca agaaacttga aacagcttgt gcttattaca
     1261 acatagagaa tataaatgct catagagctg acagtgatac attagcaact gcaaaactat
     1321 ttttgaaaat aaaagatgaa tattaattat aaatatagag aaaattagtg aaaatatcct
     1381 ttataaaatt gacccttaag cttacaattt tgttctttga tttattttgt agaacaatgt
     1441 ataatgtacc ttatatgaag aagggagact aaaatgggtt attacaatga taatgataat
     1501 aataaaataa gacgtaaaaa aattagtaac aacaaagata gtaataaaaa atctaaacat
     1561 tcttatactt cggcaaataa aaaaaataaa agtcctaata caagttccag taaaagaatg
     1621 agtgaaaaag tagattcaca gaatcttata aaaagagata gagatagttt tacaagagat
     1681 aatgtaagac ctttaaatac agattacaat caaagagaaa gaagaagagt cgagtataaa
     1741 caaagagaga aaaaattaaa aagtaaaaaa agaaaaaaac aaaaaaggat tagaatagtt
     1801 agggcattat tatctattat gttagttgca ctaattatat tttcagtggc aggtgcaata
     1861 tttacagttt cagctataaa agggtcacca gaagttacta aaaagttaat taggtctaaa
     1921 tatataagta gtgaggttgt aagtataaaa caaatgccaa atgatttaaa acatgcaata
     1981 gtttccatag aagatgagag attttataag cataaaggag tagatgttat ttctctagtt
     2041 aggtcagtat taaacaatgt gtttacagat acaacacaag gtgcaagtac tatagatatg
     2101 caagtttcaa aaaacctgct tactagtaat gataaaacta tgaagcggaa aataagggat
     2161 atgtataatg ctaagcagat gaataagatt atgactaagg atgaaattct tgaagcatat
     2221 ttaaataata tgtatctagg taaaaatgca tatggagctg caaagggagc tgaagtctac
     2281 tttggtaaaa aagttagtga attaaattta gctgagtgtg ctatgttagc tggtatgaca
     2341 aataatcctg caaggtatat tgaccatgga gaggctaaga agagacaagt gattgtactg
     2401 tataagatgc atcagcttgg ttatataact gataaggagt atagaatagc aaaagctgat
     2461 gacactccat ttaaatcaga aattgattaa aattgtaaga atatagtatt ttcaatagtt
     2521 taaacaaaca aaaatgtaat aaaaaaggtg atttgccacc catttgccac cataattata
     2581 atctaatggc aaattgtttt aatgtacaaa ctagataata gaatattgtc ttaaatgcta
     2641 tattatgcta aaatttaatt gtattttgta aattaaaaaa cttataattt agttttctag
     2701 ggttccgcat tttataatgg tcaggtccaa gagaaaacgc gcaattgttg tgtacacgga
     2761 aggataaaag cctgggagat atttaagaat atttctatag gcttttttat ttttacatat
     2821 tttaaatttg aggaggtttt ctaatgaaaa aatttgttat tgaggatgca ttttggaatc
     2881 tatttcctag tgcaaaaatt ggagttgtta tttgtaatga tatagataac tctataaaag
     2941 atgaagacta taagaaaata attttgaagg gagaagaaga agcattaaaa tacttggagg
     3001 actcagaatt tagcaacaac caagtgatta aagtatggag agaagcattt aaaaaattta
     3061 aaacgaaaaa aggagcaagg tcttctattg aagcattatt aaaaagagtt cataatggaa
     3121 ataatatagg aactattaac cctttagtgg atatctacaa ttttatctca ttaaaatatg
     3181 cattaccttg tggaggggag gatatagata aatttatagg agatattagg ctaactagag
     3241 caattggtaa tgaggagttt atcccactag ggacagatga aaattcattt ccatatgaag
     3301 gagaaataat ttataaagat gatggtggag caatttgtag atgttggaat tggcgtgaag
     3361 cagtgagaac aatgcttact gaagatacta acaatgcctt tttatgcatt gaattagtag
     3421 atgaaagtag atttaaagaa tttgaaaatg ctttaaatga attagctaaa atagttcaag
     3481 aaaaattggg tgggaattgt aaaatttcaa ttttagatat tgataataaa gaggtatcag
     3541 tggattaata tggaggtgct gttgtaatgg actattctag ttataaagat acttatattt
     3601 agggtaagaa ggtctatttt agatataacg attatcaaag gatataatat agaaaataaa
     3661 aatgtagaat ataaaaagcc tttaaaataa gaaaaaaatg tattttaaag gcttttatta
     3721 tactcttttt tatttgcata attaacaata aaaatatatt gttaattata atatttttat
     3781 ttaaaaacga tataatataa tgtattatac tatatataaa atattttaaa ggagttggca
     3841 tgatgtctaa taaacttata aaaaatttac taagtggtat attacaaatt ttattttttc
     3901 ttttaggatt agtaattgtt gtaggaggat ttaaaagttt tatgtacctc tgttttagtg
     3961 gagaagcaac tctacaaggt actatttatg gaatattaat gtttatttta ggtgtatcat
     4021 attttatcat tataaaatca ttgatagaag tattaggtag ttctgaatat agcctatttg
     4081 taaaagagaa tgtaaaaaga tttaggatta ttggatatct tttgctttta aactctctaa
     4141 ttgagtttat ttcaactttt ggtactactg gaaaaggaat gagatttcta gatttaggat
     4201 ttggatttta ttttactgtt ccagtatttg tatattttat aacttctctg atgagttttg
     4261 taattgcaga tggatttgta aaggcaataa agataaaaga ggataatgat ttaactattt
     4321 aggtgtgaca ctttaatata taggagataa ataacccgaa aagagtgact aactagtaat
     4381 ttaaaataaa atatattagg gtataataca taaactataa tgct
//
LOCUS       DAMJVG010000152         4404 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.157, whole genome shotgun sequence.
ACCESSION   DAMJVG010000152 DAMJVG010000000
VERSION     DAMJVG010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4404)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4404)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4404
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.157"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            51..368
                     /gene="trxA"
                     /locus_tag="PC512_003629"
     CDS             51..368
                     /gene="trxA"
                     /locus_tag="PC512_003629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HDF2443323.1"
                     /translation="MAKVINTSEFRSSVEGSKGVVVVDFFATWCGPCNMLGPVFAELG
                     EEMKDKARFVKVDIDESLEIAQQFNVSTVPTMIIFKDGKPVETLIGFMPKNKIEMQVK
                     SYL"
     gene            385..1263
                     /locus_tag="PC512_003630"
     CDS             385..1263
                     /locus_tag="PC512_003630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDF2443324.1"
                     /translation="MRYDIAIIGSGPAGLSAAINAKIRNKTIIMFGNDNLSNKLVKAP
                     SIDNYLGFYDISGDELKDKFKSHIDSMDISIENKRINNIYAMGEYFTIMSGNDMYEAT
                     TVILATGVEYTRPIKGEEEFLGRGVGYCATCDAPLYRNKKVAVIGYNEESKEEANFLS
                     ELTSKTYFIPMYKKDNLMRSSDNLDDSIEVIHDRPVQIDGDKLVNKVSFKENHIEVDG
                     VFVIKDSTAPSALVPGIEIDGIHIKVDNNMKTSIDGCFAAGDCVGKPYSYIKAAGQGQ
                     IAALNAVYYLDKLKRA"
     gene            1533..1901
                     /locus_tag="PC512_003631"
     CDS             1533..1901
                     /locus_tag="PC512_003631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDF2443325.1"
                     /translation="MENLVKIFKALSDETRLNILILVSKRNICQKGISKYLGISDSAV
                     SQHIKILKDVGIITGYKEGYYVLYHINKESFNICVDFINSMLSNSSESFIDVFDVNTI
                     HLGCSKECKSIKKCCKRREK"
     gene            1904..2275
                     /locus_tag="PC512_003632"
     CDS             1904..2275
                     /locus_tag="PC512_003632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifB/NifX family molybdenum-iron cluster-binding
                     protein"
                     /protein_id="HDF2443326.1"
                     /translation="MKVCIPVEENKGLDSKPYGHFGSAPIFVVCDLESGEVKSLDNGD
                     LDHEHGKCQPLKALSGTAVDAVVVGGIGQGAIIKLNGMGIKVYRAEGDTISANLDLLK
                     NGKLVEFPSDHTCSHDGCGHH"
     gene            complement(2420..2875)
                     /locus_tag="PC512_003633"
     CDS             complement(2420..2875)
                     /locus_tag="PC512_003633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443327.1"
                     /translation="MNINTVQGDSIEVLLRQLGATRISKVSSTLYFIKFDLGDGWEIS
                     YTYNINAKDQYFLQRIEPYPIGRGLFNDEYEIVSFISKDLKKFLNAKNSSNFKTFVEV
                     TRKVNSIIDNVEELFLNYNVDGDDLKTLNKELNDILNDIDYIEKHTKKI"
     gene            complement(2914..4179)
                     /locus_tag="PC512_003634"
     CDS             complement(2914..4179)
                     /locus_tag="PC512_003634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsB/NhaD family transporter"
                     /protein_id="HDF2443328.1"
                     /translation="MEFQQIIAICIFLIVMAAIITEKVNRSVAAVGGALLMIIFNILT
                     LDEGLSHIDFNTIGVLVGMMLFVAVVKNSGLFEYIAIWTAKKAKGDPWKIMICFAIIT
                     AILSAVLDNVTTVLLIGPMTIVITQILGLNPVPFLITQILASNIGGTATLIGDPPNIM
                     IGSAANLSFMDFVINLGPAVIVILAITIICFRFIYGKELVVNERAKNAILKLDEKKSV
                     KDKPLLIKSLILIAFILFGFMFHSTIHIDSSVVALTGASIMLLIGKQDVDEIMAGIEW
                     STILFFMGLFVVVGGLVEVGIINKLAQALIGLTEGHLVFTMLLILWLSAIVSSFLDNI
                     PFVATLIPLILTMQAEGIDVMPLWWATSLGACLGGNGTLIGASANVVLAGIGNKHGHP
                     ISFKEYFKIGFPLMIISIIISTVYLIIKF"
BASE COUNT         1662 a          557 c          673 g         1512 t
ORIGIN      
        1 tcatagtata attatatagg gataataaag tttaatagga ggatttaaaa atggcaaaag
       61 ttataaatac atctgaattt agaagtagtg ttgaaggtag taagggagta gttgtagttg
      121 atttctttgc aacttggtgt ggaccttgta acatgttggg acctgtattt gcagaattag
      181 gtgaagagat gaaggataaa gctagatttg taaaagttga tatagatgag agcttagaaa
      241 tagctcaaca attcaatgta tctacagtac caactatgat tatatttaaa gatggaaaac
      301 cagtagaaac tttaattgga ttcatgccaa agaacaaaat tgaaatgcaa gtaaaatcat
      361 atttataaaa aatgggtgag tattatgaga tatgatatag ctataatcgg cagtggtcca
      421 gctggattgt ctgctgctat aaatgcaaaa ataagaaata aaacaattat catgtttggt
      481 aatgataatt taagtaataa gcttgttaaa gctccttcaa tagataatta tttaggtttt
      541 tatgatataa gtggtgatga attaaaagac aagtttaaat cacatataga tagtatggat
      601 atttcaattg aaaataaaag aataaataat atttatgcta tgggagaata ctttacaata
      661 atgtctggaa atgatatgta tgaagctact actgtaatcc ttgcaactgg ggtagagtat
      721 actagaccaa tcaagggtga agaagaattt ctaggaagag gtgtgggcta ctgtgctaca
      781 tgtgatgcac cactttatag aaataaaaag gtagcagtta taggatataa tgaagaatct
      841 aaagaagaag caaatttttt aagtgaactc acttcaaaga cttattttat acctatgtac
      901 aaaaaagata atcttatgag aagttcagat aacctagatg attctattga agttatacat
      961 gacagaccag tacagataga tggagataaa cttgtaaaca aagtatcttt taaagaaaac
     1021 cacattgaag ttgatggagt attcgttata aaagatagta cagctccaag tgcattggtt
     1081 cctggaatag agattgatgg cattcatatt aaagttgaca ataatatgaa gactagtata
     1141 gatggatgct ttgctgctgg agattgtgtt ggaaaaccat attcttatat aaaagcagct
     1201 ggtcaagggc aaatagcagc tttaaatgct gtttactatt tagataaatt aaagagggct
     1261 taatatttat attgattaac tttttaaaga tatttataaa aaactgtctt gaaataattt
     1321 tattatttca agacagtttt ttatttttaa gttattaata aaagtatttt aaaatctata
     1381 tgtaattact tttattaata aaactcaaag ttatattagt aaaaattgga attatttata
     1441 atatactcca aaatttaaaa ataatggttg aaaaatctaa ttaagagtac tataatttaa
     1501 ttaagtaatt acttaatcaa aacgaggtac ttatggaaaa cttggttaaa atatttaaag
     1561 cattgagtga tgaaactaga cttaacatac ttatattagt atccaagaga aatatatgtc
     1621 aaaaggggat ttctaaatat ctagggattt cagattctgc tgtttcacaa catataaaaa
     1681 tattaaaaga tgttgggata ataacaggat ataaagaagg atactatgtt ttatatcata
     1741 ttaataaaga atcatttaat atatgtgtag attttataaa ttctatgtta agtaattcta
     1801 gtgaaagctt tatagatgta tttgatgtaa atacaataca tctaggatgc agtaaagaat
     1861 gtaaatctat aaaaaaatgt tgtaagagaa gggagaaata ataatgaaag tatgtatacc
     1921 agtagaggag aataaaggat tggatagtaa accatatgga cattttggtt ctgctccaat
     1981 ttttgttgtg tgtgatttag aaagtggaga agttaaatct ttagataatg gagatttaga
     2041 tcatgaacat ggaaaatgtc aaccattaaa agcattgtca gggacagctg tagatgcagt
     2101 agttgttgga ggaataggac aaggagctat aattaaatta aatggaatgg gaataaaagt
     2161 ttacagagca gaaggtgata ctataagtgc taatttagac ttacttaaaa atggaaaatt
     2221 agtagaattt ccatcagacc atacttgctc acatgacgga tgtggacatc attaaaaaaa
     2281 aacagctgat gaaatatata cttcatcagc tattttttct tttaataaat acgattttat
     2341 tcttttaaaa ccaaaattta gatttttata ttttttgtag tatccttaat aatatttcaa
     2401 gtttacaagt ttactacttt tagatttttt ttgtatgttt ttctatatag tcaatatcat
     2461 ttaatatgtc attgagttct ttattaagtg tttttaaatc atcaccatct acattgtagt
     2521 ttaaaaatag ttcctctaca ttatcaatga tagaattgac ttttctagta acttcaacaa
     2581 atgtcttaaa gttactacta tttttagcat ttagaaattt ttttaaatcc tttgatataa
     2641 atgatactat ttcatattca tcattaaata gacctctacc aataggatat ggttcaattc
     2701 tctgtaaaaa atattggtct ttagcattaa tattataagt ataagatatt tcccaaccgt
     2761 ctcctaaatc aaacttgata aaatataatg tactacttac ttttgatatt cttgtggcac
     2821 caagctgtct taaaagaact tcaatcgaat caccttgaac agtattaata ttcatatata
     2881 cacatcccct ttagtattat tatactatat tttttaaaat tttataatta aataaacagt
     2941 agatataata atagatataa tcataagtgg aaaacctatt ttgaaatact ccttaaaaga
     3001 gataggatga ccgtgtttat tacctatacc tgctagtaca acattagcag atgctcctat
     3061 tagtgttcca tttcctccaa gacaagctcc aagagatgtt gcccaccata gtggcattac
     3121 atcaatacct tcagcttgca tagtcaaaat aagaggaatt agtgttgcaa caaatggaat
     3181 attatctaag aaagaagaga ctatagctga caaccataat atcaacaaca ttgtaaatac
     3241 aagatgtcct tctgtaagtc caatcaatgc ttgagccaat ttgtttatta tcccaacttc
     3301 tactaatcca ccaactacta caaataatcc cataaagaat aaaattgtag accattcaat
     3361 acctgccata atttcatcta catcttgttt tcctattaaa agcattatag atgctcctgt
     3421 cagtgctaca acagaagaat ctatgtggat tgtactgtga aacataaaac caaaaagtat
     3481 gaatgctatt aatataaggc tttttataag tagaggttta tctttaacag attttttttc
     3541 atctagtttt aatattgcat ttttagctct ttcattcaca acaagttctt ttccataaat
     3601 aaatctaaag catattatag ttatagcaag tattactata acagcaggac ctaaatttat
     3661 tacaaaatcc ataaaactaa gattggcagc actaccaatc ataatatttg gagggtctcc
     3721 tataagagta gctgttcctc ctatatttga agctaaaatc tgtgttatta aaaatggaac
     3781 tggattaagt cctaatattt gtgtaataac tatagtcatt ggtccaataa gtaagacggt
     3841 tgtaacatta tctaatacag ctgataaaat agctgttata atagcaaagc aaatcattat
     3901 cttccatggg tcacccttag ctttctttgc agtccagata gctatatatt caaataaccc
     3961 cgagtttttg acaacagcta caaatagcat cataccaact aatacaccaa tagtattgaa
     4021 atctatatgg cttaatcctt catcaagtgt aagtatattg aatattatca ttaatagtgc
     4081 accaccaaca gctgctacgg atctgtttac cttttctgta ataatagctg ccataactat
     4141 taaaaatata catatagcta ttatttgttg aaattccata atataagtac ctccatttgt
     4201 attattttgt gcctaatgct agtactatat atagtattac ttttttattg ttttttcaat
     4261 ggatgtatga aagtatatta tttaacaaag tttttgaaaa attgacagaa tttaaagaaa
     4321 atttttgtta tttaaataaa ttttaaaatt attccattga taataatatt aaacgacaaa
     4381 cgaaaaaata taccctttaa acta
//
LOCUS       DAMJVG010000153         4289 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.158, whole genome shotgun sequence.
ACCESSION   DAMJVG010000153 DAMJVG010000000
VERSION     DAMJVG010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4289)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4289)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4289
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.158"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            231..1310
                     /locus_tag="PC512_003635"
     CDS             231..1310
                     /locus_tag="PC512_003635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HDF2443329.1"
                     /translation="MPELLKNMYNRESLYEVAVAIQSVYNSFKVDEFIKSTMDETWNN
                     LELKARCRKISMSLGMYLPEDYKEALSILEKSVTGFYFAFFFPDFVEVYGQDDINWDL
                     SISALERNTEYWSSEFAVRAFIIKDEERMMAQMRKWSKHKSEHVRRLASEGCRPQLPW
                     GQAISKFKKDPTPVLPILEQLKTDTSTYVQKSVANNLNDISKTHPDLVISIAKDWYGK
                     NKSTNWIVKHGCRTLLKKGNRDVLALFGYDDTTSINLQDFTLETTSISIGEDLTFSFN
                     ILAKKATKTRLEYGIDYIKSNGKRNRKIFKISEVSLKENEKKSYMKKHSFADVSVRKH
                     YPGIHSIAIIINGIEKDKLDFELGI"
     gene            1634..2002
                     /locus_tag="PC512_003636"
     CDS             1634..2002
                     /locus_tag="PC512_003636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HDF2443330.1"
                     /translation="MDVYSFWNDTLAQDAVKIRKYFHENAYINWHDTNEHFTLEEFII
                     ANCEYPDKWNGKVEKVLEFGNLVITVTHVYAINKPLSFHVVSFISLKDDKIISIDEYW
                     GEDNDVPQWRLDKHIGKPIK"
     gene            2119..2922
                     /locus_tag="PC512_003637"
     CDS             2119..2922
                     /locus_tag="PC512_003637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2443331.1"
                     /translation="MEEKYILSDRGKVYYWIKESNSVFAKNLIFLPGLTANHHLFDFQ
                     IQYFSKNHNVLVWDAPAHGKSRPYLDFSYSNLVEELKVILDKQNMKKVVLIGQSAGGF
                     VAQSFIVKYPNMVEGLMMIGTCPYGTDYYSKSDIFWLKQTEWMLKLFPDKFLRNIISK
                     MCGATSEGRRSMMKMLEGYEKKELCHLMYLGFAGFIPEIQDLNIHCPVCLVVGDKDKT
                     GKVRKYNEQWHNKTGYPLHIIKNASHNVNVDKPNELNQIMDIFIKQLNI"
     gene            3307..4197
                     /locus_tag="PC512_003638"
     CDS             3307..4197
                     /locus_tag="PC512_003638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF2443332.1"
                     /translation="MIESIPAKQILQKVKFDNTRWFGIDYNMNLYRGCSHGCIYCDSR
                     STIYNIENFDKVRYKENVIEILSKELRSKRKKGVVGIGAMSDTYNPFEKQLCITKQAL
                     DLISENHFGVSIDTKSSLVVRDIPILQKIKKNNSAIVKLTITTANDELSKKIEPYVNP
                     SSVRFEAVKELNDSGIFCGILLTPMLPFLTDTKDEIRAIVEKAHKANAKFIYCMYGVT
                     MRSGQREFFYEHLRDISPKLVFKYQKTYGLNYVCTVQNKDCCEKLLREECARYGILTD
                     MKDIIKAYKRSESYTQIKFF"
BASE COUNT         1642 a          470 c          803 g         1374 t
ORIGIN      
        1 cagtaaagta taaaattcta ttactataat aaaagataga actagaagtc tttatgaaag
       61 tgggaaaagt atttatataa ataaattcat atagtttata gtttaatagt aggaaatatc
      121 gtatgagtaa gaatattgta ttttacataa agatttagca atatgacaca ctgttgtcgt
      181 gttctgtagg atatgattaa taaatcagat atgaaaggag agtgagtaat atgccagaat
      241 tactaaaaaa tatgtataat cgtgagtcac tttatgaagt tgcagtagct atccaatcag
      301 tttacaactc atttaaggta gacgagttca taaaatctac aatggatgag acatggaata
      361 acttagaatt aaaagccaga tgtcgaaaga taagcatgag tttaggaatg tatttaccag
      421 aagactataa ggaagctctt tccattcttg aaaaatcagt tacaggtttt tattttgctt
      481 ttttctttcc agattttgtt gaagtttatg ggcaggacga cataaattgg gatttatcta
      541 taagtgcatt agaaagaaat actgagtatt ggtcttcaga atttgctgta agagcattta
      601 tcatcaagga tgaagaacgt atgatggcac agatgcgtaa atggtctaag cataagagcg
      661 aacatgtacg aagacttgca agtgaaggtt gtcgtcccca gttgccttgg ggacaagcaa
      721 tatccaaatt taaaaaagac cctacacctg tgctacctat attggagcaa cttaaaacag
      781 atacatcaac gtatgtacaa aagagtgttg ctaataatct aaatgatatc tcaaaaacac
      841 atccagattt agtcataagc attgcaaagg attggtacgg taaaaataaa tctactaact
      901 ggattgtaaa gcatggttgt agaactctac taaaaaaagg aaatcgtgat gtattagccc
      961 tttttggata tgatgatact acttctataa atcttcagga ctttacttta gaaacaacgt
     1021 ctatttctat tggagaggat ttaacttttt catttaatat tttagcaaaa aaagcgacaa
     1081 aaacaaggct cgagtacgga attgattata ttaaatctaa tggaaaaagg aataggaaga
     1141 tatttaaaat atcggaggtt tcattaaaag aaaatgagaa aaagtcatat atgaaaaaac
     1201 attcatttgc agatgtaagt gtaaggaaac attatccagg tatacactcg attgctatta
     1261 ttattaatgg tatagaaaaa gataaacttg attttgaatt aggtatataa ttttactaac
     1321 agaataatct atatcagata ctttgctaaa cttatataat atattttact aaatttatat
     1381 taggtagttt actacttgtt tactgaattt aaatacaaag aaatacaggt gctaatccct
     1441 gcccattaaa ggaatatgag cataacacaa aagtagaact tatcaattct gttacgggta
     1501 tagtagtaaa tccatagaat cacaattaga agatgaagtg taaaaaataa gttagtgttg
     1561 attttagttg ctagtgatat tgaatagtta tacaatagct atataaatta gaatttgtag
     1621 aggagaaatg taaatggatg tatatagttt ttggaatgac actttagcac aagatgctgt
     1681 taagataaga aaatattttc atgaaaatgc ttatattaat tggcatgata caaatgagca
     1741 ttttacttta gaagaattta ttattgcaaa ttgtgagtat cctgataaat ggaatggtaa
     1801 agtagaaaag gtgctagaat ttggaaattt agtaattaca gtgacacatg tttatgcaat
     1861 aaataaacca ctatcatttc atgtcgtttc atttatcagc cttaaagatg ataagattat
     1921 ttctattgat gaatattggg gagaggataa tgatgtgcca cagtggagat tagataaaca
     1981 tattggaaag ccaataaaat agtttttgtt ctgttttata actgaaattt tgataacatt
     2041 tgatattttg atttgtcatt ggtcaacata gtcgttagtg taataattta aaaaagtaga
     2101 atttggagag tgaacactat ggaagaaaaa tacatcttat ctgaccgagg gaaagtatat
     2161 tattggataa aagaaagtaa tagtgtgttt gcaaagaact taattttttt gccaggacta
     2221 acagcaaatc atcatctttt tgatttccaa atacagtact tttcaaaaaa tcataatgta
     2281 ttggtatggg acgctcctgc tcatggaaaa tcaagacctt acttagattt ctcatattct
     2341 aacttggtag aagaattgaa agtaatttta gataaacaaa atatgaaaaa ggttgtactt
     2401 atagggcaat cggcaggggg atttgtggca cagtccttta ttgtaaaata tccaaatatg
     2461 gtagaaggac taatgatgat tggaacttgt ccatatggaa ctgactatta tagtaagtca
     2521 gatattttct ggttaaaaca gactgaatgg atgttaaagt tattcccaga taaatttttg
     2581 cgaaacataa tatctaagat gtgtggagct acgtctgaag gcagaaggag tatgatgaaa
     2641 atgttagaag gctacgaaaa aaaagaactg tgtcatctca tgtatctggg atttgctggg
     2701 ttcataccag aaattcaaga cttaaatata cattgtccag tttgtttggt ggttggagat
     2761 aaagacaaga cgggtaaagt gagaaaatat aatgagcagt ggcacaacaa gactgggtat
     2821 ccattgcaca ttataaaaaa tgcttcacat aatgtaaatg tcgataaacc taatgaacta
     2881 aatcagatta tggatatatt tattaagcaa ttaaatatat aaaaattaca tactcattag
     2941 gtaaattatg tagtatatgt gtttatagat ggttatagaa ataaatatgt aataaactac
     3001 ttaacactta aaaagtggat ttgtccagag cataatacaa agcatgatat ataaattttt
     3061 aagcgaaata catcaaaaga agtattagaa ttagtggaga taaaacagct attagagatt
     3121 ataaataaat agttttaaag gtactacgaa tatagaggaa ggtaaatcat acgttattca
     3181 aggattataa atgattagtt taaaagtact atcggacagg tctctgcata tttaaacctt
     3241 agtaaaggta gttaaagtag tagtttaaaa actaaaaaat tatataaagg aattaggtat
     3301 aagaaaatga ttgagagtat accagcaaaa caaattttac aaaaagtgaa atttgacaat
     3361 acaagatggt ttggaattga ctataatatg aatctctatc gtggttgttc tcatggatgt
     3421 atatattgtg atagccgtag cacaatatac aacatagaga attttgacaa agttagatat
     3481 aaagaaaatg tgatagagat tttaagtaaa gaattgcgtt caaaaagaaa aaaaggggta
     3541 gtaggcattg gagctatgtc tgacacatat aatccttttg aaaagcaact ttgtattaca
     3601 aagcaggcac tagatttgat ttcggaaaat cattttggag tgtctattga tactaaaagt
     3661 agtttggtgg ttagagatat accgattttg cagaaaatta aaaaaaataa ttctgctatt
     3721 gtaaagttga ctataaccac tgcaaatgat gaattatcaa agaaaataga accttatgta
     3781 aatccaagtt ctgtacgatt tgaggcagtg aaagaactta atgattctgg aattttttgt
     3841 ggtatattat tgactcctat gcttccattt ttgactgata ctaaagatga aatacgagca
     3901 attgtagaaa aagcacacaa ggctaatgca aaatttattt attgtatgta tggtgtaaca
     3961 atgcgtagtg gtcagcgaga gtttttttat gagcatttaa gagatatatc accaaaattg
     4021 gtatttaaat atcagaaaac atatggttta aactatgtat gtactgtaca aaataaagat
     4081 tgttgtgaga agttgttaag agaagaatgt gcacgttatg gtattttgac ggatatgaaa
     4141 gatattataa aagcgtacaa gaggtcggag tcatatactc aaataaaatt tttttaagat
     4201 aggctttgga tgagatataa tagtggtgat tgatgtgttg atattatagt tgattgttag
     4261 agaggatatt atagatgaat attagtatt
//
LOCUS       DAMJVG010000154         4133 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.159, whole genome shotgun sequence.
ACCESSION   DAMJVG010000154 DAMJVG010000000
VERSION     DAMJVG010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4133)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4133)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4133
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.159"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            168..1571
                     /locus_tag="PC512_003639"
     CDS             168..1571
                     /locus_tag="PC512_003639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDF2443333.1"
                     /translation="MEKKKIGLWSLVFMNVSALYGIRWIAKSTASSFGLGLGAIPMWL
                     LFSFIYFVPGALICAELASTYQKGDGGLYDWVKEAFGEKYGFLVSWLNWTAKIFWYSS
                     FLTFLAVNVSYTIGNPALADNKMFVLILSLIIFWALSLIATKGISFTKIFTNTGALGS
                     TIPSAILIIFSFVAVFVLKKHDIASTYTIASMTPKLNMDAFVAISAIMFGLAGAETAA
                     NFITEIDKPEKNFPKAILISAGIVASLYVLGSIAITMIIPPDQITASKGVLDALSAVC
                     ASLGIGSWLVQLIAFGIAFSVLGAIVLYIASPIKMLFGSVKKGIFPDSLVEVNEHKIP
                     SKAVILQAIIVTIILLVTTLMPSVDAIYNVLVTMTALTALFPYVLLYASYIKLRKERP
                     DEIRPYTMAKSTSTCLGLAKMVLVVTVVGILLSAAPVMPTFAENVIYEIEMIGGGLLV
                     ILSGLWLWNRYEKKTAK"
     misc_binding    1662..1902
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1945..2643
                     /locus_tag="PC512_003640"
     CDS             1945..2643
                     /locus_tag="PC512_003640"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HDF2443334.1"
                     /translation="MNVIGIIGAMDEEVSILVDLMDIRETIKKASLEFYKGILEGKNV
                     VLVKCGIGKVNSALCAQILISEFKVDAIVNTGVAGALNEKLDVNDIVISTDAIQYDVD
                     TTAFGDPKGVIPRMKTSVFKADERLIDAAYKSSVEEVKTHKVLKGRVVTGDKFINSKE
                     LKEELVNDFGGYCGEMEGGAIAHVCYLNNTPFVIIRAMSDKADGSADVTYDVFVHDAA
                     NNSKDIVLNMLKSI"
     gene            2666..3667
                     /gene="trpS"
                     /locus_tag="PC512_003641"
     CDS             2666..3667
                     /gene="trpS"
                     /locus_tag="PC512_003641"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HDF2443335.1"
                     /translation="MSEKKVILSGAQPSGKMTLGNYLGAIKNWTELQDNYDCYYSIVD
                     LHAITVPQDPKVLRANTIELLAQYIACGLDPEKNTIFIQSHVKEHVELMWVLNTMTYM
                     GELSRMTQFKDKSQKSEANLNAGLFTYPVLMAADILLYQTDLVPVGDDQKQHLELARD
                     LANRFNNRFSPTFVVPEGYYPKGGARVMSLQEPTKKMSKSDSNENAFILLADDSDSIK
                     RKIKRSVTDSLGVVKYNDEQPGIKNLIDIYSNLSKKSVEEIVNMYEGKGYGIFKEDVA
                     EVVSEALRPIREKYVDLLNNKDYLEKIYSMGAEKAEKQARKTLRKVYKKVGFIERRY"
BASE COUNT         1555 a          459 c          736 g         1383 t
ORIGIN      
        1 tatcattttt aataagattt gatttcaaag tatttaaggt ttattattaa aactgttttt
       61 gaatatgcaa atattttgaa aaatatcagt ttaataataa tgaatctatt ttattaattt
      121 tgaaattaaa tttaaaataa ttaatagaga ggggaaatta aattaggatg gaaaagaaaa
      181 aaataggcct atggagtttg gtatttatga atgtatcagc tttatatggt ataagatgga
      241 tagctaaatc tacagcatca agctttggtt taggattagg tgcaatacct atgtggttat
      301 tattctcatt tatatacttt gtaccaggag ctttaatttg tgctgaatta gcttctacat
      361 atcaaaaagg tgatggaggt ctttacgatt gggttaagga agcctttgga gaaaagtatg
      421 gatttttagt ttcttggtta aactggacag ctaaaatatt ttggtattct tcatttttaa
      481 ctttcttagc agtaaatgtt tcttatacaa taggaaatcc agcccttgct gataataaga
      541 tgtttgtact tatattatct ttaataatat tctgggcatt atctcttata gcaactaaag
      601 gaataagttt tacaaaaata tttactaata caggtgcatt aggttcaaca ataccaagtg
      661 ctatacttat aatattttca tttgtagcag tatttgtatt gaaaaaacat gatatagctt
      721 ctacatacac aatagcttca atgactccaa aacttaatat ggatgcattt gttgctatat
      781 cagctataat gtttggttta gcaggagcag agactgctgc taacttcata acagaaatag
      841 ataagcctga aaagaacttc cctaaggcaa tattaatatc agctggaata gtagcttcat
      901 tatatgtatt aggttcaatt gcaataacaa tgataatacc accagaccaa attactgctt
      961 ctaaaggtgt attagatgca ctttctgctg tttgtgcgtc tttaggaatt ggttcttggt
     1021 tggttcaatt aatagctttt ggtatagctt tttcagtatt aggagcaata gttctttaca
     1081 tagcatcacc aataaaaatg ttatttggta gtgttaaaaa aggaatattt ccagatagtt
     1141 tagtagaggt aaatgaacac aagatacctt ctaaagcagt tatacttcaa gcaataatag
     1201 ttactataat actattggtg actacattaa tgccttctgt tgatgctata tacaatgttc
     1261 ttgtaactat gacagcatta actgcattat tcccatatgt attgttatat gcttcttata
     1321 ttaaactaag aaaagagaga ccagatgaaa ttagacctta tactatggca aaatcaacaa
     1381 gtacttgcct aggtttagca aaaatggttt tagttgtaac tgtagtgggt atattattat
     1441 ctgcagcacc agttatgcct acatttgctg aaaatgttat atatgagata gagatgattg
     1501 gtggaggtct tctagttata ttatctggtc tatggttatg gaatagatat gaaaagaaaa
     1561 cagctaaata aaatgtattt taaaaatttc ttttggatat tataatatat agttgacaat
     1621 ttatagtgta aggaatatta taaaataaag aaattaataa attaaatcct gagataagaa
     1681 atagtaaata aatatatttt tgcacagaga attaaggatg ctgagaactt aataaaaagt
     1741 atttattgaa tgggtctttg aggagtaaaa tgaaatgtaa tttaagatta cagagtattt
     1801 gatatcgtgt atgcacgtta tagcatatat taagatatat atattcaatt ttgagtgtat
     1861 ataaatttag gtggtaccac ggaaaatata tccgtcctat tgatttagga cggatttttt
     1921 aatatagaaa atttaggagg aaaaatgaac gtaataggaa ttataggtgc aatggatgaa
     1981 gaagttagta ttttagttga tttaatggat attagagaga ctataaaaaa agctagctta
     2041 gaattttata agggaatttt ggaaggtaag aatgtagtgt tagtaaagtg tggcataggt
     2101 aaggttaact ctgctctttg tgcccagata ctaataagcg aatttaaggt tgatgctatt
     2161 gttaatacag gtgttgcagg agctttaaac gaaaaacttg atgttaatga tatagtaata
     2221 tcaactgatg ctatacagta tgatgtagac actacagcat ttggagaccc taagggagtt
     2281 ataccaagaa tgaagacttc tgtatttaaa gcagatgaaa gacttataga tgctgcttac
     2341 aaatcttctg tggaagaagt aaagactcat aaagtattaa aaggaagagt agttacagga
     2401 gataaattta taaattctaa agaattaaaa gaagaattag taaatgattt tggtggatat
     2461 tgtggagaaa tggaaggtgg agctatagct catgtatgct atttaaataa tactccattt
     2521 gtaataataa gagcaatgtc tgataaggca gatggaagtg ctgatgttac ttatgatgta
     2581 tttgtacatg atgctgccaa taactctaaa gacatagttt taaatatgtt aaaatcaata
     2641 taaatatata aggaggtaca aaaaaatgag tgaaaaaaaa gttatattaa gtggtgcaca
     2701 gccatcaggc aaaatgactt taggaaatta tttaggagct ataaaaaact ggactgaact
     2761 tcaagacaat tatgattgtt attatagtat agttgatttg catgcaataa cagtacctca
     2821 agaccctaaa gttttaagag ccaatactat agaattactt gctcaatata tagcttgtgg
     2881 attagaccca gaaaaaaata ctatatttat acaatcacat gtcaaagagc atgttgaact
     2941 tatgtgggta ttgaatacta tgacttatat gggtgaatta agtagaatga ctcaattcaa
     3001 agataaatca caaaagagtg aagcaaatct aaatgcaggt ttattcacat atccagttct
     3061 tatggctgct gacatattgt tgtatcaaac tgacctagtt ccagttggag atgaccaaaa
     3121 acaacattta gaattagctc gtgatttagc aaataggttt aataatagat tttcacctac
     3181 ttttgtagtt ccagaaggat actacccaaa aggtggagca agagtgatga gtttgcaaga
     3241 gccaactaaa aaaatgagta aatccgattc aaatgaaaat gcatttatac tattagcaga
     3301 tgattcagat tctataaaga gaaagataaa aagaagtgtt actgattctt taggtgttgt
     3361 aaaatacaat gatgaacaac caggtattaa aaacctaatt gatatatatt ctaatttaag
     3421 taaaaagagt gtagaagaga ttgtaaacat gtatgaagga aagggttatg gcatatttaa
     3481 agaagatgtg gctgaagtag tatcagaagc tttaagacct ataagagaaa aatatgttga
     3541 ccttcttaat aataaagatt atttagaaaa aatatatagt atgggagcag aaaaagccga
     3601 aaaacaagct agaaaaactc ttagaaaagt ttataaaaaa gttggattta tagagagaag
     3661 atactaatta ttagctatct ttacttgata aataaatttt aaagttatta aaaaggtata
     3721 tgatatgaaa gagagagtct caaagtgaac ttttgttcat gaggcactct tttttgtatg
     3781 aaataaaata tattttaatc atttcaacaa tgaaaaagag gattatctct attttgagac
     3841 agcatctttt gataataaaa aaagatgagc ttttgctcat ctcaaagggg ttagattatt
     3901 cttactttgg ggaaagtaga ataaaggtaa aagttaactg atgtcaactt tgtctttttt
     3961 gcatatcact actgagcata aaaaaatcag aaaaccatag ccttctgaaa caacttctaa
     4021 catacattgt attttatacc caatatgtaa tttatgagtt aattttaact cttataatga
     4081 aaattgtcaa taatatatca aaaaaatatt ttttaaattt atataattaa atg
//
LOCUS       DAMJVG010000155         4115 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.160, whole genome shotgun sequence.
ACCESSION   DAMJVG010000155 DAMJVG010000000
VERSION     DAMJVG010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4115)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4115)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4115
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.160"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            232..1371
                     /locus_tag="PC512_003642"
     CDS             232..1371
                     /locus_tag="PC512_003642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HDF2443336.1"
                     /translation="MVIKLTIEEYKNKYFTGNKIVLSINSFDNKELYYHETENILNLI
                     NEIDKLTSSKIFKTIEDKNDLALESYYSSVIEGAFSTRKIAKSIIRGKMKPSNKSEYM
                     IYNNHRALEYGLDNLDKLYSHKFIYDLHHILGENCLDSEEYEYRTEKVYVCDSKGEII
                     HTGLEPLKIYDFMSKLIDFMENSKVSNLIKSAIIHFYFVYVHPFSDGNGRTSRALSYL
                     YLIDKGYDTFKDFSISYMISKNRTKYYKAILDVENKGNNLTVFIEFMLKSIIQSINEM
                     RNMHDRKSLESILKEELFENDITLSATEEHILKYICNKDNYSMTLENYIKKNKSRYLK
                     AGIKEIELVDQLMEVFNNLEEIEILSKEKNIYKVNDKYLKMLDID"
     gene            1397..1585
                     /locus_tag="PC512_003643"
     CDS             1397..1585
                     /locus_tag="PC512_003643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443337.1"
                     /translation="MNNKKKAFLISGAINVISLIIVFSLFHYNIIENSTQNMIITVIL
                     IFIFEMIKIKIIEKYYKL"
     gene            2369..3925
                     /locus_tag="PC512_003644"
                     /pseudo
     CDS             2369..3925
                     /locus_tag="PC512_003644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860844.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein CwpV"
BASE COUNT         1771 a          422 c          664 g         1258 t
ORIGIN      
        1 ttgttaagac attgtcgaga tattataata tgtaactaat gtattataaa taatagttgt
       61 aaacttcctg tgacatatat tttaaatgct tattcttaaa tttttgcatt atttattaaa
      121 atttattatg ctttaacgct aaattgagtt tgataattat aaaacaaata atcaaaaata
      181 gtgtaaaaat taatactttt tgttaatatt aatagataaa gataatctaa ggtggtgatt
      241 aaactgacaa tagaagaata caaaaacaaa tactttactg gaaataaaat cgtactttct
      301 ataaatagtt ttgataataa agaactatac tatcatgaaa ctgaaaatat attaaattta
      361 ataaatgaaa tagataaatt aacatcaagt aagatattta aaacaataga agataaaaat
      421 gatttggcac tagagtctta ttattctagt gtaatagaag gtgctttttc aactagaaag
      481 attgcaaaat ctataattag aggaaagatg aaaccaagta ataaaagtga atatatgatt
      541 tacaataatc atagagcctt agaatatgga ttagacaact tagataaatt atatagtcac
      601 aaatttatat atgatttgca tcatatattg ggcgaaaact gcttggattc agaagaatat
      661 gagtatagaa ctgaaaaagt atatgtatgt gattcaaaag gtgagattat acatacaggg
      721 cttgaacctt tgaagatata tgactttatg agtaaattaa tagattttat ggaaaatagc
      781 aaagtaagta atttaattaa aagtgctata attcattttt actttgtata tgttcatcct
      841 tttagtgatg gtaatggaag aacatcaaga gccttatcat atctatattt gattgataaa
      901 ggatatgata ctttcaagga tttttcaata tcatatatga tatctaaaaa cagaactaag
      961 tattataagg ctatacttga tgtagaaaac aaaggaaata atttaactgt atttatagaa
     1021 tttatgctca agtctataat acaatctatt aatgagatgc gtaatatgca tgatagaaaa
     1081 tctttagaaa gtatattaaa agaagaattg tttgaaaatg acataactct atcagcaaca
     1141 gaagaacata tattaaaata tatttgcaat aaagataact attctatgac attagaaaat
     1201 tatataaaaa agaataaaag tagatactta aaggctggaa taaaggaaat tgaattagtt
     1261 gaccagttga tggaagtgtt taataatctt gaagagatag agattttgtc taaagaaaaa
     1321 aatatatata aagttaatga taagtactta aaaatgcttg atatagacta atttagataa
     1381 tctggagagg gaatatatga ataataagaa aaaggcattt ttgatttctg gggctataaa
     1441 cgtaatttca ttaattattg ttttttcatt gtttcattat aatattatag aaaatagtac
     1501 acaaaatatg ataataactg taatcttaat ttttattttt gaaatgataa aaataaaaat
     1561 catagagaaa tactataaac tataaacaag aaatatcttt tctaagagca tattgtacaa
     1621 tatgctctta atttagttat atagatttaa tataaataat gtattttttg tagatgattt
     1681 atgtaagatt tatgaccaat ttgtgtatga tttgtgttct ttaatcatga caatattata
     1741 ttgtaaaaaa taaatttaat aaaaaatgac ttggaattta tattctaggt cttttttata
     1801 taaaaattta ataagtttca aatgttggta actttgacag tagaaaacgt ctattgagat
     1861 aacgaggatt ctaattgagg gggagagata ttagcactta aagtagtata tgcaacagat
     1921 ataatcttta caaaagtaat ttgaattaaa atgtaaatat aaagaataat taaaaaaata
     1981 tcgcaattat ttgtttttca tatggataaa attggttatt taatatataa ttacaagtat
     2041 aaataataaa atttatttgt aaaaagagta gcactttaat tcataaaggc tacttttttt
     2101 atacaaaacc ctatttttta taacaattca ttaacataaa aatcaaactt accttaaaat
     2161 ataaatttac aaatttttca atcaataaga aaatttcttt attccttaca taatgactgc
     2221 aatgtaacaa aataattaca aattaattat gaaatcatta tagttagaaa cctctttaaa
     2281 attagatatt aagtatcctt tagaattaga acgggaacaa agttaaaaaa ttaagtaata
     2341 tcaaatggac aagggggaag aaaataaaat gaaaatacca aagaagattg ctgcaatgct
     2401 tacagttaca atgatagctg gaagttcaac agcaggcata gctagtgcac aaactgtggc
     2461 aacaaattta acagggcaag aaagatatga aactgctgtt aaaataagtc aagatggatg
     2521 gaaaaatgct gatgaggtag taatcgtaaa cgactcatct atagcagatg ctctatctgc
     2581 aacaccattt gcaaaagcaa aaaatgctcc aatactttta acaagtaaag ataaattaaa
     2641 tgataagacg aaagcagaaa tacaaagatt aaaagctaaa aaagtatact taataggtgg
     2701 aacttctgta ttaagtacaa atatagaaaa agaaataaaa gatttaaaaa tatcttttga
     2761 gagaatctct ggagctgaga gatatcaaac atccttagaa ttagcaaaga aattagatgc
     2821 tataagtgat gttaagaaaa tagctgtagt taatggtgaa aaaggacttg cagatgctgt
     2881 aagtgtagga gcaccagctg cacaaaacaa tatgccagta atacttgctg attctaaaaa
     2941 tggaacagca gttgcagaca aatttataaa agatgctgga ataactcaat cttatgtagt
     3001 aggtggagag agttcaattt ctgaagctgt taaaaataaa ctaccaaata gtacaagact
     3061 aggtggaaca gatagaaatg atacaaatgc aaaagtaata aaagaatttt ataaaaagac
     3121 agatttaaaa aatgcttatg taactaaaga tggtatgaat aaacaagacc aacttataga
     3181 tgcactagca gtaggtgtat taggtgctaa aaatcaatca ccagtagttt tagttggaaa
     3241 gaacttatca gcttcacaaa aatctctagt taactctaag agttttgata agataactaa
     3301 agttggtggg aatggtaatg agacagcatt taatgaaatg aagtcattac aagaagtaaa
     3361 aacagttgaa gctaaaacaa tttctgaatt aaaatcagct atagataaag ctactgctaa
     3421 tgatgttata aactttaagc caactagtga ggttaaagaa gcatttacaa tacaaactga
     3481 taaagcagta acagtaaact taaatggtac atatacaaag actgtaacta tcaacatgcc
     3541 taatggagat gtaaataact atgcaaaagt ggatgatgta gttatagatg atgtaaaaga
     3601 tggaactttt gttaactatg gaaaaataac taacttaaag gttaatgata aaaatggagc
     3661 caagatagaa aataattcta aaggtgagat tggtagttta acagtagcat ctggagcaag
     3721 tcaagtaaaa gtgactaatg gtggtaagat aactacagtt acaaataatt ctaaagggac
     3781 tactatagat aataaaggta caataagtag tgttaaggga gataattctc caacaataag
     3841 tggaaatagt ccaagttcta actcttcagg aggaagttca tcaagtggag gctcttcaca
     3901 tggaggagga agttcttcat caaaaccaag cgataagtca aaaacaaaga caaaagcaga
     3961 agaaaaaata gcagaggtaa caaaactagt aggaaaagta acagcagata atttagaagc
     4021 atcaaaagta acattaaaag cagcaactga tgcaatagaa gaagcaagga aagcagggtg
     4081 gacagaatca gaagttcaaa gctttaaagg atatg
//
LOCUS       DAMJVG010000156         3902 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.161, whole genome shotgun sequence.
ACCESSION   DAMJVG010000156 DAMJVG010000000
VERSION     DAMJVG010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3902)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3902)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3902
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.161"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            239..1864
                     /locus_tag="PC512_003645"
     CDS             239..1864
                     /locus_tag="PC512_003645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012100074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HDF2443338.1"
                     /translation="MYNVIDLFAGAGGLSLGFEMTKKFNMVAFVEKNDNAAKTYLENH
                     PSVKRYCDIKRLDFQDILNSVDKIDVVIGGPPCQGFSNANRQKRKIINGNNELVKLYV
                     DAIDKLKPNVFVMENVKTISSNKHSFYLTKKDKNHIINNLKLNIYNKDSVLYDRTEYI
                     NELFNIISIEDIESYIISNIDLKNLKIIIKKKKDICDYLNKISNYKKVKSTIEKLETR
                     GKMPKWYLELINKVKNILENMLYNRNLSDEQIFYLNLFLDIQNLFLGIYELKSESVIF
                     ENTLDDNKIIAKMDTYIIIDYINASFEYLGYVLNGSALNSIDYGVPQNRERFVLIGAK
                     KDFLKNKKIETPKPIVGENYVTVRDAIGDLAEYEASKGSMDYCFEKNSNNIEKDFYRK
                     IILDSNKIYNHVCTDTRNIALKRFEYINQGNNFHSLPDELKGTYADPERTQNTIYKRL
                     VYDKPSDTVVNVRKSMWIHPIKNRAVSAREAARLQSFPDSYKFLGTKDSVYQQIGNAV
                     PPLLGRVVAEKILNLFNDEPNEYLRDVFEALDG"
     gene            complement(2864..3436)
                     /locus_tag="PC512_003646"
     CDS             complement(2864..3436)
                     /locus_tag="PC512_003646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class B sortase"
                     /protein_id="HDF2443339.1"
                     /translation="MEKLVKILINIICIIALTFSSLSIYIKLSEYKKADEVYTELREN
                     TINNSKHQELYDKNNDYRFWLKINNVNINYPVVQGYNNDFYLTHDFYKNYLPLGSIFM
                     DYRNNFENDKSLIVYGHYMKNKTMFGQLENYTDEVFFKENNLVEINYKVQTYTYEIFS
                     VYTADLINRDYLSIHFNNNDEFKYSLNYIT"
     gene            3705..>3902
                     /locus_tag="PC512_003647"
     CDS             3705..>3902
                     /locus_tag="PC512_003647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443340.1"
                     /translation="MQQKCKKKALSMILSISMGLGSVASFNASNTFADTIEESTNAGN
                     AEGDTNAGNAEGDTNAGNAEGD"
BASE COUNT         1566 a          399 c          554 g         1383 t
ORIGIN      
        1 aataatatat ggtatataat ataaaaaaag attgataaat aaataaaaaa tatattatgt
       61 tatttatttg aatagattat ccagaagaca taaataagaa aaataatgtg taagtaaaaa
      121 tattagaatt tattaaaagc tattacaagt ataagaaatt tgaaatgatt attcaaaaat
      181 tgacatgtga aaaaaaatat gatatgctgc aataaaagtt aatgtgaggt atgtcagaat
      241 gtataatgtt atagatcttt ttgcaggtgc aggtggtttg agcttaggat ttgaaatgac
      301 taaaaaattt aatatggtgg cttttgtaga aaaaaatgat aacgcagcaa aaacatacct
      361 tgaaaatcat ccgagtgtta agcgttattg tgatattaaa agattagatt ttcaagatat
      421 attaaacagt gtcgataaga tagatgttgt tataggagga ccgccatgtc aaggtttttc
      481 taatgctaat agacaaaaaa gaaaaattat aaatggaaat aatgaattag ttaagctata
      541 tgttgatgct attgataaat taaagccaaa tgtatttgta atggaaaatg tcaaaactat
      601 atcttcaaat aagcattcat tttatttgac taaaaaagat aaaaatcata taataaataa
      661 tttaaaatta aatatttata ataaagatag tgttttatat gatagaactg agtatataaa
      721 tgaattattt aatattatta gtatagaaga tattgaatca tatattatat caaatataga
      781 cttaaaaaat ttgaaaataa ttattaagaa aaaaaaggat atatgtgatt atttaaataa
      841 aatatctaat tataagaaag taaaatctac catagaaaaa ttggaaacaa ggggaaaaat
      901 gccaaaatgg tatttagaat taataaataa agtaaaaaat atattagaaa atatgttata
      961 taatagaaat ttatcagatg aacaaatatt ttatttgaac ttattcttgg atattcaaaa
     1021 tttattttta ggaatatatg agttaaaatc tgaatctgta attttcgaaa atacacttga
     1081 tgataataaa attatagcta aaatggatac ttacattata atagattata taaatgcatc
     1141 ctttgagtat ctaggatatg tattaaatgg aagtgcacta aattcaattg attatggagt
     1201 acctcaaaat agagaaagat ttgtattgat aggagcaaaa aaagacttct taaaaaataa
     1261 aaagatagaa actcctaagc ctatagttgg agaaaattat gttacagtaa gagatgcaat
     1321 aggcgattta gctgaatatg aggcttctaa aggtagtatg gattattgtt ttgaaaaaaa
     1381 tagtaataat attgaaaaag atttttatag aaagataata ttggatagca ataaaatata
     1441 caatcatgta tgtacagata caagaaatat cgcactaaaa agatttgaat atataaatca
     1501 aggaaataat tttcattctt tgccagatga gttaaaagga acttatgctg atccagaaag
     1561 aactcaaaat actatttata aaagactagt atatgataag ccatcagata ctgttgtaaa
     1621 tgtaagaaaa tctatgtgga tacatcctat taaaaacaga gctgttagcg caagagaggc
     1681 ggctagattg cagtcattcc ctgatagtta taagttttta ggtacaaaag attctgtata
     1741 tcaacagata ggaaatgcag taccaccttt attaggtcga gtagtagcag aaaagatatt
     1801 aaatttattt aatgatgaac caaatgagta tcttagagat gtgtttgaag cactagatgg
     1861 atagttcaaa taaaatagtg ggtattattc ttgtgattct tatccaacat taatccacga
     1921 aataaggact gtcgaatgag taattttaaa ttgctgtgcg acagttcttt ttttacttgc
     1981 ttttcattaa tttatattta tgcaaaattt gagcttgaaa acggtcataa gaaataaagg
     2041 tataaaaata caattttaaa atagaataat ttacaaagtg taagattaaa aaatattttt
     2101 gagaggatga atatacatac tacatttatt aatgattatc ttatttgtga aacttagaaa
     2161 tactataggc taacactaca ggtataaact ctgaaagaat attttgattg cctttgatta
     2221 gaattctttt aaagttcata ctatgtttta tttgggtgaa agctccttat gcctgaatac
     2281 ttctattcat tctaagttca catccttgtg taccagtgat tctttctaaa ttatcttaat
     2341 gccaaaatct tgttcgcatt tcaaaataaa gtcaggtagc tacttcaaca ttttagttat
     2401 atttcttcaa tagtttgtct ccaaacaaag gtacatctat tagaaacaga tttaatttta
     2461 tttatatcaa taaataatat atactttgaa acttcattaa tatcaccaag ataatttata
     2521 agttaagcta ttatatacta tcttcaccaa ctacatcctc catagtttta cactttctta
     2581 attcagcttg gtaatctaaa tctgtaataa ttatttctct ttgatttttc atttctttgc
     2641 ctacaaaagt ttaatataaa tattattcca tacttaccaa ttttacgttc aaaaaagact
     2701 gtagataagt ctgcatttac acaaacctac ttataggtct cttttttgaa attaatttag
     2761 catgaactat agtaagagca tctttaaatt catagttaca agtatacaaa gttataattt
     2821 tatctgaaat atctaccttt atatcagatt tgtgtactga tttttaggtt atataattca
     2881 aagaatattt aaactcatca ttattattaa agtgtatact taaataatct ctgttaatta
     2941 agtcagcagt atatactgaa aaaatttcat aagtataagt ttgtacttta taatttattt
     3001 ctactaagtt attttctttg aaaaatactt catcagtata gttttctagt tgaccaaaca
     3061 tagttttatt tttcatataa tgaccataga ctattaaact cttatcattt tcaaaattat
     3121 ttctataatc catgaaaata ctacctaaag gaagataatt tttataaaaa tcatgagtta
     3181 ggtagaaatc attgttatat ccttgtacta caggatagtt tatatttacg ttgtttattt
     3241 taagccagaa tctataatca ttatttttat cataaagttc ttgatgtttg ctattattga
     3301 tagtgttttc tctgagttcc gtatatactt catcagcttt tttatattca gataatttta
     3361 tgtaaatcga aaggctagag aaagttagcg caataatgca aataatattt attaatattt
     3421 ttactagttt ttcaattaat taccccttag tattattata taaaaaatta aataaatttt
     3481 atataattaa aatttttatt gtagttattt agcaaataat gaatacttat aatatataag
     3541 gttgaaaaaa acagtatatt cattgacaaa tataagtttt aagtatatat taaaaattat
     3601 tagagtgcat ataaggatgt atacagtgta tattaagaat tattagagtg tatataagga
     3661 tgtatacagt gtatattaaa aattattaag gggaggggga atttatgcaa caaaaatgta
     3721 aaaagaaagc actatcaatg attttaagta tctcaatggg acttggatca gtagcatcat
     3781 ttaatgcgtc aaatactttc gcagatacta tagaagaaag tactaatgca ggaaatgcag
     3841 aaggagatac taatgcagga aatgcagaag gagatactaa tgcaggaaat gcagaaggag
     3901 at
//
LOCUS       DAMJVG010000157         3853 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.162, whole genome shotgun sequence.
ACCESSION   DAMJVG010000157 DAMJVG010000000
VERSION     DAMJVG010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3853)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3853)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3853
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.162"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            221..1801
                     /locus_tag="PC512_003648"
     CDS             221..1801
                     /locus_tag="PC512_003648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional ADP-dependent NAD(P)H-hydrate
                     dehydratase/NAD(P)H-hydrate epimerase"
                     /protein_id="HDF2443341.1"
                     /translation="MLIGTSKLSRNVDTACVEEVGIPMIVLMENAVISAMKNMDIDMY
                     NSYTVVCGVGNNGGDGLGIARHLNTYGKEVNVFLVGNLEKLSECSKINYNVLLNMGIN
                     IININKNDLSEKNYGEENEVDKIIKVEKQNIIKNKNLTIFKDRVSKSDVVVDAIFGTG
                     LKRDITGIFKEVIDIVNDNSKNTYSIDIPSGIDSDNGNVLGTCIRANKTISFEFYKRG
                     FLNYDTSALIGDVVVEKIGVPDFITRKYHDEEFITDKTFVKNNIRRRDKHGFKSDFGK
                     VSIVAGSKGFYGASFIATESAVKSGSGLVTLISSEDVQEKVSIRLTEAMTLNFEEERL
                     NKLLNSSDAIGFGPGMGDNSQTFDKLLKIVENSNCPIVLDADGLNVMKDRCYKFLEWK
                     NRFVITPHLGEMARLTGDSIGYIREHRVDVAKEFAQKYNLVVLLKGYQTVITDGKKTY
                     INPTGNSCMATGGMGDCLLGMITSFIGQGMDILEATVSGAYIHGYIGDKLSKAMYTVN
                     ATDLISNISLTMKELLDI"
     gene            1979..2425
                     /locus_tag="PC512_003649"
     CDS             1979..2425
                     /locus_tag="PC512_003649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HDF2443342.1"
                     /translation="MKLIWLIVAVLFGIAEMLTPSLTLIWFSVGAVILIFLSSFIESI
                     FLQILIFAVISIAMLVVATKKIVKKDKGYKSNTNLQAMMSKKGIVTEEISPNNTGLVV
                     VEHETWTAISIDGEKIEKGSTVEVLKIEGVKLVVKKVDATVNVTNQ"
     gene            2446..3489
                     /locus_tag="PC512_003650"
     CDS             2446..3489
                     /locus_tag="PC512_003650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH/Band 7/PHB domain protein"
                     /protein_id="HDF2443343.1"
                     /translation="MGTKIVLSIVLIVVVVAISLTCIRVIKQSKVGIIMRLGKFQKVA
                     ETGVHFLIPFLDKMAYVIDLREIVIDFPPQPVITKDNVTMQIDTVVYYKVTDPVRYVF
                     EIANPIAAIENLTATTLRNIIGELDLDETLTSRDIINVKMRTILDEATDKWGIKVNRV
                     ELKNIMPPQDIQVAMEKQMRAERERREAILQAEGNKSAAILQAEGEKQSAILTAEAKK
                     EAMVRVAEGEKESAILVAEGEAEAIRQTAIAKAQGEAEMIKRTQMATAEGLKLVFSAM
                     KEADIDNNILALKSMEALEKMAEGKSTKLVLPSEAVNFLGTFKGIKEVMSDDNKEVLD
                     IKEVLNDNESLKK"
BASE COUNT         1566 a          351 c          708 g         1228 t
ORIGIN      
        1 taattagtgt aaataggttt taaatcaaca taataactta aattatatgg tataataaat
       61 taaataattg ttttaattca aaattttttg ttattttaaa ttatttcaaa actcttagtt
      121 ttagtgattt tatttatgat atttatggga ttaaaaagat ttcaatagat atttttggta
      181 agtatttaag aagtctttaa ctttatagga gtgataattt atgctaatag gtacatctaa
      241 attaagcaga aatgttgata ctgcatgtgt agaagaagta gggattccaa tgattgtatt
      301 gatggaaaat gcggttatat ctgcaatgaa aaatatggat atagacatgt ataatagtta
      361 tacagttgta tgtggtgttg gaaataatgg aggagatggt cttggaatag caagacatct
      421 aaatacatat ggaaaagaag taaacgtatt tttagtaggt aatcttgaaa aactaagtga
      481 atgctctaaa ataaattaca atgtactttt aaatatggga attaatatta taaatattaa
      541 taaaaatgat ttaagtgaaa aaaattatgg agaggaaaat gaagtagata aaattattaa
      601 agttgagaaa caaaatatta taaaaaataa aaatttaaca atttttaaag atagagtatc
      661 taaaagtgat gttgtagtag atgctatatt tgggactgga ttaaaacgtg atataactgg
      721 tatttttaaa gaagttattg acatagtaaa cgataatagc aaaaatacgt attctataga
      781 tattccttca ggtatagata gcgataatgg aaatgtatta ggaacttgta ttagagcaaa
      841 caaaacgatt agctttgagt tttataaaag aggttttcta aactatgaca ctagcgcact
      901 tataggtgat gtagttgtag aaaagatagg tgttccagat tttattacaa gaaaatacca
      961 tgatgaagag ttcataactg ataagacttt tgtaaaaaat aatattagaa gaagagataa
     1021 gcatggtttt aaaagtgatt ttggaaaagt atctatagtt gcaggttcaa aaggatttta
     1081 tggtgcaagt ttcatagcaa ctgaatctgc tgttaagagt gggagtggac ttgtaacatt
     1141 aattagtagt gaagatgtgc aagaaaaggt atctattaga cttacagaag caatgacttt
     1201 aaattttgaa gaagaaagat taaataaatt acttaattct agtgatgcaa ttggttttgg
     1261 tccaggtatg ggagataata gtcaaacatt tgataaatta cttaagatag tagaaaattc
     1321 taattgccca atagtattag atgcagatgg attgaacgtt atgaaggaca gatgttataa
     1381 gtttttagaa tggaaaaata gatttgtaat tacacctcat ttgggagaaa tggccaggtt
     1441 gacaggagat tcaattgggt atataagaga acatagagta gatgttgcaa aagaatttgc
     1501 tcaaaaatat aatctggtgg tgcttttaaa aggttatcaa actgtcataa cagatggtaa
     1561 aaaaacatat ataaatccta caggaaatag ctgtatggca actggtggaa tgggtgattg
     1621 tttgcttgga atgattactt catttatagg tcaaggtatg gatatattgg aagctacagt
     1681 tagtggagca tatatacatg gctatatagg agataaactg agcaaagcaa tgtatacggt
     1741 aaatgctacg gatttaataa gtaacatttc attaacaatg aaagagttgt tggatatata
     1801 attggtgata tttgatacta ctttgtaaca aatttaacaa agtatgttga tataatacta
     1861 ttaattaatt aattaattta ttttattgtt ttgtaattta aatttatatt caaaaacatt
     1921 gtataaacat ataatttata tagggtttta taattcatat gaaaagaggg tagatagtat
     1981 gaagttaata tggttgatag tagcagtctt atttggaata gcagaaatgt taacaccaag
     2041 cttaacattg atatggttta gtgtaggagc tgtaatactt atatttttaa gtagctttat
     2101 agagagtatt ttcttacaaa ttttaatatt tgcagtaatt tctatagcaa tgttagtcgt
     2161 agctactaaa aaaatagtaa aaaaagataa aggctataaa tctaacacta atttacaagc
     2221 aatgatgtct aaaaaaggta ttgttacaga agagatttct ccaaataaca caggtctagt
     2281 tgtagttgaa catgaaacat ggacggctat ttctatagat ggtgaaaaga tagaaaaagg
     2341 ttctacagta gaagtattaa aaattgaagg ggtaaaatta gttgttaaaa aagtagacgc
     2401 cacagttaat gtgacaaacc aatagaataa aggaggattt atagtatggg tactaaaatt
     2461 gttttaagta ttgtattaat agtagtagtc gtagcaataa gtttaacttg tataagagtt
     2521 ataaaacaat ctaaagtagg tataataatg agacttggta agtttcaaaa agtagctgaa
     2581 acaggtgtac atttcttaat accattttta gataaaatgg catatgtaat tgaccttaga
     2641 gaaattgtaa tagattttcc acctcaacca gttataacta aagataatgt aactatgcag
     2701 attgatacag ttgtatatta taaagttaca gacccagtta gatatgtgtt tgagatagct
     2761 aatccaatag ctgctattga aaatttaaca gctacaacac taagaaatat aattggtgaa
     2821 cttgatttag atgaaacatt aacatcaaga gatataataa atgtaaaaat gagaactatc
     2881 cttgatgaag caacagataa atggggtata aaagtaaata gagtagagtt aaaaaatata
     2941 atgcctcctc aggatattca agttgcaatg gaaaaacaaa tgagagcaga aagagaaaga
     3001 agagaggcaa tacttcaagc agaaggtaat aagtcagctg caatacttca agcagaaggt
     3061 gaaaaacaat ctgcaatatt aacagcagaa gccaaaaaag aagctatggt acgtgtagca
     3121 gaaggtgaaa aagaatctgc tatattagtg gcagaaggtg aagctgaagc tataagacag
     3181 acagctattg ctaaggcaca aggtgaagct gaaatgataa aaagaactca aatggcaaca
     3241 gcagaaggtt taaaattagt tttttcagca atgaaagagg ctgatataga caataatatt
     3301 ctagcattaa aatctatgga agctcttgaa aaaatggctg aaggtaagtc aacaaaactg
     3361 gttttacctt cagaagcagt taatttccta ggaacattca aaggaataaa ggaagttatg
     3421 agtgatgata acaaagaagt acttgatata aaagaagttt taaatgataa tgaatcatta
     3481 aaaaaataaa agagttttgt tatcatagga aggatatgga aattaaaggt cgaattaatt
     3541 aaatatagca caaaaatgca cgttgaaaag aagaggactt ataaattttt aagtcttctt
     3601 ctttgttttt attagaaaga tgaaattata aaaataaatt aacagaatct ttatacaatt
     3661 tatcctttac taatgtaaaa agtgttatat aatataatat aaaacatata gcaaataagc
     3721 atggttttag ttagtctatt tatattatta atatatattt ataaaaatat aaacattaat
     3781 actaagaaaa ctaataaata atttaaaagt ttatatcctt ttgtttaaat tatagacaaa
     3841 gaagtatcaa tta
//
LOCUS       DAMJVG010000158         3710 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.163, whole genome shotgun sequence.
ACCESSION   DAMJVG010000158 DAMJVG010000000
VERSION     DAMJVG010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3710)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3710)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3710
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.163"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            197..1816
                     /locus_tag="PC512_003651"
     CDS             197..1816
                     /locus_tag="PC512_003651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HDF2443344.1"
                     /translation="MNIVISLIGGLGLFLYGMSLMGEGLQKSAGDKLKKIIELLTSNV
                     VMGVLVGTVVTGIIQSSSATTVMVVGFVNAGIMNLSQAIGVIMGANIGTTVTAQLVSF
                     NLEGIAPIALGIGILFYLFTSNQKTKHLSEILIGFGILFTGMEFMKDAVAPLAEYKAF
                     TDALLYFSKNPVLGILAGFAITGIVQSSSASMGMLIALASQGILPLSSALPILYGDNI
                     GTCVTSLLSSVGASRNARRAAVMHLSFNVIGTIIFMLVLNKPISAIVTHFDPTDTARQ
                     IANAHTLFNLTNVIILLPFSKYIVKLANRLIPIKETESEIVNNTKYLDERMFSTPSIA
                     LGNTVQEVVRMGHKATNSLEHSIAGFLNKSNEDINKAFESEKVVNKLQKDILNYLLKL
                     SKEPLRDDEHFRTDLLFNTVNDIERVSDHAENIAELAMSVKEMNISFSDSAIREIYEI
                     YNKTITNFKDALIVLDVKDFELANKVLEVENEVNYLEKTFRNSHMIRLNNGSCTIDAG
                     VLYLDLLTNLERISDHSTNIVKQVLKLKQKI"
     gene            2190..2384
                     /locus_tag="PC512_003652"
     CDS             2190..2384
                     /locus_tag="PC512_003652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF2443345.1"
                     /translation="MINYMVEIIYSEKISEVENMLKIENIQYEFTSRDGFIFFGFYDM
                     TDAYRFETLCSDEKIRFKRI"
     gene            complement(2943..3266)
                     /locus_tag="PC512_003653"
     CDS             complement(2943..3266)
                     /locus_tag="PC512_003653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443346.1"
                     /translation="MATEIFTVKITPLEAQKMIKENLDADLVFSDSYNLGDDKFILIT
                     TFEKYYARNNSDAGLIVVYENTTGKTVIKATSTGSAIGILKIDWGAGGNLLKRVKNIL
                     ADYII"
     gene            complement(3311..3565)
                     /locus_tag="PC512_003654"
     CDS             complement(3311..3565)
                     /locus_tag="PC512_003654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443347.1"
                     /translation="MENKDFKLTICIFAFVIGVVVLFCCIGLGEFSAEHIIQQNGGIM
                     DTDQYNIYLDQSISQYRNFGSILALLGGIGILFDKYIRKY"
BASE COUNT         1361 a          477 c          455 g         1417 t
ORIGIN      
        1 aattgctata tatcataaat tttctaaaat taacaacaac ttaaaaattt aacattctct
       61 taacgtatac ttaacaaaac attaatattt ttattgacaa aatttgttat tctatattat
      121 ggaaacaata aattttagtt aataaagttt ataattcaga taaaaaaatt attaatttct
      181 taagggagga aatatcgtga atatagtaat tagccttatc ggtggacttg gactttttct
      241 ttacggaatg agtttaatgg gagaaggttt acaaaaatca gcaggagaca aattaaaaaa
      301 aattattgaa ctcttaacaa gtaatgttgt tatgggtgta ctggtaggta cagtcgttac
      361 aggtattata caaagttcaa gtgctactac tgttatggtt gtaggatttg taaatgcagg
      421 tataatgaat ctaagtcaag ctattggtgt aataatgggg gcaaatatag gtactacagt
      481 tactgctcaa ttagtttcat ttaatcttga aggaattgca ccaattgctt taggtatagg
      541 tattttattc tatttattta catcaaatca aaaaacaaag catttatctg agatacttat
      601 aggttttggt atattattta caggaatgga gtttatgaaa gatgcagtag ctccacttgc
      661 tgaatacaaa gcattcactg atgcactttt atattttagt aaaaatcctg tattaggtat
      721 attggcagga tttgccataa ctggtattgt tcaaagttca agtgcatcta tgggtatgtt
      781 aatagcacta gcttctcaag gaatacttcc tctatcatct gctttaccta ttctttatgg
      841 agataatata ggtacttgtg ttacttcact tttatcaagt gttggtgcaa gtagaaatgc
      901 tcgacgtgca gctgtaatgc atttaagttt taatgtaatt ggtacaataa tatttatgct
      961 tgttttaaat aaacctatat cagccatagt tactcatttt gacccaactg atacagctag
     1021 acaaatagca aatgcacata ctttatttaa tcttacaaat gttataatat tattaccatt
     1081 ttctaaatac atagttaaat tagcaaatag acttatacct attaaagaaa ctgaatcaga
     1141 aatagtaaat aatactaagt acttagatga aaggatgttt agcactccat ctatagcact
     1201 tggtaatact gtacaagaag ttgtaagaat gggtcataaa gctacaaact ctttggaaca
     1261 ttcaattgca ggatttttaa ataagagcaa tgaagatatt aataaagctt ttgagtcaga
     1321 aaaagttgtc aataagttac agaaagatat attgaactat ttgttaaaac tttctaaaga
     1381 acctcttaga gatgatgaac actttagaac agatttgctt tttaatactg taaatgacat
     1441 tgaaagagtc tctgaccatg cagaaaatat agctgaattg gccatgagtg ttaaggaaat
     1501 gaacattagt ttttctgata gtgcgataag agaaatatac gaaatataca ataagacaat
     1561 tactaatttt aaggatgcct taatagtttt agatgttaaa gattttgagt tagcaaataa
     1621 agttttagaa gttgaaaatg aagtaaatta tttagaaaaa acttttagaa attcacatat
     1681 gattagacta aataatggaa gttgtacaat tgatgctggt gtactttatc ttgacttact
     1741 tactaatcta gaaagaattt ctgaccactc aacaaatata gtaaaacaag tactaaaact
     1801 taaacaaaaa atatagtgat tatttttata tataatctta atcaatgaga agtaagaagc
     1861 tatagataat gcttatatca tttatggttt cttatttttt atgtaatact caaattttta
     1921 tagtattctc ttattattaa acaatttctg cctagaatat tccatatata tatgacttct
     1981 ttcataaaac ttgaactgcc cataactaaa gtcacaagta tacataacta ttttttaatc
     2041 aattataacc aatatttgtt ttatttatct tcattttaat tcttcattca ataatgtaat
     2101 aagattattt tttatttgga tactattata tcatctaaat atgttattat atatttggat
     2161 attttcatat taataggagg gattctacaa tgataaatta tatggtagaa attatatata
     2221 gcgaaaaaat aagcgaagta gaaaacatgt tgaaaattga aaatatacaa tatgaattta
     2281 cttctcgtga tggctttata ttttttggtt tttatgatat gacagacgca tatagatttg
     2341 agactttatg ttcagatgaa aaaattcgat ttaaaagaat ataatagata aaaaagtaca
     2401 tatttctaaa ctatttgttt ttcaaattta ggttgtgttt taatgtagtg ttgatattat
     2461 aaacaatttt aataataaaa aagtagggac attatattaa tatgctccta ctttttactc
     2521 atacttatta atattattta tcaaaattac cctacaaact ggaatttatc attctttcat
     2581 aattttaaac tatcatattt aaaatatata aaattccaca tgatttttgt ataaacataa
     2641 tatcaaccat tatccaattt aaaaatattt tttagtaatt tccatttcat tttctcttaa
     2701 catattaatt aaatttttat atgtaaatgg tgtatttaca tattatttaa tatccaacaa
     2761 ttatataaag aaatgtgctc tttgccttat aaagaattat aaagccaatt cgttttatta
     2821 tattattttt ctttatacct taaaaacttt accttcaaat tcttatttat ctatatatta
     2881 taaaaatgtt cttaacctct tttacgagat tttcttgaca tattatcagt tagataaaat
     2941 aattaaataa tataatcagc aagtatgttt tttactcttt taagtaaatt tccacctgca
     3001 ccccaatcaa tttttaaaat tccaattgca ctgcctgttg aagtagcttt aataactgtt
     3061 tttcctgtgg tattttcata aactactatt aatcctgcat cactattatt tcttgcataa
     3121 tacttctcaa aagttgtaat tagtataaat ttatcatctc ctaaattata agaatcacta
     3181 aaaactaaat ctgcatcaag attttctttt atcatttttt gtgcctctaa gggtgtaatt
     3241 tttacagtaa atatttctgt tgccattttt tatctcctca taagaattta ttttagacaa
     3301 aacataatct ctagtatttt ctgatatatt tatcaaacaa tatccctatt cctcctaaca
     3361 gagctaatat agaaccaaaa tttctatatt gagaaataga ttggtctaga taaatattat
     3421 attggtcagt atccatgatt ccaccatttt gttgaataat atgctctgca ctaaattcac
     3481 ctaaacctat acaacagaat aatactacta ctccaattac aaaagcaaat atacatattg
     3541 ttaatttaaa atccttattt tccatagtta tccctctcat aagctaaatt tatttgatta
     3601 tttttactag attttatatt actcttatta tacaatacaa catatattta catctatttc
     3661 caaaattgta acctttatag ttttatatat ttaaattttt taaacaaaaa
//
LOCUS       DAMJVG010000159         3699 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.164, whole genome shotgun sequence.
ACCESSION   DAMJVG010000159 DAMJVG010000000
VERSION     DAMJVG010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3699)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3699)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3699
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.164"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            301..1677
                     /locus_tag="PC512_003655"
     CDS             301..1677
                     /locus_tag="PC512_003655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HDF2443348.1"
                     /translation="MKTIVRRLILYADGMRPTQIMVSGFAAIIVIGALLLTLPIASQS
                     GESIGLLNALFTATSAVCVTGLVMVDTATYWSLFGQIVIITLIQIGGLGFMTVATMFS
                     LMARKKIQLRERLLIQESLNQADLSGLVRLTRFVLIITITIEGIGALVLSTVFIPQFG
                     LSKGIWYSVFHAISAFCNAGFDLMGSVSGPFTSLNSYVNNFTVSMTVCALIVLGGLGF
                     PVVLDIVRKRRFSKLNVHSKVVLFSTATLIFVGALFIFLIEFNQKATMADLPLKGKVL
                     SAIFQSVTARTAGFNTLDLATLRESSVFVMIILMFIGASPASTGGGIKTTTLAVLIIT
                     VRSFLSGKSDIEAFERRLAPSTIKKSLGIFVISISAVIFGTLIISITQPNFTLVQSAF
                     EVTSALATVGSSLAGTPNLNALGKIIIIIFMFMGRVGSLTLFMAILSGGRRKSQPIRY
                     AEGKIMVG"
     gene            1964..2635
                     /locus_tag="PC512_003656"
     CDS             1964..2635
                     /locus_tag="PC512_003656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HDF2443349.1"
                     /translation="MKQYIVIGCGRFGSSVASTMHLLGHQVMAIDKNEDSVQSISDKV
                     THSLIVDVTDEQALRSLGLGNFDVAVVAIGSDIRASIMATLIAKEMGVELIICKAKDE
                     LQAKVLYKIGADRVVFPERDMGVRVAHNLVSDNILDHIELDPEYSIVEIVTPNSWVGK
                     TLIELELRARYEITVLAIKTGKNINVTPSPDEELTAGSILVIIGQNTSITAITSGNKG
                     IIRRR"
     gene            2824..3621
                     /locus_tag="PC512_003657"
     CDS             2824..3621
                     /locus_tag="PC512_003657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HDF2443350.1"
                     /translation="MITNINSKDNEKLKYTRALLKSKNRNKESKFIIEGYRIVMLALE
                     CMANLDYVFINEEFENKKEHVKLLEDLDKKNTKIYKTTNKNFKELVDTENTQGIIGVV
                     SFKKKKLSESINKKDKFVLILDRIQDPGNMGTIIRTADSAGVDAIIALKGCVDIYNPK
                     VIRSTMGSIFDVNIIDASQDETVDMLKSLDFNIVSSYLNTENFYDKIDYGSKVALVIG
                     NEANGINEELVSKSDILVKIPIYGKAESLNAAISSAILMYEIKKYLI"
BASE COUNT         1409 a          411 c          682 g         1197 t
ORIGIN      
        1 aaaagtatat gaaatttata ctggtaaaat gataaataaa ttttaagtac aaaatagtaa
       61 aagctatgat agttttagac ctattatatg taaaaaatat agatgttttt ggtgcaattt
      121 aaattaaaag atatatataa aaatttaaaa tattccaaac agaaattata aaaattacta
      181 tcattgtctt tatacaatat ttatactata atagaataat aatttagagg aaagctctaa
      241 aaataaacaa attaagggtc ttaacagtag tgattttatg ttaaggaggt ataaagaaag
      301 ttgaaaacaa tagttagaag acttattctc tacgcagatg gaatgcgtcc tactcaaata
      361 atggtatctg ggtttgctgc gattattgta atcggagcat tgttgttaac actcccgata
      421 gcgtcgcaga gtggagagag tataggctta ttaaatgctc tatttacggc tacttcagcg
      481 gtttgtgtta ctggtctagt tatggtagat acagcaactt attggagttt atttggacag
      541 atagttataa taacattgat acaaattggt ggtcttggat ttatgaccgt agccacaatg
      601 ttttcactta tggcacgaaa aaaaatacaa ctaagagaaa gattattaat acaagagtca
      661 ttaaatcaag ctgatttatc gggacttgta agacttacaa gatttgtatt aataataacc
      721 ataacaatag agggaatagg tgcactggtt ttatcaactg tctttattcc acaatttggt
      781 ttgtctaaag ggatatggta tagtgtattt cacgcaatat cagcgttttg taatgccgga
      841 tttgacttga tgggcagtgt aagtggccca tttacatcgt taaattctta tgtaaacaac
      901 tttacagtat caatgactgt ttgcgcactt atagtgcttg gagggctagg attccctgtt
      961 gtacttgata ttgtaagaaa aagaagattt tcaaaattaa atgtgcattc taaggttgta
     1021 ttgttttcaa ctgctacact tatttttgtg ggtgcattat ttatttttct tatagaattt
     1081 aatcaaaaag ctactatggc ggacttgcct ttaaagggaa aagtactatc agcaatattt
     1141 caatcagtaa cagcaagaac tgctggtttt aatacgcttg atttagctac tttacgagaa
     1201 agtagtgtat ttgtaatgat aattttgatg tttattggag catcacctgc atcaactggt
     1261 gggggtataa aaacaacaac actagctgtt ttaatcatta cagttagaag ttttctatca
     1321 ggaaaatcag atatagaagc ttttgaaaga agattagctc catcaactat aaaaaaatct
     1381 cttggtatat ttgtaatcag tatatcagca gttatttttg gaacattgat tatttcaata
     1441 actcagccta attttacatt agttcaatca gcttttgagg ttacatcagc acttgctaca
     1501 gttggttcaa gtttagctgg aactccaaac ttaaatgctt taggtaagat tataataata
     1561 atctttatgt ttatgggtag agttggttct cttactttat ttatggctat actttctggt
     1621 ggtagaagaa agagtcaacc aatcagatat gcagaaggta aaattatggt tggttaagtt
     1681 accaaggagt aatataaatt tataatggat ttagagtagc actgtaaatc tgttgataaa
     1741 ataaatgagc ctagatgtaa ttatatgaag aaataaaatc gactaacgaa caaaattaat
     1801 taatgaaata aaaaaacagg gaaataaaat acaaataaaa aggtaaatca aaattaaatt
     1861 aatctgtgta tataaaatta tatattgtgt ataagttttg tatgtgtaaa caattaattt
     1921 aagagatatt atataaattg tgtattaggg aggaagtttc gagatgaagc aatatatagt
     1981 cattgggtgt gggagatttg gaagttcagt tgcgtctact atgcatcttt taggacatca
     2041 agtaatggca atagacaaaa atgaagattc agttcaaagt atatctgaca aggtaaccca
     2101 ttcacttata gtggatgtta ctgatgagca agcgttaagg tcattaggtt taggtaactt
     2161 tgatgtagca gtagttgcaa taggttctga tataagggca tctataatgg cgactcttat
     2221 agccaaagaa atgggtgtag agttgataat atgtaaggca aaggatgaat tacaagctaa
     2281 agtgctttat aaaattggcg cagatagagt tgtatttcca gaaagagata tgggagtaag
     2341 agttgcacac aatttagttt cagataatat attagaccat attgaacttg acccagagta
     2401 ttcaattgtt gaaatcgtaa ctccaaatag ttgggttggc aagacactta tagagcttga
     2461 attaagagct agatatgaga taactgtact tgctataaaa acaggtaaaa atataaatgt
     2521 tacaccttct ccagatgagg aacttacagc cggaagtatc ctagttataa tcggtcaaaa
     2581 tactagtata acagcgataa catctggaaa taaggggata attagaagaa gataatttac
     2641 tatttaatat atatttaatt gcaatgaaag tagatagtat catataatta tgaatagtta
     2701 tatgatacta tttttttaat cgaaggtagt atttatttgt aagattagat aaagagaaat
     2761 taaattaaaa gtaaggaggc tgtgctaata taaaaattta taagttatta gcatttagat
     2821 aaaatgatta caaatataaa cagtaaggat aatgaaaagt taaagtatac aagagcacta
     2881 ttaaaatcaa agaataggaa taaagagtca aagttcataa tagagggata cagaatagta
     2941 atgcttgcac ttgaatgtat ggcaaacctt gattatgtat ttatcaatga agaatttgaa
     3001 aataagaaag aacatgtaaa actattagaa gatttggata aaaaaaacac aaagatatac
     3061 aagactacta ataaaaactt taaagaatta gtggatacag aaaatactca aggaataata
     3121 ggtgtagttt catttaagaa aaaaaaatta agtgaaagta taaataaaaa agataaattt
     3181 gtattgattt tagacagaat acaagaccca ggaaatatgg ggactataat aaggactgct
     3241 gattctgctg gagtagatgc cataatagca ctaaagggat gtgtcgatat atacaaccca
     3301 aaagtaatta ggtctactat gggttctatt tttgatgtga atataattga tgcttcacaa
     3361 gatgaaactg tggacatgct taaatcattg gattttaata tagtttcaag ttacttaaat
     3421 acagaaaatt tttatgacaa aatagattat ggctcaaaag tagcattggt gataggaaac
     3481 gaagcaaatg gaataaatga agaacttgta tcaaagtctg atattttggt taagatacct
     3541 atatatggta aagccgagtc gttaaatgct gcgataagct ctgctatact gatgtatgaa
     3601 ataaaaaaat acttaattta atgtattgta ataaatataa tgtcatgtta taatcttgaa
     3661 ttaaatagta gagtatcaaa aatagtcaat atatattaa
//
LOCUS       DAMJVG010000160         3686 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.165, whole genome shotgun sequence.
ACCESSION   DAMJVG010000160 DAMJVG010000000
VERSION     DAMJVG010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3686)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3686)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3686
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.165"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            261..620
                     /locus_tag="PC512_003658"
     CDS             261..620
                     /locus_tag="PC512_003658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002583503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2443351.1"
                     /translation="MKLRESYTCPLELVHDIIKGKWKTIIIFQLRNGKCSFSELHHSI
                     AGITQKMLLEQLRELKHFGLIDKKTYDGYPLKVEYFLTGQGEKMLSAIKIMQEIGIDY
                     MVEHGMTEILDEKGICY"
     gene            710..1261
                     /locus_tag="PC512_003659"
     CDS             710..1261
                     /locus_tag="PC512_003659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HDF2443352.1"
                     /translation="MKKALLIIDVQNDYFPNGKCQLYKPEIALNTIKDLLKIFRKQNL
                     PIIYIRHESIHGTFFNPNTNGVQIHNDIKPLDTETVIVKHYPNSFYETNLQNKLVEIE
                     VTKLVVCGMMTHMCIDTTIRAAKDYGYEITLISNGCATKELKWNGVNIPADTVQSIFM
                     ASLNQKFANVITSTEFLSNEITR"
     gene            1245..1610
                     /locus_tag="PC512_003660"
     CDS             1245..1610
                     /locus_tag="PC512_003660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009291267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2443353.1"
                     /translation="MKLRDEYTCPLELIHDMIKGKWKPIILWRLRLGATSLSKLENDI
                     DGITQKMLLEHLKELIDYGFVDKKTFSGYPLHVEYFLTEDMGNQILEALRIMQHIGIE
                     YLRKNGMENELTEKHVIPD"
     gene            1698..2198
                     /locus_tag="PC512_003661"
     CDS             1698..2198
                     /locus_tag="PC512_003661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015393784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhB/YbcL family Raf kinase inhibitor-like
                     protein"
                     /protein_id="HDF2443354.1"
                     /translation="MYISSIGISNGIIEKKYGSHGVQFNENDVPTYSIPFKIENAPDK
                     TVSFAFILEDKDAYPVTGFIWVHWLGANLTRSELKENESQTAKDFIQGANSWTSILGN
                     QQTREQTSCYGGMAPPDKAHIYELHVFALDKLLDLKNGFYLNELYQEMEGHILEEAVL
                     KGLYEK"
     gene            2188..2703
                     /locus_tag="PC512_003662"
     CDS             2188..2703
                     /locus_tag="PC512_003662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016285890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDF2443355.1"
                     /translation="MKSKPVKVGLRTIKTVLSAFLCFLIDSLRASSVPFYAVIASILC
                     IQPDMENSLSVAKNRELSTIIGGILGMLFLLMERIFLPIQPEILRELTLSILLIPIIN
                     LSVLLKQKKGTFLTCVVFLCVTVTHEKDISPIWFAWNRIVDTSLGIGISLAVNSFPFH
                     KFKVGGTMGKY"
     gene            2697..2978
                     /locus_tag="PC512_003663"
     CDS             2697..2978
                     /locus_tag="PC512_003663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDF2443356.1"
                     /translation="MLIVEFTEKEDAVFQQAVEWLSSKLAYTPASFNQQKKGFDIDPL
                     TRTFTNEEGTSIYLTAKEFDLLYFLSSHKGQVFTKEQIYEKVWGYDNFY"
     gene            3132..3322
                     /locus_tag="PC512_003664"
                     /pseudo
     CDS             3132..3322
                     /locus_tag="PC512_003664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003064779.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4177 domain-containing protein"
     gene            3346..3570
                     /locus_tag="PC512_003665"
     CDS             3346..3570
                     /locus_tag="PC512_003665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008393106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443357.1"
                     /translation="MIGIKKRDIKKALKAGAKAGGSSYADVLADIEATIDEVMNSTDP
                     EVQANFKKYFGNKRPTPEEYIYKITKKTRV"
     gene            3592..>3686
                     /locus_tag="PC512_003666"
     CDS             3592..>3686
                     /locus_tag="PC512_003666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006863419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDF2443358.1"
                     /translation="MKNEMWVLCPICNNKTRTKVREDTELINFPL"
BASE COUNT         1329 a          501 c          721 g         1135 t
ORIGIN      
        1 ttccccatag aataccttat cgcctaaatc attacgagaa agcccagctt tttcacgggc
       61 ttctctgatt gccagcccta gcggtctgaa atcaaaagta tgtgtttctt ttgtttttct
      121 cattttaaat caccatacat gagtttatac ttcatggttc gtatttagaa tgtgttaaaa
      181 gtgcatatat tagggtaata aaatatgttt tgaaatattg agcttaaaca tgtaagatat
      241 ttcacatagg agatgataaa atgaaactta gagaaagcta tacatgtcca ttagaacttg
      301 ttcatgatat tataaaggga aaatggaaaa cgataattat ttttcaactt agaaatggaa
      361 aatgctcttt ttccgaactc catcacagta tagcaggaat tactcaaaaa atgctattgg
      421 aacaactgcg tgaattaaaa cactttggct taattgataa aaaaacatat gatggatatc
      481 ctctaaaagt agaatacttt ttaactggac agggagaaaa gatgctatca gcaattaaga
      541 taatgcaaga aattggtata gattacatgg tagagcatgg tatgacagaa atccttgatg
      601 aaaaaggaat ttgttattaa actctatcat atacacgaaa aagtaagtaa tttacttaga
      661 aactattatc ttatattatt taattagaat taagagagga tatgagagta tgaaaaaagc
      721 attacttatt attgatgtgc agaatgatta ttttcctaat ggaaagtgcc agttgtataa
      781 accagagatt gcgttgaata caataaaaga tttattgaaa atttttagaa agcaaaactt
      841 gccaattatt tacattcgcc atgagtctat ccatggaaca ttttttaatc caaatacaaa
      901 tggtgtacaa atccataatg atattaaacc attagataca gaaacagtta ttgttaaaca
      961 ttatccaaat agtttttatg aaacgaattt gcaaaacaaa ctggtagaga ttgaggtaac
     1021 gaaattggtt gtttgtggaa tgatgacaca tatgtgtatt gacacaacta taagagctgc
     1081 caaagattat ggctatgaga ttacactaat atcaaatggt tgtgcgacca aggaattaaa
     1141 atggaatgga gtcaatatcc cagcagatac agttcaaagc atatttatgg cttctttaaa
     1201 tcagaaattt gctaatgtta ttacaagcac ggagtttttg tcaaatgaaa ttacgagatg
     1261 aatatacatg tcctttggaa ttaattcatg atatgataaa gggaaaatgg aagccaatta
     1321 ttttatggcg cttacgatta ggtgctactt cattatctaa attagagaat gatattgatg
     1381 gaattacaca aaaaatgctt ttggaacatt taaaggaact tatagattat ggatttgttg
     1441 ataaaaaaac attttctggt tatccacttc atgtcgagta ttttttgacg gaagatatgg
     1501 gaaatcaaat actagaagca ttacgaatta tgcaacatat agggattgaa tatttaagga
     1561 aaaatggaat ggaaaatgaa ttaactgaga aacacgtgat tccagactaa tacctacaaa
     1621 aaagtgggta atttacgttt tgcttcctct ttgttaatat atatctgtaa ttaaacgata
     1681 tacaaggagg aaaatttatg tatatttcaa gtataggaat ttctaatgga attattgaaa
     1741 aaaaatatgg tagtcatgga gtgcaattca atgaaaatga tgtgccaacg tattcaattc
     1801 cgttcaaaat tgaaaatgca ccagataaaa cggtttcctt tgcctttata ctggaagata
     1861 aagacgcata tccagtgacg ggttttatat gggtgcattg gttaggagct aatctaacaa
     1921 gaagtgaatt aaaggaaaac gaaagccaga cagcaaagga ctttatacaa ggtgcgaata
     1981 gctggacaag catattgggg aatcagcaaa ccagagaaca gacaagctgt tatggtggaa
     2041 tggcaccacc agataaagca catatttatg agcttcatgt atttgccctt gataaactgc
     2101 ttgatttaaa aaacggattt tatcttaatg aactctatca agaaatggag gggcacatcc
     2161 ttgaagaagc tgtactaaaa gggttgtatg aaaagtaagc ctgttaaagt tggattgcgg
     2221 acaattaaga cggtactttc tgcgttcctt tgttttttga tagatagctt aagagcttca
     2281 agtgttcctt tttatgcagt gattgcgtct atactgtgca tacagccaga tatggaaaac
     2341 agtttgagcg ttgctaaaaa cagggaactt tcaacaatta tcggcggtat actgggaatg
     2401 ctctttttgc ttatggaaag aatttttttg cccattcagc cagaaatact tcgggaattg
     2461 actttatcta ttttattgat tccaatcatc aatctgtctg tactgttgaa acagaaaaaa
     2521 ggaacatttt taacgtgcgt tgtattctta tgcgtaacag taacacatga gaaagatata
     2581 agtcctattt ggttcgcatg gaataggatt gttgacactt cattagggat tggtatttca
     2641 ctggcagtaa actctttccc ctttcataaa tttaaggtag gtggtactat gggaaaatac
     2701 tgattgttga atttactgaa aaagaggacg ctgttttcca acaagcggtg gaatggctgt
     2761 cctctaaact tgcttacacc cctgcttctt ttaatcagca gaaaaaagga tttgatatag
     2821 acccattaac ccgtaccttt accaacgaag agggaacgtc tatatatctg actgctaaag
     2881 aatttgacct actatatttc ctttccagcc acaaaggaca ggtgttcaca aaagaacaga
     2941 tttatgaaaa ggtatgggga tatgacaatt tttattagtc tggcaataat gaagaaaaaa
     3001 gaattttaga aaagtgaggt gtgcttatgg atttatctat tttggtagta gtattgatat
     3061 tgggtgtggg tattccttta agaaataagg caatcaaaaa atacagataa aatatgaaaa
     3121 agaaaggaaa aatgaaaaaa tatgaatatt tagaaattga ttatactgcg aaaggtgttg
     3181 tattcctttg caccgataaa cataaggaag ttataaatag ctatgcagaa aatgggtatc
     3241 gctatgcggg ttcgtgccta cagaaattga cgcaaaaggc tgtatgcgaa agatagattt
     3301 aatttttgaa aaagaagatt aacgtatttt agggagttgg ttcttgtgat aggaattaaa
     3361 aaacgagata ttaaaaaagc attgaaagct ggtgcaaagg ctggtggttc ttcgtatgct
     3421 gatgttttgg ctgatattga agcaacgatt gatgaagtta tgaacagcac cgacccagaa
     3481 gtgcaggcaa atttcaaaaa gtattttgga aataaacgcc ctacaccaga ggaatatatc
     3541 tataaaatca cgaagaaaac acgagtttaa agaattagta agggtggttc tgtgaaaaat
     3601 gaaatgtggg tattatgtcc tatttgcaat aataagacac gaactaaagt gcgagaagat
     3661 acggaattga taaattttcc tttgtt
//
LOCUS       DAMJVG010000161         3456 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.166, whole genome shotgun sequence.
ACCESSION   DAMJVG010000161 DAMJVG010000000
VERSION     DAMJVG010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3456
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.166"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(112..1679)
                     /locus_tag="PC512_003667"
                     /pseudo
     CDS             complement(112..1679)
                     /locus_tag="PC512_003667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021426623.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iota toxin protein Ib"
     gene            complement(1654..1797)
                     /locus_tag="PC512_003668"
     CDS             complement(1654..1797)
                     /locus_tag="PC512_003668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443359.1"
                     /translation="MYVYYFESPEKFAFNKVIRTKNQNEISLEKFNEFKETIQDKLLP
                     YNR"
     gene            complement(2015..2197)
                     /locus_tag="PC512_003669"
     CDS             complement(2015..2197)
                     /locus_tag="PC512_003669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443360.1"
                     /translation="MKKFRKHKSISNCISILLILYLTLGSLLPNNIYAQDLQSYSGKV
                     CNTTYKAPIERSEGFF"
     gene            complement(2586..3332)
                     /gene="cdtR"
                     /locus_tag="PC512_003670"
     CDS             complement(2586..3332)
                     /gene="cdtR"
                     /locus_tag="PC512_003670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family response regulator CdtR"
                     /protein_id="HDF2443361.1"
                     /translation="MDILIFDNDVCFGMKLKEKINNILIKEGFDNDVVRLYHNANLLL
                     KELTEKNKVRIYFIVVDAKYKISNELCDGLWIAQKIRESDYISPIIFLTNHIEMILGI
                     FDYRLEVMDFILKHDMEIAESKIKACIKIAHKRYIKEKNYRSNFFTIYSDFSLWKISF
                     DEVIYFETSTIPHKIKLVTTSRIFEFYKSLKSLPDLDACFIRVHKSFVVNKYHIVSLD
                     LKKNNIKMSNGHICRISNTYRNILKNIIKT"
BASE COUNT         1150 a          451 c          378 g         1477 t
ORIGIN      
        1 tattagaaga agataatatt taaataaaaa ataccttata aagttaattt tttaatactt
       61 tataaggtaa atacatattg tattgtgggg ataaatttaa atcatttgat actaatcaac
      121 actaagaacc aataactctc tatcatcttg agtaattgta tatattctta atttcttgta
      181 tgtcataata ttttctccac ctgtaaaata actcctaaga ttaacacaat cagttttagg
      241 ttgatttgta tctcctaaat aattacgcaa ttctttatct ttagtttcaa tatctttaaa
      301 tccaaaatat tgtaaagtag cttcaactct atatttttgg acataatcga gagcttcttt
      361 attagtttat gttggtgtaa aatacatacc atttatataa gcctttattg tacttggatt
      421 aaatttaaaa tctgcagaat atattttatg tgtaactatt atttcttgaa cagttggaat
      481 tttaacttct ggttcatcaa gtatttcagg agtactattt agctctgtaa tagataagtt
      541 atctaagtat attgtatcac tatcaattaa tgctatattt atattagaag aatctttttc
      601 agtagtttca aattcataac taaattttgt atatccttgt tctagtacca aataatccgt
      661 tttttcttct tttactttta tatttacaat tattgaatta tatgttaaag gattttttga
      721 attttactaa aaacataacg tttataaggt tttagttcag acataggtat tttaatcttc
      781 gtctcaccat ttaatctatt tgctgagcct tttaaaccat cttgatttgt agtattaaca
      841 ttactccata tactagggta attattgtaa tcatcaaaat tagtaaagta agttggtgtt
      901 tttataagta tattcattcc tctttcaagt ttaacattac atatttgttt atcagacaaa
      961 gtttttaaac tgtctttaat cttattgcct atattatcat caaatatgag ttcaacacaa
     1021 ctttcatcta ttggtatatt attaaaatat aacaaaccat cttttttagt agtgccaaaa
     1081 gttttttcaa ttgcttctcc aattgtaagt tcaggtgttt tatcttctgg gacctgtaaa
     1141 cttttagcag taattcttct tttgtaagat tcattttctg tatctaatat aatagataca
     1201 gaaatactgt caatttgacc tatatcgtct taccaactat ttcattctgt tactatttgt
     1261 ccagaaccat tttttgtacc aaaatttcca cttacttgtg ttgtttctaa tttaatttgc
     1321 tttccatcat ctaatttttt taattaatta taatttatag gaatcagtct agaactaaat
     1381 tgatacattg tgttaagagc cataggtgaa aatccttttt tgagataagt atttccagga
     1441 gatagattat tgccaatttg attttcttgt gctttgatag ttgataatgc atctccatct
     1501 aacactaaat ttgttgttgg tgtcactttg tacataggtg cagtacctgt gttgtagtat
     1561 ctaatatttg catttatata tgcagattct cctttgttta tacttaatcc agtatttcat
     1621 gattatccat tgctattttg aacagcagtt gaattatctg ttgtatggta ataatttgtc
     1681 ttgtatagtt tctttaaact cattaaattt ttctaatgaa atttcgtttt gattttttgt
     1741 tcttattact ttattaaatg caaatttttc tggagattca aaataatata catacatagg
     1801 tttatctatt ttattttttg atatagcatt tcgaagttct ctatattctt tttctcaaga
     1861 atttgcttct atttgataat cataaaaata atttcttgtc tgagaatatt tgcttatctc
     1921 tatagaatct tttttatatg atcctaatac ttctttttca gatttttcaa gtttttgatc
     1981 ttttctttct cattctttag ccttttcttt atctttaaaa aaatccttct gatctttcta
     2041 taggagcctt gtaagtagta ttacaaactt ttccactata gctttgtaaa tcttgtgcat
     2101 aaatgttatt aggtaacaaa ctacctaaag ttagatataa tatcaacaat atagatatac
     2161 aattactaat acttttatgt ttcctaaatt ttttcattta ttctccctac aaatattagt
     2221 ttagttaact tttgaatttt aatttattta gattatataa tctaaataag aattttttat
     2281 ataaatttca taaaatatgt aggtatatat cataaaaata tgtatttata tgatatgtca
     2341 gtacaaaata acaactgaat attttaaaga gactatttcg tacttttatg atttaatgag
     2401 ctatcttatc gaatcataat ctaggaacaa ttgttataat atctaatagt agttatatat
     2461 gatatagtca gtatgtgttt tttcacaata tgattattat atagaggatt cttagggatt
     2521 actctttttg tataaaaaag agatggttca aatttttatc ttgagacatc tcctttttct
     2581 atttattatg ttttaataat attctttaaa atatttctat atgtattaga tatacgacat
     2641 atatggccat tactcatttt aatattattt ttctttaggt cgagagaaac aatatgatat
     2701 ttattaacta caaaagattt atgtacacgg ataaagcatg catctaaatc tggtaaagac
     2761 tttaaacttt tatagaattc aaatattcta gaagtagtca ctaattttat tttatgtgga
     2821 atagtgcttg tttcaaaata tataacttca tcaaatgaaa ttttccatag tgagaaatct
     2881 gaatagatag taaaaaaatt agagcgataa tttttttctt taatgtatct tttgtgagca
     2941 attttaatac aagcttttat tttactttca gcaatttcca tatcatgttt tagtataaag
     3001 tccataactt ctaacctata atcgaagatc cctaaaatca tttctatatg atttgtaaga
     3061 aatatgattg gactaatata atctgattct ctaatttttt gtgctatcca taatccatca
     3121 cataattcat tacttatctt atattttgcg tctacaacta taaaatatat tcttacttta
     3181 tttttttcag taagctcttt taataacaaa tttgcattat gatataatct tacaacatca
     3241 ttatcaaaac cttcttttat taaaatatta tttatttttt cttttagttt cattccaaaa
     3301 caaacatcat tatcaaagat taatatatcc actaaatacc ctcctataaa aaattcaaaa
     3361 gtaaaaaaac aaaagtattt tatagaaaat acataaaata acactaggag ataaataaga
     3421 ttaaggatag ttagaattaa ggtatattta tgcttg
//
LOCUS       DAMJVG010000162         3448 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.167, whole genome shotgun sequence.
ACCESSION   DAMJVG010000162 DAMJVG010000000
VERSION     DAMJVG010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3448)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3448)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3448
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.167"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            2..1075
                     /locus_tag="PC512_003671"
     CDS             2..1075
                     /locus_tag="PC512_003671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HDF2443362.1"
                     /translation="MNKFKLKRSILISLIILIFIFIVYFVSIELKDRSLVNNQYKGKI
                     KSANLSVDYEINQVMKDIDKLGLNTVNVPIIINVESINSDIMSIDNNSKEKAIKLIKK
                     LNKKGISTILEAYPWIENGKLYETDWNPINKKRFFYTWQNAILNELIIDVANPLDVNV
                     LNIGSNFVHLEEYQQNWGEIIDFVQSKFDGFVTYRTNWWYTKKDDLSSKLFYEQKLNN
                     NFFDKLDFISIAAYFELSNKPVNTVDELISALHSSTVNNRGQNIKQEIYNLYKAHRKP
                     IFFGELGFSNRESASSQPWNHTPSKAVNGEEQARCFEAYKKVFENEDWINGFSVFCVG
                     KIDDEKNFYPSKESIKVIKSWYE"
     gene            1129..2253
                     /gene="wecB"
                     /locus_tag="PC512_003672"
     CDS             1129..2253
                     /gene="wecB"
                     /locus_tag="PC512_003672"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (non-hydrolyzing)"
                     /protein_id="HDF2443363.1"
                     /translation="MNDIKVMTVFGTRPEAIKVAPLIKELEKRENIKSIVCVTAQHRE
                     MLDQVIETFNINVDYDLDIMEKGQSLNDITCKILNKLPLILNKENPNIILVHGDTTTT
                     LATSLTAFYNKTLVGHIEAGLRTYDKYSPFPEELNRQLTGIIADMHFAPTNLARKNLI
                     SEGKPNNNIFVTGNTAIDALKMTIKENYNHPIIDEIGNDRMILLTSHRRENLGKPMKN
                     IFRAIKRIVDDFEDVQIVYPIHLNPKIRTIADEIFGKFPEKIHIIEPLDVADFHNFLN
                     KSYMIMTDSGGMQEEAPSLGKPVLVLRDKTERTEGIEAKTLKLVGTNEDRIYNSVSDL
                     LINKDNYVQMSKASNPYGDGNASKYIVDIIIKKFNCKYLN"
     gene            2331..3305
                     /locus_tag="PC512_003673"
     CDS             2331..3305
                     /locus_tag="PC512_003673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HDF2443364.1"
                     /translation="MARKLIKNLGKSKSVKRVKLLFKKIFITVFIVASIVAIFNITKY
                     FEELYKVRDLKSTKIEYYMDVADEAGDGKVQLSWKALLAIDMVIHDEDLSNIKKKDTL
                     DIGEKFIVEDKNDKGEKVYKVKKFNKVLSELKFDSSQKSRARKYMKDLEYTYLGNKQL
                     DSSDEKIKFIKKLEDSAIREYIDYGILPSITIGQAILESGWGNSKLTKQSNNLFGIKA
                     DKAWKGKSVEISTSEHYNEKIVASFRSYNSLQDSVKDHSLFLINNKRYRKHGLFEAKD
                     YISQAQSLENAGYSTAEDKKGNRIYAELLIDVIRSYNLQLIDNKVETK"
BASE COUNT         1444 a          336 c          598 g         1070 t
ORIGIN      
        1 tatgaataaa tttaaattaa aaagaagtat tttaatctca ttaataatct taatttttat
       61 atttatagtt tactttgtaa gtattgagtt aaaagatagg agtctagtaa ataatcaata
      121 taaaggtaag attaaatcgg ccaatttatc tgtagattat gaaataaatc aagttatgaa
      181 ggatatagat aaattgggat tgaatacagt aaatgtacct ataattataa atgtagagtc
      241 cattaattct gatattatgt caatagataa taatagtaaa gaaaaggcaa ttaagttaat
      301 aaaaaaatta aataaaaaag gtatttcaac aatattagag gcatatccat ggattgaaaa
      361 tggaaaattg tatgagactg actggaaccc tataaataaa aaaagatttt tttatacttg
      421 gcaaaatgcc atattaaatg aacttataat tgatgtagca aatccactgg atgtaaatgt
      481 tttaaatatt ggttctaatt ttgtacattt ggaagaatat caacaaaatt ggggtgaaat
      541 aatagatttt gtacaatcca aatttgacgg ttttgtaacg tacagaacta attggtggta
      601 tacaaaaaaa gatgatttaa gtagtaagtt gttttatgaa caaaagctga acaataattt
      661 ttttgataag ttagatttta tatctatagc agcatatttt gagttaagta ataaacctgt
      721 taatacagtg gatgaattaa tttctgcctt acactcatct actgtaaaca atagaggaca
      781 aaatataaaa caagaaatat ataaccttta taaagctcat agaaaaccta tattttttgg
      841 agaattaggt ttttcaaata gagaaagtgc aagttctcag ccgtggaatc atactccttc
      901 aaaagctgta aatggcgaag aacaagcaag gtgttttgag gcatataaga aagtttttga
      961 aaatgaagac tggataaatg gtttttctgt gttttgtgta ggtaaaatag atgacgaaaa
     1021 aaatttttac ccatcaaaag agagtataaa agttattaag tcttggtatg aataattttg
     1081 aaagtgtaga atttatatag attaaataga tgattaggag agacataaat gaatgacatc
     1141 aaggttatga ctgtatttgg aactagacct gaagctatca aagtagcacc tttaataaag
     1201 gaacttgaaa aaagagagaa tataaaaagt attgtttgcg ttacagctca acatagagaa
     1261 atgcttgacc aagttataga aacctttaat ataaatgtag actatgattt ggatataatg
     1321 gaaaaaggac aaagcctgaa tgatataaca tgtaagattt taaataaact tcccttgatt
     1381 ttaaacaagg aaaatccaaa tataatattg gtacatggag atacaaccac aactctagct
     1441 acaagtttga ctgcatttta taataaaact cttgttggtc atatagaagc tgggcttaga
     1501 acctatgata aatattctcc ttttccagag gagttaaata gacaacttac aggtattatt
     1561 gctgatatgc actttgctcc tactaatttg gctagaaaaa acttgatttc tgaaggaaaa
     1621 cctaataata atatatttgt aactggtaat actgctattg atgctttaaa gatgacaata
     1681 aaagaaaact ataatcatcc tataattgat gagattggta acgataggat gattttacta
     1741 acctctcaca gaagagaaaa tttgggtaaa cctatgaaaa atatatttag agctataaag
     1801 cgaatagtag atgactttga agatgtacag atagtatatc ccatacattt aaatcctaaa
     1861 atacgaacta tagctgatga gatatttgga aaatttcctg aaaaaattca tattatagag
     1921 cctttagatg tagctgattt tcataacttt ttaaataaat cttatatgat aatgactgat
     1981 agtggaggaa tgcaggaaga agctccatca ttaggtaagc cagtccttgt gttgcgtgat
     2041 aaaacagaaa gaacagaagg aattgaagca aagacactta aattagtagg tactaatgaa
     2101 gatagaatat ataattcagt gagcgattta ttaataaata aagataacta tgttcagatg
     2161 agtaaagcat ctaatccata tggagatgga aatgcaagca aatatatagt ggatataata
     2221 attaaaaaat ttaattgcaa atatttaaat tagataagac ctaaaacatt aactaattga
     2281 tataagattt atgataatat taaggaatac aatttttaag ggggagtaat atggctagaa
     2341 aattaataaa aaatttgggt aaaagtaaaa gtgtaaagag agtgaaactt ttatttaaga
     2401 agatttttat tactgtattc atagtagcaa gtatagttgc tatttttaat ataacgaaat
     2461 attttgagga attatacaaa gtaagggatt taaaaagtac taaaattgaa tactatatgg
     2521 atgtggctga tgaagcagga gatggaaagg tccaattaag ttggaaggcc ttacttgcta
     2581 tagacatggt aatacatgat gaagatttaa gtaatataaa aaagaaagac acattggata
     2641 taggggaaaa gtttatagta gaagataaaa atgataaagg cgaaaaggtg tataaggtaa
     2701 aaaagtttaa taaggtatta agcgaattga aatttgactc ttctcaaaaa agtagagcaa
     2761 gaaaatacat gaaagattta gaatacacat accttggaaa taaacaatta gatagtagtg
     2821 atgaaaaaat taaatttata aagaagttag aagactcagc tataagagaa tatattgatt
     2881 atggaatatt gccctctata acaattggac aagctatatt agaatctggt tggggaaatt
     2941 ctaaacttac aaaacagagt aataatttat ttggtataaa agcagataaa gcatggaaag
     3001 gaaaaagtgt agaaatttca acttcagagc attataatga aaaaattgta gctagtttta
     3061 ggtcgtataa ttcattacaa gattctgtca aagaccacag tttattttta attaataata
     3121 aaagatatag aaaacatgga ttgtttgagg caaaagatta tattagtcaa gctcaatcat
     3181 tagaaaatgc aggatatagt acagcagaag ataaaaaagg aaatcgtata tatgcagagc
     3241 tattaataga tgttattagg agttataatt tgcaattgat agataataaa gttgagacaa
     3301 aataattgtt aactttatat gaggagataa caagataaga ttcttttcta caaaaagaat
     3361 agaaaaattg taaaaaaaac taaaaaaatg tattgacttg ttatttaaaa ggtgatatta
     3421 ttattactgt actcgaaaga gaacaaaa
//
LOCUS       DAMJVG010000163         3344 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.169, whole genome shotgun sequence.
ACCESSION   DAMJVG010000163 DAMJVG010000000
VERSION     DAMJVG010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3344)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3344)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3344
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.169"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            129..509
                     /locus_tag="PC512_003674"
     CDS             129..509
                     /locus_tag="PC512_003674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443365.1"
                     /translation="MKNNTSDSRVKYFCKCPYCGFDNEVEVKKGSKPKICCICTKEVE
                     YEKLEQQSVLENTEIKEVCNQMKIKKLALATGEVFENIELKEFENKGECLPPNMVKVI
                     DGKQELLINKEFILSLEVKRKTTF"
     gene            complement(499..651)
                     /locus_tag="PC512_003675"
     CDS             complement(499..651)
                     /locus_tag="PC512_003675"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443366.1"
                     /translation="MVIPIAKNTKQTSKTVASKASKILKDGRYSAASKSVAGSALSQT
                     KKGPKK"
     gene            710..907
                     /locus_tag="PC512_003676"
     CDS             710..907
                     /locus_tag="PC512_003676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2443367.1"
                     /translation="MAINDNINKILRDRDLKAWKLAKEIGVDSGNLYAILRGENKNPT
                     IDTLIKLADYLDVTLDELVGR"
     gene            946..1152
                     /locus_tag="PC512_003677"
     CDS             946..1152
                     /locus_tag="PC512_003677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015558246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443368.1"
                     /translation="MAKAVAKEQLFYRAKDIAKILDVCEATAYKIIGELNKELEKEGW
                     KTFPGRVSVTYFKERYCYKTKKGA"
     gene            1565..1882
                     /locus_tag="PC512_003678"
     CDS             1565..1882
                     /locus_tag="PC512_003678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443369.1"
                     /translation="MKSLIIVRNSVEQQLNRANLEINKNEQLYTKLRKKEERNISEEI
                     ELSNALREKSVNERLKIFAESLLKIIDTQIEIKEYEESEDYKIFELISEELERDIPID
                     VQI"
     gene            1965..2474
                     /locus_tag="PC512_003679"
     CDS             1965..2474
                     /locus_tag="PC512_003679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HDF2443370.1"
                     /translation="MSTLYELTTDLLEIEEGLTETTGNEAEKLEEIKEIIKQEIQNKN
                     TRIVSVILNIDSDINSIDSEIKRLQELKRAKKNTLDKLKSNIKDCMELLETKKVETIL
                     GNISIRKSAGSLVIEDEEKIPAIYKTVEQVVKVDKNTIKDFIKKGHEVEGCRIEYGTT
                     LTIPKAKKE"
     gene            2484..3092
                     /locus_tag="PC512_003680"
     CDS             2484..3092
                     /locus_tag="PC512_003680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ERF family protein"
                     /protein_id="HDF2443371.1"
                     /translation="METNNVYIKLVNIQSTLKAPKSQFNSFGKYNYRSCEDILEGLKP
                     ILKEEKALVVLDDNIVQIGNRFYVEATATLIDAETGEKISVKALAREDETKKGMDLAQ
                     VTGSVSSYARKYALNGLFCIDDTKDSDATNKHGNEQKKKEVNESELNILYSLGESIEK
                     DKNRVDSEVYKKFGKLAVDLTKQEYEKVLNGYKSILEKQKQE"
     gene            3102..>3344
                     /locus_tag="PC512_003681"
     CDS             3102..>3344
                     /locus_tag="PC512_003681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HDF2443372.1"
                     /translation="MGIIRVSKDKDNPYVVLNKTCLEDVKLSWQAKGLHSYLISKPDH
                     WKIYVNDLYKRSKNGRDATANILKELIENGYVTRKPC"
BASE COUNT         1479 a          314 c          625 g          926 t
ORIGIN      
        1 attaataagt ttaaaaagaa caatcaaata tcaatgttag gttaaagatt aatagcactt
       61 tgaaaactaa atacagaata ttttgaaata tattgtttta attaattatt aactaggagg
      121 ttaaatacat gaaaaataat acaagcgatt caagagtaaa atatttttgc aagtgtccat
      181 attgtgggtt tgataatgag gtagaagtta aaaaagggtc gaagcctaaa atatgttgta
      241 tatgtacaaa agaagttgag tatgaaaaat tggagcaaca aagtgttttg gaaaataccg
      301 aaattaaaga agtatgtaat caaatgaaaa ttaaaaaatt agcactagca acaggagaag
      361 tatttgaaaa tatagagctc aaagaatttg aaaataaagg agaatgctta ccaccaaata
      421 tggtaaaggt tattgatggt aagcaagaac ttctaataaa taaagagttc atattatcat
      481 tagaagtcaa aagaaagact actttttagg acctttctta gtttgtgaca aagcactacc
      541 agcaaccgat ttggaagcag cactatatct tccgtcttta agaatcttac tagccttaga
      601 agcaacagtt ttacttgttt gtttagtatt tttagctata ggtatcacca cctttaaatg
      661 tatttatagg atttatccta caaatatagt atatcaaagg agggaaataa tggcaattaa
      721 tgacaacata aataaaattt taagagatag agatttaaaa gcgtggaaat tagcaaaaga
      781 aataggcgta gattcaggaa atttatatgc aattttaaga ggagaaaata aaaatccaac
      841 tatagataca ttgataaaac tagctgacta tttagatgtt acattagacg aattagttgg
      901 aagatagaaa ttaaatacag aatattttga aagtaggtgt attgtatggc aaaagcagta
      961 gctaaagaac aattgtttta tagggcaaaa gatatagcta agattttaga tgtatgtgaa
     1021 gcaaccgctt ataaaataat tggagaatta aataaagaat tagaaaaaga aggttggaag
     1081 acctttcctg gaagggtatc agtaacttat ttcaaagaaa gatattgtta taaaacaaaa
     1141 aaaggggcat aaaaaatgct atgagagtag ctaaagatat gtttcctaaa gtaattgtat
     1201 aaagaggaag ggggtgattt agttgaatgt aagagtactg atagcttata tacagttttg
     1261 taagcaatac aataagaaag cgagttttga aggtcttaaa aaatacaata aggggatagt
     1321 gatataaaaa aacttaaagt aaaatttcct acaaaaattc ttaaagcagg taaagcaatc
     1381 agagtaacat gtgcaagatt tggttttgaa agcgattgta taataactca atcgcaagaa
     1441 tttgaattaa cagtagttta ttttgataaa gaattagatg atttagtaca atcgtctata
     1501 actatagatg atgcaataag ctatgattat tgcattgaaa cgttaaatta agaggggatt
     1561 aatcatgaaa agtttaatta tagtgagaaa ttcagtagag caacaactaa atagagctaa
     1621 tttagaaata aataaaaacg agcaacttta tacaaaactt agaaaaaaag aagaaagaaa
     1681 tatatcagaa gaaattgaat tgagtaatgc tttaagagaa aaaagtgtaa acgaaagatt
     1741 aaaaatattt gctgagtcat tactaaaaat tatagataca caaattgaaa taaaagaata
     1801 tgaagaaagc gaggattaca agatatttga attaatttca gaagaacttg aaagagatat
     1861 acctatagat gttcagatat aagaaaagag ccactgcaat ggctctaatc aaaaatatat
     1921 caaaaattta attagctata ttatagcata aatggaggga aattatgagt actttatacg
     1981 aattaactac agatttatta gaaatagaag aaggtttaac agaaacaaca ggaaatgaag
     2041 ctgaaaaact agaggaaata aaagaaataa taaaacaaga gatacaaaat aaaaacacta
     2101 ggatagtttc agtaatatta aacattgaca gtgatataaa ctctatagat tcagagatta
     2161 aaagattgca agagttaaaa agggccaaaa agaatactct tgataaatta aaaagcaata
     2221 taaaagactg tatggaatta cttgagacta aaaaagtaga aacaatttta ggaaatataa
     2281 gtataagaaa gtcggcaggt agcttagtca tagaagatga agaaaagata cctgctatat
     2341 ataaaacagt tgagcaagtt gtaaaagtag ataagaacac tattaaagac tttattaaaa
     2401 aaggtcatga ggttgaaggt tgtaggattg aatatggaac tacactaaca attccaaaag
     2461 ctaaaaaaga gtaggtgagg accatggaaa ctaataatgt ttatataaaa cttgtaaata
     2521 tacagagtac tttaaaagct cctaaaagtc aatttaatag ctttggtaaa tacaactata
     2581 ggagttgtga ggatatacta gaaggtttaa agcctattct aaaagaagaa aaagcattgg
     2641 ttgtattgga tgataatatt gttcagatag gaaatagatt ttatgtagaa gctacagcaa
     2701 ctttaataga tgcagaaaca ggagaaaaaa tatctgtaaa agcattagct agagaagatg
     2761 aaactaaaaa aggtatggat ttagcacaag taactggaag tgtatcaagt tatgcaagaa
     2821 agtatgcttt aaatggatta ttttgtattg atgatacaaa agatagtgat gcaacaaata
     2881 aacatggaaa tgagcagaaa aaaaaagaag ttaatgagag cgaattaaat atactatatt
     2941 cgctaggaga atctatagaa aaagataaaa atagagttga tagtgaagta tataagaagt
     3001 ttggaaagtt agcagtagat ttgactaagc aggagtatga gaaagtttta aatggatata
     3061 agagcatttt agagaagcaa aaacaagagt aggtgatagt attggggatt ataagagtaa
     3121 gcaaagacaa agataatcca tatgtagttt taaataaaac ttgtttggaa gatgtaaaat
     3181 taagctggca agcaaaaggc ttacattcat atctgattag taagcccgac cattggaaaa
     3241 tctatgttaa tgacctatat aaaagaagta aaaatggaag ggatgctaca gcaaatattt
     3301 taaaagaact tatagaaaat ggatatgtaa caagaaaacc ttgt
//
LOCUS       DAMJVG010000164         3312 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.170, whole genome shotgun sequence.
ACCESSION   DAMJVG010000164 DAMJVG010000000
VERSION     DAMJVG010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3312
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.170"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(22..387)
                     /locus_tag="PC512_003682"
                     /pseudo
     CDS             complement(22..387)
                     /locus_tag="PC512_003682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423610.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
     gene            complement(408..1487)
                     /locus_tag="PC512_003683"
     CDS             complement(408..1487)
                     /locus_tag="PC512_003683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF917 domain-containing protein"
                     /protein_id="HDF2443373.1"
                     /translation="MRFLTEESVDKIAVGAAVLGTGGGGDPYVGKLVAKQAIKKYGPV
                     KVISLDELDDDALVVPVSGMGSPVITIEKLLSEVELTTPLEIMEKLLNRKVDVIIPIE
                     IGGINSLMPIAVAAKKGLPILDADSMGRAFPEAQMVTFYLEGYEASPAVMSDEKGNSA
                     ILYPVDGIWSERLARTLTVEMGGSSSISDYNLSGAQVKKAAIGNTLTIAETIGGFLLE
                     NKSDSKGAVENILKELRGYKLFEGKVIDIKRELKGGFTRGHAFFAGINEYDGEYSILF
                     QNENLIAKKGDTPLCITPDLIAVLDLETGFPITTERIKYGSRVMVVAFPCNEKWRTEK
                     GIETVGPGYFGYDVEYKTVEELQGK"
     gene            complement(1541..2830)
                     /locus_tag="PC512_003684"
     CDS             complement(1541..2830)
                     /locus_tag="PC512_003684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HDF2443374.1"
                     /translation="MEEEKINYALEQIPENQKRGWVAMFSVLVAIGVDLSSVILGAEL
                     AQSMPMKQAILSVIVGSFFSAILYTTCSLVGSSTSLSTSMITKYVFGEAGAKIFSLVI
                     GVSLLGWFGVQVGFFAQNAQIIIKDIFNLDVSMQILSLIGGLLMMSTAIYGYKAMEKL
                     SVYSVPFLLVLMMLTIFLAFRANGISVDDNMKSTMTFAGGVSLSMSIIIVGAIVSPDI
                     SRWAKSRRDCALSSFLGIQFGNAFMIIVSIVLVKCMGTSDIMRIFITLGIAIPGIIVL
                     TLAQWTTNTSNVYSASLSIALVLKKAPEKVLTIVLGIIATLLAVFGIYEGFIGFLNLL
                     GIVIAPVGGVYTAEYYIVKQELKGFDKGVLYKPIVKRSIVSWIIGILITYLSTYGFIT
                     LTTIAPLDGFIAGFVVQSIIGKVLCSTKNKQEIDKAV"
     misc_binding    complement(2993..3204)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
BASE COUNT         1093 a          662 c          364 g         1193 t
ORIGIN      
        1 agtgtgcgta gctatttttt aatcaaactc atatccacca gataccaata ttgaatctaa
       61 ttctattttt tctcttaagt cttctggcca atctataaat ggaagaatgg cagtagtggc
      121 tggctttcct attcttatca tagccacatt attaagtctt tttctttcta caatagcatt
      181 tgtacaatga gttgtaccaa gcatagcata ttttattaat gaatggtcaa tcttactttc
      241 atctataact ttttttaagg cattgtaaac accagtttca acatcttttg tagttgccac
      301 cttaactgaa tgaattactt ttaattcccc atccagtata caagcatctg tatttgttcc
      361 tccaacgtca attcctacac gatacatcaa aatttcctcc taaactttta ttttccttgt
      421 aattcttcta ctgttttata ttccacatca tatccaaagt atccaggtcc aactgtctca
      481 attccttttt ctgttctcca tttttcatta caaggaaaag ctactaccat aacacgagag
      541 ccatatttta ttctctctgt agttattgga aatccagttt ctaaatctaa tactgctatt
      601 aaatctggtg taatacaaag tggtgtatca ccttttttgg caattaaatt ctcattttgg
      661 aataatatag aatactctcc atcatactca ttaatcccag caaaaaaggc atgtcctcta
      721 gtaaatccac ctttcaactc tctcttaata tcaattactt ttccttcaaa taacttgtat
      781 ccacgcaatt cttttagtat attctcaaca gcaccttttg aatcagattt attttcaagt
      841 aaaaaccctc ctatagtttc agctattgta agagtattac ctatagcagc ttttttaact
      901 tgagctccac ttaaattata gtcactaata gaagaacttc ctcccatttc tacagttaaa
      961 gttctagcta atctttctga ccaaattcca tccacaggat aaaggatggc agaattacct
     1021 ttttcatcag acattacggc aggagatgcc tcatatcctt caagataaaa agttaccatt
     1081 tgagcttcag ggaaagctct acccatagaa tctgcatcta agataggaag tcctttttta
     1141 gcagcaactg ctataggcat aagtgagttt atccctccta tttctatagg aattataaca
     1201 tccacttttc tatttaataa tttctccatt atttctaaag gggtagttaa ctcaacttct
     1261 gaaagtaatt tttctattgt aattacagga gaacccatac cagatactgg aactaccaaa
     1321 gcatcatcat caagttcatc taaacttatt acttttacag gaccatactt tttaatggct
     1381 tgttttgcaa ccaatttacc tacatatggg tcacctccac ctccagttcc aagcactgct
     1441 gcaccaactg ctattttatc tacactttct tctgttaaaa atctcatgtt actttctcct
     1501 catatttcta atttatttta tactttataa acaaatttct ttatactgct ttgtctattt
     1561 cttgcttatt ttttgttgaa caaagcactt ttccaataat agattgtact acaaaccctg
     1621 ctataaaacc atctaaaggt gctatagtag taagagttat aaatccatat gttgaaaggt
     1681 aagttattaa tataccaatt atccaagaca ctattgaacg tttaactatt ggtttatata
     1741 atactccttt atcaaagcct ttaagttctt gctttactat gtaatattct gctgtatata
     1801 caccaccaac aggtgcaatt acaattccaa gtaaatttaa aaatcctata aaaccttcat
     1861 atattccaaa tacagccaat aatgttgcta taataccaag gactatagtt aatactttct
     1921 caggagcctt cttaagtaca agagctatac ttaatgatgc tgaatataca ttacttgtat
     1981 ttgtagtcca ttgtgctaat gtaagtacta ttatacctgg tatagcaatt cctaatgtaa
     2041 taaaaattct cataatatct gaagttccca tacattttac taatactatc gaaactatta
     2101 tcataaaagc atttccaaat tgtattccca aaaagcttga aagagcacag tctcttctac
     2161 ttttagccca acgacttata tcaggagata caattgcacc aactattatt atactcattg
     2221 acagagaaac tccacctgca aatgtcatag tagatttcat attatcatca actgaaattc
     2281 catttgctct aaaagctaag aatatagtta gcatcataag aactaataaa aatggtactg
     2341 aatacacact caacttctcc attgccttat atccataaat tgcagtactc atcatcaaga
     2401 gaccacctat taggcttaaa atctgcatac ttacatctaa attaaatata tcttttatta
     2461 ttatctgtgc attttgagca aagaaaccta cttgaactcc aaaccaacct aatagagaaa
     2521 cccctataac tagagaaaat atttttgctc cagcttctcc aaatacatac tttgttatca
     2581 tagatgtaga taaacttgta gatgagccaa ccaaagagca tgtagtatac aaaattgcag
     2641 aaaaaaatga accaacaatt actgacaata ttgcttgttt cattggcata ctctgtgcca
     2701 actcagcgcc taaaataaca gatgataaat ccacacctat tgctactaaa actgaaaaca
     2761 tagctaccca accacgtttt tgattctctg gaatctgttc cagagcatag ttaatttttt
     2821 cttcttccat tttcatccct ccatttaaat cgtaaaacta ctgaccttag catattttac
     2881 aattttctaa tttataaatt tattaactat catattttta taattttcat ttaatatata
     2941 gttttaaatt ttctgaaata agtttataat aaaaaacgcc tcttggaaaa atccaagaga
     3001 cgaatataaa tccgtgttac cactcttatt agtaaaaatt aattttactc actcattttc
     3061 ttaaggcgaa ttaaaccact attctaacat aattacaata gtattctcca aagtcctttt
     3121 cacataaatt ccaatattag ttctcagcca aatctaactc tctgtaaaat tcctttatgc
     3181 tactttcttc ttctacgaat atataatatt gatttgtagt taatttatga tttatatcat
     3241 aatatatatg caatattttg tcaacttaaa aagtcaatta cttgcatttt ttagttttat
     3301 atgtaaattt tc
//
LOCUS       DAMJVG010000165         3264 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.171, whole genome shotgun sequence.
ACCESSION   DAMJVG010000165 DAMJVG010000000
VERSION     DAMJVG010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3264)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3264)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3264
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.171"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            2..613
                     /locus_tag="PC512_003685"
     CDS             2..613
                     /locus_tag="PC512_003685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HDF2443375.1"
                     /translation="MINDIKNKFKNYKPYINGYKNMKRASVLIPIVEINNTHYILFEV
                     RSKNLKHQPSEISFPGGKIESGETPYEAVIRETCEELGTFSDNIEVISSLDLLITPVK
                     FIIHPYLGYIKNINNLNINKDEVDHTFLVPIKYLLENPPNTYSNTVKVFPDENLPYGS
                     IPNQKDYKFESGSYPILFYKYKDYVIWGMTAKILENFLNFLSE"
     gene            911..1249
                     /locus_tag="PC512_003686"
     CDS             911..1249
                     /locus_tag="PC512_003686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3784 domain-containing protein"
                     /protein_id="HDF2443376.1"
                     /translation="MFAVGFVVIIALAFFILSVLLFNGKASMLLAGYNSMSKKEKARY
                     DKKKLCRSSSIVTFIVSIMLFIMAFLGYRIESGQMDEKKMVPFSIIFIIVILSSVFFN
                     ILYSNKKCKK"
     gene            complement(1656..3092)
                     /gene="miaB"
                     /locus_tag="PC512_003687"
     CDS             complement(1656..3092)
                     /gene="miaB"
                     /locus_tag="PC512_003687"
                     /EC_number="2.8.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (N6-isopentenyl
                     adenosine(37)-C2)-methylthiotransferase MiaB"
                     /protein_id="HDF2443377.1"
                     /translation="MSKRKQVTIPIEKIQEQDKYIEQIHRQNEEYFNRTGKRKLVFTQ
                     TFGCQMNEHDSEKLCSMLEEMGYQMSMMVEESDLIIYNTCAVRENAELKVYGNLGQLK
                     HLKGKNPDMKIAVCGCMMQQPHVVEELRKKYKHVDLIFGTHNLYKFPQLLTESINSDK
                     MLVDVWDVDGEVIEGLRSNRKFELKAFVNIMYGCNNFCTYCIVPYTRGRERSRTPEDI
                     INEIKELVANGTKEITLLGQNVDSYGKTLENPVSFSELLRKVNDIEGIERVRFMTSHP
                     KDISDEVIYAIRDCDKVCEFLHLPIQCGSSSLLKKMNRHYTKEYYLEIIEKAKKEVPG
                     IAFSTDLMIGFPGETEEDLLDTLDVVEKVRYDSAFTFIYSKRQGTPAAKMENQIPEDI
                     KHDRFNRVLEAVNRISAEINDGYKDRIVEVLVEGRSKNNENKFAGRTRQNKLVNFEGG
                     NDDLIGKLVMVKITEPRTFSLNGILVNN"
BASE COUNT         1129 a          478 c          369 g         1288 t
ORIGIN      
        1 aatgataaac gatattaaaa ataaattcaa aaattacaaa ccatatataa atggatacaa
       61 gaatatgaag agagcatctg ttttaattcc aatagtagaa ataaataaca cacactatat
      121 attatttgaa gttcgctcaa aaaatttgaa gcatcaacct agtgaaattt cttttccagg
      181 tggtaaaata gaatcaggtg agactccata tgaagctgtt attagagaaa cttgtgagga
      241 acttggaact tttagtgaca atatagaagt aatatcaagt cttgacctcc ttataacacc
      301 agtaaagttt atcatacatc catacttagg atatataaaa aatattaata atttaaatat
      361 aaacaaggat gaagttgacc atactttttt ggttcctata aaatatcttt tagagaatcc
      421 tccaaatact tatagtaata ctgtaaaagt ttttccagac gaaaatctac catatggttc
      481 aattccaaac caaaaagatt ataaatttga aagtggaagt tatcctattc tgttttataa
      541 atataaagat tatgtaattt ggggaatgac agcaaaaata ctagaaaact ttttaaattt
      601 tttatcagaa taacactcat aataaatcat caaaactttt acataagaaa tttataaaag
      661 tttctaaatt taacaattct aaaatatcaa taactatatt ttgtagcact tttttatttt
      721 attattgttt gaatatttga tggttttcaa tgcaatttca acataaatac tatgtattag
      781 tgtatactgt tgatgaatta aagtatgata atctatttaa taaagtatga agtaaatgat
      841 tttaatgtgc ctttatggta aaattactaa taagtaataa aattaattaa aatatatgga
      901 ggtgcttata atgtttgctg taggatttgt tgttataatt gcacttgcct ttttcatttt
      961 aagtgtacta ttatttaatg gaaaagccag tatgctacta gcaggttata actctatgag
     1021 taagaaagaa aaagcacgat acgataaaaa aaaattatgt agaagttcta gcattgttac
     1081 ttttattgtc tctataatgc tatttattat ggcgtttttg ggatatagaa tagagagtgg
     1141 tcaaatggac gaaaaaaaaa tggttccctt ttctataata tttataatag tcatactttc
     1201 cagtgtattt tttaatatcc tctactctaa caaaaaatgt aaaaaataaa tagttgtaag
     1261 ttgagcagtt aattataaaa gattgactgc tttttcatgt atattgacta ctcttattaa
     1321 atattttaac atttaaaaat ctatgtaaaa ataatgaata tagtacaaac ttctaataat
     1381 gattttacct ttgtggttac agtccactat atataattta atatgataac agggaattac
     1441 taatgacaac taggtaagct tttataaaat ataataaaac aaaaatagat gtacaatgaa
     1501 attatatctt atatcaaatt tatttttatt aatagcaaaa acttacatta gcataacata
     1561 tgacaaattc gcttaaaata aaaattttta atataatttg ttctatagta catctatttt
     1621 gattagttta cataatttta ttattttgta caatattaat tatttactaa tatcccattt
     1681 aatgaaaaag ttctaggttc agtaattttt accataacta atttaccaat taaatcatca
     1741 tttccacctt cgaaatttac gagtttattt tgtctagttc taccagcaaa cttattttca
     1801 ttatttttac ttcttccttc aactagaact tcaactattc tatctttata tccatcattt
     1861 atttctgcag aaatcctatt tacagcttct aacaccctat taaatctatc atgctttata
     1921 tcttctggta tttgattttc cattttagca gcaggagttc cctgtctttt agaataaata
     1981 aatgtaaaag ctgaatcata tctaactttt tcaaccacat ctaaagtgtc caataaatct
     2041 tcttctgttt ctcctgggaa accaatcatt aagtctgtag aaaaagcaat acctggaact
     2101 tcctttttag ctttttctat tatttctaaa taatattcct ttgtataatg tctattcatt
     2161 tttttcaaaa ggctactgct tccacattgt attggtagat gtaaaaactc acacacctta
     2221 tcacaatctc taattgcgta tattacttca tcagatatat cttttggatg agatgtcata
     2281 aatcgaaccc tttcaattcc ttctatatca ttcacttttc ttaaaagttc tgagaatgaa
     2341 actggatttt caagtgtctt accataagaa tctacatttt gtccaagtaa agtgatttct
     2401 ttcgttccat ttgcaacaag ctcttttatc tcgttaatta tatcttcagg agttctactt
     2461 ctttctcttc ctcttgtgta tgggactata caatatgtgc agaaattatt gcatccatac
     2521 attatattta caaatgcttt taattcaaat tttctattac ttctaagacc ttctattact
     2581 tctccatcca catcccatac atccactaac attttgtcag aatttattga ttctgtaagt
     2641 aattgcggaa atttatatag attatgtgtt ccaaatataa ggtctacatg tttatatttt
     2701 tttcttaatt cctctacaac atgtggttgt tgcatcatac atccacatac agctattttc
     2761 atatctggat tttttccttt tagatgtttt aattgtccta agttaccata cacttttagc
     2821 tctgcatttt ctctaactgc acaggtgtta tatattatta aatcactttc ttcaaccatc
     2881 attgacattt ggtatcccat ctcttctaac attgaacata atttttctga atcatgttca
     2941 ttcatttgac acccgaaggt ttgagtaaac acgagttttc tctttccagt tctgttgaag
     3001 tattcttcat tttgtctgtg tatttgttct atatatttat cttgttcttg tattttctct
     3061 ataggtattg ttacttgttt tcttttgctc acgtctattc ctcctagtta atttcttata
     3121 ttacacataa ccttaattat atcaaataag aaaaatcttt taaagatatt attatttttc
     3181 tagttgtgtt ttaatagtaa atctaatgat ttatatatac tatatttcta aaatataaaa
     3241 tcatataatt attataataa taaa
//
LOCUS       DAMJVG010000166         3161 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.172, whole genome shotgun sequence.
ACCESSION   DAMJVG010000166 DAMJVG010000000
VERSION     DAMJVG010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3161)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3161)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3161
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.172"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            102..2459
                     /locus_tag="PC512_003688"
     CDS             102..2459
                     /locus_tag="PC512_003688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HDF2443378.1"
                     /translation="MDKVNLERYSCDINVGLNKNQLQSRIDDNLINAFDNGKTKTYKQ
                     IFKDNIFTLFNLINIVLVCLLVSVGSFKNTLFIFIAVINTIIGVIQEIRAKRLLDNLS
                     VIVSNKVSVIREKEKKEIDVQELVLDDIMILKTGNQICADSKVLNGKLEVNESLVTGE
                     SDIIIKNKGDFLYSGSFVVSGEAFVRVENIGKDNYANKIANDAKISKKHNSQLRNSLN
                     AILKIVGIIIIPLGIILFAKQHFGNGDSIATSVVGTVAAVNGMIPEGLTLLTSIALAV
                     GTIKLASHKTLVQELYCVETLARVDTLCLDKTGTITEGKMQVDDIVMLEEVDINEIMG
                     NICNSLKDDNATLNAIRDKYNVLDTYKAKNLIPFSSERKYSGVTFENKGTYLLGAFEF
                     IFKEKNKKLRIEVERYSKKGNRVIVLAHSDSYMEDNNIPEDIKPLAFILILDKIRDEA
                     KETLEFFYNEGVDIKIISGDNPITVSEVARKAGLKTASNFIDATTLKNDSDIYKAVDK
                     YSVFGRVSPQQKKQMILALKKQNHTVAMTGDGVNDVLALKEADCSIAMASGSDVTKNV
                     SNLVLLDSNFASMPKVVMEGRKVINNIQRASSLFLVKTIFSFFLSLLTLFFFSRQYPF
                     VPIQLSLIGAVTVGIPSFFLALEANKSRISGNFLLNILKNALPGALCVTVNVIIVYNI
                     VEYLGYSSSVFSTMCAILTGVCGLLILRQQCLPFNKERLFLIVSMTIAFVIGILFLGG
                     LFSFVALSRELILITMALAILMPIMIKVMLFVLDEILETIVPDLN"
     gene            complement(2545..2862)
                     /locus_tag="PC512_003689"
     CDS             complement(2545..2862)
                     /locus_tag="PC512_003689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine/purine nucleoside phosphorylase"
                     /protein_id="HDF2443379.1"
                     /translation="MSEFKNVTAVKKANVYFDGKVSSRVIILPNGERKTLGLMLPGEY
                     TFSTREEEIMEMLAGSMDVKLPGSNEFVTYKEGQKFNVPSDSSFDLKVNEVVDYCCSY
                     IAD"
BASE COUNT         1229 a          337 c          506 g         1089 t
ORIGIN      
        1 tattatataa actatagaat aataaaataa aaaaattgag aattttataa tatatttgta
       61 gatttgagta taaaaaagtg ctaagttgaa aggagtaaaa tatggataag gttaatttag
      121 aaaggtatag ttgtgatata aatgttggtt taaataaaaa tcaacttcaa agtagaatag
      181 atgataattt aattaatgca tttgataatg gaaaaaccaa aacatataaa caaattttta
      241 aagacaatat atttacactt tttaatctca taaatattgt tttagtctgt ttattagttt
      301 cagttggttc ttttaaaaat accttattta tatttattgc tgtaattaat actattatag
      361 gagtaataca agagataaga gctaaaagat tattggacaa tctatctgtt atagtttcaa
      421 ataaggtatc tgtcataaga gaaaaagaga aaaaagagat tgatgtacaa gaattagtat
      481 tagatgatat tatgatttta aaaacaggta atcaaatttg tgcagattca aaagttttaa
      541 atggaaaatt agaggtaaat gagtctttgg ttacaggtga atctgatatt attataaaaa
      601 ataaaggcga ttttttatat tctggaagtt ttgtagtttc tggagaagct tttgtaagag
      661 ttgaaaatat aggaaaagat aactatgcaa ataagatagc taatgatgca aagatttcta
      721 aaaaacataa ttctcaactt agaaattcat taaatgcaat attaaaaatt gtaggtataa
      781 taataattcc tttaggaatt atattgtttg caaaacaaca ttttggaaat ggagattcta
      841 tagctacatc tgtagtaggt acagtggcag ctgtaaatgg tatgatacca gagggattaa
      901 cattacttac gagcattgct ctagctgtag gaactataaa acttgctagt cataaaactt
      961 tagtgcaaga actgtactgt gtagagactc ttgctagagt tgatacacta tgtcttgata
     1021 agacaggtac aattacagaa ggtaaaatgc aagttgatga tatagtaatg ttggaagaag
     1081 tggatattaa tgaaataatg gggaatatat gtaattctct caaagatgat aatgcaacac
     1141 taaatgcaat aagagataag tataatgttt tagatacgta taaagctaag aatttaatac
     1201 cattttcttc agaaagaaaa tacagtgggg ttacctttga aaataaaggt acatatttat
     1261 taggtgcatt tgagtttata tttaaggaaa aaaataaaaa acttaggata gaagttgaaa
     1321 gatattctaa aaaaggaaac agagtaatag ttttagctca tagtgattct tatatggaag
     1381 ataataatat tcctgaagat ataaagccac tagcttttat attgatattg gataaaatta
     1441 gagatgaagc taaggaaact ttagaatttt tttacaatga aggtgtagat ataaaaatta
     1501 tatctggtga caatcctata acagtaagtg aggtagctag aaaagcaggt cttaaaacag
     1561 ctagtaattt tattgatgca acaacactta aaaatgatag tgatatatac aaagcagttg
     1621 ataaatacag tgtttttgga agggtaagcc cacaacagaa aaaacaaatg attttagcat
     1681 taaaaaaaca aaatcataca gtagctatga ctggagatgg tgtaaatgat gtactagcac
     1741 ttaaagaagc ggattgtagc attgccatgg catctggaag tgatgttact aagaatgtgt
     1801 ctaatttagt cttattagat tcaaactttg catcaatgcc aaaggttgtt atggagggaa
     1861 gaaaagtaat taataacatt caaagagcat cttctttgtt tttagtaaag acaatttttt
     1921 cattcttctt gtcgttatta acattattct tcttcagtag acagtatcca tttgttccta
     1981 tacaattatc actcattggg gctgtaacag tgggtatacc atcattcttc ttagctcttg
     2041 aagcaaacaa aagtagaatt tcaggaaatt ttttactcaa tatattaaaa aatgctttac
     2101 caggagcact atgtgtgaca gtaaatgtaa ttattgttta caatatagtt gaatatttag
     2161 gttatagttc aagtgtattt tccacaatgt gtgctatatt aactggtgta tgtggtcttt
     2221 taatattgag acaacaatgt ttgccattta ataaagaaag attattttta atagtaagta
     2281 tgactattgc atttgttatt gggattctat ttttaggtgg attattctca tttgtagcat
     2341 tgagtagaga attaattctc ataactatgg cattagcaat attaatgcca attatgataa
     2401 aagttatgtt atttgtctta gatgagatat tagagacaat tgttccagat ttaaattaat
     2461 tttaaaatga tataaataag agcagtttta gttgaactgc tctttttaga tgtgtttaat
     2521 tttatgtaag aatatgtatt tttattaatc agctatatat gagcaacagt agtcaacaac
     2581 ttcattaacc tttaagtcaa aacttgaatc actaggaaca ttaaattttt gcccttcttt
     2641 ataagttaca aactcattgc ttccaggcag ttttacatcc atacttccag caagcatctc
     2701 cattatttct tcttctctag tagaaaaagt gtattctcct ggcaacatta atcctaaagt
     2761 ttttctttct ccattaggca gtattattac tctgctactt accttaccat caaaataaac
     2821 gtttgccttc tttactgcag taacattctt aaattcactc attagataaa acctccaaaa
     2881 ttatttgtac atatatatta tataaaaata atgtaaaaaa tgctatatat ttacaaaaaa
     2941 atttagtatt tattaaaaaa attaataaga ataaaaaaga ggtgaaattg cttaaattga
     3001 taaaaaatat aaaataaatt gcaaagtaag caagaaaaga ataagttgaa gagttatata
     3061 ttataaatat taaaaatttt agtattaata aaaaagatat tacattaata tgaaaatata
     3121 ggagattaga agtgtttgat taaaaaatag ctacacacac t
//
LOCUS       DAMJVG010000167         3045 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.173, whole genome shotgun sequence.
ACCESSION   DAMJVG010000167 DAMJVG010000000
VERSION     DAMJVG010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3045)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3045)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3045
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.173"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            94..849
                     /locus_tag="PC512_003690"
     CDS             94..849
                     /locus_tag="PC512_003690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003399531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2443380.1"
                     /translation="MLQIKNLSKSFPNPYGEPNTIFENLSIDIEDGEFVSIIGSNGTG
                     KSTLLNIISGLIKESSGQITLDSTTITNLAEYKRTQIVSRVFQDPSLGTCPSMTVREN
                     LSLALNKGKLLNLKKCLRHKTNDLEHLLEGISLDLKKYLDIKVQYLSGGQRQSLSLIM
                     SSLASPKVLLLDEHTAALDPKTSNEVIELTDKIVREKNITTLMVTHNLKHALQYGDRL
                     IMLHKGEVVLDVKDKEKKDLTVEEILEKFEYAV"
     gene            946..1983
                     /locus_tag="PC512_003691"
     CDS             946..1983
                     /locus_tag="PC512_003691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2443381.1"
                     /translation="MIKSKKILSLIIAGVLGVSMLTGCSQNDGSNASNENKETDSKKQ
                     KNIGITQLVEHPSLDKAKKGFIKALEDKGYKDGDNIKIDFQNAQNDMPTTQSIASKFV
                     SDKKDLIYAISTPSAQAAYNATKDIPIIMTAVTDPVEAGLVKSLEKPGGNVSGTSDYL
                     SIDKTLELVKTLTPKAKKIGVIYNTSEVNSKIQVDSLHDYAKKNNYEVVEKGISSSSE
                     VNQAISSLVGKIDVLYVPTDNLIVSSMPIVSKVANENKIPIIASEEGSVSSGALACCG
                     IDYEKLGYKAGELAIEVLEGKSVGDIPVTTLDETEIIINEDTLKALDMQKLSADNIKY
                     IKSDENAKSTK"
     gene            2792..>3045
                     /locus_tag="PC512_003692"
     CDS             2792..>3045
                     /locus_tag="PC512_003692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2443382.1"
                     /translation="MSGIISVMTQSLILSIMALGVYITYKILDFPDMSADGSYTMGAS
                     IVAFSLTNGISPVVATLMAILCGCTAGLVTGILHIKFKIS"
BASE COUNT         1168 a          393 c          461 g         1023 t
ORIGIN      
        1 ctttcctagc tactggtaac ttaaatattt cactaaaaaa aaacaaatgc aaagctagta
       61 ccaaaaataa atcagaaaaa agaggtgttg tagatgttac aaattaaaaa tctttcaaag
      121 agtttcccta atccatatgg tgaacctaat actatctttg aaaatttatc aatcgatata
      181 gaagatggtg aatttgtaag tatcataggt agtaatggaa ctggtaaatc tactttatta
      241 aatataatat ctgggcttat aaaagaatct tctggtcaaa ttactttaga tagtactact
      301 ataacaaatt tagctgagta taaaagaact caaatagtaa gtagagtttt tcaagaccca
      361 agccttggaa cttgtccttc tatgacggtt agagaaaatt tatctctagc acttaataaa
      421 gggaaattat tgaacttaaa aaaatgtctt cgtcataaaa cgaatgactt ggaacactta
      481 cttgaaggaa tttctttgga tttaaaaaaa tatttagata ttaaagtaca atatctttca
      541 gggggtcaaa gacaatcact atcactaatt atgtctagct tagcaagtcc taaggtctta
      601 ttactagacg aacatacagc agcacttgac ccaaaaacat caaatgaagt aatagagtta
      661 acagataaaa tcgtaagaga gaaaaatata actacactta tggttactca caacttgaaa
      721 cacgctcttc aatatggaga taggttgata atgcttcata agggtgaagt tgtattagat
      781 gtaaaagata aagaaaaaaa agatttaaca gttgaagaaa tcttagaaaa atttgaatat
      841 gcagtataag aaattaaaat cttagtttta atcagaaata tttataatct atcatatgaa
      901 tatatgaaca aatataatta ttaaatttta agggaggaaa ataaaatgat aaaaagtaaa
      961 aaaatattaa gtttaattat agcaggagta cttggtgtat caatgcttac tggatgttct
     1021 caaaatgatg gctccaatgc ttcaaatgaa aataaagaaa cagatagcaa aaaacaaaaa
     1081 aatataggta ttactcaatt agtggaacat ccatctctgg ataaagcaaa gaaaggattc
     1141 atcaaagcac ttgaagataa aggctataaa gatggagata atataaaaat agatttccaa
     1201 aatgcacaaa atgatatgcc tactacacaa agtattgcta gtaagtttgt atccgacaaa
     1261 aaagatttga tatatgctat atctactcca tctgcacaag cagcttataa tgctactaaa
     1321 gatattccaa taataatgac tgctgttaca gaccctgtag aagctggact tgttaaatct
     1381 cttgaaaaac caggtggaaa tgtttctggt acatctgatt atctttcaat tgataaaaca
     1441 ttagaattgg ttaaaacatt gactccaaaa gcaaagaaaa taggggttat atacaatact
     1501 agtgaagtta attcaaaaat ccaagttgat tctctacatg attatgctaa gaaaaataat
     1561 tatgaagtag ttgaaaaagg aatcagctct tcaagtgaag ttaaccaagc tatttctagt
     1621 ttagttggta aaatagatgt tttatatgtc cctactgaca atttaatagt ttcttctatg
     1681 ccaatagttt ctaaagttgc taatgaaaac aagattccta taatagcctc tgaagaaggt
     1741 tctgtatctt ctggtgcttt agcttgttgt ggaatagatt atgaaaaact aggttataag
     1801 gctggagaac ttgctattga agtattagaa ggaaaatctg ttggcgatat accagttact
     1861 acattagatg aaactgaaat aataattaac gaagatacac taaaagcact tgacatgcaa
     1921 aagttatcag cagataatat aaagtatata aagtcagatg aaaatgcaaa atctacaaaa
     1981 taaaacttat taatttcaaa aaataggtaa tatgaagtag gtaatatgaa aactttatat
     2041 aataagtact cttatccacc ctaacccttt gaaaattgtg cttattgtag caatttgaat
     2101 attgcatata aagttattca ttttccataa aagtcgtcta tattgacgac tgattatgaa
     2161 agttatataa ctttctaatc actacttgag ctgtccaaaa gaattttaat attctccaga
     2221 cagctttttt ttatgatatt tgattgatat acatgtctag ttattccata tttagtaaat
     2281 attttgataa aatttccaca ttcacttata acttaggata acgttttttt caaacaatac
     2341 attaatttaa aagtattctg agtatacatt atttagtatt ttaattaaat ttagcagttg
     2401 acttttatta ttgtataatt tataatttat aacaagtcga gaatacatat aattttctga
     2461 ctaattaaaa tattaaaagg gagagataat tatgaatact ttattaaaca atagaaaata
     2521 ttattattat tatagccact atttttaggg tttgtaccta cgttttaaca tagatacaga
     2581 ccccttaaga ctactaaaat tttgggattg tatctatgtt ggctatattg tttataaagt
     2641 tttcatttaa ctatataaga gccacataga ttaaactatg tggcttattc gtgtttttac
     2701 cacatagttt tgtacactat gtggtttttt tatacacaaa attagcaaat aattaaaatt
     2761 ataaaaatat tttcaaagga gtgttttatt tatgtcaggt attatatctg taatgacgca
     2821 aagtttaatt ttatcgatta tggcactggg ggtttatata acttacaaaa tcttagattt
     2881 tccagatatg tctgctgatg gtagctacac aatgggtgct tctattgtag cattttctct
     2941 tactaatggt atttctcctg tagtagcaac tttaatggct atcttatgtg gttgtactgc
     3001 tggtcttgtt acagggattc ttcacattaa gtttaagata tctaa
//
LOCUS       DAMJVG010000168         3015 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.174, whole genome shotgun sequence.
ACCESSION   DAMJVG010000168 DAMJVG010000000
VERSION     DAMJVG010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3015)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3015)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3015
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.174"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            155..1048
                     /locus_tag="PC512_003693"
     CDS             155..1048
                     /locus_tag="PC512_003693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HDF2443383.1"
                     /translation="MKNKKFIVIILIISILIGVLVKEYSSREIKKDDINVSKYIKYAD
                     LASKNNAQVNWKYVASIVAVLNKNNLKNVKDSQIQEVSDLFVKNFSKNNKINKLSDIL
                     DELEFSNRQKRLVDNYIDNLKDYGIKPERLKSDTKYMKFIDEIKTEAIQNYKDYKILP
                     SITIAQAIIESSWGKSTLAKQYSNLFGIKADAYWKGKSVTLETKEHLDTIIDDKFRIY
                     DDKNESIKDHAKFLATNKRYKNNGVFDAKTYIYQAKALEKAGYSTAKDENGNSIYAAR
                     LIELIQQYNLQLIDSEIQSEM"
     gene            1485..1976
                     /locus_tag="PC512_003694"
     CDS             1485..1976
                     /locus_tag="PC512_003694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443384.1"
                     /translation="MYENNKVIYNLERCEKLEKTLYLSQFNTYKNFKLASKKTVINSL
                     ETYVYNMNINNISLVDTIECISLEDEQLTGKKLILVGDIDIDAILDYAGNKRNRNSSK
                     KNTFKLKIPFSTFIQMPRKIENKDKINLKYLIQDITSSILDDNLFISVTAIISYENSS
                     KIE"
     gene            2004..2951
                     /locus_tag="PC512_003695"
     CDS             2004..2951
                     /locus_tag="PC512_003695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443385.1"
                     /translation="MRITKTTFNDVFSSDANESIIKVEKYVDKKCASVFEILTYTIIV
                     TNTNRYKTGNIFFKDYISKYIEFINNTVKVNGIIKRGLDPQQGFYIGRIDASCKKIIS
                     FKSVVLPNSAHRIIKNSANIYYYYKCNLDKFPTRISIESNRVYTNVNKIVFKQLNISN
                     TLKAPKNLRDILKVNVNSKIFDVKPMKNLINKGSNLKLCNLIVFGCIEVEIDYSCKNR
                     SNFKTVNKSNDIKKDKYYKNDIQNNNENINDCKKQISFGDNKVKKITKTFGFSCFICS
                     PVGIIYEDMKNINIKIEHTSINELNPEELFVNTSLLLYY"
BASE COUNT         1320 a          264 c          427 g         1004 t
ORIGIN      
        1 tgtgtgatag aaaactatat attataacaa tagtagtgct tttaattaaa tatatttcat
       61 aaatcttcat aaaatcttca aaatttcgta aagaatatgt cacaaaagta aggtatatta
      121 tattcagcag atagtataag ggaggacaat atttatgaag aataaaaaat tcattgttat
      181 aatactgata atatcaattt taataggtgt attagtgaag gaatattcat ctagagagat
      241 aaaaaaggat gatataaatg tcagtaagta tataaaatat gctgatttag caagtaaaaa
      301 taatgcacaa gttaactgga agtatgtagc ttccattgtt gctgtgttaa ataaaaataa
      361 cttaaaaaac gttaaggatt cacagataca agaagtatca gatttatttg ttaagaattt
      421 ttctaaaaat aataaaataa ataagttaag tgatattttg gatgagttag aatttagtaa
      481 tagacaaaaa agattggttg ataattatat agacaatctt aaggattatg gtataaaacc
      541 agaaagattg aagtctgata caaaatatat gaagtttatt gatgaaatta aaacagaagc
      601 aatacaaaat tataaggatt ataaaatact tccatctata actattgcac aagctataat
      661 agaatctagc tggggcaagt caactttggc aaaacaatat agcaatctat ttggtataaa
      721 ggctgacgct tattggaaag gtaagtcagt gactttagaa acgaaagaac atttagatac
      781 aattatagat gataaattta gaatatatga tgataaaaat gaatctataa aagaccatgc
      841 aaaattttta gccacaaata aaaggtataa aaacaatggt gtatttgatg caaaaacgta
      901 tatatatcaa gctaaagcat tagaaaaggc aggttatagt actgcgaagg atgaaaatgg
      961 caatagtata tatgcagctc gtctaataga attaattcaa cagtataatc ttcaattaat
     1021 agacagtgaa attcaaagtg aaatgtaact ttgattaaat ttttattgat aaggctatga
     1081 tttttaaaat catagcctta ttttgacatg cttttacttg taattattaa atcgatatca
     1141 ttatctttca aaatttactt tatactgtaa atcaaattat ttaagttaaa acttggaatt
     1201 atttataaaa ggattattta ctttatctaa attctgcact taaagaacat cttttccctt
     1261 aagactgacc gttagtctat aaaaattata attacttata aaaaagtgaa tatatatata
     1321 aagttttcag aaagactttt acttgtaaat tgaaatcaat gaagtaaaaa aggattcttt
     1381 cttaaaagta aataacaact agatagtgaa taataaaaaa tggtaatttg aaataatttt
     1441 tatgaatagt attaatatat agatacaggg agattgatgc gattatgtat gaaaataata
     1501 aggtaatata caaccttgaa agatgtgaaa aactagaaaa gactctttat ttatctcaat
     1561 ttaatacata taaaaatttt aaattagctt ctaaaaaaac tgtaataaat tcattagaga
     1621 catatgttta caatatgaat attaacaata taagtcttgt tgatactata gaatgtatat
     1681 cattagaaga tgaacaactt acaggaaaga agttgatttt agttggtgat atagatattg
     1741 atgcaatatt agattatgca ggaaataaaa gaaatagaaa ttctagtaaa aaaaatacat
     1801 ttaaattaaa aatacccttt agtacattta tacaaatgcc tagaaagata gaaaataaag
     1861 ataaaattaa tttaaagtat cttatacaag atattacttc atctatttta gatgataatt
     1921 tatttattag tgttactgca attataagtt atgaaaatag ttccaagata gagtaatctt
     1981 taaattatag aaaggtggat gcaatgagaa taacgaaaac tacttttaat gatgtatttt
     2041 caagtgatgc aaatgaaagt attataaaag tagaaaaata tgttgataaa aaatgtgcat
     2101 ctgtatttga gattttgacc tacactatta ttgttacaaa tacaaatagg tacaaaactg
     2161 gaaatatatt tttcaaagat tatatttcta aatatataga gtttataaat aatactgtaa
     2221 aagttaatgg cattataaaa cgtggattag acccacagca aggtttttac atagggagaa
     2281 tagatgcaag ttgtaaaaaa ataatatctt ttaagagtgt agttttacca aattctgcac
     2341 ataggattat aaagaatagt gctaatatat actattatta taagtgtaat ctagataaat
     2401 tcccaacaag aatatcaata gaaagtaata gagtttatac taatgtaaat aaaattgtat
     2461 tcaaacaatt gaatataagt aatactttaa aagctcctaa aaatctaaga gatatattaa
     2521 aagtaaatgt aaatagtaaa atatttgatg ttaaacctat gaaaaatctt ataaacaaag
     2581 gtagtaattt gaaattatgt aacttgatag tttttgggtg tatagaagtt gaaatagact
     2641 atagttgtaa aaataggagt aattttaaaa cagtaaataa gtctaatgac attaaaaaag
     2701 ataagtatta taaaaatgat atacaaaata acaatgaaaa tataaacgat tgtaaaaagc
     2761 aaataagttt tggtgataat aaggtaaaaa aaataacaaa aacttttgga ttttcttgtt
     2821 tcatttgttc tccagttgga attatttatg aagatatgaa aaatataaat ataaaaattg
     2881 aacatacatc aataaatgaa ttaaatccag aagaattatt tgtaaataca tcacttttat
     2941 tgtattatta agtattttaa agctaaaact taaacttatt aaaatagcat ttggttaaag
     3001 gaaaatagat attga
//
LOCUS       DAMJVG010000169         3007 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.175, whole genome shotgun sequence.
ACCESSION   DAMJVG010000169 DAMJVG010000000
VERSION     DAMJVG010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3007)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3007)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3007
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.175"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            296..2431
                     /gene="rnr"
                     /locus_tag="PC512_003696"
     CDS             296..2431
                     /gene="rnr"
                     /locus_tag="PC512_003696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HDF2443386.1"
                     /translation="MIPGLKESLLGLINESAYNPLKKEELAEIFDIHSSEMPMFYNFL
                     NELEEDGYICFTKKGKIVSPNQMGYFVGKFVSHKKGFGFVESDVEYTQDLFISSDNIN
                     GAMHNDRVMAEIVVPATEEKRAEGRIVKVIKREITRIVGTFQSSKTFGFVTPDNKKFT
                     KDIYIPKKHFSGAVDNDKVVCEITVWPQEDRKPEGKIIEILGQKGERGVEIDSIIREH
                     GLPEEFPKKVLQEAEAVAVEIPQEEIKRRRDLRDLNIFTIDGDDAKDLDDAISIEVLP
                     NGNFKLGVHIADVTHYVREKNKLDKEALKRATSVYLVDKVIPMLPKTLSNGVCSLNPF
                     EDKLTLSIFMEIDHKGNVVKHEICESVINSKARMTYTEVSDILEKDDEKLKKTFEHVV
                     EDFKNAEILARILMSRREKRGAIDFNFPEAKIILNGKGEVVDIKPYERRISNKIIEEF
                     MLISNETIAEHFYWMGIPFVYRIHETPSLEKMEELSKFISTFGYIIKGDKEEVHPKAL
                     QGIIEKIKGKKEEGAISTIMLRSLKQAKYSPECSGHFGLAAKFYCHFTSPIRRYPDLQ
                     IHRIIKESLNNKISGKRQEQLTTIVDYASVQSSEKERKAELAERDVHDFYKALYMKDK
                     VGQEFEGVVSSVTSFGIFVELDNTIEGLIRLANMNDDYYIYDESSYSVLGERTKKSYK
                     IGDLVKIKVESVNVDFKEIDFEIVEKIEE"
BASE COUNT         1324 a          276 c          551 g          856 t
ORIGIN      
        1 taccaatcct atttgatggt gtataattag gtgataaaga gtaatttaag caattatgat
       61 aaagaataac ttaagtaatt ataatgatat ttacaaataa tttataaaac atcataattt
      121 gtttgaagtt agtatgacaa agattacatt aaatcaaaaa tataaataag taattttaac
      181 ttataataat aagaaaatat agaaaattat gtgataagta aaaaatgttt tgtctgaaga
      241 aatataaaag acaatataaa taataatata atgaaaagta aaacaggagg gaaaaatgat
      301 accaggactt aaagaaagtt tgctaggatt aataaatgaa agtgcatata atcctctaaa
      361 aaaagaagaa ttagcagaaa tatttgatat acattcatca gaaatgccaa tgttttataa
      421 ttttttaaat gaattagaag aagatggtta tatctgcttt actaaaaaag gaaaaatagt
      481 atctcccaat caaatgggat actttgttgg aaaatttgta tcacacaaaa agggttttgg
      541 atttgtagaa tctgatgttg aatatacaca ggatttattt atctcaagtg acaatataaa
      601 tggtgctatg cataatgata gagttatggc agaaatagta gtacctgcaa ctgaagaaaa
      661 gagagcagaa ggaagaatag taaaagtaat aaagagagaa ataactagaa tagtaggtac
      721 cttccaatca agtaaaactt ttggatttgt aacaccagac aacaagaaat ttactaaaga
      781 tatatatata cctaaaaaac attttagtgg agcagtagat aatgataagg tagtatgtga
      841 aattacagta tggccacaag aggatagaaa accagaaggc aaaattatag agatactagg
      901 tcaaaaaggt gaaagaggcg tagaaataga ttctataata agagaacatg gtcttccaga
      961 agaatttcca aagaaagtat tgcaagaagc agaagctgta gctgttgaga ttcctcaaga
     1021 agagataaaa agaagaagag atttaagaga tttaaacata tttactatag atggagatga
     1081 cgcaaaagac ttagatgatg ccatatcaat agaagtatta cctaatggaa acttcaaact
     1141 aggagttcac atagctgatg ttacacatta tgtaagagag aaaaataaac ttgacaagga
     1201 agccttaaaa agagctacat cagtttattt agtagataaa gtaattccaa tgttgccaaa
     1261 aactctttca aatggagtat gtagcttaaa tccatttgaa gataagctaa ctctttctat
     1321 atttatggaa atagaccata aaggaaatgt ggttaaacat gaaatatgtg aatctgtaat
     1381 aaattcaaaa gctagaatga cttatacaga agtatctgat atattagaaa aggatgatga
     1441 aaaacttaaa aagacttttg aacatgttgt tgaagatttt aaaaatgctg aaattttagc
     1501 taggattctt atgtcaagaa gggaaaaaag aggagctata gacttcaatt tcccagaggc
     1561 aaagataatt ctaaatggaa aaggcgaagt tgtagatata aagccatatg aaagaagaat
     1621 atctaataag ataatagaag aatttatgct tataagtaat gagacaattg ccgaacattt
     1681 ttactggatg ggaataccgt ttgtgtatag aatacatgag acaccatctt tggaaaaaat
     1741 ggaagaattg agtaagttta tatctacatt tggatatata ataaaaggtg ataaagagga
     1801 agtacatcca aaagcattac aaggtataat agagaaaata aagggcaaaa aagaagaagg
     1861 agctatcagt actataatgc ttcgttcttt aaaacaagct aagtactcac cagaatgtag
     1921 tggacatttt ggattagcag ctaaattcta ctgtcacttt acttcaccaa taagaagata
     1981 tcctgacctt caaattcata gaataataaa agaatcttta aataataaaa taagtggaaa
     2041 aagacaagaa cagcttacta ctatagtgga ttatgcatct gttcaatcat ccgagaaaga
     2101 aagaaaggca gagttagctg aaagagatgt acatgatttc tataaggctc tttatatgaa
     2161 ggataaagtt ggtcaagaat ttgagggtgt tgtatctagc gtaacttcat ttggaatatt
     2221 tgttgagtta gataatacca tagaagggtt gataagactt gcaaatatga atgatgatta
     2281 ctatatttat gatgagagtt cttatagtgt tttaggagaa agaactaaga agtcatataa
     2341 gataggtgac cttgttaaga taaaggttga aagtgttaat gtagatttta aagaaattga
     2401 ctttgagata gttgaaaaaa tagaggagta gataaaacag ctaaaataag agataacaag
     2461 ttgtagtatt tatgatatgt ataaatatat agtgcacaat actctataaa ataaatgata
     2521 aaaataggta attgagaaat atctaatgga aatagttaac tgaaagataa ataattaaga
     2581 aatatttaat gaaagtagct aattgaaaaa taagtaattg agaaatgttt aatagaaaga
     2641 gctaactgaa agataagtaa ttaagaaaca tttaatagaa aaagccaact gaaaaataaa
     2701 taattaagaa atgtttaata gaagtggcta attgaaaaat aagtaattaa gaaatgctta
     2761 atagaagtgg ctaattgaaa aataagtaat taagaaatgc ttaatagaag tggctaattg
     2821 aaaaataagt aattgagaaa tgcttaatag aagtggctaa ttgaaaaata agtaattaag
     2881 aaatgcttaa tagaagtggc taattgaaaa ataaataatt aagaaatgtt taatagaagt
     2941 gactaattga aaaataagta attaagaaat gcttaataga agtggctaat tgaaaaataa
     3001 gtaattg
//
LOCUS       DAMJVG010000170         2894 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.176, whole genome shotgun sequence.
ACCESSION   DAMJVG010000170 DAMJVG010000000
VERSION     DAMJVG010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2894)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2894)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2894
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.176"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            1197..1586
                     /locus_tag="PC512_003697"
     CDS             1197..1586
                     /locus_tag="PC512_003697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2443387.1"
                     /translation="MTIKKLPQSELKIMKFIWKSDSKVTSRDIVLGMEQKYQWKQTTT
                     LTLLSRLVVKRFLNSQKIDKYTHYEVLIKEKEYIGVETRDFFRNIHDSSIKSLLLSLH
                     ENINLSKDDILLIEEWIKNLKEEEKDV"
     gene            2320..2790
                     /locus_tag="PC512_003698"
     CDS             2320..2790
                     /locus_tag="PC512_003698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase/bleomycin resistance/dioxygenase
                     family protein"
                     /protein_id="HDF2443388.1"
                     /translation="MKYQVSLLAVKDIEVSKKFYKELFEQEIELDLGKNVTFKGGFAI
                     QEDFAWLTGINPDTIIQKSNNMELYFEVDDFDEFIEKLNYYKDVEFVHKPLKHEWQQR
                     VVRIYDPDKHIIEIGESMEVIARRYLSEGYSVEETSKIIQHPIKFVKQCENSKE"
BASE COUNT         1294 a          173 c          525 g          902 t
ORIGIN      
        1 ctttgtaata tataaataaa aaaactctaa aatagaagga tataattata tagaatgttt
       61 caattaaaca aggcaaaaac tataatctta aaattaacat tattcttaag aagtaagaaa
      121 tttaagaagt aaaaagttta gttataagtg gtagtaagca agaaatttaa gaagtaaaaa
      181 gtttagttat aagtggtagt aagcaagaaa tttaggaagt gggaagttta gttataagtg
      241 gtagtaagta agaaatttag gaagtgggaa gtttagttat aagtagtagt aagtaagaaa
      301 tttaggaagt gggaagttta gttataagta gtagtaagta agaaatttag gaagtaggaa
      361 gtttagtaat aatttgtagc aagtaagaaa cttaggaagt gggaagttta gtagtaataa
      421 tttatagcaa gtaagaaatt taggaagtag gaagtttagt aataatttgt agcaagtaag
      481 aaatttagaa agtaggaagt ttagtaataa tttatagcaa gtaagaaatt tagggagtag
      541 gaagtttagt aataatttat agcaagtaag aaatttaggg agtaggaagt ttagtaataa
      601 tttgtatcaa gtaagaaatt tagggagtag gaagtttagt aataatttat agcaagtaag
      661 aaatttagaa agtaggaagt ttagtaataa tttatagcaa gtaagaaatt tagaaagtag
      721 gaagtttagt agtaatttat agtaagtaag aaatttagta agtgagaagt ttagttataa
      781 tttatagtaa gtaagaaatt tagtaagtga gaagttcagt aataagttgt agtaaataaa
      841 aagtttagga agtaggaagt tcagtaataa gttgtagtaa ataaaaaatt taggaagtag
      901 gatttactga aatacaaata tttaaaatca aagagtttaa aagaaaggag agctactgga
      961 caagtatcca aaatagatag ctgagtacaa aatatttcat aaaattaagc aatataatac
     1021 aagagaattt tgacattatt tatatatatt taccgtgtac aaatagctaa atttaggatt
     1081 aagattgaaa aatatcttat aagtctgagc ttatataaat ccgtataaga tgtatttaat
     1141 cgaaaaattt tattatggat attgcttgtc tatattctga gtagcaaggt tttatcatga
     1201 ctataaaaaa gttgccacaa tcagaattaa agataatgaa atttatatgg aaatcagatt
     1261 ccaaagtaac atctagagat attgttttag gaatggagca aaaatatcaa tggaaacaaa
     1321 cgacaacttt gactctttta tctagattag tagtaaaaag atttctaaat tctcaaaaga
     1381 tagataaata tacgcattat gaagttttaa ttaaagaaaa ggaatacata ggagttgaga
     1441 caagagattt ttttagaaat attcatgatt cttctataaa aagtttattg ttgtcattac
     1501 atgaaaatat taatttgagc aaagatgata tcttacttat tgaagagtgg ataaaaaatc
     1561 taaaagaaga ggagaaagac gtataagcaa acgtatttct tatagcatca atataaagtg
     1621 tatgtaagtg tatttatgta atatattagt ctacttaagt aatatgacaa atgattataa
     1681 gtggattatg atactataat gtgaatctaa ataaattaaa taaaaattaa tagtggatat
     1741 tctatttaat taaatttaaa aagctacctt tacttataag tataattaag gtagcttttt
     1801 aaatagaggt agtgtaatta aagagaattt ttaaatataa attgtgaagc tttaatatag
     1861 atgataatat atattttgca aatatgacac agtgttttcg tatttaagat gataaaataa
     1921 ataggaatta atgatgatat tgaaaaaata aaaataaagg attaatataa gatattaaag
     1981 agatagagat aaaagtgtta acagaagata ttgaaaaaat aaaagattga tataagatac
     2041 tgaagaggta gaaacaaaag tattaataga agatattgaa aaaataaaaa caaaagattg
     2101 atagaaagta ctgaatagat agagataaaa gtgttaatag aagatattga aaaaataaaa
     2161 gattgatata agatactgaa gaggtagaaa caaaagtgtt aatagaagat actaaaaaag
     2221 taaaaataaa ggattaataa aaggtactga agagatagag aaaaaaatgt taatagaaga
     2281 tactgaaaaa atagaaataa aaaattagga ggaaaattta tgaaatatca ggtttcatta
     2341 ttagcagtga aggatattga agtatcaaaa aaattttaca aagaattatt tgagcaagaa
     2401 attgaattgg acttaggtaa aaatgtaaca tttaaaggag gatttgctat acaagaagac
     2461 ttcgcatggc ttacagggat taatccagat acaattatac aaaaatcaaa taatatggaa
     2521 ctttattttg aggttgatga ttttgacgaa tttattgaaa aactcaatta ttataaagat
     2581 gtagagtttg tccataagcc actaaaacat gaatggcaac aaagagtagt gcgtatttat
     2641 gacccggata agcatattat tgagatagga gagtctatgg aagttatagc tagaagatat
     2701 ttatctgagg gatactctgt agaagaaact tctaaaataa ttcaacatcc aattaaattt
     2761 gtaaagcagt gtgaaaatag taaggaatga ttgtttaaat tataattatt tagtagaaat
     2821 taattgtaat agaactaatt caagataata tataggacta gtatttgaca aatgtcataa
     2881 attaaattaa aata
//
LOCUS       DAMJVG010000171         2812 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.177, whole genome shotgun sequence.
ACCESSION   DAMJVG010000171 DAMJVG010000000
VERSION     DAMJVG010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2812)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2812)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2812
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.177"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            20..796
                     /locus_tag="PC512_003699"
     CDS             20..796
                     /locus_tag="PC512_003699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HDF2443389.1"
                     /translation="MEYIIFDLEFNQGFDKKLNKTVSNEKCPFEIIQIGAIKLDSKFN
                     IIDTFNSYVKPTIYKDIHPFISRMTNIKNSDFNDSPTFPEVYNNFIKFISSQDPILCV
                     WGAGDLKELYRNINYHKLPSNSLPKSYINIQQHASKYFNNPAGKSIGLQNAISILELD
                     EKMSYHNALNDAYYTAKVFIKIYNPSIVPDIYLYTSIKPKTIRYSNKKRVDYDKLFDE
                     FRKILNRELTKDEKKIINLAYNMGKTNQFTLENVKQRKNK"
     gene            complement(888..1640)
                     /gene="xth"
                     /locus_tag="PC512_003700"
     CDS             complement(888..1640)
                     /gene="xth"
                     /locus_tag="PC512_003700"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HDF2443390.1"
                     /translation="MKFISWNVNGIRACVGKGFLDFFKEVDADIFCLQETKLQEGQIE
                     LDLPGYFQYWNYAERKGYSGTAIFTKKEPLKVMYGINIEEHDKEGRVITLEFEDFYFV
                     TVYTPNSQSELKRLEYRTRWEDDFIDYLTKLDNHKPVIVCGDMNVAHKEIDLKNPKNN
                     MKNAGFTKEEREKFSKLLDSGFIDTYRYFNPDKEGVYSWWSYRFNARKNNAGWRIDYF
                     CASKKLEDRLVSADIHTEILGSDHCPVELEIK"
     gene            complement(1801..2751)
                     /gene="galT"
                     /locus_tag="PC512_003701"
     CDS             complement(1801..2751)
                     /gene="galT"
                     /locus_tag="PC512_003701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HDF2443391.1"
                     /translation="MKELRIDPITNDVVIFATDRLKRPLDTADIPNEDEETNEYDEEC
                     PFCKGNEAHATDALFEIESEEGWLVKSVYNKFPIIDDMARDVYGVHEVMIESDKHNRS
                     FYNMSQKEFEDVFFMYRNRFRDLSKDDKVEYVSIFKNFLRKAGASLMHPHAQILSMSF
                     IPPEITNELLVSKEYYDSNKSSLYDDLIENEISLDRRVVYNGEAFLVLIPYATKYSGE
                     VRIIFKDKIEFGELNDNNIQELSTIFEKLFKKLYNINGYMPFNLCIHTHPTKIETKSY
                     FNVHMHIIPRKYNFGGFELGTNMYVSSMSPEDLTKKLKID"
BASE COUNT          985 a          476 c          291 g         1060 t
ORIGIN      
        1 aatttaggag ataaacttta tggaatacat aattttcgat ttggaattta accaaggatt
       61 tgataaaaaa ctcaataaaa ctgtatccaa tgaaaagtgt ccttttgaaa ttatacaaat
      121 aggagcaatt aaattggatt ctaaattcaa tataatagat acgtttaata gttatgtaaa
      181 acctacaatt tataaagaca tacatccctt tattagtcgt atgactaata ttaaaaattc
      241 tgattttaat gattcgccta ctttccctga ggtctacaac aattttataa aatttatatc
      301 atcacaagac cctatattat gtgtttgggg agctggagat ttaaaggaat tatacaggaa
      361 tatcaactat cacaagctac catcaaattc cttacctaaa tcttatatta atatacaaca
      421 acatgcatct aaatatttca ataatccagc aggaaaaagc attggcctac aaaatgctat
      481 ttctatatta gaacttgatg aaaaaatgtc ttatcacaat gctttaaatg atgcatatta
      541 tactgctaaa gtttttatta agatatacaa tccaagtata gtcccagata tatatcttta
      601 tacaagtata aaacctaaaa ctataagata ttctaacaaa aaaagagttg attatgataa
      661 gttatttgat gaatttagga aaattttaaa tcgtgaatta actaaagacg agaaaaaaat
      721 cattaactta gcttataata tggggaaaac aaatcaattt acattagaaa atgttaagca
      781 aagaaaaaac aaatagagtt tatttagata aaaaataggc atgtagatta aaaaactagt
      841 taactttaaa tttatatcta cagcccaatt tttatcataa ttaattttta ttttatctct
      901 aattcaactg gacaatggtc tgaacctaat atttcagtgt gtatatccgc acttactaat
      961 ctatcttcta attttttgga tgcacaaaaa taatctattc tccaccctgc attatttttt
     1021 cttgcattaa atctatatga ccaccaacta taaacacctt ctttatcagg attaaaatat
     1081 ctatatgtgt ctataaaccc actgtctaat aatttagaaa acttctctct ttcttcttta
     1141 gtaaaacctg catttttcat attattttta ggatttttta aatctatttc tttatgtgca
     1201 acgttcatat ctccacacac aattacaggc ttatgattat ctagtttggt taaataatct
     1261 ataaagtcgt cttcccatct agttctatat tctagtctct ttaattcaga ttgagaattt
     1321 ggcgtatata ctgtaacaaa gtaaaaatct tcaaactcta gagttatcac tctaccctct
     1381 ttgtcatgtt cttctatatt tattccatac attactttta aaggctcttt ttttgtaaat
     1441 atagcagtac ctgaataacc ctttctctca gcataattcc aatattgaaa atatcctggt
     1501 aaatctaact ctatttgccc ttcttgcaat ttagtttctt gtaaacaaaa tatatctgca
     1561 tctacttctt tgaaaaagtc taaaaatcct ttcccaacac aagctcttat tccattaaca
     1621 ttccatgata taaatttcat acttatactc ctcatctaaa cattgacaca ctccccatag
     1681 ctaaagatgg gggcttttca acaattttat tgtaaattct taattcactt ttattttaac
     1741 aatgctatac tataatttca tctaaaatta ctatttactt aatacctaaa aatatatgtt
     1801 ttaatcaatt tttaactttt ttgttaaatc ttcagggctc attgaagaaa catacatatt
     1861 tgttccaagt tcaaatcctc caaaattata ttttcttggg attatgtgca tatgaacatt
     1921 aaaatacgat tttgtttcaa tctttgttgg atgagtgtga atacataaat taaatggcat
     1981 atatccattg atattatata acttcttaaa caacttttca aatattgtag aaagctcctg
     2041 tatattatta tcatttaact caccaaactc tattttatct ttaaatatta ttcttacttc
     2101 tccactatac ttggttgcat atggtataag taccaaaaaa gcttctccat tataaacaac
     2161 tcttctatct aaacttattt cattttctat taaatcatca tacaaagagc ttttattgct
     2221 gtcataatac tcctttgaaa ccaacagttc attcgtaatt tcaggtggaa taaaagacat
     2281 agacaatatt tgagcatgtg gatgcatcaa agatgctcct gcctttctca agaagttttt
     2341 gaagatacta acatactcta ctttatcatc tttcgacaaa tctctaaatc tatttctata
     2401 cataaaaaaa acatcttcaa attctttttg actcatgtta taaaaactac gattatgttt
     2461 atcgctctct atcattactt catgaacacc atatacatct cttgccatat catcaattat
     2521 aggaaattta ttgtagacag attttacaag ccatccttct tcactttcta tttcaaataa
     2581 tgcatcagtt gcatgagctt catttccttt gcaaaatggg cattcttcat catattcatt
     2641 agtttcttca tcttcatttg ggatatctgc tgtatctaaa ggtcttttta acctatctgt
     2701 agcaaatata acaacatcat tggtaattgg atctattctt aattctttca taattaacac
     2761 ctcttagtta atagccttta atataattat atgatattta tcgtatctgt ta
//
LOCUS       DAMJVG010000172         2708 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.178, whole genome shotgun sequence.
ACCESSION   DAMJVG010000172 DAMJVG010000000
VERSION     DAMJVG010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2708)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2708)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2708
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.178"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(227..1039)
                     /locus_tag="PC512_003702"
     CDS             complement(227..1039)
                     /locus_tag="PC512_003702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2443392.1"
                     /translation="MFSIGMFSKINKITTKTLRYYEDIGLLKPEYVDEFTKYRYYTTE
                     QLPKLHQIITLKQMGLSLAEIKKAVENPEEVENILMNKEKEMLDVIKSEEYKIIKLRN
                     YLMNLKGEVNMNDVIIKSLPKVKVASMRKVLKGYDELFNLFPNVMAEEMMKTGCTCAV
                     PDYCFNIYHDGEYRETDMDVEMCQAINDLKEDTDILKFKELDAVENAVCILHNGPYST
                     LGKTYADAFKWIEDNKYKVVGNPRESYIDGIWNKESEEDWLTEVQIPVKRML"
     gene            complement(1115..2533)
                     /locus_tag="PC512_003703"
     CDS             complement(1115..2533)
                     /locus_tag="PC512_003703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium/proton antiporter"
                     /protein_id="HDF2443393.1"
                     /translation="MTELMIISGLVLLICITSSKVLYKFGVPILLIFILLGMLFGSDG
                     MVGIYFDNYELTKQLCSIGLIFIMFFGGFGTNWNMAKPVAIPSILMSSLGVIITAGVT
                     GMFCHMVIGTSLLEGLLIGAIAASTDAASVFAVLRSQKLNLKGSLASLLEVESGSNDP
                     IAYMLTLILLTLMNNSGVELIAPMVIKQIAFGLAIGFILAKLSVYILRHSNFEIEGFY
                     TIFITAIAILSYAFSEYLGGNGYLSVYISGIIIGNSRIPLKKSLVHFFDGISWIMQIM
                     LFFMLGLLSFPSKLPNVFGIAMAISIFMIVIARPLATFIVLAKFKFSNKEKLFISWVG
                     LRGAASVVFAIYAVTQGVAIENDIFHIIFFIALLSVGIQGSLIPTVARKLDLVDDNTP
                     VLKTFNDYDGEISSKLIEVNVDEGNKWANKSIIDSNIPDDILIVMIKRKEQVLIPKGS
                     TIIKTGDILVLSGDRIEELIQL"
BASE COUNT          949 a          485 c          276 g          998 t
ORIGIN      
        1 atacaattat ttataaagtc tttaataaaa atttataaat agagcatctt tagaaaacta
       61 ttataataaa aaaataagag gctgtctaaa aatatagata agcctttttt cataatcgta
      121 attataaaaa tatacttgat ttcatatgaa aaagagtgtc tcataaacta aaatgtttac
      181 tttgagacac cacctttttt attcttattt atactttgta gacatattat aacatgcgtt
      241 tcactggtat ctgaacttct gtcaaccagt cttcttcact ctctttattc catataccat
      301 ctatataaga ttctctagga tttccaacca ctttatattt attgtcctct atccatttaa
      361 atgcatctgc gtaagttttt cctaatgttg aatatggacc attgtgtaat atacaaactg
      421 cattttcaac tgcatctaat tctttaaatt ttaatatatc cgtatcttcc tttaaatcat
      481 ttatagcttg acacatttca acatccatat cagtctctct atattcacca tcatgatata
      541 tattaaaaca ataatcagga actgcacatg tacaccctgt tttcatcatt tcttcagcca
      601 ttacatttgg aaatagatta aaaagttcat catacccctt taacactttt ctcatagaag
      661 caactttaac ttttggtaaa gacttaataa ttacatcatt catattgact tctcctttca
      721 aattcataag gtaattacgt agtttaatta ttttatattc ttcactttta attacatcca
      781 acatttcttt ttctttattc attaaaatat tttcaacttc ttcaggattt tctacagctt
      841 tttttatctc agctaatgat aaacccattt gttttaaagt tattatctga tgtaatttag
      901 gtaattgctc tgttgtataa tacctatatt ttgtaaattc atctacatat tctggtttta
      961 acaaccctat atcttcataa taccttaatg tctttgtagt tattttattt attttagaaa
     1021 acattcctat agaaaacatc tcatcacctg cgcattagat ttgattaatt taagtttaaa
     1081 ctttcccctt aggttaaagt caatacaaaa taaattataa ttgtattaat tcttcaattc
     1141 tatctccact caataccaaa atatcccctg tttttataat ggttgaacct ttaggtatta
     1201 aaacctgttc ctttcttttt atcataacta ttaatatatc gtctggtata ttagaatcta
     1261 ttatactctt attagcccat ttattaccct catcaacatt tacttcgata agtttagagc
     1321 taatttctcc atcataatca ttaaatgttt ttaatacagg tgtattatca tcaactaaat
     1381 ccaactttct ggctacagtt ggtatcaatg aaccttgtat tcctactgaa agcaacgcta
     1441 taaaaaatat tatatggaat atgtcattct ctatggctac tccttgagta acagcataaa
     1501 ttgcaaaaac tactgaagcc gcacctctaa gacctaccca cgatatgaat aatttttctt
     1561 tatttgagaa tttaaatttt gctagaacta taaatgttgc taatggtctt gcaataacta
     1621 tcatgaatat agatatggcc attgctatac caaatacatt tggtaactta gaagggaaag
     1681 ataacaatcc taacataaag aataacatta tttgcataat ccatgaaatt ccatcaaaga
     1741 aatgaaccaa acttttttta agaggtatcc tactatttcc tataataata cctgaaatgt
     1801 aaacacttaa atatccattt cctccaagat actcgctaaa tgcataagaa agtattgcaa
     1861 tagctgttat aaatatagta taaaatcctt ctatctcgaa gtttgaatgt cttaaaatat
     1921 aaacagataa ttttgctagt ataaatccta tagctaaccc aaaagctatt tgttttatta
     1981 ccattggtgc aataagttct accccagaat tattcatcaa tgtcaaaaga attagtgtca
     2041 acatatacgc tattgggtca ttacttccac tttcaacttc taataatgat gcaagtgaac
     2101 cctttaagtt tagtttttga gaacgcaaca cagcaaacac agatgcagca tctgttgaag
     2161 ctgcaattgc cccaattaat aaaccttcaa gtaaactagt tcctattacc atgtggcaaa
     2221 acatacctgt aaccccagcc gtaattatta cacccagtga agacattaat atagaaggta
     2281 tagcaacagg tttagccata ttccagtttg ttccaaaccc tccaaaaaac attataaata
     2341 ttagtccaat agaacataat tgttttgtca gttcatagtt atcaaaatag attcctacca
     2401 tcccatcaga cccaaataac atccctagta agataaaaat caataatatt ggtactccaa
     2461 atttatacaa taccttgcta gaagttatac aaatcaatag tactaaccca cttataatca
     2521 ttaattctgt catagcatca actccatttc atataaattt tgtagattaa tttacatcta
     2581 caattttatt acttattcaa atataacatg acataaattt tataagttat ggtacataaa
     2641 gttcaacaaa aatttcacaa tacattaaaa tgtgagtgtt atacttaaat ttatatattt
     2701 gttttaat
//
LOCUS       DAMJVG010000173         2707 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.179, whole genome shotgun sequence.
ACCESSION   DAMJVG010000173 DAMJVG010000000
VERSION     DAMJVG010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2707)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2707)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2707
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.179"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            <1..411
                     /locus_tag="PC512_003704"
     CDS             <1..411
                     /locus_tag="PC512_003704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HDF2443394.1"
                     /translation="KTTYIKKYFEKYIGVITPNNFIELMSYLDDGMEADVIIRAIDEA
                     IANGVKNYKYVKTILNNWIEAGVKTNLELTEYQNEFERKKKNKQDKKQSNSKAVNTPN
                     VSKNKFHNFNETFTQYSPDELDDIIKKSQKVKFK"
     gene            472..645
                     /locus_tag="PC512_003705"
     CDS             472..645
                     /locus_tag="PC512_003705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="resolvase"
                     /protein_id="HDF2443395.1"
                     /translation="MARIYAQRSGSLNEQDRLELLRLLGKAGYTVKVAREKQNSKTTY
                     TYFVEYTEEQEEK"
     gene            661..1068
                     /locus_tag="PC512_003706"
     CDS             661..1068
                     /locus_tag="PC512_003706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDF2443396.1"
                     /translation="MNTITLVGRLVADAELKYLPNSGTPKITFSMAVDRRFKDKNGNK
                     ITDFIQCEQLGKHVENLVQYLVKAKPVYAVGELNIYNYKDENGCWKSITKVNVNALEL
                     LSSKNDNNAKQEYVPPGLDPQGFQAIDDDDIPF"
     gene            1142..1390
                     /locus_tag="PC512_003707"
                     /pseudo
     CDS             1142..1390
                     /locus_tag="PC512_003707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861747.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1388..1639
                     /locus_tag="PC512_003708"
     CDS             1388..1639
                     /locus_tag="PC512_003708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443397.1"
                     /translation="MIIIRSQDRLDLMRVNRVEIYDKQVFVIFEDDVKRIGVYESNER
                     AIEVLNRIQEAIIAGTKFDIINKDGVRCNKEKVFEMPVE"
     gene            1653..2018
                     /locus_tag="PC512_003709"
     CDS             1653..2018
                     /locus_tag="PC512_003709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443398.1"
                     /translation="MLKVEKYFNGSVADNIFEDDLTLRNYLALYCCVYGVRKNGELVF
                     PTSEKMLIEFNVDKNRKKKKKGSKVKLINAKTGEEKIFDSIDSAACFLRLQSQAVYQT
                     IKKKTKTRSGWKAEYIKEE"
     gene            2136..2585
                     /locus_tag="PC512_003710"
     CDS             2136..2585
                     /locus_tag="PC512_003710"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443399.1"
                     /translation="MSLIKYRGYDFENEKWIYSATIMWSNILECLVMLTEGCKWQKVS
                     NVGVCSGEWARNNQEICEGDILKGYDNSSDTSQYGVVKRDFNSIKLYLEWHYLKKFEG
                     EWIELINKTEIYHSRDYKVIGNEYENLEEVRTEFLERKESLENEYLS"
BASE COUNT         1117 a          237 c          583 g          770 t
ORIGIN      
        1 aaaaccacct acataaaaaa atactttgaa aaatatatag gtgtgattac tcctaataac
       61 tttatagagt taatgagtta cttagatgat ggaatggaag ctgatgtaat tataagagct
      121 attgatgaag caatagcaaa tggagttaag aattataagt atgtaaagac aatattaaat
      181 aattggatag aagcaggtgt aaaaactaat ttagaactta cagagtatca aaatgagttt
      241 gagaggaaga aaaagaataa acaggataag aagcagtcta atagtaaagc tgtgaatact
      301 cctaatgtga gtaaaaataa gtttcataac ttcaatgaaa catttactca atattcacct
      361 gacgaactag atgacataat taagaaaagc caaaaggtta aatttaaata aaattaaact
      421 tctaggaagt aaatatcaat atattgcttc ctagaaaagg ggaggtataa aatggcgaga
      481 atatatgcac aaagaagtgg ttctttaaat gaacaagata gattggagtt attaagatta
      541 cttgggaaag ctggatatac agtaaaggtt gctagagaga agcaaaatag caagacaact
      601 tatacttact ttgttgagta tacagaagaa caggaagaaa aatagaaggg ggctagttaa
      661 atgaatacaa taactttagt tggaagatta gttgcagatg cagaattgaa gtaccttcca
      721 aattcaggta ctccaaaaat aaccttttca atggcagtag atagaaggtt taaagataaa
      781 aatggaaata aaataactga ttttattcaa tgtgagcaat taggaaaaca tgtagagaat
      841 ctagtgcaat atcttgttaa agctaagcct gtttatgctg ttggagagtt aaatatatat
      901 aattacaaag atgaaaatgg ttgctggaaa tctattacta aggttaatgt aaatgcttta
      961 gaactacttt ctagtaaaaa tgataataat gctaaacaag aatatgtacc accaggatta
     1021 gacccacaag gttttcaagc aatagatgat gacgatatac ctttttaatt aagttaaata
     1081 gtctagggag tgattataca atattacttc ctaggagttg aaaaatattg gaggtctaag
     1141 agtgaaatat gagtgtgaga aagtgttctt agaatgcgat aagggaagtt ttgagataaa
     1201 tgatacaaga attgaagaag taacattcga gggtacagaa atagacaatc cgtttgagag
     1261 agtaaaatat gaagggactt ttacaataat atctggatgg gattctttat tgagagatat
     1321 attgtggctt gaaatgcgga aagtcttaaa aattataaca agaaaaatga tgatgggggt
     1381 attaggaatg ataataatta gaagtcaaga tagattagat ttaatgagag ttaacagagt
     1441 tgaaatatac gataaacaag tatttgtaat atttgaagat gatgtcaaac gaataggtgt
     1501 atatgaaagt aatgaaagag ctattgaagt attaaacaga atacaggagg ctattattgc
     1561 aggaactaag tttgacatta taaataaaga cggggttaga tgcaacaaag aaaaagtgtt
     1621 tgaaatgcca gttgaataag gagggagctg aaatgttaaa ggttgaaaaa tattttaatg
     1681 gttctgttgc agataacata tttgaagatg atttgactct tagaaactac ttagcactat
     1741 attgttgtgt ttatggagta agaaaaaatg gagagcttgt atttccaact tctgaaaaaa
     1801 tgctaataga gtttaatgtt gataaaaata gaaaaaagaa aaagaaaggt tcaaaggtaa
     1861 agttgattaa tgccaaaact ggtgaagaaa aaatatttga ttctatagat agtgcagcgt
     1921 gttttttaag actacagagt caggcagttt accaaacaat taaaaagaaa actaaaacaa
     1981 gaagtggctg gaaagctgaa tatattaagg aggaataatg gaagtttcaa ggactgaata
     2041 cacaattaaa agagcaaaag agttgtatga caatggagag gacatattta ttgctataga
     2101 taaggctaga gaagaatatg aggagatgat taaaagtgag tttaattaag tacagaggtt
     2161 atgattttga gaacgaaaag tggatttatt cagcaacaat aatgtggagt aatatacttg
     2221 aatgtttagt tatgttgaca gagggttgca aatggcagaa agtctctaat gttggggtat
     2281 gctctggaga atgggctaga aacaatcaag aaatttgtga aggggatata ttgaaaggat
     2341 atgataattc tagtgataca agccaatatg gagttgtaaa aagagatttt aatagtatta
     2401 agttatattt ggaatggcat tatttaaaga agtttgaagg agaatggata gagcttataa
     2461 ataaaacaga aatatatcat agtagagatt acaaagtaat tggtaatgaa tatgagaatt
     2521 tagaggaagt cagaacagag ttcttagaac gtaaggagag tcttgaaaat gaatatctta
     2581 gctagtgcga tattagtaat aggaagtttt ataactggta gagtttatga gtatagattg
     2641 aatctaaaag agtgtgaaaa ttgcgacaat aaaagaggtg tataagaatg gatgatagat
     2701 tagaaat
//
LOCUS       DAMJVG010000174         2560 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.180, whole genome shotgun sequence.
ACCESSION   DAMJVG010000174 DAMJVG010000000
VERSION     DAMJVG010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2560)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2560)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2560
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.180"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            636..2432
                     /locus_tag="PC512_003711"
     CDS             636..2432
                     /locus_tag="PC512_003711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002594337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HDF2443400.1"
                     /translation="MKPTMEILTKLQENSKKNHDEVFTRLYRYLLRPDIYYVAYQHLY
                     SNKGAGTKGVTDDTADGFSEIYIENIIEALKNEMYQPKPVRRTYIKKSNGKMRPLGLP
                     VFTDKLIQEAIRMILEAIYEPIFSDYSHGFRPARSCHTALAQIKKEFTGARWFIEGDI
                     KGCFDNINHAVLVEIINQKIKDARFLKLIRSFLKAGYMEDWKYHKTYSGCPQGGIISP
                     ILANIYLNELDRHVMKIKKEFDVATKARYTPEYTKLVGLRQRLHNKIKNSNGIEREKL
                     IEEYKSATAQMLKLPAKQCDDKKIKYVRYADDFLIAVNGNRQDCEKIKQELTEFISTT
                     LKMELSQEKTLITHSNTPARFLGYDVRVRRDQQIKPKGKFKTRSMNNKVELSIPFKDK
                     IEKFLFSNGIVKQRSDNGKLEPIHRPQLLNRTDLEIVTIYNAELRGICNYYGLASNFN
                     KLIYFNYLMEYSCLKTLAGKHRSKVSKIRAMYKDGTGKWAIPYETKTVIKKMYFANYA
                     DCKGKKFTDIVPQTAKNYSHDVTTLESRLKAKICEVCGCTESDRYEIHHVNKVKNLKG
                     KSEWEKIMIAKRRKTIVVCHKCHMAIHHGEKK"
BASE COUNT          977 a          439 c          533 g          611 t
ORIGIN      
        1 ttagaagtag attaaagaaa gggggacaga aaaaaaaggc actaccccgt aagataacac
       61 gggaaaccac ctgcctaacc gaaaggtgaa aactgtacgg gaaaatagca cggcaggaaa
      121 gcagaaagtt gttcaaagac aatagagcac gactgaactg caaggttaag tgaatatgag
      181 gataaaacta gatttgttga atgtgagttc caaacctctg ttacgtgtgg acacaggaaa
      241 cttgtctgaa acctgtggta tgagtaacgc tgaaaataaa tgcctttcag tgggttatca
      301 attaactcat acggtacgct ggagaaccag tagtaacgga acgaaagcat atccgacaat
      361 tcacaccagc ctactacttt cgtcaactgg agattaccta aaccagaatg cctacaatgg
      421 ctatgtgtaa tgctcttgta gtgataaatc acaaggctat gctaagtgag atgacgctga
      481 aaatctggca aggtaacgga gctttcatag tagtctgaga accctgaaaa gacagggaaa
      541 gccgtaaaat cggatacggg aaaaccgttc acatggcgaa ggaaagcagt cttagcgaat
      601 taaaattaga aattgattag ggaggaaaac ctcaaatgaa accaacaatg gagattttaa
      661 ccaaattaca ggaaaattca aaaaagaacc atgatgaagt atttacaagg ctctatcgat
      721 atttactccg tccagatata tactatgttg catatcaaca cctctactcc aacaaaggag
      781 caggaacaaa gggtgtaaca gacgacacag cggacggttt tagcgaaata tatattgaaa
      841 atatcattga agccttaaaa aatgaaatgt atcaaccaaa accagtaaga cgtacataca
      901 tcaaaaaatc aaatggcaaa atgcgtccct taggactgcc tgtctttact gataagctga
      961 tacaggaagc aatacgcatg atattagaag caatctatga gcctattttt tcagactact
     1021 ctcacggttt ccgaccagca agaagttgtc atactgctct tgctcaaata aaaaaagaat
     1081 ttacaggagc acgctggttt atagagggcg acataaaagg gtgctttgat aacatcaatc
     1141 atgcggtact tgtggaaatt atcaatcaga aaattaaaga tgcacgtttt ctgaaactca
     1201 ttcgttcatt cttaaaggca ggttatatgg aagattggaa ataccacaaa acatatagcg
     1261 gttgccctca aggtggcatc atttcgccta ttcttgcgaa tatctacctt aatgaattag
     1321 accgtcacgt aatgaagata aagaaagagt ttgatgtggc aacaaaggca cgttatacac
     1381 cagaatatac aaaactggta ggactacgcc aaagattaca caacaaaatt aaaaatagca
     1441 acggtataga aagagaaaag ctgattgaag aatataaatc tgcaacggct caaatgctta
     1501 aactaccagc gaagcaatgt gacgacaaga aaataaaata tgtgcgttac gctgatgatt
     1561 tcctaatagc tgtgaatggc aatcgacagg attgtgagaa gattaagcaa gaacttacag
     1621 aatttataag taccacatta aaaatggaac ttagtcaaga aaaaactctg attacacaca
     1681 gtaatactcc tgctcgtttt ctcggatatg atgtcagagt acgccgtgac cagcagatta
     1741 aaccaaaagg aaaattcaaa acccgttcta tgaataacaa ggtggaattg agtattccat
     1801 tcaaagacaa gatagagaaa tttttatttt caaatggaat tgtaaagcag aggtcagaca
     1861 atgggaaatt agaacctata caccgaccac aactgcttaa taggacagat ttggaaatag
     1921 tgactattta taatgcagaa ttaagaggta tctgtaatta ttatgggttg gcaagcaatt
     1981 ttaacaagct aatctatttc aattatctta tggaatatag ctgtttgaaa acacttgcag
     2041 gaaagcaccg ttccaaagtt tctaaaatta gagctatgta taaagacggt acaggcaaat
     2101 gggctattcc ttatgaaact aaaacagtaa taaagaaaat gtattttgcg aattatgctg
     2161 actgcaaagg aaagaagttt actgatattg ttccacaaac agctaaaaat tattcccatg
     2221 acgtaacaac attagaaagc cgattaaagg cgaagatatg tgaagtatgt gggtgtacgg
     2281 aaagtgacag atacgaaatt catcatgtaa acaaggttaa aaaccttaaa ggaaaatcag
     2341 aatgggaaaa gataatgata gccaaaagac ggaaaacaat cgtggtatgc cacaagtgtc
     2401 acatggctat acatcatggc gaaaagaaat aacctgtaac ggagcaaaga tggagagccg
     2461 tgtgcattga gaaatgcaag cacggttcgg ggagaggact gcacaaacct accctagaaa
     2521 taaggaaagg cggtgctttc ctactctact atgtgggaaa
//
LOCUS       DAMJVG010000175         2500 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.181, whole genome shotgun sequence.
ACCESSION   DAMJVG010000175 DAMJVG010000000
VERSION     DAMJVG010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2500)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2500)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2500
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.181"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            86..820
                     /locus_tag="PC512_003712"
     CDS             86..820
                     /locus_tag="PC512_003712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDF2443401.1"
                     /translation="MKQNKYDDDRFFNKYSKMERSTNGLAGAGEWHVLKKMLPDFKGK
                     RVLDLGCGFGWHCQYAVENGAISAVGVDISEKMLKEARNKTQLDNINYICMPIEDINF
                     PKDSFDVVISSLAFHYIQSFEDICKNISNCLSNKGNFVFSVEHPIFTAYGSQEWYCDK
                     DGNNLHWPVDRYFEEGVRRSNFLGEEVIKYHKTLTTYLNALMKTGFEILEIIEPQPEE
                     KLLDTIPDMKDELRRPMMLLVSAKKR"
     gene            complement(963..1454)
                     /locus_tag="PC512_003713"
     CDS             complement(963..1454)
                     /locus_tag="PC512_003713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HDF2443402.1"
                     /translation="MNNQQQEVYKKLDELSIPYEAVNHPPVYTIEEMEELKTLHMEFV
                     VKNLFLRDAKGKEHFLVVLGKDKKADLKDIRQQIDSKPLSFASEERLQKYLKLTKGAV
                     TPFGILNDKEAVVKVVFDKDLLKMDKIGIHPNDNTATVFLKFEDMKKLIEENGNEIYY
                     VEV"
     gene            1803..2186
                     /locus_tag="PC512_003714"
     CDS             1803..2186
                     /locus_tag="PC512_003714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443403.1"
                     /translation="MSTDKVVGIIDEETAELAGIEYTGKIYASSGVIKHIKKKHRCQL
                     SKDIFNDIIDTIKMVLKSPEYIGSHPKKPGKSVEFIKKIDDYILVATELDTKKGYLYV
                     SSMYAIKEAKLESRVNSGRVKQYDG"
BASE COUNT          974 a          276 c          368 g          882 t
ORIGIN      
        1 tattttatat aaaagtgata aaaacttata ttttgtattt aatagagtgt tgctaagtga
       61 atatatttaa aatggaggaa actttatgaa acaaaataaa tatgatgatg atagattttt
      121 taataaatac agtaaaatgg aacgttctac aaatggatta gcaggtgctg gagagtggca
      181 tgttttaaaa aaaatgttac ctgatttcaa aggaaaaaga gttttagatt taggatgtgg
      241 atttggatgg cattgtcaat atgcagttga gaatggagca atttctgctg ttggagttga
      301 tatttcagaa aaaatgttaa aagaagctag aaacaaaacg caacttgata atataaatta
      361 catatgtatg cctattgaag atattaattt tccaaaagat agttttgatg tagttattag
      421 ttccttggca tttcattata ttcaatcatt tgaagatata tgtaagaata taagtaattg
      481 tctttcaaat aaaggtaatt ttgtattttc tgttgaacat cctatattta ctgcatatgg
      541 aagtcaagag tggtactgtg ataaagatgg aaataatcta cactggccag tagatagata
      601 ttttgaagaa ggagtacgta ggtcaaattt tctaggagaa gaggttataa aatatcataa
      661 aacattaaca acttatttaa atgcgttaat gaaaacagga tttgaaatat tagaaattat
      721 tgaacctcaa ccagaagaaa aactgttaga tacaattcct gatatgaaag atgagctacg
      781 tagacctatg atgttacttg tatctgcaaa aaaaagataa gtaaatataa ataatcatta
      841 ttgtagaaaa aaagttgtag aaaataatta cactaatgga gatgattata ccagtggtat
      901 taattacacc agtagtaagg aggcaaaagc attcgttgct tttgccattt tttaagttgc
      961 aattatactt ctacgtagta tatttcgttt ccattttctt ctataagctt tttcatatct
     1021 tcaaatttta aaaatacagt agcagtatta tcatttggat gtatacctat tttatccatt
     1081 tttaataaat ccttatcaaa tacaactttt acaacagcct ctttatcatt taatatacca
     1141 aaaggagtca cagctccttt agtaagtttc aagtattttt gaagtctttc ttctgatgca
     1201 aaactaagag gtttactatc aatttgttga cgaatatctt ttaaatctgc ttttttgtct
     1261 ttacctaata caactaaaaa atgttctttt cctttagcat cacgaagaaa taggtttttt
     1321 acaacaaatt ccatatgtaa tgtttttaat tcttccattt cttcaattgt ataaactggt
     1381 ggatgattta cagcctcata aggtatgctt aactcatcta attttttata tacttcctgt
     1441 tgttgattgt tcatgatttc ctcccattag aaatttattt tatatataaa taatattatc
     1501 acagaaaact ttaaaagaaa acgttttata taatatagac aatagattat atttttataa
     1561 agaagcaaga atactcaata aaacttaaag aaattaaacg atttctaaaa ataccttgaa
     1621 aatagaacct tatttgccat ttataaatta tataaaaagg gattatataa agtcatatat
     1681 gaaaaaacta tattatacta tcttttcttt ttggaataaa ctatacttta aatatagata
     1741 tttaatttaa ataaatttta cagtattaat agtaaattat cttagaaagg aatgtgcttt
     1801 atatgtctac agacaaagtt gttggaatca tagatgaaga aacggcagaa cttgcaggaa
     1861 ttgaatatac tggtaaaatt tatgcttctt ctggtgttat aaaacatata aagaaaaaac
     1921 atagatgtca actgagtaag gatattttta atgatataat agacactata aaaatggtat
     1981 taaagtcacc tgaatatata ggaagtcatc ctaaaaaacc tggaaaaagt gtggagttta
     2041 taaaaaaaat tgatgattat attttagtag ctacagaatt agatacaaaa aaaggatatt
     2101 tatatgtatc ttcaatgtat gctataaaag aagcaaaatt agaaagtaga gtaaacagtg
     2161 gaagagtaaa acaatatgat ggttaacata atattattaa ttttccctaa aatattgaaa
     2221 aatattatta tataagttat aatattaata tacacgtaga tatttattag ttagatttga
     2281 ggttggaaaa ggcacccaat acgctactat agagtagtta atagagatgc aggatacgcc
     2341 gccctgccaa atctaattaa attaaaaaga gaggattaat tcctctctta ttgttttttt
     2401 gagatactaa tttaatctat aatagaaaga ttgaaggtcg tttatacaaa aaaattttca
     2461 gttatataca ttaaactaat taaataagat atttataatc
//
LOCUS       DAMJVG010000176         2443 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.182, whole genome shotgun sequence.
ACCESSION   DAMJVG010000176 DAMJVG010000000
VERSION     DAMJVG010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2443)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2443)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2443
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.182"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(207..2300)
                     /locus_tag="PC512_003715"
     CDS             complement(207..2300)
                     /locus_tag="PC512_003715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF2443404.1"
                     /translation="MNKHNFEVILNQLQINIYVTNIHTNEIIFMNKKMKEEYNILDPE
                     GKVCWQVLYPEKNSTCSFCKVLELLKNDKKGVLIKWYEKCNKLNRVFENYDSLITWQD
                     GTVVHMHQSIDIANSTSLNKPIKINEFHEISNNKEEKGVFNFSRDNFDYNSTLLYDAL
                     IRGTDEYIYICNMKTGVFRYSPSQVELFDLPGEIVENPLVYWKKIVHPEDWNRFYKSN
                     TEIGKNQMDYHTVEFRAKNRSGEYIWLRCRGQLMRDEFGEPSIFAGIMTQLGKQNKID
                     SLTQLLNYHEFMSVFEDKISNPMIEKLCIVLLDIDDFKNVNEMYDRDFGDNIIKTLAQ
                     SIQSILPDNAELYKLDGDEMGILVDNVEENEILTLYNQIQNMIIHLQLWRKYGLNITI
                     SAGCVIYPKHGDTVKELYKCASYSLQYAKEHGKNRLVFFSQEILKNKMYSLEMMRDLK
                     ASINDDFRGFSLRFQPQVDTESHKIIGVEVLLRWTNDKCKAISPLEFIPILEENDMIN
                     IVGAWVLRMALRTFRKWIDYYPFFKVSVNVSAVQILEDTFIEDIVKIIDDENFPYQNL
                     VLELTESHTVQNMSILQFKFKALQDLGIYIAMDDFGTGYSSLEVLKFSPIDIVKIDRV
                     FVKDILKSKFDATFIHFIVAICHDVGIKVCLEGVETQEEYDLVKQIKPDYIQGYLFGK
                     PQTATEIFDLLKLDN"
BASE COUNT          822 a          402 c          237 g          982 t
ORIGIN      
        1 atattatttt taatctaaaa atagatatct atttttatta tggttatccc tttttaaaat
       61 actttaatca tatactattc ccaatttaac atccattgaa atgctatttt cttatattgc
      121 aatttataat tgatatatct tcaatataat aatttaatgt atttttgatt ttaaagcttt
      181 tcagtgatat tattgataaa ttagaattaa ttatctagct ttaaaaggtc aaagatttct
      241 gttgctgtct gcggttttcc aaataaatat ccttgtatgt aatctggctt tatttgttta
      301 actaaatcat actcttcttg tgtttctaca ccttctaaac atacttttat tcctacatca
      361 tgacaaattg caacaataaa atgtataaat gtagcatcaa acttactctt taatatatct
      421 ttaacaaata ctctatcaat tttcactata tctattggag aaaattttaa aacttctaga
      481 gacgagtatc cagtaccaaa atcatccata gcaatataaa ttcctaaatc ttgtaaagcc
      541 ttaaatttaa actgtaaaat actcatattt tgtactgtat gactttctgt caattctaaa
      601 acaagatttt gataaggaaa attttcatca tctataattt ttactatatc ttcaataaat
      661 gtgtcttcta atatttgaac agctgaaacg tttacactca ctttaaaaaa aggatagtaa
      721 tcaatccatt tcctaaaagt acgtaatgcc attcgaagca cccaagcccc tacaatattt
      781 atcatatcat tttcttctaa tattggaata aattccaaag gagaaattgc tttgcatttg
      841 tcattagtcc accttaaaag aacttctaca cctattattt tatgactttc tgtatctact
      901 tgtggctgga atcgaagact aaacccccta aaatcatcat taattgatgc ctttaaatcc
      961 cgcatcattt ctaatgaata cattttattt tttaatattt cttgggagaa aaaaacaagc
     1021 ctgtttttac catgctcttt cgcatattgt aaagagtaac tagcacactt ataaagttct
     1081 tttactgtat ctccatgttt tggatatatt acacaaccag cagaaattgt tatatttaat
     1141 ccatattttc tccatagttg aaggtgtata atcatattct gtatttgatt atatagagtt
     1201 agaatttcat tttcttcaac attatcaaca agaatgccca tttcgtcccc atcaagttta
     1261 taaagttcag cattatctgg taaaatagat tgtatagact gtgctagtgt ttttattata
     1321 ttatctccaa aatccctatc atacatctca ttaacatttt taaaatcgtc aatatctaat
     1381 aatactatgc ataatttttc aatcatagga tttgaaattt tatcttcaaa tacactcata
     1441 aattcatgat aattcagtaa ctgtgtcaat gaatcaatct tattttgttt acctaattgc
     1501 gtcattattc ctgcaaaaat acttggttct ccaaattcat cacgcattag ttgacctcta
     1561 catcttaacc atatatattc tccactacga tttttagccc taaattccac tgtatgataa
     1621 tccatctggt ttttacctat ttcagtgttt gacttataaa aacgattcca gtcttctgga
     1681 tgtacaattt ttttccagta aacaagcgga ttttcaacaa tttctcctgg taagtcaaat
     1741 aattcaactt gtgatggtga atatcgaaat acgcctgttt tcatattgca aatgtatata
     1801 tattcatctg tacctctaat caaagcatca taaagcaatg tagaattata atcaaaattg
     1861 tctcttgaaa aattaaaaac tcctttttct tctttattat ttgatatttc atgaaattca
     1921 ttaatcttaa ttggtttatt taagcttgtt gagtttgcaa tatctattga ttgatgcata
     1981 tgaacaactg tgccatcttg ccatgtaatt aaactatcat aattttcaaa aacacgattt
     2041 aacttattac atttttcata ccactttatt aatactcctt ttttatcatt ctttaataat
     2101 tctaaaactt tacaaaaact acaagtagaa tttttttcag gatataatac ttgccaacaa
     2161 acttttcctt ctggatctaa aatattatat tcttctttca tttttttgtt cataaaaata
     2221 atttcattag tatgaatatt tgtaacatat atattaatct gtagttgatt taatataact
     2281 tcaaaattat gtttgttcat atacttatct cctccatagt tactgctctt tataacaaca
     2341 ttgttaaaat tattcttttt agaagattta cttataactt atacatatac actaaatacc
     2401 ttaatttaat tagaaagttt attacttcat attttaaatt ata
//
LOCUS       DAMJVG010000177         2414 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.183, whole genome shotgun sequence.
ACCESSION   DAMJVG010000177 DAMJVG010000000
VERSION     DAMJVG010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2414)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2414)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2414
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.183"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            <1..411
                     /locus_tag="PC512_003716"
     CDS             <1..411
                     /locus_tag="PC512_003716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HDF2443405.1"
                     /translation="KTTYIKKYYESYIGVITPNNFLQLLSYLDDGMEADVIIRAVDEA
                     VGSGVKNYKYIKTILNNWIEAGVKTNLELTEYQNEFERKKKSKQEKKQSNNKTVNTHN
                     VSKNKFANFNQTFTQYDEKELDEIIKKSQKEKFK"
     gene            472..645
                     /locus_tag="PC512_003717"
     CDS             472..645
                     /locus_tag="PC512_003717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="resolvase"
                     /protein_id="HDF2443406.1"
                     /translation="MARIYAQRSGSLNEQDRLELLRLLGKAGYTVKIGREKQNSKTTY
                     TYFVEYTEEQEEK"
     gene            661..1077
                     /gene="ssb"
                     /locus_tag="PC512_003718"
     CDS             661..1077
                     /gene="ssb"
                     /locus_tag="PC512_003718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDF2443407.1"
                     /translation="MNTITLVGRLVADAELKYLPNSGTPKILFRVAVDRKYKDREGKK
                     KVDFIPCEQLGKHVENLVQYLTKGKQIYAFGELNIDNYKDENGCWKSITKVNVNALEL
                     LSSKEDSNNHEKQQEYIPPGLDPQGFQAIDDDDIPF"
     gene            1148..1561
                     /locus_tag="PC512_003719"
     CDS             1148..1561
                     /locus_tag="PC512_003719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443408.1"
                     /translation="MELKFREWNKNGKEMYSYDEMVCYSKNLLREWVYSGVYLPKNNE
                     NFEVMIYTGLKDCDGKEIYEGDIVLCRSIFFTEFAGEVKFKDGCFIAVNEMSGDCFRL
                     SELAIVKVDGNIYEDLSKLNDIRRCDEGGIRNDNN"
     gene            1548..1799
                     /locus_tag="PC512_003720"
     CDS             1548..1799
                     /locus_tag="PC512_003720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443409.1"
                     /translation="MIIIRSQDRLDLMRVNRVEIGFNQVYAILENDVRKIGEYESNER
                     AMQVLNEIQKFIENGVRTDYIDSCRVRHNQEKVFEMPFE"
     gene            1817..2170
                     /locus_tag="PC512_003721"
     CDS             1817..2170
                     /locus_tag="PC512_003721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443410.1"
                     /translation="MAKVWMDAGELLEKTIDIEDMFGCNLSKMRNKSKQKGLVGRTNS
                     KGQGRKSKKVECTNIITGESKIFVSAVEASKYLYFTELHIARLARTGKTTKNGWKVRY
                     IQEVTDGIGKCGASN"
     gene            2139..2279
                     /locus_tag="PC512_003722"
     CDS             2139..2279
                     /locus_tag="PC512_003722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443411.1"
                     /translation="MVLANVEQVIKLAEKILNKKKCSVNKAIDTAIKILSRYEYEGML
                     EK"
BASE COUNT          997 a          192 c          526 g          699 t
ORIGIN      
        1 aaaaccacct acataaaaaa atattatgaa tcttatatag gtgtgattac tccaaataat
       61 tttcttcaac tactaagtta tttagatgat ggaatggaag ctgatgtaat aataagagct
      121 gttgatgaag ctgtaggcag tggagttaag aattataaat acattaaaac aatattaaat
      181 aattggatag aagcaggtgt aaaaactaat ttagaactta cagagtatca aaatgagttt
      241 gagaggaaga aaaagagtaa acaggagaag aaacagtcta ataataaaac tgtgaatact
      301 cataatgtaa gtaaaaataa gtttgctaac ttcaatcaga cttttactca gtatgatgaa
      361 aaagagctag acgagattat taaaaagagt cagaaggaaa aatttaaata aaaattaaac
      421 ttctaggaag taaatatcaa tatattgttt cctagaaagg ggaggtataa aatggcgaga
      481 atatatgcac aaagaagtgg ttctttaaat gagcaggata gattggaatt gttaagatta
      541 cttgggaaag ctggatatac agtaaagatt ggtagagaga agcaaaatag caagacaact
      601 tatacttact ttgttgagta tacagaagag caggaagaaa aatagaaggg ggctagttaa
      661 atgaatacaa taactttagt tggaagatta gttgcagatg ctgagctgaa atatcttcca
      721 aattcgggta cacctaaaat tttatttagg gtagcagtag atagaaaata caaagataga
      781 gaaggcaaaa agaaagttga ttttatacct tgtgaacagt taggaaaaca tgtagaaaat
      841 cttgtacagt atcttacaaa aggtaaacag atatatgctt ttggagaatt aaatatagat
      901 aattacaaag atgaaaatgg ttgttggaaa tctattacta aggttaatgt aaatgcttta
      961 gaattgcttt caagtaaaga ggatagtaat aatcatgaaa aacaacagga atatatacca
     1021 ccaggactgg acccacaagg ttttcaagca atagatgatg acgatatacc tttttaatca
     1081 agttaagtag tctagggagt aattatacaa tattacttcc tagaagttaa aaaatggagg
     1141 gatgaagatg gagttaaaat ttagagaatg gaataaaaat ggtaaagaaa tgtatagtta
     1201 tgatgaaatg gtgtgctatt ctaaaaattt gcttagagag tgggtttata gtggtgttta
     1261 tttgccaaaa aacaatgaaa attttgaggt tatgatatac acaggtttaa aggattgtga
     1321 tggaaaagaa atctatgaag gcgatattgt tttatgtaga agtatatttt ttacagagtt
     1381 tgcaggggag gtaaaattta aagatggttg ttttattgca gtgaatgaaa tgtcaggaga
     1441 ttgctttaga ttatctgaac ttgcaatagt taaggttgat gggaatatat atgaagattt
     1501 aagtaagtta aatgatataa gaagatgtga tgaggggggc attaggaatg ataataatta
     1561 gaagtcaaga tagattagat ttaatgagag ttaacagagt tgaaataggt tttaatcaag
     1621 tgtatgcaat acttgaaaat gatgttagaa aaataggtga atatgaaagt aatgaaagag
     1681 ctatgcaagt gttaaatgaa atacagaagt ttattgaaaa tggagtaaga acggattata
     1741 tagattcttg cagagttaga cataatcaag agaaagtatt tgaaatgcca tttgaatagg
     1801 gaggggggaa ctaaatatgg ctaaagtttg gatggatgca ggagaattgt tagaaaaaac
     1861 tattgatata gaagatatgt ttggatgtaa tctaagtaaa atgagaaata aaagtaaaca
     1921 aaaaggttta gttggtagaa caaattctaa aggtcaagga agaaaaagta agaaagtaga
     1981 gtgtactaac attattactg gagagagtaa aatatttgtc agtgctgtcg aagcaagtaa
     2041 atatttatat tttacagaac ttcatattgc tcgtctagca agaacaggaa agactactaa
     2101 aaatggttgg aaagttagat atattcaaga ggtgacagat ggtattggca aatgtggagc
     2161 aagtaattaa attggctgaa aagatattaa ataagaaaaa atgttctgtt aataaagcta
     2221 ttgatacagc tataaaaata ttaagtagat atgagtatga ggggatgtta gaaaaatgaa
     2281 tatattagct attacaatgc ttataatagg aagttttata gctggtagag tttatgagta
     2341 tagattgaat ctaaaagagt gtgaaaattg cgacaataaa agaggtgtat aagaatggat
     2401 gatagattag aaat
//
LOCUS       DAMJVG010000178         2414 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.184, whole genome shotgun sequence.
ACCESSION   DAMJVG010000178 DAMJVG010000000
VERSION     DAMJVG010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2414)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2414)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2414
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.184"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            102..548
                     /locus_tag="PC512_003723"
     CDS             102..548
                     /locus_tag="PC512_003723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDF2443412.1"
                     /translation="MDFKNLQYESLSYIICNLQKNFKLYCEKCLKPYKLTNGLYFYLI
                     YINKNRNCSLNDVSTEFEVDKAHTTRTISRLEQDGYIEKIQNPNDSRAFQLRVTDKGE
                     EVLGDIKNIFSKWDNHIKKEFSDTEYKELVKNLHVVKDIKTAVEEE"
     gene            550..1644
                     /locus_tag="PC512_003724"
     CDS             550..1644
                     /locus_tag="PC512_003724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH:flavin oxidoreductase"
                     /protein_id="HDF2443413.1"
                     /translation="MYCNLLKPIKIGNLELKNRVSFAPTSMGLKLEEKIKKFSDIAKS
                     GVALITLGDVSIRPSFHKVAISLSDEDGVMKYKKIVDEIHNSGAKVSAQLFCSDYDVN
                     LIKDTMNMGITSHDEIKKIMNDGVKDYITNMPKEEIKNIINLFKVTALNAKKAGFDMI
                     QIHGDRLVGSFSSSIFNNRNDEYGRTCDNRSRFASEIISSIRDEVKDIPIDYKFAIRQ
                     ENPHYGNAGVLLSEVEYFVKKFESLGVNSFHVTLANHSKLEDTIPTNNHPYFKEEGCF
                     LYLADEVKKHTNLPVCGVGKLSSPDFIESIISNNRVDMVSMSRQLLADRNWLQKVKDG
                     RVDEIKKCCYCNKKCADALQTRSQFGCILD"
     gene            1732..2262
                     /locus_tag="PC512_003725"
     CDS             1732..2262
                     /locus_tag="PC512_003725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF2443414.1"
                     /translation="MKSLVLYSSLTGNTKKIAYTIYDEIQEEKDIKDVNELVDYSIDY
                     ENYDIVFLGYWVDKGICDKNSKQVLENIHNKKIALFGTMGASKKGSYGASIIEKIESI
                     IPKDNEILGSFICQGKIAEGLKAKYKEMLKLSPDNEHIRQQLNNHEESQSHPDEQEIY
                     EASMFAKNMMIKASIV"
BASE COUNT         1005 a          235 c          424 g          750 t
ORIGIN      
        1 acatagattt agagaataaa atattcttga ctatattaat tgtttaatat aatatagttg
       61 atatagtcaa acatattata attatagaag ggaaatttaa gatggatttt aaaaatttac
      121 agtatgaaag tttgtcatat attatttgta acttgcaaaa aaactttaaa ctttattgtg
      181 aaaaatgttt aaaaccatat aaacttacga atggtctata tttctattta atttatatta
      241 ataaaaatag gaattgttct ttgaatgatg tttctacaga atttgaagtt gataaagctc
      301 atacaacaag aactatatct aggttagaac aagatggata catagaaaaa atccaaaacc
      361 ctaatgatag tagagctttt cagttgagag taacagataa gggtgaggaa gtattagggg
      421 atataaaaaa catattttca aagtgggata atcacataaa aaaagagttc tcggatacag
      481 aatataagga actggtaaag aatttacatg tggtaaagga tataaaaaca gctgtggagg
      541 aagaatagga tgtattgtaa tttattaaaa ccaattaaaa ttggaaattt ggaattaaaa
      601 aatagagtat cttttgcacc tacaagcatg ggtcttaaat tggaagaaaa aattaaaaag
      661 ttttctgata ttgctaagtc aggagtagct ctgattactc taggagatgt atctattaga
      721 cctagttttc ataaggtagc tataagccta tcggatgaag atggagtcat gaaatacaag
      781 aaaattgtag atgaaataca caattctggt gcaaaggtat cagcacaact attttgttca
      841 gattatgatg ttaatttaat taaagatact atgaatatgg gaattacttc acatgatgag
      901 ataaaaaaaa taatgaatga cggagtaaaa gattacataa caaatatgcc caaagaagaa
      961 attaaaaata ttataaattt atttaaagta acagcattga atgcaaaaaa agcaggtttt
     1021 gacatgattc aaattcatgg tgataggctt gtaggaagtt tttcatcaag tatatttaat
     1081 aatagaaatg atgaatatgg tagaacgtgt gataatagaa gtagatttgc aagcgaaata
     1141 attagtagta tccgagatga agttaaggac attccaatag actataaatt tgcaataaga
     1201 caagaaaatc ctcattatgg aaatgcagga gttttacttt cggaagttga gtattttgtt
     1261 aaaaaatttg aatccctagg tgtaaacagt tttcatgtaa cacttgcaaa tcattcaaaa
     1321 ttagaagata ctataccaac caataatcat ccttacttta aagaagaagg ctgtttttta
     1381 tatttagctg atgaagtaaa gaaacacaca aatcttccag tatgtggggt tggaaaattg
     1441 tctagcccag attttataga aagtattatt tcaaataata gagtagatat ggtttctatg
     1501 tcaagacaat tactagcaga taggaattgg ttacagaaag taaaagatgg aagagtagat
     1561 gagattaaaa agtgctgtta ttgtaataag aagtgtgcag atgctttaca aacacgctct
     1621 cagtttggat gtatactaga ttagaatatc cttataaaaa taaataattt gttaaggtta
     1681 atatattttt ggtgatttag ataagtattt agataaagag gaggagacat catgaaaagt
     1741 ttagttttat attcaagttt aactggaaat actaaaaaga ttgcttatac tatatatgat
     1801 gaaattcaag aagaaaaaga cattaaagat gtaaatgaat tagttgatta tagtattgac
     1861 tatgaaaatt atgatatagt attcttaggc tattgggtgg acaagggaat ttgtgataaa
     1921 aattcaaaac aagtgcttga aaatattcac aataaaaaga tagcactatt tggaacaatg
     1981 ggagcaagta aaaaaggaag ttatggagct agtataatag aaaagataga atcaattatc
     2041 ccaaaagata atgaaatatt aggttcattc atatgtcaag gtaagatagc agaaggattg
     2101 aaagcaaaat ataaagagat gttaaaactt tctcctgaca acgaacatat tcgccaacaa
     2161 ttaaataacc atgaggaatc tcaaagtcat ccagatgaac aagaaatata tgaagccagt
     2221 atgtttgcaa aaaatatgat gattaaagct agtattgtgt agtagttaaa caataagttc
     2281 atataagata tagaataaat aatttagtaa aaaagtatag caaataattt gctatgcttt
     2341 ttttatgaaa tcaaaaaaat aataaaaata cttgactgta aaccttgttt atacattatt
     2401 ttatagaaaa taag
//
LOCUS       DAMJVG010000179         2270 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.185, whole genome shotgun sequence.
ACCESSION   DAMJVG010000179 DAMJVG010000000
VERSION     DAMJVG010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2270)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2270)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2270
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.185"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(148..1440)
                     /gene="brnQ"
                     /locus_tag="PC512_003726"
     CDS             complement(148..1440)
                     /gene="brnQ"
                     /locus_tag="PC512_003726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HDF2443415.1"
                     /translation="MGEKQINFKDVIVIGFALFAMFFGAGNLIFPPYLGVLSGSSWLI
                     AFIGFLFADGGLALLAVIAATKFNGDTSKMFSRAGKGLSIALGCAMVICIGPLLAIPR
                     TAATTYEMGILPTIGSGISPVIFSIVFFALVLVLTIRPSKVVDIVGSILTPALLIALA
                     VLIVKGIISPLGEIRDSSLIQNVFAEGITQGYQTMDALAASVFASIIIMSVIAKGYTG
                     EKEKMKATISAGVIAVIGMALVYGGLCYLGATVSQQYGQDVQQTALIVAITAALLGTT
                     GKILLAIIVALACLTTAIGLSSAAGQYFSTLTDGKLKYEHIVIVVCVFSAIISNFGVS
                     TIIQFSSPILSMVYPATITLVILALFSNKIKNDNVFKCAAYMALLVSVLTVATSFGVK
                     IPLVNSLPFASLGFNWIVPVVIAGIIGNFIPSKSSKTA"
BASE COUNT          754 a          372 c          252 g          892 t
ORIGIN      
        1 actactccaa aaataaattt ttaaatttat caaataggat taataatgtt cttttatcta
       61 caataattta ataattcttt taaatataaa aaggaattgc ctatataatt taaaggcaat
      121 tccataatta tcaattagtt tttattatta tgcagtttta ctgcttttag atggaataaa
      181 gtttcctatt attcctgcta ttacaactgg aactatccag ttaaatccta atgaagcaaa
      241 tggtaagcta ttaactagag gaatttttac accaaaactt gttgcaactg ttaatacact
      301 tactaataat gccatgtatg cagcacattt gaacacgttg tcatttttaa ttttattact
      361 aaataatgct agtataacta gagttatagt tgctggatat accatactta gtataggaga
      421 agagaattgt attattgtac ttactccaaa gtttgatatg attgcactaa atacacaaac
      481 tactataact atatgctcat actttaattt tccatctgta agtgttgaga aatattgacc
      541 agctgctgaa gaaagaccta tagctgttgt taaacatgct aatgcaacta taatagccaa
      601 taaaatttta cctgtagttc caagtaaagc tgctgttatt gcaactatta aagctgtttg
      661 ttgaacatct tgtccatatt gttgagacac agttgctcca agataacata atccaccata
      721 aactaatgcc attcctatta ctgcaattac acctgcactt attgtggctt tcatcttttc
      781 tttctcacct gtataacctt tagctattac tgacatgatt ataattgatg caaatacact
      841 agctgccaat gcatccattg tttgataacc ttgagttata ccttctgcaa atacattttg
      901 tattaaagaa ctgtctctta tttctcctaa tggagatatg atacctttaa ctattaatac
      961 tgctaaagct ataagtaaag ctggagttaa tattgaccca actatatcta caacttttga
     1021 tggtcttatt gttaaaacca atactagagc aaagaatact atagagaata ttactgggct
     1081 tattccagaa cctattgtag gtaatatacc catttcataa gttgttgctg ctgttctagg
     1141 tattgctaaa agtggcccta tacagattac cattgcacat cctaatgcaa tacttaatcc
     1201 tttgcctgct cttgagaaca tcttcgatgt gtctccattg aacttagttg ctgctataac
     1261 tgctaataat gccaaaccac catctgcaaa aaggaatcct atgaaagcta ttagccaact
     1321 acttccagat aaaactccta gatatggagg gaagattaag ttccctgcac caaaaaacat
     1381 tgcaaatagt gcaaatccaa ttacaattac atctttaaaa ttgatttgtt tctcacccat
     1441 ttaaagcacc cccatttgaa ttttactacc ttttactaaa aaataagtcc aatctcttca
     1501 ttaaatgaaa accttttgac gagattttat ttaattatac atttttgact taaatttgtc
     1561 aattatgttt cataatttat aaaatcttca caatatttaa tacaactttc ttaattaaac
     1621 aaaatcaacc tgtatacttt aaacacagtt ggttttttgt tttttctcta atttttcttg
     1681 ataaaattaa ttattctgaa taattaaaat attaagattt tttagattat tcgatttgtt
     1741 attaagtgta ttgctttata tactgtatat atcactctcc ttttttacat tcatataatc
     1801 tttttaattc aatttaaatt ttaaatattt tgtgtttatt atataatctg aaaaaaaagc
     1861 agtcaatagc atttttaatt tttttaattt tcaaaattat gattcttaaa aaatcgtttt
     1921 ccttttgtca tagcacctat ttacgttaat tcttgtagta ttttgtattt attttgctaa
     1981 attgacagtt aactttattc gttttttatt ctatttatgt agatttgcct cttgtttttt
     2041 agtcttaaaa tcattttttc tgaaaattcc ttattatgat ttatcaactt atttttcttc
     2101 atatcaatta ctttctaact tccaacttac ttaaactttg cagttgctag tattcacgtt
     2161 tacatactta tctgtcataa ttaactaaaa attcttaata tatctctcaa tgaaaacaat
     2221 ttacccattt acttaataca tttatataat catatgtctt aaattttgtt
//
LOCUS       DAMJVG010000180         2130 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.186, whole genome shotgun sequence.
ACCESSION   DAMJVG010000180 DAMJVG010000000
VERSION     DAMJVG010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2130)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2130)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2130
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.186"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            255..869
                     /locus_tag="PC512_003727"
     CDS             255..869
                     /locus_tag="PC512_003727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HDF2443416.1"
                     /translation="MEEVIAKIITIENGFKEIENIAKKIVKNNDSKKCYYLSIYLYRS
                     EYYQVRELAVFILGFISVTISEALLFLKDNVSKDENWRVQEILAKSFDYYCSEVGYEK
                     ALPVIKEWLNSDSPNIKRAVTEGLRIWTNRDYFKSNPDVAISLLSSLKEDDSEYLRKS
                     VGNALRDISKKYPDLVKKELDSWDISNKKVEFVYKLASKCILAK"
     gene            887..1249
                     /locus_tag="PC512_003728"
     CDS             887..1249
                     /locus_tag="PC512_003728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2443417.1"
                     /translation="MKLRDEYTCPLELTHDMIKGKWKSIILWRLRIGPTSLSKLEKEI
                     NGINQKMLLEQLKELIEFGLVDKKTYEGYPLKVEYSLTPIRGKQILDALAIMQDIGIS
                     FMLDNGMEDILKEKGVLK"
     gene            1355..1852
                     /locus_tag="PC512_003729"
     CDS             1355..1852
                     /locus_tag="PC512_003729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhB/YbcL family Raf kinase inhibitor-like
                     protein"
                     /protein_id="HDF2443418.1"
                     /translation="MKVTSTGIVNGVIEDKYGKRGTQFNEGGMPTYSLPLKFEDAPKN
                     TVSFAVFLEDKDSVPVCGFAWIHWLAVNITKDELNENESVTATDFVQGTTSWHGKLGG
                     LDRLEASVYGGMAPPDRPHVYEIHVFALDTILDLEKGFYMNEFFKAIEGHVLDTFTLK
                     GSYSN"
BASE COUNT          814 a          237 c          354 g          725 t
ORIGIN      
        1 tattagtata ctcaaatcat gtaaaattta tataactcaa ttaatttttt aaatacaact
       61 ttataatata aaacttataa taaaagtaaa tttatatgtt aaatgaggtt gattttttat
      121 tattttttat ttatgctagt actaaagact tgcaaacgtt ttttgacaag tctttatttt
      181 gtctaaatta aacaaacttt tttacaaata aatacataaa atttaaacta atctatttat
      241 tggaggagat aaaattggaa gaagtaattg caaaaattat tactatagaa aatggattca
      301 aagaaattga aaacattgct aaaaaaattg taaaaaataa tgactcaaaa aagtgttatt
      361 atctatcaat ctacttatat aggtcagaat attatcaagt aagagaattg gctgtgttta
      421 tacttggttt tatatcagta actatttctg aagctttgtt atttttaaaa gataatgtga
      481 gtaaagatga aaactggaga gtacaagaaa tactagctaa atcatttgat tattattgca
      541 gtgaagtagg atatgaaaag gcacttcctg ttataaaaga atggcttaat tctgatagtc
      601 caaacataaa aagggctgtg acagaaggtc ttcgaatttg gactaataga gactatttta
      661 aatctaatcc tgacgttgct atatcactac tttctagttt aaaagaagat gatagcgaat
      721 acttgagaaa gtctgtaggt aatgctctta gagatataag taaaaaatat ccagatttag
      781 taaaaaaaga attagattca tgggatatat caaataaaaa agttgagttt gtatataagc
      841 ttgcttcaaa atgtatcttg gcaaagtaaa atggaggtga acttatttga aacttcgtga
      901 tgagtatact tgcccattag aactaacaca tgatatgata aaaggcaaat ggaaatctat
      961 tatattatgg agattacgca taggaccaac ttccttatca aaacttgaaa aggaaatcaa
     1021 tggtattaat caaaagatgt tacttgaaca acttaaagaa ttaattgaat ttggtcttgt
     1081 agataaaaag acatatgaag gttacccact taaagtcgaa tactcactta cacctattcg
     1141 agggaaacaa atattggatg ctttggctat aatgcaagat ataggaatta gctttatgtt
     1201 ggataatggt atggaagata ttcttaagga aaaaggtgtt ttaaaataaa tagataccca
     1261 caaaaaagta agtaatttac cattattttc aactggtata taattaaatt atagatatat
     1321 tctattaatt tattataata ggaggtaaat tattatgaaa gtaactagta caggtatagt
     1381 aaatggtgtt atagaagata aatatggtaa aagaggaact cagttcaatg aaggtggtat
     1441 gcctacatat tcactacctc taaagtttga agatgctcca aagaatacag tatcctttgc
     1501 tgtattttta gaagataaag actctgttcc tgtatgtggg tttgcatgga tacattggtt
     1561 agctgtaaat ataacaaaag atgagttaaa tgaaaatgaa agtgtaacag ctactgattt
     1621 tgtacaaggg actactagtt ggcatggtaa actaggaggt cttgacagat tagaggccag
     1681 tgtatatggt ggaatggctc ctccagacag acctcatgtc tatgaaatac atgtatttgc
     1741 acttgatact atccttgacc ttgaaaaagg attctatatg aatgaatttt tcaaagctat
     1801 tgaagggcat gttttagata catttacact aaaaggaagt tattctaatt aattaggttg
     1861 actatagcta atcattaatt aaatgataca tttaattgat gattagctta attgttatta
     1921 gaatattttc tgcactttat cttaatatat attttagttg actggtattt taatttctat
     1981 tagattatta tcaatttata taaattgatt aaaaaatagc tacgcacact cgtgacttta
     2041 gtcatgagtt agtagctaaa atagtcagca tatagggaaa cttatatgta gagataggat
     2101 agaacctatc caatactact tgaattgcta
//
LOCUS       DAMJVG010000181         1986 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.187, whole genome shotgun sequence.
ACCESSION   DAMJVG010000181 DAMJVG010000000
VERSION     DAMJVG010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1986)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1986)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1986
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.187"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            84..200
                     /gene="rrf"
                     /locus_tag="PC512_003730"
     rRNA            84..200
                     /gene="rrf"
                     /locus_tag="PC512_003730"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            207..281
                     /locus_tag="PC512_003731"
     tRNA            207..281
                     /locus_tag="PC512_003731"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:239..241,aa:Asn,seq:gtt)
     gene            286..360
                     /locus_tag="PC512_003732"
     tRNA            286..360
                     /locus_tag="PC512_003732"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:319..321,aa:Glu,seq:ttc)
     gene            366..441
                     /locus_tag="PC512_003733"
     tRNA            366..441
                     /locus_tag="PC512_003733"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:399..401,aa:Val,seq:tac)
     gene            447..523
                     /locus_tag="PC512_003734"
     tRNA            447..523
                     /locus_tag="PC512_003734"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:481..483,aa:Asp,seq:gtc)
     gene            534..608
                     /locus_tag="PC512_003735"
     tRNA            534..608
                     /locus_tag="PC512_003735"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:566..568,aa:Thr,seq:tgt)
     gene            623..707
                     /locus_tag="PC512_003736"
     tRNA            623..707
                     /locus_tag="PC512_003736"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:657..659,aa:Tyr,seq:gta)
     gene            717..790
                     /locus_tag="PC512_003737"
     tRNA            717..790
                     /locus_tag="PC512_003737"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:749..751,aa:Gly,seq:tcc)
     gene            801..877
                     /locus_tag="PC512_003738"
     tRNA            801..877
                     /locus_tag="PC512_003738"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:835..837,aa:Arg,seq:tct)
     gene            887..962
                     /locus_tag="PC512_003739"
     tRNA            887..962
                     /locus_tag="PC512_003739"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:920..922,aa:Gln,seq:ttg)
     gene            974..1049
                     /locus_tag="PC512_003740"
     tRNA            974..1049
                     /locus_tag="PC512_003740"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1007..1009,aa:Lys,seq:ttt)
     gene            1052..1140
                     /locus_tag="PC512_003741"
     tRNA            1052..1140
                     /locus_tag="PC512_003741"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1086..1088,aa:Ser,seq:tga)
     gene            1158..1248
                     /locus_tag="PC512_003742"
     tRNA            1158..1248
                     /locus_tag="PC512_003742"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1192..1194,aa:Ser,seq:gct)
     gene            1257..1333
                     /locus_tag="PC512_003743"
     tRNA            1257..1333
                     /locus_tag="PC512_003743"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1291..1293,aa:Pro,seq:tgg)
     gene            1419..1494
                     /locus_tag="PC512_003744"
     tRNA            1419..1494
                     /locus_tag="PC512_003744"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1452..1454,aa:Trp,seq:cca)
     gene            1555..1631
                     /locus_tag="PC512_003745"
     tRNA            1555..1631
                     /locus_tag="PC512_003745"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1589..1591,aa:Pro,seq:tgg)
     gene            1638..1714
                     /locus_tag="PC512_003746"
     tRNA            1638..1714
                     /locus_tag="PC512_003746"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1672..1674,aa:Ile,seq:gat)
     gene            1718..1793
                     /locus_tag="PC512_003747"
     tRNA            1718..1793
                     /locus_tag="PC512_003747"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1751..1753,aa:Phe,seq:gaa)
     gene            1801..1877
                     /locus_tag="PC512_003748"
     tRNA            1801..1877
                     /locus_tag="PC512_003748"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1835..1837,aa:Met,seq:cat)
BASE COUNT          517 a          452 c          531 g          486 t
ORIGIN      
        1 taactctaaa aaaaaataaa aaaagtattg acaaaaatag taaaaaatgt taatattata
       61 cttgtcctag caacaagaaa aaatgtggtt ataatagcgg aggagataca cctgtttcca
      121 ttccgaacac agaagttaag ttctctagcg ctgatggtac ttggtgggaa actgcctggg
      181 agagtaggac atagccacgt gaatgttcca aggtagctca acggtggagc aaccggctgt
      241 taaccggtag gctgtgggtt cgagccccac ccttggagcc attatggctc gttggtcaag
      301 aggttaagac accgcccttt cacggcggta acaggggttc aattccccta cgagtcacca
      361 tttgtgggat catagctcag ctgggagagc acctgcctta caagcagggg gtcacaggtt
      421 cgagccctgt tggtcccacc atttgcggcc tggtagttca gttggttaga atgccagcct
      481 gtcacgctgg aggtcgaggg ttcgagcccc ttccaggtcg ccaaaataaa aatgctggtg
      541 tggctcaacg gtagagcagc tgacttgtaa tcagcaggtt gtaggttcga ttcctatcac
      601 cagctccatg taaaactaat acggaggatt tcccgagcgg ccaaaggggg cagactgtaa
      661 atctgttgtc atcgacttcg gtggttcgaa tccaccatcc tccaccaatt aaatatgcgg
      721 gtgtagctca atggtagagt tctggccttc caagccagct gtgagggttc gatccccttc
      781 acccgctcca aagaaagcgt gggtgcatag ctcagctgga tagagcaacg cccttctaag
      841 gcgtgtgtcc ggggttcgaa tccctgtgcg ctcaccacat atatattggg gattagccaa
      901 gtcggtaagg cacatgactt tgactcatgt atgcgtaggt tcgagtcctg catccccagc
      961 caaataaaaa tatggtctat tagctcagtc ggtagagcac ctgactttta atcagggtgt
     1021 cccgcgttcg agtcgcggat agatcaccaa tggagaggtg tccgagtggt ttaaggagct
     1081 ggtcttgaaa accagtgact tcgaaagggg ccgtgggttc gaatcccacc ctctccgcca
     1141 aaaaaatgac tgaatttgga gaagtactca agtggctcaa gaggatcccc tgctaaggga
     1201 ttaggctggg taaccggtgc gagggttcga atccctcctt ctccgccatt caaaaacgag
     1261 gtgtagcgca gtttggtagc gcacatggtt tgggaccatg gggccggggg ttcgagtccc
     1321 ttcacctcga ccaacttaag cttttagttc agttggttag agtgcccaac tcatggctag
     1381 taattctagg gtttgagtcc atgaaggtta ttcttcatag gggtgtagct cagttggtag
     1441 agcgtcggtc tccaaaaccg tgcgccgggg gttcgagtcc ctccacccct gccaaataaa
     1501 aaggacttga aaaaagttgg attttagagt agtataagat agtaaataag atttcgaggt
     1561 gtagcgcagt ttggtagcgc acatggtttg ggaccatggg gccgggggtt cgagtccctt
     1621 cacctcgacc aagaaaaggg cctatagctc aggtggttag agcgcacgcc tgataagcgt
     1681 gaggtcgctg gttcgagtcc agctaggccc accatttgcc cagatagctc agtcggtaga
     1741 gcaggggact gaaaatcccc gtgtcggtgg ttcgattccg cctctgggca ccaggaatac
     1801 ggcggtatag cttagttggc tagagcgttc ggttcatacc cgaaaggtca taggttcgac
     1861 tcctattacc gctaccatct aactatatca ataaagaact ttgaaaatta aacagtaggt
     1921 taatttataa acaagaaaca aaccataaag ccagatattt tgataacaat agtatctgag
     1981 cctgat
//
LOCUS       DAMJVG010000182         1904 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.188, whole genome shotgun sequence.
ACCESSION   DAMJVG010000182 DAMJVG010000000
VERSION     DAMJVG010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1904)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1904)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1904
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.188"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            155..349
                     /locus_tag="PC512_003749"
     CDS             155..349
                     /locus_tag="PC512_003749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase"
                     /protein_id="HDF2443419.1"
                     /translation="MSVIVMCSRCGKEIDKYRNKYITYYEKNTNAEIKVCINCALDLL
                     EKTRENQELNIQEFQDTIIL"
     gene            complement(451..960)
                     /gene="vanZ1"
                     /locus_tag="PC512_003750"
     CDS             complement(451..960)
                     /gene="vanZ1"
                     /locus_tag="PC512_003750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ1"
                     /protein_id="HDF2443420.1"
                     /translation="MKSRKHNITKGLFIVYIIILTWIILFKLQFDISSLETMNLRSIN
                     LVPFAGSLIINNRVDISEIILNVAIFVPFGIYVCMLKEEWSFIKKVIPIFITSLAFET
                     LQYIFALGASDITDLIGNTLGGIIGIAVFMLLSKIFKNNTIKIINVLALIVTIIVVLF
                     LGLVIFANL"
     gene            complement(1280..1669)
                     /locus_tag="PC512_003751"
     CDS             complement(1280..1669)
                     /locus_tag="PC512_003751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2443421.1"
                     /translation="MKINKLPHAELKLMKYIWGVDDVLASRDIIEDMKLKYDWKKSTT
                     LTFLKNLVDKGFLTTDKVDRCTHYTIAIKEKDYLKVETKSFFSFMHNNSFKSFISALH
                     DDEVLDSKSLDKLEEYFKNLKEGDIDD"
BASE COUNT          702 a          262 c          192 g          748 t
ORIGIN      
        1 ctataaatat tttacctata acctttattt ttttattaaa atgcattata ataaaaagta
       61 aatctaaatt tgatacagtt ttaacaatca ttattttcag aaaagtgata ctattgaata
      121 tattaagaat aattagagat ggaggaacta agatatgagc gtaattgtaa tgtgtagtcg
      181 ttgtggaaaa gaaatagata aatatagaaa taaatatata acttattatg agaaaaatac
      241 caatgcagaa attaaagttt gtataaattg tgcgttagat ttattagaaa aaacaagaga
      301 aaatcaagaa ttgaacatac aagagtttca agatacaata attctttaat aatttaggaa
      361 agcacctgta taggtgcttt ttatgtgtaa ataattttat atgtaactgt atcttacgtt
      421 ctattttaag ctaaacatat atacttattt ctataagttt gcaaaaataa ctaatcctaa
      481 aaataataca acaataattg tcacaatcaa tgccaataca ttgataattt ttatggtatt
      541 attcttaaat attttcgata atagcataaa aacagctatt cctatgattc ctcctagtgt
      601 gtttcctatc aaatccgtta tatcacttgc acctagtgca aatatatatt gaagtgtttc
      661 aaatgccaaa ctagttataa aaataggtat aacttttttt ataaagctcc attcttcttt
      721 tagcatacac acatatatcc caaatggtac aaatatagcc acatttaata taatctctga
      781 tatatctact ctattattaa ttataagtga cccagcaaaa ggtactaagt ttatgcttct
      841 aagattcatg gtttcaaggg atgaaatatc aaattgcaac ttgaatagta ttatccatgt
      901 taaaataatt atgtaaacta taaataatcc ttttgtaata ttatgttttc tagatttcat
      961 ttattacctc cttactatat cattgtatta ttttattaat acaatgatat agtaaggtaa
     1021 tttatctgtc aactatttct tctaaaatta tattcctttt ataatttcaa tatctttatc
     1081 atatttacat gatttaagct attgtagtat ttcatatatc tttaaatttt aattggtatt
     1141 attctctata ttttttacta tcaaacacta aggaaataat cacttttctt tatataatgt
     1201 tctaccatca cataaaacta acattaaatc aaaacgctac tctcaattgt ctcaaactaa
     1261 aaagatactg ataactttat tagtcatcaa tatctccttc tttcaaattt ttaaagtatt
     1321 cttctaactt gtccaagctc ttactatcta aaacttcatc atcatgtaat gctgaaataa
     1381 aactcttaaa tgaattgtta tgcataaaac taaaaaaact ctttgtctca acttttaagt
     1441 aatctttctc ttttatagct atagtataat gcgtacatct atctacctta tcagtagtta
     1501 aaaagccctt atctactaaa ttttttaaaa atgtcaatgt tgtgctcttt ttccaatcgt
     1561 atttcaactt catgtcttct atgatatctc ttgaggctaa tacatcatct actccccaaa
     1621 tatacttcat tagttttagt tctgcatgtg gtaatttatt aatcttcatt agtttacacc
     1681 tcttaccaat ttatgtataa ctaaacttta taacaataag tgtatataat caattagatt
     1741 ggaataaata taaattccaa tttattctat ataaaaataa ttaataaaaa agaagtactc
     1801 tactttagag agtacttttg gattatatat tcaaaaattt atctaacatg attagagtat
     1861 gttttatgct ttagtgtgat aattttagtt cgttttatta ttat
//
LOCUS       DAMJVG010000183         1853 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.189, whole genome shotgun sequence.
ACCESSION   DAMJVG010000183 DAMJVG010000000
VERSION     DAMJVG010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1853)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1853)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1853
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.189"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            105..389
                     /locus_tag="PC512_003752"
     CDS             105..389
                     /locus_tag="PC512_003752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443422.1"
                     /translation="MLVYNKSFYPNDIFPRLDFSKIKKQLKLIDNDLSDFGSICIIEK
                     EHYTISVNSIGEINVYYDLEYENKVYRIVYEIEKLFKSQVGRFSISTYRN"
     gene            complement(546..719)
                     /locus_tag="PC512_003753"
     CDS             complement(546..719)
                     /locus_tag="PC512_003753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase"
                     /protein_id="HDF2443423.1"
                     /translation="MKRKLSTYFKGYILGLCIAFLLFTFILKKLIIENIIGIIIGTGI
                     AFLLIYLFNKKRK"
     gene            complement(1160..1375)
                     /locus_tag="PC512_003754"
     CDS             complement(1160..1375)
                     /locus_tag="PC512_003754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2443424.1"
                     /translation="MAIVVNLDVMMAKRKISLKELAEKIDITNANLSILKTGKAKAIR
                     FTTLNEICKALDCQPGDILEYVEDEND"
     gene            complement(1386..1853)
                     /locus_tag="PC512_003755"
     CDS             complement(1386..1853)
                     /locus_tag="PC512_003755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HDF2443425.1"
                     /translation="MITKFFSNILSVFLYFLLSLLGVAGIIFLCMIPMFLYDFSSDKV
                     IALIARILYFSDYFIVILFLIFIINSTKYSPFVLENVKRFKVMGFCLLINTIIECING
                     YNLNTNNIRIFGTDSGGISPLMVISFIFALMCFVIAETFDKAIKIKEDNDLTI"
BASE COUNT          750 a          197 c          232 g          674 t
ORIGIN      
        1 attttgtttt atataaagta atttgaaaaa tatggaaaaa ttgattagta cattattaat
       61 tagggtataa aatggtgtaa atagaatgat aaggggtgga tgaaatgctt gtatataata
      121 aaagttttta tcctaatgac atatttccaa gattagattt ttcaaaaata aaaaaacagt
      181 taaaattgat agataatgac ctgtcagatt ttggaagcat atgtataata gaaaaagaac
      241 attatacgat aagtgtaaac agtataggtg aaataaatgt gtactatgat ttagagtacg
      301 aaaataaggt gtatagaata gtttatgaga ttgaaaagtt atttaaatct caagttggaa
      361 ggtttagcat atctacatac agaaattgat aattaaaaaa gtagaaatta aaaaacttaa
      421 tactaaagat atagataaat atatgaggta acagctagag agagttgtta ccctttttaa
      481 atactaagta tatattattc ttattaattt tttgtaaatt cactaaaaga cctttttata
      541 gaatattatt ttcttttttt attaaatagg taaatcagta aaaatgcaat tccagttcca
      601 attattattc caatgatatt ttctataatt aattttttta atataaaagt aaataataaa
      661 aatgctatac ataaacctaa aatatatcct ttaaaatagg ttgaaagttt tcttttcata
      721 taatcaccaa cttgtatcag atttagttta cttaattaga gtataacagt gttgtaactt
      781 caaagagtat ctaaaagatt acaaatgtta gataaaatca tcaataatgt aatttataac
      841 acatagctat aagctatgca ataatataaa tggaggtata agtaaatgaa aaagttccat
      901 gttttgctaa cagtttaaat aaatattatg tagaaaagaa tgtatatagg aatctgtggt
      961 aaaattatca atttaaaagt attatttagt gtgatacagt tcttataggt aatggataac
     1021 aaatagataa aggaacagtt tctttcttag aacatatttt gttatgactt taaacaaagt
     1081 taatattaat gtcaataata tagtaaaaga ataaaaatca tatagtataa taaaaaagag
     1141 tgtttctaaa cactcttttt taatcatttt catcttctac atattcaagt atatcacctg
     1201 gctgacagtc taaagctttg caaatttcgt ttagagtggt aaatctaata gcttttgctt
     1261 ttccagtttt taaaattgat aaatttgcat ttgtaatatc tattttttct gccaattctt
     1321 taagtgatat ttttcttttt gccatcatta catctaggtt aactactatt gccataacat
     1381 cacctctata tcgttaaatc attatcttct tttattttta tagctttatc aaatgtttct
     1441 gcaattacaa agcacattag tgcaaatata aaagagataa ccataagtgg tgagataccg
     1501 ccactatcag ttccaaaaat tcttatatta ttagtattta aattataacc attgatacat
     1561 tcaattatag tgtttatcaa taaacaaaat cccattactt taaacctttt tacattttca
     1621 agtacgaatg gggaatactt agtactatta attataaata tcaagaataa gatgactata
     1681 aagtagtcag aaaaatatag tattcttgca attaaagcaa ttactttgtc agaactaaaa
     1741 tcatataaaa acataggtat catacataag aatattatac cagcaactcc taaaagtgat
     1801 aatagaaaat atagaaatac tgataatata ttactaaaaa attttgtaat cat
//
LOCUS       DAMJVG010000184         1817 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.190, whole genome shotgun sequence.
ACCESSION   DAMJVG010000184 DAMJVG010000000
VERSION     DAMJVG010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1817)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1817)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1817
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.190"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            126..473
                     /locus_tag="PC512_003756"
     CDS             126..473
                     /locus_tag="PC512_003756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HDF2443426.1"
                     /translation="MHENKKNLLDGSLAQYNDTAVPKIPVFAGNDITSEVYYFKPNQV
                     LNAHRHPNGEQIFVFLKGEGKMKLGEHECDVKNGDTVFVPTGEWHEITNGSNEEMVAV
                     QITKINAGAEYRG"
     gene            complement(623..1672)
                     /locus_tag="PC512_003757"
     CDS             complement(623..1672)
                     /locus_tag="PC512_003757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2443427.1"
                     /translation="MFKKIVAIASSIIVSTICLTGCDFNSNDKKDESSSSKNLDKVTI
                     AEVTHSVFYAPQYAAITKGFFEDEGIKIDLINTQGADKTMAALISGEANVGLMGPEAS
                     IYVYNQNKNDYAVNFAQLTKRDGSFLVARKKMPNFSYNDLKGTEILGGRKGGVPLMTF
                     EYVLKEKGLTIGENLKAGNVNVRTDVQFGVMAGAFAGGEGDFTTAFEPTATAMEKEGS
                     GYIVTSIGKDSGEIPFTAYSTTRSYMKNNKDLIQRFTNAVYKGQLWIQQASSKEVAKA
                     MQPFFEDISLEDLTTVVDRYKSIDAWSQNPVLKEEGLKKLMTVMKEAKELDKEAPYKD
                     IVNTEFANNAIKNIK"
BASE COUNT          616 a          281 c          245 g          675 t
ORIGIN      
        1 aatagtatta tacttatatt taaaaataaa agaattttat tcctattgtg taaagtgaga
       61 atactatttt cttatattgg tataataata gtaaatctat aatatagaaa agaggtattt
      121 ctagtatgca tgaaaataaa aaaaatctat tagacggaag cttagctcaa tataatgata
      181 cagcagttcc aaaaatacca gtatttgctg gtaacgatat aacttcagaa gtttattatt
      241 ttaaacctaa tcaagttctt aatgctcata gacaccctaa tggtgaacaa atatttgtgt
      301 tcctaaaagg agaaggtaaa atgaaacttg gtgagcatga atgtgatgta aaaaacggag
      361 atactgtatt tgtaccaaca ggagagtggc atgaaattac taatggaagc aatgaagaaa
      421 tggtagccgt tcaaattaca aaaattaatg ctggagcaga atacagagga tagatatata
      481 agtacagtta gtactttaat atctatttta ttatataaac tttaatctca aatataaaaa
      541 gagtctttta aaaggctctt tttatatttt tgttaatttt cattataaaa acaagaaaat
      601 atctagctaa aactaatata ttttatttaa tattttttat agcattgttt gcaaactcag
      661 tatttacgat atctttataa ggtgcttcct tatctagttc tttagcttct ttcataacag
      721 tcatcaattt cttcaaacct tcctctttta atacaggatt ttgagaccat gcatctattg
      781 atttatatct atctacaact gttgttaaat cttctaaaga tatatcttca aagaaaggtt
      841 gcatagcctt agctacttct ttgctagatg cttgttgaat ccataattga cctttataaa
      901 cagcatttgt aaatctttga attaaatctt tattgttttt catgtatgat ctcgtagtag
      961 agtatgctgt aaaaggtatt tctccagaat cttttcctat agatgtaact atatatccac
     1021 taccttcttt ttccattgct gttgctgtag gttcaaatgc tgttgtaaag tcaccctctc
     1081 cacctgcaaa agctccagcc attacaccaa attgtacatc agttcttaca ttaacattgc
     1141 ctgcttttag attttctcca atagtaagac ctttttcttt tagaacatat tcaaaagtca
     1201 ttagtggaac tccacctttt ctaccaccta atatttcggt tccttttaaa tcattgtaag
     1261 agaaattagg catttttttc ctagcaacta gaaaactacc atctcttttt gtcaattgag
     1321 caaagttcac tgcataatcg tttttgtttt gattatatac atatatagat gcttcaggac
     1381 ccattaaacc tacgtttgct tcacctgaaa tcaaagctgc catagtttta tctgcacctt
     1441 gggtatttat aaggtcaatc tttatacctt catcttcaaa gaatcctttc gtaatagcag
     1501 catactgtgg agcataaaaa acagagtgag taacttctgc tatagttact ttatccagat
     1561 ttttagacga agaagattca tcttttttgt cattagagtt aaaatcacat ccagttagac
     1621 atattgtact tacaatgata gagcttgcta ttgcgactat ttttttaaac ataataaata
     1681 cctcccataa gacatacgaa tagtatatag tattaaatat ttattgtagt tgttacaaaa
     1741 atgtatctat acttataata tttctacaaa aacttaataa taattttcag ttttatgttt
     1801 agttttttca gtaatgt
//
LOCUS       DAMJVG010000185         1805 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.191, whole genome shotgun sequence.
ACCESSION   DAMJVG010000185 DAMJVG010000000
VERSION     DAMJVG010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1805)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1805)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1805
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.191"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(<1..92)
                     /locus_tag="PC512_003758"
     CDS             complement(<1..92)
                     /locus_tag="PC512_003758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011058338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443428.1"
                     /translation="MKDKWILCPVCGNKTRLKIRADTELKNFPL"
     gene            complement(131..418)
                     /locus_tag="PC512_003759"
     CDS             complement(131..418)
                     /locus_tag="PC512_003759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443429.1"
                     /translation="MSTLIIGFIVAGVLLIAEYLLCTKFRSPLWGGIIPLLILAGTIY
                     VFASGRIPFERPYIFPFVVVNTLFFGDWGTGRDKYKKIKQTEMEKMKAKDI"
     gene            complement(421..717)
                     /locus_tag="PC512_003760"
     CDS             complement(421..717)
                     /locus_tag="PC512_003760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009460866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2089 family protein"
                     /protein_id="HDF2443430.1"
                     /translation="MELDKIPQWILALEQEDATFLKNFALKSGSLKEIAKMYGVSYPT
                     VRLRLDKLIQKIEMCDQQEEEPFQTFIKGLAVDSRIDVETAKIIIEKYKKEKEK"
     gene            complement(806..1711)
                     /locus_tag="PC512_003761"
     CDS             complement(806..1711)
                     /locus_tag="PC512_003761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDF2443431.1"
                     /translation="MFKKNKKQTENVKEKKVRTVKVGTHKKSVIALWVVLIASVSFGV
                     YKNFTAIDMHTVHETETIQLRLTDTNGIENFVKNFAKSYYTWNNSKEAIEARTQAISG
                     YLTKELQALNTDTIRKDIPVSSAVNGVQIWSVTQADENQFSVIFTVEQLITENGSTKT
                     VRSAYEVTVYVDGSGNMVLTKNPTITSIPVKSGYTPKAKESDGTVDAVTTDEINEFLT
                     TFFKLYPTATAKELSYYVNEGVLKPIGKDYVFSELVNPIYNRIDSQVTVSVAVKYLDQ
                     QTKATQVSQFDLVLEKSGSNWKIIK"
BASE COUNT          485 a          397 c          300 g          623 t
ORIGIN      
        1 aatagtggga aatttttaag ctctgtgtcc gctctaattt tcaacctcgt tttattaccg
       61 caaactggac ataaaatcca tttatctttc aataatgcgt tcctcctatc taagtataca
      121 gttttgtaat ttatatatct ttagctttca tcttttccat ttcagtttgc tttatctttt
      181 tatatttatc cctgccagta ccccaatctc caaaaaataa agtattgact acaacaaacg
      241 ggaaaatata tggtctttca aatggtattc tgccacttgc aaaaacatat attgttcctg
      301 ccaagataag caagggaata atacctcccc aaagaggact tctaaatttt gtgcagagaa
      361 gatactctgc aattaataaa actcctgcaa caataaagcc aataattaat gtactcatgg
      421 ttatttctcc ttttcttttt tatatttttc aataattatc tttgcagttt ccacgtcaat
      481 tcgagaatca accgctaacc ctttaataaa agtttggaaa ggttcttctt cctgctggtc
      541 gcacatttca attttttgaa ttaatttgtc taaacgtaat cgaacagtag ggtaagatac
      601 cccatacatt ttcgctattt cctttaatga accggattta agtgcgaagt ttttaagaaa
      661 agtagcgtcc tcttgctcta aggcaagaat ccattgaggg attttatcaa gctccaaaaa
      721 cacaactcct ttcatattat ctttaacaat attcagtata tcataaataa aattaaagtc
      781 aataagaatt taaacatcaa aataattatt ttataatctt ccagttgctc ccgctttttt
      841 ccagcaccaa atcaaattgt gatacctgcg ttgcctttgt ctgctggtcg aggtacttca
      901 cagccacgga aaccgtcact tgactgtcga tgcggttgta gatgggattt accagttccg
      961 agaatacata atctttcccg ataggcttta acacgccctc atttacataa taggacagct
     1021 ctttagcggt tgcggttggg tagagcttaa agaacgtcgt cagaaattcg ttgatttcgt
     1081 ccgtcgtcac agcgtccacc gttccgtcgc tttcctttgc ctttggcgtg tagccggatt
     1141 tcacgggtat gctggtaatg gtcggattct tcgtgagaac catgtttcca gagccatcca
     1201 catagaccgt gacttcatag gcggagcgta ccgtcttcgt gcttccattc tccgtgatta
     1261 actgttccac agtgaagatc acggagaact ggttttcatc cgcctgcgtg acagaccata
     1321 tctgtacccc attgaccgcc gaagacactg gaatatcctt gcggatggta tcggtattaa
     1381 gtgcctgcaa ttcctttgtc agataaccgc tgattgcctg cgtccttgct tcaatagctt
     1441 ctttgctgtt attccatgtg taataggact tcgcaaagtt cttcacgaaa ttttcaatcc
     1501 cgttggtatc ggtaagtctt aactgtatgg tttctgtttc atgtacggtg tgcatatcaa
     1561 tagcggtaaa attcttatat accccaaaac tcacgcttgc gataagcact acccacaatg
     1621 caatcacaga ttttttatgt gtaccgactt tcacagtacg cactttcttt tctttgacat
     1681 tctctgtctg tttcttattc ttcttaaaca tattttctaa gtcctttctt ttattttact
     1741 cgtcctgcac cgattaagtg ttgttgccag taactattat ttaagtctgc atatcctatc
     1801 ggatt
//
LOCUS       DAMJVG010000186         1624 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.192, whole genome shotgun sequence.
ACCESSION   DAMJVG010000186 DAMJVG010000000
VERSION     DAMJVG010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1624)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1624)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1624
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.192"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            109..582
                     /locus_tag="PC512_003762"
     CDS             109..582
                     /locus_tag="PC512_003762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2443432.1"
                     /translation="MFKEYLIRELKEDDIKNALDLIWNVFEEFESPDYCDEGITTFHQ
                     FIEYNSIIEKIKEKTLFFWGCFDSKKLIGVLAIRNLNHICMLFVDKNYHKHGVAKKLM
                     TTGIQYCICNKFNLTEITVNSSPYAVEVYHKLGFKDTAVEQIVDGIRFTPMKLLI"
     gene            complement(951..1508)
                     /locus_tag="PC512_003763"
     CDS             complement(951..1508)
                     /locus_tag="PC512_003763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2443433.1"
                     /translation="MRVSREIVIQATSDIVNKDGLNKVSLKVIAEKLGIRTPSLYNHI
                     ESLDDLLLEVAHKGMREMNSQMIKAAIGNFGDTAIKCISIAYFNFIISNPGVYETIQW
                     ATWHGNNETLEIFDEYKSLLEKLILSCNLNTKNTGEVLNLIMSVLHGYSTLQLGKSFL
                     SKEEAIKGLVDSIDTVLLGIHKKYD"
BASE COUNT          596 a          214 c          170 g          644 t
ORIGIN      
        1 aattatatat tatcataata ttctaaattt ataaaacaaa ttgtattgaa ttgaatttat
       61 ttaagatata taattataat taaaataata ataaaggtgt tgtttataat gttcaaagaa
      121 tacttaataa gagaattaaa agaagatgat attaaaaatg cattagactt aatctggaac
      181 gtatttgaag aatttgaatc tccagattat tgtgatgaag gaattacgac atttcatcaa
      241 tttatagaat ataactctat tattgaaaaa atcaaagaaa aaactctctt cttttggggt
      301 tgttttgact ctaaaaaact tattggagtc ttagctatta gaaatttaaa tcatatatgt
      361 atgttatttg tagataaaaa ctatcataaa catggtgttg caaaaaaatt aatgactaca
      421 ggcatacaat actgtatttg taataaattt aatttaactg aaataactgt aaattcatca
      481 ccttatgctg ttgaagttta tcataaatta ggatttaaag atactgctgt tgagcaaatt
      541 gttgacggta tacgttttac acctatgaaa ttgttaatat aataaattaa ataaaaagca
      601 aagtctctta aatattttat agttactttg cttttaaacc aagatttaaa ataatactat
      661 cttttttgtt ttttaataat atactttaaa atccttacta atatgaacta taatttattt
      721 tttgatatcc tttttgatta acatataaat taattcaatt attaaacata aactatgttg
      781 tttctcttta tatctcttct ttgtaaacaa tattgggcat ttgaaaataa atattcttaa
      841 aatatactgt tctcctgttg attttccttt ggtacaaatg ataaaaattt aatttacatg
      901 ccccataatg aagtgttcaa taaataagtt aaaataattt atttacctcc ttaatcatat
      961 tttttatgaa tacctaataa cacagtatca atagaatcga ctaaaccttt tatagcttct
     1021 tctttactca aaaatgattt cccaagttgc aaagtcgaat aaccatgaag tacactcatt
     1081 attaagttta atacttcacc tgtattcttt gtatttagat tacaagaaag aataagtttt
     1141 tctaataagg atttatattc atcaaagatt tctaatgttt cattatttcc atgccaagta
     1201 gcccactgaa ttgtttcata aacaccagga ttagaaatta taaaattaaa gtatgctata
     1261 cttatacact ttatagctgt atctccaaaa tttccaatag ccgcctttat catttgacta
     1321 ttcatctctc tcattccttt atgagctact tcaagtaata aatcatctag actttctata
     1381 tgattgtaca aagatggtgt acgtattcct agcttttctg caataacttt taaagaaact
     1441 ttgttaagcc catctttatt aactatatct gatgtagctt gtataactat ttctctacta
     1501 acacgcatga ttttccctct ttcatttaaa attaattact ttattagttt aactaatcta
     1561 attagtttcg tcaattattg taatttataa aattctttat actattataa aatcttgaca
     1621 gttt
//
LOCUS       DAMJVG010000187         1604 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.193, whole genome shotgun sequence.
ACCESSION   DAMJVG010000187 DAMJVG010000000
VERSION     DAMJVG010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1604
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.193"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            178..378
                     /locus_tag="PC512_003764"
     CDS             178..378
                     /locus_tag="PC512_003764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003723180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDF2443434.1"
                     /translation="MNNGIVKWFNNEKGFGFISMEGRDDVFAHFSAIQTSGFKSLEEG
                     QQVSFDIVKGARGPQAENITIL"
     gene            complement(542..754)
                     /locus_tag="PC512_003765"
     CDS             complement(542..754)
                     /locus_tag="PC512_003765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443435.1"
                     /translation="MVCKIFITLKTILPKTQIIVTTHSPHILQIDSKEEMIVLDMAES
                     DNVYKKELKLGEYGVLGWTNEGLYLH"
     gene            1129..1311
                     /locus_tag="PC512_003766"
     CDS             1129..1311
                     /locus_tag="PC512_003766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HDF2443436.1"
                     /translation="MFKFYNNATLMFLPGTNIKTISERLGHADIKITMNSYSQFLEEM
                     DREAFENLSKILFIVF"
     gene            1382..>1604
                     /locus_tag="PC512_003767"
     CDS             1382..>1604
                     /locus_tag="PC512_003767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443437.1"
                     /translation="MNIIKSITLLLTLLIVILMTGCSPRESASEVAKKYIDKMNSGDY
                     ETAYSLLSKDSKKKISIENLEEFQNILVST"
BASE COUNT          619 a          190 c          217 g          578 t
ORIGIN      
        1 attaatatat agcaatgtaa aacgtttaaa tatattttta atattaagaa taattaaaat
       61 gttaactaaa aaatataatt aagtagacat ttctattaat ctatgataca atagtatttg
      121 tggtaataca caattaaatc aagtatatct tgatataggt taataggagt atttttaatg
      181 aataatggaa tagtgaaatg gtttaataat gaaaaaggat tcggttttat atcaatggaa
      241 ggtagagatg atgtgtttgc tcatttctca gctatacaaa cttcaggatt taaatcatta
      301 gaagaaggtc aacaagtaag ctttgatata gttaaaggtg ctagaggtcc tcaagcagaa
      361 aatataacta tattataata tatagatttt tcgggaaaga ctctttttag agtctttttt
      421 tattgttaat atatgtaaga taatcattgg tgaagtaaat aaggtatatt gagtaatgtt
      481 cttgatagtt tatatgctaa tgaatttcaa aaaaataagc actcctataa aaagagtgct
      541 cttaatgtaa atataaacct tcattggtcc agcctaatac cccgtattct ccaagtttta
      601 actctttttt atatacatta tcactttcag ccatatctaa cacaatcatt tcttctttag
      661 aatcaatttg taaaatatga ggactgtgtg ttgtgacaat tatttgtgtt tttgggagaa
      721 ttgtttttaa tgtaataaaa attttacata ccacatagtt gatataaaac ttaagactag
      781 cagactcata agcaattagt tgcctctctt tacataccac atagttgata taaaacctag
      841 aggctctcag agaagttata agatgtttag taactttaca taccacatag ttgatataaa
      901 actccaaaat aaacttagca tctccaatgt ttacacatat acaatgctct taaaattgca
      961 gtgaacgcgc aatattgcaa ttgataatac ttatcatata ttctcaatac cttatatttc
     1021 aactgctaaa cctcaattta tcacaaatat cgctcactgc aaaatttcta tatttttatt
     1081 atatcatagc atataattaa tattttcaat taatttttac atttaattat gtttaaattc
     1141 tataataatg caactttaat gtttcttcct ggaactaata taaaaactat ttcagaaaga
     1201 ttaggtcatg cagatataaa aataactatg aatagctact ctcagttttt agaagagatg
     1261 gacagagaag catttgaaaa tttgagcaaa atactattta ttgtatttta aagaagatga
     1321 cttattcaat atttgatgct agaatataat taataaaaat ttaattatag gtgattgtat
     1381 tatgaatatt attaaaagca taactttact cttaacatta ttaattgtga tattaatgac
     1441 aggctgttcc ccaagagaaa gtgctagtga agttgcaaaa aaatatattg ataagatgaa
     1501 ctctggtgac tatgaaacag catatagttt attaagtaaa gatagtaaaa aaaaaattag
     1561 tatagaaaat cttgaagaat ttcaaaatat tttagttagt acaa
//
LOCUS       DAMJVG010000188         1566 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.194, whole genome shotgun sequence.
ACCESSION   DAMJVG010000188 DAMJVG010000000
VERSION     DAMJVG010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1566)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1566)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1566
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.194"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            81..1541
                     /locus_tag="PC512_003768"
     CDS             81..1541
                     /locus_tag="PC512_003768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp28"
                     /protein_id="HDF2443438.1"
                     /translation="MKFYKRILTLTLSISFVFANIQLVDAISSVEKIQGKNKYEIAGK
                     IADKNAYKTAYKTAYKTAILINTSNSIADGLSASGLAGALNAPILLTEKNTIPTETSA
                     RLKNVSKVYIIGGTYSISTSVENSLKSKKMKVVRIKGNDRIKTSYNVAKEINSIKKVN
                     TVMLTNAYKGEADAISIASVAARDKAPIILTNGQSIPFSTSGLKSYVIGGTASMSTTL
                     VNNTKSTRLGGSTRFETNKAIINKFYKDAREFYIAGAYELTNALVGSSLSKHGPMVLV
                     NDGSNKSILKNAKKITSIGYIDSNIVQQCLNITNGIGDINTGVVKNVKPTTKTIKDGM
                     YKVGKDISAGEYLITSNSGSYASYYEVTSDSTGNADSILSNDIFSGTRYITLKNGQYI
                     KIEDSTMTLAKYAKAQKAKNGKFGNGMYKIGLEIPAGEYIIMSNSSDAYYEVRNDSLG
                     NAEGIVTNDTFSGRRYITVEEDQYLILNDCYLIENE"
BASE COUNT          646 a          166 c          268 g          486 t
ORIGIN      
        1 ataagtttgt taagtacata actaatttaa gaatatgtat ttatatatta aaaatttatt
       61 atgaggggga caattttatt atgaaattct ataaaagaat attaacattg actttaagta
      121 tttcttttgt atttgcaaat attcaattag tagatgcaat atcatctgta gaaaaaatac
      181 aaggaaaaaa taagtatgaa atagcaggta aaatagcaga taaaaatgca tataaaactg
      241 catataaaac tgcatataaa actgctatat taattaatac tagtaactct attgcagatg
      301 gattaagtgc aagtggacta gcaggagctt taaatgcccc tatactatta actgaaaaaa
      361 atactatacc aactgagaca tctgcaagat taaaaaatgt atcaaaagtt tatataattg
      421 gaggaacata ttctattagt acatctgtcg aaaattcatt aaaatctaag aaaatgaaag
      481 ttgtaagaat taagggaaat gacagaataa aaacaagtta taatgttgca aaagaaataa
      541 attcaataaa aaaagtcaat actgttatgc taaccaatgc atataaagga gaagcagatg
      601 ctataagtat tgcatctgta gcagcaagag ataaagcacc aataattctt actaatggac
      661 aaagtatacc tttttcaact agtggtttaa agtcttatgt aataggagga acagcttcaa
      721 tgagtaccac tttagtaaac aatactaaat ctactagact aggggggagt actcgttttg
      781 aaactaataa agcaataata aataagtttt ataaggatgc tagagagttt tatatagctg
      841 gagcttatga attaacaaat gcacttgtag gatcttcttt atcaaaacat ggtccaatgg
      901 ttttagttaa cgatggtagc aataaaagca ttttaaaaaa tgctaagaag ataacttcta
      961 taggatatat agattcaaat atagtacaac agtgtttaaa tataacaaat ggaattggag
     1021 atattaatac tggggttgta aaaaatgtta aacctactac aaagactata aaagatggaa
     1081 tgtataaggt tggaaaagat atctcagcag gtgaatactt aataacttca aactcaggaa
     1141 gttatgcttc ttattatgaa gttacaagtg atagtacagg taatgctgat agtatacttt
     1201 caaatgatat ttttagtggg actagatata tcaccttaaa gaatggtcaa tatattaaaa
     1261 ttgaggattc aacaatgaca ttagcaaagt atgctaaagc ccagaaggcc aagaatggta
     1321 agtttggaaa tggtatgtat aaaattggat tagaaattcc tgctggagaa tatattataa
     1381 tgtcaaattc ttctgatgca tattatgaag ttagaaatga tagcttaggt aatgcagagg
     1441 gaatagttac taatgatact ttttcaggaa gaagatatat aacggttgag gaagatcaat
     1501 atttaatatt aaatgattgt tatttaattg aaaatgaata gatgtaattg tatttaatag
     1561 taaatc
//
LOCUS       DAMJVG010000189         1404 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.195, whole genome shotgun sequence.
ACCESSION   DAMJVG010000189 DAMJVG010000000
VERSION     DAMJVG010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1404)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1404)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1404
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.195"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(592..1347)
                     /locus_tag="PC512_003769"
     CDS             complement(592..1347)
                     /locus_tag="PC512_003769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1835 domain-containing protein"
                     /protein_id="HDF2443439.1"
                     /translation="MAHICFEDICYLLLKEAMKLKLIPHNKIVLFEDDLSIGNIFDVN
                     NYELRENIFKIRNVFENNPKLLFKPDLLEDRKLSKCRNIIIWCANNPKDLCGVYYVVS
                     KFQDKNIKIALVDEKKTEDALIRYSFTSEMSPEDFPFFLDKTLEIGFNEKLEFKNKWD
                     VLVKENSIFRALVGNEIKSVEETYFDKYILRNISDKWQPLIEVVANCMFEDEMRVKDW
                     FILWRLEKMASLKIVKIKGSKGDFYSDKEIRKV"
BASE COUNT          498 a          211 c          103 g          592 t
ORIGIN      
        1 aattaataaa agagtatatt ttaaatctaa aagctatagg ttgaaacata ctctttttat
       61 tttgtttatt tatagcttta gttattaatc atatataaat ctacaaaacg tattcctagt
      121 aacttatatt ttttgatatc tacaatcata agactatatt attggattca tacctcaaaa
      181 atattgcctt ctgaacatta ttatattcaa agctatgtta atttacaatg atatatccta
      241 acatgtattg attaaaaaaa attaaaactt gcttttcatc tcctatatct aaagaagtgg
      301 tatttagaat aaactattgt aatattaaag ttgaaatttt ctagtttatt tactctatag
      361 caccatattt taatactatt aagtaaaaat gtagttaaaa tatatactaa tatccctgaa
      421 ataagtattt cttttttatt tagcacactt attcgtaagg tattagttat tatatttcca
      481 aattatagaa taaatattat acttattgct aattataata ttaatactgt taagatattt
      541 ttcttcatag ttatacccat tatttaatac aatttattat aaattcaatt tttaaacttt
      601 tcttatctcc ttatcagaat aaaaatcccc tttacttcct tttattttta ctatttttaa
      661 acttgccatc ttctctaatc tccaaagtat aaaccaatct tttacacgca tttcatcttc
      721 aaacatacag tttgcaacca cttcaattaa aggttgccat ttgtcactga tatttcttaa
      781 tatatattta tcaaaataag tttcttcaac acttttaatt tcgttaccta ctaatgctct
      841 aaaaatagaa ttttctttaa ctaacacatc ccatttattt ttaaattcta gtttttcatt
      901 aaagccaatt tctagtgtct tatctaaaaa gaatggaaaa tcttctggag acatttcact
      961 ggtaaatgaa tatctaatta gagcatcttc tgtctttttt tcatctacta atgcaatctt
     1021 tatattttta tcttgaaact tactcactac ataatatact ccacacaaat cttttgggtt
     1081 atttgcacac catattatta tatttctaca ttttgataat ttcctatctt ctaacaaatc
     1141 tggcttgaat aatagtttcg gattattttc aaaaacattt ctaatcttaa aaatattttc
     1201 tcttaattcg tagttattta catcaaaaat attacctatt gataaatcat cttcaaataa
     1261 tacaatttta ttatgtggta ttaactttaa cttcattgct tcttttaata acaaataaca
     1321 aatatcctca aagcatatat gtgccataaa attcacctct tttaaaatta acaatttatt
     1381 ttattataat atataaactg taat
//
LOCUS       DAMJVG010000190         1357 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.196, whole genome shotgun sequence.
ACCESSION   DAMJVG010000190 DAMJVG010000000
VERSION     DAMJVG010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1357)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1357)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1357
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.196"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            493..1173
                     /locus_tag="PC512_003770"
     CDS             493..1173
                     /locus_tag="PC512_003770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2443440.1"
                     /translation="MQIDVLIIDGDKNSSQELKNFLEGKGINVYLAYNCKDAIIKIFS
                     KKFDLIFLEIILVDGDGWDFCKKVRSITTCPIIHITYINENQSILNALNSGGDDYLIK
                     PLNLEILYAKVKAILRRRDLFLNNNKNNIKLEDYNRASGVIKLENKMIKLTPTENRLL
                     NYFIENAEKTLTIKEIYEHVWMNEYLDDNYSVVVAVSGLRKKIEKDYKNPQKIITIRE
                     VGYYFNKI"
BASE COUNT          598 a           85 c          201 g          473 t
ORIGIN      
        1 aataatatta taaaaataaa agtgatatat tgtgtaataa tcgaaatttt atactttggt
       61 taaaataatt ttatatatag tgcctaatgt ataacctaat gctcgtagac aataatgtgg
      121 atattatcaa atttattttt ataatagaaa ttttaattta tatctatatt aaattgttaa
      181 agatataatt atgagaataa aaaatatagc cttgaattat ataattgtat atgcttatct
      241 ttatacagta aataaaaaat caaatgaaat accaaataaa gtgtatatct taaaacaatt
      301 tactagagat acaaggatgc tatgtgaatt ttgaagtgtg cagtttagat aataaatata
      361 tataaataat aaagaaaatg gatttatagt atttaaaatt tcttataagg gtaaaaaatg
      421 ctattagaaa atgtactaaa aatatttttc caattcttta tagaaaaata atgatattta
      481 ggagagattg taatgcaaat tgatgtattg ataattgatg gagataagaa tagttctcaa
      541 gagctgaaaa attttttaga aggaaagggg ataaatgtct atttagcata taattgtaaa
      601 gatgctatta taaaaatatt tagcaagaaa tttgacttaa tatttttaga gataatttta
      661 gttgatggtg atggttggga tttttgtaaa aaagttagaa gtataactac ttgcccaatt
      721 attcatataa cttatataaa tgaaaatcaa agtattttaa atgctttaaa ttctggagga
      781 gatgattatt taataaagcc tttaaattta gaaatattat atgcgaaagt gaaagctatt
      841 ttaagaagaa gagatttatt tttaaataat aataaaaata atataaaact agaagattat
      901 aatagagcta gtggagtaat aaagttagaa aataaaatga taaagttaac tccaacagaa
      961 aatagattat taaattactt tatagagaat gctgaaaaga ctctaactat taaggagata
     1021 tatgaacatg tatggatgaa tgagtattta gatgataatt atagtgtagt ggttgctgtg
     1081 agtggattaa gaaagaaaat agagaaagat tataaaaatc ctcaaaaaat tataacgata
     1141 agagaagtag ggtattactt taacaagata taaagcttta taaacagaat gaatgataag
     1201 gcatagataa tatgttagta tattacaaga gtttttgttc taacgatata tttgtaaaat
     1261 tagatttaat ttacttaatt aaattatagc agtagaataa atataaaaaa tgtctgaaat
     1321 attatagaca tcagtaaaat atataaaact ataatat
//
LOCUS       DAMJVG010000191         1337 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.197, whole genome shotgun sequence.
ACCESSION   DAMJVG010000191 DAMJVG010000000
VERSION     DAMJVG010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1337)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1337)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1337
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.197"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            27..101
                     /locus_tag="PC512_003771"
     tRNA            27..101
                     /locus_tag="PC512_003771"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:59..61,aa:Thr,seq:tgt)
     gene            116..200
                     /locus_tag="PC512_003772"
     tRNA            116..200
                     /locus_tag="PC512_003772"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:150..152,aa:Tyr,seq:gta)
     gene            210..293
                     /locus_tag="PC512_003773"
     tRNA            210..293
                     /locus_tag="PC512_003773"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:244..246,aa:Leu,seq:tag)
     gene            323..399
                     /locus_tag="PC512_003774"
     tRNA            323..399
                     /locus_tag="PC512_003774"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:357..359,aa:Arg,seq:tct)
     gene            407..482
                     /locus_tag="PC512_003775"
     tRNA            407..482
                     /locus_tag="PC512_003775"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:440..442,aa:Gln,seq:ttg)
     gene            571..659
                     /locus_tag="PC512_003776"
     tRNA            571..659
                     /locus_tag="PC512_003776"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:605..607,aa:Ser,seq:tga)
     gene            663..738
                     /locus_tag="PC512_003777"
     tRNA            663..738
                     /locus_tag="PC512_003777"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:696..698,aa:Phe,seq:gaa)
     gene            745..818
                     /locus_tag="PC512_003778"
     tRNA            745..818
                     /locus_tag="PC512_003778"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:779..781,aa:Met,seq:cat)
     gene            833..909
                     /locus_tag="PC512_003779"
     tRNA            833..909
                     /locus_tag="PC512_003779"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:867..869,aa:Ile,seq:cat)
     gene            933..1009
                     /locus_tag="PC512_003780"
     tRNA            933..1009
                     /locus_tag="PC512_003780"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:967..969,aa:Pro,seq:tgg)
     gene            1017..1093
                     /locus_tag="PC512_003781"
     tRNA            1017..1093
                     /locus_tag="PC512_003781"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1051..1053,aa:His,seq:gtg)
     gene            1102..1177
                     /locus_tag="PC512_003782"
     tRNA            1102..1177
                     /locus_tag="PC512_003782"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1135..1137,aa:Lys,seq:ttt)
     gene            1185..1258
                     /locus_tag="PC512_003783"
     tRNA            1185..1258
                     /locus_tag="PC512_003783"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1217..1219,aa:Cys,seq:gca)
     gene            1265..1336
                     /locus_tag="PC512_003784"
     tRNA            1265..1336
                     /locus_tag="PC512_003784"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1297..1299,aa:Asn,seq:gtt)
BASE COUNT          320 a          309 c          355 g          353 t
ORIGIN      
        1 ccccttccag gtcgccaaaa taaaatgctg gtgtggctca acggtagagc agctgacttg
       61 taatcagcag gttgtaggtt cgattcctat caccagctcc atgtaaaatt aatacggagg
      121 atttcccgag cggccaaagg gggcagactg taaatctgtt gtcatcgact tcggtggttc
      181 gaatccacca tcctccacca aaaaaatgcg cggatgtggc ggaattggca gacgcactag
      241 acttaggatc tagcgccatt ggcgtggggg ttcgactccc ttcatccgca ccatttttgt
      301 ttgatataca tatatatatt gtgggtgcat agctcagctg gatagagcaa cgcccttcta
      361 aggcgtgtgt ccggggttcg aatccctgtg cgctcaccac atatattggg gattagccaa
      421 gtcggtaagg cacatgactt tgactcatgt atgcgtaggt tcgagtcctg catccccagc
      481 caaatgatgt attactaagc tatatttgaa ttatttttat tttaaatata gttaggttca
      541 attttagaat aagtttaagt atccgaatgt ggagaggtgt ccgagtggtt taaggagctg
      601 gtcttgaaaa ccagtgactt cgaaaggggc cgtgggttcg aatcccaccc tctccgccaa
      661 atgcccagat agctcagtcg gtagagcagg ggactgaaaa tccccgtgtc ggtggttcga
      721 ttccgcctct gggcaccaaa atatggcggt atagcttagt tggctagagc gttcggttca
      781 tacccgaaag gtcataggtt cgactcctat taccgctact aaaatttaat gtgggccatt
      841 agctcagttg gttagagcgc ccggctcata accggtaggt ctggggttcg agtccctgat
      901 ggcccaccac attaaattaa ttaatataaa ttcgaggtgt agcgcagttt ggtagcgcac
      961 atggtttggg accatggggc cgggggttcg agtcccttca cctcgaccaa tataaggtgg
     1021 gtatagctca gttggttaga gcgccagatt gtggctctgg aggtcgtgag ttcgactctc
     1081 attatccacc ccaattcata tggtctatta gctcagtcgg tagagcacct gacttttaat
     1141 cagggtgtcc cgcgttcgag tcgcggatag atcaccaaaa aggtggcgac atagccaagt
     1201 ggtaaggcag tggactgcaa ctccttgatc cccagttcga atctgggtgt cgcctccaaa
     1261 atattccaag gtagctcaac ggtggagcaa ccggctgtta accggtaggc tgtgggttcg
     1321 agccccaccc ttggagc
//
LOCUS       DAMJVG010000192         1305 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.198, whole genome shotgun sequence.
ACCESSION   DAMJVG010000192 DAMJVG010000000
VERSION     DAMJVG010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1305)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1305)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1305
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.198"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            61..792
                     /locus_tag="PC512_003785"
     CDS             61..792
                     /locus_tag="PC512_003785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443441.1"
                     /translation="MLSKKNVSLIILVIILSLLTAIFIFNNKNTNNKLKEVTKNNEEI
                     VPKNLEGLSIEQLIEIRDKAIDKNLEGLREFGEDSVKKRKDSILNFEFGLVAFVNKNY
                     SNLTEKEKLIRQINIVNYENSINDIMDPSGSFFELANQNYQVNEFLLKNGKDYKEWSY
                     EGLDFLIDHLEELCKFVDFDVKDVIDIIDPTIKTDLSEEQKKSLNDKLKKISSSDTLS
                     EEVKKEIKNWENNLNNLNMNKNNSN"
     gene            complement(949..1155)
                     /locus_tag="PC512_003786"
     CDS             complement(949..1155)
                     /locus_tag="PC512_003786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443442.1"
                     /translation="MSKYSSLWEYFKKNNSQSFKLTFEEIKDIAGIEIDHSFLKYKKE
                     LNEYGYQVGKISLKEKTVIFDKIG"
BASE COUNT          541 a          138 c          153 g          473 t
ORIGIN      
        1 tcttcataaa caaatttatt tttcacaagt acaatactta tttaaaaaag gaggtttaat
       61 atgttaagta aaaaaaatgt aagtttaatt attttagtaa taattttaag tttattaact
      121 gctatattta ttttcaataa taaaaatact aacaataaat tgaaagaagt tactaagaat
      181 aatgaagaaa tagtacctaa aaacttagaa ggtttaagta tagaacaatt aatagagatt
      241 agagataaag ccattgataa aaatttagaa ggtcttaggg aatttggaga agattcagta
      301 aaaaaacgta aagattcaat tttaaacttt gaatttggat tagtagcttt tgttaacaag
      361 aattatagca acttaacaga aaaagagaaa ttaataagac aaattaatat tgttaactat
      421 gaaaactcta taaatgatat aatggatcct tcaggttcat tctttgaatt agcaaatcag
      481 aattaccaag tgaatgagtt tctattaaaa aacggaaaag attataaaga atggtcatat
      541 gaaggtctag attttctaat tgatcatcta gaagaactgt gcaaatttgt tgattttgat
      601 gtaaaagatg taatagatat tattgatcct acaataaaaa cagacctttc agaggaacaa
      661 aagaaatctt tgaatgataa attaaagaaa atatcttcaa gtgatacttt aagtgaagaa
      721 gttaaaaagg agataaaaaa ctgggaaaac aatttaaata atttaaatat gaataaaaat
      781 aattctaatt aattttctca taagaaaaat gcttatatcg tgataatgtg aaatgtacat
      841 aattataaac aaaaaagggg ctgtgacact aaaaaatagt gctacgccct tttttatttg
      901 taataatcat caatacaaat tattttatta tatgtaatta tttatgtctt aaccaatttt
      961 atcgaaaata acagtcttct cttttaaaga gatttttcct acttgatatc catattcatt
     1021 taattccttt ttatatttca aaaacgaatg gtctatctct atcccagcaa tatcttttat
     1081 ttcttcaaaa gttaatttaa acgattgact attgtttttc ttaaaatatt cccataaaga
     1141 actatattta ctcatcttat atcactcctt ttaaaatcat atcttatcta ttaatttata
     1201 ttctatcatt attaatgtat aaagtcatgc tacttattat ttatatataa aaatatccaa
     1261 ataataagta gcaatttttt atagtcataa tatttttttc agatt
//
LOCUS       DAMJVG010000193         1301 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.199, whole genome shotgun sequence.
ACCESSION   DAMJVG010000193 DAMJVG010000000
VERSION     DAMJVG010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1301)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1301)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1301
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.199"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            <1..>1301
                     /locus_tag="PC512_003787"
     rRNA            <1..>1301
                     /locus_tag="PC512_003787"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          349 a          280 c          391 g          281 t
ORIGIN      
        1 agctgaggcc gaaaggcgta ggtgatggac aacaggttga tattcctgta ctaccgataa
       61 ccgtttgaga gaagggatga cacagtagga taagctaagc acactgttgg ttatgtgtgc
      121 ccaagcattg aggcagtcaa agtaggcaaa tccgctttga taatgctggg atgtgatggg
      181 gagcgaaatt tagtagcgaa gtagctgatt tcacactgtc aagaaaagtc tctatcgagg
      241 ttaaaggtac ccgtaccgca aaccgacaca ggtgggtgag gagagtatcc taaggccagc
      301 gagagaactg ttgttaagga actcggcaaa atgaccccgt aacttaggga taaggggtgc
      361 caccatcagg tggccgcaga gaataggccc aagcgactgt ttaccaaaaa cataggtttc
      421 tgctaagtcg caagacgatg tataggagct gacgcctgcc cggtgctgga aggttaaggg
      481 gatctgttag agcaatcgaa gcagtgaact taagccccag taaacggcgg ccgtaactat
      541 aacggtccta aggtagcgaa attccttgtc gggtaagttc cgacccgcac gaaaggcgta
      601 acgatttggg cactgtctca acaacagact cggtgaaatt gtaattccgg tgaagatgcc
      661 ggatacctgc gacaggacgg aaagacccca tggagcttta ctgtagcttg acattgggtc
      721 ttggtactac atgtacagga taggtgggag gctttgaaac caggacgcca gttttggcgg
      781 agccatcctt gggataccac ccttgtagta ctgggactct aaccataggc catgaatctg
      841 gtcttgggac actgtcaggt gggcagtttg actggggcgg tcgcctccca aaaggtaacg
      901 gaggcgctca aaggttctct cagtacggtc ggaaatcgta cgtagagtgt aaaggcaaaa
      961 gagagcttga ttgcaagaca tacaggtcga gcaaggatga aaatcggact tagtgatccg
     1021 gtggttctgc gtggaagggc catcgctcaa cggataaaag ctaccctggg gataacaggc
     1081 ttatctcccc caagagtcca catcgacggg gaggtttggc acctcgatgt cggctcatca
     1141 catcctgggg ctgtagtagg tcccaagggt tgggctgttc gcccattaaa gtggtacgcg
     1201 agctgggttc agaacgtcgt gagacagttc ggtccctatc cgtcgcaggc gtaggaaatt
     1261 tgagaagacc tgtccttagt acgagaggac cgggatggac g
//
LOCUS       DAMJVG010000194         1172 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.200, whole genome shotgun sequence.
ACCESSION   DAMJVG010000194 DAMJVG010000000
VERSION     DAMJVG010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1172)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1172)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1172
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.200"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            4..864
                     /locus_tag="PC512_003788"
     CDS             4..864
                     /locus_tag="PC512_003788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDF2443443.1"
                     /translation="MLLKKDRITFSEILILIVGCILMAISLNLFFNPHAIAAGGITGL
                     GVVLNSLFGVELWIVNLLLNVPLFIFAYKILSKKDCFKTVLGIIFLTIALKLTANMAT
                     LDITNDMYLAIISGSILMGVGQGLIFRINGSTGGTDLMALLLNKYFPTFSIPVLMGIV
                     DCVVVVLSGIVNRQVEIALYSTVALYILVKVSDLLIEGFNYSKSFTIISDLSKDISKK
                     IMEDLDRGATILKGEGAYTGENKNVLLVVVEKKEVVELKKLVKNVDPNAFIIITDIHE
                     ALGNGFKKIE"
BASE COUNT          428 a          129 c          166 g          449 t
ORIGIN      
        1 gtgatgttat tgaaaaaaga tagaataact ttttcagaaa ttttaatatt aattgtaggc
       61 tgtatattaa tggccatttc tcttaactta ttttttaatc cacatgcaat cgctgctggt
      121 ggtataacag gacttggagt tgttttaaat tcattattcg gtgtagaact ttggattgtc
      181 aatttacttt taaatgttcc attattcata tttgcttaca aaatactttc aaaaaaagat
      241 tgttttaaaa cggttttagg aataattttt cttaccatag cacttaagct tactgcaaat
      301 atggctacat tagatataac aaatgatatg tatcttgcaa ttatatctgg ttctatttta
      361 atgggagttg gtcaaggact tatttttaga ataaatggct ctacaggtgg aactgattta
      421 atggcactcc tactaaataa atattttcct acatttagta tacctgtttt aatgggtatt
      481 gtagactgcg ttgtagttgt tttatcaggt atagtaaata gacaggttga aattgcactt
      541 tattcaactg tggctttata cattttagta aaagttagtg acttgcttat tgaaggattt
      601 aattattcca aatcattcac tattatatct gacctttcaa aagatataag taaaaaaata
      661 atggaagatt tagatagagg tgcaactatt ctaaaaggag aaggtgcata tactggagaa
      721 aataaaaatg tacttttagt agtagttgaa aagaaagaag ttgtcgaatt gaaaaaatta
      781 gtaaaaaatg tcgaccctaa tgcttttatt ataattacag atatacatga agctttaggt
      841 aatggattta aaaaaataga ataactaaca aataaatagc aagtataatt aacatataca
      901 aattcaactt tttatatgtt atattatact tgctatttat atattatact tgctatttat
      961 atattataat tgttgttttt aagataaaaa ttaaatgtat caattattgt tttatacaag
     1021 tatttccaaa tccgttctca tttagatagt atgcttagaa attttagaat tattgagtct
     1081 aactttatta cttactttac tttataacaa tcaaatacaa atttaaatat tataaaacta
     1141 caaaataatt taaagcatat aatgtcaata tg
//
LOCUS       DAMJVG010000195         1167 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.201, whole genome shotgun sequence.
ACCESSION   DAMJVG010000195 DAMJVG010000000
VERSION     DAMJVG010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1167)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1167)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1167
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.201"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(19..195)
                     /locus_tag="PC512_003789"
     CDS             complement(19..195)
                     /locus_tag="PC512_003789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443444.1"
                     /translation="MFGNKMDKCTHVLTAYISSSYDYCNFLDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     regulatory      complement(250..347)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            573..956
                     /locus_tag="PC512_003790"
                     /pseudo
     CDS             573..956
                     /locus_tag="PC512_003790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431032.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
BASE COUNT          497 a          139 c          156 g          375 t
ORIGIN      
        1 ctagaaatca atgtctatct aattatactt acttaccaat accattactt ggtgtaaaca
       61 agactctact acattttctc cgtactctaa tataaaatca tctaactgtg tatctaaaaa
      121 attacaataa tcatacgaac tgctaatata agcagtcaat acatgtgtac atttatccat
      181 tttatttcca aacatataaa ttattatccc cctaaaaaac tttcataaaa acaaaaagaa
      241 cactatctct ttggcaactg gctgacataa ctcataagat atttatataa gtcttagtcc
      301 ctatagcttt gcgtcactaa atttctctag ttttgccgat ttagttttat tctacaacta
      361 aaataataca atagaattag ttattattca acaggattgt ttgaaagtta aataaattta
      421 tagatatgaa cattatttta cacttaaaaa cagactaaac acgtagagta cctggtaaaa
      481 attaaatata gtttttgttc taaaaagctc ctattataat ttaagctaga taaatttgaa
      541 gaagtgacat aaattgaaag aaggaatata ttatgctaaa taaaaaatta ccagatacag
      601 aattaaaaat tatgaaatgc atatggcata ctggttataa aactgtaata tcaaaagatg
      661 ttgcagatga aatagaaaaa acatatggtt ggaagcatac aactacaatt atacttttag
      721 ctagattaac caaaaaaggt tttttaatat catagagaat tgggaggcat gtacactata
      781 cagtattaat aaaagagaga gaatatctca aaatagaggg aaaaagagtt tttagaggtt
      841 tacataacaa tcctttatca gaattaattt caaaattaca tgatggagaa gaaataactg
      901 aagaaaaaat aatagaaata ggaagttgga taaaaagctg gaaatataaa gattaataaa
      961 taaaaggtag ctaataatat aagtgctacc ttttttatgt ggataatatt ggtgataagt
     1021 tgtggaaaac ttatataaaa attgtggata aagtgttttg ctgacatttt actgacaaaa
     1081 gttaaaaaaa taaatgttat atattgtaaa atgttgaaaa atagccatat atataaaata
     1141 taagtaacac tatagataaa ttactgt
//
LOCUS       DAMJVG010000196         1160 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.202, whole genome shotgun sequence.
ACCESSION   DAMJVG010000196 DAMJVG010000000
VERSION     DAMJVG010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1160)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1160)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1160
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.202"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(287..778)
                     /locus_tag="PC512_003791"
     CDS             complement(287..778)
                     /locus_tag="PC512_003791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbM family protein"
                     /protein_id="HDF2443445.1"
                     /translation="MGMIGCYTKISEENVFKLQQAEENLQDFVFEDANENSTINIDKA
                     WHAIHFTLTGCPFGGDDDNIFSKLVLSGNILMEIDGEFPVMLITANDVKKLSKAMNSL
                     EEQAFRKRFNINEMLENNIYPVMNDESEDDFFEYVWANLIELKKFIQEASNDGLAVIF
                     FIM"
BASE COUNT          448 a          164 c          108 g          440 t
ORIGIN      
        1 aaaaatgtga taagtatcca aaagaattac tggatataat aggatagggt atttagcctt
       61 ttaagataaa taaaaatatc tgcaactata tattgcaaaa atttaaaact aatttatata
      121 tgctaatata aatatttata aagacataag acaaatttac ctacagattt aaatttaact
      181 tatatatttt aaaaggctaa tataatatgt attttcttct atacaatcaa aaggcttcat
      241 atctaagata tgtgatgaca ctaatattca caatttttag taattatcac attataaaaa
      301 atattacagc tagtccatca ttagatgctt cttgtataaa ctttttaagc tcaattagat
      361 ttgcccatac atattcaaaa aaatcatctt cactctcatc attcataaca ggataaatat
      421 tattttctaa catctcatta atattaaatc tttttctaaa tgcttgttct tccaaactgt
      481 tcattgcttt tgatagtttt tttacatcat ttgctgtaat caacatgaca ggaaattctc
      541 catcaatttc cataagtatg tttccactta gtactaattt gctaaatata ttatcatcat
      601 ctccaccaaa aggacaacct gtcaaagtaa agtgaatggc atgccatgct ttatcaatat
      661 tgatagtact attttcgttg gcatcttcaa aaacaaaatc ttgtaaattt tcttctgctt
      721 gctgtaattt aaaaacattc tcttcactta ttttagtata acatcctatc attcccataa
      781 ttacattcct cctaagtagc gtttttttaa ttgtaactta taattaaact tagttacaat
      841 aaaatatatt gagaaaagta ttatttcatc ttaaatttaa atacctatat tatcaactaa
      901 aattctgtgt ttatagcgta agtattattt tttcctaaaa attaaatgaa tcagaggttc
      961 tataggcaat attgactata aataagaact attacttttt aaaaaaaatt taagaaatta
     1021 tactgtagaa tcatgctcta cttattagct ttaaataaaa aataaatcat gttctcaaat
     1081 taaataataa ataacaataa atttaaattt taaactataa gagtttctga agtgttaata
     1141 agcataccaa taattatatg
//
LOCUS       DAMJVG010000197         1125 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.203, whole genome shotgun sequence.
ACCESSION   DAMJVG010000197 DAMJVG010000000
VERSION     DAMJVG010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1125)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1125)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1125
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.203"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(205..1074)
                     /locus_tag="PC512_003792"
     CDS             complement(205..1074)
                     /locus_tag="PC512_003792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HDF2443446.1"
                     /translation="MVIIKAIELYKKLDLEFNIKNINDDWSFMNFENDFITPEFRKKY
                     IGLVLDNAQNINKVYTTTFPDKEIIKQVIDKDEKDILIFSHHAMGYIASDEGFPFHDI
                     PLSYMEEMKNRRISFYVLHSPLDNYSDYSTSVSFAKAMGLEIVKPFCKYDDKIEVGVI
                     CKTSLKSIEEIKELIKKSVGHDVKLYDYGDSVLKDGLVAIAAGGGSYPFVAREVAELG
                     INLYITGFTKPLKHFEPVLEFHQIAKDNLINVIGATHYSTEKFACMGMVDYFKNLGLE
                     SEFLQGKYYLEDL"
BASE COUNT          421 a          174 c          108 g          422 t
ORIGIN      
        1 tacatcaaaa aataaactaa aaaatatcga aaaataattt aaaagacatc aaaactaaat
       61 cttctaatca gcaattaaaa gtctattttc ttagtttaaa aaataaagat agattttttc
      121 aaaacactgg ataaataggt aaaaaaataa acagttagta aaataaattt ttactaactg
      181 tttattttta ttgtttaata tgtcctataa atcctctaag taatactttc cttgcaaaaa
      241 ttctgattct aaacctagat ttttaaaata atcgaccatg cccatacacg caaatttttc
      301 tgtagaataa tgagtagcac ctataacatt aattaaatta tcttttgcta tttgatggaa
      361 ctctaatact ggttcaaaat gttttaaagg cttagtaaac ccagtaatat atagatttat
      421 accaagttca gcaacttctc ttgctacaaa tggataactt cctccccctg ctgcaatagc
      481 aactaaacca tcttttaata cagaatctcc ataatcatac aatttcacat catgaccaac
      541 agatttttta attaattcct taatctcttc tattgatttt agtgatgttt tacatataac
      601 tcctacttca attttatcgt catatttaca aaatggtttg actatttcta aacccatagc
      661 ttttgcaaaa ctaacagaag ttgaatagtc actatagttg tctagtggag aatgtaatac
      721 ataaaaagaa attctacgat ttttcatctc ttccatataa gatagtggta tgtcgtgaaa
      781 tggaaaacct tcatctgatg ctatgtatcc cattgcatga tgtgaaaaaa ttaaaatatc
      841 tttttcatct ttatctataa cttgcttaat tatttcttta tcaggaaaag tagttgtgta
      901 tactttatta atattttgag cattatctaa tactaatcct atgtattttt ttctaaattc
      961 tggagtaata aaatcatttt caaaattcat aaaactccaa tcatcattaa tatttttaat
     1021 attaaattct aaatctaatt ttttataaag ttcaattgcc ttaataataa ccactccttt
     1081 ataataatat tgaattacta catattaata tagaaatttc cgata
//
LOCUS       DAMJVG010000198         1124 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.204, whole genome shotgun sequence.
ACCESSION   DAMJVG010000198 DAMJVG010000000
VERSION     DAMJVG010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1124)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1124)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1124
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.204"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(312..818)
                     /locus_tag="PC512_003793"
     CDS             complement(312..818)
                     /locus_tag="PC512_003793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HDF2443447.1"
                     /translation="MGFREVKIEELQFNPFTKIGKEWLLITAGDSEKFNTMTASWGGV
                     GVYWGKNVVTTYIRPQRYTKEFVDSNDTFTIAFFDETYREALNICGTISGRDINKIEK
                     AGLTPYFVDDTVAFEEANMIIVCKKLYHGNMPPENFDAKENDKKWYPEKDYHTMYISE
                     IIKVLVKE"
BASE COUNT          406 a          161 c          102 g          455 t
ORIGIN      
        1 actttgaaat tatttacatt aaaataaatc aagtacaaat gccataaatt aagtgtttct
       61 agttagcata aaaatactta taaagtatac tcaaatattt caaataaata cttttattca
      121 aataaatctc tacttatata agtgcttata taaataaaaa gatgaactat agtaaatata
      181 gttcatcttt tttataatag tatttattta aaattaatat ttatttagtt agtagcatct
      241 acttagatat cagataagaa agcacagtca tttacttata ataagttctt ttcatatatt
      301 ttttattata attattcttt tacaagaact tttataattt ctgaaatgta catagtatga
      361 tagtctttct ctggatacca ttttttatca ttttctttag catcaaagtt ttctggtggc
      421 atattaccat gatatagctt tttacatact ataatcatat tagcttcttc aaaagctacc
      481 gtatcatcca caaaatatgg tgtaagtcct gctttttcta ttttatttat atctctacca
      541 gaaatagtgc cacaaatatt taaagcttct ctatacgttt catcaaagaa ggcaattgta
      601 aatgtatcat tactatctac aaattctttt gtatatctct gtggtcttat gtaagttgta
      661 acaacatttt taccccaata gactccaaca ccaccccagc tagcagtcat tgtgttaaac
      721 ttttctgaat caccagctgt tataagtaac cattctttgc caatcttagt aaatggatta
      781 aactgtaatt cctcaatttt tacttctcta aaacccatga cttcatccta cccttcattt
      841 tttaattata taaattaatt gttaaaaatt tgaatatatg tactcttata atactgactt
      901 ttgattgtcc tacataattc atgtaaatta taatacaaca aatcaattac tttcgcaata
      961 agtagttttc atattttata agtgtaaaat atagataaaa tatattgatt ataaagtata
     1021 taatatattt ttaaacctaa agcaatatac aataaaaaaa tgtagaaagt aagtatctct
     1081 ctacattttt tattgtatat tatttttata ttaatttaat ttta
//
LOCUS       DAMJVG010000199         1086 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.205, whole genome shotgun sequence.
ACCESSION   DAMJVG010000199 DAMJVG010000000
VERSION     DAMJVG010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1086)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1086)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1086
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.205"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            152..904
                     /gene="cwlD"
                     /locus_tag="PC512_003794"
     CDS             152..904
                     /gene="cwlD"
                     /locus_tag="PC512_003794"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase CwlD"
                     /protein_id="HDF2443448.1"
                     /translation="MEYYSVFISIHIQGDVVRKYIKHIIFSFAMICLVVVSIFEIKNI
                     SEDVIKYMPVTNKTIILDAGHGGIDPGALNKDKSTSEKDINLAITLKLRELIESSGGL
                     VILTREDDSSLYKEENNKTTRQKYNENLKNRKEIISNSNANMFVSIHLNAFEQSKYYG
                     AQTFYPKDKQDSKELSKCIQEELKRVVDKTNNREVKPRDDIYLLKENNIPSVLIECGF
                     LSNEKECKLLTDETYQEKIAWAIYIGIQKYLS"
BASE COUNT          480 a          110 c          166 g          330 t
ORIGIN      
        1 ctaagtataa tttattgtat agtattgaat gttagataaa catagtgaat taaatagggg
       61 cagaaatata atatcattac ataataatat attaatacca ataaataaag atatatcaat
      121 attaaaaaaa tttaaatgtt tgtactaata tatggaatat tatagtgttt ttataagtat
      181 acatatacag ggtgatgttg tgagaaagta cataaaacat ataattttta gttttgcaat
      241 gatatgtcta gtagtagtat ccatatttga aattaaaaat atttctgaag atgttatcaa
      301 gtatatgcca gtaacaaaca aaactataat tttagatgct ggtcatggag gcattgatcc
      361 aggtgcatta aataaggata agagtacatc tgaaaaggat attaacctag caataacact
      421 taagcttaga gagcttatag aatcaagtgg tggccttgta atattaactc gagaagatga
      481 cagtagcctt tataaagaag aaaataataa aactacaaga caaaaatata atgagaattt
      541 gaaaaataga aaagaaataa tatctaattc taatgccaat atgtttgtct ctatacatct
      601 taatgcattt gaacaatcaa aatactatgg agctcaaact ttttatccta aagacaaaca
      661 agacagtaaa gaattatcga agtgtattca agaagaactt aaaagagtag tagataagac
      721 aaacaacaga gaagtcaaac caagggatga tatatatctt ttgaaagaaa ataatattcc
      781 atcagtactg atagaatgtg gttttttatc aaatgaaaaa gagtgtaaac tcttaactga
      841 tgaaacatat caagaaaaaa tagcatgggc aatctacata ggaatacaaa aatatttaag
      901 ttgaaataac tataaaaata ggtctaaata tgtaaatagc ttgtattaaa gcagttaaaa
      961 tgcattaata taggctattt ttattttgac aaaaaaatat ttaaaataaa agttaaaaag
     1021 ttgttgactt agaataatat agatgatatt atatatgagt gcccaaaagg agcaccaaaa
     1081 taagac
//
LOCUS       DAMJVG010000200         1041 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.206, whole genome shotgun sequence.
ACCESSION   DAMJVG010000200 DAMJVG010000000
VERSION     DAMJVG010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1041)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1041)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1041
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.206"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            411..962
                     /locus_tag="PC512_003795"
     CDS             411..962
                     /locus_tag="PC512_003795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan transporter"
                     /protein_id="HDF2443449.1"
                     /translation="MKTNTKKLTLNAILLAMGLLIHQITPAIGLPMKPDVPLAMLFVI
                     LVLNRDDYKTCLIAGIVTGIFTALTSSFPGGQIPNVIDKTLTANIVFLLMNISYNMPF
                     IKKLAKKTQDTVVVAIIMPIGTLVSGTIFLLAAQAIVGLPGASFTALFLAVVLPAVLI
                     NLVAGIFLFKIVSLSIRRVSYQA"
BASE COUNT          403 a          115 c          183 g          340 t
ORIGIN      
        1 atcctatgac aaggaagagt agttaaattt aggttcagta tagagagctg aggatggtgg
       61 aatcttagca agaaaaaatt tgatgaatgg cccttagagg aataaattga aatcatagtt
      121 ttgagagtag actttatcgt cagtcgcacg ttatagcgaa taaggtatgt aagtacctga
      181 taatgagatg tatgaaaatt gaattttata ttaattttta tataatttag gtggcaacgc
      241 ggataatctc cgtcctatta gtttaggacg gagtttttta ttttactgaa aatttaaaag
      301 atagaaggtg gtgagaaaga tgttatgaat ttcaaaagct aaagatgatg atatagtagg
      361 ttggcaaaaa aataaattga aaattaaaaa aataggagga agtacaaaaa atgaaaacaa
      421 atacaaaaaa attaacttta aatgcaatac ttttagcgat gggattatta atacatcaaa
      481 tcacaccagc tataggatta ccaatgaagc cagatgtacc actagcaatg ttatttgtaa
      541 tattggtttt aaatagagat gattataaaa cttgtttgat agcgggtata gtaacaggaa
      601 tatttacagc acttacatca agttttccgg gaggtcaaat tcctaatgta atagataaaa
      661 ctcttacagc aaatatagta tttttattaa tgaatattag ttataatatg ccttttataa
      721 aaaaattagc taagaaaaca caagatactg tagtagttgc aataataatg ccaataggaa
      781 ctcttgtaag tggaactatc tttttattag cagctcaagc tatagttggt cttccagggg
      841 cttcatttac agctttattc ttagcagtag tattaccagc tgttttaata aatctagttg
      901 caggaatatt tttattcaag attgttagtc tatcaataag aagagttagt tatcaagctt
      961 aaacacgaaa taatatttta ctttataaag cattataata actaaataac ataagaataa
     1021 agtagattat aactatttta t
//
LOCUS       DAMJVG010000201         1002 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.207, whole genome shotgun sequence.
ACCESSION   DAMJVG010000201 DAMJVG010000000
VERSION     DAMJVG010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1002)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1002)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1002
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.207"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            91..>1002
                     /locus_tag="PC512_003796"
     CDS             91..>1002
                     /locus_tag="PC512_003796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF2443450.1"
                     /translation="MIVVEKAYKFRMYPNKKQQELINKTFGCCRFVYNKYLAKRIDVY
                     KKHKETFTYKQCSSDLTNLKKELKWLKEPDKFSLQNALRDLDNAYKKFFKEKAGFPKF
                     KSKKINRFSYKTNFTNGNIMYCGQHIKLPKLGMVKVRDKQVPQGRILNATISKEPSGR
                     YYVSLCCTDVDIGAFENTNNHIGLDLGIKEFCISSCGDFIENPKYLKKSLNKLAKLQR
                     ELSRKTIGSLNRNKARLKVARFQEHIANQRKDFLQKLSTKLIKENDIICIEDLQVKNM
                     IRNRKLSRLISDVSWSEFIRQLEYKANW"
BASE COUNT          432 a          105 c          153 g          312 t
ORIGIN      
        1 gtgattaata aattgttcac cacagcatta tataatatat taaatatgat aaaatcatta
       61 aaaagtgtat caaaaaacaa ttaaagtgag gtgatagtag tggaaaaagc ttataagttt
      121 agaatgtatc caaataaaaa acagcaagag ttaattaaca aaacttttgg atgttgtaga
      181 tttgtgtata ataagtatct tgctaaaaga atagatgttt ataaaaaaca taaagaaact
      241 tttacttata aacagtgtag ttctgatttg accaatttaa aaaaagaatt aaagtggctt
      301 aaagaacctg acaaattttc actacaaaac gccttaagag atttagataa tgcatataaa
      361 aaattcttta aagaaaaagc aggatttcct aaatttaaat caaagaaaat taatagattt
      421 tcatataaaa ctaactttac aaatggaaac attatgtatt gtggtcaaca tataaaacta
      481 cctaaacttg gtatggttaa ggtaagggat aaacaagtac ctcaaggtag aatacttaat
      541 gctactatat ctaaagaacc aagtggtaga tattatgtat cattatgctg tactgatgta
      601 gatattggag catttgaaaa tactaataat catataggtt tagatttagg aattaaagaa
      661 ttttgtatct caagttgtgg agactttata gaaaatccta agtatcttaa gaagtcatta
      721 aacaaacttg ctaaattaca aagagaatta tcgagaaaaa caatcggtag tttaaataga
      781 aataaagcaa gattaaaagt tgcaagattt caagaacata tagctaatca aagaaaggat
      841 tttctacaaa aattatctac taaattaata aaagagaatg atattatttg catagaagat
      901 ttacaagtaa agaatatgat tagaaatcgt aaactatctc gcttaatttc tgatgtgtca
      961 tggtcagagt ttattcgtca attagaatac aaggctaatt gg
//
LOCUS       DAMJVG010000202          962 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.208, whole genome shotgun sequence.
ACCESSION   DAMJVG010000202 DAMJVG010000000
VERSION     DAMJVG010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 962)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 962)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..962
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.208"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            300..767
                     /locus_tag="PC512_003797"
     CDS             300..767
                     /locus_tag="PC512_003797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDF2443451.1"
                     /translation="MKFLNVLIVVEDIEKSKKFYYDVLGLKVICDFGENVVLEGNISL
                     QEKKLWLEFINKSDSEVKFNGNDAELYFEEDYFDTFVERLSTMRDIDYVHLAIEHRWG
                     QRAIRFYDLDGHIIEVGETMSSVCRRFLDSGLSIDEVAKRMDVTVEYIESVLE"
BASE COUNT          357 a           65 c          169 g          371 t
ORIGIN      
        1 tattagtgta tattaatatt ctcttgaaat taaaaaaaca tagatatttc agtaatctaa
       61 aatagtctac aaaaataaca gttttagcaa aattaataag aatacatata gatttaaacc
      121 taaaagtatg aatgtgtctg ttttttacaa gattaaaatt tatattatat gatacaatta
      181 acttaactat ttcaataaga cttataattt ttttctttat actagacctt attgaaacct
      241 ttatagttta attctaatta tatattataa ataaagtatg tgtatattaa ggaggtaata
      301 tgaagttttt aaatgtttta atagtagttg aagatattga gaaatcaaaa aagttttatt
      361 atgatgtttt ggggttaaag gtaatctgtg attttggaga aaatgttgta ttagaaggga
      421 atatatcatt acaagaaaaa aagctttggt tagagtttat taataagagt gacagtgaag
      481 ttaagttcaa tggaaatgat gctgagctgt attttgagga agattatttt gatacttttg
      541 ttgaaagatt gagtacaatg agagatatag attatgttca tctagctata gagcataggt
      601 ggggtcaaag agcaattaga ttttatgatt tagatgggca tattattgag gttggagaaa
      661 ctatgtcatc tgtgtgtaga cgttttttag atagtggtct ttcaatagat gaggtagcta
      721 aaagaatgga tgtaactgtc gaatatattg aatcagtttt agaatagatg gattatatta
      781 aagtaaaact atattttgta tagaagtaag ggctgtaagt aaacttgtat ggaaacaaat
      841 ttacttacag tttttgtttt tgtaagatac agaatataat atttgttata attttatttg
      901 gatttttaaa aagtgcatga ttttccttac atattataat agaatttaat atttattgga
      961 tg
//
LOCUS       DAMJVG010000203          884 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.209, whole genome shotgun sequence.
ACCESSION   DAMJVG010000203 DAMJVG010000000
VERSION     DAMJVG010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 884)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 884)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..884
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.209"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            1..346
                     /locus_tag="PC512_003798"
                     /pseudo
     CDS             1..346
                     /locus_tag="PC512_003798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889008.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
     gene            656..>884
                     /locus_tag="PC512_003799"
     CDS             656..>884
                     /locus_tag="PC512_003799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443452.1"
                     /translation="MNFRNIYLILMGLGIIILTTIISLIEIKIGFCNEKYFNKLESKY
                     GNIDRKRTIKLEVLYRYVTGFEYIAIGLFTKR"
BASE COUNT          333 a           88 c          128 g          335 t
ORIGIN      
        1 taagctaatt aaaaacctta agaagaacga tattgacact acttgaatta tattatagaa
       61 aagctgaaat aaataaaata gtttgggcta gaataggttt taatttatat ctttctaaag
      121 gagttgcatt aactttaact gatgctggta tagggatttc aggacttttg gctggtgcta
      181 ttcctggtat aggacagtac ttgccactta tagttagatt aattacaatg taccttgagt
      241 caaatataac atctggaaaa atctttaaat ttaaaaaata cgttataata aaggaggtgc
      301 ttgtgtaacc aaatactact tacaatctgt agaaatcaat aggtgataaa atgattataa
      361 aatatctact ttttgcaatt gtttcagcat taattttatt attttgtaat aaagcattcc
      421 aactaagtaa attacacaag ttcattatat tgtttgtttc attttttata ctaacttttg
      481 tagcatcatt cattagtaga taaaaaataa gatggtgggg ttaacttacc atctttttct
      541 catttaatat ttgtaatatt ttagatactc tttatacttg tgttactgtt atactttgat
      601 taggaaaatt aatacaacat gagttgatga ttatattata aaggaggtat cttctatgaa
      661 ttttaggaat atttatctta tacttatggg attgggaatt ataatattaa ctacaataat
      721 atctttaatt gaaattaaaa ttggtttttg taatgaaaaa tattttaata aattagaatc
      781 aaaatatgga aatatagata gaaaaagaac tattaaacta gaagtacttt atcgatatgt
      841 aacaggtttt gaatatatag caataggatt atttacaaaa agat
//
LOCUS       DAMJVG010000204          825 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.210, whole genome shotgun sequence.
ACCESSION   DAMJVG010000204 DAMJVG010000000
VERSION     DAMJVG010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 825)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 825)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..825
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.210"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            389..>825
                     /locus_tag="PC512_003800"
     CDS             389..>825
                     /locus_tag="PC512_003800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2443453.1"
                     /translation="MIAVKKAYKFRIYPNKKQQELINKTFGCCRFVYNKYLAKRIDVY
                     KNDKETFTYKQCSSDLTNLKKELNWLKEPDKFSLQNALKDLDNAYKKFFKEKAGFPKF
                     KSKKINRFSYKTNFTNGNIMYCGQHIKLPKLGMVKVRDKQVPKG"
BASE COUNT          351 a           93 c          127 g          254 t
ORIGIN      
        1 ctccaaatag gagaaacttc aacgactatt cctcttgagg gaagtacact acaagttatc
       61 ggtagtggaa gtgggtagac cttagcagat aatgccgaag gataagatat agtctgtgct
      121 tatgtgaaag tgtaagaagt tcataagaga actgcatagg tagtagcgaa cttatgtgaa
      181 cgacaacctc aaaaatgata aaagttaaga cttacggttc ttatatatgt tatttaaaat
      241 taaatataaa accttctaaa taattgtttt aaataattac atttgttaac attattatag
      301 gtgattaata aattgttcac cacagcatta tataatatat taaatattaa aatcattaaa
      361 aagtgtatca aaaaacaatt aaagtgaggt gatagcagtg aaaaaagctt ataagtttag
      421 aatatatcct aataaaaaac agcaagagtt aattaacaaa acttttggat gttgtaggtt
      481 tgtatataat aaatatcttg ctaaaagaat agatgtttat aaaaacgata aagaaacttt
      541 tacttataaa cagtgtagtt ctgatttaac caatttaaaa aaagaattaa attggcttaa
      601 agaacctgat aaattttcac tacaaaacgc cttaaaagat ttagataatg catataaaaa
      661 attctttaaa gaaaaggcag gatttcctaa atttaaatca aagaaaatta atagattttc
      721 atataaaact aactttacaa atggaaacat tatgtattgt ggtcaacata taaaactacc
      781 taaacttggt atggttaagg taagggataa acaagtacct aaagg
//
LOCUS       DAMJVG010000205          792 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.211, whole genome shotgun sequence.
ACCESSION   DAMJVG010000205 DAMJVG010000000
VERSION     DAMJVG010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 792)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 792)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..792
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.211"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            539..>792
                     /locus_tag="PC512_003801"
     CDS             539..>792
                     /locus_tag="PC512_003801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2443454.1"
                     /translation="MSGIISVMTQSLILSIMALGVYITYKILDFPDMSADGSYTMGAS
                     IVAFSLTNGISPVVATLMAILCGCTAGLVTGILHIKFKIS"
BASE COUNT          265 a           91 c          111 g          325 t
ORIGIN      
        1 ttatattttt catttttata aaaaaacaat aattaagaat ataactatat tctacatgta
       61 aaaatttttt tatttaaact caattttctg ataatttgat aatttttcaa aatttatagt
      121 tgacttttat tttttactgt attaaactaa ttactataca aaacagaaaa caaaattttc
      181 aaaattatta aattaaaagg agaggtaaat atgaagactt tattaaacaa acaagtacga
      241 ttttttagta gccaatttag ttagggtttg tacctaagtt aagacaaatt gtcataacat
      301 agatacaagc cccttaggat tatgattttt aaggattgta tctatgttgg ctatagtaat
      361 tgttgttaaa gtttttattt tatcatcata atatagagcc acatggatta tactgtgtgg
      421 cttattcgaa tttttgccat acagttatat atactgtgtg gtttttttat atcaaaatca
      481 ttttttaaaa ccaaatttta aaaaccattt aaaatatttt caaaggggtg ttttatttat
      541 gtcaggtatt atatctgtaa tgacgcaaag tttaatttta tcgattatgg cactgggggt
      601 ttatataact tacaaaatct tagattttcc agatatgtct gctgatggta gctatacaat
      661 gggtgcttct attgtagcat tttctcttac taatggtatt tctcctgtag tagcaacttt
      721 aatggctatc ttatgtggtt gtactgctgg tcttgttaca gggattcttc acattaagtt
      781 taagatatct aa
//
LOCUS       DAMJVG010000206          782 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.212, whole genome shotgun sequence.
ACCESSION   DAMJVG010000206 DAMJVG010000000
VERSION     DAMJVG010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 782)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 782)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..782
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.212"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     regulatory      <1..76
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            159..644
                     /locus_tag="PC512_003802"
     CDS             159..644
                     /locus_tag="PC512_003802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HDF2443455.1"
                     /translation="MISELMLKNFRKSSINFKTKIKLNLREKPDINSLKLKSIPEGKI
                     VKLKCVDGIWAEVESNYDKGWLLYKYLERLSNAKNNSNDTIKNRKKNYIGNIRTNGLS
                     LELRNDRTLESKVITTIPDGFKVEVCYSVGKWARVNINKNEKRYSGYVYNQYIEEHLS
                     L"
BASE COUNT          347 a           66 c          123 g          246 t
ORIGIN      
        1 tagataaatc taatgacgca aaactatagg gactaaaatc tttatgtaat aaaggtcatg
       61 tcagccagtt gccaaaaaga taataattct ttttgttaaa agtattttta gagttatata
      121 ttttaataac ttaatatttg gcaagaggag ggcttaagat gatatctgaa ttaatgttaa
      181 aaaattttcg caaatctagc atcaatttta agactaaaat taaattgaat ttaagagaaa
      241 aaccagacat aaatagtttg aaattaaaaa gtataccaga aggtaaaatt gttaagttaa
      301 agtgtgtaga tggaatatgg gcagaagttg agagtaatta tgacaaaggt tggttacttt
      361 ataaatattt agaaagatta agtaatgcta aaaacaatag taatgataca ataaaaaata
      421 gaaaaaagaa ttacatagga aatataagaa caaatggatt aagtttagaa cttagaaatg
      481 atagaacatt agaatctaaa gttataacta caatccctga tggttttaaa gttgaagtat
      541 gttatagcgt tggaaaatgg gcaagagtta atatcaataa aaatgaaaaa cgatattctg
      601 gatatgtata taatcaatac atagaagagc atttaagttt ataatacgat actagcaagc
      661 tttaaatata ttaataaatc gcaaaaaaga atcccattaa tgggattctt ttttgtagaa
      721 acattataac agaactaaag agaataaatt aactaattta tttttattat aaagtaatta
      781 ta
//
LOCUS       DAMJVG010000207          782 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.213, whole genome shotgun sequence.
ACCESSION   DAMJVG010000207 DAMJVG010000000
VERSION     DAMJVG010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 782)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 782)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..782
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.213"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(323..721)
                     /locus_tag="PC512_003803"
     CDS             complement(323..721)
                     /locus_tag="PC512_003803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443456.1"
                     /translation="MNKKKKLIGIAISFLLIISIINPLQVEAEAIIESSVYISSIKEN
                     YTYDNTKFKTIKSKSRHKSRKYNKSKVKLKKRSIRTKKYGYQTINKYKRQNARRHNIL
                     TKLILFIIVIFLVIVLVVLIFIKRKKKKFY"
BASE COUNT          259 a          102 c           61 g          360 t
ORIGIN      
        1 tatactatac atttcttttc atatacaaaa ttctatgaat aattacttta atggtctaat
       61 agtctgctct ttggctctaa ttcttcttat attaattttg tgaataactg ttgatgtaat
      121 tttatatttt gattcatgag gaattaaatt cttcaaagtt aattaagtac atttatcaat
      181 aaatttactt aattaaccat catttaatac tcattcctgt atttatatgc ctcctttgaa
      241 acagaatatt actccatttt aattacatca tattattaaa tagataccaa tgattaaaaa
      301 aatgatattc ttttaattat ttttagtaaa attttttctt ctttctttta ataaatatta
      361 gcactactaa aactataacc aaaaatatga ctattatgaa caatattaat tttgttagga
      421 tattatgtct tcttgcgttt tgtcttttat atttatttat agtttgatat ccatactttt
      481 tagttcttat acttcgtttt ttcaacttta ctttactttt attatatttc ctacttttat
      541 gtctactttt agatttaata gttttaaatt tagtattatc atatgtataa ttctctttta
      601 ttgaagaaat gtatacacta gactcaataa tagcttctgc ttctacttgt aatggattta
      661 taatgctgat tataagtaga aaagatatag ctatcccaat caattttttc ttcttattca
      721 tattttcccc ctcataaaaa tttttaacta gttcattata atatatatat aactaaaaat
      781 ta
//
LOCUS       DAMJVG010000208          778 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.214, whole genome shotgun sequence.
ACCESSION   DAMJVG010000208 DAMJVG010000000
VERSION     DAMJVG010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 778)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 778)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..778
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.214"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            245..>778
                     /gene="dcm"
                     /locus_tag="PC512_003804"
     CDS             245..>778
                     /gene="dcm"
                     /locus_tag="PC512_003804"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HDF2443457.1"
                     /translation="MLTFLDLFAGIGGFRLGMEKAGHKCLGHCEYDKFANLSYNAMHK
                     PKEDEWFERDIREIRTENIPRADVWCFGFPCQDISVAGKQFGFRGERSSLFFTVTKLI
                     RELKEEDRPKYLLIENVKNLLSVNGGFDFLKVLVELDEIGYDAEWQVLNSKNFGVPQN
                     RERIFIVGHFRGRSTRKV"
BASE COUNT          297 a           87 c          164 g          230 t
ORIGIN      
        1 atacagatga tatgtgaaag ttcaaatata gctattatag cagagcgagg aagagttaga
       61 atattagatt tagaaactaa agaaaaatat gatttattaa aaaataaact cgaggaaatg
      121 ttagaagaaa tataagtgaa aatatctaat taagacagtt tagagagtta caaaatatct
      181 tttagtataa attattgttg aagtgttttg tgactctcaa aaatgaaaat aaggaggcgt
      241 tgtattgctt acatttttag atttattcgc agggataggt ggctttaggc tagggatgga
      301 aaaagcagga cataaatgtt tgggacattg cgaatatgat aaattcgcaa atttaagtta
      361 taatgccatg cacaaaccga aggaggatga atggtttgaa agagatatta gagaaattag
      421 aacagaaaat atcccaagag cagatgtctg gtgttttgga ttcccatgtc aagacatttc
      481 tgttgcaggg aaacaatttg gattcagagg agaacgttca agtttatttt ttacagttac
      541 aaaacttatt agagaactca aagaagaaga tagacccaag tatttactta ttgaaaacgt
      601 taaaaatcta cttagtgtta atggaggatt tgatttcctc aaagttctcg ttgaactgga
      661 tgaaatcggc tatgatgcag agtggcaagt tcttaattct aaaaacttcg gagtacccca
      721 aaatagagaa cgaatattca ttgttggaca ttttagagga cgaagtacac gaaaagta
//
LOCUS       DAMJVG010000209          762 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.215, whole genome shotgun sequence.
ACCESSION   DAMJVG010000209 DAMJVG010000000
VERSION     DAMJVG010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 762)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 762)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..762
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.215"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(75..>762)
                     /locus_tag="PC512_003805"
     CDS             complement(75..>762)
                     /locus_tag="PC512_003805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2443458.1"
                     /translation="KKSERVILNDYINTFFYNYNFEYNIKEFENGGDLLKKYPNNVDI
                     IFMDIDLNDENGFNVSKEIKKFDESVRIIFVSSSNKYIKKGYEIGVYRYLEKPLKYSL
                     FKEAISSYLKECYKNEAILSIKCKCKIYFIKVDDILYLEVLKNDLTIHTEKGIYTFKS
                     SMKEIESNLEEHNFFRCHKSYLINLMKVNMLDIENNIVFINQNSIIVSRYKIKLLREK
                     LNSCLVDVII"
BASE COUNT          267 a          103 c           54 g          338 t
ORIGIN      
        1 ttttattata aattttttca tattttacaa tagatatatt ctattagaat agaatataaa
       61 ggcaaaaatt tacctcaaat tattacatct accaaacaac tatttaactt ttctctcaat
      121 aattttatct tataacgact tacaattatt gaattttgat ttataaatac aatattattt
      181 tctatatcta gcatatttac cttcattaaa tttataaggt agcttttatg acatctaaaa
      241 aaattatgtt cttctagatt tgattctatt tctttcatac tactcttaaa agtatatatt
      301 cctttttcag tatgtatagt taaatcattt tttaaaactt ctaaatataa aatatcatct
      361 acctttatga aatatatctt gcatttacat tttatagata aaatagcttc atttttgtag
      421 cattctttta aatatgatga tattgcttct ttaaatagag agtattttaa gggcttctct
      481 aaatatctat aaactcctat ctcataacct ttctttatgt atttatttga tgaggataca
      541 aatataattc ttacactttc atcaaatttt ttgatttctt ttgaaacatt aaatccattt
      601 tcatcattta agtctatatc cataaatatg atatcaacat tattaggata cttttttaat
      661 aaatcgcctc cattttcaaa ctctttgata ttgtattcaa aattgtaatt ataaaaaaag
      721 gtatttatat aatcatttag aattaccctc tctgattttt ta
//
LOCUS       DAMJVG010000210          753 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.216, whole genome shotgun sequence.
ACCESSION   DAMJVG010000210 DAMJVG010000000
VERSION     DAMJVG010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 753)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 753)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..753
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.216"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            63..>753
                     /locus_tag="PC512_003806"
     CDS             63..>753
                     /locus_tag="PC512_003806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2443459.1"
                     /translation="MEKKYFEIHGVPSILWGNPSSKLYIYIHGQCGNKEEAEAFANIA
                     VPHECQVLSVDLPEHGERKREKNSFNPWHVVPELVSIMEYAKCHWNQISLYANSIGAW
                     FSMLSFEKENLRECIFVSPILDMQQLISNMMLWANVSEEQLKHELIIPTSFGHTLSWE
                     YLQYVKQHPITQWNIPTKILYGKHDELTEIGVVEKFVEKFNCNLTIVENGKHWFNTPQ
                     ELNSLYEWLNTL"
BASE COUNT          278 a          105 c          127 g          243 t
ORIGIN      
        1 cattatttta tagtttgatt aatttaataa tcactaatat atcaaactga aaggagattt
       61 ttatggaaaa aaaatatttc gaaattcatg gagttccttc aatcctttgg ggaaatcctt
      121 caagtaaatt atatatttac atacatggac aatgtggcaa taaagaggag gctgaagctt
      181 ttgctaatat tgcagttcca catgagtgtc aagttttaag tgttgatttg cctgaacatg
      241 gagaacgtaa aagagaaaaa aattcattta acccatggca tgttgttcca gaattagtat
      301 ctattatgga atatgcaaag tgccactgga atcaaatttc gttatatgca aatagcattg
      361 gagcatggtt tagtatgtta agctttgaaa aagagaactt aagagagtgt atttttgtat
      421 ctccaattct agatatgcaa cagctcattt caaatatgat gctctgggca aatgtatcag
      481 aagaacagct taaacatgaa ctaattatcc caacttcatt tgggcatact ctttcatggg
      541 aatatctaca atatgtaaaa caacatccta tcactcaatg gaatatacca acaaaaatat
      601 tatatggtaa acatgatgaa cttactgaaa tcggtgttgt agagaaattt gtagaaaagt
      661 ttaattgcaa ccttactatt gtagaaaatg gcaaacattg gtttaacaca ccacaagaat
      721 taaattcatt atatgaatgg ttaaatactt tag
//
LOCUS       DAMJVG010000211          636 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.217, whole genome shotgun sequence.
ACCESSION   DAMJVG010000211 DAMJVG010000000
VERSION     DAMJVG010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 636)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 636)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..636
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.217"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(<1..634)
                     /locus_tag="PC512_003807"
     rRNA            complement(<1..634)
                     /locus_tag="PC512_003807"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          140 a          175 c          117 g          204 t
ORIGIN      
        1 ctacttaacg taactcgttg gcccgttcta caaaaagtac gcggtcacac aagaaatgtg
       61 cttccacagc ttgtaagtgc agggtttcag gttctatttc actcccctcc cggggttctt
      121 ttcacctttc cctcacggta ctatacgcta tcggtcacta ggtagtattt agccttggag
      181 ggtggtccct cctgcttccc acagggtttc acgtgtcccg tggtactctg gatcatatct
      241 aaagtcttct cgtttaacat acaggactat taccttctgt ggtgggtctt tccaaacctc
      301 ttcaattacg atacctcttc gttatgatat gtccgcaacc ccaataaaga aaactttatt
      361 ggtttgggct aatccgcgtt cgctcgccgc tacttacgga atcgaatttc tttctcttcc
      421 ttcaggtact tagatgtttc agttccctga gttcccctca ttaagctatg tattcactta
      481 atgatactta gacattactc taagtgagtt tcctcattcg gaaatcttcg gatcaaagtt
      541 tacgtgcaac tccccgaagc ttatcgcagc ttatcacgtc cttcatcggc tcctagtgcc
      601 aaggcatccg ccctgcaccc ttaataactt gaccag
//
LOCUS       DAMJVG010000212          611 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.218, whole genome shotgun sequence.
ACCESSION   DAMJVG010000212 DAMJVG010000000
VERSION     DAMJVG010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 611)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 611)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..611
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.218"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            <1..>611
                     /locus_tag="PC512_003808"
     rRNA            <1..>611
                     /locus_tag="PC512_003808"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          172 a          126 c          179 g          134 t
ORIGIN      
        1 tttaactgag cgttcagtta cttgacgtag acccgaaacc gggcgaccta cccatgagca
       61 ggatgaagcg aaagtaaaat ttcgtggagg tccgaaccca cgagcgttga aaagctcggg
      121 gatgacttgt gggtagcggt gaaattccaa tcgagcccgg agatagctgg ttctccccga
      181 aatagcttta gggctagcct caaggtgaga gatacggagg tagagcactg aatgtcctag
      241 ggggtattgc acctaccgaa gactatcaaa ctccgaatgc cgtcatctta tacttgggag
      301 tcagactgtg ggtgataaga ttcatagtcg aaagggcaac agcccagatc gtcagctaag
      361 gtccctaaat gtaagttaag tggtaaagga tgtgggattg cacagacaac caggatgttg
      421 gcttagaagc agccactcat tcaaagagtg cgtaatagct cactggtcga gtgatcctgc
      481 gccgaagatt tccggggcta aaacttacta ccgaagctac ggcatcagta atgatgggta
      541 ggggagcttc ccatacgggt tgaagcatga ccgtaaggac atgtggacag tatgggagtg
      601 agaatgttgg c
//
LOCUS       DAMJVG010000213          600 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.219, whole genome shotgun sequence.
ACCESSION   DAMJVG010000213 DAMJVG010000000
VERSION     DAMJVG010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..600
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.219"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            245..358
                     /locus_tag="PC512_003809"
     CDS             245..358
                     /locus_tag="PC512_003809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013483530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF2443460.1"
                     /translation="MIMGRHLWNPSYFVATVLENTEEQIGKYINNQKKQVK"
     gene            360..>600
                     /locus_tag="PC512_003810"
     CDS             360..>600
                     /locus_tag="PC512_003810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2443461.1"
                     /translation="MIVVEKAYKFRMYPNKKQQELINKTFGCCRFVYNKYLAKRIEVY
                     KNDKETFTYKQCSSDLTNLKKELKWLKEPDKFSLQN"
BASE COUNT          255 a           60 c          103 g          182 t
ORIGIN      
        1 tgaaagtgta agaagttcat aagagaactg cataggtagt agcgaactta tgtgaacgac
       61 aacctcaaaa atgataaaag ttaagaactt acggttctta tatatgttat ttaaaaataa
      121 atataaaaaa ccttcaaaat acttgtttta agtaattgca tattttaata ttatgataag
      181 tgatgaaaaa tggaagttac tcatggtaga ggatatgcat atagtatgtc aaatatagac
      241 atccattatt atggggagac atctttggaa tcctagttat ttcgttgcta ctgtattaga
      301 aaatacagag gagcagatag gaaaatatat taataatcag aaaaaacaag taaagtgagg
      361 tgatagtagt ggaaaaagct tataagttta gaatgtatcc aaataaaaaa cagcaagagt
      421 taattaacaa aacttttgga tgttgtagat ttgtatataa taagtatctt gctaaaagaa
      481 tagaagttta taaaaacgat aaagaaactt ttacttataa acagtgtagt tctgatttga
      541 ccaatttaaa aaaagaatta aagtggctta aagaacctga caaattttca ctacaaaacg
//
LOCUS       DAMJVG010000214          591 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.220, whole genome shotgun sequence.
ACCESSION   DAMJVG010000214 DAMJVG010000000
VERSION     DAMJVG010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 591)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 591)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..591
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.220"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            <1..>591
                     /locus_tag="PC512_003811"
     CDS             <1..>591
                     /locus_tag="PC512_003811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HDF2443462.1"
                     /translation="DAFITIVSSIIEIWSCKKVFDYTSQSKTDLKKLNMYFLFSVFLI
                     ISSLYINIGANSRILICIFVMFVFYKSNYKVNIYKCLVISFFYWLILIGINGLSMLLV
                     ATVSNLDNMNVLLSGSLYRYEAIFLGKIMLGILLYVYKASFKNFKISKKEIYICIPMI
                     ANLLSFFVLYDYIINLVKISPERRTAFLVIVLLLIL"
BASE COUNT          206 a           52 c           80 g          253 t
ORIGIN      
        1 tagatgcatt tataacaatt gtttcttcta ttatagaaat atggtcatgt aaaaaagttt
       61 ttgattatac tagtcagtca aagaccgact taaaaaaact aaatatgtat tttctctttt
      121 ctgtttttct cattatttct tctttatata taaatatagg agctaatagt agaatcttga
      181 tatgtatatt tgtaatgttc gttttctata agtctaacta taaggttaat atatataaat
      241 gtctggtaat ctcatttttt tattggttaa tattaatagg tataaatgga ttaagtatgt
      301 tattagtagc aacagtaagc aatttggata atatgaatgt tttacttagt ggcagtttat
      361 atagatatga agcaatattc ttgggaaaga taatgttagg tatattactt tatgtttata
      421 aggcttcttt taaaaatttt aaaataagta aaaaagagat atacatatgt attcctatga
      481 tagcaaattt attgtcattt tttgtacttt atgattatat tattaatctt gtaaaaatct
      541 ctcctgaaag aagaactgct tttttagtaa tagttttact attaatatta t
//
LOCUS       DAMJVG010000215          586 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.221, whole genome shotgun sequence.
ACCESSION   DAMJVG010000215 DAMJVG010000000
VERSION     DAMJVG010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 586)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 586)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..586
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.221"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(382..534)
                     /locus_tag="PC512_003812"
     CDS             complement(382..534)
                     /locus_tag="PC512_003812"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443463.1"
                     /translation="MFEIRHIVLSFLSFISITFFNKIDKTKVKNLIDNETNDTISSDI
                     IVIAYK"
BASE COUNT          230 a           42 c           73 g          241 t
ORIGIN      
        1 aagaatgtat aaggtggtaa atttatataa aaaaggatat gagttgtaaa atattaaata
       61 atattgtact aattggaata attttaactt tattatagat tattttaata ctattagtac
      121 tgatggtgta ttttaaaatt ggtataagca ttacaaatac gaatatgcca actgtaatat
      181 aagtagctat atacatatgt gctgtcccat atattgtatc attgtttata ttaaaaagat
      241 tatgtaaatt ggtatcaatc aataaatcat tttcagaaga aatacctaaa aacttaaaaa
      301 atacctatat gtgtatttag ttagatttga gatttttaca tttaatttta tagtgacaat
      361 attatattat ttttatgatg tctatttata tgcaattact ataatatcag aacttatagt
      421 atcatttgtt tcattatcaa taaggttttt tactttagtt ttgtcaattt tattaaaaaa
      481 agttattgat ataaaagata agaaggataa aactatatga cggatttcaa acataagagt
      541 ggatatttat ataatagata ttttatagtt aattttatta gatttt
//
LOCUS       DAMJVG010000216          577 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.222, whole genome shotgun sequence.
ACCESSION   DAMJVG010000216 DAMJVG010000000
VERSION     DAMJVG010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..577
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.222"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            <1..>577
                     /locus_tag="PC512_003813"
     rRNA            <1..>577
                     /locus_tag="PC512_003813"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          154 a          121 c          190 g          112 t
ORIGIN      
        1 caggatggac ccgcgtctga ttagctagtt ggtaaggtaa cggcttacca aggcgacgat
       61 cagtagccga cctgagaggg tgatcggcca cattggaact gagacacggt ccaaactcct
      121 acgggaggca gcagtgggga atattgcaca atgggcgaaa gcctgatgca gcaacgccgc
      181 gtgagtgatg aaggccttcg ggtcgtaaaa ctctgtcctc aaggaagata atgacggtac
      241 ttgaggagga agccccggct aactacgtgc cagcagccgc ggtaatacgt agggggctag
      301 cgttatccgg atttactggg cgtaaagggt gcgtaggcgg tctttcaagt caggagtgaa
      361 aggctacggc tcaaccgtag taagctcttg aaactgggag acttgagtgc aggagaggag
      421 agtggaattc ctagtgtagc ggtgaaatgc gtagatatta ggaggaacac cagttgcgaa
      481 ggcggctctc tggactgtaa ctgacgctga ggcacgaaag cgtggggagc aaacaggatt
      541 agataccctg gtagtccacg ctgtaaacga tgagtac
//
LOCUS       DAMJVG010000217          572 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.223, whole genome shotgun sequence.
ACCESSION   DAMJVG010000217 DAMJVG010000000
VERSION     DAMJVG010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 572)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 572)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..572
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.223"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            435..>572
                     /locus_tag="PC512_003814"
     CDS             435..>572
                     /locus_tag="PC512_003814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2443464.1"
                     /translation="MIAVKKAYKFRMYPNKKQQELINKTFGCCRFVYNKYLAKRIDVY
                     KN"
BASE COUNT          238 a           64 c           97 g          173 t
ORIGIN      
        1 cctaagtact ttaaaatggg caatcagcag gtaaactccg aacaggagaa acttcaacga
       61 ctattcctct tgagggaagt acactacaag ctattggtag tggaagtggg tagaccttaa
      121 cggataatgc tgaaggataa gatatagtct gtgcttacat gaaaatgtaa gaagttcata
      181 agagaactgc ataggtagta gcgaacttat gtgaacgaca acctcaaaat gataaaagtt
      241 aagacttacg gttcttaaat atgttattta aaattaaata taaaaccttc taaataattg
      301 ttttaaataa ttacatttgt taacattatt ataggtgatt aataaattgt ttaccacagc
      361 attatataat atattaaatg tgataaaatg tgataaaatc attaaaaagt gtatcaaaaa
      421 acaattaaag tgaggtgata gcagtgaaaa aagcttataa gtttagaatg tatccaaata
      481 aaaaacaaca agagttaatt aacaaaactt ttggatgttg tagatttgta tataataagt
      541 atcttgctaa aagaatagat gtttataaaa ac
//
LOCUS       DAMJVG010000218          559 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.224, whole genome shotgun sequence.
ACCESSION   DAMJVG010000218 DAMJVG010000000
VERSION     DAMJVG010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 559)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 559)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..559
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.224"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            163..270
                     /locus_tag="PC512_003815"
     CDS             163..270
                     /locus_tag="PC512_003815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013483530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF2443465.1"
                     /translation="MGRHLWNPSYFVATVSENTEEQIRKYINNQKKQVK"
     gene            272..>559
                     /locus_tag="PC512_003816"
     CDS             272..>559
                     /locus_tag="PC512_003816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2443466.1"
                     /translation="MVVVEKAYKFRMYPNKKQQELINKTFGCCRFVYNKYLAKRIDVY
                     KNNKETFTYKQCSSDLTNLKKELKWLKEPDKFSLQNALKDLDNAYKKFFKEK"
BASE COUNT          242 a           51 c           88 g          178 t
ORIGIN      
        1 ttacggttct tatatatgtt atttaaaaat aaatataaaa aaacttcaaa atacttgttt
       61 taagtaattg tatattttaa tattatgata ggttatgaaa aatggaagtt actcatggta
      121 gaggatatgc atatagtatg tcaaatatag acagccagta ttatggggag acatctttgg
      181 aatcctagtt atttcgttgc tactgtatca gaaaatacag aggagcagat aagaaaatat
      241 attaataatc agaaaaaaca agtaaagtga ggtggtagtg gtggaaaaag cttataagtt
      301 tagaatgtat ccaaataaaa aacaacaaga gttaattaac aaaacttttg gatgttgtag
      361 atttgtatat aataagtatc ttgctaaaag aatagatgtt tataaaaaca ataaagaaac
      421 ttttacttat aaacagtgta gttctgattt aaccaattta aaaaaagaat taaaatggct
      481 taaggaacct gacaaatttt cattacaaaa cgccttaaaa gatttagata atgcatataa
      541 aaaattcttt aaagaaaaa
//
LOCUS       DAMJVG010000219          479 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.225, whole genome shotgun sequence.
ACCESSION   DAMJVG010000219 DAMJVG010000000
VERSION     DAMJVG010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 479)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.225"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            <1..>479
                     /gene="tuf"
                     /locus_tag="PC512_003817"
     CDS             <1..>479
                     /gene="tuf"
                     /locus_tag="PC512_003817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887863.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HDF2443467.1"
                     /translation="ATDGPMPQTREHILLSRQVGVPYIVVFLNKCDMVDDEELLELVE
                     MEVRDLLTEYDFPGDDTPIVRGSALMALEDPKSEWGDKIVELFEQIDEYIPAPERDTD
                     KPFLMPVEDVFSITGRGTVATGRVERGVLKVQDEVELVGLTEAPRKVVVTGVEMFRK"
BASE COUNT          197 a           60 c          116 g          106 t
ORIGIN      
        1 gcaacagatg gaccaatgcc acaaacaaga gagcatatac tattatcaag acaagttgga
       61 gtaccatata tagtagtatt cttaaacaaa tgtgacatgg tagatgatga agagttatta
      121 gagttagtag agatggaagt aagagattta ttaacagaat atgatttccc aggagatgac
      181 actccaatag taagaggttc agcattaatg gcattagaag atccaaagag tgagtgggga
      241 gataagatag tagaattatt cgagcaaata gatgagtata taccagctcc agagagagat
      301 acagataaac cattcttaat gccagtagag gacgtattct caatcacagg aagaggaaca
      361 gttgcaacag gaagagtgga aagaggagta ctaaaagtac aagacgaagt agaattagta
      421 ggattaacag aagcaccaag aaaagtagta gtaacaggag tagagatgtt cagaaaatt
//
LOCUS       DAMJVG010000220          412 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.226, whole genome shotgun sequence.
ACCESSION   DAMJVG010000220 DAMJVG010000000
VERSION     DAMJVG010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 412)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 412)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..412
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.226"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            <1..>412
                     /locus_tag="PC512_003818"
     CDS             <1..>412
                     /locus_tag="PC512_003818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HDF2443468.1"
                     /translation="NPTHSTNRIYDAVGIARCIRSQAGGGGAKTGLYFIDLNKNSKVT
                     INARCLKAKYNAGVTNRNCDNSGVLVNAVLTPDRVNKRQNGRRIKESGETMFTLTAQD
                     KHGILKNGDIRRLTPKECFRLQGFPDKYYERAASV"
BASE COUNT          168 a           48 c           90 g          106 t
ORIGIN      
        1 ataatccaac tcatagtaca aatagaattt atgatgcagt tggaattgct agatgtatta
       61 gaagtcaggc aggaggtgga ggtgctaaaa caggtctata ctttatagac ttaaataaaa
      121 actctaaagt aacaataaat gctagatgcc ttaaagcaaa atataatgca ggtgtgacaa
      181 atagaaattg tgataatagt ggagttttag ttaatgcagt tttaacgccc gatagggtaa
      241 ataaaagaca aaatggtcgt agaattaaag aaagcggaga aacaatgttc acattgacag
      301 ctcaagataa acatggaatt ttgaaaaatg gagatataag aaggttaaca ccaaaggaat
      361 gctttaggtt gcaaggattt ccggataaat attacgaaag agcagcaagt gt
//
LOCUS       DAMJVG010000221          411 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.227, whole genome shotgun sequence.
ACCESSION   DAMJVG010000221 DAMJVG010000000
VERSION     DAMJVG010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 411)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 411)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..411
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.227"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            65..346
                     /locus_tag="PC512_003819"
     CDS             65..346
                     /locus_tag="PC512_003819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443469.1"
                     /translation="MASKQTPRNNLEKFLRIRVLSHTGDKIHIKLPVNFAKRMIENNA
                     LDLFNGKDDVVDGKKVTEILVKAFDYDLTGEVVHLERKNGDIIKVSIVQ"
BASE COUNT          183 a           26 c           67 g          135 t
ORIGIN      
        1 taaagatatt tttaagaata aaatttatta ttaaataaaa aataaaggag agtgatttaa
       61 tagtatggca tcaaaacaaa caccaagaaa caatttagaa aagtttttaa gaataagagt
      121 attatcacat acaggcgata aaatacatat aaagttacct gtaaattttg caaagagaat
      181 gattgagaat aatgccttgg atttatttaa tggaaaagat gatgtagtag atggtaaaaa
      241 agttactgaa atattagtta aggcatttga ctatgattta actggagaag tagttcactt
      301 ggagagaaaa aatggagaca ttattaaagt ttcaattgta caatagaatt attttatatg
      361 aattttattt ttgaatagtt ataaataatt agaaatttgt aaaaaagtat a
//
LOCUS       DAMJVG010000222          405 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.228, whole genome shotgun sequence.
ACCESSION   DAMJVG010000222 DAMJVG010000000
VERSION     DAMJVG010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 405)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 405)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..405
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.228"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            <1..215
                     /locus_tag="PC512_003820"
     CDS             <1..215
                     /locus_tag="PC512_003820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDF2443470.1"
                     /translation="IGSHPSFQLFHDLVTMFNISVDEYFYPAEKVAKSTARRQIETSL
                     DLLSDNELKIIQGTIDGILNSRENKK"
BASE COUNT          125 a           73 c           68 g          139 t
ORIGIN      
        1 atatcggttc acacccaagt tttcaattat tccatgattt agttaccatg ttcaatatat
       61 cggttgatga atatttctat ccagcagaga aagttgcaaa aagcacagct cgccgtcaga
      121 tagaaacatc acttgattta ttgagtgata acgaattaaa aattattcaa ggtacgattg
      181 acggtatctt gaacagcagg gagaataaga agtaatcagc ttcttgtttt ccccgttttc
      241 tttttagcca tatttcttca agacttattt gttgatctgc tttgcaggaa acaaataaga
      301 gccgacaatc tataagttac aataacctac aaattatcgg ctctgcgtct tagcgtctgg
      361 ctctttgata atagttactt ttccatgctt tatattgatt aaagt
//
LOCUS       DAMJVG010000223          399 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.229, whole genome shotgun sequence.
ACCESSION   DAMJVG010000223 DAMJVG010000000
VERSION     DAMJVG010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 399)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 399)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..399
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.229"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            154..270
                     /gene="rrf"
                     /locus_tag="PC512_003821"
     rRNA            154..270
                     /gene="rrf"
                     /locus_tag="PC512_003821"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            276..364
                     /locus_tag="PC512_003822"
     tRNA            276..364
                     /locus_tag="PC512_003822"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:310..312,aa:Leu,seq:taa)
BASE COUNT          133 a           69 c           86 g          111 t
ORIGIN      
        1 taactctata tttttaaact tgtcaaaact tatggatttt taatagtttt ataaggcaaa
       61 aaatcgaata aaaaaagtat tgacacaata agacaaagat gttattataa tacttgtctt
      121 agaaaaaaag ttaaatgaaa atttagacaa taatctggtt ataatagcag agaggataca
      181 cctgttccca ttccgaacac agaagttaag ctctctagcg ctgatggtac ttggtgggaa
      241 actgcctggg agagtaggac atagccaggt gatgtgccga agtggcggaa ctggcagacg
      301 cacaggactt aaaatcctgc gggacttacc tctcgtaccg gttcgattcc ggtcttcggc
      361 accacaaatt attgtgggcc attagctcag ttggttaga
//
LOCUS       DAMJVG010000224          381 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.230, whole genome shotgun sequence.
ACCESSION   DAMJVG010000224 DAMJVG010000000
VERSION     DAMJVG010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..381
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.230"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(<1..>381)
                     /locus_tag="PC512_003823"
     rRNA            complement(<1..>381)
                     /locus_tag="PC512_003823"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT           89 a          107 c           87 g           98 t
ORIGIN      
        1 tgtactaccc attgtagcac gtgtgtagcc ctaagcataa ggggcatgat gatttgacgt
       61 catccccacc ttcctccagg ttatccctgg cagtctctct agagtgccca acttaatgat
      121 ggcaactaaa gacaagggtt gcgctcgttg cgggacttaa cccaacatct cacgacacga
      181 gctgacgaca accatgcacc acctgtcacc aatgtccccg aagggaactc tccgattaag
      241 gagatgtcat tgggatgtca agcttaggta aggttcttcg cgttgcttcg aattaaacca
      301 catgctccgc tacttgtgcg ggtccccgtc aattcctttg agtttcactc ttgcgagcgt
      361 acttcccagg cggagtactt a
//
LOCUS       DAMJVG010000225          364 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.231, whole genome shotgun sequence.
ACCESSION   DAMJVG010000225 DAMJVG010000000
VERSION     DAMJVG010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..364
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.231"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            168..284
                     /gene="rrf"
                     /locus_tag="PC512_003824"
     rRNA            168..284
                     /gene="rrf"
                     /locus_tag="PC512_003824"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            291..362
                     /locus_tag="PC512_003825"
     tRNA            291..362
                     /locus_tag="PC512_003825"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:323..325,aa:Asn,seq:gtt)
BASE COUNT          117 a           61 c           78 g          108 t
ORIGIN      
        1 attcattaag atatatgtgc agtttttaga gtgttaactc tatgtaaagt actaacttca
       61 attgatgaag tatatatcgt aaaaacaatt actatttagt acttcaaaac tattgacatt
      121 taaaaataaa gatgttaata taatacttgt cttataaata ggcaatatgt ggttataata
      181 gcaaagagga tacacctgtt cccattccga acacagaagt taagctcttt agcgctgatg
      241 gtacttggtg ggaaactgcc tgggagagta ggacgtagcc acgtgaatat tccaaggtag
      301 ctcaatggtg gagcaaccgg ctgttaaccg gtaggctgtg ggttcgagcc ccacccttgg
      361 agcc
//
LOCUS       DAMJVG010000226          344 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.232, whole genome shotgun sequence.
ACCESSION   DAMJVG010000226 DAMJVG010000000
VERSION     DAMJVG010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 344)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 344)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..344
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.232"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(<1..288)
                     /locus_tag="PC512_003826"
     CDS             complement(<1..288)
                     /locus_tag="PC512_003826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443471.1"
                     /translation="MISMIMMLIGVLFIVFGIILTAVEIKGKMPGFYGVGQNAVRKNA
                     IGIIAAGIALIFFRNGLDSIDSILTYGVFLVIELVVIGLYFLIRIKYDKDGN"
BASE COUNT          130 a           73 c           19 g          122 t
ORIGIN      
        1 attcccatct ttatcatatt ttattcttat aagaaaatat aatcctatta ctactaactc
       61 tatcactaaa aatactccat aggtaagaat tgaatcaata ctatctaacc catttctaaa
      121 aaaaattaat gctatacctg ctgctataat ccctatagca ttttttctta ctgcattttg
      181 cccaactcca taaaaacctg gcatttttcc ttttatttcg acagcagtta aaattatccc
      241 aaacactata aataatactc caataagcat cataatcata ctaatcatct aattacctcc
      301 ttcacttaag gaaatttcaa tttctaaaat ctaaaataaa taat
//
LOCUS       DAMJVG010000227          328 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.233, whole genome shotgun sequence.
ACCESSION   DAMJVG010000227 DAMJVG010000000
VERSION     DAMJVG010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 328)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 328)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..328
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.233"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
BASE COUNT          143 a           31 c           35 g          119 t
ORIGIN      
        1 gtcattaaat atgccaatag ttttatatat tattgatttt attaaaaaaa gagatataca
       61 aactaataag ttgtaatctc tcaaatataa aaaaacaata aattagctca ttggattttt
      121 tagtccataa tataattata gattattcac caaacaatct atagaaattg tggtattaat
      181 gtttaaataa ccaacttttt ctaaaataac ctttatagga atatatgagt tcataagtaa
      241 agatagcgaa ataagaaacc agtttggtat gtaaaatcta gatttttaat taaattatca
      301 agattatata ttatagtatc aaaaatag
//
LOCUS       DAMJVG010000228          301 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.234, whole genome shotgun sequence.
ACCESSION   DAMJVG010000228 DAMJVG010000000
VERSION     DAMJVG010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 301)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 301)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..301
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.234"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
BASE COUNT          117 a           38 c           41 g          105 t
ORIGIN      
        1 tatgtaagaa ccgtaggaac tacggggatt gcctgtggag aattagtaag acatatttta
       61 gtatgcaaaa ttctatgaag caggaaccct gtgactttag tcatgggagg ttcagtttag
      121 cttaaaactt acttatctat ttcagtttct attagaatta ttattagact cattaaaata
      181 aaagcactaa tataactaat aatatatgtt aaattcatta actctacata aagttttaca
      241 atctaaatga aatacaataa tctgcataaa attcaatagc ttatataaaa tttaataatt
      301 t
//
LOCUS       DAMJVG010000229          297 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.235, whole genome shotgun sequence.
ACCESSION   DAMJVG010000229 DAMJVG010000000
VERSION     DAMJVG010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 297)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 297)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..297
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.235"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            <1..>297
                     /locus_tag="PC512_003827"
     CDS             <1..>297
                     /locus_tag="PC512_003827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002590471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="peptidase dimerization domain-containing
                     protein"
                     /protein_id="HDF2443472.1"
                     /translation="IQKIQQLVPPTHPVLGDGILVLTDIKSSPYPGASVVPDYCKATF
                     DRRLLVGETREGVLAPIQALLDEMMKEDPELNAKVSYAVEKADCYTGNTIESER"
BASE COUNT          117 a           43 c           54 g           83 t
ORIGIN      
        1 aatccaaaag atacaacaat tagtacctcc aactcatcca gttttaggtg atggaatatt
       61 agttttaaca gatataaaat cttctccata tccaggagca tcagtagtgc cagattattg
      121 caaagctact tttgatagaa gattattagt tggagaaaca agagaaggcg tattagctcc
      181 aatacaagct ttattagatg aaatgatgaa agaagaccca gaattaaatg caaaagtttc
      241 ttatgcagtt gaaaaagctg attgctatac aggaaatact atagaaagtg aaagatt
//
LOCUS       DAMJVG010000230          252 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.238, whole genome shotgun sequence.
ACCESSION   DAMJVG010000230 DAMJVG010000000
VERSION     DAMJVG010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 252)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 252)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..252
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.238"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
BASE COUNT          111 a           18 c           51 g           72 t
ORIGIN      
        1 actgcaaatg ttgtatatga aatagcaaaa agaatgggct aaaagttgca aaatgtcttt
       61 tagtatgaat atttttgaag tgttttgtaa ctctcaaaaa tgaaaataag gggtgggata
      121 aatgtatgaa tatatattaa gatggcaaat aggattatcg ttagaaaata gaaaaataca
      181 ttatacatat ggaagtaaag aagctttaag aaagaaagca aaggcattgg ctaaagatga
      241 aaatatagta ct
//
LOCUS       DAMJVG010000231          213 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.240, whole genome shotgun sequence.
ACCESSION   DAMJVG010000231 DAMJVG010000000
VERSION     DAMJVG010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 213)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 213)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..213
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.240"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(<1..>213)
                     /locus_tag="PC512_003828"
     CDS             complement(<1..>213)
                     /locus_tag="PC512_003828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2443473.1"
                     /translation="SLMAQFLGFSDVNMGIGTLVLGIASIIIGITLFKKFTFIKDTTA
                     IIVGSFIYQFTIYFAMSLGMLSTDLKL"
BASE COUNT           83 a           33 c           31 g           66 t
ORIGIN      
        1 tagttttaag tcagttgata acattcctaa actcattgca aagtatatag tgaattggta
       61 tataaaagag ccaacaatta ttgcagtagt atctttgata aaagtaaatt tcttaaatag
      121 tgtaatacca attatgatag aggcaattcc aagaactaaa gttcctatac ccatatttac
      181 atctgagaat cccaagaact gagccataag act
//
LOCUS       DAMJVG010000232          206 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.denovo.241, whole genome shotgun sequence.
ACCESSION   DAMJVG010000232 DAMJVG010000000
VERSION     DAMJVG010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 206)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 206)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..206
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.denovo.241"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(<1..167)
                     /locus_tag="PC512_003829"
     rRNA            complement(<1..167)
                     /locus_tag="PC512_003829"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT           52 a           55 c           39 g           60 t
ORIGIN      
        1 ttatcccgta ttagcatacc tttcggtatg ttatccgtgt gtacagggta ggttacccac
       61 gcgttactca cccgtccgcc gctctttacc gaagtaaatc gctcaacttg catgtgttag
      121 gcacgccgcc agcgttcatc ctgagccagg atcaaactct caaataaaag tttatcaggc
      181 tcagatacta ttgttatcaa aatatc
//
LOCUS       DAMJVG010000233        18286 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.guided.084, whole genome shotgun sequence.
ACCESSION   DAMJVG010000233 DAMJVG010000000
VERSION     DAMJVG010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18286)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18286)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18286
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.guided.084"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(<1..664)
                     /gene="bclA1"
                     /locus_tag="PC512_003830"
     CDS             complement(<1..664)
                     /gene="bclA1"
                     /locus_tag="PC512_003830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA1"
                     /protein_id="HDF2443474.1"
                     /translation="MRNIILYLNDDTFISKKYPDKNFSNLDYCLIGSKCSNSFVKEKL
                     ITFFKVRIPDILKDKSILKAELFIHIDSNKNHIFKEKVDIEIKRISEYYNLRTITWND
                     RVSMENIRGYLPIGISDTSNYICLNITGTIKAWAMNKYPNYGLALSLNYPYQILEFTS
                     SRGCNKPYILVTFEDRIIDNCYPKCECLPIRITGPMGPRGATGSTGPTGVTGPTGSTG
                     ATG"
     gene            complement(1342..1866)
                     /locus_tag="PC512_003831"
     CDS             complement(1342..1866)
                     /locus_tag="PC512_003831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDF2443475.1"
                     /translation="MENKNPIVTIEMENGKEIKIELYPNIAPNTVKNFVSLVNEGYYN
                     GIIFHRVIPGFMIQGGCPNGTGMGGPGHSIKGEFSGNGFTNNLKHERGVISMARTMAP
                     NSAGSQFFIMHKNSPHLDGQYAGFGRVIEGMDTVDEIASVRTDSADKPQTPQIMKSVT
                     VETFGIDYSDVEKN"
     gene            complement(1931..2683)
                     /locus_tag="PC512_003832"
     CDS             complement(1931..2683)
                     /locus_tag="PC512_003832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HDF2443476.1"
                     /translation="MKLGLCLEGGGAKGAYQAGVVKALYDGGINKFYSISGTSIGAIN
                     GYYLYTGNVDNLEKMWTNIKDIQNGNVKIVNNTVDNSPAIDNLRELDDSNIEEMNFYV
                     NYVEVDNKVVSEKIVDVSKMPRNEAIISISYSGLLPSNPNATLGFKEQFVKDVQEGIY
                     DGFKLDGGLIRSALIEPLIGDNVDKIILISTKYNYELPEDIKKVYDEDKIIVVRPNTQ
                     FAPKDTLNFDDEFCKTIYQEGYEIGKNILDRL"
     gene            complement(2714..4012)
                     /locus_tag="PC512_003833"
     CDS             complement(2714..4012)
                     /locus_tag="PC512_003833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M18 family aminopeptidase"
                     /protein_id="HDF2443477.1"
                     /translation="MDSINFAKNLIDFIYDSPSSFHAVKSTKEILDKNGFEELVLNQR
                     WNLRVGGKYYVTKNLSAIVAFVVNSEDIERDGFRIIGSHSDSPTFSIKPNAEIEAEKS
                     YLKLNTECYGGAILSTWLDRPLGIAGRVVLKGDSILKPNERLIDFKKPICIIPNLAIH
                     LNRSINDGHSYNKQKDMLPLVGMLNDTLEKDNFLIKQIASNLDVNMDDIIDFDLFLYE
                     FEKGSLIGANDEFISIGRQDNLAMVHASLNALVNTKGQHGVNVMAVFDNEEVGSSTKQ
                     GADSNMLLNILERICISMGKDREGFFESIYSSFMISSDLAHAIHPNIPEKHDPTNKPI
                     MGKGPVIKINASQAYTSDGYSIAIYKNICREANVEYQEFVNRSDERGGSTIGPISSTH
                     IDIPSVDVGSPILAMHSIRELGNVEDHYSIYKTFSKFFEI"
     gene            complement(4029..6293)
                     /locus_tag="PC512_003834"
     CDS             complement(4029..6293)
                     /locus_tag="PC512_003834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3553 domain-containing protein"
                     /protein_id="HDF2443478.1"
                     /translation="MNLDTLNPAQREAVEKTEGPVLILAGAGSGKTKVLTTRIAYLIE
                     DKGVQAPNILAITFTNKAANEMRERVEQNIGPETKDMWISTFHSCCVRILRKDINKIG
                     YNRSFVIYDSADQVTLVKDCLKELNLSDKVFEPKAVISAISGAKDKLYTPKQFKDINM
                     ADNRMVKIADIYALYQDRLKRNSALDFDDLILKTVELFKANDEVLAYYRSRFRYIMVD
                     EYQDTSKAQYELIKLLAREHQNICVVGDDDQSIYGWRGADIRNILEFEKDYDNVHVVK
                     LEQNYRSTQVILDAANKVISNNIERKRKKLWSEKKEGELIKIQLTGSEIEEADFIADS
                     IAQIARKENRPYKDFAVLYRANAQARPVEDALNRSQIPYNIYGGTKFYERKEIKDLLA
                     YLRVIQNPQDDISIKRIINVPRRGIGLRTIEKIEDRANLKQESIYSVLIDIETNSDIS
                     TKARASISGFVDIIGTLRTIKEVYPVSKLIEKVLDTTGYMDELVEIRNKNEKDLTGKG
                     EEAQDRIDNLREFISIALEFESSNDDTYENKDLETFLTSIALTSESNDEEDNDRVSLM
                     TIHTSKGLEFPVVFLTGMEEGLFPISRAIKSMSDSQIEEERRLCYVGITRAKEELYMS
                     LTEKRTLYGKTNVAIASRFMEELPEECIERLYKVKKELSYSKASYNMLDKYTKKYMST
                     ISKSKVADKVNATIKDSNKETNPDDIKLGSKVHHPKFGVGTVVSIIGTDVTIAFDQQG
                     IKKINKEYTTLNIL"
     gene            complement(6548..7366)
                     /locus_tag="PC512_003835"
     CDS             complement(6548..7366)
                     /locus_tag="PC512_003835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HDF2443479.1"
                     /translation="MFKINNLTYQYEKNTNALLNINMDFSKGNVIGIIGSNGSGKSTL
                     FMNLMGILKPTSGEILFKEEKLKYDKRSLYNLRKNVGIVFQDPEKQIFYSKVYDDIAF
                     AMRNIGMDEKTIKERINKALVAVNGIDFIDRPVHFLSYGQKKRVAIASVIAMENEIVL
                     LDEPTAGLDPVSTRSIVDIIKGLNKNNIKIVISSHDMNLMYEICDYIYVLDKGILIDE
                     GKAENVFINENNIIQAGLESPWLVKVHRNMNLPLFKKEEDLYKYWKERELNTNK"
     gene            complement(7359..8057)
                     /gene="cbiQ"
                     /locus_tag="PC512_003836"
     CDS             complement(7359..8057)
                     /gene="cbiQ"
                     /locus_tag="PC512_003836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ECF transporter T component CbiQ"
                     /protein_id="HDF2443480.1"
                     /translation="MLIIDKYAYTNRLSKVNPNKKVAIGVIFLIASMVIQNIFILSGI
                     MILMSILVVCVAGIDLKNYLKLLRIPMYFLFLSIGITLVNISFNKADLLYSFEFFSFN
                     VGISKASIDMSIHVLFRAMSCLTCVYFCILTTPFNQLIFFFKKLHLPDTFVELSMLIY
                     RFIFIFLEEFSEIYKSQELRFGYINLKTSYKSLGILGSMLYKRLMTRYDDMCISLDIK
                     LYDGKFHIVGDNDV"
     gene            complement(8060..8338)
                     /locus_tag="PC512_003837"
     CDS             complement(8060..8338)
                     /locus_tag="PC512_003837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF2443481.1"
                     /translation="MSAKTKTNILLLLLVVALIIFPLLVNSGAEYGGADGQAESEITK
                     INPNYKPWFSSPYEPPSGEIESLLFSAQAALGAGVIGYILGLQKGKRS"
     gene            complement(8328..9080)
                     /locus_tag="PC512_003838"
     CDS             complement(8328..9080)
                     /locus_tag="PC512_003838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter permease"
                     /protein_id="HDF2443482.1"
                     /translation="MKQNIKLGVIAALMLIILTPVTSNAMHIMEGYLPVKWSIAWGVI
                     FIPFFLFGLKSIGKIVKQDPKKKVLLALCGAFVFVLSALKIPSVTGSCSHPTGVGLGA
                     IMFGPSVMFVLGTIVLIFQALLLAHGGITTLGANAFSMAIIGPIVSFLIFKALKKKDG
                     NNAIPVFLAAAIGDLATYTITSIQLALAFPDPSGGVMASAIKFLGIFFMTQIPIAIAE
                     GILTVIVYNLITENGEKSILENNDKGVKANEC"
     regulatory      complement(9262..9454)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            complement(9586..11358)
                     /locus_tag="PC512_003839"
     CDS             complement(9586..11358)
                     /locus_tag="PC512_003839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide reductase activation-like protein"
                     /protein_id="HDF2443483.1"
                     /translation="MKWIYDDYEFENRANNLSWTIAGDYNESIDISEKDYSSKEIGLY
                     FAIIAGARRKYVDWDIVKKYLTNRIRKGYNKDIILGLIQVILNTIVEEKVIKDRPGIE
                     DIRRNAYKDIVSRFTKIHNDNIMDKIKYTFVLYSMDKHPALDSMTRRIVNDIRNIDTN
                     QDIMEILKALDVIYLTYFEYILNGEENSLIDENNVESVEVNFDTFADFMYEELYSDEE
                     ENIIESDIDSISSSMLVEGVGDFDDSKCSNSADRVIYVDEDTANKIYSKIEHYYGKTY
                     LSKGEIKKIETQNCRNVHEGCRIHFTDGVLRSECNNVFQLKYVTRQKENNLGKFREHA
                     RMYRQQIKRLKESLSRILIEENAKSRVYSDCGTILANRAWRVGRSNNNKIFYKDIENE
                     KGKYVIDILLDASGSQSRNQGNVAIQAYIIANALTEVGIPNRVMGFSSFLDYTILKRF
                     KDYDDSIKNSENIFEYFCAGNNRDGLAIKSICSGLINRDEENKILIVLSDGRPNDVKI
                     GKSSERTLRGEKAYRGIVGLRDTANEVRKARKQNILVLGVFTGKESELEAERLIYGND
                     FIYSRDITRFSDVVSMYLKKIIRN"
     gene            complement(11372..12301)
                     /locus_tag="PC512_003840"
     CDS             complement(11372..12301)
                     /locus_tag="PC512_003840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2443484.1"
                     /translation="MDIIDNLRVQGVDEKLIEDVLYFRNYYGLEKDLEYRVTKSKTYF
                     YGKDILSMCIAAILEEENILLSGPKATGKNLLADNLGEIFNRPQWNTSFHINTDSSTL
                     IGTDTFIDNEVKLRRGSVYECAINGGFGVFDEINMAKNDAIVVVHSALDYRRIIDVPG
                     YERVNLHPATRFIGTMNYEYAGTKELNEALVSRFMVIDIPPIEEDKLMMILKNEFSDA
                     DEEKLIHFAGIFLDLQLKSQNGEISSKAIDLRGLMASLKTIRRGLKPTLAINMGLTGK
                     TFDVYEKEMVGDVIKTRIPNKWESIDVFPISHI"
     gene            12530..12718
                     /locus_tag="PC512_003841"
     CDS             12530..12718
                     /locus_tag="PC512_003841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2443485.1"
                     /translation="MEYMSCPEVAKKWGISERRVQKLCEESRIPGVSKLGYMWLIPKN
                     AEKPVDGRTKRRKEVQYE"
     gene            12711..13412
                     /locus_tag="PC512_003842"
     CDS             12711..13412
                     /locus_tag="PC512_003842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2443486.1"
                     /translation="MNSVLIIDDDKELCALMKKCVEQENLSAITAHGGAEGLHLVDKN
                     RHTLSLVILDIMMPDIDGFQVLKKIRETSNIPVIMLTAKNDEDDKVSGLRLGADDYLT
                     KPFSINELMARVNSLIRRYTMLNPAFITDTDFIIINGMIIDKTNRIVSVNNIPVQLTS
                     KEFDLLAFLASNKGRVFTKKQIYTQVWEEEYAFDDSNIMSFISKLRKKIEPDPNHPFY
                     ILTVRGVGYRFNKEA"
     gene            13414..14337
                     /locus_tag="PC512_003843"
     CDS             13414..14337
                     /locus_tag="PC512_003843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2443487.1"
                     /translation="MNTSVYLLLILALSLIIIAYLVSVLLRVRIQLTLIKDALEDIKN
                     GNLNRRILTDENDITKQICYDINEIAINSQFQLIQQKQSEQAYKQLMTSLSHDVKTPL
                     ASLVGYLEAVESKIVVGEEKDEYIHVASNKAHYLKNFVENLFEWVKLDSKEQVFHFDI
                     FDLNELSRNIISDWIPVLESSHFEYEFDIPEIEYFLRIDANAYTRIINNLLQNIITHS
                     SGNKMTLRIFENKEQAQIIITDNGKGISSDNLPHIFERLYQCDHSRASKGNGLGLAIA
                     KELINAHKGNITANSTPGMGTEFTILLPKAL"
     gene            14494..15417
                     /locus_tag="PC512_003844"
     CDS             14494..15417
                     /locus_tag="PC512_003844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019639192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2443488.1"
                     /translation="MNDFVIETKQLTKIYGNQTVVDKVNLHVKKGRIYGLLGRNGAGK
                     TTIMKMILGLTSITYGEVDVFGENIKGREKQVYPRIGAIIETPGFYPNLTGTENLEIF
                     AKLRGTAAPNSVKRALEIVGLPYKNKKLFSKYSLGMKQRLGIANAILHDPELLVLDEP
                     TNGLDPIGIAEMRKFIRDLSVEHGKTILISSHILSEISLLADDIGIIDHGVLLEESSM
                     SELEKKNSKYILLQVSDIPKTSLILERQFNTKDYSVQDDYTLHLYNTNLDMGEINKAL
                     VMQNVTVISSQLCNDTLEDYFKKITGGEGIA"
     gene            15410..16147
                     /locus_tag="PC512_003845"
     CDS             15410..16147
                     /locus_tag="PC512_003845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2443489.1"
                     /translation="MLKLIQTEFLKLRRRKLIWLMLLSALIMPFFALLYFNYFGKTGV
                     EPIKFYKWSAFGYTLWIILPVVLGIFCTMLIHEENQYDMLKQLWIVPISKMGYFFSKF
                     FVVLIYSICFMLITAVASVLFSVLSGYVVFSWASILYLLKKCLEIGVITAFVMLPILA
                     IATSQKGYILPICITLVYAFSGFVIMTINMYLHPLSSMGVIIMRNKDIPGLIFSQEIN
                     VPLAFLCICIWSIVSVLFANIALGRRK"
     gene            16158..16931
                     /locus_tag="PC512_003846"
     CDS             16158..16931
                     /locus_tag="PC512_003846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2443490.1"
                     /translation="MWKLLWAECQKIRRSKIVWITVFASIMIAVIVFAGGQDVYNDPD
                     LHYGLKSVYDGSRYIDNAGWYMDAVQPWSTFFVLPAVIALLGSYIICREEEEDTIKSL
                     RLIPINETNLTIAKMIITFIFSILLYLLLFTITFLTESVLHFSDLSTKLVLSCMKEYF
                     LDGIGVFFAISPIIALVSRMKKGYWLALVFTEVYSIAGLFAGMSNVLQTFFPIAAIFN
                     ISGYYITTGEKIMGSIMSLLLCACLSAFILKGLKHNEKN"
     gene            complement(17472..18080)
                     /locus_tag="PC512_003847"
     CDS             complement(17472..18080)
                     /locus_tag="PC512_003847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HDF2443491.1"
                     /translation="MSVINSFILQYGLISVFVLIMIEYACFPLPSEVVLPLCGAIAAR
                     NHFGFLTILILSIIAGILGSIFCYTVGNWGGKSIINKIIEICPKAKKGIFASQDYFNK
                     YSSISVCVCRLIPLCRTYISFIAGIAGQNIITFVISSIVGITIWNTSLISIGYIFSES
                     WVRIMSHYNDYKFLVLIIPISIIFIGFVIKSFIHKKHHKIRL"
BASE COUNT         5933 a         3132 c         2267 g         6954 t
ORIGIN      
        1 ttcctgtcgc tcctgtactt ccggttgggc ctgttactcc tgttgggcct gtacttcctg
       61 tcgctcctct tggtcccatt ggacctgtaa ttctaattgg aagacactca catttaggat
      121 aacaattatc tataattcta tcttcaaatg ttacaagtat atacggtttg ttacaacctc
      181 tactagatgt aaattcaaga atctgataag ggtaatttaa agataaagct aacccataat
      241 taggatattt attcattgcc catgctttta tagttcccgt aatatttaaa caaatatagt
      301 tggatgtatc acttatccca attggtaaat atcccctgat attttccata gacactctat
      361 cattccatgt tatagttcgt aaattataat attcacttat tcttttaatt tcaatatcta
      421 ctttttcttt aaaaatatga ttcttatttg aatcaatatg aataaataac tctgctttta
      481 atatactttt gtcttttaat atatctggta ttctcacttt aaaaaaagta atcaactttt
      541 cttttacaaa actatttgaa catttacttc ctattaagca ataatctaaa ttactaaagt
      601 ttttatctgg atatttttta gatataaaag tatcatcatt taaataaagt ataatatttc
      661 tcatttataa tccctccatt ttgggtctat atcatactat gtttaaaata catgcttagt
      721 tacaatacaa ttaaaattta tagtattaaa tttttatata ataatgctga tttctacaaa
      781 aaaagaacat gtcattagaa atttctaata gcatgttctt tttcattatt atatattaca
      841 ctttaaatta ttccttgact ggcttagctg gtgtaaacta aaccagtctt tctaaaatat
      901 taagcacttt tttcttatta tgttttttag gatttattgt ctatattatt gtaaaccaaa
      961 gttataaaat tgtaaataga atatattacc ataacaatat ttttttataa gtaaaaatta
     1021 taaaaaactt tatttttgtt aaatggaata aataaaataa gtttaaaaaa tactgaaata
     1081 agtgttttcc acatatttta tatatttatt taatacatta ttatttaaaa ataaatatat
     1141 aaacaatcat aataaaattt ttttaataaa actttatttt ttagttaaaa tcatacaata
     1201 tatagatttc cacaatacaa ataaattaaa aagtgaaatg tatttgtcta aaaacataat
     1261 aacatttcac tttatcctca tttttaagta atatatattt ttaattttta tttataacta
     1321 aatctagttt ttatataaat tttagttttt ttctacatct gagtaatcta ttccaaaagt
     1381 ttctacagta acagatttca taatttgtgg agtttgtggc ttatcagctg aatctgttct
     1441 aactgatgct atttcatcaa ctgtatccat accttctatc actctaccaa aacctgcata
     1501 ctgaccatct aagtgtggtg agtttttatg cattatgaaa aattgagaac cagctgaatt
     1561 aggtgccata gttctagcca ttgatatgac tcctctttca tgttttaaat tgttagtaaa
     1621 tccattacca ctaaattcac cttttattga gtgacctgga ccacccattc ctgtaccatt
     1681 tgggcatcct ccttgtatca taaatcctgg tattactcta tgaaatatta ttccattgta
     1741 atatccttca tttactaatg atacaaagtt tttaactgta tttggagcta tatttggata
     1801 taactcaatt ttgatttctt ttccattttc catttctata gttactatag gatttttatt
     1861 ttccataatt tattaccttc cttttcatta gttaaattac ataattacat ttattatatt
     1921 atactctaaa ttaaagtcta tcaagtatat tttttcctat ttcatatcct tcttgataaa
     1981 tagttttaca aaactcatca tcaaagttaa gcgtgtcttt aggagcaaat tgagtattag
     2041 gtctaactac tattatttta tcttcatcat atactttttt aatatcttct ggcaactcat
     2101 aattatattt tgtggatatt aaaataattt tatccacatt atccccaatt aatggttcaa
     2161 ttaatgcact cctaattaaa cctccatcta atttgaaacc atcataaatt ccttcttgca
     2221 catctttcac aaattgttct ttaaatccaa gagttgcgtt tggatttgat ggtaacaacc
     2281 cactgtatga aatgctgata atggcttcat tacgaggcat ttttgataca tcaacaatct
     2341 tttctgatac tactttatta tcaacttcaa cataattaac ataaaagttc atttcttcta
     2401 tattactatc atctagttcc cttaggttgt ctatagcagg agaattatcc acagtattat
     2461 ttactatttt tacatttcca ttctggatat cttttatatt tgtccacatt ttctccaagt
     2521 tatcaacatt ccctgtgtac aaataatatc catttattgc tcctattgat gtccctgaaa
     2581 tcgaataaaa tttatttatt cctccatcat acaaggcttt aactactcct gcttgataag
     2641 ccccttttgc tcctccacct tctaaacata atcctaattt catagtctca tctccaaatt
     2701 gtttatctta tatttatatt tcaaaaaact tactaaatgt tttatatata ctatagtggt
     2761 cctcaacatt tcctaattct cttatagaat gcattgctaa aattggactt cccacatcca
     2821 cagatggtat atctatatga gtagaagata ttggacctat agtacttcct cctctttcat
     2881 ctgacctatt aacaaattct tgatactcaa cattagcttc tctacatata tttttataaa
     2941 tagctataga atatccatca ctagtatacg cctgactagc atttatcttt ataaccggac
     3001 cttttcccat tattggttta ttagttgggt catgcttttc tggaatgttt ggatgaatag
     3061 catgagctaa atctgatgat atcataaaag atgaataaat agactcaaag aatccctctc
     3121 tatccttacc cattgatata caaattctct ccaatatatt taacaacatg tttgaatctg
     3181 caccttgttt agtagagcta ccaacttctt cattgtcaaa tacagccatt acatttacac
     3241 catgttgacc tttagtatta acaagagcat tcaaactagc atgtaccatt gcaagattat
     3301 cttgtctccc aatagatata aattcatcat tagcccctat taaacttcct ttttcaaatt
     3361 catataaaaa taaatcaaaa tctataatat cgtccatatt tacatctaag ttagatgcta
     3421 tttgctttat aagaaaatta tctttttcta atgtatcatt taacatccca actaaaggta
     3481 acatatcttt ttgcttatta tatgaatgac catcatttat acttctattt aaatgtattg
     3541 ctagatttgg tattatacaa attggctttt taaagtctat aagcctttca tttggtttta
     3601 atatactatc accttttaaa actactctac cagctatccc aagaggtcta tccaaccatg
     3661 tacttaatat tgctcctcca tagcattctg tatttaactt caaataagat ttttcagctt
     3721 ctatttctgc atttggttta atactaaatg taggagaatc tgaatgagag cctattattc
     3781 taaatccatc tctttctata tcttctgaat ttactacaaa agctactata gctgataaat
     3841 tcttagtaac ataatacttt ccaccaactc ttagattcca tctttgattc aaaactaatt
     3901 cttcaaatcc atttttatct aagatttcct tagtactctt gactgcatga aaagacgacg
     3961 gactatcata tatgaagtct attaagtttt tagcaaagtt tatactatcc attcctcatt
     4021 tacctccatt ataaaatatt tagtgttgta tattctttat ttattttttt aattccctgt
     4081 tggtcaaaag ctatagtaac atctgtacca attatagaaa ccactgtccc aaccccaaat
     4141 ttaggatgat gtaccttaga accaagtttt atatcatctg gattagtttc tttattagaa
     4201 tcttttattg tagcattaac tttatctgca actttagatt tgcttatagt actcatatac
     4261 tttttagtat atttatctaa catattataa cttgctttag aatagcttag ttcttttttt
     4321 actttgtaca atctttctat acattcttct ggcagttctt ccataaatct tgaagctatt
     4381 gcaacatttg ttttaccata taatgttctc ttctctgtca atgacatata tagctcttct
     4441 ttagctctag ttataccaac ataacaaagt cttctctctt cttctatttg tgaatcactc
     4501 atagatttta tagctcttga tataggaaat aacccttctt ccatacctgt taaaaacaca
     4561 acagggaact ctaaaccttt agatgtatga attgtcataa gcgaaaccct atcattgtct
     4621 tcttcatcat ttgattcaga tgtaagtgct atacttgtta ggaatgtctc taagtcttta
     4681 ttttcataag tatcatcatt actactttca aactccaaag ctatagaaat aaattctctc
     4741 aaattatcaa ttctgtcttg agcttcttca cctttgcctg ttaaatcttt ttcattttta
     4801 tttcttatct ctacaagctc gtccatatat cctgtagtgt ccaagacttt ttctataagt
     4861 ttgctaacag gataaacttc ttttatagtt ctaagagtcc ctataatatc aacaaatcca
     4921 cttatacttg cccttgcctt agtagatata tctgaatttg tttctatatc aattaatact
     4981 gagtatatac tttcctgttt taagttagct ctatcttcaa ttttttctat ggttctaagc
     5041 cctatacctc ttctaggaac atttataatc ctttttatag atatatcatc ttgtggattt
     5101 tgaataactc ttaaatacgc caacaaatcc tttatttctt ttctctcata gaattttgta
     5161 ccaccatata tattgtatgg aatttgactt ctatttaaag cgtcctctac aggtcttgcc
     5221 tgtgcatttg ctctataaag tactgcaaaa tccttataag gtctattttc ttttctagct
     5281 atttgtgcaa ttgaatcagc aatgaaatca gcctcttcta tttcactacc agttaattgt
     5341 atctttataa gttctccttc ttttttttca ctccaaagct tttttctttt tctttctata
     5401 ttattagata taactttatt agctgcatct aatatcactt gtgtagacct ataattttgt
     5461 tccaacttta caacatgtac attgtcataa tctttctcaa attcaagtat gtttcttata
     5521 tctgcacctc tccatccata aatactttgg tcatcatctc caacaacaca aatattttga
     5581 tgttctcttg ctaataattt tatcaattca tattgagctt tacttgtatc ttggtactca
     5641 tctaccatta tgtatctaaa tctacttctg taatatgcta acacttcatc attagccttg
     5701 aaaagttcta cagttttaag tattaaatca tcaaagtcaa gtgcactatt tctttttaaa
     5761 cggtcttgat atagcgcata aatatctgca atcttaacca ttctattatc tgccatattg
     5821 atatctttaa actgctttgg agtataaagt ttatcttttg ctcctgaaat tgcacttata
     5881 actgcttttg gttcaaacac tttatcactt aaatttaatt cttttagaca gtctttaacc
     5941 aatgtaactt ggtctgctga atcataaatt acaaaacttc tattgtaacc aatcttattt
     6001 atatcttttc ttagtatacg aacacagcaa gaatggaatg tacttatcca catatcctta
     6061 gtttcaggac ctatattttg ttcaactctc tctctcattt catttgcagc tttgtttgta
     6121 aatgttatag ctaatatatt tggtgcttgt acacctttat cttctataag atatgctatt
     6181 cttgttgtta ataccttagt tttacctgaa ccagcaccag ccagtataag tactggacct
     6241 tcagtctttt ctactgcttc tctttgagca ggatttaatg tatctaaatt catatttctc
     6301 ctcctgttaa cagccataaa tatattttaa tctaaaatat gaattacttc aaattataat
     6361 tatgtattat attaatagat tatttccaat atattacaat taaataacat ttttccatat
     6421 aatttatttc attgtttaat aaaaaaaata accttatgat ttggggaatc ataaggcacc
     6481 tttaaggggt ctaggttaag ggttattata tataaatcta tttttttaaa ataggtttag
     6541 ggcttaatta tttatttgta ttaagttctc tttccttcca atacttatac aaatcttctt
     6601 ctttcttaaa taagggtaaa ttcatatttc tatgtacttt tactaaccat ggggattcta
     6661 ggccagcttg tataatatta ttttcattta taaacacatt ttctgctttt ccttcatcaa
     6721 tcaaaatccc cttatccaat acatatatgt aatcacatat ttcatacatt aaattcatat
     6781 catgactgga tattactatt tttatattat ttttatttaa tccctttatt atatctacaa
     6841 tagacctagt acttactggg tctaaaccag ctgtaggttc atcaagtaat acaatttcat
     6901 tttccattgc tataactgat gctattgcca ctcttttttt ctgtccatag ctaagaaaat
     6961 gtactggcct gtctataaaa tctattccat taacagctac tagagctttg tttattctct
     7021 ctttaattgt tttttcatcc ataccaatgt ttctcattgc aaaggctata tcatcatata
     7081 cttttgaata aaaaatttgt ttttctgggt cttggaacac aatacctaca ttttttctaa
     7141 ggttgtataa acttctctta tcatatttta acttttcttc tttaaaaaga atttctccag
     7201 atgtaggctt taatataccc attaaattca taaataatgt tgattttcct gaaccatttg
     7261 aacctattat acctataaca tttccctttg aaaaatccat attaatgttt aatagtgcat
     7321 tggtattttt ttcatattga tacgttaaat tatttatttt aaacatcatt atcccctact
     7381 atgtgaaatt taccatcata caattttatg tctaatgata tacacatatc atcatacctt
     7441 gtcataagtc ttttgtacag catacttcca agaataccta aggatttata tgaagttttt
     7501 aaatttatat atccaaatct tagctcttgt gacttgtata tttctgaaaa ttcttctaaa
     7561 aatatgaata taaacctata tattaacatt gataactcga caaaagtgtc aggtaaatga
     7621 agttttttaa aaaagaatat taattgatta aaaggtgttg taagtataca aaaatacaca
     7681 caagtcaaac aagacatcgc tctaaataac acatgaatag acatgtcaat agacgccttt
     7741 gatattccta cattaaaact aaaaaattca aaactatata ataaatctgc tttattaaaa
     7801 gatatattta caagagttat tcctatacta agaaataaaa agtacattgg tattctaagt
     7861 aattttaaat aattttttaa atctattcca gccacacaaa caaccaaaat actcattaaa
     7921 atcataattc cacttaaaat aaatatattt tgtattacca tagaagcaat cagaaaaatt
     7981 actcctatgg ctactttttt gtttggattt actttactca atctatttgt atatgcatat
     8041 ttatcaatta taagcatgat taacttctct ttcctttttg aagacctaat atgtatccta
     8101 ttacaccagc ccctaaagct gcttgtgcag agaataataa actttctatt tctccacttg
     8161 gtggctcata tggactgcta aaccatggtt tgtaatttgg atttatctta gtaatttcac
     8221 tttcagcttg accatctgct cctccatatt cagcacctga gttgacaagt aatgggaata
     8281 taataagagc tactactaat aaaagtaata atatgttagt ttttgtttta gcactcatta
     8341 gctttaactc ctttatcatt attttctagt atgctttttt ctccgttttc tgtaattaaa
     8401 ttatatacaa ttacagtaag tataccttct gctattgcta ttggtatttg agtcataaag
     8461 aaaattccta aaaatttaat tgctgaagcc attaccccac ctgatgggtc tgggaaagcc
     8521 agtgctaatt gtattgaagt tattgtatat gtggctaagt ctcctattgc tgctgcaaga
     8581 aatactggaa tagcattatt tccatctttt ttctttaaag ccttaaatat taggaatgat
     8641 acgattggcc ctattatcgc cattgaaaaa gcattagctc ctaaagtagt tattcctcca
     8701 tgtgctaata acaatgcttg gaatattaaa actatagttc caagaacaaa cattacgctt
     8761 ggtccaaaca ttattgctcc aagacctaca ccagtaggat gtgaacaact tcctgttact
     8821 gaaggtattt ttagtgctga taatacaaac acaaatgctc cacataaagc taataatact
     8881 ttctttttag ggtcttgctt tactatttta cctattgatt ttaatccgaa taagaaaaat
     8941 ggtataaata taactcccca tgctatagac cattttactg gtaagtaacc ttccattata
     9001 tgcattgcat ttgatgtaac tggagttaaa atgattaaca taagtgcagc tataacccct
     9061 aatttaatat tctgtttcat cttagtatcc ctctctccct ttctaataat taaaacataa
     9121 taatacatgt ctgatttatt taataaaata aaaaagccta actcgatggt taggcttcta
     9181 attttccaca atctaaatac aaacacataa aacaaacata tctgtataat tattataaga
     9241 aactttctcc atccccgaag aaattacttt aatattttag gcaggtctcc tgacttagct
     9301 tcatcctact cctcttcctt cccatgagat ataaaaaata tcatcatagt ggctaacaaa
     9361 agtttcgtct gcatcacagt agcgggggct gtaaaggaat ttaacctttt tccctattaa
     9421 tcttgcttaa agaacctata atattatata tttaattttt aaattcttct taaattattt
     9481 tctatataaa tcattgtata ccttttctgt gaaaatttct acatttttta taaattttat
     9541 tcatttttat atttttatgt atataaattc ttttttgtaa gtttattaat ttctaattat
     9601 cttctttaaa tacattgaaa ctacatcaga aaatctagtt atatctcttg aatatataaa
     9661 atcatttcca tatattaatc tttcagcttc aagttctgat tcttttcctg taaatactcc
     9721 taatactaat atattttgct ttctagcttt tctcacttca ttggctgtat ctctcaaacc
     9781 aactataccc ctataagcct tttctcctct taatgttctc tcactacttt ttcctatctt
     9841 tacatcattt ggtcttccat cactgagaac tatcaggatt ttattttctt catctctatt
     9901 tattagacca ctacatatag attttattgc caaaccatct ctattattac cagcacaaaa
     9961 atattcaaat atattttcac tattttttat actatcatca taatctttaa atctttttaa
    10021 tattgtatag tctaaaaaac tagaaaatcc catcactcta tttggtatgc caacttctgt
    10081 tagagcattt gcaattatgt aagcttgaat tgccacattt ccctgatttc tactttgaga
    10141 gccacttgca tccaataata tatcaataac gtatttccct ttttcatttt ctatatcttt
    10201 ataaaatatt ttattattat tacttctacc aactctccaa gctctattgg ctaatatagt
    10261 accacaatca gaatatactc tacttttagc attttcttct attaaaattc ttgatagact
    10321 ttcttttaat ctctttattt gctgtctata cattctagca tgttctctaa attttcctaa
    10381 attattttct ttttgtcttg ttacatattt tagttgaaat acattattac actcacttct
    10441 aagaactcca tctgtaaagt gtattctaca accttcatga acatttctac aattttgtgt
    10501 ctcaattttt ttaatttcac ctttactcaa ataagttttt ccataataat gttctatttt
    10561 tgaatatatc ttatttgcag tgtcttcatc aacatatata actcggtctg ctgaattgct
    10621 acatttagaa tcatcaaaat cccctacacc ttctacaagc atggatgaag atattgaatc
    10681 tatatcactt tcaataatat tttcttcttc atcactataa agttcttcat acatgaaatc
    10741 agcaaatgta tcaaaattta cttctacact ttctacatta ttttcatcaa taagactatt
    10801 ttcttctcca tttaatatgt attcaaaata agttaaatat ataacatcta atgcttttaa
    10861 aatctccata atatcttgat tggtatctat atttcttata tcattaacta ttcttctagt
    10921 catactatct aatgctgggt gcttgtccat actataaagt acaaatgtgt atttaatttt
    10981 atccataata ttatcattgt gtattttggt aaaacgtgaa acaatatctt tataagcatt
    11041 tcttcttatg tcttctatcc ctggcctatc tttaatgacc ttttcttcaa ctattgtatt
    11101 taatataact tgaattagac ccagtataat atctttgttg tatccttttc ttattctatt
    11161 tgtaagatat tttttaacta tatcccaatc tacatacttt cttctagcac ctgcaattat
    11221 tgcaaaatat agacctattt cttttgaaga gtaatctttt tctgatatat ctatactttc
    11281 attgtaatca ccagctattg tccatgataa gttattagct ctattttcaa attcataatc
    11341 atcatatatc catttcataa tctcacctat attaaatatg acttattgga aacacatcta
    11401 tactctccca tttattaggt attctagttt taattacatc tccaaccatt tctttctcat
    11461 atacatcaaa agtctttcct gtaagtccca tattaattgc aagagttggt tttaatcctc
    11521 ttcttatagt cttaagagat gccataagac cacgtaaatc aatagcttta ctagatatct
    11581 ctccattttg agacttcaat tgtaaatcta aaaatattcc tgcaaagtgt attagttttt
    11641 cttcatcagc atctgaaaat tcatttttta aaatcatcat taacttatct tcttctatag
    11701 gaggaatatc tattaccata aatctagata ccagtgcttc attaagttct tttgttcctg
    11761 catattcata attcatagtc ccaataaatc ttgttgctgg atgtagattg actctctcat
    11821 acccaggtac atcaattatt cttctatagt ctaaagctga atgtaccaca actatagcat
    11881 cattttttgc catattaatt tcatcaaaca ccccaaaacc tccattaata gcacactcat
    11941 aaactgagcc tcttctaagt ttaacttcat tgtctataaa tgtatctgta cctataagtg
    12001 ttgaactgtc tgtatttata tgaaatgatg tattccactg aggtctatta aatatttccc
    12061 ctagattatc agcaagtaag ttttttcccg ttgcctttgg tcccgataat aatatatttt
    12121 cttcttctaa aatagctgct atacacatag acaagatatc tttaccataa aaataagttt
    12181 tagactttgt tactctgtat tctaaatctt tttctaatcc ataataattt ctaaaataca
    12241 gtacatcttc aataagtttt tcatctaccc cttgcaccct tagattatct attatatcca
    12301 tatttttacc ccttttatat aaatagtatt tgtttcattt cttatcacca ttttagcata
    12361 aaaggatata agctaaaatt gattttttaa tctcccccat tttaagtaaa accatgcacc
    12421 attttatcac tacaaaatta agagtactac ttactgatat ttcttgattt tattcgtcta
    12481 tacgtatata atatatactg ataaattatg aggaaaggat gattgaaata tggaatatat
    12541 gtcttgccca gaagtagcaa aaaaatgggg tatttctgaa agaagagtac aaaaactatg
    12601 tgaagaaagt cgcataccag gagtttcaaa actcgggtat atgtggctga taccaaagaa
    12661 cgcagaaaag cctgttgatg gtagaacaaa aagaagaaag gaagtacaat atgaatagcg
    12721 ttttgattat agatgatgac aaagaacttt gtgctcttat gaaaaaatgt gttgagcaag
    12781 aaaatttatc tgctattact gcacatggtg gtgcagaagg tctacattta gtcgataaaa
    12841 atagacacac actctctctt gtaattttgg acataatgat gccagatata gacggttttc
    12901 aagttctgaa aaaaattaga gaaacaagta atattccagt aattatgctt actgctaaaa
    12961 atgacgagga tgataaagtt tccggactac gtttaggtgc tgacgattac ctaacaaaac
    13021 cgttcagcat aaacgaactt atggctcgtg tcaattctct tattcgtcgg tatactatgc
    13081 taaaccctgc ttttataaca gacacagatt tcataataat aaatggcatg attattgaca
    13141 agacaaaccg aattgtttct gtcaataata ttcctgttca acttacaagc aaagaatttg
    13201 atttacttgc ttttctggct tctaataagg gacgggtgtt taccaaaaaa cagatttata
    13261 cacaagtatg ggaagaagaa tatgcttttg acgatagtaa catcatgtct ttcatcagta
    13321 aattgagaaa aaagattgaa ccagacccca accatccatt ttatattttg acagttcgtg
    13381 gtgtcggtta tcgttttaat aaggaggctt aacatgaata caagtgtcta tctgcttttg
    13441 atattggctc ttagcctgat tattatagcg taccttgttt ctgtcctgct acgtgtccga
    13501 atacaactta cacttataaa agatgcttta gaggatataa aaaatggaaa ccttaatcga
    13561 cgtattttaa cagatgaaaa cgacattaca aaacaaattt gctatgatat taacgaaata
    13621 gcaatcaata gccaatttca acttattcag caaaaacaat cagaacaagc ctacaaacag
    13681 ctaatgacaa gtctctccca tgatgtaaaa actccacttg cttctttggt cggttatttg
    13741 gaagcagtag aaagtaaaat tgttgtagga gaggaaaaag acgagtatat ccatgttgcg
    13801 tctaataagg ctcattactt aaagaatttt gtagaaaatc tatttgaatg ggtaaaattg
    13861 gattctaagg aacaagtttt tcattttgat atttttgact tgaatgaatt atcccgtaat
    13921 attatatctg attggatacc tgttttagaa agcagtcatt ttgaatatga atttgatata
    13981 ccagaaatag agtacttctt acgtatagac gcaaatgcat atacccgtat cattaataac
    14041 ctattacaaa atattattac ccatagtagt ggaaacaaaa tgacattgag aatttttgaa
    14101 aacaaagagc aagctcaaat tataataaca gataatggga aaggtatatc ttcagacaat
    14161 ctcccacata tttttgaaag gttgtaccaa tgcgaccatt cacgagcttc aaagggaaat
    14221 ggtttaggct tggcgattgc aaaggaactt attaacgctc ataagggaaa tattaccgcc
    14281 aacagcactc ccggtatggg aacagaattt acaatattgc ttcctaaagc cctgtaaaag
    14341 tacgaggctt tcttactcta aaacaagata aaagcaagat tatggcaagg ttttggcaag
    14401 gttcatgttt tataattcta attgtagttg attttgacgt tgtatcaact atcttttgta
    14461 gaaacaaatt tattaaaagt gaggaaatta tatatgaatg attttgtgat tgaaacaaag
    14521 caacttacaa aaatttatgg gaatcaaaca gtagttgaca aagtcaatct ccatgtaaaa
    14581 aaaggccgaa tatatggtct gttaggacgc aacggagctg ggaaaaccac aattatgaaa
    14641 atgattttag gattgacttc aatcacgtat ggcgaggtag atgtatttgg agagaatatt
    14701 aagggacgtg aaaaacaagt atatccccgt atcggtgcaa ttatcgaaac gccaggattt
    14761 tatcctaatc tgacaggaac ggagaacttg gagatttttg caaaactgcg tggtacagcc
    14821 gcccctaatt ctgtaaaaag agcattggaa attgtaggct taccttataa aaataaaaag
    14881 ctgtttagta aatattcact tggcatgaaa cagcgacttg gtattgccaa cgctatcctg
    14941 catgacccag aactgttagt tttagatgag ccaaccaatg gtcttgaccc tattggtatt
    15001 gcggagatga gaaagtttat tagggacttg agcgttgagc atggaaagac aattcttatt
    15061 tccagtcata ttctttcaga aatctcattg ttggctgatg atattggaat tatcgaccac
    15121 ggtgttcttt tggaagaaag tagtatgagt gaactagaaa agaaaaacag taaatatatc
    15181 ctgctacaag tttcagatat tccgaagaca tcacttattt tagagcgtca atttaacacg
    15241 aaggattatt ccgttcaaga tgactacacg ttacaccttt ataacactaa tctggatatg
    15301 ggtgaaatca ataaagcact tgtaatgcag aatgtaactg ttattagttc tcaactttgt
    15361 aatgatactt tagaggacta ctttaaaaaa atcacaggag gagagggcat tgcttaaact
    15421 tattcaaaca gaatttctta aactgcgtcg taggaaactt atttggctga tgttgttgtc
    15481 tgctctcatt atgccgtttt tcgcactact atacttcaat tattttggta aaacaggtgt
    15541 tgagccaata aagttttata aatggtctgc atttggttat acactttgga ttattttgcc
    15601 tgttgttttg ggtatatttt gcaccatgct tatacacgaa gaaaaccagt atgatatgct
    15661 caaacagctt tggattgtac ctattagtaa aatgggatac ttttttagta aatttttcgt
    15721 tgttttgatt tactctattt gttttatgct gattacagcc gttgcttctg tgttatttag
    15781 tgtactttct ggatatgtcg tatttagctg ggcaagcatt ttatatttgt tgaaaaaatg
    15841 tttagaaatt ggtgtaatca ctgcttttgt aatgttgccg attttggcaa tcgctacatc
    15901 tcaaaaagga tacattctcc caatttgtat cacattggta tatgcctttt ccggttttgt
    15961 tataatgaca ataaatatgt atttacaccc attatccagt atgggagtta ttatcatgag
    16021 aaataaagac attccaggtc ttatattttc acaggaaatt aatgtcccat tagcatttct
    16081 ttgtatttgt atttggagta ttgtatcagt attgtttgca aatattgcac taggaagaag
    16141 aaagtgaggt gtagataatg tggaaattac tttgggctga atgtcaaaaa attcgtcgtt
    16201 caaaaattgt ttggattaca gtttttgcat ccattatgat agcagtcata gtttttgcag
    16261 gggggcagga tgtatataat gacccagatt tacattatgg cttaaagagc gtttatgacg
    16321 gttcacggta tatagacaat gcaggttggt atatggacgc agtacaacct tggtcaactt
    16381 tttttgttct tcctgctgtc attgccctat taggaagcta tattatttgt cgtgaagaag
    16441 aggaggacac tattaaatcc ctgcgtctta ttcccataaa tgaaacaaat ttaaccatag
    16501 caaaaatgat tattactttt atattcagta tacttcttta tttgttactc tttactataa
    16561 catttttgac tgaatccgtt ttacattttt ccgatttatc gacaaaattg gttttaagtt
    16621 gcatgaaaga gtattttctt gatggcatag gtgtattctt tgcaatttct cccattattg
    16681 ccttggtatc gcgcatgaaa aaaggatatt ggcttgcatt agtattcaca gaagtttatt
    16741 ctattgctgg actatttgcg ggtatgtcaa atgtcttaca aacctttttt cctattgcgg
    16801 caatatttaa tatttctgga tactatataa ctactggaga aaaaattatg gggagtatca
    16861 tgagtttatt actttgtgcc tgcctttctg catttatact taaagggcta aaacacaatg
    16921 aaaaaaattg aaataggtat atcaaaatga aaaagataaa aaaactgatt attctaattg
    16981 tattcttgtt tctttttggc atgttacact gttatactga atggaaattc aacaataacc
    17041 cacctaaagg ggtaatagaa agaataaatg agtggactga taagattgga ctggattagt
    17101 aacttatgtt aattatagtg aatgtaatat tagcaagtta ttgtttcgta ttttaatact
    17161 ataactttaa atatttggtt ttaatcttcc aaacgaatat aaaaaaactg tcacagaggc
    17221 aacatatttt tgaatattta taaagtggta gttttgattt tcaaagctac cgccttttct
    17281 tctatataag caaacttatc ctcaacaaag tgtaaaacat ggtgcatttt aagaaaaaag
    17341 taccacagac acaagcaata aaagaaacgc cgagaaccta caaaaacgta gtgcttatgc
    17401 agatttacga cgccttctat tttctcaacc gtcttaatga ccttgtacaa aagaaatttt
    17461 tctaatattt tttataatct tatcttgtga tgttttttat gtataaatga cttaataaca
    17521 aatccaataa aaattatgga tattggtata attagaacga ggaatttata atcattataa
    17581 tgtgacatta ttcttaccca actctcagaa aaaatatatc ctatactgat taatgaagta
    17641 ttccatatgg ttattcccac gatagatgat attacaaaag ttataatatt ttgacctgct
    17701 atacctgcta taaaagatat gtatgttcta cataaaggga ttaatctaca tacacaaaca
    17761 gaaatagaag agtatttatt aaaataatct tgagatgcaa atattccttt ctttgccttt
    17821 ggacatatct ctattatttt atttatgata gatttacctc cccaatttcc cactgtataa
    17881 caaaatatcg aaccaagtat acctgcaatt atacttaaaa ttaaaattgt cagaaatcca
    17941 aaatgatttc ttgcagcaat tgctccacat aaaggtaaaa caacttcgct aggtaatgga
    18001 aaacaagcat actcaatcat aattaataca aatacagaga ttaatccata ttgtaaaata
    18061 aaactattga ttacagacac ttacttatct atctcctttc ttatttaaag gttttaaggg
    18121 tacatgttct aaggattctc accctatatt taaagaatca atctctttaa actattatat
    18181 gtatttacac aaagcattta taacatactt taaaaatagt accttaaaat aagaaactta
    18241 ataaataaaa aaagattacg tggctacgtc ctactctccc aggcag
//
LOCUS       DAMJVG010000234        16317 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.guided.088, whole genome shotgun sequence.
ACCESSION   DAMJVG010000234 DAMJVG010000000
VERSION     DAMJVG010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16317)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16317)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16317
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.guided.088"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            complement(120..812)
                     /locus_tag="PC512_003848"
     CDS             complement(120..812)
                     /locus_tag="PC512_003848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HDF2443492.1"
                     /translation="MKSLNATEKIIDYIKLNILNGTFKINSKLPSERKIADLFNISRI
                     PVRNAINILCKEGILRAVPYSSPIVEGFKKVDLFDDGEIYKNHNIQEFYVESLRARQL
                     IESEATKLAILNATSKELQKIKYTYLKSIEELDKVSHGLIEECYDADLQFHKEIILAS
                     HNPIFIKYYELIPKTVSSNQYFGFKYRNSLKDMISHHNKIMIAFDSKDSYLGYTSMYN
                     HLEDVIQLFQHD"
     gene            complement(838..2025)
                     /locus_tag="PC512_003849"
     CDS             complement(838..2025)
                     /locus_tag="PC512_003849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2443493.1"
                     /translation="MKKISNQKLLLLSIVTFFWFSQYVYIPFQNPYLSACNVSTNMIG
                     IIIGAYGISQCLLRLPVGVFADSINKHKIFILSGIFFAGLASLIRVFSPGGNGFLIAN
                     ILSGISSSTWISYMVHYTNFFSTEHQQKATSTIILVNNLGMLIGFVMSTLFYEKLGMT
                     ALCIMSVLSSVIGTILALNIKNHNSKKIPEKISIKKYLSICKDKRLVFFSFMALIQQG
                     IQMSTTMSFTTQILKNLGSSSTLIGLSSIFYMVCAVASSGFASTKFCTKYGPKFWIPL
                     VFILVSAYCFLVPTIKNINIIFVLQVLPGISTGILLSYLTSESMKNVPKHQKSTAMGF
                     FQAIYAIGMSVFPMIVGKISEYTSIQYGYFILAIIAILASILSYTYYKKVDLTLNYDI
                     IQS"
     gene            2361..4238
                     /locus_tag="PC512_003850"
     CDS             2361..4238
                     /locus_tag="PC512_003850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2443494.1"
                     /translation="MDYKNIAQEILLNVGGKENVNEVTHCMTRLRFKVKSASKVNKDK
                     LSKTEGVITVVESMGQIQVVIGNKVKKVYDEVIKIVPQSNNVGKKNESQEKQGIINSI
                     LSAVAGIFTPTIPAIAGVGMIKGILSVLAMYYMNKNGVDIKETQSYIILNAMADSIFY
                     FMPIILGYTAAKVFNANKIISMVLGATLCYPTFTALMAGEESVRFLGLAVTKATYTSS
                     VIPIIIAIWALSYVEKVLEKYIPEVIKIIMVPTLSLVVMLPATLFLFGPIGIYIGNVI
                     NFSYKYIYELSPALCGAFVGGLWCVLVIFGAHRALLPIGISDVAQTGRQNLLAFAGAA
                     NFSQAGAALGVFFKTKNQGLKTISMSATITALFGITEPAIYGANLRLKKPMVCAVICG
                     AFGGAIMGMGGAYGNAFANQGVLTIPVYAEAGALGFLSYLGGCAIAFFGSAISTYLVG
                     FEDLEESSNKENSSIKVETKDGVIDITSPVEGECIELSEVKDDVFASKAMGEGIAVLP
                     TKGVITAPTDCEVASLFPTLHAIGLKLDNGAEMLIHVGINTVELNGKYFTKHVNQGDL
                     VKKGDKLISFDIDKIKKVGYDVTTPVIVNNTFDFGQVVSCKSSYVSTNDNIISLVLAG
                     N"
     gene            4548..5954
                     /locus_tag="PC512_003851"
     CDS             4548..5954
                     /locus_tag="PC512_003851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDF2443495.1"
                     /translation="MNTGFPKDFLWGASSSAFQVEGAWDKDNKGKTVADYNSFKKSHL
                     QADTKVASDFYHNYEEDIELMKELGMKTYRFSISWARIIPDGEGEINQKGLDFYNKII
                     DKLIECDIEPFVTLYHFDLPFKLVEKYNGWESRETVYAFERFAKICFKHFGDRVKYWQ
                     PHNEQNLIVRVEERINIYDETDSWKIDKMRAQMDYNLCLAHALAVNACHEMIKESKIG
                     AAVSSSVTYPLTSKPEDIYAARMNDNFKVYYMLDMHHYGEYPGYYMKYLEKRNIVPHM
                     EDGDKEILKKAKMDFIAVNYYRTNCAEALPEDSQHPFGLREGTVDFSMYGLFKMSMNP
                     NLEASEYGAAIDPSGLRVALNEYWQRYHLPVIITENGLGAKDILEDGKIHDDYRIDYL
                     RSHINACKLAIEDGVEMIGYCPWSFTDLLSSSQGFNKRYGLVYINRTDHEILDLKRIK
                     KDSFYWYKEVIENNGIVK"
     gene            5982..6830
                     /locus_tag="PC512_003852"
     CDS             5982..6830
                     /locus_tag="PC512_003852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF2443496.1"
                     /translation="MYITKVLNNSLLLAKDDNDEEIILMGKGIGHNYKAGSELNEKDI
                     EKIFVLHDENIKKSIIQLATEIDAEYFGIAQMIIAYGIEKYNLKLMNHIYLALTDHIA
                     FAVRRFKEGIMIENHYLFEIKEFNPKEYDIGKYAITVFKEVLGLDLPEEEIGNIAGHF
                     INAQQDNPYSDRNKRSAKIVNAILQIVHYHFSIVYNKESFYYRRFVMHLKAFSQRFLA
                     NEPSREKIDFIYEQVQKNCKEEYECVKKVGAYMYKEYSRELPRQEELYLMIHIHKILG
                     ELCENS"
     gene            7332..8024
                     /locus_tag="PC512_003853"
     CDS             7332..8024
                     /locus_tag="PC512_003853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003020373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2443497.1"
                     /translation="MNKVLIIDDDKDLCILLKKSISIEQIEANYCHSGRDGLVELSKQ
                     DYQLVVLDVMMPGMDGFETMEQIRKYSSIPILMLTSKSDNYSKVHGLRAGADDYLTKP
                     FEITEFTARVLSLIRRYTRFNPKNEEPQQLSFKGLLIDLDQHTVTTNGEPMLLPPKEF
                     GVLLYCARHQGKILTKQQIYEAVWGEPYVYDDSNIMAIISRLRKKIELDPSSPIYLQT
                     IKGIGYQFNTEV"
     gene            8021..8956
                     /locus_tag="PC512_003854"
     CDS             8021..8956
                     /locus_tag="PC512_003854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2443498.1"
                     /translation="MKMDEQTIILFLLLLSIGLLFLSIFAFSKLGHIHKRLKDIEEIL
                     ADVQIGDENRKILIKPCDVMAPLVYQLNEIVYDYENKLLSLKKSDKASKQLMTSLSHD
                     VRTPLTTLIGYLDAVHSGIVIEQEREEYLEIARRRAYDLKDYIDVLFDWFRLNSDEFT
                     LSIESVEIAELSRNILKDWIPIFHEKKLNFEIDIPENRLMVNLDPDGYSRVVNNLVQN
                     VLAHSKARQIKITMSEDSRMVLLRVEDDGVGIARENLPHIFERLYKCDKGRSEKGSGL
                     GLSIVSQMVERMGGQVSVESEIGKYTVFTVSLPLI"
     gene            9104..10027
                     /locus_tag="PC512_003855"
     CDS             9104..10027
                     /locus_tag="PC512_003855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013273760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2443499.1"
                     /translation="MNNLIIETKNLTKQYGAQKSVSNLNIHVQKGRIYGLLGRNGAGK
                     TTTMKMLLGLTKPTTGEIKIFGQDIHNNEKKLLPRIGCLIESPGFYPNLTGTENLKIF
                     ARLRGIPKKNAVESALDVVGLPNNDKKLFSQYSLGMKQRLAIALAIMHDPQLLILDEP
                     INGLDPIGIAEVRTFIRDLCTERGKTILISSHILSEIALLADDIGIIDHGILLEEESL
                     AQLEEKNSKYIHFAVSDAAQAARLLETQLNLKNFKVADNYNIMLYDTDVSVAEINRAF
                     ILNNIEVSESHLCEDTLEDYFKKVTGGEGIA"
     gene            10011..10781
                     /locus_tag="PC512_003856"
     CDS             10011..10781
                     /locus_tag="PC512_003856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2443500.1"
                     /translation="MKELLDIISCEFSKLKRLKFILISILGACLFPIPATILIAKDNL
                     PFEQLFKLVVNFGYFLLLPIVLSIVASQLFFIERDNDVLKNLATVPVPKGKLALAKLA
                     VLLFISLFYSVAGLGATIIGGFIVGIVEGVAVKLGMSIAFGIMFFVTVLPVVVLIVYF
                     NRSYIFSIILSFVYAIFNFSISLNIINFEPNNPLLSVLPAPVIMRWWMAFWGDPTGEY
                     TVLRQPYLLSTPACVGILCLITIIAVLLICMIYKKQEN"
     gene            10791..11573
                     /locus_tag="PC512_003857"
     CDS             10791..11573
                     /locus_tag="PC512_003857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2443501.1"
                     /translation="MLDIITTEFQKIKRYNILWIGVVAVLFSALLAVFQVVSSHGSDP
                     LTYESFANGVIWNNFSLSFPFGITLIGGYLINREYTDQTLKNILTVPISLRKLLVGKL
                     IAVGGITVLLSLFSFLCTFILGLLFCNINISVILVVKSLVQILSVNLYCYVAVLPIIA
                     YFGRKQNAFLTGVGIAFVYGFCGVFVAGRNLTDFYPITAGLGLVGYNNGAGTVYQPLI
                     GAMTLIVILILTTILLVFTPNYDKVMTISKKKGIKHKKYSHK"
     gene            11950..12486
                     /locus_tag="PC512_003858"
     CDS             11950..12486
                     /locus_tag="PC512_003858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin family protein"
                     /protein_id="HDF2443502.1"
                     /translation="MNLKGTKTEKNLMAGFAGESEARNKYTYYASKARKEGYNQIAAI
                     FEETANNEKEHAKLWFKLLHDGMPSTEENLKDAAAGENYEWTDMYAKFAKEAREEGFD
                     KIAYLFEAVGKIEKEHEERYLKLLENLNEGKIFKRDEEVVWQCQNCGHVYVGTEAPEK
                     CPVCDHPKAYFNIKAENY"
     gene            12518..12907
                     /locus_tag="PC512_003859"
     CDS             12518..12907
                     /locus_tag="PC512_003859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HDF2443503.1"
                     /translation="MKFSKQRELILNEILNNPVHPTADYLYENLKKDNPNLSLGTVYR
                     NLAQLTEHGFIRKVSIPGYPDRFDGRIDNHYHIICEVCGEVYDLESEVLNNLQELISE
                     ETDIKITSYNISFKGICNNCKRCSQVG"
     gene            12944..13330
                     /locus_tag="PC512_003860"
     CDS             12944..13330
                     /locus_tag="PC512_003860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="desulfoferrodoxin"
                     /protein_id="HDF2443504.1"
                     /translation="MCSEQKFFICETCGNLVGMIQSGGVPIFCCGKPMKELVPNTTDA
                     AVEKHVPVIEVDGNNVTVKVSSTTHPMTKEHHIAWVYLMTEQGGQRKCLAVDGEPVVK
                     FALNDDDKVISAYAYCNLHGLWKAEL"
     gene            13457..14899
                     /locus_tag="PC512_003861"
     CDS             13457..14899
                     /locus_tag="PC512_003861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HDF2443505.1"
                     /translation="MSIYKCSVCGYIYDESKNDKTWDELSEDWECPVCTKGRSYFGKI
                     STVYYEEDEKIAEDIVEDESKLNTEKEGDLNYLSTYLRRDDEVEKHMDIIHEMAVTGK
                     SIIEPMRTKLPVISWDDILIMGAQLNPLPLNEHDEVNTTTIIGKKAKKPMIIENPVYI
                     SHMSFGALSKELKIALAKGAAQNKTAMCSGEGGILPEEKEASYKYIFEYVPNKYSVTE
                     ENLKNSDAIEIKIGQGTKPGMGGHLPGEKVTEEIAKVRNKPVGQDVISPSCFEEIQSK
                     EDLKKLVDELREVSEGRPIGVKISAGHIEKDMEFIAYAKPDFVTIDGRGGATGASPKL
                     LKDATSIPTIFALYRARKYIDTHGLDIDLVITGGLRISTDFAKAIAMGADAVAIASSA
                     LMAAACQQYRICGSGKCPVGVATQDEELRKRLHIENSANRVANFLNVSLEELKTFARI
                     SGHKDIHDLSVDDLYTVNSEISNYTNIQHV"
     gene            15196..16011
                     /locus_tag="PC512_003862"
     CDS             15196..16011
                     /locus_tag="PC512_003862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2443506.1"
                     /translation="MERLKIQVLVDNNTYIDRYFVGEPAVSYYIEIDGNRILFDSGYS
                     DVFISNAEKLNIDLGNLTHVVFSHGHNDHTRGIQFLENRYDLSTVELISHPNCFIPRK
                     HGEKSIGAPFSAEEIKNIFMYNPKDKPFNLSKNCVFLGEIPSINDFEKRAKIGKCKIG
                     DLWEDDYVLDDSAIVCKTDKGIFIVTGCSHSGICNIVEYAKKVCGDDRVIGILGGFHL
                     FELNNRLDSTIQYLDKEEIRMLYPCHCVSFKVKAKMNEILNINEVGVGLTISI"
BASE COUNT         5910 a         2012 c         2983 g         5412 t
ORIGIN      
        1 ttgttgaaat gatgaaaata tatttgattt catacaaaaa agagtacctc ataactaaaa
       61 agttcacttt gagacactcc atttttatat gttagttgca tttaaggtaa aatagaagtt
      121 taatcatgtt gaaataactg aattacatct tctaaatgat tgtacattga tgtataacct
      181 aagtaagagt ctttactatc aaatgcaatc attatcttgt tatggtggct aatcatatcc
      241 ttgagagaat ttctatattt aaaaccaaag tattggttag aagaaactgt tttaggtatt
      301 aactcataat attttataaa aattggatta tgagaagcta aaattatctc tttgtgaaat
      361 tgcaagtcag catcataaca ttcttctatc aaaccgtgag aaaccttatc caattcttct
      421 attgacttta ggtaagtata ttttattttt tgaagttctt tagatgtagc atttaaaatt
      481 gctagtttag tagcttcact ttcgataagt tgtcttgctc ttaaagattc tacataaaat
      541 tcttgtatgt tatgattttt atagatttca ccatcatcaa ataggtcaac ttttttaaat
      601 ccttcaacta taggacttga ataaggcaca gctctaagta ttccttcctt acagagtata
      661 tttatggcat ttcttacagg tattctactt atgttaaata ggtcagcaat ctttctctca
      721 cttggtaatt tactattaat tttaaaagtt ccatttagaa tgtttaattt aatataatca
      781 ataatttttt cagtggcatt taagcttttc ataaaaactc ctaaacatat aattttttta
      841 tgattgtatt atatcatagt taagagttaa atctactttt ttataatatg tataagacag
      901 gatagaggcc aaaatagcta taatagccaa gataaagtat ccatattgta ttgaagtata
      961 ttccgatatt ttaccaacta tcattggaaa tacagacatt cctatagcat aaattgcttg
     1021 aaaaaaaccc attgcagtag atttctgatg ttttggtaca tttttcatag actcgctagt
     1081 aaggtaagaa aggagtatac ctgtagatat acctggtagt acttgtagta caaatattat
     1141 attaatattt tttattgttg gaactaaaaa gcaataggct gaaactaaaa taaaaactaa
     1201 aggaatccaa aattttggcc catacttagt acaaaattta gtagaagcaa agccagaaga
     1261 agcaacagca cacaccatgt aaaatataga agatagacct atgagggtag aactagaacc
     1321 taagttttta agaatttgag tagtaaatga cattgttgta gacatttgaa taccctgttg
     1381 aattaatgcc ataaaggaaa aaaatacaag tcttttatcc ttgcagatag ataaatattt
     1441 tttaattgat attttttcag gtattttttt tgaattatga ttttttatat ttaaggctag
     1501 aatcgttcca ataactgaag acaatacact catgatacat aaggctgtca ttcctaattt
     1561 ttcataaaat aaagtactca taacaaatcc aatcaacatt cctagattgt ttactaatat
     1621 tattgtactt gtagcttttt gttgatgttc tgtagaaaaa aagttggtat agtgaaccat
     1681 gtaagaaatc caagttgatg atgatattcc agataaaatg ttagctataa gaaaaccatt
     1741 gcctccagga gaaaagactc ttataagaga tgctaaacca gcaaagaaaa ttccagacag
     1801 tataaatatt ttatgtttat ttatggaatc agcaaatact ccaacaggaa gccttaataa
     1861 acattgtgag attccatatg cacctattat tataccaatc atatttgtag atacattaca
     1921 tgcacttaaa tatggatttt ggaaaggtat atatacatat tgtgaaaacc agaaaaatgt
     1981 aacaatagaa agtaaaagta atttttgatt agatattttt ttcatattat cctccgtatg
     2041 gtatttttat aatgcaaata atataccatt tggatttttt aatcaagtac tttctctatt
     2101 aaaaaaaatt taaatatata attattattt acaaaaaaat tatactttat agttgaatta
     2161 agaaaacgct tatgatacta taaagttaac aaatttgaat atataacagt agacgtgtta
     2221 ctggtaatgc aggcaagatc gaatcaattt ttatagatta tctatagagt actatgggta
     2281 taatctattt atttggttcg atttttttgt ttaattggcc ataaaacaaa aagcctatag
     2341 ttgaaaatgg aggatttttt atggattata aaaatatagc tcaagaaatt ctactaaatg
     2401 taggaggaaa agagaatgta aatgaagtga ctcattgtat gacaagactt agatttaaag
     2461 tcaaaagcgc ttctaaagtg aataaggata aattatctaa aactgaagga gtaataactg
     2521 ttgttgagag tatgggtcaa atacaagttg taattggaaa taaagtaaaa aaagtatatg
     2581 atgaggttat aaaaattgta cctcaatcaa ataacgtagg taaaaagaat gaaagtcaag
     2641 aaaagcaagg tataattaat tctatattat cagcagtagc tggtatattt acacctacaa
     2701 tacctgctat agcaggggtt ggtatgatta aaggtatttt atcagttctt gctatgtatt
     2761 atatgaataa aaatggagta gatataaaag aaacgcaaag ctatattatc ttaaatgcca
     2821 tggctgattc tatattctat tttatgccta ttatactagg atatactgcg gctaaagtat
     2881 ttaatgcaaa taaaataata tctatggtat taggagctac actttgttat ccaactttta
     2941 ctgctttgat ggcaggtgaa gaatctgtta gatttttagg attggcagta acaaaagcta
     3001 cgtatacatc atctgttatt ccaataatta ttgctatatg ggctctttca tacgttgaaa
     3061 aagtattaga aaagtatata cctgaggtaa ttaaaataat aatggttcca actttatcat
     3121 tggtagtaat gttacctgca acattatttt tatttggacc aatcggaatt tatataggaa
     3181 atgtcataaa cttttcttat aagtatattt atgaattaag cccagcattg tgtggagcat
     3241 ttgtaggtgg gttatggtgt gtgttggtta tatttggtgc tcatagagca ttattaccaa
     3301 taggtataag tgatgttgct caaacaggaa gacagaattt attggcattt gcaggagctg
     3361 caaacttttc acaagcaggg gctgctctag gagtattctt taaaactaaa aatcaaggac
     3421 taaaaacaat ttctatgtct gcaactataa cagctttatt tggtataact gaacctgcaa
     3481 tatacggtgc caatcttaga ttaaaaaagc ctatggtatg tgccgtaata tgtggtgcat
     3541 ttggaggtgc gataatggga atgggtggag cttatggtaa tgcatttgca aaccaaggtg
     3601 ttttaactat acctgtatat gctgaagcag gtgcattagg tttcttaagt tatctaggtg
     3661 gttgtgctat agcatttttt ggttcagcta tttcaactta tctagttgga tttgaagatt
     3721 tggaagagtc ttctaataag gaaaattcat ctataaaagt agaaacgaag gatggtgtta
     3781 ttgatataac ttcacctgta gagggcgaat gtatagaatt gtcagaagta aaggatgatg
     3841 tatttgcttc aaaagctatg ggagaaggta tagctgtgtt acctacaaaa ggagtaataa
     3901 cagcccctac tgattgtgaa gtagcttctt tatttccaac attacatgca ataggattaa
     3961 aattagataa tggagcagaa atgttaatac atgttggaat caatacagta gagttaaatg
     4021 gtaaatactt taccaaacat gttaatcaag gagatttagt gaaaaaaggt gataaactta
     4081 tatcgtttga tatagataaa ataaaaaagg ttggttatga tgtaactacg ccagttatag
     4141 taaacaatac atttgatttt gggcaagtag tttcttgtaa atctagttat gtttcaacca
     4201 atgataatat aatttcatta gtattagctg gtaattaagt taatttgact agagataagt
     4261 aaattgattt aaaaggaaat aagtaaatca acaattaaat acatctaaaa gtaagtttat
     4321 tgcaatgaat tgttaaagaa aataattaat atggagtaaa tctattgcaa tgaagtaaca
     4381 aagaaaataa ttaatataga gtaagtttat tgtaatgaat tgttaaagaa aataattaat
     4441 atagggtaaa tctatttcaa tgaaataaca aagaaaagag ttaatataga gtgaacttat
     4501 tgcaatgaat caacaaagaa aataattaat aaaaaggaga aatatttatg aatacaggat
     4561 ttccaaaaga ctttttatgg ggagcatcat cttctgcatt tcaagtggaa ggagcttggg
     4621 ataaagacaa taaaggaaaa accgtagccg actataattc ttttaaaaag tctcatttac
     4681 aggcagatac taaagtcgca tcagactttt accataatta tgaagaagat attgaattaa
     4741 tgaaagaatt agggatgaaa acatatcgtt tttcaatttc atgggcaagg ataataccag
     4801 atggtgaagg agagataaac cagaaaggtt tagactttta taataagata atagacaaac
     4861 taatagagtg tgatattgag ccattcgtga ctttatacca ttttgacctt ccatttaaat
     4921 tagtagagaa atataatggt tgggaaagta gagaaactgt ctatgctttt gaaagatttg
     4981 ctaaaatatg ctttaagcat tttggagata gggtaaagta ttggcaacct cataatgaac
     5041 agaatttaat tgttagagtg gaggagagaa ttaatatata tgatgaaaca gattcatgga
     5101 agatagataa aatgcgtgct cagatggatt ataatctttg cttagcacat gcattagcag
     5161 tcaatgcatg tcatgagatg ataaaagaaa gtaaaattgg agcagcagta tcatcatctg
     5221 taacatatcc tcttacttct aagccagaag atatatatgc agctagaatg aatgataatt
     5281 ttaaagtgta ctatatgctt gatatgcatc attatggaga atatccaggg tattatatga
     5341 agtatcttga aaaaagaaat atagttcctc acatggaaga tggggataaa gagatactta
     5401 aaaaagctaa aatggatttt atagctgtaa attattatag gacaaattgt gcagaagctt
     5461 tacctgaaga ttcacaacat ccatttggat taagagaagg aactgttgat tttagtatgt
     5521 atggactatt taaaatgtca atgaatccta acttagaggc ttctgagtat ggagcagcaa
     5581 tagacccatc aggtcttaga gttgccttaa atgaatattg gcaaagatat cacttacctg
     5641 ttataataac agaaaatggt ctaggagcta aagatatatt agaagatgga aaaattcatg
     5701 atgactatcg tatagactat ttaagaagtc atataaatgc atgtaaacta gctattgaag
     5761 atggtgtaga gatgattgga tattgtccat ggtcatttac agacctttta agttcttctc
     5821 aaggttttaa taagcgttat ggacttgttt atataaatag aactgaccat gaaattttag
     5881 atttaaaaag aatcaagaaa gatagttttt actggtataa agaagttata gagaacaatg
     5941 gaatagtaaa ataaacataa atatatattg agggttttag tatgtacatt acaaaggtat
     6001 taaataattc gttgctactt gcaaaggatg ataatgatga agaaataata ttgatgggga
     6061 aaggcattgg ccataattat aaggccgggt ctgagttaaa tgaaaaagat atagaaaaga
     6121 tttttgttct tcatgatgaa aatataaaaa agagtattat acaattggca acagaaatag
     6181 atgcagaata ttttggtata gctcaaatga taattgcata tggaatagaa aaatataact
     6241 taaaacttat gaaccatata tatttggcct taactgacca cattgccttt gcagtgagac
     6301 gttttaaaga aggtataatg attgaaaatc actatttgtt cgaaatcaag gaatttaatc
     6361 caaaagagta tgatatagga aaatatgcta ttactgtttt taaggaggtt cttggtttag
     6421 acctaccaga agaagagatt ggtaatatag caggccattt tataaatgca caacaagata
     6481 atccttatag tgatagaaat aagagaagtg ctaaaattgt aaatgctatt ttgcaaatag
     6541 ttcattatca cttttctatt gtatataata aagagtcatt ttattatagg agatttgtaa
     6601 tgcatctaaa ggccttttca caaagatttc tggctaatga accatcaaga gaaaaaatag
     6661 attttatata tgagcaagtt caaaaaaatt gtaaggaaga gtatgaatgt gtgaaaaagg
     6721 taggagctta tatgtataag gaatactcca gagaattacc aagacaagag gagttatatt
     6781 tgatgattca tattcataag attttaggag aattatgcga aaatagttag aatatcttaa
     6841 tatgctagta atattataaa aaattaaaaa ttaactgcac tttaaatatg aataattgca
     6901 ttacttaagg gggttgtctt aaaattgatt tttttaatta aatttgaagc tcaactcctt
     6961 ttttaaacct ttatatcatt acaactttaa tgtttatacg cctgtacttc agatgtatat
     7021 ctacttttta catttctcaa catgcaaatc taccattctg tatatagtaa atgtattatc
     7081 atgtttgttt tattcaagca cacttataat acgcttgatt ttttcacaat gatgaaatat
     7141 actaatgggt gttataggta taagaatcgc attacacttg aagaagtaag tgataaatga
     7201 gatataaatc ctcatatgat aaactactat ttcattgagg aacatattct aagtgatgtc
     7261 aagatactac aatatgacta aattcctagt gataaaaaag tctacgaatg agtgtagaaa
     7321 ggggaactaa gatgaataaa gttttaatta tagatgatga taaagatctt tgtattttgt
     7381 taaaaaagag tatttcaatt gaacagattg aagcaaacta ttgccattct gggagagatg
     7441 gactggttga actttcaaaa caagattatc agttagtagt tctagatgtg atgatgccag
     7501 gtatggatgg ttttgaaact atggaacaaa tacgaaaata tagcagtatt cctatcttaa
     7561 tgctgacatc aaaaagtgat aattacagca aagtgcatgg attgcgagct ggtgcagatg
     7621 actatctaac caaaccattt gaaattacag aatttactgc tcgtgtactg tctttaatcc
     7681 gacgttacac ccgttttaat ccaaaaaatg aggagccaca gcaactttct ttcaaaggtt
     7741 tgttgattga ccttgaccag catacagtta ctaccaatgg cgaacctatg ttgcttccac
     7801 ccaaggaatt tggtgtactt ctttactgtg caaggcatca gggtaagatt ttgacaaaac
     7861 agcagattta tgaagccgtg tggggtgagc catatgtata tgatgacagc aatatcatgg
     7921 ctattatcag tcgcctaaga aaaaaaattg aactagaccc atcatctccc atctatttgc
     7981 aaacaataaa aggaattggg tatcaattca acacggaggt atgaaaatgg atgaacaaac
     8041 gataattctt ttcttactct tgctgtcgat tggtctactt tttctttcca tatttgcttt
     8101 ttccaagctt gggcatattc acaaacgctt aaaagatata gaggagatac tcgctgatgt
     8161 acaaattgga gacgaaaatc gtaaaatact aattaagcca tgtgatgtta tggctccatt
     8221 ggtttatcag cttaatgaga ttgtctacga ttatgaaaat aagttacttt ctctgaaaaa
     8281 gtcggataaa gctagcaaac aacttatgac aagtttatct catgatgttc gtacaccatt
     8341 aacaactctg attggttatc tggatgctgt acacagtggt atagttatcg aacaagagcg
     8401 ggaggaatac cttgaaatcg ctaggcgtag agcctacgac ctcaaggatt acattgatgt
     8461 tctttttgac tggtttcggt tgaactctga tgaatttacg ctgtcaatag aatctgtgga
     8521 aattgcagag ttgtcacgca atattttgaa agactggatt cctatattcc atgaaaagaa
     8581 actgaatttt gaaattgata ttccagaaaa tcgactaatg gtaaacctcg acccagatgg
     8641 atattcccgt gtggtcaata atctggttca aaatgttctt gctcacagta aggctcggca
     8701 aatcaagatt accatgagtg aggattccag aatggtatta ctccgtgttg aggatgatgg
     8761 tgttgggatt gccagagaaa atttaccaca tatttttgag cgactgtata agtgtgataa
     8821 aggacgttca gaaaaaggaa gtggtcttgg tctatctatt gtcagtcaaa tggtggagcg
     8881 aatgggtggt caggtttccg tagaaagtga gattggaaag tataccgtat ttacagtgag
     8941 cttaccatta atataaaatt gtttttcccc catgtgacat gtatacacag ggggattttt
     9001 tgtaagttat aaagttgcaa ggttaataca aggttgttgc aaggttaatg taagattgag
     9061 gtggtatgat aactttaata aacaaaggag gcttttatta tttatgaata atttaattat
     9121 tgaaacaaaa aatctcacta agcaatatgg tgctcaaaag agcgtttcta atttgaatat
     9181 tcacgttcag aaaggtcgca tttacggatt gctaggaaga aacggtgcgg gtaagacgac
     9241 aactatgaaa atgttattgg gcctaacaaa accaactact ggagaaatta aaatatttgg
     9301 tcaggacatt cacaataacg agaagaagct tcttcctcga attggatgtt tgattgaatc
     9361 accagggttt tatcctaatc tgacaggaac agaaaatctc aaaatctttg caaggcttag
     9421 aggaatacca aaaaaaaatg cagtagaatc agcactggat gtagtcggtt tgccaaacaa
     9481 tgacaaaaag ttattttctc aatactctct tggtatgaaa cagaggttgg cgattgctct
     9541 tgccattatg catgacccac aactgttgat tttggacgag cctatcaatg gacttgatcc
     9601 tattggtatt gcagaagtaa gaacgtttat tcgtgatctc tgcacagaac gaggtaaaac
     9661 tattttgatt tccagtcaca ttctttctga aattgccttg ttggcagatg acattggcat
     9721 tattgaccat ggtattttgt tggaggaaga aagtcttgcc caattagaag aaaaaaacag
     9781 taaatacata cattttgctg tatctgatgc agcacaggca gcaaggcttc tggaaaccca
     9841 acttaacctg aaaaatttca aagtagcaga taattacaat attatgctat atgatacaga
     9901 tgtttctgtt gcagaaataa atcgtgcttt cattctaaac aacattgagg tatcagaatc
     9961 tcatttatgc gaagatactc ttgaagatta cttcaagaaa gtaacagggg gtgaaggaat
    10021 tgcttgatat aatttcatgt gaattttcaa aactcaagcg gttaaaattt atactgattt
    10081 ctattttagg tgcttgctta tttccaattc ccgcaacaat tttgattgca aaggacaact
    10141 tgccctttga gcaattgttc aaattagttg tcaattttgg atatttcttg ctattaccaa
    10201 ttgtattaag tattgttgct agccaactat tttttataga aagagataat gatgtattaa
    10261 aaaatcttgc aacagtgcca gtgccaaaag gaaaactggc tctggcaaaa ttggctgtgt
    10321 tgctgtttat atcattgttc tactctgttg cagggttagg agctactatc attggaggtt
    10381 tcattgttgg aatagtagag ggggttgctg taaaattagg aatgagcatt gcttttggaa
    10441 ttatgttttt tgttactgta cttcctgttg tggtactcat tgtatatttc aatcgcagct
    10501 atattttttc tattatactt tcttttgtat atgctatttt caattttagt atatccttaa
    10561 atattatcaa ttttgaacca aataacccac tattaagcgt attacctgct cctgttataa
    10621 tgcgttggtg gatggcattt tggggagatc ccactggcga atacacggta cttagacagc
    10681 catatttgct ctcaactcct gcttgtgtag gtattttatg tttgataacc attatagcag
    10741 tcctgctgat ttgtatgata tacaaaaagc aggagaatta ggaggtatct atgcttgata
    10801 taattactac agaatttcaa aaaataaaaa gatataatat tctatggatt ggtgttgttg
    10861 ctgttctgtt ttcagcacta ttggcagttt ttcaggttgt aagttcacac ggcagtgacc
    10921 ctctaacgta tgagagcttt gcaaacggag ttatctggaa taatttcagt cttagttttc
    10981 catttgggat tacacttatt ggaggatatc ttattaaccg tgaatataca gaccaaacct
    11041 taaaaaacat cctaactgtt cctatttcat tacgcaaatt gctagtggga aaattaattg
    11101 cggttggagg aattactgta ttgttaagtc ttttcagctt cttatgcaca tttattttgg
    11161 ggttgttatt ttgcaatatc aatatatctg ttatactcgt tgtaaaatcc ttagttcaga
    11221 ttttgtctgt taatctgtat tgttatgttg ctgttttgcc gattattgct tattttggtc
    11281 gtaaacaaaa tgcatttctg acgggtgtag ggattgcatt tgtatacggt ttttgtggtg
    11341 tgtttgttgc tggaagaaat ctgacagact tttatccaat cacagcaggt cttggtctag
    11401 ttggatacaa caatggtgct ggtactgttt atcagccact tatcggtgct atgactttga
    11461 ttgtaattct aatcttgaca actattctac ttgtatttac acctaattat gataaagtta
    11521 tgaccatatc taagaaaaaa gggataaagc ataaaaagta ttctcataaa taacataaat
    11581 attgtttcta ttatttaagt tgctagacag tgaaaagaaa aaatctgtcg tacagtggct
    11641 atatgctcat gtattcaaga agctacagtt ttgatttttc ataactgtag cttctttttg
    11701 tatttattaa atcacgacta tcataatact tgcaataggt atagtaacaa gagagagtac
    11761 tgtcatatgt gttttatata ttacattaag tatattctaa aatatatgtt ttaaataata
    11821 tatttgaaaa taggaatatt taaataaaaa aaataatatt atatatagtt gacaaaaatt
    11881 ggcaaatgat atactatata aatatagaaa tagtaatcat tactattatt aaaaagggag
    11941 gaattaatta tgaacttaaa aggaactaaa acagaaaaga atttaatggc aggatttgca
    12001 ggagagtcag aagcaagaaa taaatataca tactacgctt caaaagcaag aaaagaaggt
    12061 tataatcaaa tagctgctat atttgaagaa actgctaaca atgaaaagga acatgctaaa
    12121 ttatggttta aacttttaca tgatggtatg ccttcaacag aggaaaattt aaaggatgca
    12181 gcagcaggtg aaaactatga atggactgat atgtatgcaa aatttgctaa agaagctaga
    12241 gaagaaggat ttgacaagat agcttattta tttgaagctg ttggaaaaat agagaaagag
    12301 catgaagaaa gatacttaaa gcttttagaa aacttaaatg aaggaaaaat atttaaaaga
    12361 gatgaagaag ttgtttggca atgtcaaaac tgtggtcatg tgtatgtagg tactgaagca
    12421 ccagaaaaat gcccagtatg tgaccatcca aaagcatatt ttaatataaa agctgaaaat
    12481 tattaaaaat tatcattatt aaaaaggaat gttaactatg aaattttcta aacaacgaga
    12541 actgatttta aatgaaatat taaataatcc ggttcatcct actgcggatt acctatatga
    12601 aaacttaaaa aaagataatc cgaatttaag cttaggaact gtgtatagaa atttagctca
    12661 gctaacggaa catggcttta taagaaaggt tagtattcca gggtatccag atagatttga
    12721 tggtcgaata gataatcact atcatatcat atgtgaagta tgtggagagg tatacgattt
    12781 agaatccgaa gttcttaata atttacaaga attaatatct gaggagacag acataaaaat
    12841 aacatcttat aacataagtt ttaaagggat ttgtaataat tgtaaaaggt gtagccaagt
    12901 aggttagttt tcaaattcta aaaataatta atgaggtgag tttatgtgta gtgaacaaaa
    12961 attttttata tgtgagactt gtggaaacct tgtaggaatg atacaaagtg gtggtgtacc
    13021 tattttctgt tgtggaaaac ctatgaagga acttgttcct aatacaacag atgcagcagt
    13081 tgaaaaacat gtacctgtaa ttgaagtgga tggaaataat gttactgtta aagtaagtag
    13141 cacaactcat ccaatgacta aagaacatca tatagcatgg gtgtatctta tgactgaaca
    13201 aggtggtcaa cgcaaatgtc tagcagtaga tggagaacct gtagttaaat ttgctttgaa
    13261 tgatgatgat aaagtgattt ctgcctatgc ttactgtaat ttacatggat tatggaaggc
    13321 tgaactgtaa tatttaaata aattgagtca aaaaggaggc tataaatgta ttttcataca
    13381 aatagcctcc tataaattta tataaattca agttttaatt ttgtttaatg tcaatataat
    13441 ataaggagaa aataatatgt caatttataa atgtagtgtt tgtggatata tttatgatga
    13501 atctaagaat gataaaacat gggatgaatt aagtgaagat tgggaatgcc ctgtatgtac
    13561 aaaaggtcgt agttattttg gaaagataag tactgtttac tatgaagaag atgaaaagat
    13621 agcagaagac atagttgaag atgaatctaa attaaatact gaaaaagagg gagatttaaa
    13681 ttacttaagt acatatttaa gaagagatga tgaagttgag aaacatatgg atataattca
    13741 cgaaatggct gttacaggaa aatctataat agaacctatg agaactaaac taccagtaat
    13801 ttcttgggat gatattttaa ttatgggtgc tcaattaaat ccattacctt taaatgagca
    13861 tgatgaagta aatacaacaa caataatagg aaaaaaagca aagaaaccta tgattataga
    13921 aaatccagtt tatatttccc acatgtcatt tggagctttg tctaaagaac taaaaatagc
    13981 tttagcaaag ggtgcagccc aaaataagac agctatgtgt agtggtgaag gaggtatatt
    14041 accagaagag aaggaagctt catacaagta tatttttgag tatgtaccaa ataaatatag
    14101 tgtaactgaa gaaaatctta aaaattctga tgctatagag ataaaaattg gtcaaggaac
    14161 aaaacctggt atgggaggtc atcttcctgg cgaaaaagta actgaagaaa tagcaaaagt
    14221 aagaaataag cctgtaggtc aagatgtaat aagtccatct tgttttgagg aaatacaatc
    14281 caaagaggat ttaaagaaac ttgtagatga acttagagaa gtttcagaag ggcgtccaat
    14341 aggtgttaaa atttcagcag gtcatattga aaaagatatg gaatttatag cttatgctaa
    14401 acctgatttt gtaactattg atggtcgtgg tggagctact ggagcaagtc caaagttgct
    14461 taaagatgca acttcaattc caacaatatt tgctctttat cgtgctagaa aatacataga
    14521 tacacatgga ttagatatag atttggttat aacaggtggg cttcgtatat ctactgattt
    14581 tgctaaggca attgctatgg gggctgatgc agttgctatt gcaagttctg ctcttatggc
    14641 agcggcgtgt caacaatatc gtatatgtgg ttctggtaag tgtcctgtag gagtagctac
    14701 tcaggatgag gaattgagaa aaagattaca tatagaaaat agtgctaata gagtggcaaa
    14761 ctttttaaat gtaagtttag aagaacttaa gacttttgct agaatttctg gtcataaaga
    14821 tatacatgat ttaagtgttg atgatttata tactgttaac tctgaaatat caaattatac
    14881 aaacatacag catgtataga ttgaagtttg aaactattag attttagaca gctataaaag
    14941 taaatgataa atatatttta taaaagagag tgtcttaaaa tgaacttttt agttcataag
    15001 tcactctttt ttgtatgaag ccaaatatat ttatcatttt agcaatgaaa aagaatctta
    15061 tctctttatt ttgagataga ctccttctat ttatgaaaat taaagatatt aaattgtaaa
    15121 atattctgtg atgtcgtact attaaactaa agattctgta ctttaaagta aataaaaatt
    15181 taaggagtga ttattatgga aagattgaag atacaagttt tagtcgacaa taatacttat
    15241 attgatagat actttgttgg agaaccagca gtaagctatt atattgagat tgatggaaat
    15301 aggattttgt ttgactcagg gtattcagat gtattcatat caaacgctga aaaattaaat
    15361 atagatttag gaaatttaac tcatgttgtt ttttctcatg ggcataatga ccatacaaga
    15421 ggtatccagt ttttagaaaa taggtatgat ttatctacag ttgaacttat ttcacatcct
    15481 aactgtttta tacctagaaa acatggagag aaaagcatag gagctccatt ttctgctgag
    15541 gaaattaaaa atatttttat gtataatcct aaggataagc catttaatct aagcaagaat
    15601 tgtgtgtttt taggtgaaat accttctata aatgattttg aaaaaagagc taaaattggt
    15661 aaatgtaaaa taggagattt gtgggaagat gattatgttt tagatgattc tgctatagtt
    15721 tgtaaaactg ataaaggtat ttttattgtt acaggatgtt ctcatagtgg aatttgtaat
    15781 atagtagagt atgctaaaaa ggtatgtgga gatgatagag ttattggtat actaggtggt
    15841 tttcatcttt ttgaattgaa taataggtta gatagtacaa tacaatattt ggataaagaa
    15901 gaaataagaa tgttgtaccc ttgtcactgt gtttctttta aggtaaaagc gaagatgaat
    15961 gaaatattga atataaatga agttggagta gggctgacca taagtatata gtatttgaaa
    16021 gtatataaga tttaagttga aggttaaaaa gatattttct atagaaaata tcttttttgt
    16081 tacgtttatt ttaagagaaa tcaatatact tttatatgaa atattgtaaa aaaatttatt
    16141 tttaatgaga atatattttc attaataaac aattttatta tgtattaata atgttagaat
    16201 aaatataaat aaatcaaagt tacttacatt acagtatatt ttttcacaaa atatattgat
    16261 ttattctttt aaagtttgat aattccaatg aatgtaataa aagaaggaat tttatac
//
LOCUS       DAMJVG010000235        15199 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.guided.093, whole genome shotgun sequence.
ACCESSION   DAMJVG010000235 DAMJVG010000000
VERSION     DAMJVG010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15199)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15199)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15199
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.guided.093"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            278..1231
                     /gene="blaCDD"
                     /locus_tag="PC512_003863"
     CDS             278..1231
                     /gene="blaCDD"
                     /locus_tag="PC512_003863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDD family class D beta-lactamase"
                     /protein_id="HDF2443507.1"
                     /translation="MKRKKNFIWIAILLVGVVMVMYYVGKKHNDINQKTDKNYIKSEL
                     NKSELNKSKIENNDKNKKEKINMVDYSDCFEGISGGAIFYNTKNKEYNIYNKELIETR
                     RSPCSTFKIVSTLIGLEKGVINSKESVMGYDGTEYPNKNWNKNLSLEEAFKESCVWYY
                     KKLIDKVDAKSVQNILDDLKYGNCDISEWEGDLKNGKGHLNGFWLESSLQISPKEQVQ
                     TMAKIFEGDTNFKKEHINILRDIMKIDINDKNINVYGKTGTGFDEKNKRVDAWFVGML
                     EREGDTYYFAIKSDDSNKEITGPKVKEIAINIIKKYYSVRE"
     gene            1575..2258
                     /locus_tag="PC512_003864"
     CDS             1575..2258
                     /locus_tag="PC512_003864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2443508.1"
                     /translation="MEILKCENLTKIYGSNQTRVTALNNVNLSVQKGDFVSIVGASGS
                     GKSTLLHLLGGVDRPTSGKIYVEDTEISSLKEEALAVFRRRKVGLIYQFYNLIPTLDV
                     RKNILLPMLLDKRKVDEDRFSEIVSILGLSDRLNHLPSQLSGGQQQRVSIARSLIYRP
                     AILLADEPTGNLDRKNSEEIVDLLNLSNKRFNQTILLITHDEKIALEANRIVTMEDGV
                     IVSEKVVKK"
     gene            2255..4915
                     /locus_tag="PC512_003865"
     CDS             2255..4915
                     /locus_tag="PC512_003865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2443509.1"
                     /translation="MNILQEYTLDFVRRNKRSSIAIMLAILLTTTMMSSLCGLLYTMW
                     TDFIRLSIEKEGNWHGELFDYTYGSDLPLIENFSSVDDVMVKGQWYVGKINDEKRDYI
                     IYRNATSEYWNSMPEKDTIIEGRRPNNANEIALSKQYFENNPSVKIGDKITLPIGYRI
                     LNGKPLEPIAPKSKGESFKKISEATLTIVGKVDVSTSSVIPAYTALGYLDKTSIKPND
                     SITVYLRFKNIRDTYKELPKLAKSLGWKTNEYGKYNLKYNSNYLLKMLVFSPEQKASM
                     SSISKFSTPIMYLTIAIFTVAVFVMVIYNAFSLSANARLTQLGILSSVGASPKQIKRS
                     VVFEGFLLTIIPLPIGLFLGWLLCNRLIVYVNSVNYHTDVPEVVFTYGIPAFLPAVLL
                     TIVTVWISALIPARKVSKISPIEAIRQGDSVKIKKSHKYSLGKIFGIEGELASNALRA
                     RKKSYRTATISLTLSFLLLTCFLHIIANQEGAKAVYGSDNYKDQRDIAVYLENSEPIE
                     SAFIEKLDNTEGVKSSLYYQKMSASTWLTEKDASKELAKNGGFKSIVSSKKYSPIERD
                     GKFRIISNIIGLDDKSFTEYCRQISVDPKLFYNTKNPTSIVYNKEEDINRSTRRNKVY
                     IDYLNLSIGDNIKLNEKVYDEDKGDYTYNMKVGAITSTLPKIVDTSSKYTLMQIVPMS
                     MVQEISKNYDEVSRLRSNRLIGVFKVNNREDIPRVREKLESIYNKDYGSGDYSIEDVL
                     ESEKQKASGIKTMNLIVGFITGLLAMIGLSNVLATVSGNIRSRRQEFAMLRSVGLSPE
                     GIKKMLILEGLFLGITPLLLSIPVQIGIVYAFLRINEIYFIEYLPFAPISTIIGFTIL
                     ILFIVIASYMTGYKQLKNENIVESIKNETI"
     gene            complement(5096..6277)
                     /locus_tag="PC512_003866"
     CDS             complement(5096..6277)
                     /locus_tag="PC512_003866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2443510.1"
                     /translation="MKTPRNINSTVVFIIFCLIVTFLLSVILTTITSFNEYNVLSKAL
                     GASYEYNPKSTESILKSLKNSSDKDFKTGNEILSKHGYSKSTFWSKNFFYFLVISFGI
                     ISTMATVIYIIKHRTNKQKLSRINNLTQYLEEVNLGKESVLLRCEDEFSHLEDEIYKT
                     VGELRCSKEFALKERQTLSDNLADIAHQLKTPITSMSLMAQLLSENCPDEEIDYINRL
                     TNQISRLERLVSSLLTLSKLDASTLIFESKLIDVHSLLTYAIEPIEGSLREKHQTFTI
                     EASPSVEFEIDINWTLEALLNILKNCSEHIEDGGYIVAYYSQNPLYVEIIIEDNGKGF
                     AQEELPYIFNRFYRGKNASKDSIGIGLALSKSIIERQNGTLHAENCHNGGARFIIKFY
                     T"
     gene            complement(6277..6939)
                     /locus_tag="PC512_003867"
     CDS             complement(6277..6939)
                     /locus_tag="PC512_003867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2443511.1"
                     /translation="MAKILLLEDDDTITFGIKTSLEKKNHTVCCYNTIAEAKKNFDKT
                     IDLILLDLNLPDGIGYEFCQYVKSIEDTPVIFLTVRDDEKDIIRGLDMGADDYVVKPF
                     LLSVLQSRINAVLRRTHSNTNNTITCENISLNKVEVKAYLDNVEVPLTAGEYKLLLSL
                     MENKNRAMTRTKLLEMLWDVDGNFVNDNTLTVTIKRLREKLKNPPCIKTLRGIGYRME
                     DS"
     gene            complement(7071..7709)
                     /locus_tag="PC512_003868"
     CDS             complement(7071..7709)
                     /locus_tag="PC512_003868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2443512.1"
                     /translation="MSELSKRDKEKIQRENEIIDKAEKLFCLNGFDNTTMNELAKEVE
                     YTKRTIYKYFSCKEDLFFAVVLRGYKRLWDNVKIESAKGKTGFEKIKLSYFAFHKFYS
                     VEPSLLCLMGMIGIVNSEKSDTDMLFKEKFFSFNKFMFDEIQGMFEIGKNDRSIRHDI
                     EIPTLMYSSIFTLTGFFNLLSVTGKSYLNNFNIDEEKFIETTLALLIDSIKA"
     gene            7888..8493
                     /locus_tag="PC512_003869"
     CDS             7888..8493
                     /locus_tag="PC512_003869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2443513.1"
                     /translation="MKIKENVLMLDSTRGSNCFIVFDKEIILIDTGLPFMGKNIIKEL
                     KTLGIKLTDIKHILLTHHDVDHISNIKLLKEKTGAKVWAHVEDIPFIIGEKDRPGFKK
                     FIGKAISRRLIKDVEPYGENMQIGNIKIIHTPGHTPGHVCMIFEAVLFAGDLVKNKNG
                     NIVPYPNPWNWDYKKMVKSIRELDNLKYEWICMSHGTPCIK"
     gene            8997..9746
                     /locus_tag="PC512_003870"
     CDS             8997..9746
                     /locus_tag="PC512_003870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF2443514.1"
                     /translation="MRLESLVNQNYDNLNENDKIIIKQILICQREYRNFSCEKIANEC
                     NVSRATLLRLCRKIGLDSFSDLKYLLKNNQLEFVNNDNNFHDVCENYRLLMNELQKIS
                     FQDICKIIYDAETIYIYGTGNEQKSLAQEIKRIFLSVGKCVIDLFDIGEIEFMRESFQ
                     KNDLFIIISLSGETKAGIEIAKFINNHIHTISLTRLDNNTIATLCEYNLYVETQKLDT
                     LQAISYEVVGAFYALLDLLHMNYIEYRRRKE"
     gene            9743..10507
                     /locus_tag="PC512_003871"
     CDS             9743..10507
                     /locus_tag="PC512_003871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF2443515.1"
                     /translation="MKIEGLFNKYYNSFTANDKYICECILNHKEDCIKLSIDEFADKY
                     HISTSALSRFAQKLQLPGYSELRVIIRLNETEVEYKNQSKHQLMDCYNKVIDDIEKKD
                     CSIMFERMKKANRIIVFGEGYSQERVAKEMKRIFLPTGKIIYDVYGYDMIQALNHFIK
                     TDDMIFFISLNGDASTIIDFAKEMRMKGIYMVSITKMISNPLARLCDENLYIQSISIS
                     VDKQLDYDVTTPYFILIELLYIKYKMYLESEHIPRK"
     gene            10606..11427
                     /locus_tag="PC512_003872"
     CDS             10606..11427
                     /locus_tag="PC512_003872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDF2443516.1"
                     /translation="MKLYKLLILDIDGTLRDEVYGIPESAKHAIRLCQKNHCSVVICT
                     GRSMGTIQDDVLSLGVDGYIAGGGNYIQYHGELLYNQSFNQRLIKEVVCLLKKREVAF
                     SIESQEKVFMNQKAKEIFETMNQLKGTNSCINKQHIQEKITYENNIEEYKSQDIHKIC
                     LWSNEKVFDEVKNILQDKMELAQRDISSQYYEIIQKDFHKGKAIKRLQERLGVTQKET
                     ICFGDGQNDVVMFQASDVTIAMKNSHQQLKDIATSICEDIFDNGIYKELKRRNII"
     gene            11441..13105
                     /locus_tag="PC512_003873"
     CDS             11441..13105
                     /locus_tag="PC512_003873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HDF2443517.1"
                     /translation="MEKKWWQKEIVYQIYPRSFQDSNNDGIGDLQGIISRLDYLKNLG
                     ITSLWLCPIFKSPMDDNGYDISDYLDIASEFGSMEDLKELIKESKDRGIKIILDLVLN
                     HTSDEHPWFQEALKNPESPYHDYYIFKKGNDLPNNWRSVFGGSVWEKVENRDEYYFHS
                     FGKKQPDLNWENPILRSELYQMINTWSQMGVAGFRVDAITFIKKNLSFQSLESDGVDG
                     LVKCTKTVRNQPGIEKMLYELKENTFKKYDCMTVAEAAGISYDQLGDFIGEDGFFSMV
                     FDFKHADLDVASGSEWFKRISWTIPDLRKCILDSQMYVQEHGWAANFIENHDQPRATT
                     KYLLQYERNDDAVKMLGAMYFFLRGTPFIYQGQELGMTNFKRDTINDFNDLSSIDQYY
                     RSIDESYSEEEALEFVNLRSRDNARTPFPWADKENAGFSDTTPWLKVIENYKDINAQS
                     QINNSESILEFYKKMIKLRQDSEYSDCLIYGSIEPIDIESDDIIAYRRQLDLVVIDCY
                     YNFSDKPVEIRVEEKYDIVFQNLDDINLLNKTVRLKPFHAVLLKVR"
     gene            13110..14984
                     /locus_tag="PC512_003874"
     CDS             13110..14984
                     /locus_tag="PC512_003874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2443518.1"
                     /translation="MNKYNKIANELIKIIGEDNIISITHCATRLRVMVKDREIINDKK
                     VEKVDEVKGVFFTSGQYQIILGTGIVNKVYAEVEKMGLKTLSKKEQDELVKNNETGFK
                     KVMRTLADIFVPIIPVIAATGLFLGLKGCLFNDNVLGLFGMSSANIPLYIQTLVSVLT
                     ETAFAFLPAIIVWSAFKVFGGTPVIGLVIGLMLVSPILPNAYSVADPSNEIEAIMAFG
                     FIPIVGCQGSVLTAIVTAFIGANLEKWFRKHMPNVLDLIFTPFFVMLITMLVILLGVG
                     PIMHTIELKMVDIISLLIDLPLGIGGFIIGFTYPLAVITGLHHTYVMIETSLLANTGF
                     NALITLCAMYGFANIGTCLAFMKKSKNNQVKQTAVGAMLSQLFGISEPVLFGIQLRYN
                     LKPLIIMCASSGLGAAILSILHIQSNSYGLAVLPSYLMYIYDGYNLITYLLVSIFVVA
                     FCFIVTCLFGVPKEAINEDEDEELVFNENNENFVSPAKGKIVALENVPDETFSKKMLG
                     DGFAIDIIDGKIVSPISGKLETVVSSGHAFGIKGTNGEVLIHVGIDTVALNGDGFDVA
                     VKQGDMVKQGDVLVNVDLKRIHELGKSTLTMVLFPDGKKVNILDINKDVKIGQRICVE
                     "
BASE COUNT         5709 a         1748 c         2526 g         5216 t
ORIGIN      
        1 attgtaatat ttaaatatta caatagtaag ttttaaatgt ggaatcaatt attatatcac
       61 aaattaaaag gaggacagga tgttattaat agttacctaa ttatcttcgc aataggttta
      121 atcaacataa ttgtactagg tgaagaaaat ataagagata cagctattca tttagtcttg
      181 tttcttataa gtagaaccta gattggagta tattacaaat aatgtctact attttaatag
      241 taggttataa atttaaatat gggagatgat ataaattatg aaaagaaaaa agaattttat
      301 ttggatagct atcttattgg ttggtgtagt tatggtaatg tattatgtag ggaaaaaaca
      361 taacgatata aatcaaaaaa ctgataagaa ttatataaaa tctgaattaa ataagtctga
      421 attaaataaa tccaaaattg aaaacaatga taaaaacaaa aaagaaaaaa ttaatatggt
      481 tgactatagt gattgttttg aaggtattag tggaggagct attttttata atactaaaaa
      541 taaagaatat aatatatata acaaagaatt aattgaaaca agaaggtcac catgttctac
      601 ttttaaaata gtttcaactt taattggttt agaaaaaggg gtaataaact caaaagaatc
      661 agttatggga tatgatggta cagagtatcc aaataaaaat tggaataaaa atcttagttt
      721 agaagaggca tttaaggagt cttgtgtttg gtattacaaa aaattgatag ataaagttga
      781 tgctaaatct gtccaaaaca ttttagatga tttaaagtat gggaattgcg atattagcga
      841 atgggaaggc gatttaaaaa atggaaaggg acatttaaat ggattttggt tagaatcttc
      901 attacaaata tctccaaaag aacaagtgca aacaatggca aaaatatttg agggagatac
      961 aaactttaaa aaagagcata ttaatatttt aagagatatt atgaaaatag atataaatga
     1021 taaaaacata aatgtatatg gaaaaactgg aacaggattt gatgaaaaaa ataaacgtgt
     1081 ggatgcatgg tttgttggta tgctagagcg tgaaggtgac acctattatt ttgctattaa
     1141 atcagatgat tccaataaag aaattacagg gccaaaggta aaggaaattg caattaatat
     1201 aattaagaaa tattatagtg taagggaata aacttaattt tatttgtaaa tattatttac
     1261 ctatagtctg taatatttat taaataattt tactaaattg agtctatata gagcaaaact
     1321 cctttagtac ataaaatact tgctattgat tattaaattg aatacctata gatttaaagt
     1381 taataccttt taaagactat gtaatatatt aaaagtataa ataaaatata ttgcatagtt
     1441 tttgttttat attataattt taaataatgt gcaaaaacta aacaatattt ttaatagtaa
     1501 tttatatttg tattcatgtc actataatgt cattttaggt tgctaaaatt taaccataaa
     1561 ggagatgatt gtatatggaa atattaaaat gtgaaaatct cacaaaaata tatggttcaa
     1621 atcaaaccag agtgacagcc cttaataatg taaatttatc agttcaaaaa ggtgattttg
     1681 tatccattgt aggagcatct ggttctggca aatctacatt gttacatctg cttgggggag
     1741 tagatagacc tacatctgga aagatttatg ttgaagatac agaaatatca agtttaaagg
     1801 aagaagctct tgcagttttt agacgtagaa aagtaggtct tatttatcaa ttttataatc
     1861 ttatacctac ccttgatgtt agaaaaaata tattattacc catgttactt gataaaagaa
     1921 aggtggatga ggatagattc tctgagattg tatctatatt gggattatct gatagattaa
     1981 accatcttcc aagtcaactt tcaggtggac aacaacaaag ggtatctata gctagaagtt
     2041 taatctatag accagctatt ttattagcag atgagccaac tggtaatctt gatagaaaaa
     2101 attcagaaga aattgtagac ttgttaaact tatcaaataa acgatttaat cagacaatac
     2161 ttcttattac tcatgatgag aaaatagcac tagaggcaaa tcgtattgta actatggaag
     2221 atggagtgat tgtctctgaa aaggtggtga agaaatgaat attcttcaag aatacacctt
     2281 agactttgta cgacgcaata aacgtagtag tatagctata atgttagcta tattacttac
     2341 tacaaccatg atgtcttctt tgtgtggact gttgtatacc atgtggacag attttataag
     2401 actttcaatt gagaaagaag gtaactggca tggtgaattg tttgactata cttatggaag
     2461 tgacttacca ttaattgaaa atttttcttc agttgatgat gtaatggtaa aaggacaatg
     2521 gtatgtaggc aaaattaatg atgagaaaag agattatata atttatagaa atgctacatc
     2581 agagtattgg aattctatgc cagaaaagga tactataata gagggtcgtc gaccaaataa
     2641 tgctaatgaa attgcattat caaaacaata ttttgagaat aatccaagtg taaaaattgg
     2701 tgataaaatt actctcccaa taggatatag aatcttaaat ggaaagcctc ttgaacccat
     2761 agccccaaaa tcgaaagggg aaagttttaa aaaaatttca gaggctacat tgacaatagt
     2821 aggaaaggta gatgtttcta cttcatcagt aatacctgca tatacagctc ttggatatct
     2881 tgataaaaca agtataaaac ctaatgatag tataactgtg tacttgcgat ttaaaaatat
     2941 aagagacacg tataaggaac ttccaaaact tgctaaatca ttgggatgga agactaatga
     3001 atatggaaaa tacaatctta aatacaatag taattatctt ttaaagatgt tagtcttttc
     3061 accagaacag aaagcatcta tgagtagtat atcaaaattt tcaactccta ttatgtatct
     3121 tacaatagca atttttacag tagccgtgtt tgtaatggtg atttacaacg cgttttcact
     3181 gtctgcaaat gctagactta ctcagttagg gatattatct agtgttggtg catcaccaaa
     3241 acaaattaaa aggtctgtag tgtttgaagg ctttttactg acaattatac cattaccaat
     3301 aggtttattt ttaggatggt tattgtgtaa taggcttata gtttatgtta attcagttaa
     3361 ttatcatact gatgttccag aagtggtatt tacttatggt attcctgctt ttctgccagc
     3421 agttttactt acaatagtaa cagtctggat ttctgcactt ataccagcac gaaaagtatc
     3481 aaagatatct cctatagaag caatacgaca aggagatagt gttaaaatca aaaagtcgca
     3541 taaatattca ttaggaaaga tatttggaat agaaggagaa cttgcatcaa acgcactacg
     3601 tgctcgtaaa aaatcttatc gtactgcaac aatatcttta acattatctt ttttattact
     3661 tacatgtttt ttgcatataa ttgcaaatca agaaggagca aaagctgttt atggaagtga
     3721 taattataag gaccaaagag atatagcagt ttatttggaa aatagtgaac ctatagagtc
     3781 tgctttcatt gaaaaattag ataatacaga aggtgtaaaa agttcactat attatcaaaa
     3841 aatgtctgct tccacttggc tgactgaaaa agatgcatca aaagaacttg cgaaaaatgg
     3901 aggatttaaa agtatagttt catctaaaaa atactctcct atagaacgtg atggcaagtt
     3961 tcgtataatt tcaaatataa ttgggcttga tgataagagt tttacagaat attgtaggca
     4021 aatttctgta gacccaaagt tattttataa tacaaaaaat ccaacctcaa ttgtatataa
     4081 taaggaggaa gatattaatc gtagtacacg tagaaataaa gtatatatag attatttaaa
     4141 tctttcaata ggagataaca ttaaattaaa tgaaaaagta tatgacgaag ataaagggga
     4201 ttatacttac aacatgaaag tgggagctat tacaagcaca cttcctaaaa tagtagatac
     4261 tagttcaaag tatacattaa tgcaaatagt tccaatgtct atggtacagg aaatatctaa
     4321 aaattatgat gaagtaagta ggttacgttc aaataggctg ataggagtat ttaaagtaaa
     4381 taatcgtgag gacattccta gagtaagaga aaaattagag tccatttata ataaagacta
     4441 tggttcagga gattatagta ttgaggatgt tttagaaagt gaaaaacaaa aggctagtgg
     4501 aataaagacc atgaatttaa tagtaggctt tattacaggt ttattggcta tgattggatt
     4561 atcaaatgta cttgctacag tgtcaggaaa tattagaagt agacgacaag agtttgctat
     4621 gttgcgttct gttggattat ctccagaagg cataaaaaag atgcttattt tggaaggttt
     4681 attcttagga attacaccat tactacttag tattcctgtg caaataggaa tagtgtatgc
     4741 ttttctacgt ataaatgaaa tatattttat agagtattta ccatttgcac ctatatctac
     4801 aataataggt tttactatat tgatactttt tattgtaata gcatcatata tgacaggata
     4861 caagcagttg aagaatgaaa atatagtaga atctataaaa aatgaaacaa tataaacaaa
     4921 atctatttga acttatttaa aggtttcgat ttaagactac ttacaagtat agggatagtt
     4981 aagttgtttg tttaataaaa ccttaaatgt aaatagaagt atattactaa aacaatagat
     5041 aacatagaat atagatatag ctggattata ggtattttac ctataatcca gcattttatg
     5101 tgtaaaattt aattatgaat cttgcaccac cattatggca attttctgca tgtagagtac
     5161 cattttgacg ttctataata gactttgata gagcaagccc tataccaata ctgtccttac
     5221 tagcattttt accacgataa aatctattaa aaatatatgg aagttcttcc tgagcaaacc
     5281 ccttaccatt atcttctatg ataatctcaa catatagagg attttgacta taataagcaa
     5341 ctatatatcc accatcttct atatgctcac tacaattttt aagaatattt aaaagagctt
     5401 ctaaagtcca attaatatcg atttcaaatt ctaccgaagg agaagcctcg atagtaaatg
     5461 tctgatgttt ttctcttaaa gaaccttcta taggctcaat tgcataagta agaagagaat
     5521 gtacatctat aagtttgctt tcaaatatta aagtacttgc atccaatttt gataatgtaa
     5581 gtaaagatga aactagtctc tcaagtcttg agatttgatt tgtaagtctg ttaatataat
     5641 ctatttcttc atctggacaa ttttctgaaa gtaattgtgc cataagtgac atagaagtaa
     5701 ttggagtctt aagttgatga gcaatatctg caagattatc tgaaagagtt tgtctttctt
     5761 ttaaagcaaa ttcttttgaa caacgaagtt ccccaactgt tttatatatc tcatcttcaa
     5821 ggtgagaaaa ttcatcttca catcgtaaaa gtacagactc ttttcctaaa ttcacttctt
     5881 ctaagtattg agtaagattg tttattctac tcagtttttg cttatttgtt ctatgtttga
     5941 ttatatatat aactgtagcc attgttgaaa ttataccaaa cgatatcact agaaaataaa
     6001 aaaagttttt actccaaaat gtacttttag aatatccatg ttttgataaa atttcatttc
     6061 ctgttttaaa atccttatca ctagaatttt tcagtgattt tagtatactt tctgtagact
     6121 taggattgta ctcatatgat gcaccaagag ccttagacag tacattgtat tcattaaaag
     6181 aagttatagt tgttagaatt acactcaata aaaaagttac aattaagcag aatattataa
     6241 aaacaactgt actgttgata tttcttggag ttttcactag ctgtcctcca ttctatatcc
     6301 tatgcctctt aacgttttta tacaaggtgg attttttaat ttttctctaa gacgttttat
     6361 tgtaacagta agagtgttat catttacgaa attaccatct acatcccaga gcatttctag
     6421 taactttgta cgagtcatag ctctattttt attttccata agacttagaa gaagtttata
     6481 ttctcctgct gtcaaaggta cttcaacatt atctaaatat gctttgactt caaccttatt
     6541 caagcttata ttttcacatg taatagtatt gttagtattt gaatgagttc ttctaagaac
     6601 tgcattaatt ctggactgaa gtactgagag caaaaacggt ttaaccacat agtcatctgc
     6661 acccatatct aatccacgta taatgtcttt ttcatcatca cggactgtca aaaatatcac
     6721 tggagtatct tctatacttt taacatattg gcaaaactcg tatccaatac catcaggtag
     6781 atttaaatca agcagaatta aatcaatagt tttatcaaaa ttttttttag cttcagcaat
     6841 cgtattataa caacatacag tgtgattttt cttttcaagg gaagttttta ttccaaatgt
     6901 aattgtatca tcatcttcta aaagaagtat tttagccatt tacttttaat cctttcagta
     6961 atttagttat tccattaact aagttattag ttttatgttt aatatttttt atattagaga
     7021 tagaaaaaat tatcatttaa gtatataaac tttaatttat aaacttaggt ttatgcttta
     7081 attgaatcta ttaaaagagc aagagttgtt tcaataaatt tttcctcatc tatattaaag
     7141 ttgttcaggt atgattttcc tgttacagat agtaaattaa aaaatcctgt aagtgtaaat
     7201 attgatgaat acataagagt aggtatttca atatcatgcc taatacttct atcatttttt
     7261 ccaatttcaa acattccttg tatttcatca aacataaatt tattaaaaga aaaaaacttt
     7321 tctttaaaca gcatatcagt atccgatttt tcagagttta caataccaat cattcccata
     7381 aggcataata gagaaggttc tacagagtaa aatttatgaa aagcaaagta tgaaagtttt
     7441 attttttcaa accctgtttt gccttttgca ctttctattt taacattatc ccaaagtctt
     7501 ttatatcctc ttaagacaac agcaaagaat aaatcttctt tacatgaaaa gtacttgtat
     7561 atggtgcgtt tagtatattc aacttctttt gctaattcat tcatagttgt attatcaaat
     7621 ccattaagac aaaataattt ttctgcttta tcaataatct cattttctct ttgtattttt
     7681 tctttatctc tttttgataa ttctgacata taaattattc ctttctattg ataaaaaagt
     7741 atactgatgg tatacttatg taaatataat acttgtatac ctatagtata ctttaataaa
     7801 aaataaaatt aatatcaagt attataacta tttataactt tattaattaa ttatataggt
     7861 aaaataccaa ataaggggaa tttatttatg aagataaaag aaaatgtatt aatgttagat
     7921 agtactcgtg gctcaaattg ttttattgtg tttgataaag aaattattct tatagacaca
     7981 ggtcttcctt ttatggggaa aaatataatt aaagaattaa aaacacttgg cattaaactt
     8041 acagatatta agcatatttt attaactcat catgatgttg accatatatc taatattaaa
     8101 ttattgaaag aaaaaacagg agcaaaagta tgggctcatg tagaggatat accttttatt
     8161 ataggagaga aggatagacc tgggtttaag aagtttattg gaaaggcaat ttccagaagg
     8221 ctcattaagg atgttgaacc ttatggagag aatatgcaga ttgggaatat aaaaattatc
     8281 catactcctg gtcatactcc agggcatgtc tgcatgattt ttgaagctgt attatttgca
     8341 ggtgatttag tcaaaaataa gaatggaaat atagttcctt atcctaatcc atggaattgg
     8401 gattataaaa agatggtgaa atctataaga gaattggata atttaaaata tgaatggata
     8461 tgtatgtctc atggaactcc ttgtattaaa taataaaaat taacatggat taatagaggc
     8521 atagttgctt gtatgtatga taataattta cagcttcttt ttaatatatc atgtatattt
     8581 gtagctgtaa gcatatttat aacaatactt acaattttgt attttaacat ctataataat
     8641 agttttagct ttgttaacta tgaaatttac ttaaagaagt aaatattcaa gtaatagtaa
     8701 ttattaaata agataaaaag taaatggcag atgaattaaa gtaatttcta ccatggaaaa
     8761 tacttttgag ttagaaaaaa ctatatttta gagtatgaag agatgaagct tccgaagaaa
     8821 gcaatatcta aagtacatgt tcgaaaggat aagtactttt tggtgcctgc ttttagcagg
     8881 ttatttttat tttaataaaa ataaaatcaa atgattattt tatccttatt atttaaaact
     8941 cttccctaga aaaagcaact aatgtatatt aaaataatat ttagggagtg gaaaaaatga
     9001 gattagaatc gttagttaac caaaattatg ataatttaaa tgaaaatgat aaaattatta
     9061 ttaaacaaat attgatttgt caaagagaat accgtaattt ttcgtgtgaa aaaattgcaa
     9121 atgaatgtaa tgtttctaga gctactttat taaggctttg tagaaaaatt ggattagatt
     9181 cattctctga tttaaagtat ttacttaaaa ataatcaact agaatttgtt aataatgata
     9241 ataattttca tgatgtttgc gagaattatc gactattaat gaatgaatta caaaaaatat
     9301 catttcaaga tatttgtaaa ataatatatg atgcagaaac aatttatatt tatgggacag
     9361 gtaatgaaca gaaaagttta gctcaagaaa taaagagaat atttctttca gtaggtaaat
     9421 gtgttattga cttatttgat ataggtgaaa ttgaatttat gagagaatca tttcaaaaaa
     9481 atgatttatt tattatcatt tctttgtctg gagaaacaaa agcaggaatt gaaattgcaa
     9541 aatttatcaa caatcatata catacgattt ctttaactag gcttgataat aatacaattg
     9601 caacactttg tgagtataat ctgtatgttg aaacgcaaaa acttgataca ttacaagcta
     9661 tatcttatga agtcgtagga gcattttatg ctctattaga tttgcttcat atgaattaca
     9721 tagagtatag aaggagaaaa gaatgaaaat tgaaggactt ttcaataaat attataattc
     9781 atttacagca aatgataagt atatctgtga gtgtattctt aatcataaag aagattgtat
     9841 taaactttct atagatgaat ttgcagacaa ataccatata tctacaagtg cactttctcg
     9901 ttttgctcaa aaactacaat tacctggata tagtgaatta agagttatta tacgcttaaa
     9961 tgaaacagaa gtagaatata aaaatcaaag taaacaccaa ttaatggatt gttataataa
    10021 ggtgatagat gatatagaga agaaggattg ttcgattatg tttgaaagaa tgaaaaaggc
    10081 aaatcgtata atcgtctttg gagaaggtta ttctcaggaa agagttgcta aagagatgaa
    10141 aaggattttc ttaccaacag ggaaaattat atatgatgtt tatggttatg atatgattca
    10201 ggcacttaat cattttataa aaacagatga tatgattttc tttatttcat tgaatggaga
    10261 tgcatctaca attattgatt ttgctaaaga aatgagaatg aaaggaattt atatggtttc
    10321 tattacaaaa atgataagta atcctttagc aagattatgt gatgaaaacc tgtatattca
    10381 atctatatct atttctgtag ataaacaact ggactacgat gtaacaacac cttattttat
    10441 tttaattgaa ctgctttata ttaaatacaa gatgtattta gaaagtgaac atattccccg
    10501 aaaatgaaaa tttgtgctaa aaatgaacat attttttaaa agatatcaaa atattgatat
    10561 cttttttttt gaatgctatt atgattttga tagtaagaaa ggaagatgaa attgtacaaa
    10621 ttattaatac ttgatataga tggtacgctt agagatgagg tatatggaat cccagaatct
    10681 gcaaagcatg ctatacgttt atgtcaaaag aatcattgca gtgttgttat ttgtactgga
    10741 agaagtatgg gtacaataca agatgatgtt ttatcattag gagttgatgg atatattgca
    10801 ggaggaggta attacattca atatcatggt gaattacttt ataatcaatc ttttaatcaa
    10861 agattgataa aggaagttgt ttgtttatta aaaaagagag aagttgcttt ttcgattgag
    10921 agtcaggaaa aagttttcat gaatcaaaaa gccaaagaaa tatttgaaac aatgaatcag
    10981 ttgaaaggaa ctaattcttg tataaataaa caacatatcc aagaaaaaat aacatatgaa
    11041 aataacattg aagagtataa gtcacaagat atacataaaa tttgtttatg gtcaaatgaa
    11101 aaggtatttg acgaagtgaa aaatatacta caagataaaa tggaattagc acagagagat
    11161 atttctagtc agtattatga aattattcaa aaagattttc ataagggcaa agcaattaag
    11221 agattacaag aaagattagg agtaactcaa aaagaaacca tatgttttgg tgatggtcaa
    11281 aacgatgttg tcatgtttca agcatcagac gttacaattg caatgaaaaa tagtcatcaa
    11341 caacttaaag atatagcgac atctatatgt gaggacatat tcgataatgg aatttataaa
    11401 gaattaaaaa gaagaaatat catataaaaa ggagtaattt atggaaaaga aatggtggca
    11461 aaaagaaatc gtttatcaaa tttatccaag aagctttcaa gatagtaata atgatggaat
    11521 tggagattta cagggaatta tttctcgttt agattattta aaaaatttag gtattacatc
    11581 attgtggtta tgtccaattt ttaaatcacc tatggacgat aatgggtatg atattagtga
    11641 ttatttggat attgcaagtg aatttggaag tatggaagat ttaaaagagt taattaaaga
    11701 aagtaaagat agaggaatca aaattatatt agatttagtt cttaatcata caagtgatga
    11761 acatccttgg tttcaagaag cattaaaaaa tccagaaagt ccttatcatg attattatat
    11821 ttttaaaaaa ggaaacgatt taccaaataa ctggaggtct gtttttggtg gaagtgtttg
    11881 ggaaaaggta gagaatagag acgaatatta ttttcattct tttggtaaaa aacaacctga
    11941 ccttaattgg gaaaatccaa tattaagaag tgaactttac caaatgatta atacctggtc
    12001 tcaaatggga gtggcaggat ttagagttga tgctattaca ttcatcaaaa agaatttaag
    12061 ttttcaaagt ttagaaagtg atggtgttga tggtcttgtt aaatgtacaa aaacagttag
    12121 aaatcagcct ggaatagaaa aaatgcttta tgaattaaaa gaaaatacgt ttaaaaaata
    12181 tgattgtatg actgttgctg aagcagcagg tattagctat gaccagctag gtgattttat
    12241 tggagaagat ggtttctttt caatggtctt tgactttaaa catgctgact tagatgttgc
    12301 ttctggtagt gagtggttta aaagaatttc atggacaatt ccagatttaa gaaaatgcat
    12361 tttagatagt caaatgtatg ttcaggaaca tggatgggca gctaatttta ttgaaaatca
    12421 tgaccaacca agagctacaa caaagtatct tttgcaatac gaaaggaatg atgatgcagt
    12481 aaaaatgttg ggagcaatgt atttcttttt aagaggaacc ccatttattt atcagggaca
    12541 ggaattagga atgacaaatt ttaaaagaga taccataaat gattttaatg atttatctag
    12601 cattgaccaa tactatcgtt caatagatga aagttactca gaagaagaag cgttagaatt
    12661 tgtgaattta agaagccgag ataatgcaag aacgccattt ccatgggcag ataaagaaaa
    12721 tgcaggtttt tcagatacaa caccatggtt aaaggttatt gaaaattata aagatattaa
    12781 tgcacagagt cagattaaca attcagagag tattttagaa ttttataaaa agatgataaa
    12841 gttgagacaa gatagtgagt attctgattg tttgatttat ggttcaatag aacctattga
    12901 tatagaaagt gatgatatta ttgcgtatag aaggcaatta gatttggtag ttattgattg
    12961 ttattataat ttttctgata aacctgtaga aataagagta gaagaaaaat atgatattgt
    13021 attccaaaat ttagatgata taaatctatt aaataaaaca gtgcgtttga aaccatttca
    13081 tgcagtatta ttgaaagtga ggtagaaaaa tgaataaata taataaaata gcaaatgagc
    13141 ttattaaaat tattggtgaa gataatatta tttctattac acattgtgcc acaagattaa
    13201 gagtgatggt taaagataga gaaattatta atgataagaa agttgaaaaa gttgatgagg
    13261 ttaaaggggt tttctttact tctggacagt atcaaattat tttaggaaca ggaatagtta
    13321 ataaagttta tgcagaagtt gaaaaaatgg gattaaaaac tttatcaaaa aaagaacaag
    13381 atgaattagt taaaaataat gaaactggat ttaagaaagt tatgagaact ctagcagata
    13441 tatttgttcc tattattcca gttattgcag caacaggatt attcttggga ttaaagggtt
    13501 gtttgtttaa tgataatgta cttggattat ttggaatgtc ttctgcaaat attccattgt
    13561 atattcagac acttgtttcg gttcttacag aaacagcatt tgctttttta ccagcaatta
    13621 ttgtatggtc agcatttaaa gtatttggag gaacacctgt tattggactt gttattggac
    13681 ttatgttagt ttccccaata cttcctaatg catattctgt tgctgaccca tcaaatgaaa
    13741 ttgaagcaat tatggcattt ggatttattc ctattgtagg ttgtcaagga agtgttttaa
    13801 cagctattgt tacagcattt attggagcta atcttgaaaa atggttccgt aaacatatgc
    13861 ctaatgtatt agaccttatt ttcacaccat tttttgttat gctaataaca atgttagtta
    13921 ttttgttagg tgtaggccct ataatgcata caatagaatt aaaaatggtt gatatcatca
    13981 gcttattgat tgatttgcct ttaggaattg gaggatttat tattggattt acatatccat
    14041 tagctgttat tactggctta catcatactt atgtaatgat tgaaacatca ctattagcaa
    14101 atacaggatt taatgccctt attactcttt gtgcaatgta tggatttgcg aatattggaa
    14161 catgtctagc atttatgaaa aaatctaaaa ataatcaagt taaacaaact gcggttggag
    14221 caatgctatc tcaacttttt ggtataagtg agcctgtttt atttgggatt cagcttcgat
    14281 ataatttaaa gcctttgatt attatgtgtg catcttcagg tttaggagca gcaatattat
    14341 caattttaca tattcaatct aattcatatg gattagcagt tttaccttct tatttaatgt
    14401 atatctatga tggatataat ttaatcacat acttattagt atcaatattt gtggttgcat
    14461 tctgctttat tgtaacatgt ttatttggag tgcctaaaga agctataaat gaagatgaag
    14521 acgaagaatt agtgtttaat gaaaataatg aaaactttgt gtctccagct aaggggaaaa
    14581 ttgttgcatt agaaaatgta ccagatgaaa cattttctaa aaaaatgtta ggtgatggtt
    14641 ttgctattga tattatagat ggaaaaattg tttctcctat ttcaggtaaa ttagaaacag
    14701 tggtttcaag tggacatgca tttgggatta aaggaactaa tggagaagta ttaattcatg
    14761 ttggaattga tacagttgca ttaaatggag atggctttga tgttgctgtt aaacaaggag
    14821 atatggttaa acagggagac gttcttgtta atgttgattt aaagagaata catgaattag
    14881 gaaagtctac tttgacaatg gtattgtttc cagatggtaa gaaggtaaat attttggata
    14941 taaacaagga tgtaaaaata ggtcaaagaa tatgtgttga gtagtaggtg atatgtaatg
    15001 actacaaaag aagattatca agagtaattc aatcttttta aagtatgaga aataattcat
    15061 aaactctaaa acaattaaag aggttgtttc aaaatagaga ttgtattgca cccaaattgt
    15121 tgaaatgatg aaaatatatt taacttcata caaaaaatta aatagtggca acaattgagg
    15181 atgtgaggga gagttgcca
//
LOCUS       DAMJVG010000236        12751 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.guided.102, whole genome shotgun sequence.
ACCESSION   DAMJVG010000236 DAMJVG010000000
VERSION     DAMJVG010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12751)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12751)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12751
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.guided.102"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            427..1128
                     /locus_tag="PC512_003875"
     CDS             427..1128
                     /locus_tag="PC512_003875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanG-Cd-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HDF2443519.1"
                     /translation="MNENILIVDDEKEIADLIEVYLKNEGFTVYKFYTGKEALECIES
                     KNLDMAILDIMLPDIDGFHICQKIREKYYYPIIMLTAKIEDIDKIMGLTIGADDYITK
                     PFNPLEVVARVKTQLRRYMRYNNSYEQQSIIVNEYDIKGLIINKETHKCSLFGKEVAL
                     TPIEFSILWYLCEHQGKVVPSEELFEAVWGEKYLDNNNTVMAHIGRLREKIHEPSKNP
                     KFIKTVWGVGYTIEK"
     gene            1178..2260
                     /locus_tag="PC512_003876"
     CDS             1178..2260
                     /locus_tag="PC512_003876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF2443520.1"
                     /translation="MRTALMAFIAIIFIWILYSFILYGKFSIWIVSFFENAFRMEYKA
                     ALNLYQQIFRNSMELFMILAMVIVFFIIFRVYLNWFTKYFSEINQGIDSLIKEDVGEV
                     ALSPELLAIEKKINSIKHILEQRKFETQMAEQRKNELIVYLAHDLKTPLTSVIGYLTL
                     LRDESQISEELRKKYLSISLDKAERLEDLINEFFEITRFNLSNISLEYSTVSLTRMLE
                     QLTYEFKPTLMSKNLKYTLNVTPNMMIRCDVNKMQRVFDNLLRNAVYYSFEDTTIEIT
                     AVQEDDYIKLKFINHSNTIPEEKLERIFEQFYRLDTSRNSNSGRAGLGLAIAKEIVEL
                     HNGTITAHSENNIITFKVIIPIVGNL"
     gene            2521..3621
                     /gene="vanG"
                     /locus_tag="PC512_003877"
     CDS             2521..3621
                     /gene="vanG"
                     /locus_tag="PC512_003877"
                     /EC_number="6.3.2.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-serine ligase VanG"
                     /protein_id="HDF2443521.1"
                     /translation="MNNKKIAVIFGGNSTEYDVSLQSAFAVLENLNTEKYDIIPIGIT
                     REGNWYHYIGDYNNIQNNTWFERDTDIIPVIVSQNRVKNGIIEFLIPDAVSQNHIPNS
                     AIESCENDIKYTKLDFVFPVLHGKNGEDGTVQGLFELAGIQVIGCGTLSSALCMDKDK
                     SHKLVHSEGIKVPKSILLKYSDKFNVAELSKDLTYPLFIKPVRAGSSFGISKIYKKEE
                     LQVAVDLAFEHDNEVIIEENIDGFEVGCAVLGNNDLLVGRVDEIELSKGFFDYTEKYT
                     LKSSKIHMPARIDLDCEKRIQETAKIIYRTLGCSGFARVDMFLTPSGEIIFNEVNTIP
                     GFTSHSRYPNMMKGIGLSFEEILDKIIEVYIK"
     gene            3618..4424
                     /locus_tag="PC512_003878"
     CDS             3618..4424
                     /locus_tag="PC512_003878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HDF2443522.1"
                     /translation="MMNNILLDKNKEDKMTNTILLTKDKVYDGNLILVNAFLPVKTSE
                     DIDLIPVDTRFPSILMKREATNILQNILKSICGINEIVPVSGYRTAEEQQDIYSSSLR
                     DNGKDFTKKFVALPNHSEHQTGLAIDLGLKKEVIDFICPEFPYNGICNEFRKAALHYG
                     FIERYQCKKEEITGISQEPWHFRYVGYPHSEIINKMNLALEEYIEYIKRFSYTNCLKI
                     EDKEKIIEIFYVPIHTKEEVRISIPEQCVYQISGNNKDGFIVTFWRNRKD"
     gene            4442..6580
                     /gene="vanT"
                     /locus_tag="PC512_003879"
     CDS             4442..6580
                     /gene="vanT"
                     /locus_tag="PC512_003879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine racemase VanT catalytic subunit"
                     /protein_id="HDF2443523.1"
                     /translation="MIRNKSYAGLDYFRIIAALLIIAIHTSPLLSYSKMADFVLTSII
                     ARIAVPFFFMLSGFFLISTYNYNCNKLKSFLKNVLFIYGIAIVIYIPLNIYTGYFSMN
                     NLVPNIIKDIVFDGTLYHLWYLPASIIGASIAYFLVKKLGLKYSLVITIVIYVIGMFG
                     DSYYGFLEKIPLLKNLYGYIFEVSDYTRNGIFFAPVFFILGGIISNKSNYMSTKNSLI
                     GFLISFLLMLCEGMFLHKLGVQRHDSMYIMLLPCMYFLFTALTFLKGSRARLLRTSSL
                     IIYIIHPMMIVVIRMFSKIFGIQTVLVDNSLIHYIVVSIASFIASIIIILILKPLKKD
                     LKGEHKVNTNRAWIEIDLNNLEHNVKMIQKAMPEDCELMAVVKANAYGHSAFEVATCA
                     NQIGVKAFAVATIDEGIDLRRYGILGEILILGYTNPIRAKELHKYNLTQSVIDLNHAI
                     SLNKQKYNIKSHIKIDTGMHRLGFDVNDVRSILKAFKLKYLDICGIFTHLCVSDSLKD
                     EDVDFTNKQIECFYKLIDFLLKKGIKIPKVHIQSSYGFFNYPNLKCNYVRIGIALYGI
                     LSFPNDTTKLQLDLRPVLSLKSQVILIRKIQKDDSFGYGRVFIASRDSVIAILSIGYA
                     DGIPRNLSCGKSYVIINGCRAAIVGRICMDQLAVDITDIPNVEVGNTAIIIGRDNLSE
                     LSVSEVANNSCSISNELLSRVGRRLNVIKK"
     gene            6894..7514
                     /locus_tag="PC512_003880"
     CDS             6894..7514
                     /locus_tag="PC512_003880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HDF2443524.1"
                     /translation="MQYIQELLDLTQNYWVLATIIGLLSAFIESFIPALPLVAIVTAN
                     AAIQGLFIGCLLSWIGSGLGTTSLFLLISRFNDSKLFNKLRNSKTEKAISWMDKQGFK
                     LLFIAYACPFMPGCLVTIASAFGKKDLKDFVPAMLAGKFVMFIVISYVASDIEGFITS
                     PLKIASFILLVFLSWKIGNRVNKNLENHNYDFHHKKHHNDKDDKMI"
     gene            complement(7680..8216)
                     /locus_tag="PC512_003881"
     CDS             complement(7680..8216)
                     /locus_tag="PC512_003881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HDF2443525.1"
                     /translation="MIKETHERGGYIFALLILPFINNLYLVKYDIAYKIVLIIIYIYF
                     AYLGSLFPDIDMRGSYISKKFMLIYKLFGSRFRHRGFTHSLIALLLIYSFFKSLTIFT
                     NNNIVFSCLSSGFIIGYLSHLCLDLITKEGIELFYPITINISLLPIKTNSKTEKFISK
                     LLNFIVIFLIGYQFYILL"
     gene            complement(8329..9003)
                     /locus_tag="PC512_003882"
     CDS             complement(8329..9003)
                     /locus_tag="PC512_003882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HDF2443526.1"
                     /translation="MSLFIISQCITSFAFTPENNKFKVKPLPYAYDALEPYIDKETMK
                     LHHDKHYQAYVDKLNAALEKYPELYNYSLCELLQNLDSLPKDIATTVRNNAGGAYNHK
                     FFFDIMTPEKTIPSESLKEAIDRDFGSFEKFKQEFQKSALDVFGSGWAWLVATKDGKL
                     SIMTTPNQDSPVSKNLTPIIGLDVWEHAYYLKYQNRRNEYIDNWFNVVNWNGALENYK
                     NLKSQD"
     gene            9206..11080
                     /gene="asnB"
                     /locus_tag="PC512_003883"
     CDS             9206..11080
                     /gene="asnB"
                     /locus_tag="PC512_003883"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HDF2443527.1"
                     /translation="MDGNISIYYKGDISKKEDIKFKIKESVNNTRLSSRIEYKDEEKT
                     FDFERFNVIDAIYGNKPFEKDGKVIVFNGNIYNYHEIKEELIKKGHNFTTNDDIEVLL
                     ASYIEFGKNCVHKIKGMFNFIIYDRENESIFGARDLFGIKPLYYINKENAIIFSSEYK
                     FLLEYMKNLNINERSLQSYFSFQYVLPEDTMIQGIRLIPAGHYFRVENGILSLKRYNK
                     LEFRSSTKFFYTKNHLGNRDVNEDDIRNIVVDSIVTHMEEEKEIGTFLSGGIDSSIIT
                     TVASQINPNIKSFSAGFSVKGYSELEVAKKTADKLGIENIQINITQDEYIKSLPNVIY
                     SLDDPIADPSEVGLYFLIKEAGKHVKVALSGEGADELFGGYNIYKEYSTMKSVVNSPT
                     YIKSILGRVSELMPNIKGRNYLYRATTPLEKRYIGNAKVFENSEVKRFFFKYKEKNIY
                     EYLLSNLYRDAQKNNYDYISKMQHIDVNTWLQGDILQKISKLSTAEQVELRVPFLYKD
                     VFDVAKNLRMEQKINKNNTKVLLREAFREIVPEHVVQRKKLGFPTPIRVWLKDSLGDI
                     VKETIYNSNVDEFIDKKYAIKLLDTHLKGHRDNSRKIWTIFTFCLWHQLFIEHKNVEY
                     "
     gene            complement(11172..12608)
                     /locus_tag="PC512_003884"
     CDS             complement(11172..12608)
                     /locus_tag="PC512_003884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HDF2443528.1"
                     /translation="MICTIKPLKISIKKSTEPLIEFISDTTYKNKRSSYIKEVYFTRY
                     IGVDDSIDKYIEKIKNIDTYFFNNPTIPYIRLNNLKINFDKEQTDKMLKIFNIYNSSK
                     FNSWDLYNIDFPCKIENDTLNWTKKIAFKNTLDLFSTSMPNCTSSIIKNFAVKLLCWI
                     DYFLPKLFYNKVKTTISPKIVYFGNIKRQELFFLYFLSQLGCDILYINPNKDILDLYP
                     ECSKFSTLFELSRKTPNILEIPFERHITNINYSENTNKTSPTTNKPNSKNTLNNTNLT
                     SKKIVQDEEVELSYEDLAKLSASVVMIVVCNNENKPFKSGSGVVINNEGYILTNLHVV
                     NDGYSFLVRFENDDKVYTSYQIIKYHSDYDLAVIKVDRKCKPIPVKVSKKPVRGQKIV
                     AIGSPLGLFNTVSDGIISAFRDFETVQMIQFTAPISSGSSGGALLDMFGNLLGLISAG
                     YDDGQNLNLAVESNLVKIFANNFIEIVN"
BASE COUNT         4781 a         1452 c         2034 g         4484 t
ORIGIN      
        1 acattaaaat aaaaaggagt tgtcttaaaa ttgatttttt tctaatcaaa ttttaaattc
       61 aactcctttt ttgaattttt atataaaata acatggaaat tttagtaatg tctgtggtta
      121 catacatagg tttaattgtt ttttatatgg attgtctctg gtataataaa ttgaattgtg
      181 tttgactgat agatattttt attgaaagtt aatacctgtt atgcgataat aaggacgtgt
      241 taggggagtt tttataataa caattaatct cagtttttgt gttccaatag tagcatcaac
      301 acattctgat gtagtagttc ttttcttata aaaattagtt acaaatatgc ttgtaattat
      361 ttgatatgta aatttaccaa tattataaat gatgacctcg ataataagga gagtgaaaaa
      421 taatctatga acgaaaatat tttgattgtg gatgatgaaa aagaaatagc agatttaatt
      481 gaagtatatt taaaaaatga aggttttaca gtatacaagt tttatacagg taaggaagct
      541 ctagaatgta ttgaatctaa aaatttggat atggctattt tagatattat gcttcctgat
      601 attgatggat ttcatatttg ccagaaaatt cgagaaaaat actattatcc tatcattatg
      661 ttaacagcta aaattgaaga tatagacaag ataatgggtt taaccatagg tgctgatgat
      721 tatataacaa agccatttaa ccctttggaa gttgttgcaa gagtaaagac acaattaaga
      781 agatatatgc gatataataa ttcttatgaa caacagtcga taattgttaa tgagtatgat
      841 attaaaggat tgattatcaa taaagaaaca cataaatgta gtttatttgg gaaagaagta
      901 gcattaacac cgattgaatt ttctattctt tggtatttat gtgaacatca aggaaaagtg
      961 gttccttctg aagaattgtt tgaagctgta tggggagaaa aatatcttga taataataac
     1021 acagttatgg ctcatatagg gcgattacgt gaaaaaattc atgaaccttc taaaaacccg
     1081 aaatttataa aaactgtatg gggagtaggt tatacaattg aaaagtaaaa atattaaagt
     1141 caatcctgac tttactcaag tgagaaataa aatttttatg agaacagctt taatggcatt
     1201 tatagccatt attttcatat ggattttata ttcttttata ttgtatggta agttttctat
     1261 ctggatagta tcattctttg aaaatgcttt tcgtatggaa tataaagctg cattgaattt
     1321 atatcagcag attttccgta atagtatgga gctcttcatg atactagcta tggtgattgt
     1381 gttttttata atattccgtg tttatttaaa ttggtttaca aaatatttta gtgaaataaa
     1441 tcaaggtatt gactctctta tcaaagaaga tgttggagaa gtggctttat ctccagagtt
     1501 attggcaata gaaaagaaaa taaactcaat taaacatata cttgaacaac gtaaatttga
     1561 gacacaaatg gcagaacaac gtaagaatga acttattgtt tatcttgcac atgatttaaa
     1621 aacaccactt acatcagtta tagggtatct gacactactt cgagatgaaa gtcagatttc
     1681 tgaagaactg cgaaaaaaat atttatctat ttcgttggat aaggcagagc gtcttgaaga
     1741 tttaattaat gaattctttg aaattacaag gtttaattta tcaaatatat cacttgaata
     1801 cagtacagta agcttaactc gtatgcttga acaactaaca tatgagttta aacctacttt
     1861 gatgagtaag aatttaaaat atacactgaa tgttacacca aatatgatga taaggtgtga
     1921 tgttaataaa atgcaacgtg tatttgataa cttattacga aatgctgttt attatagttt
     1981 tgaagatact actattgaaa taacagctgt acaggaggat gattatataa agcttaaatt
     2041 tataaatcat agcaatacga ttccagagga aaaacttgag cgtatttttg aacaatttta
     2101 caggttggat acatctcgta attcaaacag tggtagagct gggttgggac ttgctatagc
     2161 taaagaaata gtggagcttc ataacgggac aataacagct catagcgaga acaatataat
     2221 tacctttaag gttattattc cgattgtagg aaatttgtaa gaatttaagt ataaaaaaat
     2281 aggaaattct ttaggataaa taaataaaga gcactcttgt tattgatata attactgtat
     2341 caaaacaaga gtgcttttat tttgatacag taattatatc aatagaaaaa tgtgaaaata
     2401 tattatgtgg aacagatgca attgtaagtg aaggttgatt ggatttgaaa tagaaaaagt
     2461 attttaacat gtttctgtag attgtataaa aataaataaa tcaacaaagg agaatcaaag
     2521 atgaataata aaaaaattgc agttatattt ggtggaaact caacagaata tgatgtatca
     2581 ttacaatcag cttttgcagt acttgagaat ttgaatacgg aaaaatatga tattatacca
     2641 attggaatta caagggaggg taattggtat cattatattg gagattataa taatatccag
     2701 aataacactt ggtttgaaag ggatactgat ataattccag ttattgtttc gcagaaccgt
     2761 gtcaaaaatg gtattattga atttttaatt cctgatgctg tttctcagaa tcatattcca
     2821 aatagtgcta ttgaatcatg tgaaaatgat attaaataca ctaaacttga ttttgtgttt
     2881 cctgtactgc atggaaaaaa tggagaagat ggaacagtgc aggggttatt tgaattggca
     2941 ggtatacagg ttattggatg tggtactctt tcttcagcat tatgtatgga caaagacaaa
     3001 tcacataaac ttgttcattc agaaggtatt aaagtaccaa aatcaatatt actaaaatac
     3061 tcagataaat ttaatgtggc tgaactgtca aaagacttaa cttatccatt atttataaaa
     3121 cctgtgcgtg caggttcatc atttggtatt agtaaaattt ataaaaaaga agagttacaa
     3181 gtagcagtag acttggcttt tgaacatgat aatgaagtaa taattgagga aaatattgat
     3241 ggttttgagg tagggtgtgc agttttagga aacaatgact tacttgttgg aagagtagat
     3301 gaaatagaat tgtcaaaagg attttttgat tatacagaaa aatatacatt gaaaagttca
     3361 aaaattcata tgccagctag aattgatttg gattgtgaga aaagaataca agagacagca
     3421 aaaattattt atagaactct tggatgttct ggatttgcta gagtagatat gtttttaact
     3481 ccatctggtg aaattatttt taatgaagtc aatacaattc ctggctttac ttctcatagt
     3541 cgttatccaa atatgatgaa aggtattgga ctgtcttttg aagaaatatt ggacaagata
     3601 attgaggtgt acataaaatg atgaataata ttttattaga taaaaataaa gaagataaaa
     3661 tgacaaatac tatcttattg actaaagata aagtttatga tgggaatcta attctagtaa
     3721 atgctttttt accagttaaa acatctgaag atatagattt aattcctgta gatacaaggt
     3781 ttccaagtat tcttatgaaa cgtgaagcta caaacatttt acaaaatatt ttaaaaagta
     3841 tatgtggaat aaatgaaata gtacctgtaa gtggatatcg tactgcagag gaacaacaag
     3901 atatatattc aagttctctg cgtgacaatg gaaaagactt tactaaaaag tttgtagcac
     3961 ttccaaatca cagtgaacat cagacagggc ttgctattga tttagggtta aagaaagaag
     4021 ttatagattt tatctgccct gaatttcctt ataatggtat ttgtaatgag tttcgtaagg
     4081 cagcactaca ttatggtttt atagagcgtt atcagtgtaa aaaagaagaa ataacaggaa
     4141 tatctcaaga accatggcat tttcgttatg tgggatatcc gcattctgag attatcaata
     4201 aaatgaatct cgctcttgaa gaatatatag aatatattaa gagattttcg tatacaaatt
     4261 gtttaaaaat agaagataaa gaaaaaatta tagaaatctt ttatgtgcct attcatacta
     4321 aagaagaagt gagaatctct atacctgaac aatgtgtata tcaaatatcg ggtaacaata
     4381 aggatggttt tattgtgaca ttttggagaa atagaaagga ctaagaaatg gaggaacaag
     4441 aatgattagg aataaatctt atgcagggct tgattatttt aggattatag ctgcattact
     4501 tataattgca attcatacat ctccattatt atcatatagt aaaatggctg actttgtgtt
     4561 aactagtata attgctcgta ttgctgtgcc attctttttt atgctatcag gcttttttct
     4621 aatttcaaca tataattata attgtaataa actgaaatct tttctaaaaa atgtattatt
     4681 tatttacggg atagctattg taatttatat tcccttaaat atttacactg gatatttttc
     4741 catgaataat ttagtgccca atattattaa ggacattgta tttgatggga ctttatatca
     4801 tttatggtat cttcctgcat caattattgg tgcaagtatt gcatactttc ttgtaaaaaa
     4861 actaggttta aagtactcac tagtaatcac tattgttatt tatgtaattg gtatgtttgg
     4921 tgatagttat tatggttttt tagaaaaaat accactatta aagaatttat atgggtatat
     4981 ttttgaagta tcagattata cacgaaatgg tatatttttt gcacctgtat ttttcatact
     5041 tggtggaata atatctaata aatctaatta tatgtcaact aaaaatagct tgattggatt
     5101 tcttatatca ttcttactta tgttatgtga gggaatgttt ttacataaac taggggtaca
     5161 gcgtcatgat agcatgtata ttatgttatt gccatgtatg tatttcttat ttacagcctt
     5221 aacatttttg aaaggttctc gagctaggtt attgcgaaca tcatcattaa ttatttatat
     5281 tatacatcct atgatgattg ttgttattcg tatgttttct aaaatattcg gaatacaaac
     5341 tgtcttggtt gacaatagcc ttattcatta tatagtggta agtatagcat cttttatagc
     5401 ttctataatt attatattga ttcttaaacc tctaaaaaaa gacttgaaag gagaacataa
     5461 ggtaaatacc aatagagctt ggattgaaat tgatttaaat aatttggaac ataatgtaaa
     5521 gatgatacaa aaagctatgc cagaagattg tgaattgatg gcagttgtaa aagctaatgc
     5581 ctatggtcat agtgcttttg aagtagcgac ttgtgcaaac caaataggtg taaaagcatt
     5641 tgcagtagca acaatagatg aggggattga tttacgtcga tatggaatac taggagaaat
     5701 attgattctt ggatatacta acccaataag ggcaaaggaa cttcataaat acaatcttac
     5761 acagagtgtt attgacctta atcatgctat ctctttaaac aaacagaaat acaacataaa
     5821 atcacacatt aaaattgata caggtatgca cagactgggt tttgatgtta atgatgtgag
     5881 gtcaatttta aaggcattta aattaaaata cttagatata tgtggcatat ttacacactt
     5941 gtgtgtttca gatagtctga aagatgaaga tgtagacttt acaaataaac aaattgaatg
     6001 tttttataag ttaattgatt ttctgttaaa aaaaggtata aaaattccta aagtacatat
     6061 tcaaagtagt tatggttttt ttaattatcc caatcttaag tgtaattatg taagaattgg
     6121 aattgcatta tacgggatat taagttttcc aaatgatacg actaaattgc aacttgattt
     6181 acgacctgtt ttatccttaa aatcacaagt aattcttatt agaaaaatac aaaaagatga
     6241 tagttttgga tatggaagag tctttattgc aagcagagat agcgtaattg ctatattatc
     6301 tattggctat gccgatggta tacctagaaa tttatcctgt ggaaaaagtt acgtaataat
     6361 aaatggttgt agagcagcaa tagtgggtcg aatttgcatg gaccaacttg ctgttgatat
     6421 tacagatata cctaatgtag aagttggtaa tacggcaata ataataggaa gagataattt
     6481 atctgaatta tctgtttctg aagttgcaaa taactcatgt agtatatcga atgaattatt
     6541 gagcagagta ggaagaaggt taaatgttat aaagaagtaa ctcaattaaa tagtaatatt
     6601 tgttgtactg tgtaatttat tttactctga ctagacattt ttagtaatat tatgtctaat
     6661 atatattttt tataacttac atgacaattt aagttataaa aaggtgatgt ttcagatttt
     6721 tattttgaaa catcaccttt tttgttataa tatataataa aataattata ccttaactgt
     6781 aaacttatat agattattta ctttttaata ttagattcat tttttgagat tggtatataa
     6841 taaacatata gagtatataa taatagttaa agttaaaaaa ggggaaaagc aatatgcagt
     6901 atatacaaga actacttgat ttgactcaaa attattgggt gttagccaca ataatcggct
     6961 tattaagtgc atttatagaa agctttatac cagccttacc acttgttgct atagttacag
     7021 caaatgctgc aatacaagga ttatttattg gatgtttgtt atcatggatt ggctcaggac
     7081 ttgggacaac ttcattattc ttattaataa gcagatttaa tgatagtaag ctttttaata
     7141 agttgagaaa tagtaaaact gaaaaagcaa taagttggat ggataaacag ggatttaagt
     7201 tattatttat agcgtatgcc tgtccattta tgcccggttg tttagttact atcgcatcag
     7261 cttttggtaa aaaagattta aaagattttg tgccagcaat gttggcagga aaatttgtaa
     7321 tgtttatagt tataagttac gtggcaagtg atatagaagg ttttataaca agtcctttaa
     7381 agatagcatc atttatatta ttggtgtttt tgtcatggaa gattggaaat agagtaaata
     7441 aaaatcttga aaatcataat tatgatttcc atcataaaaa acatcacaat gataaagatg
     7501 ataaaatgat ttagcttgta cgaaataaaa cgtatcttaa aatgatttag tactaaatta
     7561 ttttaagata cgttttattt tttgtattaa ggtacaaaat ttttagttct tttgtaaact
     7621 aaaatatata aaacttattt atacttagtt caaaatattg ttatttattt tttctacaac
     7681 tataataaaa tataaaattg atatccaatc aaaaaaataa ctatgaaatt taatagctta
     7741 gatatgaatt tttctgtttt tgagttagtt tttataggta gtaaagaaat gtttatagta
     7801 atgggataaa acaattcaat accttcttta gtaataaggt caagacacaa gtgagataga
     7861 tatcctatta taaacccact ggacaaacat gagaaaacta tattattgtt agtgaagatt
     7921 gtcagagatt taaaaaaact ataaataagt aataaggcaa ttagactgtg agtaaaccct
     7981 ctatgtctaa acctacttcc aaataatttg tatattaaca taaatttttt acttatgtaa
     8041 gaacctctca tatctatatc tggaaataaa gaacctaaat atgcaaaata aatataaatt
     8101 ataattaata ctattttata tgcaatatcg tatttaacta ggtacagatt gtttataaag
     8161 gggagtatca aaagtgcgaa tatataacct cccctttcat gtgtttcttt tatcatataa
     8221 aaatcctcct gaatcgtcac tataaacatt atattggtaa atttagacta tcttttatta
     8281 tattatatag caaacataag tttttttcaa aaggatttta atatttaatt aatcttgaga
     8341 ttttaaattt ttgtaatttt ctaaagcacc attccaattt actacattaa accagttgtc
     8401 aatgtattca tttcttctat tttgatattt taaatagtaa gcatgctccc aaacatcaag
     8461 tcctattata ggagttaggt ttttacttac agggctatcc tgatttggag tagtcataat
     8521 agataatttc ccatctttag tagctacaag ccaagcccaa ccagaaccaa agacatctaa
     8581 agcagatttt tggaactctt gcttaaattt ttcaaaagaa ccaaagtctc tatcaatagc
     8641 ttcttttaaa gattcagaag gtatggtttt ttctggcgtc attatatcaa aaaagaattt
     8701 atgattataa gctccacctg cattatttct tacagttgta gcaatatctt taggtaaaga
     8761 atctaaattt tgcaataatt cacataaaga ataattataa agctcaggat atttttcaag
     8821 agcagcattt aatttatcaa cataagcttg ataatgctta tcatgatgca gtttcattgt
     8881 ttctttatct atataaggtt caagtgcatc atatgcataa ggtaatggtt taaccttaaa
     8941 tttgttattt tcaggtgtaa aagcaaatga agttatgcac tgtgagatta taaataaaga
     9001 cataataact ggtattaata tttttttctt cataaaaatc acctcctaat atagtatttc
     9061 tagaaataaa aaaaatatga aatattaaca gataatttat aagaatttaa tagcaatttc
     9121 attttaaatt gaataagttt taaagccaaa gacaaaacta tgaaatatag aataagacta
     9181 aaggacagaa aggaattttg attatatgga cggcaatatt tcaatttatt ataaaggtga
     9241 tatatctaaa aaagaagata ttaaatttaa aataaaagaa tctgtaaata atacaagact
     9301 ttctagtaga atagagtata aggatgagga aaaaactttt gattttgaaa gatttaatgt
     9361 aattgatgct atttatggaa ataaaccatt tgaaaaagat ggaaaagtta ttgtttttaa
     9421 tggaaatata tataactatc atgaaataaa agaagaatta attaaaaaag gacacaattt
     9481 tactacaaat gatgatattg aagtcttatt ggcatcttat atagaatttg gtaagaattg
     9541 tgtacataag attaaaggaa tgttcaactt tataatctat gatagagaaa atgaaagtat
     9601 atttggagca agagatttat ttgggataaa accactctat tatataaata aggaaaatgc
     9661 aataattttt tcctcagagt ataagttttt acttgaatat atgaaaaatt taaatataaa
     9721 tgaaagaagc ttacaaagtt atttttcatt tcaatatgta cttcctgaag atactatgat
     9781 acaaggaata aggctgatac cagcaggtca ctattttagg gtagaaaatg gtatactatc
     9841 tttaaagaga tataataaac ttgagtttag aagtagtaca aaattttttt atactaaaaa
     9901 tcacttaggc aatagagatg tgaacgagga tgatataaga aatatagtag tagattcaat
     9961 agtaactcat atggaagagg agaaagaaat tggaacattt ctgtctggtg gaatagattc
    10021 atctattata actactgtgg cttcacaaat taatccaaat ataaaatctt tttctgcagg
    10081 ctttagtgtc aaaggatata gtgaattaga agtagcaaag aaaacagctg ataagttagg
    10141 tatagaaaat atccagatta atataacaca agatgaatat ataaaatcat taccgaatgt
    10201 aatttattct ttggatgacc ctatagcaga cccttcagaa gtaggtcttt atttcttaat
    10261 taaagaggca ggtaaacatg ttaaagtagc attgtctgga gaaggagcag atgaattatt
    10321 tggaggatat aatatatata aagagtatag tactatgaaa tcagttgtca attcacctac
    10381 ttatattaaa agtatattag gaagagtttc agaacttatg ccaaacataa aaggaagaaa
    10441 ttatctttat agagctacaa caccattaga aaaaagatat ataggaaatg caaaagtttt
    10501 tgaaaacagc gaagtaaaaa gattcttttt taagtataag gaaaagaata tatatgaata
    10561 cctgttgtct aatttgtata gagatgcaca aaaaaataat tacgattata taagtaaaat
    10621 gcaacatata gatgtgaata catggcttca aggcgatata cttcaaaaaa ttagcaaact
    10681 ttctacagct gagcaggttg aacttagagt accattttta tataaagatg tatttgatgt
    10741 agcaaaaaat ttaagaatgg agcaaaaaat aaataagaat aatacaaaag ttttacttag
    10801 agaggcgttt agagaaatag tcccagaaca tgttgttcaa aggaaaaaat taggatttcc
    10861 aactccaata agagtttggt taaaagattc tctaggggat attgtaaagg aaactattta
    10921 taattcaaat gtagatgaat ttatagataa aaaatatgca ataaaacttt tagatacgca
    10981 tcttaaaggt catagagata attcgagaaa aatatggact atatttacat tttgtctatg
    11041 gcatcaatta tttattgagc ataaaaatgt cgagtattaa tacttttttc aatattaatc
    11101 agagggcaaa agcatgcaat gttttcaccc tcctgattat tatggaatag gataagtaga
    11161 attttgattg attagtttac tatctcaata aaattattgg caaatatttt gacaagatta
    11221 ctttcaacag ctaaatttaa gttttgtcca tcatcatatc cagcggaaat caatcctagt
    11281 aagtttccaa acatatctaa aagagctcct cctgaactac cactagagat tggagctgta
    11341 aattgtatca tttgaaccgt ttcaaaatca cgaaaagctg aaataattcc atctgaaact
    11401 gtattaaaaa gacctagagg gcttccaatt gcaactattt tttgacctct cacaggtttt
    11461 ttactgactt taacaggtat tggcttgcat tttctatcaa cctttatcac agctaaatca
    11521 taatctgaat ggtattttat aatttggtaa gatgtataaa ctttatcatc attttcaaat
    11581 ctaactaaaa atgaataccc atcattgact acatgaagat tcgtaagtat ataaccttca
    11641 ttatttatta ctactccaga accgctctta aacggtttat tttcgttatt gcacacaaca
    11701 atcataacaa cagaagctga taactttgca aggtcttcat aagaaagttc tacttcctca
    11761 tcttgtacaa tttttttaga tgttagattt gtgttattaa gtgtattttt agagttaggt
    11821 ttattcgtag taggagaagt cttattggta ttttcactgt aatttatatt tgtaatatgc
    11881 ctttcaaaag gtatttctaa tatatttgga gtcttcctag aaagttcaaa tagagtagaa
    11941 aattttgaac attcaggata taaatcaaga atatctttat ttggatttat atataaaata
    12001 tcacacccaa gttgtgataa aaaatataag aaaaaaagtt cttgcctttt aatatttcca
    12061 aagtatacta tctttggtga aatagtagtc ttcaccttgt tataaaataa tttaggtaga
    12121 aaatagtcta tccaacacaa aagtttaact gcaaagtttt tgatgataga ggatgtacaa
    12181 tttggcatac ttgtggaaaa taaatctaaa gtatttttaa atgcaatctt tttagtccaa
    12241 tttaaggtgt cattttctat tttacatgga aagtcgatat tatataaatc ccaactgtta
    12301 aacttagaac tattataaat attaaaaatt ttaagcatct tatctgtttg ttctttgtca
    12361 aaatttattt ttagattgtt taatctaata tagggaattg taggattatt aaaaaaataa
    12421 gtatctatat ttttaatttt ttctatgtat ttatcaattg aatcatcaac acctatatat
    12481 cttgtaaagt agacttcttt aatatatgaa gaacgcttat ttttataggt agtatcagat
    12541 ataaattcaa ttagaggttc agtagacttt tttattgaaa tctttaatgg tttaatagta
    12601 caaatcatat tttttctcct ataataagat gatataatct attataaaac aacttaaaac
    12661 aatatagtac aataattttg tagtttcaaa ataaaatatg tacttgttta tataaatgat
    12721 atataattac atattaaaca tagcttttat g
//
LOCUS       DAMJVG010000237        11298 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.guided.108, whole genome shotgun sequence.
ACCESSION   DAMJVG010000237 DAMJVG010000000
VERSION     DAMJVG010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11298)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11298)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11298
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.guided.108"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            239..577
                     /locus_tag="PC512_003885"
     CDS             239..577
                     /locus_tag="PC512_003885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2443529.1"
                     /translation="MANIGKIIGDRIKVYRTKLGYSQEFLAEKAGLHPTYIGQIERAE
                     TNTSINIIMKIATALDIPLELLFANIITTEGVDNSVPLECYEMINKLTEKEQIAMLEL
                     IKCIIKYKEI"
     gene            599..916
                     /locus_tag="PC512_003886"
     CDS             599..916
                     /locus_tag="PC512_003886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2443530.1"
                     /translation="MNYIGKRLKEERKKANLTSKEFANMVGVSPWYITQIESGKKNPS
                     LKTFIKFVNILNISADVLIKDITSTGKTYLENDINEELKDLNSRELNLISQIIDIIKK
                     NKI"
     gene            1066..1743
                     /locus_tag="PC512_003887"
     CDS             1066..1743
                     /locus_tag="PC512_003887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443531.1"
                     /translation="MIVIEGSDKFKIAKEYIDVEYTLFSKVTFRYEKLKFKDNAELEK
                     IKMFKYKNGYIPNKLNLSFGYGFSSYKKQIIRETVDTLRLTEIFSSENIEDIKFIKDG
                     TKKLEISIEKVVKFKRRKKRNYVCCYCPDMYRDIKLDKESINKIYNRKIKIEREVNIF
                     EDEDVIINKKVLKFPKSWTKNMQKYWLSENKYPIHSTVIDDDRYKCCNVQYTKNRVII
                     LYYIYNH"
     gene            complement(2071..2838)
                     /locus_tag="PC512_003888"
     CDS             complement(2071..2838)
                     /locus_tag="PC512_003888"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HDF2443532.1"
                     /translation="MKRKVQVKNITIGEGRPKICVPIIGKNKKDIIKEAKELKDACLD
                     IIEWRVDFFENVENIKEVKEVLYELRSYIHDIPLLFTFRSVVEGGEKLISRDYYTTLN
                     KEISNTGLVDLIDVELFMGDEVIDEVVNFAHKKEVKVIISNHDFNKTPKKEEIVSRLC
                     RMQELGADLPKIAVMPQNEKDVLVLLEATNEMFKIYADRPIITMSMSGMGVISRLCGE
                     IFGSALTFGAAKSVSAPGQISFKELNSVLNLLHKSIN"
     gene            complement(3510..4325)
                     /locus_tag="PC512_003889"
     CDS             complement(3510..4325)
                     /locus_tag="PC512_003889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage integrase family protein"
                     /protein_id="HDF2443533.1"
                     /translation="MVKLSDAKSWAIRMSEDGCAYKSIDNYKRSLKASFFMAIQDDCI
                     RKNPFNFQLSDVLEDTTEPKIALTPEQEMGLLSFMESDKTYCKYYDDVVILLETGLRI
                     SELCGLTLELDMKNKAIMVDHQLLSDTKIGYYVEVPKTTQGKREIPMTERAYQSFERI
                     VERRKNAKAEPIIVDGYQNFLFLKQDGLPKQATHYQSMLRALVKKYNKTHEDKLPKIT
                     PHTFRHTLCTNMANKGMSPNILQYIMGHKNITMTLGYYAHGSFSSSRAEMERL"
     gene            4417..5685
                     /locus_tag="PC512_003890"
                     /pseudo
     CDS             4417..5685
                     /locus_tag="PC512_003890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331151.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            5784..6404
                     /locus_tag="PC512_003891"
     CDS             5784..6404
                     /locus_tag="PC512_003891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HDF2443534.1"
                     /translation="MHLIDFMNEDIKKKLVKKTYKKKETILFAEQENEYVILMIDGIA
                     EAFILNVKGNISTIHLYRSGSFFGEMEQFNDGKKPVEIVAFTDCNVYKLHRDDFLNWL
                     RGDFEATKFLIREISSKLVVNAELIEELSSLSVKERLLRCISLHYYRSELNLLTKKQL
                     ASEVNAPIRSINRAINECVQEHLIAYENKRFSVINQREVLKNLPTT"
     gene            complement(6628..6855)
                     /locus_tag="PC512_003892"
     CDS             complement(6628..6855)
                     /locus_tag="PC512_003892"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443535.1"
                     /translation="MIVACNALTQLLYSWLATVFSNASIYWGASNSIFLTPRGNLPKR
                     SCINGASTDCLKKDKKSIVSNSSLRPILVQA"
     gene            7083..8009
                     /locus_tag="PC512_003893"
     CDS             7083..8009
                     /locus_tag="PC512_003893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2443536.1"
                     /translation="MSDILSRITNKIGDKNIVDKLSALSKSDLNSLLLEVFDRQANTL
                     TATDILKSYQLNRFTIPSGIDPEEIHALESKLLRKAFNMDIKTIMLSPSAPLGSCSVF
                     GSVDQYNVVSALRGTETLADPSNMLAIIIADKLKRKEENNTIPIHMATTARVIRAQNF
                     VGKGLYSHFGLYCMVSSGIDTGSYTCEKMLLEKHLNYYKDILSEIENVRFSIILRKRN
                     GYKDNDGFFDRMVETIKLIFPNIELSIHNDDVDNNYYKGINFKLSVKQGNETVEIVDG
                     GFVDWTYQMLGNKKERCLISGIGLERFLVAVS"
     gene            8023..8472
                     /locus_tag="PC512_003894"
     CDS             8023..8472
                     /locus_tag="PC512_003894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2443537.1"
                     /translation="MELIEWNYAYITDLVEFANDKEIAKNLRDNFPHPYREQNARDFV
                     SFCLATPDVKQLSYAIFYQERAIGSISLTFEEDTSINKNAELGYWLARNYWGKGIATN
                     AVKEICKIAFEKYNLNKIHANVYSYNRGSSKVLEKCGFKIEEYCHNS"
     gene            8832..9239
                     /locus_tag="PC512_003895"
     CDS             8832..9239
                     /locus_tag="PC512_003895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF2443538.1"
                     /translation="MVDEKTIEHQFDSFCKTVLRNYARDIYDENKRRNDYLVSLESLS
                     LAELSKLSILDDYDSNYICMVSYDYNIRIEDVLMAQAIGKLTKRKQDIILLSFFLNMT
                     NADIATLMDLAENTIHYHKTNALKELKELMEEH"
     gene            9241..9471
                     /locus_tag="PC512_003896"
     CDS             9241..9471
                     /locus_tag="PC512_003896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2443539.1"
                     /translation="MKPTKEVLPFTIILLAVHGDVNAINGILKHFEHYIIRLSQKTLF
                     DEYGNPYIHVEEETKRMLGTKLITAILRFNLS"
     gene            9861..10064
                     /locus_tag="PC512_003897"
     CDS             9861..10064
                     /locus_tag="PC512_003897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HDF2443540.1"
                     /translation="MNNTDVPIWEKYTLTIEEASKYFRIGEKKLRKLADENLDSGWVI
                     MNSNRIQIKRKQFEKIVDTLDFI"
     gene            10142..10495
                     /locus_tag="PC512_003898"
     CDS             10142..10495
                     /locus_tag="PC512_003898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase DNA-binding domain-containing protein"
                     /protein_id="HDF2443541.1"
                     /translation="MSTEKRRDNKDRILRTGESQRKDGRYAYKYVYSFGKPQFVYSWK
                     LVPTDKPPKGKRDDISLRDKEKAIQNDLDDSIDTIGKKMTVCQLYAKKNGLRKNIRLN
                     TKKGRHYLMKILNKE"
     gene            10567..11199
                     /locus_tag="PC512_003899"
     CDS             10567..11199
                     /locus_tag="PC512_003899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CatB-related O-acetyltransferase"
                     /protein_id="HDF2443542.1"
                     /translation="MTIPSSNKVYPRSNDYQTVYLKNVITRENIEVGDYTIYNDFYND
                     PRDFEKNNVLYHYPINNDKLIIGKFCSIACNAKFLMTSGNHSMKSKSTYTFPIFYEEW
                     KLDINHITDAWDNKGNIIIGNDVWIGYDSIIMSGVNIGDGAIIGTRAVVTNDVPPYSI
                     VGGVPAKIIKKRFNNDTISKLLEIKWWDWPYKKIQSNIKHIQSGNIDKLV"
BASE COUNT         4134 a         1623 c         1787 g         3754 t
ORIGIN      
        1 taacatatta ttaattcgtt ttattattgt agtatggtta tgaaattatg aaaatatttc
       61 tctaattaaa aatatgattt atccatattt gtttattgta gatacagact atacaaaaat
      121 aaatagcact tatttcagta taaaaacata tatagtctat atttagacta aaaaagtata
      181 aatagtctat ataaaacaac ttaaactatg aatataatct aaagtggagg gataataatt
      241 ggcaaatata ggaaaaataa taggagatag aataaaagtc tatagaacaa aattgggata
      301 tagtcaagag tttctagcag aaaaggcagg tttacatcca acatatattg gtcagattga
      361 aagagctgag acaaatacat ctatcaatat tataatgaaa attgctactg ctttagacat
      421 accacttgaa ttgttatttg caaatattat tacaacagaa ggcgttgata actctgtacc
      481 tttagaatgt tatgaaatga ttaataaatt aactgaaaaa gaacaaattg caatgctaga
      541 gttaataaag tgcatcatta aatacaaaga aatataagtg agggaaatag taacaataat
      601 gaattatata ggtaaaagac ttaaagaaga acggaaaaaa gcaaatttaa cttcaaaaga
      661 atttgcaaat atggttggag tatcgccttg gtatataact caaatcgaaa gtggtaaaaa
      721 gaatccaagt cttaaaacat tcataaaatt tgtaaatata ttaaatattt ctgcagatgt
      781 tcttataaaa gatattactt ccactggaaa aacatattta gaaaatgata taaatgaaga
      841 gttaaaagac ttaaattcaa gagaactaaa tctgatatca cagattatag acatcataaa
      901 aaagaataaa atataattct ttatatttta tataaaaaaa aaggttattt gaaataaata
      961 accttttttt gtctttttgt gttaacattg tcttatagtg ctaatgagta ctattagacc
     1021 atgttctatg gccttatttt aatataaaac gattggagat aggctatgat tgtgattgaa
     1081 ggtagcgata aatttaagat tgcaaaagaa tatattgatg tagaatatac tctttttagc
     1141 aaagtaactt ttaggtatga aaagttgaaa tttaaagata atgctgaatt ggaaaaaatt
     1201 aagatgttta aatataaaaa tggctacatc cctaataaat taaacctttc ttttggatat
     1261 ggattctctt cttataaaaa gcaaataatt agagaaactg tagatacttt aagattgaca
     1321 gaaatttttt caagcgagaa catagaagat attaaattta taaaagatgg tacaaaaaaa
     1381 ttagaaatta gcatagagaa agttgtgaaa tttaaacgtc gaaaaaaaag aaattatgtt
     1441 tgttgctatt gccctgatat gtatagagac ataaaactcg acaaagaatc tatcaataag
     1501 atatacaaca gaaaaataaa aatagaaaga gaagttaata tttttgaaga tgaggatgtt
     1561 ataataaaca agaaagtatt gaagtttcca aagtcttgga caaagaatat gcaaaaatat
     1621 tggttaagtg aaaataagta tcccatacat tctactgtaa ttgatgatga tagatataaa
     1681 tgttgtaatg tacaatatac aaaaaataga gtgataatat tatattacat atataaccat
     1741 taatatacat aattacaaaa aaataatgac aaatatacat aatacaaata tatcttctac
     1801 tttagataaa acagttatta tgaaaactta ctatctataa ataatagaaa tgctagtata
     1861 ccatctataa tctaatgtct agtaggtttt aatggcatat tttaaatatg ccatagttga
     1921 tttataagat tttctatatc actttcaaaa tacacactaa atagttgctt ttcagatata
     1981 attgcccaat ttaaatttta ctatctgaaa agttttttat atttaattta tatcttcaaa
     2041 aataccgtct aatatttcta tataattaat ttaattaata ctcttatgta atagattaag
     2101 tactgaattt aactctttaa atgatatttg ccctggtgct gaaacacttt ttgcagctcc
     2161 aaaagtcaat gcagaaccaa atatttcacc acacaatcta cttataacac ccattcctga
     2221 cattgacatt gttattattg gtctatctgc ataaatttta aacatttcat ttgtagcttc
     2281 aagtagcact aacacatctt tttcattttg cggcataaca gctattttgg gtaaatctgc
     2341 gcccaattcc tgcattctac ataaacgaga tacaatctct tctttttttg gagttttatt
     2401 aaaatcatga ttagatataa ttactttcac ttctttttta tgagcaaaat taactacttc
     2461 atctatgacc tcatctccca taaataactc tacatctatt aaatctacta aacctgtatt
     2521 agaaatttct ttattcaaag tagtataata atctcttgat attaattttt ctcccccttc
     2581 tactacactt ctaaatgtga ataataaagg gatatcatgt atataacttc ttaattcata
     2641 gagaacttcc ttaacttctt taatattttc tacattctca aaaaaatcaa ctcgccactc
     2701 tataatatcc aaacatgcat cttttaactc tttagcctct tttataatat cttttttatt
     2761 tttcccaata attggtacac aaattttagg tctaccttct ccaatagtaa tattttttac
     2821 ttgaactttt cttttcatat tctcctccat aatcagaaat tctataggac tttaaattct
     2881 attttctgca caatttaatt atacattaaa aatactatac attataaaaa tactaattta
     2941 aaaataattt ttattctaat tcttaaaaca atcccacata ttttagaaaa ggtactctat
     3001 aatatacaaa cacttctttt ttacctaaat ttattttaac atcctataat tttcacaata
     3061 ttctttaaat tttactcata taaacaatat tattctggat gctaatagaa ttaatctata
     3121 aatcatagta taattatgca gaaataactc gaatttcact acttatgaag agattgaata
     3181 ttaatgaatc taaatcattt gcattactta agagttttga ctaaagttga acaccataca
     3241 aaagtagcta ctcaattgtt tataccccaa ccaagcttaa gtaatgttat atagattctc
     3301 gaaaaagaat ttggtatctt tttatttgaa aaacttatat taaatttgat tatcttttca
     3361 taagttggta aatgtcgata tatcctgtat ctacaaggag tatcggcatt ttctttttgg
     3421 aagatacttt gcataagttg gcatttaacc gtataagaat gccatcaaaa gtagtaaata
     3481 agtagtaaac tctagtcata ctactaggat tataaccgtt ccatttcagc tctcgaagaa
     3541 ctaaatgaac catgtgcata atagccaagc gtcatagtaa tgtttttatg ccccataata
     3601 tattgcaata tattaggact cattcctttg ttagccatat ttgtacagag tgtatgccta
     3661 aaggtatgtg gcgtaatctt tggtagcttg tcctcatggg tcttattata cttcttgact
     3721 aacgctctta acatgctttg ataatgagtt gcttgttttg gtaatccatc ttgtttaaga
     3781 aataggaagt tctggtaacc atcaacaatg attggttctg ctttagcgtt cttacgccgt
     3841 tccacgatac gttcaaatga ttgataagct ctttcagtca ttggaatttc tcgcttaccc
     3901 tgtgtggtct ttggaacttc tacataatag ccaatcttag tatcactcaa caattgatgg
     3961 tctaccataa tggctttatt tttcatatcc aattctaaag tcaaaccgca taattcagaa
     4021 atgcgtagtc ctgtttctaa gaggataaca acatcatcat aatatttaca ataagtctta
     4081 tcgctctcca taaaggataa taagcccatt tcctgttctg gtgttagagc gatttttggt
     4141 tctgttgtat cttccaaaac atcacttaac tgaaaattaa atggattctt tctaatacag
     4201 tcgtcttgaa ttgccatgaa aaacgacgct ttcagtgagc gcttataatt gtcaatggat
     4261 ttataagcac acccatcttc actcattcgg atagcccagc ttttagcgtc tgataattta
     4321 accatatcaa tgctttttgc acctagtggg tcattgatag tatctatatt ttgatttata
     4381 atttatacat ttttttaaaa acagactttt aactgtaaag aatctatgta taaacttagc
     4441 tatgttgtcc gtgtatctac aaaggatctt gacgagctaa aaaggcgttg tgatgaagtc
     4501 aaagactttt acgacgactt atcactcaag ctcgtgcgtc cctttgggga tatgttggga
     4561 ttgcatggcg aatttattcc tgtcagcaaa cgttacatca atgattatat tcaatatgtc
     4621 acttcggatt ttttggctgg acttggtttt ggagcgacac aaacccttgg cgaacatgag
     4681 gatatctatc ttggctacaa tctggacact ggaaagaatg tctatctaaa acctgccctt
     4741 gctagtcaat gggtaaaggg ttctattacc aatgtgttag cgtctgcgtt tatcggttca
     4801 ttgggtggtg gtaaattatt cagtaacaat atgcttgttt actatgcggt actattcggc
     4861 ggacaggcgg tcatagttga ccctaaagca gaacgcggca aatggaaaga aacgctacca
     4921 gaaatagccc atgagataaa cattgtcaat ttaaccagta atgatgaaaa caaaggattg
     4981 cttgaccctt acgtcatttt gagccgtaaa aatgattctg aaagtttagc gattgatatc
     5041 ctaacattcc ttgctggtat ctccagtcgt gacagtgata agttcccagt gcttagaaaa
     5101 gcaatccgca atgtaaccca aagtgaacag cgagggttat tacttgtcat tgatgaatta
     5161 cgaaaagaag atacttctat cagtaacagc atagccgacc atatcgaaag ttttgtagac
     5221 tatgattttg cacatctact gtttggtgac ggaaatgtga agcagtctat cagcttggag
     5281 aaacagctga atattattca agttgctgac ctcgtattgc cagatgccaa cactagcttt
     5341 gaagaatata caacaataga acttcttagt gttgctatgt tgattgttat tagtaccttt
     5401 gcattagact ttattcatac tgaccgctct agcttcaaga tagttgacct tgacgaagca
     5461 tggtcttttt tgcaggtggc acaaggtaaa acgctatcta tgaaactggt tagagcatcg
     5521 caagattcac aggacaaacg aattgaacgt ttgaagaatt atctgactga aaacctacaa
     5581 cagttgaata ctgaaatggt tcgctcatat attcctacta gttctattgt caacagcttt
     5641 ctcagtttga gcttactttg cagaaaaatg acaactggaa aataataatg gaatagtttc
     5701 tatgtaaata tatttttact atcttaccta actaattgaa agatgatata atttaatcaa
     5761 agatttggta aggagggatg aatatgcatt taattgattt tatgaatgaa gatattaaaa
     5821 agaagcttgt taaaaaaacg tataaaaaga aagagactat tctttttgct gagcaagaaa
     5881 atgaatatgt aattcttatg attgacggta ttgcagaagc attcatctta aatgtgaaag
     5941 gaaacatctc aactattcat ctttatagaa gtggtagttt ttttggagaa atggaacaat
     6001 ttaatgatgg gaaaaaaccc gttgaaattg tcgctttcac agattgtaat gtatataaac
     6061 ttcatagaga tgatttttta aactggttaa ggggagattt tgaagctaca aaatttctga
     6121 ttcgagaaat atctagtaaa ttagttgtaa atgctgaatt aattgaagaa ttatcatctt
     6181 taagtgttaa agaacgactt ctgaggtgta tatccttaca ctattataga agtgaattaa
     6241 atctgcttac caaaaaacag cttgctagcg aagtaaacgc tccaattaga agcattaatc
     6301 gtgctataaa tgaatgtgta caagaacatc taattgctta tgaaaacaaa agatttagtg
     6361 taattaatca gcgagaggta ttaaagaatc ttcctacaac ataagtataa tttcaaaaaa
     6421 gtattgaata ataattattc aatgcttttt tatttcgggt caagtgacct attttttttt
     6481 attttttcat tatataatac tcctatgcat aattatgttg gattgatagc taataaaaga
     6541 aagtgagagg tgttatacta aaaaagaagc atacttccca actccagact tacagtggat
     6601 tgaagataga ttttggattt gggttcatta cgcttgcact aagattggac gtagagaact
     6661 atttgaaaca attgattttt tatctttttt aagacaatca gtacttgccc cattaataca
     6721 gcttctctta ggtaaattac ctcgtggagt tagaaaaatt gaattggacg caccccaata
     6781 tattgaagca ttagaaaaga cggttgctaa ccatgaatat aaaagctgtg ttaatgcatt
     6841 gcaggctact atcaacctgt atcttgagtt aagagaggaa ttatcacaaa gtcctattgt
     6901 ccgaaaggtt gaagctgaaa gggttgcatt acagtatttt caagatttaa tcaaataaac
     6961 ccaaagtaaa aaaatattga atagtaaata ttcagtgttt tttcattttt ggtcaaatga
     7021 cctagattag ttgttgtaac cattctataa ttattttgaa agtaacagta tggaggataa
     7081 ctatgagtga tattttaagt agaattacaa ataaaattgg ggataagaat atagttgata
     7141 agttatcagc tctatcaaaa tcagatttga actcacttct attagaagtg tttgatagac
     7201 aagcaaatac tttaactgca actgatattc taaagtcata ccaactaaat agatttacta
     7261 tccctagcgg tatagatcca gaagaaattc atgctttgga gtcaaaatta ttgagaaaag
     7321 cattcaatat ggatatcaag acgattatgc tttctccctc tgctccatta ggtagctgta
     7381 gcgtttttgg ctccgtagat caatataatg tagtaagtgc tctacgaggg acagaaacac
     7441 ttgcagaccc ctcaaatatg ttggcaataa ttattgctga taaattaaaa agaaaagaag
     7501 aaaataatac catacctatc cacatggcta ctactgctag ggtaataaga gcacaaaatt
     7561 ttgtaggtaa aggtttatat tcacattttg gcttatattg tatggtttca tctggtatag
     7621 atacagggtc ttacacttgt gaaaaaatgt tgttagaaaa gcacttaaac tattataaag
     7681 atatattaag tgaaatagaa aatgttcgtt tctctattat tctacgcaaa agaaacggat
     7741 acaaagataa tgacggattt ttcgacagaa tggttgaaac tatcaaactt atttttccta
     7801 atatagagtt atcaattcat aatgatgatg ttgataataa ttattataaa ggtatcaatt
     7861 tcaaattatc ggtcaaacaa ggaaatgaaa ccgttgaaat agttgacggt ggatttgttg
     7921 actggactta tcaaatgctt ggaaataaaa aagaacgctg tttgataagt ggtattggct
     7981 tagaaagatt tcttgtagct gtttcataaa aggagaagaa aaatggaact tatagagtgg
     8041 aattatgctt atattaccga tttagttgag tttgcgaatg ataaagaaat tgcaaagaat
     8101 cttcgtgaca acttccccca cccttatagg gagcaaaacg ctagagattt tgttagtttt
     8161 tgtttggcaa ctccagatgt taaacaactt agctatgcta ttttttatca agaaagggct
     8221 attggaagta tcagcctaac atttgaagaa gatacctcta ttaataaaaa tgctgaatta
     8281 ggttactggc ttgctaggaa ctattggggc aaagggatag caacaaatgc agtaaaagaa
     8341 atatgcaaaa ttgcctttga aaaatacaac cttaacaaaa ttcatgctaa tgtatattcc
     8401 tacaatagag ggtcaagtaa agtattggaa aaatgtggtt ttaagattga agaatactgt
     8461 cacaattcat aataaagaat agaaacatga ttgattgcca tgtatatagt ttaattcgac
     8521 cgcaatagca tttattagaa ttaacctact ttttaataac agaataagtt tttcccctct
     8581 attaatttct tatgcatctt tgtattttta tgaaaagcta gccaatgcat atttccatac
     8641 atcaatatgg tggtggctta caaccaatat aaattaaata cgttttaaag aatacacatt
     8701 tttgccctat aggcagagtg tgtatttttt tctctttttt ttgaaattta tcgaagattt
     8761 aacgccctcc caccgtgata ggagtaagca aggttattta actccttgcg atggaaagag
     8821 ggtgaaatct tatggttgat gaaaagacaa ttgaacatca attcgacagt ttctgtaaaa
     8881 cagttttgcg taactatgct agagatattt atgacgaaaa taaacgcaga aatgattatt
     8941 tggtatctct cgaatctttg tcacttgcag aattaagtaa attgagtatt ttagatgatt
     9001 atgattctaa ctacatctgt atggtttctt acgactacaa catacgaatt gaagatgtat
     9061 taatggcaca agcaatcgga aaacttacaa aaagaaaaca agatataatt ctactttcat
     9121 tctttctcaa catgacaaat gctgacatag caacattgat ggatttagca gaaaatacca
     9181 tacattatca caaaacaaat gcactaaaag agttgaaaga actcatggag gaacattgaa
     9241 atgaaaccta ctaaagaagt attacctttt acaattattt tacttgctgt acatggcgat
     9301 gtaaatgcaa taaacggaat acttaaacat tttgaacact atatcattcg tctttcacag
     9361 aaaactttat ttgatgaata cggaaatccc tatattcatg tagaagaaga aacaaagcga
     9421 atgctaggaa caaaactaat cactgctatt ttgagattta atttgtctta atctcgccct
     9481 ctctccatgt atcaagctat ttggtacatg gagaatcact aattatttgt ctataaaagc
     9541 ccataagcta ttgtgatttt ttatagacaa atcaatgccg actgttcttt gacaactgaa
     9601 taaagtagat agatacgttt gtgatacaga tagccaacaa atactatacg ccatgacctt
     9661 aatcaagaga gctactatat agtgatttgt gaataacctt tggaacggtt gttttgccgt
     9721 aacctgtacc acagtataat gatacacctg tatgacacgg ttctgcccat aagaatggga
     9781 ttggttaaaa taccaatgga gcttaccaaa gccatctatc tacttctgaa ctacgaacat
     9841 agaaaggagt gatacattct atgaacaata ctgatgtacc tatttgggaa aaatatacct
     9901 tgacgattga agaagcgtca aaatactttc gtattggaga gaaaaaatta cgtaaacttg
     9961 ctgatgaaaa ccttgattct ggctgggtca ttatgaatag caatcgcatt caaataaaga
    10021 gaaaacaatt tgagaaaatc gttgatacac ttgactttat ctaatgaaat tgagccttat
    10081 atgttataat attcatatga cgtatcaagc tcaattcggt tattgagagg agcttcttat
    10141 catgtcaact gaaaaaagac gagataataa agatagaatt ttaagaactg gagagagcca
    10201 gagaaaagat ggaagatacg catataagta tgtatattca tttggtaaac cacaatttgt
    10261 ttactcttgg aaacttgtac ctactgataa acccccaaag ggaaaacgtg atgatatatc
    10321 attaagggat aaggaaaaag caatacaaaa tgaccttgat gatagcattg acactattgg
    10381 taagaaaatg acagtttgtc agttatacgc taaaaagaat ggactaagaa agaatatccg
    10441 acttaacact aaaaaaggac gccattatct tatgaagatt cttaacaagg agtgattctg
    10501 tgaagagatg tattgtagta gtggaatagt caaaaacata atatatatta aaggagagat
    10561 ttaaatatga ctattccaag ttcaaataag gtatatccaa gaagtaatga ttatcaaact
    10621 gtatatctta aaaatgtaat aacaagggaa aatatagaag ttggagatta cacaatatat
    10681 aatgactttt ataatgaccc aagagatttt gagaaaaaca atgtattgta tcattaccct
    10741 ataaacaatg ataaattaat aattggtaag ttttgctcaa tagcatgtaa tgcaaaattt
    10801 ctaatgacta gtggaaatca ctcaatgaaa tcaaaatcca catatacttt tcccatcttt
    10861 tatgaagaat ggaaactcga tatcaaccat ataacggacg cttgggacaa taagggtaac
    10921 attataattg gaaatgatgt gtggataggt tatgattcta taattatgtc aggtgtaaat
    10981 attggtgatg gtgcaattat tggaacaaga gcagtagtta ctaatgacgt tccaccgtat
    11041 tctattgttg gaggagtacc tgcaaaaatt ataaaaaaga gatttaataa tgatacaatt
    11101 tcaaaattat tagaaattaa atggtgggat tggccatata aaaaaattca atcaaacatt
    11161 aagcatattc aatcaggaaa tattgataaa ttagtttaat attttataat ttatttatat
    11221 taaactttac tttaataatc attttataag agctttttca aaatttgtat attattttaa
    11281 tatatataaa tttaatac
//
LOCUS       DAMJVG010000238         3425 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain SH657 isolate JH271
            SAMN32366124-rid16590013.guided.168, whole genome shotgun sequence.
ACCESSION   DAMJVG010000238 DAMJVG010000000
VERSION     DAMJVG010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366124
            Sequence Read Archive: SRR22863038
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3425)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3425)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560894.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560894.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:45:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,901
            CDSs (total)                      :: 3,813
            Genes (coding)                    :: 3,764
            CDSs (with protein)               :: 3,764
            Genes (RNA)                       :: 88
            rRNAs                             :: 8, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 23 of 49
            Pseudo Genes (incomplete)         :: 25 of 49
            Pseudo Genes (internal stop)      :: 13 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3425
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366124-rid16590013.guided.168"
                     /strain="SH657"
                     /isolate="JH271"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2017-03"
     gene            318..1034
                     /locus_tag="PC512_003900"
     CDS             318..1034
                     /locus_tag="PC512_003900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2443543.1"
                     /translation="MNSYNILVVEDEKEIADAIEIYLLNQGYNVFKGYNGLEGLKVIE
                     NQEIHLAIVDIMMPKMDGITLTMKLRENYNFPVIMLSAKSEEVDKIMGLNIGADDYVT
                     KPFKPLELLARVNSQLRRYTKYLNMVGNKEQKVESDDSVFAIGGLELNENTKEVSIDG
                     KYIKTTPIEFKILSLLMRNAGRVFSADEIYERVWNENAVNTDTVMVHVRNIREKIEID
                     PKNPKYLKVVWGVGYKIEKI"
     gene            1009..3342
                     /locus_tag="PC512_003901"
     CDS             1009..3342
                     /locus_tag="PC512_003901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF2443544.1"
                     /translation="MDTKLKKFKDKYIVTIIVFILMLSASLGMISQYSTIQASAKGGA
                     ENPFEQESFVDSIYKGSYVLYHNMKEEQEGKMIQPSKLFINEETMNYIKNVSKEKDTY
                     DGSETYYTDDSINADFNENFENWEHFIKASGKNLKYYLVDKESNFEFFNDNKELGVLD
                     TTKNDASKENSNENQSKNTEMNDEERQKQITDIKENYRFYVVMNFDKDGKVNIVDSYG
                     VNQKIINQMLLSKAREDLMDTSLGGNSISYKLSPIKNITLVYAVPKVISKGDSVEYGY
                     GNTYFDDGIISYISNVENNSYYKISGMILKIILAIVVIVALAFPYRKSKELLGFDTLS
                     RIPLEILFIALAIIQGLVDLYPTVIISNTLSGNYVEYLINNDISAKMASILVSLMNLT
                     YWFVIFSIIFVFIILLKHILNVGIREYFTKHTVTGMFFVWLKKAGKAVINQIRTINLK
                     EKPNKTIVTILGINLLIIVIMCSMWFFGIILALIYSVVLFKILSDYSKKTIYEYNQLL
                     DVTKKISDGNLDVNMEKDLGFFNPIKDELGNIQTGFKKAVDEEVKSQKMKTELISNVS
                     HDLKTPLTSIITYIDLLKDESITDENRKLYIDTLDRKSQRLQHLIEDLFEVSKANSGD
                     VYLNIVNVDIVSLMKQTLLELDDKLADSSLIVKNNFSNEKIILPLDSQRTFRVFENLI
                     INISKYAMPNSRVYIDILETDNKVNIMLKNMSASEIDFSVDDIMERFVRGDKSRNTEG
                     SGLGLAIAKSFIELQGGKMNISVDGDLFKVTITFNKN"
BASE COUNT         1438 a          302 c          572 g         1113 t
ORIGIN      
        1 ttatatttca aatcattaat ttaattaata caataagaac tacttttttt tgtatattaa
       61 ttttaaatat atttaaatct ttagaaaatc tttagaaaag tatatgtaat atcttaagtt
      121 tttaatttta atattaagta tataaaacaa aatgaaaaaa tattaaattt aaactagaag
      181 gaggtttcta agatggacat taaatacaaa taaccagaac aaaagatata aatatatata
      241 taaatggaaa aacttctatc atattgtata atcatatatg taaagaaaat ttataaatta
      301 atataaagga gattagaatg aattcatata atattttggt ggtagaagat gaaaaggaga
      361 tagcagatgc tatagaaata tatctattaa atcaaggata taatgttttt aagggataca
      421 atggattaga aggtcttaag gttatagaaa accaagaaat acatttagct atagttgata
      481 taatgatgcc taaaatggat ggtataacac ttacaatgaa gcttagagaa aactataatt
      541 ttccagtaat aatgctatct gcaaaatcag aagaagttga caaaataatg gggcttaata
      601 taggagcaga cgattatgta acaaaacctt ttaagccatt agaactattg gctagagtta
      661 attcacaact tagaaggtac actaagtatc taaacatggt tggaaataaa gagcaaaagg
      721 tagaaagtga cgatagtgtg tttgcaatag gcggattaga attaaatgaa aatacaaaag
      781 aagttagtat tgatggaaag tatataaaaa caactcctat agaatttaaa atactaagtt
      841 tacttatgag aaatgcagga agagtttttt ctgctgatga aatatatgaa agagtttgga
      901 atgagaatgc tgtaaataca gatacagtta tggtacatgt gaggaatata agggaaaaga
      961 tagaaattga cccaaaaaat cctaaatatt taaaggtggt gtggggtgtt ggatacaaaa
     1021 ttgaaaaaat ttaaagataa atatatagtt actattatag tttttatact tatgttatca
     1081 gcatcattag gtatgattag tcaatattct actatacaag caagtgctaa aggtggagca
     1141 gagaatccat ttgaacagga aagctttgta gatagtatat ataaaggaag ttatgtttta
     1201 tatcataata tgaaggaaga acaagaaggt aagatgatac aaccatcaaa gctatttatc
     1261 aatgaagaaa ctatgaacta tataaaaaat gtaagtaaag aaaaagatac ttatgatggt
     1321 tcagaaactt attatacaga tgatagtatt aatgcagatt ttaatgaaaa ctttgaaaat
     1381 tgggagcatt tcattaaagc gtcaggaaag aatttaaagt actatttagt tgataaagaa
     1441 agcaattttg aattttttaa tgataataaa gaattaggag tacttgatac aacaaaaaat
     1501 gatgcttcaa aagaaaattc taatgaaaat cagtcaaaaa atacagaaat gaatgatgag
     1561 gaaagacaaa agcagattac agatataaaa gaaaactata gattctacgt tgtaatgaat
     1621 tttgataaag atggaaaagt aaatattgtg gattcttatg gagtaaatca aaaaattatt
     1681 aatcaaatgt tgttatctaa agcaagagaa gatttaatgg atacaagttt aggaggaaat
     1741 tcaatttcat ataagttatc tccaataaaa aatataacat tagtatatgc tgtacctaaa
     1801 gtaataagta aaggtgatag tgtagagtat ggttatggaa atacttattt tgatgatggt
     1861 ataatttcat atataagcaa tgtagaaaat aattcttatt ataagatttc tggaatgatt
     1921 ttaaaaatta tattagctat agttgttatt gtagctttag cattcccata tagaaaatct
     1981 aaagagttgc taggatttga tacattatca agaataccgt tagagatact ctttattgct
     2041 cttgctatta tacaggggct tgtagattta tatcctactg ttataataag taataccttg
     2101 agtgggaatt atgtagagta ccttataaac aatgacataa gtgctaaaat ggctagtata
     2161 ttggtaagtt taatgaattt aacttattgg tttgtaatat tctcaataat atttgtattt
     2221 ataatacttt taaaacacat tttaaatgtt ggaataagag agtattttac aaaacatact
     2281 gtgacaggaa tgttttttgt atggttaaaa aaagcaggaa aagcagttat taatcaaatt
     2341 agaacaataa atctgaaaga aaagccaaat aaaactatag ttacaatttt gggaataaat
     2401 ttattgatta tagttataat gtgtagtatg tggttctttg gaataatact cgcattaata
     2461 tattcagtag tattatttaa gatactgtca gattactcta aaaagacaat atatgaatat
     2521 aatcaacttt tagatgttac aaagaaaatt tcagatggaa acttagatgt aaatatggaa
     2581 aaagatttag gattttttaa tcctataaaa gatgaattag gaaatattca aactggattt
     2641 aaaaaagctg ttgacgaaga ggttaagagt caaaagatga aaacagagct tatatcaaat
     2701 gtatcacatg acttaaaaac acctctaaca tctataatca cttatataga tttattaaaa
     2761 gatgaaagta taacagatga aaatcgtaag ttgtatattg atacattaga cagaaagtca
     2821 caaagattgc aacatctaat agaagatttg tttgaagtaa gcaaggcaaa tagtggagat
     2881 gtttatttga atatagtaaa tgtggatatt gtatctctaa tgaagcagac acttttagaa
     2941 ttagatgaca aacttgcaga ttcatctcta atagtaaaga ataacttttc taatgaaaaa
     3001 ataatattac cattagatag tcagcgtaca tttagagtat ttgaaaatct tataataaat
     3061 ataagcaaat atgcaatgcc aaattcaaga gtgtatattg atattttaga aacagataat
     3121 aaagtaaata ttatgcttaa aaatatgtct gcatctgaga ttgattttag tgtagatgat
     3181 ataatggaga gatttgtaag aggagataaa tcacgtaaca cagaaggttc tggtcttggt
     3241 ttagcgatag caaaaagttt tatagaatta cagggtggta agatgaatat aagtgtggat
     3301 ggtgatttat tcaaagttac aattactttt aacaaaaatt agattagact tctttaataa
     3361 ttataaagtc tatagaataa aagaatctgg aaatatttat gtgtattctt taaataaaaa
     3421 tttat
//
